bluuebunny/crossref_metadata_2025 huggingface dataset:
Lymphocyte-platelet adhesion, eosinophil and IgE ige concentration in children with obstructive bronchitis
Authors: Vlasova A. N. , Vitkovsky Yu. A.
Published: April 2022

Aim. To study lymphocytic-platelet adhesion, eosinophils and IgE concentration in children with acute obstructive bronchitis.

   Materials and methods. 70 children were examined, the first group consisted of children with acute bronchitis (n=38), the second group included healthy children (n=32). All children were examined for the concentration of IgE, the number of lymphocytes and eosinophils, and the count of lymphocyte-platelet aggregates.

   Results. In patients with obstructive bronchitis, there was no difference in the concentration of the relative and absolute number of lymphocytes compared with healthy children. High values of eosinophils were found in children with obstructive bronchitis (9.0 ± 0.7 %) while in children of the control group the same indicator was determined within the limits of normal values (0.9 ± 0.2 %). The level of IgE in children with obstructive bronchitis exceeded the concentration of this indicator in healthy children by 19 times. In children with obstructive bronchitis, the index and degree of lymphocyticplatelet adhesion were 20.0 ± 0.7 % and 10.5 ± 0.09, respectively, statistically significantly higher than similar indices in healthy children (14.0 ± 0.2 %, p = 0.0001 and 3.3 ± 0.1, p = 0.001, respectively).

   Conclusion. In the body of children with obstructive bronchitis, an immune response develops, which is involved in the pathogenesis of recurrence of the disease, the causes of which are infectious agents that stimulate innate immunity due to the presentation of PAMP molecules, as well as adaptive immunity, accompanied by killer reactions, the production of immunoglobulins, including IgE.
Interrelation of immunological and hemodynamic parameters of the fetoplacental system in exacerbation of chronic bronchitis of cytomegalovirus etiology
Authors: Kolosov V. P. , Gorikov I. N. , Andrievskaya I. A. , Odireev A. N. , Nakhamchen L. G. , Bushmanov A. V.
Published: April 2022

Aim. To establish the relationship of immunological and hemodynamic parameters of the fetoplacental system during exacerbation of chronic bronchitis of cytomegalovirus etiology.

   Materials and methods. A study was carried out of the concentration of TNFα, IgA, IgM in the blood serum and the systolic-diastolic ratio (SDR) in the right uterine artery (RUA) in 80 women in the second trimester of pregnancy, uncomplicated and complicated by exacerbation of cytomegalovirus infection (CMVI). Three groups were retrospectively distinguished. The first group included 30 patients with CMV seronegative physiological pregnancy, the second group included 25 women with exacerbation of chronic bronchitis caused by CMVI reactivation, initiating the development of chronic compensated placental insufficiency (CCPI), in the third group – 25 pregnant women with chronic bronchitis in the acute stage, induced by CMVI, leading to the formation of chronic subcompensated placental insufficiency (CSPI) in the third trimester of gestation.

   Results. In the first group, the concentration of TNFα in the blood serum was Me 16.4 (13.1–33.8) pg/mL, IgA – Me 2.5 (2.23–2.62) mg/mL, IgM – Me 0.99 (0.87–1.56) mg/mL, and SDR in RUA – Me 1.95 (1.87–2.30). In the second group, compared with the first one, there was an increase in the concentration of TNFα by 4.95 times (p=0.000001), IgM − by 2.51 times (p = 0.000001) and SDR in RUA by 1.25 times (p = 0.000001) with a 1.49-fold decrease in the IgA level (p = 0.000001). In the third group, compared with the first one, there was an increase in TNFα by 6.12 times (p = 0.000001), IgM − by 2.98 times (p = 0.000001) and the value of SDR in RUA by 1.70 times (p = 0.000001) against the background of a 2.31-fold decrease in IgA concentration (p = 0.000001). In patients of the third group, in comparison with the second group, higher levels of TNFα (by 1.23 times, p = 0.000001), IgM (by 1.18 times, p = 0.000001) and SDR in the RUA (by 1.35 times, p = 0.000001), as well as lower values of the IgA concentration (1.54 times, p = 0.000001).

   Conclusion. In women with exacerbation of chronic bronchitis caused by CMVI reactivation, leading to the formation of CSPI, in contrast to patients with a similar bronchopulmonary pathology of cytomegalovirus origin and the development of CCPI, a more pronounced activation of the systemic inflammatory response and an imbalance in the humoral component of immune system lead to an increase in vascular resistance in the RUA pool.
Disturbance of utero-placental-fetus blood flow in pregnant women with community-acquired pneumonia of bacterial and viral (COVID-19) etiology
Authors: Аbuldinov А. S. , Аndrievskaya I. А.
Published: April 2022

Introduction. Placental insufficiency is one of the most frequently developing complications in pregnant women with acute respiratory failure, which is a consequence of community-acquired pneumonia (CAP), including viral etiology. The impact of COVID-19 infection on the course of pregnancy, the condition of the fetus and newborns has not been studied enough.

   Aim. To study the state of uteroplacental-fetal circulation, placenta and fetus in women with bacterial and COVID-19-associated CAP in the second and third trimesters of pregnancy.

   Materials and methods. The history of childbirth and the results of examinations of 120 women in the second and third trimesters of pregnancy were analyzed, including 37 women with moderate CAP of bacterial etiology, 48 women with COVID-19 infection. The comparison group consisted of 35 women with uncomplicated pregnancy. The state of the placenta and fetus was assessed according to the data of ultrasound and utero-placental-fetal blood flow – Doppler study. Pulsation indices (PI) and cerebro-placental ratio (CPR) were analyzed.

   Results. According to our data, the risk of developing chronic placental insufficiency in pregnant women with COVID-19-associated CAP of moderate severity was higher than in groups of women with CAP of bacterial etiology and in the comparison group. In groups with CAP, significant differences were found in the indices of CPR, PI of the uterine arteries, umbilical cord arteries and middle cerebral artery, corresponding to I (A, B) or II degree of disturbance of the uteroplacental and/or placental-fetal blood flow. Chronic intrauterine fetal hypoxia and fetal growth retardation were more frequently detected in the group with COVID-19-associated CAP. Newborns born to mothers with COVID-19 infection have an increased risk of neonatal damage to the central nervous system (CNS).

   Conclusion. COVID-19-associated CAP, compared with CAP of bacterial etiology, increases the risk of chronic placental insufficiency, intrauterine fetal hypoxia and fetal growth retardation, and the development of neonatal CNS damage.
Assessment of the main indicators of morbidity and mortality in cancer patients with oral lesions in the eastern regions of Russia
Authors: Gordienko V. P. , Filippova Е. V.
Published: April 2022

Over the past decades, the eastern regions of Russia are characterized by a constant in-crease in the number of patients with oncological pathology, in the structure of which malignant neoplasms of the respiratory system occupy the first place in the cause of death.

   Aim. A scientific assessment of the main indicators of morbidity and mortality of the population from the cancer of oral organs in the Far East of Russia (2008-2020).

   Materials and methods. The morbidity and mortality rates, reporting forms of statistical records of cancer patients and regulatory documents of superior organizations, information on observations of the dynamics of changes in the numerical values of the pathology under study were used in the course of the work.

   Results. We present the main indices of morbidity and mortality of patients with oral cancer in the eastern regions of the Russian Federation where 596 new cases of malignant neoplasms were registered in 2020, which is 53.7 % more than thirteen years ago (in 2008 – 320 people). There was a similar increase of 76.7 % for Russia. During the studied period of time the number of patients with I-II stages of disease has increased (in 2020 – 39.5 %; in 2008 – 27.6 %) with simultaneous increase of the number of patients with advanced forms of the disease (in 2020 – 33.7 %; in 2008 – 25.9 %). In recent years the morbidity and mortality rates have been steadily increasing. The percentage of actively diagnosed patients has declined (in 2020 – 23.5 %; in 2019 – 24.3 %), while at the end of the year contingent accumulation index has become higher (4.5 %). Morphological confirmation of the diagnosis (over 95.4 %) did not exceed the national average (98.3 %). The ratio of patients who had been on the registry for 5 and more years was lower than the average Russian values, but the mortality rate during the first year after the diagnosis has improved (in 2020 – 28.0 %; in 2008 – 42.0 %).

   Conclusion. Thus, against the background of increasing total number of patients with malignant neoplasms in the territories of the eastern regions of the Russian Federation there is a steady increase in morbidity and mortality in oral cancer.
Interleukin 8 and bronchial eosinophils in patients with asthma and cold airway hyperresponsiveness
Authors: Pirogov A. B. , Prikhodko A. G. , Perelman J. M.
Published: April 2022

Introduction. Cold airway hyperresponsiveness (CAHR) is common in patients with asthma. The effect of inhaled corticosteroid/long-acting β2-agonist therapy (ICS / LABA) on its severity, and the role of IL-8, and the eosino-philic profile of bronchial inflammation have not been studied.

   Aim. To study the dynamic relationship between the level of IL-8 and eosinophilic inflammation in the bronchi of asthma patients with CAHR using anti-inflammatory combined therapy with ICS / LABA.

   Materials and methods. Patients with asthma (n=59) received ICS / LABA for 24 weeks. The level of disease control (ACT, points), cellular composition of induced sputum (IS), bronchial response (ΔFEV1IHCA, %) to 3-minute isocapnic hyperventilation with cold (-20ºС) air (IHCA) was assessed. Exhaled breath condensate (EBC) was collected before and after the IHCA, in which the concentration of IL-8 (pg/mL) was determined.

   Results. Group 1 included 28 patients with CAHR (ΔFEV1IHCA = -14.1 ± 1.7%), group 2 included 31 patients with no response to cold bronchoprovocation (ΔFEV1IHCA = - 3.0 ± 2.4 %, p < 0.0001). Initially, patients of groups 1 and 2 had no differences in ACT (16.8±0.6 and 15.7 ± 0.8 points), FEV1 (92.5 ± 3.6 and 87.8 ± 2.2%), the number of eosinophils in sputum (8.0 ± 2.4 and 4.7 ± 1.3%, respectively, p > 0.05). The concentration of IL-8 before and after the IHCA test in group 1 was 131.2 ± 18.0 and 146.3 ± 23.5 pg/mL, respectively (p > 0.05), in group 2 it was 130.5 ± 8.8 and 149.9 ± 18.4 pg/mL, respectively (p>0.05). After treatment, the airway response to the IHCA significantly decreased in group 1 (ΔFEV1IHCA = - 8.8 ± 1.5 %, p < 0.01), in group 2 it remained unchanged (- 3.6 ± 1.3 %, p > 0.05). The level of asthma control in group 1 increased to 20.7 ± 1.6 ACT points (p < 0.01), in group 2 – up to 19.7 ± 1.7 (p < 0.05). The lung function did not change. After treatment, the level of IL-8 before and after the IHCA in group 1 did not change (89.8 ± 11.7 and 85.5 ± 7.8 pg/mL, p > 0.05), as did the number of eosinophils (8.0 ± 2.4 and 6.2 ± 3.1 %, p > 0.05). In group 2, the level of IL-8 before and after IHCA decreased from 89.2 ± 7.7 to 73.9 ± 10.3 pg/mL (p < 0.01), the concentration of eosinophils decreased from 4.7 ± 1.3 up to 1.5 ± 0.57 % (p < 0.05).

   Conclusion. 24-week therapy with ICS/LABA in patients with CAHR leads to improved asthma control, a decrease in the severity of cold bronchospasm, without being accompanied by changes in the level of IL-8, which affects the dynamics of the concentration of eosinophils in the bronchi.
Melanoma with respiratory damage
Authors: Grigorenko A. A. , Voytsekhovskiy V. V. , Roshchin S. N. , Filatova E. A.
Published: April 2022

Aim. Demonstration of cases of melanoma of rare localization – with damage to the respiratory system.   Materials and methods. A brief review of the literature on non-skin melanomas is presented; special attention is paid to melanomas of airways and lungs, primary localization and metastatic lesions. Clinical observations of this pathology are given.

   Results. The paper presents two rare cases from the personal practice of the authors: the diagnosis of primary melanoma of the paranasal sinuses with germination of the base of the skull and metastatic lung damage, in which it was difficult to determine the primary localization of the tumor. In both cases, differential diagnosis was carried out with other formations in the respective areas. The final diagnosis was made by histological and immunohistochemical studies.

   Conclusion. The diagnosis of melanoma with damage to the respiratory organs requires differential diagnosis with other formations of this localization. A histological and immunohistochemical study helps to establish the final diagnosis.
Ajaran Moderatisme Beragama pada Tradisi Ngunjeng Tandhe
Authors: Rahem Zaitur
Published: April 2022

Konsep moderasi agama dalam sejumlah kajian keilmuan selama ini dijabarkan diantaranya berupa cinta kasih antar sesama, harmoni, keseimbangan, keadilan, dan potensi moderasi lainnya. Kerukunan umat beragama di kabupaten Sumenep sudah sejak lama terjalin. Hubungan baik antar pemeluk agama yang satu dengan lainnya erat dan kuat. Bahkan kedekatan keeratan tersebut berefek terhadap kesadaran masyarakat Madura untuk luwes dalam mengawinkan kebudyaan dan praktik agama. Salah satunya, masyarakat di kabupaten Sumenep memadukan budya lokal dalam miniature praktik yang sarat dengan ajaran agama Islam. Seperti kebiasaan ngunjeng tandhe’ pada hari pernikahan. Adapun fokus penelitian ini adalah : pertama, sejak kapan kebiasan tandhe’ menjadi bagian integeral dari praktik ajaran beragama masyarakat kabupaten Sumenep Madura Jawa Timur. Kedua, Apa yang melatarbelakangi masyarakat di Kabupaten Sumenep ngunjeng tandhe’ sebagai hiburan dalam walimatu al-Ursy? Ketiga, seperti apa wujud ajaran pendidikan antiradikalisme pada budaya ngunjeng tandhe’ dan pertautan agama Islam dengan budaya lokal kabupaten Sumenep? Keempat, apa dampak positif pergelutan agama dengan budaya lokal terhadap kehidupan beragama masyarakat dalam konteks masyarakat lokal kabupaten Sumenep Madura? Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian lapangan. Objek yang diteliti adalah tradisi ngunjeng tandhe’ yang dilaksanakan sejumlah warga di kabupaten Sumenep Madura. Penulis mengumpulkan data melalui studi dokumentasi, interview dan observasi. Data yang dikumpulkan penulis analisis secara baik dan sistematis.
Romantika Sistem Bernegara dalam Wacana Keislaman
Authors: Yasin Nur , Slamet Slamet , Amina Siti
Published: April 2022

Islam is par excellence in its position as a resource of reference for every field of life. Islam provides regulatory guidelines starting from the smallest social level to the broadest scale, namely the state. The state as the largest social community has a great responsibility because it deals with the affairs of a large society. The Islamic state system had become a public discourse in the late twentieth and early twentieth centuries. The bearers of the ideology of the Islamic state display their ideas by including figures as legitimacy, including Sayyid Qutb and al-Mawdudi. His arguments are accompanied by the interpretation of the Qur'anic version of the characters' interpretations. In state theory, there are two forms of state, republic and monarchy. While the state system there are four kinds, namely nomocracy, democracy, aristocracy and theocracy. For the bearers of the ideology of the Islamic state, it is said that the Islamic state system has its own characteristics and is independent which is not the same as the theory of the state in general. The Islamic state aspires to form a supranational state that binds all state barriers so that there is no longer a state in the form of a national state. This discourse has become an endless debate. Some figures say that the supranational system is a utopian concept. With this debate, the Islamic state system becomes an unfinished romantic discourse.
Otoritas dan Kekuasaan Kiai Menjaga Komitmen Sumber Daya Manusia Beda Agama di Pondok Pesantren Bali Bina Insani Tabanan Bali
Authors: Sudarsono Sudarsono
Published: April 2022

The commitment of human resources in an organization is very important and influences the work relations. Organizational commitment cannot be separated from the term loyalty. Loyalty and commitment is a unity that has a confusing meaning. In simple terms, loyalty means how long employees work and obey the leadership's orders. This shows that maintaining commitment is an obligation for leaders. The commitment of human resources within the Bali BinaInsani Islamic Boarding School cannot be separated from the authority and power of the kiai as a leader. The kiai in the pesantren organization is the holder of full authority and power who can determine the path in maintaining the commitment of human resources of religious.
"SLAMETHAN ASSÎR" as A Media of Harmonization between Individual Happiness and Social Peace
Authors: Arifin Samsul
Published: April 2022

The kiai of the Besuki Residency  in the past, had local wisdom in carrying out social harmonization to achieve mutual happiness. One of them is through "Slamethan Assîr" which is carried out by the community so that they can grow and develop in their careers. This study aims to understand the meaning of achieving happiness and prosperity in life through "Slamethan Assîr" and its implementation in career development, from the perspective of self-concept theory of career development. This research uses the ethnographic method. The results of this study indicate that "Slamethan Assîr" means as a guide that a career must contain the value of worship, hoping for blessings for the family, and giving charity to maintain harmony with neighbors. Career development is a process of developing self-concept; self-quality and competence and paying attention to the environmental context. The standard of career success is to feel prosperous and happy with family, friends, or neighbors and must be in line with the pleasure of Allah. So they will avoid corrupt, fraudulent, and other heinous acts. This research is useful for the development of the psychology of entrepreneurship and career
Bank Wakaf Mikro The Moderation Effect on Islamic Microfinance Preference in East Java
Authors: Rofiqoh Siti Nur Indah , Sukmana Raditya , Rufaidah Anik
Published: April 2022

There are many institutions in East Java Such as Sharia Kopwan, Baitul Maal Wat Tanwiil (BMT) and also Bank Wakaf Mikro (BWM), but they have many problems including the moderation effect. It caused by many factors like Islamic product design, Islamic product business and Islamic Good Governance implementation. The purpose of this study is to investigate the moderation effect of BWM in East Java. This paper was conducted qualitatively with a multiple case studies approach in six cash waqf institution in East Java. It was conducted that the moderation in BWM had similarities correction in product design management of fund, using ijaroh. The Islamic product business were chosen to the productive poor around the Islamic Boarding School and should to academic mission. Last, to upgrade Islamic good governance, BWM ought to collect the waqf funds directly, exclude LAZNAS BSM UMAT.
Islamic Institution Students and Understanding Multiculturalism (Case Study at Institut Agama Islam Tarbiyatut Lamongan)
Authors: Farokhah Fiqih Aisyatul
Published: April 2022

This research aims to analyze the understanding of Islamic college students toward multiculturalism. Some of the problems studied are (1) the reasons for the importance of studying multiculturalism for students, (2) the forms of planting multiculturalism values based on Islamic religion for students of the Islamic Institute Tarbiyatut Tholabah (Tabah) Lamongan (3) the implications of multiculturalism on the understanding of IAI Tabah students about multiculturalism. This study uses qualitative data analysis methods. Multiculture already exists in Islamic teachings called Tasamuh. Tasamuh is a mubalaghah from samaha which means tolerance. Tasamuh is an open attitude that recognizes the diversity of ethnic groups, races, skin colors, languages, customs, cultures, languages, and religions. Multicultural education must include the concepts of diversity, respect, justice, tolerance, racism, prejudice, discrimination, and stereotypes. The results show that multiculturalism is important to be taught to students to realize Islamic moderation or Wasathiyah Islam. Activities are directed to support the multiculturalism of campus life. However, IAI Tabah students' understanding of multiculturalism is diverse.
Moderation of Islamic Education in The Digital Space
Authors: Ulum Miftachul , Mun'im Abdul
Published: April 2022

This Narrative of hatred, provocation and fights of sheep built by some digital media users without considering other users can easily broadcast hatred and even cause brutality. Users of digital media must be wiser and more moderate in understanding and not easily provoked. Research on moderation of Islamic education is very important for digital media users. How to understand the moderation of Islamic education within the scope of digital space. How to form a moderate attitude in the scope of digital space. How strategies realize moderation of Islamic education in digital space. The understanding of moderate souls for digital media users will greatly affect the attitude and decision so it is not easy to be provoked in reading the narratives that corner one of the groups
Innovative Human Resource Management in Georgian Public Schools
Authors: Murad Pakhuridze Murad Pakhuridze
Published: April 2022

At the current stage of development of human resource management, the modern requirements for the school need to be constantly reformed and restructured, and it is also important to define the role of management in this area. Since the goals, objectives and content of school management are determined by the objective needs and requirements of the society, it is necessary to study them taking into account the current trends in the development of the educational institution. This is especially true in the face of the ever-increasing challenges facing the school and, consequently, the management of the learning process organized in it. Today, the human resource management of Georgian public schools needs to change its attitude towards goal-oriented methods, deviate from the traditional forms of its organization, change the subject-object relationship, and restructure the structure. Certification and upgrading of human resources in Georgian public schools requires significant changes in the practical activities of school administration. Insufficient theoretical elaboration of the problem of innovations in human resource management and the necessity of introducing innovations in management practice, made it necessary to introduce a modern trend of human capital management in modern public schools "Innovations in Modern School Management".
Keywords: Innovation, certification, structure, methodology, restructuring.
The Management of Human Resources Focused on the Success of the Organization
Authors: Saba Burjaliani Saba Burjaliani
Published: April 2022

In the article: "The management of human resources focused on the success of the organization" - is an example that if the human resources in the organization are properly managed, then the organization will be successful. This function is assigned to the personnel management service in the organization. The article emphasizes that personnel management services in Georgian organizations are very weak. Mostly non-professionals work there, as there is a large shortage of staff managers in Georgia. The author considers that such specialization doesn’t exist in Georgian higher education institutions.
The article discusses the four styles of personnel manager-directive, persuasive, participatory, delegating, and gives managers advice on when, in what situations, to use them. It also lists the conditions on which each of them must be based. The author concludes that personnel managers need to believe that employees can do a lot of good for the success of the organization. All they need to do is respect their personal interests and appreciate the work they do.
Keywords: Orientation on success; management of human resources; Personnel Manager; Employee interest.
Methods of Evaluating the Effectiveness of the Management of a Medical Organization
Authors: Rusudan Bulbulashvili Rusudan Bulbulashvili , Tamar Rostiashvili Tamar Rostiashvili
Published: April 2022

The article discusses the development of the activities of the medical organization, which aims to continuously improve the quality of medical care. The authors believe that this is possible only in the case of quality and new goal-oriented and planned work monitoring. According to the authors, this allows for constant improvement of the organization. The authors believe that despite the growing interest of the heads of medical organizations in improving the quality of medical organizations, the interpretation of the criteria for self-assessment may be complicated and sometimes even incomprehensible.
According to the authors, criteria such as customer relationship system, procedural approach, stakeholders, social responsibility, information security, etc. are sometimes inadequately used in healthcare. Developing new management technologies requires the adoption and sharing of a quality philosophy by managers and staff.
Keywords: Management philosophy, efficiency, evaluation methods.
The Features of the Marketing System in Agricultural Organizations
Authors: Jemma Saakyan Jemma Saakyan , Lia Berikashvili Lia Berikashvili
Published: April 2022

The implementation of marketing systems is important in the daily activities of agricultural organizations. Agro marketing operates in the specific conditions of production, promotion and sale of agricultural products, which determines the features of the functioning mechanism of agricultural marketing. The aim of this article is to identify and analyze the key elements of agro marketing, the impact of which is significant on the activities of the organization, including: the direct dependence of agricultural products on natural and climatic conditions, the importance of products to consumers according to food safety conditions, seasonality, different levels of marketing activity, incomplete regulators in the field of marketing activities, etc. The analysis of the identified elements allows us to develop the right policy of marketing activities in agricultural organizations and increase the level of implementation of systems.
Keywords: Agro Business, Marketing System, Natural Resources, Seasonality, Food Security, Regulation.
The Impact of Financial Technologies on Digital Transformation of Accounting, Audit and Financial Reporting
Authors: Natia Shengelia Natia Shengelia , Zhuzhuna Tsiklauri Zhuzhuna Tsiklauri , Agnieszka Rzepka Agnieszka Rzepka , Revaz Shengelia Revaz Shengelia
Published: April 2022

FinTech is a combination of Finance and Technology which involves use of modern smart technology like big data analytics, cloud computing, artificial intelligence, machine learning, and robotics, for doing finance. Financial technology development has influenced nearly all financial services industry, from granting to insurance, from accounting to consultancy, from consumer finance to investment banking. As a result of digital transformation, preparation of XBRL-based structured digital Financial Reports, block-chain trading, accounting of new digital assets, cryptocurrency has assigned more strategic functions to accountants, while simultaneously supported the auditing to reduce the risk at the minimum level.
In order to obtain or retain competitive advantage it is essential to invest money, time into implementing in innovations. A cloud system is part of the basic infrastructure now. When the entire business model changes so do change the ways of accounting, auditing and financial reporting that are inevitable components of business. The integration of modern digital technologies into finances, has enabled finance professionals to achieve greater efficiency, work speed, and financial transparency.
Keywords: Financial technologies; Digital Accounting and IFRS; Cryptocurrency; Blockchain; XBRL-standard; Audit; Financial Reporting;
Current Approaches and Prospects of Urban and Suburban Mobility in Europe
Authors: Steffen Hütter Steffen Hütter , Dominik Schug Dominik Schug
Published: April 2022

Mobility is a reflection of social challenges. Changes in society and its diverse lifeworlds are influencing people's everyday mobility behavior. Megatrends around digitalization, globalization, urbanization, and sustainability are increasingly influencing our environment and forcing new approaches and ways of thinking with regard to individual and collective mobility behavior. "Cities are growing nowadays and so is their citizens' demand for mobility." Cities are becoming food points and spaces where different interests meet. In addition to high standards of living and personal flexibility, these living and cultural spaces should also offer optimal accessibility and, last but not least, be designed to be sustainable and attractive. In view of the current need for a mobility transformation, in particular to reduce climate-hostile exhaust gases, special attention is being paid to current and future research in the mobility sector in the following five key topics: First: electric mobility using renewable energy; Second: "Mobility on Demand" and "Mobility as a Service" as the two decisive business models of the future with regard to CO2 reduction and logistics efficiency increase; Third: autonomous and automated driving; Fourth: creation and optimization of new charging infrastructure in urban and suburban areas and Fifth: contemporary and future-oriented urban mobility concepts to be subsumed under the term "Last Mile Logistic" with special consideration of commuter and small-scale cargo logistics. The special challenges in dealing with these research topics lie both in the high complexity of the subject matter and in the necessary interdisciplinarity with which the questions must be approached. Thus, only research teams will be able to produce resilient and robust results that are composed of specialists from the fields of logistics, computer science, energy management, lawyers, architects and urban planners, engineers, and programmers, and many more disciplines. The formation and organization of such research teams is the basis for successful mobility research and represents the real challenge of urban mobility change.
Keywords: Urban and Suburban Mobility, Logistics, Sustainability, digitalization, globalization.
Socio-economic Trends and Prospects for the Development of the Mineral Industry in the Global Economy
Authors: Gela Lobjanidze Gela Lobjanidze
Published: April 2022

The article discusses the global trends in the development of mineral-resource potential and the current aspects of the effective use of its individual forms in the economy in terms of a greener, safer and more sustainable future; The demand for mineral raw materials is also analyzed, taking into account the dynamics of the economy, the solution of critical challenges and the main directions of development. It is proposed to produce minerals and metals responsibly in order to promote sustainable economic growth, their safe use through the involvement of ethical business practices and other important trends.
Key words: Mineral Resource Potential, Mineral Raw Materials, COVID-19, Global Trends, Economy, Green, Safe and Sustainable Development.
The Impact of Migration Processes on the Adolescents of Parents Emigrating from Georgia
Transnational Parenthood
Authors: Natalia Chubinidze Natalia Chubinidze
Published: April 2022

Migration, and migration processes have long influenced the socio-political, economic, demographic or social structure of a country. The abovementioned phenomenon has been an integral part of the development of mankind and it still is. In the modern, globalizing world, in an era of scientific technological change and the deepening of relations between people, the issue of human mobility holds one of the key places in world politics. In scientific or political discussions, the question of how the human mobility can be used for a country’s development and not the other way around, gains more and more popularity. That is why migration management issues have been incorporated in the Sustainable Development Goals (SDGs) or in other similar documents, which are made not only for a specific country, but also for the harmonious development of the world, on which world leaders are working. It is also noteworthy that in 2018, the member states of the United Nations adopted a totally independent document, Global Compact for Safe, Orderly and Regular Migration. The document was the first such large scale attempt to develop a comprehensive approach on migration management issues. All in all, it is clear that Georgia cannot be an exception to this global process. The issue examined in the article about the challenges of migrant parents, especially children of emigrant mothers left in the homeland, unfortunately, mostly attracts the attention of the public and the media when dealing with a specific antisocial, tragic or unfortunate fact. Nevertheless, it is already clear at a first glance, that the topic is highly relevant, requiring a professional structural and strategic approach and not only a symptomatic response. Despite numerous important steps taken to improve migration management processes in Georgia in recent years, the issue examined in this article does not lose its urgency.
In general, the cornerstone of Georgia's migration policy should certainly be a balanced migration management policy, which, on the one hand will allow people to gain work experience abroad and improve living conditions. However, all this should happen on a temporary, legal basis and not for a long term or permanently, especially through the means of irregular migration.
Keywords: Migration and development; Children of emigrants; Generation grown up through electronic means of communication; Balanced legal migration; Prevention of Irregular migration.
Analisis Potensial Saham Sektor Kesehatan dengan Pendekatan Teknikal. Studi Sentiment Positif Covid-19
Authors: Nurlela Nurlela , Yudiawan Markiz
Published: April 2022

Dalam setiap transaksi perdagangan saham, investor atau manajer investasi dihadapkan kepada pilihan untuk membeli atau menjual saham. Setiap kesalahan dalam pengambilan keputusan investasi, akan menimbulkan kerugian bagi investor. Oleh karena itu perlu dilakukan analisis yang akurat dan dapat diandalkan untuk dijadikan dasar pengambilan keputusan investasi. Ada dua macam analisis dalam dunia investasi saham yaitu analisis fundamental dan analisis teknikal. Penelitian ini bertujuan untuk menganalisis sentimen positif vaksin covid-19 dengan Analisa teknikal pada saham sektor kesehatan. Hasil penelitian ini menunjukkan terdapat enam saham yang memiliki kinerja terbaik dengan perdagangan saham yang tinggi. Pada penelitian ini juga peneliti merumuskan beberapa pertimbangan teknikal yang perlu dipertimbangkan investor dalam buy or hold suatu saham.
Effective Treatment Against Healing Newborn Cord Wounds with Closed and Open Techniques at Nene Mallomo Hospital Sidrap Regency
Authors: Hasliani Hasliani
Published: April 2022

The purpose of the study identified effective treatments against healing newborn cord wounds with closed and open techniques. The study used the Experimental Quasy (Post Test Only Contorl Group Design) design to outline the causal relationship with the involvement between the control group and the experimental group. Random selection of both groups. The population is a newborn weighing at least 2500 mg, uncomplicated and treated. The sample is a newborn baby treated in the Perinatology Room. Questionnaires are used as data collection sheets to supplement general data from birth and family/maternal data. The results of the study were closed techniques, cord wound healing by 30% healed "quickly", as many as only 3 respondents in closed techniques, the umbilical cord was released for less than 6 days due to the umbilical cord which tended to be moist due to evaporation of alcohol within 2 minutes. In open technique, the healing of cord wounds is as partial Cord wound healing by 60% healed "quickly" which means as many as 6 respondents whose umbilical cords were released for less than 6 days because the umbilical cord tended to be less moist and dry faster after exposure to air. Closed and open technical treatment on newborn cord wounds quantitatively does not have a significant difference to the healing of cord wounds (p = 0.280), but qualitatively open technical treatment is better because by not giving or applying anything on the umbilical cord and leaving it exposed to air, the wound will dry faster. Closed technical treatment using an alcohol compress that is only effective in 2 minutes and then evaporates causing the umbilical cord to dampen and the healing process will be slower.
Enriched Pro-Categories and Shapes
Authors: Uglešić Nikica
Published: April 2022

Given a category C and a directed partially ordered set J, a certain category proJ-C on inverse systems in C is constructed such that the ordinary pro-category pro-C is the most special case of a singleton J ≡ {1}. Further, the known pro*-category pro*-C becomes proN-C. Moreover, given a pro-reflective category pair (C, D), the J-shape category ShJ(C, D) and the corresponding J-shape functor SJ are constructed which, in mentioned special cases, become the well known ones. Among several important properties, the continuity theorem for a J-shape category is established. It implies the “J-shape theory” is a genuine one such that the shape and the coarse shape theory are its very special instances.
La despenalización del consumo de drogas: Una mirada desde el neotomismo y el derecho constitucional comparado
Authors: Gramajo Castro Juan Pablo
Published: April 2022

Este trabajo aborda la despenalización del consumo de drogas desde la perspectiva filosófica del iusnaturalismo neotomista, con base en el tratamiento del tema en el derecho constitucional de otros países. Se exponen las justificaciones de algunos Tribunales Constitucionales para estimar inconstitucional la prohibición o penalización de la conducta, sobre la base de derechos como la intimidad y la vida privada, el libre desarrollo de la personalidad, la libertad de acción y el examen de proporcionalidad. Se discuten las posturas contrapuestas a que puede conducir el pensamiento de Tomás de Aquino, según se enfatice el carácter pedagógico de la ley humana o sus limitaciones como la posible tolerancia de ciertos males.
Ciberjusticia 3.0: Cuando la tecnología encuentra la justicia
Authors: Archila Valle Ennio Paolo
Published: April 2022

Se examina la incidencia que la tecnología ha tenido en el derecho a nivel general y en la justicia a nivel particular; explicándose cómo el modelo de justicia tradicional, llamado también analógico, actualmente ofrece más problemas que soluciones a los justiciables tanto desde el punto de vista operativo como normativo. Asimismo, se aborda la noción de ciberjusticia 3.0, la cual surge a partir del uso e implementación de herramientas tecnológicas en el sistema de justicia, y cuya idea principal apela a la construcción de un modelo más eficiente y efectivo, en beneficio tanto de los operadores de justicia como de los usuarios; lo que a su vez favorece e impulsa una mejor realización de la tutela judicial efectiva.
El amparo colectivo en Guatemala: Una evolución garantista en la interpretación del presupuesto procesal de legitimación activa
Authors: Castellanos García Emanuel
Published: April 2022

ResumenEl Derecho se transforma constantemente y con ello surgen nuevas teorías, instituciones y formas de interpretación. Los jueces constitucionales tienen el deber de velar por la adecuada protección a los derechos fundamentales, debiendo realizar, para ello, una debida práctica jurisprudencial, conforme a los principios y valores constitucionales, que responda a las necesidades y problemáticas de la sociedad actual. El amparo colectivo ha sido producto de esa innovación jurisprudencial provocada como consecuencia de la necesidad de garantizar el goce y respeto de los derechos supraindividuales o difusos, para lo cual, ha existido una evolución en los criterios que se utilizan para determinar la legitimación activa en el amparo, en aras de garantizar el acceso a la justicia constitucional y procurar una mayor efectividad del amparo. El presente trabajo realiza un análisis sobre la evolución que ha tenido la interpretación del presupuesto de legitimación activa en el amparo colectivo en la jurisprudencia emanada de la Corte de Constitucionalidad de Guatemala.
Hacia la Construcción de un Código Interpretativo por la Corte de Constitucionalidad de Guatemala respecto al Derecho Humano a un Ambiente Sano
Authors: López Yuman Rosa María
Published: April 2022

La interpretación de los preceptos constitucionales que se caracterizan por su generalidad y ambigüedad, constituyen un reto permanente para las juezas y jueces constitucionales, puesto que es a ellos a quien les corresponde atribuirles sentido, labor que implica la búsqueda de un código interpretativo que se ajuste a los principios y métodos que informan la interpretación de los derechos humanos en general y en particular del derecho humano a un ambiente sano, a fin de ajustarlos a la realidad y necesidad social; sin que sea necesaria una reforma a la Ley Fundamental.
 
Abstract
The interpretation of Constitutional Precepts characterized by their generality and ambiguity, constitute a permanent challenge for Constitutional Judges, since it is up to them to give them meaning, a task that implies the search for an interpretive code that fits to the principles and methods that inform the interpretation of Human Rights in a general concept, and in particular the human right to a healthy environment, in order to adjust them to the reality and social needs; without requiring a reform of the Fundamental Law.
La Generación del Constituyente mexicano de 1916: Breves consideraciones históricas
Authors: Pineda Acevedo Humberto
Published: April 2022

Este ensayo contiene la visión política e intelectual de la generación de los diputados constituyentes que promulgaron la Constitución Política de los Estados Unidos Mexicanos de 1917, la cual continúa en vigor hasta el día de hoy. Además, expongo una estadística general de todos los constituyentes que participaron, junto con datos personales y profesionales de cada uno.
La tutela constitucional de la memoria histórica: análisis del caso del Archivo Histórico de la Policía Nacional y la figura de la “actuación inmediata de la sentencia impugnada”
Authors: Aldana Moscoso Miguel Angel
Published: April 2022

Este texto examina la situación del Archivo Histórico de la Policía Nacional -AHPN- desde la óptica jurídica, en referencia a la acción constitucional de amparo promovida por el Procurador de los Derechos Humanos, en el año 2019, contra el Ministerio de Cultura y Deportes y el Ministerio de Gobernación. En particular, se estudia el problema relativo al peligro que supone la demora de los tribunales constitucionales y las autoridades gubernamentales competentes en librar las órdenes y emprender las medidas requeridas para prevenir una situación irreparable que haga imposible restituir las cosas a su estado anterior. Para tal fin, se repasan los aspectos más relevantes de la sentencia de amparo recaída en el expediente 1281-2019 de la Corte Suprema de Justicia y, en orden a destacar una hipótesis de cumplimiento en este caso, se estudian las técnicas jurídicas que el derecho comparado ofrece para asegurar la eficacia inmediata de las sentencias constitucionales.La actuación inmediata de la sentencia impugnada es el derecho de orden procesal que confiere al actor la posibilidad de que se ejecute en forma anticipada la sentencia, independientemente que esta sea apelada, con el propósito de prevenir daños irreparables no evitables por vía del amparo provisional. SummaryThis text examines the situation of the Historical Archive of the National Police –[By its initials in Spanish AHPN]- from the legal optics, in reference to the constitutional action of amparo promoted by the Human Rights Ombudsman, in 2019, against the Ministry of Culture and Sports and the Ministry of the Interior. In particular, it is decided the problem related to the danger expected by the delay of the constitutional courts and the competent governmental authorities in issuing the orders and taking the measures required to prevent an irreparable situation that makes it impossible to restore things to their previous state. For this purpose, the most relevant aspects of the amparo sentence are read through, which are relapsed in the file 1281-2019 of the Supreme Court of Justice and, in order to highlight a hypothesis of compliance in this case, the legal techniques included in comparative law are studied  to ensure the immediate effectiveness of constitutional sentences.The immediate action of the contested sentence is the procedural law order that gives the plaintiff the possibility of having the sentence executed in advance, regardless of whether it is appealed, with the purpose of preventing irreparable damages not avoidable by an interim amparo.
Las obligaciones internacionales del Estado de Guatemala en materia de los conocimientos tradicionales de los pueblos indígenas
Authors: Urízar Montes de Oca Javier
Published: April 2022

La falta de protección legal a los conocimientos tradicionales ha perjudicado gravemente a los pueblos indígenas. Varias veces se ha reconocido la necesidad de adoptar leyes que protejan estos conocimientos de una manera culturalmente apropiada, pero a la fecha no se ha progresado en este tema. Ante la ausencia de normativa interna, ha sido el derecho internacional el que ha elaborado estándares mínimos en la materia de protección a estos conocimientos. Guatemala se encuentra obligada internacionalmente a acatar muchos de estos estándares, los cuales se analizan en el presente trabajo.
El derecho a exigir los derechos: conexiones entre el acceso a la justicia y la calificación de requisitos formales en el amparo
Authors: Calderón Cristal Ana Isabel
Published: April 2022

El trabajo apunta la existencia de normatividades que reconocen el derecho de acceso a la justicia, así como jurisprudencia que perfila el contenido y alcances de ese derecho, dentro del que se inscribe la posibilidad de acudir a un recurso sencillo y efectivo con el objeto de proteger los derechos humanos; la figura del amparo fue diseñada para tal fin en el ámbito guatemalteco. El conocimiento de esta acción se encuentra sujeta al cumplimiento de requisititos, incluidos aquellos aspectos formales. El incumplimiento de un requisito formal tiene la potencialidad de limitar el derecho de acceso a la justicia. Tal restricción se encontraría justificada en aquellos casos en los que el requisito omitido impide auténticamente la emisión de una decisión de fondo sobre el asunto. Una limitación al mencionado derecho, que sea producto de un criterio judicial que no observe el parámetro antes referido, constituiría una restricción indebida, que se traduciría en un incumplimiento, por parte del Estado, de su deber de proveer un recurso sencillo y efectivo. El análisis de la jurisprudencia de la CC da cuenta de criterios que favorecerían el cumplimiento de esta obligación.