bluuebunny/crossref_metadata_2025 huggingface dataset:
Flexural behaviour of lightweight aggregate concrete columns
Authors: Yang Keun-Hyeok , Mun Ju-Hyun , Im Chae-Rim
Published: February 2022

The flexural performance of lightweight concrete (LWC) columns was evaluated and limitations of ACI 318-19 in predicting the flexural crack (Mcr) and maximum (Mn) moments, as well as the minimum amount of transverse reinforcing bar (Ash(ACI)), were examined. Six LWC columns with different amounts of transverse reinforcing bar (Ash), compressive strengths of concrete (fc′) and concrete types were prepared and tested under constant axial and cyclic lateral loads. The test results show that ACI 318-19 agrees well with the Mcrof tested columns, considering the lower tensile stress of LWC columns by introducing modification factors (λ) (all-lightweight concrete, λ = 0.75; sand–lightweight concrete, λ = 0.85) for the fracture modulus of concrete (fr). In addition, ACI 318-19 underestimates Mn, irrespective of Ash, fc′ and concrete type. The ductility of LWC columns increased with the increase in volumetric transverse reinforcing bar index (ωvh). The increasing rate was lower than that of normal-weight concrete (NWC) columns. The displacement ductility ratio (μΔ), work damage indicator (W80) and equivalent damping coefficient (ξ80) of a column with 1.0Ash(ACI)were, on average, 30, 36 and 18% lower in LWC than NWC columns. Consequently, double the Ash(ACI)was required to retain a flexural ductility equivalent to that of a NWC specimen.
„Einheitliche Regelungen in der Deutschen Rentenversicherung sind extrem wichtig“ (Interview)
Authors: Kindel Jutta
Published: February 2022

Frau Dr. med. Nathalie Glaser-Möller, Leiterin der Stabsstelle Reha-Strategie, -Grundsatz und -Steuerung der Deutschen Rentenversicherung Nord mit Sitz in Lübeck, wurde am 1. September 2021 in den Ruhestand verabschiedet. Sie spricht über ihre Tätigkeit und die Schwerpunkte ihrer Arbeit mit besonderem Blick auf aktuelle Herausforderungen. Das Gespräch führte Jutta Kindel.
Rejtőzködő hungarikumok a Bibliothèque Nationale de France kézirattárában
Authors: Tóth Ferenc
Published: February 2022

A Bibliothèque Nationale de France Kézirattára az egyik legjelentősebb francia központi archívum. A kézirattárban számos kiemelkedően fontos magyar vonatkozású forrás található, de szintén jelentős számban lelhetünk itt olyan „rejtőzködő” magyar vonatkozású munkát, amelyek a kéziratok beosztásának köszönhetően eddig elkerülték a kutatók figyelmét. A tanulmány egy ilyen forráscsoportban, a török nyelvű kéziratokban található, a 18. századi konstantinápolyi École des jeunes de langues hallgatóinak tollából származó fordítások között folytatott kutatások magyar vonatkozású eredményeit szeretné megosztani az olvasókkal. A magyarorszá török háborúk több oszmán krónikájának fordításán kívül Ibrahim Müteferrika magyar származású oszmán hivatalnok és diplomata által működtetett nyomda szinte valamennyi művének francia nyelvű változata is megtalálható. Az könyvészeti és levéltári források összehasonlításával a tanulmány rámutat II. Rákóczi Ferenc vezettte szabadságharc bukása utáni magyar emigráció kultúraközvetítő szerepére is.
ПРИНЦИПЫ ОБЯЗАТЕЛЬНОЙ ГЕНОМНОЙ РЕГИСТРАЦИИ ОСУЖДЕННЫХ
Authors:   Томский государственный университет, Ольховик Николай Владимирович
Published: February 2022

Анализируются принципы обязательной геномной регистрации осужденных. Принципы обязательной геномной регистрации осужденных к лишению свободы включают в себя не только принципы, указанные в ст. 3 ФЗ № 242-ФЗ «О государственной геномной регистрации в Российской Федерации», но и основополагающие начала медико-санитарного обеспечения осужденных к лишению свободы, а также принципы обработки персональных данных, которые определяются Федеральным законом от 27.07.2006 № 152-ФЗ «О персональных данных». Сформулированы определения принципа законности, принципа гуманизма, принципа конфиденциальности обязательной геномной регистрации осужденных.
ПЕРСПЕКТИВЫ РАЗВИТИЯ РОССИЙСКОГО ЗАКОНОДАТЕЛЬСТВА В СФЕРЕ ПРАВОВОГО РЕГУЛИРОВАНИЯ НАУЧНЫХ ИССЛЕДОВАНИЙ С ИСПОЛЬЗОВАНИЕМ БИОЛОГИЧЕСКИХ ОБРАЗЦОВ ЧЕЛОВЕЧЕСКОГО ПРОИСХОЖДЕНИЯ
Authors:   Томский государственный университет, Болтанова Елена Сергеевна , Имекова Мария Павловна ,   Томский государственный университет
Published: February 2022

В странах Европейского союза существует тенденция нормативного обеспечения охраны прав граждан при проведении научных исследований с использованием биологических образцов человеческого происхождения. В России такая охрана прав граждан обеспечивается исключительно при предупреждении, раскрытии и расследовании преступлений. Авторы статьи по аналогии с законодательством Европейского союза предлагают принять новый Федеральный закон «Об исследованиях биологических образцов человеческого происхождения».
ГЕНОМНЫЕ ИССЛЕДОВАНИЯ, ПРАВО И ПРАВА ЧЕЛОВЕКА
Authors:   Хмельницкий университет управления имени Леонида Юзькова, Бориславская Марина Вячеславовна
Published: February 2022

Статья посвящена анализу влияния геномных исследований на современный мир. Исследуется вопрос о соотношении прав отдельного человека, прав общества и будущих поколений, связанных с проведением геномных исследований. Установлено, что на сегодняшний день не существует адекватных механизмов защиты человека и его будущих поколений от возможных негативных и опасных способов использования результатов геномных исследований.
[RETRACTED] Staminon Male Enhancement - Reviews – Effective Pills That Work or Cheap Scam? [United States] v1
Authors: Male Enhancement Staminon
Published: February 2022

[RETRACTED]

Staminon Male Enhancement - Reviews – Effective Pills That Work or Cheap Scam? [United States]
[RETRACTED] Staminon Male Enhancement Scam Features Clint Eastwood and Dr. Phil v1
Authors: Los Car
Published: February 2022

[RETRACTED]

https://www.crunchbase.com/event/staminon-male-enhancement
[RETRACTED] Ultra Keto White Reviews - Does Ultra White Keto BHB Pills Works? v1
Authors: not provided ultrawhitereviews
Published: February 2022

[RETRACTED]

Ultra Keto White Reviews - Does Ultra White Keto BHB Pills Works?
Relational Urbanisation, Resilience, Revolution: Beirut as a Relational City?
Authors: Rafferty Michael
Published: February 2022

The destruction of Beirut’s port and large areas of the inner city following the August 2020 explosion occurred amid (and has exacerbated) an unprecedented national economic and social crisis portending another potential phase of urban “reconstruction” and a national political revolution. Critical scholars have highlighted the shortcomings of urban planning and governance in the city after the Lebanese civil war, particularly in terms of housing, infrastructure, and social inequalities, especially between the urban core and periphery. Beirut’s post-war reconstruction(s), guided by blended-scale governance (i.e., public/private, confessional/political, national/local) and a real estate-oriented growth model have neither managed to completely restore nor efface the city’s erstwhile status as an entrepôt of regional and international economic, cultural, and political importance but have instigated processes of rapid urbanisation and uneven development. These processes, historical trajectories, political and socio-economic dialectics, and shifts in urban political economy render Beirut relevant to the nascent empirical category of “relational cities,” i.e., cities whose geographical-historical profiles position them as urban nodes connecting regional-global-national systems of flows under globalised capitalism. This article positions Beirut in the context of the debate on relational urbanisation for empirical exploration, and also points to the evental possibilities for alternative geographies that flow from the October 2019 protests.
Visibilizando lo oculto. Reconstrucción digital y análisis espacial del registro geoarqueológico del Pleistoceno superior del LIG del abrigo rocoso de Jarama VI en el cañón del Jarama (Valdesotos, Guadalajara, España)
Authors: Jordá Pardo Jesús F. , Salido Juana Molina , Maximiano Castillejo Alfredo M. , Barcia García Camilo , Acevedo Pardo Carlos , Alonso Miriam , Álvarez-Alonso David , Díez Fernández-Lomana Juan Carlos , Díez-Herrero Andrés , Farjas Mercedes , Garrote Julio , Hernández Orgaz Arturo , Hernández Ruiz Mario , Kehl Martin , Romero Antonio Jesús , Moya Yolanda Sánchez , Schramm Tomas , Sopeña Ortega Alfonso
Published: February 2022

El Lugar de Interés Geológico de Jarama VI es un abrigo rocoso que contiene una secuencia litoestratigráfica formada por cinco unidades sedimentarias del Pleistoceno superior, tres de las cuales presentan restos arqueológicos del Paleolítico medio con una edad mayor de 50 ka BP. En una de ellas se ha recuperado un resto óseo de Homo neanderthalensis. Para preservar toda la información analógica disponible sobre este LIG y contar con un registro digital del mismo, hemos llevado a cabo tres proyectos consecutivos cuyos objetivos se centraron en la obtención de una cartografía digital de detalle del yacimiento y su entorno, la digitalización del registro arqueológico analógico de las excavaciones realizadas entre 1989-1993, la creación y cumplimentación de una Infraestructura de Datos Espaciales y la realización de un análisis microespacial y estadístico del yacimiento, a la vez que hemos llevado a cabo un estudio hidráulico de las paleoinundaciones observadas en su registro sedimentario.
Características geoquímicas y micropaleontológicas de las marismas en el Estero de Urías, Golfo de California, México
Authors: Cearreta Alejandro , Machain-Castillo María Luisa , Ruíz-Fernández Ana Carolina , Sánchez-Cabeza Joan-Albert , Serrato-De la Peña Jorge Luis , Flores-Verdugo Francisco , Pérez-Bernal Libia Hascibe
Published: February 2022

Se analizaron la composición elemental de los sedimentos y la distribución y abundancia de microfósiles en dos zonas de marisma de la laguna costera Estero de Urías (Golfo de California, México) con el fin de determinar las características ambientales de este medio marino restringido. En los sedimentos se detectó un enriquecimiento por metales (en particular Cu, Ni, Pb y Zn) probablemente debido a la combustión de carburantes relacionada con las actividades del puerto y la estación termoeléctrica aledaña a la laguna. Los foraminíferos bentónicos y los ostrácodos mostraron una relación con la elevación topográfica sobre el nivel marino medio, con muy pocas especies constituyendo las asociaciones. No se observó una relación entre la contaminación de los sedimentos y la presencia o abundancia de individuos y caparazones en las muestras. Este enfoque combinado entre geoquímica y micropaleontología se considera adecuado para la identificación de posibles impactos humanos y variaciones en el nivel del mar a partir de secuencias sedimentarias históricas y holocenas en esta región costera.
El yacimiento musteriense de Roca San Miguel (Arén, Prepirineo de Huesca)
Authors: Montes Ramírez Lourdes , Domingo Rafael , Sampietro-Vattuone Maria Marta , Medialdea Alicia , Peña Monné José Luis
Published: February 2022

El yacimiento musteriense de Roca San Miguel se sitúa en el curso alto del río Noguera Ribagorzana, en el Prepirineo de Huesca. Aunque en la actualidad se extiende por una ladera con la apariencia de un sitio al aire libre, un resalte de arenisca hoy erosionado debió generar un abrigo rocoso que prestaría protección a sus ocupantes prehistóricos. Se han realizado 3 catas arqueológicas, de las que la intermedia y superior son las que aportan hasta el momento la información más relevante. En la excavación se han diferenciado 5 Unidades estratigráficas compuestas por diferentes niveles arqueológicos que han sido datados por Luminiscencia Ópticamente Estimulada (OSL). Las dataciones de la Unidad A, con abundantes restos de hogares, la sitúan cronológicamente en el Penúltimo Periodo Glacial (PGP) en unas condiciones paleoambientales de frío extremo. La Unidad B todavía no ha sido excavada. La Unidad C abarca desde el final del Eemiense hasta el MIS 5d en el Último Periodo Glacial (LGP), con abundantes restos líticos y de fauna. La Unidad D incorpora materiales desplazados por la ladera superior, indicando el abandono del yacimiento, datado en 81,2±4,7 ka. Por último, la Unidad E recubrió el lugar durante MIS 2, cuando el sitio estaba ya parcialmente erosionado. La datación con OSL de la terraza Qt5, situada en el entorno del yacimiento, permite además relacionarlo con el sistema de terrazas de la cuenca fluvial Segre-Cinca y las fases glaciales de su cabecera. Con todo ello, se crea un modelo evolutivo que abarca desde MIS 6d hasta el MIS 5a (Último Periodo Glacial), pudiendo afirmar a partir de su depurada cronología que actualmente es el yacimiento con las ocupaciones neandertales más antiguas del Prepirineo.
Contexto crono-estratigráfico y cultural del conjunto lítico de Base Menacho (cuenca del río Guadiana, Badajoz, España): primeros resultados
Authors: García-Vadillo Francisco Javier , Duval Mathieu , Canals-Salomó Antoni , Rodríguez-Álvarez Xosé-Pedro , Garriga Joan Garcia , Carbonell-Roura Eudald
Published: February 2022

En este trabajo presentamos el conjunto lítico de Base Menacho (Badajoz, España), documentado en un nivel sedimentario que cubre los depósitos aluviales de la terraza fluvial T3 +10-20 m sobre el cauce actual del río Zapatón, subafluente del río Guadiana en el sector de las Vegas Bajas (Badajoz, España). El conjunto se compone de 46 elementos líticos incluyendo lascas, núcleos y configurados. No se han identificado elementos líticos característicos que permitan una atribución firme a los tecnocomplejos de Modo 2 o 3. Ya que los elementos líticos fueron documentados en arenas finas y no muestran evidencias aparentes de marcas de abrasión, asumimos de forma preliminar la ausencia de transporte (o muy limitado). Estas observaciones sugieren que el conjunto se encuentra en posición primaria. La datación por Resonancia Paramagnética Electrónica (ESR) de una muestra de cuarzo procedente del nivel arqueológico proporciona una edad del enterramiento de 19,2 ± 1,7 ka (1σ). Teniendo en cuenta todas las fuentes de incertidumbre relativas al resultado, esta datación numérica permite: 1) correlacionar a Base Menacho con el Pleistoceno superior final y en particular con el estadio isotópico (MIS) 2; 2) establecer indirectamente la cronología de una industria lítica cuyas características poco resolutivas son similares a otros conjuntos relativamente poco estudiados documentados en contextos fluviales de la Península Ibérica; y 3) situar a Base Menacho en el Paleolítico superior, un período con escasas evidencias arqueológicas en el interior de la Península Ibérica. Aunque estos resultados preliminares prometedores demuestran el potencial interesante del conjunto lítico de Base Menacho, reconocemos también la necesidad de realizar una excavación arqueológica en un futuro próximo, para aumentar el tamaño del conjunto y obtener una mejor comprensión de su variabilidad y de los procesos de formación del yacimiento.
Sistema de visión estereoscópica para la detección de obstáculos en tiempo real con sistemas empotrados de bajo coste
Authors: Gilabert Gisbert Miguel , Masiá Vañó Jaime , Micó Tormos Pau
Published: February 2022

En este documento se pretende mostrar el análisis para el desarrollo de una aplicación de visión estereoscópica destinada a proporcionar autonomía en sistemas robotizados, utilizando sistemas empotrados de bajo coste. Se procederá a analizar información en tiempo real, obtenida mediante dos cámaras de forma simultánea, reconstruyendo la escena 3D y representando la profundidad de los objetos detectados.
Control visual dinámico basado en FPGA de un robot manipulador de 6 grados de libertad
Authors: Alabdo Aiman , Pérez Javier , Pomares Jorge , García Gabriel J. , Torres Fernando
Published: February 2022

En este artículo se describe la formulación, implementación y experimentación de un sistema de control visual dinámico aplicado a un robot de 6 grados de libertad. Se propone una arquitectura hardware basada en FPGAs para la implementación de los controladores. Con el objetivo de limitar la latencia del controlador se ha implementado en la FPGA no sólo el controlador sino también la captura y procesamiento de la información visual. Se hace uso de las capacidades de procesamiento paralelo de la FPGA para optimizar los diferentes componentes del sistema de control visual propuesto. Finaliza el artículo con los resultados experimentales obtenidos en tareas de posicionamiento de un robot Mitsubishi PA10 de 6 grados de libertad.
Planificación multinúcleo en sistemas particionados
Authors: Brocal Vicent , Crespo Alfons , Balbastre Patricia
Published: February 2022

Actualmente, las aplicaciones embebidas se consideran de complejidad creciente y, como consecuencia, de mayor dificultad para su desarrollo y validación. Debido a estas características, existe un gran interés en ejecutar múltiples aplicaciones sobre una única plataforma (mono o multinúcleo). En los sistemas de tiempo real, cada vez más se ejecutan aplicaciones con diferentes niveles de criticidad donde múltiples componentes con diferentes restricciones de tiempo real se integran en una misma plataforma computacional. Al mismo tiempo en el que proliferan los sistemas de criticidad mixta, la plataforma computacional está migrando de mono núcleo a multinúcleo. El presente trabajo describe la planificación de sistemas particionados multinúcleo, desde la asignación de tareas a núcleos hasta la generación de la planificación para cada procesador.
Accuracy analysis of marker-based 3D visual localization
Authors: López-Cerón Alberto , Cañas José M.
Published: February 2022

3D localization from images is an useful capability for robots and cameras. One successful approach is to rely on visual SLAM techniques. Another approach, maybe more robust, is to use visual markers in the environment. In this paper a study about the accuracy of marker based visual 3D localization is presented, using AprilTags markers and the solvepnp algorithm in OpenCV library. The impact of distance to markers, number of markers, their position in the image on accuracy of the 3D estimated pose is experimentally measured and analyzed.
Objects positioning in water surface from a single image
Authors: Romeo Juan , Aranda Joaquín , Pajares Gonzalo , de la Cruz Jesús Manuel
Published: February 2022

Boats positioning is an important task required for autonomous navigation and control. This paper proposes a new method for estimating real positions (x-y coordinates) of small boats in the 3D scene from a single image. These positions are obtained with respect to a world reference system by the only means of using rows and columns of pixels where the boat is located in the image. A single camera is needed without requiring knowledge of its intrinsic and extrinsic parameters. The proposed approach avoids the use of more complex and sophisticated systems such as GPS. The method is valid for any object on a planar surface with the only constraint that the camera must be on a fixed position. It has been proven with a differential GPS of high precision. The main contribution is made on the computation of both x and y coordinates from a reference system. This method is also valid for objects in other planar surfaces, such as flat fields, crops, indoor floors or horizontal roads.
A ROS reactive navigation system for ground vehicles based on tp-space transformations
Authors: Rodríguez Enrique , Blanco José Luis , Torres José Luis , Moreno Jose Carlos , Giménez Antonio , Guzmán José Luis
Published: February 2022

This work focuses on the analysis and bench- marking of the mrpt_navigation ROS package. The package includes a reactive navigation method based on Trajectory Parameter Space (TP-Space) transformations, together with other nodes such as an alternative particle-filter localization system. A description of its structure and methods in which it is based will be performed. To validate the suitability of the package, tests are performed with a mobile robot with strong kinematic constraints (Ack- erman steering) and the result will be compared with the navigation ROS package, a standard for robots autonomous navigation.
Detección de lugares con cámaras RGB-D. Aplicación a cierre de bucles en SLAM
Authors: Zúñiga-Nöel David , Ruiz-Sarmiento José-Raúl , Gonzalez-Jimenez Javier
Published: February 2022

En este trabajo se propone un método que combina descriptores de imágenes de intensidad y de profundidad para detectar de manera robusta el problema de cierre de bucle en SLAM. La robustez del método, proporcionada por el empleo conjunto de información de diversa naturaleza, permite detectar lugares revisitados en situaciones donde métodos basados solo en intensidad o en profundidad presentan dificultades (e.g. condiciones de iluminación deficientes, o falta de geometría). Además, se ha diseñado el método teniendo en cuenta su eficiencia, recurriendo para ello al detector FAST para extraer las características de las observaciones y al descriptor binario BRIEF. La detección de bucle se completa con una Bolsa de Palabras binarias. El rendimiento del método propuesto se ha evaluado en condiciones reales, obteniéndose resultados muy satisfactorios.
Radioembolization for hepatocellular carcinoma: what clinicians need to know
Authors: Choi Jin Woo , Kim Hyo-Cheol
Published: February 2022

Transarterial radioembolization (TARE) with yttrium 90 (90Y) has been used in the management of hepatocellular carcinoma (HCC) for more than 10 years in Korea. There are two types of 90Y radioactive microspheres available, namely, glass and resin microspheres, with comparable clinical outcomes. In general, TARE outperforms transarterial chemoembolization regarding post-embolization syndrome, time to progression, tumor downsizing for liver transplantation, and hospitalization stay. Although TARE is commonly recommended for patients with unresectable large HCCs, it can be an alternative to or performed in combination with ablation, surgical resection, and systemic treatment. This review aimed to address 90Y radioactive microspheres, patient selection, clinical outcomes, simulation tests, radioembolization procedures, follow-up imaging, and complications.
Fatores Intervenientes de Resultados no Ensino Remoto: O Dispositivo de Acesso Importa?
Authors: Braga Daniel Santos , Brescia Amanda Tolomelli
Published: February 2022

Este artigo analisa resultados educacionais e avaliativos do ensino remoto em relação ao tipo de dispositivo eletrônico utilizado para assistir às aulas e para resolução de atividades, bem como a forma de se assistir às aulas (síncrona ou assíncrona, velocidade normal ou velocidade aumentada). Foram investigados estudantes de três turmas de dois cursos de formação de professores de uma instituição de ensino superior pública de Minas Gerais. A partir de questionário autoaplicado, foi realizado cotejamento estatístico de resultados educacionais pelo tipo de dispositivo eletrônico utilizado e a forma de se assistir às aulas, controlado pela presença ou ausência de ingresso por cotas (tomadas como proxy de nível socioeconômico). Foi possível evidenciar que, para a amostra, não houve diferença estatística significativa entre notas de estudantes que assistiram às aulas em computadores de mesa e notebooks, mas essa diferença ocorre quanto ao uso de dispositivos para a realização de atividades. Também houve diferença entre as notas dos que assistiram às aulas de maneira síncrona ou assíncrona, mas essa diferença não é percebida entre os que assistiram aulas gravadas em velocidade normal ou aumentada. Sendo assim, foi possível estabelecer admissibilidade de maior adequação para o uso de dispositivos como computadores de mesa e notebooks, e o acompanhamento síncrono das aulas. Houve tendência de melhor resultado para essa situação em relação à utilização de smartphones e tablets, e do acompanhamento de aulas assincronamente.
Palavras-chave: Ensino remoto. Tecnologias digitais. Avaliação da educação. Resultados educacionais. Ensino superior.
Museus Virtuais: o Museu da Pessoa na Construção do Conhecimento Histórico e Geográfico pela Criança em Tempos de Pandemia de Covid-19
Authors: Costa Junior Waldemir Rodrigues , Thomé Zeina Rebouças Corrêa
Published: February 2022

O objetivo principal deste trabalho consiste em discutir como os museus virtuais, em especial o Museu da Pessoa, podem ser utilizados pelos professores, em tempos de Pandemia de Covid-19, em ações didáticas nas disciplinas de História e Geografia do 4º Ano do Ensino Fundamental. Trata-se de um estudo propositivo, resultante de pesquisa bibliográfica e exploratória, com abordagem qualitativo-interpretativa, para o qual foram estabelecidas as transformações e permanências sociais e culturais (História) e a diversidade cultural das regiões brasileiras (Geografia), como recortes de conteúdos, propostos pela BNCC para o 4º ano do Ensino Fundamental, que podem ser trabalhados pelo professor, através das coleções de histórias do Museu da Pessoa, incorporando-se procedimentos investigativos da área de História e Geografia. Constatou-se que as histórias de vida e imagens de pessoas de diferentes regiões do Brasil, que constituem o acervo do Museu da Pessoa, podem ser utilizadas por professores para trabalhar esses conhecimentos de modo contextualizado com a sua realidade junto às crianças. Portanto, o Museu da Pessoa pode contribuir com as ações didáticas do professor, em tempos de Pandemia de Covid-19, em face à construção do conhecimento e o desenvolvimento do pensamento histórico e geográfico pelas crianças do 4º ano do Ensino Fundamental.

Palavras-chave: Museus virtuais. Museu da pessoa. Conhecimento histórico e geográfico. Ações didáticas. Criança.
Evaluation of Resources and Potential Measurement of Wind Energy to Determine the Spatial Priorities for the Construction of Wind-Driven Power Plants in Damghan City
Authors: Zahedi Rahim , Ahmadi Abolfazl , Eskandarpanah Reza , Akbari Mohammadhossein
Published: February 2022

The rate of energy consumption is increasing worldwide due mainly to economic advancement and population growth. As a result, renewable energy sources have gained unprecedented popularity. Wind power has attracted much attention recently as it is economical and does not create environmental pollution. One vital factor that must be considered in the construction of a wind-driven power plant is the selection of a suitable location. Location choice is highly dependent upon the outcome of investigating a potential construction site. This research, along with investigating the effectiveness of parameters for determining a potential location, aims to explore the elements that play a major role in identifying and selecting an optimal wind farm site. The most suitable locations for the construction of wind farms in the city of Damghan were identified and selected through analyzing and integrating maps using GIS software. Within the whole Damghan city area, about 2,240 km2, which comprises 16% of the city’s area has been identified as suitable for establishing wind-driven power plants. By considering the relevant elements and keeping an appropriate distance between the plants to avoid power reduction, it is estimated that a total energy output of about 1,000 MW can be produced by wind-driven power plants in this city.
The First Case of the Subretinal Abscess After Sars-CoV2 Infection
Authors: Kalani Navid , Zare Mohammad Reza , Safniyat Sara , Hatami Naser , Razavizadegan Seyed Ahmad
Published: February 2022

Ever since the new coronavirus has become the cause of the COVID-19 pandemic; it has manifested with unknown and new presentations. In this report, we are presenting a 46-year-old female infected with COVID-19 (confirmed by Reverse transcription polymerase chain reaction (RT-PCR) nasal swab test) and a known case of Diabetes mellitus type 2 who had a history of Intensive care units (ICU)admission due to COVID-19 with uncontrolled diabetes mellitus. In the second admission after recovery, she had blurred vision. Fundus examination revealed multiple yellow-white well-demarcated nonpigmented masses. Diagnosis of the multiple subretinal abscesses was confirmed. KOH-Calcofluor staining of vitreous fluid was negative for fungal infections of the eye. No polymorphonuclear leukocytes (PMN), epithelial cells, nor any organisms were detected. The patient was treated with an injection of the intravitreal Amphotericin B 10 µg/0.1 cc. To our knowledge, the presented case is the first case of the subretinal abscess after COVID-19 infection.
Distribution of anaerobic bacteria and their sensitivity pattern to several antibiotics at the clinical microbiology laboratory of school of medicine, universitas Indonesia, Jakarta in 2019-2020
Authors: Tjampakasari Conny Riana , Prasetyo Dimas Seto , Ningsih Ika , Kiranasari Ariyani
Published: February 2022

Background and Objectives: Anaerobic bacteria are a common cause of endogenous infections, some of which can be life threatening. These bacteria are not easily cultured and isolated and often cannot even found from infected sites. Delayed or inappropriate treatment of these microorganisms can lead to failure in eradicating these infections. The purpose of this study was to determine the diversity of anaerobic bacteria at present and their pattern of sensitivity to several antibiotics.
Materials and Methods: A retrospective study was conducted over a period of two years on various specimens. Specimens derived from body fluids are inoculated on a BacT/Alert (bioMérieux). Anaerobic isolates were identified by Gram staining and continued identification using Vitek 2® automated system. Antibiotic sensitivity examination was carried out using ATBTM ANA (bioMérieux).
Results: A total of 440 specimens were received in microbiology laboratory for anaerobic culture from patients with mul- tiple infections from 13 hospitals in Jakarta. Our research was able to identify 18 species on anaerobic bacteria, consisting 52.5% Gram positive and 47.5% Gram negative bacteria. The most common bacteria found were Clostridium perfringens (15%) from Gram positive and Provetella bivia (10%) from Gram negative. The sensitivity pattern shows that antibiotic piperacilline-tazobactam is 100% effective against anaerobic bacteria, while metronidazole as the drug of choice is only 75% effective. Against Gram positive, several antibiotics such as piperacilline-tazobactam, ticarcilin-clavunic acid, cefoxi- tin, cefotetan, imipenem and  chloramphenicol were 100% effective, however metronidazole occupied the lowest position (61.9%). Meanwhile against Gram negative antibiotics piperacilline-tazobactam is 100% effective and chloramphenicol in the second position (94.75%).
Conclusion: Clostridium perfringens and Provetella bivia are the most common bacteria found. The antibiotics piperacil- line-tazobactam  is 100% effective against both Gram positive and negative. The accuracy of specimen management, isola- tion, identification and sensitivity examination will determine the successful microbiological investigations.
Characterization of Staphylococcus aureus isolates from pastry samples by rep-PCR and phage typing
Authors: Arabestani Mohammad Reza , Kamarehei Farideh , Dini Mahya , Aziz Jalilian Farid , Moradi Abbas , Shokoohizadeh Leili
Published: February 2022

Background and Objectives: Staphylococcus aureus is one of the most common causes of food poisoning. This study aimed to identify S. aureus isolated from pastries, the virulence factors, antimicrobial resistance patterns, biofilm formation, and then classification based on SCCmec types, phage types, and also Rep types.
Materials and Methods: In this study, 370 creamy and dried pastry samples have been randomly collected from different confectioneries in Hamadan city. The S. aureus isolates were identified by conventional microbiological methods and nuc gene amplification. The virulence factors and prophage genes were detected. After that, the biofilm production and antibiotic susceptibility assay of S. aureus isolates were examined. Finally, the isolates were classified by rep-PCR typing.
Results: Among 370 samples, 97 creamy (34.64%) and 3 dried (3.33%) pastry samples were contaminated with S. aureus. Antibiotic sensitivity results showed the highest resistance to penicillin (90%) but none of them were MRSA. According to biofilm formation assay, 14 strains (45%) were strongly adhesive. The dominant phage among isolates was SGF, especially SGFa subgroup. About half of the isolates carried SCCmec Types I and III. Analysis of the genetic linkage between isolates by rep-PCR showed ≥80% genetic similarity and also different rep-types of S. aureus isolates.
Conclusion: The presence of different prophage encoded virulence factors and antibiotic resistance enable S. aureus strains to produce a broad range of diseases. Thus, consumption of creamy pastries increases the risk of infection with S. aureus and it is a serious warning to the health system.
Association of High Levels of Testosterone and Ferritin with Overweight in Women with PCOS
Authors: Barartabar Z , Danesh H , Mazloomi S , Alizadeh N , Pilehvari SH
Published: February 2022

Background & Objective: The present study was conducted to determine testosterone and ferritin levels in women with polycystic ovary syndrome (PCOS) and investigate its relationship with body mass index (BMI)
Materials & Methods: In this case-control study, 104 PCOS cases and 99 controls were included. The concentration of testosterone, ferritin, lipid profile, insulin, glucose, and androgen was measured in fasting blood samples.
Results: Testosterone level was equal to 1.08 ± 0.50 and 0.85 ± 0.42 in the case and control groups, respectively (P< 0.001). Values of ferritin (123.45 ± 18.21ng/dl vs. 92.14 ± 17.74 ng/dl in control group, p< 0.001), insulin (11.41 ± 3.84 µU/ml vs. 7.02 ± 3.29 µU/ml in control group, p< 0.001), and insulin resistance (11.41 ± 3.84 vs.7.02 ± 3.29 in control group, p< 0.001) were also measured. There was a significant relationship between serum concentration of testosterone and ferritin with BMI) p<0.001). The role of ferritin to predict PCOS was significant (ß:-1.1, P< 0.001).
Conclusion: According to the findings of the present study, the levels of testosterone and ferritin were increased in patients with PCOS. Although elevated testosterone levels are effective in PCOS, ferritin concentration is an important factor in predicting and exacerbating the disease.
The Effect of Troxerutin on Apelin-13 and Its Receptor Gene Expression in Ovarian of Pregnant Rats Fed a High-Fat Diet
Authors: Mehri K , Babri Sh
Published: February 2022

Background & Objective: Apelin is a newly discovered member of adipocytokines that acts as an endogenous ligand for the G-coupled receptor for the protein orphan (APJ). This study aimed at investigating the beneficial effect of troxerutin (TRO) on apelin-13 and its receptor mRNA expression in the ovary of high-fat diet (HFD) fed rats.
Materials & Methods: 40 three-week old female Wistar rats received control diet (CD) or HFD for 8 weeks. After mating, pregnant animals were divided into 4 subgroups: CD, CD +TRO, HFD, and HFD + TRO. Respective diets continued to the end of lactation. CD +TRO and HFD +TRO groups received troxerutin (150 mg/kg/day, P.O.) during pregnancy. After weaning offspring, animals in the maternal group were sacrificed. Then blood samples and ovarian tissue samples were collected for further evaluation.
Results: The results indicated that HFD significantly increased serum apelin-13 in HFD dams, which was reversed by TRO treatment. Also, analysis showed that ovarian mRNA expression of the apelin receptor markedly down-regulated in the HFD group compared to control groups. It was also revealed that treatment with troxerutin in the HFD group could significantly increase apelin receptor mRNA expression in comparison with the both CD and HFD groups.
Conclusion: Troxerutin treatment in obese pregnant mothers can affect the function of the reproductive system by modulating the serum apelin 13 and the expression of its receptor gene.
Association of Visfatin with Blood Glucose, Insulin Resistance and Body Mass Index in Patients with Type 2 Diabetes/Pre-Diabetes
Authors: Karimi H , Nezhadali M , Mahdavi M , Saatian M , Saeedi L
Published: February 2022

Background & Objective: In recent studies visfatin plays a role in pathogenesis of many disorders such as obesity and type 2 diabetes. The aim of this study was to evaluate the association of visfatin with fasting blood glucose, insulin resistance and body mass index in patients with type 2 diabetes/ impaired fasting glucose (IFG) compared to non-diabetic subjects.
Material & Methods: This case control study was performed on 160 volunteers. 80 participants were categorized in type 2 diabetic group holding FBG ≥100 (mg/dl) and 80 participants were categorized in non-diabetic group holding FBG 70-100 (mg/dl). Serum visfatin and insulin levels were measured using enzyme-linked immunosorbent assay.
Results: The result was presented as mean± standard deviation and p<0.05 was considered as statistically significant. Diabetic group showed a higher level of age in comparison with the non-diabetics. Meanwhile, the means of TG, FBG, BMI, WC, HC and HOMA were also significantly different between the two groups. Visfatin level was not different between diabetics and normal healthy controls. There was a positive correlation between visfatin and BMI in non-diabetics. Also, in diabetics there was a positive correlation between visfatin and BMI, HDL, Hip, insulin and HOMA-IR and a negative correlation with FBG.
Conclusion: Our study showed an association between visfatin and BMI but not with type 2 diabetes. Also, there was a significant association between this adipokine and insulin resistance in diabetic and pre-diabetic patients which indicates the pathological role of visfatin in insulin resistance.
Antidiabetic and Antihyperlipidemic Effects of Calamus rotang L leaves (Arecaceae) in Streptozotocin-Nicotinamide Induced Diabetic Model
Authors:   Department of Pharmacognosy, JKKN College of Pharmacy, Namakkal, Tamil Nadu, 638 183, India, Kumar V Kishor ​ , Lalitha K G , Kumar R Sambath
Published: February 2022

Background: Calamus rotang L (Asteraceae), also known as Pirampu in India, has long been employed in Ayurvedic medicinal formulations. It has been used to cure diabetes in folklore medicine for centuries. Aim: This Study evaluated the antidiabetic and antihyperlipidemic effects of Calamus rotang L leaves in streptozotocin-nicotinamide (STZ-NC) induced diabetic model. Methods: Estimation of fasting blood glucose, glycosylated haemoglobin, total haemoglobin, lipid profiles, lipoproteins, hepatic marker enzyme activity, and pancreas histopathology was performed in STZ-NC induced diabetic rats after receiving ethanol extract of C. rotang L leaves (100 & 200 mg/kg) for 28 days orally. The data were statistically analysed using one-way analysis (ANOVA) and post hoc multiple comparison tests. Results: The ethanol extract of C. rotang L leaves was given at doses of 100 and 200 mg/kg showed a substantial drop in fasting blood glucose levels and an increase in body weight. HbA1C, TC, TG, LDL, VLDL, AST, ALT, and ALP levels were dramatically lowered by the ethanol extract of the leaves of C. rotang L, whereas Hb, HDL cholesterol levels were significantly increased. Furthermore, in STZ-NC induced diabetes, the C. rotang L leaves ethanol extract has a positive impact on pancreas histological alterations. Conclusions: For the first time, these findings show that the C. rotang L leaves ethanol extract has significant antidiabetic and antihyperlipidemic potential, bolstering the plant's claimed application in the treatment of diabetes and its complications. Keywords Calamus rotang L leaves, Antidiabetic, Antihyperlipidemic, Glibenclamide
Exploratory Study: Measurement Invariance of the Therapeutic Recreation Job Responsibility Scale
Authors: Béland François , Ouellette Pierre , Roussel Hubert , Singleton Jerome , Hopper Tristan
Published: February 2022

The aim of this study was to assess the measurement invariance of the Therapeutic Recreation Job Responsibility Scale (TR-JRS). It measures four dimensions of recreational practitioners’ duties with 27 items: 1) administration, 2) therapy, 3) face-to-face leadership and 4) professional development. Measurement invariance assesses the ability of a single instrument, the TR-JRS, to measure duties among recreational practitioners working in different environments, members of separate professional associations, and to promote different aspects of their work. The sample comprised 417 members of the Canadian Therapeutic Recreation Association and the F´ederation qu´eb´ecoise du loisir en institution. The initial factorial measurement analysis showed metric invariance as the model of choice, though its overall fit was outside the usual acceptable criteria. A factor analysis with a target rotation resulted in a short scale of 14 items with an appropriate Root Mean Square Error of Approximation and Comparative Fit Index. It included the same four dimensions as the 27-item version. A measurement invariance analysis was also run on the short-form scale. The number of factors, position of items within factors, and factor loadings were equal in both groups. The absolute values of the Root Mean Square Error of Approximation and the Comparative Fit Index associated with the short form were over the acceptable cutoff points by a small margin. As expected, items means differed between the two groups and reliability coefficients were high. Such findings reflect this study’s exploratory nature. Hence, further studies on item development could improve fit indices in favor of a stronger invariance status for this scale, which measures an important construct in therapeutic recreation.
Employing an International Research Collaboration Framework to Pilot Test an Evidence-Based Recreational Therapy Program
Authors: Stanojevic Cedomir , Eldridge Lori Ann , McIntire Jordan LiAnn , Bowen Ashley , Dawson Shay , McCormick Bryan , Tamas Daniela , McKissock Blair
Published: February 2022

The field of recreational therapy has well-established methods of scientific collaboration within the United States yet historically there is a scarcity of International Research Collaborations (IRC). IRC could provide many benefits to the field as well as encourage the pollination of new ideas and philosophies to other continents and cultures. The purpose of this paper is to present an IRC framework and to describe the steps that would bring successful IRC to the field of recreational therapy.
Czy teoria ugruntowana wymaga ponownego odkrycia? Esej recenzyjny
Authors: Gorzko Marek
Published: February 2022

Tekst zawiera omówienie książki Barry’ego Gibsona i Jana Hartmana Rediscovering Grounded Theory (2014) na tle dyskusji w obrębie metodologii teorii ugruntowanej. Szczególna uwaga poświęcona jest próbie rekonstrukcji „oryginalnej wersji” teorii ugruntowanej dokonanej przez autorów i związków tej metodologii z wyobraźnią socjologiczną oraz dyskusji, jakiej Gibson i Hartman poddają główne założenia konstruktywistycznej teorii ugruntowanej.
Molecular genetic testing in colon cancer: clinical aspects
Authors: Martianov Aleksandr S. , Kuligina Ekaterina Sh. , Romanko Alexandr A. , Imyanitov Evgeny N.
Published: February 2022

Molecular genetic diagnostics is an essential element to plan for management of colorectal cancer (CRC) patients. The choice of systemic treatment for CRC is impossible without molecular testing of the tumor. For instance, the assessment of the KRAS and NRAS genes is mandatory for consideration of anti-EGFR agents. Tumors with BRAF V600E mutation are characterized by aggressive behavior, the necessity of intensive cytostatic regimens, as well as by sensitivity to combination therapy with BRAF and EGFR inhibitors. Inactivation of the DNA mismatch repair, the MUTYH gene or DNA polymerase epsilon (POLE) leads to an excessive tumor mutational burden; these CRC types are highly immunogenic and therefore respond to immune checkpoint inhibitors. Some colorectal carcinomas are characterized by overexpression of the HER2 oncogene, which make them sensitive to corresponding target therapies. There are CRCs with clinical signs of hereditary predisposition, which require germline genetic testing. Nowadays the molecular diagnosis of CRC is being seriously modified due to worldwide implementation of the next-generation sequencing (NGS) and hypersensitive variants of polymerase chain reaction, for example, droplet digital polymerase chain reaction (ddPCR). Non-invasive liquid biopsy is an example of another highly useful innovation that has growing importance for CRC screening, control of surgical intervention efficacy and monitoring of the disease course.
Clinical features of the microRNA genes methylation in borderline ovarian tumors and depending on the histological structure in ovarian malignancies
Authors: Lukina Svetlana S. , Burdennyy Alexey M. , Filippova Elena A. , Pronina Irina V. , Kazubskaya Tatiana P. , Kushlinsky Dmitry N. , Utkin Dmitriy O. , Braga Eleonora A. , Loginov Vitaly I. , Kushlinskii Nikolay E.
Published: February 2022

Background: Borderline ovarian tumors (BOT) belong to the intermediate type between benign and malignant ovarian neoplasms. Serous borderline tumors share common molecular and genetic characteristics with serous carcinomas. An increase in the methylation level of microRNA (miRNA) genes group has been previously shown during the development and progression of ovarian cancer. However, the study results are contradictory, and their number is not sufficient for a consensus. Current study is the first to search for aberrant methylated genes of the BOT-specific microRNA and for some histological subtypes of ovarian cancer.
Materials and methods: The study was based on a set of 99 paired (tumor/healthy) ovarian tumor samples. Methylation analysis was carried out with quantitative methyl-specific polymerase chain reaction (PCR). Screening for BOT biomarkers was performed in 21 genes of miRNA.
Results: We have found that some miRNA genes (MIR124-1, MIR125B-1, MIR129-2, MIR132, MIR148A, MIR193A, MIR203A, MIR107, MIR1258, MIR339) were characterized by a high methylation level in the patients with BOT, compared to that in the tissues of healthy women. At the same time, the methylation level in the patients with malignant ovarian tumors (MOT) either differed slightly or was even lower. For the MIR129-2, MIR132, MIR148A, MIR203, MIR107 and MIR1258 genes, a higher level of methylation was detected in the BOT patients, compared to the MOT patients. The methylation level of the MIR148A gene in the BOT patients was 4-fold higher than that in the MOT (31.3% vs 7.9%, p = 0.047, multiple two-sided Kruskal-Wallis test). The methylation levels of the miRNA genes MIR148A and MIR191 were significantly reduced in serous cystadenocarcinoma and increased in serous and endometrioid adenocarcinomas.
Conclusion: Methylation of the miRNA MIR148A and MIR191 genes is significantly associated with various histological variants of ovarian cancer. We have shown an increased methylation level of a number of miRNA genes in BOT, compared to MOT. In general, epigenetic factors play a role in the clinical differences between histological forms of ovarian cancer and borderline tumors.
Rheumatoid Arthritis as an Emerging Disability: Vocational Rehabilitation Strategies in the Wake of the Coronavirus Pandemic
Authors: Rumrill Phillip D. , Koch Lynn C. , Park Mirang , Lee Deborah , Bishop Malachy L.
Published: February 2022

Purpose

Americans with rheumatoid arthritis (RA) represent an emerging vocational rehabilitation (VR) clientele.

Method

Following an overview of the etiology, incidence, prevalence, and impact of RA, the authors present strategies to meet the service and support needs of Americans with RA across the phases of the VR process.

Results

The importance of individualized case planning, employer consultation, workplace accommodations, interface with medical and mental health professionals, and adherence to social distancing requirements resulting from the Coronavirus pandemic is emphasized throughout the article.

Conclusions

RA is an emerging disability that can affect people at any age, and rehabilitation counselors must be prepared to meet the service needs of this growing clientele.