bluuebunny/crossref_metadata_2025 huggingface dataset:
Biochemical, physiological, and molecular responses of diverse olive cultivars to different irrigation regimes
Authors: ALOWAIESH Bassam F. , EL-MANSY Ahmed B. , EL-ALAKMY Dina A. , REHEMA Esraa A. , ABD EL-MONEIM Diaa
Published: December 2023

Olive is an essential industrial crop in the Mediterranean region with valuable economic and agricultural concerns. Despite its drought resistance, its productivity is restricted by extreme drought stress. Olive cultivars display considerable variation in response mechanisms to drought stress. Accordingly, the impact of mild and extreme water deprivation over two seasons compared to full irrigation requirements on growth and physiological characteristics of three diverse olive cultivars. Three olive cultivars, ‘Manzanillo’, ‘Eggizi-Shami’, and ‘Tofaahi’, were evaluated under three irrigation regimes 100% ETc, 75% ETc, and 50% ETc. Characteristics of shoot and root, as well as physio-chemical constituents, were determined. Besides, the gene expression of dehydration-responsive element binding (DREB), dehydrin (DHN), and catalase (CAT) genes in olive cultivars were explored under different irrigation regimes. The results indicated a substantial impact of irrigation level on all studied parameters. The mild and extreme drought stress treatments caused a gradual reduction in nitrogen, phosphorus, and potassium content, relative water content, root and shoot length, root and leaf numbers, branch count, and leaf area across both seasons. Conversely, proline content was considerably increased under drought treatments compared to well-watered conditions. Similarly, the assessed cultivars exhibited significant variation in all studied parameters, with ‘Eggizi-Shami’ demonstrating superiority. Under mild and extreme drought stress conditions, the cultivar ‘Eggizi-Shami’ displayed the highest proline content and most growth characteristics. Besides, the real-time quantitative PCR (RT-qPCR) analysis displayed significant alterations in gene expression of the tested three genes related to drought response (DHN, DREB, and CAT). The RT-qPCR analysis revealed that under drought stress conditions (75% and 50% ETc), ‘Eggizi-Shami’ exhibited higher expression compared to the other two cultivars (‘Tofaahi’ and ‘Manzanillo’). Combining the results of morphological and physiological parameters with gene expression analysis of drought-related genes can offer highly validated information about drought-tolerant olive cultivars. This integrated approach serves as an innovative methodology to identify and confirm genes involved in abiotic stress.
Significance of selenium in ameliorating the effects of irrigation deficit via improving photosynthesis efficiency, cell integrity, osmo-protectants, and oil profile of anise crop
Authors: RAMADAN Khaled M.A. , EL-BELTAGI Hossam S. , ABD EL MAGEED Taia A. , MAZROU Khaled E. , MOHAMED Gamal F. , EL-SAADONY Mohamed. T. , EL-SAADONY Fathy M.A. , ROBY Mohamed H.H. , SAUDY Hani S. , ABOU-SREEA Alaa I.B.
Published: December 2023

Anise is one of the plants with therapeutic potential, which is classified among the most important medicinal plants with interesting biological effects. Its components could be perceived so as “natural” and “safe” alternatives to antibiotics as well as they are applied in different industries such as food and cosmetic purposes. Selenium (Se) is an essential micronutrient, however, its importance to improve oil yield and quality of anise has not been adequately investigated, specifically under drought. Therefore, two successive seasons were conducted to investigate the effect of selenium foliar application upon anise plants under drought stress. Selenium was applied at three different concentrations (0.0 1.0 and 2.0 mM denoted Se0, Se1 and Se2, respectively) along with two levels of crop evapotranspiration (ET): Full irrigation, 100% of ET (FI) and 60% of ET (DI). The promotive effect of combinations of DI × Se1 or Se2 (for Fv/Fm, RWC%, and MSI% in the first season) and DI × Se2 (for Fv/Fm, and MSI% in the second season) were as similar as FI × Se2. Compared to the counterpart control treatment (DI × Se0), the highest increases in total free amino acids (31.5 and 31.6%), total soluble sugars (84.2 and 86.4%) and free proline content (84.2 and 86.4%) were recorded with application of DI × Se2 practice in both seasons, respectively. Under DI, Se2 recorded the maximum values of root length, shoot fresh weight and shoot dry weight in the second season. Under drought, the increases in seed yield due to application of Se1 and Se2 amounted to 1.72 and 1.62 folds in the 1st season and 1.50 and 1.43 folds in 2nd one, respectively. The most effective practice for improving IWUE was Se1× DI in both seasons, followed by Se2 × DI. Based on the chromatographical detection, the maximum values of Anethole were recorded with FI × Se2 while L-Linalool has greatly increased with DI × Se2. In conclusion, the growers in arid and semi-arid zones are advised to use selenium (2.0 mM) in anise fertilization to mitigate the adverse impacts of drought, and keeping crop yield and quality.
Atualização dos rastreadores para detecção de eventos adversos a medicamentos em pacientes hematológicos
Authors: Domingues Íris Pilegi , Costa Milene Rangel da
Published: December 2023

Resumo: A utilização de rastreadores para a busca ativa e detecção de eventos adversos a medicamentos (EAM) tem ganhado espaço nos serviços de farmacovigilância. Assim, o objetivo principal do estudo foi propor uma nova lista de rastreadores para ser empregada em um centro especializado em hematologia do Rio de Janeiro, Brasil. A atualização da lista de rastreadores consistiu na revisão da lista atual, com a exclusão e inclusão de rastreadores. Para verificar o desempenho da nova lista de rastreadores, realizou-se um estudo transversal em que os novos rastreadores foram utilizados para investigar a ocorrência de EAM em pacientes atendidos na emergência ou hospitalizados no período de janeiro a março de 2022. Para cada suspeita de EAM identificada, caracterizaram-se o perfil do paciente e as reações adversas a medicamentos (RAM) quanto à causalidade e gravidade. O desempenho dos rastreadores e sua capacidade de captação de EAM foram calculados por meio dos indicadores: frequência do rastreador por 100 prontuários, frequência de EAM por 100 prontuários e valor preditivo positivo (VPP). Para avaliar o desempenho global da nova lista proposta, calculou-se o VPP. Foram identificadas 374 prescrições de rastreadores em 186 prontuários. Os mais eficientes na detecção de possíveis EAM foram: lidocaína, loperamida, bisacodil, filgrastim e clister de glicerina. O VPP global da nova lista sugerida foi 48% contra 10% da lista anterior. Este estudo demonstrou a importância de uma lista de rastreadores atualizada para o monitoramento dos EAM e o aprimoramento da assistência prestada.
Immunoexpression of HSP27 does not seem to influence the prognosis of oral tongue squamous cell carcinoma
Authors: Torres Ondina Karla Mousinho Rocha , Silva Luiz Arthur Barbosa da , Freitas Roseana de Almeida , Silveira Éricka Janine Dantas da , Miguel Márcia Cristina da Costa
Published: December 2023

Abstract New methods of early detection and risk assessment have been studied aiming to predict the prognosis of patients and directing a specialized treatment of the oral tongue squamous cell carcinoma (OTSCC). In this context, several molecular biomarkers have been investigated for this purpose, and, among them, the heat shock protein 27 (HSP27) can be named. The study aimed to analyze whether heat shock protein 27 (HSP27) exerts any influence on OTSCC, correlating its immunoexpression with clinicopathological parameters, and patient survival. The sample comprised 55 OTSCC cases and 20 normal oral mucosa specimens. The malignancy grading systems proposed by the WHO in 2005, Brandwein-Gensler et al., and Almangush et al. were applied in a histomorphological study. HSP27 expressions were evaluated through the Immunoreactivity Score System (IRS). Significant values were considered at p <0.05 for all statistical tests. Higher IRS results were observed for normal oral mucosa specimens when compared to OTSCC cases (p <0.001). No significant associations between HSP27 immunostaining, the analyzed clinicopathological parameters and patient survival were observed. The results of the present study indicate lower HSP27 expression in OTSCC cases compared to normal oral mucosa specimens. Thus, HSP27 expression does not seem to influence patient prognosis.
Effects of the application of sodium ascorbate after in-office bleaching on the penetration of hydrogen peroxide, color change, and microtensile bond strength
Authors: Mena-Serrano Alexandra , Granda-Albuja María G. , Naranjo Jenny , Fierro Eliana Aldás , Favoreto Michael Willian , Loguercio Alessandro D. , Reis Alessandra
Published: December 2023

Abstract This study aimed to evaluate the effects of the application of 10% sodium ascorbate (SA) after in-office bleaching on the penetration of hydrogen peroxide (HP) into the pulp chamber, color change, and microtensile bond strength (µTBS) to the resin-enamel interface. Thirty premolars and thirty molars were randomly divided into three groups (n = 20 each). One group was exposed to deionized water (negative control). The other two groups were bleached with 35% HP in a single session for 3x15 minutes for each application. However, in only one of them, SA was applied for 10 minutes after bleaching. After, the concentration (µg/mL) of HP in each pulp chamber was evaluated by UV-Vis spectrophotometry. Color changes (ΔEab, ΔE00, and ΔWID) were evaluated with a digital spectrophotometer before and in the first week after bleaching. After treatment, molars were restored and sectioned to obtain resin-enamel interface sticks for µTBS at a crosshead speed of 1 mm/min until failure. The HP concentration and µTBS data were analyzed using one-way ANOVA and Tukey tests, and color changes were analyzed by t-tests (α = 0.05). SA application significantly improved the µTBS values and reduced the HP concentrations within the pulp chambers (p < 0.0001). The application of SA significantly interfered with the color changes after bleaching when compared to the control group (p < 0.05). Application of 10% SA after in-office bleaching successfully reduced the penetration of HP into the pulp chamber; however, it decreased color change.
Fluoride-modified implant surfaces improves osseointegration in the tibias of rats with induced diabetes
Authors: Oliveira Guilherme José Pimentel Lopes de , Fontanari Lucas Amaral , Souza João Antônio Chaves de , Spin-Neto Rubens , Elias Carlos Nelson , Marcantonio Junior Elcio , Orrico Silvana Regina Perez
Published: December 2023

Abstract This study evaluated the influence of a fluoride-modified titanium surface on osseointegration in rats with induced diabetes. One hundred and eighty rats were randomly allocated into 3 groups with 60 animals each: Control group (C): Animals without diabetes; Diabetes Group (D): Animals with uncontrolled induced diabetes; Controlled Diabetes Group (CD): Animals with diabetes induced controlled by the insulin administration. Diabetes was induced by streptozotocin injection. Each animal received 2 implants in the proximal tibial metaphysis, one with the machined surface (M) and the other one with a fluoride-modified titanium surface (F), after 4 weeks of induction of diabetes. The animals were submitted to euthanasia 2, 4, and 6 weeks after the implant placement (n = 20 animals/group). The osseointegration was evaluated by the implant removal torque test and the histometric analysis of the non-decalcified histological sections: 1) Contact bone/implant (%BIC); 2) Bone tissue area between implant threads (%BBT). Implants with F surface showed a higher removal torque than implants with surface M in all groups. There was no difference in %BIC between the groups regardless of the surface used. The F surface showed a tendency to present higher %BBT values for the 3 evaluation periods in the D group. The fluoride-modified implant surface has no impact on the %BIC and %BBT. However, the fluoride-modified implant surface increases the locking of the implants with the bone. The hyperglycemia was associated with lower removal torque values despite the surfaces of the implant used.
Higher immunoexpression of CK14 from the Wnt-1/β-catenin pathway in the development of odontomas
Authors: França Glória Maria de , Carlan Leonardo Magalhães , Pires Hévila de Figueiredo , Oliveira Cláudia Nunes de , Santos Pedro Paulo de Andrade , Galvão Hébel Cavalcanti
Published: December 2023

Abstract Tooth development depends on a series of reciprocal signaling interactions between the oral epithelium and ectomesenchyme. This study aimed to investigate the role of CK14, a protein involved in Wnt-1/β-catenin signaling, in odontogenesis and the development of odontomas. This cross-sectional, retrospective, immunohistochemical study analyzed 30 compound odontomas, 30 complex odontomas, and 17 tooth germs. Higher immunoexpression of CK14 was observed in odontogenic epithelial cells of tooth germs (p < 0.001) and odontogenic epithelial cells of odontomas (p < 0.001). There was higher immunoexpression of Wnt-1 and β-catenin proteins in epithelial cells of tooth germs (p = 0.002 and p < 0.001, respectively), as well as in the ectomesenchyme of odontomas (p = 0.003 and p < 0.001, respectively). β-Catenin was moderately and significantly correlated with CK14 in the membrane of reduced enamel epithelial cells in odontomas (p = 0.007). Higher immunoexpression of CK14 was observed in the odontogenic epithelium during the bud and cap stages and lower immunoexpression in the internal enamel epithelium during the bell stage. In odontomas, lower expression of Wnt-1/β-catenin and higher immunoexpression of CK14 were found in odontogenic epithelial cells, especially adjacent to the mineralized material resembling the tooth formed in these lesions.
Long-term effect of firing protocols on surface roughness and flexural strength of lithium disilicate glass-ceramic
Authors: Lima Kaíssa da Cunha , Vivanco Rocio Geng , Rodrigues Pedro Roberto Braz , Caetano Ana Lúcia Pereira , Pires-de-Souza Fernanda de Carvalho Panzeri
Published: December 2023

Abstract This study evaluated the effect of different firing protocols on the surface roughness and flexural strength of CAD/CAM lithium disilicate glass-ceramic (LD) after aging methods. Forty-two LD bars of 16 x 4 x 2 mm (IPS e-max CAD, Ivoclar) were randomly separated into two groups according to firing protocols: Single firing-Staining, glazing, and crystallization in a single step; Multiple firings-Crystallization+First staining+Firing+Second staining+Firing+Glazing+Firing. After protocols, initial surface roughness readings were taken (Surfcorder SE1700, Kosakalab). Samples were then randomly separated into three groups (n=7) according to the aging methods they were submitted: Thermomechanical cycling (TMC, ER System, Erios, 1,200,000 cycles, 0.3 MPa, 2 Hz and 5°C/37°C/55°C, 30 s swell time); Simulated toothbrushing (STB, Pepsodent, MAVTEC, 73,000 cycles), and Control (no aging). Final surface roughness readings were done, and samples were submitted to a three-point bending test (OM100, Odeme Dental Research) and fractographic analysis by scanning electron microscopy (EVO-MA10, ZEISS). Data were analyzed (2-way ANOVA, (α=.05). There was no difference (p>.05) in the flexural strength between the firing protocols, regardless of the aging method. STB decreased the flexural strength of samples submitted to multiple firings, different from control (p<.05). Without aging (Control), before TMC, and after STB, LD had lower surface roughness when submitted to multiple firings than to single firing (p<.05). The firing protocols did not affect the flexural strength or the surface roughness of the lithium disilicate glass-ceramic, even after aging. However, toothbrushing negatively affected the flexural strength and smoothed the surface of the ceramic submitted to multiple firings.
Do different adhesives influence the color stability and fluorescence of composite restorations after aging?
Authors: Souza Claudia Simoes de , Silva Thamirys da Costa , Tsutsumi Mariana Sati Cantalejo , Lima Glivia Queiroz , Queiroz Mariana Elias , Strazzi-Sahyon Henrico Badaoui , Maluly-Proni Ana Teresa , Briso Andre Luiz Fraga , Santos Paulo Henrique dos
Published: December 2023

Abstract This study aimed to evaluate the influence of dental adhesive color on the chromatic stability and fluorescence intensity of composite resin restorations of different thicknesses. Ninety bovine enamel samples were obtained and restored with resin composite varying thicknesses of restorative material and enamel (1.0 mm enamel and 1.0 mm composite; 1.5 mm enamel and 0.5 mm composite; 0.5 mm enamel and 1.5 mm composite). The restorations were made of composite resin (Opallis E-bleach H) using different types of dental adhesives: Ambar, Ambar APS, and Single Bond Universal (n=10). The samples were subjected to color measurement tests in a spectrophotometer using CIEDE2000 and fluorescence intensity measurements before and after aging in a red wine coloring solution. Data were subjected to analysis of variance (ANOVA) and Tukey's test (α = 0.05). There were no statistically significant changes in color stability or fluorescence intensity for restorations made of different materials or thicknesses (p>0.05). Single Bond Universal showed greater color stability at 0.5 mm thickness (ΔE00 = 4.4 ± 1.6) compared to other thicknesses of the same material (p=0.003), as well as a greater difference in fluorescence intensity after aging at 1.5 mm thickness (-414.9 ± 103.8) compared to other materials (p=0.0002). Overall, it was concluded that the different adhesive systems did not influence the color stability and fluorescence of restorations of different thicknesses.
Chemical analysis of mineral trioxide agregate mixed with hyaluronic acids as an accelerant
Authors: Ahmed Muthanna S. , Hasan Nadia H. , Saeed Mohammed. G.
Published: December 2023

Abstract Mineral trioxide aggregate (MTA) has many clinical applications in dentistry; the main drawback is the long setting. The main objective is to investigate and compare the chemical effect of using two commercially available hyaluronic acid hydrogels (HA) instead of distilled water for mixing MTA as an accelerant of setting time. Materials and method: Test materials were divided into three groups; Group 1: (control) mixing MTA with distilled water supplied by the manufacturer; Group 2: mixing MTA with a hybrid cooperative complex of high and low molecular weight HA (Profhilo®); Group 3: mixing MTA with High molecular weight / non-cross-linked HA (Jalupro®). Mixing time, and setting time (initial and final) were determined, Fourier-transform infrared spectroscopy, Energy-dispersive X-ray spectroscopy, Field emission Scanning Electron Microscopy, and X-ray diffraction were performed. Results: mixing time, initial, and final setting time for (MTA + HA) groups were significantly different and lower in comparison to the control group (p < 0.05). This study revealed higher expression of calcium silicate hydrate and calcium hydroxide expression with higher Ca release in the MTA + HA group than the control group. Conclusion: commercially available HA demonstrated better chemical properties when used as a mixing medium for MTA. The Mixing and setting time for MTA + HA group were significantly shorter than those of the control group were. Thus, commercially available HA can be used as a mixing medium for MTA.
Seeking treatment for traumatic dental injuries in schoolchildren: A multilevel analysis
Authors: Bernardino Veruska Medeiros Martins , Lima Larissa Chaves Morais de , Araújo Luiza Jordânia Serafim de , Neves Érick Tássio Barbosa , Ferreira Fernanda de Morais , Granville-Garcia Ana Flávia
Published: December 2023

ABSTRACT To investigate individual and contextual factors associated with seeking treatment for traumatic dental injuries. A cross-sectional study was conducted with 739 pairs of guardians and children. Guardians answered a questionnaire addressing sociodemographic characteristics, seeking treatment for a tooth injury in the child, and the Oral Health Literacy-Adult Questionnaire. Descriptive analysis and unadjusted and adjusted multilevel Poisson regression analysis (p<0.05). The prevalence of seeking treatment for traumatic dental injury was 44.7%. Sociodemographic variables associated were white skin of the child (PR = 1.30; 95% CI: 1.08-1.76), mother’s age older than 35 years (PR = 1.70; 95% CI: 1.50-1.90), married parents (PR = 1.93; 95% CI: 1.70-2.23), guardians with more than eight years of schooling (PR = 2.00; 95% CI: 1.76-2.23), with adequate oral health literacy (PR = 3.33; 95% CI: 3.01-3.62) and the daily use of electronic devices by the child (PR = 1.26; 95% CI: 1.02-1.50). On the contextual level, attending a private school (PR = 1.77; 95% CI: 1.02-3.05) and the number of primary care units with oral health teams in the school district (PR = 1.78; 95% CI: 1.12-2.38) remained associated. Among the children who suffered TDI, adequate oral health literacy on the part of the parents stood out among the factors associated with seeking treatment.
Leadership through a gender lens: Disparities in Dental Research
Authors: Gatti-Reis Luisa , Mattos Flávio Freitas , Pordeus Isabela Almeida , Martins-Júnior Paulo Antônio , Coutinho Danielle Carvalho de Oliveira , Perazzo Matheus França , Paiva Saul Martins
Published: December 2023

Abstract This study aimed to analyze the 100 most-cited papers in Dentistry, with a focus on female leadership in dental research. Papers were retrieved from the Web of Science Core Collection (WoS- CC) in the category ‘Dentistry, Oral Surgery & Medicine’. Gender was assessed through WoS-CC, Scopus, ResearchGate, social media, institutional websites, and software that assigns gender according to first names (https://genderapi.io). Characteristics of authors in leadership roles were retrieved, such as affiliation, publication history, citations, H factor, and i500. The 100 most-cited papers in Dentistry were authored by 394 researchers, 326 (82.7%) men, and 68 (17.3%) women - there were 4.8 male authors for each female. Among the lead authors, there were 11.3 males for each female. Among female senior authors, there were 7 males for each female. Among lead/senior authors of the 100 most-cited papers (first and last authors, respectively), 18 were women. There was an increase in the participation of women in the top cited papers regardless of authorship role across the six decades, with a peak of two female authors in the first decade of the 21st century. For female authors in leadership roles, their publication history shows the time between their first and last papers in WoS-CC ranged from 4 to 42 years for lead authors and 1 to 39 years for senior authors. Women were found to be largely underrepresented as leaders of the 100 most-cited papers, highlighting pervasive gender inequalities in dental research publications.
Physical-chemical influences and cell behavior of natural compounds on titanium dental surfaces
Authors: Maquera-Huacho Patricia Milagros , Carvalho Gabriel Garcia de , Jafelicci Júnior Miguel , Marcantonio Junior Elcio , Spolidorio Denise Madalena Palomari
Published: December 2023

Abstract The present study evaluated the influence of carvacrol, terpinene-4-ol, and chlorhexidine on the physical-chemical properties of titanium surfaces, cell viability, proliferation, adhesion, and spreading of fibroblasts and osteoblasts in vitro. Titanium surfaces (Ti) were treated with Carvacrol (Cvc), Terpinen-4-ol (T4ol), Chlorhexidine (CHX), DMSO, and ultrapure water (Control group). Physical-chemical modifications were evaluated by surface wettability, the surface free energy (SFE) calculated from the contact angle values using the Owens-Wendt-Rabel-Kaeble (OWRK) equation, scanning electron microscopy (SEM) and energy dispersive spectrometry probe (EDS) system. Cells were seeded onto Ti-treated surfaces and incubated for 24 h and 72 h, then evaluated by Alamar blue assay and fluorescence microscopy. Surfaces treated with Cvc and T4ol showed the presence of Na, O, and Cl. All surfaces showed hydrophilic characteristics and SFE values between 5.5 mN/m and 3.4 mN/m. On the other hand, EDS peaks demonstrated the presence of O and Cl after CHX treatment. A reduction of cell viability and adhesion was noted on titanium surfaces treated with CHX after 24 and 72h. In conclusion, the results indicate that the decontamination with Cvc and T4ol on Ti surfaces does not alter the surface proprieties and allows an adequate interaction with cells involved in the re-osseointegration process such as fibroblasts and osteoblasts.
Fluorotic Enamel Susceptibility to Dental Erosion and Fluoride Treatment
Authors: Silva Cristiane Araújo Maia , Sousa Frederico Barbosa de , Martinez-Mier Esperanza Angeles , Vieira Basílio Rodrigues , Nascimento Johnatan Meireles do , Hara Anderson Takeo
Published: December 2023

Abstract The purpose of this in vitro study was to test the hypothesis that fluoride treatment can prevent dental erosion on fluorotic enamel of different severities. It followed a 3×2 factorial design, considering a) fluorosis severity: sound (TF0, Thylstrup-Fejerskov Index), mild (TF1-2), moderate (TF3-4); and b) fluoride treatment: 0 (negative control) and 1150ppmF. Human molars with the three fluorosis severities (n=16, each) were selected and randomly assigned to the two fluoride treatments (n=8). Enamel blocks (4×4mm) were prepared from each tooth and subjected to a dental erosion cycling model, for 10 days. The daily cycling protocol consisted of erosive challenges (1% citric acid, pH 2.4), interspersed by periods of immersion in artificial saliva, and three 2-minute treatments with either 0 or 1150ppm F. The enamel volume loss (mm3) was calculated by subtracting values obtained by microtomography before and after cycling. Two-Way ANOVA showed no significant interaction between fluorosis severity and fluoride treatment (p=0.691), and no significant effect for either fluorosis severity (TF0 mean±standard-deviation: 13.5(10-2±0.42(10-2, TF1-2: 1.50(10-2±0.52(10-2, TF3-4: 1.24(10-2±0.52(10-2, p=0.416) or treatment (0ppmF: 1.49(10-2±0.53(10-2; 1150ppmF: 1.21(10-2±0.42(10-2; p=0.093), when evaluated independently. Considering the limitations of this in vitro study, the presence and severity of fluorosis in enamel do not appear to affect its susceptibility to dental erosion. Fluoride treatment was not effective in preventing the development of dental erosion in both sound and fluorotic enamel substrates under our experimental conditions.
Microleakage of chairside moulded, 3D-printed and milled provisional restorations using a curve-fit approach
Authors: Reyes Keshia , Plaksina Polina , Barazanchi Abdullah , Vuuren Wendy-Ann Jansen van , Waddell J Neil , Li Kai Chun
Published: December 2023

Abstract The purpose of this study was to evaluate and measure the microleakage inhibiting quality of provisional restorations manufactured using computer-aided manufacturing, 3D printing, and chairside molded provisional restorative materials. Fifteen provisional restorations each from 3D printed, milled, and chairside molded were manufactured. All restorations were cemented onto sintered zirconia abutment dies and adhered with zinc-oxide non-eugenol temporary cement. Artificial aging was conducted by thermocycling for 800 cycles to simulate 1 month of clinical use. All specimens were submerged in 2% (w/w) methylene blue for 24 hours at 37°C, sectioned, and analyzed digitally for the distance of dye penetration through image analysis. The data were analyzed using the Kruskal-Wallis test with Dunn-Bonferroni post-hoc. Significant differences in dye penetration depth were observed between all groups except milled vs chairside molded. Light microscopy revealed differences in mean cement thickness for 3D printed, milled, and chairside molded of 83.6 µm (1σ = 31.9 µm), 149.1 µm (1σ = 88.7 µm) and 137.9 µm (1σ = 67.2 µm) respectively. Conclusion: 3D printed provisional restorations were found to have the least amount of microleakage compared to milled and chairside molded provisional restorations.
Microbial-inoculated remineralizers as source of potassium and other nutrients
Authors: Assunção Rodolfo D. V. da , Cassol Paulo C. , Granados Sabrina B. , Mafra Álvaro L. , Bittencourt Ricardo F. P. de M.
Published: December 2023

ABSTRACT The consumption of potassium (K) fertilizers in Brazilian agriculture exceeds the national production of this input by more than ten times, indicating the need for alternatives to reduce imports of these products. The objective of this study was to evaluate the performance of the remineralizing rocks phonolite and olivine melilitite as sources of K and other nutrients, as well as the effects of inoculation with Bacillus subtilis and Bacillus megaterium on the solubilization of these rocks in the soil. A greenhouse experiment was conducted using a randomized block design, with four replications, in a factorial arrangement consisting of three K sources (potassium chloride, phonolite, and olivine melilitite), three rates (150, 300, and 600 kg ha-1 K2O), with and without inoculant, and two controls without K (one with and one without inoculant). The experimental units consisted of pots containing 3 kg of soil and a strawberry plant grown for eight months. The treatment with olivine melilitite inoculated with rhizobacteria favored phosphate solubilization when applied the highest rate. Olivine melilitite remineralizer, alone or inoculated with rhizobacteria, increased K+ and Ca2+ contents in the soil when applied at the intermediate and highest rates (300 and 600 kg ha-1 K2O), highlighting this remineralizer as an alternative potassium source for plants.
Pressure injury prevention measures: overview of systematic reviews
Authors: Pott Franciele Soares , Meier Marineli Joaquim , Stocco Janislei Giseli Dorociaki , Petz Francislene de Fátima Cordeiro , Roehrs Hellen , Ziegelmann Patricia Klarmann
Published: December 2023

ABSTRACT Objective: Summarizing the evidence from systematic reviews regarding the comparison the effectiveness of interventions to prevent pressure injuries. Method: Overview of systematic reviews conducted in accordance with Cochrane guidelines. A search was performed in databases, repositories and systematic review registration sites. Results: 15 reviews were included in this overview. The sensitivity analysis showed a reduction in the incidence of pressure injuries with nutritional supplementation compared to the standard hospital diet (Relative Risk (RR) = 0.83; 95% Confidence Interval (CI): 0.72–0.95). There was evidence of the superiority of constant low-pressure surfaces (RR = 0.38; 95% CI;0.24–0.61), alternating pressure devices (RR = 0.31; 95% CI:0.17–0.58) and alternative foams (RR = 0.40; 95% CI:0.21–0.74) when compared to the standard hospital mattress or standard foam. The use of a silicone cover reduced the incidence of pressure injuries by 75% (RR = 0.25; 95%CI:0.16–0.41) when compared to no cover. Conclusion: Although some interventions have been shown to be effective in reducing the incidence of pressure injury, the evidence is limited or very limited and subject to change. Registration CRD42017064586.
Medidas de prevenção de lesão por pressão: overview derevisões sistemáticas
Authors: Pott Franciele Soares , Meier Marineli Joaquim , Stocco Janislei Giseli Dorociaki , Petz Francislene de Fátima Cordeiro , Roehrs Hellen , Ziegelmann Patricia Klarmann
Published: December 2023

RESUMO Objetivo: Sumarizar as evidências de revisões sistemáticas sobre a comparação da efetividade de intervenções para prevenção de lesão por pressão. Método: Overview de revisões sistemáticas conduzida de acordo com as recomendações Cochrane. Realizou-se busca em bases de dados, repositórios e site de registro de revisões sistemáticas. Resultados: Foram incluídas 15 revisões nesta overview. A análise de sensibilidade demonstrou redução na incidência de lesão por pressão com a suplementação nutricional comparada a dieta hospitalar padrão (Risco Relativo (RR) = 0,83; Intervalo de Confiança(IC) 95%:0,72–0,95). Evidenciaram-se superioridade das superfícies de baixa pressão constante (RR = 0,38; IC 95%;0,24–0,61), dos dispositivos de pressão alternada (RR = 0,31; IC95%:0,17–0,58) e das espumas alternativas (RR = 0,40; IC95%:0,21–0,74) quando comparadas ao colchão hospitalar padrão ou de espuma padrão. O uso de cobertura de silicone reduziu em 75% a incidência de lesão por pressão (RR = 0,25; IC95%:0,16–0,41) quando comparada a nenhuma cobertura. Conclusão: Embora algumas intervenções demonstrem-se efetivas na redução da incidência da lesão por pressão, as evidências são limitadas ou muito limitadas e sujeitas a alteração. Registro CRD42017064586.
Effects of SARS-CoV-2 infection on health and functional capacity in institutionalized older adults
Authors: Queiroz Bárbara Lima , Nascimento Carlos Queiroz do , Souza Thamires Otaviano Marques de , Bádue Gabriel Soares , Bueno Nassib Bezerra , Vasconcelos Sandra Mary Lima , Mello Carolina Santos , Ribeiro-Andrade Müller , Ataíde Terezinha da Rocha , Barros-Neto João Araújo
Published: December 2023

ABSTRACT Objective: To assess the effect of SARS-CoV-2 infection on the health conditions and functional capacity of older adults living in long-term care units in Maceió City – Alagoas State. Methods: A prospective cohort was conducted with institutionalized older adults of both sexes. Older adults were assessed for clinical conditions (diagnosis of chronic diseases and biochemical tests), functional capacity, and nutritional status. All assessments were repeated on two occasions, maintaining a 6-month interval between them. Results: The sample was composed of 289 older adults. Of the total, 98 (33.9%) were positive for COVID-19 and eight died (2.8%). Men were more likely to have COVID-19 (OR = 3.50; p < 0.01). It was observed that the disease contributed to increasing the frequency of dependent older adults after six months (OR = 1.38; p-interaction < 0.01). It was also observed that after six months of positive diagnosis for COVID-19, there was greater weight loss (p < 0.01), reduced BMI (p < 0.01), increased mean SBP (p = 0.04), and DBP (p = 0.03). Conclusion: Effects of COVID-19 in institutionalized older adults go beyond acute complications and compromise blood pressure control, functional capacity, and favor weight loss.
Continuing education on child development in primary care: healthcare workers’ perspectives
Authors: Sousa Rute Costa Régis de , Paula Weslla Karla Albuquerque Silva de , Alves Fabia Alexandra Pottes , Albuquerque Maria Ilk Nunes de , Albuquerque Grayce Alencar , Coriolano-Marinus Maria Wanderleya de Lavor
Published: December 2023

ABSTRACT Objective: To analyze the contributions of a continuing education with Primary Health Care professionals that promotes child development. Method: A continuing education intervention, utilizing a qualitative approach, was conducted among healthcare workers at a Primary Health Care facility in a low-income neighborhood in the city of Recife. The intervention consisted of eight workshops conducted between July and October 2019, with the participation of fifteen healthcare workers. All data from the focus groups were recorded, transcribed, and analyzed thematically using Bronfenbrenner’s bioecological model as the theoretical framework. Results: Through the continuing education intervention, healthcare professionals were able to reflect on their work processes and personal lives and propose actions to improve child development. Conclusion: The study findings highlight the significant impact of such interventions in changing perceptions and professional practices related to child development. Overall, this research provides valuable insights into the effectiveness of continuing education interventions for promoting healthy child development in primary care settings.
INFLUÊNCIAS DA ESFERA AFETIVO-RELACIONAL COM O PARCEIRO NO ENGRAVIDAR INTENCIONADO DE ADOLESCENTES
Authors: Silva Ana Maria Nunes da , Corrêa Áurea Christina de Paula , Mandú Edir Nei Teixeira , Gaíva Maria Aparecida Munhoz , Teston Elen Ferraz , Vieira Viviane Cazetta de Lima , Dalprá Luanna de Arruda e Silva , Marcon Sonia Silva
Published: December 2023

RESUMO Objetivo: compreender influências interconexas no engravidar intencionado de adolescentes a partir de particularidades da esfera afetivo-relacional com o parceiro. Método: estudo qualitativo-interpretativo, realizado com 16 adolescentes grávidas residentes em um bairro de baixo nível socioeconômico, em uma capital do centro-oeste brasileiro. Os dados foram coletados em 2019 mediante entrevistas em profundidade, com uso complementar dos recursos autorretrato, mapa relacional e foto-elicitação, submetidos à Análise de Conteúdo Temática. Resultados: a intenção-ação das adolescentes voltada ao engravidar sustentou-se na apreciação do status e da qualidade da relação amorosa com o parceiro quanto aos aspectos casamento/união, vínculo-compromisso, parceria-proteção financeira e boa interação-amor. Estas exprimiram necessidades de vínculo afetivo e de segurança material por elas vividas, particularidades psíquicas da sua fase de desenvolvimento, além de representações sociais construídas sobre a relação conjugal, amorosa e do ser homem e mulher na família. De forma conexa refletiram sobre condições sociais e relações em família vividas, além de absorções do ideal cultural do amor romântico e de gênero. Conclusão: na saúde reprodutiva de adolescentes, é indispensável considerar as influências afetivas no engravidar, sem descolá-las das inserções sociais e em família daquelas, bem como dos seus modos de exercer a agência de suas trajetórias afetivo-sexuais.
AÇÕES, EMOÇÕES E ATOS NO PROCESSO DE BUSCA DA INFORMAÇÃO: UM ESTUDO DO COMPORTAMENTO INFORMACIONAL DOS ALUNOS DE CIÊNCIAS BIOLÓGICAS DA UFRPE
Authors: Silva Vania Ferreira da , Teixeira Maria do Rocio Fontoura
Published: December 2023

RESUMO A pesquisa teve como objetivo analisar o comportamento informacional, na perspectiva do processo de busca da informação, dos discentes das licenciaturas em Ciências Biológicas da Universidade Federal Rural de Pernambuco. Do tipo quali-quantitativa, quanto aos meios, trata-se de uma pesquisa de campo e, quanto aos fins, uma pesquisa descritiva. O corpus analisado foi de alunos das Licenciaturas de Ciências Biológicas que cursavam do 6º ao 10º período. Como procedimentos metodológicos foram adotados o levantamento bibliográfico, a análise documental, a entrevista e o questionário. Para análise dos resultados, utilizou-se o modelo de processo de busca de informação de Kuhlthau (1991) e o marco do letramento informacional da ACRL (2016). Como resultado percebe-se que o processo de busca de informação dos alunos é realizado de forma irrefletida e através do pouco conhecimento que adquiriram durante sua formação. No que diz respeito aos sentimentos, os alunos das Ciências Biológicas apresentaram baixos índices de sentimentos como dúvida e insegurança. Considera-se que os alunos mostraram aptos para o uso de instrumentos de busca, como os conhecidos buscadores da internet, mas demonstram insegurança para desenvolver as etapas do processo de busca de informação.
ESTRATÉGIAS DE AVALIAÇÃO DA PRODUÇÃO CIENTÍFICA: REFLEXÕES SOBRE SUAS LIMITAÇÕES E COMPLEMENTARIDADES
Authors: Barata Rita Barradas
Published: December 2023

RESUMO O ensaio foi construído a partir da análise da literatura pertinente e da experiência da autora em processos avaliativos da política científica, avaliação de programas de pós-graduação estrito senso e na atividade editorial em periódicos científicos publicados no país e no exterior. A avaliação da produção científica através dos artigos científicos tem duas grandes vertentes principais: a avaliação dos artigos em si e a avaliação dos periódicos nos quais eles são publicados. Na avaliação dos artigos em si, podem ser usadas fundamentalmente três estratégias distintas e complementares: a classificação segundo características formais do artigo, a contagem das citações recebidas, e a avaliação qualitativa baseada nos procedimentos de peer review pós-publicação. Na avaliação dos periódicos como indicadores indiretos da qualidade da produção, utilizam-se diferentes indicadores bibliométricos, seja como fator de ponderação dos artigos, seja como critérios para construir classificações como o Qualis periódicos da CAPES. Como em toda questão complexa, não pode haver uma única forma de realizar a avaliação e, o uso de diferentes estratégias pode contrabalançar limitações existentes em cada uma delas, dando uma perspectiva mais abrangente e multifacetada para os avaliadores.
Hábitos de sono e autoavaliação miofuncional orofacial de crianças com risco para distúrbios respiratórios do sono
Authors: Picinato-Pirola Melissa , Lira Amanda Lima e , Viana Giovanna Régis , Santos Thaynara Lemos Batista , Corrêa Camila de Castro
Published: December 2023

RESUMO Objetivo Identificar e correlacionar as queixas de alterações miofuncionais orofaciais e de risco para distúrbios respiratórios do sono com hábitos de sono na infância. Método Participaram 71 pais ou responsáveis de crianças de 6 a 11 anos, matriculadas em uma escola pública. Foi aplicado um formulário com questões semiestruturadas/anamnese e os protocolos Nordic Orofacial Test-Screening - entrevista, Pediatric Obstructive Sleep Apnea Screening Tool Questionnaire, e Children’s Sleep Habits Questionnaire - todos em suas versões em português/Brasil no formato online. Para a análise estatística, realizou-se o teste de correlação de Spearman, considerando o nível de significância de 5%. Resultados 29 crianças eram do sexo feminino (40,8%) e 42 do sexo masculino (59,2%), com média de idade de 8,52 anos. As queixas miofuncionais orofaciais encontradas foram relacionadas às funções de respiração (35,2%), mastigação e deglutição (32,4%) e hábitos deletérios (33,8%). Todas as crianças apresentaram um baixo risco para distúrbios respiratórios do sono e quanto aos hábitos de sono, 23 crianças (32,39%) apresentaram uma somatória menor, enquanto que 48 crianças (67,61%) ultrapassaram 41 pontos. Conclusão Houve correlação entre risco para distúrbios respiratórios do sono em crianças com as queixas de alterações miofuncionais orofaciais e com a baixa qualidade/maus hábitos de sono.
Modificações do feedback auditivo e seus efeitos sobre a voz de indivíduos adultos: uma revisão de escopo
Authors: Alves Moisés do Carmo , Mancini Patrícia Cotta , Teixeira Leticia Caldas
Published: December 2023

RESUMO Introdução A percepção auditiva da voz e sua produção envolvem o feedback auditivo, as pistas cinestésicas e o sistema de feedforward, os quais produzem efeitos distintos para a voz. Os efeitos Lombard, Sidetone e o Pitch-Shift-Reflex são os mais estudados. O mapeamento de experimentos científicos sobre as modificações do feedback auditivo para o controle motor da voz possibilita examinar a literatura existente sobre o fenômeno e pode contribuir para o treinamento ou terapias da voz. Objetivo Mapear os experimentos e resultados das pesquisas com manipulação do feedback auditivo para o controle motor da voz de indivíduos adultos. Método Revisão de escopo seguindo o Checklist Preferred Reporting Items for Systematic reviews and Meta-Analyses extension (PRISMA-ScR) para responder à pergunta: “Quais os métodos de investigação e principais achados das pesquisas sobre a manipulação do feedback auditivo no automonitoramento da voz de indivíduos adultos?”. O protocolo de busca foi baseado na estratégia mnemônica População, Conceito e Contexto (PCC). A população são os indivíduos adultos; o conceito é a manipulação do feedback auditivo e o contexto é o controle motor da voz. Os artigos foram pesquisados nas bases de dados: BVS/ Biblioteca Virtual em Saúde, MEDLINE/Medical Literature Analysis and Retrieval Sistem on-line, COCHRANE, CINAHL/Cumulative Index to Nursing and Allied Health Literature, SCOPUS e WEB OF SCIENCE. Resultados Foram encontrados 60 artigos, sendo 19 da temática do Efeito Lombard, 25 do efeito Pitch-shift-reflex, 12 do efeito Sidetone e quatro sobre o efeito Sidetone/Lombard. Os estudos são concordantes que a inserção de um ruído que mascara o feedback auditivo provoca um aumento na intensidade de fala do indivíduo e que a amplificação do feedback auditivo promove a redução do nível de pressão sonora na produção da voz. Observa-se uma resposta reflexa à mudança de tom no feedback auditivo, porém, com características individuais em cada estudo. Conclusão O material e método dos experimentos são distintos, não há padronizações nas tarefas, as amostras são variadas, muitas vezes reduzidas. A diversidade metodológica dificulta a generalização dos resultados. Os principais achados das pesquisas a respeito o feedback auditivo sobre o controle motor da voz confirmam que, na supressão do feedback auditivo, o indivíduo tende a aumentar a intensidade da voz. Na amplificação do feedback auditivo, o indivíduo diminui a intensidade e tem maior controle sobre a frequência fundamental e, nas manipulações da frequência, o indivíduo tende a corrigir a manipulação. Os poucos estudos com sujeitos disfônicos mostram que eles se comportam diferentemente dos não disfônicos.
Multi-professional screening instrument for risk of broncho-aspiration in a hospital environment for the elderly population: validity evidence based on response processes
Authors: Miquilussi Paloma Alves , Santos Rosane Sampaio , Massi Giselle Aparecida de Athayde
Published: December 2023

ABSTRACT Purpose The objective of this study was to validate the Multiprofessional Screening Instrument for Broncho-aspiration Risk in Hospital Environment, which is aimed at the elderly population, based on response processes. Methods Judges applied the instrument to different patients and randomly selected. After the application, the judges were interviewed so that it was possible to verify their impression regarding the relevance of the items about their interpretation of the written content, as well as grammatical and semantic issues. Suggestions for adding alternative questions and answers were considered, as well as proposals for adapting the questions that made up the instrument. Non-verbal reactions, such as facial expressions that suggested doubts or hesitations, by the judges concerning the instrument were also analyzed. Results The agreement of the judges concerning each item of the device was calculated by the Content Validity Index (CVI) and by the Intraclass Correlation Coefficient (ICC), and their results showed a high level of agreement. Through the suggestions of the judges, a new version of the Multi-professional Screening Instrument for the Risk of Broncho-aspiration in a Hospital Environment in the Elderly was elaborated. Conclusion The results obtained showed that the validity of the Multi-professional Instrument for Screening the Risk of Broncho-aspiration in the Hospital Environment with the elderly population, based on the response processes, was achieved and makes it a promising device to assist professionals in hospital care for the elderly.