bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of Hardware and Energy Efficient Approximate Multiplier Architectures Using 4-2 Compressor for Images
Authors: C Hema , G Shravani , Sivaphaneendra P , . Sinchana , L Soundarya
Published: April 2023

Abstract: Approximate computing is tentatively applied in some digital signal processing applications which have an inherent tolerance for erroneous computing results. The approximate arithmetic blocks are utilized in them to improve the electrical performance of these circuits. Multiplier is one of the fundamental units in computer arithmetic blocks. Moreover, the 4-2 compressors are widely employed in the parallel multipliers to accelerate the compression process of partial products. In this brief, three novel approximate 4-2 compressors are proposed and utilized in 8-bit multipliers. Meanwhile, an error-correcting module (ECM) is presented to promote the error performance of approximate multiplier with the proposed 4-2 compressors. In this brief, the number of the approximate 4-2 compressor’s outputs is innovatively reduced to one, which brings further improvements in the energy-efficiency. This Design is implemented using Verilog HDL and simulated by Modelsim 6.4 c and synthesized by Xilinx tool.
Cattle Disease Prediction Using Artificial Intelligence
Authors: Rao Mrs. Anitha , H R Monika , B C Rakshitha , Thaseen Seham
Published: April 2023

Abstract: In today’s world identifying cattle disease and providing proper treatments is a challenging task in the current medical sector. As it is difficult to identify thecattle disease in real time, we require a method topredict cattle disease and related patterns. There are so many research works on this topic. Most of the researchworks just presented the idea of cattle disease prediction. There are many works where implementation is done and many papers predicts cattle disease using efficient data science algorithms. Research works where implementation is done uses PYTHON language or R language as programming language for cattle disease prediction. As PYTHON language and R language supports all ready libraries to process training datasets and to predict cattle disease. Many papers use training datasets from www.kaggle.com, www.dataworld.com etc.Research works uses efficient algorithms for prediction, algorithms such as Naive Bayes algorithm, KNNclassifier, SVM classifier, Decision Tree classifier, Random Forest algorithm etc. Most of the papers got very good results of using these algorithms. So many works on this cattle disease and pattern prediction is done using data science techniques.
COVID-19 Future Forecasting System
Authors: P Sukumar , N Sanjaikumar , M Ranjani , G Sandhiya , R Sathish
Published: April 2023

Abstract: Humanity is in danger as a result of COVID-19’s global spread. Due to the illness’s high infectivity and transmissibility, some of the most potent economies in the world are taxed. The capacity of algorithms using expert systems to predict the number of upcoming COVID-19 patients who would contract the disease, which is now thought to pose a threat to humanity. In this study, COVID-19 risk factors were predicted using four traditional predictive models, including the minimal absolute contraction and operator for selection (LR, LASSO, SVM, ES, and LSTM). Each model offers projections for the total of new injections, the total of fatalities, and the total of recoveries. However, it is unable to forecast patients’ precise outcomes. The proposed method, which addresses the issue, and examines the impact of predictive measures like social exclusion and lockouts on the spread of COVID-19, predicts the total of COVID-19 instances in the future 30 days.
Fabrication of Electromagnetic Damper
Authors: Sawant Sahil
Published: April 2023

Abstract: This research study investigates the development of an electromagnetic suspension system for application in highspeed transportation. Using magnetic fields, the technology is intended to elevate and stabilize a vehicle. The construction process and materials utilized to create the suspension system are described in the publication. Testing and evaluating the system's performance, such as its capacity to retain stability and levitation under varying speeds and loads, are part of the research. The research also investigates the effects of changing electromagnetic field parameters on system performance. The study's findings indicate that electromagnetic suspension systems are a promising technology for high-speed transportation, with applications in maglev trains and other comparable vehicles
Perspectivas del cultivo de la saya (Amoreuxia spp.) en el noroeste de México como nuevo producto agronómico.
Authors: Celaya Michel Hernán , Ruelas Islas Jesús del Rosario , Hinojo Hinojo César , Celaya Rosas Maryela , Barrera Silva Miguel Ángel
Published: April 2023

En el pasado los pobladores del noroeste de México se beneficiaron de la planta saya (varias especies del género Amoreuxia), aprovechándola tanto con fines alimenticios como medicinales, luego los colonizadores europeos la aprovecharon como alimento ante hambrunas. Actualmente algunas de estas especies presentan disminución en sus poblaciones, por lo cual han sido consideradas en categorías de riesgo de la NOM 059 de la Secretaría del Medio Ambiente y Recursos Naturales en el año 2010. Esfuerzos recientes han aportado conocimiento sobre formas de multiplicación de la planta bajo condiciones agrícolas. En este trabajo se evaluó el cultivo de saya (A. palmatifida) durante dos años consecutivos, para comparar la productividad del primer año de plantas obtenidas de germinación directa de semillas en condiciones agrícolas, con la productividad del segundo año a partir del rebrote las raíces tuberosas. Se encontró una mayor productividad de las plantas en el segundo año de evaluación (p < 0.0001), tanto en crecimiento de la planta, producción de semillas y peso de las raíces tuberosas. El futuro impacto social de algunas especies del género Amoreuxia puede ser muy positivo aplicando las técnicas de multiplicación de esta especie, descritas en este trabajo, para recuperar esta planta en los terrenos de agostadero del noroeste de México e incluso para generar nuevos cultivos.
The Relationship between Team Learning Activities, Collaborative Self-Efficacy, and Learning Performance in Face-to-face Classes
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, GO JEONGLEE
Published: April 2023

Objectives The purpose of this study was to analyze the effects of team learning activities and cooperative self-efficacy perceived by pre-service teachers on learning performance and to empirically verify the mediating effects of cooperative self-efficacy in the relationship between team learning activities and learning performance.
Methods For this purpose, 324 pre-service teachers attending the National University of Education in G city, Gyeongsangnam-do were selected as research subjects. The team learning activities were selected as independent variables, cooperative self-efficacy as mediator variables, learning flow and satisfaction as dependent variables. The collected data were analyzed by using SPSS program to verify reliability, correlation and multiple regression analysis.
Results There was a significant positive relationship between team learning activities, cooperative self-efficacy, and learning performance perceived by the preliminary teachers, and team learning activities and cooperative self-efficacy had a positive effect on learning performance. In addition, cooperative self-efficacy in the relationship between team learning activities and learning performance has a significant effect as a partial mediating variable.
Conclusions In order to improve the quality of university classes, various measures should be considered to improve learning performance. In order for learners to feel immersed in learning and satisfied with the class, the method of the class should strengthen team learning activities in individual learning, and learners should actively promote cooperative self-efficacy that can share and evaluate team opinions in team learning activities.
Exploring the leadership styles and meaning of 5-year-old children in peer play
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Sung suk
Published: April 2023

Objectives The present study describes the leadership styles of 5-year-old children in play situation. Also, this study interprets the meaning of these leadership styles.
Methods For the purpose of understanding the leadership style of young children, this study conducted topic oriented ethnographic field work in day care center classroom for 3 month. The data were collected through participant observation in the day care center classroom and interview with teacher and content analysis.
Results Based on the analisis of ethnographic data thus collected, the results showed that the leadership styles of young children in play situation were the Leadership that suggests the beginning and direction of play, Leadership in developing peers, Leadership in Resolving Conflicts in Play, Leadership that directs and controls friends. The meaning that these leadership styles have were there is leadership style that playing to its strengths in a certain situation, effective leader utilize various leadership styles flexibly and every child is leader.
Conclusions These findings should contribute to teacher's understanding of young children' leadership. And they can be used as a reference for planning appropriate ways to structure early childhood educational activity.
The Effect of Self-Directed Learning on Career Adaptability of Adult Learners: Focusing on the Mediating Effect of Self-Efficacy in Career Decision
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Joo Mi Ran , Jung Ki Soo
Published: April 2023

Objectives This study is to verify the mediating effect of career decision self-efficacy in the relationship between the influence of adult learners' self-directed learning on career adaptability.
Methods For this purpose, 413 adult learners were selected as study subjects, and the data were analyzed using the SPSS 25 statistical program. Descriptive statistical analysis was conducted to identify the general characteristics and normality of the collected data, and reliability analysis and exploratory factor analysis were conducted to determine reliability and validity. In addition, a correlation analysis was performed to identify the correlation between major variables, and a regression analysis was conducted to verify the mediating effect of self-efficacy in career decision-making in the relationship between the effects of self-directed learning on career adaptability.
Results First, the cognitive domain, affective domain, and behavioral domain, which are the sub-factors of adult learners' self-directed learning, had a significant effect on career adaptability. Second, the cognitive domain, affective domain, and behavioral domain, which are the sub-factors of adult learners' self-directed learning, showed a statistically significant level in career decision self-efficacy. Third, the verification of the mediating effect of self-efficacy in career decision-making was significant in the relationship between cognitive domain, affective domain, and behavioral domain, which are the sub-factors of adult learners' self-directed learning, on career adaptability.
Conclusions Based on this, self-directed learning and career decision-making self-efficacy should be promoted in order to increase career adaptability of adult learners. Through this, it is intended to provide implications and basic data for lifelong education of adult learners.
Development of Entrepreneurship Education Program for Elementary School Students' Real Life Problem Solving Competency Development and Implementation Effect
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Moon Youngjin , Park Suhong , Chae Da Young , Kang Ju Hyun
Published: April 2023

Objectives This study was to develop an entrepreneurship education program for the development of real-life problem-solving competences in elementary school, and to investigate the effects after conducting classes.
Methods For the development of an entrepreneurship education program, a draft was devised through literature research and learner's demand analysis. And the final draft was developed through expert evaluation of the draft. Introspection data were collected during the course of class in this program. After class, 25 participating students were divided into 6 groups, and focus group interviews (FGI) were conducted. The data collected in this way were analyzed according to the content analysis method to find out the effectiveness of the educational program.
Results Through the classes of the entrepreneurship education program, the students went through the 16 class hour. In this process, students were able to develop application and analysis of knowledge, communication skills, creativity, leadership and execution skills. In addition, in the process of problem-solving, students were able to obtain positive effects such as challenging spirit for difficulties, positive self-awareness, and self-efficacy.
Conclusions The point of entrepreneurship education program is to find empathic problems in real life, create solutions, and put them into practice. Entrepreneurship education program is useful as an educational method to develop competencies necessary for the future society. Entrepreneurship education is to discover and define problems from unstructured situations in real life spaces, and to directly practice solutions created while interacting through team activities. Entrepreneurship education is an educational method that internalizes problem-solving capabilities and is an essential method for fostering future social capabilities.
The Moral Educational Significance of a Study on the Development of a Self-Esteem Improvement Program for Elementary School Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Ayeong , Kim Sang-In
Published: April 2023

Objectives The purpose of this study is to develop and apply a self-esteem improvement program for elementary school students, and to explore its moral educational significance.
Methods This study operated a self-esteem improvement program for 226 students in the 3rd to 5th grades of elementary school and derived its significance through t-test. In addition, it was intended to clarify the significance of moral education through this.
Results The self-esteem improvement program for 3rd to 5th graders generally produced significant results. However, more research is needed to ensure that self-esteem leads to respect for others. In order for the self- esteem improvement program to be significantly operated, it is essential to secure a stable and continuous number of classes. In addition, an authorized curriculum is needed to improve self-esteem. As moral subjects are the backbone of students' personality education and democratic citizenship education, it is necessary to study education to improve self-reliance and field-oriented education methods that can be expanded to respect others.
Conclusions The self-esteem improvement program for elementary school students conducted through this study generally provided meaningful experiences to students. In order for such a significant self-esteem program to be generalized to the school field, a stable curriculum based on the number of classes is needed, and it is suggested to solve this problem through moral subjects that are the center of students' personality education and democratic citizenship education.
Comparison and Analysis of Middle School Trigonometry Textbook Tasks and Teacher Design Tasks: From the Perspective of Mathematical Modelling
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Park Eun young , Kwon Oh Nam
Published: April 2023

Objectives In this study, the triangulation task actually used in the middle school class is analyzed from the perspective of the mathematical modelling tasks.
Methods Various triangulation tasks were collected from middle school trigonometry textbooks and activity sheets produced and used by teachers, and classified based on whether connectivity and openness, which are the core characteristics of mathematical modelling tasks, were met, and cognitive activities required. Then, mathematical modelling tasks is selected from among the teacher-designed tasks, and the activities of the tasks and the interviews of the teachers in each mathematical modelling tasks are interpreted according to the mathematical modelling cycle.
Results Teacher-designed tasks were found to have higher connectivity and openness than textbook tasks, including familiar material, offering practical and specific data, or insufficient data to solve the task. On the other hand, all tasks selected as mathematical modelling tasks among teacher-designed tasks emphasized simplifying, mathematising, and working mathematically, but relatively put less emphasis on understanding, interpretation, and validation. In particular, the process after working mathematically turned out to be limited to the extent of attaching units to the mathematical results, rounding it, or reviewing whether the calculation of the result were correct. In addition, all tasks used only the concept of tangent and did not require other concepts of trigonometric ratio.
Conclusions Several examples of triangulation tasks can be found in Korean and foreign mathematical modelling studies. As such, mathematical modelling teaching/learning method is useful to teach trigonometry due to its usefulness in real life. According to the results of this paper, teachers want to design assignments rich in connectivity and openness so that students can recognize the usefulness of the concept of trigonometric ratio. Furthermore, if the various cognitive activities in the mathematical modelling cycle are evenly included, and various trigonometry tasks including various models are designed, it would lead more meaningful teaching and learning of mathematical modelling as well as trigonometry and ultimately it would help students improve problem-solving skills.
Functional connectivity of brain structures in patients with anorexia nervosa based on resting state fMRI: prospective study
Authors: Grebenshchikova R. V. , Ananyeva N. I. , Pichikov A. A. , Iskhakov D. N. , Lukinа L. V.
Published: April 2023

INTRODUCTION: This paper analyzes local and foreign literature on functional magnetic resonance imaging (fMRI) in patients with anorexia nervosa. Resting state fMRI results of the brain of patients with anorexia nervosa (AN) are presented.

OBJECTIVE: To study functional connectivity in the networks in resting state in patients with AN.

MATERIALS AND METHODS: 43 patients with anorexia nervosa aged 14 to 19 years were examined. The control group consisted of 31 healthy volunteers. The connectivity of the structures involved in the formation of the default mode brain network, frontoparietal and visual networks was analyzed. Statistics: Mathematical and statistical processing was applied in the programming environment of the Python programming language, using the Jupyter-notebook development environment and application modules for statistical analysis Pandas and Numpi. The main tools for statistical analysis of functional MRI were the specialized software package CONN-TOOLBOX.

RESULTS: In the default mode network, a decrease in connectivity between the medial prefrontal cortex and the cluster including the angular gyrus and the supramarginal gyrus, and an increase in connectivity between the right lateral parietal cortex and the cluster including the left precentral and postcentral gyrus, were revealed. In the frontoparietal network, significant indicators of a decrease in connectivity between the right lateral prefrontal cortex and three clusters were obtained, including the poles of the frontal lobes, the left superior and middle frontal gyri, and the left lateral occipital cortex. In the visual network, there was a decrease in connectivity between the left lateral visual network and the cluster which includes mainly the lateral parts of the cerebellar hemispheres and its vermis, the right lateral visual network and the cluster which includes mainly the right and left lingual gyrus, cerebellar hemispheres and vermis.

CONCLUSION: Our study showed a disruption of the functional connectivity in patients with AN, leading to visuospatial disorders and, as a result, a change in the complex process of setting goals, planning appropriate steps to these goals, and impaired cognitive control.
Construction, stochastization and computer study of dynamic population models “two competitors - two migration areas”
Authors: Vasilyeva Irina I. , Demidova Anastasia V. , Druzhinina Olga V. , Masina Olga N.
Published: April 2023

When studying deterministic and stochastic population models, the actual problems are the formalization of processes, taking into account new effects caused by the interaction of species, and the development of computer research methods. Computer research methods make it possible to analyze the trajectories of multidimensional population systems. We consider the “two competitors - two migration areas” model, which takes into account intraspecific and interspecific competition in two populations, as well as bidirectional migration of both populations. For this model, we take into account the variability of the reproduction rates of species. A formalized description of the four-dimensional model “two competitors - two migration areas” and its modifications is proposed. Using the implementation of the evolutionary algorithm, a set of parameters is obtained that ensure the coexistence of populations under conditions of competition between two species in the main area, taking into account the migration of these species. Taking into account the obtained set of parameters, a positive stationary state is found. Two-dimensional and three-dimensional projections of phase portraits are constructed. Stochastization of the model “two competitors - two migration areas” is carried out based on the method of self-consistent one-step models constructing. The Fokker-Planck equations are used to describe the structure of the model. A transition to a four-dimensional stochastic differential equation in the Langevin form is performed. To carry out numerical experiments, a specialized software package is used to construct and study stochastic models, and a computer program based on differential evolution is developed. Algorithms for generating trajectories of the Wiener process and multipoint distributions and modifications of the Runge-Kutta method are used. In the deterministic and stochastic cases, the dynamics of the trajectories of populationmigration systems is studied. A comparative analysis of deterministic and stochastic models is carried out. The results can be used in modeling of different classes of dynamic systems.
Causality relationship between foreign direct investments and economic improvement for developing economies: Russia case study
Authors: Brou Kouame A. , Smirnov Ivan V.
Published: April 2023

Foreign direct investment (FDI) can have a significant impact on economic development in developing economies like Russia. FDI can bring in capital, technology, and management expertise that can stimulate economic growth, increase employment, and improve productivity. In the case of Russia, FDI has played a vital role in the country’s economic development. A study conducted by the World Bank in 2019 found that FDI inflows have contributed significantly to Russia’s economic growth and led to increased productivity, employment, and exports. The article analyzes the relationship between foreign direct investment and economic growth in Russia using ARDL cointegration and Toda-Yamamoto causality analysis test. The results reveal that there is no causality relation between GDP growth and foreign direct investment inflow in Russia. Overall, foreign direct investment effectively contributes to economic growth in Russia in the short term and not really in the long run.
Julia language features for processing statistical data
Authors: Gevorkyan Migran N. , Korolkova Anna V. , Kulyabov Dmitry S.
Published: April 2023

The Julia programming language is a specialized language for scientific computing. It is relatively new, so most of the libraries for it are in the active development stage. In this article, the authors consider the possibilities of the language in the field of mathematical statistics. Special emphasis is placed on the technical component, in particular, the process of installing and configuring the software environment is described in detail. Since users of the Julia language are often not professional programmers, technical issues in setting up the software environment can cause difficulties that prevent them from quickly mastering the basic features of the language. The article also describes some features of Julia that distinguish it from other popular languages used for scientific computing. The third part of the article provides an overview of the two main libraries for mathematical statistics. The emphasis is again on the technical side in order to give the reader an idea of the general possibilities of the language in the field of mathematical statistics.
Studying the mechanism of electric explosion of metal conductors
Authors: Kravchenko Nikolay Yu. , Kovtunov Sergey S.
Published: April 2023

The article gives a description of the history of the development of research of electric explosion of metal conductors, the authors offer a modern view on the physics of the process of electric explosion. The result of such an explosion can be, in particular, the production of nanopowders, which today have found the widest application in industry, agriculture, medicine, and so on.
Formation of adaptive strategies of population to combat poverty in the conditions of uncertainty (sociological analysis)
Authors:   The Pacific State University, Shugaeva I.V.
Published: April 2023

The problem of modern Russian society is to accept the position that uncertainty of the socio-economic processes dictates the formation of new social systems and the study of the mechanisms of adaptive strategies of the population, which becomes an integral part of everyday life. For a comfortable existence (adaptation), it is necessary to interact with the subjects of society with the micro and macro environment, which analyzes the indicators of the sustainable state of external and internal factors in the implementation of the goals and further development of individual strategies to combat poverty. The study of various adaptation approaches under conditions of uncertainty is of particular relevance. The purpose of this article was to study different types of adaptive strategies of population to combat poverty in the face of uncertainty, since it is an important resource for the overcoming material difficulties. Based on the study of publications of the Russian and foreign sociologists and the analysis of official statistics, the article shows the main trends in the fight against poverty and the choice of adaptation strategies based on the available resources of the population of the Khabarovsk territory. Particular attention in the article is given to the subjective assessments of respondents about their financial situation. Comparative assessment based on the material resources of population revealed important directions in the adoption of active adaptation strategies in the fight against poverty and showed that, firstly, dissemination of these strategies in the society leads to improvement in the material well-being and possibility of the further social growth. Secondly, low level of adaptation and use of the more passive strategies in the face of uncertainty will reduce the level of well-being of the population. Adaptation in the modern conditions allows show the most flexible forms of behavioral strategy, subject to the active life position. The use of several types of strategies (passive and active) makes it possible to successfully overcome the state of poverty in the face of uncertainty, as well as to increase the level of material well-being.
Economy of the Far East in 2022: analytical results
Authors:   The Federal Autonomous Institution «the Eastern Center for State Planning», Latysheva N. E. , Nazarenko O. A. ,   The Federal Autonomous Institution «the Eastern Center for State Planning», Ageshina E. Yu. ,   The Federal Autonomous Institution «the Eastern Center for State Planning»
Published: April 2023

The This article analyzed economic development of the Far-Eastern federal district in 2022 in the context of the regions and key activities on the basis of statistical data , information from the executive authorities of the subjects of the Far-Eastern federal district and expert assessments. Reasons for the dynamics of industrial production, investment in the fixed assets, construction, agriculture, and the consumer sector are given.
De regreso a la caverna. La técnica y la violencia mimética en el cibersexo
Authors: Ballén Rodríguez Juan Sebastián
Published: April 2023

El siguiente artículo propone un acercamiento filosófico al fenómeno del cibersexo en diálogo con la sociología, la teoría mimética y el derecho. Su alcance es el de lograr una interpretación interdisciplinar al objeto de estudio planteado, pensando en sus aplicaciones para el estudio de la violencia de género en el mundo de la virtualidad. La metodología combina elementos de la hermenéutica textual y un análisis situado que corresponde propiamente al fenómeno de la cibersexualidad. Uno de los resultados más destacados es el descubrimiento que la dinámica tecnológica y económica del modelaje webcam reduce la vida humana a un mecanismo sacrificial, donde el género femenino es expuesto a una interminable cadena de violencias simbólicas, sistémicas y subjetivas. Las principales conclusiones de este análisis dialógico al problema en cuestión se pueden identificar del siguiente modo: 1. La cibersexualidad funge a modo de un dispositivo tecnológico donde se producen ficciones somáticas generadoras de entretenimiento, donde se alternan el placer y la violencia; 2. El modelaje webcam reproduce una dinámica sacrificial que termina por construir un tipo de violencia de género; 3. La técnica y el simulacro son instancias que se combinan en el mundo del entretenimiento cibersexual, de tal modo que las nuevas realidades humanas que dominan en el mundo de la virtualidad plantean desafíos éticos, jurídicos y políticos, los cuales nos encaminan hacia un feliz regreso a la caverna.
EFFECT OF PLAN SHAPE ON HYDRAULIC CHARACTERISTICS OF LABYRINTH WEIRS
Authors: Tanga Arody , Ishak Muh. Galib , Arafat Yassir
Published: April 2023

Labyrinth weirs have a longer crest length compared to linear weirs to increase the discharge capacity for a given water head. Generally, the plan shape of labyrinth weirs is triangular, trapezoidal, and rectangular. In this regard, several studies have been published regarding determining the hydraulic characteristics of labyrinth weirs. However, the effect of changing the plan shape if other parameters such as the same length and height have not been addressed in the current literature. To fill this gap, this study aims to compare the hydraulic characteristics of flow over triangular, trapezoidal, and rectangular labyrinth weirs with the same length of the crest i.e. 230 cm length. Experiments study were conducted in a flume with a length of 16 m and a width of 95 cm. Three experimental models in this study were used. The results of this study indicated that changing the plan shape from trapezoidal to triangular increased the discharge coefficient (Cd) by about 38,0% on average. Furthermore, changing rectangular to triangular increased the Cd by about 64,5% on average. Thus, it can be concluded that the triangular model was the most efficient hydraulically compared to the others while the rectangular model was the least efficient.
ANALISIS GAYA GESER DASAR DAN SIMPANGAN STRUKTUR GEDUNG UTAMA FAKULTAS TEKNIK UNIVERSITAS NEGERI GORONTALO BERDASARKAN SNI
Authors: Ekatama Yudistira , Nur Kasmat Saleh , Gani Mirzan
Published: April 2023

Gedung utama Fakultas Teknik Universitas Negeri Gorontalo di Kabupaten Bone Bolango dibangun pada tahun 2017 berdasarkan SNI 1726:2012. Adanya perkembangan ilmu pengetahuan dan teknologi, pada tahun 2019 diterbitkan SNI 1726:2019 menggantikan SNI 1726:2012, maka dilakukan penelitian untuk melihat pengaruh perubahan SNI 1726:2012 menjadi SNI 1726:2019 terhadap nilai gaya geser dasar (V) dan simpangan antar lantai (Δ) gedung utama Fakultas Teknik Universitas Negeri Gorontalo. Penelitian ini menggunakan data yang diperoleh dari PIU IDB UNG (Project Implementation Unit Islamic Development Bank Universitas Negeri Gorontalo) berupa gambar perencanaan bangunan, data umum mutu bahan yang dipakai, dan data tanah. Prosedur analisis menggunakan bantuan program ETABS versi 17.0.1. Hasil analisis nilai gaya geser seismik statik (VStat) dan gaya geser seismik dinamik (VRS) yang terjadi mengalami penurunan, nilai gaya geser seismik statik (VStat) untuk arah X dan Y mengalami penurunan 18,8% dan untuk nilai gaya geser seismik dinamik (VRS) arah X mengalami penurunan 4,74% dan arah Y mengalami penurunan 5,35%. Adapun hasil analisis nilai simpangan antar lantai (Δ) di setiap tingkat tidak melewati batas simpangan izin yaitu 58,65 mm. Nilai rata-rata simpangan antar lantai (Δ) dari setiap tingkat untuk arah X mengalami penurunan 4,77% dan untuk arah Y mengalami penurunan 5,37%.
Economic evaluation of cost and outcomes of healthcare services: A guide for optimal healthcare decision-making
Authors: Idris Abubakar , Nwoko Michael , Umar Salisu Shehu , Iyoha Emhenya A. , Maduako Kenneth T.
Published: April 2023

This study evaluated the cost and outcomes of healthcare services in some African countries with a particular focus on the sub-Saharan African (SSA) regions. It carried out analyses of fixed, random, and dynamic effect of lagged cost of healthcare on health outcomes. To achieve the study’s objective, cross-sectional data from eight (8) African countries were obtained from secondary sources. Panel regression econometric techniques and panel generalised moment/dynamic (PGMM/D) methods were used to determine the lagged effects among the study variables. This study identified the pooled, fixed, and random effects of healthcare costs on health outcomes. It was statistically significant at a 5 percent level. This study documented a positive relationship between health outcomes needs and healthcare costs. The behaviour exhibited by the variables was symmetrical, as revealed by the mean and the standard deviation of the descriptive analysis estimates. The findings of the regression analysis confirmed the peculiarity of the health outcomes and healthcare cost positions among the selected countries. The health outcomes estimate constituted strong drivers of healthcare costs. Therefore, in line with the findings of Healthcare Value Hub (2018), optimal interventions to address technological inadequacy and inefficient system performance to achieve quality health outcomes are recommended
Incidence and Risk Factors of Primary Postpartum Hemorrhage after Vaginal Delivery in Kasr Al Ainy University Hospital: a Cross-sectional Study
Authors: Genina Hanya , Mazen Ahmed M. , Rizk Mohamed M. , Kamal Salma , Shawky Omar , Hisham Abdullah , Genina Amr , Sherif Nadine Alaa
Published: April 2023

Background: Approximately 15% of all pregnant women (about 20 million
women) suffer from acute severe obstetric complications
, and the first 24 hours postpartum and the first
week after labor represent the main periods with the highest chances of
mortality. The most evident complication of which is hemorrhage; solely
accounting for 27% of all maternal deaths that occur worldwide
, and it being postpartum accounts for 73% of
all the hemorrhage cases. . Primary Post-partum
hemorrhage is formally defined as the loss of at least 500 ml of blood
after a vaginal birth or the loss of at least 1,000 ml of blood after a
cesarean section within 24 hours of delivery. Aim:
In light of this, this cross-sectional study aims to evaluate the
incidence and determine risk factors of PPH after vaginal delivery in
Kasr Alainy University Hospital in Cairo, Egypt. Methodology: The study
is a multivariate cross-sectional study. Single population proportion
formula was used to determine the sample size in accordance with
inclusion and exclusion criteria. Data was collected via assisted
questionnaires and results were statistically interpreted with a
confidence interval of 95% to gather the odds ratio of different
statistically significant risk factors of PPH. Results: PPH incidence in
Kasr AlAiny in the period of our study was 8.1%. Atonic factors were
implicated in 67% of all PPH after vaginal delivery in the study. Most
evident risk factors were prolonged labor (odds ratio= 5.1), then
history of previous PPH (odds ratio= 4.25), followed by hypertension
(odds ratio 2.53) and lastly advanced age ⩾35 years (odds ratio= 2.29)
Conclusion: Our research concluded that most cases of PPH were mainly of
atonic causes and primarily with prolonged labor being the most evident
risk factor.
Myricanol represses renal fibrosis by activating tubular TFAM-ZNRF1/LCN2 pathway to improve mitochondrial bioenergetics
Authors: Zheng Ming , You Jun , Hu Zheng , Gao Bao , Cui Wei , Yao Wan , Jiang Qiao , Su Feng , Sun Xue , La Lei
Published: April 2023

Background: Mitochondrial biology destroy lead to renal fibrosis.
Targeted therapy of ferroptosis may play an important role in protecting
renal functions. Myricanol has been shown ameliorate muscle dysfunction
by increasing mitochondrial biogenesis. However, few studies on
myricanol in renal fibrosis has been performed. Purpose: We explore that
myricanol can relieve renal fibrosis by improving mitochondrial
bioenergy and inhibiting ferroptosis. Approach: Renal ferroptosis model
was established using bilateral ischemia reperfusion (BIRI), which was
used to study association between ferroptosis and renal fibrosis.
Ferroptosis associated protein including zinc and ring finger 1 (ZNRF1)
and iron transport-related protein lipocalin-2 (LCN2) interactions were
verified by co-immunoprecipitation. Two concentrations of myricanol,
namely 0.5 mg/kg and 2 mg/kg, were included to treat unilateral ureteral
obstruction (UUO) induced mouse model of chronic kidney disease (CKD).
Results: We have shown that myricanol could inhibits ferroptosis,
maintains mitochondrial integrity and renal function. Mitochondrial copy
number were decreased in CKD patient blood sample. We further confirmed
that primary renal tubular cells with TFAM deficiency were more prone to
ferroptosis. Transcriptional sequencing showed the level of ZNRF1 having
significant differences between TFAM-/- and TFAM+/+ group. TFAM
deficiency decrease the interaction between LCN2 and ZNRF1. Treatment
with myricanol reduced renal fibrosis by regulating TFAM expression and
ferroptosis. Conclusions: Our study firstly demonstrated that myricanol
strengthen tubular bioenergetic capacity depended on TFAM increasing the
interaction between LCN2 and ZNRF1 to inhibit ferroptosis and suggested
that myricanol might be promising drugs for treating renal fibrosis.
COVID-19 disease in children and adolescents following hematopoietic stem cell transplantation: A report from the Turkish Pediatric Bone Marrow Transplantation Study Group
Authors: BOZKURT CEYHUN , Hazar Volkan , Malbora Baris , Küpesiz Alphan , Aygüneş Utku , Fısgın Tunc , Karakükçü Musa , Kuskonmaz Baris , Kilic Suar Çakı , Bayırlı Derya , Bilir Özlem Arman , Yalcin Koray , Gözmen Salih , Uygun Vedat , Elli Murat , Sarbay Hakan , Küpesiz Funda , Şaşmaz Hatice İlgen , Aksoy Basak , Yılmaz Ebru , Okur Fatma , Tekkeşin Funda , Yenigürbüz Fatma Demir , Ozek Gülcihan , Atay Avni , Bozkaya İkbal Ok , Çelen Suna , Ozturkmen Seda , Gunes Adalet , Gursel Orhan , Guler Elif , Özcan Alper , Uçkan Duygu , Aydogdu Selime , Özbek Namık Yaşar , Karasu Gulsun , Sezgin Gulay , Dogru Omer , Albayrak Davut , Öztürk Gülyüz , Aksoylar Serap , Daloglu Hayriye , Al Işık Odaman , Evim Melike Sezgin , Akbayram Sinan , Öncül Yurday , Zengin Emine , Albayrak Canan , Cetin Timur , Kar Yeter Düzenli , Çakmaklı Hasan Fatih , Tüfekçi Özlem , Toret Ersin , Antmen Bulent
Published: April 2023

Background: Data on the outcome and risk factors of pediatric
patients with SARS-CoV-2 infection (COVID-19) following hematopoietic
stem cell transplantation (HSCT) are limited. Objectives: We
aimed to describe risk factors for a severe course and mortality.
Method: In this nationwide study, data were collected
retrospectively from 28 transplant centers. Results: One
hundred ninety-six children [(63.8% male; median age 8.75 (IQR,
4.86-14.30)] who received allogeneic (n: 184, 93.9%) or autologous
(n: 12, 6.1%) HSCT were included. The median time from HSCT to
SARS-CoV-2 infection was 207.5 days (IQR, 110.2-207.5). The most common
clinical manifestation was fever (58.2%), followed by cough (33.7%);
43 cases (21.9%) were asymptomatic. Lower respiratory tract disease
(LRTD) and multisystem inflammatory syndrome in children (MIS-C)
developed in 58 (29.6%) and 8 (4.1%) patients, respectively.
Twenty-six patients (13.3%) required ICU admission. Nine patients died
at a median of 17 days (min-max 1-33) after COVID-19 diagnosis, 6 of
whom died due to the disease, with a COVID-19 lethality rate of 3.1%.
The 6-week overall survival was 95.4% (95% CI 92.5-98.3). Multivariate
analysis found that HSCT with a mismatched donor (OR, 8.98, p: 0.039)
and LRTD (OR, 61.55, p: 0.001) were independent risk factors for ICU
admission; MIS-C (OR, 9.55, p: 0.044) and lymphopenia (OR, 4.01, p:
0.030) at diagnosis were risk factors for mortality.
Conclusion: Overall mortality was lower in children than in
adult counterparts, and HSCT with a mismatched donor, lymphopenia, LRTD,
MIS-C and ICU admission were important risk factors for adverse
outcomes.
The lung ultrasound in children with SARS-COV 2 infection: a national multicenter prospective study
Authors: Supino Maria , Buonsenso Danilo , Agostiniani Rino , Gori Laura , Tipo Vincenzo , Morello Rosa , Delmonaco Angelo Giovanni , Falsaperla Raffaele , Biagi Carlotta , Cazzato Salvatore , Villani Alberto , Musolino Anna Maria , Scateni Simona , Ferro Valentina , Scialanga Barbara , Mesturino Alessia , Boccuzzi Elena , D'Anna Carolina , Romagnoli Vittorio , Marino Silvia , Puxeddu Roberta , Martelli Gaia , Gagliardo Thaililja , Murciano Manuel , Pellizzoni Federica
Published: April 2023

Covid-19 causedhospitalizations, severe disease and deaths in any age,
including in the youngest children. The aim of this multicenter national
study is to characterize the clinical and the prognostic role of lung
ultrasound (LUS) in children with Covid-19. We enrolled children between
1 month and 18 years of age diagnosed with SARS-CoV2 infection and
whounderwenta lung ultrasound within 6 hours from firstmedical
evaluation. A total of 213 children were enrolled, 51.6%were male,
median age was2 years and 5 months (IQR 4mm- 11 yearsand4 months).One
hundred and fortyeight (69.4%) children were admitted in hospital, 9
(6.1%) in pediatric intensive care unit.We found an inverse correlation
between the LUS score and the oxygen saturationatthe clinical evaluation
(r = −0.16; p = 0.019). Moreover, LUS scores were significantly higher
in patients requiring oxygen supplementation (8 (IQR 3 - 19) vs 2 (IQR 0
- 4); p= 0.001). Among LUS pathological findings, irregular pleural
line, sub-pleural consolidations and pleural effusions were
significantly more frequentin patients whoneeded oxygen supplementation
(p = 0.007; p = 0.006 andp = 0.001, respectively). This multicentric
study confirmed that LUS is able to detect Covid-19 low respiratory
tract involvement, which is characterized by pleural line
irregularities, vertical artifacts and subpleural consolidations.
Notably, children with higher LUS score have an higher risk of
hospitalization or need for oxygen supplementation, supporting LUS as a
valid and safe point-of-care first level tool for the clinical
evaluation of children with Covid-19.
A Panoramic Analysis of Sports and Healthy Aging Research in China and Abroad: Knowledge Framework, Hotspot and Evolutionary Path
Authors: LI Xiaoyu
Published: April 2023

Objective: This study aims to conduct a panoramic analysis of
foreign and Chinese research on sports and healthy aging, and to
construct a research knowledge framework based on the mechanism of the
role of sports on healthy aging and the value creation of sports on
healthy aging as a system. Methods: We use the literature
included in the Web of Science core collection and CNKI database was
used as the study sample, and bibliometric analysis was performed on the
literature sample using analysis software such Bibexcel and SPSS.
Results: There are links and differences between China and
foreign countries in terms of the mechanisms and value creation of sport
for healthy aging. While Chinese and foreign studies have focused on
three aspects of physical activity behavior, health interventions for
older persons, and exercise guidelines for older persons, foreign
studies have focused more on individual aspects of older persons, while
Chinese studies have focused more on the development of policies for
older persons. Conclusions: Based on the national conditions of
China, the study proposes the research idea of sports and healthy aging
as an important issue to cope with population aging, as a social system
project of universal health care, and as a reflection of individual
quality of life. This will provide very important practical guidelines
for geriatric care.
The correlation between four adherence measurements methods in patients with rheumatoid arthritis using methotrexate
Authors: Hebing Renske , Elhendy Nada , Geel Eva , Heuckelum Milou , Nurmohamed Michael , Bemt Bart van den
Published: April 2023

Objective Methotrexate (MTX) is the cornerstone in the treatment of
rheumatoid arthritis (RA) patients. However, adherence to MTX therapy is
not optimal, and instruments to assess medication non-adherence are
warranted. To date there is no consensus on the best method to determine
adherence to MTX. The aim of this study was to assess the correlation
between adherence assessed with a Medication Event Monitoring System
(MEMS) versus pill count, MTX-polyglutamate (PG) concentration and
Compliance-Questionnaire-Rheumatology (CQR) in patients with established
RA. Second, the correlations between these methods and the Disease
Activity Scores of 28 joints (DAS28) were examined. Methods Adult RA
patients currently treated with MTX were included. Multivariable linear
and logistic regression were used, with adherence assessed with MEMS as
dependent variable versus pill count, MTX-PG concentrations, CQR as
independent variables, and DAS28 versus each of the four adherence
measurements. Covariates were included, such as comedication, age and
use of corticosteroids. Results 190 consecutive RA patients were
included. Pill count was correlated with adherence assessed with MEMS
(linear regression, β = .690, p = <.001), whereas CQR and
MTX-PGs were not. Logistic regression confirmed the correlation between
dichotomized adherence and pill count only (β = 5.64, p=
<.001). No other correlations were found, neither for all
adherence outcomes and DAS28. Conclusion Measuring adherence with MEMS
is correlated with pill count, whereas other methods were not correlated
with MEMS, nor with DAS28. Pill count can be used to estimate adherence
to MTX therapy, in case MEMS is not achievable.