bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: The First Enantioselective Syntheses of Pure (R)‐ and (S)‐Isoproterenol.
Authors: COREY E. J. , LINK J. O.
Published: May 2016

Starting with the substituted acetophenone (I), the (R)‐(‐)‐isoproterenol (VIII) is synthesized.
ChemInform Abstract: A Novel Procedure for the Synthesis of Ether‐Bridged Perfluoro Non‐Ionic Surfactants.
Authors: SELVE C. , ACHILEFU S. , MANSUY L.
Published: May 2016

The polyethylene glycols (I) are selectively monobenzylated and then activated by tosylation.
ChemInform Abstract: Efficient Method for the Preparation of Z‐α‐Alkoxy β,γ‐Unsaturated Nitriles Starting from the Corresponding Acetals of E‐Chalcone Derivatives.
Authors: MUKAIYAMA T. , TAKENOSHITA H. , YAMADA M. , SOGA T.
Published: May 2016

The acetals (I) of unsaturated ketones react with trimethylsilyl cyanide (II) to give mixtures of the stereoisomeric 2‐methoxy‐3‐butenenitrile derivatives (III) and (IV).
ChemInform Abstract: Trifluoromethylthio‐ and Pentafluorophenylthio‐substituted Alkenes and Arylalkenes.
Authors: KONDRATENKO N. V. , KHOMENKO L. A. , YAGUPOL'SKII L. M.
Published: May 2016

The reactions between copper trifluoromethyl sulfide (IIa) or copper pentafluorophenyl sulfide (IIb) and the five differently substituted alkenes (I), (IV), (VI), (VIII) and (X) afford the title compounds (III), (V), (VII), (IX) and (XI).
ChemInform Abstract: Metacyclophanes and Related Compounds. Part 26. Tetrahydroxy(2.n.2.n)metacyclophanes. Preparation, Reactions, and Spectra.
Authors: TASHIRO M. , TSUGE A. , SAWADA T. , MAKISHIMA T. , HORIE S. , ARIMURA T. , MATAKA S. , YAMATO T.
Published: May 2016

Reaction of the dianisylalkanes (I) with formaldehyde (II) and HCl gives the chloromethylation products (III) which are converted into the dithiols (IV) upon treatment with thiourea.
ChemInform Abstract: Reaction of Pyrocatechol and Hydroquinone with Bromo‐ and Hydroxyadamantane.
Authors: MIRYAN N. I. , YURCHENKO A. G. , KIRIENKO E. I.
Published: May 2016

Pyrocatechol (I) is coupled with 1‐bromoadamantane (II) in the presence of boron trifluoride etherate to give the mono‐ (III) or diadamantylpyrocatechol (IV) depending on the molar ratio.
ChemInform Abstract: Regioselective Cyclopropanation via Unsymmetrical Oxatrimethylenemethanepalladium Intermediates.
Authors: TROST B. M. , URABE H.
Published: May 2016

The carbonates (I) react with the silyl triflates (II) to give the silyl enol ethers (III) and (IV) with predominance of (III).
ChemInform Abstract: The Synthesis of Butenolide α‐Formyl Acetals.
Authors: CHAN K. , SANNER M. A. , CARLSON R. M.
Published: May 2016

3‐Phenylthio‐2‐(phenylthiomethyl)propenoic acid (III), prepared by a known procedure, is converted to the symmetrical dianion salt (V) which is coupled and cyclized with the carbonyl compounds (VI), forming the methyl‐γ‐lactones (VII).
ChemInform Abstract: Thermal 1,6‐Electrocyclization Reactions of Acceptor‐Substituted 2,3‐Divinyl‐1H‐indoles Yielding Functionalized Carbazoles.
Authors: PINDUR U. , ADAM R.
Published: May 2016

New synthetic procedures including the title reaction leading to functionalized carbazoles such as (III) or (VIII) are described.
ChemInform Abstract: Second Generation Single‐Chain Cleavable Surfactants.
Authors: JAEGER D. A. , SAYED Y. M. , DUTTA A. K.
Published: May 2016

The methyl octadecenoate, prepared from the acid (I), is reduced and then substituted to form the mesylate (IV) which is converted to the ammonium salt (VI).
ChemInform Abstract: Synthesis and Physical Studies of Azamitosene and Iminoazamitosene Reductive Alkylating Agents. Iminoquinone Hydrolytic Stability, syn/anti‐Isomerization, and Electrochemistry.
Authors: ISLAM I. , SKIBO E. B.
Published: May 2016

Catalyzed by ZnCl2, the pyrrolidinobenzene (I) is cyclized to give the benzimidazole (III).
ChemInform Abstract: Stereospecific Syntheses of erythro‐ and threo‐(1′,2′‐Dihydroxyethyl)‐3‐aryloxazolidin‐2‐ones.
Authors: GENET J. P. , DENIS A. , VILAR A. , SCHOOFS A. R. , ALARD P.
Published: May 2016

Starting with cis‐1,4‐dichloro‐2‐butene (II) or trans‐1,4‐dibromo‐2‐butene (VII), the stereoisomeric epoxy carbamates (V) and (IX) are prepared.
ChemInform Abstract: New Synthesis of 1,2,4‐Oxadiazoles.
Authors: YAROVENKO V. N. , TARALASHVILI V. K. , ZAVARZIN I. V. , KRAYUSHKIN M. M.
Published: May 2016

The interaction of amidoximes such as (I) with nitriles such as (II) in the presence of a catalyst and HCl affords the 1,2,4‐oxadiazoles (III).
ChemInform Abstract: New Direct Synthesis of 3‐Nitro‐2H‐chromenes Using Nitroethylene.
Authors: AL NEIRABEYEH M. , KOUSSINI R. , GUILLAUMET G.
Published: May 2016

The 2‐hydroxybenzaldehydes (I) undergo cyclocondensation with nitroethylene (II) in the presence of dibutylamine to form the nitrochromenes (III) mentioned in the title.
ChemInform Abstract: Synthesis of 2‐Cyclopropylchromones Under Phase‐Transfer Catalysis Conditions.
Authors: RAO D. M. S. , RAO E. V. S. B. , RAO A. V. S.
Published: May 2016

The cyclocondensation of the dihydroxyacetophenones (I) with cyclopropanecarboxylic chloride (II) is best performed under phase‐transfer catalysis, forming the 2‐cyclopropylchromones (III).
ChemInform Abstract: Synthesis of 3‐(3‐Benzofuranyl)coumarins.
Authors: DESHPANDE A. R. , PARADKAR M. V.
Published: May 2016

The o‐hydroxyacetophenones (I) are brominated at the side chain and then cyclized to yield the benzofuranones (III).
ChemInform Abstract: Synthesis of 2,4‐Diamino‐thieno(2,3‐d)pyrimidines.
Authors: LINK H.
Published: May 2016

In the course of studies concerning the preparation of dihydrofolate reductase inhibitors, the title compounds (Va) and (Vb) are synthesized; MCPBA oxidation of (Va) leads to the corresponding sulfoxide in 46% yield.
ChemInform Abstract: Unusual Amination by Cleavage of an Exocyclic C‐N Linkage with Formamide.
Authors: RAM V. J. , KUSHWAHA D. S.
Published: May 2016

Starting from the 2‐hydrazinoquinazolinones (I) and (VI), a series of seven 2‐(1‐pyrazolyl)‐quinazolinones such as (III) and (VIII) are prepared according to A).
ChemInform Abstract: Stereochemical Studies. Part 145. Saturated Heterocycles. Part 152. Preparation and Conformational Analysis of Stereoisomeric 1,6,7‐11b‐Tetrahydro‐2H(1,3)oxazino(4,3‐a)isoquinolin‐4‐one Derivatives.
Authors: LAZAR L. , FUELOEP F. + , DOMBI G. , BERNATH G. , ARGAY G. , KALMAN A.
Published: May 2016

The known tetrahydroisoquinoline (I) is converted to some trifunctional derivatives such as (III).
ChemInform Abstract: Porphyrins and Their Derivatives. Part 11. Porphyrins Containing an Oxyethylenic Chain.
Authors: MEL'NIK V. I. , ZHILINA Z. I. , ANDRONATI S. A. , MAMONTOV V. P.
Published: May 2016

The reaction between the porphyrin derivative (I) and large excesses of the diols (II) yields the new monoethers (III), which are reacted with a second equivalent of (I) to give the hitherto unknown dimeric porphyrin derivatives (IV), which differ in their steric orientations.
ChemInform Abstract: Synthesis and Biological Activity of Bromides of ω‐(Dimethyltriorganylsilylmethylammonio)alkanoic Acids.
Authors: PISARSKII YU. B. , VVEDENSKII V. YU. , VORONKOV M. G. , KAZIMIROVSKAYA V. B. , KISHKINA I. M. , VASIL'EVA N. N. , MOSKVITINA L. T.
Published: May 2016

The ω‐bromoalkanoic acid trimethylsilyl esters (II) react with the triorganylsilylmethyldimethylamines (I) to give the ammonioalkanoic acids (III) after methanolysis.
ChemInform Abstract: Heptasila(7)paracyclophane.
Authors: ANDO W. , TSUMURAYA T. , KABE Y.
Published: May 2016

The title compound (II), the first example of an (n)paracyclophane with heterometal bridges, is obtained by reductive coupling of (I) with Na in the presence of the crown ether (important to avoid polymeric products).
ChemInform Abstract: Synthesis and Reactivity of 1,1‐Disodio‐2,3,4,5‐tetraphenyl‐1‐silacyclopentadiene.
Authors: JOO W.‐C. , HONG J.‐H. , CHOI S.‐B. , SON H.‐E. , KIM C. H.
Published: May 2016

The synthesized title compound (III) reacts with MeI (IVa) or the methylsilyl chlorides (IVb) and (IVc) to give the 1,1‐disubstituted derivatives (V).
ChemInform Abstract: Fluorosilyl and Fluoroboryl Substituted Cyclotetrasilazanes. Synthesis and Crystal Structures.
Authors: DIPPEL K. , KLINGEBIEL U. , KOTTKE T. , PAUER F. , SHELDRICK G. M. , STALKE D.
Published: May 2016

The monolithium derivative of octamethylcyclotetrasilazane (I) and the dilithiated analogue (V) react with difluorosilanes such as (II) and the difluoroborylamine (VI) with retention of the cyclotetrasilazane structure to yield the mono‐ and disubstituted derivatives of the type (III) ((IIIa) (R2: Me) and (IIIb): space group P21/n, Z=4), (IV) (yields 84‐92%; (IVa) (R2: Me): P21/n, Z=2; (IVa) (R2: tBu): P1, Z=1), and (VII), respectively.
ChemInform Abstract: Studies on Organosilicon Chemistry. Part 100. Pentacoordinate Allylsiliconates in Organic Synthesis: Synthesis of Triethylammonium Bis(catecholato)allylsiliconates and Selective Allylation of Aldehydes.
Authors: HOSOMI A. , KOHRA S. , OGATA K. , YANAGI T. , TOMINAGA Y.
Published: May 2016

The allyl(trimethoxy)silanes (I) react with catechol (II) in the presence of triethylamine (III) to form the siliconates (IV) mentioned in the title.
ChemInform Abstract: Synthesis of the Heptaphosphanortricyclanes R3P7 R, R: Et, iPr, nBu, iBu, SiH2Me, SiH3, Et2P‐SiMe2.
Authors: FRITZ G. , SCHNEIDER H.‐W.
Published: May 2016

The title compounds are synthesized by reaction of Li3P7·3 DME with corresponding alkyl bromides or silyl halides at low temperatures.
ChemInform Abstract: 2,10‐Dichloro‐6‐(aryloxy)dibenzo(d,g)(1,3,6,2)dioxathiaphosphocin 6‐Oxides. Synthesis and Spectral Characteristics.
Authors: REDDY C. D. , ANURADHA K. , BERLIN K. D. , SUNTHANKAR P. S. , MULEKAR S. V.
Published: May 2016

The heterocyclic phosphates (III) mentioned in the title are obtained by base‐induced ring closure of the o,o'‐dihydroxydiphenyl sulfide (I) with the phosphorodichloridates (II).
ChemInform Abstract: Synthesis and Reactions of a Stable 2‐Selenanaphthalene, 1‐Cyano‐2‐methyl‐2‐selenanaphthalene.
Authors: HORI M. , KATAOKA T. , SHIMIZU H. , TSUTSUMI K. , YOSHIMATSU M.
Published: May 2016

The isoselenochromanol (I) is dehydrated to give the isoselenochromene (II) which is chlorinated with sulfuryl chloride and subsequently treated with the silyl cyanide (III) to produce the nitrile (IV).
ChemInform Abstract: iPr2InBr, iPr2InI and iPrInI2.
Authors: HOFFMANN G. G. , FAIST R.
Published: May 2016

The title compounds (IV) and (V) are obtained by reaction of the synthesized triisopropyl‐In (III) with two equiv. InI3 (I) or one equiv. (I) or InBr3, respectively.
ChemInform Abstract: μ‐Hydroxobis(μ‐formato)hexaaquodichromium(III): An Intermediate in the Formation of Basic Chromium Carboxylates.
Authors: TUROWSKI P. N. , BINO A. , LIPPARD S. J.
Published: May 2016

The title cation is obtained by reduction of Cr(VI) oxide (II) in formic acid (I), isolated as its tosylate (IV) (space group C2/c, Z = 8), and characterized by X‐ray structure analysis and magnetic data.
ChemInform Abstract: Phosphinidene and Arsinidene Complexes Containing Pentamethylcyclopentadienyl (Cp*) Ligands at Group 15 Element: Synthesis and Cp* Transfer.
Authors: JUTZI P. , KROOS R.
Published: May 2016

The air‐ and moisture‐sensitive phosphinidene and arsinidene complexes (III) and (IV) (yield 21/23%) are synthesized as shown for the phosphinidene complexes.
ChemInform Abstract: Synthesis, Structure and Reactions of the Novel Cationic Bisbut‐2‐yne Complex (W(CO)(NCMe)(S2CNC4H8)(η2‐MeC2Me)2)(BPh4).
Authors: BAKER P. K. , DREW M. G. B. , FLOWER K. R.
Published: May 2016

The title complex (III) (space group P21/a, Z=4) is obtained by replacement of the iodide ligand in (I) by acetonitrile (II) and characterized by X‐ray structure analysis.
ChemInform Abstract: The Re‐Re Bond in Binuclear Di‐μ‐oxorhenium Complexes Containing the 1,4,7‐Triazacyclononane Ligand.
Authors: BOEHM G. + , WIEGHARDT K. , NUBER B. , WEISS J.
Published: May 2016

Re‐Re double bonds characterize complexes (V) (space group P21/c, Z=2) and (VII) ( P21/n, Z=2).
ChemInform Abstract: Nonacarbonylbis(μ3‐methylidyne)triiron.
Authors: LENTZ D. , MICHAEL H.
Published: May 2016

The parent compound (III) of the bis(alkylidyne)triiron clusters is prepared in a two‐step synthesis by halogen exchange and reduction.
ChemInform Abstract: Synthesis and Characterization of the Linear Trinuclear Complexes (MII 3(O2CCH3)6(biphme)2), M: Mn, Fe.
Authors: RARDIN R. L. , BINO A. , POGANIUCH P. , TOLMAN W. B. , LIU S. , LIPPARD S. J.
Published: May 2016

In the title complexes (III) (for both space group P21/c, Z=2) three two‐valent metal ions form a chain bridged by four bidendate and two monodentate carboxylate ligands.
ChemInform Abstract: The Supercomplex Nature of Buffs ′Ferrocyanethyl′. First Example of a Homoleptic Hydrogen Isocyanide (CNH) Metal Complex.
Authors: RIEGER D. , HAHN F. E. , FEHLHAMMER W. P.
Published: May 2016

Treatment of (I) with hydrogen chloride and ethanol (II) results in the formation of the hydrogen isocyanide iron complex (III).
ChemInform Abstract: Synthesis and Structure of Novel Cu Clusters: Cu30‐xSe15(PiPr3)12 (x = 0, 1) and Cu36Se18(P(tBu)3)12.
Authors: FENSKE D. , KRAUTSCHEID H. , BALTER S.
Published: May 2016

The title clusters (IV) (space group P1, Z=2), (V) (P21/c, Z=4), and (VII) (C2/c, Z=4) are obtained according to the scheme and characterized by X‐ray structure analysis.
ChemInform Abstract: Synthesis and Crystal Structure of Hexanuclear Copper(I) Complexes of μ3‐Pyridine‐2‐thionate.
Authors: KITAGAWA S. , MUNAKATA M. , SHIMONO H. , MATSUYAMA S. , MASUDA H.
Published: May 2016

The structure of the synthesized hexanuclear Cu(I) complex (III) (space group P21/n, Z=2) is confirmed by X‐ray structure analysis.
ChemInform Abstract: Novel Basic Ligands for the Homogeneous Catalytic Carbonylation of Methanol. Part 26. Dynamic and Reactive Behavior of (Ether‐Phosphane)Ruthenium(II) Complexes in Dependence on the O‐Basicity.
Authors: LINDNER E. , KARLE B.
Published: May 2016

The reaction of the ether‐phosphane ligand (II) with (I) results in formation of the bis(chelate) complex (III).
ChemInform Abstract: Synthesis of Metal Free Phthalocyaninetetrakis(N‐cyclopropylsulfonamides).
Authors: YAHYA H. K. , DAWOOD A. A.
Published: May 2016

The phthalocyanine derivative, in which the cyclopropylsulfonylamide groups are attached to the 4,4',4'',4'''‐positions, is prepared analogously to (III) with 63% yield.
ChemInform Abstract: Electrochemical and EPR Studies of Carotenoid Cation Radicals and Dications: Effect of Deuteration.
Authors: KHALED M. , HADJIPETROU A. , KISPERT L.
Published: May 2016

The cyclic voltammograms of the carotenoids (I) in CH2Cl2 indicate a reversible transfer of two electrons.
ChemInform Abstract: Total Synthesis of the Methylfuranosides of 2‐Desoxypentoses and 2,6‐Didesoxyhexoses. Application of 1H and 13C NMR Spectroscopies for the Structure Determination of the Glycosides of 2‐Desoxysugars.
Authors: ARSHAVA B. M. , RAIFEL'D YU. E. , MAKIN S. M.
Published: May 2016

Optimized yields for 17 title compounds, represented in the scheme by (I) and (III), are attained under the conditions A).
ChemInform Abstract: Novel Types of Cyclonucleosides.
Authors: TRONCHET J. M. J. , BENHAMZA R. , BERNARDINELLI G. , GEOFFROY M.
Published: May 2016

The keto cyclonucleoside (Ia) reacts with hydroxylamine (II) to form the oxime (Ib), together with the cyclic hydroxylamine (III), which is solvolyzed to yield (IV).
ChemInform Abstract: Synthesis and Evaluation of Aborted and Extended CC‐1065 Functional Analogues: (+)‐ and (‐)‐CPI‐PDE‐I1, (+)‐ and (‐)‐CPI‐CDPI1, and (.+‐.)‐, (+)‐, and (‐)‐CPI‐CDPI3. Preparation of Key Partial Structures and Definition of an Additional Functional Role of the CC‐1065 Central and Right‐Hand Subunits.
Authors: BOGER D. L. , COLEMAN R. S. , INVERGO B. J. , SAKYA S. M. , ISHIZAKI T. , MUNK S. A. , ZARRINMAYEH H. , KITOS P. A. , THOMPSON S. C.
Published: May 2016

The CC‐1065 analogue (+)‐CPI‐PDE‐I1 (IV) as well as the other, structurally related, title compounds are prepared as shown for (IV).
ChemInform Abstract: The Preparation and Use of Metallo‐6‐vinylidene Penams.
Authors: BUYNAK J. D. , BORATE H. B. , LAMB G. , ISOM H. , HUSTING C. , KHASNIS D.
Published: May 2016

Consecutive treatment of the iodoallene (I) with sec‐butyllithium and acetic acid or the acid chlorides (IV) results in the formation of the acetylene (II) or the keto acetylenes (V).
ChemInform Abstract: Reactions of Pyridines, Pyrimidines and 1,3,5‐Triazines with Nucleophilic Reagents
Authors: ALEKSEEVA N. V. , YAKHONTOV L. N.
Published: May 2016

Review: (169 refs.
ChemInform Abstract: Structure of Disodium Triaquatri‐μ‐sulfato‐thorate(IV) Trihydrate.
Authors: HABASH J. , SMITH A. J.
Published: May 2016

Prismatic crystals of Na2(Th(SO4)3(H2O)3)·3 H2O are obtained by slow evaporation of a solution of Th(SO4)2·9 H2O and Na2SO4 at room temperature.
ChemInform Abstract: Structure of a Triarsenate: Na3H2As3O10.
Authors: DRISS A. , JOUINI T.
Published: May 2016

Crystals of the title compound are prepared by hydrothermal treatment of NaH2AsO4·H2O (533 K, 24 h, autoclave).
ChemInform Abstract: CaCuP2O7: A Structure Closely Related to α‐Ca2P2O7.
Authors: RIOU D. , GOREAUD M.
Published: May 2016

The title compound is prepared by reaction of CaCO3, CuO, and (NH4)2HPO4 (1.
ChemInform Abstract: Influence of High Concentrations of Fluoride on the Electrosynthesis of Peroxodisulfates at β‐PbO2 Anodes.
Authors: SCHELER I. , WABNER D. W.
Published: May 2016

As already observed by other authors, addition of high amounts of F‐ increases the current efficiency of S2O82‐ during electrolysis in H2SO4/(NH4)2SO4 solutions at β‐PbO2 anodes.
ChemInform Abstract: The Effect of Phosphoric Acid on Rust Studied by Moessbauer Spectroscopy.
Authors: NIGAM A. N. , TRIPATHI R. P. , DHOOT K.
Published: May 2016

The influence of H3PO4 on the corrosion products of mild steel samples corroded in different media (brackish water, and aqueous solutions of NaCl, LiCl, NH4NO3) is studied systematically.
ChemInform Abstract: The Kinetics of Aluminum‐7075 Corrosion by Uranium Hexafluoride
Authors: SANIGER J. M. , ALBA F. , GARRIDO S. J. , AVENDANO E.
Published: May 2016

are studied in the temp. range 20‐200 °C. A protective film grows in the temp. range 20‐140 °C. At these temp., the growth of the corrosion film is controlled by the transport of ions through the pores of the film.
ChemInform Abstract: The Synthesis of Bromocyclophosphazenes.
Authors: SEGER J. , KOURIL M. , ALBERTI M. , PRONAYOVA N.
Published: May 2016

The new method developed for the synthesis of cyclic phosphazenes avoids the use of toxic solvents and reduces the reaction time.
ChemInform Abstract: Conformation of (Z)‐3‐Carboxymethyl‐((2E)‐2‐methyl‐3‐phenylpropenylidene)rhodanine (Epalrestat) (I), a Potent Aldose Reductase Inhibitor: X‐Ray Crystallographic, Energy Calculational, and NMR Studies.
Authors: ISHIDA T. , IN Y. , INOUE M. , TANAKA C. , HAMANAKA N.
Published: May 2016

In order to study the key atoms and their spatial disposition necessary for high aldose reductase inhibitory activity, the space group for the title compound (I) (P1, Z=2) is determined.
ChemInform Abstract: Aluminirene (HAlC2H2) and Aluminirane (HAlC2H4): Aluminum‐Substituted Counterparts of Cyclopropene and Cyclopropane.
Authors: XIE Y. , SCHAEFER H. F. III
Published: May 2016

Theoretical molecular structures, energetics and vibrational frequencies of all isomers of hydrogenated aluminum‐acetylene and hydrogenated aluminum‐ethylene systems are predicted by ab initio quantum mechanical methods.
ChemInform Abstract: Amino Acid Esters as Chiral Auxiliaries in Lewis Acid Catalyzed Diels‐Alder Reactions.
Authors: WALDMANN H.
Published: May 2016

The asym. Diels‐Alder reaction between various dienes such as (I) and unsaturated N‐acyl‐(S)‐proline esters such as (II) or (V) is investigated.
ChemInform Abstract: Thermal Diels‐Alder Reactions with N‐(2‐Alkenoyl)‐(S)‐proline Esters as Chiral Dienophiles Using Organic and Aqueous Reaction Media.
Authors: WALDMANN H. , DRAEGER M. +
Published: May 2016

The asym. Diels‐Alder reaction of cyclopentadiene with N‐acryloyl‐(S)‐proline benzyl ester or N,N'‐fumaroyl‐bis(proline ester) (see preceding abstract) which is reported to proceed with high stereoselection in the presence of a Lewis catalyst, can also be carried out without a catalyst using an aqueous solvent.
ChemInform Abstract: Extremely High Rate Accelerations in Aldol Reactions of α‐Alkoxy Ketones: Reactivity Governed by Substituent Field Effects.
Authors: DAS G. , THORNTON E. R.
Published: May 2016

Very large accelerations are discovered in aldol reactions of α‐substituted ketones, e.g. (I), with the Li enolate (III) of pinacolone (relative reactivities are tabulated).
ChemInform Abstract: Novel Silicon‐Directed Alkylative Cyclization.
Authors: TROST B. M. , URABE H.
Published: May 2016

Only cyclization products are obtained by treatment of the allenes (I) or (VI) with EtAlCl2 and Me2AlCl or Me3Al, respectively.
ChemInform Abstract: Linearly Fused vs Bridged Regioselection in the Intramolecular 1,3‐Diyl Trapping Reaction.
Authors: MASJEDIZADEH M. R. , DANNECKER‐DOERIG I. , LITTLE R. D.
Published: May 2016

The isobutenol (I) is coupled with the 1‐bromo‐3‐siloxypropane (II) to produce the hexanediol derivative (III).
ChemInform Abstract: Kinetics of Reactions Between Methyl and Acetyl Radicals in Gas Phase Produced by Flash Photolysis of Acetic Anhydride.
Authors: HASSINEN E. , KALLIORINNE K. , KOSKIKALLIO J.
Published: May 2016

The flash photolysis of (I) leads to 52% photodissociation and to 48% intramolecular hydrogen transfer to give (IV)‐(VIII).
ChemInform Abstract: Monocyclic Enediyne Collapse to 1,4‐Diyl Biradicals: A Pathway Under Strain Control.
Authors: SNYDER J. P.
Published: May 2016

Some hypothetical compounds of type (I) are studied by theoretical calculations including also 10‐membered enediynes.
ChemInform Abstract: Copper(I)‐ and Copper(II)‐Mediated Two‐Electron Oxidations of Benzylic Alcohols and Diarylacetic Acids by Trimethylamine N‐Oxide.
Authors: CAPDEVIELLE P. , SPARFEL D. , BARANNE‐LAFONT J. , CUONG N. K. , MAUMY M.
Published: May 2016

The copper(I) alkoxides, prepared by reaction of the sodium alkoxides (I) or (III) with copper(I) chloride, are oxidized with excess trimethylamine N‐oxide, producing the ketones (II) or the salicylaldehydes (IV).
ChemInform Abstract: Mechanism of Photoreduction of Diethyl Benzylidene Malonates by NAD(P)H Model and Comparison with Thermal Reaction.
Authors: DENG G. , XU H.‐J. , CHEN D.‐W.
Published: May 2016

In a deuterated solvent the photoreduction of title compounds such as (I) leads to β‐deuterated main products (cf.
ChemInform Abstract: The Reduction of Nitrile with 2‐Propanol Over Hydrous Zirconium Oxide.
Authors: TAKAHASHI K. , SHIBAGAKI M. , MATSUSHITA H.
Published: May 2016

Using hydrous zirconium oxide as the catalyst, vapor‐phase reduction of nitriles with 2‐propanol proceeds to give the corresponding alcohols as the main products.
ChemInform Abstract: Regioselectivity of the Amination of Some Nitroisoquinolines by Liquid Ammonia/Potassium Permanganate.
Authors: WOZNIAK M. , BARANSKI A. , NOWAK K. , PORADOWSKA H.
Published: May 2016

Amination of the 5‐nitroisoquinolines (I) by liquid NH3 (II) in the presence of KMnO4 proceeds with high regioselectivity to afford the 6‐amino derivatives (III).
ChemInform Abstract: An Improved Method for Reductive Alkylation of Amines Using Titanium(IV) Isopropoxide and Sodium Cyanoborohydride.
Authors: MATTSON R. J. , PHAM K. M. , LEUCK D. J. , COWEN K. A.
Published: May 2016

Amines such as (I) are coupled with cyclic ketones such as (II) in the presence of titanium isopropoxide.
ChemInform Abstract: Enzyme‐Catalyzed Interesterification Procedure for the Preparation of Esters of a Chiral Secondary Alcohol in High Enantiomeric Purity.
Authors: MACFARLANE E. L. A. , ROBERTS S. M. , TURNER N. J.
Published: May 2016

Enzyme‐catalyzed hydrolysis of the racemic acetoxybicyclo(3.2.0)heptene (±)‐(I) yields the (6R)‐alcohol (+)‐(II) with moderate enantiomeric excess.
ChemInform Abstract: Nucleophilic Attack at Heterocyclic Nitrogen: Unusual Reactivity of the Benzotriazole Heterocyclic Ring.
Authors: KATRITZKY A. R. , RACHWAL S. , OFFERMAN R. J. , NAJZAREK Z. , YAGOUB A. K. , ZHANG Y.
Published: May 2016

Grignard reagents attack 1‐imidoylbenzotriazoles (III) at the imidoyl carbon atom and also at the benzotriazolyl N‐2 and N‐3 atoms leading to complex reaction mixtures, the composition of which allows identification of the main reaction paths.
ChemInform Abstract: Claisen Orthoester Rearrangement Reaction with Secondary and Tertiary Allylic Alcohols: Synthesis of 1,2‐Secochrysanthemates and Their Structural Analogues.
Authors: KELKAR S. V. , ARBALE A. A. , JOSHI G. S. , KULKARNI G. H.
Published: May 2016

Mesityl oxide (I) and citral (IV) are converted to the allylic alcohols (IIa) ‐ (IIc) which are consecutively heated with triethyl orthoacetate (V) and phosphoric acid, performing the rearrangement mentioned in the title to give the γ,δ‐unsaturated carboxylates (VI).
ChemInform Abstract: Bromo(3)cumulene and Bromo Enyne Radical Cyclization to Cyclopentenyne Products.
Authors: ZIEGLER C. B. JUN.
Published: May 2016

Wittig reaction of the phosphonium bromide (II) with the ketones (I) gives the cumulenes (III) via elimination of HBr.
ChemInform Abstract: An Unusual Chemoselectivity in Cobalt(II) Chloride‐Catalyzed Cleavage of Oxiranes with Anilines: A Highly Regioselective Synthesis of β‐Amino Alcohols.
Authors: IQBAL J. , PANDEY A.
Published: May 2016

The oxiranes (I) are cleaved with the amines (II) in the presence of cobalt dichloride to form the vicinal amino alcohols (III).
ChemInform Abstract: Sulfinic Acids and Related Compounds. Part 24. Monothioquinone S,S‐Dioxides and Their Relation to Convergent Syntheses Involving Hydroxyarenesulfonyl Chlorides.
Authors: FIELD L. , LEE C.
Published: May 2016

The hydroxybenzenesulfonyl chlorides (I) react with the p‐methylthiophenol to form the sulfinic acids (II).
ChemInform Abstract: A General Method for the Reductive Carbamation and Sulfonamidation of Aldehydes.
Authors: ALEXANDER M. D. , ANDERSON R. E. , SISKO J. , WEINREB S. M.
Published: May 2016

Seven aldehydes such as (I) are treated with the N‐sulfinyl sulfonamide (II) in the presence of triethylsilane and boron trifluoride etherate to produce the sulfonamidation products (III).
ChemInform Abstract: Synthesis, Fungicidal, and Antimicrobic Properties of 1‐Thiocyanato‐1‐alkoxycarbonyl‐2‐arylethanes.
Authors: GRISHCHUK B. D. , PRODANCHUK N. G. , GORBOVOI P. M. , NIVALOV V. N. , SINCHENKO V. G.
Published: May 2016

Reaction of the arenediazonium salts (I) with the acrylic esters (II) and potassium thiocyanate (III) in the presence of copper(II) acetate gives the phenylthiocyanatopropionic(isobutyric) acid esters (IV).
ChemInform Abstract: Stable Simple Enols. Part 25. Unusual Kinetic Stability of Enols to Ketonization: 1,2‐Dimesityl‐3‐methylbut‐1‐en‐1‐ol and Related β‐Alkyl‐α,β‐dimesitylethenols.
Authors: NADLER E. B. , RAPPOPORT Z.
Published: May 2016

Addition of the dimethylcuprate (II) to the enones (I) gives regioselectively the dimesitylbutenols (III) mentioned in the title.
ChemInform Abstract: Thermal Isomerizations of Allenyl Cycloalken‐3‐yl Ethers.
Authors: DULCERE J.‐P. , CRANDALL J. K.
Published: May 2016

Heating of the allenyl cyclopentenyl ether (I) results in isomerization to give the cyclopentenylacrolein (II).
ChemInform Abstract: Synthesis of 1,2‐Benzisothiazoles by the Oxidative Ring Contraction of 2‐Aryl‐ and 4‐Aryl‐3,4‐dihydro‐2H‐1,3‐benzothiazines.
Authors: SZABO J. , SZUECS E. + , FODOR L. , BERNATH G. , SOHAR P.
Published: May 2016

Sodium periodate oxidation of the benzothiazine (I) forms the benzisothiazole (II), whereas oxidation of the N‐substituted benzothiazines (III) yields the benzisothiazolidine oxides (IV).
ChemInform Abstract: Nickel(0)‐Catalyzed Cycloaddition of Silyl Diynes with Carbon Dioxide to Silyl Bicyclic α‐Pyrones.
Authors: TSUDA T. , MORIKAWA S. , HASEGAWA N. , SAEGUSA T.
Published: May 2016

Nickel‐catalyzed coupling of silyl diynes such as (I) with carbon dioxide (II) produces the bicyclic α‐pyrones (III).
ChemInform Abstract: Synthesis of Some 3,4‐Dihydro‐2H‐1‐benzothiopyran‐4‐ols.
Authors: PRUITT V. L. , BERLIN K. D. , HIRSCH K. S.
Published: May 2016

The phenylacetate (I) is converted to the aryl sulfide (VII).
ChemInform Abstract: Synthesis of 1‐(Aminooxy)‐4‐((3‐nitro‐2‐pyridyl)dithio)butane and 1‐(Aminooxy)‐4‐((3‐nitro‐2‐pyridyl)dithio)but‐2‐ene, Novel Heterobifunctional Cross‐Linking Reagents.
Authors: WEBB R. R. II , KANEKO T.
Published: May 2016

Reaction of the acethydroximate (I) with the dibromides (II) gives the O‐alkylation products (III).
ChemInform Abstract: α‐Lithioamine Synthetic Equivalents: Syntheses of Diastereoisomers from the Boc Piperidines.
Authors: BEAK P. , LEE W. K.
Published: May 2016

Boc‐protected piperidines such as (I) are α‐lithiated and subsequently coupled with aldehydes such as (II) to produce the corresponding erythro‐alcohols (III), together with the cyclized form (IV) of the threo‐alcohols.
ChemInform Abstract: Tricyclic Pyridine Derivatives with High Affinity to the Central Benzodiazepine Receptor.
Authors: FISCHER U. , MOEHLER H. + , SCHNEIDER F. , WIDMER U.
Published: May 2016

Novel tricyclic heterocycles such as (V)‐(IX) are prepared on different routes as shown for (V) and (VI) and evaluated for their affinity to the central benzodiazepine receptor.
ChemInform Abstract: Reaction of 2‐Chlorocyclohepta(b)pyrrole‐3‐carbaldehyde with o‐Phenylenediamine.
Authors: ABE N. , EMOTO Y.
Published: May 2016

Reaction of the aldehyde (I) with o‐phenylenediamine (II) gives the products (III) and (IV) instead of the expected benzodiazepine (V).
ChemInform Abstract: Reaction of the Lithium Derivative of Diethyl Phenylmethanephosphonate (I) with Ketones.
Authors: PETROVA J. , VASSILEV N. G. , KIRILOV M.
Published: May 2016

The yields of the adducts (III), (V), (VII) and (VIII) are higher at short reaction times (1‐15 min).
ChemInform Abstract: Acceleration of the Phosphorylation of Phenylacetylene with Red Phosphorus by Ultrasound.
Authors: TROFIMOV B. A. , GUSAROVA N. K. , MALYSHEVA S. F. , RAKHMATULINA T. N. , POLUBENTSEV A. V. , VORONKOV M. G.
Published: May 2016

The title reaction, leading to the formation of the phosphine (III), is accelerated by the application of ultrasound.
ChemInform Abstract: A Novel Preparation of Spirophosphoranes with an Aminomethyl Group at the Phosphorus.
Authors: TERENT'EVA S. A. , PUDOVIK M. A. , PUDOVIK A. N.
Published: May 2016

The benzoxazaphospholane (I) reacts with the glycols (II) under alcoholysis and N→P migration to give the spirophosphoranes (III).
ChemInform Abstract: Reactions of μ3‐Bridging Alkyne Ligands on Heterometallic Clusters.
Authors: BANTEL H. , POWELL A. K. , VAHRENKAMP H.
Published: May 2016

The preparation of the alkyne‐bridged heterometallic clusters (IV) and (V) (yields 59/45/21%) occurs by the one‐pot reaction starting with the RuCo2 cluster (I) as demonstrated for the examples (IV).
ChemInform Abstract: The First Second‐Row Triketone Complex Structure: Synthesis and Properties of a Substituted (1,3,5‐Pentanetrionato)(μ‐oxo)bis(dioxomolybdenum(VI)).
Authors: BORER L. L. , SINN E.
Published: May 2016

The title complex is obtained as its DMSO diadduct (IV) (space group P21/n, Z=4) as shown and characterized by X‐ray structure analysis, magnetic and spectroscopic measurements as well as by cyclic voltammograms.
ChemInform Abstract: Selective Binding and Activation of One Aldehyde Enantioface by a Chiral Transition‐Metal Lewis Acid: Synthesis, Structure, and Reactivity of Rhenium Aldehyde Complexes ((η5‐C5H5)Re(NO)(PPh3)(η2‐O=CHR))+X‐.
Authors: GARNER C. M. , QUIROS MENDEZ N. , KOWALCZYK J. J. , FERNANDEZ J. M. , EMERSON K. , LARSEN R. D. , GLADYSZ J. A.
Published: May 2016

The reaction of the dichloromethane complex (III) with aldehydes such as (IV) gives the π‐aldehyde complexes (V) (6 examples), in which one R‐CHO enantioface is bound with high specificity.
ChemInform Abstract: Chemistry of Boron. Part 204. An Unusual (2 + 2)‐Cycloaddition Reaction of Dicobalt Octacarbonyl.
Authors: CHANNAREDDY S. , LINTI G. , NOETH H. +
Published: May 2016

The (2 + 2)cycloaddition of (II) with (I) is an example of a metal‐mediated activation of CO.
ChemInform Abstract: Synthesis of Novel Polyfunctional Nickel(II)‐Nickel(II) Dimer Ni2Cl2(C(SiMe3)(PMe3))2 by Photolysis of the First ((Trimethylsilyl)diazomethyl)nickel(II) Complex Ni(C(N2)SiMe3)Cl(PMe3)2.
Authors: KOENIG H. + , MENU M. J. , DARTIGUENAVE M. , DARTIGUENAVE Y. , KLEIN H. F.
Published: May 2016

As the first example of a C‐bonded 3d metal diazoalkane complex the Ni(II) compound (III) is synthesized as shown.
ChemInform Abstract: Direct Electrochemical Synthesis of Copper and Silver Derivatives of Alkanedithiols and Crystal Structure of (Cu2S2C3H6‐1,2·(C6H5)2PCH2P(C6H5)2)4·4 CH3CN.
Authors: ANNAN T. A. , KUMAR R. , TUCK D. G.
Published: May 2016

The electrochemical oxidation of Cu or Ag in solutions of various sym. or asym.
ChemInform Abstract: Fixation of Ureas and Thioureas on Trinuclear Ruthenium Clusters: Synthesis and Molecular Structure of (μ2‐H)Ru3(CO)9(μ3‐NPhCSNHPh).
Authors: BODENSIECK U. , STOECKLI‐EVANS H. , SUESS‐FINK G. +
Published: May 2016

The trinuclear clusters (III) are synthesized as demonstrated for the thiourea derivatives (IIIa) (space group P21/m, Z=2) and (IIIb).
ChemInform Abstract: Trapping of Tricyclo(3.3.1.03,7)non‐3(7)‐ene with (Ph3P)2Pt. Structure of the (Ph3P)2Pt Complex of a Highly Pyramidalized Alkene.
Authors: KUMAR A. , LICHTENHAN J. D. , CRITCHLOW S. C. , EICHINGER B. E. , BORDEN W. T.
Published: May 2016

NMR coupling constants indicate a highly pyramidalized geometry at the olefinic carbons.
ChemInform Abstract: Technical Procedures for the Syntheses of Carotenoids and Related Compounds from 6‐Oxo‐isophorone: Syntheses of (3R,3′R)‐Zeaxanthin. Part 2.
Authors: SOUKUP M. , WIDMER E. , LUKAC T.
Published: May 2016

A 72% overall yield of the synthon (IX), required for the synthesis of the title compound (XI), can be achieved using the new reaction sequence shown in the scheme.
ChemInform Abstract: Synthesis of (3S,4R,3′S,4′R)‐ and (3S,4S,3′S,4′S)‐Crustaxanthins and Further Compounds with 3,4‐Dihydroxy β‐End‐groups.
Authors: BUSCHOR D. J. , EUGSTER C. H.
Published: May 2016

The enantiomerically pure title compounds (IV) and (V) are both synthesized starting from the aldehyde (I).
ChemInform Abstract: The Synthesis of the Labdane Diterpenoid Erigerol and of Analogous Compounds.
Authors: KIENZLE F. , STADLWIESER J. , RANK W. , SCHOENHOLZER P. +
Published: May 2016

The synthesis of the title compound (I) and of some analogues is described in a 23‐step sequence starting from (I).
ChemInform Abstract: Solid‐Phase‐Mediated Peptide Heterodisulfide Formation.
Authors: PONSATI B. , RUIZ‐GAYO M. , GIRALT E. , ALBERICIO F. , ANDREU D.
Published: May 2016

A useful new strategy of general applicability is presented for heterodisulfide formation which uses stepwise displacements in a preformed disulfide driven by different acidities according to Pep1‐SH + Y‐S‐S‐X‐Pol → Pep1‐S‐S‐X‐Pol + Y‐SH; Pep1‐S‐S‐X‐Pol + HS‐Pep2 → Pep1‐S‐S‐Pep2 + HS‐X‐Pol.
ChemInform Abstract: A Simple Approach to New 5‐Butenylideneimidazolin‐2‐ones from 2‐Amino‐2‐deoxy‐D‐glucose.
Authors: KOVACS J. , PINTER I. , MESSMER A. , TOTH G. , LENDERING U. , KOELL P. +
Published: May 2016

Treatment of the 2‐deoxy‐2‐amino‐D‐glucose hydrochloride (I) with potassium cyanate (II) results in the formation of a complex mixture from which the acyclic (IV) and cyclic derivative (V) are isolated after acetylation.
ChemInform Abstract: Synthesis of Sugar N‐(2‐Thiazolin‐2‐yl)thioureas.
Authors: AVALOS M. , BABIANO R. , CINTAS P. , JIMENEZ J. L. , PALACIOS J. C.
Published: May 2016

The reaction of 2‐deoxy‐2‐isothiocyanato sugars such as (I) with 2‐chloroethylamine hydrochloride (II) in pyridine yields thiazolinylthioureas such as (III).
ChemInform Abstract: Stereoselective Synthesis of 2‐Azapurine 2′‐Deoxy‐β‐D‐ribonucleosides by Nucleobase‐Anion Glycosylation.
Authors: KAZIMIERCZUK Z. , SEELA F.
Published: May 2016

Nucleobase‐anion glycosylation of the azapurine (II) with the pentafuranosyl chloride (I) yields the regioisomeric products (IIIa), (IV) and (V) stereoselectively.
ChemInform Abstract: Asymmetric Synthesis of (‐)‐Dehydroclausenamide.
Authors: HUANG D.‐F. , HUANG L.
Published: May 2016

The title compound (X), a constituent of Clausena lansium with potent hepatoprotective activity, is prepared starting from cinnamyl alcohol (I) in 2.4% overall yield with > 95% e.e.
ChemInform Abstract: Ab initio Study on Digallane(4), Ga2H4.
Authors: LAMMERTSMA K. , LESZCZYNSKI J.
Published: May 2016

Ab initio MO calculations of the potential energy surface of the still unknown digallane predict the saltlike tridentate structure (I) to be the most stable isomer of the digallanes (I)‐(VIII).
ChemInform Abstract: Crystal Growth of Tungsten Carbide Plates by Condensation of High‐Temperature Ultrasupersaturated Gas.
Authors: YAMADA K.
Published: May 2016

A high temp. ultrasupersaturated gas derived from WC powder by means of the cylindrical shock wave method is used to prepare fine WC plates of various growth forms (trigonal, hexagonal, pentagonal, trapezoidal, rhombic).
ChemInform Abstract: Electrochemical Investigations on Excimer‐Laser Deposited Y‐Ba‐Cu‐O High‐Temperature‐Superconductor Thin Film Electrodes.
Authors: SRIVASTAVA S. K. , ROAS B. , JUETTNER K. +
Published: May 2016

Epitaxial YBa2Cu3O7δ thin film electrodes, deposited by the excimer‐laser technique on (100)SrTiO4, exhibit quite a different and unique electrochemical behavior in MeCN solution as compared to that of polycrystalline sintered Y‐Ba‐Cu‐O or Pt electrodes.
ChemInform Abstract: An Investigation of Hydrogen Evolution on Raney‐Nickel Composite‐Coated Electrodes
Authors: CHOQUETTE Y. , BROSSARD L. , LASIA A. , MENARD H.
Published: May 2016

in 30 wt.% NaOH aqueous solution at 70 °C by means of the ac impedance technique is undertaken to determine the detailed kinetics of the reaction and the surface coverage of the electrochemically activated electrodes by adsorbed hydrogen.
ChemInform Abstract: Some Unique Aspects of Electrochemical Processes at the Group Ib Metal/Aqueous Solution Interface.
Authors: BURKE L. D. , LEE B. H. , RYAN T. G.
Published: May 2016

A unique feature of the Cu, Ag, and Au electrode systems is that they exhibit an adatom (M*)/hydrous oxide transition in which the cation is in the univalent state (M+).
ChemInform Abstract: Application of Ion Implantation/RBS to the Study of Electrocatalysis. Comparison of Chlorine Evolution at Ir‐Implanted and Ru‐Implanted Titanium Electrodes.
Authors: KELLY E. J. , VALLET C. E. , WHITE C. W.
Published: May 2016

Ir‐implanted titanium near‐surface alloys are prepared by ion implantation, characterized by Rutherford backscattering (RBS), and subsequently anodically oxidized to form electrocatalytically active IrxTi1‐xO2/Ti (I) electrodes.
ChemInform Abstract: Kinetics of Titanium(IV) Chloride Oxidation
Authors: PRATSINIS S. E. , BAI H. , BISWAS P. , FRENKLACH M. , MASTRANGELO S. V. R.
Published: May 2016

by Ar/O2 mixtures is studied in a furnace aerosol reactor at temp. in the range 700‐1000 °C. The oxidation rate is first order with respect to (TiCl4) and nearly zero order for (O2) up to a 10‐fold excess.
ChemInform Abstract: Preparation of the Zeolite Nu‐15.
Authors: DUBANSKA V.
Published: May 2016

A novel vanadium zeolite of a composition corresponding to formula (I) is synthesized by hydrothermal decomposition of a vanadium glass (15‐17% Na2O, 15‐17% Al2O3, 25‐40% SiO2, 30‐45% V2O5) at 120‐160 °C in strongly basic solution in NaOH.
ChemInform Abstract: The 4‐Chloro‐2‐oxo‐1,3,5,5,8‐pentamethyl‐1,3,8‐triaza‐5‐azonia‐4λ5‐phosphasp# iro(3.4)octyl Cation: X‐Ray Crystal Structure Determination and Variable Temperature 1H NMR Spectra.
Authors: KAUKORAT T. , ERNST L. , SCHMUTZLER R. , SCHOMBURG D.
Published: May 2016

The 1H NMR spectrum of the spirophosphorane (Ia) at room temp. indicates dynamic behavior of the cation involving exchange of N‐methyl groups.
ChemInform Abstract: The Cyclodimerization of Aryl Vinyl Sulfones: A Facile and Specific Reaction when Activated by Cathodic Electron Transfer.
Authors: DELAUNAY J. , MABON G. , ORLIAC A. , SIMONET J.
Published: May 2016

The aryl vinyl sulfones (I) are dimerized by very low cathodic currents to give the trans‐substituted cyclobutanes (II).
ChemInform Abstract: The Nucleophilic Displacement Route to Homochiral Arylphosphine Oxides.
Authors: BROWN J. M. , CAREY J. V. , RUSSELL M. J. H.
Published: May 2016

The results show that it is possible to prepare homochiral di‐ and triarylphosphine oxides (X) by two sequential nucleophilic displacements on a derivative (III) (used without purification) of PPhCl2 (II) utilizing (‐)‐ephedrine as a chiral auxiliary.
ChemInform Abstract: Directed Nitrile Oxide Cycloaddition Reactions. The Use of Hydrogen Bonding to Direct Regio‐ and Stereochemistry in Nitrile Oxide Cycloadditions with Cyclopentenylamides.
Authors: CURRAN D. P. , CHOI S.‐M. , GOTHE S. A. , LIN F.‐T.
Published: May 2016

The 1,3‐dipolar cycloaddition reaction of the 3‐substituted cyclopentenes (I) with benzonitrile oxide (II) generated in situ yields the two regioisomeric cyclization products (III) and (IV).
ChemInform Abstract: On the Oxidation of Saturated Hydrocarbons with H2O2 in the Presence of Iron(II) Picolinate or Iron(II) 1,10‐Phenanthroline‐2‐carboxylate.
Authors: BALAVOINE G. , BARTON D. H. R. , BOIVIN J. , GREF A.
Published: May 2016

Cyclohexane (I) is oxidized with 30% H2O2 in the presence of pyridine, acetic acid, and an iron‐containing complex catalyst as shown in the reaction scheme to give mainly cyclohexanone and a small amount of cyclohexanol.
ChemInform Abstract: Highly Selective Heterogeneous Palladium‐Catalyzed Hydrogenations Using Triethoxysilane and Water.
Authors: TOUR J. M. , COOPER J. P. , PENDALWAR S. L.
Published: May 2016

Treatment of the alkenes (I) or the alkynes (III) and (IV) with triethoxysilane in the presence of Pd(II) and water results in the formation of the corresponding hydrocarbons (II) and (V) respectively.
ChemInform Abstract: Enantioselective Synthesis of Tertiary α‐Hydroxy Carbonyl Compounds Using ((8,8‐Dichlorocamphoryl)sulfonyl)oxaziridine.
Authors: DAVIS F. A. , WEISMILLER M. C.
Published: May 2016

The asymmetric oxidation of the enolates derived from cyclic ketones such as (I) with the asymmetric oxaziridine (II) yields the corresponding α‐hydroxy derivatives, e.g. (R)‐(III) with high enantiomeric excess.
ChemInform Abstract: Synthesis of 20‐Iodoeicosanoic and 20‐(125I)‐Iodoeicosanoic Acids.
Authors: PROTIVA J. , PECKA J. , URBAN J. , ZIMA J.
Published: May 2016

The synthesis of the title compounds (VIb) and (VIc) uses the readily available synthons (II) and (III) as building blocks.
ChemInform Abstract: Stereoselective Generation and Aldol Reaction of Tetrafluoropropanamide Boron Enolates Leading to threo‐2‐Fluoro‐2‐trifluoromethyl‐3‐hydroxy Alkanamides.
Authors: ISHIHARA T. , KUROBOSHI M. , YAMAGUCHI K.
Published: May 2016

Treatment of the amide (III) with the dialkylboryl triflate (IV) and ethyldiisopropylamine yields the boryl enolates (V) which react with aldehydes such as (VI) to give predominantly threo‐2‐fluoro‐2‐trifluoromethyl‐3‐hydroxyalkanamides, e.g. (VII).
ChemInform Abstract: A Regio‐ and Stereoselective Route to 1,1,3‐ and 1,2,3‐Trihalogenobutadienes by Dehydrohalogenation of Alkyl‐Substituted 1,1,2,3‐Tetrahalogenocyclopropanes.
Authors: BAIRD M. S. , MAHLI B. S. , SHEPPARD L.
Published: May 2016

Non‐terminal dihalogenoalkenes, e.g. (I), react with dichloro‐ or dibromocarbene, generated in situ, to form tetrahalogenocyclopropanes of definite stereochemistry (e.g.
ChemInform Abstract: A Convenient Large‐Scale Synthesis of Cyclobutyl Halides.
Authors: DUPONT A. C. , AUDIA V. H. , WAID P. P. , CARTER J. P.
Published: May 2016

Cyclobutyl chloride (II) is prepared by treatment of cyclobutanecarboxylic acid (I) with lead tetraacetate and lithium chloride.
ChemInform Abstract: The Synthesis of Chiral Cycloheptane Precursors of Guaiane Sesquiterpenes.
Authors: BROCKSOM T. J. , PESQUERO E. T. C. , LOPES F. T.
Published: May 2016

The menthene (I) and α‐terpineol (VIII) are subjected to cyclopropanation with dibromocarbene, followed by silver‐promoted debrominative ring expansion, to give the cycloheptenols (IV) and (V) or (X) and (XI), together with the cyclic ether (XII).
ChemInform Abstract: HBr Cleavage of Cubane‐1,4‐dicarboxylic Acid. Easy Entry into the Nortwistbrendane(ene) System.
Authors: EATON P. E. , MILLIKAN R. , ENGEL P.
Published: May 2016

Treatment of the cubanedicarboxylic acid (I) with HBr for a short time forms the bromodicarboxylic acid (II) which is converted into the corresponding diester (IV) and the lactone (VI).
ChemInform Abstract: Silafunctional Compounds in Organic Synthesis. Part 46. Platinum‐Catalyzed Intramolecular Hydrosilation of Allylamines: Formation of 1‐Aza‐2‐silacyclobutanes and Application to Stereoselective Synthesis of 2‐Amino Alcohols.
Authors: TAMAO K. , NAKAGAWA Y. , ITO Y.
Published: May 2016

The N,N‐bis(dimethylsilyl)allylamines (I) undergo a Pt‐catalyzed intramolecular hydrosilation reaction to form the 1‐aza‐2‐silacyclobutanes (II) and (III) with a high selectivity for the trans‐configurated isomer (II).
ChemInform Abstract: Deamination and Thiolation of Mannich Bases Derived from Conjugated Styryl Ketones.
Authors: DIMMOCK J. R. , JONNALAGADDA S. S. , REID R. S. , ARTECA G. A. , MEZEY P. G.
Published: May 2016

Mannich bases such as (I) and bis‐Mannich bases such as (III) form the pentadienones (II) upon hydrolysis at 37°C/pH 7.4.
ChemInform Abstract: Synthesis and Acid‐Base Properties of Hydrated Hexasulfonic Calix(6)arene Acid
Authors: SCHARFF J.‐P. , MAHJOUBI M. , PERRIN R.
Published: May 2016

(I).
ChemInform Abstract: Intramolecular Cyclization of 9,10‐Anthraquinones Promoted by Reaction with Halogenophosphoranes.
Authors: KUTYREV A. A. , BIRYUKOV V. V. , LITVINOV I. A. , KATAYEVA O. N. , MUSIN R. Z. , ENIKEYEV K. M. , NAUMOV V. A. , ILYASOV A. V. , MOSKVA V. V.
Published: May 2016

A previously unknown reaction of halogenophosphorus compounds (II), (VI) with peri‐hydroxy(amino)‐9,10‐anthraquinones, e.g. (I), (IV), (VIII), (X) leads to products such as (V), (VII), (IX), (XI).
ChemInform Abstract: New Syntheses of Cyclopenta(cd)pyrene 3,4‐Oxide and 4‐Pyrenylacetic Acid.
Authors: SAHALI Y. , SKIPPER P. L. , TANNENBAUM S. R.
Published: May 2016

Lithiation of the bromopyrene (I) followed by coupling with ethylene oxide (II) gives the hydroxyethylpyrene (III) which is oxidized with NCS and subsequently with silver oxide to produce the pyrenylacetic acid (IV).
ChemInform Abstract: Preparation of (S)‐4‐Methyloxetan‐2‐one (β‐Butyrolactone) by Lactonization of (R)‐3‐Hydroxybutyric Acid with Triethyl Orthoacetate.
Authors: BREITSCHUH R. , SEEBACH D.
Published: May 2016

Coupling of the 3‐hydroxybutanoate (I) with the orthoacetate (II) yields the dioxanone (6R)‐(III).
ChemInform Abstract: Asymmetric Synthesis of 2,4‐Disubstituted Butyrolactones Using the Iron Chiral Auxiliary ((η5‐C5H5)Fe(CO)(PPh3)).
Authors: DAVIES S. G. , POLYWKA R. , WARNER P.
Published: May 2016

Treatment of the lithium enolate (I), derived from the corresponding homochiral (S)‐propanoyl complex, with the homochiral (R)‐oxide (II) gives (III) with retention of configuration at both the homochiral precursors and with formation of the new α‐chiral center completely stereoselective according to 1H NMR analysis.
ChemInform Abstract: Potentially Mutagenic, Chlorine‐Substituted 2(5H)‐Furanones: Studies of Their Synthesis and NMR Properties.
Authors: LALONDE R. T. , PERAKYLA H. , HAYES M. P.
Published: May 2016

PCC oxidation of the hydroxymethylfuranone (I) yields the aldehyde (II) which is converted into the dichloromethylfuranone (IIIb) by reaction with PCl5.
ChemInform Abstract: Synthesis of Some New Hydrazide Hydrazones, Thiosemicarbazides, Thiadiazoles, Triazoles, and Their Derivatives as Possible Antimicrobials.
Authors: GUERSOY A. + , DEMIRAYAK S. , CESUR Z. , REISCH J. , OETUEK G. +
Published: May 2016

The mercaptoimidazole (I) is coupled with the chloroacetic acids (II) to produce the sulfides (III).