bluuebunny/crossref_metadata_2025 huggingface dataset:
Retained Foetus-in-Fetu or Fetiform Teratoma – A Diagnostic Dilemma and Operative Challenge
Authors: Kumar Pankaj , Mishra Tushar S , Sable Mukund Namdev , Sankaran Sindhu , Samal Swagatika
Published: January 2023

Foetus-in-fetu (FIF) is a condition where one of the twin foetuses is found developing inside the other. Differentiating this condition from fetiform teratoma (FT), in which the teratoma becomes highly differentiated to take a foetus-like appearance, often becomes arduous. Unfamiliarity with the situation and the presence of bone and hair within such lesions can potentially mislead the surgeon to diagnose it as a dermoid cyst erroneously. Suboptimal surgery can complicate things further when it comes to redoing operations and the final histopathological reporting. We report this case of a partially removed cystic retroperitoneal mass in a 14-year-old male, posing a significant surgical challenge due to dense adhesions to the vital retroperitoneal structures, such as common iliac vessels and ureter. We also faced similar diagnostic dilemmas during histopathology due to the tissues removed during the previous surgery. Based on gross and microscopic features, the possibility of a FIF or FT was rendered.
Knowledge and Awareness of Aetiological and Risk Factors as Determinants of Health-Seeking Pattern of Parents of Children with Epistaxis in a Tertiary Health Institution: A 7-Year Prospective Study
Authors: Aremu Shuaib Kayode
Published: January 2023

Aim:

This prospective study aimed to assess the knowledge and awareness of aetiological and risk factors as determinants of the health-seeking pattern of parents of children with epistaxis in a tertiary health institution.

Materials and Methods:

This was a 7-year cross-sectional prospective study where copies of the questionnaire were distributed to consenting parents whose children presented to our institution with epistaxis between January 2015 and December 2021. A total of 570 parents were enrolled in the study in the research time period.

Results:

Out of 570 patients, majority (39%) were aged between 11 and 15 years, followed by 35% aged between 6 and 10 years, 17% aged between 1 and 5 years and 11% aged between 16 and 18 years. Three hundred and eighty (66.67%) were male and 190 (33.33%) were female. Two hundred and ninety-five (51.75%) patients had primary education, followed by 189 (33.16%) patients with secondary education and 86 (15.09%) patients with preschool education. Three hundred and seventy-three (65.44%) patients had anterior bleeding and 107 (18.77%) patients had posterior bleeding while 90 (15.79%) patients had both anterior and posterior bleeding. The majority of the parents, 399 (70%), were aware about the epistaxis while 171 (30%) parents were unaware about the epistaxis.

Conclusion:

A significant number of parents are unaware of the epistaxis and also unaware of the various aetiological and risk factors of the epistaxis and these issues need a more nuanced analysis in light of Africa’s rich cultural diversity.
Giant Colpolithiasis in Urogenital Sinus Anomaly with Urethral Duplication
Authors: Dudhani Shreyas , Sinha Amit Kumar , Kumar Bindey , Kumar Amit , Anant Monika
Published: January 2023

Primary vaginal calculi are uncommon in children. Urethral duplication in females is seen to occur in association with complex congenital malformations. We report the case of perianal persistent urogenital sinus with a hypertrophied clitoris with phallic urethra, scrotum-like pouch, uterus didelphys with obstructed hemivagina, and giant colpolithiasis in 46XX female. A 16-year-old presented with pain abdomen and cyclic passage of blood clots per rectum. She had a tender lump in left iliac region, a phallus like protrusion and a ruggous sac below it. Vaginal opening was absent. Computed tomography showed two uterine horns with a separate cervix and distended non-communicating hemivaginas with a large calcified oval mass in the left hemivagina. On exploration, calculus was extracted from the left hemivagina. The large calculus found in the left hemivagina appears to be the cause of all presenting symptoms. It obstructed the left hemivagina, filling the left uterine horn with menstrual blood causing its gradual enlargement and secondary infection. The early diagnosis and prompt referral of such an anomaly can only be ensured in institutional deliveries. For a significant proportion of newborns in the developing world, the ability to afford or even be referred to institutes which deal with such cases is a luxurious affair. We hope to bridge bridging the knowledge, attitude and practice gap that exists in our health-care system with this report.
Effect of predialysis fluid overload on sleep quality in hemodialysis patients
Authors: Hussein Hussein S. , Abdelaziz Haitham E. , Ahmed Mohamed A. , Emara Ahmed A.
Published: January 2023

Background

Sleep disorders are common among end-stage renal disease patients undergoing hemodialysis (HD). The etiology of sleep disorders in these patients is known to be multifactorial. However, the role of hydration status in sleep disorders in HD patients is not well studied. Therefore, our aim was to study the effect of predialysis fluid overload on sleep quality in HD patients.

Patients and methods

This cross-sectional study included 100 prevalent HD patients from the HD unit of El Sahel Teaching Hospital. Fluid status and fluid compartments [total body water), extracellular water (ECW),and overhydration (OH) index] were analyzed by a portable whole-body bioimpedance spectroscopy (body composition monitor) before a mid-week dialysis session. OH was defined as OH/ECW% more than or equal to 15%. HD patients were then classified into two groups: group 1 (normohydrated) and group 2 (overhydrated) according to the relative OH index (OH/ECW%). Sleep quality was assessed in all patients by the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients with concurrent diagnosis of either obstructive sleep apnea or psychiatric disorder and patients on any medications that affect the sleep pattern were excluded.

Results

Our study included 100 HD patients (49 male, 51 female; mean age, 49.3 ± 11); 42 (42%) patients had OH (i.e. group 2). Poor sleep quality (defined as PSQI score ≥5) was reported in 57% (n=57) of HD patients included in our study. Poor sleep quality was significantly higher in the HD patients with OH (group 2). Total PSQI scores were significantly higher in overhydrated patients (group 2) compared with normohydrated patients (group 1) (7.92 ± 3.32 vs. 4.83 ± 2.27, P≤0.001). The component scores 1, 2, 3, 4, 6, and 7 of the PSQI showed significant higher values (i.e. poor sleep quality) in overhydrated patients (group 2). Moreover, there was significant positive correlation between total PSQI score both of OH (r=0.259, P=0.009) and OH index (OH/ECW%) (r=0.283, P=0.004) in all HD patients included in the study.

Conclusion

We may conclude from our study that sleep disorders are prevalent in HD patients. Predialysis fluid overload in HD patients may be associated significantly with poor sleep quality.
Serum immunoglobulin G as a predictive marker of early renal affection in type-2 diabetic patients
Authors: Abdellah Mohammad H.M. , Tawfik Nabawia M. , Tony Effat Abd-Elhady , Mahmoud Amal A.A. , Ali Seham M. , Khairallah Marwa K.
Published: January 2023

Background

Chronic hyperglycemia is a characteristic feature of diabetes mellitus and responsible for its long-term microvascular and macrovascular complications. One of the most problematic issues concerning diabetes complications is diabetic nephropathy ending with renal impairment and costly treatment. Defining new biomarkers to detect renal affection in diabetic patients is necessary. So, we aimed to evaluate serum immunoglobulin G (IgG) as a marker of early renal affection.

Patients and methods

In this study, 50 patients with type-2 diabetes were selected and classified according to their albuminuria and glomerular filtration rate, 25 apparently healthy participants were enrolled as a control group. We measured serum IgG levels in patients and control groups.

Results

Significant higher mean levels of serum IgG were observed with diabetic patients more than the control group and higher in patients with normoalbuminuria and microalbuminuria with P value less than 0.001 for each, however, significant lowest mean levels of serum IgG in the patients with macroalbuminuria when compared with other degrees of albuminuria, significantly higher mean levels of serum IgG were observed in stage-IV nephropathy when compared with other stages of chronic kidney disease (P≤0.001). There was a significant positive correlation between serum IgG and blood urea, serum creatinine, glycosylated hemoglobin, and albuminuria and proteinuria, and a significant negative correlation with estimated glomerular filtration rate with a significant difference in microvascular and macrovascular complications between the stages of chronic kidney disease and serum IgG levels.

Conclusion

Serum IgG is a simple test that can be used as a predictive biomarker for early renal affection in type-2 diabetic patients.
Brain fog and vessel clogs
Authors: Maitray Aditya , Kuriakose Anju , Rajendran Anand , Srinivasan Karthik , Mahalingam Maanasi
Published: January 2023

We present a unique case of a 36-year-old female presenting with features suggestive of bilateral combined vascular occlusion, hearing loss, and encephalopathy. Multimodal imaging was done for both eyes fundus evaluation including wide-field color fundus photography, optical coherence tomography, and fundus fluorescein angiography. After extensive ocular and systemic investigations, she was diagnosed to have Susac syndrome (SS). She was referred to a neurologist and otologist for systemic evaluation and underwent laser photocoagulation in both eyes, followed by pars plana vitrectomy in her left eye. Combined bilateral retinal vascular occlusion in association with SS is very rare.
Kleopatra, Imperialismus und Orientalismus
Authors: Šterbenc Erker Darja
Published: January 2023

Im Aufsatz werden die literarischen Bilder der Kleopatra VII analysiert, der Königin des antiken Ägypten, welche die Verbündete des Antonius in seiner Auseinandersetzung mit Oktavian war. Oktavian hat Antonius und Kleopatra in der Schlacht bei Actium im Jahr 31 v. Chr. besiegt und Alexandrien im drauffolgenden Jahr erobert. Er propagierte Antonius als den verweiblichten Ehemann der Orientalin Kleopatra, der vermeintlich in Ausschweifung und außerordentlichem Luxus gelebt und eine drohende Gefahr für das römische Imperium und den Westen verkörpert habe. Darüber hinaus werden die Transformationen untersucht, die Kleopatras Bild in verschiedenen literarischen Gattungen in der Antike unterlief, seine Rezeption in der Renaissance-Malerei und im modernen Film. Dabei wird der Orientalismusbegriff von Edward Saïd in Bezug auf Aischylos’ Perser nuanciert, um herauszustellen, dass er die Perser nicht nur als mit griechischen Sitten vertraut darstellt, sondern auch als Barbaren. Weiter wird diskutiert, wie Oktavian durch seine politische Invektive gegen Antonius das Bild von Kleopatra beeinflusst hat. Augusteische Dichter arbeiteten in ihre Gedichte einige Reflexe von Oktavians Bild der ägyptischen Königin im Einvernehmen mit den Tropen ihrer jeweiligen literarischen Gattung ein. Horaz stellt in der Epode 9 Kleopatras Ehemann Antonius in einer der Invektive ähnlichen Weise als ihren Sklaven und Eunuchen dar. Im ersten Teil der Ode 1.37 suggeriert Horaz, Kleopatra sei ein Monster und eine verruchte Königin, wohingegen er im zweiten Teil betont, dass sie ihre Niederlage mit der Würde einer guten Herrscherin angenommen habe. Römische Elegiker schildern Kleopatra passend zu den Tropen der Liebeselegie als elegische Herrin und Antonius als ihren Sklaven. Vergil inszeniert in seiner Aeneis den Zusammenprall zwischen Kleopatras Osten und dem Westen, welcher durch Augustus repräsentiert ist, aber der epische Erzählrahmen der Episode, die Ekphrasis von Aeneas’ Schild, betont ihren fiktiven Charakter und hebt die Fluidität der stereotypen Zuschreibung von Fremdheit und Weiblichkeit hervor. In der europäischen Malerei und in Filmen eignete man sich stereotype und orientalisierende Kleopatra-Bilder an. Seit der Neuzeit ist Kleopatra zu einer konstruierten Figur geworden, die häufig im Dienste der orientalistischen Machtdiskurse, des nationalstaatlichen Imperialismus und im letzten Jahrhundert auch der Käuferlenkung steht.
Valores de universalidad y representaciones simbólicas (escritores españoles extraterritoriales)
Authors: Baena Peña Enrique
Published: January 2023

A partir de las vanguardias, la quiebra estética del universo cerrado dio carta de naturaleza de modo agudo a la autoconciencia literaria. Asimismo, frente a una invención unívoca, lo extraterritorial asumió un papel renovador en el propio desarrollo de esta autoconciencia. Afloran en ello raíces de universalidad y de representaciones simbólicas, a partir de las propias lejanías espaciales. Una inmensa capacidad del imaginario donde no solo se desvela la utopía, junto a los procesos de persuasión, sino también el abismo de la escritura y su carácter fragmentario. Proyecciones que alentaron en el círculo de escritores tratados la rehumanización, que daba entrada a otra época, a un camino de futuro fundado en la expresividad existencial, su realización en lo histórico y los sincretismos entre poesía, filosofía, ensayo y narratividad. María Zambrano, Emilio Prados, Manuel Altolaguirre, José Gaos, José Moreno Villa, Juan David García Bacca, Luis Cernuda, Manuel Andújar, José Bergamín o Adolfo Sánchez Vázquez, entre otros, componen el conjunto de los autores que desde el exilio en México protagonizaron uno de los capítulos más relevantes de la autoconciencia literaria y estética contemporánea en el orbe hispánico.
Potere imperiale romano e strumenti eulogistici greci
Authors: Pitotto Elisabetta
Published: January 2023

Il presente articolo assume due celebri passi di Virgilio (Eneide, VI 860–886) e di Orazio (Odi, IV 2) come casi di studio per indagare la relazione fra il potere imperiale romano allo stato nascente e gli strumenti eulogistici di tradizione greca. In mancanza di modelli ellenistici specificamente riconoscibili, l’“epicedio per Marcello” sembra riproporre motivi topici della lirica celebrativa arcaica: la bellezza come simbolo esteriore di valentia; la lode come elogio non strettamente ad personam, ma da rivolgere all’intera casata del destinatario; la poesia come insostituibile strumento di gloria immortale. Lo stesso vale per l’ode ad Augusto vincitore sui Sigambri, tutta giocata sul rapporto con il modello pindarico, e condotta secondo un accorto uso della recusatio e della praeteritio che ricorda la struttura dell’“encomio a Policrate” ibiceo. Nel momento stesso in cui viene a formarsi l’impero romano, e di conseguenza si manifesta la necessità di offrirne una rappresentazione letteraria che possa diventare paradigmatica, due fra i massimi poeti augustei si volgerebbero dunque agli autori della lirica greca arcaica, noti e praticati nella Roma del tempo, di cui riprendono temi e arsenale retorico: pare emergere, insomma, una tendenza di riappropriazione retorico-letteraria, meritevole di indagini sistematiche su un campione testuale più ampio.
Costruire e ri-costruire la storia e l’identità d’Asia in età imperiale
Authors: Di Benedetto Paolo
Published: January 2023

Nell’antica Grecia, il mito delle Amazzoni, che, nell’immaginario collettivo greco, rappresentavano l’elemento “altro”, è spesso associato a tradizioni di fondazione e di eponimia in rapporto a città, soprattutto nella Ionia e nell’Eolide d’Asia Minore. Queste tradizioni si possono rintracciare in racconti locali, che si sono conservati fino all’età imperiale romana, in un momento in cui, in particolare, si assiste ad una ripresa delle tradizioni greche arcaiche e classiche durante la seconda sofistica. L’epoca dell’imperatore Adriano, più di ogni altra, sarebbe stata importante per la rinascita ed il recupero di questi miti di fondazione, in quanto molte città ioniche ed eoliche (come Efeso, Smirne, Cuma e Mirina) creavano un nesso con il loro passato e con la loro origine per mezzo della figura dell’Amazzone, rappresentata anche sulla monetazione locale, con l’obiettivo di affermare la loro antichità e priorità: tali tradizioni sono attestate anche nelle fonti letterarie. Grazie alla remota antichità ed adattabilità, il mito di fondazione basato sulle Amazzoni attraversò diversi processi di rielaborazione e rifunzionalizzazione e fu riutilizzato come “paradigma” in Asia Minore, soprattutto in età imperiale, per sottolineare l’archaiologia delle antiche poleis. Queste elaborazioni, fondate su antiche tradizioni mitiche locali, sono state determinanti per riaffermare e rivendicare l’identità culturale ed etnica dei Greci sotto l’Impero romano in un preciso momento storico. Obiettivo del presente lavoro è indagare i processi di costruzione e ri-costruzione dell’identità cittadina attraverso l’analisi delle fonti relative ai racconti di fondazione e di eponimia attestati in Ionia e in Eolide in relazione al particolare contesto legato al revival delle tradizioni locali greche in età imperiale.
Krščanski imperij in cerkvena zgodovina
Authors: Petrič Matej
Published: January 2023

Članek je posvečen Cerkveni zgodovini, ki jo je po gotski invaziji v severno Italijo v letu 401/402 napisal Rufin iz Akvileje, eden najvidnejših latinskih krščanskih piscev poznega 4. in zgodnjega 5. stoletja. Rufinova Cerkvena zgodovina je v osnovi prevod istoimenskega dela Evzebija iz Cezareje, ki sta mu dodani dve knjigi, v katerih Rufin opisuje dogodke iz let 325–395. Članek predstavi, na kakšen način je Rufin v tem dodatku sledil praksi in temam, ki jih je v svojem delu ustoličil Evzebij, pri čemer Rufinovo metodo ponazori z več primeri. Glavne teme dodatka, ki ji članek obravnava, so Rufinova uporaba Evzebijevega koncepta apostolskega nasledstva, njegovo zanimanje za biografije vidnih kristjanov, za herezije, trpljenje Judov, pogansko preganjanje ter za širitev krščanstva tako znotraj kot zunaj meja rimskega cesarstva. V povezavi s tem se prispevek posveča predvsem pokristjanjenju tujih poganskih ljudstev in boju proti poganstvu v rimskem Egiptu ter Italiji. V celoti gledano je Rufinov dodatek v dveh knjigah v svojem bistvu precej drugačen od Evzebijeve Cerkvene zgodovine. Namesto neprestanega navajanja virov, ki daje Evzebijevemu delu avreolo objektivnosti in pristnosti, je Rufin svoj dodatek v večji meri osnoval na ustnih virih. Poleg tega izkazuje globoko zanimanje za čudeže, zaradi česar je dodatek prava zakladnica najrazličnejših čudežev, ki so jih v 4. stoletju izvršili kristjani. Opise čudežev Rufin izkoristi za to, da vedno znova pokaže, kako je gibalo zgodovinskega dogajanja dejansko krščanski Bog, ki poskrbi, da pravoverni kristjani premagajo heretike in pogane.
Sallust and Jean Bodin
Authors: Pobežin Gregor
Published: January 2023

One of the most recognizable thinkers of the 16th century France, Jean Bodin, wrote what is perhaps the first methodological treatise of instructions and guidelines on how to not only read and write but also understand history. With his universal interest in all things human, Bodin predated Marc Bloch’s postulate that historians should ideally be interested in all forms of life if they were to perform their task as dutifully as possible. In 1566 Bodin published one of the most frequently reprinted works, the Methodus ad facilem historiarum cognitionem – “The Method for the Easy Understanding of History”. Although he expressed keen interest and good knowledge of a score of ancient historians, listing them in the fourth chapter of his work (De historicorum delectu – “On the Choice of Historians”), one of them was particularly close to his heart. The Roman historian Gaius Sallustius Crispus who is, according to Bodin, “a most honest author [who] possessed experience of important affairs”, provided Bodin and many of his colleagues with a model (stasis) narrative for discussing a changing world in turmoil – something Bodin was no stranger to in the time of the French religious wars. However, the explanation that it was the rhetorically efficient model narrative that inspired Bodin to copy Sallust’s argument seems unsatisfactory and biographically superficial. Instead, this paper closely analyses the Sallustian chapters that purportedly motivated Bodin’s thinking and proposes that there are little grounds in Sallust for Bodin’s legal and historical framing of absolutist sovereignty.
A Deep Learning-Based Utilization Improvement Framework for Abdullah Hashim Industrial Gases & Equipment Co. Ltd Transportation Network
Authors: H. Nayef A. Balbaid , A F. Neama Noor
Published: January 2023

Transportation disruption causes economic loss in supply chains in the gas industry while population growth increases, which calls for a comprehensive review of the operations by management. Hence, the gas company should study and evaluate the situation and make the right decision by taking corrective action to minimize the negative impact of disruption. This paper aims to develop a deep learning-based model to improve the efficiency of the constrained transportation network of an industrial gas company in conjunction with historical data. The framework was demonstrated using an example case of the gas industry in Jeddah, Saudi Arabia. The findings revealed the usefulness of the Wilde Neural Network model in classifying the trip cost with an accuracy of 100% and a short duration of training of 2.84 seconds.
Características clínicas y evolución de la infección por SARS-CoV-2 en pacientes con lupus eritematoso sistémico en Argentina: datos del registro nacional SAR-COVID
Authors: Isnardi Carolina Ayelén , Roberts Karen , Tissera Yohana , Petkovic Ingrid , Berbotto Guillermo , Gobbi Carla , Tanten Romina , Cogo Karina , Asnal Cecilia , Baños Andrea , Vivero Florencia , Schmid María Marcela , Lázaro María Alicia , German Noelia , Takashima Lorena , Scafati Julia , Werner Marina Laura , Casalla Luciana , Matellan Carla , Castrillon Diana M. , Rodríguez Florencia , Moyano Sebastián , Martín María Luz , Cosentino Vanesa , Herscovich Natalia , Tralice Elda R. , Barbich Tatiana , Vásquez Dora L. , Buschiazzo Emilio , Maid Pablo , Ledesma Ana C. , Yohena Víctor , Gómez Gimena , Quintana Rosana , Pons-Estel Guillermo J.
Published: January 2023

Introducción: el lupus eritematoso sistémico (LES) es una enfermedad sistémica que se ha asociado a mayor severidad con la infección por SARS-CoV-2. Particularmente la alta actividad de la enfermedad y algunos inmunosupresores se han vinculado a peores desenlaces.

Objetivos: describir las características por SARS-CoV-2 en pacientes con LES en Argentina del registro SAR-COVID y establecer los factores asociados a peor desenlace de la misma.

Materiales y métodos: estudio observacional. Se incluyeron pacientes con diagnóstico de LES con infección confirmada por SARS-CoV-2 (RT-PCR y/o serología positiva) del registro SAR-COVID. Los datos se recolectaron desde agosto de 2020 hasta marzo de 2022. El desenlace de la infección se midió mediante la escala ordinal de la Organización Mundial de la Salud (EO-OMS). Se definió COVID-19 severo con un valor EO-OMS ≥5. Análisis descriptivo, test T de Student, U de Mann Whitney U, ANOVA, chi2 y Fisher. Regresión logística múltiple.

Resultados: se incluyeron 399 pacientes, el 93% de sexo femenino, con una edad media de 40,9 años (DE 12,2). El 39,6% tenía al menos una comorbilidad. Al momento de la infección, el 54,9% recibía glucocorticoides, el 30,8% inmunosupresores y el 3,3% agentes biológicos. La infección por SARS-CoV-2 fue leve en la mayoría de los casos, mientras que un 4,6% tuvo curso severo y/o falleció. Estos últimos presentaban comorbilidades, usaban glucocorticoides y tenían síndrome antifosfolípido (SAF) con mayor frecuencia y mayor actividad de la enfermedad al momento de la infección. En el análisis multivariado, la hipertensión arterial, el diagnóstico de SAF y el uso de glucocorticoides se asociaron a hospitalización severa y/o muerte por COVID-19 (EO-OMS ≥5).

Conclusiones: en esta cohorte de pacientes con LES con infección por SARS-CoV-2 confirmada, la mayoría cursó de manera sintomática, un 22,1% fue hospitalizado y un 5% requirió ventilación mecánica. La mortalidad fue cercana al 3%. El diagnóstico de SAF, tener hipertensión arterial y el uso de glucocorticoides se asociaron significativamente con COVID-19 severo.
EFFECT OF STRUCTURED NURSING INTERVENTIONS ON SELECTED MATERNAL PARAMETERS AMONG CAESAREAN MOTHERS
Authors: thomas Mrs. Vincy , Starlin Mrs. C. Prabha
Published: January 2023

A study was conducted to assess the effect of structured nursing interventions on selected maternal parameters among mothers undergone lower segment caesarean section at M.G.M Hospital, Kalamboli, Navi Mumbai. A quasi-experimental research approach and Pretest-posttest control group design was adopted. The 50 samples were selected using Nonprobability convenient sampling technique. The instrument used for the data collection procedure was Observation checklist for measuring comfort of mother, Standardized Numerical pain rating scale, Standardized breast-feeding LATCH scale and Brief Modified Pain Inventory
Telemedicine Development for Health Center Services Using Agile Methods
Authors: Lahru Riatma Darmawan , Masbahah Masbahah , Megasari Anis Laela , Fatsena Rizka Adela
Published: January 2023

Puskesmas are the spearhead of health services throughout Indonesia, puskesmas are at the forefront in breaking the chain of transmission of COVID-19 because they are located in every sub-district and have a regional concept. Being at the forefront in handling COVID19 and continuing to provide other primary health services to the community is a tough task for puskesmas throughout Indonesia. In urgent situations and rapidly changing regulations regarding the handling of COVID19 and non-COVID19 patients, telemedicine application development researchers are required to work quickly and precisely according to the needs of the Puskesmas. This study discusses the development of telemedicine applications using the Agile development method, with the Scrum framework. Based on the problems above, researchers will develop telemedicine applications with several health service features, namely; COVID19 independent health checks, village doctor and midwife consultations, medicine orders, maternity services, and dental consultation services, the features in the telemedicine application were developed using the agile scrum method. Telemedicine development begins with system design analysis, UI/UX design, develop, functional testing, usability testing and launching. From the system design analysis, it produces output use case diagrams and class diagrams, according to the needs of the puskesmas business process. UI/UX design is carried out using figma tools, then application development is carried out focusing on the frontend and backend, after the application has been developed, functional testing is carried out three times and usability testing. The results of the usability test conducted on 35 respondents obtained an average score through the SUS questionnaire with a score of 79. In terms of the Acceptability Range, this application program is in the Acceptable category, while on the Grade Scale it is in Grade C position and on the Adjective Rating it is in a Good position . The results show that the telemedicine application for Pusline is good and can be accepted by users.
UPAYA UNITED NATIONS MISSION IN SOUTH SUDAN DALAM MELINDUNGI KORBAN CONFLICT-RELATED SEXUAL VIOLENCE PADA KONFLIK SUDAN SELATAN
Authors: Talitha Nabila  , Retno Susilowati  , Indra Tamsyah
Published: January 2023

Penelitian ini bertujuan untuk mengetahui bagaimana upaya aktor internasional United Nations Mission in South Sudan dalam melindungi korban Conflict-Related Sexual Violence pada konflik Sudan Selatan. Maraknya laporan kasus CRSV di Sudan Selatan mendesak organisasi internasional UN memberi mandat kepada UNMISS agar melakukan misi operasi perdamaian untuk melindungi warga sipil dan membangun perdamaian yang berkelanjutan. Penelitian ini dikaji menggunakan konsep Gender Sensitive Conflict Analysis (GSCA). Metode penelitian yang digunakan penulis adalah metode kualitatif deskriptif dengan tujuan menjelaskan fenomena secara dalam melalui langkah-langkah analisis data dengan memanfaatkan konsep sebagai bahan penjelasan. Data yang dikumpulkan penulis melalui studi literatur, penelusuran data daring, dan dokumentasi. Hasil penelitian menunjukkan bahwa UNMISS telah berhasil melakukan upaya perlindungan terhadap korban CRSV melalui upaya analisis kontekstual, interseksionalitas, dan partisipatif. Hal ini dapat dilihat dari menurunnya jumlah kasus dan angka korban serta banyaknya apresiasi warga sipil atas kerja keras UNMISS.
Ecología y biotecnología aplicadas al manejo sostenible del agave en Sonora
Authors: Esqueda Valle Martín Candelario , Coronado Andrade Martha Lizett , Gutiérrez Saldaña Aldo Hiram , Robert Díaz Manuel Luis , Bañuelos Flores Noemí , Barraza Morales Alejandra , Fragoso Gadea Tania , Franco Martínez Irma Sonia , García Mendoza Abisaí Josué , Gardea Béjar Alfonso Antero , Martínez Ramón Francisco Javier , Sánchez Teyer Lorenzo Felipe , Méndez Ramírez Ignacio , Millán Soto Gabriela , Ochoa Meza Andrés , Orozco Avitia Jesús Antonio , Palomino y Hasbach María Guadalupe Antonia , Ramos Clamont Montfort Gabriela , Salido Araiza Patricia Lorenia , Sandoval Gutiérrez Daniel , Vargas Rosales Georgina , Vázquez Moreno Luz , Verdugo Figueroa Leonardo
Published: January 2023

Esta obra presenta el conocimiento generado sobre la biología, ecología y biotecnología del complejo Agave angustifolia, con la participación interdisciplinaria e interinstitucional de investigadores. Brinda a los productores una opción de manejo sostenible del agave con un aprovechamiento diversificado e integral. La micropropagación puede generar las cantidades requeridas de plantas para cultivos, forestación y/o recuperación de poblaciones silvestres. Para el trasplante en áreas naturales se valida un modelo holístico con base en los factores bióticos y abióticos del sitio. Esta alternativa biotecnológica es viable, por el costo razonable de las vitroplantas, el porcentaje de prendimiento alto y el manejo 100 % orgánico sin riegos, fertilizantes ni plaguicidas. Se promueve el uso del agave como fuente de fibra a través de la biomasa foliar, el bagazo del tallo para la generación de bioenergía, los fructanos en prebióticos de humanos y animales, y el rescate del conocimiento ancestral como alimento y medicinal. Elementos esenciales Describe una alternativa biotecnológica para el manejo sostenible del agave a través de la micropropagación y el trasplante holístico en áreas naturales Restablece y circunscribe Agave pacifica para Sonora Explica los estudios citogenéticos y de variabilidad génica en poblaciones silvestres Esclarece la importancia de las plantas nodrizas y los hongos promotores de crecimiento en el establecimiento exitoso del agave Destaca la aplicación de la calorespirometría como un método de selección temprana de agaves altamente productivos Coedición con Editorial Fontamara, S.A. de C.V.
Estudio de factibilidad para una microempresa de asesoría y venta de insumos para huertos familiares en Delicias, Chihuahua
Authors: Sánchez-Aguirre Javier Alejandro , Terrazas-Gómez Marina Imelda , Baray-Guerrero María Del Rosario , Villarreal-Ramírez Víctor Hugo , Aguirre-Avilés Edmundo José
Published: January 2023

En el proyecto de estudio de factibilidad para una microempresa de asesoría y venta de insumos para huertos familiares en Cd. Delicias, Chihuahua se logró desarrollar un plan de factibilidad económica de la empresa, de publicidad y comercialización de huertos familiares. Como primer paso se realizó un estudio de mercado dirigido a la población de Cd. Delicias, Chihuahua en donde la muestra fue de 400 jefes de familia encuestados. Una vez obtenida esta información se realizaron gráficas y análisis de datos para determinar la aceptación del producto y servicio; se realizó un análisis de competencia con tres empresas de la ciudad dando como resultado una ventaja competitiva derivada de la  calidad del producto y la completa variedad que se ofrece para que las familias puedan complementar su dieta alimenticia diaria, además de la adaptación de este a las necesidades del cliente sumado al precio accesible que la empresa ofrece con posible asesoría a mediano plazo para el cuidado oportuno de su producto. Se procedió a la creación de misión, visión, valores, metas organizacionales, distribución de la planta, así como una matriz FODA y el estudio de rentabilidad (TIR, VAN, beneficio-costo y punto de equilibrio) para la posible creación de la microempresa.
KEPEMIMPINAN SPIRITUAL KH. ABDUL GHOFIR NAWAWI DALAM MENUMBUHKAN KEHIDUPAN MODERASI BERAGAMA
Authors: Astutik Dian , Al-Habsyi Ni’ma M. , Polamolo Fika Magfirah
Published: January 2023

This study aims to uncover the spiritual leadership of a Kyai in fostering religious moderation. The method used is descriptive qualitative with a phenomenological approach with primary and secondary data sources. Data collection techniques are observation, interviews, and documentation. Data analysis techniques consist of data collection, data reduction, data presentation, and drawing conclusions. The results showed that spiritual leadership, K.H. Abdul Ghofir Nawawi, among others, has been implemented at the Salafiyah Syafi'iyah Randangan Gorontalo Islamic Boarding School, namely: attitude honesty of heart in fostering religious moderation, Faimes attitude in fostering religious moderation, and humility in fostering religious moderation
IMPLEMENTASI PEMBELAJARAN PENDIDIKAN AGAMA ISLAM TERHADAP PENINGKATAN JIWA NASIONALISME PESERTA DIDIK DI KABUPATEN SORONG
Authors: Yunita Dina Suci , Abdillah M Fardan
Published: January 2023

This study aims to determine the effect of the implementation of Islamic education learning on increasing the spirit of nationalism of students in Sorong Regency. This study uses quantitative research with a quantitative associative approach. The population of all students who are Muslim in Sorong Regency. Sampling was carried out at SMP Negeri 26 Sorong Regency from class VII-IX. thoroughly by conducting population research with a total of 38 students. Data collection was carried out by distributing questionnaires and analyzing using a simple regression test. The results of this study indicate that the implementation of Islamic Religious Education Learning affects increasing the spirit of nationalism of students in Sorong Regency. This can be seen from the results of a simple regression test with the equation Y = 31,888+.727+e with a constant value of 31,888, and the value of the regression coefficient of Islamic religious education learning is 0.727
KONTROL DIRI DAN PERSEPSI TERHADAP IKLIM SEKOLAH DENGAN PERILAKU BULLYING PADA SISWA
Authors: Dwi Prasetya Fiki Febrian
Published: January 2023

The rise of bullying cases in schools is very worrying, especially for victims who often receive bullying committed by their own friends. Individuals who often receive bullying at school experience a number of psychological disorders such as anxiety, loneliness, feeling worthless and feeling unacceptable by their peers. Each individual has a mechanism that can help regulate and direct behavior called self-control. The purpose of this study was to determine the relationship between self-control and perceptions of school climate with bullying behavior. Subjects totaled 205 junior high school (SMP) students, sampling using purposive sampling technique. The data collection method used is a Likert scale instrument which has been tested for validity and reliability with Cronbach's Alpha coefficient of self-control 0.904, school climate 0.949 and bullying behavior 0.961. The data obtained were analyzed using regression analysis. The results showed that there was a relationship between self-control and perceptions of school climate with bullying behavior, the F value was 121.059 (p <0.01), so the third hypothesis was accepted. The effective contribution of self-control and school climate perceptions to predict bullying behavior in students was 54.5%, while the remaining 45.5% was influenced by other factors which were not examined in this study. This research is expected to be useful in knowing what predictors are the factors that have a relationship with bullying behavior, so that it can be used as a reference for taking intervention actions to reduce bullying behavior in students
Application of Iterative Three-Dimensional Laplace Transform Method for 2-Dimensional Nonlinear Klein-Gordon Equation
Authors: Deresse Alemayehu Tamirie
Published: January 2023

In the present study, the exact analytical solutions of the 2-dimensional nonlinear Klein-Gordon equation (NLKGE) is investigated using the 3-dimensional Laplace transform method in conjunction with the Daftardar-Gejji and Jafari Method (Iterative method). Through this method, the linear part of the problem is solved by using the 3-dimensional Laplace transform method, while the noise terms from the nonlinear part of the equation disappear through a successive iteration process of the Daftardar-Gejji and Jafari Method (DJM), where a single iteration gives the exact solution to the problem. Three test modeling problems from mathematical physics nonlinear Klein-Gordon equations are taken to confirm the performance and efficiency of the presented technique. For each illustrative example, the convergence of the novel iterative approach is shown. The findings also suggest that the proposed method could be applied to other types of nonlinear partial differential equation systems.
HIGHLIGHTS

Partial differential equations play a crucial role in the formulation of fundamental laws of nature and the mathematical analysis in different fields of studies
The Klein-Gordon equation (KGE) is a nonlinear hyperbolic class of partial differential equations that occur in relativistic quantum mechanics and field theory, both of which are crucial to high-energy physicists
The 3-dimensional Laplace transform method provides rapid convergence of the exact solution without any restrictive assumptions about the solution for linear differential equations
The Laplace Transform method is often combined with other methods like the Daftardar-Gejji and Jafari (the new Iterative) method to solve complicated nonlinear differential equations
The new iterative technique yields a series that can be summed up to get an analytical formula or used to build an appropriate approximation with a faster convergent series solution

GRAPHICAL ABSTRACT
Educación emocional y bienestar: por una práctica científicamente fundamentada
Authors: Bisquerra Alzina Rafael , Chao Rebolledo Cimenna
Published: January 2023

La educación emocional, también conocida como educación socioemocional, es una respuesta a necesidades sociales que no están suficientemente atendidas en el currículo ordinario. Tiene como objetivo el desarrollo de competencias emocionales o socioemocionales, con la intención de mejorar el bienestar personal y social. Desarrollar y educar de forma explícita estas competencias puede tener un impacto altamente positivo en diversos ámbitos de la vida. La educación emocional se sustenta en las investigaciones científicas que desde la década de los noventa analizan y definen fenómenos asociados con la inteligencia emocional, las inteligencias múltiples, la neurociencia, la psicología positiva, y la pedagogía humanista, entre otros campos de la psicología y la educación. Para que la puesta en práctica de la educación emocional sea eficiente, se requiere poner en marcha una serie de requerimientos organizacionales y pedagógicos que se refieren a lo largo de este trabajo.
Review on Social Media and Digital Security
Authors: Yahya Hussien Amar
Published: January 2023

The emerging social media with inherent capabilities seems to be gaining edge over comprehensiveness, diversity and wisdom, nevertheless its security and trustworthiness issues have also become increasingly serious, which need to be addressed urgently. The available studies mainly aim at both social media content and user security, including model, protocol, mechanism and algorithm. Unfortunately, there is a lack of investigating on effective and efficient evaluations and measurements for security and trustworthiness of various social media tools, platforms and applications, thus has effect on their further improvement and evolution. To address the challenge, this paper firstly made a survey on the state-of-the-art of social media networks security and trustworthiness particularly for the increasingly growing sophistication and variety of attacks as well as related intelligence applications. And then, we highlighted a new direction on evaluating and measuring those fundamental and underlying platforms, meanwhile proposing a hierarchical architecture for crowd evaluations based on signaling theory and crowd computing, which is essential for social media ecosystem. Finally, we conclude our work with several open issues and cutting-edge challenges.
Pharmaceutical Sales and Marketing
Authors: Mr. Ajay Bhagawan Lawate  , Dr.Monika Shinde  , Dr. S. K. Bais
Published: January 2023

Market relationships and rivalry are developing in the pharmaceuticals sector. defines the need for the main marketing provision's characteristics and scientific, deliberate use in the context of population drug supply. Pharmacies and pharmaceutical companies' marketing strategies help them respond effectively to environmental changes, consumer expectations, and organisational skills for market research and analysis-based management decisions. From the planning stage and product development to after-sales service and the examination of the consumer's response to it, marketing has a broad range of applications. When entering a foreign market, marketing is crucial to boosting exports
Epidemiological characteristics of ankylosing spondylitis in Guangxi Province of China from 2014 to 2021
Authors: Sun Xuhua , Zhou Chenxing , Chen Liyi , Huang Shengsheng , Ye zhen , Yi Ming , Liao Shian , Li Hao , Jiang Jie , Chen Jiarui , Chen Wuhua , Chen Tianyou , Guo Hao , Zhang Shiqing , Zhu Jichong , Liang Tuo , liu Chong , Zhan Xinli
Published: January 2023

Introduction

To explore the epidemiological characteristics of ankylosing spondylitis (AS) in Guangxi province of China through a large sample survey of more than 50 million aborigines population .

Material and methods

A systematic search was conducted using the International Classification of Diseases 10 (ICD-10) codes M45.x00(AS), M45.x03+(AS with iridocyclitis), and M40.101(AS with kyphosis) to search the database in the National Health Statistics Network Direct Reporting System (NHSNDRS). 14004 patients were eventually included in the study. The parameters analyzed included the number of patients, gender, marriage, blood type, occupation, age at diagnosis, and location of household registration data each year, and statistical analysis was performed.

Results

AS incidence rates increased from 1.30 (95% CI 1.20–1.40) per 100,000 person-years in 2014 to 5.71(95%CI 5.50-5.92) in 2020 in Guangxi Province, and decreased slightly in 2021. Males have a higher incidence than females, the ratio was 5.61:1. The AS incidence rate was disparate in different cities. Liuzhou city was the highest that the eight-year average AS incidence rates from 2014 to 2021,and Chongzuo city was the lowest( p＜0.05).There was no significant difference in the incidence between different ethnic groups(p＞0.05).

Conclusions

The AS person-years incidence rate was increasing in Guangxi province of China from 2014 to 2020, which had obvious gender and regional differences, showing the characteristics of local area aggregation.
Bünting verlängert mit Vorstandschef
Authors: Preuschat Christiane , Hofmann Janine
Published: January 2023

Der Aufsichtsrat von Bünting hat den Vertrag von Markus Buntz um fünf Jahre verlängert. 2023 will der norddeutsche Händler angesichts der allgemeinen Kaufzurückhaltung die Kosten weiter senken.
Reh-Kendermann in großem Dilemma
Authors: Murmann Christoph
Published: January 2023

Die Weinkellerei Reh-Kendermann hat 2022 empfindliche Rückschläge im Markengeschäft erlitten. Handelseinkäufer und Konsumenten kaufen in der Wirtschaftskrise vermehrt Discountware. Die für Februar erwartete Erhöhung der Ladenpreise droht die Marktsituation zu verschärfen.
„Der Bio-Fachhandel hat auch ein Qualitätsthema“
Authors: Krost Heidrun
Published: January 2023

Frisches Obst und Gemüse war im Jahresverlauf 2022 nur wenig von der Inflation betroffen. Bei Bioware jedoch musste mancher Händler einen Dämpfer hinnehmen, denn auch eingefleischte Biokäufer kaufen immer öfter günstig und im Discount. Die Sorge ist groß, dass Bio als Qualitätsstandard unter die Räder kommt. Denn aktuell sind Preisanpassungen bei Biogemüse unumgänglich, sagt Rainer Carstens, Geschäftsführer und Inhaber bei Westhof Biogemüse.
Vilsa beschleunigt in der Logistik
Authors: Bökamp Lena
Published: January 2023

Mit der Inbetriebnahme des neuen Hochregallagers werden die Logistikprozesse beim Mineralbrunnen Vilsa schneller. Eine wichtige Rolle spielt dabei auch eine bessere Softwaresteuerung – im Lager wie auch bei der Tourenplanung.
„Die Food-Branche kann sich nicht zurücklehnen“
Authors: Hübner Marco
Published: January 2023

Die Entwicklung des Metaverse wird keine zehn bis 15 Jahre in Anspruch nehmen. Der Lebensmittelindustrie und -handel rät Mark Wächter deshalb, das Thema anzugehen. Wächter leitet das Ressort Metaverse im Bundesverband Digitale Wirtschaft und erklärt, welche Themen für Unternehmenslenker wichtig werden.
NURSING CARE FOR CHILDREN WITH PEDIATRIC MULTISSYSTEMIC INFLAMMATORY SYNDROME
Authors: De Lucena Viana Alves Letícia , Gilvandra de Souza Dantas Walkiria , Carolina Salustino Maria , Allyson Gomes Ferreira Jefferson , Rodrigues Pereira Patrícia , De Castro Cardoso Jéssica , Gomes de Souza Silva Lúcia
Published: January 2023

Objective: to evidence from the scientific literature the clinical and therapeutic characterization of children with Pediatric Multisystem Inflammatory Syndrome and definition of their respective diagnostic diagnoses; Method: the study is configured as a scope review, it is organized by the Preferred Reporting Items for Systematic Review and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) in which it is proposed by the Joanna Briggs Institute; Results: 34 articles were identified after a sample in the databases, and after the selection of data inclusion and exclusion of 16 final articles; Final considerations: Nursing care for children and adolescents with SIM-P is still unexplored and has limited scientific evidence. In addition, nurses should be aware of updates on a thorough clinical assessment, including anamnesis, physical examination, epidemiological link with suspected or confirmed cases of COVID-19 in the 2nd to 4th week prior, in addition to Complementary tests to assess the process. inflammation and the recovery of organs, to early identification and treatment, having as vital functions.