bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of patient decision aid supported shared decision-making intervention in in-person and virtual hybrid pulmonary rehabilitation in older adults with chronic obstructive pulmonary disease: A pilot randomized controlled trial
Authors: Jiang Yuyu , Nuerdawulieti Baiyila , Chen Zhongyi , Guo Jianlan , Sun Pingping , Chen Mengjie , Li Jinping
Published: March 2023

Introduction

Tele-pulmonary rehabilitation is increasingly advocated but cannot completely substitute for in-person services for chronic conditions. Adherence to Pulmonary rehabilitation (PR) remains low in chronic obstructive pulmonary disease (COPD) patients. Shared decision-making (SDM) promotes patients' participation in PR decisions and helps patients and healthcare providers to jointly make decisions that patients are informed and aligned with patient preferences and values, which are critical for patient adherence to PR.

Objective

This study aimed to develop a hybrid in-person and virtual model of home-based PR services for older COPD patients and study the effectiveness of the patient decision aid (PDA)-supported recurring SDM intervention on patient adherence to PR, rehabilitation outcomes, and decision-related outcomes, as well as to explore the mechanisms of the intervention on PR adherence.

Methods

A total of 78 older COPD patients were randomly assigned to the PR group ( n = 39) or PDA-PR group ( n = 39). Both groups were conducted hybrid in-person and virtual PR intervention for 3 months. The primary outcomes were patients’ quality of life and PR adherence. The secondary outcomes were dyspnea symptoms, exercise self-efficacy, knowledge, and decision-related outcomes.

Results

A total of 72 participants completed the 3-month PR program. There were statistically significant differences in PR adherence ( p = 0.033), COPD assessment test (CAT) scores ( p = 0.016), PR knowledge ( p < 0.001), decision self-efficacy ( p < 0.001), decision conflict ( p < 0.001), and decision regret scores ( p = 0.027) between the two groups. The modified Medical Research Council Dyspnoea scale (mMRC) score was significantly decreased only in PDA-PR group ( p = 0.011). No statistically significant differences were observed in St George’s Respiratory Questionnaire (SGRQ) score ( p = 0.078), Exercise Self-Regulatory Efficacy Scale (Ex-SRES) score ( p = 0.29) and COPD knowledge ( p = 0.086) between the two groups. PR value score had a significant effect on adherence to PR ( p = 0.007) and CAT score ( p = 0.028).

Conclusions

PDA supported recurring SDM intervention was helpful in maintaining older COPD patients’ PR adherence and had advantages in improving quality of life, enhancing PR knowledge, decision self-efficacy, and reducing decision conflict and decision regret, but did not improve SGRQ and Ex-SRES. PR value score influenced patients’ rehabilitation adherence and quality of life.

Trial Registration

Chinese Clinical Trial Registry (ChiCTR): ChiCTR1900028563; http://apps.who.int/trialsearch/default.aspx.
Effect of L2 exposure, length of study, and L2 proficiency on EFL learners’ receptive knowledge of form–meaning connection and collocations of high-frequency words
Authors: Lu Cailing , Dang Thi Ngoc Yen
Published: March 2023

High-frequency words are single-words at the first three 1,000-word frequency levels. No studies have explored the impact of current second language (L2) exposure, length of study, and L2 proficiency on the receptive knowledge of high-frequency words of learners of English as a foreign language (EFL) from non-cognate first language (L1) background. To address this gap, this study used the Updated Vocabulary Levels Test and the Receptive Collocation Test to measure the receptive knowledge of form–meaning connection and collocations of high-frequency words of 201 Chinese EFL postgraduate students. It also surveyed these students’ amount of current L2 exposure, length of study, and L2 proficiency. The results showed that, on average, the participants had 20.22 hours of exposure to various types of L2 input per week in and out of class. A series of single linear mixed-effects model analyses revealed that their current L2 exposure and length of study did not seem to have an impact on their knowledge of form–meaning connection of high-frequency words nor their collocational knowledge of these words overall. Yet, L2 proficiency significantly affected their knowledge of form–meaning connection and collocations of the 1st 1,000 words. Knowledge of form–meaning connection also contributed to the collocational knowledge. Pedagogical implications for vocabulary researchers and practitioners were provided.
Influences of home kitchen designs on indoor air quality
Authors: Tsang Tsz Wun , Wong Ling Tim , Mui Kwok Wai , Poon Ching Yi
Published: March 2023

Kitchen indoor air quality (IAQ) has not been well-addressed amongst other IAQ problems at home, despite the fact that cooking is one of the major home activities that can generate high levels of respirable particles and gaseous air pollutants. This study aims at investigating the effects of home kitchen designs on the performance of various ventilation strategies in reducing exposure to IAQ pollutants. The degree of natural ventilation was found to be dependent largely on the relative position of window and door opening, and using mixed ventilation with natural cross-ventilation and mechanical ventilation did not necessarily provide better ventilation. Natural ventilation with the added fume extraction by the exhaust fan could not protect the occupants from high levels of cooking pollutants. Range hood on the other hand could quickly and locally remove particles and gaseous cooking pollutants from the source. The study recommends using a range hood alone during cooking or with single-side natural ventilation to maintain an acceptable IAQ in the home kitchen.
Organizational narratives in rehabilitation-focused dementia care – Negotiating identities, interventions and personhood
Authors: Graff Lea , Timm Helle , Thuesen Jette
Published: March 2023

Background

Rehabilitation is increasingly being introduced in dementia care but studies highlight extensive heterogeneity in practices, conceptual confusion and divergent perceptions of its relevance across care organizations and national contexts. As this have implications for development of dementia care as well as for people with dementia’s access to care it is important to study the organizational narratives and practices in rehabilitation-oriented dementia care organizations.

Methods

The study build on qualitative interviews (individual and group interviews) with health professionals (N = 26) engaged with dementia care and rehabilitation in two Danish municipalities. The interviews were conducted in 2018–2019. The empirical data was analyzed using abductive analysis and theory-based narrative analysis, using Loseke’s conceptualizations of and approach to analyzing formula stories.

Findings

Four dominant organizational narratives were constructed from the data. Each narrative produced a specific organizational narrative of client identity: the active participant in individualized rehabilitation, the inactive individual benefitting from enhanced social environments, the disengaging self and the vulnerable self.

Conclusion

Introducing rehabilitation in dementia care may amplify the organizational polyphonic and provide a plurality of organizational identities each expressing different perceptions of personhood and agency for people with dementia. The organizational narratives were negotiated within a specific structural context where national regulation and dominant discourses on economic challenges and ageing gave precedence to some narratives more than others. In Danish elder care, the first narrative is the most influential but risks excluding people with dementia. Instead, rehabilitation in dementia care is positioned within a social and relational perspective, which may silence important discussion of agency and resistance.
Endovascular Repair of Iatrogenic Inferior Vena Cava and Iliac Vein Injury: A Case Series and Review of the Literature
Authors: Pride Laura , Jackson Kierney , Woody Jonathan , Everett Christopher
Published: March 2023

Objective

Iatrogenic injury to the large abdominopelvic veins can he highly morbid, and open surgical repair is technically challenging. Endovascular repair with covered stenting across the injured segment offers an alternative to open surgical management. We present a series of patients with operative injury to the inferior vena cava (IVC) and iliac veins who were treated utilizing an endovascular approach and review the available literature on this technique.

Methods

A PubMed keyword and MeSH term search was performed, and titles were reviewed for relevance by the first author. Studies related to endovascular repair of iatrogenic injury to the IVC and iliac veins were then read in detail for possible inclusion in the review. Those deemed appropriate were further analyzed for interventional approach, stent type and size, technical success, post-procedural pharmacologic management, complications and surveillance strategy.

Results

The initial search resulted in 6221 publications. A total of 17 met criteria for inclusion, all of which were case reports or series. Twenty-six patients were described as suffering iatrogenic injury to the IVC or iliac veins, treated with various types and sizes of stents. All cases achieved technical success with hemorrhage control. Procedural complications occurred in 15.4% of cases, including 3 cases of acute thrombus formation and 1 case of stenosis caudal to the initial stent edge requiring additional stenting. Two additional patients experienced stent occlusion in the surveillance period.

Conclusions

Endovascular repair of iatrogenic injury to the IVC and iliac veins can be an effective management option. However, due to limited data regarding this approach, many technical questions remain, including ideal size and type of stent graft, necessity and duration of post-procedural anticoagulant or antiplatelet therapy and appropriate surveillance. Additionally, long term outcomes in this population have not yet been described.
IVUS Identification of Undiagnosed Popliteal Aneurysm in the Setting of Acute Limb Ischemia
Authors: Moore Cameron , Williamson Kayla , Ghani Muhammad Owais Abdul , Nathoo Tayla , O’Keeffe Shane , Danapal Magendran
Published: March 2023

Intravascular ultrasound (IVUS) is a catheter-based procedure that allows for the internal assessment of a blood vessel. This includes evaluation of diameter, stenosis, calcification, and dissection. We present a case in which IVUS led to the discovery of a popliteal artery aneurysm in the setting of acute limb ischemia that was missed on computed tomography scan and angiogram.
Per- and Polyfluoroalkyl Substances and Outcomes Related to Metabolic Syndrome: A Review of the Literature and Current Recommendations for Clinicians
Authors: Hall Amber M. , Braun Joseph M.
Published: March 2023

Per- and polyfluoroalkyl substances (PFAS) are a class of toxic, ubiquitous, anthropogenic chemicals known to bioaccumulate in humans. Substantial concern exists regarding the human health effects of PFAS, particularly metabolic syndrome (MetS), a precursor to cardiovascular disease, the leading cause of mortality worldwide. This narrative review provides an overview of the PFAS literature on 4 specific components of MetS: insulin resistance/glucose dysregulation, central adiposity, dyslipidemia, and blood pressure. We focus on prospective cohort studies as these provide the best body of evidence compared to other study designs. Available evidence suggests potential associations between some PFAS and type-2 diabetes in adults, dyslipidemia in children and adults, and blood pressure in adults. Additionally, some studies found that sex and physical activity may modify these relationships. Future studies should consider modification by sex and lifestyle factors (e.g., diet and physical activity), as well quantifying the impact of PFAS mixtures on MetS features and related clinical disease. Finally, clinicians can follow recently developed clinical guidance to screen for PFAS exposure in patients, measure PFAS levels, conduct additional clinical care based on PFAS levels, and advise on PFAS exposure reduction.
Multi-objective optimization design in a centrifugal pump volute based on an RBF neural network and genetic algorithm
Authors: Guo Rong , Li Xiaobing , Li Rennian
Published: March 2023

The hydraulic and acoustic performance of centrifugal pumps are interrelated and contradictory in hydraulic structure design. An optimization design method of a volute based on a radial basis function (RBF) neural network and genetic algorithm (GA) is proposed to solve this problem. The efficiency and total sound pressure level of the centrifugal pump are used as the optimization objectives. The diameter of the base circle, the width of the base circle, the installation angle of the volute tongue, and the height of the volute diffuser tube are used as the optimization variables. Latin hypercube sampling (LHS) is used to establish the sample space, the RBF neural network is used to build the agent model between the optimization variables and objectives, and the GA is used to multi-objective optimization. For the Pareto solution set obtained, two extremal individuals and initial individuals are selected for comparative analysis of hydraulic and acoustic performance under different working conditions. The result demonstrates that under the rated working condition, compared with the initial individual, the efficiency of the optimal individual of efficiency increases by 3.79%; the internal noise of the optimal individual of sound pressure level decreases by 5.5%, and the external noise decreases by 2.3%.
An integrative literature review of substance use treatment service need and provision to pregnant and postpartum populations in carceral settings
Authors: Steely Smith Mollee K , Wilson Stephanie H , Zielinski Melissa J
Published: March 2023

Pregnancy is a critical time to provide access to substance use treatment; this is especially true among incarcerated populations, who are known to be at particularly high risk of poor health outcomes. In this integrated literature review, we (1) report what is known about the prevalence of substance use among incarcerated pregnant and postpartum populations; (2) describe substance use treatment programs and current care practices of pregnant and postpartum populations in carceral settings; and (3) explore recommendations and strategies for increasing access to substance use treatment for incarcerated pregnant and postpartum populations. A comprehensive search of seven electronic databases yielded in the retrieval of 139 articles that were assessed for inclusion. Of the retrieved articles, 33 articles met criteria for inclusion in this review. A review of the literature revealed that the understanding of substance use prevalence among pregnant incarcerated women is limited. We also found that treatment of substance use disorders among pregnant and postpartum populations is not routinely available, enhanced perinatal services are sorely needed, and substance use treatment programs are feasible with the help of community partnerships. More research is required to understand current substance use treatment initiatives and outcomes for pregnant women in prison. In addition, strategies for integrating evidence-based, substance use treatment in carceral settings is also needed. Future directions are discussed.
Optimal block replacement based on expert judgement method
Authors: Dehsoukhteh Somayyeh Shahraki , Razmkhah Mostafa , Castanier Bruno
Published: March 2023

Applying the theory of uncertainty is a good approach to study the reliability of a system when there is a little frequency of suitable data. Based on this theory, the policy of block replacement with minimal repair is considered assuming the system lifetime follows a power law process. The unknown parameters are estimated according to evidence theory that affects the epistemic uncertainty. The Dempster-Shafer as well as Yager rules are applied to aggregate the judgements and mental estimates of two or more experts. After determining the unknown parameters, a judgement interval is derived for the optimal replacement time using the long-run cost criterion.
No Room of Her Own: The Erotics of the Nineteenth-Century Actress's Dressing-Room
Authors: Senelick Laurence
Published: March 2023

Although their backstage activities had been a source of titillation from the time women first appeared on the public stage (see Hogarth's Strolling Actresses Dressing in a Barn), in the nineteenth century actress's dressing-rooms became a distinct site of libidinous fantasy. In the major European and American playhouses, star dressing-rooms were suites that approximated the rococo boudoir. This study explores how the dressing-room became a fixture in the erotic mentalité of the period, and, in the process, crystallised the image of the actress as sequestered divinity engaged in mysterious rites of glamour, camouflaging the corruption beneath. The chief examples are Édouard Morin's paintings of Hortense Schneider, Zola's novel Nana, and both the play and opera Zaza, with a note on Colette's female gaze at the subject.
OXTR polymorphisms and parental bonding modulate alexithymia: The main effects and interaction
Authors: Zhao Wenping , Yang Yuting , Guo Wenxuan , Gong Pingyuan
Published: March 2023

Alexithymia is a subclinical personality disorder characterized by difficulties in identifying and expressing one's own emotion. Individual differences in alexithymia are influenced by both genetic and environmental factors. However, the interplay between these factors and their influences on alexithymia are unclear. Considering that oxytocin plays important roles in emotion processing and that parental bonding influences the development of alexithymia, we explored the associations between OXTR polymorphisms and alexithymia and examined whether the potential associations are moderated by parental bonding. To this end, we genotyped the OXTR polymorphisms (rs53576 and rs1042778) and scored alexithymia and parental bonding with the Toronto Alexithymia Scale and the Parental Bonding Instrument. Results indicated that: (1) the characteristics of alexithymia were negatively associated with parental care and positively with parental overprotection; (2) the OXTR rs53576 was significantly associated with the characteristics of alexithymia, such that the AA genotype was associated with fewer difficulties in identifying feelings and describing feelings than the AG/GG genotypes; and (3) the OXTR rs1042778 interacted with parental care in alexithymia with the vantage sensitivity model: the GG genotype was related to less severity of alexithymia than the AG/GG genotypes only in individuals with higher parental care. Overall, these findings suggest that the OXTR is related to alexithymia and that the quality of parental care influences the relationship. However, considering that the evidence from this study is weak, more research is needed to understand the roles of OXTR in alexithymia.
Comparing the ideological correlates of anti-government and anti-Roma conspiracy beliefs in Romania
Authors: Nera Kenzo , Procop Iustina , Klein Olivier
Published: March 2023

Conspiracy theories are often viewed as the manifestation of a “conspiracy mentality” grounded in power-challenging attitudes. Contrary to this approach, it has been proposed that conspiracy theories targeting relatively powerful groups (i.e., upward conspiracy theories) may be ideologically distinct from conspiracy theories targeting relatively powerless groups (i.e., downward conspiracy theories). We tested this contention in the Romanian context ( n = 723, preregistered) and compared the ideological and socioeconomic correlates of anti-government (i.e., a relatively powerful group) and anti-Roma (i.e., a relatively powerless group) conspiracy beliefs. Using Principal Components Analysis, we showed that both categories of conspiracy beliefs are statistically distinct. Right-wing authoritarianism was significantly more related to anti-Roma conspiracy beliefs than to anti-government conspiracy beliefs. However, against our expectations, both types of conspiracy beliefs did not relate differently to subjective socioeconomic status. Overall, the ideological discrepancies between upward and downward conspiracy beliefs were less marked in the Romanian context. Finally, conspiracy mentality was more related to anti-government conspiracy beliefs than anti-Roma conspiracy beliefs. This corroborates the notion that generic measurements of conspiracist ideation may be mostly a measurement of upward conspiracy beliefs, and emphasizes the relevance of distinguishing conspiracy theories based on the types of groups they target.
All Children Deserve to Be Safe, Mothers Too: Evidence and Rationale Supporting Continuous Glucose Monitoring Use in Gestational Diabetes Within the Medicaid Population
Authors: Levy Carol J. , Galindo Rodolfo J. , Parkin Christopher G. , Gillis Jacob , Argento Nicholas B.
Published: March 2023

Gestational diabetes mellitus (GDM) is a common metabolic disease of pregnancy that threatens the health of several million women and their offspring. The highest prevalence of GDM is seen in women of low socioeconomic status. Women with GDM are at increased risk of adverse maternal outcomes, including increased rates of Cesarean section delivery, preeclampsia, perineal tears, and postpartum hemorrhage. However, of even greater concern is the increased risk to the fetus and long-term health of the child due to elevated glycemia during pregnancy. Although the use of continuous glucose monitoring (CGM) has been shown to reduce the incidence of maternal and fetal complications in pregnant women with type 1 diabetes and type 2 diabetes, most state Medicaid programs do not cover CGM for women with GDM. This article reviews current statistics relevant to the incidence and costs of GDM among Medicaid beneficiaries, summarizes key findings from pregnancy studies using CGM, and presents a rationale for expanding and standardizing CGM coverage for GDM within state Medicaid populations.
A review of the factors influencing adoption of digital health applications for people living with dementia
Authors: Conway Aoife , Ryan Assumpta , Harkin Deirdre , Mc Cauley Claire , Goode Deborah
Published: March 2023

Objective

Researchers have used various theories and models to understand technology adoption, however, with the growing interest and availability of mobile applications (apps) for people living with dementia, it is desirable to have a broader insight into how technology adoption may be further improved. This paper aims to explore the factors influencing the adoption of digital health applications for people living with dementia and add to the current literature on this topic.

Methods

Searches were conducted in CINHAL, Web of Science, Psych Info, ProQuest Health and Medical, IEEE Xplore and Scopus. Citation searching and handsearching were used in the identification of other studies.

Results

Following an assessment of relevancy, nine studies remained and are included within this review. Methodological quality was assessed using The Mixed Methods Appraisal Tool (MMAT). A thematic analysis was used for the data synthesis of included studies. Each study reported on different types of apps.

Conclusion

From the synthesis of included studies, four analytic themes were identified; Theme 1: Personal and contextual factors; Theme 2: Perceived value and benefit; Theme 3: Design and content of app; and Theme 4: Digital Literacy and Confidence. People are diverse and so are their reasons for the adoption of apps. These findings provide an insight into the range of factors that impact the adoption of apps for people living with dementia. Understanding the factors that impact the adoption of mobile applications is critical to their success. These findings can be beneficial for app developers and for people living with dementia and their carers.
Causal effects of physical activity on the risk of overall ovarian cancer: A Mendelian randomization study
Authors: Wang Jing , Zhao Huanling , Zhu Jiahao , Jiang Minmin
Published: March 2023

Objective

Inconsistent results were reported on the association of physical activity with ovarian cancer. However, given the limitations of confounders and inverse causation, the validity of the association remained unclear. Therefore, we conducted a two-sample Mendelian randomization analysis, which can effectively avoid the aforementioned interference, to evaluate whether physical activity had a protective effect on ovarian cancer.

Methods

The exposure of interest was physical activity (both self-reported moderate-to-vigorous physical activity and accelerometer-measured physical activity). Summary statistics for physical activity traits were recruited from the UK Biobank ( n  =  91,084–377,234), whereas ovarian cancer summary genetic data were obtained from a genome-wide association study involving 25,509 cases and 40,941 healthy individuals. The inverse variance weighted approach was used as the primary Mendelian randomization method. Sensitivity analyses using Mendelian randomization-Egger regression, weighted median, and Mendelian randomization pleiotropy residual sum and outlier were also performed.

Results

The Mendelian randomization analyses indicated that there was no effect of moderate-to-vigorous physical activity (odds ratio, 1.11; 95% confidence interval: 0.66–1.85; P   =  0.702), accelerometer-measured “average acceleration” (0.99 [0.91–1.08]; P   =  0.848), and “overall activity” physical activity (0.97 [ 0.48–1.95]; P   =  0.927) on the risk of overall ovarian cancer. However, “overall accelerations” physical activity (0.18 [0.05–0.64]; P   =  0.008) were suggestively related to a lower risk of endometrioid ovarian cancer.

Conclusions

The Mendelian randomization analyses suggested that physical activity may not help to decrease the risk of overall ovarian cancer.
Disease associations of excessive daytime sleepiness in multiple sclerosis: A prospective study
Authors: Sguigna Peter V , Toranian Sabeen , Tardo Lauren M , Blackburn Kyle M , Horton Lindsay A , Conger Darrel , Meltzer Ethan , Hogan R Nick , McCreary Morgan C , Zee Phyllis C , Takahashi Joseph S , Greenberg Benjamin M
Published: March 2023

Background

Excessive daytime sleepiness (EDS) in multiple sclerosis (MS) can be a significant source of disability. Despite this, its prevalence as a patient-reported outcome in this condition has not been well established, and its causes are not well understood.

Methods

We prospectively assessed EDS as part of an observational study for patients referred for diagnostic neuro-ophthalmological testing. EDS was evaluated by the Epworth Sleepiness Scale (ESS), and visual data were also collected as part of a research protocol. Analysis with patient data was performed following the exclusion of patients with known primary sleep disorders.

Results

A total of 69 patients with MS were included in the analysis. The mean ESS was 6.5 with a SD of 4.3. ESS ≥ 10 was present in 23% of the cohort even in the presence of minimal mean neurological disability (Patient Determined Disease Steps (PDDS) = 1.5). The ESS score was not associated with age, sex, disease-related disability, retinal nerve fiber layer (RNFL), or optic neuritis (ON), but displayed an association with visual dysfunction.

Conclusions

There is an increased prevalence of EDS in MS. The increased values of the ESS are not explained by other sleep disorders, suggesting separate mechanisms. Further study of the underlying mechanisms is warranted.
“It was Hard to Prepare without Knowing What I was Preparing for”: Latine Youth Experiences of a First-Generation College-Going Group
Authors: Havlik Stacey , Malott Krista , Wheatcroft Jaime , Salas Sylvia
Published: March 2023

This article describes the experience of participants and facilitators engaging in a psychoeducational group counseling intervention designed to enhance college readiness among Latine first-generation college-going students—those for whom neither parent completed college (National Center for Education Statistics, 2017). The group was designed to increase students’ understanding of how their various identities impacted their college preparatory experience and willingness to seek help. Findings suggest that participants recognized the importance of their identities and the way they influenced their help-seeking behaviors. Participants identified similarities among their experiences related to college going while also valuing learning from each other’s differences. Last, participants felt a sense of uncertainty and angst about going to college. We also share facilitator experiences.
Adapted Strong Kids Curriculum for English Language Learners During COVID-19
Authors: Shi Qi , Phillips Karen , Moody Desvan , Cordova Thania
Published: March 2023

This study describes and provides preliminary support for the use of a culturally and linguistically adapted Strong Kids curriculum, delivered completely online, to address English language learners’ (ELLs’) social/emotional development. Quantitative data showed an increase in students’ social/emotional knowledge in internalizing symptoms by the end of the program. Qualitative data highlighted ELL students’ increased ability to identify and manage emotions, their application of social/emotional learning and mindfulness concepts in the virtual classroom, and the benefits of participating in the program virtually. We discuss the findings and implications for school counselors and other mental health providers in both school and community settings.
Factors Related to Accessing Postsecondary School Supports by English Learners With Disabilities
Authors: Newman Lynn A. , Trainor Audrey A. , Romano Lindsay
Published: March 2023

This study examined the relationship between demographic, disability-related, and transition planning experiences and accessing disability-specific and universally available supports at 2- and 4-year colleges by postsecondary students identified in secondary school as English learners with disabilities. Findings were based on secondary analysis of a nationally representative sample of approximately 160 English learners with disabilities included in the National Longitudinal Transition Study-2 (NLTS2). Logistic regression results identified two potentially malleable factors linked to increased likelihood of English learners with disabilities accessing postsecondary supports. If these students had a high school transition plan that indicated postsecondary supports as a needed post-high school service, when they attended college they were more likely to access both postsecondary disability-specific supports ( p < .01), and supports universally available to the full postsecondary student body ( p < .001). Aspects of self-determination also were related to an increased likelihood of seeking postsecondary supports. Higher levels of personal autonomy were positively related to accessing disability-specific ( p < .001) and universally available help ( p < .05), and higher levels of psychological empowerment were related to receipt of universally available supports ( p < .01). These findings demonstrate that high school professionals can support the postschool success of English learners with disabilities by influencing their likelihood of accessing beneficial supports in postsecondary school.
Hearing Thresholds for Unscreened U.S. Adults: Data From the National Health and Nutrition Examination Survey, 2011–2012, 2015–2016, and 2017–2020
Authors: Humes Larry E.
Published: March 2023

Hearing threshold levels (HTLs) at 500–8,000 Hz from the National Health and Nutrition Examination Survey (NHANES) 2011–2012, 2015–2016, and 2017–2020 were analyzed for males and females ranging in age from 20 to 80-plus years ( N = 8,795). HTLs for the 10th, 25th, 50th, 75th, and 90th percentiles are provided for males and females. Equations were generated to describe median HTLs as a function of age at each frequency. The medians generated for this unscreened dataset of U.S. adults were compared to those in Table B.3 of ISO 1999 (2013), which came from analyses of the NHANES 1999–2006 datasets. The ISO 1999 values were found to be slightly higher (worse) at several frequencies. The ISO 1999 (2013) median HTLs were 2 to 5 dB worse at 500 Hz for males and females and 2 to 8 dB worse at 4,000 and 6,000 Hz for males than the updated NHANES estimates. As in prior analyses of NHANES data, HTLs worsened with age, were better for females than males, and were better for Non-Hispanic Blacks than for Non-Hispanic Whites. The latter difference was observed for both males and females, was confined to frequencies above 2,000 Hz, and widened with increasing age.
Family-Based Psychosocial Interventions for Severe Mental Illness: Social Barriers and Policy Implications
Authors: Kuhney Franchesca S. , Miklowitz David J. , Schiffman Jason , Mittal Vijay A.
Published: March 2023

Severe mental illnesses (SMI) such as schizophrenia, major depressive disorder, and bipolar disorder are prevalent, debilitating, and chronic conditions that come with significant costs to families, public health systems, and communities. Research indicates that emotional qualities within the family environment of the person with SMI (e.g., whether members are highly supportive, critical, or emotionally overinvolved) can either protect against or increase the risk for psychiatric relapse. Dovetailing this work is research indicating that family-based psychosocial interventions, which can increase family functioning through psychoeducation and skill building, can promote positive outcomes for individuals with SMI. Unfortunately, social barriers such as financial strain, inaccessibility of specialized care, stigma, and social marginalization may impede a patient's or family's ability to initiate and/or continue family services. We propose that improving treatment engagement requires a combination of state and federal policy initiatives supporting community resources, integrated health care, and partnerships with national organizations.
How Can We Move Advanced Methodology into Practice More Effectively?
Authors: Pek Jolynn , Bauer Daniel J.
Published: March 2023

Methodology serves an essential role in advancing psychological science. However, meta-science research points to a leaky translational pipeline in which substantive research often fails to utilize recommended methodological practices. Various explanations for this problem include valuing the development of methods over methodology (making tools over using tools), incentives for methodological research, incentives for promoting pedagogy in methodology, an insufficient number of quantitative methodologists in the discipline, and scarcity of resources for substantive researchers seeking more advanced methodological training. Policy makers might consider several recommendations that could mitigate extant leaks in the translational pipeline.
Biofeedback Has Therapeutic Effects on Asthma, Although Additional Research Is Needed to Document Specificity
Authors: Lehrer Paul , Moritz Gali
Published: March 2023

Asthma is a common disorder leading to significant disability and healthcare cost throughout the world. Although medical treatment is usually highly effective in controlling it, asthma medicines often have high costs and attendant side effects. Biofeedback is an inexpensive noninvasive alternative with minimal side effects. This paper reviews evidence for two validated biofeedback treatments for treating asthma, heart rate variability biofeedback (HRVB), and muscle relaxation with surface electromyographic biofeedback. In multiple studies, although most of them are of modest size, both methods have clinically meaningful results, often allowing decreases in the use of steroid medication. Further research is needed to prove which specific components of HRVB are responsible for clinical effects, and to determine asthma populations that can best benefit from these methods. Despite demonstrated effectiveness, few insurance schemes reimburse for biofeedback, and national guidelines consider it only as worthy of further investigation. Funding for the requisite large-scale clinical trials remains lacking, creating a limbo-like status quo for these useful methods.
The benefits of a cyber-resilience posture on negative public reaction following data theft
Authors: Toma Traian , Décary-Hétu David , Dupont Benoît
Published: March 2023

Research shows that customers are insufficiently motivated to protect themselves from crimes that may derive from data theft within an organisation. Instead, the burden of security is placed upon the businesses that host their personal information. Companies that fail to sufficiently secure their customers’ information thus risk experiencing potentially ruinous reputational harm. There is a relative dearth of research examining why some businesses that have been breached stay resilient in the face of negative public reaction while others do not. To bridge this knowledge gap, this study tackles the concept of cyber-resilience, defined as the ability to limit, endure, and eventually bounce back from the impact of a cyber incident. A vignette-based experimental study was conducted and featured: (1) a breached business described as having a strong cyber-resilience posture; (2) a breached business described as having a weak cyber-resilience posture. Overall, a convenience sample of 605 students in Canada were randomly assigned to one of the two main experimental conditions. The results show that a strong cyber-resilience posture reduces negative customer attitudes and promotes positive customer behavioral intentions, in comparison to a weak cyber-resilience posture. Similarly, the more negative attitudes a customer holds toward a breached business, the less likely they are to behave favorably toward it. As a result of this study, cyber-resilience, which has hitherto primarily received conceptual attention, gains explanatory power. Furthermore, this research project contributes more generally to business victimology, which is an underdeveloped field of criminology.
Developing a Tool for Measuring Parent Knowledge and Barriers to Supportive School Integration After Diagnosis of Childhood Cancer
Authors: Parrillo Elaina , Perrin Nancy , Ruble Kathy , Paré-Blagoev E. Juliana , Jacobson Lisa A.
Published: March 2023

Background: Children treated for cancer are at risk for long-term neurocognitive late effects that can impact school attainment, employment, and quality of life. Obtaining formal education support can be critical to later success but may depend upon parent knowledge and ability to access needed support. The purpose of this study was to develop and evaluate the psychometric properties of a scale to measure the perceived support that parents received upon their child's return to school during or after cancer treatment. Methods: Exploratory factor analyses evaluated the construct validity of survey items. Cronbach's alpha was used to test the internal consistency and independent t-tests evaluated the concurrent criterion validity of resulting subscales. Results: The exploratory factor analyses resulted in two subscales, Barriers to Supportive School Integration (13 items) and Parent School Integration Knowledge (three items). All items loaded at least 0.49 onto each factor, with Cronbach's alpha values of 0.927 and 0.738, respectively. The Knowledge subscale additionally demonstrated concurrent criterion validity; higher Knowledge subscale scores were found among parents who reported receiving information about treatment-related cognitive/school problems from healthcare providers ( p < .001). Discussion: The Parent School Integration Knowledge and Barriers to Supportive School Integration subscales demonstrated preliminary evidence for good construct validity and internal consistency. These subscales may be used in future research to assess parent knowledge, barriers to receiving support, and overall experience of supportive school integration after the diagnosis of pediatric cancer.
Insomnia in primary care: Considerations for screening, assessment, and management
Authors: Yamamoto Mari , Lim Christopher T , Huang Heather , Spottswood Margaret , Huang Hsiang
Published: March 2023

Insomnia, including insomnia disorder, is a common but often overlooked complaint in primary care settings. It is a risk factor for various medical and psychiatric diagnoses and is associated with substantial health care costs. While cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment for insomnia disorder, access to CBT-I is limited. This article provides a pragmatic approach to screening, assessment, and treatment of insomnia in the primary care setting, promoting a population health approach. The authors review the role of CBT-I, treatment of comorbid conditions, and pharmacologic recommendations in working with primary care patients with insomnia. In addition, the authors highlight the potential utility of technology in improving access to insomnia care.
Tumor-expressed factor VII is associated with survival and regulates tumor progression in breast cancer
Authors: Kroone Chantal , Tieken Chris , Kocatürk Begüm , Paauwe Madelon , Blok Erik J. , Ünlü Betül , van den Berg Yascha W. , Stanganello Eliana , Kapteijn Maaike Y. , Swier Nathalie , Zhang Xi , Duits Danique E. M. , Lin Yazhi , Oostenbrink Lisa V. E. , van den Akker Rob F. P. , Mosnier Laurent O. , Hawinkels Lukas J. , van Vlijmen Bart J. M. , Ruf Wolfram , Kuppen Peter J. , Cannegieter Suzanne C. , Buijs Jeroen T. , Versteeg Henri H.
Published: March 2023

Cancer enhances the risk of venous thromboembolism, but a hypercoagulant microenvironment also promotes cancer progression. Although anticoagulants have been suggested as a potential anticancer treatment, clinical studies on the effect of such modalities on cancer progression have not yet been successful for unknown reasons. In normal physiology, complex formation between the subendothelial-expressed tissue factor (TF) and the blood-borne liver-derived factor VII (FVII) results in induction of the extrinsic coagulation cascade and intracellular signaling via protease-activated receptors (PARs). In cancer, TF is overexpressed and linked to poor prognosis. Here, we report that increased levels of FVII are also observed in breast cancer specimens and are associated with tumor progression and metastasis to the liver. In breast cancer cell lines, tumor-expressed FVII drives changes reminiscent of epithelial-to-mesenchymal transition (EMT), tumor cell invasion, and expression of the prometastatic genes, SNAI2 and SOX9. In vivo, tumor-expressed FVII enhanced tumor growth and liver metastasis. Surprisingly, liver-derived FVII appeared to inhibit metastasis. Finally, tumor-expressed FVII-induced prometastatic gene expression independent of TF but required a functional endothelial protein C receptor, whereas recombinant activated FVII acting via the canonical TF:PAR2 pathway inhibited prometastatic gene expression. Here, we propose that tumor-expressed FVII and liver-derived FVII have opposing effects on EMT and metastasis.
A multi-aspect analysis of two analogous aspergillus spp. belonging to section Flavi: aspergillus flavus and aspergillus oryzae
Authors: Suleiman Waleed Bakry
Published: March 2023

Microfungal isolates were routinely identified depending on both macro and micro morphological characteristics, sometimes, some fungal isolates appeared to be similar and such cases caused severe confusion for mycologists during the preliminary identification. During our previous studies dealing with isolation of fungi for some biotechnological applications; two mystifying species Aspergillus flavus and Aspergillus oryzae showed similar cultural and macroscopic features. Therefore, the current study aimed to easily distinguish between these two species depending on simple approaches which are routinely followed by a large segment of researchers. Investigation of the macroscopic features was performed to check the fungal growth on four different media (PDA, MEA, YES, and CYA) followed by microscopic examination using an ordinary light microscope, and scanning electron microscope SEM. Also, screening of secondary metabolites for both strains was preliminarily identified to find out the difference between their metabolic profiles. Finally, ITS rDNA was involved to clarify the molecular differences along their partial sequence. Conclusively, the BLAST strategy confirmed the similarity of ITS rDNA segments of both fungal strains that supported our hypothesis. The color of the fungal growth is a very critical factor whereas it is extensively influenced by the type of cultivation media. Accordingly, the YES medium was an inspiring tool assisting in prompt differentiation during the culture investigation step whereas A. oryzae and A. flavus appeared significant mustard yellow and olive green respectively. During the microscopic examination, the CYA medium also had a robust effect on the formation of the conidial chain whereas the knit long chain was observed in A. oryzae while the conidia appeared scattered and not in a chain in the case of A. flavus. Likewise, both two strains possessed different metabolic profiles where A. oryzae is not an Afla toxin producer, unlike A. flavus.
Pathological and clinical characteristics of late-onset oligomeganephronia based on a histomorphometric study
Authors: Ren Ya-Li , Li Yang , Gao Jie , Zhou Xu-Jie , Yang Li , Wang Su-Xia
Published: March 2023

Background

Late-onset oligomeganephronia (OMN) is a rare chronic kidney disease and has no quantitative criteria for diagnosis yet. The current study aimed to explore its clinicopathological features by histomorphometric analysis.

Methods

We retrospectively re-reviewed all patients with enlarged and sparse glomeruli by light microscopy at Peking University First Hospital from 2012 to 2021, excluding those with any factor known to contribute to similar changes. Age- and sex-matched patients with thin basement membrane nephropathy were selected as control to establish the cut-off values for glomerulomegaly and rarity. Late-onset OMN cases were then confirmed and the clinicopathological characteristics were summarized.

Results

Mean diameter and density of cortical glomeruli in control was 156.53 ± 27.50 μm and 4.07 ± 0.63 /mm2, giving a lower limit of 211.53 μm for glomerulomegaly and an upper of 2.81 /mm2 for rarity. Seven adults of three females and four males were finally diagnosed as late-onset OMN with a mean age of 26.57 years. They showed mild to moderate proteinuria and/or renal dysfunction at biopsy with the mean proteinuria, serum creatinine (Scr) level, and estimated glomerular filtration rate of 0.50 g/d (0.10–0.95 g/d), 140.9 µmol/L (95.1–227.1 µmol/L), and 58.7 mL/min/1.73m2 (21.3–98.0 mL/min/1.73m2), respectively. Four patients (57.1%) had normal Scr at diagnosis. Six patients with available data showed renal tubular injury with increased urinary microalbumin in all, elevated N-acetyl-β-glucosaminidase in two, and elevated α1 microglobulin in five. Kidney size was normal or slightly reduced. The mean density and glomerular diameter of the seven cases was 0.86 mm2 (0.55–1.41 /mm2) and 229.73 μm (211.88–260.66 μm). Segmental glomerular sclerosis was observed in six (85.7%) with four (66.7%) of perihilar type. Proximal tubule dilation was observed in all, focal to diffuse, lining with enlarged epithelial cells. The mean foot process width was 634.02 nm, wider than 472.54 nm of the control (P = 0.0002).

Conclusion

Late-onset OMN should be considered a special entity with relatively slow clinical progress characterized by hypertrophy of the sparsely distributed nephron.