bluuebunny/crossref_metadata_2025 huggingface dataset:
Гемостаз та запалення у пацієнтів із політравмою
Authors: Filyk O.V. , Vyshynska M.B.
Published: December 2021

Актуальність. Причинами смерті при тяжких травмах є як ушкодження, несумісні з життям, так і тяжкі кровотечі. Коагулопатію, асоційовану з травмою, виявляють у 46 % пацієнтів уже на місці події та у 60 % пацієнтів — при надходженні на лікування. Мета: встановити наявність зв’язку між показниками загальної відповіді організму на запалення та показниками судинно-тромбоцитарного і коагуляційного гемостазу у пацієнтів з політравмою. Матеріали та методи. Проведено проспективне обсерваційне дослідження 20 пацієнтів віком від 19 до 55 років з політравмою, які перебували на лікуванні у відділенні анестезіології з ліжками інтенсивної терапії в Комунальному некомерційному підприємстві «8-ма міська клінічна лікарня м. Львова». Пацієнтів оцінювали за Injury Severity Score (ISS) та шкалою APACHE II (Acute Physiology And Chronic Health Evaluation II) з урахуванням тривалості синдрому загальної відповіді організму на запалення і лікування у відділенні інтенсивної терапії (ВІТ) та госпіталізації. Етапи дослідження: надходження на лікування у ВІТ (d1), третя доба (d3), п’ята доба (d5). Основними оцінюваними клінічними маркерами були показники: загальної відповіді організму на запалення, судинно-тромбоцитарного гемостазу (внутрішньосудинна активація тромбоцитів, агрегація тромбоцитів, індукована адреналіном і аденозиндифосфатом), коагуляційного гемостазу (міжнародне нормалізоване відношення, активований частковий тромбопластиновий час, рівень загального фібриногену та D-димерів). Результати. Встановлено наявність вірогідного (p < 0,05) позитивного кореляційного зв’язку між співвідношенням рівнів дискоехіноцитів до сфероехіноцитів та рівнем загального фібриногену на етапі d1, а також тенденцію (p = 0,09) до наявності позитивного кореляційного зв’язку між цим співвідношенням та температурою тіла пацієнта. Виявлено вірогідний (p < 0,05) зворотний кореляційний зв’язок між цим співвідношенням і рівнем тяжкості стану пацієнтів за шкалою APACHE II та прямий вірогідний (p < 0,05) кореляційний зв’язок із тривалістю госпіталізації у ВІТ, а також тенденції до зворотного кореляційного зв’язку з тяжкістю ушкоджень за шкалою ISS (p = 0,07) та до прямого кореляційного внаслідок Systemic Inflammatory Response Syndrome (SIRS) (p = 0,12). Висновки. У пацієнтів із політравмою встановлено: наявність вірогідного (p < 0,05) позитивного кореляційного зв’язку між співвідношенням дискоехіноцити/сфероехіноцити та рівнем загального фібриногену; тенденцію (p = 0,09) до позитивного кореляційного зв’язку між цим співвідношенням та температурою тіла пацієнта; вірогідний (p < 0,05) зворотний кореляційний зв’язок з рівнем тяжкості стану пацієнтів за шкалою APACHE II; прямий вірогідний (p < 0,05) кореляційний зв’язок з тривалістю госпіталізації у ВІТ; тенденцію (p = 0,07) до зворотного кореляційного зв’язку з тяжкістю ушкоджень за шкалою ISS та тенденцію (p = 0,12) до прямого кореляційного зв’язку з тривалістю SIRS.
Артеріотрахеальна нориця як ускладнення пролонгованої трахеостомії
Authors: Sobko R.Yu. , Boiko M.T.
Published: December 2021

У статті наведений клінічний випадок рідкісного та тяжкого ускладнення пролонгованої трахеостомії у вигляді формування нориці між просвітом трахеї та брахіоцефальною артерією та розвитку масивної кровотечі з неї. Лікування пацієнта було ургентним й успішним. Пацієнту проведене оперативне втручання з наступним алопротезуванням плечоголовного стовбура (використаний судинний протез Vascutec 8 мм) та формуванням анастомозу методикою безперервного шва. На 17-ту післяопераційну добу пацієнта виписали додому в задовільному стані.
Застосування екстракорпоральних методів детоксикації для елімінації метотрексату
Authors: Sobko R.Yu. , Borachok T.T. , Oranskyi T.B. , Kovalov M.O. , Zapotochna Kh.M. , Fesenko U.A.
Published: December 2021

Описаний клінічний випадок 12-річної дитини з остеосаркомою лівої малогомілкової кістки, Т1N0M0G3, яка отримувала лікування високодозовим метотрексатом 12 г/м2. Внаслідок затримки елімінації метотрексату в дівчинки розвинулась гостра печінкова недостатність. У пацієнтки рівень АЛТ підвищувався до 4790 Од/л, АСТ — до 4320 Од/л, що свідчить про загрозливе для життя гостре ураження печінки. При цьому не відмічалися коагулопатія, значне підвищення рівня білірубіну та печінкова енцефалопатія. Повній картині гострої печінкової недостатності вдалося запобігти завдяки своєчасному застосуванню еферентної терапії. Пацієнтка отримувала внутрішньовенну гідратаційну терапію та олужнення сечі в об’ємі 3000 мл/м2/добу розчинами 5% глюкози в комбінації з 20 ммоль NaHCO3/л та 20 ммоль розчину KCl/л. При цьому діурез пацієнтки становив більше ніж 600 мл/м2/6 годин. Крім того, застосовувалась антидотна терапія кальцію фолінатом. У даному випадку ми використали тривалу вено-венозну гемодіафільтрацію апаратом Prismaflex. Після першого проведеного сеансу, що тривав протягом 78 годин, відмічалось повторне зростання концентрації метотрексату в крові та збільшення рівнів АЛТ, АСТ, що свідчить про великий об’єм розподілу метотрексату та потребу в тривалій терапії екстракорпоральними методами. Тому сеанс тривалої вено-венозної гемодіафільтрації був продовжений. Після ще 78 годин проведення тривалої вено-венозної гемодіафільтрації відмічались відсутність повторного зростання показників рівня метотрексату в крові та нормалізація рівнів трансаміназ та загального білірубіну. Додатково в пацієнтки були досліджені рівень гомоцистеїну на предмет гіпергомоцистеїнемії, а також 4 гени, які також визначають схильність до гіпергомоцистеїнемії, — метилентетрагідрофолат редуктаза MTHFR C677T, A1298C, метіонін синтетаза MTRR та MTR. Підвищений рівень гомоцистеїну, а також гетерозиготність даних генів свідчать про сповільнення виведення метотрексату або про повну затримку його виведення. У даному випадку результати даних досліджень були негативними. Висновки. Даний клінічний випадок свідчить про ефективність застосування тривалої вено-венозної гемодіафільтрації в комбінації з внутрішньовенною гідратацією, олужненням сечі та антидотною терапією при токсичному впливі на печінку високодозового метотрексату на тлі уповільненої екскреції.
Mezquite: una planta alergénica de relevancia clínica en México
Authors: Batista-Roche Lino Gerardo , Huerta-Ocampo José Ángel
Published: December 2021

El mezquite es una planta del género Prosopis que se distribuye en áreas desérticas y semidesérticas de México. Su papel ecológico destaca por su capacidad de fijar nitrógeno y de fertilizar los suelos. Las semillas se usan para la alimentación animal y humana debido a sus propiedades nutricionales. Los extractos del mezquite se emplean en la medicina tradicional y farmacológica para el tratamiento de enfermedades crónicas como la diabetes. Sin embargo, la relevancia clínica del mezquite se le atribuye al polen, por la reacción alérgica que causa en las personas principalmente de las zonas desérticas de México. Las condiciones ambientales y atmosféricas influyen en su dispersión y al depositarse en la superficie del polen partículas asociadas a la contaminación ambiental, se incrementa su capacidad alergénica. Aunque varias proteínas alergénicas del polen del mezquite se han inmunodetectado, aún son muy pocas las identificadas, lo que limita el diseño de nuevas estrategias diagnósticas y terapéuticas. Por lo anterior, el objetivo de esta revisión es presentar lo que se conoce sobre la planta mediante una búsqueda bibliográfica en PubMed y Google Académico de artículos publicados a partir de los años 2000 al 2021, y fuentes relevantes más antiguas que hacen énfasis en la propiedad alergénica  del polen del mezquite, y fundamentar la influencia de la contaminación y el cambio climático en la alergenicidad de este polen en México,así como destacar la importancia de identificar las proteínas alergénicas que permitan implementar un diagnóstico y una inmunoterapia alérgeno-específica.
Características epidemiológicas, radiológicas e histológicas de cáncer de mama en usuarias de un hospital general regional en Guerrero, México
Authors: Solano Piza Reyna Isabel , Joanico Morales Baltazar , Candelario Cruz Rosalío , Sierra López Laura , Salgado Jiménez María de los Ángeles , Rodríguez Echeverría Gabriela
Published: December 2021

Objetivo: estimar la frecuencia y describir las características epidemiológicas, radiológicas e histopatológicas de mujeres con cáncer de mama. Métodos: estudio transversal en 2560 mujeres mayores de 25 años que acudieron a toma de mastografía durante el año 2018. Se describió la clasificación de bi-rads. Se revisaron los expedientes clínicos de las pacientes positivas a cáncer y se recabó información que incluía características epidemiológicas, resultado de estudio de mastografía e histopatológico. Los datos obtenidos fueron analizados en el programa Excel, se estudiaron las frecuencias y los porcentajes. Resultados: la frecuencia de cáncer de mama fue de 2.65% (68/2560). 60% tenía de 50 a 69 años de edad, 59%, obesidad y 47%, antecedente familiar de cáncer de mama. De acuerdo con la clasificación bi-rads, 3% fue B3, 45% fue B4, 49%, B5 y 3%, B6. Respecto al reporte histopatológico, 83% correspondió a carcinoma ductal infiltrante. Conclusiones: en pacientes con cáncer de mama, la edad de 50 a 69 años, la obesidad y el antecedente familiar de cáncer de mama fueron las características más frecuentes. Los estadios de bi-rads 4, 5 y 6 y el carcinoma ductal infiltrante fueron descritos con mayor frecuencia.
Implicaciones de la capacidad funcional en la funcionalidad familiar de las personas con artritis reumatoide
Authors: López Pérez Dulce Corazón de María , Morales Álvarez Clara T. , Álvarez Aguirre Alicia
Published: December 2021

La artritis reumatoide representa una pérdida de la capacidad funcional con gran potencial discapacitante, repercute en la salud mental, física y tiene una posible afectación en la funcionalidad familiar. En este trabajo se aborda el impacto que tiene esta enfermedad en el individuo y en el funcionamiento de la familia, así como sus implicaciones en el campo de la atención primaria.
Direito de propriedade: análise da política pública fundiária na Cidade Olímpica, em São Luís (MA)
Authors: Silva Ângela Maria Pinheiro da , Castro Cláudio Eduardo de
Published: December 2021

São Luís, assim como outras cidades do país, passou por intenso processo de urbanização entre 1950 e 1980, caracterizado pela forma acelerada e sem planejamento com que ocorreu, resultando na ocupação espraiada e dispersa em áreas periféricas, causando uma série de problemas sociais, ambientais, jurídicos e urbanísticos. Com o elevado número de habitações irregulares e a precariedade habitacional nos espaços urbanos, foi regulamentado no Brasil o direito à moradia digna e às políticas de regularização fundiária, que se consolidaram como políticas públicas a partir de 1980. A abordagem desta pesquisa consiste na análise relativa ao direito de propriedade, baseada na ocupação da Cidade Olímpica, na capital maranhense. O enfoque recai na emissão de títulos de propriedade privada no referido bairro, por meio do Programa de Regularização Fundiária Urbana em São Luís, com a ressalva de que a regularização fundiária não se limita à transferência de títulos fundiários. Para que ocorra de forma plena, esta deve estar articulada à regularização urbanística.
ANALISIS PERANCANGAN INVENTARIS BARANG PADA SEKOLAH MENENGAH KEJURUAN PERTANIAN PEMBANGUNAN (SMK-PP) NEGERI KUPANG
Authors: Ndaumanu Ricky Imanuel
Published: December 2021

Dewasa ini perkembangan teknologi informasi semakin berkembang, hal ini sejalan dengan perkembangan komputer yang semakin hari semakin berkembang pesat. Teknologi dan informasi merupakan dua hal yang tidak dapat dipisahkan satu sama lain. Perkembangan teknologi komunikasi merupakan alternatif bagi suatu perusahaan untuk menunjang pengolahan informasi yang baik. Apabila pengolahan informasi tidak teratur dan tidak terkoordinasi dengan baik akan mengakibatkan kurangnya pengetahuan informasi secara tepat dan akurat. Manfaat perkembangan teknologi informasi saat ini belum sepenuhnya digunakan oleh setiap perusahaan swasta maupun instansi pemerintah, belum begitu memanfaatkan penggunaan sarana komputer sebagai media pengolah informasi. Pengontrolan terhadap inventaris barang sangat dibutuhkan sehingga barang masih layak pakai dan yang tidak terpakai lagi dapat di control dengan baik. Sistem yang digunakan dalam pendataan barang inventaris masih menggunakan manual (menggunakan buku besar), sehingga mengalami kesulitan dalam memberikan laporan kepada pimpinan tentang barang-barang yang ada pada setiap bagian unit kerja terhadap barang-barang yang terpakai maupun keadaan barang-barang yang masih layak dipakai. Sehingga demikian efisiensi dan efektifitas dalam melakukan pengontrolan terhadap barang-barang pada setiap bagian unit kerja dapat terlaksana dengan baik. oleh karena itu pengontrolan terhadap barang-barang inventaris dibutuhkan adanya suatu aplikasi pencatatan inventaris yang cepat, tepat dan akurat.Untuk memudahkan pelaksanaan pendataan barang-barang yang ada pada setiap unit kerja, maka mengingat program Microsoft Visual Basic 6.0 sebagai salah satu penghasil program termudah dan tercepat, sehingga mamudahkan pemrograman untuk berinteraksi dengan elemen untuk setiap bentuk pemrograman. Dari hasil implementasi sistem, disimpulkan bahwa dengan menggunaka Software ini dapat membantu proses pendataan inventaris barang-barang yang ada pada setiap unit kerja di SMK-PP Negeri Kupang.
Snowmelt rate and continuity determine the intra-annual variability and magnitude of streamflow in three alpine watersheds in the western U.S.
Authors: Chen Xiaohua , Tang Guoping , Chen Tao , Niu Xiangyu
Published: December 2021

In semiarid to arid regions of the western U. S., the availability and
variability of river flow are highly subject to shifts in snow
accumulation and ablation in alpine watersheds. This study aims to
examine how shifts in snowmelt rate (SMR) and snow continuity, an
indicator of the consistent existence of snow on the ground, affect
snow-driven streamflow dynamics in three alpine watersheds in the U.S.
Great Basin. To achieve this end, the coupled hydro-ecological
simulation system (CHESS) is used to simulate river flow dynamics and
multiple snow metrics are calculated to quantify the variation of
snowmelt rate and snow continuity, the latter of which is measured,
respectively, by snow persistence (SP), snow residence time (SRT) and
snow season length (SSL). Then, a new approach is proposed to partition
streamflow into snow-driven and rain-driven streamflow. The statistical
analyses indicate that the three alpine watersheds experienced a
downward trend in SP, SRT, SSL and SMR during the study period of
1990-2016 due to regional warming. As a result, the decrease in SMR and
the decline in snow continuity shifted the day of 25% and 50% of the
snow-driven cumulative discharge as well as peak discharge toward an
earlier occurrence. Besides, the magnitudes of snow-driven annual
streamflow, summer baseflow and peak discharge also decreased due to the
declined snow continuity and the reduced snowmelt rate. Overall, by
using multiple snow and flow metrics as well as by partitioning
streamflow into snow-driven and rain-driven flow via the newly proposed
approach, we found that snowmelt rate and snow continuity determine the
streamflow hydrographs and magnitudes in the three alpine watersheds.
This has important implications for water resource management in the
snow-dominated region facing future climate warming given that warming
can significantly affect snow dynamics in alpine watersheds in semiarid
to arid regions.
Effects of hydropeaking on drift, stranding and community composition of macroinvertebrates: a field experimental approach in three regulated Swiss rivers
Authors: Tonolla Diego , Dossi Florian , Kastenhofer Olivier , Doering Michael , Hauer Christoph , Graf Wolfram , Schülting Lisa
Published: December 2021

Hydropeaking operation leads to fluctuations in wetted area between base
and peak flow and increases discharge-related hydraulic forces (e.g.,
flow velocity). These processes promote macroinvertebrate drift and
stranding, often affecting benthic abundance and biomass. Our field
experimental study – conducted in three hydropeaking-regulated Swiss
rivers – aimed to quantify (i) the short-term effects of the combined
increase in flow amplitude and up-ramping rate based on
macroinvertebrate drift and stranding, as well as (ii) long-term effects
based on the established community composition. Hydropeaking led to
increased macroinvertebrate drift compared to base flow and to
unaffected residual flow reaches. Moreover, stranding of
macroinvertebrates was positively related to drift, especially during
the up-ramping phase. Flow velocity and up-ramping rate were identified
as major determinants for macroinvertebrate drift, while flow ratio and
down-ramping rate for stranding. Particularly high sensitivity towards
HP was found for Limnephilidae, whereas Heptageniidae seemed to be
resistant in respect to short and long-term hydropeaking effects. In the
long-term, hydropeaking did not considerably reduce benthic density of
most taxa, especially of some highly resistant and resilient taxa such
as Chironomidae and Baetidae, which dominated the community composition
even though they showed comparably high drift and stranding responses.
Therefore, we argue that high passive drift and/or stranding, especially
of individual-rich taxa, does not necessarily indicate strong
hydropeaking sensitivity. Finally, our results demonstrate the necessity
to consider the differences in river-specific morphological complexity
and hydropeaking intensity, since these factors strongly influence the
community composition and short-term drift and stranding response of
macroinvertebrates to hydropower pressure.
Diet overlap and feeding preference of Oreochromis niloticus (Linnaeus, 1758) versus two native cichlids of the upper Kabompo River, northwest of Zambia.
Authors: Jere Arthertone
Published: December 2021

Evaluating the food and feeding habits of fish is fundamental in
fisheries and conservation biology research. In this study, the diet of
exotic Oreochromis niloticus was compared with the 2 most abundant and
aquaculture preferred native cichlids of native species (Orochromis
macrochir and Coptodon rendalli) in the upper Kabompo River, Zambia. We
hypothesized that exotic and native cichlids would show no dietary niche
overlap. We analyzed the stomach contents of 114 specimens of the fishes
sampled. Fishes were grouped into 3 major feeding groups: microphages,
macrophages and carnivores, and omnivores. They were also grouped into
size classes of <50, 51−100, 101−150, and 151−302 mm total
length (TL). O. niloticus had a larger dietary niche than two native
species (71% and 22%, respectively). The dietary niche overlap between
O. niloticus and native C. rendalli species in size classes
<50 was significant (F (2, 45) = 0.084, p < 0.05).
Dietary niche overlap between the native O. macrochir species in size
class <50 mm was low (F (2, 33) = 2.13, p >
0.05), while as in size classes 51−100 mm and 101−150 mm was high (F (2,
35) = 0.27, p < 0.05) for C. rendalli. There was no clear
evidence of ontogenetic diet shift of native cichlids, with the
exception of O. macrochir, which showed ontogenetic diet shifts within
the 51−100 mm size class. The dietary overlap results indicate
interspecific competition between exotic O. niloticus and native O.
macrochir, which may have major impacts on food web structure in the
upper Kabompo River and may explain population decreases of some native
species.
Implication of social isolation on mental health during the Covid-19 pandemic: a look at its religious and spiritual coping
Authors: Gohar Amna , Carvalho Alonso Bezerra de , Brandão Carlos da Fonseca
Published: December 2021

China was the center of Covid-19 which rapidly spread out all over the world. The rapid outbreak of Covid-19 in Asian countries has severely affected psychological and social life of people. Which also has a great influence on religion and faith. Spiritual and religious copping is an effective approach for mental relaxation and belief on the creator specifically during the Covid-19 outbreak. The main purpose of this study is observing the situation of Asian countries existing literature on human psychology and social life further it also explores religious and spiritual coping during Covid-19. Different studies were retrieved from online sources. In which the published articles were classified according to three themes such as human psychology, religious and spiritual coping and social life during Covid-19. It is evident from the literature that covid-19 has a great influence on human psychology. Majority people suffered from anxiety and depression in these tough days of life. Also, most of the people suffered from fear, depression, stress, loneliness during lockdown which effects their social life. The positive point was found that religion and spirituality helping people to reduce their stress and create positivity in their life. Spirituality helps out people in mental relaxation at times of crisis and epidemic situations while religious copings and strong believe on creator reduce anxiety and depression.
The nature and accuracy of Instagram posts concerning marketed orthodontic products:
Authors: Alkadhimi Aslam , Al-Moghrabi Dalya , Fleming Padhraig S.
Published: December 2021

Objectives

To scrutinize claims contained within Instagram posts related to six popular marketed orthodontic products.

Materials and Methods

Three hundred publicly available Instagram posts were identified using the following Instagram hashtags: #carrieremotion, #damonbraces, #invisalign, #acceledent, #propelorthodontics, and #myobrace. Pilot coding was undertaken on a subset of claims (n = 50) and a coding guide was developed. The associated claims were categorized under 24 recognized themes and their accuracy assessed on a five-point scale.

Results

Of 1730 posts screened, 300 were included for analysis. The majority of posts were based on photographs (n = 244, 81.3%) with the remainder (n = 56, 18.7%) including videos. Half of the posts involved a picture of the product in isolation (n = 150, 50%), with clinical cases presented in a minority (n = 99, 33%). Overall, 472 claims were included with treatment duration being the most frequent theme (n = 125, 26.5%). In terms of accuracy, most of the claims were judged to be “false” (n = 283, 60%) with less than 2% considered “objectively true.”

Conclusions

Most of the claims relating to six popular marketed orthodontic products concerned treatment duration. The vast majority of these claims were not supported by evidence and were judged to be false. Efforts should be made to promote the provision of accurate orthodontic information and to verify marketing claims on social media platforms.
Pregnancy Outcomes in Young Women With Youth-Onset Type 2 Diabetes Followed in the TODAY Study
Authors:   TODAY Study Group, Marcus Marsha D. , Gandica Rachelle , El ghormli Laure , Higgins Janine , Tesfaldet Bereket , Koren Dorit , Macleish Sarah , Escaname Elia Nila , Weinstock Ruth S.
Published: December 2021

OBJECTIVE

To assess pregnancy outcomes in young women with youth-onset type 2 diabetes followed in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study.

RESEARCH DESIGN AND METHODS

Pregnancy information (outcome and any maternal or fetal complications) was obtained from the female participants by self-report. Additionally, medical records for the pregnancy and the child’s neonatal course were obtained with data abstracted into standardized forms.

RESULTS

Over a maximum of 15 years, 260 pregnancies were reported by 141 women (aged 21.5 ± 3.2 years, BMI 35.6 ± 7.2 kg/m2, and diabetes duration 8.1 ± 3.2 years). Contraception use prior to pregnancy was reported by 13.5% of the women. Complications were reported by 65% of the women during their pregnancy. Pregnancy loss was observed in 25.3% and preterm birth in 32.6% of pregnancies. HbA1c ≥8% was observed in 31.9% of the pregnancies, and 35% of the pregnancies were complicated by chronic hypertension. Nephropathy prior to pregnancy was observed in 25% of the women. In the offspring, 7.8% were classified as small for gestational age, 26.8% large for gestational age, and 17.9% in the macrosomic range.

CONCLUSIONS

Based on observations from the TODAY cohort, young women with pregestational, youth-onset type 2 diabetes had very high rates of maternal complications stemming from significant socioeconomic disadvantage. The substantial maternal and infant complications seen in these young moms could potentially be avoided with improved contraception rates and reproductive planning.
Lifestyle Changes and Long-term Weight Gain in Women With and Without a History of Gestational Diabetes Mellitus: A Prospective Study of 54,062 Women in the Nurses’ Health Study II
Authors: Yang Jiaxi , Zhang Cuilin , Chavarro Jorge E. , Rich-Edwards Janet W. , Wang Molin , Fawzi Wafaie W. , Manson JoAnn E. , Lee I-Min , Hu Frank B. , Tobias Deirdre K.
Published: December 2021

OBJECTIVE

We examined lifestyle factors with midlife weight change according to history of gestational diabetes mellitus (GDM) in a large longitudinal female cohort.

RESEARCH DESIGN AND METHODS

In the Nurses’ Health Study II, we categorized changes in lifestyle within 4-year periods and estimated their associations with concurrent changes in body weight (kilograms) among parous women after age 40 years by GDM history status (N = 54,062; 5.3% with a history of GDM) for the following: diet quality (Alternate Healthy Eating Index [AHEI]), leisure-time physical activity (PA), alcohol consumption, and smoking status.

RESULTS

Over a median follow-up of 13 years, average 4-year weight gain was 1.10 and 1.33 kg for women with and without prior GDM, respectively. Women with improved diet quality had favorable 4-year weight change, particularly those with a history of GDM (AHEI change [95% CI] from low to high −2.97 kg [−4.34, −1.60] vs. −1.19 kg [−1.41, −0.96] for GDM vs. non-GDM, respectively; P heterogeneity = 0.04). Increasing PA was associated with weight maintenance for GDM women only (PA increase [95% CI] from low to high 0.26 kg [−0.25, 0.77] vs. 0.90 kg [0.80, 1.01] for GDM vs. non-GDM, respectively; P heterogeneity = 0.02). For both GDM and non-GDM women, weight change did not differ significantly with change in alcohol consumption, while women who quit smoking had significant weight gain (4.38 kg for GDM and 3.85 kg for non-GDM).

CONCLUSIONS

Improvements in diet quality and PA were related to less weight gain in midlife among parous women, and the benefit of such improvements on weight management was particularly pronounced among women with a history of GDM.
Bio-inspired 3D micro structuring of a liver lobule via direct laser writing: A comparative study with SU-8 and SUEX
Authors: Zeußel Lisa , Hampl Jörg , Weise Frank , Singh Sukhdeep , Schober Andreas
Published: December 2021

Real biological tissues show a great variety of different geometric morphologies with special features on different geometric scales. An interesting example is the liver lobule that is the basic subunit of a liver. The lobule is a quasihexagonal macroscopic structure with periodic like so-called sinusoidal elements with structural features on the micro- and macroscale made of proteins, cells, and fluids. Various tools from micromachining and nanotechnology have demonstrated their capabilities to construct micromorphologies precisely, but even the reconstruction of such a system in technical polymers is challenging. In this work, the rapidly evolving technique of multiphoton polymerization has been explored for the construction of a scaffold that mimics the micromorphology of the liver with high resolution and detail up to the millimeter scale. At the end, a highly complex fluidically perfusable structure was achieved and simulations showed that the occurring shear stress, fluid velocity, and stream lines are comparable to the native liver lobule. Hereby, the photoresists SU-8 and SUEX TDFS were compared in terms of their processability, achievable resolution, and suitability for the intended application. Our results have shown that SUEX needs lower writing velocities but is easier to process and achieves a considerable higher resolution than SU-8. The scaffold could provide a base frame with a geometrically defined morphology for hepatic cells to adhere to, which could act as a starting point for cells to build new liver tissue for further integration in more complex systems.
Evaluation of the ASSIGN open-source deterministic address-matching algorithm for allocating Unique Property Reference Numbers to general practitioner-recorded patient addresses
Authors: Harper Gillian , Stables David , Simon Paul , Ahmed Zaheer , Smith Kelvin , Robson John , Dezateux Carol
Published: December 2021

IntroductionLinking places to people is a core element of the UK government's geospatial strategy. Matching patient addresses in electronic health records to their Unique Property Reference Numbers (UPRNs) enables spatial linkage for research, innovation and public benefit. Available algorithms are not transparent or evaluated for use with addresses recorded by health care providers.
ObjectivesTo describe and quality assure the open-source deterministic ASSIGN address-matching algorithm applied to general practitioner-recorded patient addresses.
MethodsBest practice standards were used to report the ASSIGN algorithm match rate, sensitivity and positive predictive value using gold-standard datasets from London and Wales. We applied the ASSIGN algorithm to the recorded addresses of a sample of 1,757,018 patients registered with all general practices in north east London. We examined bias in match results for the study population using multivariable analyses to estimate the likelihood of an address-matched UPRN by demographic, registration, and organisational variables.
ResultsWe found a 99.5% and 99.6% match rate with high sensitivity (0.999,0.998) and positive predictive value (0.996,0.998) for the Welsh and London gold standard datasets respectively, and a 98.6% match rate for the study population.
The 1.4% of the study population without a UPRN match were more likely to have changed registered address in the last 12 months (match rate: 95.4%), be from a Chinese ethnic background (95.5%), or registered with a general practice using the SystmOne clinical record system (94.4%). Conversely, people registered for more than 6.5 years with their general practitioner were more likely to have a match (99.4%) than those with shorter registration durations.
ConclusionsASSIGN is a highly accurate open-source address-matching algorithm with a high match rate and minimal biases when evaluated against a large sample of general practice-recorded patient addresses. ASSIGN has potential to be used in other address-based datasets including those with information relevant to the wider determinants of health.
Optimization of vibratory conveying upward by inclined track with polyharmonic normal vibrations
Authors:   Hetman Petro Sahaidachnyi National Army Academy, Vrublevskyi Іgor
Published: December 2021

The paper is devoted to the research of vibratory conveying of piece goods along an inclined track, performing harmonic longitudinal and polyharmonic normal vibrations. It is considered the conditions of reaching maximum conveying velocity at specified values of frequency and amplitude of longitudinal vibrations – the conditions of maximum dimensionless conveying velocity, depending on several dimensionless parameters in the moving modes without hopping. These dimensionless parameters are the inclination angle parameter – a ratio of an inclination angle tangent to a frictional coefficient, the intensive vibration coefficient – a ratio of the longitudinal amplitude of vibration to the amplitude of the first harmonic of normal vibration and frictional coefficient. Maximal conveying velocity is achieved at the certain values of normal vibration amplitudes and values of phase difference angles between longitudinal and normal vibrations, which are called optimal, and their values are dependent on these two dimensionless parameters, while maximum normal vibration acceleration should be equal to the gravitational acceleration. The research was made by approximate harmonic balance method and by numerical step-by-step integration method, which allows performing calculations with any given accuracy. The results obtained by the two methods are compared. To determine the maximal and optimal values of elevation angles, there are calculated the maximal value of the inclination angle parameter at which the value of dimensionless velocity is equal to zero, and the value of the inclination angle parameter at which a particle moves to a specified height in the minimum time. The optimal values of amplitudes of harmonics of polyharmonic normal vibration are determined in dependence on the inclination angle parameter with the number of harmonics from four to seven. The graphs of these dependencies are presented and the most important values of dimensionless parameters are presented in the table.
Influence of diamond component based on wurtzite boron nitride on wear resistance of cutting tool
Authors:   I.M. Frantsevich Institute for Problems of Materials Science of the National Academy of Sciences of Ukraine, Volkogon Volodymyr , Avramchuk Svitlana ,   I.M. Frantsevich Institute for Problems of Materials Science of the National Academy of Sciences of Ukraine, Fedoran Yuriy ,   I.M. Frantsevich Institute for Problems of Materials Science of the National Academy of Sciences of Ukraine, Kravchuk Andrii ,   I.M. Frantsevich Institute for Problems of Materials Science of the National Academy of Sciences of Ukraine, Pavlychuk Tetiana ,   I.M. Frantsevich Institute for Problems of Materials Science of the National Academy of Sciences of Ukraine, Antonyuk Viktor ,   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Avramchuk Kateryna ,   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”
Published: December 2021

The article is devoted to the study of the influence of the diamond component in a composite superhard material based on wurtzite boron nitride on the stability of the tool during turning of hardened steels in the mode of smooth turning and when processing intermittent surfaces. The aim of the work is to study the influence of the content of the diamond component in the composite superhard material based on wurtzite boron nitride on the stability of the tool. Based on the analysis of the main patterns of changes in the coefficient of friction depending on various factors, the evaluation of composites containing diamonds of different dispersion in comparison with other materials of this class. The results of the study of the technical level of composite polycrystalline superhard materials based on wurtzite boron nitride of different composition and determination of the efficiency of their use as a cutting tool in the machining of hardened steels are presented. The intensity of wear of composites in the cutting tool during processing of hardened steels is experimentally determined. It is established that the presence of a diamond component in the composite significantly affects the stability of the tool in the conditions of smooth turning due to heat dissipation in contact with the processed material. In the processing of hardened steels with the presence of shock loads, the phase state of the matrix component of the composite plays a decisive role. The obtained research results make it possible to determine the optimal composition and conditions for obtaining a composite material of the system “boron nitride – diamond”, which provides the most effective application of the cutting tool in practice.
Effectiveness of Information Service with Problem Based Learning Model to Improve Self Control of Students in Junior High School.
Authors: Jannah Raudhatul , Syukur Yarmis , Netrawati Netrawati
Published: December 2021

Students in learning activities show low self-control behaviors, namely during ongoing learning activities students often carry out activities that are not related to the learning process. Efforts can be made to improve students' self control by carrying out information services with problem based learning model . The research methodology used is quantitative, this type of research is Quasi Experiment with the design of The Non Equivalent Control Group Design. The subjects of this study were class VIII 3 students as an experimental group and class VIII 8 students as a control group at SMP Negeri 13 Padang. The research instrument used was a Likert model scale. Data were analyzed using the Wilcoxon Signed Ranks Test and the Kolmogorov-Smirnov Two Independent Sample test. The results showed that the information service with problem based learning model was effective to improve students' self control.
The Use of Counseling Cognitive Behavior Therapy (CBT) Approach to Change Students' Attitudes toward Cheating Behavior at SMK 1 Gunung Talang
Authors: Emdorizal Emdorizal , Karneli Yeni , Marlina Marlina
Published: December 2021

Students sometimes make cheating behaviors to achieve good grades in the exam. Cheating behavior is clearly cheating behavior that students should not do. The purpose of this study is to change the cheating behavior of students using the CBT approach, setting group. This study is a Quasi Experiment that uses quantitative methods and The Non-Equivalent Control Group Desig. The research subjects of class X of SMK Negeri 1 Gunung Talang was identified as having a tendency to cheat. The research instrument used a cheating behavior scale that fulfilled the requirements of the research instrument, then analyzed using the Wilcoxon Signed-Rank Test and the Kolmogorov Smirnov 2 Independent Samples test. The findings of this study show that in general CBT counseling group settings are effective for changing student attitudes toward cheating behavior. This finding can be discussed further.
Social Support for Adolescent Resilience in Dealing With Conflicts in Divorced Parents
Authors: Muhammad Muhadir , Nirwana Herman , Marjohan Marjohan
Published: December 2021

This research aims to determine social support for adolescent resilience in dealing with conflict in divorced parental environments that includes phase dimensions, and resilience strategies. This article is based on research using a qualitative method of case study type. Research subjects numbered 3 teenagers with the criteria of having divorced parents alive. Data collection techniques used in the form of in-depth interviews and observation. The data analysis technique used by researchers is guided by the Miles & Huberman model. The results of the analysis of research data indicate that the resilience phase that is passed by adolescents whose parents divorced live differently from each other. This is influenced by social support factors obtained by adolescents in facing life's challenges. The different phases through which each subject will also distinguish the resilience strategies used by each subject to survive in the face of conflict in the environment of divorced parents.
Description of Adolescent Understanding at SMK Negeri 9 Padang on the Dangers of Drug Abuse
Authors: Pertiwi Annisa , Karneli Yeni , Afdal Afdal
Published: December 2021

Drug abuse in adolescents is increasingly margined, drug abuse can cause a variety of negative impacts. Understanding is one of the most important aspects in the prevention of drug abuse. This research aims to determine the understanding of adolescents in SMK Negeri 9 Padang on the Dangers of Drug Abuse. This research uses quantitative descriptive methods. The population of this research was 435 students of class X of SMK Negeri 9 Padang. The research sample was 204 students. Based on research results 145 students (71%) Have an understanding of the dangers of drugs in the sufficient category, 55 students (27%) In good category, and 4 students (2%) In the less category. Understanding of students in SMK Negeri 9 Padang, the majority of which are in sufficient category and some students are in the category of less must be sought to be more improved.
Self-Adjustment and Social Conflict of Multicultural Students
Authors: Susanti Arlia Yulfi , Yusuf A Muri , Firman Firman
Published: December 2021

Social conflict became one of the phenomena commonly found in schools. To avoid conflict, good adjustment is needed. Meanwhile there are still many multi-ethnic students who have difficulty adjusting themselves to cause conflicts such as fights, disputes and debates that lead to violence. The aim is to find out the picture of adjustment and social conflict experienced by students and to know the relationship between adjustment and social conflict experienced by students. The research sample consisted of 104 students with Stratified Random Sampling. The instrument used was a questionnaire about adjusting the Likert Scale model with a reliability of 0.724 and a questionnaire about social conflict at 0.727. The results showed that there was a significant negative relationship between adjustment and social conflict experienced by students (r = -0.582). If the adjustment of students is getting better, the social conflicts experienced by students will decrease and vice versa. It means that some of the multi-ethnic students experience social conflict and counseling services are needed to resolve the conflict.
The Effectiveness of Group Counseling with Role-Playing Techniques to Increase Student Empathy
Authors: Nurhasanah Nurhasanah , S. Neviyarni , Effendi Z. Mawardi
Published: December 2021

Empathy is an important ability that must be developed and developed in students representing youth, as human beings who experience a transition of empathy need students to be able to improve what other people think and think that might happen quarrels, fights, bullying, and other actions, the lives of students more calm and peaceful. Today there has been an erosion of empathy in students this is caused by dependence on gadgets, instrumental learning, competition, differences, depression, alcohol, and other. The purpose of this study is to increase students' empathy using group guidance with role playing techniques. This research is a quasi-experimental study using quantitative methods and the non-equivalent control group design. The subject of this study were students of class VIII MT S N 1 Payakumbuh. The research instrument used an empathy scale that met the requirements of the research instrument, then analyzed using the Faired sample t test and the independent sample t test. This research cannot be applied to everyone, it needs further development. The findings of this study indicate group guidance with effective play techniques to improve students. These findings will be discussed further.
Relationship Adolescent perceptions about the maturity of the reproductive organs with sexual behavior deviations
Authors: Safitri Riana , Mudjiran Mudjiran , Effendi Z Mawardi
Published: December 2021

The deviations of sexual behavior are the behavior or behaviour that is not necessarily done by each individual in the course of teenagers as humans who are experiencing the transition or transitioning as not in accordance with the norms Applicable, whether it is religious norms, customs and legal norms. Nowadays, there have been many sexual behavior deviations done by the teenagers such as holding hands with the opposite sex, embracing, kissing, and even having intercourse like a husband and wife. Sexual behavior deviations are caused by internal and external factors. Internal factors can occur due to the sexual arousal that occurs in the age of adolescence and want to channel it to the opposite sex, while external factors can occur due to the environment that makes adolescents commit sexual behavior irregularities, as there are pornographic sites seen by teenagers, then they demonstrate with the opposite sex and lack the education. The purpose of this research is to look at the adolescent perception relationship about the maturity of reproductive tools with sexual behavior deviations. This study uses propotional stratiefied random sampling techniques. Based on research done, it was found that there was a significant link between juvenile perception of the maturity of reproductive tools and sexual behavior deviations.
The level of social adjustment of students to the school environment in preventing brawls
Authors: Sari Desi Puspita , Syahniar Syahniar , Karneli Yeni
Published: December 2021

One of the tasks of development in adolescents is social adjustment to the environment which is the school environment. Frequently, adolescents have problems in making social adjustments because this is one of the difficult tasks of adolescent development. If this condition is left, the teen will experience problems. Based on the existing phenomena, there are still students who have not been able to make social adjustments to the school environment so that such things can make students do deviant behavior like brawls. Fighting itself is a fight between groups. The population in this research was the student of SMK Negeri Padang which 140 students were chosen as the sample of the research. The sampling technique used was a purposive random sampling, and the data collection tools used the Social Adjustment Scale (SPS). The data were analyzed by using descriptive statistical methods with data processing using SPSS version 22. The results revealed that social adjustments in brawl prevention were classified as low (50.7%). Then, in the average, there was 38.6%, and in the high category, there was 10.7 %. Based on the results obtained, a follow-up can be carried out by making a guide to improve students' social adjustment to the school environment in preventing brawl.
Group Guidance to Increase Peer Counselor and Understanding of Bullying
Authors: Yuliana Yuliana , Neviyarni Neviyarni , Marlina Marlina
Published: December 2021

Peer counsellors have a low understanding of bullying and assume that bullying is common. The purpose of this research is to determine the effectiveness group counselling services to increase peer counsellor understanding of bullying. Methods Quasi Experiment study approach through the design of The Non-Equivalent Control Group. Data were collected using a peer counsellor understanding scale about bullying (53 valid items = 0.949). The study sample consisted of 10 peer counsellors as a control group and 10 peer counsellors as an experimental group who had a low and moderate understanding. Data were analyzed using the Wilcoxon Signed-Rank test and Kolmogorov-Smirnov two independent sample. The findings of this study showed that group counselling services are effective in improving the understanding of peer counsellor about bullying.
The Effectiveness of informational Services Through Small Group Discussion to Improve Students Tolerance Attitudes
Authors: Karisma Sally Putri , Neviyarni Neviyarni , Solfema Solfema
Published: December 2021

Tolerance is very important to maintain diversity in Indonesia, so it needs to be grown early. Students need to have tolerance to respect each other, accept and acknowledge the differences and diversity of religions, ethnicities, beliefs and opinions of others. This study aims to determine the effectiveness of information services with a small group discussion approach to improve student tolerance. The sample of this study consisted of 36 students selected by cluster random sampling techniques. The instrument used was a tolerance scale with a reliability of 0.844. Data analysis in this study used a one group pretest-posttest approach. The results showed that students have a very high attitude of tolerance, with an average achievement of 97.22%. The implications of this study are as a basis for counselors to improve student tolerance.