bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMULASI DAN DAYA TERIMA SNACK BAR BERBASIS TEPUNG IKAN LELE DAN KEDELAI SEBAGAI ALTERNATIF SNACK IBU HAMIL DALAM MENCEGAH STUNTING
Authors: Nathasa Weisdania Sihite  , Mutiara Balqis  , Mardiana
Published: February 2025

Upaya pencegahan stunting pada bayi dan balita dapat dilakukan sejak awal kehamilan. Prinsipnya adalah dengan  meningkatkan asupan gizi bagi ibu hamil dengan memastikan ibu hamil dapat mengkonsumsi makanan yang berkualitas  selama masa kehamilan. Tujuan penelitian ini adalah diketahui hasil dari formulasi dan daya terima snack bar (tepung ikan lele dan tepung kedelai) sebagai alternatif snack ibu hamil dalam pencegahan stunting. Penelitian ini menggunakan  penelitian eksperimen dengan rancangan percobaan yang digunakaan yaitu Rancangan Acak Lengkap (RAL) non faktorial,  analisis proksimat dilakukan di PT Saraswanti Indo Genetech Bogor. Hasil penelitian menunjukkan bahwa kandungan proksimat pada snack bar  yaitu kadar air 8,57%, kadar abu 2,55%, energi 477,12 kkal, protein 21,86 gr, lemak 24,32 gr,  karbohidrat 42,71 gr, zat besi 4,47 mg, kalsium 65,61 mg. Hasil analisa ini menyatakan bahwa snack bar ini secara daya  terima, disukai oleh panelis dan berdasarkan hasil dari kandungan proksimat yang ada, dapat dikatakan bahwa snack  bar ini dapat dijadikan solusi untuk memenuhi kebutuhan zat gizi ibu hamil yang membutuhkan energi dan protein yang tinggi.
PENGARUH PENAMBAHAN COATING KITOSAN TERHADAP KUALITAS IKAN SALEM PINDANG (Scomber japonicus) YANG DIKEMAS VAKUM SELAMA PENYIMPANAN SUHU RUANG
Authors: Muhammad Hauzan Arifin  , Lukita Purnamayati
Published: February 2025

Salah satu produk olahan perikanan adalah pindang ikan, yang biasanya dijual tanpa kemasan. Pengemasan vakum  adalah salah satu metode pengemasan yang efektif untuk menjaga kualitas dan keamanan produk perikanan. Pindang ikan  yang dikemas dengan metode ini biasanya tidak bertahan lebih dari 7 hari, jadi diperlukan bahan pengawet seperti kitosan. Tujuan dari penelitian ini adalah untuk menentukan konsentrasi kitosan yang optimal terhadap nilai kadar air, susut bobot,  pH, total plate count (TPC), kualitas organoleptik, dan pH dalam pindang ikan yang disimpan dalam kemasan vakum yang  disimpan pada suhu ruang. Rancangan Acak Lengkap (RAL) Faktorial digunakan dalam penelitian ini, bersama dengan faktor konsentrasi kitosan dan waktu penyimpanan. Uji statistik ANOVA dan BNJ digunakan untuk menganalisis data  parametrik. Kruskal-Wallis dan Mann-Whitney digunakan untuk menganalisis data non-parametrik. Hasil penelitian menunjukkan bahwa semua parameter uji pada ikan salem pindang secara nyata dipengaruhi oleh kitosan dan durasi  penyimpanan. Dengan penambahan 1% kitosan, ikan salem pindang mencapai hasil terbaik selama 12 hari dengan kadar  air 46,25%; susut bobot 20%; pH 6,38; TPC 7,6 log CFU/g; dan selang interval organoleptik umum 5,66–7,44. Selama 12  hari penyimpanan. Coating kitosan dapat mempertahankan kualitas dan ikan salem pindang yang dikemas vakum, tetapi tidak dapat menekan nilai TPC lebih dari hari pertama penyimpanan di suhu ruang
KARAKTERISTIK FISIKOKIMIA DAN ORGANOLEPTIK SOSIS TEMPE SIAP MAKAN DENGAN PENAMBAHAN Spirulina platensis DAN GLUKOMANAN
Authors: Siti Nurfadillah Hasibuan  , Rosida  , Rahmawati
Published: February 2025

Sosis tempe siap makan merupakan produk diversifikasi pangan berbasis protein nabati dan salah satu inovasi produk berbahan dasar tempe. Dalam rangka meningkatkan karakteristik produk dan variasi inovasi produk yang bergizi dan berkualitas, penelitian ini mengembangkan penambahan Spirulina platensis dan glukomanan dalam sosis tempe siap makan. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan Spirulina platensis dan glukomanan terhadap karakteristik fisikokimia dan organoleptik serta kombinasi perlakuan terbaik sosis tempe siap makan. Desain pada penelitian menggunakan Rancangan Acak Lengkap (RAL) dua faktor. Faktor I adalah konsentrasi Spirulina platensis (100 ppm, 250 ppm, 500 ppm). Faktor II adalah konsentrasi glukomanan (5%, 10%, 15%). Analisis data hasil penelitian menggunakan ANOVA dengan tingkat kepercayaan 5% dan dilanjutkan dengan uji lanjut DMRT serta pemilihan perlakuan terbaik menggunakan metode De Garmo. Hasil penelitian menunjukkan bahwa formulasi terbaik sosis tempe siap makan diperoleh pada penambahan Spirulina platensis 500 ppm dan glukomanan 10% (S3G2) yang menghasilkan kekenyalan 30,41 N, susut masak 6,62%, WHC 46,59%, kadar air 56,83%, kadar abu 4,05%, kadar protein 15,89%, kadar lemak 4,46%, kadar karbohidrat 18,76%, serta nilai uji hedonik yang menunjukkan penerimaan yang baik pada warna, aroma, tekstur, rasa, dan keseluruhan serta nilai cerna protein 43,26%.
KARAKTERISTIK SEREAL FLAKES TEPUNG PRA-MASAK JEWAWUT, TAPIOKA, KACANG TUNGGAK, DAN IKAN LELE SEBAGAI SARAPAN SEHAT
Authors: Mulyani Dwi  , Rosida  , Yunita Satya Pratiwi
Published: February 2025

Flakes merupakan makanan siap saji yang berpotensi sebagai alternatif menu sarapan yang dapat memenuhi kebutuhan kalori. Penelitian ini bertujuan untuk menganalisis pengaruh perlakuan proporsi tepung pra-masak jewawut dan tapioka serta  proporsi tepung kacang tunggak dan tepung ikan lele terhadap sifat kimia, fisik, dan organoleptik flakes. Metode penelitian yang  digunakan adalah Rancangan Acak Lengkap (RAL) dengan pola faktorial yang terdiri dari 2 faktor dengan ulangan sebanyak 2 kali. Faktor I adalah prorosi tepung pra-masak jewawut dan tapioka (75:25; 80:20; 85:15) dan faktor II adalah proporsi tepung kacang  tunggak dan tepung ikan lele (65:35; 75:25; 85:15). Data yang dihasilkan dianalisa dengan ANOVA taraf 5% dengan uji lanjut  Duncan (DMRT) jika terdapat interaksi yang nyata (P≤0,05). Perlakuan terbaik pada penelitian ini yaitu flakes dengan proporsi  tepung pra-masak jewawut dan tapioka (85 : 15) serta proporsi tepung kacang tunggak dan tepung ikan lele (85 : 15) yang memiliki  kadar air 3,84%, abu 2,68%, lemak 5,76%, protein 8,38%, karbohidrat 79,34%, pati 42,17% daya rehidrasi 84,95%, daya patah 9,5 N, serta uji organoleptik meliputi rasa 3,8 (netral), aroma 3,36 (netral), warna (3,6) netral, dan kerenyahan 4,16 (suka), daya cerna  protein 74,61%, daya cerna pati 62,52%, serat pangan 7,04%, dan total kalori 452,9 kal.
PENGARUH BERBAGAI METODE PENGERINGAN TERHADAP FISIKOKIMIA BUBUK CABAI : STUDI PUSTAKA
Authors: Muhammad Rahmad Ramadhan  , Desta Ria Erika  , Andi Dahlan
Published: February 2025

Bubuk cabai merupakan salah satu cara dalam mengawetkan cabai segar melalui berbagai tahapan seperti pengeringan dan penggilingan hingga menjadi serbuk. Review ini membahas pengaruh berbagai metode pengeringan terhadap fisikokimia bubuk cabai yang dihasilkan. Selain itu, review ini juga bertujuan untuk mengulas berbagai penelitian yang telah dilakukan mengenai pengaruh berbagai metode pengeringan terhadap fisikokimia bubuk cabai. Melalui kajian pustaka ini diharapkan dapat menjadi sumber informasi tentang metode pengeringan yang optimal dalam mempertahankan kualitas bubuk cabai. Metode pengeringan yang umum digunakan yaitu sinar matahari yang memiliki kelemahan karena menghasilkan produk dengan mutu yang buruk, pengeringan yang tidak merata, memerlukan waktu yang lama untuk menurunkan kadar air dan dipengaruhi oleh faktor cuaca yang tidak menentu. Kajian mengenai pengaruh berbagai metode pengeringan terhadap fisikokimia bubuk cabai dapat memberikan wawasan penting dalam memilih metode yang tepat agar meminimalkan penurunan kandungan gizi dan menghasilkan bubuk cabai yang berkualitas baik. Metode pengeringan tidak hanya terbatas pada penggunaan sinar matahari, tetapi juga melibatkan berbagai metode lain seperti cabinet dryer, hot-air dryer, solar dryer, gas oven, dan freeze drying. Kajian terhadap hasil fisikokimia bubuk cabai yang menggunakan cabinet dryer, solar dryer, dan gas oven menunjukkan bahwa metode tersebut mampu memenuhi syarat kualitas dengan kadar air ≤ 10% dan kadar abu ≤ 8%. Selain itu, jika dibandingkan pengeringan menggunakan sinar matahari terutama dalam kondisi optimal yang mencakup pengunaan suhu dan waktu metode pengeringan seperti cabinet dryer, solar dryer, dan gas oven lebih efisien.
Caso clínico MIR. Haz tu diagnóstico. Neuropatía periférica progresiva y simétrica en un adolescente
Authors: Servitje Verdaguer B , Pérez Moreno R , Olivé Cirera G , Conti Degiorgis R
Published: February 2025

Exponemos el caso de un niño de 13 años que consultó en varias ocasiones en Urgencias por dolor en los pies bilateral, de características urentes y fluctuantes, con mala respuesta a la analgesia oral, que progresó hasta presentar una distribución en guante y calcetín.
Patología de la vía biliar
Authors: Lledín Barbancho María Dolores , Quiles Blanco María José
Published: February 2025

La patología de la vía biliar en la edad pediátrica es muy poco frecuente. Se trata de un grupo muy amplio y heterogéneo de entidades (Tabla I), para muchas de las cuales no disponemos de un tratamiento médico eficaz que cambie el curso natural de la enfermedad. En algunas patologías es fundamental el diagnóstico rápido, ya que la demora puede suponer un rápido deterioro del paciente, en ocasiones, con daños irreversibles. En este capítulo se han clasificado según su patogenia en: 1) colangiopatías debidas al daño inflamatorio en los conductos biliares por la activación de los colangiocitos por múltiples estímulos, centrándonos en la atresia de vías biliares; 2) alteraciones en la embriología de la vía biliar que originan vías biliares anómalas, con escasez ductal como dato predominante, como en el síndrome de Alagille, o con fibrosis peribiliar y formación de quistes a diferentes niveles del árbol biliar que caracterizan a las enfermedades hepáticas fibroquísticas; y 3) obstrucción de la vía biliar por cálculos biliares, una patología cada vez más diagnosticada, debido al número creciente de ecografías abdominales realizadas en la población infantil por otros distintos motivos.
The Concept of Al-'Ilm Al-Ushuliy: The Significance of Ushul Al-Fiqh in the Paradigm of Unity of Science
Authors: Majid Ilham
Published: February 2025

This research explores the significance of ushul al-fiqh within the paradigm of the unity of knowledge (Unity of Science), focusing on the integration between Islamic law and other sciences. The main concern is how ushul al-fiqh can provide a holistic theoretical foundation for religious values such as wisdom, justice, and public welfare in everyday life. This study employs a qualitative method with a descriptive-analytical approach, utilizing a literature review to explore the meaning, perception, and complex context within a research framework. Key findings indicate that ushul al-fiqh plays a crucial role in understanding the fundamentals of Islamic law and integrating religious aspects, reason, and practical experience in life. This research aims to identify and analyze the principles of ushul al-fiqh that can support the integration of various scientific disciplines and assess their relevance in contemporary knowledge. The unity of knowledge in this research refers to efforts to amalgamate various disciplines into an interconnected entity. This involves integrating Islamic law (ushul al-fiqh) with other sciences, such as logic, Arabic grammar, theology, jurisprudence, and Qur'anic and Hadith studies. In this context, the unity of knowledge aims to create coherence among various branches of knowledge to provide a holistic understanding of religious values such as wisdom, justice, and public welfare in everyday life.
Entrepreneurship Education Management in Enhancing the Entrepreneurial Competence of Students at Pondok Pesantren Fathul Ulum
Authors: Shobirin Mochammad Syafiuddin , Masrokan Prim , Fuadi Imam
Published: February 2025

The implications for the entrepreneurial competence of students at Pondok Pesantren Fathul Ulum can be identified through research encompassing the planning, implementation, and evaluation of entrepreneurship education. The research method employed is qualitative with a phenomenological approach, utilizing in-depth observation, interviews, and documentation for data collection. SWOT analysis is used as the analytical technique. The validity test employs source triangulation and technique triangulation methods. The research results indicate that the planning of entrepreneurship education at Pondok Pesantren Fathul Ulum is incorporated into an entrepreneurship learning curriculum consisting of theory- and practice-based learning plans. Entrepreneurship education is conducted using two methods: theory-based learning and practice-based learning. Entrepreneurship education achievement is evaluated through two direct methods (learning process) and post-learning. The evaluation of entrepreneurship education learning uses the CIPP (Context, Input, Process, and Product) evaluation model. The entrepreneurial competence of students at Pondok Pesantren Fathul Ulum is designed to develop social and corporate entrepreneurship competencies. The management of entrepreneurship education has implications for students' acquisition of knowledge, skills, and attitudes, aiming to equip them with the ability and competence to become initiators in entrepreneurship.
ANÁLISE DEMOGRÁFICA E EPIDEMIOLÓGICA DE ÓBITO POR CIRROSE HEPÁTICA: DELINEAMENTO TEMPORAL
Authors:   Jadsonn Souza De Melo, Pereira Higor Fernandes , Ferreira Neto Antônio Custodio , Laurindo Filho José Joaquim , Araújo Isadora Wanderley , Borges Maria Clara Machado , Oliveira Kaio Gabriel Lopes Gonçalves De , Bezerra Ingrid Matos , Silva Murilo Rodrigues Da , Grangeiro Rafael Sampaio Luna
Published: February 2025

Introdução: A cirrose hepática é uma condição crônica que representa um desafio significativo para a saúde pública global, dada a sua alta morbimortalidade e impacto econômico. No Brasil, os fatores predominantes associados ao desenvolvimento da cirrose incluem o abuso de álcool, hepatites virais e a doença hepática gordurosa não alcoólica (DHGNA). Objetivos: Descrever o perfil e taxa de óbito por cirrose hepática nos anos de 2019 a 2023 no Brasil. Método: O estudo adotou um delineamento retrospectivo, descritivo e quantitativo, utilizando dados secundários extraídos do Sistema de Informações sobre Mortalidade (SIM), disponível no DATASUS. A amostra incluiu todos os registros de óbitos por cirrose hepática no Brasil, entre 2019 e 2023. As variáveis analisadas foram sexo, faixa etária, cor/raça, estado civil, região geográfica de residência e ano do óbito. A análise dos dados foi realizada por meio de técnicas estatísticas descritivas, com o uso de gráficos e tabelas para a interpretação dos resultados. Resultados: Foram registrados 47.444 óbitos por cirrose hepática no período analisado. A maior prevalência de mortes ocorreu entre homens (71,01%) e em indivíduos com idades entre 55 e 74 anos. A Região Sudeste concentrou a maior proporção de óbitos (51,07%), seguida pela Região Nordeste (19,87%). Os anos de 2021 (10.072 óbitos) e 2022 (9.592 óbitos) apresentaram os maiores registros de mortalidade. Conclusão: A cirrose hepática continua a ser uma importante causa de morte no Brasil, com uma alta incidência nas faixas etárias mais avançadas e predominância masculina. A variação nas taxas regionais reflete desigualdades no acesso ao cuidado e nas prevalências de fatores de risco.
Hemoglobin Level Examination in Students of Panrita Husada Bulukumba Health College Who Consume Instant Noodles
Authors: Hasanuddin AR Pratiwi , Rifky Andi Aidar , Fatimah Fatimah
Published: February 2025

Hemoglobin is an iron-rich protein in red blood cells responsible for oxygen transport from the lungs to body tissues. Iron, along with vitamin B12 and folic acid, is essential for hemoglobin formation, with iron being a key component in heme production. Consuming instant noodles more than twice a week can increase the risk of metabolic disorders, such as obesity, high blood pressure, elevated blood sugar, and cholesterol. This study aimed to assess the hemoglobin levels of STIKES Panrita Husada Bulukumba students who consume instant noodles regularly. A descriptive cross-sectional quantitative study was conducted with 25 respondents. The results revealed a range of hemoglobin levels, with a low value of 8.0 g/dl, a normal value of 13.1 g/dl, and a high value of 16.1 g/dl, with a standard deviation of 2.04. The study found significant variation in hemoglobin levels among the students, with some indicating potential anemia and others suggesting polycythemia. This supports previous studies linking regular instant noodle consumption to malnutrition, particularly iron deficiency anemia.
Clinical, Bacteriological And Radiological Profile Of Patients With Community Acquired Pneumonia In A Tertiary Care Hospital In South India
Authors: Kumar Dr. M. Sathish , Pranavi Dr.
Published: February 2025

BACKGROUND: Pneumonia is one of the most common infections encountered in the clinical practice. Despite being the cause of significant mortality and morbidity, pneumonia is often misdiagnosed and mistreated. Pneumonia is defined as inflammation and consolidation of lung tissue due to an infectious agent. Pneumonia that develops outside the hospital is considered community acquired pneumonia (CAP).OBJECTIVE: To study the clinical, radiological, and bacteriological profile of patients with community- acquired pneumonia To evaluate CURB- 65 scoring system in community acquired pneumonia in tertiary care hospital.MATERIAL AND METHOD: This study was done in DEPARTMENT OF RESPIRATORY MEDICINE, TAGORE MEDICAL COLLEGE AND HOSPITAL, CHENNAI, TAMILNADU. The period of data collection was from January 2023 to December 2023. Eighty one patients were included in the study. A detailed history and examination, chest x-ray, routine laboratory investigation and sputum culture was done for all the patients diagnosed with community acquired pneumonia. CURB65 scoring system were applied to all the patients included in this study to assess the severity and prognosis.RESULTS: In the study it was observed that most of the patients were among 56 to 65 years of age group. The disease occurrence was more common in males. In the present study all the patients were symptomatic. The most common presenting symptom was cough and fever, followed by breathlessness(40. 7%), chest pain (22.2%) and confusion ( 3.7 %). Fever was equally distributed among both the age group. But cough and breathlessness was more among the older age group. The most common risk factor was smoking (43.2%) and alcohol intake (40 .7 %). The co-morbidities diabetes ( 29. 6%) and COPD (24.7 %) were seen predominantly in these patients. Streptococcus pneumonia( 38. 3%) was the most common etiological agent identified through sputum culture followed by gram negative organism (klebsiella and pseudomonas). Radiologically, the lower lobe was more commonly involved followed by middle lobe. There was no correlation between the causative agent and radiological appearance. The rate of ICU admission was 14%. Two patients in our study had died. CURB 65 was applied to all the patients and CURB 65 proved to be a good prognostic indicator for assessing the severity of community acquired pneumonia.
Nutritional and functional properties of eleven hybrid and land-race rice varieties from Assam, India
Authors: Sharma S.K. , Mali Nilpawan , Sharma R.K. , Barman D.
Published: February 2025

Rice is one of the most important food crop in the world which provides a primary source of dietary energy, particularly in Asia. It is a flexible and health-promoting staple due to its nutritional richness in carbohydrates, protein, and other essential phytochemicals. This study investigates the proximate composition, functional properties, and biochemical characteristics of eleven rice cultivars from Dhubri district, Assam. Key findings indicate that varieties such as Rupahi, Bahadur Sub-1, Lalpeda, Geda Gedi, Ranjit Sub-1, and Natun Aijong exhibit superior qualities in various parameters. Proximate analysis reveals that the Lalpan variety exhibits the highest fat content (4%), Kola Mota has the highest crude fiber content (2.80%), Bahadur Sub-1 contains the highest protein content (13.77%), Natun Aijong has the highest carbohydrate content (86.54%), and Chapar Aijong shows the highest food energy value (412.1 kcal). In functional properties, Lalpeda demonstrates the highest water absorption capacity (1.2506 g/L) and water solubility index (0.0933 g/L), while Geda Gedi has the greatest swelling power (0.0114). The highest oil absorption index is found in Bahadur Sub-1 (0.348). Additionally, Lalpeda shows the highest total phenolic content (0.0024 μg/mg), Rupahi has the highest total flavonoid content (13.59 mg/g) and amylase content (18.76%), while Natun Aijong has the highest starch content (77.88%). Among all varieties, Rupahi and Bahadur Sub-1 consistently demonstrate enhanced nutritional and functional attributes, identifying them as promising candidates for both cultivation and commercial applications. This research contributes valuable insights into the nutritional diversity of Assamese rice landraces.
Clinical Evaluation of Laghu Shankha Prakshalana in The Management of Madhumeha (Diabetes Mellitus-II): A Case Report
Authors: . Sonika , . Kapil , Chowdhury Dr. Kanchan , Srivastava Dr. Vijay Kumar
Published: February 2025

Diabetes is a chronic noncommunicable disease for which there is not yet a cure. Diabetes mellitus-II (DM) is a group of metabolic disorders characterized by chronic hyperglycemia due to relative insulin deficiency, resistance, or both, resulting in abnormally high blood glucose levels and many complications. Madhumeha described in Ayurveda texts is often compared with Diabetes mellitus-II. Yoga, an ancient practice, is now emerging as a complementary therapy for noncommunicable diseases such as hypertension, diabetes, etc. In the present case study, a 54-year-old female patient with a known case of Madhumeha (Diabetes Mellitus-II) for the past one year presented with complaints of increased frequency of urination, stress, burning sensation in hands and feet, excessive sweating, hunger, thirst, and fatigue. A properly designed three-month Yoga Practice was provided to her by Yoga trainer. After three months, fasting blood sugar dropped from 136 to 95 mg/dL and postprandial blood sugar dropped from 221 to 110 mg/dL, and Weight is reduced from 80 to 70 kg. The subjective symptoms also decreased remarkably. The results concluded that consistent long-term practice of Yogic Practices can not only maintain the blood sugar levels of patients with diabetes but also improve the quality of life
The Role Of Academic Flow In The Academic Achievement Of Secondary School Students
Authors: Pilla Syamala , Chakraborty Dr. Rajib
Published: February 2025

The concept of learning flow plays a crucial role in influencing academic achievement. When students encounter challenging tasks, experiencing frustration can hinder their ability to effectively engage with their studies. Without a productive learning process, students may struggle to meet academic expectations, which can lead to disengagement or even dropout. Therefore, fostering a positive learning flow is key to overcoming obstacles and promoting persistence. The pursuit of academic excellence remains a central goal for students, as it not only shapes their educational journey but also unlocks future career opportunities and contributes to personal growth. Flow, often described as a state of intense focus and immersion in a task, has become a critical factor in determining academic success. When students enter this state, they are able to push through difficulties and perform at their highest potential, ultimately enhancing both their educational outcomes and overall well-being. The study sample comprised secondary school students enrolled in CBSE schools under the Central Government in the Vijayawada region, Krishna District, Andhra Pradesh. A total of 1000 of 9th-grade students were selected, representing both rural and urban areas within the district. The findings indicated that there is a positive correlation between Academic Flow and Academic Achievement among secondary school students.
Deceased Donor Renal Transplantation: Our Experience at a Tertiary Care Centre in Karnataka, India
Authors: BR Dr Ravikumar , Gowda Dr Amruthraj G , Jaiswal Dr Karan , A Dr Shalini
Published: February 2025

Introduction and Objective: End-stage renal disease (ESRD) causes renal failure requiring renal replacement therapies like dialysis or transplantation. [1] With the increasing incidence of diabetes, hypertension and aging population ESRD prevalence is rising [2]. In India, 1,75,000 ESRD patients are added every year out of which only 10% receive renal replacement therapy and 2.4% undergo transplantation. Due to limited live donor pool and stringent rules on unrelated donors there is a significant organ shortage. Deceased Donor Renal Transplantation (DDRT) is an effective solution for bridging the gap in demand and supply [4]. This paper presents our five-year DDRT experience (Jan 2019 – Sept 2024), analysing demographics, outcomes and various other factors highlighting the need to expand DDRT to meet rising demand of renal transplantation among ESRD patients, especially without a live related donor.Methods: A retrospective study was done, and data was compiled and analysed of 32 recipients who underwent deceased donor renal transplantations done between January 2019 – September 2024 under the Department of Urology at our centre. Various donor and recipient characteristics were analysed with other factors affecting the outcome of deceased donor renal transplantation, postoperative complications along with graft and patient survival.Results: The mean recipient age was 45 ± 11 years and donor age was 39 ± 12 years, with 31% of recipients and 22% of donors being female. Chronic interstitial nephritis was the primary cause of ESRD, followed by chronic glomerulonephritis. All patients received preoperative induction with anti-thymocyte globulin (ATG) and postoperative immunosuppression with a Tacrolimus-based regimen. The mean cold ischemia time (CIT) was 573 ± 217 minutes, with CIT >600 minutes showing a statistically significant association with delayed graft function (DGF) and acute rejection (p = 0.038). DGF occurred in 47% of patients, while acute rejection affected 18%, with antibody-mediated rejection (ABMR) as the predominant type (50%). Graft nephrectomy was required in 12.5% of cases, primarily due to ABMR. Post-transplant mortality was 18.8%, mainly due to sepsis and cardiovascular events. Patient survival rates were 76% at 1 year and 73.3% at 2 years, while graft survival was 72% at 1 year and 66.6% at 2 years. Kaplan-Meier analysis showed mean patient survival of 46.6 ± 4.8 months and mean graft survival of 51.6 ± 3.8 months.Conclusion: Our study highlights the effectiveness of DDRT at our centre, with favourable patient and graft survival rates. Our study also concludes that DDRT is an excellent alternative to fill the organ shortage by increasing the donor pool for renal transplantation and improve the outcome and QOL of ESRD patients especially without a live related donor awaiting transplantation.
Bacopa Monnieri Bacterial Endophytes: Regulating Plant Growth And Active Phytochemicals
Authors: . Himani , Kumar Vijay , Sharma Charu , Rawat Geeta , Naik Bindu , Rajput Vishal , Gupta Sanjay , Kumar Vivek
Published: February 2025

The alteration of rhizospheric and endophytic diversity of microorganisms are of increasing attention as shift in microbic community structure influences the reciprocal function of host-microbiome relations. The present study investigates the previously unexplored dominion of endophytic bacterial partners of medicinal plant Bacopa monnieri and discloses their crucial function in endorsing plant growth and biosynthesizing active phyto-ingredients. Two bacterial isolates (Achromobacter denitrificans and Shinella oryzae) were selected and identified using phenotypic and and molecular characterization from an extensive collection of bacterial isolates. The synergetic potential of bacterial endophytes was validated by the noted growths in B. monnieri's shoot and root length after inoculation. On the basis of LC-MS analysis, several active phyto-ingredients, such as bacopaside I, II, brahmic acid, epigenin, eblin, and stigmasterol, were observed in appreciably higher content in endophytes inoculated treatments. These phytochemicals were detected in an experiment conducted in sterile soil, emphasizing the intricate interactions between host plant and bacterial endophytic community. This report first time mention the role of endophytic bacteria Achromobacter denitrificans and Shinella oryzae in enhancing the B. monnieri plant growth and active ingredients. This pioneering unearthing brings up new prospects for sustainable agriculture and pharmacological improvement as well as revealing the previously unidentified potential of B. monnieri's endophytic associates.
Efeitos do uso crônico de anti-inflamatórios não esteroides na saúde renal e cardiovascular
Authors: Avelar Mariana Lívia Sevirino , Neves Vitória Carvalho , Ganem Vitor Ramos Ali , Dias Leandro de Araújo Rios Teixeira
Published: February 2025

Os anti-inflamatórios não esteroides (AINEs) são amplamente utilizados para o manejo da dor e inflamação, mas seu uso crônico está associado a riscos renais e cardiovasculares significativos. A inibição das ciclooxigenases compromete a perfusão renal, levando à redução da taxa de filtração glomerular, lesão renal aguda e progressão para doença renal crônica. Além disso, os AINEs podem induzir disfunção endotelial e promover um estado pró-trombótico, aumentando o risco de infarto agudo do miocárdio e acidente vascular cerebral. A minimização desses riscos exige uma abordagem individualizada, baseada na restrição da duração do tratamento, na escolha criteriosa do fármaco e no monitoramento laboratorial contínuo. Alternativas terapêuticas, incluindo paracetamol, opioides e estratégias não farmacológicas, podem ser adotadas para reduzir a dependência dos AINEs. Profissionais da saúde devem considerar fatores de risco individuais e adotar um modelo terapêutico personalizado para otimizar a segurança e eficácia do tratamento da dor.
Artificial Intelligence in Aviation: A Review of Machine Learning and Deep Learning Applications for Enhanced Safety and Security
Authors:   Air University, Islamabad, Pakistan, Ahmed Waqas
Published: February 2025

Artificial intelligence (AI) transforms aviation, driving new, safe, and secure solutions. In this review, we dive into the transformative role that machine learning and deep learning play in critical aviation applications, such as predictive maintenance, anomaly detection, flight path optimization, and pilot assistance. AI-driven systems use real-time data to predict equipment failures and speed deviation from normal flight behavior and to optimize resource management to improve operational efficiency. AI helps strengthen cybersecurity in aviation security, enhances the accuracy of passenger screening, and boosts air traffic management with predictive analytics. There has been a lot of progress already, but data quality, scalability, governing frameworks, and ethical concerns are some factors that make widespread adoption a challenge. Further advances are anticipated in the coming years due to emerging trends like explainable AI, quantum computing, and collaborative AI. The lesson that this study illustrates is that there remains much work to be done to ensure that the full potential of AI can be used to deliver safer, more secure, and faster air travel.
Risk Factors Associated with Acute Respiratory Distress Syndrome in Pediatrics
Authors: Dilawar Abbas Awan  , Zubair Sharif  , Usra Naeem  , Taseer Batool  , Ghalib Habib  , Kiran Shahzadi
Published: February 2025

Background: Every expectant mother hopes for a healthy baby, yet complications during delivery can lead to severe conditions like acute respiratory distress syndrome (ARDS). This study aims to identify key risk factors associated with ARDS in pediatric patients. Methodology: A questionnaire was developed through a literature review to identify key ARDS risk factors in pediatrics. The questionnaire was verified by a panel of pediatric experts, and its reliability was tested (Cronbach’s alpha = 0.5). Results: Among the infants, 55% were male and 45% female. APGAR scores showed 36% had mild depression, 46% moderate, and 18% severe asphyxia. Mechanical ventilation was required for 40% of patients. Preterm births accounted for 67.13% of cases, while 64.3% were term and 8.4% late-term. C-section deliveries were common (65.03%), and 41% of patients had raised bilirubin levels. Only 20% were breastfed, while 58% required nasogastric tubes. Most patients (81.82%) were aged 1 day to 1 month. Hospital stays varied: 35% in days, 46% in weeks, and 19% in months. Advanced Cardiac Life Support was needed for 29%, and blood transfusions for 24%. Ventilator modes varied, with nasal cannula (45%) being the most used. PaO₂/FiO₂ ratios were normal in 29%, mild in 33%, moderate in 21%, and severe in 17%. Mortality was 24%. Conclusion: Preterm birth and mechanical ventilation were the major risk factors for pediatric ARDS. Sepsis, HIE II & III, pneumonia, metabolic disorders, and meconium aspiration were prevalent diagnoses.Surfactant therapy was associated with a 68% mortality rate, emphasizing its impact on lung maturity.
Effect of Heat Stress on Various Physiological Activities and Especially on Reproductive Performance in Dairy Animals
Authors: Kamran Ahmad Nasir  , Sohail Ahmad  , Haider Zaman  , Syeda Umm e Farwa Kazmi  , Hafiz Aftab Jan  , Imtiaz Ahmed Cheema  , Muhammad Jafir Muneer  , Muhammad Munir Khan  , Umair Ahmed  , Sardar Zarq Khan
Published: February 2025

This study examined the effects of heat stress on the physiological functions and reproductive performance of dairy cows, emphasising the influence of cooling techniques, dietary interventions, and exposure to heat stress. This study employed a randomised controlled trial (RCT) methodology, involving two groups of dairy cows subjected to either heat stress conditions (30–35°C and 70–85% humidity) or thermoneutral settings (18–22°C and 45–55% humidity) conducted at UVAS, Lahore. Both groups received conventional or high-energy foods together with cooling measures (fans, misters, and shade). Physiological indicators, such as cortisol levels, body temperature, and respiration rates, were assessed in conjunction with oestrus cycles, ovulation rates, and pregnancy outcomes. The results indicated that heat stress markedly diminished milk production and reproductive health, characterised by prolonged estrous cycles, decreased ovulation rates, and lower pregnancy rates in the heat stress cohort. Cooling systems and nutritional techniques alleviated certain adverse effects; however, heat stress resulted in inferior outcomes relative to the control group. These results provide significant insights into how integrated management techniques can enhance dairy output and fertility rates under heat-stressed conditions. The research yielded substantial implications for dairy production operations, particularly in tropical and subtropical locations, where heat stress is a considerable issue. Future studies should focus on longitudinal studies regarding the effects of heat stress and genetic adaptation in dairy cattle, in addition to exploring the practical uses of cooling and nutritional therapies.
Cognitive Dissonance Among Retail Investors Dealing in Equity Market
Authors: Joshi Sanjay ,   SDJ International College, Palsana, Chaudhari Jaydip ,   Veer Narmad South Gujarat University
Published: February 2025

The study aimed to identify the factors affecting pre-buy/sell confusion and post-cognitive dissonance among investors in equity shares dealing and to identify dissonance reduction strategies adopted by investors to reduce their dissonance in equity shares dealing. ‘Descriptive –Single Cross-Sectional’ research design has been used in this study. Primary Data was collected using the Survey method (Structured Questionnaire) of respondents (Investors) of significant areas of Surat city. Generally, these data types are gathered from numerous sources such as books, past studies, and websites. 140 sample sizes were considered and extracted through the NonProbability Sampling Method – Convenience and Snowball Sampling. Data was collected from investors participating in the equity market who are active investors and not traders. In conclusion, three major confusion factors were identified: Product/Service Overload Confusion, Ambiguity and Overloaded/Fake Information Confusion. Moreover, four prominent factors for cognitive dissonance arise: dissonance, choice-based dissonance, dissonance reduction, and action-based dissonance. Further, the dissonance reduction strategies mostly prevailing among Surat investors are affirmative consonance, confirmatory consonance and negative word-ofmouth.
A Detailed Study on Measuring the Effectiveness of Women Entrepreneurship Training and Skill Development Program
Authors: Sami Sania ,   Indian Institute of Social Welfare and Business Management, Roychowdhury S. ,   Indian Institute of Social Welfare and Business Management
Published: February 2025

India has prioritized the development and fostering of entrepreneurship across states. Further, the COVID-19 pandemic has shown a plunge in many home-based women entrepreneurs, a new trend that will continue to grow. Thus, the entrepreneurial training program is mushrooming by government and non-government institutions. This study aims to measure the effectiveness of one such training program. The study includes both existing and potential women entrepreneurs. Many studies highlighted the significance of the entrepreneurship training program, but it is also essential to investigate the effectiveness of such a program. Thus, the principal aim of this study was to measure the effectiveness of one such women’s entrepreneurial training program. The findings of this study measure the effectiveness of one of such training programs and provide a framework for future training programs. The training effectiveness was evaluated using Kirkpatrick’s 4-level training evaluation model. In this study, training effectiveness was measured at two levels. This empirical study recognizes the effectiveness and level of business skills acquired by the women trainees. The study also identifies the scope and areas for future research.
Exploring the relationship between library resources and students’ academic performance
Authors: Dr. Abid Ali  , Rafeeudin  , Imran Khan Imran Khan , Dr. Ihsan Ullah Khan Dr. Ihsan Ullah Khan
Published: February 2025

Libraries play a crucial role in supporting students' academics by granting them access to a variety of information and services to enhance their academic performance. This study aims to explore the impact of library resources on the college student’s academic performance. This research targeted 1641 BS-level students enrolled in the spring semester of 2023. Employing a simple random sampling, a sample of 311 students was selected based on the Sekaran table (2003). Descriptive statistics indicated that students extensively utilized the library for studying, as reflected by a high mean score (M=2.93) for library utilization. Additionally, personal study environment (M=2.73), study habits, and resources (M=3.49) received notably high mean scores. Correlation results demonstrated a positive and significant relationship (r=.576, p=.000) between the library and student academic performance. Specifically, the correlation between student academic achievement and library use was found strongly significant (r=.674, p=.000), indicating a clear association between these variables. However, no significant correlation was observed between student academic performance and the personal study environment in this study (r=.558, p=.021). Conclusively, this research indicates that colleges ought to give precedence to digital library services and guarantee that learners have access to course-specific resources, thereby creating a basis for improving students' knowledge.
Translating through Ups and Downs — A Critical Review of Creation and Restriction: Factors That Affect Translation
Authors: Chen Grace
Published: February 2025

Creation and Restriction: Factors That Affect Translation by Prof. Deng Di is a comprehensive scholarly work that explores the multifaceted constraints influencing the translation process. Published by Routledge in 2024, the book integrates insights from linguistics, literature, culture, and society, offering a systematic analysis of translation constraints at micro, meso, and macro levels. The book excels in its theoretical rigor, particularly in its balanced approach to internal and external constraints, and its focus on the cognitive processes of translators. However, it falls short in providing practical guidance for translators, limiting its applicability for practitioners. Despite this, the book makes a significant contribution to translation studies, bridging gaps between theory and practice, making it a valuable resource for scholars and advanced students in the field.
Analysis of the Effectiveness of Flow 3D Cast Software in Optimizing the A356 Casting Process
Authors: Arif Joni , Mujiyono Mujiyono , Tiwan Tiwan
Published: February 2025

A356 aluminum alloy casting is one of the manufacturing methods widely used in the automotive and aerospace industries because it has superior mechanical properties and good corrosion resistance. However, this casting process often faces technical challenges, such as porosity, shrinkage, and defects due to suboptimal metal flow. Therefore, Flow-3D Cast, a software based on Computational Fluid Dynamics (CFD), is used to optimize the casting process by simulating the flow of molten metal, solidification analysis, as well as temperature distribution in the mold. This study aims to evaluate the effectiveness of Flow-3D Cast in optimizing the casting of A356, with a focus on reducing casting defects, increasing production efficiency, and improving the design of the gating and riser system. The research method used is a literature study by analyzing various previous research results that discuss the application of Flow-3D Cast simulation in optimizing the A356 casting process. Data is obtained from indexed scientific journals, academic books, and relevant technical reports. The results show that the use of Flow-3D Cast can reduce shrinkage defects by up to 40%, improve the homogeneity of microstructures, and optimize the flow rate of molten metal in the mold. In addition, the design of the gating system that has been optimized through simulation has been proven to be able to increase casting yield by up to 85% and reduce energy consumption in the casting process. Thus, the use of Flow-3D Cast-based simulation has proven to be effective in improving the quality of A356 casting products, reducing production defects, and reducing operational costs in the foundry industry.
Moral Responsibility in the Development of Artificial Intelligence according to Ethical Theology
Authors: Kesumawati Kesumawati , Lombok Jan Lukas Lambertus , Harefa Otieli
Published: February 2025

The development of artificial intelligence (AI) has brought about various significant changes in various sectors of life, including industry, education, and health. However, advances in AI also pose moral and ethical challenges, especially related to transparency, fairness, and accountability in their use. In the context of ethical theology, moral responsibility in the development of AI is an important aspect that needs to be considered to ensure that this technology is developed and applied responsibly in accordance with applicable human values and moral principles. This research aims to examine how the principles of ethical theology can provide a normative foundation in the development of more ethical and responsible AI. The method used in this study is a literature study by analyzing various academic sources, including scientific journals, books, and policy documents that discuss the relationship between AI, morality, and ethical theology. The data collected were then analyzed using the qualitative content analysis method to identify the main findings in this study. The results of the study show that the development of ethical AI requires the integration of moral principles such as justice, love, accountability, and respect for human dignity. Additionally, human regulation and oversight remain necessary to ensure that AI is not used in a way that harms certain individuals or groups. Therefore, the ethical theology approach can be one of the solutions in formulating a more equitable and responsible AI policy.
Pengeluaran Pemerintah Pendidikan dan Kesehatan Terhadap Pertumbuhan Ekonomi Provinsi Sumatera Selatan
Authors: Panisah  , Muhammad Yusuf  , Shoofiyah Maharani  , Salwa Aliyah Kamilah  , Muhammad Ambiya Abid  , Ardian Narendra Maulana
Published: February 2025

Investasi di bidang pendidikan dan kesehatan tidak hanya bersifat jangka panjang, tetapi juga menjadi dasar untuk meningkatkan kualitas sumber daya manusia yang berperan langsung dalam produktivitas ekonomi. Penelitian ini bertujuan untuk mengevaluasi dampak belanja pemerintah di sektor pendidikan dan kesehatan terhadap pertumbuhan ekonomi di Provinsi Sumatera Selatan, Penelitian ini bertujuan untuk memberikan pemahaman yang lebih mendalam mengenai keterkaitan antara investasi pemerintah di sektor pendidikan dan kesehatan serta pengaruhnya terhadap pertumbuhan ekonomi daerah. Penelitian ini menggunakan pendekatan kuantitatif dengan menerapkan analisis regresi linier berganda, dengan memanfaatkan data sekunder mengenai Belanja pemerintah di sektor pendidikan dan kesehatan di Sumatera Selatan dari tahun 2021 hingga 2023 data ini diperoleh dari Badan Pusat Statistik (BPS) Provinsi Sumatera Selatan. Hasil riset mengindikasikan bahwa belanja di bidang kesehatan, dengan nilai signifikansi 0,005, memberikan dampak positif yang signifikan terhadap pertumbuhan ekonomi. Sebaliknya, alokasi dana untuk sektor pendidikan tidak memberikan dampak berpengaruh signifikan terhadap pertumbuhan ekonomi, dengan tingkat signifikansi sebesar 0,274.
Real-World Outcomes of Single-Inhaler Triple Therapy Prescribed by General Practitioners in Managing Chronic Obstructive Pulmonary Disease: A Systematic Literature Review
Authors: Odonde Linet , Pradelli Lorenzo , Micheletto Claudio
Published: February 2025

BACKGROUND: The benefits of triple therapy for Chronic Obstructive Pulmonary Disease (COPD) have been established in two 52-week phase-3 randomized controlled trials. The current systematic literature review (SLR) appraised available evidence on the real-world outcomes of single-inhaler triple therapy (SITT) when prescribed by general practitioners (GPs).METHODS: Using the PICOS (Population, Intervention, Comparator, Study design) framework, a literature search was conducted to identify suitable studies for the review. PubMed and Embase databases were searched, and Rayyan was used to screen articles for inclusion. The study selection followed the Preferred Reporting Items for Systematic Reviews andMeta-Analysis guidelines.RESULTS: 1,379 non-randomized clinical studies published between 2020 and 2024 were identified from the literature search. 1,367 articles were later excluded from the review (duplicates: n = 119; not eligible: n = 1,248), leaving 12 studies for inclusion. 10 studies were single-armed, while 2 were comparative. 7 studies were from Germany, 3 from the United Kingdom, and 1 each from France, Greece, and Belgium. The SITT combinations studied were beclomethasone dipropionate/formoterol fumarate/glycopyrronium bromide (n = 9) and fluticasone furoate/umeclidinium bromide/vilanterol (n = 3). One study did not specify this. One study reported on inhaler use, 8 on adherence, 2 on drug persistence, 5 on lung function, 3 on exacerbations, and 6 on health-related quality of life.CONCLUSIONS: We found evidence of possible benefits for SITT prescribed by GPs on real-world outcomes. Nevertheless, the evidence is limited in quantity and quality, and future real-world studies need to confirm our findings.