bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular Pathways Regulating Circadian Rhythm and Associated Diseases
Authors: Ding Min , Zhou Hang , Li Yu-Mei , Zheng Yun-Wen
Published: May 2024

Circadian rhythms, the natural cycles of physical, mental, and behavioral changes that follow a roughly 24-hour cycle, are known to have a profound effect on the human body. Light plays an important role in the regulation of circadian rhythm in human body. When light from the outside enters the eyes, cones, rods, and specialized retinal ganglion cells receive the light signal and transmit it to the suprachiasmatic nucleus of the hypothalamus. The central rhythm oscillator of the suprachiasmatic nucleus regulates the rhythm oscillator of tissues all over the body. Circadian rhythms, the natural cycles of physical, mental, and behavioral changes that follow a roughly 24-hour cycle, are known to have a profound effect on the human body. As the largest organ in the human body, skin plays an important role in the peripheral circadian rhythm regulation system. Like photoreceptor cells in the retina, melanocytes express opsins. Studies show that melanocytes in the skin are also sensitive to light, allowing the skin to “see” light even without the eyes. Upon receiving light signals, melanocytes in the skin release hormones that maintain homeostasis. This process is called “photoneuroendocrinology”, which supports the health effects of light exposure. However, inappropriate light exposure, such as prolonged work in dark environments or exposure to artificial light at night, can disrupt circadian rhythms. Such disruptions are linked to a variety of health issues, emphasizing the need for proper light management in daily life. Conversely, harnessing light’s beneficial effects through phototherapy is gaining attention as an adjunctive treatment modality. Despite these advancements, the field of circadian rhythm research still faces several unresolved issues and emerging challenges. One of the most exciting prospects is the use of the skin’s photosensitivity to treat diseases. This approach could revolutionize how we think about and manage various health conditions, leveraging the skin’s unique ability to respond to light for therapeutic purposes. As research continues to unravel the complexities of circadian rhythms and their impact on health, the potential for innovative treatments and improved wellbeing is immense.
Clinical Implications of Acute Stent Mal-Apposition in the Left Main Coronary Artery
Authors: Wu Xi , Wu Mingxing , Huang Haobo , Wang Lei , Liu Zhe , Cai Jie , Huang He
Published: May 2024

Background: Intravascular ultrasound (IVUS) has been utilized to determine acute stent mal-apposition (ASM) after percutaneous coronary intervention (PCI) in the left main coronary artery (LMCA). However, the clinical consequences of this finding remain uncertain. This research aimed to evaluate the clinical implications of ASM in the LMCA using IVUS. Methods: In this study, 408 patients who underwent successful drug-eluting stent (DES) implantation in the LMCA were evaluated. We analyzed the prevalence and characteristics of ASM and its correlation with clinical outcomes. ASM is characterized by stent struts that are not in immediate proximity to the intimal surface of the vessel wall after initial stent deployment. Results: The observed incidence of LMCA-ASM post-successful PCI was 26.2%, both per patient and per lesion. Lesions with LMCA-ASM had a longer stent diameter, larger stent areas, and larger lumen areas compared to those without LMCA-ASM (4.0 ± 0.5 vs. 3.7 ± 0.4 mm, p < 0.001; 9.8 ± 2.0 vs. 9.0 ± 1.6 mm2, p < 0.001; 12.3 ± 1.9 vs. 10.1 ± 2.1 mm2, p < 0.001, respectively). The mean external elastic membrane (EEM) area (odds ratio (OR): 1.418 [95% confidence interval (CI): 1.295–1.556]; p < 0.001) emerged as an independent predictor of LMCA-ASM. During the observation period, LMCA-ASM did not display any association with device-oriented clinical endpoints (DoCE), which included cardiac death, target vessel-induced myocardial infarction (MI), stent thrombosis, and target lesion revascularization (TLR). Moreover, the DoCE incidence exhibited no significant disparity between patients with or without ASM (13.1 vs. 6.0%, p = 0.103). Conclusions: While LMCA-ASM was a not uncommon finding post-PCI, it did not correlate with adverse cardiac events in the present study.
Impact of Pulmonary Ventilation Dysfunction on Prognosis of Patients with Coronary Artery Disease: A Single-Center, Observational Study
Authors: Li Yu-Shan , Ren Qiang , Zhang Jian , Liang Yan-Chun , Han Ya-Ling , Zhang Quan-Yu
Published: May 2024

Background: Patients with coronary artery disease (CAD) often experience pulmonary ventilation dysfunction following their initial event. However, there is insufficient research exploring the relationship between this dysfunction and CAD prognosis. Methods: To address this gap, a retrospective observational study was conducted involving 3800 CAD patients without prior pulmonary ventilation disease who underwent cardiopulmonary exercise testing (CPET) during hospitalization between November 2015 and September 2021. The primary endpoint was a composite of major adverse cardiovascular events (MACE), such as death, myocardial infarction (MI), repeat revascularization, and stroke. Propensity score matching (PSM) was used to minimize selection bias between the two groups, with a subgroup analysis stratified by smoking status. Results: The results showed that patients were divided into normal (n = 2159) and abnormal (n = 1641) groups based on their pulmonary ventilation function detected by CPET, with 1469 smokers and 2331 non-smokers. The median follow-up duration was 1237 (25–75% interquartile range 695–1596) days. The primary endpoint occurred in 390 patients (10.26%). 1472 patients in each of the two groups were enrolled in the current analysis after PSM, respectively. However, pulmonary function was not associated with MACE before (hazard ratio (HR) 1.20, 95% confidence interval (95% CI) 0.99–1.47; Log-rank p = 0.069) or after PSM (HR 1.07, 95% CI 0.86–1.34; Log-rank p = 0.545) among the entire population. Nonetheless, pulmonary ventilation dysfunction was significantly associated with an increased risk of MACE in smoking patients (HR 1.65, 95% CI 1.25–2.18; p < 0.001) but not in non-smoking patients (HR 0.81, 95% CI 0.60–1.09; p = 0.159). In addition, there was a significant interaction between current smoking status and pulmonary ventilation dysfunction on MACE (p for interaction < 0.001). Conclusions: Pulmonary ventilation dysfunction identified through CPET was independently associated with long-term poor prognosis in smoking patients with CAD but not in the overall population.
Change in Tricuspid Valve Function after Transvenous Lead Extraction, Predisposing Factors and Prognostic Roles
Authors: Jacheć Wojciech , Polewczyk Anna , Nowosielecka Dorota , Tomaszewski Andrzej , Brzozowski Wojciech , Szczęśniak-Stańczyk Dorota , Duda Krzysztof , Nowosielecka Agnieszka , Kutarski Andrzej
Published: May 2024

Background: Changes in tricuspid valve (TV) function following transvenous lead extraction (TLE) and their impact on long-term survival have not yet been investigated. Methods: From 3633 patients undergoing lead extraction between 2006 and 2021, TV function before and after TLE was evaluated in 2693 patients. Results: After TLE, the TV function remained unchanged in 82.36% of patients, worsened in 9.54%, and improved in 8.10%. Abandoned leads (odds ratio, OR = 1.712; p = 0.044), fibrotic adhesions between leads and TV apparatus (OR = 3.596; p < 0.001), or right ventricular wall (OR = 2.478; p < 0.001) were predisposed to TV worsening. Non-infectious indications for TLE (OR = 1.925; p < 0.001), the severity of tricuspid valve regurgitation (TVR) before TLE (OR = 3.125; p < 0.001), and lead encapsulation (OR = 2.159; p < 0.001) were predictors of improvement in TV function. Although either worsening or improving TV function had no impact on long-term survival in all patients, decreased TVR severity in the subgroup of patients with initial regurgitation grades 3–4 was associated with a better prognosis (hazard ratio, HR = 0.622; p = 0.005). Conclusions: 1. Changes in TV function after TLE were observed in 17.64% of patients. 2. Various factors can predispose to lead-related TV changes, although the common denominator in these events is an extensive buildup of scar tissue. 3. Worsening TV function had no impact on survival after TLE. In patients with severe TV dysfunction, reduction in TVR following TLE was associated with a 40% reduction in mortality during a mean follow-up of 1673 days.
Comparison of the Value of Four Objective Nutritional Indices in Assessing the Long-Term Prognosis of Elderly Patients with Heart Failure with Preserved Ejection Fraction
Authors: Fan Xingman , He Qiongyi , Zhang Kaijie , Lan Xiaohua , Li Yanyan , Zhang Haitao
Published: May 2024

Background: The long-term prognosis of heart failure with preserved ejection fraction (HFpEF) is influenced by malnutrition. Currently, there’s a deficit in objective and comprehensive nutritional assessment methods to evaluate the nutritional status and predicting the long-term outcomes of HFpEF patients. Methods: Our retrospective study included two hundred and eighteen elderly HFpEF patients admitted to the cardiovascular ward at the Air Force Medical Centre from January 2016 to December 2021. Based on follow-up outcomes, patients were categorized into all-cause death (99 cases) and Survival (119 cases) groups. We compared general data, laboratory results, and nutritional indexes between groups. Differences in subgroups based on Triglyceride-Total Cholesterol-Body Weight Index (TCBI), Geriatric Nutritional Risk Index (GNRI), Prognostic Nutritional Index (PNI), and Controlled Nutrition Score (CONUT) were analyzed using Kaplan-Meier survival curves and log-rank test. COX regression was used to identify all-cause mortality risk factors, and the predictive accuracy of the four nutritional indices was assessed using receiver operating characteristic (ROC) curves and Delong test analysis. Results: A total of 101 (45.41%) HFpEF patients experienced all-cause mortality during 59.02 ± 1.79 months of follow-up. The all-cause mortality group exhibited lower GNRI and PNI levels, and higher CONUT levels than the Survival group (p < 0.05). Kaplan-Meier analysis revealed lower cumulative survival in the low GNRI (≤96.50) and low PNI (≤43.75) groups, but higher in the low CONUT (≤2) group, compared to their respective medium and high-value groups. Multifactorial COX regression identified low PNI (≤43.75) as an independent all-cause mortality risk factor in elderly HFpEF patients. ROC and Delong’s test indicated PNI (area under the curve [AUC] = 0.698, 95% confidence interval [CI] 0.629–0.768) as a more effective predictor of all-cause mortality than TCBI (AUC = 0.533, 95% CI 0.456–0.610) and CONUT (AUC = 0.621, 95% CI 0.547–0.695; p < 0.05). However, there was no significant difference compared to GNRI (AUC = 0.663, 95% CI 0.590–0.735; p > 0.05). Conclusions: In elderly HFpEF patients a PNI ≤43.75 was identified as an independent risk factor for all-cause mortality. Moreover, PNI demonstrates superior prognostic performance in predicting all-cause mortality in elderly patients with HFpEF when compared to TCBI, GNRI, and COUNT.
From the history of the Russian abroad. Ivan Ivanovich Ostromyslensky: outstanding contribution to world science
Authors: Volodko Anna
Published: May 2024

The article is dedicated to a prominent member of the Russian diaspora in New York, renowned chemist Ivan Ivanovich Ostromyslensky. I. Ostromyslenski’s research on polymerisation and synthetic rubber production, synthesis of butadiene from ethyl alcohol and sulphur-free vulcanisation made a major contribution to world science. The Ostromyslensky method is still used today in China, India and some other countries. Now, due to the rise in the cost of oil and the development of cheap technologies for producing ethanol from biomass, there is renewed scientific interest in the Ostromyslensky method.
Fate of Kazan art of the Soviet era.
Authors: Kornilova Irina , Nigamaev Albert , Rafikov Azat
Published: May 2024

The article is devoted to the analysis of the series of works, published by Professor N.M. Valeev, Doctor of Philology and dedicated to the milestones of life and creative paths of the outstanding Soviet artists, graduates of the Kazan Art School K.K. Chebotarev and A.G. Platunova. The author of the research pays a great attention both to the unique flavor of the Soviet art of the 1910s-1970s and to some small events of Kazan life, history of the Tatar Republic, local history. While working on his articles and monographs N.M. Valeev used material from different sources: the archive of the Russian Museum, the State Archive of the Republic of Tatarstan, the Scientific Archive of the Institute of Language, Literature and Arts, named after G. Ibragimov, of the Academy of Sciences of the Republic of Tatarstan, the archive of the State Museum of Fine Arts of the Republic of Tatarstan, regional and All-Russian periodicals, catalogs of art exhibitions, theater posters. Autobiographical material is of great use in the research, it helps to reveal K.K. Chebotarev’s and A. G. Platunova’s vision of the artist’s mission in society.
Table based Version of K Nearest Neighbor used for Text Summarization
Authors: Jo Taeho
Published: May 2024

This article proposes the modified KNN (K Nearest Neighbor)algorithm which receives a table as its input data and is applied tothe text summarization. The table based algorithms workedsuccessfully in text mining tasks such as text categorization andtext clustering in previous works, and the text summarization isable to be viewed into a binary classification where each paragraphis classified into summary or non-summary. In the proposed system, atext which is given as the input is partitioned into a list ofparagraphs, each paragraph is classified by the proposed KNNversion, and the paragraphs which are classified into summary areextracted ad the output. The proposed KNN version is empiricallyvalidated as the better approach in deciding whether each paragraphis essential or not in news articles and opinions. In using thetable based KNN algorithm, it is easier to trace results fromcategorizing paragraphs.
Opening Doors to Physical Sample Data Discovery, Integration, and Credit
Authors: Damerow Joan , Raia Natalie , Stanley Val , Choe Saebyul , Borton Mikayla , Byers Neil , Cassidy Ellen , Cholia Shreyas , Edmunds Rorie , Forbes Brieanne , Forrest Kathleen , Goldman Amy , Kunze John , Lafia Sara , Lehnert Kerstin , McIntyre-Redden Marcella , Naples Richard , O'Ryan Dylan , Parker Charles , Plomp Esther , Powers-McCormack Beck , Ramdeen Sarah , Richard Stephen , Thessen Anne , Thompson Cody , Vieglais Dave , Vrouwenvelder Kristina , Wood-Charlson Elisha , Wyborn Lesley , Reddy T.B.K. , Thomer Andrea
Published: May 2024

Physical samples and their associated (meta)data underpin scientific discoveries across disciplines, and can enable new science when appropriately archived. However, there are significant gaps in community practices and infrastructure that currently prevent accurate provenance tracking, reproducibility, and attribution. For the vast majority of samples, descriptive metadata is often sparse, inaccessible, or absent. Samples and associated (meta)data may also be scattered across numerous physical collections, data repositories, laboratories, data files, and papers with no clear linkages or provenance tracking as new information is generated over time. The Physical Samples Curation Cluster has therefore developed ‘A Scientific Author Guide for Publishing Open Research Using Physical Samples.’ This involved synthesizing existing practices, community feedback, and assessing real-world examples to identify community and infrastructure needs. We identified areas of work needed to enable authors to efficiently reference samples and related data, link related samples and data, and track their use. Our goal is to help improve the discoverability, interoperability, use of physical samples and associated (meta)data into the future.
The role of hair endocannabinoid concentrations in clinical symptoms and treatment outcome in female inpatients with posttraumatic stress disorder
Authors: Bergunde Luisa , Woud Marcella Lydia , Shkreli Lorika , Gmelch Lena , Blackwell Simon Edward , Garthus-Niegel Susan , Kirschbaum Clemens , Kessler Henrik , Schmiedgen Susann
Published: May 2024

Background: While available posttraumatic stress disorder (PTSD) treatments are generally successful, 30–40% of patients show limited improvement. The endocannabinoid system may play a role in the aftermath of trauma, in PTSD, and in extinction processes. Therefore, this secondary analysis of a randomized-controlled trial including PTSD inpatients over the course of trauma-focused treatment investigated whether a dysregulated endocannabinoid system is associated with symptom severity and treatment response. Methods: Fifty-four female PTSD inpatients provided hair samples and completed psychometric questionnaires at admission, discharge, and 3-month follow-up. Endocannabinoid (EC: AEA, 1AG/2AG) and N-acylethanolamine (NAE: SEA, OEA, PEA) concentrations were measured in scalp-near 3-cm hair segments. Results: At admission, higher hair AEA correlated with lower depressive and anxiety and higher PTSD symptoms (when controlling for depressive symptoms). Hair NAEs associated with more traumatic experiences. PTSD symptoms improved across treatment, remaining stable at follow-up, but were predicted neither by pre-treatment hair ECs/NAEs nor their changes. Subgroup analyses with those who received exposure treatment tentatively indicated a trend linking higher hair PEA and OEA to lower PTSD symptoms at discharge. Conclusions: Taken together, hair ECs/NAEs may relate differentially to trauma exposure and symptom severity, but not to PTSD inpatient treatment response. Larger-scale research is necessary to confirm this.
NUTRITIONAL STATUS AMONG PREGNANT WOMEN IN THE PUBLIC HEALTH CENTER OF 1 KARANGASEM
Authors: Murnialita Ni Made Galuh , Widyawati Kurniasih
Published: May 2024

Nutrisi dibutuhkan dalam jumlah sangat besar untuk memenuhi status gizi ibu hamil dan untuk kemajuan embrio yang dikandungnya. Masalah bila mengalami status gizi kurang akan mengalami Kekurangan Energi Kronik dan bila kelebihan berat badan atau obesitas dapat menyebabkan risiko terkena penyakit tidak menular diantaranya diabetes gestasional. Diperlukan pengukuran Indek Massa Tubuh untuk mengetahui status Gizi. Data Riskesdas tahun 2018 di Provinsi Bali, prevalensi KEK 13,77% dan data Dinas Kesehatan Kota Denpasar tahun 2018, persentase ibu hamil dengan KEK sebesar 3,2%. Tujuan penelitian ini untuk mengetahui gambaran status gizi ibu hamil di Puskesmas Karangasem. Jenis penelitian ini adalah deskriptif dengan populasi ibu hamil yang datang ke puskesmas. Sampel yang digunakan sebanyak 100 orang ibu hamil dengan menggunakan tehnik purposive sampling dimana pengumpulan data dengan lembar penelitian dan pengukuran Tinggi badan, berat badan dang penghitungan Indek masa tubuh. Data kemudian diolah menggunakan SPSS. Berdasarkan karakteristik responden ibu hamil sebanyak 52% berumur 26-35 tahun, berada pada Trimester 2 sebanyak 58%, tidak bekerja sebanyak 84% dan berdasarkan penghitungan IMT sebagian besar berstatus gizi Normal sebanyak 60%.Gambaran Status Gizi Pada Ibu Hamil di Puskesmas Karangasem 1 sebagian besar pada kategori status gizi normal.
PHYSICAL ACTIVITIES TO IMPROVE SELF-EFFICACY IN PATIENTS WITH CARDIOVASCULAR DISEASE: A LITERATURE REVIEW
Authors: Siregar Khairati , Khusna Lailya , Afridayani Meri , Sardiman Muhammad , Soleman Sitti Rahma , Ardika Noviana Ayu , Effendy Christantie
Published: May 2024

Penyakit kardiovaskular merupakan penyakit kronik yang kasusnya meningkat setiap tahunnya. Seseorang yang terdiagnosa penyakit kardiovaskular seringkali self efficacynya menurun. Self efficacy dibutuhkan untuk menginisiasi dan mempertahankan perilaku serta kepatuhan perawatan. Beberapa alternatif yang dapat digunakan untuk meningkatkan self efficacy seperti aktifitas fisik. Manfaat yang diperoleh antara lain sensitifitas terhadap insulin, menurunkan tekanan darah, menurunkan viskositas darah, memicu produksi nitric oxide dan meningkatkan sensitifitas leptin. Artikel ini bertujuan untuk menemukan hubungan antara aktivitas fisik untuk meningkatkan self efficacy pada pasien dengan penyakit kardiovaskular.Penelusuran literatur dilakukan dengan mencari di data base EBSCO dan Pubmed. Peningkatan self efficacy dilakukan dengan beberapa aktifitas antara lain Eight Silken Movements, Tai Chi, and Strategi Self Efficacy. Beberapa upaya dapat dilakukan berdasarkan tinjauan pustaka dapat digunakan sebagai strategi untuk meningkatkan efiikasi diri pada pasien dengan penyakit kardiovaskular. Peningkatan self efficacy secara langsung dapat menunjang keberhasilan proses pengobatan, meningkatkan kualitas hidup dan menurunkan angka kematian dan kesakitan
PENGARUH METODE SIMULASI BANTUAN HIDUP DASAR (BHD) HENTI JANTUNG TERHADAP KETERAMPILAN DAN EFIKASI DIRI MAHASISWA
Authors: Farilya Mita , Utami Seftiani
Published: May 2024

Kejadiaan Out of Hospital Cardiac Arrest (OHCA) menjadi masalah global dengan angka kematian yang tinggi. Jumlah angka OHCA yang diberikan bantuan hidup dasar lebih besar dilakukan oleh bystander dan terbukti dapat meningkatkan angka harapan hidup. Tempat pendidikan memberikan akses yang lebih besar dalam penyebarluasan pengetahuan tentang bantuan hidup dasar sehingga dapat meningkatkan angka bystander. Hal tersebut menjadi dasar diperlukannya pemberian pembelajaran bantuan hidup dasar henti jantung dengan metode yang efektif pada mahasiswa. Tujuan: Mengetahui pengaruh metode pembelajaran simulasi bantuan hidup dasar terhadap keterampilan dan efikasi diri mahasiswa. Penelitian ini menggunakan desain quasy eksperimental dengan one group pretest-posttest design. Pengambilan sampel mengunakan teknik simple random sampling, didapatkan sampel sejumlah 20 responden. Data dikumpulkan dengan kuesioner dan lembar observasi. Analisa data menggunakan SPSS. Hasil: Terdapat pengaruh yang signifikan antara keterampilan dan efikasi diri melakukan BHD metode simulasi dengan pvalue 0,018. Kesimpulan: Terdapat peningkatan keterampilan dan efikasi diri mahasiswa setelah diberikan pembelajaran metode simulasi BHD.
PENGARUH EMPOWERMENT TERHADAP SELF CONCEPT PASIEN DENGAN HIV/AIDS
Authors: Drajad Pamukhti Bagas Biyanzah , Khusna Lailya , Margatot Didik Iman
Published: May 2024

Pendahuluan: Human immuno-defisiensi virus (HIV) adalah virus yang melemahkan kemampuan sistem kekebalan tubuh untuk melawan segala penyakit yang menyerang tubuh yang menyebabkan beberapa penyakit menyerang tubuh (AIDS). Perubahan-perubahan bentuk tubuh akibat HIV/AIDS dan pengobatannya dapat menyebabkan gangguan konsep dirinya yaitu fisik, sosial dan psikologi. Gangguan konsep diri seperti penurunan berat badan berlebihan, perubahan penampilan, penurunan berat badan, gangguan kulit, dan mudah lesu, stigmasisasi, diskriminasi, isolasi sosial,  stres, keyakinan diri rendah, mengalami kecemasan dan depresi. Empowerment memiliki aspek penting karena berhubungan dengan hal yang paling dibutuhkan klien untuk menyelesaikan masalah yang dihadapi khususnya masalah kesehatan, dan respons terhadap informasi (responding to information) merupakan tanggapan pasien terhadap berbagai informasi yang diperoleh dari sumber daya yang ada. Metode: Penulisan ini menggunakan metode literature review. Sumber kepustakaan berasal dari buku, jurnal dan artikel dengan kata kunci “empowerment”, “self concept“ dan “HIV/AIDS”. Hasil: Proses empowerment dapat meningkatkan self concept pasien terhadap HIV/AIDS  dengan melalui pengetahuan, dan sikap respon terhadap informasi, karena pasien memilik hak untuk menerima layanan yang sesuai, menerima informasi yang sesuai dan memadai, pasien juga dapat memilih secara bebas dan memutuskan layanan kesehatan, serta memiliki hak untuk mengakses sistem pengaduan yang efektif. Kesimpulan: Empowerment dapat mempengaruhi self concept melalui pengetahuan, dan sikap respon terhadap informasi
GAMBARAN TINGKAT PENGETAHUAN MAHASISWA TERKAIT BANTUAN HIDUP DASAR (BHD) DI UNIVERSITAS ‘AISYIYAH SURAKARTA
Authors: Margatot Didik Iman , Khusna Lailya , Drajad Pamukhti Bagas Biyanzah
Published: May 2024

Insiden henting jantung atau henti nafas merupakan kejadian gawat darurat yang sering ditemui di berbagai tempat yang disebabkan oleh berbagai faktor seperti memiliki riwayat penyakit jantung dan yang disebabkan oleh kecelakaan. Berdasarkan data dari Wolrd Health Organization (WHO, 2021) menyebutkan bahwa penyebab kematian nomor satu secara global adalah penyakit jantung. Sebanyak 17,8 juta jiwa setiap tahun mengalami kematian karena serangan jantung. Tahun 2020 sebanyak 1,9 juta orang meninggal setiap tahun dikarenakan kecelakaan lalu lintas yang ada di Indonesia. Berbagai penanganan kegawatdaruratan yang dapat di implementasikan pada kejadian henti nafas maupun henti jantung, salah satunya yaitu pemberian Bantuan Hidup Dasar (BHD). Bantuan hidup dasar merupakan tindakan yang paling penting dalam memberikan pertolongan pertama dan sangat membantu saat seseorang mengalami henti jantung, sumbatan nafas, hingga tidak sadarkan diri agar dapat mencegah keadaan yang lebih parah. Pemberian pelatihan bantuan hidup dasar sangat penting dimiliki oleh masyarakat umum hingga mahasiswa agar dapat membantu korban yang mengalami henti jantung maupun henti nafas yang berdampak pada kematian. Apabila seorang memiliki pengetahuan yang baik terkait bantuan hidup dasar maka akan memiliki motivasi yang tinggi untuk menolong korban yang mengalami kecelakaan, henti jantung, serta henti nafas.
Les préférences des Québécois envers la redistribution : l'exception canadienne?
Authors: Déry Axel , Jacques Olivier , Dinan Shannon
Published: May 2024

Est-ce que le modèle québécois de politiques sociales reflète une opinion publique plus favorable aux services publics et à la redistribution de la richesse? Pour répondre à cette question, les auteurs utilisent trois séries de sondages portant sur deux questions centrales dans l’étude comparée des préférences des citoyens à l’État-providence : l'appui à la redistribution du revenu (1986 à 2021) et les préférences quant à la taille des services publics (2019 à 2023). Dans ces trois séries de sondages, ils observent un appui significativement plus élevé envers la redistribution et les services publics chez les répondants québécois que chez les répondants des autres provinces, bien que les répondants des provinces de l'Atlantique affichent aussi un appui élevé. Les électeurs conservateurs et les citoyens plus aisés sont significativement moins en faveur des services publics et de la redistribution hors du Québec.
Painting with Metal: When History and Art Meet Thermal Spray
Authors: Nastic Aleksandra , Jodoin Bertrand , Fitzgerald Christine , Desaulniers Sylvain , Pouliot Luc , MacDonald Daniel , Caio Fernanda , Dubois Guillaume , Duval Alexandre , Tessier Vincent , Etienne Christopher
Published: May 2024

Cold spray technology provides a multidisciplinary approach to additive manufacturing at the intersection of science and art. This article describes the novel use of cold dynamic spray technology to create a large and complex 3D artwork that incorporates six different metals.
Electro-Thermal Simulation and Reliability of a Ball Grid Array
Authors: Hami Norelislam El , Koulou Aicha , Zemzami Maria , Hami Abdelkhalak El
Published: May 2024

The influence of electric current flow and electrically induced Joule heat on thermal stress for weld joint cracks at both interfaces is still not fully comprehended. This article investigates the effect of subjecting the ball grid array package to a cyclic current input. Current density, Joule effect, and temperature curves are examined.
Differential Laser Voltage Probe: A Brief Overview and Thoughts on What Could Come Next
Authors: Dickson Kristofor
Published: May 2024

Differential laser voltage probe simultaneously acquires waveform data from a single target while the device under test fluctuates between passing and failing test outcomes. This article describes the use of this technique and how it could be affected by trends in the microelectronics industry.
THE LAW OF RESTITUTION OF UNJUST ENRICHMENT IN MALAYSIA: A SEARCH FOR PRINCIPLE, POST ‘DREAM PROPERTY’
Authors: Alias Siti Aliza , Ida Madieha Abd Ghani Azmi
Published: May 2024

Part VI of the Malaysian Contracts Act 1950 ('of certain relations resembling those created by contract') embodies the old notion of quasi-contract or implied contract - what is now known under English Law and in other Common Law jurisdictions as restitution of unjust enrichment. The landmark decision of our Federal Court, in the case of Dream Property Sdn Bhd v Atlas Housing Sdn Bhd gave recognition to ‘unjust enrichment’ as a separate cause of action in Malaysia. However, the law of unjust enrichment in Malaysia is at its infancy and still developing. This paper focuses on two main questions that arise from that decision. Firstly, on the legal consequences of the court's apparent adoption of the civil law 'absence of basis' approach to determine whether an enrichment is 'unjust', rather than the traditional 'unjust factor' approach under English Common Law, and how this might affect the future development of unjust enrichment as a separate cause of action in Malaysia. Secondly, on the larger question of what the law of unjust enrichment in Malaysia now is or should be - whether the correct approach is to develop unjust enrichment within an apparent ‘dual legal regime’ ie. the statutory regime under the Contracts Act 1950 and the Common Law regime; or rather to use the Common Law by analogy to develop the contents (ie. detailed rules and principles) of the Contracts Act 1950 (Part VI) in a principled approach that may require modern restatement for  practical use today. Using the doctrinal and comparative methodology, it is the paper’s findings that the latter ‘unified’ approach is preferable as a way forward for Malaysian courts to develop our law of unjust enrichment and using the ‘unjust factor’ approach, for reasons outlined in this paper.
CURRENT PROBLEMS OF LIFTING SANCTIONS IMPOSED ON LEGAL ENTITIES
Authors: Sus Yulia S. , Hrachova Oleksandra Yu.
Published: May 2024

Aim. The aim of this study is an in-depth analysis of the effectiveness and consequences of the application of sanctions in international relations, aimed at studying the reaction to the actions of the russian federation in the context of a full-scale armed conflict on the territory of Ukraine, which began on February 24, 2022. Special attention is paid to interaction with legal entities affected by sanctions.
Materials and methods. Our approach is based on a systematic analysis of the internal legislation of Ukraine regarding sanctions: the Law of Ukraine "On Sanctions" and other normative legal acts. In parallel, the European Convention on the Protection of Human Rights and Fundamental Freedoms (ECHR), as well as statistical data on their application, is studied. To achieve the goals of the work, general scientific and special methods of scientific knowledge are used. According to the current legislation of Ukraine, sanctions against legal entities are established in order to comply with obligations at the international level. The Law of Ukraine "On Sanctions" defines specific legal principles and procedures for the application of sanctions. At the same time, within the framework of international relations, Ukraine recognizes and adheres to conventions that regulate sanctions and their cancellation. The European Convention for the Protection of Human Rights and Fundamental Freedoms (ECHR) forms the basis for the protection of the rights and freedoms of citizens in the context of the application of sanctions.
Results. In the course of the study, it was established that the response to acute geopolitical conflicts leads to an increase in the number of sanctions. It was also found out that there is an objective need for a deep theoretical study of the problems of cancellation criteria and the risks of repeated financing of military operations over time.
Conclusions. The conclusions indicate the need for unified approaches to sanctions and their cancellation at the international level. Particular attention is paid to the issue of principles that should be enshrined in legislation: the need to increase transparency and regulate the procedure for the introduction of sanctions, optimization of the procedure for consideration of cases on the cancellation of sanctions, etc. It is recommended to establish clear criteria for lifting sanctions and create a special commission to objectively assess the fulfilment of conditions.
Data mining approach for prediction of academic success in open and distance education
Authors: Tosun Selma , Bakan Kalaycıoğlu Dilara
Published: May 2024

Predicting and improving the academic achievement of university students is a multifactorial problem. Considering the low success rates and high dropout rates, particularly in open education programs characterized by mass enrollment, academic success is an important research area with its causes and consequences.
This study aimed to solve a classification problem (successful or unsuccessful), predict students’ academic success, and identify those at risk. The primary objective was to predict the academic success status with 26,708 students enrolled in Istanbul University open and distance education programs between 2011 and 2017. Predictions were based demographic data and success grades in Turkish, Atatürk's Principles and History of Revolution, English, and Disaster Culture courses. The study utilized classification models from supervised learning algorithms and was conducted using the SPSS Modeler 18 program. Initially, the data was divided into 70% training and 30% test data. Then, models were constructed by using Random Forest, Tree-AS, C&RT, C5.0, CHAID, QUEST, Naive Bayes, Logistic Regression, NeuralNet, and SVM algorithms. Model performances were compared according to accuracy, sensitivity, specificity, F1 score, positive predictive value, negative predictive value, and Matthews Correlation Coefficient criteria. The C&RT model demonstrated the best performance, achieving the highest specificity value of 0.915.
Peningkatan Kinerja Pertumbuhan Benih Ikan Gabus (Channa striata) dengan Probiotik EM4
Authors: Jayadi J , Harlina H , Hamdillah Andi , Nursyahran N , Suryadi S
Published: May 2024

The decreasing population of snakehead fish (Channa striata) in nature needs to be preserved through cultivation. The use of probiotics in cultivation can support increased production. This study aimed to determine the effect of the frequency of probiotics on survival, growth, feed conversion, and body proximate in snakehead fish fry for 60 days. The study was conducted using an experimental method with a completely randomized design (CRD) consisting of 4 treatments and 3 replications. The treatment is the frequency of giving probiotics, including once a day, twice a day, three times a day, and without probiotics (control). The results showed that the frequency of probiotic administration affected survival, growth, feed conversion, and proximate content of snakehead fish seed bodies. The best frequency is the provision of probiotics twice a day.
Pertumbuhan dan Produksi Genotipe Kedelai (Glycine max L. Merrill) dengan Aplikasi Jenis Mikoriza di Lahan Kering
Authors: Widiati Bibiana Rini , Idrus Muh. Izzdin , Wahditiya A. Adriani
Published: May 2024

One of the efforts to increase the production of soybean plants in a dry land, which is environmentally friendly with mycorrhizal inoculation, will help absorb water tightly bound to soil micropores and absorb plant nutrients. This research aimed to study the effect of MVA application on increasing the growth and production of soybean genotypes on dry land, determining the type of mycorrhizae that is most compatible with soybean genotypes on dry land, is there an interaction between soybean genotypes and mycorrhizal types so that it is adaptive on dry land. Use Divided plot design (RPT), as follows: Main plot (PU) consists of 6 genotypes of the 4th generation (g) viz : g1 (gM50Gy); g2 (gO50Gy); g3 (gT50Gy); g4 (gM); g5 (gO); g6 (gT). Subplot (AP) is kind mycorrhizae (M), namely control (without mycorrhizae (m0), Glomus etunicatum (m1), Gigaspora margarita, (m2), mixedGlomus etunicatum and the Gigaspora margarita (m3). Each treatment on the main plot and subplots were combined so that there were 24 treatment combinations. The results showed that the soybean genotype was g1 (gM50Gy); g2 (gO50Gy); g3 (gT50Gy) are well adapted to dry land, which is indicated by stomata length and width, higher canopy and root dry weight, and with lower Al uptake. A mycorrhizal application mix Glomus etunicatum and Gigaspora margarita showed the best results on observing length and number of stomata, shoot and root dry weight, root Al uptake, number of filled pods, and seed weight per plot. Treatment (gT50Gy) with mycorrhizal applications mix Glomus etunicatum, and Gigaspora margarita gave the best results on the number of stomata, phosphorus uptake.
Performa Benih Udang Windu yang Diberi Artemia Diperkaya Taurin
Authors: Ridwan R , Baiduri Moh. Adnan
Published: May 2024

This study aimed to analyze the performance of tiger prawn Penaeus monodonseed which were fed taurine-enriched Artemia. The study was conducted by using a completely randomized design.The treatment in this research was taurine enrichment dosage of Artemiathat consist of 4 levels: 0 gL-1 (DPT-0), 0.5 gL-1 (DPT-0.5), 1.0 gL-1 (DPT-1.0) and 1.5 gL-1 (DPT-1.5) in triplicate. Larvae stocked at a density of 50 individu.L-1 were fed Artemianauplii from Mysis-3 to PL-12 stages. Measurement and analysis data to compare the effects of these treatments were tested by analysis of variance (ANOVA) followed by Duncan's multiple range test at a significance level of 0.05. The results showed that the taurine content of Artemia increased significantly and linearly with the enrichment dose of taurine. Furthermore, the specific growth rate and visual quality of larvae increased significantly by feeding taurine-enriched Artemiaof 1.0 gL-1, but increasing the taurine enrichment dose to 1.5 gL-1 in the Artemia was not followed by an increase in these parameters. The vitality and resistance of larvae increased significantly and linearly with increasing in taurine enrichment dose, whereas the survival rate for larvae only increased significantly with 0.5 gL-1 taurine-enriched Artemia. Based on these results, the best post-larval performance of tiger prawns was obtained by feedingArtemia enriched with taurine 1.0–1.5 gL-1.
PERTUMBUHAN BIBIT KOPI BERDASARKAN TINGKAT KEMATANGAN BUAH DAN APLIKASI CENDAWAN ENDOFIT
Authors: Irma I , Syamsia S , Idhan Abubakar , Firmansyah Amanda Patappari
Published: May 2024

Kopi memiliki masa dormansi yang cukup lama karena memiliki kulit biji yang keras, sehingga perkecambahan membutuhkan waktu lama. Salah satu upaya untuk mempercepat masa dormansi benih kopi adalah menggunakan benih matang secara fisiologi dan aplikasi cendawan endofit. Penelitian ini bertujuan untuk mengetahui tingkat kematangan buah dan jenis cendawan dapat mempercepat perkecambahan dan pertumbuhan benih kopi. Penelitian ini disusun menggunakan Rancangan Acak Kelompok (RAK) dengan 2 perlakuan yaitu tingkat kematangan buah (berdasarkan warna buah kopi) dan jenis cendawan endofit. Tingkat kematangan buah kopi (warna kulit buah kopi) terdiri atas 4 taraf yaitu: buah kopi berwarna cokelat, merah, orange dan kuning. Faktor kedua yaitu jenis cendawan endofit dengan 2 taraf yaitu: isolate CE-1, isolate CE-5, dan sebagai tanpa perlakuan. cendawan endofit sebagai kontrol. Parameter yang diamati adalah persentase kecambah (%), pecahnya kotiledon (hari), daun Lembaga terbuka sempurna (hari), munculnya daun pertama (hari), tinggi bibit (cm), jumlah daun (helai), panjang akar (cm), bobot segar tanaman (gr), bobot segar akar (gr), bobot sekar daun (gr), bobot kering tanaman (gr), bobot kering akar (gr), bobot kering daun (gr). Hasil penelitian menunjukkan bahwa tingkat kematangan buah kopi berpengaruh nyata terhadap persentase kecambah, munculnya daun pertama dan bobot segar tanaman. Tingkat kematangan buah terbaik untuk persentase kecambah adalah warna merah dengan persentase kecambah 98,5%, munculnya daun pertama (44 hari), dan bobot segar tanaman (0,25 gr). Jenis isolate cendawan endofit berpengaruh nyata terhadap persentase kecambah, daun lembaga terbuka sempurna dan munculnya daun pertama. Jenis cendawan endofit CE-5 menunjukkan hasil terbaik pada parameter persentase kecambah (93,06%), daun lembaga terbuka sempurna (28 hari) dan munculnya daun pertama (46 hari). Penggunaan buah kopi berwana merah dengan aplikasi cendawan endofit dapat digunakan untuk meningkatkan perkecambahan dan pertumbuhan bibit kopi.
Aplikasi Pemberian Ekstrak Bawang Merah (Allium Cepa L.) Terhadap Pertumbuhan Stek Batang Gaharu (Aquilaria malaccensis Lam.)
Authors: Ponisri P , Maliki Syaiful , Aran Bernadus
Published: May 2024

Penelitian ini bertujuan mengetahui pengaruh perbedaan konsentrasi dan menghasilkan pertumbuhan stek batang Aquilaria malaccensis Lam.paling baik. Metode yang digunaka  metode eksperimen  menggunakan Rancangan Acak Lengkap  terdiri dari 5 perlakuan dan 3 ulangan, setiap  percobaan membutuhkan 5 stek batang. Jumlah sampel sebanyak 75 stek batang. Perlakuan yang diberikan  ZPT asal bawang merah  terdiri dari 5 konsentrasi yaitu:  Z0 : tanpa perlakuan/ 0 %,  Z1 : ZPT bawang merah 10 %,  Z2 : ZPT  bawang merah 20 %,  Z3 : ZPT  bawang merah 30 %r,  Z4 : ZPT bawang merah 40 %. Data diperoleh jumlah tunas, daun, panjang daun, dan lebar daun diolah dan dianalisis menggunakan analisis ragam , apabila berpengaruh nyata dilakukan uji lanjut menggunakan uji BNT 5 %. Bahwa  konsentrasi ekstrak bawang merah terhadap pertumbuhan stek batang Aquilaria malaccensis Lam. berpengaruh sangat nyata pada perlakuan Z4 terhadap tunas, jumlah daun, dan panjang daun dengan  konsentrasi paling baik 40 %. Rata-rata tertinggi pada jumlah tunas tanaman gaharu terdapat pada umur 21 HST pada perlakuan Z4 (40% ekstrak bawang merah) dengan jumlah tunas mencapai 0,8 tunas,sedangkan rata-rata terendah padah jumlah tunas gaharu terdapat pada umur 14 HST dengan perlakuan Z0, Z1 dan perlakuan Z2 tidak bertunas. Rata-rata tertinggi pada jumlah daun tanaman gaharu terdapat pada umur 77 HST pada perlakuan Z4 (40% ekstrak bawang merah) dengan jumlah daun mencapai 6,06 helai,sedangkan rata-rata terendah padah jumlah daun gaharu terdapat pada umur 28 HST dengan perlakuan Z0 , Z1 dan perlakuan Z2 yang tidak memiliki daun. Rata-rata pertumbuhan panjang daun yaitu 5,27 pada perlakuan  Z4. Rata-rata tertinggi pada lebar daun tanaman gaharu terdapat pada umur 77 HST pada perlakuan Z4 (40% ekstrak bawang merah) dengan lebar daun mencapai 1,2 cm ,sedangkan rata-rata terendah padah lebar daun gaharu terdapat pada umur 28 HST dengan perlakuan Z0, Z1 dan perlakuan Z2  yang tidak memiliki daun.
Ekspansi Pakan Alami Tepung Ubi Jalar Terhadap Intensitas Kecerahan Warna Ikan Mas Koi (Cyprinus carpio)
Authors: Wahyu Farhanah , Andi Chadijah
Published: May 2024

Koi carp (Cyprinus carpio) is one of the attractive ornamental fish to be cultivated because it has a gorgeous color and high economic value, so koi carp is in great demand by the public. The beautiful color of koi carp is influenced by the presence of natural pigments in fish; to release that color, it is necessary to add color pigments from synthetic substances. One of the natural ingredients that contain color pigments is purple sweet potato. This study aims to determine the effect and the correct dose of adding sweet potato flour to the intensity of the color brightness of koi carp (Cyprinus carpio). This research was carried out in stages, starting with the supply of raw materials for feed and carp koi (Cyprinus carpio). Then, the use of fish color measuring instrument parameters, namely toca color, measurement of absolute growth, survival rate, feed conversion, and feed efficiency. In the next stage, the research focused on fish maintenance and using optimal feed doses against changes for 90 days. The study's results showed that the highest change in color brightness was in treatment C (of purple sweet potato flour 15%) with a value of 6. Then, treatment A (5%), as much as 5.56, followed by treatment D (control), did not experience an increase in brightness color. Treatment B (10%) has the lowest color brightness level of 4.89. The results of these numbers are adjusted to the analysis test results (p> 0.05), which shows that the feeding of purple sweet potato flour has no significant effect on changes in the color's brightness level, and the results of the efficiency of feed utilization.
IDENTIFICATION OF SOME CONCENTRATION OF VEGETABLE WASTE COMPOST EXTRACTS AND ITS INFLUENCE TO INCREASING NUTRIENT OF CULTIVATED SOILS
Authors: Septyani Ika Ayu Putri , Dalimunthe Badrul Ainy , Sepriani Yusmaidar
Published: May 2024

Tanah di perkarangan sebagian besar memiliki kandungan bahan organik, unsur hara. sedikit dan luasannya relatif sempit. Bahan organik dapat dibentuk melalui ekstrak kompos sayur. Tujuan penelitian ini adalah untuk melihat pengaruh konsentrasi ekstrak kompos dalam memperbaiki ketersediaan hara dan perbaiki sifat kimia. Tempat penelitian ini dilakukan Rantau Prapat, Kec rantau selatan, Kabupaten labuhanbatu. Kota ini berada antara 99o33’ BT - 100o22’ BT dan 01o41’ LU - 02o44’ LU. Penelitian ini menggunakan dua tahap. Tahap pertama adalah untuk menginvestigasi perbedaan konsentrasi ekstrak kompos menggunakan uji statistik uji t berpasangan pada taraf 5%. Pada tahap kedua menggunakan Rancangan Acak Lengkap (RAL) dengan 3 perlakuan dan 18 ulangan, Penelitian ini menunjukan bahwa ekstrak kompos memiliki formulasi perlakuannya adalah 1:5 dan 1:10 yang berpengaruh nyata dilanjutkan dengan uji lanjut Beda Nyata Terkecil (BNT) pada taraf 5%. Hasil penelitian ekstrak kompos menunjukkan bahwa 1:5 mempunyai karakteristik kimia lebih tinggi seperti pH=6,83%, C-Organik=22.5%, N=0,95%, P=0,37%, K=8,8%. Penelitian ini menunjukan bahwa pemberian ekstrak kompos 1:10 dapat meningkatkan unsur hara pada tanah perkarangan  memberikan hasil terbaik serta menunjukan ketersediaan hara ditanah perkarangan dengan hasil seperti pH=4,92%, C-Organik=4,11%, N-total= 16,3%, P-brayl=251,37%, K-dd=10.9%,dan KTK=26,34%. Dapat disimpulkan bahwa 1:10 lebih direkomendasikan sebagai bahan amelioran tanah, karena 1:10 lebih mudah melepaskan unsur hara.
Formulasi Nugget Berbahan Dasar Ikan Terbang (Parexocoetus brachypterus), Tepung Jewawut (Setaria italica (L.) Beauv.) dan Daun Kelor (Moringa oleifera) Sebagai Menu PMT Pencegah Stunting
Authors: Ismail Ayu Indayanti , Yuniati Dewi , Aryanti Novi
Published: May 2024

The high prevalence rate of stunting in West Sulawesi Province, which reached 33.8, places West Sulawesi in second place in the province with the highest stunting in Indonesia. One effort to prevent stunting is to diversify the intake of complementary foods for children aged 6-23 months by utilizing local natural resources. This research aims to formulate flying fish, barley flour, and Moringa leaves as a functional food in processed nuggets as a menu for Supplementary Feeding (PMT) for babies under two years old. The research method was carried out in three stages, namely, the nugget formulation in two formulas, namely F1 and F2. Next, an organoleptic test is carried out to select the best formula, followed by a nutritional content analysis, which includes proximate analysis and mineral testing. The research results showed that the nugget formula selected was based on organoleptic tests on 30 panelists, namely F1 nuggets with a mixture of 175 g of flying fish, 75 g of barley flour, and 10 g of moringa leaves. These nuggets contain nutrients per 100 grams, namely protein 14.36 g, carbohydrates 27.83 g, fat 5.53 g, crude fiber 1.22 g, iron 62.78 mg/kg, calcium 97.53 mg/kg, and zinc 15.52 mg/kg. Therefore, nuggets with the selected formula are rich in the nutrients needed in complementary breast milk foods to prevent stunting.