bluuebunny/crossref_metadata_2025 huggingface dataset:
Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
Authors: Eltom Abdalla , Zhong Gaoyan , Muhammad Ameen
Published: March 2019

In this review paper, the definition of the tissue engineering (TE) was comprehensively explored towards scaffold fabrication techniques and applications. Scaffold properties and features in TE, biological aspects, scaffold material composition, scaffold structural requirements, and old and current manufacturing technologies were reported and discussed. In almost all the reviewed reports, the TE definition denotes renewal, development, and repairs of damaged tissues caused by various factors such as disease, injury, or congenital disabilities. TE is multidisciplinary that combines biology, biochemistry, clinical medicine, and materials science whose application in cellular systems such as organ transplantation serves as a delivery vehicle for cells and drug. According to the previous literature and this review, the scaffold fabrication techniques can be classified into two main categories: conventional and modern techniques. These TE fabrication techniques are applied in the scaffold building which later on are used in tissue and organ structure. The benefits and drawbacks of each of the fabrication techniques have been described in conjunction with current areas of research devoted to deal with some of the challenges. To figure out, the highlighted aspects aimed to define the advancements and challenges that should be addressed in the scaffold design for tissue engineering. Additionally, this study provides an excellent review of original numerical approaches focused on mechanical characteristics that can be helpful in the scaffold design assessment in the analysis of scaffold parameters in tissue engineering.
MicroRNAs in the Progress of Diabetic Nephropathy: A Systematic Review and Meta-Analysis
Authors: Wang Li-ping , Gao Yu-zhen , Song Bin , Yu Guo , Chen Hui , Zhang Zhen-wen , Yan Cai-feng , Pan Yun-long , Yu Xiao-yan
Published: March 2019

Background. We conducted a systematic review and meta-analysis of existing literature to evaluate the different outcomes of microRNAs (miRNAs) in diabetic nephropathy (DN), including urinary albumin excretion rates, urinary albumin creatinine rates, glomerular filtration rate, HbAc1, and creatinine.Methods. Electronic databases including PUBMED, MEDLINE, and EMBASE were searched for eligible publications to July 2018. The following comparisons between treatment groups were included: normal group versus DN group; control group versus micro/macroalbuminuria group.Results. Twelve eligible studies that included 2500 participants were finally recruited in this meta-analysis. Fifteen miRNAs (miRNA-21, miRNA-181b, miRNA-194, miRNA-30, miRNA-215, and others) were upregulated whereas seven miRNAs (miRNA-26a, miRNA-126, miRNA-424, miRNA-574-3p, miR-223, miR-155, and miR-192) were downregulated in the DN group compared with control groups. The miR-133b, miR-342, miR-30, miR-192, miR-194, and miR-215 were significantly correlated in urinary albumin excretion rates (r=0.33, 95% CI= 0.26-0.39). miR-192, miR-217, miR-15b, miR-34a, and miR-636 were correlated with urinary albumin creatinine rates (r=0.69; 95% CI=0.12-0.92), while miR-133b, miR-345, miR-33, miR-326, miR-574-3p, miR-126, miR-217, miR-15b, miR-34a, and miR-636 were significantly correlated with HbAc1 (r =0.23, 95% CI = 0.15-0.31). There were twelve miRNAs that were closely related to the glomerular filtration rate (r=0.28, 95% CI =0.21-0.34). Creatinine (r=0.33, 95% CI = 0.22-0.40) was significantly different between normal and DN groups.Conclusions. The meta-analysis acquired the correlations between miRNAs and outcomes including UAER, UACR, eGFR, HbAc1, and creatinine in DN. It suggested that miRNAs may participate in the pathogenesis of DN process.
Mixed Simultaneous Iterative Algorithms for the Extended Multiple‐Set Split Equality Common Fixed‐Point Problem with Lipschitz Quasi‐Pseudocontractive Operators
Authors: Li Meixia , Zhou Xueling , Che Haitao
Published: March 2019

In this paper, we study a kind of extended multiple‐set split equality common fixed‐point problem with Lipschitz quasi‐pseudocontractive operators, which is an extension of multiple‐set split equality common fixed‐point problem with quasi‐nonexpansive operator. We propose two mixed simultaneous iterative algorithms, in which the selecting of the stepsize does not need any priori information about the operator norms. Furthermore, we prove that the sequences generated by the mixed simultaneous iterative algorithms converge weakly to the solution of this problem. Some numerical results are shown to illustrate the feasibility and efficiency of the proposed algorithms.
Nerol Attenuates Ouabain-Induced Arrhythmias
Authors: Menezes-Filho José Evaldo Rodrigues de , Souza Diego Santos de , Santos-Miranda Artur , Cabral Valeska Moraes , Santos José Nilson Andrade , Cruz Jader dos Santos , Araujo Andreza Melo de , Vasconcelos Carla Maria Lins de
Published: March 2019

Nerol (C10H18O) is a monoterpene found in many essential oils, such as lemon balm and hop. In this study, we explored the contractile and electrophysiological properties of nerol and demonstrated its antiarrhythmic effects in guinea pig heart preparation. Nerol effects were evaluated on atrial and ventricular tissue contractility, electrocardiogram (ECG), voltage-dependent L-type Ca2+current (ICa,L), and ouabain-triggered arrhythmias. Overall our results revealed that by increasing concentrations of nerol (from 0.001 to 30 mM) there was a significant decrease in left atrium contractile force. This effect was completely and rapidly reversible after washing out (~ 2 min). Nerol (at 3 mM concentration) decreased the left atrium positive inotropic response evoked by adding up CaCl2in the extracellular medium. Interestingly, when using a lower concentration of nerol (30μM), it was not possible to clearly observe any significant ECG signal alterations but a small reduction of ventricular contractility was observed. In addition, 300μM nerol promoted a significant decrease on the cardiac rate and contractility. Important to note is the fact that in isolated cardiomyocytes, peak ICa,Lwas reduced by 58.9 ± 6.31% after perfusing 300μM nerol (n=7, p<0.05). Nerol, at 30 and 300μM, delayed the time of onset of ouabain-triggered arrhythmias and provoked a decrease in the diastolic tension induced by the presence of ouabain (50μM). Furthermore, nerol preincubation significantly attenuated arrhythmia severity index without changes in the positive inotropism elicited by ouabain exposure. Taken all together, we may be able to conclude that nerol primarily by reducing Ca2+influx through L-type Ca2+channel blockade lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
An Internal Limiting Membrane Plug and Gas Endotamponade for Recurrent or Persistent Macular Hole
Authors: Giansanti Fabrizio , Tartaro Ruggero , Caporossi Tomaso , Bacherini Daniela , Savastano Alfonso , Barca Francesco , Rizzo Stanislao
Published: March 2019

Introduction. Recurrent or persistent macular holes (MHs) are rare today due to the tendency to carefully peel the internal limiting membrane. Conversely, their treatment is still a challenge for a vitreoretinal surgeon. Materials and Methods. This is a retrospective, consecutive, and nonrandomized study of patients affected by recurrent or persistent MHs treated using small-gauge pars plana vitrectomy (25- or 23-gauge) and an autologous ILM plug, at the Eye Clinic of Azienda Ospedaliera Universitaria Careggi (Florence, Italy) between January 2016 and May 2018. We included 8 eyes of 8 patients in the study. Five patients had a recurrent MH while 3 had a persistent MH. The case series includes patients with myopic eyes and with large macular holes (>400 μ). Patients were followed up with ophthalmoscopic examinations and swept-source optical coherence tomography (SS-OCT). Results. The mean age of the patients was 74 years (±4.81 standard deviation (SD)), 3 patients were men and 5 women. The average axial length was 26.28 mm (±2.84 SD). Four patients had an AL ≧ 26 mm. The mean MH diameter was 436.5 (±49.82 SD). Average preoperative best-corrected visual acuity (BCVA) was 0.81 logMAR (±0.16 SD) and 20/125 Snellen. The ILM plug has been found integrated in the MH in all the follow-ups. Conclusion. In our study, an ILM autologous macular transplant was used successfully in 5 cases of macular hole recurrence and 3 cases of macular hole persistence. The anatomical success was achieved in all the cases; 4 patients improved their BCVA, and 4 patients maintained it. No macular alterations such as RPE or retinal atrophy/dystrophy were observed after 6 months.
New Bargaining Game Model for Collaborative Vehicular Network Services
Authors: Kim Sungwook
Published: March 2019

The wireless industry’s evolution from fourth generation (4G) to fifth generation (5G) will lead to extensive progress in new vehicular network environments, such as crowdsensing, cloud computing, and routing. Vehicular crowdsensing exploits the mobility of vehicles to provide location-based services, whereas vehicular cloud computing is a new hybrid technology that instantly uses vehicular network resources, such as computing, storage, and Internet for decision-making. In this study, novel crowdsensing, cloud computing, and routing algorithms are developed for a next-generation vehicular network, and they are combined into a hybrid scheme. To provide an effective solution toward an appropriate interactive vehicular network process, we focus on the paradigm of learning algorithms and game theory. Based on individual cooperation, our proposed scheme is designed as a triple-plane game model to adapt to the dynamics of a vehicular network system. The primary advantage of our game-based approach is to provide self-adaptability and responsiveness to current network environments. The performance of our hybrid scheme is evaluated and analyzed using simulation experiments in terms of the cloud service success ratio, normalized dissemination throughput, and crowdsensing success probability.
Antibacterial and Antibiotic Modifying Potential of Crude Extracts, Fractions, and Compounds from Acacia polyacantha Willd. against MDR Gram-Negative Bacteria
Authors: Mambe Flora T. , Na-Iya Jean , Fotso Ghislain W. , Ashu Fred , Ngameni Bathélémy , Ngadjui Bonaventure T. , Beng Veronique P. , Kuete Victor
Published: March 2019

The present study aimed to assess the in vitro antibacterial and antibiotic modifying activities of methanol extracts prepared from the leaf (APL) and bark (APB) of Acacia polyacantha, fractions (APLa-d) and compounds isolated from APL against a panel of multidrug resistant (MDR) Gram-negative bacteria. Leaf extract was subjected to column chromatography for compounds isolation; antibacterial assays were performed on samples alone and with an efflux pump inhibitor (EPI), respectively, and several antibiotics on the tested bacteria. The phytochemical investigation of APL led to the isolation of stigmasterol (1), β-amyrin (2), 3-O-β-D-glucopyranosylstigmasterol (3), 3-O-methyl-D-chiro-inositol (4), epicatechin (5), quercetin-3-O-glucoside (6), 3-O-[β-D-xylopyranosyl-(1→4)-β-D-galactopyranosyl]-oleanolic acid (7), and 3-O-[β-galactopyranosyl-(1→4)-β-D-galactopyranosyl]-oleanolic acid (8). APL and APB had minimal inhibitory concentration (MIC) values ≤ 1024 μg/mL on 73.3% and 46.7% of the tested bacteria, respectively. APLb and APLd were effective against 88.9% of tested bacterial species with compound 8 showing the highest activity inhibiting 88.9% of tested bacteria. The EPI, phenylalanine-arginine-β-naphthylamide (PAßN), strongly improved the activity of APL, APLb, APLd, and compound 8 on all tested bacteria. Synergistic effects were obtained when APL and compounds 7 and 8 were combined with erythromycin (ERY), gentamycin (GEN), ciprofloxacin (CIP), and norfloxacin (NOR). The present study demonstrates the antibacterial potential of Acacia polyacantha and its constituents to combat bacterial infections alone or in combination with EPI.
Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer
Authors: Vantaku Venkatrao , Dong Jianrong , Ambati Chandrashekar R. , Perera Dimuthu , Donepudi Sri Ramya , Amara Chandra Sekhar , Putluri Vasanta , Ravi Shiva Shankar , Robertson Matthew J. , Piyarathna Danthasinghe Waduge Badrajee , Villanueva Mariana , von Rundstedt Friedrich-Carl , Karanam Balasubramanyam , Ballester Leomar Y. , Terris Martha K. , Bollag Roni J. , Lerner Seth P. , Apolo Andrea B. , Villanueva Hugo , Lee MinJae , Sikora Andrew G. , Lotan Yair , Sreekumar Arun , Coarfa Cristian , Putluri Nagireddy
Published: March 2019

Purpose:

The perturbation of metabolic pathways in high-grade bladder cancer has not been investigated. We aimed to identify a metabolic signature in high-grade bladder cancer by integrating unbiased metabolomics, lipidomics, and transcriptomics to predict patient survival and to discover novel therapeutic targets.

Experimental Design:

We performed high-resolution liquid chromatography mass spectrometry (LC-MS) and bioinformatic analysis to determine the global metabolome and lipidome in high-grade bladder cancer. We further investigated the effects of impaired metabolic pathways using in vitro and in vivo models.

Results:

We identified 519 differential metabolites and 19 lipids that were differentially expressed between low-grade and high-grade bladder cancer using the NIST MS metabolomics compendium and lipidblast MS/MS libraries, respectively. Pathway analysis revealed a unique set of biochemical pathways that are highly deregulated in high-grade bladder cancer. Integromics analysis identified a molecular gene signature associated with poor patient survival in bladder cancer. Low expression of CPT1B in high-grade tumors was associated with low FAO and low acyl carnitine levels in high-grade bladder cancer, which were confirmed using tissue microarrays. Ectopic expression of the CPT1B in high-grade bladder cancer cells led to reduced EMT in in vitro, and reduced cell proliferation, EMT, and metastasis in vivo.

Conclusions:

Our study demonstrates a novel approach for the integration of metabolomics, lipidomics, and transcriptomics data, and identifies a common gene signature associated with poor survival in patients with bladder cancer. Our data also suggest that impairment of FAO due to downregulation of CPT1B plays an important role in the progression toward high-grade bladder cancer and provide potential targets for therapeutic intervention.
Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy
Authors: Malavasi Fabio , Faini Angelo Corso
Published: March 2019

Antibody therapy is a treatment option for several diseases, including multiple myeloma. The logic behind it is relatively simple: A target molecule is selected because of its expression on tumor cells, and the antibody delivers cytotoxic effects. Therapeutic results in multiple myeloma indicate that the anti-CD38 antibodies may have relevant immunotherapeutic properties.

See related article by Moreno et al., p. 3176
Multivessel Coronary Revascularization Strategies in Patients with Chronic Kidney Disease: A Meta-Analysis
Authors: Wu Panyun , Luo Fei , Fang Zhenfei
Published: March 2019

Background: Early revascularization can lead to better prognosis in multivessel coronary artery disease (CAD) patients with chronic kidney disease (CKD). However, whether coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) is better remains unknown. Methods: We searched PubMed and the Cochrane Library database from inception until December 9, 2017, for articles that compare outcomes of CABG and PCI in multivessel CAD patients with CKD. We pooled the odds ratios with a fixed-effects model when I2 < 50% or a random-effects model when I2 > 75% and conducted heterogeneity and quality assessments as well as publication bias analyses. Results: A total of 17 studies with 62,343 patients were included. Compared with CABG, the pooled analysis showed that PCI had a lower risk of short-term all-cause death (OR, 0.56; 95% CI, 0.37–0.84) and cerebrovascular accidents (OR, 0.65; 95% CI, 0.53–0.79) but a higher risk of cardiac death (OR, 1.29; 95% CI, 1.21–1.37), myocardial infarction (MI) (OR, 1.73; 95% CI, 1.35–2.21), and repeat revascularization (RR) (OR, 3.9; 95% CI, 2.99–5.09). There was no significant difference in the risk of long-term all-cause death (OR, 1.08; 95% CI, 0.95–1.23) and major adverse cardiac and cerebrovascular events (MACCE) (OR, 1.58; 95% CI, 0.99–2.52) between the PCI and CABG groups. A subgroup analysis restricted to patients treated with dialysis or with PCI-drug-eluting stent yielded similar results. Conclusions: PCI for patients with CKD and multivessel disease (multivessel CAD) had advantages over CABG with regard to short-term all-cause death and cerebrovascular accidents, but disadvantages regarding the risk of myocardial death, MI, and RR; there was no significant difference in the risk of long-term all-cause death and MACCE. Large randomized controlled trials are needed to confirm our findings.
Use of Rifabutin as an Alternative Agent for Human Brucellosis: A Case Report
Authors: Karabay Oguz , Okan Huseyin Dogus , Simsek Adem , Guclu Ertugrul
Published: March 2019

Drugs that have a good intracellular passage are used in the treatment of brucellosis. According to our knowledge, there is no report in English about rifabutin usage in brucellosis. We present a case that developed intolerance to many anti-brucella drugs, who was then successfully treated with a combination of rifabutin, ofloxacin, and ceftriaxone.
A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume
Authors: Molitoris Bruce A. , George Anthony G. , Murray Patrick T. , Meier Daniel , Reilly Erinn S. , Barreto Erin , Sandoval Ruben M. , Rizk Dana V. , Shaw Andrew D. , Peacock W. Frank
Published: March 2019

Objectives: To determine the performance of a rapid fluorescent indicator technique for measuring plasma volume (PV). Methods: This was an open-label, observational evaluation of a two-component intravenous visible fluorescent dye technique to rapidly measure PV in 16 healthy subjects and 16 subjects with chronic kidney disease (8 stage 3 and 8 stage 4 CKD), at 2 clinical research sites. The method consisted of a single intravenous injection of 12 mg of a large 150-kDa carboxy-methyl dextran conjugated to a fluorescent rhodamine-derived dye as the PV marker (PVM), and 35 mg of a small 5-kDa carboxy-methyl dextran conjugated to fluorescein, the renal clearance marker. Dye concentrations were quantified 15 min after the injections for initial PV measurements using the indicator-dilution principle. Additional samples were taken over 8 h to evaluate the stability of the PVM as a determinant of PV. Blood volumes (BV) were calculated based on PV and the subject’s hematocrit. Pharmacokinetic parameters were calculated from the plasma concentration data taken over several days using noncompartmental methods (Phoenix WinNonlin®). Linear correlation and Bland-Altman plots were used to compare visible fluorescent injectate-measured PV compared to Nadler’s formula for estimating PV. Finally, 8 healthy subjects received 350 mL infusion of a 5% albumin solution in normal saline over 30 min and a repeat PV determination was then carried out. Results: PV and BV varied according to weight and body surface area, with PV ranging from 2,115 to 6,234 mL and 28.6 to 41.9 mL/kg when weight adjusted. Both parameters were stable for > 6 h with repeated plasma measurements of the PVM. There was no difference between healthy subjects and CKD subjects. Overall, there was general agreement with Nadler’s estimation formula for the mean PV in subjects. A 24-h repeat dose measurement in 8 healthy subjects showed PV variability of 98 ± 121 mL (mean = 3.8%). Additionally, following an intravenous bolus of 350 mL of a 5% albumin solution in normal saline in 8 healthy subjects, the mean (SD) measured increase in PV was 356 (±50.0) mL post-infusion. There were no serious adverse events reported during the study. Conclusions: This minimally invasive fluorescent dye approach safely allowed for rapid, accurate, and reproducible determination of PV, BV, and dynamic monitoring of changes following fluid administration.
Proteomics Profiling and Risk of New‐Onset Atrial Fibrillation: Framingham Heart Study
Authors: Ko Darae , Benson Mark D. , Ngo Debby , Yang Qiong , Larson Martin G. , Wang Thomas J. , Trinquart Ludovic , McManus David D. , Lubitz Steven A. , Ellinor Patrick T. , Vasan Ramachandran S. , Gerszten Robert E. , Benjamin Emelia J. , Lin Honghuang
Published: March 2019

Background

Prior studies relating proteomics markers to incident AF screened for limited numbers of proteins.

Methods and Results

We performed proteomics assays among participants from the Framingham Heart Study Offspring attending their fifth examination. Plasma protein levels (n=1373) were measured by the SOMAscan proteomic profiling platform. We used robust inference for the Cox proportional hazards model to relate each protein level with incident AF. In addition, we examined the association between AF‐related genetic loci and levels of proteins associated with AF. Our study included 1885 participants (mean age 55±10 years, 54% women) who had proteomic profiles measured. A total of 349 participants developed AF during follow‐up (mean follow‐up 18.3 years). We observed that 8 proteins were significantly associated with incident AF after adjusting for age, sex, technical covariates, and correction for multiple testing (
P
<0.05/1373=3.6×10
−5
). After additional adjustments for clinical factors associated with AF, ADAMTS13 and N‐terminal pro‐B‐type natriuretic peptide remained significantly associated with the risk of incident AF (hazard ratio, 0.78; 95% CI, 0.70–0.88; and 1.44; 95% CI, 1.22–1.70, respectively;
P
<3.6×10
−5
for both). None of the 8 proteins were encoded by genes at AF‐related genetic loci previously identified by genome‐wide association studies.

Conclusions

We identified 8 proteins associated with risk of incident AF after adjustment for age and sex; 2 proteins were associated with AF after adjustment for AF risk factors. Future studies are needed to replicate our findings, identify whether the markers are mechanistically related to AF development, and whether they are clinically useful for identification of future AF risk.
Ambient Coarse Particulate Matter and Hospital Admissions for Ischemic Stroke
Authors: Tian Yaohua , Liu Hui , Xiang Xiao , Zhao Zuolin , Juan Juan , Li Man , Song Jing , Cao Yaying , Wu Yao , Wang Xiaowen , Chen Libo , Wei Chen , Gao Pei , Hu Yonghua
Published: March 2019

Background and Purpose—

Evidence on the effects of coarse particulate matter (PM
10–2.5
) on ischemic stroke is limited and inconsistent. We evaluated the acute effects of PM
10–2.5
exposure on hospital admissions for ischemic stroke in China.

Methods—

We conducted a national time-series analysis of associations between daily PM
10–2.5
concentrations and daily hospital admissions for ischemic stroke in China between January 2014 and December 2016. Hospital admissions for ischemic stroke were identified from the database of Urban Employee Basic Medical Insurance, which contains data from 0.28 billion beneficiaries. We applied a city-specific Poisson regression to examine the associations of PM
10–2.5
and daily ischemic stroke admissions. We combined the city-specific effect estimates with a random effects meta-analysis, and further evaluated the exposure-response relationship curve and potential effect modifiers.

Results—

We identified >2 million hospital admissions for ischemic stroke in 172 Chinese cities. A 10 μg/m
3
increase in PM
10–2.5
concentrations (lag day 0) was associated with a 0.91% (95% CI, 0.73–1.10) increase in hospital admissions for ischemic stroke. The association remained significant after adjusting for PM
2.5
(percentage change, 0.96%; 95% CI, 0.75–1.18). The exposure-response relationship was approximately linear, with a moderate response at lower levels (<200 μg/m
3
) and a steeper response at higher levels. The association was stronger in cities with lower PM
10–2.5
concentrations, higher temperatures, or higher relative humidity.

Conclusions—

This nationwide study provides robust evidence of the short-term association between exposure to PM
10–2.5
and increased hospital admissions for ischemic stroke and supports the hypothesis that the association differs by city characteristics.
A new species of Rhododendron (Ericaceae) from northeastern Yunnan, China
Authors: TIAN XIAO-LING , CHANG YU-HANG , NEILSEN JENS , WANG SI-HAI , MA YONG-PENG
Published: March 2019

The genus Rhododendron Linnaeus (1753: 392) has more than 1,000 species that have been recognized in the temperate areas of the world (Chamberlain et al. 1996). In China, ca. 600 species of Rhododendron have been confirmed, including numerous species described after the publishing of Flora of China (Chen et al. 2010, Chen et al. 2012, Ma et al. 2013, Liao et al. 2015, Ma et al. 2015, Cai et al. 2016). They occur in most of China’s provinces except Xinjiang and Ningxia (Ma et al. 2014). Among these provinces, Yunnan, Sichuan and Tibet have the greatest diversity.
Description and behaviour of Goniotropis kuntzeni larvae (Coleoptera: Carabidae: Paussinae: Ozaenini) and a key to genera of Paussinae larvae
Authors: MOORE WENDY , GIULIO ANDREA DI
Published: March 2019

Goniotropis species are large, parallel-sided paussine beetles common in the New World tropics and ranging from southern Arizona to northern Argentina.  Specimens of Goniotropis kuntzeni Bänninger were collected in southern Arizona and larvae were reared under laboratory conditions.  The egg, first instar larva and second instar larva are described and illustrated, providing the first larval description for this genus.  Goniotropis larvae live in burrows that they construct and seal with their terminal disk (which is composed of modified urogomphi and dorsal plates).  They feed by trapping live insect prey with the moveable components of their terminal disk, and then they bring the captured prey into their gallery to consume.  Burrowing and feeding behaviours of Goniotropis kuntzeni larva closely resemble those previously described for Pachyteles species.  A key to the genera of paussine larvae is provided.
Revision of Southern Hemisphere Austronanus Hodgson, 1910, with two new genera and five new species of Paramunnidae (Crustacea: Isopoda: Asellota)
Authors: JUST JEAN , WILSON GEORGE D.F.
Published: March 2019

Paramunnid species of Southern Hemisphere cold-water Austronanus Hodgson, 1910 and related genera are characterised by simple, smooth, flattened, rather elongate oval bodies, a broadly projecting frontal head margin, well-developed, short, mostly distally bulging eyestalks with ommatidia, pereonites with lateral margins contiguous, rounded or truncate, and dorsally visible coxae V–VII. Just and Wilson (2004) rejected synonymy of Austronanus with Paramunna Sars proposed by Nordenstam (1933), following a revision of the latter genus. The type species, Austronanus glacialis Hodgson, 1910, is re-described based on topotypic material from McMurdo Sound, Antarctica, (the holotype is a small manca). The types of Paramunna dentata Nordenstam, 1933 and P. dubia Hale, 1937 are re-described and the two species referred to Austronanus together with three new Antarctic and subantarctic species, A. aucklandensis, A. gelidus and A. mawsoni. Paramunna patagoniensis Winkler, 1994 is redescribed and made the type species of a new genus, Xigonus. A new genus, Stephenseniellus, is established for two new species from the subantarctic islands south of New Zealand and Australia, S. palliolatipes (type species) from Macquarie Island, and S. serraticornis (originally reported by Stephensen, 1927 as “Paramunna (serrata (Richardson) ?”) from Auckland Island.
Natarsia Fittkau (Diptera: Chironomidae: Tanypodinae) from China
Authors: CHENG MING , WANG XINHUA H.
Published: March 2019

The chironomid genus Natarsia is recorded from the Oriental Region for the first time. Natarsia nugax (Walker) is redescribed and Natarsia qinlingica sp. n. is described from males. A key to adult males is presented and the generic description is emended.
The first five years of Zootaxa
Authors: ZHANG ZHI-QIANG
Published: March 2019

Zootaxa was founded in 2001 as a new print and online journal of systematic zoology.   It was designed to help systematic zoologists to rapidly document and analyze world’s zoological diversity, which includes many undescribed species now threatened by the rapid loss of habitats. Overcoming the ‘taxonomic impediment’ by helping taxonomists to rapidly document world’s undescribed animals is Zootaxa’s main mission.
Evidence of full species status of the neotropical leaf-frog Phyllomedusa burmeisteri bahiana (A. Lutz, 1925) (Amphibia, Anura, Hylidae)
Authors: SILVA-FILHO IVAN S.N. , JUNCÁ FLORA A.
Published: March 2019

The full species status of Phyllomedusa burmeisteri bahiana was investigated based on tadpoles and vocalizations characteristics. We found distinct characteristics between the tadpoles and advertisement and territorial calls of the former and that of Phyllomedusa burmeisteri burmeisteri. The main tadpole differences are related with a skin projection protecting the spiracle, origin of dorsal fin, morphology of ventral fin and distribution of papillae on the oral disc. The advertisement call and territorial call of Phyllomedusa b. bahiana were different from the P. b. burmeisteri calls especially for the structure and temporal characteristics (pulses/second principally). The color of newly metamorphosed Phyllomedusa b. bahiana suggests that the color pattern of the internal sides of the thigh of P. b. burmeisteri can be related to a neotenic pattern of development. We elevate Phyllomedusa b. bahiana to species level based on morphological and acoustical traits decribed here.
Phytoseiid mites of the subtribes Typhlodromalina and Euseiina (Acari: Phytoseiidae: Euseiini) from sub-Saharan Africa
Authors: DE MORAES G. J. , ZANNOU I. D. , OLIVEIRA A. R. , YANINEK J. S. , HANNA R.
Published: March 2019

Twenty-four phytoseiid species of the subtribe Typhlodromalina Chant & McMurtry are reported in this paper. They refer to all species of this subtribe now known to occur in sub-Saharan Africa, and they belong to the genera Amblydromalus Chant & McMurtry (5 species), Prasadromalus Chant & McMurtry (1 species), Typhlodromalus Muma (7 species) and Ueckermannseius Chant & McMurtry (11 species). Ten of these species are described for the first time and 11 species are redescribed. All of these were collected in cassava habitat, in an effort to determine the mites of that agro-ecosystem in that region. Redescriptions are based mostly on specimens collected in this study; for 6 species, redescriptions are also based on type specimens. A key to help in the separation of Typhlodromalina presently known to occur in sub-Saharan Africa is included. The morphological relation between a group of sub-Saharan species of Euseius (2 of which first described in this paper) and Ueckermannseius is also discussed.
First record of Syntormon from Singapore with the description of a new species (Insecta, Diptera, Dolichopodidae)
Authors: GROOTAERT PATRICK , YANG DING , WANG MENGQING
Published: March 2019

The genus Syntormon is recorded for the first time from Singapore. Syntormon singaporensis sp. nov. is described and illustrated.
Three species of the isopod crustacean genus Antennuloniscus Menzies, 1962 (Asellota: Haploniscidae) from the Southern Ocean
Authors: BRÖKELAND WIEBKE
Published: March 2019

The genus Antennuloniscus is rediagnosed and discussed. Antennuloniscus ornatus Menzies, 1962 and A. armatus Menzies, 1962 are redescribed and A. latoperculus n. sp. is described from material obtained from the Southern Ocean.
New species of Pygolabis Wilson, 2003 (Isopoda, Tainisopidae, Crustacea) from Western Australia
Authors: KEABLE STEPHEN J. , WILSON GEORGE D. F.
Published: March 2019

Four new isopod species of the hypogean genus Pygolabis (family Tainisopidae) are described from the Pilbara and Gascoyne regions of Western Australia. The species appear to be restricted to small areas in the ground waters below single or neighbouring creek beds. These species are similar in overall morphology, and are primarily identified using features of the pleotelson, uropods and the shape of the appendix masculina on the male pleopod 2.
Cordylancistrus nephelion (Siluriformes, Loricariidae), a new and endangered species of suckermouth armored catfish from the Tuy River, north-central Venezuela
Authors: PROVENZANO FRANCISCO , MILANI NADIA
Published: March 2019

A new species of suckermouth armored catfish, Cordylancistrus nephelion, is described from seven specimens collected in tributaries of the Tuy River in the Caribbean Sea basin of north-central Venezuela. Cordylancistrus nephelion can be distinguished from the other species assigned to its genus by its unique color pattern, the head and body being marked with irregular white spots. Cordylancistrus nephelion is the third species of the genus described from Venezuela: Cordylancistrus torbesensis (Schultz 1944) from the Mérida mountain range (Cordillera de Mérida), Orinoco River basin; C. perijae Pérez and Provenzano 1996 from Perijá mountain range (Sierra de Perijá), Maracaibo Lake basin; and now C. nephelion from the La Costa mountain range (Cordillera de La Costa). These three species inhabit isolated foothill rivers and have very restricted geographic distributions. The extreme alteration of the Tuy River basin by humans may threaten Cordylancistrus nephelion and the other fish species endemic to the basin with extinction. An artificial key for the species assigned to the genus Cordylancistrus is presented.
Three new species of Gastromyzon (Teleostei: Balitoridae) from the Temburong River basin, Brunei Darussalam, Borneo
Authors: TAN H. H. , SULAIMAN Z. H.
Published: March 2019

Three new species of Gastromyzon from Brunei Darussalam, on the island of Borneo, are described from recent collections and from older museum specimens. Gastromyzon cranbrooki, new species, is superficially similar to G. borneensis, but differs in having a distinct secondary rostrum; body brown with 9–10 grey bars, head dorsum dark brown with thin grey reticulate pattern; and 56–60 scales on lateral line. Gastromyzon aeroides, new species, is similar to G. punctulatus, but differs in having the body uniform brown, dorsum uniform brown; head dorsum with very fine cream reticulate pattern (similar to a cream head with brown spots and blotches); dorsal, caudal and anal fins blue in life; and 47–65 scales in lateral line. Gastromyzon venustus, new species, is similar to G. pariclavis, but differs in having both the body and head dorsum plain brown; dorsal, caudal and anal fins red in life; and 58–63 scales in lateral line.
New species of Loandalia (Polychaeta: Pilargidae) from Queensland, Australia
Authors: MARKS SHONA , HOCKNULL SCOTT
Published: March 2019

Two new species of Loandalia are described from Queensland, Australia. Loandalia fredrayorum sp. nov. is described from Moreton Bay, south eastern Queensland and is distinguished from all other species of Loandalia by the presence of singular palpostyles; uniramous parapodia at chaetiger 1; an emergent notopodial spine at chaetiger 9; neurochaetae numbering 20–24; ventral cirri begin on chaetiger 7 and the pygidium with two lateral papillae-like anal cirri. Loandalia gladstonensis sp. nov. is described from Gladstone Harbour, central eastern Queensland and is distinguished from all other species of Loandalia by the presence of bifid palpostyles; chaetiger 1 uniramous with remaining chaetigers biramous; an emergent notopodial spine from chaetiger 7–8; ventral cirri present from chaetiger 5 and neurochaetae numbering 5–6.
Heterochrony in Haplomesus (Crustacea: Isopoda: Ischnomesidae): revision of two species and description of two new species
Authors: KAVANAGH FIONA A. , WILSON GEORGE D.F. , POWER ANNE M.
Published: March 2019

Two new species of Ischnomesidae, Haplomesus celticensis sp. nov. and Haplomesus hanseni sp. nov. are described from the southwest of Ireland and the Argentine Basin respectively. Both species lack the expression of pereopod VII, a characteristic that we argue is produced by progenesis, not neoteny as suggested by Brökeland & Brandt (2004). Haplomesus angustus Hansen, 1916 and Haplomesus tropicalis Menzies, 1962, also lack pereopod VII and are revised from the type material. The original description of Haplomesus angustus Hansen, 1916 describes the adult type specimen as a juvenile; the original description of Haplomesus tropicalis Menzies, 1962 fails to mention the lack of pereopod VII. Progenesis is discussed for the above species and within the family Ischnomesidae as a whole.
A new species and new record of Rhombognathus from Singapore (Acari: Halacaridae)
Authors: BARTSCH ILSE
Published: March 2019

A new species, Rhombognathus aspidotus, and a new record, Rhombognathus scutulatus Bartsch, are reported from the shores of Singapore. The new species is characterized by the presence of a dorsal shield and is similar to R. scutulatus. The shape of the claws and the ornamentation of the dorsal shield separate R. aspidotus from R. scutulatus.
Engaging International Publics via Mobile-Enhanced CSR (mCSR): A Cross-National Study on Stakeholder Reactions to Corporate Disaster Relief Efforts
Authors: Chen Yi-Ru Regina , Cheng Yang , Hung-Baesecke Chun-Ju Flora , Jin Yan
Published: March 2019

With globalization, corporations increasingly have to consider both domestic stakeholders and overseas stakeholders (i.e., international publics) in their corporate social responsibility (CSR) practice. Digitalization empowers international publics to scrutinize and react to a (multinational) corporation’s CSR strategy, further affecting corporate outcomes of CSR practice. Drawing on the social media context and attribution theory, this study investigated international publics’ reactions to corporate disaster relief, an emerging type of mobile-enhanced CSR (i.e., mCSR) practice, in the United States and China by looking at individuals’ engagement with mobile social media during disasters, attribution of CSR motives, and level of CSR skepticism. Using structural equation modeling analysis, the survey data of randomly recruited Americans ( n = 816) and mainland Chinese ( n = 430) suggested that mobile social media engagement reinforces the values-, strategic-, and stakeholder-driven motives of mCSR in the United States and China. Egoistic-driven CSR motives elicited publics’ skepticism toward mCSR, while values- and stakeholder-driven motives inhibited skepticism in both countries. However, the effect of strategic-driven motives on skepticism was inconsistent internationally. Last, CSR skepticism triggered negative relational outcomes between the mCSR-performing corporation and various stakeholders in both countries. This study advances CSR and attribution theory and contributes to the practice of CSR, public relations, and international business in the social media and disaster response context.
Circuits, the everyday and international relations: Connecting the home to the international and transnational
Authors: Mac Ginty Roger
Published: March 2019

The primary aim of this article is methodological. It proposes circuitry as an analytical device – not a mere metaphor – as a way of connecting the everyday and the hyper-local to the national, international, transnational and all levels in between. Thus, the article is concerned with international relations’ perennial levels of analysis problem. The study is prompted by empirical research from the Everyday Peace Indicators project in which research subjects narrated their own (in)security in terms of the home and the immediate vicinity of the home. The home can be regarded as a key part of everyday and ontological security for many people, but how do we connect this to the international and transnational? The article draws on the literature on engineered and biological circuits in order to propose a novel analytical device with which to emphasise the connectivity between apparently unconnected levels. A life history is used to illustrate how the analytical device might be operationalised.
The Impact of Business Improvement District Proximity on Street Block Robbery Counts
Authors: Clutter Jeffrey E. , Henderson Samantha , Haberman Cory P.
Published: March 2019

This study examined the impact of business improvement districts (BIDs) on street block robbery counts in Cincinnati, OH. The relationships among BIDs (as well as other relevant control measures) and street block robbery counts were then examined using negative binomial regression models. Results showed that BIDs played an important role in the spatial patterning of robbery at the street block level. Street blocks within BIDs experienced higher street robbery counts even after controlling for street network betweenness and the presence of potentially criminogenic places within and around BIDs. Although previous research suggests BID implementation leads to crime reductions, the present study shows BIDs still provide ample opportunities for criminal activity as one component of the environmental backcloth.
Discovering the Saga of Inter-caste Marriage in India
Authors: Narzary Pralip Kumar , Ladusingh Laishram
Published: March 2019

In India marrying across the caste kindles strong community resentment, leading to the extent of honor killing, yet few couples dare to defy this stringent social norm. Analysis of large-scale survey (India Human Development Survey 2011–12) data exhibits an inconsequential rise in this social incongruity since 1951 to attain 4.5% in 2012. It is most prevalent in the northeastern region (11.6%), but least prevalent in caste-ridden central India (1.8%). Multi-variate statistics exhibit that if women are allowed to choose their life-partner, caste takes a rear-seat in marriage contemplation. It is quite prominent among the women who selected the husband by themselves and knew the husband at least one year before the marriage. Contrary to general notion, education is not able to promote inter-caste marriage. Odds of inter-caste marriage taking place in Dalit (lowest social standing) households is much lesser than the higher caste. Resilient targeted efforts are necessary to promote inter-caste marriage, which may loosen the noose of the caste system in India.
Mental Health Services in Childhood: The Role of Family Adversity
Authors: Alcalá Héctor E. , Balkrishnan Rajesh
Published: March 2019

Objective:

Much of the research on the effects of childhood adversity on mental health has focused on adults. The objective of our study was to examine the individual and cumulative effect of childhood adversity on mental health service use among children.

Methods:

We used data from the 2011-2012 National Survey of Children’s Health (n = 79 834) to determine the use of mental health services in the past 12 months among children aged 2-17. The independent variables of interest were experiencing any 1 of 9 adverse family experiences (AFEs). We used logistic regression models to determine if each AFE was associated with mental health service use. We also examined AFEs as a continuous measure, representing the number of AFEs (ranging from 0 to 9) that summed them individually, and we examined age-by-AFE and age-by-need interaction terms. We adjusted all models for confounders.

Results:

Compared with not experiencing an AFE, experiencing all AFEs was associated with higher odds of mental health service use. Neighborhood violence was associated with the greatest increase in odds of mental health service use (adjusted odds ratio [aOR] = 2.35; 95% confidence interval [CI], 2.00-2.77). When measured as a continuous scale, each additional AFE was associated with higher odds of mental health service use (aOR = 1.33; 95% CI, 1.28-1.37). The effect of AFEs on mental health service use decreased with age.

Conclusions:

The observed association between AFEs and use of mental health services may be attributable to more severe or poorly managed mental illness among these children. Efforts are needed to increase access to and quality of mental health care among children affected by AFEs.
The importance of having fun: Daily play among adults with type 1 diabetes
Authors: Van Vleet Meredith , Helgeson Vicki S. , Berg Cynthia A.
Published: March 2019

Although play has been linked to psychological and physical well-being in childhood, little work has examined benefits of play in adulthood. Play may be especially important in the context of coping with a chronic illness such as type 1 diabetes as self-care involves a difficult daily process. We hypothesized that daily play with one’s romantic partner would be linked to better mood, greater diabetes disclosure, greater support receipt, greater perceived coping effectiveness with one’s most important daily stressors, and better self-care regarding type 1 diabetes. We examined these hypotheses in a sample of 199 adults with type 1 diabetes. Participants completed daily diary measures of play with their partner and proposed outcomes for 14 days. Daily play was linked to better mood, greater diabetes disclosure to one’s partner, greater support received from one’s partner, and greater perceived coping effectiveness with the day’s most important diabetes and general stressors. However, daily play was unrelated to self-care. Mediation analyses further indicated that positive mood explained links from daily play to perceived coping effectiveness, and diabetes disclosure explained links from daily play to support. These findings indicate that having fun with one’s partner may have important psychological and relationship benefits for individuals with chronic illness. More work needs to be conducted to examine links from daily play to self-care. Implications are discussed.
I am a rock; I am an island: Implications of avoidant attachment for communal coping in adults with type 2 diabetes
Authors: Van Vleet Meredith , Helgeson Vicki S.
Published: March 2019

Accumulating evidence indicates that communal coping is beneficial for individuals with chronic illness. The current investigation examined attachment as a moderator of the effects of communal coping in a sample of persons with type 2 diabetes. We hypothesized that patient communal coping would be associated with higher relationship quality, lower distress, and better diabetes outcomes for patients low in avoidant attachment, but it would not be beneficial for patients high in avoidant attachment. Patient communal coping was coded from videotaped interactions in which 86 heterosexual couples discussed difficulties managing diabetes. The results indicated that patient communal coping was beneficial when avoidant attachment was low. When avoidant attachment was high, patient communal coping was related to lower relationship quality and higher distress and was unrelated to diabetes outcomes. This work sheds light on potential boundary conditions of communal coping’s benefits, which will be important to consider in future communal coping interventions.