Expert consensus on culture of patient derived tumor organoids and organoids based drug sensitivity testing
Authors:   Ruijin  Hospital,  Shanghai  Jiao  Tong  University  School  of  Medicine, Batul Ekmu ,   Chengdu  AimingMed  Medical  Laboratory, Chen Bing , Chen Fang ,   Jiangyou  Second  People's  Hospital, Cheng Liming ,   Tongji Hospital,   Tongji Medical College,   Huazhong  University  of  Science  and  Technology, Chen Shi ,   Department  of  Hepatopancreatobiliary  Surgery,   Fujian  Provincial  Hospital, Chen Xueqin ,   Hangzhou  First  People's  Hospital, Deng Kun ,   The  Third  Affiliated  Hospital  of  Chongqing  Medical  University, Ding Shigang ,   Department  of  Gastroenterology,  Peking  University  Third  Hospital, Fan Jiali ,   Chengdu  AimingMed  Medical  Laboratory, Gao Quansheng ,   Military  Medical  Sciences  Academy, Gou Jialin ,   Chengdu  AimingMed  Medical  Laboratory, Han Kun ,   Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Hao Xinyu ,   Department  of  Traditional  Chinese  Medicine,  Peking  University  Third  Hospital, He Yuedong ,   West  China  Second  University  Hospital,  Sichuan  University, Hou Tieying ,   Shenzhen  Nanshan  People's  Hospital, Hong Zhanying ,   School  of  Pharmacy,  Naval  Medical  University, Li Hui ,   Chengdu  AimingMed  Medical  Laboratory, Li Jing ,   Chengdu  AimingMed  Medical  Laboratory, Li Lin ,   Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Li Tao ,   The  First  Affiliated  Hospital  of  Anhui  Medical  University, Li Xiaoqin ,   Urumqi  Maternal  and  Child  Health  Hospital, Liu Jinbo ,   The  Affiliated  of  Southwest  Medical  University, Liu Jiyan ,   Department  of  Biotherapy,  West  China  Hospital,  Sichuan  University, Lin Xin ,   Chengdu  AimingMed  Medical  Laboratory, Luo Yang ,   Chongqing  General  Hospital,  School  of  Medicine,  Chongqing  University, Peng Jing ,   Tongji  Hospital,   Department  of  Hepatopancreatobiliary  Surgery, Peng Mingting ,   National  Health  Commission  Clinical  Laboratory  Center,   National  Health  Standards  Committee  Clinical  Inspection  Standards, Shen Chongyang ,   Chengdu  University  of  Traditional  Chinese  Medicine, Sun Hongyu ,   The  General  Hospital  of  Western  Theater  Command, Wu Zhibing ,   Cancer  Center,  Zhejiang  Hospital  Affiliated  to  Zhejiang  University  School  of  Medicine, Xia Bing ,   Hangzhou  Cancer  Hospital, Xia Dan ,   Chengdu  AimingMed  Medical  Laboratory, Xing Huayang ,   Hangzhou  AimingMed  Technologies  Co.,  Ltd, Xu Chong ,   Shanghai  Center  for  Clinical  Laboratory, Yang Li ,   Chengdu  AimingMed  Medical  Laboratory, Yang Zhenyu ,   Shanghai  Clinical  Research  and  Trial  Center, Yang Zhirong ,   Deyang  People's  Hospital, You Mingliang ,   Hangzhou    AimingMed    Tumor    Organoids    Enterprise    High-tech    Research    and    Development Center, Yi Xianghua ,   Tongji  Hospital,  School  of  Medicine,  Tongji  University, Zhang Bin ,   Department  of  Obstetrics  &  Gynecology,  The  First  Affiliated  Hospital,  Fujian  Medical  University, Zhang Fengbo ,   The  First  Affiliated  Hospital  of  Xinjiang  Medical  University, Zhang Xiao ,   Guangzhou  Institute  of  Biomedicine  and  Health,  Chinese  Academy  of  Sciences, Zhou Maohua ,   The  Affliated  Panyu  Central  Hospital  of  Guangzhou  Medical  University, Zhou Yiwen ,   Southern  Medical  University  Shenzhen  Hospital, Zhou Yi ,   Hangzhou  AimingMed  Technologies  Co.,  Ltd., Wu Lijuan ,   Chengdu  AimingMed  Medical  Laboratory,   School  of  Medicine,  Southwest  Jiaotong  University,   The  General  Hospital  of  the  Western  Theater  Command,   Medical  Inspection  Quality  Management  Committee  of  China  Medical  Quality  Management Association
Published: October 2024

The precision treatment of cancer has consistently been a significant issue in clinical management as well as medical research. With the rapid development and advances towards clinical application of organoids technology, the use of organoids derived from both normal and cancer tissues for pathophysiology studies, treatment regimen development, and drug screening has become increasingly prevalent. This document compiles insights from dozens of nationwide experts and scholars in the field of tumor organoids drug sensitivity testing. It discusses the entire process of tumor organoids drug sensitivity testing, with the intent to provide expert guidance for laboratories interested in conducting clinical testing and application research related to cancer precision therapy.