bluuebunny/crossref_metadata_2025 huggingface dataset:
DETERMINAN PRAKTIK PERSONAL HYGIENE MAHASISWA UNIVERSITAS DIPONEGORO SEBAGAI BENTUK PENCEGAHAN DALAM SITUASI PANDEMI COVID-19
Authors: Esthevyani Nadira , Darundiati Yusniar Hanani , Wahyuningsih Nur Endah
Published: June 2021

COVID-19 telah ditetapkan sebagai pandemi pada skala global. Kurangnya menjaga kualitas personal hygiene dapat menjadi penyebab rentannya penularan COVID-19, hal ini menjadi perhatian terutama bagi mahasiswa perantauan yang harus melakukan karantina baik di indekos, asrama, atau rumah kontrakan. Penelitian ini bertujuan untuk mengetahui determinan praktik personal hygiene mahasiswa Universitas Diponegoro sebagai bentuk pencegahan dalam situasi pandemi COVID-19. Penelitian ini berjenis kuantitatif dengan observasional analitik menggunakan pendekatan cross-sectional. Penentuan sampel menggunakan proportional random sampling pada 442 responden dengan pengambilan data penelitian didapat melalui kuesioner online dan dianalisa secara univariat dan bivariat. Responden paling banyak berjenis kelamin perempuan (71,7%), memiliki pengetahuan tentang praktik personal hygiene yang kurang baik (27,4%), memiliki sikap tentang praktik personal hygiene yang kurang baik (45,2%), memiliki lingkungan sosial yang tidak mendukung (55,2%), tidak dapat menjangkau akses informasi (46,2%), dan memiliki praktik personal hygiene yang kurang baik (40,7%). Ada hubungan antara jenis kelamin (p=0,001), sikap tentang praktik personal hygiene (p=0,001), dukungan sosial (p=0,001), dan akses informasi (p=0,001) dengan praktik personal hygiene responden. Praktik personal hygiene kurang baik pada mahasiswa Universitas Diponegoro lebih banyak ditemukan pada mahasiswa berjenis kelamin laki-laki dan sikap tentang praktik personal hygiene yang kurang baik
Juan Valverde de Amusco in the medicine of the spanish Renaissance
Authors: Burgos Lázaro R. , Burgos Frías N. , Blázquez González JA , Gilsanz Rodríguez F. , Téllez de Peralta G. , Rodríguez Montes JA
Published: June 2021

The anatomical works of Juan Valverde de Amusco History of the composition of the human body, and De humani corporis fabrica by Andrés Vesalio were the two main references for anatomists and surgeons during the Renaissance.
Valverde’s work is the result of the study on the corpse. It is composed of seven books and follows a descending architectural order, from head to toe, in the same way as Vesalius’ text. Valverde was accused of plagiarizing Vesalio’s De humani corporis fabrica, the criticisms came from northern Europe -Vesalio was born in Brussels-, the arguments used were lacking in solidity and more interested than with a scientific basis.
It is paradoxical to see that Valverde’s work was better known in Europe than in Spain, despite being written in Spanish. The promulgation of the Real Pragmatic by Felipe II that prohibited studying in foreign universities contributed to this ignorance.
Boletín Económico Regional : Nororiente, I trimestre de 2021
Authors:   Sección de Sucursales Regionales de Estudios Económicos
Published: June 2021

Durante el primer trimestre de 2021, pese al impacto que generó el segundo pico de contagios del Covid-19 en enero, distintos sectores económicos de la región continuaron con un crecimiento anual mostrando un proceso de recuperación, el cual estuvo impulsado particularmente por el resultado de marzo, dado el efecto base comparativa con igual mes del año anterior, cuando se iniciaron las medidas de cuarentena estricta. La mayoría de los indicadores disponibles sobre la demanda interna y la producción, evidenciaron en el trimestre variaciones positivas. La inflación continuó en niveles inferiores a la meta fijada por el Banco de la República, y en el mercado laboral, se acentuó la informalidad en Cúcuta y hubo aumento en la tasa de desempleo en todas las ciudades de la región.
The religiosity of Hijrah adolescence in Muslimah Aceh Fillah Community Aceh Tamiang Indonesia
Authors: Afriyanti Nadya , Surya Dedy
Published: June 2021

In the influx of hedonism and consumptive culture due to the development of communication and information technology, extraordinary migration flows from the young generation of Indonesia. This study aims at the religiosity of adolescents experienced by adolescents migrating through 5 dimensions of religiosity: experiential, ritualistic, ideological, intellectual, and consequential. This study involved 5 Muslimah Aceh Fillah members selected by purposive sampling techniques using a qualitative approach. In-depth interview techniques and participatory observations obtained the data. In addition to engaging its members, the researchers also took parental data from the study subjects to get a comprehensive picture. Then, the data is analyzed through 3 stages: data reduction, data presentation, and conclusion. The results showed that the religiosity of hijra adolescents is expressed in various dimensions. The most significant change felt by community members is thought in an intellectual dimension that implies a difference in the other aspect of religiosity.
Intercultural and interethnic dialogue as a condition and guarantee of stable development
Authors:   M. Ulugbek National Universityof Uzbekistan, Shermukhamedova N.A. , Korganova S.S. ,   M. Auezov South Kazakhstan University
Published: June 2021

In the era of global changes caused by innovative technologies and values, the problem of intercultural and interethnic dialogue of ethnic communities is of particular relevance. Interethnic dialogue is the achievement of a high culture of different peoples and ethnic groups in the name of preserving peace on Earth. Globalization has contributed to the parallel development of conflicting trends in ethnic and national cultures. It is globalization in the sphere of spiritual culture that means the complete displacement of all other cultures by mass culture. Mass culture becomes the main obstacle to the preservation of national culture and is widely spread with the development of communication systems. The influence of mass culture on the national culture and its dominance is observed in the traditional culture of each nation.Ethnic culture is a prerequisite of modernization, which at the same time retains elements of the traditions of the ethnic group. National culture has a special psychological appeal for its representatives, which is manifested in the preservation of national identity and meets the emotional and spiritual needs of a person and is therefore necessary. The development of national cultures does not negate universal values, and this in turn implies mutually beneficial intercultural and interethnic development. Thus, this article examines the features of intercultural dialogue in the era of globalization and some trends in interethnic relations in Uzbekistan.
Experience of application of fermented products based on goat’s milk in baby food
Authors:   LLP «Kazakh academy of nutrition», Sinyavskiy Yu.A. , Nurushev M.Zh. ,   L.N. Gumilyov Eurasian National University, Mukhambetova E.S. ,   LLP «Kazakh academy of nutrition», Kenzhebaeva S.K. ,   STI «Specialized Orphanage», Smagulova A.N. ,   STI «Specialized Orphanage», Nadirova S.A. ,   LLP «Kazakh academy of nutrition», Berdygaliyev A.B. ,   LLP «Kazakh academy of nutrition», Deripaskina Ye.A. ,   LLP «Kazakh academy of nutrition», Barmak S.M. ,   LLP «Kazakh academy of nutrition»
Published: June 2021

The need to include goat milk and products based on it in the diet of children of all age groups is justified by the high nutritional and biological value, low allergenicity and nutritional value. The aim of the study was to evaluate the clinical efficacy fermented milk products based on goat’s milk on children’s health. A study of the effect of fermented milk products based on goat’s milk on the skin condition, fecal microbiology, blood biochemical parameters, the activity of transaminases ALT, AST, total bilirubin, urea, total protein, total iron-binding capacity of blood serum, the level of albumin, glucose, indicators of the cellular and humoral links immunity, as well as the level of immunoglobulin E with a two-month consumption of products by 30 children of the specialized orphanage in Nur-Sultan, aged 8 months to 4 years. The analysis of the obtained results indicates that after 60-day intake of fermented milk products by children of a specialized orphanage in NurSultan, there was a positive trend in changes in the skin condition, functional disorders of the digestive system were leveled, and dysbiotic disorders of the intestine decreased. On the part of blood biochemical parameters, a positive dynamic was also noted in the change in the level of hemoglobin, erythrocytes, hematocrit, levels of protein, calcium and iron, as well as hepatic transaminases. The level of immunoglobulin E in the blood decreased, indicating a decrease in the allergic load on the body, the indicators of the cellular link of immunity normalized.
Evaluation of Nutraceutical content and topical Anti-inflammatory Activities of Turraea vogelii Hook F. Ex Benth (Meliaceae)
Authors:   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria., Olumoh-Abdul Hidayah Ayodeji , Ayanniyi Rashidat Oluwafunke ,   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria., Ojuade Fatimoh Idowu ,   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria., Agbana Remilekun Justina ,   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria.
Published: June 2021

Background: Turraea vogelii has been used as traditional medicine for the treatment of ailments including wounds, stomach aches, malaria, infections, filariasis cutaneous, among others and, it serves as source of food. The present study aimed to evaluate the nutraceuticals content and topical anti-inflammatory effect of hydro-methanol twig extract of Turraea vogelii (METV). Method: METV was obtained using cold maceration with water and methanol in ratio 30:70. The concentration of vitamins A, C and E, total phenolic and total flavonoid contents were evaluated by UV spectrophotometric method. Phenol and xylene-induced ear edema was used to evaluate the topical anti-inflammatory effect in mice. Results: The concentration of vitamins A, C and E was found to be 0.113 0.006, 9.303 0.012 and 0.020 0.001 mg in 100g of dried plant materials, respectively. Total phenolic and flavonoid contents were 0.281 0.318 mg/g gallic acid equivalent and 0.112 mg/g quercetin equivalent, respectively. Topical application of METV at a dose of 25 and 50mg/ear in xylene-induced ear edema produced significant inhibition (P<0.05) of 33 and 54% while in phenol-induced ear edema was significantly (P< 0.05) reduced by 44% and 34%. Dexamethasone (0.1mg/ear) produced an inhibition of 83% and 57% in phenol-induced ear edema. Conclusion: Results from this study demonstrated that Turraea vogelii twigs contain flavonoids and phenolic compounds, which may be responsible for the topical anti-inflammatory effect of the plant extract.
The Protective Effect of Croton zambesicus against Carbon Tetrachloride-induced Renal Toxicity in Rats
Authors:   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin. Ilorin, Kwara State, Nigeria., Ayanniyi Rashidat Oluwafunke , Olumoh-Abdul Hidayah Ayodeji ,   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin. Ilorin, Kwara State, Nigeria., Ojuade Fatimoh Idowu ,   Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin. Ilorin, Kwara State, Nigeria., Abdullahi Rasheed ,   Department of Pharmacognosy and Drug Development, Faculty of Pharmaceutical Sciences, University of Ilorin. Ilorin, Kwara State, Nigeria., Anafi Sherifat Bola ,   Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Ahmadu Bello University. Zaria, Nigeria.
Published: June 2021

Background: The leaf extract of Croton zambesicus (CZ) is used in traditional medicine for the management of various conditions including kidney disease. The purpose of this study was to determine the protective effects of leaf extract of CZ on rat kidney toxicity induced by carbon tetrachloride. Method: Male albino rats were divided into 6 groups of 5 rats and treated for 5 days with aqueous extract (200-400 mg/kg) and n-butanol fraction (20-40 mg/kg) of CZ. Carbon tetrachloride (2 ml/kg of 40% in olive oil) was administered subcutaneously for 3 days and the rats were treated with the extract and fraction for 3 days. Animals were euthanized on day 8 with intraperitoneal injection of ketamine (60 mg/kg) and xylazine (7.5 mg/kg). Blood sample was collected for the analysis of serum electrolytes, urea and creatinine. Kidney tissue was harvested to determine the antioxidant enzyme activity. Results: Carbon tetrachloride produced increased serum sodium ion, chloride ion, urea and creatinine with decreased superoxide, catalase, glutathione, oxidized glutathione and an increase in malondialdehyde concentration. Treatment of rats with the aqueous leaf extract and n-butanol fraction attenuated the toxic effects of carbon tetrachloride on kidney with a significant decline in serum electrolytes, urea, creatinine and a significant increase in the concentration of antioxidant enzymes. Conclusion: Results from this study revealed that the aqueous leaf extract and n-butanol fraction of CZ had protective effect against carbon tetrachloride-induced renal toxicity in rats, thus justifying the consideration of this plant for the management of kidney disease.
Effects of Iron Oxide Nano-Particles on the Intestinal Tissue of Common Carp, Cyprinus Carpio
Authors:   epartment of Marine and Oceanic Sciences, University of Mazandaran. Babolsar, Iran., Omidzahir Shila , Alijantabar Bayi Maliheh ,   Department of Marine and Oceanic Sciences, University of Mazandaran. Babolsar, Iran., Kardel Fatemeh ,   Department of Environmental Sciences, University of Mazandaran. Babolsar, Iran., Mazandarani Mohammad ,   Department of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources. Gorgan, Iran.
Published: June 2021

Background: The application of nano-particles (NPs) in various industries is growing. Since their toxicity is not clearly understood, they can cause adverse effects on the environment. The aim of this study was to evaluate the histopathological effects of iron oxide nano-particles on the small intestine of common carp, Cyprinus carpio. Methods: Four experimental treatments were designed (15 fish/treatment). Treatment 1 was the controls while Treatments 2, 3 and 4 were experimental. The experimental groups were exposed to 50, 75 and the 100 mg/L of iron oxide NPs, respectively. On days 14, 21 and 28, the fish were randomly picked from each tank, samples of the small intestine were dissected, and were examined for both the accumulation of the iron NPs and the tissue histopathologies. Results: The highest concentration of iron accumulation was detected for Treatment 3 on day 21, compared to all other treatment groups (p<0.05). However, iron accumulation in the tissue declined unexpectedly after day 21 despite the continued treatments at 100 mg/L of the iron NPs. The histopathological examinations revealed that the treatment beyond 21 days caused damages to the intestinal epithelial cells, including enterocytes, villi and the goblet cells. Conclusion: This study demonstrated that the effect of iron oxide NPs on the small intestinal tissue was dependant on the dose and duration of exposure. We conclude that the iron accumulation in the small intestine declined despite increasing the iron oxide NPs concentration and the exposure duration secondary to damages caused to the intestinal epithelial cell layer.
Biochemical and Toxicological Studies of Bridelia micrantha [Berth] and Mitracarpus villosus [Swartz] DC Extracts used as Biofumigant Against Stored Produce Insect Pests on Albino Rats
Authors:   Department of Crop, Soil and Pest Management Technology, Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria., Adesina Jacobs Mobolade , Ofuya Thomas Inomisan ,   Department of Crop, Soil and Pest, Federal University of Technology, P. M. B. 704, Akure, Ondo State, Nigeria., Ileke Kayode David ,   Department of Biology, Federal University of Technology, P. M. B. 704, Akure, Ondo State, Nigeria., Rajashekar Yallappa ,   PhD of Biotechnology, Institute of Bioresources and Sustainable Development, Insect Ecology Laboratory, Takyelpat, Imphal, India., Mobolade-Adesina Titilayo Elizabeth ,   Department of Science Laboratory Technology, Rufus Giwa Polytechnic, Owo, Ondo State, Nigeria.
Published: June 2021

Background: In recent years, plant materials have been widely explored as sources of insect pest control agents with little or no study on their toxicity. The present study aimed to detect the biochemical alterations in liver and kidney associated with acute oral toxicity of the extracts of B. micrantha and M. villosus in albino rats. Methods: Twenty seven albino rats, weighing between 150-180g were used and divided into nine groups of three rats each, administered with different doses of each extracts (0, 500, 1000, 1500 and 2000mg/kg). The plasma and homogenates of liver and kidney of the rats were investigated for the activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALT), total protein, urea and creatinine, using standard laboratory kits. Results: The administration of either extract did not cause death or any hazardous symptoms of acute toxicity, nor resulted in any evident changes in the body weight. However, the extracts caused significant decreases in the levels of ALT, AST, ALP and total protein, urea and creatinine in biochemical parameters. They also caused a significant decrease in the serum parameters of treated rats’ liver and kidney at all doses. Conclusions: The results demonstrated that the oral administration of B. micrantha ethyl acetate extract and of M. villosus petroleum ether extract may be considered as moderately free of toxicity. This was based on our findings that two compounds were moderately safe with respects to their effects on the liver and kidney functions at concentrations of up to 2000 mg/kg body weight of the rats.
Microcystin-LR: Effects on Freshwater Catfish Heteropneustes fossilis Prolactin Cells
Authors:   Department of Zoology, DDU Gorakhpur University, Gorakhpur, India., Prakash Chandra , Srivastav Sunil Kumar ,   Department of Zoology, DDU Gorakhpur University, Gorakhpur, India.
Published: June 2021

Background: Previous studies have been reported on the toxicity of Microcystin-LR, which is produced by cyanobacterial growth in fish, such as Heteropneustes fossilis (H. fossilis). However, no studies have been conducted on the effects of Microcystin-LR on the prolactin cells of H. fossilis. Methods: H. fossilis fish were intraperitoneally injected with Microcystin-LR (2.5μg/25g) and sacrificed after 1, 3, 5, 10 and 15 days. The blood samples were analyzed for the calcium levels. Histological slides of the pituitary prolactin cells were stained with Herlant’s tetrachrome and Heidenhan’s azan techniques, and examined under light microscopy. Results: The prolactin cells exposed to Microcystin-LR exhibited no structural changes on day 1. However, hyperactive prolactin cells exhibited cellular degranulation from day 3 to day 5. On days 10 and 15, degenerated and vacuolated prolactin cells were also observed. The nuclear volume of prolactin cells exposed to MC-LR increased progressively from day 3 to day 10 but on day 15 the nuclear volume returned to normal. The serum calcium level of MC-LR injected specimens showed hypocalcemia from day 3 to day 10. On day 15, the level became normal. Conclusions: Our results indicated that the serum calcium levels and prolactin cells were altered after exposure to microcystin-LR.
Protective Effect of Flunixin meglumin on Changes Induced by Isoproterenol in Serum Biochemical Profile, Malondialdehyde and Heart Histology of Adult Male Rats
Authors:   DVM Student, Veterinary Medicine, Semnan University. Semnan, Iran., Tahery Shima , Ahmadi-Hamedani Mahmood ,   Department of Clinical Sciences, Faculty of Veterinary Medicine, Semnan University. Semnan, Iran., Keramati Keivan ,   Department of Basic Sciences, Faculty of Veterinary Medicine, Semnan University. Semnan, Iran., Javaheri Vayghan Abbas ,   Department of Pathobiology, Faculty of Veterinary Medicine, Semnan University. Semnan, Iran., Naeimi Saeideh ,   Department of Basic Sciences, Faculty of Veterinary Medicine, Semnan University. Semnan, Iran.
Published: June 2021

Background: Myocardial infarction (MI) is one of the most important causes of death worldwide. The effect of flunixin meglumine (FM) on MI is unknown. We investigated the protective effect of FM on the serum biochemical profile, malondialdehyde (MDA), and heart histology changes induced by isoproterenol (ISO) in adult male rats. Methods: Rats were randomly divided into four groups of six each as follows: Group 1, control. Group 2, was administered ISO subcutaneously at 85 mg/kg for 2 days. Group 3 was administered FM intraperitoneally at 2 mg/kg/d, for 3 days; and Group 4 was administered FM 2mg/kg/d intraperitoneally for 3 days and ISO 85mg/kg subcutaneously for two consecutive days. Blood samples were collected after anesthesia, 24h after the second ISO administration. The heart tissue was immediately removed for histopathological examination. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatine kinase (CK), lactate dehydrogenase (LDH), Blood urea nitrogen (BUN), creatinine and serum MDA levels were measured on an autoanalyzer and spectrophotometer. Results: In Group 4 (FM+ISO) the levels of AST, LDH and MDA decreased compared with those for Group 2 (ISO) (P< 0.05). Histopathologic tests revealed that ISO induced myocardial injury in Group 3 rats, whereas the alterations of the heart architecture were improved by FM in Group 4 (FM+ISO). Conclusions: The results suggest that FM has a potential cardioprotective effect against an experimental model of MI in rats.
A Tribute to Dr. Seyed Ali Fakhr Tabatabaei: A Legendary Neurosurgeon
Authors:   Department of Anesthesiology and Critical Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran., Hussain Khan Zahid , Zeinalizadeh Mehdi ,   Department of Neurological Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Published: June 2021

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Demographic Characteristics and Family History of Lumbar Problems in Patients with Lumbar Disc Degenerative Diseases Candidate for Surgery
Authors:   Deputy of Treatment, Guilan University of Medical Sciences, Rasht, Iran., Mashinchi Shiva , Yousefzadeh-Chabok Shahrokh ,   Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran., Dibavand Mesbah ,   Department of Neurosurgery, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Published: June 2021

Background and Aim: Previous studies have reported the important effect of age, sex, heredity, and occupational status on intervertebral degenerative dick diseases, which are among the most important causes of low back pain. However, their results are not always so conclusive. This study was performed to investigate the demographic characteristics and family history of lumbar problems in patients with lumbar degenerative dick diseases due to causes other than acute trauma. Methods and Materials/Patients: This cross-sectional descriptive study included patients without acute trauma who were candidates for surgery of lumbar degenerative dick diseases from 2017 to 2018 in the only state hospital admitting these patients in Rasht, Iran. The data related to the disease were obtained from the patients' medical records. Their demographic characteristics and family history of lumbar vertebrae diseases in their relatives were collected using a researcher-made questionnaire through face-to-face interview by the researcher. The data were analyzed using SPSS (Version 16). Descriptive statistics and the chi-square test were conducted at a significance level of 0.05. Results: More than half of the patients were in their 4th to 6th decades of life, and the number of men was 1.8 times as women. The frequency of herniated discs was more than that of both spinal canal stenosis and spondylolisthesis, and most people had no history of low back trauma. The duration of disease in 73% of the patients was more than 1 year and the mean duration was about 4.5 years. More than half of the patients reported problems with the lumbar vertebrae in at least 1 of their first-degree relatives. About one-third of the patients reported a history of vertebrae surgery in their first-degree relatives and the maximum number of reported surgeries in 1 family was 5. Most of the patients were low-literate and illiterate, and about one-third of the patients were workers/farmers. More than one-third of them were housewives and the number of patients working in administrative and driving jobs was very low. There was no significant relationship between study variables and the type of degenerative problems of the lumbar vertebrae. Conclusion: These findings showed similarities with previous studies in terms of age groups, occupational status, and a history of family lumbar problems in patients with lumbar degenerative disc diseases.
Intracranial Mass Lesion Due to Fungal Infection: A Case Series and Review of Literature
Authors:   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India., Gandhi Ashok , Jain Surendra ,   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India., Gandhi Sapna ,   Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India., Mishra Keshav ,   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India., Jain Sashikant ,   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India.
Published: June 2021

Background: Fungal infections of the central nervous system (CNS) usually present as subacute meningitis or intracranial space-occupying lesion with mass effect on surrounding structures and consequent focal neurological deficits. Intracranial fungal granulomas are often misdiagnosed clinically and radiologically as neoplastic lesions. Biopsy of the lesion is the only reliable technique to establish the correct diagnosis as well as to detect the causative fungal species. Voriconazole is a broad-spectrum triazole antifungal agent. It can be given orally and intravenously and has lesser adverse effects. Methods and Materials: In this article, we report a series of 6 cases of biopsy-proven fungal granuloma with varied clinical and radiological presentations who were given treatment with voriconazole for 6 months and demonstrated favorable response. Results: Out of 6 patients (4 males and 2 females), 1 was immunocompromised (DM with uncontrolled hyperglycemia). Headache was the most commonly observed symptom. Paranasal sinus and anterior cranial fossa were the most commonly affected site. Four patients received voriconazole therapy for 12 months and 1 received the same for 6 months before showing clinical resolution of disease. There was 1 death in the study group from non-related medical complications. Conclusion: Our series focuses on the correct diagnosis of fungal granuloma which can be achieved by biopsy and clinical evidence of the efficacy of voriconazole against intracranial fungal granuloma.
Role of Socio-demographic Factors in Predicting the Use of Communication Technologies by Older People in Iran
Authors:   Student Research Committee, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran., Habibollahpour Mitra , Motalebi Seyedeh Ameneh ,   Student Research Committee, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran., Mahdikhani Zahra ,   Student Research Committee, School of Nursing and Midwifery, Qazvin University of Medical Sciences, Qazvin, Iran., Mohammadi Fatemeh ,   Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran.
Published: June 2021

Background: The use of communication technologies enables the older people to deal with limitations and problems of modern life. Objective: This study aims to determine the socio-demographic factors predicting the use of common communication technologies (computers, internet, ATMs, and mobile phones) by the elderly in Iran. Methods: In this descriptive analytical study conducted in 2017, participants were 165 older adults from Qazvin, Iran who were selected using a cluster sampling method. Data collection tools were a demographic checklist and researcher-made questionnaire for assessing the use of communication technologies. Descriptive tests and multivariate regression analysis were used for data analysis. Findings: The mean age of participants was 68.38±7.89 years. Majority of them reported that they do not use computer (n=127, 77%) and internet services (n=112, 67.9%). The results of multivariate regression analysis showed that age (β=-0.209, P=0.002), gender (β=-0.142, P=0.029), educational level (β=0.501, P=0.000), and financial status (β=0.142, P=0.023) were the predictors of the use of common communication technologies by the older adults. Conclusion: A small percentage of the elderly in Iran use computer and internet. Therefore, it is very important to hold educational programs for the elderly to get familiar with and use new communication technologies.
Outcomes of Trauma and Their Relationship With Pre-hospital Time Intervals in Patients Admitted to a Hospital in Qazvin, Iran
Authors:   Department of Surgery, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran., Namdar Peyman , Norian Faranak ,   Student Research Committee, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran., Yazdi Zohreh ,   Department of Surgery, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran., Modirian Ehsan ,   Department of Surgery, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Published: June 2021

Background: Due to the importance of investigating the causes of trauma and functional indicators of pre-hospital emergency care. Objective: This study aims to evaluate the outcomes of trauma and their relationship with pre-hospital time intervals in patients admitted to Shahid Rajaei Hospital in Qazvin, Iran. Methods: In this descriptive study conducted in 2018, the medical records of 700 patients transported to Shahid Rajaei Hospital in Qazvin by Emergency Medical Services (EMS) ambulances were examined which were selected from 3200 cases using a systematic sampling method. We used a two-part questionnaire surveying demographic/clinical information of patients and their clinical outcomes. Findings: Mean age of patients was 33.8 years and 62% were male. Median of on-scene time, transport time, and total prehospital time were 7, 29.3 and 37 minutes, respectively. In overall, 72.4% of transferred patients were discharged from the emergency department, 19.7% admitted to other wards, and 4.4% discharged voluntarily. Conclusion: Time intervals of EMS in Qazvin city are suitable, and their provided pre-hospital services have acceptable quality.
Level of Academic Performance Among Faculty Members in the Context of Nepali Higher Educational Institution
Authors: Paudel Krishna Prasad
Published: June 2021

Academic performance is taken as the process of carrying out academic activities and discourses by faculty members to enhance their academic activities and discourses. The purpose of this research was to identify the faculty member's level of academic performance in higher educational institutions. To conduct this research, a quantitative methodology was employed. The tools to measure the academic performance of faculty members were developed using Delphi method. The data were collected with 445 sampled respondents from four universities. The factor analysis was used to explore the dimensions of academic performance. The factor analysis identified four factors of academic performance i.e., research and publication, innovation, interactive learning, and capacity building. To analyze the level of academic performance, mean and the standard deviation was used. It was found that individual differences and the organizational environment, culture, and technological infrastructure were crucial to influence the pace and level academic performance in academia.
Comparison of First-Year International Students' Adjustment to College at the Undergraduate and Graduate Level
Authors: Oyeniyi Odunola , Smith Robert L , Watson Joshua C , Nelson Kristina
Published: June 2021

Predictors of first-year undergraduate and graduate international students’ adjustment to college were examined using an online survey in 2019. The research sample consisted of 95 international students attending two universities in the United States. Findings showed a statistically significant difference between first-year graduate and undergraduate international students, as related to college adjustment. Further analysis discovered significant relationships among the predictor variables - resilience, relational skills, acculturative stress - and the criterion variable, which is adjustment to college, explaining 55% of the variance. Implications of findings for educators, college counselors, and college administrators, are provided, as well as directions for future research.
Selbstmordversuche in Macapá, Amapá, Amazonasgebiet, Brasilien, im Jahr 2018
Authors: Chagas Jéssica Andréa Silva das , Matos Talita de Oliveira , Dias Cláudio Alberto Gellis de Mattos , Dendasck Carla Viana , Oliveira Euzébio de , Araújo Maria Helena Mendonça de , Fecury Amanda Alves
Published: June 2021

Selbstmord ist der menschliche Akt, sein Leben zu beenden. Selbstmordeinstellungen mit der Absicht des Todes, aber ohne zum Tod zu führen, werden Selbstmordversuche genannt, dh sie sind absichtliche Handlungen der Selbstverletzung, ohne dass das Ergebnis der Tod ist. Diese Studie analysierte epidemiologisch die Versorgung des mobilen Rettungsdienstes – SAMU / AP im Zusammenhang mit Selbstmordversuchen im Jahr 2018 in Macapá / AP. Eine Querschnitts-, deskriptive und quantitative Untersuchung wurde durchgeführt. Die Daten wurden aus 61 Aufzeichnungen zur Erstversorgung, die sich auf Ereignisse im Jahr 2018 beziehen, aus dem SAMU / AP-Dateispeichersystem gesammelt. Diese Studie ermöglichte die Erweiterung des Wissens über die Merkmale der Fälle von Selbstmordversuchen und vollendeten Selbstmorden in Macapá / AP, wodurch die Unterstützung von Fachleuten ermöglicht wurde, an Interventionen mit der Bevölkerung zu arbeiten, um die vorhandenen Statistiken zu reduzieren. Es ist bemerkenswert, dass das Problem des Fehlens oder der Meldung von Fällen von Selbstmordversuchen, die nicht ausreichend durchgeführt wurden, ein wichtiger Aspekt für die Schwächung epidemiologischer Informationen, von Maßnahmen zur Netzwerkunterstützung und für die Verwirklichung von Territorialisierung und Intersektoralität bei der psychischen Gesundheit ist. Aufklärungsmaßnahmen und öffentliche Maßnahmen, die dem Arzt und den Erste-Hilfe-Teams im Allgemeinen die Bedeutung einer korrekten und vollständigen Registrierung von Informationen bestätigen.
Попытки самоубийства в Macapá, Amapá, регионе Amazônica, Бразилия, в 2018 г
Authors: Chagas Jéssica Andréa Silva das , Matos Talita de Oliveira , Dias Cláudio Alberto Gellis de Mattos , Dendasck Carla Viana , Oliveira Euzébio de , Araújo Maria Helena Mendonça de , Fecury Amanda Alves
Published: June 2021

Самоубийство – это человеческий акт прекращения жизни. Суицидальные отношения с намерением умереть, но не приводящие к смерти, называются попытками самоубийства, то есть они являются преднамеренными актами самоповреждения, результатом которых не является смерть. В этом исследовании с эпидемиологической точки зрения была проанализирована помощь, оказываемая Мобильной службой экстренной помощи – SAMU / AP в связи с попытками самоубийства в 2018 году в Macapá/AP. Было проведено поперечное, описательное и количественное исследование. Данные были собраны из 61 первичной медицинской карты, относящейся к событиям в 2018 году, из файловой системы хранения SAMU / AP. Это исследование позволило расширить знания о характеристиках случаев попыток самоубийства и завершившихся самоубийств, имевших место в Macapá/AP, что позволило профессионалам работать с населением в целях сокращения существующей статистики. Примечательно, что проблема отсутствия или уведомления о случаях попытки самоубийства, выполненной в недостаточной степени, является важным аспектом для ослабления эпидемиологической информации, сетевых действий по оказанию помощи и для реализации территориализации и межсекторальности в области психического здоровья. Образовательные мероприятия и общественная политика, которые разъясняют врачам и бригадам первой помощи в целом важность правильной и полной регистрации информации.
Intentos de suicidio en Macapá, Amapá, Región Amazónica, Brasil, en 2018
Authors: Chagas Jéssica Andréa Silva das , Matos Talita de Oliveira , Dias Cláudio Alberto Gellis de Mattos , Dendasck Carla Viana , Oliveira Euzébio de , Araújo Maria Helena Mendonça de , Fecury Amanda Alves
Published: June 2021

El suicidio es el acto humano de acabar con la vida. Las actitudes suicidas con intención de muerte, pero sin llevar a la muerte, se denominan intentos de suicidio, es decir, son actos intencionales de autolesión sin que el resultado sea la muerte. Este estudio analizó epidemiológicamente la atención brindada por el Servicio Móvil de Emergencias – SAMU / AP relacionada con intentos de suicidio en 2018 en Macapá / AP. Se realizó una investigación transversal, descriptiva y cuantitativa. Se recolectaron datos de 61 registros de atención inicial referentes a las ocurrencias realizadas en 2018, del sistema de almacenamiento de archivos SAMU / AP. Este estudio permitió ampliar el conocimiento de las características de los casos de suicidio e intentos de suicidio ocurridos en Macapá / AP, posibilitando así el apoyo de los profesionales para trabajar en intervenciones con la población en busca de la reducción de las estadísticas existentes. Es de destacar que el problema de la falta o notificación de casos de intento de suicidio realizados de manera insuficiente es un aspecto importante para el debilitamiento de la información epidemiológica, de las acciones de asistencia en red y para la realización de la territorialización e intersectorialidad en salud mental. Acciones educativas y políticas públicas que refuercen al médico y a los equipos de primeros auxilios en general la importancia del registro correcto y completo de la información.
Tentatives de suicide à Macapá, Amapá, région amazonienne, Brésil, en 2018
Authors: Chagas Jéssica Andréa Silva das , Matos Talita de Oliveira , Dias Cláudio Alberto Gellis de Mattos , Dendasck Carla Viana , Oliveira Euzébio de , Araújo Maria Helena Mendonça de , Fecury Amanda Alves
Published: June 2021

Le suicide est l’acte humain de mettre fin à sa vie. Les attitudes suicidaires avec l’intention de mourir, mais sans conduire à la mort, sont appelées tentatives de suicide, c’est-à-dire qu’il s’agit d’actes d’automutilation intentionnels sans que le résultat en soit la mort. Cette étude a analysé, épidémiologiquement, les soins fournis par le Mobile Emergency Service – SAMU / AP liés aux tentatives de suicide en 2018 à Macapá / AP. Une recherche transversale, descriptive et quantitative a été menée. Les données ont été collectées à partir de 61 enregistrements de soins initiaux faisant référence aux événements survenus en 2018, à partir du système de stockage de fichiers SAMU / AP. Cette étude a permis d’élargir la connaissance des caractéristiques des cas de suicide et de tentatives de suicide survenus à Macapá / AP, permettant ainsi au soutien de professionnels de travailler sur des interventions auprès de la population à la recherche de la réduction des statistiques existantes. Il est à noter que le problème de l’absence ou de la notification des cas de tentative de suicide exécutés de manière insuffisante est un aspect important pour l’affaiblissement de l’information épidémiologique, des actions d’assistance en réseau et pour la réalisation de la territorialisation et de l’intersectorialité en santé mentale. Actions éducatives et politiques publiques qui renforcent auprès du médecin et des équipes de premiers secours en général l’importance d’un enregistrement correct et complet des informations.
DIGITAL GLOBALIZATION IN THE ERA OF THE FOURTH INDUSTRIAL REVOLUTION: POTENTIAL FOR TRANSFORMATION
Authors:   V. N. Karazin Kharkiv National University, Dovgal Olena , Dovgal Georgiy ,   V. N. Karazin Kharkiv National University
Published: June 2021

The article considers the potential for transformation of the world economy under the influence of digital globalization in the era of the fourth industrial revolution. It is substantiated that within the framework of digital globalization the paradigm of organization of production, configuration and content of international trade are changing. At the same time, the process of digitalization leads to qualitative changes in all spheres of production, economic and trade activities around the world. Formation of production technological processes using the Internet of Things, modules of artificial intelligence and 3D-printing allows to reduce production costs and increase the competitiveness of products. Attention is focused on the essence of the changes taking place, the directions of the vectors of economic development in the context of the changing digital space. Particular attention is paid to the functioning of new business models (in particular, digital platforms), the transformation of the structure, configuration, forms and methods of international trade, as well as the impact of ongoing processes on international competitiveness. An important place is given to the problems of e-commerce, the content of the processes taking place in this segment of international economic relations. Some approaches to solving the problems of digitalization at the international and national levels are proposed. In the global dimension, it is important to ensure, through the adoption of binding legal documents for WTO member states on the freedom of information exchange, aimed at stimulating innovative development, promoting the removal of barriers in the e-commerce segment, encouraging investment in digital infrastructure and human capital. . The development of the country's digital potential and digital infrastructure involves the implementation of localization measures, ie requires the creation of national platforms for the accumulation and storage of information. It is concluded that the global process of digitalization creates the potential for dynamic development of new business models, stimulates productivity and increases competitiveness.
Madrasah Promotion Strategies in the Global Work Market 4.0
Authors: Sukarman Sukarman , Raharjo Raharjo
Published: June 2021

Students are an important element in education. Successful educational institutions are those who are successful in student recruitment. Educational institutions that are successful in student recruitment are institutions that have succeeded in gaining trust from the community. Madrasah Aliyah Matholiul Huda Jepara as one of the Islamic-style educational institutions has its own challenges in recruiting students. This madrasa is a madrasa that successfully competes with schools and other madrassas in gaining trust from the community which is marked by the success of the student recruitment program. This research attempts to reveal the strategies adopted by Madrasah Aliyah Matholiul Huda Jepara in promoting their institutions. This research is a case study research that uses a qualitative descriptive approach. This study uses interviews, observation, and documentation in collecting data. data reduction, data display, data verification and triangulation are used for data validity analysis. The findings of this study are divided into two aspects namely the method and media of promotion used. First, Madrasah Aliyah Matholiul Huda applies direct and indirect promotion methods. Second, Madrasah Aliyah Matholiul Huda uses conventional and digital (online) promotional media. This paper provides an alternative solution for madrassas who have backgrounds or problems in the recruitment of students, especially promotion strategies. The conclusion of this paper is that to be successful in recruiting students, madrassas must choose the appropriate method and media in promoting madrassas by paying attention to the SWOT analysis.

Keywords : madrasa promotion,  students recruitment
STRENGTHENING THE TRADITIONAL DANCE GROUP & PLACE (SANGGAR TARI) TO STRENGTHEN THE LOCAL CULTURE OF MEDAN IN MEDAN AMPLAS SUBDISTRICT
Authors: Agustono Budi , Dewi Heristina , Pujiono Mhd.
Published: June 2021

The majority of the younger generation ignore national culture, such as traditional dances, and prefer modern dances. This makes the importance of strengthening traditional dance groups & place (sanggar tari) as a forum for developing creativity in traditional culture in Medan. Therefore, in this community service, efforts to strengthen the sanggar tari to strengthen Medan's local culture were carried out. This activity consisted of a Focus Group Discussion (FGD) and dance training for 30 young men and women members of the Medan Amplas sub-district sanggar tari held for two months. Besides providing training, the community service team facilitates supporting equipment in traditional dance performance activities for members, such as clothing, accessories, and other training media. The lecture, Q&A, demonstration, and drill methods are used in its implementation. This community service has resulted in the form of services to raise public awareness of the local dance culture of North Sumatera, especially in Medan, with training assistance to increase creativity, innovation, and the ability of the sanggar members in the field of traditional dance and culture.