bluuebunny/crossref_metadata_2025 huggingface dataset:
Worldwide Age at Onset of Female Breast Cancer: A 25-Year Population-Based Cancer Registry Study
Authors: Bidoli Ettore , Virdone Saverio , Hamdi-Cherif Mokhtar , Toffolutti Federica , Taborelli Martina , Panato Chiara , Serraino Diego
Published: October 2019

A higher frequency of early onset female breast cancers (BC) has been observed in low/middle income countries than in high income countries. We quantified the role of population ageing to this pattern using data from all population-based cancer registries (CRs) worldwide. Patients’ median age at BC onset and that of the general population were extracted for CRs listed in volumes VI (1983–1987 years) through XI (2008–2012 years) of Cancer Incidence in Five Continents. Their association was assessed at cross-sectional level by linear regression model and longitudinally considering 25-year ageing of the population in long-standing CRs listed at the beginning and at the end of the study. During 2008–2012, each one-year increase of population ageing was associated with a nearly ½ year increase of age at BC diagnosis. Population demographics explained forty-two percent of the age variance for BC. In 1983–1987, long-standing CRs with a median age at BC below age 61.8 years showed an increase of age at BC after 25-years. Worldwide, age at BC diagnosis essentially reflected the median age of the population. Changes in BC detection methodology likely lessened this association. Nevertheless, the elevated absolute number of BCs in young populations deserves strategies of BC prevention.
Inactivated alpha toxin from Clostridium novyi type B in nano-emulsion protect partially protects Swiss mice from lethal alpha toxin challenge
Authors: Felix Mellanie Karoline C. , Deusdará Tullio T. , Santos Lucas Samuel S. , Aguiar Raimundo Wagner S. , Corrêa Roberto Franco T. , Brandi Igor V. , Sobrinho Eliane M. , Ribeiro Bergmann M. , Mariúba Luis André M. , Nogueira Paulo A. , Costa Kattyanne S. , Viana Kelvinson F. , Cangussu Alex Sander R.
Published: October 2019

Nano-emulsions are promising carriers for antigen delivery. Here, we evaluated the efficacy of a water-oil nano-emulsion containing concentrated, inactivated Clostridium novyi (C. novyi) type B supernatant culture (nano-iCnB) in protecting Swiss mice against a lethal dose of alpha toxin concentrated extract. Proteins were confirmed in the nano-iCnB and their stabilities were determined according physical parameters such as Zeta Potential (ZP). Biochemical, hematological parameters and morphological appearance of liver, spleen and thigh muscle alterations were examined to determine the safety of the compound. Partial protection against lethal doses was achieved in immunized mice despite low IgG titers. These data suggest that our nano-emulsion is a simple and efficient method of promoting antigen delivery for toxin-related diseases.
Quantitative analysis of Gria1, Gria2, Dlg1 and Dlg4 expression levels in hippocampus following forced swim stress in mice
Authors: Freudenberg Florian
Published: October 2019

AMPA receptors and interacting proteins are importantly involved in mediating stress-dependent plasticity. Previously we reported that GluA1-containing AMPA receptors and their interaction with PDZ-proteins are required for the experience-dependent expression of behavioral despair in the forced swim test. However, it is unclear if the expression of GluA1-containing AMPA receptors is affected by this type of behavior. Here we investigated in wild type mice, whether hippocampal gene or protein levels of GluA1 or associated PDZ proteins is altered following forced swim stress. We show that expression of Dlg4 (the gene coding for PSD-95) was strongly reduced after two days of forced swimming. In contrast, levels of Dlg1, Gria1, and Gria2 (coding for SAP97, GluA1, and GluA2 respectively) were not affected after one or two days of forced swimming. The changes in gene expression largely did not translate to the protein level. These findings indicate a limited acute effect of forced swim stress on the expression of the investigated targets and suggest that the acute involvement of GluA1-containing AMPA receptors tor forced swim behavior is a result of non-genomic mechanisms.
Individual differences in the attentional modulation of the human auditory brainstem response to speech inform on speech-in-noise deficits
Authors: Saiz-Alía Marina , Forte Antonio Elia , Reichenbach Tobias
Published: October 2019

People with normal hearing thresholds can nonetheless have difficulty with understanding speech in noisy backgrounds. The origins of such supra-threshold hearing deficits remain largely unclear. Previously we showed that the auditory brainstem response to running speech is modulated by selective attention, evidencing a subcortical mechanism that contributes to speech-in-noise comprehension. We observed, however, significant variation in the magnitude of the brainstem’s attentional modulation between the different volunteers. Here we show that this variability relates to the ability of the subjects to understand speech in background noise. In particular, we assessed 43 young human volunteers with normal hearing thresholds for their speech-in-noise comprehension. We also recorded their auditory brainstem responses to running speech when selectively attending to one of two competing voices. To control for potential peripheral hearing deficits, and in particular for cochlear synaptopathy, we further assessed noise exposure, the temporal sensitivity threshold, the middle-ear muscle reflex, and the auditory-brainstem response to clicks in various levels of background noise. These tests did not show evidence for cochlear synaptopathy amongst the volunteers. Furthermore, we found that only the attentional modulation of the brainstem response to speech was significantly related to speech-in-noise comprehension. Our results therefore evidence an impact of top-down modulation of brainstem activity on the variability in speech-in-noise comprehension amongst the subjects.
Resource use efficiency of indoor lettuce (Lactuca sativa L.) cultivation as affected by red:blue ratio provided by LED lighting
Authors: Pennisi Giuseppina , Orsini Francesco , Blasioli Sonia , Cellini Antonio , Crepaldi Andrea , Braschi Ilaria , Spinelli Francesco , Nicola Silvana , Fernandez Juan A. , Stanghellini Cecilia , Gianquinto Giorgio , Marcelis Leo F. M.
Published: October 2019

LED lighting in indoor farming systems allows to modulate the spectrum to fit plant needs. Red (R) and blue (B) lights are often used, being highly active for photosynthesis. The effect of R and B spectral components on lettuce plant physiology and biochemistry and resource use efficiency were studied. Five red:blue (RB) ratios (0.5-1-2-3-4) supplied by LED and a fluorescent control (RB = 1) were tested in six experiments in controlled conditions (PPFD = 215 μmol m−2 s−1, daylength 16 h). LED lighting increased yield (1.6 folds) and energy use efficiency (2.8 folds) as compared with fluorescent lamps. Adoption of RB = 3 maximised yield (by 2 folds as compared with RB = 0.5), also increasing leaf chlorophyll and flavonoids concentrations and the uptake of nitrogen, phosphorus, potassium and magnesium. As the red portion of the spectrum increased, photosystem II quantum efficiency decreased but transpiration decreased more rapidly, resulting in increased water use efficiency up to RB = 3 (75 g FW L−1 H2O). The transpiration decrease was accompanied by lower stomatal conductance, which was associated to lower stomatal density, despite an increased stomatal size. Both energy and land surface use efficiency were highest at RB ≥ 3. We hereby suggest a RB ratio of 3 for sustainable indoor lettuce cultivation.
Zero electrical power pump for portable high-performance liquid chromatography
Authors: Chatzimichail Stelios , Casey Duncan , Salehi-Reyhani Ali
Published: October 2019

A major trend in analytical chemistry is the miniaturization of laboratory instrumentation. We present a portable high-performance liquid chromatography system for field based chemical analyses.
Applications of 1,3,5-trimethoxybenzene as a derivatizing agent for quantifying free chlorine, free bromine, bromamines, and bromide in aqueous systems
Authors: Dias Ryan P. , Schammel Marella H. , Reber Keith P. , Sivey John D.
Published: October 2019

Free chlorine and free bromine (e.g., HOCl and HOBr) are employed as disinfectants in a variety of aqueous systems, including drinking water, wastewater, ballast water, recreational waters, and cleaning products.
Simultaneous analysis of phosphopeptides and intact glycopeptides from secretome with mode switchable solid phase extraction
Authors: Chen Rui , Williamson Sam , Fulton Kelly M. , Twine Susan M. , Li Jianjun
Published: October 2019

We present a novel method named mode switchable solid phase extraction (MS-SPE) for simultaneous enrichment of phosphopeptides and glycopeptides from the digest of cancer cell secretome.
Boronate affinity mesoporous silica nanoparticle based selective enrichment for highly efficient analysis of ginsenosides
Authors: Chen Yang , Zhao Weiman , Qing Chen , Wu Wei , Chen Shaoyong , Bie Zijun
Published: October 2019

Panax ginseng has been one of the most famous traditional herbs in eastern Asia as well as North America for thousands of years.
High performance photoanodic catalyst prepared from an active organic photovoltaic cell – high potential gain from visible light
Authors: Nagai Keiji , Kuwabara Takayuki , Ahmad Mohd Fairus , Nakano Masahiro , Karakawa Makoto , Taima Tetsuya , Takahashi Kohshin
Published: October 2019

Photoelectrochemical oxidation of thiols was enhanced with a threshold potential of −0.35 V vs. Ag/AgCl by a ZnPc/PCBM:P3HT/ZnO electode, which was prepared by removing the PEDOT:PSS/Au electrode of an inverted OPV device and coating it with ZnPc.
Rhodium catalysed synthesis of seleno-ketals via carbene transfer reactions of diazoesters
Authors: Jana Sripati , Aseeva Polina , Koenigs Rene M.
Published: October 2019

Seleno-ketals can be accessed via rhodium catalysed carbene transfer reactions in water as solvent.
The effect of ionic strength and phosphate ions on the construction of redox polyelectrolyte–enzyme self-assemblies
Authors: Zappi Daniele , Coria-Oriundo Lucy L. , Piccinini Esteban , Gramajo Marcos , von Bilderling Catalina , Pietrasanta Lía I. , Azzaroni Omar , Battaglini Fernando
Published: October 2019

The type and concentration of ions present in a solution containing an electroactive polyelectrolyte shape its configuration, adsorption, and electrochemical response.
Alloy, Janus and core–shell nanoparticles: numerical modeling of their nucleation and growth in physical synthesis
Authors: Förster Georg Daniel , Benoit Magali , Lam Julien
Published: October 2019

Growth mechanisms occurring in physical synthesis are studied in the case of alloy, Janus and core–shell nanoparticles. We particularly investigated how the structure of the obtained nanoparticles can be influenced by the cooling rate.
The 3s versus 3p Rydberg state photodissociation dynamics of the ethyl radical
Authors: Marggi Poullain Sonia , Chicharro David V. , Zanchet Alexandre , Rubio-Lago Luis , García-Vela Alberto , Bañares Luis
Published: October 2019

Photodissociation dynamics of the ethyl radical from the 3s vs. 3p Rydberg states studied by velocity map imaging and ab initio electronic structure calculations.
Strategic planning of proteins in ionic liquids: future solvents for the enhanced stability of proteins against multiple stresses
Authors: Kumar Awanish , Bhakuni Kavya , Venkatesu Pannuru
Published: October 2019

Ionic liquids (ILs) represent as solvents or co-solvents for protein stabilization and refolding. Thus, ILs are replacement to toxic organic solvents in chemical, biotechnology and biomedical applications.
Fluctuation–dissipation analysis of nonequilibrium thermal transport at the hydrate dissociation interface
Authors: Li Jia , Wang Zhao-Liang
Published: October 2019

Thermal fluctuation–dissipation at the interface is justified in the nonequilibrium process of hydrate dissociation in terms of heat flux.
Polyoxometalates as alternative Mo precursors for methane dehydroaromatization on Mo/ZSM-5 and Mo/MCM-22 catalysts
Authors: Julian Ignacio , Hueso José L. , Lara Nidya , Solé-Daurá Albert , Poblet Josep M. , Mitchell Scott G. , Mallada Reyes , Santamaría Jesús
Published: October 2019

Catalytic stability and overall performance enhancement for the methane dehydroaromatization process using a combination of hexamolybdate species as Mo precursors and MCM-22 as catalysts support.
ZnO nanorods modified with noble metal-free Co3O4 nanoparticles as a photocatalyst for efficient ethylene degradation under light irradiation
Authors: Cui Zihao , Liu Xiaolei , Liang Xizhuang , Wang Peng , Zhang Qianqian , Wang Zeyan , Zheng Zhaoke , Liu Yuanyuan , Dai Ying , Huang Baibiao
Published: October 2019

ZnO modified with noble metal-free Co3O4 nanoparticles was prepared by a simple method and showed good stability and high efficiency for photo-oxidizing ethylene.
Theoretical study of aromatic hydroxylation of the [Cu2(H-XYL)O2]2+ complex mediated by a side-on peroxo dicopper core and Cu-ligand effects
Authors: Liu Yan Fang , Shen Junliang , Chen Shi-Lu , Qiao Weiye , Zhou Suqin , Hong Kun
Published: October 2019

The newly designed more efficient catalyst D1 and the aromatic hydroxylation mechanism of the [Cu2(H-XYL)O2]2+ complex mediated by a peroxo dicopper core.
Flexible and self-standing nickel ferrite–PVDF-TrFE cast films: promising candidates for high-end magnetoelectric applications
Authors: Mayeen Anshida , M. S. Kala , M. S. Jayalakshmy , Thomas Sabu , Philip Jacob , Rouxel Didier , Bhowmik R. N. , Kalarikkal Nandakumar
Published: October 2019

Polymer-based magnetoelectrics are identified as a newly emerging area of research due to their profound potential applications centered on spintronic technology.
Fine-tuning the type of equatorial donor atom in pentagonal bipyramidal Dy(iii) complexes to enhance single-molecule magnet properties
Authors: Wu Haipeng , Li Min , Yin Bing , Xia Zhengqiang , Ke Hongshan , Wei Qing , Xie Gang , Chen Sanping , Gao Shengli
Published: October 2019

Upon fine-tuning an equatorial donor, the electronic effect is implemented to significantly enhance magnetic anisotropy in pentagonal bipyramidal DyIII complexes.
Catalytic epoxidation of olefins in liquid phase over manganese based magnetic nanoparticles
Authors: Yan Wenjuan , Wang Jinyao , Ding Jie , Sun Puhua , Zhang Shuxia , Shen Jian , Jin Xin
Published: October 2019

Olefin epoxidation over Mn supported on magnetic nanoparticles.
Lithium cations in a self-assembled electrostatic nanocapsule
Authors: Mayans Júlia , Font-Bardia Mercé , Escuer Albert
Published: October 2019

A self-assembled {Ni12Li2} nanometric capsule with endo- and exo-guests linked to selective hydrophilic/hydrophobic binding sites of NiII6 rings was achieved by using (Bu4N)N3 instead of sodium azide to selectively introduce the Li+ cations.
Experimental and theoretical insights into the synthesis of α-aminoalkyl naphthol derivatives catalyzed by a manganese complex immobilized on multi-walled carbon nanotubes
Authors: Rakhtshah Jamshid , Yaghoobi Fereshteh
Published: October 2019

The full details of the synthesis of α-aminoalkyl naphthol derivatives promoted by a manganese complex immobilized on multi-walled carbon nanotubes (CNTs@Mn-bpy) are described, with a particular focus on theoretical mechanistic aspects.
PIDA-mediated α-C–H functionalization of enaminones: the synthesis of thiocyano enaminones and chromones in water
Authors: Yang Zan , Hu Liping , Cao Ting , An Li , Li Lijun , Yang Tao , Zhou Congshan
Published: October 2019

Herein, an efficient, metal-free process for the α-C–H thiocyanation of enaminones was developed using PhI(OAc)2 as an oxidant at room temperature in an aqueous medium.
A carbon dot based theranostic platform for dual-modal imaging and free radical scavenging
Authors: Lin Jin-Sheng , Tsai Yi-Wen , Dehvari Khalilalrahman , Huang Chih-Ching , Chang Jia-Yaw
Published: October 2019

Red emitting carbon dots with phosphorus and manganese dopants were explored for synergistic in vitro fluorescence/MR imaging and cytoprotective effects.
Ultrafine PtCuRh nanowire catalysts with alleviated poisoning effect for efficient ethanol oxidation
Authors: Chen Chunyan , Xu Hui , Shang Hongyuan , Jin Liujun , Song Tongxin , Wang Cheng , Gao Fei , Zhang Yangping , Du Yukou
Published: October 2019

A robust and universal seed-mediated growth method has been developed for making a series of ultrafine PtCuM (M = Rh, Pd, Ir) alloy nanowires, which show greatly improved electrocatalytic performance for ethanol oxidation reaction.
Shortwave infrared fluorescence in vivo imaging of nerves for minimizing the risk of intraoperative nerve injury
Authors: Xu Heng , Chen Jun , Feng Zhujun , Fu Kan , Qiao Yusen , Zhang Zheng , Wang Wenjin , Wang Yueming , Zhang Jian , Perdanasari Aurelia Trisliana , Hanasono Matthew M. , Levin L. Scott , Yang Xing , Hao Yuefeng , Li Yunxia , Wo Yan , Zhang Yixin
Published: October 2019

A novel nerve specific imaging agent based on SWIR QD-based in vivo imaging can markedly minimize the risk of iatrogenic nerve injuries during surgeries by providing real-time and long-time SWIR images of peripheral nerves in specific.
The Mukaiyama type aldol reaction for the synthesis of trans-2,6-disubstituted tetrahydropyrans: synthesis of diospongin A and B
Authors: Bharath Yada , Choudhury Utkal Mani , Sadhana N. , Mohapatra Debendra K.
Published: October 2019

The synthesis of 2,6-trans-disubstituted tetrahydropyrans following the Mukaiyama type aldol reaction through C–C bond formation demonstrates the practicality of this protocol in the total synthesis of diospongin A and B.
Synthesis of fused imidazo[1,2-a]pyridines derivatives through cascade C(sp2)–H functionalizations
Authors: Li Bin , Shen Nana , Zhang Xinying , Fan Xuesen
Published: October 2019

An efficient and convenient synthesis of fused imidazo[1,2-a]pyridine derivatives from the cascade reactions of 2-arylimidazo[1,2-a]pyridines with a-diazo carbonyl compounds via Rh(iii)-catalyzed C(sp2)–H functionalization/annulation is presented.
Recent trends and applications of the Cadiot–Chodkiewicz reaction
Authors: Radhika Sankaran , Harry Nissy Ann , Neetha Mohan , Anilkumar Gopinathan
Published: October 2019

The Cadiot–Chodkiewicz reaction offers an elegant strategy for the formation of 1,3-diynes via Cu-catalyzed cross-coupling of alkynyl halides with terminal alkynes in the presence of an amine.
Theoretical predictions for low-temperature phases, softening of phonons and elastic stiffnesses, and electronic properties of sodium peroxide under high pressure
Authors: Jimlim Pornmongkol , Tsuppayakorn-aek Prutthipong , Pakornchote Teerachote , Ektarawong Annop , Pinsook Udomsilp , Bovornratanaraks Thiti
Published: October 2019

High-pressure phase stabilities up to 600 K and the related properties of Na2O2under pressures up to 300 GPa were investigated using first-principles calculations and the quasi-harmonic approximation.
Synthesis of silver particles stabilized by a bifunctional SiHx–NHy–PMHS oligomer as recyclable nanocatalysts for the catalytic reduction of 4-nitrophenol
Authors: Wang Zhen , Yao Shun , Pan Shaofei , Su Jian , Fang Changqing , Hou Xianliang , Zhan Mei
Published: October 2019

A novel strategy using bifunctional SiHx–NHy–PMHS without using strong stabilizers was applied to synthesize Ag NPs of around 2 nm size.
Characterization of nZVI nanoparticles functionalized by EDTA and dipicolinic acid: a comparative study of metal ion removal from aqueous solutions
Authors: Rončević Sanda , Nemet Ivan , Ferri Tea Zubin , Matković-Čalogović Dubravka
Published: October 2019

Surface modification of nZVI particles by EDTA and PDCA leads to the formation of magnetite and feroxyhyte shell. PDCA capping caused the elongation of spheres into ellipsoids. Metals adsorption was more efficient on smaller ellipsoidal particles.
The synthesis of nanofiber membranes from acrylonitrile butadiene styrene (ABS) waste using electrospinning for use as air filtration media
Authors: Zulfi Akmal , Hapidin Dian Ahmad , Munir Muhammad Miftahul , Iskandar Ferry , Khairurrijal Khairurrijal
Published: October 2019

Acrylonitrile butadiene styrene (ABS) waste has been successfully recycled into nanofiber membranes by an electrospinning method for air filter applications.
Quantum chemical elucidation of the turn-on luminescence mechanism in two new Schiff bases as selective chemosensors of Zn2+: synthesis, theory and bioimaging applications
Authors: Berrones-Reyes Jessica C. , Muñoz-Flores Blanca M. , Cantón-Diáz Arelly M. , Treto-Suárez Manuel A. , Páez-Hernández Dayan , Schott Eduardo , Zarate Ximena , Jiménez-Pérez Víctor M.
Published: October 2019

Two new selective zinc sensors (S,E)-11-amino-8-((2,4-di-tert-butyl-1-hydroxybenzylidene)amino)-11-oxopentanoic acid (A) and (S,E)-11-amino-8-((8-hydroxybenzylidene)amino)-11-oxopentanoic acid (B) based on a Schiff base and an amino acid are reported.
In vitrostudy of chitosan-based multi-responsive hydrogels as drug release vehicles: a preclinical study
Authors: Gull Nafisa , Khan Shahzad Maqsood , Zahid Butt Muhammad Taqi , Khalid Syed , Shafiq Muhammad , Islam Atif , Asim Sumreen , Hafeez Sadaf , Khan Rafi Ullah
Published: October 2019

Pictorial diagram of multi-responsive hydrogels for controlled drug release system.
Comparative study of mesoporous NixMn6−xCe4 composite oxides for NO catalytic oxidation
Authors: Weiman Li , Haidi Liu , Min Zhang , Yunfa Chen
Published: October 2019

In this work, a series of mesoporous NixMn6−xCe ternary oxides were prepared to investigate their NO catalytic oxidation ability.
Rhodamine B derivative-modified up-conversion nanoparticle probes based on fluorescence resonance energy transfer (FRET) for the solid-based detection of copper ions
Authors: Liu Xiaoyan , Ding Nan , Wang Jun , Chen Honglan , Chen Xinwei , Wang Zhidong , Peng Xincun
Published: October 2019

A novel solid-based up-conversion FRET sensor is convenient for the direct detection of Cu2+ based on color change and emission spectra.
Fluorescence-based ion sensing in lipid membranes: a simple method of sensing in aqueous medium with enhanced efficiency
Authors: Barla Leena Sushmita , Pattnaik Gourab Prasad , Meher Geetanjali , Padhan Subrata Kumar , Sahu Satya Narayan , Chakraborty Hirak
Published: October 2019

Our strategy provides an opportunity to tune the hydrophobic molecular sensors to sense ions in aqueous solutions with enhanced efficiency by incorporating them in lipid membranes.
Poly(vinylbenzyl chloride-co-divinyl benzene) polyHIPE monolith-supported o-hydroxynaphthaldehyde propylenediamine Schiff base ligand complex of copper(ii) ions as a catalyst for the epoxidation of cyclohexene
Authors: Moghe Keerti , Sutar A. K. , Kang I. K. , Gupta K. C.
Published: October 2019

High internal phase emulsion of vinyl benzene and divinyl benzene in aqueous calcium chloride produced porous monoliths,which improved the activity of supported HNPn-Cu catalyst in selective oxidation of cyclohexene in presence hydrogen peroxide.
Probing the properties of lattice vibrations and surface electronic states in magnetic semiconductor CrPS4
Authors: Wu Hongbiao , Chen Haiping
Published: October 2019

Searching for multifunctional materials with magnetism and semiconductivity is one of the goals of research into two-dimensional (2D) systems.
Effects of nanobubble water on the growth ofLactobacillus acidophilus1028 and its lactic acid production
Authors: Guo Zitao , Wang Xuezhi , Wang Hanxiao , Hu Bo , Lei Zhongfang , Kobayashi Motoyoshi , Adachi Yasuhisa , Shimizu Kazuya , Zhang Zhenya
Published: October 2019

Nanobubbles (NBs) in the culture medium may offer a new way of accelerating bacterial growth in the lag and logarithmic phases.
Preparation of SiO2@TiO2:Eu3+@TiO2 core double-shell microspheres for photodegradation of polyacrylamide
Authors: Zou Haoyang , Wang Lan , Tao Huaizhi , Liu Yi , Chang Meiqi , Yao Shiyu
Published: October 2019

SiO2@TiO2:Eu3+@TiO2 core double-shell microspheres with an ideal photocatalytic activity are designed and prepared for photodegradation of HPAM.
A biobased Schiff base from protocatechualdehyde and its application in flame-retardant, low-smoke epoxy resin systems
Authors: Xie Weiqi , Huang Shiwen , Liu Shumei , Zhao Jianqing
Published: October 2019

A novel bio-based Schiff base compound PH-ODA was successfully synthesized and acted as a carbonization agent of IFRs for fire-safe epoxy resins.
Development of active and intelligent films based on cassava starch and Chinese bayberry (Myrica rubra Sieb. et Zucc.) anthocyanins
Authors: Yun Dawei , Cai Huahao , Liu Yunpeng , Xiao Lixia , Song Jiangfeng , Liu Jun
Published: October 2019

In this study, anthocyanin-rich Chinese bayberry extract (BBE) was added into cassava starch to develop food packaging films with antioxidant and pH-sensitive properties.
On-the-fly catalytic degradation of organic pollutants using magneto-photoresponsive bacteria-templated microcleaners
Authors: Mushtaq Fajer , Chen Xiangzhong , Staufert Silvan , Torlakcik Harun , Wang Xiaopu , Hoop Marcus , Gerber Ann , Li Xinghao , Cai Jun , Nelson Bradley J. , Pané Salvador
Published: October 2019

Visible-light active photocatalysis under continuous magnetic actuation.
Robust redox-reversible perovskite type steam electrolyser electrode decorated with in situ exsolved metallic nanoparticles
Authors: Liu Tong , Zhao Yiqian , Zhang Xiaoyu , Zhang Hong , Jiang Guang , Zhao Wen , Guo Jiayi , Chen Fanglin , Yan Mufu , Zhang Yanxiang , Wang Yao
Published: October 2019

Herein, the redox-reversible stability of a perovskite type SFMNi cathode decorated with in situ exsolved Ni–Fe alloy nanoparticles is investigated using experimental results and explained by the exsolution–redissolution model.
Silicon: toward eco-friendly reduction techniques for lithium-ion battery applications
Authors: Zhu Guanjia , Luo Wei , Wang Lianjun , Jiang Wan , Yang Jianping
Published: October 2019

This review summarizes the progress on four eco-friendly reduction techniques, including the detailed mechanism, reaction conditions, product morphology and electrochemical performance.
Efficient and robust lithium metal electrodes enabled by synergistic surface activation–passivation of copper frameworks
Authors: Yun Jonghyeok , Won Eun-Seo , Shin Hyun-Seop , Jung Kyu-Nam , Lee Jong-Won
Published: October 2019

The synergistic surface tailoring of three-dimensional Cu frameworks achieved via Ag-induced activation and Al2O3-induced passivation leads to a significant improvement in the Li plating–stripping efficiency and cycling performance.
Layer-by-layer stacked nanohybrids of N,S-co-doped carbon film modified atomic MoS2 nanosheets for advanced sodium dual-ion batteries
Authors: Liu YangJie , Hu Xiang , Zhong Guobao , Chen Junxiang , Zhan Hongbing , Wen Zhenhai
Published: October 2019

The hierarchical coral-like MoS2/carbon nanohybrids constructed by layer-by-layer stacked atomic MoS2 nanosheets modified by nitrogen and sulfur co-doped carbon film exhibited highly desired Na+ storage capability as anode for sodium dual-ion batteries.
Anionic P-substitution toward ternary Ni–S–P nanoparticles immobilized graphene with ultrahigh rate and long cycle life for hybrid supercapacitors
Authors: Jiang Bing , Ban Xiaohan , Wang Qian , Cheng Kui , Zhu Kai , Ye Ke , Wang Guiling , Cao Dianxue , Yan Jun
Published: October 2019

Ternary Ni–S–P nanoparticles on graphene have been prepared through anionic substitution for supercapacitors for the first time.
Inflammation-responsive functional Ru nanoparticles combining a tumor-associated macrophage repolarization strategy with phototherapy for colorectal cancer therapy
Authors: Liu Yanan , Wen Yayu , Chen Xu , Zhu Xufeng , Yu Qianqian , Gong Youcong , Yuan Guanglong , Liu Jie , Qin Xiuying
Published: October 2019

Schematic illustration for (A) synthetic procedure of Ru@ICG–BLZ NPs nanoparticles and (B) mechanism of Ru@ICG–BLZ NPs in a combined phototherapy and TAM-switching treatment strategy.
Boosting the photocatalytic activity of graphite carbon nitride by designing novel MoS2–transition metal heterojunction cocatalysts
Authors: Li Kui , Lin Ye-Zhan , Zhang Yu , Xu Mei-Ling , Liu Ling-Wang , Liu Fu-Tian
Published: October 2019

MoS2–transition metal heterojunctions were adopted as cocatalysts on the earth-abundant g-C3N4 and displayed a synergistic effect on improving the photocatalytic performance.
Second-order nonlinear optical properties of [60]fullerene-fused dihydrocarboline derivates: a theoretical study on switch effect
Authors: Ma Nana , Lv Mingyue , Liu Tongxin , Song Mengxiao , Liu Yan , Zhang Guisheng
Published: October 2019

The theoretical calculations show that [60]fullerene-fused dihydrocarboline derivatives exhibit significant first hyperpolarizability contrasts induced by their electrochemical feature.
Effects of intramolecular hydrogen bonding on the conformation and luminescence properties of dibenzoylpyridine-based thermally activated delayed fluorescence materials
Authors: Pandidurai Jayabalan , Jayakumar Jayachandran , Senthilkumar Natarajan , Cheng Chien-Hong
Published: October 2019

The crystal structures show a U shape for 26DAcBPy and 26DPXZBPy and a linear chain conformation for 25DAcBPy; for the first time, we reveal that the conformations are the result of intramolecular hydrogen bonding of these molecules.
Etching- and intermediate-free graphene dry transfer onto polymeric thin films with high piezoresistive gauge factors
Authors: Li Runlai , Zhang Qinghua , Zhao Eric , Li Jin , Gu Qiao , Gao Ping
Published: October 2019

Graphene was transferred onto polymers utilizing wdW interaction by exfoliating copper off, with no intermediate or etching needed.
Optical validation and characterization of Planck PSZ2 sources at the Canary Islands observatories
Authors: Aguado-Barahona A. , Barrena R. , Streblyanska A. , Ferragamo A. , Rubiño-Martín J. A. , Tramonte D. , Lietzen H.
Published: October 2019

Context. The second legacy catalog of Planck Sunyaev–Zeldovich (SZ) sources, hereafter PSZ2, provides the largest galaxy cluster sample selected by means of the SZ signature of the clusters in a full sky survey. In order to fully characterize this PSZ2 sample for cosmological studies, all the members should be validated and the physical properties of the clusters, including mass and redshift, should be derived. However, at the time of its publication, roughly 21% of the 1653 PSZ2 members had no known counterpart at other wavelengths.

Aims. Here, we present the second and last year of observations of our optical follow-up program 128-MULTIPLE-16/15B (hereafter LP15), which has been developed with the aim of validating all the unidentified PSZ2 sources in the northern sky with declinations higher than −15° that have no correspondence in the first Planck catalog PSZ1. The description of the program and the first year of observations have been presented previously.

Methods. The LP15 program was awarded 44 observing nights that were spread over two years with the Isaac Newton Telescope (INT), the Telescopio Nazionale Galileo (TNG), and the Gran Telescopio Canarias (GTC), all at Roque de los Muchachos Observatory (La Palma). Following the same method as described previously, we performed deep optical imaging for more than 200 sources with the INT and spectroscopy for almost 100 sources with the TNG and GTC at the end of the LP15 program. We adopted robust confirmation criteria based on velocity dispersion and richness estimates for the final classification of the new galaxy clusters as the optical counterparts of the PSZ2 detections.

Results. Here, we present the observations of the second year of LP15, as well as the final results of the program. The full LP15 sample comprises 190 previously unidentified PSZ2 sources. Of these, 106 objects were studied before, while the remaining sample (except for 6 candidates) has been completed in the second year and is discussed here. In addition to the LP15 sample, we here study 42 additional PSZ2 objects that were originally validated as real clusters because they matched a WISE or PSZ1 counterpart, but they had no measured spectroscopic redshift. In total, we confirm the optical counterparts for 81 PSZ2 sources after the full LP15 program, 55 of them with new spectroscopic information. Forty of these 81 clusters are presented in this paper. After the LP15 observational program the purity of the PSZ2 catalog has increased from 76.7% originally to 86.2%. In addition, we study the possible reasons for false detection, and we report a clear correlation between the number of unconfirmed sources and galactic thermal dust emission.
Evidence for ram-pressure stripping in a cluster of galaxies at z = 0.7
Authors: Boselli A. , Epinat B. , Contini T. , Abril-Melgarejo V. , Boogaard L. A. , Pointecouteau E. , Ventou E. , Brinchmann J. , Carton D. , Finley H. , Michel-Dansac L. , Soucail G. , Weilbacher P. M.
Published: October 2019

Multi-Unit Spectroscopic Explorer (MUSE) observations of the cluster of galaxies CGr32 (M200 ≃ 2 × 1014 M⊙) at z = 0.73 reveal the presence of two massive star-forming galaxies with extended tails of diffuse gas detected in the [O II]λλ3727–3729 Å emission-line doublet. The tails, which have a cometary shape with a typical surface brightness of a few 10−18 erg s−1 cm−2 arcsec−2, extend up to ≃100 kpc (projected distance) from the galaxy discs, and are not associated with any stellar component. All this observational evidence suggests that the gas was removed during a ram-pressure stripping event. This observation is thus the first evidence that dynamical interactions with the intracluster medium were active when the Universe was only half its present age. The density of the gas derived using the observed [O II]λ3729/[O II]λ3726 line ratio implies a very short recombination time, suggesting that a source of ionisation is necessary to keep the gas ionised within the tail.
Nonsurgical management of gastroduodenal tuberculosis: Nine-year experience from a tertiary referral center
Authors: Dalal Ashok , Puri Amarender Singh , Sachdeva Sanjeev , Sakuja Puja
Published: October 2019

Background and study aims Gastroduodenal tuberculosis (GDTB) is an uncommon disease. Surgery has been standard of care both for diagnosis and management of GDTB. The aim of this study was to evaluate the efficacy of non-surgical management of GDTB using a combination of anti-tuberculous therapy (ATT) along with endoscopic dilatation of the tuberculous stricture.

Patients and methods Patients suspected to have gastroduodenal TB were evaluated: clinical, endoscopic, radiological, and histopathological data were recorded. Patients in whom a definite diagnosis of tuberculosis could not be confirmed on mucosal biopsies underwent endoscopic mucosal resection (EMR). Patients were treated with ATT and endoscopic dilatation was done if indicated. Patients were followed up to evaluate clinical, radiological and endoscopic response.

Results Over a 9-year period from 2009 to 2017, 52 patients (mean age 28.5yrs) were diagnosed with GDTB. The most common presenting symptoms were vomiting (n = 51, 98 %) and weight loss (n = 52,100 %). The most common anatomical site of involvement was D1–D2 junction (n = 22, 42 %). Histopathological diagnosis could be made in 43 patients (82.6 %); 36 (69 %) on mucosal biopsies and in 7 of 10 patients (70 %) who underwent snare biopsy/EMR. Endoscopic dilatation was done in 37 patients (71 %) and median dilatation sessions were two. Failure of endotherapy occurred in four patients (7.6 %). All responders had complete amelioration of symptoms after 4 to 6 weeks of combination therapy. Median period of follow-up was 23.5 months and none of the patients reported any recurrence of symptoms.

Conclusion ATT and endoscopic dilatation combined has a high success rate in management of GDTB and should be considered the standard of care.
Thermische Handverletzungen im Kindesalter
Authors: Klein Tobias , Wendenburg Wera , Boemers Thomas M. , Marathovouniotis Nicos
Published: October 2019

Ein gleichbleibend hoher Anteil an thermischen Verletzungen im Kindesalter
betrifft die Hände von Säuglingen und Kleinkindern, wobei Verbrühungen und
Kontaktverbrennungen die häufigsten Unfallursachen darstellen. Während der
Großteil der thermischen Handverletzungen im Kindesalter unter konservativen
Maßnahmen abheilt, führen tiefergradige Verletzungen oft zu Narbenkontrakturen
und narbigen Syndaktylien mit wesentlichen funktionellen Einschränkungen der
kindlichen Hand. Daher sollte bei thermischen Handverletzungen immer ein
differenziertes Vorgehen in Abhängigkeit vom Verletzungsausmaß und der
Lokalisation in einer spezialisierten Einheit erfolgen. Neben der Akuttherapie
ist dabei eine konsequente Nachsorge mit Schienen- und Kompressionsbehandlung,
Physio- und Ergotherapie sowie ggf. operativen Korrekturmaßnahmen von immenser
Bedeutung. Nur so können zufriedenstelle funktionelle und ästhetische Ergebnisse
erzielt werden, damit die jungen Patienten in ihrem Alltag nicht eingeschränkt
werden. Im Rahmen dieses Artikels sollen die wesentlichen Gesichtspunkte in der
Behandlung kindlicher thermischer Handverletzungen belichtet werden.
Hydrogen Rich Water Improved Ventilatory, Perceptual and Lactate Responses to Exercise
Authors: Botek Michal , Krejčí Jakub , McKune Andrew J. , Sládečková Barbora , Naumovski Nenad
Published: October 2019

The potential anti-fatigue and performance benefits of hydrogen rich water (HRW) have resulted in increased research interest over the past 5 years. The aim of this study was to assess physiological and perceptual responses to an incremental exercise protocol after administration of 600 ml HRW within 30 min before exercise. This randomized, double blinded placebo-controlled cross over study included twelve healthy males aged 27.1±4.9 years. The exercise protocol consisted of a 10 min warm-up at 1.0 W.kg−1, followed by 8 min at 2.0, 3.0, and 4.0 W.kg−1, respectively. Cardio-respiratory variables, lactate and ratings of perceived exertion (RPE) were assessed in the last minute of each step. A significantly lower blood lactate was found with HRW (4.0±1.6 and 8.9±2.2 mmol.l−1) compared to Placebo (5.1±1.9 and 10.6±3.0 mmol.l−1) at 3.0, and 4.0 W.kg−1, respectively. Ventilatory equivalent for oxygen and RPE exhibited significantly lower values with HRW (32.3±7.2, and 17.8±1.2 points, respectively) compared to Placebo (35.0±8.4, and 18.5±0.8 points, respectively) at 4 W.kg−1. To conclude, acute pre-exercise supplementation with HRW reduced blood lactate at higher exercise intensities, improved exercise-induced perception of effort, and ventilatory efficiency.
Prediction of ECMO and Mortality in Neonates with Congenital Diaphragmatic Hernia Using the SNAP-II Score
Authors: Kipfmueller Florian , Schroeder Lukas , Melaku Tamene , Geipel Annegret , Berg Christoph , Gembruch Ulrich , Heydweiller Andreas , Bendixen Charlotte , Reutter Heiko , Müller Andreas
Published: October 2019

Background The mortality of neonates with congenital diaphragmatic hernia (CDH) ranges between 20 and 40% even in specialized high-volume centers. The Score for Neonatal Acute Physiology-II (SNAP-II Score) could facilitate the decision about supportive therapies in CDH newborns.

Methods The SNAP-II score consists of the variables arterial blood pressure, pH, PaO2:FiO2, body temperature, diuresis, and seizure activity and was calculated at an age of 12 h.

Results 101 CDH newborns treated in our institution between 2009 and 2017 were included in the study. A SNAP-II score ≥ 28 was calculated as cutoff for predicting mortality (AUC 0.876; 95% CI: 0.795–0.957). The mortality rate was 52.9% with a SNAP-II score ≥ 28, and 5.9% with a SNAP-II score<28. Sensitivity and specificity for predicting mortality was 81.8 and 79.7%, the negative predicting value (NPV) was 94.0%, the positive predicting value (PPV) 52.9%. The optimal cutoff for predicting ECMO was ≥ 22 (AUC 0.895; 95% CI: 0.836–0.954). Sensitivity and specificity for predicting ECMO therapy was 90.7, and 63.8%, the NPV was 90.2%, and the PPV was 65% respectively. The SNAP-II score was independently associated with mortality [OR 1.126 (95% CI: 1.050–1.207)] and the need for ECMO therapy [OR 1.243 (95% CI: 1.106–1.397)].

Conclusion The SNAP-II score is strongly associated with mortality and the need for ECMO therapy in CDH newborns and should be implemented in the risk stratification of these infants.
Morus alba Stem Extract Suppresses Matrix Metalloproteinases (MMP)-1, MMP-9, and Tissue Inhibitors of Metalloproteinase (TIMP)-1 Expression via Inhibition of IκBα Degradation Induced by Porphyromonas gingivalis LPS Signal in THP-1 Cells
Authors: Yiemwattana Ichaya , Kaomongkolgit Ruchadaporn , Wirojchanasak Sodsi , Chaisomboon Niratcha
Published: October 2019

Objectives The aim of this study is to evaluate the inhibitory effects of M. alba stem extract (MSE) on the expression of matrix metalloproteinases (MMP)-1, MMP-9, and tissue inhibitors of metalloproteinase (TIMP)-1 in Porphyromonas gingivalis lipopolysaccharide (LPS)-activated-acute monocytic leukemia cell line (THP-1).

Materials and Methods THP-1 cells were treated with noncytotoxic concentrations of MSE combined with 1 µg/mL of P. gingivalis LPS. The mRNA levels of MMP-1, MMP-9, and TIMP-1 were evaluated via quantitative real-time polymerase chain reaction. The secreted proteins in the culture media were detected by enzyme-linked immunosorbent assay. The degradation of inhibitor of kappa B-alpha (IκBα) protein was tracked by Western blotting.

Statistical Analysis Comparisons in experiments were analyzed with analysis of variance followed by Tukey honestly significant difference comparison test.

ResultsTwenty and 40 µg/mL of MSE significantly downregulated MMP-1 and MMP-9 genes and protein expression but upregulated the gene expression of TIMP-1 (p < 0.05). P. gingivalis LPS induced degradation of IκBα, while addition of MSE (20 and 40 µg/mL) increased IκBα cytosolic levels. MSE was able to suppress the P. gingivalis LPS-induced MMPs expression and also increased the gene expression of TIMP-1 via the inhibition of the cytoplasmic IκBα degradation in THP-1 cells.

Conclusions The present observations suggest that MSE exerted a positive effect on the regulatory mechanism between MMPs and TIMP, which is an important implication for the therapeutic potential of MSE in periodontitis.
Hydroxyapatite in Oral Biofilm Management
Authors: Meyer Frederic , Enax Joachim
Published: October 2019

Particulate hydroxyapatite, Ca5 (PO4)3 (OH), shows a good biocompatibility and is used as a biomimetic ingredient in dental care formulations due to its similarity to human enamel. Numerous studies show its efficiency, for example, in reducing dentin hypersensitivity, and in the remineralization of enamel and dentin. In addition, oral care products with hydroxyapatite improve periodontal health under in vivo conditions. This review article summarizes data on the effects of hydroxyapatite particles in oral biofilm management. Two databases (PubMed and SciFinder) were searched for studies using specific search terms. In contrast to frequently used antibacterial agents for biofilm control, such as chlorhexidine, stannous salts, and quaternary ammonium salts, hydroxyapatite particles in oral care products lead to a reduction in bacterial attachment to enamel surfaces in situ without having pronounced antibacterial effects or showing unwanted side effects such as tooth discoloration. Furthermore, antibacterial agents might lead to dysbiosis of the oral ecology, which was recently discussed regarding pros and cons. Remarkably, the antiadherent properties of hydroxyapatite particles are comparable to those of the gold standard in the field of oral care biofilm management, chlorhexidine in situ. Although biomimetic strategies have been less well analyzed compared with commonly used antibacterial agents in oral biofilm control, hydroxyapatite particles are a promising biomimetic alternative or supplement for oral biofilm management.
Fibrinogen Supplementation and Its Indications
Authors: Grottke Oliver , Mallaiah Shuba , Karkouti Keyvan , Saner Fuat , Haas Thorsten
Published: October 2019

Adequate plasma levels of fibrinogen are essential for clot formation, and in severe bleeding, fibrinogen reaches a critically low plasma concentration earlier than other coagulation factors. Although the critical minimum concentration of fibrinogen to maintain hemostasis is a matter of debate, many patients with coagulopathic bleeding require fibrinogen supplementation. Among the treatment options for fibrinogen supplementation, fibrinogen concentrate may be viewed by some as preferable to fresh frozen plasma or cryoprecipitate. The authors review major studies that have assessed fibrinogen treatment in trauma, cardiac surgery, end-stage liver disease, postpartum hemorrhage, and pediatric patients. Some but not all randomized controlled trials have shown that fibrinogen concentrate can be beneficial in these settings. The use of fibrinogen as part of coagulation factor concentrate based therapy guided by point-of-care viscoelastic coagulation monitoring (ROTEM [rotational thromboelastometry] or TEG [thromboelastography]) appears promising. In addition to reducing patients' exposure to allogeneic blood products, this strategy may reduce the risk of complications such as transfusion-associated circulatory overload, transfusion-related acute lung injury, and thromboembolic adverse events. Randomized controlled trials are challenging to perform in patients with critical bleeding, and more evidence is needed in this setting. However, current scientific rationale and clinical data support fibrinogen repletion in patients with ongoing bleeding and confirmed fibrinogen deficiency.
TaqMan Real-Time Quantification of Epstein-Barr Virus in Severe Early Childhood Caries
Authors: Yildirim Sibel , Yildiz Esma , Kubar Ayhan
Published: October 2019

Objectives: Early childhood caries (ECC) has several risk factors and it is important stressful/ painful events of childhood and immunosuppression may occur during this unique rampant caries pattern. The changes in the host immune competence by compromised cellular immune system functions can activate Epstein Barr virus (EBV). The objective of this study was to determine whether the supragingival plaque samples of severe-ECC (S-ECC) patients harbor more EBV load than the non-carious healthy children by quantitative TaqMan Real-Time polymerase chain reaction (PCR).

Methods: Sixty subjects, including 30 S-ECC patients as well as age and gender matched 30 caries- free patients were studied. The supragingival plaque samples were collected from patients by brushing their teeth for 1 minute and the toothbrush was washed in 1 ml of sterile deionized water. After viral DNA extraction, TaqMan real-time PCR assay was used to quantify EBV DNA. Dental treatments were completed for all S-ECC patients and they were called for routine controls. Only 10 treated S-ECC patients were come to the 3rd months control and post-treatment viral sampling was made in the same manner.

Results: EBV DNA was detected 16 of 30 S-ECC patients and 6 of the healthy controls (P<.001). There was no relationship between baseline and post-treatment samples of 10 treated S-ECC patients.

Conclusions: The results of the study suggest that oro-dental hygiene motives of S-ECC patients might be important contributory factor for S-ECC and EBV would not be involved in the etiopathogenesis of ECC. (Eur J Dent 2010;4:28-33)