bluuebunny/crossref_metadata_2025 huggingface dataset:
The Increase in Sagittal Sinus Size in Multiple Sclerosis: Elevated Venous Pressure or Increased Wall Stiffness, a Feasibility Study
Authors: Bateman Grant Alexander , Lechner-Scott Jeannette , Bateman Alexander
Published: April 2022

The cross-sectional area of the superior sagittal sinus (SSS) is larger in multiple sclerosis than normal and correlates with disease severity and progression. The sinus could be enlarged due to a decrease in the pressure difference between the lumen and the subarachnoid space, an increase in wall thickness or increased wall stiffness. The cross-sectional area of the SSS and straight sinus (ST) were measured in 103 patients with multiple sclerosis and compared to 50 controls. The cross-sectional area of the SSS and ST were increased by 20% and 13% compared to the controls (p = 0.005 and 0.02 respectively). The deflection of the wall of the sinus was estimated. The change in pressure gradient, wall thickness or elastic modulus between groups was calculated by modelling the walls as simply supported beams. To account for these findings, the modelling suggests either a 70% reduction in transmural venous pressure or a 3 fold increase in SSS wall stiffness plus an 11% increase in wall thickness. An increase in sinus pressure, although the most straight forward possibility to account for the change in sinus size, may be the least feasible. An increase in sinus wall stiffness and thickness may need further investigation.
Increased expression levels of DLX5 inhibit the development of the nervous system
Authors: Liao# Tingting , Xu# Xia , Wu Junzi , Xie Yi , Yan Jianying
Published: April 2022

Introduction: Preeclampsia (PE) is a hypertensive disorder of pregnancy (HDP). DLX5 plays an important role in the migration and differentiation of subglobus pallidus precursor cells. Material and methods: We established a zebrafish line expressing high levels of DLX5 and investigated changes in behavior and development of the nervous system. Results: The ratios of brain volume area to whole body area at 96 hpf zebrafish in the experimental group (gRNA+CasRx) were significantly lower than the WT group and the negative control group (casRx)(P<0.01). Behavioral trajectory distances and movement speeds exhibited by the 6th day of development in zebrafish in the experimental group (gRNA+CasRx) were significantly shorter (P<0.01) and lower (P<0.05) than the negative control group (gRNA+CasRx), respectively. Conclusions: Data suggested that the increased expression levels of DLX5 can inhibit brain volume development and behavioral activities in zebrafish. Maybe the high expression levels of DLX5 in the pathological state of PE can inhibit the development of the nervous system in offspring.
Induced polyubiquitination of proteins mediated by overexpression of a peptide: a novel tool for targeted protein degradation (TPD) research.
Authors: Nallur Girish
Published: April 2022

A novel strategy for targeting proteins with peptides which give rise to stable ubiquitination has been identified with proteomics. Several bioactive peptides gave rise to characteristic patterns of polyubiquitinated proteins, containing distinct sets of proteins in a cell culture model. Differential mass spectrometry of the ubiquitin-conjugated proteins with one such peptide namely, VB-009, identified proteins predominantly having roles in RNA metabolism, including some that are frequently mutated in diseases, such as, Amyotropic Lateral Sclerosis, Fronto-Temporal Dementia, and myelodysplastic syndrome. The applications of this serendipitous finding for targeting specific targets in TPD are discussed.
Biofuel pellets from spent coffee grounds
Authors: Smirnov Yuri , Sverchkov Ivan , Gabdullina Rushaniya
Published: April 2022

The research is aimed at solving the urgent problem of food industry waste disposal on the example of using spent coffee grounds. The storage of coffee industry waste leads to the loss of potentially valuable raw materials. As one of the most promising solutions, this article considers the use of coffee grounds as the main component for fuel composition with the addition of a binder in the form of crushed cardboard and paper waste. The elemental composition, physical and mechanical properties of fuel pellets and the highest specific heat of coffee biomass and fuel composition based on it were determined in the laboratory studies. It is shown that the waste from coffee production is low in ash and has a high fuel cell content, as well as a high specific heat of combustion. The use of spent coffee grounds as raw materials for biofuel pellets production can be considered as an effective way of processing spent coffee grounds and increasing the value of coffee industry waste.
The synergistic effect of bone marrow mesenchymal stem cells combined with estrogen on repairing rabbit endometrial injury and inhibiting EMT via Wnt/β-catenin pathway
Authors: Yuan Liwei , Cao Jia , Hu Mingyue , Xu Dabao , Li Yan , Zhao Shiyun , Yuan Juanjuan , Zhang Huixing , Huang Yani , Jin He , Chen Meixia , Liu Dan
Published: April 2022

Background
Intrauterine adhesion (IUA) caused by endometrial injury is one of the main causes of female infertility. Bone marrow mesenchymal stem cells (BMSCs) transplantation and estrogen therapy are both promising methods to improve injury. This paper aims to exploring their synergistic effect on repairing rabbit thin endometrium and the possible underlying mechanism of restoring the endometrium morphology.
Methods
The IUA animal model was established by a dual damage method of mechanical curettage and lipopolysaccharide infection. Seventy-five female rabbits were randomly assigned to five groups: sham operation group, IUA model group, BMSCs group, estrogen group and BMSCs plus estrogen group. The number of endometrial glands and the degree of fibrosis were observed by H&E and Masson staining respectively. The expression in markers of fibrosis and EMT were detected using western blotting and immunohistochemistry staining. Additionally, we investigated the distribution and differentiation of PKH26-labeled BMSCs using CK7 as an epithelial marker and Vimentin as a stromal marker by immunofluorescence staining. Finally, western blotting is taken to determine the protein expression of core molecules of Wnt/β-catenin pathway in uterine tissues.
Results
The number of endometrial glands was significantly increased, whereas the area of endometrial fibrosis was decreased in all the treatment groups, with the best effects observed in the BMSCs plus estrogen group. Moreover, downregulated expression of fibrosis markers (fibronectin, CollagenI, a-SMA) and interstitial markers (ZEB1, Vimentin, N-cadherin), as well as upregulated E-cadherin expression were found in the combined group. Further studies showed that the PKH26-labeled BMSCs cells appeared in the endometrial glands and extracellular matrix area when orthotopic transplantation into the uterine cavity. And the abundance of CK7 was increased and Vimentin expression was decreased in the combination treatment group. Additionally, the protein levels of β-catenin, Axin2, C-myc, CycinE of Wnt/β-catenin pathway were higher in the BMSCs combined with estrogen group than in the other treatment groups.
Conclusion
Our study demonstrates that the synergistic effect of BMSCs combined with estrogen therapy in the treatment of injured endometrium is likely to be achieved by inhibiting EMT and activating the Wnt/β-catenin pathway, and represent a promising target for the female infertility.
THE INNOVATIVE COMPONENT OF INDUSTRIAL POLICY: THE EXPERIENCE OF DEVELOPED COUNTRIES AND PERSPECTIVES FOR APPLICATION IN RUSSIA
Authors:   Institute of Economics, Ural branch of the Russian Academy of Sciences, Yekaterinburg, Ivanchenko А.
Published: April 2022

This article is devoted to modern approaches to stimulating innovative development within the framework of industrial policy implemented in the developed countries of the West and Russia in the conditions of scientific, technical and digital transformation of the world economy. It is noted that in Western countries there are different approaches to stimulating the scientific and technical development of industry, the development and introduction of innovations in the production process, differing in the degree of state intervention in the economy, the peculiarities of the problems and tasks solved by each country, a specific set of tools used. At the same time, the overall goal of the policy is similar in different countries: to increase the innovation, dynamism and competitiveness of the national industry. It is also noted that in recent years, the Russian Federation has adopted a number of legislative and regulatory documents aimed at supporting innovations in industry, which use Western experience and, to a large extent, are focused on direct support from the state. Based on the analysis of statistical data and comparison with the indicators of Western countries, an assessment of the effectiveness and efficiency of the measures taken in Russia is given and it is concluded that the measures taken at the moment have not had a significant impact on the acceleration of scientific and technological development and innovative restructuring in the branches of Russian industry. The final part contains a set of proposals on various areas of state policy in the field of stimulating innovative development, including those related to the organization of effective cooperation between scientific organizations and industrial enterprises, cluster development, and macroeconomic measures to support innovation
THE OPPORTUNITIES FOR USING DIGITAL TWINS IN INDUSTRY
Authors:   Institute of Economics of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Korovin G.
Published: April 2022

T he digital twin is one of the most important technological concepts in the framework of Industry 4.0. This term is often used in research and practical works devoted to the prospects of industrial development. The object of this study is the process of digital twin using in industry, and the subject of the study is the economic relations in the process of digital twin use in industry. The purpose of the article is to determine the value of the digital twin in industry, its main characteristics, possibilities of its application and effects for industrial enterprises. The complexity of this object determines the need to use a methodology for collecting fragmented data, systematizing the opinions of scientists and analyzing practical experience. The result of the research is identification of approaches to the definition of the digital twin concept and its complementary concepts. The key features of a digital twin, including a virtual dynamic representation of a physical object, automatic and bidirectional data exchange, the ability to observe, optimize work, simulate behaviour are formulated, and the state of a physical object is predicted in the article. The structure of the digital twin in the form of basic elements and information and management links is presented. The classification of digital twins, related important technological directions is proposed. The analysis of the practice of creating and using a digital double in industry allowed the author to determine the scope of its application and the main effects of use.The results of the study can be useful for researchers, specialists of industrial enterprises, representatives of government authorities to form a strategy for the industrial complex development in the process of digitalization. The obtained results can become the basis for the further development of the digital twin concept using methodology in the domestic industry
Methods for nonparametric statistics in scientific research. Overview. Part 2
Authors: Nikitina M. A. , Chernukha I. M.
Published: April 2022

The use of nonparametric methods in scientific research provides a number of advantages. The most important of these advantagesare versatility and a wide range of such methods. There are no strong assumptions associated with nonparametric tests, whichmeans that there is little chance of assumptions being violated, i. e. the result is reliable and valid. Nonparametric tests are widelyused because they may be applied to experiments for which it is not possible to obtain quantitative indicators (descriptive studies)and to small samples. The second part of the article describes nonparametric goodness-of-fit tests, i. e. Pearson’s test, Kolmogorovtest, as well as tests for homogeneity, i. e. chi-squared test and Kolmogorov-Smirnov test. Chi-squared test is based on a comparisonbetween the empirical (experimental) frequencies of the indicator under study and the theoretical frequencies of the normal distribution. Kolmogorov-Smirnov test is based on the same principle as Pearson’s chi-squared test, but involves comparing the accumulated frequencies of the experimental and theoretical distributions. Pearson’s chi-squared test and Kolmogorov test may also be usedto compare two empirical distributions for the significance of differences between them. Kolmogorov test based on the accumulation of empirical frequencies is more sensitive to differences and captures those subtle nuances that are not available in Pearson’schi-squared test. Typical errors in the application of these tests are analyzed. Examples are given, and step-by-step application ofeach test is described. With nonparametric methods, researcher receives a working tool for statistical analysis of the results.
Targeting multi-loop integrals with neural networks
Authors: Winterhalder Ramon , Magerya Vitaly , Villa Emilio , Jones Stephen , Kerner Matthias , Butter Anja , Heinrich Gudrun , Plehn Tilman
Published: April 2022

Numerical evaluations of Feynman integrals
often proceed via a deformation of the integration contour into the complex plane. While valid contours are easy to construct, the numerical precision for a multi-loop integral can depend critically on the chosen contour. We present methods to optimize this contour using a combination of optimized, global complex shifts and a normalizing flow. They can lead to a significant gain in precision.
Celestial holography: Lectures on asymptotic symmetries
Authors: Aneesh Prema B. , Compère Geoffrey , Pipolo de Gioia Leonardo , Mol Igor , Swidler Bianca
Published: April 2022

The aim of these Lectures is to provide a brief overview of the subject of asymptotic symmetries of gauge and gravity theories in asymptotically flat spacetimes as background material for celestial holography.
Innovative Environment in Public Catering
Authors: Gornikov Nikolaj , Mayurnikova Larisa , Novoselov Sergey , Krapiva Tatyana , Koksharov Arkadiy
Published: April 2022

Public catering is a very specific sphere with a number of factors that hinder innovative development. As a result, local public catering businesses require innovative elements that would be tailored for their needs. The research objective was to analyze the prospects of the public catering industry in the Kemerovo Region and design an instrument for its innovative environment.

The research featured public catering enterprises, food industry universities, consumers, and market, as well as related products, services, and technologies. It also involved such elements of local innovation infrastructure as business incubators, technology transfer centers, core facility centers, and industry-specific innovation clusters. The analysis relied on such basic methods as analysis, generalization, systematization, and synthesis.

State regulation stimulates research and innovative activity by financing projects in priority areas of science and technology. For example, programs UMNIK and START choose applicants with the best innovative project. These programs need new methods of selecting the winners and organizing their cooperation. The research offers a stage-by-stage mechanism of interaction, goal setting, and decision making. The infrastructure elements belonged to the innovation cycle: a student business incubator, an Infopark, a core facility center, a technology transfer center, and a industry-specific cluster. Industry-specific clusters proved effective for the public catering sector.

Innovative activity makes sense when it is integrated with universities and regional infrastructure. Regional food catering infrastructure needs innovative elements and innovative projects, and industry-specific clusters can bring these novelties to the market.
Determining the Residual Amount of Amphenicol Antibiotics in Milk and Dairy Products
Authors: Chaplygina Olga , Prosekov Alexander , Vesnina Anna
Published: April 2022

Controlling the level of amphenicol antibiotics in animal products is an important task for the contemporary food industry. Amphenicols are widely used in agriculture. Residual antibiotic substances enter the human body with food of animal origin, e.g. milk, and may lead to resistance to antimicrobial drugs. The research objective was to analyze scientific publications on various methods for identifying residual amphenicol antibiotics in milk and dairy products. The review covered six years of Russian and foreign publications from the PubMed databases of the National Center for Biotechnology Information (USA), Scopus and ScienceDirect databases of the Elsevier, the Web of Science platform, and the domestic electronic library eLibrary.Ru. Screening and quantification proved to be the main methods for their determination. Chromatographic methods, i.e. various types of high performance liquid chromatography, appeared to be especially effective. These methods often experience problems with sample preparation because milk tends to clog the capillary. Thus, food science needs further studies in the field of milk purification and isolation of amphenicols. The article describes the main methods for identifying amphenicol antibiotics in milk and dairy products and defines the prospect of further research.
Soviet Opposition to British Expansion in Xinjiang Province during the Period of National Movement of Indigenous Peoples in 1931–1934
Authors: Barmin V. A.
Published: April 2022

The article deals with the development of international relations in Central Asia in the 1930s. The research featured the relationship between England and the Soviet Union during the uprising of the indigenous peoples of Xinjiang against the Chinese administration in 1931–1934. The analysis involved recent publications and archival sources. The research clarifies the historical picture of the confrontation between Great Britain and the Soviet Union in Central Asia. London made persistent attempts to establish its control over the rebel movement in order to gain economic and political influence in the province, which it had lost in the 1920s. However, the reciprocal actions of the Soviet government proved effective and completely deprived Britain of any serious prospects in that region. The confrontation, its forms, methods, and results affected the entire complex of international relations in Central Asia. The conflict became the final episode of the Great Game, which later determined the predominant position of the Soviet Union in Central Asia. Contrary to the opinion of many western researchers, the USSR never intended to annex the territory of Xinjiang. The research summarizes the history of international relations in Central Asia.
John Major’s Assessments of Brexit: Prospects for the UK
Authors: Menshchikova Yu. V.
Published: April 2022

The article introduces an alternative opinion on Brexit voiced by John Major, who was the Prime Minister of the United Kingdom when it joined the European Union. In his public speeches, John Major touched upon such issues as national sovereignty, British identity, migration, economy, political and diplomatic influence, state unity, etc. John Major believes that Brexit will eventually do more harm than good and that the pro-Brexit rhetoric is a manifestation of populism. He does not consider the European Union as a threat to the British identity. The research was based on I. S. Semenenko’s idea of the panEuropean identity as a resource for the development of the European Union. Even though Brexit and Covid-19 weakened the European identity, the further development of identity policy is likely to strengthen the sense of belonging. Thus, John Major’s reasonable rhetoric can be considered from the opposite standpoint.
Dynamics of the Stress-Recovery Balance of Figure Skaters in the Context of Individual Psychological Support Programmes
Authors: Tsehmeistruk E. A. , Shalina N. K. , Kozlova N. V. , Levickaya T. E.
Published: April 2022

The article shows the dynamics of the stress-recovery balance of skaters in the context of individual psychological support programs. The study followed figure skaters 14–15 years old: athletes of the experimental group (n=15) underwent individually formed psychological support programs for three weeks, in the control group (n=15) directed psychological support was not implemented. The diagnostic tool is presented by "Stress recovery" questionnaire for athletes (E. Y. Kovbas, 2015). It was revealed that female athletes have difficulties with expectations regarding sports training and success in sports, insufficient use of psychological skills in preparing for a sports load and a decrease in the quality of sleep. hese positions were considered as targets of psychological influence, in accordance with which individual programs of psychological support were developed. Following the implementation of the programmes, a positive trend was observed in the balance of stress and recovery of skaters: the level of general and sporting recovery is increasing. The pilot group showed higher recovery rates and lower stress indicators. According to the results of the implementation of individually formed programs of psychological support, there was a shift in the balance of stress-recovery towards recovery.
Additional Meanings of Human Body-related Idioms: Context, Semantics
Authors: Zakirova A. A. , Andreeva M. I.
Published: April 2022

The paper addresses a vital issue of forming idioms with nominations of human body. Human body-related words nominating body parts, physiological and mental processes are used to form numerous English idioms. In given paper these idioms are referred to as human body-related. The paper aims at revealing the specifics of lexical and semantic constituents of the idioms with reference to their contexts. We collected 200 human body-related English idioms from academic books and dictionaries. The research comprised four stages. The thematic classification based on the lexical structure of the idioms revealed prevalence of the idioms comprising words head, eyes, heart, back, foot, and hand. The similarities found in the meanings of all the idioms under study provided semantic classification into five groups, namely, characteristics, action, state, causation, and ability. Next we focused on contextual and semantic specifics of the idioms. In particular, the idioms, containing the word head were studied in the texts of the British National Corpus. The contexts provided the following additional meanings of the idioms: higher position, achievements, location, expenses, and inability to do something. The revealed collocations follow AV+K type. The obtained results and developed algorithm may be applied to lexical and contextual studies of idioms and lexical groups.
The EU Agenda on Migration and Development towards ACP countries: Challenges of the Pandemic
Authors: Pogorelskaya A. M.
Published: April 2022

The article covers 30 years of EU agenda on migration and development. The research objective was to assess its continuity, determine the main trends, and outline the challenges that the cooperation between the EU and the ACP has to face after the pandemic. The EU agenda on migration and development proved to be rather stable. However, the EU motivates migration cooperation by development aid while most ACP countries do not welcome this approach. As a result, the contradictions between the EU and the ACP still exist, despite their formal cooperation after the Cotonou agreement expired. The main trends in the EU policy were the principle of conditionality and the EU's attempts to abandon the universal approach to their ACP partners. The COVID-19 pandemic has aggravated the contradictions in migration and development issues, thus preventing the European Union from upgrading its development policy. The pandemic has the following consequences: global increase in securitization of immigration; strict entry rules and immigration policies; the prospect of expanding access to health care systems for citizens and immigrants. These consequences will inevitably affect the relations between the EU and the ACP.
European Union Policy in the South Caucasus after the Karabakh War of 2020
Authors: Yumatov K. V.
Published: April 2022

The article focuses on the transformation of the European Union’s policy in the South Caucasus after the NagornoKarabakh war of 2020. Before the war, the foreign and security policy in the region had depended on the OSCE Minsk Group, Georgia’s role in the Russian-Georgian confrontation, and the Eastern Partnership program for the South Caucasus. After Azerbaijan won the Nagorno-Karabakh war with Turkey’s support, the previous line of policy stopped being effective. It failed to unite the countries of the South Caucasus, to remove the Russian Federation from the region, and to make the European Union a real mediator in the conflict zone. The democratization of the local political regimes also failed, despite the proEuropean position of Georgia and the velvet revolution in Armenia. As a result of the Armenian-Azerbaijani war of 2020, Russian and Turkish troops entered the South Caucasus, and Russia, Turkey, and Iran started acting as peace mediators. The European Union failed to strengthen the role of the OSCE Minsk Group and the mechanisms of the Eastern Partnership in the region. Ever since 2020, it has been trying to develop a common policy for all ethnic and inter-confessional conflicts in the postSoviet space. The European Union keeps failing in its competition and partnership with Russia, while Turkey is getting more active and independent in the region. Thus, the European Union will have to develop a new model of influence in the South Caucasus and the whole post-Soviet space. In the current global confrontation, it is very important to find an international actor able and willing to interact with all parties. The European Union seems to be the one, and its actions in resolving regional conflicts require a detailed research.
Mythology of Myth as the Foundation of Postmodern Culture
Authors: Kuznetsov I. V.
Published: April 2022

The article questions the appropriateness of using the concept of myth in relation to the XX century culture. The term originated in the German Romantic philosophy and philology. The current use of the concept of myth is mostly connected with the irrational side of reality. The concept of neo-mythologism can be applied to the epoch of Modernism because it preserved a substantial understanding of the myth. Post Modernism, however, understood the myth in a formal way, as an expressive means. This understanding was adopted by semiology and structural anthropology. In the contemporary society, the so-called quasi-myths have become an effective tool of controlling mass consciousness. Unsubstantial quasimyths tend to merge into a simulacrum of the mythology of myth. The article describes this simulacrum and reveals that neo-mythologism as a substance-oriented mentality is not peculiar to Post Modernism. Philologically speaking, today’s myth concerns the key issue of historical poetics, i.e. the relationship between tradition and creativity, where individual creativity is a statement of tradition and national myth. This article was originally published in English as a monograph chapter: Kuznetsov I. V. Mythology of Myth in Twentieth-Century Culture. Philological sciences: Modern scholarly discussions. LvivToruń: Liha-Pres, 2019. P. 64–78.
The Wagnerian Layer in I. Annensky’s Poetry
Authors: Nalegach N. V.
Published: April 2022

Passion for R. Wagner’s music and aesthetic ideas was characteristic of the Art Nouveau culture. At the turn of the XIX–XX centuries, it affected the Symbolist theater and shaped the aesthetic and artistic worlds of many Russian authors. Innokentii Annensky stood apart from the Russian mainstream symbolism. In his letter to E. M. Mukhina, he defined himself as a Wagnerian. The role of Wagner's aesthetics in the symbolist drama has received a lot of scientific attention, whereas its effect on the Russian modernist poetry remains largely understudied. This article introduces the Wagnerian layer in I. Annensky’s poetry. His Quiet Songs and The Cypress Chest appeared to have numerous references to such Wagner’s works as The Ring of the Nibelung, Parsifal, Tristan and Isolde, and Faust. The author analyzed I. Annensky’s poetry and correspondence. The analysis showed that the method of leitmotif composition helped the poet to structure his poetic ensembles. I. Annensky adopted Wagner's experience of combining operas into a tetralogy and used it to unite his own poetry into cycles. This device is especially obvious in the themes of secret love, the God sense, and the search for the ideal in his stand-alone cycles and poetry books.
The Moral and Religious Conflict in N. M. Karamzin's Poor Lisa
Authors: Poselenova E. Yu.
Published: April 2022

M. Karamzin’s Poor Lisa is a precedent in Russian literature: it both celebrated and brought down the principles of Sentimentalism. However, many aspects of this canonical text still remain understudied. The present research featured the moral and religious issues in N. M. Karamzin’s Poor Lisa. It also involved some fragments from N. M. Karamzin’s The History of the Russian State; Natalya, the Boyar’s Daughter, and Filalet to Melodor. The methods included the historical and literary approach, as well as comparative and typological analyses. As for N. M. Karamzin’s religious views, the authors agree with those literary critics and historians who relied on N. M. Karamzin’s biography and statements and declared him an orthodox Christian. The research concentrated on various moral and religious components of the story. Lisa’s worldview was shaped by that of her parents, who built their family relations based on the Old Russian Household Book. Lisa’s traditional Orthodox background explains many of her decisions, which critics tend to interpret through the prism of Sentimentalism. Spatial images of the novel seem to correlate with ceremonial tradition: they show how Lisa’s Christian worldview was gradually overtaken by the pagan belief system. The central motif of Lisa’s purity and innocence correlates with those of oblivion, delusion, the death of soul, punishment, built, sin, etc. As a result, the novel can be treated as a dialogue of two world outlook systems: Sentimental ethics vs. religious and moral ideas. The reader sees Lisa from the point of view of a compassionate narrator with a Sentimental worldview. However, a more complex problem of religious ethics appears as a moral background.
Attitude to Personal Security during Identity Formation in University Students
Authors: Ivanov M. S.
Published: April 2022

The research featured the relationship between the indicators of identity and the characteristics of the attitude to personal security in university students. The study relied on M. Kuhn and T. McPartland’s Who am I questionnaire, M. Berzonski’s Questionnaire of Identity Styles adapted by E. P. Belinskaya et al., J. Chik and L. Tropp’s Aspects of Identity, A. A. Ozerina’s Professional Identity, and E. L. Soldatova’s Ego-Identity SEI-test. The attitude to personal safety was investigated by the methods developed by the author. The study involved 238 students of 1–5 year that were majoring in humanities. The cluster and regression analyses of the data obtained by the cross-sectional method identified the related characteristics of identity and attitudes to personal security, as well as their differences at different stages of training. The author revealed some general tendencies in the phenomena that occurred in students during the period of university study. Positive dynamics included the following trends. The professional position became more active (I as a subject of relations). The assessments of threat of losing one’s reputation and connections decreased. Senior students preferred a personal security strategy, i.e. they relied on themselves. Positive dynamics included the following trends. Superficial identity increased, while the autonomy in the awareness of one's own values and emotional component decreased. The assessment of psychological risks and that of criminal organizations increased, while common preventive efforts mostly decreased. Security strategies in terms of the macro environment also changed: senior students preferred adapting strategy (living in an authoritarian society) to individualizing (living in a humane and tolerant society). The article introduces some conclusions about the correlation of identity and attitude to personal security, as well as the complexity and multidirectional nature of their development in university students.
Socialization of Students and Teachers in the Digital Educational Environment in the Context of the Theory of Generations
Authors: Romanova E. A. , Brel E. Yu.
Published: April 2022

Educational institutions need more effective patterns of interaction between teachers and students in digital environment. Digital teaching technologies are associated with the process of socialization. The research objective was to determine the specifics of the socialization of students, teachers, and university staff in a digital educational environment. The analysis relied on the theory of generations developed by W. Strauss and N. Howe. The authors identified the specificity of socialization in generation Z as the perception and accumulation of new information through the prism of digital component of culture. This specificity is essential in teaching and upbringing children and adolescents of generation Z, since they endow digital space and digital information with values and meanings. Differences in the perception of modern technologies caused the so-called digital gap phenomenon. The authors defined two fundamentally important directions in the study of the socialization of generation Z students by the teaching staff of other generations in the context of digital education. The first is to create conditions and activate the process of socialization in the digital educational environment of the older generation teachers. The second is to reduce the digital gap by organizing targeted active communication in the digital educational environment when solving pedagogical problems.
Academic Mobility as an Instrument of International Communicative Cooperation
Authors: Kvasova Yuliya , Leonteva Veronika , Pul'kina Viktoriya
Published: April 2022

The present research featured the effect of academic mobility on international communicative interaction. The objective was to identify the role of international academic mobility in the PR activities of universities. The study relied on the method of content analysis of domestic and foreign scientific publications. The authors used the method of problem interviews to develop an online questionnaire for students involved in international student exchange programs. The authors described the term of PR-technology, as well as the most popular PR activities and types of international academic mobility in higher education institutions. Academic mobility proved to be one of the most effective PR-technologies of higher education institutions. The article introduces a classification of international academic mobility as a process that provides international communicative interaction. International academic mobility proved to have a significant impact on the image of universities and their students in the international arena, as well as on the status of the country in geopolitical, economic, and civil areas.
What is the justifiable demos of a referendum on state secession?
Authors: Reinikainen Jouni
Published: April 2022

The predominant practice for enfranchisement in referendums on state secession only grants avote to residents of the secessionist unit, while referendums on urban secession are oftenall-inclusive, in the sense of enfranchising all residents of the municipality challenged bysecessionism. This paper examines the justifiability of a more exclusive practice at the state levelfrom two principles for delimiting the demos, namely the all-affected principle and theall-subjected principle. The argument of the paper is that both these principles typically sanctionan all-inclusive demos at both these levels of government. However, such a demos would carry aconsiderable risk of majority domination of a separatist minority at the state level, a risk that ismuch lower at the municipal level. The paper claims this to be a conclusive argument againstapplying these principles on referendums on state secession and thus for retaining our currentenfranchisement practices.
Covid-19 vaccine dosages and government factors role on the global variation in covid-19 mortality: A statistical and regression analysis
Authors:   Department of Computer Science, Faculty of Computing and Information Technology Rabigh (FCITR), King Abdulaziz University, Jeddah, Saudi Arabia, et al. Syed
Published: April 2022

The objective of our study was to explore the influence of the current vaccination program and other relevant government factors to explain the variation in Covid-19 mortality in the world. The study involves a cross-sectional survey of Covid-19 related and government factors from 161 countries. We retrieved and processed publically available coronavirus pandemic data (July 17, 2021) from several online databases, excluding countries' data violating correlation and regression analysis assumptions. In addition, partial correlations studies and multivariate analysis were performed to explore the influence current vaccination program and other relevant government factors on the relationship between the explanatory variable and the total deaths due to Covid-19. The partial-correlation studies revealed that controlling for a complete dosage of Covid-19 vaccine per 100 people in the population had a significant (P<0.001) impact on the strength of the relationship between some explanatory variables and the response variable (total Covid-19 mortality). Furthermore, the Stepwise Linear Regression (SLR) model shows that the covariates, namely total_cases, hospital patients per million, hospital beds per thousand, male smokers, and people fully vaccinated per hundred, added significantly (P<0.001) to the prediction of the response variable. Our SLR model validation study revealed that the observed total Covid-19 mortality was highly correlated with the predicted total Covid-19 mortality in various countries (r = 0.977, P<0.001). Our Stepwise Linear Regression model performs significantly better with an R-squared value of 0.958 and adjusted R-squared value of 0.956 than other related regression models built to predict COVID-19 mortality. Based on our current findings, we conclude that governments with better hospital infrastructure and people with complete dosages of the Covid-19 vaccine will have minimal Covid-19 fatalities.
Atendimento online
Authors: Oliveira Mauro Fernandes
Published: April 2022

Diante do advento da pandemia da covid-19 e das transformações que tal circunstância outorgou ao encontro analítico, este artigo buscou revisitar e questionar o que se mostra fundamental ao fazer psicológico em tempos de tantos distanciamentos, enquadramentos e contaminações, guiado pela pergunta: onde vai parar parte da opus analítica quando o corpo sai de cena? Pretendeu ainda instigar um olhar através dos símbolos do nosso tempo, perpassando cinco tópicos: cabeça, tronco, pernas, casa e pulmão, que visam devolver corpo ao fazer dos analistas e da própria psicologia profunda contemporânea. Os argumentos trazidos transcendem em muito as circunstâncias repentinas oriundas da adequação dos consultórios de psicologia para a modalidade de atendimento remoto.
Authors’ Response to Peer Reviews of “Left Ventricular Outflow Tract Obstruction in Patients Treated With Milrinone for Cerebral Vasospasm: Case Report and Literature Review” (Preprint)
Authors: Baulier Charles , Lessert Marc , Chauvet Jean-Louis , Garel Pauline , Bergis Alexandre , Burdeau Julie , Clavier Thomas
Published: April 2022

UNSTRUCTURED

This is the author's responses to peer review reports related to MS# 31019
Evaluating Mobile Apps Targeting Older Adults: Descriptive Study (Preprint)
Authors: Sweeney Megan , Barton William , Nebeker Camille
Published: April 2022

BACKGROUND

Smartphone use has increased dramatically and, in parallel, a market for mobile apps, including health apps, has emerged. The business model of targeted mobile app advertisements allows for the collection of personal and potentially sensitive information, often without user knowledge. Older adults comprise a rapidly growing demographic that is potentially vulnerable to exploitation by those accessing data collected via these apps.

OBJECTIVE

This research examined apps that claimed to be useful to older adults with a goal of (1) classifying the functionality of each app, (2) identifying whether a privacy policy existed and was accessible, and (3) evaluating evidence that could support claims of value to older adults.

METHODS

An environmental scan was conducted using the Google search engine and typing “apps for older adults.” The first 25 sites that this search returned comprised the primary data for this study. Data were organized by descriptive features of purpose (eg, health, finance, and utility), the existence of an electronically accessible privacy policy, price, and evidence supporting each recommended mobile app.

RESULTS

A total of 133 mobile apps were identified and promoted as being the best “apps for older adults.” Of these 133 mobile apps, 83% (n=110) included a privacy policy. Fewer apps designated in the “medical” category included a privacy policy than those classified otherwise.

CONCLUSIONS

The results suggest that most mobile apps targeting older adults include a privacy policy. Research is needed to determine whether these privacy policies are readable, succinct, and incorporate accessible data use and sharing practices to mitigate potential risks, particularly when collecting potentially sensitive health information.
Effectiveness of virtual psychosocial programme on psychological well being and self satisfaction: Quasi – Experimental design (Preprint)
Authors: Sharma Manju , Dhaliwal Dr. Kirandeep , Kumar Dr. Yogesh
Published: April 2022

BACKGROUND

Mental health is critical at every phase of life, from childhood and adolescence through adulthood. So it is very important to balance the mental harmony at these growing phases of life.

OBJECTIVE

To explore whether improvement in psychological well being and self satisfaction occur after implementation of virtual psychosocial programme.

METHODS

The study was Randomized, Quantitative Research Approach, and Quasi – Experimental (Non Equivalent control group pretest- posttest) Design. The experimental group participants were provided intervention for 21 days for an average of 45minutes/day. Postintervention asssessment was done (1day), follow up(15 days). Eligibility criteria included students who were undergraduates and studying in selected nursing institutes (1), willing to participate (2), having their own personal smart phones (3), Having lower and moderate level of psychological well being and moderately satisfied and unsatisfied level of self satisfaction; after screening from RYFF tool for psychological well being and self satisfaction measurement scale for self satisfaction (4). Discriptive and inferential test were used for analysis and P value <.05 was considered statistically significant.

RESULTS

A total of 112 participants were included in the analysis. The finding showed that majority 39(72.2%) were females, 31(57.4%) participants were not involved in any relaxation and other practices like (yoga, meditation, exercise, gym). Intervention in term of psychological well being and self satisfaction (P .00) were found to be statistically significant when assessed on the postintervention day 1 and the same result followed till 15 days of postintervention. A low positive correlation was found (r=.33, P=.01) between psychological well being and self satisfaction of undergraduate nursing students in experimental group (r=.33, P=.01) while in control group it was moderate correlation (r=.48, P=.00) at .05 level of significance. The majority 46(85.2%) of the participants were satisfied after performing intervention.

CONCLUSIONS

Virtual Psychosocial Programme is an effective modality to enhance the psychological well being and self satisfaction among undergraduate students. The findings of the study can be applied while designing future studies or mental health resources in university programs.

CLINICALTRIAL

.
Adverse Mentions, Negative Sentiment, and Emotions in COVID-19 Vaccine Tweets and Their Association with Vaccination Uptake: Global Comparison of 192 Countries (Preprint)
Authors: Jun Jungmi , Zain Ali , Chen Yingying , Kim Sei-Hill
Published: April 2022

BACKGROUND

Many countries show low COVID-19 vaccination rates despite high levels of readiness and delivery of vaccines. The public’s misperceptions, hesitancy, and negative emotions towards vaccines are psychological factors discouraging vaccination. At the individual level, studies have revealed negative perceptual/behavioral outcomes of COVID-19 information exposure via social media where misinformation and vaccine fear flood.

OBJECTIVE

This study extends research context to the global level and investigates social media discourse on COVID-19 vaccine and its association with vaccination rates of 192 countries in the world.

METHODS

COVID-19 vaccine tweets were compared by country in terms of (1) the number per million Twitter users, (2) mentions of adverse events - death, side effect, blood clots, (3) negative sentiment (vs. positive), and (4) fear, sadness, or anger emotions (vs. joy). Artificial intelligence (AI) was adopted to classify sentiment and emotions. Such tweets and covariates (COVID-19 morbidity and mortality rates, GDP, population size and density, literacy rate, democracy index, institutional quality, human development index) were tested as predictors of vaccination rates in countries.

RESULTS

Over 21.3 million COVID-19 vaccine tweets posted between November 2020 and August 2021 worldwide were included in our analysis. The global average of tweets mentioning adverse events was 2% for ‘death’, 1.15% for ‘side effects’, and 0.80% for ‘blood clots.’ Negative sentiment appeared 1.90 times more frequently than positive ones. Fear, anger, or sadness appeared 0.70 times less frequently than joy. The ‘side effect’ mention and fear/sadness/anger emotions appeared as significant predictors of vaccination rates with human development index.

CONCLUSIONS

Our findings indicate global efforts to combat misinformation, decrease negative emotions, and promote positive languages surrounding COVID-19 vaccination on social media may help increase global vaccination uptakes.
Correction: Comparing Online and On-Site Cognitive Behavior Therapy in Major Depressive Disorder: Protocol for a Noninferiority Randomized Controlled Trial (Preprint)
Authors: Ritvo Paul , Gratzer David , Knyahnytska Yuliya , Ortiz Abigail , Walters Clarice , Katz Joel , Laposa Judith , Baldissera Christopher , Wayne Noah , Pfefer-Litman Donna , Tomlinson George , Daskalakis Zafiris
Published: April 2022

UNSTRUCTURED

This is a corrigendum.