bluuebunny/crossref_metadata_2025 huggingface dataset:
Oral capillary hemangioma mimicking gingival polyp: A Case Report
Authors: Gupta Dr. Ira , Gupta Dr. Rohit , Sarkar Dr. Saranik , Trivedi Dr. Deepika
Published: May 2022

Hemangioma is a relatively common benign proliferation of blood vessels that primarily develops during childhood. Two main forms of hemangioma recognized: capillary and cavernous. The capillary form presents as a flat area consisting of numerous small capillaries. Cavernous hemangioma appears as an elevated lesion of a deep red color, and consists of large dilated sinuses filled with blood. The present case report is an presentation of gingival growth, which was clinically diagnosed as gingival polyp but histopathologically as capillary haemangioma. These lesions present as a diagnostic dilemma to the clinician and can lead to serious complications if not carefully managed. The purpose of the case report is to present the case of a capillary hemangioma in a patient and to describe the successful treatment of this case.
Determination of Optimal Loading Conditions Using Lever Arm and Mini- Implant System for En-masse Retraction in Lingual Orthodontics – A FEM Study
Authors: Mishra Shalini , Kumar Mukesh , Goyal Manish , Kushwah Ashish
Published: May 2022

Aim: To evaluate the stress distribution along the periodontal ligament and alveolar bone by various combinations of mini-implants and lever arm used during en-masse retraction of anterior teeth using finite element method.Materialsand Methods: Four three-dimensional finite element models of the bilateral maxillary first premolar extraction casewas constructed. Lingual brackets were (0.018” slot) positioned over the center of the clinical crown. In all four models 150 g of retraction force with the help of the NiTi closed coil springs was applied with different combinations of mini-implants and lever arm. A finite element analysis was then performed to evaluate stress distribution, the principle stress, von Mises stress and displacement of the anterior teeth using ANSYS 12.1 software.Result: In this study the constructed models along with the load application were imported into ANSYS (version 12.1) software for analyzing the displacement and stress distribution corresponding to the force application. The maximum tensile stress of periodontal ligament were observed at distal root apex area of canine in all four models. Variable amount of displacements like lingual crown tipping, lingual root tipping and extrusion were observed in all the models suggesting different combinations of lever arm and mini-implants affect the direction of the tooth displacements in lingual mechanics.Conclusion: In lingual orthodontics tipping movement of crown decreases as the height of lever arm increases. It was also found that when mini-implants were placed at higher position the amount of tipping movement decreases with minimum amount of extrusion seen in central incisor and lateral incisor.
Anemia ferropriva entre adolescentes participantes do programa Bolsa Família: Análise à luz das condicionalidades de saúde
Authors: Serenini Milena , Poblacion Ana , Serenini Renan , Jorge Mota Heloisa , Gonçalves Teixeira Lilian , De Aguiar Toloni Maysa Helena , De Aguiar Carrazedo Taddei José Augusto
Published: May 2022

Objetivo: Avaliar a proporção de casos de anemia ferropriva entre adolescentes diante das condicionalidades de saúde do Programa Bolsa Família (PBF). Metodologia: Estudo transversal quantitativo com amostra de 165 adolescentes, entre 10 e 18 anos, de ambos os sexos, pertencentes às famílias participantes do PBF do município de Lavras (MG). A detecção da anemia ocorreu por meio da punção digital de uma gota de sangue utilizando hemoglobinômetro portátil Hemocue®. Foram avaliados a situação de segurança alimentar, estado nutricional e consumo alimentar. Resultados: A prevalência de anemia foi de 26%, classificada como problema de saúde pública de grau moderado. A presença de anemia associou-se ao consumo de salgado frito (p=0,020), achocolatado (p=0,042) e biscoito recheado (p=0,045). O excesso de peso esteve presente entre 21,8% dos adolescentes do sexo feminino, e entre 12,6% do sexo masculino. A prevalência de insegurança alimentar entre os adolescentes foi de 42,5%. Conclusão: Dados inéditos da alta prevalência de anemia entre adolescentes participantes do PBF na cidade de Lavras-MG são apresentados nesta pesquisa. Esses resultados evidenciam que apesar dos avanços na proposição de políticas públicas de combate à anemia, elas não estão atingindo esta faixa etária. Especificamente, o PBF é uma política pública que contribui para a prevenção e combate à anemia, porém são necessárias alterações do seu desenho metodológico, especialmente das condicionalidades de saúde, a partir do desenvolvimento de estratégias que ampliem e qualifiquem as ações de vigilância alimentar e nutricional no contexto da saúde dos adolescentes participantes do Programa Bolsa Família.
Fatores associados a lesões e dores musculoesqueléticas em praticantes de Mountain Bike
Authors: Silveira Letícia Coelho , Gualberto Pedro Ian Barbalho , Benvindo Vinícius Vieira , Pereira Beatriz Magalhães , Carvalho Pedro Henrique Berbert de , Deresz Luis Fernando
Published: May 2022

Concomitantemente à crescente popularidade do Mountain Bike (MTB), houve aumento correspondente de lesões e dores musculoesqueléticas relacionadas à modalidade. Este estudo avaliou os fatores associados à presença de lesões e dores e/ou dormência musculoesquelética (DORMs) em praticantes de MTB. O estudo foi do tipo descritivo e utilizou o questionário Nórdico Musculoesquelético para quantificar as lesões e as DORMs. Foi aplicado o teste de Qui-quadrado, ou teste exato de Fisher, para comparar proporções, e realizada regressão logística binária multivariada para verificar os previsores de lesões e DORMs. Dos 243 participantes avaliados (199 – 81,9% homens), 28 (11,52%) relataram lesões (6 – 13,64% mulheres e 22 – 11,06% homens) e 175 (72,02%) DORMs (33 – 75% mulheres e 142 – 71,36% homens). Os locais mais indicados de DORMs foram as regiões de punhos/mãos (115 – 47,33%), joelhos (44 – 18,11%) e lombar (43 – 17,70%). De acordo com a regressão logística o sobrepeso/obesidade foi preditivo para a presença de DORMs (OR=1,974, IC 95% = 1,105 – 3,526). Os dados analisados mostram que a presença de DORMs é maior do que lesões e o sobrepeso/obesidade está associado com as DORMs, indicando que este fator deve ser considerado no planejamento das atividades para evitar lesões relacionadas ao MTB.
Diversification of urban water supply: An assessment of social costs and water production costs
Authors: Ribeiro Francisco W. , da Silva Samiria M. O. , de Souza Filho Francisco de A. , Carvalho Taís M. N. , de M. Lopes Tereza M. X.
Published: May 2022

The incorporation of new water sources into a supply system requires an assessment of their economic feasibility, which, in turn, demands knowledge of their associated costs. This study calculates water production cost and evaluates social cost by applying the residual value method and calculating the shadow price for several water sources. The results indicate that desalination and industrial reuse incur similar costs, with the former being more competitive in terms of investment (US dollar (USD) 0.28/m3) and the latter in operation and maintenance (USD 0.57/m3). Cisterns and greywater reuse incur higher investment costs (USD 2.20/m3 and USD 2.60/m3, respectively), while well water has the lowest total cost (USD 0.08/m3). Desalination showed the lowest degree of distortion between shadow price and water cost and between shadow price and the average tariff; meanwhile, there was moderate distortion for industrial reuse and groundwater sources. The conclusions suggest that desalination and industrial reuse offer good flow at feasible costs and are, therefore, strategically sound sources. However, for these sources and for wells, tariff policy does not reflect a significant part of the social cost they incur.
A comparative study of various parameters of drinking water quality in Shahroud city, Iran: tap water, well water and bottled water
Authors: Ghanbarian Marjan , Roudbari Aliakbar , Nazemi Saeid , Javid Allah-Bakhsh
Published: May 2022

The physical, chemical and microbial quality of bottled water, tap water and water supplied from wells in the city of Shahroud was compared. The results of the analysis showed that the measured parameters, except in minor cases, were of national and international standards. There was no significant difference between the quality of bottled water and tap water, as well as bottled water and water available in water supply resources in the city of Shahroud. Regardless of the area in which the study was conducted, it was found that there was no need for developing other types of water treatment systems such as bottled water and domestic water treatment systems. In many cases, since bottled water is exposed to intense sunlight during the transport process, there could be a leakage of plastic monomers from the bottle wall into the water in hot or cold conditions, which can endanger consumer health. Tap water supplied from the water supply resources in the city of Shahroud was found to be completely safe and posed no threat to consumer health.
Malachite green removal using ionic flocculation
Authors: Teixeira Y. N. , Melo R. P. F. , Fernandes M. R. , Carmo S. K. S. , Neto E. L. Barros
Published: May 2022

The use of ionic flocculation is proposed to remove malachite green (MG), in this case, from water. A surfactant with the polluted solution and calcium is added. The surfactant-calcium reaction forms a precipitate, which aggregates into flocs on agitation. The flocs adsorb MG, which can then be removed by centrifugation. Ionic flocculation was assessed by varying parameters including: surfactant and MG concentrations, electrolyte content, pH, contact time, etc. The isotherm and adsorption kinetic models that best fit this process are the Langmuir and pseudo-second-order models, respectively. MG removal efficiency of 96% was obtained at pH 9, with surfactant concentration 1,400 mg L−1, MG concentration 10 mg L−1 and contact time 10 minutes. The process has potential for pollutant removal.
Leachate treatment potential of nanomaterial based assemblies: a systematic review on recent development
Authors: Vaidh Sachin , Parekh Dharni , Patel Dhara , Vishwakarma Gajendra Singh
Published: May 2022

Rapid development of the population has brought about a serious problem of waste generation and management. Open dumping and land filling are two of the preferred options for waste management and treatment. As a consequence of this, the accumulation of leachates has become one of the concerns for environmental sustainability. In this regard, various treatment methodologies have been developed in recent decades. Among them, the nanomaterial-based approaches are the emerging ones in the current scenario due to their various unique properties. Furthermore, nanomaterial-based assemblies (i.e., nanomaterials combined with microbes, chemical catalysts, enzymes, and so on) have been introduced as a novel modification for leachate treatment. This work, therefore, has been dedicated to comprehensively reviewing all nanomaterial based leachate treatment techniques. In this regard, the first part of this review will discuss the nano catalyst, nano adsorbent along with their synthesis and mechanistic view of pollutant removal potential. In the second part, the nanomaterial-based microbial conjugates applied in the leachate treatments have been discussed. Apart from this, various other nanomaterial-based methods have been discussed in the third part of the review. Hence this review is providing an insight of all the recent developments pertaining to the nano material based leachate treatment techniques.
Dimensionamento e Estudo sobre uma Bobina de Tesla
Authors: Silva Iggor Bezerra da , Nascimento Cleydson A. de C. , Oliveira Nikolas I. F. de
Published: May 2022

Esse artigo apresenta um projeto e análise dos parâmetros de construção de uma Bobina de Tesla (BT). A BToferece uma apresentação de vários fenômenos físicos da eletrostática e eletrodinâmica, como o efeito corona e indutância induzida, isso faz dela uminstrumentodidático aplicávelpara acompanhamento de estudos práticos em instituições de ensino. O objetivo deste trabalhoédescrevere relacionaras etapas de construção de um projeto de uma BTe fazer uma verificação da confiabilidade do método de cálculo convencional para determinação dosparâmetros da BT. É feita a comparaçãodos resultados obtido de maneira convencionalcom o gerado por um software computacional, WinTesla. Vale ressaltar que os fatores que são responsáveis pela diferença, entre os resultados dos dois métodos, são as limitações de arredondamentos dos parâmetros que o programa apresenta.
Trends in the Pharmaceutical Design of New Psychoactive Substances Detected in
Oral Fluid OF Drivers Around a Music Festival in South-West France: Comparison
2019/2017
Authors: Gish Alexandr , Dumestre-Toulet Véronique , Richeval Camille , Wiart Jean-François , Hakim Florian , Allorge Delphine , Gaulier Jean-michel
Published: May 2022

Objective:

new psychoactive substance use (NPS) is a reality in France, including among drivers. This work aims (i) to report pharmaceutical design of NPS detected in oral fluid (OF) from drivers initially screened for drugs around a music festival in 2019, and (ii) to compare obtained results with those of a previous similar study carried out in 2017 in the same situation (and the same music festival) and according to the same methodology.

Methods:

OF specimens were recovered from the used devices of the salivary immunochemical tests used by the police during the controls carried out at the entering and leaving the festival. These OF were analyzed using a liquid chromatography coupled with tandem mass spectrometry and high-resolution mass spectrometry methods using mass spectra libraries of approximately 1700 substances including (in 2020) more than 650 NPS and metabolites.

Results:

NPS were detected in 14 out of the 265 collected OF specimens. Ten NPS were identified (number of identification): APINACA (1), AB-Chminaca (1), 5F-AMB (1), 5F-PB-22 (5), 2C-D (1), methoxetamine (2), ketamine (1), x-CMC (1), 4-MEC (2), ethylone (2). The prevalence of NPS detection in OF (5.2%) is in the same order than the observed one in 2017 (6.8%) but these results are marked by the majority and increasing proportion of synthetic cannabinoids (47% of identified NPS in 2019 vs 25% in 2017), an increase also in the proportion of cathinone derivatives (29% in 2019 vs 6 % in 2017), and a decrease in cyclohexanones (17% in 2019 vs 43% in 2017).

Conclusion:

these pharmaceutical design trends (2019 vs 2017) observed in a population of drivers around a music festival seem to reflect those that can be seen in more general populations in France, with probably a rise in the consumption of synthetic cannabinoids.
Docosahexaenoic Acid Ester of Phloridzin Reduces Inflammation and Insulin Resistance
via AMPK
Authors: Chen Jingqing , Wu Zhenlong , Wang Jin , Si Xuemeng , Zhang Rui , Sun Tianqi , Dong Qiaoyan , Wu Wenqing , Qiu Yefeng
Published: May 2022

Background:

Docosahexaenoic acid-acylated phloridzin (PZ-DHA), a novel polyphenol fatty acid
ester derivative, is synthesized through an acylation reaction of phloridzin (PZ) and docosahexaenoic acid
(DHA). PZ-DHA is more stable than DHA and exhibits higher cellular uptake and bioavailability than PZ.

Objective:

The study aims to investigate the effects of PZ-DHA on insulin resistance in the skeletal muscle and
the related mechanisms; we used palmitic acid (PA)-treated C2C12 myotubes as an insulin resistance model.

Results:

We found that PZ-DHA increased the activity of AMP-activated protein kinase (AMPK) and improved
glucose uptake and mitochondrial function in an AMPK-dependent manner in untreated C2C12 myotubes.
PZ-DHA treatment of the myotubes reversed PA-induced insulin resistance; this was indicated by increases in
glucose uptake and the expression of membrane glucose transporter 4 (Glut4) and phosphorylated Akt. Moreover,
PZ-DHA treatment reversed PA-induced inflammation and oxidative stress. These effects of PZ-DHA were
mediated by AMPK. Furthermore, the increase in AMPK activity, improvement in insulin resistance, and
decrease in inflammatory and oxidative responses after PZ-DHA treatment diminished upon co-treatment with
a liver kinase B1 (LKB1) inhibitor, suggesting that PZ-DHA improved AMPK activity by regulating its
upstream kinase, LKB1.

Conclusion:

The effects of PZ-DHA on insulin resistance in C2C12 myotubes may be mediated by the LKB1-
AMPK signaling pathway. Hence, PZ-DHA is a promising therapeutic agent for insulin resistance in type 2
diabetes.
Identification of Hypoxia-related Genes in Acute Myocardial Infarction
using Bioinformatics Analysis
Authors: Wu Yanqing , Xia Huasong , Chen Yi , Chen Qiang
Published: May 2022

Background:

Acute myocardial infarction (AMI) remains one of the most fatal diseases worldwide. Persistent ischemia and hypoxia are implicated as a significant mechanism in the development of AMI. However, no hypoxia-related gene targets of AMI have been identified to date. This study aimed to identify potential genes and drugs for AMI using bioinformatics analysis.

Material and methods:

Two datasets both related to AMI (GSE76387 and GSE161427) were downloaded from the Gene Expression Omnibus to identify differentially expressed genes (DEGs) between AMI and sham mice. Gene ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed. A protein-protein interaction (PPI) network was constructed to identify hub genes using Cytoscape. Candidate genes were identified by the intersection of hub genes and hypoxia-related genes. Western blotting was used to validate the candidate genes in the AMI mouse model. Furthermore, the Drug-Gene Interaction Database was used to predict potential therapeutic drugs targeting all hub genes.

Results:

Fifty-three upregulated and 16 downregulated genes closely related to AMI were identified. The DEGs were primarily enriched in protein, heparin and integrin binding. KEGG analysis suggested that focal adhesion, PI3K-Akt signaling pathway, and extracellular matrix-receptor interaction are crucial pathways for AMI. The PPI network analysis identified 14 hub genes, two of which were hypoxia-related. Several agents were found to have therapeutic potential for AMI.

Conclusion:

This study suggests that connective tissue growth factor and the collagen family members may be candidate targets in treating AMI. Agents targeting these candidates may be potential treatments.
WITHDRAWN: Essential Oil Compositions, Antioxidant Activities, and Procollagen Synthesis Abilities of Four Lavandula angustifolia Varieties
Authors: Deng Xiaoli , Lu Zhaoyi , Chen Jiahan , Chen Wen
Published: May 2022

Since the authors are not responding to the editor’s requests to fulfill the editorial requirement, therefore, the article has been
withdrawn from the journal Current Pharmaceutical Biotechnology.

Bentham Science apologizes to the readers of the journal for any inconvenience this may have caused.

The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policies-main.php.

BENTHAM SCIENCE DISCLAIMER:

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authors, if plagiarism or fabricated information is discovered. By submitting a manuscript the authors agree that the copyright
of their article is transferred to the publishers if and when the article is accepted for publication.
On the Potential Significance of the Intrinsically Disordered Regions in the
Clostridiodes difficile Toxins A and B
Authors: El Hadidy Nashwa , Uversky Vladimir N. , Sun Xingmin
Published: May 2022

Background:

Clostridiodes (or Clostridium) difficile is a spore-forming, Gram-positive
anaerobic bacterium that may cause symptoms ranging from diarrhea to pseudomembranous colitis.
During the C. difficile infection (CDI), the two primary bacterial toxins, toxin A (TcdA) or toxin B
(TcdB), disrupt host cell function mainly through the inactivation of small GTPases that regulate the
actin cytoskeleton. Both toxins have complex structural organization containing several functional
domains.

Methods:

Analytical bioinformatics tools are used to compare the extent of disorder within TcdA and
TcdB proteins, and to see if the existence of structural disorder can be used to explain the difference
in the functionality of these toxins.

Results:

This paper’s aim is to offer an overall review of the structural and functional differences between
TcdA and TcdB.

Conclusions:

Results of our multifactorial bioinformatics analysis revealed that intrinsic disorder may
play a role in the multifunctionality of C. difficile major toxins TcdA and TcdB, suggesting that intrinsic
disorder may be related to their pathogenic mechanisms.
Modulation of ATP8B1 Gene Expression in Colorectal Cancer Cells
Suggest its Role as a Tumor Suppressor
Authors: Althenayyan Saleh , AlGhamdi Amal , AlMuhanna Mohammed H. , Hawsa Esra , Aldeghaither Dalal , Iqbal Jahangir , Mohammad Sameer , Aziz Mohammad A.
Published: May 2022

Aim: The study aims to understand the role of tumor suppressor genes in colorectal cancer
initiation and progression.

Background: Sporadic colorectal cancer (CRC) develops through distinct molecular events. Loss
of the 18q chromosome is a conspicuous event in the progression of adenoma to carcinoma. There
is limited information regarding the molecular effectors of this event. Earlier, we had reported ATP8B1
as a novel gene associated with CRC. ATP8B1 belongs to the family of P-type ATPases (P4
ATPase) that primarily function to facilitate the translocation of phospholipids.

Objective: In this study, we attempt to implicate the ATP8B1 gene located on chromosome 18q as
a tumor suppressor gene.

Methods: Cells culture, Patient data analysis, Generation of stable ATP8B1 overexpressing
SW480 cell line, Preparation of viral particles, Cell Transduction, Generation of stable ATP8B1
knockdown HT29 cell line with CRISPR/Cas9, Generation of stable ATP8B1 knockdown HT29
cell line with shRNA, Quantification of ATP8B1 gene expression, Real-time cell proliferation and
migration assays, Cell proliferation assay, Cell migration assay, Protein isolation and western blotting,
Endpoint cell viability assay, Uptake and efflux of sphingolipid, Statistical and computational
analyses.

Results: We studied indigenous patient data and confirmed the reduced expression of ATP8B1 in
tumor samples. CRC cell lines were engineered with reduced and enhanced levels of ATP8B1,
which provided a tool to study its role in cancer progression. Forced reduction of ATP8B1 expression
either by CRISPR/Cas9 or shRNA was associated with increased growth and proliferation of
CRC cell line - HT29. In contrast, overexpression of ATP8B1 resulted in reduced growth and proliferation
of SW480 cell lines. We generated a network of genes that are downstream of ATP8B1.
Further, we provide the predicted effect of modulation of ATP8B1 levels on this network and the
possible effect on fatty acid metabolism-related genes.

Conclusion: Tumor suppressor gene (ATP8B1) located on chromosome 18q could be responsible
in the progression of colorectal cancer. Knocking down of this gene causes an increased rate of cell
proliferation and reduced cell death, suggesting its role as a tumor suppressor. Increasing the expression
of this gene in colorectal cancer cells slowed down their growth and increased cell death.
These evidences suggest the role of ATP8B1 as a tumor suppressor gene.
Mechanistic Insight and Possible Mechanism of Seizure in Covid-19: The
Nuances and Focal Points
Authors: Al-Kuraishy Hayder M. , Al-Gareeb Ali I. , Rauf Abdur , Alhumaydhi Fahad A. , Kujawska Małgorzata , El-Saber Batiha Gaber
Published: May 2022

Coronavirus disease 2019 (COVID-19) is a primary respiratory disease with an alarming
impact worldwide. COVID-19 is caused by severe acute respiratory syndrome coronavirus type 2
(SARS-CoV-2) and presents various neurological symptoms, including seizures. SARS-CoV-2 shows
neuroinvasive and neurotropic capabilities through a neuronal angiotensin-converting enzyme 2
(ACE2), which is also highly expressed in both neuronal and glial cells. Therefore, SARS-CoV-2 can
trigger neuroinflammation and neuronal hyperexcitability, increasing the risk of seizures. Olfactory
neurons could be an exceptional neuronal pathway for the neuroinvasion of respiratory viruses to access
the central nervous system (CNS) from the nasal cavity, leading to neuronal injury and neuroinflammation.
Although neuronal ACE2 has been widely studied, other receptors for SARS-CoV-2 in
the brain have been proposed to mediate viral-neuronal interactions with subsequent neurological
squeals. Thus, the objective of the present critical review was to find the association and mechanistic
insight between COVID-19 and the risk of seizures.
Legal Regulation of Protection of Natural Objects
Authors: Anisimov Aleksey , Ryzhenkov Anatoliy
Published: May 2022

All types of natural objects are closely interlinked with each other.
Deterioration of the quality of one of them inevitably leads to particular consequences
for the condition of the other elements of the ecological system. This is why legislation
stipulates a range of measures aimed at protecting both the environment in general and
its constituent components. Land protection focuses on the preservation of soil fertility.
From the analysis of the Forest Code of the Russian Federation it follows that there are
nature protection rules of a general nature covering all types of forests and special rules
specifying these general provisions for certain categories of forests. In particular, the
general environmental rules consist in the fact that all forests are subject to protection
from fires, pollution (including contamination by radioactive substances) and other
negative impact as well as protection from harmful organisms. The legal regime of
water bodies varies depending on whether they are located on the surface of the earth
or they are ground water bodies. The Government of the Russian Federation approved
special rules for protection of both surface and ground water bodies. The task of water
protection is solved by imposing duties on the subjects of water relations – citizens and
legal entities as well as public authorities. For the purpose of water protection,
environmental and water laws establish a range of general and special requirements.
The protection of fauna habitat is one of the areas of fauna protection activities.
Legislation establishes two regimes of the protection of animals. The general regime of
the protection is established by the Federal Law “On Fauna” (based on the criterion of
the possibility of being an object of hunting and fishing, two categories of animals are
distinguished); the special regime is established in relation to animals attributed to
specially protected ones, including those listed in the Red Data Book of Russia.
Researchers point out two main problems in the area of rational use and protection of
subsoil. They are the inefficient use of subsoil resources with the increasing complexity
of field exploitation and the growing impact of mining on the environment. Finally, the
consistent system of legal rules regulating the protection of air from anthropogenic
impact is considered at the end of this Chapter.
Klinische Bewegingswetenschappen: theoretisch geïnspireerd toegepast wetenschappelijk onderzoek
Authors: Houdijk Han
Published: May 2022

Han Houdijk is hoogleraar Klinische Bewegingswetenschappen. Tijdens zijn inaugurele rede gaat Houdijk in op hoe de bewegingswetenschappen theorieën en modellen - uit onder andere de biomechanica, inspanningsfysiologie en motorisch leren - gebruiken om het normale en gestoorde bewegen te begrijpen en hoe daar innovatieve klinische behandelstrategieën uit kunnen worden afgeleid. Klinische bewegingswetenschappen beweegt zich op het raakvlak van wetenschap en praktijk. Vaak wordt gezegd dat daarbij de kloof tussen wetenschap en praktijk moet worden gedicht. Een vruchtbare samenwerking bestaat echter bij de gratie van deze kloof. Deze stelling wordt gevoed door de fundamentele verschillen tussen beide domeinen. De clinicus richt zich op de individuele patiënt in zijn gehele bio-psychosociale werkelijkheid. De wetenschapper richt zich op algemene wetmatigheden en kijkt naar een enkel aspect van gedrag van de patiënt dat gecontroleerd kan worden gemanipuleerd en gemeten. Een vruchtbare samenwerking vraagt allereerst om het onderkennen van deze verschillen, om vervolgens kennis en expertise uit te wisselen met als doel de zorg te verbeteren. Innovaties klinische behandelstrategieën Samen met de klinische praktijk hebben we innovaties in de afgelopen jaren ingepast binnen de complexe werkelijkheid van mensen met bijvoorbeeld een beroerte, beenamputatie, of dwarslaesie. Deze theoretische geïnspireerde aanpak maakt het mogelijk om behandelprincipes uit te wisselen tussen deze patiëntgroepen die in klinische zin erg van elkaar verschillen. Maar ook om principes, die ertoe bijdragen dat schaatsers sneller schaatsen op de klapschaats, in te zetten in de ontwikkeling van prothesen en spalken waarmee patiënten weer sneller kunnen lopen.
Raising the Bar: The Role of the Reporting Procedure of the United Nations Human Rights Committee in the Protection of Human Rights in Africa
Authors: Ibrahim Aliyu
Published: May 2022

The United Nations Human Rights Committee (HRC) is saddled with the responsibility of supervising the implementation of the provisions of the ICCPR by its state parties. However, it is only the reporting procedure that mandates each state party to submit a report to the HRC periodically, outlining the steps it has taken to fulfil its obligations to the treaty. Over the years, it was observed that states tend to embellish these reports before submitting them to the HRC because it had no means of checking the veracity of the contents of the reports. Consequently, the HRC has continued to introduce novel ways of checking the accuracy of the state parties’ reports, which includes the Committee partnering with National Human Rights Institutions (NHRIs) and Non-Governmental Organisations (NGOs) within the territories of state parties. This is to monitor the implementation of the provisions of the ICCPR and submit alternative reports to the HRC for it to have a more objective perspective on the level of the state compliance. To examine the effectiveness of the reporting procedure among African state parties, two states (Morocco and Rwanda) have been selected with the aim of gauging the effect of the reporting procedure in influencing state parties to fulfil their obligations to the treaty. In the course of the study, the jurisprudence of the HRC and domestic legislation of states were analysed and it is observed that for the HRC to be more effective it needs more visibility, especially within the African Continent.
Morbidity Patterns in Primary Care in Hong Kong: Protocol for a Practice-Based Morbidity Survey (Preprint)
Authors: Chen Julie Yun , Chao David , Wong Samuel Yeung-shan , Tse Tsui Yee Emily , Wan Eric Yuk Fai , Tsang Joyce Pui Yan , Leung Maria Kwan Wa , Ko Welchie , Li Yim-chu , Chen Catherine , Luk Wan , Dao Man-Chi , Wong Michelle , Leung Wing Mun , Lam Cindy Lo Kuen
Published: May 2022

BACKGROUND

Up-to-date and accurate information about the health problems encountered by primary care doctors is essential to understanding the morbidity pattern of the community to better inform health care policy and practice. Morbidity surveys of doctors allow documentation of actual consultations, reflecting the patient’s reason for seeking care as well as the doctor’s diagnostic interpretation of the illness and management approach. Such surveys are particularly critical in the absence of a centralized primary care electronic medical record database.

OBJECTIVE

With the changing sociodemographic profile of the population and implementation of health care initiatives in the past 10 years, the aim of this study is to determine the morbidity and management patterns in Hong Kong primary care during a pandemic and compare the results with the last survey conducted in 2007-2008.

METHODS

This will be a prospective, practice-based survey of Hong Kong primary care doctors. Participants will be recruited by convenience and targeted sampling from both public and private sectors. Participating doctors will record the health problems and corresponding management activities for consecutive patient encounters during one designated week in each season of the year. Coding of health problems will follow the International Classification of Primary Care, Second Edition. Descriptive statistics will be used to calculate the prevalence of health problems and diseases as well as the rates of management activities (referral, investigation, prescription, preventive care). Nonlinear mixed effects models will assess the differences between the private and public sectors as well as factors associated with morbidity and management patterns in primary care.

RESULTS

The data collection will last from March 1, 2021, to August 31, 2022. As of April 2022, 176 doctor-weeks of data have been collected.

CONCLUSIONS

The results will provide information about the health of the community and inform the planning and allocation of health care resources.

CLINICALTRIAL

ClinicalTrials.gov NCT04736992; https://clinicaltrials.gov/ct2/show/NCT04736992

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/37334
Deconstructing TikTok Videos on Mental Health: Cross-sectional, Descriptive Content Analysis (Preprint)
Authors: Basch Corey H , Donelle Lorie , Fera Joseph , Jaime Christie
Published: May 2022

BACKGROUND

Social media platforms that are based on the creation of visual media, such as TikTok, are increasingly popular with adolescents. Online social media networks provide valuable opportunities to connect with each other to share experiences and strategies for health and wellness.

OBJECTIVE

The aim of this study was to describe the content of the hashtag #mentalhealth on TikTok.

METHODS

This cross-sectional, descriptive content analysis study included 100 videos with the hashtag #mentalhealth on TikTok. All videos that included the hashtag #mentalhealth were analyzed and coded for the presence of content categories. Additionally, the comments to each video were viewed and coded for content in the following themes: offering support or validation; mentioning experience with suicide or suicidal ideation; mentioning experience with self-harm; describing an experience with hospitalization for mental health issues; describing other mental health issues; and sharing coping strategies, experiences of healing, or ways to feel better.

RESULTS

Collectively, the 100 videos studied received 1,354,100,000 views; 266,900,000 likes; and 2,515,954 comments. On average, each video received 13,406,930.69 (SD 8,728,095.52) views; 2,657,425.74 (SD 1,449,920.45) likes; and 24,910.44 (SD 21,035.06) comments. The only content category observed in most (51/100, 51%) of the videos included in the sample was “general mental health.” The remaining content categories appeared in less than 50% of the sample. In total, 32% (32/100) of the videos sampled received more than the overall average number of likes (ie, more that 2.67 million likes). Among these 32 videos, 23 (72%) included comments offering support or validation and 20 (62%) included comments that described other mental health issues or struggles.

CONCLUSIONS

With over 1 billion cumulative views, almost half of the assessed TikTok videos included in this study reported or expressed symptoms of mental distress. Future research should focus on the potential role of intervention by health care professionals on social media.
Періопераційний менеджмент відповідно до принципів програми швидкого післяопераційного відновлення (ERAS) у профілактиці гострої кишкової непрохідності (клінічна лекція)
Authors: Pylypenko M.M. , Bondar M.V. , Khomenko O.Yu.
Published: May 2022

У статті наведені основні напрямки профілактики розвитку гострої кишкової непрохідності в пацієнтів після оперативних втручань. Основу профілактики становлять принципи швидкого післяопераційного відновлення за програмою ERAS, що широко застосовується в різних галузях. Базові принципи програми ERAS відповідають трьом періодам: передопераційному, інтраопераційному й післяопераційному. У передопераційному періоді велику увагу приділяють підготовці пацієнта й корегуванню станів, що можуть бути причиною тривалого відновлення після операції (наприклад, анемії). Інтраопераційно рекомендують застосовувати комбіновані принципи анестезії, що дозволяють зменшити використання опіатів та анестетиків, на основі регіонарних і місцевих методів знеболювання. На цьому етапі важливим є якісний моніторинг, що дозволяє запобігти інтраопераційній гіпо- і гіперволемії. Під час післяопераційного періоду ключову роль відіграють якісне знеболювання, профілактика нудоти й блювання, ранній початок ентерального харчування пацієнтів і рання рухова активність пацієнтів.
Phytoplankton Composition of Different Fresh Waterbodies of Bhopal
Authors: Dixit Mahima
Published: May 2022

Abstract: In the present study the area of investigation confined to the four lakes of Bhopal, which are Upper lake, Lower lake, Shahpura lake and Motia lake. Samples were collected monthly from December 2008 to November 2010 from two sampling stations at different depth: epilimnion and hypolimnion layer. During the study period different composition of algal group were observed. In the study period 115 genera of algae belonging to five major groups viz., 60 genera of Chlorophyceae, 22 genera of Cyanophyceae and 27 genera of Bacillariophyceae, 4 genera of Euglenophyceae and 2 genera of Xanthophyceae were identified in upper lake, 63 genera belonging to three major groups viz, 29 genera of Chlorophyceae, 20 genera of Cyanophyceae and 14 genera of Bacillariophyceae were identified in lower lake, 53 genera belonging to three major groups Viz., 28 species of Chlorophyceae, 13 genera of Cyanophyceae, 12 genera of Bacillariophyceae were identified in shahpura lake and 43 genera belonging to three major groups viz., 21 genera of Chloraphyceae, 12 genera of Cyanophyceae and 10 genera of Bacillariophyceae were identified in motia lake. Keywords: Epilimnion, Hypolimnion, Chlorophyceae, Bacillariophyceae, Cyanophyceae, Euglenophyceae, Xanthophyceae.
Avances en biotecnología agrícola en Risaralda
Authors: Colonia Orozco Ana María
Published: May 2022

La presente publicación busca ofrecer a un público amplio, fundamentos en biotecnología y resultados obtenidos de la investigación científica en el área Agrícola y la formación posgradual, en el marco del proyecto Desarrollo de capacidades científicas y tecnológicas en biotecnología aplicadas a los sectores de la salud y la agroindustria en el departamento de Risaralda. Este programa fue financiado con recursos del Sistema General de regalías, vigencia 2014– 2019, con contrapartida y ejecución de la Universidad tecnológica de Pereira y la participación de la Universidad Libre (seccional Pereira). Este programa de investigación científica buscó proponer alternativas, transferir conocimientos, cualificar la formación de los investigadores e integrar la Universidad al medio externo. Este libro presenta elementos generales y resultados específicos, asociados al manejo y aprovechamiento de cultivos y plantas. Se encuentra estructurado en tres secciones: Contextos, ciencia y tecnología; Ejemplos de aplicaciones de biotecnología; e Investigaciones de formación posgradual. A su vez se organizan en nueve capítulos, de manera que le facilite al lector comprender los principios y las aplicaciones de la biotecnología en el área de la producción, la bioprospección y la búsqueda de alternativas de manejo y producción. En esencia, se busca aprovechar la biodiversidad, con criterios éticos, ambientales y de beneficio social para productores y consumidores.
La dirección escolar en la normativa vigente de la provincia de Córdoba
Authors: Yelicich Carolina
Published: May 2022

Centramos nuestra atención, en este artículo, en las normativas que se han producidoen las últimas décadas para regular la función directiva y organizar la tarea delos directivos escolares de nivel secundario de la provincia de Córdoba (Argentina).Las normativas desactualizadas, la multiplicidad de deberes, tareas y atribuciones yel escaso énfasis en la consolidación de equipos directivos constituyen algunas de lasproblemáticas que se derivan de la reglamentación vigente.El presente trabajo forma parte de una investigación doctoral en proceso, centrada enel trabajo de los directivos de dos centros escolares de nivel secundario en la ciudad deCórdoba, Argentina, y en la ciudad de Málaga, España. En la investigación, se efectúaun estudio cualitativo con enfoque etnográfico, el cual utiliza -como fuentes de información-el análisis de documentos, las entrevistas en profundidad y la observacióndirecta. En esta presentación, se focaliza en la situación del caso cordobés.
La nueva normalidad de los jóvenes universitarios españoles: vocación en tiempos de pandemia
Authors: Escamilla Alonso , Martín Teresa
Published: May 2022

El objetivo de la presente investigación fue identificar si la modalidadde enseñanza universitaria (presencial vs. semipresencial/virtual) tiene influencia enlas percepciones de los universitarios españoles en relación al aislamiento social, alhorario académico irregular, a las preocupaciones económicas y al abandono de losestudios. Se analizó la asociación de las variables a través de tablas de contingencia ypruebas de ji al cuadrado de Pearson. Aunque las hipótesis no llegan a confirmarse, loshallazgos parecen indicar que, con una muestra estadísticamente significativa, los universitariosen modalidad semipresencial/virtual se sentirán más aislados socialmente,tendrán un horario académico irregular, mayores preocupaciones económicas y serámás frecuente el abandono de los estudios en este nivel.
Sobre el objeto de intervención en psicopedagogía
Authors: Bertoldi Sandra , Enrico Liliana , Sánchez María Daniela , Fernández María Luján
Published: May 2022

En el campo psicopedagógico existen teorías procedentes de diversas disciplinas que implican una relación entre conceptos teóricos y prácticas profesionales y nos advierten sobre acuerdos epistemológicos e ideológicos implícitos acordes con el contexto histórico, cultural y sociopolítico.En este artículo, compartimos los resultados preliminares de un trabajo de investigación en curso que se pregunta sobre las opciones epistemológicas que orientan las elecciones teóricas de psicopedagogas referentes argentinas a la hora de definir el objeto disciplinar y el objeto de intervención en sus prácticas.Para ello, se presentan algunas aproximaciones teórico-epistemológicas sobre la noción de objeto de intervención y, a partir de algunos indicadores identificados en las producciones escritas de las referentes, se sistematiza y teoriza desde la perspectiva epistemológica crítico-reflexiva sobre el recorte de objeto considerado psicopedagógico y los criterios de su delimitación.El estudio permite apreciar una similitud importante respecto al recorte del objeto de intervención, aunque no sin diferencias en el posicionamiento teórico.
Análisis de la jugabilidad en un ambiente virtual colaborativo: estudiantes de preescolar como personas usuarias expertas
Authors: Paniagua-Esquivel Cristina , Rodríguez Rosemary Alfaro , Fornaguera-Trías Jaime
Published: May 2022

El ingreso de la tecnología en los centros educativos (para este caso, computadoras) viene acompañado de programas informáticos que buscan apoyar el proceso de enseñanza y aprendizaje. En preescolar, se proponen videojuegos que promueven habilidades de socialización. Estos requieren ser evaluados y, para esto, se presenta la jugabilidad como sistema de diseño y análisis. Se utiliza a las personas hacia quienes se dirige el videojuego como personas con criterios expertos. El presente estudio tuvo dos objetivos: desarrollar y validar un instrumento para evaluar un ambiente virtual colaborativo (AVC) al utilizar los parámetros de jugabilidad y estudiantes de preescolar como criterios expertos. Se hizo una fase piloto en donde se entrevistó a participantes y, con estas respuestas, se implementaron mejoras al juego y se inició una fase de evaluación con 110 participantes. El resultado fue un protocolo que calificó el AVC y un videojuego que es apto para estudiantes de preescolar.
Comprensión lectora, producción de textos y bienestar socioemocional en estudiantes de 2.º de básica primaria de la región de Arica y Parinacota, Chile
Authors: Huarache Ocaña Francisco Alexis
Published: May 2022

El objetivo del estudio fue conocer el desempeño de un grupo de alumnos de básica primaria de la región de Arica y Parinacota en Chile, en las variables producción de textos (PT), bienestar socioemocional (BS), y comprensión lectora (CL). La muestra estuvo constituida por 231 estudiantes de veinticuatro instituciones educacionales. Se emplearon la prueba de comprensión lectora y producción de textos y el autorreporte de bienestar socioemocional para niños. Los resultados indicaron que el grupo de hombres tuvo un mejor desempeño en la variable CL; las mujeres, mejores resultados en la variable PT y, en la comparación por ubicación geográfica, el grupo rural mostró un mejor desempeño en la variable BS.
Effects of Gopher Tortoise (Gopherus polyphemus) Exclusion on Plant Assemblages in a Longleaf Pine Forest
Authors: Lloyd Robin , Henning Jeremiah , Chupp Adam
Published: May 2022

Herbivory serves as a critical top-down mechanism within plant
communities by regulating biodiversity, productivity, and ecosystem
function. While top-down impacts of mammalian herbivores have garnered
significant attention in the literature, fewer studies have investigated
the role of herbivorous reptiles in regulating plant communities, which
can serve as crucial herbivores in some ecosystems. In Southeastern
United States coastal plain long-leaf pine forests, the gopher tortoise
(Gopherus polyphemus) is a keystone species that may suppress
plant productivity and promote local diversity within hyper-diverse
understory plant communities. In January 2019, we established
tortoise-exclusion plots within an active gopher tortoise population at
Splinter Hill Bog Preserve in southwest Alabama, USA. We measured the
response of plant species diversity, composition. and productivity
through a single growing season to quantify the short-term impacts of
tortoise-excluded plots on understory plant communities. We found that
plots excluded tortoises had 35% more plant cover with a 15% reduction
in plant richness, 6% reduction in evenness, and 12% reduction in
Shannon’s diversity relative to control plots. Within a single growing
season, we found that tortoise exclusion explained 5% of the variation
within overall plant community composition. Our results provide clear
evidence on the role of gopher tortoise herbivory for the maintenance of
plant diversity within the species-rich longleaf pine forests of the
Southeastern United States, even at short time scales and in an
heterogeneous environment.