bluuebunny/crossref_metadata_2025 huggingface dataset:
Search for Eco-friendly Alternatives Refrigerants in Vapor Compression Refrigeration Systems for Reducing Global Warming and Ozone Depletion
Authors: Mishra R. S.
Published: January 2023

In the Make India and Green India Program, the use of eco-friendly refrigerants is well demonstrated due to global warming and ozone depletion. This paper highlights the use of R-290 refrigerant is the best alternative and second alternative is R600a. and third is R-152a. Due to flammable nature of these eco-friendly refrigerants, these refrigerants can only be used by using safety measures, otherwise R134a and R410a and R404a are easily available in the markets can be used. The performance of R134a gives better than using R410a and R404a, however for larger Industrial applications R 717 and R744 can be used. Even in mixing of nano-particles mixed with R718 in the secondary circuit and R1234yf for low temperature applications gives better first law and second law performance as compared to R134arefrigerant To replace, R134a, R1234yf (of zero ODP and 4 GWP) and R1234ze (GWP=6, and Zero ODP) are recommended, although these refrigerants gives 5 to 10% less performance than using R134a. Although the performance of R134a is better than R134a using nano particles mixing in R718 but R1234ze can replace R134a for higher temperature applications. The best first law and second law performances have been found using copper nano materials mixed with R718 in secondary evaporator circuit as compared to TiO2 nano particles
Investigation of Mechanical Properties of Composite Material Reinforced by Aluminum-Fibers
Authors: Kumara Vipin , Kambojb Anil Kumar , Srivastavaa Prachee
Published: January 2023

A composite material is made from two or more constituent materials with significantly different physical or chemical properties that, when combined, produce a material with characteristics different from the individual components. The individual components remain separate and distinct within the finished structure. The new material may be preferred for many reasons. More recently, researchers have also begun to actively include sensing, actuation, computation and communication.
In this work the mechanical properties of aluminum, glass fiber and synthetic fiber and their composite with aluminum were evaluated with reference to ASTM D638-02 a. During the tensile load, the maximum strain was obtained in synthetic fiber whereas maximum stress was obtained in glass fiber- synthetic fiber composite. Composite material has shown an improvement of mechanical properties when compared with individual materials.
Design and Development of Smart Landline Using 3D Printing Technique
Authors: Haleem Abid , Khan Angveen , Javaid Mohd
Published: January 2023

In today’s workplace be it office or home, telephones are indispensable entity, since telecommunication is a crucial and growing part of any work. However, using a traditional telephone handset often involves strenuous movement and unnatural postures such as cradling the handset between neck and shoulder, and having to stretch to reach for things. Research in office workplace ergonomics clearly indicates that use of a classic telephone handset by office workers is a major source of work-related neck and back pain.
Spending prolonged periods of time on the telephone can often lead to musculoskeletal disorder like chronic neck, shoulder and upper back pain disorders. While these may seem as unimportant issues but in the long run they can potentially permanent damage to the tendons, muscles, tissues, nerves and supporting structure. Ergonomically poorly designed phone contributes to musculoskeletal symptoms.
The paper at hand focuses on regeneration or modification of hand held equipment (in this case: a landline phone’s receiver) using Reverse Engineering. The regeneration is made taking into consideration the Ergonomic factors such as grip comfort and wrist strain due to prolonged usage. The modifications were done so as to incorporate major technological changes, such as converting the obsolete landline phone into a smart landline phone. After making all changes, the new product was manufactured using 3D printing machine ProJet460 installed at JMI, New Delhi. The prototype was then compared to the original model on dimensional accuracy, grip comfort and wrist strain and its advantages, disadvantages and limitations were noted.
Skill Development in Solid Waste Management
Authors: Gupta Shubham , Mishra R. S.
Published: January 2023

To have fast and sustainable growth power demand-supply gap can be linked only by consuming and spreading of renewable energy sources such as Solar, Wind, Biomass, Small Hydro, etc. Fossil fuels are fast depleting and pose an intolerable import bill while adding to the overall pollution. Municipal Solid Waste (MSW) has high potential of generating energy by utilizing various techniques. Training programmes are needed across India for development of skill, knowledge for effective and efficient utilization of MSW to meet rising energy demands in India.
Clinical Trial in India: a Boon or Bane
Authors: . Divya
Published: January 2023

The study of Pharmacodynamic and Pharmacokinetic characteristics of new chemical entity (NCE), device on a specific kind of patient, different dose treatments, therapies and surgical procedures to observe behavioral changes due to drug, before making it publicly available. It also examines safety and efficacy of already marketed medication or device for a new indication. These studies help in ensuring the effectiveness of new medicine or device in comparison with the old ones. India emerged as the most suitable country in the world for clinical trial during 2006 and 2010. Many reasons and facilities attracted outsiders for clinical trial in India. Those were mainly big population, availability of new patients for diverse treatment, low cost of drug experimentation and speedy approval. This was a big advantage for our country in terms of financial and scientific gain especially for individual who could not afford for medicines because of poverty. However, unethical practices, noncompliance of regulatory guidelines and protocol, conduction of trials without the approval of ethics committee were some of the discrepancies which converted it from boon to bane. There were several reports of exploitation of the poor and illiterate Indians. It was assumed that they were treated as guinea pigs for clinical trials. Increasing reports of trial participant fatalities aroused the need of robust vigilance. In 2013, the Supreme Court of India took serious cognizance on the PIL filed by Non-Government Organizations. All trials of new drugs were subsequently put on hold and passed strict regulation of three tier screening of their clinical trial documents before supplying drugs to the market. DCGI and ethics committee are the supervisory body of clinical trial to ensure safety, efficacy and quality of trial.
Phyto chemistry, Pharmacology and Nutraceutical Potential of Enset (Ensete ventricosum): A Review
Authors: Tesfaye Azene , Guaide Awoke , Melese Meseretu
Published: January 2023

Enset (Ensete ventricosum) belongs to family Musaceae is a plant native to Ethiopia, it is often called false banana for its close resemblance to banana plant. Enset is drought-tolerant, multi-purpose crop which has been part of a sustainable cropping system with high agro-biodiversity in Ethiopia. It could improve food and health security in the country especially where other options is low. Enset plant contains starch and other minor/trace elements which contributes in its nutraceutical applications. Starch is major constituents of the plant and play crucial role in pharmaceutical activities including: Tablet binder and disintegrant, Pharmaceutical gelling agent, Sustained release agent. Nutrional values and major food products of enset, namely Koch, amicho and bulla along with medicinal values encompasses; anti-microbial, anti-nematodal diseases of humans, expel of placenta, healing bone fracture are some nutraceutical applications of enset.
A Stochastic Model for HIV Patients Using Three Parameters Exponential Weibull Distribution
Authors: . Bharathidass , Pandiyan Sathiyamoorthy , . Lognathan
Published: January 2023

The present research study attempts to developed a mathematical model for calculating expected time of break down point/servo conversion threshold level using exponential weibull distribution which would helps reduce the spread of HIV from once person to another by models such as needle sharing among drug abusers, prostitutes, homosexuals and blood transfusion and so as such that more accurate data could be obtained about the accurate data could be obtained about the given population of study, thus decreasing the spread as well as pointing out the mutual independence of inter arrival time between successive contacts sequence damage and threshold.
GSM Based Electronics –Notice Board
Authors: Chauhan Prerana , Agarwal Shikhar , Singh Hem Kumar , Saini Ashish
Published: January 2023

In this technical paper explains how a reliable and an authentic wireless communication could be easily developed between a mobile phone and microcontroller using GSM (Global System for Mobile Communication) MODEM (Modulator-Demodulator). This technical paper explains GSM based e-notice board which can be widely used for multitude of applications including educational sector, traffic control, banks, public advertisements, stoke exchanges etc. Moreover we can also learn as well as modify some of the common applications of GSM MODEM as per the requirements and needs of the user. Here we will learn the hardware behind the picture. In addition to this I will tell you how to upgrade the software resulting low NRE (Non-Recurring Engineering) cost as well as low time-to-market. This technical paper plays a vital role in the state-of-the-art scenario where market window is relentlessly shrinking and really need pocket-friendly and authentic products.
Design and Analysis of DC-DC Boost Converter
Authors: Rai J. N. , Gupta Nikhil , Bansal Prashant
Published: January 2023

This paper demonstrates the design of a working prototype of 5-12V DC-DC Boost Converter. The boost converter circuit is designed using MOSFET, Resistor, Capacitor, Inductor and Diode. The key principle that drives the boost converter is the tendency of an inductor to resist changes in current. Inductor is designed using ferrite pot core and windings. This paper briefly reviews the technology used in switched mode power supplies for DC to DC conversion for transferring energy from input to output. Simulation studies are performed using MATLAB tool to validate the proposed scheme as well as hardware practical results.
Comparative Study of Romantic and Modern Poetry
Authors: Narain Prakash
Published: January 2023

Romantic and Modern Ages are well known for the dominance of poetry. A comparative study with critical approach of the poetry composed during both the ages. It is difficult to pinpoint the exact start of the romantic movement, as its beginning can be traced to many events of the time: a surge of interest in folklore in the early to mid-nineteenth century with the work of the brothers Grimm, reactions against neoclassicism and the Augustan poets in England, and political events and uprisings that fostered nationalistic pride.
Optimization of Helical Gear Design Using Genetic Algorithm for Center Distance
Authors: Gopal Ram , Suman Rajiv , Jadoun R.S.
Published: January 2023

The helical gears are employed to transmit motion between parallel shafts. These gears can also be used for transmitting motion between non-parallel, non-intersecting shafts. Helical gears are similar to spur gears except that the gears teeth are at an angle with the axis of the gears. In a genetic algorithm, populations of individuals, which are potential solutions to the optimization problem, undergo a sequence of unary and higher order transformations (also known as mutations and crossovers respectively). Genetic algorithms are being widely used for optimization, search and neural network synthesis. A lot of work has been conducted using genetic algorithm for different engineering problems related to scheduling and process planning in industrial engineering, network optimization in computer engineering. The work dissertation deals with the optimization of helical gear sets using genetic algorithm. Attention is focused on reducing the center to center distance of gear set subjected to constraints on bending stress, contact stress and involute interference.
Mechanical Properties of 7075 Aluminium Matrix Composites Reinforced by Nanometric Silicon Carbide Particulates
Authors: Sultan Samar , Bisht Shweta , Arya Shweta
Published: January 2023

Aluminum Matrix composites (AMCs) are known as light weight and high-strength materials with their potential application in areas such as aerospace, automobile, defence, engineering and other industries. AMCs have the advantage to significantly reduce the overall weight of the vehicles and aircraft while maintaining their structural strength. Reinforcement of micron or nano-sized range particles with aluminium matrix yields improved mechanical and physical properties in composite materials. The strength of Al matrix composites will be improved about 20% with decreasing reinforcement particle size from micrometric scale to nanometric scale. In this study, Al7075 alloy and nano SiC composites have been fabricated by Electromagnetic stir casting process combined with mechanical stirring. Different weight % of nano SiC particles (0.5, 1, 1.5, and 2 wt%) were used for synthesis of composites. Certain test methods scanning electron microscopy (SEM) and X-Ray diffraction (XRD) are used to examine the microstructure along with the measurement of impact strength of the nano composite. SEM microstructure shows SiC particles are fairly infused into the matrix alloy with agglomeration and porosity at some places. X-Ray Diffraction (XRD) analysis acknowledged that no unknown crystalline elements are present in the composites while mixing reinforcement with Al alloy matrix. The results impact strength shows that impact strength decreases with respect to the base metal because of brittle nature of reinforcement.
Quality Function Deployment in India: A Review
Authors: Shukla M. K. , Chauhan B. S.
Published: January 2023

The term Quality Function Deployment (QFD) plays a very crucial and important role in the manufacturing sector not only from theoretical perspective but also from managerial perspective. QFD is a system for designing a product or service based on customer demands that involves all members of the producer or supplier organization. In the present scenario, automobiles are the most effective medium of transportation. QFD is a four phase model, which includes the house of quality (HOQ), parts deployment,, process planning and production planning. Among the various stages, the HOQ is most commonly used stage and its aim is to reflect customer desires (E.I.). For this, the organization conducts surveys, the research, trend research; Planning of the product also involves study of different territorial and climatic condition and other such factors. Through this, the organization will get an idea about the views and choices of their customers, opinions about the various components of the product, common complaints, etc. It is through these set of activities that the organization is able to identify specific product quality features. Apart from these error identifying techniques, a method known as Failure Mode and Effects Analysis (FMEA) is developed for preventing both part and process type failures. This research work shows how Quality Function Deployment is helpful in improving the development process with a special focus on needs of customer i.e. what features are needed by customer while using and expectations.
Smart Application for Food Donation Using Cloud Computing
Authors: Agrawal Sanjay , Deshmukh Sarjerao , Rawade Rohit , Desai Mayuri
Published: January 2023

Food is necessary for everyday life. The task of food donation is to donate food from various donors and store the data in the database to donate the food to the needy people or orphanage. The problem is not the insufficient number of donors, but finding willing donors at the right time. We want to build a network for peoples who can help each other when peoples are hungry. This application time updates the information regarding the donors where the administrator accesses the whole information about food donation system. A donor, needy people or orphanage will be prompted to enter an individual detail, like name, phone number, and address on the cloud. Food donation Application provides a list of food donors in your area. Only a registered person with a willingness to donate food will be able to access the service. In this application, we are using a GPS technology that will be used to trace the way of donors.
Engineering Interventions for Technological Advancements in Dairy Industry
Authors: Chauhan I. A. , Jana Atanu , Mackwana A. K. , Bhadania A. G.
Published: January 2023

India today is already the worlds’ largest producer of milk but the country is not a dominant force in the world market of milk and milk products. The growth potential of Indian Dairy Industry is enormous and challenges exist in improving the efficiency level and quality in complete chain of milk processing at every stage. The production of quality milk and milk products begins on the farm and continues through further handling, processing, packaging and distribution. One of the most important tasks amongst the quality control is to control and follow up regularly the fulfilment of quality standards at every stage of process flow in order to guarantee the best possible quality of end products through technological advancements. Engineering interventions have vital role to play in achieving this objective. Milk production, reception, processing, packaging, quality assurance, storage and distribution have been selected for engineering interventions for technological advancement in dairy industry.
Design and Fabrication of Low Cost Crop Cutting Machine
Authors: Singh Abhishek Pratap , Jain Anuj Kumar , Vij Mohit , Sood Siddharth
Published: January 2023

The problem faced by farmers who work on small fields while harvesting crops as it takes a lot of time, labor and effort to cut the crops manually. Although Harvesting machines are already available in the market but these are quite large and costly. Since farmers with small lands have no such large usage and also harvesting is done only twice or thrice in a year, it becomes difficult for small farmers to afford such kind of a machine. So, it becomes essential to make a portable and cost efficient semi or fully automatic crop cutting machine. To achieve this aim, a lot of ground research has been done in this project wherein various farmers of a village near Gurgaon were met and their problems were understood. Based on all the findings, a design for a crop cutting machine has been developed which is expected to help small scale farmer’s big time. A prototype has been developed which is easy to operate and can be used for efficient and effortless harvesting of fodder crops. The model so constructed, can be used by small scale farmers for increasing their profits by decreasing labor and machinery cost. This model will offer a superior and cheap technique to decrease labor and endeavors required in collecting crops.
Influences of Alloying Element on the Mechanical Properties of Aluminum Alloy- A Review
Authors: Yadav Abhishek , Panchal Jitender
Published: January 2023

The unique combinations of properties provided by aluminum and its alloys make aluminum one of the most versatile, economical, and attractive metallic materials for a broad range of uses from soft, highly ductile wrapping foil to the most demanding engineering applications. Aluminum alloys are second only to steels in use as structural metals. In last decade there has been a rapid increase in the utilization of aluminum generally designed for low weight and low costs, which yields the use of hydrodynamic journal bearing in a large number alloy in automobile industries due to high specific strength, high wear resistance, low density, and low coefficient of thermal expansion.
Influence of radial clearance on the static performance of hydrodynamic journal bearing system
Authors: Awasthi R. K. , Bitta Harpreet Singh
Published: January 2023

The present work aims to analytically study the clearance effect on hydrodynamic journal bearing system’s static performance. The mathematical model of hydrodynamic lubrication i.e. the non-dimensional Reynolds equation is solved with the help of FEM formulation using Garlerkin’s approach along with appropriate boundary conditions. A positive pressure zone, which is unknown priori is established using Reynolds boundary condition through iteratively. The study uses a non-dimensional clearance parameter and its influence on fluid-film pressure and static performance parameters of hydrodynamic journal bearing is studied. The static performance parameters include maximum pressure, load carrying capacity, attitude angle, and coefficient of fluid-film friction etc. The simulated results indicate that the low value of clearance is often a better option which however is limited by surface asperities. The results of the study are useful to the bearing designer from the view point of optimal selection of clearance parameter on the bases of maximizing bearing load and minimizing friction force.
Particle Swarm Optimization for the Optimal Wind–Thermal Coordination
Authors: Saravanan R , Subramanian S. , Dharmalingam V. , Ganesan S.
Published: January 2023

The Economic Dispatch is an important optimization task in power system. Thermal power plants are the major electrical energy producers. Need for renewable energy occurs due to the extinction of fossil fuels. Hence, it is necessary to operate these renewable plants with the thermal plants. In India, especially in Tamil N adu, Wind is the renewable plant which is widely available. The problem with the wind plant is its unpredictability. Hence, better wind thermal coordination economic dispatch method is necessary to integrate wind power reliably and efficiently. In this paper, Particle swarm optimization (PSO) technique is utilized to coordinate the wind and thermal generation dispatch and to minimize the total production cost. Ten units of thermal system incorporating wind power plant is utilized for numerical simulation. Different simulations with and without wind power production are simulated. Simulation result shows the effectiveness of wind power generation in reducing total fuel cost when compared with the genetic algorithm.
An innovative approach to modeling the benefits of supply chain collaboration by using interpretive structural modeling
Authors: Singh Harjit , Garg R. K. , Sachdeva Anish
Published: January 2023

Supply chain collaboration means the firms within the supply chain collaborate with each other to work together and gain mutual objective by sharing of ideas, information, knowledge, risks and rewards among all supply chain partners. Facing uncertainty in supply and demand, firms have strived to achieve greater collaboration to leverage the resources and knowledge among supply chain partners. Supply chain collaborative firms gain more benefits by satisfying customer’s requirements as compared with firms those work individually and having no collaborative relation within partners of supply chain. Therefore there must be a proper understanding of the collaboration and its application within supply chain. One of the best methods to understand and create interest in collaboration is the understanding of the benefits which are come out from supply chain collaboration. Therefore in this study we indentify various benefits of supply chain collaboration from literature and design a relation between these benefits with each others, so those decision makers understand these benefits and proceed towards collaborative supply chain. In this study ISM methodology is used for modeling the benefits and MICMAC analysis is used for classifying these benefits according to driving and dependence power. The study is helpful for supply chain decision makers to implement collaboration in supply chain.
Open Innovation adoption strategy enhancing performances in Malaysian SMEs
Authors: Annamalah Sanmugam , Raman Murali , Marthandan Govindan , Logeswaran Aravindan Kalisri
Published: January 2023

Open innovation model is best suited to SMEs as it complements internal RD in enhancing performances and cost effectiveness through sustaining or gaining competitive advantage. This conceptual framework looks into the aspect of behavioral and cost to determine the adoption level. Aspect of study includes organizational citizenship behavior, managerial ties, organizational culture, transactional costs and appropriability regime to determine the relationship between these factors in manufacturing environment. OCB moots employees’ commitment as they are considered to be the most influential people in any organizations who are able to support innovations. The theories utilized in this research are drawn from multiple theoretical perspectives from Open Innovation theory, Social Exchange Theory and Actor Network theory. Collaboration among all the concerned external parties is crucial for SMEs in supporting innovation. External parties include external firms, R D organizations and government officials. Organizational culture affects the technology adoption through work practices as well as productivity and therefore management need to inculcate culture that promotes collaborations and supports to expedite open innovation. However the adverse culture may impact adoption negatively. External technology open doors for free riders and therefore protection mechanism must be enhanced through appropriability. Appropriability mechanism is important in protecting the innovative ideas from external parties through intellectual property rights especially in manufacturing sector as it impacts the innovation capabilities and revenues. The aim of the research is to evaluate the open innovation approach for SMEs with respect to the performances and sustaining the innovative development of productions in the long term. Quantitative techniques by adopting Partial Least Squares regression (PLS) utilized to explore the fundamental relationships and analyze linear regression model by projecting the predicted variables and the observable variables. The findings of this study will help SMEs to develop new tools and technologies that are driven by open innovation concept. It also broadens the body of knowledge of open innovation especially in providing new evidence on how performances can be achieved in the long run. From theoretical aspect, this study contributes by exploring the dimensions of various behaviors and providing guidelines to SMEs the behaviors that is positively associated to Open Innovation adoption.
Les brachiopods du Jurassicque supérieur des Monts de Tiaret (Algérie du Nord)
Authors: Tchoumatchenco Platon
Published: January 2023

The brachiopods came from two palaeogeographic areas – from the shelf area of the Tlemcenian Domain (High Plains) and from the slope of the Tellian Basin (Tellian Domain). From the Tlemcenian Domain (near the Oued Mina cascade) from the Oxfordian came Somalirhynchia moravica, Septaliphoria arduenesis, Moeschia cf. zieteni, Sellithyris subsella, Trigonellina trimedia, and Terebratulina sp. From the slope of the Tellian Basin (massif du Bou Rheddou and Djebel Bechtout) came Nucleata nucleata, Lacunosella selliformis (Middle and Upper Oxfordian and the very base of the Kimmeridgian), Monticlarella czenstochaviensis, M. strioplicata, M. striocincta, Lacunosella bourheddouensis, Nucleata nucleata (Upper Kimmeridgian), Tiarethyris tiaretitensis, T. rectimarginata, Moeschia engeli krzyzanovici, Monticlarella striocincta, M. ctrioplicata, M. czenstochaviensis, Nucleata nucleata (Lower Titonian) and Zeillerina slaimensis, Moeschia engeli krzyzanovici, Nucleata euthymi, Thurmanella acuticosta (upper part of the Lower Tithonian). In the basin sediments of Grand Pic de l’Ouarsenis was found only Pygope sp. ind.
The Influence of Need for Achievement and Self Efficacy on Student Entrepreneurship Intention
Authors: Damayanti Susi
Published: January 2023

Basically, students' entrepreneurial intentions have varying views among students, besides that the recognition and desire of a person in determining his future also affects the willingness of students to decide to focus on pursuing the world of entrepreneurship which does indicate uncertainty in obtaining profits or losses. The purpose of this study was to be able to determine whether there was an influence between need for achievement and self-efficacy on student entrepreneurial intentions. The method used to expedite the research process is a quantitative method, the analysis technique used is multiple regression analysis with the sampling technique used, namely saturated sampling for class 2G students of the Management Study Program, Nusantara University PGRI Kediri class of 2021, a total of 42 students. The research results obtained include: 1) 96% of students agree and strongly agree that the need for achievement variable shows an influence on entrepreneurial intentions; 2) 86% of students agreed and strongly agreed that the self-efficacy variable showed an influence on entrepreneurial intentions; 3) From the partial results of the multiple regression analysis test, it can be seen that the need for achievement variable shows no significant influence, but the self-efficacy variable shows a significant influence; 4) From the simultaneous multiple regression analysis test results, it can be seen that all variables show a significant influence, between the need for achievement and self-efficacy variables on entrepreneurial intention.

Keywords: Need for Achievement, Self Efficacy, Entrepreneurial Intention
Comparison of different supervised machine learning algorithms for bead geometry prediction in GMAW process
Authors: Saeheaw Teerapun
Published: January 2023

Gas Metal Arc Welding (GMAW) is an extensively implemented arc welding process through the control of input process parameters and the metal from the filler wire. Despite its popular use in various industries, the complex interrelationship between the actual bead and the varying welding parameters makes it challenging to predict appropriate bead geometries via mathematical modeling in a continually changing welding process. In this study, the Regression Learner App was used to compare the performance of supervised Machine Learning (ML) predictive models comprising the Linear Regression (LR), Regression Tree (RT), Support Vector Machine (SVM), Ensembles of Tree (ET), Gaussian Process Regression (GPR), and Artificial Neural Network (ANN) using GMAW dataset. The dataset was scaled and normalized at a range of -1 to +1 to facilitate the visualization of the variation effect. The wire feed speed, voltage, weld velocity, unmelted wire length, and melted wire volume were considered as the input parameters to predict the bead geometry. In addition, the five-fold cross-validation was employed to avoid overfitting and poor generalization. Finally, statistical indicators, namely the Coefficient of Determination (R2), Root Mean Squared Error (RMSE), and Mean Absolute Error (MAE), were performed on all developed models to evaluate their performance. Thus, the fine tree and ANN models achieved the highest prediction accuracies of 88–91%, signifying their potential use in future research. In short, the present study demonstrated the performance of various supervised ML algorithms for bead geometry prediction, which would assist the selection of appropriately supervised ML algorithms in future studies.
Formulation and characterization of Sauropus androgynous (L) Merr leaf extract Gel in Combination with CMC-Na and Carbopol 940 Using DPPH Method
Authors: Yuliani Ni Nyoman , Sambara Jefrin , Poddar Sandeep , Das Urmisha
Published: January 2023

Introduction: Katuk Leaf (Sauropus androgynus L. Merr.) from Kupang, East Nusa Tenggara, Indonesia is a type of plant that contains chalcone which is used as an antioxidant. This study aims to formulate a gel preparation from Katuk Leaf extract using various concentrations of CMC-Na and carbopol 940, to see the stability of the physical properties of the Katuk leaf extract gel Sauropus androgynus (L.) Merr. Methods: Katuk Leaf Extract was obtained by percolation method using 70% ethanol as solvent. The gels were made in formulas 1, 2, 3, 4, and 5 with a concentration of CMC-Na and carbopol 940 at 0:10; 1:9; 2:8; 9:1; 10:0 ratio. Antioxidant activity was tested with DPPH, observed for its physical stability including organoleptic, homogeneity, viscosity, pH dispersion, adhesion, and gel stability using the process of freeze thaw action. Results: The results showed that the concentration of carbopol 940 increased viscosity and adhesion and decreased dispersion and pH, while CMC-Na increased dispersion and pH and decreased viscosity and adhesion in the physical properties of the Katuk Leaf extract gel. Test results with IC50 extracts of Katuk Leaves at 73.815 ppm, showed that the formula 3 with a concentration of carbopol 940 and CMC-Na at 2: 8 percent by ratio, is a gel with antioxidant activity being most effective with the value of the IC50 100.814. Conclusion:So, it can be concluded that the stability of the physical properties of the gel shows the formula 3 with concentration carbopol 940 and CMC-Na at 2%: 8% gel with the best stability of physical properties.
Sero-characterization of intestinal and extra-intestinal Escherichia coli (E. coli) isolates from different geographical locations in India
Authors: Kumar Gulshan , Kumar Yashwant , Kumar Gaurav , Kumar Tahlan Ajay
Published: January 2023

Serotyping is the most widely used epidemiological marker to characterize pathogenic E. coli. Pathogenic E. coli is diverse as different serotypes are known to be prevalent in different area. Certain serotypes are known to be closely associated with pathotypes especially among diarrheagenic E. coli. Analysis of E. coli serotypes prevalence and its distribution pattern in different geographical area is important from better understanding its epidemiology and better control and management of E. coli diarrhea and non-intestinal infections. Present study was carried out to study prevalence of various “O”serogroups in clinical E. coli isolates in India and its distribution in different geographical locations of the country. A total of 783 clinical isolates suspected to be E. coli comprising of 437 Intestinal (human diarrheal) and 346 extra-intestinal isolates (human UTI) were biotyped using conventional Biotyping method to confirm isolates as E. coli. A total 534 confirmed E. coli isolates were sero-typed using specific anti E. coli “O” antiserum by micro titer plate agglutination assay. The 534 E. coli isolates were found to be clustered over 36 different groups. O8, O11, O22, O126, O88, O83, O35, O7, O149 and O141 being the most frequently detected “O” serogroups. Serogroup O157 was also detected in only seven isolates. Big six serotypes were not detected. This study indicates that diverse E. coli serotypes are in circulation in the country. With very low frequency of serogroup O157 frequently associated with EHEC/STEC.
Potential matrix metalloproteinase-9 inhibitor of aurone compound isolated from Sterculia quadrifida leaves: In-vitro and in-silico studies
Authors: Rollando Rollando , Warsito Warsito , Masruri Masruri , Widodo Nashi
Published: January 2023

In our previous study, aurone compound were found in the n-butanol fraction of Sterculia quadrifida leaves. The aurone compound (compound 1) had high cytotoxic activity in cell lines with IC50 values of 4.05, 12.53, 15.38, and 25.91 μg/mL in 4T1, MCF7, MDA-MB-435, T47D, respectively. In this study, we performed the MMP-9 enzyme inhibition test with FRET assay, and to deepen the mechanism of action of the compounds use molecular docking and molecular dynamics. The results showed that compound 1 had the MMP-9 enzyme inhibition of 91.23% and IC50 48.27%. Furthermore, molecular docking and molecular dynamic simulation suggest compound 1 interacts firmly and stably at the enzyme catalytic site. In conclusion, this study can provide important information on the development of herbal medicines that are potentially cancer drugs.
Development and Evaluation of Essential Oil-based Lozenges using Menthol and Eucalyptus and in vitro Evaluation of their Antimicrobial activity in S.aureus and E.coli
Authors: Ranjan Sahoo Manas , Srinivasan Umashankar Marakanam , Raghava Varier Ramesh
Published: January 2023

The throat lozenegs are most commonly used first line of treatment for relief of various throat infections. The most common ingredient used in the lozenegs are various herbal extracts and essential oil having local action of throat area. in the present studies a essential oil based lozenges were prepared using eucalyptus oil and menthol as active ingredient. Antibacterial activity was evaluated for menthol and eucalyptus oil against human pathogens E.coli and S.aureus. both the sugar based and sugar free base was used to develop two types of lozenges formulation. Quality parameters were evaluated for lozenges formulations such as hardness, friability, dissolving time, and moisture content. Compatibility study was carried out using thin layer chromatography and gas chromatography analysis. The eucalyptus oil and menthol displayed moderate antibacterial activity against E.coli and S.aureus. The lozenges were found to be having satisfactory quality parameters. GC and TLC analysis was found to be a suitable method for identification of menthol and eucalyptus oil in the lozenges. TLC was found to be a simple, quick and simple technique for rapid identification of the essential oil and to confirm the batch-to-batch consistency. 1H-NMR and 13C-NMR was found to be useful tool for rapid identification of essential oils on basis of diagonostic peaks. Overall this study can be used for standard methods for quality control of the essential lozeneges formulation for the new formulation and product available in the market as well.
On the Minimal Annulus of Triangles and Parallelograms
Authors: Vassallo Salvatore
Published: January 2023

Sharp upper and lower bounds for the isoperimetric deficit of triangles or parallelograms with the minimal annulus of radii $R$ and $r$ are given.
Short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients: a case series of 121 brain tumor patients
Authors: Silverstein Justin
Published: January 2023

Join Dr. Randy D'Amico and Dr. Jason Sheehan of the Journal of Neuro-Oncology as they sit down with neurophysiologist Dr. Justin Silverstein from Lenox Hill Hospital to discuss the short and long-term prognostic value of intraoperative motor evoked potentials in brain tumor patients.
Experimentalism and Sociology: From Crisis to Experience
Authors: Knorr-Cetina Karin , Marres Noortje , Rheinberger Hans-Jörg , Bogusz Tanja
Published: January 2023

Has society become a “real-world laboratory”? Tanja Bogusz asks this question in her book as she traces back the experimentalist approach from early American pragmatism to contemporary world society. She recommends that sociology, as a discipline, transform from a science of crisis towards an experimental science of experience, focusing on heterogeneous cooperation
to overcome the epistemic disparities of our time. The speakers will discuss the book’s core ideas, as well as its impact on current global challenges.

Springer, in association with the Center for Sustainable Society (CSS), University of Hamburg, is delighted to invite you to join the author and the internationally renowned panellists at this online event. Professor Stefan Aykut, Director, CSS, will begin the event with a short introduction on the center's programs.
African American Abolitionists in Chester County: Finding New Stories
Authors: Sullivan Michele
Published: January 2023

Historians have traditionally recounted the history of the Underground Railroad in Chester County and elsewhere in Pennsylvania as the work of heroic Quakers. When African Americans are included, for example, in R. C. Smedley’s History of the Underground Railroad in Chester and Neighboring Counties of Pennsylvania, they are nearly always mentioned only by their first names or have often been reduced to the role of “assistants.” Smedley overlooked the important function of free Black churches and residential communities. This article illuminates the stories of African American abolitionists in Chester County, including their part in assisting fugitives escape and the various forms of resistance in which they engaged. Utilizing original documents, letters, archival records, census data, newspapers, and the perspectives of recent historians, this article provides a frame and a context by which to understand the contributions of local Blacks to the larger story of abolition and the Underground Railroad.
Sağlıkta Yeni Bir Yönetim Anlayışı: Holakratik Yönetim
Authors: ŞEREMET Gülizar Gülcan , UÇAKKUŞ Pınar
Published: January 2023

Yönetim, ihtiyaçlar ve gelişmeler dahilinde günümüze kadar farklı şekillerde karşımıza çıkmıştır. Son zamanlarda popülerlik kazanarak yeni yeni uygulanmaya başlayan farklı bir yönetim anlayışlarından biri de holakratik yönetimdir. Holakratik yönetim anlayışının yeni bir kavram olması ile birlikte mal üreten işletmelerde uygulanabildiği alanyazın taramalarında görülmüştür. Ancak hizmet üreten işletmeler içerisinde ise holakratik yönetim uygulamasına rastlanılamamıştır. Hizmet üreten işletmelerden biri de sağlık işletmeleridir. Sağlık işletmelerinin kendine özgü matriks organizasyon yapısı ve kendine ait bir çalışma şeklinin var olması ile birlikte holakratik yönetim anlayışının uygulandığı diğer işletmelerden birtakım farklılık gösterebileceği düşünülmüştür. Bu nedenle sağlık hizmet üretimi yapan örgütler için holakratik yönetim konusu oldukça yenidir ve bu konudaki çalışmalar oldukça sınırlıdır. Bu doğrultuda hazırlanan çalışmada holakratik yönetim kavramına ve holakrasinin niteliklerine, işleyişine ilişkin alan yazın taraması yapılmış sonrasında holakratik yönetim anlayışının sağlık hizmetlerine uyarlanabilirliği ve uygulanabilirliğinin tartışılması amaçlanmıştır. Çalışma sonucunda ise holakrasi yönetim anlayışının her örgüte uyarlamasının mümkün olamayacağı aynı zamanda bu yönetim anlayışının farklı sektörlerde uygulanarak bilimsel çalışmaların yapılmasına ihtiyaç olduğu tespit edilmiştir. Çalışmanın alanyazında yapılacak olan diğer çalışmalara ışık tutacağı düşünülmektedir.
Հայ գրատպության 510-ամյակը (1512-2022 թթ.)
Authors: Սուքիասյան Գագիկ
Published: January 2023

Հայ գրքի և գրատպության պատմությունը համաշխարհային մշակույթի ու քաղաքակրթության պայծառ էջերից է, դրանց դերն ու նշանակությունը բոլոր դարերում եղել և ժամանակակից կրթության ու գիտության զարգացման համար էլ մնում են արդիական։ Արդի դարաշրջանի գլոբալ խնդիրներից է (հատկապես պատերազմական իրավիճակներում) գրքային և մշակութային ժառանգության փոխանցումը ապագա սերունդներին, որը խթանում է տեղեկատվության և սոցիալ-հաղորդակցական կապերի զարգացումը։ Հայ գրատպության 510-ամյակի (1512-2022 թթ.) հոբելյանը նոր առիթ է պատմատեսական, մշակութաբանական ու մեթոդաբանական հարցերի ուսումնասիրության տեսանկյուններից արժևորելու այն՝ որպես գրքագիտության, հայագիտության ու քաղաքակրթության զարգացման նվաճումներից մեկը։
История армянского книгопечатания одна из ярких страниц мировой культуры и цивилизации. К числу глобальных проблем современной эпохи (особенно в условиях войны) относится вопрос передачи культурного наследия будущим поколениям, что будет способствовать развитию информационных и социально-коммуникационных связей. Празднование 510-летия армянского книгопечатания (1512-2022 гг.) служит еще одним поводом для оценки и осмысления этого культурного феномена в контексте арменоведения и мировой цивилизации.
The history of Armenian book printing is one of the brightest pages of world culture and civilization, the role and significance of which deals with all periods and remain relevant for the development of modern education and science. One of the global problems of the modern era (especially in times of war), is the transfer of books and cultural heritage to future generations, contributing to the development of information and social and communication ties. The celebration of the 510th anniversary of Armenian book printing (1512-2022) is a new reason for evaluating it from the point of view of studying historical, cultural and methodological issues as one of the achievements in the development of bibliography and Armenian Studies.
Концептуализм в символике орнаментальной стилистики армянских ковров
Authors: Асцатрян Вардан
Published: January 2023

Հայաստանը գորգագործության հնագույն կենտրոններից մեկն է։ Դարեր առաջ գորգերը որպես նախասիմվոլիզմի հանրահռչակման և պահպանման միջոց էին: Գորգերը եղել են դեկորատիվ սիմվոլիզմի հանրահռչակման և պահպանման, ինչպես նաև մշակույթի այս հատվածի հետագա սերունդներին փոխանցելու ուղիներից մեկը։ Նախախորհրդանիշները համընդհանուր մարդկային զարդանախշեր են, որոնք հանդիպում են բոլոր հին ժողովուրդների մոտ: Նմանատիպ զարդանախշեր կարելի է տեսնել Ամերիկայի բնիկ ժողովուրդների, արաբների, սլավոնների, հնդիկների, չինացիների, սկանդինավների, Կենտրոնական Ասիայի, Պարսկաստանի ժողովուրդների և, իհարկե, հայերի շրջանում։ Հին հայկական գորգերի կոնկրետ ցուցանմուշներում դեկորատիվ ոճի ընդհանուր պատկերն արտահայտվում է տարբեր զարդանախշերի ներդաշնակ համադրությամբ։ Հայկական գորգերում ցուցադրված են չորս առանձին հայեցակարգային ուղղություններ՝ առասպելաբանություն, կրոնական թեմաներ, բնական երևույթներ և շրջակա միջավայր՝ տարբեր դրսևորումներով:
Армения является одним из древнейших центров ковроделия. Изначально ковры являлись средством популяризации и сохранения протосимволизма. Помимо этого посредством ковров данный сегмент культуры передавался последующим поколениям. Протосимволизм – это общечеловеческие орнаменты, которые идентичны у всех древних народов. Можно увидеть схожие орнаменты у коренных жителей Америки, арабов, славян, индийцев, китайцев, скандинавов, народов Средней Азии, Персии и, конечно же, у армян. Общая картина орнаментальной стилистики в конкретных экспонатах старинных армянских ковров выражается в целостной картине ковра, воспроизведенной в гармоничной совокупности различных орнаментов. В армянских коврах отображены четыре отдельных концептуальных направления: религиозная тематика, мифология, природные явления и окружающая среда в ее различных проявлениях.
Armenia is one of the oldest centers of carpet weaving. Initially, carpets were a method of popularizing and preserving proto-symbolism, as well as the transmission of this segment of culture to subsequent generations. Protosymbols are universal human ornaments which are found by all ancient peoples. One can trace similar ornaments among the indigenous peoples of America, by Arabs, Slavs, Indians, Chinese, Scandinavian peoples, the peoples of Central Asia, Persia, and of course by the Armenians. The general picture of the ornamental style in specific exhibits of ancient Armenian carpets is expressed in a holistic picture of the carpet, reproduced in a harmonious combination of various ornaments. The Armenian carpets are displayed in four separate conceptual directions: religious themes, mythology, natural phenomena and the environment in its various manifestations. Ornamental themes presented in Armenian carpets have a static and dynamic development.