bluuebunny/crossref_metadata_2025 huggingface dataset:
Dampak Dispersion Of Ownership, Financial Distress, Dewan Pengawas, Umur Listing terhadap Pengungkapan Sukarela Bank Syariah
Authors: Alfian Barry , Handajani Lilik , Nugraha Ardana Putra I Nyoman
Published: July 2020

This study aims to look at the effect of ownership dispersion, financial distress, sharia supervisory board and age of listings on the extent of voluntary disclosure in Islamic banks registered with OJK in the 2015-2018 period. The population of the study was 14 companies of Islamic Commercial Banks and the number of samples obtained were 13 companies with an observation period of 4 years. Data analysis techniques using multiple linear regression. Statistical results show that Simultaneous that dispersion of ownership, financial distress, sharia supervisory board and age of listings have a positive and significant effect on voluntary disclosure of Islamic Commercial Banks. While partially dispersion of ownership and sharia supervisory board negative significant influence on voluntary disclosure of Islamic Commercial Banks.

Keywords: Voluntary Disclosure; Ownership Dispersion; Financial Distress; Supervisory Board; Age Of Listing.
ANALISIS POTENSI PENGELOLAAN SAMPAH BERKELANJUTAN BERBASIS MASYARAKAT DI DESA SARIBAYE NUSA TENGGARA BARAT
Authors: Ramadhanti Fati
Published: July 2020

Tourism activities are more likely to bring positive impact on the economy of the society. However, if managed poorly, the tourism activities may also bring a bad luck to the region. One of the negative impacts is the excessive unmanaged waste. The excessive waste may create problems that harm the environment and affect the society well-being. This paper aims to examine the potential of sustainable waste management practice in tourism area in Lombok, West Nusa Tenggara. This paper also intent to specifically examine the potential of community participatory aspect in sustainable waste management. This research uses Participatory Rural Appraisal (PRA) methodology to assess the primary data. Additionally, further analysis of secondary data is also added. The research is conducted in tourism area in Saribaye village, Lingsar, West Nusa Tenggara province. The results show that Saribaye village residents still lack of enviromenment awareness and the infrastructure is still far from adequate to support a sustainable management practice. However, the Saribaye village community have a high willingness to learn about the sustainable waste management practice and their current demographic structures may support the sustainable waste management development in the village.
Use of a CPD Plan Template with SMART Goals as Part of a Diabetes Pharmacotherapy Module
Authors: Dugan Byrdena DeeAnn , Hughes P.J. , Wright Sarah
Published: July 2020

Objective: To evaluate the effectiveness of a Continuing Professional Development (CPD) plan template used in Fall of 2017 on quality of SMART goal development and student quiz scores.

Innovation: The gap in time from when pharmacology is taught and when it is applied has contributed to poor student retention and performance in the diabetes pharmacotherapy course. To address this gap, the diabetes pharmacotherapy learning sequence was redesigned and included a self-assessment (pre-test), and the completion of a “CPD plan template”, which involved writing 1-3 SMART goals for each question missed on the pre-test. Following sequence completion, students took an identical post-quiz. Pre- and post- quiz scores were compared. Quality of CPD plan SMART goals was evaluated.

Key Findings: The CPD plan template was completed by 98% of students.  The majority, 62.5% of students, wrote SMART goals at the intermediate or good level, while 37.5% were evaluated as needs improvement. The average pre-quiz score was 7.4 points and average post-quiz score was 17.1 points with an average improvement of 9.8 points (p<0.0001). There was a statistically significant improvement for top 25% post-quiz scoring students who wrote “good” SMART goals compared to those who wrote goals needing improvement (p= 0.002). For students scoring in the lowest 25%, students with goals needing improvement scored higher than those with intermediate quality goals (p< 0.04).

Next Steps: It may be beneficial to introduce CPD to students sooner, as well as teach students more intentionally how to create and use SMART goals to improve learning. Finally, instructor follow up with students regarding use of their plan during a learning sequence may have additional benefit.

 

Article Type: Note
Comparison of exacerbation phenotypes among patients with severe asthma
Authors: Soenjoyo Karina Ruth , Nadkarni Nivedita , Koh Mariko Siyue
Published: July 2020

Background: Exacerbation phenotypes among patients with severe asthma have been largely characterized during stable periods. Little is known about severe asthma patients during exacerbation periods. Objective: To compare persistently frequent exacerbators
(PFE), non‐persistently frequent exacerbators (NPFE), and infrequent exacerbators (IFE) among patients with severe asthma during stable and exacerbation periods. Methods: Patients with severe asthma who were admitted for asthma exacerbations from 2011 to 2017 and
on follow up at Singapore General Hospital were recruited and categorized as PFEs (two or more exacerbations per year over 2 consecutive years), NPFEs (two or more exacerbations in 1 year only), or IFEs (fewer than two exacerbations per year over 2 consecutive years). Demographic, clinical,
and laboratory data were collected at baseline and during exacerbation periods. Results: The participants were categorized as the following: 20 PFEs, 36 NPFEs, and 57 IFEs, with no significant demographic differences. The participants as PFEs (versus NPFEs and IFEs) were
characterized by having a higher prevalence of psychiatric disorders (25% versus 8% versus 5%; p = 0.046), more comorbidities (7 versus 4 versus 2; p < 0.001), and a higher steroid burden per year (1150 versus 456 versus 350 mg; p < 0.001). The participants who were PFEs (versus IFEs)
had a higher total immunoglobulin E (IgE) level (625 versus 232 IU/mL; p = 0.046) and longer duration of admission stay (3 versus 2 days; p = 0.009). All three groups had higher blood neutrophil counts during exacerbation periods than during stable periods (p = 0.008 versus p < 0.001 versus
p = 0.004). Conclusion: The participants categorized as PFEs were characterized by comorbidities, higher steroid burden, IgE levels, and longer hospital stays. Exacerbations in the participants with severe asthma, regardless of exacerbation phenotype, were characterized
by neutrophilia. These findings provided insights into potential therapeutic strategies to reduce exacerbations in patients with severe asthma.
What is in your pantry? Entomologic anaphylaxis
Authors: Galant-Swafford Jessica , Zuraw Bruce L. , Herschbach Jack , Mahata Manjula , Mockford Edward L. , Christiansen Sandra C.
Published: July 2020

Background: The booklouse, Liposcelis bostrychophila, is a potent environmental allergen clinically associated with rhinoconjunctivitis and asthma. Despite its known infestation of grain products, anaphylaxis from ingestion of this organism has, to our knowledge, not been
previously reported. We present the case of a 44-year-old woman who developed anaphylaxis to ingested oats and rice shown to be contaminated with L. bostrychophila. Objective: The objective was to isolate a distinct antigen from L. bostrychophila implicated in a case of
unexplained anaphylaxis. Methods: In vitro studies were obtained for relevant ingested materials and aeroallergens. Skin-prick testing (SPT) was performed with standard extracts, contaminated oats, fresh oats, and crushed L. bostrychophila. Western blots were conducted
using subject and control serum to detect specific immunoglobulin E (IgE) against the grains and L. bostrychophila extract. Competitive inhibition immunoblotting was used to assess specificity of IgE binding. Results: In vitro studies and SPT were notable for positive responses
to dust mite and flour contaminated by L. bostrychophila, along with contaminated oats. Testing results for fresh oat and rice were negative. Immunoblots that used the subject's serum revealed a strongly positive band in the contaminated oat and rice extracts at 24 kD, whereas dust-mite extract
yielded a single 14-kD band. Isolated L. bostrychophila extract also yielded a 24-kD band. Competitive inhibition experiments demonstrated that the 24-kD band in the contaminated oat extract was immunologically distinct from the 14-kD dust-mite band. Conclusion: Our case
highlights the importance of considering L. bostrychophila as a potential culprit for unexplained anaphylaxis due to ingested grain products. Given the ubiquitous presence of this insect, we suspect that this may be a more common problem than previously recognized.
Miguel Aguirre, Iosu Aramburu y la profesionalización del arte contemporáneo en Lima (1997-2018)
Authors: Mitrovic Mijail
Published: July 2020

El presente artículo examina las trayectorias profesionales de los artistas Miguel Aguirre y Iosu Aramburu desde la discusión de los procesos de profesionalización del quehacer artístico en Lima entre la década de 1990 y la actualidad. Desde una perspectiva etnográfica, que aborda sus biografías y los espacios de circulación de sus obras, así como los mecanismos de validación que el campo artístico y el mercado del arte contemporáneo han activado en las últimas décadas, el autor discute los procesos económicos y discursivos que permiten comprender la transformación de la noción de “arte contemporáneo” en Lima y las dinámicas institucionales (evaluación, exhibición, comercio, etc.) que esta instala hoy en la ciudad.
Analisis Hubungan Sequential Organ Failure Assessment (Sofa) Score Dengan Mortalitas Pasien Sepsis
Authors: Iskandar Agustin , Siska Fran
Published: July 2020

Sepsis merupakan kondisi disfungsi organ mengancam nyawa yang diakibatkan oleh disregulasi sistem imun pejamu terhadap infeksi dan Sequential Organ Failure Assessment (SOFA) score merupakan suatu skoring untuk menilai kegagalan organ terkait sepsis. Peningkatan SOFA score diasosiasikan dengan outcome pasien yang lebih buruk.  Tujuan: Menganalisis korelasi SOFA score dengan mortalitas pada pasien sepsis. Metode: Desain penelitian adalah kohort prospektif yang dilakukan di RSU Dr Saiful Anwar dari Maret 2018 hingga Juni 2019. Kriteria diagnosis sepsis ditegakkan berdasarkan The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Perhitungan SOFA score dilakukan dalam 2 hari pertama perawatan pasien sepsis di rumah sakit. Analisis data dilakukan pada p < 0,05. Hasil: Didapatkan 85 pasien sepsis dengan luaran meninggal sebanyak 72,94% sedangkan 28,06% membaik. Terdapat perbedaan bermakna antara SOFA score yang meninggal dan yang hidup (p=0,015).  SOFA score dipakai untuk memprediksi kematian, didapatkan area under the curve (AUC) 0,74 (p=0,009), dengan cut off point optimum 7. Pada total SOFA score lebih tinggi dari sama dengan 7, didapatkan RR= 3.8, p=0.028. SOFA score merupakan parameter untuk menilai kegagalan organ pada pasien sepsis, dimana total SOFA score yang lebih tinggi dikaitkan dengan peningkatan risiko kematian. Simpulan: SOFA score pada kelompok yang meninggal lebih tinggi daripada yang sembuh. Pasien sepsis dengan SOFA score lebih besar sama dengan 7 memiliki risiko 3,8 kali lebih besar untuk meninggal.Kata kunci: risiko kematian, sepsis, SOFA score
Pengaruh Hormon Androgen terhadap Ekspresi Gen CD52 di Epididimis Mencit (Mus musculus)
Authors: Permatasari Silvani , Pujianto Dwi Ari , Teresa Astrid
Published: July 2020

Androgen has an important role in regulation epididymal sperm maturation  Epididymal sperm maturation is occurs via interactions between sperm and proteins secreted by epididymal genes that are specifically expressed in a region-specific manner. Mice CD52 exhibited expression in all regions in epididymis. However, the regulation of its expression by androgen is needed to be known as a gene candidate that involved in sperm maturation. Objective: This study was aimed to analyze regulation of mice CD52 expression by androgen and a bioinformatics analysis was performed to predict functional domains of CD52. Methods: bioinformatics analysis using Motif Scan. For experiment, mice divided into 5 groups. The groups were control was injected ethanol 0,1 mL/day and others groups were  3, 5, 10, and 15 day used a androgen receptor antagonist, flutamide that dilute in ethanol at a dose of 50 mg/kg/day. And then quantitative real-time RT-PCR was used to analyse expression of CD52 and it’s normalized to Beta actin. Result: CD52 contained a two potential phosphorylation sites for protein kinase C and casein kinase II, N-myristoylation, and N-glycosylation that showed CD52 is secretory protein and predict it’s attached to sperm membrane. Expression of CD52 was decrease about 93% than control. Conclusion: CD52 expression depend on androgen.Keywords:  androgen; epididymis; sperm maturation; expression of CD52
Hubungan Morfologi Plak pada Stenosis Arteri Karotis Ekstrakranial dengan Kejadian Stroke Iskemik
Authors: Sutia Dedi , Indra Syarif , Permana Hendra , Arinda Lenny , Rahmi Afriyeni Sri
Published: July 2020

Stenosis arteri ekstrakranial bermanifestasi dalam berbagai kondisi, mulai dari asimptomatik hingga stroke iskemik. Salah satu modalitas diagnostik untuk mengevaluasi gambaran stenosis tersebut adalah carotid duplex. Terdapatnya plak pada stenosis arteri ekstrakranial mempengaruhi kejadian stroke iskemik. Namun masih belum jelas hubungan antara morfologi plak pada stenosis arteri ekstrakranial dengan kejadian stroke iskemik. Tujuan: Menentukan hubungan morfologi plak pada stenosis arteri karotis ekstrakranial dengan kejadian stroke iskemik. Metode: Penelitian ini merupakan studi analitik dengan desain cross sectional yang dilakukan pada 20 orang sampel pada bulan Januari hingga September 2018 di RSUP Dr M Djamil, Padang. Kriteria inklusi adalah pasien yang telah didiagnosis stenosis arteri ekstrakranial dengan plak dari pemeriksaan carotid duplex dan kriteria eksklusi adalah pasien yang tidak datang kontrol atau tidak bisa dihubungi. Hubungan antar variable diuji dengan uji Chi-square. Hasil dianggap bermakna secara statistik jika nilai p<0,05. Hasil: Sebanyak 12 orang (60%) sampel adalah perempuan dan 8 orang (40%) adalah laki-laki. Median umur sampel adalah 56 tahun (37-71 tahun). Morfologi plak berupa plak nonulcerated sebanyak 11 orang (55%) dan plak ulcerated sebanyak 9 orang (45%). Kejadian stroke iskemik ditemukan sebanyak 9 orang (45%) dan tidak stroke sebanyak 11 orang (55%). Terdapat hubungan antara morfologi plak pada stenosis arteri ekstrakranial dengan kejadian stroke iskemik (p = 0,02); RR = 5. Simpulan: Terdapat hubungan bermakna antara morfologi plak pada stenosis arteri ekstrakranial dengan kejadian stroke iskemik.Kata Kunci: morfologi plak, stenosis arteri ekstrakranial, stroke iskemik
Faktor-Faktor yang Berhubungan dengan Penggunaan Complementary And Alternative Medicine (CAM) pada Pasien Diabetes Melitus di Puskesmas Poasia Kota Kendari
Authors: Susanti Risqi Wahyu , Indriastuti Diah
Published: July 2020

Pengetahuan masyarakat mengenai pengobatan penderita DM tak lepas dari saran penggunaan terapi komplemeter obat herbal, yang tidak jarang menjadi alternatif pemecahan masalah ketika ilmu kedokteran tak mampu memberikan solusi serta keinginan penderita maupun keluarga untuk dilibatkan secara langsung dalam proses pemilihan penyembuhan.  Tujuan: Menentukan hubungan antara penggunaan Complementary and Alternative Medicine (CAM) dengan suku, pendidikan, agama, status ekonomi, status kesehatan dan usia. Metode: Desain penelitian ini adalah cross sectional study dengan populasi seluruh pasien pasien diabetes melitus yang berada di wilayah kerja Puskesmas Poasia Kota Kendari dengan jumlah sampel yang memenuhi kriteria sebesar 40 responden. Hasil: Penelitian ini menggambarkan bahwa tidak terdapat hubungan antara penggunaan CAM dan suku, pendidikan, agama, status ekonomi, status kesehatan, sedangkan terdapat adanya hubungan antara usia dengan penggunaan CAM. Simpulan: Masyarakat untuk dapat lebih aktif menemukan informasi mengenai perawatan kesehatan berdasarkan penggunaan CAM, serta peneliti dan institusi pendidikan untuk menggunakan terapi CAM sebagai bahan pembelajaran pada konsep terapi komplementer keperawatan.Kata kunci: CAM, diabetes mellitus, komplementer, tradisional
Comprensión lectora en contextos de pobreza: un análisis desde la Visión Simple de la Lectura
Authors: Ferroni Marina , Jaichenco Virginia
Published: July 2020

La comprensión lectora resulta crucial para el desarrollo infantil. Sin embargo, en contextos de pobreza existe un alto porcentaje de niños con muy bajo desempeño en dicha habilidad. El presente trabajo analiza la relación entre el nivel lector, las habilidades de comprensión de lenguaje oral y de comprensión de textos escritos en niños que crecen en contextos de pobreza en el marco de la visión simple de la lectura. Para ello, 59 niños de quinto grado fueron divididos en dos grupos: niños con velocidad de lectura típica y niños con escasa velocidad de lectura. También se evaluaron las habilidades de comprensión lectora, comprensión de lenguaje oral, vocabulario y procesamiento morfosintáctico de ambos grupos. Los resultados señalaron que fueron las habilidades lectoras y de procesamiento sintáctico oral las que explican las diferencias en comprensión lectora. Los datos obtenidos alertan sobre la importancia de analizar las variables que impactan en la comprensión de textos escritos en poblaciones que no son las mayoritariamente descriptas en la bibliografía sobre el tema.
HUBUNGAN MANAJEMEN AKTIF KALA III DENGAN KEJADIAN PERDARAHAN POST PARTUM PRIMER DI PBM UMI SURABAYA
Authors: Widiastutik Sulenti
Published: July 2020

ABSTRAK ABSTRAK         Manajemen akif kala III merupakan suatu intervesi yang sangat penting dilakukan pada setiapasuhan persalinan normal dengan tujuan menurunkan angka kemati ibu. Sebagian besar kasus perdarahan terjadi selama persalinan kala III salah satunya seperti atonia uteri.         Dalam penelitian ini menggunakan metode analitik observasional, dengan desain penelitian ini bersifat “ cross sectional “ populasi penelitian ini sebanyak  60 ibu bersalin di PBMUmi Surabaya.Hasil penelitian menunjukkan bahwa manajemen aktif kala III dilakukan dengan sempuirna sebanyak 36 ibu  bersalin.(60%) dan ibu bersalin yang tidak mengalami perdarahan post partum primer sebanyak 33 ibu (55%) Populasi dalam penelitian ini adalah semua ibu  yang bersalin di PBM Umi Surabayadengan besar sampel sebanyak 60 ibu bersalin dengan tehnik total sampling.Dari hasil analisis data menggunakan chi square menunjukkan hasil   hitung (21,237) >  tabel (3,84) = Ho ditolak H1 diterima. Sehingga ada hubungan manajemen aktif kala III dengan kejadian perdarahan post partum primer di PBM Umi Surabaya        Upaya percepatan penurunan  AKI dapat dilakukan dengan menjamin agar setiap ibu mampu mengakses pelayanan kesehatan ibu yang berkwalitras, seperti pelayanan kesehatan ibu hamil, pertolongan persalinan oleh tenaga kesehatan terlatih, dan perawatan pasca persalinan ibu dan bayi, perawatan khusus dan rujukan jika terjadi komplikasi Kata kunci Manajemen aktif kala III, Perdarahan Post Paetum PrimerABSTRACTThe third stage of active management is a very important intervention performed in every normal childbirth care with the aim of reducing maternal mortality. Most cases of bleeding occur during the third stage of labor such as uterine atony.         In this study using observational analytic methods, the design of this study is "cross sectional" in this study population of 60 women giving birth in PBM Umi Surabaya.The results showed that the active management of the third stage was carried out with up to 36 mothers (60%) and women who did not experience primary post partum hemorrhage as many as 33 mothers (55%). a large sample of 60 mothers with total sampling technique. From the results of data analysis using chi square showed the results of X2 count (21,237)> X2 table (3.84) = Ho rejected H1 accepted. So there is an active management relationship between the third stage and the incidence of primary post partum hemorrhage at PBM Umi Surabaya        Efforts to accelerate the reduction of MMR can be done by ensuring that every mother is able to access quality maternal health services, such as health services for pregnant women, delivery assistance by trained health workers, and postpartum care for mothers and babies, special care and referrals if complications occur. Keywords Active management stage III, Primary Post Partum Bleeding
Hubungan Keteraturan Mengkonsumsi Tablet Fe Dengan Kejadian Anemia Pada Ibu Hamil Di Puskesmas Kembangbahu, Lamongan
Authors: Wasiah Asyaul
Published: July 2020

AbstrakAnemia merupakan salah satu faktor yang melatarbelakangi kematian ibu secara tidak langsung. Penyebab paling umum dari anemia pada kehamilan adalah kekurangan zat besi. Salah satu penyebab kekurangan zat besi bisa karena ketidakteraturan ibu hamil dalam mengkonsumsi tablet Fe. Padahal Sumplementasi tablet Fe atau tablet tambah darah merupakan salah satu kebijakan pemerintah dalam menanggulangi anemia gizi besi pada ibu hamil. Hal ini penting dilakukan pemeriksaan untuk anemia pada kunjungan pertama kehamilan. Bahkan jika tidak mengalami anemia pada saat kunjungan pertama, masih mungkin terjadi anemia pada kehamilan lanjutannya.Tujuan : Penelitian ini bertujuan untuk mengetahui hubungan keteraturan mengkonsumsi tablet Fe pada dengan kejadian anemia pada ibu hamil di Puskesmas Kembangbahu, Lamongan. Metode Penelitian: Penelitian ini menggunakan desain penelitian Observasional analitik dengan pendekatan Cross sectional, metode pengambilan sampel menggunakan Simple Random Sampling dan pada analisa univariat yang digunakan adalah Kendall Tau. Jumlah responden sebanyak 63 responden dan alat yang digunakan yaitu kuesioner.Simpulan hasil penelitian adalah Ada hubungan antara keteraturan ibu hamil mengkonsumsi tablet Fe dengan kejadian anemia. Hal ini diperoleh dari hasil uji statistik bahwa nilai significancy p sebesar 0,004 yang berarti H1 diterima dan H0 ditolak dan nilai koefisien kontingensi 0,339. Diharapkan ibu hamil patuh mengkonsumsi tablet Fe, melihat pentingnya mengkonsumsi tablet Fe selama kehamilan serta akibat yang dapat ditimbulkan bila tidak dikonsumsi secara teratur2. Kata kunci: tablet Fe, Anemia, Ibu hamil
Communicating the potency of tourism: Study case of Wisata Bahari Lamongan
Authors: Khitam Muhammad Chusnul , Suaedi Falih , Asmorowati Sulikah
Published: July 2020

This study aimed to determine the negotiation model and system of tourism partnership between the local government and the private sector to develop the “Wisata Bahari Lamongan” (WBL). This research used the qualitative method and negotiation theory part of public diplomacy. This research found that the negotiation and collaboration system used was the Public-Private partnership model with a built/operate/transfer (BOT) system. The private sector was allowed to build tourism facilities according to specified specifications. Then, the facility was built and operated by a private party for 25 years. After the period ended, Wisata Bahari Lamongan ownership was transferred to the local government.
Dying as a king: The Seleucids in the Fragments of Porphyry Transmitted by Eusebius' Chronicon Morire da re: I Seleucidi nei frammenti di Porfirio trasmessi dal Chronicon di Eusebio
Authors: Brillante Sergio
Published: July 2020

The aim of this paper is to analyze a fragment by Porphyry concerning Seleucid history and transmitted by Eusebius of Caesarea's Chronicon. A short introduction on this work (par. 1) will be followed by a defense of the authorship of the fragment as Porphyrian, and by a cautious
suggestion to assign it to the Contra Christianos (par. 2). In the last section, the fragment will be examined at length and its ideological background will be highlighted. In particular, the account of Seleucid kings' deaths shows that Porphyry turned to sources favorable to that dynasty.
A critical voice seems to raise only when the author recounts of Demetrius I and of his descendants.
Optimasi Blending Pertalite dengan Komponen Reformate di PT. XYZ Balikpapan
Authors: Megawati Eka , Warsa I Ketut , Setiawan Mochammad Wahyu
Published: July 2020

Penelitian ini bertujuan untuk perbaikan produk Pertalite menggunakan komponen Reformat agar memenuhi spesifikasi yang telah ditetapkan oleh Dirjen Migas. Metode blending merupakan teknik pengumpulan data yang berupa perhitungan optimasi blending pertalite dengan penambahan komponen reformate menggunakan rumus trial & error/coba-coba. Beberapa rumusan perhitungan blending yang di pakai untuk membuat Pertalite dari komponen-komponennya adalah: Blending, Distilasi, Octane Number dan RPV. Berdasarkan perhitungan hasil distilasi 10% sebesar 68,88 oC, 50% sebesar 106,94 oC, FBP 201,91 oC, Reid Vapour Pressure (RVP) sebesar 48,78 Kpa, density at 15 oC sebesar 762,60 Kg/liter, dan ON diperoleh angka sebesar 90. Berdasarkan hasil analisa Perhitungan Optimasi blending pertalite ON 89,5 dengan Reformat menggunakan rumus trial & error/coba-coba, pencampuran titik blending telah memenuhi spesifikasi Distilasi, RVP dan Density. Pertalite ON 90 diperoleh dari percampuran pertalite ON 89,5 sebanyak 5320 m3 dengan Reformat sebanyak 415,625 m3.
Studi Awal Pembuatan Membran Chitosan-Silica Based dari Berbagai Limbah
Authors: Setiawan Felix Arie , Arimbawa I Made , Putri Navisa Ayudia , Fachri Boy Arief
Published: July 2020

Jember memiliki potensi perikanan terutama udang sebagai sumber kitin yang merupakan dasar pembuatan kitosan. Kitosan berasal dari limbah kulit udang yang dicampur dengan limbah lain yaitu padatan silika dari Pembangkit Listrik Panas Bumi dan fly ash dari Pembangkit Listrik Tenaga Uap untuk menghasilkan membran yang dapat digunakan dalam filtrasi logam berat dalam air. Membran tanpa silika dibuat sebagai negative control dan dengan silika murni sebagai positive control. Membran kitosan dibuat dengan cara mencampurkan 1,0 gram kitosan dalam 100 mL larutan asam asetat 2% v/v dan 0,8 gram senyawa silika serta 0,5 gram polyethylene glycol. Membran yang telah dibuat diuji untuk menyaring larutan yang mengandung logam berat Cu dan Pb. Konsentratsi optimum dari Cu dan Pb dalam badan cairan dapat dikurangi sebesar 87% dan 80% menggunakan membran kitosan-silika.
Comparison of Clinically Approved Molecules on SARS-CoV-2 Drug Target Proteins: A Molecular Docking Study
Authors: Cubuk Hasan , Ozbil Mehmet
Published: July 2020

The new type of coronavirus, SARS-CoV-2 has affected more than 6.3 million people worldwide. Since the first day the virus has been spotted in Wuhan, China, there are numerous drug design studies conducted all over the globe. Most of these studies target the receptor-binding domain of spike protein of SASR-CoV-2, which is known to bind human ACE2 receptor and SARS-CoV-2 main protease, vital for the virus’ replication. However, there might be a third target, human furin protease, which cleaves the virus’ S1-S2 domains taking active role in its entry into the host cell. In this study we docked five clinically used drug molecules, favipiravir, hydroxychloroquine, remdesivir, lopinavir, and ritonavir onto three target proteins, receptor binding domain of SARS-CoV-2 spike protein, SARS-CoV-2 main protease, and human furin protease. Results of molecular docking simulations revealed that human furin protease might be targeted against COVID-19. Remdesivir, a nucleic acid derivative, strongly bound to the active site of this protease, suggesting this molecule can be used as a template for designing novel furin protease inhibitorsto fight with the disease. Protein-drug interactions revealed at the molecular level in this study can pave the way for better drug design for each specific target.
HT-SuMD: Making Molecular Dynamics Simulations Suitable for Fragment-Based Screening. a Comparative Study with NMR
Authors: Ferrari Francesca , Bissaro Maicol , Fabbian Simone , de Almeida Roger Jessica , Mammi Stefano , Moro Stefano , Bellanda Massimo , Sturlese Mattia
Published: July 2020

In this manuscript, for the first time, we presented a fragment library and we validated its performance by comparison with a well-established technique for fragment screening as solution NMR. We were able to screen 400 different fragments producing a total of 1200 independent fragment-protein recognition pathways. As far as we know, this represents the largest screening based on Molecular dynamics ever reported. Our simulations successfully detected the true binders in the library in a prospective study, showing a notable agreement with a state-of-art screening we performed by NMR on the same dataset.
Photocatalytic Hydrophosphination with Air-Stable and Commercially Available Bis(acetylacetonato)copper(II) (Cu(acac)2)
Authors: Dannenberg Steven , Waterman Rory
Published: July 2020

Bis(acetylacetonato)copper(II) (Cu(acac)2, 1), is active for the hydrophosphination of alkenes and alkynes with primary and secondary phosphines. Under thermal conditions, the activity of 1 is comparable to some of the best literature catalysts, but 1 is unique in that set possessing air- and water-stability. However, under ambient temperature irradiation centered at 360 nm, the conversions are remarkable with some reactions complete in minutes and several rarely reported unactivated substrates achieving high conversions within hours. The photocatalytic conditions are critical, and comparison to literature catalysts has been made in which 1 demonstrates superior activity. Initial mechanistic work does not suggest a radical mechanism rather the formation of a copper(I) active species. Hammett analysis indicates that depending on the substrate, either a nucleophilic or insertion-based mechanism may be at work. The enhanced reactivity provided by light also appears to be generalizable to other copper(I) compounds under irradiation, representing a broader phenomenon in metal catalyzed P–C bond formation. This simple, bench-stable, and inexpensive catalyst is highly effective, placing hydrophosphination in the hands of many more synthetic chemists.
Quantification of High Temperature Transition Al2O3 and Their Phase Transformations
Authors: Kovarik Libor , Bowden Mark , Andersen Amity , Jaegers Nicholas R. , Washton Nancy , Szanyi János
Published: July 2020

High temperature exposure of gamma-Al2O3 can lead to a series of polymorphic transformations, including the formation of delta-Al2O3 and theta-Al2O3. Quantification of the microstructure in the delta/theta-Al2O3 formation range represents a formidable challenge as both phases accommodate a high degree of structural disorder. In this work, we explore the use of XRD recursive stacking formalism for quantification of high temperature transition aluminas. We formulate the recursive stacking methodology for modelling of disorder in delta-Al2O3 and twinning in theta-Al2O3 and show that explicitly accounting for the disorder is necessary to reliably model the XRD patterns of high temperature transition alumina. In the second part, we use the recursive stacking approach to study phase transformation during high temperature (1050 ºC) treatment. We show that the two different intergrowth modes of delta-Al2O3 have different transformation characteristics, and that a significant portion of delta-Al2O3 is stabilized with theta-Al2O3 even after prolonged high-temperature exposures. In discussions, we outline the limitation of the current XRD approach and discuss a possible multimodal XRD and NMR approach which can improve analysis of complex transition aluminas.
A Database Framework for Rapid Screening of Structure-Function Relationships in PFAS Chemistry
Authors: Su An , Rajan Krishna
Published: July 2020

This paper describes a database framework that enables one to rapidly explore systematics in structure-function relationships associated with new and emerging PFAS chemistries. The data infrastructure maps high dimensional information associated with SMILES encoding of molecular structure with activity/property data. This ‘PFAS-Map’ serves as a 3-dimensional unsupervised visualization learning tool to automatically classify new PFAS chemistries into current well-established criteria for PFAS classification. We provide examples on how the PFAS-Map can be utilized, including the ability to predict and estimate yet unmeasured fundamental physical properties of PFAS chemistries, uncovering hierarchical characteristics in existing classification schemes and the fusion of data from diverse sources.
Investigation of antiulcer activity of Pergularia extensa Linn
Authors: Pavani C H
Published: July 2020

This study was based on determination of the antiulcer activity from methanol extract was prepared by using barks of pergularia extensa linn.. Priliminary investigations showed presence of saponins, terpenes, cardiac glycosides, alkaloids and sterols. Based on OECD-423 Guidelines, the pharmacology and acute oral toxicity studies were conducted by using methanolic extract. Ulcer development was prevented by Tannins because of their vasoconstriction effects and due to protein precipitation. Similarly, the Methanolic extract of Pergularia extensa Linn shows triterpenoids and saponins. The phytoconstituents are present in the extract and these could be possible agents which are involved in order to prevent gastric lesions induced by aspirin. When compared to ulcerative control groups, this Pergularia extensa Linn., shows a dose dependent curative ratio. The extracts exhibited an inhibition percentage of 27.18, 45.47 and 61.28 at doses of 100, 200 and 400mg/kg doses respectively.
Comparison of in-vitro anti-inflammatory activity of various extracts of Solanum tuberosum
Authors: Magesh M
Published: July 2020

Medicinal plants are vital and have been used in traditional systems of medicine of India. Their importance is not restricted to direct usage in the treatment. Still, also their chemical constituents were used as leads for many potential synthetic drugs that are drugs of choice to treat dangerous diseases. Inflammations are the significant sources of diseases and deteriorations in the body that result in body pains, and brain damages too. The inflammation is a body responding to the stimulus that causes harm to the body. Solanum tuberosum is a common staple crop available in the kitchen of every house and is used a food. It had a rich source of starch and anthocyanins. Even though it is used as a food crop, the pharmacological activities of potato had been investigated as IBD (Inflammatory Bowel Disease), various cancers, Hyperlipidemia and growing cardiovascular complications etc. the potato has been selected for the current study to compare the anti-inflammatory activity of various extracts of the plant. The action of the extracts was tested using two methods invivo using albino rats. The extracts showed a better movement, but when compared to the standard, they are less potent. But in consideration of the side effects and toxicity of standard synthetic drug the anti-inflammatory action can be compromised a bit to give a safe and potent activity
The Effect of Service Quality and Price Strategy on Customer Satisfaction through Purchasing Decisions as an Intervening variable In 212 Mart Gowa, South Sulawesi Province
Authors: Nurul Afra , Payangan Otto Randa , Ismail Muhammad
Published: July 2020

Along with the development of increasingly modern times, this has caused a lot of competition in the business world, including retail business. Every businessman needs to pay attention to the factors that influence customer purchasing decisions. The research objective is to determine the effect of service quality and pricing strategies on purchasing decisions, determine the effect of service quality and pricing strategies on customer satisfaction, determine the effect of purchasing decisions on customer satisfaction, to determine the effect of service quality and price strategies on customer satisfaction through purchasing decisions at 212 Mart Gowa The population in this study were all consumers who shop at 212 Mart Gowa determined as many as 100 respondents. Data collection techniques through observation, interviews, and questionnaires. While the data analysis technique uses validity and reliability, path analysis, hypothesis testing, and coefficient of determination. The results of the study found that service quality has a positive but not significant effect on purchasing decisions, price strategy has a positive effect but is not significant on purchasing decisions, service quality has a positive and significant effect on customer satisfaction, price strategy has a positive and significant effect on customer satisfaction, purchasing decisions have a positive effect and significant on customer satisfaction, service quality has a positive but not significant effect on customer satisfaction through purchasing decisions, and the price strategy has a positive but not significant effect on customer satisfaction through purchasing decisions on 212 Mart Gowa.
The Effect of Work Motivation, Work Environment, and Work Discipline on Employees’ Performance Of Samsat Office, Makassar
Authors: Firmansyah Ade , Maupa Haris , Taba Idrus , Hardiyono Hardiyono
Published: July 2020

The most important aspect of being an employee of performance within an organization, because it is becoming one of the determining factors in the achievement of the vision and mission of the organization. This study aimed to examine the effect of work motivation, work environment, work discipline on employees’ performance. This research was conducted in SAMSAT Office of Makassar City for two months. The types of data were quantitative data and the sources of data were primary and secondary data. The populations were all employees of SAMSAT Office of Makassar City consisting of 75 people (the police and the civil officials 51 people, dispenda 21 people, and jasaharja 3 people). All populations were taken as samples (census sampling method). They were obtained through survey. They were analyzed using validity test, reliability test, descriptive analysis, and multiple linear regression analysis. The results of the research indicate that work motivation, work environment, and work discipline have a positive and significant effect on employees’ performance. All researches hypotheses are accepted. This indicates that the increase of work motivation, work environment, and work discipline can improve employees’ performance.
Investor Reactions on Emitents Who Published Corporate Sukuk Listed in Indonesia Stock Exchange
Authors: Damang Kasman , Troena Eka Afnan , Ali Muhammad , Habbe Abdul Hamid
Published: July 2020

This study applied an event study approach  (event study).  The event tested the announcement of Sukuk emissions and market reactions as indicated by the existence of a significant Abnormal Return on the date of Sukuk emissions and it changed within the activity of Stock Trader of the Corporation Sukuk Issuer. Observation period between 2009-2018, there was 129 Sukuk emissions in Indonesia Stock Exchange. The number of samples taken was 26 emissions of Sukuk which make emissions from 12 issuers that met the set criteria. Data were analyzed using descriptive statistical analysis, independent t-test, t-paired test, and regression analysis.  Furthermore, the data were processed using IBM SPSS for Windows Software. The results showed that there was a difference in Average Abnormal Return (AAR) before and after the announcement of Sukuk emissions. However, the average value of the difference was not statistically significant. There was a positive market reaction on Average Abnormal Return (AAR) before the announcement of Sukuk emissions. There was a positive market reaction on Average Abnormal Return (AAR) after the announcement of Sukuk emissions. There were differences in the Average Trading Volume Activity (ATVA) before and after the announcement of Sukuk emissions. However, the average value of the difference was not statistically significant. There was a significant market reaction on Average Trading Volume Activity (ATVA) before the announcement of Sukuk emissions. There was a significant market reaction of Average Trading Volume Activity (ATVA) after the announcement of Sukuk emissions. Furthermore, this study also found that Sukuk to Equity Ratio (SER) had a positive effect, but not significantly on the level of  Return on Assets (ROA), Return on Equity (ROE), and Earning per Share (EPS), but it was not significant. These insignificant effects of  SER  on the issuer's  ROA,  ROE  and  EPS were caused by the relatively small proportion of Sukuk value compared to the value of assets and company equity.
Metabolic and microbial responses to the complexation of manuka honey with α-cyclodextrin after simulated gastrointestinal digestion and fermentation
Authors: Parkar SG , Jobsis CMH , Herath TD , Stoklosinski HM , van Klink JW , Sansom CE , Sims Ian , Hedderley DI
Published: July 2020

© 2017 Manuka honey (MH), α-cyclodextrin (C) and a formulation containing these two components (MH + C) were subjected to simulated gastrointestinal digestion followed by fermentation with human faecal microbiota. The honey monosaccharides, glucose and fructose were 9- and 3-fold higher respectively in the digesta of MH + C compared with MH. Methylglyoxal (MGO), characteristic of MH was absent after gastric digestion. The precursor of MGO, 1,3-dihydroxyacetone was found to be at a higher concentration in MH + C, compared with MH, after digestion. The MH + C fermenta were more acidic (pH 4.6, p < 0.05), with a higher lactate concentration (p < 0.005). Compared with water control, MH + C fermenta significantly inhibited Salmonella enterica Typhimurium (p = 0.041) and enhanced Lactobacillus reuteri (p = 0.016). These findings suggest that complexation with α-cyclodextrin protects some MH components during digestion. This increases the availability of substrates to faecal bacteria resulting in the generation of metabolites that favour gut health.
Structure of a shear-thickening polysaccharide extracted from the New Zealand black tree fern, Cyathea medullaris
Authors: Wee M , Mastrangelo M , Carnachan Susan , Sims Ian , Goh K
Published: July 2020

A shear-thickening water-soluble polysaccharide was purified from mucilage extracted from the fronds of the New Zealand black tree fern (Cyathea medullaris or 'mamaku' in Māori) and its structure characterised. Constituent sugar analysis by three complementary methods, combined with linkage analysis (of carboxyl reduced samples) and 1H and 13C nuclear magnetic resonance spectroscopy (NMR) revealed a glucuronomannan comprising a backbone of 4-linked methylesterified glucopyranosyl uronic acid and 2-linked mannopyranosyl residues, branched at O-3 of 45% and at both O-3 and O-4 of 53% of the mannopyranosyl residues with side chains likely comprising terminal xylopyranosyl, terminal galactopyranosyl, non-methylesterified terminal glucopyranosyl uronic acid and 3-linked glucopyranosyl uronic acid residues. The weight-average molecular weight of the purified polysaccharide was ~1.9×106Da as determined by size-exclusion chromatography coupled with multi-angle laser light scattering (SEC-MALLS). The distinctive rheological properties of this polysaccharide are discussed in relation to its structure. © 2014 Elsevier B.V.
Structural characterisation of xyloglucan secreted by suspension-cultured cells of Nicotiana plumbaginifolia
Authors: Sims Ian , Munro SLA , Currie G , Craik D , Bacic A
Published: July 2020

Linkage analysis of a xyloglucan from the extracellular medium of suspension cultures of Nicotiana plumbaginifolia showed mostly 4-Glcp and 4,6-Glcp, terminal Xylp and 2-Xylp, and terminal Araf, along with ~10% (w/w) O-acetyl groups, equivalent to ~ 0.28 mol acetyl per mol of glycosyl residue. Methylation with methyl trifluoromethanesulfonate under neutral conditions, followed by re-methylation with CD3I under basic conditions, and conversion into partially methylated alditol acetates showed that O-acetyl groups were primarily attached to C-6 of ~44% of the 4-Glcp backbone not substituted with Xylp residues and to C-5 of ~15% of the terminal Araf residues. These positions of the O-acetyl groups were confirmed by 1H-NMR. Oligosaccharides generated by digestion of native xyloglucan with endo-(1 → 4)-β-glucanase were separated by a combination of gel-filtration chromatography and anion-exchange HPLC, and analysed by glycosyl linkage analysis and by electrospray ionisation-mass spectrometry (ESI-MS). The major oligosaccharide subunits were Glc4Xyl2 and Glc5Xyl2, of which 50-60% are substituted with one terminal Araf residue attached to O-2 of a Xylp residue, and a further 20-25% are substituted with two terminal Araf residues attached to O-2 of the Xylp residues. ESI-MS showed that many of the oligosaccharide subunits carried one, two and, occasionally three O-acetyl groups.
Estágio de pós-doutorado em terras lusitanas: relato de experiência
Authors: Machado Claudia
Published: July 2020

Este artigo apresenta relato de experiência de estágio de pós-doutorado realizado em Portugal, na Universidade de Aveiro. Durante a realização do estágio, foram desenvolvidas várias atividades que fizeram desse momento um proveitoso caminho, que abriu os horizontes, aguçou a curiosidadecientífica e o compromisso com a pesquisa. O foco do trabalho de pesquisa desenvolvido durante o estágio foi o uso das redes sociais por estudantes de nível superior. Conclui-se pelo estímulo a mais pesquisadores desenvolverem estágios em instituições de ensino portuguesas.
Juventude pescadora: questões conceituais, de classe e o processo de construção do ser jovem
Authors: Alves Rodrigues Adenil , Pereira da Silva Gilmar , Martins Egidio
Published: July 2020

A partir de um recorte de classe, buscou-se discutir como a juventude está sendo vista por um conjunto de sujeitos que produzem suas existências por meio do trabalho da pesca. Tomando como referência o materialismo histórico-dialético, concluiu-se que os jovens pescadores de Cametá-PA vivem o momento de ser jovem não de maneira plena e socialmente realizável, e sim, truncada, e, não raras vezes, protelada. Contudo, também resistem e lutam contra as negações que são por eles vividas, mostrando,assim, uma clara compreensão da realidade contraditória da qual fazem parte.
O trabalho no século XXI e a Base Nacional Comum Curricular
Authors: Aparecido Cordão Francisco
Published: July 2020

Francisco Aparecido Cordão entrevista Mozart Neves Ramos
Barriers to the maturity of student’s career planning as millennial generation
Authors: Nurlela Nurlela , Surtiyoni Endang
Published: July 2020

Research aims to examine obstacles found both internally and externally. Method of research using survey method. Research population is an alumnus of study and counseling Program of PGRI Palembang University. Samples were chosen using the Purposif method, which focused on alumni who have not worked after graduating from college. The data collection techniques used are the scale of confusion in choosing a career. The results showed that there were students ' barriers in planning careers with both internal and external factors, but the barriers were dominated by internal factors.