bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Ointment Containing Epithelial Growth Factor Compared with Antibacterial Ointment in Avulsive Laceration
Authors: Choi Youngwoong
Published: February 2020

Background: Avulsive lacerations are more likely to cause complications such as necrosis and dehiscence than vertical lacerations. In laceration wounds, topical antimicrobials can be effective because of their antibacterial properties that help eliminate infection or biofilms from the wound bed. However, indiscriminate or habitual use of antibiotics may cause bacterial tolerance. The purpose of this study was to evaluate the effectiveness of an ointment containing epidermal growth factor (EGF), effective in healing wounds involving epithelial and skin cells, compared with an antibiotic ointment for avulsive lacerations.Methods: We recruited patients who visited the emergency department with avulsive lacerations on their faces. The selected patients were randomly prescribed for dressing either an ofloxacin ointment or EGF ointment after repair. Epidemiologic information of patients, wound assessment (size, depth, and location) and wound healing result assessments (necrosis/dehiscence) were evaluated.Results: Of the 119 participants, 42 were women and 77 were men. The average length of the lacerations was 2.15 cm and most lacerations were in the muscle layer. There was no difference in the incidence of dehiscence and necrosis after use of either ointment, but the ratio of the necrotic area was significantly lower in EGF ointment group (antibiotics ointment, 2.33% and EGF ointment, 0%; P=0.03).Conclusion: We conclude that the ointment containing EGF can be used to replace the antimicrobial-containing ointment often used to prevent infection, which is in turn followed by skin or soft tissue necrosis.
Some aspects of online education training and retraining of physical education and sports
Authors: Filonenko N. V. , Ushakova N. A.
Published: February 2020

This article actualizes the problem of training and retraining of personnel in the physical education and sports industry. Based on the results of sociological surveys of students, the most acceptable time for conducting online classes is provided, as well as criteria for evaluating the quality of online lectures (webinars) formed by the authors to concentrate the attention of students during the classes.
Astilleros y Fábricas Navales del Estado. Demanda estatal, diversificación y orientación de la producción a la industria no militar en un proyecto empresarial de la Armada (1953 y 1976)
Authors: Barragán Ivonne
Published: February 2020

Este escrito busca aportar al conocimiento de la administración de empresas públicas realizada por la Armada Argentina a partir de la identificación de políticas empresariales desarrolladas en la empresa Astilleros y Fábricas Navales del Estado, que buscaron asegurar su viabilidad económica. Analiza una serie de estrategias productivas y de gestión técnica, económica y administrativa en el Astillero Río Santiago (1953-1976) a partir de documentación empresarial, libros contables y el registro de las negociaciones paritarias. La orientación singular de estas estrategias es construida a la luz de un conjunto de cuestiones como la relación con la Marina de Guerra; la diversificación y la orientación de la producción; la inserción en la estructura estatal y la calificación de la fuerza de trabajo.
La vida cotidiana en el centro clandestino “Olimpo”. Interacciones entre detenidos-desaparecidos
Authors: Cataldo Díaz Florencia
Published: February 2020

El trabajo aborda desde una nueva mirada el funcionamiento del centro clandestino de detención “Olimpo” entre agosto de 1978 y enero de 1979, durante la última dictadura argentina (1976-1983). Con tal fin analiza su dinámica cotidiana, a partir del análisis cualitativo de fuentes orales y escritas, enfocándose en las interacciones entre detenidos-desaparecidos y los elementos que las moldearon. Las principales conclusiones indican que aunque la desconfianza entre detenidos-desaparecidos subyació, primó el compañerismo; y que los lazos de socialización fueron el mecanismo de resistencia colectiva por excelencia, pues permitieron subsistir y restituir parte de la subjetividad arrebatada por el dispositivo represivo.
스펙경쟁 사회에서 자기계발 동기와 자기계발 강박이 취업준비생의 심리상태에 미치는 영향
Authors: Heo ChangGoo
Published: February 2020

본 연구는 대학생들의 스펙 쌓기와 관련된 심리상태 및 취업 준비행동의 특성을 살펴봄으로써 스펙 쌓기 과열현상을 심리학적 측면에서 이해하기 위해 수행되었다. 연구 1은 스펙추구라는 사회적 현상을 심리적 현상으로 개념화하기 위해 개인의 '자기계발'로 정의하고 이를 측정할 수 있는 자기계발 동기(증진적, 예방적) 척도와 강박적 자기계발 척도를 개발하였다. 개발된 세 가지 자기계발(증진적, 예방적, 강박적) 척도는 양호한 구성타당성을 보여주었으며 조절초점척도(증진, 예방), 학습지향성척도(숙달목표, 수행목표), 걱정 및 강박척도와 논리적으로 타당한 상관관계를 보여주었다. 연구 2는 세 가지 자기계발이 대학생들의 진로 및 취업 관련 심리변인(취업불안, 진로성숙도, 진로의사결정, 진로준비행동, 내면적 편견, 삶의 만족)에 미치는 영향을 확인하기 위해 수행되었다. 그 결과 증진적 자기계발의 긍정적인 영향에 대한 가설과 강박적 자기계발의 부정적인 영향에 대한 가설이 모두 지지되었다. 한편, 부정적인 영향을 미칠 것으로 가정했던 예방적 자기계발의 부정적인 영향은 관찰되지 않았다. 본 연구에서 개발한 도구와 연구결과는 진로지도 장면에서 과도한 자기계발로 불편을 호소하는 학생들의 진단과 상담 및 바람직한 자기계발 교육에 활용될 수 있을 것으로 기대한다.
Algal Oil as Source of Polyunsaturated Fatty Acids in Laying Hens Nutrition: Effect on Egg Performance, Egg Quality Indices and Fatty Acid Composition of Egg Yolk Lipids
Authors: Świątkiewicz Sylwester , Arczewska-Włosek Anna , Szczurek Witold , Calik Jolanta , Bederska-Łojewska Dorota , Orczewska-Dudek Sylwia , Muszyński Siemowit , Tomaszewska Ewa , Józefiak Damian
Published: February 2020

The aim of this study was to evaluate the effect of algal oil with very high level of docosahexaenoic acid (DHA, C22:6n-3) used as fat source in the diet for laying hens, on egg yolk lipids fatty acid composition, as well as egg production and egg quality indices, in comparison with other dietary fat sources. The experiment was carried out on 168 ISA Brown hens (25 to 60 wks of age), allocated to 7 groups of 12 replicates (cages), with two birds in each cage. The experimental diets were supplemented with 2% of different fat sources, i.e. soybean oil (SO), coconut oil (CO), rapeseed oil (RO), linseed oil (LO), camelina oil (CAO), fish oil (FO), or algal oil (AO). Laying performance indices, i.e. egg production, mean egg weight, feed intake, feed conversion ratio, or egg and eggshell quality parameters were not affected by used fat sources (P>0.05). Dietary fat sources significantly influenced on egg yolk lipids fatty acids composition. Thus, AO addition caused some changes in the yolk lipid profile that were favorable from the dietary perspective, i.e., increased concentration of eicosapentaenoic acid (EPA) and DHA (P<0.05). However, boiled eggs from hens fed a diet with AO were characterized by an inferior flavour and taste to those from other groups. In conclusion, the results of this experiment, have shown that the use of AO in the laying hens nutrition is an efficient way to increase the deposition of n-3 long chain polyunsaturated fatty acids (n-3 LCPUFAs) in eggs, without negative effect on egg performance, however further researches, aiming to establish optimal AO dietary level that does not adversely affect the organoleptic properties of eggs, are needed.
A new result on the quasi power increasing sequences
Authors: Özarslan Hikmet Seyhan
Published: February 2020

This paper presents a theorem dealing with absolute matrix summability of infinite series. This theorem has been proved taking quasi β-power increasing sequence instead of almost increasing sequence.
Spatial development of hydrological droughts in lake catchments
Authors: Kozek Malwina , Tomaszewski Edmund
Published: February 2020

In river-lake systems, reservoirs significantly affect the formation of water resources in the catchment by reducing the maximum flows and floods as well as increasing the low flows. In lake catchments, the pace of hydrological drought progression is usually slow. However, this phenomenon can be very extreme and destructive for water balance structure as a result of the very slow renewal rate of catchment resources. An estimation of hydrological drought development was conducted in the Biebrza river catchment (6,900 km2) on the basis of a daily discharge series for 18 water-gauge stations in the period 1982–2014. The number and location of the gauges allowed reliable results of the spatial pattern of drought to be obtained. The main objective of the research was the construction and assessment of the applicability of indicators which are estimators of drought spatial progression. Comparative analysis of four proposed indices led to two of them being recommended. These characteristics estimate the direction of drought development according to the stream network hierarchy, location of sub-catchments and the direction of river basin area increase. As a result, determinants of the spatial development of hydrological drought as well as its importance in the hydrographical structure were identified. Furthermore, the intensity of drought was evaluated and all investigated indices were applied to a time series analysis.
Analysis of quality of life in women treated for incontinence dependent on sociodemographic factors
Authors: Kanadys Katarzyna , Szczekala Katarzyna , Stadnicka Grażyna , Woźnica Ewelina , Wiktor Henryk
Published: February 2020

Introduction. Urinary incontinence (UI) constitutes involuntary leakage of urine and concerns an increasing number of women. It usually occurs in perimenopausal period; however, it may occur any time. Symptoms typical of incontinence cause massive discomfort that can affect the quality of life (QoL).

Aim. The assessment of the QoL in women suffering from UI dependent on sociodemographic variables.

Material and methods. The research encompassed 102 patients of the gynaecological wards of the Independent Clinical Hospital No 1 in Lublin and the Independent Public Clinical Hospital No 4 in Lublin. The inclusion criterion was as follows female patients diagnosed with urinary incontinence and treated in hospital. The study was voluntary and anonymous. The research project was approved by the Bioethics Committee of the Medical University of Lublin (No KE-0254/25/2016). The method of diagnostic survey was applied by means of the authors’ own questionnaire and the King’s Health Questionnaire (KHQ). The statistical analysis of the data results was carried out and p<0.05 was assumed as statistically significant.

Results. Age conditioned the QoL in the females researched regarding the influence of the urinary tract symptoms on their general health, partner relations and sleep. The females over 65 years of age showed worse QoL in comparison with the younger ones. Education did not affect the impact of urinary symptoms on the domains of the QoL using the KHQ. The marital status was a variable that influenced the respondents’ QoL. The married women had better QoL than the widowed or divorced ones. The financial situation conditioned the impact of the urinary symptoms on their general health, physical condition and sleep. The females with the average financial situation had worse QoL than those with good financial situation.

Conclusions. The QoL of women with UI depended on their age, marital status and financial situation. The females over 65 years of age who were widowed or divorced with the average financial situation were characterised by worse QoL than the younger and married women with good financial situation.
Biomarkers in Progressive Chronic Kidney Disease. Still a Long Way to Go
Authors: Ntrinias Theodoros , Papasotiriou Marios , Balta Lamprini , Kalavrizioti Dimitra , Vamvakas Sotirios , Papachristou Evangelos , Goumenos Dimitrios S.
Published: February 2020

The traditional chronic kidney disease (CKD) biomarkers (eGFR based on serum creatinine, sex and age and albuminuria) cannot predict a patient’s individual risk for developing progressive CKD. For this reason, it is necessary to identify novel CKD biomarkers that will be able to predict which patients are prone to develop progressive disease and discriminate between disease processes in different parts of the nephron (glomeruli or tubules).

A good biomarker should change before or simultaneously with lesion development and its changes should correlate strongly with lesion development. Also, there should be a close relationship between severity of injury and amount of detectable biomarker and its levels should decrease with diminishing injury.

Among the large number of molecules under investigation, we have reviewed the most promising ones: NGAL and KIM-1, MCP-1, MMP-9, clusterin, MMP-9, TIMP-1, Procollagen I alpha 1 and suPAR. All these, have been studied as biomarkers for prediction of CKD progression in cohorts of patients with chronic kidney disease of different stages and various aetiologies (proteinuric and non-proteinuric, glomerulonephritides, diabetic, hypertensive and polycystic kidney disease). There is evidence that these molecules could be useful as biomarkers for progressive chronic kidney disease, however, the available data are not enough to draw final conclusions. Further studies with large cohorts and long follow-up are required to identify appropriate biomarkers, that will be able to accurately and reliably define the risk for progressive chronic kidney disease.
Side Effects of Intravenous Patient-Controlled Analgesia with Remifentanil Compared with Intermittent Epidural Bolus for Labour Analgesia – A Randomized Controlled Trial
Authors: Karadjova Dafina , Shosholcheva Mirjana , Ivanov Еmilija , Sivevski Аtanas , Kjaev Ivo , Kartalov Adrijan , Kuzmanovska Biljana , Spasova Rosa , Kocovski Goran , Aleksiovska-Papestiev Irena
Published: February 2020

Introduction: Epidural analgesia is considered a gold standard in obstetric anaesthesia and analgesia. However, in situation when it is contraindicated, unwanted by the patient or simply unavailable, remifentanil can be an excellent alternative. The goal of our study is to analyse the side effects of intravenous patient-controlled analgesia (IV PCA) with remifentanil compared with epidural analgesia during delivery.

Material and methods: This study included 155 pregnant women in term for birth, divided into 2 groups: a remifentanil group (RG), and an epidural group (EG). Patients in the RG received intravenous PCA with remifentanil, while patients in the ЕG received epidural analgesia with programmed intermittent bolus dosing. Our primary outcome was maternal safety; the secondary outcome was neonatal safety.

Results: The results present a significantly lower SaO2 value of the parturients in the RG (96.95 ± 1.4 vs 98.22 ± 0.6), and a significantly higher respiratory rate per minute in the EG at all time points after the onset of analgesia (20.85 ± 1.4 vs 18.67 ± 0.9). There was more frequent sedation, nausea and vomiting in the RG, while in the EG there was a more elevated temperature, itching and irregularities in the CTG record. Regarding the newborn, there was no significant difference between the two groups in the Apgar scores, pH, pCO2, pO2, and bicarbonate, while there was a significantly lower value of the base excess in the RG group.

Conclusion: PCA with remifentanil is safe for the mother, foetus and the newborn, with minimal side effects. Continuous respiratory monitoring, oxygen supply and following of all consensus recommendations are mandatory.
Blue Growth Potential in South Baltic Sea Region
Authors: Philipp Robert , Prause Gunnar , Meyer Christopher
Published: February 2020

The Baltic Sea Region (BSR) stands for a flagship maritime region in Europe with dominating SME sector. Nevertheless, compared with other European regions, the cooperation and promotion activities of companies that belong to the Blue Economy in South Baltic Sea Region (SBSR) are not sufficient. As a response to this, the EU-project INTERMARE South Baltic aims to support the maritime economy in the SBSR by the creation of a network of companies and stakeholders.

In line with the project, this study aims to analyse the future potential of the maritime economy and to identify trends that impact the sustainable development of the blue sector in SBSR. Based on primary data from a SBSR wide survey, descriptive statistical analysis is applied and Compound Annual Growth Rate is used as an indicator. The findings reveal need for actions regarding the sub-sectors Transport, Offshore oil & gas, Aquaculture, Fishery, Mineral resources and Biotechnology.
IMMIGRANTS’ EDUCATIONAL RIGHTS
Authors: Garrido Rodriguez Pedro
Published: February 2020

Within the set of human rights agreed and universally recognized, the right to education occupies a priority place. Everyone assumes that education must be guaranteed, compulsory and free, at least for minors. However, there is still a very significant group of people who do not enjoy their educational rights. Migrants, excluded persons and lack of resources are those that most de facto lack this universal basic right. The United Nations has made some proposals to resolve this problem, such as Objective No. 4 of the Sustainable Development Goals: Ensure equitable and quality education. This article thoroughly analyzes the main initiatives built in recent years in the international context.
STATE, EUROPEAN INTEGRATION, AND GLOBALIZATION. NEW CHALLENGES FOR CONSTITUTIONALISM
Authors: Mangiameli Stelio
Published: February 2020

The essay takes into consideration the current relations between the State, European integration and globalization, with reference to the principles of constitutionalism.The principles of constitutionalism, such as the division of powers, the guarantee of the fundamental rights, federalism and representative democracy, are examined in the light of modern and contemporary statehood, which shape the constitutional state. The processes of integration of financial markets and modern technologies, as well as economic crises, have impacted on the constitutional state and revealed the insufficiency and inadequacy of state institutions in terms of size and capacity. Hence the idea of the constitutionalization of Europe by the Member States as a remedy to reaffirm the safeguarding of fundamental rights and the guarantee of a democracy of proximity. Furthermore, international processes have accelerated the transition to a global market, which has undermined the sovereignty of states and their political weight. However, in such a context, States can only recover their role if the principles of constitutionalism are applied in the international order, so that the sovereignty of States opens up towards an international order which is characterized by inter-state cooperation and promotion of universal principles.
Yeni ve Eski Buğday Çeşitlerinin Yüksek Yetişme Sıcaklığında Gelişimlerinin Karşılaştırılması
Authors: Atar Bekir
Published: February 2020

Buğdayda yaklaşık 10 bin yıldır doğal veya suni olarak yeni çeşitler ortaya çıkmaktadır. İnsanoğlu tarafından geliştirilen çeşitler de en önemli kriterler olarak verim, gübre ve makine kullanımı, değişen lezzet tercihleri ile iklim değişikliklerine uyum sayılabilir. Yapılan bu çalışmada; yeni geliştirilen çeşitlerden olan, vernalizasyon ve fotoperiyot hassasiyeti düşük USU-Apogee çeşidi ile daha önce geliştirilen çeşitlerden olan Einkorn ve Emmer ile yine ülkemizde geliştirilen alternatif gelişme tabiatlı Tosunbey çeşidi agronomik özellikler bakımından karşılaştırılmıştır. Araştırma oda sıcaklığında ve yazlık ekim olarak tarla koşullarında yürütülmüştür. Oda sıcaklığında yetiştirmede Apogee çeşidi 87 günde, Emmer çeşidi 140 günde, Tosunbey çeşidi 116 günde hasat olgunluğuna gelmiştir. Einkorn çeşidinin gelişimi vernalizasyon ihtiyacını karşılayamadığından dolayı sapa kalkma döneminde durmuştur. Tarla denemelerinde ise tüm çeşitler vernalizasyon ihtiyacını karşılayarak gelişimlerini tamamlamışlardır. Apogee çeşidi 93 günde, Einkorn çeşidi 118 günde, Emmer çeşidi 108 günde, Tosunbey çeşidi 115 günde hasat olgunluğuna gelmiştir. Apogee çeşidi arazi koşullarında daha geç olgunlaşırken, diğer çeşitler daha erken olgunlaşmışlardır. Oda sıcaklığında yetiştirmede bin tane ağırlıkları Apogee çeşidinde 24,2 g, Emmer çeşidinde 17,4 g, Tosunbey çeşidinde 26,5 g bulunurken, tarla denemelerinde Apogee çeşidinde 11,3 g, Einkorn çeşidinde 20,3 g, Emmer çeşidinde 24,7 g, Tosunbey çeşidinde 26,0 g olarak belirlenmiştir. Tarla denemelerinde Apogee çeşidinde bin tane ağırlığı belirgin olarak azalmıştır.
Bazı Çiğ Olarak Tüketilen Mor Sebzelerin Etanol Ekstraktlarının Gıda Kaynaklı Küfler Üzerindeki Antifungal Etkileri
Authors: Akarca Gökhan , Tomar Oktay , Başpınar Elif , Yıldırım Gamze
Published: February 2020

Sebzeler; vitamin, besinsel lif, fenolik bileşen ve mineral madde bakımından insan beslenmesinde önemli bir role sahiptir. Mor-kırmızı renkli sebzelerin birçok türü olup bunlardan en bilinen türlerinden bazıları kırmızı pancar (Beta vulgaris), kara havuç (Daucus carota ssp. sativus var. atrorubens Alef), kara turp (Raphanus sativus L. var. niger), Mor lahana (Brassica oleracea L. var. capitata f. rubra) gibi sebzelerdir. Mor veya kırmızı renkli sebzeler diğer sebzelere kıyasla daha yüksek antioksidan potansiyeline sahip olup, antioksidan etkilerinin yanı sıra antimikrobiyal, antifungal, antiinflamatuar, karaciğer koruyucu gibi birçok faydalı özellikleri bulunur. Kara havuç, kırmızı pancar, kara turp ve mor lahana sebzelerinin her biri sırasıyla p-kumarik asit, betaksantin, elajik asit ve indol-3-karbinol içerir. Çalışmamızda; kırmızı pancar, kara havuç, kara turp iç ve kabuk kısımları ile mor lahanadan elde edilen etanol ekstraktlarının 7 farklı Penicillium, 6 farklı Aspergillus türleri ile Mucor racemosus, Botrytis cinerea, Geotrichum candidum, Cladosporium claudosporioides, Rhizopus nigricans türlerine karşı antifungal etkisi disk difüzyon yöntemi ile belirlenmiştir. Sonuç olarak, 7 farklı örneğin 18 farklı küf türü üzerinde değişik oranlarda antifungal etkisinin olduğu tespit edilmiştir. En yüksek antifungal etki 23,05±0,05 mm zon çapı ile A. fumigatus‘a karşı kara turp iç etanol ekstraktında gözlenmiştir. Bu değeri 21,44±0,12 mm zon çapı ile M. racemosus‘a karşı kırmızı pancar iç etanol ekstraktı takip etmiştir. Mor lahana ekstraktının P. citrinum, P. solitum ve B. cinerea türleri hariç diğer küf türleri üzerinde en az antifungal etkiye sahip olduğu belirlenmiştir.
Radyal Tabanlı Yapay Sinir Ağlarının Kurutma Kinetiğinin Modellenmesinde Kullanımı
Authors: Yıldız Adil Koray , Taşova Muhammed , Polatcı Hakan
Published: February 2020

Ürünlerin dayanımını arttırma, taşıma ve depolama gibi birçok işlemde avantaj sağladığı için tarımsal ürünlerde kurutma yöntemi tercih edilmektedir. Ürün kalitesini düşürmeden en iyi şekilde kurutma işleminin yapılabilmesi için ürünlerin kuruma davranışını tahmin etmek gereklidir. Bu nedenle ürünlerin kuruma kinetiğinin tahmini için birçok sayısal kuruma modeli geliştirilmiştir. Son zamanlarda bu modellerin geliştirilmesi için yapay sinir ağları yaygın olarak kullanılmaktadır. Yapay sinir ağları, doğal sinir hücrelerine benzer şekilde çalışan matematiksel modellerdir. Radyal tabanlı yapay sinir ağları ise diğer ağlardan farklı olarak gizli katmana geçişte radyal tabanlı aktivasyon fonksiyonları bulunduran ağlardır. Bu çalışmada, kurutma kinetiğinin radyal tabanlı ağlar ile modellenebilmesi araştırılmıştır. Deney çalışması için kırmızı acı bibere (Capsicum annuum L.) kaynamış suya bandırma ve mikrodalga ön işlemleri uygulanarak etüvde 65Â°C sıcaklıkta kurutulmuştur. Kuruma süresince alınabilir nem oranı değerleri hesaplanmış ve kuruma süresi değerleri giriş, uzaklaştırılabilir nem oranı değerleri ise çıkış olacak şekilde Radyal Tabanlı Yapay Sinir Ağı modelleri eğitilmiştir. Tüm veri ve aynı sürelerde ölçülen değerlerin ortalamasıyla oluşturulan ortalama veri ayrı ayrı denenmiştir. Tüm veri ile olan eğitimlerde R değeri 0,9566; ortalama ile olanlarda 0,9998 olarak hesaplanmıştır.
Crítica pedagógica y antropopedagogía: hacia una nueva problematización del Estado
Authors: Cárdenas López Gustavo Adolfo
Published: February 2020

Si asumimos el poder como técnicas de control sobre la vida, el panorama en torno a posibilidades de despliegue de la vida y su potencial parece ser cada vez más incierto, sobre todo porque la capacidad de codificación y de registro por parte del Estado se ha tecnificado a tal punto, que ya ni siquiera es posible establecer un límite que separe al Estado de la población civil. Ya no es posible entender el estado de las formas como lo habíamos tomado en occidente en épocas anteriores, pues está en todos nosotros y determina por completo todas nuestras relaciones. No es un “afuera” pero tampoco un “adentro”, es un “entre”. Ahora bien, si hay algo que se resiste al poder y sus técnicas de control, es la vida misma, pero tal resistencia va disminuyendo (sin desaparecer) conforme las técnicas de control se van instalando en cada humano; por esta razón, la atención filosófica tiene que, ineludiblemente, centrarse en la niñez y en cómo se dan los procesos de formación de los menores, es decir, de qué manera es expulsado el animal del cuerpo para instalar en él al ciudadano, lo cual lleva inevitablemente a un cuestionamiento de la relación entre filosofía y educación, ya que quizá no nos hayamos tomado suficientemente en serio la tercera transformación del espíritu. La pedagogía como saber institucional, que históricamente parece haber bebido más de la psicología que de la filosofía, es por completo incapaz de hacer un análisis por fuera de los límites que le impone la institucionalidad y por eso, se hace necesaria la emergencia de una crítica pedagógica que sea crítica de la pedagogía en cuanto a saber institucional, y que sea capaz de analizar la contracara de la escuela institución, esta es, la configuración de máquinas de guerra que se resisten a tal escuela y crean otra, la escuela máquina de guerra, la cual no es otra cosa que resistencia y ruptura ante la institucionalidad, y que se convierte a su vez, en un nuevo cuestionamiento al Estado. Para ello, ha de usar la antropopedagogía, que supera la pregunta clásica de la antropología acerca de ¿qué es el hombre? y se plantea un cuestionamiento de otro tipo, a saber ¿cómo un animal deviene humano?
Utilización de las zonas de entrada seguras para el abordaje de lesiones intrínsecas de tronco cerebral en adultos
Authors: Rabadán Alejandra T.
Published: February 2020

Introducción:

Las “zonas de entrada seguras” (ZES) al tronco cerebral describen accesos destinados a preservar estructuras críticas. La mayoría de las publicaciones son descripciones anatómicas; existiendo pocas sobre su aplicación. En este escenario, nuestro trabajo puede sumar información para el manejo quirúrgico en casos seleccionados.

Material y Métodos:

De una serie de 13 pacientes, se presentan 9 que no eran candidatos para biopsia estereotáctica y recibieron microcirugía. Las localizaciones fueron: mesencéfalo (3), tectum (1), protuberancia (2) y bulbo (3). Cinco pacientes tuvieron KPS ≥70; y 4, KPS <70. Diferentes ZES fueron utilizadas según la topografía lesional. El grado de resección se basó en la biopsia intraoperatoria y el monitoreo neurofisiológico.

Resultados:

Los hallazgos patológicos fueron: astrocitoma pilocítico (1), glioma de bajo grado (1), hemangioblastoma (1), subependimoma (1), disgerminoma (1), y lesiones pseudotumorales (3 cavernomas y 1 pseudotumor inflamatorio). El grado de resección fue completo (4), subtotal (3), y biopsia fue considerada suficiente en (2). Un paciente falleció en el postoperatorio.

Discusión:

Las lesiones del tronco cerebral son infrecuentes en adultos. Las controversias surgen cuando se balancean los beneficios de obtener diagnóstico histopatológico y los riesgos potenciales de procedimientos invasivos. La amplia variedad de hallazgos en esta localización exige una precisa definición histopatológica, que no solamente determinará la terapéutica adecuada, sino que advierte sobre las consecuencias potencialmente catastróficas de los tratamientos empíricos. Las ZES ofrecen un acceso posible y seguro, aunque es más realista considerarlas como áreas para abordar lesiones intrínsecas con baja morbilidad más que como zonas completamente seguras.
An Unprecedented Octahedral Trifluoromagnesate MgF3(Wat)– Transition State Analog Reveals The Molecular Mechanism of ATP Hydrolysis by Zika Virus Helicase
Authors: Ge Mengyu , Molt Jr Robert W. , Jenkins Huw T. , Blackburn G. Michael , Jin Yi , Antson Alfred A.
Published: February 2020

Metal fluoride complexes mimic the transferring phosphoryl group in many enzyme-catalyzed reactions. We here employ the trifluoromagnesate transition state analog (TSA) to study a Zika virus NS3h helicase, which uses energy from ATP hydrolysis to reorganize ssRNA leading to completion of virus replication. The crystal structure of this TSA complex displays two conformations for a catalytically important loop, demonstrating how ATP hydrolysis can be coupled with RNA translocation. Unexpectedly, the trifluoromagnesate core of this transition state complex is octahedral. It is identified as having an unprecedented MgF3(Wat)– ligand, confirmed by 19F NMR analysis. This structure was further probed by quantum mechanical calculations of the catalytic core (200 atoms), confirming the structural data interpretation and the concerted mechanism of ATP hydrolysis by this class of helicase. The formation of this MgF3(Wat)– ligand in helicase but not in other multiple MFx structures for ATPases and GTPases strongly implies they cannot possess such an additional water in their active sites.
Self-Healing Injectable Polymer Hydrogel via Dynamic Thiol-Alkynone Double Addition Crosslinks
Authors: fan bowen , Zhang Kai , Liu Qian , Eelkema Rienk
Published: February 2020

Introduction of dynamic thiol-alkynone double addition crosslinks in a polymer network enable the formation of a self-healing injectable polymer hydrogel. A 4-arm polyethylene glycol (PEG) tetra-thiol star polymer is crosslinked by a small molecule alkynone via the thiol-alkynone double adduct, to generate a hydrogel network under ambient aqueous conditions (buffer pH=7.4 or 8.2, room temperature). The mechanical properties of these hydrogels can be easily tuned by varying the concentration of polymer precursors. Through the dynamic thiol-alkynone double addition crosslink, these hydrogels are self-healing and shear thinning, as demonstrated by rheological measurements, macroscopic self-healing and injection tests. These hydrogels can be injected through a 20G syringe needle and recover after extrusion. In addition, good cytocompatibility of these hydrogels is confirmed by cytotoxicity test. This work shows the application of a new type of dynamic covalent chemistry in the straightforward preparation of self-healing injectable hydrogels, which may find future biomedical applications such as tissue engineering and drug delivery.
KOSI EJE KOSI ORISA: RACISMO RELIGIOSO E CRIMINALIZAÇÃO DAS RELIGIÕES DE MATRIZ AFRICANA NO PROJETO DE LEI Nº. 230∕1999
Authors: RAMOS Luciana De Souza
Published: February 2020

Como uma religião que cultua a força viva da natureza, os orixás, tudo que é feito dentro dos terreiros vem e voltam para ela. O presente trabalho visa analisar a dimensão do racismo religioso e o processo de criminalização contra as religiões de matriz africana, pela imolação de animais, a partir do Projeto de Lei (PL) 230∕1999 do Estado do Rio Grande do Sul. A metodologia é bibliográfica, por meio da análise constitucional do PL, bem como da decisão Supremo Tribunal Federal (STF).
A POLICIZAÇÃO DA JUSTIÇA: UMA ANÁLISE SOBRE A HIPÓTESE DE FOUCAULT NO SISTEMA DE JUSTIÇA CRIMINAL BRASILEIRO A PARTIR DO DIREITO AO CONTRADITÓRIO
Authors: Santoro Antonio Eduardo Ramires , Tavares Natália Lucero Frias
Published: February 2020

A partir da hipótese apresentada por Michel Foucault de que a Justiça está a serviço da polícia, este trabalho pretende responder à pergunta se essa assertiva se verifica no Brasil, configurando-se seu problema central. Para realizou-se uma pesquisa sobre o sistema processual penal de garantias no Brasil, bem como as formas peculiares de produção de informações por meio de provas conforme os desenhos processuais penais que se apresentam na prática judicial brasileira. Confirmou-se a hipótese de Foucault em razão do uso demasiado de informações produzidas na fase policial ou pela oitava de policiais nas decisões judiciais.
A APLICAÇÃO DOS NUDGES NA PRESERVAÇÃO DO LIVRE ARBÍTRIO EM AUDIÊNCIAS JUDICIAIS DE CONCILIAÇÃO E MEDIAÇÃO
Authors: Weyne Denise Lage Bezerra
Published: February 2020

O presente artigo analisa os institutos da conciliação e mediação judicial e a correlata legislação que determina a imposição de multa para o não comparecimento injustificado das partes à audiência de conciliação e mediação. Sugere-se que a saída para a valorização dos meios consensuais que mais se coaduna com suas características é o paternalismo libertário e não o intervencionismo estatal. Conclui que a utilização de simples estratégias pode trazer a tão esperada mudança de mentalidade social da cultura demandista, pois através dos nudges consegue-se chegar ao ápice das características dos meios consensuais.
Analisis Kualitas Mie Basah dengan Penambahan Daun Ubi Jalar Ungu (Ipomoea batatas)
Authors: Ahmad Hasmawati , Mustarin Amirah , Fadilah Ratnawaty
Published: February 2020

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan ekstrak daun ubi jalar ungu terhadap kualitas mie basah. Penelitian ini menggunakan metode penelitian eksperimen Rancangan Acak Lengkap (RAL) dengan konsentrasi perbandingan tepung ubi jalar ungu dan tepung terigu (30% : 70%), dan penambahan ekstrak daun ubi jalar ungu 0%, 2,5%, serta 5%. Tahap pertama penelitian yaitu irisan ubi jalar ungu dikeringkan menggunakan cabinet dryer selama 5 jam dengan suhu 60oC, kemudian dihaluskan dan diayak sehingga menghasilkan tepung. Tahap kedua yaitu daun ubi jalar ungu diekstrasi dengan metode maserasi yang dipekatkan menggunakan evaporator vakum. Tahap ketiga yaitu pembuatan mie basah berbahan dasar tepung terigu dan tepung ubi jalar ungu dengan penambahan ekstrak daun ubi jalar ungu. Data hasil pengamatan dianalisis menggunakan analisis sidik ragam (ANOVA) kemudian dilanjutkan dengan uji Duncan. Parameter yang diuji adalah kadar air, kadar abu, kadar protein, angka lempeng total (ALT), antioksidan dan uji hedonik (warna, rasa, aroma, serta tekstur). Hasil penelitian yang diperoleh bahwa penambahan ekstrak daun ubi jalar ungu memberikan pengaruh sangat nyata terhadap kadar air, kadar abu, kadar protein, angka lempeng total (ALT), antioksidan, warna, rasa, aroma, dan tekstur dari mie basah yang dihasilkan. Perlakuan terbaik pada penelitian ini yaitu penambahan ekstrak daun ubi jalar ungu 5%.
Rancang Bangun Alat Pembelah Buah Kakao (Theobroma cacao) Semi Mekanis
Authors: Hermawati Hermawati , Jamaluddin Jamaluddin , Lahming Lahming
Published: February 2020

Penelitian ini adalah penelitian rekayasa atau rancang bangun yang membahas tentang kerja dan unjuk kerja dengan alat pembelah buah kakao semi mekanis. Proses penelitian ini menambahkan pembuatan setiap komponen, memeriksa alat pembelah buah kakao serta melakukan pengujian. Penelitian ini menghasilkan alat pembelah buah kakao yang bekerja dengan menggunakan sistem tekan ( pers ), di mana pembua dapat mengaktifkan buah kakao hingga terbelah atau terpecah. Proses pengujian dilakukan pada kali ulangan, dengan sekali tekan dapat memecah tiga buah kakao.Hasil dari pengujian alat ini menghasilkan rata-rata kapasitas efektif alat 1126 buah / jam, kerusakan hasil rata-rata biji rusak 2,4%, biji tidak tersaring 57,8% menghasilkan persenikatan penuh 97,6% dan rata-rata persentase biji tersaring hanya 42,2%, serta rendemen 100%. Berdasarkan hasil penelitian yang diperoleh dari kerja mekanik pembelah semi mekanis ini meningkat dan dapat mengurangi kerja dan kerusakan biji yang dihasilkan menggunakan dengan pembelahan manual yang menggunakan pisau atau golok yang diperuntukkan untuk buah kakao yang dibelanjakan untuk diganti hama penggerek buah.
A new three-dimensional Co(II)-mixed-ligand MOF: A protective effect against acute cerebral infarction by reducing the hs-crp content and inflammatory response
Authors: Xu J. , Li P. , He B. , Gu H. , Zhuang J. , Peng H.
Published: February 2020

A novel Co(II)-based metal-organic framework (MOF) {[Co2(TCPP)(BPY)](DMF)3}n (1) with a pillared structure based on 2,3,5,6-tetrakis(4-carboxyphenyl)pyrazine (H4TCPP) and 4,4'-bipyridine (BPY) is designed and synthesized via the solvothermal reaction. Furthermore, a green-hand grinding technique is implemented to reduce the particle size of complex 1 to generate nanoscale 1 (denoted as nano-1 hereafter). After the construction of the acute cerebral infarction animal model, the infarct area of the brain is measured after 2 weeks of treatment with the compound. Then, ELISA is performed to detect the content of hs-CRP and IL-1b and TNF-a in the serum.
Pontocerebellar hypoplasia: clinical case and literature review
Authors: Anužis L. , Buivydas E. , Petrova D. , Šukys M. , Gleiznienė R.
Published: February 2020

Pontocerebellar hypoplasia (PCH) is a group of rare neurodegenerative disorders which start in the intrauterine period and are inherited by autosomal recessive way. Structural changes caused by the mutation include cerebellar hypoplasia or atrophy, microcephalus, and hypoplasia of ventral pons. Clinical signs and symptoms are present in neonatal period or infancy. Progressive microcephalus, sucking and swallowing disorders, jitteriness, generalized clonus, insufficient development of voluntary movements and cognitive functions, and dystonia can be observed. Magnetic resonance imaging (MRI) along with clinical signs and symptoms is very important in suspecting and diagnosing PCH. Most common MRI features include dragonfly configuration cerebellum in coronal sections, absent or severely reduced in size pontine prominence, various degrees of cerebral cortex atrophy, and delayed myelination. To confirm the diagnosis of PCH2A, genetic analysis is required detecting homozygous missense mutation in the TSEN54 gene. In this article we present a clinical case of a neonate whose diagnosis of PCH2A was suspected by clinical symptoms and MRI features and later confirmed by identifying homozygous missense mutation in the TSEN54 gene.
Variación intraespecífica de rasgos funcionales de Cedrela odorata L. en la Península de Nicoya, Costa Rica
Authors: Galindo Segura Luis Alan , Finegan Bryan , Delgado-Rodríguez Diego , Mesén Sequiera Francisco
Published: February 2020

El cambio climático modificará el régimen hidrológico global a causa de alteraciones en la magnitud de la precipitación y temperatura, y su interacción con las condiciones físicas y de vegetación de cada lugar; esto representa un gran riesgo para la conservación de las especies, ya que implica variaciones en las condiciones que les son cruciales para su desarrollo. En respuesta a los factores abióticos y bióticos del hábitat, las plantas muestran gran variabilidad intraespecífica de rasgos, esta habilidad les permite sobrevivir, crecer y reproducirse en diversos escenarios. Estudiar la variabilidad intraespecífica de caracteres morfológicos conlleva a entender el potencial de respuesta de las especies a factores de alteración, como el cambio climático. El objetivo del presente estudio fue evaluar la variabilidad intraespecífica del área foliar (mm2), el área foliar específica (mm-2 mg), contenido de materia seca foliar (mg-1 g), densidad de madera (g cm-3) y grosor de corteza (cm) de 90 individuos de Cedrela odorata en tres bosques naturales con distintos regímenes de precipitación anual. A partir de la hipótesis de que C. odorata podría modular la magnitud de expresión de los caracteres morfológicos antes mencionados, de acuerdo con las diferentes condiciones de precipitación. Los resultados demostraron que los valores de los atributos funcionales variaron significativamente entre las poblaciones estudiadas; además, se evidenció que el taxón expresó sus rasgos en un eje de especialización adquisitivo-conservativo en el uso de los recursos. La variabilidad intraespecífica de rasgos en C. odorata podría ser un mecanismo de resiliencia ante el cambio climático.
Corrosion Inhibition Efficiency Of Nicotine Based On Quantum Chemical Study
Authors: Wirayani Yayuk , Ulfa Maria , Yahmin Yahmin
Published: February 2020

The effect of substituents, electron donor groups (NH2, OH, CH2OH and CH3) and electron withdrawal groups (NO2, COOH, and Cl),  to the efficiency of corrosion inhibition of nicotine has been studied using theoretical studies. The effect of substituents toward the efficiency of corrosion inhibition of nicotine based on quantum parameters (EHOMO, ELUMO, Egap, I, Ï‡, dan Î”N). The efficiency of corrosion inhibition based on quantum parameters is NH2 > OH > CH2OH > CH3 > BN > Cl > COOH > NO2. The addition of electron donor group NH2 has the highest inhibitory efficiency of 99.79 %. In contrast, the presence of electron withdrawal group NO2 has the opposite effect.
Pengembangan modul berdasarkan pemecahan masalah polya pada mata kuliah analisis vektor
Authors: Yohanie Dian Devita , Samijo Samijo
Published: February 2020

Tujuan penelitian ini  ingin memgembangkan  modul berdasarkan pemecahan masalah Polya pada mata kuliah analisis vektor yang valid. Modul dikembangkan sesuai model 4D Thiaragajan. Modul dinilai oleh validator materi dan bahasa, validator media  dan  desain  pembelajaran,  praktisi  sesuai  dengan  angket.  Hasil  pengembangan modul analisis vektor berdasarkan penilaian validator materi dan bahasa 89,4%, validator media  dan  desain  pembelajaran  98%,  validator  praktisi  91,35%.  Angket  respon mahasiswa mendapat nilai 82,7%. Dapat disimpulkan modul berdasarkan pemecahan masalah Polya pada mata kuliah analisis vektor sangat valid dan layak digunakan untuk pembelajaran
TÜRKİYE’DE GÖÇ ÜZERİNE YAPILAN DOKTORA TEZLERİNE YÖNELİK BİR İÇERİK ANALİZİ
Authors: Alkar Elif , Atasoy Emin
Published: February 2020

Bu araştırma, 1988-2018 yılları arasında Türkiye’de göç alanında yapılan doktora tezlerinin içerik analizini ortaya koymak amacıyla gerçekleştirilmiştir. Araştırma sürecinde elde edilen veriler Ulusal Tez Merkezi’nde erişime açık olan toplam 212 doktora tezine dayanılarak oluşturulmuştur. Doktora tezleri; yayın yılı, üniversite, enstitü, anabilim dalı, konu alanı, göç türü, araştırma deseni, örneklem, örneklem büyüklüğü, veri toplama teknikleri ve araçları, özgün dil ve araştırmacının cinsiyeti göz önüne alınarak incelenmiştir.
Çalışmada, tarama yöntemi ile bir içerik analizi yapılmış elde edilen bulgular; yüzde, frekans, tablo ve grafikler halinde sunulmuştur. Analizler sonucunda göç alanında en fazla doktora tezinin 2008-2012 yılları arasında yazıldığı bulgusuna ulaşılmıştır. Doktora tezlerinin yapıldığı bilim dalları irdelendiğinde en fazla sosyoloji, tarih, uluslararası ilişkiler, siyasal bilimler ve ekonomi alanlarında çalışmaların yapıldığı tespit edilmiştir. Ayrıca yapılan incelemeler socunda veri toplama tekniği ve analizi olarak nitel araştırma desenleri kapsamında görüşmelerin ve doküman analizinin yoğunlukta olduğu bulgularına ulaşılmıştır.
DEVELOPING A PORTFOLIO OPTIMIZATION MODEL BASED ON LINEAR PROGRAMMING UNDER CERTAIN CONSTRAINTS: AN APPLICATION ON BORSA ISTANBUL 30 INDEX
Authors: Erdaş Mehmet Levent
Published: February 2020

The aims of this study are to lend assistance for the account owners who plan to make an investment in the financial markets to make the most accurate investments possible; accordingly, to develop a portfolio selection model and present it with its implementations. Instead of the L2 (standard deviation), risk function which is approached as a risk by Markowitz, the L1 (absolute deviation) risk function was used in the study and the optimal portfolios were trying to be attained. After the data acquired from the index of the Borsa Istanbul 30 index, the portfolio optimization model which is based on linear programming and was developed by Ching-Ter Chang (2005) was embraced in order to create an optimal portfolio. In this model, a new model was proposed by adding a limit on trading volume to reduce the systematic risk of the portfolio with the idea that it is one of the important indicators of the market and that it can create a decision-making risk perception. Thus, it was enabled for the portfolio to contain the equities from the industrial branch in desired numbers in accordance with the desire of the investors by adding the preference constraints on the Chang model. It can be said that this study will be useful for the investors and the finance executives who want to create a portfolio on specific risk and return level.
Comunicazione e graphic design della Biennale di Venezia (1895-1950)
Authors: Fontana Cristina
Published: February 2020

Between 1985 and 1950 Venice Biennale was very focused on advertising and posters. In those early years advertising was organized by Antonio Fradeletto, Romolo Bazzoni and Augusto Sezanne, the official graphic designer of the pre-war biennials, that created also the Biennale brand. Over the years, communication strategies of the Institution developed due to personalities such as Pica, Maraini and Pallucchini. Biennale posters were fundamental to give visibility to the institution in the world. An accurate graphic design and an allusion to Venice contributed to spread a truly significant image of the exhibition.
Dell'Archivio Storico delle Arti Contemporanee «la Biblioteca n’era il principio»
Authors: Marchesin Giorgia
Published: February 2020

The essay aims to reconstruct the history and to provide a library analysis about one of the most important libraries of contemporary art in Italy: the Library of the Venice Biennale. The library has been the founding fulcrum of what today is ASAC: Historical Archive of Contemporary Arts of the Venice Biennale. Its long history can be reconstructed by retracing the move of which it has been the protagonist, from the beginning in a small room on the ground floor of the Palazzo Ducale, to the current location inside the Central Pavilion of the Biennale Gardens. The heritage of books is in continuous development thanks to the Book Pavilion project and a network of exchanges between the most important artistic and cultural institutions. Today the Library heritage includes over 153,000 publications and over 3,000 periodicals. This invaluable collection, for the world of contemporary art, offers almost 23,000 volumes owned, in Italy, exclusively from the Library of the Venice Biennale.
‘Dans les pierres, il ne peut y avoir de fiction’ ?
Authors: Béhar Roland , Bernard Gwladys
Published: February 2020

Rodrigo Caro (1573-1647) has long been considered an unreliable witness of the epigraphic tradition, first and foremost by E. Hübner (CILII). This article reconsiders his role in the transmission of theConventus Hispalensis’falsae vel incertae, after a careful analysis of Caro’sAntigüedades de Sevilla(1634). Within this work, the Sevillian humanist overall appears to be scrupulous: it is only his duty to superior interests, such as those of the archbishopric of Seville, which forces him (as in his defense of the pseudo-Dexter) to reluctantly retain certainfalsaeincluded in theAntigüedades.
Le iscrizioni dell’album del Louvre di Jacopo Bellini
Authors: Fasolini Donato
Published: February 2020

Even if Jacopo Bellini may not quite be compared to his son-in-law Andrea Mantegna for his reputation as a ‘lover of antiquities’, his drawing book, now kept at the Louvre, contains two famous sheets of Roman inscriptions, which deserve special attention. This essay assesses the reliability of Bellini’s drawings in order to understand how much and what kind of information he can give us about some inscriptions, which are currently for the greater part lost.
Vicende di un falso senatoconsulto
Authors: Buongiorno Pierangelo
Published: February 2020

This paper aims to reconstruct the origins of the so-called Decretum Rubiconis (CIL XI 30*) and the ancient sources that inspired it (Cicero’s Philippics; Vergil; Seneca; the lex de imperio Vespasiani). The text was significantly manipulated by Ciriaco de’ Pizzicolli before the mid 15th century and was identified as false already by Antonio Agustín (Diálogos, 1587). Despite this prompt identification, the forged epigraphic document had a wide circulation in the manuscript tradition and (at least) two different engravings after the 16th century. A copy of the inscription is now kept in the Museum of Cesena.