bluuebunny/crossref_metadata_2025 huggingface dataset:
Pneumatologia em Lutero
Authors: Wachholz Wilhelm , Dietz Martin Timóteo
Published: December 2018

O texto analisa a pneumatologia na teologia de Lutero. O objetivo do estudo é perceber a correlação da teologia do Espírito Santo em Lutero com sua teologia cristocêntrica. Em consequência do embate de Lutero com os assim chamados entusiastas, que afirmavam revelações diretas pelo Espírito Santo às pessoas, a recepção da teologia de Lutero tendeu a concentrar-se mais na cristologia em detrimento da pneumatologia. Neste estudo, busca-se destacar a centralidade da pneumatologia na teologia de Lutero, ressaltando a atuação Espírito Santo que, utilizando-se de meios criacionais, opera como “ponte” para a presentificação de Cristo pro nobis e como energia transformadora pelo amor a partir da fé do ser humano justificado.
The Antioxidant Effect of Beta-Alanine or Carnosine Supplementation on Exercise-Induced Oxidative Stress: A Systematic Review and Meta-Analysis
Authors: de França Elias , Lira Fábio Santos , Ruaro Marcio Flávio , Hirota Vinicius Barroso , Faria Waziry Paula A. , Fukushima André Rinaldi , Miranda Maria Luiza de Jesus , Caperuto Erico Chagas
Published: December 2018

The objective of this study was to perform a systematic review and meta-analysis of the articles that addressed the effect BA or carnosine supplementation on Physical exercise (PE)-induced oxidative stress (OS). Before May 2018 we searched throughout PubMed, CAPES Periodic and SPORTDiscus human model peer review, randomized control studies with chronic BA or carnosine supplementation on PE-induced OS. A total of 128 citations were found. Only four articles met criteria for inclusion. All four studies used healthy young sedentary, recreationally active or athletic participants. After a chronic BA (~30 days) or carnosine (14 days) supplementation, the studies evaluated PE-induced OS both immediately and several hours after exercise (0.5 to 48 h). In response to PE-induced OS, when compared to placebo, BA/carnosine supplementation increased total antioxidant capacity [TAC; Effect Size (ES) = 0.35, 95% Confidence Interval (CI) 0.06 to 0.65, p = 0.02] and glutathione (GSH; ES = 0.75, 95% CI 0.32 to 1.19, p = 0.0007) concentrations while decreased direct OS markers (ES = −1.19, 95% CI −1.48 to −0.80, p < 0.01) and superoxide dismutase (SOD) activity (ES = −0.58, 95% CI −1.10 to −0.06, p = 0.03). BA or carnosine supplementation did not prevent the increase in indirect OS markers (ES: −0.20, 95% CI −0.59 to 0.20, p = 0.33). In humans, following PE-induced OS, initial treatment trials of BA or carnosine supplementation seemed to increase TAC and GSH concentrations, while decreasing SOD activity. Also, albeit mitigating the acute increase in direct OS species (reactive nitrogen and oxygen species), treatment did not decrease measured values of indirect OS markers (peroxidation or molecule oxidation).
On Sets ${\mathcal X} \subseteq$ $\mathbb N$ for Which We Know an Algorithm That Computes a Threshold Number $t({\mathcal X}) \in$ $\mathbb N$ Such That ${\mathcal X}$ Is Infinite If and Only If ${\mathcal X}$ Contains an eLement Greater Than $t({\mathcal X})$
Authors: Tyszka Apoloniusz
Published: December 2018

We define computable functions $g,h:$ $\mathbb N$ $\setminus \{0\} \to$ $\mathbb N$ $\setminus \{0\}$. For an integer $n \geqslant 3$, let $\Psi_n$ denote the following statement: if a system ${\mathcal S} \subseteq \Bigl\{x_i!=x_k: (i,k \in \{1,\ldots,n\}) \wedge (i \neq k)\Bigr\} \cup \Bigl\{x_i \cdot x_j=x_k: i,j,k \in \{1,\ldots,n\}\Bigr\}$ has only finitely many solutions in positive integers $x_1,\ldots,x_n$, then each such solution $(x_1,\ldots,x_n)$ satisfies $x_1,\ldots,x_n \leqslant g(n)$. For a positive integer $n$, let $\Gamma_n$ denote the following statement: if a system $S \subseteq \Bigl\{x_i \cdot x_j=x_k:~i,j,k \in \{1,\ldots,n\}\Bigr\} \cup \Bigl\{2^{\textstyle 2^{\textstyle x_i}}=x_k:~i,k \in \{1,\ldots,n\}\Bigr\}$ has only finitely many solutions in positive integers $x_1,\ldots,x_n$, then each such solution $(x_1,\ldots,x_n)$ satisfies $x_1,\ldots,x_n \leqslant h(n)$. We prove: (1) if the equation $x!+1=y^2$ has only finitely many solutions in positive integers, then the statement $\Psi_6$ guarantees that each such solution $(x,y)$ belongs to the set $\{(4,5),(5,11),(7,71)\}$, (2) the statement $\Psi_9$ proves the following implication: if there exists a positive integer $x$ such that $x^2+1$ is prime and $x^2+1>g(7)$, then there are infinitely many primes of the form $n^2+1$,  (3) the statement $\Psi_9$ proves the following implication: if there exists an integer $x \geqslant g(6)$ such that $x!+1$ is prime, then there are infinitely many primes of the form $n!+1$, (4) the statement $\Psi_{16}$ proves the following implication: if there exists a twin prime greater than $g(14)$, then there are infinitely many twin primes, {\bf (5)}~the statement $\Gamma_{13}$ proves the following implication: if $n \in$ $\mathbb N$ $\setminus \{0\}$ and $2^{\textstyle 2^{\textstyle n}}+1$ is composite and greater than $h(12)$, then $2^{\textstyle 2^{\textstyle n}}+1$ is composite for infinitely many positive integers $n$.
A Microfluidic Spheroid Culture Device with a Concentration Gradient Generator for High-Throughput Screening of Drug Efficacy
Authors: Lim Wanyoung , Park Sungsu
Published: December 2018

Three-dimensional (3D) cell culture is considered more clinically relevant in mimicking the structural and physiological conditions of tumors in vivo compared to two-dimensional cell cultures. In recent years, high-throughput screening (HTS) in 3D cell arrays has been extensively used for drug discovery because of its usability and applicability. Herein, we developed a microfluidic spheroid culture device (μFSCD) with a concentration gradient generator (CGG) that enabled cells to form spheroids and grow in the presence of cancer drug gradients. The device is composed of concave microwells with several serpentine micro-channels which generate a concentration gradient. Once the colon cancer cells (HCT116) formed a single spheroid (approximately 120 μm in diameter) in each microwell, spheroids were perfused in the presence of the cancer drug gradient irinotecan for 3 days. The number of spheroids, roundness, and cell viability, were inversely proportional to the drug concentration. These results suggest that the μFSCD with a CGG has the potential to become an HTS platform for screening the efficacy of cancer drugs.
International Health Regulations, Ebola, and Emerging Infectious Diseases in Latin America and the Caribbean
Authors: Espinal Marcos , Aldighieri Sylvain , John Ronald St. , Becerra-Posada Francisco , Etienne Carissa
Published: December 2018

The World Health Organization’s determination of the Ebola virus disease outbreak as a public health event of international concern prompted nonaffected countries to implement measures to prevent, detect, and manage the introduction of the virus in their territories. The outbreak provided an opportunity to assess the operational implementation of the International Health Regulations’ core capacities and health systems’ preparedness to handle a potential or confirmed case of Ebola virus disease. A public health framework implemented in Latin America and Caribbean countries encompassing preparatory self-assessments, in-country visits, and follow-up suggests that the region should increase efforts to consolidate and sustain progress on core capacities and health system preparedness to face public health events with national or international repercussions.
Assessment of financial and economic security of the region (based on the relevant statistics of the Donetsk region)
Authors: Derevyanko Bogdan , Nikolenko Liudmyla , Syrmamiik Irina , Mykytenko Yevgen , Gasparevich Iosif
Published: December 2018

In the article, the indicators of financial and economic security of Donetsk region are analyzed. The task of setting statistical estimation of financial and economic security of the region in modern conditions is based on the official materials of the State Statistics Service. For the possibility of further econometric modeling and forecasting, only quantitative indicators are used. This approach limits the number of evaluated indicators, but is considered the most objective. The analysis of financial and economic security is carried out in the context of two spheres of regional development: economic and social. The conducted analysis of the dynamics of the main socio-economic indicators of development of the Donetsk region for the period 2012–2016 allowed to identify the main trends characterizing the development of the region’s economy; provide an assessment of the financial and economic security of the region and identify some “problematic” places of financial and economic security in Donetsk region. Some of the most acute problems were identified in the assessment of financial and economic security and the features of state-legal provision of financial and economic security in the present conditions, as well as the proposed algorithm for monitoring the financial and economic security of the region. The analysis allowed to identify some “bottlenecks” of financial and economic security in the Donetsk region and to demonstrate that close attention and monitoring are required by the level of capital investments, the level of unemployment and the share of households with incomes per month below the legal living wage. The study enables to minimize the risks to form effective directions in assessing the financial and economic security of the region and proposes to optimize on a legal basis the whole mechanism for ensuring the financial and economic security of the region. As a result, the research revealed the most acute problems in assessing the financial and economic security of the region and proposed an appropriate algorithm for monitoring its level.
Can a precast pit latrine concrete floor withstand emptying operations? An investigation from Malawi
Authors: Mchenga Joshua , Holm Rochelle H.
Published: December 2018

For fecal sludge from households in low- and middle-income countries to be treated offsite it needs to be removed, which can be greatly affected by the pit latrine floor design. However, it is unclear whether precast pit latrine concrete floors (latrine slabs) can withstand emptiers and their equipment. To investigate this issue, 28 prefabricated latrine slabs were purchased in two cities of Malawi. They were first visually evaluated, and then their compression strength was tested. Additionally, each seller was asked a series of questions to better understand their business, training, and construction practices. Results showed that households should perform due diligence to ensure that they are purchasing a safe precast latrine slab. Commonly reported problems included nonstandard reinforcement material and spacing, in addition to slabs that were not thick enough or were not large enough in diameter. The results of this research illustrate the inherent complexity in ensuring high-quality decentralized sanitation solutions and how one component, the user interface, if implemented poorly, can affect the rest of the value chain. The findings from this work can help inform training and initiatives that engage artisans and suppliers who play a role in the provision of onsite sanitation service delivery.
Capitate and Lunate Morphology in Normal Wrist Radiographs-A Pilot Study
Authors: Wollstein Ronit , Rubinstein Roee , Friedlander Scott , Werner Frederick
Published: December 2018

Background:

Morphology may provide the basis for the understanding of wrist mechanics.

Methods:

We used classification systems based on cadaver dissection of lunate and capitate types
to evaluate a normal database of 70 wrist radiographs in 35 subjects looking for associations between
bone shapes. Kappa statistics and a log-linear mixed -effects model with a random intercept
were used.

Results:

There were 39 type-1, 31 type- 2 lunates, 50 spherical, 10 flat and 10 V-shaped capitates.
There was a significant difference in lunate and capitate shape between the hands of the same individual
p <0.001. This may be due to different loads on the dominant vs. nondominant hands in the
same individual.

Conclusion:

Further study to better understand the development of radiographic parameters of the
midcarpal joint may aid in our understanding of the morphology and mechanics of the wrist.
T1 Relaxation Time of Achilles Tendon at 3 Tesla with Special Reference to Relevant Clinical Score: A Preliminary Study
Authors: Tbini Zeineb , Mars Mokhtar , Bouaziz Mouna
Published: December 2018

Purpose:

The purpose of this study was to investigate T1 relaxation time of the human
Achilles tendon, to test its short-term repeatability as well as the minimal detectable change, and to
assess the extent that correlate with clinical symptoms.

Methods:

Twenty asymptomatic volunteers and eighteen patients with clinically and sonographically
confirmed tendinopathy were scanned for ankle using a 3 Tesla (T) MR scanner. T1 maps
were calculated from a variable flip angle gradient echo Ultra-short echo time sequence (VFA-GE
UTE) and inversion recovery spin echo sequence (IR-SE) using a self-developed matlab algorithm
in three regions of interest of Achilles Tendon (AT). Signal to Noise Ratio (SNR) between the two
sequences was evaluated. INTRA-class Correlation Coefficient (ICC), Coefficient of Variation
(CV) and the Least Significant Change (LSC) were calculated, to test short-term repeatability of
T1. Subjects were assessed by the VISA-A clinical score. P values less than 0.005 were considered
statistically significant.

Results:

Mean T1 values were 427.09 ± 53.37 ms and 528.70 ± 103.50 ms using IR-SE sequence
and 575.43 ± 110.60 ms and 875.81 ± 425.77 ms with VFA-GE UTE sequence in the whole AT for
volunteers and patients, respectively.

:

T1 values showed a significant difference between volunteers and patients (P=0.001). Regional
variation of T1 in healthy and tendinopathic AT were greater for VFA-GE UTE sequence than for
IR-SE sequence. VFA-GE UTE sequence showed clearly higher SNR compared to IR-SE sequence.
Short-term repeatability of T1 values for volunteers showed an LSC of 22% and 14% for
IR-SE sequence and VFA-GE UTE sequence, respectively. For patients, LSC was 14% and 5% for
IR-SE sequence and VFA-GE UTE sequence, respectively. There was no correlation between T1
and VISA-A clinical score (p>0.005).

Conclusion:

VFA-GE UTE sequence used for T1 mapping calculation demonstrated short acquisition
time and clearly high SNR. Results revealed that T1 relaxation time can be used as a biomarker
to differentiate between healthy and pathologic Achilles tendon. However, T1 showed no
correlation with the VISA-A clinical score.
Diagnostic Value of HLA Typing in Pathogenesis of Cardiomyopathy
Authors: Haybar Habib , Shahrabi Saeid , Shahjahani Mohammad , Rezaeeyan Hadi
Published: December 2018

Development of cardiomyopathy (CM) is dependent upon several factors. However, the reaction of the immune response against myocardial tissue due to microbial and viral infections plays an important role in this disease. Therefore, the purpose of this study is to investigate the relationship between HLAs and their pathogenic mechanisms in the incidence of CM. Relevant literature was identified by a PubMed search (1989-2017) of English-language papers using the terms “Cardiomyopathy”, “Human leukocyte antigen or HLA”, “immune response”, and “polymorphism”. If CM patients are afflicted with viral and microbial infections, HLA class II molecules, which are not expressed on myocardial tissue in normal conditions, are mainly expressed on it. As a result, these HLAs present self- antigens and provoke autoimmune responses against myocardial tissue. On the other hand, the occurrence of polymorphism as well as disrupted expression of miRNAs can affect HLA expression, leading to hypertrophy and fibrosis of cardiac muscle. Finally, it is inferred that the expression evaluation of HLAs as well as identification of polymorphisms in their coding genes can be effective diagnostic factors in the detection of people susceptible to CM.
Unintended Repeat Pregnancies Among HIV Positive Women in Rio De Janeiro, Brazil
Authors: Wittlin Bernardo B. , Carvalho Alice W. , Lima Giulia P. , Andersson Rune , Johansson Susanne , Machado Elizabeth S. , P. Da Costa Tomaz , Hofer Cristina B.
Published: December 2018

Introduction:

High rates of unintended pregnancies among HIV positive women have been reported by several studies. Among repeated pregnancies, these rates may be higher. Our aim was to describe the unintended pregnancy rate in repeat gestations of the same group of HIV-positive women.

Methodology:

From a prospective cohort of HIV-infected pregnant women followed-up from 1995 to 2013 in an Antenatal Clinic (ANC) in Rio de Janeiro, we selected women who had at least two consecutive pregnancies. Patient data were prospectively obtained from standardized questionnaires. The main dependent variable was if the pregnancy was intended or unintended. Some of the other variables were: age, the interval between pregnancies, household income, CD4 cells count at admission in the ANC and at delivery, viral load<1000 copies/ml at admission and close to delivery, and attempts to illegal abortion.

Results:

From a total of 287 women included, the number of unintended pregnancies increased from 138 (63.6%) at first pregnancy to 198 (81.8%) at second pregnancy (p < 0.01). At first pregnancy, we observed 8 women who had made an attempt to illegal abortion (7 with an unintended pregnancy and 1 with a wanted pregnancy, p = 0.06), while at second pregnancy, 34 of them had made an attempt (33 with unintended pregnancy and 1 with a wanted pregnancy, p < 0.01). Regarding viral load suppression close to delivery, there was no statistic difference between first and second pregnancies (72,7% vs. 70,5%, p = 0.36) as well as between intended and unintended pregnancies (in first pregnancy: 80% vs. 86%, p = 0.4; in second pregnancy: 72% vs. 83%, p = 0,1).

Conclusion:

High rates of unintended pregnancies and illegal abortion attempts, along with their increase from one pregnancy to the subsequent, reinforce the need for continuous family planning practices in HIV-infected patients. The majority of the women were able to reach undetectable viral load at the end of the pregnancy, including those with unintended pregnancies.

Implications:

HIV infected patients presenting in antenatal care for sequential unintended pregnancies. Despite the fact that abortion is illegal in this country, a substantial number of women, still attempt it before attending antenatal care. Family planning actions should be performed during the antenatal care.
miR-342-5p as a Potential Regulator of HER2 Breast Cancer Cell Growth
Authors: Lindholm Evita Maria , Leivonen Suvi-Katri , Undlien Eldri , Nebdal Daniel , Git Anna , Caldas Carlos , Børresen-Dale Anne-Lise , Kleivi Kristine
Published: December 2018

Background:

HER2 positive Breast Cancers (BC) have aggressive behavior and poor
prognosis. Previously, we have identified miR-342-5p as an upstream regulator of HER2 signaling,
as well as inhibitor of HER2 positive BC cell line growth.

Objective:

Here, we aimed to further investigate the molecular mechanisms behind miR-342-5pinduced
HER2 pathway deregulation.

Method: Two HER2 amplified breast cancer cell lines were transiently transfected with miR-342-5p
mimic or negative control, and gene expression was analyzed by Agilent microarrays. Three clinical
datasets with BC patients were used to identify correlations between candidate genes and miR-342-
5p, and associations with survival.

Results:

Pathway analyses of all deregulated genes revealed a significant suppression of the HER2
downstream pathways ERK/MAPK and SAPK/JNK, whereas the miR-342-5p predicted target genes
were enriched for pathways associated with cell motility.Biological functions linked to mitochondrial
stability were ranked among the top toxicological functions in both gene lists. Among the most deregulated
genes, Cytochrome B5 Reductase 3 (CYB5R3) and Rap Guanine Nucleotide Exchange Factor
6 (RAPGEF6) significantly anticorrelated and correlated, respectively, with miR-342-5p in all
three clinical BC datasets. Low CYB5R3 levels and high RAPGEF6 levels were significantly associated
with survival, although this was not directly associated with HER2 expression.

Conclusion:

Our data suggest that miR-342-5p overexpression in HER2 positive BC cell lines elicits
broad effects on HER2 downstream signaling, cell motility and mitochondrial stability. Together these
effects may render cells less proliferative and more sensitive to cellular stress.
Bug Report Summarization by Using Swarm Intelligence Approaches
Authors: Kukkar Ashima , Mohana Rajni
Published: December 2018

Background:

Bug reports are considered as a reference document, during the maintenance
phase of the software development process. The developer's counsel them at whatever point
they have to know about the reported bug and need to explore past bug solution. This process requires
a sustainable amount of time due to a large number of comments. Therefore, the best solution
to prevent the developers from reading the whole bug report is to summarize the entire discussion in
a couple of sentences. Bug report summarization is the extraction of some important part of bug reports
that are useful for investigation, resolving the bug with similar problems, reproducing the bug
and checking the status of the bug. If the bug reports have huge volume, variety and velocity information
as big data, extractive bug report summarization would be emerging as an issue. However,
the examiners, find out the bug report summaries do not meet the expectation of the developer; there
is a still need for reading the entire discussion.

Objective:

(1) To generate generalized unsupervised extractive bug report summarization system,
which is easily applicable on any dataset without the need of effort and cost of manually creating
summaries for training dataset (2) To handle the extensive number of comments and generate short
summaries. (3) To reduce the data sparsity, reduction of information, redundancy and convergence
issue for short and lengthy data set. (4) To achieve the semantic summarization solution and explore
the large search space. (5) To provide the facility of adjusting the summary percentage.

Methods:

Particle swarm optimization and Hybridization of Ant Colony Optimization and Particle
Swarm Optimization approaches are used with the advantage of feature weighting technique.

Conclusion:

The efficiency of the proposed approaches are compared with the best existing supervised
and unsupervised approaches. The result shows that the Hybrid swarm intelligence approach
provided better.
A Promising Food-Coaching Intervention Program to Achieve Optimal Gestational Weight Gain in Overweight and Obese Pregnant Women: Pilot Randomized Controlled Trial of a Smartphone App (Preprint)
Authors: Li Ling-Jun , Aris Izzuddin M , Han Wee Meng , Tan Kok Hian
Published: December 2018

BACKGROUND

Traditional dietary recommendations for achieving optimal gestational weight gain are ineffective for pregnant women due to the lack of real-time communication and tedious consultation processes.

OBJECTIVE

In this pilot study, we aimed to determine the feasibility of a novel food-coaching smartphone app for controlling gestational weight gain and macronutrient intake among overweight and obese pregnant women.

METHODS

We designed a randomized controlled trial and recruited 30 overweight and obese pregnant women (1:1 ratio) during 18-20 weeks of gestation and followed them up after 4 and 8 weeks, respectively. Both groups received standard pregnancy dietary orientation at recruitment, while the intervention group received 8 weeks of real-time food coaching via a smartphone app. This food-coaching smartphone app (Glycoleap, Holmusk, Singapore) aimed to improve care and outcomes for people with diabetes. Pregnant women using this app were able to upload food images (eg, a picture of a meal, a drink, or a dessert) and received real-time and detailed food-coaching comments and guidance provided by professional dietitians during the day (8 AM to 8 PM). We recorded detailed characteristics during recruitment and examined anthropometry at all visits. We compared the mean differences of the 8-week gestational weight gain and macronutrient intake between the two groups.

RESULTS

Upon study completion, three subjects dropped out from the intervention, and one gave birth prematurely in the control group. The acceptance rate of the smartphone app was 90%. More participants achieved optimal gestational weight gain per week in the intervention group (8/12, 67%) than in the control group (5/14, 36%). After the 8-week intervention, women in the intervention group appeared to have lower gestational weight gain (mean difference=–0.08 kg; 95% CI –1.80 to 1.63) and cholesterol intake (mean difference=–31.73 mg; 95% CI –102.91 to 39.45) than those in the control group.

CONCLUSIONS

Our findings showed that this food-coaching smartphone app is feasible and favorable for weight gain control and cholesterol intake control among overweight and obese pregnant women. Although our results were not significant (perhaps, attributed to the small sample size), it provided proof of concept for the feasibility of applying such technology in future randomized controlled trials with a larger sample size, an earlier intervention onset, and a longer follow-up for overweight and obese pregnant women.
Неинвазивный мониторинг церебральной оксиметрии у детей
Authors: Snisar V.I. , Pavlysh O.S.
Published: December 2018

В данном обзоре представлен ряд литературных источников, описывающих применение церебральной оксиметрии с использованием инфракрасной спектроскопии у детей. Множество клинических исследований показывают, что, несмотря на некоторые недостатки, неинвазивный мониторинг церебральной оксиметрии является важным инструментом защиты мозга, в первую очередь там, где может присутствовать ятрогенная ишемия головного мозга. Возрастает и количество данных об использовании инфракрасной спектроскопии в таких областях, как педиатрическая кардиохирургия, педиатрическая нейрохирургия, педиатрическая и неонатальная интенсивная терапия. В целом исследования показывают возрастающую роль мониторинга церебральной и соматической оксиметрии. Этот метод представляется полезным как при анестезии, так и в отделениях интенсивной терапии. Однако в настоящее время недостаточно клинических данных о критических уровнях измеряемых переменных, которые необходимы для безопасного ведения периоперационного периода у восприимчивых к церебральной ишемии пациентов, в частности в педиатрии.
Послеоперационная боль у пациенток после лапароскопических операций в гинекологии
Authors: Volkov O.O. , Klygunenko O.M. , Lutsenko V.V. , Braila P.O.
Published: December 2018

Актуальность. Пневмоперитонеум с инсуффляцией углекислого газа является наиболее значимой причиной послеоперационной боли. Уменьшение давления пневмоперитонеума может снизить хирургическую визуализацию. Целью исследования было определение влияния давления пневмоперитонеума на расход анестетиков и опиоидов, восстановление пациенток после лапароскопического вмешательства и раннюю послеоперационную боль. Материалы и методы. В исследование включены 34 женщины (плановая лапароскопическая цистэктомия), которые были рандомизированы в 2 группы: N (n = 18) — пневмоперитонеум с нормальным давлением (12 мм рт.ст.) и H (n = 16) — с высоким давлением (15 мм рт.ст.). Боль оценивали по визуально-аналоговой шкале через 1, 5 и 24 ч после операции. Больные обеих групп были сходны по возрасту, росту, весу, физическому статусу. Данные представлены как М ± SD или % пациенток с параметрами. Тест Манна — Уитни использовался для статистического анализа, p < 0,05 считался статистически значимым. Результаты. Интенсивность послеоперационной боли была достоверно меньше в группе N как через 5, так и через 24 часа, однако не различалась через 1 час после операции. Потребление фентанила, севофлурана и атракуриума не различалось между группами (р = 0,06, р = 0,61 и р = 0,95). Мобилизация статистически не различалась. Количество пациенток, жаловавшихся на боль в плечах через сутки после операции, было недостоверно меньше в группе N. Корреляционный анализ выявил прямую сильную связь между давлением пневмоперитонеума и уровнем ВАШ как через 5 часов (0,73, p = 0,034), так и через сутки (0,65, p = 0,044) после операции. Выводы. При лапароскопической цистэктомии с использованием пневмоперитонеума нормального давления (12 мм рт.ст.) снижается уровень ранней послеоперационной боли по сравнению с пневмоперитонеумом высокого давления (15 мм рт.ст.). Необходимы дальнейшие исследования для установления влияния давления пневмоперитонеума на потребление анестетиков и анальгетиков.
Sejarah Singkat Grha Sabha Pramana UGM dari Khazanah Arsip Universitas Gadjah Mada
Authors: Santosa Heri
Published: December 2018

Penelitian ini bertujuan menyajikan informasi tentang sejarah Auditorium UGM, sehingga memudahkan para peneliti maupun pengguna arsip dalam menemukan arsip berdasarkan tematertentu. Sumber penelitian ini meliputi sumber primer dan sekunder berupa khasanah arsip statis yang ada di Arsip UGM, wawancara serta bahan pustaka. Metode yang dipakai dalam penelitian ini adalah metode penelitian sejarah. GedungAuditorium UGM berdiri tegak dihamparan lahan seluas 11.069,80 meter persegi. Lahan itu, sebelumnya dikenal sebagai lapangan Pancasila. Gedung Auditorium UGM diresmikan dengan sengkalan memet yang berbunyi Catur Kumuda Ambuka Bawana: 1994. Arti sengkalan memet ini adalah bahwa UGM didirikan tahun 1949 dan peresmian Auditorium UGM pada tahun 1994, dengan harapan semoga seluruh sivitas akademika UGM selalu mendapatkan keberuntungan dan kebahagiaan di dalam tugas dan pengabdiannya demi nusa dan bangsa Indonesia. Awalnya fungsi utama Gedung Auditorium UGM digunakan untuk menunjang segala kegiatan akademik yang diselenggarakan oleh Universitas Gadjah Mada tetapi seiring berjalannya waktu gedung ini sekarang bisa dimanfaatkan oleh masyarakat umum dalam bentuk sewa.
Espaços imaginários no filme a Dama na Água de M. Night Shyamalan: a narrativa na pós-modernidade / Shyamalan’s Lady in the water imaginary’s spaces: the narrative at postmodernity
Authors: Silva Valéria Cristina Pereira
Published: December 2018

As obras de arte contemporâneas dizem muito sobre a nossa época, sobre o modo como a percebemos e como a vivenciamos. É com esta intenção que buscamos neste trabalho fazer uma leitura dos espaços imaginários e da narrativa na pós-modernidade a partir do filme A Dama na Água do cineasta M. Night Shyamalan. Dentre os temas que o filme aborda estão a retomada do mito no cotidiano, a emergência do imaginário e o papel que a ficção tem na transformação da realidade. A metodologia da análise fílmica é realizada a partir da semiótica da imagem, da hermenêutica simbólica e do aporte fenomenológico, sobretudo, presente nas obras de G. Bachelard e G. Durand. No filme o lugar sofre mudanças a partir do reencantamento, da presença do mito e o espaço transforma-se à medida em que os personagens envolvem-se para salvar Story, ao passo que adquirem outra perspectiva para encarar o mundo a sua volta. O enredo traça uma ideia de despertar, como ir além, devolvendo à vida e ao lugar, o sonho de uma narrativa a muito esquecida. Com a narrativa sobre um livro dentro do filme e uma história que fala sobre história, a metaficção presente no filme entrecruza ao longo da trama os papéis da narrativa fílmica e literária, reservando um papel contundente à critica. É nesta atmosfera complexa que buscaremos encontrar na filmografia de A Dama na Água traços na nossa pós-modernidade latente.
Geografia, representação e arte em Vincent van Gogh: uma leitura do “Passeio ao crepúsculo” / Geography, representation and art in Vincent van Gogh: a reading d”Landscape with couple walking and crescent moon”
Authors: Rodrigues Jean Carlos
Published: December 2018

Este artigo estabelece uma relação entre Geografia e Arte de modo que possamos refletir sobre o que há de arte na geografia e o que há de geografia na arte. Esta interface é no intuito de contribuir com um debate da Geografia no qual a Arte, pensada enquanto representação, seja vista como expressão do espacial presente no significado que a cultura atribui à existência. NaArte, analisamos o quadro “Passeio ao Crepúsculo”, de Vincent van Gogh, produzido em um contexto posteriormente denominado de Pós-Impressionista por ser a expressão artística de um século (XIX) no qual diversas outras revoluções entraram em curso na Europa e alteraram os sentidos das coisas. NaGeografia, os pilares para tal discussão estão estabelecidos na relação entre a paisagem e a sua representação nas pinturas. A arte, como forma simbólica, constitui representações que expressam as geografias pós-impressionistas, sobretudo de Vincent van Gogh
Lugar: uma perspectiva experiencial / Place: an experiential perspective
Authors: Tuan Yi-Fu
Published: December 2018

Independe de tamanho e de características físicas a atribuição da alcunha “lugar” às diversas percepções do homem sobre os espaços vividos. Da lareira à nação, é vasta a gama de fenômenos que podem ser tidos como lugares. Em seu texto, publicado em 1973, Yi-Fu Tuan amplia e eleva as discussões acerca da multiplicidade de lugares, os quais são legitimados pela experiência, dentre eles o lar e seus interiores, a cidade e sua urbanidade, a vizinhança, a região e a nação-estado. Experienciar tais lugares ativa e passivamente é primordial, uma vez que o lugar é construído a partir da experiência física, mental, sensorial, psicológica no espaço vivido: é centro de significado.
Apresentação: Periferias da Paisagem
Authors: Holzer Werther , Araujo Eloisa Carvalho de
Published: December 2018

Apresentação do Dossiê temático Periferias da Paisagem.
Habitar lá fora: ócio e experiência geográfica de crianças ao ar livre / Inhabit out there: idleness and geographical experience of children out of doors
Authors: Vieira Leandro Pessoa
Published: December 2018

Desde a descoberta da gravidez da esposa, da chegada da filha e, consequentemente, a do nascimento de um pai, no caso, eu, me interessei e dediquei meu tempo para estudar a criança através de uma perspectiva geográfica. Assim, nesse trabalho, descrevi as experiências geográficas de crianças ao ar livre com base no emaranhado fenomenológico de Dardel e Ingold. Observando, participando, interagindo e comunicando as vivências das crianças ocorridas em espaços ao ar livre na cidade de Salvador, construí uma poético-análise, baseada nos pressupostos de Bachelard, situando as experiências geográficas de crianças e sua ressonância em mim. Ao ar livre, uma geografia sensível, íntima e fértil se revelou diante do espanto, maravilhamento e da imaginação do encontro com o espaço.
The Determinant of Takaful Acceptance: Theory of Reasoned Action Approach
Authors: Hasyim Fuad
Published: December 2018

Indonesia has great potential for Islamic insurance (takaful) based on the ratio of GDP. But still very few Indonesians, who have used Islamic insurance as a form of risk management and financial planning. This can be seen from the data, Indonesia has low literacy index and financial inclusion, mainly on conventional insurance (15.8% literacy, 12.1% inclusion) and Islamic insurance (2.51% literacy, 1.92 inclusions). This study aims to reveal why the low of Islamic insurance acceptance in Indonesia. This research uses a quantitative method, using the Theory of Reasoned Action Approach (TRA). The TRA construct identifies the effect of Attitude and Subjective Norms on Behavior through Intention. TRA constructs can be measured using the Structural Equation Modeling method with Partial Least Square (SEM-PLS). The results found that acceptance of Islamic insurance is influenced by attitude and subjective norms. Technically, either directly or indirectly, attitude variables affect the behavior through intention (sig. 0,000) or subjective norms variable affect to behavior through intention (Sig. 0,003
Pengaruh Pendapatan Asli Daerah dan Dana Perimbangan terhadap Indeks Pembangunan Manusia
Authors: Rahmayati Anim , Pertiwi Imanda Firmantyas
Published: December 2018

This study aims to examine the effects of local revenue and balancingfunds consisting of general allocation funds, special allocation funds andrevenue-sharing funds on the human development index of districtgovernments/ city in Central Java. The level of Human DevelopmentIndex in Central Java from year to year has fluctuated changes inthe increase and including the medium category.The research methodused in this is quantitative research using multiple linear regressionanalysis tools. The sample used in this study is the district governmentfinancial statements in Central Java during 2015-2016 whichamounted to 70. The result of the research shows that the originalincome of the region influences the human development index. Whilegeneral allocation funds, special allocation funds and profit-sharingfunds have no effect on the human development index. This indicatesthat the fulfillment of education, health and poverty eradication needsin Central Java can be met from the local revenue in each districtgovernmentKeywords: Local original revenue, general allocation fund, special allocation fund, profit-sharing fund, human development indexJEL Classification: H61, H77
Considerations on the importance of proper heat transfer coefficient modeling in air cooled electronic systems
Authors: Janicki Marcin , Samson Agnieszka , Raszkowski Tomasz , Torzewicz Tomasz , Napieralski Andrzej
Published: December 2018

This paper illustrates, based on a practical example of a hybrid circuit, the
influence of proper heat transfer coefficient modelling in air cooled
electronic systems on the accuracy of thermal simulations. This circuit
contains a transistor heat source and a set of temperature sensors. The
measurements of their temperature responses are taken in natural convection
and forced air cooling conditions. The experimental data provide the
information necessary to estimate the local heat transfer coefficient values
in heat source and temperature sensor locations. Moreover, the experiments
rendered possible the fitting of parameters of an empirical heat transfer
coefficient model for different surface temperature rise values and cooling
air velocities, and hence allowed significant improvement of thermal
simulation accuracy.
Design of planar plate monopole antenna with vertical rectangular cross-sectional plates for ultra-wideband communications
Authors: Naghdehforushha Seyed , Bahaghighat Mahdi , Salehifar Mohammad , Kazemi Hossein
Published: December 2018

In this paper, a novel design for planar plate monopole antennas is proposed
with applications to ultra-wide band (UWB) communications. To verify the
proposed antenna design, simulations are performed by means of CST and HFSS
software tools, showing that the impedance bandwidth is significantly
increased by vertical cross-sections. By adding a series of parameters to the
vertical cross sections, the antenna efficiency is effectively enhanced by
achieving a return loss of 10 dB over the bandwidth range between 3.1 GHz and
10.6 GHz. In addition, our experimental results demonstrate that the
fabricated antenna has a return loss performance similar to that obtained by
the simulation results.
Innovative environmentally friendly technology for copper(II) hydroxide production
Authors: Milosavljevic Milutin , Babicev Ljiljana , Belosevic Svetlana , Danicic Dunja , Milosevic Milena , Rusmirovic Jelena , Marinkovic Aleksandar
Published: December 2018

The innovative laboratory procedure for the synthesis of copper(II) hydroxide
in the form of the aqueous suspension was developed. The reaction mechanism
consists of the reaction between copper(II) sulphate pentahydrate and sodium
carbonate by successive ion exchange of carbonate ions with the hydroxide
ones in a multistep process. Production of copper(II) carbonate and sodium
sulphate by reacting of copper(II) sulphate with sodium carbonate was
followed by addition of sodium hydroxide solution whereby the product,
copper(II) hydroxide, was obtained by releasing an equimolar amount of sodium
carbonate. It was determined that, the equimolar reaction of copper(II)
sulphate and sodium hydroxide lead to the maximal reactants exploitation.
Sodium phosphate, formed in the final process stage by addition of 10 %
phosphoric acid solution, acted as a copper(II) hydroxide stabilizer. High
yield of the product was obtained by optimizing the synthesis parameters:
reaction time, molar ratio of reactants and the reaction temperature. The
obtained product was formulated to obtain a commercial product, which is used
as a fungicide and bactericide.
Quality of life of laryngectomized patients in Serbia
Authors: Krejovic-Trivic Sanja , Milovanovic Jovica , Parapid Biljana , Vukasinovic Milan , Mikovic Nikola , Trivic Aleksandar
Published: December 2018

Introduction/Objective. Total laryngectomy is a very mutilating operation and it leads to drastic changes in life quality. The purpose of this study was to examine factors of importance to the laryngectomized patients? quality of life and to evaluate characteristics of esophageal voice and speech. Methods. The study was conducted at the Clinic of Otorhinolaryngology and Maxillofacial Surgery, at the Clinical Center of Serbia (Belgrade, Serbia), during the period between March 2012?2015. The study included 223 patients diagnosed with laryngeal cancer, who underwent total laryngectomy. The total of 168 laryngectomized patients were provided with phoniatric rehabilitation. Results. The quality of life was significantly better for those laryngectomized patients who did undergo phoniatric rehabilitation. By means of intensive phoniatric rehabilitation the esophageal voice and speech was established in 86.3% of laryngectomized patients registered by objective acoustic analysis. Rehabilitated laryngectomy patients had a significantly lower presence of voice handicap sense (VHI: 19.57 ?} 7.35) and expressed significantly lower symptoms of depression and anxiety (PHQ-9: 3.8 ?} 4.2; GAD-7: 3.4 ?} 4.2). Cronbach?s alpha coefficient was above 0.7 EORTC QLQ-C30 on three levels of Likert scales: the scale of physical and emotional functioning and fatigue; as well as EORTC QLQ-H&N43 questionnaire: the symptoms of head and neck pain, speech, swallowing and eating problems and body image. Conclusion. Significantly improving the quality of life of laryngectomized patients was achieved by a multidisciplinary rehabilitation. Phoniatric rehabilitation carried out in a planned and systematic way is the most efficient rehabilitation of laryngectomized patients.
Comments of the Auditing Standards Committee of the Auditing Section of the American Accounting Association on International Auditing and Assurance Standards Board Exposure Draft, Proposed International Standard on Auditing 315 (Revised): Identifying and Assessing the Risks of Material Misstatement and Proposed Consequential and Conforming Amendments to Other ISAs
Authors: Brown Veena Looknanan , Coram Paul J. , Dennis Sean A. , Dickins Denise , Earley Christine E. , Higgs Julia L. , Schaefer Tammie J. , Tatum Kay W.
Published: December 2018

On July 16, 2018, the International Auditing and Assurance Standards Board (the Board or IAASB) issued a request for comment on its Exposure Draft, Proposed International Standard on Auditing 315 (Revised): Identifying and Assessing the Risks of Material Misstatement and Proposed Consequential and Conforming Amendments to Other ISAs (ED-315). Major enhancements proposed include explicit recognition of the auditor's use of automated tools and techniques, requiring an understanding of an auditee's use of information technology relevant to financial reporting, acknowledging the influence of an entity's complexity on the audit plan, and increasing the emphasis on the need for professional skepticism. The comment period ended on November 2, 2018. This commentary summarizes the participating committee members' views on selected questions posed by the IAASB.

Data Availability: ED-315, including questions for respondents, is available at: https://www.ifac.org/publications-resources/exposure-draft-isa-315-revised-identifying-and-assessing-risks-material.
Tradisjonelle organisasjoner og nye frivillige initiativ i flyktningsituasjonen høsten 2015. Mobilisering eller forsterkning av eksisterende skiller?
Authors: Fladmoe Audun
Published: December 2018

This chapter studies voluntary contributions in Norway during the refugee crisis in 2015. Due to increased asylum arrivals, the public reception centers were overloaded and there was an urgent need for assistance from civil society actors. In addition to contributions from traditional voluntary organizations, a number of new voluntary initiatives were established. This makes the migration crisis a unique case for studying new forms of engagement: Did the migration crisis mobilize new groups of volunteers, or did the situation rather reinforce existing cleavages between volunteers and non-volunteers? Based on survey panel data carried out before (2014) and after (2016) the migration crisis we analyze cleavages between volunteers and non-volunteers related to variations in sociodemographic background and political party preferences. The results show indications of both mobilization and reinforcement of existing cleavages, but in the long run existing cleavages seems to be preserved. Compared to the traditional organizations, new voluntary initiatives recruited more contributions from the young, low educated and low-income groups, but the number of ‘new’ volunteers was limited – the majority of those who contributed had previous experience as organizational volunteers. Furthermore, we find few indications that involvement during the migration crisis contributed to increased participation in traditional voluntary work a year later. Thus, the results suggest that, in the context of the migration crisis, we observed a short-term mobilization of some new groups, but in the longer run, the voluntary sector is characterized by established cleavages between volunteers and non-volunteers.
Nasjonale organisasjoners bruk av sosiale medier. Muligheter og barrierer for bruk
Authors: Beyer Audun , Steen-Johnsen Kari
Published: December 2018

In this chapter, we investigate the ways in which national voluntary organizations have employed new digital media. We study in particular whether digitization seems to enable new organizational forms; if it contributes to new ways in which organizations can engage members and volunteers; and how the new digital media can contribute to, for example, public debate. We ask if organizations differ in such use, and whether certain types of organizations are more likely to use new forms of communication, both to inform members and to participate in the public. For instance, do organizations that were established after the rise of social media (digital natives) use new media differently than older organizations? Secondly, we investigate what kinds of barriers that can prevent the use of social media by such organizations

Our findings initially point out that the use of internet and social media largely permeates all types of organizations in Norway, but that there are important differences between different organizations. Furthermore, we identify different dimensions in terms of the use of social media, with clear distinctions between public activities on the one hand and activity directed at members on the other. Finally, we find that a lack of resources is the main causal factor when it comes to the organizations that not use social media.