bluuebunny/crossref_metadata_2025 huggingface dataset:
O gênero Olpidiopsis (Oomycota) no Nordeste do Brasil
Authors: Rocha José de Ribamar de Sousa , Machado Joseane Lustosa , Silva Janete Barros da , Trindade Júnior Osiel César da , Santos Leilane de Abreu , Rodrigues Edilson Páscoa , Cronemberger Áurea Aguiar
Published: December 2018

Resumo Estudos sobre a diversidade de oomicetos foram realizados de 1998 a 2016, na Bahia, Maranhão e Piauí, e parasitas biotróficos holocárpicos zoospóricos de quitrídias, glomeromicetos e oomicetos foram identificados como Olpidiopsis achlyae, O. aphanomycis, O. fusiformis, O. karlingae, Olpidiopsis sp1 e Olpidiopsis sp2. A ocorrência de O. karlingae é novo relato para a América do Sul e de O. aphanomycis, para o Brasil. Os táxons encontrados foram descritos, ilustrados e comentados. A diversidade de termos da literatura especializada para identificação das estruturas morfológicas de Olpidiopsis foi padronizada. São propostas as sinonímias de O. braziliensis (= Pseudolpidium achlyae) com O. fusiformis e de Cornumyces karlingae com O. karlingae.
Multi-walled carbon nanotube reinforced polymer as a bonded repair for Al 2024-T3 fatigue crack growth
Authors: Monsalve Alberto , Solís Roberto , Díaz Mauricio , Carrasco Sebastián , Artigas Alfredo
Published: December 2018

ABSTRACT The influence on multi walled carbon nanotubes (MWCNT, or simply CNT) as a reinforcement material in an epoxy resin in order to decrease the fatigue crack propagation rate in the 2024 T3 aeronautical Al alloy was studied. CT samples were pre-cracked in a resonant fatigue machine until a 4 mm pre-crack length. Four groups of samples were considered: a non-repaired reference group, two groups repaired with epoxy resin reinforced with two CNT proportions (0.5 and 1 vol %) and a group repaired by the conventional “stop drill” technique. The crack was propagated until a length of 16 mm, measuring the number of cycles to this crack propagation. Resin Hysol EA9320 NA was used, mixing it with the CNT and the hardener, by ultrasonic stirring. S-N curves (stress vs number of cycles) were plotted obtaining an increment of 104% for a 0.5 vol% of CNT, 128% for 1 vol% of CNT and 400% for “stop drill” repairing. These results were referred to the non-repaired samples at the lower load level. These results showed that in repaired samples with CNT reinforced resin, the initiation and propagation of cracks would be delayed, constituting this method a reasonable and convenient repairing procedure useful for aeronautical cracked structures.
Platelet yield and recovery following the PRGF-U1 protocol in a Peruvian population.
Authors:   School of Stomatology, Univer-sidad Nacional de Trujillo. Trujillo, Peru. Dental Health Center San Mateo. Trujillo, Peru., Aguirre-Aguilar Augusto , Arbildo-Vega Heber ,   School of Stomatology, Univer-sidad Nacional de Trujillo. Trujillo, Peru. Dental Health Center San Mateo. Trujillo, Peru., Aguirre-Aguilar Antonio ,   School of Stomatology, Univer-sidad Nacional de Trujillo. Trujillo, Peru. Dental Health Center San Mateo. Trujillo, Peru.
Published: December 2018

Objective: To determine the platelet recovery and yield of the PRGF-U1 protocol in a Peruvian population. Methods: An observational, descriptive and cross-sectional study was conducted with a simple random probability sample of 32 patients who attended the Laboratorio Scalab in Trujillo, Peru. A blood sample was taken from each patient in order to obtain the concentration of platelets and before and after the PRGF-U1 protocol, in order to determine platelet recovery and yield. To compare basal platelet concentrations and platelet recovery and yield with gender and age, the chi-square test, Student's t-distribution and Pearson's correlation coefficient were used considering a significance level of p<0.05. Results: Platelet yield was less than 2.2 in two patients and greater than or equal to 2.2 in 30 patients; platelet recovery was equal to 0.4 in 30 patients and greater than 0.4 in two patients. A statistically significant relationship (p<0.05) between basal platelet count and age was found when comparing basal platelet count, platelet recovery and platelet yield according to gender and age, but no significant relationship between the other variables (p>0.05). Conclusion: The PRGF-U1 protocol presents optimal platelet yield and minimal expected platelet recovery.
A comparative study of digital lateral radiography and virtual cone-beam computed assisted cephalogram in cephalometric measurements
Authors:   Radiología Bucal y Maxilofacial, Universidad de San Martín de Porres, Lima, Perú., Calle-Morocho Jesica , Morales-Vadillo Rafael ,   Radiología Bucal y Maxilofacial, Universidad de San Martín de Porres, Lima, Perú, Guevara-Canale Janet ,   Patología y Medicina Oral y Maxilofacial, Universidad de San Martín de Porres, Lima, Perú., Alva-Cuneo Carlos ,   Radiología Bucal y Maxilofacial, Universidad de San Martín de Porres, Lima, Perú.
Published: December 2018

Objectives: To assess discrepancies in cephalometric measurements from digital lateral radiography and virtual cone-beam computed assisted tomography cephalogram. Materials and methods: Forty digital lateral radiographs and forty virtual cephalograms obtained by cone-beam computed assisted tomography were analyzed, corresponding to forty patients from the nstituto de Diagnóstico Maxilofacial in Lima, Peru. The principal investigator, who had been previously calibrated, made two measurements within a timespan of fifteen days using the analysis of Steiner and the NemoCeph software, and the difference between the obtained measurements was evaluated to determine if it was significant. Results: For digital lateral radiographs the difference varied between 0.00º - 0.45º and 0.01mm - 0.16mm, with statistical significance for distance between Pg and NB for lateral virtual cephalograms between 0.03º - 0.73º and 0.01mm - 0.43mm, with statistical significance for SE distance. The comparison between the two types of image in the first measurement showed a difference of 0.08º - 1.15º and 0.00mm - 1.43mm with statistical significance for four angular measurements and one linear. The comparison between the two types of image in the second measurement showed a difference of 0.13º - 1º and 0.02mm - 1.32mm with a statistically significant difference for three angular and two linear measurements. Conclusions: The difference between the two types of image is minimal; Both evaluated methods can be used effectively.
Pseudomembranous candidiasis by Candida tropicalis in an immunocompromised patient: Case Report.
Authors:   Facultad de Odontología de la Universidad Católica de Santa María, Arequipa, Perú., Obando-Pereda Gustavo
Published: December 2018

Pseudomembranous candidiasis is the most frequent type of infection by Candida spp., and Candida albicans is the most common species to cause it. Candidiasis can be due to other Candida species less frequently, as is the case of Candida tropicalis a pathogenic species that can cause infection in immunocompromised patients. The aim of this case report is to describe a pathological condition produce by Candida tropicalis.
Prosthetically adverse implant position: an aesthetic surgical-prosthetic solution. Case report
Authors:   Universidad Nacional Mayor de San Marcos. Lima. Perú., Chale-Yaringaño Andrés , Castro-Rodríguez Yuri ,   Universidad Nacional Mayor de San Marcos. Lima. Perú., Grados-Pomarino Sixto ,   Universidad Nacional Mayor de San Marcos. Lima. Perú.
Published: December 2018

Clinical case of a 43-year-old female patient treated at the clinic of Universidad Nacional Mayor de San Marcos, Peru, in 2015 for aesthetic problems in the activation of a unitary implant placed at a distal and vestibular direction from the ideal position. The clinical examination revealed the vestibularization of the implant at the level of the upper right central incisor with the healing abutment visible above the gingival line and high gingival smile. Connective tissue grafts and ovoid pontics were carried out in order to improve the characteristics of the peri-implant tissue. This clinical case evidenced an improvement of the soft tissue profile and patient satisfaction regarding her smile. The management of a vestibularized implant may be solved through the management of ovoid pontics and connective tissue grafts.
Сross-sectional anatomic study of direct positional relationships between mandibular canal and roots of posterior teeth using cone beam computed tomography
Authors:   Human Morphology Department, Belarusian State Medical University, Minsk, Belarus., Kabak Sergey Lvovich , Zhuravleva Natallia Victorovna ,   Human Morphology Department, Belarusian State Medical University, Minsk, Belarus., Melnichenko Yuliya Michailovna ,   Human Morphology Department, Belarusian State Medical University, Minsk, Belarus., Savrasova Nina Alexandrovna ,   Radiation Diagnosis and Radiation Therapy Department, Belarusian State Medical University, Minsk, Belarus.
Published: December 2018

Objectives: To establish the frequency of the various types of direct contacts of the root apices with the wall of the mandibular canal and to determine gender differences in number of such contacts in a selected Belarusian population using cone beam computed tomography. Methodology: One hundred and two cone beam computed tomography scans were analyzed to classify the types of contact and three-dimensional relationship between the mandibular teeth and the mandibular canal. Results: The direct contact between the teeth and the mandibular canal was observed in 63.7% of patients. Overall 300 roots of 189 teeth were in direct contact with the mandibular canal: 9.3% were second premolars, 14.7% were first molars, 33.8% were second molars and 50.0% were third molars. There were no statistically significant differences in the number of teeth with direct contact with the mandibular canal between males and females. Conclusion: The direct contact of the root apices with the mandibular canal was most often found in the second and third molars. The root apices of the third molars had the greatest variability of location relatively to the mandibular canal.
Management of merged external/internal root resorption using CEM cement: a case report.
Authors:   Department of Cariology Endodontology Pedodontology, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Netherlands. Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mirmohammadi Hesam , Asgary Saeed ,   Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Published: December 2018

Chronic pulpal inflammation and infection are the main predisposing factors for internal and external root resorption (IRR & ERR); however, merging of IRR and ERR is a rare lesion which rigorously alters the anatomy of root canals. This study reports a case of merged IRR and ERR in an asymptomatic maxillary left central incisor in a 33-year old Caucasian woman that was managed by one-visit root canal therapy (RCT) using calcium-enriched mixture (CEM) cement. Radiographic examination showed a short root with under-filled root canal obturation associated with ERR/IRR and an apical lesion. After thorough chemo-mechanical preparation, the root canal was obturated with CEM cement; one week later, the access cavity was permanently restored. Clinical/radiographic examinations at 1-year follow-up revealed uneventful healing, reestablishment of lamina dura and stabilization of the resorptive defects. The treatment outcome demonstrates that one-visit RCT using CEM cement may be a viable treatment option in cases with merged external/internal root resorption. Further clinical trials with a larger number of cases are suggested to document a higher level of evidence.
CUT&RUN with Drosophila tissues v1
Authors: Ahmad Kami
Published: December 2018

We have modified the Cleavage Under Targets and Release Using Nuclease (CUT&RUN) method for epigenomic profiling of histone modifications and chromatin proteins to use dissected Drosophila tissues. In CUT&RUN, cells or tissues are permeabilized and incubated under conditions where a factor-specific antibody can bind at sites of a chromatin protein. This antibody is then used to tether a protein A-micrococcal nuclease fusion protein, which upon activation releases specific protein-DNA complexes into the supernatant for paired-end DNA sequencing, and leaving the vast majority of DNA behind in the cellular pellet. CUT&RUN outperforms the most widely used Chromatin Immunoprecipitation (ChIP) protocols in resolution, signal-to-noise, and depth of sequencing required. Previous versions of CUT&RUN have used isolated nuclei, mammalian cultured cells, or yeast spheroplasts. Here we have modified the CUT&RUN protocol to manipulate imaginal discs and tissues dissected from larvae with magnetic beads without isolation of cells or nuclei. About 10 imaginal discs provides high-quality data for a histone modification or for a chromatin factor. A simple spike-in strategy is used for accurate quantitation of experiment yields and library preparation. From larvae to purified DNA, CUT&RUN requires 1-2 days with minimal handling after dissection.
Drug distribution imaging of rabbit whole-eye section by MALDI mass spectrometry v1
Authors: Mori Naoto , Mochizuki Takaharu , Yamazaki Fumiyoshi , Takei Shiro , Mano Hidetoshi , Matsugi Takeshi , Setou Mitsutoshi
Published: December 2018

Matrix-assisted laser desorption/ionization–imaging mass spectrometry (MALDI-IMS) evaluates drug distribution in biological samples. However, there have been few investigations of drug distribution in ocular tissues, including whole-eye segments. In the present study, we explored the spatial distribution of atropine in a whole-eye segment using MALDI-IMS. Atropine is a reversible muscarinic receptor used to treat various diseases. However, its distribution in ocular tissues remains unknown. A 1% atropine solution was administered to a rabbit and after 30 min, its eye was enucleated, sectioned, and analyzed by MALDI-IMS. Atropine accumulated primarily in the tear menisci but was found at substantially lower concentrations in the tissue surrounding the conjunctival sacs. Relative differences in atropine levels between the anterior and posterior regions provided insights into the post-instillation behavior of atropine. Atropine signal intensities differed among corneal layers and between the superior and inferior eyeball regions. Differences in signal intensity among tissues indicated that the drug migrated to the posterior regions via a periocular scleral route. This information is useful for atropine delivery and indicates that MALDI-IMS is effective for revealing drug distribution in whole-eye sections.
Learning Experiences of Students Who Are Hard of Hearing in Higher Education: Case Study of a South African University
Authors: Bell Diane , Swart Estelle
Published: December 2018

Students who are hard of hearing (HOH) are being granted access to university increasingly, yet they remain significantly under-represented and under-supported, often resulting in poor academic outcomes with elevated levels of attrition. This situation places a growing obligation on universities to improve the support provided to these students in order to have a positive influence on their overall academic experience and eventual economic independence. This trend is relevant to South Africa, where Higher Education Institutions (HEIs) are accepting and registering students with a hearing loss but are not providing adequate academic support and inclusive curricula. Furthermore, in South Africa, almost no research has been conducted concerning students who are HOH in higher education regarding their teaching and learning needs or the coping strategies which they use to survive academically. However, what is known is that, of those HOH students who do enter higher education, many do not graduate successfully (up to 75%) and, of those that do graduate, many continue to be excluded from professions. The aims of this article were to report on the teaching and learning experiences of students who are HOH at a South African university, who prefer to make use of spoken language, to share the daily barriers with which they are faced, and to provide recommendations for teaching and learning, as well as curricula transformation. This study adds to the existing body of knowledge on this topic in South Africa and could be relevant in similar contexts.
Tú y Usted en la ciudad de México. ¿Qué tanto y cómo influyen el sexo, la edad y el nivel educativo?
Authors: Cepeda Ruiz Cristal Yeseidy
Published: December 2018

In this study we focus on the second person singular pronouns tú and usted used in the Spanish of Mexico City, based on three social variables gender, age and educational level (of the speaker and the listener). Throughout the frequency and distribution of these pronominal forms, as well as according to the qualitative perception and the collaborators’ evaluation, we explore the current system of personal treatment and compare it with data obtained in previous studies. Our data indicates that the age, the educational level and the gender of the speakers are relevant in the choice of one or another pronominal form. The comparison with previous studies allows us to appreciate a slight increase of tú in front of usted as from the Seventies; it also allows us to show an age-graded pattern characterized by the use of tú when the speakers are young, and usted when they reach the adulthood. Quantitative and qualitative data come from 48 sociolinguistic questionnaires distributed among speakers from Mexico City as well as internal migrants residing in the Mexican capital, men and women of four generations and three different educational levels.
Sobre creo (que) subjetivo (e intensificador) en las sesiones de debate parlamentario
Authors: Soler Bonafont María Amparo
Published: December 2018

This paper presents a behavioral analysis of the doxastic form creo (que) as a subjectification modal verb, specifically in its manifestation as a pragmatic intensifier device in a Spanish parliamentary debate. Previous work on creo (que) has suggested that it is indeed an intensifier (Fuentes 2010, Brenes 2015, Cuenca 2015), although many pragmatic approaches to these doxastic verbal forms, not only in the context of Spanish (Hennemann 2012; Albelda, Briz, Cestero, Kotwica y Villalba 2014) but also from other languages (Lakoff 1972; Hooper 1975; Lysvag 1975; Fraser 1975, 1980; Holmes 1984; Caffi 1999, 2004), have classified creo (que) as a marker of attenuation. The goal of this investigation is to show a comprehensive description of the behavior of creo (que) in a Spanish parliamentary debate, especially focused on its development as a an intensifier. Using mixed qualitative and quantitative methods, the preselected doxastic form creo (que) is analyzed from a corpus of 351,888 words. Factors considered include formal features, meaning, aspects of face and other discourse features, with the purpose of providing a detailed explanation of the pragmatic procedure of creo (que).
Diccionario Geolectal de Cuba. Aspectos de la planta lexicográfica
Authors: Camacho Barreiro Aurora , García González Elisa , Hernández Valdés Lorena , Linares Terry Kelly , Triana Orozco Amalia
Published: December 2018

The Geolectal Dictionary of Cuba (DiGeCu) is an ongoing lexicographical project of the Institute of Literature and Linguistics of Cuba. It is proposed to order and lemmatize the geolectal information gathered by the linguistic Atlas of Cuba (ALCu) -principal result of the project “Elaboration of the Linguistic Atlas of Cuba (ALCu)” - published in five volumes. This article collects some aspects of the lexicographical plant (drafting plan) of the DiGeCu. This work is novel because it takes unprocessed geolectal information for lexicographic purposes and organizes, analyzes, processes and lemmatizes it. Its originality lies in its own source, the geolectal data itself and its methodological approaches, arising from Hispanic practices and the contribution of the team itself, composed of specialists in dialectology and lexicography. The Geolectal Dictionary and the academic works derived from it will undoubtedly be a fundamental source not only for other companies of this type, but also for studies on the Spanish of Cuba from different points of view; since there will be an inventory of Cuban atlas units processed with lexicographical rigor.
Episcleral venous pressure level in patients with thyroid associated orbitopathy
Authors: Potemkin Vitaly V. , Goltsman Elena V. , Kovaleva Maria S.
Published: December 2018

Thyroid associated orbitopathy (TAO) occurs in patients with various diseases of the thyroid gland. The levels of episcleral venous pressure (EVP), intraocular pressure and intraorbital pressure are inter- related. There are no precise data on the change of EVP in patients with TAO.

Purpose. To evaluate EVP in patients with compensated and sub-compensated TAO forms.

Methods. Data of 41 eyes of 22 patients were enrolled into the study. The main index to be evaluated was the EVP.

Results. EVP level was significantly higher in complete venous compression in the lower- temporal quadrant in patients with sub-compensated TAO stage (p = 0.013).

Conclusion. The degree of venous outflow obstruction and the EVP level of are interrelated. Thus, the level of EVP can be used as an additional factor in assessing the severity of the disease course and the treatment efficacy.
Risk prediction of posttraummatic enophthalmos development on the basis of orbital volume calculations using multislice computed tomography data
Authors: Davydov Dmitriy V. , Serova Natalya S. , Pavlova Ol'ga Yu.
Published: December 2018

Purpose. To elaborate a method of orbital volume measurement in patients with midface trauma at pre- and postoperative stages on the basis of multislice computed tomography (MSCT); to investigate the capabilities of orbital volume measurement to acquire additional diagnostic information and to estimate the risk of postoperative enophthalmos development.

Materials and methods. A total of 71 patients (100%) with midface trauma were examined at the Sechenov University clinic. At pre- and postoperative stages, all patients (n = 71, 100%) were examined using MSCT (Toshiba Aquilion One 640) with 0.5 mm slice thickness in bone and soft tissue regimen. To measure orbital volume, MSCT data were processed using Vitrea workstation: bone borders of the right and left orbit were marked before and after surgical treatment on every axial slice, and orbital volumes were presented in ml.

Results. Preoperative MSCT data management revealed increased orbital volume due to orbital trauma in 64 patients (90%), the difference between healthy and traumatized orbit was between 2 ml and 14 ml. In these patients, reconstructive surgical procedure was performed. In 7 patients (10%) with mild midface trauma, the difference between orbital volumes was less than 2 ml, this was considered as a positive prognostic factor, and these patients were not subjects to surgical treatment. After surgery, in 55 patients (77%) the orbital volume restored, the difference between orbital volumes was less than 2 ml. In 9 cases (13%), the difference in orbital volume was more than 2 ml, considered as adverse prognostic factor which means that there still was a risk of postoperative enophthalmos development. In this patient group, additional diagnostic examination was necessary, and patients required planning of residual enophthalmos surgical correction with MSCT control during the post-op period.

Conclusion. Postprocessing of the MSCT data gave the possibility to calculate pre-and postoperative orbital volume changes and present it in mathematical units (ml) in 3D mode. As the result the additional information can be acquired in order to identify the risk of postoperative enophthalmos.
Molecular genetic aspects of complicated myopia pathogenesis
Authors: Kulikov Alexey N. , Churashov Sergey V. , Reytuzov Vladimir A.
Published: December 2018

Complicated myopia (CM) is not only a refractive error but a complex, multifactorial disorder characterized by a mismatch between the optical power of the eye and the axial length that causes the image to be focused off the retina. Genetic factors in progressive myopia play a key role in determining the impact of ecologic factors on refraction development. The majority of genetic variants underlying CM are characterized by modest effect and/or low frequency, which makes them difficult to identify using classic genetic approaches. The genes identified to date account for less than 10% of all myopia cases, suggesting the existence of a large number of yet unidentified low-frequency and/or small-effect variants, which underlie the majority of myopia cases. Genome analysis revealed dozens of loci associated with non-syndromic myopia, and showed that refractive errors are associated with mutations in genes that are involved in the growth and development of the eye by regulating ion transport, neurotransmission, remodeling of extracellular matrix of the retina and other ocular structures. Genetic study of refractive error provides a unique opportunity to detect key molecules that may play important roles in the development of refractive error. Identifying the molecular basis of refractive error helps to understand mechanisms, and subsequently to design rational therapeutic intervention for this condition.
Upon possibilities of simultaneously “radical and sparing” endovitreal removal of choroidal melanoma
Authors: Yarovoy Andrey A. , Gorshkov Ilia M. , Korobov Egor N. , Yarovaya Vera A.
Published: December 2018

Relevance. The endoresection of the choroidal melanoma (CM) is carried out from its top to the base with the formation of surgical coloboma within the healthy choroid visible in the operating microscope, which does not guarantee the absence of residual tumor cells in it at the microscopic level. Excision of the choroid with a large amount of healthy tissues leads to a risk of unnecessary resection of functionally significant tissues with corresponding loss of vision, especially in juxtapapillary and paramacular localization of CM.

Purpose: to develop a method to increase the radicality of endovitreal removal of the choroidal melanoma while achieving the maximum functional result.

Material and methods. At the basis of the radical and sparing endovitreal removal of CM lays the principle of micrographic Mohs-surgery used in the treatment of skin cancer. When CM of paramacular localization is mushroom-shaped, the tumor peak often hangs over the macular zone and prevents its visualization and does not allow to determine true boundaries of the CM base in this area. In this situation, it is possible to carry out an endoresection of CM under video endoscopic control.

Results. According to the proposed method, 3 patients were operated: 2 men and 1 woman. All patients in the pre-operative period had exudative retinal detachment, in 1 of them it was vesicular. For the maximum period of observation, all 3 patients are alive, in none of them metastatic lesions and tumor recurrence were detected. All eyes have been preserved. The best corrected visual acuity was: in patient No 1 0.3; in patient No 2 0.4; in patient No 3 0.1.

Conclusion. The proposed treatment method makes possible to carry out the most radical endovitreal removal of CM, which at the same time is sparing for functionally significant healthy surrounding tissues with a decrease in intra- and postoperative complications.
Diagnosis and treatment of fungal keratitis. Part I
Authors: Skryabina Yelena V. , Astakhov Yuriy S. , Konenkova Yanina S. , Kasymov Farkhod O. , Zumbulidze Nataliya G. , Varganova Tatiana S. , Petukhov Vladimir P. , Pirgunova Alyona A. , Masian Janek , Klimko Nikolai N. , Bogomolova Tatyana S. , Desyatik Ekaterina A.
Published: December 2018

Fungal keratitis (FK) is a difficult diagnostic challenge for ophthalmologists.

The aim is to familiarize practicing physicians with the diagnostic algorithm worked out in the Ophthalmological Center of SPB City hospital No. 2 using modern research methods, and to assess the epidemiology of fungal keratitis in the North-West Region.

Materials and methods. Patients underwent laboratory diagnostics (fluorescence microscopy of corneal scrapings from the cornea, сulture on Sabouraud agar and broth), confocal in vivo microscopy, optical coherence tomography.

Results. During the period from 2007 to 2017, 41 cases of FK were identified in the City hospital No. 2, of which filamentous fungi were the causative agent in 32 cases (78%), yeast fungi in 9 cases (22%). Our analysis included patients with fungal keratitis over the past three years, all of them underwent a full diagnostic cycle. Filamentous fungi were found among 12 of them (63%), yeast in 7 (37%). Our data, considering the statistics of fungal keratitis in the North-West of Russia a region with a high level of urbanization and industrialization, and located in the temperate zone showed a predominance of filamentous fungi as pathogens (prevalence 1.3 times higher). Our scheme of keratitis diagnostics confocal in vivo microscopy, OCT, fungal culture is a reliable way to identify fungal pathogens in the cornea, and can be recommended for use in practical ophthalmology.
Pseudotumor or decompensated edematous proptosis?
Authors: Toropova Olga S.
Published: December 2018

The article presents the main differential diagnostic signs of pseudotumor orbit and decompensated edematous exophthalmos on the basis of its own clinical observation.
El Nuevo Tesoro Lexicográfico del Español (s. XIV-1726)
Authors: Nieto Jiménez Lidio , Alvar Ezquerra Manuel
Published: December 2018

En este trabajo se hace una rápida presentación del Nuevo Tesoro Lexicográfico del Español (s. xiv-1726), que es un diccionario de diccionarios. En primer lugar, se habla de los repertorios de léxico que se han tenido en cuenta para su elaboración, con una especial atención sobre Nebrija, por su importancia dentro de la lexicografía del español. Después, se presentan las decisiones más importantes adoptadas para la recogida de los materiales, así como algunos de los problemas surgidos para su lematización, y las soluciones adoptadas en la presentación de las informaciones.
Un vent nouveau pour les Éditions Robert. Dominique Le Fur Dir. (2007): Dictionnaire des combinaisons de mots: les synonymes en contexte, Paris, Le Robert, ‘Collection les usuels’, viii+1011 pages). Paul Bogaards, dir. (2007): Dictionnaire français-néerlandais; néerlandais-français, Paris-Utrech-Antwerpen, Le Robert-Van Dale
Authors: De Surmont Jean Nicolas
Published: December 2018

Reseña: Un vent nouveau pour les Éditions Robert. Dominique Le Fur Dir.(2007): Dictionnaire des combinaisons de mots: les synonymes en contexte, Paris, Le Robert, ‘Collection les usuels’, viii+1011 pages). Paul Bogaards, dir. (2007): Dictionnaire français-néerlandais; néerlandais-français, Paris-Utrech-Antwerpen, Le Robert-Van Dale.
Injurias, maldiciones y juramentos en la lengua española del siglo XVII
Authors: Tabernero Sala Cristina
Published: December 2018

En este artículo se analizan sociolingüísticamente las fórmulas blasfematorias, juramentos, palabras vedadas y maldiciones dispersas por más de seiscientas relaciones de causas inquisitoriales fechadas entre 1620 y 1655, como modo de acceso a la oralidad de aquellos años. Se atienden cuestiones de precisión terminológica relativas a la distinción entre blasfemia y juramento e insulto e injuria, que permiten el posterior estudio léxico-pragmático, lexicográfico y documental de los distintos términos y expresiones que les dan forma lingüística en la primera mitad del siglo XVII. Hábito lingüístico y desemantización, por un lado, y procesos de creación expresiva basados en el significado de las voces, por otro, constituyen criterios de distinción fundamentales entre los elementos de cada uno de los grupos estudiados.
Su ve Arazi Tabanlı Rekreasyon Olanaklarının Belirlenmesi: Ankara Güneyi Alt Havzası Örneği
Authors: BAYLAN Emel , DİLAVER Zuhal , DEMİR Ayşe , OKTAY Ekin
Published: December 2018

Water
and Land Recreation Opportunity Spectrum (WALROS), stands out as a tool that
guides the institutions responsible for recreation planning and management in determining
recreation opportunities and making decisions on the sustainability of
recreation resources. This study aims to identify WALROS classes of the
Southern Sub-Basin of Ankara Province, where the
population density and urban sprawl put pressure on the natural and rural
resources in the urban fringe and there is a day by day growing demand for
recreation use. In this context, the basin is evaluated based on land surveys and the CORINE 2012 land
use/land cover features by the expert group of four landscape
architects under the WALROS
classifications according to physical, social and managerial parameters. In
order to identify WALROS classes; data collection, preparing the specified
setting parameters for analysis, analysis, classification, weighting and
overlay operations have been implemented in ArcGIS10.2. As a result, the basin
is determined under the classifications of developed-rural, urban and sub-urban
in terms of physical setting parameters. In general, the basin also determined
as natural-rural and developed-rural based on social setting features and
primitive based on managerial features. After overlaid by weighting of each
parameter, semi-primitive class is ranked as the first in terms of areal size, natural-rural class is the second and primitive
class ranked as the third in the basin. Consequently, the basin has the potential to respond to
different recreation needs and experience demands with different recreation
ambient properties and facilities which vary from primitive to urban. For the sustainability of the area’s recreation opportunities,
primitive, semi-primitive and natural-rural class areas must be protected.
Accordingly, limiting visitor intensity in existing recreational areas and
instead of urban characterized recreational activities, ecotourism, rural
tourism or nature conservation activities need to be encouraged in the South Sub-Basin of Ankara
Province.
Kültivatörün Toprak Yüzeyindeki Maddeleri Toprağa Karıştırma Yeteneğinin Bilgisayar Simülasyonu Kullanılarak Geliştirilmesine Yönelik Bir Çalışma
Authors: ÜÇGÜL Mustafa
Published: December 2018

İşçilik maliyetlerinin
yüksek ve toprağın organik madde miktarının düşük olduğu ülkelerde, toprak
üzerine serpilen gübre ve diğer organik maddelerin toprağın alt katmanlarına
hızlı ve ekonomik bir şekilde karıştırılması amacı ile, işletme maliyetleri diğer
tarım aletlerine göre daha düşük olan, kültivatörler kullanılabilir.
Kültivatörün organik maddeyi toprağa hangi oranda karıştırdığı ve bu karışım
miktarının değişik hız ve toprak işleme derinliklerinde nasıl değiştiğinin
deneysel olarak araştırılması zaman alıcı ve maliyetli bir işlemdir. Bu nedenle
bu çalışmada kültivatörün toprak üzerine serpilen organik maddeleri toprağa ne
derece karıştırdığı, ayrık elemanlar metodu kullanılarak, bilgisayar ortamında,
simüle edilmiştir. Ayrıca kültivatörün üzerine ek levhalar eklenerek karıştırma
miktarındaki değişim incelenmiştir. Bunlara ek olarak kültivatör üzerine etki
eden çeki ve dikey kuvvetler incelenmiştir. Çalışmanın sonuçları ek levha
kullanılarak toprağın alt katmanlarına karıştırılacak organik madde miktarının
artırılabileceğini, fakat bu durumda çeki kuvvetinin artacağını göstermiştir.
Çalışmanın sonuçları ayrık elemanlar metodunun tarım makineleri tasarımında
etkili bir hızlı modelleme aracı olarak kullanılabileceğini göstermiştir.
Türkiye’de Domates Üretimi, Dış Ticareti ve Rekabet Gücü
Authors: GÜVENÇ İsmail
Published: December 2018

Bu
çalışmada Türkiye’de toplam sebze üretiminde önemli paya sahip olan domatesin
üretimi, dış ticareti ve rekabet gücü incelenmiştir.  Türkiye’de 2017 verilerine göre 30 milyon
tondan daha fazla sebze üretilmiştir. Toplam sebze üretiminin yaklaşık olarak %
40-45’ini domates oluşturmaktadır. Dünya domates üretiminin % 7.2’i Türkiye’de
üretilmektedir. Türkiye domates üretiminin yıllara göre az çok farklılıklar
olmakla birlikte % 68-72’i açıkta, % 28-32’i ise örtüaltında yapılmaktadır.
toplam sebze ihracatımız sırasıyla 1.076,9 ve 1.268,0 bin ton olarak gerçekleştirilmiştir.
Bu verilere göre toplam sebze üretim miktarımızın % 4 kadarı ihracatta
değerlendirilmektedir. Türkiye’nin toplam taze sebze ihracatı yaklaşık olarak
1,1 milyon ton'dur.  Bu verilere göre
Türkiye’nin toplam sebze üretiminin % 4 kadarı ihraç edilmektedir. Diğer yandan
ülkemiz domates ihracatında avantaja ve rekabet gücüne sahiptir.
Doğu Akdeniz Bölgesi’nde Sera Alanında Çilek Yaprak Nematodu (Aphelenchoides fragariae) (Nemata: Aphelenchida)’nun Tespiti
Authors: ÖZARSLANDAN Adem
Published: December 2018

Aphelenchoides fragariae çilek bitkisinin en önemli bir zararlısı ve çilek fidesi üretiminde de en sık karşılaşılan sorunların başında gelmektedir. 2015 yılında Adana’da saksılı çilek satışı için üretim yapan seradan alınan örnekte nematod analizi yapılmıştır. Çilek yaprakları küçük parçalara ayrılarak Geliştirilmiş Baermann huni yöntemine göre nematodlar elde edilmiştir. Elde edilen nematodların dişi ve larvaların morfolojik analizine göre A. fragariae olduğu tespit edilmiştir. Bu nematodun yapraklarda suya batırılmış gibi bir simptom oluşturmuş olduğu gözlenmiştir. Akdeniz Bölgesi’nde açıkta yetişen çilek alanlarında damlama sulama sisteminin kullanılması ve düzenli yağışın olmaması ilgili nematod için ciddi bir sorun teşkil etmemektedir. Ancak, özellikle çatı yüksekliği standartlara uygun olmayan (engin olan) ve havalandırma sisteminin yetersiz olduğu sera alanlarında çilek bitkisinin yapraklarında bulunan nem tabakası nedeniyle bu zararlının potansiyel olarak sorun oluşturma olasılığı bulunmaktadır.
Antioxidant Properties of Primula vulgaris Flower Extract and Its Cytotoxic Effect on Human Cancer Cell Lines
Authors: DEMİR Selim , TURAN İbrahim , ALİYAZICIOĞLU Yüksel
Published: December 2018

Primula
vulgaris is a plant belonging to Primula
genus, and these species are often used in traditional therapy. Although there
are numerous studies on the antioxidant and cytotoxic effects of different Primula species, there are limited
studies of these properties of P.
vulgaris extracts. The aim of this study was to determine the antioxidant
properties and cytotoxic effects of the extract prepared with dimethyl sulfoxide
from P. vulgaris flowers. The total
phenolic content, total flavonoid content, and reducing antioxidant power of
the extract were determined using spectrophotometric methods. The cytotoxic
effect of the extract on human colon (WiDr), lung (A549), liver (HepG2), breast
(MCF-7), and prostate (PC-3) cancer cells and a normal human fibroblast cell
line was assessed using the MTT assay. Total phenolic content and reducing
power values of extract were found 33.02±0.92 mg gallic acid equivalents, and
64.86±1.18 mg trolox equivalents per g sample, respectively. Extract exhibited
selective cytotoxic effect on all studied cancer cells compared to normal
fibroblast cells, and the IC50 values of the extract in the cancer
cell lines range from 191.8 to 375.3 μg/mL. This work is one of the pioneering
work that reveals the powerful antioxidant properties of P. vulgaris flower extract and its selective cytotoxic effect on
cancer cell lines. Further studies are needed to identify the active molecules
in the extract and the cytotoxic action mechanisms of these molecules.
Revolução Russa e livros didáticos: mais motivos para lamentar do que para celebrar
Authors: Silva Jane Santos da , Faria Lair Amaro dos Santos
Published: December 2018

O ano de 2017 marca o centenário da Revolução Russa e é de se esperar que a data seja comemorada ao redor do mundo. Imaginando que alunos poderiam interessar-se sobre o assunto, os autores resolveram fazer um levantamento sobre a apresentação da Revolução em livros didáticos dos segmentos Fundamental e Médio. O objetivo central foi identificar acertos e incorreções à luz da historiografia especializada e destacar o viés ideológico subjacente ao material pesquisado. A metodologia consistiu em, primeiramente, entabular um breve apanhado da historiografia e, em seguida, detalhar a escrita sobre a Revolução em três livros didáticos – sendo um voltado para o Ensino Fundamental e dois para o Ensino Médio. Como conclusão, os autores reconhecem que os livros didáticos selecionados oferecem mais motivos para lamentar do que para celebrar a Revolução de 1917.Palavras-chave: Ensino de História, Livro Didático, Revolução Russa Russian Revolution and textbooks: more reason to mourn than to celebrateAbstractThe year 2017 marks the centenary of the Russian Revolution and it is to be expected that the date will be celebrated around the world. Imagining that students might be interested in the subject, the authors decided to make a survey about the presentation of the Revolution in textbooks of the Fundamental and Middle segments. The central objective was to identify correctness and inaccuracies in the light of specialized historiography and to highlight the ideological bias underlying the researched material. The methodology consisted in, firstly, a brief survey of historiography and then detailing the writing about the Revolution in three textbooks - one focused on Elementary School and two on High School. In conclusion, the authors acknowledge that the selected textbooks offer more motives to mourn than to celebrate the 1917 Revolution.Keywords: History textbook, Russian Revolution, History Teaching Revolución Rusa y libros de texto: más razones para llorar que para celebrarResumenPara el año 2017 se cumple el centenario de la Revolución Rusa y se espera que la fecha se celebra en todo el mundo. Imaginando que los estudiantes podrían estar interesados en el tema, los autores decidieron hacer una encuesta de la Revolución de la presentación de los libros de texto de los segmentos primarios y secundarios. El principal objetivo fue identificar los éxitos y las imprecisiones a la luz de la historiografía especializada y resaltar el sesgo ideológico subyacente al material investigado. La metodología consistió, en primer lugar, hacer un breve resumen de la historiografía y, a continuación detalladamente la escritura en la Revolución en tres libros de texto - y uno se enfrenta la primaria y dos para la escuela secundaria. En conclusión, los autores reconocen que los libros de texto seleccionados ofrecen más razones para llorar que celebrar la revolución de 1917.Palabras clave: Libro de texto, Enseñanza de la Historia, Revolución Rusa
Ergenlerin Değer Yönelimleri ve Değer Yönelimlerinin İnternet Bağımlılığıyla İlişkisinin İncelenmesi
Authors: DOĞAN Mebrure
Published: December 2018

Araştırmanın amacı ergenlerin
hayatlarında hangi değerlerin etkisini daha çok hissettiklerini, çeşitli
değişkenlerin değer tercihlerinde değişikliğe yol açıp açmadığını ortaya
koymaktır. Ergenlerin internet bağımlılığı düzeyleri ile değer yönelimleri arasındaki
ilişkileri incelemek araştırmanın diğer bir amacını oluşturmaktadır. Ülkemizde
ergenlerin değer yönelimlerinin internet bağımlılığı ile ilişkisini ele alan
bir çalışmaya rastlanmamıştır. Hangi değerlerin ergenler üzerinde daha etkili
olduğunu ve bunların internet bağımlılığı ile ilişkisini incelenmesinin
internet bağımlılığını önleme çalışmalarına yardımcı olacağı düşünülmektedir.
Afyonkarahisar ilinde bulunan beş farklı lisede öğrenim görmekte olan 134’ü kız
(% 48,6), 142’si erkek (% 51,4) olmak üzere 276 lise öğrencisinin katıldığı
çalışmada veriler, “Schwartz Değerler Ölçeği “ ve “Young İnternet Bağımlılığı
Testi Kısa Formu” ile toplanmıştır.  
T-testi, One way ANOVA, Pearson Momentler Çarpım Korelasyon tekniğinin
kullanıldığı araştırmada elde edilen bulgulara göre cinsiyet açısından erkek
öğrenciler “güç, hazcılık ve uyarılım” değerlerini, kız öğrenciler ise
“evrensellik, uyma”  değerlerini daha
fazla önemsemektedirler. Örneklem grubunun değer sıralaması “dindarlık,
iyilikseverlik, güvenlik, öz-yönelim, evrensellik, uyma, başarı, geleneksellik,
uyarılım, güç, hazcılık” şeklinde belirlenmiştir. Araştırmada internet
bağımlılığı ile “güç, hazcılık, uyarılım” değerleri arasında pozitif;
“evrensellik, iyilikseverlik, geleneksellik, uyma ve dindarlık” değerleri
arasında ise negatif yönlü anlamlı ilişkiler tespit edilmiştir.
Öğrenme Güçlüğü Yaşayan Çocuklarda ve Ebeveynlerinde Yaşam Kalitesi
Authors: SAKIZ Halis , BAŞ Güldest
Published: December 2018

Bu araştırmanın amacı, öğrenme güçlüğü ile tanılanmış çocukların ve
ebeveynlerinin yaşam kalitesi düzeylerini incelemektir. Araştırmada 120 çocuk
ve 120 ebeveynin yaşam kalitesi sırasıyla Çocuklar İçin Genel Amaçlı Sağlıkla
İlgili Yaşam Kalitesi Ölçeği (KINDL-R-Kid) ve Dünya Sağlık Örgütü Yaşam Kalitesi
Ölçeği-Kısa Formu Türkçe Versiyonu (WHOQOL-BREF-TR) ile ölçülmüş olup; yaşam
kalitesi düzeyleri ve bu düzeyler arasındaki ilişki ile çocuk yaşam kalitesinin
ebeveyn yaşam kalitesini ne düzeyde yordadığı betimsel ve çıkarımsal
istatistiksel analiz yöntemleri ile araştırılmıştır. Bulgular, çocuk ve ebeveyn
yaşam kalitesi arasında anlamlı ilişkiler olduğunu ve çocuk yaşam kalitesinin
ebeveyn yaşam kalitesini anlamlı düzeyde yordadığını göstermiştir. Elde edilen
sonuçlardan yola çıkılarak öğrenme güçlüğüne dair psiko-sosyal ve psiko-eğitsel
hizmetler geliştirilirken, başta aile olmak üzere sistem içinde yer alan tüm
unsurların dikkate alınması gerektiğini göstermektedir.
DESENVOLVIMENTO DE SISTEMA WEB E DESKTOP PARA CONTROLE DE PRESENÇA UTILIZANDO A BIOMETRIA
Authors: Lourenço martins Igor rafael , Cardoso de Oliveira Frank Willian
Published: December 2018

Em eventos onde se é preciso confirmar a presença de um indivíduo, se faz necessária a verificação da sua identidade. Pensando nisso, o Sistema de Gestão de Presença com Biometria (SGPB) foi desenvolvido com o foco na utilização da biometria para o controle de presença de alunos e servidores do Instituto Federal do Paraná campus de Paranavaí em eventos realizados pelo mesmo. Este artigo apresenta um sistema de controle de presença através da impressão digital, utilizando leitor biométrico com sensor óptico, estruturado em módulos desktop e web, e desenvolvido aplicando tecnologias atuais tais como a Linguagem Java, os frameworks Spring Security, Maven, Hibernate e Java ServerFaces.
DISPENSADOR DE MEDICAMENTOS AUTOMATIZADO
Authors: Junior Jamilson Gomes Moreira , Flôr Daniela Eloíse
Published: December 2018

Este trabalho apresenta um protótipo de um dispensador de medicamentos com funções automatizadas para auxiliar idosos usuários de múltiplos medicamentos a tomarem suas doses em dia. A metodologia consistiu nas fases de geração do conceito, projeto preliminar e projeto detalhado. O resultado obtido foi um protótipo que atende à maior parte dos requisitos do projeto.
KLOSS: FERRAMENTA GRÁFICA PARA O ENSINO DE ALGORITMOS DE ORDENAÇÃO
Authors: Johansson Karina Mayumi , Flor Daniela Eloise
Published: December 2018

A literatura relata dificuldades encontradas no processo de ensino-aprendizagem da disciplina de Algoritmo e Estrutura de Dados (AED). Fatores complicadores apontados são: o ensino da disciplina logo no início do curso e a exigência de capacidades dos alunos, como: alto nível de abstração, pensamento crítico, base matemática e lógica; habilidades que muitas vezes não foram desenvolvidas em anos anteriores de estudo. Uma proposta para tentar minimizar esse problema é a utilização de ferramentas gráficas de apoio. No contexto nacional do ensino da disciplina AED, a metodologia tem obtido resultados positivos. Um ponto observado sobre as ferramentas existentes é que elas ilustram os diversos métodos de ordenação de vetores de modo genérico, independemente de suas particularidades. Deste modo, este trabalho tem como objetivo apresentar Kloss, uma ferramenta gráfica para o ensino de algoritmos de ordenação desenvolvida no ambiente Scratch. A ferramenta apresenta as animações dos métodos Bubble Sort, Insertion Sort e Quick Sort. Kloss foi empregada no ensino do conteúdo, na disciplina Algoritmos e Linguagem de Programação II, em um Curso Técnico em Informática Integrado ao Ensino Médio. A partir dessa utilização, foi feita uma avaliação quantitativa de Kloss, que obteve como resultados aproximadamente 80% de aceitação nos quesitos interface gráfica e usabilidade.