bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness, Adverse Events, and Immune Response Following Double Vaccination with BNT162b2 in Staff at the National Comprehensive Cancer Center (NCCC)
Authors: Palacka Patrik , Pol’anová Monika , Svobodová Alena , Žigmond Jan , Zanchetta Katarína , Gombárová Vlasta , Vulganová Martina , Slopovský Ján , Obertová Jana , Drgoňa Ľuboš , Mego Michal , Pechan Juraj
Published: April 2022

Vaccination remains the leading strategy against COVID-19 worldwide. BNT162b2 is among the first licensed vaccines with high effectiveness. However, the role of antibody and cell immunity response monitoring after vaccination remains unclear. We conducted a 6-month prospective study involving the employees of NCCC in Slovakia, who were tested for IgG antibody and cell immune responses after double vaccination with BNT162b2. IgG antibodies were detected at 3, 7, and 26 weeks, respectively. At 6 months, blood samples were tested by two different interferon-γ release assays to determine responses to spike protein antigen and nucleocapsid protein antigen of the novel coronavirus. Results were stratified by gender and body mass index (BMI). Statistical significance was set at p = 0.05. The medical records of 94 respondents (71 females) were analyzed. The mean age was 40.2 years and the mean BMI was 26.4 kg/m2. At 6 months after double vaccination, effectiveness was 97.9%. The side effects of the BNT162b2 vaccine were similar after both doses, with no serious adverse events or new safety signals recorded. The IgG index declined rapidly (p < 0.0001), and 42.6% of subjects had positive and 57.4% borderline or negative immune cell response at 6 months (p < 0.0001). Both T cell activation and IgG counts were lower in morbidly obese patients when compared to some other BMI categories. This study confirmed an acceptable toxicity profile and the high efficacy of BNT162b2 despite a rapid decline of IgG level and negative cell-mediated immunity response in most subjects. An individualized approach to vaccination could be considered in morbidly obese individuals.
Phenotypic and Genotypic Characterization of C. perfringens Isolates from Dairy Cows with a Pathological Puerperium
Authors: Kronfeld Hanna , Kemper Nicole , Hölzel Christina S.
Published: April 2022

Clostridium perfringens (C. perfringens) forms part of the intestinal microbiome, but is also a known pathogen in histotoxic infections. The significance of the pathogen as a cause of uterine infections in cattle has been little studied so far. Here, we analyzed the association between a pathological puerperium in cattle and the detection of C. perfringens in a prospective longitudinal study. Clostridium perfringens were only found in vaginal and uterine samples of diseased cattle, and were absent in healthy controls. Isolates (n = 21) were tested for the production of major toxins (alpha-, beta-, epsilon-toxin) by ELISA and for the potential of production of major (alpha-, beta-, iota-toxin) and minor toxins (beta2 toxin) by PCR. Furthermore, antimicrobial susceptibility was also tested phenotypically by microdilution. Despite the frequent use of tetracycline treatment in cows suffering from puerperal disorders, no isolate showed phenotypic tetracycline resistance. Most isolates did not release major amounts of toxin. The strict association of C. perfringens with puerperal disease, together with the absence of major toxins might hint towards a major role of other or unknown clostridial virulence factors in uterine disease.
Benefits, Inconveniences, and Facilities of the Application of Rain Gardens in Urban Spaces from the Perspective of Climate Change—A Review
Authors: Bąk Joanna , Barjenbruch Matthias
Published: April 2022

The need to support existing sewage systems is obvious due to the noticeable consequences of climate change, such as extreme rainfall, which is causing more urban flooding. It is believed that these phenomena will intensify in the long-term, and that sewage systems will be overloaded with stormwater. Consequently, cities will need more opportunities to protect themselves from flooding. Moreover, longer periods of drought will increase the temperatures in towns. The use of blue and green infrastructure is being used to adapt to climate change and to limit its effects in cities. However, it is important not to apply these solutions indiscriminately. They have obvious advantages, but are also limited in their uses. Facilities are also being developed for the design and construction of green infrastructure. This article presents the benefits of using rain gardens in urban spaces and in relation to other forms of blue–green infrastructure; it also explored the problems that may occur while using them. More important facilitations in the implementation of rain gardens into urban fabrics are discussed, particularly in the context of the existing inconveniences. A holistic approach to the issue was applied addressing technical, economic, environmental, and social aspects.
Robust Magnetic γ-Fe2O3/Al–ZnO Adsorbent for Chlorpyriphos Removal in Water
Authors: Boulares Miryam , Chamam Baha , Mejri Amal , Wahab Mohamed Ali , Haddouk Amani , El Mir Lassaad , Hamzaoui Ahmed Hichem , Kallel Amjad , Tizaoui Chedly , Trabelsi Ismail
Published: April 2022

In this research, the removal of the pesticide chlorpyriphos (CPE) from water by adsorption using a novel adsorbent made of γ-Fe2O3/Al-ZnO nanocomposite was studied. The adsorbent was characterized using Fourier-transformed infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) surface area, and vibrating sample magnetometry (VSM). The main parameters affecting the adsorption process, including the initial pH (2–12), the concentration of pesticide (10–70 ppm), the %Fe2O3 of the adsorbent, and the adsorption time (≤60 min), were studied. The results demonstrated that the adsorption of CPE depended on the pH, with a maximum removal of 92.3% achieved at around neutral pH. The adsorption isotherm was modelled and the results showed that the Freundlich model fitted the experimental data better than the Langmuir and Temkin models. The kinetics of adsorption were also studied and modelled using the pseudo-first-order and pseudo-second-order models, with the former being found more suitable. Energy dispersive X-ray (EDX) analysis confirmed the adsorption of CPE on γ-Fe2O3/Al-ZnO, while FTIR analysis suggested that the hydroxyl, N-pyridine, and chloro functional groups governed the adsorption mechanism. Furthermore, VSM analysis revealed that the magnetization saturation of γ-Fe2O3/Al-ZnO nanocomposite, after CPE adsorption, was slightly lower than that of fresh γ-Fe2O3/Al-ZnO but remained adequate for the efficient separation of the adsorbent simply using a magnet. This study demonstrates that binary γ-Fe2O3/Al-ZnO magnetic nanocomposites are effective for the removal of chlorpyriphos and could be highly promising materials for the removal of emerging pollutants in wastewater.
Clinician views on optimism and empathy in primary care consultations: a qualitative interview study
Authors: Hughes Stephanie , Vennik Jane Louise , Smith Kirsten A , Bostock Jennifer , Howick Jeremy , Mallen Christian , Little Paul , Ratnapalan Mohana , Lyness Emily , Leydon Geraldine M , Dambha-Miller Hajira , Morrison Leanne , Everitt Hazel A , Bishop Felicity L
Published: April 2022

Background

Practitioner expressions of optimism and empathy may improve treatment engagement, adherence, and patient satisfaction but are not delivered consistently amid the challenges of everyday clinical practice.

Aim

To explore primary care practitioner (PCP) views about optimistic and empathic communication in consultations; and to identify behavioural, attitudinal, and/or contextual issues likely to encourage or deter PCPs from practising such communication.

Design & setting

Qualitative interview study with 20 PCPs (GPs, practice nurses, and primary care physiotherapists).

Method

Semi-structured telephone interviews with 20 PCPs. Data were analysed thematically.

Results

A conceptual mismatch between optimism and patient expectations became apparent; when asked how PCPs communicate about the likely effects of a treatment, answers were focussed around managing patient expectations. When prompted, it became clear PCPs were open to communicating optimistically with patients, but emphasised the need for realism. Concerns arose that patients may not be receptive to optimistic messages, especially when holding negative expectations. PCPs felt that expressing empathy is fundamental to all clinical consultations, noting that it can be challenging. Some PCPs worried that increasing expressions of empathy might increase their risk of clinician burnout and felt guilty about (appropriately) communicating empathy while maintaining some emotional distance.

Conclusion

PCPs agreed expressing realistic optimism during consultations could aid communication and would constitute a novel change to practice. PCPs strive for clinical empathy but can struggle to manage emotional self-protection. Specific training to help PCPs express realistic optimism and empathy, and better utilise efficient non-verbal skills could help these issues.
Tingkat Kesiapan Venue MICE Di Era New Normal COVID-19 (Stusi Kasus DKI Jakarta)
Authors: ERFINDA YOSI , NOOR FALAH ZETA
Published: April 2022

Coronavirus disease (COVID-19) is an infectious disease caused by SARS-CoV-2 Virus. In Beginning of 2020, World Health Organization has declared as Pandemic all around the world. It has paralysed economic activities which include Meeting, Incentive, Convention and Exhibition and forced all governments in the world, including Indonesia set a policy of controlling and preventing COVID-19.This policy force of the activity New Normal in Indonesia. Based on statement by Ministry of Tourism and Economic Creative in 2020 there some 84,8% MICE activities in Indonesia was cancelled. Ministry of tourism and economic creative made policy for reduce impact of pandemic through Cleanliness, Health, Safety and Environmental Sustainability for MICE. DKI Jakarta is  the object of this research. The researcher can collected 38 respondens of Venue in DKI Jakarta such as Hotel, Convention Center, Resort and Apartement used online survey. Research Methodology use GAP Analysis to compare between the application of health protocol that done by Venue MICE or against a standard applied in guidance of CHSE for MICE in Indonesia. There are 8(eight) criteria in guidance of CHSE for MICE. The research result showed that 1(one) criteria is food and beverages providers fulfilled the achievements 100% . And for 7(seven) criteria in positions of 75% - < 100% it means the current of Venue MICE in the standard assessment result with the standard applied in guidance CHSE is will fulfilled. This should  served as reference Venue MICE in DKI Jakarta can organize MICE activities in Era of New Normal.
Pengaruh Tegangan Uji Terhadap Nilai Resistansi Dari Resistor Standar Dalam Order Giga Ohm
Authors: Khairiyati Lukluk , Azzumar Muhammad , Fitrah Yayienda Nibras
Published: April 2022

Dalam rangka mendukung sistem pengukuran arus rendah untuk rentang nA diperlukan karateristik resistor standar tinggi dalam untuk nominal  1 GΩ, 10 GΩ dan 100 GΩ  dengan variasi tegangan uji yang  telah dilakukan pengukurnya. Tujuannya adalah untuk mengetahui pengaruh tegangan uji terhadap nilai resistansi dari resistor standar  1 GΩ, 10 GΩ dan 100 GΩ. Selain itu, hal tersebut dapat bermanfaat juga untuk mengetahui koreksi nilai resistansi saat tegangan uji yang disuplai tidak sesuai dengan tegangan kerja optimumnya. Pengukuran dilakukan dengan menurunkan nilai resistor standar  1 GΩ, 10 GΩ dan 100 GΩ dengan menggunakan metode langsung dan Teraohmmeter sebagai standar acuan yang mimiliki kemampuan tegangan ujinya 1V sampai 1000 V. Perubahan nilai resistansi terhadap perubahan arus uji memberikan fenomena bahwa nilai resistansi berubah secara kuadratik. Persamaan kuadratik yang diperoleh adalah y = 4E-10x2 - 5E-07x + 1,0003 MΩ, y = 6E-09x2 - 8E-06x + 10,007  MΩ  dan y = 3E-07x2 - 0,0005x + 100,11 dengan ketidakpastian baku 0,0045 ppm, 1,2 ppm dan 449 ppm.
Pemanfaatan Jeruk Nipis (Citrus Aurantifolia) Pada Pebuatan Virgin Coconut Oil (VCO) Dari Santan Kelapa
Authors: Yuniwati Murni , Kusmartono Bambang , Andaka Ganjar , Nanda Rama Nitia
Published: April 2022

Pembuatan (Virgin Coconut Oil) VCO dapat dilakukan dengan cara pengasaman, yaitu dengan cara ditambahkan asam agar diperoleh pH tertentu  yang memungkinkan tumbuhnya bakteri pengurai protein dalam santan kelapa sehingga terbentuk VCO. Jeruk nipis banyak mengadung asam alami memiliki aroma yang khas dan banyak mengandung zat zat bermanfaat  dan memungkinkan untuk membuat suasana asam dalam pembuatan VCO.

Kecepatan pembentukan VCO sangat menentukan kuantitas dan kualitas VCO. Dengan kecepatan yang besar maka waktu untuk menghasilkan VCO lebih singkat, hal ini akan menghindarkan dari kemungkinan reaksi samping atau proses pembusukan yang akan menurunkan kualitas VCO. Beberapa faktor yang menyebabkan kecepatan pembentukan VCO antara lain yang akan dipelajari dalam penelitian ini adalah suhu ruangan dan jumlah jeruk nipis yang ditambahkan ke dalam santan kelapa. 

Dalam penelitian ini akan dipelajari proses pembentukan VCO dari santan kelapa, dengan pengasaman menggunakan jeruk nipis. Santan kelapa didiamkan 30 menit untuk memisahkan skim dan airnya. Skim yang diperoleh ditempatkan dalam wadah ditambahkan air jeruk nipis dengan volume tertentu, wadah ditempatkan dalam ruangan dengan suhu tertentu didiamkan agar terjadi proses fermentasi dalam selang waktu tertentu, VCO yang terbentuk diukur volumenya kemudian dianalisis sifat fisis maupun sifat kimianya.

Berdasarkan hasil penelitian ini, hasil terbaik dieroleh dengan menggunakan penambahan jeruk nipis 5% volume dan dilakukan pada suhu 38 oC, dengan kondisi tersebut proses pembuatan VCO memerlukan waktu 4 jam, dengan menggunakan 800 ml skim dari 1kg kelapa  di diperoleh hasil VCO yang  jernih sebanyak 220 ml dengan densitas 0,91 gr/mL.
Power Dynamics Among Health Professionals in Nigeria: A Case Study of the Global Fund Policy Process
Authors: Lassa Samuel , Saddiq Muhammed , Owen Jenny , Burton Christopher , Balen Julie
Published: April 2022

Background: Health workers are central to health policy-making. Given health systems’ complex, dynamic and political nature, various forms of ‘hidden power’ are at play as health workers navigate health systems. This study aims to explore the dynamics of power and its sources, and how this shapes policy-making and implementation within the Nigerian health systems context. Methods: The case study was the Global Fund grant in Nigeria, and results are based on an in-depth qualitative study involving 34 semi-structured key informant interviews (KIIs), board-meeting observations, and documentary analysis conducted in 2014 and 2016. Participants held mid to senior-level positions (eg, Director, Programme Manager) within organisations involved with Global Fund activities, particularly proposal development and implementation. Data were analysed using thematic analysis in order to gain insight into the power dynamics of health professionals in policy processes. Results: Medical professionals maintained dominance and professional monopoly, thereby controlling policy spaces. The structural and productive power of the biomedical discourse in policy-making encourages global actors and the local government’s preference for rapid biomedical models that focus on medications, test kits, and the supply of health services, while neglecting aspects that would help us better understand the poor uptake of these services by those in need. The voices of the repressed groups (eg, non-clinical experts, patients and community based organisations) that better understand barriers to uptake of services are relegated. Conclusion: Professional monopoly theories help illustrate how medical professionals occupy and maintain an elite position in the health system of Nigeria. Structural and agential factors specific to the contexts are key in maintaining this professional monopoly while limiting the opportunities for other health occupations’ rise up the social status ladder.
Community Participation in Primary Healthcare in the South Sudan Boma Health Initiative: A Document Analysis
Authors: Belaid Loubna , Sarmiento Iván , Dimiti Alexander , Andersson Neil
Published: April 2022

Background: Community participation is central to primary healthcare, yet there is little evidence of how this works in conflict settings. In 2016, South Sudan’s Ministry of Health launched the Boma Health Initiative (BHI) to improve primary care services through community participation. Methods: We conducted a document analysis to examine how well the BHI policy addressed community participation in its policy formulation. We reviewed other policy documents and published literature to provide background context and supplementary data. We used a deductive thematic analysis that followed Rifkin and colleagues’ community participation framework to assess the BHI policy. Results: The BHI planners included inputs from communities without details on how the needs assessment was conducted at the community level, what needs were considered, and from which community. The intended role of communities was to implement the policy under local leadership. There was no information on how the Initiative might strengthen or expand local women’s leadership. Official documents did not contemplate local power relations or address gender imbalance. The policy approached households as consumers of health services. Conclusion: Although the BHI advocated community participation to generate awareness, increase acceptability, access to services and ownership, the policy document did not include community participation during policy cycle.
How and Why Context Matters: A Personal Reflection Comment on "Stakeholder Perspectives of Attributes and Features of Context Relevant to Knowledge Translation in Health Settings: A Multi-Country Analysis"
Authors: Kitson Alison
Published: April 2022

This commentary acknowledges that the evidence-based practice (EBP) movement did not automatically or initially understand the impact of context on successful implementation (SI). The subsequent work of research teams, such as the PARIHS (Promoting Action on Research in Health Services) team, and the Ottawa team led by Squires, have contributed to the ongoing refinement of the concept. However, still under discussion is whether having a more comprehensive set of contextual attributes will necessarily lead to more implementation success. Just as the strength of the evidence does not automatically lead to implementation success, so having a comprehensive understanding of contextual factors will not necessarily improve implementation uptake.
IGF-I combined with exercise improve diabetes-induced vascular dysfunction in heart of male Wistar rats
Authors: Niknam Zahra , Samadi Mahrokh , Ghalibafsabbaghi Ataollah , Chodari leila
Published: April 2022

Introduction: This research investigates the impact of insulin-like growth factor-I (IGF -I)and exercise on mediators associated with angiogenesis (VEGF-A, TSP-1, and NF-кβ) and capillarization status of the diabetic rats’ hearts. Methods: Splitting of forty Wistar male rats into five groups occurred as following: control,diabetes, diabetes+IGF-I, diabetes+exercise, and diabetes+exercise+IGF-I.Through intraperitoneal administration of 60 mg/kg streptozotocin, the condition of Type 1diabetes was escalated. After four weeks of treatment with IGF-I (2 mg/kg/day) or treadmill exercise (17 m/min, zero degrees slope, 30 min/day), in the heart, microvascular density and protein levels of VEGF-A, TSP-1, and NF-кβ were determined by H & E staining and ELISA,respectively. Results: Within the diabetic group, observations present a significant decrease in VEGF-A and MVD levels, whereas an increase in the TSP-1 and NF-Κb levels. While these impacts were reversed by either IGF-I or exercise treatments, simultaneous treatment had synergistic effects. Moreover, among diabetic rats, undesirable histologic alterations of the heart were demonstrated, including myonecrosis, interstitial edema, hemorrhage, and mononuclear immune cell infiltration, whereas treatments improved these changes. Conclusion: These data manifest that IGF-I and exercise can increase the cardiac angiogenesis of diabetic rats through increasing expression of VEGF-A, and decreasing TSP-1 and NF-кβproteins level, also can improve myocardial tissue damages.
Effect of hyperglycemia treatment on complications rate after pediatric cardiac surgery
Authors: Naghipour Bahman , Bagerpour Mahdieh , Shadvar Kamran , Golzari Samad E.J. , Faridaalaee Gholamreza
Published: April 2022

Introduction: The goal of this study was to elucidate harmful complications of intraoperative hyperglycemia following children cardiac surgery and benefits of insulin administration for accurate blood sugar controlling. Methods: this study is a Randomized clinical trial. We conducted this study in the operating room of shahid madani hospital. Fifty patients who were children under 12 years old undergone cardiac surgery using cardiopulmonary bypass (CPB). Intraoperative insulin infusion was administered intravenously targeting blood sugar levels of 110-140 mg/dL. Blood sugar and arterial blood gas (ABG) were measured every 30 min during operation. Results: Inotropes were used less in the study than the placebo group during surgery. The means of hospitalization and extubation time were more in the placebo group than the study group(P=0.03) and (P=0.005), respectively. However, the mean time of hospitalization in the ICU ward did not differ significantly between the two groups. Conclusion: Hyperglycemia has a relation with long time of intubation and hospitalization in ICU. These findings suggest the positive effect of accurate blood sugar control on reducing complication and hospitalization time in children undergoing cardiac surgery.
The fate of the fresh autologous pericardium after right ventricular outflow tract reconstruction
Authors: Tatari Hassan , Omrani Gholamreza , Arabian Maedeh , Mozaffari Kambiz , Toloueitabar Yaser , Asadian Sanaz , Givtaj Nader , Gholampour Dehaki Maziar , Jalali Amirhosein
Published: April 2022

Introduction: The autologous pericardium, treated or fresh, is used in reconstructive cardiovascular surgery. We aimed to describe the features of fresh pericardium utilized in right ventricular outflow tract (RVOT) reconstruction, years after the initial surgery. Methods: This cross-sectional study was performed on 72 patients (65.3% male, mean age =18.68 ± 9.63 y) with a history of RVOT reconstruction with the fresh autologous pericardium who underwent reoperation. During the surgery, a 1 × 1 cm sample was cut from the previous pericardial patch, and hematoxylin and eosin (H & E), Masson’s trichrome, and immunohistochemistry (IHC) staining was conducted. All the stained slides were evaluated,and the descriptive results were explained. Results: The mean follow-up duration was 13.48 ± 7.38 years. In preoperative evaluations,53 (73.6%) patients exhibited no RVOT dilatation, 17 (23.6%) showed mild RVOT dilatation,and 2 (2.8%) had RVOT aneurysms. The H & E staining revealed no calcification in 80.55%(58/72), mild calcification in 9.72% (7/72), and moderate calcification in 9.72% (7/72) of the total samples. None of the specimens demonstrated a marked calcification. All the samples were positive for CD31, CD34, smooth muscle alpha-actin, and von Willebrand factor in IHC. In Masson’s trichrome staining, on average, 64.74% (±18.61) of the tissue sections contained collagen fibers. Conclusion: The fresh autologous pericardium, utilized for RVOT reconstruction, showed viability, growth potential, positivity for endothelial cell markers, vascular differentiation,insignificant calcification, and no stenosis at long-term follow-up. We would, therefore, suggest it as a suitable choice for such reconstructive operations. Moreover, its usage during total correction of tetralogy of Fallot could be safe, feasible, and durable.
Prognostic significance of CHADS2 and CHA2DS2-VASc scores to predict unfavorable outcomes in hospitalized patients with COVID-19
Authors: Montazeri Mahnaz , Keykhaei Mohammad , Rashedi Sina , Karbalai Saleh Shahrokh , Pazoki Marzieh , Hadadi Azar , Sharifnia Seyyed Hamidreza , Sotoodehnia Mehran , Ajloo Sanaz , Kafan Samira , Ashraf Haleh
Published: April 2022

Introduction: Owing to the imposed burden of the coronavirus disease 2019 (COVID-19),the need for stratifying the prognosis of patients has never been timelier. Hence, we aimed to ascertain the value of CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-M (one point for male instead of female) scores to predict unfavorable outcomes in COVID-19 patients. Methods: We enrolled consecutive patients above 18 years of age with confirmed COVID-19,who were admitted between February 16 and November 1, 2020. The primary endpoint of this study was three-month all-cause mortality. The secondary endpoints were considered four major in-hospital clinical features, including acute respiratory distress syndrome, cardiac injury,acute kidney injury, and mechanical ventilation. Results: A total of 1,406 hospitalized COVID-19 patients were studied, among which 301(21.40%) patients died during the follow-up period. Regarding the risk scores, CHADS 2≥1,CHA2DS2-VASc≥2, and CHA2DS2-VASc-M≥2 were significantly associated with mortality. The performance of all risk scores for predicting mortality was satisfactory (area under the curve:0.668, 0.668, and 0.681, respectively). Appraising secondary endpoints, we found that all three risk scores were associated with increased risk of acute respiratory distress syndrome, cardiac injury, acute kidney injury, and mechanical ventilation. Lastly, we revealed that all risk scores were significantly correlated with serum levels of laboratory biomarkers. Conclusion: Our analysis illustrated that the CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-Mscores could aid prognostication of unfavorable outcomes in COVID-19 patients. Therefore,these easily calculable methods could be integrated into the overall therapeutic strategy to guide the COVID-19 management more accurately.
Investigation of the association between cardio-metabolic risk factors, neurotrophins and gastric hormones among apparently healthy women: A cross-sectional analysis
Authors: Zeinalian Reihaneh , Arman Moghadam Dorsa , Pahlavani Naseh , Roshanravan Neda , Alizadeh Mohammad , Jabbari Masoumeh , Kheirouri Sorayya
Published: April 2022

Introduction: Although, some evidence has shown that obestatin, ghrelin, and neurotrophic factors can be involved in the development of cardio-metabolic risk factors, there are some contradictions in this regard. We aimed to investigate the association of serum neurotrophic factors and some gastric hormones with cardio-metabolic risk factors among apparently healthy women. Methods: In the present study, 90 apparently healthy women were recruited by a convenient sampling method from the nutrition counseling clinic in Tabriz, Iran. All participants need dietary counseling for weight loss and were recruited before receiving any dietary interventions. Anthropometric, biochemical, physical activity, and blood pressure (BP) measurements, as well as dietary assessment, were done in all participants. Results: Women who were in the highest tertile of serum obestatin levels (OR=0.118, 95% CI:0.035-0.396) had a significantly lower risk for development of hypertriglyceridemia compared to the reference group (P trend<0.001). Participants in the highest tertile of serum ghrelin had a significant lower risk of hypertriglyceridemia, hyperglycemia, low HDL-C, and MetS (Ptrend<0.05). Women who were in the higher tertile of serum NGF levels had a significantly lower risk for development of hypertriglyceridemia after adjustment for potential confounding variables (OR=0.091, 95% CI: 0.023-0.361 and OR=0.193, 95% CI: 0.057-0.649 respectively). Conclusion: In the current study serum levels of obestatin, NGF, and ghrelin were associated with some cardio-metabolic risk factors such as hypertriglyceridemia and MetS. It seems that these factors are associated with metabolic regulation. However, further studies are needed to substantiate this claim.
q-Analogue of New Subclass of Salagean-type Harmonic Univalent Functions defined by Subordination
Authors: Bayram Hasan , Yalçın Sibel
Published: April 2022

We introduce and investigate q-analogue of a new subclass of Salagean-type harmonic univalent functions defined by subordination. We first obtained a coefficient characterization of these functions. We give necessary and sufficient convolution conditions, distortion bounds, compactness and extreme points for this subclass of harmonic univalent functions with negative coefficients.
Servant Leadership And Life Satisfaction: The Mediating Role Of Life Goals And Psychological Needs
Authors: Liaqat Hamza , Ullah Farman , Gul Rehman
Published: April 2022

The objective of this study is to conceptualizethe proposed research framework of the private schools of Pakistan. The primary objective of this research is to test the relationship between servant leadership and life satisfaction with mediating effect of life goals and psychological needs. This study proposed two mediation effects of life goals and psychological needs between servant leadership and life satisfaction. The study has been tested using data collected from 254 respondents of private schools' teaching and administrative staff. The results of the study acknowledge that servant leadership negatively affects life satisfaction. Furthermore, the results acknowledge the significantmediation effect between servant leadership and life satisfaction. The results of the study will help private school leadership to improve leadership practices and give a better understanding of what an employee ultimately wants to achieve and how organizations and leaders will help in these phenomena.
Causal effect of pandemic COVID-19, gold and oil prices on United States economic policy uncertainty: Evidence from ARDL method
Authors: Siddique Asima , Khan Muhammad Asif , Khalid Ali Awais
Published: April 2022

The United States is the most significant economic power in the world. Therefore changes in economic indicators or economic policy of the United States will affect the whole world economy like the global financial crisis 2007-08. The first innovative study examines the effect of United States Coronavirus (COVID-19), oil, and gold prices on United States economic policy uncertainty. Autoregressive Distributed Lag Model(ARDL) is employed to get the long and short-run co-integration results. The outcome shows that (USCOVID_19 and OIL) significantly co-integrated in both the short and long run with United State Economic Policy of Uncertainty(USEPU) at a significant level. USCOVID-19 is positively short and long-run co-integrated, while oil is negatively short and long-run co-integrated with the economic uncertainty level of the USEPU. Only one variable of gold has no short and long-run co-integrated with USEPU.
Epistemologias e metodologias invertidas nas pesquisas colaborativas e solidárias em educação: desafios e perspectivas
Authors: Bomfim Natanael Reis , Pimentel Gabriela Sousa Rêgo
Published: April 2022

Este artigo é um convite à reflexão sobre os desafios e perspectivas nas pesquisas educacionais, sob a égide da interdisciplinaridade. Precipuamente, será abordado o processo de construção do objeto de estudo à transformação da realidade social, e o escape da rigidez do método para o rigor metodológico. Em seguida, a partir dos Grupos de Pesquisa Interdisciplinar de Pesquisa em Representações, Educação e Sustentabilidade (GIPRES) e Políticas Públicas e Gestão da Educação (EDUCATIO), da Universidade do Estado da Bahia, apresentam-se desenhos de pesquisas em representações sociais, gestão e políticas públicas aplicadas à educação na contemporaneidade.
Dinámica hídrica y balance hidrológico en la cuenca del embalse Lago del Fuerte, Tandil
Authors: Cifuentes Marisol Roxana , Rodríguez Corina Iris , Ruíz de Galarreta Víctor Alejandro , Gabellone Néstor Adrián
Published: April 2022

El conocimiento sobre la cantidad, calidad y dinámica de los recursos hídricos es uno de los puntos cruciales para tender hacia su gestión integrada. El objetivo fue caracterizar la dinámica hídrica de la cuenca del embalse Lago del Fuerte, de la ciudad de Tandil, y efectuar un balance hidrológico del cuerpo de agua con el propósito de generar información de base para la toma de decisiones y futuras investigaciones. El lago ha presentado problemas de eutrofización. Se encuentra emplazado en una cuenca serrana, la cual ha experimentado en los últimos años cambios en los usos del suelo. La metodología combinó la utilización de información antecedente, mediciones en campo y estimaciones de parámetros hidrológicos. Se evaluó la dinámica hídrica superficial y subterránea de la cuenca y se determinó el balance hidrológico del lago. El principal ingreso de agua al lago fue superficial, mediante los arroyos afluentes, mientras que en menor medida ingresó agua subterráneamente y por precipitación directa. El mayor egreso se dio por la salida del embalse y una proporción menor por evaporación. Los volúmenes de entrada y salida fueron similares, a pesar del exceso hídrico del período, con una variación de almacenaje despreciable, debido al tipo de descarga de la presa.
ORO BLANCO:
Authors: Márquez Rodríguez Joel Márquez Rodríguez
Published: April 2022

En el siglo XV se produjo la conquista europea de las islas Canarias y su integración en el incipiente circuito comercial entre Europa, América y África. La introducción de la caña azucarera representó el primer cultivo de exportación de la economía insular, a través de su principal producto: el azúcar. Desde principios del presente siglo se ha llevado a cabo un progreso paulatino en la investigación arqueológica y en el estudio de las huellas materiales que la actividad azucarera dejó en las islas, coincidiendo con una mayor valoración de la información que la arqueología moderna o histórica puede aportar al conocimien- to histórico. En el presente artículo se pretende ofrecer una visión integral de los trabajos desarrollados hasta el momento, así como la recepción por parte de la sociedad canaria del patrimonio histórico rela- cionado con el azúcar.
CONOCIMIENTOS, CREENCIAS Y LA NAVAjA DE OCCAM
Authors: Ramos Mariano Sergio Ramos
Published: April 2022

En este trabajo trato algunas cuestiones epistemológicas y de procedimientos seguidos en las investiga- ciones que se proponen alcanzar conocimiento. Presentaré brevemente dos casos de campos de batalla, de los que uno de ellos ha sido tomado como matriz metodológica aplicable a otros sitios del mismo tipo. Finalmente analizaré algunos procesos de formación y transformación de sitios y haré algunas reflexiones.
SAĞLIK HİZMETLERİ PAZARLAMASI ÜZERİNE BİR MODEL ÖNERİSİ: KAMU VE ÖZEL HASTANE ÖRNEĞİ
Authors: Yeşilkaya Büşra Havva , Akalın Betül
Published: April 2022

Araştırma kamu ve özel sağlık kurumları açısından; hizmet kalitesi ve sosyal medya kullanımının marka imajına, marka imajının da tercih ve önerme niyeti üzerine etkisini ortaya koymaya çalışmaktadır. Kamu ve özel hastanede muayene olmuş 384 kişi bu araştırmanın örneklemini oluşturmaktadır. Araştırmadaki verilerin analizinde, sağlık hizmetleri pazarlama modeli ölçeğine yönelik açıklayıcı faktör analizi, daha sonra yol analizi ile değişkenler arası ilişkilere bakılmıştır. Sağlık Hizmetleri Pazarlama Modeline yönelik betimsel analiz sonuçları incelendikten sonra hastaların kişisel bilgilerine göre değişkenlerin grup ortalama puanlarının farklılaşma durumu incelenirken normal dağılım varsayımını sağlayan değişkenlerin iki grup karşılaştırmalarında “bağımsız örneklem t testi” üç ve üzeri grup karşılaştırmalarında “ANOVA” kullanılmıştır. Anova testi sonucunda anlamlı farklılığın olduğu değişkenlerde Post-Hoc LSD testi uygulanmıştır. Araştırmanın amacı doğrultusunda yapısal eşitlik modeli kurulmuştur. Bu modele göre; hizmet kalitesinin marka imajı üzerinde anlamlı bir etkisinin olduğu (ß= 0,868), sağlık hizmetlerinde sosyal medya kullanımının marka imajı üzerinde anlamlı bir etkisinin olduğu (ß= 0,085), hizmet kalitesinin marka imajı üzerinde sağlık hizmetlerinde sosyal medya kullanımına kıyasla daha fazla etkisinin olduğu ve marka imajının tercih ve önerme niyeti üzerinde güçlü bir etkisinin olduğu (ß= 923) sonucuna ulaşılmıştır. Bu bulgular doğrultusunda sağlık hizmetlerinde hizmet kalitesinin ve sosyal medya kullanımın marka imajını etkileyen bir unsur olduğu ve marka imajının artmasının da hastaneye gelen kişilerin tavsiye etme davranışlarını da arttıracağı sonucuna ulaşılmıştır.
¿Cuán lejos viajarías por nafta más barata?
Authors:   , Pizzi Francisco
Published: April 2022

Explotando una reforma particular en los impuestos a los combustibles y utilizando un modelo simple de competencia horizontal, se muestra como el equilibrio de mercado se modifica como consecuencia del efecto de un cambio impositivo. La reforma es la extensión de la zona de exención del impuesto a los combustibles desde la región patagónica en Argentina hacia 4 provincias contiguas en diciembre de 2015. Después del cambio, los precios finales de venta para los consumidores caen un 20% en las zonas exentas; y las estaciones próximas a la nueva zona de exención (pero no exentas) ven reducidos sus precios y sus ventas. El efecto negativo sobre precios y volúmenes se atenúa a medida que la estación de servicio se encuentra más alejada de la zona de exención. Los efectos encontrados son robustos a distintas especificaciones. Los resultados ejemplifican el papel de los incentivos fiscales sobre las decisiones de los agentes y el efecto de la competencia sobre precios, aun en mercados con altos niveles de regulación.
Two-Eyed Seeing and Scientific Holism in a New Science|Environment|Health Pedagogy
Authors: Zeyer Albert , Nuria Álvaro , Claussen Christina , Enzingmüller Carolin , Gavidia Valentín , Malmberg Claes , Mayoral Olga , Parchmann Ilka , Urbas Anders , Kremer Kerstin
Published: April 2022

Science|Environment|Health (S|E|H) is a new science pedagogy that aims at promoting the mutual benefit between the three educational fields of science education, environmental education, and health education. Holism and its conceptualisation has become an important topic in recent S|E|H work. In this paper, featuring the invited symposium of the ESERA special interest group 4 at the ESERA conference 2021, we suggest the concept of Two-Eyed Seeing as a basis for the definition of scientific holism in S|E|H. Two-Eyed Seeing as a metaphor was introduced by science education researchers working with Canadian aborigines. Based on Sellars’s concept of stereoscopic view, we conceptualize Two-Eyed Seeing in S|E|H through an ontological framework. We define scientific holism as the “eye switch” from the scientific image to students’ life-world image, a transition that we consider as equally important as the - more common - reductionist “eye switch” from students’ life-worlds back to the scientific image. Two-Eyed Seeing may then be understood as a continuous circulation of repeated “eye switches” between life-world image and scientific image. We illustrate this approach by three symposium contributions - communicating the meta-organism in school, scientific holism against eco- and health depression, and a holistic visual tool to approach S|E|H competences – and we discuss consequences for teaching and research in science education. We point out that, in a new S|E|H pedagogy and beyond, Two-Eyed Seeing may be a helpful extension to the well-established socio-scientific issues approach.
ENHANCING ENTREPRENEURIAL SKILLS THROUGH CO-OPETITIVE LEARNING EXPERIENCE: A CASE STUDY IN A SPANISH UNIVERSITY
Authors: Erdmann Anett , García-Monleón Fernando , Nuñez-Canal Margarita
Published: April 2022

Global competition and digital market forces imply opportunities and threats in an increasingly fast and competitive job market. In this context, motivated learning through collaboration or cooperation have been extensively studied to develop necessary skills to be competitive. However, in undergraduate teaching little attention has been given to learning through competition and co-opetition, which is more common in entrepreneurial education. This paper proposes and tests a new classroom methodology where undergraduate students in the course Microeconomics interact in teams playing out features of the four C’s of game-based learning in an entrepreneurial environment: cooperation, collaboration, competition and co-opetition. The pedagogical pilot-project, dubbed as “Micro-Challenge”, is a peer-based student challenge which has been implemented in face-to-face classes as well as in a hybrid classroom. A posterior analysis of survey data and academic results, using regression analysis, reveals that the development of collaborative skills and team-based skills depend on personal characteristics and expertise while there is no significant effect of academic performance. Moreover, women are more likely to improve team-working or collaborative skills through the proposed challenge than men and engagement in terms of induced learning effect is found to be higher for students who are already endowed with a high level of competitive or collaborative attitude.
DAMPAK SUKU BUNGA, INFLASI, NILAI TUKAR, DAN JUMLAH UANG BEREDAR TERHADAP INDEKS HARGA SAHAM GABUNGAN
Authors: Pradita Afrila Eki , Fidyah Feny
Published: April 2022

Penelitian ini bertujuan untuk menganalisa dampak suku bunga, inflasi, nilai tukar, dan jumlah uang beredar terhadap indeks harga saham gabungan. Periode analisis data yang digunakan dalam penelitian ini adalah data tanggal 1 Januari 2016 hingga 31 Januari 2020. Data yang digunakan adalah data sekunder. Metode analisis regresi linear berganda digunakan dalam penelitian ini, dengan menggunakan uji asumsi klasik, uji statistik t, uji statistik F, dan uji koefisien determinasi. Berdasarkan hasil pengujian didapatkan bahwa suku bunga secara parsial tidak berdampak pada IHSG. Sedangkan inflasi, nilai tukar, dan, jumlah uang beredar berdampak pada IHSG. Secara simultan suku bunga, inflasi, nilai tukar, dan jumlah uang beredar berdampak pada harga saham IHSG.
Pengembangan Intelektualitas melalui Literasi Membaca bagi Karang Taruna Desa Kota Daro II Kabupaten Ogan Ilir
Authors:   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan, Widyanata Fera , Apriani Deassy ,   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan, Susetyo Didik ,   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan, Effendi Abbas ,   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan, Haidir M. Fajri ,   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan, Sinta Harta ,   Fakultas Ekonomi, Universitas Sriwijaya, Sumatera Selatan
Published: April 2022

Abstract Purpose: This community activity aims to increase literacy in reading interest in the younger generation of the Sriwijaya University fostered village, namely Kota Daro II Village, Rantau Panjang District, Ogan Ilir Regency. The selected target is youth members of the youth organization, which is about 20 to 30 people as the initiators of reading literacy in the community, especially children. This activity was carried out from August to October 2021 with several visits. Method: Carried out in stages including question and answer, introduction and empowerment. These stages are the pre-activity stage and the activity implementation stage. Result: This activity have an impact on increasing the enthusiasm and desire of service participants to get used to reading as well as being able to implement the importance of reading culture to the local community. It is hoped that it can foster interest in reading among children and youth of Kota Daro II.
O SISTEMA INTERNACIONAL DE PROTEÇÃO DE MIGRANTES E REFUGIADOS:
Authors: TANAKA DOS SANTOS DENISE , TANAKA DOS SANTOS DENISE
Published: April 2022

RESUMO: O presente trabalho pretende abordar, de forma breve, o sistema internacional de proteção dos direitos humanos de migrantes e refugiados. A construção do sistema jurídico de proteção desse grupo vulnerável de pessoas humanas parte entre avanços e retrocessos. Assim, buscar-se-á, segundo uma metodologia sistemática, compreender esse tema em face de restrições e de suspensões de direitos decorrentes da Pandemia.
MONITORAMENTO SISTEMÁTICO DO ORÇAMENTO PÚBLICO DA COVID-19 E A ANÁLISE ECONÔMICA DO DIREITO À SAÚDE
Authors: RIBEIRO PEREIRA NUNES CLAUDIA , SANTOS FERNANDO RANGEL ALVAREZ DOS
Published: April 2022

Em março de 2020, o Ministro da Saúde do Brasil anunciou que o Sistema Único de Saúde não possuía orçamento suficiente para apoiar as novas despesas com as doenças causadas pelo novo Coronavírus. Dias depois, ao observar o funcionamento do monitoramento sistemático do orçamento, o Congresso Nacional alterou os identificadores de resultado primário e propôs créditos suplementares às despesas da doença. Neste contexto, o objetivo do presente artigo é verificar qual é o vínculo entre o sistema orçamentário brasileiro e as diretrizes dos Objetivos de Desenvolvimento Sustentável 3 (Saúde Pública e Bem-Estar) – ODS 3, tendo como panorama de fundo a necessidade de especificar verbas para uma política pública emergencial como resposta à pandemia. Busca-se compreender o fenômeno à luz da Análise Econômica do Direito à Saúde no Brasil, no contexto do Estado de Bem-Estar, na era da pandemia. A pesquisa se vale de estudos bibliográfico, documental, em especial a legislação concernente à Constituição Federal, ao Relatório Brudtland e aos dados secundários obtidos nas legislações relativas ao tema, considerando-se as particularidades histórico-sociais do Brasil, argumentando-se sobre a importância da Análise Econômica do Direito com metodologia exploratória e descritiva e o método hipotético-dedutivo.
Forecasting the Transmission Trends of Respiratory Infectious Diseases with an Exposure-Risk-Based Model at the Microscopic Level
Authors: Cui Ziwei , Cai Ming , Xiao Yao , Zhu Zheng , Yang Mofeng , Chen Gongbo
Published: April 2022

Respiratory infectious diseases (e.g., COVID-19) have brought huge damages to human society, and the accurate prediction of their transmission trends is essential for both the health system and policymakers. Most related studies focus on epidemic trend forecasting at the macroscopic level, which ignores the microscopic social interactions among individuals. Meanwhile, current microscopic models are still not able to sufficiently decipher the individual-based spreading process and lack valid quantitative tests. To tackle these problems, we propose an exposure-risk-based model at the microscopic level, including 4 modules: individual movement, virion-laden droplet movement, individual exposure risk estimation, and prediction of transmission trends. Firstly, the front two modules reproduce the movements of individuals and the droplets of infectors’ expiratory activities, respectively. Then, the outputs are fed to the third module to estimate the personal exposure risk. Finally, the number of new cases is predicted in the final module. By predicting the new COVID-19 cases in the United States, the performances of our model and 4 other existing macroscopic or microscopic models are compared. Specifically, the mean absolute error, root mean square error, and mean absolute percentage error provided by the proposed model are respectively 2,454.70, 3,170.51, and 3.38% smaller than the minimum results of comparison models. The quantitative results reveal that our model can accurately predict the transmission trends from a microscopic perspective, and it can benefit the further investigation of many microscopic disease transmission factors (e.g., non-walkable areas and facility layouts).