bluuebunny/crossref_metadata_2025 huggingface dataset:
Sites and Time of Oviposition of Euphyllura phillyreae Foerster on Olive Trees and οon Phillyrea latifolia
Authors: Prophretou-Athanasiadou D.A. , Tzanakakis M.E
Published: November 2017

The distribution of eggs of Euphyllura phillyreae Foerster (Homoptera: Aphalaridae) was recorded on twigs of olive trees and of Phillyrea latifolia L. in various locations of the Thessaloniki and Halkidiki prefectures of coastal northern Greece. On olive, the first eggs were observed in the last ten days of March and oviposition was intensified and became abundant only when the apical bud and the axillary leaf and flower buds started to swell. Eggs were laid mostly on swollen buds and on developing inflorescences. Oviposition preference was related to the stage of development of a bud and not to its location on the olive twig. On swollen leaf buds, most eggs were laid on the inner (upper) surface of the middle (second) pair of developing leaves, and fewer on the inner surface of the outer (first) pair and on the innermost (third) pair of leaves. On Phillyrea, eggs were deposited much earlier than on olive, on developing inflorescences. In choice and no-choice laboratory experiments, more eggs were laid on olive twigs bearing developing inflorescences, fewer eggs on twigs bearing only swollen terminal or axillary buds, and no eggs at all on twigs with only fully developed leaves of the previous year.
Effect of SSP – 11 on Weight and Tissue Composition of 4th Instar Larvae of Silkworm, Bombyx mori
Authors: Υenkata Rami Reddy K. , Sashindran Nair K. , Magadum S. Β. , Datta R. Κ.
Published: November 2017

The anti-juvenoid, SSP-11 ((E) 4-chloro-a, a, a-trifluro-N [ 1 (1 H-imidazole- 1 –y1)- 2-propoxy ethylyledene] O, toludine) was used to induce trimoulters from tetramoulter larvae of the silkworm, Bombyx mori (race NB7). The compound was fed for two days through an artificial diet at the concentration of 200 ppm to newly ecdysed 4th stadium larvae. Body and silkgland fresh weight were recorded daily in the 4th larval stadium and protein profiles of haemolymph, fat body and silkgland were determined at the end of the stadium. In larvae treated with SSP-11, feeding period in stadium 4 was prolonged by 3-4 days and 80-85% of the larvae started to spin as trimoulters. Eight and thirty fold increases in the larval body and silkgland weights respectively were the result of SSP-11. Further, total proteins, total carbohydrates, glycogen and nucleic acid (DNA & RNA) also increased. The activity levels of alanine aminotransferase and aspartate aminotransferasc increased significantly than in the control indicating increased mobilization of aminoacids into transamination activities.
Check list of the Dryopidae, Elmidae and Hydraenidae (Coleoptera) of Greece
Authors: Jach Μ. Α. , Avtzis Ν. D.
Published: November 2017

Information on the Greek water beetle families Dryopidae, Elmidae and Hydracnidae is fairly scattered throughout the literature. Our knowledge of these families which inhabit mainly running water largely results from numerous short excursions, collecting trips and limnological projects carried out by numerous European entomologists (e.g. P. Audisio, G. Ferro, M.A. Bch, E. Janssens, H. Malicky, A. d’Orchymont, F. Wachtel). However, a concise summary of the Dryopidae, Elmidae and Hydraenidae known from Greece has never been published. This survey is mainly based on literature records. However, a number of species which were recently collected in Greece are recorded for the first time from that country. In the following check list, the names of the species (or subspecies) are followed by the name(s) of the authors) and by one important reference which contains information about the species distribution in Greece. Ten species are herein recorded from Greece for the first time.
The Use of Chemicals with Specific Mode of Action in an Integrated Control Program on Eggplant for the Greenhouse Whitefly, Triαleurodes vαporαriorum
Authors: Abdalla Safel Dawla , Michelakis S.
Published: November 2017

In the unheated plastic greenhouses of Crete, the control of the greenhouse whitefly Trialeurodes vaporariorum Westwood using chemicals is usually needed during winter time. The systemic insecticide Vydate when applied as soil granules at the highest dose (2g/plant), gave protection for young eggplants against whitefly for a period of 5 weeks. Experiment with different chemicals showed that the new insect growth regulator Nomolt, is fairly effective in controlling the greenhouse whitefly when used in combination with Actellic. It gave equally good results when compared with a mixture of Applaud and Actellic.
The effect of C6- to CIO- fatty acids on larval growth and survival of the olive fruit fly Bactrocera oleae (Diptera: Tephritidae)
Authors: Manoukas A. G.
Published: November 2017

The effects of caproic (C6), amino caproic (C6), caprylic (C8) and cupric (CIO) acid on larval performance of the olive fruit fly, Bactrocera oleae (Gmelin) (Diptera: Tephritidae) were investigated. The acids were added to an artificial larval diet at four different concentration levels, during the mixing of its ingredients. Eggs obtained from a colony of olive fruit flies were placed on these diets and on the control. caproic acid depressed significantly egg hatchability, larval survival and larval weight at the dietary level of 0.05 and 0.1 %. In addition, it did not permit eggs to hatch at the level of 0.2%. On the contrary, aminocaproic acid did not depress any of the parameters recorded up to the level of 0.2%. The levels of 0.4 to 1.6% depressed larval survival larval growth and pupal weight and the level of 3.2% did not permit larvae to survive. caprylic acid depressed significantly hatchability, larval survival and number of pupae/g diet at the level of 0.0125% and gave no pupae at the level of 0.1%. Finally cupric acid depressed egg hatchability, larval survival and larval weight from the level of 0.05% and gave no pupae at the level of 0.2%, Adult emergence was not affected by any of the acids tested.
Entomopathogens of Anαcridium αegyptium L. in Crete
Authors: Roditakis Ν. Ε. , Kollaros D. , Legakis Α.
Published: November 2017

The entomopathogenic fungus Beauveria bassiana (Bals.) Vuil. was recorded for the first time on Anacridium aegyptium L. in Crete. The insects were fed on pieces of leaf subjected to a serial dilution of spores over three to four orders of magnitute. Comparative studies on the virulence of B. bassiana (I 91612 local isolate) and Metarhizium anisopliae var. acridum (IMI 330189 standard isolate of IIBC) showed that M. anisopliae var. acridum was more virulent than B. bassiana at a conidial concentration lower or equal to 106 per ml while they were similarly virulent on first stage nymphs at 107 conidia per ml.
The decision to delivery interval in emergency caesarean sections: Impact of anaesthetic technique and work shift
Authors: Hein Anette , Thalen David , Eriksson Ylva , Jakobsson Jan G.
Published: November 2017

Background: One important task of the emergency anaesthesia service is to provide rapid, safe and effective anaesthesia for emergency caesarean sections (ECS). A Decision to Delivery Interval (DDI) <30 minutes for ECS is a quality indicator for this service. The aim of this study was to assess the DDI and the impact of chosen anaesthetic technique (general anaesthesia (GA), spinal anaesthesia (SPA) with opioid supplementation, or “top-up” of labour epidural analgesia (tEDA) with local anaesthesia and fentanyl mixture) and work shift for ECS at Danderyds Hospital, Sweden.

Methods: A retrospective chart review of ECS at Danderyds Hospital was performed between January and October 2016. Time between decision for CS, start of anaesthesia, time for incision and delivery, type of anaesthetic technique, and time of day, working hours or on call and day of week, Monday – Friday, and weekend was compiled and analysed. Time events are presented as mean ± standard deviation. Non-parametric tests were used.

Results: In total, 135 ECS were analysed: 92% of the cases were delivered within 30 minutes and mean DDI for all cases was 17.3±8.1 minutes. GA shortened the DDI by 10 and 13 minutes compared to SPA and tEDA (p<0.0005). DDI for SPA and tEDA did not differ. There was no difference in DDI regarding time of day or weekday. Apgar <7 at 5’ was more commonly seen in ECS having GA (11 out of 64) compared to SPA (2/30) and tEDA (1/41) (p<0.05).

Conclusion: GA shortens the DDI for ECS, but the use of SPA as well as tEDA with opioid supplementation maintains a short DDI and should be considered when time allows. Top-up epidural did not prolong the DDI compared to SPA. The day of week or time of ECS had no influence on the anaesthesia service as measured by the DDI.
Administrative procedure law
Authors: Миронов Анатолий , Mironov Anatoliy
Published: November 2017

Administrative procedure law represents one of the fastest growing industries of the Russian right. The guide discusses the main categories of administrative-procedural law: concept, principles, stage of the administrative process, administrative proceedings. Special attention is paid to the coverage of certain types of administrative proceedings: proceedings for the adoption of regulatory acts, licensing the manufacture, registration, production Supervisory production, production on Affairs about the promotion, manufacture on Affairs about administrative offences, disciplinary proceedings etc.
Rising Prices Under Declining Preferences: The Case of the U.S. Print Newspaper Industry
Authors: Pattabhiramaiah Adithya , Sriram S. , Sridhar Shrihari
Published: November 2017

Between 2006 and 2011, daily print newspapers in the United States lost 20% of their paid subscribers, partly because of the increasing availability of alternative sources of news, such as free content provided on newspaper websites and by news aggregators such as Yahoo. However, contrary to the expectation that firms respond to softening demand by lowering prices, newspapers increased subscription prices by 40%–60% during this period. In this paper, we explain and quantify the factors responsible for these price increases. We calibrate models of readership and advertising demand using data from a top-50 U.S. regional print newspaper. Conditional on these demand models, we calibrate the newspaper’s optimal pricing equations and assess whether the increases in subscription prices are mainly rationalized by (a) the decline in overall reader willingness to pay (WTP) in the presence of heterogeneity among subscribers, which rendered it optimal for the newspaper to focus on the high WTP readers, or (b) the newspaper’s reduced incentive to subsidize readers at the expense of advertisers, because of softening demand for newspaper advertising. We find that the decline in the ability of the newspaper to subsidize readers by extracting surplus from advertisers explains most of the increase in subscription prices. Of the three available subscription options (daily, weekend, and Sunday only), subscription prices increased more steeply for the daily option, a pattern consistent with the view that newspapers are driving away low valuation weekday readers while preserving Sunday readership and the corresponding ad revenues. Thus, our research augments theoretical propositions in two-sided markets by providing a formal empirical approach to unraveling the relative importance of the roles played by agents on the subsidy and demand sides in determining prices.

Data and the online appendix are available at https://doi.org/10.1287/mksc.2017.1060 .
Perceptions of ‘physical activity’ and ‘exercise’ among people living with HIV: A qualitative study
Authors: Vader Kyle , Simonik Alya , Ellis Denine , Kesbian Dirouhi , Leung Priscilla , Jachyra Patrick , Carusone Soo Chan , O'Brien Kelly K
Published: November 2017

Background/Aims:

Many people living with HIV do not engage in regular physical activity and it is unclear how perceptions of physical activity and exercise influence participation. Our aim was to explore individual perceptions of physical activity and exercise in people living with HIV.

Methods:

We conducted a descriptive qualitative study using face-to-face semi-structured interviews. We recruited adults who self-identified as living with HIV from a speciality hospital in Toronto, Canada. Interviews were audio-recorded, transcribed verbatim, and analysed using thematic analysis.

Findings:

A total of 14 participants with a median age of 50 years participated in the study. Four themes (and subsequent sub-themes) emerged relating to physical activity and exercise. These included: (1) perceptions of physical activity and exercise (seeing them as a continuum of activity, as a health-promoting behaviour, and that they ‘should’ be a greater priority); (2) benefits (restores physical function, improves mental health, and prevents isolation); (3) risks (physical injury, pain, and fear of ‘overdoing it’); and (4) recommendations for engagement (education, graded activity, and an individualised approach).

Conclusions:

Findings suggest health care professionals should consider exploring perceptions of physical activity and exercise among people living with HIV to ensure physical activity interventions are individualised to meet their diverse health and wellbeing needs.
Who Helps? Characteristics and Correlates of Informal Supporters to Adults With Disabilities
Authors: Sanderson Kelli A. , Burke Meghan M. , Urbano Richard C. , Arnold Catherine K. , Hodapp Robert M.
Published: November 2017

This study examined who provides informal (or unpaid) supports to people with intellectual and developmental disabilities (IDD). Participants included 657 adult siblings of people with disabilities who responded to a national survey about informal supports in the areas of recreation, employment, and housing. Results indicated that most people with IDD received informal supports, with parents and sibling respondents most often providing those supports. Support was most commonly received in recreation, as opposed to housing or employment. Asked to list nonfamily informal supporters, respondents often mentioned paid staff and disability organizations. Correlates of total numbers of informal supporters included the individual with disability's functioning level and parents' ability to care for their offspring with disabilities.
The Feasibility of Group Video Conferencing for Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities
Authors: Ptomey Lauren T. , Willis Erik A. , Greene J. Leon , Danon Jessica C. , Chumley Tara K. , Washburn Richard A. , Donnelly Joseph E.
Published: November 2017

Physical activity (PA) rates of adolescents with intellectual and developmental disabilities (IDD) are low and effective strategies for increasing PA are limited. The purpose of this study was to assess the feasibility of a group-based PA intervention that was delivered remotely to adolescents with IDD. Participants attended 30-min group PA sessions 3 times a week. PA sessions were delivered in their homes by video conferencing on a tablet computer. Thirty-one participants enrolled and 29 completed the 12-week intervention. Participants attended 77.2% ± 20.8% of scheduled sessions and averaged 26.7 ± 2.8 min of PA/session, with 11.8 ± 4.8 min at moderate- to vigorous intensity. Group-based PA delivered remotely may be a feasible approach for the promotion of PA in adolescents with IDD.
Leukocyte Counts Based on DNA Methylation at Individual Cytosines
Authors: Frobel Joana , Božić Tanja , Lenz Michael , Uciechowski Peter , Han Yang , Herwartz Reinhild , Strathmann Klaus , Isfort Susanne , Panse Jens , Esser André , Birkhofer Carina , Gerstenmaier Uwe , Kraus Thomas , Rink Lothar , Koschmieder Steffen , Wagner Wolfgang
Published: November 2017

BACKGROUND

White blood cell counts are routinely measured with automated hematology analyzers, by flow cytometry, or by manual counting. Here, we introduce an alternative approach based on DNA methylation (DNAm) at individual CG dinucleotides (CpGs).

METHODS

We identified candidate CpGs that were nonmethylated in specific leukocyte subsets. DNAm levels (ranging from 0% to 100%) were analyzed by pyrosequencing and implemented into deconvolution algorithms to determine the relative composition of leukocytes. For absolute quantification of cell numbers, samples were supplemented with a nonmethylated reference DNA.

RESULTS

Conventional blood counts correlated with DNAm at individual CpGs for granulocytes (r = −0.91), lymphocytes (r = −0.91), monocytes (r = −0.74), natural killer (NK) cells (r = −0.30), T cells (r = −0.73), CD4+ T cells (r = −0.41), CD8+ T cells (r = −0.88), and B cells (r = −0.66). Combination of these DNAm measurements into the “Epi-Blood-Count” provided similar precision as conventional methods in various independent validation sets. The method was also applicable to blood samples that were stored at 4 °C for 7 days or at −20 °C for 3 months. Furthermore, absolute cell numbers could be determined in frozen blood samples upon addition of a reference DNA, and the results correlated with measurements of automated analyzers in fresh aliquots (r = 0.84).

CONCLUSIONS

White blood cell counts can be reliably determined by site-specific DNAm analysis. This approach is applicable to very small blood volumes and frozen samples, and it allows for more standardized and cost-effective analysis in clinical application.
Produção, correção e reescrita textual: resultados de uma pesquisa-ação-crítico-colaborativa
Authors: Turkiewicz Rosemary De Oliveira Schoffen , Costa-Hübes Terezinha Da Conceição
Published: November 2017

Neste artigo, nosso propósito é de divulgar alguns resultados decorrentes da participação de professoras do ensino fundamental em uma pesquisa-ação-crítico-colaborativa que realizamos no município de Goioerê-PR. Por meio da pesquisa, objetivamos provocar reflexões sobre o ensino da produção escrita na escola, abrangendo o encaminhamento da produção textual, da revisão/correção e da reescrita de textos, na perspectiva de colaborar com a prática docente, de modo a torná-la mais consistente e consoante com a concepção dialógica e interacionista de linguagem, conforme os pressupostos teóricos e metodológicos que regem os atuais referenciais curriculares de Língua Portuguesa. Dados os limites deste texto, nos propomos a analisar um recorte dos dados gerados no contexto da pesquisa, focalizando alguns encaminhamentos docentes de uma das professoras colaboradoras para a produção, correção e reescrita de textos, em aulas ministradas em turmas do ensino fundamental, antes e após as ações colaborativas. Para proceder a esta análise, sustentamo-nos em pressupostos teóricos do Círculo de Bakhtin, nos estudos de Vygotsky (1991), na proposta de Geraldi (2006[1984]), Magalhães (2004), Ruiz (2010), Menegassi (2010,2012), Costa-Hübes (2012), entre outros. Como resultado, destacamos a importância de desenvolvermos uma pesquisa-ação-crítico-colaborativa, tendo em vista as contribuições dessa colaboração com a prática docente.Palavras-chave: Pesquisa-ação-crítico-colaborativa. Formação continuada de professores. Produção textual. Reescrita textual.
The meaning and madness of money: A Semio-ecological analysis
Authors: Brandt Per Aage
Published: November 2017

In this paper, I propose an overall model of the semantic and semiotic functions of money and capital forms based on an ecological view of human activity and a theory of the origin of money (coined precious metals). The
Debtors, creditors, and sovereign money: A case for institutional blending and the amalgamated mind
Authors: Oakley Todd
Published: November 2017

Much social cognition and action is dialogical in nature and profitably understood from a second-person perspective. The elemental social roles of “debtor” and “creditor” are of great importance in explaining the structure and history of a wide range of social facts and institutions. Yet these person-level experiences of indebtedness and the mental spaces they engender are not sufficient to account for complex social facts. Sovereign money systems are a leading example where our person-level experiences of exchange lead us astray by actively hindering our ability to grasp money’s macroeconomic functions. This article provides a comprehensive account of money as a distributed cognitive phenomenon. It summarizes and critiques a prior analysis of money as a conceptual blend enabling
Poly(N-isopropylacrylamide)-coated gold nanorods mediated by thiolated chitosan layer: thermo-pH responsiveness and optical properties
Authors: Esquivel Reynaldo , Canale Iván , Ramirez Maricela , Hernández Pedro , Zavala-Rivera Paul , Álvarez-Ramos Enrique , Lucero-Acuña Armando
Published: November 2017

A core-shell of colloidal metal-responsive polymer provides an innovative model in functional materials. These core-shell nanocomposites offer the possibility to control some properties, such as particle size, surface plasmon resonance and morphology. In this research, we demonstrate the successful synthesis and functionality of gold nanorods (GNR) coated with the polymers chitosan (Ch) and poly(N-isopropylacrylamide) (PNIPAM). The polymer coatings are performed using a two-step method. First, GNR were coated with a thiolated chitosan (GNR-Ch) by replacing hexadecyltrimethylammonium bromide with a chitosan thiomer. Structural modification of GNR-Ch was monitored by Fourier transform infrared spectroscopy. Then a second polymeric coating was done by in situ free radical polymerization of N-isopropylacrylamide (NIPAM) on GNR-Ch to obtain the nanocomposite GNR-Ch-PNIPAM. The nanocomposite average size was analyzed by dynamic light scattering. The evolution of ζ potentials during the coatings was measured using electrophoretic mobility. GNR-Ch-PNIPAM presented a collapsed structure when heated above the lower critical solution temperature. The particle size of GNR-Ch-PNIPAM was manipulated by changing the pH. Plasmonic properties were evaluated by UV-Vis spectroscopy. Results showed an important blue shift due to the PNIPAM coating thickness. Thermo- and pH-responsive properties of the nanocomposite GNR-Ch-PNIPAM could be used as a drug delivery system.
One-pot synthesis of benzopyrans catalyzed by silica supported dual acidic ionic liquid under solvent-free conditions
Authors: Zhang Qiang , Wei Huaixin , Li Jihang , Zhao Xin , Luo Jun
Published: November 2017

A mild and efficient method was developed for the preparation of tetrahydrobenzo[b]pyrans through a one-pot three-component condensation of aldehydes, malononitrile and dimedone in the presence of silica supported dual acidic ionic liquid (DAIL@SiO2) as a powerful catalyst under solvent-free conditions. This procedure is characterized by mild reaction conditions, simple workup and environmental friendliness. Moreover, the catalyst could be recycled for five times with only a slight loss of catalytic activity.
Enterobiasis epidemiology and molecular characterization of Enterobius vermicularis in healthy children in north-eastern Poland
Authors: Kubiak K. , Dzika E. , Paukszto Ł.
Published: November 2017

Enterobiasis is a human intestinal parasitic disease caused by human pinworm, Enterobius vermicularis. Despite being the most prevalent nematode infection in Europe and North America, predominantly among in school aged children, the data concerning infection rate and knowledge of genetic variability of pinworms are incomplete. The aim of the study was the estimation of prevalence and molecular typing of Enterobius vermicularis among healthy children in north-eastern Poland. In 2013 – 2015, 296 individuals (aged 2 – 18 years) from 12 kindergartens, schools and orphanages were examined by the adhesive cellophane tape method. Data on socio-demographic status were collected using a questionnaire. Molecular analysis was performed using the DNA of adult female pinworms and primers targeting the region of cytochrome oxidase I gene. The overall prevalence of enterobiasis was 10.1 %. Enterobius vermicularis infection rates were 3.9 % in children living in families and 32.8 % among the orphans (OR=0.08; 95 % CI: 0.04 – 0.19; p<0.001). There were no associations between distribution of enterobiasis and gender, pets possession and the season of examination. In 43.3 % of the infected children enterobiasis was asymptomatic. Based on a molecular marker three different haplotypes of pinworm were identified. All sequences clustered within type B, together with human E. vermicularis isolates from Denmark, Germany, Greece, and Japan. This paper provides complementary data on the occurrence and intraspecific variability of E. vermicularis in human population in Europe.
Endoscopic treatment of early colorectal cancer – just a competition with surgery?
Authors: Ebigbo Alanna , Probst Andreas , Messmann Helmut
Published: November 2017

The endoscopic treatment of cancerous and precancerous lesions in the gastrointestinal (GI) tract has experienced major breakthroughs in the past years. Endoscopic mucosal resection (EMR) is a simple and efficient method for the treatment of most benign lesions in the GI tract. However, with the introduction of endoscopic submucosal dissection (ESD) and endoscopic full-thickness resection (EFTR), the scope of lesions eligible for endoscopic treatment has been widened significantly even in the colon. These methods are now being used routinely not just for the treatment of benign lesions but also in the curative en bloc resection of early colorectal cancers. The quick, efficient, and noninvasive character of these endoscopic procedures make them not just an alternative to surgery but, in many cases, the methods of choice for the treatment of most early colon cancers and some rectal cancers.
First-line antituberculosis drugs disrupt endocrine balance and induce ovarian and uterine oxidative stress in rats
Authors: Adebayo Olayinka A. , Adesanoye Omolola A. , Abolaji Olalekan A. , Kehinde Aderemi O. , Adaramoye Oluwatosin A.
Published: November 2017

Background:

The first-line antituberculosis (anti-TB) drugs, isoniazid (INH), rifampicin (RIF), ethambutol (EMB), and pyrazinamide (PZA), are effective in the treatment of pulmonary tuberculosis. However, the toxicity of these drugs in the clinical setting limits their use. Here, we evaluated the effects of anti-TB drugs on the reproductive system in female rats.

Methods:

Thirty-five female Wistar rats were assigned into five groups of seven animals each. The control group received normal saline, whereas others received INH (5 mg/kg), RIF (10 mg/kg), EMB (15 mg/kg), and PZA (15 mg/kg) through gavage thrice a week for 8 consecutive weeks.

Results:

Administration of anti-TB drugs significantly (p<0.05) reduced uterine and ovarian weight, as well as the relative weight of the uterus when compared with controls. In addition, anti-TB drugs increased the activities of alanine aminotransferase as well as the level of total bilirubin. Treatment with INH, RIF, and PZA significantly (p<0.05) reduced the levels of follicle-stimulating and luteinizing hormones, estrogen, and prolactin. The INH, RIF, EMB, and PZA caused significant (p<0.05) increases in uterine malondialdehyde (MDA) levels by 281%, 214%, 273% and 190%, respectively, whereas INH and EMB increased the ovarian malondialdehyde by 111% and 129%, respectively. These drugs significantly (p<0.05) decreased the activities of ovarian glutathione-S-transferase and uterine glutathione peroxidase, superoxide dismutase, and catalase. Histology revealed the erosion of uterine mucosa, debris in the lumen of the uterus, congestion, and underdeveloped follicles in ovaries.

Conclusions:

The first-line anti-TB drugs elicited reproductive toxicity in the uterus and ovaries of rats through mechanisms that involved oxidative stress.
The Limits of the Goat Song in Edward Albee’s The Goat or Who is Sylvia?
Authors: Wagoner Michael M.
Published: November 2017

Both critical discussion and performance reviews of Edward Albee’s
On groups with formational subnormal Sylow subgroups
Authors: Monakhov Victor S. , Sokhor Irina L.
Published: November 2017

We investigate a finite group G with

𝔉

{\mathfrak{F}}

-subnormal Sylow subgroups,
where

𝔉

{\mathfrak{F}}

is a subgroup-closed formation and

𝔄
1

⁢
𝔄

⊆
𝔉
⊆

𝔑
⁢
𝒜

{\mathfrak{A}_{1}\mathfrak{A}\subseteq\mathfrak{F}\subseteq\mathfrak{N}%
\mathcal{A}}

.
We prove that G is soluble and the derived subgroup of each metanilpotent subgroup
is nilpotent. We also describe the structure of groups
in which every Sylow subgroup is

𝔉

{\mathfrak{F}}

-subnormal
or

𝔉

{\mathfrak{F}}

-abnormal.
Evaluating stress corrosion cracking behaviour of high strength AA7075-T651 aluminium alloy
Authors: Prabhuraj P. , Rajakumar S. , Lakshminarayanan A.K. , Balasubramanian V.
Published: November 2017

The objective of the present study is to determine the threshold stress level of stress corrosion cracking (SCC) in AA7075-T651 aluminium alloy by suitable experimentation. The test was carried out using a circumferential notch specimen in a horizontal-type constant load SCC setup in a 3.5 wt.% NaCl solution. The time to failure by SCC was determined at various loading conditions. The threshold stress of AA7075-T651 alloy was found to be 242 MPa in a 3.5 wt.% NaCl solution. The various regions of the fractured surface specimen such as machined notch, SCC region and final overload fracture area were examined using scanning electron microscopy (SEM) in order to identify the SCC mechanism.
Crystal structure of 1-(4-fluorophenyl)-N-(5-((triphenylstannyl)thio)thiophen-2-yl)methanimine, C27H20FN3S2Sn
Authors: Meng Fankun , Jia Junying , Liu Hongsheng
Published: November 2017

C27H20FN3S2Sn, monoclinic, P21/n (no. 14), a = 15.631(4) Å, b = 9.865(3) Å, c = 17.256(3) Å β = 108.335(11)°, V = 2525.8(10) Å3, Z = 4, R
gt(F) = 0.0398, wR
ref(F
2) = 0.0917, T = 298 K.
Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines
Authors: Stompor Monika , Świtalska Marta , Wietrzyk Joanna
Published: November 2017

The synthesis of hydroxyflavone derivatives is described. The acyl derivatives of 3-, 6-, 7-hydroxyflavones (compounds 2, 4, 6, respectively) and chrysin (5,7-dihydroxyflavone, 7) were obtained in high yields and evaluated in vitro for their cytotoxic activity against several cancer cell lines of different origin: MCF-7 (breast cancer), A549 (nonsmall cell lung cancer), MES-SA (uterine sarcoma), LoVo (colon cancer), drug-resistant human cancer cells (MES-SA/DX5, LoVo/DX) and also towards non-cancer cell line MCF-10A (normal breast epithelial cells). The flavones modified with acyl group showed higher antiproliferative activity than free hydroxyflavones. The highest activity was noted for 3-acetoxyflavone (2), which proved active against LoVo, LoVo/DX, and MES-SA cell lines (IC50 from 4.7 μM to 7.8 μM, respectively). The highest ability to overcome the barrier of resistance (resistance index=0.82) against the drug-resistant MES-SA/DX5 cells compared to the parental drug-sensitive MES-SA cell line was found for 7-acetoxyflavone (6).
A Sustainability Strategy Assessment Framework Model for Medical Tourism Supply Chain in Asia
Authors: Chung K.-C. , Chang L.-C.
Published: November 2017

This study developed a sustainability policy evaluation for medical tourism supply chain (MTSC) that is validated using the Delphi method and the analytical network process (ANP). This study assessed the criteria through expert survey method by five experts from the government, the academe, and the industry. Results showed that the financial perspective is the heaviest among the criteria, indicating unanimous agreement of the experts and scholars that a healthy financial situation is necessary to integrate the MTSC. This study can provide criteria and correct the overall performance for MTSC entrepreneurs and scholars. Lastly, the conclusion provided MTSC-related insights and suggestions.
Ahuna and the Moʹo
Authors: Katz Julia
Published: November 2017

This article explores the socioeconomic phenomenon of Chinese migrants capitalizing on indigenous Hawaiian foodways around the turn of the twentieth century. By examining fishponds and poi factories, I investigate multiple strategies of survival and success including community organization, interracial communion, and cultural appropriation. I use family histories and territorial reports to reconstruct a history of Chinese and Hawaiian economic intimacy and argue that certain ventures that have been recorded as categorically “Chinese” must be reinterpreted as creolized. These joint enterprises, which combined diasporic networks of labor and capital with indigenous knowledge and resources, demonstrate an alternative path from plantation capitalist modernity. I conclude that credit must be restored to indigenous participants when evaluating the success of migrant enterprise.
Kompetencije učitelja biologije za izradu računalnih sadržaja i uporabu informacijsko-komunikacijskih tehnologija
Authors: Bulić Mila , Novoselić Daniela
Published: November 2017

Današnji učitelji biologije trebaju biti stručni, informatički i informacijski kompetentni, sposobni osmišljavati raznovrsne nastavne scenarije i primjenjivati suvremene tehnologije omogućujući učenicima stjecanje znanja i razvijanje kompetencija potrebnih za život u 21. stoljeću. S ciljem utvrđivanja razine implementacije informacijsko-komunikacijske tehnologije (IKT) u odgojno-obrazovnom procesu provedeno je istraživanje na uzorku od 65 učitelja biologije Splitsko-dalmatinske županije. Dobiveni rezultati pokazuju kako učitelji biologije nedovoljno primjenjuju IKT alate, a u radu najčešće koriste Power Point prezentacije i njihove permutacije. Radni staž učitelja te vrsta škole u kojoj rade nisu čimbenici učestalije uporabe IKT alata u odgojno-obrazovnom procesu. Dobiveni rezultati mogu biti poticaj za preoblikovanje inicijalnog obrazovanja budućih učitelja biologije te smjernica za potrebno dodatno profesionalno usavršavanje učitelja praktičara i jačanje njihovih IKT kompetencija.
The Evidence from Nin concerning Bishop Natalis (1436 – 1462), Apostolic Legate to Bosnia
Authors: Jakšić Nikola
Published: November 2017

The article deals with two historical artefacts from the mid-fifteenth century: an episcopal coat of arms, and a large ring with a crest and inscription of Pope Pius II (Enea Silvio Piccolomini). It argues for a direct connection between both artefacts and Bishop Natalis, who carriedout his pastoral duties in Nin from 1436 to 1462. The coat of arms used to be set into the wall above the entrance to the former Episcopal Palace, and the ring with a papal crest is a direct testimony of Natalis’ service as an apostolic legate to Bosnia, a responsibility with which he was entrusted during the final years of his life.
Additive Phenotypes Underlie Epistasis of Fitness Effects
Authors: Sackman Andrew M , Rokyta Darin R
Published: November 2017

Gene interactions, or epistasis, play a large role in determining evolutionary outcomes. The ruggedness of fitness landscapes, and thus the predictability of evolution and the accessibility of high-fitness genotypes, is determined largely by the pervasiveness of epistasis and the degree of correlation between similar genotypes. We created all possible pairings of three sets of five beneficial first-step mutations fixed during adaptive walks under three different regimes: selection on growth rate alone, on growth rate and thermal stability, and on growth rate and pH stability. All 30 double-mutants displayed negative, antagonistic epistasis with regard to growth rate and fitness, but positive epistasis and additivity were common for the stability phenotypes. This suggested that biophysically simple phenotypes, such as capsid stability, may on average behave more additively than complex phenotypes like viral growth rate. Growth rate epistasis was also smaller in magnitude when the individual effects of single mutations were smaller. Significant sign epistasis, such that the effect of a mutation that is beneficial in the wild-type background is deleterious in combination with a second mutation, emerged more frequently in intragenic mutational pairings than in intergenic pairs, and was evident in nearly half of the double-mutants, indicating that the fitness landscape is moderately uncorrelated and of intermediate ruggedness. Together, our results indicated that mutations may interact additively with regard to phenotype when considered at a basic, biophysical level, but that epistasis arises as a result of pleiotropic interactions between the individual components of complex phenotypes and diminishing returns arising from intermediate phenotypic optima.
New Drugs for the Treatment of Heart Failure
Authors: Bindra Amarinder ,   Baylor University Medical Center, Dallas, TX; Texas A&M Health Science Center, College of Medicine, Dallas, TX, Hall Shelley A ,   Baylor University Medical Center, Dallas, TX; Texas A&M Health Science Center, College of Medicine, Dallas, TX
Published: November 2017

Angiotensin receptor-neprilysin inhibitor, Entresto® (Novartis), a combination of sacubitril and valsartan, and funny channel inhibitor of the sinoatrial node, Corlanor® (Amgen), are two new drugs that have been Food and Drug Association-approved for treatment of symptomatic heart failure patients. Their mechanisms of action differ from each other and from the heart failure drugs available prior to their approval. Reduction in mortality is the hallmark of Entresto, while reduction in hospitalizations was the common denominator of both Entresto and Corlanor. These drugs are generally well tolerated and are widely used by heart failure cardiologists. Another promising agent, omecamtiv mecarbil, a myosin activator, is currently under trials, while RLX030, a relaxin receptor agonist, did not meet primary endpoints in a study.
Reseña de: Los nuevos amos de la tierra: Land Grabbing (Liberti, 2015)
Authors: Ochoa Germán Ignacio
Published: November 2017

Stefano Liberti. 2015. Los nuevos amos de la tierra. Land Grabbing. Bogotá: Penguin Random House Grupo Editorial. 250 pp. ISBN: 9788430616886. [Título original en italiano: Land Grabbing. Come il mercato delle terre crea il nuovo colonialismo].
Reseña de: Capitalism in the Web of Life: Ecology and Accumulation of Capital (Moore, 2015)
Authors: Palacio Germán
Published: November 2017

Jason Moore. 2015. Capitalism in the Web of Life. Ecology and Accumulation of Capital [Capitalismo en la red de la vida. Ecología y acumulación de capital]. London  New York: Verso Books. 336 pp. ISBN 978-1781689028.
Reseña de: Guardianes de la selva o La odisea del gobierno propio y de la autonomía amazónica (von Hildebrand y Brackelaire, 2012)
Authors: Chapuis Oceane
Published: November 2017

Martin von Hildebrand & Vincent Brackelaire. 2012. Guardianes de la selva. Gobernabilidad y autonomía en la Amazonia colombiana. Bogotá: GAIA. 248 pp. ISBN: 9789589773062.
Self-perceived social status: its relation to aggression and personality traits in two Spanish speaking samples
Authors: Monge-López David , Álvarez-Solas Sara
Published: November 2017

Dominancia y prestigio se han propuesto como estrategias para alcanzar estatus en humanos. La dominancia es el uso de amenazas y agresión, y el prestigio es la búsqueda de logros culturales. Esta investigación fue llevada a cabo utilizando cuestionarios en muestras de habla hispana: Madrid (España) y San José (Costa Rica). La dominancia y el prestigio auto-percibidos fueron correlacionados con dimensiones de la agresión y los cinco grandes rasgos de personalidad. Un componente que agrupó las subescalas de agresión y la afabilidad fue el mejor predictor de la dominancia en ambos sexos de ambos países. El prestigio fue predicho por la escrupulosidad y la extroversión en sendas muestras y por bajas puntuaciones en hostilidad y neuroticismo en hombres españoles.
La perpetuación del comportamiento antisocial de los jóvenes caboverdianos: un estudio predictivo
Authors: Dias Jorge , Formiga Nilton , Gonçalves Rui Abrunhosa , Cunha Olga , Conde Rita
Published: November 2017

En Cabo Verde, desde finales de los años 90, se asiste a un creciente aumento del comportamiento antisocial de los jóvenes con edades comprendidas entre los 12 y los 21 años. Sin embargo, el conocimiento de los factores que causan y  perpetúan tal comportamiento es aún muy incipiente. Este estudio busca identificar los factores que pueden predecir el comportamiento antisocial reportado en Cabo Verde, utilizando para tal fin, el International Self-Report Delinquency Study -3,  (ISRD-3). La muestra estuvo constituida por 535 estudiantes de ambos sexos que asisten a la escuela pública en Cabo Verde, siendo 284 (53%) del sexo femenino y 247 (46.25%) del sexo masculino. La edad de los jóvenes varía entre los 13 y los 21 años, con una media de edad de 16.66 y una desviación estándar de 2.04. Los resultados indican que el sexo es un fuerte predictor de la perpetración de comportamientos antisociales, siendo que los individuos del sexo masculino revelan una mayor probabilidad de involucrarse en comportamientos antisociales. Los adolescentes con menos actitudes antisociales son también los que tienen menores probabilidades de envolverse en comportamientos antisociales. Del mismo modo, aunque sólo se revele marginalmente significativa, los adolescentes que relatan una mayor implicación en actividades antisociales se muestran más propensos a ocupar su tiempo libre en actividades perjudiciales. Estos resultados son analizados en términos de sus implicaciones para la prevención de la delincuencia.
Características empreendedoras associadas ao desempenho de micro, pequenas e médias EBTs do setor de TIC em Ribeirão Preto
Authors: Da Cunha Bomfim Eliza Maria , Torkomian Ana Lúcia Vitale
Published: November 2017

A importância do empreendedorismo em uma sociedade é amplamente conhecida devido à sua influência no crescimento e desenvolvimento dos países. Empresas de Base Tecnológica, como as do setor de Tecnologia da Informação e Comunicação, são uma importante fonte de novos empregos e fornecem um estímulo crucial para as economias nacionais. Para essas empresas, crescimento rápido é geralmente uma indicação de ampla aceitação de seus produtos ou serviços no mercado. No entanto, mesmo após vários anos de funcionamento, muitas EBTs ainda têm dificuldades em melhorar seus desempenhos. Nesse contexto, esse artigo tem por objetivo avaliar as características empreendedoras de proprietários-gerentes de seis micro, pequenas e médias empresas do setor de TIC na cidade de Ribeirão Preto – SP, buscando traçar um paralelo com o desempenho de seus negócios. A partir dos questionários aplicados, verificou-se a existência de traços empreendedores em maior escala entre os empresários mais bem-sucedidos, reafirmando, para esses casos, os indícios literários que preconizam ser este um importante fator para um melhor desempenho das organizações.
O Impacto da Crise de Crédito de 2008 no Setor Sucroenergético: Um Estudo Econométrico
Authors: Camioto Flávia de Castro , Moralles Herick Fernando , Machado Rafael
Published: November 2017

O setor sucroenergético contribuiu com, aproximadamente, 2% do Produto Interno Bruto brasileiro, além de gerar mais de 600 mil empregos em cerca de mil municípios. Considerando a relevância desse setor, o presente trabalho tem como objetivo determinar as principais variáveis que impactam o crescimento do setor sucroenergético brasileiro. Para isso, foram utilizadas técnicas econométricas que quantificaram o impacto de cada variável estudada no crescimento do Produto Interno Bruto desse setor, entre 1980 e 2013. Foi realizada também uma análise do impacto da crise de crédito de 2008 no seu crescimento. Os resultados indicam que as variáveis que impactam o crescimento do setor sucroenergético são: taxa de câmbio, consumo de álcool carburante e preço médio do barril de petróleo. Além disso, verificou-se que a crise de 2008 contribuiu negativamente para o seu PIB. Ademais, verificou-se que a crise nesse setor teve origem com o otimismo do setor, devido ao grande crescimento dele em 2006 e aos fatores globais no ano de 2008. Isso se refletiu nas variáveis estudadas, como taxa de câmbio e o consumo de álcool carburante, que acabaram por impactar negativamente o crescimento desse setor.
Aplicação do DMAIC e Análise de Falhas de Embalagens Metálicas na Indústria de Conservas
Authors: Souza Rafael Santos , Ferreira Porto Rosa Ariane , Porciúncula Gilson Simões , Dos Santos Gilberto Tavares
Published: November 2017

Na indústria de alimentos a garantia da qualidade está fortemente associada com a segurança do consumidor e com os riscos de comprometimento da sanidade dos produtos. Especificamente nas indústrias de conservas, latas enferrujadas, amassadas ou estufadas podem conter bactérias e ocasionar infecções alimentares. Este artigo aborda a aplicação do DMAIC e a análise de falhas para reduzir a quantidade de latas amassadas em uma indústria de conservas. A metodologia usada foi de natureza aplicada, com objetivo exploratório, abordagem quali-quantitativa e o método foi a realização de um estudo de caso. Através de análises estatísticas verificou-se elevada quantidade de embalagens amassadas no processo produtivo constituído das etapas de envase, recravação e encestamento. A etapa com a maior quantidade de latas amassadas entre as três etapas foi a recravação. Na sequência, aplicou-se FMEA para análise de falhas relacionadas à utilização da máquina de recravação automatizada. Finalmente, um plano de ação foi proposto para solucionar o problema das latas amassadas na etapa de recravação e os resultados obtidos demonstram as melhorias obtidas abaixo da meta após 4 meses (de agosto a novembro de 2015).
Using the Dundee Polyprofessionalism Inventory I: Academic Integrity to Map Student Professionalism in 3 Arab Gulf Countries
Authors: Al-Qahtani Mona , Roff Sue
Published: November 2017

This article was migrated. The article was marked as recommended. Background: Teaching professionalism and communication skills have become an integral part of medical education. But professionalism cultures may themselves be at least partially culturally determined. It would be helpful to be able to 'map' regional professionalism cultures especially in an era of increasing globalisation and international mobility of practising doctors within and across regional boundaries. Objectives: To explore medical students' views in three Arab Gulf countries (Kingdom of Saudi Arabia, United Arab Emirates, and Bahrain) of the appropriate sanctions for a one-time infraction in 34 unprofessional behaviors relating to academic integrity as a proxy for their perception of the relative importance of specific items of poor professionalism. Methods: In a cross-sectional study, the Dundee Poly-professionalism Inventory I was administered to 2nd, 3rd, 4th, and 5th undergraduate medical students in three colleges of medicine at governmental universities in three Arab Gulf countries. Data were analyzed using descriptive and inferential statistics. Results: There was extensive congruence and near congruence in the median recommended sanctions from the three sub-groups. Several areas of concern about respondents' perceptions of the importance of lapses in professionalism are identified. Conclusion: The results suggest that the Dundee Polyprofessionalism Inventory I can be used to map the professional culture in medical schools in the Gulf states which seem to share a common culture. More research is needed about the implications for learning and teaching student professionalism.
Wealth of Wisdom Generated by the Scientist Rimantas Kontvainas
Authors: Barkauskaitė Marijona
Published: November 2017

The publication presents some of the significant writings of the scientist, geographer, active public figure who contributed to the efficient functioning of Lithuanian University of Educational Sciences in promoting the university and its constant improvement by educating teachers, managers and young scientists for educational institutions, through which career paths lead teachers to become not only educational policy-makers, but also statesmen and stateswomen.