bluuebunny/crossref_metadata_2025 huggingface dataset:
Les programmes d’activité physique en entreprise : la nécessité d’une approche pluridisciplinaire
Authors: ESSAFI Mokhtar , BARGET Éric
Published: March 2024

Depuis l’introduction du modèle taylorien de l’Organisation scientifique du travail (OST) à la fin du 19e siècle, le paysage social des entreprises françaises a connu des mutations profondes. Animé par une ambition de déterminer l’organisation de travail la plus efficace, le « one best way », Taylor a poursuit son objectif en augmentant la productivité tout en rationalisant le travail (Zarifian, 2011). En retour, cette nouvelle organisation du travail a fortement contribué à la baisse significative du niveau d’activité physique quotidien et à une progression alarmante des comportements sédentaires. De plus, les progrès technologiques et l'avènement de l'ère numérique ont favorisé des conditions de travail de plus en plus exigeantes qui privent les individus d’une dépense physique essentielle au maintien d’une bonne santé physique et mentale. C'est dans ce contexte que les programmes d'activité physique au travail ont émergé, offrant une solution concrète pour contrer les méfaits de la sédentarité et de l’inactivité physique. Cependant, certains obstacles freinent cette dynamique. Cet article vise à réaliser une étude approfondie des enseignements sur les programmes d'activité physique au travail en adoptant une approche pluridisciplinaire.
Tetrazines et heptazines, les atouts des hétérocycles aromatiques à fort contenu d'azote
Authors: AUDEBERT Pierre
Published: March 2024

Les tétrazines sont des hétérocycles aromatiques stables contenant la plus forte proportion d’azote, relativement au carbone (composé générique C2H2N6). Ces composés, pourtant connus depuis un siècle, ont pourtant émergé seulement au XXIe siècle au niveau des applications les plus porteuses, la chimie click et la fluorescence ; nous présenterons quelques exemples et applications. Le cas des heptazines, un système tricyclique fusionné, même si un peu moins chargé en azote, (composé générique C6H3N7) constitue pourtant un cas assez analogue, mais encore plus marqué. En effet, la synthèse des heptazines étant plus délicate, ces molécules, pourtant très prometteuses, ont pendant longtemps été quasi-oubliées car presque non accessibles. De récents travaux ont conduit à l’obtention de deux nouveaux dérivés fonctionnalisables, ouvrant la voie à la synthèse de nouvelles familles de ces composés, et de nouvelles applications en particulier en photocatalyse, en optoélectronique ou dans le développement de matériaux hybrides.
Behavioral Variant Frontotemporal Dementia like Syndrome –Atypical Presentation of Intracranial Hypotension
Authors:   Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, USA, Khan Hiba , Rothenberg Kasia Gustaw ,   Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, USA
Published: March 2024

Spontaneous Intracranial Hypotension (SIH) is an uncommon syndrome which may result from a Cerebrospinal Fluid (CSF) leak. Atypical SIH may present with neurobehavioral symptoms similar to those observed in behavioral variant Frontotemporal Dementia (bvFTD). We present a case of a 55-year-old male with postural headache and behavioral symptoms who was initially diagnosed with bvFTD. On re-evaluation in our clinic, imaging revealed caudal displacement of the midline structures suggestive of Cerebrospinal Fluid (CSF) hypotension. We hypothesized that with unmitigated CSF loss over a long period of time, the patient developed brain sagging clinically resulting in neurobehavioral, frontal lobe dysfunction. After multitude of investigative procedures, a CSF venous fistula originating from a T7 nerve root cyst was found and repaired. Surgical intervention and restoration of CSF volume resulted in resolution of cognitive as well as neurobehavioral symptoms.
The Neuroprotective Effect of Clove Essential Oil Against 6-Ohda-Induced Cell Death in Sh-Sy5y and A Rat Model of Parkinson’s Disease
Authors:   INP, Institut Pascal, TGI, University of Clermont Auvergne, 63000 Clermont Ferrand France, Hamdi Dhouha , Ouachikh Omar ,   INP, Institut Pascal, TGI, University of Clermont Auvergne, 63000 Clermont Ferrand France, Ouchchane Lemlih ,   INP, Institut Pascal, TGI, University of Clermont Auvergne, 63000 Clermont Ferrand France, Omara-Reda Hend ,   INP, Institut Pascal, TGI, University of Clermont Auvergne, 63000 Clermont Ferrand France, Messaoud Chokri ,   Laboratory of Nanobiotechnology and Valorization of Medicinal Phytoresources University of Carthage National Institute of Applied Science and Technology UR17ES22 Tunis Cedex Tunisia, Hafidi Aziz ,   INP, Institut Pascal, TGI, University of Clermont Auvergne, 63000 Clermont Ferrand France
Published: March 2024

Parkinson’s Disease (PD) is the second most prevalent neurological disorder. Natural therapies are becoming more popular for preventing disease onset. Clove Essential Oil (CEO), a potent antioxidant derived from Syzygium aromaticum buds, was tested in vitro (SH-SY5Y) and in vivo (PD rat model) for its ability to protect against 6-OHDA-induced cell death. Twenty-four hours of SH-SY5Y cells’ exposure to 6-OHDA (100μM) drastically decreased cell viability. At doses lesser than 20μg/ml, CEO and its main component Eugenol (EG) had no cytotoxic effect on SH-SY5Y. CEO and EG at doses of 2.5-20μg/ml provided significant neuroprotection against 6-OHDA-induced cell death. A PD rat model was generated by injecting 6-OHDA (21μg/animal) unilaterally into the striatum. An assessment of motor performance can predict neuronal cell loss in the Substancia Nigra Compacta (SNc). Compared to 6-OHDA-lesioned, CEO-treated (10mg/Kg) rats’ locomotor performance (actimetry and cylinder tests) improved significantly one and two weeks after 6-OHDA-lesion. Tyrosine Hydroxylase (TH) cell count showed a significant decrease in cell death in ipsilateral SNc in both CEO-treated and 6-OHDA-lesioned rats when compared to contralateral. In contrast to the 6-OHDA-lesioned group, the ipsilateral SNc of the CEO-treated group showed a significant high TH cell number. In the present study, the neuroprotective effect of CEO was demonstrated both in vitro and in vivo against 6-OHDA cytotoxicity. Therefore, CEO could be used as a food supplement for PD prevention.
Understanding Blood Glucose for Healthcare Monitoring
Authors:   Department of Biomedical Engineering, School of Medicine, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu 42601, Korea, Thapa Mukesh
Published: March 2024

Glucose is the major glycolytic biomarker in blood. Measurement of blood glucose can assist in monitoring of various disease (like diabetes and, blood pressure) and understanding of individual health status (like obesity). Concentration of glucose in blood is easily affected by food intake and physical activities. So, measurement of only glucose can provide misinterpretation of health status. Phenomenon of protein glycation caused by glucose in bloodcan be a basis for understanding glucose condition in blood within longer period. Also, alternative biomarker of glycolysis like lactate can assist the results of blood glucose concentration. Understanding the concentration of glucose together with lactate and glycated proteins can provide complete glycolysis status in bloodso recently doctors are requesting measurement these biomarkers along with glucose for high-risk disease management. This short communication dwells upon the importance of glucose in blood for health care management.
Purification and Characterization of Glucosamine Oxidase from Aspergillus Terreus NUK-1204 for Production of Glucosaminic Acid
Authors:   Department of Life Sciences, National University of Kaohsiung, 700, Kaohsiung University Road, Taiwan, Lin Shuen-Fuh , Huang Pang-Hung ,   Department of Life Sciences, National University of Kaohsiung, 700, Kaohsiung University Road, Taiwan
Published: March 2024

D-Glucosaminic acid (2-amino-2-deoxy-D-gluconic acid) is a valuable glucosamine derivative from the oxidation of the glucosamine (2-amino-2-deoxy-D-glucose). It can be produced via the fermentation of certain microorganisms, which involves complicated purification task, though. In an attempt to find an enzyme suited to glucosaminic acid production, the study presented a purified homogeneous glucosamine oxidase deriving from the wheat bran culture of a soil-isolated fungal strain, Aspergillus terreus NUK-1204. Maximum activity was observed in the wheat bran solid culture after five days of NUK-1204 growth, following its release from cells at 0.011 unitmL -1culture filtrate. The new kind of oxidase comprises a single polypeptide chain with a molecular mass of 54 kDa, containing FAD and exhibiting absorption maxima at 274, 372 and 439 nm. The enzyme was stable in 4.5-11 pH range, with an optimal reaction pH at 10.5 and optimal reaction temperature at 30°C. It remained stable at 20-50°C for 1 hr. The relative activity of glucosamine oxidase towards glucosamine and N-acetyl-glucosamine was 100:7, demonstrating high substrate specificity. It doesn’t inhibit glucosamine. To the best of our knowledge, this is the first report ever on the discovery of a glucosamine oxidase based on enzyme substrate specificity.
Molecular Characterization of SHV, BLA-OXA and B-Lactamase Resistant Genes Leading to Computational Based Inhibitor Screening Against Bacillus Species
Authors:   Department of Biotechnology, University of Central Punjab, Lahore, Pakistan, Khan Nida , Munaf Eisha ,   Department of Biotechnology, Jinnah University for Women, Karachi, Pakistan, Asif Muneer Muhammad ,   Centre for Applied Molecular Biology, University of the Punjab Lahore, Pakistan, Ashraf Muhammad Hamza ,   Centre for Applied Molecular Biology, University of the Punjab Lahore, Pakistan, Mumtaz Ayesha ,   Centre for Applied Molecular Biology, University of the Punjab Lahore, Pakistan, Zeeshan Muhammad ,   Insitute of Microbiology and Molecular Genetics, University of the Punjab Lahore, Pakistan, Khan Kamran ,   Shaheed Benazir Bhutto University Dir Upper, Pakistan, Rizwan Ali Muhammad ,   Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan
Published: March 2024

Antibiotic resistance in bacterial pathogen is a great challenge that is connected with excessive morbidity and mortality of living beings. A common motive of antibiotic resistance in bacteria is an increased abundance of Β- lactamases. There chromosomal Β- lactamases do not generally provide effective antibiotic resistance in wild type Bacilli despite evidence that the genes are not completely silenced. Under antibiotic selection pressure however, a number of strains show increased resistance suggesting mutation induced up regulation of Β- lactamases. Computer-assisted drug design has made significant progress in predicting biologically active molecules and their receptor binding conformation, with results that are sometimes more exact than those acquired through traditional methods like as high-throughput screening. The results of computational studies are sometimes more precise than the experimental possibilities, and they contribute to the improvement of the experimental array. In this study, identified pathogenic species of bacillus, and analyzed the antibiotic resistant genes. The Previous study of its characterization showed the presence of BLA-OXA and SHV genes in Bacillus cereus and Bacillus paramycoides. The sequenced antibiotics resistant genes were subjected to computational analysis for the interpretation of the potential inhibitors against BLA-OXA and SHV. The analyzed inhibitor will enable to study the diversity of antibiotic resistant mechanism and to minimize the resistance of bacterial species against antibiotics.
Electronically Tunable Non-Fullerene Acceptor Based Ka-Band Phase Shifter
Authors: Manikandan suraj , Andreasen Jens
Published: March 2024

This communication introduces a Ka-band phase shifter that leverages a blend of the donor polymer PM6 and non-fullerene acceptor (NFA) Y7 organic materials. The design integrates a coplanar waveguide (CPW) with a spin-coated thin film of PM6:Y7 blend, characterized by its dielectric nonlinearity and light sensitivity. An applied electric field between the CPW signal and ground electrodes governs the phase shift mechanism, effectively modulating the permittivity of the blend. Our study reveals a significant differential phase shift of up to 28 degree at 38 GHz across the waveguide's 1000 um. Additionally, we explore the dynamic interplay between illumination and temperature on the performance of the phase shifter, providing insights into its operational versatility. The findings underscore the substantial potential of NFA-based phase shifters in millimeter-wave applications and adaptive communication systems, such as active antennas, marking a significant stride in developing organic material-based electronic components for self powered next-generation technologies.
Percolation-induced ferrimagnetism from vacancy order in [Gua]Mn1–xFe2x/3(HCOO)3 hybrid perovskites
Authors: Bulled Johnathan , Willis Alexandra , Faure Beaulieu Zoe , Cassidy Simon , Bruckmoser Jonas , Boström Hanna , Goodwin Andrew
Published: March 2024

We report the magnetic behaviour of the hybrid perovskites [Gua]Mn1–xFe2x/3(HCOO)3 (0 < x < 0.88), showing that vacancy ordering drives bulk ferrimagnetism for x > 0.6. The behaviour is rationalised in terms of a simple microscopic model of percolation-induced ferrimagnetism. Monte Carlo simulations driven by this model reproduce the experimental dependence of magnetic susceptibility on x and show that, at intermediate compositions, domains of short-range vacancy order lead to the emergence of local magnetisation. Our results open up a new avenue for the design of multiferroic hybrid perovskites.
Monomer-Recyclable Polyesters From CO2 and 1,3-Butadiene
Authors: Xu Jialin , Niu Yuxuan , Lin Bo-Lin
Published: March 2024

NOTE：This paper was submitted to Journal of the American Chemical Society at 31-Jan-2024, Manu-script ID: ja-2024-01537k. Recently, we found a very similar work published on ChemRxiv DOI: 10.26434/chemrxiv-2024-0p22l, therefore we decide to publish our work on ChemRxiv also. Synthesis of monomer-recyclable polyesters solely from CO2 and bulk olefins holds great potentials in significantly reducing CO2 emissions and addressing the issue of plastic pollutions. Due to the kinetic disadvantage of direct copolymerization of CO2 and bulk olefins compared to homopolymerization of bulk olefins, considerable research attention has been devoted to synthesis of polyester via the ring-opening polymerization (ROP) of a six-membered disubstituted lactone intermediate, 1,2-ethylidene-6-vinyl-tetrahydro-2H-pyran-2-one (𝜹-L), obtained from telomerization of CO2 and 1,3-butadiene. However, the conjugate olefin on the six-membered ring of 𝜹-L leads to serious Michael addition side reactions. Thus, selective ROP of 𝜹-L, which can precisely control the repeating unit for the production of polyesters potentially amenable to efficient monomer recycling, remains an unre-solved challenge. Herein, we report the first example of selective ROP of 𝜹-L using a combination of organobase and N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]urea as the catalytic system. Systematic modifications of the substituent of the urea shows that the presence of electron-deficient 3,5-bis(trifluoromethyl)-phenyl groups is the key to the extraordinary selectivity of ring opening over Michael addition. Efficient monomer recovery of poly(𝜹-L) was also achieved under mild catalytic conditions. This work proves that it is possible to synthesize monomer-recyclable polyester by only using CO2 and bulk olefin as the feedstock, provid-ing a new strategy to potentially fix CO2 in polymeric materials at large scales.
Scabies in dermatovenerologist practice: a clinical case of delayed diagnosis in a patient with chronic dermatosis. Case report
Authors: Ufimceva Marina A. , Bochkarev Yurii M. , Nikolaeva Kristina I. , Gurkovskaya Evgenia P. , Мylnikova Ekaterina S. , Podkorytova Oksana M.
Published: March 2024

Despite the current approaches to diagnostics and treatment, regulatory documentation and guidelines, the diagnosis of scabies can often be delayed. The long-term scabies can mimic acute and chronic dermatoses which causes inadequate treatment. Physicians, including dermatovenerologists, misdiagnose scabies. Aim – to clarify historical aspects of scabies, present a clinical case of scabies complicated by allergic dermatitis and lymphoplasia in a patient with Darye's disease as an example of delayed diagnosis of scabies, errors in management tactics and features of treatment of scabies in a patient with chronic dermatosis.
Comorbid functional pathology in gastroenterology. Possibilities and prospects for drug treatment: A review
Authors: Osadchuk Alexey M. , Loranskaya Irina D. , Osadchuk Mikhail A.
Published: March 2024

Functional disorders of the gastrointestinal tract (FD GT) and their intersection are relevant due to their high prevalence in the population, decrease and, in some cases, loss of performance, low quality of life and treatment difficulties. Despite the large number of consensuses and clinical recommendations at the national and international level, the effectiveness of therapy for FD GT and their overlap does not exceed 30-50%. There is a high degree of comorbidity of these diseases, called “overlap syndromes,” due to common pathogenetic mechanisms. This predetermines the need to use drugs with a multi-target therapeutic effect in the treatment of such pathology. Such drugs include trimebutine (Trimedate®), probiotics and psychotropic drugs. Data obtained in recent years on the presence of anti-inflammatory, antimicrobial, regenerative effects in relation to nervous and epithelial tissue and anti-carcinogenic effects in trimebutine make it unique for the treatment of gastrointestinal diseases and their intersection. Currently, there is a search for new promising drugs for the treatment of both individual FD GT and their overlap, as well as improving the regimens of existing treatment methods. The review article is devoted to existing opportunities and new horizons for the treatment of FD GT and their overlap.
Psycho-emotional state during pregnancy and one year after childbirth in mothers of children with functional gastrointestinal disorders
Authors: Griaznova Ekaterina I. , Dubrovskaya Maria I. , Turchinskaya Anastasia I. , Botkina Alexandra S. , Kovtun Tatiana A.
Published: March 2024

Aim. To determine the relationship between the incidence of functional gastrointestinal disorders in children up to 1 year of age and the psycho-emotional state of their mothers during pregnancy and after childbirth.
Materials and methods. A survey of 1203 mothers of children under 4 years of age was conducted using a questionnaire of functional gastrointestinal disorders according to the Rome IV criteria (2016). The questionnaire contained domains on general issues (the age of the mother at the time of the child's birth, the data of obstetric and gynecological anamnesis, the type of child's nutrition at the time of the survey), psycho-emotional state (retrospectively, the psychological component of the gestational dominant – PСGD – during pregnancy, Beck's anxiety and Beck's depression questionnaires) and questions on functional disorders in infants and young children.
Results. Questionnaires of 487 mothers of children of the 1st year of life were analyzed. Only in 34.4% of cases, mothers' responses lacked anxious and depressive PCGD. In mothers with anxious PСGD, the risk of regurgitation in their children was statistically significantly 2-fold higher compared to mothers with depressive PСGD. In mothers with optimal PСGD, the rate of colic in their children was statistically significantly 2-fold lower compared to mothers with anxious and depressive PСGD. After childbirth, anxiety was noted in 17% mothers and signs of depression in 59% mothers. Significant and severe depression was diagnosed in 10% mothers; the children of these mothers had persistent regurgitation.. In the absence of depression in mothers, the probability of no regurgitation and colic in their children was statistically significantly 2-fold higher compared to the children of mothers with depression.
Conclusion. The incidence of functional gastrointestinal disorders in a child up to 1 year of age is associated with maternal anxiety during pregnancy and maternal depression after childbirth.
Clinical and economic analysis of the application of the method of three-dimensional reconstruction of lung tissue in the practice of tuberculosis institution
Authors: Naumov Alexey G. , Shprykov Alexander S. , Borodina Natalya Yu.
Published: March 2024

Background. The use of clinical and economic analysis in practical healthcare allows for a more rational use of the resources allocated by the state and contributes to the achievement of optimal indicators in terms of the quality of disease identification and the effectiveness of its treatment.
Aim. To conduct a clinical and economic analysis of the prospects for introducing the 3D lung reconstruction method into tuberculosis practice, which is used to correct the level of adherence, reduce the severity of symptoms of anxiety and depression, and increase the effectiveness of chemotherapy.
Materials and methods. In this scientific work, the results of treatment (more than 90 people) of newly diagnosed patients with destructive pulmonary tuberculosis, which were observed in the Nizhny Novgorod Regional Clinical Tuberculosis Dispensary, were used. The patients were divided into two groups. For the 1st group of patients, tactile lung models were made, among them a questionnaire was conducted using the MMAS-4 questionnaire and the HADS scale. For patients of the 2nd group, lung models were not made, and no survey was conducted. Each group was assessed the effectiveness of chemotherapy. Clinical and economic analysis of the cost of introducing the method of three-dimensional lung reconstruction into tuberculosis practice was carried out on the basis of two evaluation criteria «cost – effectiveness» and «cost-effectiveness increment» with additional mathematical calculations of the necessary indicators. The results obtained were compared with the existing known method of increasing adherence to tuberculosis treatment - the issuance of food packages.
Results. Based on the results of the study, it was proved that the use of tactile models of the lungs in phthisiatric practice is more than 8 times cheaper than the method of issuing food kits with, in fact, comparable results of treatment effectiveness. If there is a need to increase the effectiveness of the treatment of tuberculosis patients by increasing the subsidy of food packages, the cost of one additional percent of efficiency is not economically viable.
Conclusion. The clinical and economic analysis of the prospects for introducing the method of three-dimensional lung reconstruction into phthisiatric practice presented in the paper looks promising, which is confirmed by the performed mathematical calculations and comparisons, and can be recommended for use in the routine practice of phthisiatricians to correct the level of adherence of tuberculosis patients to chemotherapy, reduce the severity symptoms of anxiety and depression, as well as an increase in the effectiveness of treatment.
Performance Testing of KNN and Logistic Regression Algorithms in Classifying Heart Disease Susceptibility
Authors: Saputro Pujo Hari , Zalmi Wahyuni Fithratul , Syahputra Rendy
Published: March 2024

The annual global death toll due to cardiovascular diseases, which fall into the category of heart and blood vessel disorders, reaches 17.9 million lives. This undoubtedly requires more attention in order to anticipate the potential risk of heart attacks that can affect anyone at any time. Data analysis or data mining approaches have become a significant contribution in the field of information technology to provide valuable information regarding the risk of heart diseases. Data analysis using the K-Nearest Neighbor and Logistic Regression algorithms is expected to provide information related to the susceptibility category for heart diseases, such as age susceptibility, gender, cholesterol levels, and so on. With the information obtained from this data analysis, it is hoped that it can serve as a reference and consideration for individuals to be more vigilant in maintaining their health. The results indicate that the highest correlation with susceptibility to heart disease is based on a person's age and their body weight. The correlation coefficient between these two variables is 0.37, suggesting a relationship between a person's age and their body weight, which can make them more susceptible to heart disease. Testing with both algorithms shows a high level of accuracy, with K-Nearest Neighbor achieving an accuracy rate of 0.95, while Logistic Regression has an accuracy of 0.96.
Investigation on the Effectiveness of Botanicals and New Generation Insecticides in the Management of the Pink Bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae), in the Cotton Ecosystem
Authors:   1Department of Crop Protection, TRIARD, Perambalur,Tamil Nadu, India. Corresponding author:, Shree Padma , M Muthuswami ,   Office of the Registrar, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India., K Senguttuvan ,   KVK, Vridhachalam, Tamil Nadu, India., S Rajeswari ,   4Department of Cotton, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India., N Manikanda Boopathi ,   Department of Plant Biotechnology, Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India.
Published: March 2024

The pink bollworm, Pectinophora gossypiella (Saunders), is a worldwide important emerging insect pest that is causing major yield loss among the bollworms in the cotton ecosystem. A field study evaluated the bio-efficacy of newer insecticides and botanicals against pink bollworm during Kharif and Rabi, 2021-22, under Randomised Block Design (RBD). The observations on percent boll damage, percent locule damage, percent reduction over control, and yield were recorded and analyzed. The results showed that applying emamectin benzoate 5SG was superior to other treatments, followed by chlorantraniliprole 18.5 SC, spinosad 45 SC and flunbendiamide 39.5 SC. The emamectin benzoate 5 SG treated plot had the greatest reduction in boll damage (89.25%) and the highest yield (1955 kg/ ha). Among the botanicals, 5 % NSKE was found to be effective with a damage reduction over control of 58.06 % followed by 5 % neem formulation 1500 ppm (50.54 %) against pink bollworm in cotton.
ANÁLISE DOS ÍNDICES DE REALIZAÇÃO DO PRÉ-NATAL E SUAS IMPLICAÇÕES MATERNO-FETAIS, EM UMA UNIDADE BÁSICA DE SAÚDE DO MUNICÍPIO DE CUIABÁ-MT
Authors: Rossi Renata Carolina Woolley de Carvalho Martins , Barbosa Pedro Eduardo Barros , Colla Sandy Danielle Camila Figueiredo
Published: March 2024

Foram realizadas análises de perfis de 12 gestantes, em uma Unidade Básica de Saúde em Cuiabá-MT, com
faixa etária entre 18 e 36 anos, a fim de classificá-las acerca da realização do pré-natal. Além disso, visando elucidar
a importância e os benefícios intrínsecos com a realização do pré-natal, foi desenvolvida uma ação no Parque Mãe
Bonifácia. Como resultado, foi possível, aumentar a adesão ao pré-natal, a realização de exames, tratamento e
investigações sobre malformações no feto de forma precoce, resultando em um melhor desfecho clínico. Logo, por
meio do desenvolvimento desse trabalho, foi possível melhorar a qualidade de vida das gestantes participantes, haja
vista, que a realização do pré-natal é um procedimento essencial para a boa desenvoltura gestacional.
NEOPLASIA MAMÁRIA MALIGNA NA REGIÃO SUDESTE BRASILEIRA ENTRE 2020 A 2023: ESTUDO ANALÍTICO E EPIDEMIOLÓGICO
Authors: Petri Samyra Bertoli , Robert Isabela Silva , Peçanha Luísa Matiello , Macedo Maria Eduarda Zanette
Published: March 2024

No cenário global, em 2021, o tumor de mama se tornou a neoplasia mais comumente diagnosticada no
mundo. Já no Brasil, no ano de 2023, essa neoplasia atingiu 30,1% da população feminina. Mesmo, comumente, não
apresentando sintomas na fase inicial, é o tipo de câncer que mais mata mulheres no mundo e está relacionado a
alterações genéticas em algum conjunto de células da mama, que passam a se dividir descontroladamente. Objetivo:
Este estudo tem como objetivo caracterizar o perfil epidemiológico da população brasileira na Região Sudeste em
relação à prevalência de casos de Neoplasia maligna da mama entre os anos de 2020 a 2023. Método ou Metodologia:
Estudo ecológico, retrospectivo, quantitativo e descritivo, cujo os dados foram obtidos a partir de consultas realizadas
no Sistema de Informação Hospitalares (SlH/SUS), através da plataforma do Departamento de Informática do Sistema
Único de Saúde (DATASUS), referentes ao período de 2020 a 2023. Analisou-se a Região Sudeste e seus respectivos
Estados, além da faixa etária e sexo mais acometido pela doença. Resultados: Com base na análise, foram constatados
285.282 casos confirmados de neoplasia maligna de mama no Brasil entre os anos de 2020 a 2023, sendo que destes
71.568 (25,08 % do total) foram do ano de 2023. Nesse sentido, o maior predomínio foi na Região Sudeste
apresentando 139.256 (48,8 % do total), com destaque no estado de São Paulo que possui 51,9 % dos casos da região.
Em relação à faixa etária na Região Sudeste, esta condição está presente em todas as idades, evidenciando um total de
38.157 (13,3 % do total) no intervalo de 50 a 59 anos, porém é mais prevalente em mulheres do mesmo período, que
manifestam 37.957 casos do total entre 50 a 59 anos (99,4%). Ainda, é notório que a partir dos 49 anos há um aumento
dos casos em todos os estados da região. Conclusão ou Considerações Finais: O câncer de mama afeta todas as
idades, com maior incidência após os 50 anos e no sexo feminino. Fatores de risco incluem idade, fatores
endócrinos/história reprodutiva, fatores comportamentais/ambientais e fatores genéticos/hereditários. A maior
prevalência em mulheres está relacionada principalmente à composição biológica e hormonal do corpo feminino, já
que este é influenciado por fatores hormonais. Além disso, as mamas nas mulheres passam por mudanças durante a
puberdade, podendo aumentar o risco de desenvolver câncer de mama.
Passando a Boiada: Representações do Discurso Ecológico Sobre o Brasil na Imprensa dos Estados Unidos no Governo de Jair Bolsonaro
Authors: Santos Adelino Pereira dos , Araújo Aleffe Silva
Published: March 2024

Tomando como pressupostos teóricos e metodológicos a Análise do Discurso Crítica, neste artigo analisamos manchetes de agências de notícias, jornais e revistas de repercussão internacional, publicadas nos Estados Unidos, que abordam o discurso ecológico do/sobre o Brasil durante a gestão do governo Jair Bolsonaro (2019 a 2022) à presidência da república. A análise teve como objetivo identificar elementos lexicais, construções sintáticas, figuras de linguagem e aspectos semânticos que se constituíssem em representações discursivas sobre o Brasil e, consequentemente, revelassem práticas discursivas e sociais dos atores sociais que se inscrevem nas manchetes. Como resultados, pudemos concluir que as representações sobre o Brasil no que se referem às políticas ecológicas e/ou ambientais do governo Bolsonaro foram majoritariamente negativas, o que representavam as práticas sociodiscursivas do governo em geral e do próprio presidente da república em particular.
Letramento e (In)funcionalidade: (Des)Interesse e a Necessidade do Produzir no Sistema Escolar
Authors: Goulart Anderson Jair , Schneider Leonardo , Hasse Leonardo
Published: March 2024

O presente ensaio reúne uma série de reflexões acerca de nossa experiência inicial em sala de aula, reverberando argumentos entornados pelas referências teóricas com as quais tivemos contato durante a licenciatura, resgatando-as memorialística e pessoalizadamente, sobretudo as discussões sobre identidade e infuncionalidade discutidas por Ponzio (2010) e Cerutti-Rizzatti e Irigoite (2015). Desse modo, encontram-se aqui uma série de fruições advindas das impressões apreendidas no estágio de docência, clareadas à intenção de complementar às problemáticas do ensino e aprendizagem baseando-se em nossa recém-nascida bagagem docente e, simultaneamente, deslocando o enfoque às mudanças de hábito atestadas no contato com os alunos, às ligeiras inovações tecnológicas e seus impactos sobre o cotidiano escolar. Premidos por essas percepções, é nosso intuito responder à seguinte questão: Como agir em situações protagonizadas pelo desinteresse e quais as possíveis causas que levam a essa postura em ação docente que busca a integração discente em prática de uso da linguagem? Assim, muito do conteúdo abarcado ao longo de nossas reflexões destaca hábitos corriqueiros, porém prejudiciais ao ensino e à aprendizagem, ecoando vontades teóricas fundamentadas à luz de uma predisposição à formação crítica por meio do infuncional, investigando possíveis causas às dificuldades vivenciadas, designados ao cargo de ser professores.
Tecnologia Digital no Ensino de Língua Inglesa em Contexto Municipal
Authors: Cunha José Ricardo de Oliveira
Published: March 2024

Este artigo discorre acerca da introdução de tecnologias da informação e da comunicação (TICs) no contexto de ensino presencial de Língua Inglesa (LI), com foco em um estudo de caso concreto de inserção de tecnologias digitais no ensino de LI no contexto da educação pública de uma rede municipal de ensino, em uma cidade localizada no interior do estado de São Paulo. A partir da análise do processo de reestruturação curricular da LI ocorrida no Ensino Fundamental e iniciada em 2022, a concomitante inserção das tecnologias digitais objetivou potencializar as oportunidades de aprendizagem dessa língua pelos estudantes dessa rede, em específico no âmbito do segmento Anos Iniciais, ou seja, do 1º ano ao 5º ano. O ensino e a aprendizagem de línguas estrangeiras modernas ou adicionais são tidos como um ambiente bastante propício para a introdução de inovações tecnológicas, no qual sua relevância se faz notar (Paiva, 2019). A utilização de TICs intensificou-se nos últimos anos, sobretudo no ambiente escolar, por meio de ferramentas digitais e de instrumentos tecnológicos capazes de proporcionar experiências de ensino e aprendizagem outrora inimagináveis nesse contexto (Kairallah, 2018).
La Necesaria Reivindicación de Paulo Freire en Tiempos de Aceleración Disruptiva y Recualificación del Quehacer Educativo
Authors: Arévalos José Manuel Silvero , Coronel Derlis Ortiz , Maciel Mariza Amaral
Published: March 2024

En este artículo se pretende explorar un concepto troncal en la lógica disruptiva, el de la aceleración. Entendiendo desde una perspectiva multidisciplinar y analizando sus implicaciones y consecuencias, especialmente en la educación. Se parte de la idea de que la aceleración es un fenómeno complejo y ambivalente, que puede tener efectos positivos o negativos según cómo se gestione y se experimente. Se revisan de manera sucinta algunos aportes de la literatura, de la filosofía y de pedagogos y en base a ellos se reflexiona en torno a los grandes desafíos y las enormes oportunidades que supone vivir en una sociedad acelerada teniendo como base los aportes de Paulo Freire. El objetivo es contribuir al debate sobre el papel de las tecnologías disruptivas y la necesaria recualificación de algunos aspectos centrales del quehacer educativo, basados en modelos pedagógicos pertinentes para este contexto del tiempo presente.
A EVOLUÇÃO DA LEGISLAÇÃO BRASILEIRA COMO FORMA DE FOMENTO DA ESCALABILIDADE DAS OPERAÇÕES DA AVIAÇÃO NÃO TRIPULADA NO BRASIL
Authors:   , REGIS JORGE
Published: March 2024

O crescimento da aviação não tripulada tem trazido grandes desafios às autoridades reguladoras ao redor do mundo, com vistas à integração dessa nova entrada em um ambiente até pouco tempo, de uso exclusivo da aviação tradicional. Embora a utilização dessa nova tecnologia prometa benefícios significativos para a sociedade, a ausência do piloto a bordo levanta questões complexas, cujas respostas estão intimamente relacionadas ao desenvolvimento tecnológico. Nesse sentido, as autoridades reguladoras brasileiras têm acompanhado o amadurecimento do setor e engendrado esforços para manter, por meio da adoção de um conceito conhecido como "documentação viva", a regulamentação brasileira constantemente atualizada, servindo como um facilitador para o fomento seguro dessa indústria. Portanto, a pesquisa consistiu em se verificar a relação entre a evolução da regulamentação brasileira e a escalabilidade das operações de aeronaves não tripuladas, no Sistema de Controle Espaço Aéreo Brasileiro. Para tanto, realizou-se uma pesquisa documental, consistindo em um levantamento das legislações brasileiras e intentes ao setor não tripulado, bem como uma análise dos dados constantes no Sistema de Solicitação de Acesso de Aeronaves Remotamente Pilotadas (SARPAS). A pesquisa demonstrou que, após a última atualização da ICA 100-40, realizada em julho de 2023, houve um aumento significativo nas autorizações automáticas para acesso ao espaço aéreo brasileiro, passando de 77,99% para 92,46%. Paralelamente, as análises manuais diminuíram significativamente de 22,01% para 7,54%. Esse estudo revelou um aumento de 111,94% nas autorizações automáticas e reduções de 39,93% e 22,21% nas análises manuais para operações sem e com necessidade de NOTAM, respectivamente.
MENELISIK FENOMENA PERCERAIAN PADA AKTOR PERNIKAHAN DINI DALAM PERSPEKTIF STRUKTURAL FUNGSIONAL
Authors: Abdullah Mirna Nur Alia
Published: March 2024

Early marriage is generally carried out by young couples who are not mentally and physically ready to build a quality household. The purpose of this study is to examine and explain the phenomenon of divorce in early marriage cases based on functional structural theory. The method used in this research is a literature study, which is the process of selecting, reading, recording and collecting references that are relevant to the topic of study as a data source. The results of the study state that until now, divorce has become one of the crucial problems considering the negative impact caused after divorce is very complex, especially in cases of divorce that occur in actors who previously underwent young marriages. Functional structural theory views that divorce occurs because of an imbalance in the family. In addition, early marriage has a higher potential for divorce due to the lack of individual readiness, so that instability in the family occurs more often, in this case early marriage is prone to divorce. Therefore, to realize a harmonious marriage based on a functional structural perspective, it is necessary to balance the system to achieve this goal.
DAMPAK PERNIKAHAN DINI TERHADAP POTENSI BABY BLUES SYNDROM PADA IBU MUDA DI KABUPATEN BANDUNG
Authors: Khairunnisa Firda Salsabila , Abdullah Mirna Nur Alia
Published: March 2024

Pernikahan usia dini merupakan pernikahan yang terjadi pada seorang anak di bawah umur 19 tahun. Di Indonesia fenomena pernikahan dini bukan hal yang baru, bahkan pernikahan dini sering kali disebut sebagai sebuah tradisi oleh masyarakat. Dari data BPS pada tahun 2022 sebanyak 19,24% anak muda di Indonesia yang berusia 16-18 mencatatkan pernikahnnya. Kurangnya pengetahuan mengenai resiko dari pernikahan dini mengakibatkan tingkat pernikahan dini di Indonesia tinggi. Sebagian masyarakat tidak mengetahui tentang resiko yang terjadi saat melakukan pernikahan dini terutama yang akan di alami oleh perempuan. Salah satu resiko pernikahan dini yang dialami oleh perempuan adalah depresi atau stress yang dapat berpotensi mengalami baby blues syndrom saat memiliki anak.  Sehingga, penelitian ini bertujuan untuk mengetahui hubungan antara menikah dini terhadap potensi baby blues syndrom yang terjadi pada perempuan pasca melahirkan. Metode penelitian ini menggunakan jenis penelitian deskriptif dengan pendekatan kualitatif.  Partisipan yang terlibat dalam penelitian ini berjumlah 3 orang yang dipilih secara purposive sampling dengan kriteria perempuan yang menikah di bawah 19 tahun dan pernah mengalami baby blues syndrom. Teknik pengumpulan data menggunakan teknik wawancara yang kemudian hasilnya dianalisi melalui deskriptif kualitatif.  Hasil dari penelitian ini menunjukkan bahwa ibu yang menikah pada usia muda memiliki potensi yang lebih tinggi untuk mengalami Baby blues syndrome. Beberapa faktor utama yang mempengaruhi hubungan antara pernikahan dini dan Baby blues syndrome adalah kurangnya kesiapan menjadi seorang ibu atau kurang kesiapan dari segi psikis. Ada pun faktor pendukung lainnya seperti finansial dan dukungan sosial yang kurang.
EKSISTENSI SARABBA SEBAGAI MINUMAN TRADISIONAL KHAS BUGIS-MAKASSAR DI ERA MODERN
Authors: Masyudi Ayudia Rostiara , Nabila Fadia Marsya , Abdullah Mirna Nur Alia
Published: March 2024

Sarabba is a traditional drink made from ginger and brown sugar originating from South Sulawesi, especially the Bugis and Madurese tribes. The purpose of this article is to find out the potential of sarabba to become a trend like coffee among young people and what innovations have been made as an effort to maintain the existence of sarabba in this modern era. The research method used is a qualitative method using an ethnographic approach and with data collection techniques through literature studies and also interviews to related parties whose results will be in the form of words. From the results of the research, sarabba has undergone many developments starting from packaging that is starting to be attractive and varied flavors such as mocca and chocolate flavors, and currently there are many instant or powder sarabba and also the ice cream version of sarabba, so the possibility of sarabba becoming a trend like coffee among teenagers is getting bigger, considering that in Makassar itself sarabba is much loved and is everywhere. So it can be concluded that: 1) There have been many innovations to maintain the existence of sarabba in this modern era, for example the sarabba innovation carried out by Sarabba Sukma Jahe Makassar and Sarabba Indonesia stores. This innovation is done by changing the shape and creating new flavor variants. Innovation in terms of form, namely there is sarabba in instant form and sarabba in the form of ice cream. While from the flavor variants there are mocca, chocolate and milk flavors. 2) Sarabba has the potential to become a trend among young people but is still within a limited scope, namely in Makassar. With the many innovations in sarabba today, it is certainly a driving factor for sarabba to become a trend among young people. However, when compared to the coffee trend, the sarabba trend is quite difficult to realize.
PENGARUH STRATEGI PEMBELAJARAN DAN KEMAMPUAN BERPIKIR KRITIS TERHADAP HASIL BELAJAR SOSIOLOGI MAHASISWA
Authors: Muzakar Abdullah , Tohri Ahmad , Asror M Zainul
Published: March 2024

Appropriate learning strategies and critical thinking skills affect student learning outcomes. This study aims to examine the effect of learning strategies on group investigation and direct instruction with the ability to think critically on student learning outcomes in the subject of Industrial Sociology. This research was conducted with true-experimental techniques in 2 classes of students. The total sample of this study were 45 students. This research data collection uses two methods: tests and questionnaires. Data analysis using descriptive and inferential two-way ANAVA 2 x 2 techniques. The results showed that the results of the Dunnet t test for different mean learning strategies was significant (sig. = .000 ˂ ɑ = .05), the critical thinking skills level was significant (sig. = .000 ˂ ɑ = .05), and learning outcomes was significant (sig. = .000 ˂ ɑ = .05). In classes that are treated and the ability to think critically high, high learning outcomes. Thus it was concluded that the learning strategy of group investigation and the level of critical thinking ability was very influential in improving the students learning outcomes of the Sociology Education Study Program at Hamzanwadi University Semester IV Academic Year 2018/2019, in the Industrial Sociology subject.
PENGARUH METODE PEMBELAJARAN SOSIODRAMA DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR SEJARAH
Authors: Badarudin Badarudin , Tohri Ahmad , Asror M Zainul
Published: March 2024

This research aims to determine the differences in learning outcomes of students in the History Education Study Program at Hamzanwadi University who are taught through the sociodrama method and the lecture method. This research uses a quasi-experimental method. The research design used a 2x2 by level treatment design. The sampling technique uses multistage random sampling. The total sample was 44 students who were divided into 22 experimental groups and 22 control groups. Data collection uses two methods, namely tests and questionnaires. Data analysis used descriptive and inferential techniques, two-way ANOVA. The results of analysis of research data with a significance level of α 0.05 showed that Fcount (Fh = 7.77) was greater than Ftable (Ft α 0.05 = 4.08). This is in accordance with the average value of history learning outcomes for the group of students taught using the sociodrama method ȲA1 = 26.68 and the group of students taught using the lecture method ȲA2 = 23.23;. The results of this data analysis show that the history learning outcomes of the student group taught using the sociodrama method were higher than the learning outcomes of the student group taught using the lecture method
OBJEKTIFIKASI TUBUH LAKI-LAKI DALAM EKSPRESI SEKSUAL PEREMPUAN DI MEDIA SOSIAL
Authors: Astari Ayang
Published: March 2024

This research aims, among others: (1) How is the form of expression of women in objectifying the male body on social media, (2) Knowing the responses and opinions of some users who see the objectification of the male body on social media. The method used in this research is descriptive qualitative method, with a phenomenological approach. With data collection through non-participant observation in Twitter social media. Based on the results of the study, it can be concluded that women basically also have the same sexual desires but have their own ways of conveying their sexual expressions. The results in this study show: (1) Through social media they give forms of expression with sensual language such as, the desire to be raped, to declare their uterus warm just by looking at a man's body image. (2) Differences in perception between the pros and cons of the reality that occurs in social media, but the perception of other social media users chooses to be against the actions taken by women in social media.
DJARUM FOUNDATION BAKTI BUDAYA DALAM MENINGKATKAN KAPASITAS ALFA SHOOFA BATIK KUDUS
Authors: Fadhilah Nurul , Khoiriyah Nur
Published: March 2024

PT Djarum which is called the Djarum Foundation. This researcher discusses the Djarum Bakti Budaya Foundation in improving the efforts of Alfa Shoofa Batik Kudus. Alfa Shoofa Batik Kudus is one of the batik businesses in Kudus. The discussion in this study discusses the strategy and implementation of the Djarum Foundation in enhancing the efforts of Alfa Shoofa Batik Kudus. This research uses descriptive qualitative research in the form of field research, while data collection techniques such as observation, interviews, and documents. The results showed that the Djarum Bakti Budaya Foundation was a form of concern for the cultural results of the Indonesian people. Meanwhile, Alfa Shoofa Batik Kudus is a home for the production of traditional handmade batik, hats and embroidery that is lifted and preserves the culture of Kudus. In enhancing Batik Alfa Shoofa's business, the Djarum Foundation has a strategy of (1) approving, (2) developing human resources, (3) developing promotion. The assessment stage, the assessment stage, installation of treatment, maintenance of actions, monitoring and evaluation, termination and action. Development is carried out using Direct Contacts which is carried out with business training in the form of tourism.