bluuebunny/crossref_metadata_2025 huggingface dataset:
Modifications to Infant Formula Instructions Improve the Accuracy of Formula Dispensing
Authors: Gilmore Linda A. , Altazan Abby D. , Flanagan Emily W. , Beyer Alexandra G. , Olson Kelsey N. , O’Connell Alexis A. , Nguyen Timothy H. , Beyl Robbie A. , Redman Leanne M.
Published: April 2020

Readability of infant formula preparation instructions is universally poor, which may result in inaccurate infant feeding. Given that inaccurate formula dispensing can lead to altered infant growth and increased adiposity, there is an increased need for easy to follow instructions for formula preparation. We hypothesize that altering infant formula instruction labels using feedback from iterative focus groups will improve the preparation accuracy of powdered infant formula in a randomized controlled trial. Participants were recruited from the community, 18 years of age or older, willing to disclose demographic information for focus group matching, and willing to participate freely in the first (n = 21) or second (n = 150) phase of the study. In the second phase, participants were randomized to use the standard manufacturer instructions or to use the modified instructions created in the first phase. Accuracy was defined as the percent error between manufacturer-intended powder formula quantity and the amount dispensed by the participant. Participants who were assigned to the modified instructions were able to dispense the powdered formula more accurately than participants who used the standard manufacturer instructions (−0.67 ± 0.76 vs. −4.66 ± 0.74% error; p < 0.0001). Accuracy in powdered formula dispensing was influenced by bottle size (p = 0.02) but not by body mass index (p = 0.17), education level (p = 0.75), income (p = 0.7), age (p = 0.89) or caregiver status (p = 0.18). Percent error of water measurement was not different between the groups (standard: −1.4 ± 0.6 vs. modified: 0.7 ± 0.6%; p = 0.38). Thus, caloric density was more accurate in the modified instructions group compared to the standard manufacturer instructions group (−0.3 ± 0.6 vs.−2.9 ± 0.9%; p = 0.03). Infant formula label modifications using focus group feedback increased infant formula preparation accuracy.
Correction: McLoughlin, E.C.; O’Boyle, N.M. Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review. Pharmaceuticals 2020, 13, 8
Authors: McLoughlin Eavan C. , O’Boyle Niamh M.
Published: April 2020

We, the authors, wish to make the following corrections to our paper [...]
Quality by Design Optimization of Cold Sonochemical Synthesis of Zidovudine-Lamivudine Nanosuspensions
Authors: Witika Bwalya A. , Smith Vincent J. , Walker Roderick B.
Published: April 2020

Lamivudine (3TC) and zidovudine (AZT) are antiviral agents used to manage HIV/AIDS infection. The compounds require frequent dosing, exhibit unpredictable bioavailability and a side effect profile that includes hepato- and haema-toxicity. A novel pseudo one-solvent bottom-up approach and Design of Experiments using sodium dodecyl sulphate (SDS) and α-tocopheryl polyethylene glycol succinate 1000 (TPGS 1000) to electrosterically stablize the nano co-crystals was used to develop, produce and optimize 3TC and AZT nano co-crystals. Equimolar solutions of 3TC in surfactant dissolved in de-ionised water and AZT in methanol were rapidly injected into a vessel and sonicated at 4 °C. The resultant suspensions were characterized using a Zetasizer and the particle size, polydispersity index and Zeta potential determined. Optimization of the nanosuspensions was conducted using a Central Composite Design to produce nano co-crystals with specific identified and desirable Critical Quality Attributes including particle size (PS) < 1000 nm, polydispersity index (PDI) < 0.500 and Zeta potential (ZP) < −30mV. Further characterization was undertaken using Fourier Transform infrared spectroscopy, energy dispersive X-ray spectroscopy, differential scanning calorimetry, powder X-ray diffraction and transmission electron microscopy. In vitro cytotoxicity studies revealed that the optimized nano co-crystals reduced the toxicity of AZT and 3TC to HeLa cells.
Anticrystal Engineering of Ketoprofen and Ester Local Anesthetics: Ionic Liquids or Deep Eutectic Mixtures?
Authors: Umerska Anita , Bialek Klaudia , Zotova Julija , Skotnicki Marcin , Tajber Lidia
Published: April 2020

Ionic liquids (ILs) and deep eutectic mixtures (DEMs) are potential solutions to the problems of low solubility, polymorphism, and low bioavailability of drugs. The aim of this work was to develop and investigate ketoprofen (KET)-based ILs/DEMs containing an ester local anesthetic (LA): benzocaine (BEN), procaine (PRO) and tetracaine (TET) as the second component. ILs/DEMs were prepared via a mechanosynthetic process that involved the mixing of KET with an LA in a range of molar ratios and applying a thermal treatment. After heating above the melting point and quench cooling, the formation of supercooled liquids with Tgs that were dependent on the composition was observed for all KET-LA mixtures with exception of that containing 95 mol% of BEN. The KET-LA mixtures containing either ≥ 60 mol% BEN or 95 mol% of TET showed crystallization to BEN and TET, respectively, during either cooling or second heating. KET decreased the crystallization tendency of BEN and TET and increased their glass-forming ability. The KET-PRO systems showed good glass-forming ability and did not crystallize either during the cooling or during the second heating cycle irrespective of the composition. Infrared spectroscopy and molecular modeling indicated that KET and LAs formed DEMs, but in the KET-PRO systems small quantities of carboxylate anions were present.
Endocytosis: The Nanoparticle and Submicron Nanocompounds Gateway into the Cell
Authors: Manzanares Darío , Ceña Valentín
Published: April 2020

Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering therapeutic compounds to cells. Their entry into the cell represents the initial step in this delivery process, being most of the nanoparticles taken up by endocytosis, although other mechanisms can contribute to the uptake. To increase the delivery efficiency of therapeutic compounds by NPs and submicron particles is very relevant to understand the mechanisms involved in the uptake process. This review covers the proposed pathways involved in the cellular uptake of different NPs and submicron particles types as well as the role that some of the physicochemical nanoparticle characteristics play in the uptake pathway preferentially used by the nanoparticles to gain access and deliver their cargo inside the cell.
Real Life Population Pharmacokinetics Modelling of Eight Factors VIII in Patients with Severe Haemophilia A: Is It Always Relevant to Switch to an Extended Half-Life?
Authors: Allard Quentin , Djerada Zoubir , Pouplard Claire , Repessé Yohann , Desprez Dominique , Galinat Hubert , Frotscher Birgit , Berger Claire , Harroche Annie , Ryman Anne , Flaujac Claire , Chamouni Pierre , Guillet Benoît , Volot Fabienne , Szymezak Jean , Nguyen Philippe , Cazaubon Yoann
Published: April 2020

We retrospectively analysed the data files of 171 adults and 87 children/adolescents with severe haemophilia, except for 14 patients (moderate; minor) (1), to develop a global population pharmacokinetic (PK) model for eight factors VIII (FVIII) that could estimate individual PK parameters for targeting the desired level of FVIII activity (FVIII:C); and (2) to compare half-life (HL) in patients switching from a standard half-life (SHL) to an extended half-life (EHL) and evaluate the relevance of the switch. One-stage clotting assay for the measurement of FVIII activity (FVIII:C, IU/mL) was used for population PK modelling. The software, Monolix version 2019R1, was used for non-linear mixed-effects modelling. A linear two-compartment model best described FVIII:C. The estimated PK parameters (between-subject variability) were: 2640 mL (23.2%) for volume of central compartment (V1), 339 mL (46.8%) for volume of peripheral compartment (V2), 135 mL/h for Q (fixed random effect), and 204 mL/h (34.9%) for clearance (Cl). Weight, age, and categorical covariate EHL were found to influence Cl and only weight for V1. This model can be used for all of the FVIII cited in the study. Moreover, we demonstrated, in accordance with previous studies, that Elocta had longer half-life (EHL) than SHL (mean ratio: 1.48) as compared to Advate, Factane, Kogenate, Novoeight, and Refacto.
Polyphenols-Loaded Sericin Self-Assembling Nanoparticles: A Slow-Release for Regeneration by Tissue-Resident Mesenchymal Stem/Stromal Cells
Authors: Orlandi Giulia , Bari Elia , Catenacci Laura , Sorrenti Milena , Segale Lorena , Faragò Silvio , Sorlini Marzio , Arciola Carla Renata , Torre Maria Luisa , Perteghella Sara
Published: April 2020

Mesenchymal stem/stromal cells (MSCs) are a therapeutic target to promote tissue regeneration, mainly when oxidative stress-mediated damage is involved in disease pathogenesis. Here, slow-release silk sericin nanoparticles (SNPs) loaded with natural antioxidant polyphenols were developed to sustain regeneration by tissue-resident MSCs. SNPs were prepared by exploiting a self-assembly method with poloxamer and were loaded with proanthocyanidins (P), quercetin (Q) or epigallocatechin gallate (E). SNPs, with a diameter less than 150 nm, were able to encapsulate both hydrophilic (P and E) and hydrophobic (Q) drugs. A slow and controlled release was obtained from SNPs for all the actives in PBS, while in EtOH, Q and E showed a burst release but P did not. Kinetic models revealed lower diffusion of P than other biomolecules, probably due to the higher steric hindrance of P. The in vitro anti-oxidant, anti-elastase and anti-tyrosinase properties of SNPs were assessed: loading the P and E into SNPs preserved the in vitro biological activities whereas for Q, the anti-elastase activity was strongly improved. Moreover, all formulations promoted MSC metabolic activity over 72 h. Finally, SNPs exhibited a strong ability to protect MSCs from oxidative stress, which supports their potential use for regenerative purposes mediated by tissue-resident MSCs.
Evaluation of Medication Error Incident Reports at a Tertiary Care Hospital
Authors: Aseeri Mohammed , Banasser Ghadeer , Baduhduh Omar , Baksh Sabirin , Ghalibi Nasser
Published: April 2020

Background: Medications errors (MEs) have been a major concern of healthcare systems worldwide. Voluntary-based incident reporting is the mainstay system to detect such events in many institutions. However, the number of reports can be highly variable across institutions depending on their adoption of the safety culture. This study aimed to evaluate and analyze medication error incidents that were submitted through the hospital safety reporting system in 2015 at a tertiary care center in the western region of Saudi Arabia, and to explore the most common types of harmful MEs in addition to the risk factors that led to such harmful incidents. Methods: This is a descriptive study that was conducted utilizing 624 medication error reports extracted from the hospital safety reporting system. Reports were analyzed based on the medication name, event type, event description, nodes of the medication use process, harm score (adapted from the National Coordinating Council for Medication Error Reporting and Prevention harm index), patients’ age/gender, incident setting, and time of occurrence as documented in the Safety Reporting System (SRS). Furthermore, all errors that resulted in injury or harm to patients had a deeper review by two senior pharmacists to find contributing factors that led to these harmful incidents and recommend system-based preventive strategies. Results: This study showed that most reported incidents were near misses (69.3%). The pediatric population was involved in 28.4% of the incident reports. Most of the reported incidents were categorized as occurring in the inpatient setting (57.4%). Medication error incidents were more likely to be reported in the morning shift versus evening and night shift (77.4% vs. 22.6%). Most reported incidents involved the dispensing stage (36.7%). High-alert medications were reported in 281 out of 624 events (45%). Conclusions: The hospital medication safety reporting program is a great tool to identify system-based issues in the medication management system. This study identified many opportunities for improvement in the medication use system, especially in management of chemotherapy and anticoagulant agents.
A Novel Approach to Atomistic Molecular Dynamics Simulation of Phenolic Resins Using Symthons
Authors: Bone Matthew A. , Macquart Terence , Hamerton Ian , Howlin Brendan J.
Published: April 2020

Materials science is beginning to adopt computational simulation to eliminate laboratory trial and error campaigns—much like the pharmaceutical industry of 40 years ago. To further computational materials discovery, new methodology must be developed that enables rapid and accurate testing on accessible computational hardware. To this end, the authors utilise a novel methodology concept of intermediate molecules as a starting point, for which they propose the term ‘symthon’ (The term ‘Symthon’ is being used as a simulation equivalent of the synthon, popularised by Dr Stuart Warren in ‘Organic Synthesis: The Disconnection Approach’, OUP: Oxford, 1983.) rather than conventional monomers. The use of symthons eliminates the initial monomer bonding phase, reducing the number of iterations required in the simulation, thereby reducing the runtime. A novel approach to molecular dynamics, with an NVT (Canonical) ensemble and variable unit cell geometry, was used to generate structures with differing physical and thermal properties. Additional script methods were designed and tested, which enabled a high degree of cure in all sampled structures. This simulation has been trialled on large-scale atomistic models of phenolic resins, based on a range of stoichiometric ratios of formaldehyde and phenol. Density and glass transition temperature values were produced, and found to be in good agreement with empirical data and other simulated values in the literature. The runtime of the simulation was a key consideration in script design; cured models can be produced in under 24 h on modest hardware. The use of symthons has been shown as a viable methodology to reduce simulation runtime whilst generating accurate models.
Influence of Coupling Agent in Mechanical, Physical and Thermal Properties of Polypropylene/Bamboo Fiber Composites: Under Natural Outdoor Aging
Authors: Fajardo Cabrera de Lima Lety del Pilar , Santana Ruth Marlene Campomanes , Chamorro Rodríguez Cristian David
Published: April 2020

Researches on thermoplastic composites using natural fiber as reinforcement are increasing, but studies of durability over time are scarce. In this sense the objective of this study is to evaluate changes in the properties of polypropylene/bamboo fiber (PP/BF) composite and the influence of the use of coupling agent (CA) in these composites after natural ageing. The PP/BF (70/30 wt) composites and 3% wt CA (citric acid from natural origin and maleic anhydride grafted polypropylene from petrochemical origin) were prepared by using an internal mixer chamber and then injection-molded. The samples were exposed to natural weathering for a total period of 12 months and characterized before and after exposure. All exposed composites experienced a decrease in their properties, however, the use of CA promoted more stability; in mechanical properties, the composites with CA showed lower loss about 23% in Young′s modulus, 18% in tensile stress at break, and 6% in impact strength. This behavior was similar in thermal and physical properties, the result for the CA of natural origin being similar to that of synthetic origin. These results indicate that the use of a CA may promote higher interaction between the fiber and the polymer. In addition, the CAs of organic origin and synthetic origin exhibited similar responses to natural ageing.
Effect of Reversible Addition-Fragmentation Transfer Emulsion Styrene Butadiene Rubber (RAFT ESBR) on the Properties of Carbon Black-Filled Compounds
Authors: Hwang Kiwon , Mun Hyunsung , Kim Wonho
Published: April 2020

Tread is an important component that directly affects the performance of passenger car radial (PCR) tires. Styrene-butadiene rubber (SBR) is mainly used for tire tread and it includes solution styrene-butadiene rubber (SSBR) and emulsion styrene-butadiene rubber (ESBR). Although SSBR is mainly used, the manufacturing process for SSBR is more challenging than ESBR, which is environmentally friendly, but has the disadvantage of a broad molecular weight distribution. To overcome this, a reversible addition-fragmentation radical transfer (RAFT) polymerization technique is used in ESBR polymerization. An environmentally friendly RAFT ESBR with a narrow dispersity can be polymerized. Here, carbon black-filled compounds were manufactured while using RAFT ESBR, and their properties were compared to ESBR. The analysis showed a low crosslink density of RAFT ESBR, due to the high polysulfide crosslink structure. We manufactured a carbon black-filled compound with the same crosslink density and structure as the ESBR carbon black-filled compound, and the effect of the dispersity of the base polymer was investigated. RAFT ESBR showed 9% better abrasion resistance and 29% better fuel efficiency than ESBR, according to the analysis of the data. The narrow dispersity can reduce energy loss and positively influence the abrasion resistance and fuel efficiency.
Melamine Foams Decorated with In-Situ Synthesized Gold and Palladium Nanoparticles
Authors: Pinto Javier , Barroso-Solares Suset , Magrì Davide , Palazon Francisco , Lauciello Simone , Athanassiou Athanassia , Fragouli Despina
Published: April 2020

A versatile and straightforward route to produce polymer foams with functional surface through their decoration with gold and palladium nanoparticles is proposed. Melamine foams, used as polymeric porous substrates, are first covered with a uniform coating of polydimethylsiloxane, thin enough to assure the preservation of their original porous structure. The polydimethylsiloxane layer allows the facile in-situ formation of metallic Au and Pd nanoparticles with sizes of tens of nanometers directly on the surface of the struts of the foam by the direct immersion of the foams into gold or palladium precursor solutions. The effect of the gold and palladium precursor concentration, as well as the reaction time with the foams, to the amount and sizes of the nanoparticles synthesized on the foams, was studied and the ideal conditions for an optimized functionalization were defined. Gold and palladium contents of about 1 wt.% were achieved, while the nanoparticles were proven to be stably adhered to the foam, avoiding potential risks related to their accidental release.
Recent Advances in Tissue Adhesives for Clinical Medicine
Authors: Ge Liangpeng , Chen Shixuan
Published: April 2020

Tissue adhesives have attracted more attention to the applications of non-invasive wound closure. The purpose of this review article is to summarize the recent progress of developing tissue adhesives, which may inspire researchers to develop more outstanding tissue adhesives. It begins with a brief introduction to the emerging potential use of tissue adhesives in the clinic. Next, several critical mechanisms for adhesion are discussed, including van der Waals forces, capillary forces, hydrogen bonding, static electric forces, and chemical bonds. This article further details the measurement methods of adhesion and highlights the different types of adhesive, including natural or biological, synthetic and semisynthetic, and biomimetic adhesives. Finally, this review article concludes with remarks on the challenges and future directions for design, fabrication, and application of tissue adhesives in the clinic. This review article has promising potential to provide novel creative design principles for the generation of future tissue adhesives.
Development of an Analytical Model to Describe the Disperse Melting in Wave-Dispersion Screws
Authors: Dörner Marius , Marschik Christian , Schöppner Volker , Steinbichler Georg
Published: April 2020

The progressive development of new screw concepts in single screw extrusion also makes it necessary to develop new models for the correct process description. When looking at wave-dispersion screws, the disperse melting behavior should be mentioned in particular, which has so far been less researched and modeled than the conventional melting behavior, as it occurs in standard screws. Therefore, an analytical model is presented in this paper, which considers the disperse melting under consideration of the melt and solid temperature. The basic assumption is Fourier heat conduction from the melt surrounding the particles into the particles. Furthermore, the melt temperature development by dissipation and the cooling effects were modeled analytically. Additionally, the solid bed temperature was modeled by a 2D-FDM method. By dividing the screw into several calculation sections with constant boundary conditions, it was subsequently possible to calculate the melting process over the screw length. The model developed shows comprehensible results in verification and successfully reproduces the solids content over the screw length with a mean deviation of absolute 11% in validation tests using cooling/pulling-out experiments.
Acrylate-Based Hybrid Sol-Gel Coating for Corrosion Protection of AA7075-T6 in Aircraft Applications: The Effect of Copolymerization Time
Authors: Rodič Peter , Korošec Romana Cerc , Kapun Barbara , Mertelj Alenka , Milošev Ingrid
Published: April 2020

Pre-hydrolysed/condensed tetraethyl orthosilicate (TEOS) was added to a solution of methyl methacrylate (MMA) and 3-methacryloxypropyltrimethoxysilane (MAPTMS), and then copolymerised for various times to study the influence of the latter on the structure of hybrid sol-gel coatings as corrosion protection of aluminium alloy 7075-T6. The reactions taking place during preparation were characterised using real-time Fourier transform infrared spectroscopy, dynamic light scattering and gel permeation chromatography. The solution characteristics were evaluated, using viscosimetry, followed by measurements of thermal stability determined by thermogravimetric analysis. The optimal temperature for the condensation reaction was determined with the help of high-pressure differential scanning calorimetry. Once deposited on 7075-T6 substrates, the coatings were evaluated using a field emission scanning electron microscope coupled to an energy dispersive spectrometer to determine surface morphology, topography, composition and coating thickness. Corrosion properties were tested in dilute Harrison’s solution (3.5 g/L (NH4)2SO4 and 0.5 g/L NaCl) using electrochemical impedance spectroscopy. The copolymerization of MMA and MAPTMS over 4 h was optimal for obtaining 1.4 µm thick coating with superior barrier protection against corrosion attack (|Z10 mHz| ~ 1 GΩ cm2) during three months of exposure to the corrosive medium.
Silane Effect of Universal Adhesive on the Composite–Composite Repair Bond Strength after Different Surface Pretreatments
Authors: Michelotti Gioia , Niedzwiecki Maria , Bidjan Darius , Dieckmann Phoebe , Deari Shengjile , Attin Thomas , Tauböck Tobias T.
Published: April 2020

This study investigated the impact of a separate silanization step on the repair bond strength of composite substrates using a universal adhesive after various mechanical surface treatments. Composite specimens were aged and exposed to the following mechanical roughening treatments: diamond bur abrasion, aluminum oxide sandblasting, or silica coating. The specimens were then either left untreated or conditioned with universal adhesive (Scotchbond Universal), or a silane coupling agent was applied before the use of the universal adhesive or a conventional adhesive (Optibond FL). The conditioned surfaces and fresh substrate (positive control group) were covered with repair composite, and microtensile bond strength testing was performed. The significantly highest bond strength was obtained in the positive control group. Repair bond strength of the universal adhesive applied after a separate silanization step was similar to that without prior silanization, independent of the mechanical surface treatment. Moreover, after silica coating, no significant differences in the repair bond strength were detected among the different adhesive treatments. In conclusion, a separate silanization step before surface conditioning with the universal adhesive does not enhance the repair bond strength. On silica-coated composite substrates, repair bond strength values of the universal adhesive were similar to those of the conventional adhesive.
Drag Reduction Performance and Mechanism of Hydrophobic Polymers in Fresh Water and Brine
Authors: Tan Hongzhong , Mao Jincheng , Zhang Wenlong , Yang Bo , Yang Xiaojiang , Zhang Yang , Lin Chong , Feng Jianfa , Zhang Hao
Published: April 2020

Three kinds of drag reducer were synthesized by inverse emulsion polymerization and named PHWAM-1, PHWAM-2, and PHWAM-3. Drag reduction (DR) tests showed that the three drag reducers have different DR characteristics in fresh water and various saline waters because of their different types of hydrophobic monomers. PHWAM-1, without hydrophobic monomers, performs better in fresh water, while PHWAM-2 and PHWAM-3, with hydrophobic monomers, perform better in brine. In addition, PHWAM-3, which has twin-tailed hydrophobic monomers, performs best in high-concentration brine. Measurements of micro-particle size and observations of spatial structure suggest that although the stronger hydrophobic polymer has no DR advantage over a linear polymer in fresh water, the molecular chains form a mutually associative supporting structure that improves the DR performance over that of a linear polymer in high-concentration brine.
Synthesis and Aggregation Behavior of Temperature- and pH-Responsive Glycopolymers as Sugar-Displaying Conjugates
Authors: Tsuji Sotaro , Aoki Tomohiro , Ushio Shunsuke , Tanaka Tomonari
Published: April 2020

Stimuli-responsive polymers have attracted significant interest in the fields of advanced materials and biomaterials. Herein, temperature- and pH-responsive glycopolymers, which are composed of N-isopropylacrylamide, methacrylic acid, and an acrylamide derivative bearing a lactose moiety, were synthesized via radical copolymerization. The series of resulting glycopolymers had different degrees of substitution of the lactose moieties, were responsive to temperatures between 26.6 °C and 47.6 °C, and formed aggregates above the lower critical solution temperature limit in mild acidic aqueous media (pH 4–6). The temperature-responsive behavior was dependent on the prevailing pH conditions, as no aggregation was observed in neutral and basic aqueous media (pH > 7). The aggregates had saccharide moieties on the surface in aqueous media. The number of saccharide moieties on the surface depended on the saccharide-containing unit ratio in the glycopolymer. The ratio was determined via enzymatic hydrolysis of the lactose moieties using β-galactosidase and the subsequent detection of the released galactose.
Cellulose Nanocrystals Derived from Textile Waste through Acid Hydrolysis and Oxidation as Reinforcing Agent of Soy Protein Film
Authors: Huang Shuting , Tao Ran , Ismail Ashraf , Wang Yixiang
Published: April 2020

More than 10 million tons of textile waste are disposed through landfill every year in North America. The disposal of textile waste via landfill or incineration causes environmental problems and represents a waste of useful resources. In this work, we explored the possibility to directly extract cellulose nanocrystals (CNCs) from untreated textile waste through two methods, namely sulfuric acid hydrolysis and three-step oxidization. CNCs with cellulose Iβ crystalline structure and rod-like shape were successfully obtained. The aspect ratios of CNCs prepared from acid hydrolysis and oxidization were 10.00 ± 3.39 and 17.10 ± 12.85, respectively. Their application as reinforcing agent of soybean protein isolate (SPI) film was evaluated. With the addition of 20% CNCs, the composite film maintained the high transparency, while their water vapor barrier property, tensile strength, and Young’s modulus were significantly improved. This research demonstrates a promising approach to recycle textile waste, and more value-added applications based on the derived CNCs could be expected.
Oxidation and Characterization of Low-Concentration Gas in a High-Temperature Reactor
Authors: Chen Jinhua , Wen Guangcai , Yan Song , Lan Xiangyun , Xiao Lu
Published: April 2020

To achieve the efficient utilization of low-concentration mine gas, reduce resource waste and alleviate environmental pollution, the high-temperature oxidation of low-concentration gas at a concentration range of 1.00% to 1.50%, which is directly discharged into the atmosphere during coal mine production, was carried out to recover heat for reuse. The gas oxidation equipment was improved for the heating process and the safety of low-concentration gas oxidation under a high-temperature environment was evaluated. The experimental results showed that the reactor could provide a 1000 °C high-temperature oxidation environment for gas oxidation after installing high-temperature resistant ceramics. The pressure variation curves of the reactor with air and different concentrations of gas were similar. Due to the thermal expansion, the air pressure slightly increased and then returned to normal pressure. In contrast, the low-concentration gas exhibited a stable pressure response in the high-temperature environment of 1000 °C. The outlet pressure was significantly greater than the inlet pressure, and the pressure difference between the inlet and outlet exhibited a trend to increase with the gas concentration. The minimum pressure difference was 4 kPa (air) and the maximum was 11 kPa (1.50% gas). The explosion limit varied with the temperature and the blend of oxidation products. The ratio of measured gas pressure to air pressure after oxidation was below the explosion criterion, indicating that the measured concentration of gas is still safe after the shift of the explosion limit, which provides a safe concentration range for the efficient use of low-concentration gas in the future.
Gendering Dance
Authors: Gera Roy Anjali
Published: April 2020

Originating as a Punjabi male dance, bhangra, reinvented as a genre of music in the 1980s, reiterated religious, gender, and caste hierarchies at the discursive as well as the performative level. Although the strong feminine presence of trailblazing female DJs like Rani Kaur alias Radical Sista in bhangra parties in the 1990s challenged the gender division in Punjabi cultural production, it was the appearance of Taran Kaur Dhillon alias Hard Kaur on the bhangra rap scene nearly a decade and a half later that constituted the first serious questioning of male monopolist control over the production of Punjabi music. Although a number of talented female Punjabi musicians have made a mark on the bhangra and popular music sphere in the last decade or so, Punjabi sonic production continues to be dominated by male, Jat, Sikh singers and music producers. This paper will examine female bhangra producers’ invasion of the hegemonic male, Sikh, Jat space of bhangra music to argue that these female musicians interrogate bhangra’s generic sexism as well as the gendered segregation of Punjabi dance to appropriate dance as a means of female empowerment by focusing on the music videos of bhangra rapper Hard Kaur.
An Introduction to the Geostationary-NASA Earth Exchange (GeoNEX) Products: 1. Top-of-Atmosphere Reflectance and Brightness Temperature
Authors: Wang Weile , Li Shuang , Hashimoto Hirofumi , Takenaka Hideaki , Higuchi Atsushi , Kalluri Satya , Nemani Ramakrishna
Published: April 2020

GeoNEX is a collaborative project led by scientists from NASA, NOAA, and many other institutes around the world to generate Earth monitoring products using data streams from the latest Geostationary (GEO) sensors including the GOES-16/17 Advanced Baseline Imager (ABI), the Himawari-8/9 Advanced Himawari Imager (AHI), and more. An accurate and consistent product of the Top-Of-Atmosphere (TOA) reflectance and brightness temperature is the starting point in the scientific processing pipeline and has significant influences on the downstream products. This paper describes the main steps and the algorithms in generating the GeoNEX TOA products, starting from the conversion of digital numbers to physical quantities with the latest radiometric calibration information. We implement algorithms to detect and remove residual georegistration uncertainties automatically in both GOES and Himawari L1bdata, adjust the data for topographic relief, estimate the pixelwise data-acquisition time, and accurately calculate the solar illumination angles for each pixel in the domain at every time step. Finally, we reproject the TOA products to a globally tiled common grid in geographic coordinates in order to facilitate intercomparisons and/or synergies between the GeoNEX products and existing Earth observation datasets from polar-orbiting satellites.
The Trend Inconsistency between Land Surface Temperature and Near Surface Air Temperature in Assessing Urban Heat Island Effects
Authors: Sun Tao , Sun Ranhao , Chen Liding
Published: April 2020

The credible urban heat island (UHI) trend is crucial for assessing the effects of urbanization on climate. Land surface temperature (LST) and near surface air temperature (SAT) have been extensively used to obtain UHI intensities. However, the consistency of UHI trend between LST and SAT has rarely been discussed. This paper quantified the temporal stability and trend consistency between Moderate Resolution Imaging Spectroradiometer (MODIS) LST and in situ SAT. Linear regressions, temporal trends and coefficients of variations (CV) were analyzed based on the yearly mean, maximum and minimum temperatures. The findings in this study were: (1) Good statistical consistency (R2 = 0.794) and the same trends were found only in mean temperature between LST-UHI and SAT-UHI. There are 54% of cities that showed opposite temporal trends between LST-UHI and SAT-UHI for minimum temperature while the percentage was 38% for maximum temperature. (2) The high discrepancies in temporal trends were observed for all cities, which indicated the inadequacy of LST for obtaining reliable UHI trends especially when using the maximum and minimum temperatures. (3) The larger uncertainties of LST-UHI were probably due to high inter-annual fluctuations of LST. The topography was the predominant factor that affected the UHI variations for both LST and SAT. Therefore, we suggested that SAT should be combined with LST to ensure the dependable temporal series of UHI. This paper provided references for understanding the UHI effects on various surfaces.
Improved Bluetooth Low Energy Sensor Detection for Indoor Localization Services
Authors: Pušnik Maja , Galun Mitja , Šumak Boštjan
Published: April 2020

Advancements in protocols, computing paradigms, and electronics have enabled the development of wireless sensor networks (WSNs) with high potential for various location-based applications in different fields. One of the most important topics in WSNs is the localization in environments with sensor nodes being scattered randomly over a region. Localization techniques are often challenged by localization latency, efficient energy consumption, accuracy, environmental factors, and others. The objective of this study was to improve the technique for detecting the nearest Bluetooth Low Energy sensor, which would enable the development of more efficient mobile applications for location advertising at fairs, exhibitions, and museums. The technique proposed in this study was based on the iBeacon protocol, and it was tested in a controlled room with three environmental settings regarding the density of obstacles, as well as in a real-world setting at the Expo Museum at Postojna in Slovenia. The results of several independent measures, conducted in the controlled room and in the real-world environment, showed that the proposed algorithm outperformed the standard algorithm, especially in the environments with a medium or high densities of obstacles. The results of this study can be used for the more effective planning of placing beacons in space and for optimizing the algorithms for detecting transmitters in mobile location-based applications that provide users with contextual information based on their current location.
Effects of Cultivated Area on Smallholder Farm Profits and Food Security in Rural Communities of the Eastern Cape Province of South Africa
Authors: Mujuru Nyarai M. , Obi Ajuruchukwu
Published: April 2020

As rural poverty deepens over much of Sub-Saharan Africa, smallholder transformation has become more urgent than ever before. A majority of rural people derive their livelihoods from agriculture, hence the urgent need for transforming the sector. The South African government launched a comprehensive land reform programme at the dawn of democracy in the country on the assumption that constraints on land size would be eliminated to make room for a more inclusive agricultural economy. The present study sought to assess how cultivated area affects food security and the profits of maize and cabbage farmers. The purposive sampling technique was used for the selection of study sites, from which 158 irrigators and homestead gardeners were selected. The data were then subjected to analysis by defining a maximum likelihood estimator that combines the seemingly unrelated regression (SUR) and one-way error correction model, to determine the factors influencing food security and farm profits. The model revealed diverse relationships, suggesting that location, farm type and income were important variables in explaining food security. The area under cultivation was found to influence profits for both crops. Policies in favour of technology adoption, market access and input use would greatly incentivize farmers to cultivate larger plots of land.
Research on the Regional Differences and Influencing Factors of the Innovation Efficiency of China’s High-Tech Industries: Based on a Shared Inputs Two-Stage Network DEA
Authors: Chen Huangxin , Lin Hang , Zou Wenjie
Published: April 2020

Innovation ability has become one of the core elements in the pursuit of China’s green growth, and high-tech industries are playing a leading role in technological innovation in China. With the rapid development of China’s high-tech industries, their innovation efficiency has attracted widespread attention. This article aims to illustrate a shared inputs two-stage network Data Envelopment Analysis (DEA), to measure the innovation efficiency of high-tech industries in China’s 29 provinces from 1999 to 2018. The results indicate that there are obvious differences in the innovation efficiency of the provinces. The technology development efficiency, the technical transformation efficiency, and the overall innovation efficiency of the developed east coast provinces are generally higher than those of the backward central and western provinces. This article further applies the spatial econometrics model to analyze the factors influencing the innovation efficiency of high-tech industries. We have found that government support, R&D input intensity, industries aggregation, economic extroversion, and the level of development of the modern service industries cause varying degrees of impact on innovation efficiency.
Effect of Indigenous Microbial Consortium on Bioleaching of Arsenic from Contaminated Soil by Shewanella putrefaciens
Authors: Tran Thi Minh , Han Hyeop-Jo , Ko Ju-In , Lee Jong-Un
Published: April 2020

The effects of indigenous microbial consortium on removal of As from As-contaminated soil using an Fe(III)-reducing bacterium Shewanella putrefaciens were investigated under circumneutral pH condition. Sequential extraction of As revealed that more than 30% of As was associated with Fe(III)-(oxy)hydroxides in the soil. Bioleaching experiments were conducted anaerobically with a supply of lactate as a carbon source. The highest As removal efficiency (57.5%) was obtained when S. putrefaciens and indigenous bacterial consortium coexisted in the soil. S. putrefaciens and indigenous bacteria solely removed 30.1% and 16.4% of As from the soil, respectively. The combination of S. putrefaciens and indigenous bacteria led to a higher amount of labile As after microbial dissolution of Fe(III)-(oxy)hydroxides. After microbial treatment, soil quality represented by pH and organic content appeared to be preserved. The results indicated that the ecological and physiological understanding of the indigenous microbiome might be important for the efficient application of bioleaching technology to remove As from contaminated soils.
Carbon and Water Footprints of Tibet: Spatial Pattern and Trend Analysis
Authors: Xie Wu , Hu Shuai , Li Fangyi , Cao Xin , Tang Zhipeng
Published: April 2020

Tibet in China has extremely a fragile natural ecosystem, which is under a great pressure from global changes. The carbon footprint (CF) and water footprint (WF), reflecting the pressures of regional development on the natural environment, represent a lacuna in the field of study in Tibet due to missing data. In this paper, the 2012 multi-regional input–output table of China was employed to quantify the CF and WF of Tibet and the relationship between Tibet and other provinces of China. Spatial pattern and key sectors were also studied to demonstrate the current characters and the future trend of footprints. Tibet’s carbon emission was 4.0 Mt, 32.7% of CF, indicating that Tibet was a net importing region of carbon emission. Tibet received embodied carbon emission by trade from other regions, especially from Hebei, Inner Mongolia and Henan provinces, but played a complex role in virtual water allocation by transferring to most provinces and receiving from some provinces. The CF of Tibet will increase under different scenarios of 2030, but the WF can be restricted to 2.5 Gt in the slow scenario. In the future, imports of virtual resources will benefit the fragile ecosystem of Tibet and moreover, it is vital to restrict the local resource-intensive sectors and improve resource-use efficiency.
Joint Ventures between Online Portals and News Publishers: Will they be an Alternative to Symbiosis?
Authors: Ryu Min Ho , Park Jieun , Kwak Kyu Tae
Published: April 2020

Around the world, legacy news publishers are suffering from the deep decline of revenues and face the challenge of survival. As the situation continues, conflicts between online portal and news producers are also intensifying. Under these circumstances, Naver, the biggest internet portal in Korea, and several Korean news publishers have begun to seek a new breakthrough—media joint ventures. The joint venture between online portals and news publishers is a unique collaboration model that has not been found in other countries. This study investigates the motivation of the media joint ventures and evaluates the performance. To do this, the study suggests the sustainability of media joint ventures. This model consists of five major categories of media joint ventures’ performances, based on their strategic, financial, learning, managerial, and social influence aspects. After conducting an in-depth interview of media joint ventures and a focus group interview with nine experts from the media industry and business scholarships, the study shows that the media joint ventures could be a new alternative for both portals and news publishers. However, there were some differences in the sustainability evaluation of the operating body of the joint venture and outside experts.
Accounting for the Life Cycle Cost of Power Grid Projects by Employing a System Dynamics Technique: A Power Reform Perspective
Authors: Wang Yongli , Song Shanshan , Gao Mingchen , Wang Jingyan , Zhu Jinrong , Tan Zhongfu
Published: April 2020

In the context of China’s electric power reform, issued in May 2019, the “Transmission and Distribution Pricing Supervision Measures” have changed asset accounting in grid enterprises and therefore affected cost accounting in grid projects. This paper proposes a dynamic cost calculation model based on system dynamics and takes a power grid company as an example. On this basis, a sensitivity analysis of power grid engineering was conducted to determine the impacts of key factors of power reform on life cycle cost (LCC). Finally, suggestions for cost accounting and cost management were proposed.
What Is the Threshold Carbonization Temperature for Sustainable Preservation of the Good Nitrogen Supply Ability of Chicken Manure?
Authors: Daramy Moses Ahmed , Kawada Ryoka , Oba Shinya
Published: April 2020

Chicken manure (CM) carbonization is an efficient waste control method that converts manure into an agriculturally useful amendment. However, the recommended temperature range of 300–500 °C has led to confounding results on the maintenance of the nitrogen (N) supply ability of CM after carbonization, and thus requires further investigation. The objective of this study was to identify an upper limit (threshold) temperature to guide the carbonization of CM in order to ensure that the good N supply ability of the manure after carbonization is preserved. CM was carbonized at 350, 375, 400, 425, 450, and 475 °C. Afterwards, chemical properties, surface functional groups, N speciation, N supply ability, and their relationships were investigated. The results indicated that the N supply ability of CM carbonized at 350–375 °C was comparable to the N supply ability of CM, which is possibly due to the minute alteration of the chemical properties, surface functionality, and N speciation that occurred in CM at these temperatures. At ≥400 °C, the N supply ability of CM was significantly reduced due to the increasing alterations of the chemical makeup as heating temperature increased. For sustainable maintenance of the good N supply ability of CM after carbonization, the manure should not be carbonized above 375 °C.
An Environmental Justice Assessment of the Waste Treatment Facilities in Shanghai: Incorporating Counterfactual Decomposition into the Hedonic Price Model
Authors: Zou Can , Tai Jun , Chen Li , Che Yue
Published: April 2020

Environmental justice (EJ) has become an increasingly significant issue for environmental management and has thus attracted increasing government and public attention. Although some studies have used techniques of proximity based on geographical information systems to assess EJ, their research is limited to individual or household data. Unlike the conventional hedonic price model (HPM) examining the effects of environmental features on housing rent, this article incorporates counterfactual decomposition into the HPM to estimate the environmental pressure on different groups by comparing the externality effects of municipal solid waste treatment facilities (MSWTFs) on two separate groups of people. To explore whether and, if so, the extent to which, vulnerable groups of people are restricted to disproportionate impacts of hazardous environmental facilities, this research uses Shanghai as the study area to highlight specific locations and exemplify the environmental injustice between the rich and the poor. The results, which represent the relationship between environmental quality and property prices, indicate that environmental quality is a robust predictor of housing rent. Simultaneously, the results suggest that some people conform better to environmental pressure than do others. Thus, the environmental impact of MSWTFs on different populations should be considered, and compensation policies should be implemented for disadvantaged groups.