bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Structure—Activity Relationship of a Series of Diaminoalkyl Substituted Benzimidazole (I) as Neuropeptide Y Y1 Receptor Antagonists.
Authors: Zarrinmayeh Hamideh , Zimmerman Dennis M. , Cantrell Buddy E. , Schober Douglas A. , Bruns Robert F. , Gackenheimer Susan L. , Ornstein Paul L. , Hipskind Philip A. , Britton Thomas C. , Gehlert Donald R.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Formation of Enantiopure β‐Amino Alcohols with a 3‐Oxa‐2,7‐diazabicyclo[3.3.0]octane Framework.
Authors: Aurich Hans Guenter , Soeberdt Michael , Harms Klaus
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Acylation of 4‐Amino‐4,5‐dihydro‐1H‐1,2,4‐triazol‐5‐ones.
Authors: Ikizler Aysun , Dogan Nese , Ikizler Aykut A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses of Various Imidazo[5,1‐c][1,2,4]triazole Derivatives Having Potential Biological Activities.
Authors: Ismail Mohamed Abdel Hamid
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel and Efficient Method for the Synthesis of N‐Arylsulfonylamino‐2‐pyridones.
Authors: Elgemeie Galal H. , Elghandour Ahmed H. H. , Ali Hosny A. , Abdel‐Azzez Hassan M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Methylenation and Oxidation of Chiral Non‐Racemic 2‐Piperidones: Reactivity of a New 3‐Oxolactam.
Authors: Forns Pilar , Fernandez M. Montserrat , Diez Anna , Rubiralta Mario , Cherrier Marie Pierre , Bonin Martine , Quirion Jean‐Charles
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Antitumor Activity of Javacarboline Derivatives.
Authors: Yoshino Hiroshi , Koike Kazuo , Nikaido Tamotsu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aromatic Nucleophilic N—N Exchange Reaction of N,N‐Dimethyl‐5,7‐bis(trifluoroacetyl)‐8‐quinolylamine with Various Amines: A Facile Synthetic Method for 5,7‐Bis(trifluoroacetyl)‐8‐quinolylamines.
Authors: Okada Etsuji , Tsukushi Norikado
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Addition of Chiral (2‐Lithiophenyl)acetaldehyde Acetals to Various Imines as Key Step in the Asymmetric Synthesis of 1‐Aryltetrahydroisoquinolines. Part 4.
Authors: Wuensch Bernhard , Nerdinger Sven
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of Polyfunctionally Substituted 2′,2′‐Bis(ethoxycarbonyl)methylene‐5′‐methoxycarbonyl(cyano)spiro [dihydroacridine‐9(10H),4′‐thiazolidines].
Authors: Bernat Juraj , Chomca Igor , Kristian Pavol , Pihlaja Kalevi , Klika Karl Douglas , Imrich Jan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: General Synthetic Method for Naphthyridines and Their N‐Oxides Containing Isoquinolinic Nitrogen.
Authors: Numata Atsushi , Kondo Yoshinori , Sakamoto Takao
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Expeditious Synthesis of 4‐Acyl‐2,6‐dioxo‐1,2,3,6‐tetrahydropyrimidines (6‐Acyl uracils) and 4‐Acyl‐6‐aryl‐2‐oxo‐2,3‐dihydropyrimidines.
Authors: Khan M. Wahab , Kundu Nitya G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Mild Method for the Preparation of 8‐Substituted Xanthines from 5,6‐Diaminouracils.
Authors: de Araujo Aline D. , Bacher Edmond , Demnitz F. W. Joachim , Santos Douglas A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 4‐Amino‐6‐benzylamino‐1,2‐dihydro‐2‐phenyl‐1,2,4‐triazolo [4,3‐a]quinoxalin‐1‐one: A New A2A Adenosine Receptor Antagonist with High Selectivity versus A1 Receptors.
Authors: Colotta Vittoria , Catarzi Daniela , Varano Flavia , Cecchi Lucia , Filacchioni Guido , Martini Claudia , Trincavelli Letizia , Lucacchini Antonio
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Fremy′s Salt‐Mediated Oxidation and Rearrangement of Anilines into Amino ortho‐Diketones. Applications to the Synthesis of Pyrrolobenzodiazepines.
Authors: Kraus George A. , Selvakumar Natesan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Polycondensed Heterocycles. Part 10. A New Method for the Preparation of Pyrrolo[2,1‐c][1,4]benzothiazepines by Intramolecular Mitsunobu Cyclization.
Authors: Garofalo Antonio , Campiani Giuseppe , Fiorini Isabella , Nacci Vito
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Method for Preparation of Chiral Macrocyclic Bisamides Starting from Diol Derivatives of D‐Mannitol and L‐Tartaric Acid.
Authors: Gryko Daniel T. , Piatek Piotr , Jurczak Janusz
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Reaction of the α‐Selenium Stabilized Copper Reagents ArSeCH2Cu(CN)ZnCl with Aldehydes.
Authors: Duan De‐Hui , Huang Xian
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis of Oxygenated Naphthyl Stannanes Possessing ortho‐Methoxy Substituents for Use in Stille Coupling Reactions.
Authors: Brimble Margaret A. , Duncalf Letecia J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Diterpenoids from Acacia decurrens (Fabaceae).
Authors: Anam Edet M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (.+‐.)‐Pedicularis‐Lactone and (.+‐.)‐Ningpogenin.
Authors: Lee An‐Yang , Chang Meng‐Yang , Chang Nein‐Chen
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Antimicrobial and Cytotoxic Activity of Sesquiterpene Quinones (I)—(III) and Brominated Diphenyl Ethers (IV), (V), Isolated from Marine Sponges.
Authors: Popov A. M. , Stekhova S. I. , Utkina N. K. , Rebachuk N. M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Regioselective Synthesis of 24‐epi‐Pterosterone.
Authors: Suksamrarn Apichart , Yingyongnarongkul Boon‐ek , Charoensuk Siritorn
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Micropeptin T‐20, a Novel Phosphate‐Containing Cyclic Depsipetide from the Cyanobacterium Microcystis aeruginosa
Authors: Okano Tomoki , Sano Tomoharu , Kaya Kunimitsu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Activity of γ‐(L‐γ‐Azaglutamyl)‐S‐(p‐bromobenzyl)‐L‐cysteinylglycine: A Metabolically Stable Inhibitor of Glyoxalase I.
Authors: Vince Robert , Brownell Jay , Akella Lakshmi B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The 2‐N,N‐Dibenzylamino Group as a Participating Group in the Synthesis of β‐Glycosides.
Authors: Jiao Hailong , Hindsgaul Ole
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reversible Generation of Glycosyl Radicals from Telluroglycosides under Photochemical and Thermal Conditions.
Authors: Yamago Shigeru , Miyazoe Hiroshi , Yoshida Jun‐ichi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Vinylic C‐Glycosides from Telluroglycosides. Addition of Photochemically and Thermally Generated Glycosyl Radicals to Alkynes.
Authors: Yamago Shigeru , Miyazoe Hiroshi , Yoshida Jun‐ichi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Radical‐Mediated Imidoylation of Telluroglycosides. Insertion of Isonitriles into the Glycosidic Carbon—Tellurium Bond.
Authors: Yamago Shigeru , Miyazoe Hiroshi , Goto Ryuta , Yoshida Jun‐ichi
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Complete Regioselectivity in Staurosporine Chromophore Formation.
Authors: Eils Stefan , Winterfeldt Ekkehard
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iminophosphorane‐Mediated Synthesis of the Alkaloid Cryptotackieine.
Authors: Molina P. , Fresneda P. M. , Delgado S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (‐)‐Strychnine via the Wieland—Gumlich Aldehyde.
Authors: Sole Daniel , Bonjoch Josep , Garcia‐Rubio Silvina , Peidro Emma , Bosch Joan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Synthesis of Febrifugine and Isofebrifugine.
Authors: Kobayashi Shu , Ueno Masaharu , Suzuki Ritsu , Ishitani Haruro
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dippinine C, a New Hexacyclic Chippiine Derivative from a Malayan Tabernaemontana.
Authors: Kam Toh‐Seok , Sim Kooi‐Mow
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isoharmine Revisited: Thermal Rearrangement of a 3‐Cyanomethyl‐2‐vinylindole.
Authors: Sapi Janos , Patigny Dominique , Laronze Jean‐Yves
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of 2′‐Amino‐2′,3′‐dideoxynucleosides by Nitrone 1,3‐Dipolar Cycloaddition: A New Efficient Entry Toward d4T and Its 2‐Methyl Analogue.
Authors: Chiecchio Ugo , Rescifina Antonio , Iannazzo Daniela , Romeo Giovanni
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Absolute Configuration of Amphidinol 3 (I), the First Complete Structure Determination from Amphidinol Homologues: Application of a New Configuration Analysis Based on Carbon—Hydrogen Spin‐Coupling Constants.
Authors: Murata Michio , Matsuoka Shigeru , Matsumori Nobuaki , Paul Gopal K. , Tachibana Kazuo
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Anthraquinone Derivative from Cassia fistula Linn. Pods.
Authors: Rani Meena , Kalidhar S. B.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ellagic Acid Derivatives from the Leaves of Eugenia jambos Linn.
Authors: Chakravarty Ajit Kumar , Das Binayak , Sarkar Tapas , Masuda Kazuo , Shiojima Kenji
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Electrochemical Study of a New Chiral Tris‐catecholamide Analogue of Enterobactin.
Authors: Cheraiti N. , Brik M. E. , Gaudemer A. , Kunesh G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Studies Toward Phorboxazole A. Stereoselective Synthesis of the C3—C19 and C20—C32 Subunits.
Authors: Williams David R. , Clark Michael P. , Berliner Martin A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Macrocyclic Domain of Phorboxazole A. A Stereoselective Synthesis of the C1—C32 Macrolactone.
Authors: Williams David R. , Clark Michael P.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Properties of 2‐(Naphthosultamyl)methyl‐carbapenems with Potent anti‐MRSA Activity: Discovery of L‐786,392.
Authors: Ratcliffe R. W. , et al. et al.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bioactive Marine Metabolites. Part 90. Octa‐ and Nonaprenylhydroquinone Sulfates, Inhibitors of α1,3‐Fucosyltransferase VII, from an Australian Marine Sponge Sarcotragus sp.
Authors: Wakimoto Toshiyuki , Maruyama Atsushi , Matsunaga Shigeki , Fusetani Nobuhiro , Shinoda Katsumi , Murphy Peter T.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Titanium Phosphate Glass‐Ceramics with Silver Ion Exchangeability.
Authors: Kasuga Toshihiro , Nogami Masayuki , Abe Yoshihiro
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Manganese Oxide Porous Crystals
Authors: Feng Qi , Kanoh Hirofumi , Ooi Kenta
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Transformation of Ecdysteroids: Latest Advances
Authors: Kovganko N. V.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Withanolides, Biologically Active Natural Steroidal Lactones: A Review
Authors: Anjaneyulu A. S. R. , Rao D. S. , Lequesne P. W.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selectivity in Thermodynamic Cyclizations of Cinchona Alkaloid Derivatives
Authors: Rowan S. J. , Brady P. A. , Sanders J. K. M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of Naphthylisoquinoline Alkaloids
Authors: Rizzacasa Mark A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Methylcyclopentanoid Monoterpenes
Authors: Bianco A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Studies on the Optically Active Diels—Alder‐Type Adducts from Mulberry Tree
Authors: Nomura Taro , Hano Yoshio , Ueda S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cross‐Metathesis
Authors: Gibson Susan E. , Keen Stephen P.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Selenazines and Benzoselenazines
Authors: Sainsbury M.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxonium Ion Initiated Pinacolic Ring Expansion Reactions
Authors: Paquette Leo A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Supramolecular Synthesis of Organic and Metal‐Organic Laminates with Affinity for Aromatic Guests: Hydrophobic Clay Mimics
Authors: Biradha Kumar , Dennis Dorothy , Mackinnon Verna A. , Seward Corey , Zaworotko Michael J.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Applications of Chiral Sulfoximines to Diastereoselective and Catalytic Asymmetric Synthesis
Authors: Pyne Stephen G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: N‐Alkylidenesulfinamides
Authors: Hua Duy H. , Chen Yi , Millward Gail S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Designer Lewis Acids for Selective Organic Synthesis
Authors: Yamamoto Hisashi , Yanagisawa Akira , Ishihara Kazuaki , Saito Susumu
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Supramolecular Chemistry
Authors: Cantrill S. J. , Fyfe M. C. T. , Raymo F. M. , Stoddart J. F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Resins and Linkers for Solid‐Phase Synthesis of Small Molecules
Authors: Blackburn Christopher , Albericio Fernando , Kates Steven A.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enaminones: Useful Starting Materials for the Preparation of Heterocycles
Authors: Cimarelli Cristina , Palmieri Gianni
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Improvements for the Preparation and Synthetic Applications of β‐Nitroenones
Authors: Schneider Raphael , Gerardin Philippe , Ahrach Mohammed , Boelle Jerome , Loubinoux Bernard
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Properties of Resin Supports and Their Effects on Solid‐Phase Organic Synthesis
Authors: Yan Bing
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: RPR′s Approach to High‐Speed Parallel Synthesis for Lead Generation
Authors: Labaudiniere Richard F.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 1‐Hydroxyindoles
Authors: Somei Masanori
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cadmium Therapeutic Agents
Authors: Kelley Colleen , Sargent David E. , Uno Jennifer K.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Concepts in Directed Biaryl Synthesis. Part 78. The Lactone Concept: An Efficient Pathway to Axially Chiral Natural Products and Useful Reagents
Authors: Bringmann Gerhard , Breuning Matthias , Tasler Stefan
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reductive Amination of Oxygen‐Containing Organic Compounds
Authors: Tarasevich V. A. , Kozlov N. G.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Levulinic acid in Organic Synthesis
Authors: Timokhin B. V. , Baransky V. A. , Eliseeva G. D.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chiral 3,6‐Dihydro‐2H‐1,4‐oxazin‐2‐ones as Alanine Equivalents for the Asymmetric Synthesis of α‐Methyl α‐Amino Acids (AMAAs) under Mild Reaction Conditions
Authors: Chinchilla Rafael , Galindo Nuria , Najera Carmen
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Models of Protein β‐Sheets
Authors: Nowick James S.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 3′‐C‐ and 4′‐C‐Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)
Authors: Wengel Jesper
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spiroepoxycyclohexa‐2,4‐dienones in Organic Synthesis
Authors: Singh Vishwakarma
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthetic and Structural Chemistry of Heme Derivatives with Nitric Oxide Ligands
Authors: Scheidt W. Robert , Ellison Mary K.
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Separation and Analysis of Saccharides — On Mainly Oligosaccharides
Authors: Koizumi Kyoko
Published: June 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cell‐Selective, Apoptosis‐inducing Rhodium(III) Crown Thiaether Complexes
Authors: Bieda Ruth , Dobroschke Mara , Triller Annika , Ott Ingo , Spehr Marc , Gust Ronald , Prokop Aram , Sheldrick William S.
Published: June 2010

Half‐sandwich rhodium(III) polypyridyl (pp) complexes with the metal atom capped by the facial crown thiaether 1,4,7‐trithiacyclononane [9]aneS3 represent a promising class of apoptosis‐inducing potent cytostatic agents. The necrotic damage caused by the complexes is negligible. In vitro cytotoxicity assays with the human cancer cell lines MCF‐7 and HT‐29 and immortalized HEK‐293 cells indicate that the dicationic κ2N(imino) complexes [([9]aneS3)RhCl(pp)]2+ are much more active than monocationic complexes [([9]aneS3)RhCl2(L)]+ (L=imidazole, CH3CN). Whereas the κ2N(amino) complex [([9]aneS3)RhCl(piperazine)]2+ is inactive, replacing piperazine with the structurally analogous κ2S (thiaether) ligand 1,4‐dithiane restores cytotoxicity as evidenced by IC50 values in the range 8.1‐11.6 μM. Spectroscopic (CD, UV/Vis, NOESY) and viscosity measurements indicate that the active dppz complex 8 (IC50 values: 4.7–8.9 μM) exhibits strong intercalative binding towards DNA whereas the even more potent bipyrimidine complex 9 (IC50 values: 0.6–1.9 μM) causes no alteration of the duplex B conformation. Weaker intercalative binding is observed for the dpq complex 7. A comparative annexin V–propidium iodide binding assay with lymphoma (BJAB) cells and healthy leukocytes demonstrates that the cytotoxic activity of complex 8 and particularly complex 9 is highly selective towards the malignant cells.
Predictors of anticoagulation in hospice patients with lung cancer
Authors: Holmes Holly M. , Bain Kevin T. , Zalpour Ali , Luo Ruili , Bruera Eduardo , Goodwin James S.
Published: June 2010

BACKGROUND:

Guidelines recommend lifelong anticoagulation in patients with cancer and a history of thromboembolism, but the use of anticoagulation in hospice has not been described. A retrospective study of medication data was conducted to determine patterns of anticoagulant use and predictors of type of anticoagulant prescribed for hospice patients with lung cancer.

METHODS:

Medication data were evaluated for 16,896 hospice patients with lung cancer in 2006 to determine patient and hospice characteristics that predicted anticoagulant prescription. Independent predictors of warfarin versus low molecular weight heparin (LMWH) prescription were identified using a logistic regression model.

RESULTS:

One of every 11 patients was prescribed an anticoagulant, most commonly warfarin. Compared with patients prescribed LMWH, patients prescribed warfarin were older (71.6 vs 65.8 years, P<.001), were more likely white (81.2% vs 74.3%, P = .03), had a longer stay in hospice (median 21 days vs 17 days, P = .001), and were more likely to have ≥3 comorbid illnesses (37.5% vs 25.0%, P<.001). The strongest independent predictor of type of anticoagulant prescribed was geographic region, with hospices in the Northeast more likely to prescribe LMWH.

CONCLUSIONS:

Anticoagulant use is prevalent in patients with lung cancer enrolled in hospice. This study highlights the need to understand the benefits and risks of anticoagulation at the end of life. Cancer 2010. © 2010 American Cancer Society.
Activity and tolerability of nilotinib
Authors: Koren‐Michowitz Maya , le Coutre Philipp , Duyster Justus , Scheid Christof , Panayiotidis Panayiotis , Prejzner Witold , Rowe Jacob M. , Schwarz Michaela , Goldschmidt Neta , Nagler Arnon
Published: June 2010

BACKGROUND:

Nilotinib is active in imatinib‐resistant and ‐intolerant chronic myeloid leukemia patients and was recently approved for these indications.

METHODS:

Data on the efficacy and safety of nilotinib treatment were collected from 2 phase 2 expanded access clinical trials with similar designs (CAMN107AIL01 and ENACT).

RESULTS:

Of 88 study patients (58 chronic, 11 accelerated, 19 blast crisis), the best responses to nilotinib were complete hematologic response (CHR) in 27%, partial cytogenetic response in 12%, complete cytogenetic response in 14%, and major molecular response in 19%. Patients achieving at least a CHR during imatinib therapy were more likely to respond to nilotinib, and failure to achieve at least a CHR on imatinib therapy was predictive of progression or lack of response to nilotinib (P = .0021). Responses were not statistically different in subgroup analysis, including that of imatinib intolerance compared with imatinib resistance, presence of ABL kinase domain mutations compared with absence of mutations, and previous treatment with another second‐generation tyrosine kinase inhibitor compared no prior treatment. The overall survival and progression‐free survival rates at 1 year were 83% and 48% for the entire cohort, 93% and 66% in chronic phase, and 64% and 19% in advanced phase. Adverse hematological events included thrombocytopenia (all events, 27%; grade 3‐4, 13%) and leukopenia (all events, 18%; grade 3‐4, 10%). The majority of the nonhematological events were mild, the most common being rash, infection, bone pain, headache, nausea, and vomiting.

CONCLUSIONS:

Nilotinib treatment is an efficient and safe therapy for imatinib‐resistant or ‐intolerant patients. Prior response to imatinib therapy is a predictor for the response to nilotinib. Cancer 2010. © 2010 American Cancer Society.
Interim report of a phase 2 clinical trial of lenalidomide for T‐cell non‐Hodgkin lymphoma
Authors: Dueck Greg , Chua Neil , Prasad Angeli , Finch Daygen , Stewart Doug , White Darrell , van der Jagt Richard , Johnston James , Belch Andrew , Reiman Tony
Published: June 2010

BACKGROUND:

Novel therapies are needed to improve outcomes in T‐cell lymphomas. The authors report the interim results of a prospective multicenter trial evaluating lenalidomide in T‐cell lymphomas.

METHODS:

Patients with recurrent and refractory T‐cell lymphomas other than mycosis fungoides and untreated patients ineligible for combination chemotherapy were prescribed oral lenalidomide (25 mg daily) on Days 1 to 21 of each 28‐day cycle until disease progression, death, or unacceptable toxicity. The primary endpoint was overall response rate. Secondary endpoints were progression‐free survival (PFS), overall survival (OS), and safety. The 2‐stage design allows for up to 40 patients.

RESULTS:

At the time of this interim analysis, 24 patients were enrolled in this study, and 23 were evaluable for response. The median age was 65 years. The overall response rate was 7 (30%) of 23; all were partial responses. Two patients had stable disease for ≥5 cycles. Responses were seen in anaplastic, angioimmunoblastic, and peripheral T‐cell unspecified histologies. Median PFS was 96 days (range, 8‐696+ days). Median OS was 241 days (range, 8‐696+ days). The most common grade 4 adverse event was thrombocytopenia (33%). The most common grade 3 adverse events were neutropenia (21%), febrile neutropenia (17%), and pain not otherwise specified (17%). Rash correlated with response to therapy (P = .003).

CONCLUSIONS:

In patients with recurrent and refractory T‐cell lymphomas, oral lenalidomide monotherapy has clinical activity, and toxicity is consistent with the known safety profile of lenalidomide. Further study of lenalidomide in these diseases is warranted. Cancer 2010. © 2010 American Cancer Society.
Utility of the GeneSearch breast lymph node assay for the rapid evaluation of sentinel lymph nodes in breast cancer
Authors: Funasako Yawara , Uenosono Yoshikazu , Hirata Munetsugu , Arigami Takaaki , Yanagita Shigehiro , Arima Hideo , Ehi Katsuhiko , Kijima Yuko , Yoshinaka Heiji , Natsugoe Shoji
Published: June 2010

BACKGROUND:

The potential for reducing the need for second surgery for axillary lymph node dissection (ALND) has made the intraoperative evaluation of sentinel lymph nodes (SLNs) attractive. The goal of the current study was to evaluate the clinical application of the breast lymph node (BLN) assay, a real‐time reverse transcriptase‐polymerase chain reaction assay for SLN metastases, by comparing this test with routine pathologic examination.

METHODS:

A total of 117 patients with breast cancer underwent breast surgery with SLN biopsy. Each SLN was cut in half along the plane of the longest dimension. Half of each lymph node was examined by the 2 markers of the BLN assay, mammaglobin and cytokeratin 19, and the other half was examined by hematoxylin and eosin staining (H&E) and immunohistochemical staining (IHC) for pancytokeratins.

RESULTS:

A total of 204 SLNs were obtained from 117 patients. H&E staining identified metastases in 31 SLNs (15.2%), and IHC staining detected metastases in 6 SLNs; 40 SLNs from 32 patients were found to be positive for metastasis using the BLN assay. The assay results were correlated with the pathologic diagnoses by H&E and IHC staining (P <.001). The sensitivity of the BLN assay compared with pathologic findings classified according to the TNM classification was 95.7% for macrometastases, 60.0% for micrometastases, and 55.6% for isolated tumor cells.

CONCLUSIONS:

The 2‐marker BLN assay performs in a manner that is comparable to, and analyzes more tissue than, routine pathologic examination. Therefore, clinical intraoperative use of the BLN assay for SLNs may result in a reduction in the need for second surgery for ALND. Cancer 2010. © 2010 American Cancer Society.