bluuebunny/crossref_metadata_2025 huggingface dataset:
BRAND IMAGE MEMEDIASI HUBUNGAN E-COMMERCE DENGAN KEPUTUSAN PEMBELIAN KONSUMEN
Authors: Pratiwi Ni Kadek Anggi , Ekawati Ni Wayan
Published: July 2020

Pariwisata di Bali berkembang semakin pesat sehingga persaingan penyedia jasa penginapan juga semakin ketat, mulai dari hostel hingga resort mewah. Tujuan dari penelitian ini adalah untuk menjelaskan pengaruh e-commerce terhadap keputusan pembelian, e-commerce terhadap brand image, brand image terhadap keputusan pembelian, dan peran brand image memediasi hubungan e-commerce dengan keputusan pembelian. Penelitian ini dilakukan pada konsumen hotel THE HAVEN Bali Seminyak yang memesan kamar hotel menggunakan website resmi hotel. Ukuran sampel yang diambil sebanyak 136 responden dengan metode purposive sampling. Teknik analisis yang digunakan adalah analisis path. Hasil penelitian menemukan bahwa e-commerce berpengaruh positif dan signifikan terhadap brand image. Penelitian ini juga menemukan bahwa masing-masing variabel, yaitu e-commerce dan brand image berpengaruh positif dan signifikan terhadap keputusan pembelian. Brand image juga berperan sebagai pemediasi hubungan antara e-commerce terhadap keputusan pembelian.

Kata kunci   : e-commerce, brand image, keputusan pembelian
AGROECOSYSTEMS OF LAND SUITABILITY IN SUB-DISTRICT OF SOUTH KUTA FOR COMMODITY DEVELOPMENT HORTIKULTURA FRUITS IN BADUNG DISTRICT, BALI
Authors: Trigunasih Ni Made , Dibia I Nyoman
Published: July 2020

This study aims to: (1) to know  the suitability of the land for the development of several fruit horticultural commodities in the Sub-district of South Kuta, (2) determine the suitability of land in agroecosystem and its limiting factors, (3) provide ecommendations for land management in the study area. The study used a field survey method with the determination of observation samples carried out in a stratified purposive sampling with land units as the strata. Land quality/characteristics as a determinant of land suitability observed include: annual mean temperature, water availability; rooting media; availability of oxygen; nutrient retention, CEC, BS, pH, and organic matter; nutrients available; erosion; flood hazard; land preparation. Land suitability assessment is done by matching the land quality with the growing requirements for the plants evaluated. The results showed that the actual land suitability for food crops of fruit horticulture (citrus, mango, starfruit, banana, sapodilla, grape, klengkeng, papaya, grain guava, guava, jackfruit, soursop, avocado, srikaya, breadfruit and pineapple) belonged according to conditional marginal suitable (S3), until not appropriate (N) with the quality of the land as a limiting factor are: rooting media (effective depth of soil); land preparation (surface rocks and rock outcrops); erosion hazard; and nutrient availability (especially N-total and P-available). The assumption is that some land quality/characteristics that are as limiting factors can be improved, then the suitability of the potential land is quite suitable (S2) to marginal suitable (S3) with the quality/characteristics of the land as a limiting are: availability of water (long dry months), rooting media (effective depth), land preparation (surface rocks, rock outcrops), and nutrient retention (rather high soil pH). Increased land productivity in the study area can be done by improving land management by providing inputs such as: the addition of sufficient organic material, adition of fertilizer containing elements of N (ZA), and fertilizer containing elements of Potasium (SP36), taking conservation measures in the form of making terraces on sloping lands.
THE ROLE OF ORGANIC MATTER ON IMPROVEMENT OF THE PROPERTIES OF KUSAMBA BEACH SAND SOIL, DAWAN SUB-DISTRICT, KLUNGKUNG REGENCY, BALI FOR WATERMELON (Citrullus lanatus Tunb) CULTIVATION
Authors: Wiyanti Wiyanti , Soniari Ni Nengah , Dibia I Nyoman
Published: July 2020

The study on The Role of Organic Matter on Improvement of The Properties of Kusamba Beach Sand Soil, Dawan Sub-District, Klungkung Regency, Bali For Watermelon (Citrullus lanatus Tunb) Cultivation was conducted in the green house of Agriculture Faculty, Udayana University, Bali. The aim of this study was to determine the role of organic matter in the soil properties of beach sand (Entisol type) to increase crop productivity of watermelon. The research used pot experiment with completely randomized design (CRD) method. The treatments used was organic fertilizer of waste cattle with base fertilizer (N, P, K). The dosage of organic fertilizer were: P0 (20% of the weight of soil); P1 (40%); P2 (60%), and P3 (80%). Each treatment was repeated three times, so in total were 12 pots treatment. Organic matter can decrease bulk density, soil permeability, and increase the total porosity of the soil. It was also able to increase total nitrogen, availability P in soil, dry weight of crop and the weight of the fruit at harvest. The highest bulk density was at P0 and the lowest was at P3 or decreased by 23.17%. The soil porosity increased by 7.98%, while the soil permeability decreased by 26.29%. The highest of total Nitrogen and P availability at treatment P3 which increased by 100% and 135.33% repectively when compared with P0. The dry weight of crop and weight of fruit at harvest increased of 48.81% and 97.70% when compared with treatment of P0.
IDENTIFICATION OF CITRUS WHITEFLY, HOST OF ENTOMOPATHOGENIC FUNGI (ASCHERSONIA PLACENTA) IN BALI INDONESIA
Authors: Merthaningsih Ni Putu , Sudiarta I Putu , Wirya Gusti Ngurah Alit Susanta
Published: July 2020

One of the pests of citrus is whitefly that, causes damage directly or/and indirectly to the citrus production. To control whitefly the farmer usually use chemical insecticide, however the utilization of chemical insecticide has been reported to haves many negative effect. To minimize the utilization of chemical insecticide, the environmentally friendly method is needed. One of the method is to utilize the natural enemies. Natural enemies are including, parasitiod, predator as well as insect pathogen (entomopathogen). In 2017 entomopathogenic fungi Aschersonia placenta was found to be associated with citrus whitefly in Bali Indonesia. However the species of whitefly has not been identified. In this research the identification of whitefly, the host insect of A. placenta was conducted based on morphological and molecular identification. Morphological identification of whitefly use puparial stage, started with sample preparation by Slide Mounting Protocol. The target  of mitochondrial cytochrome c oxidase subunit I (mtCOI) gen was successfully amplified (700 bp) by PCR using forward primer LCO 5'GGTCAACAAATCATAAAGATATTGG3' and reverse primer HCO 5'TAAACTTCAGGGTGACCAAAAAATCA3'. The phylogenetic analysis using software ChromasPRO, Molecular Evolutionary Genetics Analysis (MEGA 5.05), PAUP, BioEdit, and TreeGraph2 was conducted. The result shows that the mtCOI sequence of P. minei from Bali (LC491421) has the highest percentage among others with MK421974 P. minei (score homology 96%). The morphological recognition and sequence analysis show that the species of citrus whitefly is  Paraleyrodes minei.
PELATIHAN PEREGANGAN DAN ISTIRAHAT AKTIF MENURUNKAN KELUHAN MUSKULOSKELETAL, KELELAHAN MATA DAN MENINGKATKAN KONSENTRASI KERJA KARYAWAN REKAM MEDIS RUMAH SAKIT SANGLAH DENPASAR
Authors: Indrawati Eko Putu , Tirtayasa I Ketut , Adiatmika I Putu Gede
Published: July 2020

Currently, the department of medical recording of Sanglah hospital have utilizedcomputerization system. So must of the medical the record of patiens was organized by the devices. Some of physical complaint always felt by operator computer, especially on their neck, shoulder, arm, wrist, hand and eyes that could be annoyed the quality and productivity of the employees. The stretching training and active rest should be done to the employees of the department of medical recording of Sanglah hospital decreasing all of the complaints and could be increasing their the work concentration. Has the studies to the sample subjek an employees BMR, sampel were 20 people  give treatmentinmy form training stretching and active rest. Variabel measure is complait musculoskeletalm eye fatique and concentration work. Resul treatmen betwen before working and after work for the Periodic I and Periodic II compared and analyzed statistically.In PI, the average score of musculoskeletal disorder is 77.36, eye fatigue is 67.90, and the work concentration which cover : speed 26.03, accuracy 18.01, and constancy 7,22. Mean while, in PII the average of score musculoskeletal disorder is 45.56, eye fatigue is 52.25, and the work concentration which cover : speed 15.00, accuracy 13.50, and constancy 6.23. According to that score could be knowing that the stretching training and active rest was decrease musculoskeletal disorder about 71.98%, eye fatigue 46.73% and the work concentration which cover : speed 80.06%, accurancy 61.89%, and constancy 40.08%. Which is in statistic this study was significantly p<0,05Therefore, could be concluded that stretching training and active rest decreasing musculoskeletal disorder and eye fatigue, and increasing the work concentration of BRM employees of Sanglah hospital. By doing so, that stretching training and active rest advisably to starts to be implemented in order to all of work activities of BMR employees of the hospital because the evident could be able to decrease musculoskeletal disorder, eye fatigue, and in order to increase employees” the work concentration
GAMBARAN FUNGSI PARU DAN KELUHAN MUSKULOSKELETAL PADA PEKERJA PENGISIAN LPG (LIQUIFIED PETROLEUM GAS) DI DENPASAR
Authors: Nugraha Agung I Gusti Ngurah , Adiputra Luh Made Indah Sri Handari
Published: July 2020

LPG filler workers are the individuals that susceptible to having a lung function abnormality and musculoskeletal disorders due to their type of work. If those problems happen, it could affect productivity and quality of life of the workers. The purpose of this research is to determine the description of lung function and musculoskeletal disorders on LPG filler workers in Denpasar. This research was using a cross-sectional study involved 45 people as the subjects. In this research, the subjects are tested their lung function using spirometer and filled a Nordic Body Map questionnaire. The spirometry test showed 23 people (51%) are having lung function abnormality as follows: 17 subjects (38%) with restrictive lung, 4 subjects (9%) with obstructive lung, and 2 subjects  (4%) with mixed lung abnormality. Musculoskeletal disorders are mostly experienced on waist 35 subjects (78%), left knee 22 subjects (48%), back 22 subjects (48%), upper neck 21 subjects (47%), and lower neck 21 subjects (47%). Those problems might be associated with working position and work posture during filling the LPG. The characteristic of lung function on LPG filler workers was found mostly restrictive lung function. In the musculoskeletal disorders, the prevalence is mostly on the waist, left knee, and on the back.
PENGGUNAAN TANGKAI PEGANGAN ROLLER CAT YANG DIMODIFIKASI MENINGKATKAN KINERJA PENGECAT PLAFON RUKAN DI DENPASAR
Authors: Haryawan I Gusti Agung , Sutjana I Dewa Putu , Sutajaya I Made
Published: July 2020

Buildings development is very glowing recently.  This also has effect on manpower who works at this sector.  Manpower is demanded to have skill according to his field.  Worker at finishing field or especially for ceiling painter needs skill and technique that he should master.  While working the worker always assists by tools and paint materials.  Tools that are used by the ceiling painter have not been refered to antropometry aspect, so it can cause inconvenient in performing the job.  Working with toold that are not accorded to ergonomic principle and working posture that is not physiological can cause fatigue, muscle disturbance, musculoskeletal and increasing working load.  That is why it needs to modify painting roller holder stick.  In that case the worker can work in comfort, safe, healthy, efficient and productive so it can increase productivity. This research was perfomed at office house at Denpasar City.  Type of this research is experimental research by using treatment by subject design by involving 16 samples.  Interval between before treatment and after treatment is given washing out for two days.  Data measured are the working load measured by the increasing of subjective complaint recorded by Nordic Body Map questionnaire, pulses, fatigue and working productivity.  Data of subjective complaint was analyzed by non-parametric statistic test using the Wilcoxon test with significance rate of ? = 0.05, data of pulses as indicator of working load,  working productivity was priorly data normality tested by Shapiro-Wilk Test with significance rate of ? = 0.05.  Data that normal distributed is continued with parametric statistic test using the t-paired test at significance rate of ? = 0.05. Research result shows that there is significant different (p<0.05) to working load variable, musculoskeletal complaint, fatigue and productivity.  At before treatment the average of pulses of ceiling painter is 118.95 + 2.30 dpm, average of musculoskeletal complaint is 78.50 + 5.84, average of fatigue is 74.22 + 388 and average of productivity is 0,070 + 0,017.  Whereas, at after treatment the average of pulses of ceiling painter is 111.89 + 6.58 dpm, average of musculoskeletal complaint is 61.61 + 1.71, average of fatigue is 64.50 + 2.88 and average of productivity is 0,086 + 0,070. Modification of painting roller holder stick turned out to decrease working load for 10,77%, musculoskeletal complaint for 21,51%, fatigue for 13,09%, and productivity is increasing for 22,85%. From discussion above it can be concluded that the modification of painting roller holder stick can decrease working load, musculoskeletal complaint, fatigue, and increase productivity.  In that case, it can be expected that the ceiling painter workers use this painting roller holder stick in order to minimize any complaint raises due to working process
REDESAIN RAKEL DAN PEMBERIAN PEREGANGAN AKTIF MENURUNKAN BEBAN KERJA DAN KELUHAN MUSKULOSKELETAL SERTA MENINGKATKAN PRODUKTIVITAS KERJA PEKERJA SABLON PADA INDUSTRI SABLON SURYA BALI DI DENPASAR
Authors: . Daryono . , Sutjana I Dewa Putu , Muliarta I Made
Published: July 2020

Problems ergonomics in industrial screen printing traditional fabrics such as work attitude unnatural causing musculoskeletal disorders in workers printing. To overcome these problems, especially for fabric printing activity done by redesigning Rakel research and giving active stretching. The purpose of this study was to know the effects of the using redesigning Rakel and active stretching for the fabric screen printing workers to decrease the workload, musculoskeletal disorders and increased work productivity. The study design is the design of the same subject, involving 12 workers printing male, 20-45 years old, between 1-5 years of work experience. Research into two phases. The first phase (I) subjects treated with Rakel without redesigning work and without giving active stretching. The second phase (II) subjects treated with redesigning work Rakel and giving active stretching. Among the two phases of the study, given a wash out period for 2 days and adaptation redesigning Rakel for 4 days, to eliminate carry-over effects. The workload is measured by the method of pulse 10 beats, musculoskeletal complaints measured by a questionnaire Nordic Body Map at 4 Likert scale and work productivity based on the ratio between output and input. Data were analyzed with the Shapiro-Wilk test to determine the normality of the data, paired t-test to test the significance difference variable workload and productivity of work at the significance level ? = 0.05 and Wilcoxon test for variables musculoskeletal complaints. The results showed that redesigning Rakel and provision of active stretching can reduce the workload of 30,3% (p<0.05) and lower musculoskeletal complaints by 16,9% (p<0.05) as well as increasing work productivity by 45,5% (p <0.05). It concluded that the redesign Rakel and provision of active stretching can reduce the workload and musculoskeletal disorders and increase productivity for workers printing. Suggested to the owner of a similar business industry to make good working conditions referring to ergonomic principles, so as to create safer working conditions, comfortable, healthy and productive workers.
Green Cayenne Pepper Production and Marketing Collaboration to Increase Farmer’s Income In East Lombok Regency West Nusa Tenggara
Authors: Bulu Yohanes Gili , Sari Ika Novita , Utami Syvia Kusumaputri , Adnyana I Putu Cakra Putra
Published: July 2020

This study aimed to know: (1) the form of the collaboration done on the green cayenne pepper production and marketing between the farmer and the distributor (2) to analyze the farmer income on the green cayenne pepper production and marketing collaboration. This study was conducted in the central of the cayenne pepper production in East Lombok Regency in March 2017-March 2018. The survey method was employed in this study. The population and participants joined in this study were chosen by the purposive sampling technique. The descriptive analysis was done to merge the quantitative and qualitative analyses used in this study. Results showed that the cayenne pepper production and marketing between the farmer and distributor were productive and able to strengthen their social capital. Technological devices used were also effective in increasing the production of the cayenne pepper as much as IDR 11,343 IDR kg/ha. The farmer gross income mean was reaching IDR 243,210,000/ha, while the mean of the production cost was IDR 80,040,000/ha, therefore the net income was IDR 163/170,000/ha. The cayenne pepper marketing between the distributors in the West Nusa Tenggara and some regencies in Indonesia was done based on trust and some social norms agreed.
Atrial septal defect patients with greater shunts show susceptibility for ventricular arrhythmias
Authors: Yontar Osman Can
Published: July 2020

Objective: Ventricular arrhythmia episodes are not infrequent in patients with atrial septal defect (ASD). Disturbance in cardiac volume and pressures may lead to enlargement and fibrosis in heart. An interatrial volume displacement through septal defect, briefly interatrial shunt, is the major reason for this complication. Prolongation of the interval between the peak and end of the T wave (Tpeak to Tend, Tp-e) on the 12-lead electrocardiogram (ECG), is utilized as a marker of ventricular arrhythmogenesis during last years. The aim of this study was to assess if there is an impact of shunt ratio on ventricular repolarization in patients with ASD by using Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio.

Methods: Patient records of Samsun Training and Research Hospital were retrospectively analyzed. Electrocardiograms of 133 patients, who were diagnosed as ASD between January 2016 and December 2019 were obtained and scanned. ECG intervals were measured. Shunt ratios, right ventricle diameters and volumes were also acquired. Patients were grouped into two by their calculated shunt ratio, ratio of ≥2.0 is accepted as a high shunt group and <2.0 as a low shunt group.

Results: Both groups’ baseline characteristics were similar. Right ventricular dimensions and systolic pulmonary artery pressure were higher in high shunt group. Furthermore, ASD patients with higher shunt ratio had significantly higher ECG measurements than controls, Tp-e: 103.0 (22.1) vs 76.2 (10.2); Tp-e/QT: 0.25 (0.03) vs 0.21 (0.02); Tp-e/QTc: 0.22 (0.03)  vs, 0.17 (0.02); for all p<0.001). Of all ECG parameters; Tp-e (r=0.631, p<0.001), Tp-e/QT (r=0.531, p<0.001) and Tp-e/QTc (r=0.614, p<0.001) had moderate correlation with shunt ratio.

Conclusion: T wave peak-to-end interval is a measure of transmural dispersion of repolarization and accepted as a surrogate for increased ventricular arrhythmogenesis risk. Our findings show that ASD patients whose shunt ratio are ≥2.0 show increased risk for arrhythmias.

Key words: atrial septal defect, electrocardiogram, ventricular arrhythmia, risk, ventricular repolarization
التكامل بين نظام السيطرة النوعية الاحصائية ونظام الانتاج في الوقت المحدد وانعكاسها على تحسين الجودة وخفض التكاليف مع الاشارة الى التجربة اليابانية والامريكية
Authors: Al-Sawaf Mahfoudh H.
Published: July 2020

يشيرالادب الاداري والاقتصادي بأن الكلفة والجودة من العوامل الاساسية التي تؤثر على تنافسية المنظمات محليا ودوليا ، هذا العاملان يعتبران السببان الرئيسيان في عدم التوازن التجاري بين الدول الصناعية المتقدمة وخاصة اليابان والولايات المتحدة الامريكية. اليابان وبعيدا عن التصورات اصبحت عملاقا اقتصاديا واستطاعت من السيطرة على الاسواق عن طريق طرحها منتجات ذات جودة عالية وبأسعار تنافسية، ونتيجة الذعر الذي تولد من عدم التوازن التجاري، فقد تم الانتباه الى حقيقة مهمة تتعلق بالمنتجات اليابانية ، هذه الحقيقة تتمثل في ان جودة المنتجات اليابانية مستمرة في التحسن يضاف اليها انخفاض كلفها الصناعية مقارنة بمثيلاتها في الولايات المتحدة الامريكية. في هذا السياق السؤال الذي يطرح نفسه هو لماذا تحقق اليابان كلف تصنيع منخفضة؟ النظرة التقليدية للعلاقة بين الكلفة والجودة تفترض ان الجودة صفة مميزة والتي تدخل في كلفة الوحدة الواحدة ،والكلفة هي دالة الجودة وتزداد بسبب علاقتها المباشرة بالجودة. هذه الصيغة ترى الجودة كسلعة اقتصادية وتفترض انه بانتاج سلع ذات جودة عالية سيكلف اكثر لانها تحتاج الى مواد افضل،فحص للعمليات والمعدات. هذا التفسير يتقاطع مع النموذج الياباني. في هذا السياق حاول الكثير من الباحثين والمهتمين تفسير الاسباب التي كانت وراء نجاح النموذج الياباني فمنهم من اشار الى كلف التصنيع الواطئة، الاستثمار العالي في التكنولوجيا ، اقتصاديات الحجم، منحنى التعلم بينما يعتقد Deming بأن مفتاح النجاح الياباني هو نظام الجودة الذي يرتكز على برنامج للسيطرة النوعية الاحصائية ((SQCونظام الانتاج الاني (JIT)فضلا عن اسباب اخرى.

ان الهدف الاساس لهذه الدراسة هو التحري عن الفرضية القائلة بأن تطبيق ((SQCو (JIT)سيؤديان الى تحسين جودة المنتجات بشكل جوهري وأن الجودة العالية في النهاية ستخفض من كلف التصنيع.

تناولت الدراسة استعراضا عن الجودة والسيطرة النوعية والانتاج في الوقت المحدد من اجل توسيع الفضاء المعرفي لهذه المفاهيم لتهيئة الارضية الفكرية لمجالات التكامل ومناقشة تأثيرهما على الكلفة والجودة. اخيرا تأشير المشاكل التي يمكن ان تواجه استخدامهما في الصناعات والتوصيات الخاصة باجتياز هذه المشاكل.
Zetcil: Game Mechanic Framework for Unity Game Engine
Authors: Roedavan Rikman , Pratondo Agus , Utoro Rio Korio , Sujana Apriyanti Putri
Published: July 2020

Games are interactive multimedia products that require programming logic and graphic design capabilities in the development process. Game development using Unity Game Engine has become a primary subject in the Multimedia Engineering Technology study program, School of Applied Sciences, Telkom University. In the initial observation, it was found that more than 33% of students have difficulties in making a game using the C# language for Unity. The students understand the Game Design Pattern logic but having difficulty when applying it into programming codes. This research proposes Zetcil, a Game Mechanic Framework that simplifies the game development process for the Unity Game Engine. This framework turned most of the text-based programming commands into visual properties. Based on research for two years, it concluded that the Zetcil could increase 36% of student's confidence to develop games prototype rapidly.
The Future of Global Great Power Competition after the Coronavirus
Authors: Duran Burhanettin
Published: July 2020

Due to the COVID-19 pandemic, the domestic and foreign policy agendas of all countries have been turned upside down. The pandemic has brought new problems and competition areas to states and to the international system. While the pandemic politically calls to mind the post-World War II era, it can also be compared with the 2008 crisis due to its economic effects such as unemployment and the disruption of global supply chains. A debate immediately began for a new international system; however, it seems that the current international system will be affected, but will not experience a radical change. That is, a new international order is not expected, while disorder is most likely in the post-pandemic period. In an atmosphere of global instability where debates on the U.S.-led international system have been worn for a while, in the post-pandemic period states will invest in self-sufficiency and redefine their strategic areas, especially in health security. The decline of U.S. leadership, the challenging policies of China, the effects of Chinese policies on the U.S.-China relations and the EU’s deepening crisis are going to be the main discussion topics that will determine the future of the international system.
Post-Orientalism and Geopolitics: Three Debates that inform Islam and US Foreign Policy
Authors: Khan Muqtedar
Published: July 2020

This article argues that a post-orientalist discourse has emerged over the past few decades to challenge the dominance of orientalism on Western foreign policy thinking towards Islam and the Muslim world. The paper examines the geostrategic thinking of Bernard Lewis, Edward Said, and John Esposito, and their impact on Western perceptions of Islam. The paper submits that while Edward Said exposed the prejudice inherent in orientalist thought, it was John Esposito and a cohort of post-orientalist scholars who engaged in three critical debates with the orientalist to provide a more authentic vision of Islam and a more nuanced picture of the politics of the Muslim world. The paper however concedes that while post-orientalism has triumphed in the academic setting, the orientalist perspective still dominates the policy sphere and continues to shape American foreign policy.
Study the Biological Activity for Shiff Base and Β–Lactam Compounds that Synthesis and Identification from Pyrimidine Derivatives
Authors: Adnan Shaimaa , Neamah Rawaa
Published: July 2020

In This study We are synthesis and characterization of some Schiff base and β- lactam derivatives) by three steps. The First react 2-amino-4-Chloro-6-methyl pyrimidine with 4-amino acetophenone in an acid medium to get shiff base derivative(E)-4-(1-((4-Chloro-6-methyl pyridine-2-yl)imino)ethyl)aniline (1), the second step (1) react with (3,4-dimethoxybenzal dehyde,4-methyl benzaldehyde,4-dimethylamino benzaldehyde,4-bromo benzaldehyde,4–hydroxy benzaldehyde, 4-Nitro benzaldehyde) to get Schiff base derivatives (2-7), the last step (2-7) derivatives react with Chloro acetyl chloride to get –β-lactam derivatives.(8-13) All these compounds are characterization by Fourier Transform Infrared Spectroscopy (FTIR), (1 H-NMR),(13C- NMR). After that study, the biological activity for all these derivatives to word two kinds of bacteria study the Enzymatic and Cancer Cell.
Determination of Ni(II) in Alloy by Spectrophotometric Method with a new Chromogenic Reagent (IDPBS)
Authors: Kadhim Salih H. , Abbas Esraa R. , AL-Da,amy Muneer A. Abbas
Published: July 2020

A new chromogenic reagent 4-((imidazole-2-yl)diazenyl)-N-(pyrimidin-2-yl)benzenesulfonamide was synthesized by the reaction between imidazole and Sulphadiazine as azo reagent and used as new spectrophotometric method with highly sensitive to determined Nickel (II). The reagent reacts with nickel(II) in aqueous solution at pH= 7 to form dark- brown colored complex. The reagent and its complex were identified by Fourier transform infrared (FT-IR), Uv-visible,1HNMR, and 13CNMR spectroscopies and investigate the formula and charge of the prepared complex by molar ratio and molar conductivity measurements. The complex shows λmax at 486 nm with a molar absorptivity 0.3299 x 104 L.mo1-1.cm-1 and Sandell’s sensitivity 0.0177μg.cm-2.Beer’s law is obeyed in the concentration range (0.5–7.6μg.mL-1) of Ni (II) with excellent linearity depicted by correlation coefficient value of 0.9995 with a detection limit of 0.1927μg.ml-1. Recovery and relative error values of precision and accuracy of method were found to be R.S.D.% = 0.39221, Re=98.7% and Erel = -1.3% . The nature of the complex showed that (M:L) ratio was 1:2. This method was applied for the determination of Ni(II) in alloy due to Sensitive, accurate, and rapid spectrophotometric method. The results obtained were compared with the flame atomic absorption spectrometry method, and results are in conformity.
Molecular Identification and Genotyping of Atopobium Vaginae, 16S rRNA Gene from Bacterial Vaginosis Miscarriage Women in Al-Hillah City
Authors: Bunyan Ilham A. , Gatea Asmaa K. , Hameed Alaa K.
Published: July 2020

This study was aimed to determine the Atopobium vaginae associated bacterial vaginosis (BV) in vaginosis women and women with miscarriage. Also other aim, the deoxyribonucleic acid (DNA) sequencing was performed for phylogenetic tree analysis of 16S rRNA gene in local A. vaginae isolates in comparison with NCBI-Genbank global A. vaginae isolates and finally submission of the present isolates in NCBI-Genbank database.
One hundred fifty high vaginal swabs were collected from women with vaginosis(75 samples were taken from married vaginosis women without miscarriage and 75 samples from vaginosis women with miscarriage) from Babylon city hospital and private clinics. The age of patient 15 to 45 years. The sample was collected by disposable swabs, genomic DNA was extracted from these swabs. 16S rRNA gene detection by polymerase chain reaction technique . A. vaginae was isolated on Columbia blood agar supplemented with antibiotic for the first time in Iraq, the study confirmed that 9 (12.00%) and 5 (6.66%) of A. vaginae out of 150 swabs isolated from miscarriage and non-miscarriage vaginosis women respectively. According to the detection of the 16S rRNA gene, the study revealed that 69 (92.00%) and 47(62.66%) of A. vaginae out of 150 swabs obtained from miscarriage and non-miscarriage vaginosis women respectively. Basic Local Alignment Search Tool (BLAST) analysis showed that the 16S rRNA gene shared more than 98–99% sequence compatibility with the sequences of A. vaginae. Furthermore, the phylogenetic tree analysis of the 16S rRNA gene indicated that local A. vaginae (NO.1 and NO. 2 ) isolates shared higher homology with other A. vaginae isolates available in the GenBank. The homology of the nucleotides was between (99.17 and 98.75%) respectively.
The Evaluation of Antiproliferative Effect of Imatinib Derivatives against Breast and Colon Cell-Lines
Authors: Abdul-Rasheed Omar F. , Hussein Ali N. , Mahdi Monther F. , Raauf Ayad M. R.
Published: July 2020

Background: Cancer is considered as one of the major leading causes of death. Tyrosine kinase inhibitors are recognized for their potential antiproliferative effects.
Materials and methods: In the previous study, the authors designed, synthesized, and characterized two imatinib derivatives. These derivatives were biologically evaluated with the utilization of MCF-7, HCT116, and MDCK cell lines.
Results: In respect to the imatinib standard, compound 2b has superior activity against HCT116 cell line (IC50; 15.88 μg/mL against 18.52 μg/mL for imatinib) and an improved cytotoxic activity on MDCK cell line (IC50; 0.654 mg/mL against 0.272 mg/mL for imatinib).
Conclusion: The two synthesized compounds showed biological activity against cancerous cell lines and improved cytotoxic activity against normal non-cancerous cell line with respect to the imatinib standard.
Implementing Educational Game in Pharmacy
Authors: Alshammari Elham
Published: July 2020

Educational games are a teaching strategy that allows students to examine various parts of a game as a method of learning. These are games meant of severe purposes instead of just entertainment. Through their design, education games allow students to gain new skills and knowledge, arouse physical activities, and enhance social-emotional development. Educational games require learners to participate in competitive activities with preset regulations. The objective of this study was to obtain pharmacy students’ satisfaction and perception towards educational game implementation in the classroom setting. The author implemented a prospective study design that involved first-year pharmacy students at Princess Nourah bint Abdulrahman University (PNU). All the students who took part in the study were implementing this type of education for the first time. Thirty students were placed into two teams of 15 and took part in a jeopardy game. All the students were satisfied with the educational game. Key benefits of the game as noted in the study findings include improved cognition functions like memory and reasoning, promoted mental stimulation, learning was better and faster, improved concentration, recall, and thinking, resulted in motivation and more engagement with the team members, resulted in timed responses that were similar to real-life, promoted immediate scoring and there was no need to wait for the outcome, and the learning environment was quite fun. The study can be useful in designing educational games for use in pharmacy courses.
Eukaryotic Probiotic Saccharomyces boulardii Application in Clinical Trails: A Review
Authors: Al-zaidi Rahem E. , Al-Mozan Hanaa D. , Alrikabi Nuha J.
Published: July 2020

Probiotics are live microbes that assist in restoring the symbiotic intestinal gut flora balance, and thus, bestow health benefits to the host. The most commonly used human probiotics are members of the Lactobacillus and Bifidobacterium species. Besides these bacteria, Saccharomyces boulardii, a yeast strain, is also widely used as a probiotic to treat a variety of conditions, including antibiotics-associated diarrhea and recurrent Clostridium difficile infection. A primary advantage of using Saccharomyces boulardii as a probiotic is that it can be used by patients undergoing antibiotic regimen due to its natural resistance to antibiotics. The genetic transfer of antibiotic resistance genes, a frequent event between pathogenic and gastrointestinal tract (GIT) bacteria, is not as frequent between yeast and bacteria. Furthermore, Saccharomyces boulardii is also tolerant to various local stresses such as the presence of gastrointestinal (GI) enzymes, bile salts, organic acids, etc. and can withstand considerable variations in pH and temperature while transiting through the human GIT. Saccharomyces boulardii is known as generally regarded as safe (GRAS)with probiotic activity against a wide range of pathogens. This yeast is often marketed in a lyophilized form, “S. boulardii lyo”, complete sequence of the genome was performed, and a comparative analysis of the genome was performed. From clinical studies, the results of randomized controlled trials in patients repeatedly confirmed the significant positive effect in the treatment of acute and chronic diseases.
Zıtlık Stratejisi veya Göreceli Güç Stratejisi: 2010’lu Yıllarda Türkiye Hisse Senedi Piyasasından Bir Kanıt
Authors: YİĞİT Fatih
Published: July 2020

Hisse senedi fiyatlarının geçmiş verileri kullanılarak gelecekteki fiyatların tahmin edilip edilemeyeceği, finans literatürünün en çok tartışılan konularından biri olmuştur. Finans literatürü, hisse senedi piyasalarında çeşitli anomalilerin varlığına ilişkin fikir birliğine varmıştır. Ancak aşırı tepki anomalisine dair bulgular halen çelişkilidir. Zıtlık stratejisi savunucuları “kazandıranları satma ve kaybettirenleri alma”nın normalüstü getiri sağlayacağını ileri sürerken göreceli güç stratejisi savunucuları tam tersini iddia etmektedir. Bu makale 2010’lu yıllarda Borsa İstanbul verisini kullanarak zıtlık veya göreceli güç stratejilerinin geçerliliğini incelemektedir. Portföy oluşturma dönemlerinde kazandıran portföyler, 2019 haricindeki tüm elde tutma dönemlerinde negatif normalüstü getiri sağlarken portföy oluşturma dönemlerinde kaybettiren portföyler tüm elde tutma dönemlerinde pozitif normalüstü getiri sağlamaktadır. Bulgular aşırı tepki hipotezini desteklemekte ve orta vadede kaybettirenlerin kazandıranlardan daha iyi performans gösterdiğini işaret etmektedir. Borsa İstanbul orta vadeli fiyat geri dönüşleri göstermekte ve yatırımcılar zıtlık stratejisi kullanarak normalüstü getiriler sağlayabilmektedir. Böylece Türkiye hisse senedi piyasasında zayıf formda piyasa etkinliğinin ihlali ortaya çıkarılmıştır. Aşırı tepkinin asimetrik olduğu ve kaybettirenlerdense kazandıranlarda gözlemlenebileceği sonucuna varılmıştır.
Photoactivation of Cryptochromes Invokes Competing Inter- and Intramolecular Electron Transfer
Authors: Tazhigulov Ruslan N. , Provazza Justin , Coker David , Bravaya Ksenia B.
Published: July 2020

Growing experimental and theoretical evidence points to the key role of cryptochrome proteins in magnetoreception by migratory birds and insects. Cryptochrome photoactivation is achieved through a cascade of electron transfer events leading to formation of a long-lived spin-correlated radical pair. The electron transfer cascade is initiated by photoexcitation of the FAD cofactor and subsequent electron transfer through three conserved tryptophan residues, the so-called tryptophan triad. Presence of ATP was shown to increase the yield of the semireduced form of FAD. While electron transfer through the tryptophan triad is well characterized by both theoretical and experimental methods, the effects of ATP binding are still not well understood. The present work aims to unravel the mechanism of ultrafast photoinduced electron transfer in a cryptochrome protein with a focus on effects of ATP on the FAD photoreduction process. Photoinduced electron transfer is described by means of state-of-the-art theoretical methods: a hybrid quantum-classical polarizable embedding scheme is utilized to accurately parameterize a generalized local excited/charge transfer state system-bath model Hamiltonian and the photoinduced electron transfer process is described by a semiclassical path integral-based dynamics method. The results draw attention to the crucial role of the intramolecular electron transfer from adenine to the flavin moiety of the FAD cofactor for formation of the semireduced form of FAD, providing an explanation for the increased yield of the semireduced form in the presence of the cellular metabolites in vitro and in vivo.
Targeting Tmprss2, S-protein:Ace2, and 3CLpro for Synergetic Inhibitory Engagement
Authors: Coban Mathew , Morrison Juliet , Freeman William , S. Radisky Evette , Le Roch Karine , Caulfield Thomas
Published: July 2020

We are presenting our on going studies with inhibitory research on Tmprss2, S-protein:Ace2, and 3CLpro using compound screening coupled with X-ray crystallography, molecular modeling, live virus screening using host human cells (BSL3 facility at UC Center for Infectious Disease and Vector Research, and organ-on-a-chip at Harvard Medical School for safety profiling before proceeding to animal models with InVivo BioSystems for ADMET.

We have derived a useful chemical toolkit of 350 compounds for the community to study with biochemical assays and other biophysical-chemical studies that will prove useful in searching for optimal inhibitors of these targets to find suitable pharmacophores for blocking each of these enzyme's activities -- that would be beneficial for human health. Our past successes with these methodologies have resulted in over 28 patents, 11 technologies and two startup companies.
EKSPLORASI KONSTRUKSI BAMBU RECIPROCAL-DEPLOYABLE GRIDSHELL
Authors: Charnele ; Anastasia Maurina Charnele
Published: July 2020

Abstrak - Adanya keterbutuhan akan naungan semi-permanen atau sementara yang mudah dan cepat dibangun untuk sesuatu peristiwa tertentu. Pada penelitian ini menggali potensi struktur bentang lebar transformatif dengan menggabungkan dan mengembangkan sistem struktur konstruksi deployable dan reciprocal dalam bentuk struktur atap bidang gridshell bambu, menjadi sebuah konfigurasi mandiri tersusun dari variasi komposisi modul dengan bantuan komputasional mengikuti kebutuhan desain arsitektur. Hal ini dilakukan dengan mengetahui potensi sistem struktur, pola desain, dan sistem sambungan pada beberapa objek studi yang dievaluasi secara kualitatif dengan metode komparasi pada sistem struktur, sambungan, karakter batang, penyaluran beban, sistem penguncian struktur, dan deployability.Manfaat penelitian berfokus pada penelitian struktur bambu untuk menjadi inovasi baru dalam keteknikan material bambu yang dapat meningkatkan nilai lokalitas Indonesia dengan dapat digunakan masyarakat terutama dalam menggunakan material bambu untuk pengembangan naungan sementara maupun permanen.Pembahasan mengenai kriteria sistem struktur sesuai tujuan penelitian merupakan hasil dari analisa objek studi dimana struktur transformasi berdasarkan karakter struktur deployable sedangkan struktur reciprocal merupakan sistem yang menyokong untuk memberikan kestabilan dan sistem penguncian mandiri. Kedua struktur ini merupakan sistem struktur yang fleksible dan mudah diduplikasi sehingga untuk memenuhi fungsi sebagai struktur bentang lebar, sistem struktur didesain membentuk gridshell. Bentuk gridshell ini yang diolah dengan bantuan komputasional untuk membentuk sistem struktur reciprocal-deployable secara efektif.Penelitian yang bersifat eksplorasi, eksperimen dilakukan pada pola reciprocal hingga menemukan pola paling stabil dan mengubah karakter batang lurus pada reciprocal menjadi batang deployable berupa scissor-like element, lalu mengembangkan jenis sambungan dengan analisa potensi dan kendala tiap sambungan. Eksperimen menghasilkan sistem struktur baru dengan menggabungkan kedua sistem struktur didapatkan struktur yang dapat bertransformasi, memiliki sistem penguncian mandiri, dan dapat membentang lebar dengan bentuk gridshell.
EVALUASI DAN EKSPERIMEN DESAIN MODUL BATA INTERLOCKING UNTUK VARIASI LUAS BUKAAN VENTILASI PADA DINDING
Authors: Budiyani ; Budianastas Prastyatama Ansheila Gabriela
Published: July 2020

Abstrak - Ventilasi alami merupakan desain pasif dalam arsitektur untuk menanggapi negara dengan iklim tropis seperti Indonesia, sehingga dalam perancangan dinding perlu dipertimbangkan material-material bangunan yang dapat menghasilkan bukaan ventilasi. Bata interlocking merupakan salah satu contoh material bangunan dalam arsitektur. Kelebihan dari bata interlocking dibandingkan dengan bata merah yang umum terdapat di pasaran adalah adanya sistem pengunci yang memungkinkan pemasangan bata interlocking lebih efektif, efisien, dan mudah.Pada praktiknya, bata interlocking belum populer digunakan di Indonesia. Untuk menghasilkan dinding yang mempunyai bukaan ventilasi, bata merah yang umum di pasaran lebih diminati daripada bata interlocking. Hal ini dikarenakan desain bata interlocking untuk menghasilkan ventilasi pada dinding masih terbatas dan kurang di eksplorasi. Seringkali sistem pengunci pada bata interlocking membatasi jenis susunan yang dapat digunakan sehingga ventilasi yang dihasilkan juga kurang variatif. Bata interlocking sebenarnya mempunyai potensi untuk menjadi alternatif material untuk menghasilkan ventilasi pada dinding karena sifat-sifatnya yang menyerupai bata merah.Tujuan dari penelitian ini adalah untuk mendapatkan variasi luas bukaan ventilasi yang dihasilkan dari susunan bata dengan cara mengeksplorasi desain bata interlocking melalui eksperimen. Metode yang digunakan adalah metode kualitatif, yaitu dengan mengevaluasi desain preseden bata interlocking dalam kemampuannya menghasilkan bukaan ventilasi yang didasari pada studi literatur. Dari hasil studi literatur dan hasil evaluasi maka dilakukan eksperimen terhadap desain bata interlocking untuk mendapat variasi luas bukaan ventilasi.Hasil eksperimen yaitu desain modul diharapkan bata interlocking dapat menjadi alternatif pilihan material untuk menciptakan bukaan ventilasi pada dinding yang dapat disesuaikan dengan luas ruangan yang ditanggungnya. Oleh karena itu, dinding dari susunan bata interlocking dapat menghasilkan variasi luas bukaan ventilasi yang memenuhi standar yang berlaku sehinggga dapat digunakan pada dinding-dinding yang ingin menghasilkan ventilasi alami.
GREEN PRESCRIPTIONS AND THERAPEUTIC LANDSCAPES: A NEW ZEALAND STUDY
Authors: Marques Bruno , McIntosh Jacqueline , Popoola Tosin
Published: July 2020

No description supplied
Multi-tree Genetic Programming with A New Fitness Function for Melanoma Detection
Authors: Ain Q Ul , Xue Bing , Al-Sahaf Harith , Zhang Mengjie
Published: July 2020

© 2019 IEEE. The occurrence of malignant melanoma had enormously increased since past decades. For accurate detection and classification, not only discriminative features are required but a properly designed model to combine these features effectively is also needed. In this study, the multi-tree representation of genetic programming (GP) has been utilised to effectively combine different types of features and evolve a classification model for the task of melanoma detection. Local binary patterns have been used to extract pixel-level informative features. For incorporating the properties of ABCD (asymmetrical property, border shape, color variation and geometrical characteristics) rule of dermoscopy, various features have been used to include local and global information of the skin lesions. To meet the requirements of the proposed multi-tree GP representation, genetic operators such as crossover and mutation are designed accordingly. Moreover, a new weighted fitness function is designed to evolve better GP individuals having multiple trees influencing each other's performance during the evolution, in order to get overall performance gains. The performance of the new method is checked on two benchmark skin image datasets, and compared with six widely used classification algorithms and the single tree GP method. The experimental results have shown that the proposed method has significantly outperformed all these classification methods.
Taking rejection personally: An ethical analysis of work rejection on Amazon Mechanical Turk
Authors: Johnstone David , Tate M , Fielt E
Published: July 2020

© 26th European Conference on Information Systems: Beyond Digitization - Facets of Socio-Technical Change, ECIS 2018. All Rights Reserved. Amazon Mechanical Turk (AMT) is a popular microtasking platform connecting those who need work done with those willing to do it. However AMT has come under increasing scrutiny for the way workers are treated on its platform. This paper examines one particular component of AMT's microtasking process by conducting a formal ethical analysis, using Tavani's Comprehensive Cyberethics Methodology, on the way work submitted for evaluation is assessed and either accepted or rejected. The study finds that the system is skewed in favour of those evaluating the work, with little recourse for workers, and an apparent disinterest from AMT. This paper contributes to the continuing debate over the governance of, and responsibilities for, those engaged in digital work through such platforms.
Cirurgião-dentista do serviço público na formação de acadêmicos: importância do estágio em serviço
Authors: Rezende Russiane Stefani De Mattos , Oliveira Arlete Maria Gomes , Zanin Luciane , Flório Flavia Martão
Published: July 2020

Estudo observacional transversal para avaliar a percepção do cirurgião-dentista do serviço público sobre a importância do estágio em serviço na formação de acadêmicos de odontologia. Aplicou-se questionário estruturado, autoadministrado e validado a todos os 38 cirurgiões-dentistas que atuavam nas Unidades Básicas de Saúde de Umuarama (Paraná) no ano de 2016. A taxa de resposta foi de 86,8% (33). Todos relataram que o estágio agrega conhecimentos e benefícios aos alunos. Verificou-se que 66,6% (22) dos profissionais não conheciam o significado da preceptoria na Odontologia, em contraponto 69,7% (23) referiram que o preceptor colabora na formação do aluno, contribuindo com a troca de conhecimentos e experiências clínicas. Apenas 3,0% (1) atua como preceptor, 33,3% (11) aceitariam a função e 45,5% (15) não aceitariam devido ao aumento de trabalho e inexistência de incentivo financeiro. Já exerceram a função 27,3% (9), porém se afastaram por falta de comprometimento do aluno, inadequação das UBS, aumento na função de trabalho e falta de incentivo financeiro. Embora reconheçam a importância do estágio, a maioria dos dentistas conhece parcialmente o conceito e responsabilidades da preceptoria e não se sentem incentivados para exercer tal função.