bluuebunny/crossref_metadata_2025 huggingface dataset:
Percutaneous nephrolithotomy or flexible ureteral lithotripsy, which one is better for patients with upper ureteral calculi of 1.5-2.0cm in diameter
Authors: Chen Wenpu , Hu Hengda , yu Guofeng
Published: July 2023

Purpose
To evaluate the clinical efficacy and safety of flexible ureteral lithotripsy (FURSL) and percutaneous nephrolithotomy (PCNL) in the treatment of upper ureteral impacted calculi (1.5cm to 2.0cm in diameter).
Methods
From December 2018 to October 2022, 104 patients with calculi in the upper ureter received percutaneous nephrolithotomy (PCNL)or flexible ureteroscopic lithotripsy (FURSL) in our institution. The clinical data of the patients in the two groups were retrospectively searched. Stone removal rate, operation time, blood loss, postoperative pain score, postoperative inflammatory factor, postoperative complication rates were compared between the two groups.
Results
A total of 104 patients were included in the study. The stone clearance rate and the secondary surgery rate were 88.89% and 7.41% in the FURSL group, the figures were 97.96% and 2.0% in the PCNL group (p=0.067, 0.198).Compared to patients in FURSL group, patients in the PCNL group had shorter operation time(PCNL 71.81±18.94minutes vs FURSL 86.80±22.49minutes, p=0.0004), fewer complications(PCNL 20.37% vs FURSL 6.12%), and lower postoperative inflammatory factor（p=0.0004）, yet they got more hemoglobin drop（PCNL 13.14±9.81g/L vs FURSL 4.77±3.55g/L, p<0.0001）, higher postoperative pain scores (p=0.0017) in the first three postoperative days.
Conclusion
Both FURSL and PCNL were effective methods for treating upper ureteral stones of 1.5-2.0cm in diameter given that there was an extremely high stone clearance rate and a very low secondary surgery rate. While PCNL effectively reduced operative time, postoperative inflammatory factor and the risk of postoperative complications, it had more hemoglobin drop and postoperative pain scores comparing with FURSL.
Geophysical studies of landslides by electrical resistivity tomography method located in Melekaboud village, Sarpolzahab city, Kermanshah province, Iran.
Authors: salami payam
Published: July 2023

This article focuses on geophysical studies conducted using the geoelectrical method in the vicinity of the Meleh Kaboud landslide near Sarpol Zahab city in Kermanshah province. Due to the extensive and inaccessible nature of the area, a comprehensive and detailed investigation of the region was deemed necessary. To accomplish this, 25 sections, each measuring 200 meters, were meticulously designed and surveyed using a dipole-dipole array. The geoelectric studies revealed that the landslide is situated at a relatively shallow depth, approximately 15 meters from the Earth's surface. Saturated layers with low resistance were identified in the geoelectric sections, indicating the presence of underground water or moist zones within the study area. The integrated image of the region was also examined, providing insights into the location of cracks and waterways. These findings were consistent with the results obtained through the inverse solution and were instrumental in the interpretation of the sections. Subsequently, the article presents a geological analysis of the area, followed by the presentation of results obtained using the dipole-dipole array. After interpreting the 2D sections, the article concludes by discussing the construction of a 3D model based on the obtained data.
Non-coding mutations at enhancer clusters contribute to pancreatic ductal adenocarcinoma
Authors: Wang Jun , Patel Minal , Maniati Eleni , Atanur Santosh , Pal Debosree , Rio-Machin Ana , Heward James , Kocher Hemant , Fitzgibbon Jude , Pradeepa Madapura
Published: July 2023

Non-coding mutations (NCMs) that perturb the function of cis-regulatory elements (CRE, enhancers) contribute to cancer. Due to the vast search space, mutation abundance and indirect activity of non-coding sequences, it is challenging to identify which somatic NCMs are contributing to tumour development and progression. Here, we focus our investigation on the somatic NCMs that are enriched at enhancers from 659 pancreatic ductal adenocarcinoma (PDAC) tumours. We identify cis-regulatory NCMs within PDAC-specific enhancers derived from high and low-grade PDAC cell lines and patient derived organoids using two independent computational approaches. Five such CREs enriched for PDAC associated NCMs are also frequently mutated in other common solid tumours. Functional validation using STARR-seq reporter assays enables the prioritisation of 43 NCMs (7.3%) from a pool of 587 NCMs with 6,082 oligos, that significantly alter reporter enhancer activity compared to wild-type sequences. CRISPRi perturbation of an enhancer cluster harbouring NCMs over long non-coding RNA gene MIR100HG, which hosts a microRNA cluster (mir100-let7a-2-125b-1), leads to the downregulation of MIR100HG accompanied by a significant reduction in the TGF-b pathway (known to induce MIR100HG) and other PDAC critical pathways, including KRAS, p53, MTOR and TNFa signalling. Collectively, we have reported here cis-regulatory NCMs in PDAC proximal to many cancer-relevant genes, and our integrated approach paves way to explore CRE-associated NCMs in other human cancer genomes.
Incidence and recovery of anterior cruciate ligament rupture combined with posterolateral tibial plateau fracture in the East China population: a 2-year follow-up study
Authors: Jiang Shijie , Ren Weizhi , Zhao Gongyin , Zhu Ruixia , Jia Xiaojun , Zheng Dong , Wang Yuji , Xu Wei
Published: July 2023

Objective: This study aimed to describe the incidence of ACL ruptures combined with posterolateral tibial plateau fractures in the East China population and evaluate the clinical outcomes of ACL reconstruction without treatment for posterolateral tibial plateau fracture at a 2-year follow-up.
Methods: Based on the inclusion criteria, the study included patients with ACL rupture or ACL avulsion fracture. MRI scans were reviewed to determine the incidence of ACL rupture combined with posterolateral tibial plateau fracture and concomitant injury. Clinical outcomes were evaluated using the SF-12 scale, the IKDC Subjective Knee Assessment Scale, the Lysholm Knee Rating Scale, the Tegner Activity Level Scale, and the KOOS score at a 2-year follow-up.
Results: 488 cases were enrolled, with 74.6% having noncontact injury mechanisms. Fractures with higher severity had a higher rate of meniscus damage, and patients with high-grade subtypes of fractures had a higher incidence of MCL tears than patients with low-grade fracture types. The Lysholm scores of the high-grade subtypes were 85.45 and 86.37, and the postoperative Tegner scores of the high-grade subtypes were 5.5. There were significant differences in functional recovery between patients with high-grade subtypes and patients with low-grade tibial plateau fractures.
Conclusions: The study found a high prevalence of displaced posterolateral tibial plateau impaction fractures in the setting of ACL tears, and they can be classified into distinct morphologic subtypes. The functional recovery of patients with high-grade subtypes of fractures is significantly lower than that of patients with low-grade injuries, suggesting that patients with high-grade injuries need surgical treatment to obtain satisfactory treatment results.
A Metallurgical Technology Investigation of the Wangxiangping Ancient Smelting Sites at Daye County
Authors: Pang Shuo , Li Chenyuan , Li Yanxiang
Published: July 2023

During the spring of 2022, an archaeo-metallurgical survey was conducted by the Beijing University of Science and Technology at the Wangxiangping site in Daye County. This subsequent testing excavation uncovered pottery and metal smelting relics from the Shang and Zhou dynasties. Charcoal samples extracted from the third stratification can be dated using 14C to as early as the late Shang Dynasty. The SEM-EDS method was employed to analyze the metallurgical relics found in each stratification layer of the site. The analysis revealed that pure copper smelting and tin bronze smelting activities coexisted at this location. Research results suggest that secondary copper oxide ore was used for reduction smelting, resulting in the production of red copper and high-grade 'white' matte. Additionally, tin ore was incorporated to create bronze, with tin serving as the alloy composition. However, no residual artifacts from casting activities were discovered. The survey and detection analysis conducted at this site offer significant evidence and data supporting further research into copper smelting activities in the Daye area during the Shang and Zhou dynasties.
A strong direct link from the layer 3/4 border to layer 6 of cat primary visual cortex
Authors: Martin Kevan A.C. , Sägesser Franziska D.
Published: July 2023

The cat primary visual cortex (V1) is a cortical area for which we have one of the most detailed estimates of the connection 'weights' (expressed as number of synapses) between different neural populations in different layers (Binzegger et al. 2004). Nevertheless, the majority of excitatory input sources to layer 6, the deepest layer in a local translaminar excitatory feedforward loop, was not accounted for by the known neuron types used to generate the quantitative Binzegger diagram. We aimed to fill this gap by using a retrograde tracer that would label neural cell bodies in and outside V1 that directly connect to layer 6 of V1.
We found that more than 80 % of labeled neurons projecting to layer 6 were within V1 itself. Our data indicate that a substantial fraction of the missing input is provided by a previously unidentified population of layer 3/4 border neurons, laterally distributed and connecting more strongly to layer 6 than the typical superficial layer pyramidal neurons considered by Binzegger and colleagues (2004).
This layer 3/4 to layer 6 connection may be a parallel route to the layer 3 – layer 5 – layer 6 feedforward pathway, be associated with the fast-conducting, movement-related Y pathway and provide convergent input from distant (5–10 degrees) regions of the visual field.
Financial Impact of Medication Reviews by Clinical Pharmacists to Reduce In-Hospital Adverse Drug Events: A Return-on-Investment Analysis
Authors: Jermini Mégane , Fonzo-Christe Caroline , Blondon Katherine , Milaire Christelle , Stirnemann Jérôme , Bonnabry Pascal , Guignard Bertrand
Published: July 2023

Backgrounds: Adverse drug events (ADEs) contribute to rising healthcare costs. Clinical pharmacists can reduce the risks of ADEs by preventing medication errors (MEs) through drug therapy optimization.
Aim: To build an economic model to reveal whether clinical pharmacists’ medication review (MR) activities were compensated by a reduction in healthcare costs associated with the prevention of potential ADEs.
Method: Pharmacists performed MR by solving drug-related problems (DRPs) to prevent ADEs during ward rounds in an internal medicine setting. First, avoided costs were estimated by monetizing five categories of DRPs (improper drug selection, drug interactions, untreated indications, inadequate dosages, and drug use without an indication). An expert panel assessed potential ADEs and their probabilities of occurrence for 20 randomly selected DRPs in each category. The costs of ADEs were extracted from internal hospital financial data. Second, a partial economic study in a hospital perspective, estimated the annual costs avoided through ADE prevention and the return on investment (ROI) of MR.
Results: The estimated annual cost avoided of the potential ADEs resulting from 676 DRPs detected was € 304,170. The cost of a 0.9 full-time equivalent (FTE) clinical pharmacist was € 112,408. Extrapolated to 1 FTE, the net saving per annum was € 213,069 or an ROI of 1 to 1.71. Sensitivity analyses showed the robustness of the economic model.
Conclusion: This economic model enabled to show the positive financial impact and favourable ROI of a MR intervention performed by clinical pharmacists. It should encourage the future deployment of a pharmacist-led ADE-prevention program.
LncRNA-mediated TPI1 and PKM2 promote self-renewal and chemoresistance in GBM
Authors: Yang Changxiao , Li Ziwei , Meng Xiangqi , Wang Xinyu , Song Dan , Xu Tianye , Tian Kaifu , Sun Penggang , Zhong Junzhe , Song Yu , Ma Wenbin , Liu Yuxiang , Yu Daohan , Shen Ruofei , Jiang Chuanlu , Cai Jinquan
Published: July 2023

Background Temozolomide (TMZ) resistance is one of the major reasons for the poor prognosis of glioblastoma patients. Long noncoding RNAs (lncRNAs) are widely involved in multiple biological processes, including TMZ resistance. We previously showed that Linc00942 is a potential regulator of TMZ sensitivity in glioblastoma (GBM) cells. However, the underlying mechanism of TMZ resistance induced by Linc00942 is unknown. Methods We performed a rapid amplification of cDNA ends (RACE) assay in TMZ-resistant GBM cells to confirm the sequence of Linc00942. ChIRP-MS and ChIRP-WB assays showed that Linc00492 interacted with TPI1 and PKM2. Molecular docking analysis, RNA pull-down, and RIP assays were used to demonstrate the underlying mechanisms of Linc00942 binding with TPI1 and PKM2. Native PAGE was used to identify the polymers of TPI1 and PKM2. The efficiency of Linc00942-mediated TMZ resistance was detected in vitro and in vivo. Results In this study, we identified the sequence of Linc00942, and further experiments confirmed that Linc00942 contributes to self-renewal and TMZ resistance in GBM cells. Linc00942 interacts with TPI1 and PKM2, subsequently promoting the phosphorylation, dimerization, and nuclear translocation of both proteins. The interaction of Linc00942 with TPI1 and PKM2 leads to increased acetylation of H3K4 and activation of the STAT3/P300 axis, resulting in the marked transcriptional activation of SOX9. Moreover, knockdown of SOX9 reversed the TMZ resistance induced by Linc00492 both in vitro and in vivo. Conclusions Linc00942 strongly promotes SOX9 by interacting with TPI1 and PKM2, thereby driving self-renewal and TMZ resistance in GBM cells. These findings provide potential combined therapeutic strategies to overcome TMZ resistance in GBM.
A queueing simulation method for evaluating the performance of resource management in mutual mode
Authors: Akuamoah Worlanyo Saviour , Ayimah John Coker , Mahama Francois , Bonsi Prosper Obed , Yaro David
Published: July 2023

We model a queueing resource management in mutual mode. When analyzing the performance of the service system, we often use the queueing theory to get the various performance indexes. As the number of resources in the service system with interactive mode increases due to users' sharing behavior, it becomes very difficult to get a steady state of the system. We investigate how to evaluate the performance of such a service system in which the amount of resources changes over time on accounts of users' sharing behavior. In the process of solving, an algorithm is designed to evaluate the convergence of performance indicators. The algorithm effectiveness is verified by the simulation test of the evaluation system and the simulation frequency range of convergence of service performance indicators. We compare the queueing process in the mutual mode to the non-mutual mode and then obtain a steady state for the mutual mode. The unique phenomenon in interactive mode, which is a performance inflection point, is found which has a guiding significance for efficient production.
Influence of Weight-Functions on the Performance of Element-Free Galerkin Method
Authors: Nagevadiya Bhumik , Bhoraniya Rameshkumar
Published: July 2023

The influence of the weight functions on the performance of the element-free Galerkin method has been studied. The convergence and computational cost using various functions for 1D and 2D structural models are examined. Acceptable ranges, as well as the best scaling parameters for each weight function, are pointed out. Mesh-free methods are completely independent of mesh and approximate the governing partial differential equations based on the only set of nodes. We have discussed the analysis of six different weight functions using the physical nature of field problems and show that the continuity of mesh-free shape function i.e., moving least square shape function depends on weight function. It is observed that the so-called weight function which is showing a minimum error is not always true. The convergence & computational cost (computation time) are also important factors. The manuscript contains the solution of 1D and 2D elastostatic problems with ten different weight functions. Paper represents the comparative study of different weight functions to predict the best field behavior with systematic analysis of each case.
Properties of High Volume GGBS based Concrete with Carbonation Curing
Authors: Debbarma Aravinda
Published: July 2023

Manufacturing of portland cement is an energy-intensive process and releases a large amount of greenhouse gases into the atmosphere, which affects the earth’s ecosystem. Efforts are being carried out to conserve energy by means of promoting the use of industrial wastes like Ground Granulated Blast Furnace Slag (GGBS), silica fumes, flyash, etc., which show chemical properties similar to cement. Replacement with industrial waste products like GGBS, flyash, silica fume, etc. which are having pozzolanic property same as cement will help to reduce the rate of cement consumption. This study evaluates the mechanical properties of concrete with Ground Granulated Blast-furnace Slag (GGBS). In the GGBS based concrete, cement was replaced with GGBS ranging from 60% to 80% and the specimens were cured with water/CO2 gas curing. Carbon Dioxide gas curing is an advanced curing process for cementitious material that provides strength at an early stage of the curing process, also known as an accelerated curing technique. Concrete when combined with Carbon Dioxide gas as a curing agent under specified temperature, pressure and duration gives an early strength at a short period of curing time. The curing of the concrete specimens was performed with water for 28 days/CO2 gas for 6 and 12 hours. The addition of CO2 as a curing agent for the concrete specimens also results in the production of more ettringite and C-S-H gel in the concrete. It also shows a huge amount of calcium hydroxide and the C-S-H hydration product under Scanning Electron Microscope (SEM) images. This study reveals that curing with CO2 gas gives better compressive and flexural strength at an early age for concrete mix with high volume GGBS than ordinary cement concrete.
Performance Evaluation of UHPFRC Plates subjected to Low-velocity Impact Loading
Authors: Mishra Suruchi , Sharma H. K.
Published: July 2023

In the present study, an attempt has been made to study the behavior of ultra-high performance fiber reinforced concrete (UHPFRC) plate specimens under impact loading analytically using the ANSYS V20.R2 explicit dynamics software. In this regard, UHPFRC plate specimens with sizes 500 × 500 × 50 mm were modeled and analyzed using a 5.25 kg impactor with a 500 mm drop height. The typical results of analytical investigations have been analyzed and discussed to study the behavior of UHPFRC plate specimens in light of the stress-strain behavior, deformation-time behavior, acceleration-time behavior, energy absorption capacity, failure characteristics, etc. The analytical results are compared with the experimental results for 4-side and 2-side simply supported (SS). It has been observed that experimental and analytical values are in good agreement regarding stress, strain, deformation, acceleration, energy absorption capacity, and failure characteristics. However, the variation in analytical and experimental values was because several pieces of equipment and accessories were used in the experimental investigation. Additionally, it has also been noticed that adding fibers reduces UHPFRC plates' deflection and acceleration while increasing the energy absorption capacity and stress and strain values for fiber content corresponding to 8%. However, increasing the deformation capacity of the plates by adding large quantities of fibers in the case of low-velocity impact is not very beneficial. The addition of MSF in UHPFC enhances the stiffness as well as strength of the composites. As the number of supported sides increased, the deflection and acceleration values decreased significantly.
Practical Approach to Strengthening of Pre-Engineered Building for Additional Futuristic Load using Mild Steel (MS) Section
Authors: Patil Pratik m. Patil Pratik m. , Patil Savita N. Patil Savita N. , Desai Piyush P. Desai Piyush P.
Published: July 2023

Technological advancements have greatly aided in improving the quality of life through a variety of new products and services. Pre-Engineered Building (PEB) is among such technological advancements in structural engineering. Pre-engineered buildings (PEB) are nothing but steel buildings in which excess steel is avoided by tapering the sections as per the bending moment’s requirement. Now the day’s PEB industrial sector is developing very fast, & its growth has increased widely after some years Electricity is very essential for the PEB industrial sector that’s why every PEB industry uses solar power energy through the installation of solar panels on or above the industry rooftop of existing PEB industrial structures. But at that time need to strengthen the existing PEB industrial structure while the industry is in working condition. This paper reviews the analysis and design of existing PEB industrial structures with and without added solar panels load (futuristic load) to them, which have been carried out using STAAD. Pro software & find out the member strengthening requirement base on the STADD Pro results like Bending moment & stress. Two different techniques are currently used to increase or restore the load-carrying capacity of PEB structures: 1) Bonding FRP sheets and 2) welding mild steel plates. Strengthening by mild steel plate is a popular method due to its availability, cheapness, uniform materials properties (isotropic), ease of work, high ductility, and high fatigue strength. This paper suggests various/ different Techniques or sections are used for strengthening existing PEB industrial structures using mild steel sections/ plate (MS). These techniques are Practically possible, economical, optimum, & suitable for the strengthening of existing PEB structures. which are very important to improve the load-carrying capacity of steel structures while adding solar panels load to them. This paper uses Mild steel (MS) Plate welding in different locations/patterns as per the strengthening requirement and will be carried out using STADD Pro & ANSYS Software.
Nonlinear relationships between built environmental characteristics and ridership in Xi'an metrostation
Authors: Xi Yafei , Hou Quanhua , Duan Yaqiong , Lei Kexin , Wu Yan , Cheng Qianyu
Published: July 2023

In recent years, Xi'an metro construction has been progressing rapidly, becoming the primary mode of urban green public transportation. Since the ridership of the metro is closely linked to the characteristics of its surrounding built environment, a key problem in promoting the benign development between the two is to explore the spatiotemporal distributional difference in ridership and its influencing factors. In this study, the "5D" characteristics of built environment are described by density, diversity, design, destination and distance variables. The spatiotemporal distribution characteristics of ridership are analyzed via Arc GIS and Python, while the nonlinear relationships between ridership and built environment of 106 metro stations of downtown Xi'an, as well as relevant threshold effects are revealed via Shapley additive explanations  with gradient boosted decision tree (GBDT-SHAP). The results show that: (1) Xi'an metro travel presents a medium-short spatiotemporal distribution, and the ridership network is characterized by strong center-spillover. (2) The nonlinear relationship between built environment and ridership is ubiquitous and presents a threshold effect. The impact threshold of bus stop density on ridership is 4-6 pcs/km2, the impact threshold of road network density is roughly 4-5 km/km2, and the effective threshold of building density does not exceed 20%. (3) The positive impact of POI facility density on peak ridership is stronger than that at flat hours. Variables like land use mixture, population density and distance from downtown have a time-driven effect on the ridership, whose importance and influence change with time. This study provides a better understanding of the spatiotemporal impact of Xi'an's built environment on metro travel, which is of profound significance for the coordinated development between the city and metro construction.
Temporal and spatial dynamics of pesticide use in three field vegetable crops with respect to sowing date and degree days
Authors: Räsänen Kati , Kaseva Janne , Aaltonen Marja , Vänninen Irene
Published: July 2023

We analyzed the timing of pesticide treatments for eventual analysis of temporal environmental risks associated with pesticide use in field vegetable crops. We also investigated the extent to which timing of treatments reflected predicted flight times of pests to gain an understanding of whether farmers followed the model predictions in their decision-making as part of Integrated Pest Management (IPM). The data cover chemical plant protection in field vegetable farms in southwestern Finland in 2009–2019.
The timing of treatments, made with different pesticides in the weeks following sowing, corresponded with the known phenology of different pests of the three crops. The same was true for the carrot fly, the pea moth and the 2nd generation of the cabbage root fly when phenological models using historical data were used to predict the timing of treatments. Carrot psyllids, root flies and pea moths were the most targeted insects in carrot, swede and peas, respectively. Spray frequencies against carrot psyllid increased over time for carrot. The use of insecticides was least for fresh pea.
We conclude that farmers acted in accordance with the principles of IPM when practising chemical control. For those species that lacked phenological predictive models in the study years, the degree days for the observed timing of treatments can be used as a starting point if such models are developed in the future. Our results can be used as a long-term baseline in future surveys on the changes in pesticide use and their risks regarding the studied crops.
Exploring the Place Dynamics of Roadside Space Conflicts with Street View Images: The Case of Beijing
Authors: Dang Anrong , Li Xiangyu , Chen Maini
Published: July 2023

Conflicts between vehicles, cyclists, and pedestrians have been increasingly investigated as automobiles marginalize other types of mobility in crowded public spaces, particularly in roadside spaces where active mobility meets automobiles. These conflicts are extremely visible in Beijing, one of the world's most congested cities. This study explores the fined-grained spatial patterns of roadside space conflicts and factors associated with two types of conflicts (vehicle-bike, and vehicle-pedestrian). A systematic method combining spatial sampling and machine learning is described to capture the frequency of conflicts between vehicles, cyclists, and pedestrians from street view images. The ridge regression analysis identifies places with a higher probability of generating roadside space conflicts and disparate dynamics between urban and suburban/rural communities. The results of the analysis are compared with the current street regeneration plan in Beijing, which suggests that future plans should incorporate place-based roadside space management strategies in addition to the provision of on-street parking facilities.
Tobacco consumption behavior change during the COVID-19 pandemic is associated with perceived COVID threat
Authors: Loui Hollyann F. , Li BS Joshua , Jackson PhD Nicholas J. , Wisk Lauren E. , Buhr
Published: July 2023

Rationale:
Tobacco use is a risk factor for COVID-19 adverse outcomes. Despite health implications, data conflict regarding COVID-19 and tobacco consumption. We present results from a survey of health behaviors during the pandemic to identify how COVID-19 influenced tobacco use.
Methods:
A national internet-based survey was deployed between May-September 2020. We analyzed participants who reported current or former smoking. We tabulated change in tobacco use, whether changes related to COVID-19, and measures of anxiety, depression, and novel perceived COVID-19 threat scale. We employed multinomial logistic regression to determine associations between these items and tobacco consumption.
Results:
We identified 500 respondents who reported ever smoking previously, 150 of which were currently smoking. Of 220 participants who reported any use of vapes, 110 were currently vaping. Increased perceived threat of COVID-19 was associated with both increased (aRRincrease 1.75, 95% CI [1.07–2.86], P = 0.03) and decreased (aRRdecrease 1.72 [1.04–2.85], P = 0.03) tobacco consumption relative to no change. There were no significant relationships found between perceived threat of COVID-19 and vaping behavior.
Conclusions:
As perceived COVID-19 threat increased, people were more likely to increase or decrease their smoking than stay the same, even after controlling for anxiety and depression, both of which can affect smoking in either direction. Further study into motivators of increasing or decreasing affected tobacco consumption, and how barriers to care from safer-at-home policies and changes in care delivery moderate change in tobacco use will aid planning tobacco reduction interventions during the ongoing and future respiratory viral pandemics.
GTAP-E: A Revised Energy-Environmental Version of the GTAP Model
Authors: McDougall Robert , Golub Alla
Published: July 2023

The purpose of this memorandum is to document recent revisions to the energy environmental extension of the GTAP Model (GTAP-E) described in GTAP Technical Paper No.16 by Burniaux and Truong (2002). We revise the solution program, data, stored input and command files, and welfare decomposition program. The revisions are undertaken to improve the model's user friendliness, adapt it to a wider range of energy-environmental policy scenarios, and correct errors. A technical paper documenting the theoretical structure of GTAP-E is forthcoming.
Projections for World CGE Model Baselines
Authors: Chappuis Thomas , Walmsley Terrie
Published: July 2023

While constructing a new baseline for the GDyn model, we spent a lot of time collecting projections and deciding which data to choose. We also developed programs to aggregate projections to any specific geographical aggregation of the GTAP Data Base. In order to help researchers in the construction of their own baselines, we created a baseline section1 on the GTAP website where GTAP users can find the projections data and programs. The purpose of this paper is to document the data used in our new GDyn baseline and to provide a user guide of the baseline website. Our view is that sharing data and expertise with researchers working on baselines will help create reliable and defendable baseline scenarios. The second annex documents the aggregation programs from the 112 GTAP 7.1 regions to a specific geographical aggregation.
Dynamic Effects of the "New Age" Free Trade Agreement between Japan and Singapore
Authors: Hertel Thomas , Walmsley Terrie , Itakura Ken
Published: July 2023

As manufacturing tariffs have fallen worldwide, the focus of free trade agreements has shifted towards other issues, including: rules governing foreign investment, e-commerce regulations, trade in services, harmonization of technical standards, sanitary and phyto-sanitary regulations, and the streamlining of customs procedures. Japan and Singapore are undertaking negotiations over this kind of "new-age" FTA. The purpose of this paper is to evaluate the impact of the FTA on production, consumption, trade, international investment flows, GDP and welfare. We use a modified version of the dynamic GTAP model, which is well-suited to capturing the impact of this new-age FTA over both the short run and the longer run.
International Cross Section Estimates of Demand for Use in the GTAP Model
Authors: Reimer Jeff , Hertel Thomas
Published: July 2023

The making of projections often requires an economy-wide perspective, and the estimation of consumer demands at the international level. In this paper, an implicit, directly additive demand system (AIDADS) is estimated using cross-country data on consumer expenditures from the International Comparison Program (ICP), and then from Global Trade Analysis Project (GTAP) data. The two data sets are found to produce results that are quite consistent despite their differing origins, and the fact that the former is based on consumer goods that embody wholesale/retail margins, while margin demands are treated separately in GTAP. Given the similarity of the results, the estimation based on GTAP data is favored because it is readily matched to input-output based production and trade data, and provides valuable new information concerning how aggregate margin expenditures are related to per capita income.
Bilateral Free Trade Agreements and Customs Unions: The Impact of the EU Republic of South Africa Free Trade Agreement on Botswana
Authors: Walmsley Terrie , McDonald Scott
Published: July 2023

The EU has indicated that after 2008 its trade relationships with developing countries will be dominated by the development of preferential trade agreements. Although not a consequence of the Cotonou Agreement, the free trade agreement between the EU and the Republic of South Africa (EU RSA FTA) is clearly one of the first fruits of this approach to trade relationships. However, there is no evidence that the design of the EU RSA FTA incorporated a comprehensive general equilibrium evaluation of the agreement for either the signatories or the other southern African nations. The analyses reported here indicate that while the EU RSA FTA may substantially benefit the signatories, there are appreciable negative impacts for other states, especially the RSA’s immediate neighbours. Moreover, the reluctance of the EU to fully liberalise trade in food and agriculture commodities results in a major reduction in the benefits for the RSA without ameliorating substantively the adverse implications for other nations.
CRÍTICA DE GAVIN D’COSTA A LA TEOLOGÍA PLURALISTA DE LAS RELIGIONES DE JOHN HICK
Authors: Santamaría del Río Luis
Published: July 2023

En este artículo se presenta el pensamiento teológico de Gavin D’Costa sobre las religiones no cristianas, partiendo de la crítica que hace en su tesis doctoral al paradigma pluralista de John Hick. D’Costa rebate, punto por punto, la llamada “revolución copernicana” que el teólogo pluralista inglés plantea en sus obras y, de este modo, elabora una profunda crítica de la teología pluralista de las religiones. La obra de Gavin D’Costa se constituye así en uno de los intentos mejor fundamentados para establecer, dentro de la tradición católica, un inclusivismo cristocéntrico, que conjugue la universalidad salvífica de Dios con la unicidad de Cristo, sin olvidar el importante papel de la Iglesia en la economía de la salvación.
RETOS DE LA SOCIEDAD CONTEMPORÁNEA A LA UNIVERSIDAD CATÓLICA
Authors: Sánchez Caro José Manuel
Published: July 2023

Las universidades católicas en la formulación de sus proyectos educativos requieren conjugar, tanto la identidad cristiana católica como la apertura a la sociedad en la que viven y con cuya cultura dialogan. Desde este punto de partida, el presente ensayo propone cinco desafíos desde los cuales las Diversidades Católicas sirven a la sociedad: Ofrecer un saber de calidad; Instar a la búsqueda de la verdad; Procurar el diálogo entre la fe y la razón, la fe y la ciencia; Educar ciudadanos y cristianos críticos; finalmente, ser un instrumento de evangelización en el ámbito universitario.
A AÇÃO DE DEUS NO MUNDO SEGUNDO KARL RAHNER
Authors: Miranda Mario de França
Published: July 2023

O presente artigo trata de uma questão fundamental para o cristianismo. Pois, sendo Deus transcendente ao nosso mundo, como Ele pode atuar neste mundo? Já no universo filosófico o problema se coloca na complexa relação entre transcendência e história. Somos uma religião que confessa um Deus que se encarnou, que como cria-dor de toda a realidade governa este nosso mundo, que age em homens e mulheres para que sejam seus colaboradores na propagação de seu desígnio salvífico. Se não duvidamos deste fato, encontramos muita dificuldade para explicálo. Apresentamos, em grande fidelidade ao autor, o pensamento de K. Rahner sobre esta questão. Termi-namos com uma breve apreciação.
BACH DIALOGA CON MOZART. LA TEOLOGÍA ESTÉTICA DE JOSEPH RATZINGER
Authors: Blanco Sarto Pablo
Published: July 2023

Ratzinger considera la belleza como una dimensión constitutiva de la realidad. Es además una necesidad para el cristianismo, también con vistas a la evangelización. El teólogo alemán aborda así la música sacra y litúrgica, la arquitectura y la iconografía cristianas, así como también el arte profano. Esta belleza artística puede estar unida al bien, aunque a la vez puede existir también una belleza luciferina. Además, en el arte, la razón ha de presentarse unida a los sentidos y los sentimientos. Para el cristiano, la belleza definitiva será la belleza de Cristo, que comprende amor y dolor. Es la Belleza crucificada y resucitada y, por lo tanto, eterna.
APROXIMACIÓN HISTÓRICA, CULTURAL Y TEOLÓGICA A LA VIRGEN APOCALÍPTICA DE QUITO
Authors: Riofrío Martínez-Villalba Juan Carlos , Jaramillo Arango Diego
Published: July 2023

El presente es un estudio teológico de la figura más emblemática de la cultura quiteña: la Virgen alada tallada en el siglo XVIII por Bernardo de Legarda. Como ordinariamente se la identifica con la Virgen del Apocalipsis 12, primero se analiza el texto bíblico a la luz de las nuevas y tradicionales interpretaciones que se le han dado. A con-tinuación se revisan los rasgos principales de la Mujer apocalíptica, para, con estos antecedentes, confrontarlos con los datos proporcionados por la imaginería quiteña a la Virgen alada. En concreto, se analiza el significado de la vestimenta de Sol, la Luna bajo sus pies, la corona de estrellas, el hecho de que está en cinta y que sufre dolores de parto, y sus alas de águila grande. La conclusión es que esta imagen es esencialmente la Virgen apocalíptica, pero enriquecida teológica e iconográficamente con los signos de la mujer del Génesis y con los de la cultura quiteña.
UN EVANGELIO TRASPASADO POR LA ORACIÓN. TEXTOS SELECTOS DE LUCAS
Authors: Cardona Ramírez Hernán , Santís Pinedo José Antonio
Published: July 2023

En el evangelio de Lucas una de las dimensiones centrales de la vida de Jesús de Nazaret es aquella de su oración. Al seleccionar algunos pasajes sobre la oración, el artículo muestra cómo la oración del Maestro está vinculada de manera muy estrecha con su vida y con la misión confiada por el Padre (Abba). Para la obra lucana, Jesús es un hombre de oración, en ella expresa la riqueza de su vida interior, su misión perso-nal, y también aquella de los discípulos. Entre los variados textos sobre “Jesús orante en san Lucas”, la exposición se detiene en un pasaje donde Jesús asoma con mayor propiedad como maestro de oración: se trata de la versión lucana del Padre nuestro; además descubre cómo la oración está presente en los relatos del nacimiento, durante la misión en Galilea y en la Pascua final en Jerusalén.
CAMINO: LITERATURA Y ESPIRITUALIDAD
Authors: Ánchel Constantino
Published: July 2023

En septiembre de 1939 se publicó, en Valencia, Camino, el libro más conocido de San Josemaría Escrivá de Balaguer. Este artículo reproduce, con ligeras variantes, una conferencia pronunciada en una Residencia Universitaria de Valencia2, en la con-memoración del 75 aniversario de su publicación. Las líneas que siguen pretenden aportar algunas consideraciones sobre las características literarias de Camino y su implicación en la transmisión del mensaje espiritual del libro. Aunque no es incorrec-to encuadrar a Camino dentro del género aforístico, sin embargo, el libro no es fruto de una elección previa de un género literario: no obedece a un proyecto inicial preciso de escribir una obra y, menos, una obra de un género literario concreto. Camino nació de las necesidades que al autor le planteaba su labor apostólica. Y en ese contexto, se percibe que el estilo literario se subordina a la transmisión de un mensaje. Por otra parte, no hay que perder de vista que Camino no es un tratado teológico. Ciertamente contiene abundantes elementos para esbozar algunos trazos de esa espiritualidad, pero son insuficientes. Con todo, el contenido de Camino rezuma el mensaje que san Josemaría transmitió desde el 2 de octubre de 1928.
M. BESIO, R; A. SERANI M., Sabiduría, Naturaleza y Enfermedad, Una com-prensión filosófica de las profesiones de la salud. Ediciones UC, Santiago, 2014. 181 pp. ISBN 978-956-14-1437-2.
Authors: Sánchez Echeverría Lorena
Published: July 2023

Alejandro Serani Merlo es médico neurólogo por la Universidad de Chile, Doctor en Filosofía por la Universidad de Toulouse Le Mirail, Toulouse, Francia; Director del Centro de Bioética en la Facultad de Medicina de la Pontificia Universidad Católica de Chile y, miembro ordinario de la Aca-demia Pontificia para la Vida (Ciudad del Vaticano). Por su parte el doctor Mauricio Besio Rollero es médico-cirujano de la Universidad de Chile, con especialización en obstetricia y ginecología en la Pontificia U. Católica de Chile y es Magíster en Fundamentación Filosófica de la U. de los Andes. Actualmente se desenvuelve como profesor asociado de la Pontificia Uni-versidad Católica de Chile, en las áreas de sexualidad, ginecología quirúr-gica y bioética.
THE INFUSED SCIENCE OF CHRIST, ACCORDING TO THOMAS AQUINAS
Authors: White Thomas Joseph
Published: July 2023

This paper establishes a contrast between the Thomistic conception of Christ’s de-grees of knowledge with the contemporary conception of the same. It proves the fruit-fulness of Aquinas’ division of Christ’s knowledge in four kinds (one divine, three human: vision of God, infused science, and acquired knowledge) in order to deal with the problem of harmonizing Christ’s modes of human knowledge. Very particularly, it holds that Jesus articulated in his human language and with his acquired knowledge (culturally situated) that part of his potentially infinite human knowledge when it was relevant for his salvific mission.
CONCIENCIA Y LIBERTAD COMO EXPRESIONES DE LA SUBJETIVIDAD Y CONSTITUTIVO FUNDAMENTAL DE LA EXISTENCIA HUMANA, EN EL PENSAMIENTO TEOLÓGICO DE JUAN ALFARO
Authors: Ábrigo Otey Carlos
Published: July 2023

El giro antropológico establecido por el Vaticano II significó para el teólogo jesuita español Juan Alfaro −entre otras cosas− la posibilidad de desarrollar una teología esencialmente vinculada a una reflexión antropológica sólida. Para tal efecto, enten-dió que las categorías enmarcadas en el esencialismo cósico debían dar paso a las de persona, subjetividad e historia, valiéndose para ello del método fenomenológico trascendental. Ello comportaba, en consecuencia, dedicarse asiduamente al análisis existencial de las infraestructuras antropológicas implicadas en la existencia cristiana a objeto de penetrar en la comprensión de uno de sus grandes desafíos teológicos: la apertura del espíritu finito al horizonte ilimitado del ser. Dentro de tales estructuras antropológicas se hallan −ciertamente− la conciencia y la libertad, entendidas como las dimensiones que configuran de la subjetividad humana. Este artículo −precisamente− pretende esbozar una pequeña muestra de este em-peño teológico de Alfaro, donde la subjetividad se erige como el ámbito de convergen-cia entre Dios y el hombre, que genera una tensión existencial en él, y que lo orienta hacia su autotrascendencia.
ANKOMMEN OHNE ENDE“. DOGMATISCH-THEOLOGISCHE ÜBERLEGUNGEN ZU TOD UND AUFERSTEHUNG
Authors: Eckholt Margit
Published: July 2023

Der Beitrag geht aus dogmatisch-theologischer Perspektive auf Grundfragen der Eschatologie in der deutschsprachigen Theologie der Gegenwart ein. Diskutiert wird die bis in die Gegenwart hineinreichende theologische Debatte um die „Auferstehung im Tod“, eine These, die seit den 70er Jahren von Gisbert Greshake und Gerhard Lohfink vorgelegt wird und die von Joseph Ratzinger in seiner „Eschatologie“ zurück-gewiesen worden ist. Der Beitrag versucht, die These der „Auferstehung im Tod“ auf dem Hintergrund eines prozesshaften Verständnisses eschatologischer Existenz und eines Lebens „nach“ dem Tod zu vertiefen. Systematisch-theologische Leitperspektive des Beitrags ist ein „intellectus spei“, der davon ausgeht, dass jede Denk- und Sprach-form, die sich dem Glaubenssatz von der „Auferstehung der Toten“ annähert, in das „Wunder“ bleibende Geheimnis der Auferstehung eingeschrieben sein muss.
VEINTE AÑOS DE TEOLOGÍA DESDE CONCEPCIÓN-CHILE: REVISTA ANALES DE TEOLOGÍA 1998-2018
Authors: Uribe Ulloa Pablo
Published: July 2023

Veinte años de investigación teológica quedan plasmados en los trabajos publicados por la revista Anales de Teología del Instituto de Teología de la Universidad Católi-ca de la Ssma. Concepción de Chile. Se presenta aquí un índice completo de todo lo publicado por An.teol. dividido en distintos apartados con el fin de facilitar la lectura y búsqueda bibliográfica de los investigadores e interesados en temáticas teológica, religiosa, bioética y de estudios de la religión.
UNA IGLESIA HÍBRIDA: POLIFONÍA Y MIXTURA EN LA COMUNIDAD DE JESÚS
Authors: Achondo Moya Pedro Pablo
Published: July 2023

En el siguiente trabajo se busca reflexionar en torno a otras figuras eclesiológicas. Ins-pirados en el camino y experiencia de la Iglesia en América Latina, en lo que respecta a la Teología de la Liberación y su praxis sociopolítica; y a partir de las reflexiones de los estudios ecológicos de las últimas décadas, presentamos algunas intuiciones para una “otra forma eclesial” desde donde son problematizadas las relaciones de poder, la autoridad y las maneras tradicionales de comprender la pastoral en la Iglesia. Tarea en la cual el papa Francisco ha insistido. Para ello acuñamos la idea de lo híbrido para esa posible otra eclesiología. Tanto el contexto presente de crisis institucional de la Iglesia (y su teología) como la situación de amenaza civilizatoria nos invita a buscar otras formas de pensar, nue-vas aproximaciones en lo que respecta a las relaciones humanas, sus comunidades y organizaciones. De ahí que este estudio sea pertinente. Muchas veces se ha criticado que la Iglesia llega tarde a ciertas temáticas y reflexiones que desde las ciencias so-ciales y el mundo científico-técnico van más avanzadas. El evangelio, desde su dinámica encarnatoria, exige al cristiano de hoy indagar y dialogar con las líneas fundamentales del pensamiento actual.