bluuebunny/crossref_metadata_2025 huggingface dataset:
Formowanie się sieci cerkiewnej na przestrzeni dziejów w granicach współczesnego województwa podlaskiego
Authors: Kołbuk Witold
Published: May 2019

Od czasów średniowiecza na terenie współczesnego województwa podlaskiego obecne było wschodnie chrześcijaństwo. Zmienny bieg dziejów politycznych Podlasia oddziaływał w kolejnych stuleciach na możliwość tworzenia się wschodniochrześcijańskiej sieci cerkiewnej. W oparciu o rozproszone materiały źródłowe (archiwalne i biblioteczne) można odtworzyć proces formowania się tej sieci. Między połową XV a końcem XVI w. powstało na terenie współczesnego województwa podlaskiego co najmniej 67 cerkwi prawosławnych. Po unii brzeskiej (1596 r.) większość świątyń przeszła w ręce Cerkwi greckokatolickiej, wybudowano także nowe i w momencie III rozbioru Rzeczypospolitej (1795 r.) na wspomnianym obszarze znajdowało się 109 obiektów cerkiewnych. W okresie przynależności Podlasia do imperium rosyjskiego (do 1915 r.) Cerkiew greckokatolicka została zlikwidowana, a jej świątynie przekazano Rosyjskiemu Kościołowi Prawosławnemu. W tym czasie wzniesiono jeszcze około 100 sakralnych obiektów cerkiewnych. Dramatyczne wydarzenia obu wojen światowych i derusyfikacja ziem wschodnich w Polsce w okresie międzywojennym skutkowały likwidowaniem świątyń na Podlasiu – w 1945 r. było już tylko 149 cerkwi. Niewielki wzrost liczby sakralnych obiektów wschodniego chrześcijaństwa nastąpił w czasie rządów komunistów (1944–1989) – ich liczba sięgnęła 169. Dopiero po upadku systemu komunistycznego na terenie współczesnego województwa podlaskiego liczba tych świątyń znacznie wzrosła (205 w 2015 r., kilka znajduje się ciągle w budowie). Większość omawianych obiektów stanowi unikatowe przykłady architektury sakralnej (głównie drewnianej).
The Effects of Chronical Noise-Exposure on Hearing Ability, Psychological, and Mental Attitude of Workers in Automotive Industry
Authors: Ali Mohammadi Iraj , Ahmadi kanrash Fakhradin , Abolghasemi Jamileh , Rahmani Kazem
Published: May 2019

Introduction: Noise is considered as a physical hazard that seriously threatens human health in industrial environments. It is also the most important and influential harmful physical factor in workplace that can affect the individuals’ lifestyle and job. The present study aimed to determine the effects of chronic noise on the hearing ability as well as psychological and mental attitudes of workers in the workplace.
Methods: This descriptive-analytical study was carried out to measure the sound intensity received by the individuals' ears at an 8-hour equivalent level based on ISO 9612: 2009 standard, using the Testo device (model CEL-815). Annoyance (negative mental attitude to work environment) was also measured using a questionnaire containing 11 questions.  Furthermore, the Stroop and Tower of London (TOL) tests were applied to investigate the cognitive performance. 
Results: A total of 300 people with the mean age of 36.03 ± 3.79 were included in this study. The results clearly showed a significant relationship between cognitive indicators and hearing loss (P < 0/05 ). A significant relationship was also observed between annoyance and hearing level at different sound frequencies (P < 0/05). Besides, the results of the Stroop, Tower of London, and cognitive performance tests had a significant relationship with the annoyance caused by chronic exposure to noise (P < 0/05).
Conclusion: The results of this study clearly showed the positive effect of hearing loss on annoyance and cognitive performance indicators among the workers exposed to chronic noise.
Comparing the Immunity of Genetically and Non-Genetically Modified Rice regarding the Possibility of Gene Transferring to Blood of a Laboratory Animal
Authors: Haji Mohammadi Bahador , EIslami Gilda , Aalaei Mahsa , EhramPoush Mohammad Hassan , Rezvani Mohammad Ebrahim , Fallahzadeh Hossein , Shirdeli Mehrnooush
Published: May 2019

Introduction: Genetically modified plant species are produced by the genetic engineering of agricultural science and the addition of specific genes in their genetic sequences with the aim of optimizing the product and creating desirable traits. This study examined the remains of Cry1A(b) and P35 genes in blood of rats fed with genetically modified rice.
Methods: This experimental and interventional study was conducted on male and female rats Sprague Dawley (SD), which were divided into treatment and control groups according to the type of food received. Each group consisted of 10 rats (5 male and 5 female); the first group consumed 50 percent of the genetically modified rice and the second group consumed 50percent of non- genetically modified rice from the total needed carbohydrate. Blood sampling and DNA extraction were conducted after 90 days of feeding rats with nutritional pattern using a kit. Quantitative and qualitative tests were carried out on the extracted DNA using agarose gel electrophoresis and spectrophotometry, respectively.
Results: Agarose gel electrophoresis was used and the results showed no transgenic genes in the studied blood samples.
Conclusion: The results showed no significant difference between the the treatment and control rats with regard to the presence of transgenic genes of p35 and Cry1A(b). Therefore, the possibility of gene transfer to the organs of rats consuming genetically modified rice was rejected. Results of this study showed no difference between the safety of genetically-modified and non- modified rice with regard to gen transferring.
Effects of Parathion Toxin on Glutamate Dehydrogenase Enzyme Activity and Diabetes Induction
Authors: Jamshidi Hamid Reza , Ebrahimi Elham
Published: May 2019

Introduction: The main propose of this study was to determine the effect of parathion on activity of glutamate dehydrogenase (GDH) as a key enzyme in second phase secretion of insulin and to determine serum glucose levels in rats.
Methods: To conduct the study, 35 rats were randomly divided into five groups (n=7). The serum glucose level of each group was measured and the total average was calculated with a glucometer. The experimental groups (groups 1,2,3,4) received 0.5, 1, 1.5, and 2 mg/kg of parathion pesticide via IP injection; whereas, the control group received no treatment. All rats were kept in similar condition. Serum glucose levels of rats were measured 24h after the final injection. Glutamate dehydrogenase (GDH) activity in rat’s pancreas was measured by GDH activity assay kit and using a spectrophotometer at 570nm.
Result: The levels of glucose in treatment groups significantly increased compared with the control group (P<0.01). The levels of GDH activity in rats increased after receiving  1.5 and 2 mg/kg of parathion pesticides compared with the control group (P<0.01, p<0.05).
Conclusion: Regarding the results, parathion affects the GDH enzyme in the pancreatic islets and leads to insufficient secretion of insulin. Although insulin was increased and increased the intermediates of Krebs cycle, the rate of insulin secretion was not so high  to overcome the increase of glucose caused by parathion organophosphate
A Study on the knowledge, Attitudes and Practice of Diabetic Retinopathy among Patients with Diabetes in Yazd Province
Authors: Gohari Mohsen
Published: May 2019

The abstract not available.
Intracytoplasmic sperm injection outcomes after anti-oxidant treatment in repeated implantation failure
Authors: TANGAL Semih , ÇAĞLAR Gamze Sinem , PABUÇCU Emre Göksan , KESKİN Müge , HALİLOĞLU Ahmet Hakan
Published: May 2019

Objectives:
Aim of this study was to explore the effects of three
months oral anti-oxidant treatment in normozoospermic men with high DNA fragmentation
index (DFI) and recurrent intracytoplasmic sperm injection (ICSI) failures.
Methods: This is a retrospective
analyses of normozoospermic patients with high DFI levels (> 30%) with at least
two unsuccessful ICSI attempts. Among the participants, the study group included
men who had oral anti-oxidant treatment. The men who did not receive any treatment
during the study period were taken as controls. The outcomes of new ICSI cycles
were compared. Results: During the
study period 24 men have used three months of oral anti-oxidant treatment before
a new ICSI cycle whereas the remaining 46 had ICSI-only without any other intervention.
Duration of stimulation, the number of metaphase II oocytes, fertilization
rate and implantation rates were similar between two groups. Although not statistically
significant, cases in anti-oxidant group have slightly better pregnancy rates compared
to ICSI-only group (37.5% vs 19.6%, p > 0.05). Only one case in each group
had abortion.

Conclusions: This study
reveals that there is no statistically significant difference in the ICSI outcomes
of the patients with high DFI levels, following unsuccessful ICSI attempts after
oral anti-oxidant treatment. The possible benefit derived from the anti-oxidant
therapy needs to be clarified with clinical studies with greater study populations.
Fournier gangreninde mortaliteyi öngörmede skorlama sistemlerinin değerlendirilmesi
Authors: ER Sadettin , TOPÇU Ramazan , TİKİCİ Deniz , ÖZDEN Sabri , TEZ Mesut
Published: May 2019

Amaç: Fournier gangreni hastalarında şiddet ve mortaliteyi
öngörmede skorlama sistemlerini değerlendirmeyi amaçladık.Gereç ve Yöntemler: Çalışmaya
dahil edilen 76 hastanın demografik,
klinik ve laboratuvar verileri elektronik ortamda retrospektif olarak
incelendi. Çalışmada her hasta için demografik özellikleri, klinik ve laboratuvar
parametrelerini içeren FGSI, UFGSI ve NFS skorları hesaplandı. Skorların ROC
analizi yapıldı. Analizimiz sonucunda p<0,05 olanlar istatistiksel olarak
anlamlı kabul edildi.Bulgular: Çalışmaya
dahil edilen 76 hastanın 65(%85,5)’i taburcu edilirken, 11(%14,5)’inde
mortalite gelişti. Tüm hastalar, Grup-1: Taburcu edilen hastalar ve Grup-2:
Mortalite gelişenler olarak iki gruba ayrıldı. ROC((receiver operating
characteristic) analizinde; FGSI, UFGSI ve NFS skorları için AUC (Area Under
The Curve=Eğrinin Altında Kalan Alan) sırasıyla 0,890 (%95 CI: 0.785-0.994,
p=0.000), 0,895 (%95 CI: 0.810-0.981, p=0.000) ve 0,867 (%95 CI: 0.733-1, p=0.000)
olarak bulundu.

Sonuç: İdeal
bir skorlama sistemi; bu hastalığı daha iyi anlamak, beklenmedik mortalite
durumlarında hataları tanımlayabilmek ve sağkalıma katkıda bulunabilmeyi
amaçlamalıdır. NFS’nin basit, kolay değerlendirilen parametreler içeren bir
skorlama sistemi olduğunu ve klinik pratikte mortaliteyi değerlendirmede
oldukça faydalı olabileceğini düşünüyoruz.
Zastosowanie systemów informacji geograficznej (GIS) w dydaktyce geograficznej przykład ćwiczeń terenowych „Geografia turyzmu i hotelarstwa”
Authors: Latosińska Jolanta , Nalej Marta
Published: May 2019

Celem artykułu jest przedstawienie możliwości zastosowania Systemów Informacji Geograficznej (GIS) dla celów dydaktycznych na kierunku Turystyka i Rekreacja na przykładzie ćwiczeń terenowych „Geografia turyzmu i hotelarstwa”. Zasięg przestrzenny badań terenowych, prowadzonych w ramach ćwiczeń, obejmował obszar sołectwa Spała. Podczas ćwiczeń zastosowano dwie przestrzenne metody określenia funkcji turystycznej: zdjęcie użytkowania ziemi oraz bonitację punktową. Ćwiczenia zrealizowano z użyciem technologii i narzędzi GIS, w tym oprogramowania ArcGIS 10.4 (desktop) oraz umożliwiającego pracę w chmurze portalu ArcGIS Online. Przeprowadzone ćwiczenia pozwoliły na scharakteryzowanie funkcji turystycznej sołectwa Spała.
Four Smart Steps: Fall Prevention for Community-Dwelling Older Adults
Authors: Minnier Wendy , Leggett Mary , Persaud Indranie , Breda Karen
Published: May 2019

Falls are associated with enormous costs in morbidity and early mortality, as well as loss of safe, independent lifestyles for community-dwelling older adults. The purpose of this quality improvement project was to implement an author-designed, easy-to-remember guide to fall prevention for community-dwelling older adults and enhance their awareness and knowledge of fall risks in the home. A Four Smart Steps Fall Prevention program (exercise, eye exams, home safety, and primary care visits) presented fall prevention education for community-dwelling older adults. The project was implemented at a senior center by registered nurses and evaluated through an anonymous questionnaire. The desired outcome was an increase in safety awareness and knowledge of fall prevention for community-dwelling older adults. Community-dwelling older adults with enhanced education on fall prevention will be more likely to be able to live independently within a safe environment.
Tarifs et tables de cubage d’arbres individuels du pin d’Alep, Pinus halepensis Mill., dans l’Aurès algérien
Authors: Goubi Mostefa , Bentouati Abdallah , Kherchouche Dalila , Sghaier Tahar
Published: May 2019

L’objectif de ce travail est d’élaborer des tarifs de cubage d’arbres individuels de pin d’Alep, Pinus halepensis Mill., de la pinède des Ouled-Yaâgoub en Algérie. Neuf fonctions linéaires et non linéaires ont été ajustées systématiquement sur des données collectées à partir de 340 arbres, représentatifs des différentes classes de diamètre et de hauteur, choisis parmi les arbres abattus dans le cadre des coupes d’exploitation finales dans les chantiers installés dans la zone étudiée. L’approche adoptée pour l’estimation des paramètres des différentes fonctions testées est basée sur la régression, linéaire et non linéaire, selon la technique des moindres carrés ordinaires pondérés. Des analyses numériques et graphiques basées essentiellement sur la distribution des résidus et la précision des tarifs obtenus ont été employées pour comparer les différentes fonctions étudiées. Deux fonctions ont été retenues pour le cubage d’arbres individuels dans la pinède du massif des Ouled-Yaâgoub en Algérie. La première à une entrée exprime le volume en fonction du diamètre de l’arbre à 1,30 m de hauteur, et la seconde à deux entrées exprime le volume en fonction du diamètre à 1,30 m de hauteur et de la hauteur totale. Les coefficients de détermination ajustés et les carrés moyens résiduels obtenus par ces deux fonctions ou tarifs sont respectivement 0,944 et 109,78 dm3 pour la première et 0,977 et 69,69 dm3 pour la seconde. Enfin, pour une gestion efficace du massif des Ouled-Yaâgoub, l’estimation du volume sur pied des arbres de pin d’Alep doit tenir compte de l’objectif souhaité. Le tarif à une entrée, plus rapide à matérialiser, peut être utilisé pour des interventions sylvicoles telles que les éclaircies alors que le tarif de cubage à deux entrées, qui est plus précis, peut être choisi pour des coupes finales dont le bois sera destiné à la vente où des précisions plus importantes sur les volumes produits sont nécessaires.
Structuration de la biodiversité des forêts africaines et changements climatiques : une étude à travers le genre Khaya (Meliaceae)
Authors: Bouka Dipelet Ulrich Gaël
Published: May 2019

Des études paléoécologiques suggèrent que la composition floristique, la structure et la répartition actuelle des forêts denses africaines ont été fortement influencées par la mise en place de gradients écologiques, favorisant la spéciation parapatrique. De plus, lors des changements climatiques passés, certains « refuges forestiers » auraient été peu ou pas affectés par les variations climatiques, favorisant une spéciation allopatrique des espèces forestières. En Afrique, les rôles respectifs de ces deux mécanismes sont encore peu étudiés.Nous abordons cette problématique à travers le genre Khaya (Meliaceae, acajous d’Afrique), un genre modèle dont les espèces présentent des affinités écologiques variables, depuis les savanes arborées jusqu’aux forêts denses humides sempervirentes. La combinaison d’analyses génétiques et morphométriques a permis de mettre en évidence l’existence de plusieurs groupes distincts dans le complexe K. anthotheca, suggérant l’existence de cinq taxons différents. Trois de ces taxons présentent des distributions allopatriques ou parapatriques, et deux d'entre eux se retrouvent localement en sympatrie, dont un taxon nouveau pour la science. Ces taxons présentent des spécificités que l’on peut expliquer tant par des mécanismes de spéciation parapatrique qu’allopatrique, en lien avec les gradients écologiques et les changements climatiques passés. À l’opposé, la présence de deux clusters génétiques de K. ivorensis, dus à un isolement par la distance, ne permet pas de séparer deux taxons mais suggère l’ébauche d’une spéciation qui n’est pas encore aboutie. En effet, les populations des deux clusters partagent certains haplotypes chloroplastiques et mitochondriaux retraçant des histoires évolutives différentes pour chaque marqueur.L’existence de plusieurs taxons au sein de K. anthotheca et la confirmation de K. ivorensis en tant que taxon unique et bien séparé ont conduit à la révision taxonomique du genre. La description des taxons a été totalement refondue et une nouvelle clef de détermination est présentée. Ces nouvelles connaissances permettent d’éclairer l’histoire évolutive des acajous du genre Khaya et la structuration de la biodiversité des forêts africaines afin de poser les bases d'une stratégie de conservation et de gestion durable de ces essences très recherchées tant pour leur bois que pour des usages médicinaux.
GROWING DEVELOPING CIVICS LITERACY THROUGH SAINTIFIC LEARNING APPROACH MODEL USING LEARNING MEDIA COMPUTER PRO SHOW GOLD APPLICATION
Authors: Fatahillah Fatahillah , Sudrajat Mulat , Rohmawati Ari
Published: May 2019

Developing Civic Literacy for a citizen of a young country is a pedagogical mission that must be borne by every educator directed by the 2013 Curriculum through the use of Scientific approaches in various learning activities that require learning media that can arouse students' rational and intellectual thinking ability, namely Audio Visual Media namely a media based on multimedia with computer hardware and run based on software programs namely; Pro Gold Show. Researchers intend to carry out an Action Research (Action Research) which aims to examine the Impact of the Use of Scientific Learning-Based Models Using Computer Application Media Pro Gold Show Research will be carried out through three cycles namely planning, acting, observing and Reflection and analyzed by SWOT (Strenghts Weakness Opportunities Threats). This study was conducted to develop a hypothetical model using a qualitative approach, while the results of the study showed that the Action Model had the power: Can provide a more effective and simple transformation of knowledge through a series of stages of Action, Weaknesses: Learning using an old style that is Cross Curricular will hinder innovation and improvisation: Opportunities: Still open Innovation and Improvisation in its development; Threat: Creativity that is not formed due to the lack of ability of the Teacher will result in actions in learning to be in vain.
A randomised-placebo controlled study into the efficacy of working memory training in chronic obstructive pulmonary disease: the study protocol
Authors: Mount Sarah , Houben Katrijn , Gosker Harry , Beers Martijn van , Schuurman Lisanne , Franssen Frits , Janssen Daisy , Schols Annemie
Published: May 2019

Background

General cognitive impairment is highly prevalent in patients with chronic obstructive pulmonary disease (COPD). Domain-specific cognitive impairments include deficits in working memory (WM), cognitive flexibility, verbal memory, planning and psychomotor speed. These impairments may be associated with poor health behaviours, such as a sedentary lifestyle and low-quality diet. Cognitive training may reverse these effects. Recent evidence suggests that WM training is linked to self-control and, indirectly, to improved lifestyle behaviour including increased physical activity. We aim to investigate the efficacy of WM training (WMT) in patients with COPD on cognitive performance, cognitive stress susceptibility and perception, self-control, and adherence to personalised physical activity and dietary behaviour goals.

Methods

A double blind, placebo-controlled randomised trial will be conducted in 60 patients with COPD. The trial will consist of two phases; 12 weeks of active WM training or sham training followed by 12 weeks of maintenance. Prior to the WMT, before the first phase, participants in both the sham (n=30) and training group (n=30) will set dietary and physical activity goals based on their dietary intake and physical activity profile using validated tools. Cognitive performance will be examined using the Cambridge Neuropsychological Test Automated Battery. The primary outcome of this study will be change in cognitive performance. Secondary outcomes will be self-control (impulsivity), compliance, stress susceptibility and perception, change in dietary intake and daily physical activity level and pattern.

Discussion

This trial will attempt to determine if cognitive performance can be improved in patients with COPD by WMT. Moreover, WM plays a key role in self-regulation of behaviour, i.e. resisting hedonic impulses in exchange for more deliberate evaluations and the achievement of long-term goals. Therefore, we expect that WMT will also have a positive impact on health behaviours.

Registration

Clinicaltrials.gov registration: NCT03073954
Cognitive effect of cilostazol in post stroke cognitive impairment: a prospective study
Authors: Huang Ling-Chun , Hsieh Sun-Wung , Chen Chun-Hung , Yang Yuan-Han
Published: May 2019

Background

Whether antiplatelet agents have a preventive effect on cognitive function after ischemic stroke remains unknown. This study examined the potential effect of cilostazol, an antiplatelet agent and cyclic adenosine monophosphate phosphodiesterase 3 inhibitor, on cognitive impairment after stroke in an Asian population.

Methods

A total of 45 patients using cilostazol (100 mg) twice per day were enrolled as the study group and 45 patients using aspirin (100 mg) or clopidogrel (75 mg) daily were enrolled as the control group. Mini-mental state examination and Cognitive Assessment Screening Instrument were administered at the start of the study and after 6 months. Multiple logistic regression analysis was used to estimate the association between the cognitive change and cilostazol use.

Results

Overall, 60-70% of the patients improved their cognition after 6 months follow up. No significant differences were observed in the cognitive change between the cilostazol and control groups. However, the cilostazol group appeared to perform better in the fluency, language and judgment subdomains.

Conclusions

In the current study, the clinical course of post stroke cognitive changes was described. Although cilostazol did not make a significant difference in cognitive change after ischemic stroke, it may improve fluency, language and judgment subdomains. These findings should be examined further in randomized clinical trials.
Functional dyspepsia: from pathogenesis to therapeutic aspects
Authors: Dicheva D. T. , Subbotina Yu. S. , Bektemirova L. G. , Andreev D. N.
Published: May 2019

Functional dyspepsia (FD) is one of the most common gastroenterological diseases. The article presents modern views on the pathogenesis of the disease. It is shown that disorders of motor skills (retardation of voiding function, disturbance of relaxation accommodation) and stomach sensitivity (visceral hypersensitivity to stretching) are considered to be one of the main pathophysiological mechanisms of FD. The authors present a modern algorithm of treatment of patients with FD, based on the clinical recommendations of the Rome Consensus IV revision (2016) and the Russian Gastroenterological Association (2017). The strategy of differentiated use of pharmaceuticals for different variants of FD is considered.
Multi-component infusion hepatoprotectors for liver damage
Authors: Sas E. I. , Grinevich V. B.
Published: May 2019

Drug-induced liver injuries (DILI) remain today one of the most pressing problems not only in gastroenterology, but also in all therapy. Up to 10% of the changes in laboratory parameters can be attributed to the use of drugs. The importance of DILI has increased significantly in recent years, due to the increase in the number of over-the-counter medicines on the pharmaceutical market, as well as non-compliance with the methods and modes of administration. There are common links in the pathogenesis of DILI, including hypoxia, de-energization (deficit of ATP production), damage to hepatocyte membranes and suppression of antioxidant protection. Therefore, pathogenetic pharmacotherapy and prevention of liver damage are based on drugs with an action mechanism aimed at eliminating one or more links in the pathogenesis. One of these drugs is Remaxol, which includes antihypoxantantioxidants of metabolic type: natural metabolites, substrates and cofactors involved in energy metabolism. Remaxol was administered to 30 patients with duodenal ulcer (DU) in the acute phase in addition to the main eradication therapy in the case of cytolytic syndrome by the end of the first week of therapy intravenously dripping at a rate of 40-60 drops/min in a daily dose of 400 ml for 10 days a day. Against the background of Remaxol application, the patients with DILI had stabilization of the main biochemical parameters: the level of AST, ALT, direct bilirubin, GGT and alkaline phosphatase. These changes were accompanied by a positive dynamics of the general state of health. The use of Remaxol in patients with DILI will allow to achieve clinical and biochemical remission, preventing the development of severe liver damage, and contributes to the preservation of the recommended duration of treatment of the underlying disease.
Molecular and phenotypic characterization of diarrheagenic Escherichia coli isolated from groundwater in rural areas in southern Brazil
Authors: da Silva Caroline Rodrigues , Sanches Matheus Silva , Macedo Kawana Hiromori , Dambrozio Angélica Marim Lopes , da Rocha Sergio Paulo Dejato , Navarro Armando , Pelayo Jacinta Sanchez
Published: May 2019

Water-borne diseases like diarrheagenic Escherichia coli (DEC)-induced gastroenteritis are major public health problems in developing countries. In this study, the microbiological quality of water from mines and shallow wells was analyzed for human consumption. Genotypic and phenotypic characterization of DEC strains was performed. A total of 210 water samples was analyzed, of which 153 (72.9%) contained total coliforms and 96 (45.7%) E. coli. Of the E. coli isolates, 27 (28.1%) contained DEC genes. The DEC isolates included 48.1% Shiga toxin-producing E. coli (STEC), 29.6% enteroaggregative E. coli (EAEC), 14.9% enteropathogenic E. coli (EPEC), 3.7% enterotoxigenic E. coli (ETEC), and 3.7% enteroinvasive E. coli (EIEC). All the STECs had cytotoxic effects on Vero cells and 14.8% of the DEC isolates were resistant to at least one of the antibiotics tested. All DEC formed biofilms and 92.6% adhered to HEp-2 cells with a prevalence of aggregative adhesion (74%). We identified 25 different serotypes. One EPEC isolate was serotype O44037:H7, reported for the first time in Brazil. Phylogenetically, 63% of the strains belonged to group B1. The analyzed waters were potential reservoirs for DEC and could act as a source for infection of humans. Preventive measures are needed to avoid such contamination.
Advances in Cyanine - Amino Acid Conjugates and Peptides for Sensing of DNA, RNA and Protein Structures
Authors: Šmidlehner Tamara , Rožman Andrea , Piantanida Ivo
Published: May 2019

Small molecule spectrophotometric probes for DNA/RNA and proteins are of the utmost
importance for diagnostics in biochemical and biomedical research. Both, naturally occurring and synthetic
probes, often include peptide sequence responsible for the selectivity toward the particular target;
however, commercially available dyes are restricted to single point attachment to the peptide (having
one reactive group). Here presented are our recent advances in the development of novel amino acidfluorophore
probes, with the unique characteristic of free N- and C-terminus available for incorporation
at any peptide backbone position. Intriguingly, already monomeric amino acid-fluorophores showed
recognition among various DNA/RNA, whereby steric impact and contribution of halogens is systematically
studied. Moreover, some dyes revealed intracellular mitochondria specificity. Further, several
hetero-dimeric chromophore systems were prepared, demonstrating that synergistic effect can lead to
simultaneous DNA, RNA and protein fluorimetric recognition, combined with enzyme inhibition. Also,
homodimeric cyanines equipped with chlorine revealed intriguing DNA/RNA selectivity in respect to
well-known parent TOTO and YOYO dyes.
Large Unrepaired Aortopulmonary Window Presenting in Adulthood
Authors: Dev Munish , Sharma Madhurima , Rana Naresh
Published: May 2019

Background:

Aortopulmonary window is an uncommon congenital heart disease, with untreaAortopulmonary window is an uncommon congenital heart disease, with
untreated cases not surviving beyond childhood. However, very rarely it can present in adult patients
with features of pulmonary hypertension. Clinically these patients cannot be differentiated
from other more common conditions with left to right shunt. Transthoracic echocardiography if
performed meticulously, can depict the defect in aortopulmonary septum.ted cases
not surviving beyond childhood. However, very rarely it can present in adult patients with features of pulmonary hypertension. Clinically these patients cannot be differentiated from other more common conditions with left to right shunt. Transthoracic echocardiography if performed meticulously, can depict the defect in aortopulmonary septum. We report a case of large unrepaired aortopulmonary window in a 23 years old patient, diagnosed on transthoracic echocardiography.

Results:

We report a case of large unrepaired aortopulmonary window in a 23 years old patient, diagnosed
on transthoracic echocardiography.
Cost-effective technology of temporary setting trains aside from the traffic
Authors: Sotnikov E. A. , Kholodnyak P. S.
Published: May 2019

The article determines main factors of the need for modern conditions of temporary setting aside trains from the traffic, which require consideration of this operation not as an emergency forced measure, the need for which arises because of operational personnel errors, but as one of the elements of the transportation process technology that require it rational organization. These factors are: formation of large unloading areas in seaports taking into account recurring difficulties in its work, technical equipment failures and traffic safety violations, daily irregularity of train operation, etc. Principles of building a rational strategy for temporary setting aside trains from traffic are considered. It makes provision for: using the capabilities of the operational area infrastructure as a whole for set aside trains, impermissibility of reducing the carrying capacity of previous sections of the difficult section below its carrying capacity as a result of set aside trains, selecting stations for set aside trains based on feasibility studies.Use of a cost-effective strategy for the temporary setting trains from traffic in the event of operational difficulties will minimize the expenses of the JSC “Russian Railways” related to the need to carry out this element of the transportation process technology.
PRIVATE TECHNIQUE OF FORMATION OF REQUIREMENTS TO INFORMATION PROTECTION SYSTEMS FROM UNAUTHORIZED ACCESS TO AUTOMATED BATH SYSTEMS USING GENETIC ALGORITHM
Authors: Drovnikova I. G. , Zmeev A. A. , Rogozin E. A.
Published: May 2019

Objectives.Analysis of the existing methodology for the formation of requirements for information protection systems (GIS) from unauthorized access (NSD) to automated systems (AS) revealed a number of significant flaws, the main of which is the following: despite the fact that the considered method undoubtedly has theoretical significance, the same time, it can not claim practical value. This is due to the fact that in this methodology, the studies were carried out not on a specific standard (widely used certified according to the regulations of the Federal Service for Technical and Export Control of Russia) GIS, and the data on threats of unauthorized access given in it do not correspond to reality (morally obsolete), but therefore require a significant upgrade. Accepting the existing methodology as a baseline, the purpose of the article is to develop a private method of forming requirements for GIS from unauthorized access to the AU, which has practical value and allows you to formulate quantitative requirements for a wide class of certified GIS.

Method.When writing the article, the methods of system analysis, evolutionary modeling, probability theory and mathematical statistics, mathematical apparatus for modeling dynamic discrete networks (E-networks), and theory of algorithms were used. The methodological basis is a systematic approach.

Result.A private methodology has been developed that determines the parameters of the symbolic genetic algorithm (GA) for creating a software package for analysis, evolutionary modeling, and forming quantitative requirements for GIS from un-authorized access to speakers using the Matlab 13 application software to implement GA in the Optimization toolbox programming environment.

Conclusion.The proposed private method of forming requirements for GIS from unauthorized access in the AU using GA has a theoretical significance, practical value and allows you to formulate quantitative requirements for a wide class of AS certified in a certain class of security in accordance with the requirements of current regulatory documentation.
DEVELOPMENT OF THE TECHNIQUE OF OPERATION OF GEOTHERMAL SYSTEMS WHEN EXTRACTING ASSOCIATED GASES
Authors: Akhmedov G. Ya. , Kurbanismailova A. S.
Published: May 2019

Objectives.The aim of the study is to develop a method of operating geothermal energy systems in the mode without scaling when disposing of flammable gases with geothermal water in wells with a low gas factor.

Method.The studies were conducted on the basis of analyzing the content of associated flammable gases in the underground thermal mineral waters of the North Caucasus and Ciscaucasian deposits and assessing the possibility of their utilization and use for heating and hot water supply. In this case, the laws of dissolution and desorption of methane and carbon dioxide from groundwater solutions with the content of scale-forming components, in particular, calcium carbonate, are used.

Result.On the basis of the conducted research, it was found that the operation of g eothermal systems in the power industry should be carried out after preliminary withdrawal of the maximum possible amount of associated flammable gases from a water solution, while maintaining the content of carbon dioxide in water at a level above the equilibrium value. The scheme of the effective operation of thermal distribution stations with the prevention of carbonate deposits in them is given by using the products of associated gas combustion in the waste water when it is pumped back into the aquifer.

Conclusion.As a result of the research conducted, a method of operating geothermal energy systems in a non-salt-scale mode has been developed for utilization of combustible gases associated with geothermal water. It has been established that in order to accelerate the dissolution of carbon dioxide in water to stabilize it before entering heat-exchange equipment, it is advisable to increase the partial pressure of carbon dioxide to values exceeding by an order of magnitude the equilibrium at a given temperature. At the same time, before pumping waste water back into the aquifer, excess carbon dioxide is removed from the water.
NATURAL TESTS OF THE EXPERIMENTAL SAMPLE OF THE THERMOELECTRIC SYSTEM, BASED ON JOINT USE OF HIGH-CURRENT THERMOELECTRIC BATTERIES AND ALL-METAL THERMAL CONDUCTORS
Authors: Evdulov D. V. , Ismailov T. A. , Kazumov R. Sh. , Sarkarov T. E.
Published: May 2019

Objectives. The aim of the article is to develop and study a thermoelectric system based on the combined use of high-current thermoelectric batteries and heat pipelines made of high-heatconducting material (e.g. copper or aluminum), to conduct full-scale experimental studies of the experimental sample of thermal power plants.

Method. The design of the device of the experimental stand of the prototype on the basis of the combined use of high-current thermoelectric batteries and heat pipelines made of high-heat-conducting material is presented. The technique of full-scale tests of the prototype on a specially created laboratory bench to confirm the adequacy of the results of thermal power plants.

Result. Temperature changes in different points of thermal power plants at fixed and different supply currents, temperature changes at the end of the heat pipeline in time at different supply currents of thermal power plants are investigated. The comparison of experimental and calculated data of the prototype is carried out.

Conclusion. The results of experimental studies have shown the effectiveness of the developed thermoelectric system for remote separation of the cold source and the cooling object. It is shown that it is possible to increase the efficiency of thermal power plants with the combined use of high-current batteries and heat pipelines made of high-heat-conducting material.
The Role of Financial Performance in Mediating The Effect of Good Corporate Governance on Financial Distress
Authors: Widhiastuti Ratieh , Nurkhin Ahmad , Susilowati Nurdian
Published: May 2019

AbstractThis research aims to study the effect of good corporate governance on financial distress directly and mediated by financial performance. The study population was a manufacturing company listed on the Indonesia Stock Exchange (IDX) in 2016. The study sample was determined using the purposive sampling method, which produced 137 companies that met the requirements. The research data uses secondary data in the form of financial statements and annual reports of manufacturing companies obtained through the Indonesia Stock Exchange website. The analytical tool to test the research hypothesis is Analysis of Moment Structures (AMOS). The results of the study show that there is no direct and indirect impact on corporate governance to financial difficulties; while financial performance has a negative impact on financial difficulties. Keywords: Financial Performance, Good Corporate Governance, Financial DistressPeran Financial Performance dalam Memediasi Pengaruh Good Corporate Governance Terhadap Financial DistressAbstrakTujuan penelitian ini adalah untuk mengetahui pengaruh good corporate governance terhadap financial distress baik secara langsung maupun dengan dimediasi oleh financial performance. Populasi penelitian adalah perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) pada tahun 2016. Sampel penelitian ditentukan dengan menggunakan metode purposive sampling, yang menghasilkan 137 perusahaan yang memenuhi syarat. Data penelitian menggunakan data sekunder berupa laporan keuangan dan annual report perusahaan manufaktur yang diperoleh melalui website Indonesia Stock Exchange. Alat analisis untuk menguji hipotesis penelitian yaitu Analysis of Moment Structures (AMOS). Hasil penelitian menunjukkan good corporate governance tidak berpengaruh baik secara langsung maupun tidak langsung terhadap financial distress; sedangkan financial performance berpengaruh negatif signifikan terhadap financial distress. Kata kunci: Financial Performance, Good Corporate Governance, Financial Distress
Teachers and learners in a time of big data
Authors: Buchanan Rachel , McPherson Amy
Published: May 2019

Policy and technological transformation have coalesced to usher in massive changes to educational systems over the past two decades. Teachers’ roles, subjectivities and professional identities have been subject to sweeping changes enabled by sophisticated forms of governance. Simultaneously, students have been recast as ‘learners’; like teachers, learners have become subject to new forms of governance, through technological surveillance and datafication. This paper focuses on the intersection of the metrics driven approach to education and the political as a way to re-think the future of schooling in more explicitly philosophical terms. This exploration starts with a critical examination of constructions of teachers, learners and the digital data-driven educational culture in order to explicate the futures being generated. The trajectory of this future is explored through reference to the techno-educational models currently being developed in Silicon Valley. Drawing on Deleuze’s notion of control societies we contribute to the ongoing philosophical investigation of the datafication of education; a necessary discussion if we are to explore the future implications of schooling in a technologically saturated world. We present consideration of the past, present and future, as three ways of considering alternatives to a datafied education system. Alternative conceptualisations of the future of schooling are possible which offer ways of understanding and politicising what happens when we impose data-driven accountabilities into people’s lives.
The evolution of learning: Post-pedagogical lessons for the future university
Authors: Parsell Mitch , Chinchen Christine
Published: May 2019

This article offers a post-pedagogical image of universities. We explore two main purposes of university education: creating an educated public and preparing learners for their future careers. This exploration draws on philosophers Barnett, MacIntyre and Nussbaum. We then utilise a series of reports from The Foundation for Young Australians to offer insights into the changing nature of society, technology, and worklife. The evolution of models or theories of learning sets the scene for the framework for how to structure the future university—a post-pedagogical learning institution in which educators are learning specialists, learners are engaged in meaningful and critical thinking, learning and acting.
Education as the practice of freedom, from past to future: Student movements and the corporate university
Authors: Hush Anna , Mason Andy
Published: May 2019

As contemporary universities become increasingly deregulated and neoliberalised structures, how is grassroots student political organising to adapt? What role could student organisers, working in coalition with academics, unions and communities, play in shaping the Future University? We argue that student organising has an even more crucial place in the site of the neoliberal university, working against both the corporatisation of the contemporary university, as well as rising neoliberal conditions in the broader communities within which tertiary education is embedded. These conditions, without doubt, have the potential to stultify student movements by burdening students with ever-increasing debt, and packaging degrees as a commodity with a market-determined value. However, we argue, the neoliberalisation of education also engenders an opportunity for students in shaping the Future University, through grassroots advocacy for staff working conditions, and for critical pedagogies that enable the integration of transformative social justice movements with academic theory. For us, the Future University is a space that nourishes critical and creative thinking, and produces students that are able to integrate theory with radical praxis. However, for this to be realised, the ideological function of the university, in justifying and naturalising hegemonic power structures, and the very meaning of public education, must be exposed and critiqued from the ground up.
Karl Marx y la cuestión colonial
Authors: Herrera Rodríguez Omar S.
Published: May 2019

Este trabajo es una respuesta a dos críticas desarrolladas por la teoría poscolonial y decolonial a la posición de Karl Marx sobre la cuestión colonial: 1) la idea de que la historia se mueve de manera progresiva y lineal y 2) la idea de que Marx analiza la cuestión de las colonias desde una mirada o posición eurocéntrica; con el fin de demostrar las limitaciones de ambas críticas para la comprensión de la obra de Marx sobre este problema.
The Effect of Commissioners Board Size and Committee Board Size on Disclosure of Corporate Social Responsibility (CSR)
Authors: Hafidzi Achmad Hasan
Published: May 2019

This study aims to analyze the effect of board size and committees size to corporate social responsibilitythrough financial performance. The sample used in this study is secondary data of companies listed LQ-45 Index in 2013-2017 and determined using a purposive sampling method. The data about researchvariables are available in the financial report. The data analysis method is using path analysis. Theresults were showed that the size of commissioners board to corporate social responsibility was significantpositive, size of committees to corporate social responsibility was significant positive relationship, size ofcommissioners board to financial performance was significant positive relationship, size of committeesto financial performance was relationship positive significant, financial performance to corporate socialresponsibility shows a significant positive relationship.
ENHANCING STUDENTS' COMMUNICATION SKILLS THROUGH TREFFINGER TEACHING MODEL
Authors: Alhaddad Idrus , Kusumah Yaya S. , Sabandar Jozua , Dahlan Jarnawi A.
Published: May 2019

This research aims to investigate, compare, and describe the achievement and enhancement of students' mathematical communication skills (MCS). It based on the prior mathematical knowledge (PMK) category (high, medium and low) by using Treffinger models (TM) and conventional learning (CL). This research is an experimental study with the population of all students of Mathematics Education Department who took Discrete Mathematics subject matter of one university in the city of Ternate. The results show that (1) the achievement and enhancement of MCSÂ  students that used  TM are higher than the students learning using CL; (2) Based on the categories of PMK, the achievement and enhancement of MCS of students using TM are also higher than those learning with CL; and (3) There was no interaction effect between learning (TM and CL) and PMK to the achievement and enhancement of MCS of the students.Keyword: Communication Skills, Prior Mathematical Knowledge, Treffinger Model
LEVELING OF CRITICAL THINKING ABILITIES OF STUDENTS OF MATHEMATICS EDUCATION IN MATHEMATICAL PROBLEM SOLVING
Authors: Rasiman Rasiman
Published: May 2019

This research aims to determine the leveling of critical thinking abilities of students of mathematics education in mathematical problem solving. It includes qualitative-explorative study that conducted at University of PGRI Semarang. The generated data in the form of information obtained problem solving question and interview guides. The results are: (1) students who are not critical (LCTA-0) only able to identify the given facts clearly, (2) students are less critical (LCTA-1), students can identify the facts in problems, (3) critical student (LCTA-2), students can identify the fact in problems, revealing the prerequisite knowledge appropriately, solve the problem but still less accurate in every stage, and (4) students are very critical (LCTA-3), students can identify the facts given clearly, mention the concept/ theorem/ prerequisite material. Based on these results, the leveling of students critical thinking abilities can be applied in a lecture at mathematics education.Keywords: leveling, critical thinking, mathematical problemÂ DOI: dx.doi.org/10.22342/jme.61.40