bluuebunny/crossref_metadata_2025 huggingface dataset:
Prognostic value of CT radiomics in evaluating lymphovascular invasion in rectal cancer: Diagnostic performance based on different volumes of interest
Authors: Ge Yu-Xi , Xu Wen-Bo , Wang Zi , Zhang Jun-Qin , Zhou Xin-Yi , Duan Shao-Feng , Hu Shu-Dong , Fei Bo-Jian
Published: May 2021

OBJECTIVES:

This study aims to evaluate diagnostic performance of radiomic analysis using computed tomography (CT) to identify lymphovascular invasion (LVI) in patients diagnosed with rectal cancer and assess diagnostic performance of different lesion segmentations.

METHODS:

The study is applied to 169 pre-treatment CT images and the clinical features of patients with rectal cancer. Radiomic features are extracted from two different volumes of interest (VOIs) namely, gross tumor volume and peri-tumor tissue volume. The maximum relevance and the minimum redundancy, and the least absolute shrinkage selection operator based logistic regression analyses are performed to select the optimal feature subset on the training cohort. Then, Rad and Rad-clinical combined models for LVI prediction are built and compared. Finally, the models are externally validated.

RESULTS:

Eighty-three patients had positive LVI on pathology, while 86 had negative LVI. An optimal multi-mode radiology nomogram for LVI estimation is established. The area under the receiver operating characteristic curves of the Rad and Rad-clinical combined model in the peri-tumor VOI group are significantly higher than those in the tumor VOI group (Rad: peri-tumor vs. tumor: 0.85 vs. 0.68; Rad-clinical: peri-tumor vs. tumor: 0.90 vs 0.82) in the validation cohort. Decision curve analysis shows that the peri-tumor-based Rad-clinical combined model has the best performance in identifying LVI than other models.

CONCLUSIONS:

CT radiomics model based on peri-tumor volumes improves prediction performance of LVI in rectal cancer compared with the model based on tumor volumes.
Automatic segmentation of medical images using a novel Harris Hawk optimization method and an active contour model
Authors: Tamoor Maria , Younas Irfan
Published: May 2021

Medical image segmentation is a key step to assist diagnosis of several diseases, and accuracy of a segmentation method is important for further treatments of different diseases. Different medical imaging modalities have different challenges such as intensity inhomogeneity, noise, low contrast, and ill-defined boundaries, which make automated segmentation a difficult task. To handle these issues, we propose a new fully automated method for medical image segmentation, which utilizes the advantages of thresholding and an active contour model. In this study, a Harris Hawks optimizer is applied to determine the optimal thresholding value, which is used to obtain the initial contour for segmentation. The obtained contour is further refined by using a spatially varying Gaussian kernel in the active contour model. The proposed method is then validated using a standard skin dataset (ISBI 2016), which consists of variable-sized lesions and different challenging artifacts, and a standard cardiac magnetic resonance dataset (ACDC, MICCAI 2017) with a wide spectrum of normal hearts, congenital heart diseases, and cardiac dysfunction. Experimental results show that the proposed method can effectively segment the region of interest and produce superior segmentation results for skin (overall Dice Score 0.90) and cardiac dataset (overall Dice Score 0.93), as compared to other state-of-the-art algorithms.
Glandula Tiroid Problem: Literature Review
Authors: Abdul Hafiz Muhammad Zaki , Daan khambri
Published: May 2021

Thyroid cancer is the most common endocrine system neoplasm.Based on the "Pathologycal Based Registration" in Indonesia, thyroidcancer is a cancer with the highest incidence in the ninth rank.According to statistics from the National Cancer Institute (NCI), theincidence of thyroid cancer in men is about 2.5 per 100.000population and women around 6.7 per 100.000 population. Thyroidcancer can affect all age groups and the frequency increases afterthe age of 50 years. Only about 5% can affect the age of 15-20 years.NCI also states that this thyroid cancer can affect 16.000 people peryear. Diagnosis is important to improve the quality of life forsufferers. Clinical diagnosis is the basis for determining furthermanagement, so that knowledge and skills are needed indetermining the diagnosis. The first treatment for a cancer is thebest chance for the patient to achieve optimal cure rates, as is thecase for thyroid cancer.
Giant Lipoma of The Breast: Special Clinical Finding
Authors: Abdul Hafiz Muhammad Zaki , Daan khambri  , Anandia Putriyuni
Published: May 2021

Lipomas are the most common benign tumors of mesenchymal origin.Lipoma of breast is somewhat difficult to diagnose clinically because of fattyconsistency of breast. Giant lipoma is the mass of lipoma that exceeds atleast 10 cm in one dimension or weighs a minimum of 1000 gr.Only veryfew case reports giant lipoma of the breast available in literature becauserarity in size and location. Due to the fatty composition of the breast,difficulties in diagnosis, threatment, and reconstruction are oftenencountered.Presently, we have reported a case of this rare entity in 49years old female with giant tumor of the left breast that most of its mass,causing breast asymmetry and feel heavy. The operative finding: looks likelipoma between pectoralis major muscle and pectoralis minor muscle witha diameter of 31 cm and weighs 3.1 kg. After excision the tumor we need tomammoplasty.Pathology anatomy examination showed a lipoma.
Effectivity of Jatropha multifida L. Leaves Extract as Antibacterial on Streptococcus mutans using In Vitro Testing Methods
Authors: Kinasih Listyaning Kartiko , Idamawati Nababan  , Suci Erawati  , Rouli Natasia M Simanjuntak
Published: May 2021

Intoduction: Health is the condition of the entire body and body parts of an individual who is free from disease both physically, mentally and socially, thus enabling the individual to be able to carry out daily activities more productively. However, many people neglect their own health, especially in the field of dental and oral health. Caries is one of the most common oral and dental problems. The prevalence of dental caries in Indonesia is high, namely 88.8%. Dental caries is caused by Streptococcus mutans bacteria which plays a role in the conversion of sucrose to lactic acid. Infection due to Streptococcus mutans bacteria can be treated by taking antibiotics. Apart from drugs, antibiotics can also be obtained from natural ingredients, one of which is the tintir castor plant (Jatropha multifida Linn) or commonly known as the betadine. Objective: To see the effect of the antibacterial content of tintir leaves against Streptococcus mutans bacteria and to determine the differences in the antibacterial effect of betadine leaf extract (Jatropha multifida L.) from a concentration of 25%, 50%, 75%, and 100% against Streptococcus mutans. Methods: The type of research used in this study was a laboratory experimental study with a post-test-only control group design as the research design and to test the sensitivity of bacteria using the paper disc diffusion test. Data analysis using One-Way ANOVA. Result: The results of this study indicate the effect of tintir castor leaf extract (Jatropha multifida L.) in inhibiting the growth of Streptococcus mutans bacteria.
The Hepatoprotective Effects of Basil Leaf (Ocimum sanctum L.) Extract on Paracetamol Induced Liver Damage in Male Rat
Authors: Panggabean Ronaldo , Nofita  , Ade Maria Ulfa
Published: May 2021

Basil leaf have antioxidants such as flavonoids, so it is thought to have a hepatoprotective effect. This study aims to investigate the effect of basil leaf extract on SGOT and SGPT levels in male rats induced by paracetamol. Basil leaf extract was carried out by the percolation method using ethyl acetate solvent, Some 20 male sprague dawley rats were randomly divided into 5 groups. Basil leaf extract (400 mg/kgBB and 600 mg/kgBB) and sylimarin (100 mg/kgBB) were carried out every day for 28 days, paracetamol was induced 24 hours after giving the last day of basil leaf extract. The parameters measured were SGOT and SGPT level to assess the effect of basil leaf extract on liver damage caused by paracetamol. The results showed that basil leaf extract (400 mg/kgBB dan 600 mg/kgBB) showed that the activities of SGOT and SGPT levels were statistically significant (p<0,05) to negative control. Basil leaf extract shows the effect of hepatoprotector on liver induced by paracetamol, however the effect given was not able to equate with positive control.
Antiviral Therapy in Corona Virus Disease-19 (Covid-19)
Authors: Azka Laisa , Irvan Medison  , Dessy Mizarti
Published: May 2021

Coronavirus disease 2019 (COVID-19) is a disease caused by a new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, previously known as 2019-nCoV), which was first identified in Wuhan City, Hubei Province, PRC. The total number of COVID-19 cases worldwide has reached 102 million cases with 54 million cases recovered and 2.3 million cases dead. Handling for this pandemic is still being carried out. In Indonesia, the antiviral drugs used are those that meet the Emergency Use Authorization (EUA) requirements, and are included in the COVID-19 management guidelines issued by the Ministry of Health. Antiviral options used are Oseltamivir, Favifirapir, Remdesivir. Until now, the use of antivirus is still being researched regarding the effectiveness and security of the antivirus used. Oseltamivir is used as an antiviral for COVID-19 with a mild clinical course, Favifirapir is used for mild to moderate clinical cases of COVID-19. For the use of remdesivir in COVID-19 patients with severe and critis clinical conditions.
ТЕОРЕТИЧНІ ОСНОВИ ТА КЛАСИФІКАЦІЯ РИЗИКІВ З ВРАХУВАННЯМ ОСОБЛИВОСТЕЙ ФУНКЦІОНУВАННЯ ПІДПРИЄМСТВ АГРАРНОГО СЕКТОРУ
Authors: Кириченко Наталя , Алєщенко Людмила
Published: May 2021

У статті досліджено складові ризику в аграрному секторі економіки України, проведено аналіз параметрів бізнесу за видом економічної діяльності, розроблено авторський підхід до класифікації ризиків з урахуванням специфічних умов сільськогосподарських підприємств. Ґрунтовно проаналізовано понятійний апарат термінології обраної теми. Проаналізовано та узагальнено фактори, які зумовлюють ризик у господарській діяльності аграрних підприємств. Авторами визначено особливості процесу управління ризиками в контексті менеджменту підприємств, його складові. Представлена оригінальна класифікація ризиків, з якими стикаються аграрні підприємства у процесі своєї господарської діяльності. Зроблено висновок, що запропонована класифікація може представляти практичний інтерес для господарюючих суб’єктів і використовуватися в якості моделі для створення власної кваліфікаційної таблиці з урахуванням галузевих особливостей агровиробництва та стати одним з інструментів при прийнятті управлінських рішень, щодо побудови ефективної системи ризик менеджменту на підприємстві.
ОРГАНІЗАЦІЯ ОБЛІКУ ДЕБІТОРСЬКОЇ ЗАБОРГОВАНОСТІ ТА ШЛЯХИ ЇЇ ВДОСКОНАЛЕННЯ
Authors: Кравченко Олена , Кобець Тетяна
Published: May 2021

У статті досліджено теоретичні та методологічні основи організації обліку дебіторської заборгованості. Розглянуто економічну сутність дебіторської заборгованості та її виникнення в сучасних умовах господарювання. Відображено класифікаційні ознаки щодо дебіторської заборгованості. Особливу увагу приділено питанням формування обліковій політиці в частині дебіторської заборгованості. Наведено її основні елементи, що потребують розкриття в Наказі про облікову політику підприємства. Згруповано фактори, які впливають на виникнення та збільшення дебіторської заборгованості на підприємстві. Визначено шляхи вдосконалення організації обліку дебіторської заборгованості через додаткові умови комерційного кредитування, введення аналітичних та субрахунків до робочого плану рахунків підприємства.
БАНКІВСЬКІ ДЕПОЗИТИ ТА ОВДП ЯК АЛЬТЕРНАТИВНІ ОБ’ЄКТИ ВКЛАДЕННЯ КОШТІВ
Authors: Матвійчук Наталія , Теслюк Софія , Боричевська Ірина
Published: May 2021

Здійснено комплексне порівняння ОВДП та банківських депозитів як інструментів вкладення коштів фізичних та юридичних осіб. Обгрунтовано значення ОВДП як боргового та монетарного інструменту в сучасних умовах та розглянуто структуру власників ОВДП. Здійснено порівняння портфелю ОВДП у власності фізичних осіб та депозитного портфелю фізичних та юридичних осіб. Обгрунтовано переваги ОВДП перед банківськими депозитами: високий ступінь надійності, відсутність оподаткування доходів, вища прибутковість та можливість зафіксувати дохідність на тривалий термін. Виокремлено основні перешкоди до інвестування в ОВДП (складна процедура придбання, високі трансакційні витрати, необхідність подання податкової декларації та високий поріг входження в цінні папери). Доведено, що для стимулювання вкладень в ОВДП потрібно скасувати подання декларацій та спростити ідентифікацію клієнта, використовуючи Bank ID.
ПАТЕНТНІ ПОШУКИ ЯК ІНСТРУМЕНТ ЗАБЕЗПЕЧЕННЯ НАУКОВО-ТЕХНІЧНОГО ПРОГРЕСУ ТА ЕКОНОМІЧНОГО ЗРОСТАННЯ
Authors: Олійничук Олександра
Published: May 2021

Стаття присвячена актуальним питанням проведення патентних пошуків. Розглянуто структуру та переваги патентної інформації. Узагальнено вітчизняні бази даних у сфері інтелектуальної власності, а також здійснено огляд баз даних інших країн та міжнародних організацій. Зроблено висновок, що світовою спільнотою напрацьовано ефективний механізм виконання патентних досліджень, що забезпечує ґрунтовність, всебічність, релевантність отриманих даних. Окреслено цілі патентних досліджень та типи патентних пошуків за різними базами даних, а саме на предмет актуальності винаходу та шляхів вирішення технічної проблеми; новизни винаходу; дійсності патенту; іменний патентний пошук; пошук на предмет непорушення прав третіх осіб. Обґрунтовано висновок про роль патентної інформації для забезпечення подальшого науково-технічного та економічного розвитку.
ДЕТІНІЗАЦІЯ ЕКОНОМІКИ ЯК СПОСІБ ЗБІЛЬШЕННЯ ПОДАТКОВИХ НАДХОДЖЕНЬ ДО БЮДЖЕТУ
Authors: Тарасенко Олена , Перетятько Валерія
Published: May 2021

В статті проаналізовано структуру зведеного бюджету України за доходами у 2018–2020 роках, проведено аналіз складу податкових надходжень у структурі зведеного бюджету України за доходами у 2018–2020 роках. У ході проведення дослідження було розглянуто розмір дефіциту державного бюджету за період незалежності України. Розглянуто зміни інтегрального показника рівня тіньової економіки в Україні і темпи приросту/ зниження рівня реального ВВП. Досліджено динаміку рівня тіньової економіки за окремими методами. Визна- чено причини наявності значних масштабів тіньової економіки. Було виділено основні інструменти тінізації фінансових потоків. В статті авторами представлено основні напрями щодо боротьби з тіньовою економікою, які забезпечать підвищення рівня податкових надходжень до бюджетів різних рівнів.
Metabolic Syndrome among Indigenous People (Orang Asli) in Peninsular Malaysia: A Systematic Review
Authors: ITHNIN MUSLIMAH , ARIPIN KHAIRUN NAIN NOR , Mohd Effendy Nadia , Juliana Norsham , Mohamad Nor Nadeeya ‘Ayn Umaisara , Mohd Rani Mohd Dzulkhairi
Published: May 2021

Metabolic syndrome is a cluster of conditions that increase the risk of developing chronic diseases. This paper aims to assess the data on metabolic syndrome among indigenous Orang Asli in Malaysia. Searches were carried out using electronic databases of CINAHL, Medline, PubMed, and Scopus using predefined keywords. Cross-sectional studies of metabolic syndrome using any clinical diagnosis criteria among adult Orang Asli in Peninsular Malaysia included. Fifteen studies with these criteria were selected, five with metabolic syndrome studies. The general prevalence (weighted mean) of metabolic syndrome in Orang Asli was 26.3% (range: 12.0–39.8). Metabolic syndrome was more frequent in females (30.0%) than in males (19.3%). The most common components of metabolic syndrome were low HDL-C levels (41.0%) and hypertension (33.7%). For abdominal obesity, high triglycerides, and abnormal glycemia, the prevalence was; 24.6%, 21.5%, and 14.0%, respectively. Conclusively, the present systematic review brings us closer to an understanding of the prevalence of metabolic syndrome among this vulnerable population. The methodological differences among the studies published limit a joint analysis of their results. Nevertheless, finding from this review shows their high prevalence of the metabolic syndrome is comparable with other ethnic groups in Malaysia that requires immediate attention from all related parties.
Heuristic Framework for Sustainable Cooling Water Systems Operations in Oil Facilities
Authors: Hashim Mustafa , Hassim Mimi Haryani , Ng Denny KS , Ng Denny KS
Published: May 2021

To meet the growing demand for cleaner environment from the society, most leading oil companies have committed to preserve environment via reduction of greenhouse gases, water and soil pollution as well as the use of natural resources. In most of the oil facilities, they required massive cooling systems to cool down process streams in order to meet the process requirements. The most common cooling system in oil facilities is evaporative cooling water system (ECWS) as such system has high efficiency. Cooling water is commonly used in offices and residential areas. However, the cooling water system is one of the utility systems that generates high environmental impacts due to high consumption of power, water and chemicals. Therefore, it is important to optimize the system in the early design stage of the project to operate in the most effective and efficient condition. In reality, many efforts may be missed out due to loose project definition, inexperience design engineer, hectic project schedule, or resource constraint. Therefore, in order to overcome the previous limitations, this paper presents a comprehensive heuristic improvement framework for cooling water systems in oil operating facilities.
Deployed Sustainable Strategies to Realize Benefits from Implementation of Energy Management Systems Across Company’s Multi Functioning Organizations
Authors: Hashim Mustafa , Hassim Mimi Haryani , Hassim Mimi Haryani , Ng Denny KS
Published: May 2021

Energy efficiency and conservation become an integral part of the business culture, and it simply means using less energy to perform the same tasks. Due to increasing internal demand on energy in many parts of the world, societal expectations for comprehensive approaches on energy efficiency have been forced into focus. As world energy demand soars, it is known that the manufacturing, power generation and transportation sectors are the main consumers to the intensive utilization of energy resources. The demand from the growing population has overwhelmed the current capacity. It is inevitable; therefore, many oil companies are now participating in on-going efforts to conserve energy, and do so in a sustainable manner by means of implementing energy management systems (EnMS) in accordance to internationally recognized standards. However, its progress has just been seen, and unfortunately, most of the oil companies are far away from matured management to excel in energy performance. Most of the oil companies consider EnMS as ambition and certificate on the wall rather than a driving vehicle to become a reference company. In fact, cost reduction is the main focus rather than to explore other hidden benefits of EnMS. More seriously, lack of dedicated measures and right strategies to push for the successful implementation. This paper discusses proven strategies that drive for full realization of EnMS benefits.
An Illegal Dumping Detection System Based on Image Processing in OpenALPR
Authors: Wan Ismail Wan Zakiah
Published: May 2021

Tipping or depositing large waste onto land using unauthorized and unlicensed methods are considered as illegal dumping. The increasing rate of illegal dumping becomes a crucial nation issue because this activity causes negative impacts to social, economy and environment. Thus, study on detecting the dumping activities is conducted to control the illegal dumping activities in Malaysia. Raspberry Pi with Python language is used as the microprocessor and a Raspberry Pi camera module with a microwave radar sensor are interfaced to it to capture the image of any vehicles entering the illegal dumping site. The image is captured to recognize the license plate of the vehicle. The method in this study is by using Open Automatic License Plate Recognition (ALPR), Open Computer Vision (CV) libraries and Optical Character Recognition (OCR) to detect the character of the plate registration number. The outcome of the study consists of recognition of Malaysia vehicles’ plate number and the automatic real time email notification on the illegal dumping case. The detection system can be used for case monitoring since the plate number recognition is done in real time. The system can be upgraded to ensure its sustainability in the harsh and isolated environment.
Increase in Warpage Prediction Accuracy for Glass Filled Polyamide Material (PA66) through Integrative Simulation Approach
Authors: Gaval Vivek Ramdas , Divekar M , Wonisch A , Jadhav G
Published: May 2021

The warpage prediction accuracy of the simulation software depends on part geometry, material model and methodology. However, the material model in the existing simulation software’s does not consider factors such as nonlinear mechanical properties, temperature dependent behaviour, viscoelastic behaviour and transient description of warpage leading to less accuracy. Using an integrative simulation approach, BASF has developed Ultrasim® tool to overcome limitations in the material model of existing simulation software. In the new material model thermomechanical properties, stress relaxation behaviour and nonlinear mechanical properties were considered and this new material model is added to Ultrasim® tool. The model also considers time dependent descriptions of the warpage starting from packing phase of the moulding process, followed by actual ejection and cooling. In this paper warpage results predicted through new integrative simulation approach and existing simulation approach are compared with actual experimental results for 50% glass filled polyamide material (Ultramid®A3WG10). The results revealed that warpage values predicted by integrative simulation based Ultrasim® tool are closer to actual experimental results compared to values predicted by existing simulation technologies. Therefore an integrative simulation approach can be used prior to making real parts to reduce manufacturing cost.
Estimation of Student Satisfaction and Student Loyalty in Indian University offering Higher Education
Authors: Gaud Dhaval , Zaveri Bijal
Published: May 2021

Thanks to its multidimensional nature and ultimate effect on customer retention, consumer engagement, and finally, firm efficiency, service value has gained a lot of attention in recent marketing literature. The findings indicate as the service value dimensions functional value, consumer satisfaction, service efficiency, appurtenant value, image, and social value. This study supports the notion that higher education institutes can achieve a competitive advantage by focusing on value for service.
The Frequency and Spectrum of Bacterial Contamination of Packed Red Blood Cells and Platelet Concentrate Units from a Sample of Iraqi Blood Donors
Authors: Khazal Ali
Published: May 2021

Bacterial contamination of donated blood is defined as the presence of bacteria in the blood components which are collected and/or processed for transfusion. It is the second cause of death beyond ABO-mismatch. The aims were to determine the frequency of bacterial contaminations in stored packed RBC and platelet concentrate units. This cross-sectional study was conducted in Baghdad between 2nd of September to 27th of December 2019. Two hundred samples; 100 samples from packed RBC units and 100 samples from platelet concentrate units were randomly selected. There were 38/100 of platelet concentrate units found to be contaminated, while 28/100 samples studied of packed RBC units were contaminated by bacteria. The high rate of contamination of samples presented. Gram-positive bacteria were the most predominant, and this attributed to poor skin cleansing and antiseptic techniques used prior to donor blood collection.
ENVIRONMENTAL JUSTICE AND INCLUSIONS: Inaugural Editorial
Authors: Hossain Kamrul
Published: May 2021

The environmental agenda encompasses a relatively large number of issues having multiple actors involved in and around them. Environmental problems are diverse and complex, both in local as well as in international settings. The complexity of environmental problems often involves exploring various solution approaches. The regulatory process is one of them; and the policy process complements regulatory developments. They guide human behaviour. Given that human interactions with nature and ecological processes are central to environmental problems, law and policy regulations suggest changing human behaviour in order to be in harmony with nature and to better cope with natural processes. Coping with natural processes does not mean seeking the adoption of preventive measures only. Rather, positive and proactive measures are necessary to recover from environmental harm, as we have already caused significant damage to our environment. We must recover from the injury caused to our planet in order for it to exist in its unique condition and to continue with life support systems that are sustainable. Law and policies are some of the tools we employ to recover from the damages caused to our environment. Since the 1972 Stockholm Conference on the Human Environment, the environmental agenda has predominantly captured our attention on all decision-shaping and decision-making levels, including political, economic, scientific, and cultural spheres both in academic and non-academic contexts. The actors' joint efforts have provided us with a mutual understanding of environmental problems, a set of agreed-upon norms and principles, and procedural practices to respond to such problems.
THE INFLUENCE OF THE COMPOSITION OF MINERAL WATERS ON THE ORGANISM OF WORKERS INVOLVED IN INSTALLATION OF INSULATION
Authors: Skrypnyk O. , Abrakitov V. , Ivashchenko M.
Published: May 2021

The use of modern thermal insulation materials in construction is one of the additional sources of harmful production factors and also lead to the formation of fine dust. To date, the risk of loss of health of workers in the construction industry in contact with mineral wool is little studied. To reduce the risk of health of workers in the construction industry, it is necessary to give a comprehensive assessment of harmful factors of the production environment when using mineral wool in the technological process and justify measures to improve working conditions.
The paper provides information on a widely used in the construction industry insulation material - mineral wool. Its chemical composition is given. The main unfavorable factors of the working environment are revealed.
In the construction industry, one of the most pronounced harmful production factors is the formation and release of dust, which is an aerosol of predominantly fibrogenic action.
The development of the construction industry, the introduction of new insulation materials in the construction of industrial buildings, installations and structures, as well as residential and public buildings lead to new, insufficiently studied factors of the production environment that affect the health of workers and may increase the risk of health loss. To date, information on the effects of mineral wool on the body of workers and the toxicological characteristics of different types of mineral wool are fragmentary.
The chemical composition of the dust determines the nature and severity of the adverse effects of dust. The dispersion composition of the dust determines the depth of penetration of particles into the respiratory organs of workers. The stability of dust particles in the air of the working area, their concentration, shape and duration of exposure determine the dust load and the risk to the health of workers. Dust particles can sorb on their surface other pollutants, which both in the complex and in isolation pollute the air of the working area and have an adverse effect on workers.
An important criterion for the safety of mineral wool under inhalation is the dispersion of the dust formed. It is generally accepted that the most dangerous mineral wool dust with a dispersion of 3 microns or less.
CONCEPT OF INFORMATION TECHNOLOGIES IN CONSTRUCTION AND DIRECTIONS OF THEIR DEVELOPMENT IN UKRAINE
Authors: Druzhinin A. , Davidenko O. , Bratishko S. , Zhyliakova H.
Published: May 2021

The analysis of the main provisions of two concepts: "The concept of application of construction information modeling in the management of the life cycle cost of public facilities" (Project) was developed at the National Academy of Public Administration under the President of Ukraine (NASU) by a group of experts led by Professor V.S. Kuybida and “Concept of Implementation of BIM - Construction Information Modeling in Ukraine” (Project) of the EU International Technical Assistance “Assistance to the Organization of the Government of Ukraine in Improving the Management of the Infrastructure Project Cycle”.
The developers of the first Concept identified the principles, but the implementation of these principles in Ukraine requires the improvement of the current system of relations in the investment-construction-operational process, changes the traditional mechanisms of the industry and construction management through innovation.
The second Concept presents the results of a comprehensive study in general of the problems of implementation of information technology, without a deep study of the state of the construction industry of Ukraine.
The analysis of the main provisions of the two concepts allowed to identify the principles that should be the basis for combining three life cycle models: design, construction, operation - from the first stage of design to the reconstruction or liquidation of the object, in order to use them to innovate and improve competitiveness of objects at all stages of a life cycle and influence on work of the construction enterprises in market conditions.
The educational component of the Concept as a whole does not cause objections, but requires specification of a number of decisions at the level of the Ministry of Education of Ukraine, universities, specialties and departments. In general, the combination of the two concepts provides a lot of historical and methodological material for the educational process and can be the basis for the educational process of information technology. Simultaneously, the analysis of the two concepts requires attention to differences, conclusions and generalizations that contradict the real situation in the industry and require a single system of terms.
HISTORICAL ORIGINS OF THE FORMATION OF THE CHINESE ECONOMIC MODEL
Authors: Reshetilo V.
Published: May 2021

The article analyzes the history of formation, main features, characteristics and stages of development of the Chinese economy, which has been demonstrating economic growth over the past decades. The country's economic success is updated by research on the historical origins, place and role of the Chinese economic model in global economic development. In the historical context, the origins of the Chinese model of economy are seen in the main features of the Asian mode of production, the constant presence of the state in the regulation of public life and in economic development.
It is characterized that the formation of the Chinese model of the economy began with the economic reforms of 1978, the features of which were focused only on economic changes with an unchanged political system; the absence of any privatization and the creation of private enterprises from scratch during market reforms; the leading role state regulation and national economic plans in the development of the economy. The characteristic features of the modern Chinese model of the economy include: a strong state with a large-scale public sector of the economy; active state intervention in macroeconomic regulation, planning and forecasting of socio-economic development; a multi-layered economy, an effective combination of various forms of ownership, a combination of traditional and modern ways of life; the implementation of the Confucian model of a just state, which should create equal opportunities for self-development of everyone; the special role of national mentality, traditions and Customs; a high level of disciplinary culture and stable organization of society; the dominance of pragmatism and rationalism.
It is investigated that the most important feature of the Chinese economic model is the development of the real sector of the economy, and the main tools of global competition are considered here new technologies and innovative industries that are supported by government programs.
METHOD OF MODELING AND FACTOR ANALYSIS OF LABOR PRODUCTIVITY
Authors: Kostiuk V. , Milkin I.
Published: May 2021

The article deals with the method of modeling and factor analysis of labor productivity. It has been emphasized that labor productivity is one of the most important indicators characterizing the operation and performance of any enterprise. In the system of generalizing indicators of production efficiency, this indicator occupies a special position since it characterizes the achieved level of development of the material and technical foundation of production, efficient use of production potential, and technological advances. It has been emphasized that the change of this indicator depends on various factors characterizing the efficiency of labor and technical potential of an enterprise. Thus, the factor analysis of this indicator is crucial, i.e. studying the influence of structural and production factors on its change. The efficiency of the use of fixed assets, in particular production equipment, has a decisive influence on the change of labor productivity. The most efficient use of machinery and equipment contributes to a significant increase in performance. The article emphasizes that a crucial means of analytical research is the modeling of this indicator. In the course of modeling factor systems of labor productivity, it is necessary to consider the key factors characterizing the structure and efficiency of labor and technical potential of an enterprise, which directly influence the change of the labor productivity of an employee. This is, first of all, the enterprise personnel structure (the number of workers out of the total number of employees), the average output of one worker, labor capital, capital efficiency of fixed assets, their active part, utilization rates of production equipment, and the productivity of existing equipment. To understand the impact of the above factors on the change of productivity of one employee, a step-by-step factor analysis, using the method of chain substitution, has been suggested. The given method of modeling and factor analysis of labor productivity makes it possible to determine the influence of crucial factors on the change of this indicator, study the patterns of such influence, identify internal growth reserves, and ground appropriate managerial decisions on further use of labor and material resources of an enterprise.
Rancang Bangun Sistem Informasi Penjualan Sparepart Berbasis Web
Authors:   Sekolah Tinggi Teknologi Garut, Fatimah Dini Destiani Siti , Atmadja Aldy Rialdy , Habibulloh Nurfikri
Published: May 2021

Toko sparepart motor adalah sebuah penjualan atau pelayanan service motor yang berkaitan dengan setiap elemen pada bagian motor. Toko sparepart ini dalam melakukan penjualan masih dengan cara manual yaitu penulisan untuk setiap melakukan transaksi masih dengan cara lama seperti pencatatan dalam buku, yang akan membutuhkan waktu yang lama untuk sekali setiap transaksi. Inti permasalahan ini dibuatkan sistem informasi penjualan barang yang berisi data penjualan, stok barang serta laporan transaksi penjualan setiap hari.. Yang dicapai dari penelitian ini yaitu pada sistem informasi penjualan sparepart diharapkan mampu memberikan gambaran pada pihak toko dalam proses penjualan atau transaksi sparepart motor. Penggunaan sistem informasi penjualan di toko sparepart ini, bisa meng efektifkan waktu dalam pemecahan masalah yang ada pada toko sparepart
Rancang Bangun Media Pembelajaran Sistem Pernapasan Menggunakan Marker-Based Augmented Reality
Authors:   Sekolah Tinggi Teknologi Garut, Tresnawati Dewi , Desfriansyah Muhamad Firzan
Published: May 2021

Perkembangan teknologi pada saat ini khususnya pada teknologi augmented reality dapat menunjang media pembelajaran. Teknologi augmented reality yang diterapkan pada media pembelajaran dapat meminimalisir kejenuhan saat pembelajaran yang dirasakan oleh peserta didik karena media belajar yang ada masih berupa buku teks yang terpaku pada gambar atau tulisan saja. Dengan adanya media pembelajaran sistem pernapasan menggunakan teknologi augmented reality ini merupakan bentuk inovasi pembelajaran sebagai alternatif alat peraga edukatif. Aplikasi media pembelajaran ini memiliki fitur augmented reality yang dapat menampilkan sistem pernapasan dengan bentuk 3 dimensi pada layar smartphone dan terdapat teks berupa materi sistem pernapasan, gambar, audio, animasi demi terciptanya antusias peserta didik serta meningkatkan pemahaman tentang sistem pernapasan. Media pembelajaran ini mencakup materi tentang organ sistem pernapasan, mekanisme sistem pernapasan, penyakit pada organ sistem pernapasan dan cara menjaga kesehatan organ sistem pernapasan. Media pembelajaran ini dibangun dengan metodologi Research and Development yang terdiri dari 5 tahapan yaitu analysis, design, development, implement, dan evaluation. Media pembelajaran ini diharapan dapat memudahkan peserta didik dalam pemahaman mata pelajaran ilmu pengetahuan alam tentang sistem pernapasan serta dapat membantu sebagai alternatif alat peraga edukatif yang meningkatkan minat, semangat belajar dan pemahaman peserta didik.
Rancang Bangun Aplikasi Media Pembelajaran Budidaya Burung Kicau Cucak Rawa, Murai Batu, dan Anis Merah Berbasis Android
Authors:   Sekolah Tinggi Teknologi Garut, Rahayu Raden Erwin Gunadhi , Cahyadi Iqbal Dwiki
Published: May 2021

Burungimerupakannsalah satu jenis hewannpeliharaan yang banyak digemari masyarakat saat ini. perlu upaya-upaya strategis untuk penyelamatan dan pelestarian burung dari ancaman yang membahayakan populasinya di alam serta peningkatan kesadaran masyarakat. upaya strategis untuk penyelamatan dan pelestarian burung dari ancaman kepunahan di alam bisa dilakukan dengan cara budidaya burung tersebut. informasi mengenai pembelajaran budidaya burung masih menggunakan metode konvesional dan buku yang dirasa kurang menarik dan praktis. Multimediakdigunakanpuntuklbanyak digunakan, dari hiburan sampai pembelajaran yang dikemas secara menarik dan praktis. Penelitian ini bertujan untuk merancang bangun aplikasi media pembelajaran budidaya burung kicau, cucak rawa, murai batu, dan anis merah. manfaat dari penelitian ini berupa aplikasi yang diharapkan mampu mempermudah penyampaian infromasi mengenai pembelajaran agar masyarakat khususnya penghobi burung dapat mengetahui pemilihan jenis, pemilihan burung, cara merawat, penyakit pengobatan, pengembangbiakan dan kandang/sangkar. Metodologi yang digunakan dalam pembuatan aplikasi media pembelajaran ini menggunakan metodologi Multimedia Development Life Cycle terdiri dari enam tahapan, yaitu concept, design, material collecting, assembly, testing, dan distribution. Penelitian ini didapatkan hasil berupa aplikasi media pembelajaran budidaya burung kicau cucak rawa, murai batu, dan anis merah menggunakan teknologi multimedia untuk penerapan pada platform android.
Pelaksanaan Kegiatan Ekstrakurikuler Tari Tradisional di Taman Kanak-kanak Sani Ashila Padang
Authors: Utami Winda Trimelia , Yeni Indra , Yaswinda Yaswinda
Published: May 2021

Kegiatan ekstrakurikuler merupakan penunjang dari kegiatan akademik di lembaga PAUD. Hal ini perlu diterapkan diseluruh lembaga ini. Oleh karena itu penelitian ini bertujuan untuk mengetahui pelaksanaan kegiatan ekstrakurikuler tari tradisional di Taman Kanak-kanak Sani Ashila Padang dalam rangka mengetahui penerapannya. Metode penelitian yang digunakan adalah deskriptif dengan pendekatan kualitatif. Hasil penelitian menunjukkan bahwa kegiatan ekstrakurikuler tari tradisional di TK Sani Ashila Padang belum sesuai dengan tahap-tahap pengenalan tari kepada anak. Namun dengan latihan yang rutin dapat mengantarkan TK Sani Ashila Menjuarai beberapa Lomba Tari. Melalui kegiatan ini juga sebagai wahana untuk memperkenalkan kebudayaan pada anak dan juga untuk membantu perkembangan motoriknya. Kendala yang sering terjadi adalah suasana hati anak yang berubah drastis, sehingga guru harus membujuk anak agar bersemangat kembali. Tempat latihan yang digunakan berukuran 4x4 m tidak sebanding dengan jumlah anak yang mengikuti kegiatan. Dari penelitian ini disimpulkan bahwa pelaksanaan kegiatan ekstrakurikuler tari tradisional di Taman Kanak-kanak Sani Ashila Padang belum berjalan dengan baik.
Mujeres-madres-migrantes de Guatemala en la frontera sur de México
Authors: Ramírez Ramos Laura Itzel , Nazar Beutelspacher Dominga Austreberta , Zapata Martelo Emma , Sánchez Ramírez Georgina , Salvatierra Izaba Benito
Published: May 2021

The concept of motherhood is discussed as a gender device that creates processes of disadvantage and vulnerability. The results presented in this article were generated and analyzed using the biographical method. Through the testimonies of six Guatemalan migrant women, it is shown how the individual experience is interwoven with the historical reality of a given time and space. It is concluded that motherhood, exercised in contexts of inequality, and during migratory processes, is mediated, regulated, and sanctioned by institutions that affect and determine the quality of life of women-mothers-migrants.
In Search for Land and Water: From Chihuahua, Mexico, to Santa Cruz, Bolivia
Authors: Manzanares Rivera José Luis
Published: May 2021

This article analyzes the Mennonite migration process from the arid plains of Chihuahua in northern Mexico to South America’s Santa Cruz in Bolivia, associating intensive use of underground water resources to migration as a trigger. The analysis in this research suggests that the Mennonite migration model has found social conditions in Latin American countries, particularly in their transition from Mexico to Bolivia, that has allowed it to flourish. The results indicate opportunities for devising social integration policies that promote environmental sustainability at the Mennonite migration host communities.
Arap Hazar Savaşları ve Derbent
Authors: NECİYEV Elçin , AHMEDOV Meherrem
Published: May 2021

Derbent antik şehri, Azerbaycan'ın en önemli şehirlerinden biri olarak bilinmektedir. Derbent'in jeostratejik konumu, yabancı işgalcilerin dikkatini sürekli çekmiştir. Şehir, Sasani-Hazar ve Arap-Hazar savaşlarında belirleyici bir konumunda olmuştur. Arap-Hazar savaşları yaklaşık 100 yıl sürmüştür. Derbent, Azerbaycan topraklarına saldıran Hilafet ordularının dikkat odağındaydı. Derbent'e ilk saldırının Halife Ömer b. Hattab (634-644) saltanatı sonunda başlamış olmasına rağmen, Halife Hişam b. Abdülmelik (724-744) dönemine kadar Araplar Derbent'te egemenliklerini koruyamamışlardır. Makalede, kaynak ve araştırmalara dayanılarak Arap-Hazar savaşlarında şehrin rolü ve önemine vurgu yapılmaktadır.
Robin Criterion on Divisibility
Authors: Vega Frank
Published: May 2021

Robin criterion states that the Riemann Hypothesis is true if and only if the inequality $\sigma(n) < e^{\gamma } \times n \times \log \log n$ holds for all $n > 5040$, where $\sigma(n)$ is the sum-of-divisors function and $\gamma \approx 0.57721$ is the Euler-Mascheroni constant. This is known as the Robin inequality. In 2007, Choie, Lichiardopol, Moree and Sol{\'{e}} have shown that the Robin inequality is true for all $n > 5040$ which are not divisible by $2$. We prove that the Robin inequality is true for all $n > 5040$ which are not divisible by any prime number between $3$ and $953$.
Maternal Lead Exposure Impairs Offspring Learning and Memory via Decreased GLUT4 Membrane Translocation
Authors: Zhao Zai-Hua , Du Ke-Jun , Wang Tao , Wang Ji-Ye , Cao Zi-Peng , Chen Xiao-Ming , Song Han , Zheng Gang , Shen Xue-Feng
Published: May 2021

Graphical Abstract
Co-expression Network Revealed Roles of RNA m6A Methylation in Human β-Cell of Type 2 Diabetes Mellitus
Authors: Chen Cong , Xiang Qing , Liu Weilin , Liang Shengxiang , Yang Minguang , Tao Jing
Published: May 2021

RNA m6A methylation plays an important role in the pathogenesis of type 2 diabetes mellitus (T2DM). RNA modifications and RNA-modifying regulators have recently emerged as critical factors involved in β-cell function and insulin resistance, including “writers,” “erasers,” and “readers.” However, their key roles in regulating gene expression in T2DM remain unclear. The construction of co-expression network could provide a cue to resolve this complex regulatory pathway. We collected the transcriptome datasets of β-cell in diabetic patients, calculated the partial correlation coefficient, excluded the influence from control variables of diabetes related genes, and identified the genes significantly co-expressed with m6A regulators. A total of 985 genes co-expressed with m6A regulators (Co-m6AR) were identified, which were enriched in metabolic process, MAPK and EGFR signaling pathways. Some of them have been confirmed to play a pivotal role in T2DM, including CCNL2, CSAD, COX5A, GAB2, and MIRLET7I, etc. Further, we analyzed the m6A modification characteristics of Co-m6AR in β-cell and identified 228 Co-m6AR containing m6A methylation sites, involving in several key signaling pathways regulating T2DM. We finally screened out 13 eQTL-SNPs localized in Co-m6ARs, and 4 have been reported strongly associated with diabetes, including GAB2, LMNB2, XAB2, and RBM39. This co-expression analysis provides important information to reveal the potential regulatory mechanism of RNA m6A methylation in T2DM.