bluuebunny/crossref_metadata_2025 huggingface dataset:
Ablación química de la vesícula biliar con hipoclorito de sodio en un modelo animal
Authors: Jover Clos Rafael J. , Álamo Juan P. , Matsuzaki Mónica , Dionisio de Cabalier María Elisa , Bustos Héctor F. , Gramatica Luis
Published: September 2024

Introduction: The cholecystectomy is the current treatment of the biliary lithiasis. Nevertheless there have been attempts in order to eliminate the gallbladder epithelium and to generate the sclerosis of the organ using chemical substances, heat and laser.Objetive: Sodium hypochlorite and fibrin glue is proposed to achieve the ablation of the gallbladder mucosa and sclerosis.Materials and methods: Thirty rabbits were divided into three groups of 10. Accessing surgically to the gallbladder, sodium hypochlorite was injected, afterward the same was done with fibrin glue to occlude the cystic duct and collapse the organ lumen, avoiding the bile reflux. In the control groups ethanol plus fibrin adhesive and physiological solution was used. In day 65 the animals were sacrificed and the result of the procedure was observed macroscopic and histologically.Results: Eight of the gallbladders treated with sodium hypochlorite disappeared leaving a small subhepatic scar. There were no intra nor postoperative complications. In the group of the ethanol the result was successful only in one case, and with saline solution there was no ablation. A significant difference exists for the group treated with sodium hypochlorite plus fibrin glue compared to the ethanol plus fibrin adhesive group (p <0,0055) and the saline solution group (p <0,0007).Conclusion: In this experimental model there was possible the ablation of the gallbladder using sodium hypochlorite as sclerosing agent and fibrin glue to collapse the lumen and to occlude the cystic duct.
Alcoholismo: aportes prácticos para su abordaje
Authors: Zárate Fabián E. , Cortés Linda P. , Passero Alfredo C. , Butti Abel Luis Lázaro
Published: September 2024

Mass consumption of alcohol as a phenomenon social development, both in societiesindustrialized as in the zones a call for attention to the needs of the population.Health Teams to find strategies that lead to some solution to this problem.
Hematoma hepático en el síndrome HELLP
Authors: Alassia Maida , Buteler María Marta , Caffaratti Cecilia , Bollatti Hector , Caratti Maria Marta
Published: September 2024

Objective: The purpose of this study was to review our experience with patients having hepatic rupture or hematoma caused by HELLP syndrome.Materials and Methods: Descriptive simple cross sectional retrospective study. A review was performed of medical records of all patients admitted at our Hospital´s intensive care unit having HELLP syndrome during pregnancy or puerperium between February 1999 and February 2010. Patients complicated with hematoma or hepatic rupture were included. Results: Three cases were identified. The average maternal age was 35 years old and the average gestational age at delivery was 33 weeks. The most frequent signs and symptoms were sudden onset of abdominal pain and shock. A distinctive laboratory finding was anemia. Surgical treatment was omental patching in one of the patients and it was conservative with drainages in the other two cases. Maternal and perinatal mortality were 33 %.Conclusion: Based on our experience and the literature review, we can conclude that hepatic hematoma and rupture associated with HELLP syndrome represent a life-threatening complication in which early detection is very important to achieve a proper diagnosis and treatment. Patients should be treated by a multidisciplinary team in reference centers being carefully followed with adequate hemodynamic support and regular images to improve the survival maternal rate.
Divertículo uretral complicado
Authors: Pereyra Zenklusen Alvaro , Muiño G.
Published: September 2024

19-year-old female patient, previously healthy, presenting with acute urine retention, requiring intermittent bladder sounding.
Mal de Chagas-Mazza: Fisiopatogenia y nuevas propuestas de tratamientos
Authors: Rivarola Hector Walter , Paglini de Oliva Patricia Adriana
Published: September 2024

Chagas disease, discovered 103 years ago, is still one of the main endemics affecting the American continent. Between 15 and 16 million people are infected with Trypanosoma cruzi and more than 25 million people are at risk of contracting the disease. In 2008, Chagas disease killed an estimated 10,000 people. It is considered to be the parasitic disease with the highest economic burden in Latin America due to its prolonged chronicity; in addition, it has begun to be a challenge for doctors in the United States and European countries due to the immigration of people coming from countries in the endemic zone.
Hematoma subseroso del colon
Authors: Maldonado Pablo Sergio , Pereyra Zenklusen Alvaro , Muiño G.
Published: September 2024

A 21-year-old male patient reports having suffered a blow while participating in a rugby match.
Mycobacterium fortuitum: Dos pacientes y un mismo cirujano
Authors: Bermejo Joaquín , Pascale María Laura , Borda Noemi , Notario Rudolfo
Published: September 2024

We describe two cases of surgical site infections due to Mycobacterium fortuitum after plastic surgery. Both patients were assisted by the same surgeon on differents hospitals. Both patients recieved combined antibiotic treatment and surgical debridement or multiple aspirative puntures. The final evolutions were satisfactory.
Insomnio: Prevalencia en un Hospital de la Ciudad de Córdoba
Authors: Fernandez M.E. , Lopez S.M. , Cazaux A. , Cambursano V.H. , Cortes J.R.
Published: September 2024

Introduction: Insomnia is a sleep disorder characterized by a deficient or poor quality sleep, with adverse daytime consequences. Prevalence is 30-50% in adults and can be associated with depression or lead to the development of this condition. Despite the high prevalence rates, is a unrecognized, misdiagnosis and undertreated. There is not much publications about its prevalence in patients with chronic diseases.
 Objectives: to determine prevalence and clinical characteristics of insomnia in outpatients with chronic diseases.
Materials and methods: Prospective observational cross-sectional descriptive study. Insomnia was defined based on ICSD-2criteria. The data collection was performed by a questionnaire.
Results: We surveyed 100 patients who attended the consultation of various clinical specialties, mean age 50 years old, 57% were women. Sixty nine per cent of them met criteria for insomnia. The most prevalent diseases were hypertension: 57%, asthma 20%, diabetes: 18% and hypothyroidism: 17%. Among patients with insomnia, 62% were women, 35% had insomnia without another illness, and the remaining 65% had secondary conditions associated with insomnia (60% depression). 25% of patients consulting for insomnia ever. The prevalence of criteria for depression in outpatients with chronic diseases was 52%, amounting to 63% in patients suffering from insomnia.
Discussion: The prevalence of insomnia in patients with chronic diseases is high (in outpatients with chronic disease: 69%), higher than the average rate described in the general population. It is an undertreated condition.Conclusions: The prevalence of insomnia in patients with chronic diseases is high, it is underdiagnosed and undertreated. It is associated with depression in high rate.
Paradigma actual de la artritis reumatoidea
Authors: Alba Paula B. , Exeni Ida Elena
Published: September 2024

La Artritis Reumatoidea (AR) es la artropatía inflamatoria más frecuente a nivel mundial con una prevalencia estimada del 0,5 al 1% en los países desarrollados. Todos los aspectos del manejo médico de la AR han sufrido cambios sustanciales en los últimos 20 años. A mediados de los años 90 numerosos artículos reportaban la instalación de daño estructural precoz en pacientes con AR aún asintomática que si no era diagnosticada y tratada, llevaba a que un número superior a 50% de los pacientes llegaran a discapacidad funcional con el transcurrir del tiempo. Además empezó a considerarse enfermedad sistémica, con fuertes implicancias en la calidad de vida, y también empezaron a cuantificarse sus consecuencias sociales: aumento de costos directos e indirectos, bajas tasas de productividad, mortalidad prematura y jubilación temprana.
Incidencia y factores de riesgo de endofugas en el tratamiento endovascular de los aneurismas aorticos
Authors: Baez Julio , Cura Angela Bettiana , Figueroa Adolfo , Paulazo Carolina , Castro Pizarro Rodolfo , Garcia Brasca Daniela , Castrillon Maria Elena , Pieroni Mario
Published: September 2024

Background: endovascular aneurysm repair (EVAR) reduces morbidity and hospital stay compaired with open surgical repair. Endoleak is a common complication of the procedure. The resulting increase of pressure within the sac may expand the aneurysm with the following risk of rupture. The aim of this study was to recognize the incidence of endoleak in tomographic controls of the patients who underwent endovascular repair at our hospital as well as identify the risk factors associated with this complication. Methods: all consecutive patients who underwent endovascular aneurysm repair at our hospital between 2008, February until 2012, February were restrospectively enrolled in the study, excluding those who were lost at follow-up. 43 patients were included, aged 70,5 ± 6 (men: 88%). The endpoint was endoleak incidence at 1, 6, 12th months after the intervention in the control tomography, and its association with underlying risk factors: hypertension, Smoking, chronic obstructive pulmonary desease and the diameter of the aneurysm.Results: eleven (11%) patients developed endoleak (type I 9%, type III 2%). All were infrarrenal aortic aneurysms. The anteroposterior diameter of the aneurysm (more than 60mm) showed a trend toward statistical significance as a risk factor (30% vs. 6%; p:0,073). No relationship was found with gender, age, COPD, smoking or hypertension. Conclusion: endoleak after endovascular aneurysm repair is a common complication. The size of the aneurysm might be a risk factor of the event.
Sindrome de Ovario Poliquístico
Authors: Fux Otta Carolina , Fiol de Cuneo Marta , Szafryk de Mereshian Paula
Published: September 2024

Polycystic ovary syndrome (PCOS), the most common gynecological endocrinopathy in women of reproductive age, is characterized by hyperandrogenism, chronic anovulation and /or polycystic ovaries. Although the cause of PCOS is still unknown, there are several hypotheses attempting to explain the primary defect; the most commonly accepted is insulin resistance. Due to its high prevalence, the patients have increased risk of developing metabolic and cardiovascular alterations. The compensatory hyperinsulinemia contributes to hyperandrogenism in different ways: by stimulating ovarian androgen synthesis and inhibiting hepaticproduction of sex hormone binding globulin. From the study of the intrauterine environment in recent years it has been suggested that PCOS may have an origin in utero associated with prenatal exposure to androgens.The aim of this paper is to review the main mechanisms proposed to cause the syndrome
Reporte de eventos adversos en una unidad de cuidados intensivos de Tunja, Colombia
Authors: Riveros Efraín , Amado Paula , Zambrano Paula
Published: September 2024

Introduction: Patient safety in critical areas has been subject of several studies. In Colombia, there is a growing conscience about adverse events management. This study explores the first phase of this management: report in a typical private intensive care unit.Objective: To assess adverse event report at a Colombian tertiary level institution, through frequency and report category assessment.Methods: A descriptive study regarding adverse event report rates during 2011 period in Clinica de los Andes de Tunja, was carried out, through frequency and report category assessment. Adverse event report rate was defined as the number of reports per 1000 patient bed. We reported major and minor categories of events.Results: A total of 383 admissions (2374 patient days) were recorded. 54 adverse events were reported (rate of 22,74 per 1000 patient days). The most frequent events were related to intravenous route (55%) (CI 95% 50,1-58,3) followed by process deviation (22%)(CI 95% 18,2-26,1).Conclusions: An adverse event report rate closeto the upper limit of literature reports numbers was found. Probably, there is still non quantified under-report of adverse events, likely due to cultural factors.
Malformación pulmonar, secuestro pulmonar intralobar
Authors: Debernardi Diego M. , Bustos Mario E.F. , Padilla Alvarez F. , Avalos Sebastián
Published: September 2024

Pulmonary sequestration is a congenital, bronchial and arterial congenital malformation in which a part of the lung parenchyma has no communication with the tracheobronchial tree and receives its blood supply from a systemic artery.
Disease Mongering in Neurological Disorders
Authors: Kochen Silvia , Cordoba Marta
Published: September 2024

If out of curiosity, the readers take a few seconds to search on the Internet the expression “diseases mongering”, they will see that "to promote or sell disease" is an enforced definition. They will also find out that the term competes in popularity with many frequently used words, even with popular actors or sportsmen. Besides it will appear a number of “new diseases" or novel groupings or categories of “old diseases”. The main and common characteristic of all these "diseases" is that they are amenable to be treated with drugs. The first reason seems to be the advances in scientific knowledge. However, we should incorporate other considerations such as the interest of the pharmaceutical industry in selling their products...
Validity and reproducibility of a food frequency questionnaire to assess lipid and phytochemical intake
Authors: Perovic Nilda Raquel , Defagó Maria Daniela , Aguinaldo Anabel , Joekes Silvia , Actis Adriana Beatriz
Published: September 2024

Background: epidemiological studies have been related food intake with the incidence of non-transmissible chronic diseases.
Objective: the purpose of the present study was to analyze the validity and reproducibility of a food frequency questionnaire (FFQ) aimed at assessing lipid and phytochemical intake.
Material and Methods: FFQ was administered to 45 people of both sexes, aged between 20 and 72 years old and resident in Cordoba, Argentina. The FFQ included 257 questions referring to foods, their consumption frequency and portion size. Regarding consumption of fruit and vegetables, the season was also taken into account. The questionnaire was applied at two different periods (FFQ1 and FFQ2) with a break of six months in between. As a reference, the 24-hour dietary recall was used (24HDR) three times. The mid intake of FFQ1-FFQ2, the 24HDR-FFQ2 median intake, median difference, Mean Absolute Deviation from the median differences (MAD), Wilcoxon signed rank sum test and Spearman rank order correlation coefficients were calculated to analyze the accuracy of the FFQ data.
Results: the correlation coefficients for FFQ1-FFQ2 varied from 0.52 for 20:5 n3 eicosapentanoic (EPA) fatty acid to 0.89 for 4:0 butyric fatty acid (p<0.05). For 24HDR-FFQ2, the values ranged from 0.19 for lycopene to 0.93 for EPA fatty acid (p<0.05).
Conclusion: the analysis carried out showed an acceptable validity and reproducibility of the FFQ, thus enabling it to be used in research relating the intake of lipids and phytochemicals and the risk of non-transmissible diseases.
Avanzando la investigación en salud pública en latinoamerica
Authors: Susser Ezra
Published: September 2024

Este número especial dedicado a la Salud Mentalde la Revista de la Facultad de Ciencias Médicas,representa una contribución importante al avancede las investigaciones y el entrenamiento en saludmental en el ámbito público en América Latina. Loseditores (así como los autores) merecen un especialreconocimiento por haber concebido e implementadola presente publicación conjunta. En estabreve introducción, destaco cuatro formas en lasque sus esfuerzos probablemente aceleren el progresoen este campo.
Advancing public mental health research in Latin America
Authors: Susser Ezra
Published: September 2024

This special issue on Mental Health of the Journal of the School of Medicine, represents a significant contribution to the advance of public mental health research and training in Latin America. The editors (as well as the authors) deserve much credit for having conceived and implemented the joint publication of these papers. In this brief introduction, I draw attention to four ways in which their effort is likely to accelerate progress in this field...
Factores asociados a presencia de células neoplásicas secundarias en líquido cefalorraquídeo de pacientes con sospecha de Meningitis Carcinomatosa
Authors: Warley Fernando , Bonella María Belén , Giunta Diego Hernan , Elizondo Cristina M , Ferreyro Bruno Leonel
Published: September 2024

Antecedentes: El aumento de la sobrevida en pacientes oncológicos incrementó la incidencia de meningitis carcinomatosa (MC). El diagnóstico precoz es mandatorio.Objetivo: Identificar factores asociados a presencia de células neoplásicas en líquido cefalorraquídeo de pacientes con sospecha de MC.Materiales y Métodos: Estudio de corte transversal en pacientes adultos con tumores sólidos y sospecha de MC entre 2004 y 2014 que realizaron al menos una punción lumbar en el Hospital Italiano de Buenos Aires. Se clasificaron como positivos los pacientes con detección de células neoplásicas por anatomía patológica en líquido cefalorraquídeo. Se evaluó la asociación de cada factor (características del cáncer, clínica de compromiso de sistema nervioso central, laboratorio) con la presencia de meningitis carcinomatosa utilizando un modelo de regresión logística.Resultados: Se incluyeron 77 pacientes con sospecha de MC: la edad media fue de 62 años (DS 13.1) y 58.4% fueron mujeres (45). La patología de base más frecuente fue el cáncer de pulmón 29.9% (23), seguido del de mama 23.4% (18). Se detectó MC en 23.4% (18) pacientes. En el análisis univariado, la glucorraquia, el recuento de leucocitos en LCR, el compromiso meníngeo por resonancia magnética, la cefalea y el síndrome confusional se asociaron significativamente con MC. En el análisis multivariado la única variable que conservó su asociación con el evento fue la glucorraquia (OR 0.93 IC95% 0.9 - 0.97, p<0.001).Discusión: A medida que se incrementa la glucorraquia, la probabilidad de tener MC disminuye. Estos hallazgos son compatibles con otros estudios previos.
The Safety and Efficacy of Left Atrial BOX Ablation in Persistent Atrial Fibrillation: A Meta-Analysis
Authors: Li Yang , Xi Yin , Zhang Wenyu , Hao Jie
Published: September 2024

Background: Circumferential pulmonary vein isolation (CPVI) has a high recurrence rate in managing persistent atrial fibrillation (AF). While some studies suggest that augmenting CPVI with additional left atrial BOX ablation can diminish this recurrence rate among patients with persistent AF, this approach remains controversial. This meta-analysis assesses the safety and efficacy of adjunctive left atrial BOX ablation in treating persistent atrial fibrillation. Methods: We conducted a comprehensive literature search across China National Knowledge Infrastructure (CNKI), PubMed, Web of Science, and Cochrane Library, focusing on randomized controlled trials. The primary outcome was the recurrence rate of any atrial arrhythmias (AAs) within one-year post-treatment, with the secondary outcome being the frequency of adverse events related to the surgery. Results: The combination of CPVI and left atrial BOX ablation did not lead to a significant reduction in the overall recurrence rate of atrial arrhythmias (risk ratios (RR) = 0.86, 95% confidence interval (CI) = 0.73–1.02, I2 = 35%). However, subgroup analyses revealed that this therapeutic approach significantly decreased the recurrence rates of all atrial arrhythmias (RR = 0.67, 95% CI = 0.49–0.92, I2 = 15%) and specifically atrial fibrillation (RR = 0.53, 95% CI = 0.37–0.77, I2 = 0%) in patients with a left atrial diameter ≤44 mm. Notably, there was no significant increase in the incidence of procedure-related adverse events (RR = 1.04, 95% CI = 0.56–1.94, I2 = 0%). However, the durations of both the ablation (mean difference (MD) = 19.77, 95% CI = 15.84–23.70, I2 = 0%) and the overall procedure (MD = 15.64, 95% CI = 6.99–24.29, I2 = 0%) were longer due to the additional ablation steps. Conclusions: In patients with smaller left atrial diameters, augmenting CPVI with left atrial BOX ablation significantly lowers the recurrence rates of atrial arrhythmias and atrial fibrillation without elevating surgical risk levels.
Wearable Devices Based on Bioimpedance Test in Heart-Failure: Design Issues
Authors: Scagliusi Santiago F. , Giménez-Miranda Luis , Pérez-García Pablo , Olmo-Fernández Alberto , Huertas-Sánchez Gloria , Medrano-Ortega Francisco J. , Yúfera-García Alberto
Published: September 2024

Heart-failure (HF) is a severe medical condition. Physicians need new tools to monitor the health status of their HF patients outside the hospital or medical supervision areas, to better know the evolution of their patients’ main biomarker values, necessary to evaluate their health status. Bioimpedance (BI) represents a good technology for sensing physiological variables and processes on the human body. BI is a non-expensive and non-invasive technique for sensing a wide variety of physiological parameters, easy to be implemented on biomedical portable systems, also called “wearable devices”. In this systematic review, we address the most important specifications of wearable devices based on BI used in HF real-time monitoring and how they must be designed and implemented from a practical and medical point of view. The following areas will be analyzed: the main applications of BI in heart failure, the sensing technique and impedance specifications to be met, the electrode selection, portability of wearable devices: size and weight (and comfort), the communication requests and the power consumption (autonomy). The different approaches followed by biomedical engineering and clinical teams at bibliography will be described and summarized in the paper, together with results derived from the projects and the main challenges found today.
Association of Adding Salt to Foods and Potassium Intake with Incident Atrial Fibrillation in the UK Biobank Study
Authors: Park Yoon Jung , Yang Pil-Sung , Park Bo Eun , Park Jong Sung , Jang Eunsun , Kim Daehoon , Kim Hong Nyun , Kim Namkyun , Lee Jang Hoon , Cho Yongkeun , Sung Jung-Hoon , Joung Boyoung
Published: September 2024

Background: High sodium and low potassium consumption are related to hypertension and cardiovascular disease. We aimed to determine the relationship between the frequency of salt addition and potassium consumption with the risk of new-onset atrial fibrillation (AF). Methods: Our study used the UK Biobank cohort, which included over 500,000 individuals enrolled from the United Kingdom between 2006 and 2010. This study involved 416,868 participants who filled out the dietary recall regarding the frequency of salt addition. Results: During follow-up, 19,164 (4.6%) developed AF. The incidence of new-onset AF was increased based on the frequency of salt addition (never/rarely 3.83; always 4.72 per 1000 person-years). Compared with the group that never/rarely added salt, those adding salt always were at significantly higher risk of incident AF after adjusting for multiple variables (hazard ratio (HR) 1.15; 95% confidence interval (CI) 1.06–1.24), and additional adjustment of dietary and total energy consumption (HR 1.37; 95% CI 1.08–1.73). In the subgroup analysis, the risk of AF incident according to the frequency of salt addition significantly increased in low urine potassium levels compared to high (p for interaction = 0.046). In the subgroup analysis for AF patients, higher salt addition frequency was related to increased all-cause mortality. Conclusions: Our study demonstrated that adding salt to foods more frequently increases the risk of incident AF, even after adjusting for dietary and total energy consumption. In the high urine potassium group, the impact of high sodium consumption on incident AF was attenuated.
The Effect of Tolvaptan on Metabolism and Electrolyte Homeostasis in Patients with Heart Failure: A Systematic Review and Meta-Analysis
Authors: Xiao Yao , Chen Yue , Zuo Xianghao , Mutalifu Kadireya , Chen Xiaoping , Liu Kai
Published: September 2024

Background: This study aimed to investigate the effect of tolvaptan on metabolism and electrolyte homeostasis in patients with heart failure (HF). Methods: Literature databases, such as PubMed, EMBASE, the Cochrane Library, China National Knowledge Infrastructure, VIP, and WanFang Data, were systematically searched for relevant trials from inception to November 4, 2023. We used the fixed effect model to combine the effect sizes and used I2 to test heterogeneity. Funnel plots were plotted to assess publication bias. Results: 16 studies were eligible for further analysis. No significant differences were identified in the incidence of hyperuricemia between the tolvaptan group and the placebo group (odds ratio (OR) = 1.23, 95% confidence interval (CI) = 0.97 to 1.55, p = 0.09). Tolvaptan decreased the levels of blood uric acid compared to traditional diuretics (mean difference (MD) = –82.8, 95% CI = –96.48 to –69.13, p < 0.00001). There was no significant difference in hypernatremia (OR = 1.62, 95% CI = 0.66 to 3.96, p = 0.29) and hyperkalemia (OR = 1.17, 95% CI = 0.93 to 1.48, p = 0.18) between the tolvaptan and control groups. Conclusions: Tolvaptan reduced the level of blood uric acid compared to conventional diuretics, and could be used as a substitute for traditional diuretics for HF patients with a high risk of gout.
Effectiveness of the 5As Model-Based Transitional Care Program among Chinese Patients with Type B Aortic Dissection Post-TEVAR: A Randomized Controlled Trial
Authors: Tu Jianxin , Zhou Jing , Li Xiumao , Zhang Qin , Luo Mingxian , Zhou Jiamei
Published: September 2024

Background: Thoracic aortic endovascular repair (TEVAR) is the primary treatment for Stanford type B aortic dissection (type B AD). However, patients often encounter significant difficulties post-TEVAR that endanger their safety when transitioning from hospital- to home-based care. Moreover, information on the ideal transitional care for patients with type B AD post-TEVAR is scarce in China. This single-masked randomized clinical trial aimed to assess the effectiveness of the Assess, Advise, Agree, Assist, and Arrange (5As) model-based transitional care in improving discharge preparation level and transitional care quality post-TEVAR among patients with type B AD in China. Methods: This study was conducted at a hospital in China between January 2021 and October 2021. Patients with type B AD were randomly divided into intervention and control groups. Participants in the intervention group received the 5As model-based transitional nursing care. The 5As model is an evidence-based intervention strategy comprising: (1) Assess: assessing the preoperative cardiovascular risk behavior of patients with AD. (2) Advise: making suggestions according to the risk behaviors of the patients. (3) Agree: reaching a consensus on goals and action plans by making decisions with the patients and their families. (4) Assist: assisting patients in solving obstacles to implementing health plans. (5) Arrange: arranging follow-up visits according to the actual situation of the patients and guiding them in adhering to a schedule. The control group received the usual nursing care for the same duration and number of follow-up visits. A trained research nurse collected all the baseline data of the patients on admission, assessed discharge readiness level (using the Readiness for Hospital Discharge Scale) on the day of discharge, and collected transitional quality of care (by the Care Transition Measure-15) data on day 30 after discharge. Results: Overall, 72 patients with type B AD were recruited. Discharge readiness level and transitional care quality in the intervention group were significantly superior to those in the control group. Conclusions: This study showed that the 5As model-based transitional care program can effectively promote discharge readiness and transitional care quality of patients with type B AD post-TEVAR. Clinical Trial Registration: The Chinese Clinical Trial Registry Center: ChiCTR2200060797 (https://www.chictr.org.cn/showproj.html?proj=167403).
Endoscopic typing of adenomas of the large papilla of the duodenum
Authors: Starkov Yu. G. , Vagapov A. I. , Zamolodchikov R. D. , Dzhantukhanova S. V.
Published: September 2024

Adenomas of the major duodenal papilla are benign neoplasms, but due to their high tendency to malignancy, they must be removed. Currently, in the treatment of patients with adenomas of the major duodenal papilla, both surgical and various intraluminal endoscopic interventions are used. To select the optimal method of treatment, it is necessary to type adenomas of the major duodenal papilla, which provides for an accurate topical description of the tumor, taking into account the size, growth and spread to the walls of the duodenum, the terminal sections of the common bile duct and the main pancreatic duct. The endoscopic typing developed by us for adenomas of the major duodenal papilla (endoscopic classification) allows us to determine the most effective and safe method of surgical intervention for each type of neoplasm.
Endoscopic diagnosis and evaluation of the effectiveness of treatment of small cell lung cancer
Authors: Vakurova E. S. , Setdikova G. R. , Shikina V. E.
Published: September 2024

This publication examines the possibilities of bronchoscopy in the diagnosis of primary small cell lung cancer and the assessment of the effectiveness of treatment. Endoscopic semiotics of small cell lung cancer is considered. A clinical observation of a patient with widespread small cell lung cancer is presented: primary diagnosis and assessment of the effectiveness of the course of chemotherapy.
Assessment of the diagnostic significance of endoscopic ultrasonography in the differential diagnosis of formations of the hepatopancreatoduodenal zone
Authors: Abilbekova B. A. , Khamitova I. M. , Laryushina E. M.
Published: September 2024

Purpose of the work. To study the structure of the hepatopancreaticoduodenal zone (HPD) masses according to the endosonographic picture and to estimate the diagnostic informativeness of endoscopic ultrasonography (EUS) in diagnostics of these masses in comparison with ultrasound examination of HPD (ultrasound of HPD) and computer tomography of abdominal cavity organs (CT of OBP) with contrasting. Materials and Methods. A retrospective analysis of medical records of 71 patients with GDZ masses who underwent inpatient treatment in the department of abdominal surgery and applied for diagnostic purposes to the endoscopic centre of Karaganda Multidisciplinary Hospital No.3 for EUS for the period from January 2021 to December 2022 was carried out. Results and discussion. Sensitivity of EUS in differential diagnostics of PG tumours, hepaticocholedochal dilatation, vascular invasion and metastasis to regional lymph nodes was 85%, 94,12%, 64,71% and 100% respectively, specificity - 95,93%, 100%, 80% and 92% respectively. Conclusion. Correct assessment of all manifestations of a tumour influences the choice of treatment tactics and consequently its immediate and long-term results. EUS is an effective method of differential diagnostics of pseudocysts and cystic tumours of PG, tumours of large duodenal papilla (LDP), as well as biliary tract neoplasms.
Have you ever wondered how important it is for us to transition from manual processing of endoscopes to automated!?
Authors: Avdyugina A. L.
Published: September 2024

Goal: work, reduce the risk of developing infections associated with the provision of medical care and draw the attention of managers to the volume of work performed by a nurse and reduce the burden on staff through the purchase of high-quality equipment. Materials and methods. In connection with our goals, it is important for us to understand what we had and what we came to. Try to make the nurse’s work easier and maintain ergonomic movement.
Rethinking Vividness: Semantic moreso than perceptual features drive the recall vividness of complex pictures
Authors: Morales-Torres Ricardo , Davis Simon , Cabeza Roberto
Published: September 2024

While some memories are vivid and detailed, others are vague and indistinct. Although this is a ubiquitous experience, the cognitive mechanisms underlying these differences are not well understood. To investigate this issue, in Experiment 1 (N=122), we examined how the subjective feeling of memory vividness relates to the perceptual (i.e., color and brightness) and semantic (i.e., the category of a stimulus) properties of naturalistic images. Surprisingly, our findings showed that while perceptual properties moderately contribute to the vividness of visual memories, the primary driver is semantic properties. Moreover, in Experiment 2 (N=132), by employing different Deep Neural Networks (DNNs) to select stimuli based on their semantic features, we could reliably identify stimuli that generate vivid memories. Our results demonstrate, at multiple levels of inference, that although vivid memories are often compared to perception, this subjective quality of memory is strongly influenced by our knowledge of the world.
Advancing Parkinson’s Disease Research in Africa: A Strategic Training Framework of the Global Parkinson’s Genetics Program (GP2)
Authors: Step Kathryn , Eltaraifee Esraa , Elsayed Inas , Rasaholiarison Nomena , Okubadejo Njideka Ulunma , Walker Richard , MOHAMED Wael , Rizig Mie , Bandres-Ciga Sara , Noyce1 Alastair J. , Dey Sumit , Program Global Parkinson’s Genetics , Bardien Soraya , Perinan Maria Teresa
Published: September 2024

Not applicable
VolFe: an open-source tool for calculating melt-vapor equilibria including silicate melt, carbon, hydrogen, sulfur, and noble gases
Authors: Hughes Ery , Liggins Philippa , Wieser Penny , Stolper Edward
Published: September 2024

VolFe is an open-source flexible and adaptable thermodynamic framework in Python for calculating the equilibrium composition of melt and vapor. VolFe considers basaltic through rhyolitic melts including the volatiles carbon, hydrogen, sulfur, and noble gases. VolFe models both reduced and oxidised systems due to the range of melt and vapor species included. Hence, VolFe is applicable to terrestrial (e.g., mid-ocean ridges to arcs) and extra-terrestrial (e.g., the Moon and Mars) systems. New parameterisations of “model-dependent variables” (e.g., volatile solubility functions, sulfide-saturation conditions, fugacity coefficients, etc.) can be added as new experimental studies come out, enhancing VolFe’s future applicability. The main calculations currently included in VolFe are the pressure of vapor-saturation based on the dissolved volatile content of melts; open- and closed-system degassing and regassing; and an oxybarometer based on the melt sulfur content. As an example, we apply VolFe to melt inclusion and matrix glass data from the Marianas arc.
Awareness of both global uncertainty and feedback in human time estimation
Authors: Bader Farah Nikhath , Desai Chetan Kaushik Kaushik , Wiener Martin
Published: September 2024

Recent behavioral studies have shown that humans possess self-awareness of their individual timing ability in that they can discern the direction of their timing error. However, in these studies which included a single repeat (re-do) trial for each duration, it remains unclear whether the reduction in errors in the Re-do trials was due to self-awareness of individual timing ability or because the participants used the feedback from the initial trials to improve on the re-do ones. To investigate this further, we conducted a behavioral study in which subjects were divided into two groups: one in which the “Re-do” phase occurred frequently, but not always (80% of trials; called the “high double” group), and one in which Re-do trials were rare (20% of trials; called the “low double” group). This was done to test the possibility of subjects relying on the Re-do trials as a method of improvement. Subjects significantly improved in their performance on Re-do trials regardless of whether re-dos were rare or frequent. Further, an unexpected finding was observed, where subjects in the low double group also overall performed better than those in the high double group. This finding suggests that subjects, knowing that re-do opportunities were rare, engaged better timing at the outset; yet, these subjects still improved on Re-do trials, suggesting humans are able to incorporate both global uncertainty and feedback.
Improving Vaccine Attitudes and Misinformation Resistance through Gamification: A Pilot Study in Kenya and Uganda
Authors: Cook John , Njomo Doris , Aura Caroline , Wamalwa Benson Munyali , Abeyesekera Surangani , Ssanyu Jacquellyn Nambi , Kabwijamu Lydia , Ofire Michael , Lepage Chelsey , Thomson Angus , Waiswa Peter , Cook Wendy , Knobler Stacey L. , Hopkins Kathryn L.
Published: September 2024

Misinformation about vaccines poses a significant challenge to vaccination efforts, including in low- and middle-income countries. Pre-emptive strategies to neutralize the influence of misinformation have gained attention, with psychological inoculation theory found to be an effective framework. Digital games have emerged as engaging, cost-efficient, and scalable tools to implement inoculation interventions and promote health-related behaviors. The Cranky Uncle Vaccine game, co-designed in Uganda, Kenya, and Rwanda, and piloted in Kenya and Uganda, aimed to establish the effectiveness of Cranky Uncle Vaccine in increasing vaccine acceptance, intent to get vaccinated, and discernment between vaccine facts and fallacies, as presented in this paper. Pre- and post-game surveys identified significant improvement in vaccine attitudes, with participants showing a more positive stance toward vaccination after playing the game. Among participants who expressed vaccine hesitancy before the game, 58% switched to being somewhat or very likely to get vaccinations after playing the game. Perceived reliability of vaccine facts increased while perceived reliability of fallacies decreased, indicating improved ability to distinguish true from false statements. Demographic factors such as education and age moderated the effectiveness of the game, with greater effects seen in lower-educated and older participants. The game's emphasis on the importance of vaccination, explanation of misleading techniques, and interactive learning contributed to positive outcomes, improving vaccine attitudes and reducing the influence of vaccine misinformation. Our findings highlight the relevance of game-based interventions in addressing misinformation and promoting vaccine acceptance.
Evaluating youth mathematical ability online and on-site with the Stanford Mental Arithmetic Response Time Evaluation (SMARTE)
Authors: Guillaume Mathieu , Roy Ethan , Van Rinsveld Amandine , Sawi Oliver , Zhao Priscilla , McCandliss Bruce
Published: September 2024

Mathematical knowledge is essential to function properly in our modern society. It is therefore crucial for teachers and clinicians to be able to assess learners’ mathematical abilities with validity, reliability, and speed. Here we describe a new tablet-based assessment app designed to measure math fluency, the Stanford Mental Arithmetic Response Time Evaluation (SMARTE) tool. SMARTE consists of three 2-minutes tasks (non-symbolic dot enumeration, math fluency, and math recall). We analyzed data from 6,855 participants (3,262 female, mean age: 12.97 years) who completed SMARTE in year 3 of the Adolescent Brain Cognitive DevelopmentSM study. Because of the COVID-19 crisis, 2,682 participants were tested online while 1,159 participants were tested in person as the original protocol called for. Our analyses revealed that the SMARTE score and sub-scores highly correlated with each other. Overall fluency metrics revealed more problems per unit time were completed in the laboratory setting, yet a host of experimental contrasts that manipulated the cognitive demands across problem types produced equivalent effects across both settings, suggesting these effects are quite robust across variations in study setting.
A Primer on Open Science for Cognitive Psychologists
Authors: Pennington Charlotte Rebecca
Published: September 2024

Psychological science is said to be facing a ‘replication crisis’ with widespread concerns regarding the replicability, reproducibility, and transparency of its findings. This crisis has led to the fast-paced advancement of open science, with a series of new practices proposed to mitigate these issues and improve the research landscape. In this primer, I explain how cognitive psychologists can implement preprints, preregistration, Registered Reports, and open materials, code, and data into their research workflow. I also outline how such training can be embedded into the higher education curriculum to facilitate these skills in students who represent the future of our discipline.
Grit Scale and its relationship with Positive Mental Health in young medical professional
Authors: Palencia-Sánchez Francisco , Blanco Laura M. Niño , Castellanos Valentina Ramírez , Villamil Santiago Andrade , Rendón-Garavito Ana M. , Arrázola Luisa , Riaño-Casallas Martha Isabel
Published: September 2024

Mental health in healthcare workers has been thoroughly studied throughout the years, besides perceived stress in this population constitutes a physical and psychological problem for these individuals. Different tools have been used to identify an individual's strengths to face daily activities to maintain emotional, psychological, and social well-being. Concepts such as Positive Mental Health and Grit have surged to characterize protective factors for mental health disorders. This study aimed to apply Lukat's Positive Mental Health scale and Duckworth's Grit Scale on fifth-year medical students, On the verge of becoming medical interns of the Pontificia Universidad Javeriana in Bogotá, Colombia, to evaluate if there is any correlation between the results of both instruments. The results suggested that women in our sample population had on average, less Grit and less Positive Mental Health Scale score than men. The association between the two variables was made through Pearson's correlation coefficient, revealing a weak positive association between Grit and Positive Mental Health in medical students. However, further research is needed to deepen our knowledge about this relationship. These findings reflect the importance of positive mental health and Grit in medical interns.
Exploring Entrepreneurial Success Factors in Nepal
Authors: Mishra A. K.
Published: September 2024

Entrepreneurship education plays a crucial role in fostering economic growth and competitiveness by providing individuals with the skills and knowledge necessary for success and innovation. Addressing educational needs, particularly in underserved regions, can significantly enhance entrepreneurial outcomes and contribute to broader economic development. Government policies and regulations profoundly impact business operations, competitiveness, and growth. It is essential for governments to continuously adapt their policies to create a conducive business environment and promote entrepreneurial development. The interplay between government policies and business performance underscores the importance of a well-coordinated approach to economic policy and entrepreneurship support. Effective policy frameworks are essential in supporting entrepreneurial activities and fostering a favorable business environment. The dynamic relationship between government actions and business success highlights the need for ongoing adaptation and coordination in economic policy to promote entrepreneurial development and economic growth.
Impact of Behavioral Biases Observed on Investors’ Performance in The Nepalese Stock Market
Authors: Aryal Sushrabya , Shrestha Kundan , Pradhan Jyotirmaya , Prajapati Grisha , Basnet Ayush
Published: September 2024

The purpose of this research article is to clarify how behavioral biases affect the performance of investors within the framework of the Nepalese stock market. This study employs a quantitative analysis utilizing a purposive and causal research design. Data was collected between April and May of 2024 through a survey conducted with 124 respondents who actively trade in the Nepalese stock market. Secondary data was gathered from existing research papers to support the findings. The analysis reveals that emotional biases, specifically Loss Aversion Bias and Overconfidence Bias, significantly impact investor performance. In contrast, cognitive biases, such as Anchoring Bias, Availability Bias, and Representativeness Bias, showed no significant effect on investor performance. This suggests that while cognitive biases can be identified and adapted, emotional biases may have a more profound influence on trading decisions. Implications the significance of this study extends beyond individual and institutional investors. It provides insights into the importance of understanding various biases that affect investor performance in the Nepalese context. By addressing these biases, investors can improve their decision-making processes and potentially enhance their investment outcomes. This research contributes to the existing literature on behavioral finance by focusing on the specific biases affecting Nepalese investors. It highlights the need for further exploration of these biases to mitigate inconsistencies in investor performance and promote more informed trading strategies in the Nepalese stock market.
O LÚDICO NA EDUCAÇÃO INFANTIL: ARTE, LITERATURA, BRINQUEDOS E BRINCADEIRAS
Authors: Oliveira Flávia Aparecida de , Bergamo Thelma Maria de Moura , Mariano Sangelita Miranda Franco
Published: September 2024

A educação infantil é fundamental para o desenvolvimento das crianças, proporcionando experiências enriquecedoras e oportunidades de socialização por meio de atividades lúdicas adaptadas as suas necessidades. A função do professor é acolher a criança, respeitar suas preferências e integrar elementos culturais e artísticos, mantendo-se atualizado para assegurar um ensino alinhado com princípios educacionais democráticos. O presente estudo tem como objetivo analisar a importância das atividades lúdicas e artísticas na educação infantil por meio de uma revisão bibliográfica realizada  utilizando descritores os conceitos de "Educação Infantil", "Arte", "Lúdico", "Literatura" e "Brincar", e incluiu artigos e livros publicados em português que abordam o tema. A literatura  estudada destaca que a literatura infantil, a arte e as brincadeiras são vitais para o desenvolvimento integral das crianças, estimulando a curiosidade, habilidades sociais e cognitivas.
MANAJEMEN RISIKO TEKNOLOGI INFORMASI PADA PT. HAGEN AMERSA VETA MENGGUNAKAN FRAMEWORK COBIT 5
Authors: Anindya Vinsensia Fereria , Aliyanto Arif
Published: September 2024

PT. Hagen Amersa Veta menerapkan Teknologi Informasi dalam proses bisnis untuk mencapai tujuan perusahaan. Namun, penggunaan Teknologi Informasi membawa risiko yang dapat menurunkan efektivitas dan efisiensi bisnis. Teknologi Informasi sangat penting. Saat ini, PT. Hagen Amersa Veta menghadapi beberapa masalah di divisi Teknologi Informasi, seperti risiko bugs pada program, kegagalan pembaruan data karena ukuran file yang tidak sesuai, dan human error dari pengguna. Di divisi lapangan, terdapat risiko kesalahan pada aplikasi untuk pengukuran jalan serta kesulitan dalam pelaporan kepada pembuatnya. Di divisi keuangan, terdapat risiko manipulasi data keuangan oleh staf perusahaan. Penelitian ini menganalisis manajemen risiko Teknologi Informasi di PT. Hagen Amersa Veta menggunakan framework COBIT 5 pada domain APO12 dalam subdomain APO12.01 hingga APO12.06.