bluuebunny/crossref_metadata_2025 huggingface dataset:
Asymmetric Orientation Combination for Reversible and Authenticable Data Hiding of Dual Stego-images
Authors: Lin Jiang-Yi , Horng Ji-Hwei , Chang Chin-Chen , Li Yung-Hui
Published: April 2022

A dual-image-based reversible data hiding (RDH) scheme can conceal secret data into a cover image by creating two steganographic images. These two stego-images can cooperate to extract secret data and restore the cover image. This paper describes a generalization of the orientation combination technology for dual-image-based RDH. We first propose a full search algorithm to find the optimal set of the reversible orientation combinations. Based on the algorithm, the modification range of pixel values can be dynamically enlarged, and thus the embedding capacity becomes adjustable. In addition, an authentication algorithm is provided to detect tampered shadows based on a faithful one. Experimental results confirm that the proposed scheme can produce dual stego-images with a good visual quality. Furthermore, our method provides an adjustable payload. A lot more secret data can be embedded than with state-of-the-art methods, with a satisfactory image quality. Two steganalysis tools are applied to demonstrate the security level of the proposed scheme.
A Method for the Solution of Coupled System of Emden–Fowler–Type Equations
Authors: Alsulami Aishah A. , AL-Mazmumy Mariam , Bakodah Huda O. , Alzaid Nawal
Published: April 2022

A dependable semi-analytical method via the application of a modified Adomian Decomposition Method (ADM) to tackle the coupled system of Emden–Fowler-type equations has been proposed. More precisely, an effective differential operator together with its corresponding inverse is successfully constructed. Moreover, this operator is able to navigate to the closed-form solution easily without resorting to converting the coupled system to a system of Volterra integral equations; as in the case of a well-known reference in the literature. Lastly, the effectiveness of the method is demonstrated on some coupled systems of the governing model, and a speedier convergence rate was noted.
Exploring the Effect of Misinformation on Infectious Disease Transmission
Authors: Mumtaz Nabeela , Green Caroline , Duggan Jim
Published: April 2022

Vaccines are one of the safest medical interventions in history and can protect against infectious diseases and ensure important health benefits. Despite these advantages, health professionals and policymakers face significant challenges in terms of vaccine rollout, as vaccine hesitancy is a global challenge, and varies greatly with context, i.e., place, time, and vaccines. The internet has rapidly become a widely used information source for health-related issues, and a medium where misinformation in relation to vaccines on social media can spread rapidly and influence many. This research models the impact of vaccine confidence on the transmission of infectious diseases. This involves two interacting contagion models, one for the disease itself, and the other for the public’s views on vaccination. Sensitivity analysis and loop impact analysis are used to explore the effects of misinformation and vaccine confidence on the spread of infectious diseases. The analysis indicates that high vaccine confidence has a reinforcing effect on vaccination levels and helps to reduce the spread of an infectious disease. The results show that higher vaccine confidence can mitigate against the impact of misinformation, and by doing so can contribute to the enhanced control of an infectious disease outbreak.
Relationship of Blood and Urinary Manganese Levels with Cognitive Function in Elderly Individuals in the United States by Race/Ethnicity, NHANES 2011–2014
Authors: Barahona Arturo J. , Bursac Zoran , Veledar Emir , Lucchini Roberto , Tieu Kim , Richardson Jason R.
Published: April 2022

Manganese (Mn) is an essential metal with a biphasic relationship with health outcomes. High-level exposure to Mn is associated with manganism, but few data explore the effects of chronic, lower-level Mn on cognitive function in adults. We sought to determine the relationship between blood/urinary manganese levels and cognitive function in elderly individuals using 2011–2014 data from the National Health and Nutrition Examination Survey (NHANES). Weighted multivariate regression models were used to determine correlations, adjusting for several covariates. Blood Mn was inversely associated with the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) immediate learning of new verbal information (p-value = 0.04), but lost significance after adjusting for medical history (p-value = 0.09). In addition, blood Mn was inversely associated with Animal Fluency scores after adjusting for all covariates. Urinary Mn was inversely associated with CERAD immediate learning after adjusting for all covariates (p-value = 0.01) and inversely associated with the Digit Symbol Substitution Test scores (p-value = 0.0002), but lost significance after adjusting for medical history (p-value = 0.13). Upon stratifying by race/ethnicity, other Races and Non-Hispanic (NH)-Blacks had significantly higher blood Mn levels when compared to NH-Whites. Collectively, these findings suggest that increased blood and urinary Mn levels are associated with poorer cognitive function in an elderly US population.
Co-Exposure of Nanopolystyrene and Other Environmental Contaminants—Their Toxic Effects on the Survival and Reproduction of Enchytraeus crypticus
Authors: Mendes Luís A. , Barreto Angela , Santos Joana , Amorim Mónica J. B. , Maria Vera L.
Published: April 2022

Plastics in all shapes and sizes have become widespread across ecosystems due to intense anthropogenic use. As such, they can interact with other contaminants that accumulate in the terrestrial environment, such as pharmaceuticals, metals or nanomaterials (NMs). These interactions can potentiate combined toxic effects in the exposed soil organisms, with hazardous long-term consequences to the full ecosystem. In the present study, a terrestrial model species, Enchytraeus crypticus (oligochaeta), was exposed through contaminated soil with nanopolystyrene (representative of nanoplastics (NPls)), alone and in combination with diphenhydramine (DPH, representative of pharmaceuticals), silver nitrate (AgNO3, representative of metals) and vanadium nanoparticles (VNPs, representative of NMs). AgNO3 and VNPs decreased E. crypticus reproduction at 50 mg/kg, regardless of the presence of NPls. Moreover, at the same concentration, both single and combined VNP exposures decreased the E. crypticus survival. On the other hand, DPH and NPls individually caused no effect on organisms’ survival and reproduction. However, the combination of DPH (10 and 50 mg/kg) with 300 mg NPls/kg induced a decrease in reproduction, showing a relevant interaction between the two contaminants (synergism). Our findings indicate that the NPls can play a role as vectors for other contaminants and can potentiate the effects of pharmaceuticals, such as DPH, even at low and sub-lethal concentrations, highlighting the negative impact of mixtures of contaminants (including NPls) on soil systems.
Quantitative Estimation of Synergistic Toxicity of Cu and Zn on Growth of Arabidopsis thaliana by Isobolographic Method
Authors: Bae Bumhan , Park Hyesun , Kang Sua
Published: April 2022

Heavy metal is one of the most frequent soil contaminants and contaminated soils generally include numerous metals. Although exposure to multiple metals may increase the toxicity to humans and ecosystems, only additive effects are considered in the risk assessment. In this study, the synergistic effect of heavy metals (Cu and Zn) on a model plant, Arabidopsis thaliana, was quantified by the isobolographic method. The plant was cultured via the growth assay method on a plant agar containing individual heavy metals or combinations of Cu + Zn in a growth chamber. The concentration of Cu varied by eight levels from 0 to 200 μM and the concentration of Zn also varied by eight levels from 0 to 400 μM. In the combination of metals, each of the three levels of Cu (25–75 μM) and Zn (20–100 μM) were applied. After 8 days, plants were harvested for root/shoot weight and measured for leaf chlorophyll and carotenoid content. The primary and secondary root elongation of A. thaliana was estimated using image analysis to calculate total root length. The EC50 values of Cu and Zn on A. thaliana, based on the total root length, were 40.0 and 76.4 μM, respectively. When two heavy metals were administered in combination, the EC values decreased less than those of the individual metals. The average value of the combination index was 0.6, proving the synergistic toxic effect on the root growth of A. Thaliana. As a result, the isobolograhic method is a useful tool for estimating the quantitative toxic effect of chemicals on plants.
Molecular Evidence on the Inhibitory Potential of Metformin against Chlorpyrifos-Induced Neurotoxicity
Authors: Daniali Marzieh , Baeeri Maryam , Farhadi Ramtin , Gholami Mahdi , Hassani Shokoufeh , Navaei-Nigjeh Mona , Rahimifard Mahban , Abdollahi Mohammad
Published: April 2022

Chlorpyrifos (CPF) is an organophosphorus (OP) pesticide, resulting in various health complications as the result of ingestion, inhalation, or skin absorption, and leads to DNA damage and increased oxidative stress. Metformin, derived from Galega officinalis, is reported to have anti-inflammatory and anti-apoptotic properties; thus, this study aimed to investigate the beneficial role of metformin in neurotoxicity induced by sub-acute exposure to CPF in Wistar rats. In this study, animals were divided into nine groups and were treated with different combinations of metformin and CPF. Following the 28 days of CPF and metformin administration, brain tissues were separated. The levels of inflammatory biomarkers such as tumor necrosis factor alpha (TNFα) and interleukin 1β (IL-1β), as well as the expression of 5HT1 and 5HT2 genes, were analyzed. Moreover, the levels of malondialdehyde (MDA), reactive oxygen species (ROS), and the ADP/ATP ratio, in addition to the activity of acetylcholinesterase (AChE) and superoxide dismutase (SOD), were tested through in vitro experiments. This study demonstrated the potential role of metformin in alleviating the mentioned biomarkers, which can be altered negatively as a result of CPF toxicity. Moreover, metformin showed protective potential in modulating inflammation, as well as oxidative stress, the expression of genes, and histological analysis, in a concentration-dependent manner.
A Mesofractal Model of Interstellar Cloudiness
Authors: Uchaikin Vladimir V. , Kozhemyakin Ilya I.
Published: April 2022

The interstellar medium (ISM), serving as a background for the propagation of cosmic rays (CRs) and other information carriers, has a complex ragged structure. Being chaotically scattered over interstellar space, together with the magnetic field perturbations frozen in them, CRs are connected with each other by a network of magnetic field lines creating long-range correlations of a power-law type, similar to those observed in the spatial distribution of galaxies. These lines solving interstellar transfer problems require the choice of an ISM model, adequately and concisely representing their statistical properties. This article discusses one such model, the Uchaikin–Zolotarev model: a four-parameter approximation of the power spectrum spatial correlations, derived from the generalized Ornstein–Zernike equation. The numerical analysis confirmed that this approximation satisfactorily agrees with the numerical data obtained in the quasi-linear model of plasma turbulence.
The Solar-Electric Sail: Application to Interstellar Migration and Consequences for SETI
Authors: Matloff Gregory Lee
Published: April 2022

The Solar-Electric Sail accelerates by reflecting positively charged solar wind ions. If it is used to propel an interstellar migration mission, its interstellar cruise velocity relative to the home star cannot exceed the solar wind velocity. In an effort to analytically determine interstellar cruise velocity for a 107 kg generation ship, a constant solar wind velocity within the heliosphere of a Sun-like star of 600 km/s is assumed. The solar wind proton density at 1 AU is also considered constant at 10 protons per cubic centimeter. Solar wind density is assumed to decrease with the inverse square of solar distance. It is shown that, to maintain sufficient acceleration to achieve an interstellar cruise velocity about 70% of the solar wind velocity, the radius of the sail’s electric field is enormous—greater than 105 km. Because the solar wind velocity and density are not constant, field strength must be varied rapidly to compensate for solar wind variation. Although not competitive with the ultimate theoretical performance of solar-photon sail propelled migrations departing from Sun-like stars, the solar-electric sail might be superior in this application for migration from dim K and M main sequence stars. Such migrations conducted during close stellar encounters might have durations < 1000 terrestrial years. If only a tiny fraction of M dwarf stars host star-faring civilizations, a significant fraction of Milky Way galaxy planetary systems may have been inhabited, even if no major advances over currently postulated interstellar transportation systems are postulated. SETI theoreticians should consider this when estimating the effects of interstellar colonization.
The Role of COVID-19 Vaccinal Status in Admitted Children during OMICRON Variant Circulation in Rio de Janeiro, City—Preliminary Report
Authors: Araujo da Silva André , de Carvalho Bernardo , Esteves Monica , Teixeira Cristiane , Souza Cristina
Published: April 2022

Objective: To evaluate COVID-19 vaccination status in admitted children in 2020–2021 and during the OMICRON variant circulation (2022), a period when children older than 12 years of age had received two doses of COVID-19 vaccines. Design: An observational retrospective study. Patients with confirmed COVID-19 were compared in two different periods: 2020–2021 when adolescents aged 12–18 years had not received the complete COVID-19 vaccine, and 2022 when children older than 12 years had received the complete Pfizer-BioNTech vaccine scheme. Setting: Two pediatric hospitals in Rio de Janeiro city. Patients: Children aged < 18 years with confirmed COVID-19. Intervention: None. Main outcome: Vaccination status for COVID-19 on admission. Results: In total, 300 patients were admitted with confirmed COVID-19 (240 in 2020–2021 and 60 in 2022). The distribution of patients according to the age-groups was: 0–2 years (33.3% in 2020–2021 and 53.4% in 2022), 2–5 years (21.7% in 2020–2021 and 10% in 2022), 5–11 years (29.2% in 2020–2021 and 28.3% in 2022), and 12–18 years (15.8% in 2020–2021 and 8.3% in 2022) (p = 0.076). The median length of stay was six days in 2020–2021 and six days in 2022 (p = 0.423). We verified six deaths in the first analysis period and one death in the second one (p = 0.894). Of the 60 children admitted in 2022, 58 (96.7%) did not receive the complete COVID-19 vaccine scheme available. Conclusions: We verified in a “real-world condition” the ability of the Pfizer-BioNTech vaccine to prevent hospitalization in children over 12 years of age.
Gene Cloning, Tissue Expression Profiles and Antiviral Activities of Interferon-β from Two Chinese Miniature Pig Breeds
Authors: Noor Aziz Ullah , Du Zhanyu , Song Chengyi , Lu Huipeng , Zhou Xiaohui , Liu Xiaoming , Zhang Xinyu , Sun Huaichang
Published: April 2022

The porcine interferon (PoIFN) complex represents an ideal model for studying IFN evolution which has resulted from viral pressure during domestication. Bama and Banna miniature pigs are the two Chinese miniature pig breeds that have been developed as laboratory animal models for studying virus infection, pathogenesis, and vaccine evaluation. However, the PoIFN complex of such miniature pig breeds remains to be studied. In the present study, we cloned PoIFN-β genes from Bama and Banna miniature pigs, detected their PoIFN-β tissue expression profiles, prepared recombinant PoIFN-β (rPoIFN-β) using the E. coli expression system, and measured their antiviral activities against three different pig viruses. At the amino acid sequence level, PoIFN-βs of the two miniature pig breeds were identical, which shared 100% identity with that of Congjiang Xiang pigs, 99.4–100% identity with that of domestic pigs, and 99.5% identity with that of three species of African wild boars. The tissue expression profiles of PoIFN-β mRNA differed not only between the two miniature pig breeds but between miniature pigs and domestic pigs as well. The four promoter domains of PoIFN-β of the two miniature pig breeds were identical with that of humans, domestic pigs, and three species of African wild boars. The recombinant PoIFN-β prepared from the two miniature pig breeds showed dose-dependent pre-infection and post-infection antiviral activities against vesicular stomatitis virus, porcine respiratory and reproductive syndrome virus, and pig pseudorabies virus. This study provided evidence for the high sequence conservation of PoIFN-β genes within the Suidae family with different tissue expression profiles and antiviral activities.
The Importance of Complementary PCR Analysis in Addition to Serological Testing for the Detection of Transmission Sources of Brucella spp. in Greek Ruminants
Authors: Batrinou Anthimia , Strati Irini F. , Tsantes Andreas G. , Papaparaskevas Joseph , Dimou Ioannis , Vourvidis Dimitrios , Kyrma Anna , Antonopoulos Dionysis , Halvatsiotis Panagiotis , Houhoula Dimitra
Published: April 2022

The early and accurate diagnosis of brucellosis, a ubiquitous zoonotic infection, is significant in preventing disease transmission. This study aimed to assess the infection rate of Brucella spp. in ruminants and to evaluate the agreement between a serological test and a molecular method for the detection of infected cases. Blood and milk samples of 136 ruminants were analyzed using two laboratory methods: the Rose Bengal plate (RBP) test to detect B. abortus and B. melitensis antibodies and the molecular polymerase chain reaction (PCR) method for the presence of bacterial DNA. The agreement between the methods was assessed using the kappa statistic. Based on the RBP test, there were 12 (8.8%) seropositive animals (10 sheep and 2 cows), while 2 (1.4%) samples were positive on PCR analysis. The positive PCR samples were from seronegative cow samples on RBP testing. There was slight agreement (k = −0.02) between the two methods, which was not statistically significant. Our results indicate that complementary molecular methods are useful to detect the bacteria in infected animals that are seronegative due to an early stage of infection. Therefore, a combination of molecular methods and serological tests can be applied to detect brucellosis in ruminants efficiently.
Treatment of Canine Oral Melanomas: A Critical Review of the Literature
Authors: Pazzi Paolo , Steenkamp Gerhard , Rixon Anouska J.
Published: April 2022

Critical appraisal of the available literature for the treatment of canine oral malignant melanoma (OMM) is lacking. This critical review aimed to evaluate the current literature and provide treatment recommendations and possible suggestions for future canine OMM research. PubMed, Web of Science and Google Scholar were searched in June 2021, for terms relevant to treatment of OMM. Inclusion and exclusion criteria were applied and information on clinical response and outcome extracted. Eighty-one studies were included. The overall level of evidence supporting the various canine OMM treatment options was low. The majority of studies included confounding treatment modalities and lacked randomization, control groups and consistency in reporting clinical response and outcomes. Within these limitations, surgery remains the mainstay of therapy. Adjunctive radiotherapy provided good local control and improved median survival times (MST), chemotherapy did not offer survival benefit beyond that of surgery, while electrochemotherapy may offer a potential alternative to radiotherapy. Immunotherapy holds the most promise in extending MST in the surgical adjunctive setting, in particular the combination of gene therapy and autologous vaccination. Prospective, randomized, double-blinded clinical trials, with a lack of confounding factors and reporting based on established guidelines would allow comparison and recommendations for the treatment of canine OMM.
Determination of the Variation of the Geometric and Dynamic Parameters of the Floodplain Vegetation
Authors: Walczak Natalia , Walczak Zbigniew , Ficner Tomasz
Published: April 2022

Floodplain vegetation is characterized by its ability to resist deformation and destruction and to deform elastically and plastically under the influence of external mechanical forces. The force of water that presses on the plant induces stress and deformation in it, but once the force is removed, the elastic properties of the vegetation return it to its original state. It regains its original size, shape, and volume. In this paper, the deflection arrow was analysed based on the field tests conducted, and then the modulus of elasticity of natural shrub vegetation was determined. Measurements were made at different plant heights. Analysis was carried out at different growing periods to estimate the variation of plant elasticity with growth, development, and season. The results confirm the loss of flexibility during winter for all the shrubs analysed. Based on the measurements carried out, the elastic modulus E of the shoots was estimated. The average modulus of elasticity ranged from about 2100 to about 4000 MPa and showed high variability, reaching even µ = 50%, both within a given shrub and depending on the measurement season. The results presented here indicate a high natural variability of mechanical parameters even within the same plant.
Migration Law of LNAPLs in the Groundwater Level Fluctuation Zone Affected by Freezing and Thawing
Authors: Zhou Jing , Pan Minghao , Chang Chuping , Wang Ao , Wang Yongqi , Lyu Hang
Published: April 2022

Freezing and thawing can cause dynamic fluctuations of the groundwater level, resulting in the migration and retention of LNAPLs. However, this process is difficult to observe visually, and a suitable simulation method for its quantitative calculation is lacking. In this study, a numerical simulation is established by coupling the HYDRUS-1D software and the TOUGH program to realize dynamic simulation of the entire process of soil temperature changes, water migration, water level fluctuation, and redistribution of LNAPLs during the freeze–thaw process. The results of the study show that the process of soil freezing and thawing causes water migration, which in turn causes groundwater level fluctuation, leading to the migration and redistribution of LNAPLs within the water level fluctuation zone. In this process, the soil particle size and porosity control the response degree and speed of the water level under freezing and thawing and the spatiotemporal distribution of LNAPLs by affecting the soil temperature, capillary force, and water migration. The migration ability of free LNAPLs is determined by their own density and viscosity; the retention of residual LNAPLs is affected by soil porosity and permeability as well as LNAPL viscosity. The results of this study can not only be used to develop a simulation method for the migration and retention mechanism of LNAPLs in cold regions but also serve as a scientific and theoretical basis for LNAPL pollution control in seasonal frozen soil regions.
LA OBLIGACIÓN DE LOS SINDICATOS DE GARANTIZAR LA TRANSPARENCIA SINDICAL
Authors: Méndez-Díaz Elia
Published: April 2022

Los sindicatos son personas morales, que adquieren personalidad jurídica al registrarse ante la autoridad laboral competente y los cuales ejercen recursos económicos y patrimoniales en cumplimiento de sus intereses en beneficio de la base trabajadora, por lo que se encuentran obligados por la Ley laboral en conjunto con la Ley General de Transparencia y Acceso a la Información Pública, para publicar toda la información relacionada con su registro y sus actuaciones, así como rendir un informe a sus agremiados sobre el uso del patrimonio sindical y las cuotas que se le descuentan de sus salarios, lo cual analizaremos de un modo analítico y propositivo, a través del realismo jurídico.
La situación tutelar de los niños transgresores de la Ley Penal en el Perú
Authors: Zapata Mogollón Francisco Magno
Published: April 2022

La situación tutelar de los menores infractores a la Ley Penal (código penal y código del niño en Perú), es una realidad latente, que un gran número de menores afronta, por la presunta comisión de una infracción, sin embargo, el Estado peruano no cumple con la protección integral al menor, vulnerando así, el principio marco del interés superior del niño y del adolescente. El presente estudio tuvo como objetivo describir la actual regulación de la situación tutelar de los menores en Perú, que se encuentran en conflicto con la normatividad penal, teniendo como propósito identificar las condiciones de tratamiento de un grupo humano vulnerable y evidenciar categorías emergentes. Esta investigación fue de tipo descriptiva, basada en un paradigma sociocrítico de revisión de las reglas de Beijing de administración de justicia a menores, adoptadas por la Asamblea General de las Naciones Unidas desde el año 1985, integradas al área de familia del Ministerio Público (Fiscalías de Familia), conteniendo como informantes claves a Jueces y fiscales especializados en Familia, así como Abogados de la Unidad de Protección Especial de menores. El método utilizado fue el inductivo con enfoque cualitativo y descriptivo. Los resultados advierten categorías emergentes desde la interpretación de la jurisprudencia internacional de la doctrina de la protección integral, caracterizada por señalar al niño o adolescente como sujeto pleno de derechos, en consonancia con la Convención de los Derechos del Niño.
Immune Status of Bighead Catfish (Clarias macrocephalus Günther, 1864) Crossbreeds Between Wild and Domesticated Strains and Their Response to Challenge With Aeromonas hydrophila
Authors:   College of Aquaculture and Fisheries, Can Tho University, Can Tho City, Vietnam, HANG BUI THI BICH , YEN DUONG THUY
Published: April 2022

Aeromonas hydrophila is a major pathogen causing septicemic disease and high mortality in cultured bighead catfish, Clarias macrocephalus Günther, 1864. Crossbreeding for enhanced disease resistance may help alleviate the infection. This study aimed to evaluate the crossbreeding effects of bighead catfish from three broodstock sources, including one domesticated strain (Can Tho - CT) and two wild strains (Ca Mau - CM and Hau Giang - HG), on the innate immune response. Eight diallel crosses (excluding HG × CT) were reared in tanks for 100 days to the juvenile stage for use in this study. Forty-five bighead catfish juveniles of similar sizes, 4.5–6.1 g, were sampled from each cross to evaluate the immune response and stress indicators. Thirty fish from each cross were challenged with A. hydrophila. The results showed that innate immune responses of domesticated CT strains were higher than wild strains (HG and CM). Higher values of white blood cells, phagocytic activity, and lysozyme activity were observed in CT × CT and CT × CM crosses. These crosses had significantly lower cortisol levels and lower mortality rates of 40 % (CT × CT) and 43.3 % (CT × CM) after being challenged with A. hydrophila compared to the other crosses. The results demonstrate that domesticated CT strain and crossbreeding between CT and CM wild strains could improve the innate immune system and resistance to A. hydrophila. The innate immune responses of the domesticated CT strain were higher than wild strains (HG and CM).
PENINGKATAN KUALITAS HIDUP LANSIA MELALUI PEMBERDAYAAN LANSIA PRODUKTIF, GAYA HIDUP SEHAT DAN AKTIF
Authors: Indrayogi Indrayogi , Priyono Ali , Asyisya Padila
Published: April 2022

In nation building, health is one of the basic and important elements. Poor health conditions cause humans to be unable to regulate their own lifestyle and development in their area. As an emerging physiological syndrome in public health, frailty is a predictive factor of negative health outcomes, such as increased risk of death, decreased activities of daily living. So, in this Community Service activity, it aims to form a community that has knowledge and abilities, especially the elderly, especially in the health sector. The village that will be assisted by Community Service is Banjaransari Village, Cikijing District, Majalengka Regency, this village has more than 50 people (residents aged over 65 years) and is one of the villages with a large elderly population. The method used in this service is quantitative descriptive. The service is carried out in the form of implementing a healthy and active lifestyle: Elderly gymnastics, memory exercises and games, health education for the elderly. through how to form a healthy soul, improve the abilities and skills of the elderly, especially in Majalengka, namely Banjaransari village. The conclusion is that elderly parents have a productive spirit by doing activities to fill their spare time with physical activities such as elderly gymnastics, and making Family Medicinal Plants (Toga) in flower pots or in the yard. and set an example for the surrounding community to build their village for a better future for the nation and state.

Key words: Quality of Life; Productive Old Age; Healthy and Active Lifestyle
PEMETAAN SEBARAN DAYA TARIK WISATA DI DESA BULO SEBAGAI KAWASAN AGROWISATA KAB POLEWALI MANDAR SULAWESI BARAT
Authors: Kasim Muh , Yahya Muh , Ridwan Masri
Published: April 2022

The purpose of this study was to map the distribution of tourist attractions in the agro-tourism area of Bulo Village, Bulo District, Polewali Mandar Regency. After careful scrutiny, it turns out that Bulo Agrotourism has entered as a leading tourist attraction in Polewali Mandar Regency. The research was conducted through a field survey using Garmin GPS to determine the location of tourist objects and area boundaries, data processing was carried out using ArcGIS 10.8. The data processing produces attribute data in the form of spatial and coordinate data, so that 6 (six) objects can be mapped including Anugerah Bulo Hill, Tapenangi Durian Garden, Bulo Botanical Garden, Lemo Nipi Hill, Uhai Sibali Peak and Senayan Hill. Meanwhile, based on the 3 (three) components of tourism which include Attractions, Accessibility and tourist activities that really need to be addressed are the accessibility components, including transportation service facilities so that tourists can visit agro-tourism at any time and feel comfortable and safe, because the road conditions to the location are still in pioneering, so that the policy makers should immediately fix the road facilities to each tourist attraction..
Photovoltaic microgeneration (RES) in selected major cities in Silesian Voivodeship
Authors: Halama Arkadiusz , Majorek Agnieszka
Published: April 2022

The impact of climate change on the economy and environment humans live in has increased, leading to a relatively quick intensification of the effort to reduce the environmental footprint of the civilisation. The push to establish a sustainable energy economy has become one of the primary challenges today. A sustainable energy economy should ensure energy security, reduce energy poverty, and contribute to lower greenhouse gas emissions. Poland is facing considerable challenges relevant to the objectives of EU policy, particularly the Fit for 55 package, which cannot be achieved without renewable energy sources. The most popular renewable energy source in Poland is solar energy. Apart from its obvious advantages, the use of distributed photovoltaic generation (including microgeneration) entails the need for transmission grid upgrades. The paper’s objective was to assess the RES potential of Poland through an analysis of the steps the state took and the progress of its targets. The empirical part focuses on the assessment of the use of the solar energy potential (in photovoltaic microgeneration) in cities with district rights in Silesian Voivodeship, Poland, from 2014 to 2020. The study employs selected cartographic representation, comparative analysis, in-depth case study, and spatial analysis methods. The calculations involved data from Tauron Dystrybucja SA on the number of microgeneration systems in the cities, Database of Topographic Objects, Local Data Bank of the Central Statistical Office of Poland and Eurostat.
Financial economy of communes with a large forest area - example of rural communes of the Podlaskie Voivodeship
Authors: Koloszko-Chomentowska Zofia
Published: April 2022

The financial situation of rural municipalities in the Podlaskie voivodeship, which a large forest areas was discussed. The problem that was undertaken was addressed on the basis of mass statistical data from the Central Statistical Office (GUS), and analysis covers the years 2016-2019. Assessment of the financial economy was carried out based on budget, per capita and debt liability indicators. Correlation analysis was conducted to determine relationships between indicators. Both incomes and expenses per capita are lower than the average for Polish rural communes. Large differences in the values of other indicators are present between groups, which arises from, among other things, the policy conducted by local authorities. Income from forestry tax supplement other income from taxation of natural persons’ property. The share of income from forestry tax is similar to the share of income from agricultural tax, and even higher in certain municipalities.
Evaluation of the use of cogeneration bonus as a support mechanism for the transformation of the heating system in Poland in 2019-2020
Authors: Adamik Piotr
Published: April 2022

The development of cogeneration is an element of the transformation of the Polish heating sector. Consequently, the state applies various subsidy mechanisms. One of them is the cogeneration bonus, which is designed to stimulate investment in high-efficiency cogeneration. It consists in subsidizing the generated electricity to entities that won the cogeneration bonus auction and then made investments in new cogeneration engines. The purpose of this paper is to evaluate the use of the cogeneration bonus. The thesis assumes that the cogeneration bonus, despite its supportive nature, is not used by investors. This is evidenced by the low level of contracting of subsidies available in individual auctions. To achieve the objective of the study, the ratio of the volume of contracted subsidies in the cogeneration bonus auctions to the volume available for contracting in individual auctions was analyzed. The author has analyzed: the results of the auction for cogeneration bonus, sector reports, CO2 emission price, types of fuel as well as aggregated financial data of Polish heat plants. The research has an implication character, confirming lack of adequacy of cogeneration bonus to financial situation of potential investors.
Klasifikasi Jenis Kacang-Kacangan Berdasarkan Tekstur Menggunakan Jaringan Syaraf Tiruan
Authors: Al Rivan Muhammad Ezar , Rachmat Nur , Ayustin Monica Rizki
Published: April 2022

Classification of types of beans is done on red beans, green beans, and peanuts. Texture features are obtained using the Gray Level Co-occurrence Matrix (GLCM) algorithm. The algorithm used to do the classification is Artificial Neural Networks (ANN). Experiments carried out with 3 different numbers of neurons in the hidden layer. Also, there are 17 types of training functions used. Each experiment scenario was repeated 5 times. Based on the experimental scenario, the best results are 99.8% for accuracy, 99.6% for precision and 99.8% for recall using 20 neurons in the hidden layer.
The Analysis And Design of School Health Unit Information System
Authors: Absari Dhiani Tresna , Liliana Liliana
Published: April 2022

Keberhasilan pendidikan ditunjang oleh aspek akademis maupun non akademis. Untuk mewujudkan keberhasilan pendidikan ini, maka sekolah harus memiliki kemitraan yang baik dengan orang tua terhadap kedua aspek tersebut, termasuk kesehatan siswa. Seringkali Unit Kesehatan Siswa (UKS) dianggap sebagai supporting system dalam proses bisnis di sekolah, sehingga kurang mendapatkan perhatian yang serius. Saat ini, cukup banyak kegiatan di UKS yang dilakukan secara paper-based, atau bahkan mengandalkan ingatan petugas, seperti ijin tidak masuk sekolah, penggunaan obat, informasi kegiatan penyuluhan, kejadian yang menimpa anak di sekolah dan kegiatan lainnya. Informasi tersebut memiliki kemungkinan tidak diterima dengan baik oleh orang tua, seperti form catatan hilang, atau terlambat diterima oleh orang tua. Oleh karena itu, dibutuhkan suatu sistem yang memungkinkan orang tua dan pihak sekolah berinteraksi secara online, terkait kondisi kesehatan anak selama di sekolah dan sebaliknya. Sistem ini dirancang dengan dua platform, yaitu web dan mobile; dan menggunakan satu database, sehingga sistem tetap terintegrasi dan dapat diakses dengan mudah oleh pihak sekolah maupun orang tua. Dengan demikian, sistem ini diharapkan dapat meningkatkan kualitas komunikasi antar sekolah dan orang tua.
Pemodelan CNN Untuk Deteksi Emosi Berbasis Speech Bahasa Indonesia
Authors: Aini Yulistia Khoirotul , Santoso Tri Budi , Dutono Titon
Published: April 2022

Perkembangan teknologi menunjukkan semakin banyak kebutuhan perangkat yang mampu menjalankan interaksi antara manusia dengan computer secara cerdas. Satu contohnya adalah sistem pengenalan emosi dengan computer. Di dalamnya diperlukan kemampuan untuk melakukan pengenalan, penafsiran, dan memberikan respons emosi yang diekspresikan dalam ucapan. Tetapi sampai saat ini penelilitan speech emotion recognition (SER) yang berbasis bahasa Indonesia masih sangat sedikit. Hal ini disebabkan keterbatasan korpus data berbahasa Indonesia untuk SER. Pada penelitian ini dibuat sistem SER dengan mengambil dataset dari TV series berbahasa Indonesia. Sistem dirancang dengan kemampuan untuk  melakukan proses klasifikasi emosi, yaitu empat kelas label emosi  marah, senang, netral dan sedih. Untuk implementasinya digunakan metode deep learning, yang dalam hal ini dipilih metode CNN. Pada sistem ini input berupa kombinasi dari tiga fitur, yaitu MFCC, frekuensi fundamental, dan RMSE. Dari eksperimen yang telah dijalankan telah diperoleh hasil terbaik untuk sistem SER berbahasa Indonesia dengan menggunakan input MFCC + frekuensi fundamental, yang menunjukkan tingkat akurasi sebesar 85%. Sedangkan ketika hanya menggunakan input MFCC memiliki tingkat akurasi sampai 83%. Sementara itu ketika dipaksakan dengan kombinasi ketiga input MFCC+ F0+ RMSE mengalami penurunan kinerja dan hanya mencapai akurasi 78% ,dan akurasi terendah menggunakan fitur MFCC + RMSE yaitu 72%. Dari study awal ini diharapkan mampu memberikan gambaran bagi para peneliti di bidang SER, tentang  bagaimana memilih fitur sinyal wicara sebagai input di dalam pengujian dan mempermudah untuk langkah pengembangan penelitiannya.
Sobre escolhas e construção de caminhos, aprendendo com uma narrativa singular
Authors: Sátyro Maia Doralice , Araújo Gonçalves Luiz Antônio
Published: April 2022

O que nasceu como uma tentativa de aproximar pesquisadores de diversas áreas, de mobilizar os membros do Conselho Editorial da SertãoCult na elaboração de um material que exprimisse a capacidade da editora em produzir obras com qualidade técnica e com relevância acadêmica, tornou-se um sucesso logo em sua primeira edição. Após o lançamento do volume Diálogos sobre a Ditadura, que reuniu alguns dos maiores pesquisadores sobre a temática no Brasil, a série Território Científico  chega ao seu segundo volume elaborado a partir de uma parceria com os profissionais ligados ao Seminário da Rede de Pesquisadores sobre as Cidades Médias (ReCiMe). Eis a obra “Trajetórias de pesquisadores e os estudos das cidades médias em perspectiva”. É gratificante concluirmos mais esta contribuição para a comunidade científica, apresentando as trajetórias de algumas das maiores referências da Geografia Urbana brasileira, que no contexto da pandemia da Covid-19 ficaram tão fisicamente distantes, mas nunca tão próximos, unidos através da tecnologia, que permitiu a troca de experiências com colegas de diferentes regiões do país. Passados alguns meses da realização das entrevistas, finalmente a pandemia dá mostras de arrefecimento. O isolamento que tanto nos custou, começa a dar lugar a reencontros presenciais e estas entrevistas, mais do que um relato de experiências de pesquisa, passam a compor um registro histórico de como a crise sanitária afetou toda a nossa sociedade. Se  a  produção  científica  segue  sendo  alvo  de  constantes  ataques  e aqueles que se dedicam a ela ainda são encarados quase como inimigos do Estado, é mais do que pertinente, mas necessário que todos aqueles que acreditam na educação, na ciência, no conhecimento se unam e abracem projetos que busquem aproximar essa produção e o público em geral. Mais um livro se junta à nossa série, nos deixando ainda mais orgulhosos e empenhados em nossa defesa incondicional da ciência. Que venham os próximos volumes!
Results of medical and economic efficiency assessment of the gastroduodenite prevention program for retirement age patients with essential arterial hypertension, which took part in the program "Affordable medicines"
Authors: Rudenko A.A.
Published: April 2022

The medical and economic effectiveness of approaches to the prevention of gastroduodenitis in patients of retirement age with essential hypertension has been insufficiently studied. This fact necessitated this study. A combined (retrospective-prospective) study of gastroduodenitis prevention programs for retirement age patients with essential hypertension who are taking drugs under the "Affordable Medicines" program was conducted. A new theoretical model for assessing the medical and economic effectiveness of the gastroduodenitis prevention program in patients with essential hypertension with key parameters "incremental cost – effectiveness ratio" (ICER) and "incremental benefit – cost ratio" (IBCR) has been developed. The effectiveness of the proposed program was evaluated. The main factors of lifestyle and treatment that affect the development and exacerbation of gastroduodenitis in this category of patients are identified. The risks of gastroduodenitis due to non-steroidal anti-inflammatory drugs, the presence and absence of compliance, age and sex of patients, living alone (without a family), which indicate ways to improve prevention programs and determine the nature of recommendations for patients on lifestyle and treatment of hypertension. Evaluation of the effectiveness of the proposed prevention program on the criteria of ICER and IBCR allowed to determine the positive additional effect of participation in the reimbursement program, compliance, male gender, identified patient income levels at which increasing costs of prevention programs has greater economic effect. It is recommended to use the results of the study to improve the programs of prevention of hypertension in patients with hypertension at the stage of primary health care, including the cost of individual items of expenditure of the program "Affordable Medicines".

Keywords: prevention program, risk, clinical and economic evaluation, costs-effectiveness, essential hypertension, gastroduodenitis.
Clinical evaluation of the treatment complex of acute odontogenic periostitis in children on the base of diffused non-toxic goiter
Authors: Vitkovskyi O.O.
Published: April 2022

Inflammatory diseases in the maxillo-facial region in children occupy a leading place in the work of a polyclinic doctor. At the same time, their diagnosis is imperfect and they often occur on a premorbid background. The clinical features of acute odontogenic periostitis against the background of thyroid pathology in children were studied to improve the effectiveness of treatment. We examined 38 children, formed two groups of observations. Children of both groups were given generally accepted treatment. Children of the main group were additionally prescribed means "Imupret" and "Calcemin advance" to normalize the main protective indicators of oral fluid. Statistically assessed the degree of probability of the obtained results. The results of clinical observation of children showed the absence of pain on the 7th day of observation in both the children of the main group and the comparison group, indicating the pronounced anti-inflammatory and analgesic effects of drugs in complexes treatment. On the 7th day of treatment, clear hyperemia was not diagnosed in children of the follow-up groups, but patients with moderate oral mucosa hyperemia in the main group were in 2.22 times less than in the comparison ones (5.0% vs 11.11%, respectively). Minor swelling and exudation on the 7th day of observation were found only in children of the comparison group. Oral hygiene at the time of completion of treatment in all children was within satisfactory values. Analysis of the periodontal index of PMA showed the presence of catarrhal gingivitis in a third of children of both observation groups. Thus, the obtained results of clinical indicators of the state of the oral cavity of children indicate the effectiveness of our proposed method of treatment of acute purulent periostitis in children, which is confirmed by the stabilization of microvascular circulation, namely a decrease in the phenomena of edema and exudation. Due to local immunocorrective action, wound healing conditions are also improved and postoperative complications are prevented.

Keywords: acute odontogenic periostitis, children, thyroid disease, Imupret, Calcemin advance.
The Financial Impact of the COVID-19 Pandemic on Public Transportation and Sustainable Policy Recommendations: A Case Study of Eskişehir
Authors: YILDIZHAN Fatih , BİLGİÇ Şafak
Published: April 2022

Financing of public transportation has been a challenge that needs to be concerned because ridership has decreased by up to 90% with the impact of COVID-19. This study presents sustainable policy recommendations and their cost-benefit analyses for the financing problems in public transportation caused by COVID-19. First of all, the public transportation data of Eskişehir-Turkey between the years 2018-2021 were investigated according to different public transportation modes, and financial losses were calculated for municipality. Secondly, within the scope of the study, six policies were recommended as follows: (i) different network and service plans for public transportation, (ii) new or improved low-budget public transportation, (iii) congestion pricing, (iv) bike, bike-sharing and e-scooter, (v) park and ride, (vi) pedestrianization. Crucial points in the implementation of policies and their possible financial impacts were investigated. According to the findings of the study, total ridership decreased 72.94 million in 2020 and 2021 compared to pre-COVID-19. In different modes, it was observed that the decrease buses ridership was higher than in trams. Municipality financial loss was calculated as $19.69-24.87 million. In the cost-benefit analysis results of recommended policies, net present value was calculated as 0.28-23.36 million $ according to different scenarios and sensitivity analyses. It has been foreseen that this is a very suitable period for the implementation of these policies, they could provide sustainable urban transportation and increase the quality of life as well as solving financial problems.