bluuebunny/crossref_metadata_2025 huggingface dataset:
Focus on the Myocardial Hypertrophy from the Perspective of Transcriptomics and Metabolomics
Authors: Shakaryants G. A. , Kozhevnikova M. V. , Kaplunova V. Yu. , Privalova E. V. , Lishuta A. S. , Korobkova E. O. , Belenkov Yu. N.
Published: May 2020

This review presents major directions in studies of myocardial hypertrophy from the aspect of transcriptomics and metabolomics. Understanding of trigger mechanisms of myocardial hypertrophy will permit transition from basic studies to individualized clinical application of innovative technologies in the treatment of heart diseases, such as targeted therapy. At the present time, methods have been developed for diagnostics and prediction of cardiovascular diseases based on the metabolomic profiling and the evaluation of microRNA expression. Progress in studying molecular and genetic processes underlying the development of cardiovascular diseases may provide invaluable information for clinical cardiology.
Role of age, comorbidity and renin- angiotensin-aldosterone system in COVID-19. Effects of ACE inhibitors and angiotensin receptor blockers
Authors: Mareev Yu. V. , Mareev V. Yu.
Published: May 2020

The review addressed the relationship of coronavirus disease 2019 (COVID-19) with functioning of the renin-angiotensin-aldosterone axis and the causes for unfavorable prognosis depending on patients’ age and comorbidities. The authors discussed in detail potential effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists on the risk of infection and the course of COVID-2019 as well as the effect of SARS-COV2 virus on the cardiovascular system.
Epicardial and subcutenious adipose tissue adiponectin gene expression in coronary artery disease patients
Authors: Pobozheva I. A. , Razgildina N. D. , Polyakova E. A. , Panteleeva A. A. , Belyaeva O. D. , Nifontov S. E. , Galkina O. V. , Kolodina D. A. , Berkovich O. A. , Baranova E. I. , Pchelina S. N. , Miroshnikova V. V.
Published: May 2020

AimTo determine the expression of adiponectin gene (ADIPOQ) and the content of high-molecular-weight adiponectin (HMWA) in epicardial (EAT) and subcutaneous adipose tissue (SCAT) in patients with ischemic heart disease (IHD).Material and methodsPaired samples of EAT and SCAT and blood serum were withdrawn from patients with IHD after bypass surgery and 16 subjects without IHD (comparison group). Matrix RNA (mRNA) level was measured using real-time polymerase chain reaction. HMWA levels in EAT and SCAT were evaluated by Western blotting. Serum adiponectin concentration was measured immunoenzymatically. For all patients, echocardiography was performed to measure the EAT thickness; coronarography was performed to determine severity of coronary atherosclerosis.ResultsSerum adiponectin concentration was lower in IHD patients than in the comparison group (p<0.001). Levels of ADIPOO gene mRNA and HMWA in SCAT were lower in IHD patients than in the comparison group (р=0.020 and p=0.003, respectively). The HMWA level in EAT was lower with the EAT thickness of 8 mm compared to the HMWA level in IHD patients with EAT ≤8 mm (p=0.034).ConclusionThe decreased serum concentration of antiatherogenic adiponectin and the reduced expression of ADIPOQ gene in SCAT (mRNA, HMWA) are associated with IHD.
Predicting the development of adverse events in patients with acute coronary syndrome including genetics in the long-term follow-up
Authors: Shmidt E. A. , Berns S. A. , Ponasenko A. V. , Klimenkova A. V. , Tumanova S. A. , Litvinova M. N. , Barbarash O. L.
Published: May 2020

Aim To study a relationship of several factors (clinical and genetical markers) with unfavorable outcomes in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) in long-term follow-up.Material and methodsThis full-design, prospective study included 415 patients with NSTE-ACS. 266 patients were evaluated for the presence of multifocal atherosclerosis (MFA). Typing of polymorphic variants rs1041981 LTA, rs1800629 TNF, rs4986790, and rs498679 TLR4, and also rs3024491 and rs1800872 IL10 was performed. Follow-up period lasted for 67±4 months. By the end of this period, information about clinical outcomes for 396 patients became available.ResultsDuring the entire follow-up period, unfavorable outcomes were observed in 239 (57.5 %) patients with NSTE-ACS. The following clinical signs were associated with unfavorable outcomes: history of myocardial infarction, age >56 years, left ventricular ejection fraction (LV EF) ≤50 % and GRACE score ≥100, significant stenosis of brachiocephalic arteries, MFA, carriage of genotype А / А rs1041981 LTA (OR, 6.1; р=0.02) and allele А (OR, 1.9; р=0.01). According to results of a multifactorial analysis, the most significant predictors included LV EF <50 %, MFA, and carriage of genotype А / А rs1041981 LTA.ConclusionStratification of patients with NSTE-ACS into groups of high or low risk for having an unfavorable outcome within the next 6 years is possible using the prognostic model developed and presented in this study. The model includes the following signs: LV EF <50 %, MFA, and carriage of genotype А / А rs1041981 LTA.
Sarcoidosis with Cardiac Involvement and Monoclonal Gammopathy
Authors: Voronkova O. O. , Tsvetkova O. A. , Avdeev S. N. , Rogova E. F. , Abdullaeva G. B.
Published: May 2020

The article presented a clinical case of 8-year follow-up of a patient with a relatively beneficial course of pulmonary sarcoidosis and intrathoracic lymph nodes and with gradually progressing myocardial injury. A specific feature of the case was that the patient had monoclonal gammopathy, which is extremely rarely reported. Morphological signs of paraproteinemic hemoblastosis and amyloidosis were not observed. The article considered a whole complex of studies, which is required for diagnosing cardiac sarcoidosis in a specific patient and addressed the issue of monoclonal gammopathy origination.
Screening for asymptomatic heart failure with preserved ejection fraction in mongolian population at high risk
Authors: Unurjargal Ts. , Khorloo Ch. , Ulziisaikhan G. , Sodovsuren N. , Khasag A.
Published: May 2020

Objective The goals of the present study were to assess the prevalence of asymptomatic heart failure with preserved ejection fraction (HFpEF) in subjects at high risk of developing HF and to define the diagnostic accuracy of NT-pro BNP assay compared with echocardiography in this setting.Material and methods This cross-sectional study included subjects aged from 35 to 64 years, with high risk of HF, who had no clinical symptoms of HF. Risk factors of HF were detected by clinical examinations. NT-pro BNP determination was performed using immunoassay analyzer (FIA8000, Getein Bio Medical Inc, China),. The cut-off point for NT-pro BNP was 125 pg/ml. Diagnosis of HFpEF was based on criteria recommended by 2016 ESC heart failure guidelines. Diastolic dysfunction was assessed according to the algorithm proposed in the joint recommendations of the ASE/EACVI.Results 602 patients with risk factors of HF were included in the study, of which 256 (42.5 %) were males and 346 (57.5 %) females. The mean age was 51.71±8.07 years. 83 patients (13.8 %) showed elevated NT-pro BNP levels of ≥125 pg / ml. Our study has shown that NT-pro BNP concentration was positively correlating with age, both systolic and diastolic blood pressure, left ventricular mass and E / e’ ratio and negatively correlating with waist circumference, body mass index, left ventricular EF and E / A ratio in asymptomatic population. The likelihood of positive NT-pro BNP test was independently (p<0.05) associated with age, hypertension and diabetes. The diagnosis of asymptomatic HFpEF was confirmed in 12.3 % of studied population. A cutoff value of 125 pg / ml for NT-proBNP concentration showed the following diagnostic re-abilities in identifying asymptomatic HFpEF: sensitivity 85.0 %, specificity 88.6 % and area under curve 0.92 (95 % CI 0.86–0.98).Conclusion Subjects with raised NT-pro BNP level (≥125 pg/ml) were more likely to have a confirmed diagnosis of asymptomatic HFpEF after screening. In summary, in at-risk population, natriuretic peptide based screening combined with echocardiography identifies high prevalence of asymptomatic HFpEF.
‘Gand a fini par faire comme les autres’
Authors: Jonckheere Evelien
Published: May 2020

‘Gand a fini par faire comme les autres.’ The rise of the café-concert and variety theatre in late nineteenth-century Ghent’s ‘society of the spectacle’ Cafés-concerts and variety theatre have generally received only a cursory mention within the vast literature on the late nineteenth-century culture of spectacle in Europe’s major cities. This article uses Ghent as a case study to demonstrate that even in provincial towns, there was an abundance of spectacle available to the public during this era. Cafés-concerts and variety theatre played a particularly significant role and were closely interwoven with the spectacular urban renewal that took place in Ghent during the late nineteenth century. In addition, these forms of entertainment carried the seeds of the type of mass spectacle that would emerge in the twentieth century. Why, then, have the café-concert and variety theatre gone unexplored by academics for so long? In an attempt to answer this question, this article offers a means for identifying these two specific forms of spectacle in major urban centres and provincial towns in Belgium and abroad, thereby enabling a more thorough exploration of the phenomenon based on a wide range of sources. This, in turn, will allow the café-concert and variety theatre to emerge from obscurity and take their rightful place in the debate on the modern ‘society of the spectacle’.
Comparison of outcome in medical versus expectant management in unruptured tubal pregnancy with β-hCG 1000-3000 IU/L
Authors: Arshad Sidra , Andeel Sonia , Asghar Samia , Hafeez Sana , Asghar Sana , Fatima Naheed
Published: May 2020

Background: Ectopic pregnancy (EP) is an important cause of maternal morbidity as well as mortality in the 1st trimester. This study was done to compare outcome in medical versus expectant management in patients with unruptured tubal pregnancy having β-hCG 1000-3000 IU/L.Methods: In this randomized controlled trial, 82 (41 in each group) women with tubal ectopic pregnancy (TEP) having β-hCG levels between 1000-3000 IU/L and 18 to 40 years of age were enrolled. Women having non-tubal pregnancy, ruptured ectopic pregnancy, heterotopic pregnancy, hypersensitivity to methotrexate were excluded. Included women were randomly assigned to either Group-A (expectant management) or Group-B (medical management). Outcome was measured after one week and considered successful if patient had β-hCG levels negligible i.e. <10 IU/L and complete resolution on ultrasonography (absence of adnexal mass, pelvic free fluid, gestational sac).Results: Overall mean age was 30.65±6.37 years. The mean gestational age in Group-A was 7.12±2.12 weeks and 7.63±2.41 weeks in Group-B. The mean β-hCG levels in Group-A was 1984.63±515.81 IU/L and 1937.33±519.68 IU/L in Group-B. Outcome was successful in 90.24% in Group-A and 63.41% in Group-B (p-value=0.004).Conclusions: Expectant management is associated with better outcome as compared to medical management in tubal ectopic pregnancy having β-hCG between 1000-3000 IU/L.
Can seizures cause glycemic disorder in children with epilepsy? a cross-sectional study
Authors: Xuan Ngo Minh , Diem Chi Nguyen Thi , Van Anh Ton Nu
Published: May 2020

Background: Aim of this study is to investigate the serum glucose level in children with epilepsy.Methods: A cross-sectional study was conducted at Pediatric Centre of Hue Central Hospital between June 2017 and June 2019. A serum glucose level test was performed after the seizure.Results: In total, 144 patients were included in the study. Of these, the most age group was 0 - <5 years (accounted for 59.7%), followed by group 5-10 years (24.3%) and 11-15 years (16%). Female was more likely than male (52.8% vs 47.2%). The most common type was generalized epilepsy (accounted for 72.2%), and the least was un-classified epilepsy (6.3%). The blood test investigated 19 (13.2%) of patients with hyperglycemia and 1 (1.4%) with hypoglycemia.Conclusions: The present study highlights that seizure can cause glycemic disorder in children with epilepsy.
Adherence to methotrexate therapy among rheumatoid arthritis patients in Eastern India
Authors: Mukherjee Dibyendu , Naiya Suman , Chakraborty Suvajit , Chakrabarty Rahul D. , Patra Sucharita
Published: May 2020

Background: This study aims to identify adherence rate of methotrexate (MTX) therapy in rheumatoid arthritis (RA) patients of Eastern India and recognize factors contributing to treatment adherence in those patients.Methods: In this cross-sectional observational study, a total of 140 patients (17 males, 123 females; mean age 37.6±7.4 years) with pre-diagnosed RA attending the rheumatology outpatients clinic between February 2019 and January 2020 fulfilling the inclusion and exclusion criteria, were included. The patients were evaluated in terms of sociodemographic factors, clinical and medication details, disease activity score (DAS28-CRP) values and patient - doctor considerations that might contribute to treatment adherence. They filled out a series of standardised present questionnaires including the Morisky 8-item Medication Adherence Scale (MMAS-8). Data was analysed statistically and compounded.Results: Of the patients, 29 (20.7%) were adherent and 111 (79.3%) were non-adherent to medication with MTX. 65% were on MTX monotherapy and 35% on polytherapy with csDMARDs. 45.7% of the non-adherent forgot taking medication, 50.7% skipped during travel, 79.3% intentionally did not comply with strict regimen. The DAS28-CRP scores were much higher amongst non-adherent group and fewer reached remission as compared to adherent participants. Commonest reason for non-adherence being adverse drug reaction and financial constraints. Conclusions: This study showed a significantly higher adherence to MTX treatment compared to most previous studies. Adverse drug reactions, financial constraints, complex treatment regimen, long treatment duration, and frequent travel history significantly affect medication adherence in this patient population. Higher the adherence better the treatment response.
Migrasi dan Problematika Minoritas Muslim di Asia
Authors: Berutu Ali Geno Geno
Published: May 2020

Tujuan penelitian ini untuk mengetahui bagaimana migrasi muslim di Asia dan problematika yang dihadapi oleh muslim minoritas maupun imigran muslim di Asia. Penelitian ini menggunakan penelitian kualitatif dengan pendekatan studi pustaka. Data diperoleh dari buku-buku, dokumen dan jurnal serta penelitian lain yang berkaitan dengan objek penelitian. Hasil penelitian menunjukkan bahwa konflik yang berkepanjangan yang menimpa negara-negara Islam telah mendorong adanya peningkatan migrasi muslim ke Eropa dalam bentuk pencarian suaka. Disamping itu Komunitas Muslim yang minoritas ditengan-tengah agama mayoritas dalam suatunegara tertentu menunjukkan adanya penguatan politik identitas yang memicu kembali munculnya diskursus minoritas. Fenomena ini berkaitan dengan meningkatnya kesadaran kelompok-kelompok minoritas atas respon globalisasi berupa adanya hak kebebasan berkeyakinan dalam pandangan demokrasi.
Antifungal activity of eugenol on Cryptococcus neoformans biological activity and Cxt1p gene expression
Authors: Hassanpour Parviz , Shams-Ghahfarokhi Masoomeh , Razzaghi-Abyaneh Mehdi
Published: May 2020

Background and Purpose: The present study was targeted toward investigating the effects of eugenol on Cryptococcus neoformans biological activity and Cxt1p gene expression.
Materials and Methods: For the purpose of the study, the growth, urease, synergism activity, and disk diffusion of C. neoformans were assessed in eugenol-treated culture. The minimum inhibitory concentration (MIC) was determined by the Clinical and Laboratory Standards Institute M27-A3 method at a concentration range of 0.062-2 mg/mL. Subsequently, the expression of Cxt1p genes was studied at the MIC50 concentration of eugenol using real-time polymerase chain reaction.
Results: The obtained results showed that eugenol at the concentrations of 125 and 500 μg/mL resulted in 50% and 100% growth inhibition in C. neoformans, respectively. In terms of urease activity, the results showed that the addition of MIC50 of eugenol and fluconazole to urea medium reduced urease activity in C. neoformans. In the culture treated with eugenol, the inhibition zone of antifungal drugs, namely amphotericin B, itraconazole, and fluconazole, was increased to 36±0.002, 22±0.001, and 12±0.002 mm, respectively. The expression levels of Cxt1p in the eugenol-treated, fluconazole-treated, and non-treated samples were estimated at 46%, 58%, and 100%, respectively.
Conclusion: The findings of the current study revealed that eugenol could cause C. neoformans growth inhibition and reduce Cxt1p expression in this species. As the results indicated, the susceptibility of C. neoformans to fluconazole was increased when combined with eugenol.
Candida auris emergence in the Himalayan foothills: First case report from Uttarakhand, India
Authors: Meena Suneeta , Rohilla Ranjana , Kaistha Neelam , Singh Arpana , Gupta Pratima
Published: May 2020

Background and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India. Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin. Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautionsBackground and Purpose: Candida auris is a rapidly emerging fungus, which is considered globally a cause of concern for public health. This report describes the first case of C. auris fungemia from a tertiary care hospital in the hilly state of Uttarakhand in India.
Case report: The patient was a 37-year-old female who underwent a Whipple procedure for the carcinoma of the head of the pancreas. She developed fever 12 days after the operation while recovering from surgery in the hospital. Blood culture yielded C. auris which was identified by the matrix-assisted laser desorption/ionization-time of flight mass spectrometry (Bruker Daltonics, Germany). The patient was successfully treated with caspofungin.
Conclusion: In conclusion, C. auris is potentially multidrug resistant, resulting in nosocomial outbreaks and sporadic infections which can be potentially prevented when identified early by implementing contact precautions.
Predicting Depression Based on Cognitive Emotion Regulation Strategies
Authors: Dadfarnia Shekoofeh , Hadianfard Habib , Rahimi Changiz , Aflakseir Abdulaziz
Published: May 2020

Introduction: In recent years, many studies focused on emotion regulation in conceptualization, explanation, and treatment of mental disorders. Problematic patterns of emotional reactivity and regulation are prominent factors in various mental disorders, specially internalizing disorders. The present study aimed to identify the role of emotion regulation strategies in predicting depression.
Method: This descriptive –correlational research was conducted on 650 students of Yazd University selected by cluster sampling. They completed the Beck depression inventory (BDI-II) and Cognitive Emotion Regulation Strategies Questionnaire (CERQ.) Research data were analyzed in SPSS-22 by Pearson correlation coefficient and stepwise regression.
Results: A significant positive correlation was found between maladaptive emotion regulation strategies (self-blame, rumination, catastrophizing, other-blame) and depression. Adaptive emotion regulation strategies (acceptance, reorientation, plan-focus, perspective taking) were negatively correlated with depression. Results of Stepwise regression showed that self-blame, reorientation, catastrophizing, plan-focus, and other blame could explain 34% of depression variance significantly.
Conclusion: According to the results, emotion regulation strategies can be a significant factor in predicting depression; so, strengthening the adaptive cognitive emotion regulation strategies should be considered in the development and modification of treatments for depression.
Interoperability of Cloud Using Single API
Authors: Kumar P. Hari , J. Sudharshana , Kannah M Sunil
Published: May 2020

In the cloud computing model, users access services according to their requirements. Most of the people use cloud since it has low cost, high speed computing, backup and restore, mobility and unlimited flexible storage capacity. Cloud resources are hosted in large datacentres operated by companies such as Amazon, Apple, Google and Microsoft. During cloud application deployment, an application is managed over a single service. Such an approach has several short comings. One side-effect of the lack of interoperability among cloud providers is vendor lock in, which means lack of ability to migrate application components from one cloud provider to another cloud provider. If a user finds some required platforms in new service provider but the user cannot leave the current provider as the resources are present with them. This is known as vendor lock in.

To solve this issue in achieving interoperability several efforts are underway. Our project is that a user who creates a unique channel that can be used to gain the services provided by different providers. So that the user can use another vendor’s service which is not present in present vendor’s cloud. That is user can use multiple clouds having different resources using a single API without depending on their own APIs.
Biometric, Fingervein, Machine L Implementation of a Security System, Using Captured Fingervein, Applying the Concepts of Machine Learning
Authors: Elohor Oyinloye Oghenerukevwe , Folake Akinbohun , Aderonke Thompson , Bashir Korede
Published: May 2020

This work explores the field of biometric finger vein recognition – which is the identification of individuals using the unique vein patterns under their finger skins. This work also includes the implementation of an Android fingerprint biometric system using the Android Near InfraRed (NIR) module, which exists to show the similarities and differences between the two (fingervein and fingerprint) prevalent biometric features. This work thus confirms that finger vein recognition shows great promise as an accurate solution to modern society’s problem of automated personal authentication
A Review on Software-Defined Networking Distributed Controllers
Authors: Muluye Worku
Published: May 2020

A computer network is a critical issue in our day to day activity; however, today it works under various problems. Since in the current network architecture the control plane and data plane are vertically bundled on the same device. To solve this problem programmable Software-Defined Network is released. OpenFlow is a protocol that vertically separates control plane and data plane of the network devices. In SDN the controllers are the brains of the network that controls the network devices. Today’s network required successful integration of distributed controllers to make the network more consistent. SDN distributed controller is a controller that we can add or remove the controllers according to the number of devices change. Distributed controller architecture has investigated and compared the 6 recent distributed controllers by using 26 criteria. Orion is the first best controller and ONOS is the second best controller.
Evaluation of English Learning In Junior High School Samaturu Kolaka
Authors: . Suardi
Published: May 2020

Abstract

The study aims to evaluate of english learning at the Junior High School 3, Samaturu Kolaka. The method used is evaluative through the flow of the gap model (discrepancy evaluation model). Data collection through interviews, document tracing, and observation. Key Informant is the principal, teacher, and student. The results showed that: (1). The ten indicators of the principles in the preparation of lesson plan is only a contemporary-oriented indicator that is not contained in the lesson plan. This is because lesson plan is based on teaching materials and teaching materials. In addition, the lesson plan does not promote social, spiritual attitudes and only focus on English language teaching materials. Because of social and spiritual attitudes are hidden curriculum and can be applied to all subjects. Even the development of character is a program of Junior High School 3, Samaturu Kolaka. (2). All step-by-step indicators in lesson plan preparation are already loaded inside the lesson plan. But there is still an unprecedented indicator such as determining a monotonous learning strategy and not self-evaluation for the teacher to improve the strategy, and its teaching method. (3). Several indicators of lesson plan implementation have been carried out well in the classroom even though it is not maximized. This is due to preliminary activities, the teacher does not explain the importance of the material to be studied and competencies that students must master. The conclusion is related to the principles, application of steps and implementation of lesson plan in the classroom, although not maximized, but has been referring to Permendikbud no. 103 year 2014 about learning on primary education and secondary education.

 

Keywords: Evaluation, Lesson Plan, English Learning
Antifeedant Activity of Leaf Aqueous Extracts of Selected Medicinal Plants on VI Instar Larva of Helicoverpa Armigera (Hubner)
Authors: Ravi G. , Sundararajan Dr.G.
Published: May 2020

Phytochemicals, especially botanical insecticides are currently of interest because of their successful application in plant protection as biocontrol agents. Biological activity of leaf aqueous extract of ten selected medicinal plants were evaluated against the fourth-instar larvae of gram pod borer Helicoverpa armigera (H¨ubner), (Lepidoptera: Noctuidae). Antifeedant activity of leaf aqueous extracts of Abutilon indicum L., Achyranthus aspera L., Aerva lanata L., Albiziz amara (Roxb), Andrographis paniculata Ness., Cardiospermum halicacabum L., Cassia tora L., Catharanthus roseus L (G) Don., Datura metal L. and Tribulus terrestris L. were evaluated in this study. Preliminary screening after 24 h of exposure with leaf aqueous extracts of the selected plants at a concentration of 1,000 ppm exhibited significant larval mortality rate. The percentage mortality rate ranged considerably from 10.8 to 72.8. The mortality rate was observed in the decreasing order of A. paniculata > C. roseus > D. metal > A. amara > C. halicacabum > A. indicum > C. tora > T. terrestris > A. aspera >A. lanata against the larvae of H. armigera. The results imply that leaf aqueous extract of A. paniculata, C. roseus and D. metal can potentially be used as eco-friendly pest control agents against the larva of H. armigera.
Larvicidal and Antifeedant Activity of Some Plants Extracts Against the Larvae of Helicoverpa Armigera (Hubner)
Authors: Ravi G. , Dr.G.Sundararajan
Published: May 2020

In the present study, selected some plants,  namely,  Andrographis paniculata Ness., Cardiospermum halicacabum L., Cassia tora L., Catharanthus roseus L (G) Don., Datura metal L., Eupatorium riparium and Mikania  micarantha were   screened  for  their  larvicidal   and  antifeedant  activity against  the larvae of  Helicoverpa  armigera (Hubner)  under  laboratory  conditions.  The  crude  extracts  of  all  the  selected plants  demonstrated  a  dose  dependent  increase  in  bioactivity.  However  the bioactivity  of  four  plants  namely,  A.paniculata,  Cassia tora L., C.halicacabum L., and Datura metal L. was significantly higher (p ≤ 0.05) than the  control  and  extracts  of  C.roseus,  E. riparium  and  M.micarantha. Methanol  extract  of  A.paniculata  caused  highest  oral  toxicity  with  larval mortality ranging between 29.00% and 58.22% across the test concentration (0.2%, 0.4% and 1% w/v) while extract of C.tora L., demonstrated the highest feeding deterrence with reduction in larval feeding by 59.92% and 76.61%  at  0.2%  and  0.4%  respectively.  Crude  extract  of  C.halicacabum L.,  leaves demonstrated  high  oral  toxicity  and  feeding  deterrence  while extract  of D.metel showed moderate level of oral toxicity as well as feeding deterrence at the highest tested concentration. Thus  it  may  be  concluded  that  four  out  of  the  selected plants  possess insecticidal property and can be further investigated for the development of a potent natural botanical insecticide.
Measuring Conceptual Understanding, Procedural Fluency and Integrating Procedural and Conceptual Knowledge in Mathematical Problem Solving
Authors: Ho Thi Minh Phuong
Published: May 2020

The main aim of this paper is to meassure students’ mathematical proficiency on conceptual understanding and procedural fluency, and their ability of integrating procedural and conceptual knowledge in problem solving. Based on the PCK taxonomy (Ho 2018), we design a questionnaire consisting of 12 questions with 22 tasks whose content is focus on linear functions and equations. The collected data is analysed by the statistical software IBM SPSS Statistics 22. Moreover, we use the structural equation modeling (SEM) to study the correlation between these two components of mathematical proficiency and the ability of integrating procedural and conceptual knowledge in problem solving, implemented in IBM SPSS AMOS 24. The findings show that students’ mathematical proficiency on procedural fluency on linear functions and equations is higher than that of conceptual understanding, and their ability of integrating procedural and conceptual knowledge is very low. Moreover, these categories have a bi-directional relationship, in which the affection of mathematical proficiency on conceptual understanding to the ability of integrating procedural and conceptual knowledge in problem solving is stronger than on procedural fluency.
The Role of Satisfaction in Mediating Compensation and Work and Environment against Employee Retention Pt. Senyum Media Utama Jember
Authors: Wardhani Roro , Ashari Kholid , Sularso Andi , Barokah Ika
Published: May 2020

Compensation is one form of efforts to reduce the high turnover of employees. Therefore, the presence of a good compensation, the employee will keep his job. And this is one form of motivation given the company's employee retention. Not only compensation that can affect employee retention. The work environment also affect employee retention. Any organization or company seeking better working conditions and satisfactory, so that employees in the work can feel satisfied with the work he did. The low turn over to the PT. Senyum Media Utama Jember indicate high commitment of its employees, but still there are employees who do not survive or out of the company although the amount is very minimal, so it needs to be tested how the compensation, organizational commitment and the work environment influence on satisfaction and retention. The population in this study were employees of PT. Senyum Media Utama Jember as much as 150. The sample is observed is determined by purposive sampling method with the remaining number is 108. The analytical tool used is the analysis of SEM. Based on the analysis of the study results and discussion, it can be concluded that compensation, organizational commitment and the work environment influence on satisfaction and retention and satisfaction may mediate compensation, organizational commitment and work environment on employee retention. The observed sample is determined by purposive sampling method with the remaining number is 108. The analytical tool used is the analysis of SEM. Based on the analysis of the study results and discussion, it can be concluded that compensation, organizational commitment and the work environment influence on satisfaction and retention and satisfaction may mediate compensation, organizational commitment and work environment on employee retention. The observed sample is determined by purposive sampling method with the remaining number is 108. The analytical tool used is the analysis of SEM. Based on the analysis of the study results and discussion, it can be concluded that compensation, organizational commitment and the work environment influence on satisfaction and retention and satisfaction may mediate compensation, organizational commitment and work environment on employee retention.

 

Keywords: compensation, organizational commitment, work environment, satisfaction and retention
Adenofibroma mülleriano tratado con análogos de GnRH. Reporte de un caso y revisión de la literatura
Authors: Sabogal Juan Carlos , Sánchez Lilia , Ferro Jaime
Published: May 2020

Se presenta el caso de una paciente de 29 años quién acudió a nuestra consulta por sensación de masa en hipogastrio. El examen físico evidenció un útero aumentado de tamaño y la ecografía mostro la presencia de una masa intrauterina interpretada inicialmente como un mioma intracavitario por lo cual la paciente recibió  tratamiento preoperatorio con Acetato de Leuprolide, observándose desaparición de la masa. Se realizó una histerosonografía que reveló una imagen polipoide endometrial por lo que la paciente se llevo a legrado. A los tres meses de seguimiento, se observó nueva mente aumento del tamaño uterino. La revisión de la patología permitió hacer el diagnóstico de un Adenotibroma Mülleriano de lo que inicialmente se interpretó patológicamente como un pólipo endometrial. La paciente fue llevada a histeroscopia operatoria previa administración de otro ciclo de Leuprolide, con óptimo pronóstico obstétrico y permaneciendo libre de recidiva tumoral 6 meses después. Se considera que el resulta una novedosa la respuesta de éste tipo tumoral a los análogos de la GnRH y que el abordaje histeroscópico mejora la posibilidad de manejo conservador que antes era difícil.
Dengue hemorrágico y eclampsia. Reporte de un caso
Authors: Cifuentes B. Rodrigo , Abonía Orlando , Rosso Fernando
Published: May 2020

La incidencia de dengue ha aumentado dramáticamente en Cali en los últimos años, con epidemias durante 1992 y 1995. Durante 1997 se registró mas de 930 casos sospechosos y 433 serológicamente confirmados de su forma grave: el dengue hemorrágico (DH), cobró la vida de 6 personas. El brote epidémico aunado a la alta tasa de natalidad y prevalencia de preeclampsia (13.5%) en la ciudad, favorece la asociación de estas entidades en la temporada.Se presenta el caso de una primigestante de 20 años, embarazo de 36,5 semanas; con 5 días de fiebre alta, cefalea intensa, osteomialgias, gingivorragias, epistaxis, hematemesis, melenas, edemas, trombocitupenia progresiva hasta 10.000plaq/mm3 y títulos IgM ELISA (+) para dengue, quien desarrolla preeclampsia de rápida evolución a eclampsia.Se induce parto vaginal obteniendo neonato sano de 3.200grs., con choque materno durante el alumbramiento "desproporcionado" al volumen clínico de sangrado.Se propone aumentar el reporte de casos que sumen evidencias para dilucidar la hipótesis, que el DH empeora el curso de la preeclampsia; como se sospecha por los casos manejados en el Hospital Universitario del Valle (HUV) y otros reportados en la literatura.
Protocolo previo al inicio de técnicas de reproducción asistida
Authors: Madero C José Ignacio , Neira Patricio , Gaitán Pilar , Sanz Eduardo , Avila Luz Mabel , Escobar Magaly , Ruiz Jesús Alberto
Published: May 2020

La adecuada selección y estudio de las parejas que ingresan a los Programas de Reproducción Asistida garantiza los resultados en cuanto a tasas de embarazo y bebes en casa. La preparación de estas parejas consta en la mujer de un estudio cuidadoso de la función endocrina como es el conocer la reserva ovárica, el descartar patología utero-tubárica como el hidrosalpinx, la endometriosis, alteraciones del canal endocervical o de la cavidad endometrial. En el varón la presencia de alteraciones de los parámetros seminales pueden conducir desde una falla en la fertilización hasta infección en los sistemas de cultivos, y su cuidadosa evaluación optimiza los resultados. Siguiendo este protocolo estricto hemos logrado incrementar de manera importante nuestras tasas de gestación en un 13% (de 21% en 1995 y 1996 a 34% en 1997) por ciclo, lo que nos motiva a presentarlo.
Diagnóstico genético preimplantación: mirando al futuro
Authors: Giraldo Júan Luis , Habana Antonia , Serafini Paulo , Olive David
Published: May 2020

El diagnóstico genético preimplantación (PGD) es en el momento la forma más temprana de diagnóstico prenatal. En la década de los noventa su carácter experimental comienza a dar paso a su aplicación clínica. Se han reportado ya numerosos casos de nacidos vivos sometidos a PGD para la detección de enfermedades ligadas al sexo, enfermedades monogénicas y aneuploidías. Además su papel en la optimización del resultado de las técnicas de reproducción asistida está en estudio y parece promisorio, especialmente en el grupo de mujeres de mayor edad. Actualmente se utilizan la hibridización in situ fluorescente (FISH) y la reacción en cadena de polimerasa (PCR) como principales herramientas en el análisis del material genético del embrión. La obtención de este material se ha logrado mediante la biopsia de cuerpo polar, de blastómera y de trofoectodermo. En el seguimiento a corto y mediano plazo el PGD ha demostrado ser una técnica eficiente y segura, pero se carece aún de estudios con seguimiento a largo plazo que corroboren estos aspectos. Avances en el uso del PGD que faciliten su aplicación y disminuyan su costo serán responsables de una propagación en el uso de este método de diagnóstico prenatal en los próximos años.
Malformaciones uterinas y fertilización in -vitro: resultados después de histeroplastia histeroscópica
Authors: Pérez Villabona Christian Manuel , Jaimes Carvajal Hermes , Alarcón Nivia Miguel Angel , Parra Barón Claudia Patricia , Maldonado Cárdenas Harold , Blanc Bernard , Boubli Leon
Published: May 2020

OBJETIVOS DEL ESTUDIO: Determinar la efectividad del tratamiento quirúrgico endoscópico en pacientes con malformaciones uterinas sometidas a fertilización in-vitro, medida en tasa de embarazos.DISEÑO: Es un estudio de cohortes retrospectivo en un período de siete años, desde 1990 a 1997.MATERIALES Y METODOS: Para efectos del estudio se tomaron 16 pacientes con tabiques uterinos, de los cuales 9 recibieron tratamiento quirúrgico endoscópico y 7 permanecieron sin tratamiento. Se utilizaron los test de Chi Cuadrado, Chi Cuadrado con corrección de Yates y test de Fisher teniendo en cuenta el tamaño de la muestra.RESULTADOS: La edad media de las pacientes fue de 33,4 años. La tasa de embarazo fue de 44.4% en el grupo con tratamiento endoscópico quirúrgico contra un 42.8% en el grupo no tratado, observándose que la tasa de embarazos fue similar en ambos grupos sin diferencia estadísticamente significativa (p>0.05). Pero se observó que la tasa de embarazos evolutivos normales que llegaron a termino fue significativamente mayor en el grupo tratado quirúrgicamente que en el no tratado, 44.4% vs 14.2%.CONCLUSIONES: Los resultados observados nos conducen a concluir que existe una indicación para el tratamiento quirúrgico endoscópico de los tabiques uterinos antes de planear un intento de fertilización in vitro, ya que este mejora la tasa de embarazo evolutivo normal que llega a termino; al parecer por una mejoría en la capacidad y adecuación de la cavidad uterina. Así mismo, teniendo en cuenta que el factor anatómico en las malformaciones uterinas impide el normal desarrollo y evolución del embarazo; se recomienda su corrección quirúrgica endoscópica antes de toda tentativa de reproducción asistida y en general antes de una gestación natural.
Heat Transfer and Friction in a Thin Air Laminar Boundary Layer over Semi-Sphere Surface
Authors: Gorskiy V.V. , Loktionova A.G.
Published: May 2020

A qualitative solution to the problem of calculating convective heat transfer can be obtained only by numerically integrating the differential equations of the boundary layer, which is associated with overcoming a number of computational problems. Consequently, it is important to develop relatively simple, but fairly high-precision calculation methods. As a first approximation to solving this problem, we can consider the use of the effective length method. From the practical point of view, this method is characterized by satisfactory accuracy of calculating convective heat transfer, which has led to its widespread use in aeronautical design engineering. However, this method is also characterized by a relatively high complexity, although it is much lower than that in numerical integration of the differential equations of the boundary layer. The most effective approach to solving heat transfer and friction problems in engineering practice is to use simple algebraic formulae obtained on the basis of approximating the results of rigorous numerical calculations, or experimental studies. Unfortunately, there is no information in literary sources about the accuracy of these formulae under various conditions of product functioning. This problem is solved on the basis of a systematic numerical calculation of the equations of the boundary layer in the most rigorous theoretical calculation, as well as a detailed analysis of the accuracy of the obtained algebraic formulae and their literary analogues
Axisymmetric Stressed State of Uniformly Layered Space with Periodic Systems of Internal Disc-Shaped Cracks and Inclusions
Authors: Hakobyan V.N. , Amirjanyan H.A. , Kazakov K.Ye.
Published: May 2020

Using the Hankel integral transform, we construct discontinuous solutions for the problem of the axisymmetric stress state of a piecewise homogeneous, uniformly layered space, obtained by alternately connecting two heterogeneous layers of the same thickness. The space on the middle planes of the first heterogeneous layer contains a periodic system of circular disc-shaped parallel cracks, and on the middle planes of the second layer has a periodic system of circular disc-shaped parallel rigid inclusions. The determining system of equations is obtained in the form of a system of integral equations with kernels of the Weber --- Sonin type with respect to the crack extension and tangent contact stresses acting on the facial surfaces of rigid inclusions. With the help of rotation operators, the resulting determining system of equations is reduced to a system of integral equations of the second kind of Fredholm type. The equation solution is constructed by the method of mechanical quadratures. A numerical analysis was carried out and regularities were revealed in the variation of the intensity factors of rupture stresses, crack extension and contact stresses under the inclusions depending on the physical and mechanical and geometrical characteristics of the problem
Estudo de Torre de Vento: Ensaio em Túnel de Vento em Edificações Residenciais
Authors: Caroline Oliveira Silva Anne , Dimitrios Christakou Evangelos , Santos da Silva Lenildo , Alves da Silva Júnior Félix , Marcia Coutinho Gurjao Claudia
Published: May 2020

A adoção da ventilação natural em substituição à ventilação mecânica pode contribuir para a redução do consumo de energia elétrica das residências. Dentre as soluções possíveis está a utilização de torres de vento, solução arquitetônica original milenar do povo persa, para o condicionamento de ambientes internos, reduzindo o consumo de energia com ganhos significativos no quesito do conforto térmico. As torres de vento aplicadas às edificações podem funcionar como consequência da diferença de pressão do vento que incide na fachada ou devido à variação de temperatura: o ar frio entra por uma abertura, refrigerando o interior do local e empurrando o ar quente para fora do edifício. O desenvolvimento do trabalho foi dividido nas seguintes etapas metodológicas: 1) determinação dos modelos reduzidos, 2) definição dos parâmetros de ensaio, 3) programação de sensores e 4) ensaio em túnel de vento. Os resultados obtidos no túnel de vento permitiram avaliar a melhor configuração de torre de vento para cada caso, visando reduzir a temperatura interna dos ambientes. Além disso, foi possível concluir que a variação de temperatura de 0,5°C alcançada pode contribuir para a redução de consumo de energia elétrica e ao mesmo tempo preservar ou ampliar o conforto térmico dos usuários.
Análise das vazões de projeto de água fria em uma residência unifamiliar
Authors: Honorato Kelly Miranda , Campos Marcus André Siqueira
Published: May 2020

Diferente da norma vigente de água fria, ABNT NBR 5626 (1998), que aponta o uso de método empírico, o projeto de norma em elaboração recomenda o uso do método probabilístico, que permite a consideração de parâmetros como vazão e duração de uso de cada aparelho sanitário, tornando o cálculo mais preciso. Portanto, a comparação da diferença entre estes métodos se torna importante bem como compará-los com medições reais de vazões e perfis de consumo. Desta forma, realizou-se a comparação das vazões de projeto entre os dois métodos propostos no padrão brasileiro, além de métodos propostos pelo padrão europeu (EN 806-3, 2006) e o projeto de norma portuguesa substituindo o Decreto Regulamentar no. 23/95, de uma residência unifamiliar. Além disso, a partir das vazões instantâneas medidas in loco em uma residência unifamiliar, verificou-se a distribuição das vazões nos trechos do sistema de água fria. Foi possível observar que as vazões de projeto estão normalmente próximas as vazões dos aparelhos, que o método probabilístico apresentou vazões próximas as vazões medidas.
Sustentabilidade e Desempenho Térmico em Habitação de Interesse Social
Authors: Machado Jéssica de Mello , Sirtuli Bruna Perovano , Nico Rodrigues Edna Aparecida , De Alvarez Cristina Engel
Published: May 2020

Com o número crescente de investimentos em edificações de interesse social, cresce também a preocupação com o conforto térmico dos usuários, uma vez que estes imóveis estão sendo replicados em diferentes regiões do país, sem a devida preocupação com a diversidade climática e com a utilização de materiais mais adequados, especialmente quando se deseja utilizar sistemas passivos para a criação de ambientes termicamente mais confortáveis. Assim, objetivou-se comparar o nível de sustentabilidade e de desempenho térmico dos materiais comumente utilizados nas vedações verticais de habitações de interesse social multifamiliares, ventiladas naturalmente em Vitória-ES. Para esta finalidade, foram realizadas simulações computacionais com o software DesignBuilder versão 3.4.0.041, adotando-se para a análise de sustentabilidade dos materiais o ISMAS, que consiste em uma ferramenta de suporte para a seleção de materiais construtivos, pautada no conceito de sustentabilidade. Os resultados apontaram que nem sempre a utilização de materiais com classificação mais alta de sustentabilidade apresentam melhores resultados quanto ao desempenho térmico, sendo necessário analisar outros parâmetros para a melhor decisão projetual.