bluuebunny/crossref_metadata_2025 huggingface dataset:
Bacterial Profile of External Ocular Infections, Its Associated Factors, and Antimicrobial Susceptibility Pattern Among Patients Attending Ophthalmology and Optometry Department at Hawassa University Comprehensive Specialized Hospital, Sidama, Ethiopia
Authors: alelign fikir , yeshewaleul kaleb , solomon zekaryias , desta moges
Published: January 2025

Background: External ocular infection(EOI) is a public health problem in developing countries like Ethiopia. EOIs frequently involve the conjunctiva, lid, and cornea of the eye. Bacteria are major causative agents that frequently cause infections in the eyes. Bacterial EOIs is influenced by the virulence of bacteria and by the host's decreased resistance caused by factors including poor personal cleanliness, weakened immune systems, prior eye damage.
Objective: This study aimed to assess the magnitude of bacterial isolates and antibiotic susceptibility profiles of patients with EOIs and identify its associated factors at HUCSH.
Method: A hospital-based cross-sectional study was conducted from May to August 2023 at HUCSH, Sidama Ethiopia. A structured questionnaire was used to collect data related to socio-demographic and clinical characteristics. A total of 376 samples were collected and inoculated on Blood agar, Chocolate agar, and MacConkey agar. Presumptive isolates were further identified by a series of biochemical tests. Antimicrobial susceptibility test was performed for all isolated bacteria according to the criteria of the Clinical and Laboratory Standard Institute by disk diffusion method. Data were analyzed using (SPSS) version 25.0 and bivariate and multivariate logistic regression analysis were used to identify factors associated with external ocular infections. P. value < 0.05 was considered as statistically significance.
Results: A total of 376 patients were enrolled. The overall prevalence of culture-confirmed bacterial external ocular infections was 50.5% (95% CI: 45.4%, 55.7%). Gram-positive bacteria were the most dominant isolate, accounting for 77.9% of cases. The most frequent pathogens isolated were S. aureus (31%) followed by CoNS (23.2%). Antimicrobial susceptibility testing revealed that tobramycin (89.3%) and meropenem (94.1%) were the most effective antibiotics against Gram-positive and Gram-negative bacteria, respectively. Overall, 70% of the isolates were multidrug resistant. Less frequent face washing, systemic disease, and a history of eye surgery were significantly associated with culture-confirmed external ocular infections (EOIs).
Conclusion: The prevalence of bacterial pathogens among external ocular infection was high. Most of the isolates were drug-resistant for commonly used antibiotics. Thus treatment of eye infection in the study site should be guided by drug susceptibility testing of isolates.
Socijalna i etička angažiranost auto-destruktivne umjetnosti
Authors: Metesi Deronjić Željka
Published: January 2025

Daleko od sklada grčkih kipova, renesansne proporcije u kojoj se ogleda metafizička ljepota, jasnoće realizma i spokoja impresionizma, umjetnost 20. stoljeća okreće se novim izražajnim mogućnostima i novim, vrlo često nerazumljivim, možda čak i besmislenim oblicima komunikacije. Jedan od svakako misaono izazovnijih umjetničkih izraza jest auto‑destruktivna umjetnost koja se javlja 60‑ih godina prošlog stoljeća. Tvorac koncepta i autor manifesta auto‑destruktivne umjetnosti Gustav Metzger (1926–2017) svojim je djelom uspješno sjedinio vlastite političke i etičke preokupacije te pokazao veliki stupanj zauzetosti oko aktualnih pitanja društva i njegove (re)humanizacije. Auto‑destruktivni umjetnički izraz ne treba tumačiti kao negaciju slikarstva, već upravo suprotno ‒ kao stvaralački proces koji u sebi nosi snažnu socijalnu i etičku poruku.
Povezanost vršnjačkih odnosa sa školskim angažmanom i uspjehom učenika
Authors: Bilić Vesna
Published: January 2025

Socijalne interakcije temelj su mnogih aktivnosti u suvremenoj školi te se reflektiraju i na školski angažman učenika. Cilj ovog rada je, sistematiziranjem spoznaja iz literature, analizirati kako se odnosi s vršnjacima odražavaju na školski angažman i uspjeh učenika. Kako bismo bolje razumjeli navedeni odnos, uvodno se elaborira uloga nekih individualnih karakteristika učenika i procesa koji doprinose razumijevanju vršnjačkih odnosa i njihove povezanosti sa školskim angažmanom. Analizom rezultata empirijskih istraživanja utvrđeno je da su odnosi s vršnjacima izravno povezani sa školskim angažmanom učenika. Pozitivni, podržavajući odnosi s vršnjacima koreliraju s većim angažmanom učenika u različitim školskim aktivnostima. Suprotno tome, učenici koji imaju negativna iskustva s vršnjacima (neprihvaćanje, odbacivanje ili viktimizaciju) nedovoljno se angažiraju u radu. Školski angažman je medijator koji vršnjačke odnose povezuje s postignućem učenika. Ovaj rad ima važne implikacije za kreiranje pedagoških intervencija usmjerenih na poboljšanje vršnjačkih odnosa, angažmana i uspjeha učenika.
Professional training of teachers for the implementation of teaching about nature and society based on innovative learning and teaching systems
Authors: Živorad M. Milenović Hadži , Vasilijević Danijela N. , Botić Mladen M.
Published: January 2025

The paper examines the need, significance, and methods of professional development for teachers to utilize innovative teaching systems when teaching about nature and society. These systems are equally applicable in teaching other subjects in the lower grades of elementary school and in subject-specific lessons in elementary and high school. The goal of the research is to identify teachers' assessments of their professional development for the realization of teaching about nature and society based on innovative educational systems of learning and teaching. It started from the general assumption that teachers are differently familiar with innovative educational systems of learning and teaching, and therefore do not apply them equally in teaching about nature and society at the level of initial education. It was also based on special assumptions that teachers' familiarity with innovative teaching and learning systems is significantly influenced by their academic education, and that the ways of their professional development are significantly influenced by the level of academic education and teaching experience. In order to determine this, in the December 2023, the research was conducted on a sample of 107 teachers employed in primary schools in the Zlatibor district (Serbia). The data collected have confirmed all research hypotheses. It is concluded that innovative educational systems of learning and teaching are significant in the implementation of teaching about nature and society at the level of initial education, but these are also present among teachers with less than 10 years of experience as well as those with over 30 years of practical experience. To empower teachers in utilizing innovative teaching systems, it is proposed to implement a different professional development approach, which involves a different initial education where they would acquire fundamental knowledge for the use of innovative teaching systems and classroom instruction. Subsequently, they would undergo further professional development through attending training programs on innovative teaching systems.
EFFICACY OF INTRAUTERINE INSEMINATION IN THE MANAGEMENT OF INFERTILITY
Authors:   Junior Resident, Obstetrics and Gynaecology, Varun Arjun Medical College and Rohilkh and Hospital, Shahjahanpur Uttar Pradesh., Nandinikomatineni Nandinikomatineni , Gopal Paul Krishna ,   Professor, Obstetrics and Gynaecology, Varun Arjun Medical College and Rohilkh and Hospital, Shahjahanpur Uttar Pradesh.
Published: January 2025

Introduction: Intrauterine insemination (IUI) aims to enhance the likelihood of conception by directly depositing sperm into the uterine cavity. This abstract assesses the effectiveness of IUI in addressing infertility.

Objectives: To illustrate the efficacy of IUI in addressing infertility. To compare the results of couples who opt for timed intercourse under an identical stimulation protocol with those of couples who select intrauterine insemination (IUI).

Materials And Methods: A descriptive, observational study was conducted in the Department of Gynaecology at VarunArjun Medical College and Rohilkhand Hospital in Shahjahanpur, Uttar Pradesh, India, over duration of 20 months. The research was performed on 50 patients.

Results: In the current study, the majority of individuals, 48%, achieved pregnancy following the IUI cycle.

Conclusion:In light of the scarcity of prospective, controlled studies, managed ovarian hyperstimulation and IUI seem to be at least as cost-effective asIVF when considering the very small direct and indirect costs.
EVALUATION DES TENEURS EN ELEMENTS MINERAUX ET QUALITE DES EAUX SOUTERRAINES DU CONTINENTAL TERMINAL AU SUD-OUEST DU BENIN
Authors:   Chaire Internationale de Physique Mathematique et Applications (CIPMA CHAIRE-UNESCO, UAC)., Jean-Eudes Okounde , Hermionne Adeke ,   Universite dAbomey - Calavi (UAC)., Ringo F. Avahounlin ,   Chaire Internationale de Physique Mathematique et Applications (CIPMA CHAIRE-UNESCO, UAC).,   Laboratoire des Sciences Naturelles et Applications (LSNA, UNSTIM)., Hibe Blaise ,   Universite dAbomey - Calavi (UAC)., Gilbert Danhossou ,   Chaire Internationale de Physique Mathematique et Applications (CIPMA CHAIRE-UNESCO, UAC)., Nelly Kelome ,   Universite dAbomey - Calavi (UAC)., Waris Chouti ,   Universite dAbomey - Calavi (UAC).
Published: January 2025

Agropastoral activities, the main socio-economic activities along Lake Toho, are not without effects on the quality of soil and water. The objective of this study is to evaluate the degree of transfer of chemical elements and the quality of groundwater from the continental terminal to the southwest of Benin. Thus, along Lake Toho, nineteen large diameter wells and boreholes were sampled and the physicochemical parameters were measured using appropriate analysis methods. The calculation of different empirical indices made it possible to assess the quality and potability of groundwater. The determination of physicochemical parameters showed that the contents of chemical elements contained in the groundwater comply with Beninese standards and those prescribed by the WHO except for temperature, magnesium and chlorides, the values of which were obtained at the wells. Itehoue and Condji Agname are extraordinary. The index values showed that the quality of groundwater is good in 12 localities and of excellent quality (Kpocondji Yosso) in some places. The overall assessment of quality reveals that the water quality is good almost everywhere and excellent in Tohonou Dadahoue in Hahame Agbodougbe average in Itehoue and Bota and very bad in Goudon.
Carbon dioxide emissions, forest area, and economic growth of SAARC countries: Evidence from FMOLS approach
Authors: Mani Upadhyaya Yadav , Raj Kharel Khom , Poudel Omkar , Nepal Pramshu
Published: January 2025

This study aims to examine the relationship between CO2 emissions, forest area, and GDP in each South Asian Association for Regional Cooperation (SAARC) country. This study uses a panel dataset that spans South Asian countries from 1990 to 2020 for econometric analysis. The Fully Modified Least Squares (FMOLS) method adds annual forested area to the regression model. The study results show that India, Nepal, Pakistan, and Sri Lanka must prioritize decoupling CO2 emissions from economic growth, as their strong correlation shows significant environmental costs of development. Although Bangladesh, Bhutan, and the Maldives are in a slightly better position, they need strategies to manage emissions as they progress economically. The study once again revealed a relationship between a 1% increase in GDP and a 0.68% rise in CO2 emissions, whereas a 1% increase in forest area led to a slightly higher 0.79% rise in CO2 over the period. The hypotheses testing results confirm a positive correlation between economic growth and carbon dioxide emissions in SAARC countries, indicating that emissions rise as economies expand. Additionally, a negative relationship was found between forest area and carbon dioxide emissions, where larger forest coverage is linked to lower emissions. The conclusion is that an increase in forest area is associated with a relatively small increase in CO2 emissions, indicating that the relationship between forest area and CO2 emissions is less pronounced compared to GDP.
One-Pot Sodium Azide-Free Synthesis of Aryl Azides from Anilines
Authors: G. C. de Moraes Leonardo , B. Guidinele Maria Cristina , F. Ferreira Vitor , R. da Rocha David
Published: January 2025

This work presents an easy and efficient one-pot protocol for the synthesis of aryl azides without
using sodium azide or hydrazine hydrate starting from anilines via aryl hydrazines. This protocol
can be applied to anilines bearing groups with donating or withdrawal electronic characteristics.
(IN)SEGURANÇA ALIMENTAR E NUTRICIONAL DE ADULTOS ATENDIDOS PELO PROGRAMA BOLSA FAMÍLIA NO MUNICÍPIO DE PINHALZINHO (SC)
Authors: Bamberg Gustavo Luiz , Da Silva Tairine , Lutinski Junir Antonio
Published: January 2025

O Programa Bolsa Família (PBF) foi criado com intuito de melhorar a condição de vida de pessoas com baixa renda, funcionando como um complemento à renda familiar. O presente estudo objetivou avaliar o impacto do PBF na promoção ou garantia da Segurança Alimentar e Nutricional (SAN) de beneficiários no município de Pinhalzinho (SC). Participaram do estudo 32 titulares beneficiários. Foram aplicados questionários para identificar o perfil socioeconômico, frequência alimentar e Escala Brasileira de Insegurança Alimentar (EBIA). Apenas 12,5% dos participantes da pesquisa encontram-se em segurança alimentar. Percebeu-se a prevalência de obesidade grau I em 34,4% dos participantes e sobrepeso em 28,1%. Os resultados enaltecem a importância da adoção de políticas intersetoriais, em paralelo ao Programa Bolsa Família, para o fortalecimento de práticas alimentares saudáveis.
IMPACTO SOCIAL E ECONÓMICO DO REASSENTAMENTO NO DISTRITO DE CHIBUTO, GAZA/MOÇAMBIQUE: CASO DAS FAMÍLIAS DE NWAHAMUZA AFECTADAS PELA EXPLORAÇÃO DAS AREIAS PESADAS DE CHIBUTO
Authors: Rosário Nelson Maria , Candido Nelio Mariano , Macie Dorciana Américo
Published: January 2025

O presente artigo analisou o impacto socioeconómico do reassentamento causado pela exploração das areias pesadas de Chibuto nas famílias de Nwahamuza no período de 2017 a 2021. Para o alcance dos objetivos traçados pela pesquisa, este estudo suportou-se na abordagem quantitativa e qualitativa, onde constituíram objetos da pesquisa 30 famílias reassentadas, sendo a entrevista, questionário e a observação sistemática como os principais instrumentos usados para a recolha de dados. Os resultados da presente pesquisa mostraram aspectos posetivos de realce, como o caso do acesso que a população reassentada passou a ter a água potável, saúde, energia e habitação e em contrapartida, houve deterioração no nível de identidade cultural da população, bem como das suas estratégias de sobrevivência, o que se reflecte agora no empobrecimento de algumas famílias e no sentimento que a mesma tem, em viver como hóspede no local reassentamento.
Palavras-chave: Reassentamento populacional, integração e impacto socioeconómico.
AVALIANDO AS PROPOSIÇÕES DE RESTAURAÇÃO DE UNIDADES DE CONSERVAÇÃO DA MATA ATLÂNTICA NO ESTADO DE SÃO PAULO*
Authors: Borges Tiago , Gallo Humberto , Massi Klécia , Bignotto Rafael , Freitas Miguel
Published: January 2025

O estabelecimento de Unidades de Conservação (UC) tem sido uma das estratégias para minimizar a intensa pressão antrópica sobre a Mata Atlântica. No entanto, as UC também possuem em seu interior porções de áreas que necessitam de ações de recuperação ou restauração de ecossistemas degradados. Os Planos de Manejo destas áreas protegidas devem conter programas de recuperação com diretrizes das ações a serem implantadas. O presente trabalho objetivou avaliar as diretrizes e ações de recuperação propostas nos Planos de Manejo de Unidades de Conservação da Mata Atlântica no Estado de São Paulo, Brasil. Foram analisados os Planos de Manejo de 20 Parques Estaduais e cinco Áreas de Proteção Ambiental (APAs), elencando-se e avaliando-se as ações de recuperação previstas
PROPOSTA DE IMPLANTAÇÃO DE TÉCNICA SUSTENTÁVEL PARA MANEJO DE ÁGUAS PLUVIAIS URBANAS EM PONTO CRÍTICO DE ALAGAMENTO DO MUNICÍPIO DE JABOATÃO DOS GUARARAPES/PE
Authors: Pessoa Neto Amaury Gouveia , Silva Evele Mayara Barros da , Silva Luciana Cássia Lima da , Silva Simone Rosa da , Lafayette Kalinny Patrícia Vaz
Published: January 2025

O presente estudo buscou identificar as classes de uso e ocupação do solo de uma área de adensamento urbano do município de Jaboatão dos Guararapes - PE, bem como propor a implantação de jardins de chuva como técnica compensatória nessa região, a fim de mitigar a ocorrência de episódios de alagamentos. Para isso, foi delimitada uma bacia de contribuição como área de estudo, a partir de um ponto crítico de alagamento localizado na Estrada da Batalha, a qual foi submetida a uma análise visual fotointerpretativa, baseada em ortoimagens com escala de 1:1.000, que permitiu demonstrar que a áreas impermeabilizadas prevalecem no local, representando 73,43% da região em estudo. Foi considerada a instalação dos jardins de chuva no canteiro central da via e em parte de seu passeio, os quais foram dimensionados com larguras de 6,00 m e 7,50 m e comprimentos de 110,00 m e 70,00 m, respectivamente, sendo capazes de armazenar 245,10 m³ e 287,44 m³ das águas precipitadas. A partir dos resultados obtidos, destaca-se a eficiência dessa técnica compensatória na contribuição para mitigação de episódios de alagamento em ambientes urbanos.
DO RIO A RODOVIA: AS FORMAS ESPACIAIS DE SILVES E ITAPIRANGA
Authors: Da Silva dos Santos Rayssa , Bernardino Araújo da Silva Fredson , Oliveira Neto Thiago
Published: January 2025

O presente artigo aborda as principais mudanças espaciais que ocorreram nas cidades de Silves e de Itapiranga na complexidade da rede urbana regional, como a abertura das rodovias estaduais e o adensamento de objetos técnicos no território. Partiu-se de abordagem descritivo-analítica, com trabalho de campo (27-29 de agosto de 2022) no percurso entre Manaus, Itapiranga e Silves, nas rodovias AM-010, AM-330 e AM-363, que estão centralizadas no berço da extração do gás natural, dinâmica que tem alterado o território, as populações locais que passam a se distribuir a favor da rodovia e ter maior relações com os eixos rodoviários. Sobretudo em Itapiranga, há uma dinâmica de transição de uma cidade ribeirinha para uma cidade rodoviária. Destacou-se o turismo religioso como prática “tradicional” relacionada com novos elementos de modernização.
CARACTERIZACIÓN FISICOQUÍMICA Y MICROBIOLÓGICA DE LODOS DE PTAR Y BES BAJO UN ENFOQUE DE REAPROVECHAMIENTO AGRONÓMICO
Authors: Candela Levano Gianella M. , Miglio Toledo Rosa , Vela Cardich Rosemary , Cadillo La Torre Erika A.
Published: January 2025

The objective of the study was to evaluate the agronomic potential of WWTP and DT sludge produced in Peru. For this, different aerobic and anaerobic wastewater treatment technologies were selected, as well as on-site sanitation systems in the cities of Lima, Ayacucho, Arequipa and Cusco. The aerobic technologies evaluated were: conventional aeration activated sludge, extended aeration, ICEAS and aerated lagoon. Regarding the anaerobic technologies, the following were selected: anaerobic lagoon, anaerobic digester and Imhoff tank. The on-site sanitation systems chosen were those with weekly, monthly and annual storage chambers. The sampled sludge was characterized physicochemically and microbiologically according to DS-N°015-2017-VIVIENDA, which determines whether a sludge can be reused and classified as type A or B biosolids. Type A biosolids are applicable to the soil without sanitary restrictions. while those of type B have restrictions depending on the location of the soil and/or type of crop. The concentrations of C, N, P and K in the sludge were analyzed to evaluate their possible agronomic reuse. It was found that extended aeration sludge, aerated lagoon, anaerobic lagoon, anaerobic digester and Imhoff tank have characteristics similar to those of type B biosolids and have adequate agronomic potential due to their content of organic matter and nutrients. On the other hand, conventional aeration sludge, ICEAS and BES require stabilization processes to be reused.
ELABORACIÓN DEL BIOPRODUCTO “ALPA-BIOL” EN CONDICIONES ALTO ANDINAS
Authors: Quiñones Ramírez Henrry , Carrión-Carrera Gladys , Juscamaita Morales Juan
Published: January 2025

Alpa-biol es un bioproducto desarrollado por el Departamento de Biología de la Universidad Nacional Agraria La Molina vía fermentación homoláctica a partir de heces de alpaca en condiciones de laboratorio, cuyo proceso de elaboración podría verse afectado por factores ambientales adversos. El objetivo del estudio fue evaluar la eficiencia de la fermentación homoláctica en condiciones alto andinas, replicando la elaboración del Alpa-biol a mediana escala en la Sociedad Agrícola de Interés Social (SAIS) Pachacútec (Junín). Para ello se emplearon heces de alpaca, lactosuero, melaza y el consorcio microbiano benéfico “B-Lac” en proporción 40:40:15:5, respectivamente, monitoreándose diariamente el pH hasta alcanzar el valor más bajo. Se realizaron análisis físico[1]químicos y microbiológicos al inicio y después de 1 año a fin de determinar su estabilidad en el tiempo. Los resultados fueron comparados con los parámetros del Alpa-biol original, con 2 grupos de biofermentos (abonos líquidos acelerados y bioles de digestión anaerobia) y estándares de calidad. Se obtuvo en un periodo corto de 10 días un bioproducto carente de enteropatógenos, con caracteres organolépticos deseables, adecuado contenido nutricional y estable en el tiempo, similar a los reportes del estudio original y al grupo de abonos acelerados. Sin embargo, existen diferencias notables con respecto a los bioles debido a la naturaleza fermentativa, siendo su uso indicado en sistemas de producción agrícola como bioenmienda.
Raíces históricas de cuerdas separadas de la agronomía y los marginados conocimientos originarios en las universidades de Cusco y Ayacucho
Authors: Calderón Mendoza Constantino
Published: January 2025

This article explores the history of the agronomy faculties, created in the late 1950s at the Universidad Nacional de San Antonio Abad del Cusco (UNSAAC) and the Universidad Nacional de San Cristóbal de Huamanga in Ayacucho (UNSCH), from a contextual perspective.  These institutions are important as part of the policy of state control; for this reason, their foundation dates back to the early colonial period. By examining their historical origins, this study seeks to understand the absence of bilingual intercultural agronomic training in the curricular content in these two regions with a majority rural indigenous Quechua-speaking population. This article begins by referencing coloniality in higher education; then describes the context of the creation of the agronomy degree. It then specifies the history of the Faculty of Agronomy of the Universidad Nacional de San Antonio Abad del Cusco (UNSAAC), followed by the Faculty of Agronomy of the Universidad Nacional de San Cristóbal de Huamanga (UNSCH). From this analysis, it becomes evident that the state’s higher education policy has historically excluded the original knowledge of agriculture and its epistemic worldview in the training of agronomists. The original knowledge has been made invisible by centralist political discourses from Lima, which label it as backward, inferior, unscientific, among other things. However, paradoxically, at present, more than 70% of the national demand for food is produced with the original knowledge practiced by family farming. The article concludes with some preliminary conclusions leading to the understanding of the absence of bilingual intercultural training, which would logically be expected in these regions of high density of Andean peasant agriculture and Quechua speakers. The lack of inclusion of bilingual intercultural agronomic higher education is due to state policy defined in the national constitution, the congress of the republic and the executive government. We believe that behind it, there is something deeper of a historical nature: the form of naturalized colonial mindset.
Use of Three-dimensional Printed Carpal Bones for Various Carpal Pathologies: A Systematic Review
Authors: Seth Ishith , Bulloch Gabriella , Seth Nimish , Fogg Quentin , Hunter-Smith David J. , Rozen Warren M.
Published: January 2025

Background:

Three-dimensional (3D) printing technology allows for patient-specific anatomical reconstruction. This study aims to summarize and critique the current literature on 3D-printed carpal bone implants used in various carpal pathologies.

Methods:

Web of Science, PubMed, Scopus, Google Scholar, and Cochrane Central Register of Controlled Trials databases were searched from January 1901 to October 2022. PRISMA guidelines were adhered to, and the study was registered on PROSPERO. Articles utilizing 3D printed carpal bone implants were selected based on pre-determined inclusion and exclusion criteria. The outcomes included intraoperative/postoperative complications, visual analogue score (VAS), disabilities of the arm, shoulder and hand (DASH) score, radial and ulna deviation. The Murad tool was used to assess the quality of case reports and Newcastle Ottawa scale was used to assess the observational studies.

Results:

A total of 6 studies comprising of 47 patients (34 males) were included. The average age was 35.3 years and indications for 3D printed implants included Fenton syndrome, Kienböck’s disease, and scaphoid non-union with and without necrosis. The overall postoperative VAS ranged from 0 to 1.4 and a significant reduction was noted from preoperatively with both rest and loading. The overall postoperative DASH score ranged from 9.2 to 25 and significant improvement was noted from preoperatively. The radial deviation ranged from 16.4° to 28.5° and while ulna deviation was from 23.8° to 36.4°. Only one complication was reported in included studies, a dislocation of the prosthesis. The overall quality of included studies was poor.

Conclusion:

3D-printed carpal bone implants improved outcomes in pain and function with minimal complications. The current study only reported only one complication postoperatively with no intraoperative complications. These results suggest that while 3D-printed carpal bone implants are still being optimized, large-scale clinical studies comparing the current options with the standard of care would provide better insights for recommendations and counseling.
Hindquarter Amputation as a Successful Treatment of Chronic Pain in an Adolescent with PTEN Hamartoma Tumor Syndrome
Authors: Taverner Fiona J , Wylie Nicole E , Farmer Lachlan DM , Barnett Christopher P , Yeung Ping HJ , Burgoyne Laura L
Published: January 2025

Background:

The PTEN hamartoma tumor syndrome comprises a group of rare conditions caused by germline mutations of the tumor suppressor gene PTEN (Phosphatase and TENsin homolog deleted on chromosome 10). They include Cowden syndrome, Lhermitte-Duclos disease, and Bannayan–Riley–Ruvalcaba syndrome, but it appears likely that these conditions represent the spectrum of PTEN hamartoma tumor syndrome, in which penetrance and clinical variability play significant roles. The clinical features of PTEN hamartoma tumor syndrome vary between individuals and can appear at any age. They include an increased risk for certain types of cancers and benign tumors, as well as tumor-like malformations (hamartomas) and neurodevelopmental disorders.

Case Presentation:

We report the case of an adolescent male with PTEN hamartoma tumor syndrome who developed severe chronic pain in the context of multiple arteriovenous malformations of the left lower limb. He successfully underwent hindquarter amputation to manage a nonhealing ulcer, recurrent episodes of life-threatening hemorrhage, and escalating analgesic requirements. He had a remarkable recovery with neither pain nor phantom sensory issues and significant improvement in his quality of life.

Conclusion:

Despite chronic preoperative pain, the radical surgery in this patient with PTEN hamartoma tumor syndrome resulted in an improved quality of life and virtually no long-term pain or analgesia requirements.
Leaflet Lebih Efektif Meningkatkan Pemahaman Penggunaan Pil Kontrasepsi Hormonal Kombinasi Dibandingkan Dengan Video Edukasi Pada Akseptor KB di Puskesmas Bareng Kota Malang
Authors:   S1 Kebidanan Universitas Brawijaya, Rahmana Rahima Azzahra , Norahmawati Eviana ,   Departemen Patologi Anatomi Fakultas Kedokteran Universitas Brawijaya, Wati Linda Ratna ,   Departemen Kebidanan Fakultas Kedokteran Universitas Brawijaya
Published: January 2025

Background: Based on Badan Pusat Statistik Data (2022) total acceptors of hormonal contraceptive pills in Malang is up to 14.580 women. Hormonal contraceptive pills are a contraceptive method that has to be consumed per-oral daily to give an effective result. Hormonal contraceptive usage could increase estrogen exposure to acceptors’ body, this exposure on the long term (usage > 3 years) could increase the risk of breast cancer. Knowing this risk, it is exceedingly needed for the acceptors to be given an education about how to use the hormonal contraceptive pills correctly. Leaflets and educational videos are proven to be effective to increase someone’s knowledge quiet well. Aim: to determine the difference in effectiveness between educational leaflets and videos on the understanding level of the use of combined hormonal contraceptive pills among family planning acceptors at Puskesmas Bareng Malang City. Method: an experimental research using comparison group design using Wilcoxon Matched Pairs Test. Result: After being provided with educational leaflets, there was an increase in understanding. The significance value obtained was p < 0.001 < α = 0.05. Similarly, using educational videos yielded the same value of p < 0.001 < α = 0.05. The Wilcoxon Signed Rank Test value indicates that there are 12 respondent values from the educational video group that are lower than the values of the leaflet group, with a mean rank of 10.54 and a sum of ranks of 126.50. The Asymp. Sig. (2-tailed) is 0.017 < 0.05, suggesting a significant difference in the effectiveness of education delivery between leaflets and educational videos. The use of leaflet educational media is more effective than educational videos. Conclusion: giving health education while using leaflet and educational video as the media is proven to significantly increase someone’s knowledge, with leaflet is slightly more significant to increase someone’s knowledge.
Peran ASEAN Outlook on Indo-Pacific (AOIP) dalam Mengukuhkan Indonesia sebagai Poros Maritim Dunia
Authors: Handika Juan , Amini Tasya , Michelle Josephine
Published: January 2025

Dunia mengenal Indonesia sebagai negara maritim, maka tak heran jika Indonesia memiliki visi sebagai poros maritim dunia. Dalam mewujudkan hal ini, tentu Indonesia memerlukan kebijakan luar negeri yang tepat sebagai suatu strategi dengan disesuaikan kepentingan nasional yang dimiliki. ASEAN Outlook on Indo-Pacific (AOIP) dianggap tepat untuk diadopsi Indonesia sebagai upaya dalam mewujudkan hal tersebut. Penelitian ini ditujukan guna mengalisis lebih lanjut bagaimana AOIP bertransformasi menjadi salah satu strategi Indonesia dalam upaya mencapai visi poros maritim dunia. Tulisan ini didukung dengan metode penelitian kualitatif melalui pendekatan studi literatur dalam upaya memperkuat analisis topik penelitian. Penggunaan teori realisme dan konsep kebijakan luar negeri turut dipilih sebagai kerangka pemikiran dalam mengkaji lebih lanjut topik ini. Analisis dalam penelitian ini menunjukkan bahwa AOIP merupakan strategi yang tepat dalam membantu kepentingan nasional Indonesia yang berkaitan dengan visi poros maritim dunia, dengan AOIP menyokong aspek ekonomi dan pembangungan, mempertahankan kedaulatan, serta menjaga stabilitas dan kerja sama kawasan
Kemitraan Strategis Perdagangan Indonesia-Amerika Serikat: Menavigasi Tantangan Global dan Potensi Keunggulan Kompetitif
Authors: Qoni'ah Risa
Published: January 2025

Indonesia dan Amerika Serikat (AS) telah menjalin hubungan diplomatik sejak tahun 1949, dan kedua negara sepakat untuk memperkuat kerja sama melalui Kemitraan Komprehensif yang dimulai pada tahun 2010. Menindaklanjuti keberhasilan tersebut, kedua negara meningkatkan hubungan Indonesia-AS melalui Kemitraan Strategis untuk memperluas kerja sama yang terkait dengan isu-isu regional dan global. Bagi Indonesia, Amerika Serikat merupakan salah satu mitra dagang utama perekonomian Indonesia. Indonesia telah mengalami surplus neraca perdagangan dengan AS selama kurun waktu 5 tahun terakhir. Namun demikian, masih terdapat berbagai risiko yang dapat menghambat perdagangan global seperti ketegangan geopolitik, melemahnya permintaan global, dan perubahan iklim. Oleh karena itu, penelitian ini bertujuan untuk mengkaji peluang dan tantangan kerja sama ekonomi Indonesia dan AS di tengah permasalahan perdagangan global. Penelitian ini dilakukan dengan metode kualitatif yang mengumpulkan informasi yang relevan dari buku, artikel jurnal, dan publikasi pemerintah. Hasil peneltian menunjukkan bahwa tantangan kerja sama perdagangan antara Indonesia dan AS antara lain kondisi makro ekonomi Amerika Serikat yang mempengaruhi permintaan atas produk Indonesia, meningkatnya peluang proteksionisme yang lebih mengutamakan industri dalam negerinya, tertundanya pemberian fasilitas Generalized System of Preference (GSP), dan adanya kebijakan Inflation Reduction Act (IRA). Namun, Indonesia mempunyai peluang yaitu masih terbukanya peluang untuk peningkatan pangsa pasar, perang dagang antara Tiongkok dan Amerika Serikat menjadi peluang adanya perpindahan market demand atas produk Indonesia dan keikutsertaan Indonesia dalam IPEF diharapkan dapat meningkatkan akses pasar ke Amerika Serikat.
Conflict and Media Framing: The Case of Detik.com News towards Rohingya Conflict
Authors: Afandi Ahmad Ali , Isyroqun Hammad , Sholeh Badrus
Published: January 2025

This study analyzes the framing strategies used by Detik.com in covering the Rohingya conflict using the Robert N. Entman approach. Through an analysis of a number of published news, it was found that Detik.com tend to portray the crackdown by the Myanmar government as a violation of human rights and international law. The reports highlighted the systematic violence and persecution experienced by the Rohingya community, describing it as a form of oppression perpetrated by the Myanmar regime against the Muslim minority. This framing positions the Rohingya community as victims and exposes Myanmar as the main perpetrator of international human rights violations. Detik.com framing strategy not only focuses on describing events, but also emphasizes the violent relationship between the Myanmar government and the Rohingya community as an issue that requires international attention. Through reports that emphasize the need for international intervention and protection for the Rohingya community, Detik.com directed its audience to condemn the actions of the Myanmar regime and support solutions oriented towards the protection of the rights of the Rohingya community. In addition, Detik.com also showed the solutions offered, which are more likely to favor independence and the return of Rohingya refugees to Myanmar in safe conditions. Using Robert N. Entman's framing theory, the study reveals how Detik.com frame the Rohingya conflict as an issue related to human rights, international law, and the need for international intervention to protect victims. This framing not only exposes the reality of the violence experienced by the Rohingya, but also illustrates the need for global action to ensure long-term protection for the Rohingya community who continue to live in insecurity.
The Trifecta of Industry, Academic, and Health System Partnership to Improve Mental Health Care Through Smartphone-Based Remote Patient Monitoring: Development and Usability Study
Authors: Epperson C Neill , Davis Rachel , Dempsey Allison , Haller Heinrich C , Kupfer David J , Love Tiffany , Villarreal Pamela M , Matthews Mark , Moore Susan L , Muller Kimberly , Schneck Christopher D , Scott Jessica L , Zane Richard D , Frank Ellen
Published: January 2025

Background

Mental health treatment is hindered by the limited number of mental health care providers and the infrequency of care. Digital mental health technology can help supplement treatment by remotely monitoring patient symptoms and predicting mental health crises in between clinical visits. However, the feasibility of digital mental health technologies has not yet been sufficiently explored. Rhythms, from the company Health Rhythms, is a smartphone platform that uses passively acquired smartphone data with artificial intelligence and predictive analytics to alert patients and providers to an emerging mental health crisis.

Objective

The objective of this study was to test the feasibility and acceptability of Rhythms among patients attending an academic psychiatric outpatient clinic.

Methods

Our group embedded Rhythms into the electronic health record of a large health system. Patients with a diagnosis of major depressive disorder, bipolar disorder, or other mood disorder were contacted online and enrolled for a 6-week trial of Rhythms. Participants provided data by completing electronic surveys as well as by active and passive use of Rhythms. Emergent and urgent alerts were monitored and managed according to passively collected data and patient self-ratings. A purposively sampled group of participants also participated in qualitative interviews about their experience with Rhythms at the end of the study.

Results

Of the 104 participants, 89 (85.6%) completed 6 weeks of monitoring. The majority of the participants were women (72/104, 69.2%), White (84/104, 80.8%), and non-Hispanic (100/104, 96.2%) and had a diagnosis of major depressive disorder (71/104, 68.3%). Two emergent alerts and 19 urgent alerts were received and managed according to protocol over 16 weeks. More than two-thirds (63/87, 72%) of those participating continued to use Rhythms after study completion. Comments from participants indicated appreciation for greater self-awareness and provider connection, while providers reported that Rhythms provided a more nuanced understanding of patient experience between clinical visits.

Conclusions

Rhythms is a user-friendly, electronic health record–adaptable, smartphone-based tool that provides patients and providers with a greater understanding of patient mental health status. Integration of Rhythms into health systems has the potential to facilitate mental health care and improve the experience of both patients and providers.
Exploring the Acceptance and Opportunities of Using a Specific Generative AI Chatbot to Assist Families in Managing Paediatric Rheumatological Chronic Health Conditions: A Mixed-Methods Study (Preprint)
Authors: Lau Cheryl , Kupiec Klaudia , Livermore Polly
Published: January 2025

BACKGROUND

Healthcare chatbots can be used to support patients with everyday decision-making. While there is some research on integrating artificial intelligence (AI) into paediatric care, no study has focused on the opportunity of implementing a generative AI (genAI) chatbot for paediatric rheumatology. Paediatric Rheumatology conditions require intense family input, which can often leave families struggling to navigate disease flares, pain, fatigue, medication side effects and adherence and support of their child, often when paediatric rheumatology departments are shut. Understanding how we can support families better, without the need for increased personnel, will have implications for the healthcare systems.

OBJECTIVE

The study aimed to explore children and young peoples (CYP) and parental acceptance of chatbot use in a paediatric context and understand how a chatbot can be specifically utilised for managing a child’s chronic health condition.

METHODS

This study was a mixed-methods design, utilising both a family workshop and subsequent questionnaire.

RESULTS

In total, 22 participants contributed to the table at the world care methodology workshop and 47 participants (36 parents and 11 children and young people) completed the questionnaire. Participants expressed their likelihood of using chatbot technology, including ChatGPT, due to its accessibility. However, participants had significantly greater intention (CYP: p=.006; Parents: p <.001) to use a specific chatbot over ChatGPT, due to increased trust, credibility, and specificity in design. CYP and parents should be distinguished as two user groups in chatbot design, reflecting their specific needs in chatbot features and personalisation.

CONCLUSIONS

Overall, the study reinforced the need for a specialised and trusted chatbot designed with input from health professionals to assist families in managing complex chronic health conditions. Future research should evaluate users’ engagement with a functional prototype to investigate its usefulness and explore its implementation into families’ everyday life. Importantly, the current findings have broader implications for the field of paediatric healthcare, as similarly tailored chatbot interventions could benefit families who are managing other chronic health conditions.
COMPUTATIONAL STUDY OF FREQUENCY IMPACT ONTO THE PARTICLE PARAMETERS AND CHANGE IN ACOUSTIC AGGLOMERATION TIME WITH THE NUMBER OF PARTICLES
Authors: Rayapureddy Sai Manoj , Maknickas Algirdas , Matijošius Jonas , Vainorius Darius , Kilikevičius Artūras
Published: January 2025

Air pollution, especially from particulate matter (PM), is a significant environmental and health issue worldwide. This research examines the use of acoustic agglomeration (AA) as a novel technique to diminish fine particle emissions, concentrating on the influence of frequency on particle characteristics and agglomeration duration. This study aims to improve the effectiveness of traditional filtration systems by investigating acoustic wave-induced particle agglomeration as an alternative method. The research integrates experimental and computational methodologies. Emissions from a 1.9 turbocharged 4-cylinder diesel engine using FAT80IP20 fuel were subjected to analysis in a custom-designed acoustic chamber. Frequencies of 21.2 kHz and 34.6 kHz were used, with particle measurements recorded using a Fluke 985 particle counter. Computational simulations using the Discrete Element Method (DEM) were performed to examine particle behaviour at different acoustic frequencies, accounting for first-order factors such orthokinetic interactions and acoustic wake effects. Results demonstrate that elevated frequencies (34.6 kHz) accelerate particle agglomeration, although the overall quantity of agglomerated particles diminishes. Experimental results indicated a 62.78% decrease in 5 μm particles and a 300% rise in 10 μm particles at 34.6 kHz. The findings correspond with the computer calculations, which indicated that heightened frequency enhances particle mobility and collisions while diminishing the likelihood of prolonged agglomeration inside the chamber confines. The results confirm the efficacy of acoustic agglomeration for emission control, emphasising a frequency-dependent trade-off between agglomeration speed and the volume of agglomerated particles. This study advances the development of sophisticated filtering technologies and more environmentally friendly transportation alternatives.
EVIDENCIA DE COMPORTAMIENTO REPRODUCTIVO DE TORTUGA VERDE DEL PACÍFICO ORIENTAL (Chelonia mydas) EN EL PARQUE NACIONAL ARCHIPIÉLAGO DE REVILLAGIGEDO, MÉXICO
Authors: Hernández Burgos Fernando Ivan , Fernández-Sanz Helena , Flores-Gasca Laura Andrea , Resendiz Eduardo
Published: January 2025

La tortuga verde del Pacífico Oriental (Chelonia mydas) localmente conocida como tortuga prieta o negra, es una especie catalogada en peligro de extinción.  A través de los monitoreos e investigación de tortugas marinas en el Archipiélago de Revillagigedo para la elaboración de la línea base de información sobre la anidación y evaluación de salud de tortugas negras en la región, se obtuvieron los primeros registros fotográficos de cópula en Bahía Azufre en Isla Clarión y en Bahía Vargas Lozano en Isla Socorro, durante la temporada pico de anidación, lo que indica una temporada reproductiva extendida.
APROXIMACIONES GENÓMICAS Y SU UTILIDAD EN LA IDENTIFICACIÓN DE GENES INVOLUCRADOS EN ADAPTACIÓN LOCAL EN ECTOTERMOS, CON ÉNFASIS EN HERPETOFAUNA
Authors: Pastenes Luis , Salazar-Viedma Marcela , Zúñiga Alejandro , Fuentealba Marta
Published: January 2025

La heterogeneidad ambiental es un factor determinante en la evolución de la plasticidad fenotípica de los organismos. Los ambientes marcadamente heterogéneos son escenarios ideales para investigar los procesos y mecanismos de adaptación. Para diversos taxa, existe un importante cúmulo de evidencia sobre la influencia de la variación geográfica en los rasgos morfológicos, conductuales y de historia de vida. Sin embargo, pocos estudios han examinado las bases genéticas de esta variación, y más escasos aún aquellos que han indagado en los patrones de expresión genética asociados a la adaptación. Esos estudios, mayoritariamente relacionan la existencia de variación geográfica con genes candidatos a selección direccional. El objetivo de este trabajo es documentar las aproximaciones genómicas existentes para la identificación de genes asociados al proceso de adaptación local en ectotermos, evidenciando su potencial uso en la búsqueda de genes candidatos para el estudio de los mecanismos adaptativos en herpetozoos.
NUEVOS REGISTROS Y ESTADO ACTUAL DE Boana picturata (HYLIDAE) PARA EL DEPARTAMENTO DEL CHOCÓ, COLOMBIA
Authors: Rivas Albornoz Lucellis , Rengifo Mosquera Jhon Tailor , Palacios Rodrigez Lizeth Johana , Rengifo Palacios Mayra Yulenis
Published: January 2025

Boana picturata es una rana arborícola de hábitos nocturnos, que presenta problemas de hábitats producto de actividades antropogénicas que ponen en riesgo sus poblaciones, por lo tanto, conocer el área de distribución de esta especie es fundamental para la elaboración de planes de conservación de la misma. Por lo tanto, en esta investigación se documentan nuevas localidades de B. picturata para el departamento del Chocó. Los individuos fueron registrados en las localidades de Angostura (Municipio de Tadó) en el Afirmado (Municipio Alto Baudó), Salero (Municipio de Unión Panamericana) y Tribugá (Municipio Nuquí), esta última localidad resultado de la Expedición Biológica, Serranía del Baudó.
ACTUALIZACIÓN DE LA RIQUEZA HERPETOFAUNÍSTICA DEL MUNICIPIO DE ZAPOTITLÁN DE MÉNDEZ, PUEBLA, MÉXICO
Authors: Díaz García Juan Manuel , Juárez Ramírez Maria Chanel , Diaz Felix Alan Emir , Sánchez-Ochoa Daniel Joaquín , Pacheco-Méndez Perla Isabel , Hernández-Bautista Abigail Paola , Kelly-Hernández Alfonso , Lucas-Juárez Gaudencio , Hernández-Juárez Marcelino
Published: January 2025

A través de trabajo de campo, revisión de ejemplares en colecciones científicas y una campaña de ciencia ciudadana, presentamos nuevos registros de anfibios y reptiles del municipio de Zapotitlán de Méndez, Puebla. Asimismo, aportamos información sobre la ampliación del área de distribución para algunas especies registradas. La herpetofauna del municipio comprende 43 especies,  distribuidas en 11 especies de anfibios (9 Anura, 2 Caudata) y 32 especies de reptiles (31 Squamata, 1 Testudines). El mayor número de especies reportadas fue en la cabecera municipal que recibe el mismo nombre del municipio, seguido por la localidad de Tuxtla, y finalmente por la localidad de Nanacatlán.