bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of benzo (a) pyrene in Iraqi Chicken, doner kebab and fish samples cooked with charcoal or gas fire
Authors: Jasim Khalid N. , Shkhaier Samir L.
Published: January 2023

Background: Polycyclic aromatic hydrocarbons (PAHs) have been found in protein-rich food products where they are generated during certain food processing procedures. Benzo[a]pyrene (B(a)P) is a member of a class of PAHs in which the molecular structure includes two or more fused aromatic rings with adjacent rings sharing two or more carbon atoms with the formula C20H12. Dietary intake of these compounds via a formation of B(a)P on processing or cooking lead to metastasis of tumors at several sites, particularly in the upper gastrointestinal tract.Objective: We aimed to determinate B(a)P in charcoal and gas broiled chicken, doner kebab and fish meats taken from some restaurants in Baghdad.Methods: Prospective study was done in Baghdad from july to decemper 2015 in (Palestine st and alsadria). 120 samples of chicken, doner kebab and fish were collected from some resturants in Baghdad area randomly.A 20 cooked samples using a charcoal fire and gas fire for each kind of meat mentioned above to determinate B(a)P in these samples.HPLC technique was used for determination.Results: Mean levels of B(a)P were found to be (11.6±11.08 μg/kg) ,(10.0±9.4 μg/kg) and (8.4±7.8 μg/kg) for a charcoal fire broiled chicken, doner kebab and fish respectively while mean levels of B(a)P were found to be (2.5±1.9 μg/kg) ,(2.3±1.7 μg/kg) and (2.0±1.4 μg/kg) for a gas fire respectively.Conclusion: The B(a)P levels of three samples cooked on a charcoal fire exceeded the maximum tolerance level for B(a)P of the European Union establishment (2005). The highest levels of B(a)P were found in charcoal-grilled samples.Therefore,present study provides important information on B(a)P in charcoal grilled meats in Iraq. This might help to avoid the contamination in food processing to secure food safety and to protect iraqi citizens.
Assessment of early side effects of radiotherapy in breast cancer patients
Authors: Hussein Elaf A. , Al-Rawaq Khudair J.
Published: January 2023

Background: Breast cancer is the commonest cancer in women. In radiotherapy practice, it comprises 25% of patient caseload. This makes understanding the breast irradiation toxicities of prime importance. Early radiation toxicities occur during treatment and up to six months after treatment finished.Objectives: assessment of the early side effects of adjuvant external beam radiotherapy (EBRT) in breast cancer patients.Patients and Methods: A cross sectional survey with analytic component conducted on 60 patients treated in the oncology teaching hospital of medical city from January to April 2016.Results: The most prevalent toxicities were radiation dermatitis, fatigue, pain, sore throat, nausea, dysphagia, and arm edema. There was a significant difference between prevalence of dermatitis with different radiation doses used. Dermatitis was more prevalent with conventional fractionation (CF), than in hypofractionated radiotherapy.Conclusion: Dermatitis was the most common acute toxicity of radiotherapy in breast cancer patients with prevalence of 81.6 %. It was related to dose fractionation. Fatigue was the 2nd common (70%). It was correlated with disease stage.
Towards a core ontology of organisational transformation
Authors: Bogea Gomes Silvia , Santoro Flavia Maria , Mira da Silva Miguel , Pinto Paulo , Guizzardi Giancarlo
Published: January 2023

Organisations are increasingly transforming themselves to remain profitable and obtain sustainable competitive advantages. Business processes are as important as technology in promoting organisational transformation. Organisational transformation ultimately entails combining existing business components, whether or not with the same use and design, with new ones to generate novel products and services. For example, one particular type of organisation transformation is digital transformation. This notion, which covers even the subjective aspects of organisational transformation, is currently under intensive discussion and suffers from the semantics terms fluctuation related to the notion of ‘organisational transformation’. We argue that this topic could strongly benefit from an ontological analysis and conceptual clarification of these notions. This paper contributes with an attempt in this direction by proposing a Core Ontology of Organisational Transformation (COOT). This ontology comprises concepts and relations central to creating a reference model representing the organisational transformation paradigm. COOT was applied in a real-world case study on a car rental company.
Circular RNA circ_0029589 promotes ox-LDL-induced endothelial cell injury through regulating RAB22A by serving as a sponge of miR-1197
Authors: He Dequan , Li Zhiliang , Chen Youquan , Huang Ming
Published: January 2023

BACKGROUND: Dysfunction of endothelial cells is now considered a vital contributor to the pathogenesis of atherosclerosis (AS). Moreover, circular RNA (circRNA) circ_0029589 has been found to be involved in the regulation of oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell damage. Nevertheless, its molecular mechanism in ox-LDL-triggered endothelial cell injury is poorly defined. METHODS: Human umbilical vein endothelial cells (HUVECs) treated with ox-LDL were applied as cell models of AS. Circ_0029589, microRNA-1197 (miR-1197), and Ras-related protein Rab-22A (RAB22A) expression were detected using real-time quantitative polymerase chain reaction (RT-qPCR). Cell proliferation, apoptosis, angiogenesis, and invasion were detected using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-H-tetrazolium bromide (MTT), 5-ethynyl-2’-deoxyuridine (EdU), flow cytometry, tube formation, and transwell assays. Western blot analysis of Cleaved-caspase-3, B-cell lymphoma-2 related X protein (Bax), and RAB22A. IL-6, IL-1β, and Tumor necrosis factor α (TNF-α) levels were gauged using ELISA kits. Superoxide Dismutase (SOD) activity and Malondiahyde (MDA) level were assessed using special kits. Bioinformatics software predicted the binding between miR-1197 and circ_0029589 or RAB22A, which was proved using dual-luciferase reporter and RNA pull-down assays. RESULTS: Circ_0029589 and RAB22A expression were strengthened, and miR-1197 was reduced in ox-LDL-treated HUVECs. Importantly, circ_0029589 silencing ameliorated ox-LDL-triggered HUVEC damage via promoting cell proliferation, tube formation ability, invasion, and repressing cell apoptosis, inflammation, and oxidative stress. Mechanical analysis suggested that circ_0029589 might affect RAB22A content through sponging miR-1197. CONCLUSION: Circ_0090231 might protect against ox-LDL-mediated HUVEC injury via the miR-1197/RAB22A axis, which provides a therapeutic strategy for endothelial cell damage of AS.
VueBox® perfusion analysis of dynamic contrast enhanced ultrasound provides added value in the diagnosis of small thyroid nodules
Authors: Huang Yunlin , Wang Ying , Liu Lingxiao , Zhu Lei , Qiu Yijie , Zuo Dan , Lu Xiuyun , Dong Yi , Jung Ernst-Michael , Wang Wenping
Published: January 2023

OBJECTIVES: To explore the potential added value of dynamic contrast enhanced ultrasound (DCE-US) using VueBox® software for the diagnosis of small solid thyroid nodules (≤1.0 cm). PATIENTS AND METHODS: This prospective study was approved by the institutional review board and it was performed at two hospitals from January 2020 to October 2020. B mode ultrasound and contrast enhanced ultrasound (CEUS) images were obtained for 79 small solid thyroid nodules (≤1.0 cm) confirmed by ultrasound-guided fine needle aspiration cytology results in 79 consecutive patients (55 women and 24 men, median age: 41 years). The CEUS time-intensity curves (TICs) of thyroid nodules and surrounding parenchyma were created by VueBox® software (Bracco, Italy). The CEUS quantitative parameters were obtained after curve fitting. The diagnostic performance of CEUS and DCE-US was evaluated and compared. The weighted kappa statistic (κ) was performed to assess the interobserver agreement and consistency between the diagnosis of CEUS and DCE-US. RESULTS: Among the 79 thyroid nodules, 56 (70.9 %) were malignant and 23 (29.1 %) were benign lesions. Hypoenhancement during the arterial phase of CEUS was associated with malignancy (P < 0.001), with an AUC of 0.705 (sensitivity 71.4 %, specificity 69.6 %). Among all CEUS quantitative parameters, the peak enhancement (PE), wash-in rate (WiR), and wash-out rate (WoR) of DCE-US in malignancies were significantly lower than those in benign nodules (P = 0.049, P = 0.046, and P = 0.020, respectively). The area under the receiver operating characteristic curves (AUCs) of PE, WiR, and WoR were 0.642 (sensitivity 65.2 %, specificity 67.9 %), 0.643 (sensitivity 43.5 %, specificity 91.1 %), and 0.667 (sensitivity 69.6 %, specificity 69.6 %) in differentiation between benign and malignant small solid thyroid nodules (≤1.0 cm), respectively. Comparing the quantitative parameters of DCE-US between small solid thyroid nodules and surrounding normal thyroid parenchyma, the PE, WiAUC, WiR, wash-in perfusion index (WiPI), WoAUC, WiWoAUC, and WoR of the nodules were significantly lower than those of normal thyroid tissue (P = 0.008, P < 0.001, P = 0.037, P = 0.009, P = 0.003, P = 0.002, P = 0.049, respectively). A total of 16 (20.3 %) nodules showed isoenhancement during the arterial phase of CEUS, while the median PE ratio of surrounding tissue and thyroid nodules was 1.70 (IQR: 1.33–1.89). CONCLUSIONS: VueBox® is a helpful tool for the evaluation of dynamic microvascularization of thyroid nodules, and DCE-US using VueBox® perfusion analysis could provide added values for differential diagnosis of small solid thyroid nodules (≤1.0 cm).
Non-invasive evaluation of vascular architecture of focal liver lesions by micro vascular imaging
Authors: Qiu Yi-Jie , Cheng Juan , Zuo Dan , Zhang Qi , Tian Xiao-Fan , Lu Xiu-Yun , Chen Sheng , Dong Yi , Wang Wen-Ping
Published: January 2023

OBJECTIVE: To explore the value of vascular architecture detected by micro vascular imaging (MVI) in preoperative diagnosis of focal liver lesions (FLLs). METHODS: In this retrospective study, patients with surgery and histopathologically proved or radiologically confirmed FLLs were included. Vascular architecture of FLLs were acquired by color Doppler flow imaging (CDFI) and MVI on LOGIQ™ E20 ultrasound machine (C1–6 convex array probes). Alder semiquantitative analysis (grade 0–3) and morphologic features of blood vessels (pattern a–f) were used to assess the blood flow within the FLLs. Interobserver agreement for evaluating blood flow of FLLs was analyzed. Using Adler’s grading or morphologic patterns as diagnostic criteria for malignant FLLs, the diagnostic efficiency was analyzed and compared. RESULTS: From October 2021 and February 2022, 50 patients diagnosed with 40 malignant FLLs and 10 benign FLLs were finally included. The Kappa value within two observers for evaluating the blood flow of FLLs was 0.78 for MVI and 0.55 for CDFI. According to Alder semiquantitative analysis, more high-level blood flow signals (grade 2–3) were detected by MVI than CDFI (P < 0.05). Based on high-level blood flow signals (grade 2–3) and hypervascular supply patterns (pattern e and f), the diagnostic accuracy for malignant FLLs were 76% and 68% for MVI, 56% and 38% for CDFI, respectively. CONCLUSION: MVI is superior to CDFI in evaluating vascular architecture of FLLs. The high-level flow signals and hypervascular pattern detected by MVI have a useful and complementary value in preoperative non-invasive identification of malignant FLLs.
Rational and design of the REMOTE trial: An exploratory, pilot study to analyze REtinal MicrOcirculaTion in wEightlessness
Authors: Binneboessel Stephan , Masyuk Maryna , Piayda Kerstin , Bruno Raphael Romano , Wernly Bernhard , Jirak Peter , Wolff Georg , Gerdes Norbert , Baldia Philipp Heinrich , Kelm Malte , Nienhaus Fabian , Lang Alexander , Winkels Holger , Geerling Gerd , Guthoff Rainer , Kaya Sema , Flossmann Gerald , Riemer Thomas , Baertschi Michael , Jung Christian
Published: January 2023

BACKGROUND:

“Spaceflight associated neuro-ocular syndrome” (SANS) represents a challenging health condition in modern space medicine. Forty-eight percent of astronauts are diagnosed with SANS after long-term space missions. The pathophysiological mechanism seems to be multifactorial, and yet remains unknown. In this proof-of-concept study we plan to investigate retinal microcirculatory changes in weightlessness and aim to identify their role in the development of SANS.

METHODS AND DESIGN:

Healthy individuals will take part in a parabolic flight campaign, which recreates fractioned total weightlessness periods. The airplane is specifically equipped, and designed for the execution of parabolic flight maneuvers and scientific research in microgravity. Retinal microcirculation will be assessed with a modified fundus camera, which allows dynamic vessel analysis. We will additionally measure intra-ocular pressure and hemodynamic changes during each phase of the flight. Blood samples will be analyzed at baseline, one hour and 24 hours after exposure to weightlessness.

CONCLUSIONS:

This pilot study aims to investigate the feasibility of retinal microcirculation assessment during varying gravity. Results of this study may generate insights whether venous stasis in the eye, surrogated by the dilatation of retinal vessels and increase in intraocular pressure as signs of venous insufficiency, may potentially contribute to the development of SANS.
An exploration of culture and gender: Intrinsic and extrinsic job expectations in the U.S. and Brazil
Authors: Chullen Cody Logan , Barber III Dennis , Cavazotte Flavia , Adeyemi-Bello Tope
Published: January 2023

BACKGROUND: As interest in foreign business enterprises rises between the U.S. and Brazil, companies have encountered added challenges in the areas of staffing and gender inequity and inequality against the backdrop of the COVID-19 pandemic. Companies must address these challenges head on to continue to thrive. OBJECTIVE: The goal of this study is to identify and diagnose the differences in job expectations of employees in the early stages of their career and personal development in terms of their gender and nationality. METHODS: This study asked male and female workers from the U.S. and Brazil to rate the importance of various intrinsic and extrinsic job characteristics on a five-point Likert scale. Responses were compared for 1,431 total participants. RESULTS: This study found both cultural (U.S. and Brazil) and gender (male and female) differences in rank order ratings across an array of job expectations. Findings also revealed significant cultural and gender differences in mean importance scores for job expectations rated by these groups. CONCLUSIONS: This study’s findings are relevant to guide managerial practices as companies seek to attract, develop, and retain future generations of technical and managerial staff following the uncertainty brought about by COVID-19 and the Great Resignation.
Computational Evaluation of Azadirachta indica-Derived Bioactive Compounds as Potential Inhibitors of NLRP3 in the Treatment of Alzheimer’s Disease
Authors: Ishabiyi Felix Oluwasegun , Ogidi James Okwudirichukwu , Olukade Baliqis Adejoke , Amorha Chizoba Christabel , El-Sharkawy Lina Y. , Okolo Chukwuemeka Calistus , Adeniyi Titilope Mary , Atasie Nkechi Hope , Ibrahim Abdulwasiu , Balogun Toheeb Adewale
Published: January 2023

Background:

The development of therapeutic agents against Alzheimer’s disease (AD) has stalled recently. Drug candidates targeting amyloid-β (Aβ) deposition have often failed clinical trials at different stages, prompting the search for novel targets for AD therapy. The NLRP3 inflammasome is an integral part of innate immunity, contributing to neuroinflammation and AD pathophysiology. Thus, it has become a promising new target for AD therapy.

Objective:

The study sought to investigate the potential of bioactive compounds derived from Azadirachta-indica to inhibit the NLRP3 protein implicated in the pathophysiology of AD.

Methods:

Structural bioinformatics via molecular docking and density functional theory (DFT) analysis was utilized for the identification of novel NLRP3 inhibitors from A. indica bioactive compounds. The compounds were further subjected to pharmacokinetic and drug-likeness analysis. Results obtained from the compounds were compared against that of oridonin, a known NLRP3 inhibitor.

Results:

The studied compounds optimally saturated the binding site of the NLRP3 NACHT domain, forming principal interactions with the different amino acids at its binding site. The studied compounds also demonstrated better bioactivity and chemical reactivity as ascertained by DFT analysis and all the compounds except 7-desacetyl-7-benzoylazadiradione, which had two violations, conformed to Lipinski’s rule of five.

Conclusion:

In silico studies show that A. indica derived compounds have better inhibitory potential against NLRP3 and better pharmacokinetic profiles when compared with the reference ligand (oridonin). These compounds are thus proposed as novel NLRP3 inhibitors for the treatment of AD. Further wet-lab studies are needed to confirm the potency of the studied compounds.
Pseudo-random time modulation technique for neutron diffraction instruments on compact accelerator-driven neutron sources
Authors: Ott Frédéric
Published: January 2023

Time modulation methods are routinely used on neutron scattering time-of-flight instruments, which exploit the time structure of neutron pulses for energy determination. In the past, complex time modulation methods were proposed, either to maximize the neutron flux which can be used, or to increase the energy resolution of the measurements. In this article, we explore the possibilities offered by such methods and in particular random modulation using statistical choppers to improve the performances of the DIoGENE scattering instrument installed around the IPHI-neutron CANS source at Saclay. We conclude that when the source is operated in continuous mode, the implementation of a statistical chopper is very efficient to perform either metallurgical studies such as strain scanning or phase transition studies. Random modulation techniques may be easily and efficiently implemented because the high capacity of modern computers enables high-speed data processing from large surface pixelated detectors.
Practices and educational needs of Hellenic Police Officers in providing first aid/cardiopulmonary resuscitation: A cross-sectional survey
Authors: Tzenetidis Nikolaos , Kourlaba Georgia , Triantafyllou Christos , Tzenetidis Vasileios , Koulouvaris Panagiotis , Myrianthefs Pavlos
Published: January 2023

BACKGROUND: It is well known that police officers (POs) are expected to be the first responders in emergency cases requiring First Aid (FA) such as cardiac arrest. OBJECTIVE: Description of practices and educational needs of Hellenic POs in providing FA/Cardiopulmonary Resuscitation (CPR) in case of medical emergencies and description of the equipment of professional FA kit. METHODS: An anonymous cross-sectional survey was conducted from January 1, 2016, to December 31, 2017, using a self-administered questionnaire designed to serve the purposes of this particular survey. The instrument consisted of 53 questions (multiple choice and open-ended questions) administered in a convenience sample of 700 POs of the Attica prefecture. RESULTS: A sample of 520 POs (constables and lieutenants) completed the questionnaire (response rate = 74.28%). Among the participants, 248 (47.7 %) declared that they had provided FA/CPR in the past, while among those declaring that they had never provided FA/PCR (n = 248), 153 (61.7%) said that they had experienced FA/CPR needs, but did not know what they had to do. Moreover, only 18.1% (94/520) of the POs answered that they have FA equipment in their professional equipment, which mainly includes bandages (54/94, 57.4%), while 29.7% of POs provided answers about their educational needs (313 in total) declared that they would like to be educated in bleeding control. CONCLUSION: There is a need to educate and train Greek POs in first aid and CPR in an organized and mandatory way in order to meet emergency needs.
Job satisfaction in the health professions: The role of affective temperaments
Authors: Lombardo Clara , Mento Carmela , De Stefano Rosa , Infortuna Carmenrita , Iannuzzo Fiammetta , Materia Nicoletta , Muscatello Maria Rosaria Anna , Bruno Antonio
Published: January 2023

BACKGROUND: Job satisfaction, as a multidimensional psychological response to work experience, includes both cognitive and affective components which influence individuals’ appraisals and state of minds. In recent years, researchers have begun to explore the psychological processes that might underlie the dispositional causes of job satisfaction. Affective temperaments can influence the experience of emotionally significant events at work and this, in turn, may influence job satisfaction. OBJECTIVE: To investigate possible associations between affective temperamental features and job satisfaction in the health professions. METHODS: The sample consisted of 294 subjects selected among health professionals. Data were collected by an online survey including the Professional Quality of Life (ProQOL) questionnaire and the short form of the Temperament Evaluation of Memphis, Pisa, Paris and San Diego (TEMPS-A) questionnaire. RESULTS: Hyperthymic, depressive, irritable and anxious temperaments predicted the risk of experiencing job dissatisfaction in healthcare professionals. No associations between cyclothymic temperament and job satisfaction were found. CONCLUSION: The identification of affective temperamental assets and liabilities is potentially useful in the development of supportive and psycho-educational strategies, aimed at preventing work-related stress and promoting mental health in workplaces, also reducing the risk of job dissatisfaction.
Super-resolution image reconstruction from sparsity regularization and deep residual-learned priors
Authors: Zhong Xinyi , Liang Ningning , Cai Ailong , Yu Xiaohuan , Li Lei , Yan Bin
Published: January 2023

BACKGROUND:

Computed tomography (CT) plays an important role in the field of non-destructive testing. However, conventional CT images often have blurred edge and unclear texture, which is not conducive to the follow-up medical diagnosis and industrial testing work.

OBJECTIVE:

This study aims to generate high-resolution CT images using a new CT super-resolution reconstruction method combining with the sparsity regularization and deep learning prior.

METHODS:

The new method reconstructs CT images through a reconstruction model incorporating image gradient L0-norm minimization and deep image priors using a plug-and-play super-resolution framework. The deep learning priors are learned from a deep residual network and then plugged into the proposed new framework, and alternating direction method of multipliers is utilized to optimize the iterative solution of the model.

RESULTS:

The simulation data analysis results show that the new method improves the signal-to-noise ratio (PSNR) by 7% and the modulation transfer function (MTF) curves show that the value of MTF50 increases by 0.02 factors compared with the result of deep plug-and-play super-resolution. Additionally, the real CT image data analysis results show that the new method improves the PSNR by 5.1% and MTF50 by 0.11 factors.

CONCLUSION:

Both simulation and real data experiments prove that the proposed new CT super-resolution method using deep learning priors can reconstruct CT images with lower noise and better detail recovery. This method is flexible, effective and extensive for low-resolution CT image super-resolution.
Pharmacoeconomic aspects of hospital treatment of facial fractures - cost of illness study based on data from Balkan country with recent history of social and economic transition
Authors: Desnica Jana , Kostić Marina , Janković Slobodan , Mijailović Sara , Parezanović Ilić Katarina , Milovanović Olivera , Vulović Dejan
Published: January 2023

Background/purpose: The incidence of facial fractures has a tendency to rise, which positively correlates with increasing total costs of treating this medical condition. The aim of this study was to identify the total costs of the hospital treatment of facial fractures and to analyze its main determinants.
Materials and methods: This retrospective "cost-of-illness" study "from bottom to the top" approach was performed from the perspective of the Republic Health Insurance Fund. This study included 46 patients who were treated due to facial fractures at the Clinic for Maxillofacial Surgery at the Clinical Center Kragujevac in the period from the beginning of December 2017. to January 31, 2019.
Results: The total costs of hospital treatment of all types of treated fractures amounted to 20,214.30€, and the average total cost per patient was estimated at 439.44±299.53€. The costs related to the length of hospitalization represented the largest part of the total direct costs, with a contribution of 31% and with a value of 6,329.30±80.18 €.
Conclusions: Results of this pilot study pointed out that the total costs of treating facial fractures in the socio-economic sphere of Balkan countries are lower than in other health care systems, mostly due to differences in valuing medical services compared to countries within the European Union. Due to the rising incidence of injuries and obligatory hospital treatment of these conditions, this kind of pharmacoeconomic evaluation could contribute to the introduction of new therapeutic strategies for adequate allocation of resources within health systems.
The importance of using inflammatory biomarkers and scoring systems in early assessment of severity and outcome of acute pancreatitis treatment
Authors: Marinkovic Olivera , Trpkovic Sladjana , Sekulic Ana , Ilic Aleksandra , Pavlovic Aleksandar , Loboda Barbara , Grbovic Vesna , Todorovic Zeljko , Simovic Stefan , Zdravkovic Natasa
Published: January 2023

Acute pancreatitis (AP) is an inflammatory disease of the pancreas that causes local damage and systemic inflammatory response. Some of the numerical scoring systems used in the intensive care unit for the assessment of critically ill patients such as APACHE II and MEWS score could be used for AP, beside the scoring systems specific to AP (Ranson score, Pancreas score, BISAP). Therefore, the aim of this study was to examine the significance of inflammatory biomarkers and scoring systems in the evaluation of the severity of AP and outcomes.
The study was conducted as a cohort prospective study, examining patients with AP, of both sexes. Laboratory analyses, as well as the scoring systems: Ranson, Pancreas score, Bedside Index of Severity in Acute Pancreatitis (BISAP), and Acute Physiology and Chronic Health Evaluation II (APACHE II) were collected on day zero and 48h after admission.
The study included 50 patients of whom 8 died. The most reliable score for predicting AP severity was APACHE II0 and 48AUROC (0.753; 0.768) in relation to the inflammatory biomarkers. For initial prediction of the treatment outcome, APACHE II0, BISAP0, and CRP0 AUROC (0.813; 0.807; 0.753) had the highest discrimination rates and after 48h, APACHE II48, Ranson48, BISAP48, and Pancreas48 AUROC (0.917; 0.856; 0.789; 0.729). There was a statistically significant correlation between CRP0 and BISAP0 (p=0.006) and between PCT and all day-zero scores.
All tested screening systems showed reliability in predicting AP severity and treatment outcomes. The best predictive power was demonstrated by the APACHE II score.
UPAYA KPP PRATAMA MAGELANG UNTUK MENINGKATKAN KEPATUHAN WAJIB PAJAK ORANG PRIBADI DALAM PELAPORAN SPT TAHUNAN PAJAK PENGHASILAN TAHUN PAJAK 2015-2019
Authors: Setyawan Erwin Budi
Published: January 2023

Penelitian ini membahas tentang bagaimana tingkat kepatuhan wajib pajak orang Pribadi dalam pelaporan SPT Tahunan Pajak Penghasilan di Kantor Pelayanan Pajak Pratama Magelang dimana dari hasil penelitian yang dilakukan diperoleh hasil bahwa tingkat kepatuhan wajib pajak orang pribadi dalam pelaporan SPT tahunan mengalami peningkatan dan penurunan yang fluktuatif. Pada di tahun 2015 tingkat kepatuhannya turun menjadi 45,60% masih ditingkat “rendah” karena dari 79,383 Wajib Pajak Orang Pribadi, yang lapor tepat waktu hanya 36,205 Wajib Pajak saja. Kemudian tahun 2016 terjadi peningkatan kepatuhan cukup tinggi dibanding tahun-tahun sebelumnya dan mencapai tingkat “tinggi”, walaupun jumlah Wajib Pajak terdaftar yang wajib lapor SPT mengalami penurunan dibanding tahun sebelumnya. Pada tahun 2016 tingkat kepatuhannya mencapai 79,39%, dimana terdapat 45,637 Wajib Pajak yang lapor tepat waktu dari 57,484 Wajib Pajak terdaftar wajib SPT . Selanjutnya, pada tahun 2017 terjadi penambahan jumlah Wajib Pajak terdaftar Wajib SPT dibanding tahun 2016, yaitu berjumlah 70,075 Wajib Pajak. Namun, pada tahun 2017 tingkat kepatuhannnya mengalami penurunan pada tingkat 58,64% saja dan berada pada tingkat “Sedang” karena dari 70,075 Wajib Pajak terdaftar wajib SPT, hanya 41,090 Wajib Pajak saja yang lapor tepat waktu. Pada tahun 2018 terjadi peningkatan kepatuhan sebesar 1,86% dari tahun 2017, yaitu sebesar 60,50%. Terdapat 56,533 Wajib Pajak terdaftar wajib SPT dan yang lapor tepat waktu sejumlah 34,203 Wajib Pajak dan berada pada tingkat “Sedang”. Kemudian pada tahun 2019 terjadi peningkatan kembali pada jumlah wajib pajak orang pribadi yang terdaftar wajib SPT menjadi 60,735 kenaikannya sebesar 4,202. Dengan jumlah wajib pajak orang pribadi yang melakukan pelaporan SPT tepat waktu adalah 60,231 dengan yang mengakibatkan presentasenya menjadi 79,43% dengan kriteria tinggi. Selanjutnya, jika dirata-rata tingkat kepatuhan Wajib Pajak Orang Pribadi dalam pelaporan SPT Tahunan pajak penghasilan tahun pajak 2015-2019, tingkat kepatuhannya adalah 64,58%. Upaya yang dilakukan KPP Pratama Magelang untuk meningkatkan jumlah pelaporan STP wajib Orang Pribadi pajak Penghasilan Tahun 2015-2019 adalah dengan membuat program-program dalam rangka meningkatkan jumlah pelaporan SPT tahuan tersebut adapun program yang dilaksanakan adalah sebagai berikut : Melaksanakan program penyuluhan rutin (sit in), Penyuluhan secara personal kepada Wajib Pajak oleh AR (Account Representative) di KPP Pratama Magelang, Penyuluhan kepada Wajib Pajak baru oleh Seksi Ekstensifikasi melalui “Kelas Pajak”.
UPAYA MENINGKATKAN DISIPLIN KERJA KARYAWAN PT. SMART TALENTA MULTITAMA MELALUI FUNGSI PENGAWASAN
Authors: Effendhi Lukman , Sutrischastini Ary
Published: January 2023

The aims of this study are 1) to identify the causes of employee discipline at PT. Smart Talenta Multitama is not yet optimal and 2) determines efforts to improve the work discipline of employees of PT. Smart Talenta Multitama through the supervisory function. This research is a qualitative research. Data collection techniques were carried out using a questionnaire. The number of samples is 13 employees with purposive sampling method. Data analysis consists of three paths, namely data reduction, data presentation and drawing conclusions.The results showed that 1) the causes of work discipline at PT. Smart Talenta Multitama has not been maximized, namely low absenteeism, accuracy in entering and leaving work and adherence to regulations. This can be seen from the average value of the three indicators of 2.19 which is in the unfavorable category. 2) Efforts to increase supervision to improve the work discipline of employees of PT. Smart Talenta Multitama are: a) The frequency of supervision must be increased so that the employee's work does not deviate from the established provisions;b) The supervision carried out should pay attention to attendance, the accuracy of entering and leaving work for employees, and compliance with regulations so that employee work discipline increases; and c) Leaders should reward disciplined employees and punish employees who do not follow the rules or are not disciplined.
PENGARUH GAYA KEPEMIMPINAN MELAYANI DAN BEBAN KERJA TERHADAP KEPUASAN KERJA PEGAWAI DI KECAMATAN MAGELANG UTARA KOTA MAGELANG DENGAN MOTIVASI KERJA SEBAGAI VARIABEL INTERVENING
Authors: Widiastuti Nur , Riauwanto Selamat , Harwati Christina Anik
Published: January 2023

Penelitian ini bertujuan untuk menganalisis pengaruh dan hubungan antara 4 (empat) variabel yaitu variabel gaya kepemimpinan melayani, beban kerja, motivasi kerja dan kepuasan kerja serta menguji variabel intervening sebagai variabel mediasi antara variabel bebas dengan variabel terikat. Jenis penelitian ini adalah penelitian kuantitatif. Penelitian ini dilakukan di Kantor Kecamatan Magelang Utara menggunakan metode korelasional. Pengambilan sampel menggunakan metode nonprobably sampling dengan teknik sampling jenuh. Responden sebanyak 104 responden. Data yang diperoleh dengan menyebarkan kuesioner kemudian dianalisa dengan menggunakan uji regresi linear berganda dan uji hipotesis dengan menggunakan SPSS IBM versi 22. Hasil penelitian ini menunjukkan bahwa hipotesis yang diterima adalah hubungan positif dan signifikan antara ketiga variabel bebas terhadap variabel terikat. Sedangkan pada hubungan gaya kepemimpinan melayani terhadap kepuasan kerja, variabel motivasi kerja tidak dapat menjadi variabel mediasi, yang berarti bahwa motivasi kerja tidak dapat sebagai variabel intervening, namun pada hubungan pengaruh beban kerja terhadap kepuasan kerja, motivasi kerja dapat menjadi variabel intervening.
TELAAH ADAB PENUNTUT ILMU DALAM ḤILYATU ṬĀLIB AL-‘ILMI DAN IMPLIKASINYA TERHADAP PEMBELAJARAN PAI
Authors: Hamdi Miftahul , Syahidin Syahidin , Firmansyah Mokh Iman
Published: January 2023

Adab is an ornament for a student of knowledge, a student of knowledge who has studied PAI (Islamic Religious Education) which in its sub-material contains material related to adab, has good manners towards himself, his teacher and friends and the surrounding environment, in fact PAI learning should be able to make a student of knowledge have good manners on the contrary, such as the occurrence of a very worrying phenomenon such as the crisis of adab from students of knowledge both to their teachers and friends, one of the cases is how dare a student of knowledge disobey his teacher which occurred in Yogyakarta on February 22 2019 in this case, a student of knowledge dared to fight his teacher because his cellphone was confiscated by his teacher, due to this phenomenon the functions and results of PAI learning can be said to be unsuccessful. The purpose of this study is to describe the adab of a knowledge in the book student of Ḥilyatu Ṭālib Al-‘Ilmi by Shaykh Bakr bin Abdullah Abu Zaid and its implications for PAI learning which is expected to be a solution in an effort to improve the quality of education and form students who have manners in accordance with the Law System. National Education (SISDIKNAS) no. 20 of 2003 which one of the goals is to make humans have noble character. This study uses a qualitative approach to the method of library research (library research). Researchers are the key instrument in research, collecting data using techniques library research. Research data analysis was carried out in the form of data reduction, data presentation/display, and data conclusion/verification. The results of the study show that the adab of theknowledge in the book of student of Ḥilyatu Ṭālib Al-‘Ilmi has implications for PAI learning, especially the material on adab for a student of knowledge.
MODERASI BERAGAMA: URGENSI DAN KONDISI KEBERAGAMAAN DI INDONESIA
Authors: Hikmah Afroh Nailil , Chudzaifah Ibnu
Published: January 2023

Cultural diversity (multicultural) is a natural event due to the meeting of various cultures, the interaction of various individuals and groups carrying cultural behavior, having different and specific ways of life. Diversities such as cultural diversity, family background, religion, and ethnicity interact with each other in the Indonesian community. In horizontal communication between communities, Mulyana said, clashes between tribes are still taking place in various areas, ranging from stereotypes and prejudices between tribes, discrimination, to open conflicts and massacres between tribes that take lives. Competition between tribes is not only in the community but also among political elites and even academics to occupy positions in various agencies. This study aims to explain the importance of being moderate in religion and also to see how the conditions of religion in Indonesia are through descriptive qualitative research. The results of this study are 1) Moderation of religion as an effort to always maintain that whatever variety of interpretations and understandings of religion are maintained according to the corridor so as not to bring up extreme religious ways. Because the main points of religious teachings are basically the same, such as humanity, justice, equality before the law, respect for human rights and other universal values. 2) Based on research conducted by the Ministry of Religion, it shows that the 2021 Religious Harmony Index (KUB) is in the good category. Its value is at the national average of 72.39, up 4.93 points from the previous year.
Pengaruh Pembelajaran Pendidikan Agama Islam Terhadap Peningkatan Jiwa Nasionalisme
Authors: Satir Muhammad , Yunita Dina Suci
Published: January 2023

This study aims to determine the influence of Islamic Religious Education learning on increasing the nationalism of students at SMP Negeri 26 Sorong Regency and the significant influence of Islamic Religious Education learning on increasing the nationalism spirit of students at SMP Negeri 26 Sorong Regency.This research uses Quantitative research with an Associative quantitative approach—the population of all Muslim students from classes VII-IX. The sample collection was carried out thoroughly by conducting a population study of 38 students. Data collection was carried out by distributing questionnaires and analyzed using simple regression tests, T (Partial) tests, and coefficient of determination tests.The results of this study show that: First, Learning Islamic Religious Education affects the improvement of the nationalistic spirit of students at SMP Negeri 26, Sorong Regency. This can be seen from the results of a simple regression test with the equation Y = 31,888 + .727 + e with a constant value is 31,888, and the value of the regression coefficient of Islamic religious education learning is 0.727. Second, there is a significant relationship between learning Islamic religious education and increasing the nationalism of students at SMP Negeri 26 Sorong Regency by 0.599. This can be seen from the results of the T-Test. It was obtained at 4,488. It is known that the T-Table with a significance level of 0.05 with df = n-k = 36, then the magnitude is 2.02619. The value of the coefficient of determination is found in the Adjusted R Square value of 0.341. This means that the ability of free variables to explain bound variables is 34.1%, while other variables influence 65.9%. Therefore, the results are significant, and the proposed hypothesis is acceptable.
Integrasi Nilai-Nilai Pendidikan Agama Islam dalam Tradisi Pembacaan Ratib Al-Haddad
Authors: Septian Rahmat Yudhi , Wanto Deri
Published: January 2023

There is a community tradition in the village of Suka Datang, which is the Ratib Al-Haddad which is a collection of readings in Arabic in the form of zikr and supplication that has traditionally been read at every feast in a family that is in the midst of death. This research aims to find out the implementation of the Ratib Al-Haddad and the values ​​of Islamic religious education found in it. This research uses the ethnographic qualitative approach, which is research that emphasizes a culture from the behavior patterns, habits and way of life of the community. The results of the research show that the implementation of Ratib Al-Haddad is carried out at night exactly after the Maghrib prayer, when there is a calamity of death usually Ratib Al-Haddad will be practiced for 3 or 7 nights in a row at the residence of the victim. This Islamic nuanced tradition has been done by the Suka Datang village community since 1975 AD. In the tradition of Ratib Al-Haddad in the village of Suka Datang, there are values ​​of Islamic religious education, namely the values ​​of belief, worship, morals and muamalah. Uniquely, there is also a component of Islamic religious education in this prediction of Ratib Al-Haddad, such as; educators, students, educational environment, learning materials and learning methods.
Development of a continuous operation hop-kiln with power supply
Authors: Prosviryakova M. V. , Goryacheva N. G. , Storchevoy V. F. , Mikhailova O. V. , Novikova G. V. , Kirillov N. K.
Published: January 2023

Introduction.Hop production in the Russian Federation averages 116 thousand tons from 54 thousand hectares. The HS-400 hop-kiln used in the hop drying process line is energy-intensive. The concept of hop growing development in the Chuvash Republic for 2020–2025, approved by the decree of the Cabinet of Ministers of the Chuvash Republic (dated 20.08.2020 No. 738-r), provides for the development of up to 45–50 hectares of new areas for hop, at the rate of 15–17 hectares per one hop-kiln HS-400. To expand the production of hop, it is necessary to effectively master innovative technologies and installations for drying freshly harvested hop that are not inferior in technical and economic parameters of foreign analogues. The development of a hop-kiln that provides dehydration and disinfection of freshly harvested hop, pre-servs consumer properties with reduced operating costs, is currently relevant.Methodology.The electrophysical parameters of hop cones (according to the Rogov method) were analyzed depending on the frequency of the electromagnetic field, humidity and temperature, heat and mass transfer processes during the supply of convective heat to the volumetric resonator of the microwave installation were theoretically investigated, and the effective technological parameters of the hop-kiln were determined. Studies of the electromagnetic field strength, current density, and intrinsic Q-factor of resonators were carried out in the CST Studio Suite 2017 three-dimensional computer modeling program and its CST Microwave Studio subprogram.Results.A multi-resonator hop-kiln with an energy supply in an electromagnetic field has been developed. The proposed hop-kiln contains resonators sequentially arranged in a horizontal plane with curved surfaces, docked through ceramic biconvex perforated plates. The design and technological scheme of the hop-kiln has been developed. The intrinsic Q-factor of elliptical toroidal resonator is 14600, of triangular prismatic resonator — in the range of 9000–1200, depending on the degree of concavity of the upper face. The calculation of the installation productivity amounts to 180–200 kg/h with a power of 15.66 kW, which made it possible to determine energy costs — to 0.1 kWh/kg.
New methodological approach to calculations for design of energy-saving device for heating water intended for livestock watering
Authors: Dulepova Yu. M. , Dulepov D. E. , Alexandrova A. A. , Samarin G. N. , Mardaryev S. N.
Published: January 2023

Relevance. The development and use of new tools and technologies aimed at energy saving in agriculture has been and remains an urgent task. The use of non-traditional and renewable energy sources has become very popular. An advanced role in this direction is acquired by the use of heat released by cattle.Methods. It is assumed that due to the free heat, which is directed to the disposal of the livestock premises, heating will occur, for which a new device for heating water has been developed. Based on the results of calculations and observations, it was decided that the device for water heating will be placed in the place where the air temperature in the livestock premises reaches maximum values. There are a number of issues that need to be solved. One of them is an important part of the design of a new heating device — this is the calculation of its constructive parameters.Results. It is necessary to take into account many factors that affect the heat generation of cows, their drinking conditions, possibility of the installation of the heat exchanger to affect the ventilation in premises, its heating capacity. The calculation of these parameters will make it possible to evaluate in real conditions of use of water heating device, working due to the release of heat from cattle. Its use will reduce the consumption of electric energy, which is used to heat water intended for cows.
Study of permutation decoding algorithms in UAV control systems
Authors: Sorokin I. A. , Romanov P. N. , Kondranenkova T. E. , Ruzhev V. A. , Stenina N. A. , Pushkarenko N. N.
Published: January 2023

Relevance. This paper presents relevant topic of the use of unmanned aerial vehicles (UAV) in the agroindustrial complex (AIC) to obtain timely reliable information about the state of agricultural land for the entire period. In modern infocommunication technologies and communication systems, high requirements are placed on the reliability of information transmission. In mobile data exchange systems, compositions of noise-resistant codes are used in the form of cascade designs or turbo codes, and in order to increase their efficiency, it is necessary to make the fullest use of the redundancy introduced at each stage of data processing. To solve such a problem, it is advisable to apply a decoding method based on the ordering of the character confidence indices (CCI) of the code combination.Methods. When determining the encoding-decoding systems, the Mathcad application software was used. Mathematical studies have shown that binary block codes for reaching the specified boundary can be decoded not only on the basis of ordered statistics, but also using the method of dividing the space of allowed code combinations into clusters. Based on this method, a block diagram of the algorithm of the simulation model of the operation of the block code decoder based on cluster calculation is compiled.Results. The application of the proposed method of soft decoding of systematic block codes reduces the processing time of code combinations in the decoder by reducing the dimension of the square matrix to determine the nonlinearity property of the rows of the rearranged generating matrix after ordering the columns of the original generating matrix.