bluuebunny/crossref_metadata_2025 huggingface dataset:
Pedagogija kao primjer neophodnosti interdisciplinarnog pristupa
Authors: Tomić Marija
Published: February 2025

U ovom radu analizirana je interdisciplinarnost kao sve popularniji pojam u naukama modernog doba. Rad navodi sve prednosti i mane ovog pristupa kroz suprotstavljena stanovišta različitih autora. Na primjeru pedagogije, kao jedne od društvenih nauka, objašnjena je potreba interdisciplinarnog pristupa problemima kao najadekvatnijeg puta istraživanja pedagoške stvarnosti. Interdisciplinarnost jeste fenomen koji sve više prostora zauzima u stručnim radovima posljednjih godina, ali ipak ne može da se tumači samo kao trend. Na osnovu konkretnih primjera, potkrijepljeno je stanovište o neospornoj važnosti interdisciplinarnosti, posebno u društvenim naukama. Ovaj problem je objektivno sagledan s obzirom na to da su navedeni i stavovi autora koji interdisciplinarnost smatraju naučno neutemeljenom pojavom. Kao rezultat detaljnog proučavanja, argumenti su zaključno na strani interdisciplinarnosti kao neophodnog pristupa pri izučavanju mnogih pojava.
Глобализација спорта: Улога Првог свјетског рата
Authors: Pajkić Aleksandar
Published: February 2025

Оснивање међународних спортских савеза, које је почело крајем 19. вијека, условљава усаглашавање и стварање јединствених међународних правила одређеног спорта, организовање система европских и свјетских такмичења и даљи развој и ширење спорта у свијету, чиме постепено долази до глобализације спорта. Поновним успостављањем Олимпијских игара 1896. доприноси се развоју организованог спорта у многим земљама свијета. Одржавање шестих Олимпијских игара у Берлину спријечио је Први свјетски рат. Иако је рат, као и у већини области, довео до стагнације у организованом спорту, поставља се питање да ли су спортски контакти, који су се догодили између народа у току рата, на одређени начин допринијели ширењу спорта и његовој даљој глобализацији након рата?
Кажњавање византијских владара: VII–XV вијека
Authors: Pantić Milutin
Published: February 2025

У раду се говори о казнама спроведеним над византијским царевима и престолонасљедницима. Основни циљ средњовјековних казни јесте да се појединцу нанесе физичко оштећење, чиме би му заувијек било онемогућено ступање на цариградски трон. Захваљујући византијским историчарима и хроничарима можемо видјети да се више царева суочило са насилном смрћу и суровим казнама, за разлику од оне мање групе владара чији је живот окончан природним путем. На основу статистике, од 88 царева, 37 је отишло мирним путем, 3 су изгубила живот несрећним случајем, 5 је погинуло у борбама, 30 је умрло од разних облика насиља и 13 се повукло у манастирске ћелије (Maleon, 2010: 9).
Sloboda volje kroz prizmu filozofije duha
Authors: Jurić Andrija
Published: February 2025

Autor u radu prikazuje problematiku slobode volje kroz filozofsku disciplinu filozofije duha. Kako bismo odgovorili na pitanje o budućnosti slobode, prvo moramo postaviti pitanje o mogućnosti slobode volje uopšte, posebno u svetlu savremenih otkrića na polju neuronauke. Ukoliko se um i svest, mentalna stanja uopšte, ispostave kao fizička, ona će neminovno postati i objekt determinističkog objašnjenja i redukcije. Determinizam kao svoj osnovni stav odbacuje postojanje alternativnih mogućnosti, čime budućnost ostaje „zatvorena“. Negirajući slobodu budućnosti, determinizam negira budućnost slobode. Ovaj rad će stoga ispitati neke od osnovnih svojstava i osobina fenomena svesti, kao što su Ja, opredmećivanje i raspolaganje, modelovanje alternativnih mogućnosti kao budućih stanja kauzalno-deterministički zatvorenog fizičkog sistema. Time bi se postavilo pitanje „otvorenosti“ svesti i za svest, bez narušavanja „zatvorenosti“ determinizma.
Слобода као мотив у дубровачким ренесансним и барокним драмама
Authors: Raca Jelena
Published: February 2025

Појам слободе представља једну од доминантних појава која је обиљежила стари Дубровник. Њен значај се одразио и на књижевност. Наиме, већ у самим почецима ренесансне књижевности, са првим појавама драме, осјетан је утицај и видљиво прожимање идеја слободе. Супротстављањем  Дубровника другим подручјима окупираним туђом влашћу, слобода је још више добијала на значају. Преко пасторала, а онда и чувених Палмотићевих мелодрама, „либертас“ је много заступљен. Тако се уочавају стихови проткани директном апотеозом и глорификовањем независности, уз изношење и родољубивих осјећања. Упоређујући ове двије књижевне епохе, занимљиво је пратити како се обликује, доживљава и слави независност, нарочито кроз мјешавину различитих драмских врста. Самим тим, основни циљ овог рада односи се на што боље доказивање и освјетљавање слободе, која је у суштини на прави начин представљала и цјелокупну Дубровачку републику.
POVEZANOST ADVERZIVNIH ISKUSTAVA IZ DJETINJSTVA SA NIVOOM DEPRESIVNOSTI I ANKSIOZNOSTI KOD STUDENATA
Authors: Davidoski Iva Patricia , Dobraš Tatjana , Petković Tamara
Published: February 2025

Adverzivna iskustva iz djetinjstva (ACE) podrazumijevaju stresne doživljaje (tokom prvih 18 godina života) koji imaju potencijal da prerastu u traume. Obuhvataju različite vrste zlostavljanja, zanemarivanja i porodične disfunkcije. Ranija istraživanja pokazuju da su ACE u vezi sa brojnim psihofizičkim problemima u odrasloj dobi. Ovo istraživanje se bavi ispitivanjem povezanosti kategorija adverzivnih iskustava iz djetinjstva s jedne strane, sa depresivnošću i anksioznošću kod studenata, s druge strane. Uzorak se sastojao od ukupno 115 ispitanika iz studentske populacije (80 djevojaka), starosti od 19 do 29 godina. Pored ACE kategorija, izmjeren je nivo depresivnosti (PHQ-9) i anksioznosti (GAD-7) ispitanika. Rezultati su pokazali da ukupni ACE skor pozitivno korelira i sa depresivnošću (r=.36, BF10>100) i s anksioznošću (r=.36, BF10>100). Na nivou pojedinačnih ACE kategorija, anksioznost najviše korelira sa vršnjačkom izolacijom (r=.40, BF10>100) i izloženošću nasilju u životnom okruženju (r=.28, BF10=12.12). Najviše korelacije sa depresivnošću imaju ACE kategorije: vršnjačka izolacija (r=.41, BF10>100) i zloupotreba supstanci u porodici (r=.28, BF10>12.66). Ovi nalazi pokazuju da je vršnjačka izolacija najbolji prediktor skorova anksioznosti i skorova depresivnosti. Anksioznost je više povezana sa adverzivnim faktorima iz spoljašnje sredine, dok je u slučaju depresivnosti prisutna veza sa kombinacijom adverzivnih faktora i izvan i unutar porodice.
ПРВИ БАЛКАНСКИ РАТ У СРПСКОЈ ДИГИТАЛИЗОВАНОЈ ПЕРИОДИЦИ И МУЛТИМЕДИЈАЛНОМ САДРЖАЈУ
Authors: Vidović Maja
Published: February 2025

У раду је представљена, компаративном методом, српска дигитализована периодика о почетку Првог балканског рата у Србији, за године 1912. и 2012, фокусирајући се на датум 6. октобар. На који начин су, српске новине, информисале јавност о почетку Првог балканског рата, у Србији? Шта се у данашњим новинама, на исти датум, писало стотину година послије Првог балканског рата? Како су о рату извјештавали новинари с почетка 20. вијека, те какву „слику“ имају новинари у данашње вријеме? У раду се користила доступна дигитализована штампа као што је „Политика“, „Правда“, „Пијемонт“ и „Српске новине“ из периода рата, те актуелне данашње новине „Политика“ „Време“ и „Данас“. Колико се, поред штампе, могло чути о стогодишњици Првог балканског рата, кроз мултимедијални садржај, као и о данас доступним емисијама које су биле посвећене рату? Компаративном методом покушали смо уочити на који начин је, средство јавног информисања, представило проблем Првог балканског рата. Покушали смо добити одговор на питање: „Колико је Балкански рат утицао на свијест код српског народа?“. Зашто је важно да говоримо о Првом балканском рату, у истој мјери, као што то чинимо и са Првим свјетским ратом? Дакле, имаћемо уопштену „слику“ историјског садржаја и начина како је Први балкански рат представљен у нама доступној дигитализованој периодици с почетка 20. и 21. вијека, као и у другим средствима, данашње, јавне информисаности.
PREVENTIVE AND REPRESSIVE METHODS OF COMBATTING CORRUPTION - GUIDEPOSTS OF THE NORMATIVE EXPERIENCES OF THE REPUBLIC OF SERBIA
Authors: Marina M. Simović  , Miomira P. Kostić
Published: February 2025

In this paper, the authors highlight the experience of the Republic of Serbia in standardizing preventive and repressive measures in the fight against corruption. That is why it is necessary to define the concept of corruption in a criminological sense, in a broader and narrower sense, and to indicate the measures of a preventive and repressive nature that are prescribed and improved in the Serbian legislation in order to fight against this phenomenon. It also points to the work of independent state bodies in the fight against corruption, as well as to the directed action of public policies in Serbia, through strategic and planning documents to combat this phenomenon, then to the guidelines for the temporal and substantive order of finding regulations, strategies, reports, planned actions and time agendas of actions of state bodies and independent institutions in the fight against corruption in Serbia. Therefore, normative-analytical and descriptive methods will be used when explaining the subject of research.
СТАНДАРД ОБРАЗЛОЖЕНОСТИ СУДСКЕ ОДЛУКЕ – ПРВИ ДИО - образложење у формалном и материјалном смислу -
Authors: Роберт Јовић
Published: February 2025

Судска одлука, независно од тога да ли се ради о првостепеној или одлуци виших судских инстанци, да би остварила своју примарну сврху (да ријеши предметну правну ствар) од есенцијалног значаја је да буде образложена у мјери да странкама буду видљиви разлози због којих је суд одлучио као у конкретном случају. На први поглед, оваква теоријска поставка у пракси не би требала да задаје било какве проблеме. Међутим, ситуација на „терену“ је све али не и једноставна и без проблема, примарно због квалитативног недостатка образложености судске одлуке. У том смислу, као проблем који на дугорочном плану може имати озбиљније посљедице и као такав латентно пријетити остварењу основне улоге сваке судске одлуке у поступку доношења правде, правосудна заједница и њене институције надлежне за едукацију судија су препознали потребу континуираног провођења семинара на којима би се, примарно новоизабраним судијама, од стране искусних судија указивало на значај добре образложености судске одлуке као и на примјере добре и лоше праксе са којима се едукатори сусрећу при припремању едукација на задану тематику. У овом раду, аутор ће кроз елаборирање о стандарду образложености судске одлуке покушати указати на значај његовог поштовања али и о конкретним ситуацијама у пракси које могу довести у питање законитост и правилност судске одлуке са аспекта необразложености или недостатне образложености.
МЕЂУНАРОДНИ КРИВИЧНИ СУД И ЊЕГОВА НАДЛЕЖНОСТ НА ТЕРИТОРИЈИ УКРАЈИНЕ И РУСКЕ ФЕДЕРАЦИЈЕ
Authors: Бојана Кнежевић
Published: February 2025

У овом раду, иако из његовог наслова произилази да ћемо се бавити искључиво мјесном надлежношћу, пажњу ћемо морати усмјерити на још неколико питања. Први разлог за то је што у овој ситуацији постоје многобројне специфичности којима треба да се позабавимо у циљу бољег разумијевања околности које су претходиле сукобу у Украјини. Пажњу треба усмјерити и на вишевјековни однос двије словенске државе, околности у којима је основан Међународни кривични суд, као и ранији привремени и интернационализовани судови, затим приступање Руске Федерације Римском статуту, али не и његовој ратификацији, те повлачењу потписа и посљедицама које то носи, будући да је Русија стална чланица Савјета безбједности. Даље, фокус је на дефинисању елемената кривичног дјела агресија у оквиру Римског статута и законодавства Украјине, те давању посебне изјаве од стране Украјине из новембра 2013. године, чиме је прихватила надлежност Међународног кривичног суда на својој територији за све случајеве који произађу из настале ситуације и обновила је 2014. године на неодређен период. Битно је поменути и дешавања у Белгородској области и питање имунитета у складу са чланом 98 Римског статута и изданим налогом за хапшење предсједника Руске Федерације.
Synovial macrophage diversity and activation of M-CSF signaling in post-traumatic osteoarthritis
Authors: Knights Alexander J , Farrell Easton C , Ellis Olivia M , Song Michelle J , Appleton C Thomas , Maerz Tristan
Published: February 2025

Synovium is home to immune and stromal cell types that orchestrate inflammation following a joint injury; in particular, macrophages are central protagonists in this process. We sought to define the cellular and temporal dynamics of the synovial immune niche in a mouse model of post-traumatic osteoarthritis (PTOA), and to identify stromal-immune crosstalk mechanisms that coordinate macrophage function and phenotype. We induced PTOA in mice using a non-invasive tibial compression model of anterior cruciate ligament rupture (ACLR). Single-cell RNA-sequencing and flow cytometry were used to assess immune cell populations in healthy (Sham) and injured (7 and 28 days post-ACLR) synovium. Characterization of synovial macrophage polarization states was performed, alongside computational modeling of macrophage differentiation, as well as implicated transcriptional regulators and stromal-immune communication axes. Immune cell types are broadly represented in healthy synovium, but experience drastic expansion and speciation in PTOA, most notably in the macrophage portion. We identified several polarization states of macrophages in synovium following joint injury, underpinned by distinct transcriptomic signatures, and regulated in part by stromal-derived macrophage colony-stimulating factor signaling. The transcription factors Pu.1, Cebpα, Cebpβ, and Jun were predicted to control differentiation of systemically derived monocytes into pro-inflammatory synovial macrophages. In summary, we defined different synovial macrophage subpopulations present in healthy and injured mouse synovium. Nuanced characterization of the distinct functions, origins, and disease kinetics of macrophage subtypes in PTOA will be critical for targeting these highly versatile cells for therapeutic purposes.
Reliable protein-protein docking with AlphaFold, Rosetta, and replica-exchange
Authors: Harmalkar Ameya , Lyskov Sergey , Gray Jeffrey J
Published: February 2025

Despite the recent breakthrough of AlphaFold (AF) in the field of protein sequence-to-structure prediction, modeling protein interfaces and predicting protein complex structures remains challenging, especially when there is a significant conformational change in one or both binding partners. Prior studies have demonstrated that AF-multimer (AFm) can predict accurate protein complexes in only up to 43% of cases.
1
In this work, we combine AlphaFold as a structural template generator with a physics-based replica exchange docking algorithm to better sample conformational changes. Using a curated collection of 254 available protein targets with both unbound and bound structures, we first demonstrate that AlphaFold confidence measures (pLDDT) can be repurposed for estimating protein flexibility and docking accuracy for multimers. We incorporate these metrics within our ReplicaDock 2.0 protocol
2
to complete a robust in-silico pipeline for accurate protein complex structure prediction. AlphaRED (AlphaFold-initiated Replica Exchange Docking) successfully docks failed AF predictions including 97 failure cases in Docking Benchmark Set 5.5. AlphaRED generates CAPRI acceptable-quality or better predictions for 63% of benchmark targets. Further, on a subset of antigen-antibody targets, which is challenging for AFm (20% success rate), AlphaRED demonstrates a success rate of 43%. This new strategy demonstrates the success possible by integrating deep-learning based architectures trained on evolutionary information with physics-based enhanced sampling. The pipeline is available at github.com/Graylab/AlphaRED.
Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner
Authors: Zhao Xin , Chae Yurim , Smith Destiny , Chen Valerie , DeFelipe Dylan , Sokol Joshua W , Sadangi Archana , Tschida Katherine
Published: February 2025

Social animals, including both humans and mice, are highly motivated to engage in social interactions. Short-term social isolation promotes social behavior, but the neural circuits through which it does so remain incompletely understood. Here, we sought to identify neurons that promote social behavior in single-housed female mice, which exhibit increased rates of social investigation, social ultrasonic vocalizations (USVs), and mounting during same-sex interactions that follow a period of short-term (3-day) isolation. We first used immunostaining for the immediate early gene Fos to identify a population of neurons in the preoptic hypothalamus (POA) that increase their activity in single-housed females following same-sex interactions (POA
social
neurons) but not in single-housed females that did not engage in social interactions. TRAP2-mediated chemogenetic silencing of POA
social
neurons in single-housed females significantly attenuates the effects of short-term isolation on social investigation, USV production, and mounting. In contrast, caspase-mediated ablation of POA
social
neurons in single-housed females robustly attenuates mounting but does not decrease social investigation or USV production. Optogenetic activation of POA
social
neurons in group-housed females promotes social investigation and USV production but does not recapitulate the effects of short-term isolation on mounting. To understand whether a similar population of POA
social
neurons promotes social behavior in single-housed males, we performed Fos immunostaining in single-housed males following either same-sex or opposite-sex social interactions. These experiments revealed a population of POA neurons that increase Fos expression in single-housed males following opposite-sex, but not same-sex, interactions. Chemogenetic silencing of POA
social
neurons in single-housed males during interactions with females reduces mounting but does not affect social investigation or USV production. These experiments identify a population of hypothalamic neurons that promote social behavior following short-term isolation in a sex- and social context-dependent manner.
The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2
Authors: Longhurst Adam D , Wang Kyle , Suresh Harsha Garadi , Ketavarapu Mythili , Ward Henry N , Jones Ian R , Narayan Vivek , Hundley Frances V , Hassan Arshia Zernab , Boone Charles , Myers Chad L , Shen Yin , Ramani Vijay , Andrews Brenda J , Toczyski David P
Published: February 2025

Progression through the G1 phase of the cell cycle is the most highly regulated step in cellular division. We employed a chemogenetic approach to discover novel cellular networks that regulate cell cycle progression. This approach uncovered functional clusters of genes that altered sensitivity of cells to inhibitors of the G1/S transition. Mutation of components of the Polycomb Repressor Complex 2 rescued proliferation inhibition caused by the CDK4/6 inhibitor palbociclib, but not to inhibitors of S phase or mitosis. In addition to its core catalytic subunits, mutation of the PRC2.1 accessory protein MTF2, but not the PRC2.2 protein JARID2, rendered cells resistant to palbociclib treatment. We found that PRC2.1 (MTF2), but not PRC2.2 (JARID2), was critical for promoting H3K27me3 deposition at CpG islands genome-wide and in promoters. This included the CpG islands in the promoter of the CDK4/6 cyclins CCND1 and CCND2, and loss of MTF2 lead to upregulation of both CCND1 and CCND2. Our results demonstrate a role for PRC2.1, but not PRC2.2, in antagonizing G1 progression in a diversity of cell linages, including chronic myeloid leukemia (CML), breast cancer, and immortalized cell lines.
Emergence of alternative stable states in microbial communities undergoing horizontal gene transfer
Authors: Hong Juken , Xue Wenzhi , Wang Teng
Published: February 2025

Microbial communities living in the same environment often display alternative stable states, each characterized by a unique composition of species. Understanding the origin and determinants of microbiome multistability has broad implications in environments, human health and microbiome engineering. However, despite its conceptual importance, how multistability emerges in complex communities remains largely unknown. Here, we focused on the role of horizontal gene transfer (HGT), one important aspect mostly overlooked in previous studies, on the stability landscape of microbial populations. Combining mathematical modeling and numerical simulations, we demonstrate that, when mobile genes only affect bacterial growth rates, increasing HGT rate in general promote the emergence of alternative stable states in complex microbiota. We further extend our analysis to scenarios where HGT changes interspecies interactions, microbial communities are subjected to strong environmental selections and microbes live in metacommunities consisting of multiple local habitats. We also discuss the role of different mechanisms, including interspecies interaction strength, the growth rate effects of MGEs, MGE epistasis and microbial death rates in shaping the multistability of microbial communities undergoing HGT. These results reveal how different dynamic processes collectively shape community multistability and diversity. Our results provide key insights for the predictive control and engineering of complex microbiota.
Review of models for estimating 3D human pose using deep learning
Authors: Salisu Sani , Danyaro Kamaluddeen Usman , Nasser Maged , Hayder Israa M. , Younis Hussain A.
Published: February 2025

Human pose estimation (HPE) is designed to detect and localize various parts of the human body and represent them as a kinematic structure based on input data like images and videos. Three-dimensional (3D) HPE involves determining the positions of articulated joints in 3D space. Given its wide-ranging applications, HPE has become one of the fastest-growing areas in computer vision and artificial intelligence. This review highlights the latest advances in 3D deep-learning-based HPE models, addressing the major challenges such as accuracy, real-time performance, and data constraints. We assess the most widely used datasets and evaluation metrics, providing a comparison of leading algorithms in terms of precision and computational efficiency in tabular form. The review identifies key applications of HPE in industries like healthcare, security, and entertainment. Our findings suggest that while deep learning models have made significant strides, challenges in handling occlusion, real-time estimation, and generalization remain. This study also outlines future research directions, offering a roadmap for both new and experienced researchers to further develop 3D HPE models using deep learning.
Closing the gap while standing still: clinimetric properties of a low-cost balance platform and a user-friendly app for posturography
Authors: Vredeveld Tom , Stins John F. , van Vliet Annelies J. , Tuinder Vincent C.M. , Ramaekers Stephan P.J. , Coppieters Michel W. , Pool-Goudzwaard Annelies L.
Published: February 2025

Background

The Wii Balance Board (WBB) is used as a rehabilitation tool for balance or strength interventions and posturography in balance tasks. Nonetheless, implementation of posturography using the WBB in a clinical setting is hampered by required technical skills for signal processing to obtain meaningful balance measures. Therefore, this study aims to evaluate the concurrent validity and test–retest reliability of a WBB to measure center of pressure (COP) parameters and to provide an easy-to-use web application to improve implementation of posturography in clinical practice.

Methods

A cross-sectional study was carried out including 30 healthy adults who performed repeated balance tasks including single and double leg standing still with eyes open or eyes closed. A WBB on top of a laboratory-grade force plate synchronously measured COP. Parameters based on COP displacement were calculated, including standard deviation of displacement, velocity, pathlength and 95% predicted ellipse area.

Results

The concurrent validity of the WBB to measure COP in quiet standing still tasks was excellent for all parameters (Intraclass Correlation Coefficient (ICC) > 0.900, p < 0.001), apart from medio-lateral velocity (ICC = 0.571, p = 0.090 to ICC = 0.711, p = 0.057). For the single leg balance tasks, across the two measurements, all WBB COP derived parameters showed excellent correlations with COP parameters derived from a laboratory-grade force plate (ICC > 0.95, p < 0.001). Test–retest reliability of the WBB was poor (ICC below 0.5) to occasionally good (ICC between 0.75 to 0.90) for the COP parameters from quiet standing balance tasks. Comparable reliability was found for the repeated measurements of single leg standing still. Power spectra analysis of both force plates revealed larger measurement error by the WBB in medio-lateral direction in tasks requiring minimal postural adjustments.

Conclusion

The WBB revealed excellent concurrent validity with a laboratory-grade force plate for balance tasks on a single leg or two legs for most COP parameters. The reliability was poor to moderate for most tasks, however comparable to the findings from the laboratory grade force plate. An open-source web application, employing R Shiny, was created to provide a tool to analyse COP parameters. Hereby, it was demonstrated that open-source scientific tools may help researchers to bridge the gap between scientific findings and clinical use of posturography.
Aplicação de controle Fuzzy em microgrids solares como auxilio na mitigação de interrupções em comunidades isoladas no Amazonas a Portaria Nº 140/2022
Authors: Silva Neto Oswaldo Wanderley da , Alencar David Barbosa de , Santos Eliton Smith dos , Brito Júnior Jorge de Almeida , Sanches Antonio Estanislau
Published: February 2025

Comunidades isoladas na Amazônia enfrentam desafios significativos no acesso a energia confiável devido a dificuldades logísticas e falta de infraestrutura. Microgrids fotovoltaicos surgem como uma alternativa potencial, mas sofrem com instabilidade e interrupções frequentes causadas pela variabilidade ambiental e pela complexidade de gestão dos recursos energéticos locais. Esta dissertação investiga a implementação do controle fuzzy nesses microgrids para mitigar falhas no fornecimento e melhorar a eficiência operacional, alinhando-se à Portaria nº 140/2022 do INMETRO. Essa abordagem busca aprimorar a confiabilidade e a sustentabilidade da energia, atendendo às diretrizes de qualidade e conformidade para sistemas fotovoltaicos. O estudo destaca o controle fuzzy como uma solução promissora para enfrentar os desafios energéticos em áreas remotas, apoiando o desenvolvimento socioeconômico e o progresso sustentável na Amazônia.
Gestão do Conhecimento: o uso de dashboards para processos licitatórios
Authors: Lichoveski Thiago Gabriel , Piana Janaina , Zola Fernanda Cavicchioli , Dias Marcelo Cappre , Alves Marcia Cristina
Published: February 2025

Considerando os estudos acerca da gestão do conhecimento (GC) existentes na literatura, observa-se que o compartilhamento eficiente de conhecimento, dados e informações por meio de tecnologias da informação é um fator comum para a otimização da GC organizacional. O presente estudo tem como objetivo analisar o uso de dashboards em processos administrativos e licitatórios. Para isso, foi realizado um estudo envolvendo o dashboard “Reu Adm” compartilhado entre os setores participantes dos processos licitatórios de uma Organização Militar (OM). A pesquisa foi embasada em um questionário aplicado junto aos agentes envolvidos em processos licitatórios da OM. Os resultados apontam que, apesar da necessidade de um esforço contínuo de aprimoramento técnico e educacional, a implementação do dashboard promoveu a otimização de fluxos de trabalho e simplificou rotinas administrativas. Os achados do estudo corroboram a literatura existente e evidenciam a contribuição direta dos dashboards para a eficácia da GC organizacional.
Impact of Nano-Urea Application on Wheat Yield and Soil Properties: A Sustainable Approach to Nutrient Management
Authors: Kumar Maneesh , Rai Sada Nand
Published: February 2025

A field experiment was conducted during the winter (rabi) season of 2022–23 at Dugurpur village Nuaon Block under On Farm Trial by Krishi Vigyan Kendra, Kaimur, to investigate the Impact of Nano-Urea Application on Wheat Yield and Soil Properties. The experiment was tested in a randomized block design with 2-nano-urea based treatment,viz. farmers practice  (100% RDF), 50% of RDN & 100% PK + nano urea @4ml/lt. water (Single spray at 35 DAS), 50% of RDN & 100% PK + 2 sprays of Nano Urea at (35 DAS) and (60-65DAS) @ 4 ml/lt water. Results revealed that, yield attributes were significantly higher with 50% RDN& 100% PK along with nano urea. This treatment also resulted in 1.6 and 4.2% more grain yield with 100% RDF (33.14 q/ha).The effective tillers/m2 and number of grains/spike whichresulted in significantly higher grain yield. Thus, 50% RDN  & 100% PK along with 50% of RDN & 100% PK + 2 sprays of Nano Urea at (35 DAS) and (60-65DAS) @ 4 ml/lt water are the more productive options for wheat-growingfarmers keeping view of the uprising cost and crisis of urea.
Complementary Feeding Practices among Mothers of Children Aged 6 to 59 Months in the Rural Commune of Sinder, Tillaberi, Niger
Authors: Djelifa HAMIDOU , Alio ALMOU ABDOULAYE , Zouleyhatou DODO HAMBALI , Ibrahim ALKASSOUM SALIFOU , Sadou HASSIMI
Published: February 2025

Adequate nutritional practices during early and early childhood are essential to ensure the growth, health and development of the full potential of these children (1). These practices begin with exclusive breastfeeding for the first six months of the child's life (2), then continue with complementary feeding while continuing breastfeeding up to two years or more (3). This study aims to assess the practices of complementary feeding by mothers and wet nurses in the rural commune of Sinder. This is a descriptive cross-sectional study, on a representative sample of mothers of children under five years old. A questionnaire was completed using a structured interview. The data were collected with ODK software and then analyzed with SPSS and Epi Info version 7.2 software. Simple random sampling method were used to determine the sample size. A total of 166 mother-child pairs were identified. Before the 6th month, the majority of children were introduced to complementary foods (55.56%), 44.44% of mothers gave complementary foods at the ideal time. The average age of introduction of complementary foods is 4.9±2.77 months. Children on complementary feeding represent about 38% and those on total ablactation about 62%. The average age of weaning was 17.2±4.67 months. The frequency of consumption of complementary foods (CF) varies from one to three times a day but the majority of children (55.56%) are fed two (2) times a day. Cereal-based foods were the most consumed. The minimum acceptable diet was not satisfactory for the majority of children.
Assessing Climate Change Resilience in Central Indian Agriculture: A Regional Indicators-based Approach and Agro-climatic Zone Mapping
Authors: Adhav Chaitanya Ashok , Singh Hari Nath
Published: February 2025

Climate change has adversely hampered the agricultural economy of India, especially central India. To get insight into the present level of climate change resilience in Central India (Madhya Pradesh, Maharashtra, Chhattisgarh, Southern UP) a composite climate change resilience capacity index (CCRCI) was developed for selected 102 districts using 50 climatic, soil, crop, livestock and socio-economic indicators in agriculture. Mann- Kendall non-parametric trend analysis was employed to evaluate long-term climatic trends (kharif 1981- summer 2023) for key climatic indicators like daily average temperature, precipitation, relative humidity and root zone soil wetness. Standard methodologies of index development like normalisation and principal component analysis (PCA) for weight assignment were executed. After developing CCRCI, agro-climatic zone-wise mapping was done for all the selected districts. Results revealed that Maharashtra had the largest number of high climate-resilience districts, followed by Madhya Pradesh with a mix of resilience levels in Chhattisgarh and Southern UP showing significant gaps in climate preparedness. The findings underscore the need for targeted interventions in low-resilience districts, particularly in agro-climatic Zones VII (Eastern Plateau and Hills Region) and IX (Western Plateau and Hills Region), where climate exposure and limited adaptability pose significant risks to agriculture. This mapping highlights the diversity of challenges and opportunities in central India, offering a framework for region-specific climate change resilience planning.
Molecular Profiling of Antibiotic-resistant Pseudomonas aeruginosa Isolated from Patients with Urinary Tract Infections in Rivers State University Teaching Hospital
Authors: Orokor Ordu, Wisdom , C.A. Mbata, , Pius Monsi Tombari
Published: February 2025

Background: Antibiotic-resistant Pseudomonas aeruginosa poses a significant challenge in urinary tract infections (UTIs), particularly in hospital settings.
Aim: The aim of this study was to analyze the molecular profile of antibiotic-resistant P. aeruginosa strains isolated from patients with urinary tract infections at the Rivers State University Teaching Hospital, Port Harcourt.
Methods: As part of a cross-sectional study, 199 patients were interviewed, and urine samples were collected from subjects with symptoms of a urinary tract infection. A semiquantitative urine culture method was used to detect significant bacteriuria. Suspected uropathogenic P. aeruginosa isolates were then identified using conventional and molecular techniques for identification and gene detection. The data generated from this study was presented as frequencies and percentages using Microsoft Excel 365.
Results: Of the 199 urine samples analyzed, P. aeruginosa was isolated in 17 cases, corresponding to a prevalence rate of 8.5%. Among the antimicrobial classes tested, aminoglycosides showed different resistance rates: amikacin (23.5%) and gentamicin (35.3%). Fluoroquinolones, including ofloxacin and ciprofloxacin, had resistance rates of 52.9%. Cephalosporins showed high resistance, particularly cefuroxime sodium (88.2%) and cefpodoxime (100%). Amoxicillin + clavulanic acid showed a resistance rate of 94.1%, while resistance to cefotaxime was 47.1%. Imipenem remained effective without resistance being observed. Several antimicrobial resistance indices (MAR) indices revealed complex resistance patterns across isolates, with the highest MAR index at 0.92. Genotypic analysis identified CTX-M as the most prevalent resistance gene (77.8%), followed by TEM (44.4%) and SHV (33.3%). Notably, no isolates harbored NDM or VIM genes, indicating the absence of carbapenem resistance genes among the studied isolates.
Conclusion: This study highlights the prevalence of antibiotic-resistant P. aeruginosa in UTIs at Rivers State University Teaching Hospital, the study also evaluated the antimicrobial susceptibility of Pseudomonas isolates, and key finding is the high resistance rates of the Pseudomonas isolates to multiple antibiotics, especially within the fluoroquinolone and cephalosporin classes, while maintaining susceptibility to Imipenem.
Efficacy of Botanicals as Biocontrol Agents Against Leaf Spot and Blossom Blight Pathogen of Marigold: A First Report from Longleng District of Nagaland, India
Authors: Behera Shubhendu Kumar , Kalita Hari Charan , Borah Sayanika , Ram Kalu , Kumar Avaneesh
Published: February 2025

Aims: To study about etiology and organic disease management strategies of Fusarium oxysporum induced blossom blight in marigold (Tagetes spp.), cultivated in and around Longleng district of Nagaland. The experiment aimed to formulate an effective organic disease management module to combat the disease and assess the efficacy of plant extracts and biocontrol agents in suppressing fungal growth.
Study Design: A completely randomized design (CRD) was employed for laboratory-based trials, and an exploratory survey was conducted during the winter season of 2024 to monitor disease incidence in marigold-growing areas around Longleng district of Nagaland.
Place and Duration of Study: Field survey has been carried out in Longleng district of Nagaland. All the laboratory works has been carried out in laboratory of Assam Agricultural University(AAU), Jorhat, Assam. Duration of research is 6 months.
Methodology: The tested phytoextracts at 10% and 20% concentrations included leaves of neem (Azadirachta indica), tulsi (Ocimum sanctum), garlic (Allium sativum), and other local plant species. Biocontrol agents such as Trichoderma viride, Trichoderma harzianum, and Pseudomonas fluorescens were collected from the rhizosperic soil of Marigold as well as from local fields and research institutions for evaluation. Disease incidence and severity were measured based on Percent Disease Intensity (PDI).
Results: The study demonstrated that garlic extract, at both tested concentrations, achieved complete inhibition (100%) of fungal growth. Additionally, several other plant extracts exhibited notable antifungal properties. Among the biocontrol agents, Pseudomonas fluorescens showed a strong antagonistic effect against Fusarium oxysporum (82.65%). These findings underscore the potential for incorporating phytoextracts and biocontrol agents into effective organic disease management strategies for marigold cultivation.
Conclusion: From the study, it is recommended to optimize the application of garlic extract, exploring its effectiveness in field conditions, and evaluating its potential in combination with other biocontrol agents or plant extracts.
Enhancement of Trap Catches of Melon Fruit Fly, Zeugodacus cucurbitae (Coquillett) by Gel Formulations of Protein Bait
Authors: Nithya K , Kavitha Zadda , Shanthi M , C.Vijayaraghavan  , Swarnalatha K
Published: February 2025

Fruit flies (Tephritidae: Diptera) are the devastating insect pests of quarantine importance and damage several vegetable crops particularly of Cucurbitaceae family in tropical, subtropical and temperate zones around the world. As capturing male fruit flies only does not bring desirable reduction in infestation levels, researchers are now focusing on female attractants. Among them, protein baits are prominent. Hence, an improved gel formulation of proteinex bait was tested in field conditions for attracting both the sexes of fruit flies. This study was conducted at Agricultural College and Research Institute, Madurai, Tamil Nadu during 2022. In bitter gourd, gel proteinex bait traps attracted more number of female fruit flies (319.90/trap/4 months) followed by liquid proteinex bait (228.02/trap/4 months). More number of male fruit flies was recorded in cue-lure traps (596.40/trap/4 months) followed by gel proteinex bait traps (291.78/trap/4 months). More female fruit fly catches in gel proteinex traps in bitter gourd indicated the requirement of more proteins for maturation of ovaries in females. Attraction of males to gel proteinex bait clearly showed the importance of protein sources for reproduction success of male fruit flies. Per cent incidence of cucurbit fruit fly was low in gel proteinex bait placed bitter gourd fields (64.18% reduction over control) than the fields in which liquid proteinex bait (49.29% reduction over control) and cue-lure (30.75% reduction over control) were placed. In gel proteinex bait experimental plots, reduction of cucurbit fruit fly incidence was more than the cue-lure. This is due to their high trap catches besides trapping more female fruit flies (602.92 male and female fruit flies as against 596.40 males in cuelure traps) which would have decreased the oviposition levels in the field.
Taxonomic Profile and Antimicrobial Potential of Brachybacterium conglomeratum VLCH–15 Isolated from Mangroves of Machilipatnam, Andhra Pradesh, India
Authors: Etta Kanya Kumari , Chetapalli Chiranjeevi , Muvva Vijayalakshmi , Kumbha Nagaraju
Published: February 2025

Actinobacteria of mangrove origin become a vital source of novel antibiotics with high therapeutic potential. Hence, the current study has been focused on antimicrobial potential of secondary metabolites produced by rare actinobacterium isolated from mangrove ecosystem of Machilipatnam, Andhra Pradesh, India. Sediment samples collected from mangrove habitats were shade dried at room temperature. The samples were employed for isolation of actinobacteria by serial dilution followed by spread plate method. Yeast extract malt extract dextrose (YMD) agar, starch casein agar (SCA), actinomycetes isolation agar (AIA) and humic acid vitamin agar (HV) media amended with NaCl @ 3% were employed for isolation of actinobacteria. A total of 15 actinobacterial strains were isolated and coded as VLCH-1 to VLCH-15. All the isolates were screened for their antimicrobial metabolite production against test bacteria and fungi. Out of 15 strains, VLCH-15 exhibited oad spectrum of antagonistic activity. Based on polyphasic taxonomic studies, the strain was identified as Brachybacterium conglomeratum VLCH-15. The growth curve and antimicrobial profile of B. conglomeratum VLCH-15were studied at regular intervals up to 10 days in batch culture. The secondary metabolites obtained from 7 days old culture showed high antimicrobial activity against X. campestris, E. coli and A. flavus. Among the fungi tested, Aspergillus flavus showed high sensitivity. Further studies on optimization, purification and characterization of bioactive metabolites of B. conglomeratum VLCH-15 are in progress. The bioactive compounds produced by this strain might have potential use in new antimicrobial therapy or drug design.
Ecofriendly Management of Aphids (Macrosiphoniella pseudoartemisiae) on Dawana (Artemisia pallens)
Authors: Pawar B.Y. , Gawade S.B. , Patil D.D. , Gaikwad R.T. , Shinde Sharmila
Published: February 2025

Artemisia pallens is an aromatic herb or shrub, Xerophytic in nature. The flowers are racemose panicles it belongs to the Asteraceae family. It is commercially cultivated for its fragrant leaves and flowers. It grows from seeds and cuttings and reaches maturity in four months. The plant is woody in the lower part of the stem. Dawana crops are mostly grown in Andhra Pradesh, Karnataka, Maharashtra and Tamil Nadu states in India. The aphids Macrosiphoniella pseudoartemisiae is the major pest of dawana in Maharashtra. Moreover the aphids are also major pest of Okra crop.
The pooled results indicated that among the treatments tested the treatment Lecanicillium lecanii @ 8 g/lit was significantly superior over all other treatments and found to be most effective by recording minimum survival of aphid population i.e. 13.13 aphids per tiller per plant after the first spray and 4.05 aphids per tiller per plant after second spray with 70.04% pest control and found at par with the treatment Metarhizium anisopliae @ 8 g/lit. Lecanicillium lecanii @ 8 g/lit.- recorded maximum fresh herbage yield i.e. 104.54 q/ha.
The Influence of Financial Performance on CSR in English League Football Clubs
Authors: Kusumawardhani Adhityawati , Hadinata Christian , Marchyta Nony Kezia
Published: February 2025

This research seeks to find out if there is a relationship between corporate social responsibility (CSR) and financial performance as measured by return on assets, debt equity ratio, and the current ratio. The primary focus of this work is on the 25 English Premier League clubs that were registered with the Charity Commission UK from 2018 to 2021. Corporate Social Responsibility (CSR) is the independent (explanatory) variable, while Return on Assets (ROA), Debt Equity Ratio (DER), and Current Ratio (CR) are the dependent variables. Regression multivariate modeling is the technique of choice. DER and ROA are found to positively influence CSR, while CR is found to have no impact. The report asserts that stronger clubs have higher financial social responsibility expenditures than weaker clubs. This research contributes new content on the subject of corporate social responsibility (CSR) in the field of sports with particular emphasis on football and provides important guidance to club managers on how to combine finance and CSR strategies.
Interpretation of Antibiotic Trials in Pediatric Pneumonia
Authors: Lipsett Susan C. , Hirsch Alexander W. , Bachur Richard G. , Neuman Mark I.
Published: February 2024

This cohort study assesses radiographic evidence of pneumonia and antibiotic use in children with clinically suspected community-acquired pneumonia.
School Vaccine Coverage and Medical Exemption Uptake After the New York State Repeal of Nonmedical Vaccination Exemptions
Authors: Correira John W. , Kamstra Rhiannon , Zhu Nanqing , Doll Margaret K.
Published: February 2024

Importance

Although New York State (NYS) recently adopted legislation eliminating nonmedical vaccination exemption options from school-entry requirements, the implications of the law for school vaccine coverage and medical vaccine exemption uptake have not been examined.

Objective

To evaluate the implications of the repeal of school-entry nonmedical vaccination exemptions for vaccine coverage and medical exemption uptake at NYS schools outside of New York City (NYC).

Design, Setting, and Participants

This cohort study had an interrupted time-series design and used generalized estimating equation models to examine longitudinal school immunization compliance data from the 2012 to 2013 through 2021 to 2022 school years. The cohort comprised NYS public and nonpublic schools, excluding NYC schools, with any students enrolled in kindergarten to 12th grade. Eligible schools had enrollment and immunization data before and after the implementation of the Senate Bill 2994A legislation. Data analyses were conducted in July 2023.

Exposure

Senate Bill 2994A was passed in June 2019, eliminating school-entry nonmedical vaccination exemptions. Since compliance with the law was evaluated for most students during the next school year, the 2019 to 2020 school year was considered to be the law’s effective date.

Main Outcomes and Measures

The primary outcomes were school vaccine coverage (defined as the percentage of students at each school who completed grade-appropriate requirements for all required vaccines) and medical exemption uptake (defined as the percentage of students at each school who received a medical exemption).

Results

Among the 3821 eligible schools, 3632 (95.1%) were included in the analysis, representing 2794 (96.9% of eligible) public schools and 838 (89.2% of eligible) nonpublic schools. The implementation of Senate Bill 2994A was associated with absolute increases in mean vaccine coverage of 5.5% (95% CI, 4.5%-6.6%) among nonpublic schools and 0.9% (95% CI, 0.7%-1.1%) among public schools, with additional annual increases in vaccine coverage observed through the 2021 to 2022 school year. The law’s implementation was also associated with a 0.1% (95% CI, 0.0%-0.1%) mean absolute decrease in medical vaccination exemption uptake at both public and nonpublic schools, and small but significant mean annual decreases in medical vaccination exemptions (0.02%; 95% CI, 0.01%-0.03%) through the end of the study period.

Conclusions and Relevance

Results of this cohort study suggested that repeal of school-entry nonmedical vaccination exemptions was associated with increased vaccine coverage at NYS schools outside of NYC. Coverage gains were not replaced by increases in medical vaccination exemptions.