bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of regulatory impact on ensuring sustainable development and functioning of housing and communal services
Authors:   Moscow Analytical Center in the field of urban economy, Balashov E.B.
Published: June 2023

In modern conditions, it is becoming urgent to search for a new model for assessing various types of impact (adopted normative legal acts, national goals, programs and projects) on the development of various sectors of the economy. The article discusses the features of methodological approaches and the developed model for assessing the economic impact of the implementation of programs to improve the state of housing and communal services (housing and communal services). The main directions of the development of the institute for regulatory impact assessment (RIA) are identified, the main indicators of the state program “Providing affordable and comfortable housing and communal services to citizens of the Russian Federation (2013–2025)” are identified, a model for assessing the impact of programs on the sustainable development of housing and communal services is proposed, which determines the economic, investment, social, legal, environmental, innovative and digital influence of indicative factors. Provisions have been developed defining the organizational and methodological assessment of the impact of programs on the sustainability of the housing and communal services system and including the stages of selection and implementation of the main indicators of the program with an assessment of their positive impact on the sustainability and effectiveness of the development and functioning of the housing and communal services system.
State incentives for the transition to electric vehicles: trends in global experience
Authors:   National Research University «Moscow Power Engineering Institute», Buchnev A.O. , Buchnev O.A. ,   National Research University «Moscow Power Engineering Institute»
Published: June 2023

The article examines the world experience of state programs to stimulate demand and production of electric vehicles. The analysis of the competitive advantages of owning an electric car in comparison with the offers of the traditional automotive market is carried out. Individual examples of the benefits of using electric transport are considered in the context of the decarbonization processes of the world economy, as well as in general from the point of view of the formation of a new energy paradigm. The dynamics of the cost of the key element of an electric vehicle – the battery and its relationship with the market of energy storage systems are estimated. The connection with the most innovative directions of digital energy is shown.
Methods of regulatory influence as a tool to ensure the sustainable development of the housing and communal services
Authors:   Moscow Analytical Center  in the field of urban economy, Balashov E.B. , Kuzma I.E. ,   Moscow Analytical Center  in the field of urban economy
Published: June 2023

The article discusses the methods of regulatory impact on sustainable development through regulations, state federal, regional and municipal programs and projects on the example of the housing and communal complex (HCS). The general shortcomings of the programs that can reduce the effectiveness of their implementation are shown. The most effective options for methods and approaches to influence the sustainable development of housing and communal services have been identified, allowing to determine the economic, investment, social, legal, environmental, innovative and digital impact of factors. A conceptual model of organizational and economic sustainability of housing and communal services development is proposed. To adapt the regulatory impact methodology, a methodological approach has been developed for the regulatory impact of programs and projects on the sustainable functioning of the housing and communal services.
Reduction theloss of electrical energy during transmission and distribution through electric networks is a priority in the digitalization of the electric power industry, the constructionand digital economy of the Russian Federation
Authors:   Joint Stock Company «Institute  of Regional Economic Research», Poletaev I.Yu.
Published: June 2023

The problem of reducing losses of electric energy during transmission and distribution through electric networks is one of the key tasks for most electric grid companies in Russia. The task of developing remote control technologies has actually been set by the Government to all subjects of the electric power industry in the regions of Russia. The article discusses the issues of the introduction of IT technologies as measures to reduce the loss of electrical energy during its transmission over networks. Proposals have been developed on the organizational, investment and economic components of creating electric systems with an intelligent network in our country.
Development and Validation of RP-HPLC Method for Determination of Febuxostat in Bulk and Pharmaceutical Dosage Formulations
Authors: R. Kamble Pragati , V. Pandagale Nikita , D. Ghatage Omkar , B. Patil Pramod , Patil S. V.
Published: June 2023

A new accurate, specific, precise, high performance liquid chromatographic (HPLC) method has been developed and validated for the determination of Febuxostat in bulk and in its pharmaceutical dosage forms of tablet. Acetonitrile: Methanol (70:30) was used as the mobile phase at a flow rate of 1.0ml/min using a Symmetry C18 column Finepack SIL C18T-5 (250x4.6mm, 5m). The effluent was spectroscopically monitored at 314nm. The intraday and inter-day precisions showed coefficients of variation ranged from 0.62% to 2.78% at different levels of concentrations. The calibration curve was linear with a correlation coefficient of 0.9947. The averages of the absolute and relative recoveries were found to be 98.67% to 98.96%. The proposed HPLC method was successfully applied to quantify the amount of Febuxostat in bulk and dosage forms in quality control.
Stability Indicating HPTLC Method Development and Validation for Estimation of Nortriptyline and Pregabalin in Tablet Dosage Form
Authors: Ghogare Jyoti D. , Panchal Pranita P. , Rathod Sayali P. , Jadhao U. T.
Published: June 2023

Chromatography is non-destructive procedure for resolving a multi-component mixture of solids, gases, Liquids. HPTLC is use of validated methods for qualitative and quantitative analysis. HPTLC is playing an important role in analytical world and a complementary method for HPLC. The analytical method was evaluated by using parameters such as Linearity, Precision, Accuracy, Limit of detection and Limit of quantification, Specificity, Robustness. In this method 100ng µL-1 and 750ng µL-1 volume of standard stock solutions of Nortriptyline and Pregabalin were taken, respectively. The mobile phase contains Toluene: Ethyl acetate: Methanol (6: 2: 1, v/v/v). Standard stock solutions were applied by over spotting on HPTLC plate with the help of CAMAG 100µl sample syringe, Linomat 5 sample applicator. The development chamber was saturated for 15 min. The plate was scanned at 210nm. The retention factors of PREGA and NORT were found to be PREGA: 0.48±0.03, NORT: 0.70±0.07. The % drug content (mean±S.D.) were found to be 99.32±1.39 for NORT and 99.75±1.15 for PREGA. The results of stress degradation studies revealed that NORT was prone to hydrolysis, oxidative, thermal and photolytic degradation whereas PREGA was found susceptible to hydrolysis, oxidative, thermal degradation but stable under photolytic stress conditions.
LC–Tof-Ms an Influential Hyphenated Technique and its Application
Authors: Pankaj Pankaj , Kumar Pramod , Kapoor Aman , Priyanka Priyanka , Kumar Puneet , Kumari Saweta
Published: June 2023

LC-TOF-MS is powerful analytical technique. It is a combination of two techniques one of which is belongs to chromatography and other is from spectroscopy. Chromatography is separation technique and perform both techniques separately it is very time consuming but combined both techniques to save time and provide better results. This represents the potential of liquid chromatography with (quadrupole) time-of-flight mass spectrometry [LC-(Q)TOF-MS] in examining the presence of pesticide metabolites in food and water samples. This method portrays a quick enhanced screen for blood and urine specimens in post-mortem, driving under the influence and drug facilitated sexual assault forensic toxicology casework. (LC–MS) is an analytical technique that amalgamate the physical separation capability of liquid chromatography with the mass analysis capability of mass-spectrometry (MS).This technique can be used in analysis of pharmacokinetics, proteomics/metabolomics, development drug, analysis of pesticides in vegetables, analysis of medicinal panaxherbs for metabolomic research, identification of diphenhydramine in segment sample, investigation of pesticides metabolites in food and water etc.
Degradation of thiobencarb and propanil in an herbicide and their effects on bacterial community in soil
Authors: Huynh Thi Thanh Thuy , Nguyen Thanh Hung , Tran Ngoc Chau , Ha Danh Duc
Published: June 2023

Diuron has been widely applied to control weeds causing serious environmental pollution. In the current study, the mixed culture of three bacterial isolates, Bacillus subtilis DU1, Acinetobacter baumannii DU, and Pseudomonas sp. DUK, was investigated for diuron degradation in a packed reactor and soil. The immobilization of the bacteria mixture in rice straw increased the degradation. The specific degradation rates of diuron by bacteria immobilized in rice straw in batch cultures increased from 0.38 ± 0.03 mg/L at the first cycle to 0.98 ± 0.10 mg/L at the fourth cycle. The degradation using the reactor was also carried out in a continuous operation. Moreover, the introduction of bacteria into soil increased diuron degradation. This study shows the potential of diuron degradation in the reactor and in soil using the mixed bacterial culture immobilized in rice straw.
Impact of Teacher Home Visit Tutoring on High School Students’ Mathematics Performance: Basis for Adopting an Intervention Program for Struggling Learners During the Pandemic
Authors: Magdayao Arvee Grace Sejas , Fabonan Jorge Paelma , Tajolosa Teresita Domino , Injan Red Gel Linn Castillo
Published: June 2023

Amidst the risk brought by the COVID-19 pandemic in the Philippines, the country’s educators, students, and schools managed to continue education through distance learning. This study explored the effects of teacher home visit tutoring on improving high school students’ performance in mathematics. A researcher-constructed pre-test and post-test and a modified adopted survey questionnaire were personally administered to the respondents. Through the use of MS 365 Excel and Jeffrey’s Amazing Statistical Program or JASP software, it was found that there was a significant difference between the respondents’ scores before and after the home visitation tutoring. Further, respondents perceived an improvement in their performance after being home tutored by their teachers, and positively perceived the suitability and timeliness of the tutoring strategy.
Meaningful Drills and Contextualized Reading Passages to Understand Relative Clauses
Authors: Mustafa Abbas Eltahir , Fadellah Abdelbadie Ahmed
Published: June 2023

The current study tries to test the assumption that the use of meaningful drills and contextualized reading comprehension passages lead to better understanding of relative clauses. The study is based on the idea that meaning and contexts are necessary for learning to take place. It also aims to empirically test the effect of meaningful drills proposed by Christina Paulston on the acquisition of relative clauses. A sample of (30) first year undergraduate students of English took part in this study. The participants were divided equally into experimental and control group. The sample performances were matched based on their scores in the pre and posttest. After doing the pretest the experimental students received a short handout with relative clauses presented in short reading passages to read for themselves. Students of the experimental group had to identify and discover for themselves the occurrences of relative clauses in the reading passages. The reading passages are followed by meaningful drills on relative clauses. Three weeks later, the students in both groups took a posttest on relative clauses. Based on the tests results the authors have concluded that inserting context and meaning leads to better understanding of the grammar pattern being investigated.
Financial Analysis of Eritrean Commercial Bank: CAMEL Model
Authors: Tewelde Hosie G. , Kiflemariam Hewan , Aregawi Natnael , Ghirmay Surafiel
Published: June 2023

Research on Eritrean banking system is scant. Hence, this study’s aim is two-fold. To add literature to this scarce body of knowledge and to initiate the CAMEL model in the Eritrean context. The main purpose of this paper is to evaluate the performance of the Commercial Bank of Eritrea (CBER) using CAMEL approach. Data are gathered from consolidated financial statements of CBER. The analysis extends for 15 years starting from 2001 up to 2015 by employing two variables from each CAMEL parameter. Based on the selected CAMEL metrics the empirical analysis depicted a satisfactory result but with significant volatilities. Except for Capital Adequacy which is probably tied to its ownership structure Asset Quality, Management Efficiency, Earnings and Liquidity portrayed reasonable outcomes, nonetheless with frequent head and shoulder trends. These sheds light on the strengths and vulnerabilities of the bank, underlining the need to bolster the concerns of the decision makers to improve and increase its soundness.
Tasavvufta İnsan ve Toplum İnşasına Sosyolojik Bir Bakış: Şeyh Şerafeddin Dağıstanî Hazretleri
Authors: SAĞLIK Sema
Published: June 2023

Tasavvufta insan ve toplum inşasına bir örnek olarak verilen Nakşbendi tarikatının Halidî kolunun önde gelen mürşidi Şeyh Şerafeddin Dağıstanî Hazretlerini konu alan çalışmanın ilk bölümünde teorik çerçeve başlığı altında tasavvuf ve tarikatlar; özelde ise Şeyh Şerafeddin Dağıstani Hazretlerinin dini ve sosyo-kültürel hayatı hakkında bilgi verilmiştir. Bu çalışma teorik ve pratik olmak üzere iki şekilde ele alınmıştır. Araştırmanın teorik yönünde kitaplara ve makalelere başvurulmuştur. Tarikatların toplumsal işlevi ile ilgili kitaplar, makaleler, tezler, süreli yayınlar, web sayfaları vb. kaynaklar taranmıştır. Çalışmanın pratik yönünde de katılımlı gözlem tekniği kullanılmıştır. Genel bir değerlendirme yapıldığında tasavvufun bir yaygın eğitim modeli olduğu; insan ve toplum inşasının zemininde icra-i faaliyet gösterdiği söylenebilir. Ayrıca Şeyh Şerafeddin Dağıstani Hazretlerinin Yalova’da yaptığı irşad faaliyetleri ve Kurtuluş Savaşının başladığı yıllarda Türkiye Büyük Millet Meclisi’ne vermiş olduğu manevî desteğin tarihî önemi büyüktür.
Din Kültürü ve Ahlak Bilgisi Dersi (4-8. Sınıflar) Öğretim Programının Yorumlayıcı Din Eğitimi Yaklaşımı Açısından Değerlendirilmesi
Authors: FAKİOĞLU BAĞCI Hatice
Published: June 2023

Bu çalışmanın amacı, yorumlayıcı din eğitimi yaklaşımını incelemek ve Türkiye’deki ilk ve ortaokullarda yer alan Din Kültürü ve Ahlak Bilgisi dersinin (4-8. sınıflar) öğretim programının bu yaklaşıma uygunluğunu tartışmaktır. Bu amaç doğrultusunda çalışmada, yorumlayıcı din eğitimi yaklaşımının meydana çıkışı ve gelişim süreci incelenmiştir. Daha sonra bu yaklaşımın anahtar kavramları ve temel varsayımları ele alınmış, güçlü ve zayıf yönleri belirtilerek yaklaşıma getirilen eleştirilere yer verilmiştir. Son kısımda ise ilk ve ortaokullardaki zorunlu Din Kültürü ve Ahlak Bilgisi dersinin (4-8. sınıflar) mevcut öğretim programı yorumlayıcı din eğitimi bakış açısıyla değerlendirilmiştir. Söz konusu programın büyük oranda İslam dinine dayalı olduğu ve çoğulcu bir karaktere sahip olan yorumlayıcı din eğitimi yaklaşımıyla uygunluk arz etmediği sonucuna varılmıştır. Türkiye’de muhtemel bir program değişikliğinde yorumlayıcı din eğitimi yaklaşımından yararlanılabileceği ifade edilmiş, bu yaklaşımın model alınması halinde içerdiği imkân ve sınırlılıklar tartışılmıştır. Bu çalışma nitel bir araştırma olup, yöntem olarak doküman incelemesi kullanılmıştır. Yorumlayıcı din eğitimi yaklaşımı ve Din Kültürü ve Ahlak Bilgisi dersi öğretim programına dair literatür taranıp incelenmiş, toplanan veriler araştırmanın problemi çerçevesinde içerik analizi ile yorumlanmıştır. Çalışmanın sonunda ise yorumlayıcı din eğitimi yaklaşımına uygun bir şekilde hazırlanmış öğretim programları ve ders kitaplarının ayrıntılı bir şekilde incelenmesi ve ülkemiz örgün din eğitimi için bir uyarlanma çalışması yapılması önerilmiştir.
Unmasterful Spirituality: Challenging Ancestor Worship
Authors: Ilek Kristýna
Published: June 2023

This essay explores the spiritual and performative practice of ancestor worship as revisited by Czech-Vietnamese queer artist Lê Thị Hoài. The essay unpacks the power dynamics at stake in Lê Thị’s practice and introduces spirituality as a challenge to established power hierarchies. Lê Thị’s artistic work is inspired by her experience of the entanglements, complexities, and conflicts that her heritage—personal, cultural, social, and political—brings to her. The essay draws on Julietta Singh’s rethinking of “mastery” to interpret Lê Thị’s work as “unmasterful.” It looks at the symbolism, form, material, and function in Lê Thị’s work and juxtaposes the contradictory political, social, and economic beliefs that she strives to overcome. The author argues that the subversiveness of performative revision of traditional rituals is constituted through not only challenging an established system of values but also bringing to the forefront the ambiguity between the politics of private and public spaces and understanding spiritual force as an equal element in the art piece.
Frequency of Rare Bleeding Disorders
Authors: Khan Naveed , Kashif Nadia , Shah Hamidullah , Baloch Sabah Kaleem , Shah Munawar Ali , Syed Fareeha Naseer
Published: June 2023

Objective: The incidence and range of rare hereditary bleeding diseases, as well as the severity of the deficiency and its many clinical presentations, were the subjects of our study. Study Design: Cross-sectional study Place and Duration: Department of Pathology, Northwest School of Medicine Peshawar in the duration from July, 2022 to December, 2022. Methods: Total 850 cases of coagulation disorders were presented in this study. A thorough demographic analysis of the recruited cases was done after receiving informed written consent. After taking note of the symptoms and indicators, a coagulation profile was used to diagnose the patients. With the use of factor tests, the illness severity was evaluated. All of the data was examined using SPSS 23.0. Results: Among 850 cases, 113 (13.3%) patients were had rare bleeding disorders. In 113 cases of rare bleeding disorders, there were majority 70 (61.9%) males and 43 (38.1%) patients were females. Mean age of the cases was 10.5±13.69 years. 47 (41.6%) cases were from urban areas and 66 (58.4%) cases had rural residency. Most common deficiency was factor VII found in 33 (29.2%) cases followed by fibrinogen in 22 (19.5%) cases. 17 (15.04%) cases had family history of rare bleeding. Frequency of consanguinity was found in 88 (77.9%) cases. Most common clinical symptom was bruising, gum bleeding, epistaxis and menorrhagia. Conclusion: We concluded higher frequency of rare bleeding disorders in 13.3% cases. Factor VII deficiency is the most typical uncommon bleeding condition in our community. Due to the high rate of consanguineous marriages in our society, these bleeding diseases are very common. Keywords: Factor deficiency, Rare bleeding disorders, Factor assay, Consanguinity
Efficacy of Clomiphene Citrate Alone Versus Clomiphene Citrate Plus Metformin in Anovulatory Infertility in Polycystic Ovarian Syndrome
Authors: Rafiq Tanzila , Hayat Naheed , Zainab Sadia , Maqsood Sumaira
Published: June 2023

Objective: To compare the efficacy of clomiphene citrate and clomiphene citrate with metformin in anovulatory infertility with PCOS (polycystic ovarian syndrome (PCOS). Study Design: Randomized controlled trial. Place and Duration of Study: This research took place in the Department of Gynecology and Obstetrics at the combined military hospital Bahawalpur. The study was carried out over a six-month period, starting on 1st November 2022 and concluding on 30 April 2023 Materials and Methods: The study comprised 176 married women aged between 18 and 40 years who had been experiencing anovulatory infertility and PCOS for more than 6 months. In group A, for a period of three menstrual cycles, patients received 500 mg of metformin three times a day consistently and 100 mg of clomiphene citrate daily from the fifth to the ninth day of their menstrual cycle. In contrast, patients in group B were given 100 mg of clomiphene citrate daily from the fifth to the ninth day of their menstrual cycle for up to three months. We recorded and analyzed the treatment efficacy for all participants in both groups. Results: In this study, the metformin and clomiphene combination showed a 71.59% ovulation rate compared to clomiphene alone (39.77 %). The pregnancy rate was 31.82% with clomiphene citrate (CC) and 64.77% with a combination (clomiphene citrate and metformin). Efficacy in the study was observed in 57 (64.77%) patients treated with metformin and CC. group and 28 (31.82%) patients in the clomiphene citrate alone group (p = 0.002). Conclusion: The findings from this study suggest that the combination of clomiphene citrate and metformin demonstrated superior efficacy compared to the use of clomiphene citrate alone in treating anovulatory infertility associated with polycystic ovary syndrome. Keywords: Polycystic ovarian syndrome, clomiphene citrate, metformin.
Effect of Whole Body Vibration Therapy on Spasticity, Balance, Fine and Gross Motor Functions in Patients with Spastic Cerebral Palsy: A Systematic Review of RCTs
Authors: Hassain Syed Ali , Hassan Zainab , Rasanani Mohammad Reza Hadian , Afzal Rabia , Khan Nouman , Zaib Hussein Mohamad Ahmad
Published: June 2023

Context: Cerebral palsy is condition that is caused by neurological damage, which leads to problems in the somatosensory systems. It can cause spasticity in the involved muscles leading to poor function, limitations in range of motion, poor balance and coordination. Therapeutic use of whole-body vibration therapy for the management of the mentioned symptoms have been reported in the literature. This review study examines the effect of whole-body vibration on spasticity, balance and function and summarizes the effective protocols of whole-body vibration therapy for the cerebral palsy patients. Methods: Three following databases were searched comprehensively: Pubmed, PEDro and Cochrane. The selection criteria for the research papers were based on; (1) human studies with Patient-Intervention-Comparison-Outcomes-Study design (PICOS) method, according to which, P = spastic cerebral palsy; I = Whole Body Vibration; C = comparison with conventional/traditional physiotherapy; O = dynamic balance, spasticity, functional balance, fine and gross motor hand function, hand grip strength, Balance Quantification and Range of Motion; and S = Randomized controlled trials, (2) Published in English Language (3) Full Text Available (4) The PEDro scale on which the score is greater than 4 out of 10. Results: Nine RCTs were included based on the inclusion criteria. This systematic review showed that whole body vibration therapy can produce positive therapeutic effects on spasticity, balance, fine and gross motor function, muscle strength and range of motion. This modality can be used independently or in combination with the conventional physical therapy. No harm has been reported in the literature. Conclusion: It can be concluded that whole body vibration therapy is safe, cost effective and fairly simple therapeutic modality that can be used at home or in clinical settings to produce a significant change in spasticity, static and dynamic balance, motor function and range of motion. Keywords: Balance, Cerebral Palsy, Motor Function, Spasticity, Whole body vibration therapy
Complications in the Treatment of Mandibular Condylar Fracture, Surgical Versus Non-Surgical Treatment
Authors: Khan Tehreem , Shabbir Maria
Published: June 2023

Background: The facial fractures include Condylar fractures are most common in mandibular fractures, which have the highest fracture incidence after nasal bone fractures. Three different traumatic forces can result in condylar injury: the first is energy imparted to a static person by a moving object, such as a blow to the face from a cricket bat; the second is a moving person striking a static object, such as a child falling and striking the ground; and the third is a combination of the first two forces, such as when a person is moving and an automobile is moving and is hit by an automobile. This kind of force typically has the biggest impact and causes the most severe injury patterns. Objective: To compare frequency of Complications of two procedures for the treatment of mandibular condylar fracture surgical versus conservative treatment. Methodology: This Randomized control trial was held in the Tertiary Care Hospital Karachi for 6 months from 12 Jul, 2019 to 12 Jan, 2020. ERC were taken before data collection. Patients suffering from mandibular condylar fracture and fulfilling exclusion and inclusion criteria and who were ready to give informed consent after explaining study protocol, risk benefit ratio and data usage for research were included in our study. The first group labelled as "A" was treated by closed reduction and immobilization and second group labelled as group "B" was undergone internal fixation and open reduction. Results: The mean age and standard deviation of the 72 patients was determined to be 40.85 ± 12.93 years, respectively, with the 18 years was the minimum age and the 65 years being maximum. Frequency of gender was shown in Graph 1.The minimum duration of fracture was 1 day, and maximum were 7 days. The minimum mouth opening was 15mm and maximum was 35mm (Table 1). Trismus was present in 5/72 (6.9%) patients while it was absent in 67/72 (93.1%) patients (Table 2). Malocclusion was present in 20/72 (27.8%) patients while it was absent in 52/72 (72.2%) patients. Unilateral Side of fracture was present in 40/72 (55.6%) patients while Bilateral was present in 32/72 (44.4%) patients (Table 3) Conclusions: In conclusion, closed reduction had clinically satisfactory results, although open reduction and internal fixation produced more accurate to reduce the complications. Keywords: Closed reduction, Internal fixation, Open reduction,complications
Understand How Diabetes Contributes to the Development of Kidney Disease: A Single Center Study
Authors: Khan Rahmat Ali , Haq Mazhar Ul , Shahid Muhammad , Munib Syed , Wahab Fazli
Published: June 2023

Background: This study investigates the relationship between Diabetes and renal disease. It will review the epidemiological patterns of diabetes-related kidney disease and how various treatment choices, lifestyle changes, and expanding preventative measures might lower the risk of kidney disease in diabetics. Additionally, it will go through the symptoms and effects of kidney disease on those with Diabetes and the likelihood of effective treatment and preservation of kidney function. We'll also discuss how this study may affect patients, healthcare professionals, and decision-makers. Methodology: From January 2022 to January 2023, this research was carried out in the nephrology department of the Miangul Abdul Haq Jahanzeb renal hospital in Swat. The study identified pertinent themes on how Diabetes leads to the development of kidney disease by using several sources, including medical papers, news articles, and web resources. The Cochrane Library and PubMed, and other pertinent research sources were examined. Additionally, qualitative interviews with healthcare experts were done, including endocrinologists, nephrologists, and other medical specialists with knowledge of Diabetes and kidney disease. Results: According to the findings, Diabetes considerably raises the risk of renal disease. Glomerulonephritis, diabetic nephropathy, and hypertension-related kidney disease accounted for most kidney conditions associated with Diabetes. Options for treatment exist to lower risk factors, control kidney disease complications, and enhance general health and well-being in people with Diabetes. The most significant lifestyle changes that people with Diabetes may do to lower their risk of kidney disease include weight reduction, regular exercise, a healthy diet, quitting smoking, and consuming less salt and alcohol. A further key role in lowering the risk of kidney disease and its development is the increased accessibility of preventative methods, such as good pre-diabetes and diabetes screening, optimal diabetes treatment, and vaccination against influenza and pneumococcal illness. Conclusion: Diabetes has a significant role in the development of renal disease. The increased accessibility of preventive screening, proper diabetes management, and immunization against infectious diseases play an important role in lowering the overall risk of developing kidney disease in people with Diabetes, even though treatment options and lifestyle changes exist to reduce risk factors for the disease's progression. Keywords: Epidemiology, risk factors, therapy, lifestyle changes, preventive, healthcare providers, pre-diabetes screening, diabetes management, vaccination, renal disease
Investigating Risk Factors for Kidney Stones in Department of Nephrology Saidu Teaching Hospital Swat
Authors: Fahad Shah , Haq Mazhar Ul , Shahid Muhammad , Munib Syed , Wahad Fazli
Published: June 2023

Objectives: The main objective of this study is to investigate the risk factors associated with kidney stones in the Department of Nephrology, Saidu Teaching Hospital, Swat, from Jan 2021 to Jan 2022. Specific objectives of this study are to: 1. Identify and examine the demographic, medical and lifestyle factors of patients with and without kidney stones. 2. Analyze the risk factors for the different types of kidney stones. 3. Determine the relative risk of each risk factor for kidney stone formation. 4. Make suggestions for prevention and management strategies of kidney stone development. Methods: This study was a retrospective case-control study in the Department of Nephrology, Saidu Teaching Hospital, Swat, from Jan 2021 to Jan 2022. Patient records from this period were reviewed and demographic, medical, and lifestyle factors of patients with and without kidney stones were compared. Risk factors for stone formation were determined using univariate and multivariate analyses. Statistical analysis was conducted using the chi-square test, Fisher’s exact test, and logistic regression. Results: A total of 193 patients of various ages had been admitted to the nephrology department from Jan 2021 to Jan 2022; 10 of these had a kidney stone. Of the kidney stone patients, six (60%) were male and four (40%) were female. The mean age of those with kidney stones was 43.6 years. Of the risk factors analyzed, male sex, family history of stone disease, diabetes, hypertension, and certain lifestyle factors such as drinking soft drinks and eating a diet high in animal proteins were significantly associated with stone formation. Conclusion: This study identified a number of risk factors associated with the formation of kidney stones in the nephrology department of Saidu Teaching Hospital between Jan 2021 to Jan 2022. Male sex, family history of stone disease, diabetes, hypertension, and certain lifestyle factors such as drinking soft drinks and consuming a diet high in animal proteins were found to be significantly associated with stone formation. Further research is needed to gain a better understanding of these risk factors and develop prevention and treatment strategies for kidney stone formation. Keywords: Kidney Stones, Risk Factors, Department of Nephrology, Saidu Teaching Hospital
A RECEPTION ANALYSIS ON THE CONCEPT OF GROUP INTERACTION IN THE MOVIE 12 ANGRY MEN
Authors: BAL Canan Gamze , AVCU Gökçen
Published: June 2023

Undoubtedly one of the factors that play a key role in the success of the organization is the activity of the groups of employees. To what extent and with which concepts the blue-collar and white-collar employees in these groups perceive the interaction within the group is important for organizational success. This study was designed to reveal the perspectives of blue-collar and white-collar employees on the concepts of group interaction through the reception analysis of the movie “12 Angry Men”. In the study carried out with 29 people, in-depth interviews were conducted and the results were analyzed. In this process, four phases defined by Denzin (2004) for organizing the analysis of films and television programs are taken into account. Considering the percentages of blue-collar employees in intragroup interaction categories, prejudice and leadership/minority effect are in the first place. When this result was compared with the reception percentages of the white-collar employees, it was seen that the first reception category of the white-collar employees was prejudice, and then the leadership/minority influence was equally group dynamics and decision making, culture and gender categories. While there is not a big difference in reception in the categories of adaption and aggression in the group interaction, the difference in the category of social cognition is quite large. Another result is the persuasion and imposition categories, where blue-collar employees in the persuasion category and white-collar employees in the imposition category seem to make more purchases. In the study, it was determined that the audience was very sensitive to the messages. The findings showed that the position studied plays a role in producing different meanings.
Obesidad, inflamación y glucocorticoides
Authors: Papapietro V. Karin , Guerrero P. Julia
Published: June 2023

Obesity is a worldwide problem that also involves our country. It reduces life expectancy

and represents a high economic burden for individual and the society. A large amount of

economic and human resources has been allocated for obesity control and prevention. Obesity

is associated with the main non-transmissible diseases on this time: cardiovascular diseases,

type 2 diabetes mellitus, arterial hypertension, osteoarticular disease and some types of

cancer. The development of obesity include genetic, environmental and lifestyle factors. While

lipid accumulates into the adipocyte, it becomes in a tissue with hypertrophy and hyperplasia

and inflammatory cells infiltrate it. Although it is not known the primary stimulus that triggers

this inflammatory phenomenon, it is known this has deleterious consequences in the local and

systemic metabolism and give the obese phenotype with insulin resistance, atherogenesis

and inflammation. Glucocorticoids are steroidal hormones with multiple actions such as anti-

inflammatory properties. In obese patients, even when the plasma level of cortisol may be

normal, glucocorticoids are unable to achieve regulation of the pro-inflammatory state that

characterizes it. Bariatric surgery, along with recovering the weight, has been found to resolve

systemic inflammatory status. The relationship between bariatric surgery, weight recovery and

glucocorticoid activity has not been studied yet.
Genética y genómica en la atención de salud
Authors: Castillo T. Silvia
Published: June 2023

The adequate use of information on sequences of the genetic material in human and other

organisms, as well as technological innovations, will allow significant advances in our

understanding of genetically based diseases and, more importantly, how health care is managed.

We review the main topics in Genomic Medicine and the skills required in health professionals to

apply them. Rare Diseases arise as a health issue in a country with good general indexes like

Chile and concerns around one million Chileans at some point in their lives. It emphasizes the

importance of sharing data to make progress in knowledge and management, while keeping

confidentiality measures. Some preliminary strategies are outlined in Chile to confront Genomic

Medicine. The position of the American College of Medical Genetics and Genomics (ACMG)

is presented to the possibilities offered by the development of new technologies such as

genomic editing.
Serie guías clínicas: complicaciones del embarazo gemelar monocorial
Authors: Sepúlveda-Martínez Álvaro , Valdés R. Enrique , Parra-Cordero. Mauro
Published: June 2023

Conocer las complicaciones específicas de gestaciones monocoriales.

Reconocer las formas de presentación de la restricción selectiva.

Identificar los hallazgos ecográficos para clasificar la transfusión feto-fetal.

Comprender las eventuales complicaciones perinatales del gemelo sobreviviente en casos de

cogemelo muerto.

Conocer el manejo integral de las gestaciones monocoriales
Conocimiento y actitud frente a exposición solar del personal de salud en Atención Primaria, comuna Recoleta, Santiago, Chile
Authors: Contreras N. Andrés , Zemelman D. Viviana , Zamudio M. Andrea
Published: June 2023

Introduction: Skin cancer rates have increased worldwide despite the current prevention

measures. It’s crucial to evaluate people’s knowledge, attitudes, and behaviour regarding

sun exposure. Objective: To assess the knowledge and attitudes regarding sun exposure

in the workers from primary health care. Method: 223 workers from three Family Care

Centres(CESFAM) and from one Primary Emergency Service (SAPU) in the district of Recoleta

were surveyed between the months of October and November 2015. Fisher’s exact test

and Chi square test were used for statistic analysis. The survey included questions about

demographic variables, knowledge of the association between sun radiation/skin cancer and

attitudes towards sun protection. Results: the sample consists of 74 men and 149 women,

with a mean age of 37 years ±SD 7.9. Phototype III was the most common (41.3%). The

majority of the surveyed declared to be aware of the association between sun exposure and

skin cancer (93.3%). As photoprotecting measures, sunscreens (87.4%) and seeking shade

(71.3%) were the most frequently measures used. Regarding sunburns, 91.9% declared to

have at least one during their lifetime, 21.5% occurring during the previous summer. As to the

use of sunscreen, 42.1% referred only using while at the pool / beach and 12.6% declared

not to use it at all. As for health promotion, 29.1% declared they never recommend the use

of sun protection measures in their working practice. Discussion: Although there is adequate

knowledge regarding the effects of sun exposure, it doesn’t always reflect on favourable

attitudes and photoprotecting measures. There was a significantly greater amount of females

with adequate knowledge and use of sun protection measures. This study is one of the first to

assess photoprotection behaviour in health care workers.
Infarto agudo al miocardio en octogenarios, caracterización y comparación con pacientes menores en 20 años de registro
Authors: Ugalde P. Héctor , Sanhueza F. Maria Ignacia , Yubini L. María Cecilia , Rozas A. Sebastián
Published: June 2023

Introduction: cardiovascular diseases are the main cause of death in Chile, being acute

myocardial infarction (AMI) the most frequent. Its incidence increases with age, so, as

the population gets older; a higher number of cases is expected. Despite this, AMI within

octogenarian patients (OP) has been understudied in our country and worldwide; there are

no specific guidelines for their management, only a few isolated studies that reveal the poor

applicability of the standard treatments indicated in AMI clinical guidelines. Objective: To

describe the clinical features, initial treatment, in-hospital evolution and five-year outcome of

OP with AMI, and compare them to patients under 80 years of age. Method: Consecutive

registration of all patients diagnosed with AMI that were hospitalized in our coronary unit

between 1988 and 2007. Description of clinical features, in-hospital and 5-year evolution of

all OP cases. Comparison to the younger group of patients through chi-square or t-student

tests, considering p-value
Pie diabético
Authors: Echeverría G. Valentina , Sotomayor L. Camila , Norambuena G. Mackarenna , Vidal V. Pamela , Campos G. Alejandro
Published: June 2023

The prevalence of diabetes has increased considerably, constituting a global epidemic today.

Many of these patients will develop chronic complications of diabetes, including diabetic foot,

which aggravates the patient’s clinical condition, decreases the quality of life and has a great

socioeconomic impact. The most important action to reduce the morbidity and mortality

associated with this pathology is the prevention of this complication, performing a proper

metabolic management and serial control of the patient, educating about self-care of the

feet. Once diabetic foot ulcer is present, the cornerstones of treatment are debridement of

the wound, management of any infection, revascularization procedures when indicated, and

discharge of the ulcer, all of the above in order to avoid amputation. This article intends to

make a review about the epidemiology, pathophysiology, classification, diagnosis, prevention

and management of diabetic foot oriented to the primary care doctor
Péptidos inmunogénicos del gluten en deposiciones. Nuevo método para evaluar la adherencia a la dieta en pacientes celíacos
Authors: Miranda B. Julio , Covarrubias R. Natalia , Araneda M. Gonzalo , Hurtado H. Carmen , Defilippi G. Claudia
Published: June 2023

Celiac disease (CD) is an autoimmune pathology caused by the ingestion of gluten in genetically

susceptible people, currently considered multisystemic. The treatment of CD is a lifelong strict

Gluten-Free Diet (GFD), which allows a symptomatic improvement in most patients and achieve

intestinal mucosa healing confirmed with histological study. The adherence to the GFD is

variable, arguing as possible factors related to failure the economic, cultural, social aspects

and the consumption of gluten inadvertently. The management of celiac patients contemplates

instructing in the proper follow-up of GFD and evaluating their adherence. So far, the only way

to assess adherence to GFD is through surveys, self-reports of eating habits and serology,

being the main disadvantage the subjectivity factor. Recently the immunogenic gluten peptides

have acquired relevance for the objective evaluation of the adherence to the GFD and the

measurement appears as an efficient and sensitive option to determine the gluten intake,

providing relevant information for the clinical management.
Ventajas de la medición de niveles plasmáticos de infliximab en pacientes con enfermedad inflamatoria intestinal
Authors: Rojas B. René , Covarrubias R. Natalia , Miranda B. Julio , Pérez de Arce O. Edith , Gompertz G. Macarena
Published: June 2023

Inflammatory bowel disease includes Crohn ́s disease, ulcerative colitis and unclassified

colitis. Conventional therapies used for treating these diseases are often insufficient or

contraindicated and biological agents have proved to be effective and safe in these cases.

Infliximab is a quimeric IgG1 monoclonal anti-tumor necrosis factor antibody that is capable

of inducing and mantaining clinical remission in patients with inflammatory bowel disease.

Despite its proven efficacy a considerable group of patients lose response requiring changes

in therapy. Serum Infliximab trough levels are correlated with clinical response, endoscopic

remission and mucosal healing in patients with inflammatory bowel disease. Monitoring and

adjusting therapy guided by drug serum levels have proved to be more cost-effective and safer

than empiric adjustments. Current international guidelines recommend the measurement of

Infliximab trough levels in the global evaluation and management of these patients to improve

treatment, avoid adverse events and unnecessary costs.
Serie guías clínicas: parto prematuro
Authors: Parra-Cordero Mauro , Sepúlveda-Martínez Álvaro , Valdés R. Enrique
Published: June 2023

Determinar factores de riesgo de parto prematuro espontáneo menor a 34 semanas.

Determinar las medidas de prevención de parto prematuro espontáneo menor a 34 semanas.

Conocer la alta tasa de falsos positivos del diagnóstico clínico de parto prematuro y el papel de la evaluación ecográfica del cérvix.

Conocer el concepto del uso de tocolisis en parto prematuro.

Valorar el papel de los corticoides y sulfato de magnesio en la reducción de morbimortalidad perinatal en el parto prematuro.

Evaluar el papel de los antibióticos en el parto prematuro con membranas íntegras.
Abstracts de publicaciones internacionales ISI 2016
Authors: Hospital Clínico Universidad de Chile Revista
Published: June 2023

El material que se presenta a continuación proviene de los datos proporcionados por la OAIC (Oficina de

Apoyo a la Investigación Clínica) de nuestro Hospital, así como de los recolectados por nuestra Revista.
Dolor cervical como presentación de neumomediastino espontáneo en urgencia pediátrica. Caso clínico
Authors: Guzmán N. Miguel , Osses M. Gabriela
Published: June 2023

Spontaneous Pneumomediastinum is a rare clinical situation in pediatric emergency services, sometimes it presents with guiding symptoms, but in other occasions in a very nonspecific way. Definitely, needs to be highly suspected, emphasizing in the anamnesis the antecedent of intense physical exercise before the development of the triggering symptoms that determinates the consult, generally having a good evolution that gets solved in 3-4 days. There is a pediatric clinical case presented, that permits us to discuss the more relevant aspects of the clinical presentation, diagnosis methods and the updated management, in pediatric emergency services.
Hallazgos imagenológicos en la enfermedad pleuropulmonar asociada al asbesto
Authors: Weisz C. José , Hasson A. Daniel , Palavecino B. Tamara
Published: June 2023

Abestos-related pleuropulmonary disease involves a number of pathologic conditions that share inhalation exposure to asbestos fibers as a common factor. Dose and time of exposure have a role in the clinical manifestations of it, the main ones being benign pleural disease, asbestosis, malignant mesothelioma and bronchogenic carcinoma. Despite the ban on asbestos material usage in Chile, there is a long latency between exposure and clinical manifestations, which lead to it being still a relevant public health issue to this day. We present a series of representative images of abestos-related pleuropulmonary disease diagnosed at our centre. The pathogeny and radiologic manifestations are discussed, with an emphasis on the latter.
Tomosíntesis digital mamaria: puesta al día
Authors: López P. Alejandra , Castillo M. Ángela , Buttinghausen G. Valeria
Published: June 2023

Conventional mammography has been used for decades for breast cancer screening. Its limitations are well known and are partly related to the fact that with conventional imaging, the three-dimensional volume of the breast is imaged and presented in a two-dimensional format, which leads to low sensitivity in detecting some cancers and high false-positive recall rates. Digital breast tomosynthesis consists in the acquisition of several low dose images from slightly different angles which are then sent to a computer that uses the data to generate 3-D images, providing breast images which are virtually free from superimposition. This is in particular important in cases of high mammographic density to differentiate real masses and architectural distortions from the overlying parenchyma. Digital breast tomosynthesis has shown decreased false-positive callback rates and increased rates of cancer detection, resulting in increased sensitivity and specificity, without a significant increase in the radiation dose.