bluuebunny/crossref_metadata_2025 huggingface dataset:
Insulin-like Androgenic Gland Hormone Induced Sex Reversal and Molecular Pathways in Macrobrachium nipponense: Insights into Reproduction, Growth, and Sex Differentiation
Authors: Cai Pengfei , Zhang Wenyi , Jiang Sufei , Xiong Yiwei , Yuan Huwei , Gao Zijian , Gao Xuanbing , Ma Cheng , Zhou Yongkang , Gong Yongsheng , Qiao Hui , Jin Shubo , Fu Hongtuo
Published: September 2023

This study investigated the potential to use double-stranded RNA insulin-like androgenic gland hormone (dsIAG) to induce sex reversal in Macrobrachium nipponense and identified the molecular mechanisms underlying crustacean reproduction and sex differentiation. The study aimed to determine whether dsIAG could induce sex reversal in PL30-male M. nipponense during a critical period. The sex-related genes were selected by performing the gonadal transcriptome analysis of normal male (dsM), normal female (dsFM), neo-female sex-reversed individuals (dsRM), and unreversed males (dsNRM). After six injections, the experiment finally resulted in a 20% production of dsRM. Histologically, dsRM ovaries developed slower than dsFM, but dsNRM spermathecae developed normally. A total of 1718, 1069, and 255 differentially expressed genes were identified through transcriptome sequencing of the gonads in three comparison groups, revealing crucial genes related to reproduction and sex differentiation, such as GnRHR, VGR, SG, and LWS. Principal Component Analysis (PCA) also distinguished dsM and dsRM very well. In addition, this study predicted that the eyestalks and the “phototransduction-fly” photoperiodic pathways of M. nipponense could play an important role in sex reversal. The enrichment of related pathways and growth traits in dsNRM were combined to establish that IAG played a significant role in reproduction, growth regulation, and metabolism. Finally, complete sex reversal may depend on specific stimuli at critical periods. Overall, this study provides valuable findings for the IAG regulation of sex differentiation, reproduction, and growth of M. nipponense in establishing a monoculture.
Comparison of Transcriptome between Tolerant and Susceptible Rice Cultivar Reveals Positive and Negative Regulators of Response to Rhizoctonia solani in Rice
Authors: Yang Xiurong , Yan Shuangyong , Li Yuejiao , Li Guangsheng , Sun Shuqin , Li Junling , Cui Zhongqiu , Huo Jianfei , Sun Yue , Wang Xiaojing , Liu Fangzhou
Published: September 2023

Rice (Oryza sativa L.) is one of the world’s most crucial food crops, as it currently supports more than half of the world’s population. However, the presence of sheath blight (SB) caused by Rhizoctonia solani has become a significant issue for rice agriculture. This disease is responsible for causing severe yield losses each year and is a threat to global food security. The breeding of SB-resistant rice varieties requires a thorough understanding of the molecular mechanisms involved and the exploration of immune genes in rice. To this end, we conducted a screening of rice cultivars for resistance to SB and compared the transcriptome based on RNA-seq between the most tolerant and susceptible cultivars. Our study revealed significant transcriptomic differences between the tolerant cultivar ZhengDao 22 (ZD) and the most susceptible cultivar XinZhi No.1 (XZ) in response to R. solani invasion. Specifically, the tolerant cultivar showed 7066 differentially expressed genes (DEGs), while the susceptible cultivar showed only 60 DEGs. In further analysis, we observed clear differences in gene category between up- and down-regulated expression of genes (uDEGs and dDEGs) based on Gene Ontology (GO) classes in response to infection in the tolerant cultivar ZD, and then identified uDEGs related to cell surface pattern recognition receptors, the Ca2+ ion signaling pathway, and the Mitogen-Activated Protein Kinase (MAPK) cascade that play a positive role against R. solani. In addition, DEGs of the jasmonic acid and ethylene signaling pathways were mainly positively regulated, whereas DEGs of the auxin signaling pathway were mainly negatively regulated. Transcription factors were involved in the immune response as either positive or negative regulators of the response to this pathogen. Furthermore, our results showed that chloroplasts play a crucial role and that reduced photosynthetic capacity is a critical feature of this response. The results of this research have important implications for better characterization of the molecular mechanism of SB resistance and for the development of resistant cultivars through molecular breeding methods.
Recent Mechanistic Studies in Allergic Diseases
Authors: Sindher Sayantani B. , Sharma Reyna , Yarlagadda Medha , Chin Andrew R. , Chinthrajah R. Sharon
Published: September 2023

Allergic diseases, such as food allergies, asthma, and allergic rhinitis, continue to present a significant challenge for a broad cross-section of the population, despite recent advancements in their treatment and prevention [...]
Endothelial Dysfunction in Systemic Sclerosis
Authors: Patnaik Eshaan , Lyons Matthew , Tran Kimberly , Pattanaik Debendra
Published: September 2023

Systemic sclerosis, commonly known as scleroderma, is an autoimmune disorder characterized by vascular abnormalities, autoimmunity, and multiorgan fibrosis. The exact etiology is not known but believed to be triggered by environmental agents in a genetically susceptible host. Vascular symptoms such as the Raynaud phenomenon often precede other fibrotic manifestations such as skin thickening indicating that vascular dysfunction is the primary event. Endothelial damage and activation occur early, possibly triggered by various infectious agents and autoantibodies. Endothelial dysfunction, along with defects in endothelial progenitor cells, leads to defective angiogenesis and vasculogenesis. Endothelial to mesenchymal cell transformation is another seminal event during pathogenesis that progresses to tissue fibrosis. The goal of the review is to discuss the molecular aspect of the endothelial dysfunction that leads to the development of systemic sclerosis.
Presence of Adenomyosis Impairs Clinical Outcomes in Women Undergoing Frozen Embryo Transfer: A Retrospective Cohort Study
Authors: Sachs-Guedj Noémie , Coroleu Buenaventura , Pascual María Ángela , Rodríguez Ignacio , Polyzos Nikolaos P.
Published: September 2023

(1) Background: The presence of adenomyosis among pregnant patients has been associated with a higher incidence of miscarriage and pregnancy complications. Although the role of adenomyosis in women undergoing in vitro fertilization (IVF) was investigated in several studies and demonstrated a potentially detrimental effect on live birth rates following IVF, most of them were small studies in which the adenomyosis diagnosis was not confirmed based on solid ultrasonographic criteria. (2) Methods: 3503 patients undergoing their first blastocyst frozen transfer through a hormonal replacement (HRT) FET cycle. Among them, 140 women had a confirmed diagnosis of adenomyosis based on the MUSA criteria. (3) Results: Adenomyosis patients were more likely to proceed with deferred FET compared with no-adenomyosis women (p = 0.002) and were significantly more likely to be treated with GnRH agonist pre-treatment (2 months) (p < 0.001). The presence of adenomyosis significantly decreased the clinical pregnancy rates (aOR 0.62, 95% CI: 0.39–0.98, p = 0.040) and live birth rates (aOR 0.46, 95% CI: 0.27–0.75, p = 0.003) and significantly increased the miscarriage rates (aOR 2.13, 95% CI: 0.98–4.37, p = 0.045). Multivariable logistic regression adjusting for age, autologous or donor oocytes, PGT-A, deferred FET, serum progesterone levels the day before FET, GnRH agonist pre-treatment, number of embryos transferred, and adenomyosis demonstrated that the use of the GnRH agonist protocol did not decrease or increase the miscarriage rate, clinical pregnancy rate, or live birth rate. (4) Conclusions: The presence of adenomyosis had a significant negative impact on the clinical outcomes of patients undergoing FET and was associated with higher miscarriage, lower clinical pregnancy, and live birth rates. GnRH agonist pre-treatment does not appear to improve clinical outcomes.
Market Liquidity Estimation in a High-Frequency Setup
Authors: Avdiu Kujtim
Published: September 2023

This article deals with the identification of a superior forecasting method for market liquidity using a calibrated Heston model for the bid/ask price path simulation instead of a standard Brownian motion, as well as a compound Poisson process and inverse transform sampling for the generation of the bid/ask volume distribution. We show that the simulated trading volumes converge to one single value, which can be used as a liquidity estimator, and find that the calibrated Heston model as well as the inverse transform sampling are superior to both the use of standard Brownian motion and compound Poisson process.
Biblical Kingship, Catholic Theology, and the Rights of Indians in the Opening of Las Casas’s Short Account
Authors: Salonia Matteo
Published: September 2023

This article introduces the key issues and scope of the 16th-century debate over the rights of the native American peoples encountered by Columbus and the Castilian conquistadores. The historic attempt by theologians and missionaries to limit imperial expansion and to defend the dignity of conquered peoples is an example of Western self-criticism and a fundamental contribution of the Catholic Church to the slow emergence of human rights discourses. This article then focuses on the first pages of Bartolomé de Las Casas’s Short Account of the Destruction of the Indies, a text that played a pivotal role in the formation of the Black Legend against Spain, but also in the drafting of the Leyes Nuevas (New Laws) of 1542. While the Short Account’s hyperbolic and explosive prose are well-known, its religious roots can be detected in the prologue and preface, with their discussion of biblical kingship, virtuous Indians, mortal sin, and (un)Christian behavior.
ArtEMon: Artificial Intelligence and Internet of Things Powered Greenhouse Gas Sensing for Real-Time Emissions Monitoring
Authors: Yavari Ali , Mirza Irfan Baig , Bagha Hamid , Korala Harindu , Dia Hussein , Scifleet Paul , Sargent Jason , Tjung Caroline , Shafiei Mahnaz
Published: September 2023

Greenhouse gas (GHG) emissions reporting and sustainability are increasingly important for businesses around the world. Yet the lack of a single standardised method of measurement, when coupled with an inability to understand the true state of emissions in complex logistics activities, presents enormous barriers for businesses to understanding the extent of their emissions footprint. One of the traditional approaches to accurately capturing and monitoring gas emissions in logistics is through using gas sensors. However, connecting, maintaining, and operating gas sensors on moving vehicles in different road and weather conditions is a large and costly challenge. This paper presents the development and evaluation of a reliable and accurate sensing technique for GHG emissions collection (or monitoring) in real-time, employing the Internet of Things (IoT) and Artificial Intelligence (AI) to eliminate or reduce the usage of gas sensors, using reliable and cost-effective solutions.
A Two-Stage Distributed Task Assignment Algorithm Based on Contract Net Protocol for Multi-UAV Cooperative Reconnaissance Task Reassignment in Dynamic Environments
Authors: Wang Gang , Lv Xiao , Yan Xiaohu
Published: September 2023

Multi-UAV systems have been widely used in reconnaissance, disaster relief, communication, and other fields. However, many dynamic events can cause a partial failure of the original mission during the mission execution process, in which case task reassignment should be carried out. How to reassign resources and tasks in multi-dynamic, multi-target, and multi-constraint events becomes a core issue in the enhancement of combat efficiency. This paper establishes a model of multi-UAV cooperative reconnaissance task reassignment that comprehensively considers various dynamic factors such as UAV performance differences, size of target areas, and time window constraints. Then, a two-stage distributed task assignment algorithm (TS-DTA) is presented to achieve multi-task reassignment in dynamic environments. Finally, this paper verifies the effectiveness of the TS-DTA algorithm through simulation experiments and analyzes its performance through comparative experiments. The experimental results show that the TS-DTA algorithm can efficiently solve the task reassignment problem in dynamic environments while effectively reducing the communication burden of UAV formations.
Biofertilizante “biol”: caracterización física, química y microbiológica
Authors: Gil Ramírez Luis Arturo , Leiva Cabrera Frans Allinson , Lezama Escobedo Martha Karina , Bardales Vásquez Cecilia Betzabet , León Torres Carlos Alberto
Published: September 2023

El biol es un abono orgánico de consistencia líquida que se produce en un biodigestor a partir de la fermentación del estiércol de animales y de residuos vegetales, este producto se emplea actualmente como un abono foliar, el cual promueve el desarrollo y crecimiento saludable de diversos cultivos. El objetivo de la presente investigación es evaluar las características físico-químicas y microbiológicas del biol de la Estación Experimental de Bioquímica Aplicada de la Facultad de Ciencias Biológicas de la Universidad Nacional de Trujillo (E.E.B. A–CC.BB-UNT). Para la obtención de los datos se empleó un conductímetro, pH-metro, el método de espectroscopia de absorción atómica, el método de fósforo reactivo, método de Kjeldahl, método azul de metileno y el método del Número más Probable y se obtuvo los siguientes datos:  16,32 mS cm-1 para la conductividad eléctrica, 6.90 para el pH, 290,0 mgL-1, 17,78 mgL-1, 111,7 mgL-1, 153,2 mgL-1,  0,360 mgL-1, 0,080 mgL-1, 1,530 mgL-1, 0,300 mgL-1, 0,140 mgL-1 y 0,017 mgL-1, para el nitrógeno, fosforo, potasio, magnesio, sulfuros, cobre, fierro, manganeso, zinc, y cadmio respectivamente, para plomo y cromo se obtuvo valores inferiores a 0,005 mgL-1 ; así también se reportó ausencia de coliformes totales y fecales (< 1,8 NMP/100 mL). El biol del presente estudio cuenta con las características físico-químicas y microbiológicas para un óptimo crecimiento de diversos cultivos, así también, de ser empleado como una alternativa de solución frente a los agroquímicos convencionales que impactan de una manera negativa el sector agrícola y el medio ambiente.
Plataforma TEAMS y Flipped Learning en estudiantes de la especialidad de inglés de la Universidad Nacional Federico Villareal
Authors: Garvich Ormeño Angie Marlene , Mañaccasa Vásquez María Soledad , Torres Granados Aída Carmen
Published: September 2023

La pandemia causó diversos desafíos en Perú, afectando directamente a las universidades; las cuales para dar continuidad a su oferta educativa adoptaron el uso de diferentes plataformas virtuales. Al respecto, el objetivo fue determinar la relación existente entre el uso de la plataforma TEAMS y Flipped Learning en estudiantes de la especialidad de inglés de la Universidad Nacional Federico Villarreal. El estudio fue no experimental, cuantitativo, de alcance correlacional, con una muestra de 50 estudiantes. Se utilizó la encuesta y 2 cuestionarios validados por expertos, los cuales alcanzaron coeficientes de confiabilidad Alfa de Cronbach de 0,814 y 0,854. Se logró establecer que sí hay una relación lineal, directa y significativa entre las variables con una significancia de Rho de Spearman de 0,389. Se concluyó que ambas variables son importantes para replantear un modelo de aprendizaje más dinámico, activo y colaborativo como Flipped Learning a través de la Plataforma TEAMS.
Estrategia de rentabilidad para mejorar la gestión financiera en la Cooperativas de Ahorro y Crédito
Authors: Carabajo-Castro Luis Agustín , Ochoa-Crespo Juan Diego , Ramírez-Valarezo Carlos Fabián
Published: September 2023

La gestión financiera cumple con un rol de gran importancia dentro de las entidades, cuya finalidad es realizar un proceso de gestión y de gerencia dentro de cada organización. Por lo tanto, el objetivo del estudio fue analizar la gestión financiera como herramienta fundamental y estratégica para mejorar la rentabilidad dentro de las Cooperativas de Ahorro y Crédito. Su metodología se trató de una revisión bibliográfica bajo el enfoque cualitativo con diseño no experimental, análisis descriptivo, donde se aplicó un análisis sintético. Se comprueba que existen falencias e inconsistencias en las Cooperativas de Ahorro y Crédito debido a las carencias de una gestión financiera que ayude a contrarrestar múltiples carencias y mejore la rentabilidad de la empresa. Se concluye que la gestión financiera dentro de las cooperativas mejora notablemente el índice de rentabilidad y cumple con otros roles como cumplir objetivos y metas propuestos por la empresa
Gestión institucional y el engagement laboral de los maestros de las Comunidades Educativas Rechartinas
Authors: Maza Córdova Rossana Zulema
Published: September 2023

El compromiso laboral de los maestros de diferentes comunidades educativas, la manera en cómo se organiza la institución, así como la forma que tienen de relacionarse entre sí, son aspectos importantes en la dinámica educativa. La gestión institucional en relación con la resiliencia y el sentido de pertenencia de trabajadores, quedan vinculados por la misión educativa. El estudio tuvo como objetivo determinar la relación que existe entre gestión institucional y el compromiso laboral de maestros de seis comunidades educativas pertenecientes a una red educativa en Perú. El tipo de investigación fue de tipo descriptiva con enfoque cuantitativo, correlacional de corte transversal. Se aplicaron dos cuestionarios a una muestra de 139 maestros. Se obtuvo que la variable gestión institucional presentó un 26.6% como baja, el 69.8% moderada y el 3.6% alta. Concluyendo que existe una relación significativa y directamente proporcional entre la gestión institucional y el compromiso laboral de los trabajadores.
PENGARUH PENDEKATAN PEMBELAJARAN SAINTIFIK TERHADAP KETERAMPILAN BERBICARA SISWA
Authors: Wahyuningtyas Sri , Chosiah Chosiah , Widayat Edy
Published: September 2023

Pendekatan saintifik pada Kurikulum 2013 merupakan suatu upaya peningkatan kualitas pembelajaran dengan mengedepankan peran aktif siswa dalam seluruh kegiatan pembelajaran. pendekatan saintifik sesuai dengan pendekatan konstruktivis agar siswa mampu secara mandiri pengetahuan dan keterampilan serta sikap melalui pengalaman belajar secara nyata. Peneliti merumuskan tujuan penelitian ini adalah Untuk mengetahui apakah terdapat perbedaan yang signifikan antara keterampilan berbicara siswa dengan menggunakan pendekatan saintifik dan pembelajaran KTSP. Peneliti menggunakan pendekatan penelitian kuantitatif dalam memperoleh data dari sampel penelitian dengan melakukan penelitian eksperimen. Peneliti menggunakan metode pengumpulan data tes dan observasi serta menggunakan instrumen pengumpul data yang telah melalui uji validitas dan reliabilitas instrumen. Dalam melakukan analisis data, peneliti menggunakan rumus statistik korelasi product moment dan t-test untuk menjawab hipotesis penelitian. Berdasarkan hasil perhitungan nilai t pada rumus t-test diperoleh thitung 3,216 dan nilainya jauh lebih besar jika dibandingkan dengan nilai t pada tabel t untuk sampel 30 orang dan taraf signifikan 5% yaitu 1,67. Dengan demikian peneliti sudah dapat membuktikan bahwa terdapat perbedaan yang signifikan antara keterampilan berbicara siswa menggunakan pendekatan saintifik dan keterampilan berbicara siswa menggunakan model pembelajaran KTSP
PENGARUH MODEL PEMBELAJARAN THINK TALK WRITE TERHADAP KEMAMPUAN MENULIS TEKS EDITORIAL
Authors: Nasution Nella Darbiah , Kusyani Diah , Zahara Siti Fatimah
Published: September 2023

This research was conducted to find out how the influence of the think talk write learning model on students' ability to write editorial texts properly and correctly. This research was located at the PAB 1 Helvetia Vocational School, Jl. Veterans Psr. IV Pulo Brayan Medan. The method in this research uses the one-group pretest-posttest experimental model and random sampling technique with a total population of 126 students. The data collection tool used was a written test in the form of an essay. The ability to write editorial texts using the think talk write learning model obtained perfect scores for 6 students with a percentage of 17.6%. The excellent category is 23 students, with a percentage of 67.6%. Enough category as many as 5 students with a percentage of 14.7%. However, for the fewer and significantly fewer categories, none were found. This means that the ability to write editorial texts is at a good level due to the influence of the think-talk write learning model. Thus the hypothesis is accepted, namely that there is an influence of the think talk write learning model on the ability to write editorial texts in XII students of SMK PAB 1 Helvetia in the 2022-2023 academic year.
PELAKSANAAN EKSEKUSI JAMINAN FIDUSIA BERDASARKAN PUTUSAN MAHKAMAH KONSTITUSI NOMOR 18/PUU-XVII/2019)
Authors: Rehulina Rehulina , Sitorus Andi Putra
Published: September 2023

Collateral has a very important function in economic activity in general because providing capital loans from financial institutions (both banks and non-banks) requires the existence of a guarantee, which must be fulfilled by capital seekers if they want to get a loan / additional capital both for the long term and for the long term. short term, such as a fiduciary guarantee. what is the procedure for the execution of fiduciary guarantees after the issuance of the Constitutional Court Decision Number 18/PUU-XVII/2019 This research is normative legal research (legal research). The purpose of this research is to find out how to transfer fiduciary security ownership rights after the issuance of the Constitutional Court Decision Number 18/PUU-XVII/2019 which has so far transferred fiduciary security rights based on Law Number 42 of 1999 concerning Fiduciary Guarantees. Execution of executory titles, sale of objects that are objects of collateral through public auctions, underhand sales carried out based on an agreement between the Giver and the Fiduciary Recipient if in this way the highest price can be obtained that benefits the parties. However, after the issuance of the Constitutional Court's decision 18/PUU-XVII/2019, which provided a legal interpretation that the executive power of the Certificate.
PERLINDUNGAN HUKUM TERHADAP KONSUMEN DALAM PERJANJIAN JUAL BELI ALAT KESEHATAN
Authors: Adi Septian , Syaputri Martika Dini
Published: September 2023

Kepentingan pengaturan kontrak adalah untuk menjamin pertukaran kepentingan, hak dan kewajiban, agar berlangsung secara proporsional bagi para pihak. Dalam pelaksanaan perjanjian jual beli alat-alat kesehatan melibatkan banyak pihak yang saling berinteraksi satu dengan lainnya dengan berbagai macam kepentingan perbedaan-perbedaan tujuan, pandangan, pendapat dari masing-masing pihak akan dapat berpotensi menimbulkan konflik. Konflik tersebut harus segera diselesaikan dengan cara yang tepat untuk meminimalisir pengaruh buruk terhadap keberhasilan jual beli alat-alat keshatan yang dikenal memiliki kompleksitas yang tinggi dan rumit serta menimbulkan persepsi bahwa kedudukan antara penyedia barang sebagai penjual / distributor dan pihak konsumen dalam hal ini rumah sakit / dokter tidak proporsional. Kedudukan antara pihak penjual dan rumah sakit sebagai customer adalah sejajar dan sebagai mitra kerja. Hal ini menunjukkan bahwa ada tujuan untuk mengetahui bagaimana konsep dan standart baku pembuatan kontrak jual beli antara pihak penjual dengan pihak rumah sakit atau dokter sebagai pihak pembeli atau customer serta mengenai asas-asas perjanjian (contract principles) dalam melakukan atau membuat suatu kontrak.
STATUS HUKUM PENGANGKATAN ANAK BAGI ORANG TUA ANGKAT YANG BELUM TERIKAT TALI PERKAWINAN
Authors: Tandilangi Imanuel , - Musakkir , Basri Muhammad
Published: September 2023

This study aims to analyze the consideration of adopting children for adoptive parents who are not yet bound by marriage. This research was conducted using empirical research methods. The data obtained, both primary and secondary data, are categorized according to the type of data. Then the data was analyzed using qualitative methods, namely analyzing data related to the problem under study, then selected based on a logical mind to avoid errors in the data analysis process.The results of this study indicate that: : The considerations for adopting a child for single parents include, among others, wanting to have children, heirs; Wants to have friends for himself or his children; Wants to realize a social sense, compassion for others, who are in difficulty living according to their abilities
PENERAPAN PP NO. 35 TAHUN 2021 (UU CIPTA KERJA) TERHADAP PEMUTUSAN HUBUNGAN KERJA DALAM HUBUNGAN INDUSTRIAL DENGAN ALASAN FORCE MAJEURE
Authors: Avriandi Erick , Sihotang Erikson
Published: September 2023

Peraturan Pemerintah Nomor 35 Tahun 2021 turunan dari Undang-undang Nomor 11 Tahun 2020 Tentang Cipta Kerja. Aturan ini berlaku saat pandemi covid-19, dimana keadaan ini dapat menimbulkan dinamika berbagai aspek hukum, salah satunya terkait masalah tenaga kerja di Indonesia dalam penyelesaian hak dan kewajiban masing pihak saat Pemutusan Hubungan Kerja. Polemik yang terjadi adalah Pemutusan Hubungan Kerja dengan alasan Force Majeure, adapun alasan force majeure masih menimbulkan pro kontra dalam menafsirkan sejauh mana keadaan alasan force majeure dapat dijadikan pijakan perusahaan kepada pekerja dalam melakukan Pemutusan Hubungan Kerja. Adapun ketentuan dalam peraturan pemerintah diatas secara khusus dalam pembahasan perhitungan uang pesangon, yang dalam salah satu pasalnya jika pemutusan hubungan kerja disebabkan alasan perusahaan melakukan efisiensi yang disebabkan perusahaan mengalami kerugian maka pekerja atau buruh akan mendapatkan perhitungan uang pesangon yang lebih rendah dibandingkan dengan pesangon menurut undang-undang nomor 13 tahun 2003 tentang ketenagakerjaan. Tujuan penelitian dalam penulisan ini, untuk mengetahui dan mengkaji lebih jelas bagaimana pengaturan perhitungan uang pesangon sesuai masa kerja bagi pekerja atau buruh yang terkena pemutusan hubungan kerja dalam hubungan industrial sesuai Peraturan Pemerintah Nomor 35 tahun 2021. Untuk memecahkan permasalahan dalam penelitian ini, metode penelitian yang digunakan adalah jenis penelitian hukum normatif, dengan menggunakan bahan-bahan pustaka serta peraturan perundang-undangan sebagai dasar hukum. Sehingga hasil yang diharapkan dalam penelitian ini, jika terjadi perselisihan dalam pemutusan hubungan kerja, perkerja dan pengusaha dapat menyelesaikan secara non litigasi.
ANALISIS HUKUM ATAS TANGGUNG JAWAB NOTARIS TERHADAP TERJADINYA PERBEDAAN SAKSI DALAM SALINAN AKTA DENGAN MINUTA AKTA (STUDI KASUS PUTUSAN M.A NO. 2468-K/PID/2006)
Authors: Munte Pangeran Batara Bonardo
Published: September 2023

The result of the research shows that the evidence inhered to the authentic deed is tangible evidence, formal evidence, or material evidence. In this case, the Panel of Judges of the Supreme Court use material evidence, the truth of the content of authentic deed, because in their legal opinion, in this casse, the problem is the content of the deed not the names of the witnesses. The Notary has issued the copy of the deed with different witnesses from those that are specified in the deed minute which later becomes a claim or complaint from the person who has complaint about the deed made by the Notary. Therefore, the Notary can be sued and is required to take the responsibility in the criminal law (if the criminal count is fulfilled), civil law (if Article 1365 of the Civil Code is fulfilled), state administratuve law and law No. 2/2014 (if Article 16 paragraph 1. Letter d of law No. 12/2014 on Notarial Position is fulfilled). The Judge of the Supreme Court hands down the Ruling No. 2468 K/Pid/2006 which states that the Court rejects the cassation appeal of the appelant, the prosecuting attorney or public prosecutor in the District Attorney’s Office or the Provincial General Attorney’s Office of Surabaya because the judge has his opinion that the case of witnesses in the Notarial Deed is nit the case material.Keyword : Notary, Deed Minute, Deed Copy, Liability
ANALISIS TERHADAP PERJANJIAN KREDIT PADA KOPERASI SIMPAN PINJAM
Authors: Rusli Tami , Seftiniara Intan Nurina , Herindria Andreas
Published: September 2023

The agreement is a legal relationship between one legal subject and another legal subject in the field of assets, where one legal subject is entitled to achievements and so are other legal subjects who are obliged to carry out their achievements in accordance with the agreement. The presence of credit union as an effort to realize the welfare of members and the community should be able to trigger and expand businesses for the community to carry out productive, innovative, and effective activities so that the community gets the maximum benefit and welfare. In a credit union, each member is an owner, and not just a member. Serving members based on credit union principles so that members are independent, loyal friends, and prosperous, for this we need mutual trust, mutual strengthening, mutual benefit, and fully aware that every member of a savings and loan credit union is a member and owner.
TRANSFORMASI BADAN USAHA MILIK NEGARA SEBAGAI OBYEK HUKUM DAGANG INTERNASIONAL DALAM PARADIGMA GLOBALISASI EKONOMI
Authors: Zaelani Muhammad Aziz , Dewi Nourma , Nurwanti Yulian Dwi
Published: September 2023

This article answers the problem of the influence of economic globalization on BUMN (State-Owned Enterprises/SOE) and the position of BUMN as an object of International Commercial Law in the paradigm of economic globalization. BUMN, in its development, is required to fulfill two main functions, namely public service and profit-oriented. In the dynamics of economic globalization, the global economic association also has a significant impact on countries to adapt. One way is to maximize the role of public companies. The expansion of the functions of BUMN, followed by physical and managerial modernization, is a challenge to maintain the function of BUMN as an extension of the state in realizing people's welfare. Articles examine laws and regulations, legal principles, literature, and doctrine related to the issues presented, thus including doctrinal legal research. The results of the study show that the influence of economic globalization on BUMN has expanded the functions of BUMN, public services, and seeking profit. Meanwhile, the position of BUMN as an object of international trade law in the paradigm of economic globalization includes the competitive model, the coordinative model, and the coordinative hegemony model.
OFFSHORE OIL SPILL AS LIABLE MARINE POLLUTION BY INTERNATIONAL LAW OF THE SEA
Authors: Lumentah Marco Bastian , Amalia Ayu Riska , Taufik Zahratul'ain , Nirmala Atika Zahra , Rahmania Nunung
Published: September 2023

Notwithstanding the case for the oil spill, international laws of the Sea regarding marine pollution are a few environmental regulations that the UNCLOS and other treaties mandated to countries, companies, and individuals. In this paper, the analysis will be on the case of the Montara Oil Spill, how it is regulated in the common practice of public international law, and how the case was undertaken ever since the spillage occurred. The result would imply how the case can be further rationalized and resolved in hopes of better describing how such liabilities come into play. Also, however, Australia has done her responsibility independently. Therefore, this paper's arguments and claims were constructed through secondary sources such as reports and legal approaches through appropriate regulations concerning the subject matter.
STEGANOGRAPHY CAPACITY ANALYSIS OF TEXT IN TEXT WITH SENTENCE STRUCTURE IN INDONESIAN
Authors: Siahaan R. Fanry , Sitohang Amran , Febrian Ibnu , Putri Widia
Published: September 2023

Data security issues become very important when the computer has been used as a communication tool on a global network (internet). One method that is quite popular for securing data from irresponsible parties is text-based steganography, where confidential data or information is hidden or inserted into other text media so as not to arouse suspicion from other parties. Based on the input data calculated on the number of words, it has a significant influence on the results of the stegotext. This can be seen from the comparison of the length of the input message which is calculated in the number of words with the length of the output message (stegoteks) which is influenced by the length of the style (pattern) of the sentence structure used. For input data with a word length of 1, the average capacity of the stegotext is 8 to 9 words or 12.4%, for input word length 2, the average capacity of the stegotext is 22 words or 8.85% and the input word length is 4 then the capacity of the stegotext is between 30 to 33 words or equivalent to 12.91%.
Keywords :Text Steganography; Sentence Pattern; Payload Balancing Capacity
Analysis of Application of Fuzzy Grid Partition on Mamdani Method Fuzzy Inference System
Authors: Marbun Murni , - Sandhuri , - Aishwarya
Published: September 2023

The Mamdani method has been widely used for various control devices, which is the beginning of fuzzy technology and has the advantage of being able to express concepts that are difficult to formulate and the use of fuzzy membership functions in making objective observations of subjective values, making it easier to make decisions that are full of uncertainty. The Mamdani method has also been widely used for various optimization problems. This study produces new findings on the analysis of the application of fuzzy grid partition on the fuzzy inference system of the Mamdani method for the issue of optimizing the amount of production of a food product. The research stage begins with determining the number of partitions that will form a grid structure. The grid formed from the combination of relations between each partition will have the potential to develop rules. Based on the results of the analysis, determining the amount of production using the Mamdani method produces a smaller amount of production but produces stock output that is not within the specified stock limit, while the application of fuzzy grid partition in the Mamdani method has a higher and correct amount of product because it produces stock output that is at the specified stock limit
USE OF DATA AUGMENTATION AND EXPLORATORY DATA ANALYSIS IN ENHANCING IMAGE FEATURES ON APPLE LEAF DISEASE DATASET
Authors: Rifaldo Rifaldo , Sitompul Daniel Ryan Hamonangan , Sinurat Stiven Hamonangan , Situmorang Andreas , Rahmad Julfikar , Ziegel Dennis Jusuf , Indra Evta
Published: September 2023

Apples are an essential commodity produced in Batu City, Malang. In 2017, Batu City, Malang, produced 19.1 tons of apples, while in 2018, Batu City, Malang, produced 15.9 tons of apples. It can be concluded that the decline in the number of apple harvests in Batu City, Malang. With the influence of technology in agriculture, the influence of technology can be used to detect diseases on leaves to overcome the decrease in the number of harvests. With the Image Augmentation method used in this study, the existing dataset can have 6x more features. So that the healthy category, which previously had 516 image features, now has 3096 image features, the scab category, which previously had 592 image features, now has 3552 image features and the rust category, which previously had 622 image features, now has 3732 image features. With a dataset with 3000 image features, the model to be made can have a higher accuracy value. The model can be said to be sturdy/sturdy/good, or the model to be made can carry out the classification process with a good level of accuracy.
ANALYSIS OF STUDENT SATISFACTION WITH STUDENT MANAGEMENT SERVICES IN THE INFORMATION SYSTEMS STUDY PROGRAM AT PRIMA INDONESIA UNIVERSITY USING THE SERVICE QUALITY (SERVQUAL) METHOD
Authors: Wijaya Malvin Luckianto , Sitompul Daniel Ryan Hamonangan , Sinurat Stiven Hamonangan , Rahmad Julfikar , Fahmi Mohammad Irfan , Indra Evta
Published: September 2023

The purpose of this research is to analyze the level of student satisfaction with student management services in the Information Systems Study Program at Prima Indonesia University. The method used in this study is the Service Quality method to measure the level of student satisfaction. The results of the research show that the level of student satisfaction with student management services is 4.28 and the Servqual method has good quality in measuring student satisfaction.
IMPLEMENTATION OF DESIGN THINKING METHODS IN UI/UX DESIGNING JOB SEARCHING APPLICATIONS
Authors: Sriardi Mohammad Didit , - Tukino , Nurapriani Fitria
Published: September 2023

Major changes in the job search have occurred with the development of the digital age. Therefore, user experience enhancement (UserExperience, UX) and user interface (UserInterface, UI) in job search applications is becoming an urgent need. This study aims to explore the application of the methoddesign thinkingin designing the UI/UX of a job search application namedCareer Hunt.Design thinking, a user-centric approach, enabling developers to understand deeply the needs, challenges and expectations of users, and create innovative and effective solutions. There are five stages used in this study: empathy, definition, ideation,prototype, and testing / test. In this study, interviews and contextual observations were conducted to gain a deeper understanding of user behavior and needs. Based on these findings, the main issues need to be solved, and then facilitate the sessionbrainstormingto generate a variety of potential solutions. Then, developprototypebased on those ideas and do user testing.feedbackreceived is used for literacy and further improvement. As a result, useDesign Thinkingin designUI/UXThis job search application has succeeded in increasing user satisfaction levels as well as job search efficiency.
 
Keywords:Job Search,Career Hunt, Design Thinking, UI/UX
ANALYSIS OF CUSTOMER SATISFACTION INDEX METHOD ON THE PERCEPTION OF UNIVERSITAS PRIMA INDONESIA'S NEW BUILDING BY ITS STUDENTS
Authors: Nasution Donni , Sinaga Aldi Hermanto , Samudera Indra , Hulu Iman Paskalis
Published: September 2023

The rapid growth of private universities and higher education institutions has led to increased competition among faculties to meet their set quotas, resulting in uneven student distribution. Universities and faculties must consistently strive to improve quality in various areas to achieve their set quotas. In measuring student satisfaction, a questionnaire was distributed to students. Out of the 369 questionnaires filled out, only 235 were deemed valid and analyzed. The analysis was conducted using two calculation methods, the first being the Customer Satisfaction Index (IPA), which resulted in a 75.42% satisfaction rate, and the Importance Performance Analysis (IPA), which identified 10 indicators in quadrant 1. It can be said that both methods resulted in a fairly satisfactory service quality.
IMPLEMENTATION OF DATA MINING TO PREDICT THE VALUE OF INDONESIAN OIL AND NON-OIL AND GAS IMPORT EXPORTS USING THE LINEAR REGRESSION METHOD
Authors: Ompusunggu Elvis Sastra , Sinaga Wilson , Siahaan Mikael , Winata Jaspin
Published: September 2023

Indonesia's export-import activities in recent years, the value of Indonesia's exports and imports has decreased due to global conditions. The problems that occur are the uncertainty and complexity in estimating the value of international trade in the oil and gas and non-oil and gas sectors, dependence on just one or a few markets, and the problem of unfair competition, unfair competition between business actors can reduce export-import prices. The value of oil and gas and non-oil and gas exports and imports is influenced by several external factors that are difficult to predict, such as fluctuations in oil and gas prices, changes in trade policies, and global economic factors. The prediction results are obtained every month from the export value data using the rapid miner application. From the export data, the value of non-oil and gas exports obtains a very high value compared to the export data of oil and gas values. Then the results from rapid miner using the linear regression algorithm are obtained. The predicted import value of oil and gas and non-oil and gas value data in June is 209,162,268, and the predicted export value of oil and gas and non-oil and gas value data in June is 349,285,781 and non-oil and gas which more are predicted to have the highest value compared to the value of oil and gas in each month.
COMPARATIVE ANALYSIS OF STROKE CLASSIFICATION USING THE K-NEAREST NEIGHBOR DECISION TREE, AND MULTILAYER PERCEPTRON METHODS
Authors: Barus Ertina Sabarita , Halim Jenny Evans , Yessica Sally
Published: September 2023

Stroke has become a serious health problem; the main cause of stroke is usually a blood clot in the arteries that supply blood to the brain. Strokes can also be caused by bleeding when blood vessels burst and blood leaks into the brain. In one year, about 12.2 million people will have their first stroke, and 6.5 million people will die from a stroke. More than 110 million people worldwide have had a stroke. Handling that is done quickly can minimize the level of brain damage and the potential adverse effects. Therefore, it is very important to predict whether a patient has the potential to experience a stroke. The K-Nearest Neighbor, Decision Tree, and Multilayer Perceptron algorithms are applied as a classification method to identify symptoms in patients and achieve an optimal accuracy level. The results of making the three algorithms are quite good, where K-Nearest Neighbor (K-NN) has an accuracy value of 93.84%, Decision Tree is 93.97%, and Multilayer Perceptron (MLP) is 93.91%. The best accuracy value is the Decision Tree algorithm with an accuracy difference of no more than 0.10% with the two algorithms used.
FACTORS OF POVERTY OF THE WORKING POPULATION AND WAYS TO REDUCE IT
Authors:   Financial University under the Government of the Russian Federation Moscow, Russia, Safonov A.L. , Dolzhenkova Yu.V. ,   Financial University under the Government of the Russian Federation Moscow, Russia, Veshkurova A.B. ,   Financial University under the Government of the Russian Federation Moscow, Russia
Published: September 2023

The aim of the study is to identify the reasons for the emergence of the "working poor", as well as the consequences of this type of poverty for society, and to propose possible ways to solve this problem. The task is to identify and assess the factors, causes, and trends of economic poverty in Russia, and propose measures to reduce it. The relevance of the work is that the poverty of people who, even having a job, cannot provide themselves and their families with an acceptable standard of living due to low wages, underemployment, insufficient social protection and other factors, remains one of the main social problems in many countries. The research methods are analysis and synthesis of scientific literature, the Federal State Statistics Service (Rosstat) statistical data, and materials of the Sample Survey of Household Budgets (SSHB). The result of the study is scientifically based proposals for reducing economic poverty. It is concluded that the problem of poverty among the working population requires a comprehensive approach, including political and economic measures aimed at increasing economic mobility, timely indexation of the minimum wage, training, and retraining.
Critérios de diagnóstico de Morte Encefálica: a experiência de médicos com o atual protocolo
Authors: Fonseca Macedo Letícia , Da Rocha Bastos Thalita , Brito da Silva Yasmim Carmine , Souza Cabeça Hideraldo Luis , Vidigal Soeiro Ana Cristina
Published: September 2023

Introdução. A morte encefálica (ME) é definida pela perda completa e irreversível das funções cerebrais e de tronco cerebral. Seu diagnóstico segue critérios clínicos específicos, o que requer conhecimento e habilidades médicas. Objetivo. Verificar o conhecimento e a experiência dos médicos acerca do atual protocolo de diagnóstico de ME. Método. Estudo quantitativo, exploratório, descritivo e transversal, com participação de 99 médicos de um hospital de referência em atendimento ao trauma, da região metropolitana de Belém. A coleta de dados ocorreu entre outubro de 2021 a junho de 2022. Foi aplicado um questionário elaborado pelos autores contendo perguntas sobre o conhecimento e a experiência com o protocolo de ME. Resultados. 60,6% dos participantes eram do sexo masculino, com idade entre 20 e 39 anos (75,8%) e graduação entre 2011 a 2020 (50,5%). Considerando as especialidades, houve melhor desempenho entre os participantes que eram médicos neurocirurgiões (p=0,003). Também houve maior número de acertos nos seguintes grupos: médicos que foram responsáveis pela abertura de protocolo de ME (p<0,001), os que possuíam experiência anterior no atendimento a pacientes em coma (p=0,003), aqueles que haviam participado de treinamento/capacitação (p<0,001). Ainda, 39,4% dos médicos relataram se sentir desconfortáveis ao ter que comunicar o diagnóstico aos familiares. Quanto à introdução do tema na graduação, 28,3% relataram como ruim. Conclusão. Os achados revelaram que há lacunas no conhecimento sobre o atual protocolo de ME, particularmente durante a formação acadêmica, sendo necessário uma maior discussão sobre o tema ainda na graduação.
Aux origines de l’humanité : retracer les grandes étapes de notre évolution biologique et culturelle à partir de l’étude du cerveau de nos ancêtres
Authors: Beaudet Amélie , Fonta Caroline
Published: September 2023

Human Origins : Tracking the Human Biological and Cultural Evolution from the Study of the Brain of our Ancestors. Who were the hominins associated to the oldest tools that were found in East Africa ? If the lithic artefacts could be mute on these aspects of our history, the field of (paleo) neurology may contribute to the ongoing debates on the identity of the first toolmakers and the assessment of their cognitive capacities. In this paper, we provide a brief synthesis of what we know about the cerebral condition of Australopithecus, Paranthropus and early Homo, which are the potential earliest tool makers. We also demonstrate how, from the study of fossil remains of our ancestors and the use of imaging and 3D modelling techniques, we can reconstruct the evolutionary history of the brain of our ancestors and their behaviours. In particular, we insist on the interest of developing a multidisciplinary approach combining experiments (e. g., replicating the processes involved in toolmaking), imaging (e. g., functional MRIs, microtomography), paleoanthropology (e. g., identifying fossil remains) and statistics (e. g., shape analyses) for addressing these questions.