bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of the walking independence on lower extremity and trunk muscle activity during straight-leg raising following incomplete cervical cord injury
Authors: Sugimoto Tatsuya , Yoshikura Ryoto , Maezawa Toshiyuki , Mekata Kojiro , Ueda Yuya , Kawaguchi Hiroshi , Izumi Shintaro
Published: February 2024

The purpose of this study was to compare the acceleration and surface electromyography (EMG) of the lower extremity and trunk muscles during straight-leg raising (SLR) in patients with incomplete cervical cord injury according to their levels of walking independence. Twenty-four patients were measured acceleration and EMG during SLR held for 10 s. Data were analyzed separately for the dominant and nondominant sides and compared between the nonindependent (NI) and independent (ID) groups based on their levels of walking independence. Frequency analysis of the EMG showed that the high-frequency (HF) band of the contralateral biceps femoris (BF) in the ID group and bands below the medium-frequency (MF) of the BF and the HF and MF bands of the rectus abdominis in the NI group were significantly higher during dominant and nondominant SLR. During the nondominant SLR, the low-frequency band of the internal oblique and the MF band of the external oblique were significantly higher in the NI group. The ID group mobilized muscle fiber type 2 of the BF, whereas the NI group mobilized type 1 of the BF and types 2 and 1 of the trunk muscles to stabilize the pelvis. This result was more pronounced during the nondominant SLR.
Protective factors against the emotional impact of the pandemic in adults with autism spectrum disorders (ASD) and intellectual disability (ID)
Authors: Jodra Marina , García-Villamisar Domingo
Published: February 2024

The pandemic has had very negative effects on the mental health of the population, especially in people with autism spectrum disorders (ASD) and intellectual disability (ID). We analyzed whether social communication, quality of life, and anxiety explain changes in the emotional impact of the pandemic in 60 adults with ASD and ID. Correlations between the study variables were analyzed and subsequently a multiple regression analysis was performed. The results show that communication writing, leisure and well-being index, explain 31% of the dependent variable. The well-being index (PWI) contributes significantly to improving the fit of the model, as indicated by β value. The remaining variables, communication writing and leisure socialization, do not contributed significantly to improving the fit of the model. Quality of life is the only variable that can explain changes in the emotional impact of the pandemic in the study population. This finding should guide future psychoeducational interventions and services for adults.
Self-adjuvanted l-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses
Authors: Chung Jin Teng , Rafiei Mehrnoosh , Chau Ying
Published: February 2024

Antigens are delivered in self-adjuvanted arginine-modified dextran-based nanogels to the dendritic cells in promoting antigen specific cellular immunity.
Dynamic monitoring of the fibrosis disease by a collagen targeting near infrared probe
Authors: Zhang Xiaoke , Yang Qianwen , Zhou Sensen , Li Cheng , Jiang Xiqun
Published: February 2024

A H2O2-sensitive macromolecular optical probe which can effectively bind to collagen was developed for real time noninvasive visualization of fibrotic tissues.
Screening, separation and identification of metal-chelating peptides for nutritional, cosmetics and pharmaceutical applications
Authors: Echavarría Jairo Andrés Camaño , El Hajj Sarah , Irankunda Rachel , Selmeczi Katalin , Paris Cédric , Udenigwe Chibuike C. , Canabady-Rochelle Laetitia
Published: February 2024

Metal-chelating peptides, which form metal–peptide coordination complexes with various metal ions, can be used as biofunctional ingredients notably to enhance human health and prevent diseases.
Strategies for developing layered oxide cathodes, carbon-based anodes, and electrolytes for potassium ion batteries
Authors: Lin Yicheng , Luo Shaohua , Cong Jun , Li Pengwei , Yuan Xueqian , Yan Shengxue
Published: February 2024

The progress in the development of layered metal oxide cathodes, carbon-based anodes, and electrolytes for potassium ion batteries is reviewed. Specific development suggestions, concise perspectives, and strategies are provided.
Low platinum loading electrocatalyst supported on a carrier derived from carbon dots doped ZIF-67 for the ORR and zinc–air batteries
Authors: Yang Lijing , Ma Junhong , Liu Yuemei , Ma Chaoyun , Yu Xue , Chen Zhaohui
Published: February 2024

A low Pt loading electrocatalyst is constructed by pyrolyzing CDs and ZIF-67 complex, which can improve the ORR performance by adjusting Pt electronic structure.
Imidazolium-based zwitterionic liquid-modified PEG–PLGA nanoparticles as a potential intravenous drug delivery carrier
Authors: Dasanayake Gaya S. , Hamadani Christine M. , Singh Gagandeep , Kumar Misra Sandeep , Vashisth Priyavrat , Sharp Joshua S. , Adhikari Laxmi , Baker Gary A. , Tanner Eden E. L.
Published: February 2024

Zwitterionic liquid surface-modified PEG–PLGA nanoparticles are developed to explore their potential as intravenous drug delivery carriers via RBC hitchhiking and affinity towards triple-negative breast cancer cells.
Galvanic replacement-induced preparation of bloom-like Pt23Ni77 for methanol coupled efficient hydrogen production
Authors: Zhao Jin , Wang Jinjin , Wang Ying , Zhang Junming , Luo Ergui , Lv Baoliang , Hu Tianjun , Jia Jianfeng
Published: February 2024

Galvanic replacement reaction (GRR) leverages the difference in metal reduction potentials to regulate the structure of nanomaterials.
Adsorption of hexavalent chromium from wastewater using polyaniline-coated microcrystalline cellulose nanocomposites
Authors: Dewa Lovejoy , Tichapondwa Shepherd Masimba , Mhike Washington
Published: February 2024

In this study, the effectiveness of microcrystalline cellulose (MCC) as an adsorbent for the removal of hexavalent chromium, Cr(vi), from synthetic wastewater was enhanced through functionalization with polyaniline (PANI).
Enhancing continuous-flow reactions via compression-molding of solid catalysts and dilutants in packed-bed systems
Authors: Kobayashi Kwihwan , Tanaka Teruhiko , Kon Yoshihiro , Kawanami Hajime , Koumura Nagatoshi
Published: February 2024

In this study, we present an improved packed-bed system designed for continuous-flow reactions using platinum (Pt)-black powder and silica gel (SiO2). The Pt-leaching from the reaction column is suppressed via compression-molding of the Pt and SiO2.
Superior energy storage properties in lead-free NaNbO3-based relaxor antiferroelectric ceramics via a combined optimization strategy
Authors: Liu Huanwei , Niu Xiang , Wang Ting , Tang Yi , Xu Zihao , Lu Xubing , Zhang Xiangbin , Zeng Wenhan , Xu Mingtao , He Houzhu , Jiang Yuleng , Gong Weiping , Zhao Xiaobo , Yao Yingbang , Tao Tao , Liang Bo , Lu Sheng-Guo
Published: February 2024

A stable relaxor AFE R phase in NaNbO3-based ceramics is achieved. An excellent Wrec of ∼11.09 J cm−3 and an η of ∼85.7% were realized at 1200 kV cm−1 for x = 0.30 thick film ceramic.
Unravelling polymorphism-driven luminescence in GFP chromophore analogues: insights into the phase transition and morphology-dependent optical waveguide properties
Authors: Dabke Niteen B. , Raut Yash , Mali Bhupendra P. , Pandya Rinu , Vanka Kumar , Manoj Kochunnoonny , Gonnade Rajesh G.
Published: February 2024

Polymorphs of GFPc analogs A and B display differences in their optical waveguiding properties in 1D and 2D depending on the crystal shapes. Furthermore, Form B1 demonstrates efficient optical waveguiding capabilities even when the crystal is bent.
Through-space charge transfer within single-component organic crystal: visual detection and rational regulation
Authors: Liu Zhenjiang , Ren Jia , Zhang Hui , Wang Yunsheng , Li Xiaoning , Wang Jiaqiang , Fang Manman , Yang Jie , Tang Ben Zhong , Li Zhen
Published: February 2024

Organic luminogens with through-space charge transfer (TSCT) were obtained through connecting donor and acceptor with non-conjugated alkyl chains. The intensity of TSCT could be mapped by the corresponding room temperature phosphorescence (RTP) effect.
2-cyanopyridine derivatives enable N-terminal cysteine bioconjugation and peptide bond cleavage of glutathione under aqueous and mild conditions
Authors: Yano Tetsuya , Yamada Takahiro , Isida Hiroaki , Ohashi Nami , Itoh Toshimasa
Published: February 2024

Inspired by the chemical reactivity of apalutamide, an efficient method for N-terminal cysteine bioconjugation with 2-cyanopyridine derivatives has been developed.
Polymer-derived silicon oxycarbonitride bowls with hollow structures and hetero-nanodomains for electromagnetic wave absorption
Authors: Xu Rupan , Zhou Jie , Huang Weiquan , Yu Gaoyuan , Guo Liqun , Huang Xiaogu , Shao Gaofeng
Published: February 2024

The surface concave structure and inner cavity improve impedance matching and multiple reflections/scattering. The hetero-nanodomains create dipolar and interfacial polarizations.
The Hansen solubility approach towards green solvent processing: n-channel organic field-effect transistors under ambient conditions
Authors: Deneme Ibrahim , Yıldız Tevhide Ayça , Kayaci Nilgun , Usta Hakan
Published: February 2024

This paper demonstrates a rational Hansen solubility approach for the development of green solvent processing in ambient-stable n-channel OFETs. Unique thermodynamic findings are revealed for molecular semiconductors.
Theoretical Aspects of State Regulation of Agrarian and Industrial Complex
Authors: Gayduk Vladimir , Кhaliapin Alexey
Published: February 2024

In work author’s treatments of concepts «agrarian policy» and «the state economic regulation of agrarian sector of economy» are presented. Principal causes of state regulation of agrarian and industrial complex from the point of view of the countries with more perfect market economy are generalized and specified. Author’s vision of methods by means of which the state should carry out the regulating functions in agrarian sphere is presented.
Results of studies of salt resistance of conifer trees and its role in improving the ecological state of the Aral region
Authors: Kurbanov Kuvvat , Allamuradova Mehrijemal , Kurbanov Babageldi , Haydarov Gurbangeldi , Kazakova Hayitzan
Published: February 2024

In this work it was described the results of many years of scientific research on taxonomic, biomorphological, geographical and ecological analysis of the dendroflora of the Dashoguz region, as well as the results of studies of the salt tolerance of coniferous trees.
Use of acid gases in the production of sodium sulphide
Authors: Nimchik Alexey , Pulatov Golibjon , Yusupov Farkhod , Haydarov Bekzod , Kambarov Asadjon
Published: February 2024

This study was conducted to check the possibility of hydrogen sulfide as a material to produce sodium sulphide. It is a harmful substance that is released during production in many industrial production processes. In laboratory and semi-industrial conditions, the possibility of producing hydrogen sulfide using associated acid gases from hydrocarbon production as raw materials has been established. The resulting purified hydrogen sulfide, absorbed by a solution of sodium hydroxide, is a promising raw material in the production of sodium sulfide. The experiments on the production of sodium sulfide from natural gas processing waste, which contains hydrogen sulfide, showed the promise of using the proposed method. A new method and technology for the production of sodium sulfide has been developed, while the cost of the resulting product has been reduced due to the available local cheap raw materials, widely used in the chemical and mining industries and the simplification of the technological scheme and equipment used. Due to the developed method for the production of Na2S, it is possible to utilize a large number of waste gases from hydrocarbon production, as a result of which both environmental problems of the regions are solved, and it is also possible to obtain a product with great economic profitability.
The effect of the viscosity of borehole products on the operation of pumping equipment and the coefficient of oil recovery
Authors: Mingulov Shamil , Mukhametshin Vyacheslav Sh. , Vafin Rif , Gilyazetdinov Ruslan , Kobishcha Dina
Published: February 2024

The purpose of this work is to develop, create and adapt the technology for the implementation of viscosity determination of the extracted products. The scientific novelty of the work is based on the use of an up-to-date physical and mathematical apparatus for solving problems of effective field development, In the article for the Geppler viscometer to measure the viscosity of wellhead products in field conditions, the principle of viscosity measurement based on measuring the rolling time of a ball in a calibrated tube is proposed. The device allows you to measure the viscosity of both an oil-water medium with a residual amount of dissolved gas and completely degassed products. In laboratory conditions, a universal dependence of the viscosity of well products on the temperature of the liquid and its water content was obtained for oils from a number of fields in the Republic of Tatarstan, which allows calculating viscosity at different temperatures and water levels using a single viscosity measurement. An example of the application of the results of measuring the viscosity of products at the wellhead by a developed device for diagnosing the operation of a well under complicated conditions using a dynamic model, the error level of which allows it to be used and the data obtained to be successfully applied in the development and design of various measures, including those implemented to increase the inter-repair period of well operation. The model allows you to calculate loads and obtain a theoretical dynamogram of the pump's operation on liquids of various viscosities. The results obtained will significantly increase the efficiency of oil recovery and will in one way or another stimulate subsurface users to develop hard-to-recover reserves of liquid hydrocarbons, which will expand the activities of the fuel and energy complex of the Russian Federation.
The state and prospects of geothermal energy development in Uzbekistan
Authors: Ismailov Bakhtiyar , Ibragimov Aziz , Gafurov Timur , Mumindjanov Talad , Rakhim Tursunmetov
Published: February 2024

The article considers topical issues of the state of resources and prospects of use of geothermal energy taking into account foreign experience in the republic as one of the types of renewable energy source, connected, first of all, with depleted fossil fuel reserves and dependence on imports (mainly oil and gas imports). Uzbekistan has huge resources and reserves of geothermal resources, the projected resources of which at accessible depths (up to 5-6 km) are 4-6 times higher than those of hydrocarbons. The high economic efficiency of geothermal resources is determined by their thermal potential, which can be achieved by developing integrated schemes for each geothermal field. All this makes it possible to consider geothermal waters of the republic as the basis of development of geothermal energy in the republic.
Analysis of magnetohydrodynamic phenomena in a single spatial electromagnetic field
Authors: Ibragimova Ozoda , Khalikov Abdulhak
Published: February 2024

The paper presents the results of the analysis of the disinfection of water by a pulsed single spatial electromagnetic field. The origin of the fluid pressure in the pipe is calculated and graphically presented as the interaction of a single spatial field and the current of moving charges. It is proved that a single spatial field enhances the process of dissociation of water in a liquid solution. The orbital electrons of two hydrogen atoms and one oxygen atom of water create a strong inhomogeneous electric field around themselves, which leads to the separation of the liquid solution and the compounds contained in it into elements. The purpose of the work is to study magneto hydrodynamic phenomena spatial electromagnetic field disinfection of water by a single spatial electromagnetic field, The theory of a single spatial field involves the interaction of four fields of pulsed electromagnetic, pulsed electric, permanent magnetic and gravitational. The theory of a single spatial field is substantiated, which allows us to consider the issues of effective disinfection, desalination and purification of water, as well as to study the effects of electric, magnetic fields and electromagnetic waves on physical, chemical and biological processes occurring in liquids.
Modernization of an existing microwave installation for microwave processing of biological substrates
Authors: Tukhvatullin M.I.
Published: February 2024

One of the urgent tasks for breeding and seed centers producing elite and superelite seeds is to reduce excess moisture, which leads to reduced storage, reduced efficiency of use, deterioration in the commercial quality of products after drying, and contributes to the rapid development of pathogenic pathogens that render grain unusable ( average losses of grain without drying are 15...18%). Existing methods of reducing seed moisture are the use of drying devices, the significant disadvantages of which are: high energy intensity, the use of diesel and gas fuels, which pollute the environment, and the high cost of installations, which increases the cost of the final product. It is proposed to develop an energy-saving technology to obtain agricultural products with improved qualities, expanding the functionality of the use of equipment both for seed production enterprises and agricultural enterprises, as well as for processing polycaproamide threads used as suture material in veterinary medicine. Ultrahigh-frequency electrotechnological installations, which use the energy of electromagnetic oscillations of ultrahigh frequency, can carry out thermal microwave modification of biological substrates and non-thermal microwave modification of polycaproamide threads. The paper presents an installation with a hybrid-type working chamber, in which thermal and non-thermal microwave modification of biological substrates and polycaproamide threads is simultaneously carried out. The presented installation is cheaper, it requires one rather than two microwave generators, and it occupies less space than two separate installations.
Methods of identification of phytopathogenic bacteria Pectobacterium carotovorum subsp. carotovorum
Authors: Ryskaliyeva B.Zh. , Bogdanov I.I. , Ryskaliyev M.Zh.
Published: February 2024

Bacterial infections are a global problem. The most common pathogens of infections among gram-negative bacteria are representatives of the Enterobacteriaceae family. Pectobacterium are gram-negative phytopathogenic bacteria belonging to the Enterobacteriaceae family.The purpose of the study is to develop methods for the identification of phytopathogenic bacteria. At the capacity of test components of developed identification algorithm, we used the data presented in the reference «Bergey’s Manual of Systematics of Archaea and Bacteria». research parameters and for selection of Model microorganisms bacteriological tests were reference strains of Pectobacterium carotovorum B-3455 obtained from the All-Russian collection of microorganisms and Pectobacterium carotovorum 333 from the collection of NRCEM Museum of FSBEI HE Ulyanovsk SAU named after P.А. Stolypin. From 50 samples of phytosanitary control and environmental objects, 5 strains were classified as Pectobacterium carotovorum spp. carotovorum.
Tillage techniques in grass crop rotations in Western Kazakhstan
Authors: Bulekova Akzhbek , Bulekov Tulegen , Limanskaya Valentina , Gumarova Zhannar , Kozhakhmetova Ainat
Published: February 2024

The transition to new technologies is predetermined by global and domestic scientific and production experience and general trends in the development of agriculture. The basis of grass crop rotations is the general biological principle of the different effects of perennial grasses on the soil. To the problem of forage production for the conditions of the arid steppe of Western Kazakhstan with an annual rainfall of 250-300 mm, a method of using forage crops based on grass crop rotation is proposed. Periodic change of different crops in crop rotation plays a positive phytosanitary role in clearing the soil of weeds. The article discusses three types of soil cultivation techniques based on the principles of sustainable production of grain crops and stabilization of soil fertility in the conditions of Western Kazakhstan. The research was carried out on the basis of the Ural Agricultural Experimental Station LLP. The purpose of the research is to develop methods of soil cultivation in grass crop rotations for the accumulation, conservation and rational use of soil moisture in resource-saving technologies for cultivating basic field crops, ensuring the preservation of soil fertility, improving the phytosanitary condition of crops in the dry steppe zone of Western Kazakhstan. The objective of the research is to study the influence of methods for processing turf of perennial grasses in the structure of crop rotations in order to stabilize soil fertility and the phytosanitary condition of crops. Three types of processing were used in the studies: flat cutter, slotting + cultivation, cultivation. Grass crop rotation was sown over a layer of perennial grasses and included the following forage crops: sorghum, corn and millet. The best results in terms of yield were observed based on the joint interaction of technologies for factor B (slotting + cultivation).
Assessment of herbicide application efficiency on oilseed flax in Penza region of the Russian Federation
Authors: Tarakanov Rashit , Chebanenko Svetlana , Beloshapkina Olga , Dzhalilov Fevzi , Savoskina Olga
Published: February 2024

Oilseed flax at the beginning of vegetation is strongly suppressed by weeds, so the choice of optimal and effective herbicide is one of the factors of high productivity of its crops. In this work, the efficiency of application of tank mixtures of seven herbicides on oilseed flax varieties Vnimk 620 and Itil was evaluated in the production experiment in the farm in Penza region. Biological efficiency of the preparations and economic efficiency of their application in the conditions of the region were evaluated. When using a tank mixture of Gerbitoks-L, WSC + Kvikstep, EOO, almost complete destruction of dicotyledonous and cereal weeds (90.94%) in the crops of both varieties of flax was achieved and economic profitability of 55.9% was ensured. For effective control of weeds in oilseed flax crops under conditions of Penza region it is recommended to use tank mixture of herbicides Gerbitoks-L, WSC + Kvikstep, EOO at a rate of 1.5+0.8 l/ha.
A comparative analysis of traditional meat processing methods
Authors: Dissanayake Kasun , Rifky Mohamed , Nurmukhamedov Khabibulla , Makhmayorov Jasur , Abdullayev Bakhodir , Farmanov Jasur , Samadiy Murodjon
Published: February 2024

This comparative analysis examines traditional meat preservation techniques, including drying, curing, fermentation, smoking, fat preservation, air drying, fermented fish sauce, pickling and traditional sausage making. Rooted in different cultures, these methods use specific processes and ingredients to preserve meat, enhance flavour and extend shelf life. Some different variations and adaptations showcase techniques such as marinating, braising, and incorporating herbs or probiotics. Studies highlight advances in reducing salt and nitrite levels during pickling, improving brine handling methods, and optimizing smoking techniques for safety. Factors affecting preservation include the microbial community in fermented cured meats, temperature control during smoking and moisture content during air drying. Recent research findings observed that fermentation-enhanced sausage flavour and certain microorganisms declined histamine levels in fish sauce. New technologies and traditional methods combined facilitate conservation, nutrition, and the sensory quality of meat.
Kommentar zu: Zöliakie bei Kindern:
Nährstoffdefiziten unter glutenfreier Diät
entgegenwirken
Authors: Zopf Yurdagül
Published: February 2024

Zum Zeitpunkt der Diagnosestellung einer Zöliakie weisen viele Patienten
zahlreiche Defizite an Mikronährstoffen auf. Am häufigsten findet
man einen Mangel an Eisen, Zink, Magnesium, Folsäure und den Vitaminen A,
B12, B6 und D. Nach Einführen einer glutenfreien Diät (GFD) und
damit einhergehend der Regeneration der Dünndarmschleimhaut und somit der
verbesserten Nährstoffaufnahme, geht in der Regel auch eine Verbesserung der
Mikronährstoffsituation einher. Trotz Einhaltung der GFD können im
Verlauf Mikronährstoffmangel vorliegen, die bei entsprechender Symptomatik
ausgeglichen werden sollten. Der Nährstoffmangel kann durch eine
persistierende oder neu auftretende entzündlich bedingte Malabsorption
verursacht sein oder diätetische Ursachen haben. Glutenhaltige Lebensmittel
stellen wichtige Quellen für die B-Vitamine, Eisen und Proteine dar. Eine
Elimination kann daher zur Veränderung der Nährstoffaufnahme und
Mangelerscheinungen führen, denn glutenfreie Ersatzprodukte weisen
häufig einen geringeren Proteingehalt aber deutlich höheren Fett-
und Salzgehalt sowie einen geringeren Gehalt an Folsäure, Eisen und
Mineralstoffen auf 1.
Editorial
Authors: Stock Philippe
Published: February 2024

Liebe Kolleginnen und Kollegen, liebe Freundinnen und Freunde der GPP,

es ist wieder soweit: Sie halten das GPP Heft für die 45. Jahrestagung der
Gesellschaft für Pädiatrische Pneumologie in Bochum in den
Händen.
Staging and Management of Cervical Cancer at the Colposcopy Clinic of Bangabandhu Sheikh Sheikh Mujib Medical University (BSMMU), Bangladesh
Authors: Nessa Ashrafun , Islam Thrina , Noor-E-Ferdousi Noor-E-Ferdousi , Sultana Anjuman , Khan Kamrul Hasan , Rashid Harun ur
Published: February 2024

Cervical cancer (CC) ranks as the second most common cancer among women in Bangladesh. Unfortunately, due to late-stage diagnosis and inadequate treatment facilities, the mortality rate remains high. The stage at which CC is diagnosed plays a crucial role in predicting a woman's survival. This study aimed to determine the staging patterns of CC at presentation in the colposcopy clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU) and the subsequent management provided to these women. This retrospective study was conducted at the BSMMU colposcopy clinic from January 2019 to June 2020. It included CC cases with known staging, spanning from January 2016 to June 2019. Data were collected from the colposcopy registry book, telephone interviews, and face-to-face discussions during follow-up appointments. The mean age of women diagnosed with CC was 48.59 years (±2 standard deviations). Among the 523 women studied, 107 (20.5%) were diagnosed at stage I, 124 (23.7%) at stage IIA, 240 (45.9%) at stage IIB, while the remaining 52 (9.90%) were diagnosed with Stage III and IV disease. Within the study population, 39 (7.5%) women underwent radical hysterectomy alone, 110 (21.00%) underwent radical hysterectomy followed by adjuvant therapy, and 184 (35.14%) received primary radiotherapy or concurrent chemoradiation. A significant portion of CC cases presented at an early stage, underscoring the importance of an effective screening program to prevent advanced-stage disease and enhance early detection rates. Establishing a patient navigation system immediately after diagnosis is crucial to prevent the loss of follow-up and ensure timely treatment. It is imperative to enhance the healthcare system's capacity to ensure timely treatment for cancer patients.
The moderating role of perceived brand globalness on the effects of consumers’ attitude during periods of political controversies: three interconnected studies following marketing analytics’ best practices
Authors: Luna-Cortes Gonzalo , López-Bonilla Luis Miguel , López-Bonilla Jesús Manuel
Published: February 2024

The purpose of this research is to test the moderating role of perceived brand globalness (PBG) on consumer unfavourable attitudes and buying intention towards brands associated with a conflicting political belief. Three studies were conducted. Study 1 (N = 228) examines the effect of a brand being associated with a conflicting political belief on attitude and buying intention. Study 2 (N = 212) tests the moderating role of PBG among these relationships. Study 3 (N = 126) tests the moderating role of PBG for a service brand and adds the mediating role of self-congruity. We followed marketing analytics best practices to examine causal effects of manipulated stimuli. We also examined the psychometric characteristics of the data-collection tool and tested direct relationships between variables. Additionally, we used percentile bootstrap confidence intervals, with PROCESS-Macro, to test mediating effects in the theoretical model. The studies include moderating analyses and analysis of variance. The results show that the association of a brand with a conflicting political belief negatively influences perceived self-congruity, which leads to an unfavourable attitude and, in turn, to a lower buying intention. Presenting a brand as global mitigates such unfavourable effects. The moderating effect of PBG is confirmed for a tangible product and for a service brand.
“Terrestrial Verses” on the borderline: an interdisciplinary decolonial reading of Forugh Farrokhzad and Frida Kahlo
Authors: Moosavi Seyedeh Zahra
Published: February 2024

This article studies the social and historical underpinnings of Forugh Farrokhzad’s poem “Terrestrial Verses” (1962) and her documentary film The House is Black (1962) in light of Frida Kahlo’s painting, Self-Portrait on the Borderline Between Mexico and the United States (1932). I argue that this unlikely comparison—between neocolonial Mexico and postcolonial Iran—helps articulate a decolonial paradigm in Farrokhzad’s poetry that is often subdued in Persian literary studies. Few scholars have approached Frida Kahlo and Forugh Farrokhzad’s works from a post- or decolonial point of view, and almost no one has compared these two artists. Nevertheless, hitherto unseen aspects of their work address their politics, sense of worldliness, visions of decolonization, and dismantling of the colonial residues in their respective cultural contexts through their art and artistic expressions. In terms of Farrokhzad’s poetry, the history of medicine and public health in Iran is of high importance as I make my case. This interdisciplinary and comparative reading results in a new understanding of the epidemic of leprosy as an unintended consequence of the “colonial matrix of power” in Iran during WWI.
The effect of hydrogenation on the electrophysics and magnetic characteristics of dysprosium
Authors: Sokolenko V. I. , Chupikov A. O. , Pylypenko M. M. , Lazareva M. B. , Roskoshna O. Yu.
Published: February 2024

The effect of hydrogenation from the gas phase on the change in the character of the temperature dependence of the electrical resistivity ρ(T) in the range of 77–300 K and the temperatures of phase magnetic transformations (Curie temperature TC and Néel temperature TN) of dysprosium was studied. It follows from the experimental data and their analysis that, within the framework of the indirect exchange ideas, the decreases in TC, TN and the contribution to ρ(T) related to electron scattering in the paramagnetic phase are interrelated. It has been suggested that hydrogenation effects may be related to changes in microscopic parameters: a decrease in the density of states at the Fermi level, an increase in the Fermi energy, and a decrease in the effective mass of carriers and the s-f exchange parameter.
Temperature effect and Rashba effect of polaron in a parabolic quantum well
Authors: Shan Shu-Ping
Published: February 2024

Using Tokuda’s improved linear combination operator method and variational technique, the expression of the polaron effective mass in an parabolic quantum well is derived. Due to the spin-orbit interaction, the effective mass of polaron splits into two branches. The dependence of effective mass on temperature and mean number phonons is discussed by numerical calculation. The effective mass of polaron is an increasing function of temperature and mean number phonons. The absolute value of total spin splitting effective mass increases with the increase in temperature and spin-orbit coupling parameter, and decreases with the increase in velocity. Due to the heavy hole characteristic, the spin splitting effective mass is negative.
Modeling Fermi energy, free-carrier density, and resistivity in degenerate n-Ge
Authors: Abenante Luigi
Published: February 2024

A new expression for Fermi energy vs doping is derived using the standard model for free carriers in n-type semiconductors. The new expression is composed of the Fermi energy in non-degenerate semiconductors, a doping function for bandgap narrowing (BGN), and an adjustable energy variation. In non-degenerate semiconductors, the new expression is equivalent to the standard Boltzmann expression. Calculated curves of Fermi energy are assigned in the Fermi–Dirac expression for the donor ionization ratio, and reported data of electron density and resistivity measured in heavily doped n-Ge layers are fitted. Five reported doping functions for BGN are used. One of the BGN functions allows modeling frustrated incomplete ionization. Another allows modeling bandgap widening.
Wire texture C-axis distribution of strontium ferrite/PA-12 extruded filament
Authors: Espinosa-Rodriguez Gabriela , Arigbabowo Oluwasola , Alvarado Jonathan , Tate Jitendra , Geerts Wilhelmus J.
Published: February 2024

The magnetic anisotropy of strontium ferrite (SF)/PA12 filament, a popular hard magnetic ferrimagnetic composites that is used for 3D-printing of permanent magnets, is studied by vibrating sample magnetometry. The studied filaments have a composition of SF/PA-12 thermoplastic composite with a 40% wt.  ratio of SF. SF particles are non-spherical platelets with an average diameter of 1.3 um and a diameter to thickness ratio of 3. Filaments are produced by a twin-screw extruder and have a diameter of 1.5 mm. SEM images show that the SF particles are homogeneously distributed through the filament. VSM measurements on different parts of the filaments show that the outer part of the cylindrical filament has a higher anisotropy, and the core is mostly isotropic. This conclusion is consistent with computational work by others which suggest that particle alignment predominantly takes place near the walls of the extruder die where shear flow is maximum. Additional hysteresis curve measurement of the outer cylindrical part of the filament parallel to the r and ϕ directions indicates that the squareness of the hysteresis curve (S) is larger in the r-direction. This indicates that the outer surface of the filament has a strong easy axis in the r-direction. We conclude that the SF platelets line up parallel to the walls of the extrusion die.
Variable expression of
MECP2, CDKL5,
and
FMR1
in the human brain: Implications for gene restorative therapies
Authors: Zito Antonino , Lee Jeannie T.
Published: February 2024

MECP2, CDKL5,
and
FMR1
are three X-linked neurodevelopmental genes associated with Rett, CDKL5-, and fragile-X syndrome, respectively. These syndromes are characterized by distinct constellations of severe cognitive and neurobehavioral anomalies, reflecting the broad but unique expression patterns of each of the genes in the brain. As these disorders are not thought to be neurodegenerative and may be reversible, a major goal has been to restore expression of the functional proteins in the patient’s brain. Strategies have included gene therapy, gene editing, and selective Xi-reactivation methodologies. However, tissue penetration and overall delivery to various regions of the brain remain challenging for each strategy. Thus, gaining insights into how much restoration would be required and what regions/cell types in the brain must be targeted for meaningful physiological improvement would be valuable. As a step toward addressing these questions, here we perform a meta-analysis of single-cell transcriptomics data from the human brain across multiple developmental stages, in various brain regions, and in multiple donors. We observe a substantial degree of expression variability for
MECP2
,
CDKL5
, and
FMR1
not only across cell types but also between donors. The wide range of expression may help define a therapeutic window, with the low end delineating a minimum level required to restore physiological function and the high end informing toxicology margin. Finally, the inter-cellular and inter-individual variability enable identification of co-varying genes and will facilitate future identification of biomarkers.
Perturbative diffraction methods resolve a conformational switch that facilitates a two-step enzymatic mechanism
Authors: Greisman Jack B. , Dalton Kevin M. , Brookner Dennis E. , Klureza Margaret A. , Sheehan Candice J. , Kim In-Sik , Henning Robert W. , Russi Silvia , Hekstra Doeke R.
Published: February 2024

Enzymes catalyze biochemical reactions through precise positioning of substrates, cofactors, and amino acids to modulate the transition-state free energy. However, the role of conformational dynamics remains poorly understood due to poor experimental access. This shortcoming is evident with
Escherichia coli
dihydrofolate reductase (DHFR), a model system for the role of protein dynamics in catalysis, for which it is unknown how the enzyme regulates the different active site environments required to facilitate proton and hydride transfer. Here, we describe ligand-, temperature-, and electric-field-based perturbations during X-ray diffraction experiments to map the conformational dynamics of the Michaelis complex of DHFR. We resolve coupled global and local motions and find that these motions are engaged by the protonated substrate to promote efficient catalysis. This result suggests a fundamental design principle for multistep enzymes in which pre-existing dynamics enable intermediates to drive rapid electrostatic reorganization to facilitate subsequent chemical steps.
‘But we’re among peers!’
Authors: Veret Thomas
Published: February 2024

Focusing on French social science and humanities journals, this article examines the digital communication
surrounding the submission of articles by scholars based in Africa. Using Cameron’s concept of verbal hygiene ([1995] 2012), I analyze the case of negative reactions from editors triggered by
stylistic and rhetorical features related to politeness. Through a detailed case study, the paper shows that such negative
reactions involve semiotic processes of linguistic and social differentiation that articulate the moralized persona of the author
and the scientific value of his/her work. However, editors’ verbal hygiene attitudes are also intertwined with political concerns
aimed at promoting the inclusion of scholars from the Global South. In that context, the analysis reveals a complex interplay
between the desire for openness and structural patterns of exclusion that enact long-standing hierarchies in knowledge production.
Drawing on Inoue’s (2003) theory of the listening subject, I argue that this paradox
arises from the reader’s particular position within the globalized academic landscape and from the power structures inherent in
the circulation of texts between African and French academic contexts.
On uniqueness for half-wave maps in dimension 𝑑≥3
Authors: Eyeson Eugene , Reyes Farina Silvino , Schikorra Armin
Published: February 2024

Extending an argument by Shatah and Struwe [Int. Math. Res. Not. 11 (2002), pp. 555–571] we obtain uniqueness for solutions of the half-wave map equation in dimension

d
≥
3

d \geq 3

in the natural energy class.
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for gastric cancer with intraoperative detection of limited peritoneal metastasis: a Phase II study of CLASS-05 trial
Authors: Lin Tian , Chen Xinhua , Xu Zhijun , Hu Yanfeng , Liu Hao , Yu Jiang , Li Guoxin
Published: February 2024

Background

Systemic chemotherapy for gastric cancer with peritoneal metastasis has limited clinical benefit; for those with intraoperative detection of occult peritoneal metastasis, cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is an alternative treatment. However, the feasibility and effects of this modality and criteria for selecting suitable groups remain unclear. This study aimed to explore the safety and efficacy of laparoscopic cytoreductive surgery (L-CRS) followed by HIPEC in gastric cancer with limited peritoneal metastasis, and this study also aimed to determine the optimized cut-off of the peritoneal cancer index.

Methods

Between March 2017 and November 2019, patients diagnosed with gastric cancer peritoneal metastases by using laparoscopy and the Sugarbaker peritoneal cancer index of ≤12 were eligible for inclusion. All patients received L-CRS (including gastrectomy with D2 lymph node dissection) and resection of visible peritoneal metastasis, followed by post-operative HIPEC, and systemic chemotherapy. The primary end points were median progression-free survival and median survival time, and the secondary outcomes were morbidity and mortality within 30 days after surgery.

Results

Thirty patients were eligible for analysis, of whom 19 (63.3%) were female, and the overall mean age was 53.0 years. The post-operative morbidity was 20% and the severe complication rate was 10%. The median survival time was 27.0 months with a 2-year overall survival rate of 52.3% and median progression-free survival was 14.0 months with a 2-year progression-free survival of 30.4%.

Conclusions

L-CRS followed by HIPEC can be safely performed for gastric cancer with limited peritoneal metastasis and potential survival benefits.
Is there a route for metachronous inguinal lymph node in colonic cancer? A case report
Authors: Neirouz Kammoun , Mehdi Trabelsi Mohamed , Mohamed Guelbi , Sohaib Messaoudi , Annouar Oueslati , Mehdi Khalfallah , Ramzi Nouira
Published: February 2024

As the inguinal lymph nodes do not serve as the primary route for the lymphatic drainage of the colon, inguinal metastasis from colorectal carcinomas is considered an unusual finding, especially in the 2nd year follow-up. A 76-year-old male patient, operated on for non-metastatic right colic adenocarcinoma, consulted 2 years after for a right inguinal swelling. A biopsy was performed. Unexpectedly, it showed an adenocarcinoma metastasis in favor of a colonic origin. There was no relapse of the disease. The pathological examination of the resected inguinal lymph node confirmed malignant cells from a colonic origin. As the positron emission tomography scan showed no other tumoral localizations, a multidisciplinary discussion ensued, culminating in the choice of chemotherapy for optimal pathological response. This case highlights the fact that colic drainage may encounter inguinal lymph nodes and thus inguinal groin metastasis could exceptionally have been seen in colonic carcinomas.
Devising the items
Authors: Streiner David L. , Norman Geoffrey R. , Cairney John
Published: February 2024

This chapter discusses various sources for the items that make up a health measurement scale (e.g. existing item banks, patient interviews, research, clinical judgement, expert opinion, and theory). It then covers ways of ensuring content validity of the resulting items. This involves assessing whether all domains are covered and whether each item maps onto one and only one domain. The chapter covers both subjective and objective ways of doing this. It reviews the arguments for and against disease-specific scales as opposed to generic ones. Finally, it discusses the issues that arise when a scale is translated from one language to another.
Selecting the items
Authors: Streiner David L. , Norman Geoffrey R. , Cairney John
Published: February 2024

Not all of the items that have been generated will prove to be useful. This chapter discusses the criteria of a good item, such as its reading level, lack of ambiguity, asking only a single question, freedom from jargon, being worded in a positive direction, and length. Another consideration is the distribution of responses, whether all response alternatives have been used by at least some of the respondents, and when items with very low endorsement frequencies may actually be useful. It also discusses the homogeneity of the scale and the various ways of measuring it (e.g. KR-20, split-halves, and Cronbach’s alpha). Finally, it discusses when homogeneity is and is not important, and which statistical tests should not be used when homogeneity is not required.
Generalizability theory
Authors: Streiner David L. , Norman Geoffrey R. , Cairney John
Published: February 2024

This chapter is a detailed review of generalizability theory (G theory), an extension of classical reliability theory originally devised by Cronbach. The basic concept is that any measurement contains multiple sources of error, and through the use of G theory these various sources can be calculated in a single study. This permits the researcher to examine the relative magnitude of different sources of error and the relation among them. The power of the method rests in its ability to use these estimates to devise optimal strategies for distributing observations. That is, G theory can be used to determine how a fixed number of observations should be distributed across raters, occasions, or cases to optimize reliability.
Reporting test results
Authors: Streiner David L. , Norman Geoffrey R. , Cairney John
Published: February 2024

Journals are becoming increasingly more stringent in their requirements for what must be reported in articles about the psychometric properties of scales. This chapter reviews three of the most commonly used guidelines : the Standards for Educational and Psychological Testing, the STARD initiative (Standards for Reporting of Diagnostic Accuracy), and the Guidelines for Reporting Reliability and Agreement Studies (GRRAS). It abstracts portions of these guidelines that are most relevant for scales used in research settings. These cover the reporting of test development, reliability, and validity. The chapter also has a flow chart, adapted from STARD, which should be included when submitting a manuscript about scale development to a journal.
Dermatological problems
Authors: Currow David , Clark Katherine , Kleinig Paul
Published: February 2024

Although relatively rare, severe, systemic skin conditions can affect people with life-limiting illnesses. These are most often iatrogenic. Late in life, the risk of mortality increases significantly. Ensuring early recognition of serious dermatological conditions maximizes the time to discuss with the person who has the life-limiting illness and their family how aggressively to support the person at that time. Less life-threatening presentations of systemic dermatological problems still create significant challenges in symptom control, given the challenges of pain and dressings (where appropriate).
Gastrointestinal disorders
Authors: Currow David , Clark Katherine , Kleinig Paul
Published: February 2024

Managing gastrointestinal disorders in supportive and palliative care requires careful attention to the person’s history, accompanied by a careful physical examination. Symptoms are often unpleasant for the person and for those looking after them. As non-invasive interventions multiply, the currency of clinical practice and the knowledge of local resources become paramount in considering the options that are reasonably available even in someone who is frail. The parallel process of managing symptoms while considering any definitive course of action is especially important for people with symptoms from gastrointestinal dysfunction.