bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatial Biodiversity of Birds in Land Covers of Wetlands on Jakarta’s North Coast
Authors: Andriwibowo  , Basukriadi Adi , Nurdin Erwin
Published: February 2023

Wetlands are suitable habitats for the coastal bird community. One of the important wetlands is located on Jakarta’s North Coast. Here, this study aims to assess the spatial biodiversity of birds in various land covers of wetlands on Jakarta’s North Coast. In total, there were 23 species belonging to 12 bird families. Ardeidae, Rallidae, and Silviidae bird families have more species compared to other families. The biodiversity H' values in the wetlands dominated by mangrove cover were the highest, at 2.527, followed by the wetlands having less mangrove cover and more water bodies and fish ponds only having H’ values equal to 1.811. The arboreal, small-to-medium-sized birds belong to Nectariniidae, Ploceidae, Silviidae, and Dicaeidae were widely distributed across all land cover. In contrast, the wetlands characterized by mangrove cover dominance combined with muddy substrate coasts were dominated by mid-large water birds belong to Anatidae, Scolopacidae, Ciconiidae, Rallidae, Ardeidae, Phalacrocoracidae, Anhingidae, and Alcedinidae. It is recommended to protect the mangroves and reforest the wetlands with mangroves to provide more habitats for the coastal bird community.
Review of the monograph by the team of authors a.p. Mintser, M.M. Potyazhenko, G.V. Nevoit ”Magnetoelectrochemical theory of metabolism. Conceptualization”, volume (2021)
Authors: Gulyar S.O.
Published: February 2023

Review of the monograph by the team of authors, MD, professor O.P. Mintser, MD, professor M.M. Potyazhenko, Candidate of Medical Sciences, associate professor G.V. Nevoit ”Magnetoelectrochemical theory of metabolism. Conceptualization. Volume 1” has been published. It was received from the Ukrainian scientist-physiologist, professor, Doctor of Medical Sciences Sergiy Olexandrovvch Gulyar. Professor S.O. Gulyar is one of the Ukrainian physiologists who studied the therapeutic effects of electromagnetic and magnetic fields on the human body, and he is a recognized expert in this scientific field. Professor S.A. Gulyar believes in this review that this monograph is of scientific and practical importance for medicine, since it significantly complements the existing system of medical knowledge. According to Professor S.A. Gular, this scientific work is one of the first attempts to generalize in a single logical system the existing fundamental knowledge regarding the electromagnetic physiology of the vital processes of the human body, medical and biological problems of transdisciplinarity and a systematic approach are considered for the first time in it, and this forms a new basis for understanding the human body - quantum. The e-book version can be found at the following links: http://repository.pdmu.edu.ua/bitstream/123456789/16848/1/MagnitoElectroChemicalTheoria_T1.pdf or http://surl.li/csjoj.
Radioelectronic wireless systems for non-invasive diagnostics of tubular bone fractures during body osteosynthesis
Authors: Kryvonosov V.Y. , Pavlov S.V. , Dudko O.G. , Yakymyuk D.I. , Shaiko-Shaikovsky O.G.
Published: February 2023

During the rehabilitation of the patient, accidental and shock loads are the main cause of aseptic loosening and damage to the elements of the fixing structure (FC). The lack of control over the formation of cartilaginous callus in the fracture zone causes an increase in the period of incapacity for work and an increase in material costs associated with the patient's stay in the hospital.The partial load on the bone is simulated, which is 25% of the calculated value and is equal to the average body weight of the patient. On the basis of the obtained data, a new method and device were developed for non-invasive detection of the initial moment of weakening or fracture of the fixing structure, detection of improper fracture fusion, diagnosis of the formation and control of cartilage callus growth, detection of the appearance of the initial moment of the inflammatory process in the patient's body and diagnosis of the causes of this process. The requirements for a possible method of non-invasive diagnosis of the condition of a tubular bone fracture are formulated. Criterion dependencies of the controlled parameters were established. The effect of random loads, which are the cause of failures of the fixing structure, has been proven. Wireless transmission of electricity and information made it possible to develop a method of non-invasive control and diagnosis of fracture of tubular bones and to establish criterion dependencies between controlled parameters. For a comprehensive diagnosis of the patient's recovery, it is sufficient to monitor the pressure at three points, the bending moment at the site of the bone fracture, the temperature of the periosteum and the temperature of any other point of the body.
Elaboraciones Freudianas y reflexión epistemológica: confluencias históricas y sistémicas
Authors: Betancourt Martínez Fernando
Published: February 2023

Ensayo donde la propuesta es que el psicoanálisis freudiano es una forma de ciencia que se puede validar por observaciones de segundo orden desde la teoría de sistema de Niklas Luhmann. Este ensayo oscila entre la elaboración de una teoría del sistema psíquico y las formas de validación del conocimiento psicoanalítico. No debemos olvidar que Luhmann construyó una teoría de la sociedad y consideró a la conciencia (el individuo) como entorno de ésta. Si por conciencia entendemos aparato psíquico, podemos valorar el esfuerzo que significa hacer una teoría de este sistema. Pues mientras el sistema social se reproduce autopoiéticamente por medio de la comunicación, en cambio el psíquico lo hace por medio de la represión. Siempre y cuando por represión se entienda generación de lo latente.
François Hartog, la historia y el "presentismo" del presente
Authors: Durán R. A. Norma
Published: February 2023

Ensayo sobre François Hartog donde se plantea un estado de la cuestión que expone el surgimiento de la historia-ciencia en el siglo XIX. En la segunda parte se presenta el trabajo que ha hecho François Hartog por historizar las prácticas, objetos y discursos del historiador desde la Antigüedad clásica hasta nuestros días. Su particular escritura y el estilo cuidadoso de su prosa nos coloca siempre a dos tiempos, en un juego de ires y venires, entre la historia antigua y la moderna. Hartog lo hace siempre desde la historia; no se vale de conceptos de la filosofía ni de otra disciplina en sus explicaciones, lo que permite ver la sutileza y la compleja capacidad de su lectura para captar cualquier inflexión o cambio de tono en la historicidad de los textos. Su amplia erudición le permite moverse a través de todos los periodos de la historia, lo que le posibilita elaborar comparaciones impensables para cualquier historiador especialista únicamente de su periodo. Su particular forma de leer lo llevó, desde la década de 1990, a buscar las combinaciones de otras temporalidades en la elaboración de la historia occidental.
¿En el umbral de una nueva teoría de la historia? Algunas reflexiones desde América Latina
Authors: Zermeño Guillermo
Published: February 2023

Reflexiones sobre teoría de la historia aterrizadas en el panorama de América Latina. Se destaca la figura señera de Edmundo O’ Gorman, quien abrió una reflexión sobre la historia en México. Después de esta aislada reflexión, la recepción de obras que problematizan el conocimiento histórico ha venido en aumento, pese a las resistencias de la historiografía más conservadora. También se abordan los problemas de las relaciones entre norte y sur en el sentido de que el discurso historiador latinoamericano contempla ese imaginario nacional que es atravesado por "un sentido peculiar del tiempo -el de la modernidad con su noción de progreso- que va paralelo a la profesionalización de la historia y a la formación de la nación. El ensayo concluye con la síntesis de lo que se considera el recorrido de la historia, desde el siglo XIX hasta al momento en que la historiografía hace un cierre sobre sí misma, a la vez que se considera la realización de "una especie de diccionario histórico-conceptual de dichas transformaciones semánticas" como una forma de plasmar un tipo de "teoría de la historia".
Pengaturan MicroRNA pada Penuaan dan Kanker
Authors: Ekowati Ana Lucia , Telium Havian Daulung
Published: February 2023

Masalah penuaan merupakan masalah global karena jumlah populasi orang lanjut usia di dunia terus meningkat. Untuk mengatasi masalah penuaan, perlu dilakukan penatalaksanaan kehidupan para lansia supaya memiliki kualitas hidup yang baik dan sehat. Penuaan merupakan kondisi terkait penurunan fungsi fisiologis dan disertai dengan berbagai penyakit degeneratif yang dapat meningkatkan kerentanan terhadap morbiditas dan mortalitas. Salah satu penyakit terkait penuaan yang prevalensinya cukup tinggi di Indonesia adalah kanker. MicroRNA (miRNA) merupakan non-coding RNA pendek (22 nukleotida) yang dapat mengatur ekspresi gen pada pasca transkripsi dengan mekanisme epigenetik. Dari berbagai penelitian yang telah dilakukan terbukti bahwa terjadi perubahan ekspresi miRNA tertentu yang terdapat pada sistem sirkulasi pada orang tua dan penderita kanker.  Hal ini dapat menunjukkan pengaturan miRNA pada penuaan dan kanker serta miRNA tertentu tersebut dapat dikembangkan sebagai biomarker penuaan dan penyakit kanker. Tujuan dari studi ini adalah memahami pengaturan miRNA pada penuaan dan kejadian kanker. Dari berbagai studi dapat disimpulkan bahwa miRNA mengatur ekspresi gen yang berperan dalam jalur persinyalan terkait penuaan dan penyakit kanker melalui beberapa hallmark penuaan yang kompatibel dalam patogenesis jenis kanker tertentu. Meskipun telah ditemukan beberapa kandidat miRNA terkait penuaan dan kanker, namun untuk sampai pada aplikasi miRNA sebagai biomarker masih terus dilakukan penelitian hingga saat ini.
Perbandingan Efektivitas Akupresur dan Prenatal Yoga Terhadap Penurunan Nyeri Punggung Bawah Ibu Hamil
Authors: Sari Yulia , Hajrah Wa Ode , Zain Venny Rafrianti
Published: February 2023

Latar belakang: Kejadian nyeri punggung bawah pada ibu hamil dapat menyebabkan nyeri kronik dan stress pada ibu hamil sehingga meningkatkan resiko terjadinya persalinan preterm. Dampak dari persalinan preterm adalah bayi lahir berat rendah, pertumbuhan janin terhambat, dan komplikasi kelahiran prematur bagi bayi. Tujuan: Penelitian ini bertujuan untuk mengetahui perbandingan efektivitas akupresur dan prenatal yoga terhadap penurunan nyeri punggung bawah ibu hamil. Metode: Penelitian ini menggunakan metode quasi experiment dengan two group pretest posttest design. Populasi penelitian ini adalah ibu hamil di Rumah Bersalin Zahira yang mengalami nyeri punggung bawah. Penentuan besar sampel dihitung menggunakan rumus uji hipotesis beda 2 mean, penentuan sampel dengan simple random sampling dan didapatkan masing-masing kelompok akupresur dan prenatal yoga 33 responden. Analisis data menggunakan Wilcoxon Signed Rank Test dan Mann- Whitney Test. Hasil: Penelitian menunjukkan uji rerata dalam tiap kelompok perlakuan menunjukkan hasil bermakna (p=0,0001) dengan selisih rerata penurunan intensitas nyeri punggung bawah pada kelompok akupresur sebesar 3,5 dan kelompok yoga sebesar 2,3. Simpulan: Teknik akupresur memiliki efektifitas lebih tinggi dibandingkan dengan prenatal yoga untuk menurunkan nyeri punggung bawah pada ibu hamil. Ibu hamil disarankan untuk menerapkan akupresur dan prenatal yoga dalam mengatasi nyeri punggung bawah serta perlu dilakukan penelitian lebih lanjut terkait faktor-faktor yang dapat mempengaruhi terjadinya nyeri punggung bawah pada ibu hamil.
Pyridoxine in isoniazid-induced psychosis
Authors: Yadav Renu , Kumar Manish , Kumar Niraj , Chacham Swathi
Published: February 2023

Isoniazid is a first-line drug for the management of tuberculosis. Recent changes in paediatric tuberculosis guidelines have insisted on a higher daily dose of isoniazid. Given the burden of paediatric tuberculosis in developing countries, it is pertinent that paediatricians are well versed with all possible adverse effects associated with isoniazid therapy and not just common ones like hepatotoxicity or peripheral neuropathy. Psychosis is one such rare adverse effect which has a reported incidence of 1%–2%. Here, we report a case of isoniazid-induced psychosis in a 4-year-old girl. The purpose of this report is to sensitise the paediatric healthcare community regarding this rare clinical entity along with highlighting the putative role of pyridoxine supplementation in the management of isoniazidinduced psychosis.
All-in-One Lower Eyelid Reconstruction after Skin Malignancies Removal: Combined Modified Tenzel Flap & Palatal Mucosal Graft
Authors: Romano Antonio , Sani Lorenzo , Troise Stefania , Orabona Giovanni Dell'Aversana , Abbate Vincenzo , Bonavolontà Paola , Committeri Umberto , Fusetti Stefano , Apolloni Federico , Iaconetta Giorgio , Califano Luigi
Published: February 2023

Lower eyelid reconstruction for defects greater than 50% is a much discussed topic in literature. The aim of this paper is to present an “all-in-one” surgical technique based on the combination of modified Tenzel flap and palatal mucosal graft to restore the anatomical integrity. In our paper we present a case report of 64 years old patient admitted in Maxillo-Facial Surgery Unit of Polyclinic Federico II of Naples in January 2020. He was affected by lower eyelid basal cell carcinoma, measuring 1.5 cm in diameter. He was treated removing full-thickness neoplasia, leaving a surgical gap of 2 cm. Reconstruction was performed using modified Tenzel flap to cover the skin gap and a palatal graft for the reconstruction of the tarsal region structural integrity. This "all-in-one" technique can handle full thickness eyelid defects with the advantage of respecting the dual layer eyelid structure without the need of a secondary surgical step. Moreover, has shown excellent results for both the preservation of eyelid competency and the low complications rate like ectropion and lagophthalmos.
KONCEPT GRAĐANINA U HRVATSKOM I JUGOSLAVENSKOM USTAVNOM PORETKU OD 1944. DO 1990. GODINE
Authors: Kosnica Ivan
Published: February 2023

The paper relates to the concept of citizen in the Croatian and Yugoslav constitutional orders from 1944 until 1990. The paper deals with the analysis of the most important constitutional acts that affected citizens starting from those enacted by the Yugoslav and Croatian authorities at the end of the Second World War and its aftermath. In addition, the paper conducts an analysis into the federal and republican constitutional law of 1953, federal and republican constitution of 1963 and federal and republican constitution of 1974. The paper sets forth that the authorities shaped the concept of citizen in line with the socialistic principles while at the same time gradually abandoning individual approach towards citizens. In addition, it is pointed out that socialistic constitutions emphasized class terminology in their constitutional texts and interests of the community over the individual interests. Furthermore, the paper indicates that in the constitutional acts, specifically those enacted in the aftermath of the Second World War and in the acts of 1974, the authority emphasized ethnic equality as an important feature of the constitution.
UVIDI U DJELOVANJE CIVILNOG DRUŠTVA U HRVATSKOJ U VRIJEME PANDEMIJE BOLESTI COVID-19
Authors: Baturina Danijel
Published: February 2023

The COVID-19 pandemic that started at the beginning of 2020 has put great constraints and significant challenges in organization of social and economic life. This paper analyses the civil society response to the COVID-19 pandemic and presents specific adaptations and opportunities to contribute to the society in the circumstances of the COVID-19 pandemic. The stories that civil society organizations published on the webpage ZADobroBIT.hr have been analysed by the means of a qualitative research. Thematic analysis in different scopes of activities shows that civil society organizations were more focused on the general population and various vulnerable groups. Vulnerable groups were recognized as those needing particular additional support in the course of this period. The activities aiming at general population focused on newly emerged needs related to civil protection. Civil society also worked on keeping the everyday routines in communities by conducting various types of activities. Informing and educating aimed at creating new and maintaining existing information and educational practices that adapted to pandemic circumstances. The results of the research show also that organizations have significantly changed, and quickly adapted their work with the help of technology and by using volunteer work. The results of the analysis suggest that civil society has proved flexible and able to respond quickly to emerging social needs, but also emphasized the contextual limitations of the actions. Thus, the paper discusses the position and role of civil society in the “new normal“, and the impact it has on its further development in the Croatian social and political environment.
DOPRINOS UČENJIMA O PRAVNIM IZVORIMA
Authors: Harašić Žaklina
Published: February 2023

One of the goals of this work is to point out the efforts of modern studies on the sources of law to reduce the traditional sources of law - material, ethical, formal and cognitive - to formal sources of law. It is argued that the concept of the source of law, which includes the mentioned types and the phenomena they contain, is too broad, and that these phenomena have only the fact that legal norms spring from them. Here, in our opinion, the problem arises as to how to consider the phenomena from which law undoubtedly arises, especially those that fall under the material and ethical types. The problem can be solved by calling material sources legal relations, and ethical sources legal values. In addition, there is another problem that many (formal) sources also have some material and/or ethical characteristics. Likewise, we pointed out the connection between legal sources and arguments, meaning by arguments regulations and what are usually considered arguments (a. a contrario, a. a simile ad simili, a. a fortiori). We proposed a possible list of legal sources, where the main problem is that, in compiling it, it is not possible to apply one (same) criterion.
Nervus intermedius: Microsurgical and anatomic relationships to the cerebellopontine angle neurovascular complex
Authors: Meybodi Ali Tayebi , Liang Allison S. , Mokhtari Pooneh , Moreira Leandro Borba , Zhao Xiaochun , Lawton Michael T. , Preul Mark C.
Published: February 2023

Background:

The nervus intermedius (NI) comprises fibers originating from the trigeminal, superior salivary, and solitary tract nuclei, which join the facial nerve (cranial nerve [CN] VII). Neighboring structures include the vestibulocochlear nerve (CN VIII), the anterior inferior cerebellar artery (AICA), and its branches. Microsurgical procedures at the cerebellopontine angle (CPA) benefit from understanding NI anatomy and relationships, especially for the microsurgical treatment of geniculate neuralgia, where the NI is transected. This study sought to characterize common relationships between the NI rootlets, CN VII, CN VIII, and the meatal loop of AICA at the internal auditory canal (IAC).

Methods:

Seventeen cadaveric heads underwent retrosigmoid craniectomy. Following complete unroofing of the IAC, the NI rootlets were individually exposed to identify their origins and insertion points. The AICA and its meatal loop were traced to assess their relationship with the NI rootlets.

Results:

Thirty-three NIs were identified. The median number of NI rootlets was 4 per NI (interquartile range, 3–5). The rootlets mainly originated from the proximal premeatal segment of CN VIII (81 of 141, 57%) and inserted onto CN VII at the IAC fundus (89 of 141, 63%). When crossing the acoustic-facial bundle, the AICA most frequently passed between the NI and CN VIII (14 of 33, 42%). Five composite patterns of neurovascular relationships were identified regarding NI.

Conclusion:

Although certain anatomical trends can be identified, the NI has a variable relationship with the adjacent neurovascular complex at the IAC. Therefore, anatomical relationships should not be used as the sole method of NI identification during CPA surgery.
Endoscopic transventricular approach for the resection of a hemorrhagic cavernous malformation of the tectal plate: Operative video
Authors: Ferlendis Luca , Capelli Sergio , Bossi Bianca , Barillot Cedric , Veiceschi Pierlorenzo , Locatelli Davide
Published: February 2023

Background:

Cavernomas of the third ventricle are rare entities that provide significant therapeutic challenges. Because of the better view of the surgical field and the possibility to achieve a gross total resection (GTR), microsurgical approaches are more commonly used to target the third ventricle. Endoscopic transventricular approaches (ETVA), on the other hand, are minimally invasive procedures that can afford a straight corridor trough the lesion, avoiding bigger craniotomies. Moreover, these approaches have shown lower infectious risks and shorter hospitalization times.

Case Description:

A 58-year-old female patient accessed the Emergency Department complaining of headache, vomiting, mental confusion, and syncopal episodes for the past 3 days. An urgent brain computed tomography scan revealed a hemorrhagic lesion of the third ventricle, conditioning triventricular hydrocephalus, so an external ventricular drainage (EVD) was placed in an emergency setting. An magnetic resonance imaging (MRI) showed a 10 mm diameter hemorrhagic cavernous malformation originating from the superior tectal plate. An ETVA was performed for the cavernoma resection, followed by an endoscopic third ventriculostomy. After proving shunt independence, the EVD was removed. No clinical nor radiological complications were assisted in the postoperative period, so the patient was discharged 7 days after. The histopathological examination was consistent with cavernous malformation. An immediate postoperative MRI showed GTR of the cavernoma with a little clot around the surgical cavity, which appeared completely reabsorbed 4 months later.

Conclusion:

ETVA provides a straight corridor to the third ventricle, excellent visualization of the relevant anatomical structures, safe resection of the lesion, and treatment of the concomitant hydrocephalus by ETV.
Traumatic rupture of intracranial dermoid cyst with continuous fat droplet migration
Authors: Aktham Awfa , Morita Shuhei , Takeuchi Satoru , Ismail Mustafa , Hoz Samer S. , Numazawa Shinichi , Watanabe Sadayoshi , Mori Kentaro
Published: February 2023

Background:

The intracranial dermoid cyst (ICD) can be complicated by rupture and spilling of its contents with potentially dreadful consequences. Head trauma as a predisposing element for this phenomenon is extremely rare. Few reports address the diagnosis and management of trauma-related rupture of ICD. However, there is a pronounced knowledge gap related to the long-term follow-up and the fate of the leaking contents. Here, we present a unique case of traumatic rupture of ICD complicated by continuous fat particle migration within the subarachnoid space with its surgical implications and outcome.

Case Description:

A 14-year-old girl had an ICD rupture following a vehicle collision. The cyst was located near the foramen ovale with intra and extradural extensions. Initially, we opted to follow the patient clinically and radiologically as she had no symptoms, and the imaging showed no red flags. Over the next 24 months, the patient remained asymptomatic. However, the sequential brain magnetic resonance imaging revealed significant continuous migration of the fat within the subarachnoid space, with the droplets noticed to increase in the third ventricle. That is considered an alarming sign of potentially serious complications impacting the patient’s outcome. Based on the above, the ICD was completely resected through an uncomplicated microsurgical procedure. On follow-up, the patient is well, with no new radiological findings.

Conclusion:

Trauma-related ruptured ICD may have critical consequences. Persistent migration of dermoid fat can be managed with surgical evacuation as a viable option to prevent those potential complications such as obstructive hydrocephalus, seizures, and meningitis.
The role of sirtuin 3 protein in the treatment of liver fibrosis
Authors: Гребнев Д.Ю. , Маклакова И.Ю. , Султанова Д.А.
Published: February 2023

Представлен обзор по НАД+-зависимой деацетилазе сиртуин-3 (SIRT3) - белке, обладающем антиоксидантной способностью, высокой метаболической активностью и потенциальной возможностью его использовании при лечении фиброза печени. Приводятся сведения о структуре, локализации и молекулярных мишенях SIRT3, обсуждаются механизмы воздействия SIRT3 на фиброз печени. В частности SIRT3 рассматривается как потенциальная терапевтическая мишень при лечении фиброза печени, однако данный аспект требует более детального изучения. В обзоре рассмотрены также механизмы нарушений в органах при подавлении активности SIRT3. Показана возможность приостановления развития фиброза и в других органах, таких как почки, легкие, сердце путем снижения уровня АФК и увеличения активности антиоксидантных ферментов через SIRT3-зависимые молекулярные пути.

The article presents a review of reports on NAD+-dependent deacetylase, Sirtuin-3 (SIRT3), as a protein with antioxidant capability, high metabolic activity, and a potential use in the treatment of liver fibrosis. Information about the SIRT3 structure, localization, molecular targets, and mechanisms of the action on liver fibrosis is provided. In the absence of effective treatment, continuous progression of liver fibrosis disturbs the normal structure and function of the liver, which can eventually lead to the development of cirrhosis. The mortality from cirrhosis as the terminal liver fibrosis ranks the 9th worldwide among all causes of death and the 6th among people of the most active working age. It has been demonstrated that oxidative stress caused by imbalanced formation and elimination of reactive oxygen species (ROS) is a trigger mechanism for hepatic fibrogenesis. Increased activity of certain antioxidant enzymes can suppress oxidative stress and, thus, delay the development of liver fibrosis. Studies have shown that the SIRT3 deficiency increases ROS and aggravates liver damage, while the SIRT3 activation contributes to attenuation of liver fibrosis. It was reported that SIRT3 may be a potential therapeutic target in the treatment of liver fibrosis, although this requires more detailed study. This review addresses the mechanisms of disorders in organs associated with the impaired SIRT3 activity. A possibility is shown to stop the development of fibrosis also in other organs, such as the kidneys, lungs, and heart, by limiting ROS and activating the antioxidant enzymes through SIRT3-dependent molecular pathways.
Stroke and probiotics
Authors: Пальцын А.А. , Свиридкина Н.Б.
Published: February 2023

Пробиота (микрофлора кишечника) - важный фактор возникновения, развития, лечения, реабилитации, формирования близких и отдаленных последствий инсульта. Поэтому можно и нужно использовать эти знания для профилактики и лечения этой распространенной и тяжелой, часто смертельной болезни. Важной медицинской характеристикой пробиоты является способность создавать короткоцепочечные жирные кислоты (short-chain fatty acids -SCFA) - энергетический субстрат для мозга и мышц, а также для «второго мозга» - колоноцитов. Для них они не только энергетический субстрат, но и стимулятор пролиферации. Флора, потребляющая SCFA препятствует колонизации кишечника патогенами, например, шигеллами и сальмонеллами, блокирует их адгезию к эпителию, стимулирует рост некоторых полезных анаэробных бактерий. Главный фактор пользы вегетарианской и веганской диеты - благоприятная пробиота.

Probiotics (intestinal microflora) are an important factor in the occurrence, development, treatment, rehabilitation, and formation of immediate and long-term consequences of stroke. Therefore, this knowledge can and should be used to prevent and treat this common and severe, often fatal, disease. An important medical characteristic of probiotics is the ability to create short-chain fatty acids (SCFAs), an energy substrate for the brain and muscles, as well as for the “second brain”, colonocytes. For them, SCFAs are not only an energy substrate, but also a proliferation inducer. The SCFA-consuming flora prevents colonization of the intestine by pathogens, such as shigella and salmonella, blocks the pathogen adhesion to the epithelium, and stimulates the growth of some beneficial anaerobic bacteria. A major benefit of vegetarian and vegan diets is favorable probiotics
Traumatic Atlantoaxial Rotatory Dislocation in Adult: Report of 10 Cases
Authors:   Department of Radiology, Burns and Trauma Center, Ben Arous, Tunisia, M Boukoucha , A Chérif ,   Department of Radiology, Burns and Trauma Center, Ben Arous, Tunisia, H Loukil ,   Department of Radiology, Burns and Trauma Center, Ben Arous, Tunisia, R Ben Khelifa ,   Department of Radiology, Burns and Trauma Center, Ben Arous, Tunisia, A Daghfous ,   Department of Radiology, Burns and Trauma Center, Ben Arous, Tunisia
Published: February 2023

The AARD is related to an extreme rotation of the cervicaloccipital hinge following an accidental distraction of the spine. It often occurs in children related to ligament laxity of the cranio-spinal junction. It is rarely encountered in adults, in general, in a context of violent trauma causing a ligament injury. Only about 20 cases have been reported in the literature [1]. The particularity of this entity is its purely rotatory mechanism, which is often without an associated bone fracture. A situation that can make diagnosis difficult and require a trained physician for clinical and radiological diagnosis. The purpose of this review is to help the young orthopedics and radiologists understand this entity, become familiar with the imaging appearance in CT and discuss patient care procedures.
Extensor Mechanism-Sparing Technique for Management of Proximal Tibia Sarcoma Resection: A Case Series Study
Authors:   Division of Skeletal Muscle Oncology Surgery, National Cancer Institute G. Pascale Foundation, IRCCS, Naples, Italy, F Fazioli , C Ruosi ,   Orthopaedic Unit, Department of Public Health, School of Medicine “Federico II” University, Naples, Italy, G Colella ,   Ospedale Santobono UOC Ortopedia e Traumatologia, Naples, Italy, M Gallo ,   Division of Skeletal Muscle Oncology Surgery, National Cancer Institute G. Pascale Foundation, IRCCS, Naples, Italy, F de Nigris ,   Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, Naples, Italy
Published: February 2023

The proximal tibia is one of the most challenging anatomic sites for resection of large bone tumors, due to the vicinity of the extensor mechanism. Here, we report outcomes of a novel radical resection technique which preserves the extensor apparatus. 8 patients were operated between 2001 and 2011 for large sarcomas with high-grade tibial localization. Six were giant cell tumor of bone histology (GCTB; defined as severe bone destruction and soft tissue extension) and two chrondrosarcoma at surgical grade G1, but with double localization in tibia and femur. Primary bone tumors and recurrences were treated with novel multiplanar resection technique avoiding removal of the tibial tuberosity and the patella tendon insertion, preserving extensor mechanism. In all cases, curettage and borage were not indicated due to extensive lesion size. Radical resection of the lower extremity (2 femurs and 8 tibias) yielded wide margins (R0) and patients were evaluated at 10 years of follow up. The average post operative Musculoskeletal Tumor Society (MSTS) score was 26.87 points (range: 23-29). All patients reached full passive and active extension and the maximum active flexion was 108.75° (range: 90°-120°). At the last follow-up (mean: 121.8 months), all patients and implants survived; no local infection, recurrence, metastasis, or relevant complications occurred. This surgical technique therefore appears to provide a safe treatment option when wide surgical margins are possible, and preserving the integrity of the extensor mechanism may improve the clinical outcome.
Mirrored Aneurysmal Bone Cyst Around the Knee
Authors:   Department of Traumatology and Orthopedics, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco, M Boussaidane , J Boukhriss ,   Department of Traumatology and Orthopedics, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco, B Chafry ,   Department of Traumatology and Orthopedics, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco, D Benchebba ,   Department of Traumatology and Orthopedics, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco, M Boussouga ,   Department of Traumatology and Orthopedics, Military Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, University Mohammed V, Rabat, Morocco
Published: February 2023

The aneurysmal bone cyst is a benign pseudotumor that often arises off the center of the long bones metaphysis and which as it grows can blow out the bone. The most widespread etiopathogenic theory is that of a reaction process to a venous malformation but the neoplastic theory is currently being discussed since the discovery of the translocation t (16; 17) (q22; p13) which is recurrent in primary aneurysmal cysts. We report here the case of a 26-year-old patient without medical history, who consults for pain in the right knee with partial functional impairment. The radiological assessment showed an osteolytic mirror image at the metaphyseal level of the lower end of the femur and the upper end of the tibia with thinned cortices exposing the high risk of fracture (Figure 1). A biopsy made confirms the diagnosis of the aneurysmal cyst. The patient underwent curettage with bone grafting.
Metal Tension-Band Wires vs Tension-Band Sutures in the Fixation of Olecranon Fractures: A Systematic Review
Authors:   FY1 Doctor, Ashford and St Peter’s Hospital NHS trust, UK, R Shaunak , A Dadrewalla ,   Final Year Medical Student, Imperial College NHS Trust, UK, V Sinha ,   Final Year Medical Student, King’s College Hospital NHS Trust, UK, S Raj ,   FY1 Doctor, University Hospitals Coventry & Warwickshire NHS Trust, UK, R Clay ,   FY1 Doctor, King’s College London, UK, S Ramji ,   FY1 Doctor, Liverpool University Hospitals Foundation Trust, UK, S Shaunak ,   Orthopaedic Surgeon, Department of Trauma and Orthopaedic Surgery, UK
Published: February 2023

Background: Tension-Band Wiring (TBW) is the treatment of choice for displaced, non-comminuted olecranon fractures. Due to the high complication rate involved with TBW, particularly the need for re-operative hardware removal, an alternate method using a high-strength, non-metallic Tension-Band Suture (TBS) construct has been precipitated. There is currently no literature comparing and evaluating these 2 particular techniques, therefore, this systematic review aims to address this. Methods: 6 databases were searched (MEDLINE, Embase, Web of Science, Cochrane Library, The CRD and Clinicaltrials.gov). Titles, abstracts and full articles were then systematically screened against the eligibility criteria. The primary outcomes studied were reported postoperative functional outcomes, and complication rates. Results: From 2538 identified abstracts, 5 studies met our eligibility criteria. Only one study compared TBW with TBS and concluded that in paediatric patients, there is a lack of benefit from TBS due to a similar rate of reoperation for hardware removal. 4 studies solely analysed TBW. In TBW, the rate of reoperation reached as high as 76.5% with the need for hardware removal being the most common indication. Conclusion: This review was required to highlight the alarming paucity of studies analysing TBS fixation in the treatment of non-comminuted olecranon fractures. Based on the included studies, it is difficult to conclude an advantage for either TBW or TBS due to the lack of standardised measuring of functional outcomes and comparative studies. There is potential for a reduced rate of reoperation in TBS, however, there is a great need for more robust studies analysing this technique.
Inept N2 Activation of Tri-Nuclear Nickel Complex with Labile Sulfur Ligands Facilitates Selective N2H4 Formation in Electrocatalytic Conversion of N2
Authors: Ray Anuj Kumar , Paul Ankan
Published: February 2023

Conversion of N2 to the energy vector N2H4 under benign conditions is highly desirable. However, such N2 fixation processes are extremely rare. It has been recently reported that N2 to N2H4 conversion can be achieved electrochemically by using a trinuclear [Ni3(S2C3H6)4]2- complex (named as [Ni3S8]2-). There are hardly any precedents of Nitrogen Reduction Reaction (NRR) by molecular catalysts having Ni and the highly unusual selectivity for N2H4 over NH3 makes this electrochemical reduction unique. A systematic theoretical study employing calibrated Density Functional Techniques to unearth the mechanisms of NRR (4e-/4H+) and HER (2e-/2H+) was conducted for the aforementioned trinuclear Ni complex. Our findings unravel a curious case of ligand lability working in tandem with metal centers in facilitating this unprecedented electrocatalytic activity. Furthermore, it is shown that the poor N-N bond activation property of Ni is responsible for this unusual selectivity. Additionally, the HER mechanistic pathways have also been delineated in this report. The mechanistic intricacies thus unearthed in this study may assist in developing more efficient electrocatalysts for N2H4 production through NRR.
Surfactant co-formulants in glyphosate-based herbicides: Detection and quantification in human urine
Authors: Jagani Ravikumar , Chen Jia , Yelamanchili Shirisha , Wolff Mary , Andra Syam
Published: February 2023

Polyethoxylated tallow amine (POEA) surfactants in glyphosate formulations are understudied. They may constitute greater health risks than glyphosate itself. Lack of validated biomarkers of exposure and metabolism, as well as analytical methods for measuring POEA, limit study of a formulations toxicity and associated risk. We report an exploratory analytical workflow using liquid chromatography coupled with a triple quadrupole mass spectrometer (LC-MS) in conjunction with neutral loss (NL) and product ion (PI) screening tools as an effective data acquisition tool to screen for POEA homologues in human urine. These features made it possible to find POEA at lower levels, which would not have been possible without screening tools and chemical standards.
Charge and Solvent Effects on the Redox Behavior of Vanadyl Salen-Crown Complexes
Authors: Nguyen Hien , Morgan Harry , Chantarojsiri Teera , Kerr Tyler , Yang Jenny , Alexandrova Anastassia , Leonard Nadia
Published: February 2023

The incorporation of charged groups proximal to a redox active transition metal center is an attractive strategy for altering redox behavior, installing electric fields, and enhancing catalysis. Vanadyl salen (salen = N,N-ethylenebis(salicylideneaminato)) complexes functionalized with a crown ether containing a non-redox active Lewis acidic metal cation (V-Na, V-K, V-Ba, V-La, V-Ce, and V-Nd) were synthesized. The electrochemical behavior of this series of complexes was investigated by cyclic voltammetry in solvents with varying polarity and dielectric constant (acetonitrile = 37.5; N,N-dimethylformamide = 36.7; and dichloromethane = 8.93). The vanadium(V/IV) reduction potential shifted anodically (>900 mV in acetonitrile and >700 mV in dichloromethane) with increasing cation charge as compared to complexes lacking the proximal cation. The reduction potential for all vanadyl salen-crown complexes measured in N,N-dimethylformamide was insensitive to cation charge magnitude, regardless of electrolyte or counter anion used. Titration studies of N,N-dimethylformamide into acetonitrile resulted in cathodic shifting of the vanadium(V/IV) reduction potential with increasing concentration of N,N-dimethylformamide. Binding constants of N,N-dimethylformamide (log(KDMF)) for the series of crown complexes show increased binding affinity in the order of V-La>V-Ba>V-K>(salen)V(O), indicating an enhancement of Lewis acid/base interaction with increase of cation charge. The redox behavior of (salen)V(O) and (salen-OMe)V(O) (salen-OMe = N,N-ethylenebis(3-methoxysalicylideneamine) was also investigated and compared to the crown-containing complexes. For (salen-OMe)V(O), a weak association of triflate salt at the vanadium(IV) oxidation state was observed through cyclic voltammetry titration experiments and cation dissociation upon oxidation to vanadium(V) was identified. These studies demonstrates the non-innocent role of solvent coordination and cation/anion effects on redox behavior.
The Indenyl Effect: Accelerated C-H Amidation of Arenes via Weakly-Coordinating Group Directed Nitrene Transfer Catalysis
Authors: Atkin Liselle , Priebbenow Daniel
Published: February 2023

Investigations into C-H amidation reactions using electron-deficient cationic half-sandwich d6 metal complexes revealed that the indenyl-derived catalyst [Ind*RhCl2]2 significantly accelerated the directed ortho C-H amidation of benzoyl silanes using 1,4,2-dioxazol-5-ones. Ring slippage involving a haptotropic rearrangement of the indenyl complex proposedly enables ligand substitution at the metal centre to proceed via associative, rather than dissociative pathways, leading to significant rate and yield enhancements. Intriguingly, this phenomenon appears specific for C-H amidation reactions involving weakly coordinating carbonyl-based directing groups with no acceleration observed for the corresponding reactions involving strongly coordinating nitrogen-based directing groups.
Fractional Charge Density Functional Theory and Its Application to the Electro-Inductive Effect
Authors: Kim Jun-Hyeong , Kim Dongju , Yang Weitao , Baik Mu-Hyun
Published: February 2023

We employed the chemical potential neutralization principle to demonstrate that fractional electrons are involved in the electro-inductive effect as well as the vibrational Stark effect. By the chemical potential model, we were able to deduce that the frontier molecular orbitals of immobilized molecules can provide valuable insight into these effects. To further understand and quantify these findings, we introduced fractional charge density functional theory (FC-DFT), a canonical ensemble approach for open systems. This method allows for the calculation of electronic energies, nuclear gradients, and the Hessian matrix of fractional electronic systems. To correct the spurious delocalization error commonly found in approximate density functionals for small systems, we imposed the Perdew-Parr-Levy-Balduz (PPLB) condition through linear interpolation of two adjacent integer points (LI-FC-DFT). Although this approach is relatively simple in terms of molecular modeling, the results obtained through LI-FC-DFT calculations predict the same trend seen in experimental reactivity and the frequency change of immobilized molecules.
Outlier-Based Domain of Applicability Identification for Materials Property Prediction Models
Authors: Panapitiya Gihan , Saldanha Emily
Published: February 2023

Machine learning models have been widely applied for material property prediction. However, practical application of these models can be hindered by a lack of information about how well they will perform on previously unseen types of materials. Because machine learning model predictions depend on the quality of the available training data, different domains of the material feature space are predicted with different accuracy levels by such models. The ability to identify such domains enables the ability to find the confidence level of each prediction, to determine when and how the model should be employed depending on the prediction accuracy requirements of different tasks, and to improve the model for domains with high errors. In this work, we propose a method to find domains of applicability using a large feature space and also introduce analysis techniques to gain more insight into the detected domains and subdomains.
PARISH LIFE IN THE KALININ DIOCESE IN 1950 ACCORDING TO CHURCH RECORDS AND IN THE MEMOIRS OF CONTEMPORARIES
Authors: Беговатов Дмитрий Александрович
Published: February 2023

В статье характеризуется приходская жизнь в Калининской епархии в начале 1950-х гг. на основе воспоминаний современников, годовых отчётов настоятелей, благочинных и управляющего епархией. Сопоставляется отражение различных аспектов приходской жизни в документах, выявляются проблемы и сложности в жизни религиозных общин, анализируются предложения по нормализации церковной жизни. Определяются факторы, влиявшие на посещаемость храмов, анализируется размер окладов духовенства, выявляются внутриприходские конфликты, рассматривается феномен самочинных требоотправителей и причины его распространения. Констатируется преимущество церковной отчётности перед воспоминаниями очевидцев в отношении точности деталей и полноты картины приходской жизни в Калининской епархии в середине XX в.

The article characterizes parish life in the Kalinin diocese in 1950 on the basis of the memoirs of the «children of war», annual reports of churches, deans and the Kalinin diocesan administration. The reflection of various aspects of parish life in sources is compared, problematic points in the life of religious communities are identified, proposals for the normalization of church life received «from the field» are analyzed. The advantage of church reporting over the memories of eyewitnesses in terms of the accuracy of details and completeness of the picture of parish life in the Kalinin diocese in the middle of the XX century is stated, the conclusion is made about the fundamental similarity of the evidence of the sources used and the need for their joint analysis.