bluuebunny/crossref_metadata_2025 huggingface dataset:
EFEKTIVITAS COOLER 703E02 PADA SECTION 703 SEBAGAI PENDINGIN METHYL ESTER DI PT. ECOGREEN OLEOCHEMICALS BATAM PLANT
Authors: Nugraha Aditia Fian , Chalim Abdul , Lie Anderson
Published: December 2022

Shell and Tube Heat Exchanger 703E02 digunakan sebagai pendingin untuk campuran Methyl Ester-Gliserin agar  mempermudah proses pemisahan pada separator. Alat pendingin beroperasi secara kontinyu, sehingga perlu  dilakukan perhitungan efektivitas untuk mengetahui seberapa baik alat melakukan pertukaran panas, dan sebagai  evaluasi perlu atau tidaknya dilakukan maintenance pada alat. Metode perhitungan yang dilakukan berdasarkan  data yang didapatkan pada plant, dengan melakukan pengukuran suhu fluida secara manual menggunakan  Thermogun pada suhu masuk dan keluaran fluida dingin, sedang untuk fluida panas digunakan data dari indikator  temperatur yang sudah terpasang pada jalur. Flowrate pada pendingin tidak diketahui dan dilakukan perhitungan  menggunakan persamaan perpindahan panas. Untuk spesifikasi bahan yang digunakan didapat melalui  perpustakaan Process Engineering. Dari hasil perhitungan yang didapatkan efektivitas alat yang didapatkan  sebesar 0,4450 dengan NTU 0,7288. NTU menjadi tolok ukur besarnya perpindahan panas yang dilepas oleh alat  sehingga dengan hasil tersebut energi yang dilepas kecil dan efektivitas alat rendah. Perlu dilakukan pengecekan  secara berkala dan maintenance agar berjalan dengan baik.
PENGARUH KONSENTRASI PUTIH TELUR DALAM PEMBUATAN BUBUK KALDU JAMUR TIRAM DENGAN METODE FOAM MAT DRYING
Authors: Zamzami Muhammad , Dewi Ernia Novika
Published: December 2022

Monosodium Glutamate (MSG) sudah dikenal sejak lama sebagai bahan tambahan untuk menyedapkan dan  menguatkan rasa pada makanan. Terlalu banyak mengonsumsi MSG dapat menyebabkan gangguan pada kesehatan. Cara lain untuk menghasilkan rasa umami atau gurih pada makanan tanpa menggunakan MSG adalah  dengan olahan jamur berupa bubuk kaldu jamur. Salah satu cara untuk membuat bubuk kaldu jamur adalah menggunakan metode foam mat drying dimana proses pengeringan melibatkan pencampuran kaldu jamur dengan bahan pembusa untuk menghasilkan busa yang stabil. Pada penelitian ini, dilakukan pembuatan bubuk  kaldu jamur dengan variabel konsentrasi putih telursebagai bahan pembusa sebesar 10%, 15%, 20% , 25%, 30%,  35% (b/v). Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penambahan konsentrasi putih telur  dalam pembuatan bubuk kaldu jamur terhadap nilai yield dan pengujian organoleptik. Berdasarkan penelitian  yang telah dilakukan, nilai yield berbanding lurus dengan konsentrasi putih telur, dengan hasil terbaik pada  konsentrasi 35% yaitu sebesar 33,2%. Hasil terbaik berdasarkan uji organoleptik yang didapatkan pada variabel  konsentrasi putih telur 20%.
PEMANFAATAN KULIT KACANG TANAH DAN BAMBU SEBAGAI BAHAN BAKU PEMBUATAN BIOBRIKET DENGAN METODE KARBONISASI
Authors: Kusyanto Kusyanto , Rahim Marinda , Subakir Muhammad Yahya , Rahayu Ibnu Eka , Fitriyana Fitriyana
Published: December 2022

Kalimantan Timur menghasilkan kacang tanah sebanyak 654 ton pada tahun 2020, sementara itu produksi  bambu di Indonesia pada tahun 2019 sekitar 17,1 miliar batang. Perlu pengolahan bahan agar dapat digunakan  menjadi biobriket. Biobriket merupakan sumber energi terbarukan dan ekonomis. Penelitian ini bertujuan  untuk mengetahui pengaruh perbandingan pencampuran biomassa kulit kacang tanah dan bambu terhadap  kualitas biobriket berdasarkan standar SNI 01-6235-2000. Karbonisasi dilakukan pada kulit kacang tanah 450°C  dan bambu 500°C selama 60 menit. Arang dihaluskan kemudian diayak lebih kecil dari 70 mesh. Arang kulit  kacang tanah (KK) dan bambu (B) ditimbang 20 gram dengan komposisi 100%KK, 80%KK : 20%B, 60%KK : 40%B,  50%KK : 50%B , 40%KK : 60%B, 20%KK : 80%B, 100%B. Arang dicampurkan dengan perekat kanji 5 % dari massa  arang (1 gr kanji : air 25 ml). Dikeringkan pada suhu 80°C selama 24 jam. Hasil kombinasi terbaik didapatkan  pada kulit kacang tanah 20% dan bambu 80% dengan nilai kalor 6908,6 kal/g, kadar air 3,95%, kadar abu 6,27%,  kadar karbon terikat 73,2% telah memenuhi standar SNI 01-6235-2000, kecuali untuk kadar zat terbang 16,58%  masih belum memenuhi standar SNI 01-6235-2000.
PENGARUH WAKTU DAN KADAR ETANOL PADA MASERASI LIDAH BUAYA TERHADAP ANTISEPTIK HAND SANITIZER GEL
Authors: Dianda Tirza Putri , Suharti Profiyanti Hermien
Published: December 2022

Hand sanitizer merupakan pembersih tangan berbasis alkohol yang berfungsi untuk menghilangkan bakteri pada  tangan. Bahan utama dari hand sanitizer adalah alkohol. Alkohol yang digunakan pada percobaan ini adalah  etanol. Tujuan dari penelitian ini adalah mengetahui pengaruh kadar etanol dan lama maserasi lidah buaya  terhadap kemampuan antiseptik pada hand sanitizer gel. Lidah buaya ditambahkan pada hand sanitizer karena  kandungan saponinnya dapat membantu untuk membunuh bakteri. Lidah buaya dimaserasi menggunakan  etanol untuk memperoleh ekstraknya. Lama maserasi yang digunakan adalah tanpa maserasi, 3 hari maserasi,  dan 5 hari maserasi. Konsentrasi etanol yang digunakan untuk maserasi adalah 50%, 60%, dan 70%. Lama  maserasi dan kadar etanol yang digunakan untuk maserasi akan mempengaruhi kemampuan dalam menarik  komponen yang ada dalam lidah buaya, yang mana komponen tersebut berfungsi untuk menghambat bakteri.  Etanol yang digunakan untuk maserasi yang mana masih tertinggal dalam ekstrak juga berfungsi untuk  menghambat bakteri. Uji antibakteri dilakukan untuk melihat kemampuan hand sanitizer dalam membunuh  bakteri. Uji antibakteri yang digunakan adalah metode sumuran. Metode sumuran dipilih karena lebih mudah  dalam mengukur luas zona hambat yang terbentuk serta dapat menghasilkan zona hambat yang baik dan luas.  Kemampuan antiseptik hand sanitizer gel ditunjukkan dengan luas zona hambat yang terbentuk. Semakin besar  ukuran zona hambat yang dihasilkan, maka semakin besar daya hambat antiseptik terhadap bakteri. Penelitian  menujukkan bahwa hand sanitizer dengan lama maserasi lidah buaya 5 hari menggunakan etanol 70% memiliki  zona hambat terbesar, yaitu: 55mm. Hand sanitizer dengan lama maserasi 3 hari menggunakan etanol 50% dan  60% memiliki zona hambat terkecil yaitu sebesar 3 mm.
PEMANFAATAN PSIDIUM GUAJAVA DAN ANNONA MURICATA SEBAGAI GREEN CORROSION INHIBITOR TERHADAP PENURUNAN LAJU KOROSI PADA PIPA BAJA KARBON
Authors: Sa’diyah Jamilatus , Suharti Profiyanti Hermien
Published: December 2022

Korosi menjadi salah satu permasalahan pada industri, terutama pada perpipaan yang mengalami  kerusakan karena korosi. Dengan penambahan green corrosion inhibitor yang akan mengurangi laju korosi pada  baja. Green corrosion inhibitor digunakan sebagai alternatif dengan memanfaatkan senyawa tanin. Selain murah  dan aman dalam penggunaannya, ketersediaan bahannya juga mudah ditemukan dalam kehidupan sehari-hari.  Tujuan penelitian ini adalah mengetahui efisiensi daya hambat laju korosi pada pipa baja karbon dengan  menggunakan ekstrak daun jambu biji dan daun sirsak. Ekstrak daun jambu biji dan daun sirsak diperoleh dengan  cara maserasi kemudian hasil ekstrak didistilasi. Metode pengukuran laju korosi menggunakan weight loss. Spesimen baja karbon yang sudah dipotong kemudian direndam pada air laut dengan dan tanpa ekstrak daun  jambu biji dan daun sirsak, dengan perbandingan konsentrasi 0%; 25%; 50%; 75%; dan 100% dengan masa  perendaman selama 720 jam. Hasil penelitian didapatkan bahwa konsentrasi variabel dari daun jambu biji dan  daun sirsak yang optimal pada penambahan konsentrasi inhbitor korosi sebesar 100%. Hasil penelitian adalah  bahwa laju korosi terendah dari ekstrak daun jambu yang diperoleh yaitu 0,049 mm/tahun sedangkan untuk  ekstrak daun sirsak laju korosi terendah yang dihasilkan yaitu 0,091 mm/tahun dengan konsentrasi penambahan  100%. Nilai efisiensi inbitor terbaik pada daun sirsak yaitu 79,63 % sedangkan efisiensi daun jambu biji terbaik yaitu 86,21 % pada konsentrasi penambahan ekstrak 100%.
İnsan ve Muhiti: Muhit Kavramı Perspektifinden Din Eğitimi
Authors: ÇETİNEL Hasan
Published: December 2022

Doğumla ölüm arasında uzanan hayat çizgisi boyunca, insanın varlığı için hayati öneme sahip temel ihtiyaçların başında, sevgi ve güven temelli bir sosyal çevre yer almaktadır. Dâhil olduğu sosyal çevrenin etkisi altında insanın sosyal, kültürel bir yeniden doğuşuna daha tanıklık edilmektedir. Bu araştırmada Kur’ân-ı Kerim’de geçen, sıklıkla Türkçedeki çevre kelimesinin eş anlamlısı olarak kullanılmakta olan “muhit” kelimesi üzerinden insanın gelişiminde çevre etkisi olgusuna odaklanılmıştır. Bu amaçla ilk olarak eğitim ve gelişim psikolojisinin temel kavramlarından olan gelişim ve gelişim ilkelerine literatür taraması yoluyla değinilmiştir. İkinci aşamada ise “muhit” kelimesiyle aynı etimolojik kökene sahip olan bir grup kelimenin oluşturduğu semantik alan esas alınarak analizlerde bulunulmuştur. Bu kelimelerin oluşturduğu anlam alanı içerisinde muhitin; “çevreleme”, “kuşatma”, “duvar olma”, “koruma”, “tedbirli davranma”, “kuşatıcı, kapsamlı bilgi sahibi olma” anlamlarıyla oldukça zengin bir anlam alanı oluşturduğu tespit edilmiştir. Özellikle Kur’ân-ı Kerim’de Allah’a ait bir isim olarak takdim edilen Muhit’in, O’nun tüm varlık ve insan hakkındaki kuşatıcı, sınırsız bilgisini ifade etmekle beraber insanın ontolojik anlamda Allah düşüncesiyle kuşatılmışlığına dikkat çekilmiştir. Birbirini karşılayan iki kelime gibi duran “çevre” ve “muhit” kelime ikilisinden muhit üzerinden yapılan analizlerde, insan ve çevre etkileşimi bağlamında, genetik bir mirasın devamı niteliğinde belirli bir potansiyelle dünyaya gelmiş insanın, içine doğduğu muhit tarafından sosyo-kültürel anlamda yeniden inşa olunduğuna vurgu yapılmaya çalışılmıştır. Yapılan analizlerden hareketle bireyin sağlıklı gelişimi için çevreleme, koruma, kuşatma, tedbirli davranma, duvar olma anlamlarını tam anlamıyla karşılayan arzu edilir muhitlere olan ihtiyaca vurgu yapılmıştır. Konuya çocuğun inanç gelişimi ve din eğitimi noktasından bakıldığındaysa, “Muhit” sıfatıyla insanın tüm eylemlerinden haberdar, bilgisiyle düşünce ufkunu kaplayan bir ilah düşüncesinin küçük yaşlardan itibaren çocuğun zihinsel çevresinin ayrılmaz bir düşüncesi kılınması önem arz etmektedir.
The Effect of Competence, Motivation, Work Environment and Work Facilities on The Expenditure Treasurer Performance
Authors: Budiman Mohamad Fajar , Akadun Akadun , Milwan Milwan
Published: December 2022

Purpose – This study aims to determine and analyze the effect of competence, motivation, as well as work environment and facilities on the performance of the expenditure treasurer at the APBN management unit in North Kalimantan Province.
Methodology – The participants were 213 expenditure treasurers which were selected by the simple random sampling technique. Furthermore, the number of samples was determined by using the Yamane formula and a total of 139 respondents were obtained. The data collection technique used questionnaires, namely the Guttman, Likert, and Rating Scales. In addition, the data were analyzed using multiple linear regression with the aid of SPSS For Windows.
Findings – The results showed competence, motivation, as well as work environment and facilities had a positive and significant effect on the performance of the expenditure treasurer. Therefore, each of the work units managing the State Budget in North Kalimantan Province needs to pay more attention to the factors that affect performance.
Originality – This study provides a new perspective on the effect of competence, motivation, as well as work environment and facilities on expenditure treasurer performance, which has never been carried out in previous literature.
МОСКОВСКАЯ ОБЩИНА СЕСТЕР МИЛОСЕРДИЯ «УТОЛИ МОЯ ПЕЧАЛИ»
В ГОДЫ РУКОВОДСТВА КНЯГИНИ Н. Б. ШАХОВСКОЙ
Authors: Блохина Наталья Николаевна
Published: December 2022

Деятельность московской общины сестер милосердия «Утоли моя печали», как и многих других московских общин подобного рода, была уникальна, поскольку сочетала в себе не-сколько функций. Главными были дело милосердия и подготовка сестер, ухаживающих за нуждающимися в этом людьми. Вместе с тем здесь оказывался самый широкий спектр со-циальной и медицинской помощи: от ухода за «умалишенными», заботы о сиротах и пре-старелых до оказания помощи раненым воинам. Община была создана усилиями княгини Н. Б. Шаховской, одной из многих русских женщин-подвижниц этого времени, отдавших всю свою жизнь на служение страждущим, как к этому призывает Евангелие и христиан-ская жизнь. В статье раскрываются сложные взаимоотношения общины с Российским Красным Крестом, а также нелегкий труд всех насельниц общины, включая и ее начальни-цу Н. Б. Шаховскую, которой приходилось постоянно искать оптимальный путь оказания помощи в условиях тяжелой борьбы с бедностью, отсутствием средств на развитие общины и многими неблагоприятными обстоятельствами жизни.
The activity of the Moscow community of sisters of mercy «Assuage my sorrows», like many oth-er Moscow communities of this kind, was unique, as it combined several functions. The main thing was the work of mercy and the training of sisters who care for people in need. At the same time, the widest range of social and medical assistance was provided here: from caring for the «insane», caring for orphans and the elderly to helping wounded soldiers. The community was created by the efforts of Princess N. B. Shakhovskaya, one of the many Russian women ascetics of that time, who devoted their entire lives to serving the suffering, as the Gospel and Christian life call for. The article reveals the complex relationship of the community with the Russian Red Cross, as well as the hard work of all the inhabitants of the community, including its head and many adverse cir-cumstances of life.
ЖИЗНЕННЫЙ ПУТЬ ГЛАЗАМИ ЭТНОГРАФА
Authors: Дурасов Геннадий Петрович
Published: December 2022

Воспоминания этнографа, агиографа, духовного писателя, коллекционера и тонкого знатока русской традиционной культуры Г. П. Дурасова представляют собой краткий очерк жизненного пути автора, полного «неслучайных» встреч. Мы продолжаем публиковать отдельные очерки, отобранные автором для нашего журнала, касающихся этнографической тематики. Многолетнее сотрудничество и дружба коллектива журнала с Геннадием Петровичем не раз были ознаменованы его яркими публикациями на разные темы. Яркий язык автора, его острый взгляд и особая памятливость относительно культурного прошлого давно уже снискали ему читательское признание. Данный очерк содержит не публиковавшиеся ранее воспоминания о годах учебы, первых экспедициях и т. д. Христианство, православие всегда сопровождало автора на жизненном пути и определяло его жизненные интересы.
The memoirs of the ethnographer, hagiographer, spiritual writer, collector and connoisseur of Russian traditional culture G. P. Durasov are a brief outline of the author's life path, full of «non-random» meetings. We continue to publish individual essays, selected by the author for our journal, relating to ethnographic topics. Long-term cooperation and friendship of the journal's staff with Gennady Petrovich have been marked by his bright publications on various topics more than once. The author's bright language, his sharp gaze and special memory of the cultural past have long won him reader recognition. This essay contains previously unpublished memoirs about the years of study, the first expeditions, etc. Christianity, Orthodoxy has always accompanied the author on the path of life and determined his vital interests.
КОЛЛЕКЦИЯ ОТКРЫТОК НАЧАЛА XX в. КАК ДОКУМЕНТ ЭПОХИ: ОТКРЫТЫЕ ПИСЬМА РУССКИХ ПУТЕШЕСТВЕННИКОВ В РОССИЮ
Authors: Шляхтина Наталья Валерьевна
Published: December 2022

Публикация эпистолярного наследия, в данном случае открыток, представляется важной, поскольку дает читателю возможность познакомиться с конкретной семейной историей (а именно – с документами известной своими творческими и служилыми именами семьи Добровых), а также открывает панораму жизни русских путешественников за границей в начале XX в. Информация в письмах эскизна, нет развернутых описаний и рассуждений. Тем не менее они не только передают настроение, но и дают понимание особенностей европейской жизни того времени. Скажем, оценка Швейцарии как страны «разбогатевшего крестьянина» может быть понята только в контексте положения этой страны в европейском сообществе. В письмах Европа воспринимается без взгляда «снизу вверх» при всей доброй открытости и уважении к ее культуре.
The publication of epistolary heritage, in this case, postcards, is important, because it gives the reader the opportunity to get acquainted with a specific family history (namely, with documents known for their creative and service names of the Dobrov family), and also opens up a panorama of the life of Russian travelers abroad at the beginning of the 20th century. . The information in the letters is sketchy, there are no detailed descriptions and reasoning. Nevertheless, they not only convey the mood, but also give an understanding of the peculiarities of the European life of that time. For example, the assessment of Switzerland as a country of a "rich peasant" can only be understood in the context of the position of this country in the European community. In the letters, Europe is perceived without a “bottom-up” look, with all the good openness and respect for its culture.
Combined multiomics analysis reveals the mechanism of CENPF overexpression-mediated immune dysfunction in diffuse large B-cell lymphoma in vitro
Authors: Yang Dan , Wang Jia , Hu Mingqiu , Li Feng , Yang Feifei , Zhao Youcai , Xu Yanli , Zhang Xuezhong , Tang Lijun , Zhang Xiuqun
Published: December 2022

Diffuse large B-cell lymphoma (DLBCL) is one of the most common aggressive B-cell lymphomas with significant heterogeneity. More than half of patients are cured, but 40%–45% still face relapse or develop drug resistance, and the mechanism is not yet known. In this study, Centrimeric protein F (CENPF) overexpression was found in several DLBCL patients with relapsed or refractory disease compared to patients with complete remission. Thus, the human DLBCL cell line SU-DHL-4 was chosen for this study, and CENPF was upregulated in that cell line by using an adenovirus in vitro. Mass spectrometry-based quantitative proteome analysis was first performed, and the results showed that the expression levels of various proteins were increased when CENPF was upregulated, and these proteins are mainly involved in cellular processes, biological regulation, immune system processes and transcriptional regulator activity. Bioinformatics data analysis revealed that the main enriched proteins, including UBE2A, UBE2C, UBE2S, TRIP12, HERC2, PIRH2, and PIAS, were involved in various ubiquitin-related kinase activities and ubiquitination processes. Thus, ubiquitinome analysis was further performed, and the results demonstrated that proteins in many immune-related cellular pathways, such as natural killer cell-mediated cytotoxicity, the T-cell receptor signaling pathway and the B-cell receptor signaling pathway, were significantly deubiquitinated after CENPF was upregulated in DLBCL cells. Furthermore, TIMER2.0 was also used to reveal the association between CENPF and immune infiltration in DLBCL. The results showed that CENPF expression was positively correlated with CD8+ T cells, NK cells and B lymphocytes in DLBCL samples but negatively correlated with regulatory T cells. Aberrant activation of CENPF may induce immune dysregulation in DLBCL cells by mediating protein deubiquitination in various immune signaling pathways, which leads to tumor escape of DLBCL, but further experimental validation is still needed.
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway
Authors: Ning Shili , Chen Yuzhuo , Wang Guangzhi , Liu Yongtai , Yang Yingchi , Zhang Zhongtao
Published: December 2022

Background

Colorectal cancer is a common malignancy of the gastrointestinal tract, and its incidence and mortality rates have increased in recent years. RNF128 is an E3 ubiquitin ligase that plays an important role as a suppressor gene or oncogene in various cancers, but its mechanism in colorectal cancer is not yet clear. The aim of this study was to investigate the role and mechanism of RNF128 in colorectal cancer.

Methods

The expression of RNF128 in colorectal cancer tissues was assessed by immunohistochemistry and western blotting. The proliferation ability of colorectal cancer cells was measured by colony formation assay and CCK-8 assay, the migration and invasion ability of colorectal cancer cells was measured by wound healing assay and transwell assay, and the protein expression levels of the Hippo signaling pathway and its target gene were examined by western blotting. Immunoprecipitation was used to assess the interaction of RNF128 with MST. In vivo, a xenograft tumor model was used to detect the effect of RNF128 on tumor growth.

Results

At the tissue level, the expression level of RNF128 was significantly higher in colorectal cancer tissues than in adjacent normal tissues. In LoVo cells and HCT116 cells, the proliferation, migration and invasion abilities were significantly reduced with RNF128 knockdown. At the protein level, knockdown of RNF128 resulted in significant activation of the Hippo signaling pathway. In vivo experiments, the volume and weight of xenograft tumors in nude mice were significantly decreased compared with those in the normal control group with RNF128 knockdown.

Conclusion

RNF128 promotes the malignant behaviors of colorectal cancer cells by inhibiting the Hippo signaling pathway, which may provide a new target for colorectal cancer prevention and treatment.
Efficacy and safety of CD22-specific and CD19/CD22-bispecific CAR-T cell therapy in patients with hematologic malignancies: A systematic review and meta-analysis
Authors: Li Lili , Wang Luqin , Liu Qinhua , Wu Zhonghui , Zhang Yulong , Xia Ruixiang
Published: December 2022

Background

CD22 single and CD19/CD22 bispecific targeted chimeric antigen receptor T (CAR-T) cell therapy are promising immunotherapy modalities for the treatment of hematologic malignancies. The aim of this study was to assess the efficacy and safety of CD22 and CD19/CD22 targeted CAR-T cell therapy by summarizing the existing evidence.

Methods

Electronic databases including PubMed, Embase, and Scopus were comprehensively searched from inception up to November 30, 2022. Pooled response rates and minimal residual disease (MRD) negative response rates, cytokine release syndrome (CRS) rates and neurotoxicity rates were calculated. Subgroup analysis was performed based on the type of immunotherapy.

Results

Ten clinical studies including 194 patients with hematologic malignancies were included after a systematical screening of literature. The pooled complete response (CR) rates of CD22 and CD19/CD22 CAR-T cell therapy for relapsed or refractory B-cell lymphoblastic leukemia (B-ALL) were 0.75 (95% CI: 0.60 - 0.88) and 0.87 (95% CI: 0.76 - 0.96). The overall MRD negative response rates of CD22 and CD19/CD22 CAR-T were 0.54 (95% CI: 0.42 - 0.66) and 0.91 (95% CI: 0.47 - 0.88). Pooled CRS rates of CD22 targeted and CD19/CD22 targeted immunotherapy were 0.92 (95% CI: 0.82 - 0.98) and 0.94 (95% CI: 0.82 - 1.00), respectively.

Conclusion

Both CD22 and CD19/CD22 CAR-T immunotherapy demonstrated favorable efficacy and acceptable adverse events in the treatment of hematologic malignancies. Well-designed and large sample-sized clinical trials are warranted.
Impact of plateau pika burrowing activity on the grass/sedge ratio in alpine sedge meadows in China
Authors: Yao Xiang , Wang Haoran , Zhang Saiqi , Oosthuizen Maria , Huang Yilin , Wei Wanrong
Published: December 2022

Introduction

Burrowing activities of plateau pikas cause widespread bare patches in alpine meadows on the Qinghai-Tibet Plateau, affecting the plant community composition and forage production. However, it is not clear how these bare patches influence the main forage composition in alpine meadows.

Methods

Therefore, we investigated the plant communities in bare patches (BP) and neighboring control plots (CK) in alpine meadows in Maqu county in the Gannan region of China.

Results

Our results showed that plant communities in the CK plots differed from those in the BP plots. The sedge cover, number of sedge species and number of grass species were all significantly higher in the CK plots compared to the BP plots. However, grass cover and its dry weight were significantly higher in the BP plots. Grass cover and the grass dry weight in the BP plots were 1.859 times and 1.802 times higher than that in the CK plots across the five sites, respectively. Grasses also had a significantly higher cover and dry weight than sedge in the BP plots, grass cover was 66.5 times higher than the sedge cover, and the grass dry weight was 68.242 times that of the sedge dry weight. Therefore, bare patches resulting from plateau pika burrowing activity significantly increase the grass/sedge ratio in alpine meadows.

Discussion

A potential explanation is that grasses have a stronger reproductive potential than sedges in bare soil. This has implications for pasture yields since grasses have a higher biomass per unit area compared to sedges in alpine meadows.
Dealing with opposites as a mechanism of change in art therapy in personality disorders: A mixed methods study
Authors: Haeyen Suzanne , Ziskoven Johannes , Heijman Jackie , Joosten Evelien
Published: December 2022

Introduction

Personality disorders can be characterized by emotion regulation problems, difficulties in self-regulation and by dichotomous, black-and-white thinking. Dealing with opposites as a mechanism of change used by art therapists might be beneficial for people diagnosed with a personality disorder. This study examined the overall question if andin what waydealing with opposites in art therapy is a mechanism of change in achieving personal therapeutic goals.

Method

A convergent parallel mixed-methods pilot study was performed among patients with a personality disorder (N =32). Participants received four sessions of art therapy focused on opposites. They completed questionnaires on emotion regulation, positive and negative affect and sense of emotional balance before and after each session. Additionally, they completed a questionnaire on self-expression before and after the four sessions. Furthermore, 10 interviews (eight patients/two therapists) were conducted.

Results

Quantitative results comparing baseline versus after the four sessions showed a significant change indicating that there might be a positive change regarding self-expression and emotion regulation (t = −2.45,p = 0.02, ES d = 0.30). A significant change was measured in acceptance of emotional responses (Z = −2.66,p = 0.01) and the state of emotion was rated as more balanced (Z = −2.19,p = 0.03). No further significant changes were found. Qualitative results showed that using opposites in art therapy often helped to gain insight, self-exploration and self-awareness and could facilitate confrontation as well as acceptance although sometimes it was (too) confronting.

Discussion

Integration of conflicting emotions, behaviors, and thoughts were promoted by the explicit use of opposites and supporting coherent representation. Practice based recommendations are therefore to make more explicit use of dealing with opposites as a theme in art therapy. Also, we recommend more research on different mechanisms of change to refine the theory of change that provides an underpinning rationale and structure for art therapy. The results of this research should be regarded as exploratory given the small sample size and limited amount of therapy sessions.
Sfery zgody i konfliktu w polskim dyskursie politycznym wokół strategii walki z pandemią COVID-19
Authors: Łotocki Łukasz , Mikiński Krzysztof
Published: December 2022

The paper analyses the spheres of agreement and conflict in the political discourse around the strategy of combating the COVID-19 pandemic in Poland between February 2020 and May 2022. The paper identifies the dominant topoi present in the political discourse on the discussed topic. Particular attention was paid to the discourse around such issues as the definition of the initial situation, the introduction of restrictions and limitations, state policy on vaccination against COVID-19. The analysis shows that the main dividing lines in the political discourse related to COVID-19 have become less dependent on the general polarisation present on the Polish political scene. On many occasions, the main ruling party and the main opposition party did not differ in their views on the strategic assumptions adopted to fight the pandemic. Among the parties present in the parliament, the main dividing line was between politicians from the Confederation’s parliamentary group and those from the other groups.
Gospodarka polska w czasie pandemii COVID-19: spowolnienie czy regres?
Authors: Staniszewski Robert Miron
Published: December 2022

The article conducts a multidimensional diagnosis of the state of the Polish economy after two years of the COVID-19 pandemic. The author assessed the impact of the pandemic on the situation of enterprises and Polish households. The reference to the analysis are above mentioned such variables as: gross domestic product (GDP), CPI/HICP inflation, domestic demand, retail sales of goods, registered unemployment rate, consumer situation (BWUK, WWUK), economic situation, bankruptcy proceedings, restructuring proceedings, etc. The issues raised in the article have been grouped into four thematic blocks, i.e.: 1) the restrictiveness of the policy of the government of Mateusz Morawiecki at individual stages (waves) of the pandemic, 2) the impact of the COVID-19 pandemic on key economic indicators, 3) the impact of the pandemic on indicators regarding the perception of the economic and consumer situation, 4) the social perception of the impact of the pandemic on the standard of living of Poles, the perception of the government of Mateusz Morawiecki and the actions taken by it concerning economic restrictions. This part is based on the results of the public opinion poll Opinion of Poles on the activities of the government of Mateusz Morawiecki during the coronavirus pandemic, which was carried out under the direction of the author in May 2021. For the purposes of the article, the author formulated a research thesis, i.e. the COVID-19 pandemic affected the state of the Polish economy, slowed it down, but did not lead to a collapse such as regression.
Rynek pracy a przemiany społeczne i gospodarcze w świecie post-pandemicznym
Authors: Zawadzki Piotr W.
Published: December 2022

The pandemic is an accelerator of economic, technological and social changes. Despite pessimistic forecasts, Poland went unscathed by the pandemic crisis, which is the general conclusion of the article. This is evidenced both by economic data and market statistics. The first part of the article focuses on the economic background of the changes. The second one diagnoses the state of the Polish labor market, which is the main subject of the article. In the following sections author analyses the social consequences of the crisis, and on this basis, draws conclusions about the prospects of the Polish labor market after the pandemic.
The Content Scope of Airline Sustainability Reporting According to the GRI Standards—An Assessment for Europe’s Five Largest Airline Groups
Authors: Rüger Martin , Maertens Sven Ulrich
Published: December 2022

The aviation industry is facing pressure from stakeholders to transform towards greater sustainability. From a managerial and marketing perspective, not only the actual implementation and achievements of sustainability measures, but also their communication to stakeholders is likely to be crucial—and in many cases even legally required. This research evaluates the scope of sustainability and corporate social responsibility (CSR) reporting of Europe’s five largest airline groups for or from the year 2019, just prior the COVID-19 crisis. For this, dedicated sustainability reports and non-financial statements of Air France-KLM, easyJet, International Airlines Group, Lufthansa Group and Ryanair are evaluated and compared in a qualitative content analysis, using the Standards of the Global Reporting Initiative (GRI) as reference categories. The results indicate that the sustainability publications differ by airline business model, as the two low-cost carriers report less content in non-financial statements only, without publishing any standalone sustainability reports. Independent of the business model, most airlines surprisingly neglect the economic dimension of sustainability. The airline sector could improve its sustainability marketing by reporting both their economic, environmental, and social impacts and achievements.
Breeding of the Long-Grain Restorer of Indica-Japonica Hybrid Rice by Using the Genetic Effects of Grain Shape QTLs
Authors: Liu Keke , Peng Zequn , Sun Zhihao , Zhou Zhengping , Li Yanhui , Zhou Ran , He Dengmei , Huang Chenbo , Chen Daibo , Cheng Shihua , Cao Liyong , Zhan Xiaodeng , Sun Lianping
Published: December 2022

Grain shape improvement, which determines grain yield, quality traits and commercial value, is an extremely important aspect of rice breeding. Grain size is controlled by multiple genes, and Maker Assistant Selection (MAS) breeding is effective for breeders in developing stable and efficient markers to aggregate these genes in order to speed up the selection of new lines with desirable traits during the breeding process. In this study, functional markers were developed based on the sequence differences of five grain-shaped genes (GL7, GW6a, GS6, GW5 and TGW6) between the long-grain japonica rice variety Zhendao and the indica-japonica restorer R2027. We then constructed a population of recombinant inbred lines (RILs) based on their cross. The newly designed functional markers were used to genotype grain-size genes, and a genetic effect analysis was conducted to screen high-quality long-grain restorers. Our results reveal diverse effects of different genes on grain size, and the five genotypes were distributed in the 36 selected BC1F8 lines. Specifically, gw5 positively regulates grain width and 1000-grain weight, gl7 and gs6 positively regulate grain length but negatively regulate grain width and 1000-grain weight, tgw6 positively regulates grain length and gw6a positively regulates 1000-grain weight. The most outstanding outcome is that 5 of the 36 lines achieved in this study showing an excellent performance of long grain and yield characters are ideal materials not only for studying the interaction and genetic effects between polygenes but also as restorers or donors for dominant genes in indica-japonica hybrid rice breeding.
Potential Assessment of Selenium for Improving Nitrogen Metabolism, Yield and Nitrogen Use Efficiency in Wheat
Authors: Zhang Haiwei , Du Bin , Jiang Shuochen , Zhu Jianqiang , Wu Qixia
Published: December 2022

In wheat production, improving resource utilization and grain yield is the goal researcher have been pursuing. This study aimed to investigate if a regulated nitrogen (N) and selenium (Se) fertilizer management could increase wheat yield and N use efficiency (NUE). This study reports the effects of three N application levels (N0: 0 kg N ha−1, N1: 180 kg N ha−1, N2: 270 kg N ha−1) and a combination of three Se application levels (Se0: 0 g Se ha−1, Se1: 450 g Se ha−1, Se2: 900 g Se ha−1) on N metabolism, NUE and yield in wheat in 2020–2021. Compared with N0, wheat yield increased by 44.76% in N1 and by 54.32% in N2, and the activity of N-metabolizing enzymes increased by 25.15~35.03% in N1 and by 32.01~51.27% in N2. Compared with N1, the apparent recovery efficiency of N, the agronomic N use efficiency and the partial factor productivity of applied N decreased by 15.71%, 28.00% and 28.93% in N2, respectively. Compared with Se0, the 1000-grain weight increased by 3.93% in Se1 and by 4.87% in Se2, and the activity of nitrogen-metabolizing enzymes increased by 4.23~4.91% in Se1 and by 6.65~8.46% in Se2. We conclude that Se could improve the wheat 1000-grain weigh and N metabolism and has the potential to increase wheat yield and NUE.
Crop Productivity, Nutritional and Economic Benefits of No-Till Systems in Smallholder Farms of Ethiopia
Authors: Mupangwa Walter , Yahaya Rabe , Tadesse Ephrem , Ncube Bongani , Mutenje Munyaradzi , Chipindu Lovemore , Mhlanga Blessing , Kassa Abrham
Published: December 2022

Smallholder maize and wheat production systems are characterized by high drudgery. On-farm trials were run for three seasons in Ethiopia. The study assessed the effect of 2 WT direct seeding and growing season on (1) soil quality, and (2) maize and wheat productivity, energy and protein gains, and gross margins, on smallholder farms in Ethiopia. For the wheat crop, the effect of different soil types and agroecological conditions on productivity was assessed. The treatments in paired plots were (i) conventional ploughing practice and (ii) no-till (NT). Soil properties, crop yield, nutrition gains and gross margins were determined. No-till improved soil properties in the short term. No-till produced 1210–1559 kg ha−1 grain, 18–29 GJ ha−1 energy and 121–194 kg ha−1 proteins, and generated 358–385 US$ ha−1 more than the conventional practice in the maize system. In the wheat system, no-till treatment had 341–1107 kg ha−1 grain, 5–16 GJ ha−1 energy and 43–137 kg ha−1 proteins, and generated 230–453 US$ ha−1 more than conventional practice. No-till can be more productive and profitable in the Ethiopian maize and wheat-based cropping systems.
Relationship between the Dynamic Characteristics of Tomato Plant Height and Leaf Area Index with Yield, under Aerated Drip Irrigation and Nitrogen Application in Greenhouses
Authors: Xiao Zheyuan , Lei Hongjun , Jin Cuicui , Pan Hongwei , Lian Yingji
Published: December 2022

The current study was undertaken to investigate the dynamic characteristics of the tomato crop, such as its plant height and leaf area index (LAI), based on the effective cumulative temperature. This was assessed under aerated drip irrigation (ADI) conditions and the application of a specific nitrogen (N) dose, and their relationship with the yield of the crop was formulated. The study was conducted in a greenhouse located in Zhengzhou, Henan province, China. The assessment conditions were the two irrigation methods, ADI and conventional drip irrigation (CK), and the three N application rates, i.e., 0, 140, and 210 kg ha−1. The logistic and Richards models were used to fit dynamic equations for plant height and LAI under the different treatments to quantify the characteristic parameters and understand their relationship with yield. The results revealed that the growth of the tomato plant fitted well with the logistic and Richards model at R2 > 0.98 (p < 0.01), regardless of the treatments. ADI and N application were found to significantly increase the maximum growth rate and average growth rate over the rapid growth period based on the tomato plant height and LAI. They were also noted to reduce the effective cumulative temperature at which plant height entered the rapid growth period (p < 0.05), thereby increasing the time spent in the nutritional growth phase. This is an essential precursor for the better development of subsequent reproductive organs. Tomato yields also confirm it: the highest yield of 85.87 t ha−1 was obtained with 210 kg N ha−1 for the ADI treatment, with an increase of 13.8%, 12.2%, and 39.6% compared to the CK–210 kg N ha−1, ADI–140 kg N ha−1, and ADI–0 kg N ha−1 treatments, respectively (p < 0.05). Grey correlation analysis showed that the characteristic parameters closely related to yield were all from the ADI and N application treatments. Furthermore, it was observed that the effective cumulative temperature and the maximum growth rate of the LAI at which the LAI entered the slow growth phase were the key growth characteristic parameters affecting tomato yield. This study provides a scientific basis for regulating the growth dynamics and yield of vegetables in greenhouse facilities under ADI and N application.
Expansive Soil Stabilization with Lime, Cement, and Silica Fume
Authors: Al-Gharbawi Ahmed S. A. , Najemalden Ahmed M. , Fattah Mohammed Y.
Published: December 2022

The type of soil known as expansive soil is capable of changing its volume through swelling and contracting. These types of soils are mostly composed of montmorillonite, a mineral with the capacity to absorb water, which causes the soil to heave by increasing its volume. Due to their capacity to contract or expand in response to seasonal fluctuations in the water content, these expansive soils might prove to be a significant risk to engineering structures. Many studies have dealt with swelling soils and investigated the behavior of these soils, as well as their improvement. In this study, three percentages of lime, cement, and silica fume (5, 7, 9%) are used to stabilize the expansive soil, and the work is divided into two sections: the first is using a consolidation test to record the free swell and swell pressure for the untreated and treated soils; in the second part, the grouting technique is utilized as a process that can be applied in the field to maintain the improvement in the bearing capacity. It is concluded that the soil stabilized with different percentages of lime, cement, and silica fume exhibits a decrease in both free swell and swelling pressure by approximately 65% and 76%, respectively, as compared with untreated soil. The soil grouted with silica fume increases the bearing capacity of footings resting on the grouted soil by approximately 64% to 82% for the soil treated with 5% and 9% silica fume, respectively, as compared with untreated soil.
Propagation of Perturbations in the Lower and Upper Atmosphere over the Central Mediterranean, Driven by the 15 January 2022 Hunga Tonga-Hunga Ha’apai Volcano Explosion
Authors: Madonia Paolo , Bonaccorso Alessandro , Bonforte Alessandro , Buonocunto Ciro , Cannata Andrea , Carleo Luigi , Cesaroni Claudio , Currenti Gilda , De Gregorio Sofia , Di Lieto Bellina , Guerra Marco , Orazi Massimo , Pasotti Luigi , Peluso Rosario , Pezzopane Michael , Restivo Vito , Romano Pierdomenico , Sciotto Mariangela , Spogli Luca
Published: December 2022

The Hunga Tonga-Hunga Ha’apai volcano (Pacific Ocean) generated a cataclysmic explosion on 15 January 2022, triggering several atmospheric disturbances at a global scale, as a huge increase in the total electron content (TEC) in the ionosphere, and a pressure wave travelling in the troposphere. We collected and analysed data over the Mediterranean to study these disturbances, and in particular, (i) data from the barometric and infrasonic stations installed on Italian active volcanoes by the Istituto Nazionale di Geofisica e Vulcanologia (INGV) for investigating the tropospheric pressure waves; (ii) barometric data from the INGV-TROPOMAG and SIAS (Sicilian Agro-meteorological Information System) networks, for investigating the interaction between the orography and pressure waves; (iii) ionograms from the Advanced Ionospheric Sounder-INGV ionosonde at Gibilmanna (Sicily, Italy); (iv) data from the RING (Rete Italiana Integrata GNSS) network, to retrieve the ionospheric TEC; (v) soil CO2 flux data from the INGV surveillance network of Vulcano Island. The analysis of the ground-level barometric data highlights that pressure waves were reflected and diffracted by the topographic surface, creating a complex space–time dynamic of the atmospheric disturbances travelling over Sicily, driven by the interference among the different wavefronts. The ionograms show that a medium-scale travelling ionospheric disturbance (MSTID), with a horizontal wavelength of about 220 km and a period of about 35 min, propagated through the ionospheric plasma in the correspondence of the first barometric variations. Moreover, comparing detrended TEC and barometric data, we further confirmed the presence of the aforementioned MSTID together with its close relation to the tropospheric disturbance.
In-Depth Examination of Machine Learning Models for the Prediction of Ground Temperature at Various Depths
Authors: Yang Jong-Won , Dashdondov Khongorzul
Published: December 2022

Ground temperature (GT) or soil temperature (ST) is simply the measurement of the warmness of the soil. Even though GT plays a meaningful role in agricultural production, the direct method of measuring the GT is time-consuming, expensive, and requires human effort. The foremost objective of this study is to build machine learning (ML) models for hourly GT prediction at different depths (5, 10, 20, and 30 cm) with the optimum hyperparameter tuning with less complexity. The present study utilizes a statistical model (multiple linear regression (MLR)) and four different ML models (support vector regression (SVR), random forest regression (RFR), multi-layered perceptron (MLP), and XGBoost (XGB)) for predicting GT. Overall, 13 independent variables and 5 GTs with different depths as response variables were collected from a meteorological station at an interval of 1 h between 1 January 2017 and 1 July 2021. In addition, two different input datasets named M1 (selected number of parameters) and M2 (collected dataset with all variables) were used to assess the model. The current study employed the Spearman rank correlation coefficient approach to extract the best features and used it as the M1 dataset; in addition, the present study adopted regression imputation for solving the missing data issues. From the results, the XGB model outperformed the other standard ML-based models in any depth GT prediction (MAE = 1.063; RMSE = 1.679; R2 = 0.978 for GT; MAE = 0.887; RMSE = 1.263; R2 = 0.979 for GT_5; MAE = 0.741; RMSE = 1.025; R2 = 0.985 for GT_10; MAE = 0.416; RMSE = 0.551; R2 = 0.995 for GT_20; MAE = 0.280; RMSE = 0.367; R2 = 0.997 for GT_20). Therefore, the present study developed a simpler, less-complex, faster, and more versatile model to predict the GT at different depths for a short-term prediction with a minimum number of predictor attributes.
Independently Optimized Orbital Sets in GRASP—The Case of Hyperfine Structure in Li I
Authors: Li Yanting , Jönsson Per , Godefroid Michel , Gaigalas Gediminas , Bieroń Jacek , Marques José Pires , Indelicato Paul , Chen Chongyang
Published: December 2022

In multiconfiguration Dirac–Hartree–Fock (MCDHF) calculations, there is a strong coupling between the localization of the orbital set and the configuration state function (CSF) expansion used to determine it. Furthermore, it is well known that an orbital set resulting from calculations, including CSFs describing core–core correlation and other effects, which aims to lower the weighted energies of a number of targeted states as much as possible, may be inadequate for building CSFs that account for correlation effects that are energetically unimportant but decisive for computed properties, e.g., hyperfine structures or transition rates. This inadequacy can be traced in irregular or oscillating convergence patterns of the computed properties as functions of the increasing orbital set. In order to alleviate the above problems, we propose a procedure in which the orbital set is obtained by merging several separately optimized, and mutually non-orthogonal, orbital sets. This computational strategy preserves the advantages of capturing electron correlation on the total energy through the variational MCDHF method and allows to target efficiently the correlation effects on the considered property. The orbital sets that are merged are successively orthogonalized against each other to retain orthonormality. The merged orbital set is used to build CSFs that efficiently lower the energy and also adequately account for the correlation effects that are important for the property. We apply the procedure to compute the hyperfine structure constants for the 1s22s2S1/2 and 1s22p2P1/2,3/2o states in 7Li and show that it leads to considerably improved convergence patterns with respect to the increasing orbital set compared to standard calculations based on a single orbital set, energy-optimized in the variational procedure. The perspectives of the new procedure are discussed in a broader context in the summary.