bluuebunny/crossref_metadata_2025 huggingface dataset:
On Modeling Murder Crimes in Nigeria
Authors: Maxwell Obubu , Udoka Chinedu Ikediuwa , Charles Ifeanyi Anabike , Chukwudike C Nwokike
Published: July 2019

This paper examines the modelling and forecasting Murder crimes using Auto-Regressive Integrated Moving Average models (ARIMA). Twenty-nine years data obtained from Nigeria Information Resource Center were used to make predictions. Among the most effective approaches for analyzing time series data is the method propounded by Box and Jenkins, the Autoregressive Integrated Moving Average (ARIMA). The augmented Dickey-Fuller test for unit root was applied to the data set to investigate for Stationarity, the data set was found to be non-stationary hence transformed using first-order differencing to make them Stationary. The Stationarities were confirmed with time series plots. Statistical analysis was performed using GRETL software package from which, ARIMA (0, 1, 0) was found to be the best and adequate model for Murder crimes. Forecasted values suggest that Murder would slightly be on the increase.
PENGARUH PROFITABILITAS, RESIKO KEUANGAN DAN PERTUMBUHAN PERUSAHAAN TERHADAP MANAJEMEN LABA PADA PERUSAHAAN KOSMETIK DAN KEPERLUAN RUMAH TANGGA YANG TERDAFTAR DI BURSA EFEK INDONESI TAHUN 2013-2017
Authors: Hasibuan Anna Nubua , Dwiarti Rina
Published: July 2019

This study aims to identify and analyze the effect of Profitability, Financial Risk and Growth on earnings management in cosmetics and household needs companies listed on the Indonesia Stock Exchange (IDX) in 2013-2017. The population used in this study are 6 companies listed on the Indonesia Stock Exchange. The process of determining the sample in this study using purposive sampling so that the number of samples obtained by 5 companies cosmetics and household needs. The type of data used in the research ii is secondary data sourced from the Indonesia Stock Exchange and the analysis technique uses multiple linear regression analysis.The results of this study indicate that partially profitability variables have a negative and not significantly effect on earnings management. Financial risk variables have a negative and not significantly effect on earnings management. The company's growth variable has a negative and not significantly effect on earnings management. The results of the study show that simultaneously the variable profitability, financial risk and company growth have no effect on earnings management.Key Points: Profitability, Financial risk and Company Growth, Profit Management
Analisis Pengaruh Faktor Fundamental Terhadap Return Saham
Authors: Insani Sheilla Nurlailly , Nurinasari Nancy , Sa’diah Laili Ayu , Radianto Denny Oktavina
Published: July 2019

This study aims to examine: (1) the effect of EPS on stock prices, (2) the effect of ROE on stock prices, (3) the effect of DER on stock prices, (4) the effect of ROA on stock prices, (5) simultaneous influence of EPS, ROE, DER, and ROA on stock prices. This research use stock returns as the dependent variable and EPS, ROE, DER, and ROA as independent variables. This study use secondary data from the annual financial statements of the property and real estate industry groups listed on the Indonesia Stock Exchange from 2013 to 2017 with using the judgment sampling method to produce 7 companies that meet the sample criteria. This study uses an associative type method with a quantitative approach. The analysis technique used is descriptive statistical analysis, classic assumption test, multicollinearity test, autocorrelation test, heteroscedasticity test, multiple linear regression analysis, and hypothesis testing. This research was conducted by retrieving data through the website www.idx.co.id which was processed based on research needs using the SPSS version 23. The results showed that the EPS, ROE, DER, and ROA ratios did not significantly influence stock returns of property and real estate listed on the Indonesia Stock Exchange.
The effect of quality of worklife and job satisfaction on organizational commitment
Authors: Pramudena Sri Marti
Published: July 2019

This study aims to determine the effect of work life quality and job satisfaction on organizational commitment. Collection research data through interviews, observation, and distribution of questionnaires to 110 respondent. The sample in this study were employees who worked at PT. Intrasari Raya Bogor. The sampling method uses simple random sampling. The research data was analyzed using the SPSS version 20. The results showed that work life quality and job satisfaction on organizational commitment had a positive and significant effect, both partially and simultaneously where t-value 4.694>t-table 1.6592 and F-value 31.054>F-table 3.08. Organizational commitment of 64.5% is influenced by other variables not included in this study. Companies are expected to be able to think of other strategies in implementing quality work life and increasing employee satisfaction so as to create strong employee commitment. Keywords: Quality of Work Life, Job Satisfaction, Organizational Commitment
The effect of own capital rentability, solvability, profitability and liquidity on dividend policy in food and beverage sub sector companies listed on Indonesia Stock Exchange (IDX)
Authors: Hadi Wartoyo , Rahayu Nuraeni
Published: July 2019

The aims of study to determine the effect of rentability of own capital, solvability, Profitability and Liquidity on dividend policy. The population of this study is all food and beverage sub-sector manufacturing companies listed on the Indonesia Stock Exchange (IDX) in 2015-2017 as many as 18 companies. While the sample is determined using the purposive sampling method. Companies that meet the criteria are only 7 companies. To analyze the data used multiple linear regression methods. The results of research, own capital rentability and current partial ratio (CR) has a negative and significant effect on the dividend payout ratio. Meanwhile, debt to equity ratio (DER) and return on assets (ROA) partially have a positive and significant effect on the dividend payout ratio. The results of the F-test show that the variable profitability of own capital rentability, solvency, profitability and liquidity simultaneously influence dividend policy. Keywords: own capital rentability, debt to equity ratio, return on asset, current ratio, dividend payout ratio.
Gap quality of employee attendance system application using technology acceptance model approach and fuzzy
Authors: Suwarman Herman Ruswan
Published: July 2019

The employee attendance system application in an educational institution occupies an important role in providing evaluation and improving performance in addition to being able to improve the transparency of employee and institutional relations. In its use, the employee attendance system must be able to accommodate the needs of its users, namely employees and staffing. This research evaluates user satisfaction over system applications using the Technology Acceptance Model approach. The evaluation was conducted by assessing the level of perception and satisfaction level of 40 users, in this case, employees. The research variable used is perceived usefulness, perceived ease of use (level of ease of use received), and user satisfaction (level of user satisfaction). Computing process was done by fuzzy methods. The results showed that some quality of the application could not meet the expectations of employees at this time. The only variable that met the performance and expectation was perceived ease. Key Words : TAM, Employee Attendance System Aplication, GAP Nad Fuzzy Method
A Sequence of Kantorovich-Type Operators on Mobile Intervals
Authors: Cappellettı Montano Mirella , Leonessa Vita
Published: July 2019

In this paper, we introduce and study a new sequence of positive linear operators, acting on both spaces of continuous functions as well as spaces of integrable functions on $[0, 1]$. We state some qualitative properties of this sequence and we prove that it is an approximation process both in $C([0, 1])$ and in $L^p([0, 1])$, also providing  some estimates of the rate of convergence. Moreover, we determine an asymptotic formula and, as an application,  we  prove that certain iterates of the operators converge, both in $C([0, 1])$ and, in some cases,  in $L^p([0, 1])$, to a limit semigroup. Finally, we show that our operators, under suitable hypotheses, perform better than  other existing ones in the literature.
ON BOREDOM IN WINTER SLEEP
Authors: Gezgın Elif , Canbolat Argun Abrek
Published: July 2019

In this work, we focus on the film Winter Sleep (2014) by Nuri Bilge Ceylan, whose works place special emphasis on various aspects of boredom. As one of the main figures in slow cinema, Ceylan, in this influential work of art, enable us to explore boredom through three main characters: Aydın (Haluk Bilginer), Nihal (Melisa Sözen) and Necla (Demet Akbağ). By taking a closer look at the film, we analyze both symbolism and the behavioral side of boredom as well as how the main characters, in our view, experience and represent distinct types of boredom. In this framework, we examine the issue of boredom and, sometimes, related despair as a result of social change. At the same time, this work partly concentrates on aspects of the socio-cultural structure of Turkey via the analysis of the main characters’ suffering.
WHO PLAYS THE HUNGER GAMES: ARTEMIS OR PERSEPHONE? THE MYTH OF PERSEPHONE IN SUZANNE COLLINS’S TRILOGY THE HUNGER GAMES
Authors: Golban Tatiana
Published: July 2019

This study focuses on Persephone myth as reflected in the popular trilogy Hunger Games by Suzanne Collins. The novelist uses the frame of this myth, with its implicit motifs of descent to the underworld and abuse, in order to reveal the anxieties of an adolescent girl, Katniss Everdeen, in her search for an authentic identity. The aim of this study is to show that Suzanne Collins also makes use of Artemis myth in her trilogy, but her eventual insistence on Persephone myth in her narrative reveals that the novelist’s purpose goes beyond the depiction of private experience of coming of age inherent in this myth, extending its function to issues related to the discovery of a social identity. The most important reason for using the mythemes of the popular myth of Persephone in her work is to represent the anxieties about societal collapse, expressed by the novelist through the images of panem et circens, hunger and predatory behaviour of eating and being eaten, which is characteristic to contemporary world. The mechanism of the cyclical death and rebirth, integral to the myth, contributes to the creation and validation of some social customs and beliefs. Therefore, Katniss Everdeen’s journey and her traumatic experience could be read as an attempt to transmit the fears of anarchic existence, the anxieties concerning politics of authority and power, but, at the same time, the hope in the emergence of a new social identity which would be built on some newly acquired and acknowledged values, such as hunger for justice, compassion and nourishment.
FAKRU’D-DEM TERİMİ VE KLASİK TÜRKÇE TIP METİNLERİNDEKİ EŞ ANLAMLILARI
Authors: Arslan Meryem
Published: July 2019

Bu çalışmada fakru’d‐dem çerçevesinde Türkçede kan eksikliği, kan yetersizliğiyle ilgilisözcüklere yer verilmiş ve fakru’d‐demle eş anlamlı sözcükler ortaya konulmaya çalışılmıştır.Konunun amacı, söz konusu metinlerde Türkçede kan eksikliği terimlerini tespit etmek, onlarınkullanıldığı dönemleri, terimlerdeki değişimleri belirlemek ve bu yolla hem Türkçe tıpterimlerine hem sözcük tarihine hem de eş anlamlı sözcüklerin oluşumuna etki eden süreçlerekatkılar sunmaktır.Çalışmanın sınırlılıkları, dönem, metin türü ve terime göre değişmektedir. Metin türü, budönemde yazılan Türkçe tıp metinleridir. Terim, kan eksikliği, kansızlık ile ilgili fakru’d‐demterimi ve onun eş anlamlılarıdır. Dönem, Batı Türkçesidir. Bu dönem de 14. ve 20. yüzyıllararasıyla sınırlandırılmıştır. Bu süreçte yazılmış 19 eser, çalışmanın verilerini toplamak içinseçilmiştir. Bu metinler aynı zamanda çalışmanın malzemesini de oluşturmaktadır.Tıp metinlerinde kansızlık, ḳan az olmaḳ; ḳan az olup bedene vefa itme‐; kıllet‐i dem; taḳlîl‐i dem ol‐;ḳanları u ruhları az ol‐; faḳru’d‐dem ve faḳîrü’d‐dem biçimleriyle karşılanmıştır. 20. yüzyıl dışındafaḳru’d‐dem ve faḳîrü’d‐dem sözcüklerinin kullanımına rastlanmamıştır. Görüldüğü gibi dahaönceki yüzyıllarda kansızlık, kan, dem biçimlerine gelen az ve ḳıllet ile oluşturulmuştamlamalarla ifade edilmiştir. Bu sözcükler, yerlerini 20. yüzyılda faḳr veya faḳîr biçiminebırakmış gibi görünmektedir.Türkçede kansızlıkla ilgili terimler burada sınırlı sayıda metin örnekleriyle incelenmiştir.Türkçe tıp metinleri sayısı düşünüldüğünde bu örneklemin çok az olduğu görülecektir.Konuyla ilgili kesin sonuçların tüm metinlerin incelenmesiyle çıkarılacağı belirtilmelidir.
Technological qualities of root crops and economic efficiency of growing sugar beet hybrids by the KWS company in the conditions of "Rasavske" Ltd. of Kaharlyk district, Kiev region
Authors: Gorodetskiy A. , Grabovskiy M.
Published: July 2019

The paper deals with the results of research on the study of the technological traits changes in foreign hybrids root crops of the KWS company sugar beet enterprises under the influence of long-term storage and their economic efficiency. The conducted researches are especially relevant due to insufficiently studied issues of changes in the technological traits of the root crops of the newest hybrids during their storage in the crutches on the field or at the sugar factory.
Estimation of new hybrids of sugar beet by regions of the Forest-steppe allows to predict the genetically determined degree of their plasticity and stability both in the yield and the quality. Hybrids with higher resistance to extreme temperatures are especially valuable.
The researches were carried out during 2014–2015 at the "Rasavske" Ltd. of Kaharlyk district, Kyiv region.
The sugar content in the root crops increased from 1.6% in the Alyona hybrid to 5.9 % in the Daria hybrid and 6.1 % in the Coryda hybrid, due to the loss of moisture during their prolonged storage. The content of soluble dry matter in the root crops increased from 1.7 % in the Alyona hybrid to 7.7 % in the Coryda hybrid for the same reason.
The conducted calculations of cell juice quality showed that long-term storage resulted in the highest growth of this indicator by 8.2 % in the Cesaria hybrid and by 7.5 % in the Acatsia hybrid. In the Alyona hybrid, the growth rate of cell juice quality was only 0.8 %, while the Corida hybrid had the quality of the previous level. In the Olesya hybrid, this indicator decreased by 1.8 % compared with the previous determination period (October 10).
The costs of growing root crops ranged from 17,859 to 20,726 UAH/ha. The highest profit was 17435 UAH/ha and the profitability level was 86.3 % for the Alyona hybrid, while the lowest economic efficiency figures were for the profit of 10,201 UAH/ha and the profitability level of 53.7 % in the Carmelite hybrid.
The highest rates of the technological traits of root crops during the long-term storage of sugar beet were determined in the Alyona hybrid. The highest yield of root crops was in the Daria hybrid – 79.8 t/ha. According to the indicators of economic efficiency the Alona hybrid was the best in terms of profit (17,435 UAH/ha) and the profitability level of 86.3 %.
Key words: sugar beet, hybrids, productivity, yield, sugar content, technological traits, profit, profitability level.
Assessment of spring wheat varieties by the productivity elements in the Forest Steppe of Ukraine
Authors: Lozinska T. , Fedoruk Yu. , Obrajyy S.
Published: July 2019

The article highlights the problems of forming the economically valuable features which affect the productivity of soft spring wheat varieties. The structural analysis data reveal that the number of spikelets in the investigated varieties of wheat ears ranged within 15.4 pcs. In the Triso variety to 20.1 pcs. in the Kharkivska 30, the rate for the variety standard was registered 16.0. The variability amplitude rate varied from 2.0 spikelets in Hordynya and Simkoda Myronivska varieties to 5.0 in the Kharkivska 30 and standart Elhiya Myronivska varieties.
The variability range of spikelets number in an ear in the Hordynya, Simkoda Myronivska and Speranza varieties and the average one in all the other varieties was revealed.
It was established that grains number in soft spring wheat varieties ranged from 41.1 grains in the Tria variety to 52.6 in the Hordynya variety, in the standard variety of Elehiya Myronivska the rate leveled 36.3. Thus, in all the studied varieties the number of grains in an ear exceeded the standard.
The variability of grains number in an ear was significant in the Speranza variety, while in other varieties as well as in the standard sort of Elehiya Myronivska it was medium.
It was shown that an ear grains weight in the varieties ranged from of 1.6 g in the Triso variety to 2.2 g in the Hordynya variety. This feature varied in the varieties by the variability range. The largest (1.1 g) it was in the the Hordynya and Speranza varieties, the smallest (0.5 g) – in the variety of Simkoda Myronivska. The variation factor proved significant variability of the trait in the Trizo and Speranza varieties and in the variety standard. All the other studied varieties were the average variability of grain weight in an ear.
It was found that all but wheat varieties of soft spring wheat had high indices of 1000 seeds and this trait variation was insignificant indicated by the variation ratewhich was below 10 %.
The correlation of crop yield and the basic economically valuable traits are analyzed; positive and negative correlations are established. It was noted that the crop yield of the studied soft spring wheat varieties correlates most closely with the number of grain in an ear (r = 0.77 ± 0.06) and the number of spikelets in an ear (r = 0.61 ± 0.07), and therefore it is necessary to pay attention to these data uppermost.
Thus, the study of economically valuable traits of modern varieties of soft spring wheat reveals different variability nature and correlation degrees which enables to define the sources of economically valuable traits in the studied varieties and to further use them in research and selection programs as valuable parent material.
Key words: spring wheat, varieties, productivity, ears number, grains number, grain weight, weight of 1000 seeds, correlation.
Peculiarities of nutrient digestibility of rations of pregnant ewes with the additional introduction of cobalt
Authors: Mykytyuk V. , Vasilenko T. , Orischuk O. , Tsap S. , Porotikova I.
Published: July 2019

The results of studies on the effect of various doses of cobalt with an optimized level of sulfur in rations of Askanian meat-and-wool ewes on digestibility of nutrients of consumed feed and digestibility of the studied mineral elements are presented.
It was established that the level of nutrient digestibility of rations was higher in ewes of the experimental groups, which, to the generally accepted norm, were additionally injected with cobalt chloride in the amount of 10 %, which was equal 0.825 mg, 20 % – 0.900 mg, and 30 % – 0.975 mg per head per day .
As a result of the conducted research, it was found that the ewes of the second experimental group differed in the highest indices of digestibility of nutrients of the ration, which increased the rate of cobalt by 10 %.
The additional introduction of 20 % and 30 % cobalt to the basic ration did not contribute to a further increase in the digestibility factors of nutrients in the body of ewes of the experimental groups.
The research has shown that the uptake of cobalt by experimental ewes increased as this element increased in the rations. Thus, 0.31 mg of cobalt was assimilated by the ewes of the second experimental group, which is 0.06 mg or 20.0 % higher compared to the control group; to the third-group of ewes by 0.07 mg or 28.0 % and to the fourth-group ewes by 0,08 mg or 32.0 % compared with analogues of the control group. However, when calculating these indicators in relative terms, it was established that the highest percentage of cobalt absorbed from that received was in the ewes of the second experimental group. Their advantage relative to the control group was 4.60 % (P <0.01), and III and IV experimental groups – 2.11 and 0.19 absolute percent.
Investigation of Microstructure and Corrosion Resistance of Dissimilar Welded Joint between 304 Stainless Steel and Pure Copper
Authors: Niknamian Sorush
Published: July 2019

Nowadays, welding of dissimilar metals has become significant. In this process, a number of parameters including but not limited to type of electrode, amount of current, preheating temperature, and welding rate, that are essential to be taken into account. For welding of dissimilar metals, various methods are exploited including shielded metal arc welding (SMAW) and gas tungsten arc welding (GTAW). The stimulus for studying welding of 304L stainless steel to pure copper originates from difficulties in joining copper parts of           water-circulating molds to their steel part. In this study, the welding is performed on plates of steel and copper using SMAW, GTAW and combined SMAW+GTAW welding methods with    EL-CuMn2, ENiCrMo-6 and ER70S-4 electrodes. In order to investigate the microstructure and corrosion resistance behavior of welds, the samples were characterized using microstructural study and polarization test. It was observed that among all four welding methods, only combined SMAW+GTAW welding process resulted in successful joint between 304L stainless steel and copper. Both obtained joints possess suitable microstructure and corrosion resistance.
Development of Writing Anecdote Text Based on Meme Comic Using Interactive Multimedia on Students in Grade 10th of MAS Islamiyah YPI Batangkuis
Authors: Nasution Tetty Ariyani , Lubis Malan , Adisaputera Abdurahman
Published: July 2019

This study aims to determine the results of development of writing anecdote text based on meme comic using interactive multimedia on students in grade 10th  of MAS Islamiyah YPI Batangkuis. Teaching materials is developed in the form of digital modules. This type of research is development research based on the development model of Borg and Gall. With the subject of the trial consisting of material experts, design experts, Indonesian language teachers, and class grade 10th MAS Islamiyah YPI Batangkuis. The results of this study indicate that (1) the validation of the material experts includes the feasibility of the contents expressed very well with a total percentage of 95.5%, the feasibility of presentation was stated to be very good with a total percentage of 90.5%, and the feasibility of the language was stated to be very good with a total percentage of 96%. (2) validation from design experts with criteria is quite good with a total percentage of 78.12%.
Efecto de la suplementación alimenticia y el Axonopus scoparius en terneros Charolais en el cantón Morona
Authors: Arias Aleman Luis , Ulloa Ramones Luis , Rojas Oviedo Luis , Condo Plaza. Luis
Published: July 2019

En la provincia Morona Santiago se ha desarrollado la ganadería de carne específicamente el Charolais el mismo que se explota en base al pasto Axonopus scoparius razón por la cual en planteó el “Efecto de la alimentación de terneros Charolais en el cantón Morona” en 30 terneros de tres meses de edad con 82.40 kg de peso en promedio, los cuales se distribuyeron en tres tratamientos (Axonopus scoparius + leche + sales minerales, Axonopus scoparius + leche + sales minerales + balanceado y Axonopus scoparius + leche + sales minerales + balanceado + probióticos) con tres repeticiones, los resultados experimentales se analizaron bajo un Diseño de Bloques Completamente al Azar y separación de medias según DMS. Durante la etapa de crecimiento la utilización de Saccharomyces cerevisiae que permitió registrar parámetros productivos, como 183,00 Kg de peso, un consumo de MS total 695,00 kg, la conversión alimenticia de 7.95 kg, y una condición corporal de 4,41, y un Beneficio / Costo de 1,08 USD, valores que superan significativamente (P<0.01) de los Tratamientos T2 y control;  de esta manera se recomienda utilizar probióticos en la alimentación de bovinos en dosis de 5 g /cabeza/día debido a que los resultados fueron satisfactorios.
Явища права: потребова інтерпретація
Authors: РАБІНОВИЧ ПЕТРО
Published: July 2019

Стаття присвячена аналізу низки фундаментальних аспектів плюралістичності праворозуміння. Зокрема, спираючись на результати унікального етимолого-правового дослідження, проведеного на початку 2000-х років на юридичному факультеті Львівського національного університету імені Івана Франка, виявлено понад десяток різноманітних соціальних явищ, стосовно яких і донині використовується термін “право”. До них належать: свобода людини, тобто простір здійснення можливостей людської поведінки (діяльності); справедливість як оцінювана щодо тих чи інших суб’єктів суспільства певна властивість суспільних явищ, зокрема людських вчинків; правила (норми) різноманітного походження стосовно людської поведінки, зокрема й звичаї і традиції; частина моралі; лише такі норми поведінки, які тими чи іншими суб’єктами вважаються справедливими; норми поведінки, встановлені саме державою, її органами чи посадовими особами; угоди (договори) учасників суспільних відносин; суспільні відносини певного виду; комунікація (дискурс) між суб’єктами; вимоги (домагання) суб’єктів щодо надання їм певних благ, цінностей, звернені до суспільства, держави чи до інших осіб; можливості задоволення людських потреб та інтересів учасників суспільних відносин; інтереси соціальних груп або усього суспільства, захищені державою чи ж іншою публічною владою; балансування (“зважування”) між собою інтересів людей та їхніх груп; почуття, переживання, емоції учасників суспільних відносин.
З’ясовуються основні причини плюралізму праворозуміння (соціальні та гносеологічні). Виявляється та спільна риса зазначених явищ, наявність якої дає змогу зацікавленим суб’єктам відображати їх одним і тим самим термінопоняттям – “право”. Такою рисою є здатність відповідних явищ сприяти задоволенню потреб та інтересів тих чи інших суб’єктів суспільства (чи то індивідуальних, чи то колективних). У підсумку резюмується, що за такого методологічного – так званого потребового – підходу правом слід вважати можливості задоволення певних людських потреб, котрі необхідні для існування і розвитку учасників суспільного життя,зумов лені досягнутим рівнем розвитку конкретно-історичного соціуму та забезпечені соціальними обов’язками його відповідних суб’єктів.
Perilaku Seksual Siswa SMA Negeri Di Kota Tanjungpinang dan Hubungannnya Dengan Perkembangan Biologis
Authors: . H Haryadi
Published: July 2019

Seksualitas menjadi sesuatu sangat menarik perhatian remaja, pada saat remaja dorongan seksualnya telah berkembang pesat. Dorongan seksual yang menggebu, apabila tidak disertai dengan seluk beluk reproduksi akan berakibat negatif. Penelitian ini bertujuan untuk mengetahui hubungan perkembangan biologis dengan perilaku seksual siswa SMA/K Negeri di Tanjungpinang.Jenis penelitian adalah kuantitatif, bersifat analitik, dengan pendekatan Cross sectional , subjek penelitian siswa SMA/K Negeri dikota Tanjungpinang kelas X dan XI yang berjumlah 568 orang. Analisis data secara univariat dan bivariat menggunakan uji Chi Square dengan nilai ά< 0,05 dan CI 95%.Berdasarkan hasil penelitian perkembangan Biologis sebahagian besar pada tahap perkembangan tidak normal (76,8%) dan 23,2% pada kreteria normal Sebagian besar siswa aktif secara seksual, dimana 55,8 % siswa pernah berfantasi seksual, 29.7% pernah melakukan onani pada laki-laki. 89,3 % Siswa SMA/K Negeri dikota Tanjungpinang memperlihatkan perilaku pacaran yang menyimpang Hasil Uji statistik nilai p < 0,05 ( 0,00) untuk Perkembangan Biologis dengan Aktifitas Seksual menunjukan hasil ada hubungan yang signifikan dan nilai p > 0,05 ( 0,286) untuk Perkembangan biologis dengan aktifitas pacaran menunjukan hasil tidak ada hubungan.  Diharapkan Semakin dini perkembangan biologis maka semakin tidak sehat perilaku seksualnya terutama aktifitas seksual yang ditampilkan siswa SMA/K Negeri di Kota Tanjungpinang. Bagi para orangtua, pendidik, konselor dan pemerhati remaja, para remaja khususnya siswa/i masih sangat perlu mendapat pendidikan seksual. Bagi remaja, perlu membentengi diri agar tidak melakukan perilaku seksual yang menyimpang dan tidak sehat dengan memahami determinannya.
EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer
Authors: Mahmud Zimam , Gomes Ana R. , Lee Hee Jin , Aimjongjun Sathid , Jiramongkol Yannasittha , Yao Shang , Zona Stefania , Alasiri Glowi , Gong Gyungyub , Yagüe Ernesto , Lam Eric W.-F.
Published: July 2019

Forkhead Box O3 (FOXO3) is a tumor suppressor whose activity is fine-tuned by post-translational modifications (PTMs). In this study, using the BT474 breast cancer cells and a recently established lapatinib resistant (BT474-LapR) cell line, we observed that higher FOXO3 and acetylated (Ac)-FOXO3 levels correlate with lapatinib sensitivity. Subsequent ectopic expression of EP300 led to an increase in acetylated-FOXO3 in sensitive but not in resistant cells. Drug sensitivity assays revealed that sensitive BT474 cells show increased lapatinib cytotoxicity upon over-expression of wild-type but not acetylation-deficient EP300. Moreover, FOXO3 recruitment to target gene promoters is associated with target gene expression and drug response in sensitive cells and the inability of FOXO3 to bind its target genes correlates with lapatinib-resistance in BT474-LapR cells. In addition, using SIRT1/6 specific siRNAs and chemical inhibitor, we also found that sirtuin 1 and -6 (SIRT1 and -6) play a part in fine-tuning FOXO3 acetylation and lapatinib sensitivity. Consistent with this, immunohistochemistry results from different breast cancer subtypes showed that high SIRT6/1 levels are associated with constitutive high FOXO3 expression which is related to FOXO3 deregulation/inactivation and poor prognosis in breast cancer patient samples. Collectively, our results suggest the involvement of FOXO3 acetylation in regulating lapatinib sensitivity of HER2-positive breast cancers.
Immunotherapy in Hodgkin Lymphoma: Present Status and Future Strategies
Authors: Vassilakopoulos Theodoros P. , Chatzidimitriou Chrysovalantou , Asimakopoulos John V. , Arapaki Maria , Tzoras Evangelos , Angelopoulou Maria K. , Konstantopoulos Kostas
Published: July 2019

Although classical Hodgkin lymphoma (cHL) is usually curable, 20–30% of the patients experience treatment failure and most of them are typically treated with salvage chemotherapy and autologous stem cell transplantation (autoSCT). However, 45–55% of that subset further relapse or progress despite intensive treatment. At the advanced stage of the disease course, recently developed immunotherapeutic approaches have provided very promising results with prolonged remissions or disease stabilization in many patients. Brentuximab vedotin (BV) has been approved for patients with relapsed/refractory cHL (rr-cHL) who have failed autoSCT, as a consolidation after autoSCT in high-risk patients, as well as for patients who are ineligible for autoSCT or multiagent chemotherapy who have failed ≥ two treatment lines. However, except of the consolidation setting, 90–95% of the patients will progress and require further treatment. In this clinical setting, immune checkpoint inhibitors (CPIs) have produced impressive results. Both nivolumab and pembrolizumab have been approved for rr-cHL after autoSCT and BV failure, while pembrolizumab has also been licensed for transplant ineligible patients after BV failure. Other CPIs, sintilimab and tislelizumab, have been successfully tested in China, albeit in less heavily pretreated populations. Recent data suggest that the efficacy of CPIs may be augmented by hypomethylating agents, such as decitabine. As a result of their success in heavily pretreated disease, BV and CPIs are moving to earlier lines of treatment. BV was recently licensed by the FDA for the first-line treatment of stage III/IV Hodgkin lymphoma (HL) in combination with AVD (only stage IV according to the European Medicines Agency (EMA)). CPIs are currently being evaluated in combination with AVD in phase II trials of first-line treatment. The impact of BV and CPIs was also investigated in the setting of second-line salvage therapy. Finally, combinations of targeted therapies are under evaluation. Based on these exciting results, it appears reasonable to predict that an improvement in survival and a potential increase in the cure rates of cHL will soon become evident.
An External Energy Independent WO3/MoCl5 Nano-Sized Catalyst for the Superior Degradation of Crystal Violet and Rhodamine B Dye
Authors: Kim Dongin , Kim Geonwoo , Bae Hyeonbin , Kim Eunwoo , Moon Byunghyun , Cheon Daho , Tarte Naresh Hiralal
Published: July 2019

In this study, the synthesis of a novel catalyst WO3/MoCl5 was carried out by the thermal method. The method gave an entirely different product compared to previous studies that doped Mo on the surface of semiconductor metal oxides. The degradation reaction of crystal violet (CV) and rhodamine B (RB) dye were done without any energy source. The results showed an incomparably superior result for degradation, with a reaction rate constant of 1.74 s−1 for 30 ppm CV, 1.08 s−1 for 30 ppm RB, and a higher value than 1 s−1 for both cases of 50 ppm dye solution. To the author’s knowledge, this catalyst has the highest reaction rate compared to other studies that targeted CV and RB, with an immense reaction rate increase of more than 100 times. Reusability of the three trials was verified, and the only process required was washing the catalyst after the reaction. One of the drawbacks of the advanced oxidation process (AOP), which has a degradation percent limit, has been solved, since 100% mineralization of the dye was available using this catalyst. FT-IR spectroscopy revealed that W-O-Mo linkage was successfully processed while Mo-Cl linkage has retained. 1H-NMR spectroscopy results confirmed that the degradation product of the dye treated by simple MoCl5 and WO3/MoCl5 was different. Deep inspection of specific regions of NMR fields gave necessary information about the degradation product using WO3/MoCl5.
Synthesis and Characterization of Silver Nanoparticles on Orthodontic Brackets: A New Alternative in the Prevention of White Spots
Authors: Jasso-Ruiz Irania , Velazquez-Enriquez Ulises , Scougall-Vilchis Rogelio José , Lara-Carrillo Edith , Toral-Rizo Victor Hugo , López-Castañares Rafael , Morales-Luckie Raúl Alberto
Published: July 2019

Silver nanoparticles (AgNPs) are used for their powerful antibacterial effect and their ability to adhere to surfaces due to their size; they are used in different areas of life, mainly in the area of health as medicine. More recently, in dentistry, the synthesis and characterization of AgNPs attracted significant attention due to their antibacterial properties. In this study, the AgNPs were synthesized using the most effective method on different orthodontic brackets (metallic and esthetic) and characterized by scanning electron microscopy/energy-dispersive spectroscopy (SEM/EDS) and transmission electron microscopy (TEM). Their antimicrobial effect was tested against the widely used standard human pathogens Staphylococcus aureus (Gram-negative) and Escherichia coli (Gram-positive). Our results showed that, via a simple chemical method, AgNPs can be synthesized on the surface of orthodontic brackets with good antimicrobial activity and the possibility of reducing dental decay, periodontal disease and white spots generated during orthodontic treatment.
Electron Traversal Times in Disordered Graphene Nanoribbons
Authors: Ridley Michael , Sentef Michael , Tuovinen Riku
Published: July 2019

Using the partition-free time-dependent Landauer–Büttiker formalism for transient current correlations, we study the traversal times taken for electrons to cross graphene nanoribbon (GNR) molecular junctions. We demonstrate electron traversal signatures that vary with disorder and orientation of the GNR. These findings can be related to operational frequencies of GNR-based devices and their consequent rational design.
Underwater Bearing-Only and Bearing-Doppler Target Tracking Based on Square Root Unscented Kalman Filter
Authors: Li Xiaohua , Zhao Chenxu , Yu Jing , Wei Wei
Published: July 2019

Underwater target tracking system can be kept covert using the bearing-only or the bearing-Doppler measurements (passive measurements), which will reduce the risk of been detected. According to the characteristics of underwater target tracking, the square root unscented Kalman filter (SRUKF) algorithm, which is based on the Bayesian theory, was applied to the underwater bearing-only and bearing-Doppler non-maneuverable target tracking problem. Aiming at the shortcomings of the unscented Kalman filter (UKF), the SRUKF uses the QR decomposition and the Cholesky factor updating, in order to avoid that the process noise covariance matrix loses its positive definiteness during the target tracking period. The SRUKF uses sigma sampling to avoid the linearization of the nonlinear bearing-only and the bearing-Doppler measurements. To ensure the target state observability in underwater target tracking, the paper uses single maneuvering observer to track the single non-maneuverable target. The simulation results show that the SRUKF has better tracking performance than the extended Kalman filter (EKF) and the UKF in tracking accuracy and stability, and the computational complexity of the SRUKF algorithm is low.
A General Framework for Fair Regression
Authors: Fitzsimons Jack , Al Ali AbdulRahman , Osborne Michael , Roberts Stephen
Published: July 2019

Fairness, through its many forms and definitions, has become an important issue facing the machine learning community. In this work, we consider how to incorporate group fairness constraints into kernel regression methods, applicable to Gaussian processes, support vector machines, neural network regression and decision tree regression. Further, we focus on examining the effect of incorporating these constraints in decision tree regression, with direct applications to random forests and boosted trees amongst other widespread popular inference techniques. We show that the order of complexity of memory and computation is preserved for such models and tightly binds the expected perturbations to the model in terms of the number of leaves of the trees. Importantly, the approach works on trained models and hence can be easily applied to models in current use and group labels are only required on training data.
Entropy? Exercices de Style
Authors: Gaudenzi Rocco
Published: July 2019

Since its inception, the concept of entropy has been known under a variety of guises and been used in an increasing number of contexts, achieving an almost rock star-like status in both the sciences and popular culture. The three most prominent “styles” which entropy has been (re)told in and which have determined its popularity are the thermodynamic, statistical and information-theoretic one, owing much to the work of Clausius, Boltzmann and Gibbs, and Shannon, respectively. In the relentless hunt for the core of the concept that spurred this development, connections with irreversibility and emergence of time, nature of probability and information emerged adding to its elusiveness as much as stimulating its proliferation and cross-contextual adoption. In this historical review, we retrace, through primary and secondary sources, the three main perspectives from which entropy has been regarded, emphasising the motivations behind each new version, their ramifications and the bridges that have been constructed to justify them. From this analysis of the foundations a number of characteristic traits of the concept emerge that underline its exceptionality as an engine of conceptual progress.
The Effect of Initial Conditions on the Laminar Burning Characteristics of Natural Gas Diluted by CO2
Authors: Han Zhiqiang , Zhu Zhennan , Wang Peng , Liang Kun , Zuo Zinong , Zeng Dongjian
Published: July 2019

The initial conditions such as temperature, pressure and dilution rate can have an effect on the laminar burning velocity of natural gas. It is acknowledged that there is an equivalent effect on the laminar burning velocity between any two initial conditions. The effects of initial temperatures (323 K–423 K), initial pressures (0.1 MPa–0.3 MPa) and dilution rate (0–16%, CO2 as diluent gas) on the laminar burning velocity and the flame instability were investigated at a series of equivalence ratios (0.7–1.2) in a constant volume chamber. A chemical kinetic simulation was also conducted to calculate the laminar burning velocity and essential radicals’ concentrations under the same initial conditions. The results show that the laminar burning velocity of natural gas increases with initial temperature but decreases with initial pressure and dilution rate. The maximum concentrations of H, O and OH increase with initial temperature but decrease with initial pressure and dilution rate. Laminar burning velocity is highly correlated with the sum of the maximum concentration of H and OH.
Heating Performance Enhancement of High Capacity PTC Heater with Modified Louver Fin for Electric Vehicles
Authors: Park Myeong Hyeon , Kim Sung Chul
Published: July 2019

Electric vehicles use positive temperature coefficient (PTC) heaters and heat pumps to warm the vehicle cabin. High-capacity PTC heaters are needed because heat pump performance decreases sharply in the winter months due to low outdoor temperatures. The weight of PTC heaters is an important heater design factor for improving the single-charge travel distance of electric vehicles. A fin shape is necessary to improve the heater’s heat transfer performance in comparison to its weight. To develop a 6 kW class high-capacity PTC heater for electric vehicles, this study presents a numerical analysis of heat flow according to a modified louver fin’s geometric shape variables and evaluates heating performance. Based on the geometric shape of an initial plate-shaped fin prototype, a numerical analysis was performed on the width, position, height, and angle to develop a modified louver fin while considering heat transfer performance and ease of manufacturing. An improved prototype was built using the developed modified louver fin, and its heating performance under standard conditions was evaluated. The improved prototype had a heating performance of 6.05 kW, an efficiency of 98.0%, a pressure drop of 18.3 Pa, and a heating density of 3.81 kW/kg. Compared to the initial prototype, its heating performance and heating density were improved by approximately 15.7%.
Enhancing the Heat Transfer in an Active Barocaloric Cooling System Using Ethylene-Glycol Based Nanofluids as Secondary Medium
Authors: Aprea Ciro , Greco Adriana , Maiorino Angelo , Masselli Claudia
Published: July 2019

Barocaloric cooling is classified as environmentally friendly because of the employment of solid-state materials as refrigerants. The reference and well-established processes are based on the active barocaloric regenerative refrigeration cycle, where the solid-state material acts both as refrigerant and regenerator; an auxiliary fluid (generally water of water/glycol mixtures) is used to transfer the heat fluxes with the final purpose of subtracting heat from the cold heat exchanger coupled with the cold cell. In this paper, we numerically investigate the effect on heat transfer of working with nanofluids as auxiliary fluids in an active barocaloric refrigerator operating with a vulcanizing rubber. The results reveal that, as a general trend, adding 10% of copper nanoparticles in the water/ethylene-glycol mixture carries to +30% as medium heat transfer enhancement.
On the Conflict between LVRT and Line Protection in LV Distribution Systems with PVs: A Current-Limitation-Based Solution
Authors: Tsimtsios Aristotelis , Voglitsis Dionisis , Perpinias Ioannis , Korkas Christos , Papanikolaou Nick
Published: July 2019

The upcoming adoption of low-voltage-ride-through requirements in low-voltage distribution systems is expected to raise significant challenges in the operation of grid-tied inverters. Typically, these inverters interconnect photovoltaic units, which are the predominant distributed energy resource in low-voltage distribution networks, under an umbrella of standards and protection schemes. As such, a challenging issue that should be considered in low-voltage distribution network applications, regards the coordination between the line protection scheme (typically consisting of a non-settable fuse) and the low-voltage-ride-through operation of photovoltaic generators. During a fault, the fuse protecting a low-voltage feeder may melt, letting the generator to continue its ride-through operation. Considering that the efficacy/speed of the anti-islanding detection is affected by ride-through requirements, this situation can lead to protracted energization of the isolated feeder after fuse melting (unintentional islanding). To address this issue, this paper proposes a fault-current-limitation based solution, which does not require any modification in the existing protection scheme. The operation principles, design, and implementation of this solution are presented, while, its effectiveness is supported by extensive simulations in a test-case low-voltage distribution system. A discussion on the presented results concludes the paper.
Cooling and Energy-Saving Performance of Different Green Wall Design: A Simulation Study of a Block
Authors: Li Jiayu , Zheng Bohong , Shen Wenquan , Xiang Yanfen , Chen Xiao , Qi Zhiyong
Published: July 2019

To mitigate the urban heat island (UHI) and release the low carbon potential of green walls, we analyzed the cooling and energy-saving performance of different green wall designs. Envi-met was applied as the main simulation tool, and a pedestrian street named Yuhou Street was selected as the study object. Four designs of walls were summarized and simulated, demonstrating the living wall system (LWS). Super soil had superiority in cooling and energy saving. Outdoor air temperature, indoor air temperature, outside wall surface temperature, and inside wall surface temperature were analyzed. Apart from the outdoor air temperature, the other three temperatures were all significantly affected by the design of green walls. Finally, energy savings in building cavities were determined. The indoor energy saving ratio of the LWS based on super soil reached 19.92%, followed by the LWS based on boxes at 15.37%, and green facades wall at 6.29%. The indoor cooling powers on this typical day showed that the cooling power of the LWS based on super soil was 8267.32 W, followed by the LWS based on boxes at 6381.57 W, and green facades wall at 2610.08 W. The results revealed the difference in cooling and energy-saving performance of different green walls in this typical hot summer area.
A Resonant Coupling Power Transfer System Using Two Driving Coils
Authors: Li Changping , Wang Bo , Huang Ruining , Yi Ying
Published: July 2019

This paper presents a resonance-based wireless power transfer (R-WPT) system using two multi-layer multi-turn inductor coils on the transmission side and a third coil on the receiver side. We theoretically characterized and optimized the system in terms of quality factor (Q factor) of the coils and power transfer efficiency (PTE). In our R-WPT prototype, the alternating currents (AC) were simultaneously applied to two transmitter coils, which, in turn, transferred power wirelessly to the secondary coil with a 3-mm radius on the receiving end. Owing to the optimization of the inductive coils, all of the coils achieved the highest Q-factor and PTE at the resonance frequency of 2.9 MHz, and the transfer distance could be extended up to 30 mm. The results show that the PTE was greater than 74% at a separation distance of 5 mm and about 38.7% at 20 mm. This is distinctly higher than that of its 2 and 3-coil counterparts using only one driving coil.