bluuebunny/crossref_metadata_2025 huggingface dataset:
Muzyka religijna w Rydze w czasach jej przynależności do Rzeczypospolitej. Znaczenie rękopisu tabulatury organowej S-Uu Vok. mus. i hs 88
Authors: Chankowska Zofia
Published: October 2023

W artykule został podjęty temat muzyki religijnej w kręgu katolickim w Rydze w latach 1582–1621. Był to czas działań rekatolizacyjnych podjętych przez przybyłych tam jezuitów, który charakteryzował się licznymi konfliktami na tle religijnym i świeckim między rdzennymi mieszkańcami tego miasta – luteranami a katolikami. Celem artykułu jest omówienie wzmianek w dokumentach świadczących o życiu muzycznym katolików w Rydze, a także przedstawienie jedynego zachowanego źródła muzycznego – tabulatury organowej skompilowanej w środowisku jezuickim, obecnie przechowywanej w Uppsala universitetsbibliotek pod sygnaturą Vok. mus. i hs. 88.
Silesia Sacra
Authors: Sukiennik Edgar
Published: October 2023

Recenzja książki ks. prof. Józefa Mandziuka pt. Silesia Sacra
Une tout autre forme d’authenticité. Travail du désir et anthropologie de la médiation chez Simone Weil
Authors: Simeoni Francesca
Published: October 2023

The aim of this article is to examine the actuality of Simone Weil's concept of the impersonal, as expressed in La personne et le sacré. To this end, I address the theme of authenticity by proposing two alternative models. According to the first model, "being oneself" corresponds to the immediate self-expression. Weil's critique of the "person's right to self-fulfillment", on the other hand, gives rise to an anthropology of mediation, which constitutes a second model centered on the notion of work. Hence, my original contribution consists in the argumentation of the thesis that in Weil's oeuvre the access to the self is structured in concordance to a "work of desire", which constitutes the human being's essence. Taking up the various allusions to the "desire for the good", scattered throughout the Weilian corpus, the article unveils what this affective work, that transforms the subject, consists of, and emphasizes the importance of the experience of the transcendent Good as a condition for a free interpretation of the value of the desired goods.
Experiência de acadêmicos de medicina em serviço de referência no tratamento de pé diabético no Amazonas
Authors: Maia André Lúcio Alves , Pereira André Luiz Pinto Mestrinho , Ferreira Vinícius Bacelar , Hora David Abraham Batista da , Guttemberg Filho Francisco Cruz , Guttemberg Victor do Valle , Patrício José Victor , Souto João Marcos Flores Cid , Martins Fabiana Mânica , Souza Celsa da Silva Moura
Published: October 2023

Objetivo: Relatar a experiência de estudantes de Medicina de uma universidade pública do Estado do Amazonas, obtida por meio de práticas desenvolvidas em Unidade Básica de Saúde (UBS) referência no tratamento de pé diabético. Relato de experiência: A atividade prática ocorreu por meio da participação ativa dos estudantes em todos os setores da UBS, auxiliando nos processos de encaminhamento, medicação e atendimento dos pacientes, a partir das instruções e métodos dos profissionais da instituição de saúde, que possibilitaram o entendimento na prática da atenção primária em saúde, interação com a população e com a equipe de saúde em busca, desenvolvimento de conhecimentos sobre responsabilidade social, criação de vínculos com a comunidade, trabalho em equipe e entendimento sobre o acompanhamento e tratamento do pé diabético. Considerações finais: A atividade possibilitou uma experiência única na carreira dos graduandos, aprimorando o conhecimento dos futuros profissionais da saúde sobre organização e funcionamento das UBS’s, atenção primária no estado do Amazonas e tratamento do Pé diabético.
DIAGNOSTIC PERFORMANCE OF DEEP LEARNING ARCHITECTURES IN THE DIAGNOSIS OF SJOGRENS SYNDROME- A SYSTEMATIC LITERTAURE REVIEW
Authors: Nagi Ravleen , Rakesh N. , Chachra Sanjay , Reddy Prashanthi , Vyas Tarun
Published: October 2023

Background:

Sjogren's Syndrome (SS) is a chronic, multifactorial autoimmune disease, characterized by clinical symptoms of dry mouth and dry eyes, due to chronic lymphocytic destruction of salivary and lacrimal glands, respectively. Proper diagnosis is a key towards better outcome. Recently introduced deep learning systems have ability to reflect the complexity of condition, with an aim to bring personalized medicine closer to the patients.

Aim:

The aim of this systematic review is to compile evidence-based studies pertaining to diagnostic performance of DL system and its algorithms in diagnosis of monitoring of SS.

Materials and method:

Computerized literature search was performed to select eligible articles from the following databases: PUBMED [MEDLINE], SCOPUS, SCIENCE DIRECT and COCHRANE DATABASE using specific keywords. The search was limited to articles published as full text in English, which were screened by two authors for eligibility.

Results:

Four studies satisfied our inclusion criteria, that suggested it to have high diagnostic accuracy when compared to inexperienced radiologist, but equivalent to those of experienced radiologists. Two studies found accuracy, sensitivity, and specificity of DL systems to be 89.5%, 90.0%, and 89.0%, for USG salivary gland images respectively whereas for CT images, the accuracy, sensitivity, and specificity was observed to be 96.0%,100% and 92.0%, respectively, and the diagnostic performance was higher from an inexperienced radiologist (p < 0.0001).

Conclusion:

DL systems have the potential to provide useful diagnostic support to inexperienced radiologists in assessment of images for the presence of characteristic features of SS. They could assist the radiologists in automated segmentation of salivary glands, and enables feature extraction in a reduced time with reduced risk of cognitive errors.
COVID 19 THIRD WAVE IN INDIA : A REVIEW
Authors: Arathi Menon P , Sahana S , Shiva Kumar GC , Hari R , Bagewadi Shivanad B
Published: October 2023

The nov-CoV-19 commonly known as COVID-19 reported first in Wuhan Province of China during late 2019 initiated as a common flu, escalated its spread across the Globe in no time. The WHO declared SARS-CoV- 2 as a pandemic and it affected every countries with high fatality and mortality rates. India witnessed a highly fatal first and second wave affecting millions of people. Wavering off the restrictions and attitude of the public determines the incidence and severity of a COVID-19 third wave in India. This paper reviews the prediction model analysis used to predict the third wave estimated using epidemiological data from the first and second wave of COVID-19. With complete preparedness and precautionary measures the impact could be limited. This review also analyses the potential barriers and overcoming them in tackling the third wave.
A NOVEL PERIODONTAL PLASTIC SURGICAL PROCEDURE FOR PAPILLA RECONSTRUCTION IN ANTERIOR AESTHETIC REGION WITH A VARIANT BEAGLE'S TECHNIQUE- A CASE REPORT
Authors: Singh Swati , Kumar Amit , Singh Nimmi , Singh Priyankar , Kumar Sanjay , Sharma A.K.
Published: October 2023

Black triangle, an open interproximal space between maxillary anterior teeth can create aesthetic concern among patients specially while smiling and during speech. There are several risk factors leading to the development of black triangle and the most common among them includes aging, periodontal disease, length of embrasure area, interproximal contact position, triangular- shaped crowns and root angulations. Various techniques like orthodontic correction, prosthetic veneers and various periodontal surgical methods have been used to cover these unesthetic open embrasures. Treating this black triangle can be best done by surgical techniques but it is challenging and very unpredictable. The purpose of this case report is to present a papilla regeneration technique with minimal surgical trauma in the reconstruction of papilla in the maxillary anterior region of a 36-year-old woman who presented with class II interdental papilla loss in 21 and 22 regions according to Nordland and Tarnow's classification. In the present study, a variant technique given by Beagle in 1992 was used to cover this open gingival embrasure. The technique uses a gingival flap from the labial aspect to close the open gingival embrasures thus improving the aesthetic as well as smile of the patient. The results obtained with this technique were satisfactory.
A NEW APPROACH FOR PLANNED UPPER INCISOR POSITION - AN OBSERVATIONAL PROSPECTIVE STUDY"
Authors: Anbarasu Prema , Kumar S. Saravana , Annamalai Indra
Published: October 2023

Background:

The profile of the patient is judged many a times by the position of the anterior teeth. Maxillary incisor labiolingual inclination and anteroposterior position play an essential role in the esthetics of the smiling profile. Hence the aim of the present study is to determine the planned incisor position in relation to the third palatal rugae an immutable landmark in the oral cavity

Materials and methods:

The study group consists of 80 participants consisting of 40 males and 40 females who satisfied the Andrew's six keys of occlusion. The impression of the upper dental arch was made using alginate impression material and the study casts were prepared with dental stone. The rugae pattern was marked on the study cast and the horizontal distance between the third palatal rugae to the incisal edge of upper incisor was measured using digital offset centerline Vernier caliper. The profile photograph of the participants was taken to verify skeletal class I relationship. The data collected were statistically analyzed using SPSS program.

Results:

The measured value between third rugae and incisal edge was 16-20 mm for females and 19-21mm for males. Therefore the planned incisor position for females is between 16-20 mm and 19-21mm for males.

Conclusion:

Knowing the ideal distance between the maxillary incisors and the third palatal rugae will help the orthodontist to plan the final anteroposterior position of the maxillary incisors during treatment.
POTENTIAL BIOLOGICAL AGENTS INVOLVED IN BIOTERRORISM - OBSERVATIONS FROM A DENTAL PERSPECTIVE
Authors: Viswanath Deepak , Singh Vikram , Pradhan Palini
Published: October 2023

Bioterrorism can be described as the intentional use of microbiological agents or their toxins as weapons in a wide sense. The intentional release or dissemination of a biological warfare agent (BWA), such as bacteria, viruses, rickettsiae, fungi, or biological toxins, is considered bioterrorism. Terrorists and military services are drawn to BWAs because of their unique qualities, which make them ideal for use as warfare agents. Several elements influence the success of a bioterrorism attack. Two major criteria are the type of BWA and the target population.
A SPECTRA OF FACIAL AND AURICULAR ANOMALY: BRACHIAL ARCH SYNDROME
Authors: Hada Pratiksha , Sharma Sakshi , Singh Vikram , Dubey Shivam
Published: October 2023

Hemifacial microsomia (HFM) is a congenital facial deformity involving the structures derived from first and second pharyngeal arches like temporomandibular joint, mandibular ramus and body, muscles of mastication, ear and sometimes facial nerve. HFM is the second most common developmental craniofacial anomaly after cleft lip and palate, which usually occurs unilaterally, but also may occur bilaterally. In the present article, we have reported a case of HFM in an 18 year old female with unilateral facial hypoplasia and deformed ear.
INFLAMMATORY/REACTIVE HYPERPLASIA'S: A REVIEW
Authors: Lahane Smita , Kulkarni Abhay , Birangane R.S. , Chaudhari Rohan , Rokade Rashmi R. , Karkade Aditee R.
Published: October 2023

The reactive lesions are comparatively common in the oral cavity that dentist face during routine examination because of the frequency with which the tissues are injured. They frequently result from a well-known provocation or injury such as plaque, calculus, or foreign bodies. Diagnosis and development of a treatment plan is difficult if dentists are not aware of the prevalence and clinical symptoms of these lesions. The aim of this article was to review the clinical features of various reactive hyperplastic lesions of the oral cavity. The most commonly found lesions are irritational fibroma, pyogenic granuloma, epulis fissuratum, peripheral giant cell granuloma.
IMPORTANCE OF HISTORY TAKING IN DENTISTRY.
Authors: Kaul Sidharth , Kedia Neal Bharat , Deb Aayush Ranjan , Gandikota Akshara , Koul Anjali , Kumari Sonali
Published: October 2023

Medical or dental professionals deal with humans who can communicate and discuss their problems; even people with special needs learn to communicate with sign languages. But alas in the fast paced life many of the professionals want to finish treating the person in their own ways, as they deem fit; rather than listening to what the patient is going through and what his/her expectations from the treatment are. Discussions take a back-seat; even though treatment following diagnosis and based on presenting complains should be the driving force. Communication with the adult patient or with the paedriatic patient and their guardians sets the environment where important information regarding the patients behaviour, their concerns and apprehensions can be ascertained culminating in wholesome treatment outcomes. Not only does this instil confidence in the patients and guardians but also makes treatment goals easily achievable for the professional.
Osteoid containing breast masses: A rad-path correlation
Authors: Palsetia Delnaz Rustom , Shet Tanuja , Haria Purvi , Thakur Meenakshi , Kulkarni Suyash Sureshchandra , Thakkar Palak Bhavesh , Katdare Aparna , Patil Asawari , Desai Sangeeta , Chauhan Sonal , Gala Kunal Bharat
Published: October 2023

Objectives:

Breast cancer is very common, of which the most common subtype is invasive ductal cancer (IDC). However, there are some rare types that also occur and manifest radiologically in a different manner.

Our article aims to emphasize a rare type of breast neoplasm, which shows osteoid matrix on pathology, and to correlate their imaging findings, thus enabling differentiation from usual carcinoma and aiding in further pathology typing.

Material and Methods:

A retrospective audit of breast masses with osteoid matrix was done from 2008 to 2021. The cases were retrieved from pathology archives. Twenty-five such cases were found with histopathology reports mentioning the osteoid matrix. Eight patients from these 25 had pre-operative mammograms as well as histopathology available for review. We evaluated these with mammograms with multiple parameters.

The project was approved by the Institutional Ethics Committee. Waiver of consent was obtained since there was no direct contact between the researcher and the participants.

Results:

Most cases of eccentric coarse calcification seen on mammography showed type IV matrix, in turn meaning that these cases had mature bone formation with tumor cell rimming type on histopathology.

Three tumors produced an osteoid matrix in our study, namely, Metaplastic carcinoma, primary osteosarcoma, and malignant phyllodes tumor.

Coarse calcification mostly indicates metaplastic carcinoma with osteosarcoma element. The preoperative diagnosis can guide pathology sampling.

Conclusion:

When eccentric, large, and coarse calcifications are visible within a mass on a mammogram, it raises suspicion of mature bone formation with tumor cell rimming within the tumor matrix.
Camouflaged cardiac alert: Correlation of breast arterial calcification with carotid intima media thickness for evaluation of cardiac risk
Authors: Ingole Sanjivanee Ujwal , Dev Bhawna , Varadarajan Suresh , Balakrishnan Sanchanaa Sree , Goyal Nishita , Chinnappan Sheela , Gnanavel Harini , Sai Venkata
Published: October 2023

Objectives:

To determine the association between breast arterial calcification (BAC) and carotid intima-media thickness (C-IMT) and, in turn, predict the risk of cardiovascular events. To independently access its relationship with other co-morbidities like diabetes mellitus (DM), hypertension (HTN), and menopause with BAC.

Material and Methods:

A total of 540 patients (270 with BAC and 270 without BAC) in the age group of 40–60 years who underwent mammograms at our institution between April 2021 to October 2021 were included in the study. In addition, an ultrasound was performed to evaluate the intima-media thickness in bilateral common carotid arteries 1 cm proximal to the carotid bulb. The mean C-IMT between the two groups (patients with and without BAC) was compared to understand the relationship between C-IMT and BAC. The independent relationship of BAC was also evaluated with the risk of co-morbidities like DM, HTN, and menopause.

Results:

The median C-IMT was higher in the group with BAC (0.85 mm, interquartile range (IQR) = 0.2) than in the group without BAC (0.6 mm, IQR = 0.10), which is statistically highly significant with p < 0.001. Further analysis among subgroups of age and DM also revealed IMT to be significantly higher in the group with BAC (0.85 mm, IQR = 0.20) compared to those without BAC (0.6 mm, IQR = 0.15) (p < 0.001). The median age in patients with BAC was significantly higher (57 years, IQR = 10 years) than those without BAC (48 years, IQR = 11.8 years) (p < 0.001). In the group with BAC, a higher proportion of patients were diabetics, hypertensives and had attained menopause, then in the subgroup without BAC.

Conclusion:

Patients with BAC had higher C-IMT, which in turn correlates with a higher risk of cardiovascular events. Hence, the presence of BAC can be used as a substitute marker for identifying patients with a higher risk of cardiovascular events and for ruling out co-morbidities such as DM and HTN.
Modern concepts of scleral buckling in the treatment of rhegmatogenous retinal detachment
Authors:   Eye Microsurgery Center, Yekaterinburg, Russian Federation, Kazaykin V.N. , Lizunov A.V. ,   Eye Microsurgery Center, Yekaterinburg, Russian Federation, Lipina M.A. ,   Eye Microsurgery Center, Yekaterinburg, Russian Federation
Published: October 2023

Relevance. Rhegmatogenous retinal detachment (RRD) is a serious problem of modern ophthalmology, leading to an irreversible decrease in vision and, in extreme cases, to its loss. The prevalence of RRD according to various sources varies from 8.9 to 24.4 cases per 100,000 population, in most cases these are patients of working age – 84–89%. Purpose. To analyze the role of extrascleral buckling in treatment of rhegmatogenous retinal detachment. Material and methods. In the search for materials, open electronic databases Google and Google Scholar, PubMed, Embase, MEDLINE and Web of Science were used, 58 sources were analyzed up to 2023. Results. At the beginning of the 20th century, retinal detachment irreversibly led to blindness, but starting from the late 1920s, the first surgical techniques appeared that made it possible to successfully restore its anatomical position. Extrascleral buckling (ESP) became an established treatment for retinal detachment with a long-term success rate of 93%. The vast majority of rebleeds ultimately continued to occur due to missed tears, inaccurate buckling, or inadequate retinopexy. Much has changed since the development in 1971 by R. Machemer of a device for vitrectomy through the pars plana, as a result of which the surgical focus shifted towards the vitreal cavity. Conclusion. Scleral buckling still remains an effective surgical intervention in a certain group of patients with retinal detachment, including combined operations, and its undoubted advantage is the unpretentiousness of technical support. Key words: rhegmatogenous retinal detachment, extrascleral buckling, encircling, cryopexy, encircling tape length
Assessment of changes in the retinal ellipsoid zone before and after surgical treatment of penetrating macular holes
Authors:   S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk Branch, Irkutsk, Russian Federation, Bronskii D.I. , Zaika V.A. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk Branch, Irkutsk, Russian Federation, Yakimov A.P. ,   S. Fyodorov Eye Microsurgery Federal State Institution, Irkutsk Branch, Irkutsk, Russian Federation
Published: October 2023

Relevance. Restoring the retinal integrity during surgical treatment of macular holes (MH) does not always guarantee a significant improvement in visual acuity in the postoperative period. The possibility of regeneration of the retinal ellipsoid zone (EZ), as well as the relationship between the structural restoration of the outer retina and the improvement of visual functions are very contradictory. Purpose. To assess the possibility and degree of repair of the ellipsoid zone in the early and long-term postoperative treatment of MH of medium and large diameters. Material and methods. A prospective study of 13 patients (13 eyes) – 12 women and 1 man with a MH of medium and large diameters was conducted. Patients were divided into 2 groups depending on the presence or absence of an EZ defect after 6 months postoperatively. The structure of the retina was evaluated according to OCT data and the visual acuity of patients in the distance before surgery, 1, 3 and 6 months after MR surgery. Results. In patients with complete restoration of retinal EZ, the initial size of the holes was 1.5 times smaller than in the comparison group, the time from the moment of diagnosis to surgery was 122.7±51.8 and 383.5±125.7 days, respectively. The defect of photoreceptors of the EZ by 1 month after surgery in patients of the first and second groups was 369.6±245.61 microns and 276.07±233.37 microns, respectively. By 6 months of follow–up in the first group, complete closure of the defect was observed, in the second group its decrease to 91.61±97.51 microns, while visual acuity in the first group was 0.46±0.83 by six months of followup and in 3 out of 5 cases it increased to 0.6–0.9, in the second group in all cases this indicator did not exceed 0.5. Conclusion. Complete regeneration of EZ was observed in 38.5% of cases 6 months after surgery, however, anatomical repair of the photoreceptor field of the macular area in the postoperative period does not guarantee improvement of visual functions in all patients. Key words: macular hole, ellipsoid zone, ellipsoid zone regeneration
Special form of strabismus – Brown's syndrome. Diagnostics and surgical treatment
Authors:   AVA-PETER, «Clinic Skandinavia», Saint-Petersburg, Russian Federation, Gorkin A.E.
Published: October 2023

Purpose. Clarification of indications for surgical treatment of Brown syndrome, choice of the optimal type of surgery and tactics of treatment of secondary overaction of the ipsilateral inferior oblique muscle (IO). Material and methods. Authors evaluate the effectiveness of various types of the superior oblique muscle (SO) weakening procedures based on the analysis of the results of surgical treatment of 65 patients (69 eyes) with Brown syndrome. In 53 cases, tenectomy was performed, and in 16 cases, recession/prolongation of SO. Results. Tenectomy of SO is more effective in surgical treatment of Brown syndrome. In 60 out of 65 (92%) operated patients it was possible to significantly improve the mobility of the operated eye upwards. Secondary overaction of the inferior oblique muscle was eliminated in next step of surgery. Conclusions. Surgical treatment of Brown's syndrome is staged. Indications for surgical treatment are: significant head abnormal position, hypotropia in the primary gaze and in adduction, binocular vision disturbance. The SO tenectomy has provided good functional results in treatment of patients with Brown's syndrome. Key words: Brown's syndrome, incomitant strabismus, superior oblique muscle, surgical treatment, tenectomy, recession, anterior transposition
Pengenalan Tulisan Tangan Karakter Aksara Batak Toba dengan Metode Convolutional Neural Network (CNN)
Authors: Turnip Alfael Maradu Andar , Fadillah Nurul , Munawir Munawir
Published: October 2023

Dari banyaknya budaya yang ada di Indonesia pasti memiliki bahasa yang berbeda beda. Dalam dialek suatu daerah ada yang memiliki huruf sendiri sebagai jenis komposisi atau penggambaran bahasa itu. Salah satu bahasa yang memiliki huruf tersendiri sebagai jenis penyusunannya adalah bahasa Batak Toba, yang juga disebut dengan aksara Batak Toba. Penelitian ini bertujuan untuk melatih komputer agar dapat mengenali karakter aksara Batak Toba. Dalam penelitian ini, digunakan metode Convolutional Neural Network (CNN) dalam mengenali tulisan tangan aksara Batak Toba. Hasil penelitian diperoleh  model CNN dengan ukuran kernel 3x3, hidden layer 1, ukuran citra masukan sebesar 150x150 pixel, menggunakan batas epoch sebesar 300 epoch dan dari model tersebut dihasilkan akurasi pada pengujian I sebesar 89.47 %, akurasi pada pengujian II sebesar 73.68 %, akurasi pada pengujian III sebesar 57,89%, akurasi pada pengujian IV sebesar 84,21% dan akurasi pada pengujian V sebesar 84,21%.
Sistem Rekomendasi Topik Skripsi Program Studi Informatika
Authors: Kurniawan Lukas , Filiana Agata , Virginia Gloria , Hartono Bastian Surya
Published: October 2023

Salah satu syarat kelulusan kuliah adalah lulus skripsi. Pada skripsi, mahasiswa perlu menentukan topik skripsi. Penentuan topik adalah hal yang penting pada skripsi, karena topik yang tepat akan mengurangi kendala dalam membuat skripsi [1]. Penulis melakukan analisa terhadap persentase nilai E pada nilai mata kuliah seminar dan skripsi. Hasil analisis menunjukan terdapat 21.6% dari 351 mahasiswa seminar yang mendapat nilai E dan 61.25% dari 240 mahasiswa yang belum dapat lulus skripsi. Hal tersebut menunjukan mahasiswa belum siap mengerjakan skripsi. FTI UKDW (Fakultas Teknologi Informasi Universitas Kristen Duta Wacana) ingin membuat sistem rekomendasi topik skripsi agar mahasiswa dapat memilih topik skripsi dengan tepat. Hasil penelitian, menunjukan sistem rekomendasi topik skripsi dapat dibuat menggunakan kombinasi K-Means++, cosine similarity, dan LDA Gibbs sampling. Sistem diimplementasikan pada framework Laravel.
Machine Learned Potentials by Active Learning from Organic Crystal Structure Prediction Landscapes
Authors: Butler Patrick W. V. , Hafizi Roohollah , Day Graeme
Published: October 2023

A primary challenge in organic molecular crystal structure prediction (CSP) is accurately ranking the energies of potential structures. While high-level solid-state density functional theory (DFT) methods allow for mostly reliable discrimination of the low energy structures, their high computational cost is problematic because of the need to evaluate tens to hundreds of thousands of trial crystal structures to fully explore typical crystal energy landscapes. Consequently, lower-cost but less accurate empirical force fields are often used, sometimes as the first stage of a hierarchical scheme involving multiple stages of increasingly accurate energy calculations. Machine learned potentials (MLPs), trained to reproduce the results of ab initio methods with computational cost close to that of force fields, can improve the efficiency of CSP by reducing or eliminating the need for costly DFT calculations at the final stages of CSP. Here, we investigate active learning methods for training MLPs with CSP datasets. The combination of active learning with the well-developed sampling methods from CSP yields potentials in a highly automated workflow that are relevant over a wide range of the crystal packing space. To demonstrate these potentials, we illustrate efficiently re-ranking large, diverse crystal structure landscapes to near-DFT accuracy from force field-based CSP, improving the reliability of the final energy ranking. Furthermore, we demonstrate how these potentials can be extended to more accurately model structures far from lattice energy minima through additional on-the-fly training within Monte Carlo simulations.
Antifungal and Antiparasitic Activity of Novel Metallocene-containing Fluconazole Derivatives
Authors: Lin Yan , Scalese Gonzalo , Bulman Christina , Vinck Robin , Blacque Olivier , Paulino Margot , Ballesteros-Casallas Andres , Pérez Díaz Leticia , Salinas Gustavo , Mitreva Makedonka , Weil Tobias , Cariou Kevin , Sakanari Judy , Gambino Dinorah , Gasser Gilles
Published: October 2023

The search for new anti-infectives based on metal complexes is gaining momentum. Among the different options taken by researchers, the one involving the use of organometallic complexes is probably the most successful one with a compound, namely ferroquine, already in clinical trial against malaria. In this study, we describe the preparation and in-depth characterization of 10 new (organometallic) derivatives of the approved antifungal drug fluconazole. Our rationale is that the sterol 14α-demethylase is an enzyme part of the ergosterol biosynthesis route in Trypanosoma and is similar to the one in pathogenic fungi. To demonstrate our postulate, docking experiments to assess the binding of our compounds with the enzyme were also performed. Our compounds were then tested on a range of fungal strains and parasitic organisms, including the protozoan parasite Trypanosoma cruzi (T. cruzi) responsible for Chagas disease, an endemic disease in Latin America and ranked as the third most prevalent parasitic disease after malaria and schistosomiasis. Of high interest, the most two potent compounds of the study on T. cruzi that contain a ferrocene or cobaltocenium were found to be harmless for an invertebrate animal model, namely Caenorhabditis elegans (C. elegans), without affecting motility, viability or development.
Laboratory Use Self-Efficacy of Turkish Pre-Service Science Teachers Trained in Different Teacher Education Programmes
Authors: Kızkapan Oktay , Tanık Önal Nagihan , Saylan Kırmızıgül Aslı
Published: October 2023

In Türkiye, the science teacher education programme changed in 2018. While physics, chemistry and biology courses were taught through theoretical and laboratory applications in the previous programme (Programme-I), the course hours of these courses were reduced and laboratory hours were abolished in the new programme (Programme-II). The present research, which adopts a causal-comparative design of quantitative research, aims to compare the laboratory self-efficacy of pre-service science teachers who attended these two science teacher education programmes. The research data was collected from 289 pre-service science teachers educated in Programme-I and II through the science laboratory use self-efficacy scale and then analysed using the independent samples t-test. The results show that the total scores of laboratory use self-efficacy of pre-service science teachers trained in Programme-I is significantly higher. The scores of the pre-service science teachers from Programme-I were also found to be significantly higher than those from Programme-II in terms of the sub-dimensions using the physical environment and equipment, working independently, and crisis management. On the other hand, there was no significant difference between the two programmes in the sub-dimension applying scientific process skills. These results and their implications are discussed in the light of current literature.
Using of ChatGPT in psychology research and practice
Authors: Melnyk Yu. B.
Published: October 2023

Background and Aim of Study:The use of artificial intelligence-based (AI-based) Chatbots in scientific research and everyday practice is becoming an integral part of most people’s lives. The field of psychology, like many others, has been influenced by artificial intelligence (AI). The aim of the study: to explore the possibilities of using AI-based Chatbots in psychological research and practice. Results: The role of OpenAI’s ChatGPT in the scientific research of academics and psychology practitioners was reviewed. The issues of using ChatGPT, which specializes in text, in theoretical research were discussed, as well as the potential applications of AI-based Chatbots in psychological practice. Conclusions: New AI technologies have transformed the scientific research ecosystem. Researchers, who actively use ChatGPT, should do so properly, taking into account the possibilities and limitations of using this toolkit in their research. Borrowing an AI-generated text for a research paper should be considered plagiarism. In addition to the risk to professional reputation, this can have a negative impact on the researcher’s own personal progress. People who do not have access to a qualified professional or who are financially constrained can use ChatGPT in psychological practice. In one way or another, these users must realize that the responsibility for the results and consequences of using such a toolkit rests entirely with them.
The Effect of Economic Development Level on the Spatial Diffusion Characteristics of Western Food Brands
Authors: Mi Hanwen
Published: October 2023

This study uses KFC as a representative brand of Western fast food to reflect the consumption ability of food, and Starbucks as a representative brand of the beverage industry to reflect the consumption ability of beverage, defines an S/K formula, compares the data with the level of regional economic development in order to present a certain correlation, and explores the spatial distribution characteristics of KFC and Starbucks, the influence of cultural institutions and economic influences on spatial selection. The study found that the ratio of the number of Starbucks stores to the number of KFC stores showed a positive relationship with the level of economic development (i.e., GDP and GDP per capita). The study not only empirically complements the current research on the spatial expansion of multinational retail firms but also provides validation for the theory of the spatial expansion of firms. At the same time, the study can provide some reference for site selection for other brands in similar fields entering the market.
Ilhan New's Independence Movement in the United States and the Korea Economy Society
Authors:   The Association for Korean Modern & Contemporary History, CHA Hyeonji
Published: October 2023

Compared to other representative indepedence movements, Ilhan New’s activity as a chairman of the Korea Economic Society has received less attention than it deserves.
In order to create positive public opinion about Korea in the U.S Ilhan New insisted on the necessity to utilize Korean military power during the Pacific War and on Korean’s capability of building and running their nation post-war. It played a positive role in encouraging the U.S. policy toward Korea to be more beneficial to Korea. However, Ilhan New judged that working through Planning and Research Board and the United Korean Committee in America Mission, to which he belonged, to be limited.
Therefore, he created the Korea Economic Society as a non-profit organization.
The Korea Economic Society’s main activity was to publish it’s own journal called Korea Economic Digest. It supplemented the limitations of Ilhan New’s previous press strategy that used only Korean activists and KED’s writers consisted of many American experts on Korea. These writers supported Ilhan New’s independence movement and attempted to persuade the U.S.
government-related ministries and public-private agencies by citing Korea’s strengths and potential values as seen by non-Koreans.
In other words, the Korea Economic Society could be considered a valuable association in that sense that defended and promoted Korea through journalism in response to the U.S. government’s tendency to draw negative conclusions through public researches on Korea during the Pacific War period. In addition, it was unique because it was a private association that reflected New Ilhan’s special independence movement strategy which was to promote Korea through the journalism.
Chung Woonsoo’s Life and Independence Movement before the Liberation of Korea from Japan
Authors:   The Association for Korean Modern & Contemporary History, HONG Jun-seok
Published: October 2023

The primary focus of this paper is to illuminate the life and contributions of Chung Woonsoo(鄭雲樹) to the Korean independence movement and explore its significance. The period that this study focuses on is from 1903, when he was born, to right after the liberation of Korea in 1945. Chung was educated predominantly at Protestant schools during the Japanese colonial era and further pursued theological studies in the United States.
His activism gained prominence during the Asia-Pacific War. Chung discerned the intricate link between the culmination of World War II and the restoration of Korean sovereignty. As a response, he fervently engaged in independence efforts in both America and China.
In Washington, D.C., Chung played various roles in the Korean Commission, aiding Syngman Rhee. He embarked on campaigns to secure support and empathy from Americans for the Korean independence cause and spearheaded initiatives to highlight Korea’s quest for autonomy within the American public sphere.
In 1944, Chung was commissioned as an officer in the U.S. Army. Subsequently, he was dispatched to China via Burma and assigned to the U.S.
14th Air Force in 1945. During this tenure, he took part in ‘The Eagle Project’, a collaborative endeavor between the Korean Independence Army(KIA) and the U.S. Office of Strategic Services(OSS). His responsibilities fostering KIA-OSS military collaborations, training communications for KIA’s Second Detachment members, and orchestrating advance operations into Korea.
Chung’s dedication to the independence movement was unwavering. Heemployed a gamut of strategies(from diplomacy and propaganda to direct armed resistance) in his relentless pursuit to end Japanese oppression and reinstate Korea’s sovereignty. Even though the anticipated advance operation into Korea did not materialize, Chung’s instrumental role in bolstering the collaboration between the KIA and OSS undeniably elevated the stature of both the Provisional Government of the Republic of Korea and the KIA.
- VACCINATION STATUS AND THE SEVERITY OF COVID-19 PATIENTS
Authors: Hartoyo Mugi , Budiyati Budiyati , Putra Riskiyana Sukandhi , Nizar Tajudin Hudaiby
Published: October 2023

Introduction: On January 30, 2020, the SARS-CoV-2 outbreak was a public health emergency of international concern. At the end of 2022 there was still the spread of COVID-19 even though the pandemic status had changed to endemic. One of the efforts to reduce the risk of being infected with COVID-19 is the provision of vaccines to the community. However, previous studies have shown that some people who have been vaccinated still have confirmed COVID-19 with varying severity and symptoms. The purpose of the study was to determine the relationship between vaccination status and the severity of COVID-19.

Method: This quantitative research with a retrospective cohort study was applied to 92 COVID-19 patients at a secondary hospital in Purbalingga, Central Java, Indonesia recruited by proportional simple random sampling technique. The data were collected from the medical records of COVID-19 patients from May to August 2021. The severity and symptoms of COVID-19 were determined based on the guidelines of the National Institutes of Health which include asymptomatic infection, mild symptoms, moderate symptoms, severe symptoms, and critical. The collected data were analyzed using the Fisher’s Exact test.

Results: Of the 92 respondents, there were 49 (53.35%) male patients and the most comorbid was diabetes mellitus with a total of 28 (30.4%) patients. Respondents who have not been vaccinated are 64 (69.6%) patients. Patients with a high severity level of COVID-19 were more frequently found among respondents who had not been vaccinated, 54 (58.7%). There is a relationship between vaccination status and the severity of COVID-19 (p = 0.000). The public is advised to complete the vaccine status that has been facilitated by the government.

Conclusion: Vaccination potentially reduces the severity of COVID-19.
THE EFFECTIVENESS OF HEALTH EDUCATION USING VIDEO MEDIA ON KNOWLEDGE OF PULMONARY TB PREVENTION IN NURSING STUDENT IN WAMENA
Authors: Ruben Sethiana Dewi , Purba Ellen Rosawita Veronica Purba Veronica , Gultom Elisabeth
Published: October 2023

Indonesia is the fifth country in Southeast Asia with the most cases of pulmonary TB. Papua is one of the provinces with a high incidence of pulmonary TB. One of the efforts to reduce the number of pulmonary TB is providing health education about tuberculosis prevention efforts using audiovisual media. This study aims to determine the effectiveness of health education using video media on knowledge of pulmonary TB prevention. The research used the design of The One Group Pre Test – Post Test, with the type of research being Quasi Experiment. It was carried out in the Wamena Nursing DIII Study Program with a sample of 32 respondents. Respondents were given a pre-test questionnaire and a health education intervention using video. After ten days of providing health education, respondents were given a questionnaire (post-test). Statistical analysis using Wilcoxon. The results showed a significant increase in knowledge about pulmonary TB prevention between the pre-test and post-test (p=0.000). It was concluded that health education using audiovisual media was more effective in providing information on the prevention of pulmonary TB.
THE EFFECTIVENESS OF GIVING SOY MILK TO INCREASING HAEMOGLOBIN (Hb) LEVELS IN ANEMIA ADOLSCENT IN THE WORK AREA OF THE CIHIDEUNG COMMUNITY HEALTH CENTER TASIKMALAYA CITY
Authors: Rahmani Syifa Haidar , Silalahi Uly Artha , Lestari Meti Widiya
Published: October 2023

The World Health Organization (WHO) states the prevalence of anemia in developing countries at 30-48%. Based on Riskesdas 2018, the prevalence of adolescent anemia in Indonesia is 32. The prevalence of anemia in the working area of ​​the Cihideung Health Center is 36.61%. This study aims to determine the effectiveness of soy milk administration against increased levels of haemoglobin (hb) in anemic adolescent girls. This study uses Quasy-Experiment design with Pretest and Posttest Control Group design. This research carried out in the working area of the Cihideung health center, Tasikmalaya City. The population in this study was adolescent girls aged 13-14 years who had anemia as many as 30 adolescents. The sampling technique to be used is total sampling. The data analysis used was univariate analysis and Wilcoxon bivariate analysis and Mann Withney difference test. The results of the study found that the average Hb level of the intervention group before treatment was 10.833, after treatment increased to 13.267, so there was an increase of 2.434. In the control group before treatment was 10,987, after treatment increased to 12,593, resulting in an increase of 1,606.  Wilcoxon statistical test was carried out, the intervention group obtained results (P = 0.001) and the control group (P = 0.001). Different test was carried out using Mann Withney's analysis, the results of the P Value value of 0.011. It can be concluded that there is a significant difference in average Hb levels between the intervention group and the control group
Physical Activity and Blood Glucose Levels in Diabetes Mellitus Patients
Authors: Amirudin Ikhwan
Published: October 2023

Diabetes mellitus is a metabolic disease characterized by hyperglycemia. One of the risk factors and management of patients with diabetes mellitus is physical activity which can control blood glucose levels. This study aimed to determine the relationship between physical activity and blood glucose levels. The study design used correlation analysis with a cross-sectional approach. The population in this study was all type 2 diabetes mellitus patients at Abdoel Moeloek General Hospital Lampung. The sample used in this study was 52 respondents with consecutive sampling techniques. The research instrument for measuring physical activity was the physical activity level (PAL), and blood glucose level was measured using a glucometer, and data was analyzed using the Spearman Rho Test. The results showed that 32 respondents (61.5%) had mild physical activity, and 41 respondents (78.8%) had high blood glucose levels. The results showed a significant relationship between physical activity with blood glucose levels (p value=0,000; α<0,05) in patients with diabetes mellitus at the Abdoel Moeloek General Hospital, Lampung. Physical activity can help the body to lower blood glucose by way of metabolism involving glucose stored in the muscles so that glucose in the blood will fill the glucose vacancies in the muscles. Higher the physical activity in patients with diabetes mellitus, the lower the glucose level.
THE EFFECTIVENESS OF EDUCATION AND INFORMATION ON THE ANXIETY LEVEL OF PRE-ELECTIVE SURGERY PATIENTS AT HVA HOSPITAL, PARE, KEDIRI
Authors: Dian Hadi Suprayetno Eko , Nuridayanti Anik , Priyanto Agus
Published: October 2023

Patients who undergo elective surgery are still anxious about the action that will be carried out when they enter the operating room, even though the surgeon has explained it as the Doctor Responsible for the Patient. The patient's anxiety in the operating room is characterized by frequent questions about the progress of the operation and a lack of cooperation when preparing a series of operations in the operating room. This research used a correlation research type, a Pre-Experimental research design with a population of elective pre-operative patients in the operating room at HVA Kediri Hospital. The total sample was 25 respondents using a sequential sampling technique. The data collection method used a questionnaire. Data were analyzed using the Wilcoxon test. The study results showed that before being given information and education to preoperative patients, almost half, 11 respondents (44%) experienced moderate anxiety. After being given information and education, it was found that the majority did not experience anxiety, 15 respondents (60%). There was a significant difference in anxiety between before and after being given education and information (p-value = 0.000; α <0.05). Education and information before the patient undergoes surgery can reduce the patient's anxiety level. Sufficient knowledge regarding the actions to be carried out means that the patient knows and does not ask questions about what will happen to him in the operating room.
A Torre de Babel da ciência econômica: é possível um tradutor universal?
Authors: Camarinha Lopes Tiago
Published: October 2023

Partindo da história bíblica da Torre de Babel para a origem dos diferentes idiomas, este artigo elabora a ideia de que a ciência econômica está fragmentada em distintas correntes ou escolas que não conseguem se comunicar adequadamente. Tradicionalmente esta dificuldade de interlocução é atribuída às diferentes metodologias de investigação e recomendação de políticas econômicas, refletindo principalmente divergências de caráter político e de contexto temporal e local. Este artigo defende que uma parte da incomunicabilidade entre as diferentes escolas de pensamento econômico não deriva desses fatores inerentes de desacordo, mas a fatores extrínsecos relacionados com a ausência de um tradutor universal entre os economistas. A dimensão, portanto, da linguagem precisa ser tratada com muita atenção para que os economistas não apenas se comuniquem melhor com o público, mas principalmente entre si. Realizando dois exercícios para pensar na viabilidade de um tradutor universal, argumento que é possível estabelecer um canal de diálogo inteligível entre membros de escolas diferentes, pelo menos em tópicos pontuais.