bluuebunny/crossref_metadata_2025 huggingface dataset:
Can gamification affect the advertising effectiveness in social media?
Authors: Tabaeeian Reihaneh Alsadat , Rahgozar Shakiba , Khoshfetrat Atefeh , Saedpanah Samira
Published: December 2023

Purpose

The purpose of this paper is to investigate how gamification in advertising affects the effectiveness of advertising on social media.

Design/methodology/approach

Drawing from the gamification literature, immersion, achievement and social interaction features were identified as features, and advertising effectiveness factors were brand attention, brand liking and recall. A questionnaire was used for collecting data, and a structural equation modeling approach was applied to examine the model.

Findings

The results indicated that immersion, achievement and social interaction features affect advertising effectiveness. Furthermore, advertising effectiveness factors had a significant effect on purchase intentions.

Originality/value

The study contributes to the combination of gamification in advertising by offering characteristics for gamification that can enhance advertising effectiveness through brand attention, liking and recall. Finally, it provides managerial guidance on how they can use gamification in their advertising process.
Investigating ground-related design deficiencies as potential triggers to cost overruns in highway projects
Authors: Amadi Alolote Ibim
Published: December 2023

Purpose

This study aims to investigate ground-related design deficiencies as potential avenues of avoidable cost overruns, discernible from the geotechnical practices of highway agencies in the Niger Delta region of Nigeria.

Design/methodology/approach

The study deploys an interpretivist qualitative methodology to provide a detailed descriptive analysis of the design-related geotechnical practices of highway agencies during the pre-contract phase of highway projects. Semi-structured interviews were conducted with in-house professionals, consultants and contractors affiliated with the three highway agencies in the Niger Delta and thematically analysed to identify significant deviations from geotechnical best practices.

Findings

The study outcome shows that during the pre-contract phase, a chain of design-related geotechnical shortcomings has plagued highway projects executed in the Niger Delta. This view of practice uncovered in this study demonstrates a culture of significant deviation from best practice recommendations, which could plausibly contribute to the history of significant project cost overruns recorded in the region.

Originality/value

The study qualitatively spotlights gaps in the practice of highway agencies and reinforces the need for a re-orientation of the attitude to risk management, to give geotechnical concerns a priority in the financial management of highway projects executed in the Niger Delta region of Nigeria.
Do Instagram reels influence travelers' behavioral and e-WOM intentions for the selection of ecotourism destination?
Authors: Sharma Nidhi , Arora Nilesh
Published: December 2023

Purpose

There has been considerable discussion about the utilization of social media effectively in tourist research. Still, there is a paucity of information about its usage for ecotourism destination selection. The study aims to determine critical factors influencing travelers' behavioral and electronic word-of-mouth (e-WOM) intentions to use Instagram reels to select an ecotourism destination.

Design/methodology/approach

This study is based on the motivated consumer innovativeness theory and technology acceptance model. Purposive sampling was applied to acquire data from Instagram users. Data were gathered from 445 respondents and 415 valid responses were analyzed using partial least square structural equational modeling.

Findings

The findings of the study confirmed the positive impact of perceived ease of use, socially motivated consumer innovativeness and hedonically motivated consumer innovativeness on travelers' attitude except for perceived usefulness. The outcomes also revealed a significant influence of travelers' attitude on behavioral and e-WOM intention.

Research limitations/implications

The study's findings were intended to offer insights into traveler behavior to critical players in the tourism sector, including destination marketers, travel companies, the government and policymakers. They must comprehend how useful Instagram is for the tourist industry, which will help them better understand how to attract travelers through Instagram reels to market their destination.

Originality/value

The current investigation is the first attempt to investigate the travelers' behavioral and e-WOM intentions to use Instagram reels to select an ecotourism destination.
Should I stay or should I go back? Factors influencing snowbirds' permanent relocation intention
Authors: Chaulagain Suja , Li Jianwen , Baniya Rojan , Pizam Abraham
Published: December 2023

Purpose

The objective of the present study was to investigate the impacts of familiarity with and awareness of Florida as a snowbird destination, and satisfaction with the snowbird experience on Florida's image and on snowbirds' permanent relocation intention to Florida. Additionally, the influence of Florida's image on snowbirds' behavioral intention to move to Florida permanently was investigated.

Design/methodology/approach

Data gathered from 304 snowbirds were utilized in employing structural equation modeling to assess the research model.

Findings

The study results showed that awareness of and familiarity with Florida as a snowbird destination, and satisfaction with the snowbird experience significantly influenced participants' image perceptions of Florida. In addition, awareness of and familiarity with Florida as a snowbird destination, and participants' image of Florida had a significant influence on snowbirds' intentions to move to Florida permanently.

Practical implications

The findings of the study provide significant insights for destination marketing and management organizations and local policymakers in formulating and enacting policies in snowbird destinations to efficiently address migration trends.

Originality/value

This study is one of the first papers to empirically investigate and successfully construct a comprehensive model that explicate the determinants of snowbird tourists' permanent relocation intention.
Health care model for people living in nursing homes based on integrated care
Authors: Espaulella-Ferrer Mariona , Morel-Corona Felix Jorge , Zarco-Martinez Mireia , Marty-Perez Alba , Sola-Palacios Raquel , Campollo-Duquela Maria Eugenia , Cruz-Grullon Maricelis , Puigoriol-Juvanteny Emma , Otero-Viñas Marta , Espaulella-Panicot Joan
Published: December 2023

Purpose

Older people living in nursing homes have complex care needs and frequently need specialists’ advice and support that can be challenging to deliver in a rural setting. The aim of this paper is to describe a model of integrated care in a rural area supported by a nurse case manager.

Design/methodology/approach

A real-world evidence study of people living in Ribes de Freser nursing home, was conducted between specific timeframes in 2019 and 2022, comparing the casemix and outcomes of a traditional care model with the integrated interdisciplinary model.

Findings

The integrated care model led to a significant reduction in transfers to the emergency department, hospitalisations, outpatient medical visits and a reduction in the number of medicines. In addition, the number of residents receiving end-of-life care at the nursing home showed a substantial increase.

Originality/value

This case study contributes valuable evidence supporting the implementation of an integrated model of nurse case manager support in nursing homes, particularly in the rural contexts, where access to specialist medical staff may be limited. The findings highlight the potential benefits of person-centred integrated care for older adults, addressing their complex needs and improving end-of-life care in nursing home settings.
The effects of low-carbon awareness on remanufacturing strategy in the presence of competition
Authors: Zheng Yanyan , Liu Peng , Zhao Yingxue , Zhang Zhichao
Published: December 2023

Purpose

This paper examines how the level of low-carbon awareness (LCA) affects the remanufacturing strategy in a supply chain with an original equipment manufacturer (OEM) and an independent remanufacturer (IR) competing with each other.

Design/methodology/approach

Game theory and operations optimization.

Findings

The studies analytically characterize the threshold levels of the LCA in response to which the OEM and the IR will change their remanufacturing strategies from no remanufacturing to partial remanufacturing and then to full remanufacturing. In addition, the studies reveal that as compared with the OEM, the IR has more flexibility in terms of the market entry to remanufacturing with the level of LCA increasing. With the extended studies, it is exhibited that the above findings are robust to a good extent.

Originality/value

It can provide decision support for remanufacturing enterprises.
Connecting differential psychological motivations for WeChat use with civic engagement: the significant role of bonding and bridging social capital
Authors: Pang Hua
Published: December 2023

Purpose

The primary objectives of this article are to systematically explore whether and how certain WeChat use motives could lead to bridging social capital, bonding social capital and civic engagement among young people.

Design/methodology/approach

The data was collected from a large-scale online survey of 1208 young people in mainland China. Zero-order correlation analyses and structural equation modeling were carried out to examine the corresponding hypotheses.

Findings

Obtained findings show that WeChat use for informational and social motivations are positively associated with bonding and bridging social capital. Moreover, bonding social capital could mediate the relationship between WeChat usage for informational and relational motivations and civic engagement.

Research limitations/implications

Theoretically, this article underlines the unique social and technological affordances of WeChat by exploring mobile social media use and how it would contribute to the quality of democracy by fostering young people's engagement in civic life. Practically, bridging and bonding social capital play significant roles in enhancing young people's civic engagement, which could be the meaningful resource for mobile social media designers, managers and government officials.

Originality/value

These obtained outcomes underlined the vital role of these newly emerging communication technologies in fostering democratic involvement and production of social capital in contemporary socially networked society.
Stakeholder participation in the ISSB’s standard-setting process: the consultations on the first exposure drafts on sustainability reporting
Authors: Kulik Alessandra , Dobler Michael
Published: December 2023

Purpose

This paper aims to provide empirical evidence on formal stakeholder participation (or “lobbying”) in the early phase of the International Sustainability Standards Board’s (ISSB’s) standard-setting.

Design/methodology/approach

Drawing on a rational-choice framework, this paper conducts a content analysis of comment letters (CLs) submitted to the ISSB in response to its first two exposure drafts (published in 2022) to investigate stakeholder participation across different groups and jurisdictional origins. The analyses examine participation in terms of frequency (measured using the number of participating stakeholders) and intensity (measured using the length of CLs).

Findings

Preparers and users of sustainability reports emerge as the largest participating stakeholder groups, while the accounting/sustainability profession participates with high average intensity. Surprisingly, preparers do not outweigh users in terms of participation frequency and intensity; and large preparers outweigh smaller ones in terms of participation intensity but not participation frequency. Internationally, stakeholders from countries with a private financial accounting standard-setting system participate more frequently and intensively than others. In addition, country-level economic wealth and sustainability performance are positively associated with more participating stakeholders.

Practical implications

This study is of interest for organizations and stakeholders involved in or affected by standard-setting in the field of sustainability reporting. The finding of limited participation by investors and from developing countries suggests the ISSB take actions to enhance the voice of those stakeholders.

Social implications

The imbalances in stakeholder participation that were found pose potential threats to an important aspect of the input legitimacy of the ISSB’s standard-setting process.

Originality/value

To the best of the authors’ knowledge, this paper is the first to explore stakeholder participation by means of CLs with the ISSB in terms of frequency and intensity.
Insectivorous bats alter their flight and feeding behaviour at ground‐mounted solar farms
Authors: Barré Kévin , Baudouin Alice , Froidevaux Jérémy S. P. , Chartendrault Vivien , Kerbiriou Christian
Published: December 2023

Efforts to mitigate the climate crisis result in a green‐green dilemma: the development of renewable energy technology is required worldwide to reduce greenhouse gas emissions but can have negative impacts on biodiversity. Impacts are being documented for wind farms, but effects of solar farms (photovoltaic power stations) on habitat use of vertebrates remain extremely poorly known.

Using insectivorous bats as a biological model for high trophic levels, we tested whether the presence of ground‐mounted solar farms affected flight and feeding behaviour. We assessed behaviour using three‐dimensional flight path reconstruction systems from echolocation calls, via standardised paired sampling of 16 control and 16 solar farm (treatment) sites. We quantified bat flight and feeding behaviour as flight speed, sinuosity of flight trajectories, and the probability of emission of feeding buzzes (acoustic signatures of prey capture attempts), and demonstrated that feeding was characterised by slow, sinuous flight with feeding buzzes.

We recorded 15,273 three‐dimensional bat positions, resulting in 1317 flight trajectories. We found strong behavioural responses to ground‐mounted solar farms in two of three bat guilds and five of seven taxa. Specifically, bats shifted their flight towards faster (+10 to +44%) and straighter trajectories (+33%) with lower probability of prey capture attempts (−18 to −39%) at solar farms.

Since these changes in flight features are explicit indicators of a decrease in bat feeding behaviour, the implementation of ground‐mounted solar farms is likely to result in reduced feeding habitat quality for bats.

Synthesis and applications: The negative effects of solar farms on bat flight and feeding behaviour should be considered when solar energy projects are planned. Research is needed to understand the mechanisms underlying the effects; for example, shading underneath solar panels may reduce plant biomass and therefore insect prey availability. Until exact mechanisms are identified, efforts should be made, first to avoid building solar farms on sites with great feeding potential for bats, and second to offset residual effects by improving the surrounding land and/or solar farms to provide better foraging opportunities. In this way, populations of bats can be supported alongside the generation of renewable energy.
The Economic Consequences of Mr Trump and Mr Biden
Authors: Garnaut Ross
Published: December 2023

Max Corden and Ross Garnaut published ‘The Economic Consequences of Mr Trump’ in this journal in 2018. This paper examines what has transpired in the US economy against that article. It notes continuity in budget and trade policy from the Trump Presidency to the Biden Presidency. The continuity in macro‐fiscal and trade policies is accompanied by a significant departure in the focus of fiscal expansion: Mr Biden's strong support for decarbonisation. The article applies Max Corden's approach to international economics to the question: should Australia emulate Mr Biden's combination of budget, protection and decarbonisation policies?
EU Outlook for Biomass Flows and Bio‐based Products
Authors: van Leeuwen Myrna , Gonzalez‐Martinez Ana , Sturm Viktoriya
Published: December 2023

The Bioeconomy Strategy Action Plan calls for sustainable extraction, processing, and use of biological resources in Europe as a pathway to achieve environmental, social and economic goals. However, the transition towards sustainable food systems within and across countries is diverse due to the existing heterogeneous land patterns and agricultural production structures, the variety of potential industries competing for specific biomass feedstocks, and the national policy frameworks in place. Therefore, it is key for policymakers to understand how biomass is supplied, and how it flows through the economy and is used for alternative purposes. This calls for tools that can monitor and quantitatively analyse these aspects. BioMAT has projected the annual growth rate of the EU bio‐based chemical production from 2018 to 2030 to be four times higher than its fossil‐based counterpart. The associated net‐availability of industrial sugars in 2030 is quite balanced, but excess demands for starch and plant oils will increase to fulfil requirements of a growing bio‐based chemical sector. As a vast amount of biological feedstock for material use originates from non‐EU regions (e.g. palm oil), sustainable sourcing and a better use of biological residues should be emphasised. Scenario analyses are helpful to consider consequences of assessing different technical pathways or policies.
Urinary incontinence associates with poor work ability in middle‐aged women: A Northern Finland Birth cohort 1966 study
Authors: Salo Heini , Mäkelä‐Kaikkonen Johanna , Sova Henri , Piltonen Terhi , Laru Johanna , Ala‐Mursula Leena , Rossi Henna‐Riikka
Published: December 2023

Introduction

Urinary incontinence is a common ailment in women and is likely to affect their work ability. We investigated the associations between the different subtypes of urinary incontinence and several dimensions of perceived work ability in middle‐aged general population.

Material and methods

Cross‐sectional survey at age 46 among participants of the Northern Finland Birth Cohort 1966 study (n = 3706, response rate 72%). Urinary incontinence symptoms and several items of Work Ability Index were collected by postal questionnaire. Work ability was dichotomized as good or poor work ability in general, in relation to physical job demands, to diseases and own 2‐year prospect of work ability. The associations between urinary incontinence and work ability measures were assessed using logistic regression models, with further adjustments for biological, behavioral and work‐related factors as well as general health.

Results

The odds ratio (OR), from lowest to highest, for poor work ability were 1.4‐fold among women with stress urinary incontinence (OR 1.37, 95% confidence interval [CI] 1.09–1.72), 2.5‐fold with mixed urinary incontinence (OR 2.51, 95% CI 1.68–3.74) and 3.3‐fold with urgency urinary incontinence (OR 3.34, 95% CI 1.95–5.70). We note that our results reflect work ability in a Nordic society.

Conclusions

Especially urgency and mixed types of urinary incontinence are associated with poor work ability among middle‐aged women.
Bifidobacterium breve Bif195 ameliorates aspirin‐induced gastric mucosal damage: A randomised, double blind, placebo‐controlled crossover trial
Authors: Løn Nina , Engel Sara , Damholt Anders , Mortensen Brynjulf , Haaber Anne B. , Wellejus Anja , Knop Filip K.
Published: December 2023

Background

Gastric and duodenal ulcerations are common during multiple‐dosing aspirin treatment, such as for prevention of cardiovascular disease. On capsule endoscopy, oral administration of the bacterial strain Bifidobacterium breve Bif195 (DSM 33360) reduced the risk of aspirin‐induced small intestinal damage, without affecting cyclo‐oxygenase‐2 (COX‐2) inhibition.

Aim

To evaluate endoscopically the effect of Bif195 on aspirin‐induced stomach and duodenal mucosal damage

Methods

Twenty‐five healthy volunteers underwent two intervention periods in a randomised, double‐blind, placebo‐controlled crossover design including four gastroduodenoscopies and 6 weeks washout. Each intervention was a 4‐week oral co‐treatment of aspirin 300 mg daily and Bif195 (≥1011 colony‐forming units daily) or placebo. Primary endpoint was change in Lanza score ‐ ranging from 0 (normal mucosa) to 4 (>10 erosions or ulcer).

Results

All 25 participants (56% females); age 27.3 (±4.8) years; BMI 23.2 (±3.4) kg/m2, completed the trial exhibiting significant increases in Lanza scores during placebo treatment as compared to baseline. Bif195 reduced gastric Lanza score with an odds ratio of 7.2 (95% confidence interval 1.72–30.08, p = 0.009) compared to placebo with no related adverse events. There were no significant changes in Lanza scores in the duodenum.

Conclusions

Bif195 reduces aspirin‐induced gastric mucosal damage and may serve as a safe supplement during multiple‐dosing aspirin treatment.
Tranexamic acid for percutaneous nephrolithotomy: an abridged Cochrane review
Authors: Cleveland Brent , Norling Brett , Wang Hill , Gandhi Vardhil , Price Carrie L. , Borofsky Michael , Pais Vernon , Dahm Philipp
Published: December 2023

Objective

To assess the effects of tranexamic acid (TXA) in individuals with kidney stones undergoing percutaneous nephrolithotomy (PCNL).

Patients and Methods

We performed a literature search of Cochrane Library, PubMed (including MEDLINE), Embase, Scopus, Global Index Medicus, trials registries, grey literature, and conference proceedings. We included randomised controlled trials (RCTs) that compared treatment with PCNL with administration of TXA to placebo (or no TXA) for patients aged ≥18 years. Two review authors independently classified studies and abstracted data. Primary outcomes were blood transfusion, stone‐free rate (SFR), thromboembolic events (TEE). We rated the certainty of evidence (CoE) according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach using a minimally contextualised approach with pre‐defined thresholds for minimally clinically important differences (MCID).

Results

We included 10 RCTs assessing the effect of systemic TXA in PCNL vs placebo (or no TXA). Eight studies were published as full text. Based on an adjusted baseline risk of blood transfusion of 5.7%, systemic TXA may reduce blood transfusions (risk ratio [RR] 0.45, 95% confidence interval [CI] 0.27–0.76). Based on an adjusted baseline SFR of 75.7%, systemic TXA may increase SFR (RR 1.11, 95% CI 0.98–1.27). There is probably no difference in TEEs (risk difference 0.001, 95% CI −0.01 to 0.01). Systemic TXA may increase adverse events (AEs) (RR 5.22, 95% CI 0.52–52.72). Systemic TXA may have little to no effect on secondary interventions (RR 1.15, 95% CI 0.84–1.57). The CoE for most outcomes was assessed as low or very low.

Conclusions

Based on a body of evidence of 10 RCTs, we found that systemic TXA in PCNL may reduce blood transfusions, major surgical complications, and hospital length of stay, as well as improve the SFR; however, it may increase AEs. These findings should inform urologists and their patients in making informed decisions about the use of TXA in the setting of PCNL.
How far can I extrapolate my species distribution model? Exploring shape, a novel method
Authors: Velazco Santiago José Elías , Rose Miranda Brooke , De Marco Paulo , Regan Helen M. , Franklin Janet
Published: December 2023

Species distribution and ecological niche models (hereafter SDMs) are popular tools with broad applications in ecology, biodiversity conservation, and environmental science. Many SDM applications require projecting models in environmental conditions non‐analog to those used for model training (extrapolation), giving predictions that may be statistically unsupported and biologically meaningless. We introduce a novel method, Shape, a model‐agnostic approach that calculates the extrapolation degree for a given projection data point by its multivariate distance to the nearest training data point. Such distances are relativized by a factor that reflects the dispersion of the training data in environmental space. Distinct from other approaches, Shape incorporates an adjustable threshold to control the binary discrimination between acceptable and unacceptable extrapolation degrees. We compared Shape's performance to five extrapolation metrics based on their ability to detect analog environmental conditions in environmental space and improve SDMs suitability predictions. To do so, we used 760 virtual species to define different modeling conditions determined by species niche tolerance, distribution equilibrium condition, sample size, and algorithm. All algorithms had trouble predicting species niches. However, we found a substantial improvement in model predictions when model projections were truncated independently of extrapolation metrics. Shape's performance was dependent on extrapolation threshold used to truncate models. Because of this versatility, our approach showed similar or better performance than the previous approaches and could better deal with all modeling conditions and algorithms. Our extrapolation metric is simple to interpret, captures the complex shapes of the data in environmental space, and can use any extrapolation threshold to define whether model predictions are retained based on the extrapolation degrees. These properties make this approach more broadly applicable than existing methods for creating and applying SDMs. We hope this method and accompanying tools support modelers to explore, detect, and reduce extrapolation errors to achieve more reliable models.

Keywords: environmental novelty, extrapolation, Mahalanobis distance, model prediction, non‐analog environmental data, transferability
Access to a regular primary care physician among young people with early psychosis in Ontario, Canada
Authors: Rodrigues Rebecca , Reid Jennifer N. S. , Wiener Joshua C. , Archie Suzanne , Booth Richard G. , Cheng Chiachen , MacDougall Arlene G. , Palaniyappan Lena , Ryan Bridget L. , Voineskos Aristotle , Kurdyak Paul , Jan Saadia Hameed , Anderson Kelly K. ,   the project co‐investigators
Published: December 2023

Aim

Access to a primary care physician in early psychosis facilitates help‐seeking and engagement with psychiatric treatment. We examined access to a regular primary care physician in people with early psychosis, compared to the general population, and explored factors associated with access.

Methods

Using linked health administrative data from Ontario (Canada), we identified people aged 14–35 years with a first diagnosis of nonaffective psychotic disorder (n = 39 449; 2005–2015). We matched cases to four randomly selected general population controls based on age, sex, neighbourhood, and index date (n = 157 796). We used modified Poisson regression to estimate prevalence ratios (PR) for access to a regular primary care physician in the year prior to first diagnosis of psychotic disorder, and the sociodemographic and clinical factors associated with access.

Results

A larger proportion of people with early psychosis had a regular primary care physician, relative to the general population (89% vs. 68%; PR = 1.30, 95%CI = 1.30–1.31). However, this was accounted for by a higher prevalence of comorbidities among people with psychosis, and this association was no longer present after adjustment (PR = 0.97, 95%CI = 0.97, 0.98). People with early psychosis who were older, male, refugees and those residing in lower income or high residential instability neighbourhoods were less likely to have a regular primary care physician.

Conclusion

Approximately one in ten young people with early psychosis in Ontario lack access to a regular primary care physician. Strategies to improve primary care physician access are needed for management of physical comorbidities and to ensure continuity of care.
The COVID‐19 pandemic and neurology: A survey on previous and continued restrictions for clinical practice, curricular training, and health economics
Authors: Rakusa Martin , Moro Elena , Akhvlediani Tamar , Bereczki Daniel , Bodini Benedetta , Cavallieri Francesco , Fanciulli Alessandra , Filipović Saša R. , Guekht Alla , Helbok Raimund , Hochmeister Sonja , Martinelli Boneschi Filippo , Özturk Serefnur , Priori Alberto , Romoli Michele , Willekens Barbara , Zedde Marialuisa , Sellner Johann ,   the NeuroCOVID‐19 Task Force of the European Academy of Neurology
Published: December 2023

Background and Purpose

The COVID‐19 pandemic has significantly impacted health systems worldwide. Here, we assessed the pandemic's impact on clinical service, curricular training, and financial burden from a neurological viewpoint during the enforced lockdown periods and the assumed recovery by 2023.

Methods

An online 18‐item survey was conducted by the European Academy of Neurology (EAN) NeuroCOVID‐19 Task Force among the EAN community. The survey was online between February and March 2023. Questions related to general, demographic, clinical, work, education, and economic aspects.

Results

We collected 430 responses from 79 countries. Most health care professionals were aged 35–44 years, with >15 years of work experience. The key findings of their observations were as follows. (i) Clinical services were cut back in all neurological subspecialties during the most restrictive COVID‐19 lockdown period. The most affected neurological subspecialties were services for patients with dementia, and neuromuscular and movement disorders. The levels of reduction and the pace of recovery were distinct for acute emergencies and in‐ and outpatient care. Recovery was slow for sleep medicine, autonomic nervous system disorders, neurorehabilitation, and dementia care. (ii) Student and residency rotations and grand rounds were reorganized, and congresses were converted into a virtual format. Conferences are partly maintained in a hybrid format. (iii) Affordability of neurological care and medication shortage are emerging issues.

Conclusions

Recovery of neurological services up to spring 2023 has been incomplete following substantial disruption of neurological care, medical education, and health economics in the wake of the COVID‐19 pandemic. The continued limitations for the delivery of neurological care threaten brain health and call for action on a global scale.
Morphology and behavior of ergatandromorph in Camponotus yamaokai Terayama & Satoh, 1990 (Hymenoptera: Formicidae)
Authors: Chiyoda Kazuma , Yoshimura Hiro , Inoue Kanata , Yamasaki Kazuhisa , Satoh Toshiyuki , Koyama Satoshi
Published: December 2023

Ergatandromorphs are examples of genetic chimeras found in ants, in which they exhibit features of both minor workers and males. In this study, we report a lateral ergatandromorph of Camponotus yamaokai Terayama & Satoh, 1990. The right side of this specimen was characterized as a male and the left side as a minor worker, although some body parts did not show a clear division. The specimen had partially atrophied genitalia on the right side of the metasoma while the genital structures on the left side were absent. The individual engaged in frequent self‐grooming and received trophallaxis and allogrooming from the nestmates. This is the first report of the lateral ergatandromorph in the genus Camponotus, which has few documented cases of gynandromorphism.
Deficiency of Pdcd10 causes urothelium hypertrophy and vesicle trafficking defects in ureter
Authors: Wang Yixuan , Ma Baotao , Jian Youli , Wu Shi‐Ting , Wong Alex , Wong Justin , Bonder Edward M. , Zheng Xiangjian
Published: December 2023

The scaffolding protein programmed cell death protein 10 (Pdcd10) has been demonstrated to play a critical role in renal epithelial cell homeostasis and function by maintaining appropriate water reabsorption in collecting ducts. Both ureter and kidney collecting duct systems are derived from the ureter bud during development. Here, we report that cadherin‐16 (Cdh16)‐cre drives gene recombination with high specificity in the ureter, but not the bladder, urothelium. The consequences ofPdcd10deletion on the stratified ureter urothelium were investigated using an integrated approach including messenger RNA (mRNA) expression analysis, immunocytochemistry, and high‐resolution confocal and electron microscopy. Loss ofPdcd10in the ureter urothelium resulted in increased expression of uroplakins (Upks) and keratins (Krts), as well as hypertrophy of the ureter urothelium with an associated increase in the number of proliferation marker protein Ki‐67 (Ki67)‐expressing cells specifically within the basal urothelium layer. Ultrastructural analysis documented significant modification of the intracellular membrane system, including intracellular vesicle genesis and transport along the basal‐ to umbrella‐cell‐layer axis. Additionally,Pdcd10loss resulted in swelling of Golgi compartments, disruption of mitochondrial cristae structure, and increased lysosomal fusion. Lack ofPdcd10also resulted in decreased fusiform vesicle formation in umbrella cells, increased secretion of exosome vesicles, and alteration in microvillar structure on apical membranes. Our findings indicate thatPdcd10expression and its influence on homeostasis is associated with modulation of endomembrane trafficking and organelle biogenesis in the ureter urothelium.
New Insights into the Formation and Properties of Wellbore Skin: Why We Have to Rethink the Concept
Authors: Houben Georg J. , Lamparter Axel , Ufer Kristian , Damian Christin , Boz Daniel
Published: December 2023

The deposition of fine‐grained material of low permeability on the borehole wall during drilling (wellbore skin) is a common problem affecting the operation and efficiency of water wells. Here, we present new data and novel insights from four excavated dewatering wells from a lignite surface mine. All wells have the same age, are of similar construction, and were sampled at two different depths each. The thickness of the skin layer increases with depth. Its composition and permeability is strongly influenced by the surrounding aquifer material. Nonuniform sediments of low permeability result in less permeable wellbore skin deposits. The presence of discontinuities in the skin layer may be a determining feature for the resulting flow to wells, especially with skin layers of low permeability. The presence of naturally occurring swelling clay (smectite) provides the skin layer with a significant self‐sealing capacity.
How do Twitter users feel about telehealth? A mixed‐methods analysis of experiences, perceptions and expectations
Authors: Sazon Hannah , Catapan Soraia de Camargo , Rahimi Afshin , Canfell Oliver J. , Kelly Jaimon
Published: December 2023

Background

Telehealth use has increased considerably in the last years and evidence suggests an overall positive sentiment towards telehealth. Twitter has a wide userbase and can enrich our understanding of telehealth use by users expressing their personal opinions in an unprompted way. This study aimed to explore Twitter users' experiences, perceptions and expectations about telehealth over the last 5 years.

Methods

Mixed‐methods study with sequential complementary quantitative and qualitative phases was used for analysis stages comprising (1) a quantitative semiautomated analysis and (2) a qualitative research‐led thematic analysis. A machine learning model was used to establish the data set with relevant English language tweets from 1 September 2017 to 1 September 2022 relating to telehealth using predefined search words. Results were integrated at the end.

Results

From the initial 237,671 downloaded tweets, 6469 had a relevancy score above 0.8 and were input into Leximancer and 595 were manually analysed. Experiences, perceptions and expectations were categorised into three domains: experience with telehealth consultation, telehealth changes over time and the purpose of the appointment. The most tweeted experience was expectations for telehealth consultation in comparison to in‐person consultations. Users mostly mentioned the hope that waiting times for the consultations to start to be less than in‐person, more telehealth appointments to be available and telehealth to be cheaper. Perceptions around the use of telehealth in relation to healthcare delivery changes brought about by the COVID‐19 pandemic were also expressed. General practitioners were mentioned six times more than other healthcare professionals.

Conclusion/Implications

This study found that Twitter users expect telehealth services to be better, more affordable and more available than in‐person consultations. Users acknowledged the convenience of not having to travel for appointments and the challenges to adapt to telehealth.

Patient or Public Contribution

An open data set with 237,671 tweets expressing users' opinions in an unprompted way was used as a source for telehealth service users, caregivers and members of the public experiences, perceptions and expectations of telehealth.
HIV pre‐exposure prophylaxis services, provision, and delivery in the European treatment network of HIV, hepatitis and global emerging infectious diseases (NEAT ID)
Authors: Liegeon Geoffroy , Duffy Annie , Brooks Caroline , Honour Hannah , Pozniak Anton , Molina Jean Michel ,   the NEAT ID PrEP survey group
Published: December 2023

Objectives

We conducted a survey to evaluate HIV pre‐exposure prophylaxis (PrEP) practices in a European clinical research network on HIV, hepatitis, and global infectious diseases (NEAT ID).

Methods

An online survey comprising 22 questions was sent via a secure electronic tool to the investigating physician of each of the 342 NEAT ID study centres across 15 European countries in November 2020.

Results

In total, 50 sites from 12 countries responded (15% response rate). Most sites were in Western Europe, two were in Poland, and one was in Hungary. Of the responding sites, 45 provided PrEP services for a total of 27 416 PrEP users, with 1361 new PrEP initiators each month. These centres supplied PrEP for men who have sex with men (100%), people who inject drugs (84%), sex workers (84%), women (62%), and transgender women (31%). PrEP persistence after 1 year was >90%, 75%–90%, and 40%–75% in 17, 24, and 4 centres, respectively. In total, 32/45 (71%) centres reported strong community‐based organization commitment at their site, and 15/45 (33%) centres developed task‐shifting processes to deliver PrEP through nurses (11/15), pharmacists (5/15), and key‐population peers (2/15). The biggest barriers to implementation of PrEP were low awareness of and knowledge about PrEP (47%), unwillingness to disclose sexual identity or at‐risk behaviour (36%), and lack of administrative support (29%). Of the 45 centres, 32 (71%) have already been involved in PrEP research and 43 (96%) were interested in participating in such studies.

Conclusions

The few NEAT ID centres that responded to the survey showed disparities in PrEP deployment and practices despite a common interest in participating in research in this field.
The link between learner engagement and self‐regulation. A multiple case study
Authors: Mystkowska‐Wiertelak Anna , Bielak Jakub
Published: December 2023

The topic of language learners’ engagement, which has enjoyed immense popularity in recent years, emerged more than 20 years ago from the explorations of individual and social variables in task performance. In the domain of second/foreign language acquisition, what has attracted much attention is the relationship between engagement and other approximate concepts, such as motivation, interest, or investment, but little is known about the connection between self‐regulation and engagement. Hence, the present study was undertaken to explore the connection between L2 learners’ engagement and their self‐regulated strategy use. Semi‐structured interviews were conducted with two students, labeled by their teachers as highly engaged, and another two, described as disengaged. The results suggest that the two frameworks are interconnected but not fully analogous, with the main difference lying in the conceptualization of the role motivation
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Full‐body skin examination in screening for cutaneous malignancy: a focus on concealed sites and the practices of Australian dermatologists
Authors: Pham James P. , Allen Nicholas , Star Phoebe , Cust Anne E. , Stewart Cameron , Guitera Pascale , Marghoob Ashfaq A. , Smith Annika
Published: December 2023

Background

Full‐body skin examination (FSE) is a vital practice in the diagnosis of cutaneous malignancy. Precisely how FSE should be conducted with respect to concealed site inclusion remains poorly elucidated.

Objective

To establish the approach of Australian dermatologists to concealed site examination (CSE).

Methods

A cross‐sectional study was performed consisting of an online self‐administered 11‐question survey delivered to fellows of the Australasian College of Dermatologists.

Results

There were 237 respondents. Anogenitalia was the least often examined concealed site (4.6%), and 59.9, 32.9, and 14.3% reported always examining the scalp, breasts, and oral mucosa, respectively. Patient concern was the most frequently cited factor prompting examination, while many cited low incidence of pathology and limited chaperone availability as the main barriers to routine examination of these sites.

Conclusion

Most Australian dermatologists do not routinely examine breasts, oral mucosal, or anogenital sites as part of an FSE. Emphasis should be made on identifying individual patient risk factors and education regarding self‐examination of sensitive sites. A consensus approach to the conduct of the FSE, including concealed sites, is needed to better delineate clinician responsibilities and address medicolegal implications.
Comparative analysis of volatile components of fresh and dried Tuber indicum truffles with different extraction methods
Authors: Ma Yanmei , Feng Na , Zhou Shuai , Han Wei , Zhang Jingsong , Xiong Haikuan
Published: December 2023

Tuber indicum Cook&Massee (T. indicum) is mainly distributed in China, and it is also the truffle species with the largest yield China. Investigation and utilisation of its volatile components is still limited. By using headspace solid‐phase microextraction (HS‐SPME) and gas chromatography–mass spectrometry (GC–MS), the volatile components of fresh and dried T. indicum were compared in this study. It was found that after hot‐air drying of T. indicum, 73 components were retained in the truffles, and the remaining components changed during the drying process. The relative contents of alcohols and aldehydes in the dried truffles decreased by approximately 40% and 83%, respectively, while the relative contents of acids and esters increased by approximately 14 times and 5.5 times respectively. The drying process severely disrupts the flavour of the truffles. In advance, three extraction methods (steam distillation, Soxhlet extraction and supercritical CO2 fluid extraction [CO2‐SFE]) were performed on dried and fresh T. indicum, and their volatile components were compared. The results indicated that the alkanes extracted from fresh and dried truffles by steam distillation and Soxhlet extraction accounted for 30%–48%, while a richer variety of compounds were extracted from the two truffles by CO2‐SFE, with acids, esters and alcohols together amounting to approximately 70% in quantity, and they exceeded 95% in relative content. A richer variety of volatile compounds was extracted, and more fatty acids which yielded greasy, creamy, sweet and mushroomy aromas were enriched by CO2‐SFE compared to steam distillation and Soxhlet extraction. Therefore, CO2‐SFE extraction is a suitable method for extracting volatile components from T. indicum.
Development of microencapsulated dried Bacillus sp. 63‐11 with enhanced shelf stability and bioactivity for use as a food supplement
Authors: Khullar Gauri , Karami Zohreh , Prakitchaiwattana Cheunjit
Published: December 2023

The impact of drying processes and encapsulation techniques of Bacillus sp. 63‐11 was explored in relation to the stability and bioactive properties of microencapsulated particles. Modified starch (MS) or maltodextrin (MD) were evaluated using freeze drying (FD) or hot‐air drying (HD) protocols. The HD‐dried cells showed significantly improved viability and appearance when compared to FD. HD‐MD cells exhibited 2 log CFU higher viability, lower contamination, and deeper pigmentation than HD‐MS, and superior gastrointestinal tolerance as compared to fresh cells during storage, enhanced it's probiotic potential. HD‐MD cells also exhibited dose‐dependent antibiotic susceptibility, strong antagonistic activities and consistently high antioxidant activity, i.e., Trolox equivalent antioxidant capacity at 0.4 g mL−1. Additional shelf‐life testing in five food models for 90 days revealed remarkable bio‐preservative potential, particularly in high‐fat models. The study highlights the impact on probiotic potential and bioactivity of hot air‐dried encapsulated Bacillus species.
Impact of protein blend formulation and extrusion conditions on the physical properties of texturised pea protein‐extended beef burgers
Authors: Chan Elyssa , Sinaki Nasibe Y. , Rodas‐González Argenis , Tulbek Mehmet , Koksel Filiz
Published: December 2023

This study aimed to assess the physical properties of pea‐based texturised vegetable proteins (TVPs) and TVP function as a meat extender (20%–40% w/w) in beef burgers. TVPs were produced with varying protein blend formulas (PBFs) (70%, 76%, 82% protein on a dry basis), extrusion screw speeds (350–450 r.p.m.) and feed moisture contents (FMCs) (38% and 42%, db). Increasing PBF raised TVP hydration time and integrity index, while FMC and screw speed had no discernable trend on these properties. A select group of TVPs were applied as extenders in beef burgers which were tested for their cooking properties and textural quality. Higher FMC lowered total cooking loss (TCL) for some burgers but overall did not impact burger cooking properties or texture. Increasing the extension level reduced TCL and change in burger diameter (CBD). TVPs produced at the lowest PBF and higher FMC studied had the greatest potential in meat extender applications, as they decreased TCL and CBD while maintaining comparable texture to burgers without TVP addition. These lower protein TVPs with enhanced cooking quality can be economically advantageous for the vegetarian and flexitarian applications of plant‐based extenders.