bluuebunny/crossref_metadata_2025 huggingface dataset:
White privilege and professionalization: a decolonial and critical feminist perspective on professional nursing
Authors: Stake-Doucet Natalie
Published: December 2023

This article offers a critical perspective linking invisibility with the political foundations of the dominant, Eurocentric model of modern nursing. Using critical feminist and decolonial feminist frameworks, this paper begins by analyzing gendered, reproductive labor in the centuries leading up to the industrial revolution in Britain and Europe and how the current dominant model of nursing was developed. The second part of the paper suggests a critical link between white supremacy, colonial violence and the professionalization of nursing work. Finally this paper calls on nursing scholarship to move beyond the narrow definition of nursing within the professional framework to include people who have done and continue to do the work of nursing despite being denied the title because of segregation and colonial violence.
Análise da prevalência e características do burnout em profissionais da saúde que atuaram em hospitais de referência para COVID-19 no ES
Authors: Acerbi Murillo José de Abreu , Modesto Artur Pinho Reis , Soares Gabriel Silveira Schwartz , Borges Stênio de Oliveira Ramaldes Fafá , Martins Liliani Travezani , Marques Marcelita França , Lenz Dominik , Corrêa Mônica Cola Cariello Brotas , Rua Sergio Emilio , Endringer Denise Coutinho
Published: December 2023

Introdução: A doença viral denominada COVID-19, causada pelo SARS-CoV-2, iniciou seu curso infeccioso pela China em dezembro de 2019 e levou a OMS a declarar estado de pandemia global em 30 de janeiro de 2020, afetando drasticamente a saúde física e mental de uma parcela considerável da população mundial. Paralelo a esse quadro, a síndrome de burnout tem uma alta incidência entre os profissionais da área da saúde, principalmente frente a condições adversas de trabalho, dentre as quais podemos destacar uma recém-descoberta pandemia viral com tamanho poder de infectividade como o SARS-CoV-2. Objetivo: Analisar as características e prevalência do burnout presente em profissionais em área de tratamento referência COVID-19, e propor ideias de enfrentamento. Método: A pesquisa é composta de duas etapas: 1- avaliação inicial, e 2- avaliação final. Um questionário sistematizado, com 40 questões, foi aplicado aos profissionais da área. Resultado: Dentre os 96 entrevistados na avaliação inicial, segundo os preditores indicados pelo Grupo de Estudo e Pesquisa sobre Stress e Síndrome de Burnout, apenas 32 médicos pontuaram dentro dos níveis que sugerem burnout (Baixo, Médio e Alto), sendo que o nível “Médio” das três dimensões analisadas (Exaustão Emocional, Despersonalização, Realização Pessoal) foi o mais prevalente. Conclusão: Diante desse contexto, a caracterização da síndrome de burnout nos profissionais da saúde é de fundamental importância para o delineamento de estratégias de promoção de saúde mental e qualidade de vida destes profissionais, submetidos à alta carga de trabalho e a diversos sentimentos negativos observados.
Multi-Disciplinary and Multi-Objective Optimization Method Based on Machine Learning
Authors: Dai Jiahua , Liu Peiqing , Li Ling , Qu Qiulin , Niu Tongzhi
Published: December 2023

The optimization of aircraft is a typical multidisciplinary and multi-objective problem. To solve this problem, the difficulty lies not only in the high cost of discipline performance evaluation but also in the complex coupling relationship between different disciplines. To improve the optimization efficiency, a new optimization method is proposed, including two new algorithms: conditional generative adversarial nets with vector similarity (VS-CGAN) and distributed single-step deep reinforcement learning with transfer learning (TL-DSDRL). For low-cost disciplines, VS-CGAN learns the relationship between variables and objectives through presampling to compress the variable domains. The cosine function is used to evaluate the similarity between the random noise and generated variables to avoid mode collapse. For high-cost disciplines, TL-DSDRL improves optimization efficiency through pretraining. The newly designed reward function and multi-agent cooperation mechanism enhance the multi-objective search ability of reinforcement learning.
Duct Effects on Acoustic Source Radiation
Authors: Baddour Benjamin , Joseph Phillip , McAlpine Alan , Leung Ronnie
Published: December 2023

This paper presents a detailed numerical investigation of the effects of a semi-infinite hard-walled duct on the radiation due to point dipole sources rotating around the duct axis. In particular, this study is concerned with the effect of source position relative to the duct open end and its comparison with radiation in a free field. This study was motivated by the increasing tendency of ducted propellers and fans to be located close to the open end, relative to the acoustic wavelength. In this study, the conditions under which duct effects on source radiation may be neglected are established.
IMMUNE LANDSCAPE FEATURES OF TONGUE CANCER IN YOUNG ADULTS
Authors:   Cancer Research Institute, Tomsk National Research Medical Center RAS, Prostakishina E.A. , Patysheva M.R. , Kolegova E.S. , Khozyainova A.A. , Menyailo M.E. , Larionova I.V. , Fedorova I.K. , Kulbakin D.E. , Choinzonov E.L. , Denisov E.V.
Published: December 2023

In our work, we investigated the immune landscape features of patients younger than 45 years of age with tongue cancer using spatial transcriptomics technology at the single-cell level. The study revealed that tongue cancer in young adults is characterized by immunosuppression.
INVESTIGATION OF CHANGES IN THE EXPRESSION OF MRNA SUBUNITS OF HETEROMERIC NICOTINIC ACETYLCHOLINE RECEPTORS IN MACROPHAGES UNDER DIFFERENT TYPES OF DIFFERENTIATION AND EXPOSURE TO VARIOUS LIGANDS
Authors:   Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Kholoshenko I.V. ,   Mendeleev University of of Chemical Technology of Russia, Moscow, Gondarenko E.A. , Shelukhina I.V.
Published: December 2023

The widespread prevalence and high mortality from sepsis indicates that the mechanisms of inflammatory processes are not fully understood and, as a result, the developed methods for treating sepsis are not effective enough. Cholinergic anti-inflammatory reflex makes a significant contribution to the suppression of sepsis, this process is also accompanied by changes in the level of expression of surface protein markers of macrophages involved in inflammation and immunosuppression in sepsis, which opens up new possibilities for the creation of treatment. In this work, we have identified the role of 9 nAChR subunit in the production of anti-inflammatory cytokines.
COMBINED TREATMENT OF PATIENTS WITH STAGE IV GASTRIC CANCER BASED ON ASSESSMENT OF CHEMOSENSITIVITY AND ABC TRANSPORTER GENE EXPRESSION LEVELS
Authors:   Cancer Research Institute, Тomsk National Research Medical Center RAS, Tsydenova I.A. ,   Tomsk State University,   Siberian State Medical University, Tomsk, Markovich V.A. , Kravtsova E.A. , Dolgasheva D.S. , Tsyganov M.M. , Litviakov N.V.
Published: December 2023

Metastatic tumours are known to have heterogeneity between primary and metastatic sites. This type of heterogeneity is the cause of low efficacy of therapy. In this regard, comparative analysis of ABC-transporter gene expression and chemosensitivity genes will make it possible to determine the resistance and sensitivity of tumours to therapy and provide a basis for a personalised treatment approach.
HETEROLOGOUS EXPRESSION OF PYROCYSTIS LUNULA LUCIFERASE GENE IN PLANT CELLS
Authors:   Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Shakhova E.S. , Myshkina N.M. , Zagitova R.I. , Kotlobay A.A. , Morozov V.V. , Balakireva A.V. , Yampol’skij I.V. , Osipova Z.M.
Published: December 2023

Bioluminescence of dinoflagellates is a result of oxidation of the luciferin, which belongs to the class of tetrapyrroles and is possibly a product of chlorophyll a catabolism. We have demonstrated the functionality of the dinoflagellate luciferase gene from P. lunula in the transient and stable transformation of N. tabacum BY-2 cell culture. The results will be used further for the investigation of the luciferin biosynthetic pathway
CHARACTERIZATION OF EXOSOMAL PROTEINS DERIVED FROM DIFFERENT BREAST CELL LINES AND SEARCH FOR CANDIDATE PROTEINS FOR LIQUID BIOPSY
Authors:   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Shefer A.A. , Yanshole L.V. , Grigorieva A.E. , Tamkovich S.N. ,   Novosibirsk State University,   International Tomography Center SB RAS, Novosibirsk
Published: December 2023

Exosomes are extracellular vesicles secreted by the cells of the organism and are present in various biological fluids. They provide signal transduction between cells both in normal biological processes and in various pathological conditions including breast cancer. In this study, we isolated and characterized exosomes secreted by different breast cancer cell lines and identified proteins in their composition.
CREATION OF HUMAN CELL LINES WITH A REDUCED CONTENT OF KU ANTIGEN SUBUNITS USING THE CRISPR/CAS9 SYSTEM
Authors:   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Yamskikh A.A. , Ilina E.S. , Dyrkheeva N.S. , Medvedev S.P. , Malakhova A.A. , Zakian S.M. , Khodyreva S.N. , Lavrik O.I. ,   Institute of Cytology and Genetic SB RAS, Novosibirsk
Published: December 2023

In this work, using the CRISPR/Cas9 system, we obtained clones of HEK293A and HEK293FT cell lines with a reduced content of Ku70 or Ku80 proteins. The decrease in the target proteins amount was confirmed by Western blot analysis and affinity modification with chemically active DNA.
Humilisin E: Strategy for Synthesis and Access to the Functionalized Bicyclic Core
Authors: Verma Prachi , Pallerla Rajanish , Rolig Aino , Pihko Petri
Published: December 2023

Humilisin E is a diterpenoid possessing a rare epoxidized cyclononene trans-fused with the bicycle[3.2.0]heptane core. Here, we identify a potential biosynthetic precursor, the (P) atropisomer of the corresponding diene, and report two different strategies for the stereocontrolled synthesis of the appropriately functionalized bicyclic core of humilisin E. The first route involves a Stork epoxynitrile cyclization via the corresponding Mg alkoxide, and the second, more stereoselective approach utilizes the Wolff rearrangement as the key step.
Stimuli-Sensitive Polymer Prodrug Nanocarriers by Reversible-Deactivation Radical Polymerization
Authors: Guerassimoff Léa , Ferrere Marianne , Bossion Amaury , Nicolas Julien
Published: December 2023

Polymer prodrugs are based on the covalent linkage of therapeutic molecules to a polymer structure which avoids the problems and limitations commonly encountered with traditional drug-loaded nanocarriers in which drugs are just physically entrapped (e.g., burst release, poor drug loadings). In the past few years, reversible-deactivation radical polymerization (RDRP) techniques have been extensively used to design tailor-made polymer prodrug nanocarriers. This synthesis strategy has received a lot of attention due to the possibility of fine tuning their structural parameters (e.g., polymer nature and macromolecular characteristics, linker nature, physico-chemical properties, functionalization, etc.), to achieve optimized drug delivery and therapeutic efficacy. In particular, adjusting the nature of the drug-polymer linker has enabled the easy synthesis of stimuli-responsive polymer prodrugs for efficient spatiotemporal drug release. In this context, this review article will give an overview of the different stimuli-sensitive polymer prodrug structures designed by RDRP techniques, with a strong focus on the synthesis strategies, the macromolecular architectures and in particular the drug-polymer linker, which governs the drug release kinetics and eventually the therapeutic effect. Their biological evaluations will also be discussed.
Active droplets through enzyme-free, dynamic phosphorylation
Authors: Poprawa Simone , Stasi Michele , Wenisch Monika , Kriebisch Brigitte , Sastre Judit , Boekhoven Job
Published: December 2023

Life continuously transduces energy to perform critical functions using energy stored in reactive molecules like ATP or NADH. ATP dynamically phosphorylates active sites on proteins and thereby regulates their function. Inspired by such machinery, regulating supramolecular functions using energy stored in reactive molecules has gained traction. Enzyme-free, synthetic systems that use dynamic phosphorylation to regulate supramolecular processes do not exist. We present an enzyme-free reaction cycle that consumes phosphorylating agents by transiently phosphorylating amino acids. The phosphorylated amino acids are labile and deactivate through hydrolysis. The cycle exhibits versatility and tunability, allowing for the dynamic phosphorylation of multiple precursors with a tunable half-life. Notably, we show the resulting phosphorylated products can regulate the peptide’s phase separation, leading to active droplets that require the continuous conversion of fuel to sustain. Our new reaction cycle will be valuable as a model for biological phosphorylation but can also offer insights into protocell formation.
Modern concept of differential diagnosis of colitis: from G.F. Lang to the present day. A review
Authors: Parfenov Asfold I. , Kagramanova Anna V. , Khomeriki Sergey G. , Kulakov Dmitrii S.
Published: December 2023

The aim of the article is to improve the differential diagnosis of specific and nonspecific inflammatory bowel diseases. In Russia, this scientific direction is associated with the name of G.F. Lang, who performed in 1901–1902 the study „On ulcerative inflammation of the large intestine caused by balantidiasis“. The etiology of specific colitis is associated with infection with parasites, bacteria and viruses that cause inflammation of the intestinal wall, diarrhea, often with an admixture of mucus, pus and blood. Specific colitis (SC) may be accompanied by fever, abdominal pain, and tenesmus. Bacterial colitis is commonly caused by Salmonella, Shigella, Escherichia coli, Clostridium difficile, Campylobacter jejuni, Yersinia enterocolitica, and Mycobacterium tuberculosis. Viral colitis is caused by rotavirus, adenovirus, cytomegalovirus, and norovirus. Parasitic colitis can be caused by Entamoeba histolytica and balantidia. In gay people, SC can cause sexually transmitted infections: Neisseria gonorrhoeae, Chlamydia trachomatis, and treponema pallidum, affecting the rectum. Stool microscopy, culture, and endoscopy are used to establish the diagnosis. Stool culture helps in the diagnosis of bacterial colitis in 50% of patients, and endoscopic studies reveal only nonspecific pathological changes. Differential diagnosis of SC should be carried out with immune-inflammatory bowel diseases (ulcerative colitis, Crohn's disease, undifferentiated colitis), radiation colitis and other iatrogenic bowel lesions. The principles of diagnosis and therapy of inflammatory bowel diseases associated with various etiological
Vascular complications of diabetes mellitus worldwide and in Russia: The path of 100 years. A review
Authors: Shestakova Marina V. , Severina Anastasia S.
Published: December 2023

With the discovery and introduction of insulin, the "palette" of life-threatening conditions for patients with diabetes mellitus has changed dramatically: from diabetic coma of the "pre-insulin era" to severe vascular complications in the modern period. The key risk factors for diabetic angiopathies in diabetes mellitus are poor glycemic control in combination with a long course of the disease. Over the past 30 years, there has been a downward trend in the incidence of late vascular complications of diabetes both worldwide and in Russia. In particular, the frequency of cardiovascular events (myocardial infarctions, strokes, amputations) decreased, and the incidence of several other complications, such as diabetic retinopathy and neuropathy, stabilized. However, the incidence of chronic kidney disease and chronic heart failure is still increasing. The Joslin Medal, awarded to patients over 50, 75 and even 80 years of life with diabetes, reflects success in the fight against this disease.
Current antiretroviral therapy: A review
Authors: Kravchenko Alexey V. , Maleyev Viktor V.
Published: December 2023

The article presents an overview of clinical recommendations for currant antiretroviral therapy. Currently, the current preferred first-line antiretroviral therapy regimens are combinations of 2 or 3 antiretroviral drugs (ARVs) in one tablet with a frequency of administration 1 time per day and, as a rule, include drugs of the 2nd generation (integrase inhibitors or non-nucleoside reverse transcriptase inhibitors). These schemes have high efficiency and a good genetic barrier in the development of HIV resistance mutations. HIV protease inhibitors are used as alternative regimens. Schemes with the least number and spectrum of side effects, no effect on metabolic processes and minimal drug interactions have advantages. Switching patients to injectable therapy regimens with a frequency of administration of drugs once every 2 months can significantly improve the quality of life of patients and, accordingly, adherence to their treatment. The development and introduction of new classes of ARVs into clinical practice ensures the suppression of HIV replication in most patients with HIV strains resistant to drugs of the main groups of ARVs (nucleoside/nucleotide reverse transcriptase
Ways for reducing mortality from cardiovascular diseases: A review
Authors: Boytsov Sergey A.
Published: December 2023

Ways for reducing mortality from cardiovascular diseases The article analyzes the possible ways to further reduce cardiovascular disease mortality in the Russian Federation by eliminating shortcomings and pitfalls, introducing known but not used opportunities, and new organizational and medical technologies based on the accumulated experience of "best practice".
V. N. Vinogradov Faculty Therapy Clinic of Sechenov University: the flagship of the therapeutic service of the Russian Federation. A review
Authors: Fomin Victor V. , Blagova Olga V. , Morozova Natalia S. , Serdyuk Margarita I. , Royuk Valeriy V.
Published: December 2023

The history of the Faculty Therapy Clinic of Sechenov University is presented. The stages of the formation of its therapeutic school are discussed. Diagnostic and therapeutic methods first developed and implemented in the clinic are described in detail.
Food inequality in Kharkiv during the war: an overview of causes, manifestations and ways to overcome
Authors: Boiko Dmytro , Usenko Diana
Published: December 2023

The article presents one of the aspects of the working theme of the Kharkiv team of the Fusilli project, namely, a general overview of the concept and phenomenon of food inequality as one of the forms of manifestation of general social inequality, as a process that outlines unequal and uneven access for different groups in different periods of time to benefits and resources necessary for the full reproduction of vital forces and provision of opportunities for personal development. Food inequality is problematized as a concept necessary to describe and explain the state of the city of Kharkiv under the conditions of a full-scale invasion at three stages: (1) the availability of food products as such in the Kharkiv region; (2) access to goods, that is, the very possibility of purchasing goods in one or another quantity and quality; (3) use of the goods, which are related to the possibility of consumption of the necessary goods. The concept and phenomenon of food inequality is correlated with other forms of social inequality, and an instrumental definition of the main causes and manifestations of food inequality is proposed. A general assessment of the state of food inequality in Ukraine is given and preliminary results of the author's sociological research are given. The article also reviews international, national and local initiatives aimed at solving the problem of food inequality, in particular the policies of central and local authorities, grant programs from foreign companies, the activities of local and international public, volunteer and charitable organizations. The authors come to the conclusion that the possibilities of solving the problem of food security exclusively by economic means and tools are limited, since it is a complex problem that requires a systematic solution involving not only economic, but also political, ecological, cultural, informational, etc. levers.
Culture of «green» festivals in urbanized space: the case of «Kharkiv Green Urban Fest 2023»
Authors: Deineko Oleksandra , Zaporozhchenko Ruslan , Yashkina Daria
Published: December 2023

The article is devoted to highlighting the culture of festivals on the example of the urbanized space of the city of Kharkiv through the prism of the ecological festival «Kharkiv Green Urban Fest 2023», which was held by the School of Sociology at V.N. Karazin Kharkiv National University on June 17, 2023, based on the cultural space «YermilovCenter». The festival was held as part of the implementation of the international research project FUSILLI (Fostering the Urban Food System Transformation through Innovative Living Labs Implementation) at the School of Sociology of V.N. Karazin Kharkiv National University, funded by the European Union’s Horizon 2020 Research and Innovation Program under the grant agreement №101000717. The main objective of the festival was to showcase local initiatives that focus on responsible consumption, farming, recycling, social entrepreneurship, healthy eating, and sustainable development.

In this article, based on small semi-structured interviews with event participants, we propose a conceptualization of festival culture and identify its inherent features, at the normative-value and structural-functional levels. Using some methodological approaches, we propose to consider the culture of festivals as an example of spontaneous social (inter)action, during which subjects are involved in the construction of a new social reality, which can, although not necessarily, be exported to their own environment. This example of social (inter)action helps to disseminate certain values and beliefs that can be shaped by interactional actions. In addition, we demonstrate the importance and necessity of such events to promote the values of responsible consumption and the development of the city’s food system.
THE UKRAINIAN LANGUAGE PROJECT OF UKRAINIAN PHILOSOPHY AND ITS "LEXICON OF UNTRANSLATABLES"
Authors: Korabliova Nadiia , Chmil Hanna
Published: December 2023

The illustrations of the translation of "untranslatables" considered in the article prove the idea that they are not an inconvenience, but a form of enrichment of philosophy, which formats the line of its cumulative development through the production of concepts (Gilles Deleuze, Felix Guattari "What is philosophy?"), as a way of existence of modern philosophy. The concept is determined not only by tradition and the ability to use the "lexicon of untranslatables", but also by language, cultural and political contexts. We substantiate the thesis that the format of the concept dismantles the idea of ​​such a philosophy that is able to speak only in universal languages ​​and emphasize the importance of local philosophies, to which the Ukrainian one belongs. Such importance is manifested in the fact that: national philosophies demonstrate local features of European philosophy; is the transformation and approbation of its ideas in national contexts; creates that "lexicon of untranslatables", the mastery of which teaches philosophy to speak national languages; the national language acquires the ability to become a means of expressing philosophical ideas (Dmytro Chyzhevsky, Oleksander Potebnia); the "lexicon of untranslatables" is modified by the dominant values ​​of the time, embodied in the mentality and culture of the people.

The historical examples and analogies given in the text of the objective symbolic fixation of the translation of philosophical terms in national languages ​​allow us to clarify the options of the linguistic prerequisites of philosophical theories expressed in national languages, and are an argument against the monolingualism of philosophy. The modern translation of "untranslatables" works within the epistemological field of the philosophy of language, shifting the focus from the language code to the discourse, the latter is not a necessary condition for understanding the language, but is a source of destruction of communication or development of those rules, following which makes communication effective. Rejecting the universalist approach and focusing on national strategies, we consider language as a primary source that "pressures" the philosopher, which means that it implies a critique of traditional linguistic ideas about language. The trending topic is the concepts of cultural imperialism, which with the beginning of Russia's aggression against Ukraine became a fact of life for Ukrainians, and the Ukrainian language turned into a weapon of support for this aggression.
LANGUAGE EXPANSION AS A NECESSARY MEASURE FOR THE (ECONOMIC-)IMPERIALIST RELATIONS
Authors: Panov Volodymyr
Published: December 2023

In this article, we try to show how language expansion, language strategies, etc. are envisaged in various theories of (economic) imperialism. In order to establish this, we turn to economic interpretations of imperialism, namely Hobson and Lenin, world-system analysis (Wallerstein, Amin, Arrighi) and the Empire theory of Hardt and Negri. By studying them, we singled out the key characteristics of imperialism that are found in most (economic) theories of imperialism, namely: (1) the creation of market relations (and the market in general) between the metropolis/core/imperial country and the colony/periphery/subjugated territory, (2) the presence of an advantage in this relations for the metropolis/core/imperial country, which is most often described as a monopoly position, (3) finally, often, but not always, the economic exploitation of the conquered territories is stated. We note that the market is (in particular) a communicative phenomenon, which at least involves the possibility of understanding between the buyer and the seller; thus, language appears as a condition that enables exchange and even consumption. We demonstrate that the popularization and expansion of the language also means the imposition of competition; therefore, capital competition should automatically imply language competition, and the intertwining of markets also the "intertwining" of languages (and vice versa). Using the example of the Commonwealth, we show how language is capable of forming spheres of influence and the centre of gravity of capital. With reference to Rancière, we note that lingua franca projects are capable of both inclusion in the economic system (regions, countries, etc.) and exclusion from it (poor stratas). Finally, we draw attention to the fact that language is capable of acting as cultural capital in Bourdieu's understanding, and therefore capable of being converted into economic capital.
INFORMATION SOCIETY AND NEW GLOBAL ETHICS
Authors: Tolstov Ivan , Danilian Vadym
Published: December 2023

The article is dedicated to analyzing socio-cultural and ethical changes occurring in the modern information society under the influence of globalization processes. The main aim of the research is to analyze cultural transformations in the sphere of information society ethics. In examining these changes, the authors utilize theoretical concepts from leading researchers in the field of information society and ethics, including D. Bell, J. Baudrillard, M. Castells, R. Florida, at al.

The article focuses on changes not only oriented towards technological aspects and the proliferation of information but also on the complex aspects of human interaction: the ability to create and transmit ethical values from generation to generation while considering existential priorities and moral norms.

The authors regard the information society as a new socio-cultural reality that necessitates the development of a new global ethics. Such an ethics should take into account the global experience in the realm of morality and the necessity for democratizing the information society.

The main emphasis of the article is directed towards interactive, networked communication as a key element of interaction, diverse forms of social dialogue, and methods of democratizing social relations through new technologies. In this context, the authors highlight the significance of Generation Z as a new creative class within the information society, serving as a subject of global ethics. This generation possesses new communicative skills and the ability to propose new strategies and forms of ethical behavior to adapt within the changing information society.

In the conclusions of the article, the authors underscore that a new global ethics requires norms capable of aligning national, particular values with global universal ethical values, including ecological, humanistic, and human-centered values, ensuring their accessibility through the democratization of the information society. The methodological basis for such ethics could be Kantianism, fostering the harmonization of intergenerational interactions in the context of information society development.
DECENTRATION OF AUTHENTIC AUTHORITATIVE AUTHOR
Authors: Khrabrov Heorhii
Published: December 2023

The article manifests and analyzes the process of decentration of the Author, which corresponds to a number of trends, such as: decentration of the subject, dividualization, decentralization of information systems, etc., which determine contemporary transformations of the Lifeworld of a human, who appears precisely as a decentralized, multilayered, split, multiple being. It is noted that the model of authorship, which was constituted according to the concept of a centered/holistic subject/individual, which, in particular, is embodied in copyright, needs to be reconsidered. The meaning of such a model, which is conceptualized in the figure of "authenticity of an authoritative author", is reduced to the creation of Surplus Value with behalf of the author of the product/work/goods. The article presents the stages of decentration of the Author, authority and authenticity, which are personified by the figures of S. Kierkegaard, M. Duchamp, and R. Stallman. For Kierkegaard, it is fundamental to separate the function of the author from authority and the formation of existence/singularity, which, in particular, is embodied in his use of pseudonyms. Duchamp problematizes the author as a producer of a product, contrasting him with the practice of using ready-made objects, and contrasts the tradition of the author's signature with the multiplication of names/signatures. Duchamp exposes the exploitative essence of work even in relation to artistic creativity, manifesting as an alternative to laziness/"lazy activity", which allows shifting the emphasis from the production of things to the process of becoming subjectivity. In the end, the author as integrity and unity loses its meaning in the context of the development of contemporary technologies and network communication. Stallman presents a strategy of friendly exchange of free software instead of selling it based on copyright (intellectual property). This is what should increase productive activity and free up time, and in the long run, creativity should hardly be distinguished from laziness. These three examples testify to the possibility and necessity of overcoming the repressive component of authorship and copyright as a way of controlling/restricting human life, which is not a totality, does not have substantial authenticity, does not require authority, and does not focus on authorship.
ON THE METAPHYSICS OF QUANTUM ENTANGLEMENT
Authors: Tiaglo Oleksandr
Published: December 2023

Concept of quantum entanglement, its role in physics, philosophy, and in updating general worldview are studied in this article. It is pointed out that Schrodinger introduced this concept and some derivatives from it into description of physical reality in the 1935 article in the context of discussion around the Einstein-Podolsky-Rosen thought experiment, but in the related 1936 publication he did not use them. Taking into account the concepts of a mixture and statistical operator, which were introduced by von Neumann and borrowed by Schrödinger, it is shown that the concept of entanglement is not necessary in quantum mechanics unconditionally. At a certain moment of development of the complex quantum systems theory, this concept and its derivatives served as not very successful substitutes for the concepts of a mixture, situation of a mixture.

Comparative analysis of some Schrödinger’s, von Neumann’s, and Landau’s theoretical works concludes that imagination of a complex quantum system as a quasi-mechanical aggregate was gradually being overcome; its objective wholeness was being substantiated instead. Therefore, wholeness is inherent not only to quantum phenomena, but also to quantum systems by itself, objectively. By the essence, just the attempt to think this circumstance had brought into life the concept of quantum entanglement. The concept of a mixture and its substitutes – the concepts of entangled state, entanglement, etc. – have not only the scientific but some metaphysical meaning as well: they prove the possibility of rational thinking of wholeness, the reasonableness and effectiveness of rational holism. Therefore, the metaphysics of quantum entanglement in its correct understanding is a manifestation of the rational holism metaphysics.

Complete explanation of the Einstein-Podolsky-Rosen thought experiment requires consideration of both these appearances of the quantum wholeness. One can say the essential result of long-term discussion of the EPR experiment is the exhaustive recognition of the quantum reality wholeness.

A row of generalizations achieved by A. Alexandrov, I. Tsekhmistro, and D.Bohm are considered. Together with the completed study of the concept of quantum entanglement or Bohr's substantiation of the concept of undivided quantum phenomenon, they support irreducibility of physical reality, the Universe in general to any set of Democritian atoms and their countless combinations, aggregates. All this enriches and improves the understanding of the Universe as a real wholeness. Perhaps, this understanding will be newest substitution for the hitherto popular worldview in the spirit of Democritus.
MEMIRONY: REBOUND OF RELATIONSHIPS IN MEMES
Authors: Zahurska Nataliia
Published: December 2023

The study researches the mutual influences of memes and love or sexual relationships. It displays, that, on the one side, the topic of relationships is one of the most common and in many ways defines Internet memetics as a whole. On the other side, creating and sending memes became an important part of contemporary relationships and support them. Memes help to remember key point of successful relationships and this knowledge is a constituent of their background and allow develop them and, at the same time, strengthens their sustainability through good emotional context. Regarding this, the study displays, that memetic humour, even in its most sharp or black forms plays a positive role. Based on this the research introduces and considers the new concepts of memirony and metahumour. So, the study affirms, that memes are part of post-postmodern eventuality, more relatable and sincere than postmodern. Relatable, truth-to-life memes, in comparison with too intellectual memes, helps maintain closer relationships through genuine love game. The research put special attention to a linguistic component of memes, meme «languages» in particular. Except for basic memetic conceptions by Limor Shifman, Douglas Hofstadter, Susan Blackmore, etc., and the cognitive approach of Daniel Dennet, the study is based on the conception of love as a comedy by Alenka Zupančič and laughter as a linguistic appearance by Mladen Dolar, the conception of the relationships between sincerity, comedy and charm by Graham Harman, etc. The research was conducted on the material of Internet memes, as well as other works of contemporary art that demonstrate the importance of humour for relationships.
PLATO`S MYTHS
Authors: Prokopenko Volodymyr
Published: December 2023

The article examines the question of Plato's concern with mythology. The author claims that Plato was an uncompromising critic of traditional myth and poetic myth-making, because such myths distorted the real images of the gods and their actions. Poetic myths do not reflect well on education, so their creators should, as Plato believed, be removed from a just state. The article draws attention to the fact that Plato himself was a significant mythmaker - he tells many important philosophical ideas precisely in the form of myths. The author analyzes the reasons for Plato's appeal to myth, defines the functions performed by myth in Plato's dialogues, the importance of Platonic myth-making for philosophy and mythology. It is noted that Plato uses myth as a tool of expressiveness, considers it as an effective means of persuasion. On the other hand, the article proves the thesis that the Platonic myth is a way to express the deep problems of existence that cannot be grasped by the human mind. Therefore, Plato's myths tell about what happens in the sky, under the Earth in Hades, in the distant past. The article concludes that a substantial reform of the entire ancient Greek mythology takes place in the Platonic myth-making activity. Plato combines myth with rational thinking, with the Logos. For Plato, a myth is a rationalized myth in which not only the cosmos acquires a divine dimension, but also man and his world, the polis. This is how the dialectician becomes a creator of myths. Plato, the article claims, becomes a mythmaker because it is extremely important for him to find a support for man in the human soul, as reliable and eternal as the divine cosmos of traditional myths used to serve.
PAUL LEUCKFELD (1859–1930) AND THE INDUCTIVE PHILOSOPHY OF WILLIAM WHEWELL (1794–1866)
Authors: Abashnik Volodymyr
Published: December 2023

This article presents a little-studied issue of critical analysis of the main provisions of the inductive philosophy of the English thinker William Whewell (1794–1866) within the framework of university philosophy, in particular in the publications of the famous Kharkiv professor Pavlo Emilievych Leuckfeld (1859–1930). In this context, the main stages of Pavlo (Paul) Leuckfeld's creative and scientific path are indicated at the beginning, in particular his studies at the 2nd Kharkiv Gymnasium (1871–1878) and at the Faculty of History and Philology of Kharkiv University (1878–1883). Further, attention is focused on his teaching activities at Kharkiv University (1884–1918), in particular on his fellowship since 1884, teaching the history of philosophy and logic as a private docent (since 1886), extraordinary professor (since 1893) and ordinary professor of philosophy (since 1899). His participation in international philosophical and psychological congresses, in particular in Munich (1896), Geneva (1904), Heidelberg (1908), and the peculiarities of his scientific fellowship at the University of Graz (Austria) with the authoritative professor Alexius Meinong are also indicated. In addition, attention is paid to the main features of Pavlo Leuckfeld's teaching and publications during his “Simferopol (Crimean) period”, when he was a professor of philosophy and psychology there.

Pavlo Leuckfeld's publications were devoted to three main areas: 1) logic and the history of logic, 2) psychology and pedagogy, and 3) the history of philosophy. Among the publications of the first direction, two of his monographs were of great importance: “Various Trends in Logic and the Main Tasks of this Science” (1890) and “Logical Doctrine of Induction in the Main Historical Moments of Its Development” (1896). In these works, he analyzed the relevant positions of famous ancient and English philosophers (Aristotle, Francis Bacon, John Herschel, and John Stuart Mill). An important place in his analysis is occupied by the critical interpretation of the inductive philosophy of William Whewell, presented in particular in the third edition of the three-volume work “History of the Inductive Sciences, from the Earliest to the Present Time” (1857). In this sense, the features of this work of the English philosopher were first pointed out, and then the main theses of Paul Leuckfeld in presenting his understanding of the position of William Whewell.
The Trypillia in the historiosophy of Yury Lypa
Authors: Kucherenko Svitlana
Published: December 2023

The purpose of the article. Elucidation of the views of the Ukrainian publicist, historiographer, geopolitician Yury Lypa (1900–1944) on Trypil archaeological culture, which were formed mainly under the influence of the Ukrainian archaeologist, ethnologist, and art critic Vadym Shcherbakivskyi (1876–1957).

The research methodology involves the application of the principles of critical analysis and comparison.

Scientific novelty. Borrowings and innovations regarding the interpretation of Tryplian archaeological culture in Lypov historiosophy are taken into account. Yuri Lypaʼs reasoning regarding the significance of the culture of painted ceramics in the ethnogenesis, character, traditions, even in the forms of social organization and political actions of Ukrainians, as well as the social significance of the results of Trypilian researches, is clarified. The Tripoli component of Yuri Lypaʼs concept in his book «The Destiny of Ukraine» (1938) is singled out, the relevant terms and concepts used in the concept are identified and interpreted. The conclusions of modern Tripille studies are given incidentally.

Conclusions. The proposed article is one of the attempts to answer the question: Was Yuri Lypa a scientist or a creator of a national myth?
Byzantine Studies in dissertations produced by Ukrainian scholars, 2012–2022 (Historical Sciences)
Authors: Domanovska Maryna , Domanovskyi Andriy
Published: December 2023

The article reviews the dissertations on Byzantine studies, which have been defended in Ukraine over the past decade in historical specialties within the field of “historical sciences”. Byzantine studies in Ukraine, as in previous periods, continue to develop in institutional centers, among which are V. N. Karazin Kharkiv National University, M. S. Grushevsky Institute of Ukrainian Archeography and Source Studies NASU, Ivan Franko National University of Lviv, National Reserve “Sophia of Kyiv”, I. I. Mechnikov Odessa National University etc. The range of dissertations of an interdisciplinary nature is expanding, in particular, historical, theological, historical and philosophical topics are gaining popularity, and art criticism and musicology are becoming popular.

The review identifies the reasons for the reduction in the number of defended dissertations in Byzantine studies during 2012–2022 in the comparison to previous periods. However, the studies presented in the review are original, based on the latest methods and achievements of world science, and they also determine further vectors of the development of Ukrainian Byzantine studies in the near future.
The Possibilities of Modern Client-Centered and Experiential Psychotherapy
Authors: Kocharian Oleksandr , Barinova Nataliia , Barinov Sergey A.
Published: December 2023

In Ukraine, important processes are underway to identify those areas of psychotherapy that deserve official recognition by law. The official recognition of psychotherapeutic methods and techniques is associated with the fact that they are recognized as clinically and statistically effective. Such psychotherapy is reimbursed by insurance and is actively promoted in training courses, often "at the expense of other methods of psychotherapy." The psychotherapeutic procedure itself is becoming more and more standardized and impersonal, conforming to a protocol. The fate of client-centered and experiential psychotherapy (PCE-therapy) is not so easy in the world: evidence of its effectiveness is not reflected in the NICE (National Center for Collaboration in Mental Health) guidelines for depression and schizophrenia, which to some extent determine health policy. Therefore, there are widespread prejudices about the ineffectiveness of this type of therapy: it is not effective for severe mental illness, crisis states, specific phobias and traumas, behavioral problems, for those clients who need a directive approach, for assessing and diagnosing clients, etc. The article presents specific studies of the effectiveness of client-centered and experiential psychotherapy for specific symptoms (anxiety, depression, schizophrenia, borderline personality disorders, and some somatic disorders), as well as data from a meta-analysis of the effectiveness of client-centered and experiential therapy. PCE-therapy proved to be highly effective according to the criteria: "before-after" treatment; 2) "treatment-no treatment"; 3) "comparison with other types of psychotherapy" - the data obtained are generally statistically and clinically equivalent in terms of effectiveness to other methods of psychotherapy. PCE therapy proved to be the most effective in the following cases: interpersonal problems, self-harming behavior, coping with chronic somatic diseases, psychosis. It turned out that cognitive behavioral therapy (CBT) has mixed benefits compared to PCE therapy. However, Elliott et al. note that, firstly, these "studies were mostly performed by CBT therapists" and, secondly, "low-quality versions of PCE therapy were used as comparison conditions". The most effective methods of PCE therapy were EFT and PCT. A list of approaches included in PCA-therapy is given, and their general characteristics are given.
A Story About Hibuki - A Psychologist's Instruments in Work with Children's Trauma
Authors: Nauchitel O.D. , Kharchenko A.O.
Published: December 2023

Problem definition. The uncertainty of the consequences of situations related to stressful situations for the child's psyche actualizes the issue of introducing new approaches, methods and tools of psychological influence that would contribute to the preschooler's ability to overcome stress in a constructive way. Problem analysis. Childhood psychological trauma leaves its mark on the subconscious, can shape a person's worldview, beliefs, and identification of the self. And since trauma affects the levels of primary safety, it creates very powerful patterns in the mind. Signs of childhood trauma include mood swings, guilt, anxiety, feelings of abandonment, confusion and impaired concentration, and withdrawal. The conceptualization of traumatic experience is widely presented in scientific literature: theories of traumatic emotional experience (O.S. Kocharyan, R. Lanius, M. Massey, R. Hammer), conceptual foundations of the subverbal model of client-centered psychotherapy (O.S. Kocharyan), theories and typologies of infantile traumas (Johnson St. M., Burbo L., etc.), theoretical positions of procedural-experiential and emotionally-focused psychotherapy (Greenberg L. and Elliott R.), psychoanalytic theory according to Freud Z., ideas about the formation of early maladaptive schemes (Boterhoven de H., Christopher W., Fassbinder E., Hayes C., Katrina L., Yong J.) and others. However, solving many complex problems remains relevant, one of which includes psychological assistance to the most vulnerable population groups in extreme situations, one of which includes children and work with current traumatic experiences. The purpose of the study is to develop and test a multifunctional tool for working with childhood trauma in conditions of long-term traumatic circumstances. Conclusions. The stories about Hibuki, through which the child identified with the hero of the story, contribute to the restoration of internal mechanisms of the psyche, which help the process of restoring the child's psychological health. A psychologist can use these stories both to rehabilitate a child's psyche and to diagnose his or her emotional state.