bluuebunny/crossref_metadata_2025 huggingface dataset:
A review of defect engineering, ion implantation, and nanofabrication using the helium ion microscope
Authors: Allen Frances I
Published: July 2021

The helium ion microscope has emerged as a multifaceted instrument enabling a broad range of applications beyond imaging in which the finely focused helium ion beam is used for a variety of defect engineering, ion implantation, and nanofabrication tasks. Operation of the ion source with neon has extended the reach of this technology even further. This paper reviews the materials modification research that has been enabled by the helium ion microscope since its commercialization in 2007, ranging from fundamental studies of beam–sample effects, to the prototyping of new devices with features in the sub-10 nm domain.
THE COMPARATIVE ANALYSIS OF RUSSIAN AND KOREAN INTONATION
Authors: Ефремова М.Ю.
Published: July 2021

Данная статья рассматривает особенности русской интонации в сопоставлении с корейской при взаимодействии лексики, синтаксиса, интонации и контекста, а также их употребление в нейтральных и эмоционально-окрашенных конструкциях. Соотношение нейтрального и эмоционально-окрашенного может не совпадать. В русском языке возможности коммуникативного анализа предложения раскрываются наиболее полно именно в звучащей речи, где интонация играет важную роль. Она передает различные оттенки значений, которые в корейском языке часто выражаются лексически. В русских словарях мало примеров использования интонационных конструкций и перевода на другие языки, хотя именно они играют важную смыслоразличительную роль в звучащей речи.

This article considers the features of Russian intonation in comparison with Korean in the interaction of vocabulary, syntax, intonation and context, as well as their usage in neutral and emotionally-colored constructions. The ratio of neutral and emotionally-colored constructions may not match. In Russian language the possibilities of communicative analysis of a sentence are revealed most fully in the spoken speech, where intonation plays an important role. Intonation conveys various shades of meaning that are often expressed lexically in Korean. In Russian dictionaries, intonation constructions, examples of their usage and translation into other languages are not represented enough, although they play an important role in the meaning-distinguishing speech.
Pengaruh Persepsi Kualitas Pelayanan dan Persepsi Nilai Terhadap Kepuasan Serta Dampaknya Pada Loyalitas Pelanggan Maskapai Penerbangan
Authors: Budiansari Annisa , Sujana Sujana
Published: July 2021

This study aims to determine : The effect of perception of service quality on customer satisfaction, The effect of customer value perception on customer satisfaction, and And the impact of customer satisfaction on customer loyalty. This study uses the independent variable (service quality perception, customer value perception), and the dependent variable (customer satisfaction and customer loyalty). The sample method used in this study is the roscoe method and the Analysis Tool used in this study is AMOS version 23. With the number of 200 respondents selected are people who have used Batik Air Indonesia's flight services in the city of Bogor. Based on the research, it can be concluded that there are three hypotheses that have positive and significant influence, namely: The first hypothesis is the perception of service quality and customer satisfaction has an influence and significant with the results of the t-test of 4.039 greater than t-table. The second hypothesis is the perception of customer value on customer satisfaction has an influence with a negative t-test that is equal to -1.529 smaller than t-table. The third hypothesis is customer satisfaction Customer loyalty has a positive and significant impact with the t-test result of 4.039 greater than t-table.

 

Keywords: Perception, influence, impact, Service Quality, Customer Value, Customer Satisfaction, Customer Loyalty, Batik Air Indonesia.
Analysis of calculations when creating a theoretical drawing of a tug by the interpolation method
Authors: Davydova Svetlana V. , Andriyanov Ivan V. Andriyanov
Published: July 2021

The development of a theoretical drawing by manual methods is notable for considerable laboriousness, in this regard, the use of methods that significantly reduce the development time and increase its quality is relevant. In this work, a comparative analysis of methods for obtaining ordinates of a theoretical drawing is carried out. The existing methods of computer-aided design and methods of forming a theoretical drawing are considered: classical, interpolation, affine transformation method, modular method. The process of development of the surface of the tug by the interpolation method is shown, the substantiation of its application is carried out. On the basis of the developed model, a program for calculating the ordinates of the theoretical drawing of tugboats was developed. The results of the software package operation are presented, namely, the ordinates of the theoretical drawing of the tugboat and the hull of the theoretical drawing, as well as the analysis of the calculation accuracy. The adopted approach to the development of the ship's surface can significantly reduce the time and cost of design work on the development of the ship's surface, can be used for its further automation and use as scientific, industrial and educational purposes.
Pendidikan Keluarga Kristen dalam Mencegah Kenakalan Remaja
Authors: Nono Marten Malo
Published: July 2021

Christian Family Education is a God-centered education and is based on Biblical teaching. According to Deuteronomy 6:6-9, education is done by continuously teaching God's word. Christian family education is also directed education with excellent educational methods to do and apply in Christian families. Education in Christian families is needed to deal with juvenile delinquency. Based on the explanation above, it is necessary to develop regular education in the family through formal and non-formal theological education, hold regular retreats for Christian families, hold regular fellowships between family members, and build prayer altars at home to strengthen fellowship between family members and increasingly active in providing family members with regular and repeated Bible education and study.Pendidikan Keluarga Kristen adalah pendidikan yang berpusat pada Allah dan dasar pengajarannya yang Alkitabiah. Menurut kitab Ulangan 6:6-9 adalah pendidikan dilakukan dengan terus menerus mengajarkan firman Tuhan. Pendidikan keluarga Kristen juga merupakan pendidikan terarah dengan metode pendidikan yang sangan baik untuk di lakukan dan di terapkan dalam keluarga Kristen. Diperlukan pendidikan dalam keluarga Kristen untuk menanggulangi kenakalan anak remaja. Berdasarkan penjelasan di atas, maka perlu dikembangkan pendidikan secara rutin dalam keluarga melalui pendidikan teologi secara formal maupun nonformal, mengadakan retret secara berkala bagi keluarga Kristen, mengadakan persekutuan yang rutin antar anggota keluarga, dan membangun mazbah doa di rumah untuk mempererat persekutuan antar anggota keluarga dan semakin giat untuk memperlengkapi anggota keluarga dengan pendidikan dan pendalaman Alkitab secara rutin dan berulang-ulang.
INTEGRATING REMOTE-SENSED AND HISTORICAL GEODATA TO ASSESS INTERACTIONS BETWEEN RURAL BUILDINGS AND AGROFORESTRY LAND
Authors: Cillis Giuseppe , Statuto Dina , Picuno Pietro
Published: July 2021

The rural built heritage constitutes a unique example, due to architectural and technical issues, which plays a central role in the formation of rural landscape. In this research, interactions between rural buildings and the surrounding land have been examined. Two case studies exemplifying some of typical dynamics of some internal mountain areas of Mediterranean region have been considered. These areas are located in Basilicata Region (Southern Italy) and suffer from land and rural buildings heritage abandonment, as well as from the concurrent disappearance of agroforestry systems with high ecological value. A multi-chronological geo-database incorporating different land cover datasets over a period of 62 years (1955–1988–2008–2017) has been implemented into a GIS to assess relationships between some rural buildings and the surrounding land have been then assessed. This has been achieved by integrating different types of remote-sensed geodata: historical aerial photos, digital orthophotos and satellite images. The analyses carried out have shown that the intensity of land abandonment can also be related to the type of rural building and prevalent agricultural activity. Moreover, thanks to this methodology, it has been possible to produce several spatial information useful to support public decisionmakers at different level.
The Effect of Learning Module Program on Mothers’ Ability to Adapt to New Foods, Feeding Styles, and Self-efficacy to Their Children with Avoidant Restrictive Food Intake Disorder
Authors: Prasetyo Yoyok Bekti , Dewi Yulis Setiya , Arifin Hidayat , Kamel Amel Dawod
Published: July 2021

BACKGROUND: The education to improve a mother’s knowledge is deemed to be important because it may improve children’s nutritional status.
AIM: The aim of this study was to examine the effects of learning module program on the mothers’ ability to adapt to new foods, feeding styles, and self-efficacy to their children with avoidant restrictive food intake disorder (ARFID).
METHODS: Quasi-experimental design was used to evaluate the effectiveness of learning module program. Fifteen mothers of experimental group were given four meetings within 4 weeks. Each meeting ran about 50 min. Fifteen mothers of control group were conducted home visit and received twice education about the health principals of feeding children. Both experimental group and control group had pre-test and post-test. The data were analyzed using Chi-square test, Fisher’s exact test, and Mann–Whitney U-test.
RESULTS: The participants of the experimental group have shown bigger surge of new foods adaptation (t = –2.973, p < 0.003), feeding style (t = –4.646, p < 0.001), self-efficacy (t = –3.652, p = 0.001) than the control group has.
CONCLUSION: The findings indicated that the learning module program was deemed to be effective to improve mothers’ ability to adapt to new foods, feeding styles, and self-efficacy to their children with ARFID.
On the “cartilaginous rider” in the endocasts of turtle brain cavities
Authors: Werneburg Ingmar , Evers Serjoscha W. , Ferreira Gabriel
Published: July 2021

Abstract

In recent years, paleoneurology became a very popular research field and hundreds of brain-endocasts were described. The interpretation of a dorsal protuberance of the brain-endocast puzzled researchers for a long time, the so-called (cartilaginous) rider. This is mainly because of technical limitations in the past and due to non-accessibility of comparative material. Using turtles as a case-study, we conducted a literature review and studied embryological data in addition to fossil and extant species’ endocasts. We assessed three hypotheses on the origin of the rider as relating to 1) the pineal gland, to 2) the blood vessel system, and to 3) skull roof elements. Based on our integrated anatomical observations, we refute the pineal gland hypothesis (1) and an exclusive blood vessel explanation (2). However, we show that, in most cases, the cartilaginous origin applies (3). The related cartilages, mainly the anterior process of the chondrocranial tectum synoticum, can persist until adulthood. Its diversity is interpreted in regard to the mechanical support for the temporal skull region, the shape of which has been shown to be in turn related to neck retraction and jaw mechanics. Finally, we highlight the value of embryological data to provide profound hypotheses for evolutionary research despite its low quantitative evaluability. We argue that it should be studied in conjunction with modern computer-aided data acquisition whenever possible.
Le charme discret de la mixité
Authors: Piganiol Marie
Published: July 2021

Les écoquartiers, en vogue dans les villes françaises depuis la fin des années 2000, présentent la spécificité d’être à la fois socialement mixtes et habités par une part substantielle de ménages bourgeois. Ceux-ci y occupent des logements onéreux entourés d’habitat social, alors que d’ordinaire, ils redoutent leur proximité et préfèrent l’entre-soi des quartiers cossus. Comment expliquer ce paradoxe ? Enquêtant sur la fabrique concrète d’un écoquartier parisien, cet article analyse les ressorts politiques et économiques d’une mixité inhabituelle. L’argument proposé est qu’en focalisant la politique de mixité sur le logement social, les élus abandonnent le peuplement des logements privés aux promoteurs. Privilégiant des logements haut de gamme, jugés plus lucratifs, les promoteurs ont ciblé les ménages les plus solvables, conduisant les urbanistes et les architectes à ajuster le quartier à ces habitants peu familiers de la mixité. Ces derniers ont rendu la mixité discrète à l’intérieur du quartier et travaillé au caractère distinctif des espaces publics et privés, conformément aux aspirations des classes supérieures.
Apaiser l’émeute : analyse d’un schéma narratif
Authors: Chevalier Clara
Published: July 2021

En entendant « réprimer » au sens qui est d’abord le sien au 18 e  siècle, celui de « contenir », cet article traite d’un type de réponse à l’émeute consistant en tentatives d’« apaisement » – selon le mot des sources – de la part des autorités. L’analyse de récits d’interventions d’apaisement présentées comme exemplaires – dans le Traité de la police de Delamare et dans des écrits sur l’action du maréchal de Boufflers à Paris en 1709 – permet de faire apparaître les principaux traits d’un schéma narratif. Celui-ci renvoie à un modèle de maintien de l’ordre fondé sur l’autorité et la perfection morale associées aux magistrats, qui demeure valorisé tout au long du siècle.
Le peuple après la colère
Authors: Renard Margot , Noûs Camille
Published: July 2021

Lorsque le peintre d’histoire Paul Delaroche représente Les vainqueurs de la Bastille entre 1830 et 1838, il ne s’est encore jamais intéressé à la Révolution de 1789. Il traite le sujet – l’insurrection d’une partie du peuple parisien contre la prison royale, symbole de l’oppression féodale – dans le contexte d’une commande de quatre œuvres pour l’Hôtel de Ville de Paris, destinées à honorer le rôle historique du peuple. En 1830, où intervient une nouvelle révolution, celle des Trois Glorieuses, l’événement est encore vif dans la mémoire collective, et les historiens commencent tout juste à le traiter comme un fait historique majeur dans l’histoire de France. Ce regard de Paul Delaroche, peintre du 19 e  siècle romantique, sur la chute de l’Ancien Régime, est donc intéressant pour son écho politique, pour son positionnement artistique – représenter le peuple après la colère – et pour son rôle dans la formation d’un imaginaire collectif de la Révolution au 19 e  siècle.
Jus et Potestas
Authors: Francioni Gianni , Noûs Camille
Published: July 2021

Dans le §  xxviii des Délits et des peines , Beccaria soutient que, dans un État de droit, la peine de mort n’est ni légitime, ni nécessaire, ni utile. Dans un passage qu’il n’est pas facile d’interpréter, il évoque cependant le cas d’un homme qui, quoique prisonnier, constitue pourtant, par ses relations et sa puissance, une telle menace pour la sécurité de la nation que seul l’échafaud représente alors un remède nécessaire. Mais cette situation, qui évoque entre les lignes celle d’un souverain déposé, ne désigne pas un état d’exception où seraient suspendues les règles « normales » de la société politique. Elle décrit plutôt le retour à un véritable « état de guerre », où « les désordres tiennent lieu de lois ».
L’efficacité de l’évaluation d’impact sur la santé : leçons tirées d’une expérience dans l’agglomération bordelaise
Authors: Rivadeneyra-Sicilia Ana , Rivadeneyra-Sicilia Ana
Published: July 2021

Introduction : Ce travail présente les résultats d’une évaluation de l’efficacité d’une évaluation d’impact sur la santé (EIS) menée sur un projet d’aménagement urbain. L’objectif de l’évaluation était d’apprécier les effets directs de l’EIS sur le processus décisionnel par la prise en compte des recommandations ainsi que ses effets indirects en termes d’appropriation et d’utilisation des connaissances produites par les différentes parties prenantes. Méthodes : Douze entretiens semi-directifs ont été menés auprès de décideurs municipaux, de directeurs de services de santé publique de l’agence régionale de santé et d’agents des équipes techniques des collectivités ayant contribué à l’EIS. Résultats : Les récits recueillis font état des effets indirects de l’EIS quant au renforcement des valeurs et des croyances relevant d’une vision holistique de la santé, des évolutions des pratiques professionnelles par une appropriation des connaissances produites et du renforcement des collaborations intersectorielles en faveur de la santé. Des résultats plus modestes ont été recensés quant à l’efficacité de l’EIS à influencer le processus décisionnel à travers la prise en compte des recommandations en raison de leur caractère redondant avec les pratiques routinières des équipes techniques et de leur temporalité tardive. Néanmoins, l’intérêt exprimé à capitaliser les recommandations sur de futurs projets municipaux et métropolitains suggère des effets différés à ne pas négliger. Conclusions : Cette étude apporte de nouvelles données sur l’efficacité, à des degrés différents, de l’une des premières EIS menées en Nouvelle-Aquitaine. D’autres évaluations des EIS seraient à promouvoir en France afin d’apprécier l’utilité de la démarche et tirer des enseignements utiles pour la poursuite de son déploiement et la consolidation de sa pratique dans les années à venir.
Similitudes et différences entre l’évaluation d’impact sur la santé et l’évaluation de politiques publiques
Authors: Jabot Françoise , Massot Caroline
Published: July 2021

Introduction : L’évaluation d’impact sur la santé (EIS) se développe rapidement en France. Elle est proche d’autres démarches, telles que l’évaluation de politiques publiques (EPP) avec laquelle elle est parfois confondue. But de l’étude : Cet article a pour objectifs d’identifier les similitudes et différences entre EIS et EPP et d’apprécier dans quelle mesure les compétences en EPP sont transférables pour l’EIS. Résultats : Les deux démarches présentent des traits communs : elles sont basées sur des principes et valeurs structurant la pratique ; elles produisent un jugement au terme d’un processus d’argumentation ; elles suivent le même processus intellectuel et utilisent des outils similaires. Cependant, l’EIS présente des spécificités qui justifient le renforcement des compétences notamment en lien avec sa dimension participative. Conclusions : Les deux démarches présentent plus de similitudes que de différences en raison de leur nature évaluative. Les compétences acquises en EPP sont transférables à l’EIS et l’évaluateur à la croisée des deux exercices peut revisiter et enrichir sa pratique en EPP.
Intégration de la santé mentale dans les services de soins de santé primaires en République démocratique du Congo
Authors: Mukala Mayoyo Erick , van de Put Willem , Van Belle Sara , van Mierlo Bibiane , Criel Bart
Published: July 2021

Objectifs : Cet article vise à documenter l’expérience d’intégration d’un programme d’offre de soins de santé mentale dans les services de soins de santé primaires du district de Lubero en République démocratique du Congo (RDC) entre 2011 et 2015, et à analyser l’accès et l’utilisation des services de santé mentale. Méthode : Il s’agit d’une étude rétrospective utilisant un design d’étude de cas. Les données collectées dans les différents documents du projet et l’analyse documentaire des textes normatifs venant du ministère de la Santé publique ont permis d’analyser les résultats d’intégration. Résultats : Les résultats indiquent que 3 941 patients ayant un problème de santé mentale ont utilisé les soins offerts aux centres de santé (CS) et à l’hôpital du district entre 2012 et 2015. En 2015, le taux d’utilisation moyen des soins curatifs dans les CS pour des problèmes de santé mentale était de 7 nouveaux cas pour 1 000 habitants par an. La majorité de ces patients ont été pris en charge en ambulatoire, en première ligne de soins. Discussion : Notre étude montre qu’il est possible d’intégrer la santé mentale dans les services de santé en RDC. Néanmoins, les grands problèmes en termes d’accès et d’utilisation des soins de base indiquent que la réussite d’une telle initiative d’intégration est tributaire de la qualité du système de santé en place et de l’implication d’un éventail d’acteurs sanitaires et non sanitaires, y compris des personnes clés au sein des communautés.
Des enjeux relatifs à la taxation du tabac dans les pays de la Cédéao
Authors: Ane Mohamed
Published: July 2021

Cet article propose une réflexion sur les politiques de régulation de la consommation du tabac dans les pays de la Communauté économique des États de l’Afrique de l’Ouest (Cédéao). L’argumentation est construite à partir de l’approche économique coût-bénéfice. Il en ressort que, même si les politiques fiscales et tarifaires sont nécessaires pour diminuer la demande de tabac, celles-ci doivent permettre de renforcer les politiques d’information et de sensibilisation pour une approche globale de lutte contre le tabagisme, notamment passif. Il suggère ainsi d’inventer de nouvelles formes de régulation qui s’inscrivent dans une logique de promotion et d’éducation à la santé pour les personnes dépendantes et/ou pauvres car ces dernières modifient difficilement leur comportement à la suite d’une hausse des prix de la drogue.
Lessons Learned from Developing Plain Language Summaries of Research Studies
Authors: Maurer Maureen , Siegel Joanna E. , Firminger Kirsten B. , Lowers Jane , Dutta Tania , Chang Jane S.
Published: July 2021

Background:

Plain language translation may facilitate the public's ability to understand and use results of scientific research.

Brief description of activity:

This article describes the Patient-Centered Outcomes Research Institute's (PCORI) approach to and lessons learned from developing plain language summaries of PCORI-funded research for the lay public.

Implementation:

We developed and tested a standard template for the summaries, incorporating feedback in the template design from focus groups with members of the public. Between February 2017 and March 2020, we completed translation of 272 plain language summaries of PCORI-funded studies, covering topics including cardiovascular disease, obesity, cancer, mental health, asthma, HIV/AIDS, and comparative effectiveness research methods.

Results:

Templates use a question-and-answer format, with sections on the rationale, methods, results, limitations, and how the research will help inform decisions. In addition to feedback on template heading wording and order, focus group participants stressed the importance of establishing relevance and conveying credibility and limitations.

Lessons learned:

Lessons learned relate to supporting consistency across individual summaries, carefully prioritizing content to include in the summaries, and balancing plain language and reading level with precision. These lessons learned from template development and implementation may be useful to other organizations or publishers contemplating similar efforts to make scientific research results more accessible.

[
HLRP: Health Literacy Research and Practice
. 2021;5(2):e155–e161.]

Plain Language Summary:

The Patient-Centered Outcomes Research Institute (PCORI) funds comparative effectiveness research. This research compares the benefits and harms of two or more health care choices. In this article, we describe lessons learned from PCORI's efforts to develop plain language summaries of results from the research it funds. These lessons may help other organizations that want to share research results in plain language.
Did the Timing of State Mandated Lockdown Affect the Spread of COVID-19 Infection? A County-level Ecological Study in the United States
Authors: Trivedi Megh M. , Das Anirudha
Published: July 2021

Objectives: Previous pandemics have demonstrated that several demographic, geographic, and socioeconomic factors may play a role in increased infection risk. During this current coronavirus disease 2019 (COVID-19) pandemic, our aim was to examine the association of timing of lockdown at the county level and aforementioned risk factors with daily case rate (DCR) in the United States.Methods: A cross-sectional study using publicly available data was performed including Americans with COVID-19 infection as of May 24, 2020. The United States counties with >100 000 population and >50 cases per 100 000 people were included. The independent variable was the days required from the declaration of lockdown to reach the target case rate (50/100 000 cases) while the dependent (outcome) variable was the DCR per 100 000 on the day of statistical calculation (May 24, 2020) after adjusting for multiple confounding socio-demographic, geographic, and health-related factors. Each independent factor was correlated with outcome variables and assessed for collinearity with each other. Subsequently, all factors with significant association to the outcome variable were included in multiple linear regression models using stepwise method. Models with best R2 value from the multiple regression were chosen.Results: The timing of mandated lockdown order had the most significant association on the DCR per 100 000 after adjusting for multiple socio-demographic, geographic and health-related factors. Additional factors with significant association with increased DCR include rate of uninsured and unemployment.Conclusions: The timing of lockdown order was significantly associated with the spread of COVID-19 at the county level in the United States.
Increase the Efficiency of IoT Devices by Using the Wireless Power Transmission in the Industrial Revolution 4.0
Authors: Chaari Mohamed Zied , Al-Maadeed Somaya
Published: July 2021

Today's world is evolving toward creating a smart house where a multitude of Internet Of Things (IoT) devices and sensors are interacting to deliver plenty of useful information. Essential to the implementation of this IoT is the design of energy-efficient solutions aiming toward a low-carbon-emission, namely green, society. Many R\&D studies are working on a long-range distance wireless charging that will send microwave energy to powered IoT devices wherever it is in the room and without cords. Wireless power transmission technology is the diffusion of RF power without using any physical support. The vision of future technology is to make the IoT devices charging and powered wirelessly. The objective of the work scope is to combine the wireless power technology with smart IoT and IIoT devices and reduce the turnoff of devices due to battery depletion. In this research paper, we designed and realized a wireless charging device using the fundamentals of microwave radiation. The proposed electronic device takes all parameters above to deliver sufficient energy to charging any IoT devices wirelessly with a maximum power of 5W.
Au-delà de la détection des individus « à risque »
Authors: Baillergeau Évelyne
Published: July 2021

La prévention des violences extrémistes se limite-t-elle au signalement et à la neutralisation des « radicalisés » en devenir ? À l’appui d’observations réalisées dans les villes belges confrontées aux départs vers les terres du djihad, cet article révèle une prévention des violences extrémistes visant plutôt à conjuguer réponse aux inquiétudes liées au terrorisme et promotion de l’inclusion sociale à la marge de la société. L’existence de cette prévention permet de mettre en évidence la diversité des modes d’appréhension du « risque terroriste » et de questionner la nature des savoirs de ce risque et la mobilisation de ces savoirs du risque dans une optique préventive.
Andes imaginarios. El mundo precolombino y Oriente en algunos ensayos del indianismo argentino
Authors: Mailhe Alejandra
Published: July 2021

Este trabajo explora la gravitación imaginaria de Oriente y de la Antigüedad en algunas visiones sobre el mundo andino, producidas entre fines del siglo XIX y e inicios del siglo XX. Analiza las comparaciones que establecen algunos intelectuales entre el legado indígena y el pasado “indoeuropeo”, con la legitimación de las periferias que se inicia entre los indianistas románticos, crece en algunos sectores vinculados al espiritualismo en entresiglos, y se expande a partir de la crisis desatada por la Primera Guerra Mundial.En Argentina, autores como Vicente Fidel López y Henri Girgois subrayan los lazos entre el mundo andino y Oriente, en base a remotos contactos culturales y a formas semejantes de conceptualizar el mundo. Partiendo de Les races aryennes du Pérou (1871) de Vicente Fidel López, este artículo considera especialmente el ensayo El oculto entre los aborígenes de América del Sur (1901) de Henri Girgois, fuertemente influido por el texto previo de López, y muy poco considerado hasta el presente por la crítica.Asimismo, busca contrastar estas perspectivas con la refutación de José Imbelloni, que reacciona contra ese tipo de especulaciones, para consolidar por oposición la validez de la antropología científica. En última instancia, el trabajo busca iluminar las bases esotéricas del indianismo argentino posterior, de autores importantes en los años veinte y treinta como Ricardo Rojas.
Effets déclarés par les acteurs à propos du dispositif « devoirs faits » dans un collège
Authors: Assude Teresa , Millon-Faure Karine , Winder Claire Guille-Biel , Gobert Julie
Published: July 2021

Le dispositif « devoirs faits » a été mis en place dans les collèges depuis l’année 2017. Dans le cadre d’un projet de recherche sur le suivi et l’accompagnement de cette mise en place dans un collège REP + à Marseille, nous nous intéressons à ce que les acteurs (élèves et intervenants) déclarent des effets perçus de ce type de dispositif, des difficultés et obstacles rencontrés.
Les déplacements identitaires d’enseignantes formées à l’étranger s’intégrant dans l’école montréalaise
Authors: Morrissette Joëlle , Demazière Didier
Published: July 2021

En raison de la pénurie actuelle de main d’œuvre au Québec, de nombreux enseignants formés à l’étranger y poursuivre leur carrière. Pour ceux et celles qui viennent de pays très différents, les premières expériences constituent un choc si important qu’elles initient une transformation identitaire. Un dispositif de recherche impliquant des entretiens individuels et de groupe avec 4 d’entre eux, analysés selon une perspective interactionniste, a conduit à identifier trois changements de leur « rapport à soi » : du maître dépositaire du savoir vers le spécialiste de la relation pédagogique, du technicien contrôlé vers un professionnel plus autonome, du concurrent qui sort du lot vers un pair coopératif qui se conforme. Ces déplacements identitaires mettent en relief les manières par lesquelles les interactions au travail ont socialisé les participants à une vision cohérente de l’enseignement dans l’école québécoise par la reproduction des conventions de métier.
La gestion de la sphère travail chez les enseignants du supérieur français. Entre obstacles à surmonter et ressources à capitaliser, quelles stratégies ?
Authors: Paquiot-Papet Jacqueline , Cassignol-Bertrand Florence
Published: July 2021

Le but de cette étude est d’appréhender la gestion de la sphère travail des enseignants-chercheurs (EC) œuvrant dans le système universitaire français. Cette sphère est définie par la combinaison de trois activités, la recherche, l’enseignement, les responsabilités collectives. Partant de l’idée que les ressources de cette sphère sont limitées, en témoigne une charge de travail perçue et reconnue comme importante, le modèle des activités (Curie et Hajjar, 1987, 2000) a été choisi afin d’aborder l’activité réelle (Leplat et Hoc, 1983 ; Yvon et Clot, 2001) des EC sous l’angle des ressources, contraintes et stratégies de régulation choisies pour parvenir à une possible conciliation entre activités. Une enquête qualitative a été menée auprès de 10 EC. Les résultats montrent que des ressources, propices à la conciliation entre activités existent, tout en signalant l’existence de contraintes conditionnant des stratégies de régulation nombreuses.
Adoption of E-Learning During the COVID-19 Pandemic
Authors: Acharjya Biswajit , Das Simanchala
Published: July 2021

The outbreak of the novel coronavirus disease (COVID-19) has resulted in the complete disruption of the learning ecosystem across the world. The sudden shift from the class room learning to the use of virtual platforms has not only made an unprecedented impact on the learning style of the students, but has also resulted in the problem of adoption of the same. Thus, with the significant surge in the usage of e-learning mechanism, the researchers even tend to predict the continued usage of the digital learning platforms post pandemic due to its accelerated usage and adoption by the learners and teachers as well across the age and gender. Therefore, the present research seeks to study the factors influencing e-learning adoption by the students in the context of the pandemic. Further, it would examine the moderating influence of age and gender for the adoption of e-learning using the UTAUT model with extended constructs like computer anxiety, attitude, and technology anxiety.
Factors Influencing Consumer Intention to Subscribe to the Premium Music Streaming Services in China
Authors: Chang Victor , Yang Yifan , Xu Qianwen Ariel , Xiong Chang
Published: July 2021

This study investigates the causes impacting the consumers' intention of the premium music streaming services' subscription in China. An integrated model called the Theory of Streaming Service Acceptance (TSSA) is proposed to explain and predict premium music streaming service subscription behaviors. The TSSA consists of four constructs: attitude, descriptive norm, injunctive norm and perceived behavioral control. The research data was collected in the form of an online survey in China with 120 respondents. Then, interviews were conducted to collect qualitative data from 20 participants. An explanatory sequential mixed method was implemented and the PLS-SEM technique was used to analyze the survey data. The results showed that all constructs in modified research mode, including attitude, injunctive norm and perceived behavioral control except descriptive norm, are indicative predictors for a person’s intention toward premium music streaming services’ subscription. Significant practical inspirations from the perspective of music streaming services providers are also summarized.
Proteolysis-Targeting Chimeras Enhance T Cell Bispecific Antibody-Driven T Cell Activation and Effector Function through Increased MHC Class I Antigen Presentation in Cancer Cells
Authors: Massafra Vittoria , Tundo Sofia , Dietzig Aline , Ducret Axel , Jost Christian , Klein Christian , Kontermann Roland E , Knoetgen Hendrik , Steegmaier Martin , Romagnani Andrea , Nagel Yvonne A
Published: July 2021

The availability of Ags on the surface of tumor cells is crucial for the efficacy of cancer immunotherapeutic approaches using large molecules, such as T cell bispecific Abs (TCBs). Tumor Ags are processed through intracellular proteasomal protein degradation and are displayed as peptides on MHC class I (MHC I). Ag recognition through TCRs on the surface of CD8+ T cells can elicit a tumor-selective immune response. In this article, we show that proteolysis-targeting chimeras (PROTACs) that target bromo- and extraterminal domain proteins increase the abundance of the corresponding target-derived peptide Ags on MHC I in both liquid and solid tumor–derived human cell lines. This increase depends on the engagement of the E3 ligase to bromo- and extraterminal domain protein. Similarly, targeting of a doxycycline-inducible Wilms tumor 1 (WT1)-FKBP12F36V fusion protein, by a mutant-selective FKBP12F36V degrader, increases the presentation of WT1 Ags in human breast cancer cells. T cell–mediated response directed against cancer cells was tested on treatment with a TCR-like TCB, which was able to bridge human T cells to a WT1 peptide displayed on MHC I. FKBP12F36V degrader treatment increased the expression of early and late activation markers (CD69, CD25) in T cells; the secretion of granzyme β, IFN-γ, and TNF-α; and cancer cell killing in a tumor-T cell coculture model. This study supports harnessing targeted protein degradation in tumor cells, for modulation of T cell effector function, by investigating for the first time, to our knowledge, the potential of combining a degrader and a TCB in a cancer immunotherapy setting.
Low-Level Anorectal HIV Shedding despite Effective Antiretroviral Therapy Is Not Driven by Mucosal Inflammation
Authors: Choi Yoojin , Grech Sarah , Mohammadi Avid , Perry Marie-Christine , Huibner Sanja , Sano Marie , Weiss Edward , Coburn Bryan , Salit Irving , Kaul Rupert
Published: July 2021

Although antiretroviral treatment (ART) suppresses HIV RNA in blood and prevents transmission, low-level anorectal HIV RNA shedding persists in some ART-treated men who have sex with men. We collected anorectal biopsies and swabs from 55 men who have sex with men on effective ART, hypothesizing that anorectal shedding would be linked to microbiota-driven mucosal T cell activation. Lymphocytes were assessed by flow cytometry, soluble immune factors by multiplex immunoassay, neutrophils and epithelial integrity by immunofluorescence microscopy, and the anorectal microbiome by quantitative PCR and 16S rRNA gene sequencing. Unexpectedly, we found no evidence that anorectal HIV shedding was associated with the parameters of mucosal inflammation, including T cell activation, inflammatory cytokines, the density of neutrophils, or epithelial integrity. Moreover, the anorectal bacterial load was actually lower in the shedding group, with no major differences in bacterial composition. Instead, the strongest mucosal immune correlates of HIV shedding were an increase in central memory cell frequency and Ki67 expression as well as higher concentrations of the cytokine IL-7 in anorectal secretions. Anorectal HIV RNA shedding during effective ART was not driven by local inflammation; the associations seen with local homeostatic T cell proliferation will require further confirmation.
Characterization of PD-1/PD-L1 immune checkpoint expression in soft tissue sarcomas
Authors: Hashimoto Kazuhiko , Nishimura Shunji , Ito Tomohiko , Akagi Masao
Published: July 2021

Inhibitors of the programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) immune checkpoint system are used for treating various malignancies. However, evidence on their use in soft tissue sarcomas (STS) is limited. This study aimed to retrospectively investigate the relationship between the expression of PD-1/PD-L1 and related antigens in STS, and their association with clinical characteristics. Immunostaining for CD4, CD8, PD-1, PD-L1, IL-2, and IFN-γ was performed using pathological specimens harvested at the time of biopsy from 10 patients with undifferentiated pleomorphic sarcoma (UPS), nine with myxofibrosarcoma (MFS), and three with malignant peripheral nerve sheath tumor (MPNST) who were treated at our hospital. Subsequently, the positive immunostaining cell rates were calculated. We also examined the correlation between each immune positive cell rate and age, tissue grade, size, and maximum standardized uptake (SUV-max) values. The 3-year event-free survival (EFS) and overall survival (OS) rates were compared between the positive and negative groups (positive rate >10%; negative <10%) for various immune stains. The positive rates were also compared between the presence and absence of events groups. There was positive staining for the immune checkpoint molecules in every STS type except for PD-1 in MPNST. CD4, CD8, and PD-1 stained lymphocytes in close proximity to the tumor in adjacent tissue sections. A positive correlation was observed between the positive cell rates of each immune component including inflammatory cytokines such as IL-2 and IFN-γ. Additionally, the clinical features positively correlated with the positive PD-1/PD-L1 expression rates. No significant differences in the 3-EFS and OS rates was observed between the PD-1/PD-L1 positive and negative groups. Our results suggest that an inducible immune checkpoint mechanism may be involved in UPS, MFS, and MPNST.
Matched Unrelated Donor Hematopoietic Stem Cell Transplantation
Authors: Mishra Vikash Chandra , Chandra Dinesh , Dey Nikki , Bhardwaj Amit Kr , Anthwal Archana , Raina Vimarsh
Published: July 2021

Background:

With only 25% chances of finding a human leukocyte antigen matched stem cell donor within the family, in case of minimal residual disease, the dependence on matched unrelated donor (MUD) is inevitable. With increasing awareness about the MUD stem cell registries, the numbers of registrations for voluntary stem cell donations are also increasing each day. A workup coordinator is a strong and the most crucial link in the MUD hematopoietic stem cell transplantation (HSCT) workup. The coordination between the stem cell registry and transplant center TC in need of a MUD HSCT workup is handled by a workup coordinator.

Aims and Objectives:

The aim here is to highlight key roles and responsibilities of workup coordinators, without whom it can be impossible to complete a MUD HSCT.

Materials and Methods:

We accessed the roles and responsibilities of workup coordinators via the MUSD HSCT workup assisted by Genebandhu from May 2012 to August 2020. The methodology mainly involved was electronic communication between stem cell registry/transplant center (TC)/donor center/collection center/patient/donor. All these activities of coordinators were closely observed to understand their roles, requirements, and responsibilities in detail.

Results:

The workup coordinator has been successfully involved in 33 MUD HSCT workups since its inception. Out of these, 18 were from international stem cell registries and 15 with TC s from India.

Discussion:

Workup coordinator acts like a catalyst during a MUD HSCT. Appropriate and timely exchange of information between the registry and the TC is managed by a coordinator.

Conclusion:

This study showed the crucial role, requirements, and responsibilities of the coordinators and their importance in MUD HSCT workups.
Invasive Fungal Diseases in Renal Transplantation - Case Series
Authors: Ganesh Kartik , Abraham M. Abi , Kumar Jithin S. , Simon Sunita
Published: July 2021

We describe 6 cases of invasive fungal diseases in the post kidney transplant setting. These include 2 cases each of mucormycosis and Aspergillosis and 1 case each of pheohyphomycosis and histoplasmosis. Our case series includes the first described case of aspergillus sacroilitis post kidney transplant and also reviews the literature on various modalities of treatment of fungal infections, follow up, diagnostic modalities and appropriate drug choices.
Progressive Familial CD10 Deficient Ductopenic Disorder; Hitherto an Unnamed Entity! - A Case Report
Authors: Bansal Nalini , Rastogi Mukul , Vij Vivek
Published: July 2021

Inherited liver disorders are group of genetic diseases that cause early liver involvement many of them progressing to early cirrhosis. Of the familial cholestatic disorders most widely studied are progressive familial intrahepatic cholestatic disorders. These disorders are caused by defects in enzymes involved with the formation and excretion of bile constituents. They are, however, not associated with ductopenia. We herein report the first case of a familial cholestatic disorder in three female siblings resident of Lahore, Pakistan presenting as chronic cholestasis all progressing to cirrhosis before 10 years of age. The first two female siblings underwent liver transplants for chronic cholestasis. The third sibling underwent liver biopsy for the evaluation of cholestasis and later liver transplant for same. There are no other associated cardiac or skeletal anomalies in any of the sisters. The findings of biopsy and explant tissue were similar in all three sibling sisters. There are features of advanced fibrosis, significant ductopenia, bile ductular reaction at the porto-parenchymal interface, cholestasis, increased copper stores on rhodanine stain no loss of bile salt export pump, and multi-drug resistant 3 protein (MDR3), and the absence of CD10 from canaliculi. The findings raised differentials for progressive familial intrahepatic cholestasis (PFIC) type 3, Alagille syndrome, and variant of familial cholestatic disorder. PFIC 3 causes cholestasis, but the presence of MDR3 stain, ductopenia, and deficient CD10 are not seen in PFIC 3. Familial ductopenic disorders have been identified in the adult population called as idiopathic adulthood ductopenia and had autosomal dominant pattern of inheritance. The argument against Alagille syndrome is the absence of any other syndromic features of Alagille and autosomal recessive mode of inheritance. These findings led us to conclude if there is a need to redefine a new entity of progressive familial CD10 deficient ductopenic disorder. The findings though limited by genetic studies give way for further research on the subject.
A Directed Deceased Donation that Never was - A Case Report
Authors: Seth Avnish Kumar , Singh Twinkle
Published: July 2021

The family of a 48-year-old female with brain death requested for directed donation of a kidney to her brother. Failure to comply with the wishes of the family due to medical reasons resulted in the withdrawal of consent for the donation of all organs. The status of deceased directed donation is discussed and a checklist suggested for the same in India.
Case of Renal Transplant Recipient with Twin Pregnancy - A Case Report
Authors: Srivastava Atul Kumar , Rasheed Md , Ghosh Indranil , Mansingh Sudhir
Published: July 2021

Kidney transplant can restore fertility in young recipients. Preconception counseling should be done for each kidney transplant recipient (KTR) of childbearing age; however, multiple gestations can occur in these patients spontaneously and with assisted reproduction. Pregnancy in KTR can have impact on graft functioning and has obstetrical and fetal implications. We report a 28-year-old KTR with twin pregnancy following intrauterine insemination and challenges associated with it during the pregnancy.
Immunosuppression in Lung Transplantation
Authors: Shah Unmil , Rahulan Vijil , Kumar Pradeep , Dutta Prabhat , Attawar Sandeep
Published: July 2021

Lung transplantation is a definitive treatment option for select end-stage lung disease patients. Post lung transplantation, immunosuppression plays a significant role in a successful outcome. Rejection and infection are commonly encountered where immunosuppression plays an important role. Many immunosuppressive strategies have been designed and their protocols might vary from center to center. This review will focus on these perspectives as well as emerging perspectives during COVID times.