bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluations of Emotion Analysis of Tweets using Bidirectional Long Short Term Memory and Conventional Machine Learning
Authors: Kurniasih Aliyah , Santoso Aloysius Kurniawan , Wicaksono Bagus Dwi , Pardede Hilman F
Published: August 2024

Many ideas are contained in the social media twitter as a form of expression for an event. This review can be used to determine a person's emotions based on text data so that we can determine the next action in addressing and responding to that opinion. Emotion classification on twitter can be done by recognizing the tweet text pattern of the user. In this study, representing emotions using the BiLSTM model and the Conventional Machine Learning model. The amount of learning rate and the number of layers and the optimizer used and the number of epochs in the BiLSTM model can affect the accuracy results. In the conventional machine learning model, the K value of the KNN, the selection of the naive bayes model on probalistic, and the Decision Tree variation in the values of Max-depth, min-leaves, min-split will affect the results of the accuracy value. So that we get a good model for the classification of emotional sentiments based on text data from an opinion on the tweets page.
Studying the proliferation activity of the plant ?aper (Capparis spinosa L.)
Authors: Khalilova Sevara , Feofanova Nataliya , Dushanova Gavkhar , Kan Svetlana , Ashurova Guljakhon
Published: August 2024

The article presents information on the methods and results of studying the influence of extracts prepared from various organs of the caper plant (Capparis spinosa L.), which in the Samarkand region exhibits the absence of proliferative activity of monocyte macrophages and mouse RAW 264.7. There are many scientific and research works devoted to the study of the medicinal properties of Capparis spinose L. cappers growing in Uzbekistan, as well as many works dedicated to identifying the molecular mechanisms of the immunomodulatory properties of the plant, which have not yet been studied. In medicine, consuming ripe fruits of C. spinosa L. has long been known to treat various diseases' inflammatory processes, including stomach inflammation and intestinal bleeding processes of haemorrhoids. The experiments show that concentrations of plant extracts at a concentration of 25.5 ?l have a destructive effect on all samples. A concentration of 1 ?l reduces the proliferative activity of cells of all plant extracts, except for seed extract; as a result, when exposed to 1 ?l of seed extraction, the population level was the highest. In cells stimulated with LPS, the level of proliferation was high at a concentration of 0.5 ?l of extracts of flowers, fruits and roots. Cytotoxicity was observed in extratax leaves, which may explain the antibacterial activity.
Investigation of the operating characteristics of diesel engines with chromium oxide (Cr2O3) nanoparticles dispersed in Mesua ferrea biodiesel: an experimental and predictive approach using ANNs and RSM
Authors: Kari Jagadish , Varaha Siva Prasad Vanthala , Sagari Jaikumar
Published: August 2024

This study investigates the effects of using biodiesel from Mesua ferrea (BD20) and chromium oxide (Cr2O3) nanoparticles in diesel engines. The Response Surface Methodology (RSM) model and artificial neural networks (ANNs) were developed to make precise predictions of the operating parameters. The amount of Cr2O3 nanoparticles was set at 80 mg/L, and surfactant and dispersant were applied to the nanoparticles in the same amounts. The study was carried out with different compression ratios and load conditions. The parameters evaluated were engine load, fuel samples and compression ratio as inputs and BTE, BSFC, CP, NHRR, CO, UHC, NO
x
and smoke opacity as outputs. The addition of the QPAN80 additive at the same dosage of 80 mg/L together with the BD20 fuel blend containing Cr2O3 at a concentration of 80 mg/L resulted in a significant increase in BTE by 16.58 % and a reduction in BSFC by 0.58 %. While the NHRR increased by 85.40 %, the CP increased sharply by 24.47 %. The CO concentration decreased by 31.85 %, the UHC concentration by 22.22 %, the NO
x
concentration by 6.16 % and the smoke emission by 62.61 %. For each output parameter, the correlation coefficient (R
2), calculated using ANNs and RSM was between 0.96 and 0.98. The observed range of values demonstrates a robust correlation between the experimental data and the predicted outcomes.
Social vulnerability and prenatal diagnosis
Authors: Kouba Insaf , Del Pozzo Jaclyn , Alvarez Alejandro , Keller Nathan A. , Palmer Alexis , Bracero Luis A. , Blitz Matthew J.
Published: August 2024

Objectives

There are limited data on how neighborhood-level risk factors affect the likelihood of having prenatal diagnosis. Neighborhood social vulnerability can be quantified and ranked using the social vulnerability index (SVI), a tool that measures the cumulative effect of external stressors in the local environment that may affect health outcomes. The objective of the study was to determine the relationship between SVI and prenatal diagnosis among pregnant patients who received genetic counseling.

Methods

Retrospective cohort study of all pregnant patients who had genetic counseling at two hospitals in New York between January 2019 and December 2022. For each patient, the address of residence was linked to an SVI score (primary exposure) based on census tract. SVI scores were subdivided into fifths and analyzed categorically. The primary outcome was prenatal diagnosis (yes/no). Multivariable logistic regression was performed.

Results

A total of 5,935 patients were included for analysis and 231 (3.9 %) had prenatal diagnosis. On regression analysis, no association between SVI and prenatal diagnosis was observed. Patients who had a diagnostic procedure were more likely to be English speaking (aOR 1.80; 95 % CI 1.13–2.87), carriers of a genetic disorder (aOR 1.94; 95 % CI 1.32–2.86), had increased NT (aOR 6.89; 95 % CI 3.65–13.00), abnormal NIPS (aOR 9.58; 95 % CI 5.81–15.80), or had fetal structural anomalies (aOR 10.60; 95 % CI 6.62–16.96). No differences were seen based on race and ethnicity group, insurance type, or marital status.

Conclusions

SVI score does not affect rate of prenatal diagnosis. Findings may differ in other geographic regions and populations.
Request for confirmation sequences in Low German
Authors: Weber Kathrin
Published: August 2024

This article examines request for confirmation (RfC) sequences in Low German (LoG) conversation, a dialect variety of German. The study is based on both a quantitative analysis of 200 RfC instances and a qualitative analysis of selected excerpts in the framework of conversation analysis (CA). As for the question design of RfCs, declarative and phrasal formats, as well as modulations and tags prevail in the LoG data. Concerning the response design, LoG is characterized as a polarity system in which language contact with the high variety plays a decisive role in the answer possibility space. In particular, High German response tokens are predominantly used as unmarked response types, while LoG response tokens are deployed as marked types. Moreover, LoG seems to be a language between the poles of token- and repeat-type languages. Full repeats index different degrees of ‘markedness’ in LoG interaction. Contrary to previous studies on polar answers, repeats in LoG are frequently deployed as unmarked responses in subordinate lines of actions. Repeats are also used as more marked answers after understanding displays. This article attempts to stress the importance of investigating non-standard languages and variety contact in CA, thereby addressing the monolingual bias in research on polar questions.
Invariant analysis of the multidimensional Martinez Alonso–Shabat equation
Authors: Abbas Naseem , Hussain Akhtar , Waseem Akram Muhammad , Muhammad Shah , Shuaib Mohammad
Published: August 2024

This present study is concerned with the group-invariant solutions of the (3 + 1)-dimensional Martinez Alonso–Shabat equation by using the Lie symmetry method. The Lie transformation technique is used to deduce the infinitesimals, Lie symmetry operators, commutation relations, and symmetry reductions. The optimal system for the obtained Lie symmetry algebra is obtained by using the concept of the adjoint map. As for now, the considered model equation is converted into nonlinear ordinary differential equations (ODEs) in two cases in the symmetry reductions. The exact closed-form solutions are obtained by applying constraint conditions on the symmetry generators. Due to the presence of arbitrary functional parameters, these group-invariant solutions are displayed based on suitable numerical simulations. The conservation laws are obtained by using the multiplier method. The conclusion is accounted for toward the end.
Untersuchungen zur Mindestspanungsdicke beim kryogenen Hartdrehen von Wälzlagerstahl
Authors: Grossmann Felix , Kirsch Benjamin , Uebel Julian , Seewig Jörg , Aurich Jan C.
Published: August 2024

Cryogenic hard turning is used for finishing AISI 52100. Its high hardness, good strength and wear resistance make it ideal for the use in rolling technology. If no post-processing is carried out, a good surface finish must be achieved by turning at low cutting depths and feed rates. This paper analyzes the process forces and temperatures as well as the resulting surface roughness during cryogenic hard turning of AISI52100. The results indicate that the minimum chip thickness lies between 10 and 25 μm.
Hochpräzise Funktionsflächen an CFK-Bauteilen
Authors: Kilian Leonie , Fehn Patrick , Bischop Floyd Daniel , Brouschkin Alexander , Dege Jan Hendrik , Krause Dieter , Weigold Matthias
Published: August 2024

With increasing demands on the power density of electrical drive systems metal materials commonly used in mechanical engineering are reaching their performance limits. Further improvements can be achieved using carbon fiberreinforced polymers (CFRP). To enable their use in industrial practice, the SPOTLIGHT project focuses on the manufacturing and grinding of high-precision functional surfaces of CFRP components. The CFRP components are evaluated through drive technology demonstrators.
Prozesssicheres Zerspanen –auch bei instabilen Bedingungen
Authors: Beckenlechner Robert , Rossaint Jens
Published: August 2024

Unstable conditions lead to increased vibrations in the machining process. The greater the vibration, the worse the surface quality and the higher the tool wear. This article shows the influence of various stability parameters and derives tips for process stabilization in practice. The manufacturer‘s information on cutting parameters, which are usually based on optimal conditions, play a crucial role.
Chronic Stress Alters Synaptic Inhibition/Excitation Balance of Pyramidal Neurons But Not PV Interneurons in the Infralimbic and Prelimbic Cortices of C57BL/6J Mice
Authors: Rodrigues Diana , Santa Cátia , Manadas Bruno , Monteiro Patrícia
Published: August 2024

The medial prefrontal cortex (mPFC) plays a pivotal role in regulating working memory, executive function, and self-regulatory behaviors. Dysfunction in the mPFC circuits is a characteristic feature of several neuropsychiatric disorders including schizophrenia, depression, and post-traumatic stress disorder. Chronic stress (CS) is widely recognized as a major triggering factor for the onset of these disorders. Although evidence suggests synaptic dysfunction in mPFC circuits following CS exposure, it remains unclear how different neuronal populations in the infralimbic (IL) and prelimbic (PL) cortices are affected in terms of synaptic inhibition/excitation balance (I/Eratio). Here, using neuroproteomic analysis and whole-cell patch-clamp recordings in pyramidal neurons (PNs) and parvalbumin (PV) interneurons within the PL and IL cortices, we examined the synaptic changes after 21 d of chronic unpredictable stress, in male mice. Our results reveal distinct impacts of CS on PL and IL PNs, resulting in an increasedI/Eratio in both subregions but through different mechanisms: CS increases inhibitory synaptic drive in the PL while decreasing excitatory synaptic drive in the IL. Notably, theI/Eratio and excitatory and inhibitory synaptic drive of PV interneurons remained unaffected in both PL and IL circuits following CS exposure. These findings offer novel mechanistic insights into the influence of CS on mPFC circuits and support the hypothesis of stress-induced mPFC hypofunction.
Transient synovitis associated with leuprolide depot (Lupron)
Authors: Steen Erica A , Phillips Susan A
Published: August 2024

A 6.6-year-old female presented to endocrinology with precocious puberty for evaluation and management. Workup was initiated, and a diagnosis of central precocious puberty was confirmed. A decision was made to initiate pubertal blockade using gonadotropin-releasing hormone agonist (GnRHa) therapy with depot leuprolide acetate injections every 3 months. The patient received the first depot leuprolide acetate injection in the right ventrogluteal area. Six hours following the injection, the patient was reported to be inconsolable in pain, which was localized to the right hip site of the earlier injection and associated with a refusal to ambulate. The pain and discomfort continued to progress over the next 24 h despite an alternating regimen of Tylenol and ibuprofen prompting admission to the emergency department. Vital signs demonstrated a low-grade fever and elevated C-reactive protein. An ultrasound of the right hip demonstrated fluid accumulation within the joint. Over the next week, the patient was unable to walk independently and required assistance for activities of daily living. By 2 weeks after the injection, the pain began to remit, and the patient resumed activities of daily living. Following consultation with allergy, a decision was made to continue GnRHa suppressive therapy with an alternative analog (Triptodur). The patient tolerated subsequent treatment without reaction.

Learning points

Although gonadotropin-releasing hormone agonists (GnRHa) have a generally good safety profile, there is a history of both local and systemic hypersensitivity reactions associated with their use.

Despite the long-acting formulation of depot leuprolide acetate, the systemic reaction in this case appears to be self-limited.

Discontinuation of therapy or a change to an alternative formulation of GnRHa analog should be considered based on the need for therapy versus the potential risk of rechallenge.
Lithuanian book science in 450th year of the First Lithuanian Book
Authors: Kaunas Domas
Published: August 2024

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Liturgic calendars in the Vilnius University Library
Authors: Krakytė Asta
Published: August 2024

L'article est consacré à la discussion sur la collection nommée Rubrice/lce du département des livres rares de la Bibliothèque de l'Université de Vilnius. On décrit la structure et l'histoire de la collection. On analyse le contenu et l'usage des publications qui la composent. On aborde le problème de l'usage du terme latin rubrice/la dans la langue scientifique lituanienne.
La collection a été constituée en 1929-1939 pendant la période polonaise de l'Université de Vilnius. En 1955-1956, cette collection a été complétée par les livres reçus de la Bibliothèque de l'Université de Kaunas et encore une fois en 1973-1974 par les exemplaires provenant d'autres fonds de la Bibliothèque de l'Université de Vilnius.
Actuellement, la collection contient plus d'un millier de publications périodiques des XVIIe au XXe siècles. Les titres latins sont très divers : Ordo divini officii recitandi missaeque celebrandi, Directorium divini officii, Agenda ecclesiastica, Kalendarium ecclesiasticum, Rubricella, etc. Ces livres sont une sorte de calendriers liturgiques qui indiquent les offices de l'Église tous les jours de l'année. Ils contiennent beaucoup d'informations sur la situation religieuse des XVIe au XXe siècles en Lituanie, les Églises et la vie privée du clergé.
Puisque ces éditions ont été employées comme des cahiers, on trouve ici de nombreuses notes marginales en latin, polonais, français, hébreu, grec, etc. Ces notes touchent à la vie quotidienne des prêtres, aux indications liturgiques, aux listes des prêtres décédés, aux extraits des écrits des Saints de l'Église, etc. Dans la collection, il y a à peu près 20 exemplaires avec des formules de donation.
Le contenu et la forme des calendriers liturgiques du département des livres rares de la Bibliothèque de l'Université de Vilnius sont très spécifiques, donc ils méritent plus d'attention et des recherches plus détaillées.
The personal library of the poet Jovaras
Authors: Narbutaitė Gražina
Published: August 2024

One of the popular poets, Jovaras, lived in Šiauliai. He began to collect a library in 1904 when the Lithuanian press was still banned by Tsarist Russia. He had written that there were 2,000 books in his collection. However, after his death, the collection was dispersed. Jovaras never kept an inventory of his collection. Instead, he used to write the main data about the publications in it. He used a primitive classification system. Some of the books were donated with inscriptions from his friends or the authors. Some of his books (448 items) currently belong to the "Aušra" Museum in Šiauliai. The author of the article provides a detailed analysis of the books' contents.
The life and activity of Vaclovas Biržiška in 1940 - 1945
Authors: Stakulienė Silvija
Published: August 2024

V. Biržiška's activities are noted in the archival documents that can be found in the manuscripts departments of the libraries of Vilnius University and the Academy of Sciences, as well as in the Central State Archives.
On January 1, 1940, V. Biržiška was elected the director of Vilnius University Library. At the same time, he managed the library of Vytautas the Great University. As the director of Vilnius University Library, V. Biržiška prepared new rules for readers on how to use the library, attended to the librarians' financial matters, and sought better premises. On his own initiative, on September 1, 1940, the Chair of Bibliography was established in the Faculty of Humanitarian Sciences, with V. Biržiška elected as chairman. The plan and teaching program were prepared, but World War II interrupted all his projects.
After the Germans occupied Lithuania, V. Biržiška went through a very complicated period in his life. Unable to manage the two major libraries of Lithuania, he retired from his duties as director of Vilnius University Library on November 28, 1941. He then went to Kaunas and managed the Vytautas the Great University Library.
Only a personality like V. Biržiška could manage the two greatest libraries in 1940-1941 during such a difficult period in the history of Lithuania.
Collections of books in the Samogitian County
Authors: Lūžys Sigitas
Published: August 2024

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The exposure of lead nitrate on germination and vigor processes of Helianthus (sunflower) and Lathyrus (pea) seeds
Authors:   Lviv National Environmental University, 1 Volodymyra Velykoho str., Dublyany, Lviv region, 80831, Ukraine, Khirivskyi P. R. , Korinets Yu. Ya. ,   Lviv National Environmental University, 1 Volodymyra Velykoho str., Dublyany, Lviv region, 80831, Ukraine, Mishchenko B. D. ,   Vinnytsia National Agrarian University, 3 Sonyachna str., Vinnytsya, 21008, Ukraine, Krektun B. V. ,   Lviv National Environmental University, 1 Volodymyra Velykoho str., Dublyany, Lviv region, 80831, Ukraine
Published: August 2024

It is hereby studied the exposure of lead ions on germination and growth viability of helianthus and lathyrus seeds in laboratory conditions. Certain tendencies have been revealed showing the impact of different doses of the lead ions on germination of helianthus and lathyrus as well as on the length of the root and sprout in germinating the seed. Furthermore, a particular decrease (P<0.99) in the helianthus seed germination was observed under the lead exposure at the concentration of 5×10–3 mol/L. Whereas, at the lead ions concentration in their amount from 5×10–6 mol/L to 5×10–4 mol/L, no considerable influence on helianthus and lathyrus seed germination was noticed. However, the helianthus and lathyrus root length has been exposed by the lead ions more significantly. It was noticed that the helianthus root had significantly decreased in length at the lead ions concentration of 5×10–3 mol/L, 5×10–4 mol/L, 5×10–5 mol/L and 5×10–6 mol/L (P<0.999, P<0.999, P<0.99 and P<0.999, respectively). The difference in terms of the lathyrus root length at 5×10–3 mol/L, 5×10–4 mol/L, 5×10–5 mol/L and 5×10–6 mol/L concentration of lead ions was found significant (P<0.955, P<0.99, P<0.95 and P<0.99, respectively). The study results with regard to the exposure of different doses of the lead nitrate on the average length of the helianthus sprout showed an significant difference rate (P<0.999) in these values at the lead ions concentration in the solution of 5×10–3 mol/L, 5×10–5 mol/L and 5×10–6 mol/L. There was no significant difference between the lathyrus sprout length under the lead ions exposure between 5×10–6 mol/L and 5×10–3 mol/L. Thus, as far as the research results are concerned, there has been highlighted a significant lead nitrate exposure on economically useful indicators of the helianthus and lathyrus growing. A clear tendency of the lead nitrate impact on the helianthus and lathyrus seed germination and on their root and sprout length was revealed.
Comparative analysis of different approaches for determining microbiological criteria in feed samples for animals and poultry
Authors:   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Kuriata N. V. ,   Institute of Animal Biology NAAS, 38 Vasyl Stus St., Lviv, 79034, Ukraine, Chechet O. M. ,   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Horbatyuk O. I. ,   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Pishchanskyi O. V. ,   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Musiiets I. O. ,   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Balanchuk L. V. ,   State Scientific Research Institute for Laboratory Diagnostics and Veterinary-Sanitary Examination, 30 Donetska St., Kyiv, 03151, Ukraine, Zhovnir O. M. ,   Institute of Veterinary Medicine NAAS, 30 Donetska str., Kyiv, 03151, Ukraine
Published: August 2024

The article presents research results on microbiological criteria of animal and poultry feed conducted under the requirements of the State Monitoring of Animal and Poultry Feed in accordance with the Order of the State Service of Ukraine on Food Safety and Consumer Protection for routine studies of feed samples and for in-depth studies to detect the entire species composition of microorganisms in feed samples coming from feed production enterprises in Ukraine. Isolation and identification of isolates were carried out according to current documentation. Feed is one of the main components of the food chain within the “One Health” concept to which Ukraine is committed. In-depth microbiological studies isolated from animal and poultry feed samples isolates of Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Listeria innocua, confirming high levels of contamination by pathogens indicating potential risks of their spread and danger due to possible antimicrobial resistance (AMR) and potential transmission of acquired resistance to the normal microbiota of animals and humans through feed consumption. Furthermore, animal and poultry feed are not included in the list of objects of the National Strategy of Ukraine for Containing the Development of Antimicrobial Resistance.
Az intervertebralis porckorong degenerációja és diagnosztikai megközelítése – a kvantitatív MRI által kínált lehetőségek
Authors: Schiopu Dragos , Devriendt Arnaud , Illés S. Tamás
Published: August 2024

Az ágyéki derékfájdalom világszerte a munkaképes korú populáció fogyatékosságának
egyik fő oka, jelentős költségeket róva az egészségügyi rendszerekre. A fájdalom
eredete a leggyakrabban az intervertebralis discus degenerációjára vezethető
vissza. Ennek ellenére a fájdalom eredetének meghatározása az egyik legnagyobb
kihívás a mindennapi orvosi gyakorlatban. Az intervertebralis porckorong
morfológiája pontos jellemzésének képességével a mágnesesrezonancia-képalkotás
(MRI) a leggyakrabban javallt és legfontosabb képalkotó diagnosztikai vizsgálat
a derékfájásban szenvedő betegeknél. A derékfájás okának meghatározása azonban
bonyolult. Számos különböző képi jellemző társulhat a derékfájáshoz, melyek
gyakran derékfájás nélkül is jelen lehetnek. Az elmúlt években több
MRI-szekvenciát fejlesztettek ki a deréktáji fájdalom eredetének
diagnosztizálására. Közleményünkben áttekintjük a legújabb MRI-módszereket,
amelyek képesek az intervertebralis discusok összetételében bekövetkező
biokémiai változások jellemzésére. Ezek az eljárások segítséget jelenthetnek a
discus degenerációjának és az ágyéki gerincfájdalom kapcsolatának pontos
felderítésében. Orv Hetil. 2024; 165(32): 1227–1236.
Otosclerosis
Authors: Liktor Bálint , Hirschberg Andor , Karosi Tamás , Liktor Balázs
Published: August 2024

Az otosclerosis egy máig tisztázatlan eredetű csontanyagcsere-betegség, amely
csakis humán temporalis csontban alakít ki apró csontátépüléssel járó gócokat.
Ezek az elváltozások a leggyakrabban az ovális ablakfülke elülső részén és a
stapestalpban alakulnak ki, és mechanikailag fixálják a hallócsontláncolatot,
következményes vezetéses halláscsökkenést okozva ezzel. Az otosclerosis
kezelésével kapcsolatban természetes igény, hogy különféle gyógyszeres terápiás
lehetőségekkel próbáljuk visszafordítani a betegséget, ez idáig azonban csupán a
csontátépülést sikerült lelassítani. A nátrium-fluorid- és a
biszfoszfonátkezelés igen ígéretesnek mutatkozott, súlyos mellékhatásaik miatt
azonban alkalmazásuk csak kivételes esetekben jöhet szóba. A célzott (biológiai)
terápiákhoz nagy reményt fűznek, ezeket azonban Magyarországon még nem
engedélyezték. Az otosclerosis terápiájának „gold standard” eljárása a sebészi
megoldás, mely nem a betegséget gyógyítja meg, pusztán a halláscsökkenés
vezetéses komponensét küszöböli ki. A régebbi műtéti technikát, a stapedectomiát
egyre inkább felváltja a technikailag egyszerűbb stapedotomia, ám mindmáig
szinte ekvivalens eljárásnak tekinti őket a szakirodalom. A szokványos
mikroszkópos stapessebészet mellett külön bemutatjuk a legmodernebb endoszkópos
stapedotomiát is. Orv Hetil. 2024; 165(32): 1237–1241.
Gastrointestinal disorders in secondary lactase deficiency: diagnostic features, methods of correction
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Marushko Yu.V. , Marushko T.V. ,   Shupyk National Healthcare University of Ukraine, Kyiv, Dmytryshyn O.A. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Iovitsa T.V. ,   Bogomolets National Medical University, Kyiv, Ukraine, Bovkun O.A. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: August 2024

A modern problem of practical pediatrics is secondary lactase deficiency - intolerance to dairy products containing lactose, which develops in response to a decrease in lactase activity due to enterocyte damage in an infectious, allergic, or other inflammatory process in the intestine, atrophic changes in the intestinal mucosa, and antibacterial drugs. Secondary lactase deficiency leads to flatulence, abdominal pain, and diarrhea - clinical manifestations that impair the quality of life and slow down the recovery process. An important aspect is the differential diagnosis of secondary lactase deficiency and organic and functional diseases of the gastrointestinal tract. The aim of the study is to summarize the literature data on the features of the clinical picture, diagnosis, and methods of correction of secondary lactase deficiency in children. According to the literature review, it is known that lactase deficiency can be primary or secondary and manifest clinically in both children and adults. There are various etiologic factors for the development of secondary lactase deficiency, which defines it as an urgent problem in pediatrics and a common cause of dyspeptic and abdominal syndrome in children. The clinical manifestations of secondary lactase deficiency are nonspecific and similar to the signs of organic and functional gastrointestinal diseases. The severity of the manifestations depends on the amount of lactose consumed and the level of lactase activity. Diagnostics of secondary lactase deficiency involves the use of invasive and non-invasive research methods, among which the leading role belongs to the hydrogen breathing test with a load of food lactose. Modern methods of treating secondary lactase deficiency include the administration of enzyme replacement therapy - lactase, the use of which will allow preserved breastfeeding for young children and rational nutrition for older children. The authors declare no conflict of interest.
PENYERTAAN MODAL USAHA PEMBERDAYAAN MELALUI PEMBUATAN USAHA WARUNG “PECEL, JUS, DAN ANEKA MINUMAN (MAE SARINAH)”
Authors: Nazaliah Yusma Zahrani  , Dhiyaa Azmi  , Rafa Maritza  , Ilham Mundzir
Published: August 2024

Kegiatan pengabdian masyarakat ini bertujuan untuk memberdayakan keluarga prasejahtera, khususnya berfokus pada perempuan sebagai kepala rumah tangga, melalui bantuan modal usaha. Penelitian ini menggunakan pendekatan Participatory Action Research (PAR) untuk mengidentifikasi dan membantu keluarga-keluarga yang membutuhkan di lingkungan ekonomi menengah ke bawah. Tim memilih tiga keluarga, dengan Ibu Sarinah sebagai penerima manfaat utama karena kebutuhannya yang mendesak. Ibu Sarinah, seorang juru masak yang terampil, kesulitan untuk memulai usaha karena kurangnya modal dan beban hutang. Program ini memberinya dana dan sumber daya untuk mendirikan warung kecil yang menjual "Pecel, Jus, dan Aneka Minuman" di Jakarta Timur. Prosesnya meliputi penggalangan dana, pembelian barang-barang yang diperlukan, serta pemantauan dan evaluasi berkelanjutan untuk memastikan keberhasilan dan keberlanjutan usaha. Program ini telah berhasil meningkatkan pendapatan keluarga Ibu Sarinah, yang membuktikan efektivitas inisiatif pemberdayaan. Studi kasus ini menyoroti bagaimana dukungan yang tepat sasaran dan upaya kolaboratif dapat secara signifikan meningkatkan kesejahteraan keluarga prasejahtera, sehingga mereka dapat mencapai kemandirian ekonomi dan kondisi kehidupan yang lebih baik.
BRAND PERSONALITY MATTERS: ENHANCING CUSTOMER LOYALTY IN THE RETAIL INDUSTRY
Authors: Fauziah Luluk , Subagja Agus Dedi , Anditasari Putri , Hidayat Yogi Syarif , Pujisari Yusti
Published: August 2024

Customers are an important part of a company. Therefore, customer loyalty is an important aspect that needs to be obtained by the Company. One of the steps to increase customer loyalty is through brand personality. This study aims to see how brand personality can increase customer loyalty. This research will be carried out with a descriptive qualitative approach. The data used in this study comes from various research results and previous studies. The results of this study then found that brand personality is an important factor in building customer loyalty. Through an attractive brand personality, customers will feel personally connected to the brand, where which will then increase trust and cause purchasing decisions to be more consistent.
LEVERAGING SOCIAL-MEDIA: BUILDING EXCEPTIONAL BRAND IMAGE AND BRAND AWARENESS
Authors: Mashudi Mashudi , Fatmawati Endang , Jusnita R. Ayu Erni , Gymnastiar Iman Ahmad , Indrawati Reni Sara
Published: August 2024

Penelitian ini bertujuan menyoroti signifikansi penggunaan media sosial sebagai alat dalam membangun citra merek yang kuat dan meningkatkan Kesadaran Merek. Metode literatur review digunakan secara sistematis untuk mengumpulkan, mengevaluasi, dan menyintesis temuan-temuan relevan dari berbagai sumber yang membahas pemanfaatan media sosial dalam konteks citra merek dan kesadaran merek. Hasil penelitian menjelaskan bahwa keterlibatan konten yang efektif menjadi komponen kunci dalam membangun hubungan yang kuat antara pelanggan dan merek melalui media sosial. Melalui media sosial, merek dapat memperkuat identitasnya dan membentuk hubungan emosional dengan pelanggan melalui konten yang kreatif. Pemanfaatan platform media sosial juga memungkinkan kolaborasi dengan influencer serta berbagi konten menarik, yang pada akhirnya meningkatkan kesadaran merek. hasil literatur review menekankan pentingnya citra merek yang konsisten, konten menarik, dan interaksi aktif dengan pelanggan untuk membangun kesadaran merek yang kuat dalam era digital. Merek dapat mencapai "Kesadaran Merek" dan menjalin hubungan dengan pelanggan dengan menggunakan strategi media sosial yang tepat.
BUSINESS NAVIGATION IN POLITICAL TURBULENCE: ANALYZING PRE-ELECTION ECONOMIC CONDITIONS AND ADAPTATION STRATEGIES FOR BUSINESSES
Authors: Sulastri Lilis , Supratman Iman , Sari Avid Leonardo
Published: August 2024

This literature review explores the intricate dynamics of business navigation in the face of political turbulence, with a specific focus on pre-election economic conditions and the adaptation strategies employed by businesses. The review synthesizes a range of academic sources to examine how political uncertainty, especially during election periods, influences economic environments and business operations. It delves into the various economic indicators that are typically affected by political events, such as market volatility, investment trends, and consumer confidence. The review also assesses the strategies businesses have historically adopted to mitigate risks and capitalize on opportunities during these periods of uncertainty. This includes a discussion on diversification, strategic planning, and stakeholder communication as key components of effective business adaptation. The study further explores the role of predictive analytics and scenario planning in preparing businesses for potential political outcomes and their economic repercussions. By integrating insights from various disciplines, including political science, economics, and business management, this review provides a comprehensive understanding of the challenges and strategies relevant to business decision-making in politically turbulent times. The findings highlight the importance of proactive planning and adaptability, emphasizing the need for businesses to remain agile and informed in the face of political events that can significantly impact the economic landscape.
FROM DATA TO DECISIONS LEVERAGING ADVANCED MIS FOR STRATEGIC BUSINESS INSIGHTS
Authors: Sukomardojo Tekat , Purbandono H Rahmat , Fatmawati Endang , Ratih Sri Wulan Windu , Almana La Ode
Published: August 2024

In today's rapidly evolving business landscape, Management Information Systems (MIS) play a crucial role in transforming raw data into strategic business insights. This study explores the impact of advanced MIS on decision-making processes within organizations, highlighting the integration of data analytics, business intelligence, and decision support systems. By examining various case studies and empirical data, the research illustrates how companies can leverage MIS to gain a competitive advantage, improve operational efficiency, and foster innovation. The findings suggest that the effective use of MIS not only enhances strategic planning but also facilitates real-time decision-making, thereby driving business growth and sustainability. This paper aims to provide a comprehensive understanding of the mechanisms through which MIS can be utilized to optimize business outcomes and support strategic initiatives.
Preventing Cyberbullying in Nigeria: The Effectiveness of Social Media Literacy Education for Young People
Authors: Akeusola Bolanle
Published: August 2024

The widespread integration of technology into daily life has transformed human interactions, creating unprecedented opportunities for creativity, collaboration, and communication. However, this digital evolution has also exacerbated cyberbullying, which poses significant threats to global and individual well-being. Cyberbullying is particularly prevalent among teenagers, who are active users of digital platforms and highly vulnerable to its negative impacts. In Nigeria, rapid technological advancements have heightened the incidence of cyberbullying, severely affecting the mental health, social development, and overall well-being of young people. This study aims to assess the effectiveness of social media literacy programs in reducing cyberbullying among Nigerian youth and examine how sociocultural and technological factors influence these interventions. Employing a quantitative cross-sectional design, data were collected from 480 students across three tertiary institutions in Lagos State using validated questionnaires. The findings revealed that social media literacy programs significantly reduced cyberbullying incidents. This study underscores the need for culturally sensitive and contextually appropriate interventions and highlights the importance of comprehensive strategies that address Nigeria's unique sociocultural and technological landscapes. Recommendations include the development of robust, evidence-based social media literacy programs tailored to diverse Nigerian communities, enhanced collaboration among stakeholders, and ongoing evaluations to refine and sustain these initiatives.
A Comparative Analysis of the Impact of Niger Delta Crisis on Edo and Delta States
Authors: Ehizoyanyan Oaihimire Famous , Oke Christiantus Ifeanyi Adebowale
Published: August 2024

The Niger Delta region of Nigeria has faced crises for over 40 years, resulting in high crime rates and increased insecurity of people, property, and investments. This study examines the impact of the regional crisis on the socioeconomic development and well-being of the inhabitants of Delta and Edo States. Employing quantitative research methods, including primary data collection instruments such as surveys and structured interviews, the study refined and codified the data for regression analysis. The findings reveal the detrimental effects of the Niger Delta crisis on the socioeconomic well-being of residents in both states, particularly in hindering access to essential needs such as clean water, quality education, and a healthy environment. Regression coefficients and modified coefficients of determination showed that residents of Delta State are more significantly affected by the crisis than those in Edo State. The study suggests enforcing international best practices in corporate social responsibility for oil and gas companies in the region. It also emphasizes the need for basic infrastructural development and adequate compensation and environmental remediation to achieve lasting peace and stability in the region.
Desfechos e fatores associados em pacientes submetidos ao abdome aberto após laparotomia de urgência em um Hospital Universitário no sul do Brasil: um estudo retrospectivo
Authors: SILVA ARIANA IEDA LIMA FERREIRA DA , SHEHADEH IMAD , KNAUT EDUARDO FALCO , BERTOLINO ENRICO PRAJIANTE , FONTES CARLOS EDMUNDO RODRIGUES
Published: August 2024

RESUMO Introdução: A técnica de abdome aberto refere-se a um procedimento cirúrgico que envolve deixar deliberadamente uma abertura na parede abdominal. Este estudo teve como objetivo avaliar o desfecho clínico, mortalidade e morbidade de pacientes submetidos ao abdome aberto em um hospital público do Brasil e investigar fatores de risco associados ao desfecho. Métodos: Dados a partir de prontuários eletrônicos foram coletados de 2017 a 2022. As variáveis foram utilizadas para análises descritivas, análise de associação e de sobrevivência pela curva Kaplan-Meier. Resultados: A amostra correspondeu a 104 pacientes, sendo 84 por abdome agudo e 20 por trauma, com idade e número de comorbidades variados. A peritonite e a necessidade de reabordagem precoce foram as causas mais comuns para a indicação do procedimento, 34% cada, e a terapia de pressão negativa foi a mais utilizada neste estudo, seguindo a técnica de Barker. Fístula é a complicação mais frequente (41%), sendo que a maioria se formou nos primeiros dias após a realização da cirurgia. O número de intervenções e o tempo de abdome aberto obtiveram significância estatística na comparação com o desfecho. A mortalidade geral foi de 62,5%. Conclusão: Apesar de o abdome aberto ser uma técnica que pode trazer benefícios no controle da contaminação intra-abdominal e prevenção de síndrome compartimental abdominal, sua realização está associada a complicações. A taxa de mortalidade e morbidade foram elevadas nesta amostra. A decisão para uso da técnica deve ser individualizada e baseada em vários fatores, incluindo as indicações e o estado clínico do paciente.
Literatura e resistência
Authors: Vidal Filho Antonio Fernando Longo
Published: August 2024

Resumo: Este ensaio aborda os artigos anônimos publicados por Sartre em Les Lettres Françaises, jornal clandestino editado pelo Comitê Nacional dos Escritores na França ocupada. Depois de reconstruir a circunstância histórica dessa intervenção, investiga seus fundamentos conceituais e suas matrizes literárias. No centro está uma leitura de “A Literatura, essa Liberdade!”, onde a afirmação do sentido político do ato de escrever vem circunscrita pela experiência da resistência ao nazifascismo. O percurso conduz a um balanço dos primeiros combates do engajamento.
Método Microanalítico para Investigar o Ensino de Habilidades Psicoterapêuticas e Processos Narrativo-Emocionais
Authors: Stenzel Lucia Marques
Published: August 2024

Resumo O estudo apresenta uma proposta metodológica de análise qualitativa microanalítica de sessões psicoterápicas para investigação de habilidades psicoterapêuticas na abordagem humanista-experiencial, no âmbito da formação em psicologia. Uma sessão simulada, gerada no contexto da graduação, foi analisada de forma ilustrativa. Os instrumentos aplicados por juízes externos foram o Narrative-Emotion Process Coding System 2.0 (NEPCS 2.0) e o Person-Centred & Experiential Psychotherapy Scale (PCEPS). Os resultados demonstram uma maior adesão ao modelo humanista de intervenções do tipo resposta-reflexo em detrimento de uma tomada de decisão terapêutica orientada por marcadores narrativos de processo e especificidade experiencial. Os achados ressaltam o potencial metodológico desse tipo de investigação para o aprimoramento de programas pedagógicos de ensino na perspectiva das psicoterapias baseadas em processo.
There is no well-being without oral health: a case report of Lemierre’s syndrome due to neglected odontogenic infection
Authors: Davis Edward , Kristianto Ardeno , Yang Andrew Jackson
Published: August 2024

Abstract Lemierre’s syndrome is marked by presence of septic thrombophlebitis in the internal jugular vein. This case report describes a 57-year-old woman who presented with a progressively swelling neck with onset 1 day prior to admission. She had a history of untreated dental infection. Physical examination revealed slightly increased blood pressure, at 140/80 mmHg, and a painful, erythematous, warm swelling in the mid area of the neck. Ultrasound of the neck revealed occlusive intraluminal thrombus in the right internal jugular vein, a computed tomography (CT) scan with contrast showed that there was a blockage in the right jugular vein. The mainstay treatment for Lemierre’s syndrome is antibiotics, while administration of anticoagulants remains controversial. The patient was treated conservatively, with administration of antibiotics and anticoagulant. Several days later the patient’s condition had improved significantly, with less pain and reduced swelling.
Catastrophic thrombotic events with partial bilateral amputation of legs and fingers in a 12-year-old girl with COVID-19 in Brazil: case report
Authors: Pereira Giselly Rosa Modesto , Silva André Ricardo Araújo da , Pitanga Claudia Escórcio Gurgel do Amaral , Lugon Jocemir Ronaldo
Published: August 2024

Abstract The first case of COVID-19 was detected in Dec 2019, in China. The disease shortly evolved into a pandemic and imposed an unparalleled health and social burden on mankind. Severe forms of COVID-19 mainly affect adults, especially the elderly and those with comorbidities. We report a severe case of COVID-19 in a previously healthy 12-year-old female who was admitted to the emergency room on May 26, 2020, with fever, abdominal pain, vomiting, and diarrhea. During the hospital stay, she tested positive for SARS-CoV-2 and developed multiple organ failure and catastrophic thrombotic events resulting in bilateral amputation of legs and fingers. She was discharged from the hospital for outpatient follow-up after 107 days. By the time this report was written, the patient was undergoing prosthesis prescription and training and regaining her independence to walk.
A invisibilidade das pessoas LGBT no acesso à saúde
Authors: Tesser Junior Zeno Carlos , Paim Marina Bastos , Selau Bruna Lima , Bortoli Francieli Regina , Kovaleski Douglas Francisco
Published: August 2024

Resumo Este artigo pretende problematizar a questão da invisibilidade de lésbicas, gays , bissexuais e transexuais (LGBT) e suas consequências no acesso e nas demandas em saúde dessas pessoas, tendo como pressuposto as necessidades e os problemas percebidos no movimento social que compõe os principais grupos que formam o Fórum Diversidade da Grande Florianópolis. Trata-se de uma investigação qualitativa que utilizou observação participante e entrevista. Foram realizadas nove entrevistas com lideranças do movimento LGBT da cidade de Florianópolis, Santa Catarina, Brasil. Como resultado, observou-se que as oportunidades de acesso da população ficaram circunscritas por práticas profissionais excludentes e reprodutoras de violências, baseadas em atos de discriminação social. Muitas vezes, a exposição de sexualidades e identidades de gênero não-heteronormativas podiam agravar a vulnerabilidade das pessoas. O Sistema Único de Saúde mostrou-se atravessado por constantes práticas heteronormativas que desconsideravam as vivências das diferentes sexualidades existentes entre as pessoas. Devido a isso, a população LGBT mostrou-se resistente a buscar os serviços de saúde, por considerar esses espaços como lugares em que sofrem preconceito e discriminação.
First report of harmful Microcystis sp. and microcystin in two tributaries of Paraná River in Misiones, Argentina
Authors: Kolman María de los Angeles , Miño María Laura , Kunz Isaias Emanuel , Zapata Pedro Dario
Published: August 2024

Abstract Aim Characterize cyanobacterial accumulations detected for the first time from November 2020 to February 2022 along the coastal zone of the Paraná River and in the Zaimán and Mártires streams in Posadas (Misiones, Argentina), by identifying the dominant species, determining their potential toxicity, and monitoring their progression using satellite images. Methods This work analyzes the presence of cyanobacteria by optical microscopy, the production of microcystin (MCY) by molecular and analytical methods, and the detection of these cyanobacterial accumulations by satellite image analysis. Results Optical microscopy analysis revealed the presence of Microcystis spp. colonies in all collected samples and Dolichospermum sp. in the Mártires stream. Using PCR amplification of a conserved region of the mcyE gene we confirmed the presence of MCY-encoding genes in all samples and MCY in the Zaimán stream using UPLC MS/MS analysis. Complementary satellite image analysis showed blooms in the Zaimán and Mártires streams were detectable during all the sampling periods. The presence of Microcystis spp., and MCY could affect the population, as well as the flora and fauna in the streams and the ecosystems along the Paraná River basin. Conclusions In this study, we successfully characterized cyanobacterial accumulations along the Paraná River coast and in the Zaimán and Mártires streams, revealing the presence of Microcystis spp. colonies and MCY-encoding genes, with potential implications for local populations and ecosystems.