bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge on Sexually Transmitted Infections (STIs) and sexual practices among Nursing Trainees in Yendi Municipality, Northern Region of Ghana
Authors: Mutaru Abdul-Manaf , Asumah Mubarick , Ibrahim Mohammed , Sumaila Issah , Hallidu Mustapha , Mbemah Joachim , Atakole Baba , Zakaria Dawud
Published: November 2021

Purpose: This study aimed to assess the knowledge on Sexually Transmitted Infections (STIs) and sexual practices among nursing trainees in Yendi Municipality, Northern Ghana.

Methodology: The study was conducted in Northern Ghana, using a cross-sectional study design. The study recruited 265 students using a multistage sampling technique. A self-reported questionnaire was used for the data collection. Data were analyzed using Stata version 16 and p-value < 0.05 was considered statistically significant.

Findings: Majority (54.0%) of the respondents were males (69.1%), below 25 years with a mean age of 23.5 ±2.4 years. Most students (33.2%) had their first sexual relationship before 20 years of age. Only 20.4% of the students reported having had STIs in the past six months. Nine out of ten (90.9%) respondents have heard of STIs. Among the respondents who had ever heard of STIs, majority (71.7%) heard about STIs in school, followed by the media (41.1%), friends (33.2%), and relatives (29.4%).  Majority (75.0%) of students had sufficient knowledge of STIs. The association between knowledge on STIs and program of study (X2=7.6, p=0.023), gender (X2=3.93, p=0.047), and age (X2=22.3, p=0.039) were statistically significant. The odds of sufficient knowledge of STIs for students pursuing Registered Mental Nursing (RMN) is 3 times that of those studying RNAC program (AOR=3.4, 95%CI=1.23 – 9.55, p-value=0.019). Respondents aged ≥25 years were 1.8 times more likely to have sufficient knowledge compared with those below 25 years (AOR=1.8, 95%CI=0.91 – 3.38, p=0.047). 

Recommendation: There is the need for sensitizations and intensifying education since not all students were armed with the required information on STIs. Stakeholders including, the Ministry of Health, Ghana Health Service, Islamic Medical Association of Ghana (IMAGH), Christian Health Association of Ghana (CHAG) and Tutors of health training institutions ought to re-evaluate the current interventions, and protocols on STIs prevention. There is also the need to regulate media content on health by the National Media Commission and the Ministry of Health of Ghana and its affiliates to ensure the right information on STIs is channelled to listeners by qualified persons.
Построение усеченных таблиц «затраты-выпуск» для регионов России с использованием коэффициентов локализации
Authors: Пономарёв Ю.Ю. , Евдокимов Д.Ю.
Published: November 2021

В статье рассмотрены подходы к построению усеченных региональных таблиц «затраты-выпуск» и описана методология регионализации национальных таблиц межотраслевого баланса посредством методов, использующих коэффициенты локализации (SLQ, PLQ, CILQ, RLQ, FLQ, AFLQ, SFLQ). На основе изложенного подхода построены усеченные таблицы межотраслевого баланса для субъектов и федеральных округов РФ за 2017 г., с помощью которых, в свою очередь, рассчитаны оценки региональных отраслевых мультипликаторов социально-экономических эффектов для набора ключевых экономических показателей (валовый выпуск, валовая добавленная стоимость, совокупная занятость). Статья подготовлена в рамках выполнения научно-исследовательской работы государственного задания РАНХиГС.
Оценка взаимосвязи квалификационной структуры занятости и потребления домашних хозяйств с использованием таблиц «затраты-выпуск»
Authors: Единак Е.А. , Широв А.А.
Published: November 2021

В статье анализируется влияние изменения структуры занятости на экономическую динамику. Рассматриваются три ключевых направления: изменение квалификационной структуры занятых; изменение уровня заработной платы и доходов населения вследствие модернизации рабочих мест и роста производительности труда; изменение объемов и структуры расходов домашних хозяйств. Обосновывается, что снижение доли низкоквалифицированной рабочей силы в структуре занятости положительно повлияет на рост объемов и изменение структуры потребления домашних хозяйств, что в свою очередь является важнейшим фактором ускорения экономической динамики. Соответствующие расчеты получены на базе таблицы «затраты-выпуск», в которой детализированы строка ФОТ третьего квадранта до квалификационных групп занятых, а также столбец второго квадранта потребление домашних хозяйств до отдельных децильных групп.
Влияние мер государственной поддержки на сферу рекреации и туризма региона
Authors: Воробей Е.К.
Published: November 2021

В статье на примере Краснодарского края проанализировано взаимное влияние суммарной финансовой поддержки экономики региона (включающей в себя поступления из государственного бюджета, российские и иностранные инвестиции) и входящего в регион туристического потока. Анализ статистических данных за период с 2009 по 2019 г. показал наличие достоверных корреляций между темпами изменения финансовой поддержки и темпами изменения туристического потока. На основе выявленных корреляций предложены уравнения, которые можно использовать для прогнозирования изменений. Кроме того, в статье показано, что в послекризисный период полноценное восстановление сферы рекреации и туризма требует ежегодного увеличения суммарного финансового потока Краснодарского края на 15%.
Возможности технологической модернизации российской экономики
Authors: Комков Н.И. , Усманова Т.Х. , Сутягин В.В.
Published: November 2021

Рассматриваются возможности социально-экономического развития с учетом вклада в ВВП различных секторов экономики. Отмечается высокая доля ВВП добывающего сектора экономики, а также низкая доля обрабатывающего сектора. Рассмотрены ограничения роста перерабатывающих отраслей, отмечается недостаточное использование потенциала этого сектора. Показаны условия и ограничения согласованного развития разных секторов и способы преодоления этих ограничений.
Guidelines for Effectively Studying the Behavior of Leaders in the Tourism Sector Using Interactionism Model from a Strategic Management Perspective
Authors: Nantavisit Nuttaprachya , Wongsa Surasak
Published: November 2021

The interactionism model is strongly connected to the theory of leadership effectiveness as a secondary concept of psycho-behavioral science that is extensively used today to support leaders in various professions, including tourism management, implying that strategic leadership qualities are a behavior capable of adapting to change and guiding the organization to reach its highest goals. Hence, this article explains the theoretical relationship between the interactionism model, leadership effectiveness theory, and McKinsey 7s framework concepts in tourism management and proposes an integrated research framework as a guideline for Thai scholars to investigate leadership behavior in the future under the conditions of tourism management. This study suggests combining the two ideas using a structural model analysis (SEM) framework due to its findings. The situational leadership effectiveness is categorized as part of the interactionism model, which focuses on two dimensions of leadership behavior: LPC psychological element and situational governance. It has been augmented by leaders’ circumstances or the working environment because of the study's context-specific situations, namely, tourist management. Consequently, a connection between leadership and strategic management was discovered.
Patterns of Wisdom in Safavid Iran
Authors: Esots Janis
Published: November 2021

The exceptional intellectual richness of seventeenth-century Safavid Iran is epitomised by the philosophical school of Isfahan, and in particular by its ostensible founder, Mir Damad (d. 1631), and his great student MullaSadra (aka Sadr al-Din Shirazi, d. 1636). Equally important to the school is the apophatic wisdom of Rajab ‘Ali Tabrizi that followed later (d. 1669/70).

However, despite these philosophers’ renown, the identification of the ‘philosophical school of Isfahan’ was only proposed in 1956, by the celebrated French Iranologist Henry Corbin, who noted the unifying Islamic Neoplatonist character of some 20 thinkers and spiritual figures; this grouping has subsequently remained unchallenged for some fifty years.

In this highly original work, Janis Esots investigates the legitimacy of the term ‘school’, delving into the complex philosophies of these three major Shi’i figures and drawing comparisons between them. The author makes the case that MullaSadra’s thought is independent and actually incompatible with the thoughts of Mir Damad and Rajab Ali Tabrizi. This not only presents a new way of thinking about how we understand the ‘school of Isfahan’, it also identifies Mir Damad and Rajab Ali Tabrizi as pioneers in their own right.
Northern Irish Writing After the Troubles
Authors: Magennis Caroline
Published: November 2021

Winner of the British Association for Comtemporary Literary Stuides (BACLS) monograph prize

The period since the Good Friday Agreement in 1998 has seen a sustained decrease in violence and, at the same time, Northern Ireland has undergone a literary renaissance, with a fresh generation of writers exploring innovative literary forms.

This open access book explores contemporary Northern Irish fiction and how the ‘post’-conflict period has led writers to a renewed engagement with intimacy and intimate life. Magennis draws on affect and feminist theory to examine depictions of intimacy, pleasure and the body in their writings and shows how intimate life in Northern Ireland is being reshaped and re-written.

Featuring short reflective pieces from some of today’s most compelling Northern Irish Writers, including Lucy Caldwell, Jan Carson, Bernie McGill and David Park, this book provides authoritative insights into how a contemporary engagement with intimacy provides us with new ways to understand Northern Irish identity, selfhood and community.

The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on http://bloomsburycollections.com.
Trauma, Primitivism and the First World War
Authors: Porter Joy
Published: November 2021

This book examines the extraordinary life of Frank “Toronto” Prewett and the history of trauma, literary expression, and the power of self-representation after WWI.

Joy Porter sheds new light on how the First World War affected the Canadian poet, and how war-induced trauma or “shell-shock” caused him to pretend to be an indigenous North American. Porter investigates his influence of, and acceptance by, some of the most significant literary figures of the time, including Siegfried Sassoon, Edmund Blunden, Wilfred Owen and Robert Graves.

In doing so, Porter skillfully connects a number of historiographies that usually exist in isolation from one another and rarely meet. By bringing together a history of the WWI era, early twentieth century history, Native American history, the history of literature, and the history of class Porter expertly crafts a valuable contribution to the field.
Liability Insurance in International Arbitration
Authors: Jacobs Sir Richard , Masters Lorelie S , Stanley Paul
Published: November 2021

The Bermuda Form

This is the third revised edition of what was described by the English Court of Appeal in C v D as the ‘standard work’ on Bermuda Form excess insurance policies. The Form, first used in the 1980s, covers liabilities for catastrophes such as serious explosions or mass tort litigation and is now widely used by insurance companies. It is unusual in that it includes a clause requiring disputes to be arbitrated under English procedural rules in London but subject to New York substantive law. This calls for a rare mix of knowledge and experience on the part of the lawyers involved, each of whom is required to confront the many differences between English and US law and legal culture. In addition, since the awards of arbitrators are confidential and are not subject to the scrutiny of the courts, the book helps professionals understand the Form’s lengthy and complex provisions.

The book, first published in 2004, was the first comprehensive analysis of the Bermuda Form. It is frequently cited in Bermuda Form arbitrations and was the joint winner in 2012 of British Insurance Law Association Book Prize for the most notable contribution to literature in the field of law as it affects insurance. It offers a detailed commentary on how the Form is to be construed, its coverage, the substantive law to be applied, the limits of liability, exceptions, and, of course, the procedures to be followed during arbitration proceedings in London. The book will prove invaluable to lawyers, risk managers, and executives of companies which purchase insurance on the Bermuda Form, and to clients, lawyers or arbitrators involved in disputes arising therefrom.
Eglish Speaking Anxiety Level And Major Component Of Anxiety Of Undergraduate Engineering Students At Erode Sengunthar Engineering College, Tamil Nadu: A Descriptive Study
Authors:   Erode Sengunthar Engineering College., V Anbuchelvan Mr. Solomon , N. Mythili Lt. Dr. ,   Sri Vasavi college, Erode.
Published: November 2021

Speaking in English causes anxiety in learners’ mind and it acts as a filter. Anxiety impedes speaking in English which is a problem for the learners. This paper is intended to address the problem found in Erode Sengunthar Engineering College students. The study examines the level of anxiety and its major factor that filters the performance while speaking in English inside the classroom. 50 under graduate engineering students attended the study. For data collection a series of questionnaire of FLCAS developed by Horwitz in 1986, based on the Likert 5 point scale was administered. It also focuses on the performance of pupils most of whom feel more anxious about foreign language. The findings of this research reveals that more students are moderately affected . More importantly, the results show that students are extremely concerned about fear of negative evaluation (3.41) and the Exam Anxiety (3.27).
STEM CELLS IN REGENERATIVE MEDICINE: ACHIEVEMENTS AND PROSPECTS
Authors: Lyzikov A. N. , Osipov B. B. , Skuratov A. G. , Prizentsov A. A.
Published: November 2021

Purpose: to analyze achievements and prospects of the application of stem cells in regenerative medicine. Material and methods. We performed analytical review of national and foreign literature, Internet resources in PubMed and others dealing with the apоplication of stem cells in regenerative medicine. Results. Rich experience of experimental and clinical application of stem cells in the treatment of cardiovascular, neurological, endocrine, hematological, autoimmune, traumatological, and other diseases has been gained by now. Conclusion. Notwithstanding the success and achievements in regenerative medicine during the recent years, a lot of problems and questions remain unsolved. The application of both embryonic stem cells and postnatal stem cells has its pros and cons. The exact mechanism of the effect of transplanted stem cells remains unclear. It is necessary to study long-term effects of stem cell therapy (in particular, the risk of oncogenesis).
THE AGE DYNAMICS OF MULTIFACTOR EXPRESS INDICATORS of the functional STATE OF KAYAK AND CANOE ROWERS DURING TRAINING
Authors: Shtanenko N. I. , Budko L. A. , Sevostianov P. A.
Published: November 2021

Objective: to analyze the age dynamics of parameters of energy supply and functional state in kayak and canoe rowers during training. Material and methods: We examined 32 male sportsmen who were divided into 3 age groups (13-15, 16-18 and 19-21 years old). The functional state and the basic parameters of energy supply system of muscular activity of the sportsmen were evaluated by data of the computer program complexes «Omega-C» and «D-test» before and after training. Results: The data obtained make it possible to make a supposition that the age features of the parameters of aerobic capacity are closely interconnected with the resultant effect of vegetative regulation (TP waves), parasympathetic activity (HF waves) and especially sympathetic link, which is revealed in physical exercise (VLF, LF waves). Conclusion: the study revealed the degree of interconnection of functional and energetic parameters of the computer program complex «Omega-C» with the parameters of multifactor express-diagnostics by S. A. Dushanin with the use of the computer program complex «D-test». This method makes it possible to prognose organism reactions to physical exercise.
CHANGES OF STRESS HORMONES LEVELS AND SERUM LIPID SPECTRUM INDICATORS OF RATS IN ACUTE CEREBRAL ISCHEMIA
Authors: Chubukova T. N. , Ugolnick T. S.
Published: November 2021

Objective: to study the changes of stress hormones levels and serum lipid spectrum indicators of Wistar male rats in acute cerebral ischemia (ACI). Material and methods . The study was performed on 40 mature Wistar male rats weighing 220-300 g. ACI simulation was performed by means of 3-hour chronic occlusion of bilateral common carotid arteries (n = 23). The control group consisted of intact animals (n = 17). The levels of total cholesterol (TC, mmol/l), triglyceride (TG, mmol/l), high density lipoproteins (HDL, mmol/l), low density lipoprotein (LDL, mmol/l), lipoproteins of very low density (VLDL mmol/l), adrenocorticotropic hormone (ACTH nmol/l), and cortisol (nmol/l) were assessed in the serum of the rats. Atherogenic index (AI) was calculated according to the formula: AI = (TC-HDL) / HDL. Results. TC concentration in the serum of the rats of the experimental group was 1.1 times as high (p = 0.03), the concentration of TG - 1.2 times as high (p = 0.012), the concentration of VLDL - 2 times as high (p = 0.01), cortisol concentration - 1.4 times as high (p = 0.02) compared with the control group. The rats of the experimental group revealed a moderate inverse correlation between the levels of cortisol and index AI (p = 0.025). The group of ACI rats observed a tendency of direct relation of ACTH with TG and LDL serum, p > 0.05. The correlation of ACTH and serum triglycerides in the rats of the control group was statistically significant (p = 0.012). Conclusion: ACI during the period «therapeutic window» in rats is accompanied by a complex set of compensatory and adaptive reactions which may be characteristic of a generalized stress response.
THE EFFECT OF CITRUS PECTIN ON THE FUNCTIONAL STATUS OF RATS` COLON
Authors: Martsynkevich E. V. , Kondrasheva S. B. , Sedakova V. A. , Lukashenko T. M.
Published: November 2021

Objective: to study the effect of citrus pectin on the functional status of rats` colon. Material and methods. The experiments have been performed on male rats (n = 45) in accordance with the rules of the humane treatment of experimental animals. The doses of dietary fiber have been calculated by the physiological norm of human consumption, approved by the Committee on Health of the Russian Federation (2002) and accounted for 1.25 and 1.875 g/animal/day. Microbiological and biochemical studies have been carried out according to the conventional techniques. Results. It has been ascertained that long-term use (for 1 month) of citrus pectin at a dose of 1.25 g/animal/day leads to changes of the titer the positive microflora, but causes emergence of Citrobacter . The increase of pectin to 1.875 g/animal/day leads to a decrease in the concentration of specific probiotic microorganisms (Lactobacillus ssp. and Bifidobacterium ssp.), an increase in the pool of Enterobacteriaceae and potentially pathogenic Fungi. The material verified Citrobacter and Candida , which were not found in control animals. Applying both the doses of citrus pectin we noted an increase in the concentrations of acetic and butyric acids, acidification of the intestinal contents, as evidenced by the decrease in the pH of the animals` faeces. Conclusion. The experimental data make it possible to state that regular long-term consumption of citrus pectin at the permissible dose (1.25 g/animal/day) in the normal physiological state does not cause any changes in the probiotic intestinal flora but creates preconditions for enhancing colonization by opportunistic agents. The excess dose of the studied additive results in a significant decrease of pH values of the intestinal contents and enhanced proliferation of potentially pathogenic microorganisms.
THE AMBULANCE SERVICE OF GOMEL REGION OVER 1944-1950
Authors: Kapliyeva M. P. , Kapliyev A. A.
Published: November 2021

Research objective: to characterize the formation of the ambulance service in Gomel region during the first post-war years. The sources for the study were materials on the history of medicine (reports, orders, and reports of the Regional Public Health Department of Gomel region, the Ambulance station of the city of Gomel, the City Council of the People's Deputies and Party Bodies) from the State Archives of Gomel region and the State Archive of Public Associations of Gomel region.
THE APPLICATION OF COMPUTER CALCULATION OF MINIMALLY SUFFICIENT AREAS OF BONE RESECTION IN MICROSURGERY OF LUMBAR COMPRESSIVE SYNDROMES
Authors: Remov P. S. , Olizarovich M. V.
Published: November 2021

Objective: to define the main types of bone resection and geometric shapes of the bone window made by means of computer calculation, to estimate the effectiveness of the proposed method in the early postoperative period using the visual analog scale (VAS). Material and methods . 31 patients with compressive pathology of the lumbosacral spine were operated using the invented method of calculation in the years 2015-2016. The patients were surveyed, the case histories, protocols of X-ray computed tomography (X-ray CT) and magnetic resonance imaging (MRI) were analyzed. Results. Due to the application of the method, the intensity of radicular pains in the early postoperative period decreased in all the studied subgroups. According to the VAS scale, the pains in the subgroup of patients with herniated discs without sequestration decreased from 7.50 (6.00; 9.00) to 2.00 (1.00; 3.50) - p = 0.001, in the subgroup of herniated discs with sequestration - from 9.50 (7.25; 10.00) to 2.5 (1.25; 3.75) - p = 0.011, in the subgroup of herniated discs in combination with stenosis - from 8.00 (5.00; 9.50) to 2.00 (1.00; 3.50) - p = 0.008. Conclusion. The developed method of calculation of minimally sufficient areas of bone resection made it possible to perform economical, reasonable resection of the posterior supportive complex bone structures, besides it was used in different types of the compressive spine pathology.
THE HYGIENIC ASSESSMENT OF DIET OF CITY AND RURAL SCHOOL CHILDREN LIVING IN GOMEL REGION
Authors: Bortnovsky V. N. , Kozlovsky A. A. , Kozlovsky Al. Al.
Published: November 2021

The article considers the topical questions of a well-balanced diet of teenagers living in Gomel region. The dietary patterns of 220 city and rural school children at the age of 12-16 have been studied using the medical and social method (questioning). We have revealed significant shortcomings in the dietary patterns and quality of diet of the school children. We have found that the majority of the children do not follow the dietary pattern. The inadequate consumption of meat products, fish, diary products, and fruit by the school children affects their health and creates prerequisites for alimentation-dependent illnesses: every third child has dyspeptic complaints, every fifth child has already undergone out-patient treatment for the gastrointestinal diseases. Due to this, it is necessary to redouble the sanitary and educational and psychological and preventive work aimed at the leveling of the effect of the detected negative factors among teenagers.
A CASE OF DIROFILARIASIS IN THE UROLOGICAL PRACTICE
Authors: Kniaziuk A. S.
Published: November 2021

Human dirofilariasis is zoonotic, tissue, imaginal helminthiasis with vector-borne transmission. Over the last decades the prevalence of dirofilariasis has been rising, the invasion area has been increasing and moving further into Republic of Belarus. Its clinical manifestations are different, but dirofilariasis occurs rarely in the urological practice. The article presents a literature review of the etiology, pathogenesis, clinical symptoms, diagnostics, and treatment of dirofilariasis and describes a clinical case of dirofilariasis in the urological practice. The diagnosis has been confirmed histologically.
MEANS OF RATIONALIZATION OF THE MORPHOLOGICAL STUDIES OF THE DUODENUM
Authors: Kovalenko V. V.
Published: November 2021

The article gives the detailed description of some means of optimization of well-known morphological methods of the study of the duodenum with the use of computer technologies as well as detailed instructions on their realization. It notes the advantages of the developed means before the existing traditional morphological procedures and points out the prospects of their application during the study of not only the duodenum, but also other anatomical formations.
OBSTETRICAL HEMATOMAS (clinical lecture, part I)
Authors: Teslova O. A.
Published: November 2021

The clinical lecture deals with topical emergency problem in obstetrical practice, i.e. hematomas of soft tissues of the birth canal. The first part of the lecture presents modern data on the epidemiology and etiopathogenesis, classification approaches, clinical manifestations, modern facilities for diagnosis and treatment of obstetrical hematomas of different localization. The second part of the lecture will describe and analyze clinical cases of hematomas of the birth canal that occurred at maternity hospitals of Gomel region, as well as rare cases of obstetric hematomas according to foreign publications. The third part of the lecture will present data on health status of children whose mothers developed obstetrical hematomas during their delivery.
VEGETATIVE REGULATION OF CARDIAC FUNCTION IN DIFFUSE TOXIC GOITER ASSOCIATED WITH PATHOGENETIC THERAPY
Authors: Tsitko E. V. , Маlауеvа Е. G. , Yatsenko I. P. , Tsitko E. L. , Hudyakov I. A.
Published: November 2021

Objective: to study the vegetative regulation of cardiac function by means of Holter monitoring in patients diagnosed with diffuse toxic goiter associated with therapy with tireostatics and beta adrenoblockers (рropranololum, bisoprolol). Material and methods . 82 patients diagnosed with a diffuse toxic goiter aged 18-60, out of them 24 men and 58 women participated in the study. The patients were divided into two groups: the first group (46 patients) took non-selective beta adrenoblocker Propranololum (Anaprilin), the second group (36 patients) took beta1-adrenoblocker Bisoprolol. The control group included 30 almost healthy volunteers. All the patients were performed Holter monitoring with the assessment of heart rate variability, their thyroid status was studied. Results. We have done the comparative analysis of the thyroid status in the groups of the patients with diffuse toxic goiter following different schemes of pathogenetic therapy. We have analyzed the data of Holter monitoring with the assessment of heart rate variability related to the intake of cardioselective and non-selective beta adrenoblockers. Conclusion . Patients with compensated thyrotoxicosis taking Bisoprolol at a dose of 5 mg/day and Thiamazolum of 15 mg/day have signs of vegetative imbalance in the form of dominance of sympathetic section of the vegetative nervous system. When the compensation of thyrotoxicosis is achieved in patients using the scheme of 40 mg/day of Anaprilin and 20mg/day of Thiamazolum, the vegetative regulation of cardiac function is characterized by vegetative balance. The correction of medicamentous therapy of vegetative imbalance is possible taking into account results of Holter monitoring.
BLOOD PRESSURE IN SCHOOL AGE CHILDREN DEPENDING ON CIRCADIAN RHYTHMS
Authors: Nechytailo D. Yu. , Nechytailo Yu. N. , Kovtyuk N. I.
Published: November 2021

Objective: to assess the 24 hours fluctuations of blood pressure in school age children by ambulatory blood pressure monitoring Material and methods. 45 children of school age were examined. Daily blood pressure monitoring was performed in the hospital using the device Ambulatory Blood Pressure Monitor Holter ABPM50. Results. Among the surveyed children normal circadian index had only two patients (1.28 and 1.32 i.u.). The remaining patients had rigid circadian rate (less than 1.2 i.u.), which may indicate the presence of vegetopathology and violation of both afferent and efferent chains of vagosympatic regulation of heart rate, the phenomenon of «denervated» heart
THE application of polymer radioabsorbing materials TO SOLVE THE problem of electromagnetic safety
Authors: Bannyi V. A. , Ignatenko V. A.
Published: November 2021

Objective: to develop and create new absorbers of microwave radiation on polymer basis; to assess the perspectives of application of polymer composite radioabsorbing materials (RAM) and electromagnetic screens (EMS) for solving of the problem of electromagnetic ecology and electromagnetic protection of biological objects. Material and methods. Monolithic, fibrous and combined RAM based on filled thermoplastics were chosen as subjects of the study. Dielectric, magnetic and electroconducting substances different in nature, shape, size and a phase state were used as a filler. The RAM structure was study with means of a scanning electronic microscope. Results and discussion. The application of polymer composite materials for protection of biological objects from the effect of microwaves has been shown as efficient. The prospects for creation of polymer RAM, containing biodegradable components, nanoparticles, chiral structures, encapsulated liquids and also as non-woven RAM and polymers with own electroconductive have been analysed. Conclusion. RAM based on polymer composite thermoplastics and EMS are highly effective means for solving the problems of electromagnetic ecology.
UDDEN CARDIAC DEATH IN CHILDREN AND ADOLESCENTS: PREDICTORS, PROBLEMS OF DIAGNOSIS (literature review)
Authors: Krivelevich N. B.
Published: November 2021

The review presents information about the most common causes of sudden cardiac death in children and adolescents, predictors of sudden cardiac death in these diseases, modern methods of examination of patients threatened by the development of sudden cardiac death.
THE FUNCTIONAL STATUS OF NEUTROPHILS IN PATIENTS WITH CHRONIC RECURRENT INFECTIONS OF VARIOUS ETIOLOGY
Authors: Gusakova N. V. , Novikova I. A.
Published: November 2021

Objective: complex assessment of the functional status of neutrophils in patients with chronic recurrent furunculosis (CRF) and recurrent herpetic infection (RHI). Material and methods. We have studied the functional status of neutrophils: ROS-, NO-production and NET-generation, apoptosis, phagocytosis, and bactericidal ability of 103 patients with CRF and 238 patients with RHI examined during remission and exacerbation stages. Conclusion. The patients examined during remission showed the same type of the functional status changes of neutrophils in comparison with healthy individuals. The exception was the parameters of the bactericidal activity of neutrophils decreased in the patients with CRF. During the acute stage we marked the maximum changes of netosis and apoptosis. We have defined the possibility of using these data for more precise differentiation of exacerbation and remission in patients with CRF and RHI.
THE DIAGNOSTIC VALUE OF DIFFERENCES IN THE INTENSITY OF DYSTROPHIC CHANGES OF CENTRAL AND PERIPHERIC AREAS OF ILIOLUMBAR, LONG DORSAL, SACROILIAC AND SACROTUBEROUS LIGAMENTS
Authors: Yurkovskiy A. M. , Nazarenko I. V. , Achinovich S. L.
Published: November 2021

Objective: to determine the intensity of age-related dystrophic changes in different areas of iliolumbar, long dorsal sacroiliac ligament, and sacrotuberous ligaments. Materials. We have studied iliolumbar and long dorsal sacroiliac ligaments of 81 corpses: 39 men (the average age was 62.6 ± 8.8) and 20 women (the average age was 58.0 ± 11.8) and sacrotuberous ligaments of 15 male corpses (the average age was 69.2 ± 5.8) and 10 women (the average age was 57.8 ± 11.9). Results. We have revealed statistically significant differences between the parameters characterizing the intensity of dystrophic changes in the central and peripheral areas (i.e. in the areas adjacent to enthesitis) of iliolumbar, long dorsal sacroiliac and sacrotuberous ligaments. There was a strong relation between the age and intensity of dystrophic changes in various areas of iliolumbar, long dorsal sacroiliac, and sacrotuberous ligaments. Conclusion. Dystrophic changes in the iliolumbar, long dorsal sacroiliac and sacrotuberous ligaments develop unevenly in different parts (earlier and more pronounced changes appear in the areas adjacent to enthesis); age-related dystrophic changes of iliolumbar, long dorsal sacroiliac and sacrotuberous ligaments are closely linked, and therefore any changes that break this rule (for example, the emergence of asymmetrical expression or localization changes) are appropriate to consider as a potential pathological substrate of the lower back pain.
THE MECHANISM OF ENDOTHELIAL DYSFUNCTION FORMATION IN YOUNG PATIENTS WITH SPONDYLOGENIC VERTEBROBASILAR INSUFFICIENCY
Authors: Nekrasova N. A. , Tovazhnyanskaya E. L. , Galinovskaya N. V. , Tsukanov A. N.
Published: November 2021

Objective: to determine the type of changes of shear stress in vessels of the vertebrobasilar system in patients of young age with spondylogenic vertebrobasilar insufficiency (SVI). Material and methods. We examined 131 patients (70 women and 61 men) aged 18-40 (average age was 29.8 ± 3.8) with manifestations of spondylogenic vertebrobasilar insufficiency associated with muscular reflex, neurovascular and radicular syndromes of osteochondrosis of the cervical part of the vertebral column. 25 healthy donors made the control group. All the patients underwent radiological examination of the cervical part of the vertebral column with functional probes, doppler and duplex ultrasound of vessels of the neck and arteries of the head with functional probes; we performed the detection of endothelin-1, nitric oxide (NO) of blood serum. The changes of the shear stress in vessels of the vertebrobasilar system were assessed analyzing the Stuart index (ISD), systolic and diastolic parameter. Results. It has been found that development of spondylogenic vertebrobasilar insufficiency is accompanied by signs of endothelial dysfunction (ED), which is characterized by increased concentration of endothelin-1 related to the reduction of active metabolite of nitrogen oxide - S-NO. One of the mechanisms of ED in this cohort of patients is changes of the shear stress. Conclusion. In order to predict the development of ED in patients with spondylogenic vertebrobasilar insufficiency, it is recommended to pay particular attention to the state of the vascular wall.
THE EFFECTS OF CHRONIC STRESS ON THE MORPHOLOGICAL CHARACTERISTICS OF TESTICULAR TISSUES OF WISTAR RATS
Authors: Kidun K. A. , Solodova E. K. , Ugolnik T. S.
Published: November 2021

Stress has an unfavorable effect on male reproductive system. The aim of the work was to study the morphological changes in testicular tissues of Wistar rats in chronic stress according to Ortiz. We detected hyperemia of vessels, reduction of the diameter of seminiferous tubules, exfoliation of the seminiferous epithelium from the basement membrane, and also destructive changes in the seminiferous epithelium including development of necrosis in the testis of the rats after stress.
SOMATOMETRIC PARAMETERS OF SCHOOL CHILDREN LIVING IN AREAS WITH DIFFERENT LEVELS OF URBANIZATION
Authors: Kozakevich N. V. , Melnik V. A.
Published: November 2021

The article presents the results of the analysis of somatometric parameters of school children living in areas with different levels of urbanization. As a result of the carried out study we have proved the absence of any significant difference (р > 0.05) between somatometric parameters (body length, body mass and chest circumference) in city school children from big industrial cities. At the same time, the studied parameters revealed statistically significant differencies in school children of the same age from cities with high and medium levels of urbanization, as well as rural and city school children from big industrial centers.
DIFFUSE PULMONARY OSSIFICATION
Authors: Buinevich I. V. , Sverzh Zh. E. , Kuzmich M. V. , Karpeko A. G. , Shtilman M. E. , Loginov R. A.
Published: November 2021

Diffuse pulmonary ossification is a rare form of interstitial lung disease. Specific symptoms are often lacking. The present article describes a case of diffuse pulmonary ossification in an elderly person.
MYOCARDIALBRIDGINGOFA CORONARYARTERY
Authors: Kravchenko A. M. , Malayeva E. G. , Tsyrulnikova A. N. , Hudyakov I. A. , Dmitrienko A. A. , Kobruseva L. A. , Mistyukevich A. P. , Konovkova E. V. , Demidova V. O.
Published: November 2021

Myocardial (muscle) bridges are a common congenital anomaly of coronary arteries which is characterized by running of a coronary artery segment under the myocardial layer. According to literary data, the most frequent localization of myocardial bridges is observed in the middle segment of the anterior interventricular branch. In the majority of cases, the presence of a muscular bridge is not accompanied by clinical manifestations, and patients have a favorable long-term prognosis.Under certain circumstances, the course of the intramural course of the coronary artery may be accompanied by development of acute coronary syndrome, a sudden cardiac death. The main method of the diagnosis is coronary angiography. The article presents brief data on the prevalence, clinical picture, diagnosis, treatment of patients with myocardial bridges. Also, it describes a clinical case of a patient havinga myocardial bridge in the middle segment of the anterior interventricular branch with characteristic clinical symptoms confirmed by tool research methods.
THROMBOCYTOPENIA IN NEW-BORN BABIES
Authors: Sheybak L. N.
Published: November 2021

The article presents a review of literature on the etiology, pathogenesis and basic forms of thrombocytopenia, as well as their diagnostic algorithms and main approaches to treatment.
THE EXPERIENCE OF APPLICATION OF INFLIXIMAB IN THE TREATMENT OF AN ADOLESCENT WITH CROHN'S DISEASE
Authors: Lozovik S. K. , Latoho T. A. , Hmylko L. A.
Published: November 2021

Crohn's disease is a chronic disease which is characterized by severe progressive course, worsens the quality of life, leads to disability at a young age, which requires the development of new methods of treatment and introduction of modern highly effective medicines into practical health care. This article describes a case when infliximab was applied for the first time in the treatment of a patient with Crohn's disease in the Children's Gastroenterology Department of Gomel Regional Specialized Clinical Hospital.
THE LEVELS OF SOME CHEMOKINES IN THE BLOOD SERUM OF PATIENTS WITH EXACERBATION OF CHRONIC PURULENT RHINOSINUSITIS
Authors: Nakonechnaya O. A. , Onischenko A. I. , Gorbach T. V. , Tkachenko A. S. , Chubukova T. N.
Published: November 2021

Aim: to study the levels of fractalkine and IL-8 in blood serum of patients with exacerbation of chronic purulent rhinosinusitis. Material and methods . Twenty patients suffering from chronic purulent rhinosinusitis were examined during the stage of exacerbation. The control group consisted of twenty conditionally healthy individuals with nasal septum deviation. The blood sampling of the examined patients was performed. The levels of fractalkine and IL-8 in the blood serum were determined by ELISA. Results. The exacerbation of purulent chronic rhinosinusitis leads to increased levels of both fractalkine and IL-8 in the blood serum of patients, which contributes to the involvement of neutrophils, monocytes, and cytotoxic T-lymphocytes into the inflammatory process. Chemokines IL-8 and fractalkine play an important role in the pathogenesis of chronic purulent rhinosinusitis, which suggests the reasonability of application of pharmacological preparations that block their functions. Conclusions. The carried out study revealed increased levels of both fractalkine and IL-8 in the blood serum of the patients with chronic purulent rhinosinusitis at the stage of exacerbation
ANTIPHOSPHOLIPID SYNDROME
Authors: Makarenko E. V.
Published: November 2021

Antiphospholipid syndrome is autoimmune acquired thrombophilia associated with the formation of antibodies to phospholipids, which is manifested by recurrent venous or arterial thrombosis and/or pathology of pregnancy. Antiphospholipid antibodies are a heterogeneous group of autoantibodies interacting with phospholipids, which are components of cell membranes and phospholipid-binding proteins of blood plasma. Antiphospholipid syndrome can affect vessels of any caliber and localization, with thrombosis accompanied by no morphological signs of inflammation in the wall of the vessel. Obstetrical pathology is manifested by loss of the fetus, which can occur at any time of pregnancy, as well as other complications of pregnancy, such as preeclampsia and placental insufficiency. Based on the classification criteria, antiphospholipid syndrome is diagnosed if one of the clinical criteria (thrombosis or pregnancy complication) and one of the laboratory criteria including the lupus anticoagulant, antibodies to cardiolipin or β2-glycoprotein I, are revealed. The main tactic of the treatment of patients with antiphospholipid syndrome is to prevent thrombosis. For this purpose, the traditional therapy with anticoagulants and antiaggregants is applied. In addition, new medicines are being developed and evaluated
THE HYGIENIC EVALUATION OF CONTRIBUTION OF ENVIRONMENTAL OBJECTS TO FORMATION OF THE MICROELEMENT STATUS OF THE POPULATION
Authors: Romaniuk A. G.
Published: November 2021

The article presents literary data on studying of the interrelation of bio-elements in environmental objects and human body. The results of the study testify to the fact that diet and drinking water are the main sources of intake of trace elements into human body and that the features of formation of the microelement status of the population directly depend on their mineral structure.
MECHANIZATION OF SANITARY TRANSPORT AS A MAJOR FACTOR OF DEVELOPMENT OF THE AMBULANCE SERVICE IN THE SOVIET BELARUS (1919-1939)
Authors: Kapliyev A. A. , Kapliyeva M. P.
Published: November 2021

Objective : to study the main stages of development of sanitary transport and the impact of its mechanization on development of the ambulance service in the territory of the Soviet Belarus before the Second World War. Material and methods. The work has studied materials on history of medicine from the funds of state Belarusian and foreign archives. The analysis has been performed with the use of scientific and specialized historical research methods in accordance with the fundamental principles of historicism and objectivity. Results. The analysis has revealed the main factors that contributed to the development of the sanitary transport of the BSSR, as well as the main stages of its formation until the outbreak of the World War II. Conclusion. The most active modernization of the sanitary transport occurred in the second half of the 1930s, which precipitated the approach of professional emergency medical care to the population of the Soviet Belarus.
BODY COMPOSITION OF YOUNG ATHLETES ENGAGED IN CYCLIC SPORTS
Authors: Sukach E. S. , Budko L. A.
Published: November 2021

Objective: to study the parameters of body composition in young athletes engaged in cyclic sports. Material and methods. The differentiated parameters of body composition in young athletes have been revealed on the basis of the examination data of 60 cyclic athletes at the age of 13-15. The bioimpedance analyzer Medass AVS-01 was used for determination of the body composition parameters. Results. The performed bioimpedance analysis confirms specificity of the component body structure of young athletes engaged in cyclic sports. Conclusion. Thus the component body structure of the young athletes has been obtained by the results of the bioimpedance analysis. The majority of the body composition parameters of the examined athletes did not exceed the bounds of the normalized values. Statistically significant gender differences of the body composition features of young athletes doing cyclic sports have been found.
THE COMPARATIVE ANALYSIS OF THE AGE DYNAMICS OF SOMATOMETRIC PARAMETERS OF SCHOOL CHILDREN IN VARIOUS AREAS OF RESIDENCE
Authors: Kozakevich N. V.
Published: November 2021

Objective: to carry out the comparative analysis of the age dynamics of somatometric parameters of school children in various areas of residence. Material and methods. School children of comprehensive schools of Gomel aged 7-17 were the objects of the study. The program of the study included the measurement of body length, body mass, and chest circumference. The obtained material was compared to the corresponding literature data on the results of the examination of school children residing in other cities. Results. As a result of the study of the regularities of growth processes of the school children of Gomel, it has been found out that the periods of the maximum growth rates of body length, body mass, and chest circumference in boys were revealed before the onset of their puberty and by its end and in girls - only at the beginning of puberty in comparison with their peers in other areas of residence. Conclusion. The age dynamics of somatometric parameters of city school children depends on the area of their residence.
EWING’S SARCOMA
Authors: Shalyga I. F. , Achinovich S. L. , Kozlovskaya T. V. , Martemyanova L. A. , Turchenko S. Yu. , Avizhets Yu. N.
Published: November 2021

Ewing's sarcomas are rare neoplasms which comprise about 1% of all sarcomas. Сortical bones are usually affected. Cranial bones are rarely involved and are 1-6% of all Ewing's sarcoma cases. The article presents a case of a rare pathology - Ewing’s sarcoma of the temporal bone in a 36-year old woman and describes the morphological changes in the flat bones of the skull and the adjacent soft tissues of the head and their interconnection with data of clinical and laboratory and instrumental methods of investigation. Complexity of the lifetime diagnosis verification without histological and immunohistochemical confirmation has been shown on a concrete example.
EPIDEMIOLOGY OF THE MOST COMMON RISK FACTORS CAUSING THE DEVELOPMENT OF BLOOD CIRCULATION DISEASES AND THEIR CONTRIBUTION TO MORTALITY OF MALE ABLE-BODIED POPULATION
Authors: Cheshik I. A. , Sharshakova T. M.
Published: November 2021

The work presents an analytical survey of scientific publications on epidemiology of the most common risk factors contributing to the development of diseases of the circulatory system in the world and in the Republic of Belarus and focuses attention on their impact on mortality of population, first of all, of able-bodied males.
MOLECULAR AND GENETIC FACTORS FOR REALIZATION OF THE PATHOGENIC POTENTIAL OF HELICOBACTER PYLORI: PERSONIFIED TECHNIQUES FOR ASSESSMENT OF MANIFESTATIONS, LABORATORY DIAGNOSIS AND PROGNOSIS
Authors: Voropaev E. V.
Published: November 2021

The work presents an analytical review of features of techniques for assessment of the pathogenetic potential of Helicobacter pylori bacterium, an etiological agent of a number of gastrointestinal diseases. The main emphasis is laid on modern molecular and genetic techniques that make it possible to assess not only the pathogenic potential of the bacterium, but also the characteristics of the stomach microbiota and the infected human host`s genotype.