bluuebunny/crossref_metadata_2025 huggingface dataset:
Antioxidant and Enzyme Inhibitory Activities of Areca catechu, Boesenbergia rotunda, Piper betle and Orthosiphon aristatus for Potential Skin Anti-aging Properties
Authors: Mat Yasin Z.A. , Khazali A.S. , Ibrahim F. , Nor Rashid N. , Yusof R.
Published: January 2020

Medicinal plants have been traditionally used for various applications including skin care. In this study, Areca catechu, Boesenbergia rotunda, Piper betle and Orthosiphon aristatus were tested for antioxidant and anti-aging properties. These plant extracts were subjected to 1,1-diphenyl-picrylhydrazyl (DPPH) and 2,2ʹ-azinobis(3-ethylbenzothiazoline)-6-sulphonic acid (ABTS) radical scavenging activity analyses. The extracts were then assessed for collagenase, elastase and hyaluronidase inhibition and subjected to toxicity study in normal human dermal fibroblast cells. Lastly, bioactive compounds in these plant extracts were identified using high performance liquid chromatography. We found that Piper betle and Areca catechu possessed high total flavonoid and phenolic contents. These two extracts showed the best IC50 values for DPPH and ABTS radical scavenging activities and also demonstrated the highest elastase and collagenase inhibition when compared to the other two plant extracts. These crude plants extracts were also non-toxic to normal human dermal fibroblast cells. Our HPLC results identified several potential bioactive compounds in these plant extracts that could be crucial in mediating the observed effects. Based on our results, these plant extracts especially Piper betle and Areca catechu extracts possess significant antioxidant and anti-aging properties and could be utilized in the development of safe and cost-effective anti-aging treatments.
Anthelmintic Effect of Date Palm Fruit: A Systematic Review
Authors: Rauf A. , Addnan F.H. , Manzor N.F.M. , Abdullah W.O. , Elkadi M.A. , Hamdan F. , Aripin K.N.N. , Behnke J.M. , Mansur F.A.F.
Published: January 2020

Soil-transmitted helminth infections constitute a global affliction affecting people and livestock, resulting in a significant disease burden and economic losses in endemic regions. However, control has not been entirely successful and the problem is compounded by the development of resistance to available chemotherapy. Novel alternative compounds are urgently needed, encouraging the screening of largely plant-based sources for anthelmintic effects. Date palm fruit (Phoenix dactylifera) is a popular and nutritious food much coveted for its nutraceutical effect. There are convincing reports documenting the antibacterial, antiviral and antifungal effects of date palm fruit but evidence for any potential anthelmintic effect remains unclear. Here we conducted a systematic review of the published information through an electronic search using six scientific databases; SCOPUS, MEDLINE COMPLETE, OVID, EMBASE, WEB OF SCIENCE and CINAHL COMPLETE. Out of 58 studies that were initially identified only 2 manuscripts fitted our inclusion criteria. The first article reported on the anthelmintic effect of date palm fruit against the rodent nematodes Trichuris muris and Angiostrongylus cantonensis in vitro and in vivo while the second article was based only on in vivo assessment (with coconut) of the effect on the rodent cestode Hymenolepis microstoma. Our review revealed limited anecdotal reports of the anthelmintic effect of date palm fruit against parasitic helminths, however, the majority of reports were inconclusive due to mixed results, limited focus on date palm fruit and lack of any statistical analyses. Rigorous, systematic and fully controlled studies focusing on date palm fruit are needed to validate the anecdotal evidence.
Structural and Functional Characteristics of Chinese Dioscorea Esculenta and Dioscorea Opposita Starches
Authors: Wen-Jia Shi , Li-Ming Zhang , Li-Min Hao , Qiao-Ling Peng , Yu-Jie Dai
Published: January 2020

Physicochemical, structural, and functional characteristics of starch from Dioscorea esculenta was compared with that from Dioscorea opposita Thunb. The scanning electron microscopy results showed that starches from D. esculenta and D. opposita differed in morphological features and distribution of granule size. While the D. esculenta starch possessed irregular, polygonal shape with the particle size distribution in the range of 1.7–4.2 μm, the D. opposita starch displayed large, oval and smooth shape with the particle size distribution in the range of 15.4–39.5 μm. The D. esculenta starch displayed a B-form diffraction pattern with 36.8% of crystalline degree, while the D. opposita starch exhibited a C-form crystalline pattern with 26.5% of crystalline degree. The amylose contents were also different for D. esculenta starch (18.15%) and D. opposita starch (22.43%). The gelatinization temperature (peak temperature) of D. esculenta starch (76.34°C) was lower than that of D. opposita starch (79.81°C). The pasting initial temperature (Ti), maximum viscosity, breakdown viscosity, and setback viscosity of D. esculenta starch were 68.7°C, 359 BU, 0 BU, and 262 BU, respectively. Interestingly, the amounts of readily digestible and slowly digestible starch contents in D. esculenta starch were higher, whereas its resistant starch contents were lower than those of D. opposita starch.
Physical Properties of Fe3+/TiO2 Nanoparticles and Photocatalytic Disinfection of Foodborne Microorganisms
Authors: Men Long , Ge Zhan , Meng-Yun Sun , Hong Zhuang , Ran Wang
Published: January 2020

In this article, we studied the preparation of Fe3+/TiO2 nanoparticles and the photocatalytic disinfection effects of two typical foodborne microorganisms, a gram-negative bacterium (Salmonella typhimurium) and a gram-positive bacterium (Listeria monocytogenes), in meat products. The physical properties of Fe3+/TiO2 nanoparticles embedded with various levels of Fe3+ (0%–10%) and synthesized through an impregnation process were investigated using X-ray diffraction, transmission electron microscopy, and UV-vis spectrophotometer, and their photocatalytic activities were evaluated by measuring the degradation of methylene blue dye and the disinfection of foodborne pathogens S. typhimurium and L. monocytogenes under visible light and UV light. Fe3+ ions were found to be scattered across TiO2 surfaces or across TiO2 crystal lattices as microcrystals. However, the capacity for TiO2 nanoparticles to absorb visible light was significantly enhanced after they were embedded with.Fe3+/TiO2 nanoparticles with molar ratios (R) of Fe3+ to TiO2 of 0.001:1, 0.005:1, and 0.01:1 exhibited higher levels of methylene blue dye photocatalytic degradation and higher levels of foodborne pathogen photocatalytic disinfection than the TiO2 control. However, nanoparticles containing >1% Fe3+ exhibited lower levels of photocatalytic activity than the TiO2 control. Salmonella typhimurium was more resistant to the nano-Fe3+/TiO2 treatment than L. monocytogenes under visible and UV light conditions. These experiments demonstrate that embedding Fe3+ in TiO2 nanoparticles does not remarkably influence the TiO2 nanoparticle size or structure. Embedding appropriate levels of Fe3+ content (0.1%–1%) can enhance the photocatalytic activity of TiO2 nanoparticles.
Irisin Ameliorates Hypoxia/Reoxygenation-Induced Inflammation and Apoptosis in PC12 Cells by Inhibiting TLR4/MYD88 Signaling Pathway
Authors: Jinli Wang , Fenfen Xu , Yuan Zheng , Xu Cheng , Piaopiao Zhang , Hongyang Zhao
Published: January 2020

Cardiovascular disease including cerebral ischemic stroke is the major complication that increases the morbidity and mortality in patients with diabetes mellitus as much as four times. It has been well established that irisin, with its ability to regulate glucose and lipid homeostasis as well as anti-inflammatory and anti-apoptotic properties, has been widely examined for its therapeutic potentials in managing metabolic disorders. However, the mechanism of irisin in the regulation of cerebral ischemic stroke remains unclear. Using PC12 cells as a model, we have shown that hypoxia/reoxygenation inhibits cell viability and increases lactic dehydrogenase. Irisin, in a dose-dependent manner, reversed these changes. The increase in inflammatory mediators (IL-1β, IL-6, and TNF-α) by hypoxia/reoxygenation was reversed by irisin. Furthermore, the cell apoptosis promoted by hypoxia/reoxygenation was also inhibited by irisin. Irisin suppressed TLR4/MyD88 signaling pathway leading to amelioration of inflammation and apoptosis in PC12 cells. Thus, inhibition of TLR4/MyD88 signaling pathway via irisin could be an important mechanism in the regulation of hypoxia/reoxygenation-induced inflammation and apoptosis in PC12 cells.
Enzyme-assisted Extraction for Optimized Recovery of Phenolic Bioactives from Peganum hermala Leaves Using Response Surface Methodology
Authors: Rahman Qadir , Farooq Anwar , Mazhar Amjad Gilani , Muhammad Nadeem Yaqoob , Mukhtar Ahmad
Published: January 2020

This study investigates the effect of enzyme formulations (Zympex-014, Kemzyme dry-plus and Natuzyme) on recovery of phenolics from Peganum hermala (harmal) leaves, under optimized conditions using response surface methodology. As compared to the other enzyme complexes, the yield (34 g/100g) obtained through Zympex-014-assisted extraction was higher under optimized conditions such as time (75 min), temperature (70°C), pH (6.5) and enzyme concentration (5 g/100 g) using central composite design (CCD). Effectiveness of Zympex-014 towards hydrolysis of P. hermala leaves cell wall was examined by analyzing the control and enzyme-treated leave residues using scanning electron microscope (SEM). GC/MS characterization authenticated the presence of quercetin (1.44), gallic acid (0.23), caffeic acid (0.04), cinnamic acid (0.05), m-coumaric acid (0.23) and p-coumaric acid (0.37 μg/g) as the potent phenolics in Zympex-014 based extract. It can be concluded from the findings of the current work that pre-treatment of P. hermala leaves with Zympex-014 significantly enhanced the recovery of phenolics that supports its potential uses in the nutra-pharamaceutical industry.
Caffeic Acid Phenethyl Ester Reduces Hypoxia-Induced Reactive Oxygen Species and Mitigatates Inflammation in Corneal Endothelial BCE C/D-1b Cells
Authors: Li-Chien Yang , David Pei-Cheng Lin , Han-Hsin Chang , Kwong-Chung Tung
Published: January 2020

Oxygen supply is crucial to the health of avascular human cornea where low-oxygen-transmissible soft contact lenses often cause keratitis upon excessive wear time. Caffeic acid phenethyl ester, an active component of propolis, has anti-oxidative and anti-inflammatory properties. This study investigated the in vitro effects of caffeic acid phenethyl ester on corneal inflammation and its underlying action. We measured NF-κB activity and Dichloro-dihydro-fluorescein diacetate staining to demonstrate that caffeic acid phenethyl ester ameliorates hypoxia-induced inflammation of corneal endothelial cells and reactive oxygen species formation. The results may provide a new strategy to mitigate keratitis by caffeic acid phenethyl ester treatment.
Antihypertensive and Antioxidant Properties of Moringa Oleifera Seed Enzymatic Protein Hydrolysate and Ultrafiltration Fractions
Authors: Taiwo Ayodele Aderinola , Adeola Monisola Alashi , Ifeanyi Daniel Nwachukwu , Tayo Nathaniel Fagbemi , Victor Ndigwe Enujiugha , Rotimi Emmanuel Aluko
Published: January 2020

The aim of this study was to evaluate the in vitro antioxidant and antihypertensive as well as potential cardioprotective properties of peptides generated from enzymatic hydrolysis of Moringa oleifera seed. Moringa protein isolate was digested with alcalase and the hydrolysate fractionated by ultrafiltration using 1, 3, 5, and 10 kDa molecular weight cut-off membranes. Results showed that membrane separation led to decreased free radical (DPPH, hydroxyl) scavenging but enhanced ferric reducing antioxidant power and metal ion chelation properties. The 1–3 kDa peptide fraction was the most active against angiotensin converting enzyme and renin with 6.70% and 24.62% increases, respectively when compared to the hydrolysate. Oral administration (200 mg/kg body weight) to spontaneously hypertensive rats (SHR) resulted in significant decreases in systolic (SBP), diastolic and mean arterial (MAP) blood pressure for the hydrolysates and peptide fractions when compared to the negative control. The 1–3 kDa peptide fraction also showed the greatest (–35 mm Hg) in SBP along with fastest (2 h) reduction of SBP and MAP in the SHR. The hydrolysate produced the most persistent SBP reduction with up to –34 mm Hg after 24 h. However, the longer peptides (>10 kDa) were the most effective (–78 beats per min) in reducing SHR heart rate. The results suggest that the alcalase-hydrolyzed M. oleifera seed peptides could function as potential ingredients for the formulations of functional foods and nutraceuticals with antihypertensive benefits.
The Protective Effect of Sulfated Pachymaran on 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Neuronal Apoptosis in Mice
Authors: Gui-Zhen Gao , Chao Wu , Ke-Feng Zhai , Ling-Ling Shan , Mei-Hong Li
Published: January 2020

Mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine were used to examine the neuroprotective effects of sulfated pachymaran. Male ICR mice were administered 30 mg/kg of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intraperitoneally once a day for 7 days in model group. In sulfated pachymaran treatment groups, different doses of sulfated pachymaran (50, 100, and 150 mg/kg, respectively) were given consecutively after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment in the following 7 days. The apoptosis of neurons in substantia nigra was observed by tyrosine hydroxylase immunostaining and TUNEL (Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) staining. Expression of Bcl-2, and Bax proteins in midbrain and striatum were detected by Western blot. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment significantly decreased the tyrosine hydroxylase-immunoreactive neurons (P < 0.01), increased the TUNEL-positive neurons (P < 0.05). 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine markedly induced downregulation of Bcl-2 expression (P < 0.05, P < 0.01, respectively) and upregulation of Bax (P < 0.05, P < 0.01, respectively) expression in both midbrain and striatum. Sulfated pachymaran restored 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neuronal death in the nigrostriatal pathway, and significantly elevated Bcl-2 expression and declined Bax expression, contributing to the balance between Bcl-2 and Bax proteins. These results indicated that sulfated pachymaran had protective effect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced apoptosis in striato-nigral system in vivo.
Isolation of Epigallocatechin Gallate from Green Tea and its Effects on Probiotics and Pathogenic Bacteria
Authors: Lijun Tu , Hanju Sun , Shudong He , Yongsheng Zhu , Ming Yu , Xianbao Sun , Zuoyong Zhang
Published: January 2020

The aim of this study was to investigate epigallocatechin gallate (EGCG) prebiotics activities systematically which was reported as a bioactive substance. Therefore, EGCG was separated by water extraction, resin purification and prep-HPLC. Then the production of EGCG was confirmed by HPLC and mass spectrometry (MS) analysis and its purify was 97.23%. EGCG extractive and green tea extract (GTE) were further incubated with Bifidobacterium infantis, B. adolescentis, B. bifidum and Lactobacillus acidophilus to study its effect on microbial populations and medium pH. Finally, Escherichia coli, Salmonella, Staphylococcus aureus and Candida albicans were employed as pathogenic bacteria to explore the antimicrobial
activity of EGCG and GTE. The results demonstrated that EGCG extractive could be beneficial for the proliferation of Bifidobacterium and L. acidophilus and also inhibit some pathogenic bacteria. In conclusion, both EGCG extractive and GTE had prebiotics activities and the effects of EGCG extractive were superior to those of GTE.
Safety Evaluation of an Apitherapy Formulation, Bao-Yuan-Ling: Acute and Sub-acute Oral Toxicity in Wistar Rats
Authors: Yanru Sun , Zhenhuang Shen , Zhe Jia , Xiaoqing Miao
Published: January 2020

Bao-Yuan-Ling (BYL) is an apitherapy formulation which is composed of royal jelly, propolis and bee venom. Cardioprotective effects of BYL has been demonstrated, while the toxicity of BYL was not clear. In this study, acute and sub-acute toxicity test of BYL was processed following Organization for Economic Co-operation and Development (OECD) 423 and OECD 407, respectively, in Wistar rats. In acute toxicity test, rats were orally treated with BYL at the single dose of 2000 mg/kg and 5000 mg/kg. No death occurred in the acute toxicity test for 7 days, which indicated the lethal dose 50% value exceeded 5000 mg/kg. In sub-acute toxicity study, rats were treated with BYL at the dose of 250 mg/kg, 500 mg/kg and 1000 mg/kg in a daily base for continuous 28 days. Results showed that female rats were more likely to be affected by BYL in body weight changes, while biochemical indicators of blood serum in male rats were more susceptible to drug effects. However, neither female nor male rats were affected by BYL administration significantly on the organs via hematoxylin-eosin staining analysis. Results suggested that BYL was slightly toxic and clinical use was safe and reliable.
ESTRATEGIAS DIDÁCTICAS Y FORMACIÓN INVESTIGATIVA EN LOS ESTUDIANTES DEL SEGUNDO CICLO DE EDUCACIÓN PRIMARIA INTERCULTURAL DE LA UNIVERSIDAD NACIONAL JOSÉ MARÍA ARGUEDAS.
Authors: Velasquez Quispe Dionicio , Santos Jimenez Ofelia Carmen , Chavez Epiquen Abdias , Moscoso Paucarchuco Ketty Marilú
Published: January 2020

La presente investigación trata de eestablecerla relación que existe entre las estrategias didácticasy la formación investigativa en estudiantes delsegundo ciclo de educación primaria interculturalde la Universidad Nacional José María Arguedas -Andahuaylas 2018. Fue una investigación de enfoquecuantitativa, tipo básica, nivel correlacional, diseñono experimental, y corte transversal. La poblaciónestuvo compuesta por 44 estudiantes del 2do ciclode Educación primaria Intercultural. Los instrumentosutilizados fue encuesta para ambas variables loscuales fueron validados cualitativamente 3 juecesexpertos y la confiabilidad se halló con (Alfa deCronbach = 0.970 y 0.986). Los resultados indicaronun coeficiente de correlación “Tau b” de Kendallde 0.762 y una significatividad estadística de0.010 entre las variables estrategias didácticas yformación investigativa, lo que significa una relacióndirecta entre variables.
COMPROMISO ORGANIZACIONAL Y PRODUCTIVIDAD DE LOS TRABAJADORES EN PROTEGE ORIENTE S.A., PUCALLPA, 2019
Authors: Bollet Ramirez Dr. Frank , Amacifuén Stalaya IIsi , Heredia Estala Lic. Iraida , Chenet Zuta Dr. Manuel Enrique
Published: January 2020

El objetivo del estudio es determinar el grado deasociación existente entre el compromiso organizacionaly productividad de los colaboradores en Protege OrienteS.A., Pucallpa, 2019, las dimensiones e indicadores de lavariable: el compromiso organizacional, fueron adaptadosdel trabajo de Fuentes (2018), de la misma manera loselementos de la variable: productividad de los trabajadores,se adaptaron de Zapata (2018). El tipo de investigaciónfue aplicativo, el nivel descriptivo correlacional, la muestraestuvo compuesta por el total de la población, 54 personas,que trabajaron en la empresa de vigilancia privada, ProtegeOriente SA, Pucallpa. Mediante la prueba de hipótesis,unilateral de cola derecha, utilizándose el coeficiente rhode Spearman se determinó que existe relación directay significativa entre el compromiso organizacional yproductividad de los trabajadores en Protege Oriente S.A.,con la correlación de 0,794, estimada como asociaciónpositiva considerable, en tanto que el nivel de significanciade la prueba, tuvo un valor: s = 0.000 ˂ 0.05, el coeficientefue significativo en el nivel de 0.000, en consecuenciael nivel de confiabilidad es100 % que la correlación seaverdadera y 0.0 % de probabilidad de error
DETERMINACIÓN DE OCRATOXINA “A” EN NUEZ Y ALMENDRA POR CROMATOGRAFÍA LÍQUIDA DE ALTA RESOLUCIÓN CON DETECCIÓN POR FLUORESCENCIA (HPLC-FL)
Authors: Elías Silupu Dr. Jorge Wilmer , García Rivas Plata Dra. Cecilia Edith , Yauris Silvera Mg. Celia Rocio , Pérez Salcedo Mg. Ronald
Published: January 2020

Uno de los problemas en la produccióny almacenamiento de productos agrícolas es lacontaminación por micotoxinas, en especial la Ocratoxina A(OTA) producida por especies de Aspergillus y Penicillium,que puede contaminar cultivos como: cereales, café,cerveza, vino, cacao, frutos secos y otros, consideradopor la FAO una de las fuentes de contaminación másimportantes.El objetivo principal de este estudio fue determinarla contaminación con OTA en la producción primaria denueces y almendras con la finalidad de establecer latrazabilidad de la contaminación utilizando el método deCromatografía Líquida de Alto Rendimiento con detecciónpor fluorescencia (HPLC-FL). La solución de extracciónfue acetonitrilo: agua: ácido acético (50:50:1) v/v, lavalidación del método se basó en criterios de la norma ISOIEC 17025:2005. Después el sobrenadante fue filtrado,secado y reconstituido para ser analizado. Los resultadospresentados, corresponden a las muestras de almendrasy nueces en las que se analizó (semilla, cáscara y pelón)que se encontraron por debajo del límite de detección(BLD) exigidos por la legislación internacional, es decir nose evidenció ningún pico cromatográfico en el tiempo deretención correspondiente para OTA
Pengaruh Carboxymethyl Celulosa Natrium Sebagai Pengental Terhadap Stabilitas Sirup Temulawak (Curcuma Xanthorriza Roxb)
Authors: Sayuti Nutrisia Aquariushinta
Published: January 2020

Abstract : Carboxymethyl celulosa natrium, Curcuma xanthorriza Roxb syrup, Stability. The lack flavor and amylum contain of Curcuma xanthorriza Roxb cause difficulty to make it in to syrup. Carboxymethyl Celulose Natrium (CMC- Na) as a thickener was needed to solve the problem. The study aim to determine the influence of CMC-Na to syrup’s stability Curcuma xanthorriza. The methode was used to determine stability of syrup formulation with three formula with variations in the amount of 1% CMC-Na solution and 80% sucrose solution. Physical stability parameter of the syrup such as viscosity, acidity and organoleptic analyzed by two way anava. The result showed that CMC-Na effected on viscosity, acidity and organoleptic of the syrup. There are influence of CMC-Na to syrup’s stability.
Pengaruh Konsumsi Daun Kacang Panjang Terhadap Peningkatan Kadar Hemoglobin Pada Ibu Hamil Tm Ii Dengan Anemia Di Wilayah Kerja Puskesmas Polanharjo Kabupaten Klaten
Authors: Prastika Dewi Andang , Setiani Onny , Sumarni Sri
Published: January 2020

Abstract: Long Bean Leaves, Haemoglobin, Pregnancy Second Trimester. Anemia in pregnancy is called the 'potencial danger of mother and child' because anemia is a serious problem and need attention from all parties involved in maternal and child health services. WHO reported that the prevalence of anemia in pregnancy in the world amounted to 55% and tended to increase with increasing gestational age. To determine the effect of bean leaf consumption to increased hemoglobin levels of second trimester- pregnant women with anemia in Puskesmas Polanharjo working area. This research was Quasy experiment with a pretest posttest control group design. This research used a treatment group is the group of second trimester-pregnant women with anemia has given long bean leaves consumption as many as 15 respondents and the control group is the group of pregnant women with anemia second trimester without additional Fe tablet intake as many as 15 respondents. There is a difference between the average of hemoglobin levels before the intervention group consumed long beans leaves with an average of hemoglobin levels in the intervention group after consuming long beans leaves. By eating 350 grams of long beans leaves for one month (28 days) may help prevent anemia in pregnant women.
Pengaruh Mengkonsumsi Multiple Micro Nutrient (MMN) Terhadap Peningkatan Berat Badan Ibu Hamil
Authors: Rahayu RD
Published: January 2020

Abstract: MMN, Weight. Pregnant women are one of the vulnerable groups may suffer from anemia because of events that occurred hemodelusi sat pregnancy. MMN is a supplement that contains multivitamins, iron and folate given to pregnant women as one of the Indonesian health ministry programs in an effort to prevent anemia during pregnancy. MMN order to determine the effect on weight gain for pregnant women. The research method to experiment with randomized. The population of 24 male mice. Twenty rats were given MMN. Data analysis using independent t-test. Results: Based on the average value MMN can increase weight gain. There is a difference in weight gain between before and after given MMN.
Pengetahuan, Sikap, Dan Tindakan Mencuci Tangan Yang Benar Pada Siswa Kelas 1 Dan 2 Di SDN 2 Karanglo, Klaten Selatan
Authors: Kusumawardhani Aryani , Syahati Arsita Atmi , Puspaningtyas Safinatul Istiqomah , Rusmanto Aisyah Annas , Kusuma Ledy Septyna Ayu , Septianingrum Septianingrum
Published: January 2020

Abstrak: Pengetahuan, Sikap, Tindakan, Cuci Tangan, Siswa SD. Perilaku mencuci tangan yang tidak benar masih tinggi ditemukan pada anak usia 10 tahun ke bawah. Pada usia tersebut sangat rentan terhadap penyakit. Berdasarkan studi pendahuluan, didapatkan bahwa kebiasaan cuci tangan siswa SDN 2 Karanglo, Klaten Selatan belum sesuai dengan cara mencuci tangan yang baik. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan, sikap, dan tindakan mencuci tangan yang benar pada siswa kelas 1 dan 2 di SDN 2 Karanglo, Klaten Selatan, Klaten tahun 2016/2017. Metode dalam penelitian ini merupakan jenis penelitian deskriptif. Variabel pada penelitian ini adalah pengetahuan, sikap dan tindakan. Responden pada penelitian ini adalah siswa kelas 1 dan 2 yang berjumlah 29 siswa. Pada penelitian ini digunakan instrumen berupa kuesioner. Data primer diperoleh dari lembar kuesioner dan data sekunder diperoleh dari absensi siswa dan literatur. Hasil penelitian, pengetahuan siswa tentang mencuci tangan yang benar termasuk dalam kategori baik yaitu sebanyak 20anak (69%) dan kategori cukup sebanyak 9 anak (31%). Sikap siswa tentang cuci tangan yang benar termasuk dalam kategori baik yaitu sebanyak 29 anak (100%). Tindakan siswa tentang cuci tangan yang benar termasuk dalam kategori baik yaitu sebanyak 28 anak (97%) dan kategori cukup sebanyak 1 anak (3%). Kesimpulanya pengetahuan, sikap, dan tindakan mencuci tangan yang benar pada siswa kelas 1 dan 2 di SDN 2 Karanglo, Klaten Selatan dikategorikan baik.
Evaluasi Mutu Salep Dengan Bahan Aktif Temugiring, Kencur Dan Kunyit
Authors: Lestari Titik , Yunianto Bambang , Winarso Agus
Published: January 2020

Abstract : Quality Evaluation, Ointments, Kaemferia Galanga, Curcuma Domestica, Curcuma Heynena. Indonesia is a country with very high biodiversity. In the high diversity of the stored potential nutritious plants that can be explored and exploited further. Community began to realize the use of chemicals to cope with life problems, especially health problems, in addition to expensive, can also result in less side effects both for humans. This study used a extract Curcuma domestica, Kaemferia galanga, and Curcuma heynena as active ingredients skin ointments. This study intends to determine the third quality evaluation ointment. This type of research was descriptive. Quality evaluation results showed nearly the same physical properties, except for the parameters of the spread, and viscosity. Test result of physical standart compliant was organoleptic, pH, power spread and viscosity.
Penggunaan Tanaman Herbal Untuk Kesehatan
Authors: Yulianto Susilo
Published: January 2020

Abstract: The use of herbs, for health. Herbs are plants that can be used as drugs both leaves, stems, or roots. Herbs is partly used by the community for traditional or alternative medicine. Besides, the herb also has the advantage, that does not have side effects, treatment can be carried out by family members sendiri.Tanaman is an alternative herbal treatment that has been done by the people of Indonesia have traditionally. The successful use of herbal plants is strongly influenced by people's knowledge about the benefits of each type of medicinal plants, especially herbs that have been studied empirically. It is also influenced by how the use of each herb for a variety of different diseases. This study aims to determine the use of herbs for health. This research method is descriptive, with a sample of 53 respondents drawn by simple random sampling technique. The data collection conducted direct interviews with respondents and the open-air observation. Research instrument used was a questionnaire. The result showed that all respondents had been using herbs for health. The conclusion of this study was the use of herbs for health still needs to be improved further by providing the knowledge, awareness, willingness and ability of thecommunity.
Pengaruh Kontrasepsi Suntik DMPA Terhadap Kenaikan Berat Badan Tikus Betina Galur Wistar
Authors: Prihati Dwi Retna
Published: January 2020

Abstract: DMPA Injectable Contraception, Body Weight. The purpose of this study to determine the effect of contraception DMPA injection to BB in female blood wistar strain female. The benefits of this study are expected to increase public knowledge about injectable contraception especially related to the side effects of weight gain. This type of research is an experimental laboratory. Research design Randomized pre-post test group with control, the sample size of 10 adult female mice Wistar strain divided into 2 groups. Data were analyzed by independent T test. Significant value of p <0.05. The result of this research is there is significant difference between control group and DMPA contraception treatment group (p = 0,008). In conclusion contraceptive DMPA affects body weight wistar female rat strain.
Uji Fisik Sediaan Gel Ekstrak Tongkol Jagung (Zay Mays L)
Authors: Dewi Indri Kusuma , Rachmawati Mey , Ma'rifah Fathiya Abdinnisa' , Susilowati Puspita
Published: January 2020

Abstract Background : Corn cobs have the potential to protect the skin, so far the research has only been limited to testing the extracts and has not been formed in a cosmetic preparation. Gel is a cosmetic preparation that is ideal for sunscreens because it is less oily, not sticky, soft, elegant, can form a layer of film that adheres well and protects the skin, and evaporation of water content creates a soothing and pleasant effect. Method: The method is used to determine the physical appearance of the gel with organoleptic parameters, homogeneity, dispersion and absorbency. Result: The purpose of this study was to determine the results of the physical test of sunscreen gel preparations from corn cobs extract (Zea mays L). Conclusion: The physical test results from the sunscreen gel extract of corn cobs extract (Zay Mays L.) had the results of organoleptic test, homogeneity test, spreadability test and adherence to the standard.
Perbedaan Kecukupan Asi Antara Akseptor KB Suntik Kombinasi Dengan KB Suntik Progestin Pada Ibu Menyusui 0-6 Bulan Di Wilayah Kerja Puskesmas Sambirejo Sragen
Authors: Adnara Chelia Ercy , Prihati Dwi Retna , Istikhomah Henik
Published: January 2020

Background: Nursing mothers who do not want to get pregnant anymore need safe contraception, do not interfere with the breastfeeding process and do not affect breast milk production. Injection contraception is divided into two, namely combined injection family planning and progestin injection family planning. Combined injection family planning contains the hormone estrogen which can reduce the amount of breast milk production, while injectable progestin family planning contains the hormone prolactin which can stimulate the production of breast milk glands. One of the factors that influence the adequacy of breast milk is the use of contraception. Method: Type of observational research with cross sectional design. The sample in this study were all breastfeeding mothers who used injection contraception in the work area of ​​Sambirejo Health Center Sragen in September to November 2018 as many as 62 people. Total sampling technique, chi square analysis. Results: Characteristics of acceptor age, namely 20-35 years as many as 52 people (83.9%) education namely high school as many as 30 people (48.4%), occupations namely housewives as many as 46 people (74.2%) and parity is primipara 33 people (53.2%). The adequacy of breastfeeding in breastfeeding mothers who use combined injection contraception is mostly 16 people (25.8%) and not enough as many as 12 people (19.4%). The adequacy of breastfeeding in breastfeeding mothers who use the progestin injection contarction is mostly 32 people (51.6%) and not enough as many as 2 people (3.2%). The chi square test results p = 0.001 (p <0.05). Conclusion: There is a difference in the adequacy of breastfeeding between family planning injection acceptors combined with Progestin injections in breastfeeding mothers 0-6 months in the working area of ​​Sambirejo Sragen health center.
Pengaruh Terapi Non Farmakologi Dengan Media Murrotal Al-Qur’an Kombinasi Senam Dysmenorrhea Terhadap Penurunan Nyeri Haid Di Panti Asuhan Sejahtera Aisyiyah
Authors: Hamdiyah Hamdiyah
Published: January 2020

Reproductive health is an important part of general health and main characteristic to increase the degree of human health from childhood, and most important is adolescence and adulthood. And determine the level of reproductive health for women dan men. This can affect future generations’ health. Women who have entered puberty will who experienced menstruation, most of women will experience discomfort or painful periods and  usually called by dysmenorrhea. Dysmenorrhea Management can used by pharmacological and non-pharmacological therapy  that have been carried out as an effort to overcome dysmenorrhea such as analgesic drugs, hormonal therapy, non-steroidal prostaglandin drugs, and dilatation of the cervical canal.

This therapy can Addiction and Negative Effects and drug side effects is dangerous for patient  while non-pharmacological therapy common is relaxation  therapy with  listening to music, acupuncture, acupressure, sports, and spiritual therapy. One of  non-pharmacological therapy is gymnastics / sports, and spiritual therapy that is usually by dzikir also listening the holy Quran recitation able to provide a relaxing effect because it can activate the relaxing effect because it can activate the hormone endorphin.The research is quasi eksperimental model with  the pretest- posttest two group design. The sample of this research that adolence  in Panti Asuhan Sejahtera Aisyiyah Pangkajene, Sidrap. Respondent recruitment by using purposive sampling. The data analysis used independent t-test.The research result from independent t-test, The results showed there is a significant effect of non farmakologi therapy with  murottal therapy (Al-Qur'an) combination  dysmenorrhea gymnastics in reducing pain level.. Results of the analysis (Pv = 0.000) <α (0.005) each month is the first month, the second month and the thirdh month.
Efektivitas Daun Sirsak Terhadap Penurunan Tekanan Darah Pada Penderita Hipertensi Di Wilayah Kerja Puskesmas Balibo Kabupaten Bulukumba
Authors: Safruddin  , Alfira Nadia
Published: January 2020

Hypertension or high blood pressure is an increase in normal blood pressure in blood vessels. Hypertension sufferers in addition to high risk of suffering from heart disease, are also at risk of suffering from other diseases such as nerve and kidney disease. Treatment of hypertension can be done by pharmacological and nonpharmacological methods. Lately the treatment is often done by people who consume herbal plants. The ability of herbs to control hypertension has been proven by our ancestors during various years. One of the herbal plants proven to be able to reduce blood pressure is soursop leaves. Research Objectives is To measure the level of risk of soursop to decrease blood pressure in patients with hypertension in the Work Area of ​​Balibo Health Center, Kindang District, Bulukumba Regency. Research Methods is Quantitative research methods using pre-experimental designs, namely experimental research designs consisting of one group pretest - posttest design. The population in this study were all hypertensive sufferers who were in the work area of ​​Balibo Community Health Center, Kindang District, Bulukumba District, as many as 567 people, 15 samples were taken with successive sampling techniques. The instrument used was a sphygmomanometer, produced in the observation sheet. Research Results is There is a problem with soursop leaves in reducing blood pressure in hypertensive patients in the Puskemsas Balibo work area, Kindang District, Bulukumba Regency. This was discussed with the results of the Wilcoxon systole blood pressure obtained p <α (p = <0.001), and diastolic blood pressure obtained p value <α (p = 0.002). Conclusion: There is an effect of soursop leaves on blood pressure reduction in hypertensive patients in the work area of ​​Puskemsas Balibo, Kindang District, Bulukumba Regency. Suggestion is expected that hypertension sufferers and health workers to use soursop leaves as a treatment for hypertension.
Obesitas Dan Pekerjaan Orang Tua Dengan Prestasi Siswa SMA Negeri 3 Bulukumba
Authors: Siringoringo Edison , Asri
Published: January 2020

According to World Health Organization (WHO) in 2015 had 42 million children who were overweight. This figure rose 31 million from 2000. Obesity adolescents tend to have an impact on learning achievement and on their health.The purpose of this study was stundents in senior high school 3 bulukumba. 265 respondents sampling technigue used consecutive sampling technigue this type of research is an analytical study with a cross sectional approach. The test used for the relationship of obesity whit student achievement is the fisher’s exect test while the test used for the relationship of parental work with student achievement is the kolmogorov smirnov test.The results of the study are respondents with type 1 obesity with good achievement scores of 27 respondents (87.1%) and achievement scores of less than 4 respondents (12.9%). While respondents with type 2 obesity with good performance scores were 9 respondents (56.2%) and achievement scores were less than 7 respondents. And the work of parents as PNS with a good achievement value of  15 respondents (93.8%) and less achievent scores of 1 respondents (1.6%). While respondents with the work of parents as entrepreneurs with good achievement scores of 10 respondents (55.6%) and achievement scores of less than 8 respondents (44.4%). Then the work of parents as farmers with good performance scores as many as 11 respondents. While the achievement score is less than 2 respondents (3.8%).The conclusion of this study is theres is a relationship of obesity with the achievement of students in senior high scholl 3 Bulukumba between parental work and the achievement of students in high school 3 Bulukumba. As for the suggestion in this study can add library references and student insights on Sitekes Panrita Husada Bulukumba.
Identifikasi Kandungan Boraks Pada Bakso Di Kabupaten Bulukumba
Authors: Nur Arfiani , Artati
Published: January 2020

The background of this research is that Borax is a chemical compound called sodium tetraborate (NaB407 10 H20). If dissolved in water it will become hydroxide and boric acid (H3B03). Borax is often misused as an additional ingredient not permitted in foods that are adapted to Permenkes RI No. 1168 / Menkes / Per / X / 1999 concerning food ingredients. The purpose of this study was to determine the content of borax in meatballs in the district of Bulukumba. This type of research is a laboratory experimental study using qualitative test methods. The sample of this study was that curcumin paper did not produce changes in color on curcumin paper, the color of curcumin paper remained yellow indicating that the sample did not contain hazardous borax.
Uji Bioaktivitas Ekstrak Buah Sawo Manila (Manilkara Zapota) Terhadap Pertumbuhan Bakteri Salmonella Typhi
Authors: Salnus Subakhir , Nurhamsiah
Published: January 2020

This research was conducted bioactivities by using raw fruits of sapodilla sapota (Manilkara zapota) as a drag growth media of Salmonella typhi bacteria causes typhoid fever disease. Salmonella typhi is a species of bacteria that are gram-negative bacilli shaped, facultative, aerobic, moving with a single pertrich. Sapdilla sapota has antimicrobial activity against Salmonella typhi, because it contains a variety of secondary metabolite compounds such as saponins, tannins and flavonoids.  The purpose of this research was to know how efective the raw fruits of sapodilla sapota (Manilkara zapota) against the growth of Salmonella typhi. This is an laboratory research by using diffusion test method. The sample of this research is to extract the fruit of sapodilla sapota (Manilkara zapota) crude. The results of this research, are 35% concentration of extract cannot be formed drag zone (0 mm), but in 40, 45, 50 and 55% of concentration there are had drag zone (9 mm, 13 mm, 13.5 mm, and 18 mm). this can be said that the raw fruit of sapodilla sapota extract can inhibit the growth of Salmonella typhi bacteria can be done, then the next extension to the sufferers of the disease typhus to consume raw fruits of sapodilla sapota so that can reduce the growth of bacteria.
A Elite ruralista no parlamento:
Authors: Silva Lima Mayrá
Published: January 2020

O artigo traz uma análise das principais caraterísticas da Bancada Ruralista na Câmara dos Deputados e sua atuação como elite política. Os dados foram obtidos através das biografias publicadas pela Câmara Federal em seu portal na internet, sendo considerada a composição da Frente Parlamentar da Agropecuária (FPA) durante as 54° e 55o legislaturas. A atuação desta bancada como elite política considera não somente a sua organização numérica, mas também a mobilização de vieses capazes de impedir que interesses antagônicos ganhem espaço de deliberação política. Para exemplificar, utiliza-se as notas taquigráficas da CPMI da Terra na busca dos vieses construídos dentro do Parlamento.
Des(a)fiando memórias:
Authors: Alves Ramiro Patrícia , Alves de Almeida Olivia
Published: January 2020

O presente artigo tem como objetivo desfiar (e desafiar) as memórias sobre a história de um dos assentamentos pioneiros do Estado de São Paulo, a Gleba XV de Novembro, implantado na região do Pontal do Paranapanema em 1984. Para tanto, utilizando da metodologia da história oral, entrevistamos as mulheres da Organização das Mulheres Unidas da Gleba XV de Novembro (OMUS). Partimos do pressuposto de que pensar a temática de gênero atrelada às memórias de mulheres sobre o processo de luta e conquista da terra é imprescindível para que se possa compreender a reforma agrária sob diferentes óticas. Seus depoimentos mostram que, ainda que silenciadas na construção da história oficial produzida pelo meio acadêmico, estas mulheres foram fundamentais para a efetiva conquista da terra.
Representações sociais sobre a extensão rural no contexto da comunidade remanescente do quilombo Nova Jatobá, Curaçá-BA
Authors: Moreira dos Santos Danilo , De Almeida Araújo Nilton , Ribeiro Freitas Helder
Published: January 2020

Este artigo, fruto da dissertação de mestrado, aborda Representações Sociais de quilombolas e extensionistas acerca da extensão rural e identidade étnica no contexto da Comunidade Remanescente de Quilombo Nova Jatobá, Curaçá-BA. Seguindo uma abordagem qualitativa, tendo como instrumentos a entrevista semiestruturada e a observação, e com base na Teoria das Representações Sociais e na Teoria da Análise de Discurso francesa, apreendem-se as representações de 13 participantes relacionados como usuários, praticantes e espectadores em um contexto de ações de desenvolvimento rural executadas por entidade não governamental. Demonstra-se, acerca dos quilombolas, como a cultura e a identidade influenciam suas representações da realidade. Nota-se uma polissemia nos discursos mobilizados, inclusive com a explicitação de sentidos convergentes entre os dois grupos, que buscam estabelecer primordialmente uma valoração positiva da identidade étnica, da Extensão Rural e da atuação extensionista, porém explicitando sentidos outros a partir do não dito que atravessa o dizível e mesmo dos contrastes presentes no discurso. Representações negativas também se relacionam à significação da realidade, como no caso da identidade quilombola, acerca da qual se explicita uma influência de princípios contrários à noção de “neutralidade racial” nos processos de interação, confrontantes com o próprio sentido de autoafirmação identitária.
Condicionantes e diversidade de estratégias entre agricultores familiares no Noroeste do Rio Grande do Sul
Authors: Casagranda Zanella Francis , José de Medeiros Torres Ewerton , Leonardo Becerra Bonza Andrés
Published: January 2020

Objetiva-se analisar sistemas produtivos e estratégias de reprodução social dos agricultores familiares do município de Derrubadas, localizados no noroeste do Estado do Rio Grande do Sul. Observa-se a diversidade interna da ampla categoria social, analítica e política da ‘agricultura familiar’ em um território onde este setor ocupa um espaço marginal perante os agricultores patronais. A abordagem teórico-metodológica utilizada é a Análise-Diagnóstico de Sistemas Agrários, somada aos aportes da categoria ‘estratégias de reprodução social’ desde Pierre Bourdieu. Os resultados apontam que as estratégias assumidas pelos grupos sociais do mundo rural têm relação com as posições objetivas incorporadas historicamente. Sistemas de produção que designamos como ‘ampliados’, ‘intensivos’ e ‘pluriativos’ caracterizaram as unidades de produção familiares/marginais estudadas, ilustrando os condicionantes e a diversidade de posições nas estruturas espaciais/sociais.
POLÍTICAS PARA LA AGRICULTURA FAMILIAR EN EL PERÚ:
Authors: Zegarra Eduardo
Published: January 2020

O artigo analisa a evolução das políticas públicas orientadas à agricultura familiar durante a última década no Peru. A partir de uma tipologia das políticas agrárias, identifica-se que no Peru ainda predominam políticas do tipo generalistas que, ainda que tenham implicações para a agricultura familiar, não conformam um conjunto coerente e articulado para atender as demandas e necessidades dos agricultores familiares. Também se propõe um marco conceitual e algumas considerações visando a superação desta limitação e o desenho de uma política específica para o desenvolvimento da agricultura familiar em um contexto de alta heterogeneidade social e geográfica, como é o caso do Peru.
A (RE)PECUARIZAÇÃO DO SEMIÁRIDO NORDESTINO:
Authors: Branquinho Nunes Aldo Manoel
Published: January 2020

Com esse trabalho, pretendeu-se analisar alguns elementos da dimensão cultural que fundamentam o processo de expansão da pecuária no Sertão nordestino aqui denominada de (re)pecuarização. Foram focalizados alguns eventos culturais que se realizam em dois municípios da Microrregião do Pajeú, no Estado de Pernambucano e que, de certa maneira, atualizam a simbologia do rural a partir da atividade pecuária. Para tanto, utilizou-se de um aparato teórico-metodológico que combinou observação participante e análise de discursos para compreender como vaquejadas, missas com vaqueiros, cavalgadas, pegas de boi e laços de bodes fundamentam as escolhas produtivas em favor da pecuária e legitimam socialmente essa atividade como a imagem preferencial do rural nordestino e como parte do estilo de vida de indivíduos.