bluuebunny/crossref_metadata_2025 huggingface dataset:
Podocalyxin‐like protein promotes gastric cancer progression through interacting with RUN and FYVE domain containing 1 protein
Authors: Zhi Qiaoming , Chen Huo , Liu Fei , Han Ye , Wan Daiwei , Xu Zhihua , Kuang Yuting , Zhou Jin
Published: November 2018

Podocalyxin‐like protein (PODXL), a transmembrane glycoprotein with anti‐adhesive properties, is associated with an aggressive tumor phenotype and poor prognosis of several cancers. To elucidate the biological significance of PODXL and its molecular mechanism in gastric cancer (GC), we investigated the expression of PODXL in GC samples and assessed its effects on biological behaviors and the related signaling pathways in vitro and in vivo. Moreover, the possible and closely interacted partners of PODXL were identified. Our data showed that the protein or mRNA level of PODXL was significantly upregulated in tissues or serum of GC patients compared with normal‐appearing tissues (NAT) or those of healthy volunteers. Overall survival (OS) curves showed that patients with high PODXL levels in tissues or serum had a worse 5‐year OS. In vitro, restoring PODXL expression promoted tumor progression by increasing cell proliferation, colony formation, wound healing, migration and invasion, as well as suppressing the apoptosis. Furthermore, the PI3K/AKT, NF‐κB and MAPK/ERK signaling pathways were activated. There was a significant positive correlation between PODXL and RUN and FYVE domain containing 1 (RUFY1) expression in tissues or serum. Subsequent mass spectrometry analysis, co‐immunoprecipitation assays and western blot analysis identified PODXL/RUFY1 complexes in GC cells, and silencing RUFY1 expression in GC cells significantly attenuated PODXL‐induced phenotypes and their underlying signaling pathways. Our results suggested that PODXL promoted GC progression via a RUFY1‐dependent signaling mechanism. New GC therapeutic opportunities through PODXL and targeting the PODXL/RUFY1 complex might improve cancer therapy.
Role of the Embodied Cognition Process in Perspective‐Taking Ability During Childhood
Authors: Hirai Masahiro , Muramatsu Yukako , Nakamura Miho
Published: November 2018

This study examined developmental changes in Level‐2 visual perspective taking (VPT2) in 90 children aged 4–12 years and tested the role of their ability to mentally simulate changes to their bodily locations (self‐motion imagery; SMI). Performance of a mental toy rotation task and a self‐motion (SM) task (changing location of children) was superior to that of VPT2 and SMI tasks. Task performance of SMI was better than that of VPT2 before 10;0 (years;months). Furthermore, egocentric responses in VPT2 and SMI tasks were significantly more frequent than those in the mental rotation and SM tasks before 10;3. These findings suggest the involvement of embodied cognitive processes in perspective taking and the advantage of utilizing bodily information by age 10.
Impact of hepatic artery size mismatch between donor and recipient on outcomes after living‐donor liver transplantation using the right lobe
Authors: Harada Noboru , Yoshizumi Tomoharu , Uchiyama Hideaki , Soejima Yuji , Ikegami Toru , Itoh Shinji
Published: November 2018

Introduction

The aim of this study was to evaluate the effect of hepatic artery (HA) size mismatch anastomosis on outcomes after living‐donor liver transplantation (LDLT).

Materials and methods

After excluding 128 patients with the exclusion criteria among 233 LDLTs using the right lobe, 104 LDLT patients were divided into two groups: donor HA diameter that was greater than or equal to the recipient HA diameter (D ≥ R group; n = 79), and donor HA diameter that was smaller than the recipient HA diameter (D < R group; n = 25).

Results

Hepatic artery‐related complications occurred in only one patient (HA thrombosis; 1.0%) who was in the D < R group. The reconstructed HA flow in the D ≥ R group was significantly greater than that in the D < R group (P = 0.015). There was a higher incidence of anastomotic biliary stricture in the D < R group (32.0%) compared with the D ≥ R group (13.9%, P = 0.022) after LDLT. A multivariate analysis with Cox regression revealed that the HA anastomosis of the D < R group and hepaticojejunostomy were significant independent risk factors for postoperative anastomotic biliary stenosis.

Conclusions

Hepatic artery anastomosis with a donor HA diameter smaller than that of the recipient HA might be an independent risk factor for postoperative biliary stenosis after LDLT using the right lobe.
Mannosylerythritol lipids inhibit melanogenesis via suppressing ERK‐CREB‐MiTF‐tyrosinase signalling in normal human melanocytes and a three‐dimensional human skin equivalent
Authors: Bae Il‐Hong , Lee Eun Soo , Yoo Jae Won , Lee Sung Hoon , Ko Jae Young , Kim Yong Jin , Lee Tae Ryong , Kim Dae‐Yong , Lee Chang Seok
Published: November 2018

Hyperpigmentation is caused by excessive production of melanin in melanocytes. Mannosylerythritol lipids (MELs) are glycolipid biosurfactants that are abundantly produced by yeasts and used commercially in cosmetics. However, the potential depigmenting efficacy of MELs has not been evaluated. In this study, the depigmentary effect of MELs was tested in primary normal human melanocytes (NHMs), α‐melanocyte‐stimulating hormone (MSH)‐stimulated B16 cells (murine melanoma cells) and a human skin equivalent (MelanoDerm) using photography, Fontana‐Masson (F&M) staining and two‐photon microscopy. Mannosylerythritol lipids significantly decreased the melanin contents in NHMs and α‐MSH‐stimulated B16 cells. Consistent with these findings, MELs treatment had a clear whitening effect in a human skin equivalent, brightening the tissue colour and reducing the melanin content. The molecular mechanism underlying the anti‐melanogenic effect of MELs treatment was examined by real‐time PCR and Western blotting. Mechanistically, MELs clearly suppressed the gene expression levels of representative melanogenic enzymes, including tyrosinase, Tyrp‐1 and Tyrp‐2, by inhibiting the ERK/CREB/MiTF signalling pathway in NHMs. This work demonstrates for the first time that MELs exert whitening effects on human melanocytes and skin equivalent. Thus, we suggest that MELs could be developed as a potent anti‐melanogenic agent for effective whitening, beyond their use as a biosurfactant in cosmetics.
More equal than others: Assessing economic and citizen groups' access across policymaking venues
Authors: Weiler Florian , Eichenberger Steven , Mach André , Varone Frédéric
Published: November 2018

This study assesses whether economic interest groups (business associations and trade unions) enjoy better access to the policymaking process than citizen groups. It compares the interest group population in Switzerland with those sets of groups present in the administrative and legislative venues. The study devises an aggregate measure of access to policymaking as a whole, which weights access according to different venues' importance. It theorizes the granting of access as a sequential process. Policymakers first decide whether to grant any access at all (selection stage) and then decide on the amount of access (allocation stage). Empirical evidence shows that policymakers do not discriminate between economic and citizen groups at the selection stage, but that they subsequently grant more access to economic groups. These findings qualify existing research, which interprets economic groups' superior access as the resilience of neo‐corporatism, while also questioning the pluralizing effect of multiple policymaking venues.
Correlates of cognitive impairment in patients with chronic kidney failure on haemodialysis: Systematic review and meta‐analysis
Authors: Oh HyunSoo , Mo JinA , Seo WhaSook
Published: November 2018

Aim

To review and identify correlates of cognitive impairment in patients with chronic kidney failure (CKF) on haemodialysis.

Background

The literature is consistent with regard to the high prevalence of cognitive impairment among patients with CKF on haemodialysis and its dependence on multidimensional risk factors.

Design

Systematic review and meta‐analysis based on Cochrane Handbook and PRISMA.

Data sources

Electronic searches of the MEDLINE, EMBASE, Cochrane Library databases and major Korean databases were used. Only original research that assessed correlates of cognitive impairment in patients with CKF on haemodialysis and published between 2004–2016 in English or Korean were included.

Review methods

Studies were selected according to the PICOS: Population (chronic kidney failure patients with cognitive impairment on haemodialysis); Intervention (not applicable); Comparison (healthy controls or patients with chronic kidney failure on haemodialysis without cognitive impairment); Outcome (cognitive impairment); and Study design (primarily nonexperimental correlational studies and studies with experimental, quasi‐experimental, or pre–post cohort designs). Q‐test and I2 index were used to examine study homogeneity.

Results

A total of 39 studies were finally included. Age, gender, stroke history, difficulties in activities of daily life, haemoglobin levels, pain, sleep difficulties, and depression were found to be significant correlates of cognitive impairment.

Conclusions

Nurses should be aware that the risk of cognitive impairment in patients with CKF on haemodialysis can be significantly higher for elders, women and in patients with a stroke, greater difficulties in activities of daily living, lower haemoglobin concentrations, higher pain levels, sleep difficulties, or depression.
MiR‐520b promotes the progression of non‐small cell lung cancer through activating Hedgehog pathway
Authors: Liu Xiaoming , Liu Jichun , Zhang Xuekang , Tong Yuben , Gan Xin
Published: November 2018

Although the non‐small cell lung cancer (NSCLC) is one of the most malignant tumours worldwide, the mechanisms controlling NSCLC tumourigenesis remain unclear. Here, we find that the expression of miR‐520b is up‐regulated in NSCLC samples. Further studies have revealed that miR‐520b promotes the proliferation and metastasis of NSCLC cells. In addition, miR‐520b activates Hedgehog (Hh) pathway. Inhibitor of Hh pathway could relieve the oncogenic effect of miR‐520b upon NSCLC cells. Mechanistically, we demonstrate that miR‐520b directly targets SPOP 3′‐UTR and decreases SPOP expression, culminating in GLI2/3 stabilization and Hh pathway hyperactivation. Collectively, our findings unveil that miR‐520b promotes NSCLC tumourigenesis through SPOP‐GLI2/3 axis and provide miR‐520b as a potential diagnostic biomarker and therapeutic target for NSCLC.
Cost‐of‐illness of melanoma in Europe – a systematic review of the published literature
Authors: Krensel M. , Schäfer I. , Augustin M.
Published: November 2018

Malignant melanoma accounts for the vast majority of skin cancer deaths. Primary prevention is used to increase knowledge about skin cancer and set incentives for a change in behaviour, which leads to a decrease in cases. Primary prevention may be cost‐effective or even cost saving. Cost‐of‐illness (COI) studies provide information on such potential savings. The purpose of this study is to give an overview on COI studies in European countries and to compare the COI in total and by cost categories. The results can be used to model potential cost savings from prevention. We conducted a systematic literature research in PubMed using thePRISMAchecklist. All costs were converted into Euro and adjusted for the reference year 2012. For the ranking of countries according to their COI, all costs were adjusted for the purchasing power parity. All studies focusing on stageIII–IVmelanoma include information on hospital, hospice, and outpatient treatment. Costs for the treatment of advanced melanoma range between € 2972 in Italy and € 17 408 in Sweden after adjusting for purchasing power parity. Most studies on stage I–IVmelanoma include costs of hospitalization, outpatient treatment and general practitioner consultation. Direct costs range from € 923 in Sweden to € 9829 in Denmark. Three articles also include information on indirect costs. Mortality costs vary between € 3511 in Sweden and € 20 408 in England, morbidity costs between € 103 in Sweden and € 4550 in England. We showed that costs for the treatment of skin cancer are moderately high in the included countries. Since after publication of the articles new costly drugs were approved in Europe, treatment costs of melanoma in Europe may be expected to have risen in the last few years, which means that there is a high expectable potential for prevention programmes to become cost‐effective or even cost saving.
Multihazard simulation for coastal flood mapping: Bathtub versus numerical modelling in an open estuary, Eastern Canada
Authors: Didier David , Baudry Jérémy , Bernatchez Pascal , Dumont Dany , Sadegh Mojtaba , Bismuth Eliott , Bandet Marion , Dugas Sebastien , Sévigny Caroline
Published: November 2018

Coastlines along the St. Lawrence Estuary and Gulf, Eastern Canada, are under increasing risk of flooding due to sea level rise and sea ice shrinking. Efficient and validated regional‐scale coastal flood mapping approaches that include storm surges and waves are hence required to better prepare for the increased hazard. This paper compares and validates two different flood mapping methods: numerical flood simulations using XBeach and bathtub mapping based on total water levels, forced with multihazard scenarios of compound wave and water level events. XBeach is validated with hydrodynamic measurements. Simulations of a historical storm event are performed and validated against observed flood data over a ~25 km long coastline using multiple fit metrics. XBeach and the bathtub method correctly predict flooded areas (66 and 78%, respectively), but the latter overpredicts the flood extent by 36%. XBeach is a slightly more robust flood mapping approach with a fit of 51% against 48% for the bathtub maps. Deeper floodwater by ~0.5 m is expected with the bathtub approach, and more buildings are vulnerable to a 100‐year flood level. For coastal management at regional‐scale, despite similar flood extents with both flood mapping approaches, results suggest that numerical simulation with XBeach outperforms bathtub flood mapping.
Enhancing Parenting Effectiveness, Fathers' Involvement, Couple Relationship Quality, and Children's Development: Breaking Down Silos in Family Policy Making and Service Delivery
Authors: Cowan Carolyn Pape , Cowan Philip A.
Published: November 2018

In this article, we examine family‐based interventions designed to increase parenting effectiveness, fathers' positive involvement, and couple relationship quality, all with the goal of enhancing children's development. We focus on the fact that government funding policies, service delivery systems, and research evaluations of interventions to benefit children and families typically operate in separate silos. We provide a theoretical model, along with empirical evidence, to argue that a more integrated, collaborative perspective is likely to produce more optimal outcomes for parents and children than current siloed attempts to improve child and family well‐being. We discuss some of the obstacles to using evidence to guide policy decisions. We offer suggestions for policy makers and service providers in an attempt to describe a more integrated approach to supporting family well‐being, and to encourage the increased use of systematic data in making decisions about how to allocate scarce resources for family support.
Helicobacter pylori and low‐dose aspirin ulcer risk: A meta‐analysis
Authors: Sarri Gino L , Grigg Sam E , Yeomans Neville D
Published: November 2018

Background and Aim

Owing to wide‐spread use, low‐dose aspirin (LDA) produces a substantial amount of peptic ulcer disease. Current guidelines are ambivalent about the need for Helicobacter pylori eradication to protect against LDA ulcers. This study aimed to determine, through meta‐analysis, if (and by how much) infection alters the baseline risk of peptic ulcers during LDA therapy.

Methods

Literature screening was performed in MEDLINE and EMBASE from inception to May 2018. Original studies reporting prevalence or incidence of uncomplicated ulcers in LDA users were included. Ulcer endpoints needed to be specified separately, according to H. pylori infection status. Meta‐analysis was performed in MIX 2.0 Pro.

Results

Ten cross‐sectional studies and seven randomized controlled trials were included (n = 5964). The pooled odds ratios with 95% confidence intervals (CI) for the risk of LDA ulcers in H. pylori‐positive versus H. pylori‐negative individuals were 1.68 (95%CI 1.40–2.02) and 1.65 (95%CI 1.29–2.08) under fixed‐effects and random‐effects models, respectively. Heterogeneity among studies was minimal (I2 = 26.9%). After adjusting for the protective effects of antisecretory drugs, the odds ratios increased to 1.94 (95%CI 1.54–2.46).

Conclusion

This analysis suggests that H. pylori increases the risk of LDA ulcers by almost 70% in a population where some were taking proton pump inhibitors and/or other acid suppressants. Without antisecretory drugs, the risk almost doubles. Clinically, these findings may support the use of a test‐and‐treat approach to H. pylori in LDA users, particularly those already at higher risk of developing peptic ulcers.
Clinical, Sonographic, and Electrophysiologic Longitudinal Features of Chronic Inflammatory Demyelinating Polyneuropathy
Authors: Fisse Anna Lena , Pitarokoili Kalliopi , Trampe Nadine , Motte Jeremias , Kerasnoudis Antonios , Gold Ralf , Yoon Min‐Suk
Published: November 2018

BACKGROUND AND PURPOSE

Several studies have aimed to find potential biomarkers to simplify the diagnosis of chronic inflammatory demyelinating polyneuropathy (CIDP) and to monitor and predict the disease course. However, reliable markers are still lacking. We aimed to investigate whether high‐resolution nerve ultrasound (HRUS) is suitable for monitoring the long‐term clinical course of CIDP.

METHODS

Twenty patients fulfilling the definite diagnostic criteria of CIDP received clinical examination, evaluation of the INCAT (inflammatory neuropathy cause and treatment) overall disability sum score (ODSS) as well as nerve conduction studies, and HRUS every 6 months over a median follow‐up time of 34 months. Patients were divided into clinically stable/regressive disease course or progressive disease course according to the development of the ODSS.

RESULTS

The intranerve cross‐sectional‐area (CSA) variability of the nerves of the lower extremity increased with disease progression, whereas it remained unchanged in patients with a stable or remitting disease course.

CONCLUSION

Nerve ultrasound can be used as a method to objectify the long‐term disease course in CIDP patients. The intranerve CSA variability is suitable for monitoring the clinical course of patients with CIDP.
Paediatric new‐onset seizure clinic in Australia: Experience and lessons learnt
Authors: Shah Snehal , Nagarajan Lakshmi , Palumbo Linda , Walsh Peter , Silberstein Jonathan , Cannell Patricia , Ghosh Soumya
Published: November 2018

Aim

A new‐onset seizure clinic (NOSC) was established at our hospital in 2011, with the aim to provide accurate diagnosis and appropriate management to children with new‐onset seizures or seizure mimics.

Methods

We report on the data analysis of the first 200 children seen in NOSC. A paediatric neurologist or paediatric/neurology trainee under supervision of a neurologist reviewed all the children. A detailed history and clinical examination were undertaken. Electroencephalogram (EEGs) were undertaken prior to clinic review in most emergency departments. Children were classified as ‘epilepsy positive’ (EP+) or ‘epilepsy negative’ (EP−) after the first consultation.

Results

Of 200 patients, 109 were classified as EP+: generalised epilepsy in 57 of 109, focal in 36, childhood seizure susceptibility syndrome in 26 and epileptic encephalopathy in 5. EEG was available in 192: in 117, it was abnormal – 23 with background abnormalities and 109 with epileptiform activity. Of the 109 patients, 80 were commenced on anti‐epileptic drugs (AEDs): 12 were able to come off medication after seizure‐free period, 61 were controlled on AEDs and 7 were refractory. Children were followed up for 12–48 months. None of the children had diagnosis revised on follow‐up.

Conclusions

This is the first Australian study to report on a large cohort of children from a NOSC. An EEG and a paediatric neurologist assessment is a good combination to enable diagnostic accuracy: In the first 200 patients seen, there were no revisions of the initial diagnosis on follow‐up.
Knowledge Construction in Public Administration: A Discourse Analysis of Public Value
Authors: Wallmeier Franziska , Helmig Bernd , Feeney Mary K.
Published: November 2018

Public administration is a relatively young field with a growing academic community. Against the background of enduring discussions about theory and increasing research output and diversification within the field, the authors apply the sociology of knowledge approach to discourse that combines discourse theories and a social constructionist tradition to the exemplary case of “public value” research. The authors scrutinize 50 articles from 12 journals over 18 years to trace the development of public value as a concept in public administration research. Drawing from this exemplary case, they develop propositions and propose a framework for knowledge construction that is uniquely characterized as public administration. From the anchor points of manageability, economization, and democratic accountability, the authors develop a framework for analyzing and investigating knowledge development in other concepts such as network governance, representative bureaucracy, and coproduction.
Rethinking Social Amplification of Risk: Social Media and Zika in Three Languages
Authors: Wirz Christopher D. , Xenos Michael A. , Brossard Dominique , Scheufele Dietram , Chung Jennifer H. , Massarani Luisa
Published: November 2018

Using the Zika outbreak as a context of inquiry, this study examines how assigning blame on social media relates to the social amplification of risk framework (SARF). Past research has discussed the relationship between the SARF and traditional mass media, but the role of social media platforms in amplification or attenuation of risk perceptions remains understudied. Moreover, the communication and perceptions of Zika‐related risk are not limited to discussions in English. To capture conversations in languages spoken by affected countries, this study combines data in English, Spanish, and Portuguese. To better understand the assignment of blame and perceptions of risk in new media environments, we looked at three different facets of conversations surrounding Zika on Facebook and Twitter: the prominence of blame in each language, how specific groups were discussed throughout the Zika outbreak, and the sentiment expressed about genetically engineered (GE) mosquitoes. We combined machine learning with human coding to analyze public discourse in all three languages. We found differences between languages and platforms in the amount of blame assigned to different groups. We also found more negative sentiments expressed about GE mosquitoes on Facebook than on Twitter. These meaningful differences only emerge from analyses across the three different languages and platforms, pointing to the importance of multilingual approaches for risk communication research. Specific recommendations for outbreak and risk communication practitioners are also discussed.
The Partisan Composition of Cantonal Governments in Switzerland, 1848‐2017. A New Data Set
Authors: Walter André , Emmenegger Patrick
Published: November 2018

Scholars increasingly use Swiss cantons to examine the effect of democratic processes and institutions on political, economic and social outcomes. However, the availability of political indicators at the cantonal level is limited, in particular for longer periods of time. We introduce a novel data set on the ideological and partisan composition of cantonal governments, covering the period 1848‐2017 for most cantons. In this research note, we describe our data collection efforts and present some descriptives on the political development of cantonal governments in order to illustrate the data's potential. In particular, we look at the political strength of different parties and factions, the number of parties in government, government volatility and the nationalization of the party system. Our data thus provide new opportunities to examine political, economic and social outcomes as well as the formation of party systems in the Swiss cantons.
Gender and the Politics of Marijuana
Authors: Elder Laurel , Greene Steven
Published: November 2018

Objectives

The objectives of this study were to understand why, even though women are more liberal than men on a broad range of issues, when it comes to the increasingly prominent issue of marijuana legalization, the direction of the gender gap is reversed, with women more conservative than men.

Methods

Relying on a 2013 Pew survey—unique for the extensiveness of its marijuana questions, including marijuana usage—we explore and attempt to explain the nature of this unusual gender gap. We test several hypotheses rooted in the different life experiences of women and men.

Results

We find that women's role as mothers cannot explain this gap, and that mothers are in fact no different from those without children in terms of their support for marijuana policy, as well as their reported use of marijuana. The greater religiosity of women does play a prominent role in the gender gap on marijuana policy, but does not account for the full difference of opinion between women and men. Our findings suggest that men's greater propensity relative to women to use marijuana is a major driver behind the gender gap.

Conclusions

Not only are attitudes on marijuana legalization likely to continue to liberalize, but as marijuana legalization and marijuana use become normalized, rather than viewed as immoral and dangerous behavior, the existing gender gap should shrink.
Donor incentives improve cardiovascular disease risk profile and donation rates
Authors: Goel Ruchika , Kessler Debra , Nandi Vijay , Ortiz Caroline , Hillyer Christopher D. , Shaz Beth H.
Published: November 2018

BACKGROUND

Blood centers may offer point‐based reward systems or cardiovascular disease (CVD) screening to incentivize donors. However, combining these incentives to improve CVD risk and blood donation rates has not been studied.

STUDY DESIGN AND METHODS

Study was a three‐arm prospective controlled trial: Group 1, control (routine points, no CVD screening); Group 2, CVD screening with routine points; and Group 3, CVD screening plus incentive double points. The primary objective was to determine if double versus routine incentive points led to improvement or maintenance of CVD risk profile assessed using self‐reported changes in 1) reading food labels for calorie and fat content, 2) exercising daily, 3) reduced fat intake, and 4) increase in eating fruits and vegetables. Outcomes were compared at first and final (2‐year) follow‐up visits. As secondary outcome, median blood donation rates before enrollment and during study were compared.

RESULTS

A total of 570 donors (290 in Group 1, 134 in Group 2, 146 Group 3) were selected. At first follow‐up visit, 71.4% in Group 3 versus 62.0% in Group 2 subjects reported at least one of four positive behavioral changes (p < 0.001). Increase in reading food labels for calorie and fat content was the most common change and higher in Group 3 (Group 3 from 60.9% to 79.1%; Group 2 from 67.6% to 77.5%; p < 0.001). Final evaluation showed significant increase in self‐reported exercise in Group 3 only (from baseline 52.9% to 68.3%; p < 0.05). Group 3 reported higher increase in median number of donations/year during study enrollment (6.8 [IQR, 4.3‐12] vs. baseline 4.6 [IQR, 3.2‐7.1] donations/year) than Group 2 (5.6 [IQR, 4.2‐10.5] vs. baseline 4.9 [IQR, 3.5‐10.2]) and Group 1 (4.4 [IQR, 2.7‐8.0] vs. baseline 4.4 [IQR, 2.5‐6.0] donations/year; p < 0.001).

CONCLUSION

Positive donor reinforcement (double vs. routine points) resulted in better self‐reported health maintenance behavior and increased donation rates.
THE EFFECT OF SIGNIFICATION, RESOURCE DOMINATION, AND LEGITIMACY AND INCLUSIVE EDUCATION LEGITIMACY ON INCLUSIVITY OF ELEMENTARY SCHOOL IN SURAKARTA CITY
Authors: Karsidi Ravik , Tri Kartono Drajat , Wulansari Anggoro
Published: November 2018

AbstractInclusive education is still new and faces many problems in education service in Indonesia. This research aimed to find out the effect of signification, resource domination, and legitimacy on inclusivity of education and to find out the forms of signification, resourcedomination, and legitimacy in inclusive education in fiteen Elementary Schools organizing inclusive education in Surakarta This research employed a combined quantitative and qualitative method with embedded concurrent strategy. Data collection was carried out using questionnaire, interview, and observation. The subject of research was teacher with confidence level of 95%, and quantitative sample consisted of 246 respondents. The informant for qualitative data consisted of 17 persons taken purposively, using maximum variation sampling technique. The analysis of data was conducted using simple and multiple linear regressions equipped with description of qualitative data using Anthony Giddens’ structuring theory.The result of research show that education inclusivity belonged to low category. The result of linear regression calculation showed that the relationship between signification and education inclusiveness was fairly strong and positive (59.2%). The relationship between resource domination and education inclusiveness was fairly strong and positive (77.3%). The relationship between legitimacy and education inclusiveness was fairly strong and positive (66.6%). The result of multiple regression showed that the relationship between signification, resource domination and legitimacy was simultaneously strong and positive (81%). The forms of signification, domination and legitimacy of incusive education were includeimmaterials, such as work culture and religious belief values affecting the diversity of education inclusivity.Considering the analysis conducted show that the implementation of inclusive education is still far from its ideal indicators. Many requirements should be met to organize the inclusive education to make this city fasible to be called inclusice city.
RELIGIOUS EDUCATION AND CONTAINMENT OF RADICAL ELEMENTS: THE CASE OF PONDOK SCHOOLS IN MALAYSIA
Authors: Fathil Fauziah , Oktasari Wiwin
Published: November 2018

Islam and militant activities are indeed two ill-assorted and incompatible elements. While the former enjoins harmony and peace, the latter is essentially destructive in nature with no regard for either lives or properties The occurrence of many events which involved radical or militant elements today caused a growing concern that education too, might have been used by some irresponsible groups to spread their radical ideas in order to recruit followers or supporters where young minds are taught to hate people of other beliefs or ideologies and to commit destructive acts. In Malaysia, while phenomenon involving radical ideas is generally under control, still there have been some allegations that a certain style of education particularly of pondok system, being involved in militant-related activities. Based on qualitative approach or content-analysis, this paper attempts to seek out reasons for such allegations, highlighting certain issues and prior events that happened in the country which might have contributed to these contentions. The paper also provides possible means and ways, in view of the existing scenario in Malaysia, in making sure that religious education in the country remains free from the unwanted radical elements or ideas.
ISLAMIC RELIGIOUS VALUE IN TRADITIONAL CEREMONY OF BEGALAN BANYUMASAN AS EDUCATIONAL CHARACTER FOR STUDENT AT SENIOR HIGH SCHOOLS IN CENTRAL JAVA
Authors: Saddhono Kundharu , Kurniawan Alva
Published: November 2018

The purpose of this paper is to describe: (1) the form of Begalan traditional ceremony, (2) the meaning contained in brenang kepang, (3) the religious values of Islam in a Begalan traditional ceremony. This research is descriptive qualitative. The data collection techniques in this study are observation, interview, and reviewing documents and archives. The object of this study is a religious value in a traditional ceremony of Begalan Banyumasan. The data analysis technique in this research is qualitative descriptive analysis and interactive. Begalan Banyumasan traditional ceremony is a form of ritual to get rid of negative things. From the order of performance time, speech, and tools brought in Begalan have meaning and religious value. Therefore, the traditional ceremony of Begalan Banyumas is very suitable as a source of educational character in schools.
CHALLENGES AND EVOLUTION OF HIGHER EDUCATION IN MALAYSIA
Authors: Mohd Zain Norliza , Aspah Velantina , Abdullah Normazni , Ebrahimi Mansoureh
Published: November 2018

Education is a process that develops human abilities and attitudes. Higher education began expanding its reach after WWII due to the growing political awareness of its importance for a nation’s future prospects. This study focuses on how higher education impacted Malaysian graduates by reviewing the system’s development from 1957 to present day and even beyond to 2025. A qualitative approach is used, based mostly on books, journals and qualified papers. We identify how Malaysia’s system of higher education system ensured the future employment of its graduates. In addition, we provide the set of governmental guidelines that help maintain and enhance the system’s production of marketable graduates; thus, ensuring their employability in the global job market.
SYMBOLISM IN SHALAT (PRAYER): A CONCEPTUAL STUDY ON SHALAT AS THE METHOD OF ISLAMIC EDUCATION
Authors: Sholeh Muhammad Muhtar Arifin
Published: November 2018

There is no doubt about the importance of shalat (prayer). As mentioned in the verses of al-Quran and some ahaadiits (prophet traditions), there are some importance of prayer, i.e. as the pillar of ad-diinul-Islam, the character of Muttaqiin (pious people), the direct order from Allah, the first-accounted ‘amal (action) in the hereafter, the standard of goodness, the guard from badness, the prove of gratitude, the border between believer and unbeliever, etc-etc. In addition, shalat has many important symbolic meanings which should be implemented in the real life in this world. Symbol can be defined as, by Victor Turner, "a thing regarded by general consent as naturally typifying or representing or recalling something by possession of analogous qualities or by association in fact or thought“ (Turner, 1967:19). Shalat is the symbol of life; Shalat has many values which could be implemented in the life. Symbols in shalat can be traced in its requirements, its movements, its recitations, and symbol of congregation (jama’ah). Symbol can be functioned by understanding and implementing it. Furthermore, shalat has four functions, i.e. communicative, educative, integrative, and safety function. In educative function, shalat can be used as a method of Islamic education. The function of shalat can be played by understanding shalat and implementing it. The main purpose of the paper is to explore symbolic meanings of shalat, in order that Muslims can understand and implement those meanings in the real life. In other words, Muslims are hopefully able not only “to do shalat (prayer)” but also “to establish it”. Both “ritual prayer” and “actual prayer” have to be implemented in the life. Allah Ta’alaa said, in the translation from al-Quran, “And keep up prayer (establish prayer) and pay the poor-rate and bow down with those who bow down (QS al-Baqarah 2:43). In the context of this ayat, “ritual prayer” is to establish prayer, and “actual prayer” is to pay the poor-rate.
THE EXPERIENCES AND PERSONAL RELIGIOUS BELIEFS (PRB) OF UIN WALISONGO SCIENCE TEACHERS AS A FRAMEWORK FOR UNDERSTANDING THE RESHAPING OF THEIR BELIEFS AND IMPLEMENTATION IN BASIC BIOLOGY LEARNING
Authors: Nur Khasanah Nur Khasanah , Sajidan Sajidan , Baskoro Baskoro , Sarwanto Sarwanto
Published: November 2018

This research investigates the role of experience in relation to personal religion beliefs teachers and implementation in basic biology learning. The study adopted a social-cultural constructivist perspective using an interpretive approach. The research was guided by teachers’ interpretations of their experiences related to basic biology learning. These interpretations are re-interpreted to find meaningful conceptual categories (grounded in the data) from which to build a model to understand the influence of experiences within socio-Islamic culture on teachers’ beliefs and implementation in basic biology learning. Data was collected from five teachers using interviews and observations. The findings of this study suggest that it was mainly teachers’ personal religious beliefs and experiences that shaped their beliefs and implementation in basic biology learning. The research also led to a model, constructed on the basis of the data analysis, which suggests an explanation of how teachers’ personal religious beliefs and experiences influence their beliefs and implementation in basic biology learning.
PROBLEMS AND PROSPECT OF ISLAMIC DA’WAH IN NASSARAWA EGGON LOCAL GOVERNMENT AREA, NASARAWA STATE, NIGERIA
Authors: Maga Mohammed Sule
Published: November 2018

AbstractDa’wah is a duty for all Muslims. The Glorious Qur’an as the Muslim’s most authentic Book (Kitab) provides the basic principles of Da’wah methodologies to be applied by the Muslims Da’i (preacher) in the Da’wah field. This paper, therefore, attempts to provide the much-lacking information on the problems and prospect of Da’wah in Nassarawa Eggon. It looks into the challenges and problems faced by the Da’wah movement and also examines the reasons for the slow progress of Islamic Da’wah in the area. This is crucial because necessary actions could then be taken or solution is sought to ensure the smooth progress of Da’wah activities in Nassarawa Eggon. It examines the prospect of Islamic Da’wah and the efforts of the Muslim community towards the future and progress of Islamic Da’wah in Nassarawa Eggon in years to come.
ANJAKAN PARADIGMA WAQAF BERASASKAN PRINSIP MASLAHAH AL-MURSALAH (PARADIGM SHIFT IN WAQF BASED ON THE PRINCIPLES OF MASLAHAH AL-MURSALAH)
Authors: Husain Mohd Huefiros Efizi , Abd Majid Mohd Nasir , Abdul Rab Muneer Ali
Published: November 2018

Relationship among Muslims since the time of Adam a.s., there is contained all the admirable values that can be applied today. Disclosure of such values includes properties helping to ease the burden of the Muslim’s region. Not only energy aid or grant of land, even from a financial point of also highly expected. Waqf is a way to break the impasse in the considerable challenge to the demands and needs of the various categories of property surplus sharing mechanism with the purpose of the public good. The distribution is given to strengthen the Muslim’s relationship and the smooth running of daily life. Therefore, this study will describe the practice of waqf in line with technology and the development of the country in nurturing tolerance community. The objective of this study dismantling the waqf practices based on transformation of Maslahah al-Mursalah. Next explained Maslahah al-Mursalah establishment and implementation of the subject matter. The methodology of study used qualitative methods to achieve the objectives of the study involving literature methods. The results showed clearly Maslahah al-Mursalah applied in practice transformation endowment contract as today.
PERANAN ZAKAT DALAM MERAWAT JIWA (ZAKAH AS A SOUL TREATMENT)
Authors: Masroom Mohd Nasir , Muhamad Siti Norlina , Panatik Siti Aisyah
Published: November 2018

Worship in Islam is a form of obedience and manifestation of a Muslim's bondage to Allah SWT. However, worship also has certain advantages or benefits to the soul. This article aims to explain how zakat be able to improve the soul well-being. The method used by analyzing the views of Islamic scholars on the advantages of zakat practice. In addition, the Qur'anic verses and Hadiths are used to reinforce the argument. This article found that sincerity and understanding of the purpose of zakat are two significant elements in order to improve the soul. As such, zakat cultivated positive attitudes, such as sincerity, compassion and gratitude. On the contrary, zakat can avoid negative attitudes, such as greedy, arrogant and selfish. Therefore, sincerely and understanding the purpose of zakat can be used as one form of treatment for non-psychotic mental patients. This article is intended to provide guidance and enlightment to psychologists, counselors and counselors to treat patients in the Muslim community.
KECEKAPAN PENGURUSAN KEWANGAN DAN PENGURUSAN AGIHAN ZAKAT: KAJIAN TERHADAP MAJLIS AGAMA ISLAM JOHOR (EFFICIENCY OF FINANCIAL AND ZAKAT DISTRIBUTION MANAGEMENT: A STUDY AT JOHOR ISLAMIC RELIGIOUS COUNCIL)
Authors: Aminuddin Ahmad Fathi , Wahid Hairunnizam , Mohd Nor Mohd Ali
Published: November 2018

The current situation shows that there is still a negative perception among Muslim societies towards zakah institutions in Malaysia. Several previous studies have shown that the negative perception still exists due to the lack of confidence among the societies against the zakah institutions in term of the efficiency of financial management as well as zakah distribution management to asnaf. The response is likely to exist due to some of the negative issues that still occur, such as the efficiency of zakat distribution by the State Islamic Council (MAIN) including the issue of excess amount zakah that are not distributed annually and the distribution of zakat to eight groups of asnaf including the issue of asnaf priority that should be paid attention by zakat institutions. Thus, a study was conducted to measure the efficiency of financial management and the zakah distribution management by Majlis Agama Islam Negeri Johor (MAINJ), using cash flow ratio as a proxy for financial performance and categorizing the performance efficiency of the zakat distribution into two; namely financial efficiency (excess of zakat annually) and non-finance (asnaf priority). A simple regression model is also used to view MAINJ's zakat distribution pattern every year. This study uses the annual financial statement and the data of zakat collection and distribution by MAINJ for the year 2000 to 2013. The findings show that the performance of zakat distribution in financial aspect has increased from year to year indicating improvement of MAINJ's financial performance. While from the non-financial distribution aspect, the average score of zakat distribution was at the best value indicating the amount of zakat allocated following the priority of the asnaf as suggested by Imam As-Syafie. The results of the study can be used as a benchmark of performance efficiency of financial management and efficiency of the zakat distribution management for zakat institutions, especially MAINJ in order to improve the performance of zakat distribution in Johor and Malaysia in general.
PENGURUSAN KECAIRAN INSTITUSI KEWANGAN ISLAM (IKI) DI MALAYSIA: ANALISIS PERBANDINGAN ANTARA KEPERLUAN INTERNATIONAL ISLAMIC LIQUIDITY MANAGEMENT (IILM) BERBANDING PASARAN WANG ANTARA BANK SECARA ISLAM (IIMM) (LIQUIDITY MANAGEMENT OF ISLAMIC FINANCE MANAGEMENT IN MALAYSIA: COMPARATIVE ANALYSIS BETWEEN INTERNATIONAL ISLAMIC LIQUIDITY MANAGEMENT (IILM) AND ISLAMIC INTERBANK MONEY MARKET)
Authors: Shahabudin Najibah Khairiyah , Noordin Kamaruzaman
Published: November 2018

Malaysia is a country that leads in the Islamic Financial sector. In fact, Malaysia is the first country that has established Islamic Interbank Money Market (IIMM) while banks in other countries only provide high liquidity instruments without platform. However, in 2010, International Islamic Liquidity Management (IILM) has been established to manage the liquidity globally. IILM is led by Malaysia because of its authority in Islamic Finance. Since its establishment, IILM manages the global liquidity through short term wakalah sukuk only. Thus, why is IILM needed if it only issues one instrument? In comparison, IIMM have many high liquidity instruments to meet the needs of IFI in Malaysia. In fact, IIMM is a strong platform for managing liquidity in Malaysia. By using the interview and longitudinal method, the researchers found out that IILM does not threaten the preexisting IIMM in Malaysia because both IILM and IIMM have different missions and visions. Therefore, IIMM is needed in Malaysia. However, IILM is not only needed in Malaysia but also globally. The world acceptance on the IILM’s short-term instrument would help in solving the issues regarding the excess liquidity in IFI. However, IILM still have to make various improvements to achieve its own objectives.
HEALTHY LIFESTYLE EDUCATION FROM HALAL NUTRACEUTICAL CONCEPT
Authors: Mohamad Abdul Aziz , Baharuddin Ahmad Syukran , Ruskam Aminuddin
Published: November 2018

The world is witnessing a return to what is natural, both environmentally and back to fitrah, our innate nature. This does not apply to food, and cosmetic sector only, but also the health and nutraceutical sectors. One of the evidences is the fastest growing sectors in the global personal care market and nutraceutical market as dictated by consumer lifestyle and awareness. This article aims to explore on the healthy lifestyle education contained in nutraceutical concept based on Islamic perspectives. This study used document analysis on primary and secondary documents as methodological approach. This study found that Arab-Islamic medicine or Greco-Arab refers to medicine developed in the Golden Age of the Islamic Civilization. It is extended from Spain in the west to Central Asia and India in the East. ‘Prophetic Medicine’ although popular amongst the masses of Muslims because of its doctrinal and theological contents was considered by most Muslim historians and physicians as distinct from scientific and analytical Islamic Medicine. Medicine of the Prophet is a combination of religious and medical information, providing advice and guidance on the two aims of medicine. First the preservation of health and second the restoration of health based on the Qur’anic guidance and the Prophetic traditions.