bluuebunny/crossref_metadata_2025 huggingface dataset:
Transformasi Dalam Tradisi Bai’at Gadang Tarekat Syatariah Di Ponpes Nurul Yaqin Ringan-ringan
Authors: Pratama Yoga , Sukri Alvi
Published: January 2024

Bai’at gadang merupakan salah satu tradisi dalam tarekat syatariah yang melibatkan inisiasi spiritual dan komitmen pesertanya untuk mengikuti ajaran tarekat tersebut. Studi ini bertujuan untuk mengeksplorasi lebih luas tentang tradisi bai’at gadang tarekat syatariah serta melihat transformasi yang terjadi pada tata cara pelaksaan, makna dan peserta dalam acara yang dikakukan di Ponpes Nurul Yaqin Ringan-ringan tersebut. Melalui pendekatan kualitatif dan pengumpulan data melalui wawancara, observasi partisipatif, dan analisis dokumen, penelitian ini mengungkapkan aspek-aspek penting dari tradisi bai’at gadang. Temuan studi ini juga mengungkapkan bahwa bai’at gadang merupakan praktik turunan dari bai’at yang biasanya dilakukan dikalangan pengikut tarekat syatariah. Dalam perkembangannya praktik bai’at gadang mengalami transformasi dalam tiga bentuk: pertama, perubahan dalam tata cara pelaksaan seperti waktu, tempat dan manajemen. Kedua, perubahan dalam bentuk jumlah peserta. Ketiga, perubahan dalam bentuk makna. Studi ini memberikan wawasan mendalam tentang praktik keagamaan dan spiritualitas dalam konteks pesantren di Kabupaten Padang Pariaman. Penelitian ini juga dapat digunakan sebagai dasar untuk mengembangkan pemahaman lebih lanjut tentang tarekat syatariah dan tradisi bai’at gadang di kalangan akademisi, pemerhati agama, dan praktisi keagamaan.
Del prerromanticismo vivencial de José de Cadalso en sus Noches lúgubres (1789) al didactismo cuasi romántico de José Joaquín Fernández de Lizardi en sus Noches tristes y día alegre (1819)
Authors: Cantero García Víctor
Published: January 2024

La comprobación del distanciamiento de José Joaquín Fernández de Lizardi con respecto a los postulados prerrománticos presentes en las Noches lúgubres (1789), de José de Cadalso, era una de las cuestiones demandadas desde hace tiempo por la crítica literaria. Este es el propósito de la presente contribución: demostrar que el novelista novohispano se aleja en sus Noches tristes y día alegre (1819) del patrón narrativo de Cadalso y dota a su novela de señas de identidad propias. Nuestro estudio demuestra que Lizardi no sólo se libera de la tutela cadalsiana, sino que elabora un relato acorde con las intenciones didácticas y los principios morales que inspiran toda su obra literaria.
Jacinto Cenobio: génesis de una canción y de un personaje (con un comentario métrico-estilístico)
Authors: Paredes Alberto
Published: January 2024

El autor nos expone la genésis de una canción: "Jacinto Cenobio" partiendo de la memoria del propio cantautor Franscisco Javier Madrigal Toribio hasta los avatares de su grabación, fijación en la memoria colectiva y variantes de la misma, incluye la partitura y un análisis métrico y estilistico concienzudo.
Bibliografia zawartości pism „Dźwignia” (1927–1928) i „Miesięcznik Literacki” (1929–1931)
Authors: Czachowska Jadwiga
Published: January 2024

Wcześniej niepublikowana bibliografia autorstwa Jadwigi Czachowskiej zawartości dwóch bardzo ważnych dla przedwojennej lewicy literackiej czasopism, opatrzona wstępem samej autorki wyjaśniającym układ bibliografii oraz stosowane w nim skróty.
Zadania inteligencji. Współpraca Romana Jaworskiego z „Robotnikiem” w kontekście jego działalności publicystycznej
Authors: Szulik Weronika
Published: January 2024

Głównym celem artykułu jest przybliżenie współpracy Romana Jaworskiego (1883–1944) jako recenzenta literackiego i teatralnego z czasopismem Robotnik – organem Polskiej Partii Socjalistycznej – w 1933 roku, a ponadto osadzenie jej w kontekście całej działalności publicystycznej pisarza. Roman Jaworski wciąż pozostaje znany przede wszystkim ze swojego debiutanckiego zbioru opowiadań Historie maniaków (1910) i projektu groteskowej sztuki „trudnej i brzydkiej”. Jego role publicysty politycznego oraz recenzenta teatralnego zostały praktycznie zapomniane lub nie przypisuje się im dużej wagi. Tymczasem była to działalność nie tylko bogata, lecz także towarzysząca pisarzowi niemal przez całe życie, a co za tym idzie – odzwierciedlająca poszukiwania Jaworskiego najodpowiedniejszej opcji dla najpierw odzyskania niepodległości, później rozwoju i odbudowy nowego państwa. W artykule skupiam się na tekstach Jaworskiego, dodatkowo porównuję je z recenzjami Irzykowskiego – partnera i mentora pisarza od 1911 roku – pod kątem ich stosunku do polityki, sztuki i krytyki.
Between Saga and Enterprise: Anchoring Backwards and Striving Forwards
Authors: Mårtensson Katarina , Schrum Kelly
Published: January 2024

Introduction to Volume 12 of Teaching & Learning Inquiry.
From Private to Public: Using Authentic Audiences to Support Undergraduate Students’ Learning and Engagement
Authors: Hamilton Erica , Han Mihyun
Published: January 2024

The purpose of this article is to explore the use of authentic audiences in higher education to support undergraduate learning. To explore the results of integrating authentic audiences in higher education, we present a collective case study in which the use of authentic audiences was employed in separate undergraduate courses at two different higher education institutions in the Eastern and Midwestern United States (N = 75). In one case, Wikipedia was employed as an authentic audience and in the other case, experienced secondary educators as well as Twitter were embedded. The goal of implementing authentic audiences in both settings and courses was to increase student engagement and foster critical thinking. Results suggest that integrating authentic audiences through these means can enhance undergraduate students’ engagement and learning and may serve to capture, but not necessarily foster, students’ critical thinking. Concurrently, an instructor’s pedagogy must also align with tenets associated with authentic audiences, including a commitment to a co-construction of knowledge and the purposeful selection of authentic audiences who are engaged, willing to partner, and have the necessary expertise and resources to contribute to students’ learning.
KEBEBASAN EKSISTENSIAL MANUSIA DALAM NOVEL “SUNA NO ONNA” KARYA ABE KOBO
Authors: Galang Demo Satrio
Published: January 2024

Dalam kehidupan manusia sejak zaman dahulu hingga saat ini, tentu tidak akan pernah lepas dari hubungan antara masyarakat dengan karya sastra. Karya sastra merupakan refleksi pemikiran pengarang yang kerap kaitannya berupa pertanyaan, pernyataan sekaligus kritik. Karya yang betul-betul memiliki nilai untuk tetap eksis di dalam masyarakat akan terus hidup melampaui batas ruang dan waktu. Begitu juga dengan kesusastraan Jepang, banyak karya-karya sastra yang hingga kini masih dapat bertahan dan semakin menarik minat baca banyak orang. Hal itu dikarenakan kesusastraan Jepang yang memiliki ciri khas tersendiri dibandingkan negara-negara lain. Terlebih karya-karya penulis di era modern seperti Akutagawa Ryuunosuke, Kawabata Yasunari, yang karyanya telah diakui dan mendapatkan penghargaan Nobel Kesusastraan.Penelitian kali ini akan mengkaji novel yang berjudul Suna no Onna karya Abe Kobo yang terbit pertama kali pada tahun 1962. Penelitian ini menggunakan metode kualitatif atau pendekatan objektif, yang artinya pusat penelitian adalah pada teks itu sendiri. Hasilnya, terdapat permasalahan yang signifikan terkait dengan tema kebebasan, ketidakbebasan manusia ditinjau dari situasi cerita. Maka dari itu, penelitian ini akan memfokuskan pada konsep kebebasan manusia melalui peranan tokoh pria dalam novel Suna no Onna dengan menggunakan teori kebebasan manusia dalam filsafat eksistensialisme Sartre.
Since a long time ago, human life could not be separated with literary works. Literary works are the reflection of the writers’ thoughts, expressing their questions and critics towards life and society in general. The works that are considered to have a high societal value will carry on existing through space and time. This also applies in Japanese literature, which still survives up until now and attracts the reading interest of many people throughout the world. This is due to the certain characteristics Japanese literature has compared to other literary works throughout the globe. Moreover, the works of modern era author such as Akutagawa Ryuunosuke and Kawabata Yasunari have been recognized by the world and received Nobel Prize in literature.This study will analyze Kobo Abe’s Suna no Onna (1962) focusing on the concept on human freedom through the role of the male characters using human freedom theory in Jean Paul Sartre’s existentialism. This study applies qualitative method or objective approach, focusing on the text itself. The result is there are significant problems related to the theme of human freedom and elimination of human freedom in terms of story situation.
PERBANDINGAN KONSTRUKSI PEMBERITAAN KASUS KAUS BOM ATOM BTS DALAM MEDIA MASSA JEPANG ASAHI.COM DAN MAINICHI.JP
Authors: Adis Kusumawati
Published: January 2024

A popular boy group from South Korea BTS was being criticized because one of the member once wore a t-shirt with words and image graphic desgin that considered hurting the atomic bomb victims’ feeling. This controversy lead to a performance cancellation of theirs in a music broadcast “Music Station” aired by Asahi TV. This case gained attention from many countries especially Japan mass media. In this research, the writer uses news articles that published on November 9 to 10 2018 by online media Asahi.com and Mainichi.jp. This study applies qualitative research method approach and use discourse analysis proposed by Teun A. Van Dijk on the text dimension to determine the atomic bomb t-shirt related news being constructed by both newspapers. The result is there are some difference points between Asahi.com and Mainichi.jp in news constuction.
CITRA KOSMETIK DALAM IKLAN SHISEIDO “THE SECRET OF HIGH SCHOOL GIRLS”
Authors: Dita Ristanti
Published: January 2024

Image is an ideal picture of something. In commercial there are several types of images that are often displayed, including women's image, masculine image, luxury and exclusive image, social class image, pleasure image, benefit image, friendship image, and sexuality image. One example of a commercial that displays an image is a cosmetic commercial. The image displayed in general cosmetic commercial is the image of beauty through certain beauty criteria or standards. The image of beauty itself is classified as a form of women's image which illustrates that every woman always wants to look beautiful. In Japanese cosmetics commercial Shiseido "The Secret of High School Girls", to promote Shiseido women's beauty products using men as a model. The presence of female cosmetic commercial featuring men as a model made the writer interested in seeing how the image of cosmetics produced through the use of the male model. This study aims to analyze the image of cosmetics that appeared in Shiseido's cosmetic commercial "The Secret of High School Girls". This study uses qualitative research methods as a research method, and uses the method of documentation and literature in data collection. Documents in the form of pieces of scenes or scenes from Shiseido's commercial video "The Secret of High School Girls" were then analyzed using concepts such as the concept of advertising images and the concept of beauty of joshi kousei. The results of this study are 1) the image of Japanese beauty that is used as a standard of beauty by Shiseido is the beauty of joshi kousei who is portrayed as a young, fresh, and beautiful figure with maximum makeup; 2) the image of Shiseido's cosmetic benefits shown by the greatness of Shiseido's cosmetic products through the transformation process of turning men into joshi kousei.
Cultural Impact on Adolescent Behavior Advancing Health, Gender: A Scoping Review
Authors: Dewi Purnamawati  , Syamsulhuda Budi Musthofa  , Farid Agushybana
Published: January 2024

Background: Sexual and reproductive health is critical to the 2030 Sustainable Development Goals (SDGs). Various factors contribute to premarital sexual behaviour among adolescents, with culture being a pervasive influence in many countries. Adolescents in mountain communities are particularly vulnerable to engaging in premarital sexual behaviour. Aims: This review aims to explore research findings related to the cultural factors influencing premarital sexual behaviour among adolescents in general and specifically in mountain communities, contributing to the achievement of the SDGs. Method: This study employs a scoping review methodology. Search terms used in the articles include MeSH terms ["Adolescent" or "Teen"], ["Cultural impact" or "Cultural Role"], ["Premarital sex" or "Premarital sexual intercourses"], and ["Highland Communities" or "Mountain Communities"]. Databases utilised for article search include Science Direct, Proquest, and PubMed. Five journals published between 2019 and 2023 that meet the inclusion criteria were selected. Results: This review synthesises findings from 5 articles, narrowed down from an initial pool of 10,923 articles. All selected papers employ quantitative methods and originate from Ethiopia (3 articles), Nepal, and Tanzania. Conclusion: The review highlights the social, economic, and environmental influences on mountain communities, emphasising the cultural roles of alcohol consumption, social norms (customs), and family culture in shaping premarital sexual behaviour among adolescents. Education on the consequences of adolescent sexual behaviour is crucial, especially in cultures that tolerate such behaviours.
Determinants of Unintended Pregnancy in Central Java in 2022
Authors: Ardiningsih Eka Setya , Agushybana Farid , Shaluhiyah Zahroh
Published: January 2024

Background: Unintended pregnancy presents major challenges to maternal and child health. Despite extensive family planning initiatives in Indonesia, particularly in Central Java Province, the reduction in unintended pregnancies remains limited, from 13.5% in 2017 to 11.3% in 2022. A thorough comprehension of the issue based on target characteristics is essential for crafting effective targeted programs. Aims: This study aims to analyze the determinants of unintended pregnancy among women of childbearing age in Central Java Province. Methods: This study is non-reaction research utilizing secondary data analysis from the 2022 Family Data Update in Central Java Province. The research focuses on women of childbearing age (15-49 years) who are currently pregnant. Result: The prevalence of unintended pregnancies among women of childbearing age in Central Java Province is 11.3%. There is a significant association between age at first marriage (p=0.000), desired number of children (p=0.000), employment status (p=0.000), health insurance enrollment (p=0.000), contraceptive use in the last 12 months (p=0.000), maternal age (p=0.000), and education level (p=0.000) with unintended pregnancies. Women of childbearing age who marry before the age of 21, desire more than 2 children, are unemployed, enrolled in health insurance, have used contraception in the last 12 months, and aged over 35 are more likely to experience unintended pregnancies. Conclusion: The determinants of unintended pregnancies among women of childbearing age in Central Java Province include the age at first marriage, the desired number of children, employment status, health insurance enrollment, contraceptive use in the last 12 months, and maternal age.
Regulation and function of the RSK family in colorectal cancer
Authors: Wang Ziyi , Han Xiangming , Lei Zhe , Shi Chenxi , Wang Yuhong , Guo Lingchuan
Published: January 2024

P90 Ribosomal S6 Kinases (RSKs) constitute a class of Serine/Threonine (Ser/Thr) protein kinases and play a critical role as downstream targets in the Raf/MEK/ERK signaling pathway. Gaining insight into the biological function of RSK family proteins, given their functions in various tumors, is vital. The RSK family is involved in the regulation of cellular functions including cell proliferation, motility, invasion, and survival. The RSK family comprises four human isoforms (RSK1, RSK2, RSK3, and RSK4). The activation of RSK protein kinases is mediated through direct phosphorylation by extracellular signal-regulated kinase 1/2 (ERK1/2) and phosphoinositide-dependent kinase 1 (PDK1) after the Ras/MAPK (mitogen-activated protein kinase) pathway is activated. Recent evidence suggests that RSK family proteins promote the onset and metastasis of cancer, leading to the association of the protein expression of these kinases with various cancer types, such as colorectal cancer (CRC), breast cancer, lung cancer, kidney cancer, leukemia, esophageal squamous cell carcinoma, ovarian cancer, glioma, and endometrial cancer. In this review, we summarize the latest research on the RSK family, focusing on its role in patients with CRC, along with associated treatment challenges and limitations. This information enhances our comprehension of the regulation and function of RSK family proteins, highlighting their potential as both clinical biomarkers for diagnosing CRC and targets for molecular therapeutic interventions in the future.
35 years of lessons learned designing, building, and monitoring passive treatment systems for mining influenced water (part 1)
Authors: Gusek James J.
Published: January 2024

While natural processes have been remediating acidic water exhibiting elevated dissolved metals for eons, engineers and scientists have been trying to mimic nature in the treatment of mining influenced water for only about 50 years. The technical community has adopted the term “passive treatment” to describe the technology. The design of passive treatment systems is based on the application of multidisciplinary engineering sciences including biogeochemistry, hydraulics, physics, microbiology, and agronomics to name a few. Consequently, there are many opportunities to not quite “get it right” in passive treatment system design, construction, and operation. Fortunately, Mother Nature can be quite forgiving and sometimes a design or operational hiccup can reveal new insights. The case histories presented in this review reflect the learning experiences of a mining engineer whose technical education barely touched on the fundamentals of passive treatment system design. Early system designs were often based on the findings of other practitioners who were gracious enough to share their knowledge at pre-internet conferences and in easy-to-understand publications. Indeed, the current state of practice of passive treatment design rests on the shoulders of a few brilliant pioneers, most of whom are still with us. This review continues the sharing tradition. The common thread among the mini-case histories discussed is that most are from bench- and pilot-scale testing programs, which reinforces the benefits of small-scale testing as an economical way to accumulate valuable lessons learned experience with minimum risk.

Key takeaways from the lessons learned by this author are:● Biochemical reactors (BCRs) can be overloaded, but only for a short time to avoid permanent harm to the microbial community.● Other metal removal processes can substitute for sulfate reduction in overloading situations but the beneficial effects may be reversible.● Media material substitution risk in full scale construction can be lessened if bench or pilot data is available.● BCRs are feasible in cold climates.● The age of woody material (fresh vs . moldy) in BCR media is inconsequential.● Allow plants to grow on BCR surfaces with caution.● Excessive aluminum concentrations do not cause BCR media to plug.● Metal adsorption to manganese oxide coatings may be a viable alternative to sulfide precipitation in BCRs.● Mixing bypassed mining influenced water with BCR effluent may offer benefits in a freshet.● A test failure may be due to an improper design and should not condemn the passive treatment concept.● In final design and construction, avoid deviating from the bench- or pilot-scale test conditions.
Composition of Book Collections in Estates of the Smolensk Province (The Panin-Meshchersky Library)
Authors: Ladozhina T. N.
Published: January 2024

The purpose of the article is to introduce into scientific circulation new facts about the history of the formation of estate libraries in the Smolensk province using the example of the Panin-Meshchersky library in the Dugino estate in Sychevsky district. The work provides brief information about the owners of the library, for the first time presents the description of the composition of its collection, examines the further destiny of the collection and provides examples of books preserved in the collections of the Smolensk Regional Universal Scientific Library named after A. T. Tvardovsky, the library of Smolensk State University, etc. The source base for the study are published and unpublished materials: documents of the State Historical Museum, the Russian State Archive of Ancient Acts, rare books and scientific publication. The author comes to the conclusion that the library in Dugino has begonnen to be collected by its first owner Nikita Ivanovich Panin, further participation in the replenishment of this voluminous collection was taken by representatives of the Panin family Nikita Petrovich and Alexander Nikitich, and a large role in preserving and increasing this collection belongs to Nikolai Petrovich Meshchersky and his son Alexander Nikolaevich. It is shown that this library preserves the memory of not only its owners, but also their preferences, characters, and worldview. Using the example of the library of the Dugino estate, the prestige of family reading among the nobility, the purpose of which was self-development and self-education, becomes clearer. The nobles valued libraries, and their loss during the years of nationalization became a great family tragedy.
Bell's Theorem Begs the Question
Authors: Christian Joy
Published: January 2024

I demonstrate that Bell's theorem is based on circular reasoning and thus a fundamentally flawed argument. It unjustifiably assumes the additivity of expectation values for dispersion-free states of contextual hidden variable theories for non-commuting observables involved in Bell-test experiments, which is tautologous to assuming the bounds of ±2 on the Bell-CHSH sum of expectation values. Its premises thus assume in a different guise the bounds of ±2 it sets out to prove. Once this oversight is ameliorated from Bell's argument by identifying the impediment that leads to it and local realism is implemented correctly, the bounds on the Bell-CHSH sum of expectation values work out to be ±2√2 instead of ±2, thereby mitigating the conclusion of Bell's theorem. Consequently, what is ruled out by any of the Bell-test experiments is not local realism but the linear additivity of expectation values, which does not hold for non-commuting observables in any hidden variable theories to begin with.
Duality Principles and Numerical Procedures for a Large Class of Non-convex Models in the Calculus of Variations
Authors: Botelho Fabio
Published: January 2024

This article develops duality principles and numerical results for a large class of non-convex variational models. The main results are based on fundamental tools of convex analysis, duality theory and calculus of variations. More specifically the approach is established for a class of non-convex functionals similar as those found in some models in phase transition. Finally, in some sections we present concerning numerical examples and the respective softwares.
Series Hybrid Powertrains: Advancing Mobility Control in Electric Tracked Vehicle Technology
Authors: Çeliksöz Dersu , Kılıç Varlık
Published: January 2024

This work targets the development of a mobility control system for high-speed series hybrid electric tracked vehicles, which operate with independent traction motors for each track. The scope of the research encompasses the modeling of the series hybrid powertrain specific to military tracked vehicles, as well as an in-depth analysis of their dynamic behavior. Subsequently, the study conducts a critical review of the mobility control approaches sourced from literature, identifying key techniques relevant to high-inertia vehicular applications. Building on the foundational models, the study puts forward a robust closed-loop mobility control system aimed at ensuring precise and stable off-road vehicle operations. The system's resilience and adaptability to a variety of driving conditions are emphasized, with a particular focus on handling maneuvers such as steering and pivoting, which are challenging operations for tracked vehicle agility. The performance of the proposed mobility control system is tested through a series of simulations, covering a spectrum of operational scenarios. These tests are carried out in both offline simulation settings, which permit meticulous fine-tuning of system parameters, and real-time environments that replicate actual field conditions. The simulation results demonstrate the system's capacity to improve vehicular response and highlight its potential impact on the future designs of mobility control systems for the heavy-duty vehicle sector, particularly in defense applications.
Fractional-Order Load Frequency Control of an Interconnected Power System with Hydrogen Energy-Storage Unit
Authors: Wang Ping , Chen Xi , Zhang Yunning , Zhang Lei , Huang Yuehua
Published: January 2024

Modern power systems are confronted with a spread concern on the frequency stability issue due to the widespread integration of randomly fluctuating renewable resources. To address the above concern, this work introduces a load frequency control (LFC) scheme based on a hydrogen based energy-storage unit and a parameter tuning strategy for fractional-order proportional-integral-derivative (FOPID) controller. Firstly, a two-area interconnected power system (IPS) model, including thermal, hydro, solar, wind, gas power generator, and hydrogen based energy-storage unit, is established. Then, a FOPID controller is designed for this IPS model, and an improved gradient-based optimizer (IGBO) is developed to adaptively regulate the parameters of the FOPID controllers. Finally, the effectiveness of the offered LFC scheme are tested through load disturbance and renewable energy fluctuations test scenarios, and provides comparison and robustness analysis among different schemes. The test results validated that the offered LFC scheme can effectively suppress the frequency fluctuations of IPS and has excellent robustness.
Automatic Building Roof Plane Extraction in Urban Environments for 3D City Modelling Using Remote Sensing Data
Authors: Campoverde Carlos E. , Koeva Mila , Persello Claudio , Maslov Konstantin , Jiao Weiqin , Petrova-Antonova Dessislava
Published: January 2024

Mapping building roof plane structures is an active research direction in urban-related studies, as understanding roof structure provides essential information for generating highly detailed 3D building models. Traditional deep learning models have been the main focus of most recent research endeavours aiming to extract pixel-based building roof plane areas from remote sensing imagery. However, significant challenges arise, such as delineating complex roof boundaries and invisible boundaries. Additionally, challenges during the post-processing phase, where pix-el-based building roof plane maps are vectorized, often result in polygons with irregular shapes. In order to address this issue, this study explores a state-of-the-art method for planar graph reconstruction applied to building roof plane extraction. We propose a framework for reconstructing regularized building roof plane structures using aerial imagery and cadastral information. Our framework employs a holistic edge classification architecture based on an attention-based neural network to detect corners and edges between them from aerial imagery. Our experiments focused on three distinct study areas characterized by different roof structure topologies: Stadsveld – 't Zwering neighbourhood and Oude Markt area, located in Enschede, The Netherlands, and the Lozenets district in Sofia, Bulgaria. The outcomes of our experiments revealed that a model trained with a combined dataset of two different study areas demonstrated superior performance, capable of delineating edges obscured by shadows or canopy. Our experiment in the Oude Markt area resulted in building roof plane delineation with an F-score value of 0.43 when the model trained on the combined dataset was used. In comparison, the model trained only on the Stadsveld – 't Zwering dataset achieved an F-score value of 0.37, and the model trained only on the Lozenets dataset achieved an F-score value of 0.32. The results from the developed approach are promising and can be used for 3D city modelling in different urban settings.
Numerical Simulation of Cavitation Control around a Circular Cylinder Using Porous Surface by Volume Penalized Method
Authors: Sadri Maryam , Kadivar Ebrahim , El Moctar Ould
Published: January 2024

In this work, we conducted a numerical study on the cavitation flow around a circular cylinder through the implementation of a porous coating. The primary objective addressed the effectiveness of utilizing a porous surface to control cavitation. We analyzed the cavitation dynamics around the cylinder and the hydrodynamic performance at different permeability levels of the porous surfaces. The flow was governed by the density based homogeneous mixture model and the volume penalization method was used to deal with the porous layer. A high-order accurate numerical method was adopted for the simulation of the cavitating flow through solving the preconditioned multiphase equations. The results revealed that the application of porous layer led to effective suppression of the cavitation vortex shedding. In addition, a reduction of the shedding frequency was obtained which accompanied by thinner and elongated vortices in the wake region of the cylinder. With the proper porous layer, the inception of the cavitation on the cylinder was suppressed and the amplitude of pressure pulsations due to the cavitation shedding mechanism was mitigated.
Pituitary Adenoma in the Philippines: A Scoping Review on the Treatment Gaps, Challenges, and Current State of Care
Authors: Tabuzo Mykha Marie B. , Hernandez Mary Angeline Luz U. , Chua Annabell E. , Maningat Patricia D. , Chiu Harold Henrison C. , Jamora Roland Dominic G.
Published: January 2024

Pituitary adenomas are benign brain tumors that pose a heavy burden on patients worldwide. However, the local burden of disease is yet to be established due to scarcity of data. In line with this, this study aims to present the challenges and gaps in the treatment of pituitary adenomas in the Philippines. A scoping review of available relevant literature on epidemiology, clinical experience with treatment, health financing, and healthcare delivery system based on the Preferred Reporting Items for Systematic reviews and Meta-analysis guidelines extension for Scoping Reviews was conducted. The scarcity of updated local clinical data, inequity of distribution of resources, inadequate government support, and lack of affordable diagnostic testing, medications and neurosurgical procedures are the factors that hinder provision of adequate care of pituitary adenomas in the Philippines. There are notable treatment gaps in the management of pituitary adenomas in the Philippines, which may be addressed by strengthening universal healthcare. Strategies to address these gaps were proposed, including improving public-private insurance coverage, increasing manpower, enhancing accessibility to resources, and spreading more awareness.
Economic Policy Uncertainty’s Spatial Spillover Impacts on Green Economy Efficiency
Authors: Wang Tianli , Cao Biru , Li Ang
Published: January 2024

Green economy has emerged as a significant pillar of sustainable development in the current global context, and the unpredictability of economic policy has progressively garnered the interest of businesses and government officials as one of the obstacles they must confront. This paper examines how uncertainty in the green economy impacts the green economy's efficacy. The research concentrates on how changes in a particular region can result in geospatial diffusion (spatial spillover), which is a form of spatial spillover wherein the uncertainty of the green economy can impact its efficacy. This paper examines the policy formulation and current state of the green economy across various regions, as well as the diffusion of economic policy uncertainty across geographical areas and the subsequent impact on the green economy's status quo. There is a negative correlation between economic policy uncertainty and green economy efficacy, according to research. There is a spatial spillover effect between economic policy uncertainty and the efficacy of the green economy. Regional variations exist in the impact of economic policy uncertainty on the efficacy of the green economy. The findings indicate that the implementation of AI has a more substantial beneficial effect on carbon emissions. An increase in carbon dioxide emissions poses a growing challenge for the industrial sector in its pursuit of carbon neutrality.
Evaluation of Surrogate Aerosol Experiments to Predict Spreading and Removal of Virus-Laden Aerosols
Authors: Beimdiek Janis , Schmid Hans-Joachim
Published: January 2024

Estimating the infection risks in indoor environments comprises the assessment of the behavior of virus-laden aerosols, i.e. spreading, mixing, removal by air purifiers etc. A promising experimental approach is based on using non-hazardous surrogate aerosols of similar size, e.g. salt particles, to mimic the virus aerosol behavior. This manuscript addresses the issue how a successful transfer of such experiments can be accomplished. Corresponding experiments in two very different environments, a large community hall and a seminar room, with optional use of air purifiers in various constellations were conducted. While high particle concentrations are advantageous in terms of avoiding influence of background aerosol concentrations, it is shown that appropriate consideration of aggregation and settling are vital to theoretically describe the experimentally determined course of particle concentrations. A corresponding model equation for a well-mixed situation is derived and the required parameters are thoroughly determined in separate experiments independently. It is demonstrated that clean air delivery rates (CADR) of air purifiers determined with this approach may differ substantially from common approaches not explicitly taking into account aggregation.
Flood Forecasting Method and Application based on Informer Model
Authors: Xu Yiyuan , Zhao Jianhui , Wan Biao , Cai Jinhua , Wan Jun
Published: January 2024

Flood forecasting helps anticipate floods and evacuate people, but due to the access of a large number of iot data acquisition devices, the explosive growth of multidimensional data and the increasingly demanding prediction accuracy, classical parameter models and traditional machine learning algorithms are unable to meet the high efficiency and high precision requirements of prediction tasks. In recent years, deep learning algorithms represented by convolutional neural networks, recurrent neural networks and Informer models have achieved fruitful results in time series prediction tasks. The Informer model is used to predict the flood flow of the reservoir. At the same time, the prediction results are compared with the prediction results of the traditional method and the LSTM model, and how to apply the Informer model in the field of flood prediction to improve the accuracy of flood prediction is studied.
The data of 28 floods in the Wan 'an Reservoir control basin from May 2014 to June 2020 were used, with areal rainfall in five subzones and outflow from two reservoirs as inputs and flood processes with different sequence lengths as outputs. The results show that the Informer model has good accuracy and applicability in flood forecasting. In the flood forecasting with sequence length of 4, 5 and 6, Informer has higher prediction accuracy, and the prediction accuracy is better than other models under the same sequence length, but the prediction accuracy will decline to a certain extent with the increase of sequence length. The Informer model stably predicts the flood peak better, and its average flood peak difference and average maximum flood peak difference are the smallest. As the length of the sequence increases, the number of fields with a maximum flood peak difference less than 15% increases, and the maximum flood peak difference decreases. Therefore, the Informer model can be used as one of the better flood forecasting methods, and it provides a new forecasting method and scientific decision-making basis for reservoir flood control.
Enhancing Structural Diversity of Lathyrane Derivatives through Biotransformation by the Marine-Derived Actinomycete Streptomyces puniceus BC-5GB.11
Authors: Escobar-Montaño Felipe , González-Rodríguez Victoria E. , Macías-Sánchez Antonio J. , Botubol-Ares José M. , Durán-Patrón Rosa , Hernández-Galán Rosario
Published: January 2024

Lathyrane-type diterpenes have a wide range of biological activities. Among them, euphoboetirane A (1) exerts neurogenesis-promoting activity. In order to increase the structural diversity of this type of lathyranes to explore their potential use in neurodegenerative disorders, the biotransformation of 1 by Streptomyces puniceus BC-5GB.11 has been investigated. The strain BC-5GB.11, isolated from surface sediments collected from the intertidal zone of the inner Bay of Cadiz, was identified as Streptomyces puniceus, as determined by phylogenetic analysis using 16S rRNA gene sequence. Biotransformation of 1 by BC-5GB.11 afforded five products (3-7), all of them reported here for the first time. The main biotransformation pathways involved regioselective oxidation at non-activated carbons (3-5) and isomerization of the D12,13 double bond (6). In addition, a cyclopropane-rearranged compound was found (7). The structures of all compounds were elucidated on the basis of extensive NMR and HRESIMS spectroscopic studies.
Immediate Implant Placement at an Inflammatory Periapical Cyst Site in the Aesthetic Area
Authors: Perez Alexandre , Layac Mathilde , Lombardi Tommaso
Published: January 2024

A healthy 47-year-old woman consulted the Oral Surgery and Implantology Unit of the University Hospitals of Geneva with a request to treat her painful tooth 11 and replace the missing tooth 21. The dental history revealed that the patient had lost teeth 21 and 22 due to advanced caries. On clinical examination, tooth 11 showed an ill-fitting prosthetic crown with overhanging margins, an increased localized probing depth of 8 mm in the disto-vestibular area and sensitivity to percussion. The edentulous site 21 showed horizontal bone atrophy. Radiological examination revealed a well-defined unilocular radiotransparent lesion surrounded by a thin radiolucent border, located at the apex of tooth 11 and measuring 10 x 8 mm. The treatment consisted of extraction of 11, enucleation of the apical lesion, insertion of implants at sites 11 and 21 with simultaneous bone augmentation in a single surgical procedure with aesthetic and functional results at 3-year follow-up without any complications. Our case highlights that immediate implant placement in case of cystic periapical lesion represents a good valid alternative to standard treatment.
What is “Sclerotium nivale”? Old and new snow mold in Russia
Authors: Tkachenko Oleg , Babosha Alexander , Degawa Yousuke , Hoshino Tamotsu
Published: January 2024

It has been reported that Sclerotium nivale Elenev causes winter damage (Sclerotium disease) to winter rye and turfgrass in the European part of Russia, Ukraine, and Estonia. This fungal name is invalid, and their biological characteristics are limited. Since all reports on this fungus and their disease are written in Russian and Estonian without our recent review (Tkachenko 2013), few phytopathologists outside the former Union of Soviet Socialist Republics know about this fungus. We found symptoms of Sclerotium disease in Moscow, Russia, and we obtained asexual spore-forming ascomycetous (absent clamp connections) and basidiomycetous (had clamp connections) isolates from their white sclerotia. “S. nivale” was composed of several fungal species of ascomycetes and basidiomycetes. The ascomycetous isolate had the ability to grow under the snow cover, and phylogenic analysis suggested that the ascomycetous isolate had high homology (98–99%) with genera of Karstenula and Paraphaeosphaeria. We previously reported sclerotia of Typhula sp. were formed ca. 2 weeks to 1 month after the snow melt, remained immature as mycelial aggregations after snow melt, and matured without snow. In addition, Paraphaeosphaeria included sclerotium parasites such as P. minitans. Several cold-adapted fungi infected basidiomycetous sclerotia of Typhula spp. and others. These findings suggested that ascomycetous S. nivale was the possibility of the mycoparasite under the snow.
Electrochemotherapy in Kaposi’s Sarcoma Patients. From the Gold Standard Strategy to Locally Advanced Cutaneous and Subcutaneous Lesions.
Authors: Rullo Vincenzo , Castellaneta Francesco , D’Antonio Santolo , Rosa Anna De , Grieco Michele P. , Fabrizio Tommaso
Published: January 2024

Electrochemotherapy (ECT) is one of the newest therapeutic strategies employed as medical procedure for skin neoplasms’ treatment, especially for Classic Kaposi’s Sarcoma (CKS). The aim of this study was to demonstrate ECT clinical response and local control of CKS disease. Primary endpoint was to value the worth and efficacy of this local therapy in CKS skin lesions’ treatment. Nineteen CKS patients were enrolled, 14 males and 5 females with median age at diagnosis of 72. Complete response (CR) has been gained in 12 patients after first ECT attempt, meanwhile 3 and 4 out of 19 patients obtained a Partial response (PR), so that they underwent to a second and a third ECT treatment, each other. Clinical response was evaluated during all the time of the follow-up, which ranged between 3 months and 4 years with a median of 18 months. CKS skin lesions control still represents a challenge for surgeons and oncologists. Nevertheless, according to this and other authors’ recent experiences, ECT could be considered the gold standard strategy for early-stage patients, but at the same time it could be considered as a valid option in controlling Kaposi’s Sarcoma locally advanced lesions.
Novel Lipid Mediator 7S,14R-Docosahexaenoic Acid: Biogenesis and Harnessing Mesenchymal Stem Cells to Ameliorate Diabetic Mellitus and Retinal Pericyte Loss
Authors: Lu Yan , Tian Haibin , Peng Hongying , Bazan Nicolas G. , Hong Song
Published: January 2024

Stem cells can be used to treat diabetic mellitus and complications. ω3-docosahexaenoic acid (DHA) derived lipid mediators are inflammation-resolving and protective. This study found novel DHA-derived 7S,14R-dihydroxy-4Z,8E,10Z,12E,16Z,19Z-docosahexaenoic acid (7S,14R-diHDHA), a maresin-1 stereoisomer biosynthesized by leukocytes and related enzymes. Moreover, 7S,14R-diHDHA can enhance mesenchymal stem cell (MSC) functions in the amelioration of diabetic mellitus and retinal pericyte loss in diabetic db/db mice. MSCs treated with 7S,14R-diHDHA were delivered into db/db mice i.v. every 5 days for 35 days. Blood glucose levels in diabetic mice were lowered by 7S,14R-diHDHA-treated MSCs compared to control and untreated MSC groups, accompanied by improved glucose tolerance and higher blood insulin levels. 7S,14R-diHDHA-treated MSCs increased insulin+ β-cell ratio and decreased glucogan+ α-cell ratio in islets, as well as reduced macrophages in pancreas. 7S,14R-diHDHA induced MSC functions in promoting MIN6 β-cell viability and insulin secretion. 7S,14R-diHDHA induced MSC paracrine functions by increasing the generation of hepatocyte growth factor and vascular endothelial growth factor. Furthermore, 7S,14R-diHDHA enhanced MSC functions to ameliorate diabetes-caused pericyte loss in diabetic retinopathy by increasing their density in retina in db/db mice. Our findings provide a novel strategy for improving therapy for diabetes and diabetic retinopathy using 7S,14R-diHDHA-primed MSCs.
Equine Metacarpophalangeal Joint Partial and Full Thickness Defects Treated with Allogenic Equine Synovial Membrane Mesenchymal Stem/Stromal Cell and Umbilical Cord Mesenchymal Stem/Stromal Cell Conditioned Medium: The Proof-of-Concept
Authors: Reis I.L. , Lopes B. , Sousa P. , Sousa A.C. , Caseiro Ana Rita , Briote I. , Rocha Ana Matilde , Pereira J.P. , Mendonça C.M. , Santos J.M. , Lamas Luís , Atayde L.M. , Alvites R.D. , Maurício Ana Colette
Published: January 2024

Articular cartilage healing and repair is one of the biggest clinical challenges in trauma and orthopaedic medicine, leading to high economic loss due to athletic impairment in sport horses. Multipotent Mesenchymal stem/stromal cells are part of novel therapeutic arsenal aimed at tissue regeneration and restoring organ function. These cells release biomolecules and factors in the culture media, producing the so called conditioned medium, which have a pro-regenerative effect through paracrine mechanisms. Considering this, a therapeutic product combining equine synovial membrane derived Mesenchymal stem/stromal cells and equine umbilical cord stroma-derived Mesenchymal stem/stromal cells conditioned medium was employed. In this work the treatment of two articular defects, in the first phalanx and third metacarpus of the left front limb of a five-year-old horse, is described. Following surgical debridement of the lesions, the treatment comprised two intra-articular administrations of the above-mentioned therapeutic combination, 15 days apart. This was followed by a thorough rehabilitation program. A second-round treatment was performed 6 months later. Diagnostic imaging demonstrated significant improvement of the articular defects. The clinical outcome allowed a full return to the athletic performance demonstrating the safety and potential advantages of this approach when compared with other therapeutic options.
TIM3 or HAVCR2 in Breast Cancer Instead of Suppression May Invoke Immune Action in Tumor Micro Environment
Authors: BASU ANUPAM , GHOSH ARUNITA , Dolui Barnali , Majumdar Banani , Krishna Pallavi , Bandopadhaya Arghya
Published: January 2024

Immune checkpoint receptors play a crucial role in steering tumor progression, prompting a focused investigation into the role of TIM3 in breast cancer. Analysis of TCGA BRCA data unveiled diverse correlations between TIM-3 expression and immune cell infiltration across subtypes. In our in-house cohort studied through IHC, significant changes in TIM3 expression with tumor grades were observed. Higher TIM3 expression correlated with increased disease-free survival in pan breast cancer, marking the first revelation of TIM3's positive role in pan BC prognosis. The study indicates that alluring TIM3 response, rather than suppression, may enhance breast cancer prognosis.