bluuebunny/crossref_metadata_2025 huggingface dataset:
A review: CRISPR/Cas12-Mediated Genome Editing in Fungal Cells: Advancements, Mechanisms, and Future Directions in Plant-Fungal Pathology
Authors: Agarwal Chiti
Published: June 2023

The CRISPR-associated protein system (CRISPR/Cas), characterized by clustered regularly interspaced short palindromic repeats, has revolutionized life science research by providing vast possibilities for alteringspecific DNA or RNA sequences in various organisms. The present system integrates fragments of exogenous DNA, known as spacers, into CRISPR cassettes. These cassettes are subsequently transcribed into CRISPR arrays, which are further processed to generate guide RNA (gRNA). The CRISPR arrays are genetic loci that are responsible for encoding Cas proteins. The Cas proteins are responsible for supplying the necessary enzymatic machinery to acquire new spacers that are aimed at invading elements. The development of novel genome engineering tools has been made possible by utilizing various Cas proteins, including but not limited to Cas9, Cas12, Cas13, and Cas14, which possess programmable sequence specificity. The emergence of Cas variants has spurred genetic research and advanced the utilization of the CRISPR/Cas tool to manipulate and edit nucleic acid sequences within a wide range of living organisms. This review aims to furnishoperational modalities ofthe Cas12 protein identified thus far. Furthermore, the advantages and disadvantages ofCas12proteinare examined, along with their recent implementations in the plant fungal world.
Unleashing the Potential of Chickpea Disease Resistance Breeding
Authors: Agarwal Chiti
Published: June 2023

Chickpea (
Cicer arietinum L.) is an ancient legume crop with a rich history of domestication and cultivation. Understanding the origin and history of chickpea provides valuable insights into its genetic diversity and adaptation to diverse environments. This review explores the domestication process, geographic distribution, and historical significance of chickpea. Furthermore, it highlights the role of molecular breeding in harnessing the genetic potential of this crop. The use of molecular markers and advanced genomic tools has revolutionized breeding efforts, enabling the identification of key traits and the development of improved disease resistant varieties. The review also discusses the advancements that have accelerated progress in chickpea improvement. Insights from genomic studies have unraveled the genetic basis of biotic stress tolerance. The integration of genomics with conventional breeding methods has paved the way for efficient selection and accelerated the breeding process. Finally, the review discusses the future prospects and potential applications of molecular breeding in chickpea improvement, including the utilization of genomic selection and genome editing techniques. Understanding the domestication and molecular breeding history of chickpea provides a foundation for the development of superior varieties with enhanced productivity, quality, and resilience to biotic stresses. This knowledge contributes to the overall goal of sustainable chickpea production and food security.
New Consideration of the Skin Effect in Electrodynamics
Authors: Maslov Sergey , Maslov Iurii , Maslov Dmitry
Published: June 2023

The article proposes an approach to solving the normal skin effect problem based on integral equations derived directly from Ampère's circuital law, Faraday's law of induction and Kirchhoff's circuit laws, in contrast to modern solutions based on Maxwell's equations of electrodynamics in differential form. It is shown that the skin effect is mainly due to the electromotive force of the wire self-induction, which depends on the distance to the surface, and the influence of eddy currents is either very small or absent. New equations, their solutions and formulas for the total current and impedance are proposed for various technically significant cases immediately taking into account the inductance of the external space and in two versions: taking into account only the self-induction of the conductor; taking into account both self-induction and eddy currents. On the example of a solid cylinder, it is shown that, in accordance with the formulas of the existing approach itself, the current density on the surface of the wire does not increase with increasing frequency, as it is stated in words. It is shown that, in fact, the solutions of the existing concept are based not on eddy currents, but on the uneven distribution of elementary self-induction currents over depth and are completely equivalent to the variant of the presented solutions, taking into account only self-induction. Power balances were obtained without the introduction of a frequency-dependent active resistance to alternating current in two versions: based on the total current, voltage and average electromotive force of induction; based on the integration of the balance of specific powers over the entire volume of the wire. The physical meaning of the visual increase of the active resistance with increasing frequency is revealed, but certainly not on the basis of a decrease in the effective cross section of the wire. Based on the symmetry of the distribution of eddy currents, the assumption is made that they are absent in galvanically closed wires, but present in open wires such as antennas. An experiment was carried out with a negative result on the detection of the alleged thermal separation in the wire, an explanation for this was proposed.
A novel advertising approach and provision of a marketable product for the aviation industry
Authors: Kouppari Eleftheria , Fotiou Yiota , Zacharatos Haris
Published: June 2023

The relevance of the information offered at each step along the journey and the targeted information delivered to the user's device were critical indicators for the successful implementation of Motus platform. This approach offered a social graph that tracks users' online and offline actions throughout the journey, which was employed to instantly lead the system in delivering relevant data and promotions, along with other trip-related data. This one-kind platform directly categorises actual users' interests, personalizes the advertisement and provides a novel advertising approach adapted to the changing technologies, addressing many issues in both sectors (aviation and advertising). The successful implementation of the Motus platform in both connected and non-connected environments and the adaptation of the platform to the growing aviation and IFE markets initiated new revenue streams for commercial airlines. Furthermore, the creation of this marketable product in a unique selling point such as the aviation sector during flights closed the loop for advertisers, who thus far missed the opportunity to reach travellers in flight.
Improvisation of Finite element analysis for designing an After Fall Assistive Device for the Elderly Patients
Authors: Fakhouri Faisal , Fakhouri Abdulaziz , Ijaz Muhammad Farzik , Alotaibi Majed , Almalki Abdulqader
Published: June 2023

Falling on the ground can cause serious injuries such as bruises, broken bones, head injuries, etc. Annually 684,000 individuals die globally from falling on the ground. There are more than 37 million fall injuries that requires medical care each year. The Center for Disease Control and Prevention (CDC) anticipates seven fall deaths every hour by 2030. In Saudi Arabia, falls are the 6

th major cause of death, and the 7

th major cause of living with a disability. Furthermore, falling on the ground becomes a risk factor with age, obesity, and presence of balance affecting diseases due to fact that individuals have difficulty getting up after a fall, and the majority of them stay on the ground for more than an hour. As a result, the risk of multiple injuries, dehydration, pressure ulcers, rhabdomyolysis, hypothermia, and pneumonia increase. This study aims to design and analyze a device that can assist individuals, especially seniors, at risk to rise up after a fall on the ground with no external help from others. The design of the device was modelled using SolidWorks 2017 (Dassault Systems, Waltham, MA, US). Also, finite element analysis (FEA) was performed to study von Mises stresses and total deformation on the model. FEA results showed that the device could withstand to lift an overweight individual from the ground without reaching the maximum failure stress of a conventional material such as aluminum.
Testing of Inexpensive Nitrogen Chambers for Maintenance of Herbarium Specimens
Authors: Van Zant Miriam Kritzer , Lightfoot David A.
Published: June 2023

Inexpensive vacuum bags, designed to store fabrics and made from oxygen-barrier plastic, were repurposed as ambient temperature nitrogen chambers to neutralize pests on herbarium specimens. Combination t-test and ANCOVA results on data from oxygen-monitoring tablets indicated 0.1% anaerobia was maintained inside these bags for 39 days. Anaerobia below 0.3% oxygen maintained for up to 3 weeks deactivates insects, bacteria, and most molds. One or two small oxygen-absorber packets placed inside bags affected how quickly and reliably 0.1% anaerobia could be achieved and maintained. Three vs. six flushes with nitrogen had no statistically significant effect for achieving anaerobia.
La sociedad civil senegalesa y su implicación en el ámbito migratorio. El rol de las Organizaciones de la Sociedad Civil en acciones de sensibilización, formación y educación
Authors: Vallés Marugán Alba
Published: June 2023

La sociedad civil ocupa un lugar muy relevante en la esfera social y política en Senegal, siendo las migraciones uno de sus ámbitos de acción. Desde el terreno asociativo, las llamadas Organizaciones de la Sociedad Civil (OSC), se implican en distintas acciones, entre las que podemos destacar la sensibilización sobre los riesgos de la migración irregular, por un lado, y la formación de los jóvenes de cara a su inserción sociolaboral en Senegal, por el otro. Todo ello con el fin último de que la migración no sea considerada una necesidad, sino una opción más y, de hacerse, se haga por vías seguras y regulares. A partir del trabajo de campo cualitativo realizado con OSC de Dakar (Senegal), en este artículo reflexionaremos en torno a las acciones implementadas por estas entidades en estos dos campos, incorporando su planteamiento crítico y respetuoso con los derechos de las personas migrantes.
Migración y globalización del cristianismo chino: dinámicas locales y transnacionales de las iglesias cristianas chinas en Barcelona
Authors: Lamas-Abraira Laura
Published: June 2023

Este artículo constituye una primera aproximación al cristianismo chino en España a partir de un estudio de caso en el área metropolitana de Barcelona. Se contextualiza el fenómeno del cristianismo chino a través de una mirada que incorpora la esfera de lo local y lo transnacional, así como una comprensión de la práctica religiosa como hecho social. En base a una investigación cualitativa, este artículo da cuenta de los orígenes y lógicas organizativas de las iglesias cristianas chinas presentes en el área y de sus dinámicas sociales y retos actuales. Finalmente, se subraya la importancia del contexto migratorio, en el cual se inscriben, tanto a nivel de la experiencia individual como en su condición de comunidad religiosa.
La memoria social en el campo de los estudios migratorios de la Argentina: un estado de la cuestión (2001-2020)
Authors: Herrera Nicolás
Published: June 2023

La bibliografía especializada afirma que el interés del campo de los estudios migratorios por los procesos de recordación social comenzó a manifestarse, en Europa y los Estados Unidos, durante la primera década del siglo XXI. En la Argentina carecemos de estudios que analicen dicho proceso y presenten un estado de la cuestión sobre el mismo. El objetivo principal de este artículo es construir un estado de la cuestión que dé cuenta de las relaciones establecidas, durante las dos primeras décadas del siglo XXI, entre el campo de los estudios migratorios y el campo de estudios sobre la memoria social de la Argentina. Los resultados del artículo permiten describir la evolución de las relaciones establecidas entre ambos campos académicos, identificar los temas analizados por la bibliografía de referencia y, finalmente, mostrar cuáles han sido los logros alcanzados y las limitaciones que aún persisten al interior de esta área de estudios.
إسماعيل مظهر والبواكير الأولى للكتابات العربية المعاصرة عن جابر بن حيَّان
Authors: حسين نبيل فتحي
Published: June 2023

تقوم الفكرة الرئيسة لهذا البحث على التعريف بأقدم عمل عربي معاصر عن أبي عبدالله جابر بن حيَّان الكوفي المعروف بالصوفي (ت نحو ٢٠٠هـ/٨١٥م) الذي ارتبط اسمه بالكيمياء العربية الإسلامية، مؤسساً لها، ومقدِّماً لأعظم نتاج فيها، وهو مقال ذو طابع أكاديمي كتبه المفكر المصري المعاصر المعروف إسماعيل مظهر، ونُشر في مجلة "المُقتطَف"، في قسمين، سنة (١٩٢٦م). لقد وجد الباحث أنه من الضروري التنبيه إلى الأهمية التاريخية لمقال مظهر كونه يمثل مرحلة مبكرة من مراحل دراسة جابر في العالم العربي، ينبغي للمشتغلين بالعلوم العربية الإسلامية، والعقلية منها بخاصة، أنْ يقفوا عندها إذا ما أرادوا متابعة التطور الذي طرأ على كيفية دراسة جابر في الكتابات المعاصرة عربية كانت أم إسلامية أم استشراقية. لقد أعاد الباحث في عمله هذا عرض أهم الفِكَر الرئيسة التي وردت في مقال مظهر، والتي جاءت في سياق الحديث عن ماهية جابر التاريخية، وحياته، وأعماله، وكتابه في "السموم"، وأخيراً صلته بالإمام الشيعي السادس أبي عبدالله جعفر بن محمَّد المعروف بجعفر الصادق (ت ١٤٨هـ/٧٦٥م)، وهي المحاور الخمس التي يتألف منها مقال مظهر، ثم أخضعها للنقد والتحليل والمقارنة، مبيِّناً – قدر الإمكان - مواطن ضعفها وقوتها، ليعرض في النهاية خلاصة تتضمَّن أهم الاستنتاجات التي توصل إليها من خلال بحثه. لقد عرَّف مظهر بجابر ونبَّه إلى اختلاف الآراء بشأنه، وحثَّ على التأمل والنظر في ماهيَّته التاريخية، وعَرَضَ آراءً مختلفة عن حياته، رفدها بأحدث الآراء الاستشراقية، وزوَّدنا بثَبَت يمكن عَدُّهُ أقدم ثَبَت عربي معاصر بمؤلَّفات جابر المطبوعة، والمترجمة، والمخطوطة.
Naturschutz als Einfallstor
Authors: Gläsel Astrid , Buzogány Aron
Published: June 2023

Dass die Neue Rechte sich mit Natur befasst, ist nicht nur ideologisch, sondern auch strategisch motiviert. Ihre Aneignung bislang politisch eher links wahrgenommener Themen machen eine tiefergehende Auseinandersetzung mit diesem Phänomen unabdingbar.
Social Integration of Indonesian Ahmadiyya Community to Preserve Existence in Jambi, 2003–2013
Authors: Suhadak Totok , Sulistiyono Singgih Tri , Rochwulaningsih Yety
Published: June 2023

This study focuses on the social integration of Ahmadiyya Indonesia Community (JAI) to maintaine its Existence in Jambi in the period 2003-2013. The issue raised in this study is the ability of the JAI in Jambi to maintain its existence at a time when Ahmadiyya congregations JAI in several regions in Indonesia suffered tragic fates after their places of worship were vandalized and their members suffered acts of violence perpetrated by local residents. In this regard, this article will answer the questions of why and how JAI Jambi carried out social integration efforts in order to maintain its existence. Issues that were subject of this study are the growth of JAI in Jambi from 2003-2013 and the social integration of JAI in Jambi to maintain its existence.
How the Public in the US Responded to Javanese and Balinese Performing Arts?
Authors: Mufidah Rafngi , Puguh Dhanang Respati , Sulistiyono Singgih Tri
Published: June 2023

After declared independent, Indonesia had to deal with the question of its national identity. It was pertaining to the debate on the national culture, particularly arts. As Indonesia had diverse traditional arts, the debate was a dilemma. Many people disagreed if the traditional arts became the national identity. Meanwhile, Indonesian traditional arts, especially Javanese and Balinese ones, had been appreciated abroad. During Sukarno's regime, Indonesia sent several art missions to present itself to the world. They performed mostly traditional arts from several regions, including Java and Bali. By employing the historical method, this study aims to discuss Javanese and Balinese performing arts shows in the United States. It is of importance that from 1950s to 1960s, Indonesia had to adapt to the Cold War, which forced the developing countries to choose the Western or Eastern bloc in their foreign policy. Until the beginning of the 1960s, Indonesia tended to be with the Eastern bloc. Subsequently, there was a tendency to be with the other bloc. Therefore, in this article the response to the Javanese and Balinese performing arts shows in the US after two eras was analyze.
Science and Technology Development in Dutch East Indies
Authors: Akbar Maulana , Handayani Tri
Published: June 2023

This article describes the long history of the development of science and technology in Indonesia under Dutch East Indies Administration. This study views at how education and science and technology policies in together create the development of the contributions of researcher in research institutions. The study uses a convergent model triangulation which is a mixed method in which the qualitative use the archive to find comprehensive traces taken through written sources, quantitative method and bibliometric to show how research networks are formed in producing research from 1849 until 1940, especially on research topics. This study collects data from 201 scientific articles from Scopus database to obtain information about the trends of Dutch East Indies scientific publication. The findings of this study are after ethical politics in the beginning of 21 century, colonial government failed to provide more inclusive education system for all groups. Therefore, the scientist who contributed are mainly from European group and small contribution of Indonesian in the medical field. In the national context, there were an incline number of scientific publications after 1920s that is contributed from the established a wide range of government research and development institutions the decades before. After the colonial government ended in 1941, these advantages became the initial foundation of science and technolgy ecosystem in Republic of Indonesian Government.
Remnants of the Dutch Infrastructure in Banda Aceh During the Independence Revolution
Authors: Kamza Muhjam , Fadillah Farhan , Yusrizal M
Published: June 2023

The feud between the Dutch and Indonesia again peaked after Indonesiaproclaimed independence on August 17, 1945. War broke out in almost everyregion in Indonesia, Aceh was one of them. The basis of the hatred of the Acehnesetowards the Dutch which grew under the spirit of jihad fisabilillah [war in the wayof Allah] made the Veranda of Mecca was never negligent in opposing the Dutchcompany. Uniquely, the prolonged war that erupted in Aceh did not affect theDutch heritage buildings in Banda Aceh as the epicenter of the resistance. Thisstudy examines the function of the infrastructure of the Dutch colonial remains inBanda Aceh during the Indonesian Independence Revolution. The historicalresearch method is emphasized on utilizing primary sources in the form essayscompiled by historical actors and witnesses who lived during the independencerevolution, as well as Dutch documents in the form of photographs and maps.According to the result, the Dutch heritage infrastructure in Banda Aceh duringthe independence revolution did not find any damage caused by war and wasused for various revolutionary purposes. These buildings are generally used asthe initial function and some of them are used according to the revolutionary war.However, the practice of vandalism in the form of crossing out and pastinginformation dissemination stickers often took place in the buildings at that time.
Venereal Diseases Treatment for Merauke’s Marind (Marind-Anim) Tribe in the Dutch Colonial Period
Authors: Sinaga Rosmaida , Lubis Hafnita Sari Dewi , Tanjung Yushar , Simangunsong Lister Eva
Published: June 2023

This article provides some proofs that influenced the increasing number ofMarind-Anim people who suffering from venereal diseases. It also providesfactual efforts that had been done by the colonial government as well as Catholicmissionaries in Merauke to overcome this problem. This study applies historicalmethods with four stages: heuristics, verification (internal and external criticism),interpretation/explanation and historiography. Primary sources obtained fromNational Archives of the Republic of Indonesia i.e., Memorie van Overgave van hetBestuur over de Afdeeling Zuid Nieuw Guinea; letter of the Minister of Colonies to theGovernor General of the Dutch East Indies; Report of Assistant Resident ZuidAfdeeling Nieuw Guinea to the Director of Government; and official printed sources,e.g., Volkstelling 1930. Michel Foucault's power relations theory is used to analyzethe causes of venereal disease in the Marind Tribe. The results shows that the causeof the increasing number patients who had venereal disease in the Marind tribe,Merauke, was related to their traditional understanding which legalized free sexand deviant sexual activities in the Marind tribe. The imbalanced power relationsbetween men and their wives and between men and adolescence men causingvenereal diseases and sexual perversions in the Marind Tribe. The strategyimplemented by the colonial government was to involve Catholic missionarieswho were trusted to overcome the disease by building a housing model that canonly be occupied by nuclear families who are not infected with venereal diseases.The colonial government demolished men’s houses because there werepossibilities of homosexual intercourses which become one of the causes ofvenereal disease among the Marind Tribe. In addition, the government requiredthe cenderawasih bird hunterers to have their genital health checked as a huntingpermit. The government built hospitals and clinics and invented doctors whospecialize in venereal disease to treat the patients. These strategies has succeededin treating and eradicating venereal diseases among the Marind Tribe.
Karandu (Gong): History, Functions, and Symbols in the Life of the Tolaki People in 17th -20th Century Southeast Sulawesi
Authors: Marhadi Akhmad , Syahrun Syahrun , Melamba Basrin , Marwati Marwati , Hayari Hayari
Published: June 2023

By applying the historical method, this study aims to explain the history of the development of the gong (karandu) in Southeast Sulawesi and how the gong changes its function and symbol. The karandu entry into Tolaki estimated about the 13th century AD, originated from Java (Majapahit) and then experienced development during the Wolio kingdom. Furthermore, the acquisition of karandu occurred between the 16th and 20th centuries from outside traders as well as through shipping and trade with the natives. Gongs at that time were used as royal and confidential treasures of high value, art, ceremonies, social status, and many more. The gong evolved to communicate in particular situations, such as codes or signs of danger, meetings, grief, etc. The function of adat as a customary object in the moruhu owuku/ mooli anakia custom (buying nobility). The traditional object in marriage was called tawa-tawa sara (traditional gong), then replaced with money (nililima/ nilungga). The religious function was used when the Mokoweadeath ceremony was beaten when death occurs until the body was delivered to the cemetery. This function remained limited to the descendants of the nobility, the rich, or those with positions. In the past, gongs had an economic role with high prices and values as a criterion of prosperity. Several symbols were contained in the gong: social status, classic, unity, religious, and communication. Nowadays, they are no longer considered valuable objects.
Partial synonymy of terms: Diverse labels for, and interpretations of, light verb constructions
Authors: Hrenek Éva
Published: June 2023

The point of departure of this paper is the hypothesis that, by examining the various labels used for the verbal expressions (also) known as light verb constructions (e.g., periphrastic constructions, pleonastic expressions, semi-compositional constructions), it is possible to pinpoint the features that the various approaches dealing with that particular category and that phenomenon interpret as definitive, essential specificities of the linguistic units in question (cf. 2.1). In addition, the exploration of the differences across categories referred to by terms that are synonymous (at least in some of their uses) might contribute to outlining the features of prototypical and non-prototypical light verb constructions, and refining the systematization of the above-mentioned expressions. In this article, I will first review the general characteristics of denomination (2.1), and those of terminology formation (2.2). After that, I will briefly sketch the approaches typically connected to the terms that are occasionally used synonymously with the term light verb construction (3). Then, on the basis of the intersection of the different approaches, I will outline a definition of light verb constructions that can currently be regarded as being the most general and accepted (4). Finally, combining several views found in the literature, I will attempt a prototype-based approach to the construction type under discussion and determine the features of prototypical light verb constructions (5).
Review of Koutny, Stria, Farris, Michael (eds.) 2020: The role of languages in intercultural communication / Rolo de lingvoj en interkultura komunikado / Rola języków w komunikacji międzykulturowej. Poznań: Rys
Authors: Fortes Fabio
Published: June 2023

Intercultural exchange is undoubtedly a fact of our time. Over the last few decades, globalisation has enabled people from various parts of the world to interact for various purposes, from tourism to business, from education to international politics, from people working abroad to war refugees finding a new home. This trend was further accentuated after the 2020 pandemic, which made distance on-line communication popular and accessible on a very large scale. Despite the bright side of this phenomenon, language remains an issue (not to say a barrier) for intercultural communication.
Konferenzbericht: 32. Jahrestagung der Gesellschaft für Interlinguistik e. V., Berlin, 18.–20.11.2022
Authors: Brosch Cyril Robert
Published: June 2023

Berlin-Brandenburgische Akademie der Wissenschaften Jägerstraße 22/23 , 10117 Berlin.
Application of non‐invasive bioreactance to assess hemodynamic function in patients with hypertrophic cardiomyopathy
Authors: Okwose Nduka Charles , Fuller Amy S. , Alyahya Alaa I. , Charman Sarah J. , Eggett Christopher , Luke Peter , MacGowan Guy A. , Jakovljevic Djordje G.
Published: June 2023

Non‐invasive technologies have become popular for the clinical evaluation of cardiac function. The present study evaluated hemodynamic response to cardiopulmonary exercise stress testing using bioreactance technology in patients with hypertrophic cardiomyopathy. The study included 29 patients with HCM (age 55 ± 15 years; 28% female) and 12 age (55 ± 14 years), and gender matched (25% female) healthy controls. All participants underwent maximal graded cardiopulmonary exercise stress testing with simultaneous non‐invasive hemodynamic bioreactance and gas exchange. At rest, patients with HCM demonstrated significantly lower cardiac output (4.1 ± 1.3 vs. 6.1 ± 1.2 L/min; p < 0.001), stroke volume (61.5 ± 20.8 vs. 89.5 ± 19.8 mL/beat; p < 0.001), and cardiac power output (0.97 ± 0.3 vs. 1.4 ± 0.3watt; p < 0.001), compared to controls. At peak exercise, the following hemodynamic and metabolic variables were lower in HCM patients that is, heart rate (118 ± 29 vs. 156 ± 20 beats/min; p < 0.001), cardiac output (15.5 ± 5.8 vs. 20.5 ± 4.7 L/min; p = 0.017), cardiac power output (4.3 ± 1.6 vs. 5.9 ± 1.8 watts; p = 0.017), mean arterial blood pressure (126 ± 11 vs. 134 ± 10 mmHg; p = 0.039), and oxygen consumption (18.3 ± 6.0 vs. 30.5 ± 8.3 mL/kg/min; p < 0.001), respectively. Peak arteriovenous oxygen difference and stroke volume were not significantly different between HCM patients and healthy controls (11.2 ± 6.4 vs. 11.9 ± 3.1 mL/100 mL, p = 0.37 and 131 ± 50.6 vs. 132 ± 41.9 mL/beat, p = 0.76). There was a moderate positive relationship between peak oxygen consumption and peak heart rate (r = 0.67, p < 0.001), and arteriovenous oxygen difference (r = 0.59, p = 0.001). Functional capacity is significantly reduced in patients with HCM primarily due to diminished central (cardiac) rather than peripheral factors. Application of non‐invasive hemodynamic assessment may improve understanding of the pathophysiology and explain mechanisms of exercise intolerance in hypertrophic cardiomyopathy.
Acute effects of a single neurodynamic mobilization session on range of motion and H‐reflex in asymptomatic young subjects: A controlled study
Authors: Cancela Álvaro , Arias Pablo , Rodríguez‐Romero Beatriz , Chouza‐Insua Marcelo , Cudeiro Javier
Published: June 2023

Neurodynamic techniques have yielded good clinical results in the treatment of various pathologies. The objective of this study is to examine the short‐term effects of neurodynamic techniques of the sciatic nerve on hip ROM (range of motion) and on the amplitude and latency of the soleus H‐reflex and M‐waves, in young asymptomatic subjects. In a double‐blind controlled trial design, 60 young asymptomatic participants were randomly assigned into six groups with different levels of manipulation of the sciatic nerve. The passive straight leg raise test was used to evaluate the hip ROM amplitude. All evaluations were performed before, 1 min after, and 30 min after intervention. For each time‐point, spinal and muscle excitability were also tested. ROM increased in all groups, but none of the treatment groups had superior effects than the group with no treatment. This means that ROM testing maneuvers increased ROM amplitude, with no add‐on effect of the proposed neurodynamic techniques. Neurophysiological responses changed similarly in all groups, showing that the aftereffects were not intervention‐specific. We observed a significant negative association between the change in limb temperature and the change in latencies of all potentials. ROM‐testing procedures performed repeatedly increase ROM amplitude. This observation should be considered when evaluating the aftereffects of therapeutic interventions on ROM amplitude. None of the explored neurodynamic techniques produced acute aftereffects on hip ROM amplitude, spinal or muscle excitability different to the induced by the ROM testing maneuver.
Characteristics and purification of Himalayan salt by high temperature melting
Authors: Deng Zhigan , Huang Xing , Wei Chang , Li Xingbin , Li Minting , Luo Xingguo
Published: June 2023

Himalayan rock salt contains a variety of minerals and trace elements, which is conducive to human health. The solutions of black rock salt and rose salt are alkaline, and the content of water insoluble matter is 0.34 and 0.083%, respectively. The element composition of water insoluble matter in rock salt is determined and analyzed. It is found that the main component of two kinds of rock salt water insoluble matter is soil. Due to the presence of water insoluble matter in rock salt, according to the different specific gravity of molten sodium chloride and insoluble matter, rock salt was purified by high-temperature melting method. Rose salt is mainly studied during purification. The results showed that the content of insoluble matter in rose salt decreased from 0.083 to 0.0024% after holding at 950°C for 40 min; the contents of arsenic, barium, and lead decreased to 0.0032, 0.61, and 0.21 mg·kg−1, respectively; the content of sodium increased to 39.24%, the contents of calcium, magnesium, and iron reached to 2,200, 855, and 1.31 mg·kg−1, respectively.
Energy optimization and neural-based dynamic analysis of integrated multiple stage evaporator
Authors: Pati Smitarani , Arya Raj Kumar , Kumar Rahul , Verma Om Prakash
Published: June 2023

Minimizing energy consumption is often a grave challenge in many industrial energy-intensive process units such as Multiple Stage Evaporator (MSE). Integration of Energy Reduction Schemes (ERSs) is a common technique to resume a countable amount of energy. Hence, the present work proposes a hybrid (h-) ERSs integrated MSE placed in the paper industry, used to increase the solid content of the black liquor. The h-ERSs Integrated MSE comprises several ERSs such as Thermo-Vapor Compressor, Steam-, Feed-split, and Feed Preheater to improve the energy efficiency significantly, and its energy performance is compared with base (b-) MSE. For this purpose, nonlinear mathematical models have been developed and transformed into a constrained optimization problem to search for the optimum energy efficiency obtained as Steam Economy (SE). A state-of-art metaheuristic approach, Equilibrium Optimizer (EO), along with some well-acquainted solution approaches (Interior Point OPTimizer, Interior Point Method, and Particle Swarm Optimization) has been simulated in different platforms to estimate the maximum SE to check their competitiveness for this industrial optimization problem. It is observed that EO outperformed all the algorithms with a 66 % higher SE for h-MSE than b-MSE. Eventually, the steady state parameters are applied as the initial conditions to analyze the nonlinear enthalpy dynamics of the b-and h-MSE. A neural base solution has been adopted to rigorously study the open-loop process dynamics that meet the desired product quality.
MODELIO „NUO ŪKIO IKI MOKYKLOS“ KŪRIMO PRIELAIDOS KLAIPĖDOS REGIONE: ŪKININKŲ ĮTRAUKIMO PERSPEKTYVA
Authors: Melnikova Julija , Dailidienė Inga , Grigaliūnienė Simona , Stonkė Eglė
Published: June 2023

The article analyses the prospects for small and medium-size farms relating to the development of the ‘From Farm to School’ model in the Klaipėda region. The research aimed to reveal the possibilities for involving farmers in the Klaipėda region in cooperation with educational institutions in order to provide them with farm products/services. Questions relevant to the study were discussed during a focused group discussion with representatives of small and medium-size farms in the Klaipėda region: Are farmers interested in providing services and products to educational institutions? How do they evaluate the public procurement system? What are the possible cooperation opportunities and obstacles? etc. The results show that the needs and expectations for cooperation between Klaipėda region farmers, municipal employees and educational institutions as buyers of services basically coincide. The participants in the research agreed that the food from local growers is good, and they would like children to be fed quality food from local farms in schools. However, the results of the study assumed the insufficient literacy of small and medium-size farmers in order to effectively develop cooperation with educational institutions. Therefore, the article aims to raise awareness of representatives of small and medium-size farms and all interested groups about the ‘From Farm to School’ model, which could have an impact on the better involvement of farmers, and strengthen the connection between local farming communities and educational institutions. Better awareness could help to develop targeted actions of interested parties in order to shorten food supply chains, improve the quality of food in school meals, and promote the supply of products from small and medium-size farms to educational institutions in the Klaipėda region. The research also aims to contribute to the goals of the national Sustainable Development Strategy, by developing knowledge on how it is possible to preserve or restore natural ecosystems with the help of the activities and services of small and medium-size farms.
SVEIKATOS PRIEŽIŪROS SPECIALISTŲ KVALIFIKACIJOS TOBULINIMO POREIKIAI IR YPATUMAI
Authors: Tolutiene Gitana , Rauckienė-Michaelsson Alona , Raugelė Saulius
Published: June 2023

The professional development of health-care workers is a key prerequisite for professional success, and its effectiveness contributes to the quality of health-care services at any level of health-care institution. Health-care professionals face constant changes, as a challenge to adapt to the competitive environment around them. This makes it important to ensure that health-care workers have effective training to meet their professional development needs. Thus, the aim of this study is to analyse the theoretical assumptions of professional development, and to reveal the attitudes of health-care professionals towards the needs and specifics of professional development. The study has indicated that the professional development for health-care workers is result-oriented, yet of insufficient quality, with organisational, financial and other problems. It has been found that the planning and implementation of professional development for health-care professionals is subject to specific requirements. The combination of these requirements and the way they are evolving imply that the needs and specifics of health-care professionals in the field of professional development need to be addressed beyond doubt.
VISUMINIO VOKALO TECHNIKOS TAIKYMO TEATRE GALIMYBĖS: LAISVOSIOS VOKALINĖS IMPROVIZACIJOS KONTEKSTAS
Authors: Dirgėlaitė Indrė
Published: June 2023

Acting is inseparable from the art of improvisation; it is an all-encompassing and holistic context that requires not only acting skills, but also relevant personality traits, a virtuoso mastery of techniques of expression, psychosocial resilience, and most importantly, unique and authentic expression. It is useful for an actor to be able to choose the necessary vocal techniques and apply them in performances of various kinds, to various roles, including musical roles and improvisation. It is important to be able to integrate the most progressive vocal techniques in the work, and to understand the perspective of using methods and experimenting without losing one’s individuality, which includes all styles. The article presents the Complete Vocal Technique (CVT), which covers all styles from Classical singing to hard rock, provides the opportunity to experiment with timbres and vocal effects, and allows for the application of voice techniques in speech, based on physiology and anatomy. The study and its results are presented in order to integrate this method into theatrical activities.
DIFFICULTIES FOR CASE MANAGERS WORKING WITH FAMILIES FACING SOCIAL RISK
Authors: Karasevičiūtė Salomėja
Published: June 2023

Social work has its roots in life itself. The profession of social worker is a creative combination of knowledge, values and skills. In recent years, social work with families facing social risk has received more and more attention in the country, and it can be said that social work with these families has become one of the priority areas. The article discusses the difficulties experienced by case managers when working with families facing social risk. The analysis of the problems faced by the case managers will help to improve the quality of social work, and, accordingly, to develop and expand social services for families facing social risk. Four case managers participated in the study. The results of the study revealed that a common phenomenon in families facing social risk by not having a job and not looking for one is low self-esteem. Many families facing social risk live in poverty, and this determines their further life, development and improvement. The study revealed that case managers working with families facing social risk had the following difficulties: alcoholism, a lack of social skills, violence against children, neglect of children, and lack of motivation. A close, trusting relationship between case managers and families improves the quality of the services provided, and helps to address the problems faced by the family more effectively. Case managers empower the family to be proactive in dealing with difficulties. Cooperation enables families to meet their needs for security, self-esteem and social support.
A review on recycling ash derived from Elaeis guineensis by-product
Authors: Ooi Zhong Xian , Ismail Hanafi , Abu Bakar Azhar , Teoh Yi Peng
Published: June 2023

Oil palm (Elaeis guineensis) ash is defined as the waste generated after the combustion of oil palm biomass. Malaysia is one of the world’s largest producers and exporter of palm oil in the world, and there is approximately 4 million tonnes of oil palm ash generated annually. It is estimated that the amount of oil palm ash will keep increasing due to the high demand for palm oil globally. Normally, oil palm ash is disposed without any beneficial economic return value. The awareness of this environmental crisis has increased significantly over the past few years. With the evolution of ash utilization strategies, interest in oil palm ash in various research fields has grown. Through the effort of researchers and information available, the properties of the resulting materials are affected by the percentage of substitution and particle size of the oil palm ash. The major challenges in utilizing oil palm ash are discussed in this paper, as are the beneficial effects, which can include reducing the negative environmental impact and the product cost. Although the recycling of oil palm ash is still a new focus of interest, the main thrust of waste management in Malaysia will continue to focus on this kind of research and will attempt to solve the problem of disposal of the ash as well.
Structural and functional characteristics of phytoplankton, algal mats, detritus and water quality under main abiotic factors in urban ponds (case study of urban settlement Hostomel, Bucha District, Kyiv Region, Ukraine). Report ІI. Quantitative indicators, dominant complexes of phytoplankton, detritus and water quality of urban ponds
Authors:   Institute of Hydrobiology of the NAS of Ukraine, 12 Prosp. Heroyiv Stalingrada, Kyiv 04210, Ukraine, Shcherbak V.I. , Semeniuk N.Ye. ,   Institute of Hydrobiology of the NAS of Ukraine, 12 Prosp. Heroyiv Stalingrada, Kyiv 04210, Ukraine
Published: June 2023

The paper deals with phytoplankton quantitative indicators and dominant complex structure, and dimensional and morphological characteristics of detritus particles in the ponds of Hostomel urban settlement. Water quality has been assessed according to phytoplankton characteristics. The phytoplankton abundance made up 2648.0–113675.0 thousand cells  dm–3, and it was mainly formed by Cyanobacteria. The biomass varied within 3.72–16.53 g  m–3, which is indicative of eutrophic waters. The biomass was dominated by Euglenozoa, Miozoa and Bacillariophyta. The dominant complex according to phytoplankton abundance included small-celled Cyanobacteria, according to biomass – large-celled Euglenozoa, Miozoa and Bacillariophyta with a certain share of Cyanobacteria. Different structures of dominant complexes according to abundance and biomass is an important adaptation mechanism of urban ponds phytoplankton. Phytoplankton’s high primary productivity completely fulfils energetic and trophic demands of aquatic organisms at higher trophic levels, and the unconsumed algal biomass is decomposed and transferred to the water column in the form of organic detritus. The organic detritus particles can be ranged into four classes – from minimal < 30 mcm to maximal > 101 mcm, whose biomass can reach 57.60–62.80 mg  dm–3. It indicates that this biological component is very important in forming energy flow, matter circulation and trophic relations. Water quality assessment according to phytoplankton saprobiological characteristics has shown that χ–ο-saprobic and β-mesosaprobic organisms prevailed in the ponds under study. So, the water bodies can be classified within the range “very clean”–“clean” and “moderately polluted” waters. Unlike most urban ponds, the pond network of Hostomel can be considered a quite safe recreation zone from the ecological point of view and is an attractive green space within the urban landscape.
Social dialogue and labor sphere of Ukraine under the conditions of marital law, european integration and digitalization: problems and prospects of post-war recovery
Authors:   Institute of Industrial Economics of the NAS of Ukraine, Pankova Oksana , Kasperovich Olexandr ,   Institute of Industrial Economics of the NAS of Ukraine
Published: June 2023

The authors of the article defined a set of problems in the labor sphere and the system of social dialogue under the conditions of the synergistic influence of the following factors: 1) digitalization (world trend), 2) full-scale armed aggression; 3) the impact of chronically unresolved internal problems, accumulated from 2014 to 2022; 4) the Euro-integrational vector of Ukrainian development with the intensification of this vector after Ukraine acquires the status of a candidate country for joining the European Union (2022). The authors have revealed a tendency towards the rapid activation of attention to the problems of social dialogue, readiness for changes in the current period on the part of the top management of the state, social partners and their joint representative bodies in connection with the processes of forced European integration. The article contains a thorough analysis of ILO documents regarding the assessment of the state and losses of the labor sphere as a result of full-scale armed aggression, as well as a recommendations on achieving the quality criteria of the system of social dialogue. The role of social dialogue in ensuring the stability of the labor sphere of Ukraine in the current conditions is revealed, which is defined by the need for a radical renewal of the system of interaction of social dialogue subjects, the restoration of the work of a joint representative body at the national level - the National Tripartite Socio-Economic Council, respectively, territorial tripartite socio-economic councils, active coordinated decisions and actions by social partners regarding the modernization of the current model of social dialogue in Ukraine. The updated model must meet the basic European requirements, be organically integrated into the system of post-war recovery of the social and labor sphere according to the ILO principle 'build back better'. The need to involve digital resources and possibilities for prospects of the development of the social dialogue system through its renewal on a modern technological network-digital basis is substantiated (author's idea). The practical implementation of the updated system of social dialogue becomes the basis for the creation of an information and communication platform for the interaction of partners at the inter-state and intra-state levels for the implementation of strategic decisions to ensure the stability and post-war recovery of the labor sphere, the economy and the country as a whole, in order to achieve the defined European integration benchmarks.
NEUROENDOCRINE PEPTIDES IN THE PATHOGENESIS OF COLORECTAL CARCINOMA
Authors: Ramírez-Perdomo A. , Márquez-Barrios G. , Gutiérrez L.D. , Parra-Medina R.
Published: June 2023

Colorectal carcinoma (CRC) is the third most frequent neoplasm worldwide and the second leading cause of mortality. Neuroendocrine peptides such as glucagon, bombesin, somatostatin, cholecystokinin, and gastrin as well as growth factors such as platelet-derived growth factor, epidermal growth factor, insulin-like growth factor, and fibroblast growth factor have been postulated as being involved in carcinogenesis. The fact that these neuroendocrine peptides are involved in the development of CRC through the activation of growth factors that stimulate a series of molecular pathways that activate oncogenic signaling mechanisms is emphasized in this review. Peptides such as CCK1, serotonin, and bombesin have been found to be over-expressed in human tumor tissues. Meanwhile, the expression of peptides such as GLP2 has been seen mainly in murine models. The information contained in this review provides a better understanding of the role these peptides play in the pathogenesis of CRC for basic and clinical science studies.