bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUATION OF IMPLEMENTATION OF CLOUD COMPUTING in PT. SUPRANUSA SINDATA
Authors: Ramadhan Andika
Published: July 2020

THE RESEARCH OBJECTIVES in this thesis is as evaluation of the implementation of Cloud Computing which has been in implementation in PT. Supranusa Sindata in order to develop into better again. METHODS were used in this study include the collection of journals and books as reference or grounding in analyzing. Data obtained from questionnaires to 100 respondents. The data were analyzed using factor analysis method after continued using regression analysis and designed with the IT Balanced Scorecard method. RESULTS OBTAINED is a form factor that can be used by PT. Supranusa Sindata to evaluate the implementation of Cloud Computing, technique systems engineering factors of cloud computing, cloud computing system management, performance measurement system of cloud computing, cloud computing system effectiveness. CONCLUSION with the model that can be used to evaluate the implementation of cloud computing and the design of strategic performance measurement using IT Balanced Scorecard is expected to grow so will affect the company's business performance and increase employee knowledge.
Effects of some commonly used biopesticides on the survival and virulence of native entomopathogenic nematode isolates
Authors: YÜKSEL Ebubekir , CANHILAL Ramazan
Published: July 2020

The compatibility of the use of native Turkish entomopathogenic nematode (EPN) isolates, Heterorhabditis bacteriophora FLH-4H (Poinar, 1975) (Rhabditida: Heterorhabditidae), Steinernema carpocapsae KCS-4S (Weiser, 1955) (Rhabditida: Steinernematidae) and Steinernema feltiae KMP-9S (Filipjev, 1934), with two biopesticides, 40 g/ L Azadirachtin and 480 g/ L Spinosad, was investigated under laboratory conditions. The effects of these biopesticides on the viability and virulence of IJs of EPN isolates was studied by direct exposure to the biopesticides for 24 h and 48 h at the highest concentrations recommended for field application. Survival rates of the EPN isolates ranged between 5% and 21%. Heterorhabditis bacteriophora FLH-4H was the most tolerant isolate, with mortality of IJs not exceeding 12% for both exposure times. The biopesticides did not affect the virulence of the EPNs, with the mortality of Galleria mellonella L. (Lepidoptera: Pyralidae) larvae ranging between 70% and 95%.
A new larval parasitoid of Heliothis peltigera (Denis & Schiffermüller) (Lepidoptera: Noctuidae), Aleiodes (Chelonorhogas) miniatus (Herrich-Schäffer) (Hymenoptera: Braconidae: Rogadinae)
Authors: AYTEN Sevgi , BEYARSLAN Ahmet , ÜLGENTÜRK Selma
Published: July 2020

Safflower is a plant grown for a wide range of industrial uses. A survey revealed that the larvae of Heliothis peltigera (Denis & Schiffermüller, 1775) (Lepidoptera: Noctuidae), an important safflower pest in Ankara Province, Turkey, are parasitized by Aleiodes (Chelonorhogas) miniatus (Herrich-Schäffer, 1838) (Hymenoptera: Braconidae: Rogadinae). This is the first report of this host-parasitoid relationship worldwide.
Environmental Practices of University Teachers in Pakistan
Authors: Kalsoom Qudsia
Published: July 2020

The study is a part of the larger project on environmental practices in Pakistani universities.
The current study has
investigated the environmental practices (complex of behaviours and attitudes) of
the university teachers in Pakistan. To achieve the study purpose, a
questionnaire was developed in the light of literature on environmental
education, consumption behaviours and attitude towards environment.
Experimental study of Organic Rankine cycle system by using R141b as working fluid
Authors: Kareem Aya H.A .Kareem , Al-Hamadan Ali A. F.
Published: July 2020

Organic Rankine cycle (ORC) is one of the renewable energy to generate power at low temperatures; however, the thermal and physical properties data of the working fluid in this system are limited. In this regards, the experimental study by using R-141b as the working fluid and hot water (i.e. 50°C and 90°C) on the ORC system was conducted in order to evaluate the ORC performance via changing temperatures. Further, the air compressor was modified to act as a multi-vane expander in the ORC system. Energy and exergy analysis of ORC system was done by using Engineering Equation Solver (EES) program.

It was found that the performance of the expander is acceptable and suitable for operating conditions. In addition, the heat source temperature has a direct effect on expander performance. The higher temperatures of the heat source led to an increase the expander inlet temperature. This system satisfied maximum thermal and exergy efficiency and they found equal to 1.8 % and 21%, respectively. Moreover, the rotation speed and power of expander are equal to 1200 RPM and 2.331 kW respectively. It was concluded that the working fluid R-141b is suitable for ORC system due to consider the working fluid that do not need high temperatures to evaporate.
Immunitarianism: defence and sacrifice in the politics of Covid-19
Authors: Ajana Btihaj
Published: July 2020

As witnessed over the last year, immunity emerged as one of most highly debated topics in the current Covid-19 pandemic. Countries around the globe have been debating whether herd immunity or lockdown is the best response, as the race continues for the development and rollout of effective vaccines against coronavirus and as the economic costs of implementing strict containment measures are weighed against public health costs. What became evident all the more is that immunity is precisely what bridges between biological life and political life in the current climate, be it in terms of the contentious notion of herd immunity, the geopolitical struggle for vaccines, or the possible emergence of “Covid-elite”, i.e. holders of so-called “immunity passports”. Immunity, as such, is certainly not only a matter of science and biology alone, but is inherently political in the way that pandemics themselves are often highly politicised. Drawing on the work of Roberto Esposito and other literature from the field of biopolitics and immunology, this paper provides a critical examination of the concept of immunity in light of the recent events, highlighting the intersections between the politics of defence and the politics of sacrifice which animate governments’ immunitary responses to the Covid-19 pandemic. The paper ends with a discussion on the forms of solidarity and local initiatives that have been mobilised during the current pandemic and their potential for an affirmative form of biopolitics. Overall, the main aim of this paper is to provide a critical cultural and philosophical analysis of Covid-19 debates and responses, and a nuanced account on the biopolitical effects of the current pandemic, highlighting the paradoxical nature of immunity which straddles at once negative practices of defence and sacrifice as well as affirmative forms of community and solidarity beyond state apparatuses.
Promises to keep: speech acts and the value of reflective knowledge
Authors: Turri John
Published: July 2020

This paper offers a new account of reflective knowledge’s value, building on recent work on the epistemic norms of speech acts. Reflective knowledge is valuable because it licenses us to make guarantees and promises.
TRPM2 is differentially expressed in high-grade serous ovarian cancers.
Authors: Mamoor Shahan
Published: July 2020

Ovarian cancer is the most lethal gynecologic cancer (1). We sought to identify genes associated with high-grade serous ovarian cancer (HGSC) by comparing global gene expression profiles of normal ovary with that of primary tumors from women diagnosed with HGSC using published microarray data (2, 3). We found significant differential expression of the gene encoding the complement component TRPM2 in high-grade serous ovarian tumors.
SISTEM PEMBELAJARAN DARING MENGGUNAKAN MEDIA ONLINE PADA ERA COVID-19
Authors: Nadia
Published: July 2020

Pandemi Covid-19 telah menjadi permasalahan dunia saat ini, hingga menggangu proses belajar mengajar secara konvensional. Penyebaran Covid-19 yang sangat cepat dari Eropa dan Asia Hingga seluruh Dunia membuat pelaksanaan pembelajaran tatap muka seperti biasanya di lingkungan kampus harus beralih menjadi pembelajaran daring yang menggunakan media online sebagai solusi pada Era Covid-19 dalam proses pembelajarandi Dunia, dan juga sebagai tindakan untuk mengurangi penyebaran Covid-19.
Konsep “Mecaru” Dalam Budaya Bali Sebagai Jembatan Penginjilan Terhadap Orang Bali
Authors: Fransiska Ni Nyoman
Published: July 2020

Dalam Perjanjian Baru kurban berupa kambing dan domba dianggap lambang saja, “sebab tidak mungkin darah lembu jantan atau darah domba jantan menghapuskan dosa (Ibr. 10:4). Sedangkan, darah Kristus yang dipersembahkan sekali untuk selama-lamanya merupakan kurban yang sempurna.” 1 Korban yang layak menggantikan kita di hadapan Allah haruslah lebih tinggi dari seekor hewan. Karena tidak mungkin darah domba jantan menghapuskan dosa (Ibrani 10:4), maka korban yang dapat diterima Allah hanyalah korban seorang manusia.
Review of "Knowledge and Skepticism" edited by Joseph Campbell, Michael O'Rourke, and Harry Silverstein
Authors: Turri John
Published: July 2020

A review of the collection "Knowledge and Skepticism" edited by Joseph Campbell, Michael O'Rourke, and Harry Silverstein.
Effects of human-animal interactions on affect and cognition
Authors: Thayer Elise , Stevens Jeffrey R
Published: July 2020

Human-animal interaction has clear positive effects on people's affect and stress. But less is known about how animal interactions influence cognition. We draw parallels between animal interactions and exposure to natural environments, a research area that shows clear improvements in cognitive performance. The aim of this study is to investigate whether interacting with animals similarly enhances cognitive performance, specifically executive functioning. To test this, we conducted two experiments in which we had participants self-report their affect and complete a series of cognitive tasks (long-term memory, attentional control, and working memory) before and after either a brief interaction with a dog or a control activity. We found that interacting with a dog improved positive affect and decreased negative affect (in one of the two experiments), stress, and anxiety compared to the control condition. However, we did not find effects of animal interaction on long-term memory, attentional control, or working memory. Thus, we replicated existing findings providing evidence that interacting with animals can improve affect, but we did not find similar improvements in cognitive performance. These results suggest that either our interaction was not of sufficient dose or timed appropriately to elicit effects on cognition or the mechanisms underlying effects of human-animal interaction on cognition differ from effects generated by other cognition-enhancing interventions such as exposure to nature. Future research should continue to increase knowledge of the connection between nature exposure and human-animal interaction studies to build our understanding of cognition in response to animal interactions.
Mothers' and fathers' quantitative and qualitative parenting in relation to children's emotional adjustment: A between- and within-family investigation
Authors: Van Lissa Caspar J. , Keizer Renske
Published: July 2020

This longitudinal study of Australian families (n = 1884, from age 6-12) examined how fathers' and mothers' quantitative involvement (time spent on childcare) and qualitative involvement (specific parenting behaviors) relate to children's emotional adjustment development. We used dynamic structural equation modeling to disentangle stable between-family differences from within-family fluctuations in qualitative parenting and emotional adjustment, allowing us to investigate the direction of effects between parents and children. Because fathers have been theorized to contribute uniquely to emotional adjustment development, we examined differences between mothers and fathers, and the interplay between parent- and child sex. We further examined whether between-family differences in quantitative involvement, operationalized as joint (total) and relative (one parent does more) involvement, predict qualitative parenting behaviors and emotional adjustment, and moderate the within-family interplay between them. Results revealed between-family correlations of qualitative involvement with emotional adjustment. Evidence for significant average within-family effects was limited to a parenting effect of maternal warmth, and several child effects, which indicated that emotional adjustment evokes changes in parenting. Parenting effects varied substantially across families however, especially for fathers. Between-family differences in quantitative involvement explained some of these differences. When joint quantitative involvement was higher, both parents engaged in more desirable qualitative parenting. When mothers were relatively more involved than fathers, fathers displayed less desirable qualitative parenting, and children were less well-adjusted. There was some limited evidence that within-family predictive effects were moderated by quantitative involvement, particularly relative involvement. These findings suggest that all family members benefit from a more equal childcare distribution.
Associations Between Higher-Order Values Vary with Age, Education, and Income
Authors: Rudnev Maksim
Published: July 2020

A theory of basic human values relies on the similarity of value structures across countries. It has been well established that the quasi-circumplex value structure as a whole is indeed universal. However, less attention has been paid to the associations between specific values. This study investigated associations between four higher-order values across age, education, and income groups. We analyzed the data from national representative samples collected in 29 countries as part of the fourth round of the European Social Survey with a series of multilevel regressions. Younger age, higher levels of education and income coincided with higher independence of the four adjacent higher-order values, whereas among older, less educated, and less wealthy groups, values tended to merge into a single dimension of Social versus Person Focus. These differences were slightly weaker in more economically developed countries. The group differences in value associations may follow from corresponding differences in the degree of societal and individual empowerment, cognitive abilities, and socialization experiences. Accounting for the individual differences in relations between values may bring deeper understanding and higher predictive power to the studies of links between values and various behaviors or attitudes. , value structure, value interactions, European Social Survey
Knowledge and Practices on Menstrual Hygiene Management Among Adolescent Girls of Kaski District, Nepal
Authors: Poudel Sasmita , Gautam Dipesh
Published: July 2020

The study was conducted to understand the cultural and social practices and knowledge prevailing on menstrual hygiene management among adolescent girls in Nepal. A school-based cross-sectional study was conducted among 122 adolescent girls of class VII to X at three schools of Kaski district, Nepal. A pre-tested structured questionnaire was used for assessing socio-demographic profiles, knowledge, and experiences on menstruation, practices (social and cultural) regarding menstrual hygiene management. The data collected were analysed using SPSS version 23 for windows. The mean age at menarche was found to be 12.5±0.9. The majority (73%) girls were aware of menstruation prior to the attainment of it. Most of them got the information from mother (45.9%), the majority (69.7%) used sanitary pad as the absorbents, however, most of them (78.4%) throw the sanitary pad in the garbage. Many cultural and social taboos and restrictions were found associated with menstruation. The majority (91.8%) were not allowed to participate in religious activities, 45.1% were not allowed to touch things in the house, two- thirds (67.2%) were not allowed to cook, and 60.7% were not allowed to enter the kitchen. Most of the adolescent girls were isolated even from normal daily activities and they were not happy with these restrictions during the menstruation. Instead, they urged the need for more support, care, and hygienic practices for proper hygiene management to lead a healthy life. This paper reflects the actual knowledge and practices prevailed in the society during menstruation and emphasizes on providing the correct knowledge on health and helping to correctly practice hygiene during menstruation.

Int. J. Soc. Sc. Manage. Vol. 7, Issue-3: 169-175
A Study on Depression in Returnee Female Migrant Workers
Authors: Singh Pradip Man , Joshi Neelam , Prajapati Anita
Published: July 2020

Introduction: Women seeking foreign employment have been rising in Nepal. Changing scenarios, like: household structure and women's desire to work outside have provided opportunity for women from countries like Nepal to become independent and give financial support in family. For female migrant workers, it is not easy to adjust to new country because of difference in socio-cultural aspect, poor working and living condition. Many of them suffer from health issues including psychiatric morbidity.

Objective: To estimate the prevalence of depression and the socio-demographic profiles of returnee female Nepalese migrant workers.

Methods: A descriptive study was undertaken in Emergency Shelter House of an NGO, among returnee female migrant workers using semi-structured questionnaire, interview and Hamilton’s Depression Rating Scale (HAM-D). Ethical clearance and consent were taken.

Results: The HAM-D score showed that 71.5% of the subjects were depressed which was analyzed with various socio-demographic profiles and the factors of foreign employment. A strong significance was seen with residential area (p= 0.004). The level of depression was not statistically significant with age, education, marital status, earning of husband and monthly household income.

Conclusion: Depressive symptoms were common among returnee female migrant workers. Regular mental health assessment of returnee women migrant workers should be done. This will help to minimize the psychiatric morbidity among them.
Prevalence of Mild-Cognitive-Impairment and Depression among Elderly Clients in Selected Wards of Baraha Municipality: A Cross-Sectional Study
Authors: Pradhan Nirmala , Adhikari Baikuntha Raj , Lama Sami , Shrestha Sharmila , Sigdel Rambha
Published: July 2020

Introduction: Mild-Cognitive-Impairment (MCI) is an intermediate state between normal cognitive ageing and dementia. Identification of MCI is thought to be crucial to early intervention.

Objectives: To assess Mild-Cognitive-Impairment and Depression among elderly clients and to find out the associations between Mild-Cognitive-Impairment and Depression and socio-demographic variables.

Methods: A descriptive, cross-sectional study design was adopted. A total of 115 elderly clients who fulfilled the selection criteria were enrolled using purposive sampling technique. Montreal Cognitive Assessment (MoCA) and Geriatric Depression Scale were used with Interview technique. Those elderly clients were selected from the 2 wards of Baraha Municipality.

Results: Majority of the subjects (68.7%) were from between 60-70 years. More of the elderly clients were females (54.8%). Maximum (81.7%) were illiterate. About 35.7% had the history of medical and psychiatric illness. From the total sample, 39.1% had issues with memory. In case of Montreal Cognitive Assessment (MoCA), 93.0% was screened with Mild-Cognitive-Impairment. And, 60.9%of the elderly clients were screened as Depression. With regard to the associations between mild cognitive impairment and selected demographic variables, significant associations were found with gender, education level, marital status and previous history of medical/ psychiatric history. The correlation between MoCA score and geriatric depression score showed a negative relationship.

Conclusion: Many elderly people in a community have Mild-Cognitive-Impairment and Depression. This study added evidence on prevalence of Mild-Cognitive-Impairment and Depression among geriatric clients in a community-dwelling.
Evaluation of the World Health Organization outcome standards at the early and late post-operative visits following cataract surgery
Authors: Meyer Jay J , Murray Neil L
Published: July 2020

Introduction: This study was conducted to determine whether the World Health Organization (WHO) visual acuity standards are correlated between the early and late early post-operative periods following phacoemulsification (phaco) and small incision extracapsular cataract surgery (SICS). Secondary aims were to compare visual outcomes and complications following SICS and phaco.

Methods: Retrospective cohort study following phaco and SICS performed by one surgeon. Primary outcome measures included uncorrected visual acuity (UCVA) and best corrected visual acuity (BCVA) at the early (≤72 hours) and late (≥21 days) post-operative visits. Secondary outcome measures included complications and astigmatism.

Results: 705 eyes were studied (509 phaco, 196 SICS). The correlation for UCVA between early and late follow-up examinations was higher for phaco (rs=0.58) compared to SICS (rs=0.45, p=0.04) while correlation for BCVA was similar (phaco,rs=0.52; SICS, rs=0.47; p=0.44). At the early post-operative visit, a higher proportion in the phaco group achieved ≥6/18 UCVA (81.5% phaco vs 64.8% SICS, p<0.0001) and BCVA (87.8% phaco vs 73.5% SICS, p<0.0001). At the late post-operative visit, a higher proportion following phaco also achieved ≥6/18 UCVA (93.9% phaco vs 85.2% SICS, p=0.0004) and BCVA (96.9% phaco vs 91.3% SICS, p=0.004). After exclusion of eyes with pre-existing ocular comorbidities, a similar proportion had ≥6/18 late UCVA (98.9% phaco vs 96.9% SICS, p=0.22) and BCVA (100% phaco vs 99.2% SICS, p=0.27).

Conclusions: Early and late post-operative WHO visual acuity levels are correlated, but not equivalent, following both phaco and SICS. In eyes without comorbidities, similar final visual outcomes can be achieved after phaco and SICS.
Macular function assessment by multifocal electroretinogram and microperimetry in macular hole and correlation with visual acuity
Authors: Dalan Daleena , Jaishankar Durgasri , Madhu Abinaya , Mani Karthiga , Ratra Dhanashree
Published: July 2020

Background: Functional outcome of macular hole (MH) surgery can be better assessed with multifocal electroretinogram (mfERG) and microperimetry (MP). It might provide better assessment than the Snellen visual acuity alone.

Objectives: To evaluate macular function with mfERG and microperimetry, and assess their correlation with visual acuity in MH.

Materials and Methods: A prospective study was done in patients with unilateral,idiopathic full thickness MH. Standard surgery with vitrectomy, internal limiting membrane peeling and gas tamponade was done. Snellen and logMAR visual acuity, mfERG, microperimetry and optical coherence tomography were done pre and postoperatively.

Results: Twenty six patients with unilateral macular hole and twenty five age matched controls were included. The mean age of patients was 59.92±9.39 years (range: 40 to 74 years). All the holes were closed after surgery (two required second surgery). The mean visual acuity improved from 0.77±0.34 logMAR to 0.43±0.36 (p =0.03). The mfERG amplitudes differed ring wise, but the average amplitude changed from 26.31±8.82 to 20.52±7.11 (p =0.03). The mean retinal sensitivity changed from 12.98±2.59 to 13.42±2.53 (p =0.11). There was significant correlation between visual acuity and mfERG amplitudes and retinal sensitivity. Regression equations to predict visual outcome could be derived.

Conclusions: In MH, mfERG and microperimetry show reduced responses, delay in recovery of function. They show a strong correlation with visual acuity. It is possible to predict vision after surgery with the help of mfERG and MP. Improved ability to predict visual outcome can increase the utility of anatomic success predictors.
Wprowadzenie
Authors: Bender Agnieszka , Janas Janina
Published: July 2020

Wprowadzenie
Il ritratto di Jan Grotkowski nei componimenti di Jan Andrzej Morsztyn e la questione delle “somme napoletane” [Literacki portret Jana Grotkowskiego w utworach Jana Andrzeja Morsztyna i kwestia „sum neapolitańskich”]
Authors: Janas Janina
Published: July 2020

Autorka artykułu kreśli literacki portret Jana Grotkowskiego (zapomnianego poety doby baroku) na podstawie czterech utworów poetyckich Jana Andrzeja Morsztyna. Tym sposobem z mroku niepamięci wyłania się ciekawa postać literata, dyplomaty, wpływowego uczestnika ówczesnej polityki międzynarodowej. Z postacią królowej Bony łączy go dopiero tajemnicza śmierć. Poeta wpisuje się tym samym na listę osób, które jak stwierdza Kantecki, „padły ofiarą sprawy, nad którą jak gdyby ciążyła klątwa królowej Bony”. Próbując rozwikłać kwestię „sum neapolitańskich”, Grotkowski, podobnie jak Reszka, Mąkowski i inni, zmarł w niewyjaśnionych okolicznościach.
Nazionale e liberale, il costituzionalismo del Risorgimento italiano [Narodowy i liberalny. Konstytucjonalizm włoskiego Risorgimento]
Authors: Griffo Maurizio
Published: July 2020

Włoskie Risorgimento, czyli proces historyczny, który doprowadził do zjednoczenia i niezależności Włoch, charakteryzuje się ciągłym sprzężeniem zasady narodowej z żądaniem instytucji wolności. Autor artykułu rekonstruuje ten proces na podstawie przełomowych momentów (wskazuje na trzy kluczowe zdarzenia), koncentrując się na fazie po 1848 roku, kiedy tylko Królestwo Sardynii utrzymało konstytucję, stając się tym samym istotnym punktem odniesienia dla ruchu patriotycznego.
Miron Costin – cronista e poeta
Authors: Janas Janina
Published: July 2020

The volume is based on the analysis of the historiographic and literary work of Miron Costin, who held positions of primary importance in the military, administrative and political life of the Principality of Moldavia during the central decades of the seventeenth century. In particular, are examined the narrative structures of his chronicles, which often are inspired by the creations of contemporary and previous Polish historians. Furthermore, the contribution to the affirmation of the latinity of the Romanian people is clarified, when the question had not yet been put on the agenda. Moreover, the echoes of Greek and Latin classicism are identified in the verses of the poem La vita del mondo (The life of the world), steeped in motifs and modules of the overflowing spirit of the Baroque era.
STEGANOGRAFI DENGAN AES PADA MEDIA SUARA BERBASIS INTERNET
Authors: Perwira Rifki Indra , Prasetyo Dessyanto Boedi , Haryanto Fandi Ahmad Juni
Published: July 2020

Information is an important part of the current era. Information has become a necessity so as not to be left behind by the times. By utilizing information, ideas and innovations will emerge. This information can be used for the benefit of many people. The more developed means of communication, the more the use of information is also developing. With the increasing number of ways to access this information, we need an application that can be used to secure information by storing information in containers such as sound, so that information can not be known by others. Steganography is a file hiding technique that becomes confidential so that other people do not understand the secret message that is in it. Cryptography is the science and art of secure messages. Utilizing sound as a media to insert secret messages, as well as adding cryptography as a security message secret before being inserted, so that the process of transferring information can be done safely. The results of this study steganography techniques can be used in sound. By inserting a text message that is first encrypted and then entered into sound by the Least Significant Bit method.
РОЛЬ МАРКЕРА КОСТНОГО РЕМОДЕЛИРОВАНИЯ ОСТЕОКАЛЬЦИНА В РЕГУЛЯЦИИ ЭНЕРГЕТИЧЕСКОГО ГОМЕОСТАЗА ПРИ САХАРНОМ ДИАБЕТЕ 2 ТИПА
Authors: Ковальчук А. В.  , Зиныч О. В.  , Корпачев В. В.  , Кушнарева Н. Н.  , Прибила О. В.
Published: July 2020

Osteocalcin (OK) is actively involved in the humoral regulation of energy homeostasis. However, the relationship between the level of OK as a modulator of metabolic processes and constitutional and metabolic features in patients with type 2 diabetes mellitus (DM) of a different gender remains not thoroughly studied.The study included 127 patients with type 2 diabetes ≥ 50 years of age. Of these, 70 were postmenopausal women and 57 men.It was found that in the general group of women, the concentration of OK in the blood serum was significantly higher than in men. The observed difference is due to significantly higher levels of OK in women of the older age group (≥ 60 years) in comparison with men. At the same time, a decrease in bone mineral density (BMD) in the femoral neck was observed in subgroups of men and women aged ≥ 60 years and older, while in the younger subgroups of patients, the BMD of lumbar and femoral zones were close to each other.The relationships between OK levels and adipose tissue parameters, evaluated by calculating the morphological and functional index of visceral obesity (IVO), were investigated. An increase in the OK level in the groups of men and women was accompanied by a decrease in the IVO values. The highest degree of insulin resistance was determined in groups of patients with minimal levels of OK and high IVO, and the lowest values were recorded in patients with high levels of OK and low IVO.The decrease of the blood OK level in patients with type 2 diabetes occurs in parallel with an increase in the degree of insulin resistance and dysfunction of visceral adipose tissue. In this case, IVO is a more accurate parameter reflecting the constitutional and metabolic phenotypic changes, compared with the index of the waist circumference. The decrease in BMD in patients with type 2 diabetes is the result of predominantly involutive processes that are noticeable at the age of ≥ 60 years and occur against the background of a decrease in the content of OK with age.
ДОСВІД РОЗВИНУТИХ КРАЇН ІЗ ЗАЛУЧЕННЯ ФАРМАЦЕВТІВ І ПРОВІЗОРІВ ДО ПРОФІЛАКТИКИ ТА ЛІКУВАННЯ ЦУКРОВОГО ДІАБЕТУ
Authors: Білан О. А.  , Кухар О. О.  , Новикова Л. Г.
Published: July 2020

The prevalence of diabetes mellitus (DM) in the world in general, and in Ukraine in particular, is increasingly showing signs of an epidemic. This chronic disease contributes significantly to increased spending on health care services due to severe complications, loss of capacity to work and increased mortality. Medical specialists see a way out of the crisis as providing patients with the opportunity to manage their disease on their own — in partnership with pharmaceutical specialists, namely, clinical care providers. Traditionally, the role of the pharmacist has been focused on delivering medicines and advising patients on medication, but recently, pharmaceutical professionals have started to become more involved in the management system of type I and type II DM by providing pharmaceutical care (PhС) to patients, thus optimizing treatment, improving clinical outcomes and reducing costs.
ОГЛЯД СУЧАСНИХ ПІДХОДІВ ДО РОЗРОБКИ НАНОЛІКІВ
Authors: Брубейкер І. О.  , Білан О. А.  , Марченко-Толста К. С.
Published: July 2020

The article deals with nanopharmacy, a new medical discipline that combines chemistry, physics and engineering to develop nanoscale systems used in diagnosis and therapy. The use of nanoparticles for the development of new nanodrugs requires a deep understanding not only of the properties of nanomaterials, but also of the pathophysiology of diseases. Nanopharmacy help solve complex problems associated with improving the effectiveness of existing therapeutic agents and the use of nanomaterials in the manufacture of nanodrugs.
Análisis de dominios científicos nacionales en Comunicación (Scopus, 2003-2018)
Authors: Trabadela-Robles Javier , Nuño-Moral María-Victoria , Guerrero-Bote Vicente P. , De-Moya-Anegón Félix
Published: July 2020

Scientific research in the communication field has experienced great growth in recent years. Recent technological changes, as well as the emergence of Web 2.0 and 3.0 and new forms of communication, such as social networks, have led to new and varied studies in the discipline. This paper analyzes the scientific production of the 27 countries with the greatest scientific production in the communication field in the period from 2003 to 2018. The results indicate that: the most productive countries are the USA, UK, and Spain; there is less international collaboration than in other disciplines, but there is a network of European collaboration that is quite dense and has great impact, and another network in Pacific countries (Asia + Oceania), albeit with lower density and impact.

Resumen
En los últimos años la disciplina Comunicación ha experimentado un gran crecimiento en investigación. Los recientes cambios tecnológicos, así como la irrupción de la web 2.0 y 3.0 y nuevas formas de comunicación, como las redes sociales, han propiciado nuevos y variados estudios. En este trabajo se analiza la producción científica de los 27 países con mayor producción científica en Comunicación en el período 2003-2018. Algunos resultados son: los países más productivos son Estados Unidos, Reino Unido y España; y hay menos colaboración internacional que en otras disciplinas, sin embargo, existe una red de colaboración europea bastante densa y de gran impacto, y otra red de menor densidad e impacto de países del Pacífico (Asia + Oceanía).
Méthodes diagnostiques et stratégie thérapeutique des TNE pulmonaires (tumeurs carcinoïdes typiques et atypiques)
Authors: Dansin E.
Published: July 2020

Les carcinoïdes bronchiques typiques ou atypiques sont des tumeurs rares. La prise en charge des formes localisées repose essentiellement sur la chirurgie, et leur pronostic reste bon. Le traitement des formes métastatiques demeure difficile et repose sur un niveau de preuve faible. De nouveaux traitements émergent (évérolimus, lutathérapie), mais leur place respective dans l’algorithme thérapeutique est à préciser. L’accès à l’expertise et à la recherche clinique via les réseaux RENATEN-TENpath doit être favorisé.
Ventriculoperitoneal shunt infection rates using a standard surgical technique, including topical and intraventricular vancomycin: the Children’s Hospital Oakland experience
Authors: Raygor Kunal P. , Oh Taemin , Hwang Joan Y. , Phelps Ryan R. L. , Ghoussaini Kristen , Wong Patrick , Silvers Rebecca , Ostling Lauren R. , Sun Peter P.
Published: July 2020

OBJECTIVE

Ventriculoperitoneal (VP) shunt infections are common complications after shunt operations. Despite the use of intravenous antibiotics, the incidence of infections remains high. Though antibiotic-impregnated catheters (AICs) are commonly used, another method of infection prophylaxis is the use of intraventricular (IVT) antibiotics. The authors describe their single-institution experience with a standard shunt protocol utilizing prophylactic IVT and topical vancomycin administration and report the incidence of pediatric shunt infections.

METHODS

Three hundred two patients undergoing VP shunt procedures with IVT and topical vancomycin between 2006 and 2016 were included. Patients were excluded if their age at surgery was greater than 18 years. Shunt operations were performed at a single institution following a standard shunt protocol implementing IVT and topical vancomycin. No AICs were used. Clinical data were retrospectively collected from the electronic health records.

RESULTS

Over the 11-year study period, 593 VP shunt operations were performed with IVT and topical vancomycin, and a total of 19 infections occurred (incidence 3.2% per procedure). The majority of infections (n = 10, 52.6%) were caused by Staphylococcus epidermidis. The median time to shunt infection was 3.7 weeks. On multivariate analysis, the presence of a CSF leak (OR 31.5 [95% CI 8.8–112.6]) and age less than 6 months (OR 3.6 [95% CI 1.2–10.7]) were statistically significantly associated with the development of a shunt infection. A post hoc analysis comparing infection rates after procedures that adhered to the shunt protocol and those that did not administer IVT and topical vancomycin, plus historical controls, revealed a difference in infection rates (3.2% vs 6.9%, p = 0.03).

CONCLUSIONS

The use of a standardized shunt operation technique that includes IVT and topical vancomycin is associated with a total shunt infection incidence of 3.2% per procedure, which compares favorably with the reported rates of shunt infection in the literature. The majority of infections occurred within 2 months of surgery and the most common causative organism was S. epidermidis. Young age (< 6 months) at the time of surgery and the presence of a postoperative CSF leak were statistically significantly associated with postoperative shunt infection on multivariate analysis. The results are hypothesis generating, and the authors propose that IVT and topical administration of vancomycin as part of a standardized shunt operation protocol may be an appropriate option for preventing pediatric shunt infections.
Improving the geological and hydrodynamic model of a carbonate oil object by taking into account the permeability anisotropy parameter
Authors: Martyushev Dmitry
Published: July 2020

Significant share of the developed oil assets related to carbonate complex-built objects has formidably increased in Russia, including the Perm Region. Reliable knowledge of the parameters for the cavern-pore type of the reservoir allows clarifying the existing geological and hydrodynamic models (GHM), selecting a rational development system, regulating the development processes and providing optimal geological and technical measures for this formation. In the construction and adaptation of GHM for oil fields, especially those related to complex-built carbonate reservoirs, knowledge of both horizontal and vertical permeability (anisotropy parameter) is important. When creating GHM of carbonate objects in Perm Region deposits, vertical permeability is often taken to be zero, although this is far from being the case. Determining the vertical permeability (anisotropy parameter), its dynamics when changing the formation and bottomhole pressures and using it in GHM is an urgent task that will improve the quality and reliability of using digital models to calculate and predict the oil production process.

Article describes the methodology for determining permeability anisotropy according to the interpretation of hydrodynamic investigations of wells. Proposed methodology for determining the anisotropy parameter processed the results of more than 200 studies conducted on production and injection wells of the Famennian deposit at the Gagarinskoye field. For each lithological-facies zone, dependence of the permeability anisotropy index on the bottomhole pressure is constructed. To predict and evaluate the effectiveness of the applied geological and technical measures and technological development indicators, author modified the geological and hydrodynamic model taking into account the obtained dependencies on the change in the anisotropy parameter.

Using a modified hydrodynamic model, it was possible to significantly improve the adaptation of both production and injection wells. Thus, the quality and reliability of the digital model of the Famennian deposit at the Gagarinskoye field for calculating and predicting the oil production process has improved.
Geochemical approach in assessing the technogenic impact on soils
Authors: Sarapulova Galina
Published: July 2020

The soil assessment was carried out in the technogenically-affected area of Irkutsk Oblast with the geochemical approach as a key geoecological method using physical and chemical techniques of analysis and ecodiagnostics. Diagnostic signs of the disturbed natural properties of the soil were revealed up to a depth of 40 cm in the profile based on macro- and micromorphometric parameters. The content of heavy metals (HM) – Pb, Zn, Hg, and Cu with an excess of standards was determined, and empirical HM – pH correlations were obtained by statistical clustering of the data array. The contributions of additional factors affecting the chemical element distribution in the soil layer were investigated. Significant soil contamination with sulfates and the possibility of implementing the ion-exchange of HM andfor element immobilization were revealed. It was shown that reactions with sulfates and the influence of pH, HM exchange processes involving mobile K and P can determine the nature of the described chemical element distribution in the multi-factor-contaminated technogenic soil. However, the effectiveness of such types of interaction is different for each metal and also depends on the quantitative ratio of substances and soil characteristics, even under a minor change in pH. Two-parameter correlations of HM distribution in sulfate-contaminated soils confirmed the different degrees of involvement of chemical elements in these types of interactions. The results obtained and the identified factors are of applied significance and can be used as the basis for geoecological differentiation of the contaminated soil, as well as for determining local geochemical fields in the technogenesis zone. Areas of advanced research are related to three-dimensional modeling for a more complete study of the cause-and-effect relationships of geochemical parameters.
Chess 4.5’s participation in the Paul Masson Chess Classic Tournament of 1976
Authors: Slate David J.
Published: July 2020

On July 24–25, 1976, the computer program Chess 4.5 participated in the Paul Masson Chess Classic Tournament. The program achieved an impressive result. This article describes my recollection of this event and its aftermath.
Lightning return stroke electromagnetic field and energy at close distance by using 3D FDTD simulation
Authors: Zhang Ziheng , Tian Yangmeng , Wang Caixia , Wang Xin , Tian Yang
Published: July 2020

In this paper, the lightning return stroke electromagnetic field at close distance is calculated by the way of transmission line (TL) model and full-wave three-dimensional electromagnetic field simulation software XFDTD, which is based on finite-difference time-domain (FDTD) method. The evolution of distributions of electric field and magnetic field are summarized in the study. Furthermore, the total electromagnetic field and major components are analyzed to clarify the electromagnetic hazard from lightning electromagnetic pulse (LEMP). Then the temporal and spatial distribution characteristic of Poynting vector of the electromagnetic environment is shown to expound the energy distribution of LEMP at close distance. The results based on the analyses of field strength and Poynting vector show that the distribution of electric field, magnetic field and Poynting vector at close distance is akin to multilayered cylinder, and LEMP in the region characterized by large amplitude, transient behavior and high electromagnetic energy is a potential threat to adjacent electronic equipments. Moreover, engineering basis concerning LEMP protection and electromagnetic compatibility (EMC) design in the region closed to the return stroke point can be provided by the synthetical analysis of LEMP.
Management of Orthostatic Hypotension in Parkinson’s Disease
Authors: Fanciulli Alessandra , Leys Fabian , Falup-Pecurariu Cristian , Thijs Roland , Wenning Gregor K.
Published: July 2020

Orthostatic hypotension (OH) is a common non-motor feature of Parkinson’s disease that may cause unexplained falls, syncope, lightheadedness, cognitive impairment, dyspnea, fatigue, blurred vision, shoulder, neck, or low-back pain upon standing. Blood pressure (BP) measurements supine and after 3 minutes upon standing screen for OH at bedside. The medical history and cardiovascular autonomic function tests ultimately distinguish neurogenic OH, which is due to impaired sympathetic nerve activity, from non-neurogenic causes of OH, such as hypovolemia and BP lowering drugs. The correction of non-neurogenic causes and exacerbating factors, lifestyle changes and non-pharmacological measures are the cornerstone of OH treatment. If these measures fail, pharmacological interventions (sympathomimetic agents and/or fludrocortisone) should be introduced stepwise depending on the severity of symptoms. About 50% of patients with neurogenic OH also suffer from supine and nocturnal hypertension, which should be monitored for with in-office, home and 24 h-ambulatory BP measurements. Behavioral measures help prevent supine hypertension, which is eventually treated with non-pharmacological measures and bedtime administration of short-acting anti-hypertensive drugs in severe cases. If left untreated, OH impacts on activity of daily living and increases the risk of syncope and falls. Supine hypertension is asymptomatic, but often limits an effective treatment of OH, increases the risk of hypertensive emergencies and, combined with OH, facilitates end-organ damage. A timely management of both OH and supine hypertension ameliorates quality of life and prevents short and long-term complications in patients with Parkinson’s disease.
Por el "Bienestar Mundial Bruto" y su redistribución
Authors: Redacción Consejo de
Published: July 2020

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Estimating Herbage Mass on Pastures to Adjust Stocking Rate
Authors: Dubeux Jose , Wallau Marcelo , Vendramini Joao , Silva Liliane , Griffin Jane , DiLorenzo Nicolas , Santos Erick
Published: July 2020

This new 6-page document explains methods to measure forage mass and utilize that information to estimate an adequate stocking rate. Written by Jose Dubeux, Marcelo Wallau, João Vendramini, Liliane Silva, Jane Griffin, Nicolas DiLorenzo, and Erick Santos, and published by the UF/IFAS Agronomy Department, June 2019. https://edis.ifas.ufl.edu/ag434
Recognizing Heat Stress in Dairy Cows
Authors: Toledo Izabella M. , Dahl Geoffrey E.
Published: July 2020

In persistent hot, sunny and humid conditions, cows can become overheated and may not produce as well, or may experience health issues. This two-page fact sheet written by Izabelle Toledo and Geoffrey Dahl and published by the UF/IFAS Department of Animal Sciences lists the signs of heat stress in dairy cows. https://edis.ifas.ufl.edu/an356
Florida Homeowner Herbicide Guide: Considerations, Applications, and Selection
Authors: Marble Chris
Published: July 2020

While some people opt for professional lawn maintenance companies, some homeowners may wish to perform their own landscape pest control in order to save money, to have more control of what is applied, or simply because they enjoy it. This EDIS publication is for Florida gardeners, horticulturalists and homeowners who want to utilize herbicides to control weeds in their landscape. This publication discusses common herbicides available at retail stores and how homeowners can use these them safely and effectively.https://edis.ifas.ufl.edu/ep575

This publication provides information and general management recommendations for a variety of common weed species found throughout Florida. For a species-specific weed identification guide or information on weed control in turfgrass, visit the EDIS Weed Control directory.
Understanding Investment Analysis for Farm Management
Authors: Cruz Julio , Singerman Ariel
Published: July 2020

Investment decisions are among the most important decisions growers make. In many cases, those investments are in capital assets such as establishing a new orchard or purchasing a new piece of equipment. The process for evaluating those investments is called investment analysis or capital budgeting. This 4-page fact sheet written by Julio Cruz and Ariel Singerman and published by the UF/IFAS Food and Resource Economics Department reviews net present value and the internal rate of return, the two main criteria for decision making when evaluating a decision to invest in a capital asset. https://edis.ifas.ufl.edu/fe1060