bluuebunny/crossref_metadata_2025 huggingface dataset:
ADAPTACIÓN CULTURAL Y ANÁLISIS PSICOMÉTRICO DE UNA ESCALA DE COMPORTAMIENTOS DE AUTOCUIDADO EN PERSONAS CON INSUFICIENCIA CARDÍACA
Authors: Gonzalez Madrid Marcela , Pedrero Castillo Victor , Guardamagna Molinos Carmen Luz , Saavedra Maino Charlotte , Ferrer Lagunas Lilian , Verdejo Pinochet Hugo
Published: December 2023

INTRODUCCIÓN: La Insuficiencia Cardiaca se ha descrito como un síndrome de proporciones epidémicas, con una prevalencia de un 1-3% de la población adulta mundial menor de 60 años. Las conductas de autocuidado constituyen una estrategia clave en la elaboración de intervenciones exitosas que disminuyan la re-hospitalización, mortalidad y mejoren la calidad de vida. OBJETIVO: Adaptar y validar la Escala Revisada de Comportamientos de Autocuidado en Falla Cardiaca (Revised Heart Failure Self Care Behavior Scale) en personas con insuficiencia cardíaca, que se encuentran en seguimiento ambulatorio, en dos Hospitales Públicos chilenos. METODOLOGÍA: Estudio transversal de adaptación y análisis psicométrico del instrumento de medición Escala de Valoración de Comportamientos de Autocuidado en personas con Insuficiencia Cardíaca diseñada por Nancy Artinian. Emplazamiento: Unidades ambulatorias de seguimiento en Hospitales Públicos chilenos. Participantes: Usuarios con Insuficiencia Cardíaca que asistieron a dos Policlínicos de seguimiento de Insuficiencia Cardiaca de dos Centros de Salud de nivel secundario de dos comunas de Santiago en Chile. Método: Se realizó juicio de expertos para la adaptación cultural del instrumento, se aplicó el análisis factorial exploratorio con rotación oblicua. RESULTADOS: Escala Chilena de Valoración Comportamientos de Automanejo en Insuficiencia Cardiaca presentó una adecuada adaptación cultural, pruebas sicométricas que garantizan su validez de constructo y fiabilidad adecuada, con Alfa de Cronbach del Instrumento de 0,84 IC [0,80-0,88]. CONCLUSIONES: Se proporciona un instrumento que permite conocer conductas de autocuidado de los pacientes con IC, esto le permite ser utilizado por los profesionales que atienden a personas que padecen de IC en Chile.
Experiencia de Dios y Ecosistema. Acercamiento a la fundamentación filosófica teológica desde la obra Ser finito y Ser eterno. Ensayo de una ascensión al sentido del Ser de Edith Stein
Authors: Meis Anneliese
Published: December 2023

La presente exposición no cuenta con un conocimiento específico del ecosistema. Ella se basa en un saber general de esta temática, avalado por una revisión de la literatura más reciente y un estudio detenido de la Laudato Si. La delimitación básica, enriquecida y cambiada por diversas perspectivas de accesos múltiples en el transcurso del tiempo, orienta el acceso de la presente conferencia desde la “filosofía del ser” de Edith Stein como un “esbozo de una doctrina del ser” , basada en la experiencia originaria configurada a modo de una sinfonía, gracias a la interrelación abierta de la filosofía con la teología y viceversa. Parte de la “base de la experiencia originaria”y su certeza simple del ser para dilucidar en el espíritu humano “la relación recíproca de la conciencia y del mundo objetivo” acercándose así al origen último del ecosistema, Dios Trino y Uno.
Spatial Assessment and Variation of Soil Physicochemical Properties and Water Quality in the Tungi Watershed of Maharashtra, India
Authors: Shrivastav Akshay , Vaidya P. H.  , Thale L. R.
Published: December 2023

Aims: To thoroughly evaluate the spatial variability of soil physicochemical properties and groundwater quality of the study area by systematic collection and analysis of geo-referenced soil and groundwater samples to quantify the physical, chemical and biological attributes of the soil. The objective is to gain a comprehensive understanding of soil and water quality in the Tungi watershed, providing valuable insights to guide sustainable land and water management practices in the region.

Place and Duration of Study: Department of Soil Science and Agricultural Chemistry, College of Agriculture, Latur between 2020 and 2021.

Methodology: A total of one hundred geo-referenced surface soil samples (0-30 cm) and ten groundwater samples were methodically collected from the surrounding area of soil profiles in the Tungi watershed, situated in Latur, Maharashtra. Physical, chemical and biological properties of soil evaluated using recommended standard methods.

Results: Bulk density varied from 1.13 to 1.93 Mg m-3, particle density from 2.48 to 2.94 Mg m-3 and porosity from 22 to 58 percent. Soil pH ranged from 7.05 to 8.96 and electrical conductivity was within the permissible range. Organic carbon content of soils ranged from 0.15 to 1.05 percent, with some soils having a calcareous character (0.6 to 22.2 percent). The analysis of nutrient content revealed variable quantities with available nitrogen ranging from 53.31 to 250.88 kg ha-1, available phosphorus from 12.51 to 27.49 kg ha-1, available potassium from 106.9 to 851.5 kg ha-1 and available sulphur from 4.37 to 66.65 mg kg-1. Exchangeable calcium and magnesium quantities revealed ranges of 14.60 to 42.40 cmol(p+) kg-1 and 5.40 to 21.60 cmol(p+) kg-1, respectively. Furthermore, DTPA extractable iron varied from 4.24 to 16.38 mg kg-1, manganese from 4.76 to 25.84 mg kg-1, zinc and copper from 0.5 to 6.56 mg kg-1 and 0.72 to 15.56 mg kg-1, respectively and boron from 0.1 to 3.56 mg kg-1. Microbial population estimates revealed the dominance of bacteria over fungi and actinomycetes in the studied area. Groundwater carbonate and bicarbonate ranged from 0.01 to 0.62 m mol-1 and 6.35 to 10.24 mmol-1 respectively. The dug well, bore well and tube well water RSC ranged from 0.70 to 1.25 mmol-1.

Conclusion: This extensive study provides helpful insights into the regional variability of physical and chemical properties in both soil and water with help of soil fertility maps, providing better understanding of soil fertilizer input and environmental conditions in the Tungi watershed.
Understanding the Association between Selected Agama agama Characteristics and Intestinal Parasitic Infection in Otuoke, Nigeria
Authors: Ezenwaka Chinonye Oluchi
Published: December 2023

Lizards (Agama agama) are the most widely distributed reptiles and has shown to be a means of transport and reservoir host to a number of protozoan and helminth parasites. The aim of this study is to determine the association between parasitic infection of Agama agama and selected characteristics (age and sex). The observational study was carried out at Otuoke community where 50 Agama agama comprising both male and females were randomly obtained. The lizards were sacrificed and their feaces were collected from their intestines and studied in the laboratory for parasite presence using light microscope. The results showed the identification of four parasites in the lizards namely; nematode (Strongyluris brevicaudata and Parapharyngodon colonensis), cestode (Oochoristica truncate), trematode (Mesocoelium monas) and Conoidasida (Toxoplasma gondii). There was no association between age (described as length of the animal) and prevalence of parasitic infection. Also, there was no association between sex and prevalence of the parasitic infection and finally, there was no association between weight and prevalence of the parasitic infection. This study has shown that although parasites are present in Agama agama, there was no gender, age and weight variations or dependence of the rate of their infection.
Implementation of Servant Leadership at “X” Christian High School in Surabaya
Authors: Pujiastutianingsih Kristina , Ricky Ricky
Published: December 2023

Servant leadership is a leadership approach that requires leaders to understand and meet their followers’ needs. During the pandemic, the learning process occurred remotely, requiring educational leadership that understands the difficulties faced by both teachers and students. This study examines how leaders and teachers understand and implement servant leadership in the learning process through a consultative project involving leaders, teachers, and students through interviews and questionnaires. The author used the Servant Leadership Behaviour Scale (SLBS) as a theoretical basis and statement items for 246 students. This research used ’mixed methods’ by combining qualitative and quantitative data. The author found the understanding of Servant Leadership in the leaders and teachers, including listening, serving by example, empathising, and cooperating to achieve common goals. Then, its application included listening, serving what’s needed, building relationships, inviting followers to think about the organisation, sparing time, paying attention to spirituality and morality, accepting criticism, and admitting mistakes. The SLBS dimensions found from those understanding are Voluntary Subordination, Covenantal Relationship, and Transforming Influence. The SLBS dimensions found from the application are Voluntary Subordination, Covenantal Relationship, Transforming Influence, Transcendence Spirituality, and Authentic Self.
Enhancing Customer E-Loyalty and E-WOM: The Role of Electronic and Non-Electronic Service Quality and Customer Satisfaction (PLN Mobile Application)
Authors: Lesmana Aji , Balqiah Tengku Ezni
Published: December 2023

This study examines the relationships between six constructs: e-service quality, customer e-satisfaction service quality, customer satisfaction, customer e-loyalty, and electronic word-of-mouth (EWOM). The study collected data from 452 respondents who are customers of PLN and have used the PLN Mobile application. The study found that customer e-loyalty can be directly and indirectly influenced by service and e-service quality. Both customer satisfaction and e-satisfaction can mediate the influence of service quality and e-service quality on customer e-loyalty. Therefore, PLN needs to ensure service quality (both through the application and field personnel) and customer satisfaction with the services provided to enhance customer satisfaction and foster electronic loyalty, encouraging customers to continue using the PLN Mobile application. The study also reveals that customer e-loyalty positively and significantly influences EWOM.
Exploring Hospital Supply Chain Partnership Factors and Its Impact on Overall Supply Chain Performance
Authors: Setiawati Marla , Pasaribu Aiko , Halim David Prasetya , Darmawan Juan
Published: December 2023

Hospitals function as complex businesses with intricate supply chain networks involving collaboration among various entities to efficiently deliver information, goods, and services to end customers. This study investigates the causal relationships between hospitals, suppliers, and government entities within the supply chain network. Employing system thinking, system dynamics, and causal-loop diagrams, it assesses how coordination, collaboration, and integration impact hospital supply chain performance. The findings reveal that high coordination and collaboration among suppliers, hospitals, and government entities positively influences supply chain performance. The study identifies key factors contributing to effective partnerships, such as information sharing, trust levels, supplier quality standards, inventory capabilities, flexibility, pricing strategies, and IT integration. Additionally, the research considers hospitals' dynamic capabilities, key performance results, patient outcomes, government healthcare spending, regulations, and economic indicators. Managerial implications emphasize the importance of strong partnerships to enhance overall supply chain performance, potentially improving patient outcomes and healthcare service quality. While acknowledging limitations, the study suggests future research avenues, including exploring the impact of other stakeholders and specific factors on hospital supply chain management.
Reviewing 2023: Overdoses, medications, harm reduction, and more challenges for SUD treatment providers
Authors: Knopf Alison
Published: December 2023

As always, ADAW's Preview issue includes this review of stories in 2023. We couldn't include everything but did focus on the areas that required in‐depth reporting, including methadone reform, which is a moving and controversial target. Click on the links for the abstracts. Subscribers can read full articles.
In Situ Reinforced Heterocyclic Aramid Fiber with Nanosized Graphene Whiskers: Small Addition, Big Gains
Authors: Xiao Zhihua , Sun Yankun , Li Zechen , Zheng Fangzhi , Zhao Lu , Sun Dong , Zhao Kai , Xu Chenggen , Liao Sijia , Ma Xinlong , Wang Xiaobai , Xu Chunming , Li Yongfeng
Published: December 2023

Heterocyclic aramid fibers (HAFs) with high strength and high modulus are widely used in the field of impact resistance. However, the weak interaction between molecular chains of HAFs seriously hinders the simultaneous improvement of strength and modulus. Herein, small addition (0.05 wt%) of nanosized acyl‐chloride‐activated graphene whiskers (NGW‐Cl) is used as reinforcements to simultaneously increase the strength and modulus of HAFs. The resultant NGW‐Cl/HAFs monofilament displays high tensile strength and modulus of 6.31 and 152 GPa, which are 19% and 18.8% higher than that of HAFs. The NGW‐Cl/HAFs multifilaments show high tensile strength and modulus of 36.16 and 1008 cN per dtex, which are 19.34% and 24.14% higher than that of HAFs. Especially, the dynamic modulus of NGW‐Cl/HAFs is up to 268.0 GPa at 200 HZ, which is increased by 92.8% compared with HAFs (139.0 GPa), showing a great application potential in high‐frequency vibration fields. Additionally, the strength and modulus of NGW‐Cl/HAFs impregnated multifilaments is up to 6.08 and 152 GPa, which is increased by 24.5% and 28.8% compared with HAFs. This apparent improvement is because the strong chemical bonding between NGW‐Cl and heterocyclic aromatic chains enhances heterocyclic aromatic chain interaction, inducing high crystallinity and orientation of HAFs.
Kelp Nanofiber‐Based Composite Membranes for Highly Efficient Osmotic Energy Conversion
Authors: Zhai Rui , Jiang Lulu , Chen Zhe , Zhang Xichun , Zhou Jiale , Ma Xiaoyan , Teng Chao , Zhou Yahong , Jiang Lei
Published: December 2023

The blue osmotic energy harvesting based on the nanofiber‐based layered membranes has received tremendous attention. However, the most nanofiber‐based ion‐selective membranes are suffering from uneconomical, environmentally unfriendly characteristics and a long growth cycle, as well as insufficient power density. In this work, kelp cellulose nanofibers (KCNFs) from green and inexpensive kelp with short growth cycle are compounded with hydrophilic MXene nanosheets to prepare KCNF/MXene nanofluidic membranes. Notably, the KCNF/MXene‐40 (40 is the mass fraction of KCNF) membrane with an aligned nacre‐like nanostructure achieves 3.03‐fold increase in mechanical strength compared to the pure MXene membrane. The ingenious combination of the surface charge of the MXene nanosheets and the space charge formed by negatively charged KCNFs endows the KCNF/MXene‐40 membrane with enhanced cation selectivity (≈0.85), high energy conversion efficiency of 24.04% and high power density of 66.23 W m−2 in a 500‐fold concentration gradient, which has exceeded most reported state‐of‐the‐art 2D nanofluidic membranes. More importantly, the membrane exhibits the exceptional long‐term stability with relatively unchanged power density within 6000 s. Under the conditions of the natural seawater and simulated river water, the KCNF/MXene‐based generator deliveries an output power density of ≈10.56 W m−2.
Remote Manipulation of TRPV1 Signaling by Near‐Infrared Light‐Triggered Nitric Oxide Nanogenerators for Specific Cancer Therapy
Authors: Wang Shuangling , Wang Yalin , Lv Jie , Xu Chunzhe , Wei Yuxin , Wang Guiying , Li Meng
Published: December 2023

Specific activation of transient receptor potential vanilloid member 1 (TRPV1) channels provides a new avenue for cancer treatment by inducing excessive Ca2+ influx. However, controllable manipulation of TRPV1 signaling for clinical application has remained elusive due to the challenge in finding a mild and effective method of exerting external stimulus without adverse side effects in living systems. Herein, a TRPV1‐targeting near‐infrared (NIR) triggered nitric oxide (NO)‐releasing nanoplatform (HCuS@PDA‐TRPV1/BNN6) based on polydopamine (PDA) coated hollow copper sulfide nanoparticles (HCuS NPs) is developed for specific cancer therapy. Upon NIR irradiation, the NO donor BNN6 encapsulated in NIR‐responsive nanovehicles can locally generate NO to activate TRPV1 channels and induce Ca2+ influx. This NIR controlled mode enables the nanoplatform to exert its therapeutic effects below the apoptotic threshold temperature (43°C), minimizing the photothermal damage to normal tissue. Integrating this special NO‐mediated therapy with HCuS NPs mediated chemodynamic therapy, the designed nanoplatform exhibits a boosted anticancer activity with negligible systematic toxicity. Together, this study provides a promising strategy for site‐specific cancer therapy by spatiotemporally controlled activation of surface ion channels, thus offering a solution to an unmet clinical need in cancer treatment.
Er‐Activated Hybridized Glass Fiber for Broadband Telecommunication
Authors: Wei Tianxia , Chen Jingfei , Yu Zhuoming , Han Yi , Zhang Ke , Huang Yupeng , Huang Xiaoyi , Li Xueliang , Feng Xu , Zhao Jian , Lv Shichao , Qiu Jianrong , Zhou Shifeng
Published: December 2023

With the rapid development of 5G networks, the Internet of Things, and new‐generation of AI, there are considerable demands on expanding the capacity of contemporary optical fiber communication systems. One of the most effective avenues involves the extension of the bandwidth of Er‐doped fiber amplifiers, but with limited success. Herein, an Er‐activated hybridized glass fiber are reported, which can help realize broadband telecommunication. The effect of element hybridization on the bandwidth of Er‐activated fiber is clarified and the structure‐optical response relationship is established. A two‐step deposition approach is proposed to overcome the immiscibility barrier of different hybridized elements, and Er‐activated fiber with uniform doping is constructed. The activated fiber presents excellent compatibility with commercial telecommunication systems, providing a small signal gain of >13 dB in the whole L‐band range and a maximum gain of 28 dB. Furthermore, the Er‐activated fiber amplifier device is successfully developed. It exhibits outstanding optical amplification performance with gain >24 dB in the range of 1580–1624 nm, gain fluctuation less than ±0.9 dB, and noise figure <6.5 dB. The results not only provide a new strategy for developing novel active broadband optical fibers, but a valuable solution for new‐generation large‐capacity optical fiber communication systems.
Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Authors: Zheng Chen‐Xi , Sui Bing‐Dong , Jin Yan
Published: December 2023

Stem cells, especially mesenchymal progenitors or mesenchymal stem cells (MSCs), possess an intrinsic property to form compact spheroid‐like assemblies, a phenomenon known as cell aggregation. In recent years, a growing body of researches have uncovered that this is a cross‐species conserved developmental event essential for initiating organogenesis in a variety of organs. Moreover, the self‐assembly property also contributes to the regenerative capacities of MSC aggregates in vivo with broad range of applications in tissue engineering. In this review, the principles of self‐assembled mesenchymal aggregation and its involvement in physiological organogenesis, as well as the construction approaches of engineering MSC aggregates and its application for organ regeneration are discussed. The authors aim to provide a speculative overview of the current understanding and the recent findings of cell aggregation, from both the developmental and the engineering perspectives, and thus offer insights into the understanding of stem cell biology and the establishment of novel organ regeneration strategies.
Nanosheet‐like MoO3 and conductive PANI electrodeposited on flexible carbon cloth for self‐supported solid‐state supercapacitor electrode
Authors: Sun Ran , Pei Yifei , Ren Huifang , Jin Yu , Hu Jie , Wang Qiyang , Wang Xuemei , Yan Manqing
Published: December 2023

In this paper, uniformly transition metal oxide (MoO3) nanosheets were electrochemically deposited on flexible carbon cloth (CC), and then conductive polyaniline (PANI) was orderly wrapped around their surface by electrochemical polymerization. The morphology and structure of as‐obtained self‐supported PANI/MoO3/CC electrode were investigated by FTIR, X‐ray diffraction, Raman, scanning electron microscope (SEM), transmission electron microscopy (TEM), and X‐ray photoelectron spectroscopy measurements in detail. Among all PANI/MoO3/CC electrode, the self‐supported PMC‐3 (deposition time of 300 s) has high specific capacitance of 841.6 F g−1 at current density of 0.5 A g−1 in the three‐electrode system, having specific capacitance of 595.7 F g−1 even at 10 A g−1. Novelty, the as‐assembled symmetrical capacitor is flexible and convenient with power density of 199.93 W kg−1 at the energy density of 9.69 Wh kg−1 and the energy density of 3.88 Wh kg−1 at power density of 4000 W kg−1. Thus, the electrochemical properties of the self‐supported PANI/MoO3/CC electrode were significantly improved, and the self‐supported electrodes are more competitive than other materials in practical application of clean energy storage systems.
Mechanistic insights into the thermal–mechanical aging of the interface of cross‐linked polyethylene/silicone rubber
Authors: Zhang Tianfeng , Zhang Yunxiao , Zheng Xin , Lin Wenxin , Zhang Zenghui , Chi Zhengnan , Zhang Jiarui , Teng Chenyuan
Published: December 2023

Cable accessory has the interface formed by cross‐linked polyethylene (XLPE)/silicone rubber (SiR), which is prone to surface discharge and thus causes the failure of cable system. This article conducts the simulated experiment of thermal–mechanical aging on the interface of XLPE/SiR. The interfacial breakdown and dielectric properties under different aging states are analyzed. It is found the interfacial aging process of XLPE can be divided into the recrystallization stage and the oxidation reaction stage. The former contributes to the interfacial roughness and thus the better insulating performance, whereas the latter leads to degradation of interface, and thus the worse insulating performance. In addition, combined with the established electric field model for the interface, the differences between thermal–mechanical aging and individual thermal aging on the interface are discussed. The sample under thermal–mechanical aging reaches the maximum interfacial breakdown voltage later than that under individual thermal aging, but their performance tends to be consistent in the later stage of aging.
One Pot Synthesis of Two Distinct Macrocycles: Aromatic p‐Benzihexaphyrin and Nonaromatic Doubly Fused p‐Benzihexaphyrin
Authors: Grover Vratta , Ravikanth Mangalampalli
Published: December 2023

Aromatic trithia p‐benzihexaphyrins and nonaromatic doubly fused trithia p‐benzihexaphyrins were synthesized in a one pot reaction by condensing a p‐benzithiophene based tetrapyrrane with three different bithiophene diols under acid catalyzed conditions. The aromatic and nonaromatic macrocycles showed clear differences in colour, NMR, absorption, and electrochemical properties. Theoretical studies supported the observed aromatic and nonaromatic characteristics, respectively, of the p‐benzihexaphyrins and their N‐fused derivatives.
Phytochemistry and Therapeutic Potential of Cupressus torulosa Needles Essential Oil from India
Authors: Bhalla Piyush , Chauhan Kiran , Chitme Havagiray R. , Varshney V. K.
Published: December 2023

Cupressus torulosa is an evergreen tree with a wide distribution in north‐western Himalayan region of India. Its needles have long been used in traditional medicine for anti‐inflammatory, antimicrobial, and wound‐healing properties. This study aimed to scientifically validate the traditional claim of the needles to treat inflammation by evaluating the chemical composition, antioxidant potential, and anti‐inflammatory activity of the essential oil extracted from the needles (CTEO) using hydro‐distillation. Qualitative and quantitative chemical composition of the CTEO was determined with the aid of GC‐MS and GC‐FID techniques. The major constituents of the CTEO were terpinen‐4‐ol (393.8±12.5 μg/mg), totarol (55.0±17.2 μg/mg), and sabinene (43.7±2.8 μg/mg). CTEO exhibited significant antioxidant activity when evaluated using DPPH free radical scavenging and reducing power assays. Furthermore, the CTEO demonstrated good anti‐inflammatory behavior in in vitro egg albumin denaturation assay, with an IC50 of 27.32 μg/mL. In vivo tests using carrageenan‐induced paw edema and xylene‐induced ear edema in rats showed significant effects at doses of 30 mg/kg for up to 1 hour. The significant discoveries not only support the established assertions about the anti‐inflammatory properties of C. torulosa needles but also highlight their potential as a useful resource in the growing herbal, complementary, and alternative medicine sectors.
Anti‐oncogenic Potential and Inflammation Modulatory Response of Green Synthesized Biocompatible Silver Nanoparticles
Authors: Nagarajaiah Shobha , Shivanna Giresha Aladahalli , Gopala Krishna Prashanth , Manikrao Gadewar Manoj , Praveen Manjappa , Nanda Nagappa , Urs Deepadarshan , Krishnappa Dharmappa Kattepura , Mutta Nagabhushana Bhangi , Rao Srilatha , Mahadeva Swamy Mallanna , Venkatesh Yatish Kalanakoppal
Published: December 2023

This study presents a novel approach to synthesizing silver nanoparticles (Ag NPs) using a solution combustion synthesis (SCS) method with Catharanthus roseus (C. roseus) leaf extract. The NPs were thoroughly characterized through X‐ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive X‐ray (EDX), Transmission electron microscopy (TEM), and Selected area electron diffraction (SAED), elucidating their crystal structure. Notably, the synthesized Ag NPs exhibited a significant dose‐dependent decline in viability of the MDA‐MB 231 breast cancer cell line, with an IC50 value of 13.3 μg/mL, underscoring their potential as potent anticancer agent. Beyond cytotoxicity, the study pioneers an investigation into the biocompatibility of Ag NPs by blood hemolsysis, providing critical insights into their safety and biomedical applicability. Furthermore, this research uncovers a distinctive facet of Ag NPs, revealing their inhibitory effects on the inflammatory enzyme secretory phospholipase A2 (sPLA2), a recognized biomarker for breast cancer. The demonstrated in vitro and in vivo inhibition of sPLA2 highlights the multifaceted potential of Ag NPs in not only targeting cancer cells but also modulating inflammatory responses associated with breast cancer, positioning the study at the forefront of advancements in nanomedicine and cancer therapeutics.
Electrochemical Oxygen Evolution Performance of Nitrogen‐Doped Ultra‐Thin Carbon Nanosheets Composite Ru1Co Single Atom Alloy Catalysts†
Authors: Deng Ziwei , Sun Zhiyi , Li Yaqiong , Pei Jiajing , Chen Wenxing
Published: December 2023

Comprehensive Summary

Energy transformation is imminent, and hydrogen energy is one of the important new energy sources. One of the keys to increasing the rate of hydrogen evolution during electrolysis is the use of high‐performance catalysts for oxygen evolution reactions (OER). Single‐atom alloys (SAAs) have garnered significant attention because they partially reduce costs and combine the advantages of both single‐atom catalysts (SACs) and alloy catalysts. Herein, an efficient pyrolysis strategy based on a mixing and drying process is designed to anchor ultra‐small Co cluster particles, combined with Ru single atoms dispersed on nitrogen‐doped ultra‐thin carbon nanosheets (Ru1Co SAA/NC). The prepared electrocatalyst exhibits superior OER activity and superb stability, demonstrating an overpotential of 238 mV for OER with a current density of 10 mA·cm–2 in 0.5 mol/L H2SO4. And we also utilized in‐situ XAS to detect the oxidation state of Ru sites during OER. All in all, this method achieves cost reductions and efficiency improvements through the design of SAAs, offering new prospects for the structural transformation of clean energy.
Secured tracing for group signatures from attribute‐based encryption
Authors: Perera Maharage Nisansala Sevwandi , Matsunaka Takashi , Yokoyama Hiroyuki , Sakurai Kouichi
Published: December 2023

This article presents a tracing mechanism for group signatures answering the security threats of malicious authorities and users' forgeries. The proposal weakens the high trust placed on the centralized tracing party in previous group signatures by decentralizing tracing power using a multiple tracer setting and limiting the tracers' access using attribute‐based encryption and the requirement of the group manager's agreement. We allow the group manager to control tracers identifying his group users. Instead of a centralized tracer, our setting has multiple tracers possessing attribute sets. Thus, after getting the group manager's permission, a tracer should satisfy the access policy in a given signature to identify the signer. On the other hand, our group signature scheme decentralizes the tracing key generation and removes the group manager's tracing ability. Thus, it ensures that only the attribute‐satisfying and permitted tracers can identify the signer. Moreover, this article delivers security against malicious users. It presents a verification process of access policy of the signatures to prevent users from utilizing invalid attributes for signing. In addition, the article delivers a collaborative tracing mechanism to satisfy attribute sets that a tracer fails to fulfill alone for identifying a signer. Thus, our tracing mechanism ensures security against malicious authorities and group users in group signatures. The article gives the general construction of the scheme and discusses the security.
Integrating Enhanced‐Efficiency Fertilizers in 4R Nutrient Management
Authors: Nigon Leanna Leverich
Published: December 2023

The 4R nutrient stewardship framework has brought us closer to improving our nutrient use efficiency. However, given the inherent “leakiness” of the N cycle, it is challenging to increase N use efficiency to optimum levels. Newer fertilizer technologies, like enhanced‐efficiency fertilizers (EEFs), are tools that can help achieve this goal. To determine if EEFs should be incorporated into nutrient management programs, growers and crop advisers should consider the various types of EEFs available, their functions within the soil, and the timing of application relative to the crop’s nutrient uptake demand. Earn 1 CEU in Nutrient Management by reading this article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
Direct inkjet writing type 1 bovine collagen/β‐tricalcium phosphate scaffolds for bone regeneration
Authors: Cabrera Pereira Angel , Tovar Nick , Nayak Vasudev Vivekanand , Mijares Dindo Q. , Smay James E. , Torroni Andrea , Flores Roberto L. , Witek Lukasz
Published: December 2023

Bone tissue has the capacity to regenerate under healthy conditions, but complex cases like critically sized defects hinder natural bone regeneration, necessitating surgery, and use of a grafting material for rehabilitation. The field of bone tissue engineering (BTE) has pioneered ways to address such issues utilizing different biomaterials to create a platform for cell migration and tissue formation, leading to improved bone reconstruction. One such approach involves 3D‐printed patient‐specific scaffolds designed to aid in regeneration of boney defects. This study aimed to develop and characterize 3D printed scaffolds composed of type I collagen augmented with β‐tricalcium phosphate (COL/β‐TCP). A custom‐built direct inkjet write (DIW) printer was used to fabricate β‐TCP, COL, and COL/β‐TCP scaffolds using synthesized colloidal gels. After chemical crosslinking, the scaffolds were lyophilized and subjected to several characterization techniques, including light microscopy, scanning electron microscopy, and x‐ray diffraction to evaluate morphological and chemical properties. In vitro evaluation was performed using human osteoprogenitor cells to assess cytotoxicity and proliferative capacity of the different scaffold types. Characterization results confirmed the presence of β‐TCP in the 3D printed COL/β‐TCP scaffolds, which exhibited crystals that were attributed to β‐TCP due to the presence of calcium and phosphorus, detected through energy dispersive x‐ray spectroscopy. In vitro studies showed that the COL/β‐TCP scaffolds yielded more favorable results in terms of cell viability and proliferation compared to β‐TCP and COL scaffolds. The novel COL/β‐TCP scaffold constructs hold promise for improving BTE applications and may offer a superior environment for bone regeneration compared with conventional COL and β‐TCP scaffolds.
Predicting the activity of methoxyphenol derivatives antioxidants: II—Importance of the nature of the solvent on the mechanism, a DFT study
Authors: Khelifi Roumaissa , Latelli Nadjia , Charifi Zoulikha , Morell Christophe , Chermette Henry
Published: December 2023

The various mechanisms of primary antioxidant action of a series of 2‐Methoxyphenols are investigated in the present work. The electronic properties have just been studied in a joint article, so that we focus here on Hydrogen Atom Transfer (HAT), Single Electron Transfer–Proton Transfer (SET–PT) and Sequential Proton‐Loss Electron‐Transfer (SPLET) mechanisms. The two computational approaches used in the previous study of the structure and reactivity of these compounds [Computational and Theoretical Chemistry 1229 (2023) 114287] provide identical mechanisms trends in gas phase. In gas media, hydrogen atom transfer (HAT) is more favored. On the contrary, the solvent polarity has a significant effect on the mechanism of the antioxidant activity, since the polarity of the solvent increases the contribution of the SPLET mechanism.
Multi‐institutional retrospective review of acute generalized exanthematous pustulosis (AGEP) induced by hydroxychloroquine
Authors: Bang Alexander S. , Blank Nina R. , Fox Lindy , Ko Justin , Worswick Scott , Harp Joanna
Published: December 2023

Background

Acute generalized exanthematous pustulosis (AGEP) is a rare and severe cutaneous drug eruption. Hydroxychloroquine (HCQ) is one of the known culprit drugs with less than 60 cases reported in the literature, and may have a more severe clinical presentation compared to AGEP induced by other drugs. There are no standardized management strategies for HCQ‐induced AGEP outside of drug discontinuation.

Objectives

Characterize the clinical presentation of HCQ‐induced AGEP and management strategies.

Methods

Retrospective chart review of nine patients clinically diagnosed with HCQ‐induced AGEP using the EuroSCAR score from 2017 to 2022 at four academic medical centres in the United States.

Results

All patients in our series were female and the median age was 52. Four patients initially presented with fever, and eight patients had neutrophilia. Median time to rash was 15 days. Biopsies obtained in six patients showed typical characteristics of AGEP. In most patients, rash morphology consisted of generalized pinpoint pustules atop atypical targetoid lesions and annular plaques. Five patients were hospitalized for AGEP. All patients were treated with methylprednisolone and/or prednisone, and the average days treated with systemic corticosteroids was 35.

Conclusions

Our case series is the largest to date describing HCQ‐induced AGEP. Clinicians should be wary that HCQ‐induced AGEP may present with a longer latency period after drug initiation and with atypical targetoid and annular lesions. Early initiation of systemic corticosteroids should be considered due to the severity of this drug reaction with addition of cyclosporine in refractory cases.
On the blow‐up for nonlinear Schrödinger equation with inhomogeneous perturbation
Authors: Zhang Mao , Zhang Jian
Published: December 2023

We devote to the analysis of blow‐up solutions for the nonlinear Schrödinger equation with inhomogeneous perturbation. Firstly, we get the sharp threshold of global existence and blow‐up for the Cauchy problem. Then, we show the mass concentration properties and the limiting behavior of blow‐up solutions. At last, we prove the nonexistence of the minimal mass blow‐up solution by using the limiting behavior of blow‐up solutions.
Electronic structure of 1,3‐diphenyl‐2‐azaallenyl radical cation
Authors: Yim Daniel , Kim Young‐Kwan , Park Ji Hun , Kim Hyungjun
Published: December 2023

Quantum chemical simulations were conducted to elucidate the electronic structure of the 2‐azaallenyl radical cation, a key intermediate in several [3 + 2]‐cycloadditions initiated by the oxidation of 2H‐azirine. We propose one additional Lewis structure in resonance with the commonly accepted two Lewis structures for the model system of 1,3‐diphenyl‐2‐azaallenyl radical cation, drawn from comprehensive theoretical data including molecular shape, bond order analysis, partial atomic charges, and spin densities. In addition to the ground state chemistry, the chemical structure of excited state species can be also understood with these three Lewis structures. Theoretical data imply that a newly suggested one mainly accounts for the ground state structure, and the excited state structure is better represented by the previously reported ones. Our claim is further bolstered by the prediction of the excited state geometries of the dicationic and neutral species. This research presents the extended set of Lewis structures for a better understanding electronic structure of 2‐azaallenyl radical cation.
Report of the Nomenclature Committee for Fungi: 22
Authors: May Tom W. , Lendemer James C.
Published: December 2023

Information on appointments to the Fungal Nomenclature Bureau is provided. Appointments to two Special‐purpose Committees are reported. The following four generic names are recommended for conservation: Bilimbia with a conserved type; Coccotrema against Lepolichen; Fuscidea against Maronea; and Leptogium (lichenized Ascomycota) with a conserved type. The following two generic names are not recommended for conservation: Marcelaria against Buscalionia; and Variolaria Pers. against Lepra and Variolaria Bull. The following seven species names are recommended for conservation: Lecidea parmeliarum (Abrothallus parmeliarum) against Endocarpon parasiticum; Lichen cervinus (Acarospora cervina) with a conserved type; L. ferrugineus (Blastenia ferruginea) with a conserved type; L. flavus Bellardi (Pleopsidium flavum) against L. flavus Schreb.; Megaspora verrucosa (Ach.) Arcadia & A. Nordin against M. verrucosa Hafellner & V. Wirth.; Umbilicaria spodochroa with a conserved type and with that spelling; and Usnea fulvoreagens with a conserved type. The following three species names are not recommended for conservation: Alectoria fuscescens (Bryoria fuscescens), nom. cons., against the additional names Usnea implexa, A. capillaris, A. cana, A. rubens, A. fuscidula, A. degenii, A. forissii, A. ostrobotniae, A. kuemmerleana, A. haynaldiae, A. achariana, A. lanestris, A. prostratosteola, and A. viridescens; Lichen fuscovirens (Collema fuscovirens) against L. pulcher; and Ochrolechia szatalaensis against Pertusaria poriniza. The following two species names are recommended for rejection under Art. 56: Lecidea cornea and Lichen conspurcatus. The following generic name is recommended for rejection under Art. 56: Huea (and the original proposal to conserve Huea with a conserved type is not recommended). It is recommended that the species name Variolaria torta not be rejected under Art. 56. The proposal to conserve Pertusariaceae against Variolariaceae is considered unnecessary because the latter name is illegitimate. The Nomenclature Committee for Fungi could not arrive at a recommendation on the proposal to conserve Lagerheimia (De Toni) Chodat against Lagerheima Sacc. and nor resolve requests for binding decisions on whether the pair Geisleria Nitschke and Geissleria Lange‐Bert. & Metzeltin and the pair Lagerheima Sacc. and Lagerheimia (De Toni) Chodat are sufficiently alike to be confused – but these three items have now been resolved by the General Committee.
Report of the General Committee: 28
Authors: Wilson Karen L.
Published: December 2023

Decisions of the General Committee are reported on the proposals in Report 24 of the Permanent Nomenclature Committee for Algae and Report 14 of the Permanent Nomenclature Committee for Bryophytes, and on two proposals in Report 73 of the Permanent Nomenclature Committee for Vascular Plants.
Broadening participation in STEM through equity-minded high-impact practices: a multimodal systematic review
Authors: Ives Jillian , Falk Joni , Drayton Brian
Published: December 2023

High-impact practices (HIPs), such as undergraduate research, first-year seminars, and learning communities, have been shown to generally advance college student success. However, there are often disparities in access, participation, and outcomes between white and racially/ethnically minoritized students. While scholars have critiqued HIPs and provided alternative approaches to better serve minoritized students, we know little about how federally funded programs aiming to broaden participation can serve as a mechanism advance equity. Drawing on the literature, we developed an equity-minded HIP framework to critically examine the prominence and characteristics of 38 programs aiming to broaden participation in undergraduate US STEM education funded by the National Science Foundation. We conducted a systematic examination of multimodal data from the STEM for All Multiplex repository. Findings reveal most programs included only one to two HIPs, with undergraduate research being most prominent followed by internships. Most programs included only a few elements of equity-minded design, such as providing students additional resources and faculty training, and implemented HIPs to include peer and faculty interactions. Last, most programs utilized cognitive, psychosocial, or sociocultural measures to assess the benefits to students. Only a few measured equity-mined outcomes pertaining to institutional change such as policies, resources, and practices. We highlight two exemplar programs and offer recommendations for researchers and funders to more effectively implement equity-minded HIPs to broaden participation in undergraduate STEM education.
The Effect of Physical and Virtual Inquiry-Based Experiments on Students’ Attitudes and Learning
Authors: Papalazarou Nikolaos , Lefkos Ioannis , Fachantidis Nikolaos
Published: December 2023

Involving students in laboratory and inquiry-based activities can help them understand the concepts of physics. However the learning process should not only focus on the concepts. Moreover, the advantages of using virtual or physical labs are still under examination. The purpose of this study is to analyse which of the two modes (virtual or physical) is the most effective for high-school students, in terms of conceptual understanding and attitudes. The criteria for this comparison are (a) the contribution of these two modes to the improvement of conceptual understanding and (b) the students’ attitudes towards both modes of laboratory. The participants were high-school students of 3rd grade in two different groups. For the purpose of the study, four educational scenarios were created: two in the field of Mechanics and two in that of Electricity. The study revealed no statistically significant difference regarding students’ experimenting in either lab mode. Moreover, students’ attitudes towards both virtual and physical labs were similarly positive. We assume that these results may contribute to a broader perspective on choosing the lab mode when designing activities, given the fact that both the understanding and attitudes of the students are similar in the cases examined. Thus, the final choice of modality should be based on other factors, such as the adequacy of equipment, the educational conditions (e.g. distance education) and the specific learning goals set by the teacher.
An extended 2D Gao beam model
Authors: Dyniewicz Bartłomiej , Shillor Meir , Bajer Czesław I.
Published: December 2023

This work derives and simulates a two-dimensional extension of the nonlinear Gao beam, by adding the cross-sectional shear variable, similarly to the extension of the usual Bernoulli–Euler beam into the Timoshenko beam. The model allows for oscillatory motion about a buckled state, as well as adds vertical shear of the cross sections, thus reflecting better nonlinear thick beams. The static model is derived from the principle of virtual elastic energy, and is in the form of a highly nonlinear coupled system for the beams transverse vibrations and the motion of the cross sections. The model allows for general distributive transversal and longitudinal loads and a compressive horizontal load acting on its edges. The model is simulated numerically, using the dynamic version for better insight into the steady solutions. The terms that distinguish our numerical solutions from the solutions of the Gao beam, described in the literature, are highlighted. The numerical scheme and its characteristic finite element matrices allow us to obtain simulation results that demonstrate the type of vibrations of our extended and modified beam, and also the differences between these solutions and those of the Gao beam model.
Numerous insertions of mitochondrial DNA in the genome of the northern mole vole, Ellobius talpinus
Authors: Kuprina Kristina , Smorkatcheva Antonina , Rudyk Anna , Galkina Svetlana
Published: December 2023

Background

Ellobius talpinus is a subterranean rodent representing an attractive model in population ecology studies due to its highly special lifestyle and sociality. In such studies, mitochondrial DNA (mtDNA) is widely used. However, if nuclear copies of mtDNA, aka NUMTs, are present, they may co-amplify with the target mtDNA fragment, generating misleading results. The aim of this study was to determine whether NUMTs are present in E. talpinus.

Methods and results

PCR amplification of the putative mtDNA CytB-D-loop fragment using ‘universal’ primers from 56 E. talpinus samples produced multiple double peaks in 90% of the sequencing chromatograms. To reveal NUMTs, molecular cloning and sequencing of PCR products of three specimens was conducted, followed by phylogenetic analysis. The pseudogene nature of three out of the seven detected haplotypes was confirmed by their basal positions in relation to other Ellobius haplotypes in the phylogenetic tree. Additionally, ‘haplotype B’ was basal in relation to other E. talpinus haplotypes and found present in very distant sampling sites. BLASTN search revealed 195 NUMTs in the E. talpinus nuclear genome, including fragments of all four PCR amplified pseudogenes. Although the majority of the NUMTs studied were short, the entire mtDNA had copies in the nuclear genome. The most numerous NUMTs were found for rrnL, COXI, and D-loop.

Conclusions

Numerous NUMTs are present in E. talpinus and can be difficult to discriminate against mtDNA sequences. Thus, in future population or phylogenetic studies in E. talpinus, the possibility of cryptic NUMTs amplification should always be taken into account.
Spin-outs’ knowledge legacies and parent hostility: a competitive dynamics view
Authors: Walter Sascha G.
Published: December 2023

This study adopts a competitive dynamics perspective to illuminate how and when different types of knowledge transferred by a spin-out trigger parent hostility. Specifically, I propose based on the awareness-motivation-capability framework that (1) transfers of market-related and technology-related knowledge will yield hostility and that (2) market commonality, resource similarity, and competitive intensity will exacerbate this effect. Findings from 207 spin-outs support several of my hypotheses. The study contributes to the extant literature by providing a more nuanced view on knowledge legacies, in particular regarding their interplay with a spin-out’s competitive positioning.