bluuebunny/crossref_metadata_2025 huggingface dataset:
Na coleção Sophia Jobim: a presença de Rembrandt e a questão da veracidade dos trajes
Authors:   Universidade Estadual do Rio de Janeiro, Almeida Graciana
Published: May 2023

O presente artigo surgiu ao longo de leituras dos escritos de Sophia Jobim (1904-1968), atualmente conservado no Museu Histórico Nacional (MHN), no Rio de Janeiro. Professora de indumentária histórica da Escola Nacional de Belas Artes (ENBA) a partir de 1949, Sophia deixou um importante material didático, literário e visual capaz de fornecer importantes subsídios para uma investigação crítica referentes ao vestuário e à história da arte. Sua extrema curiosidade levou-a pesquisar em vários museus e escolas especializadas da Europa, da América e da Ásia, como: South Kensington Museun em Londres, Carnavelet em Paris, Metroplolitan Museu em Nova York, Museu Benaki em Atenas; por falta de Museus e de Bibliotecas especializadas no âmbito brasileiro - foram quase trinta anos de pesquisas.
Os desenhos de Raphael Domingues para além do ateliê do engenho de dentro
Authors:   Universidade de São Paulo, Espada Heloisa
Published: May 2023

Esta comunicação tem por objetivo apresentar o processo de pesquisa e os resultados envolvidos na seleção de obras do desenhista Raphael Domingues (1912 – 1979) para a exposição Raphael e Emygdio: dois modernos no Engenho de Dentro, em cartaz no Instituto Moreira Salles do Rio de Janeiro, entre 15 de julho e 7 de outubro de 2012, com curadoria de Heloisa Espada e Rodrigo Naves. Concentrei-me na seleção e análise das obras de Raphael Domingues, enquanto o Rodrigo Naves se dedicou às pinturas de Emygdio de Barros.
A imagem da família Madruzzo nas medalhas e seus usos políticos no século XVI
Authors:   Universidade Estadual de Campinas, Hargrave Isabel
Published: May 2023

Em 1545 ocorria a abertura do aguardado Concílio de Trento. Esse evento, que distorceria a intenção de reforma moral e disciplinar da Igreja Católica há muito perseguida por diversos eclesiásticos e políticos, em direção a uma profunda e rigorosa reforma dos assuntos da fé – como uma reação intensa às postulações protestantes que já ganhavam força e apoio no norte europeu – seria chamada de “l’Iliade del nostro secolo” (a Ilíada de nosso século), por Fra’ Paolo Sarpi, em sua Istoria del concilio tridentino (PROSPERI, 1994: 36).
As Santanas da antiga vila de Santa Ana e Santo Antônio do Tucano
Authors:   Instituto de Educação, Ciência e Tecnologia da Bahia, Santos Jadilson Pimentel dos
Published: May 2023

A cidade do Tucano - Bahia, cujo topônimo, no passado, era Imperial Vila do Tucano guarda em sua Igreja Matriz raro tesouro da arte sacra barroca: uma imagem de Santa Ana Mestra. Esculpida em madeira policromada, por mãos de artistas baianos, foi encomendada em Salvador. Além da imagem, a Igreja de Santa Ana também possui dois painéis de valor histórico considerável: uma pintura de teto, de pequena proporção, também com Santana Mestra, e um painel azulejar incrustado no frontão da Matriz, cuja autoria é do mestre da arte da cerâmica radicado na Bahia, na década de 1950: Udo Knoff. Baseado em fotografias, nas obras artísticas encontradas nessa igreja, e em cartas e documentos, esse trabalho pretende analisar a iconografia de Santa Ana, lançando luzes sobre essa questão comparando-a, revelando-a e divulgando-a, essa que é uma das poucas obras que conta a memória das gentes dos sertões e do empreendimento missioneiro do frei italiano Apolônio de Todi, bem como divulgar o legado material da cidade de Tucano de modo a chamar a atenção no que concerne a proteção desse patrimônio que se encontra ameaçado.
O Curupira e a ninfa selvagem: pintura e identidade amazônica dos anos 20
Authors:   Universidade Federal do Pará, Silva Neto João Augusto da
Published: May 2023

No ano de 1919, chegava ao Rio de Janeiro o pintor Manoel Santiago (1897-1987). A viagem à Capital da República fora para almejar uma formação artística num dos mais importantes centros artístico do país até então: a Escola Nacional de Belas Artes. Amazonense de Manaus, o jovem pintor vinha de Belém do Pará onde tinha trânsito entre artistas de certa projeção no mundo das artes na cidade. Em solo paraense, foi durante as aulas no atelier de seu mestre Theodoro Braga (1872-1953) e nas visitas ao Museu Paraense Emílio Goeldi que o amazonense tomou gosto pela pintura da flora e da fauna locais e dos elementos da arte decorativa indígena.
O tratamento das obras de arte sobre papel de Geraldo Queiroz pertencentes ao acervo do arquivo público de Uberlândia
Authors:   Universidade Federal de Uberlândia, Traldi Juliana Pavesi Miguel
Published: May 2023

Este artigo apresenta o estágio atual da pesquisa de mestrado que está sendo desenvolvida no programa de pós-graduação em Artes da Universidade Federal de Uberlândia, na qual abordamos o processo de tratamento das obras em papel do artista plástico uberlandense Geraldo Queiroz (1916-1958), que constituem um importante acervo no Arquivo Público de Uberlândia. Para tanto, permearemos nos campos conceituais no que se refere à conservação e restauro do suporte papel tendo, como pano de fundo, importantes princípios como os da tradicional escola italiana ou os fundamentos inovadores da escola norte-americana.
Artistas brasileiros e a arte decorativa na Esposizione internazionale dell’industria e del lavoro de 1911
Authors:   Universidade de São Paulo, Amancio Kleber Antonio de Oliveira
Published: May 2023

Esse artigo nasce de minha pesquisa de doutorado. Estudo a vida e a obra do pintor carioca da bellé époque Arthur Timotheo da Costa. Assim como vários artistas de seu tempo, dedicouse, dentre outras matérias, à pintura decorativa. Nesse momento há um notável crescimento na produção dessa forma de expressão artística (VALLE, 2007). Coetâneo a isso estava em curso um processo de aburguesamento intensivo da paisagem carioca (SEVCENKO, 2003: 47). Muitas edificações são demolidas; vivenciava-se a demanda por renovação e o aferro às coisas modernas (CHALHOUB, 1996). Arthur Timotheo realizou vários projetos nessa linha. Trabalhava ora em edifícios públicos, ora para particulares.
Uma breve comparação entre a associação da mulher com a morte em duas obras alemãs do século XVI
Authors:   Universidade Estadual de Campinas, Santos Letícia Roberto dos
Published: May 2023

No território que hoje compreendemos como Alemanha eclodia uma grande efervescência cultural no começo do século XVI, que teve dentre os acontecimentos a Reforma Protestante, desencadeada pela divulgação das 95 teses de Martinho Lutero. Segundo Jean Delumau no livro “A Reforma”, a Reforma foi uma resposta religiosa à grande angustia do fim da Idade Média, quando houve uma série de acontecimentos catastróficos sacudiram e desorientaram as almas, como por exemplo a Peste Negra, o Cisma do Oriente e fomes frequentes. Esse período é caracterizado como de insegurança e sentimento de efemeridade da vida que e refletiu-se em parte nas expressões artísticas, em especial nas artes visuais. Pinturas, gravuras e esculturas com os temas do Juízo Final e da morte proliferam-se nessa época pela Europa. A Alemanha destaca-se nessa época por ter dois dos mais macabros pintores da Europa: Albretch Dürer e Hans Baldung Grien. Ambos são conhecidos pelas suas notaveis pinturas que evocam o Juízo Final e as pinturas com a temática da morte. Na pintura “A Morte e a Donzela”[1] de Baldung Grien e na gravura “Jovem mulher atacada pela Morte ou O raptor”[2] a morte aparece na forma de monstro, de certa forma “atacando” a mulher. Chama a atenção a forma sensual que a morte é retratada, uma voluptuosidade que contrasta com o horror demonstrado pelos rostos das mulheres que são tocadas por ela. A apresentação versará sobre como deu-se a associação pictórica entre a mulher e a morte e como as duas obras supracitadas se aproximam e se diferenciam.
Flávio Império: desenho de um percurso. Apresentação das contribuições do artista para a renovação do espaço cênico paulistano
Authors:   Universidade Estadual de Campinas, Garcia Lívia Loureiro
Published: May 2023

Esta comunicação visa compreender as motivações e o contexto histórico cultural da concepção cenográfica de trabalhos de Flávio Império (1935-1985). Para tanto foram lidos os escritos autográficos do artista e analisados documentos iconográficos (fotografias e desenhos) de cenografias produzidas entre 1956 e 1985.
A Curadoria como História da Arte: aspectos da escrita da História da Arte em Belo Horizonte
Authors:   Universidade Federal de Minas Gerais, Vivas Rodrigo
Published: May 2023

Um dos problemas fundamentais que acompanham a pesquisa em História da Arte e também da História é a construção da narrativa. Como organizar, selecionar um conjunto de fatos relevantes e transformá-los em uma escrita coerente? Existem inúmeras formas de “escrever” a História da Arte e vários caminhos de pesquisa. Gostaria de tratar de um específico: as narrativas elaboradas a partir de exposições ou curadorias. Para tanto, selecionei exposições que foram fundamentais para a construção da História da Arte em Belo Horizonte. É possível afirmar que a escrita da História da Arte de Belo Horizonte é indissociável da dinâmica curatorial. Como a delimitação que desejo trabalhar é anterior a própria noção de curadoria, usarei o termo “curadoria” para experiências recentes e “exposições” para as mais remotas.
Mapeamento mobile art: propostas poéticas e telefones celulares: aspectos históricos e curatoriais em novas mídias
Authors:   Universidade Estadual Paulista, Conceição Rosângela Aparecida da
Published: May 2023

No âmbito da arte e tecnologia, entre os anos de 2003 a 2006, a elaboração de oficinas para difusão da arte combinada aos meios digitais, vinculadas ao Programa Telecentros, da Prefeitura do Município de São Paulo, além da organização de cursos e palestras na Rede SESC São Paulo, desde 2005, permitiram a formação do repertório sobre os meios digitais e as novas configurações do mundo arte, utilizado de modo instrumental nesta pesquisa
Ideias desenhadas: imagens da construção de um artista do lápis
Authors:   Universidade Estadual de Campinas, Silva Rosangela de Jesus
Published: May 2023

O aspecto mais destacado na obra de Angelo Agostini foram seus desenhos, publicados nas diversas revistas pelas quais passou, não apenas para quem lia, mas, conforme citação acima, pelo próprio caricaturista. A força expressiva dessas imagens e o pioneirismo do caricaturista não deixa de trazer inquietações e algumas risadas a quem folheia seu trabalho. Através do sfumato do seu lápis Agostini circulou pelo Brasil na segunda metade do século XIX promovendo debates, denunciando mazelas sociais, imortalizando rostos, satirizando, ironizando, mas acima de tudo, apostando na força de suas imagens enquanto elemento civilizador.
Development and Validation of Career and Employment Competency Scale for Improving Extracurricular Program: Focused on Career and Employment Support Extracurricular Programs at D University
Authors:   The Association of Korea Counseling Psychology Education Welfare, LEE Soon-Hwa , JANG Hye-Jung , KIM Bo-Seong
Published: May 2023

The purpose of this study is to develop a career and employment competency scale andverify its validity to improve the career and employment support extracurricular program at DUniversity. To this end, preliminary questions were extracted through literature review, openquestionnaire responses, and interviews for practitioners of the extracurricular program, and 60preliminary questions were developed through content validity verification. After that, the firstsurvey was conducted on D University students, and item analysis and exploratory factoranalysis were conducted on 556 survey response data. As a result, a scale of 38 questions wasdeveloped for five factors (career and job search, career design, job search skills, practical skills,and career collaboration). To validate the developed scale, a confirmatory factor analysis of 561students from D University showed that the model fit was good, and the final scale wascompleted by confirming the validity of the criteria through the DEU-GRIT career adaptationscale. Based on this, the significance of this study and how to use it to improve theextracurricular program of career and employment were discussed.
A Literature Review for Conducting Systematic Dose-Response Effect Studies on Mindfulness Meditation
Authors:   The Association of Korea Counseling Psychology Education Welfare, CHO Eun-Yi , SHIN Seo-Won
Published: May 2023

The purpose of this literature review is to suggest various considerations for conductingsystematic dose-response effect studies on mindfulness meditation. To that end, we examinedprevious dose-response effect studies on mindfulness meditation using experimental designs. Next, other dose-response effect studies in adjunct fields such as pharmacy, sport science, andcounseling were also investigated to compare similarities and differences. As a result, variousconsiderations and guidelines such as stipulating side effects and manipulating interventionhours were found. Based on the findings, future directions of dose-response effect studies onmindfulness meditation were discussed.
The Impact of PostBereavement Grief on Posttraumatic Growth: Focusing on the Dual Mediating Effect of Social Connectedness and Mindfulness
Authors:   The Association of Korea Counseling Psychology Education Welfare, KIM Du-Gil , SHIN Jae-Han
Published: May 2023

This study attempted to verify the dual mediating effect of social connectedness andmindfulness in the relationship between grief after bereavement and posttraumatic growth forthose who have experienced bereavement. To this end, an online survey was conducted fromDecember 4, 2021 to January 10, 2022, and 304 of them were used as final analysis data. Asa result of the study, first, grief, social bonding, and attention have been shown to have asignificant impact on posttraumatic growth. It can be seen that the higher the level of grief,social bonding, and attention, the higher the posttraumatic growth. Second, in the relationshipbetween mourning after bereavement and posttraumatic growth, social connectedness andmindfulness showed not only a simple mediating effect but also a double mediating effect. Itcan be seen that it may be more effective to analyze personal and social variables in therelationship between grief after bereavement and posttraumatic growth. Based on these researchresults, the significance and limitations of the study were discussed.
Occurrence of microplastics derived from tyres in bottom sediments of Guanabara Bay, Brazil: a form of pollution that is neglected or difficult to detect?
Authors: Baptista Neto José Antônio , Gaylarde Christine C. , de Carvalho Diego G. , Lourenço Marcos F. P. , da Fonseca Estefan M.
Published: May 2023

Aim: Tyre wear particles (TWPs) have been indicated as one of the main sources of microplastics (MPs) in aquatic environments, yet they receive little attention in the published literature. They have never been reported in Guanabara Bay in spite of several published analyses of the abundance, distribution, type, chemical composition and color of MPs in this area. We aimed to develop a method to allow ready detection of these particles in sediments. Methods: Nine sediment samples were taken from locations over a wide geographic cover of the bay. They were collected from different depths using a Van Veen grab sampler. MPs were separated using peroxide degradation of organic matter followed by floatation and filtration. TWPs were identified using a binocular stereo microscope,Scanning Electron Microscopy (SEM) and Fourier transformed infrared spectroscopy. Results: The combined use of these MP detection methods allowed the visualization and identification of high numbers of TWPs in the bay. Exact quantification was impossible because of the large size range of the particles and the use of a sedimentation system already shown to be sub-optimal. Conclusion: High levels of TWPs were detected in Guanabara Bay sediments. Future studies to quantify these particles in coastal environments will necessitate the development of more robust methods, possibly using specific TWP markers. Various options are discussed.
New Antibacterial Diterpenoids from the South China Sea Soft Coral Klyxum molle
Authors: Yu Jia-Dong , Yu Dan-Dan , Su Ming-Zhi , Gu Yu-Cheng , Wang Hong , Guo Yue-Wei
Published: May 2023

Fifteen new diterpenoids, namely xishaklyanes A-O (1-15), along with three known related ones (16-18), were isolated from the soft coral Klyxum molle collected from Xisha Islands, South China Sea. The stereochemistry of the new compounds were elucidated by a combination of detailed spectroscopic analyses, chemical syntheses, quantum chemical calculations and comparison with the reported data. The absolute configuration of compound 18 was established by the modified Mosher's method for the first time. In bioassay, some of these compounds exhibited considerable antibacterial activities on fish pathogenic bacteria, and compound 4 showed the most effective activity with MIC of 0.225 g/mL against Lactococcus garvieae.
Multiscale Modelling of Milk Proteins Adsorption on Metallic Iron Surfaces
Authors: Mosaddeghi Amini Parinaz , Subbotina Julia , Lobaskin Vladimir
Published: May 2023

Food processing and consumption involves multiple contacts between biological fluids and solid materials of processing devices of which steel is one of the most common. Due to complexity of these interactions, it is difficult to identify the main control factors in the formation of undesirable deposits on the device surfaces that may affect safety and efficiency of the processes. Mechanistic understanding of biomolecule-metal interactions involving food proteins could improve management of these pertinent industrial processes and consumer safety in food industry and beyond. In this work, we perform a multiscale study of formation of protein corona on iron surfaces and nanoparticles in contact with cow milk proteins. By calculating the binding energies of proteins with the substrate we quantify the adsorption strength and rank proteins by the adsorption affinity. We use a multiscale method involving all-atom and coarse-grained simulations as well as generation of 3D structures of the proteins for this purpose. Finally, using the adsorption energy results, we predict the composition of protein corona on iron nanoparticles and flat surfaces via a competitive adsorption model.
Pengenalan Media Pemasaran Online Bersama Pemudi pada Usaha Anyaman di Desa Gundik, Slahung, Ponorogo
Authors: Hofifah Siti , Yunita Ratna
Published: May 2023

Now, information technology is growing rapidly in all fields, including business. Information technology has many benefits, for instance, in marketing activities. Product marketing can utilize information technology such as social media (Instagram) and e-commerce (Shopee). By utilizing social media and e-commerce, the products marketed will be known to the wider community. Marketing is one of the keys to success in maintaining the running of the business and competing with manufacturers of similar products. Woven crafts in Gundik Village, Slahung, Ponorogo are small and medium-sized enterprises. Marketing of these woven craft products is still limited to the surrounding Ponorogo area and is marketed through shops and word of mouth. Therefore, the sales in this business are still small, and many people do not know about this woven craft product yet. Besides, there are many people around this business, for example, the youth community, who have a lot of free time. This community service aims to develop the marketing of the woven craft business and provide knowledge about online marketing media to the youth community so that their daily activities are more productive and they make good use of their free time. The method used in this service was the Asset-based Community Development (ABCD) approach by introducing Instagram social media and e-commerce as product marketing media. As a result, this community service, which focuses on introducing online marketing media to develop the woven craft business and youth community during the introduction process and after the introduction process, has a positive impact.
STRATEGI PEMASARAN DAN LITERASI SYARIAH DALAM MENDUKUNG PEMBERDAYAAN UMKM MASYARAKAT
Authors: Fitriani Ajeng Pipit , Aldzu Pazeroma  , Dwi Rahayu
Published: May 2023

Broto Village is one of the villages in Slahung sub-district, Ponorogo district that has many village assets that have the potential to be developed, especially small snack food processing industries such as processed bananas, corn and family medicine (TOGA). The products of small industries that can be marketed today are sale of bananas, banana chips, corn marning, and various processed herbal medicine TOGA. However, it is very unfortunate that the sales of various processed snacks have not been maximized, due to the lack of marketing strategies both in terms of packaging and in terms of promotion. This is due to the lack of ability of Small and Medium Enterprize (UMKM) actors in terms of branding, packaging, and promotions both offline and online. Departing from the assets of the Small and Medium Enterprize (UMKM) actors who already have this small business, this management seminar and marketing strategy is feasible to carry out. In the implementation of the seminar, the enthusiasm of Small and Medium Enterprize (UMKM) actors was extraordinary. They participated in seminar activities from beginning to end. After the seminar, Small and Medium Enterprize (UMKM) actors also tried to apply the knowledge they had gained, by improving branding, packaging, starting to promote their products through social media and recording sales in the cash book. The results of the evaluation show the ability of Small and Medium Enterprize (UMKM) actors to increase. And, of course, a comprehensive evaluation and ongoing assistance will be needed in the future.
MITIGASI RISIKO PEMBIAYAAN KREDIT USAHA RAKYAT (KUR) DI BANK SYARIAH INDONESIA (BSI) KANTOR CABANG PEMBANTU (KCP) JOMBANG PLOSO DALAM MEWUJUDKAN PEMBIAYAAN YANG SEHAT
Authors: Muhammad Miftahul Huda  , Ratna Yunita
Published: May 2023

Abstract: As an effort to minimize the existence of problematic KUR financing, Bank Syariah Indonesia KCP implements risk mitigation. However, in implementing risk mitigation, KUR financing has not been effective, as evidenced by the existence of problematic financing in the KUR financing. The purpose of the study was to determine risk mitigation during the KUR financing procedure, to find out the mitigation of the causes of problematic KUR financing, and the solutions taken in dealing with problematic KUR financing. This study uses a qualitative approach with data collection through interviews and observations. Based on the results of the study, it was concluded that the risk mitigation of KUR financing procedures carried out by Bank Syariah Indonesia KCP Jombang Ploso was in the form of rating methods, financing portfolio management, collateral, cash flow monitoring, recovery management and insurance. Mitigation of risks to the causes of financing problems by training micro staff and providing rescheduling options. Meanwhile, the solution taken by Bank Syariah Indonesia KCP Jombang Ploso for KUR financing is problematic with rescheduling and execution.

Keywords: Risk Mitigation, People's Business Credit, Financing Risk.

 

Abstrak: Sebagai upaya dalam meminamilisir adanya pembiayaan KUR bermasalah, Bank Syariah Indonesia KCP melakukan penerapan mitigasi risiko. Tetapi, dalam melakukan penerapan mitigasi risiko pembiayaan KUR belum efektif, dibuktikan dengan adanya pembiayaan yang bermasalah pada pembiayaan KUR tersebut. Tujuan dari penelitian adalah untuk mengetahui mitigasi risiko pada saat prosedur pembiayaan KUR, mengetahui mitigasi terhadap penyebab pembiayaan KUR bermasalah, dan solusi yang diambil dalam menangani pembiayaan KUR yang bermasalah. Penelitian ini menggunakan pendekatan kualitatif dengan  Pengumpulan data melalui wawancara dan observasi. Berdasarkan hasil penelitian disimpulkan bahwa mitigasi risiko terhadap prosedur pembiayaan KUR yang dilakukan oleh Bank Syariah Indonesia KCP Jombang Ploso berupa metode pemeringkatan, manajemen portofolio pembiayaan, agunan, pengawasan arus kas, manajemen pemulihan dan asuransi. Mitigasi risiko terhadap penyebab pembiayaan bermasalah dengan pelatihan micro staff dan pemberian opsi rescheduling. Sedangkan solusi yang diambil oleh Bank Syariah Indonesia KCP Jombang Ploso terhadap pembiayaan KUR yang bermasalah dengan rescheduling dan eksekusi.

Kata Kunci: Mitigasi Risiko, Kredit Usaha Rakyat, Resiko Pembiayaan.
Efektivitas Pendistribusian Zakat, Infaq, dan Shadaqah pada Masa Pandemi COVID-19 di BAZNAS Kabupaten Ngawi
Authors: Kahfi Rayyan Ashhabul , Futaqi Faruq Ahmad
Published: May 2023

This study aims to find out how the mechanism for distributing zakat infaq and shadaqah and the obstacles during the Covid-19 pandemic in Baznas Ngawi district. The type of research used by the researcher is field research using a qualitative approach. The data used are primary and secondary data by collecting observation data, interviews, and documentation. The results of this study are in the distribution of BAZNAS Ngawi Regency more towards consumptive Constraints faced by the Ngawi Regency BAZNAS institution, namely there are many overlapping points in the distribution of assistance to the community. The effectiveness of BAZNAS in Ngawi Regency is quite good or effective, although there are still shortcomings from BAZNAS because the time for giving Zakat, Infaq and Shadaqah funds does not go directly to the community but is only entrusted to the management who asks for help.

Penelitian ini bertujuan untuk mengetahui bagaimana mekanisme pendistribusian zakat infaq dan shadaqah dan kendala di masa pandemi Covid-19 di Baznas kabupaten Ngawi. Jenis penelitian yang digunakan oleh peneliti adalah penelitian lapangan (field research) dengan menggunakan pendekatan kualitatif. Data yang digunakan yaitu data primer dan sekuknder dengan cara mengumpulkan data observasi, wawancara, dan dokumentasi. Hasil penelitian ini adalah dalam pendistribusian BAZNAS Kabupaten Ngawi lebih kearah konsumtif Kendala yang di hadapi oleh lembaga BAZNAS Kabupaten Ngawi yaitu banyak terjadi tumpang titik dalam penyaluran bantuan ke masyarakat. Efektivitas BAZNAS Kabupaten Ngawi sudah cukup baik atau efektif walaupun masih ada kekurangan dari pihak BAZNAS karena waktu pemberian bantuan dana Zakat, Infaq dan Shadaqah tidak terjun secara langsung ke masyarakat melainkan hanya dititipkan kepada pengurus yang meminta bantuan.
Analisis Pengelolaan Infak melalui Keterbukaan Informasi pada Mushola Al Barokah Desa Sirnoboyo, Kecamatan Pacitan, Kabupaten Pacitan
Authors: Aji Rangga Ilham Pangestu , Damanuri Aji
Published: May 2023

Pengelolaan infak di Indonesia seiring perkembangan teknologi informasi ikut  mengalami perubahan  dalam pengelolaanya yang semula dilakukan secara tradisional  mulai merambah menggunakan bantuan teknologi didalam pengelolaanya seperti yang telah dilakukan mushola Al Barokah dalam pengelolaannya infak dilakukan secara terbuka dengan memanfaatkan media teknologi dan informasi. Kendala yang dihadapi pengelola Infak dalam menumbuhkan minat dan motivasi di antaranya minat masyarakat untuk Infak masih rendah karena  dipengaruhi oleh tingkat pendapatan yang masih rendah, program Infak yang kurang menarik, pemahaman masyarakat tentang zakat hanya sebatas zakat fitrah. Penelitian ini bertujuan untuk mengetahui Pengelolaan Infak Melalui Keterbukaan Informasi Pada Mushola Al Barokah Desa Sirnoboyo Kecamatan Pacitan Kabupaten Pacitan. Metode penelitian yang digunakan adalah metode kualitatif permasalahan berkenaan dengan proses pengelolaan Infak menggunakan bantuan teknologi informasi dengan sumber data sebanyak tiga orang narasumber memlalui metode wawancara dengan teknik pengumpulan data berupa observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan Pengelolaan keuangan sudah berjalan dengan baik, hal ini ditunjukkan dengan adanya peran aktif jamaah secara langsung dalam kegiatan mushola, namun penggunaan media sosial dan webside baik itu untuk pelaporan keuangan  maupun program-program mushola jarang di perbarui terkait pelaporannya karena kurangnya SDM yang mampu mengelolanya.
Preliminary Protocol for Measuring the Reproducibility and Accuracy of Flow values on Digital PET/CT Systems in [15O]H2O Myocardial Perfusion Imaging Using a Flow Phantom
Authors: Siekkinen Reetta , Partanen Heidi , Kukola Linda , Tolvanen Tuula , Fenwick Andrew , Smith Nadia A. S. , Teräs Mika , Saraste Antti , Teuho Jarmo
Published: May 2023

Background:
Several factors may decrease the accuracy of quantitative PET myocardial perfusion imaging (MPI). It is therefore essential to ensure that myocardial blood flow (MBF) values are reproducible and accurate, and to design systematic protocols for assessing this. Until now, no systematic phantom protocols have been available to assess the technical factors affecting measurement accuracy and reproducibility in MPI.
Materials and Methods:
We implemented a standard measurement protocol, which applies a flow phantom in order to compare image-derived flow values with respect to a ground truth flow value with [15O]H2O MPI performed on both a Discovery MI (DMI-20, GE Healthcare) and a Biograph Vision 600 (Vision-600, Siemens Healthineers) system. Both systems have automatic [15O]H2O radio water generators (Hidex Oy) individually installed, allowing us to also study the differences occurring due to two different bolus delivery systems. To investigate the technical factors contributing to the modelled flow values, we extracted the [15O]H2O bolus profiles, the flow values from the kinetic modeling (Qin and Qout), and finally calculated their differences between test-retest measurements on both systems.
Results:
The input time activity curves (TAC) showed dependency on the bolus injection curves. The measurements performed on the DMI-20 system produced Qin and Qout values equal to each other as well as to the reference flow value across all test-retest measurements. Also, all DMI-20 repeatability differences were below 15 %. The measurements performed on the Vision-600 system showed more variation between Qin and Qout values across test-retest measurements and exceeded the 15 % difference in half (6/12) of the measurements.
Conclusions:
This preliminary study proposes a protocol for measuring the accuracy and reproducibility of flow between different injector and PET systems. Our results suggest that flow values can be reproduced on DMI-20 or Vision-600 systems and with two different injector systems, with less than 15 % error. The most significant factor contributing to the variation was the injected bolus, which directly affects the phantom input TAC. In order to extend the protocol to a multi-center setting, a standardized and repeatable bolus injection protocol needs to be designed.
Biomonitoring PAH levels in domestic kitchens using commonly grown culinary herbs
Authors: Eck-Varanka Bettina , Hubai Katalin , Kováts Nora , Teke Gábor
Published: May 2023

Cooking is a significant source of polycyclic aromatic hydrocarbon (PAH) emissions in indoor environments. A biomonitoring study was carried out in previously selected rural Hungarian kitchens to evaluate cooking-related PAH concentrations in 4 common kitchen vegetables such as basil, parsley, rocket and chives. After 1 month exposure, PAH accumulation pattern in tested plants clearly indicated differences in cooking methods and cooking oils used in the selected households. Use of lard and animal fats in general resulted in the high concentrations of higher molecular weight (5- and 6-ring) PAHs, while olive oil usage could be associated with the emission of 2- and 3-ring PAHs. Culinary herbs, however, accumulated carcinogenic PAHs such as benzo[a]anthracene, benzo[b]fluoranthene and chrysene which might question their safe use.
Association of N-nitrosodimethylamine exposure with cognitive impairment based on the clues of mice and humans
Authors: Liu Wei , Huang Jia , Yan Zhi , Lin Yankui , Huang Guanqin , Chen Xiao , Wang Zhou , Spencer Peter S. , Liu Jianjun
Published: May 2023

N-Nitrosodimethylamine (NDMA) is an environmental and food contaminant, but limited data to concern whether NDMA has adverse effects on the brain. This study first determined the concentration of NDMA in foods from aquaculture markets in Shenzhen, then analyzed the effects on C57BL/6 mice and further evaluated on the urine samples of elderly Chinese residents with normal cognition (NC, n = 144), cognitive decline (CD, n = 116) and mild cognitive impairment (MCI, n = 123). The excessive rate of NDMA in foods was 3.32% (27/813), with a exceeding range of 4.78–131.00 µg/kg. Behavioral tests showed that 60 days treatment of mice with 3 mg/kg NDMA reduced cognitive performance. Cognitive impairment in human was significantly associated with sex, educational levels, length of residence in Shenzhen, household registration, passive smoking, rice, fresh vegetables, bacon products. NDMA was detected in 55.4% (212/383) of urine samples, with a median concentration of 0.23 µg/L (1.20×10− 7 µg/L to 157.39 µg/L). The median concentration for NC, CD and MCI were 0.32µg/L, 0.27µg/L, and 0µg/L, respectively. The urinary NDMA concentration had a strong negative correlation with cognitive impairment (Kendall's Tau-b= -0.89, P = 0.024). The median estimated daily intake (EDI) of NDMA was determined to be 6.63 ng/kg-bw/day. Taken together, there appears to be an association between NDMA and human and murine cognition, which provides a new clue to Alzheimer's disease (AD).
Limb remote ischemic preconditioning on lung protection in patients with thoracoscopic lobectomy: a randomized controlled trial
Authors: Zhang Wenfu , Yang Juan , Zhong Saichun , Li Xiaoling , Yuan Liuqing , Zeng Mingwang , Yang Chao , Chen Jing , Zhang Chuanwu , Zhu Yunyan , Xie Haiyu , Zhong Maolin , Liang Weidong
Published: May 2023

Background
One-lung ventilation (OLV) is often used during lobectomy anesthesia. Inflammation and oxidative stress during OLV can aggravate lung tissue injury, which is an important factor causing postoperative acute lung injury. Studies have confirmed that remote ischemic preconditioning (RIPC) can initiate endogenous protective mechanisms and alleviate injury to target organs. However, whether RIPC has a lung protective effect in patients undergoing lung resection remains unknown. Therefore, this randomized controlled clinical study investigated whether RIPC could reduce OLV-related lung injury, improve intraoperative oxygenation parameters, and induce lung protection in patients with thoracoscopic lobectomy.
Methods
We adopted a single-center, randomized, single-blind clinical controlled trial method and selected 54 patients who underwent inferior lobectomy with OLV and were randomly divided into a preconditioning group (RIPC group) and a blank control group (NC group). The preconditioning group received lower limb RIPC before OLV, while the blank NC group did not receive RIPC. RIPC was used to perform 5 cycles of 5 min ischemia /5 min reperfusion on the opposite lower limb via a limb ischemia preadaptor. Four time points after anesthesia induction (T0), 30 min after single-lung ventilation (T1), 90 min after single-lung ventilation (T2), and 30 min after double-lung ventilation restoration (T3) were used as the data-recording and blood-collection points. The main outcome measure was the oxygenation index (OI), while the secondary outcome measures included Clara cell secreted protein CC16, inflammatory cytokines (IL-6), serum malondialdehyde (MDA), lung-related variables, and length of hospital stay.
Results
There was no significant difference in the OI in the RIPC group compared with the NC group at each time point of T0-T3 (P > 0.05), but in general, the OI value of of the RIPC group at the T1-T3 time points showed an increasing trend compared with that of the NC group. There were significant differences in plasma CC16 levels between T1-T3 (P < 0.05), and the plasma CC16 level in the RIPC group was significantly decreased. IL-6 and MDA levels at T1-T3 were lower than those in the NC group (P < 0.05). However, there were no significant differences in blood pH and pulmonary-related variables (respiratory index (RI), alveolar-arterial oxygen partial pressure (A-aDO2), and arterial-alveolar oxygen partial pressure (a/A ratio)) (P > 0.05), and the length of hospital stay was not significantly different (P > 0.05).
Conclusions
Remote limb ischemic preconditioning can reduce lung injury during lobectomy and can protect lung tissue mainly by reducing the inflammatory and oxidative-stress responses.
Metabolic risk factors of lung damage in coal miners caused by dust
Authors: Ibrayeva Lyazat , Shaukhat Diana , Bacheva Irina , Amanbekova Aigul , Rybalkina Dina , Lee Valentina , Abugalieva Tleuzhan , Beloussov Ivan
Published: May 2023

Background and aim
Finding metabolic risk factors for the development of lung damage in coal miners is one of the research priorities, as long as it can improve understanding of the pathogenesis of the target organs damage development due to occupational dust. Considering that the burden of occupational diseases is significant, there remains a need for these professions, and as there is no etiological treatment, the relevance of such studies is undeniable.
Methods
This research analyzed the intermediates of purine metabolism, RNA, DNA, OMP and acid soluble fractions in the blood plasma of coal miners, depending on the length of service in dusty conditions and the influence of all factors on combined outcomes (diseases).
Results
The median levels of guanine, adenine, hypoxanthine, xanthine and uric acid have a common significant trend with a decrease in median values of underground experience up to 3 years and an increase in the group of 5 or more years’ experience. During the underground experience from 3 to 5 years, the activity of xanthine oxidase increased, catalyzing the oxidation of xanthine to uric acid and then decreased. Statistically significant changes depending on the length of service were found for ASF and RNA.
Conclusions
According to logistic regression data, the underground experience of 7–10 years, RNA and xanthine had a statistically significant effect on the disease's development in coal miners. Longtime underground experience increases the chance of a coal miner developing a combined outcome by 8.6 times. The predictive capability of the presented model was 85.4%.
Mendelian Randomization Rules Out Causation Between Periodontitis and Hand Grip Strength
Authors: Yu Ling , Si Chao , Ye Surong , Xu Jingyu , Ye Zitong , Tang Qian , Yang Luyi
Published: May 2023

Background:
Periodontitis (PD) has been linked to low hand grip strength in previous epidemiological observational studies; however, the results are inconclusive. The purpose of this study was to investigate the causal association of PD with hand grip strength.
Methods:
We performed a two-sample bidirectional Mendelian randomization (MR) analysis using publicly released genome-wide association studies (GWAS) statistics. The inverse-variance weighted (IVW) method was used as the primary analysis. We applied three complementary methods, including weighted median, MR-Egger regression and MR pleiotropy residual sum and outlier (MR-PRESSO) to detect and correct for the effect of horizontal pleiotropy. Due to multiple testing, associations with p values < .016 were considered as statistically significant, and p values ≥ .016 and < .05 were considered as suggestively significant. Besides, a multivariable MR (MVMR) design was carried to adjust for body mass index (BMI) and type 2 diabetes (T2D) as well.
Results:
Generally, PD and one of subtypes-Aggressive Periodontitis (AgP) might not affect the risk of low hand grip strength (beta = 0.117 [-0.064, 0.298], beta = -0.018 [-0.042, 0.006]). However, genetically-elevated risk of Chronic Periodontitis (CP) might cause lower hand grip strength (beta = 0.035, p-value = 0.023) while turning insignificant at Bonferroni correction. Besides, no causal effect of hand grip strength on PD and CP was observed (OR = 0.987 [0.964, 1.009]). MVMR analysis also supported such null associations even after adjusting for BMI and T2D.
Conclusion:
This MR study ruled out the causal relationship between PD and hand grip strength, despite observational studies reporting an association between PD and hand grip strength.
Two novel single-chain variable fragments exert bactericidal activity against Acinetobacter baumannii through destabilization of the outer membrane
Authors: Basardeh Eilnaz , Gavgani Somayeh Piri , Nikbin Vajihe sadat , Nazari Farzaneh , Oghalaie Akbar , Azizi Masoumeh , Sharifzadeh Zahra , Fateh Abolfazl , Rahimi-Jamnani Fatemeh
Published: May 2023

Background Acinetobacter baumannii is notorious for its high levels of resistance and the development of clinically-effective antimicrobial agents seems to be an urgent medical challenge. Bactericidal single-chain variable fragments (scFvs) are novel antibacterial agents capable of inhibiting the growth of pathogens (e.g. Staphylococcus aureus, Pseudomonas aeruginosa, A. baumannii) independently of the host immune system. We previously found that two fully human scFvs, EB211 and EB279, showed direct growth inhibitory activity against A. baumannii strains. In the current study, the antibacterial activity of EB211 and EB279 against A. baumannii, Klebsiella pneumonia, and P. aeruginosa strains was appraised in the presence of a high concentration of magnesium (Mg2+) (20 mM) to find the bactericidal mechanism of these two scFvs. Moreover, epitope mapping and immunoblotting were done to identify A. baumannii proteins targeted by EB211 and EB279.
Results EB211 and EB279 similar to colistin sulfate, lost their activity in the presence of Mg2+, demonstrating that EB211 and EB279 exerted growth inhibitory activity by displacing Mg2+ and interrupting the integrity of the outer membrane. The immunoblotting results also exhibited that EB211 and EB279 bound OprD and TonB family C-terminal domain, respectively.
Conclusions EB211 and EB279 by disruption of the outer membrane A. baumannii elicit direct growth inhibitory activity without the need for immune cells or complements which could be helpful for use in immunocompromised patients.
Development of a Loop-Mediated Isothermal Amplification Assay for Rapid and sensitive Detection of Hemileia vastatrix in Coffee
Authors: Wu Weihuai , Wang Guihua , Wang Han , Gbokie Thomas , He Chunping , Huang Xing , Liang Yanqiong , Li Rui , Yi Kexian
Published: May 2023

Coffee leaf rust (CLR) caused by Hemileia vastatrix is a worldwide devastating disease. Early monitoring is crucial for controlling CLR quickly and efficiently. However, it is difficult to accurately identify CLR at the early stage via naked eye; and the detection of H. vastatrix using PCR-based methods were time-consuming, laborious, and sometimes low- sensitivity. LAMP technology is known for its speed, specificity, and sensitivity to accurately identify many different pathogens. Therefore, in this study, by comparing ITS sequences of H. vastatrix with other H. vastatrix and Uredinales strains using National Center for Biotec- hnology Information (NCBI) by BLASTn, we designed specific primers targeting the unique region and its flanking regions of ITS sequences for H. vastatrix. Using SYBR Green I dye, we established a LAMP technique for rapid and sensitive detection of H. vastatrix. Furthermore, we optimized the LAMP protocol was to enhance both sensitivity and specificity for H. vastatrix detection. Under the optimized condition, the establised LAMP protocol could detect as low as 1pg/μl of H. vastatrix DNA in 60min at 63℃, which is ~100 times more sensitive than conventional PCR. This method can successfully detect H. vastatrix in the early CLR symptom on the coffee leaves in the field.
Immune checkpoint inhibitors combined with radiotherapy/chemoradiotherapy in treating locally advanced or recurrent/metastatic esophageal squamous cell carcinoma: A real-world study
Authors: Zhao Xiao-Han , Gao Hong-mei , Wen Jing-Yuan , Wang He-Song , Wu Luan-ying , Song Chun-Yang , Deng Wen-Zhao , Zhu Shu-Chai , Shen Wen-Bin
Published: May 2023

Objective: This study was designed to investigate the prognostic factors for immune checkpoint inhibitors (ICIs) combined utilization with radiotherapy (RT)/chemoradiotherapy (CRT) and to evaluate their toxicity in locally advanced or recurrent/metastatic esophageal squamous cell carcinoma (LA/RM ESCC).
Methods: In this study, 198 LA/RM ESCC patients who received ICIs combined with RT/CRT in the Department of Radiotherapy of the Fourth Hospital of Hebei Medical University were retrospectively analyzed. Univariate and multivariate analyses were performed to determine the prognostic factors for overall survival (OS) and progression-free survival (PFS). Subgroup analysis was utilized to explore the prognostic factors, the treatment respond and treatment-related adverse events (trAEs) were analyzed.
Results: The median OS and PFS were 30.4 months (95% confidence interval [CI]: 15.1–45.7 months) and 15.3 months (95% CI: 12.8–17.8 months), respectively. The median OS and PFS for patients achieving objective respond (ORR group, including complete response and partial response) were 50.8 months (95% CI: 25.8–75.7 months) and 20.5 months (95% CI: 14.1–27.0), respectively, which were higher than those in non-ORR group (OSnon-ORR:17.5 months, 95% CI: 14.0–21.0; χ2 = 13.881, P < 0.001; PFSnon-ORR: 12.1 months, 95% CI: 10.1–14.1, χ2 = 10.676, P = 0.001). Results from subgroup analysis illustrated combined ICIs with radiotherapy could improve the treatment respond (χ2 = 47.725, P = 0.000). The OS rate (χ2 = 18.836, P < 0.001) and PFS rate (χ2 = 6.881, P = 0.009) were significantly higher in the whole-lesion radiotherapy group than in the partial-lesion radiotherapy group. Multivariate analysis showed that the number of immune cycles, the coverage of radiotherapy target, the modality of ICIs-combination therapy and treatment response were independent prognosis factors for OS (hazard ratio [HR] = 0.512, 2.043, 1.889, and 1.912, respectively; P = 0.001, 0.001, 0.013, and 0.002, respectively). Radiotherapy coverage and treatment response were independent factors for PFS (HR = 1.478 and 1.597, respectively; P = 0.032 and 0.012, respectively). In the entire study population, 83 patients (41.9%) had ≥ grade 2 trAEs.
Conclusions: ICIs combined with radiotherapy/chemoradiotherapy are safe and effective in LA/RM ESCC patients. The addition of radiotherapy could improve the treatment respond and whole-lesion radiotherapy improve prognosis compared with partial-lesion radiotherapy group. The number of immunotherapy cycles and treatment response are the main factors affecting prognosis.