bluuebunny/crossref_metadata_2025 huggingface dataset:
Late presentation of Noonan syndrome as atrial flutter in an adult
Authors: Al-Jobory Ola , Dweik Anass , Muhammed Anees , Rasheed Waqas , Mohammed Ibrahim , McMaster Kelly , Gulati Rajeev
Published: July 2023

Noonan syndrome is a rare genetic disease with multisystemic manifestations, typically diagnosed in infancy and childhood. This case report presents a 53-year-old woman with no significant medical history who presented with shortness of breath and was subsequently diagnosed with Noonan syndrome. The patient exhibited characteristic facial dysmorphology, including a narrow face, low set ears, and pectus excavatum. Physical examination revealed a crescendo-decrescendo ejection murmur and bilateral lower limb edema. Atrial flutter with rapid ventricular response was detected, and further investigations revealed a large secundum atrial septal defect (ASD) and other cardiac abnormalities consistent with Noonan syndrome. The patient was transferred to a tertiary center for evaluation and management by adult congenital disease specialists. This case highlights the atypical presentation of Noonan syndrome in adulthood and emphasizes the importance of recognizing this condition in patients with cardiac anomalies, as it can impact perioperative management and necessitates genetic counseling.
Keywords: Noonan syndrome, genetic disease, multisystemic manifestations, atrial septal defect, adult presentation
The Basic Core of a Parallel Machines Scheduling Game
Authors: Alon Tzvi , Anily Shoshana
Published: July 2023

Problem definition: We consider the parallel machine scheduling (PMS) under job-splitting game defined by a set of manufacturers where each holds uniform parallel machines and each is committed to produce some jobs submitted to her by her clients while bearing the cost of the sum of completion times of her jobs on her machines. An efficient algorithm for this scheduling problem is well known. We consider the corresponding cooperative game, where the manufacturers are players that want to join forces. We show that collaboration is profitable. Yet, the stability of the cooperation depends on the cost allocation scheme; we focus on the core of the game. Methodology/results: We prove that the PMS game is totally balanced and its core is infinitely large, by developing a sophisticated methodology of linear complexity that finds a line segment in its symmetric core. We call this segment the basic core of the game. Managerial implications: This PMS game has the potential for various applications both in traditional industry and in distributed computing systems in the hi-tech industry. The formation of a partnership among entrepreneurs, companies, or manufacturers necessitates not only a plan for joining forces toward the achievement of the ultimate goals, but also an acceptable agreement regarding the cost allocation among the partners. Core allocations guarantee the stability of the partnership as no subset of players can gain by defecting from the grand coalition.

Funding: This work was supported by the Henry Crown Israeli Institute for Business Research, the Coller Foundation, and the Israel Science Foundation [Grant 1489/19].
Incarcerated individuals and education programmes in Nigeria: A task for social workers
Authors: Uche Ijeoma B. , Uche Okala A. , Okoye Uzoma O. , Ukoha-Kalu Blessing Onyinye
Published: July 2023

Much is not known about education programmes for Nigerian incarcerated individuals. Consequently, different correctional institutions worldwide have different forms of correctional education offered to incarcerated individuals. Nigerian incarcerated individuals perceive that there are implementations of education programmes offered to them. However, little or nothing is known about how incarcerated individuals perceive these education programmes. To this end, this study ascertains the incarcerated individuals’ perception of education programmes as well as the expectations of social work profession in ensuring that incarcerated individuals in correctional institutions are provided with quality education. In-depth interviews involving 20 convicted incarcerated individuals from Owerri correctional centre were conducted. Thematic analysis was used in analyzing data generated for the study. Findings show that education programmes are available and essential, but the quality of the programme does not go down well with the incarcerated individuals. It also revealed that incarcerated individuals were not allowed to decide on the type of education programme to be involved in. To this end, their participation in the programme is jeopardized. The findings further revealed that little or nothing is known about social workers in prison education. Therefore, the inclusion of correctional social workers as an integral part of education programmes that aim to reform, rehabilitate and reintegrate incarcerated individuals becomes necessary.
Kell még szurkoló a stadionokba? : A csapattal való szurkolói azonosulás és a csapathoz való kötődés vizsgálata egy hazai futballklub esetébe
Authors: Bodon György , Kajos Attila , Neulinger Ágnes
Published: July 2023

A szurkolók csapathoz való kötődésének kialakítása, új szurkolók bevonzása egy fejlett sportgazdaságban elengedhetetlen. Magyarországon ez a téma évtizedes megoldatlan problémát jelent, miközben látványos beruházásokkal új stadionok épültek, melyek kihasználtsága a hazai labdarúgó bajnoki mérkőzések esetében jelentős mértékben fejleszthető lenne. A szerzők tanulmányukban az OTP Bank Liga magyar elsőosztályú labdarúgó-bajnokságban szereplő Mol Fehérvár FC tekintetében vizsgálják a klub szurkolói közegét. Jelen kutatás célja a csapathoz kötődő lojalitással, szurkolói magatartással összefüggésben a csapattal való szurkolói azonosulás és a csapathoz való kötődés kapcsolatának elemzése. A kutatási kérdés annak megismerésére irányul, hogy a csapattal való szurkolói azonosulás, a csapathoz való kötődés miként befolyásolja a csapathoz fűződő lojalitást, szurkolói magatartást. A kutatás legfőbb eredménye az a felismerés, hogy a vizsgált csapat szurkolói esetében a kiábrándultság, a csapathoz kötődés érzésének erodálódása olyan probléma, amit a klubnak kezelnie kellene, hogy nézőszáma és ebből következően bevétele növekedjen.
Regionalbeihilfen und Kohäsion
Authors: Marques Alfredo
Published: July 2023

Die Finanzhilfen an Unternehmen, insbesondere für deren produktionswirksame Investitionen, sind eines der wichtigsten Instrumente der von der Europäischen Gemeinschaft in den Jahren 1989–1993 durchgeführten Politik des wirtschaftlichen und sozialen Zusammenhalts (Kohäsion). Sie ist, kurzgefaßt, ausgerichtet auf den Ausgleich der strukturellen Wettbewerbsnachteile der am wenigsten entwickelten Regionen der Union. Hierzu sind diese Regionen in den Genuß erheblicher finanzieller Transfers aus den Strukturfonds gekommen.Der vorliegende Beitrag versucht indessen darzulegen, daß trotz der bedeutenden Auswirkungen dieser innergemeinschaftlichen Solidarität die Möglichkeiten der unterentwickelten Regionen im Bereich der Hilfen für Unternehmen im allgemeinen hinter denen der prosperierenden Regionen Zurückbleiben. Der Verfasser schlägt für die nächste Programmperiode der Strukturfonds, beginnend 1994, drei Arten von Maßnahmen zur Vermeidung dieser Situation vor.
Tat-Orte und Angst-Räume
Authors: Kramer Caroline , Mischau Anina
Published: July 2023

Das Thema Gewalt gegen Frauen im öffentlichen Raum und die Bedrohung von Frauen durch diese Gewalt ist ein Problembereich, der nicht nur im gesamtgesellschaftlichen Kontext, sondern in der jüngsten Zeit zunehmend auch auf kommunaler Ebene diskutiert wird. Dies geschieht nicht zuletzt aus dem Grund, daß sich konkrete Verbesserungen auf dieser Ebene leichter verwirklichen lassen und verstärkt auch von den betroffenen Frauen gefordert werden. Innerhalb dieses Diskussionsstranges ist auch unsere Studie anzusiedeln. Dennoch stellt sie in mancher Hinsicht einen neuen Ansatz dar, vor allem, was die Kombination von Ansätzen aus Soziologie und Sozialgeographie sowie die inhaltlichen Schwerpunkte anbelangt. Während sich der soziologische Blickwinkel der Opferwerdung von Frauen durch Gewaltdelikte sowie die empfundene Bedrohung auf der Handlungsebene widmet, werden im geographischen Teil die angst-räumlichen Bezüge zwischen den genannten Orten, den Wohnorten und den häufig frequentierten Stellen Heidelbergs hergestellt sowie mit den aus Polizeistatistik, Lokalpresse und Frauennotruf bekannten Vorfällen in Bezug gesetzt.
Effects of cancer mortality on life expectancy in European high-income countries between 1950 and 2019
Authors: Stirba Vitalie
Published: July 2023

This article aims to analyze the effects of cancer mortality on life expectancy at birth in 15 European high-income countries between 1950 and 2019. To establish the 1950–2019 time series of deaths from cancer, mortality data were harmonized from the available datasets of the World Health Organization Mortality database, coded according to the International Classification of Diseases of the 7th, 8th, 9th, and 10th editions. The estimation of the cancer mortality effect on the life expectancy at birth was performed using the algorithm of stepwise replacement for the life expectancy decomposition. The increase in cancer mortality contributed to a decline in overall life expectancy growth until the mid-1990s, coinciding with the aging cohorts of heavy smokers and a long-term reduction in mortality from other non-communicable diseases. Subsequently, since the 1990s, the reduction in cancer mortality has contributed to a significant increase in life expectancy at birth, especially in males. Reduction in cancer mortality was the outcome of various factors, such as alcohol and tobacco control policies, advances in cancer prevention and its treatment, general increase in population well-being, and reduction in risk-factors.
Business model transformation during the COVID-19 pandemic - example of the automotive industry
Authors:   University of Gdańsk, Poland, Dobrowolska Emilia , Sliż Piotr ,   University of Gdańsk, Poland
Published: July 2023

This article explores the impact of the COVID-19 epidemic on the business models of automotive-sector organizations, specifically authorized passenger car dealerships in Poland. The research aims to determine how business models were transformed during the pandemic. The research methods used include a literature review and opinion polls. The article begins by discussing the significance and evolution of business models and changes in the automotive sector. The results focus on how the pandemic brought about change in business models in the automotive sector, and the conclusion includes information as to limitations and further areas of study.
Bohaterka historyczna? – obrazy bohaterstwa na łamach „Kobiety i Życia” w latach 1989–1992
Authors:   Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Szwed-Walczak Anna
Published: July 2023

Słownik języka polskiego bohatera definiuje jako osobę „odznaczającą się niezwykłymi czynami”, „męstwem”, co czyni ją wyjątkową, ale też podziwianą i wartą pamięci potomnych. Informacje o bohaterach i ich osiągnięciach są więc upowszechniane oraz przekazywane z pokolenia na pokolenie. Treści na ten temat obecne były także na łamach polskiej prasy dla kobiet. Ukazywano wątki związane z historią oraz postaciami, które zapisały się na jej kartach w różnych dziedzinach życia publicznego, m.in.: w polityce, nauce, sztuce, literaturze, sporcie. Celem badań była rekonstrukcja obrazu bohaterki historycznej w polskiej prasie dla kobiet w latach 1989-1992. Aby zrealizować cel badawczy, sformułowano następujące pytania badawcze: 1) jaki jest udział pisarstwa o bohaterach, a jaki o bohaterkach na łamach polskiej prasy dla kobiet w latach 1989-1992?; 2) czym różnił się obraz bohatera od obrazu bohaterki?; 3) w jakiej dziedzinie życia dominowały „bohaterki”? Przedmiotem badań były artykuły opublikowane w „Kobiecie i Życiu”.
Katarzyna Jaczynowska (1872–1920) – życie i działalność muzyczna wielkiej pianistki
Authors:   Uniwersytet Jana Kochanowskiego w Kielcach, Pobocha Emilia
Published: July 2023

Katarzyna Jaczynowska (1872–1920), wybitna polska pianistka i pedagog, wychowywała się i kształciła w okresie, kiedy Polska była pod zaborami, kiedy każdy, nawet najmniejszy polski przejaw patriotyzmu na jakimkolwiek polu aktywności był wnikliwie obserwowany i tłumiony. Działalności artystycznej i pedagogicznej poświęciła z ogromną pasją niemal całe swoje życie. Odeszła na zawsze jeszcze w pełni sił twórczych, bo zaledwie w wieku 48 lat. Profesor Jaczynowska przeżyła tylko dwa lata w okresie międzywojennym, ale zostawiła solidnie przygotowany „grunt” pod rozwój nauki gry na instrumencie i kształtowanie pianistów wirtuozów w niepodległej Polsce.
Pomocnicza Służba Kobiet w Polskich Siłach Zbrojnych na Zachodzie (1940–1946). Aktualny stan badań i charakterystyka archiwaliów
Authors:   Instytut Pamięci Narodowej w Warszawie, Marcinkiewicz-Kaczmarczyk Anna
Published: July 2023

Historia Pomocniczej Służby Kobiet w Polskich Siłach Zbrojnych na Zachodzie nie została dotychczas gruntownie zbadana i opisana. Nie powstała jeszcze żadna monografia na ten temat. Najbardziej znanymi opracowaniami są Pomocnicza Wojskowa Służba Kobiet 2 KP (1941–1945) Anny Bobińskiej oraz Pomocnicza Służba Kobiet w Polskich Siłach Zbrojnych w okresie II wojny światowej Wandy Maćkowskiej. Obydwa zostały napisane przez świadków tamtych wydarzeń (Anna Bobińska należała do PSK), a więc nie są obiektywne i ograniczają się jedynie do ogólnego opisu dziejów formacji, a w zasadzie przedstawienia najważniejszych dokumentów – głównie rozkazów organizacyjnych i sprawozdań. W 1941 r. zaczęto przyjmować kobiety do Armii Andersa i wydawać rozkazy i zarządzenia regulujące zasady ich służby. Jednocześnie od 1942 r. powstawały pododdziały kobiece w Wielkiej Brytanii, gdzie w listopadzie tego roku utworzono Komendę Główną PSK w Londynie. Ostateczny rozkaz organizacyjny regulujący zasady służby kobiet w PSZ na Zachodzie został wydany w lipcu 1944 r.
Kobiety w Rozgłośni Polskiej Radia Wolna Europa. Analiza stanu badań na przykładzie Aleksandry Stypułkowskiej
Authors:   Uniwersytet w Białymstoku, Andrzejewska Ewelina
Published: July 2023

Historia kobiet pracujących dla Rozgłośni Polskiej Radia Wolna Europa nie jest w pełni opisana, temat nie został pogłębiony w takim samym stopniu, jak w przypadku mężczyzn zatrudnionych bądź współpracujących z RWE. Nie oznacza to jednak, że kobiety nie miały na swoim koncie rozmaitych osiągnięć jako dziennikarki, publicystki, reportażystki czy autorki teatru radiowego; prowadziły programy, przygotowywały audycje, pogadanki, felietony, komentarze, reportaże, słuchowiska; wielokrotnie uczestniczyły również w dyskusjach okrągłego stołu prowadzonych w studiu. Do tego grona należała m.in. Aleksandra Stypułkowska (pseudonim radiowy Jadwiga Mieczkowska), jedna z najwybitniejszych komentatorek politycznych i społecznych Rozgłośni Polskiej Radia Wolna Europa. Wagę jej dziennikarskiej pracy potwierdzają liczne materiały archiwalne oraz źródła literackie. Mimo pokaźnego dorobku publicystycznego i wieloletniego zaangażowania w pracę radiową postać A. Stypułkowskiej nie doczekała się pełnego opracowania. Jej przypadek nie jest jedyny, w samej Rozgłośni pracowało lub z nią współpracowało wiele wybitnych kobiet, np. Barbara Palester, Maria Danilewicz-Zielińska, Krystyna Cywińska, Maria Czapska, których okres działania czy współdziałania z RWE pozostaje pominięty w badaniach radiowych w kraju i poza nim.
Retos en la enseñanza de las energías renovables en un mundo digital
Authors: Bellon Monsalve Daniela , Garzon Baquero Jossie Esteban
Published: July 2023

Objetivo: evidenciar los retos más importantes de la transición de educación presencial a educación remota, así como la manera en que se abordaron, desde su análisis en la enseñanza de las energías renovables a nivel de educación superior. Metodología: el enfoque de la investigación es de tipo cualitativo, identificado en una reflexión dinámica de dos sentidos, entre los hechos y su interpretación. Igualmente, la evidencia aportada es de tipo simbólica verbal, en forma de imágenes o audiovisual. Así mismo, la investigación impactó un total de 90 estudiantes, a lo largo de un año de investigación. Resultados: se destacan cuatro elementos y seis retos, los cuales fueron abordados a través de diferentes estrategias didácticas. Conclusión: dichos retos no se limitan a la enseñanza de las energías renovables, sino que son transversales a cualquier asignatura que quiera enseñarse; la forma en que fueron abordados impacta positivamente el proceso de enseñanza-aprendizaje.
A sustainable economy
Authors: Pawlak Joel J.
Published: July 2023

There exists a direct correlation between improvements in standard of living and the consumption of resources. To be able to maintain the standard of living of a modern developed country, society must adapt to an economy based on sustainable processes, energy, and raw materials. The sustainable economy presents itself as a disruptive technology to the traditional economy, which is based largely on non-renewable resources. The issue seems to be more about when will we switch to a sustainable economy, rather than whether we will switch.
Films from spruce galactogluccomannan blended with poly(vinyl alcohol), corn arabonoxylan, and konjac glucomannan
Authors: Mikkonen Kirsi S. , Yadav Madhav P. , Cooke Peter , Willför Stefan , Hicks Kevin B. , Tenkanen Maija
Published: July 2023

The improvement of mechanical properties of spruce galactogluco-mannan (GGM)-based films was sought by blending GGM with each of poly(vinyl alcohol) (PVOH), corn arabinoxylan (cAX), and konjac glucomannan (KGM). The blend ratios were 3:1, 1:1, and 1:3 (w/w), and in addition films were made from each of the polymers alone. Glycerol was used as plasticizer. Adding other polymers increased the elongation at break of GGM blend films. The tensile strength of films increased with increasing amount of PVOH and KGM, but the effect of cAX was the opposite. Dynamic mechanical analysis showed two separate loss modulus peaks for blends of GGM and PVOH, but a single peak for all other films. Optical and scanning electron microscopy confirmed good miscibility of GGM with cAX and KGM. In contrast, films blended from GGM and PVOH showed phase separation when examined by microscopy.
Functionalization pattern of tert-butyldimethyl-silyl cellulose evaluated by NMR spectroscopy
Authors: Heinze Thomas , Pfeifer Annett , Petzold Katrin
Published: July 2023

Tert-butyldimethylsilyl cellulose with a degree of substitution (DS) of up to 2 could be obtained by homogeneous conversion of the biopolymer with tert-butyldimethylchlorosilane in N,N-dimethyl acetamide/LiCl in the presence of imidazole. The cellulose derivatives were characterized in detail by means of two-dimensional NMR spectroscopic techniques including subsequent derivatization of the original polymer by consecu-tive methylation-desilyation-acetylation. The very well resolved NMR spectra indicate that, dependent on the reaction temperature, 2,6-di-O-tert-butyldimethylsilyl moieties are the main repeating units. 3,6-di-O- and 6-mono-O functionalized repeating units were identified in very small amounts if the reaction is carried out at room temperature. Additionally, 2,3,6-tri-O-silylated functions appear if reaction is carried out at temperature of 100°C. Thus, a novel path for regioselective protection of position 2 and 6 for cellulose was established.
In Silico ADMET and Docking Study of Selected Drug Used in Therapy of COVID-19
Authors:   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Jadhav Sagar Ashok , Chavan Payal ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Shete Supriya Suresh ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Patil Dipti Shantisagar ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Kolekar Saroj Dyandev ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Mathews Godfrey Rudolph ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Bhingardev Dipak Babaso ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India, Pawar Pravin Kondiba ,   Dr. Shivajirao Kadam College of Pharmacy, Baganvat, Kasabe Digraj Sangli, Maharashtra - 416305, India
Published: July 2023

Docking is one of the most widely utilized technique used method in structure -based drug design because of its capability to predict the binding conformation of ligands to appropriate target. Ability of binding/ affinity towards the target i.e., bioactive peptides or specific receptor provides strong evidence of binding conformation pattern and affinity for further investigation. Aim- The present study was conducted for evaluation of current API’s potential used in COVID-19. Methods: In-silico molecular docking was performed using softwares such as SWISS ADME, MOLSOFT, MOLINSPIRATION, PYMOL, AUTO-DOCK VINA AND BIOVIA DS VISUALIZER. Results: The current research comprehend the drug likeliness character of selected API’s and their binding affinity with various targets selected by SWISS TARGET PREDICTION. Conclusion: The present investigation suggests that all the targets follow Lipinski rule of five except Remdesivir and Anakinra besides which it possesses enhanced binding affinity toward targets, the binding energy of the protein ligand interaction additionally confirms that the ligand fits into the dynamite pockets which proves to be evident for further in- vivo and in-vitro evaluations.
Scary Truth of Medical Personnel in India
Authors:   Department of Pharmacy Practice, ISF College of Pharmacy, Moga, Punjab-142001, India, Sharma Amit , Osoro Ian ,   Department of Pharmacy Practice, ISF College of Pharmacy, Moga, Punjab-142001, India, Gangwar Ruby ,   Department of Pharmacy Practice, ISF College of Pharmacy, Moga, Punjab-142001, India
Published: July 2023

India is having a lack of adequate medical personnel in a country with a second largest population stands at an alarming level. According to National Health Profile report by the Ministry of Health, Government of India, the situation in India related to the ratio of doctors available and actually practicing is really critical in 2018. The doctor density is far worse in the country’s poorer states. India requires over 7.47 lakh more allopathic doctors to meet World Health Organization (WHO) prescribed norms for the doctor-population ratio.
BEACH PROFILE CHANGES INDUCED BY STORMS
Authors: To Dang Van
Published: July 2023

Along  with  the  introduction  of the  SBEACH  model.  the  storm-induced beach  profile  changes  in  the  Gold  Coast.  Australia,  were simulated  using  SBEACH  with survey  data  collected in  1996.  SBEA CH  qualitatively modeled the profile  changes:  onshore erosion  and  offshore  deposition.  Quantitatively,  SBEACH  did  not  simulate accurately  the shape  of the  measured profile  change  in  spite  of the  correct  estimation  of the  bar  height. Numerical experiments are necessary to  conduct in  order to properly determine  the  empirical parameters for the accurate simulation of profile changes.
GIS BASED LOSS ESTIMATION MODELING FOR FLOODING IN THE CASE OF LONG WAVE AS TSUNAMI
Authors: Lan Nguyen Hong , Tien Nguyen Ngoc
Published: July 2023

This paper presents a GIS basedflood loss estimation modeling approach. Ageneral overview ofsteps in the existingflood loss estimation methodology is given. The existing methodology is limited to a certain categories ofdirect flood damages, such as residential and Jwn-residential buildings and transport damage. Direct damage to infrastructures is estimated as a percentage ofother damage. This is an integrated approach combining a flood inundation simulation model and a loss estimation model. In the loss estimation modeling, direct flo od damages are categorized into three main groups, namely urban, rural and infrastructure damages. GIS is an integral component ofthis approach for pre and post-processing ofthe spatial input and outputs. Finally, a scheme ofthe methodology is described.
Haji Virtual melalui Metaverse untuk Mencegah Penyebaran Covid-19 Perspektif Hukum Islam
Authors: Jatisari Muhammad Akasyah , F Sabrina Diana , Musyafa’ah Nur Lailatul
Published: July 2023

Haji merupakan ibadah wajib bagi kaum muslim, namun karena pandemi Covid-19 maka jumlah jamaah yang melakukan ibadah haji dibatasi. Hal tersebut menjadikan adanya usulan untuk melaksanakan haji secara virtual. Artikel ini bertujuan untuk mengkaji hukum haji virtual melalui metaverse untuk mencegah penyebaran covid-19. Penelitian ini adalah penelitian kualitatif. Data penelitian dihimpun melalui wawancara dan telaah pustaka, yang kemudian dianalisis menggunakan teknik deskriptif analisis. Penelitian ini menyimpulakan bahwa hukum haji virtual melalui metaverse adalah tidak sah karena tidak memenuhi syarat dan rukun haji. Hukum haji virtual tidak sah walaupun haji virtual dilakukan untuk mencegah penyebaran covid-19. Haji virtual tidak sah karena jamaah tidak berada di lokasi ibadah dan tidak merasakan langsung ibadah haji di tanah suci. Meski demikian, pembelajaran haji melalui metaverse diperbolehkan karena mengandung manfaat membantu jamaah belajar haji dengan mudah.
Índice de desenvolvimento da rural das municipalidades: um estudo a partir do Censo Agropecuário de 2006
Authors: Renzi Adriano , Piacenti Carlos Alberto
Published: July 2023

Os aspectos rurais têm apresentado ênfase em decorrência dos novos atributos e inter-relações com o desenvolvimento das regiões. A partir dessa constatação, o artigo objetiva apresentar um novo índice de desenvolvimento rural. Para tanto, o método analítico selecionado foi a análise fatorial com dados oriundos do Censo Agropecuário de 2006, apesar da defasagem temporal nos dados, os resultados indicaram referências consistentes para explicar o desenvolvimento rural. Isso porque a contribuição e os diferenciais decorrem, em primeiro, do conjunto de variáveis que compõe o proposto índice as quais representam as particularidades das dimensões do desenvolvimento econômico (econômica, ambiental, social e demográfica) relacionadas à ruralidade e, em segundo, decorreu do fato de produzir o índice de desenvolvimento econômico da ruralidade, com base na totalidade dos municípios brasileiros e composto por um conjunto de 9 fatores, capaz de aferir e categorizar o nível de desenvolvimento econômico da rural dos municípios e grandes Regiões brasileiras.
ENSURING THE DEVELOPMENT OF EXECUTIVE DISCIPLINE MECHANISMS IN THE PUBLIC SERVICE
Authors:   Taras Shevchenko National University of Kyiv, Ukraine, Larina Nataliia , Yashutin Igor ,   Taras Shevchenko National University of Kyiv, Ukraine
Published: July 2023

The general articulation of the issue and its connection with the important research and practice tasks. The authors described the current state of ensuring the development of executive discipline mechanisms in the public service. The modern state of ensuring executive discipline in the public service has been analysed taking into account modern challenges, in particular, changes in working conditions of public servants during martial law in Ukraine and perspectives of improvement of executive discipline both in this period and in conditions of post-war transformation. The purpose of the article is to reveal scientific and practical concepts of ensuring the development of mechanisms of executive discipline in the public service in conditions of modern challenges and threats; develop suggestions on how to develop modern mechanisms of executive discipline for further improvement of public administration and management in Ukraine. The analysis of the recent publications regarding the issues this article deals with; identification of parts of the general problem that have not been previously addressed. Particular attention is focused on the study and implementation of best practices of foreign experience in domestic public administration. Accession of Ukraine as a candidate to the European community, which now provides large-scale support to Ukraine in the fight against the Russian aggressor, requires updating the basic mechanisms of executive discipline in the public service, such as regulatory, organizational, planning, monitoring, evaluation and quality management. From the point of view of the theory of public administration and Ukraine's transformation processes into European space, it is advisable to expand the classification of the mentioned mechanisms with motivational value, informational and analytical, and digitalization. This will help to consolidate and develop the level of executive discipline in the public service through the self-improvement, self-development and self-fulfilment abilities of public servants. Therefore, the key research outcomes are aimed at improving the development of basic mechanisms for ensuring executive discipline in the public service, widely used in European countries. Conclusions and prospects for further research suggest directions of adaptation of European experience in providing mechanisms for the development of the executive discipline in the public service, which is due to the importance of transformational processes of proper democratic governance in Ukraine, introduction of innovative mechanisms to ensure a high level of executive discipline in the multi-level public administration.
Biomedical Implantable Low-Power Fault-Tolerant Systems
Authors: Talija Resham
Published: July 2023

The study provides an Independent component analysis strategy for filtering out artefacts and decoupling the Electrocardiogram (ECG) from the Ballistocardiogram (BCG) signal. The Independent Component Analysis (ICA) block is used to decompose the original signals (BCG+ECG). An initial 100 iterations are used to update the random values used to define the mixing and un-mixing matrices until convergence is reached. The mean and standard deviation are used to evaluate the filtering performance of a BCG signal. The J-J interval, I-J-K interval, RJ interval, and heart rate are identified in the BCG signals after they have been recovered from the ICA block.We have used these findings to determine if the signal originates from a healthy or unwell individual. The patient's aberrant condition is a strong argument for the use of implanted devices. In this experiment, we use three distinct sensors. The BCG information is collected by placing three sensors at various depths below the flat bed on which the subject is resting. The findings are analysed by taking into account all of the sensor data, and then compared to the outcomes produced by using either of the two sensors alone.
An Active Storage Framework for Utilisation of the Embedded Storage Array's Processing Capabilities
Authors: Manwal Manika
Published: July 2023

The adoption rate of digital products and services has skyrocketed. As the user base grew, so did the volume of data and the need for knowledge. The trend towards storing and processing this influx of data has been upward. Technology has been steadily trending forward, and with that, storage space and computing power. However, typical spinning discs incur a delay in transmitting data to processing components since they are slower than the computer capability. There is a growing Processing - I/O performance gap that contributes to this lag. When it comes to processing large amounts of data, the CPU-I/O performance difference widens. The Processing - I/O performance gap may be reduced with the help of suggested active storage architecture. This study presents a test environment for investigating the effect on application performance.
Digital Solutions and Machine Learning Can Improve Niche Market Reach
Authors: Somosi Zoltán , Hajdú Noémi
Published: July 2023

Digital solutions in marketing can help reach niche markets. Marketers have the greatest opportunity ever to address segments whose needs have not yet been met. Online segmentation techniques allow to better know their characteristics. The aim of this article is to investigate the segmentation and targeting possibilities of the Google Ads system, which helps to explore consumer patterns more deeply. Digital marketing solutions help marketers reach niche markets to maximise the effectiveness of their activities. The goal of this social constructivist research was to find an answer to the question of whether the segmentation and targeting options of the Google Ads advertising system can sufficiently ensure this. To this end, we examined the presence of the “target market category” label in 37 individuals using a face-to-face survey method. The occurrence of the labels and the actual interests often overlapped.
Disciplinary liability for representing a client who abuses the law – a discussion in the context of a disciplinary case of an attorney-at-law, ref. no. OSD/KR 38/17
Authors: Wilk Bartosz
Published: July 2023

Przedmiotem niniejszego opracowania jest rozważenie, czy i w jakich okolicznościach reprezentowanie klienta nadużywającego prawa może stać się podstawą odpowiedzialności
dyscyplinarnej. Zarówno powodem, jak i szerszym tłem rozpatrywanego zagadnienia stało się orzeczenie dyscyplinarne, w którym uznano radcę prawnego za winnego tego, że występował jako pełnomocnik przed wojewódzkimi sądami administracyjnymi na terenie całej Polski w 241 sprawach, zainicjowanych skargami na bezczynność organów w udzieleniu informacji publicznej. W pierwszej kolejności przeprowadzono badanie empiryczne, polegające na analizie dokumentów, wchodzących w skład akt sprawy dyscyplinarnej, które zostały udostępnione na potrzeby prowadzonych badań naukowych. W drugiej kolejności w artykule przedstawiono rozważania prawne na temat podstaw odpowiedzialności, uwieńczone oceną analizowanego rozstrzygnięcia.
Medical professions of public trust – terminological and definitional considerations
Authors: Wrześniewska-Wal Iwona
Published: July 2023

W artykule podjęto próbę usystematyzowania zawodów medycznych, ich podział i rolę w systemie ochrony zdrowia. W badaniach wykorzystano metody dogmatyczne, związane z analizą logiczno-językową oraz wykładnią aktów prawa administracyjnego ze szczególnym uwzględnieniem regulacji dotyczących osób udzielających świadczenia zdrowotne. Wskazano, że brak jednoznacznej definicji zawodu medycznego sprawia, iż trudna staje się ocena coraz szerszych kompetencji poszczególnych zawodów medycznych i przejmowanie części zadań, a tym samym nie jest możliwe ustalenie granic międzyzawodowych. Przedstawiono podstawowe kwestie związane z zawodem reglamentowanym, wolnym i samodzielnym. Z punktu widzenia bezpieczeństwa zdrowotnego zostały przedstawione cechy zawodów zaufania publicznego i krótka analiza dotycząca tworzenia samorządów zawodowych zawodów medycznych jako wspólnej reprezentacji całej profesji.
Communication Beyond Words and Language: Role of Five Senses
Authors: Shankar Mishra Amar
Published: July 2023

Communication has evolved and has been studied as the most important tool of interactions in personal as well as organisational life in the world. As we commonly understand communication as an interplay of words in a particular language, the present article attempts to answer the intriguing question about the origin of the communication and tries to understand its genesis at the metaphysical level. Words and language are representative of some inner thoughts and processes developed based on the perception created in human minds on the basis of what it perceives through sensory organs. The article highlights the role of five senses attributed to the human being in the communication that goes within the oneself. Author finds the root of the communication at ideation, thought and perception level by the interplay of various sense organs. Language oriented communication is just a minor dimension of the realm of communication that a human being experiences through eyes, ears, tongue, touch and nose. Further, author attempts to put the rationale that these five senses can’t communicate effectively when they perform their role in solos rather the interaction amongst them adds contours to the non-verbal expressions and same is manifested through different body languages.
Wolność w orędziach papieża Jana Pawła II na Światowy Dzień Środków Społecznego Przekazu
Authors: Misztal Wojciech
Published: July 2023

W opracowaniu wykorzystano fragmenty corocznych orędzi papieża Jana Pawła II na Światowy Dzień Środków Społecznego Przekazu zawierające w wersji włoskiej termin „libertà” (pol. „wolność”). Nawiązano do ciągle potrzebującej badań i upowszechniania ich wyników historii podejścia do wolności, w tym wolności komunikowania się. Przybliżono raczej mało znane orędzia. Wskazano na przykład, z jaką częstotliwością Jan Paweł II sięga w nich po termin „libertà”, i porównano, co jest ważne dla interpretacji z zastosowaniem tam innych, przedstawiających się jako znaczące, słów. Ponieważ we wskazanych orędziach „libertà” występuje 57 razy, przyjrzano się orędziu z 1981 roku Środki społecznego przekazu w służbie odpowiedzialnej wolności człowieka — dwudziestopięciokrotne użycie, i z 2003 roku Środki społecznego przekazu w służbie autentycznego pokoju w świetle „Pacem in terris” — trzynaście wskazań. Następnie przyjrzano się tym orędziom, w których termin „libertà” pojawia się znacznie rzadziej. Pokazano, że według Jana Pawła II wolność jest niezbędna dla człowieka, także w związku z mediami, oraz jego zaangażowanie na rzecz konkretnych działań, jak też pojmowanie wolności jako cechy człowieka składającej się na jego podobieństwo jako stworzenia do Boga, jako związanej z odpowiedzialnością, z realizacją przykazania miłości, wymagającej obrony, pielęgnowania i rozwijania.
Hermite functions and inner product in Sobolev space
Authors: Boudref Mohamed Ahmed
Published: July 2023

Let us consider the orthogonal Hermite system 〖{φ_2n (x)}〗_(n≥0) of even index defined on (-∞,∞), where
φ_2n (x)=e^(-x^2/2)/(√((2n)!) π^(1/4) 2^n ) H_2n (x),
by H_2n (x) we denote a Hermite polynomial of degree 2n. In this paper, we consider a generalized system {ψ_(r,2n) (x)} with r>0, n≥0 which is orthogonal with respect to the Sobolev type inner product on (-∞,∞), i.e.
〈f,g〉=lim┬(t→-∞)⁡∑_(k=0)^(r-1)▒〖f^((k) ) (t) g^((k) ) (t)+∫_(-∞)^∞▒〖f^((r) ) (x) g^((r) ) (x)ρ(x)dx〗〗
with ρ(x)=e^(-x^2 ), and generated by 〖{φ_2n (x)}〗_(n≥0). The main goal of this work is to study some properties related to the system 〖{ψ_(r,2n) (x)}〗_(n≥0),
ψ_(r,n) (x)=〖(x-a)〗^n/n!,n=0,1,2,…,r-1,
ψ_(r,r+n) (x)=1/(r-1)! ∫_a^b▒〖(x-t)^(r-1) φ_n (t)dt,〗 n=0,1,2,… .
We study the conditions on a function f(x), given in a generalized Hermite orthogonal system, for it to be expandable into a generalized mixed Fourier series as well as the convergence of this Fourier series. The second result of the paper is the proof of a recurrent formula for the system 〖{ψ_(r,2n) (x)}〗_(n≥0). We also discuss the asymptotic properties of these functions, and this concludes our contribution.
The best approximation and the values of the widths of some classes of analytical functions in the weighted Bergman space B_(2,γ)
Authors: Langarshoev Mukhtor R.
Published: July 2023

In the paper, exact inequalities are found for the best approximation of an arbitrary analytic function f in the unit circle by algebraic complex polynomials in terms of the modulus of continuity of the m th order of the r th order derivative f^((r)) in the weighted Bergman space B_(2,γ). Also using the modulus of continuity of the m-th order of the derivative f(r), we introduce a class of functions W_m^((r) ) (h,Φ) analytic in the unit circle and defined by a given majorant Φ, h∈(0,π⁄n], n>r, monotonically increasing on the positive semiaxis. Under certain conditions on the majorant Φ, for the introduced class of functions, the exact values of some known n-widths are calculated. We use methods for solving extremal problems in normed spaces of functions analytic in a circle, as well as the method for estimating from below the n-widths of functional classes in various Banach spaces developed by V.M. Tikhomirov. The results presented in this paper are a continuation and generalization of some earlier results on the best approximations and values of widths in the weighted Bergman space B_(2,γ).
Detection of resistance genes (gyrA,qepA,drf1,drf17) for E.coli in Iraqi aquatic environment ( symbols for genes are italicized (e.g., IGF1) in all the text
Authors: Mahdi Zinah Mohammed , Mahmood Shahad Husham , Baqer Noor Nihad
Published: July 2023

The control of water represents the safe key for fair and optimal use to protect water resources due to human activities, including untreated wastewater, which is considered a carrier of a large number of antibiotic-resistant bacterial species. This study aimed to investigate the prevalence of antibiotic-resistance to E. coli in Tigris River by the presence of resistance genes for aminoglycoside(qepA( ,quinolone (gyrA), and sulfa drugs( dfr1 ,dfr17) due to the frequent use of antibiotics and their release into wastewater of hospitals. Samples were collected from three sites on Tigris River: S1( station wastewater in Adhamiya), S2 (station wastewater in Baghdad Medical city hospital), S3 (station wastewater in Abu Nuwas) from February-July 2021. Out of 67 isolates of bacteria, only 40 isolates of E. coli were detected by Vitek2. The antibiotic-resistance was estimated by the disk diffusion method. All E.coli isolates were tested against 6 antibiotics. The results showed the high resistance antibiotic of E. coli against Ceftazidime 70%, with intermediate resistance to Cefotaxime 47.5%, and low resistance to the sulfa drugs as Trimethoprim 27.5% and quinolones antibiotics as ciprofloxacin 17.5%, aminoglycosides as Amikacin and Gentamycin 5% and 7.5%. Moreover, the results revealed that gyrA gene was detected in 4 isolates (10%) while drf1 and drf17 genes were in 2 isolates of each gene (5%).Whereas qepA gene has not appeared in isolates. In conclusion, the isolates of E.coli from the Tigris River showed low resistance to sulfa drugs and quinolones , aminoglycosides. The resistance genes (gyrA,drf1,drf17) were detected in a few isolates which may be explained by the horizontal transfer of plasmids that carried genes and their distribution among the family  Enterobacteriaceae.
The Mitochondrial Nucleoside Diphosphate Kinase NME4 Mediates Metabolic Reprogramming and Plays a Key Role in Nonalcoholic Fatty Liver Disease Progression
Authors: Li Xu , Xie shaofang , yuan lei , Sui Yue , Feng Shan , Li Hengle
Published: July 2023

Nonalcoholic fatty liver disease (NAFLD) is mainly characterized by excessive fat accumulation in the liver, and it is associated with liver-related complications and adverse systemic diseases. NAFLD has become the most prevalent liver disease; however, effective therapeutic agents for NAFLD are still lacking. We combined clinical data with proteomics and metabolomics data, and found that the mitochondrial nucleoside diphosphate kinase NME4 plays a central role in mitochondrial lipid metabolism. Nme4 is markedly upregulated in mice fed with high-fat diet, and its expression is positively correlated with the level of steatosis. Hepatic deletion of Nme4 suppresses the progression of hepatic steatosis. Further studies demonstrated that NME4 interacts with several key enzymes in coenzyme A metabolism and increases the level of acetyl-CoA and malonyl-CoA, which are the major lipid component of the liver in NAFLD. Increased acetyl-CoA and malonyl-CoA levels lead to increased triglyceride levels and lipid accumulation in the liver. Taken together, these findings reveal that NME4 is a critical regulator of NAFLD progression and a potential therapeutic target for NAFLD.
Abnormal theta oscillation in schizophrenic patients under auditory stimulation: a comparative study
Authors: Zhang Axue , Wei Chenyu , Wan Li
Published: July 2023

Background: There was growing evidences that theta (4-7Hz) power was highly likely to be an indicator of cognitive deficits in schizophrenia. And auditory information processing deficits in schizophrenia were reduced inhibition due to the disruption of the inhibitory mechanisms required to suppress redundant acoustic input. Further assuming that this inhibition was mainly evident in the theta band activity and reflected in the different brain regions.
Method: We chose to use the auditory paradigms to study the change of the theta band power in different brain regions in patients with patients using frequency domain analysis.
Results: The results showed that the sounds always induced abnormal elevation of theta oscillations, and when the frequency of sound stimulation was different, the striking elevation of the induced theta oscillations was reflected in temporal, parietal and central regions. While compared to the other frequencies, the abnormality of theta oscillations had specificity and stability.
Conclusion: This suggested that theta oscillations could serve as a biomarker in schizophrenia research. Future studies in the corresponding brain regions could also provide reference for the selection of the frequency and location for non-invasive treatment in patients with schizophrenia.
Shock Index Creatinine: A New Predictor of Mortality in Acute Coronary Syndrome Patients
Authors: Shariefuddin Widuri , Pramudyo Miftah , Martha Januar
Published: July 2023

Background The Shock Index Creatinine (SIC) scoring is a recently developed tool for risk stratification patients. These updated scoring was already used in ST-Elevation Myocardial Infarction (STEMI) patients. However its utility in predicting outcomes for patients with Acute Coronary Syndrome (ACS) remains unclear. This study aims to evaluate and update the current SIC score to predict in-hospital mortality among patients with ACS.Patients and methods: A retrospective cohort, Single-centered study enrolled 1393 ACS patients aged ≥ 18 years old diagnosed with ACS was conducted between January 2018 to January 2022. Study subjects were analyzed for in-hospital mortality and evaluated using binary linear regression analysis. The area under the curve (AUC) of SIC score was obtain to predict the sensitivity and specificity.Results Multivariate analysis showed that SIC score was significantly associated with in-hospital mortality. High SIC score (SIC ≥ 25) had significantly higher in-hospital mortality (p < 0.001) with odds ratio for (95% CIs) were 2.655 (1.6–4.31). Receiver operating characteristics (ROC) curve analysis determine the predictive power of SIC score for in-hospital mortality. SIC had an acceptable predictive value for in-hospital mortality (AUC = 0.789, 95% CI: 0.748–0.831, p < 0.001). The SIC score for sensitivity and specificity were, respectively, 71.5% and 74.4%, with optimal cutoff of SIC ≥ 25.Conclusion SIC had acceptable predictive value for in-hospital mortality in patients with all ACS spectrums. SIC was a useful parameter for predicting in-hospital mortality, particularly with a score ≥ 25. This is the first study to evaluate SIC in all spectrums of ACS.