bluuebunny/crossref_metadata_2025 huggingface dataset:
The validation of the Minnesota Job Satisfaction Questionnaire in selected organisations in South Africa
Authors: Buitendach Johanna H. , Rothmann Sebastiaan
Published: June 2009

The objectives of this study were to assess the construct equivalence of the Minnesota Job Satisfaction Questionnaire (MSQ), and to investigate the manifestation of job satisfaction at selected organisations in South Africa. A cross-sectional survey design with a random sample (N = 474) was used. The MSQ and a biographical questionnaire were administered. The results confirmed a two-factor model of job satisfaction, consisting of extrinsic job satisfaction and intrinsic job satisfaction. Exploratory factor analysis with target rotations conf rmed the construct equivalence of scales for the black and white groups. The results obtained from comparing job satisfaction levels of various demographic groups showed that practically significant differences existed between the job satisfaction of different age and race groups.
In Vitro GEF and GAP Assays
Authors: Eberth Alexander , Ahmadian Mohammad Reza
Published: June 2009

Small GTPases act as tightly regulated molecular switches governing a large variety of critical cellular functions. Their activity is controlled by two different biochemical reactions, GDP/GTP exchange and GTP hydrolysis. These very slow reactions require catalysis in cells by two kinds of regulatory proteins. While the guanine nucleotide exchange factors (GEFs) activate small GTPases by stimulating the slow exchange of bound GDP for the cellularly abundant GTP, GTPase‐activating proteins (GAPs) accelerate the slow intrinsic rate of GTP hydrolysis by several orders of magnitude, leading to inactivation. There are a number of methods that can be used to characterize the specificity and activity of such regulators, to understand the effect of binding on the protein structure, and, ultimately, to obtain insights into their biological functions. This unit describes (1) detailed protocols for the expression and the purification of small GTPases and the catalytic domains of GEFs and GAPs; (2) preparation of nucleotide‐free and fluorescent nucleotide‐bound small GTPases; and (3) methods for monitoring of the intrinsic and GEF‐catalyzed nucleotide exchange as well as intrinsic and GAP‐stimulated GTP hydrolysis. Curr. Protoc. Cell Biol. 43:14.9.1‐14.9.25. © 2009 by John Wiley & Sons, Inc.
Cubic‐plus‐association equation of state for water‐containing mixtures: Is “cross association” necessary?
Authors: Li Zhidong , Firoozabadi Abbas
Published: June 2009

We have recently proposed an accurate version of the cubic‐plus‐association (CPA) equation of state (EOS) for water‐containing mixtures which combines the Peng‐Robinson equation (PR) for the physical interactions and the thermodynamic perturbation theory for the hydrogen bonding of water molecules. Despite the significant improvement, the water composition in the nonaqueous phase is systematically underestimated for some systems where the nonwater species are methane and ethane at very high pressures, unsaturated hydrocarbons, CO2, and H2S. We attribute the deficiency to the neglect of the “cross association” between water and those nonwater molecules. In this work, the accuracy is drastically improved by treating methane, ethane, unsaturated hydrocarbons, CO2 and H2S as “pseudo‐associating” components and describing the cross association with water in the framework of the perturbation theory. It is shown that the cross association is more significant for the nonaqueous phase. In addition to binary mixtures, reliable predictions are achieved for H2O/C1/CO2/H2S quaternary mixture in two and three phases. © 2009 American Institute of Chemical Engineers AIChE J, 2009
A need for classification agreement: Perspectives from an advocacy group
Authors: Richter Mary Kaye
Published: June 2009

There is a need to focus on the classification of the ectodermal dysplasia syndromes to reach consensus on a classification that satisfies all interested parties. However, whatever scheme is developed, it will have far‐reaching application for other groups of disorders for which classification is complicated by the number of interested parties and advances in diagnostic acumen. Consensus among interested parties is necessary for communication among the parties whether it be for equitable distribution of funds, correctness of diagnosis and treatment, or focusing research efforts. Classification of the ectodermal dysplasia syndromes will enable advocacy organizations like the National Foundation for Ectodermal Dysplasias to better serve constituents, to use limited resources more effectively, to move research forward, to find cures and to bring continued hope for the future to those we serve. Having international agreement on these issues will enable all of our organizations to move forward with confidence. © 2009 Wiley‐Liss, Inc.
From ectodermal dysplasia to selective tooth agenesis
Authors: Mues Gabriele I. , Griggs Rachel , Hartung Andrew J. , Whelan Greg , Best Lyle G. , Srivastava Anand K. , D'Souza Rena
Published: June 2009

The history and the lessons learned from hypohidrotic ectodermal dysplasia (HED) may serve as an example for the unraveling of the cause and pathogenesis of other ectodermal dysplasia syndromes by demonstrating that phenotypically identical syndromes (HED) can be caused by mutations in different genes (EDA, EDAR, EDARADD), that mutations in the same gene (EDA) can lead to different phenotypes (HED and selective tooth agenesis) and that mutations in genes further downstream in the same signaling pathway (NEMO) may modify the phenotype quite profoundly (incontinentia pigmenti (IP) and HED with immunodeficiency). But it also demonstrates that diligent phenotype characterization and classification is extremely helpful in uncovering the underlying genotype. We also present a new mutation in the EDA gene which causes selective tooth agenesis and demonstrates the phenotype variation that can be encountered in the ectodermal dysplasia syndrome (HED) with the highest prevalence worldwide. © 2009 Wiley‐Liss, Inc.
Ectodermal dysplasias: An overview and update of clinical and molecular‐functional mechanisms
Authors: Priolo Manuela
Published: June 2009

The ectodermal dysplasias (EDs) are a large and complex group of disorders. In various combinations, they all share anomalies in hair, teeth, nails, and sweat gland function. The anomalies affecting the epidermis and epidermal appendages are extremely variable. Many are associated with malformations in other organs and systems. Clinical overlap is present among EDs. Few causative genes have been identified, to date. Most of the EDs present multisystem involvement with abnormal development of structures also derived from mesoderm. In the last few years, it has become evident that gene expression in the EDs is not limited to the ectoderm and that there is a concomitant effect on developing mesenchymal structures, with modification or abolition of ectodermal–mesenchymal signaling. It is possible to approach this group of diseases basing on functional and molecular findings and to begin to explain the complex clinical consequences of mutations affecting specific developmental pathways. We have reviewed the molecular basis of ectodermal dysplasias applying this new clinical–functional classification. For each subset of the identified ED, we will now describe the genes and related proteins involved in terms of: (1) structure of the genes and their role in differentiation of the epidermis and the ectodermal derivatives; (2) genotype–phenotype correlation. © 2009 Wiley‐Liss, Inc.
Psychosocial functioning and quality of life in children and families affected by AEC syndrome
Authors: Lane Mariella M. , Dalton William T. , Sherman Sandra A. , Bree Alanna F. , Czyzewski Danita I.
Published: June 2009

Ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) syndrome, also known as Hay–Wells syndrome, is a rare genetic condition that results in abnormalities of the skin, hair, nails, and teeth and requires frequent self‐management and medical care. We sought to describe the psychological adjustment and quality of life in children and adolescents with AEC syndrome, as well as the impact of the child's illness on their families. The sample included 18 children and adolescents with AEC syndrome and their parents who attended the International Research Symposium on AEC syndrome. Parents completed standardized self‐report questionnaires about child and family functioning and participated in a semi‐structured interview about the child's cognitive and social functioning and the impact of AEC syndrome on the child and family. Children completed standardized self‐report questionnaires of psychosocial functioning and quality of life. Overall, results reflected a range of functioning across children and families, with some families reporting few ill effects of the condition and others describing reduced quality of life and negative impact on child and family. Identifying the domains that may be impacted should help clinicians better screen for problems in functioning of children affected by AEC syndrome and their families. © 2009 Wiley‐Liss, Inc.
Relationship between sexual interactions and the timing of the fertile phase in captive female Japanese macaques (Macaca fuscata)
Authors: Garcia Cécile , Shimizu Keiko , Huffman Michael
Published: June 2009

Japanese macaques live in multi‐male/multi‐female social groups in which competition between males, female mate choice, and alternative male mating strategies are important determinants of mating and reproductive success. However, the extent to which adult males rely on female behavior to make their mating decisions as well as the effect of social rank on mating success are not clear as results are inconclusive, varying from study to study. In this study, we combined behavioral and endocrine data of 14 female Japanese macaques to examine the relationship between ovarian cycle phase and frequency of sexual behaviors, and to investigate how social rank influences sexual behavior in this species. We found that there was no increase in female proceptive behaviors during the fertile phase of the ovarian cycle, suggesting that female behaviors did not clearly signal the probability of conception. In spite of that, the frequencies of ejaculatory copulations were highest during this phase, indicating that the attractivity of females increased significantly during the period with higher probability of conception. Males, and especially the highest ranking male, were able to discriminate females nearing ovulation and to concentrate their mating effort, implying that the timing of ovulation was not concealed from them. The α male seemed able to monopolize most female matings, which is probably due in part to the low number of females simultaneously ovulating and to the limited number of inconspicuous places that the lower ranking males have to mate with females and avoid α male aggression. All together, these results suggest that different males may have access to different signals of ovulation and/or are differentially restrained as to how they can act on that information. The exact nature of the estrogen‐related cues males use to recognize female reproductive status, and to what extent males use them warrants further investigation. Am. J. Primatol. 71:868–879, 2009. © 2009 Wiley‐Liss, Inc.
Low‐temperature (9°C) AMD treatment in a sulfidogenic bioreactor dominated by a mesophilic Desulfomicrobium species
Authors: Auvinen Hannele , Nevatalo Laura M. , Kaksonen Anna H. , Puhakka Jaakko A.
Published: June 2009

The possibilities for the treatment of low‐temperature mine waste waters have not been widely studied. The amenability of low‐temperature sulfate reduction for mine waste water treatment at 9°C was studied in a bench‐scale fluidized‐bed bioreactor (FBR). Formate was used as the electron and carbon source. The first influent for the FBR was acidic, synthetic waste water containing iron, nutrients, and sulfate, followed by diluted barren bioleaching solution (DBBS). The average sulfate reduction rates were 8 mmol L−1 day−1 and 6 mmol L−1 day−1 with synthetic waste water and DBBS, respectively. The corresponding specific activities were 2.4 and 1.6 mmol SO g VSS−1 day−1, respectively. The composition of the microbial community and the active species of the FBR was analyzed by extracting the DNA and RNA, followed by PCR‐DGGE with the universal bacterial 16S rRNA gene primers and dsrB‐primers specific for sulfate‐reducing bacteria. The FBR microbial community was simple and stable and the dominant and active species belonged to the genus Desulfomicrobium. In summary, long‐term operation of a low‐temperature bioreactor resulted in enrichment of formate‐utilizing, psychrotolerant mesophilic sulfate reducing bacteria. Biotechnol. Bioeng. 2009; 104: 740–751 © 2009 Wiley Periodicals, Inc.
Do physical forces contribute to cryodamage?
Authors: Saragusty Joseph , Gacitua Haim , Rozenboim Israel , Arav Amir
Published: June 2009

To achieve the ultimate goal of both cryosurgery and cryopreservation, a thorough understanding of the processes responsible for cell and tissue damage is desired. The general belief is that cells are damaged primarily due to osmotic effects at slow cooling rates and intracellular ice formation at high cooling rates, together termed the “two factor theory.” The present study deals with a third, largely ignored component—mechanical damage. Using pooled bull sperm cells as a model and directional freezing in large volumes, samples were frozen in the presence or absence of glass balls of three different diameters: 70–110, 250–500, and 1,000–1,250 µm, as a means of altering the surface area with which the cells come in contact. Post‐thaw evaluation included motility at 0 h and after 3 h at 37°C, viability, acrosome integrity, and hypoosmotic swelling test. Interactions among glass balls, sperm cells, and ice crystals were observed by directional freezing cryomicroscopy. Intra‐container pressure in relation to volume was also evaluated. The series of studies presented here indicate that the higher the surface area with which the cells come in contact, the greater the damage, possibly because the cells are squeezed between the ice crystals and the surface. We further demonstrate that with a decrease in volume, and thus increase in surface area‐to‐volume ratio, the intra‐container pressure during freezing increases. It is suggested that large volume freezing, given that heat dissipation is solved, will inflict less cryodamage to the cells than the current practice of small volume freezing. Biotechnol. Bioeng. 2009; 104: 719–728 © 2009 Wiley Periodicals, Inc.
Optimization of the bioprocessing conditions for scale‐up of transient production of a heterologous protein in plants using a chemically inducible viral amplicon expression system
Authors: Plesha Michael A. , Huang Ting‐Kuo , Dandekar Abhaya M. , Falk Bryce W. , McDonald Karen A.
Published: June 2009

Use of transient expression for the rapid, large‐scale production of recombinant proteins in plants requires optimization of existing methods to facilitate scale‐up of the process. We have demonstrated that the techniques used for agroinfiltration and induction greatly impact transient production levels of heterologous protein. A Cucumber mosaic virus inducible viral amplicon (CMViva) expression system was used to transiently produce recombinant alpha‐1‐antitrypsin (rAAT) by co‐infiltrating harvested Nicotiana benthamiana leaves with two Agrobacterium tumefaciens strains, one containing the CMViva expression cassette carrying the AAT gene and the other containing a binary vector carrying the gene silencing suppressor p19. Harvested leaves were both infiltrated and induced by either pressure or vacuum infiltration. Using the vacuum technique for both processes, maximum levels of functional and total rAAT were elevated by (190 ± 8.7)% and (290 ± 7.5)%, respectively, over levels achieved when using the pressure technique for both processes. The bioprocessing conditions for vacuum infiltration and induction were optimized and resulted in maximum rAAT production when using an A. tumefaciens concentration at OD600 of 0.5 and a 0.25‐min vacuum infiltration, and multiple 1‐min vacuum inductions further increased production 25% and resulted in maximum levels of functional and total rAAT at (2.6 ± 0.09)% and (4.1 ± 0.29)% of the total soluble protein, respectively, or (90 ± 1.7) and (140 ± 10) mg per kg fresh weight leaf tissue at 6 days post‐induction. Use of harvested plant tissue with vacuum infiltration and induction demonstrates a bioprocessing route that is fully amenable to scale‐up. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009
Cu[Al(ORF)4] Starting Materials and their Application in the Preparation of [Cu(Sn)]+(n=12, 8) Complexes
Authors: Santiso‐Quiñones Gustavo , Higelin Alexander , Schaefer Julia , Brückner Robin , Knapp Carsten , Krossing Ingo
Published: June 2009

Naked copper…︁?A newly developed simple two‐step route to weakly coordinated CuIstarting materials that were used to prepare novel copper–cyclosulfur adducts, including the first M+–S12complex (see figure, RF= C(CF3)3, C(CH3)(CF3)2, or CH(CF3)2). Reactions with the [Al{OC(CF3)3}4]−counterion mimic gas‐phase chemistry inside a mass spectrometer (to form [Cu(S12)]+).

magnified image

An effective route to stable, almost‐“naked” CuIsalts of weakly coordinating anions (WCAs) of the type [Al(ORF)4]−has been developed. Born–Fajans–Haber cycles and theoretical calculations suggest that this methodology is useful for the generation of CuIsalts regardless of the larger WCA used. The first homoleptic CuI–arene complex [Cu(1,2‐F2C6H4)2]+[Al{OC(CF3)3}4]−(1), the first CuI–methylenechloride complex [Cu(CH2Cl2)Al{OC(CH3)(CF3)2}4] (2), and the donor‐free dimer [CuAl{OCH(CF3)2}4]2(3) were synthesized in quantitative yields by sonicating Li[Al(ORF)4] (RF=C(CF3)3, C(CH3)(CF3)2, or CH(CF3)2), AgF, and a three‐fold excess of CuI in 1,2‐F2C6H4(1) or CH2Cl2(2,3). Substances1–3are good starting materials for further CuIchemistry, and the reaction of1–3with the weak Lewis base cyclooctasulfur gave the first CuI–sulfur complexes of type [Cu(S12)(S8)]+[Al{OC(CF3)3}4]−(4), [Cu(CH2Cl2)(S12)]+[Al{OC(CF3)3}4]−(5), [A1Cu(1,5‐η1,η1‐S8)CuA1] (6; A1=[Al{OC(CH3)(CF3)2}4]−), and a CuI–S81D coordination polymer with [Cu2(S8)2A22] (7; A2=[Al{OCH(CF3)2}4]−), as a monomeric repeat unit. Complexes4and5are the first example of any metal coordinated to cyclo‐S12and4is the first example of a complex having an element in two allotropic modifications as a ligand.
ChemInform Abstract: Prediction and Characterization of the HMgH···LiX (X: H, OH, F, CCH, CN, and NC) Complexes: A Lithium—Hydride Lithium Bond
Authors: Li Qingzhong , Wang Yifang , Li Wenzuo , Cheng Jianbo , Gong Baoan , Sun Jiazhong
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Noble‐Metal Centered Polycations [Au@Bi10]5+ or [Pd@Bi10]4+ Embedded in Halogenido‐Bismuthate(III)‐Stannate(II) Frameworks.
Authors: Wahl Bernhard , Erbe Manuela , Gerisch Alexander , Kloo Lars , Ruck Michael
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Structure Determination of AgScP2Se6, AgErP2Se6 and AgTmP2Se6.
Authors: Pfitzner Arno , Seidlmayer Stefan
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidative Cleavage of Epoxides Using Aqueous Sodium Paraperiodate.
Authors: Telvekar Vikas N. , Patel Dharmeshkumar J. , Mishra Sanket J.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Free Oxidation of Alcohols with Potassium Persulfate in the Presence of Broensted Acidic Ionic Liquids.
Authors: Chaskar A. C. , Bhandari S. R. , Patil A. B. , Sharma O. P. , Mayeker S.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Homogeneous, Recyclable Rhodium(I) Catalyst for the Hydroarylation of Michael Acceptors.
Authors: Jana Ranjan , Tunge Jon A.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold(I)‐Catalyzed Hydration of Allenes.
Authors: Zhang Zhibin , Lee Seong Du , Fisher Aaron S. , Widenhoefer Ross A.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iodomesitylene‐Catalyzed Oxidative Cleavage of Carbon—Carbon Double and Triple Bonds Using m‐Chloroperbenzoic Acid as a Terminal Oxidant.
Authors: Miyamoto Kazunori , Sei Yoshihisa , Yamaguchi Kentaro , Ochiai Masahito
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Synthesis of γ‐Keto Esters Through Neighboring Carbonyl Group Assisted Regioselective Hydration of 3‐Alkynoates.
Authors: Wang Weibo , Xu Bo , Hammond Gerald B.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Selective Iridium‐Catalyzed Asymmetric Hydrogenation of Trifluoromethyl Olefins: A New Route to Trifluoromethyl‐Bearing Stereocenters.
Authors: Engman Mattias , Cheruku Pradeep , Tolstoy Paivi , Bergquist Jonas , Voelker Sebastian F. , Andersson Pher G.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Trifunctional Organocatalysts for Rate‐Enhanced Aza‐Morita—Baylis—Hillman Reactions at Room Temperature.
Authors: Garnier Jean‐Marc , Anstiss Christopher , Liu Fei
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tandem Metal and Organocatalysis in Sequential Hydroformylation and Enantioselective Mannich Reactions.
Authors: Chercheja Serghei , Rothenbuecher Thomas , Eilbracht Peter
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rationally Designed 4‐Phenoxy‐Substituted Prolinamide Phenols: Organocatalyst for the Direct Aldol Reaction in Water.
Authors: Zhang Shu‐peng , Fu Xiang‐kai , Fu Shao‐dong
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Practical Synthesis of α‐Substituted tert‐Butyl Acrylates from Meldrum′s Acid and Aldehydes.
Authors: Frost Christopher G. , Penrose Stephen D. , Gleave Robert
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidation of γ‐Oxo Sulfides with Chlorine Dioxide.
Authors: Loginova I. V. , Ashikhmina E. V. , Rubtsova S. A. , Krymskaya Yu. V. , Kuchin A. V.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel One‐Pot Procedure for the Synthesis of 1,2‐Diketones.
Authors: Jing Xiaobi , Pan Xin , Li Zhen , Shi Yaocheng , Yan Chaoguo
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Enantioselective Arylation of N‐Tosylarylimines with Arylboronic Acids Using C2‐Symmetric Cationic N‐Heterocyclic Carbene Pd2+ Diaquo Complexes.
Authors: Ma Guang‐Ning , Zhang Tao , Shi Min
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development and Application of a New General Method for the Asymmetric Synthesis of (E)‐(2‐En‐3‐ynyl)‐amines.
Authors: Yin Chao , Hui Xin‐Ping , Xu Peng‐Fei , Niu Liang‐Feng , Chen Yong‐Fei , Wang Binghe
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Facile Access to [60]Fullerene‐Fused δ‐Lactones: Unexpected Reaction Pathway of Benzenediazonium‐2‐carboxylates Controlled by Organic Bases.
Authors: Wang Guan‐Wu , Zhu Bo
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 3‐Indolylpyrroles via Base‐Mediated Cycloaddition of TOSMIC with Activated Indole‐2/3‐vinylenes.
Authors: Balamurugan Ramalingam , Sureshbabu Radhakrishnan , Rajeshwaran Ganesan Gobi , Mohanakrishnan Arasambattu K.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Copper(II)‐Catalyzed Aminooxygenation and Carboamination of N‐Aryl‐2‐allylanilines.
Authors: Sherman Eric S. , Chemler Sherry R.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Regioselective Route to 5‐Substituted Isoxazole‐ and Isoxazoline‐3‐phosphonates.
Authors: Conti Paola , Pinto Andrea , Tamborini Lucia , Dunkel Petra , Gambaro Veniero , Visconti Giacomo L. , De Micheli Carlo
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Sequential Cu(I)/Pd(0)‐Catalyzed Multicomponent Coupling and Annulation Protocol for the Synthesis of Indenoisoquinolines.
Authors: Jayanth Thiruvellore Thatai , Zhang Lei , Johnson Thomas S. , Malinakova Helena C.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Tetra‐ and Penta‐Heterocyclic Compounds Incorporated Isoquinoline Moiety.
Authors: Abdallah Tayseer A. , Hassaneen Hamdi M. , Abdelhadi Hayam A.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of New Nitrogen‐Bridged Heterocycles. Part 65. First Formation of Thiepino[2,3‐b]‐ and Thiepino[3,2‐a]indolizine Derivatives.
Authors: Isawa Hidetoshi , Suga Hiroyuki , Kakehi Akikazu
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of a Novel Polyhydroxylated Salicylic Acid Lactone Framework.
Authors: Rountree J. S. Shane , Murphy Paul V.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Efficient Large‐Scale Synthesis of Boc‐L‐azatyrosine.
Authors: Germain Herve , Harris Craig S. , Renaud Fabrice , Warin Nicolas
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of (‐)‐Monomorine I.
Authors: Bates Roderick W. , Song Ping
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optical and Dynamic Properties of Undoped and Doped Semiconductor Nanostructures
Authors: Zhang Jin Z. , Grant Christian D.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Conjugated Imines and Iminium Salts as Versatile Acceptors of Nucleophiles
Authors: Shimizu Makoto , Hachiya Iwao , Mizota Isao
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Total Synthesis of Biologically Active Natural Products Using Proline‐Catalyzed Asymmetric Aldol Reactions
Authors: Komatsu Yoshiyuki , Ikishima Hideaki , Okuyama Atsushi , Nakamura Mutsumi , Kotsuki Hiyoshizo
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metal Catalyzed Enantioselective [2 + 2 + 2] Cycloadditions for the Synthesis of Axially Chiral Biaryls
Authors: Tanaka Ken
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Insights into Catalytic CO Oxidation on Pt‐Group Metals at Elevated Pressures
Authors: McClure Sean M. , Goodman D. Wayne
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arylphosphinic Acids and Derivatives
Authors: Cristau H.‐J. , Virieux D.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Mechanism and Assembly of the Proteasome
Authors: Marques Antonio J. , Palanimurugan R. , Matias Ana C. , Ramos Paula C. , Dohmen R. Juergen
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Multiple Layers of Ubiquitin‐Dependent Cell Cycle Control
Authors: Wickliffe Katherine , Williamson Adam , Jin Lingyan , Rape Michael
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ubiquitin in NF‐ϰB Signaling
Authors: Chiu Yu‐Hsin , Zhao Meng , Chen Zhijian J.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: ATG Systems from the Protein Structural Point of View
Authors: Noda Nobuo N. , Ohsumi Yoshinori , Inagaki Fuyuhiko
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ribosomal Peptide Natural Products: Bridging the Ribosomal and Nonribosomal Worlds
Authors: McIntosh John A. , Donia Mohamed S. , Schmidt Eric W.
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Protective Effect of Morinda citrifolia on the Ischemic Neuronal Damage
Authors: Harada Shinichi , Hamabe Wakako , Kamiya Kohei , Satake Toshiko , Tokuyama Shogo
Published: June 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Determination of dyeing levelness using surface irregularity function
Authors: Günay Melih
Published: June 2009

An acceptably dyed fabric must be a match to the target and is visually even in appearance, that is, level. Although color difference measurement can objectively determine whether a match has been achieved, levelness is still determined subjectively, leading to inevitable disagreements between dyer and customer. The levelness of a series of dyed fabrics has been objectively evaluated using a surface irregularity function derived from analysis of digital images of the fabrics. The measurements derived correlate more closely to visual assessment than do K/S measurements. © 2009 Wiley Periodicals, Inc. Col Res Appl, 34, 285–290, 2009
Multiangle study on color of textile structures
Authors: Moussa Ali , Dupont Daniel , Steen Daniel , Zeng Xianyi
Published: June 2009

This article studies the influence of the incidence angle of illumination and the textile structure on its coloristic rendering. Three geometric measurements of color (25°a:0°, 45°a:0°, and 75°a:0°) and three different structures (roving, yarn, and woven fabric) were used. The transformations of the reflectance factor spectrum because of the changes of these two parameters were modeled and the evolutions of the colorimetric coordinates associated with these various transformations were thus calculated and analyzed. © 2009 Wiley Periodicals, Inc. Col Res Appl, 34, 274–284, 2009
On the relations between color, gloss, and surface texture in injection‐molded plastics
Authors: Ignell Sofie , Kleist Ulf , Rigdahl Mikael
Published: June 2009

The relation between color and gloss of injection‐molded plastic specimens was evaluated by means of a 45°/0° geometry spectrophotometer and a glossmeter. The specimens were plaques having one smooth, glossy field and one rougher, textured region made of two different polymeric materials (acrylonitrile‐butadiene‐styrene and polypropylene) in a range of colors. A significant influence of the lightness L* of the specimens on the measured gloss of the textured field, with a low gloss appearance, was found. This can probably be attributed to a contribution from bulk scattering, which is linked to the reflectance from within the specimen. The influence of texture on the measured color of the plaques was assessed by evaluating the color difference between the smooth field and the more textured area on the specimens. When the surface was textured, the color changed; in general it became lighter and less saturated. The magnitude of the change depended on the color of the material. The darker the material was, the larger was the increase in lightness L* as the surface became rougher. The shift in chroma C* was determined not only by the saturation but also by the lightness of the specimens. Darker specimens exhibited a larger decrease in chroma when the surface was textured. The change in the measured color caused by increasing the surface roughness could be predicted in a satisfactory manner using a model developed for xerographic printing paper. © 2009 Wiley Periodicals, Inc. Col Res Appl, 34, 291–298, 2009
Correlated Movement and Bending of Nucleic Acid Structures Visualized by Multicolor Single‐Molecule Spectroscopy
Authors: Person Britta , Stein Ingo H. , Steinhauer Christian , Vogelsang Jan , Tinnefeld Philip
Published: June 2009

At the end of the rainbow…︁ The structure and dynamics of three‐ and four‐ way DNA junctions are studied using triple alternating laser excitation. Steroid binding distorts the structure of three‐way junctions with correlated bending of all branches towards a steeper pyramid (see picture). In four‐way junctions, the dynamics of three distances are visualized simultaneously.

magnified image
A flow cytometric assay for the study of E3 ubiquitin ligase activity
Authors: Hilliard Joshua G. , Cooper Anne L. , Slusser Joyce G. , Davido David J.
Published: June 2009

Current methods for monitoring E3 ubiquitin ligase activity in cell culture or in vivo are limited. As a result, the degradation of cellular targets by many E3 ubiquitin ligases in live cells has not yet been examined. For this study, a target of an E3 ubiquitin ligase was expressed as a fluorescently labeled protein in cell culture. If the E3 ubiquitin ligase mediates the degradation of a target protein in cell culture, it is expected that the target will show a reduced fluorescence signal by FCM analysis. We initially used the E3 ubiquitin ligase, herpes simplex virus type 1 (HSV‐1) infected cell protein 0 (ICP0) and one of its targets, promyelocytic leukemia (PML) protein, to determine the feasibility of our approach. Cells expressing a PML‐GFP fusion protein were selected by cell sorting and infected with an adenoviral vector expressing ICP0. In contrast to mock‐infected cells, only PML‐GFP‐expressing cells infected with the ICP0 adenoviral vector led to a significant decrease in the fluorescence signal of PML‐GFP when examined by fluorescence microscopy and FCM analysis. Our results suggest that it is possible to examine the live activity of an E3 ubiquitin ligase (via one of its targets) in cell culture by FCM analysis. © 2009 International Society for Advancement of Cytometry
Enrichment and expansion of cells using antibody‐coated micropallet arrays
Authors: Shadpour Hamed , Sims Christopher E. , Allbritton Nancy L.
Published: June 2009

Positive selection, sorting, and collection of single cells from within a heterogeneous population are required for many biological studies. We recently demonstrated a miniaturized cell array for this purpose; however, on‐chip pre‐enrichment and isolation of specific target cells would provide significant value for cell isolation. In the current work, mixed cell samples of fewer than 30,000 cells were used for panning by means of on‐array antibody‐capture to pre‐enrich the target population. The cell surface receptors FcεR1, c‐Kit, and ErbB2 were used for positive selection of RBL, RBL, and SK‐BR‐3 cells, respectively, from the mixed population. The capture efficiency, selectivity, and enrichment for the target cells were calculated and compared with fibronectin‐coated controls. As expected, the capture efficiency depended on the frequency of the target cell in the mixed population over the range of 0.3–33%. For a frequency of 5% target cells, the capture efficiency was 39%–53% for the three conditions, while the selectivity varied between 78% and 98% with 16–20‐fold enrichment. Furthermore, single‐cell cloning studies demonstrated a high cloning efficiency of target cells selectively isolated from the array. Antibody‐based pre‐enrichment in combination with micropallet‐based cell selection will be a valuable tool for isolation and expansion of rare cells from small heterogeneous populations. © 2009 International Society for Advancement of Cytometry
The effect of amygdala kindling on hippocampal neurogenesis coincides with decreased reelin and DISC1 expression in the adult dentate gyrus
Authors: Fournier N.M. , Andersen D.R. , Botterill J.J. , Sterner E.Y. , Lussier A.L. , Caruncho H.J. , Kalynchuk L.E.
Published: June 2009

Temporal lobe seizures can induce the proliferation and abnormal migration of newly generated dentate granule cells, but little is known about the molecular mechanisms that govern these pathological events. Reelin and DISC1 (disrupted‐in‐schizophrenia 1) are proteins that play a regulatory role in the maturation and integration of new neurons in the developing and adult brain. In this study, we examined whether amygdala kindling results in aberrant neurogenesis and altered expression of reelin and DISC1 in the adult dentate gyrus. Using doublecortin immunohistochemistry, we found that short‐term kindling (i.e., 30 electrical stimulations) significantly increased the number of immature neurons in the dentate subgranular zone (SGZ), whereas long‐term kindling (i.e., 99 electrical stimulations) did not. However, doublecortin‐labeled neurons in long‐term kindled rats showed greater dendritic complexity than they did in short‐term kindled or control rats. We also found that long‐term kindling decreased the number of reelin‐positive cells and decreased DISC1 expression in the dentate granule cell layer and subgranular zone. Interestingly, kindling‐induced changes in reelin and DISC1 expression coincided with the appearance of ectopically located Prox1‐labeled granule cells in the hilus. These effects occurred independently of alterations in granule cell layer length, dentate volume, or the number of hilar neurons. Taken together, these findings suggest a novel role for DISC1 in the pathophysiology of temporal lobe epilepsy and further suggest that changes in reelin and DISC1 expression may contribute to aberrant neurogenesis in the kindling model. © 2009 Wiley‐Liss, Inc.