bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Outcomes and Reoperation Rates After Hip Arthroscopy in Female Athletes With Low Versus Normal Body Mass Index: A Propensity-Matched Comparison With Minimum 2-Year Follow-up
Authors: Jimenez Andrew E. , Monahan Peter F. , Owens Jade S. , Maldonado David R. , Saks Benjamin R. , Ankem Hari K. , Sabetian Payam W. , Lall Ajay C. , Domb Benjamin G.
Published: November 2021

Background:

The effect of low body mass index (BMI) on outcomes in female athletes is unknown.

Purpose:

(1) To report minimum 2-year patient-reported outcomes and return to sports for high-level female athletes with low BMI undergoing hip arthroscopy for femoroacetabular impingement syndrome and (2) to compare results with those of a propensity-matched control group of high-level female athletes with a normal BMI.

Study Design:

Cohort study; Level of evidence, 3.

Methods:

Data were collected on all professional, collegiate, and high school female athletes who had a low BMI and underwent primary hip arthroscopy between September 2009 and March 2017 at our institute. Return-to-sports status and minimum 2-year patient-reported outcomes were collected for the modified Harris Hip Score (mHHS), Nonarthritic Hip Score, Hip Outcome Score–Sport Specific Subscale, and visual analog scale (VAS) for pain. The percentage of patients achieving the minimal clinically important difference (MCID), Patient Acceptable Symptom State (PASS), and maximum outcome improvement satisfaction threshold (MOIST) was also recorded. These patients were propensity matched to high-level female athletes with a normal BMI for comparison.

Results:

A total of 21 high-level female athletes (25 hips) with a mean ± SD follow-up of 58.9 ± 31.5 months were included. They demonstrated significant improvement from preoperatively to latest follow-up for the mHHS, Nonarthritic Hip Score, Hip Outcome Score–Sport Specific Subscale, and VAS ( P < .001). When outcomes were compared with those of the control group, female athletes with low BMI demonstrated lower rates of achieving the MCID for the mHHS (54.5% vs 77.4%; P = .041), PASS for the International Hip Outcome Tool–12 (45.5% vs 72.6%; P = .022), and MOIST for the VAS (31.8% vs 56.5%; P = .047). There were no other significant differences in the rate of achieving the MCID, PASS, or MOIST between the groups ( P > .05). Female athletes with low BMI also had higher rates of revision when compared with the control group (27.2% vs 10.6%; P = .049), but there were comparable return-to-sports rates (75.0% vs 74.5%; P > .05).

Conclusion:

High-level female athletes with low BMI undergoing primary hip arthroscopy for femoroacetabular impingement syndrome demonstrated significant improvement in patient-reported outcomes and acceptable rates of return to play. When compared with a control group with normal BMI, they exhibited higher rates of revision and lower rates of achieving the MCID for the mHHS, PASS for the International Hip Outcome Tool–12, and MOIST for the VAS.
Evaluation of a Diagnostic-Therapeutic Algorithm for Finger Epiphyseal Growth Plate Stress Injuries in Adolescent Climbers
Authors: Schöffl Volker , Schöffl Isabelle , Flohé Sascha , El-Sheikh Yasser , Lutter Christoph
Published: November 2021

Background:

Finger epiphyseal growth plate stress injuries are the most frequent sport-specific injuries in adolescent climbers. Definitive diagnostic and therapeutic guidelines are pending.

Purpose:

To evaluate a diagnostic-therapeutic algorithm for finger epiphyseal growth plate stress injuries in adolescent climbers.

Study Design:

Case series; Level of evidence, 4.

Methods:

On the basis of previous work on diagnostics and treatment of finger epiphyseal growth plate stress injuries (EGPIs) in adolescent climbers, we developed a new algorithm for management of these injuries, which was implemented into our clinical work. During a 4-year period, we performed a prospective multicentered analysis of our patients treated according to the algorithm. Climbing-specific background was evaluated (training years, climbing level, training methods, etc); injuries were analyzed (Salter-Harris classification and UIAA MedCom score [Union Internationale des Associations d’Alpinisme]); and treatments and outcomes were recorded: union, time to return to climbing, VAS (visual analog scale), QuickDASH (shortened version of the Disabilities of the Arm, Shoulder, and Hand), and a climbing-specific outcome score.

Results:

Within the observation period, 27 patients with 37 independent EGPIs of the fingers were recorded (mean ± SD age, 14.7 ± 1.5 years; 19 male, 8 female; 66.7% competitive athletes). Regarding maturity at time of injury, the mean age at injury did not differ by sex. Average UIAA climbing level was 9.5 ± 0.8, with 6 ± 4.6 years of climbing or bouldering and 14 ± 9.1 hours of weekly climbing-specific training volume. Among the 37 injuries there were 7 epiphyseal strains, 2 Salter-Harris I fractures, and 28 Salter-Harris III fractures (UIAA 1, n = 7; UIAA 2, n = 30). Thirty-six injuries developed through repetitive stress, while 1 had an acute onset. Twenty-eight injuries were treated nonoperatively and 9 surgically. Osseous union was achieved in all cases, and there were no recurrences. The time between the start of treatment and the return to sport was 40.1 ± 65.2 days. The climbing-specific outcome score was excellent in 34 patients and good in 3. VAS decreased from 2.3 ± 0.6 to 0.1 ± 0.4 after treatment and QuickDASH from 48.1 ± 7.9 to 28.5 ± 3.3.

Conclusion:

The proposed management algorithm led to osseous union in all cases. Effective treatment of EGPIs of the fingers may include nonsurgical or surgical intervention, depending on the time course and severity of the injury. Further awareness of EGPI is important to help prevent these injuries in the future.
Quantitative Electroencephalography (EEG) Predicting Acute Neurologic Deterioration in the Pediatric Intensive Care Unit: A Case Series
Authors: Munjal Neil K. , Bergman Ira , Scheuer Mark L. , Genovese Christopher R. , Simon Dennis W. , Patterson Christina M.
Published: November 2021

Introduction: Continuous neurologic assessment in the pediatric intensive care unit is challenging. Current electroencephalography (EEG) guidelines support monitoring status epilepticus, vasospasm detection, and cardiac arrest prognostication, but the scope of brain dysfunction in critically ill patients is larger. We explore quantitative EEG in pediatric intensive care unit patients with neurologic emergencies to identify quantitative EEG changes preceding clinical detection. Methods: From 2017 to 2020, we identified pediatric intensive care unit patients at a single quaternary children's hospital with EEG recording near or during acute neurologic deterioration. Quantitative EEG analysis was performed using Persyst P14 (Persyst Development Corporation). Included features were fast Fourier transform, asymmetry, and rhythmicity spectrograms, “from-baseline” patient-specific versions of the above features, and quantitative suppression ratio. Timing of quantitative EEG changes was determined by expert review and prespecified quantitative EEG alert thresholds. Clinical detection of neurologic deterioration was defined pre hoc and determined through electronic medical record documentation of examination change or intervention. Results: Ten patients were identified, age 23 months to 27 years, and 50% were female. Of 10 patients, 6 died, 1 had new morbidity, and 3 had good recovery; the most common cause of death was cerebral edema and herniation. The fastest changes were on “from-baseline” fast Fourier transform spectrograms, whereas persistent changes on asymmetry spectrograms and suppression ratio were most associated with morbidity and mortality. Median time from first quantitative EEG change to clinical detection was 332 minutes (interquartile range: 201-456 minutes). Conclusion: Quantitative EEG is potentially useful in earlier detection of neurologic deterioration in critically ill pediatric intensive care unit patients. Further work is required to quantify the predictive value, measure improvement in outcome, and automate the process.
Probability of Remission of the Main Epileptic Syndromes in Childhood
Authors: Ramos-Lizana Julio , Martínez-Espinosa Gema , Aguilera-López Patricia , Aguirre-Rodriguez Javier
Published: November 2021

Aim

To determine the long-term probability of remission without antiepileptic treatment of common epileptic syndromes and of children without a specific syndromic diagnosis.

Patients and methods

All children less than 14 years old with 2 or more unprovoked seizures seen at our hospital between June 1, 1994, and March 1, 2011 (n = 680), were included and prospectively followed up until August 15, 2020. Syndromic diagnosis was made retrospectively but blinded to subsequent evolution, employing the data available at 6 months after diagnosis and under predefined operational criteria.

Results

The Kaplan-Meier estimate of the probability of achieving a remission period of at least 5 years, with neither seizures nor antiepileptic treatment at 14 years was 97% for well-defined childhood epilepsy with centrotemporal spikes, 82% for uncertain childhood epilepsy with centrotemporal spikes, 85% for well-defined Panayiotopoulos syndrome, 88% for uncertain Panayiotopoulos syndrome, 93% for nonfamilial self-limited infantile epilepsy, 100% for familial self-limited infantile epilepsy, 86% for absence epilepsy, 6% for juvenile myoclonic epilepsy, 71% for cryptogenic West syndrome, 72% for patients with no associated neurologic deficits and no specific syndromic diagnosis, 65% for symptomatic West syndrome, and 40% for patients with associated neurologic deficits and no specific syndromic diagnosis.

Conclusions

The study results highlight the long-term outcomes of the main epileptic syndromes and also of the patients with no syndromic diagnosis.
Mammography Screening Disparities in Asian American Women: Findings From the California Health Interview Survey 2015–2016
Authors: Xie Hui , Li Yannan , Theodoropoulos Nickolas , Wang Qian
Published: November 2021

Purpose

To identify mammography screening prevalence and predictors in Asian American women, focusing on the potential disparities in race and its influence on screening behaviors.

Design

A secondary analysis utilized the California Health Interview Survey (CHIS) 2015–2016.

Setting

California, U.S.

Sample

Cisgender women who were non-Hispanic (NH) White, Chinese, Filipino, Vietnamese, Japanese, Korean, or “other Asian”, aged 40 or above (unweighted N=13 451).

Measures

Socioeconomics, chronic health conditions, and preventive care utilization were mesuared as potential risk factors, where up-to-date mammography screening as the outcome variable.

Analysis

Multivariable adjusted logistic regressions were generalized to identify the up-to-date mammography screening behaviors in relation to potential factors, stratified by race and ethnicity.

Results

The prevalence for up-to-date mammography screening in NH-White and Asian American women were 68.06% and 65.97%, respectively. In NH-White women, receiving an up-to-date mammogram was associated with age, birthplace, smoking status, diabetes, hypertension, health insurance coverage, and a preventive care visit in the past 12 months, whereas only age and a preventive care visit were significant predictors in Asian women.

Conclusions

The findings indicate that utilization disparities exist in mammogram in relation to socioeconomics, chronic health conditions, preventive care utilization, when comparing between race and ethnicity. Asian American women with borderline hypertension and no preventive care visits may require more public health outreach and cancer education.
Exploring the link between student placement learning in business organizations and self-employment preparatory behaviours
Authors: Okolie Ugochukwu Chinonso , Elom Chinyere O. , Onajite Godwin O. , Abonyi Sunday Okechukwu , Igwe Paul A.
Published: November 2021

This study draws on social cognitive career theory to test a moderated mediation model of self-employment preparatory behaviours in university students undertaking placement learning in a business organization (PLBO). Using time-lag data from 337 university students undertaking work placement in 123 business organizations, the study hypotheses were tested using PROCESS Macro 3.5. The results revealed that PLBO significantly influenced student self-employment self-efficacy, self-employment outcome expectations and self-employment preparatory behaviours. Also, self-employment self-efficacy and self-employment outcome expectations mediated the relationship between work placement learning and self-employment preparatory behaviours. However, placement supervisor support interacted with PLBO such that greater support from placement supervisors contributed to stronger self-employment preparatory behaviours. The placement learning supervisor support moderated the indirect effect of PLBO on self-employment preparatory behaviours via self-employment self-efficacy and self-employment outcome expectations at all levels (−1SD, Mean and +1SD).
Frontal QRS-T angle as a predictive marker for myocardial damage in acute carbon monoxide poisoning
Authors: Tekin Yusuf K , Tekin Gülaçan , Nur Naim , Korkmaz İlhan , Yurtbay Sefa
Published: November 2021

Introduction

The present study was undertaken to investigate the prognostic value of the frontal QRS-T angle associated with adverse cardiac outcomes in patients with carbon monoxide (CO) poisoning in early stages in the emergency department.

Materials and methods

The data of 212 patients with CO poisoning who were admitted to the ED between January 2010 and May 2020 were retrospectively analyzed. The frontal QRS-T angle was obtained from the automatic reports of the EKG device.

Results

Compared to patients without myocardial damage, among patients with myocardial damage, statistically high creatinine, creatine kinase MB, cardiac troponin I, and frontal QRS-T angle values were found ( p < 0.001 for all parameters), while the saturation of arterial blood pH and arterial oxygen values were found to be lower ( p = 0.002 and p < 0.001, respectively). The frontal QRS-T angle values were correlated with creatine kinase, creatine kinase-MB, cardiac troponin I, and oxygen saturation (SpO2) in arterial blood (r = 0. 232, p = 0.001; r = 0. 253, p = < 0.001; r = 0. 389, p = < 0.001; r = −0. 198, p = 0.004, respectively). The optimum cut-off value of the frontal QRS-T angle was found to be 44.5 (area under the curve: 0.901, 95% confidence interval: 0.814–0.988, sensitivity: 87%, specificity: 84%).

Conclusions

The frontal QRS-T angle, a simple and inexpensive parameter that can be easily obtained from 12-lead surface electrocardiography, can be used as an early indicator in the detection of myocardial damage in patients with CO poisoning.
Thymoquinone ameliorates bleomycin-induced reproductive toxicity in male Balb/c mice
Authors: Yaghutian Nezhad L , Mohseni Kouchesfahani H , Alaee S , Bakhtari A
Published: November 2021

Bleomycin (BL) is a powerful chemotherapy drug that has devastating effects on spermatogenic function and may make cancer survivors at risk of infertility. Protective effects of thymoquinone (TQ), a phytochemical compound with antioxidant and anticancer influences, were investigated on sperm parameters, testicular structures, and sexual hormones in BL-treated mice. Forty-eight adult male Balb/c mice were randomly divided into six groups. Control group received normal saline; BL group received 10 mg/kg BL; TQ7.5 group received 7.5 mg/kg TQ; TQ15 group received 15 mg/kg TQ; BL+TQ7.5 group received 10 mg/kg BL and 7.5 mg/kg TQ; BL + TQ15 group received 10 mg/kg BL and 15 mg/kg TQ. BL was intraperitoneally used every day through 35 days, and TQ was intraperitoneally injected 3 days before administration of BL and continued twice per week for 35 days. Results showed that BL significantly decreased count, viability, morphology, maturity, and progressive movement of sperm, testosterone, seminiferous tubule diameters, the ratio of testis weight to body weight, number of spermatogonia, spermatocytes, spermatids, and Sertoli cells per tubule, and expression of Bcl2l1 and Bcl2l1/Bax ratio, and increased the non-progressive movement and immotile sperm, intermediate and immature sperm, LH, FSH, and malondialdehyde levels, and tunica albuginea thickness compared to the control group ( p < .05). TQ at a level of 7.5 mg/kg ameliorated BL-induced toxicity on measured parameters and returned most of them to the level of the control group. These data suggested TQ in a dose-dependent manner may have positive effects on BL-induced toxicity of the testis in mice model.
Displacement, time and resistance: The role of waiting in facilitating occupations led by internally displaced persons in Colombia
Authors: Schouw Iversen Karen
Published: November 2021

This article contributes to the existing literature on the politics of waiting by discussing occupations led by internally displaced persons (IDPs) in Colombia. This literature has emphasised both the power that waiting frequently entails and, increasingly, the agency it can comprise. Yet less has been said about the potential role of waiting in generating resistance. Drawing on a Foucauldian understanding of power as intimately tied to resistance, this article explores how waiting can, in some instances, produce resistance. It uses fieldwork conducted in Bogotá, Colombia, between October 2017 and August 2018, including ethnographic observations and 120 interviews conducted with IDPs and state officials, to explore the centrality of waiting to IDPs’ experiences of displacement in Colombia. Contrary to those who would argue that such waiting encourages passivity, the article draws on a discussion of a two-year-long occupation by IDPs in Bogotá to argue that the long waiting periods facing the occupation’s participants prior to partaking in it were instrumental to facilitating the occupation. Waiting enabled the occupation in two major ways: by bringing together a group of people who would not have met had they not been forced to spend prolonged time together in close quarters and by constituting a key source of frustration motivating the occupation.
The Role and Mechanism of Exosomes from Umbilical Cord Mesenchymal Stem Cells in Inducing Osteogenesis and Preventing Osteoporosis
Authors: Yahao Ge , Xinjia Wang
Published: November 2021

Mesenchymal stem cell (MSC) exosomes promote tissue regeneration and repair, and thus might be used to treat many diseases; however, the influence of microenvironmental conditions on exosomes remains unclear. The present study aimed to analyze the effect of osteogenic induction on the functions of human umbilical cord MSC (HucMSC)-derived exosomes. Exosomes from standardized stem cell culture (Exo1) and osteogenic differentiation-exosomes (Exo2) were co-cultured with osteoblasts, separately. Cell counting kit-8 assays, alkaline phosphatase and alizarin red staining were used to observe the exosomes’ effects on osteoblast proliferation and differentiation. The levels of osteogenic differentiation-related proteins were analyzed using western blotting. Estrogen-deficient osteoporosis model mice were established, and treated with the two exosome preparations. Micro-computed tomography and hematoxylin and eosin staining were performed after 6 weeks. MicroRNAs in Exo1 and Exo2 were sequenced and analyzed using bioinformatic analyses. Compared with Exo1 group, Exo2 had a stronger osteogenic differentiation promoting effect, but a weaker proliferation promoting effect. In ovariectomy-induced osteoporosis mice, both Exo1 and Exo2 improved the tibial density and reversed osteoporosis in vivo. High-throughput microRNA sequencing identified 221 differentially expressed microRNAs in HucMSC-derived exosomes upon osteogenic induction as compared with the untreated control group. Importantly, we found that 41 of these microRNAs are potentially critical for MSC-secreted exosomes during osteogenic induction. Mechanistically, exosomal miRNAs derived from osteogenic induced-HucMSCs are involved in bone development and differentiation, such as osteoclast differentiation and the MAPK signaling pathway. The expression of hsa-mir-2110 and hsa-mir-328-3p gradually increased with prolonged osteogenic differentiation and regulated target genes associated with bone differentiation, suggesting that they are probably the most important osteogenesis regulatory microRNAs in exosomes. In conclusion, we examined the contribution of osteogenic induction to the function of exosomes secreted by HucMSCs following osteogenic differentiation in vitro and in vivo, and reveal the underlying molecular mechanisms of exosome action during osteoporosis.
Dynamic mechanical analysis of nylon 6 fiber-reinforced acrylonitrile butadiene rubber composites
Authors: Rajesh C , Divia P , Dinooplal S , Unnikrishnan G , Purushothaman E
Published: November 2021

Dynamic mechanical properties of polymeric materials are of direct relevance to a range of unique polymer applications. The aim of the study is to investigate the dynamic mechanical properties of composites of short nylon 6 fiber with acrylonitrile butadiene rubber (NBR). The storage modulus (G′), loss modulus (G″), and the damping factor (tan δ) have been analyzed with reference to the effects of fiber loading, curing systems, and bonding agents over a range of temperature and at varying frequencies. The storage modulus increases with increment in fiber loading, whereas loss modulus and damping factor decrease. The glass transition temperature shifts to higher temperature upon increment in fiber loading. Dicumyl peroxide (DCP)–cured composites show higher storage modulus and lower damping than the corresponding sulfur-cured one. The addition of hexa-resorcinol and phthalic anhydride as bonding agents enhances the dynamic mechanical properties of the composites. The experimental results have been evaluated by comparing with Einstein, Guth, and Nielsen models.
Mobility as Rhizome and Becoming: Experiences of Vietnamese Women in Crossing Borders to do Doctorates
Authors: Pham Xuan , Bright David
Published: November 2021

The purpose of this paper is to unpack the meanings and implications of mobility through the experiences of a group of Vietnamese women who decided to do doctorates in Australia. Drawing on the Deleuzian concepts of rhizome and becoming, our analysis of interview data suggests that mobility is made of multiple connections and is in constant movement, extending often reductive “push-pull” discussions of academic mobility. Each aspect shaping mobility connects to another that is multiscalar and multitemporal, where family, education ideologies, gender norms, economic globalization, neoliberalization within higher education, and the histories and biographies of mobile people come together. Power relations are immanent within structures associated with these connections and the women and mobility come together to create aspirations for educational, professional, and personal becoming. The paper offers a more nuanced understanding of international academic mobility rather than relying on economic perspectives and invites innovative approaches in supporting international doctoral students.
Academic Careers in Transnational Higher Education: The Rewards and Challenges of Teaching at International Branch Campuses
Authors: Wilkins Stephen , Annabi Carrie Amani
Published: November 2021

This research investigates the attitudes, working conditions, experiences, and job satisfaction of academic staff employed at offshore campuses. An online survey questionnaire was completed by 72 academic staff in 10 different countries, which included China, Malaysia, Qatar, the UAE, and Vietnam. It was found that the desire for adventure and travel, and to experience a foreign culture, were the most popular motivations for working at an offshore campus. Common challenges and disadvantages of teaching at an offshore campus are the lack of job security, support for research, academic freedom, and opportunities for development and advancement. However, such academics often have motivated students, smaller class sizes, greater autonomy at work, fewer meetings, higher disposable income, and less of the ‘publish or perish’ culture. Almost three-quarters of our research participants believe that it is possible to have an attractive career teaching in transnational education, at offshore campuses.
Effect of Race/ethnicity, Insurance Status, and Area Deprivation on Hip Fracture Outcomes Among Older Adults in the United States
Authors: Lee Chiyoung , McConnell Eleanor Schildwachter , Wei Sijia , Xue Tingzhong (Michelle) , Tsumura Hideyo , Pan Wei
Published: November 2021

This retrospective cohort study used electronic health records to explore the effect of race/ethnicity, insurance status, and area deprivation on post-discharge outcomes in older patients undergoing hip fracture surgery between 2015 and 2018 ( N = 1,150). Inverse probability of treatment weight-adjusted regression analysis was used to identify the effects of the predictors on outcomes. White patients had higher 90- and 365-day readmission risks than Black patients and higher all-period readmissions than the Other racial/ethnic (Hispanic, Asian, American Indian, and Multicultural) group ( p < .000). Black patients had a higher risk of 30- and 90-day readmission than the Other racial/ethnic group ( p < .000). Readmission risk across 1-year follow-up was generally higher among patients from less deprived areas than more deprived areas ( p < .05). The 90- and 365-day mortality risk was lower for patients from less deprived areas (vs. more deprived areas) and patients with Medicare Advantage (vs. Medicare), respectively ( p < .05). Our findings can guide efforts to identify patients for additional post-discharge support. Nevertheless, the findings regarding readmission risks contrast with previous knowledge and thus require more validation studies.
Research on a collocation approach and three metaheuristic techniques based on MVO, MFO, and WOA for optimal control of fractional differential equation
Authors: Ebrahimzadeh Asiyeh , Khanduzi Raheleh , A Beik Samaneh P , Baleanu Dumitru
Published: November 2021

Exploiting a comprehensive mathematical model for a class of systems governed by fractional optimal control problems is the significant focal point of the current paper. The efficiency index is a function of both control and state variables and the dynamic control system relies on Caputo fractional derivatives. The attributes of Bernoulli polynomials and their operational matrices of fractional Riemann–Liouville integrations are applied to convert the optimization problem to the nonlinear programing problem. Executing multi-verse optimizer, moth-flame optimization, and whale optimization algorithm terminate to the most excellent solution of fractional optimal control problems. A study on the advantage and performance between these approaches is analyzed by some examples. Comprehensive analysis ascertains that moth-flame optimization significantly solves the example. Furthermore, the privilege and advantage of preference with its accuracy are numerically indicated. Finally, results demonstrate that the objective function value gained by moth-flame optimization in comparison with other algorithms effectively decreased.
The Mediating Role of Moral Absolutism Between the “Binding Moral Foundations” and Sexist Attitudes: A Path That May Lead to Intimate Partner Violence
Authors: Vecina María L. , Chacón José C. , Piñuela Raul
Published: November 2021

The binding foundations (loyalty, authority, and purity) constitute adaptive mechanisms for preserving groups’ interests. However, they have also been related to intergroup prejudice and violence. We show that the known relationship between the binding foundations and sexist attitudes is mediated by moral absolutism, a variable that reflects the degree to which people believe that their own definition of morality is objectively correct. Two different samples are used: a conventional one (Study 1, N  =  321), and a forensic one at the beginning ( T1) and at the end ( T2) of court-mandated psychological therapy (Study 2, N  =  354; N  =  327).
The End of the Right to the City: A Radical-Cooperative View
Authors: Althorpe Caleb , Horak Martin
Published: November 2021

Is the Right to the City (RTTC) still a useful framework for a transformative urban politics? Given recent scholarly criticism of its real-world applications and appropriations, in this paper, we argue that the transformative promise in the RTTC lies beyond its role as a framework for oppositional struggle, and in its normative ends. Building upon Henri Lefebvre's original writing on the subject, we develop a “radical-cooperative” conception of the RTTC. Such a view, which is grounded in the lived experiences of the current city, envisions an urban society in which inhabitants can pursue their material and social needs through self-governed cooperation across social difference. Growing and diversifying spaces and sectors of urban life that are decoupled from global capitalism are, we argue, necessary to create space for this inclusionary politics. While grassroots action is essential to this process, so is multi-scalar support from the state.
Extraction and characterization of arabinoxylans obtained from nixtamalized brewers’ spent grains
Authors: Martínez-Encinas Efrén G , Carvajal-Millán Elizabeth , Calderón de la Barca Ana M , Rascón-Chu Agustín , Martínez-Porchas Marcel , Márquez-Escalante Jorge A , Islas-Rubio Alma R
Published: November 2021

The processes to obtain value-added products from brewers’ spent grain, a contaminant industrial waste, require alkaline non-ecofriendly pre-treatments. The arabinoxylans from brewers’ spent grain were extracted by nixtamalization evaluating the extraction procedure, antioxidant capacity and molecular characteristics. The best arabinoxylans yields were those extracted with CaO at 100 °C and 25 °C (6.43% and 3.37%, respectively). The antioxidant capacity by 2,2-diphenyl-1-picrylhydrazyl assay of the arabinoxylans after thermal treatment and additional arabinoxylans after thermal treatment proteolysis were 434 and 118 mg TE/g, while by 2,20′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt assay the value was similar (380 μmol TE/g). The intrinsic viscosities and viscosimetric molecular weights were 69 mL/g and 13 kDa for arabinoxylans after thermal treatment, and 15 mL/g and 1.6 kDa for arabinoxylans after thermal treatment proteolysis, respectively. The protein and lignin contents were 3.1% and 6.4% for arabinoxylans after thermal treatment and, 0.9% and 4.6% for arabinoxylans after thermal treatment proteolysis, while their arabinose: xylose ratios were 0.39 and 0.36, with ferulic acid contents of 0.63 and 0.14 mg/g, respectively. Both products of arabinoxylans were molecularly identical by Fourier transform infra-red. Although the purity of the extracted arabinoxylans was improved with proteolysis, their intrinsic viscosity and viscosimetric molecular weight were affected. The extraction of arabinoxylans from brewers’ spent grain by CaO nixtamalization alone or after additional proteolysis was successful to obtain purity and good antioxidant capacity.
US Tobacco 21 is Paving the Way for a Tobacco Endgame
Authors: Kim Samuel C J , Martinez Jason E , Liu Yanjun , Friedman Theodore C
Published: November 2021

The battle against tobacco usage is being fought on all fronts. On December 19, 2019, a measure to raise the minimum age to buy tobacco products to 21 from 18 was passed by the United States Congress and signed by President Donald Trump. This instated banning the sale of all tobacco products and electronic cigarettes to anyone in the US under the age of 21. This follows the raising of the age to buy tobacco in California to 21 in 2016. According to the California Tobacco Control Program: in 2016, roughly 10% of high-school students were smoking cigarettes, but by 2018, only 2%. The percentage of retailers selling tobacco to underaged youth dropped dramatically. These data show that the CA Tobacco 21 law was effective in decreasing the obtainability and usage of tobacco by youth. We expect that US Tobacco 21 will be similarly effective in reducing tobacco use by youth leading to less tobacco addiction in the US.
Perimyocarditis Following COVID-19 Vaccination
Authors: Tinoco Mariana , Leite Sérgio , Faria Bebiana , Cardoso Sara , Von Hafe Pedro , Dias Geraldo , Cardoso Filipa , Pereira Tamara , Machado Inocência , Lourenço António
Published: November 2021

A 39-year-old male was admitted in the emergency room with chest pain. He had been given the second dose of Pfizer–BioNTech COVID-19 vaccine 3 days before. The patient denied taking any other medication beyond the usual. He didn’t feel sick in the previous days/weeks. Laboratory studies revealed elevated serum levels of troponin and C-reactive protein. An autoantibody screen and a serologic panel to detect common viruses were negative. A cardiac MRI showed myocardial edema/inflammation and confirmed the diagnosis of perimyocarditis which was considered to be a consequence of COVID-19 vaccination. Physicians should be aware of the possibility of cardiovascular complications after COVID-19 vaccination.
Tell me your story: Branding destinations through residents’ (place) stories
Authors: Hay Nicole A. , Chien P. Monica , Ruhanen Lisa
Published: November 2021

Concerns have been raised that destination branding often overlooks the destination's internal stakeholders, and in some cases, has resulted in a brand identity that does not reflect the meanings and emotions that residents attach to places. Consequently, scholars have advocated for a more participatory approach to destination branding in which residents’ sense of place can be acknowledged, represented, and operationalized. This paper synthesizes these arguments and demonstrates that such an approach can be achieved by embracing residents’ place stories. Through storytelling, residents construe different facets of the place identity that is the foundation of destination brand identity. Hence, the purpose of this paper is to investigate the role, constituents, and effects of storytelling in destination branding, particularly exploring whose stories should be told and how these stories should be conveyed. In doing so, a participatory approach to destination branding is presented that employs residents’ place stories as a genuine form of participation in the destination branding process. Lastly, an agenda for future research is proposed, and practical implications for destination marketing practice are discussed.
Convivial reflexivity in the changing city – a tale of hospitality or hostility?
Authors: Koulaxi Afroditi-Maria
Published: November 2021

The article interrogates whether citizens’ (embodied) encounters with migrant populations (newcomers and settled) enable or hinder convivial reflexivity in a multicultural city of compounded crises. Convivial reflexivity refers to the embodied process of identity-making that is rooted in the context of everyday life and emerges at the juncture of embodied encounters with the Other and the intense mediation of migration that shapes citizens’ perceptions and practices. The article draws on a four-month intense ethnographic study in an Athenian neighbourhood and reveals how, even in a very tense environment of crises and intensified racism, everyday encounters in the city could mediate class solidarities and support the emergence of networked commons against national and racial hierarchies. The article aims to move beyond claims of conviviality as a natural outcome of urban encounters, and instead to reveal a convivial reflexivity that understands urban encounters as an assemblage of cognition, affect and embodiment.
Kettil Bruun is more relevant than ever
Authors: Hellman Matilda
Published: November 2021

Kettil Bruun is best known for the total consumption model introduced in 1975 in the collective work “Alcohol control policy in public health perspective”. There were three tracks in particular that led Bruun's research towards the total consumption model: research on the distribution of power, research on international drug policies, and his contributions to criminology and social policy. Kettil Bruun’s lifework shows that the innovation, intersectionality, and synergy which are now rehearsed in pompous research strategies were a non-question 40 years ago. These aspects were a natural part of the scientific pursuit of answers. Maybe in a much more modest and homemade form, but all the more import in terms of applicability at the general level of principle.
The associations of information system’s support and nurses' documentation competence with the detection of documentation-related errors: Results from a nationwide survey
Authors: Kaihlanen Anu-Marja , Gluschkoff Kia , Saranto Kaija , Kinnunen Ulla-Mari , Heponiemi Tarja
Published: November 2021

The use of information systems and electronic documentation has become a central part of a nurse’s work, and it is expected to increase the quality of documentation and patient safety. However, errors related to documentation have been identified as a significant risk for the quality and safety of care. This study examined whether information system’s support for documentation and nurses' documentation competence are associated with how frequently nurses detect documentation-related errors that have caused an adverse event. A nationwide survey was conducted in 2020, and a total of 3610 nurses participated. Results from linear regression analyses showed that high documentation support from the information system and high documentation competence were associated with fewer detected documentation-related errors. Nurses with low documentation support from the system and low documentation competence detected the most errors. The results highlight the need to develop electronic health record functions in a way that they better support accurate documentation. Furthermore, organisations should invest in ensuring the documentation skills of nurses and providing appropriate training.
Introducing COMEPELDA: Comprehensive European Parliament electoral data covering rules, parties and candidates
Authors: Däubler Thomas , Chiru Mihail , Hermansen Silje SL
Published: November 2021

We introduce a new collection of data that consolidates information on European Parliament elections into one comprehensive source. It provides information on formal electoral rules as well as national-level and district-level election results for parties and individual politicians (including full candidate lists). The use of existing and new key variables makes it easy to link the data across the different units of observation (country, party, candidate, member of parliament) and join them with external information. Currently, the data cover four elections (1999–2014). Among other aspects, the collection should facilitate research on the European Parliament's allegedly weak electoral connection. In this article, we outline the main features of the datasets, describe patterns of intra-party competition and preference voting and conduct exploratory analyses of individual-level changes in list positions.
CTEN Inhibits Tumor Angiogenesis and Growth by Targeting VEGFA Through Down-Regulation of β-Catenin in Breast Cancer
Authors: Lu Xiangdong , Zhou Bin , Cao Minmin , Shao Qin , Pan Yukai , Zhao Tao
Published: November 2021

C-terminal tensin-like (CTEN) belongs to the tensin gene family, which encodes proteins that localize to focal adhesions and modulate integrin function. Accumulating studies have reported that CTEN expression can be upregulated or downregulated in different types of cancers, suggesting that CTEN has both oncogenic and tumor suppressor functions. In this study, by analyzing the expression level of CTEN in the human breast cancer (BRCA) samples from the clinically annotated genomic database, The Cancer Genome Atlas, we found that CTEN was downregulated in different BRCA subclasses, including luminal, human epidermal growth factor receptor 2 positive and triple-negative BRCA. Consistently, the protein level of CTEN was also reduced in BRCA based on the Proteomic Tumor Analysis Consortium. In contrast, vascular endothelial growth factor A (VEGFA), a signal protein that stimulates the formation of blood vessels, was upregulated in BRCA. CTEN overexpression in human umbilical vein endothelial cells and MCF7 significantly suppressed the expression of VEGFA, inhibited cell proliferation, migration, and tube formation in vitro. Mechanistically, CTEN bind to casitas B-lineage lymphoma (c-Cbl), an E3 ubiquitin-protein ligase, and decreased the β-catenin expression. In turn, the downregulation of β-catenin reduced the expression of VEGFA. Rescuing β-catenin expression effectively ameliorated the effect of CTEN overexpression in cell proliferation, migration, and tube formation. In conclusion, CTEN inhibited tumor angiogenesis by targeting VEGFA through c-Cbl-mediated down-regulation of β-catenin and may serve as a tumor suppressor in BRCA.
Quantitative MRI Differences Between Early versus Late Onset Alzheimer’s Disease
Authors: Meysami Somayeh , Raji Cyrus A. , Merrill David A. , Porter Verna R. , Mendez Mario F.
Published: November 2021

Investigators report greater parietal tau deposition and alternate frontoparietal network involvement in early onset Alzheimer’s Disease (EOAD) with onset <65 years as compared with typical late onset AD (LOAD). To determine whether clinical brain MRI volumes reflect these differences in EOAD compared with LOAD. This study investigated the clinical MRI scans of 45 persons with Clinically Probable AD with onset <65 years, and compared them to 32 with Clinically Probable AD with onset ≥65 years. Brain volumes on their T1 MRI scans were quantified with a volumetric program. Receiver operating curve analyses were performed. Persons with EOAD had significantly smaller parietal lobes (volumetric percentiles) than LOAD. Late onset Alzheimer’s Disease had a smaller left putamen and hippocampus. Area Under the Curve was 96 .5% with brain region delineation of EOAD compared to LOAD. This study indicates parietal atrophy less than 30% of normal on clinical MRI scans is suggestive of EOAD compared to LOAD.
From the Editors
Authors: Ray Rashawn , Rojas Fabio
Published: November 2021

Contexts editors Rashawn Ray and Fabio Rojas introduce the fall issue on transforming the criminal justice system.
Reimagining Policing in America
Authors: Neily Clark
Published: November 2021

Police killings have increased over 100% in the past two decades. Black people, along with American Indians and Latinx communities (and some Asian and Pacific Islander communities), are more likely to have police force used on them relative to whites. This article aims to provide policy recommendations that inform reforms toward police accountability, improved training, and a police culture that protects citizens. We focus on short-, medium-, and long-term solutions for reimagining law enforcement to reduce officer-involved shootings, racial disparities in use of force, mental health issues among officers, and problematic officers who rotten the tree of law enforcement. We focus acutely on the need to abolish qualified immunity with the longterm change of transforming police culture itself to better protect civilians and police who approach their jobs with ethical respect.
Reimagining Pretrial & Sentencing
Authors: Lattimore Pamela K. , Spohn Cassia , Demichele Matthew
Published: November 2021

In this article, we discuss the evolution of criminal justice reform efforts focused on pretrial and sentencing policies and practices that resulted in unprecedented rates of incarceration. There is an urgent need to identify a strategy of pretrial justice and sentencing that will reduce crime and victimization, ameliorate unwarranted disparities, and reclaim human capital currently lost to incarceration. A discussion of proposed policy reforms should begin by first identifying the costs incurred by pretrial decisions (and across further decision points in the justice system) on both the system and the collateral costs to the detained, their families and their communities. In the short-term, jurisdictions should reconsider probation and parole policies and practices that contribute to mass incarceration. Mid-term improvements require inter-agency approaches by law enforcement, prosecutors, and the courts to institute alternatives to incarceration and collaborate with health and community organizations to address underlying issues that lead to local justice system intervention. Importantly, what we highlight is the need for a long-term approach designed to slow the flow of individuals into jails and prisons and to reduce the lengths of sentences they are serving.
Changing Prisons to Help People Change
Authors: Visher Christy , Eason John M.
Published: November 2021

It is important to consider the conditions of prison life in understanding how individuals rejoin society at the conclusion of their sentence. Cognitive Behavioral Therapy (CBT) is an evidence-based approach that promotes new ways of thinking and behaving for both incarcerated persons and correctional staff that will better prepare returning citizens to be valuable community members. We consider that “since criminal behavior is driven partly by certain thinking patterns that predispose individuals to commit crimes or engage in illegal activities, the widespread implementation of CBT [and immersive cognitive communities] as part of correctional programming could lead to fewer re-arrests and lower likelihood of reincarceration.” This article includes short, intermediate, and long-term policy and practice recommendations to begin implementing this model, beginning with funding to support the implementation of Cognitive Communities, re-branding prisons to focus on rehabilitation, and finally making the reduction of prison-sentencing through shorter prison terms and more reliance on community sanctions a long-term policy goal in the U.S.
Women of Color’s Reproductive Perils Reproduced
Authors: Casanova Felicia O.
Published: November 2021

Last year, women detained at a Georgia ICE detention center accused a doctor of conducting various hysterectomies that were unwanted or without consent. These allegations echo past sterilization abuses on women of color and challenge us to recall some historical accounts of women's sterilization in Black and Brown communities in America, including eugenics programs targeting poor women of color. When particularly examining the women's reproductive health in the carceral system, there are direct conflicts between providing proper healthcare and human rights protections and the economic interests of privately operated detention centers. This essay reviews these concerns and recommends changes from government and carceral facilities.
The Social Roots of Sexual Violence
Authors: Drotning Kelsey J.
Published: November 2021

In their book, Sexual Citizens: A Landmark Study of Sex, Power, and Assault on Campus, Jennifer S. Hirsch and Shamus Khan seek to understand why campus sexual assault happens and what can be done to prevent it in the future by identifying its social roots. The book approaches sexual assault from an ecological public health perspective, but I think at its core, I think it is also an argument for dismantling power disparities within institutions.