bluuebunny/crossref_metadata_2025 huggingface dataset:
Perbandingan kemoterapi dan kombinasi imuno-kemoterapi sebagai terapi neoajuvan pada tatalaksana kasus Non Small Cell Lung Cancer (NSCLC): sebuah tinjauan pustaka
Authors: Karyadi I Gede Riswandinatha , Putra I Gusti Ngurah Agung Jaya Semara
Published: September 2024

NSCLC is a type of lung cancer with a poor prognosis and high mortality. Providing immunotherapy as neoadjuvant therapy in addition to chemotherapy in NSCLC cases has shown benefits in improving patient prognosis. This literature review will discuss further the comparison of chemotherapy and combination immuno-chemotherapy as neoadjuvant therapy in the management of NSCLC cases.
Immunotherapy using immune checkpoint inhibitors (ICI) increases antitumor immunity by inhibiting signaling at checkpoint receptors expressed by T lymphocytes and ligands on tumor cells, which has revolutionized the therapy of several cancers, including NSCLC. Neoadjuvant therapy in the form of a combination of immuno-chemotherapy has superior clinical benefits compared to the use of chemotherapy alone as neoadjuvant therapy as evidenced by better overall survival (OS) and event-free survival (EFS), pathological remission in the form of better MPR and CPR, and higher resection rates without increasing the presence of treatment-related adverse events and post-surgical complications.
Combination immunochemotherapy is superior to chemotherapy alone as neoadjuvant therapy in treating NSCLC.
 
NSCLC merupakan jenis kanker paru dengan prognosis yang cenderung buruk dan mortalitas tinggi. Pemberian imunoterapi sebagai terapi neoadjuvan selain kemoterapi pada kasus NSCLC menunjukkan manfaat membaiknya prognosis pasien. Tinjauan pustaka ini akan membahas lebih lanjut mengenai perbandingan kemoterapi dan kombinasi imuno-kemoterapi sebagai terapi neoadjuvan pada tatalaksana kasus NSCLC.
Imunoterapi dengan menggunakan inhibitor cekpoint imun atau immune checkpoint inhibitors (ICI) bekerja dengan meningkatkan imunitas antitumor melalui penghambatan pensinyalan pada reseptor cekpoint yang diekspresikan oleh limfosit T dan ligan pada sel tumor telah merevolusi terapi sejumlah kanker, termasuk NSCLC. Terapi neoadjuvan berupa kombinasi imuno-kemoterapi memiliki manfaat klinis yang lebih superior dibandingkan penggunaan kemoterapi tunggal sebagai terapi neoadjuvan dibuktikan dengan angka kesintasan keseluruhan (OS) dan event free survival (EFS) yang lebih baik, remisi patologis berupa MPR dan CPR yang lebih baik, dan tingkat reseksi yang lebih tinggi tanpa meningkatkan adanya efek samping yang berkaitan dengan terapi (treatment related adverse event) dan komplikasi pasca pembedahan.
Kombinasi imunokemoterapi lebih superior dibandingkan kemoterapi tunggal sebagai terapi neoadjuvan dalam tatalaksana NSCLC.
Early diagnosis and treatment of Kawasaki Disease: A case report
Authors: Jonathan Jason , Ali Muhammad , Wibisono Johannus S.
Published: September 2024

Introduction: Kawasaki Disease is an acute febrile illness primarily affecting children under the age of five. Kawasaki Disease presents challenges in diagnosis and management due to its diverse clinical manifestations and potentially serious complications. Hence, this case report highlights the importance of early diagnosis and treatment of Kawasaki Disease towards the patient’s outcome.
Case Illustration: A 3 year 9-month-old female infant visited the hospital with fever, a swollen left neck-cheek area, intermittent coughs and a sore throat. On the third day, the patient presents themselves once again with the fever and swollen neck not subsided, and redness on both eyes. The patient was then admitted into the hospital for observation of Incomplete Kawasaki Disease with initial treatment of IV Antipyretics and Antibiotics. On the fourth day, the patient began to experience rash on her extremities with a Harada score of 4/7. On the fifth day, no echocardiography could be done due to instrument availability but diagnosis stood with typical Kawasaki Disease from a clinical perspective. The patient was then started on acetylsalicylic acid and IVIG Immunoglobulin. The patient recovered well clinically over the next few days and an echocardiography was done 2 weeks post-treatment. The results showed that there were no signs of coronary aneurysms nor abnormal heart structures.
Conclusion: After early recognition and treatment of Kawasaki Disease, there was a swift clinical improvement and no detected complications. Kawasaki Disease should be considered following a fever of 5 days with clinical signs for prompt treatment to prevent complications.
The correlation between anemia and intelligence quotient (IQ) in children: a systematic review and meta-analysis
Authors: Janet Tee  , Paulus Ivana Beatrice , Suryawan I Wayan Bikin
Published: September 2024

Introduction: Anemia is considered as an important health problem because it severely affects children's growth and development. It impairs the immune mechanisms and is also associated with increased morbidity. This meta-analysis aims to assess the correlation between anemia and intelligence quotient (IQ) in children.
Methods: Articles on anemia and IQ in children under 18 years old were searched in Scopus, Pubmed, and ScienceDirect, using the search term “(((Anemia) OR (Hemoglobin)) AND ((Intelligence Quotient) OR (IQ)))”. Articles before 2000 and published in languages other than English were excluded. The outcome is Intelligence Quotient. Two independent reviewers performed article screening. The risk of bias was assessed using the Newcastle-Ottawa Scale (NOS). The statistical analysis was conducted using Review Manager 5.4.
Results: A total of 7 published studies with a total number of 1339 subjects were included in this meta-analysis. The pooled analysis showed there was a statistically significant decrease in mean IQ in anemic children, compared to non-anemic children (-9.97, 95% CI: -17.99 to -1.96, p = 0.01, I2 = 99%). All of the studies have a low risk of bias.
Conclusion: A decrease in mean IQ in children under 18 years old is associated with the presence of anemia.
Book announcements
Authors: Powell Richard
Published: September 2024

Announcements of five recently published volumes.
Real-time control action formation for predicting post-accident electrical modes considering permissible stability margins
Authors: Tokhtibakiev Karmel , Gunin Alexandr , Kenessov Yerlan , Vassilyev Daniil , Bektimirov Anur
Published: September 2024

The object of the research is an emergency control system for ensuring the stability of electric power systems (EPS) in case of emergency unbalances. The relevance of the problem of ensuring EPS stability is due to the need to improve the efficiency of emergency control to reduce the risk of system accidents with significant damage. To solve this problem, we propose an algorithm for selecting the volume of control actions based on the principles of adaptive control for predicting the post-emergency mode with an acceptable stability margin. The algorithm of forming the volume of control actions is based on the dependence of the value of control actions on the value of stability reserves estimation by the value of the Jacobi determinant. To build this dependence, the algorithm of searching for the limiting mode by the trajectory of change in the equilibrium position of the steady state of the system from the initial to the limiting one is used. In contrast to the existing algorithms, the proposed algorithm establishes a functional dependence of the control value on the current parameters of the regime or the stability margin, which increases the efficiency of calculations for selecting control actions. Realization of the proposed algorithm is carried out on the basis of the functional scheme according to the data of the vector measurement system.
The advantage and novelty of the proposed algorithm is the possibility of eliminating the disadvantages of existing systems of mode automation, the main of which are:
– the necessity to perform numerous variant calculations for selecting the volume of control actions;
– possible excessive volume of control actions in case of a mismatch of the actual mode with the calculated one
Identification of the oxidation and hydrolysis products content influence on the rapeseed oil oxidation induction period
Authors: Stankevych Serhii , Gorbunov Kostiantyn , Zabrodina Inna , Popov Mykola , Kalyna Viktoriia , Novozhylova Tetiana , Falalieieva Tetiana , Ovsiannikova Tetiana , Ponomarova Maryna , Zolotarov Andrii
Published: September 2024

The object of the study is the dependence of the induction period of rapeseed oil on the content of oxidation and hydrolysis products. A feature of the work is determining the approximation dependence of the induction period of accelerated oxidation of refined rapeseed oil on the content of primary oxidation products and free fatty acids. This is useful when predicting the shelf life of refined rapeseed oil. It was determined that both factors negatively affect the oxidation stability of refined rapeseed oil. An increase in the peroxide value decreases the induction period of model oil samples by 32.8512 units for each additional mmol ½ O/kg. In turn, increasing the acid value of oil samples reduces the induction period by 19.8424 units for each additional mg KOH/g. Different oxidation dynamics of model samples of refined rapeseed oil with tocopherol were revealed, depending on the concentration of primary oxidation and hydrolysis products. The obtained data are explained by the fact that the primary lipid oxidation products are unstable and quickly decompose to form free radicals. These radicals initiate further lipid oxidation, resulting in reduced oil quality. In addition, free fatty acids are more reactive than triglycerides and are more easily oxidized. A feature of the obtained results is the possibility of modeling processes that affect the oxidation stability of refined rapeseed oil. From a practical point of view, the research results allow initiating measures to maintain the safety of oil-containing food products based on refined rapeseed oil. An applied aspect of using the scientific results is the possibility of rationalizing the storage conditions of refined rapeseed oil to maximize its shelf life and increase competitiveness
Designing a toolset for assessing and implementing the potential of energy-saving economic development of enterprises
Authors: Lesinskyi Valentyn , Yemelyanov Olexandr , Zarytska Oksana , Petrushka Tetyana , Myroshchenko Nataliia
Published: September 2024

The object of this study is the evaluation and implementation of the potential of energy-saving economic development of enterprises. The task to design an effective toolkit for evaluating and implementing the specified potential was resolved.
The theoretical principles of formation and measurement of the level of energy-saving economic development of enterprises have been substantiated. A procedure for assessing the potential of energy-saving economic development of companies has been devised. This procedure involves determining the possibilities of enterprises to ensure simultaneous growth of economic results and the level of energy efficiency through the development and implementation of an optimal program of measures for such growth. The mechanism for implementing the potential of energy-saving economic development of enterprises on the basis of identifying and overcoming the main obstacles that appear on the way to such development has been improved.
The proposed theoretical and methodological approaches to the assessment and implementation of the potential of energy-saving natural gas economic development of enterprises was verified on a sample of 110 enterprises in the western region of Ukraine. In particular, it was established that the estimated potential of energy-saving natural gas economic development of the studied enterprises is very high. In particular, for more than 50 % of enterprises in all three industries, the value of this potential exceeds 6 %. At the same time, enterprises with a higher level of energy-saving economic development in the reporting period were characterized by a smaller value of this potential at the end of that period.
The toolkit proposed in this study could be used by enterprises of all types of economic activity when assessing the potential of their energy-saving economic development and when devising measures to implement the specified potential. This would help improve the economic efficiency of companies
Identification of the effect of ripening conditions on the yield of rose hips and their processed products
Authors: Fataliyev Hasil , Isgandarova Simuzar , Gadimova Natavan , Mammadova Aynur , Ismailov Mehman , Mammadzade Muhammad
Published: September 2024

Wild rose hip fruit, pulp, beverage, nectar, as well as technological methods and tools are taken as the object of research.
Rose hips have a, bright red color and a rich chemical composition, which makes it a very important raw material for industry. However, insufficient research slows down this work and makes the use of raw materials inefficient. With this in mind, the aim was to study the mechanical and technological characteristics of the femur, which are considered important for industrial processing.
The reflection of ripening conditions on the mechanical, physical and chemical properties of rose hips, as well as the influence of processing methods, especially hot processing, on the quality of the product has been established.
Research has shown that the percentage of fruit cultivation in the Dashkasan region was the lowest, and the highest in the Gadabay region, and the Goygol region took an intermediate position. The Latin hardness of fruits grown in Dashkasan region was 6.41 N. Gadabay region with 5.56 N and Goygol region with 5.47 N. This indicator plays an important role in the storage and processing of fruits. As a result of the treatment, the amount of dry matter in fruit, pulp and beverage increased slightly, titratable acids, ascorbic acid and pH decreased. An increase in total phenolic compounds was observed during the initial heat treatment of the raw material and was noted to be much lower in the pulp and beverage. Hot treatment had a reducing effect on the amount of ascorbic acid, which is considered one of the main components of indicators in the thigh. The obtained results can be used in individual family farms and in the food industry
Improving the technological process of balancing electric machine rotors on a balancing machine
Authors: Shostak Yaroslav , Holovashchenko Oleh , Reshetnikov Yuriy , Tkachenko Viktor
Published: September 2024

The object of research is the process of dynamic balancing of rotors on a balancing machine in the process of restoring electric machines.
The work is aimed at improving the quality of balancing rotors in the process of major repairs of traction electric motors for electric trains. The problem addressed was the quality of balancing the rotors of electric machines on stationary balancing machines. According to the conventional balancing technology, the rotor to be balanced is mounted on the supports of the balancing machine with support surfaces that usually have mechanical defects. These defects cannot be eliminated by machining due to the peculiarities of rotor repair technology. Theoretical and experimental studies of the effect of damage to the rotor support surfaces on the balancing parameters have been carried out. It has been proven that the properties of the bearing surfaces of the rotor during its balancing on a balancing machine significantly affect the results of determining the imbalance. At the same time, the difference in the mass values of balancing loads can reach 25 %. This is because damage to the bearing surfaces of the rotor generates false signals unrelated to the imbalance.
In order to increase the accuracy of determining the mass of balancing loads during rotor balancing, it is proposed to improve the technological process of balancing. The improvement involves the inclusion of a frequency filter in the signal conversion chain of acceleration sensors. The filter is designed to separate signals with a frequency greater than the rotational frequency of the rotor.
A condition for the practical application of the research results is the expediency of introducing a frequency filter of signals of acceleration sensors with a threshold frequency of filtering signals that exceeds the rotational frequency of the rotor into the schematic diagram of the balancing machine.
Ultra-performance liquid chromatography-mass spectrometry methods for the determination of the residual quantities of ramipril and hydrochlorothiazide for controlling the cleaning of equipment
Authors: Typlynska Kateryna , Kondratova Yuliya , Horyn Mariana , Logoyda Liliya
Published: September 2024

Monitoring the completeness of equipment cleaning is essential to prevent cross-contamination of medicinal products. Therefore, it is necessary to develop fast and sensitive methods for studying residual quantities of active ingredients on the surfaces of technological equipment.
The aim of the work was to develop and validate analytical methods for the determination of ramipril and hydrochlorothiazide in wash waters by ultra-performance liquid chromatography–mass spectrometry method.
Materials and methods. In the study, standard samples of ramipril (USP RS) and hydrochlorothiazide (USP RS), as well as class A reagents, were used. Samples were analysed on a liquid chromatograph with an MS detector (Agilent 6420 and Waters Xevo TQD ACQUITY). We used the Kinetex C18 column (2.1 mm × 30 mm × 1.7 μm); mobile phase – 0.1% formic acid solution in deionised water – Acetonitrile (ratio 73:27 for the determination of ramipril and 91.5:8.5 for the determination of hydrochlorothiazide); mobile phase rate of 0.4 mL/min for the determination of ramipril and 0.35 mL/min for the determination of hydrochlorothiazide; column temperature 45 °C for the determination of ramipril and 40 °C for the determination of hydrochlorothiazide, ionisation mode - electric spray in positive mode; The detection parameters are the mode of registration of the daughter ion 417 → 234 m/z for the determination of ramipril and 298 → 281 m/z for the determination of hydrochlorothiazide.
Results and discussion. Methods for the determination of ramipril and hydrochlorothiazide in wash waters by ultra-performance liquid chromatography–mass spectrometry have been developed. The developed methods have sufficient linearity, correctness and precision. The sensitivity of the techniques was confirmed at the level of 0.0026 μg/ml. The techniques can be used in the concentration range of 0.0026 – 0.0255 μg/ml
Conclusions. Analytical methods for determining ramipril and hydrochlorothiazide in wash waters have been developed and validated.
The Role of Anglo-Saxon Countries in Maintaining the American-led Order in the Indo-Pacific Region
Authors:   Kazimierz Wielki University in Bydgoszcz (Poland), Jureńczyk Łukasz , Kuź Adam ,   Kazimierz Wielki University in Bydgoszcz (Poland)
Published: September 2024

The analysis is based on theoretical assumptions characteristic of the multi-order world by Trine Flockhart concept. The main factor influencing the situation in the Indo-Pacific region is the conflict between two international orders, Chinese-led and American-led, which is economic but may take a military form in the future. The practical limitations of the article result from the complex process of analyzing and forecasting political phenomena in statu nascendi. The analysis contributes to the scientific discussion on the future of international relations in the Indo-Pacific region. The American-led order in the Indo-Pacific region is based on the institutionalized forms of cooperation involving Anglo-Saxon states based on identity factors determining their effectiveness. The US strategy for the Indo-Pacific is mainly based on the network of partnerships with the region’s countries and countries from other parts of the world supporting the American-led order in the region, especially the Anglo-Saxon countries. In addition to identity factors, the positive long-term experience of military cooperation between the Anglo-Saxon countries is significant. The escalation of the global conflict between the US and China will be conducive to further tightening this cooperation.
Methanolic Extract of Morchella esculenta (Ascomycota) Prevents Chemotherapy-Related Cardiotoxicity in Tumor-Bearing Mice
Authors: Das Sneha , Mathew Anit , Janardhanan Kainoor Krishnankutty
Published: September 2024

The quest for bioactives that confer protection against chemotherapy induced cardio toxicity is a front-line area of cardio oncology research. Species of genus Morchella have been used in traditional medicine to treat asthma, wound healing, cough, cold, indigestion, excessive phlegm and breathlessness. M. esculenta, commonly known as guchhi in India is a highly prized culinary morel mushroom. Recent studies carried out in our laboratory have demonstrated significant cardioprotective effect of M. esculenta against doxorubicin (DOX)-induced cardiotoxicity. Since bioactive extracts of morel mushrooms were found to possess profound antioxidant activity, the possible interference of these extracts with antineoplastic activity of chemotherapy drugs is often surmised. The current study was undertaken to evaluate the effect of two anticancer drugs, DOX and cyclophosphamide (CP) on solid tumor-bearing mice treated with bioactive extract of M. esculenta. Solid tumor was induced by subcutaneous injection of Dalton's lymphoma ascites (DLA) cells on the right hind limbs of Swiss albino mice. Animals were administered with various concentrations of methanol extract (ME) of M. esculenta following tumor induction. Tumor growth (volume and mass) was measured for four weeks after tumor induction. Cardioprotective effect of methanolic extract was assessed by determining cardiac injury markers levels in serum, antioxidant status in myocardium and histopathology of heart tissue. The results showed significant cardioprotective effect of ME of M. esculenta on tumor-bearing mice. The findings also suggest that ME of M. esculenta did not delimit the therapeutic effect of DOX and CP despite its profound antioxidant activity.
Ortaokul Öğrencilerine Deyim Öğretiminde Dijital Öykü Kullanımının Başarıya ve Kalıcılığa Etkisi
Authors: Toygar Yavuz Selim , Şengül Kübra
Published: September 2024

Çalışmada deyimlerin öğretiminde dijital öykü kullanımının başarıya etkisinin incelenmesi amaçlanmıştır. Karma yöntemin kullanıldığı araştırmanın nicel boyutunu tek gruplu öntest-sontest deneysel desen, nitel boyutunu ise olgubilim çalışması oluşturmaktadır. Çalışma grubu, 2021-2022 eğitim öğretim yılında Nevşehir ilindeki bir ortaokulun 7. sınıfında öğrenim gören 22 öğrenciden oluşmaktadır. Veri toplama araçları olarak araştırmacılar tarafından geliştirilen deyimlere ilişkin başarı testi ve yapılandırılmış bireysel görüşme formu kullanılmıştır. Araştırma sürecinde 7. sınıf Türkçe ders kitabında uygulama dönemine denk gelen metinlerde tespit edilen 26 deyim araştırmacıların hazırladığı öykülerde işlenmiş, son olarak hazırlanan öyküler dijital öykü biçimine getirilmiştir. Öntest ve sontest olarak deyimlere ilişkin başarı testi uygulanmıştır. Bu süreç içerisinde yapılandırılmış bireysel görüşme formu aracılığıyla çalışmaya ilişkin nitel veriler toplanmıştır. Uygulama bitiminden 3 hafta sonra ise kalıcılık testi uygulanmıştır. Elde edilen nicel verilerin analizi sonucunda dijital öykülerin deyim öğretimindeki başarıyı artırdığı ve öğrenmede kalıcılık sağladığı ve nitel verilerin analizi sonucunda ise dijital öykülerle deyim öğretiminin öğrenciler tarafından eğlenceli, kolaylaştırıcı ve öğretici birer etkinlik olarak görüldüğü tespit edilmiştir.
PARAZİT FİLMİNİN PİERRE BOURDİEU’NUN ALAN VE STRATEJİ KAVRAMLARI PERSPEKTİFİNDEN ANALİZİ
Authors: Ateşoğlu Nadir
Published: September 2024

Bu çalışmanın amacı “Parazit” filmini, Bourdieu’nun alan ve strateji kavramları çerçevesinde ve sınıf farkları ve eşitsizlikler bağlamında ele almaktadır. Pierre Bourdieu'nun "alan" kavramı, belirli bir toplumsal yapının içindeki belirli bir uzama veya faaliyet alanına atıfta bulunur. Bu alanda bireyler, belirli bir rekabet içinde sosyal ilişki ve etkileşim içinde bulunurlar. “Stratejiler” ise bireylerin belirli hedeflere ulaşmak ve belirli sonuçları elde etmek için kullandıkları plan ve taktiklerdir. Kavramsal çerçevesini Bourdieu’nun alan ve strateji kavramlarının oluşturduğu bu çalışmada bir aktör olarak bireylerin kendi konumlarını korumak veya lehlerine değiştirmek için eşitsizliklere karşı ne tür stratejiler kullandıkları ve alana giriş denemeleri ele alınacaktır. Çalışma, filmde alana giriş için bireylerin (Kim ailesi) kullandıkları stratejileri içerik analiz yöntemi kullanarak çözümlenmeyi amaçlamaktadır. Makalede bir sosyal sınıf veya tabakaya mensup olmanın bireyin davranışlarını temelden etkilediği sonucuna ulaşılmaktadır.
1930 İZMİR SEL AFETİ
Authors: Karataş İsrafil
Published: September 2024

Türkiye coğrafyası, yüzyıllardan beri çeşitli doğal afetlere maruz kalmış ve afetler önemli ölçüde can mal kayıplarına eden olmuştur. Dünyada olduğu gibi Türkiye’de de depremlerden hemen sonra en fazla kayıplara neden olan doğal afet, sellerdir. Zaman zaman aşırı yağışlarla dolan akarsu yatakları, taşarak çevresindeki yerleşim yerlerine ve tarımsal alanlara oldukça büyük zararlar vermişlerdir. Şehir planlamasındaki hatalar, akarsu yataklarında gerekli tedbirlerin alınmaması ve altyapının zayıflığı gibi nedenler İzmir’de Cumhuriyetin ilk yıllarında sellerin, afete dönüşmesine neden olmuştur. 1922 yılında düşman işgalinden kurtulan İzmir şehri, henüz yaralarını saramadan deprem ve sel afetleri ile mücadele etmek zorunda kalmıştır. İzmir’de yaşanan sel afetleri içerisinde en çok can ve mal kaybına neden olan ve insanların hafızasında yer edineni 1930 İzmir sel afetinin olduğu söylenebilir. Zira bu afette; sayısı tam olarak tespit edilememekle birlikte 117’den fazla insan vefat etmiş, selden binlerce kişi etkilenmiş ve milyonlarca lira zarar ortaya çıkmıştır. Bu çalışmada hedeflenen; 1930 yılı İzmir sel afetinin sebeplerini, etkilerini ve sonuçlarını doğal afet tarihi açısından ele alarak irdelemektir. Bunun yanı sıra, afet yönetiminde başarılı olunup olunmadığını ve bundan sonra bölgede olası sel afetleri karşısında ne gibi tedbirler alındığını ortaya koymaktır.
ASSESSMENT OF THE POSSIBILITY OF USING A CO₂-BASED BUFFER WHEN ORGANIZING UNDERGROUND GAS STORAGE FACILITIES
Authors: Anikeev D.P. , Indrupsky I.M. , Anikeeva E.S.
Published: September 2024

The burial of CO2 in geological structures is considered to be current direction for reducing the negative impact of anthropogenic load in the form of greenhouse gases. Underground storage is also evaluated as a potential way to balance hydrogen production and consumption. The planned production of hydrogen in Russia by 2030 is expected to reach several billion m3 per year. To ensure the production and transportation of such volumes of gas, a hydrogen storage system is needed. Above-ground complexes and storage facilities in salt caverns cannot provide the required storage volumes. Aquifers are promising objects for long-term storage of both CO2 and hydrogen, including as part of a hydrogen-methane mixture.The work considers a hydrogen-methane mixture with a hydrogen concentration of 10–30 %, which is an economically justified value in most cases when producing this mixture.When storing hydrogen long-term in underground gas storage facilities, an important task is to assess hydrogen losses during storage.The authors, using linear hydrodynamic models taking into account phase transformations and hydrochemical effects, assessed the effectiveness of simultaneous CO2 burial and underground hydrogen storage through the injection of a hydrogen-methane mixture with a CO2 buffer rim.The models under consideration take into account: changes in the ionic composition of formation water, dissolution and precipitation of minerals.Analysis of the results showed that CO2 is not an effective buffer for the hydrogen-methane mixture even under the simplified conditions of the linear model. In this model, the region with a high hydrogen content disintegrates. At the same time, linear models do not take into account a number of negative factors that arise during the creation and operation of a full-fledged underground gas storage facility.
IoT-ENHANCED SHALE OIL AND GAS GREEN DEVELOPMENT: STATUS AND FUTURE
Authors: Zhou Rongji , Wei Jianguang , Wang Anlun , Zhou Xiaofeng , Sultanov Sh.Kh.
Published: September 2024

Shale oil and gas, deemed as vital alternative resources to conventional oil and gas, have spurred significant interest in information-based exploration and development technologies within the industry in recent years [1]. China boasts extensive shale oil and gas reserves, with the International Energy Agency (EIA) estimating China's shale oil technology capable of extracting approximately 4.393 billion tonnes, ranking third globally. Additionally, China holds shale gas geological resources of about 134.4 trillion cubic meters, ranking first worldwide, showcasing immense development potential. Shale oil and gas, being unconventional resources, are distributed within the pore and fracture systems of organic-rich shale formations. Compared to conventional oil and gas, shale oil and gas exhibit weaker trap control and stronger distribution continuity, typically characterized by poor reservoir physical properties. Conventional extraction methods often struggle to yield industrial oil and gas flow from shale oil and gas resources, necessitating unconventional development technologies such as reservoir monitoring, directional wells, horizontal wells, and segmental fracturing [2]. However, these technologies come with challenges and risks, including complex production operations, high production data density, and environmental concerns such as surface ecological damage and pollutant emissions, further impacting shale oil and gas production. To facilitate the upgrading process of China's shale oil and gas industry, this paper presents the current status of Internet of Things (IoT) application technologies for shale oil and gas development and proposes a research outlook based on the concept of green development. Against the backdrop of energy transformation, it offers a reference framework for the sustainable development of China's extensive shale oil and gas resources.
EXPERIMENTAL STUDY ON THE FRACTURE CONDUCTIVITY IN SHALE OIL PRODUCTION
Authors: Ying Yang , Huan Chen , Jiangguang Wei , Gayubov A.T. , Qiaofeng Zhou , Nuriev A.A. , Chilikin V.M.
Published: September 2024

Unconventional oil and gas resources, such as shale oil and gas, are gradually attracting great attention from all countries of the world. Horizontal drilling and large-scale hydraulic fracturing technology are used to efficiently extract oil from shale formation. Effective placement of the proppant in the fractures and high long-term conductivity are the keys to solve the problems of oil well flow rate increase in shale oil and gas fields. In this work, the sieve analysis method and FCMS-V fracture conductivity determination device, as well as scanning electron microscope are used. They are used to experimentally investigate the filtration characteristics of hydraulic fracturing fractures and establish the key factors affecting the filtration characteristics. The object of the study is the core of the oil-saturated DG shale formation of Songliao Basin. Also in this paper, the indentation and crushing mechanism of proppant under reservoir conditions is studied. The influence of various factors was evaluated qualitatively and quantitatively. The following studies were conducted: the effect of sand granule size on conductivity, the effect of grain size distribution on conductivity, the effect of proppant concentration on conductivity, the effect of fracture closure pressure on conductivity, and the effect of proppant indentation on conductivity. The granule sizes of the proppant used range from 30/50 to 70/140 mesh. Proppant concentration: 2,5; 5; 10 kg/m2. Ratios of granule sizes for used mixtures: 1:1:1, 1:2:7, 1:4:5.And crack clamping pressure from 20 to 40 MPa. As a result of the study, dependences of initial and long-term fracture conductivity on clamping pressure, granulometric composition of proppant and its concentration were obtained. Using a scanning electron microscope, the degree of indentation and crushing of proppant under reservoir conditions in two media, namely shale core and steel plates, was visually evaluated. The results of experimental studies can be used to optimize the shale oil development system and have scientific and practical significance for shale oil production in continental deposits.
DEVELOPMENT OF SCIENTIFIC FOUNDATIONS AND METHOD OF AUTONOMOUS POWER AND GAS SUPPLY OF REMOTE CONSUMERS FROM GAS DISTRIBUTION NETWORKS
Authors: Mingazeva K.A. , Karimov R.M. , Dmitriev M.E. , Kuskildin T.R. , Tashbulatov R.R. , Nurmuhamedov Ch.I.
Published: September 2024

The development and implementation of independent power supply systems with a high degree of autonomy is becoming an urgent task for the development of remote and inaccessible regions of the country, both due to the lack of energy capacities and accessible networks in newly developed areas, and the high cost of allocating separate power lines for remote and compact settlements. The increase in the scale of central networks is associated with high capital investments and long project implementation time, which creates inconvenience for consumers and the development of small and medium-sized enterprises. At the same time, unlike power supply, gasification issues, which are actively being resolved in all regions of the country, make it possible to connect new consumers of natural gas several times faster and cheaper, which is due to the high manufacturability and speed of construction of polyethylene gas pipelines of distribution networks, provided that gas pipelines pass in the region. In addition to lower capital and operating costs, the process of transporting energy resources through pipelines in the form of a primary source — gas — is characterized by significantly lower losses compared to water and electricity. At the same time, network gas in combination with trigeneration technologies and cryogenic hydrocarbon storage can be used not only as boiler fuel, but also as motor fuel, a source for generating electricity, heat and even cold with a replenished autonomous reserve. Thus, as an alternative solution to traditional power systems, it is proposed to use hybrid power systems — systems based on trigeneration plants with gas piston installations, turbine and screw machines, as well as cryogenic gas storage facilities that can provide the population with electricity, heat, cold and motor fuel. The article analyzed the state and development of the fuel and energy complex in Russia, conducted a study of the needs for heat, gas and electricity for an average compact settlement with small and medium-sized enterprises. Analysis and selection of equipment parameters for uninterrupted autonomous power supply of the economy was carried out.
ANALYSIS OF THE CHANGE IN THE RHEOLOGICAL CURVE OF THE FLOW OF NON-NEWTONIAN OILS IN THE FIELDS OF WESTERN KAZAKHSTAN
Authors: Serkebaeva B.S. , Sayenko O.B. , Sultanov Sh.Kh. , Turkpenbaeva B.Zh. , Manapov T.F.
Published: September 2024

In order to improve oil recovery technologies, the task of studying the rheological properties of oil, which largely determine the development indicators of the development target, namely, the rate of oil withdrawal, the stability and nature of the movement of the front of displacement of oil by water or gas, and, as a result, final oil recovery, is becoming urgent. In this regard, there is a need for in-depth studies of the rheoviscidity properties of produced oils.This article presents the results of laboratory studies to study the rheological characteristics of both high-paraffin and heavy high-viscosity oils using the example of oil from fields in Western Kazakhstan. Since structured oils are thixotropic systems, all experiments were carried out with the same degree of structure destruction in oil, both anhydrous oils and those with different water cuts were studied. The authors also showed the nature of the change in the rheological curve of the flow of oil emulsion of various water cuts to identify the temperature interval where non-Newtonian properties of various oils are manifested. Their main physical and chemical properties are also given, and kinematic viscosities of oil with different densities are compared. The results of laboratory studies of viscosity change with temperature increase for Karazhanbas oil emulsion with different water cut are considered. Despite differences in viscosity values of different degrees of watered samples of highly paraffinic oil, the tendency of oil viscosity change depending on the shear gradient is the same. The formation of structured systems of resin and asphaltene particles is observed in flows with relatively low shear gradients. As a result, oil viscosity dependence on the shear gradient in the range of low values from 0 to 20 s-1 must be taken into account when solving tasks for high-paraffin production. The results obtained are of practical interest, since when creating a compositional model and technological modeling of the collection and transport system, the rheological characteristics of the oil of a particular field, as well as the presence of thixotropic properties, must be taken into account.
EXPERIMENTAL STUDY OF HYDRATE FORMATION PECULIARITIES FOR CONDITIONS OF THE TURNO AND CENOMANIAN DEPOSITS: Part II
Authors: Kishalov A.E. , Lipatov V.D. , Savichev V.I. , Litvinenko K.V. , Yagudin R.A. , Khayrislamova R.N.
Published: September 2024

This paper is the second part of the research devoted to the study of hydrate formation features for the conditions of Turonian and Cenomanian deposits. The launch of new gas projects at the Turon and Senoman production facilities in Western Siberia provided a good opportunity to critically analyze the known methods of protecting production, gathering and transportation facilities of the gas field from the formation of solid gas hydrates. The paper presents the experience of implementing a program of laboratory studies of conditions of gas hydrate formation with their subsequent processing and in-depth analysis. The research program covered the area of thermobaric parameters typical for the conditions of Turon-Senoman deposits exploitation with localization of hydrate-hazardous areas in the conditions of Technological Regimes for full development. The description of laboratory studies is given, in which two gas compositions of Senoman and Turon objects, different variants of mineralization and ionic composition corresponding to formation and condensation water, as well as hydrate formation conditions under changing dosages of basic inhibitor on the basis of methanol were considered. The details of the experiment based on the method of swinging cells and the subsequent analysis of the results of the completed experiments to determine the thermobaric conditions of formation and decomposition of hydrates are given. The main features of the experiment are specified, estimates of the rate of change of the influencing parameters of the experiment on its quality are given. In the process of implementation of the experimental program, the optimal values of these parameters were selected, which allowed us to significantly reduce the variation of experimental results to determine the thermobaric conditions of hydrate formation. It is experimentally established that the temperature of hydrate decomposition is higher than the temperature of its formation at all investigated gas compositions and water mineralization.
PRODUCTION OF CARBON DIOXIDE CORROSION INHIBITORS OF STEEL FROM DIAMINES AND TALL OIL FATTY ACIDS
Authors: Telin A.G. , Fakhreeva A.V. , Bayanov R.R. , Sergeeva N.A. , Ragulin V.V. , Dokichev V.A.
Published: September 2024

Substituted imidazolines are one of the most common and effective surface-acting metal corrosion inhibitors. The main tasks of today are to reduce their cost and increase their hydrolytic stability, which is achieved through a targeted choice of the nature and structure of long-chain carboxylic acids in the synthesis of imidazolines. Another way to reduce the cost of producing corrosion inhibitors based on aliphatic ethylenediamines is to use imidazoline precursors – amidoamines and ammonium salts - to protect against corrosion, the production of which is much less energy-consuming.The synthesis of active substances of carbon steel corrosion inhibitors in the reaction of diamines with fatty acids of tall oil was carried out. It is shown that depending on the temperature of the reaction and the introduction of the catalyst – polycationite CU-2-8 - it is possible to selectively obtain derivatives of imidazolines, amidoamines, and ammonium salts, which are capable of inhibiting carbon dioxide corrosion of steel in mineralized water at 60 °C with a degree of protection from 85 % to 91 %. It is noted that the protective effect of amidoamines and ammonium salts is practically not inferior to the action of imidazolines.
TECHNOLOGICAL COMPLICATIONS (FORMATION DAMAGE) DURING CO2 INJECTION FOR ENHANCED OIL RECOVERY. Part 2. INTERACTION OF CO2 WITH FORMATION OIL: WETTABILITY CHANGE, ASPHALTENE PRECIPITATION AND DEPOSITION IN THE FORMATION
Authors: Voloshin A.I. , Volkov M.G. , Dokichev V.A.
Published: September 2024

In the second part of the review (the first part was published in [1]) the processes of formation damage at CO2 injection due to the oil phase stability disturbance are considered. Changes in reservoir temperature, pressure or fluid composition due to CO2 dissolution can provoke asphaltene precipitation and deposition. Their adsorption on the reservoir pore surface leads to a change in decrease in rock permeability. The currently ac wettability and a cepted numerical models describe well the experimental results on colmatation of pore media by asphaltenes in the presence of CO2, with different equations for asphaltene adsorption and kinetics of their occurrence being used in the models. Asphaltenes precipitated in pore volumes migrate with formation fluids to production wells and can form deposits that complicate oil production.
Association between cacti and nurse plants: a quantitative literature review
Authors: Snell Cordero Jessica , Godínez-Alvarez Héctor
Published: September 2024

The association between cacti and nurse plants has been reviewed by different authors. These reviews however were qualitative because only evaluated aspects such as species identity of cacti and nurse plants, probable explanatory causes of their association, and location of study sites. To our knowledge, there are no quantitative reviews that have evaluated the association between cacti and nurse plants for different subfamilies, tribes, and growth forms of cacti and nurse plants, and different plant communities and soil properties. To address these issues, we performed a quantitative review of the studies on the association between cacti and nurse plants. The studies were searched in the ISI Web of Knowledge from 1986 to 2021. Data obtained from studies were analyzed with the relative risk ratio and ratio of medians. Most studies on the association between cacti and nurse plants were performed mainly in Mexico and the USA. Globose, cylindrical, and columnar cacti of the subfamily Cactoideae, and tribes Cacteae, Cereeae, and Echinocereeae  were associated to nurse plants of Asteraceae, Euphorbiaceae, and Fabaceae. However, other subfamilies (Opuntioideae) and tribes (Notocacteae) of cacti, and families (Asparagaceae) of nurse plants were not associated. Nurse plants ameliorated temperature, moisture, and nitrogen of soil. The association between cacti and nurse plants occurred in desert shrubland and tropical dry forest. Further studies are needed on the association between cacti and nurse plants that consider more cactus subfamilies and tribes in countries with high cactus diversity in Central and South America.
Am I a Mole or a Snake? The Direction of the Production of Knowledge
Authors:   Stasis Center for Practical Philosophy, European University at St. Petersburg (EUSPb), Russia, Regev Yoel , Petuk Alek ,   Coincidentalist Institute, Moscow, Russia
Published: September 2024

The article considers the issue of the “coincidentalist turn” in contemporary art — a radical change in the mode of functioning of a work of art. Based on the onto-economic turn carried out by the materialist dialectic of coincidence, which asserts the holding-together of the divided as a substance, the coincidentalist turn allows to liberate art from the “reservation of the aesthetic” and make it a technique of clarifying and transforming of the real that extends to all areas of life. The article places the “coincidentalist turn” in the context of the art history of the last decades. The theoretical sections of the article outline the main provisions of the coincidentalistic theory in their relation to the problems of art. Practical sections are dedicated to the description of specific types of activities that have appeared in recent years and are the first experiments in the construction of “clarification machines” based on calculus methods made possible by coincidentalist theory. They are based on the analysis of real experimental data of the moderation of extended seminars “K-fitness” and “The door doesn’t open from this side” by the Council of the Coincidentalist Institute. The form of the presentation coincides with the basic metaphysical formula of coincidentalist ontology: 2/4 (two divided by four). The theoretical and practical sections are divided into comments by a philosopher and an engineer.
Third Renaissance or The New Middle Ages? Russian Silver Age on the Renaissance
Authors:   Financial University under the Government of the Russian Federation, Moscow, Matveychev Oleg
Published: September 2024

The article is a historiographical and theoretical review of the views of representatives of Russian religious and philosophical thought of the late 19 — early 20 centuries on the topic of the Western European Renaissance. The article analyzes the history of the concept of “Renaissance” since its introduction into scientific use by Jules Michelet (1855) and Jacob Burckhardt (1860). The Russian intelligentsia took this term in the interpretation of Friedrich Nietzsche, who contrasted the individualism and aristocracy of the Renaissance with the egalitarianism and philistinism of modernity. The Nietzschean concept of the Renaissance by Dmitry Merezhkovsky, who sought a solution to the great contradiction between paganism and Christianity and expected a Third Renaissance, is contrasted with the constructions of Akim Volynsky, who interpreted the Renaissance not as a revival of classical beauty and the emancipation of the creative forces of the individual, but as an anti-Christian, demonic movement, the restoration of dark pagan principles. The peculiar interpretations of the Renaissance and related concepts of the Third Renaissance by Thaddeus Zelinsky and Vyacheslav Ivanov are considered. The author emphasizes that enthusiasts of the Third Renaissance interpret the concept of “Renaissance” broadly — not only as the restoration of ancient ideals, but also as the renewal of culture in general, the path to a new state of culture and society. Hence the idea of the multiplicity of “rebirths” in history, associated with the idea of the cyclical nature of the historical process. It is noted that at the beginning of the 20 century, the attitude to the Renaissance in Russian philosophy is being rethought, the roots of the deepening crisis of modern society are found in it. The Renaissance is criticized as a phenomenon responsible for the desiccation and atomization of Western culture. The most consistent critics of the worldview of the Renaissance type were Nikolai Berdyaev and Pavel Florensky, who announced the imminent end of the Renaissance world, built on the principles of humanism and individualism, and the advent of the New Middle Ages.