bluuebunny/crossref_metadata_2025 huggingface dataset:
Goal-setting improves motivation in first-episode psychosis
Authors: Fulford Daniel , Meyer-Kalos Piper S. , Mueser Kim T.
Published: December 2019

Introduction: Diminished motivation (e.g., low drive, curiosity, and engagement in activities) is associated with robust impairment in psychosocial functioning in schizophrenia, yet even the most effective evidence-based interventions rarely effect meaningful change in motivation. Individual Resiliency Training (IRT) is a psychosocial treatment for individuals following a first episode of psychosis, supporting motivation through recovery goal setting and pursuit. The extent to which such an approach might improve motivation over time is unknown.Method: We tested the impact of exposure to IRT modules focused on goal setting and attainment on motivation and functional outcomes among participants in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP). In the sample of 404 individuals with a first episode of psychosis receiving treatment across 34 community sites, we ran mixed-effect models with group (exposed to four or more goal-focused IRT sessions vs. Community Care (CC)), time (baseline, six- and 12-month follow-up), and the group-by-time interaction as predictors of motivation, role and social functioning. We also ran these analyses with those exposed to three or fewer goal-focused IRT sessions compared to CC.Results: Controlling for gender, ethnicity, baseline cognition, and total number of outpatient mental health visits, exposure to four or more goal-focused IRT sessions was associated with greater improvements in motivation and role functioning compared to CC; effects were not observed for social functioning. Participants receiving three or fewer goal-focused IRT sessions did not differ from those in CC in these outcomes. Further, sensitivity analysis showed that general exposure to IRT was not associated with differential outcomes.Conclusions: Findings suggest that sufficient focus on recovery goal setting and support in psychosocial intervention for first-episode psychosis may have specific impact on motivation.
Score revisado de trauma como predictor de mortalidad en accidentes de tránsito
Authors: Escobar Suárez Carlos Antonio , Terán Bejarano María José , Orozco Noboa María Fernanda , Yupangui Tenesaca Darwin Quintelmo , Rea Quinllay José Raúl , Lozano Caicedo Jennifer Elizabeth , Chávez Enríquez Graciela Viviana , Villegas Tapia Esteban Marcelo
Published: December 2019

Introducción:La presente investigación se basa en la aplicación de la escala Revised Trauma Score (RTS) basada en escala Glasgow, frecuencia respiratoria y presión arterial sistólica que pronostica de acuerdo al cálculo de puntuación posibilidad de mortalidad en pacientes atendidos por accidentes de tránsito en el Servicio de Emergencia del Hospital General Latacunga, Enero – Marzo 2017.

Objetivo: Aplicar la escala RTS para mejorar la calidad de la atención de pacientes con trauma

Metodología: Se realizó un estudio descriptivo prospectivo, cuali-cuantitativa no experimental y transversal, utilizando como instrumentos de investigación fichas con la información de historias clínicas y hojas 008 de Emergencia..

Resultados: La muestra calculada fue 87 pacientes; de los cuales 64,3% correspondió al género masculino predominando las edades entre 19 a 59 años. El mayor porcentaje de lesiones fue trauma de cabeza (30%), seguido miembros superiores-inferiores (23%). La puntuación de la escala RTS demostró 31% tenían traumas severos que necesitaron atención inmediata. En Emergencia la mortalidad fue 32%, demostrando su alta incidencia en los accidentes de tránsito.

Conclusiones: La escala RTS es un buen predictor de mortalidad, ayuda al manejo médico y facilita la aplicación de guías clínicas para traumatizados, evitando substraje y sobretriaje, con atención médica inmediata.
Apendicitis aguda en paciente con situs inversus totalis
Authors: Villagómez Yánez Cristian Manuel , Asquel Cadena Víctor Hugo , Moreno Caballeros Evelyn Nataly , Ganchala Padilla Marcia Karina
Published: December 2019

Introducción: El situs inversus totalis y la apendicitis aguda izquierda son afecciones poco frecuentes, su prevalencia, se estima de 1 /10.000 nacimientos, la relación hombre mujer es de 1.5:1. 

Objetivo: Describir un caso clínico de de situs inversus totalis con apendicitis aguda.

Material y métodos: Se realizó un estudio descriptivo, retrospectivo, presentación de caso clínico de situs inversus totalis con apendicitis aguda.

Resultados: Se presenta el caso de un paciente masculino de 41 años, que ingresó en el Servicio de Cirugía del Hospital del Instituto Ecuatoriano de Seguro Social de Latacunga, el mismo refirió dolor de gran intensidad localizado en fosa iliaca izquierda, en el examen físico se constataron signos clínicos de abdomen agudo inflamatorio en esta zona. Los estudios de imágenes confirmaron el diagnóstico de situs inversus totalis y de apendicitis aguda izquierda. En la cirugía se comprobó la situación del apéndice cecal en fosa iliaca izquierda, apendicitis aguda perforada y peritonitis, realizándose apendicectomía, limpieza y secado de la cavidad abdominal más colocación de drenaje. Evolucionó satisfactoriamente, fue egresado al quito día, sin complicaciones postoperatorias.

Conclusiones: En todo paciente con sospecha de situs inversus y/o apendicitis aguda izquierda se recomienda realizar una tomografía, prueba radiológica de elección para el diagnóstico de estas afecciones, cuya sensibilidad es aproximadamente de 93 % y especificidad del 98 %. Las opciones de tratamiento para la apendicitis del lado izquierdo son las mismas que en los casos de localización habitual, puede realizarse apendicetomía abierta o laparoscópica. El abordaje laparoscópico es viable y útil para valorar diagnósticos diferenciales y resolver distintas patologías coexistentes
Síndrome de Herlyn-Wener-Wunderlich
Authors: Barreno Sánchez Diana Fernanda , Paguay Carrasco Luis Geovanny , López Mariuxi
Published: December 2019

Introducción: El Síndrome de Herlyn-Wener-Wunderlich es una malformación de los conductos de Müller y de Wolf, debido a una falta de fusión de los mismos, es muy rara y se caracteriza por presentar un útero didelfo, con una hemivagina obstruida y agenesia renal ipsilateral, más frecuente del lado derecho.

Objetivo: Describir un caso clínico de una paciente adolescente con cuadro de dismenorrea secundario a Sindrome de Herlyn-Wener-Wunderlich.

Material y métodos: Se realizó un estudio descriptivo, retrospectivo y documental sobre dismenorrea secundaria, malformaciones mullerianas y presentación de un caso clínico.

Resultados: Se describe el caso de una paciente de 13 años tratada en la Unidad Materno Infantil del Hospital Teodoro Maldonado Carbo, con cuadro de dismenorrea severa desde el inicio de la menarca, presenta masa pélvica dolorosa a la palpación, se realiza ecografía abdominal y pélvica encontrando dos tumoración de contenido líquido con sedimento que se extienden hasta canal vaginal y que compromete cérvix bilobulado, la ecografía abdominal reporta ausencia de riñón derecho por lo que fue sometida a laparotomía exploratoria confirmando el diagnóstico de malformación uterina con útero didelfo, hemivagina derecha ciega y hematocolpos. 

Conclusiones: Las malformaciones Mullerianas corresponde a anomalías congénitas poco comunes y el Síndrome de Herlyn-Wener-Wunderlich es una entidad mucho menos común, causante de cuadros de dismenorrea severa, abdomen agudo, su diagnóstico clínico es difícil y requiere estudios complementarios. El tratamiento es conservador con el fin de preservar la función reproductiva de la paciente
Pseudoaneurisma femoral
Authors: Feijoó Diana , Herdoíza Gino , Padilla Lorena , Suarez Leon Ricardo Sebastian
Published: December 2019

Introducción: Los pseudoaneurismas.son como un hematoma pulsátil repermeabilizado y encapsulado, en comunicación con la luz de un vaso dañado. La diferencia entre pseudoeaneurisma y aneurisma radica en que este último está formado histológicamente por todas las capas arteriales. Todos los pseudoaneurismas tienen en común la rotura de la pared arterial con extravasación de sangre dentro de los tejidos que rodean la arteria, el resultado es la formación de una cápsula de tejido fibroso que crece progresivamente debido a la presión arterial. Se presenta un caso clínico de lesión vascular inadvertida, por trauma penetrante en muslo izquierdo atendido en el área de emergencia y cirugía, valorada como una herida simple a la cual se le realizó una limpieza quirúrgica y sutura de la misma, incluso para los médicos en el primer contacto pasaron por alto el daño vascular ya que presentaba pulsos distales, la lesión posteriormente se presentó con edema de muslo y masa pulsátil palpable la cual necesito resolución de manera quirúrgica debido a la gravedad de la lesion en la pared arterial; también requirieron resección y bypass con vasos nativos. El pseudoaneurisma como lesión vascular suele pasar inadvertida, es necesario educar a los médicos de primer contacto en la búsqueda de esta patología cuando se presentan antecedentes de trauma. Los auxiliares diagnósticos (ultrasonido, arteriografía, angioTAC) son necesarios para la confirmación diagnóstica y planeación quirúrgica. El mayor tiempo de evolución se relaciona con mayor dificultad técnica para la resolución del problema.

Objetivo: Describir el caso clínico de un paciente con pseudoaneurisma femoral.

Material y métodos: Estudio descriptivo retrospectivo, presentación de caso clínico.

Resultados: Se presenta el caso clínico de un paciente de 23 años, con lesión vascular inadvertida, por trauma penetrante en muslo izquierdo atendido en el área de emergencia y cirugía como una herida simple a la cual se le realizó una limpieza quirúrgica y sutura de la misma, incluso para los médicos durante el primer contacto no se percataron del daño vascular ya que presentaba pulsos distales, la lesión posteriormente se presentó con edema de muslo y masa pulsátil palpable la cual necesito resolución de manera quirúrgica debido a la gravedad de la lesion en la pared arterial; también requirieron resección y bypass con vasos nativos.

Conclusiones: Toda lesión traumática debe ser considerada de alta probabilidad de lesión vascular hasta que se demuestre lo contrario, con una adecuada historia clínica y cinemática del trauma, identificación del tipo de lesión, exámenes de laboratorio, imagenología para un tratamiento oportuno y evitar el pseudoaneurisma que es la principal complicación de un mal manejo inicial.
Creando cultura científica
Authors: Recalde-Navarrete Ricardo Javier
Published: December 2019

La formación continua en los profesionales que ejercen actividades docentes en las Instituciones de Educación Superior (IES) permite tener talento humano competente, actualizado y convencido del ser, del debe ser y del deber hacer; para lograr los objetivos institucionales que aportan al desarrollo de su contexto social.

Las IES desde el 2014 han estado inmersas en una serie de reformas que buscan el desarrollo social, económico y educativo; El Consejo de Educación Superior (CES) ejerce su rectoría en los ámbitos Académicos, de Gestión, Investigación y Vinculación con la sociedad.

Las instituciones educativas deberán contar con líneas, programas y proyectos de investigación que vinculen a su personal académico con redes nacionales e internacionales, con el objetivo de generar conocimientos, que respondan a los planes regionales y locales de desarrollo en los campos de la educación superior, la ciencia y la tecnología.

La Universidad Técnica de Ambato (UTA) realiza investigación formativa y generativa científica tecnológica y social que permite generar innovación tecnológica, crecimiento productivo y rescate de lo social que contribuya a la superación de problemas mas prevalentes en el ámbito de la salud publica en concordancia con los planes de desarrollo del Ecuador y del mundo, bajo los principios de calidad, pertinencia, integridad, autodeterminación para la producción del pensamiento y conocimiento. En el contexto referido, la Facultad Ciencias de la Salud (FCS) y la Coordinación de Investigación organizaron en el año 2015 el “I Congreso de Investigación en Ciencias de la Salud” como estrategia que respondiera a las directrices institucionales, de los entes de control en educación y a los planes de desarrollo local y regional.

Para el 2019 se realizará la cuarta edición y se observa como evolucionó la estrategia al brindar espacios de capacitación cíclica, dialogo permanente con investigadores nacionales e internacionales de reconocido prestigio, la difusión del conocimiento científico en revistas de impacto mundial y regional que generan los investigadores a través de la docencia,  en la práctica profesional en el ámbito de la salud, en la ejecución de los proyectos de investigación, al involucrar a los estudiantes en la generación de productos científicos.

La investigación está en evolución permanente, con un número creciente de producción científica y de  proyectos de investigación que contribuyen a brindar soluciones a los problemas prioritarios de la sociedad, en la acreditación de las carreras, que tienen como uno de los ejes principales la investigación científica, sumado al empleo de las Nuevas Tecnologías del Aprendizaje y la Comunicación, que facilitan la difusión del conocimiento científico y sobre todo del talento humano que es el motor impulsor del progreso Institucional
Pengaruh Audit Tenure, Komite Audit Dan Ukuran Perusahaan Terhadap Kualitas Audit (Studi Empiris Pada Perusahaan Food & Beverage yang Terdaftar di BEI Periode 2014-2017
Authors: Oentoro Vannesa Paramitha , Aprilyanti Rina
Published: December 2019

Arah penelitian ini bertujuan untuk mengetahui apakah audit tenure komite audit dan ukuran perusahaan mempunyai pengaruh terhadap kualitas audit secara parsial maupun simultan pada perusahaan Food & Beverage yang terdaftar di Bursa Efek Indonesia periode 2014 â€“ 2017. Pembuktian hipotesis dalam penelitian ini menggunakan metode analisis linier berganda untuk mengetahui pengaruh secara parsialnya dan metode omnimbus untuk mengetahui pengaruh secara simultannya. Hasil penelitian secara parsial menunjukkan bahwa, audit tenure dan komite audit tidak berpengaruh terhadap kualitas audit sedangkan ukuran perusahaan berpengaruh terhadap kualitas audit. Sedangkan secara keseluruhan atau simultan semuanya berpengaruh terhadap kualitas audit
Is isometrics effective on pain perception, functional mobility and anxiety of geriatric clients with osteoarthritis at Pathanamthitta District, Kerala
Authors: Nisha M.D.
Published: December 2019

Background: Osteoarthritis is a major cause of many medical conditions and disability in people above 50’s and leads to reduced activity in older people. Global statistics revels that over 100 million people worldwide suffers from Osteoarthritis.

Materials and methods: A quasi experimental pretest - posttest control group design was used. 200 geriatric clients with osteoarthritis residing in selected geriatric homes at Pathanamthitta were selected and assessed by using a Numerical Pain Intensity Scale, an Observational check list and a three point rating scale for pain, functional mobility and anxiety.

Results: There was a significant difference between the mean pain score( t = 10.758 p = 0.01, df – 198), functional mobility ( t = 7.73 p = 0.01, df – 198) and anxiety (t = 7.665 ,df –198, p=0.01in experimental and control group after intervention ( t = 10.758 p = 0.01, df – 198).Statistically no significant association was found between pain, functional mobility and anxiety with variables such as gender, religion, marital status, number of children’s and duration of stay.The pain and anxiety correlation value was ‘r’ = 0.89. The functional mobility and anxiety correlation value was ‘r’ = 0.80. The functional mobility and pain correlation value was ‘r’ = 0.83. It shows that statistically positive correlation is present between the geriatric clients’ pain and anxiety, functional mobility and anxiety and functional mobility and pain at p<0.05% level of significance.

Conclusion: Exercise is one of the best methods to treat Osteoarthritis. This study proved that isometric exercises are beneficial to improve the functional mobility of joints in old age people. When the mobility increases, intensity of joint pain decreases.
Relationship between fasting blood glucose and body mass index among students of a medical college
Authors: Vargese Saritha Susan , Joseph T.M. , Mathew E.
Published: December 2019

Background: Obesity is one of the most important modifiable risk factors in the pathogenesis of lifestyle diseases like atherosclerosis, hypertension and type 2 diabetes mellitus. Overweight or obese adolescents are at an increased risk of developing diabetes and hypertension in future. A study was done to determine the relationship between body mass index and fasting blood glucose among students of a tertiary care teaching hospital.

Materials and methods: A cross sectional analytical study was carried out among all medical students in a tertiary care teaching hospital in Kerala who consented to participate after obtaining approval from Institutional Research and Ethics Committee. The study tools used were standardized weighing machine, stadiometer, Accu-check glucometer and strips, disposable needles and pre-designed questionnaire.

Results: Among the 254 study participants, 67% were females. The prevalence of impaired fasting glucose is 18.11% in the study population. No significant correlation was found between fasting blood glucose and body mass index. There was an increase in median FBS as the BMI increases, though not statistically significant (p=0.08). In the linear regression model, the statistic R2 explains that 7.9% of the variability in fasting blood glucose is explained by body mass index.

Conclusion: The prevalence of prediabetes among the study participants was very high and it was higher among those who were overweight. The need of the hour is to identify the high-risk group in the community right from the young age and initiate trials or intervention studies to prevent or delay the onset of diabetes.
Attitude Towards Replacement of Missing Teeth Among the Patients Visiting Nobel Medical College and Teaching Hospital
Authors: Rathi Ankita , Chhetri S
Published: December 2019

Introduction: Teeth play a significant part in the maintenance of a healthy personality and an affirmative self-image. Tooth loss is psychologically a very traumatizing and upsetting experience, and is considered to be a serious event in the life of a person, requiring significant psychological readjustment.

Objective: Evaluate the prosthetic status and attitude of the patients towards replacement of the teeth among the patients visiting dental department, Noble Medical College and Teaching Hospital (NMCTH)

Materials and Methods: A cross sectional study was conducted over a duration of 6 months to determine prosthetic status and attitude of the patients towards replacement of the teeth among all patients visiting Department of prosthodontics, NMCTH. The inclusion criteria was all patients with at least one missing tooth (excluding third molars) and subjects who gave consent for the study. All the Patients were provided with six close ended questionnaire followed by clinical examination by a well trained investigator.

Result: The total number of participants was 297. Of them 157 were male and 140 were female. Most frequently encountered age group was 21-30 years Of these, 80.8% of individual were provided with proper information about replacement of teeth whereas 19.2 % were not. 70.7% individual said they will replace only when they find difficulty in their daily activities. 64.6 % of individual wanted to replace teeth for appearance, 20.5% for function and 14.8% for both appearance and function. 79.5 %stated financial problem and 18.2% stated lack of awareness regarding not replacement of teeth.

Conclusion: The patients’ attitudes and demand towards the replacement of missing teeth might be different from the clinicians’ assessment. We consider factors such as the preservation of natural teeth and the maintenance of periodontal health as priority but patients tends to prioritize comfort in mastication and improvement of esthetics. Therefore, it is vital to investigate patients’ awareness, need and demand on prosthodontic treatment options.
Knowledge, Attitude and Practice of Tooth Morphology among the Dentists of Kathmandu
Authors: Chaulagain Rajib
Published: December 2019

Background: Dental anatomy is taught as a basic dental subject in dental schools of Nepal. The knowledge has immense use in clinical practice in dentistry. However, few people feel that it has no use and should be removed from the dental curriculum. The objective of the study was to analyze the knowledge, attitude and practice of tooth morphology among dental practitioners in Kathmandu.

Materials and Methods: A cross-sectional study was undertaken among the dental practitioners in Kathmandu using a self-administered questionnaire to collect the data. In total 300 questionnaires were distributed. The results were analysed for descriptive statistics using the Statistical Package for the Social Sciences (SPSS) 16 software.

Results: A total of 249 responses from the dental practitioners were received. In total 77.9 % of participants strongly agreed that understanding tooth morphology helped in identification of primary and permanent teeth. More than 90% had positive response regarding its use in day to day clinical practice.

Conclusion: The present study revealed that the dental practitioners have adequate knowledge of tooth morphology and agree on its importance in professional dental practice.
Clinical Complications of Beta-Thalassemia Major
Authors: Shawkat Ali Jalal , H. Jwaid Ahmed
Published: December 2019

Beata thalassemia

Beta thalassemia syndrome by reduction or absence of B-globin chain synthesis. Without iron chelation therapy (ICT) the regular blood transfusion would increase the iron stores to several times. Endocrine glands are vulnerable to iron overload causing endocrine dysfunction.  Iron deposition within the parathyroid gland causes hypoparathyroidism particularly after ten years of age. Pancreatic islets are very susceptible to oxidative damage due to iron overload; their high divalent metal expression makes them highly susceptible to iron-catalyzing oxidative stress. The pathogenicity of osteopathy in  is multifactorial comprising environmental (diet and lifestyle), iatrogenic (medicines), genetic and acquired factors (expansion of bone marrow, hemochromatosis, deficiency of growth hormone, hepatitis and hypogonadism).The increase in blood transfusion and RBCs break down in addition to iron accumulation and deposition are the main factors causing splenomegaly. Liver disease is one of the major complications affecting patients with B TM.Liver damage is multifactorial with iron overload is considered the main causative factor, as well as hepatitis C (HCV) and hepatitis B (HBV) infections which are acquired on recurrent blood transfusions. The free radicals of deposited iron overcome the cellular antioxidant mechanisms resulting in peroxidative cellular injury. As a result, iron overload is the leading cause of left ventricular cardiomyopathy development
EFECTOS DEL EXTRACTO DE β -CARIOFILENO DE PIPER NIGRUM EN LA HIPERACTIVACIÓN ESPERMÁTICA Y EN LA CAPACIDAD FECUNDANTE DE TETRAPYGUS NIGER (MOLINA, 1782) ‘‘ERIZO NEGRO DE MAR’’
Authors: Zapata Daniela , Wixsan Joyce , Hinostroza Katherine , Justo Santiago , Gonzales-Figueroa Hugo
Published: December 2019

En el presente trabajo se analizó la hiperactivación espermática y la capacidad fecundante del espermatozoide de Tetrapygus niger (Molina, 1782) “erizo negro de mar” en presencia de β-cariofileno. Se utilizó el sesquiterpeno β-cariofileno obtenido a partir de extracto de Piper nigrum L. “pimienta negra” y de β-cariofileno sintético donado por el Instituto de Biociencias de la Universidad de Sao Paulo (Sao Paulo, Brasil). Espermatozoides de Tetrapygus niger pretratados con los extractos de β-cariofileno sintético (β-cariofileno A) y β-cariofileno de pimienta negra (β-cariofileno B) fueron utilizados para la hiperactividad espermática (velocidad media y porcentajes de movimiento progresivo y continuo) y la capacidad fecundante (porcentaje de óvulos fecundados). Los valores promedios del área de la cabeza del espermatozoide en el control y en los tratamientos con β-cariofileno A y β-cariofileno B fueron de: 33,8; 32,33 y 33,59 um2, respectivamente, indicando la homogeneidad en la muestra y que esta no fue influenciada por el sesquiterpeno. En presencia de β-cariofileno A y B se observó la disminución de la velocidad promedio en aproximadamente 30 y 20 um/s, respectivamente, con respecto al control; existiendo diferencias significativas entre el control y los tratamientos con β-cariofileno A y B, pero no entre los dos tratamientos con β-cariofileno. El movimiento progresivo de los espermatozoides también fue afectado, mientras la totalidad de los espermatozoides del grupo control presentaron progresividad rápida, en el tratamiento con β-cariofileno B solo el 40 % presentaron esta característica y en el tratamiento con β-cariofileno A el 100 % fueron progresivos lento. Por otro lado, el β-cariofileno B produjo una ligera disminución de fecundación (96,76 % de óvulos fecundados) y en presencia de β-cariofileno A, esta se redujo a 79,50 % con respecto al grupo control. Un posible mecanismo para explicar los efectos observados en este estudio sería la capacidad del β-cariofileno para activar proteínas G inhibitorias, como ha sido reportado en otros estudios.
Preliminary study on pre-treatment physical activity and quality of life in infertility
Authors: Prémusz Viktória , Makai Alexandra , Gács Boróka , Nagy Ágnes , Perjés Beatrix , Ács Pongrác , Lampek Kinga , Várnagy Ákos
Published: December 2019

The increasing incidence of infertility and contrary the remaining levels of success rate of assisted reproductive therapies (ART) justify expanding the biomedical approach and underline the importance of psychosocial and lifestyle factors. The aim of the study was to examine the effects of pre-treatment physical activity (PA) on the quality of life (QoL) in infertile women. A cross sectional cohort study was carried out involving 50 female patients with infertility diagnosis. Standardized QoL questionnaires and pre-treatment PA patterns were administrated during December 2018 – April 2019 in a university hospital-based fertility centre in South-Hungary. 43% of the women reported regular exercise. Regarding GPAQ moderate intensity PA in work and recreation was preferred. They spent 4.2 hours with active transportation weekly, and 4.5 hours sedentary daily. 68.89% reached the 150min/week MVPA recommendation and 18.2% spent more than 4 hours with exercise Respondents were less satisfied with Physical Domain (57.7±7.5) and most with Psychological Domain (72.2±12.1) of WHOQOL-BREF. Lower QoL by Emotional (56.46±18.12) and Mind-Body (56.84±19.67), mediate by Social (62.76±17.40) and better values by Relational Subscale (76.48±19.62) were measured with FertiQoL. Significant difference between active and inactive group was described for Psychological domain (Z=-2.240, p=0.025). Positive correlation was found between MVPA vs Total MET and Emotional Subscale (p=0.014, p=0.009) and between work-related PA and Mindbody Subscale (p=0.006). Pre-treatment PA could positively affect QoL undergoing ART. However, for more impressive results, objective assessment of physical activity, increased number of participants, and further examinations are needed.
ENERGY SAVING TECHNOLOGIES FOR DRYING OF HEAT-SENSITIVE MATERIALS
Authors: Sniezhkin Yu.F. , Jian Xiong , Chalaev D.M. , Ulanov М.М. , Dabizha N.О.
Published: December 2019

The promising development of convective drying of thermolabile materials is the use of heat pumps. The main advantages of heat pump drying are high energy efficiency, controlled thermal conditions of drying, high quality of the final product, environmental cleanliness of the technological process.The processes of air treatment in convective heat pumps with different schemes of dehydration of the drying agent are considered in the paper. As determined, the main disadvantage of heat pump drying is the long duration of the process due to the drying temperature limitation not exceeding 50-60 °C, and the dried material is not initially heated above the temperature of the wet thermometer, which is 25-30 °C. The possibility of using infrared radiation in combination with a heat pump was studied to intensify the process of low-temperature convective drying. It is shown that the combination of heat pump and infrared drying processes provides a synergistic effect, which leads to a shorter drying time and reduced energy consumption, as well as to obtain better quality dried products.
TECHNICAL ANALYSIS OF PRODUCTS OF USED TIRES THERMOCHEMICAL CONVERSION
Authors: Sklyarenko E.V. , Vorobiov L.Y. , Kirzhner D.A. , Plashykhin S.V.
Published: December 2019

Introduction. Utilization of worn tires in the world is of great economic and ecological importance for all developed countries. This is due to the fact that worn tires are a source of long-term pollution of the environment by toxic components and a causative agent of the sanitary-epidemiological situation in their places of storage.

Today, the most common method for disposing of tires is to burn them to produce energy that requires special technologies and combustion plants and exhaust gas cleaning systems. In addition, the disadvantage of this method is the increased CO2 emissions.

One of the promising ways to dispose of tires is the technology of full carbon recycling by means of a preliminary thermochemical conversion, the result of which is the physico-chemical transformation of the organic part of the raw material into new gaseous, liquid and solid carbon-based energy products that can be used in the industry. In order to reduce the cost of transporting worn tires to large processing enterprises, promising is developing mobile thermochemical conversion units, which can carry out the processing of tires in places where they accumulate.

The main way to control the quality of the products obtained is to determine their calorific value, by calorimetric and technical analysis.

The purpose of the work is to determine the thermal characteristics of samples of pyrolysis of worn tires in a mobile conversion plant and to evaluate their potential use for energy purposes.

Research results. The humidity, ash content and heat of combustion of raw materials in the form of crushed rubber of worn tires and products of its pyrolysis - liquid fuel and solid carbon have been investigated. High and net heat of combustion of analytical sample, fuel in dry state and in working condition of delivery is determined using the data of experimental measurements, taking into account corrections for the formation of sulfuric and nitric acid. The value of the net heat of combustion in the state of delivery for the crushed rubber of tires, liquid and solid pyrolysis products, respectively, amounted to 30.36; 40.79; 24.37 MJ / kg.

Conclusion. The conducted studies showed high energy characteristics of the studied samples, which can be used as alternative fuels. The use of pyrolysis products does not require special installations. Their combustion can be carried out in existing installations without significant reconstruction.
Mechanisms and Functional Significance of Human Tumor-infiltrating Myeloid Cells
Authors: Ramezani Amin , Toghraie Fatemeh Sadat
Published: December 2019

Myeloid cells as the major components of tumor-infiltrating leukocytes play critical roles in anti-tumor immunity. However, emerging evidences have revealed that soluble factors produced by tumor/stromal cells skew myeloid cells toward a tumor-promoting phenotype. Tumor-infiltrating myeloid cells (TIMs) including tumor-associated macrophages (TAMs), tumor-associated neutrophils (TANs), myeloid-derived suppressor cells (MDSCs), and tumor-associated dendritic cells (TADCs) are considered as the key mediators of tumor microenvironment (TME). TIMs have been shown to play important roles in various aspects of cancer biology and their presence is often linked to altered patient prognosis and survival. Regarding their critical role in TME, TIMs have been proposed as relevant targets of therapeutic strategies aimed at expanding immunostimulatory myeloid cell populations and depleting or modulating immunosuppressive ones. In this review, we briefly describe TIMs subsets and discuss the mechanisms by which TIMs induce immunosuppression, angiogenesis, and metastasis.
Ters Yüz Sınıfa Yönelik Gerçekleştirilen Çalışmaların Eğilimleri: Bir Sistematik Alanyazın Taraması
Authors: ÖZBAY Özkan , SARICA Rabia
Published: December 2019

Ters yüz sınıf modeli, sınıf içi ve sınıf dışı etkinliklerin yerini
değiştiren bir öğrenme yaklaşımıdır. Bu yaklaşımda öğrenenler ders içeriğini sınıf
dışı teknolojik uygulamalar aracılığıyla öğrenmekte, sınıf içinde ise daha
fazla uygulama yapmaktadırlar. Son yıllarda bu yaklaşıma olan ilgi giderek
artmaktadır. Bu araştırmada, ters yüz sınıf modeliyle ilgili yapılan
çalışmaların çeşitli açılardan incelenerek ulaşılan sonuçların ortaya konulması
amaçlanmıştır. Bu doğrultuda ters yüz sınıf modeline ilişkin Web of Science ve
Google Akademik veri tabanları üzerinde belirlenen ölçütler doğrultusunda
sistematik bir alanyazın taraması gerçekleştirilmiştir. 2014-2019 yılları
arasını kapsayacak şekilde gerçekleştirilen alanyazın taraması sonucunda,
erişilen ve araştırma kapsamına alınması uygun bulunan toplam 64 makale çalışma
grubu, araştırma yöntemleri, ters yüz sınıf modelinin uygulanmasında kullanılan
teknolojiler, çalışmaların gerçekleştirildiği konu alanları ve bu çalışmalarda
ele alınan konular açısından betimsel içerik analiz yöntemi kullanılarak
incelenmiştir. Analiz sonucunda ters yüz sınıf çalışmalarının en çok lisans
düzeyindeki öğrenenler ile yabancı dil eğitimi konu alanında gerçekleştirildiği
görülmüştür. İncelenen çalışmalarda, nicel araştırma yöntemlerinin daha çok
tercih edildiği belirlenmiştir. Ayrıca çalışmalarda akademik başarı, öğrenci
katılımı, öğrenci görüşleri, öğretmen görüşleri ve motivasyon konularının sıklıkla
incelendiği görülmüştür. Ortaya konulan bulguların ters yüz sınıf modelini
temel alacak yeni çalışmalara çeşitli açılardan ışık tutacağı düşünülmektedir.
2018 Türkçe Dersi Öğretim Programı Kazanımlarının 21. Yüzyıl Becerileri Açısından İncelenmesi
Authors: KURUDAYIOĞLU Mehmet , SOYSAL Taşkın
Published: December 2019

Bu
çalışmanın amacı, 2018 yılında güncellenen Türkçe Dersi Öğretim Programı  (1-8. Sınıf) kazanımlarının 21. yüzyıl
becerilerinin yaşam ve kariyer becerileri; öğrenme ve yenilikçilik becerileri;
bilgi, medya ve teknoloji becerilerine uygunluğu açısından incelenmesidir.
Araştırmada öğretim programında (MEB, 2018) yer alan her bir kazanım söz konusu
becerilere uygunluğu bakımından incelemeye tabi tutulmuştur. Araştırma nitel olarak desenlenmiştir. Çalışmanın verileri
doküman analizi yoluyla toplanmıştır. Buna göre öğretim programındaki 524 ayrı kazanım
her bir beceriye uygunluğu açısından incelenmiştir. Sonuç olarak
öğrencilerimizin çağın ihtiyaçlarına cevap verebilen, her geçen gün gelişen
dünyaya ayak uydurabilecek donanımlı bireyler olmaları bakımından önem arz eden
21. yüzyıl becerilerine, güncellenen 2018 programına bağlı kazanımlarda yeterli
ve dengeli düzeyde yer verilmediği görülmüştür.

Anahtar
sözcükler: 21. yüzyıl becerileri, öğretim programı, kazanım,
Türkçe eğitimi.
The commonly accepted statement (το ομολογουμενον) as a starting point for a theological discussion – Eunomius and Gregory of Nyssa
Authors: Przyszychowska Marta
Published: December 2019

During the debate between Eunomius and Gregory of Nyssa as a basic and irrefutable argument both parties to the conflict used the statement that the the­ses they promoted were commonly accepted. Both of them defined the commonly accepted statement with the Greek term tÕ ÐmologoÚmenon which in the philo­sophical tradition derived from Aristotle meant true and reliable premiss that led to absolute knowledge. In such a meaning that term – interchangeably with the expression koinaˆ oennoiai – was used not only in philosophy but also in rhetoric. The methods used by Eunomius and Gregory of Nyssa show that their dispute was not what we would today call a religious issue, but a truly scientific/philosophical debate conducted in accordance with the commonly accepted (nomen omen!) rules.
From abstraction to unsaying: how the Eunomian controversy changed Gregory of Nyssa’s aphairetic ethics to an apophatic ethics
Authors: Steenbuch Johannes Aakjær
Published: December 2019

In early Christian thinking negative theology was often applied for polemi­cal purposes, as a means of asserting the Christian distinction between God and everything else. Only later did negative theology develop into a philosophical and contemplative method. But even then it often kept a polemical function. This was the case for Gregory of Nyssa who applied forms of negative theology in his spiritual and exegetical works as well as in his polemical works, especially those against Eunomius. Using a distinction between aphairetic and apophatic kinds of negative theology, it can be argued that Gregory’s theology, epistemology and philosophy of language, as developed during the Eunomian controversy, changed his negative theology in a fundamental way from an aphairetic theology, based on abstraction, to a thoroughly apophatic theology, based on negation in the sense of unsaying. It can further be argued that the results of this development influenced Gregory’s ethical theories, his moral epistemology in particular. The main texts in question, besides Gregory’s writings against Eunomius, are his early work on the inscriptions of the Psalms and his later work on the life of Moses. Both contain reflections on Moses’ spiritual development, but while the former uses mostly affirmative language, the latter involves a much higher degree of apophatic theo­logy. This change is likely to have occurred during the Eunomian controversy where such things as God’s infinity and the inability of human beings to grasp the divine essence became fundamental in such a way that apophatic, rather than aphairetic, language and thinking gained a central role in Gregory’s theology as well as ethics.
Inimici nostri: Jews as heretics and heretics as judaizers in Jerome and Augustine
Authors: Hood John Y.B.
Published: December 2019

In their polemical as well as their ostensibly non-polemical writings, SS. Jerome and Augustine refer to the Church’s enemies as an unholy triad: Jews, pagans, and Christian heretics. These inimici, they assert, are linked by their com­mon failure to accept the Gospel of the orthodox Catholic Church, as well as by the root cause of their unbelief: pride, which leads them to resist the truth. In this article, I focus on the links Jerome and Augustine purport to find between Judaism and Christian heresy. I draw from polemical and non-polemical works by both writers, including Jerome’s biblical commentaries and anti-Pelagian treatises, and Augustine’s De Civitate Dei as well as his writings adversus Jews, Donatists, and Pelagians. In addition to identifying the doctrinal commonalities that Jerome and Augustine assert exist between Judaism and Christian heresy, I examine the often-similar rhetorical devices employed by both writers in their denunciations of these inimici. The article concludes by speculating on the possible roots of these denunciations in the authors’ doubts and insecurities, and notes that, para­doxically, Jerome and Augustine’s epistemological doubts regarding divine elec­tion led them to retain a measure of hope for their theological enemies, and so to counsel tolerance toward them.
Eretici ed eresie nel Chronicon di san Girolamo
Authors: Degórski Bazyli
Published: December 2019

Kontynuując Chronicon Euzebiusza z Cezarei, wśród wielu innych postaci św. Hieronim wymienia także błędnowierców i odszczepieńców IV w. Wskazuje przy tym częstokroć na ich związki z walką polityczną i władzą świecką, która w owym czasie nękała prawowiernych chrześcijan, czyniąc z nich swoistych „mę­czenników”. Donatyści, arianie, macedonianie (duchobórcy), eunomianie, aecja­nie, audianie, fotynianie nie uniknęli surowej oceny wielkiego Ojca Kościoła, który niekiedy – ograniczony swoistym, krótkim stylem samej Kroniki – nawet poprzez jeden jedyny przymiotnik wyraża całą swoją krytykę i dezaprobatę wzglę­dem błędnowierców oraz tych, którzy ich wspierali i im schlebiali. Nieustanne walki o czystość wiary nie zawsze kończyły się zwycięstwem, jak to widać np. w postanowieniach synodów z Rimini i Seleucji. Niemniej jednak przekaz fak­tów, dokonany przez Hieronima, pozwala czytelnikowi poznać choćby w zarysie przebieg i cały niesprzyjający kontekst polityczny tych teologicznych sporów. Po raz kolejny lektura faktów i ich kontekstu historyczno-politycznego potwierdza, iż rozłamy i trudności wewnątrz Kościoła pierwszych wieków były spowodowa­ne działaniami zewnętrznymi władz świeckich, wykorzystującymi ludzką słabość spragnioną raczej władzy niż prawdy.
„Non intelligis stultitiam tuam impudentiae copulatam”. Św. Hieronim contra Pelagiusz
Authors: Jóźwiak Magdalena
Published: December 2019

Reading the ancient scriptures of Christians of the first centuries, one can easily notice numerous invectives. From among the Fathers of the Church there are three who in particular deserve the title of “fathers of Christian invectives”. One of those who best can be described as such is St. Jerome of Stridonius. It should not come as a surprise, because in ancient times one did not reach only for intellectual arguments when defending their views. A logical elucidation was merely a part of argumentation. The other part, of no less importance, were arguments ad homi­nem, including also invectives. Verbal insults were integral part of argumentation and the lack of them would decrease the value of debate. In this article, based on St. Jerome’s of Stridonius writings, I portrayed his reactions to the phenomenon of pelagianism, as well as to the person of Pelagius himself. This subject has been analysed in many articles, but I presented it from a different angle. Namely, I em­phasized varied interesting invectives that St. Jerome – well-known for his sharp tongue – directed to Pelagius, basing on argumentum ad personam.
L’insegnamento “ereticale” sulla visione di Dio nelle opere di Giuseppe Hazzāyā, mistico siro-orientale del secolo VIII
Authors: Havrylyk Ihnatia
Published: December 2019

W historii Asyryjskiego Kościoła Wschodu (Kościół tradycji wschodniosyryj­skiej) VIII w. stał się okresem rozwoju mistyki monastycznej. Jednym z wielkich nauczycieli duchowych tego okresu był Józef Hazzāyā, który dokonał syntezy nauki poprzedników. Fundament jego twórczości stanowi nauka o kontemplacji Boga, która była obca dla tradycji Antiocheńskiej i dlatego została potępiona jako heretycka przez patriarchę Tymoteusza I na synodzie w latach 786-787. W ar­tykule dokonano analizy nauki Józefa o kontemplacji Boga w celu krytycznego spojrzenia na podstawy jego potępienia. Autorka przeprowadziła analizę termi­nów, które Józef stosuje na określenie stanu kontemplacji Boga, a także przedsta­wiła specyfikę jego nauczaniu w tej kwestii. W ostatnim punkcie artykułu został przedstawiony krótki zarys chrystologii Kościoła Wschodu oraz nauka dotycząca doświadczenia w sferze kontemplacji Boga.
Rola eunuchów na dworze cesarzy bizantyńskich. Przypadek Narzesa
Authors: Malinowski Rajmund
Published: December 2019

The article is divided into two sections. First presents the role of eunuchs in Byzantine Empire in general. Second section focuses specifically on Narses, his life, main achievements and legacy. The term eunuch (eÙnoàcoj) is ambiguous. It generally refers to people who are not able to procreate due to natural constitution or mutilation, but it can have many various meanings. It can also refer to the man who is absent from procreation due to impotence or celibate. For people who has been born incapacitated or with some hormonal anomalies we use term „natural eunuchs”. There were several functions of eunuchs in Byzantine state we can differentia­te. First is religious. Eunuchs were present in institution of Church from the very beginning. They could have been priests and patriarchs if they did not become eunuchs as a result of self-mutilation. Many eunuchs were high officials at the court of Byzantine emperors. They served as envoys, agents and as a members of palace guard. They were also responsible for superintending of the emperor’s son. And finally, eunuchs were successful and talented military leaders. Life of Narses is fascinating example of a great career of eunuch in Byzantine Empire. He owes his success to his many talents and sympathy and protection of the emperor Justinian and his wife Theodora. He came to Constantinople from east, probably as a slave. At the beginning, he was a low rank official at the court. He also served as a member of the palace guard. Thanks to his intelligence and flexibility he became chamberlain at the court. Later he got a generalship of By­zantine army in Italy. He was called back to the capital, after he got involved in conflict with great general Belisarius. Several years later, however, Justinian once again used his skills to finally crush Ostrogoth’s army. He spent his last years of life as governor of conquered land.
Islamic Boarding School and Community Empowerment
Authors: Sulisno Sarwadi , Abdullah Azis
Published: December 2019

Islamic education has contributed since before independence. As a long journey requires a spirit that can guide and support to get to the point of success at any time. Mental entrepreneurship can provide the spirit of education to be able to disrupt itself in order to be able to exist with all the challenges of globalization in the digital era. Mental entrepreneurship is a skill that does not only make things from nothing and makes some things from some other things, but also the ability to see and predict the challenges of current and futuristic challenges, then do disruption either by reshape old one -Create a new one to the existing pattern. Entrepreneurship ability will be formed after soft skill entrepreneurship abilities are possessed by students. Until the peak of entrepreneurship of Islamic edication was to view disruption as an opportunity to lead to a new Islamic education.