bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Planting Density and Nitrogen Fertilization on the Growth of Forage Rice in Reclaimed and General Paddy Fields
Authors: Jang Yeongmi , Sharavdorj Khulan , Ahn Youngjik , Cho Jinwoong
Published: November 2023

The purpose of this study is to identify the different effects exerted by planting density and nitrogen fertilization on high-salinity Reclaimed Paddy Fields(RPF) and General Paddy Fields(GPF), and to find the amount of fertilization and the planting density suitable for the growth of forage rice in each paddy field. In both experimental locations, there was no significant change in the soil due to N treatment, but in the case of RPF, electrical conductivity(EC) decreased significantly from more than 5dS/m to up to 2.87dS/m during the yellow ripe stage due to the influence of floods and concentrated precipitation on the fields. In all soils, as both the amount of N treatment and the planting density increased, there was a proportional relationship in which the number of tillers and the dry weight also increased, with the occurrence of lodging also being increased. The dry weight, as expected, was 1.5 times higher at a planting distance of 10 cm, rather than 16 cm. In addition, in both locations N treatment led to an increase in the dry weight, but when N treatment reached 400kg/ha (2.0), the dry weight decreased instead. Moreover, although there was no clear difference in feed value according to N treatment, in RPF, neutral detergent fiber(NDF) was higher than 60%, RFV was less than 98, and TDN was also low, confirming that the quality of rice was higher in GPF.
Myocastor coypus: A Health Status Update in Northern Italy
Authors: Nicoletti Arturo , Pregel Paola , Cucuzza Laura Starvaggi , Bollo Enrico , Scaglione Frine Eleonora
Published: November 2023

Myocastor coypus is a pest animal present in Africa, Europe, North America, and Asia that causes agricultural and ecological damages. Moreover, it has to be considered as a potential risk for public health. Forty-four Nutrias from the “Parco Naturale La Mandria” (Piedmont region, Northwest Italy) have been analysed. A complete necropsy and a whole histological evaluation of liver, kidney and lung have been carried out on all the animals. Moreover, the positivity to Hepatitis E Virus (HEV), Encephalomyocarditis virus (EMCV), Francisella spp., Toxoplasma gondii and Neospora caninum have been investigated. None of the animal resulted positive for HEV, EMCV, Francisella spp. or Neospora caninum. Two animals tested positive for Toxoplasma gondii. A high presence of histological lesions has been identified in different organs, suggesting that lesions could be induced by different pathogens. As previously reported, Nutria can act as a host for several pathogens, including important agents for human and animal health, and surveillance is necessary, to fully understand the biological role and the importance of coypu as a disease reservoir in our country.
Prediction Equation for Sedimentation Upstream Reservoir of the Weir with Numerical and Experimental Approaches
Authors: Ahn Jungkyu , Song Chang Geun , Park Sung Won
Published: November 2023

In this study, a new empirical equation was established to predict the sedimentation volume resulting from the construction of a multipurpose weir or low-head dam. The study employed a one-dimensional numerical model (STAFF) to investigate the key parameters affecting sedimentation volume. Short-term predictions were conducted through laboratory experiments with movable bed, and the results indicated that dimensionless unit stream power and the Shields parameter exhibited the most significant correlation with dimensionless deposition volume. Using a multiple regression approach, an empirical equation was formulated and validated for predicting sedimentation in the upstream reservoir of the weir.
Nanostructural Characterization of Luminescent Polyvinyl Alcohol / Graphene Quantum Dots Nanocomposite Films
Authors: Elumalai Dhanumalayan , Rodríguez B. , Kovtun G. , Hidalgo P. , Méndez B. , Kalleemula S. , Joshi G. M. , Cuberes M. T.
Published: November 2023

Polyvinyl Alcohol (PVA)/ Graphene Quantum Dots (GQDs) polymer nanocomposite films have been prepared, and the relationship between their structural, thermal and nanoscale morphologi-cal properties, and their photoluminescent response, has been investigated. Although according to X-ray Diffraction (XRD), Fourier-Transform Infrared Spectroscopy (FT-IR) and Differential Thermal Analysis (DTA) the incorporation of GQDs does not significantly affect the percentage crystallinity of the PVA matrix, for a range of added GQD concentrations, Atomic Force Micros-copy (AFM) showed the formation of islands with apparent crystalline morphology on the surface of the PVA/GQD films, with GQD presumably acting as a nucleating agent for island growth. The incorporation of GQD also led to the formation of characteristic surface pores with increased stiffness and frictional contrast, according to Ultrasonic Force Microscopy (UFM) and Frictional Force Microscopy (FFM) data. The photoluminescence (PL) spectra of the films were found to de-pend both on the amount of GQD incorporated and on the film morphology. For GQD loads > 1,2wt%, a GQD-related band was observed at ~ 1650 cm-1 in FT-IR, along with an increase in the PL band at lower energy. For a load of ~2wt% GQD, the surface morphology was characterized by extended cluster aggregates with lower stiffness and friction than the surrounding matrix, and the PL signal decreased.
Diagnosing Alzheimer’s Disease and Discriminating Between Its Stages from Brain FDG PET Images Using a New Platform for Radiomic Analysis
Authors: Rasi Ramin , Guvenis Albert
Published: November 2023

Abstract: This study presents a methodological framework for AD and MCI diagnosis using radiomic analysis of 18FDG-PET imaging and conducts non-invasive predictions and in-depth analysis of AD and MCI and the associated small number of regions and features. Our methodology follows a structured process commencing with data preprocessing and labeling, facilitating segmentation through FastSurfer, a tool that efficiently segments the brain into 95 ROIs using the DKT-atlas. Subsequently, Feature extraction was carried out using PyRadiomics, calculating 120 features for each of the 95 ROIs (11,400 per image). These extracted features form the foundation of our radiomics analysis, primarily for early diagnostic purposes. In the feature selection phase, we explored a set of eight commonly employed techniques, including ANOVA, PCA, and LASSO, originating from the four main categories, namely filtered, embedded, wrapper, and hybrid methods, to identify a pertinent subset of features. Our evaluation assessed the performance of nine classification methods, such as GradientBoosting, RandomForest, and GaussianNB, in conjunction with eight feature selection techniques. The choice of feature selection method and classifiers was predicated on their ability to achieve the best area under the ROC curve with independent data. For all three predictions AD vs. CN, AD vs. MCI, and CN vs. MCI the Random Forest (RF) classifier with LASSO feature selection demonstrated the highest accuracy with an AUC of 0.976 for AD vs CN, AUC=0.917 for AD vs MCI, and AUC=0.877 for MCI vs CN. In conclusion, our RAB-PET platform enables efficient AD and MCI diagnosis from FDG-PET images using a radiomics pipeline. It also offers a general hardware and software tool for the investigation of other brain disorders.
Comparative Application of Terminal Restriction Fragment Analysis Tools to Large-Scale Genomic Assays
Authors: Abdulkina Liliia R , Agabekian Inna A , Valeeva Liia R , Kozlova Olga S. , Sharipova Margarita R. , Shakirov Eugene V
Published: November 2023

Analysis of telomere length is an important component of many studies aiming to characterize the role of telomere maintenance mechanisms in cellular lifespan, disease, or in general chromosome protection and DNA replication pathways. Several powerful methods to accurately measure telomere length from Southern blots have been developed, but their utility for large-scale genomic studies has not been previously evaluated. Here we performed comparative analysis of two recently developed programs, TeloTool and WALTER, for extracting mean telomere length values from Southern blots. Using both software packages, we measured telomere length in two extensive experimental datasets for the model plant Arabidopsis thaliana, consisting of 537 natural accessions and 65 T-DNA mutant lines in the Col-0 reference background. We report that TeloTool substantially overestimates telomere length in comparison to WALTER, especially for values over 4,500 bp. Importantly, TeloTool and WALTER-calculated telomere length values correlate the most in the 2,100-3,500 bp range, suggesting that telomeres in this size interval can be estimated by both programs equally well. We further show that genome-wide association studies using datasets from both telomere length analysis tools can detect the most significant SNP candidates equally well. However, GWAS analysis with the WALTER dataset consistently detects fewer significant SNPs than analysis with the TeloTool dataset, regardless of the GWAS method used. These results imply that telomere length data generated by WALTER may represent a more stringent approach to GWAS and SNP selection for downstream molecular screening of candidate genes. Overall, our work revealed the unanticipated impact of telomere length analysis method on the outcomes of large-scale genomic screens.
Review of Photonic RF Channelizers based on Optical Microcombs
Authors: Moss David , xu xingyuan , tan sim
Published: November 2023

In recent decades, microwave photonic channelization has developed rapidly. Characterized by low loss, high versatility, large instantaneous bandwidth, and immunity to electromagnetic interference, microwave photonic channelization techniques coincides with the requirements of modern radar and electronic warfare for receivers. The advanced microresonator-based optical frequency combs are promising platforms for the research of the photonic channelized receivers, which take full advantage of multicarrier and large bandwidth, and accelerate the integration process of microwave photonic channelized receivers. In this paper, we review the research progress and trends in microwave photonic channelization, focusing on schemes that utilize integrated microcombs. Finally, we discuss the potentials of microcomb-based RF channelization, as well as the challenges and limitations, and provide routes and perspectives for future developments in the context of on-chip silicon-based photonics.
iPSC-Derived Endothelial Cells Reveals LDLR-Dysfunction and Dysregulated Gene Expression Profiles in Familial Hypercholesterolemia
Authors: Zakharova Irina S. , Shevchenko Alexander I. , Arssan MHD Amin , Sleptcov Alexei A , Nazarenko Maria S. , Zarubin Aleksei A. , Zheltysheva Nina V. , Shevchenko Vlada A. , Tmoyan Narek A. , Saaya Shoraan B. , Ezhov Marat V. , Kukharchuk Valery V. , Parfyonova Yelena V. , Zakian Suren M.
Published: November 2023

Defects in low-density lipoprotein receptor (LDLR) are associated with familial hypercholesterolemia (FH), manifested by atherosclerosis and cardiovascular disease. Defective LDLR in hepatocytes leads to increased blood cholesterol level that damage vascular cells, especially endothelial cells, through oxidative stress and inflammation. However, the distinctions between endothelial cells from individuals with normal and defective LDLR are not yet fully comprehended. In this study, we obtained and examined endothelial derivatives of induced pluripotent stem cells (iPSC) generated previously from conditionally healthy donors and compound heterozygous FH patients carrying pathogenic LDLR alleles. In normal iPSC-derived endothelial cells (iPSC-EC), we detected the LDLR protein predominantly in its mature form, while iPSC-EC from patients with FH display reduced level of mature LDLR and show abolished low-density lipoprotein uptake. RNA-seq of iPSC-EC with mutant LDLR revealed a unique transcriptome profile comprising downregulated genes related to monocarboxylic acid transport, exocytosis and cell adhesion, as well as upregulated signaling pathways of cell secretion and leukocyte activation. Overall, these findings suggest that LDLR defects increases susceptibility of endothelial cells to inflammation and oxidative stress. This, combined with elevated extrinsic cholesterol levels, may result in accelerated endothelial dysfunction, contributing to early progression of atherosclerosis and other cardiovascular pathologies related to FH.
Development of Immersion and Oral Bivalent Nanovaccines for Streptococcosis and Columnaris Disease Prevention in Fry and Fingerling Asian Seabass (Lates calcarifer) Nursery Farms
Authors: Meachasompop Pakapon , Bunnoy Anurak , Keaswejjareansuk Wisawat , Dechbumroong Piroonrat , Namdee Katawut , Srisapoome Prapansak
Published: November 2023

In the present study, bivalent nanovaccines of S. iniae and F. covae were administered by immersion vaccination at 30 and 40 days after hatching (DAH), and the third vaccination was orally administered by feeding at 50 DAH. Five different groups were designed: group 1 was set as the control group, and groups 2-4 were vaccinated using the same protocols. ELISA revealed that the levels of total IgM and specific IgM to S. iniae, and F. covae were significantly elevated in groups 2-4 at 10, 20, and 30 days after vaccination (DAV). A qRT‒PCR analysis of immune-related genes revealed significantly higher IgT expression in the vaccinated groups compared with the control group, as revealed by 44-100-fold changes in the vaccinated groups compared with the control (p < 0.001) at every tested time point after vaccination. All vaccinated groups expressed IgM, MHCIIα and TCRα at significantly higher levels than the control group at 10 and/or 20 DAV (p < 0.05). In the S. iniae challenge tests, the survival of vaccinated groups 2-4 ranged from 62.15 ± 2.11 to 75.70 ± 3.36%, which significantly differed from that of the control group (44.44 ± 1.92%). Similarly, all vaccinated groups showed higher survival rates of 68.89 ± 3.85 to 77.78 ± 5.09% during F. covae challenge than the control groups (50.00 ± 3.33%) (p < 0.05).
Airport Pavement Maintenance Decision-Making System with Condition Cases Optimization
Authors: Roh Seunghyun , Lee Jinwoo , Urbino Ivan Jan , Lin Wuguang , Cho Yoonho
Published: November 2023

The rapid growth of the aviation industry has progressively heightened the importance of airport maintenance management. There is an increasing need for a comprehensive system that considers the diverse requirements of various stakeholders. Existing research has primarily focused on the technological advancements of optimization models, with limited applicability in practice. In this study, we introduce the Condition Cases Optimization (CCO) to address these limitations while incorporating multi-facility and multi-year network optimization models. We developed condition index, Serviceability Level, integrated assessment indices and performance models for decision-making criteria. We categorize conditions into three classes and propose a practical decision-making strategy that can flexibly adapt to budget constraints. Sensitivity analysis highlights the impact of initial budget, maintenance methods, costs, and thresholds on decision outcomes. Through a case study we validate the effectiveness and practicality of the CCO method as an efficient decision-making tool.
Daily scale Prediction of Arctic Sea Ice Concentration Based on Recurrent Neural Network Models
Authors: Feng Juanjuan , Li Jia , Zhong Wenjie , Wu Junhui , Li Zhiqiang , Kong Lingshuai , Guo Lei
Published: November 2023

Arctic sea ice prediction holds significant importance for facilitating Arctic route planning, optimizing fisheries management, and advancing the field of sea ice dynamics research. While various deep learning models have been developed for sea ice prediction, they predominantly operate at the seasonal or sub-seasonal scale, often focusing on localized areas, and few cater to full-region daily scale prediction. This study introduces the use of spatiotemporal sequence data prediction models, namely, the convolutional LSTM (ConvLSTM) and predictive recurrent neural network (PredRNN), for the prediction of sea ice concentration (SIC). Our analysis reveals that, when solely utilizing SIC historical data as the input, the ConvLSTM model outperforms the PredRNN model in SIC prediction. To enhance the model's capacity to capture spatiotemporal relationships between multiple variables, we expanded the range of input data types to form the ConvLSTM-multi and PredRNN-multi models. Experimental findings demonstrate that the ConvLSTM-multi model excels in assimilating the influence of reanalysis data on sea ice within the sea ice edge region, thus exhibiting superior performance in predicting daily Arctic SIC over the subsequent 10 days. Furthermore, sensitivity tests on various model parameters highlight the substantial impact of sea surface temperature and prediction date on the accuracy of daily sea ice prediction. Additionally, meteorological and oceanographic parameters primarily affect the prediction accuracy of the thin ice region at the edge of the sea ice.
Expectation and Optimal Allocations in Existential Contests of Finite, Generalized Hyperbolic-Distributed Outcomes
Authors: Vince Ralph
Published: November 2023

Financial time series and other human-driven, non-natural processes are known to exhibit fat-tailed outcome distributions. That is, such processes demonstrate a greater tendency for extreme outcomes than the normal distribution or other natural distributional processes would predict. We examine the mathematical expectation, or simply "expectation," traditionally the probability-weighted outcome, regarded since the seventeenth century as the mathematical definition of "expectation." However, when considering the "expectation" of an individual confronted with a finite sequence of outcomes, particularly existential outcomes (e.g., a trader with a limited time to perform or lose his position in a trading operation), we find this individual "expects" the median terminal outcome over those finite trials, with the classical seventeenth-century definition being the asymptotic limit as trials increase to this. Since such finite-sequence "expectations" often differ in values from the classic one, so do the optimal allocations (e.g., growth-optimal). We examine these for fat-tailed distributions. The focus is on implementation, and the techniques described can be applied to all distributional forms.
Chemical Profiles and Chemometric Analysis of Selected Leucobryum Species (Bryophyta, Leucobryaceae) from Thailand
Authors: Tiwutanon Patsakorn , Wongthet Natthawadi , Vajrodaya Srunya , Kraichak Ekaphan
Published: November 2023

Leucobryum is a moss genus that exhibits various bioactivities. However, the identification of Leucobryum species with morphology alone remains difficult. Nowadays, chemical profile analysis provides additional tools for plant classification, especially in medicinal plants. This method uses chemical similarities to identify the differences among some plants, especially for the different varieties of the same species. The objective of this study was to obtain the chemical profiles and use chemometrics to identify selected Leucobryum species found in Thailand. Lipophilic extracts from 18 samples of five taxa were analyzed with TLC and HPLC. Cluster analysis and PCA were used to investigate the similarities of the chemical profiles. PERMANOVA was performed to determine the difference among taxa. The results showed that the TLC profile could separate only the genus of the sample, while HPLC chromatograms showed separation among the Leucobryum taxa and consistent patterns within the same species. In addition, the chemical profiles of Leucobryum species were separated at the species level in PCA. The PERMANOVA showed significantly different profiles among the species (P = 0.002). Therefore, this work illustrated the potential of chemometrics as supporting evidence for species delimitation in the moss genus Leucobryum.
Bracing with Tape and Extensor Refixation of Elbow with Posterolateral Instability Due to Cubitus Varus
Authors: Sachinis Nikolaos Platon , Beitzel Knut , Moya Daniel , Gomez Diego , Koukos Christos
Published: November 2023

Case:

A 54-year-old patient had lateral ligament insufficiency due to cubitus varus from a childhood supracondylar fracture. Arthrolysis/synovectomy and at a later stage double-row extensor origin refixation and lateral ulnar collateral ligament bracing with nonabsorbent tape and anchors were performed. Follow-up at 3, 6, 12, and 24 months showed excellent Mayo Elbow Performance and Disabilities of Arm, Shoulder, and Hand Scores (24-month follow-up = 100 and 2.5, respectively).

Conclusion:

Suture tape augmentation and double-row extensor refixation in cases of lateral collateral ligament complex insufficiency due to cubitus varus may provide improved short-term functional outcomes, from the third postoperative month.
Buku Ajar Budaya Organisasi
Authors:   Universitas Muhammadiyah Sidoarjo, Sumartik Sumartik , Abadiyah Rifdah , Ubaidillah Hasan
Published: November 2023

Alhamdulillah, Puji syukur kami panjatkan kehadirat Alloh SWT atas rahmat yang diberikan sehingga dapat menyusun proposal hibah buku ajar Budaya Organisasi yang diperuntukkan bagi mahasiswa semester enam. Dalam buku ini kita diajak lebih mengenal budaya organisasi, tekhnik berkomunikasi dan faktor penunjang serta penghambat budaya organisasi yang kedepannya dapat membentuk strategi budaya organisasi dalam meningkatkan kinerja bisnis ataupun kinerja karyawan. Buku ini terdapat 11 bab, yang membahas mengenai pengertian budaya, organisasi dan kebudayaan, isu-isu dasar budaya organisasi, membangun budaya organisasi, kompetensi dalam budaya organisasi, mengubah budaya organisasi, sosialisasi budaya organisasi dan kinerja, kepemimpinan dan budaya, keanekaragaman budaya organisasi, Multi kultural budaya, Komunikasi antar budaya dan Negosiasi antar budaya.
Digital circuit for switch contact bounce analysis
Authors: Ivaniuk A. A. , Mozhejko D. O.
Published: November 2023

This article discusses the issue of studying the parameters of the bounce of electrical contacts of switches in digital systems. Digital circuits of bounce analyzer are described. The results of experimental studies of the behavior of electrical contacts of various buttons and switches are presented. It is shown that various electric switches have random and unique characteristics, which can be used to solve the problems of random numbers generating, identifying of digital devices and user’s authentication. Prototyping of the proposed circuits was carried out on Digilent ZYBO Z7-10 debug boards, digital circuits were designed in VHDL for the Xilinx Zynq-7000 FPGA chip.
Methodology for collective location fixing of observed emergencies by intersection/resection based on mobile telecomunication application with cartographic interface
Authors: Miheev A. G. , Bryljov V. D. , Gruzinov V. S. , Savel'ev M. V.
Published: November 2023

In modern higher education, it is required not only to prepare students to perform work on finished tasks in the subject area they have studied. It is also necessary to prepare students for independent activities, in which students do not work on ready-made tasks, but, on the contrary, are looking for niches in business, in which they themselves can offer in the subject area they have mastered, business-demanded solutions. This is another area of activity, which also requires development while studying at a university. It can be defined as "entrepreneurial competencies of a student." In recent years, the direction "Startup as a Diploma" has been developing, in which a university graduate protects not conditional academic work, but a real technological project with business prospects, to which the students developing it have ownership rights. The creation and maintenance of such projects changes the relationship between student and teacher, for this activity it is necessary to change the traditional teaching methodology. As a task of teachers, we decided to do the following: Find a subject area related to IT development, in which, due to recent achievements, there are opportunities for fast, technically not very complex technological solutions available to students, with the help of which you can create popular solutions. The work proposes an open source software development project, within which students can, performing tasks that are feasible for themselves, create software applications that are in demand in practice, as well as develop development strategies for related business projects. The project is dedicated to solving the problem of determining the coordinates of observed objects and phenomena based on data entered simultaneously by several users in different places using household mobile devices without using special technological equipment such as theodolites or tacheometers. The authors developed a mobile application, the value of which lies in the fact that in the public field allows you to realize the monitoring potential of the population interested in preventing unwanted or dangerous events and preventing emergency situations; professional allows you to assess the quality of the navigation signal in conditions of possible targeted interference; in the educational aspect organize training in the methods of joint fixation of objects and target designation on educational geopolygons. Currently, the project is being developed by students of the Department of Data Analysis and Machine Learning of the Financial University under the Government of the Russian Federation and the Moscow State University of Geodesy and Cartography. This paper presents a description of the project, the proposed solution architecture. References to source code repositories are given. The results of the pilot versions of the software are given.
ADMINISTRACIÓN MANCOMUNADA Y CONVOCATORIA DE LA JUNTA: ¿DIMENSIÓN ESTRICTAMENTE INTERNA?
Authors: Soler Samper Carlos
Published: November 2023

El pasado mes de julio el Tribunal Supremo sentó precedente en uno de los aspectos societarios más controvertidos, tal y como es la administración mancomunada y la convocatoria de junta, a través de su sentencia de 16 de julio de 2019, nº 424/2019 (Rec. nº 3784/2016).
Nueva tentativa de fomento y promoción del trabajo autónomo
Authors: Ugena Muñoz Sara
Published: November 2023

En España el tejido productivo está compuesto esencialmente por trabajadores por cuenta propia y por pequeñas y medianas empresas. Centrándonos en este trabajador, comúnmente denominado autónomo, y partiendo de su configuración como aquella persona natural que en nombre propio y por su cuenta y riesgo desarrolla de manera habitual una actividad empresarial, cualquier persona física, que sea mayor de edad y no se encuentre incapacitada, podrá adquirir la condición de empresario individual en el mercado y quedará sometida a un estatuto jurídico especial delimitado por el Derecho mercantil (...).
Mecanismos para solucionar un bloqueo societario en una sociedad de capital
Authors: Serrano Acitores Antonio
Published: November 2023

Las situaciones de bloqueo en las sociedades de capital suelen ocasionarse en aquellos casos en los que, por la igualdad de fuerzas en la Junta General o por la composición del órgano de administración, es imposible la adopción de acuerdos debido a las desavenencias entre sus miembros.
El valor de la información y su protección en el régimen de competencia desleal en Colombia
Authors: Quintana Cepeda Anamaría
Published: November 2023

Llama mucho la atención escuchar en los medios de comunicación los términos “sociedad de la información” y “mercado de la información”. Lo cierto es que nuestro tiempo se caracteriza por la innovación permanente en prácticamente todos los órdenes de la vida y por cuantiosas inversiones por parte de los agentes económicos para lograr el conocimiento necesario que permita el aumento de su participación en el mercado.
El Reglamento 2015/848, una regulación actualizada para el fenómeno de la insolvencia transfronteriza en la Unión Europea
Authors: Ortega Rueda José David
Published: November 2023

No es aventurado afirmar que el mercado interior encarna el epítome de la Unión Europea. Como todos sabemos, el objetivo pretendido por esta construcción jurídica no es otro que promover el desarrollo sostenible de nuestro continente desde una perspectiva social y económica. A tal fin se constituye un espacio sin fronteras interiores, integrado por los territorios de los Estados miembros, en cuyo contexto se despliega un formidable entramado de intercambios civiles y mercantiles de naturaleza transfronteriza. Ahora bien, para lograr el correcto funcionamiento de todo este sistema, es necesario articular una regulación adecuada que asegure la eficacia y eficiencia en la reclamación de créditos ya que, de otro modo, se acabaría conculcando la seguridad jurídica en el tráfico comercial europeo. Obviamente, los procedimientos de insolvencia no pueden ni deben ser una excepción pues, en última instancia, con ellos se pretende optimizar la satisfacción crediticia de una pluralidad de acreedores cuando el deudor común de todos ellos se encuentra en un determinado contexto patrimonial o financiero: la situación de insolvencia.
El nuevo régimen de retribución de los consejeros ejecutivos tras la reforma operada por la Ley 31/2014, de 3 de diciembre, por la que se modifica la Ley de Sociedades de Capital para la mejora del Gobierno Corporativo
Authors: Cortés Josefa Brenes
Published: November 2023

En el presente trabajo abordamos un tema de especial interés y relevancia, no sólo por su actualidad sino también por la dificultad que entraña: el relativo a la autonomía o no del contrato remuneratorio de los consejeros ejecutivos en relación con los estatutos y con el acuerdo de junta del artículo 217 del Real Decreto Legislativo 1/2010, de 2 de julio por el que se aprueba el Texto Refundido de la Ley de Sociedades de Capital tras la modificación operada en el régimen jurídico aplicable a la retribución de los administradores por la Ley 31/2014, de 3 de diciembre por la que se modifica la Ley de Sociedades de Capital para la reforma del Gobierno Corporativo.
Modificaciones en la Ley de Contrato de Seguro a propósito de la Ley 20/2015, de 14 de julio, de Ordenación, Supervisión y Solvencia de las entidades aseguradoras y reaseguradoras
Authors: Ortiz del Valle Mª del Carmen
Published: November 2023

Debido al papel esencial que juegan el sector financiero y, en particular, el sector asegurador en la economía, se ha justificado históricamente una mayor regulación e inter-vención pública que en otros sectores. Te-niendo en cuenta las características propias de la actividad aseguradora, ésta exige garantizar que cuando se produzca el siniestro que moti-ve el pago de la indemnización la entidad ase-guradora esté en situación de poder hacer frente a dicha obligación. Ello justifica que la ordenación y supervisión de las entidades aseguradoras por los poderes públicos resulte una materia de gran interés público, para comprobar que mantienen una situación de solvencia suficiente que les permita cumplir su objeto social. En estos términos se pronuncia el Preámbulo de la Ley 20/2015, de 14 de julio, de ordenación, supervisión y solvencia de las entidades aseguradoras y reaseguradoras (LOSSEAR).
La previsible evolución de la regulación de los contenidos digitales en el Derecho de la Unión Europea (Propuesta de Directiva 634/2015, de 9 de diciembre, sobre ciertos aspectos relativos al suministro de contenidos digitales)
Authors: Castilllo José Antonio
Published: November 2023

RESUMEN: Tras la retirada de la Propuesta CESL por la Comisión en mayo de 2015 con intención de modificarla en aras de procurar un mayor avance en el Mercado Único Digital (tal como se expresa en la comunicación titulada “Una Estrategia para el Mercado Único Digital de Europa”) se publicaron el pasado 9 de diciembre dos Propuestas de Directiva (634 y 635 /2015) y una Propuesta de Reglamento (627/2015) que inciden en dicha voluntad de avance en el Mercado Único Digital. Se trata de textos que se hayan aún en una primera fase de discusión, pero avalados por una firme voluntad por parte de la Comisión de sacarlos adelante. En este breve trabajo comentamos la incidencia que tendrá una de ellas, la Propuesta 634/2015, sobre ciertos aspectos relativos al suministro de contenidos digitales, en la vigente regulación de los mismos a través de la Directiva 2011/83 y la Ley 3/2014, de transposición de la Directiva y modificación del TRLGDCU; únicos textos en vigor hasta el momento que hacen referencia a los contenidos digitales y al contrato para el suministro de contenidos digitales.
El régimen simplificado para pequeños contribuyentes (“Monotributo”) ante la eliminación de las Sociedades de Hecho en el Derecho Tributario Argentino
Authors: Suozzi Leonel Alejandro
Published: November 2023

La consolidación del nuevo Código Civil y Comercial Argentino trajo como consecuencia variadas reformas en el ámbito del derecho comercial de ese país sin prever totalmente los colaterales efectos en otras ramas del derecho. En tal sentido, la modificación a la Ley 19.550, Ley de Sociedades Comerciales hoy denominada “Ley General de Sociedades” eliminó a las antiguas denominaciones “Sociedades Irregulares” y “Sociedades de Hecho” para pasar a regular a las sociedades no regularmente constituidas como “Sociedades de la Sección IV del capítulo I de la Ley General de Sociedades”. En este sentido, más allá de las modificaciones en materia comercial para este tipo de entidades, vale analizar el impacto en el Derecho Tributario. La Ley 26.565 que regula al Régimen Simplificado para Pequeños Contribuyentes permite una adecuada simplificación de trámites y costos pertinentes a los efectos de que pequeñas explotaciones comerciales puedan dar cumplimiento a sus obligaciones fiscales y de la seguridad social sin tener que subordinarse a las complejas estructuras y deberes destinados para grandes empresas. Ahora bien, cabe preguntarse ¿Cómo y con qué alcance debe ser regulada una sociedad que pretenda asemejarse a las antiguas “Sociedades de Hecho” considerando que dicha denominación ha sido borrada de nuestro Derecho Societario?
Las retribuciones de los directivos: a propósito de los bonus
Authors: Rodríguez Martín-Retortillo Rosa María
Published: November 2023

Los sistemas de retribución por objetivos son muy frecuentes en nuestros días, dada la flexibilidad que supone su fijación, amparada por una regulación casi ausente. A su favor se argumenta el impacto que su establecimiento causa en el rendimiento del trabajador, con el consecuente efecto dominó para la empresa, pues a priori cuanto más productivo sea, mejores serán los resultados de la misma, generando el derecho al cobro del incentivo si se alcanzan los objetivos deseados. No obstante, pese a la carencia normativa que se ha apuntado, su alcance y límites han venido marcados por los contratos de trabajo y por la jurisprudencia, dados los diversos problemas que se pueden plantear en cuanto a su determinación, pago o en los casos complejos en que su devengo se vincula a resultados de grupo.
La normalización de la aplicación de la cláusula “Rebus sic stantibus” según la jurisprudencia del Tribunal Supremo
Authors: González-Guimaraes Javier
Published: November 2023

Desde las SSTS del Pleno de la Sala de lo Civil de 17 y 18 de enero de 2013, y, posteriormente, con las SSTS de 30 de junio y 15 de octubre de 2014 y de 24 de febrero de 2015, hemos asistido a una verdadera eclosión de resoluciones judiciales que, de un modo u otro, han venido admitiendo a supuestos no tan excepcionales la cláusula “rebus sic stantibus”. Hasta entonces calificada como cláusula “peligrosa” y de “admisión cautelosa”.
Nuevo marco legal en materia de abuso de mercado
Authors: Bermúdez Madrigal Julio
Published: November 2023

El 12 de junio de 2014 se publicó en el Diario Oficial de la Unión Europea (en adelante “DOUE”) el Reglamento (UE) Nº 596/2014 del Parlamento Europeo y del Consejo de 16 de abril de 2014 sobre el abuso de mercado y por el que se derogan la Directiva 2003/6/CE, y las Directivas 2003/124/CE, 2003/125/CE y 2004/72/CE (en delante el “Reglamento”) que establece una normativa común en materia de abuso de mercado en todos los Estados miembros. Este Reglamento entró en vigor el pasado 3 de julio de 2016, si bien las disposiciones que permiten a la Comisión europea y a la Autoridad Europea de Valores y Mercados (en adelante “ESMA”) desarrollar su contenido entraron en vigor el 2 de julio de 2014.
Impugnación de acuerdos sociales mediante mecanismos societarios en caso de incumplimiento de un pacto parasocial omnilateral “Venire contra factum proprium non valet”
Authors: Saugar Koster Adriana Eugenia
Published: November 2023

Existe numerosa doctrina contradictoria en relación a la utilización de mecanismos societarios para la impugnación de acuerdos societarios en caso de incumplimiento de pactos parasociales.
Una reforma procesal de calado en materia de reclamaciones derivadas de actos anticoncurrenciales
Authors: Cohen Benchetrit Amanda
Published: November 2023

Por medio del Real Decreto-Ley 9/2017, de 26 de mayo (BOE 27 de mayo de 2017) se ha llevado a cabo en nuestro país la implementación, entre otras, de la Directiva 2014/104/UE (comúnmente conocida como la “Directiva de daños” -en adelante, la Directiva). La convalidación de este Real Decreto- Ley se acordó por el Congreso de los Diputados en su Resolución de 22 de junio de este año (BOE 30 de junio de 2017).
La figura del administrador de hecho y su incidencia en sede concursal
Authors: Armijo Pliego Ana
Published: November 2023

El artículo 133 de la LSA (Ley 26/2003, de 17 de julio) introdujo en nuestro ordenamiento jurídico la figura del administrador de hecho al regular –por primera vez- un régimen de responsabilidad para quienes ejercitan el facultadas de gestión y control sin ostentar formalmente el cargo de administrador social, actuaran como tal; si bien, el texto legal no introdujo una definición de dicho concepto.
Primeras impresiones sobre la resolución de la Sala de Competencia de la Comisión Nacional de los Mercados y de la Competencia (CNMC) de 13 de febrero de 2018 en el expediente S/DC/0579/16
Authors: Martín Baumeister Bruno
Published: November 2023

Resumen: En su resolución de 13 de febrero de 2018 la CNMC sanciona a cuatro entidades de crédito por infracción muy grave del artículo 1 de la Ley de Defensa de la Competencia (LDC) así como del artículo 1 del Tratado sobre el Funcionamiento de la Unión Europea (TFUE) por actuación concertada en la fijación de precios por encima de las condiciones de mercado en los derivados extrabursátiles utilizados como cobertura del riesgo de tipo de interés en préstamos sindicados en financiación de proyectos. La CNMC acepta que ni la fijación del precio de los tipos floor y swap ‘en condiciones mercado’ o con ‘coste cero’ ni tampoco –aunque con algunas dudas– la fijación de dichos tipos con un margen (spread) representan una conducta prohibida del apartado 1 de los artículos 1 LDC y 101 TFUE. Sin embargo, la determinación de un precio de los tipos superior al precio que hubiera derivado de su fijación en condiciones de mercado es ilícita cuando se realiza con desconocimiento de la parte financiada, lo que representa una restricción por objeto en forma de infracción única y continuada en el tiempo en el sentido del artículo 1 LDC y del artículo 101 TFUE.Palabras clave: Crédito sindicado; derivado de cobertura de tipo de interés; práctica colusoria.
El delito de administración desleal. Los administradores societarios como sujetos activos del mismo y su relación con los deberes de diligencia y lealtad.
Authors: Jiménez Crespo Luis Miguel
Published: November 2023

Este artículo tiene como objeto llevar a cabo una breve exposición sobre la relación existente entre el nuevo tipo penal de administración desleal contenido en el art. 252 del Código Penal en la  redacción dada al mismo la Ley Orgánica 1/2015, de 30 de marzo que  entró en vigor el 1 de julio de 2015 y la posibilidad de que los administradores societarios sean sujetos activos del mismo por infracción de los deberes de diligencia y lealtad tal y como han quedado definidos en la Ley de Sociedades de Capital (LSC) tras la reforma operada  por la Ley 31/2014, de 3 de diciembre por la que se modifica esta ley para la mejora del gobierno corporativo
APORTACIONES DE LA SENTENCIA DE LA SALA 1ª DEL TRIBUNAL SUPREMO DE 1 DE OCTUBRE DE 2018 EN MATERIA DE AUTOCARTERA Y ASISTENCIA FINANCIERA EN S.R.L.
Authors: Rodríguez Ruiz de Villa Daniel
Published: November 2023

La Sentencia de la Sala 1ª del Tribunal Supremo de 1 de octubre de 20181 -en adelante STS de 1 de octubre de 2018-, confirmando la Sentencia de la Sección 1ª de la Audiencia Provincial de Cáceres de 10 de septiembre de 20152 -en adelante SAP Cáceres de 10 de septiembre de 2015-, se ha ocupado de diversas cuestiones interesantes en materia de Derecho de sociedades de capital.
LA INSTRUMENTACIÓN DE UNA DEUDA PREEXISTENTE EN PAGARÉS PREVIA A LA DECLARACIÓN DE CONCURSO
Authors: Espigres Huete José Carlos
Published: November 2023

Planteamiento: ingeniería del jurista y acto concreto que se pretende rescindir.
FORMA E PROVA DEI CONTRATTI DI CESSIONE E LICENZA DI BREVETTO: NOTA A CASS. No 12971/2019
Authors: Dalla Verità Maria Sofia
Published: November 2023

La cessione e la licenza di brevetto (ma lo stesso si potrebbe dire in relazione al marchio [art. 23 CPI, art. 2573 c.c.]) sono due contratti che inspiegabilmente non vengono disciplinati né dal codice civile, né dal codice della proprietà industriale: si fa qui riferimento al trasferimento dei diritti patrimoniali legati all’invenzione e non al diritto di paternità dell’autore che, come noto, non può essere ceduto.
LA SUSTITUCIÓN DE TRABAJADORES POR ROBOTS. LA FRONTERA ENTRE LA LIBERTAD DE EMPRESA Y EL DERECHO AL TRABAJO EN LA ERA DIGITAL
Authors: Rodríguez Martín-Retortillo Rosa Mª
Published: November 2023

En este artículo se plantean los desafíos que se le presentan al Derecho del Trabajo en la era digital, con un enfoque reflexivo, que aborda tanto la dimensión empresarial como la del trabajador. Tras la reciente Sentencia del Juzgado de lo Social no 10 de Las Palmas de Gran Canaria de 23 de septiembre de 2019, que califica como improcedente el despido de una trabajadora tras sustituirla por un robot, se abre el debate acerca de los límites de la libertad de empresa frente al derecho al trabajo del empleado en el siglo XXI. Con ello se pretenden revisar cuáles son esas fronteras en este nuevo contexto tecnológico de avance imparable.
IMPACTO DE LA LEY DE APOYO A LOS EMPRENDEDORES Y A SU INTERNACIONALIZACIÓN. NUEVOS CRITERIOS DE APLICACIÓN.
Authors: Ortega Giménez Alfonso , Castellanos Cabezuelo Ángela
Published: November 2023

Hasta nueve Ministerios participan en la elaboración de uno de los proyectoslegislativos más emblemáticos del Gobierno del Presidente Rajoy (la Ley 14/2013, de 27 de septiembre, de apoyo a los Emprendedores y su Internacionalización) que revisa toda la normativa relativa al empleo y al emprendedurismo y afecta tanto al diseño de las materias en la Educación Primaria como a la política de concesión de visados de residencia del Gobierno.El conjunto de medidas que prevé la Ley pretende, entre otros, atraer inversores, emprendedores, trabajadores que efectúen movimientos intraempresariales, profesionales altamente cualificados e investigadores. Las medidas implementadas en la Ley, en definitiva, permitirán aumentar la competitividad de la economía de nuestro país, puesto que incentivará la internacionalización de las empresas.  Este articulo pretende, de una forma sencilla, ágil y con un enfoque práctico, analizar los nuevos criterios de aplicación de la Ley 14/2013, de 27 de septiembre, de Apoyo a los Emprendedores y su Internacionalización [Ley 14/2013, de 27 de septiembre, de apoyo a los emprendedores y su internacionalización (BOE núm. 233, de 28 de septiembre de 2013)].
REFLEXIONES SOBRE LA CONTESTABILIDAD DE LOS MERCADOS EN EL DERECHO DE LA COMPETENCIA
Authors:   Universidad de Murcia, Soria Bastida Juan Pablo
Published: November 2023

En este artículo se presenta una aproximación a los elementos esenciales que conforman la teoría de los mercados contestables o disputables desarrollada por los economistas Baumol, Panzar y Willig en su conocida obra Contestable Markets and the Theory of Industry Structure, su vigencia en la aplicación del Derecho de la Competencia, y su función como criterio orientador para la política de competencia.
On the three-valued expansions of Kleene's logic
Authors:   Institute of Philosophy, Russian Academy of Sciences, Devyatkin Leonid Yu.
Published: November 2023

The paper is devoted to one of the most famous three-valued systems – Kleene's logic. The expressive capabilities of Kleene's logic and its three-valued expansions are described. We present two results. First, all possible three-valued expansions of Kleene's logic are found up to equivalence with respect to the mutual definability of connectives. It is shown that there are only twelve such expansions. This list includes both logics already known in the literature and completely new ones. For the found expansions, we describe the structure of the lattice ordered relative to the expressive power of its elements. Secondly, for Kleene's logic and its three-valued expansions we find how many extensions each of these logics has in the same language. Kleene's logic has only two proper extensions: the classical and the trivial ones. Generally, a three-valued logic in which Kleene's matrix is definable contains no more than three proper extensions: the classical one, the trivial one, and an intermediate logic, determined by the product of the the original logic's matrix and the matrix of classical logic in the same signature. Intermediate logics exist only for two types of three-valued expansions of Kleene's logic: in expansions equivalent to Łukasiewicz's logic, and in logics whose matrices contain both a bivalent submatrix, the universe of which consists of the classical truth values, and a submatrix, the universe of which consists the intermediate value alone. All three-valued expansions of Kleene's logic that do not preserve the classical values have only one extension of their own – the trivial one.
Bile acids enrichment supports tumor aerobic glycolysis and
establishes immunosuppressive microenvironment
Authors: Zhang Zongde , Jiang Hongyu , Li Xingjie , Tan Jinzhuo , Wu Renlan
Published: November 2023

Fast-growing solid tumors employ aerobic glycolysis to meet the demand balance of energy and anabolic growth and promote tumor immune evasion. The tumor microenvironment (TME) factors that support aerobic glycolysis have not been determined. Here, we show that microbiota-metabolized bile acids (BA) were highly enriched in melanoma and breast cancer. Depletion of bile acids suppresses tumor progression, increases T cell infiltration, and alleviates T cell exhaustion. Transcriptome analysis reveals that a lack of bile acid improves the expression of oxidative phosphorylation genes in vivo. Bile acids enrichment supports aerobic glycolysis via FXR-RARα interaction. Depletion of BA impairs the tumor's immune suppressive barrier and reduces the protein levels of FXR and RARα. Our study unveils that a
mechanism of tumor progression modulated BA-RA signaling by
FXR-RARα interaction and bile acid as a latent target, which suggests a possible way for tumor diagnosis and treatments.
Physical and Chemical Properties of New Carambola Variety Bintang Mas at Three Different Maturity Stages
Authors: Shapawi Zahrah-Izati Azhar , Ariffin Siti Hajar , Shamsudin Rosnah , How Syahmeer , Baharom Ahmad Hafiz
Published: November 2023

The authors have requested that this preprint be removed from Research Square.