bluuebunny/crossref_metadata_2025 huggingface dataset:
Сюжетно-композиційна (не-)конвенційність творчості Олеся Ульяненка
Authors: Shteinbuk Feliks
Published: January 2022

The article examines the features of the plot-composition structure of every finished novel by the modern Ukrainian writer Oles Ulianenko, including Stalinka and Perly i svyni (The pearls and the pigs), having researched how standard elements, such as exposition, conflict, rising action, climax and resolution, are realized conventionally and non-conventionally in these literary works. The research results are as follows: the linear and sequential variant of the plot-composition structure of Oles Ulianenko’s novels is broken not because of the dynamics determined by the outer factors but due to the atypical plots. Besides, these structures are characterized by the socially oriented author’s discourse. However, the social array of the novels is united with the corporal background of the social and personal existence of the characters in the works under analysis, and with intentions to comprehend ontological senses which are formed on the border of the controversial phenomena, social and corporal existence in particular.
Сучасна українська література в об’єктиві студій пам’яті: жіночі виміри
Authors: Pukhonska Oksana
Published: January 2022

The article is dedicated to a very important topic, which belongs not only to literature but also to Ukrainian history, culture and social life. Speaking about memory, we mean the experience of the past, which very often influences the main aspects of our modernity, in particular, if we are talking about traumatic experience of the history, which was not rethought and did not become a socio-cultural discourse. In the context of the mentioned research problem, the fact that women experience cruelty, humiliation, and injustice is one of those questions, which were not solved during the last decades of developing of democratic societies. Contemporary Ukrainian literature tries to find a solution of unfair reception of the past using a very important method of rethinking traumatic memory. That is why it becomes the subject of different researches, one of which is in the suggested article.
DIAMANTES EM DEPÓSITOS COLUVIONARES DO TAPAJÓS (ITAITUBA, PARÁ)
Authors:   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil, Brito Marcus , Costa Marcondes ,   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil, Pöllmann Herbert ,   Martin-Luther Universität Halle-Wittenberg, Institut für Geologische Wissenschaften, Halle an der Saale, Germany, Chaves Mário ,   Instituto de Geociências da Universidade Federal de Minerais, Belo Horizonte, Minas Gerais, Brasil, Hohn Helmut ,   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil
Published: January 2022

The diamonds from the Painin garimpo, on the Tapajós River, in Itaituba, state of Pará, were mined in alluvial gravel in geological terrains dominated by the Barreirinha, Itaituba and Monte Alegre Paleozoic formations. 30 diamonds extracted from the concentrates of this garimpo were analyzed by stereomicroscopy, optical microscopy, x-ray diffraction, scanning electron microscopy with EDS and luminescence. The average weight of these specimens is 0.42 ct and the predominant forms are dodecahedral and octahedral, in addition to others such as ballas and bort. Surface figures, microstructures, luminescence, and various inclusions are recognized. The inclusions can be classified as syngenetic (periclase, diopside, among others) and epigenetic (eg minerals of crandallite group). Green covers were also observed. This study, however, was not able to solve the problem of the genesis of the diamond in the studied region, as happens to date with most secondary diamond deposits in the Amazon region (Tapajós, Tocantins and Tepequém-Maú), except for those related to kimberlite pipes of Mato Grosso Rondônia.
SEIXOS DE FOSFATOS-SULFATOS DOS MINERAIS DO SUPERGRUPO ALUNITA NOS ALUVIÕES DIAMANTÍFEROS DE PAININN ÀS MARGENS DO TAPAJÓS EM ITAITUBA (PARÁ): GOYAZITA-FLORENCITA-GORCEIXITA-CRANDALLITA-ESVANBERGITA/WOODHOUSEITA
Authors:   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil, Costa Marcondes , Brito Marcus ,   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil, Chaves Mário ,   Instituto de Geociências da Universidade Federal de Minerais, Belo Horizonte, Minas Gerais, Brasil, Pöllmann Herbert ,   Martin-Luther Universität Halle-Wittenberg, Institut für Geologische Wissenschaften, Halle an der Saale, Germany, Hohn Helmut ,   Programa de Pós-graduação em Geologia e Geoquímica (PPGG) do Instituto de Geociências da Universidade Federal do Pará, Belém, Pará, Brasil
Published: January 2022

The diamond alluvium gravels from the Painin garimpos, on the right bank of the Tapajós River, in Itaituba, Pará, stand out for the marked presence of pebbles from <1 cm to about 10 cm in diameter consisting of aluminum phosphate-sulfates (APS minerals) from the alunite supergroup: goyazite-florencite-gorceixite-crandallite-esvanbergite/woodhouseite. They are light gray pebbles, still containing small amounts of pyrite, kaolinite, goethite and anatase. The total chemical and trace element analyzes confirm the indicated mineralogical constitution alongside the XRD. The florencite member is mainly dominated by Ce, La, Nd and Sm, the light rare earth elements, and also contains anomalous concentrations of Nb, Y, Pb, U and Th. This chemical nature of these pebbles, in part, makes it possible to compare them with the diamond satellite beans (favas) in secondary deposits in Brazil, but chemically only with the phosphates from Malawi and Sayan.
DEVELOPMENT OF RAINFALL FORECASTING MODEL USING MACHINE LEARNING WITH SINGULAR SPECTRUM ANALYSIS
Authors: Reddy Pundru Chandra Shaker , Yadala Sucharitha , Goddumarri Surya Narayana
Published: January 2022

Agriculture is the key point for survival for developing nations like India. For farming, rainfall is generally significant. Rainfall updates are help for evaluate water assets, farming, ecosystems and hydrology. Nowadays rainfall anticipation has become a foremost issue. Forecast of rainfall offers attention to individuals and knows in advance about rainfall to avoid potential risk to shield their crop yields from severe rainfall. This study intends to investigate the dependability of integrating a data pre-processing technique called singular-spectrum-analysis (SSA) with supervised learning models called least-squares support vector regression (LS-SVR), and Random-Forest (RF), for rainfall prediction. Integrating SSA with LS-SVR and RF, the combined framework is designed and contrasted with the customary approaches (LS-SVR and RF). The presented frameworks were trained and tested utilizing a monthly climate dataset which is separated into 80:20 ratios for training and testing respectively. Performance of the model was assessed using Root Mean Square Error (RMSE) and Nash–Sutcliffe Efficiency (NSE) and the proposed model produces the values as 71.6 %, 90.2 % respectively. Experimental outcomes illustrate that the proposed model can productively predict the rainfall.
ABSTRAK:Pertanian adalah titik utama kelangsungan hidup negara-negara membangun seperti India. Untuk pertanian, curah hujan pada amnya ketara. Kemas kini hujan adalah bantuan untuk menilai aset air, pertanian, ekosistem dan hidrologi. Kini, jangkaan hujan telah menjadi isu utama. Ramalan hujan memberikan perhatian kepada individu dan mengetahui terlebih dahulu mengenai hujan untuk menghindari potensi risiko untuk melindungi hasil tanaman mereka dari hujan lebat. Kajian ini bertujuan untuk menyelidiki kebolehpercayaan mengintegrasikan teknik pra-pemprosesan data yang disebut analisis-spektrum tunggal (SSA) dengan model pembelajaran yang diawasi yang disebut regresi vektor sokongan paling rendah (LS-SVR), dan Random-Forest (RF), ramalan hujan. Menggabungkan SSA dengan LS-SVR dan RF, kerangka gabungan dirancang dan dibeza-bezakan dengan pendekatan biasa (LS-SVR dan RF). Kerangka kerja yang disajikan dilatih dan diuji dengan menggunakan set data iklim bulanan yang masing-masing dipisahkan menjadi nisbah 80:20 untuk latihan dan ujian. Prestasi model dinilai menggunakan Root Mean Square Error (RMSE) dan Nash – Sutcliffe Efficiency (NSE) dan model yang dicadangkan menghasilkan nilai masing-masing sebanyak 71.6%, 90.2%. Hasil eksperimen menggambarkan bahawa model yang dicadangkan dapat meramalkan hujan secara produktif.
CLASSIFICATION MODEL FOR BREAST CANCER MAMMOGRAMS
Authors: Mohamad Samuri Suzani , Nova Try Viananda , Rahmatullah Bahbibi , Wang Shir Li , Al-Qaysi Z.T
Published: January 2022

Machine learning has been the topic of interest in research related to early detection of breast cancer based on mammogram images. In this study, we compare the performance results from three (3) types of machine learning techniques: 1) Naïve Bayes (NB), 2) Neural Network (NN) and 3) Support Vector Machine (SVM) with 2000 digital mammogram images to choose the best technique that could model the relationship between the features extracted and the state of the breast (‘Normal’ or ‘Cancer’). Grey Level Co-occurrence Matrix (GLCM) which represents the two dimensions of the level variation gray in the image is used in the feature extraction process. Six (6) attributes consist of contrast, variance, standard deviation, kurtosis, mean and smoothness were computed as feature extracted and used as the inputs for the classification process. The data has been randomized and the experiment has been repeated for ten (10) times to check for the consistencies of the performance of all techniques. 70% of the data were used as the training data and another 30% used as testing data. The result after ten (10) experiments show that, Support Vector Machine (SVM) gives the most consistent results in correctly classifying the state of the breast as ‘Normal’ or ‘Cancer’, with the accuracy of 99.4%, in training and 98.76% in testing. The SVM classification model has outperformed NN and NB model in the study, and it shows that SVM is a good choice for determining the state of the breast at the early stage.
ABSTRAK: Pembelajaran mesin telah menjadi topik yang diminati dalam penyelidikan yang berkaitan dengan pengesanan awal kanser payudara berdasarkan imej mamogram. Dalam kajian ini, kami membandingkan hasil prestasi dari tiga (3) jenis teknik pembelajaran mesin: 1) Naïve Bayes (NB), 2) Neural Network (NN) dan 3) Support Vector Machine (SVM) dengan 2000 imej digital mammogram hingga teknik terbaik yang dapat memodelkan hubungan antara ciri yang diekstraksi dan keadaan payudara ('Normal' atau 'Cancer') dapat diperoleh. Grey Level Co-occurrence Matrix (GLCM) yang mewakili dua dimensi variasi tahap kelabu pada gambar digunakan dalam proses pengekstrakan ciri. Enam (6) atribut terdiri dari kontras, varians, sisihan piawai, kurtosis, min dan kehalusan dihitung sebagai fitur yang diekstrak dan digunakan sebagai input untuk proses klasifikasi. Eksperimen telah diulang selama sepuluh (10) kali untuk memeriksa kesesuaian prestasi semua teknik. 70% data digunakan sebagai data latihan dan 30% lagi digunakan sebagai data ujian. Hasil setelah sepuluh (10) eksperimen menunjukkan bahawa, Support Vector Machine (SVM) memberikan hasil yang paling konsisten dalam mengklasifikasikan keadaan payudara dengan betul sebagai 'Normal' atau 'Kanser', dengan akurasi 99.4%, dalam latihan dan 98.76% dalam ujian. Model klasifikasi SVM telah mengungguli model NN dan NB dalam kajian ini, dan ia menunjukkan bahawa SVM adalah pilihan yang baik untuk menentukan keadaan payudara pada peringkat awal.
EVALUATION OF SURFACE ROUGHNESS AND MATERIAL REMOVAL RATE IN ELECTRICAL DISCHARGE MACHINING OF AL-ALLOY WITH 10%SIC
Authors: Fadhil Abbas
Published: January 2022

Aluminum-based metallic matrix compounds are widely used in industrial and aircraft manufacturing due to their advanced characteristics, such as toughness and high strength resistance to weight ratio, etc. Silicon carbide is an important industrial ceramic and it is the fourth hardest ceramic after diamond, boron nitride, and boron carbide. Owing to its low fracture toughness, it is difficult to machine silicon carbide using traditional machining processes. Electrical discharge machine can machine such materials irrespective of their hardness. Aluminum alloy 6061 and 10% SiC based-metal matrix composite were used as a workpiece that was produced by stir casting. In the experimental investigation, pulse current Pc (10, 20, and 30 A), pulse on (Pon) duration (100, 150, and 200 ?sec), and pulse off (Poff) duration (6, 12, and 24 ?sec) were treated as the input variables. The output responses were surface roughness (SR) and material removal rate (MRR). The best value for surface roughness (Ra) reached (1.032 µm) at Pc (10 A), Pon duration (100 ?sec) and Poff (15 ?sec). Also, the best result for the productivity of the process (MRR) reached (69.49 × 10-3 g/min) at Pc (30 A) Pon, (200 ?sec) and (6 ?sec) Poff. Therefore, the experimental outcomes were optimized for surface roughnes and material removal rate by adding 10% SiC to aluminum alloy 6061. ABSTRAK: Sebatian matrik logam berasaskan aluminium telah digunakan secara meluas dalam industri pembuatan dan pesawat kerana ciri-cirinya yang canggih, seperti ketahanan dan daya rintangan yang tinggi kepada nisbah berat, dan lain-lain. Silikon karbida adalah seramik industri yang penting dan ia merupakan seramik keempat terkuat setelah berlian, boron nitrida dan boron karbida. Disebabkan ketahanan frakturnya yang rendah, adalah sukar bagi menghasilkan mesin silikon karbida menggunakan proses pemesinan tradisional. Mesin pelepasan elektrik mampu menghasilkan mesin menggunakan bahan tersebut tanpa mengira kekerasan. Aloi aluminium 6061 dan komposit matrik logam berasaskan SiC 10% telah digunakan sebagai bahan kerja yang terhasil melalui tuangan kacauan. Melalui penyelidikan eksperimen, detik arus Pc (10, 20, dan 30 A), detik hadir (Pon) berdurasi (100, 150, dan 200 ?sec), dan detik henti (Poff) berdurasi (6, 12, dan 24 ?sec) dirawat sebagai pemboleh ubah input. Respon pengeluaran adalah kekasaran permukaan (SR) dan kadar penyingkiran bahan (MRR). Nilai terbaik bagi kekasaran permukaan (Ra) telah mencapai (1.032 µm) pada Pc (10 A), berdurasi Pon (100 ?sec) dan Poff (15 ?sec). Tambahan, hasil terbaik bagi proses produktiviti (MRR) mencapai (69.49 × 10-3 g/min) pada Pc (30 A) Pon, (200 ?sec) dan (6 ?sec) Poff. Oleh itu, hasil eksperimen dioptimumkan bagi permukaan kasar dan kadar penyingkiran bahan dengan tambahan 10% SiC ke aloi aluminium 6061.
A Window in the Heart Is Sometimes a Good Start: It’s Not Always Sepsis
Authors:   Department of Medicine, State University of New York, Upstate Medical University, Syracuse, New York, USA, Khanal Subrat , Al-Khalisy Hassan ,   Department of Pulmonary and Critical Care, State University of New York, Upstate Medical University, Syracuse, New York, USA
Published: January 2022

Cardiac tamponade is a life-threatening compression of the heart caused by abnormal accumulation of pericardial fluid. Important elements affecting its disposition and treatment are the rate of fluid accumulation relative to pericardial stretch and the effectiveness of compensatory mechanisms before critical hemodynamic compromise occurs. It is a clinical diagnosis and waiting for the threshold of steep rise in cardiac transmural pressure to critical levels may lead to catastrophic outcomes which is why early drainage has to be strongly considered in suspected cases.
Features of Controlling Providing and its Implementation in the Enterprise Management System
Authors:   Kyiv National University of Trade and Economics, Bieliaieva Nataliia , Khmurova Viktoriia ,   Kyiv National University of Trade and Economics
Published: January 2022

Annotation. Introduction. Features of the modern world require leaders to make decisions in difficult circumstances like crisis, dynamic environment, pandemic. For managers at all levels, issues of forecasting the development of the situation, timely response to changes, etc. are becoming more acute. Purpose. The implementation of a controlling system cannot solve all the issues because the implementation is not enough. The process of providing and implementing a combination of automated systems, quality information and highly qualified personnel to help companies maintain their market position remains important. Results. The introduction of automated controlling systems significantly improves the quality of management decisions. Determining the prospects of development requires a combination of reliable information from all departments of the enterprise and elimination of shortcomings quickly. Controlling needs special attention: in the "planning" functional area - increasing funds turnover; in the "accounting" functional area -savings to prevent possible losses; in the "analysis" functional area - additional income; in the "control" functional area - to avoid penalties; in the "monitoring" functional area - additional income; in the "integration" and "coordination" functional areas - the cost of released economic resources; in the "consulting" functional area - the cost of reducing the likelihood of negative consequences; in the "information support" functional area – actual information for decision making process. Features of controlling support at the enterprise are: qualified personnel, current issues of enterprise development, the availability of suppliers’ base, access to legislation changes and more. Conclusions. As a result, it is determined that in addition to the system itself, it is necessary to comply with the requirements for each process where controlling is implemented. The results of controlling realization at the enterprise are a reduction in reaction time to changes in the external and internal environment, as well as a reduction of management risk.
International disclosure practices in reporting under COVID 19
Authors:   Kyiv National University of Trade and Economics, Kostyuchenko Valentyna
Published: January 2022

Abstract. Introduction. The outbreak of COVID-19 has forced every country to impose strict measures to curb the spread of the virus, most countries have closed their borders, imposed restrictions on business, cut off transport, and these circumstances are extremely important for disclosure in financial statements, and complicate the process its compilation. Thus, these challenges and current conditions contribute to the importance of providing high quality information, as users of financial statements need timely, high quality and complete information, which is compiled through the prism of COVID-19 impact on the company, its financial condition, liquidity and future prospects. Purpose. Generalization of international disclosure practices in financial statements under COVID-19 and recommendations for resolving problems arising from the pandemic and affecting the reporting of economic entities. Results. Summarizing the recommendations provided in Australia and Belgium professional organizationsac, companies are required to disclose material uncertainties related to COVID-19 in their financial statements, including assessing the impact of the pandemic on the enterprise, identifying countermeasures taken and showing the impact on the Company's future operations. For goodwill impairment tests and other vulnerable items, the disclosure of material assumptions should be provided in sufficient detail, together with a description of the approach to determining the value assigned to each key assumption. These include assumptions about the duration and intensity of the effects of the cessation of operations and the recovery phase. The entity will also need to explain the significant impact of COVID-19 on the risks associated with the financial instruments and how it manages those risks. Conclusions. Having determined that the pandemic has a significant impact on the financial performance of companies around the world, we conclude that the burden of using the best, most accurate, truthful and accessible information in making sound and validated judgments and estimates that take into account the effects of the COVID-19 pandemic.
Economic Analysis of Macroeconomic Trends: China and India
Authors:   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Manaienko Iryna , Ivanova Anastasiia ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Burtova Anastasiia ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute»
Published: January 2022

Abstract. Introduction. Nowadays the world is on the cusp of major changes. The eastern market is becoming much more popular, important and powerful for the international community. India and China are already openly fighting for world domination through the dynamic growth of their own economic and military potential. It should be noted that, it was important for a detailed analysis of the economies of these eastern countries not only to process statistics, but also to take into account traditions and culture. Purpose. The main idea of this article is to understand clearly the aspects of further development of the world economy and to identify economic risks and trends, analyzing the following macroeconomic indicators of eastern giants’ countries. Results. A detailed analysis of the dynamics of GDP’s changes over the past 5 years was conducted and once again emphasized the power of these national economics that has only grown in recent decades. The importance of initiatives and innovations, creating by the eastern neighbors for the world community, was highlighted through a determination of the role of India and China in the integration international associations and study of the attracted investments. The interdependence of the world’s market and the eastern market of India and China was considered, a detailed breakdown of exports and imports of goods and services was carried out and that gives us the opportunity to identify the most important and most powerful groups of goods for today. Conclusions. The study identified similar aspects of the development of emerging economies such as India and China, which were supported by reports from objective sources of statistical information. Determining the macroeconomic situation of the next national economies allowed us to explain how the COVID-19 pandemic changed the action plan of the studied countries, to find weaknesses of strong enough economies, and also to make certain predictions about the future world market.
Theoretical Aspects of Night Audit at Hotel Enterprises
Authors:   Poltava University of Economics and Trade, Mikhailova Natalia , Volodko Olga ,   Poltava University of Economics and Trade, Rybakova Svitlana ,   Poltava University of Economics and Trade
Published: January 2022

Introduction. Hotels are luggage and service enterprises. To make the right management decisions and increase profits hospitality enterprises must have accurate, timely, and truthful information on the issues of commercial activities. The most effective way to obtain this information is possible when conducting a regular external audit. It is the quality of the current audit that determines the financial position of the state enterprise. Night audit is one of the areas of internal audit of hotel enterprises, aimed at ensuring the safety of assets, verifying the reliability of accounting information, improving the efficiency of operations, and their compliance with enterprise policy. Night audit is of particular importance for managers and owners of hotel enterprises, as it helps to assess the implementation of the objectives of production and economic activity. Purpose. The purpose of the article is to study the theoretical aspects of night auditing in the hotel industry. Methodology of research. The achievement of this goal was carried out with the help of general scientific and applied research methods, in particular: methods of scientific abstraction - to substantiate the essence and significance of night audit as an aspect of internal control in the hotel industry; methods of logical generalization - to determine the main tasks of the night audit; methods of systematization, detailing and grouping - to consider the methods and basic functions of night auditing. Results. Analyzing and systematizing the scientific works of many scientists, the essence, purpose, and tasks of night audit were determined, the technology and methods of night audit of the hotel were considered, the main competencies of night auditor in the process of control operations were clarified. Conclusions. The practical significance of the obtained results is to determine the need to introduce the practice of night audit as a full-fledged type of control. The scientific novelty of the research results is the deepening of the theoretical foundations of night audit technology to improve the accounting and control support of the management system of the hotel industry. Further research will focus on the detailed implementation of night audit automation in hotel activity.
Financial Leasing as a Guarantee of Development of the Agricultural Sector Economy of Ukraine
Authors:   Mykolayiv National Agrarian University, Sirenko Natalia , Mikuliak Kateryna ,   Mykolayiv National Agrarian University, Gannichenko Tetiana ,   Mykolayiv National Agrarian University, Polishchuk Alina ,   Mykolayiv National Agrarian University
Published: January 2022

Annotation. Introduction. It was found that the promising direction of renewal of fixed assets and the provision of a number of additional services for the agricultural sector is financial leasing. The essence of financial leasing, the subjects involved in its implementation, as well as regulatory support are analyzed. The advantages and disadvantages of financial leasing are systematized. The dynamics of changes in the share of the value of financial leasing agreements concluded by industries and equipment is presented. The foreign experience of financial leasing as an attractive and effective instrument of financial investments is generalized. Purpose. The purpose of the study is to reveal the essence and features of financial leasing as one of the promising tools for the development of agricultural sector entities, to upgrade equipment and provide a number of additional services.Results. The article explores the realities and identifies prospects for the provision of financial leasing services to the agricultural sector of Ukraine, as an important tool for updating production assets and providing additional services. The advantages and disadvantages of financial leasing operations are systematized. The world experience of financial leasing as an attractive and effective tool of financial investments in production assets is considered. Conclusion. The growth of the financial leasing market for the provision of services to agricultural entities will be due to the resumption of economic activity and the promotion of the benefits of this form of financing capital investments. Raising consumer and small and medium-sized business awareness of leasing as a tool for access to finance should be a priority for the leasing industry, its association and the government.
State Support for the Agricultural Sector in Terms of Strengthening its Economic Security
Authors:   National Agrarian University named after V.V. Dokuchaiev, Utenkova Karina
Published: January 2022

Abstract. Introduction. The article is devoted to the problems of ensuring the appropriate level of state support for the agricultural sector in the context of strengthening its economic security. The purpose of the article is to reveal the organizational principles of state support for the agricultural sector, analysis of its effectiveness. Results. The importance of ensuring the appropriate level of state support for the agricultural sector in terms of strengthening and economic security further development has been substantiated. The forms of state support for the agricultural sector have been considered in the article. The programs with the help of which the state support for the agricultural sector is carried out today have been analyzed. The dynamics of state funding of individual programs to support domestic farmers has been studied. The period 2010-2019 there was a constant underfunding of the planned amounts of state support for the agricultural sector. The negative dynamics of activity indicators of the agricultural sector enterprises since 2015 has been revealed, which was caused by the imperfect mechanism of state industry support. The results of the program implementation of financial support of agricultural producers in partial compensation of machinery and equipment cost of domestic production have been studied, as well as the analysis of the programs of cheaper loans in the agricultural sector of Ukraine. Conclusions. It has substantiated that one of the main tasks for today is to develop a normative document that will determine the key aspects for further strengthening the economic security of the agricultural sector and will be a part of Ukraine's agricultural policy. Thus, the development of the Strategy for the economic security development of the agricultural sector will determine the main directions for further industry development and create an effective mechanism for managing the economic security of the agricultural sector. One of the key areas of strategy implementation should be: ensuring sufficient state support for the agricultural sector, its permanent implementation and affordable conditions, further expansion of state support, as well as increasing its volume to the necessary limits; as well as the formation of financial and credit support for the agricultural sector development on an institutional basis.
Working-out the Development of Investment Activities of Enterprises
Authors:   Simon Kuznets Kharkiv National University of Economics, Chernyshov V. V
Published: January 2022

Abstract. Introduction. In modern conditions of transformation of the national economy the development of investment activity, which influences the interests of a growing number of enterprises, becomes relevant. Effective implementation of investment activities at the present stage is the basis for the development of Ukraine's economy, ensuring the possibility of its integration into the European socio-economic space, which will further enhance the competitiveness of enterprises and improve the investment climate. Purpose. It has been proved that investment activity requires decision-making on investing financial resources to expand production. It has been established that the investment strategy of any enterprise is an integral part of its overall economic strategy, which allows to fully assess the investment potential for foreign investors. Results. An analysis of business entities based on indicators of investment activity in the selection of strategic development priorities. There are three clusters: first class: normal investment activity; second class: moderate investment activity; and third grade: critical investment activity. The analysis of investment activity of business entities of the machine-building industry in Ukraine indicates the need to attract investment resources. Conclusions. Hierarchies of choice of strategic priorities directions of development for attraction of foreign economic sources of financing have been offered and its economic efficiency has been established. The hierarchy of communication of the choice of directions of strategic development priorities for attracting foreign economic sources of financing has been obtained, which has six levels, where the highest level is to ensure the development and promotion of products of economic entities in international markets. Implementation of 6 levels of the hierarchy of choice of strategic development priorities to attract foreign economic sources of financing of economic entities, these are comprehensive actions that will enhance investment attractiveness in international markets and address some issues related to the development of strategic priorities of economic entities.
Development of the Insurance Market in Ukraine in the Context of Transformation Changes
Authors:   Mykolayiv National Agrarian University, Shyshpanova Nataliia , Bodnar Olena ,   Mykolayiv National Agrarian University
Published: January 2022

Abstract. The article substantiates the feasibility of ensuring the development of the insurance market in Ukraine in the context of digital transformations. It has been determined that the latest digital technologies are penetrating deeper into the global insurance market, without bypassing any area of activity, but the volume of the insurance market in Ukraine is several times less than in the developed countries of the world. The indicated factors which restrain the development of the insurance market in Ukraine and characterized existing problems of the insurance market lead to low confidence in the companies of the sector and do not allow it to develop properly. It has been established that in modern conditions of digital transformations, insurance companies widely use innovative technologies that ensure the achievement of both short-term effects and long-term competitive advantages. The directions of digitalization of the insurance market in Ukraine have been characterized and it has been substantiated that the processes of digital transformation based on the development of information technologies of insurance companies contribute to increasing competitiveness. In order to improve the situation in the domestic insurance market and maintain competitive positions, insurance companies should actively use European and world experience, introduce and change models of insurance functioning, and intensively introduce innovative technologies in insurance activities. The use of new technologies and management models in practice will increase the efficiency of the provision of insurance services, require insurance companies to develop new insurance products, taking into account the individual wishes of customers, and will also contribute to expanding the scope of using insurance as a method of risk transfer in an integrated risk management system, as well as will ensure the creation of a unique competitive advantage for those insurance companies that are able to introduce innovative digital technologies in accordance with the individualized requests of customers
Intestine epithelial cell-Derived Extracellular Vesicles alleviate Inflammation Induced by Clostridioides Difficile TcdB through the Activity of TGF- β1
Authors: Jin Dazhi , Wan Shuangshuang , Song Guangzhong , Hu Hui , Xu Yaqing , Zeng Peng , Lin Shan , Yang Jun , Jiang Jinqin , Song Xiaojun
Published: January 2022

Background: Clostridioides difficile infection (CDI) has been primarily associated with the toxin B (TcdB), which can activate the intestinal immune system and lead to pathological damage. Even though the biological functions of intestine epithelial cell- derived extracellular vesicles (I-Evs) have been well documented, the role of I-Evs in the process of CDI is still unknown. Results: We isolated I-Evs ranging from 100–200 nm in mean diameter, with a density of 1.09-1.17 g/mL. These I-Evs expressed the extracellular vesicle-associated specific surface markers, CD63 and TSG101. In vitro, 50 µg I-Evs decreased the expression of IL-6, TNF- β, IL-1β, and IL-22 in MC38 induced by 0.8 ng/mL C. difficile TcdB, and increased expression of TGF- β1. In vivo, I-Evs also promoted regulatory T cell induction, which improved inflammation of mice up to 80% relative to C. difficile TcdB infected mice, depending on the TGF- β1 signal pathway. Conclusion: Our study firstly demonstrated that I-Evs originated from intestine epithelial cells is potentially a novel treatment endogenous candidate to effectively reduce the local infection induced by C. difficile TcdB.
Re-Print-Anaphylaxis Induced by Beer
Authors: L Navarro , C Lazo , P Pineda , M Labrador-Horrillo , A Roger , M Basagaña
Published: January 2022

The prevalence of cereal allergy is highly influenced by geographical area and consumption habits. According to data from Alergologica 2015 [1], cereal allergy accounts for 2.1% of all cases of food allergy in Spain. Beer is a barley-based alcoholic beverage that also contains hops, yeast, and other cereals (wheat, oats, corn, and even rye). Barley is also the basis of malt vinegar, whiskey, and gin. Several allergens of barley have been described, including lipid transfer protein (LTP), - and ß-amylase, gliadin, glutenin, peroxiredoxin, thionin, and trypsin inhibitor [2].
Precocious Puberty: Causes, Consequences, Daily Environmental Factors, and the need for Community/Societal Support
Authors: Bidaisee Satesh , Y. Huang Stephanie , Pichainarongk Siriluk
Published: January 2022

Precocious puberty, otherwise described as a group of medical conditions that cause early puberty onset, such as a pre-adolescent boy presenting with adult pattern of penile and testicular enlargement or a pre-adolescent girl presenting with mature breast development and onset of menses. Although the sexual and physical characteristics for this condition are well-described in medical literature, the causes are very rarely known. Nevertheless, it has substantial impacts on children’s lives. This is a review on sexual development, premature sexual development, the social complications children suffer from due to early onset puberty, and the associations with daily environmental exposures as possible influences for developing precocious puberty.
Routes of Infections, Inflammation, Immunity, Immunity Response and Inflammatory Injury: Elucidation of a Biological Fight
Authors: Kumar Rajiv
Published: January 2022

Infections, inflammation, immunity, and inflammatory injury are different segments of biological events and link up altogether. Route of infection has no similarity with the cellular signaling pathway of inflammation, even though when inflammation is induced by infection. The organism responds toward infection that is initiated by the pathogen via inflammation, which is a natural way of defense initiated by innate immunity as a safeguard
Stable Angina Pectoris: One-Year Outcomes of Patients with Obstructive Coronary Artery Disease: Multicenter Sutdy in Dakar (Senegal)
Authors: HESSOU Paul Coffi , MINGOU Joseph Salvador , DIAO Maboury , AW LEYE Fatou , NDIAYE Mouhamadou Bamba , SARR Simon Antoine , BODIAN Malick , NDIAYE Papa Guirane , HESSOU Paul Coffi , DIACK Bouna , MBAYE Allasane , NGAÏDE Aliou Alassane
Published: January 2022

Background: CAD management is important in prevention of disease progression. But we have very little study or research on the evolution of stable angina in amulatory patients without coronary antecedents and with obstructive coronary disease. Purpose: The objective of our study was to analyze the clinical and angiographic profil of patients with stable chest pain and to assess their angina status one year outcomes. Patients and methods: All patients who presented with symptomatic angina pectoris and/or signs of ischemia and first diagnosis of obstructive CAD in the Cardiology Departments of Idrissa Pouye General Hospital and Aristide Le Dantec National University Hospital Center of Dakar, from March 01, 2019 to December 31, 2020 were selected. The clinical characteristics, initial angiographic findings, therapeutic strategy and outcome within the first year were analyzed. Results: During the study period, 84 outpatients presenting with symptomatic stable chest pain and first obstructive coronary artery disease were selected. The mean age was 63.01± 9.37 years. Male preponderance was observed with 63(75%) patients; Clinical symptoms were dominated by typical pain with 46.4% (n=39) ; the risk factors were dominated by hypertension 61.9% (n=52); diabetes 41.7% (n=35) and dyslipidemia 33.3% (n=28). During follow-up, 10 patients (11.90%) remained untraceable while 9 patients (10.71%) were not available for check-up; 3 patients (3.57%) died during follow-up. Only 62 patients (73.80) could be evaluated; among those who were alive and controlled, 26 patients (41.93%) with angina at baseline still had angina symptoms, 2 patients (3.22%) had undergone myocardial infarction; one (1.61%) had undergone urgent revascularization; one (1.61%) patient developed heart failure. Finally 32 patients (51.61%) were event-free and angina-free Conclusion: The management of outpatients with stable chest pain and first obstructive CAD appears favourable, with good adherence to guideline-based therapies one year outcomes. Stable chest pain is not associated with an increased risk for adverse cardiovascular outcomes but there remains room for improvement in terms of risk factor control.
Echocardiographic and Computed-tomographic Evaluation of the Fate of Bovine Pericardial Patch as a Pericardial Substitute in Bentall’s Procedure: Twenty-year’ Results
Authors: K. Chowdhury Ujjwal , Goja Shikha , Sankhyan Lakshmi Kumari , Pandey Niraj Nirmal , Arava Sudheer , Sharma Srikant , Chauhan Abhinavsingh , Malik Vishwas
Published: January 2022

Objective: The study was designed to ascertain the influence of usage of bovine pericardial patch in patients undergoing Bentall’s procedure with respect to reexploration for bleeding, mediastinal infection, avoidance of conduit adhesions, late development of pericardial constriction and calcification. Materials and Methods: We reviewed 150 patients (79 males) aged between 22 to 68 years (mean±SD 49.25±12.9 years) receiving a composite aortic conduit between January 1998 to December 2020 for annuloaortic ectasia (n=100), aortic dissection (n=49), and dilated aortic root in repaired tetralogy of Fallot (n=1). Twenty-five patients had Marfan’s syndrome. Modified “button technique” was performed by interposing a glutaraldehyde treated pericardial strip at the graft coronary anastomoses, and proximal aortic conduit suturing using interlocking interrupted, pledgeted mattress suture. On completion, the pericardial cavity was reconstructed using St. Jude Medical Biocor pericardial patch. To detect evidence of pericardial constriction, survivors underwent echocardiography and computed tomography. The Kaplan-Meier curve was drawn to show the probability of survival over a period of follow-up time. Results: Seven (4.7%) patients died of cardiac-related cause, 45% had transient hemodynamic instability, 55% had low cardiac output, and 87.1% had spontaneous return of sinus rhythm. The average 12-hour postoperative drainage was 245±70 ml and there was no mediastinal infection. At a mean follow-up of 172.4 (SD± 58.9) months, the actuarial survival was 94.2±0.04% (95% CI: 88.5-96.8), and there was no pericardial constriction or calcification. Conclusion: Reconstruction of pericardial cavity using Biocor bovine pericardial patch minimizes diffuse oozing of blood, graft infection, and is not associated with later development of pericardial constriction, or calcification.
Myopericarditis as an Extra-Intestinal Manifestation of Crohn’s Disease: A Case Report
Authors: Prasad Rohan , Chennupati Surya , Kemnic Tyler , Al-abcha Abdullah , Boumegouas Manel , Kavuturu Shilpa
Published: January 2022

Introduction: Myopericarditis is an uncommon manifestation of Crohn’s disease. Interestingly enough, it can present in a patient without any acute bowel symptoms. Case Presentation: A 21-year-old male with a medical history of Crohn’s disease and eosinophilic esophagitis presented to the hospital with chest pain and fever. Blood work revealed elevated troponin, C-reactive protein, and sedimentation rate levels. Electrocardiogram (EKG) showed diffuse ST elevation in all leads. Transthoracic echocardiogram (TTE) demonstrated a small pericardial effusion without valvular abnormalities. The patient was diagnosed with myopericarditis. Extensive etiological workup was negative, in the absence of other explanations, it was attributed to his Crohn’s disease. The patient was started on colchicine and ibuprofen. Out-patient follow-up revealed resolution of symptoms. Conclusion: This case reports the rare occurrence of myopericarditis and Crohn’s disease. Inflammatory bowel disease as a cause of myopericarditis has been reported in some cases within the literature; however, there is no definitive mechanism known.
Knowledge, Beliefs and Practices of People diagnosed with Type-1 Diabetes towards Diabetes Mellitus and Diabetic Foot Syndrome
Authors: Unni Shiju Raman , Naguib Hani , Mccallum Mary
Published: January 2022

Background: Diabetes Mellitus (DM) is associated with significant morbidity and mortality. Diabetic foot syndrome is one of the most common devastating preventable complications of diabetes mellitus (DM). Objectives: We aimed to evaluate the knowledge, Beliefs and Practices (KBP) among Omani patients with type 1 diabetes mellitus (T1DM) regarding DM and Diabetes foot. Design: A cross sectional descriptive study was used. Settings: A secondary care, polyclinic named Bawshar in Muscat, Oman where patients were seen three days per week. Sample Size:A convenient sample of 100 participants between age group 16 to 30 years were involved. Materials and methods: A validated semi- structured questionnaire was used to assess KBP of T1DM with six domains. During the study period from November 2019 to December 2019. .The data was analysed by using Statistical Package for the Social Sciences (SPSS) Statistics Inc., Chicago, US version 20. Results: There were 50 females, 50 males; 5 % of patients were illiterate and 30% of them were working. 65% were students. Only 50% checked their foot regularly and only 55% check there blood glucose regularly .57% don’t know the cause of diabetes, 25% don’t know the complications of the same while 20% don’t know cause of diabetic foot and 25% don’t know the symptoms of diabetic foot. 20% beliefs checking blood glucose is the responsibility of the doctor and 85% beliefs walking bare foot is high risk factor for DM foot. Conclusions: In reality healthcare providers must be trained to counsel people with DM to plan adequate interventions that enable an understanding of the offered information. A well-structured ,Behaviour change counselling (BCC) like Motivational interviewing (MI)are considered the ideal practices for this patients, to prevent DM complications.
Osteoporosis Prevalence and Correlates in Uncomplicated Type 2 Diabetes Mellitus
Authors: Nachankar Amit , Sahu Jitendra
Published: January 2022

Type 2 Diabetes Mellitus (T2DM) is a common metabolic disorder at a pandemic proportion at present. Often T2DM is associated with microvascular (diabetic nephropathy, neuropathy, and retinopathy) and macrovascular complications (coronary artery disease, peripheral arterial disease, and stroke). Additionally diabetic osteopathy is a significant comorbidity of T2DM and is characterized by micro architectural changes that decrease bone quality leading to an increased risk of fragility fracture.
Role of Insulin: Perspectives
Authors: Bereda Gudisa
Published: January 2022

The pancreas in a non-diabetic patient invariably produces a lesser quantum of insulin (basal production). Insulin furnishes glucose homeostasis by keeping the plasma glucose worth in an optimum class throughout the day. It assists transport blood glucose into the body cells where the glucose is metabolized to generate energy. Regular insulin is inserted pre-meal to abrupt the postprandial ascend in glucose levels. It figures hexamers after insertion into the subcutaneous space sluggishing its absorption. Ultra-fast acting commences to act 4-7 minutes before regular apidra and lasts for around 3 hours. The absorption rate of lente insulin is downgraded by the extension of zinc to the insulin preparation. Long-acting insulins furnish basal insulin coverage. Atrophy of subcutaneous fat owing to applicability of further greater accumulated insulin preparations of neutral potenz hydrogen.