bluuebunny/crossref_metadata_2025 huggingface dataset:
ENHANCING QUALITY OF LIFE IN THE CAMPUS COMMUNITY: THE EFFECTIVENESS OF THE GREEN CAMPUS INITIATIVE
Authors: Abdullah Siti Nor Fazillah , Kamarudin Mohd Khairul Amri , Abd Wahab Noorjima , Purba Nelvitia , Sanopaka Endri
Published: February 2024

This study seeks to investigate the existing green practices implemented at UniSZA to achieve sustainability and enhance the quality of life for campus society. This study employs quantitative methodologies, specifically utilizing questionnaire survey techniques to gather empirical data. The Pearson Correlation and Cluster Analysis were utilized to determine the correlation among the questions. The result indicates that there is a positive correlation between all questions. Only some questions have weak correlations which correlated to the recognition of the significance of sustainability and the adoption of tangible measures to translate its principles into reality. The cluster analysis successfully sorted the 20 questions related to green campus and perceived quality of life into three distinct clusters: high perceived quality of life, moderate perceived quality of life, and low perceived quality of life. The findings indicated that the UniSZA society expressed a good perceived quality of life regarding their mean score. However, in terms of satisfaction with their campus society, UniSZA still lacks the green campus aspect implementation. Therefore, it is imperative to heighten awareness of the green campus aspect through the collaboration of the entire campus society, emphasizing the importance of green technology in achieving sustainable development.
TEMPORAL ANALYSIS AND PREDICTIVE MODELING OF AMBIENT AIR QUALITY IN HULU LANGAT DISTRICT, SELANGOR, MALAYSIA: A CHEMOMETRIC APPROACH
Authors: Abdullah Aiman , Mohd Saudi Ahmad Shakir , Shafii Nur Zahidah , Kamarudin Mohd Khairul Amri , Muhammad-Sukki Firdaus
Published: February 2024

One of the most important environmental problems facing the globe today is air pollution. The centre area for the local populace is the Hulu Langat district, which borders Kuala Lumpur, the capital. The purpose of this study is to look at how the ambient air quality varies in Hulu Langat, Selangor. The Air Quality Division of the Malaysian Department of Environment provided five years' worth of secondary data on the air quality at Hulu Langat. The database included five primary air pollutant characteristics sulphur dioxide (SO2), carbon monoxide (CO), ozone (O3), nitrogen dioxide (NO2), and particulate matter with a diameter of 10 microns or less (PM10), in addition to data from the Air Pollutant Index (API). Chemometric analysis was used to examine the results. According to the results, SO2, NO2 and PM10 had the greatest correlations with API readings. A statistical process known as statistical control (SPC) showed that certain PM10 values were over national recommendations and control limits. The artificial neural network method's air quality prediction model demonstrated good accuracy with real data (R2 = 0.9). The results of this investigation indicated a strong correlation between the Hulu Langat air quality data. In order to achieve sustainable environmental practices in the future, it is imperative to engage in extensive collaboration across environmental departments and relevant authorities and engage in continuous monitoring of air quality.
Caracterización fisiológica y actividad biocontroladora de levaduras filosféricas sobre Penicillium digitatum en poscosecha de naranja
Authors: Mejía Cindy , Uribe Liz , Cotes Alba Marina , Zapata Jimmy
Published: February 2024

El moho verde causado por Penicillium digitatum es la enfermedad más limitante en la postcosecha de cítricos. Dado que los conidios del hongo están en el aire éste puede afectar los frutos en la precosecha, en la planta de empaque, durante el transporte, en el almacenamiento y en el mercado. Dentro de los microorganismos utilizados como agentes de control biológico, las levaduras se destacan por su versatilidad fisiológica, ya que asimilan una gran variedad de sustratos (Andrews y Back, 2004). Igualmente colonizan y se reproducen rápidamente sobre la superficie vegetal y toleran condiciones ambientales adversas (Elad 1996; Mercier y Lindow, 2000). El objetivo de este trabajo fue caracterizar fisiológicamente 21 accesiones de levaduras nativas y seleccionar las que presentaran alta actividad biocontroladora sobre Penicillium digitatum, con miras al desarrollo futuro de un bioplaguicida para el control de enfermedades en poscosecha.
Toxic Relationships Described by People With Breast Cancer on Reddit: Topic Modeling Study (Preprint)
Authors: Davidson Cara Anne , Booth Richard , Jackson Kimberley Teresa , Mantler Tara
Published: February 2024

BACKGROUND

Social support is essential to promoting optimal health outcomes for women with breast cancer. However, an estimated 12% of women with breast cancer simultaneously experience intimate partner violence (IPV; physical, psychological, or sexual abuse by an intimate partner). Women who experience IPV during breast cancer may lack traditional social support, and thus seek out alternative sources of support. Online community forums, such as Reddit, can provide accessible social connections within breast cancer–specific communities. However, it is largely unknown how women with breast cancer use Reddit to describe and seek support for experiences of IPV.

OBJECTIVE

This study aims to explore how patients with breast cancer describe toxic relationships with their partners and immediate family members on Reddit.

METHODS

This exploratory, cross-sectional, topic-modeling study analyzed textual data from 96 users in the r/breastcancer subreddit in February 2023. The meaning extraction method, inclusive of principal component analysis, was used to identify underlying components. Components were subjected to sentiment analysis and summative content analysis with emergent categorical development to articulate themes.

RESULTS

Seven themes emerged related to toxic relationships: (1) contextualizing storytelling with lymph nodes, (2) toxic behavior and venting emotions, (3) abandonment and abuse following diagnosis, (4) toxic relationships and social-related fears, (5) inner strength and navigating breast cancer over time, (6) assessing social relationships and interactions, and (7) community advice and support. Toxic relationships were commonly characterized by isolation, abandonment, and emotional abuse, which had profound emotional consequences for patients. Reddit facilitated anonymous venting about toxic relationships that helped patients cope with intense feelings and stress. Exchanging advice and support about navigating toxic relationships during breast cancer were core functions of the r/breastcancer community.

CONCLUSIONS

Findings emphasized the value of Reddit as a source of social support for patients with breast cancer experiencing toxic relationships. Clinicians who understand that many patients with breast cancer experience toxic relationships and considerable psychological sequelae are better prepared to support their patients’ holistic well-being. Further investigation of Reddit as a possible resource for advice, information, and support has the potential to help inform clinical practice and subsequently, patient health outcomes.
Sentimientos, emociones y engaño desde la perspectiva de trabajo social
Authors: Gamboa Guerrero Sergio
Published: February 2024

El siguiente artículo consiste en una propuesta para trabajar los sentimientos y las emociones desde el trabajo social, rompiendo con los esquemas tradicionales de abordar estos temas mediante los trastornos y la salud mental. La primera parte establece las bases conceptuales y se realiza una aproximación metodológica mediante el uso de la transdisciplina. La segunda parte utiliza la categoría conceptual del engaño para plantear ventajas y desventajas dentro de nuestra disciplina. En términos generales, este artículo presenta alternativas para invitar a los lectores a innovar y reflexionar desde la perspectiva contemporánea sobre lo que hacemos con la finalidad de crecer como disciplina y como profesión.
Cincuenta años del trabajo social mexicano, una historia de vida
Authors: Valero Chávez Aída I.
Published: February 2024

La historia es la memoria social de los pueblos. Ella conserva y transmite vivencias de los grupos humanos; las más significativas,las trascendentes. La historia nos permite valorar y enjuiciar situaciones pasadas y prever para el futuro. En este texto trato sobre las vicisitudes que me han tocado vivir, es decir, seleccionando todo aquello relevante que considero vital en el recuento de estos años.
Suspicious Activity Tracking
Authors: Renushe Prof. Mrs. A. H. , Poojary Miss.Varsha , Shirsat Miss. Salonee , Sonawale Miss. Sakshi , Yadav Miss. Pratiksha
Published: February 2024

Abstract: Our offering includes a deep neural network model that can identify firearms in photographs and a machine learning and computer vision pipeline that can detect abandoned luggage in order to identify potential gun-based crime and circumstances involving abandoned luggage in surveillance film. Unusual behavior the technique of identifying undesired human activity in locations and circumstances is called detection. To do this, footage is converted into frames, and the processed frames are then used to analyze the people's sports. YOLOv3 is used to find a niche, in dubious sports like lock breaking and bag snatching, among others. Our gadget has a superb processing pace in addition to appropriate accuracy of detection. It is harder for computers to detect things in videos compared to images because of issues like blurriness or things getting blocked. They propose a solution called Shot Video Object Detector, which is a faster kind of detector for videos. It works by combining information from nearby frames to make better guesses about where objects are. Unlike other methods, Shot Video Object Detector does this by figuring out how things move between frames and then using that info to combine features. It also creates new features by borrowing information directly from neighboring frames using a special structure. Automated surveillance in public areas plays a crucial role in upholding law and order and proactively identifying potential risks to the public. Not only does the procedure automatically identify and detect known crooks, but it also tracks people's and things' movements and uses machine learning algorithms to alert the authorities to any questionable activity
Study the Diversity of Nocturnal Moths in Agricultural Field of Western Maharashtra Region
Authors: Phadtare Shekhar , Ragade Vinod R. , Gaikwad Ravindra , Takawane Priyanka
Published: February 2024

Abstract: Study of moths is important as they are significant part of the ecosystem. A study on macro-moths was conducted at agricultural field of Western Maharashtra region from month of June 2022 to May 2023. The Main aim of study to acquire the detail information of moths found in agricultural filed of District Satara and Pune. During the study period, a total 2012 specimen’s moths were observed. In addition, the number of families recorded from agricultural field of Western Maharashtra is also high, 20 families and 57 species occurred in desired location. Agricultural field of Western Maharashtra shows moths diversity. So, moth diversity was studied from Western Maharashtra from two sites including Phaltan and Baramati taluka respectively. These two sites have a few species in common. In general, Arctiidae, Noctuidae, Pyralidae and Sphingidae dominated both the sites. The Moths were collected by using mercury light traps (160 W). The moth diversity has been studied for the first time from Agricultural field of Western Maharashtra region.
Caderno de resumos - PROGRAMAS E PROJETOS
Authors: Autores Vários
Published: February 2024

Caderno de resumos - PROGRAMAS E PROJETOS
UJARAN KEBENCIAN NETIZEN INDONESIA PADA AKUN TWITTER ES TEH: TINJAUAN LINGUISTIK FORENSIK
Authors: Syafruddin  , Thaba Aziz , Ananda Refisa
Published: February 2024

This study aims to describe the form of netizens' hate speech on the @esteh_indonesia Twitter account which can be categorized as a violation of the law. This research is included in the qualitative research used to describe netizens' hate speech in @esteh_indonesia Twitter comments using forensic linguistic reviews. The methods and techniques used are the listening method and the note-taking technique. Listening is done by observing the hate speech of netizens on the Twitter account @esteh_indonesia. After that, the data that has been selected purposively is copied and then analyzed by collecting data that has been recorded in one folder, classifying and analyzing the data based on the form of hate speech with the guidelines of the Police circular regarding hate speech on social media. The results of the study prove that there are five forms of netizens' hate speech in the Twitter comments of the @esteh.indonesia account: 1) insults, 2) defamation, 3) blasphemy, 4) provoking, and 5) hoax. The results of this study can increase public awareness about the existence of hate speech on social media platforms, especially Twitter. This can encourage people to be more careful in interacting online.
“SOY NEGRA, SOY AFRO”: VIVENCIAS DE AUTORRECONOCIMIENTO DE LA MUJER AFRODESCENDIENTE EN HATONUEVO, LA GUAJIRA
Authors: Duarte Orozco Mario Alejandro , Guerra Oneida , Machado Ortiz María M´ónica
Published: February 2024

El objetivo fue analizar las vivencias y experiencias de autorreconocimiento de mujeres afrodescendientes. Además este artículo es de carácter investigativo, de tipo cualitativo, bajo el método biográfico-narrativo a partir de historias de vida de mujeres afrodescendientes en el contexto del municipio. Los resultados que se obtuvieron a través de las categorías, vivencias, experiencias y autorreconocimiento, dan cuenta que sus  historias y prácticas culturales han sido fragmentadas por procesos  como el desplazamiento forzado  por la minería en la zona, de igual manera se reafirma la invisibilidad interseccional, y  la  resignificación de lo negro y del cabello de las mujeres afrodescendientes entrevistadas. En conclusión, las vivencias y experiencias de autorreconocimiento reivindican y visibilizan la historia de origen, lo que a su vez dota de sentido de ser, de pertenencia.
Ethnoliteracy as a decolonial pedagogical approach to strengthen the cultural identity of fifth grade students of the Chaguaipe Educational Center of the Resguardo Indígena de Ipiales.
Authors: Ramírez Aristizábal Beatriz , Diaz Jojoa Natalia Fernanda , Ramírez Solarte Patricia del Socorro , Solarte Bravo Adriana Elizabeth
Published: February 2024

La etnoliteratura recoge las narraciones étnicas de las tradiciones, hechos y acontecimientos culturales que permite trasmitir la cosmovisión indígena y afianzar la identidad. En tal sentido el presente artículo desarrolla los resultados de la investigación “Etnoliteratura como apuesta pedagógica decolonial para el fortalecimiento de la identidad cultural de los estudiantes de grado quinto del Centro Educativo Chaguaipe”. Para ello, se utilizó el enfoque de investigación cualitativo, desde la etnografía, con el fin de develar las prácticas claves que preservan la identidad. Los resultados muestran que la pervivencia de la cultura se genera desde las prácticas etnoliterarias en la escuela y familia, las memorias de saberes y costumbres, todas ellas a través de la tradición oral como acción pedagógica decolonial; lo que permitió concluir que dichos actos pedagógicos desde las narraciones étnicas, permiten que la cosmovisión indígena re-exista en las memorias colectivas y afiance la identidad cultural en las nuevas generaciones.
Learning Ecosystem in Virtual Education. A Theoretical Contribution For the University Context
Authors: Gómez Valderrama Carlos Luis
Published: February 2024

El objetivo de la investigación fue estructurar un aporte teórico sobre el ecosistema de aprendizaje en educación virtual en el contexto universitario de la Universidad Pedagógica Experimental Libertador (UPEL) - Instituto de Mejoramiento Profesional del Magisterio (IMPM). Metodológicamente, se enmarca en el paradigma interpretativo bajo un enfoque cualitativo con un método fenomenológico. Los informantes clave lo conforman ocho estudiantes y ocho docentes, se utilizó la entrevista semiestructurada para la recolección de los datos. En los resultados se obtuvo que un rasgo característico de los eco-sistemas de aprendizaje en desarrollo es su capacidad de autoorganización, se distingue por su constante adaptación o desarrollo evolutivo tanto de los mecanismos dinámicos de aprendizaje y los mecanismos dinámicos de enseñanza. Estos parecieran que están separados de alguna manera pero son interdependientes en la educación virtual. Se concluye que el ecosistema de aprendizaje se autorregula,en ese sentido, las poblaciones de sus componentes vivos crecen o se reducen debido a decisiones estratégicas que se toman en línea con la visión y misión de la organización
Experiencias maritales en la etapa del nido vacío
Authors: Cabrera-García Victoria Eugenia , Morales-Acevedo Cheryl Andrea , Guarín Ortega Irma Beatriz
Published: February 2024

At the beginning of their marital relationship, couples experience high levels of satisfaction; however, due to the dedication required for raising children and professional occupations, this can take a back seat, leading to a decline in satisfaction over the years. This study aimed to analyze the experiences of marital satisfaction during the empty-nest stage among Colombian couples. Initially, a quantitative methodology was used, followed by a second qualitative phase with a phenomenological tradition, employing dialogic, participatory, and contextualized strategies. A total of 17 participants were involved: 9 women and 8 men. The results describe the discursive orders regarding how some marriages reach this stage with high or low levels of marital satisfaction. Both satisfied and dissatisfied individuals rarely express affection and admiration verbally, generally doing so through actions; dissatisfied men wish their wives would seek their attention, but their wives do not, and they believe their children were the focus of their aspirations, making it seem pointless to continue together. Dissatisfied women see the empty nest as an opportunity to focus on themselves, now that the children are no longer present, and believe that both partners must "win" in an argument. Satisfied men and women have, over the years, learned to calm themselves during conflicts, and in this stage, they are more accepting of their wives' influence. The study concludes that this stage of the life cycle entails several adjustments and learnings in marital relationships. In satisfied couples, there is a predominant sense of valuing and caring for each other more, as they face this new experience alone together. In dissatisfied couples, the sense of being together remains important, though without a clear purpose, and they acknowledge having focused their marital life around their children, finding it challenging to reconnect as a couple during this stage. These findings offer a reflection on the marital experiences of men and women after many years of marriage, with the aim of guiding preventive actions that contribute to relationship stability in the Latin American context.
Mecanismos para prevenir la Corrupción
Authors: Ruiz-Acosta Liliana Elizabeth , Gomez Miranda Oscar Mauricio
Published: February 2024

El presente artículo analiza la gestión de los ministerios de Colombia durante el año 2016 para la reducción de la corrupción. El estudio se realizó mediante la revisión y comparación de las matrices de riesgos de corrupción elaboradas por 16 ministerios de Colombia durante los años 2016 y 2017, además, de los informes de auditoría de la Contraloría General de la República (CGR) de estas entidades, para la vigencia 2016. Para lograr el objetivo, se utilizó el software NVivo 12 Plus, con el cual se analizaron 773 procesos a través de 9 categorías. Se concluyó que las matrices de riesgos de corrupción podrían ser efectivas para prevenir la corrupción, sin embargo, no lo son en la práctica debido a diversas causas, entre las que se encuentran las diferencias que existen entre los resultados obtenidos en las matrices de riesgos de corrupción elaboradas por los ministerios y los hallazgos presentados por la CGR, que si bien no constituyen hechos de corrupción, representan insumos para adelantar procesos de responsabilidad fiscal.
Análisis descriptivo de los servicios posadopción a personas adultas en España
Authors: Jiménez-Luque Natalia , Sánchez-Sandoval Yolanda
Published: February 2024

La adopción es una medida de protección infantil que permite un cambio positivo en la vida de niños, niñas o adolescentes y  posibilita la creación de una nueva familia. Los procesos de adopción implican intervenciones profesionales de calidad durante años. Este trabajo analiza servicios posadopción en España que ofrecen atención a personas adultas adoptadas. Se pretende conocer las características sociodemográficas de los usuarios, las demandas que plantean y las respuestas ofrecidas desde estos servicios. Participan 38 servicios profesionales con competencia en adopción en España que cumplimentaron un cuestionario estructurado sobre información relativa al servicio. Los resultados muestran una mayor proporción de mujeres demandantes de servicios  posadopción (63.42%). El 24.18% fueron usuarios adoptados internacionalmente. La mayor demanda atendida es la solicitud de información sobre su familia biológica (al menos 65.79%). Desde los servicios ofrecen respuestas de asesoramiento relacionado con la adopción (84.8%), búsqueda de orígenes (84.8%) y terapia psicológica (63.6%), además de otros recursos no específicos para adultos adoptados. Las nuevas necesidades planteadas por adultos adoptados requieren conocer y fortalecer los servicios posadopción orientados a estos usuarios, insistiendo en el trabajo en red de la adopción y en mejorar las competencias en adopción de los profesionales.
Sustainable Enterprise Risk Management Paradigm for Enhancing Nigeria’s Road Transport Sector Performance
Authors:   SEAD Research Group Glasgow Caledonian University London Campus, London United Kingdom, Kareem Akintoye Kareem
Published: February 2024

This paper proposes the development of a Sustainable Enterprise Risk Management (SERM) as a paradigm for enhancing transportation agency’s performance in the Global South (GS) with a focus on the Nigerian Road Transport Sector. Sustainable transport has a key part to play in fostering sustainable economic growth and expanding access to essential services as a vital driver of economic and social development. However, transport sector faces an evolving landscape of sustainability (ESG) risks that can impact their success and even survival. It has been evidenced that current risk management practices are not adequately addressing sustainability risks. Preliminary findings have shown various organisational/institutional challenges in the Nigerian Transport sector driving the breakdown in sustainable ERM. Literature has established that organizational resilience starts at the top with the use of ERM paradigm to achieve good risk governance and organisational objective in normal, volatile and crisis situations. However, there have been a very limited literature regarding alignment of ERM with transportation sector. This paper explores Systems Thinking/Systems Dynamics (ST/SD), Transport specific ERM frameworks in the GN and the two dominant ERM frameworks with a view of adapting their standards and articulating the practices in the Global North (GN) to develop implementation guidance that could enhance the Nigeria road transport sector performance with reduced risk. It aims to provide a better understanding to help policy makers with decision making on sustainable Transportation. Keywords: Enterprise Risk Management (ERM), Global North (GN), Global South (GS), Sustainability Concept, Sustainable Transportation, Systems Thinking/Systems Dynamics (ST/ SD). Proceedings Citation Format Abraham Rasheed Adeyemi (2023): Sustainable Energy Planning and Modelling for Global South: A Case Study of the Federal Republic of Nigeria. Proceedings of the 37th iSTEAMS Multidisciplinary Cross-Border Conference. 30th October – 1st November, 2023. Academic City University College, Accra, Ghana. Pp 107-140. dx.doi.org/10.22624/AIMS/ACCRACROSSBORDER2023 V2P9
Oddziaływanie HM Głogów na efektywność produkcyjną i ekonomiczną gospodarstw rolnych
Authors: Nietupski Teodor , Paczkowski Lech
Published: February 2024

Analizę przeprowadzono na danych zebranych z ponad 100 zbadanych gospodarstw rolnych w okresie obejmującym lata 1995-1997. Badania dotyczą gospodarstw położonych na terenie objętym oddziaływaniem Huty Miedzi „Głogów”. Autorzy dokonali próby oceny wpływu pracy huty na organizację i wyniki finansowe badanych gospodarstw w warunkach zmniejszania się zanieczyszczeń. Badane gospodarstwa podzielono na grupy ze względu na: * powierzchnię użytków rolnych (3-7 ha, 7-10 ha, powyżej 10 ha); * lokalizacja gospodarstw ze względu na emitenta: gospodarstwa położone w strefie zanieczyszczonej; * odległość od O do 5 km (strefa 1) i * te w strefie bezpośredniego oddziaływania - odległość od 5 do 12 km (strefa 2). Badania wykazały, że warunki środowiskowe na terenie wokół huty uległy znacznej poprawie. Stwierdzono także, że różnice w organizacji gospodarstw były nieistotne. W obu strefach dominowały zboża (70%) i rośliny okopowe (ok. 25%), jednak liczebność zwierząt gospodarskich i intensywność organizacji były tu niewielkie. Plony roślin uprawnych i podstawowe kategorie produkcji osiągnęły wyższy poziom w strefie 2, natomiast zysk był podobny w obu strefach. Na sytuację finansową gospodarstw położonych w pobliżu huty miedzi duży wpływ miały dochody niezwiązane z pracą rolnika – uzyskiwane były z zatrudnienia w przemyśle. W strefie 1 źródłem dochodów były wypłaty odszkodowań. Generalnie badania prowadzą do wniosku, że wpływ Huty Miedzi „Głogów” na wyniki finansowe i produkcyjne jest bardzo ograniczony. (tłumaczenie - LW).
Potentially toxic elements in grapevine varieties and soil in Serbia
Authors: Milicevic Tijana , Relic Dubravka , Tomkovic Jelena , Malicanin Marko , Skrivanj Sandra , Anicic-Urosevic Mira , Popovic Aleksandar
Published: February 2024

The accumulation of potentially toxic elements (PTEs) in agricultural soils
and their subsequent uptake by plants, posing risks to agricultural products
and con?sumers is of particular concern for investigation. Vineyard soils
are especially vulnerable to pollution from various sources, including
agrochemicals, fertilizers and surrounding polluting activities. This
research is based on the BCR sequential extraction method to assess PTE
speciation in vineyard soil samples. Additionally, it investigates the
bioaccumulation of PTEs in grapevines (Cabernet sauvignon and Sauvignon
blanc) and evaluates potential health risks for consumers of grapevine
products based on each investigated PTE. The find?ings reveal that certain
PTEs, Cd, Mn, Ba, Co, Pb and Cu exhibit significant mobility and
bioavailability in vineyard soils, emphasizing the importance of continuous
monitoring for food safety. The bioaccumulation potential, based on
calculated biological accumulation concentration (BAC), exists for some
elements, especially for Cu and Zn from easily avail?able soil phase. The
human health risk assessment indicates that the consumption of grape?vine
products poses minimal risk (HQ < 1) to consumers. Anyhow, among the
investigated PTEs, Ba and Cu have the highest HQs. This research contributes
to a better understanding of PTE dynamics in vineyard environments,
emphasizing the need for ongoing monitoring and control measures to ensure
agricultural product safety and protect consumers? health.
Multiomics Analyses Identify AKR1A1 as a Biomarker for Diabetic Kidney Disease
Authors: Li DengFeng , Hsu Fang-Chi , Palmer Nicholette D. , Liu Liang , Choi Young A. , Murea Mariana , Parks John S. , Bowden Donald W. , Freedman Barry I. , Ma Lijun
Published: February 2024

Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease. Because many genes associate with DKD, multiomics approaches were used to narrow the list of functional genes, gene products, and related pathways providing insights into the pathophysiological mechanisms of DKD. The Kidney Precision Medicine Project human kidney single-cell RNA-sequencing (scRNA-seq) data set and Mendeley Data on human kidney cortex biopsy proteomics were used. The R package Seurat was used to analyze scRNA-seq data and data from a subset of proximal tubule cells. PathfindR was applied for pathway analysis in cell type–specific differentially expressed genes and the R limma package was used to analyze differential protein expression in kidney cortex. A total of 790 differentially expressed genes were identified in proximal tubule cells, including 530 upregulated and 260 downregulated transcripts. Compared with differentially expressed proteins, 24 genes or proteins were in common. An integrated analysis combining protein quantitative trait loci, genome-wide association study hits (namely, estimated glomerular filtration rate), and a plasma metabolomics analysis was performed using baseline metabolites predictive of DKD progression in our longitudinal Diabetes Heart Study samples. The aldo-keto reductase family 1 member A1 gene (AKR1A1) was revealed as a potential molecular hub for DKD cellular dysfunction in several cross-linked pathways featured by deficiency of this enzyme.

Article Highlights
Estimating Glycemia From HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy
Authors: Tozzo Veronica , Genco Matthew , Omololu Shammah O. , Mow Christopher , Patel Hasmukh R. , Patel Chhaya H. , Ho Samantha N. , Lam Evie , Abdulsater Batoul , Patel Nikita , Cohen Robert M. , Nathan David M. , Powe Camille E. , Wexler Deborah J. , Higgins John M.
Published: February 2024

OBJECTIVE

To examine the accuracy of different periods of continuous glucose monitoring (CGM), hemoglobin A1c (HbA1c), and their combination for estimating mean glycemia over 90 days (AG90).

RESEARCH DESIGN AND METHODS

We retrospectively studied 985 CGM periods of 90 days with <10% missing data from 315 adults (86% of whom had type 1 diabetes) with paired HbA1c measurements. The impact of mean red blood cell age as a proxy for nonglycemic effects on HbA1c was estimated using published theoretical models and in comparison with empirical data. Given the lack of a gold standard measurement for AG90, we applied correction methods to generate a reference (eAG90) that we used to assess accuracy for HbA1c and CGM.

RESULTS

Using 14 days of CGM at the end of the 90-day period resulted in a mean absolute error (95th percentile) of 14 (34) mg/dL when compared with eAG90. Nonglycemic effects on HbA1c led to a mean absolute error for average glucose calculated from HbA1c of 12 (29) mg/dL. Combining 14 days of CGM with HbA1c reduced the error to 10 (26) mg/dL. Mismatches between CGM and HbA1c >40 mg/dL occurred more than 5% of the time.

CONCLUSIONS

The accuracy of estimates of eAG90 from limited periods of CGM can be improved by averaging with an HbA1c-based estimate or extending the monitoring period beyond ∼26 days. Large mismatches between eAG90 estimated from CGM and HbA1c are not unusual and may persist due to stable nonglycemic factors.
A Diabetes Pregnancy Technology Roadmap: The 2023 Norbert Freinkel Award Lecture
Authors: Murphy Helen R.
Published: February 2024

Norbert Freinkel emphasized the need for “more aggressive therapy with exogenous insulin” during type 1 diabetes (T1D) pregnancy. Recent advances in diabetes technology, continuous glucose monitoring (CGM), and hybrid closed-loop (HCL) insulin delivery systems allow us to revisit Freinkel’s observations from a contemporary perspective. The Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial (CONCEPTT) led to international recommendations that CGM be offered to all pregnant women with T1D to help them meet their pregnancy glucose targets and improve neonatal outcomes. However, despite CGM use, only 35% of trial participants reached the pregnancy glucose targets by 35 weeks’ gestation, which is too late for optimal obstetric and neonatal outcomes. The constant vigilance to CGM data and insulin dose adjustment, with perpetual worry about the impact of hyperglycemia on the developing fetal structures, leave many pregnant women feeling overwhelmed. HCL systems that can adapt to marked gestational changes in insulin sensitivity and pharmacokinetics may help to bridge the gap between the nonpregnant time in range glycemic targets (70–180 mg/dL) and the substantially more stringent pregnancy-specific targets (TIRp) (63–140 mg/dL) required for optimal obstetric and neonatal outcomes. Use of HCL (CamAPS FX system) was associated with a 10.5% higher TIRp, 10.2% less hyperglycemia, and 12.3% higher overnight TIRp. Clinical benefits were accompanied by 3.7 kg (8 lb) less gestational weight gain and consistently achieved across a representative patient population of insulin pump or injection users, across trial sites, and across maternal HbA1c categories. Working collaboratively, women, HCL technology, and health care teams achieved improved glycemia with less worry, less work, and more positive pregnancy experiences.
TRIB2-mediated modulation of AMPK promotes hepatic insulin resistance
Authors: Wang Dan , Kang Xiaonan , Zhang Lu , Guo Yaoyao , Zhang Ziyin , Ren Huihui , Yuan Gang
Published: February 2024

Insulin resistance and its linked health complications are increasing in prevalence. Recent work has caused the role of Tribbles2 (TRIB2) in metabolism and cellular signaling to be increasingly appreciated, but its role in the progression of insulin resistance has not been elucidated. Here, we explore the functions of TRIB2 in modulating insulin resistance and the mechanism involved in insulin resistance mice and palmitic acid (PA) treated HepG2 cells. We demonstrate that whole-body knockout and hepatic-specific TRIB2 deficiency protect against diet-induced insulin resistance, inflammation and ER stress. Accordingly, upregulation of TRIB2 in the liver aggravates these metabolic disturbances in HFD-induced mice and ob/ob mice. Mechanistically, TRIB2 directly binds to the αγ-SBS domain of PRKAB through its pseudokinase domain, subsequently inhibiting the formation and activity of the AMPK complex. Moreover, the results of intervention against AMPK suggest that the effects of TRIB2 depend on AMPK. Our findings reveal that TRIB2 is a novel target for the treatment of insulin resistance and its associated metabolic complications and clarify the function of TRIB2 as a regulatory component of AMPK activity.
Stable fixation of an ultra-short femoral neck-preserving hip prosthesis: a 5-year RSA, DXA, and clinical prospective outcome study of 48 patients
Authors: Christiansen Janus D , Laursen Mogens , Blunn Gordon W , Nielsen Poul T
Published: February 2024

Background and purpose: We previously showed promising primary stability and preservation of bone stock with the ultra-short neck-loading hip implant in total hip arthroplasty (THA). The aim of this study was to evaluate clinical outcome, implant stability, and bone mineral density (BMD).Methods: 50 patients were treated with the ultra-short neck Primoris hip implant at baseline and 48 were available for evaluation at 5-year follow-up. 5 different patient-reported outcome measures (PROMs) including hip-specific scores, disease-specific and generic quality of life outcome measures, and an activity score were used. Furthermore, implant stability using radiostereometric analysis (RSA) and assessment of periprosthetic BMD using dual-energy X-ray absorptiometry (DXA) were applied.Results: By 1-year follow-up, all PROMs showed improvements and remained high at 5-year follow-up. After initial distal translation (subsidence) and negative rotation around the z-axis (varus tilt) the implant showed stable fixation at 5-year follow-up with no further migration beyond 12 months. In the regions of interest (ROI) 3 and 4, BMD remained stable. In ROI 2, further bone loss of 12% was found at 5-year follow-up.Conclusion: Clinical outcome including PROMs was satisfying throughout the 5-year follow-up period. The hip implant remains stable with both bone preservation and loss 5 years after surgery.
Sequência de atividades de leitura e análise linguística na perspectiva dialógica com o gênero discursivo apólógo
Authors: Oliveira Ecilia Braga de , Ohuschi Márcia Cristina Greco , Rodrigues Isabel Cristina França dos Santos
Published: February 2024

O objetivo deste trabalho é apresentar uma sequência de atividades de leitura e análise linguística em perspectiva dialógica com o apólogo “O toco de lápis”, para o 6º ano do Ensino Fundamental. As ações teórico-metodológicas partem dos estudos de Volóchinov (2021 [1929]; 2013[1930]), Bakhtin (2011 [1979]), Geraldi (2005[1984], 2013[1991]), Franchi (1991 [1987]), Polato (2017), Menegassi (2020) e Xx e Autor  (2022). Pretende-se, assim, estabelecer um diálogo com o/a professor/a da educação básica sobre possibilidades do alargamento da consciência sociológica do estudante, contemplando habilidades de leitura e reflexão de elementos linguísticos em enunciados vivos e concretos.
Didática e planejamento de ensino na visão docente
Authors: Souza Maria Clara de Lima , Costa Ademárcia Lopes de Oliveira
Published: February 2024

A didática é de suma importância na formação profissional docente, uma vez que, engloba os elementos didáticos que resultam nos processos de ensino e de aprendizagem. Desse modo, a boa elaboração do planejamento, elemento que faz parte da didática, é fundamental para a prática educativa porque é através desse documento que o professor aborda o que será realizado em sala de aula, sendo necessário, escolher os objetivos, conteúdos, metodologias, recursos e avaliações. Nesse contexto, se insere o presente estudo, cujo objetivo é analisar as concepções de um docente sobre os temas didática, planejamento e avaliação. Trata-se de uma pesquisa qualitativa, descritiva, com o uso da revisão bibliográfica e da pesquisa de campo, por meio de um questionário, realizado com um(a) professor(a) que atua no Ensino Fundamental e no Ensino Médio, na área de Ciências Biológicas. Os resultados evidenciam que a pessoa participante conhece os conceitos da Didática e suas ferramentas, mas as dificuldades estruturais na escola podem prejudicar o bom desenvolvimento da prática educativa. Portanto, diante das respostas obtidas no questionário é notório que o processo do seu trabalho está sempre voltado no aluno para atender as necessidades da realidade que ele vive, desde a elaboração do planejamento com a escolha de conteúdos e métodos até a prática de ensinar a fim de desenvolver um ser cognitivo, crítico, realista e reflexivo sobre o mundo que o cerca.
A outremização do sujeito colonial em Danticat e Kincaid
Authors: Nunes Anna Júlia Targino de Castro , Sá Nicole Anizio Mariano de , Mendes Maria Elizabeth Peregrino Souto Maior
Published: February 2024

O objetivo da presente pesquisa é investigar a experiência diaspórica dos sujeitos femininos representados na novela Lucy, de Jamaica Kincaid e no conto “Children of the Sea”, de Edwidge Danticat. Compartilhando origens afro-caribenhas, sendo Kincaid de Antígua e Barbuda, e Dandicat do Haiti, as escritoras problematizam em sua oeuvre os processos diaspóricos dos sujeitos colonizados, suas experiências enquanto seres humanos marcados por traços étnicos, papéis sociais específicos e determinadas expectativas culturais. A novela Lucy de Kincaid e o conto “Children of the Sea” de Danticat, explicitam as motivações políticas dos sujeitos migrantes em uma jornada rumo à liberdade, e debatem as dificuldades dos corpos marcados pela herança colonial de terem seus direitos humanos assegurados em um país que as enxerga apenas como cidadãs de segunda classe. Assim, pretende-se analisar os modos através dos quais as vivências das personagens Lucy e Célianne são afetadas por sua identidade enquanto mulheres negras colonizadas. As duas narrativas expõem não apenas os efeitos deletérios do colonialismo, como também a outremização e a subalternização do corpo negro, e principalmente como ele reage aos processos de marginalização e desumanização a que são submetidos. Como fundamentação teórica, a análise proposta se apoia nos estudos de Davis (1981), Lorde (1984), Crenshaw (1991), Vergès (2018) e Morrison (2019), com o intuito de demonstrar, através de uma ótica comparada, os modos através dos quais a experiência do passado colonial afeta o corpo feminino, que carrega consigo estigmas, traumas e marcas de opressão agravadas por fatores como gênero, raça e classe. Tanto a personagem Lucy quanto Célianne sofrem um processo de subalternização triplo, enquanto mulheres, negras e migrantes. Embora os olhares de inferioridade sobre esse sujeito tentem limitar seus lugares de atuação, em ambos os casos as personagens resistem e revidam às tentativas de silenciamento e apagamento que sofrem.
Florentina Esteves e Orlanda Amarílis em diálogo
Authors: Silva Angela Glaucia da , Silva Ezilda Maciel da
Published: February 2024

Este artigo apresenta uma proposta didática decolonial para o ensino dos contos: “Que Jiquitaia!”, de Florentina Esteves (1990), e “Desencanto”, de Orlanda Amarílis (1991). A concepção adotada é a de Iris Amâncio e Miriam Jorge (2008). Deste modo, o objetivo é propor uma prática de ensino transgressiva, humanizadora e transformadora por meio do qual os discentes se apropriem da “literatura enquanto literatura”. A metodologia fundamenta-se no estudo bibliográfico. A conclusão indica que ensinar, aprender, analisar e interpretar os contos de Esteves e Amarílis, no âmbito escolar, possibilita que os alunos pratiquem a leitura literária como um ato humanizador, emancipador e polifônico da/na literatura acreana e cabo-verdiana.
Time delay and nonlinear incidence effects on the stochastic SIRC epidemic model
Authors:   Research Center STIS, M2CS, Department of Applied Mathematics and Informatics, ENSAM, Mohammed V University, Ben Lahbib A. , Azrar L. ,   Research Center STIS, M2CS, Department of Applied Mathematics and Informatics, ENSAM, Mohammed V University
Published: February 2024

This paper presents theoretical and numerical study of a stochastic SIRC epidemic model with time delay and nonlinear incidence. The existence and uniqueness of a global positive solution is proved. The Lyapunov analysis method is used to obtain sufficient conditions for the existence of a stationary distribution and the disease extinction under certain assumptions. Numerical simulations are also elaborated for the considered stochastic model in order to corroborate the theoretical findings.
DDFV scheme for nonlinear parabolic reaction-diffusion problems on general meshes
Authors:   Research Center STIS, M2CS, Department of Applied Mathematics and Informatics, ENSAM, Mohammed V University, Bazirha Z. , Azrar L. ,   Research Center STIS, M2CS, Department of Applied Mathematics and Informatics, ENSAM, Mohammed V University
Published: February 2024

This paper focuses on the nonlinear anisotropic parabolic model of the form ∂tC(u)−div(Λ∇u)+R(u)=f, where C, R, f, and Λ are respectively: two nonlinear functions, a source term and an anisotropic tensor diffusion. For space discretization, various types of the Discrete Duality Finite Volume (DDFV) scheme are elaborated leading to positive definite stiffness matrices for the diffusion term. A general mesh is used and hard anisotropic tensor with discontinuous effects is considered. An implicit time scheme is developed as well as the Newton–Raphson method to solve the resulting nonlinear system. An iterative incremental approach is elaborated handling the effects of anisotropy, discontinuity and non-linearity. The performance of the presented direct and indirect DDFV schemes for different meshes has been demonstrated by various numerical tests. A super-convergence in the discrete L2 and H1-norms is also demonstrated.
Dynamics of an ecological prey–predator model based on the generalized Hattaf fractional derivative
Authors:   Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M'Sick, Hassan II University of Casablanca, Assadiki F. , El Younoussi M. ,   Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M'Sick, Hassan II University of Casablanca, Hattaf K. ,   Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M'sik, Hassan II University of Casablanca, Casablanca, Morocco; Centre Régional des Métiers de l'Education et de la Formation (CRMEF), Casablanca, Morocco, Yousfi N. ,   Laboratory of Analysis, Modeling and Simulation (LAMS), Faculty of Sciences Ben M'Sick, Hassan II University of Casablanca
Published: February 2024

In this paper, we propose and analyze a fractional prey–predator model with generalized Hattaf fractional (GHF) derivative. We prove that our proposed model is ecologically and mathematically well-posed. Furthermore, we show that our model has three equilibrium points. Finally, we establish the stability of these equilibria.
To the definition of the concept of «public formation»
Authors: Ustymenko O. A.
Published: February 2024

The article is devoted to the legal nature of public formation and the problem of determining the appropriate definition. The essence of public formation as an independent institution of public society is analyzed. A comparison and comparison of the concepts «participant in civil relations» and «public formation» was carried out. The definition of public formation and types of public formations given in the sectoral regulatory legal act: the Law of Ukraine «On State Registration of Legal Entities, Individual Entrepreneurs and Public Formations» – political parties, public associations, professional unions and their associations – is characterized, creative unions, permanent arbitration courts, employers’ organizations and their associations, separate divisions of foreign non-governmental organizations, representative offices, branches of foreign charitable organizations. A conclusion was drawn on the division of public formations into those that have the status of a legal entity, and public formations that do not have the status of a legal entity. It is noted that there are such terms synonymous by their legal nature in the field of accounting of public entities as «state registration», «legalization» and «accreditation». The information on the types of public formations that must be entered into the Unified register of public formations – an electronic database containing information on the relevant legalization (registration) – has been analyzed. Attention is focused on the fact that we are talking about political parties; NGOs; trade unions, trade union organizations; employers’ organizations, associations of employers’ organizations; all-Ukrainian, local associations of credit unions; charitable organizations: all-Ukrainian, international, local charitable organizations, branches, branches, representative offices of all-Ukrainian, international charitable organizations; creative unions; Chambers of Commerce and Industry: Chamber of Commerce and Industry of Ukraine, Chamber of Commerce and Industry of the Autonomous Republic of Crimea, regional Chambers of Commerce and Industry; permanent arbitration courts; associations of local self-government bodies. Since the current national legislation does not contain a definition of public formation, based on the results of the research, such a definition of public formation is proposed as an organization that is created and functions in order to satisfy various public rights and interests.