bluuebunny/crossref_metadata_2025 huggingface dataset:
A self-adjoint velocity-stress full-waveform inversion approach to microseismic source estimation
Authors: Kaderli Jordan , McChesney Matthew D. , Minkoff Susan E.
Published: June 2018

Accurate estimation of microseismic events in time and space enables important characterization of hydraulic fracture networks. Determining the orientation of the fracture can help differentiate between reactivation of an in situ fracture and a hydraulically induced fracture, which is important in characterizing the effectiveness of the stimulation process. We consider the source as separable in time and space and invert for a complete description of the source in one of these two dimensions assuming the other is known. We recover the wavelet, which includes the source amplitude and time evolution. In space, we recover a description of the source that is distributed and includes an estimate of the moment tensor at every point in the domain. A change of variables applied to the velocity-stress form of the elastic-wave equation ensures that the system is self-adjoint. Thus, full-waveform inversion can be tailored to estimate microseismic events with limited modifications to the forward wave solver. The inversion does not use any a priori assumptions about the form of the source, does not require a good starting guess for accurate source recovery, and is robust in the presence of noise. Applying this technique to wavelet inversion correctly recovers a 30 Hz Ricker wavelet from a zero initial guess with and without noise. Furthermore, for a realistic microseismic event generated from coupled flow and deformation modeling, the algorithm recovers the peak time and approximate shape of the wavelet. In fact, our algorithm recovers as much of the true wavelet as possible given the energy in the observed data. Furthermore, experiments involving a distributed source in the shape of an ellipse illustrate that the inversion scheme can not only estimate the focal mechanism of failure events, but also the geometry of the failure plane.
Elastic reflection traveltime inversion with decoupled wave equation
Authors: Wang Guanchao , Wang Shangxu , Song Jianyong , Dong Chunhui , Zhang Mingqiang
Published: June 2018

Elastic full-waveform inversion (FWI) updates high-resolution model parameters by minimizing the residuals of multicomponent seismic records between the field and model data. FWI suffers from the potential to converge to local minima and more serious nonlinearity than acoustic FWI mainly due to the absence of low frequencies in seismograms and the extended model domain (P- and S-velocities). Reflection waveform inversion can relax the nonlinearity by relying on the tomographic components, which can be used to update the low-wavenumber components of the model. Hence, we have developed an elastic reflection traveltime inversion (ERTI) approach to update the low-wavenumber component of the velocity models for the P- and S-waves. In our ERTI algorithm, we took the P- and S-wave impedance perturbations as elastic reflectivity to generate reflections and a weighted crosscorrelation as the misfit function. Moreover, considering the higher wavenumbers (lower velocity value) of the S-wave velocity compared with the P-wave case, optimizing the low-wavenumber components for the S-wave velocity is even more crucial in preventing the elastic FWI from converging to local minima. We have evaluated an equivalent decoupled velocity-stress wave equation to ERTI to reduce the coupling effects of different wave modes and to improve the inversion result of ERTI, especially for the S-wave velocity. The subsequent application on the Sigsbee2A model demonstrates that our ERTI method with the decoupled wave equation can efficiently update the low-wavenumber parts of the model and improve the precision of the S-wave velocity.
A practical implementation of subsalt Marchenko imaging with a Gulf of Mexico data set
Authors: Jia Xueyi , Guitton Antoine , Snieder Roel
Published: June 2018

Marchenko redatuming allows one to use surface seismic reflection data to generate the seismic response from sources at the surface to any point in the subsurface. Without requiring much information about the earth’s properties, the seismic response generated by Marchenko redatuming contains accurate estimates of not only the primaries but also the internal multiples. A target-oriented imaging method, referred to as Marchenko imaging, was implemented for imaging complex structures of the earth using the seismic response obtained through Marchenko redatuming. Taking account of the contribution of primaries and internal multiples, Marchenko imaging produces images that contain fewer artifacts than the images obtained using conventional imaging methods (e.g., reverse time migration) with the same input data. In this study, we applied Marchenko imaging to a field data set acquired at the Gulf of Mexico to produce an image of a subsalt area. We investigated two important and practical aspects of the Marchenko framework: (1) the missing near offsets in marine shot records and (2) the calibration of the reflection data. Finally, we suggested a workflow for processing the marine towed-streamer field data set acquired at the Gulf of Mexico, and we have developed a complete theoretical and practical framework to produce a target-oriented subsalt image using the Marchenko methods. The images obtained from Marchenko imaging are consistent and comparable, for the most part, with conventional migration methods. However, Marchenko imaging achieves improvements in the continuity of the geologic structures and in suppressing the artifacts that are caused by internal multiples.
Artifact-free reverse time migration
Authors: Zhang Lele , Slob Evert , van der Neut Joost , Wapenaar Kees
Published: June 2018

We have derived an improved reverse time migration (RTM) scheme to image the medium without artifacts arising from internal multiple reflections. This is based on a revised implementation of Marchenko redatuming using a new time-truncation operator. Because of the new truncation operator, we can use the time-reversed version of the standard wavefield-extrapolation operator as initial estimate for retrieving the upgoing focusing function. Then, the retrieved upgoing focusing function can be used to directly image the medium by correlating it with the standard wavefield-extrapolation operator. This imaging scheme can be seen as an artifact-free RTM scheme with two terms. The first term gives the conventional RTM image with the wrong amplitude and artifacts due to internal multiple reflections. The second term gives a correction image that can be used to correct the amplitude and remove artifacts in the image generated by the first term. We evaluated the success of the method with a 2D numerical example.
From World to Globe: The Transformation of Israeli Cultural Production in the Time of Neoliberal Globalization
Authors: Cohen Kfir
Published: June 2018

This essay examines recent developments in Israeli cultural production. To do so, it argues, we must think of new cultural forms as responses to the neoliberal privatization reforms that accompany globalization. These reforms have altered Israeli social life to the degree that the once peripheral literature and cinema that conformed to Fredric Jameson's definition of Third World national allegories can now be read as symptoms of First World cultural production. This historical and aesthetic shift has made itself felt at the heart of Israeli daily life in the rearticulation of the relation between private and public spheres. Recent Israeli literature and film consequently invite us to rethink the stylistic preoccupation of contemporary theories of world literature by asking how these media use aesthetic figures to give form to the concepts of freedom, necessity, and knowledge. To look at this aesthetic and political shift, I offer a comparative reading of Yeshayahu Koren's 1967 novella, Funeral at Noon, and Adam Sanderson's 2014 cinematic adaptation of that novella.
Romancing the Anthropocene: H. G. Wells and the Genre of the Future
Authors: Rosenberg Aaron
Published: June 2018

This essay considers how the representation of deep time affects, and is affected by, literary genres. It takes The Time Machine (1895) as its case study, investigating the ways in which H. G. Wells's work repurposes the conventions of the romance genre as a means of narrating expansive temporal scales that exceed the representational capacity of the realist novel. The essay's overarching suggestion is that stretching narratives to the extreme longue durée of the geologic epoch necessitates shifting away from realism, opening new possibilities for genres (including melodrama, epic, and, in this case, romance) that the realist tradition had ostensibly superseded. Understanding how the formal expansiveness of literary genres can be mobilized strategically, it concludes, affords a critical perspective for analyzing the Anthropocene—a concept whose narrative and discursive patterns concern the contemporaneity of deep time and the present and that could itself be construed as a genre.
A Tale of Two Materialisms
Authors: Hoyos Héctor
Published: June 2018

New materialist approaches to the novel call into question the hermeneutical value of suspicion and critique. Meanwhile, historical materialism tends to neglect aspects of form, focusing instead on social function. Drawing from Las comidas profundas (1997), by Cuban writer Antonio José Ponte, and Cuban Counterpoint: Tobacco and Sugar (1940, trans. 1995), by anthropologist Fernando Ortiz, the essay charts a third approach, transcultural materialism, that reconciles the two tendencies. Works written in this mode deploy narrative and literary language to articulate labor with nonhuman themes, demonstrating the continuity of phenomena across botanical, economic, and cultural realms. Crucially, literature here serves as the primary means for critical elucidation rather than as the mere illustration of political ecological ideas. The limit case considered in the article—stories from the island of Cuba and its staples of tobacco, sugar, and scarce food—allows for a reconsideration of the role of objects in fiction both as stand-ins for social relations and as agents in their own right. In closing, the essay outlines three principles for a world literature infused with transcultural materialism: contemporaneity, multipolarity, and hospitality.
Modeling Consumer Footprints on Search Engines: An Interplay with Social Media
Authors: Ghose Anindya , Ipeirotis Panagiotis G. , Li Beibei
Published: June 2018

It is now well understood that social media plays an increasingly important role in consumers’ decision making. However, an overload of social media content in product search engines can hinder consumers from efficiently seeking information. We propose a structural econometric model to understand consumers’ preferences and costs on search engines to improve user experience under unstructured social media. Our model combines an optimal stopping framework with an individual-level random utility choice model and analyzes click behavior in conjunction with purchase choices. Our model accounts for three major constraints in a consumer’s decision-making process: (1) interdependency in decision making for different alternatives, (2) sequential arrival of information revealed by click-throughs, and (3) nonnegligible search cost. Our approach allows us to jointly estimate consumers’ heterogeneous preferences and search costs under the interplay of social media and search engines, and to predict search and purchase behavior for each consumer. We validate the model using an individual session-level data set of approximately seven million observations resulting in room bookings in 2,117 U.S. hotels. Interestingly, our analysis allows us to quantify the trade-off between consumers’ benefits and cognitive costs from using large-scale unstructured social media information during decision making. Our policy experiments show that providing a carefully curated digest of social media content during the earlier stages of consumer search (i.e., on the search results summary page) can lead to a 12.01% increase in the overall search engine revenue.

The online appendix is available at https://doi.org/10.1287/mnsc.2017.2991 .

This paper was accepted by Anandhi Bharadwaj, information systems.
Securing funds from businesses
Authors: Best Brin
Published: June 2018

Continuing his recent series of fundraising advice articles, Brin Best looks at how schools should engage with business – both locally and further afield – in order to raise funds and attract other support
The mark of success: Part 5
Authors: Bromley Matt
Published: June 2018

In part five of his seven-part series on effective feedback techniques and practices, Matt Bromley focuses on developing an effective school assessment policy
Tackling sexual harassment
Authors: Cole Anna
Published: June 2018

New government advice on tackling sexual violence and sexual harassment between students has been published. Anna Cole looks at what the guidance says and how schools must now think about implementing it
Objetividad y constitución intersubjetiva
Authors: Candioti María Elena
Published: June 2018

El trabajo analiza el alcance del proyecto husseliano de fundamentar la objetividad del mundo y de la ciencia en la intersubjetividad trascendental. A las dificultades de precisar el sentido de esta intersubjetividad trascendental y cómo comprenderla en relación a la comunidad humana, se suman las tensiones internas de la fenomenología acerca del conocimiento y del lenguaje. La constitución del mundo socio-cultural requiere dar cuenta de los actos comunicativos y de los procesos comprensivos implícitos, y por tanto, dar una respuesta a las posibilidades de convergencia de perspectivas dadas por los diversos “mundos circundantes”. La articulación husserliana en una única comunidad de mónadas fundamentada en el tiempo intersubjetivo y originario, y el recurso a la “univocidad” del significado, no resultan soluciones satisfactorias. Suponen una idea de racionalidad que exige ser revisada, y un replanteo de la idea de significado desde marcos más amplios que los definidos por una filosofía de la conciencia.
Wittgenstein y la ética
Authors: De Zan Julio
Published: June 2018

En Wittgenstein encontramos una intuición muy profunda y una valoración muy elevada del ethos (das Ethische) como lo más importante para la vida. Pero este autor quiere preservar el ethos puro, separado tanto de la pretendida existencia de un mundo ético objetivo (die Sittlichkeit en sentido hegeliano), como del discurso moral. En este artículo se consideran las expresiones de Wittgenstein sobre la ética como ejemplo paradigmático de la ética del bien en cuanto diferente de la moral, de sus temas y características fundamentales, así como de los límites del discurso filosófico con respecto a estas cuestiones profundas del sentido último de la vida, del bien y de la felicidad.
Losing Common Ground: Social Sorting and Polarization
Authors: Mason Lilliana
Published: June 2018

The alignment between partisan and other social identities has generated a rift between Democrats and Republicans that is deeper than any seen in recent American history. Without the cross-cutting identities that have traditionally stabilized the American two-party system, partisans in the American electorate are now seeing each other through prejudiced and intolerant eyes. In this article, partisan social divisions are examined in the 2016 electorate, with an eye to the co-occurrence between these social divisions and contemporaneous resistance to compromise and intolerance of social outgroups. In particular, as Republicans and Democrats grow more socially distinct, they like outgroups less and privilege victory over the national greater good. This effect is particularly visible among Republicans, whose social makeup is particularly homogeneous, even in comparison with Democrats. Some potential solutions are briefly addressed.
Affective Polarization and Ideological Sorting: A Reciprocal, Albeit Weak, Relationship
Authors: Lelkes Yphtach
Published: June 2018

American partisans are far more hostile towards out-party members than they were 40 years ago. While this phenomenon, often called affective polarization, is well-documented, political scientists disagree on its cause. One group of scholars believes that affective polarization is driven by processes related to social identity theory. In particular, cross-cutting identities have declined in America, and toxic political communication continuously primes partisan identities and resentment. Recently, several scholars have pointed to another phenomenon as the root cause of affective polarization: partisan sorting, i.e. the alignment of partisan identities with ideologically consistent issue positions. I review evidence in favor of each claim, and provide additional evidence that affective polarization has increased about as much among those who are not sorted as among those who are sorted. Furthermore, while sorting is only related to affective polarization among the most politically knowledgeable, affective polarization has increased across all levels of political knowledge. Finally, affective polarization may also increase sorting, further complicating any clear cut causal relationship.
Calpionellid biostratigraphy and microfacies of the Upper Tithonian pelagic carbonates in northeastern Serbia (Carpatho–Balkanides)
Authors: Carević Ivana , Taherpour-Khalil-Abad Morteza , Mirković Monika , Jovanović Velimir , Mojtahedin Elham , Vušković Dragana
Published: June 2018

The occurrence of microfossil assemblage represented by calpionellids in close association with benthic foraminifera and encrustingCrescentiella morronensisis reported for the first time from the Upper Tithonian of NE Serbia. The biostratigraphic and sedimentological investigations were carried out on a 250 m thick carbonate succession in Jelenska Stena quarry cropping out along the Danube River Gorge in the border area of Serbian Carpatho–Balkanides and Romanian Southern Carphatians. On the basis of determined benthic foraminiferal taxaTextulariasp. cf.T. bettenstaedtiandEverticyclammina praekelleriin the lower part of the succession and calpionellid association dominated by the representatives of calpionellid generaTintinnopsella, CrassicollariaandCalpionellathe carbonate succession is assigned to the Upper Tithonian. The scarcity of calpionellid zonal species prevents the nominal zones being recognized. Petrographic analysis of thin-sections led to the recognition of three basin microfacies types: bioclastic wackestone, bioclastic peloidal wackestone/packstone and mudstone. These microfacies characterize the SMF 3 and SMF 4 which indicate deposition in slope and toe-of-slope environments. This study extends the palaeogeographical distribution of Upper Tithonian calpionellids along the northern Tethyan margins. The investigated carbonate succession is compared with coeval strata from other northern Tethyan regions.
Overview of tissue kallikrein and kallikrein-related peptidases in breast cancer
Authors: Figueroa Carlos D. , Molina Luis , Bhoola Kanti D. , Ehrenfeld Pamela
Published: June 2018

The kallikrein family comprises tissue kallikrein and 14 kallikrein-related peptidases (KLKs) recognized as a subgroup of secreted trypsin- or chymotrypsin-like serine proteases. KLKs are expressed in many cellular types where they regulate important physiological activities such as semen liquefaction, immune response, neural development, blood pressure, skin desquamation and tooth enamel formation. Tissue kallikrein, the oldest member and kinin-releasing enzyme, and KLK3/PSA, a tumor biomarker for prostate cancer are the most prominent components of the family. Additionally, other KLKs have shown an abnormal expression in neoplasia, particularly in breast cancer. Thus, increased levels of some KLKs may increase extracellular matrix degradation, invasion and metastasis; other KLKs modulate cell growth, survival and angiogenesis. On the contrary, KLKs can also inhibit angiogenesis and produce tumor suppression. However, there is a lack of knowledge on how KLKs are regulated in tumor microenvironment by molecules present at the site, namely cytokines, inflammatory mediators and growth factors. Little is known about the signaling pathways that control expression/secretion of KLKs in breast cancer, and further how activation of PAR receptors may contribute to functional activity in neoplasia. A better understanding of these molecular events will allow us to consider KLKs as relevant therapeutic targets for breast cancer.
Crystal structure of 6-(2-bromoacetamido)tetrahydro-2H-pyran-2,3,4,5-Tetrayl tetraacetate, C16H22BrNO10
Authors: Lin Ping , Nie Xu-Liang , Yin Zhong-Ping , Li Zhong-Chao , Liu Jia , Shang-Guan Xin-Chen , Peng Da-Yong
Published: June 2018

[C16H22BrNO10], orthorhombic, P212121 (no. 19), a = 9.7453(13) Å, b = 9.9023(13) Å, c = 21.885(3) Å, V = 2111.9(5) Å3, Z = 4, R
gt(F) = 0.0357, wR
ref(F
2) = 0.0981, T = 296(2) K.
Populism Is a Distraction
Authors: Nederveen Pieterse Jan
Published: June 2018

Should a discussion of populism be concerned with populism—along with revulsion of its various extremisms (perhaps along with hints of social and psychopathology and hence, implicit endorsement of ‘moderate’ positions)? Or should it rather be concerned with the failure of institutions and the misbehavior of elites in a world in which 8 billionaires own as much as half the world population? Option a) will yield a totally different and probably somewhat more predictable discussion than option b), which may include ‘from bad to worse’. According to option c) different types of populism—including ‘pluto-populism’—should generate different treatments. This discussion follows options b) and c).
Health promotion and prevention in Germany – taking stock of the national situation against the backdrop of the Shanghai declaration
Authors: Grossmann Beate , Höfler Martha
Published: June 2018

The World Health Organisation’s Shanghai Declaration (2016) emphasises the need to promote good governance, healthy cities and health competence in order to facilitate health and sustainability across the globe. This article outlines where Germany currently stands in terms of implementing these health promotion and prevention objectives.
Gesundheitsförderung und Prävention in der Schwangerschaft: BabyCare
Authors: Kirschner Wolf , Dudenhausen Joachim W.
Published: June 2018

Die Schwangerenvorsorge in Deutschland ist vornehmlich risikofaktorenorientiert, und die Prävention der Frühgeburt konzentriert sich auf klinisch-medizinische Maßnahmen der Sekundärprävention. Maßnahmen der Gesundheitsförderung und Primärprävention werden durch das BabyCare Programm etabliert. Diese Maßnahmen müssen deutlich verbreitert werden und zukünftig auch bereits präkonzeptionell ansetzen.
Steuerung sozialraumbezogener Gesundheitsförderung in Kommunen
Authors: Richter-Kornweitz Antje , Kruse Christina
Published: June 2018

Die Gesundheitsförderung in marginalisierten Lebenswelten stellt Kommunen bundesweit vor große Herausforderungen. Der Sozialraum stellt sich innerhalb der Kommunen als wichtiges Setting dar, um vulnerable Gruppen zu erreichen und Gesundheitsförderung strategisch zu verankern. Dafür bedarf es einer entsprechenden Steuerung, die Vernetzung und Beziehungsaufbau ermöglicht sowie Ressourcen bedarfsgerecht bereitstellt.
Utilization of prevention and health promotion among migrants
Authors: Spallek Jacob , Schumann Maria , Zeeb Hajo
Published: June 2018

The uptake of existing preventive and health promotion offers by migrants in Germany is rather heterogeneous, and major information gaps are noted. Current results provide limited evidence that migrants and their children seem to use prevention and health promotion services less frequently than non-migrants. In order to improve access to preventive and other health services for migrants, a combination of migrant-specific and migrant-sensitive approaches seems to be useful.
On the energy dissipative spatial discretization of the barotropic quasi-gasdynamic and compressible Navier–Stokes equations in polar coordinates
Authors: Zlotnik Alexander
Published: June 2018

The barotropic quasi-gasdynamic system of equations in polar coordinates is treated. It can be considered a kinetically motivated parabolic regularization of the compressible Navier–Stokes system involving additional 2nd order terms with a regularizing parameter τ > 0. A potential body force is taken into account. The energy equality is proved ensuring that the total energy is non-increasing in time. This is the crucial physical property. The main result is the construction of symmetric spatial discretization on a non-uniform mesh in a ring such that the property is preserved. The unknown density and velocity are defined on the same mesh whereas the mass flux and the viscous stress tensor are defined on the staggered meshes. Additional difficulties in comparison with the Cartesian coordinates are overcome, and a number of novel elements are implemented to this end, in particular, a self-adjoint and positive definite discretization for the Navier–Stokes viscous stress, special discretizations of the pressure gradient and regularizing terms using enthalpy, non-standard mesh averages for various products of functions, etc. The discretization is also well-balanced.

The main results are valid for τ = 0 as well, i.e., for the barotropic compressible Navier–Stokes system.
5th National Congress of Pharmacoeconomics and Pharmacoepidemiology
Authors: Société Marocaine de l’Economie des Produits de Santé SMEPS
Published: June 2018

Résumés des communications orales et affichées du Vème Congrès National de Pharmacoéconomie et de Pharmacoépidémiologie. 26 – 28 octobre 2017. UM6SS - Casablanca, Maroc.
Estudio epidemiológico de hidatidosis comparando los test de ELISA IgE y Western Blot en población de cinco provincias de la Región Lima. 2015
Authors: Vildozola Gonzales Herman , Roldan Gonzales William , Espinoza Blanco Yrma , Huapaya Herreros Pedro , Jimenez Ramirez Susana , Valenzuela Peña Mercedes , Villar Huamán Cristian
Published: June 2018

Introducción. La aparición de algunas zoonosis en varias provincias de la región Lima en el año 2015, motivó una investigación de diversas zoonosis por la Dirección de Salud de la Región Lima Provincias. Objetivo. Determinar la seroprevalencia de hidatidosis (equinococosis) mediante el test de ELISA IgE comparado con el Western Blot en cinco provincias de la Región Lima. Métodos. Se recolectó un total de 560 muestras de suero de pobladores de cinco provincias de la Región Lima: Canta (n=180), Huaral (n=55), Yauyos (n=133), Cajatambo (n=32), y Huaura (n=160). Se detectaron anticuerpos IgE y anticuerpos IgG mediante el test de ELISA y Western-Blot respectivamente. Resultados. Un total de 39 muestras procedentes de pobladores de las provincias de Canta, Yauyos y Huaura, fueron positivas al test de ELISA IgE (seroprevalencia de 6,96%) y 33 fueron positivas al Western Blot IgG (seroprevalencia de 5,89%), con presencia de bandas débiles de 8 y 16 kDa. Se determinó una concordancia del 99% entre ambos tests, (índice kappa =0,91). El 50% (20/39) de los sujetos seropositivos tuvieron entre 25 y 60 años de edad, mientras que la menor proporción de seropositivos (1/39) fueron niños menores de cinco años. Conclusiones: El test de ELISA IgE puede ser utilizado para la detección de individuos seropositivos a anticuerpos anti Echinoccocus spp., mostrando alta concordancia con el Western Blot IgG. Podría utilizarse esta técnica en estudios seroepidemiológicos de campo.
Guía de práctica clínica para el diagnóstico y tratamiento de hemofilia en el Seguro Social de Salud del Perú (EsSalud)
Authors: Mendoza Ordoñez Saúl , Loayza Urcia Nancy , Trujillo Cerna Maribel , Herrera Cunti Celina , Yanac Avila Rommel , Ormeño Apaza Walter , Delgado Silva Carlos , Díaz Robles David , Hernández Adrián V. , Piscoya Alejandro , Suárez Moreno Víctor , Timaná-Ruiz Raúl
Published: June 2018

Introducción. La hemofilia es un trastorno hemorrágico congénito poco común que requiere un manejo interdisciplinario, complejo, y frecuentemente costoso. El objetivo de la presente guía de práctica clínica (GPC) es proveer recomendaciones clínicas basadas en evidencia para el diagnóstico y tratamiento de hemofilia en el seguro social del Perú (EsSalud). Métodos. Se conformó un grupo elaborador local (GEG-Local) conformado por especialistas en hematología y metodólogos. El GEG-Local formuló ocho preguntas clínicas a ser respondidas por la presente GPC. Se buscaron y seleccionaron GPC de hemofilia que respondieran a las preguntas planteadas y obtuvieran un puntaje mayor a 60% en los dominios uno y tres del instrumento Appraisal of Guidelines for Research and Evaluation II (AGREE-II). Durante el 2016 se realizaron búsquedas bibliográficas en Pubmed, EMBASE y biblioteca Cochrane, para actualizar siete preguntas clínicas de la GPC preseleccionada, y para responder una pregunta de novo. En reuniones de trabajo periódicas, el GEGLocal revisó la evidencia y formuló las recomendaciones y flujogramas usando la metodología Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Finalmente, la GPC fue aprobada con Resolución N° 32-IETSI-ESSALUD-2016. Resultados. La presente GPC abordó ocho preguntas clínicas. En base a dichas preguntas se formularon 22 recomendaciones (tres recomendaciones fuertes y 19 recomendaciones condicionales) y cuatro flujogramas. Conclusión. Este artículo es el resumen de la GPC de EsSalud, en la cual se valoró la evidencia científica disponible sobre diagnóstico y tratamiento de hemofilia.
Lista de verificación que debe acompañar a todo trabajo remitido a la Revista Anales de la Facultad de Medicina
Authors: Cabezas Sánchez César
Published: June 2018

Lista de verificación que debe acompañar a todo trabajo remitido a la Revista Anales de la Facultad de Medicina.
Intimate Partner Violence, Depression, and Child Growth and Development
Authors: Neamah Hind H. , Sudfeld Christopher , McCoy Dana Charles , Fink Günther , Fawzi Wafaie W. , Masanja Honorati , Danaei Goodarz , Muhihi Alfa , Kaaya Sylvia , Smith Fawzi Mary C.
Published: June 2018

BACKGROUND:

Evidence on the relationship between maternal depression and exposure to intimate partner violence (IPV) with child physical growth and development is equivocal. Our aim in the current study is to examine these relationships among women and their children in Tanzania.

METHODS:

The Bayley Scales of Infant Development and anthropometric measures were used to assess children 18 to 36 months of age (n = 1031). Maternal exposure to IPV and depression were assessed using the Tanzania Demographic and Health Survey questionnaire and the Patient Health Questionnaire-9, respectively. We used linear regression models to calculate standardized mean differences (SMDs) for developmental outcomes and generalized linear models to estimate the associations with nutritional status.

RESULTS:

Mild depressive symptoms in mothers (Patient Health Questionnaire-9 ≥5) and exposure to physical and sexual IPV were associated with lower SMDs for motor skills (−0.14 [P = .023] and −0.23 [P < .01], respectively), expressive communication (−0.13 [P = .187] and −0.23 [P < .01], respectively), receptive communication (−0.19 [P < .009] and −0.16 [P = .03], respectively), and cognitive development (−0.08 [P = .245] and −0.12 [P = .07], respectively). Exposure to physical and sexual IPV was associated with higher risk for stunting (relative risk = 1.6; P < .001).

CONCLUSIONS:

This study reveals that maternal depressive symptoms and IPV are associated with adverse child nutritional and developmental outcomes. Further research is needed to develop programs to address IPV and depression among women and enhance the growth and development of their children.
Outcomes in Mild to Moderate Isolated Thrombocytopenia
Authors: Schlappi Charles , Kulkarni Varsha , Palabindela Prasannalaxmi , Bemrich-Stolz Christina , Howard Thomas , Hilliard Lee , Lebensburger Jeffrey
Published: June 2018

OBJECTIVES:

Incidental isolated mild to moderate thrombocytopenia is a frequent laboratory finding prompting a referral to pediatric hematology-oncology. We tested the hypothesis that patients with isolated asymptomatic mild thrombocytopenia would not progress to require an intervention from a pediatric hematologist–oncologist.

METHODS:

This is a 5-year retrospective review of 113 patients referred to pediatric hematology–oncology for isolated thrombocytopenia. Initial, lowest, and current platelet counts along with clinical course and need for interventions were recorded. Thrombocytopenia was categorized as mild (platelet count: 101–140 × 103/μL), moderate (platelet count: 51–100 × 103/μL), severe (platelet count: 21–50 × 103/μL), and very severe (platelet count: ≤20 × 103/μL).

RESULTS:

Eight of 48 patients (17%) referred for initial mild isolated thrombocytopenia progressed to moderate thrombocytopenia at 1 visit. At present, 2 of these patients have moderate thrombocytopenia, 17 remain with mild thrombocytopenia, and 29 patients have resolved thrombocytopenia. Nine of 65 patients (14%) referred for moderate thrombocytopenia progressed to severe or very severe thrombocytopenia on 1 occasion. At present, no patients have severe thrombocytopenia, 18 remain with moderate thrombocytopenia, 14 improved to mild thrombocytopenia, and 33 have resolved thrombocytopenia. Only 3 patients required interventions from a hematologist, whereas 10 patients required therapy from other subspecialties.

CONCLUSIONS:

We only identified 3 patients (3%) with mild to moderate thrombocytopenia who required an intervention from a hematologist to improve platelet counts. Patients with isolated mild thrombocytopenia with a normal bleeding history and physical examination findings frequently have normalized their platelet counts within 1 month.
Treatment Selection in Pulmonary Arterial Hypertension: Phosphodiesterase Type 5 Inhibitors versus Soluble Guanylate Cyclase Stimulator
Authors: Watanabe Hiroshi ,   Department of Clinical Pharmacology and Therapeutics, Hamamatsu University School of Medicine, Hamamatsu, Japan and Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan
Published: June 2018

Pulmonary arterial hypertension is a chronic and life-threatening disease that if left untreated is fatal. Current therapies include stimulating the nitric oxide–soluble guanylate cyclase (sGC)–cyclic guanosine monophosphate axis, improving the prostacyclin pathway and inhibiting the endothelin pathway. Phosphodiesterase type 5 inhibitors, such as sildenafil, and the sGC stimulator riociguat are currently used in the treatment of pulmonary arterial hypertension. This article discusses the similarities and differences between phosphodiesterase type 5 inhibitors and sGC stimulator based on pharmacological action and clinical trials, and considers which is better for the treatment of pulmonary arterial hypertension.
Screening for toxoplasmosis during pregnancy: One-year experience in an Italian reference laboratory
Authors: Meroni Valeria , Genco Francesca
Published: June 2018

AIMS: To describe the experience of the Toxoplasmosis Laboratory of Infectious Disease Department University of Pavia, IRCCS Foundation, San Matteo Polyclinic Pavia, a reference laboratory for diagnosis of toxoplasmosis, in the investigation of pregnant women with suspected acute toxoplasmosis. METHODS: All sera were tested with LIAISON® Toxo IgM and IgG II, Toxo IgG Avidity II kits (DiaSorin, Saluggia, Italy), VIDAS Toxo IgG II and Toxo IgG Avidity (bioMérieux, Marcy l’Etoile, France ), IgM ISAGA (bioMérieux, Marcy l’Etoile, France) and ETI-TOXOK-A reverse PLUS (DiaSorin, Saluggia, Italy). When required (IgG negative/IgM positive women), IgG/IgM Western Blot II (LDBio, Lyon, France) was also performed. Prenatal diagnosis on amniotic fluid was done by nested PCR. All newborns were followed up to one year of age in order to exclude or confirm the diagnosis of congenital toxoplasmosis. All pregnant women with acute or undetermined stages of infection were treated. RESULTS: In the course of 2007, 236 women with suspected acute (IgM-positive) Toxoplasma infection were followed up. In the reference laboratory, 91 women had test results indicating acute toxoplasmosis, and 10 had undetermined status of infection. These 101 patients represented 42.8% of the 236 women referred. Acute toxoplasmosis could be excluded in the remaining 135 patients, of whom 53 were non-immune. Three infected newborns were observed, all from mothers tested for the first time during the third trimester of pregnancy. CONCLUSIONS: The role of a reference laboratory in suspected toxoplasmosis acquired during pregnancy is crucial to date the infection and discriminate between seroconversion and false positive anti-Toxoplasma IgM antibodies. This avoids unnecessary anxiety in immune women, provides correct counseling about primary prevention and periodic testing for seronegative ones, and allows early treatment and follow-up of pregnant women with acute infection and their newborns.
Surface characterization of polytetrafluoroethylene treated by atmospheric plasma
Authors: Al-Maliki H. , Károly Z. , Klébert Sz. , Kalácska G.
Published: June 2018

Polytetrafluoroethylene surface was treated by atmospheric DBD plasma for 1 min in ambient conditions. The effect of DBD plasma introduces signifi cant increasing of the surface energy (wettability) within 24 hours after treatment. However, the surface starts recovering to the original state with ageing. The surface elemental composition shows enhancing in oxygen content which suggests presenting the polar functional groups. The surface roughness exhibits a mild reduction within 24 hours after treatment. Whereas, the roughness values start to increase with the function of time.
Application of Taguchi technique to optimize the gma welding parameters and study of fracture mode characterization of AISI 304H welded joints
Authors: Rizvi S. A.
Published: June 2018

This research article is focusing on the optimization of different welding process parameters which affect the weldability of stainless steel (AISI) 304H, Taguchi technique was used to optimize the welding parameters and the fracture mode characterization was studied. A number of experiments have been conducted. L9 orthogonal array (OA) (3×3) was applied. Analysis of variance ( ANOVA) and signal to noise ratio (SNR) was applied to determine the effect of different welding parameters such as welding current, wire feed speed and gas flow rate on mechanical, microstructure properties of SS304H. Ultimate tensile strength (UTS), toughness, microhardness (VHN), and mode of fracture was examined to determine weldability of AISI 304H and it was observed from results that welding voltage has major impact whereas gas flow rate has minor impact on ultimate tensile strength of the welded joints. Optimum process parameters were found to be 23 V, 350 IPM travel speed of wire and 15 l/min gas flow rate for tensile strength and mode of fracture was ductile fracture for tensile test specimen.
A katalázkutatás kétszáz éve, 1818–2018
Authors: Góth László
Published: June 2018

Abstract:

L. J. Thénard and J. L. Gay-Lussac discovered hydrogen peroxide in 1818. Later, Thénard noticed that animal and plant tissues decompose hydrogen peroxide. The substance which is responsible for this reaction was named as catalase by O. Loew in 1900. The catalase enzyme was regarded as a diagnostic and a tumour marker in the late years of the 19th century and in the early years of the 20th century. Acatalasemia, an inherited deficiency of enzyme catalase, was studied in Japan, Switzerland and Hungary. The recent findings on catalase are focusing on the effects of reactive oxygen species and on the association of acatalasemia and diabetes mellitus. Orv Hetil. 2018; 159(24): 959–964.
Sarah Baker, Andy Bennett and Jodie Taylor, eds. 2013. Redefining Mainstream Popular Music
Authors: O'Dair Marcus
Published: June 2018

Sarah Baker, Andy Bennett and Jodie Taylor, eds. 2013. Redefining Mainstream Popular Music. New York and London: Routledge. 222pp. ISBN 978-0-415-80782-1 (pbk)
Editors' Introduction
Authors: Krüger Bridge Simone , Tochka Nicholas , Nowak Raphaël
Published: June 2018

Editors' Introduction
Introduction
Authors: Haupt Adam , Williams Quentin E , Alim H Samy
Published: June 2018

This double special issue explores hip hop activism and representational politics in selected countries from the global north and south. The authors in part one of this double issue offer key examples of the different forms that hip hop activism may take and offer meaningful insights into debates about agency in a media and cultural terrain that is shaped by US cultural imperialism and colonial legacies. Artists may exercise agency via performances that push linguistic, literary, aesthetic and political boundaries that aim to set off critical lyrical engagement with key issues or by confronting such issues sonically as a turntablist. They may also exercise agency in the context of workshops in dialogues between educators, learners, artists, activists and scholars. Effectively, this issue allows us to think about the ways in which hip hop has become a vehicle for marginalized subjects to address their respective political contexts.
Multilingual Activism in South African Hip Hop
Authors: Williams Quentin E
Published: June 2018

It is difficult to point exactly to the day multilingual activism emerged in South African hip hop culture, though we can arguably state such activism emerged out of a confluence of historical events that involved the oppression of black and coloured people by an aggressively oppressive apartheid regime. This article discusses the tactics and strategies of multilingual activism undertaken by pioneering hip hop groups Prophets of da City at the inception of hip hop in South Africa. It considers the historical transition from apartheid South Africa to the new South Africa and how new and emerging forms of multilingual activism such as the AfriKaaps movement are contributing to redefining what we mean by multilingualism. The article also links these forms of multilingual activism to an alternative politics of multilingual voice being promoted in the public space of the country.
NUMERICAL SIMULATION OF AIRFLOW AROUND VEHICLE MODELS
Authors: Thang Nguyen Van , Vinh Ha Tien , Tri Bui Dinh , Trong Nguyen Duy
Published: June 2018

This article carries out the numerical simulation of airflow over three dimensional car models using ANSYS Fluent software. The calculations have been performed by using realizable k-e turbulence model. The external airflow field of the simplified BMV M6 model with or without a wing is simulated. Several aerodynamic characteristics such as pressure distribution, velocity contours, velocity vectors, streamlines, turbulence kinetic energy and turbulence dissipation energy are analyzed in this study. The aerodynamic forces acting on the car model is calculated and compared with other authors.
Support for Lesbian and Gay Rights: How and Why the South Differs from the Rest of the Country
Authors: Lewis Gregory B. , Galope Reynold V.
Published: June 2018

The South provides far fewer legal protections for lesbian, gay, bisexual, and transgender Americans than does the rest of the country. Because state gay rights policies strongly reflect public opinion, trends in and the causes of Southerners' stronger opposition to homosexuality and gay rights are key to the future of lesbian and gay rights in the region. Using data for over 200,000 respondents to over 150 surveys, we assess the width, stability, and roots of Southern differences in beliefs about whether homosexual sex should be legal, schools should employ lesbian and gay teachers, same-sex marriage should be legal, and homosexual relations are "not wrong at all." We find strong and stable regional divergences that owe much to Southerners' greater religiosity, conervatism, and Republican party identification and their higher probabilities of being evangelical Protestants and African Americans. Migration patterns seem to maintain rather than to narrow or widen regional differences on gay rights.
Southern Fried Family Planning: Reproductive Politics in the South
Authors: Rinehart Christine Sixta , Woliver Laura R.
Published: June 2018

We examine regulations in thirteen Southern states regarding access to legal abortion, procedures for juveniles and minors seeking birth control or abortions, clinic regulations, and the dynamics of public funding of birth control and abortion. Southern state legislatures play an important strategic role in national anti-legal abortion politics. We analyze the paradox of the Southern population utilizing legal abortion and birth control at comparable levels to other regions of the country, while Southern legislatures consistently restrict access to these options. Our paper integrates gender, social class, race, and sexuality into our analysis of this aspect of Southern and national politics.
Rescue therapy with stent retrievers for thromboembolism during endovascular treatment of intracranial aneurysms
Authors: Demartini Junior Zeferino , Gatto Luana A. Maranha , Koppe Gelson Luis , Oliveira Tatiana F. von Hertwig de , Francisco Alexandre Novicki
Published: June 2018

ABSTRACT Thromboembolism is the most frequent complication in endovascular treatment of intracranial aneurysms, causing disability and death. As stent retrievers have achieved high rates of arterial recanalization in the management of ischemic stroke, these devices were tested as rescue therapy of thromboembolism during aneurysm embolization. We retrospectively analyzed 10 consecutive patients with transprocedural arterial occlusion, treated with mechanical thrombectomy at a single center. Good angiographic recanalization was achieved in eight cases, mTICI 3, 2b and 2a in five, three and two patients, respectively, without additional complications or any deaths. Five patients showed complete recovery (mRS 0) and all patients showed improvement of disability (average mRS 1.1) over a mean follow-up period of 31 months. Eight patients had good clinical recovery, while two remained with deficits (mRS 3 and 4). The study found that the stent retriever is a valuable, rapid and effective tool for restoring blood flow, improving the safety of endovascular treatment.
Gait in normal pressure hydrocephalus: characteristics and effects of the CSF tap test
Authors: Souza Ricardo Krause Martinez de , Rocha Samanta Fabrício Blattes da , Martins Rodrigo Tomazini , Kowacs Pedro André , Ramina Ricardo
Published: June 2018

ABSTRACT Normal pressure hydrocephalus (NPH), described by Hakim and Adams in 1965, is characterized by gait apraxia, urinary incontinence, and dementia. It is associated with normal cerebrospinal fluid (CSF) pressure and ventricular dilation that cannot be attributed to cerebral atrophy. Objectives: To evaluate gait characteristics in patients with idiopathic NPH and investigate the effect of the CSF tap test (CSF-TT) on gait. Methods: Twenty-five patients diagnosed with probable idiopathic NPH were submitted to the CSF-TT. The procedure aimed to achieve changes in gait parameters. Results: Fifteen gait parameters were assessed before and after the CSF-TT. Five showed a statistically significant improvement (p < 0.05): walking speed (p < 0.001), cadence (p < 0.001), step length (p < 0.001), en bloc turning (p = 0.001), and step height (p = 0.004). Conclusion: This study demonstrated that gait speed was the most responsive parameter to the CSF-TT, followed by cadence, step length, en bloc turning, and step height.