bluuebunny/crossref_metadata_2025 huggingface dataset:
Manifestations of social inequality in connection with the COVID-19 epidemic among men who have sex with men and transgender people in Ukraine: results of a survey of users of the mobile application “Hornet”
Authors:   Eurasion Coalition on Health, Rights, Sexual and Gender Diversity 142, Pärnu maantee, Tallinn, 11317, Estonia, Kasianczuk M. H.
Published: November 2023

Data on the effects of COVID-19-related social restrictions on LGBT people are scarce, and Eastern Europe and Central Asia (EECA), which is characterized by an unstable economy, the presence of interstate conflicts and heterogeneous access of vulnerable groups to social services remain a “white spot” on the research map. The article aims to close knowledge gaps about the socioeconomic effects of the COVID-19 pandemic among men who have sex with men and transgender people in Ukraine. A cross-sectional online survey of 820 Hornet mobile app users who are male, over the age of 18, and reside in Ukraine was undertaken from March to May 2020. The analysis is based on one- and two-dimensional distributions. The chi-square test for categorical variables and comparison of means for the PHQ-4 depression and anxiety scales were used to compare the social vulnerability of various sample groups. COVID-19 significantly impacted the economic circumstances of the people surveyed: 24% lost at least two-thirds of their income, 41% lost their jobs, and 23% found themselves in extreme poverty and had to limit their food intake. Respondents who belong to socially more vulnerable populations were particularly heavily struck by the COVID-19 epidemic’s societal and economic changes in 2020. However, the prevalence of suicidal ideations among respondents did not change compared to the pre-pandemic period. The average data on respondents’ mental health (PHQ-4) scale is 4,9 (95% CI: 4,6–5,3), which did not exceed the bounds of mild deviations from the norm. The limitation of physical freedom, which resulted in economic losses, causing the level of depression and anxiety among suffering groups to be worsened. The findings show the negative effects of COVID-19 restrictions on LGBT physical, social, and mental well-being in Ukraine. The epidemic’s harmful effects harmed the region’s men who have sex with men, but more socially vulnerable categories were hardest hit. Thus, the outbreak made already existing disparities worse.
Prospects for the development of the accumulative pension system of Ukraine under the influence of the shocks of armed aggression
Authors:   Ptoukha Institute for Demography and Social Studies NAS of Ukraine 60, Shevchenko blvd., Kyiv, 01032, Ukraine, Makarenko O. I.
Published: November 2023

The author demonstrates the assessment of the current state of the Ukrainian pension system and the analysis of the possibilities and prospects for launching the secondary (state) and development of the tertiary (non-state) levels of the accumulative component of the pension system of Ukraine under the conditions of the active phase of military aggression by Russia. The urgency of the work is due to the critical state of the pension system in Ukraine, which today not only cannot perform its functions regarding the pension provision of citizens in the medium and long term but is bankrupt. The research is also relevant given the repeated unsuccessful attempts to launch the state accumulative component of the pension system and reform the non-state pension provision system. This necessitates a scientific understanding of the possibilities of building an accumulative resilient element of the pension system in current conditions, which involves a clear understanding of the challenges and threats to the viability of such a system. Thanks to this, timely awareness and construction of such a model of the pension component of the accumulation system is possible, which will minimize political (low-quality state policy in this area) and material losses for the pension system participants. The purpose of the article is to analyze and evaluate the use of institutional tools to build a resilient accumulative component of the pension system of Ukraine. The novelty of the research lies in the identification of institutional mechanisms for building a resilient model for the launch of the second and transformation of the third accumulative levels of the pension system of Ukraine, which will allow for solving a complex of current and strategic issues: from reducing the burden on the Pension Fund of Ukraine in the current conditions to forming the prerequisites for obtaining a decent pension for citizens of our countries in the future. The research methodology in the article is based on the use of information from open sources, assumptions, expert opinions and assessments, the experience of building the accumulative component in different countries, etc. The choice of such a methodology is conditioned by the impact of Russia’s military aggression on all elements of life in our country, particularly the acquisition and formation of operational and reliable statistical information.
A new social policy as a way to restore human capital
Authors:   National Institute for Strategic Studies 7-А, Pyrohova Str., Kyiv, 01054, Ukraine, Koval O. P. , Vlasenko R. V. ,   National Institute for Strategic Studies 7-А, Pyrohova Str., Kyiv, 01054, Ukraine
Published: November 2023

The article outlines the approaches and basic principles of forming a new social policy, which Ukraine should pursue in post-war reconstruction. It was determined that the primary goal of such policy should be a change in the paradigm of interaction between the government and society, which would ensure a transition to more pragmatic and effective relations between these parties, social compensation to alleviate social contradictions, as well as “depreciation” of conflicts. The authors emphasized that social protection should become less aimed at providing benefits and assistance to people experiencing poverty and more emphasis on supporting the self-help of Ukrainians. The focus is not only on delivering consumer goods but also on stimulating initiative and self-sufficiency skills. The article outlines the goals and tasks of the new social policy, which consist of restoring public trust in the state, comprehensive transformation of approaches to wages, taxes and social insurance, promotion of adequate employment, ensuring real efficiency of social expenditures, unification of efforts of society, business, and government. The new social policy’s principles should be determined: humanism and social justice, systematicity and comprehensiveness, preventive measures, targeting, adaptability, and multi-subjectivity. The authors suggested mechanisms for implementing the new social policy, among which a special place is taken by a social dialogue based on a four-way (employees, employers, state, local self-government bodies) and four-level (national, branch, territorial and local) model. Corporate social responsibility is defined as a means of deepening social dialogue and the need for its implementation in the form of a national policy model and its normative consolidation, as well as strengthening the joint efforts of business, the state, and civil society organizations to implement such a model, is emphasized.
Digest of U-Report surveys: third quarter of 2023 (domestic tourism, radiation and nuclear safety, financial literacy)
Authors:   NGO ", Demchuk V. S. ,   Ukrainian Volunteer Service",   46/2, Kniaziv Ostrozkykh Str., Kyiv, 01015, Ukraine
Published: November 2023

Paper demonstrated the results of surveys of the innovative youth project U-Report for July – September 2023: domestic tourism, radiation, and nuclear safety, financial literacy.
High-resolution ultrasound and MRI in the evaluation of pectoralis major injuries
Authors:   Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, USA, Chadwick Nicholson , Weaver Jennifer S. ,   Department of Radiology, University of Texas Health San Antonio, San Antonio, USA, Shultz Christopher ,   Department of Orthopedics and Rehabilitation, University of New Mexico, Albuquerque,USA, Morag Yoav ,   Department of Radiology, University of Michigan, Ann Arbor, USA, Patel Arjun ,   Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, USA, Taljanovic Mihra S. ,   Departments of Medical Imaging and Orthopedic Surgery, Banner University Medical Center, Tucson, Arizona, USA
Published: November 2023

The pectoralis major muscle is the largest muscle of the anterior chest wall. The primary function of the muscle is to adduct and internally rotate the arm at the shoulder. The pectoralis major muscle is broken down into two main components or “heads” based upon muscle fiber origin: clavicular and sternal. Pectoralis major muscle injury results from direct trauma or indirect force overload. The inferior sternal head fibers are the most com- monly torn. The pectoralis major tendon most commonly is torn at the humeral insertion. Magnetic reso- nance imaging and high-resolution ultrasound have value in diagnosing pectoralis major muscle injury and help guide clinical and surgical management. Non-operative versus operative management of pectoralis major tears is dependent upon accurate diagnosis of tear location and severity on imaging. Operative management is recommended for tears at the humeral insertion and for musculotendinous junction tears with severe cos- metic/functional deformity. The indications for surgical intervention have been further expanded to complete intra-tendinous tears, defined as the mid-tendon substance between the myotendinous junction and humeral insertion, and those located at the sternal head/posterior lamina. This paper reviews normal pectoralis major anatomy and the spectrum of injury on magnetic resonance imaging and ultrasound. The importance of re- gional anatomical landmarks in assessing for pectoralis major muscle injury will be described. Other patholo- gies, such as tumor and infection, can also affect the pectoralis major muscle and key imaging features will be discussed to help differentiate these entities. Operative and non-operative management of pectoralis major muscle injury is described with examples of pectoralis major repair on post-operative imaging.
Practical approach to ultrasound of soft tissue tumors and the added value of MRI: how I do it
Authors:   Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Griffith James Francis
Published: November 2023

This review outlines a practical approach to the everyday assessment of both non-neoplastic and neoplastic soft tissue tumors, focusing on ultrasound examination, though emphasizing the added benefit of magnetic resonance imaging in certain instances. Ultrasound approach and assessment, practical scenarios, report- ing, biopsy, and follow-up are covered, as well as the criteria used to distinguish benign from malignant tumors. The potential benefits and current limitations of elastography and contrast-enhanced ultrasound in assessment are also addressed. Examples of commonly encountered soft tissue tumors are shown. Ul- trasound can characterize most soft tissue masses based on their ultrasound appearance alone. Following ultrasound examination, three potential scenarios usually exist in clinical practice: (a) confident regarding diagnosis, (b) indeterminate mass with no evidence of malignancy, and (c) indeterminate mass with pos- sibility of malignancy. A diagnostic pathway for each of these scenarios is provided. Magnetic resonance imaging is generally not helpful in further characterizing masses which are indeterminate on ultrasound assessment, though it is helpful in addressing other issues such as exact tumor location and neurovascular bundle involvement that may not be fully resolved on ultrasound examination. In these situations, mag- netic resonance imaging examination can be tailored to address those specific questions that have not been adequately addressed on ultrasound examination. In this sense, both examinations are highly complemen- tary. Tips for undertaking magnetic resonance imaging examinations are provided.
Increasing the Environmental Friendly of Process Fluids Used for Well Drilling
Authors:   Saint Petersburg Mining University, Lavrentiadi Yuriy , Leusheva Ekaterina ,   Saint Petersburg Mining University
Published: November 2023

An important aspect of hydrocarbon drilling is the use of drilling fluids that remove cuttings and stabilize the wellbore, providing better filtration. The properties of drilling fluids are essential to the success of any drilling operation. Fluids were originally developed to enable and cost effectively rotary drilling in subterranean formations. In addition, drilling fluids were designed to form a filter cake, which was primarily designed to reduce filtrate loss to the formation, was thin, and retained the drilling fluid in the wellbore. One of the most important functions of drilling fluids is to minimize the amount of drilling fluid filtrate entering a hydrocarbon containing formation, which can cause damage to the formation due to changes in rock wettability, fines migration, mud plugging with solids, and formation water incompatibility. To stabilize these properties, a number of additives are used in drilling fluids to ensure satisfactory rheological and filtration properties of the fluid. However, the commonly used additives are hazardous to the environment: when drilling fluids are disposed of after drilling operations, they, together with drill cuttings and additives, are discharged into water bodies and cause unwanted pollution. Therefore, these additives should be replaced with additives that are environmentally friendly and provide superior performance. In this regard, biodegradable additives are needed for future research. The review article presents an investigation into the role of various biowastes as potential additives for use in water-based drilling fluids. The use of waste-derived nanomaterial was considered, and rheological and filtration studies of water-based drilling fluids were carried out to evaluate the effect of waste additives on the performance of drilling fluids.
Directions for Improving the Compositions of Reverse Emulsions for Well Plugging
Authors:   Independent author, Glushchenko Viktor , Khizhnyak Grigoriy ,   Perm National Research Polytechnic University
Published: November 2023

Well killing is the most common technological process in oil production. Inverse emulsions are used as an effective fluid in the combined killing method. At present, some potential possibilities of inverse emulsions have not been analyzed both in terms of improving their compositions and technological methods of practical implementation. The paper considers a number of promising research areas for obtaining, improving the compositions of inverted emulsions and the method of their application with injection into the bottomhole formation zone before filling the wellbore with mineralized water. Natural oils of co-emulsifiers - ethoxylated oil-soluble surfactants, and filtration reducers - technical lignosulfonates, starch, latex were proposed as constituent components of hydrocarbon media. Attention was focused on the need for experimental evaluation of the rate of settling of reverse emulsions along the wellbore in formation water and oil, obtaining and studying stable reverse emulsions using high-density salts of CaBr2, ZnBr2, ZnCl2, polyhydric alcohols.
DSG4 Gene Variants as a Cause of Hypotrichosis in the Child with Severe Atopic Dermatitis: Clinical Case
Authors: Murashkin Nikolay N. , Epishev Roman V. , Dubenko Olesya D. , Materikin Alexander I. , Opryatin Leonid A. , Ivanov Roman A. , Savelova Alena A. , Leonova Maria A.
Published: November 2023

Background. Hypotrichosis is a heritable form of alopecia that causes almost complete scalp hair loss in childhood. The diagnosis is typically established according to medical history and clinical picture. Genetic testing is an additional diagnostic method that allows to establish “hypotrichosis” in cases of ambiguous or subtle clinical signs of the disease, as well as to perform differential diagnosis of this condition with others commonly associated with atopic dermatitis (focal and diffuse alopecia). Clinical diagnosis of hypotrichosis in patients with severe dermatosis is challenging.

Clinical case description. The girl, aged 2 years 4 months, was hospitalized with complaints on extended rash on the body with severe itching, and changes in hair thickness, quality of hair shaft, and hair loss. Severe atopic dermatitis and hypotrichosis were diagnosed. The diagnosis of atopic dermatitis was established clinically (SCORAD — 65), the diagnosis of hypotrichosis (type 6, monilethrix-like hypotrichosis) was confirmed via molecular genetic testing (nucleotide variant c.699C>T in exone 13 of the DSG4 gene (OMIM # 607892)). Patient's mother, brother, and two sisters were diagnosed with the nucleotide variant chr18:31409487C>T in heterozygous state in the DSG4 gene. Mother and brother had no clinical manifestations, while both sisters had mild scalp hair damage, as well as eyebrows and eyelashes, since birth. There were no clinical manifestations of atopic dermatitis in parents and other children in the family.

Conclusion. Hypotrichosis clinical signs can be subtled, smoothed, or imitate the symptoms of other comorbid conditions, especially in patients with comorbidities or severe dermatosis. Also worth noting is that changes in certain genes can aggravate the course of atopic dermatitis. In this clinical case, mutation in the DSG4 gene leads to epidermal barrier failure by disrupting the synthesis of desmosomes transmembrane components. Thus, geneticist consultation and genetic testing (search for changes in certain genes) are crucial in such cases.
TNF-α Inhibitor-Induced Psoriasis and Psoriatic Alopecia in Adolescent with Ulcerative Colitis: Clinical Case
Authors: Ambarchyan Eduard T. , Ivanchikov Vladislav V. , Arakelyan Anna L. , Surkov Andrey N. , Kuzminova Anastasia D. , Bessonov Evgeny E. , Komarova Elena V.
Published: November 2023

Background. Genetically engineered biological therapy has revolutionized the treatment of many chronic inflammatory diseases. It often allows to achieve significant clinical effect and improve the patient's quality of life. However, sometimes it leads to adverse events, and physicians encounter them more often. One of such side effects is paradoxical psoriasis (PP) that can be revealed during the therapy with tumor necrosis factor alpha (TNF-α) inhibitors. PP is the debut or exacerbation of pre-existing psoriasis.

Clinical case description. Patient A., 17 years old, has suffered from ulcerative colitis since 2020; biological therapy with infliximab has been initiated in March 2022. Numerous rashes were revealed, as well as development of confluent alopecia foci on the background of scalp psoriatic damage, during the next hospitalization in December 2022. The patient was examined by dermatologist; diagnosis of PP was established according to the clinical picture and medical history. Skin rashes progressed and ulcerative colitis worsened (diarrheal syndrome, fecal calprotectin levels increased up to 526 μg/g) after cessation of infliximab therapy. Biological therapy with the inhibitor IL-12/23 (ustekinumab) was initiated due to the aggressive cutaneous pathological process and the aggravation of inflammatory bowel disease (IBD) symptoms. The gradual regression of rashes with the restoration of scalp hair growth and ulcerative colitis clinical and laboratory remission were noted during the treatment.

Conclusion. PP is a rare complication that develops during therapy with TNF-α inhibitors, and it is most often observed in patients with IBD. In our case there was aggressive course of psoriasis with severe scalp lesion and hair loss (it is specific type of lesion in such patients). The ustekinumab, inhibitor IL-12/23, treatment efficacy correlates with the literature data on this drug successful use in both nosologies. Ustekinumab can be a first-line therapy in such pediatric patients. This clinical case is the first case in the Russian literature on effective management of PP and ulcerative colitis with ustekinumab in children.
Linear IgA Dermatosis in a Child: Clinical Case
Authors: Murashkin Nikolay N. , Materikin Alexander I. , Epishev Roman V. , Leonova Maria A. , Opryatin Leonid A. , Ivanov Roman A. , Savelova Alena A. , Katunina Oksana R. , Kulikov Kirill A. , Danielyan Daniel R.
Published: November 2023

Background. Linear IgA dermatosis is a rare autoimmune bullous disease characterized by vesiculo-bullous subepidermal lesions (affecting the skin and mucous membranes) and by linear homogeneous IgA deposition in the epidermis basal membrane.

Clinical case description. Clinical case of linear IgA dermatosis in children is presented. Clinical data assessment, histological examination of the skin biopsy (to determine the depth of bullous), immunofluorescent examination (to reveal IgA deposition in the epidermis basal membrane) are crucial for reliable disease diagnosis according to the studies. Altogether it helps to establish the final diagnosis and determine the patient's management. Dapsone is the first-line treatment for this disease, it has proven to be an effective and safe medication.

Conclusion. This case of linear IgA dermatosis is of concern due to disease severity and its rarity in clinical practice. Differential diagnosis is rather complicated and clinically requires high-tech research methods. Only immunofluorescent examination allows to diagnose linear IgA dermatosis accurately. Lesions' regression was achieved due to systemic therapy with dapsone (1.8 mg/kg/day).
Features of Cell-Mediated Immunity in Children with Congenital Ichthyosis and Their Role in the Pathogenetic Management
Authors: Avetisyan Karine O. , Murashkin Nikolay N. , Makarova Svetlana G. , Petrichuk Svetlana S. , Kuptsova Daria G.
Published: November 2023

Background. Congenital ichthyoses (CIs) are a heterogeneous clinical-etiological group of genodermatoses. Typical clinical symptoms of this disease, regardless of the form, are generalized erythroderma, peeling, itching, hyperkeratosis, severe structural and functional disorders of the epidermal barrier, other organs and systems. Patients have an extremely low quality of life due to changes in appearance, discomfort, constant disease symptoms. Thus far, there are no effective treatment methods for ichthyosis. That is why scientific search for new therapies is the topical issue in pediatrics and pediatric dermatology.

Objective. The aim of the study is to examine the cell-mediated immunity state in patients with CI via assessment of the pattern of lymphocyte subpopulations in peripheral blood. The research was conducted to study the content of the main and small lymphocyte subpopulations in 86 patients with established diagnosis of CI aged from 1 month to 18 years. The diagnosis was made according to the clinical data and the results of molecular genetic testing. Comparative analysis of blood immunological indicators in children with CI and in patients with other immunemediated chronic dermatoses: atopic dermatitis (AD; n = 68) and psoriasis vulgaris (n = 55).

Methods. The level of T lymphocytes, T helpers (Th), cytotoxic T lymphocytes (Tc), B lymphocytes, NK cells, Treg-cells (Treg), activated T helpers (Thact), Th17 lymphocytes in peripheral blood was evaluated via flow cytometry using monoclonal antibodies. Statistical analysis was performed via Statistica 10.0. Differences between the groups were assessed via Mann-Whitney non-parametric test, differences were considered significant at p < 0.05.

Results. A significant increase of activated T-helpers level in peripheral blood was revealed in patients with CI and psoriasis compared to children with AD (p < 0.001), as well as an increased levels of B-lymphocytes and Treg in children with CI (p < 0.05).

Conclusion. Children with CI have shown some features of cell-mediated immunity such as: pathological activation of Th lymphocytes, impaired terminal differentiation of naive CD4+ cells to Thact, Treg, Th17 lymphocytes and their proliferation. Comparative analysis of mentioned immunological indicators in children with CI, psoriasis and AD has shown comparable results of increased Thact lymphocytes levels in patients in CI and psoriasis groups. This results open up potential of using immunobiological drugs of psoriasis target therapy within the new management strategy for children with CI.
Funkcja usługodawcza administracji publicznej w świetle konstytucyjnych zasad ustrojowych
Authors:   Uniwersytet Wrocławski, Korczak Jerzy
Published: November 2023

Modern public administration is primarily an administration that provides services to citizens. The key role is played by local government units, to which the Constitution of the Republic of Poland has assigned important public tasks in the sphere of satisfying the collective needs of their residents. The article will analyse constitutional provisions in terms of identifying those systemic principles that serve the implementation of this function of the administration.
Wolność zrzeszania się jako forma realizacji potrzeb społecznych człowieka
Authors:   Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie, Kijańska Klaudia
Published: November 2023

The individual’s use of freedom of association has a significant impact on various aspects of human existence. Its existence determines the opportunity to meet needs and makes it possible to strive to achieve assumed goals together with other people. The interpersonal nature of this type of interaction has consequences. The article aims to demonstrate that the freedom of association affects not only the way in which an individual’s political needs are met, but also the satisfaction of social values and human development. The opportunities that the right to freedom of association brings are derived not only from the organizational forms that individuals can use but also from their individual needs, which this value aims to fulfill.
Miejsce kapitana generalnego w systemie ustrojowym Hiszpanii dawniej i obecnie
Authors:   Kolegium Jagiellońskie – Toruńska Szkoła Wyższa, Dankowski Michał Z.
Published: November 2023

This article is an answer to the question where the rank of the Captain General in the title of the king of Spain came from. Reaching back to the pre-constitutional times, the role of the Captain General in the political system of Spain was defined. Originally he acted as the supreme military commander, with time gaining competences in the field of politics, judiciary and treasury. The essence of the post functions is evidenced by the creation of separate territorial administrative entities – captaincy general. The apogee of the Captain-General’s importance in Spain took place in the 18th century, when with the arrival of Philip V of Anjou at the Iberian Peninsula, the system of Bourbon absolutism began to be implemented in Spain under the Nueva Planta reforms. In the constitutional era, the post was once again reduced to strictly military matters, however traditionally appearing in the royal titulature.
Stany nadzwyczajne w konstytucji Węgier z 2011 r. a praktyka ich stosowania
Authors:   Uniwersytet Śląski w Katowicach, Czyż Anna
Published: November 2023

After Viktor Orbán came to power, a new constitution of Hungary was adopted in 2011, which includes a separate section devoted to the states of emergency. In this time a constitutional state of danger was introduced in Hungary in the face of the covid-19 pandemic in 2020 and the war in Ukraine in 2022, and in the case of the migration crisis in 2015, a state of crisis was introduced regulated by law. The aim of the article is to present the types of states of emergency in Hungary and the practice of their application during the rule of the Fidesz party based on the analysis of legal acts regulating the issue of extraordinary measures. The main thesis assumes that the government of Orbán used the extraordinary situation in the country not only to fight the threat, but also to strengthen its already strong position in the Hungarian political system.
Работа над метроритмом в оперном классе (на примере оперы «Евгений Онегин» П.И. Чайковского)
Authors: Вашерук Илья
Published: November 2023

Пособие раскрывает самый широкий круг вопросов, связанных с проблематикой изучения и применения метроритмических навыков в процессе освоения оперных партий на примерах из оперы П.И. Чайковского «Евгений Онегин». Подобный подход позволяет соединить воедино процесс освоения теоретических и исполнительских дисциплин, способствуя обретению целостности знания об изучаемом предмете.
Английский язык. Учебное пособие для специалистов направления «Транспортный и промышленный дизайн» Часть 1
Authors: Ляхова Елена
Published: November 2023

Учебное пособие по английскому языку предназначено для студентов 2 курса бакалавриата, обучающихся по направлению «Транспортный и промышленный дизайн». Учебное пособие рекомендовано для студентов данного направления подготовки в качестве основной литературы на занятиях по иностранному языку. Тексты для чтения и анализа собраны из аутентичных англоязычных источников для развития умений критического осмысления информации, исследовательской деятельности и сопровождаются профессионально ориентированными заданиями, направленными на развитие созидательных способностей студентов с целью их подготовки к эффективному решению профессионально коммуникативных задач. В пособии предлагаются упражнения, направленные на развитие межкультурной иноязычной профессионально ориентированной коммуникативной компетенции студентов. С этой целью пособие совмещает традиционные пред-текстовые, текстовые и после-текстовые упражнения с элементами геймификации, такими как ролевые и деловые игры, квесты и т.д. Особое внимание уделяется развитию навыков устного общения в профессиональном контексте, для чего в пособии отрабатываются различные стратегии профессионально-ориентированного общения.
Resilient performance faced with a period of economic crisis: Integrated model of conceptions and research strategy
Authors: Rosa Leandro K. , Decourt Roberto F. , Vancin Daniel F.
Published: November 2023

Abstract Purpose: This study seeks to design an integrated model of concepts for research on organizational resilience in a period of economic crisis and synthesize strategy for an empirical approach. Originality/value: By recognizing economic recessions as crisis events, exogenous and recurrent, that challenge the evolutionary trajectory of the business environment and the adaptive capacity of firms, this study focuses on the convergence of scientific fields to unify the business cycle with characteristics and heterogeneous business dynamics from the perspective of resilience. Design/methodology/approach: Initially, we conducted a systematic review of the literature on “business cycle management” and “organizational resilience.” Next, we used various combinations and variations of the terms “economic crisis” and “resilience,” plus “management” and “performance” to expand the base of references from publications in relevant indexes. Thus, through research by authors from different areas of knowledge, the propositions raised here are based on the comprehensive and transversal assimilation of knowledge related to the context of economic crisis and the adaptive dynamics of organizations. Findings: This study organizes and reconciles convergences of scientific fields in an integrated model of concepts for studying organizational resilience throughout business cycles and synthesizes a research strategy with three analysis segments for an empirical approach. Thus, the findings cooperate with several streams of research that focus on the adversities faced by organizations in periods of recession and provide a broad prism of analysis, with significant space to explore the linkage of attributes and actions that favor or hinder the achievement of resilient performance in the face of a period of economic crisis.
DLEU2/EZH2/GFI1 Axis Regulates the Proliferation and Apoptosis of Human Bone Marrow Mesenchymal Stem Cells
Authors: Yao Qing , He Xuezhi , Wang Jing , Liu Juan , Zhang Qing , Zhang Jie , Bo Yawen , Lu Lin
Published: November 2023

Long non-coding RNAs (lncRNAs) has become a vital regulator in the pathogenesis of osteoporosis (OP). This study aimed to investigate the role of lncRNA DLEU2 in the development of proliferation and apoptosis of human bone marrow mesenchymal stem cells (hBMSCs). High-throughput sequencing in bone tissues from 3 pairs of healthy donors and OP patients was used to search for differential lncRNAs. The expression of DLEU2 was also verified in bone tissues. The hBMSCs were transfected with DLEU2 ASO. Cell viability was detected suing MTT. Cell proliferation was determined using colony formation and EdU assays. Cell cycle and apoptosis was detected using flow cytometry. RIP, RNA pulldown, and Co-IP assays were carried out to verify the interaction between protein and protein/RNA. The binding sites between GFI1 and the promoter of DLEU2 was verified using ChIP and luciferase assays. DLEU2 expression was down-regulated in OP patients. Knockdown of DLEU2 expression significantly inhibited proliferation and promoted apoptosis of hBMSCs. Moreover, DLEU2 could interact with EZH2 to induce the activation of GFI1. Additionally, GFI1 transcriptionally activated DLEU2. Taken together, DLEU2/EZH2/GFI1 axis suppressed proliferation and enhanced hBMSC apoptosis. This may provide novel strategy for OP.
Designed by Patricia Urquiola – three spaces for three identities
Authors: Aerts Anastasia , Pombo Fatima
Published: November 2023

In the extensive meaning of interior spaces interrogating architectural quality and the experience of people inhabiting built spaces, it is the aim of this text to contribute to the reflection about interiors’ atmospheric quality. Interiors referring to the sensorial qualities a space sends out have impact in the subjective representation of the space and in the individual use of it. The projects of the contemporary Spanish born designer Patricia Urquiola (°1961) invite to a discussion about design of interiors aiming to conceive spaces with atmospheric quality that express identity. This text addresses from a phenomenological approach three different examples of different typologies and architectural programmes: Casa Moroso, Mandarin Oriental Hotel and Missoni Stores in Milan and Paris. The text concludes that the original achievement of these projects voice the relevance of creating interiors as empathic sceneries of spaces recognized from its identity character and image. It stresses that interior architecture takes a key role in creating places that emphasize architecture as a human experience of atmospheres.
Cytomegalovirus resistance in transplant patients Review
Authors: David Tarragó
Published: November 2023

CMV is a major cause of disease and mortality in patients undergoing Solid Organ Transplants (SOT) and Hematopoietic Stem Cell Transplants (HSCT). In SOT, CMV infection usually establishes itself in the first three months after transplantation in patients who do not receive prophylaxis.
Costly Signaling and China's Strategic Engagement in Arctic Regional Governance
Authors: Wang Yaohui , Ma Yanhong
Published: November 2023

In recent years, China has become an increasingly important actor in Arctic regional governance. While Beijing consistently frames its engagement in the region as a strategy of mutually-beneficial cooperation, some Arctic countries have raised significant concerns about its growing economic presence, warning that China may leverage its geopolitical influence to change the existing norms and rules in the polar region. Facing the mounting “China threat” skepticism, what are Beijing’s coping strategies to belie concerns? Based on a review of the existing research and government documents, particularly Chinese-language scholarly works and official reports, this article specifically identifies two types of costly signaling approaches employed by China to reduce Arctic countries’ distrust. First, China has started to curtail its Arctic investment in oil, gas, and mining while engaging more in sectors that chime well with Western societies’ global environmental values, including clean and renewable energy, ecological research that addresses further climatic change associated with global warming, and other environmentally sustainable industries. Second, Beijing has increasingly involved in regional international organizations, such as the Arctic Council, to signal its willingness to exercise state power under institutional constraints. These approaches aim to send a series of costly signals to conventional Arctic states, reassuring them that China is not a revisionist power that pursues hegemony in the region. Taken together, our findings have both scholarly and policymaking implications to understand China’s participation in Arctic regional governance.
Governing Arctic Seals: A Longitudinal Analysis of News and Policy Discourse
Authors: Gehrke Charlotte
Published: November 2023

Arctic states, regional and local authorities, NGOs, and Indigenous communities have debated how Arctic seals should be governed for more than a century. This governance discourse covers a wide array of issues, from seal hunting and the sale of animal products to the impacts of pollution and climate change. This article examines the frames used by political entities to discuss the regional governance of Arctic seals in the North American Arctic from 1900–2020, a period defined by landmark agreements on seals. Informed by framing and agenda-setting theory, the article employs textual analysis of policy documents and newspaper articles. These serve as a source of information and space for policy advocacy and debate to study political entities’ discourse regarding the issues and policies that shape Arctic seal governance. The analysis focuses on English-language texts from regional and local newspapers and international newspapers of record. The article identifies four dominant frames, namely perceived threats to (a) economic revenue, (b) animal welfare, (c) Indigenous ways of life, and (d) threats emanating from the involvement of NGOs in Arctic regional governance. Each of these frames is associated with one or multiple political entities involved in the regional governance of seals. The article demonstrates how the dominance of these entities and the frames they employ varies over time and corresponds to several anthropogenic threats to seals, including commercial hunting, pollution, and climate change. The article concludes that tensions between local and regional entities and international and non-Arctic entities are reflective of broader Arctic regional governance dynamics.
The Institutional Ingredients of Polycrisis Management: Unpacking European Council’s Handling of the Energy Crisis
Authors: Smeets Sandrino , Beach Derek
Published: November 2023

This article analyses how the European Council and the institutional infrastructure that supports it have been managing the early stages of the energy crisis. This was the time when the European Council, as the “control room” of EU crisis management, was unable to come up with any solutions to high energy prices. It makes a methodological and empirical contribution to the debate on how the European Council system manages (poly)crises. Methodologically, we introduce the method of embedded process tracing to study EU crisis management from within. Embedded process tracing combines mainstream causal process tracing techniques with elements from interpretivist approaches, to deal with context dependency, case heterogeneity, and empirical density. Empirically, we offer a process-management analysis of the first nine months of the energy crisis. We delineate the roles of various actors and institutions: the president of the European Council, the Council Secretariat, the Commission president, and the Commission Services. We unpack the crucial ingredients of polycrisis management: how to get and keep an issue on the agenda, how to shape and steer European-Council-level debates and conclusions, and how to ensure a proper follow-up by the Commission and the Council. Finally, we re-assess the image of the malfunctioning control room and show the causal relevance of the European Council’s early performance.
Digital Rights to the City: Local Practices and Negotiations of Urban Space on Decidim
Authors: Suter Aline , Kaiser Lars , Dušek Martin , Hasler Florin , Tappert Simone
Published: November 2023

The organization, management, and production of urban space through digital information and communication technologies have become a central means for governing urban life. To overcome a lack of citizen-centered practices in today’s smart cities, governments and municipalities institutionalize citizen-centered digital infrastructures such as Decidim, a digital infrastructure proposing non-corporate, decentralized, and collaborative forms of digital production to evoke participatory governance practices and ultimately social transformation (Barandiaran et al., 2018). Swiss city administrations have adapted the Decidim platform for participatory budgeting processes and city-wide participation platforms since 2019. This article explores the process of institutional adoption, focusing on how the use of Decidim impacts local practices and negotiations for governing urban space. The examination of the Decidim platform in the Swiss cities of Zurich and Lucerne will be framed by re-conceptualizing Lefebvre’s right to the city in the age of digital transformation. The findings show that for a successful introduction of the Decidim platform based on principles of the right to the city (a) local needs for a new digital democratic instrument need to be pre-existent, (b) government employees must implement a scope of action which allows organized civil society and grassroots initiatives to appropriate the infrastructure for their own purposes, and (c) local practices of hybrid communication and organizing must be aligned with the structure of the platform. Nevertheless, digital participation tools such as Decidim cannot solve entrenched inequalities such as the financialization of land, the issue of disadvantaged neighborhoods, or the absence of voting rights for certain communities. Therefore, city administrations need to integrate hybrid participation strategies which prioritise collective power over distributive power as well as tackle urban inequalities through political means.
Auditing, Revealing and Promoting Industry in the London Borough of Southwark
Authors: Clossick Jane , Brearley Mark
Published: November 2023

Renewed enthusiasm surrounds the potential for urban industry and its contribution to the socioeconomic diversity of cities, despite concerns about the loss of industrial uses, land, and buildings in high-value, post-industrial cities. Yet, industry is often hidden and undervalued, and methodologies to change the culture around nurturing industry in cities have not been well explored. As a first step in moving this agenda forward, this article proposes effective ways to reveal industrial uses and to advocate for policy protections of the land they occupy. It examines how London Metropolitan University’s School of Art, Architecture and Design (AAD) Cities action researchers applied their Audit, Reveal and Promote methodology to Southwark, a London borough with a high concentration of urban industry. There are key aspects to revealing industrial economies: collecting accurate data on the ground, showcasing local businesses, building stakeholder networks through mutual trust, and creating a space of possibilities between vertical hierarchical and grassroots power networks to enable stakeholders to participate in urban change. This article presents a methodology for cultural change towards valuing a mix of uses, including industry, to transform land development towards retention and densification of industry.
Lambert-Eaton myasthenic syndrome against the background of thyroid cancer: a clinical case
Authors: Khozhenko Elena V. , Kiparisova Elena S. , Larina Iraida V. , Vaulicheva Alexandra L. , Grigoriev Sergey S. , Mavlyudova Elvira S.
Published: November 2023

BACKGROUND: Lambert–Eaton myasthenic syndrome (G73.1 according to ICD-10) is a rare autoimmune disease associated with a presynaptic impairment of neuromuscular transmission due to the production of antibodies to voltage-gated calcium channels. The peculiarity of Lambert–Eaton myasthenic syndrome is manifested in a combination of increased muscle weakness and fatigue with the phenomenon of «working in» — an increase in the muscle strength against the background of muscle load after a short-term maximum contraction. Lambert-Eaton myasthenic syndrome is often associated with small cell lung cancer and very rarely develops with tumors of another localization.
CLINICAL CASE DESCRIPTION: We observed an 80-year-old patient with complaints of weakness and pain in the hips, shoulders, pelvic region, and half-ptosis of the eyelids. For half-ptosis of the eyelids, a differential diagnosis was conducted with myasthenia gravis. Stimulation electromyography revealed the M-response increment, i.e. the phenomenon of “working in”, which is typical for this syndrome. The examination revealed papillary thyroid cancer, which was later treated surgically.
CONCLUSION: This case illustrates Lambert–Eaton’s paraneoplastic myasthenic syndrome, a rare tumor form associated with thyroid cancer.
A clinical case of post-COVID-19 myoendocarditis and arrhythmic syndrome at the outpatient stage
Authors: Pavlyukova Tatiana S. , Klimova Tatiana S. , Esina Elena Yu. , Lagutina Svetlana N. , Skuratova Olga S. , Zuikova Anna A. , Dobrynina Irina S. , Shevtsova Veronika I. , Chizhkov Pavel A.
Published: November 2023

Background: Infection with the SARS-CoV-2 virus entails the development of complications which affect the prognosis of the underlying disease. More than 40% of COVID-19 complications represent diseases of the cardiovascular system, most of which are the rhythm and conduction disturbances. In order to avoid these complications, it is necessary to detect cases of infection in a timely manner at the outpatient stage. Clinical case description: A 40-year-old patient came to the clinic with complaints of interruptions in the heart rhythm that appeared after the coronavirus infection. The laboratory examination (CBC) revealed signs of systemic inflammation (leukocytosis 12.6×109 U/l; erythrocyte sedimentation rate 18 mm/h, C-reactive protein 18 mg/l); the instrumental examination of the heart revealed the rhythm disturbances in the form of frequent ventricular ectopic activity and weakness of the SA node. The patient received propafenone (150 mg, 3 times a day) as a therapy with a positive effect. Against the background of improvement in the patient’s condition and despite the history of myocarditis and a positive result of enzyme immunoassay for antibodies to SARS-CoV-2 (IgG, 10 BAU/ml), the patient was prescribed immunization with the CoviVac vaccine. After the immunization, the condition worsening was observed in the form of an increase in the rhythm disturbances, which required an inpatient treatment. A clinical diagnosis of recurrent ventricular arrhythmia — ventricular extrasystole was established, and the therapy was corrected. The outcome was favorable. Conclusion: Myocarditis is one of the most common complications of SARS-CoV-2 and should be kept in mind at all stages of medical care. This clinical case demonstrates the importance of the correct diagnosis and treatment of post-COVID myocarditis, as well as the need to assess contraindications for SARS-CoV-2 vaccination in patients with cardiac complications.