bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise da Fisiografia da Microbacia São Nicolau, no Município de São João Evangelista - MG
Authors: Souza Jackson , Oliveira Gildriano , Cardozo Érica , Fernandes Paulo
Published: August 2024

A pesquisa em questão visa monitorar a fisiografia da Microbacia São Nicolau, localizada em São João Evangelista. Utilizando sensoriamento remoto, o estudo avaliará os parâmetros morfométricos mais relevantes para a área, além de investigar os processos biológicos dessa unidade geográfica. A análise foi conduzida por meio de geoprocessamento, focando nos aspectos morfométricos que são cruciais para compreender os processos físicos, químicos e biológicos que impactam o ciclo hidrológico da microbacia. A microbacia tem uma área de 239 km², sendo consideravelmente pequena. Isso facilita o controle de eventos hidrológicos menores dentro dessa área. Mediu-se o perímetro da bacia hidrográfica usando um curvímetro, obtendo 109,97 km para a microbacia São Nicolau. O Coeficiente de Compacidade (Kc) foi calculado como 1,99, indicando que a área não está propensa a enchentes. Com base nesses dados, é possível inferir que a microbacia tem uma forma alongada, já que o valor obtido corresponde a bacias com esse formato. Além disso, a Densidade de Drenagem (Dd) foi calculada em 15,32 km/km², caracterizando-a como uma área de boa drenagem.
Atualização no cuidado aos pés de pessoas com diabetes mellitus para enfermeiros da atenção primária: relato de experiência
Authors: Mortari Belaver Guilherme , Reinert Maria Juliana , Pereira Milena , Fernandes Soares Cilene , Soldera Daniela , Balbinot Reis Girondi Juliana , Ferreira Siqueira Elizimara
Published: August 2024

Objetivo: relatar a experiência de atividade educativa desenvolvida para atualização de enfermeiros da Atenção Primária no cuidado aos pés de pessoas com diabetes. Metodologia: estudo descritivo do tipo relato de experiência desenvolvido em um município do sul do Brasil. Foram realizadas oficinas entre março e abril de 2024. Utilizou-se de metodologias participativas a partir de recursos audiovisuais, imagens de casos reais e hands-on, tendo como público alvo os enfermeiros com duração de quatro horas, contabilizando o total de oito oficinas. Resultados: Foram capacitados 180 profissionais, com explanação de dados referente à epidemiologia do diabetes, exame físico utilizando instrumentos, com simulação nos pés dos participantes, condutas relacionadas às alterações encontradas e identificação de situações que ameaçam o membro a curto prazo. Houve o compartilhamento de experiências, discussão e reflexão sobre a temática em questão. Conclusão: conclui-se que o presente relato contribui para a práxis assistencial dos enfermeiros ao descrever a importância de capacitações através de oficinas que difundem as práticas de cuidado mais atuais aos pés das pessoas com diabetes mellitus.
Auriculoterapia para tratamento de sintomas de ansiedade em universitários
Authors: Alchieri Isadora , Renee Hilgemberg Glaucia
Published: August 2024

A ansiedade, sendo um problema que afeta diretamente o cotidiano dos indivíduos, vem se tornando cada vez mais preocupante. A Auriculoterapia entra como uma técnica que utiliza o pavilhão auricular para tratar e diminuir sintomas que o indivíduo venha a queixar-se. A pesquisa teve o intuito de verificar a eficácia da Auriculoterapia na diminuição dos sintomas de ansiedade em universitários. Foi aplicada em 20 acadêmicos, divididos em dois grupos que faziam ou não o uso de medicação para ansiedade. Como forma de avaliação dos sintomas foi utilizado o Inventário de Ansiedade de Beck (BAI). Obteve-se no geral dos voluntários uma média de 29,1 antes, e após a intervenção, diminuição para 14,9 mostrando muita significancia, sendo P - <0,001. Já os grupos que faziam ou não o uso de medicação tiveram valores parecidos no inicio e ao fim da intervenção, sendo os indivíduos que não faziam uso de medicação com média de 27,5 antes da intervenção e 13,1 após, e os que faziam uso, média de 30,7 antes e 16,8 após, trazendo assim, em valor de P - 0,598 mostrando que com ansiolítioco ou não a auriculoterapia trouxe resultados, não tendo grande diferença desses resultados.
Advanced nano-drug delivery systems utilizing natural product-based innovations
Authors: Alhabib Nasser Ali , Alehaidib Soliman Mohammed , Alharbi Omar Obaid , Alkhadrawi Mariam Adnan
Published: August 2024

Background: Natural products have historically played a crucial role in human health, spanning from early uses to modern medicine. Despite their extensive pharmacological potential, clinical applications are often limited by issues such as poor solubility and rapid metabolism. Aim: To explore the use of advanced nano-drug delivery systems to enhance the efficacy of natural products by overcoming their limitations and improving therapeutic outcomes. Methods: This review examines various nano-drug delivery systems that integrate natural products. It discusses advancements in nano-carriers, including liposomes, micelles, and self-assembled structures, focusing on their ability to improve drug solubility, stability, and targeted delivery. Results: Significant progress has been made in developing nano-carriers for natural products, including terpenoids, flavonoids, polyphenols, and alkaloids. Innovations such as targeting warheads and self-assembled systems have shown improved drug delivery and therapeutic efficacy in preclinical studies. Conclusion: Nano-drug delivery systems utilizing natural products offer promising solutions to overcome traditional limitations, enhancing drug bioavailability and targeted delivery. This advancement holds potential for revolutionizing the treatment of complex diseases and improving clinical outcomes.
Hubungan Pelaksanaan Timeout dengan Keselamatan Pasien di Kamar Operasi RSUD Khidmat Sehat Afiat (KiSA) Depok
Authors: Nuria Siti Mirza
Published: August 2024

Latar Belakang: Time out dimulai sebelum dilakukan insisi dan semua anggota tim operasi lengkap serta menyebutkan nama dan peran masing–masing dalam operasi tersebut.
Tujuan: Untuk mengetahui hubungan pelaksanaan Timeout dengan keselamatan pasien di kamar operasi  di RSUD KiSA Depok
Metode: Menggunakan rancangan penelitian kuantitataif dengan metode korelasional dan pendekatan cross-sectional. Instrumen yang digunakan dalam penelitian ini adalah kuesioner. Populasi dalam penelitian ini adalah staff yang bekerja di kamar operasi sebanyak 40 orang dengan menggunakan teknik total sampling yaitu jumlah populasi sama dengan jumlah sampel penelitian. Pengolahan data melalui tahap editing, coding, processing dan cleaning. Analisis data meliputi deskripsi data dan bivariat dengan menggunakan uji Chi- Square.
Hasil: Hasil uji statistik hubungan bermakna antara pelaksanaan time out dengan keselamatan pasien di kamar operasi di RSUD KiSA, Depok diperoleh nilai p-value = 0,000 < α 0,05. Hasil analisis didapatkan nilai OR = 116,000 artinya perawat yang melakukan pelaksanaan timeout dengan lengkap memiliki peluang 116,000 kali keselamatan pasien di kamar operasi lebih baik dibandingkan dengan perawat yang tidak lengkap melakukan pelaksanaan time out.
Kesimpulan: Terdapat hubungan bermakna antara pelaksanaan time out dengan keselamatan pasien di kamar operasi di RSUD KiSA Depok. Dengan penerapan budaya keselamatan pasien yang baik, maka akan tercapai sasaran keselamatan pasien.
Tujuan: Mengetahui hubungan pelaksanaan Timeout dengan keselamatan pasien di kamar operasi  di RSUD KiSA Depok
Metode: Menggunakan rancangan penelitian kuantitataif dengan metode korelasional dan pendekatan cross sectional. Instrumen yang digunakan dalam penelitian ini adalah kuesioner. Populasi dalam penelitian ini adalah staff yang bekerja di kamar operasi sebanyak 40 orang dengan menggunakan teknik total sampling yaitu jumlah populasi sama dengan jumlah sampel penelitian. Pengolahan data melalui tahap editing, coding, processing dan cleaning. Analisis data meliputi deskripsi data dan bivariat dengan menggunakan uji Chi Square.
Hasil: Uji statistic nilai p value 0,000 < α 0,05. Nilai OR = 116,000.
Kesimpulan: Terdapat hubungan bermakna antara pelaksanaan time out dengan keselamatan pasien di kamar operasi di RSUD KiSA Depok. Dengan penerapan budaya keselamatan pasien yang baik, maka akan tercapai sasaran keselamatan pasien.
Faktor-Faktor yang Mempengaruhi Kecemasan Pasien dalam Tindakan Hemodialisis
Authors: Iyarmasa Maria G , Handayani Yani , Novita Astrid
Published: August 2024

Latar Belakang: Berdasarkan studi pendahaluan pada tanggal 11 November 2022 yaitu dengan observasi awal dan wawancara yang dilakukan hasil wawancara pada 8 pasien gagal ginjal gronik. Hasil didapatkan pasien mengatakan mengalami kecemasan, Pasien yang melakukan terapi hemodialisis mengalami kecemasan, mereka cemas dengan terapi yang dijalaninya, cemas terhadap mesin, selang-selang dialiri darah dan cemas ditusuk dan cemas tidak bekerja seperti biasa, tampak raut putus asa diwajah pasien
Tujuan: Untuk mengetahui faktor-faktor yang mempengaruhi kecemasan pasien dalam tindakan hemodialisis di Rumah Sakit Pasar Rebo Jakarta Timur 2023
Metode: Desain penelitian yang digunakan adalah deskriptif analitik dengan metode cross-sectional. Populasi dalam penelitian ini adalah seluruh pasien yang sedang menjalani terapi hemodialisa di Rumah Sakit Pasar Rebo Jakarta Timur yaitu berjumlah 90 pasien. Penelitian ini menggunakan jenis non probability sampling dengan teknik purposive sampling. Besar sampel diambil sejumlah 73 orang. Metode pengumpulan data yang digunakan dalam penelitian ini terdiri dari 2 jenis metode, yaitu: Wawancara dan Observasi. Analisa bivariat dilakukan untuk melihat hubungan antara variabel independen dan dependen dengan menggunakan uji Rho Spearman.
Hasil: Berdasarkan hasil penelitian didapatkan hubungan pengalaman pengobatan pasien dengan kecemasan pasien dalam tindakan hemodialisis (p = 0.000). Hubungan konsep diri dengan kecemasan pasien dalam tindakan hemodialisis (p = 0.001). hubungan akses informasi pasien dengan kecemasan pasien dalam tindakan hemodialisis (p = 0.001). Hubungan proses adaptasi pasien dengan kecemasan pasien dalam tindakan hemodialisis (p = 0.000).
Kesimpulan: Ada hubungan pengalaman pengobatan pasien, konsep diri, akses informasi dan proses adaptasi dengan kecemasan pasien dalam tindakan hemodialisis di Rumah Sakit Pasar Rebo tahun 2023.
Optimization and validation of a liquid chromatography method with fluorescence detection for the determination of amines in fine atmospheric particulate matter
Authors: Alves Thais Fernanda , Brugin Priscila , Leal Rafael Junqueira , Solci Maria Cristina
Published: August 2024

Primary amines are pollutants present in the atmosphere in gaseous form or as particulate matter, emitted mainly by the industrial sector, vehicles, and biomass burning. There is concern about the concentration of amines present in the atmosphere, as the consequences of long-term exposure cannot be predicted. The objective of the present study is the optimization and subsequent validation of a method for determining amines in fine atmospheric particulate matter, using liquid chromatography and fluorescence detection. The optimization of the derivatization process was carried out through a 2² factorial design to improve the sensitivity of the method, determining that lower concentrations of the reagents o-phthaldialdehyde and 2-mercaptoethanol result in a more pronounced analytical signal. The optimization of the chromatographic method allowed the separation of four primary amines within 20 minutes of run time using solvents such as sodium acetate, methanol and tetrahydrofuran. The method validation showed good performance according to the results for selectivity and linearity, with detection limits of 0.121 to 0.284 ng m-³ and quantification of 0.398 to 0.938 ng m-³. The precision (>5%) and recoveries (82 to 117%) of the method are within recommended values. Therefore, the optimized method for determining amines allowed the application of the method to real samples of atmospheric amines, obtaining concentrations in Brazil comparable to other regions around the world.
Eduardo Coutinho, lado B
Authors: De Aquino Rodrigues Laécio Ricardo
Published: August 2024

O ensaio revisa parte da produção menos conhecida de Eduardo Coutinho, destacando algumas de suas singularidades, virtudes e possíveis contradições. São elas: O Fio da Memória (1991), Volta Redonda - Memorial da greve (1989) e Boca de Lixo (1992). Ao mesmo tempo, o estudo sugere que alguns temas e questões que despontarão na obra futura do diretor já se encontram prefigurado nestes títulos. Dentre eles, podemos citar: a preferência por personagens e situações ambíguas; o embate entre a escrita e a tradição oral; o risco decorrente dos encontros inesperados; a devolução da imagem como pressuposto ético; e a melancolia que permeia o mundo do trabalho.
Adolescent Idiopathic Scoliosis in Siblings Treated by Surgical Deformity Correction
Authors: Kim Hong Jin , Pizones Javier , Chang Dong-Gune
Published: August 2024

Adolescent idiopathic scoliosis (AIS) in siblings reflects genetic hypothesis; however, few studies have been published. Furthermore, to the best of our knowledge, there have been no reports in the literature of both siblings with AIS who underwent deformity corrections. A 15-year-old adolescent girl visited our clinic with back pain after recognition of the incidental findings of a scoliotic curve in the spine. Whole spine radiographs detected Lenke classification type 3CN. The patient underwent deformity correction with posterior instrumented fusion from T4 to L3 with thoracoplasty of the right 7th to 10th rib. Four years later, her 16-year-old younger brother also visited our clinic with back pain after recognition of the incidental findings of a scoliotic curve in the spine. Whole spine radiographs detected Lenke classification type 2AN. The patient underwent deformity correction with posterior instrumented fusion from T5 to L2 with thoracoplasty of the right 8th to 10th rib. In conclusion, we report on two siblings with AIS who underwent surgical treatment for different types of curves. They showed favorable outcomes after performing deformity correction with posterior instrumented fusion. Our rare case supports the underlying basis of genetic heterogeneity as a complex polygenic model.
Cardiovascular risk in an adolescent population of Timbío, Colombia
Authors: Clara Torres A. , Diego Illera , Darly Acevedo B. , Mayra Cadena M. , Luis C. Meneses M. , Paola A. Ordoñez H. , Lizeth N. Pantoja A. , Marcela Pastás C.
Published: August 2024

Introduction: Cardiovascular diseases are among the leading causes of death worldwide and the scientiﬁc evidence suggests that they have an origin at early ages, so reducing from adolescence the risks that contribute to their appearance is indispensable. Objective: To determine cardiovascular risk in the adolescent population of an educational institution in Timbío, Cauca, 2015 - 2016. Methodology: Quantitative, descriptive, observational and cross-sectional study. Sample: 100 students (47 females, 53 males), aged 10 to 19 years. Sociodemographic, anthropometric, biological, biochemical (glycemia), personal and family history, lifestyles and oral contraceptive use variables were evaluated. Results: A higher prevalence of cardiovascular risk was found in the adolescent age group (15-18 years) with 84.6%; the female gender presented a greater possibility of having cardiovascular risk (OR: 2.8, 95% CI 1.17 - 6.87); 7% reported regular tobacco use and 12% were passive smokers. The presence of unhealthy eating habits generated a higher cardiovascular risk (OR: 5.57, 95% CI 1.95-15.90). 67% (n= 67) have cardiovascular risk. Conclusions: Female gender, adolescent group (15-18 years), consumption of alcoholic beverages and unhealthy eating habits are associated with a higher possibility of having cardiovascular risk. Cardiovascular risk was found in a large percentage of the study population.
Virtual reality versus webinar trans healthcare training for emergency medicine residents: a feasibility study
Authors: Chisolm-Straker Makini , Daul Adrian , McNamara Shannon , Goldman Rhyan , Hajicharalambous Christina , Baluyot Mariju , Cole Michael , Clesca Cindy , Loo George , Janairo Maria-Pamela , Samuels Elizabeth A. , Westafer Lauren , Serrano Felipe , Goldstein Zil
Published: August 2024

Introduction

Transgender and gender non-binary (TGNB) patient care is not routinely taught in medical training. As a result, clinicians frequently lack knowledge regarding gender-affirming practices, surgeries and medications. TGNB-specific health knowledge and care delivery are further negatively impacted by pervasive societal transphobia. Virtual reality (VR)-based instruction may provide learners with opportunities for perspective taking, empathy building and attitudinal shifting to improve care delivery to TGNB patients.

Methods

This was a feasibility trial that compared passive VR and webinar in changing learner attitudes, knowledge and medical decision-making (MDM). Residents were recruited from five US emergency medicine (EM) residencies and were randomized to either VR or webinar educational intervention arm. Pre- and post-intervention assessments were matched using a unique identifier. Participants provided feedback about platform usability.

Results

From August 2020 to October 2021, 206 resident participants were randomized into a case-based VR experience or webinar intervention on TGNB-specific EM medicine; 52 residents completed all three steps of the study. Webinar participants demonstrated more changes in attitudinal statements than VR participants. No improvements in knowledge or MDM were appreciated in either intervention arm. Participants in both arms shared positive and critical feedback about the intervention they accessed, with convenience and ease of use being valued for asynchronous webinar learning.

Discussion

The webinar arm demonstrated a higher increase in empathy or change in attitude compared to VR learners. As VR becomes more technologically agile, accessible and reliable, more work is needed to see if this novel format is an educational tool that closely approximates the standardized patient encounter.
Factors Influencing Preservice Teachers’ Attitudes Towards Problem-Solving in Mathematics Education
Authors: Mohammed Atar Alphaa
Published: August 2024

This study explored the factors that predict preservice teachers’ attitudes toward incorporating problem-solving in teaching mathematics. Cognizance of the essential role of problem-solving in teaching and learning mathematics, the study underscored the latent variable that informs teachers’ attitudes concerning the incorporation of problem-solving in their mathematics classrooms. Employing a structured questionnaire and Exploratory Factor Analysis (EFA) with 360 preservice teachers in Ghana, the study acknowledged four key factors: Empowerment, Readiness, Commitment, and Perceived Usefulness. These findings open gateways to preservice teacher characteristics that inform their attitude toward problem-solving and recommendations to enhance teachers’ positive attitude toward the phenomenon.
Our experience in postoperative management of totallaryngectomy – A case series
Authors:   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India, Raj P. Karthik , Selvan V. Saravana ,   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India, Vivek M. ,   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India, Siddique S. Mohamed ,   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India, Kumar N. Suresh ,   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India, Kumar T. Ashok ,   Upgraded Institute of Otorhinolaryngology, Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai,India
Published: August 2024

Total Laryngectomy (TL) is recommended as a treatment for advanced laryngeal cancers, while salvage totallaryngectomy is performed as a secondary procedure after recurrence following laser surgery, radiation, orchemoradiation. Establishing comprehensive standards of care for patients undergoing total laryngectomy in thepostoperative period has proved challenging. Perioperative care continues to exhibit considerable variability, oftenrelying on anecdotal practices. The objective of this study was to disseminate our knowledge and expertise ona case series of patients who have undergone TL and the challenges we encountered during the postoperativeperiod and to identify postoperative complications risk factors and their management in the perioperative careof total laryngectomy patients. A retrospective analysis of 10 patients who underwent total laryngectomy at RajivGandhi Government General Hospital, Chennai, was included in the study. Four of them were cases of recurrentlaryngeal carcinoma following the initial failure of definitive radiation (RT), either with or without chemotherapy. 4out of 10 patients developed complications. Complications, primarily pharyngocutaneous fistulas were observedin 3 patients, which were managed surgically by flap cover closure. Complications occurred among patientswith risk factors for inadequate wound healing, such as comorbidities like diabetes mellitus and radiation, whichincreased hospital stay, antibiotic duration, and time to initiate oral feeds among reconstructed patients. Thisanalysis contributes insights into postoperative challenges and risk factors associated with complications in TLpatients.
Redefining endoscopic stapedotomy: a detailed exploration of endoscopic principles and surgical techniques
Authors:   Harshini Hospital, Madurai, Tamil Nadu, India, Rajiniganth M. G.
Published: August 2024

Objective: Our aim was to investigate the practicality, safety, and effectiveness of endoscopic stapedotomy (ES) for otosclerosis. To assess audiological outcomes and any complications that arose during our experience at the hospital. Methods: A Case Series of 42 patients underwent ES at our hospital between January 2021 and December 2023. Patients were carefully selected based on a confirmed diagnosis of otosclerosis, age (18 years or older), and no history of prior ear surgery or chronic middle ear issues. We diligently collected data on patient characteristics, surgical specifics, hearing outcomes, and any complications encountered and then analyzed this data to see how ES affected patients’ hearing and how safe it was. Results: Significant improvement in air conduction (AC), bone conduction (BC), and the air-bone gap (ABG) after surgery (p < 0.0001 for all). On average, the surgery took 31 min to perform. Complications were rare, with only a few patients experiencing mild vertigo. Notably, we had no cases of taste disturbance (dysgeusia) or eardrum perforation. As the surgeon gained more experience with ES, we noticed a trend toward shorter operating times and fewer complications. Conclusion: Our experience with ES suggests that it is a feasible, effectual, and the safest technique for treating otosclerosis. It offers significant benefits in terms of better visualization and less invasive surgery, but it does require specialized training. It is clear that a surgeon’s experience with this technique plays a significant role in achieving the best possible outcomes for patients.
Comparison of monopolar radiofrequency thermal ablation and conventional dissection tonsillectomy: a randomized control trial
Authors:   Department of Otorhinolaryngology and Head and Neck Surgery, Mahatma Gandhi Medical College and Research Institute, (A constituent college of Sri Balaji Vidyapeeth) SBV Campus, Pondicherry, India, Rasmika K. , Karthikeyan P. ,   Department of Otorhinolaryngology and Head and Neck Surgery, Mahatma Gandhi Medical College and Research Institute, (A constituent college of Sri Balaji Vidyapeeth) SBV Campus, Pondicherry, India, Govindarajan A. ,   Department of Otorhinolaryngology and Head and Neck Surgery, Mahatma Gandhi Medical College and Research Institute, (A constituent college of Sri Balaji Vidyapeeth) SBV Campus, Pondicherry, India
Published: August 2024

Aim: To compare monopolar radiofrequency thermal ablation with the conventional dissection tonsillectomy in terms of postoperative healing process and any possible complications. Methods: 56 patients of 14 years of age and above were randomly divided into two groups. Group 1 underwent Conventional dissection tonsillectomy and group 2 underwent Monopolar radiofrequency tonsillectomy. Intraoperative duration, bleeding, postoperative pain and healing were compared between the two groups. Intraoperative duration was measured and bleeding was analysed by visual estimation. Visual Analogue Scale was used to analyse the postoperative pain and a grading system was used to analyse healing. Objective: To compare monopolar radiofrequency thermal ablation with the conventional dissection tonsillectomy in terms of duration of surgery, perioperative blood loss and postoperative intensity of pain. Results: Intraoperative duration was found to be longer in RFA group with increased blood loss and p-value was found to be statistically significant of <0.001. Postoperative pain was found to be significantly low during postoperative day 0 and 1 with RFA group when compared to CD group with p-value <0.001. No statistically significant difference was noticed regarding the time taken for wound healing in both the groups. Conclusion: Conventional dissection tonsillectomy is better than monopolar radiofrequency ablation in terms of short operative duration and intraoperative bleeding even though monopolar radiofrequency ablation seems to be better than conventional dissection tonsillectomy in view of postoperative pain.
Current update on Chronic Rhinosinusitis
Authors:   Madras ENT Research Foundation, Chennai, India, Natarajan Kiran , Nandhan S. Raghu ,   Madras ENT Research Foundation, Chennai, India, Kameswaran Mohan ,   Madras ENT Research Foundation, Chennai, India
Published: August 2024

Chronic rhinosinusitis (CRS) is one of the commonest diseases in otorhinolaryngology and significantly affects thequality of life of patients. Traditionally, CRS has been divided into two phenotypes depending on the presenceor absence of nasal polyposis. Chronic type 2 inflammation is implicated in most cases of CRS. In recent years,increase in the understanding of the various disease entities of CRS has made endotyping of CRS an important toolin managing chronic rhinosinusitis. Newer concepts like super-antigens, enterotoxins, biofilms and fungal elementshave been implicated as the cause of refractory CRS. Evidence-based advancements in the medical and surgicalarmamentarium have resulted in improved treatment of CRS. In recalcitrant cases of CRS, biologics are being seenas an effective treatment modality. This article is a current update on the advances in understanding and managingchronic rhinosinusitis.
Videolaryngoscopy findings in laryngopharyngeal malignancies in Tertiary Cancer Care Centre – A descriptive study of Annual Data
Authors:   Government Kilpauk Medical College, Government Royapettah Hospital, Chennai, India, Arasan P. Thamizh
Published: August 2024

Aim: Our study was intended to analyze the videolaryngoscopy findings and find annual percentage prevalence ofcarcinoma larynx, hypopharynx, oropharynx and its sub-sites, also assessing its effectiveness for diagnosis and follow-up. Materials and methods: Patients who attended ENT OPD and diagnosed later with biopsy-proven carcinoma andpatients referred from the oncology department after chemo radiotherapy for follow-up from April 2023 to March2024 underwent videolaryngoscopy assessment. Results: A total of 132 patients underwent videolaryngoscopy, of whom 92 (69.7%) were male and 40 (30.3%)female. Carcinoma larynx cases were 54 (40.9%), out of which supraglottis 26 (48%), glottis 27 (50%), andsubglottis 1 (2%). Carcinoma hypopharynx cases were 61 (46.2%), out of which pyriform fossa 32 (52.5%),postcricoid 27 (44.3%), and posterior pharyngeal wall 2 (3.2%). There were 15 oropharynx (11.3%) and 2 (1.6%) other malignancy patients. 6 patients (4.5%) had two primary lesions. 25 patients (17.8%) had a T1 lesion, 48patients (34.3%) had a T2 lesion, 47 patients (33.6%) had a T3 lesion, and 20 patients (14.3%) had a T4 lesion. Theoverall purpose of videolaryngoscopy was diagnostic in 51 patients (38.6%) and follow-up after chemoradiotherapyin 81 patients (61.4%). Out of 41 diagnostic patients, (80.3%), a biopsy was done with videolaryngoscopy. In followupafter chemoradiotherapy, 37 out of 81 patients (45.7%) were asymptomatic without any recurrence or residuallesion. 44 out of 81 patients (54.3%) had symptomatic lesions and were advised further follow-up, radiologicalinvestigation, repeat biopsy, and radical surgery. Conclusion: Videolaryngoscopy is a simple outpatient efficacious investigation in the diagnosis follow-up ofpatients with laryngopharyngeal carcinoma.
Identification of mangrove damage and mangrove ecosystem management efforts in Ekasoghi Tourism, Saronggi District, Sumenep Regency
Authors: Maulidharta Syukron , Arisandi Apri , Farid Akhmad
Published: August 2024

The Saronggi District area, Tanjung Village has experienced changes in the structure of mangroves which resulted in a decrease in the number of mangroves due to mangrove tourism, lack of awareness of the importance of mangroves, and damage due to human activities. The purpose of this study is to find the causes of mangrove damage and formulate policies in the management of mangrove ecosystems in the Ekagoghi tourist area. This research was conducted with visual observation (descriptive narrative) and SWOT analysis to consider management policy strategies. The types of mangroves found on the coast of Ekasoghi in Sumenep Regency consist of species Osbornia octodonta, Sonneratia alba, Avicennia marina, Rhizophora mucronata, Lumnitzera racemosa, and Rhizopora apiculata which have been damaged by natural factors and human actions. The causes of mangrove damage include high beach abrasion so that beach erosion occurs and causes a reduction in nutrients and seaweed cultivation which causes damage to mangrove trees due to the charts used. Policies that need to be carried out for the management of mangrove ecosystems on Ekasoghi Beach, namely by holding wanamina cultivation (silvofishery) and the implementation of an ecopreneurship system, can be considered to develop policies directed to explore profit potential and maintain the sustainability of the existence of preserving mangrove ecosystems. This policy certainly needs to be supported by strengthening community institutions and cooperation between government institutions.
INDUSTRIAL ERGONOMICS: EXAMINING ERGONOMIC PRACTICES AND COMPUTER VISION SYNDROME (CVS)
Authors:   Department of Mechanical and Manufacturing, Faculty of Engineering, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia, Jamaluddin Jabar , Abd Rahman Nurul Izzah ,   Department of Mechanical and Manufacturing, Faculty of Engineering, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia, Ahmad Siti Azfanizam ,   Department of Mechanical and Manufacturing, Faculty of Engineering, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
Published: August 2024

Computers have become a major component in daily life, especially in the context of higher education in this digital age. University lecturers increasingly rely on computers to perform various daily tasks, which is a trend that has intensified particularly in the wake of the Covid-19 pandemic. The growing dependence on computers raises concerns about the negative health implications that may arise from long-term use. One of the main effects is Computer Vision Syndrome (CSV). CSV is a result of continuous computer use and can have a negative impact on eye health. One strategy to address this issue is to implement ergonomic principles when using computers. This study aims to investigate ergonomic practices among university lecturers, as well as the prevalence of CSV among them. In addition, this study aims to determine the relationship between CVS and ergonomics. This study involves data collection through questionnaires which the respondents are university lecturers in Malaysia. A total of 245 randomly selected respondents answered the questionnaire distributed through an online platform. The data obtained was analyzed using descriptive and Chi Square analysis, exploring ergonomic practices such as eye distance from the screen, viewing angle, keyboard position, light intensity, position of neck, head, wrist, thigh position and stretching practices. According to the study's findings, over 56% of lecturers incorporate ergonomic principles when using computers; nevertheless, only 38.4% of respondents adhere to the recommendation for keyboard viewing distance. Next, the CVS symptoms are categorized into three, namely eyes, vision and head, neck, and shoulders. A comparison between these three categories of symptoms showed that the head, neck, and shoulders symptoms were the most significant with 42.1% of the respondents showing moderate and severe symptoms. It is followed by vision and finally symptoms to the eyes, with the percentage of 22.9% and 19.6%, respectively. In addition, it was found that one vision symptom is associated to monitor distance (p 0.05). The findings from this research contributed valuable insights into understanding the occupational risks associated with prolonged computer use in academic settings. By raising awareness and potentially implementing preventative measures, this study helps to promote better well-being among university lecturers.
CRITICAL ROLES IN BALANCING CUSTOMER EXPECTATIONS AND SOFTWARE PRODUCT DEVELOPMENT: A BUSINESS PERSPECTIVE
Authors:   ”Gheorghe Asachi” Technical University of Iasi-Romania, Department of Engeeninring and Management, Blvd. Mangeron, No. 28, 700050, Iasi, Romania, Lucescu Letiția , Bagiu Neculai ,   ”Gheorghe Asachi” Technical University of Iasi-Romania, Department of Engeeninring and Management, Blvd. Mangeron, No. 28, 700050, Iasi, Romania
Published: August 2024

In the quest for organisational agility in product development, critical roles emerge as vital connectors between client expectations and organisational capabilities. This paper explores the dynamic interplay of roles like product owners, innovation champions, and cross-functional teams in aligning innovation, technology, and people to meet customer demands. These roles serve as vital connectors, bridging the gap between customer expectations and product development constraints. Within the context of business agility and Agile methodologies, they orchestrate a harmonious balance that fuels innovation, enhances customer satisfaction, and ensures success in today's rapidly evolving business landscape. By fostering a culture of adaptability and collaboration, by fostering a culture of adaptability, collaboration, and responsiveness, organisations can enhance their ability to satisfy customers' evolving needs while ensuring the efficient execution of product development processes.
Production of PRRSV-negative pigs commingled from multiple, vaccinated, serologically stable, PRRSV-positive breeding herds
Authors: Raji Andrijana , Dewey Catherine , Deckert Anne , Friendship Robert , Martin Wayne , Yoo Dongwan
Published: August 2024

Objectives: To determine whether PRRSV-negative pigs could be produced from multiple PRRSV-positive herds and to investigate the serological stability of these herds and the impact of sow vaccination. Methods: Piglets originating from non-vaccinated and vaccinated herds were weaned at 8 to 14 days and housed separately in an off-site nursery for 90 days. Pigs were tested by PRRS IDEXX ELISA at weaning and at 30, 60, and 90 days of age. A subset of pigs was tested using PRRS reverse transcription-polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP) assays. Serological stability of breeding herds was assessed by PRRS IDEXX ELISA. Results: The five vaccinated herds were serologically stable. Piglets from these herds became seronegative after weaning and remained PRRSV negative up to 90 days of age. Pigs from two of the five non-vaccinated herds were PRRSV negative. One of these herds was serologically stable. Piglets from the other three non-vaccinated herds were PRRSV positive at weaning, and the number of seropositive piglets and their S:P values increased to 90 days of age. Two of these herds were not serologically stable. After vaccination of open sows and gilts, PRRSV-negative pigs were produced from one of these two herds. Implications: Piglets weaned at 8 to 14 days from multiple, serologically stable sow herds and commingled were PRRSV negative at 90 days of age. Vaccinating gilts twice prior to breeding and sows at weaning may increase the stability of breeding herds. Results must be validated in large commercial operations.
Porcine proliferative enteropathy: a case-control study in swine herds in the United States
Authors: Bane David , Neumann Eric , Gebhart Connie , Gardner Ian , Norby Bo
Published: August 2024

Objective: To describe epidemiologic characteristics of outbreaks of porcine proliferative enteropathy (PPE) and evaluate associations between herd production and management factors, and disease occurrence. Methods: A questionnaire about management factors was administered by telephone to the owners or managers of 30 PPE-affected herds (cases) and 18 unaffected herds (controls). Morbidity, mortality, and demographics of animals in affected herds were recorded. Fecal samples from approximately six pigs in each herd were tested by polymerase chain reaction (PCR) for Lawsonia intracellularis. Results: Porcine hemorrhagic enteropathy (PHE) occurred in 11 herds, and porcine intestinal adenomatosis (PIA) in 19 herds. In multivariable logistic regression analysis, use of a new building and recent mixing of pigs were associated (P<.05) with PPE. Management stressors such as overheating, chilling, number of times mixed, number of feeders per pen, and group size were not significantly associated with PPE. Fecal samples were more likely (P<.05) to be positive by PCR in case than control herds. Herds with PHE were more likely (P=.05) than herds with PIA to have at least one PCR-positive fecal sample. Implications: Placement of pigs into new facilities and commingling of groups of pigs significantly increase the risk of PPE. Production and management practices linked with high health status may not be associated with reduced risks of PPE outbreaks. Analysis of fecal samples by PCR is useful to detect L intracellularis in the population, but fecal samples are more likely to be PCR positive in herds with PHE than in herds with PIA.
Comparative Security and Compliance Analysis of Serverless Computing Platforms: AWS Lambda, Azure Functions, and Google Cloud Functions
Authors: Khanal Dibya Darshan , Maharjan Sushil
Published: August 2024

Serverless computing has revolutionized cloud services by abstracting infrastructure management, enabling developers to focus on application logic. This research examines the security and compliance features of three major serverless platforms: AWS Lambda, Azure Functions, and Google Cloud Functions. By evaluating authentication mechanisms, data encryption practices, vulnerability management, and compliance certifications, we aim to provide a comparative analysis that informs businesses and developers on the most secure and compliant platform for their needs. Keywords: Serverless Computing, Security, Compliance, AWS Lambda, Azure Functions, Google Cloud Functions, Cloud Security Alliance, Cloud Controls Matrix
Understanding Bitcoin and Blockchain
Authors: Sugurushetty Shivani
Published: August 2024

Blockchain is the technology that enables the existence of cryptocurrency. Bitcoin is the name of the most recognized cryptocurrency, the one for which blockchain technology, as we currently know it, was created. A cryptocurrency is a medium of exchange such as the US dollar, but is digital and uses cryptographic techniques and its protocol to verify the transfer offunds and control the creation of monetary units. Keywords: crypto, digital currency, blockchain, bitcoin.
Uncertainty Analysis of Tensile Strength of Scarf Adhesive Joints Using Numerical Method
Authors:   Department of Mechanical Engineering & SKN Sinhgad College of Engineering, Korti,Pandharpur., Sawant B. P , Kulkarni P. P ,   Department of Mechanical Engineering & SKN Sinhgad College of Engineering, Korti,Pandharpur.
Published: August 2024

This study uses three-dimensional finite element (FE) analysis to investigate stress distribution and fatigue strength in adhesive scarf joints, which are complex due to their oblique geometry and varying material properties. ANSYS was used to model stress components within the adhesive and at the adhesive-adherent interface. The FE models, created with eight-node solid elements, utilized fine meshing to ensure accurate stress representation. A mesh size of 0.025 mm was optimal. The models, assuming linearly elastic materials, were validated by comparing simulated deformations with experimental results. Findings enhance understanding of local stress states, improving adhesive joint design reliability. Key Words: Adhesive scarf joints, finite element analysis, stress distribution, fatigue strength, ANSYS,
Refining Credit Risk Analysis- Integrating Bayesian MCMC with Hamiltonian Monte Carlo
Authors: Apte Mohit
Published: August 2024

The accurate prediction of loan defaults is paramount for financial institutions to enhance decision-making processes, optimize loan approval rates, and mitigate associated risks. This study develops a predictive model utilizing Bayesian Markov Chain Monte Carlo (MCMC) techniques to forecast potential loan defaults. Employing a comprehensive dataset of 255,000 borrower profiles, which include detailed borrower characteristics and loan information, the model integrates advanced statistical methods to assess and interpret the factors influencing loan defaults. The Bayesian framework allows for robust uncertainty quantification and model complexity management, making it particularly suitable for the nuanced nature of credit risk assessment. Results from the model demonstrate a compelling accuracy rate, substantially aligning with industry benchmarks while providing deeper insights into the probability of default as influenced by various borrower attributes. This research underscores the efficacy of Bayesian MCMC modelling in financial risk management and offers a scalable approach for financial institutions aiming to refine their credit evaluation strategies.
Exploring Anomaly Detection and Risk Assessment in Financial Markets Using Deep Neural Networks
Authors: Wang Bingxing , Dong Yuxin , Yao Jianhua , Qin Honglin , Wang Jiajing
Published: August 2024

In this paper, deep learning technology, along with a Gated Recurrent Unit (GRU) combined with an attention mechanism, is used to enhance the recognition ability and risk assessment accuracy of abnormal trading behavior in financial markets. The GRU effectively solves the problem of gradient vanishing in traditional recurrent neural networks through its unique gated structure, allowing the model to learn more stable and effective feature representations in long sequence data. On this basis, the contextual attention (CA) module in the attention mechanism is introduced, enabling the model to automatically learn and assign different weights to various parts of the input sequence. Combined with bidirectional GRU and the attention mechanism, the model can not only capture temporal dependencies in the sequence, but also highlight the key features that affect market anomalies, thus improving the model's ability to understand complex market dynamics.
Human Rights Violation of Dalit Women in Bangladesh
Authors: Fariha Tasnim Nowshin
Published: August 2024

By reviewing secondary literature, this paper has analyzed the human rights situation and challenges of Dalit communities in Bangladesh, with a specific focus on the status of their women. The review unravels that Dalits belong to the most underprivileged minor communities, generally considered as lesser human beings, impure, polluted, and are secluded as well as excluded from the social and economic domains of mainstream society. Due to the social norms associated with caste system, their economic opportunities are strictly limited to menial, low paid, and service oriented jobs. Social exclusion denies their access to most basic rights, opportunities, and potential to develop as full human beings. As a result, they fail to break the inter-generational cycle of poverty, exclusion, and other forms of socio-economic marginalization. Dalit women’s situation is far worse and daunting due to their multifaceted marginal identities of being gender, religious, and occupational minorities. Finally, this paper advocates the necessity for hearing the voices and perspectives of Dalit communities, and facilitate social dialogues between them and stakeholders from governmental and non-governmental organizations, to preserve and re-conceptualize Dalit’s human rights in their own terms.
MANAGEMENT OF NON-SPECIFIC ORBITAL INFLAMMATION USING HARIDRADI BIDALAKA- A CASE REPORT.
Authors: A. P. Gorakh , Dakhore J
Published: August 2024

Idiopathic orbital inflammatory disease (IOID), also called non-specific orbital inflammation (NSOI) or orbital pseudotumor, is an uncommon disorder characterized by nonneoplastic, non- infective, space-occupying orbital infiltration with inflammatory features. The process may preferentially involve any or all of the orbital soft tissues. Histopathological analysis reveals pleomorphic inflammatory cellular infiltration followed by reactive fibrosis. Unilateral disease is typical in adults, although in children bilateral involvement may occur. Intracranial extension is rare. Simultaneous orbital and sinus involvement is also rare and may be a distinct entity [1]. According to Ayurveda, this inflammatory condition on the eye lids can be correlated with Kaphaja Netra Abhishyanda and treated accordingly. Kaphaja Netra Abhishyanda is defined in Ayurveda as a disease affecting all parts of the eye characterised by Guruta (heaviness of lids), Kandu (itching), Pichila (repeated lacrimation), Alpa Vedana (Foreign body sensation) photophobia and burning sensation in eyes etc. An ocular therapeutic called Bidalaka is the application of medicated paste on the eye's outer surface expect eye lashes. Bidalaka is indicated in inflammatory conditions of the eyes. A 72-year-old female patient diagnosed with NSOI on clinical presentation was advised Haridradi Bidalaka for five days. The signs & symptoms were reduced to a very mild degree. The result proved to be effective based on clinical assessment.
JALAUKAAVACHARANA ASSISTED TREATMENT OF SCALP PSORIASIS (KITIBHA KUSHTHA) - A CASE STUDY
Authors: Patil R  , Patki G  , Prabhu M  , Bapat A
Published: August 2024

Kushtha is one of the Raktavaha srotas vyadhi explained in Ayurvedic literature. Scalp psoriasis (kitibha kushtha) is a chronic autoimmune disease (caused by ones’ own immune system) that causes skin cells to reproduce too quickly. It is one of the mahagadas, having chirkaalin utpatti, sthiti and laya. It is tridosha pradhan disease with dominance of kapha dosha is crucial. Kushtha is one of dushta karma, doshajanya vyadhi, and is one of the chronic diseases that takes longer time to get cured. In this case study, A 43-year-old male came to OPD with the complains of Shiro Kandu (itching on scalp), Kesha Patan (hair fall), Darunaka (Dandruff) for about a year and was diagnosed with scalp psoriasis. Patient developed small black skin lesion on frontal region of scalp with severe itching and roughness at same place. Jalaukaavacharana and internal medicines such as Kanchana rasayana, Pachaka churna, arogyavardhini Gandhaka rasayan, Krimikuthar rasa, along with external medication including Fungiwin cream, Udwartana with lodhra and amlaki powder were prescribed. Suitable ahar and vihar were prescribed to the patient to support faster recovery. Results showed that Jalaukaavacharana, internal medicines along with dietary and lifestyle modification remarkedly and completely cured kitibha kushtha in 75 days without the need of hospitalisation.