bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of patients with patent foramen ovale and cryptogenic stroke
Authors: Pristipino Christian , Anzola Gian Paolo , Ballerini Luigi , Bartorelli Antonio , Cecconi Moreno , Chessa Massimo , Donti Andrea , Gaspardone Achille , Neri Giuseppe , Onorato Eustaquio , Palareti Gualtiero , Rakar Serena , Rigatelli Gianluca , Santoro Gennaro , Toni Danilo , Ussia Gian Paolo , Violini Roberto ,   Italian Society of Invasive Cardiology (SICI-GISE),   Italian Stroke Association (ISA-AIS),   Italian Association of Hospital Neurologists, Neuroradiologists, Neurosurgeons (SNO),   Congenital Heart Disease Study Group of Italian Society Of Cardiology,   Italian Association Of Hospital Cardiologists (ANMCO),   Italian Society Of Pediatric Cardiology (SICP),   Italian Society of Cardiovascular Echography (SIEC),   Italian Society of Hemostasis and Thrombosis (SISET)
Published: June 2013

Objectives: To organize a common approach on the management of patent foramen ovale (PFO) and cryptogenic stroke that may be shared by different specialists. Background: The management of PFO related to cryptogenic stroke is controversial, despite an increase in interventional closure procedures. Methods: A consensus statement was developed by approaching Italian national cardiological, neurological, and hematological scientific societies. Task force members were identified by the president and/or the boards of each relevant scientific society or working group, as appropriate. Drafts were outlined by specific task force working groups. To obtain a widespread consensus, these drafts were merged and distributed to the scientific societies for local evaluation and revision by as many experts as possible. The ensuing final draft, merging all the revisions, was reviewed by the task force and finally approved by scientific societies. Results: Definitions of transient ischemic attack and both symptomatic and asymptomatic cryptogenic strokes were specified. A diagnostic workout was identified for patients with candidate event(s) and patient foramen ovale to define the probable pathogenesis of clinical events and to describe individual PFO characteristics. Further recommendations were provided regarding medical and interventional therapy considering individual risk factors of recurrence. Finally, follow‐up evaluation was appraised. Conclusions: Available data provided the basis for a shared approach to management of cryptogenic ischemic cerebral events and PFO among different Italian scientific societies. Wider international initiatives on the topic are awaited. © 2013 Wiley Periodicals, Inc.
Heterogeneous Silica‐Supported Ruthenium Phosphine Catalysts for Selective Formic Acid Decomposition
Authors: Gan Weijia , Dyson Paul J. , Laurenczy Gábor
Published: June 2013

The water‐soluble ruthenium(II)–mTPPTS complex (mTPPTS=meta‐trisulfonated triphenylphosphine) efficiently catalyzes the generation of hydrogen from formic acid in aqueous solution. This catalyst has been immobilized in a hydrophilic silica support to facilitate mobile portable applications. It was used in diluted formic acid solutions, in which the recycling of a liquid phase catalyst is problematic. A series of heterogenized catalysts have been prepared by the reaction of the ruthenium(II)–mTPPTS dimer and silica functionalized with diphenylphosphine groups via alkyl chains. The length of the alkylene chain separating the silica from the diphenylphosphine group has been varied in these catalysts—all of them catalyzing the decomposition of formic acid. The catalysts were easily separated from the solution and reused. The optimized catalytic system based on MCM41‐Si‐(CH2)2PPh2/Ru‐mTPPTS demonstrated an activity and stability comparable to those of the homogeneous catalyst: a turnover frequency of 2780 h−1 was obtained at 110 °C, and no ruthenium leaching was detected after turnover numbers of 71 000.
Preparation of Unconventional Dendrimers that Contain Rigid NHTriazine Linkages and Peripheral tert‐Butyl Moieties for CO2‐Selective Adsorption
Authors: Lee Cheng‐Hua , Tsai Meng‐Rong , Chang Yen‐Tzu , Lai Long‐Li , Lu Kuang‐Lieh , Cheng Kung‐Lung
Published: June 2013

Three unconventional dendrimers that contained rigid NHtriazine linkages and peripheral tert‐butyl moieties were prepared by using a convergent approach and characterized by 1H and 13C NMR spectroscopy, mass spectrometry, and elemental analysis. Based on a thermogravimetric analysis study, these dendrimers were observed to display thermal stability at about 300 °C. The NHtriazine moiety, which possessed protonated and proton‐free nitrogen sites (like the imidazole unit), displayed the capture of polarizable CO2 molecules through hydrogen‐bond and/or dipole–quadrupole interactions. In addition, the adsorption of various amounts of CO2 and N2 at different pressures suggests that the dendritic pores, which arise from the stacking of the middle co‐planar and rim protuberant dendrimers, Gn‐N∼N‐Gn (n=1–3), either swell or shrink at high pressure, thus indicating that these dendrimers may have a breathing ability.
Homogeneous Catalytic Hydrogenation of Amides to Amines
Authors: Coetzee Jacorien , Dodds Deborah L. , Klankermayer Jürgen , Brosinski Sandra , Leitner Walter , Slawin Alexandra M. Z. , Cole‐Hamilton David J.
Published: June 2013

Hydrogenation of amides in the presence of [Ru(acac)3] (acacH=2,4‐pentanedione), triphos [1,1,1‐tris‐ (diphenylphosphinomethyl)ethane] and methanesulfonic acid (MSA) produces secondary and tertiary amines with selectivities as high as 93 % provided that there is at least one aromatic ring on N. The system is also active for the synthesis of primary amines. In an attempt to probe the role of MSA and the mechanism of the reaction, a range of methanesulfonato complexes has been prepared from [Ru(acac)3], triphos and MSA, or from reactions of [RuX(OAc)(triphos)] (X=H or OAc) or [RuH2(CO)(triphos)] with MSA. Crystallographically characterised complexes include: [Ru(OAc‐κ1O)2(H2O)(triphos)], [Ru(OAc‐κ2O,O′)(CH3SO3‐κ1O)(triphos)], [Ru(CH3SO3‐κ1O)2(H2O)(triphos)] and [Ru2(μ‐CH3SO3)3(triphos)2][CH3SO3], whereas other complexes, such as [Ru(OAc‐κ1O)(OAc‐κ2O,O′)(triphos)], [Ru(CH3SO3‐κ1O)(CH3SO3‐κ2O,O′)(triphos)], H[Ru(CH3SO3‐κ1O)3(triphos)], [RuH(CH3SO3‐κ1O)(CO)(triphos)] and [RuH(CH3SO3‐κ2O,O′)(triphos)] have been characterised spectroscopically. The interactions between these various complexes and their relevance to the catalytic reactions are discussed.
Assembly of Cerium(III)‐Stabilized Polyoxotungstate Nanoclusters with SeO32−/TeO32− Templates: From Single Polyoxoanions to Inorganic Hollow Spheres in Dilute Solution
Authors: Chen Wei‐Chao , Li Hao‐Long , Wang Xin‐Long , Shao Kui‐Zhan , Su Zhong‐Min , Wang En‐Bo
Published: June 2013

A versatile one‐pot strategy was employed to synthesize three cerium(III)‐stabilized polyoxotungstates nanoclusters by combining cerium linkers and SeO32−/TeO32− heteroanion templates: K32Na16[{(XO3)W10O34}8{Ce8(H2O)20}(WO2)4‐ (W4O12)]⋅n H2O [X=Se, n=81 (1); X=Te, n=114 (2)] and K12Na22[{(SeO3)W10O34}8{Ce8(H2O)20}(WO2)4‐ {(W4O6)Ce4(H2O)14(SeO3)4(NO3)2}]⋅ 79 H2O (3), which are the first lanthanide‐containing polyoxotungstates with selenium or tellurium heteroatoms. The three clusters were characterized by single‐crystal X‐ray structure analysis, IR spectroscopy, thermogravimetric/differential thermal analysis, UV/Vis spectroscopy, ESI‐MS, and X‐ray photoelectron spectroscopy. Their electrochemical, photoluminescence, and magnetic properties were investigated. Their behavior in solution was studied by transmission electron microscopy, which showed that their single polyoxoanions assemble into intact, uniform‐sized, purely inorganic hollow spheres in dilute water/acetone solution.
Fluorescent Gold Nanoparticles: Synthesis of Composite Materials of Two‐Component Disulfide Gels and Gold Nanoparticles
Authors: Yamamoto Koji , An Zengjian , Saito Nozomi , Yamaguchi Masahiko
Published: June 2013

Pseudoenantiomeric ethynylhelicene oligomers containing a disulfide group formed two‐component gels, which showed different solvent properties from gels without the disulfide group. The disulfide gels reacted with gold nanoparticles, and the resulting organic–inorganic composite materials exhibited fluorescence emission between 600–800 nm, along with emission from the oligomers at 450 nm. The disulfide gels and isolated gold nanoparticles loaded with the oligomers did not show the former emission. The 600–800 nm emission reversibly disappeared upon sol formation with heating, which was accompanied by an enhancement of the emission at 450 nm. The novel emission was also observed in the solid state.
Energetic N‐Trinitroethyl‐Substituted Mono‐, Di‐, and Triaminotetrazoles
Authors: Zhang Qinghua , Zhang Jiaheng , Parrish Damon A. , Shreeve Jean'ne M.
Published: June 2013

A series of dense energetic N‐trinitroethyl‐substituted mono‐, bis‐, and tri‐5‐aminotetrazoles were obtained by reacting primary amines with in situ generated cyanogen azide, followed by the trinitroethyl functionalization that involves a condensation of a hydroxymethyl intermediate (prepared by a reaction with formaldehyde) with trinitromethane. These compounds were fully characterized by using multinuclear NMR spectroscopy, IR, elemental analysis, differential scanning calorimetry (DSC), and, in one case with 9, with single‐crystal XRD analysis. The heats of formation for all compounds were calculated with Gaussian 03 and then combined with experimental densities to determine the detonation pressures (P) and velocities (Dv) of the energetic materials. Interestingly, most of them exhibited high density, good thermal stability, acceptable oxygen balance, positive heat of formation, low impact sensitivity, and excellent detonation properties, which highlighted their practical application potentials as a fascinating class of highly energetic materials.
ChemInform Abstract: Crystal Structures of the Alkali Thiosulfates A2S2O3·nH2O (A/n = K/0, K/1/3, Rb/1).
Authors: Lehner Anna J. , Schindler Lisa V. , Roehr Caroline
Published: June 2013

The crystal structures of the title compounds are determined by single crystal XRD.
ChemInform Abstract: New Salt‐Inclusion Borate, Li3Ca9(BO3)7·2[LiF]: A Promising UV NLO Material with the Coplanar and High Density BO3 Triangles.
Authors: Yu Hongwei , Wu Hongping , Pan Shilie , Wang Ying , Yang Zhihua , Su Xin
Published: June 2013

Single crystals of the title compound are prepared by melting a mixture of Li2CO3, LiF, CaO, and H3BO3 in a molar ratio of 1.5:22:9:7 (Pt crucible, 850 °C, 20 h).
ChemInform Abstract: Preparation, Structure, and Electrochemistry of Layered Polyanionic Hydroxysulfates: LiMSO4OH (M: Fe, Co, Mn) Electrodes for Li‐Ion Batteries.
Authors: Subban Chinmayee V. , Ati Mohamed , Rousse Gwenaelle , Abakumov Artem M. , Van Tendeloo Gustaaf , Janot Raphael , Tarascon Jean‐Marie
Published: June 2013

The title compounds are prepared by ball milling of mixtures of LiOH and anhydrous MSO4 (M: Fe, Co, Mn) precursors.
ChemInform Abstract: New Alkali‐Metal Gallium Selenites, AGa(SeO3)2 (A: Li, Na, K, and Cs): Effect of Cation Size on the Framework Structures and Macroscopic Centricities.
Authors: Lee Dong Woo , Ok Kang Min
Published: June 2013

The structures of (IVa) (tetragonal, space group I$\bar 4$2d, Z = 8), (IVb,c) (orthorhombic, Pnma, Z = 4) and (IVb) (monoclinic, C2/m, Z = 8) are determined by single‐crystal XRD.
ChemInform Abstract: High Structural Complexity of Potassium Uranyl Borates Derived from High‐Temperature/High‐Pressure Reactions.
Authors: Albrecht‐Schmitt Thomas E. , et al. et al.
Published: June 2013

K12 [(UO2)19(UO4) (B2O5)2(BO3)6 (BO2OH)O10]·nH2O (I), K4 [(UO2)5(BO3)2O4] ·H2O (II), and K15 [(UO2)18(BO3)7O15] (III) are synthesized by high‐pressure solid state reaction of KNO3, H3BO3, SiO2, Al2O3, and UO2(NO3)2·6H2O in molar ratios of K:B:Si:Al:U = 2:6:5:5:1 and KOH solution for (I) and K:B:Si:U = 2:6:5:1 without Al2O3 and KOH addition for compounds (II) and (III) (Au capsule, 650 °C, 200 MPa, 7 d).
ChemInform Abstract: A Microbial‐Mineralization Approach for Syntheses of Iron Oxides with a High Specific Surface Area.
Authors: Yagita Naoki , Oaki Yuya , Imai Hiroaki
Published: June 2013

γ‐Fe2O3 and α‐Fe2O3 with BET surface areas of 253 and 148 m2/g, resp., are synthesized by thermal treatment of γ‐FeOOH or α‐FeOOH precursors at 400 °C for 2—3 min.
ChemInform Abstract: Iodine‐Templated Assembly of Unprecedented 3d—4f Metal—Organic Frameworks as Photocatalysts for Hydrogen Generation.
Authors: Hu Xiao‐Li , Sun Chun‐Yi , Qin Chao , Wang Xin‐Long , Wang Hai‐Ning , Zhou En‐Long , Li Wen‐E , Su Zhong‐Min
Published: June 2013

The isotypic compounds (III) crystallize in the monoclinic space group P21/c with Z = 2 (single crystal XRD) and exhibit three‐dimensional frameworks with triangular helical channels, which accomodate linear polyiodide chains.
ChemInform Abstract: Efficient Palladium‐Catalyzed C—O Hydrogenolysis of Benzylic Alcohols and Aromatic Ketones with Polymethylhydrosiloxane.
Authors: Wang Hu , Li Li , Bai Xing‐Feng , Shang Jun‐Yan , Yang Ke‐Fang , Xu Li‐Wen
Published: June 2013

A simple and new method for the title reaction is developed.
ChemInform Abstract: Tandem Reactions Involving 1‐Silyl‐3‐boryl‐2‐alkenes. New Access to (Z)‐1‐Fluoro‐1‐alkenes, Allyl Fluorides, and Diversely α‐Substituted Allylboronates.
Authors: Mace Aurelie , Tripoteau Fabien , Zhao Qian , Gayon Eric , Vrancken Emmanuel , Campagne Jean‐Marc , Carboni Bertrand
Published: June 2013

The reactions occur with high (Z)‐selectivity regardless of the starting material′s configuration.
ChemInform Abstract: Direct Reductive Amination of Aldehyde Bisulfite Adducts Induced by 2‐Picoline Borane: Application to the Synthesis of a DPP‐IV Inhibitor.
Authors: Faul Margaret , Larsen Rob , Levinson Adam , Tedrow Jason , Vounatsos Filisaty
Published: June 2013

The title reaction allows an efficient access to a wide range of secondary amines including the DPP‐IV inhibitor (VIII).
ChemInform Abstract: N‐Arylation of Heterocycles Catalyzed by Activated Copper in Pure Water.
Authors: Yang Qichao , Wang Yufang , Lin Dong , Zhang Mingjie
Published: June 2013

A simple and environmentally friendly protocol is developed which works in the absence of any ligand.
ChemInform Abstract: Silver‐Catalyzed Hydrotrifluoromethylation of Unactivated Alkenes with CF3SiMe3.
Authors: Wu Xinyue , Chu Lingling , Qing Feng‐Ling
Published: June 2013

For the first time the title reaction is presented providing a wide range of trifluoromethylated alkanes.
ChemInform Abstract: Sulfonated Polypyrene (S‐PPR) as Efficient Catalyst for Esterification of Carboxylic Acids with Equimolar Amounts of Alcohols Without Removing Water.
Authors: Tanemura Kiyoshi , Suzuki Tsuneo
Published: June 2013

The reusable catalyst efficiently promotes the esterification of carboxylic acids as well as transesterifications.
ChemInform Abstract: Zn(OTf)2‐Promoted Chemoselective Esterification of Hydroxyl Group Bearing Carboxylic Acids.
Authors: Mamidi Narsimha , Manna Debasis
Published: June 2013

This is mild and highly chemoselective method for the esterification and amidation of aromatic and aliphatic carboxylic acids.
ChemInform Abstract: Efficient Synthesis of Silylated 2,2‐Difluorostyrene Derivatives Through Suzuki—Miyaura Cross‐Coupling of 2,2‐Difluoro‐1‐iodo‐1‐silylethenes.
Authors: Turcotte‐Savard Marc‐Olivier , Paquin Jean‐Francois
Published: June 2013

The presented method offers some advantages over the previous one including enhanced scope, higher yields, ease of purification and significant reduction of desilylated side‐products.
ChemInform Abstract: The Regio‐ and Stereospecific Intermolecular Dehydrative Alkoxylation of Allylic Alcohols Catalyzed by a Gold(I) N‐Heterocyclic Carbene Complex.
Authors: Mukherjee Paramita , Widenhoefer Ross A.
Published: June 2013

This publication contains studies concerning regioselectivity and chirality transfer.
ChemInform Abstract: Synthesis and Biological Evaluation of Some Substituted‐2‐N‐(5‐chloro‐2‐methoxy‐4‐methylphenylsulfonyl) Glutamic Acid Derivatives Against Prostate Cancer Cell Line PC3.
Authors: Hassan Ghaneya Sayed , Abdel Rahman Doaa Ezzat
Published: June 2013

Compounds (IVa‐d), (V), and (VI) display potent activity against PC3 tumor cell line.
ChemInform Abstract: Stereoselective Rh2(S‐IBAZ)4‐Catalyzed Cyclopropanation of Alkenes, Alkynes, and Allenes: Asymmetric Synthesis of Diacceptor Cyclopropylphosphonates and Alkylidenecyclopropanes.
Authors: Lindsay Vincent N. G. , Fiset Dominic , Gritsch Philipp J. , Azzi Soula , Charette Andre B.
Published: June 2013

This is the first catalytic asymmetric cyclopropanation of allenes with diacceptor diazo compounds.
ChemInform Abstract: Generation of Molecular Complexity from Cyclooctatetraene: Preparation of Optically Active Protected Aminocycloheptitols (XI) and Bicyclo[4.4.1]undecatriene (VI).
Authors: El‐Mansy Mohamed F. , Sar Anobick , Lindeman Sergey , Donaldson William A.
Published: June 2013

The (6‐styryl‐cycloheptadienyl)iron cation (III) reacts with various nucleophiles to give products which can be further transformed into the title compounds.
ChemInform Abstract: The Pauson—Khand Reaction of Medium Sized trans‐Cycloalkenes.
Authors: Lledo Agusti , Fuster Aida , Reves Marc , Verdaguer Xavier , Riera Antoni
Published: June 2013

Starting carbonyl dicobalt complexes are readily prepared from Co2(CO)8 and the respective alkynes.
ChemInform Abstract: Aminocatalytic Asymmetric exo‐Diels—Alder Reaction with Methiodide Salts of Mannich Bases and 2,4‐Dienals to Construct Chiral Spirocycles.
Authors: Zhang Shan‐Jun , Zhang Jun , Zhou Qing‐Qing , Dong Lin , Chen Ying‐Chun
Published: June 2013

Labile α‐methylene carbonyl compounds are generated in situ from bench‐stable methiodide Mannich salts.
ChemInform Abstract: Synthesis of Adamantane‐Based Trimeric Cationic Surfactants.
Authors: Zhu Hua , Guo Jianwei , Yang Chufen , Liu Sa , Chui Yingde , Zhong Xing
Published: June 2013

Three trimeric quaternary ammonium surfactants having different carbon chains (I) are synthesized.
ChemInform Abstract: Simplifying Nickel(0) Catalysis: An Air‐Stable Nickel Precatalyst for the Internally Selective Benzylation of Terminal Alkenes.
Authors: Standley Eric A. , Jamison Timothy F.
Published: June 2013

The products contain small amounts of the respective linear alkene as by‐product.
ChemInform Abstract: Reactions of Difluorocarbene with Organozinc Reagents.
Authors: Levin Vitalij V. , Zemtsov Artem A. , Struchkova Marina I. , Dilman Alexander D.
Published: June 2013

The generated α‐difluorinated organozinc reagents are reported to be reasonably stable in solution.
ChemInform Abstract: Aromatic Fluoro‐de‐triazenation with Boron Trifluoride Diethyl Etherate under Non‐protic Acid Conditions.
Authors: Kovac Mitja , Anderluh Marko , Vercouillie Johnny , Guilloteau Denis , Emond Patrick , Mavel Sylvie
Published: June 2013

A rapid and synthetically useful fluorination of 1‐aryltriazene derivatives (III) under controlled microwave heating furnishing corresponding aryl fluorides (IV) is developed.
ChemInform Abstract: Catalytic Reduction of ortho‐ and para‐Azidonitrobenzenes via tert‐Butoxide Ion Mediated Electron Transfer.
Authors: Burnley James , Carbone Giorgio , Moses John E.
Published: June 2013

The novel method employing tert‐butoxide as the reductant and a thiazolium salt as the catalyst allows the chemoselective reduction of an azide in the presence of a sensitive nitro group.
ChemInform Abstract: Palladium‐Catalyzed Regioselective Halogenation of Aromatic Azo Compounds.
Authors: Ma Xian‐Tao , Tian Shi‐Kai
Published: June 2013

A wide range of different substituted diaryl‐azo compounds can be brominated or iodinated with excellent ortho‐selectivity under mild reaction conditions.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Acylation of N‐Benzyltriflamides with Aldehydes via C—H Bond Activation.
Authors: Sharma Satyasheel , Park Jihye , Park Eonjeong , Kim Aejin , Kim Minyoung , Kwak Jong Hwan , Jung Young Hoon , Kim In Su
Published: June 2013

An efficient protocol for the title reaction is developed.
ChemInform Abstract: Facile and Controllable Synthesis of Multiply Substituted Benzenes via a Formal [3 + 3] Cycloaddition Approach.
Authors: Shu Zhen‐Cao , Zhu Jian‐Bo , Liao Saihu , Sun Xiu‐Li , Tang Yong
Published: June 2013

An efficient protocol for preparation of di‐ to pentasubstituted benzene derivatives from α,β‐unsaturated carbonyl derivatives and ylides is presented.
ChemInform Abstract: Electrophilic Trifluoromethylthiolation of Allylsilanes with Trifluoromethanesulfanamide.
Authors: Liu Jianbo , Chu Lingling , Qing Feng‐Ling
Published: June 2013

The new CH3COCl‐promoted allylic trifluoromethylthiolation allows the efficient synthesis of a wide range of allylic trifluoromethylthiolated compounds under mild conditions.
ChemInform Abstract: Organocatalytic Asymmetric Addition of Thiols to Trifluoromethylaldimine: An Efficient Approach to Chiral Trifluoromethylated N,S‐Acetals.
Authors: Fang Xin , Li Qing‐Hua , Tao Hai‐Yan , Wang Chun‐Jiang
Published: June 2013

This novel reaction affords the biologically important products (III) and (V) in excellent yields and with high enantioselectivities.
ChemInform Abstract: Tetrabutylammonium Iodide Catalyzed Allylic Sulfonylation of Baylis—Hillman Acetates with Sulfonylhydrazides in Water.
Authors: Li Xiaoqing , Xu Xiangsheng , Tang Yucai
Published: June 2013

A new protocol for the synthesis of a wide range of different substituted allyl aryl sulfone derivatives is developed (14 examples).
ChemInform Abstract: Microwave‐Assisted Synthesis of Alkyl Thiocyanates.
Authors: Bound D. James , Bettadaiah B. K. , Srinivas P.
Published: June 2013

A high selective and more efficient protocol for the synthesis of the title compounds to hitherto known procedures is presented.
ChemInform Abstract: Ligand‐Controlled Iron‐Catalyzed Cross Coupling of Benzylic Chlorides with Aryl Grignard Reagents.
Authors: Kawamura Shintaro , Nakamura Masaharu
Published: June 2013

The selective cross‐coupling of benzylic chlorides (II) with aryl Grignard reagents (I) is achieved in the presence of catalytic amounts of FeCl2 and electronically tuned ortho‐phenylenebisphosphine ligands.
ChemInform Abstract: Copper‐Catalyzed Oxidative Coupling of Alkenes with Aldehydes: Direct Access to α,β‐Unsaturated Ketones.
Authors: Wang Jing , Liu Chao , Yuan Jiwen , Lei Aiwen
Published: June 2013

A novel approach for the synthesis of α,β‐ unsaturated ketones is developed tolerating a variety of functional groups on both aldehyde and alkene.
ChemInform Abstract: Stereodefined Cyclopentanes by Hydroarylation—Ring Opening.
Authors: Polivkova Jana , Piotrowski David W.
Published: June 2013

Title compounds are synthesized by ring opening of protected lactams [(IV) and (V), resp.], which are derived from hydroarylation of (I), using a variety of nucleophiles.
ChemInform Abstract: Iron‐Catalyzed Benzannulation Reactions of 2‐Alkylbenzaldehydes and Alkynes Leading to Naphthalene Derivatives.
Authors: Zhu Shifa , Xiao Yelin , Guo Zhengjiang , Jiang Huanfeng
Published: June 2013

This new and efficient method is applicable to various substituted benzaldehydes and alkynes including diynes and triynes.
ChemInform Abstract: pH‐Sensitive DNA Cleaving Agents: In situ Activation by Ring Contraction of Benzo‐Fused Cyclobutanols.
Authors: Nagamoto Yuuki , Hattori Akira , Kakeya Hideaki , Takemoto Yoshiji , Takasu Kiyosei
Published: June 2013

Benzo‐fused cyclobutanols such as (I) and (III) are developed as novel DNA cleavage compounds.
ChemInform Abstract: Synthesis and Evaluation of 3‐[(2,4‐Dioxo‐1,3,8‐triazaspiro[4.6]undec‐3‐yl)methyl]benzonitrile Derivatives as Potential Anticonvulsants.
Authors: Madaiah Malavalli , Prashanth Maralekere K. , Revanasiddappa Hosakere D. , Veeresh Bantal
Published: June 2013

30 Title compounds of type (IX) or (XI) are prepared and tested for their pharmacological activities.
ChemInform Abstract: Convenient Synthesis of Adamantyl‐Substituted β‐Lactams via Uncatalyzed Staudinger Reaction.
Authors: Liu Mingshun , Chen Yaqing , Fu Nanyan
Published: June 2013

Title compounds (III) are synthesized via in situ generated adamantylketene.
ChemInform Abstract: 5‐Substituted‐2‐furaldehydes: A Synthetic Protocol Utilizing an Organozinc Route.
Authors: Kim Seung‐Hoi , Rieke Reuben D.
Published: June 2013

A facile and mild synthetic route for the preparation of a wide range of the title compounds is developed.
ChemInform Abstract: Intramolecular C(sp3)—N Coupling by Oxidation of Benzylic C,N‐Dianions.
Authors: Jeffrey Jenna L. , Bartlett Emily S. , Sarpong Richmond
Published: June 2013

The presented coupling cannot be effected using any other established methods.
ChemInform Abstract: Sequential [6 + 2], [2 + 2], and [3 + 2] Annulations for Rapid Assembly of Multiple Fragments.
Authors: Mahendar Velisoju , Oikawa Hideaki , Oguri Hiroki
Published: June 2013

Assembly of four components through sequential [6 + 2], [2 + 2], and [3 + 2] annulations on azulenone (I) allows access to a natural product‐inspired densely functionalized hexacyclic scaffold (X) with exquisite control of ten consecutive stereocenters.
ChemInform Abstract: A General, Enantioselective Synthesis of 1‐Azabicyclo[m.n.0]alkane Ring Systems.
Authors: Senter Timothy J. , Schulte Michael L. , Konkol Leah C. , Wadzinski Tyler E. , Lindsley Craig W.
Published: June 2013

The novel approach to the title compounds, subunits of various natural product classes, involves the highly diastereoselective allylation of sulfimine (II).
ChemInform Abstract: Regioselective Synthesis of Isoxazole—Mercaptobenzimidazole Hybrids and Their in vivo Analgesic and Antiinflammatory Activity Studies.
Authors: Vadde Ravinder , et al. et al.
Published: June 2013

A facile route for the synthesis of the title compounds (III) utilizing a NHC‐catalyzed 1,2‐dipolar cycloaddition of alkynes and nitrile oxides is described.
ChemInform Abstract: Synthesis of Pyridines by Carbenoid‐Mediated Ring Opening of 2H‐Azirines.
Authors: Loy Nicole S. Y. , Singh Alok , Xu Xianxiu , Park Cheol‐Min
Published: June 2013

A novel strategy of activation of 2H‐aziridines provides a broad range of highly conjugated poly‐arylpyridine systems by formal [3 + 3]‐cycloaddition.
ChemInform Abstract: Synthesis of Quinolones by Nickel‐Catalyzed Cycloaddition via Elimination of Nitrile.
Authors: Nakai Kenichiro , Kurahashi Takuya , Matsubara Seijiro
Published: June 2013

Substituted quinolones are efficiently synthesized by this new nickel‐catalyzed cycloaddition of o‐cyanophenylbenzamide derivatives with alkynes.
ChemInform Abstract: Discovering Some Novel 7‐Chloroquinolines Carrying a Biologically Active Benzenesulfonamide Moiety as a New Class of Anticancer Agents.
Authors: Al‐Dosari Mohammad Salem , Ghorab Mostafa Mohamed , Al‐Said Mansour Sulaiman , Nissan Yassin Mohammed
Published: June 2013

Out of 24 examples tested, compound (VI) shows highest anticancer activity in vitro.
ChemInform Abstract: Development of a New Cascade Reaction for Convergent Synthesis of Pyrazolo[1,5‐a]quinoline Derivatives under Transition‐Metal‐Free Conditions.
Authors: Kato Jun‐ya , Aoyama Hiroshi , Yokomatsu Tsutomu
Published: June 2013

The title reaction involves an aromatic nucleophilic substitution of 1H‐pyrazoles (II) and (IV) with 2‐fluorobenzaldehyde derivatives (I), followed by a Knoevenagel cyclization of the resulting adducts.
ChemInform Abstract: Spiro Heterocycles as Potential Inhibitors of SIRT1: Pd/C‐Mediated Synthesis of Novel N‐Indolylmethyl Spiroindoline‐3,2′‐quinazolines.
Authors: Rambabu D. , Raja Guttikonda , Sreenivas B. Yogi , Seerapu G. P. K. , Kumar K. Lalith , Deora Girdhar Singh , Haldar Devyani , Rao M. V. Basaveswara , Pal Manojit
Published: June 2013

A series of novel spiro‐indolinequinazoline derivatives (III) (14 examples) are designed and synthesized via a Pd‐C/Cu‐mediated tandem coupling‐cyclization strategy.
ChemInform Abstract: 6‐Polyfluoroalkylated 2‐Thiouracils in the Synthesis of Pyrimido [2,1‐b][1,3,5]thiadiazines (IV) by the Double Mannich Reaction.
Authors: Khudina Ol'ga G. , Ivanova Anna E. , Burgart Yanina V. , Saloutin Victor I. , Kravchenko Marionella A.
Published: June 2013

Some of the obtained pyrimidothiadiazines (IV) posses weak tuberculostatic activity.
ChemInform Abstract: Enantioselective β‐Boration of Acyclic Enones by a [2.2]Paracyclophane‐Based N‐Heterocyclic Carbene Copper(I) Catalyst.
Authors: Zhao Lei , Ma Yudao , He Fuyan , Duan Wenzeng , Chen Jianqiang , Song Chun
Published: June 2013

The new planar and centrally chiral triazolium salt (NHC) efficiently promotes the asymmetric conjugate boration of acyclic enones yielding synthetically important organo‐boron compounds with excellent enantioselectivity in short times.
ChemInform Abstract: Reduction of the Dihalocyclopentasilanes. A Quest for a Homocyclic Silylene.
Authors: Xiao Xu‐Qiong , Zhao Hui , Xu Zheng , Lai Guoqiao , He Xiao‐Lin , Li Zifang
Published: June 2013

Reduction of dibromocyclopentasilane (I) with potassium graphite affords a fused tricyclic silane (II) via a homocyclic silylene intermediate.
ChemInform Abstract: Diametric Stereocontrol in Dynamic Catalytic Reduction of Racemic Acyl Phosphonates: Divergence from α‐Keto Ester Congeners.
Authors: Corbett Michael T. , Johnson Jeffrey S.
Published: June 2013

An unexpected reversal in facial selectivity is observed in the Ru(II)‐catalyzed asymmetric transfer hydrogenation of acyl phosphonates in comparison to their previously studied structural mimics, α‐keto esters.
ChemInform Abstract: Iron(III) Chloride/Diorganyl Diselenides: A Tool for Intramolecular Cyclization of Alkynone O‐Methyloximes.
Authors: Speranca Adriane , Godoi Benhur , Zeni Gilson
Published: June 2013

A new, efficient, and environmentally friendly method allows the preparation of 4‐organoselenylisoxazoles.
ChemInform Abstract: Red‐Emitting Materials Derived from 2,3‐Dicyanopyrazine for Organic Light Emitting Devices
Authors: Jang Chun Keun , Song Cheol Jun , Park Ji Hyun , Yao Wang , Jaung Jae Yun
Published: June 2013

design, synthesis, and optical properties of dicyanopyrazine oriented fluorescent styryl dyes (I)
ChemInform Abstract: Inhibitory Effect on NO Production of Triterpenes from the Fruiting Bodies of Ganoderma lucidum.
Authors: Tung Nguyen The , Cuong To Dao , Hung Tran Manh , Lee Jeong Hyung , Woo Mi Hee , Choi Jae Sue , Kim Jaewang , Ryu Sung Ho , Min Byung Sun
Published: June 2013

Four new lanostane triterpenes, butyl lucidenate P (I), butyl lucidenate D2 (II), butyl lucidenate E2 (III), and butyl lucidenate Q (IV), are isolated along with eleven known compounds from the fruiting bodies of Ganoderma lucidum.
ChemInform Abstract: Bioactive Polyhydroxylated Steroids from the Hainan Soft Coral Sinularia depressa Tixier‐Durivault
Authors: Liang Lin‐Fu , Wang Xu‐Jie , Zhang Hai‐Yan , Liu Hai‐Li , Li Jia , Lan Le‐Fu , Zhang Wen , Guo Yue‐Wei
Published: June 2013

isolation, structural determination and antibacterial activity of two new steroids (I) and (II) together with 13 known analogues
ChemInform Abstract: Five New Phenolic Glycosides from Hedyotis scandens
Authors: Wang Guo‐Cai , Li Tao , Deng Fang‐Ye , Li Yao‐Lan , Ye Wen‐Cai
Published: June 2013

isolation, structure determination and anti‐RSV activity of new phenolic glycosides, hedyotosides A—E (I), (II), (III)
ChemInform Abstract: The Interlayer Exchange Interaction in Multilayer Magnetic Systems Fe/Cr/Fe (Review Article)
Authors: Kreines N. M. , Kholin D. I. , Demokritov S. O.
Published: June 2013

Review: 50 refs.
ChemInform Abstract: Applications of in situ Synchrotron XRD in Hydrometallurgy: Literature Review and Investigation of Chalcopyrite Dissolution
Authors: Majuste D. , Ciminelli V. S. T. , Eng P. J. , Osseo‐Asare K.
Published: June 2013

Review: 94 refs.
ChemInform Abstract: Medium and High Oxidation State Metal/Non‐Metal Fluoride and Oxide—Fluoride Complexes with Neutral Donor Ligands
Authors: Benjamin Sophie L. , Levason William , Reid Gillian
Published: June 2013

Review: 429 refs.
ChemInform Abstract: Stereogenic Metal Centers — From Werner to Supramolecular Chemistry
Authors: Constable Edwin C.
Published: June 2013

Review: 58 refs.
ChemInform Abstract: Building on Architectural Principles for Three‐Dimensional Metallosupramolecular Construction
Authors: Smulders Maarten M. J. , Riddell Imogen A. , Browne Colm , Nitschke Jonathan R.
Published: June 2013

Review: 93 refs.
ChemInform Abstract: Periodic Mesoporous Organosilicas: From Simple to Complex Bridges; a Comprehensive Overview of Functions, Morphologies and Applications
Authors: Van Der Voort Pascal , Esquivel Dolores , De Canck Els , Goethals Frederik , Van Driessche Isabel , Romero‐Salguero Francisco J.
Published: June 2013

Review: 328 refs.
ChemInform Abstract: Catalytic Activation of Olefins by Metal Triflates and Triflimides: Application to Fragrance Chemistry
Authors: Lemiere Gilles , Dunach Elisabet
Published: June 2013

Review: 61 refs.
ChemInform Abstract: The Synthesis of Bcr‐Abl Inhibiting Anticancer Pharmaceutical Agents Imatinib, Nilotinib and Dasatinib
Authors: Deadman Benjamin J. , Hopkin Mark D. , Baxendale Ian R. , Ley Steven V.
Published: June 2013

Review: 123 refs.
ChemInform Abstract: Catalytic Carbon—Boron Bond Formation via Activation of Alkane C—H Bonds
Authors: Bae Chulsung
Published: June 2013

Review: 60 refs.
ChemInform Abstract: Synthetic Strategies for Thiazoloquinoxalines and Their Applications
Authors: Abdel‐Wahab Bakr F. , Mohamed Hanan A. , El‐Mansy Mohamed F.
Published: June 2013

Review: 60 refs.
ChemInform Abstract: Alkane Functionalization via Electrophilic Activation
Authors: Labinger Jay A.
Published: June 2013

Review: 162 refs.
ChemInform Abstract: Development of Asymmetric Reactions Catalyzed by Chiral Organotin—Alkoxide Reagents
Authors: Yanagisawa Akira , Yoshida Kazuhiro
Published: June 2013

Review: 79 refs.
ChemInform Abstract: Recent Advances in the Development of 1,8‐Naphthalimide‐Based DNA‐Targeting Binders, Anticancer and Fluorescent Cellular Imaging Agents
Authors: Banerjee Swagata , Veale Emma B. , Phelan Caroline M. , Murphy Samantha A. , Tocci Gillian M. , Gillespie Lisa J. , Frimannsson Daniel O. , Kelly John M. , Gunnlaugsson Thorfinnur
Published: June 2013

Review: ca. 150 refs.
ChemInform Abstract: Template Synthesis of Molecular Knots
Authors: Ayme Jean‐Francois , Beves Jonathon E. , Campbell Christopher J. , Leigh David A.
Published: June 2013

Review: 76 refs.
ChemInform Abstract: Metal Coordination in Photoluminescent Sensing
Authors: Liu Zhipeng , He Weijiang , Guo Zijian
Published: June 2013

Review: 206 refs.
ChemInform Abstract: Halogen Bonding in Solution: Thermodynamics and Applications
Authors: Beale Thomas M. , Chudzinski Michael G. , Sarwar Mohammed G. , Taylor Mark S.
Published: June 2013

Review: 62 refs.
ChemInform Abstract: Production and Regulation of Levels of Amidated Peptide Hormones
Authors: Cao Feihua , Easton Christopher J.
Published: June 2013

Review: 121 refs.
ChemInform Abstract: Blocking Formation of Large Protein Aggregates by Small Peptides
Authors: Chang Yi‐Pin , Chu Yen‐Ho
Published: June 2013

Review: 61 refs.
ChemInform Abstract: Organic Stereochemistry. Part 4. Isomerisms about Single Bonds and in Cyclic Systems
Authors: Testa Bernard , Vistoli Giulio , Pedretti Alessandro
Published: June 2013

Review: ca. 150 refs.
ChemInform Abstract: Physical Studies of Heterometallic Rings: An Ideal System for Studying Magnetically‐Coupled Systems
Authors: Timco Grigore A. , McInnes Eric J. L. , Winpenny Richard E. P.
Published: June 2013

Review: 38 refs.
ChemInform Abstract: In situ Spectroscopic Detection of Active Surface Species in Asymmetric Heterogeneous Catalysis
Authors: Goubert Guillaume , McBreen Peter H.
Published: June 2013

Review: 15 refs.
Ammonia Recovery from Industrial Wastewater by TransMembraneChemiSorption
Authors: Ulbricht Martin , Schneider Jürgen , Stasiak Maria , Sengupta Amit
Published: June 2013

Membrane technology is a growing alternative for ammonia removal and recovery from wastewater compared to many other water treatment processes, such as strippers, scrubbers, and deaeration systems. Among the available alternatives, the TransMembraneChemiSorption (TMCS) has been gaining consideration, especially under certain operating conditions. TMCS using a membrane contactor is a unique separation process that is transitioning from research and pilot phases to field installations. This paper reviews the results of such an ammonia removal system using membrane contactors.
Selective and Brain‐Permeable Polo‐like Kinase‐2 (Plk‐2) Inhibitors That Reduce α‐Synuclein Phosphorylation in Rat Brain
Authors: Aubele Danielle L. , Hom Roy K. , Adler Marc , Galemmo Robert A. , Bowers Simeon , Truong Anh P. , Pan Hu , Beroza Paul , Neitz R. Jeffrey , Yao Nanhua , Lin May , Tonn George , Zhang Heather , Bova Michael P. , Ren Zhao , Tam Danny , Ruslim Lany , Baker Jeanne , Diep Linnea , Fitzgerald Kent , Hoffman Jennifer , Motter Ruth , Fauss Donald , Tanaka Pearl , Dappen Michael , Jagodzinski Jacek , Chan Wayman , Konradi Andrei W. , Latimer Lee , Zhu Yong L. , Sham Hing L. , Anderson John P. , Bergeron Marcelle , Artis Dean R.
Published: June 2013

Polo‐like kinase‐2 (Plk‐2) has been implicated as the dominant kinase involved in the phosphorylation of α‐synuclein in Lewy bodies, which are one of the hallmarks of Parkinson’s disease neuropathology. Potent, selective, brain‐penetrant inhibitors of Plk‐2 were obtained from a structure‐guided drug discovery approach driven by the first reported Plk‐2–inhibitor complexes. The best of these compounds showed excellent isoform and kinome‐wide selectivity, with physicochemical properties sufficient to interrogate the role of Plk‐2 inhibition in vivo. One such compound significantly decreased phosphorylation of α‐synuclein in rat brain upon oral administration and represents a useful probe for future studies of this therapeutic avenue toward the potential treatment of Parkinson’s disease.
Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus
Authors: Eagleson Kathie L. , Milner Teresa A. , Xie Zhihui , Levitt Pat
Published: June 2013

MET, a replicated autism risk gene, encodes a pleiotropic receptor tyrosine kinase implicated in multiple cellular processes during development and following injury. Previous studies suggest that Met modulates excitatory synapse development in the neocortex and hippocampus, although the underlying mechanism is unknown. The peak of Met expression corresponds to the period of process outgrowth and synaptogenesis, with robust expression in hippocampal and neocortical neuropil. Resolving whether neuropil expression represents presynaptic, postsynaptic or glial localization provides insight into potential mechanisms of Met action. The subcellular distribution of Met was characterized using complementary ultrastructural, in situ proximity ligation assay (PLA), and biochemical approaches. At postnatal day (P) 7, immunoelectron microscopy revealed near‐equivalent proportions of Met‐immunoreactive pre‐ (axons and terminals) and postsynaptic (dendritic shafts and spines) profiles in the stratum radiatum in the hippocampal CA1 region. Staining was typically in elements in which the corresponding pre‐ or postsynaptic apposition was unlabeled. By P21, Met‐immunoreactive presynaptic profiles predominated and ∼20% of Met‐expressing profiles were glial. A different distribution of Met‐immunoreactive profiles was observed in layer V of somatosensory cortex: Met‐labeled spines were rare and a smaller proportion of glial profiles expressed Met. Strikingly, Met‐immunoreactive presynaptic profiles predominated over postsynaptic profiles as early as P7. PLA analysis of neurons in vitro and biochemical analysis of tissue subsynaptic fractions confirmed the localization of Met in specific synaptic subcompartments. The study demonstrates that Met is enriched at synapses during development and its activation may modulate synapse formation and stability through both pre‐ and postsynaptic mechanisms. J. Comp. Neurol. 521:3241–3259, 2013. © 2013 Wiley Periodicals, Inc.
Quantitative analysis of ribbons, vesicles, and cisterns at the cat inner hair cell synapse: Correlations with spontaneous rate
Authors: Kantardzhieva Albena , Liberman M. Charles , Sewell William F.
Published: June 2013

Cochlear hair cells form ribbon synapses with terminals of the cochlear nerve. To test the hypothesis that one function of the ribbon is to create synaptic vesicles from the cisternal structures that are abundant at the base of hair cells, we analyzed the distribution of vesicles and cisterns around ribbons from serial sections of inner hair cells in the cat, and compared data from low and high spontaneous rate (SR) synapses. Consistent with the hypothesis, we identified a “sphere of influence” of 350 nm around the ribbon, with fewer cisterns and many more synaptic vesicles. Although high‐ and low‐SR ribbons tended to be longer and thinner than high‐SR ribbons, the total volume of the two ribbon types was similar. There were almost as many vesicles docked at the active zone as attached to the ribbon. The major SR‐related difference was that low‐SR ribbons had more synaptic vesicles intimately associated with them. Our data suggest a trend in which low‐SR synapses had more vesicles attached to the ribbon (51.3 vs. 42.8), more docked between the ribbon and the membrane (12 vs. 8.2), more docked at the active zone (56.9 vs. 44.2), and more vesicles within the “sphere of influence” (218 vs. 166). These data suggest that the structural differences between high‐ and low‐SR synapses may be more a consequence, than a determinant, of the physiological differences. J. Comp. Neurol. J. Comp. Neurol. 521:3260–3271, 2013. © 2013 Wiley Periodicals, Inc.
Cyto‐ and receptor architecture of area 32 in human and macaque brains
Authors: Palomero‐Gallagher Nicola , Zilles Karl , Schleicher Axel , Vogt Brent A.
Published: June 2013

Human area 32 plays crucial roles in emotion and memory consolidation. It has subgenual (s32), pregenual (p32), dorsal, and midcingulate components. We seek to determine whether macaque area 32 has subgenual and pregenual subdivisions and the extent to which they are comparable to those in humans by means of NeuN immunohistochemistry and multireceptor analysis of laminar profiles. The macaque has areas s32 and p32. In s32, layer IIIa/b neurons are larger than those of layer IIIc. This relationship is reversed in p32. Layer Va is thicker and Vb thinner in s32. Area p32 contains higher kainate, benzodiazepine (BZ), and serotonin (5‐HT)1Abut lower N‐methyl‐D‐aspartate (NMDA) and α2receptor densities. Most differences were found in layers I, II, and VI. Together, these differences support the dual nature of macaque area 32. Comparative analysis of human and macaque s32 and p32 supports equivalences in cyto‐ and receptor architecture. Although there are differences in mean areal receptor densities, there are considerable similarities at the layer level. Laminar receptor distribution patterns in each area are comparable in the two species in layers III–Va for kainate, NMDA, γ‐aminobutyric acid (GABA)B, BZ, and 5‐HT1Areceptors. Multivariate statistical analysis of laminar receptor densities revealed that human s32 is more similar to macaque s32 and p32 than to human p32. Thus, macaque 32 is more complex than hitherto known. Our data suggest a homologous neural architecture in anterior cingulate s32 and p32 in human and macaque brains. J. Comp. Neurol. 521:3272–3286, 2013. © 2013 Wiley Periodicals, Inc.
A distributed approach to network anomaly detection based on independent component analysis
Authors: Palmieri Francesco , Fiore Ugo , Castiglione Aniello
Published: June 2013

Network anomalies, circumstances in which the network behavior deviates from its normal operational baseline, can be due to various factors such as network overload conditions, malicious/hostile activities, denial of service attacks, and network intrusions. New detection schemes based on machine learning principles are therefore desirable as they can learn the nature of normal traffic behavior and autonomously adapt to variations in the structure of ‘normality’ as well as recognize the significant deviations as suspicious or anomalous events. The main advantages of these techniques are that, in principle, they are not restricted to any specific environment and that they can provide a way of detecting unknown attacks. Detection performance is directly correlated with the traffic model quality, in terms of ability of representing the traffic behavior from its most characterizing internal dynamics. Starting from these ideas, we developed a two‐stage anomaly detection strategy based on multiple distributed sensors located throughout the network. By using Independent Component Analysis, the first step, modeled as a Blind Source Separation problem, extracts the fundamental traffic components (the ‘source’ signals), corresponding to the independent traffic dynamics, from the multidimensional time series incoming from the sensors, corresponding to the perceived ‘mixed/aggregate’ effect of traffic on their interfaces. These components will be used to build the baseline traffic profiles needed in the second supervised phase, based on a binary classification scheme (detection is casted into an anomalous/normal classification problem) driven by machine learning‐inferred decision trees. Copyright © 2013 John Wiley & Sons, Ltd.
Effects of Oriented Surface Dipole on Photoconversion Efficiency in an Alkane/Lipid‐Hybrid‐Bilayer‐Based Photovoltaic Model System
Authors: Liu Lixia , Xie Hong , Bostic Heidi E. , Jin Limei , Best Michael D. , Zhang X. Peter , Zhan Wei
Published: June 2013

When a phospholipid monolayer containing a zinc‐coordinated porphyrin species formed atop a self‐assembled monolayer of heptadecafluoro‐1‐decanethiol (CF3(CF2)7(CH2)2SH) is subjected to photoelectrochemical current generation, a significant modulation effect is observed. Compared with devices that contain similar photoactive lipid monolayers but formed on 1‐dodecanethiol SAMs, these fluorinated hybrid bilayers produce a >60 % increase in cathodic currents and a similar decrease in anodic currents. Photovoltages recorded from these hybrid bilayers are found to vary in the same fashion. The modulation of photovoltaic responses in these hybrid‐bilayer‐based devices is explained by the opposite surface dipoles associated with the thiols employed in this study, which in one case (fluorothiol) increase and in another (alkanethiol) decrease the work function of the underlying gold substrates. A similar trend of photovoltage/photocurrent modulation is also observed if fullerene is used as the photoagent in these devices. Our results reveal the intricacy of orientated surface dipole in influencing the photovoltaic processes, and its subtle interplay with other factors related to the photoagents, such as their location and orientation within the organic matrix.
Enhanced Performance of p‐Type Dye‐Sensitized Solar Cells Based on Ultrasmall Mg‐Doped CuCrO2 Nanocrystals
Authors: Xiong Dehua , Zhang Wenjun , Zeng Xianwei , Xu Zhen , Chen Wei , Cui Jin , Wang Mingkui , Sun Licheng , Cheng Yi‐Bing
Published: June 2013

Herein, we present ultrasmall delafossite‐type Mg‐doped CuCrO2 nanocrystals prepared by using hydrothermal synthesis and their first application as photocathodes in efficient p‐type dye‐sensitized solar cells. The short‐circuit current density (Jsc) is notably increased by approximately 27 % owing to the decreased crystallite size and the enhanced optical transmittance associated with Mg doping of the CuCrO2 nanocrystalline sample. An open‐circuit voltage (Voc) of 201 mV, Jsc of 1.51 mA cm−2, fill factor of 0.449, and overall photoconversion efficiency of 0.132 % have been achieved with the CuCr0.9Mg0.1O2 dye photocathode sensitized with the P1 dye under optimized conditions. This efficiency is nearly three times higher than that of the NiO‐based reference device, which is attributed to the largely improved Voc and Jsc. The augmentation of Voc and Jsc can be attributed to the lower valance band position and the faster hole diffusion coefficient of CuCr0.9Mg0.1O2 compared to those of the NiO reference, respectively, which leads to a higher hole collection efficiency.