bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and laboratory signs and risk factors for nephrotoxicity, associated with antiangiogenic drugs
Authors: Grechukhina Katerina S. , Chebotareva Natalia V. , Zhukova Liudmila G. , Krasnova Tatiana N.
Published: July 2021

Background. Anti-angiogenic anticancer drugs that block the vascular endothelial growth factor signaling pathway can cause renal damage. Assessment of the risk of nephrotoxicity allows developing optimal treatment approaches and ensuring the relative safety of therapy.
Aim. To assess early clinical and laboratory manifestations and risk factors for nephrotoxicity of antiangiogenic drugs.
Materials and methods. The study included 50 patients who received antiangiogenic drugs in different regimens of chemotherapy. Demographic factors, body mass index, blood pressure levels, type of antiangiogenic drug, and concomitant therapy were assessed. Before treatment and over a period of 8 weeks, the levels of hemoglobin, number of platelets and schistocytes, D-dimer levels, serum lactate dehydrogenase (LDH) levels, as well as daily proteinuria and serum creatinine and eGFRCKD-EPI were assessed. Linear regression analysis was performed to assess risk factors for nephrotoxicity and arterial hypertension (AH).
Results. The median age of patients was 46 [3457] years, 22 (44%) men and 28 (56%) women. AH developed in 52%, a decrease in eGFR in 42%, along with a decrease in hemoglobin levels and an increase in LDH levels at 2 weeks of therapy. The numbers of schistocytes and platelets significantly decreased by 8 weeks of therapy. Risk factors for impaired renal function during treatment with antiangiogenic drugs were an initial decrease in GFR less than 80 ml/min/1.73 m2, an increase in D-dimer levels, and a decrease in hemoglobin levels by 8 weeks of treatment. The risk factors for AH during therapy were the initial decrease in eGFR less than 80 ml/min/1.73 m2 and no prophylactic anticoagulant therapy.
Conclusion. Early signs of nephrotoxicity of antiangiogenic anticancer drugs were a decrease in eGFR and AH. The independent risk factors for nephrotoxicity were the initial decrease in eGFR, an increase in D-dimer levels, and a decrease in hemoglobin levels at 8 weeks of treatment, while the prophylactic use of anticoagulant therapy reduced this risk in our study.
The state of cytokine regulation and endothelial dysfunction in the combined course of vibration disease and arterial hypertension
Authors: Babanov Sergei A. , Baraeva Rimma A. , Strizhakov Leonid A. , Moiseev Sergei V. , Fomin Viktor V.
Published: July 2021

Background. The article presents data on the state of cytokine regulation, indicators of endothelial damage when exposed to industrial vibration (general, local) and in combination with arterial hypertension.
Aim. To improve the quality of early diagnosis and prevention of vibration disease in an isolated course and its combination with arterial hypertension based on a study of the cytokine profile, biomarkers of endothelial dysfunction in this pathology.
Materials and methods. A comprehensive survey of 84 patients with isolated vibration disease from the effects of local, general, first, second degree and 61 patients with a combined course of vibration disease from the effects of local, general second degree vibration and arterial hypertension, 30 people in the control group without contact with industrial vibration and found healthy by medical examination. The levels of pro-inflammatory (IL-1, IL-8, TNF-) and anti-inflammatory cytokines (IL-4), biomarkers of endothelial damage (EDN-1, TGF-1, VEGF-A, PDGF-BB, fibronectin, Willebrand factor) were determined using the enzyme immunoassay method.
Results. The response of the immune system to the effects of industrial vibration is characterized by a cytokine imbalance an increase in the level of pro-inflammatory cytokines (IL-1, IL-8, TNF-) and a decrease in the level of anti-inflammatory cytokine (IL-4). With a combined course of vibratory disease and arterial hypertension, the cytokine imbalance is characterized by an even more significant increase in serum IL-1, IL-8, TNF- and a decrease in serum IL-4 concentration. Endothelial dysfunction with WB from the action of both local and general vibration in combination with hypertension is characterized by a significant increase in serum EDN-1, TGF-1, VEGF-A, PDGF-BB, fibronectin, Willebrand factor.
Conclusion. The study of the cytokine profile, biomarkers of damage to the vascular endothelium in this pathology will allow for the early diagnosis of vascular disorders and to optimize preventive measures for workers in vibration-hazardous industries.
Treatment of thrombotic thrombocytopenic purpura
Authors: Galstyan Gennadii M. , Maschan Alexei A. , Klebanova Elizaveta E. , Kalinina Irina I.
Published: July 2021

The review discusses approaches to treatment of acquired thrombotic thrombocytopenic purpuгa (aTTP). In patients with aTTP plasma exchanges, glucocorticosteroids allow to stop an acute attack of TTP, and use of rituximab allows to achieve remission. In recent years, caplacizumab has been used. Treatment options such as cyclosporin A, bortezomib, splenectomy, N-acetylcysteine, recombinant ADAMTS13 are also described. Separately discussed issues of management of patients with TTP during pregnancy, and pediatric patients with TTP.
The dapagliflozin and prevention of adverse outcomes in chronic kidney disease: results of the DAPA-CKD study
Authors: Batyushin Mikhail M.
Published: July 2021

Aim. The article presents the main results of a randomized, double-blind, parallel, placebo controlled trial of DAPA-CKD.
Materials and methods. The study included patients with chronic kidney disease (CKD) and the possibility of using dapagliflozin at a dose of 10 mg once a day compared with placebo. The study involved 386 centers from 21 countries. A total of 4304 patients were included in the study, the average age was 61.8 years, men predominated, 2906 (67.5%) patients had an initial diagnosis of type 2 diabetes. Patients with diabetic and non-diabetic CKD were included with an estimated glomerular filtration rate (eGFR) of 25 to 75 ml/min/1.73 m2 and a urinary albumin/creatinine ratio of 200 to 5000 mg/g.
Results. The primary composite endpoint (time to eGFR reduction of 50% or more compared to baseline, time to end-stage renal disease defined as eGFR15 ml/min/1.73 m2, need for chronic dialysis or kidney transplantation, time to renal or cardiovascular death) was shown to occur in 9.2% of patients treated with dapagliflozin and in 14.5% of patients treated with placebo. Also, dapagliflozin therapy was less likely to have a secondary endpoint, such as a combination of a decrease in eGFR by 50% or more, end-stage kidney disease, or renal death. Less frequently, the dapagliflozin group experienced cardiovascular death or hospitalization for heart failure, as well as death from any cause.
Conclusion. Thus, dapagliflozin demonstrated the ability, in comparison with placebo, to reduce the primary composite point and a number of secondary composite points in patients with both diabetic and non-diabetic CKD.
Large scale industry mill: effect of extraction rate of flour on the dough rheological properties
Authors: Alhendi A.S. , Ahmed Z.A. , Hussein M.S. , Abed S.A.
Published: July 2021

Consumption of whole wheat flour is increasing worldwide because of its nutritional
value. However, the flour rheological properties are affected by a high extraction rate
(ER), that have been mentioned for many studies done on a laboratory scale. In the present
study, a high ER flour produced by using a large-scale industrial mill was used to
determine the effect of high ER on the dough rheological properties. The three studied
extraction rates (80%, 85%, and 92%) were achieved by changing the roll adjustments and
adding fine bran. The rheological properties (farinogram, extensiogram, and amylogram
parameters) of the produced flour were determined in addition to some chemical and
physical attributes. The result showed that there were no significant differences between
farinogram parameters except for water absorption, which was increased with increasing
ER. Also, there were no significant differences for extensiogram parameters and
amylogram parameters, as well as for wet gluten and gluten index, protein, and moisture
content. Conversely, for ash content, there were significant differences between the three
flours. For PSD, there were no significant differences between produced flour related to
the large particle size (above 720 and 354 µm). In conclusion, increasing ER of produced
flour up to 92% with adding fine particle size bran had no significant effect on the
rheological properties of the produced flour compared to 80% ER.
In vitro antioxidant activity test and determination of phenolic and flavonoid content of Moringa oleifera pulp and seeds
Authors: Ruslin  , Sahumena M.H. , Andriani R. , Mamangkara M. , Mistriyani  , Yamin
Published: July 2021

Moringa oleifera is a plant that is empirically widely used as a medicine to treat
hyperglycemia, anti-inflammatory, antidiabetic, antimicrobial, anticancer, antioxidant,
gastric ulcer, skin disease, fever, fatigue, hysteria, thrush, bladder, and bronchitis.
Moringa oleifera contains secondary metabolites such as flavonoids, tannins, terpenoids,
alkaloids, and phenolics. This study aimed to investigate the antioxidant activity and
levels of phenolic and flavonoids in the extracts and fractions of moringa pulp and seeds.
The pulp and seeds of Moringa were extracted using the maceration method and
fractionated using the liquid-liquid extraction method. Antioxidant activity was measured
using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Phenolic content was measured
using the Folin-Ciocalteau method. Meanwhile, the flavonoid content was determined
using the AlCl3 colorimetric method with UV-Vis spectrophotometry. The ethyl acetate
fraction of moringa pulp and seeds had the strongest antioxidant activity with IC50 values
of 5.97 µg/mL and 5.08 µg/mL, respectively. Ethyl acetate fraction also has high phenolic
and flavonoid content in the pulp and seeds of moringa with a phenolic content of 43.956
mg GAE/g sample for pulp and 9.429 mg GAE/g sample for moringa seeds. The flavonoid
content of 94.257 mg QE/g sample for pulp and 93.719 mg QE/g sample, with the highest
correlation between phenolic compounds and flavonoids on antioxidant activity, was
obtained in moringa pulp with the highest correlation (R2
= 0.6514) for phenolic and R
2
=
0.7531) for flavonoids. In conclusion, the ethyl acetate fraction of moringa pulp and seeds
can be further developed as an antioxidant and functional food.
Assessment of sensory and microbiological quality of five marketed fish species at Dhaka city in Bangladesh
Authors: Islam T. , Mia M.R. , Folorunso E.A. , Kabiraz M.P. , Masuda M.A. , Das N.C. , Bhowmik S.
Published: July 2021

The study assessed the sensory quality and the bacterial condition in five nutritionally
important fish species at Dhaka city in Bangladesh. Sensory defect points (DP) were
analysed at in-situ conditions and microbiological attributes were conducted at laboratory
condition. Sensory DP indicated fishes in retail markets (RM) were deteriorating and/or
spoiled (DP >3 to <5) except live fishes. In super shops (SS), DP indicated excellent to
good quality (DP >1 to <3) for all the fishes. The average total plate count (TPC) in the
fishes from RM exceeds the permissible limit (PL) except for the fishes sold in live
condition. A highly significant difference observed in the fishes sold in dead condition
between RM and SS (p≤0.001). Correlation analysis revealed an insignificant relationship
between sensory DP and TPC (p≥0.05) in the markets. The study recorded total coliform
counts (TCC) was within the PL i.e., <100 MPN/g in both types of markets. Faecal
coliform counts (FCC) were within the acceptable limit i.e., <10 MPN/g only in the fishes
from super shops. Salmonella spp. and Vibrio cholerae was detected almost in all samples
from retail markets while it was very less likely detected in SS. The study revealed that
fish from both RM and SS is safe for human consumption but super shops possess better
quality than retail markets.
Effect of pretreatments and temperature on rehydration kinetics of naga chili (Capsicum chinense)
Authors: Rana M.R. , Sakib K.N. , Islam M.Z. , Das P.C. , Ara R.
Published: July 2021

Naga chili (Capsicum chinense) is rich in capsaicin content that provides a distinctive
aroma and strong pungency. Drying with pretreatment is regarded as a cost-effective
approach to retain better nutrient quality, whereas rehydration properties consider a
quality index to optimize the drying conditions. This study aimed to determine rehydration
kinetics and rehydration characteristics of pretreated hot-air dried Naga chili. The
pretreatment was consisting of water blanching (90°C for 5 mins), steam blanching (100°
C for 1 min), microwave treatment (650 W for 100 s), and dipping into sugar 70°Bx, 0.5%
citric acid, 2% ethyl oleate + 3% potassium carbonate, and 2% potassium meta bi-sulfite
solution. After drying at 60°C, the rehydration was done at 25°C, 50°C, and 75°C,
respectively. The rehydration kinetics were evaluated by fitting the experimental data into
empirical kinetic models: Peleg's model, 2nd order, 1st order, and Zero-order kinetics.
Among these models, the rehydration behavior was best described by Peleg's model,
where the highest R2
(0.9964), lowest χ
2 (0.0001) and RMSE (0.0064) values were
obtained. Different rehydration characteristics such as moisture content, equilibrium
moisture content, rehydration ratios were also determined. The highest moisture content
(8.10 g moisture/g dry sample) was found at higher rehydration temperature (75°C),
whereas the lowest moisture content ranges were recorded at 25°C. After moisture
contents got equilibrium, the rehydrated samples gain weight to 100.15% at 75°C in
comparison to the untreated samples. The rehydration ratios were also getting higher with
increasing rehydration temperatures.
Mapping the social values of ecosystem services to support better decision making
Authors:   , Mousavipour Sedigheh
Published: July 2021

Social values of ecosystem services are the perceived benefits of natural ecosystems for the well-being of people. For sustainable land management, social values and preferences need to be integrated into land-use decision-making. Existing methods of social value capture commonly use participatory mapping and deliberative mapping. However, social media data has recently contributed to the gathering of spatial social value data. By reducing the time and cost of mapping, social media may be effective in social value mapping. However, the credibility of this data source has rarely been assessed for land planning.

This thesis critically analysed the results of social media-based mapping (passive Volunteered Geographic Information (VGI)) and deliberative mapping (expert-based evaluation) methods into providing credible social value data (recreation, aesthetics, and historical/cultural values) for recreation planning. We analysed the content of 4642 photographs uploaded to Flickr as passive VGI and the results of an online survey and face to face interview for expert-based evaluation. This thesis found both the passive VGI and expert-based evaluation could identify all three types of relevant social values for ecosystem services (recreation, aesthetics, and historical/cultural).

Passive VGI can provide reasonably reliable information on the recreational preferences of people at the time that data is provided. Although social values identified in expert-based evaluation included useful information about current public preferences and a potential supply of recreation ecosystem services, it only captured a general view of the study area. Large areas of interest were provided by each of the experts participating in the online survey. Several landscape units were missed by passive VGI while expert-based dataset overrepresented a majority of landscape units.

The results of this research demonstrated that spatial social value data are limited when a single method is applied. Potential users of such data need to understand their limitations. Applying several mapping methods (PPGIS, expert-based evaluation, passive VGI, etc.) may create a more useful and credible social value dataset to appropriately support recreational planning.
Mapping the social values of ecosystem services to support better decision making
Authors: Mousavipour Sedigheh
Published: July 2021

Social values of ecosystem services are the perceived benefits of natural ecosystems for the well-being of people. For sustainable land management, social values and preferences need to be integrated into land-use decision-making. Existing methods of social value capture commonly use participatory mapping and deliberative mapping. However, social media data has recently contributed to the gathering of spatial social value data. By reducing the time and cost of mapping, social media may be effective in social value mapping. However, the credibility of this data source has rarely been assessed for land planning.

This thesis critically analysed the results of social media-based mapping (passive Volunteered Geographic Information (VGI)) and deliberative mapping (expert-based evaluation) methods into providing credible social value data (recreation, aesthetics, and historical/cultural values) for recreation planning. We analysed the content of 4642 photographs uploaded to Flickr as passive VGI and the results of an online survey and face to face interview for expert-based evaluation. This thesis found both the passive VGI and expert-based evaluation could identify all three types of relevant social values for ecosystem services (recreation, aesthetics, and historical/cultural).

Passive VGI can provide reasonably reliable information on the recreational preferences of people at the time that data is provided. Although social values identified in expert-based evaluation included useful information about current public preferences and a potential supply of recreation ecosystem services, it only captured a general view of the study area. Large areas of interest were provided by each of the experts participating in the online survey. Several landscape units were missed by passive VGI while expert-based dataset overrepresented a majority of landscape units.

The results of this research demonstrated that spatial social value data are limited when a single method is applied. Potential users of such data need to understand their limitations. Applying several mapping methods (PPGIS, expert-based evaluation, passive VGI, etc.) may create a more useful and credible social value dataset to appropriately support recreational planning.
Efektifitas Model Pembelajaran Team Quiz Menggunakan Media Zoom Meting Terhadap Hasil Belajar Siswa
Authors: Andrini Vera Septi
Published: July 2021

This study aims to determine the effectiveness of the Team Quiz learning model on student learning outcomes. In this study, the research design used a quantitative approach. The population of this study was all eighth grade students of SMP Negeri 3 Nganjuk in the 2019/2020 academic year. The subjects used were mathematics with the Pythagorean Theorem material for class VIII students at SMPN 3 Nganjuk in the 2019/2020 academic year. While the samples used were students in class VIII-E and VIII-H. Data collection techniques using tests, observations, and documentation. The results showed that the experimental class using the Team Quiz model obtained better results than the control class using the conventional method. From the data analysis of the post-test results of the experimental class, the average value = 76.23 of 35 students. While the data of the post-test results for the control class obtained an average value of 58.97 from 35 students. The achievement of student learning outcomes using conventional learning methods is Good Enough. Team Quiz is a learning model that emphasizes teamwork in groups. So that it can make students more motivated and active in learning.
The Influence of Soft Skills on Employability: A Case Study on Technology Industry Sector in Malaysia
Authors: Saad Fadhil Sally , Ismail Ramlee , Alnoor Alhamzah
Published: July 2021

Aim/Purpose: This research investigates the influence of soft skills on graduates’ employability in the technology industry, using the technology industry sector in Malaysia as a case.

Background: Organizations are looking for appropriate mechanisms to hire qualified employees with strong soft skills and hard skills. This requires that job candidates possess a set of qualifications and skills which impact their employability.

Methodology: Fuzzy Delphi analysis was conducted as preliminary study to identify the critical soft skills required by technology industry sector. The preliminary study produced ten critical soft skills to form a conceptual model of their influence on employability. Then, an online questionnaire survey was distributed in two industry companies in Malaysia to collect research data, and regression analysis was conducted to validate the conceptual model.

Contribution: This research focuses on the influence of soft skills on graduate employability in the technology industry sector, since the selection of the best candidate in the industry will improve employee performance and lead to business success.

Findings: The results of regression analysis confirmed that Communication skills, Attitude, Integrity, Learnability, Motivation, and Teamwork are significantly correlated with employability, which means that these soft skills are the critical factors for employability in Malaysian technology companies.

Recommendations for Practitioners: The model proposed in this article can be used by employers to give better assessment of candidates’ compatibility with the jobs available.

Impact on Society: This research highlights the critical soft skills required by technology industry sector, which will reduce the unemployment percentages among graduates.

Future Research: More studies are required to examine the soft skills found in the literature and to define the most important skills from a general perspective of the industry. Future research should assess the moderating role of other variables, such as skills gap, employee performance, and employee knowledge. Furthermore, it is recommended to conduct similar studies of soft skills for employability in other countries.
Estimation of Heterosis Among Potato (Solanum tuberosum L.) Crosses in Ethiopia
Authors: Workayehu Manamno , Mohammed Wassu , Abebe Tesfaye
Published: July 2021

Determination of heterosis in tetraploid potato crosses is necessary for identification of superior genotypes for variety development or breeding program. However, producing heterotic potato genotypes through local crossing is not a common practice in Ethiopia. Hence, this study was conducted to estimate the magnitude of better, and standard check heteroses in potato clones that are produced from local crossing. This will help identify potential of hybrid for future breeding schemes. Heterosis of 75 clones were evaluated using a 9 x 9 Simple Lattice design. Results of the analysis of variance showed significant differences for all the growth characters, except medium-sized tubers and specific gravity of tuber. These results indicate the presence of genetic variability among the samples. The clones exhibited as high as 55.62 and 58.31 t.ha-1 marketable and total tuber yield, respectively. These clones also displayed mid, better parent and standard heterosis of 118.8%, 90.5% and 239.1%, respectively, for marketable tuber yield. This result indicates the presence of high magnitude heterosis which could be used to exploit the hybrid vigor. In addition, mid, better parent, and standard check heterosis were estimated at 79.36%, 61.04% and 209.17% for total tuber yield, respectively. Our results show the highest chance of getting heterotic offspring than parental and standard check varieties to developing new potato varieties.  The information generated from this study would be valuable for researchers who intend to develop high-yielding varieties of potato
Influence of Sowing Dates and Sowing Methods on Growth and Seed Yield of Black Cumin (Nigella sativa L.)
Authors: Waliullah Md. , Mokter Hossain Md. , Habibur Rahman Md.
Published: July 2021

Nigella sativa L. is widely used medicinal plant throughout the world. In Bangladesh it is mainly used as spices in preparing various food items. Sowing time and sowing methods are the influential factors to produce higher seed yield of black cumin. Therefore, this study was undertaken to find out a suitable sowing date and method to produce higher seed yield of black cumin. The two-factor experiment comprised with four sowing dates (1st November, 15th November, 1st December and 15th December) and two sowing methods (line sowing and broadcast seeding). The experiment was carried out following randomized complete block design with three replicates. Results showed that plant growth, yield contributing traits and yield of black cumin significantly influenced by sowing dates and methods. It was observed that the line sowing method compared to broadcast seeding and 1st December sowing among the other sowing dates exhibited higher plant growth with greater production of seed. The combine effect of sowing time and sowing methods showed significantly influenced on black cumin seed production. It was observed that the 1st December sowing with line sowing method increased the seed yield as compared to other sowing dates and methods. From the findings of this study it can be concluded that 1st December following line sowing method would maximize plant growth, yield contributing traits and seed yield of black cumin in Bangladesh.
The Effects of Different Rates of Chicken Manure and Harvest Intervals on the Bioactive Compounds of Bitter Leaf (Vernonia amygdalina Del.)
Authors: Betty Betty , Aziz Sandra Arifin , Suketi Ketty
Published: July 2021

Bitter leaf (Vernonia amygdalina Del.) is a valuable functional vegetable and traditional medicinal plant in many tropical countries including Indonesia. Bitter leaf is commonly used to remedy hypertension and diabetes among Indonesian people. The leaf extract comprises bioactive compounds such as sesquiterpene lactones, steroid glycosides, and flavonoids. Despite its growing market demand, there is insufficient data on agronomic practice in order to obtain optimum yield with high bioactive compounds.  The experimental design used was a randomized complete block design with two factors namely chicken manure rates (0, 2.5, 5, and 7.5 kg per plant) and harvest intervals (2 and 3 months). There was a significant difference in fresh and dry weights of leaves, chlorophyll a and b, carotenoids, nitrogen concentration, anthocyanins, and flavonoids among different manure treatment. The highest concentration and production of bioactive compounds on the bitter leaf was found on the highest treatment of 7.5 kg chicken manure per plant. The harvest interval of three months significantly increased fresh and dry weights of leaves, concentration of anthocyanins, phosphorus, and potassium, uptake of phosphorus and potassium, and production of anthocyanins and flavonoids. Cultivation using chicken manure with frequent period of pruning can enhance the production of biomass as well as secondary metabolites in bitter leaf.
Hybrid Vigour Study of Yield and Yield Related Characters on Limmu Coffee (Coffea arabica L.) Genotypes at South-Western Ethiopia
Authors: Asefa Gemechu , Mohammed Hussein , Ayano Ashenafi
Published: July 2021

Coffee (Coffea arabica L.) is one of the most important crops cultivated worldwide and has a great economic impact in many countries including Ethiopia. Hybrid vigor (heterosis) breeding can enhance productivity of coffee. Hybrid vigor study was conducted on 5 x 5 half-diallel mating involving 17coffee genotypes (5 parents, 10 F1 hybrids and two checks) for yield and its related traits in 2018. The study locations include Jimma, Agaro and Gera research centers of south-western Ethiopia using randomized completely block design with three replications. There are significant differences among 17 genotypes and 15 diallel genotypes (checks excluded) for all traits; the crosses showed significant and positive average heterosis (mid parent) and heterobeltiosis (better parent) for all traits. Crosses showed significant variation in the expression of standard heterosis (SH) and useful heterosis (UH) for fruit length (FL), fruit width (FW), bean length (BL), bean width (BW), bean thickness(BT), and hundred bean weight (HBW) across locations. Heterobeltiosis ranged from -9.06 to 88.79% and -17.81 to 67.98% for yield at Jimma and Gera, respectively. Mean SH and UH was positive and between 5 and 10% for BL and BT and <5% for all fruit characters and BT across locations. Mean of SH and UH was 14.62% and 11.82%, respectively for HBW. Crosses P4 x P5, P1 x P5 and P2 x P5 increased yield by 25.13% (637.75 kg), 14.05% (356.64 kg) and 5.78% (146.59 kg) over commercial pure line variety across three locations, respectively. Based on heterosis and mean performance hybrids P4 x P5, P1 x P5, P3 x P5, and P1 x P2 found as promising hybrids for yield and bean characters. Thus, these hybrids should be advanced in the next breeding program and tested through incorporating other traits.
Serabi Milenial (Serial) Sebagai Inovasi Kue Serabi Unggulan di Desa Borok Toyang Guna Meningkatkan Eksistensi Produk Lokal: Pengabdian Masyarakat
Authors: Adawiah Rabiatun , Raihanun Siti , Sopiati Rohana , Atmanegara Lalu Kusnendar , Saptia Ria Duana , Hadisaputra Saprizal , Junaidi Eka , 'Ardhuha Jannatin , Ashyar Mochammad , Ayub Syahrial
Published: July 2021

Abstrak: Program kegiatan 1000 Wirausaha Baru merupakan salah satu program kegiatan pada KKN New Normal Universitas Mataram yang dilaknasakan selama empat puluh lima hari di Desa Borok Toyang, Sakra Barat. Program ini bertujuan untuk melatih masyarakat di desa tersebut agar dapat mengembangkan kreativitas dan meningkatkan inovasi dalam berwirausaha. Serabi milenial (serial) merupakan salah satu produk lokal di Desa Borok Toyang yang saat ini masih dalam bentuk kue sederhana. Alasan pemilihan produk serial ialah untuk meningkatkan eksistensi produk lokal di semua kalangan termasuk di kalangan generasi milenial. Bentuk pengabdian yang dilakukan yaitu dengan melakukan sosialisasi pada ibu-ibu yang terdaftar dalam Pogram Keluarga Harapan (PKH). Terpilih sebanyak lima orang untuk mengikuti kegiatan sosialisasi di Dusun Dasan Lekong. Metode pembuatan serial masih secara tradisional dengan menggunakan cetakan sederhana. Perbedaan kue serial dengan serabi biasa ada pada tambahan varian warna dan varian toping. Analisis ekonomi usaha serial antara lain: BEP (Break Event Point) dalam unit yaitu 372 biji kue serabi, B/C Ratio yaitu 6,6 dan ROI (Return On Investment) sebanyak 33%. Hasil tersebut menggambarkan bahwa serabi milenial layak dikembangkan sebagai usaha dengan keuntugan besar. Tindak lanjut untuk usaha serial antara lain pembuatan surat izin usaha dagang, pembuatan surat izin BPOM dan pembuatan toko serial.Keywords: P1000WB, Usaha, Serial
English Café: An Initiative to Encourage Undergraduate Learners of Al-Asyah Province to Showcase Their Spoken Proficiency in English
Authors: Jahara Syed Farhat , Abdelrady Abbas Hussein
Published: July 2021

This article advocates that spoken language is learned only when genuine communication and exposure occur, not when it is practiced simply as a set of structures or only when its grammar is learned. This research study demonstrates the possibility of exploring novel approaches to inspire non-native EFL learners in the Al-Qassim region of Saudi Arabia to master communication skills by establishing a linguistic club named English Café to showcase their spoken proficiency. The study sample consisted of undergraduates from level 1 and level 2 from the first year of the B.A. program. The methodology adopted was a descriptive-analytical method using a questionnaire and spoken activities to achieve the desired objectives. One major finding was that participants improved their communicative competence by participating in pronunciation and speaking activities through constant motivation, preferred learning style, self-interest, and willingness to participate naturally with expert guidance initially and constant practice after that.
Stratification of Youth Employment and Departure Abroad with the Purpose of Work: Kazakhstan and Neighboring Countries
Authors: Matzhanova Ingkar , Simtikov Zhomart , Kairbekova Alima , Matzhanova Karlygash
Published: July 2021

Recently, especially given the consequences of COVID-19, external migration processes have become more intense. In Kazakhstan and other neighboring post-Soviet countries, a certain social imbalance is associated with the protracted transition period from the Soviet past to the social order and economy of the future. A widening gap exists between the countries of this region associated with geopolitics; for example, states have to choose the Western or Eastern geopolitical vector of development. Russia has a dramatic effect on the development, economy, and migration of neighboring states with a weaker economy. In this regard, the research focuses on the study of key drivers, factors, and reasons affecting this imbalance in the context of the social strata of Kazakhstan. Based on economic and statistical analysis methods, the study analyzes the current migration situation in Kazakhstan and the CIS region, assesses the level of adaptation of citizens of Kazakhstan to the changing environment and globalization that affects the young population; the mechanism of the influence of regional vectors of geopolitics on Kazakhstan is also determined. Apart from this, the current work examines the propensity of young people to migrate abroad (expressed using an integrated indicator) and provides a regression analysis of factors affecting its level. This allowed assessing the degree of influence of the youth unemployment rate and the general welfare of the country on the inclination to go overseas to find a better job. The paper concludes by arguing that the level of unemployment among the young population has a significant impact on its tendency to migrate. In particular, in Kazakhstan, migration abroad is primarily connected with the possibility to get better career prospects and living conditions provided by the host countries.The research results could be used to manage socio-political and socio-economic issues related to the migration of young people in Kazakhstan and neighboring countries and conduct further research related to analyzing macroeconomic indicators and other factors affecting migration processes.
Personal Well-Being, Mental Resilience and Emotional Intelligence in First- and Second-Generation Druze in the Golan Heights
Authors: Walter Ofra , Siwar Shaalan
Published: July 2021

This study examined personal well-being, mental resilience, and emotional intelligence in the first- and second-generation Druze population in the Golan Heights using qualitative and quantitative methods. One hundred Druze respondents completed four questionnaires (emotional intelligence, mental resilience, demographics, personal well-being), and eight participated in semi-structured interviews. One hypothesis was that the first generation (ages 40-62) who lived through the Six-Day War in 1967 when Israel occupied the Syrian-ruled Golan Heights and the annexation process in 1981, would have lower levels of personal well-being and emotional intelligence than the second generation (ages 25-40) who were born and raised in Israel and did not experience these events. Another hypothesis was that the first generation, having experienced those events, would have higher mental resilience than the second generation.  The findings showed that the second generation had higher levels of personal well-being and emotional intelligence than the first generation. However, mental resilience levels were higher in the second generation than the first. The findings indicated that memories of the stressful historical events and the sense of loyalty to Syria result in an emotional burden that exposes a low level of resilience. The levels of mental resilience predicted emotional intelligence levels and personal well-being, regardless of generational affiliation. This study's findings may be expanded to describe other communities that have undergone similar political upheaval.
Acute mesenteric ischemia in SARS CoV 2: A conventional approach
Authors: Arushi Mohan  , Abhinaya Shekhar  , Brunda MS  , Chaithanya Soma Chetty
Published: July 2021

SARS CoV 2, a novel coronavirus, an airborne virus has been investigated for its inconspicuous prothrombotic states, the mesenteric vessels are one of the many devoured by the virus. Gastrointestinal symptoms may range from a mild gastroenteritis to a grave ischemia indicating a possibility of a severe infection. The hypercoagulability in SARS Cov -2 is possibly related to the hypercoagulable state attributed by the heightened systemic inflammatory response. The interplay of anticoagulants and the immune response is crucial in the management of critical patients , D dimer a fibrin degradation product has demonstrated efficacy in the surveille of coagulability .This case study involved in the scrutiny of a case with the initial presentation of symptoms of lower respiratory tract infection progressing into gastrointestinal symptoms focusses on the medical management of acute mesenteric ischemia in SARS CoV 2, stressing on the importance of early detection and prompt management of the hypercoagulable condition in systems other than the pulmonary system associated with SARS CoV 2. A meticulous analysis of ischemic states in various other organs should be sought in the pandemic.
PERAN GURU PENDIDIKAN AGAMA ISLAM DALAM MENINGKATKAN LITERASI DIGITAL SISWA SEBAGAI KECAKAPAN ABAD 21
Authors: Muflihin Ahmad
Published: July 2021

The purpose of this study is to analyze the amount of Islamic Education (PAI) teachers' efforts and roles, as well as how they should be involved in developing students' digital literacy. This is due to pupils' inadequate digital literacy, which manifests itself as an inability to process information gained via technology, information, and communication devices. In fact, digital literacy is one of the literacy foundations that are included in 21st-century skills. According to data issued by the Ministry of Communication and Information, Indonesia ranks second in cybercrime and the frequency of false information (hoax), making PAI teachers responsible for increasing digital literacy for students on both a moral and professional level. Interviews with various PAI teachers in Semarang are used in this study. The purpose of the interview was to evaluate how far PAI teachers had progressed in enhancing pupils' digital literacy. According to the findings of this study, PAI teachers' efforts are still minimal. The development of information technology as a method and a learning medium has not been optimized. As a result, enhancing digital literacy requires mutual awareness.�Keywords: Islamic Education Teacher, Digital Literacy, 21st Century Skills
Cervical Cancer Self Management Education (CSME) meningkatkan kualitas hidup pasien dengan kanker serviks
Authors: Wuriningsih Apriliani Yulianti , Distinarista Hernandia , Laely Anna Jumatul
Published: July 2021

Kanker serviks merupakan salahsatu penyakit kronis dengan berbagai gejala penyerta selama sepanjang hidup pada penderita. Pasien dengan kanker serviks dapat melakukan manajemen diri terhadap gejala. Beberapa memiliki kemampuan untuk beradaptasi terhadap gejala yang muncul, namun ada juga yang mengungkapkan ketidaksiapan dalam mengelola gejala. Informasi kesehatan sangat penting untuk pasien, berupa mempromosikan rasa kontrol, menurunkan tekanan emosional, mendukung manajemen diri yang efektif, dan menghilangkan gangguan dari aktivitas sehari-hari. Penelitian ini bertujuan untuk mengetahui pengaruh cervical cancer self management education(CSME) terhadap kualitas hidup pasien dengan kanker serviks. Desain penelitian yang digunakan, yaitu eksperimen semu dengan pendekatan pre dan post test pada kelompok kontrol dan intervensi. Besar sampel minimal ditentukan berdasarkan tujuan menguji hipotesis beda dua proporsi kelompok independen dan nilai proporsi efek terapi standar (P1) dengan metode pengambilan sampel menggunakan simple random samplingsejumlah 37 responden. Hasil penelitian menunjukkan bahwa CSME berpengaruh terhadap kualitas hidup pasien dengan kanker serviks dengan nilai p= 0,000.
Love as Embodiment of Gambling (by the Material of F. M. Dostoevsky’s Novel “The Gambler”)
Authors: Zhuneva Ekaterina Sergeevna
Published: July 2021

The purpose of the study is to demonstrate that an individual’s inherently risk-loving nature is able to turn other activities into gambling. The article considers one of the possible forms of manifestation of gambling passion, namely a special form of love. The author uses F. M. Dostoevsky’s novel “The Gambler” as the research material. The study is novel in that it considers relationships between the main characters of the novel not as a cause of gambling addiction but as a consequence of the Gambler’s penchant for risk taking. As a result, it is proved that the Gambler has an immanent penchant for risk taking, which can manifest itself not only through gambling but also through other life processes.
Economic Life of Sevastopol during the Second Defence (1941-1942)
Authors: Baranov Alexey Gennadievich , Garmashova Elena Petrovna , Dmitrieva Viktoria Viktorovna , Mitus Aleksandr Aleksandrovich
Published: July 2021

The purpose of the research is to identify the features characterising economic activities and patterns of historical and economic development in Sevastopol during the second defence of the city amid the Great Patriotic War. Scientific novelty of the research lies in undertaking an interdisciplinary examination of Sevastopol economic life during the war period with the involvement of methods of historical and economic sciences. As a result, the researchers have determined final results and examined the process of carrying out the main, top priority economic tasks that were dealt with by Sevastopol city authorities and the military command during the second defence of the city. In particular, the authors have studied regulatory and legal documentation, as directed by which the urban economy was adapted to wartime needs, production levels, conditions and mode of operation of the city enterprises, issues of providing medical care in the wartime setting.
Human Dignity Notion: Origins, Meaning and Modern Interpretation
Authors: Sycheva Tatiana Mikhailovna
Published: July 2021

The purpose of the study is to provide rationale for defining role of historical sources in formation of modern meaning and significance of the human dignity notion. Despite the fact that there are many interpretations of the dignity notion and that its content has virtually undergone radical transformation, according to the author, essence of modern understanding of dignity still amounts to the meanings and significance that were formulated in the process of philosophical and ethical thought development. The study is novel in that it provides rationale for substantive role of historical sources in formation of modern meaning of the human dignity notion, which is of universal importance, and resolves the problems generated by rapid scientific and technological advancement of the society. As a result, the researcher has come to the conclusion that modern understanding of human dignity, which is considered as a universal value possessing cultural and geographic specificity, includes in its essential content the meanings and significance that have been formulated in the process of historical development of philosophical thought and is a basis of the equal dignity concept.
Verbal Text as Compositional Material in Georges Aperghis’s Works
Authors: Yakovleva Tatiana Olegovna
Published: July 2021

The purpose of the study is to characterise specific nature of Georges Aperghis’s work with the verbal text in chamber compositions. Aperghis systematically turns to phonemes and words in different genres: in chamber music, musical theatre. The composer uses prosodic elements in instrumental lines, creates allusions to rhetorical utterances and percussive elements in speech. Scientific novelty lies in identifying the main principles of Aperghis’s work with the text. As a result, it is determined that the author uses structural components of the text in rhetorical, percussive and word-painting compositional elements.
Historical and Architectural Features of the Ozono-Chepetsky Orphanage in Vyatka Province in the Early XX Century
Authors: Ryzhkova Natalia Viktorovna
Published: July 2021

The purpose of the study is to identify historical and architectural features of the Ozono-Chepetsky Orphanage founded in the early XX century. This is one of the first orphan’s homes of the so-called rural type in Vyatka Province. The article is novel in that it is the first to analyse historical and architectural features of the orphanage in the course of a comprehensive study and on the basis of published and unpublished sources. As a result of the work, general and specific trends in historical development of the Ozono-Chepetsky Orphanage and in evolution of its architectural appearance were determined.
Scientific Community of the Soviet Historians during the Great Patriotic War (1941-1945)
Authors: Smirnitskiy Aleksandr Evgenievich , Volkova Anastasia
Published: July 2021

The purpose of the research is to determine the main areas of the activities undertaken by the Soviet historians during the Great Patriotic War. The article considers research activities, agitation and propaganda work, participation in activities of state and public organisations in the context of social conditions of the Great Patriotic War. It is shown that the Soviet historians’ activities during the Great Patriotic War were not limited to the purely academic kind. They were strongly involved in information war against fascism by means of history. Scientific novelty of the paper lies in taking a comprehensive approach to studying the Soviet historians’ activities during the Great Patriotic War in the context of social development of that time. As a result, the researchers have identified the main areas of the activities undertaken by the Soviet historians during the Great Patriotic War and their contribution to victory over fascism.
Communicative Space of City: Challenges and Responses of Modernity
Authors: Tuliganova Irina Valeryevna
Published: July 2021

The purpose of the study is to determine the features of the communicative space of the city at the present time. The article identifies the qualitatively new ways of organising communication in megacities in the setting of informatisation and digitalisation processes, as well as during the spread of the COVID-19 pandemic as a global social challenge. Scientific novelty of the study lies in carrying out a comprehensive analysis of the impact that the COVID-19 pandemic is having on communication in the city. As a result, it is shown that significant advancements in information and digital technologies caused by the pandemic have both a positive and a negative impact on building social interactions in the city space.
Formation of the Venetian Folk Barcarole: Genre Origins and Typology
Authors: Nosoreva Elena Valentinovna
Published: July 2021

The purpose of the research is to consider historical and theoretical aspects of the previously unexplored Venetian folk barcarole, to study origins of its formation, etymology of meanings of the genre that is unique in its musical embodiment of the theme “man and nature”. The article is novel in that it is the first to create a typology of the folk barcarole on the basis of the Russian theory of music genres. Foreign works previously unknown in the Russian musicology are translated by the author and introduced into scientific use. Comparing the barcarole and examples of functional music of Western Europe, the researcher determines their commonalities and differences. The findings amount to identification of the genre structural and semantic complex, which then becomes an invariant for composers’ works.