bluuebunny/crossref_metadata_2025 huggingface dataset:
Work status changes and associated factors in a nationwide sample of Norwegian long-term breast cancer survivors
Authors: Bøhn Synne-Kristin Hoffart , Vandraas K. F. , Kiserud C. E. , Dahl A. A. , Thorsen L. , Ewertz M. , Lie H. C. , Falk R. , Reinertsen K. V.
Published: March 2022

Purpose

The study aims to describe work status at diagnosis and 8 years post-diagnosis in a nationwide sample of breast cancer survivors (BCSs), and investigate associated and self-reported factors of reduced work status.

Methods

Women aged 20–65 years when diagnosed with stage I–III breast cancer (BC) in 2011 or 2012 were invited to participate in a questionnaire study in 2019 (n = 2803), of whom 49% (n = 1361) responded. For this sub-study, we included 974 BCSs below the legal retirement age in Norway (< 67 years) at survey and with complete work status data. Reduced work status was defined as being in paid work at BC diagnosis and not working at time of survey. Logistic regression analyses were applied to identify factors associated with reduced work status.

Results

Of BCSs who were in paid work at diagnosis (n = 845), 63% maintained their work status to 8 years later. Reduced work status was associated with not living with children (OR .44, 95% CI .24–.82), age (OR 1.16, 95% CI 1.11–1.21), chemotherapy (OR 2.83, 95% CI 1.24–6.61), > 2 comorbid conditions (OR 2.27, 95% CI 1.16–4.32), cognitive function (OR .99, 95% CI .98–.99), fatigue (OR 1.02, 95% CI 1.01–1.03), and neuroticism (OR 1.57, 95% CI 1.00–2.46). BC and late effects were reported as reasons for reduced work status and disability.

Conclusions

The majority of BCSs who were in paid work at diagnosis were working 8 years later.

Implications for Cancer Survivors

Our results suggest a need to focus on fatigue and reduced cognitive function among long-term BCSs, with the ultimate aim of improving work sustainability.
Laparoscopic paediatric inguinal hernia repair: lessons learned from 102 cases
Authors: O’Brien Lukas , Hannan Enda , Hassett Sinead
Published: March 2022

Introduction

Paediatric inguinal hernias (IHs) are common. The first paediatric laparoscopic hernia repair was described by El-Gohary and colleagues in the United Arab Emirates in 1993. Both laparoscopic inguinal hernia repair (LIHR) and open repair still exist concurrently with no consensus on gold standard treatment at present. The purpose of this study was to retrospectively evaluate our initial experience with LIHR in paediatric patients.

Methods

A retrospective observational cohort study of all paediatric patients that underwent LIHR in our institution was performed. Intraoperative and postoperative outcomes were examined.

Results

During the study period, 102 patients were scheduled for LIHR. The majority (76.5%) were male with a median age of 5 months. Thirty two patients (31.4%) were neonates at the time of surgery. The majority of cases (83.3%) were elective procedures. There were no instances of intraoperative vascular or visceral injury. Most patients underwent surgery as a day case. Eighteen patients underwent bilateral LIHR. The recurrence rate was 1.9%. These occurred in the first two patients to undergo LIHR, after which no recurrences were observed following a modification of the technique. The overall complication rate was 7.1%, most of which were managed conservatively.

Conclusion

Paediatric LIHR is a safe, feasible and effective procedure that is associated with a short inpatient length of stay, a low recurrence rate and low postoperative complication rate. The technique is versatile and can be used to treat both elective and emergency presentations with IH in a wide age range.
Does Cannabidiol Have a Benefit as a Supportive Care Drug in Cancer?
Authors: Lord Sarah , Hardy Janet , Good Phillip
Published: March 2022

Opinion statement

Cannabinoids have been purported as having a wide range of therapeutic uses although currently, there is minimal evidence to support these claims. Patients with advanced cancer experience many distressing symptoms, with some turning to medicinal cannabis to help alleviate these. Focus has fallen on cannabidiol (CBD) as a potential treatment for a variety of symptoms in advanced cancer due to the lack of psychoactive side effects and the potential molecular mechanisms of action associated with this cannabinoid. Many cannabinoid products are easily available in the community, and more countries are legalizing or allowing over the counter products. Studies show that CBD is generally well tolerated, but there are many potential drug interactions that have not been well studied. Few studies have specifically looked at the role of CBD in treating cancer symptoms, with most focusing on combination cannabinoid products. There are currently many unknowns associated with CBD, including which symptoms it might be best for, appropriate dosing, and route of administration. This is especially important in advanced cancer where patients often have significant organ dysfunction and frailty that could impact on the pharmacology of CBD. A small pilot study has shown promise for a role of CBD in the psychological symptoms associated with advanced cancer. Further research is currently underway to further clarify the role of CBD in this setting and to understand how best it might help our patients. Currently we advocate that CBD be used in supervised clinical trials, so that efficacy and adverse effects can be closely monitored.
Innenansichten des medizinischen Kinderschutzes
Authors: Franzheld Tobias , Eckoldt-Wolke Felicitas
Published: March 2022

Im ersten Teil des Beitrags geht es um die Beschreibung der Thüringer Kinderschutz Ambulanz (TAKS) auf Grundlage von Fallzahlen und Merkmalen zu Kinderschutzfällen. Im zweiten Teil wird auf zentrale Prinzipien der Fallarbeit bei der Aufklärung von Gefährdungen eingegangen. Es wird davon ausgegangen, dass sich spezialisierte Einrichtungen wie die TAKS vor dem Hintergrund eines öffentlichen Interesses am Kinderschutz herausbilden und mit ihrem Angebotsprofil zur Aufklärung von Kindeswohlgefährdungen beitragen.
Characterization and modeling of the temperature-dependent thermal conductivity in sintered porous silicon-aluminum nanomaterials
Authors: Kojda Danny , Hofmann Tommy , Gostkowska-Lekner Natalia , Habicht Klaus
Published: March 2022

Nanostructured silicon and silicon-aluminum compounds are synthesized by a novel synthesis strategy based on spark plasma sintering (SPS) of silicon nanopowder, mesoporous silicon (pSi), and aluminum nanopowder. The interplay of metal-assisted crystallization and inherent porosity is exploited to largely suppress thermal conductivity. Morphology and temperature-dependent thermal conductivity studies allow us to elucidate the impact of porosity and nanostructure on the macroscopic heat transport. Analytic electron microscopy along with quantitative image analysis is applied to characterize the sample morphology in terms of domain size and interpore distance distributions. We demonstrate that nanostructured domains and high porosity can be maintained in densified mesoporous silicon samples. In contrast, strong grain growth is observed for sintered nanopowders under similar sintering conditions. We observe that aluminum agglomerations induce local grain growth, while aluminum diffusion is observed in porous silicon and dispersed nanoparticles. A detailed analysis of the measured thermal conductivity between 300 and 773 K allows us to distinguish the effect of reduced thermal conductivity caused by porosity from the reduction induced by phonon scattering at nanosized domains. With a modified Landauer/Lundstrom approach the relative thermal conductivity and the scattering length are extracted. The relative thermal conductivity confirms the applicability of Kirkpatrick’s effective medium theory. The extracted scattering lengths are in excellent agreement with the harmonic mean of log-normal distributed domain sizes and the interpore distances combined by Matthiessen’s rule.
Stories you cannot defeat! political myths as cultural integration and legitimation strategies of autocratic regimes
Authors: Rudolf Dennis Bastian
Published: March 2022

Given the worldwide stagnation or even regression of democratization processes, autocratic regimes continue to pose a challenge for political science. In this regard, the merit of an original research on autocracies primarily results from the fact that it has drawn attention to the core elements, modes, and logics of operation, as well as the manifold types of regimes. In explaining autocratic regime persistence and legitimation, however, the dominance of institutionalist and economic approaches has led to a shortening of a complex phenomenon. Especially the lack of cultural variables still represents an open flank, which can be partly attributed to systematic limits of knowledge and implementation problems of quantitative approaches in non-democratic contexts. To address this issue, the article proposes the analysis of political myths as an integration and legitimation strategy of autocratic regimes, which will be formulated conceptually as a qualitative approach to political culture research. As transcultural phenomena, political myths narratively articulate the otherwise abstract ideological foundations of the political community, the regime, and the authorities. Thus, in addition to examining myth as a political science phenomenon, a post-behaviorist reading of David Easton’s concept of political support is offered to relate the ideological aspects of narration to different regime types, power structures, and cultural contexts.
To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity
Authors: Gruber Elisabeth S. , Stadlbauer Vanessa , Pichler Verena , Resch-Fauster Katharina , Todorovic Andrea , Meisel Thomas C. , Trawoeger Sibylle , Hollóczki Oldamur , Turner Suzanne D. , Wadsak Wolfgang , Vethaak A. Dick , Kenner Lukas
Published: March 2022

Micro- and nanoplastics (MNPs) are recognized as emerging contaminants, especially in food, with unknown health significance. MNPs passing through the gastrointestinal tract have been brought in context with disruption of the gut microbiome. Several molecular mechanisms have been described to facilitate tissue uptake of MNPs, which then are involved in local inflammatory and immune responses. Furthermore, MNPs can act as potential transporters (“vectors”) of contaminants and as chemosensitizers for toxic substances (“Trojan Horse effect”). In this review, we summarize current multidisciplinary knowledge of ingested MNPs and their potential adverse health effects. We discuss new insights into analytical and molecular modeling tools to help us better understand the local deposition and uptake of MNPs that might drive carcinogenic signaling. We present bioethical insights to basically re-consider the “culture of consumerism.” Finally, we map out prominent research questions in accordance with the Sustainable Development Goals of the United Nations.
Origin and fate of the greatest accumulation of silver in ancient history
Authors: Blichert-Toft Janne , de Callataÿ François , Télouk Philippe , Albarède Francis
Published: March 2022

The capture of the Achaemenid treasuries in 331–330 BCE by Alexander the Great in Persepolis and Susa marked the demise of the 300-year-old Persian Empire and the advent of Hellenistic kingdoms. Alexander seized the equivalent of about 5000 tons of silver, which represented the accumulated tributes paid by subjugated people from the Aegean Sea to the Indus to their Achaemenid rulers. Die studies show that this gigantic amount of silver, the so-called Persian mix, had been used to produce most of the coinage of Alexander the Great himself and to an even greater extent those of the Diadochi, his successors. What remains to be understood is the origin of the silver of this immense treasure. Lead isotope abundances determined on both Persian sigloi and alexanders struck from Achaemenid silver trace the bullion source to the southern Aegean, Macedonia, and Thrace. Lead in pseudo-coinage from early Indian kingdoms is isotopically different from the rest, which attests to a limited Indian contribution to the Achaemenid treasuries. Studies of Iron Age hoards from the Levant leave open the possibility that the making of the Persian mix may have predated the Achaemenid expansion of the seventh century BCE. We speculate on the motivations of such massive hoarding by the Persian kings and on its economic implications.
How does multiannual plastic mulching in strawberry cultivation influence soil fungi and mycotoxin occurrence in soil?
Authors: Meyer Maximilian , Schaumann Gabriele Ellen , Muñoz Katherine
Published: March 2022

The production of mycotoxins is often interpreted as fungal response to cope with unfavorable growth conditions induced by toxic substances, environmental and biological factors. Soil covers influence soil environment, which consequently can change the abundance and composition of microbial communities. We investigated how plastic coverage (PC) influence soil fungi and mycotoxin occurrence (deoxynivalenol, nivalenol and zearalenone) compared to the traditional straw coverage (SC) in dependence of soil depth and time in a 3-year field experiment in strawberry cultivation. In total, 300 soil samples, resulting from two treatments, three soil layers, and ten sampling dates (n = 5), were analyzed for mycotoxins and ergosterol (proxy for soil fungal biomass) with liquid chromatography high resolution mass spectrometry and high-performance liquid chromatography with UV-detection, respectively. The modified microclimate under PC had no significant influence on fungal biomass, whereas SC promoted fungal biomass in the topsoil due to C-input. Mycotoxins were detected under both cover types in concentrations between 0.3 and 21.8 µg kg−1, mainly during strawberry establishment period and after fungicide application. Deoxynivalenol had the highest detection frequency with 26.3% (nivalenol: 8.3%, zearalenone: 8.7%). This study confirmed the in situ production of mycotoxins in soil, which seems mainly triggered by field treatment (fungicide application) and plant growth stage (establishment period) rather than on mulching type. Further investigations are necessary to better understand the influence of different agricultural practices and soil types on the production and fate of mycotoxins.
Gendering post-harvest loss research: responsibilities of women and men to manage maize after harvest in southwestern Ethiopia
Authors: Lelea Margareta Amy , Garbaba Chemeda Abedeta , Guluma Abera , Hensel Oliver
Published: March 2022

Post-harvest losses are a significant problem worldwide, leading to a waste of resources when they are becoming scarcer. Rather than putting more energy into increasing production volume, addressing post-harvest losses can increase food availability without increasing yields. Using maize in Ethiopia to introduce gendering post-harvest loss research, we analyze the gendered division of labor in post-harvest management and then discuss implications. The study was conducted from 2014–2015 in southwestern Ethiopia as part of a broader research project from 2013–2018. Semi-structured interviews were conducted with 208 male and female farmer heads of household. Our results show that although maize post-harvest activities are deemed to be the responsibility of women, the overall management of maize after harvest requires the cooperation of all household members. For example, both women and men contribute to time-sensitive harvest, packing and de-husking activities. Men tend to have the responsibility for ensuring that maize is stored well. Critically, women tend to sell small quantities of maize to pay for everyday household expenses including purchasing other foods to diversify diets. Often recommendations in literature to reduce maize post-harvest losses include building processing centers and formalizing the supply chain. However, as shown in this research, women’s role to decide which maize to consume in the home and which to sell is important for access to quality food. Without gendering post-harvest loss research, it is possible that gender harms are enacted when women’s livelihoods are impacted in the process of reducing post-harvest losses, and this may compromise food security.
Unpacking pathways to diversified livelihoods from projects in Pacific Island coastal fisheries
Authors: Roscher Matthew B. , Eriksson Hampus , Harohau Daykin , Mauli Senoveva , Kaltavara Jeremie , Boonstra Wiebren J. , van der Ploeg Jan
Published: March 2022

Livelihood diversification has become an integral focus of policies and investments aiming to reduce poverty, vulnerability, and pressure on fishery resources in coastal communities around the globe. In this regard, coastal fisheries in the Pacific Islands have long been a sector where livelihood diversification has featured prominently. Yet, despite the widespread promotion and international investment in this strategy, the ability of externally funded livelihood diversification projects to facilitate improved resource management and rural development outcomes often remains inconsistent. We argue these inconsistencies can be attributed to a conceptual ambiguity stemming from a lack of attention and awareness to the complexity of livelihood diversification. There is still much to learn about the process of livelihood diversification, both in its theoretical conceptualizations and its practical applications. Herein, we utilize a common diversity framework to clarify some of this ambiguity by distinguishing three diversification pathways. These pathways are illustrated using an ideal–typical Pacific Island coastal household and supported by examples provided in the literature that detail livelihood diversification projects in the Pacific. Through this perspective, we seek a more nuanced understanding of what is meant within the policy and practice goal of livelihood diversification. Thereby enabling more targeted and deliberate planning for development investments that facilitates outcomes in support of sustainable livelihoods.
Impact of teachers’ professional learning on students’ learning of multiplicative thinking
Authors: Downton Ann , Giumelli Kerry , McHugh Barbara , Stenning Paul
Published: March 2022

The shift from additive to multiplicative thinking is challenging for students. A professional learning program was developed that focused on an identified area of need by teachers, namely multiplicative thinking. Program content focused on concepts underpinning multiplicative thinking, pedagogical approaches, challenging tasks, and application to classroom practice. It was delivered via six 90-min modules in 13 participating schools across terms 2–4, as part of regular after school professional learning. Whilst all staff participated, the research focus was year 3–4 teachers. Students’ historical data were collected across four years (2016–2019) to determine mean growth over time, in participating and non-participating schools. National Assessment Program Literacy and Numeracy (NAPLAN) and Mathematics Assessment Interview (MAI) data were used to determine the impact of the learning, as both assessments are administered annually. Analysis of year 4 students’ longitudinal data showed greater mean growth in student learning over a 2-year period in schools involved in the learning and additional in-class coaching support, than students in non-participating schools. Our findings showed that targeted school-based professional learning, with in-class support from a knowledgeable other, leads to teachers’ improved understanding of multiplicative thinking and subsequent pedagogical content knowledge to support student learning.
Variation in the seasonality of the respiratory syncytial virus during the COVID-19 pandemic
Authors: Bermúdez Barrezueta Lorena , Matías Del Pozo Vanesa , López-Casillas Pablo , Brezmes Raposo Marta , Gutiérrez Zamorano María , Pino Vázquez María de la Asunción
Published: March 2022

Background

The COVID-19 pandemic has caused a variation in the circulation of common respiratory viruses. Our objective was to analyse the epidemiology of respiratory syncytial virus (RSV) bronchiolitis admissions during the COVID-19 pandemic in comparison with previous epidemic seasons.

Methods

We conducted an observational study involving infants with RSV bronchiolitis admitted to a tertiary hospital during two periods: pandemic COVID-19 (15 March 2020–30 September 2021) and pre-pandemic (1 October 2014–14 March 2020). Demographic and clinical characteristics were collected.

Results

A total of 270 patients were admitted for RSV bronchiolitis: 253 in the pre-pandemic period with an average of 42 admissions per season vs 17 in the pandemic. During the pandemic, the RSV outbreak started late in June 2021 with a higher percentage of prematurity and PICU admissions.

Conclusion

A change in RSV seasonality was observed during the COVID-19 pandemic, with an unusual outbreak in summer 2021 of lower magnitude than previous seasons.
Realizing enhanced energy storage and hardness performances in 0.90NaNbO3−0.10Bi(Zn0.5Sn0.5)O3 ceramics
Authors: Dong Xiaoyan , Li Xu , Chen Hongyun , Dong Qinpeng , Wang Jiaming , Wang Xiang , Pan Yue , Chen Xiuli , Zhou Huanfu
Published: March 2022

Ceramic dielectric capacitors have a broad scope of application in pulsed power supply devices. Relaxor behavior has manifested decent energy storage capabilities in dielectric materials due to its fast polarization response. In addition, an ultrahigh energy storage density can also be achieved in NaNbO3 (NN)-based ceramics by combining antiferroelectric and relaxor characteristics. Most of the existing reports about lead-free dielectric ceramics, nevertheless, still lack the relevant research about domain evolution and relaxor behavior. Therefore, a novel lead-free solid solution, (1−x)NaNbO3−xBi(Zn0.5Sn0.5)O3 (abbreviated as xBZS, x = 0.05, 0.10, 0.15, and 0.20) was designed to analyze the domain evolution and relaxor behavior. Domain evolutions in xBZS ceramics confirmed the contribution of the relaxor behavior to their decent energy storage characteristics caused by the fast polarization rotation according to the low energy barrier of polar nanoregions (PNRs). Consequently, a high energy storage density of 3.14 J/cm3 and energy efficiency of 83.30% are simultaneously available with 0.10BZS ceramics, together with stable energy storage properties over a large temperature range (20–100 °C) and a wide frequency range (1–200 Hz). Additionally, for practical applications, the 0.10BZS ceramics display a high discharge energy storage density (Wdis ≈ 1.05 J/cm3), fast discharge rate (t0.9 ≈ 60.60 ns), and high hardness (H ≈ 5.49 GPa). This study offers significant insights on the mechanisms of high performance lead-free ceramic energy storage materials.
Instructional Design Strategies for Teaching the Mental Status Examination and Psychiatric Interview: a Scoping Review
Authors: Lenouvel Eric , Chivu Camelia , Mattson Janet , Young John Q. , Klöppel Stefan , Pinilla Severin
Published: March 2022

Objective

The psychiatric mental status examination is a fundamental aspect of the psychiatric clinical interview. However, despite its importance, little emphasis has been given to evidence-based instructional design. Therefore, this review summarizes the literature from an instructional design perspective with the aim of uncovering design strategies that have been used for teaching the psychiatric interview and mental status examination to health professionals.

Methods

The authors conducted a scoping review. Multiple databases, reference lists, and the gray literature were searched for relevant publications across educational levels and professions. A cognitive task analysis and an instructional design framework was used to summarize and chart the findings.

Results

A total of 61 articles from 17 countries in six disciplines and three educational levels were identified for data extraction and analysis. Most studies were from the USA, presented as educational case reports, and carried out in undergraduate education in the field of psychiatry. Few articles described the instructional rationale for their curriculum. None of the studies compared the effectiveness of different instructional design components. Reported learning activities for each task domain (knowledge, skills, and attitudes) and for each step of an instructional design process were charted. Most articles reported the use of introductory seminars or lectures in combination with digital learning material (videos and virtual patients in more recent publications) and role-play exercises.

Conclusions

Educators in psychiatry should consider all task domains of the psychiatric interview and mental status examination. Currently, there is a lack of empirical research on expertise acquisition and use of instructional design frameworks in this context.
Developing Leadership Skills in Pharmacy Education
Authors: Ali Raja , Alnaimi Shaikha Jabor , Abdulrhim Sara , Mraiche Fatima
Published: March 2022

Leadership could refer to holding official leadership positions or advocating for patients and the profession. Different pharmacy organizations recommend the inclusion of leadership development in pharmacy education and as such some pharmacy schools have introduced courses or various initiatives which support the development of leadership skills. In this commentary, we discuss means by which various pharmacy schools incorporate ways to develop leadership skills. This commentary also addresses the competencies used to assess leadership skills in pharmacy education.
A multi-attribute approach to ranking departments based on performance: a balanced scorecard pilot study
Authors: Şenel Uğur Tahsin , Rouyendegh Babak Daneshvar , Demir Sercan
Published: March 2022

Departments are assessed using performance evaluation systems (PES) based on their important performance criteria. The sum of the weighted KPIs’ actualization scores creates the departments' performance ratings, which are used to rank departments from highest to lowest performing. However, this strategy does not account for departmental variances. We used multi-attribute decision-making (MADM) techniques in this study to ascertain the performance of several divisions inside a business. Our study's structure is divided into two distinct parts. In the first stage, pair-wise evaluation matrices are built and attribute weights are established using the Analytic Hierarchical Process (AHP) to determine attribute precedence. The second step employs the Elimination and Choice Expressing the Reality (ELECTRE) methodology to rank the departments using the attribute weights generated in the first stage using the AHP method. At the conclusion of the paper, a case study is presented to demonstrate how departments are organized in accordance with performance management principles within a corporation that use the balance-scorecard program for performance evaluation.
CFD modeling and laboratory studies of dust cleaning efficacy of an efficient four stage non-clogging impingement filter for flooded-bed dust scrubbers
Authors: Kumar Ashish Ranjan , Gupta Neeraj , Schafrik Steven
Published: March 2022

Fibrous-type filters are used to capture dust particles in mining and other occupations where personnel are exposed for prolonged periods. Dust cleansing devices including flooded-bed dust scrubbers use these mesh-type multi-layered filters. These filters trap dust particles efficiently on their surface and inside their mesh. However, their continued operation leads to dust build-up and clogging. This results in increased resistance of the filter and lowered airflow rate through the scrubber. This could potentially enhance the exposure of the miners. A non-clogging self-cleaning impingement screen type dust filter was designed by the authors for use in mining and industrial dust cleansing applications. The filter guides dirt-laden air through rapidly turning paths which forces it to shed heavier particles. The particles impact one of the impermeable solid metallic filter surfaces and are removed from the airstream. A full cone water spray installed upstream prevents any surface build-up of dust. This paper summaried the computer models generated to show the filter operations and laboratory experiments including optical particle counting to establish the cleaning efficiency.
Magnus Effect over Aerodynamic Components of Spinning Missile
Authors: Gao Yi , Lei Juanmian , Yin Jintao
Published: March 2022

To reveal the flow mechanism of the Magnus effect of the spinning missile, the flow field under supersonic conditions was numerically simulated based on the unsteady Reynolds-time-averaged Navier–Stokes equation, and the implicit dual-time stepping method and sliding mesh method were used. Validation was performed to ensure the reliability of the numerical methods. The results of the numerical simulation and the wind-tunnel experimental data coincided quite well. The aerodynamic characteristics of various configurations while spinning were calculated. The effect of aerodynamic components and aerodynamic interference between components on the Magnus effect were analyzed. The results indicate that for the projectile body, the interference of the canard enlarges the time-averaged side force; when the slenderness ratio becomes large, from the view of the base, the left leeward separation vortex is close to the surface, resulting in a low-pressure region, and the direction of the side force and yawing moment are changed. The fin installation angle can weaken the body Magnus effect to some extent. For the projectile fin, the influence of leeward separation vortices on the fin depends on their relative positions. The fin installation angle can weaken and even cause the reversal of the side force direction.
Sell now or later? A decision-making model for feeder cattle selling
Authors: Yan Minhao , Schmit Todd M. , Baker Michael J. , LeRoux Matthew N. , Gómez Miguel I.
Published: March 2022

Given the relatively small industry scale of cow-calf operations in New York to other regions of the country, little is known about differences in determinant values for feeder cattle. Using auction prices and quality characteristics over 7 years, differences in market, lot, and quality parameters suggest opportunities for improved marketing performance. A delta profit model is constructed to inform timing of marketing decisions for producers. The results indicate a relatively high potential for producers to increase farm returns by delaying sales of lighter-weight feeder cattle from the fall to spring auction months, given sufficient rates of gain and reasonable overwintering costs.
El “otro lado” de la historia: Patrimonio arqueológico y procesos de memoria
Authors: Salerno Virginia M. , Cañardo Lorena
Published: March 2022

En este trabajo se explora la organización de un taller de cerámica indígena ubicado en el interior de la provincia de Buenos Aires. Este taller fue impulsado por una familia que incursionó sobre técnicas de alfarería indígenas a partir del hallazgo fortuito de fragmentos de cerámica arqueológica. Desde un enfoque biográfico, analizamos las prácticas desplegadas en torno a la cerámica arqueológica que dieron lugar a procesos de memoria indígena. Luego, reflexionamos sobre la dimensión política de los procesos movilizados y el modo en que los mismos interpelan la gestión del patrimonio arqueológico local. A partir de ello se abordan las tensiones que configuran el saber científico académico respecto del patrimonio y la cerámica arqueológica. Con la presentación de este caso se busca aportar al debate sobre los múltiples procesos sociales que los objetos arqueológicos pueden movilizar a nivel local, involucrando una trama compleja de actores e instituciones.
Deconstructing Glass and Building up Shards at the Early Royal Society
Authors: Ezra Ruth
Published: March 2022

In 1662, the physician Christopher Merret presented his fellow members of the Royal Society with an English translation of Antonio Neri's “L'arte vetraria” (The art of glass, 1612). Central to the preparation and receipt of this book was a cache of objects relevant to glassmaking, now lost or dispersed. These materia vitraria served as a tangible appendix to Merret's written commentary. They also reified the society's interest in the development of domestic industry by offering a direct means by which fellows could appreciate the raw materials of contemporary glassmaking alongside evidence of the trade's longer history in the British Isles.
Nābulusī Explores the Ruins of Baalbek: Antiquarianism in the Ottoman Empire during the Seventeenth Century
Authors: Shafir Nir
Published: March 2022

Although it is generally thought that Muslims paid little attention to pre-Islamic antiquity, the Damascene scholar ʿAbd al-Ghanī al-Nābulusī visited and described the Roman ruins of Baalbek twice, in 1689 and 1700. He interpreted the site, however, not as a temple but as a palace built by jinns for Solomon. Nābulusī was very likely aware of the site's Roman past but purposefully played with its historicity to highlight Syria's innate sanctity. His interpretation of Baalbek reveals an antiquarian project in the Ottoman Empire that was constructed along variant but parallel lines to the better known one in Renaissance Europe.
Richard Rorty and the Demands of Liberalism
Authors: LAMB ROBERT
Published: March 2022

In this article, I show that Richard Rorty’s unduly neglected normative political theory advances a far more distinct and demanding form of liberalism than is usually attributed to him. Attention to how Rorty understands solidarity—and its corresponding conception of public obligations—encourages analysis of his nonjuridical vision of liberal community. Through examination of his oft-ignored, revealing interpretation of Vladimir Nabokov and instructive comparison with the thought of Judith Shklar, I argue that, for Rorty, the sustainability of a liberal community requires an ethos of curiosity, whereby citizens feel moved to uncover and understand the personal experiences of cruelty and humiliation endured by others. We can make sense of this ethos and its demands of us through rethinking the idea of political conversation. This understanding of Rorty’s intellectual project not only enriches our appreciation of his complex political theory but also contests the meaning and implications of liberalism itself.
Geochemistry and new zircon U–Pb geochronology of Mesoproterozoic Punugodu granite pluton, SE India: implications for anorogenic magmatism along the western margin of Nellore Schist Belt, India
Authors: Narshimha Ch. , Sesha Sai V. V. , Reddy U. V. B. , Vijaya Kumar T. , Babu E. V. S. S. K. , Sreenivas B. , Subramanyam K. S. V.
Published: March 2022

We report a new zircon U–Pb age of 1257 ± 6 Ma for the Punugodu granite (PG) pluton in the Eastern Dharwar Craton (EDC), Southern India. The Mesoproterozoic PG is alkali feldspar hypersolvus granite emplaced at shallow crustal level, as evident from the presence of rhyodacite xenoliths and hornfelsic texture developed in the metavolcanic country rocks of the Neoarchaean Nellore Schist Belt (NSB). Geochemically, the PG is metaluminous, ferroan and alkali-calcic, and is characterized by high SiO2 and Na2O + K2O, Ga/Al ratios >2.6, high-field-strength elements and rare earth element (REE) contents with low CaO, MgO and Sr, indicating its similarity to anorogenic, alkali (A-type) granite. The highly fractionated REE patterns with negative europium anomalies of PG reflect its evolved nature and feldspar fractionation. Mafic (MME) to hybrid (HME) microgranular enclaves represent distinct batches of mantle-derived magmas that interacted, mingled and undercooled within the partly crystalline PG host magma. Felsic microgranular enclaves (FME) having similar mineralogical and geochemical characteristics to the host PG most likely represent fragments of marginal rock facies of the PG pluton. The PG appears to be formed from an oceanic island basalt (OIB)-like source in an anorogenic, within-plate setting. The emplacement of PG (c. 1257 Ma) in the vicinity of Mesoproterozoic Kanigiri Ophiolite (c. 1334 Ma) shows an age gap of nearly 77 Ma, which probably suggests PG emplacement in an extensional environment along a terrain boundary at the western margin of the Neoarchaean NSB in the EDC.
ONE STEP FORWARD, TWO STEPS BACK? INTERPRETING ‘PARTICULAR SOCIAL GROUP’ IN THE EUROPEAN UNION
Authors: Querton Christel
Published: March 2022

The article tests the claim of feminist scholars that concerns about gender have been marginalised in refugee law, by exploring the interpretation given to the concept of a ‘Particular Social Group’ set out in the 1951 Refugee Convention. It is argued that recent practice at the supranational level in the European Union has contributed to the deterioration of refugee protection standards for women seeking asylum from gender-based violence. However, the article demonstrates that a human rights-based approach to the interpretation of ‘Particular Social Group’, which is supported by extensive examples of good practice in individual Member States, has the potential to redress this.
Resting state connectivity predictors of symptom change during gaze-contingent music reward therapy of social anxiety disorder
Authors: Zhu Xi , Lazarov Amit , Dolan Sarah , Bar-Haim Yair , Dillon Daniel G , Pizzagalli Diego A , Schneier Franklin
Published: March 2022

Background

Social anxiety disorder (SAD) is common, first-line treatments are often only partially effective, and reliable predictors of treatment response are lacking. Here, we assessed resting state functional connectivity (rsFC) at pre-treatment and during early treatment as a potential predictor of response to a novel attention bias modification procedure, gaze-contingent music reward therapy (GC-MRT).

Methods

Thirty-two adults with SAD were treated with GC-MRT. rsFC was assessed with multi-voxel pattern analysis of fMRI at pre-treatment and after 2–3 weeks. For comparison, 20 healthy control (HC) participants without treatment were assessed twice for rsFC over the same time period. All SAD participants underwent clinical evaluation at pre-treatment, early-treatment (week 2–3), and post-treatment.

Results

SAD and depressive symptoms improved significantly from pre-treatment to post-treatment. After 2–3 weeks of treatment, decreased connectivity between the executive control network (ECN) and salience network (SN), and increased connectivity within the ECN predicted improvement in SAD and depressive symptoms at week 8. Increased connectivity between the ECN and default mode network (DMN) predicted greater improvement in SAD but not depressive symptoms at week 8. Connectivity within the DMN decreased significantly after 2–3 weeks of treatment in the SAD group, while no changes were found in HC over the same time interval.

Conclusion

We identified early changes in rsFC during a course of GC-MRT for SAD that predicted symptom change. Connectivity changes within the ECN, ECN-DMN, and ECN-SN may be related to mechanisms underlying the clinical effects of GC-MRT and warrant further study in controlled trials.
Local positioning system as a classic alternative to atomic navigation
Authors: Dubetsky B.
Published: March 2022

A local positional system (LPS) is proposed, in which particles are launched at given velocities, and a sensor system measures the trajectory of the particles in the platform frame. These measurements allow us to restore the position and orientation of the platform in the frame of the rotating Earth, without solving navigation equations. When the platform velocity is known and if the platform orientation stays the same, the LPS technique allows a navigational accuracy of 100 $\mu$m per one hour to be achieved. In this case, the LPS technique is insensitive to the type of platform trajectory. If there are also velocimeters installed on the platform, then one can restore the platform velocity and angular rate of the platform rotation with respect to the Earth. Instead of navigational equations, it is necessary to obtain the classical trajectory of a particle in the field of a rotating gravity source. Taking into account the gravity-gradient, Coriolis, and centrifugal forces, the exact expression for this trajectory is derived, which can be widely used in atomic interferometry. A new iterative method for restoring the orientation of the platform without using gyroscopes is developed. The simulation allows us to determine the conditions under which the LPS navigation error per hour is approximately $10$ m.
Is Living with Persons with Dementia and Depression Correlated to Impacts on Caregivers? A Scoping Review
Authors: Subota Ann , Spotswood Neve , Roach Maddy , Goodarzi Zahra , Holroyd-Leduc Jayna
Published: March 2022

Caregivers of persons with dementia and depression experience adverse effects associated with their role. The aim of this scoping review was to identify the challenges faced by caregivers of people with dementia and depression, along with interventions to support them. The MEDLINE®, Embase and PsycINFO databases were searched using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method. Grey literature was assessed using the Canadian Agency for Drugs and Technologies in Health’s Gray Matter tool.

The population consisted of caregivers of people with dementia and depression; the concept was to identify the negative impacts that caregivers experience and whether there are interventions to reduce them; the context was any study design targeting family or friends who were caregivers. A total of 12,835 citations were identified; 139 studies were included. Dementia and depression have variable impacts on outcomes experienced by caregivers, including burden/strain (n = 52), depression (n = 27), distress (n = 53), quality of life (n = 5) and health/well-being (n = 9). Pharmacological and non-pharmacological interventions have mixed effects. This study is important considering that depression in people with dementia is associated with caregiver distress. The use of a variety of non-pharmacological interventions could be beneficial to the latter.
Dynamics of specific antibodies in COVID-19 patients after recovery
Authors: Deng Zhi-Bo , Cheng Feng , Zhang Yong
Published: March 2022

The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an unprecedented global public health crisis. The objectives of this study were to analyse the dynamic trend in specific antibodies in the serum of patients infected with SARS-CoV-2 within 12 months after recovery and to make a preliminary assessment of the protective effect of vaccination. Eighty-seven patients with confirmed COVID-19 who were admitted to our hospital from January to February 2020 were followed after recovery. Three-millilitre blood samples were collected for specific antibody detection at four time points: 1, 6 and 12 months after recovery and 1 month after vaccination. The changes in specific immunoglobulin G (IgG) antibody and total antibody levels over 12 months were analysed. Moreover, an independent comparison of the neutralising antibody levels of patients after vaccination with those of healthy medical staff after vaccination was performed to compare the inhibition rates of the neutralising antibody to the virus. No statistically significant difference in the sex distribution between groups was observed (P > 0.05). Older patients had a greater risk of developing severe and critical COVID-19 (P < 0.05). The percentages of subjects positive for IgG antibodies at 1, 6 and 12 months after recovery were 88.5%, 75.9% and 50.6%, respectively. The rate of IgG antibody conversion from positive to negative was not uniform across time points: the change was slow in the first 6 months but increased significantly in the last 6 months (P < 0.05). The positive rate of critically ill patients in the first 6 months was 100.0%. The trend over time in total antibody levels was similar to that of IgG antibody levels. Over 12 months, the sample/cut off value of total antibodies continued to decrease, while that of different disease severities was significantly different (P < 0.05). After vaccine administration, the total antibody level exceeded the detection level in the first month, which was independent of disease severity (P > 0.05). Significant differences were observed in the inhibition rate of the neutralising antibody against the virus in the disease group and the control group (P < 0.05). IgG antibody produced by patients naturally infected with SARS-CoV-2 has a duration of no less than 1 year, and the change trend graph of total antibody levels was the same as that of IgG antibody levels. Under vaccine stimulation, the positive rate of IgG antibody was as high as 100%, and the total antibody concentration reached the highest level, which was independent of disease severity. Neutralising antibodies following vaccination in patients who recovered from COVID-19 had a higher inhibition rate against SARS-CoV-2 than those of vaccinated healthy controls, indicating that these COVID-19 patients had a lower risk of reinfection and were better protected.
Measuring early life adversity: A dimensional approach
Authors: Berman Ilana S. , McLaughlin Katie A. , Tottenham Nim , Godfrey Keith , Seeman Teresa , Loucks Eric , Suomi Stephen , Danese Andrea , Sheridan Margaret A.
Published: March 2022

Exposure to adversity in childhood is associated with elevations in numerous physical and mental health outcomes across the life course. The biological embedding of early experience during periods of developmental plasticity is one pathway that contributes to these associations. Dimensional models specify mechanistic pathways linking different dimensions of adversity to health and well-being outcomes later in life. While findings from existing studies testing these dimensions have provided promising preliminary support for these models, less agreement exists about how to measure the experiences that comprise each dimension. Here, we review existing approaches to measuring two dimensions of adversity: threat and deprivation. We recommend specific measures for measuring these constructs and, when possible, document when the same measure can be used by different reporters and across the lifespan to maximize the utility with which these recommendations can be applied. Through this approach, we hope to stimulate progress in understanding how particular dimensions of early environmental experience contribute to lifelong health.
Ontogenesis of Resin Ducts and Secretory Process in Protium spruceanum (Burseraceae) Stems
Authors: Bruzinga Wanessa Stéfanne de Jesus Silva , Ribeiro Leonardo Monteiro , Nunes Yule Roberta Ferreira , Pimenta Lúcia Pinheiro Santos , Almeida Mariana Araujo Thibau de , Mendes Martha Grasielle Alves , Mercadante-Simões Maria Olívia
Published: March 2022

The objective of this work was to characterize the ontogenesis of Protium spruceanum secretory ducts, to evaluate the effects of seasonality on that process, and to characterize the chemical nature of the resin. Morphometric, anatomical, micromorphometric, histochemical, and ultrastructural evaluations of shoot apexes and chemical analyses of the resin were performed. The ducts of schizolysigenous origin are distributed in the primary and secondary phloem. The subsecretory tissue is meristematic and can restore the secretory epithelium. Secretory epithelial cells have wall thickening resembling that of the Casparian strip that regulates secretion reflux. The main resin compounds are pentacyclic triterpenoids, α- and β-amyrins, and α- and β-amyrenones, which are reported here for the first time for this species. The presence of electron-dense and electron-opaque structures, in the secretory epithelial cells, are compatible with the triterpenes and mucilage identified in the resin. Rising temperatures, rainfall, and increasing day length induce the formation of ducts in the vascular cambium throughout Spring/Summer. The abundant production of resin rich in pentacyclic triterpenes indicates the potential use of the species for medicinal and cosmetic purposes. The understanding that secretory processes are concentrated during the Spring/Summer seasons will contribute to the definition of resin extraction management strategies.