bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Materials and Methods from Phospholipase D1 Acts through Akt/TopBP1 and RB1 to Regulate the E2F1-Dependent Apoptotic Program in Cancer Cells
Authors: Kang Dong Woo , Lee Shin Wha , Hwang Won Chan , Lee Bo Hui , Choi Yong-Seok , Suh Young-Ah , Choi Kang-Yell , Min Do Sik
Published: April 2023

1. Plasmids, shRNAs and miRNA. 2. Promoter reporter constructs. 3. 3Â'UTR reporter constructs and site-directed mutagenesis. 4. Viral production and infection. 5. Reagents 6. Transient transfection and reporter gene assay. 7. Real-time quantitative PCR. 8. Quantification of mature miRNA. 9. ChIP assay. 10. mRNA microarray analysis. 11. EpiTect Methyl q-PCR Assay. 12. Mice genotype. 13. PLD activity assay. 14. In vitro limiting dilution assays (LDAs). 15. Additive statistical analysis.
Supplementary Figure S3. The figure shows CNA profile of three IPMN samples. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Authors: Sandhu Vandana , Wedge David C. , Bowitz Lothe Inger Marie , Labori Knut Jørgen , Dentro Stefan C. , Buanes Trond , Skrede Martina L. , Dalsgaard Astrid M. , Munthe Else , Myklebost Ola , Lingjærde Ole Christian , Børresen-Dale Anne-Lise , Ikdahl Tone , Van Loo Peter , Nord Silje , Kure Elin H.
Published: April 2023

The minor allele frequency is in blue and purple is the total copy number.
Supplementary Figure S2. CNA profile of the two xenografts cell lines and their original tumors. from The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Authors: Sandhu Vandana , Wedge David C. , Bowitz Lothe Inger Marie , Labori Knut Jørgen , Dentro Stefan C. , Buanes Trond , Skrede Martina L. , Dalsgaard Astrid M. , Munthe Else , Myklebost Ola , Lingjærde Ole Christian , Børresen-Dale Anne-Lise , Ikdahl Tone , Van Loo Peter , Nord Silje , Kure Elin H.
Published: April 2023

The minor allele frequency is in blue and purple is the total copy number.
Supplemental Table S1. Wnt target genes from Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell States
Authors: Pedersen Elisabeth A. , Menon Rajasree , Bailey Kelly M. , Thomas Dafydd G. , Van Noord Raelene A. , Tran Jenny , Wang Hongwei , Qu Ping Ping , Hoering Antje , Fearon Eric R. , Chugh Rashmi , Lawlor Elizabeth R.
Published: April 2023

Supplemental table S1. RNA-seq differentially expressed genes modulated by Wnt3a (Table S1A) or Wnt3a+RSPO2 (Table S1B).
Supplementary figure 2 from The WASF3–NCKAP1–CYFIP1 Complex Is Essential for Breast Cancer Metastasis
Authors: Teng Yong , Qin Haiyan , Bahassan Abdulaziz , Bendzunas N. George , Kennedy Eileen J. , Cowell John K.
Published: April 2023

Bar graph half tone showing NCKAP1 knockdown
Supplementary figure 1 from The WASF3–NCKAP1–CYFIP1 Complex Is Essential for Breast Cancer Metastasis
Authors: Teng Yong , Qin Haiyan , Bahassan Abdulaziz , Bendzunas N. George , Kennedy Eileen J. , Cowell John K.
Published: April 2023

MS/MS spectrum figure
Figure S3 from BTK Modulates p53 Activity to Enhance Apoptotic and Senescent Responses
Authors: Althubiti Mohammad , Rada Miran , Samuel Jesvin , Escorsa Josep M. , Najeeb Hishyar , Lee Koon-Guan , Lam Kong-Peng , Jones George D.D. , Barlev Nickolai A. , Macip Salvador
Published: April 2023

Supplementary Figure 3. BTK and apoptosis.
Supplemental Figures 1-5 from SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents
Authors: Fiskus Warren , Coothankandaswamy Veena , Chen Jianguang , Ma Hongwei , Ha Kyungsoo , Saenz Dyana T. , Krieger Stephanie S. , Mill Christopher P. , Sun Baohua , Huang Peng , Mumm Jeffrey S. , Melnick Ari M. , Bhalla Kapil N.
Published: April 2023

Supplemental Figure 1. Relative activity of overexpressed SIRT2 in breast cancer cells Supplemental Figure 2. Expression of other sirtuin proteins and HDAC6 in SIRT2 O/E and knockdown cells Supplemental Figure 3. SIRT2 overexpression increases Prdx1 chaperone activity in HEK293 cells treated with H2O2. Supplemental Figure 4. Effects of SIRT2 overexpression on FOXO3A localization Supplemental Figure 5. Schematic of the zebrafish SIRT2 gene and splice-blocking exon 6 morpholino.
Figure S4. CCR4-deficient monocytic MDSCs accumulate at the same level as wild-type monocytic MDSCs in the brain, while granulocytic MDSCs exhibit a mild defect. from CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
Authors: Chang Alan L. , Miska Jason , Wainwright Derek A. , Dey Mahua , Rivetta Claudia V. , Yu Dou , Kanojia Deepak , Pituch Katarzyna C. , Qiao Jian , Pytel Peter , Han Yu , Wu Meijing , Zhang Lingjiao , Horbinski Craig M. , Ahmed Atique U. , Lesniak Maciej S.
Published: April 2023

CD45.1+ recipient mice were irradiated and reconstituted with CD45.1+ WT marrow and CD45.2+ Ccr4-/- marrow. After at least 6 weeks of reconstitution, mice were implanted with GL261 tumors and brain tumor-infiltrating cells were quantified. Data are representative of at least 2 independent experiments. Data are represented as mean {plus minus} SEM; *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 by Student's t test. n.s., not significant.
Supplementary Figure Legends for S1-S16 from Expression of Neuroendocrine Factor VGF in Lung Cancer Cells Confers Resistance to EGFR Kinase Inhibitors and Triggers Epithelial-to-Mesenchymal Transition
Authors: Hwang Wen , Chiu Yu-Fan , Kuo Ming-Han , Lee Kuan-Lin , Lee An-Chun , Yu Chia-Cherng , Chang Junn-Liang , Huang Wen-Chien , Hsiao Shih-Hsin , Lin Sey-En , Chou Yu-Ting
Published: April 2023

'Figure S1. Lack of T790M and amplification of MET in HCC827GR cells; Figure S2. VGF-expressing cells are resistant to rociletinib; Figure S3. VGF expression in neuroendocrine carcinoma and EGFR-TKI resistant cells; Figure S4. VGF is expressed in the independently selected EGFR-TKI resistant HCC827 pool; Figure S5. Correlation of VGF levels with EGFR-TKI resistance and EMT in EGFR-TKI selected single cell clones; Figure S6. Effect of VGF expression on cell survival; Figure S7. VGF is highly expressed in small cell lung cancer; Figure S8. VGF is highly expressed in large cell neuroendocrine carcinoma; Figure S9. Correlation of VGF, CEACAM6, SYP, and CHGB expression levels with IC50 values of gefitinib in EGFR-mutated lung cancer cell lines; Figure S10. EGFR-TKI resistance in H1975 cells expressing differential VGF levels; Figure S11. VGF-TWIST1 signaling encourages EGFR-TKI resistance; Figure S12. Effect of conditioned medium from VGF expressing cells on low serum-mediated growth; Figure S13. Effect of doxycycline alone on tumor cell growth in vitro and in vivo; Figure S14. Correlation of VGF with EMT markers in lung adenocarcinoma; Figure S15. Correlation of neuroendocrine markers or TWIST1 with survival in lung adenocarcinoma; Figure S16. Correlation of neuroendocrine markers or VGF-TWIST1 signature with survival in EGFR-mutated lung adenocarcinoma.'
Supplementary Table S5 from JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers
Authors: Facompre Nicole D. , Harmeyer Kayla M. , Sole Xavier , Kabraji Sheheryar , Belden Zachary , Sahu Varun , Whelan Kelly , Tanaka Koji , Weinstein Gregory S. , Montone Kathleen T. , Roesch Alexander , Gimotty Phyllis A. , Herlyn Meenhard , Rustgi Anil K. , Nakagawa Hiroshi , Ramaswamy Sridhar , Basu Devraj
Published: April 2023

Differentially expressed genes in G0-like vs. bulk LNT14 cells. Columns H-K indicate if gene belongs to GSEA pathways highlighted in this study.
Supplementary Table S2 from JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers
Authors: Facompre Nicole D. , Harmeyer Kayla M. , Sole Xavier , Kabraji Sheheryar , Belden Zachary , Sahu Varun , Whelan Kelly , Tanaka Koji , Weinstein Gregory S. , Montone Kathleen T. , Roesch Alexander , Gimotty Phyllis A. , Herlyn Meenhard , Rustgi Anil K. , Nakagawa Hiroshi , Ramaswamy Sridhar , Basu Devraj
Published: April 2023

QRT-PCR primer sequences.
Supplementary figure legends from Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma
Authors: Liu Yan , Li Yuyang , Wang Xiaoen , Liu Feiyang , Gao Peng , Quinn Max M. , Li Fei , Merlino Ashley A. , Benes Cyril , Liu Qingsong , Gray Nathanael S. , Wong Kwok-Kin
Published: April 2023

There are six supplementary figure legends.
Table S3 from The Damaging Effect of Passenger Mutations on Cancer Progression
Authors: McFarland Christopher D. , Yaglom Julia A. , Wojtkowiak Jonathan W. , Scott Jacob G. , Morse David L. , Sherman Michael Y. , Mirny Leonid A.
Published: April 2023

Table S3 - List of candidate driver alterations used for genomic analysis
S-Figure-5 from Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma
Authors: Liu Yan , Li Yuyang , Wang Xiaoen , Liu Feiyang , Gao Peng , Quinn Max M. , Li Fei , Merlino Ashley A. , Benes Cyril , Liu Qingsong , Gray Nathanael S. , Wong Kwok-Kin
Published: April 2023

In vitro treatment studies of murine Kras/p53 and Kras/p53/Lkb1 cell lines with 5FU or Pemetrexed
Supplemental Information from The Damaging Effect of Passenger Mutations on Cancer Progression
Authors: McFarland Christopher D. , Yaglom Julia A. , Wojtkowiak Jonathan W. , Scott Jacob G. , Morse David L. , Sherman Michael Y. , Mirny Leonid A.
Published: April 2023

Supplemental Methods and Analysis
S-Figure-2 from Gemcitabine and Chk1 Inhibitor AZD7762 Synergistically Suppress the Growth of Lkb1-Deficient Lung Adenocarcinoma
Authors: Liu Yan , Li Yuyang , Wang Xiaoen , Liu Feiyang , Gao Peng , Quinn Max M. , Li Fei , Merlino Ashley A. , Benes Cyril , Liu Qingsong , Gray Nathanael S. , Wong Kwok-Kin
Published: April 2023

FACS analysis of GFP positive Lkb1-null t4 cells carrying resistant Chek1
Figure S2 from The Damaging Effect of Passenger Mutations on Cancer Progression
Authors: McFarland Christopher D. , Yaglom Julia A. , Wojtkowiak Jonathan W. , Scott Jacob G. , Morse David L. , Sherman Michael Y. , Mirny Leonid A.
Published: April 2023

Figure S2 - Comparison of passenger load metrics in cell line experiments and human breast cancers
Figure S5 from PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma
Authors: Yoshino Hirofumi , Nohata Nijiro , Miyamoto Kazutaka , Yonemori Masaya , Sakaguchi Takashi , Sugita Satoshi , Itesako Toshihiko , Kofuji Satoshi , Nakagawa Masayuki , Dahiya Rajvir , Enokida Hideki
Published: April 2023

Metabolites
Figure S2 from PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma
Authors: Yoshino Hirofumi , Nohata Nijiro , Miyamoto Kazutaka , Yonemori Masaya , Sakaguchi Takashi , Sugita Satoshi , Itesako Toshihiko , Kofuji Satoshi , Nakagawa Masayuki , Dahiya Rajvir , Enokida Hideki
Published: April 2023

Gene codis
Supplementary Table S2 from Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence
Authors: Bainor Anthony J. , Deng Fang-Ming , Wang Yu , Lee Peng , Cantor David J. , Logan Susan K. , David Gregory
Published: April 2023

Patient data for the eight SIN3B target genes which are unregulated in human PCa compared to normal tissue and exhibit a significant decrease in disease-free survival following radical prostatectomy.
Supplementary Table S1 from Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence
Authors: Bainor Anthony J. , Deng Fang-Ming , Wang Yu , Lee Peng , Cantor David J. , Logan Susan K. , David Gregory
Published: April 2023

Blinded pathological scoring of mouse cohort was conduced to determine whether prostates were normal, hyperplastic, HGPIN, or carcinoma.
Figure S5 from Chromatin-Associated Protein SIN3B Prevents Prostate Cancer Progression by Inducing Senescence
Authors: Bainor Anthony J. , Deng Fang-Ming , Wang Yu , Lee Peng , Cantor David J. , Logan Susan K. , David Gregory
Published: April 2023

The SIN3B complex is differentially regulated in human PCa. Oncoprint plot of SIN3B, SIN3A, and significantly co-occurring SIN3B target genes. Survival curves of six SIN3B target genes that are upregulated in PCa which demonstrate a decreased disease-free survival rate.
Table S2 from ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage
Authors: Perkhofer Lukas , Schmitt Anna , Romero Carrasco Maria Carolina , Ihle Michaela , Hampp Stephanie , Ruess Dietrich Alexander , Hessmann Elisabeth , Russell Ronan , Lechel André , Azoitei Ninel , Lin Qiong , Liebau Stefan , Hohwieler Meike , Bohnenberger Hanibal , Lesina Marina , Algül Hana , Gieldon Laura , Schröck Evelin , Gaedcke Jochen , Wagner Martin , Wiesmüller Lisa , Sipos Bence , Seufferlein Thomas , Reinhardt Hans Christian , Frappart Pierre-Olivier , Kleger Alexander
Published: April 2023

Description of the genomic alterations in KC and AKC PDAC cell lines
Supplemental Materials and Methods from EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas
Authors: Etemadmoghadam Dariush , Azar Walid J. , Lei Ying , Moujaber Tania , Garsed Dale W. , Kennedy Catherine J. , Fereday Sian , Mitchell Chris , Chiew Yoke-Eng , Hendley Joy , Sharma Raghwa , Harnett Paul R. , Li Jason , Christie Elizabeth L. , Patch Ann-Marie , George Joshy , Au-Yeung George , Mir Arnau Gisela , Holloway Timothy P. , Semple Timothy , Pearson John V. , Waddell Nicola , Grimmond Sean M. , Köbel Martin , Rizos Helen , Lomakin Ivan B. , Bowtell David D.L. , deFazio Anna
Published: April 2023

Supplemental materials and methods
Table S3 from Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer
Authors: Zhang Dongmei , Zhang Gao , Hu Xiaowen , Wu Lawrence , Feng Yi , He Sidan , Zhang Youyou , Hu Zhongyi , Yang Lu , Tian Tian , Xu Weiting , Wei Zhi , Lu Yiling , Flaherty Keith T. , Zhong Xiaomin , Mills Gordon B. , Gimotty Phyllis A. , Xu Xiaowei , Herlyn Meenhard , Zhang Lin
Published: April 2023

Table S3. The lncRNAs and PCGs regulated by Ras in IMR90 cells
Table S2 from Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer
Authors: Zhang Dongmei , Zhang Gao , Hu Xiaowen , Wu Lawrence , Feng Yi , He Sidan , Zhang Youyou , Hu Zhongyi , Yang Lu , Tian Tian , Xu Weiting , Wei Zhi , Lu Yiling , Flaherty Keith T. , Zhong Xiaomin , Mills Gordon B. , Gimotty Phyllis A. , Xu Xiaowei , Herlyn Meenhard , Zhang Lin
Published: April 2023

Table S2: Probe set in the custom designed lncRNA microarray
Supplementary Materials and Methods from CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib
Authors: Sen Triparna , Tong Pan , Stewart C. Allison , Cristea Sandra , Valliani Aly , Shames David S. , Redwood Abena B. , Fan You Hong , Li Lerong , Glisson Bonnie S. , Minna John D. , Sage Julien , Gibbons Don L. , Piwnica-Worms Helen , Heymach John V. , Wang Jing , Byers Lauren Averett
Published: April 2023

This file contains additional details of materials and methods used in this study like SCLC cell line authentication, targeted knockdown of CHK1 and MYC, PCR, cell viability aasay, cell cycle analysis, generation of tumor models, RPPA and immunofluorescence.
Supp Figure 3 from Nuclear CD24 Drives Tumor Growth and Is Predictive of Poor Patient Prognosis
Authors: Duex Jason E. , Owens Charles , Chauca-Diaz Ana , Dancik Garrett M. , Vanderlinden Lauren A. , Ghosh Debashis , Leivo Mariah Z. , Hansel Donna E. , Theodorescu Dan
Published: April 2023

Examples of masking used to quantify total cellular and nuclear CD24.
Supplemental Fig. 4 from Enhanced Therapeutic Efficacy and Memory of Tumor-Specific CD8 T Cells by Ex Vivo PI3K-δ Inhibition
Authors: Abu Eid Rasha , Ahmad Shamim , Lin Yuan , Webb Mason , Berrong Zuzana , Shrimali Rajeev , Kumai Takumi , Ananth Sudha , Rodriguez Paulo C. , Celis Esteban , Janik John , Mkrtichyan Mikayel , Khleif Samir N.
Published: April 2023

In vivo data from an experiment starting the therapy at a later date with larger starting tumor size
Figure S1 from Modeling Cytostatic and Cytotoxic Responses to New Treatment Regimens for Ovarian Cancer
Authors: Falcetta Francesca , Bizzaro Francesca , D'Agostini Elisa , Bani Maria Rosa , Giavazzi Raffaella , Ubezio Paolo
Published: April 2023

Comparison of the tumor growth curves of single-drug PTX and two-drugs DDP/PTX treatments with the expected curve for the DDP/PTX combination
Dataset S1 from Nrf2 Mutagenic Activation Drives Hepatocarcinogenesis
Authors: Ngo Hoang Kieu Chi , Kim Do-Hee , Cha Young-Nam , Na Hye-Kyung , Surh Young-Joon
Published: April 2023

Dataset S1. Overall survival analysis for HCC patients with or without Nrf2 mutations
Supplementary Table 1 from HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1
Authors: Vandyke Kate , Zeissig Mara N. , Hewett Duncan R. , Martin Sally K. , Mrozik Krzysztof M. , Cheong Chee Man , Diamond Peter , To L. Bik , Gronthos Stan , Peet Daniel J. , Croucher Peter I. , Zannettino Andrew C.W.
Published: April 2023

Table of genes dysregulated with overexpression of HIF-2alpha in LP-1 cells
Supplementary Table from Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine
Authors: Goto Norihiro , Ueo Taro , Fukuda Akihisa , Kawada Kenji , Sakai Yoshiharu , Miyoshi Hiroyuki , Taketo Makoto Mark , Chiba Tsutomu , Seno Hiroshi
Published: April 2023

Antibodies and qRT-PCR primers used in this study
Supplementary Figure 1 from Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine
Authors: Goto Norihiro , Ueo Taro , Fukuda Akihisa , Kawada Kenji , Sakai Yoshiharu , Miyoshi Hiroyuki , Taketo Makoto Mark , Chiba Tsutomu , Seno Hiroshi
Published: April 2023

Hes1 expression is upregulated in intestinal stem cells.
Supplemental table 1 from Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies
Authors: Bui Mai H. , Lin Xiaoyu , Albert Daniel H. , Li Leiming , Lam Lloyd T. , Faivre Emily J. , Warder Scott E. , Huang Xiaoli , Wilcox Denise , Donawho Cherrie K. , Sheppard George S. , Wang Le , Fidanze Steve , Pratt John K. , Liu Dachun , Hasvold Lisa , Uziel Tamar , Lu Xin , Kohlhapp Fred , Fang Guowei , Elmore Steven W. , Rosenberg Saul H. , McDaniel Keith F. , Kati Warren M. , Shen Yu
Published: April 2023

Anti-proliferative activity of ABBV-075 across cancer cell lines
Figure S6 from β-Adrenergic Signaling in Mice Housed at Standard Temperatures Suppresses an Effector Phenotype in CD8+ T Cells and Undermines Checkpoint Inhibitor Therapy
Authors: Bucsek Mark J. , Qiao Guanxi , MacDonald Cameron R. , Giridharan Thejaswini , Evans Lauren , Niedzwecki Brian , Liu Haichao , Kokolus Kathleen M. , Eng Jason W.-L. , Messmer Michelle N. , Attwood Kristopher , Abrams Scott I. , Hylander Bonnie L. , Repasky Elizabeth A.
Published: April 2023

This data shows that housing mice at 30 degrees Celsius improves the efficacy of anti-PD-1 in both 4T1 and B16-OVA tumor-bearing mice indicating that cool housing temperatures (22 degrees C) impairs the efficacy of anti-PD-1 in murine tumor models.
Supplemental figure 20 from Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies
Authors: Bui Mai H. , Lin Xiaoyu , Albert Daniel H. , Li Leiming , Lam Lloyd T. , Faivre Emily J. , Warder Scott E. , Huang Xiaoli , Wilcox Denise , Donawho Cherrie K. , Sheppard George S. , Wang Le , Fidanze Steve , Pratt John K. , Liu Dachun , Hasvold Lisa , Uziel Tamar , Lu Xin , Kohlhapp Fred , Fang Guowei , Elmore Steven W. , Rosenberg Saul H. , McDaniel Keith F. , Kati Warren M. , Shen Yu
Published: April 2023

ABBV-075 inhibits hypoxia induced transcription of proangiogenesis factors
Figure S4 from Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression
Authors: Wang Li-Ting , Chiou Shyh-Shin , Chai Chee-Yin , Hsi Edward , Yokoyama Kazunari K. , Wang Shen-Nien , Huang Shau-Ku , Hsu Shih-Hsien
Published: April 2023

Figure S4, A to I, The ISX mRNA expression showed a strong correlation with the mRNA expression of well-known immunosuppressive genes, including IDO1 (A), TDO2 (C), KYNU (D), AHR (E), CD80 (F), CD86 (G), PD-L1 (H) and RB (I) in HCC tumors. B, The ISX mRNA expression was highly correlated with kynurenine (KYN, nM/Î¼g protein) levels in tumors part of HCC patients.
Supplementary Methods from Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity
Authors: Zheng Shunsheng , Koh Xin Yu , Goh Hui Chin , Rahmat Siti Aishah B. , Hwang Le-Ann , Lane David P.
Published: April 2023

Contains primer sequences, additional materials and methods to complement main article.
Figure S3 from Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity
Authors: Zheng Shunsheng , Koh Xin Yu , Goh Hui Chin , Rahmat Siti Aishah B. , Hwang Le-Ann , Lane David P.
Published: April 2023

Supplementary Figure S3. Related to Figure 3. C646 reduces the stabilization of p53 protein.
Supplementary methods from STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway
Authors: Jin Lin , Vu Trung , Yuan Guandou , Datta Pran K.
Published: April 2023

This file contains more details for some main methods in the manuscript.
Figure S2 from Acetylation of Mastermind-like 1 by p300 Drives the Recruitment of NACK to Initiate Notch-Dependent Transcription
Authors: Jin Ke , Zhou Wen , Han Xiaoqing , Wang Zhiqiang , Li Bin , Jeffries Shawn , Tao Wensi , Robbins David J. , Capobianco Anthony J.
Published: April 2023

Identification of Maml1 acetylation sites
Supplementary table 3 from Loss of FAM46C Promotes Cell Survival in Myeloma
Authors: Zhu Yuan Xiao , Shi Chang-Xin , Bruins Laura A. , Jedlowski Patrick , Wang Xuewei , Kortüm K. Martin , Luo Moulun , Ahmann Jonathan M. , Braggio Esteban , Stewart A. Keith
Published: April 2023

Pathway analysis of the genes differentially expressed after introduction of FAM46C. The genes were determined as differentially expressed after introduction of FAM46C in two myeloma cell lines were submitted to Ingenuity Pathway Analysis (IPA,http://www.ingenuity.com/) for pathway enrichment analysis. The results of top twenty four pathways affected were shown.
Table S2. from Posttranscriptional Upregulation of IDH1 by HuR Establishes a Powerful Survival Phenotype in Pancreatic Cancer Cells
Authors: Zarei Mahsa , Lal Shruti , Parker Seth J. , Nevler Avinoam , Vaziri-Gohar Ali , Dukleska Katerina , Mambelli-Lisboa Nicole C. , Moffat Cynthia , Blanco Fernando F. , Chand Saswati N. , Jimbo Masaya , Cozzitorto Joseph A. , Jiang Wei , Yeo Charles J. , Londin Eric R. , Seifert Erin L. , Metallo Christian M. , Brody Jonathan R. , Winter Jordan M.
Published: April 2023

Table S2. Patient Cohort Characteristics
Supplemental Figure 1 from Androgen Receptor Supports an Anchorage-Independent, Cancer Stem Cell-like Population in Triple-Negative Breast Cancer
Authors: Barton Valerie N. , Christenson Jessica L. , Gordon Michael A. , Greene Lisa I. , Rogers Thomas J. , Butterfield Kiel , Babbs Beatrice , Spoelstra Nicole S. , D'Amato Nicholas C. , Elias Anthony , Richer Jennifer K.
Published: April 2023

Immunohistochemistry for AR in BT549 cells cultured in attached or forced suspension culture conditions.
SFigure 2 from Dual Targeting of Insulin Receptor and KIT in Imatinib-Resistant Gastrointestinal Stromal Tumors
Authors: Chen Weicai , Kuang Ye , Qiu Hai-Bo , Cao Zhifa , Tu Yuqing , Sheng Qing , Eilers Grant , He Quan , Li Hai-Long , Zhu Meijun , Wang Yuexiang , Zhang Rongqing , Wu Yeqing , Meng Fanguo , Fletcher Jonathan A. , Ou Wen-Bin
Published: April 2023

This file shows that coordinated inhibition of IR and KIT has additive effect on cell viability in imatinib-resistant GIST cell line. This Figure is supplied in support of Figure 3B.
SFigure 1 from Dual Targeting of Insulin Receptor and KIT in Imatinib-Resistant Gastrointestinal Stromal Tumors
Authors: Chen Weicai , Kuang Ye , Qiu Hai-Bo , Cao Zhifa , Tu Yuqing , Sheng Qing , Eilers Grant , He Quan , Li Hai-Long , Zhu Meijun , Wang Yuexiang , Zhang Rongqing , Wu Yeqing , Meng Fanguo , Fletcher Jonathan A. , Ou Wen-Bin
Published: April 2023

This file contains immunoblot evaluations of phospho-EGFR and EGFR expression in GIST cell lines to support Figure 1A.
supplemental table s1,s2 and s3 from Epstein–Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages
Authors: Huang Di , Song Shi-Jian , Wu Zi-Zhao , Wu Wei , Cui Xiu-Ying , Chen Jia-Ning , Zeng Mu-Sheng , Su Shi-Cheng
Published: April 2023

Supplemental Table S1. Baseline characteristics of NPC patients of training and validation cohort. Supplemental Table S2. Predicted cutoff for the number of CD68 or CCL18 CD68 cells in nasopharyngeal carcinoma of training cohort analysed by X-tile. Supplemental Table S3. Correlation of CCL18 Expressing TAM Counts with Clinicopathological Status in training cohort (321 Cases) and validation cohort (259 cases) of Patients with nasopharyngeal carcinoma.
supplemental figure s6 from Epstein–Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages
Authors: Huang Di , Song Shi-Jian , Wu Zi-Zhao , Wu Wei , Cui Xiu-Ying , Chen Jia-Ning , Zeng Mu-Sheng , Su Shi-Cheng
Published: April 2023

Figure S6 related to Figure 6. The interaction between EBV+NPC cells and macrophages promotes metastasis in a humanized mouse model.
supplemental figure s4 from Epstein–Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages
Authors: Huang Di , Song Shi-Jian , Wu Zi-Zhao , Wu Wei , Cui Xiu-Ying , Chen Jia-Ning , Zeng Mu-Sheng , Su Shi-Cheng
Published: April 2023

Figure S4 related to Figure 4. NF-κB mediates cytokine production in NPC cells with active EBV replications
Supplementary Figure 1 from Monitoring the Vascular Response and Resistance to Sunitinib in Renal Cell Carcinoma In Vivo with Susceptibility Contrast MRI
Authors: Robinson Simon P. , Boult Jessica K.R. , Vasudev Naveen S. , Reynolds Andrew R.
Published: April 2023

Susceptibility contrast MRI data acquired from a representative 786-0 RCC xenograft.
supplemental figure s2 from Epstein–Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages
Authors: Huang Di , Song Shi-Jian , Wu Zi-Zhao , Wu Wei , Cui Xiu-Ying , Chen Jia-Ning , Zeng Mu-Sheng , Su Shi-Cheng
Published: April 2023

Figure S2 related to Figure 2. NPC cells with different EBV replications exhibit distinctive capacity to recruit and activate macrophages
Supplemental Materials and Methods from Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair
Authors: Piacente Francesco , Caffa Irene , Ravera Silvia , Sociali Giovanna , Passalacqua Mario , Vellone Valerio G. , Becherini Pamela , Reverberi Daniele , Monacelli Fiammetta , Ballestrero Alberto , Odetti Patrizio , Cagnetta Antonia , Cea Michele , Nahimana Aimable , Duchosal Michel , Bruzzone Santina , Nencioni Alessio
Published: April 2023

Supplemental Materials and Methods shows experimental methods, including the immunohistochemical (IHC) analysis of NAPRT expression in primary ovarian cancer and the cloning of NAPRT-EGFP and of wild type NAPRT.
supplemental Figure s5 from Epstein–Barr Virus-Induced VEGF and GM-CSF Drive Nasopharyngeal Carcinoma Metastasis via Recruitment and Activation of Macrophages
Authors: Huang Di , Song Shi-Jian , Wu Zi-Zhao , Wu Wei , Cui Xiu-Ying , Chen Jia-Ning , Zeng Mu-Sheng , Su Shi-Cheng
Published: April 2023

Figure S5 related to Figure 5. TAMs induce EMT and enhance the invasiveness of NPC cells through CCL18
Supplementary_table 1-6, 8-12 from Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma
Authors: Yuan Jiang , Jiang Yan-Yi , Mayakonda Anand , Huang Moli , Ding Ling-Wen , Lin Han , Yu Fenggang , Lu Yanan , Loh Thomas Kwok Seng , Chow Marilynn , Savage Samantha , Tyner Jeffrey W. , Lin De-Chen , Koeffler H. Phillip
Published: April 2023

The IC50 (nM) values, RNA-seq, ChIP seq and motif analysis in NPC cell lines
Figure S1 from Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair
Authors: Piacente Francesco , Caffa Irene , Ravera Silvia , Sociali Giovanna , Passalacqua Mario , Vellone Valerio G. , Becherini Pamela , Reverberi Daniele , Monacelli Fiammetta , Ballestrero Alberto , Odetti Patrizio , Cagnetta Antonia , Cea Michele , Nahimana Aimable , Duchosal Michel , Bruzzone Santina , Nencioni Alessio
Published: April 2023

Figure S1 shows the frequency of QPRT, NMRK1, and NMRK2 gene amplification in human tumors and NAPRT expression in common human cancers.
Tables S6, S7 from Competition between DNA Methylation, Nucleotide Synthesis, and Antioxidation in Cancer versus Normal Tissues
Authors: Cao Sha , Zhu Xiwen , Zhang Chi , Qian Hong , Schuttler Heinz-Bernd , Gong Jianping , Xu Ying
Published: April 2023

Table S6: Steady state when Vmax of TS changes; Table S7: Steady state when H2O2 concentration changes.
Supplemental materials and methods from ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas
Authors: Grausam Katie B. , Dooyema Samuel D.R. , Bihannic Laure , Premathilake Hasitha , Morrissy A. Sorana , Forget Antoine , Schaefer Amanda M. , Gundelach Justin H. , Macura Slobodan , Maher Diane M. , Wang Xin , Heglin Alex H. , Ge Xijin , Zeng Erliang , Puget Stephanie , Chandrasekar Indra , Surendran Kameswaran , Bram Richard J. , Schüller Ulrich , Talyor Michael D. , Ayrault Olivier , Zhao Haotian
Published: April 2023

This section provides detailed information on experimental procedures and data analysis methods.
Supplemental Table 2 from KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1
Authors: Gao Yu , Li Hongzhao , Ma Xin , Fan Yang , Ni Dong , Zhang Yu , Huang Qingbo , Liu Kan , Li Xintao , Wang Lei , Gu Liangyou , Yao Yuanxin , Ai Qing , Du Qingshan , Song Erlin , Zhang Xu
Published: April 2023

The comparison of KLF6 expressions in Non-metastatic and Metastatic specimens by immunohistochemical staining.
Supplemental Table 1 from Retention of Interstitial Genes between TMPRSS2 and ERG Is Associated with Low-Risk Prostate Cancer
Authors: Murphy Stephen J. , Kosari Farhad , Karnes R. Jeffrey , Nasir Aqsa , Johnson Sarah H. , Gaitatzes Athanasios G. , Smadbeck James B. , Rangel Laureano J. , Vasmatzis George , Cheville John C.
Published: April 2023

Clinicopath data and case event summary
Table A and B from Cancer-Associated Fibroblasts Share Characteristics and Protumorigenic Activity with Mesenchymal Stromal Cells
Authors: Borriello Lucia , Nakata Rie , Sheard Michael A. , Fernandez G. Esteban , Sposto Richard , Malvar Jemily , Blavier Laurence , Shimada Hiroyuki , Asgharzadeh Shahab , Seeger Robert C. , DeClerck Yves A.
Published: April 2023

A: List of antibodies used in the study B: Clinical characteristics of patients from which CAF-MSC and BM-MSC were isolated.
Supplementary Table S1 from NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas
Authors: Su Xiaoping , Zhang Jianping , Mouawad Roger , Compérat Eva , Rouprêt Morgan , Allanic Frederick , Parra Jérôme , Bitker Marc-Olivier , Thompson Erika J. , Gowrishankar Banumathy , Houldsworth Jane , Weinstein John N. , Tost Jorg , Broom Bradley M. , Khayat David , Spano Jean-Philippe , Tannir Nizar M. , Malouf Gabriel G.
Published: April 2023

List of ccRCCs from TCGA dataset assessed for DNA methylation using Infinium 450K arrays. One column lists the DNA methylation subgroup to which each ccRCC sample belongs (CIMP= C-CIMP; CIMPL= low-CIMP; CIMPN= no-CIMP).
Figure S2 from Immune-Related Gene Expression Profiling After PD-1 Blockade in Non–Small Cell Lung Carcinoma, Head and Neck Squamous Cell Carcinoma, and Melanoma
Authors: Prat Aleix , Navarro Alejandro , Paré Laia , Reguart Noemí , Galván Patricia , Pascual Tomás , Martínez Alex , Nuciforo Paolo , Comerma Laura , Alos Llucia , Pardo Nuria , Cedrés Susana , Fan Cheng , Parker Joel S. , Gaba Lydia , Victoria Iván , Viñolas Nuria , Vivancos Ana , Arance Ana , Felip Enriqueta
Published: April 2023

Kaplan-Meier survival analysis based on selected genes or gene signatures.
Figure S3 from Normal and Malignant Cells Exhibit Differential Responses to Calcium Electroporation
Authors: Frandsen Stine K. , Krüger Mie B. , Mangalanathan Uma M. , Tramm Trine , Mahmood Faisal , Novak Ivana , Gehl Julie
Published: April 2023

Figure S3. Tumor necrosis after treatment with different doses of calcium electroporation MDA-MB231 (human breast cancer) tumors treated with different doses of calcium electroporation: 168 mM CaCl2 injected in a volume equivalent to 20% - 80% of tumor volume and 100 - 500 mM CaCl2 injected in a volume equivalent to half the tumor volume. Calcium concentration is shown per tumor volume. Fraction of necrosis was estimated by stereological point counting of tumors removed 2 days after treatment. Each data point is shown together with linear regression for tumors treated with or without electroporation. Data points for controls are shown in the left panel in grey symbols. Ranges for controls, samples treated with electroporation, and treated without electroporation is shown left of the graph. EP = electroporation. n = 4-5 for treated and n = 3 for untreated/sham treated.
Figure S7 from Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities
Authors: Méndez-Lucas Andrés , Li Xiaolei , Hu Junjie , Che Li , Song Xinhua , Jia Jiaoyuan , Wang Jingxiao , Xie Chencheng , Driscoll Paul C. , Tschaharganeh Darjus F. , Calvisi Diego F. , Yuneva Mariia , Chen Xin
Published: April 2023

Silencing PKM1/2 did not affect c-Myc/Mcl1 driven liver tumor development
Figure S5 from Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities
Authors: Méndez-Lucas Andrés , Li Xiaolei , Hu Junjie , Che Li , Song Xinhua , Jia Jiaoyuan , Wang Jingxiao , Xie Chencheng , Driscoll Paul C. , Tschaharganeh Darjus F. , Calvisi Diego F. , Yuneva Mariia , Chen Xin
Published: April 2023

PKM2 and PKLR expression in c-MYC-shLuc/MCL1 and c-MYC-shPKM/MCL1 tumors
Supplemental Figure legends from Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy
Authors: Bartee Mee Y. , Dunlap Katherine M. , Bartee Eric
Published: April 2023

Legends for supplemental figures.
Supplementary Table S1 from A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer
Authors: Kloosterman Wigard P. , Coebergh van den Braak Robert R.J. , Pieterse Mark , van Roosmalen Markus J. , Sieuwerts Anieta M. , Stangl Christina , Brunekreef Ronne , Lalmahomed Zarina S. , Ooft Salo , van Galen Anne , Smid Marcel , Lefebvre Armel , Zwartkruis Fried , Martens John W.M. , Foekens John A. , Biermann Katharina , Koudijs Marco J. , Ijzermans Jan N.M. , Voest Emile E.
Published: April 2023

Colon tumor sample overview, clinical characteristics, fusion genes and KRAS, NRAS, BRAF mutation status and sequencing statistics.
Supplementary Data file from A Systematic Analysis of Oncogenic Gene Fusions in Primary Colon Cancer
Authors: Kloosterman Wigard P. , Coebergh van den Braak Robert R.J. , Pieterse Mark , van Roosmalen Markus J. , Sieuwerts Anieta M. , Stangl Christina , Brunekreef Ronne , Lalmahomed Zarina S. , Ooft Salo , van Galen Anne , Smid Marcel , Lefebvre Armel , Zwartkruis Fried , Martens John W.M. , Foekens John A. , Biermann Katharina , Koudijs Marco J. , Ijzermans Jan N.M. , Voest Emile E.
Published: April 2023

Combined supplementary data file containing: -extended materials and methods, describing details of sample collection and isolation, sequencing data generation, cell culturing and protein analysis. -Supplementary Figure S1 showing patient inclusion in this study -Supplementary Figure S2 showing RT-PCR results of fusion gene verification -Supplementary Figure S3 showing Exonic and protein structure of three BRAF fusions -Supplementary Figure S4 showing the structure of an EML4-NTRK3 fusion gene and exonic expression of NTRK3 -Supplementary Figure S5 showing the structure and expression of a novel RRBP1-RET fusion -Supplementary Figure S6 showing the structure and expression of a novel USP9X-ERAS fusion gene. -Supplementary Figure S7 showing Rspondin fusion gene detection and expression -List of Three Supplementary Tables -Supplementary References
Supplemental Figure 3 from Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy
Authors: Bartee Mee Y. , Dunlap Katherine M. , Bartee Eric
Published: April 2023

Expression of PDL1 on B16/F10 tumor cells in vivo following MYXV treatment.
Supplemental Figure 2 from Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy
Authors: Bartee Mee Y. , Dunlap Katherine M. , Bartee Eric
Published: April 2023

Efficacy and Specificity of antibody depletion in vivo.
Supplementary Data from Pharmacokinetics and Drug Interactions Determine Optimum Combination Strategies in Computational Models of Cancer Evolution
Authors: Chakrabarti Shaon , Michor Franziska
Published: April 2023

Supplemental data for the main manuscript. Contains derivations of main formulae used in text, analysis of different dosing schedules, estimation of parameters for the TATTON trial and discussions regarding assumptions made in the analysis.
Supplementary Figure legends from Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer
Authors: Jin Lingyan , Garcia Jesse , Chan Emily , de la Cruz Cecile , Segal Ehud , Merchant Mark , Kharbanda Samir , Raisner Ryan , Haverty Peter M. , Modrusan Zora , Ly Justin , Choo Edna , Kaufman Susan , Beresini Maureen H. , Romero F. Anthony , Magnuson Steven , Gascoigne Karen E.
Published: April 2023

Supplementary Figure legends
Supplementary Table 1 from LSD1 Inhibitor T-3775440 Inhibits SCLC Cell Proliferation by Disrupting LSD1 Interactions with SNAG Domain Proteins INSM1 and GFI1B
Authors: Takagi Shinji , Ishikawa Yoshinori , Mizutani Akio , Iwasaki Shinji , Matsumoto Satoru , Kamada Yusuke , Nomura Toshiyuki , Nakamura Kazuhide
Published: April 2023

Supplementary Table S1: Genes up-regulated or down-regulated in H1417, H510A, or H526 cell line upon T-3775440 treatment.
Supplementary figures and tables from IGFBP7 Deletion Promotes Hepatocellular Carcinoma
Authors: Akiel Maaged , Guo Chunqing , Li Xia , Rajasekaran Devaraja , Mendoza Rachel G. , Robertson Chadia L. , Jariwala Nidhi , Yuan Fang , Subler Mark A. , Windle Jolene , Garcia Dawn K. , Lai Zhao , Chen Hung-I Harry , Chen Yidong , Giashuddin Shah , Fisher Paul B. , Wang Xiang-Yang , Sarkar Devanand
Published: April 2023

Fig. S1 describes creation of Igfbp7-/- mice. Fig. S2 shows histology of different organs of Igfbp7 / and -/- mice. Fig. S3 shows images of senescent hepatocytes. Fig. S4 shows quantification of all Western blots. Fig. S5 shows histology and GS staining of DEN-induced tumors. Fig. S6 shows immune profile of naive adult liver and spleen. Fig. S7 shows tumorigenesis of HCC cells co-injected with macrophages. Fig. S8 shows antigen presentation of WT dendritic cells. Fig. S9 shows histology and immunohistochemistry of Igfbp7 overexpressing tumors. Table S1 shows the list of differentially expressed genes. Table S2 shows downregulation of genes of antigen presentation pathway.
Supplementary Materials, methods, figures, and tables. from Sensitivity to BUB1B Inhibition Defines an Alternative Classification of Glioblastoma
Authors: Lee Eunjee , Pain Margaret , Wang Huaien , Herman Jacob A. , Toledo Chad M. , DeLuca Jennifer G. , Yong Raymund L. , Paddison Patrick , Zhu Jun
Published: April 2023

Supplementary Data includes Supplementary Materials and Methods (cell culture protocols, methods for predicting BUB1BR/S status and extracting molecular profiles of GBM tumor cells, genome-wide shRNA screens, GBM cohort data, drug sensitivity measurement, and etc.) Supplementary Figures, Supplementary Tables, and references for the supplementary. Here is a list of Supplementary Figures and Tables: Fig. S1: Principal component analysis (PCA) of gene expression levels, related to Fig. 1. Fig. S2: Gene set enrichment analysis of the 838 BUB1BS/R-associated genes, related to Fig. 1. Fig. S3: Cross-validation of the elastic net classifier, related to Fig. 1. Fig. S4: Expression features based on tumor tissue and GSC, related to Fig. 2 and Fig. 5. Fig. S5: Association between predicted BUB1B-inhibition sensitivity values and clinical information, related to Fig. 2 and Table 1. Fig. S6: BUB1BS and BUB1BR-specific sub-networks, related to Fig. 3. Fig. S7: Expression difference between BUB1BS GSCs and BUB1BR GSCs, related to Fig. 3. Fig. S8: The Predicted BUB1B-inhibition sensitivity values of glioma cell lines, related to Fig. 4. Fig. S9: Boxplot of drug sensitivity for glioma cell lines, related to Fig. 4. Fig. S10: Application of BUB1BR/S classifier to single cell RNA-seq data of two stemlike tumor-propagating glioblastoma cells, related to Discussion. Fig. S11: Application of BUB1BR/S classifier to single cell RNA-seq data, related to Discussion. Fig. S12: The application of BUB1B classifier to population controls, related to Discussion. Table S1: Summary of GSC samples and prediction of BUB1B sensitivity for GSC cell lines based on expression levels, related to Fig. 1. Table S2: Composition of each cell type based on tumor tissue expression levels, related to Fig. 5. Table S3: Association between BUB1BS/R status and survival rate, related to Fig. 2 and Table 1. Table S4: Normalized cell growth (%) of 9217B and 10647B for etoposide treatment, related to Fig. 5.
Supplementary Table S2 from A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents
Authors: Azan Antoine , Caspers Peter J. , Bakker Schut Tom C. , Roy Séverine , Boutros Céline , Mateus Christine , Routier Emilie , Besse Benjamin , Planchard David , Seck Atmane , Kamsu Kom Nyam , Tomasic Gorana , Koljenović Senada , Noordhoek Hegt Vincent , Texier Matthieu , Lanoy Emilie , Eggermont Alexander M.M. , Paci Angelo , Robert Caroline , Puppels Gerwin J. , Mir Lluis M.
Published: April 2023

Summary of cutaneous adverse events at the different time point for each patient included in this study. n/a: not available
Supplementary Information from A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents
Authors: Azan Antoine , Caspers Peter J. , Bakker Schut Tom C. , Roy Séverine , Boutros Céline , Mateus Christine , Routier Emilie , Besse Benjamin , Planchard David , Seck Atmane , Kamsu Kom Nyam , Tomasic Gorana , Koljenović Senada , Noordhoek Hegt Vincent , Texier Matthieu , Lanoy Emilie , Eggermont Alexander M.M. , Paci Angelo , Robert Caroline , Puppels Gerwin J. , Mir Lluis M.
Published: April 2023

Revised Supplementary Information
Legends for supplementary data from Kindlin-2 Regulates the Growth of Breast Cancer Tumors by Activating CSF-1–Mediated Macrophage Infiltration
Authors: Sossey-Alaoui Khalid , Pluskota Elzbieta , Bialkowska Katarzyna , Szpak Dorota , Parker Yvonne , Morrison Chevaun D. , Lindner Daniel J. , Schiemann William P. , Plow Edward F.
Published: April 2023

This file contains legends for figures supplied as supplementary data
Supplementary Figure S1 from A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents
Authors: Azan Antoine , Caspers Peter J. , Bakker Schut Tom C. , Roy Séverine , Boutros Céline , Mateus Christine , Routier Emilie , Besse Benjamin , Planchard David , Seck Atmane , Kamsu Kom Nyam , Tomasic Gorana , Koljenović Senada , Noordhoek Hegt Vincent , Texier Matthieu , Lanoy Emilie , Eggermont Alexander M.M. , Paci Angelo , Robert Caroline , Puppels Gerwin J. , Mir Lluis M.
Published: April 2023

Mean LD score for the validation data set for Stratum Corneum skin layer for MEK inhibitors (A), EGFR inhibitors (B) and BRAF inhibitors (C) and for Viable Epidermis skin layer for MEK inhibitors (D), EGFR inhibitors (E) and BRAF inhibitors (F). The p-value between the two groups is reported. In the 6 conditions, the p-value is lower than 0.001%.
Figure S4 from Kindlin-2 Regulates the Growth of Breast Cancer Tumors by Activating CSF-1–Mediated Macrophage Infiltration
Authors: Sossey-Alaoui Khalid , Pluskota Elzbieta , Bialkowska Katarzyna , Szpak Dorota , Parker Yvonne , Morrison Chevaun D. , Lindner Daniel J. , Schiemann William P. , Plow Edward F.
Published: April 2023

This figure contains tumor measurement and macrophage staining and quantification of macrophage infiltration of control 4T1 and K2-defficient-4T1-derived tumors of roughly similar sizes. This Figure is supplied in support of Figure 3I.
Figure S3 from Kindlin-2 Regulates the Growth of Breast Cancer Tumors by Activating CSF-1–Mediated Macrophage Infiltration
Authors: Sossey-Alaoui Khalid , Pluskota Elzbieta , Bialkowska Katarzyna , Szpak Dorota , Parker Yvonne , Morrison Chevaun D. , Lindner Daniel J. , Schiemann William P. , Plow Edward F.
Published: April 2023

This figure contains macrophage staining and quantification of macrophage infiltration of control MDA-MB-231 and K2-defficient-MDA-MB-231-derived tumors of roughly similar sizes. This Figure is supplied in support of Figure 3F.
Supplementary Figures and Tables from miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells
Authors: Lulla Amriti R. , Slifker Michael J. , Zhou Yan , Lev Avital , Einarson Margret B. , Dicker David T. , El-Deiry Wafik S.
Published: April 2023

Supplementary Figures 1-5 and Supplementary Tables 1-3
Table S1-S3 from Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis
Authors: Hsiao Kuei-Yang , Lin Ya-Chi , Gupta Sachin Kumar , Chang Ning , Yen Laising , Sun H. Sunny , Tsai Shaw-Jenq
Published: April 2023

Table S1. Sequences of siRNA oligonucleotides used in this study. Table S2. Sequences of primers for quantitative PCR. Table S3. Sequences of primers for cloning.
Supplementary figures with figure legends from Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Growth and Metastasis
Authors: Hsiao Kuei-Yang , Lin Ya-Chi , Gupta Sachin Kumar , Chang Ning , Yen Laising , Sun H. Sunny , Tsai Shaw-Jenq
Published: April 2023

Figure S1. Alignments between full-length read to exon(s). Figure S2. CircRNAs validation in CRC. Figure S3. Sanger sequencing results for the backsplice junction. Figure S4. Hypoxia tunes the levels of linear and circular CCDC66 transcripts. Figure S5. CircCCDC66 reshapes the tumor transcriptome. Figure S6. CircCCDC66 regulates a subset of oncogenes. Figure S7. Levels of circCCDC66 from xenografted tumors.
Supplementary Movie 3 from The Blebbishield Emergency Program Overrides Chromosomal Instability and Phagocytosis Checkpoints in Cancer Stem Cells
Authors: Jinesh Goodwin G. , Kamat Ashish M.
Published: April 2023

Time-lapse movie showing the fusion between spheres during the transformation phase of blebbishield emergency program in LNCaP cells. Live LNCaP cells were induced to undergo apoptosis and blebbishield formation and then subjected to transformation. The transformation phase was subjected to time-lapse microscopy, which showed the fusion between transformed spheres. Note the weak attachment of spheres to the substratum.