bluuebunny/crossref_metadata_2025 huggingface dataset:
Guidelines for the Diagnosis and Treatment of Rotator Cuff Tear with
Integrated Traditional Chinese and Western Medicine
Authors: Zeng Ling-Feng , Zhang Xian-Quan , Yang Wei-Yi , Liu Jun
Published: January 2024

Rotator cuff tear is a common injury among middle-aged and elderly people, and it
has a great impact on patients' physical and mental health and quality of life. Integrative medicine
based on Traditional Chinese Medicine (TCM) has certain advantages in the diagnosis and
treatment of rotator cuff tears. TCM, which mainly involves the use of plant-based products, has
relatively stable and reliable curative effects. It is of great significance to formulate a combined
diagnosis and treatment plan for rotator cuff tear based on evidence-based medicine, which can
help to standardize the clinical diagnosis and treatment techniques of TCM and Western medicine
and achieve better therapeutic effects. This guideline standardizes the diagnosis and treatment
process of rotator cuff tear from the aspects of range, terminology and definition, diagnosis,
TCM syndrome differentiation, treatment, functional exercise, and prevention and care. It
makes recommendations that cover the adoption of manual therapy, acupuncture, and other integrative
medicine based on TCM. Users of these guidelines are most likely to include clinicians
and health managers in healthcare settings.
Electrochemical Sensors for Detection of Phytomolecules: A Mechanistic
Approach
Authors: Katiyar Deepti , Manish  , Saxena Pal Rashmi , Bansal Priya , Kumar Abhishek , Prakash Surya
Published: January 2024

High demand and ongoing technological advancements have created a market for sensors that is both varied and rapidly evolving. Bioactive compounds are separated systematically
to conduct an in-depth investigation, allowing for the profiling or fingerprinting of different
Plantae kingdoms. The profiling field is significant in elucidating the complex interplay of plant
traits, attributes, and environmental factors. Flexible technology advancements have enabled the
creation of highly sensitive sensors for the non-destructive detection of molecules. Additionally,
very specialized integrated systems that will allow multiplexed detection by integrating many
hybrid approaches have been developed, but these systems are highly laborious and expensive.
Electrochemical sensors, on the other hand, are a viable option because of their ability to accomplish exact compound detection via efficient signal transduction. However, this has not been investigated because of some obstacles to learning minimum metabolites' fundamentals and nonredox properties. This article reviews the electrochemical basis of plants, contrasting it with
more conventional techniques and offering both positive and negative perspectives on the topic.
Because few studies have been devoted to the concept of merging the domains, we've expanded
the scope of this work by including pertinent non-phytochemical reports for better report comparison.
Large B-cell Lymphoma with IRF4 Rearrangement in the
Nasolacrimal Duct: A Clinicopathological Study of One Case and
Literature Review
Authors: Chen Wang-xing , Wu Jun , He Jian-guo
Published: January 2024

Background:

Large B-cell lymphoma (LBCL) with interferon regulatory
factor 4 (IRF4) rearrangement (LBCL-IRF4) is a rare subtype of LBCL, with a high
prevalence in Waldeyer's ring as well as the neck, head and gastrointestinal lymph
nodes.

Materials and Methods:

patient with 2-month clinical symptoms of nasal obstruction
and facial swelling was reported in this short review. A nasal endoscopy examination
revealed a neoplasm in the inferior nasal meatus. Both CT and enhanced MRI showed
that a soft tissue occupied the nasolacrimal duct, with bone destruction, and extended
into the left nasal cavity and left lacrimal gland area. Then, a biopsy of the neoplasm in
the inferior nasal meatus was performed.

Results:

HE staining results showed that neoplastic cells presented diffuse growth
patterns, abundant cytoplasm, vacuole shape, lightly stained nuclei, and irregular
nuclear membrane. Immunohistochemistry staining results revealed MUM1(+), Bcl-
6(+), CD20(+), CD79α(+), and CD10(+). FISH analyses detected positive IRF4
rearrangement. LBCL-IRF4 was diagnosed in the patient. The patient received
treatment with four cycles of R‐CHOP and two times of rituximab, followed up for 2
years, and finally got complete remission.

Conclusion:

For the first time, we summarize the imaging and pathological features,
drug treatment, and curative effect of LBCL-IRF4 in the nasolacrimal duct.
1,2,4-Triazole-conjugated Fluoroquinolones as Potential Candidates for
New Antibacterial Agents
Authors: Uygun Cebeci Yıldız , Karaoglu Sengul Alpay
Published: January 2024

In this study, synthesis of 1,2,4 triazole-fluoroquinolone hybrid compounds was realized.
7a-d hybrid compound was obtained as a result of mannich reaction with 6a-b triazole compounds
norfloxacin and ciprofloxacin. 1H-NMR, 13C-NMR, Mass Spectrometry and Elemental Analysis
confirmed the structures of all synthesized compounds. The antimicrobial activities of all compounds
were investigated, and it was observed that 7a-d compounds, which are mannich bases, showed excellent activity.
An Effective Algorithm Based on Sequence and Property Information for
N4-methylcytosine Identification in Multiple Species
Authors: Zhang Lichao , Wang Xueting , Xiao Kang , Kong Liang
Published: January 2024

N4-methylcytosine (4mC) is one of the most important epigenetic modifications, which
plays a significant role in biological progress and helps explain biological functions. Although biological
experiments can identify potential 4mC sites, they are limited due to the experimental environment
and labor-intensive process. Therefore, it is crucial to construct a computational model to identify
the 4mC sites. Some computational methods have been proposed to identify the 4mC sites, but
some problems should not be ignored, such as those presented as follows: (1) a more accurate algorithm
is required to improve the prediction, especially for Matthew’s correlation coefficient (MCC);
(2) easier method is needed for clinical research to design medicine or treat disease. Considering these
aspects, an effective algorithm using comprehensible encoding in multiple species was proposed in
this study. Since nucleotide arrangement and its property information could reflect the sequence structure
and function, several feature vectors have been developed based on nucleotide energy information,
trinucleotide energy information, and nucleotide chemical property information. Besides,
feature effect has been analyzed to select the optimal feature vectors for multiple species. Finally, the
optimal feature vectors were inputted into the CatBoost algorithm to construct the identification model.
The evaluation results showed that our study obtained the highest MCC, i.e., 2.5%~11.1%,
1.4%~17.8%, 1.1%~7.6%, and 2.3%~18.0% higher than previous models for the A. thaliana, C. elegans,
D. melanogaster, and E. coli datasets, respectively. These satisfactory results reflect that the
proposed method is available to identify 4mC sites in multiple species, especially for MCC. It could
provide a reasonable supplement for biological research.
Concordance of Bronchoscopic and Radiological Findings in Suspected Lung Cancer and its Outcome- A Cross Sectional Study in a Tertiary Care Hospital
Authors: A.S. Arjun , H.J. Gayathri Devi , Jain Aditi
Published: January 2024

Background:

Bronchoscopy and CT thorax are the most common investigations utilized
to screen and diagnose lung cancer. Their individual utility in diagnosing lung cancer has
been described affirmatively in existing literature. Studies correlating the airway characteristics of
the two modalities in lung cancer are limited.

Objectives:

To analyze and characterize lung lesions bronchoscopically and correlate the same radiologically
by CT of the thorax and thus assess its positive predictive value.

Methods:

In this prospective study, 56 consecutive adults who presented to the Respiratory
Medicine Department at a tertiary care hospital in South India from November 2018 to June 2020,
having Clinico-radiological suspicion of malignancy and fulfilling study criteria, were recruited.
They were subjected to CECT of thorax and bronchoscopy. All bronchoscopic procedures were
performed using a protocolized number of passes for biopsy. The baseline demographic and clinical
data, findings of bronchoscopy and CT and biopsy reports were recorded. Cohen’s kappa coefficient
was used to estimate the agreement of findings on the two modalities. Statistical analysis
was performed using SPSS software.

Results:

Bronchoscopy was normal in 22.14% of cases, the corresponding CTs also revealed normal
airway. Bronchoscopy revealed airway lesions in 78.6% of cases; the corresponding CT revealed
airway abnormalities in only 46.41% of cases; among these, 52.1% of cases revealed an
exophytic growth. There was fair strength of agreement for the two modalities in the detection of
airway lesions of lung cancer. (k = 0.38, p = < 0.001). CECT thorax has a negative predictive value
of 44%, a sensitivity of 59.1% and a specificity of 100% at 95% CI in the detection of airway
lesions.

Conclusion:

CT may not be definitive in the evaluation of lung cancer, especially in those with
central disease. A combination of the two modalities may improve the diagnostic outcome in patients
with lung cancer.
Oxadiazole Derivatives of Diclofenac as an Anti-proliferative Agent for
B-cell Non-Hodgkin Lymphoma: An In vitro and In Silico Studies
Authors: Qayyum Shaista , Jabeen Almas , Ashraf Sajda , Seraj Faiza , Khan Khalid Mohammad , Siddiqui Rafat Ali , Ul-Haq Zaheer
Published: January 2024

Background:

Non-Hodgkin lymphoma of B cell origin is the common type of lymphoma-
related malignancy with poor response rate with conventional front-line therapies.

Aim:

The aim of the present study was to investigate the potential of new anti-inflammatory oxadiazole
derivatives of Diclofenac as an anti-lymphoma agent through in vitro and in silico approaches.

Method:

Anti-lymphoma potential was evaluated by alamar blue technique. MTT assay employed
for cytotoxicity. Gene and protein expression studies was performed by qRT-PCR and ELISA respectively.
Docking studies was performed by using MOE program.

Result:

Among five diclofenac derivatives, (II) showed promising anti-lymphoma effects, where it
inhibited the expression of BCL-2, p-38 MAPK and TGF-β in both follicular and Burkitt’s lymphoma
cells and was non-toxic against normal human fibroblast cells. The in silico studies against
BCL-2 revealed that the unsubstituted Sulphur group in (II) is involved in the crucial interactions
with the binding site residue.

Conclusion:

The compound (II) can be a potential therapeutic candidate for B-cell non-Hodgkin
lymphoma and deserves further development as a novel anti-lymphoma agent.
An Updated Review on the Role of Phytoconstituents in Modulating
Signalling Pathways to Combat Skin Ageing: Nature’s Own Weapons and
Approaches
Authors: Porwal Mayur , Rastogi Vaibhav , Chandra Phool , Shukla Swati
Published: January 2024

Various geographical areas exhibit varying degrees of prevalence and severity of dermatological
issues. The most commonly observed skin issues among adolescents during their growth
period on a global scale encompass dry skin, dyspigmentation, wrinkles, fungal infections, as well as
benign and malignant tumors. These conditions arise as a consequence of diminished functional capacity
and heightened skin susceptibility. The primary manifestation of the whole process of skin
ageing is its visual presentation, which encompasses changes in both the structure and function of the
skin. The look and function of human skin exhibit particular variations as individuals age, representing
a time-dependent phenomenon. This review article primarily examines the discussion surrounding
the diverse phytoconstituents and their impact on signalling pathways in cellular metabolism, as
well as their interaction with environmental factors and xenobiotic agents that contribute to skin
aging. Ultraviolet (UV) light induces the rapid formation and subsequent accumulation of reactive
oxygen species (ROS) within skin cells, hence accelerating oxidative stress and the ageing process of
the skin. One effective approach to addressing age-related skin disorders entails the utilization of
exogenous supplementation through the consumption of dietary antioxidants, as well as the application
of antioxidant-based lotions to the skin prior to sun exposure. Several plant species include phenolic
components, including ascorbic acid, ellagitannins, and carotenoids, which have the ability to
protect the skin from harmful UV radiation, reduce inflammation and oxidative stress, and influence
several survival signalling pathways. This comprehensive study elucidated multiple processes by
which phytoconstituents exert their effects for intervention purposes. Additionally, it highlighted the
ability of these phytoconstituents to modulate the NF-κB signalling pathway, MAPK signalling, Nrf2
signalling, and other pathways, hence demonstrating their potential anti-aging properties.
Semaglutide’s Neuropharmacological Effects: From Glycemic Regulation
and Weight Loss to Potential Implications in Substance Use Disorders – A
Narrative Review
Authors: Völker Jes Sebastian Denis , Micluția Ioana Valentina , Vinași Ramona-Cristina
Published: January 2024

This narrative review delves into the potential therapeutic implications of semaglutide, a
Glucagon-Like Peptide-1 (GLP-1) receptor agonist, in the context of Substance Use Disorders
(SUDs). By systematically exploring databases from 2011 to 2023, and incorporating foundational
works from 2004, a total of 59 articles were identified as pertinent to the topic. Utilizing the
SANRA scale for assessment, the quality and relevance of these studies were rigorously evaluated.
Preliminary findings indicate that semaglutide may play a pivotal role in modulating behaviors associated with SUDs, potentially providing fresh perspectives on the neurobiological mechanisms
underlying these disorders. While the precise pathways of action for semaglutide remain to be fully
deciphered, its recurrent mention in the literature underscores its emerging importance in the field
of SUD research. As the understanding of semaglutide's influence expands, it holds promise as a focal point in future studies, warranting further in-depth exploration to ascertain its full therapeutic
potential.
Light Sensitive Liposomes: A Novel Strategy for Targeted Drug Delivery
Authors: Aundhia Chintan , Parmar Ghanshyam , Talele Chitrali , Talele Dipali , Seth Avinsh Kumar
Published: January 2024

Light-sensitive liposomes have emerged as a promising platform for drug delivery, offering
the potential for precise control over drug release and targeted therapy. These lipid-based nanoparticles
possess photoresponsive properties, allowing them to undergo structural changes or release
therapeutic payloads upon exposure to specific wavelengths of light. This review presents an overview
of the design principles, fabrication methods, and applications of light-sensitive liposomes in
drug delivery. Further, this article also discusses the incorporation of light-sensitive moieties, such as
azobenzene, spiropyran, and diarylethene, into liposomal structures, enabling spatiotemporal control
over drug release. The utilization of photosensitizers and imaging agents to enhance the functionality
and versatility of light-sensitive liposomes is also highlighted. Finally, the recent advances, challenges,
and future directions in the field, emphasizing the potential for these innovative nanocarriers to
revolutionize targeted therapeutics, are also discussed.
Structural, Morphological, Spectroscopic, and Dielectric Properties of
Ca-Mg Nanoferrites for High-frequency Applications
Authors: Kumari Sonam , Thakur Atul , Thakur Preeti
Published: January 2024

Introduction::

Ca-Mg nanoferrites of composition Ca0.5Mg0.5Fe2O4 were
synthesized by wet chemical citrate precursor approach.

Methods::

The prepared nanoparticles were characterized by an “X-ray diffractometer,
Scanning electron microscopy, Diffused reflectance spectroscopy, and Impedance
analyzer”. In the XRD pattern, the most intense reflection was observed from the
(311) peak that corresponds to the cubic spinel phase of the prepared ferrite.

Results::

The average size of all crystallites was calculated to be 19 nm. The sample's
porosity was found to be 61%. In the SEM micrograph, uniformity in the size of the
particles was detected with some agglomeration. The calculated energy band gap
(1.91eV) reveals the semiconducting nature of the prepared material.

Conclusion::

The high value of the real part of the dielectric constant (290) and the
low value of loss tangent (0.17) reveals that the synthesized material can be useful in
magnetic cores, microwave components, and other high-frequency applications.
Antiviral Medications: Unravelling their Significance in Context to
COVID-19
Authors: Chalotra Rishabh , Singh Amanjot , Chib Shivani , Gautam Swati , Amanat Muhammed , Chaudhary Kakul , Kumar Manish , Singh Randhir
Published: January 2024

Viruses represent a significant health menace due to their rapid transmissibility and
potential to cause worldwide pandemics, resulting in substantial loss of human life. Antiviral agents
play a pivotal role in mitigating the impact of viral infections. Nonetheless, treating viral infections is
a multifaceted process due to the inherent characteristics of viruses, such as their capacity to undergo
mutations and rapid evolution. Consequently, the effectiveness of current antiviral therapies can be
impeded. This review encompasses the diverse manners in which viruses, emphasizing COVID-19,
affect the human body and elucidates the challenges encountered in formulating efficacious antiviral
treatments. Moreover, the limitations of conventional antiviral therapies are underscored.
Additionally, a comprehensive compendium of 41 antiviral drugs is presented, detailing their
mechanisms of action and routes of administration. Subsequently, the discussion includes 9 drugs
repurposed for treating COVID-19, delineating their primary use as well as any accompanying side
effects. In conclusion, while antiviral drugs remain pivotal in the battle against viral infections, the
obstacles associated with their development and usage warrant careful consideration. Ongoing
research is imperative to devise more potent and less toxic antiviral interventions against COVID-19
infection.
Tailoring Ti3C2Tx MXene Flake Sizes for Modified Electrochemical
Performance: A Top-down Approach
Authors: Fan Yuchao , Mei Xu , Ye Li , Tian Qingyong , Zhang Renqi , Zhang Yingjiu , Li Xinjian
Published: January 2024

Introduction:

Two-dimensional (2D) materials, such as MXene (Ti3C2Tx), have
garnered extensive attention in recent years due to their exceptional performance across various
domains. The flake size of Ti3C2Tx notably influences its specific surface area, a pivotal factor
in interfacial interactions within electrochemistry.

Method:

Presently, modifying the flake size of bulk Ti3C2Tx typically involves complex and
costly processes, like ultrasonic treatment and isolation. Leveraging the specific preparation
principle of MXenes, which involves etching the A layers in precursor MAX phases, a topdown
strategy for producing Ti3C2Tx flakes of desired sizes, has been proposed in this work. In
this approach, precursor Ti3AlC2 particles undergo ball-milling to adjust their size.

Result:

Through this innovative strategy, dispersions of Ti3C2Tx flakes with varying average
lateral sizes are generated, enabling an investigation into the impact of lateral size on the electrochemical
properties of Ti3C2Tx flakes. By controlling the ball milling time for Ti3AlC2 powders,
the resulting average sizes of Ti3C2Tx (0, 2, 4) are 6.34 μm, 2.16 μm, and 0.96 μm, respectively.
Particularly, the Ti3C2Tx (2) electrode, composed of 2.16 μm sheets, demonstrates remarkable
performance metrics. It exhibits a high areal capacitance of 845.0 mF/cm2 at a scan
rate of 5 mV/s, along with a gravimetric capacitance of 244.0 F/g at a current density of 1 A/g.

Conclusion:

This study presents a facile method to enable mass production of Ti3C2Tx with
sheets of varying sizes, addressing both small and large dimensions.
FEN BİLGİSİ ÖĞRETMEN ADAYLARININ FARK ETME BECERİLERİNİN İNCELENMESİ
Authors: İnaltun Hüseyin
Published: January 2024

Fen bilgisi öğretmenlerinin sürekli değişim içerisindeki karmaşık sınıf ortamlarında öğrencilerin fen ile ilgili düşüncelerine katılım göstermeleri, bu düşüncelerin altında yatan gerekçeleri ortaya çıkarmak için analiz etmeleri ve analiz sonuçlarına göre öğretimlerini planlamaları gerekmektedir. Fark etme becerisi olarak isimlendirilen bu uygulamalar öğrencilerin fen öğrenmeleri açısından kritik öneme sahiptir. Bu sebeple fen bilgisi öğretmen adaylarının bu becerilerini geliştirmeleri için gerekli desteğin sağlanması gerekmektedir. Ancak bu desteğin etkili bir şekilde sağlanabilmesi için ilk olarak fen bilgisi öğretmen adaylarının fark etme becerilerinin mevcut durumları keşfedilmelidir. Bu sebeple bu çalışmada temel nitel araştırma deseni kullanılarak Türkiye’de bir devlet üniversitesinde öğrenim görmekte olan 11 dördüncü sınıf fen bilgisi öğretmen adayının fark etme becerileri araştırılmıştır. Öğretmen adaylarının hazırladıkları ders planları, staj uygulamaları sırasında elde ettikleri öğrenci ürünleri ve açık uçlu sorulara verdikleri yanıtlar aracılığıyla elde edilen veriler içerik analiziyle incelenmiştir. Çalışmanın bulguları öğretmen adaylarının öğrencilerin ilgili fen konusunda anlayışlarını yansıttıklarını düşündükleri ürünlere genellikle öğrencilerin derste anlatılanları hatırlamalarını gerektiren etkinlikler aracılığıyla ulaştıklarını göstermiştir. Ayrıca bulgular öğretmen adaylarının bu ürünlerde çoğunlukla öğrencilerin fen ile ilgili düşünceleri yerine ürünlerin doğruluğu veya yanlışlığına odaklandıklarını ortaya çıkarmıştır. Son olarak bulgular öğretmen adaylarının öğrenci ürünlerini yüzeysel olarak öğrenmiş/öğrenmemiş perspektifinden analiz ettiklerini ve öğrenci ürünlerinin altında yatan gerekçeleri ortaya çıkarmaya yönelik girişimlerde bulunmadıklarını göstermiştir.
ERGENLERDE KARİYER KAYGISININ MÜKEMMELİYETÇİLİK VE ÇEŞİTLİ DEMOGRAFİK DEĞİŞKENLERCE YORDANABİLİRLİĞİNİN İNCELENMESİ
Authors: Cırcır Osman , Uzun Kıvanç , Tagay Ozlem , Gönültaş Osman
Published: January 2024

Bu çalışmanın amacı, mükemmeliyetçilik, cinsiyet, algılanan sosyoekonomik düzey ve algılanan akademik başarı değişkenlerinin ergenlerin yaşadıkları kariyer kaygısını ne düzeyde yordadığını belirlenmektir. Buradan hareketle, değişkenlerin arasında beklenen muhtemel ilişkiyi belirlemek için ilişkisel tarama modelinden yararlanılmıştır. Çalışma grubunun oluşturulması ise uygun örneklemeyle yapılmıştır. Araştırmacıların hazırladığı uygulama formu, Türkiye’nin *** ilinde bulunan ve ergenlik döneminde olan 352 katılımcıya uygulanmıştır. Araştırmanın verileri, araştırmacılarca hazırlanan ve kişisel bilgilerin sorulduğu bir form, Kariyer Kaygısı Ölçeği ve Üstün Yetenekli Ortaokul Öğrencileri için Psiko-Sosyal Özellikler Ölçeği’nin mükemmeliyetçilik alt boyutu kullanılarak toplanmıştır. Elde edilen verilerin analiz işlemlerinde, çoklu doğrusal regresyon analizinden yararlanılmıştır. Araştırma kapsamında ulaşılan sonuçlar, mükemmeliyetçi olmanın, kadın olmanın, orta düzeyde sosyoekonomik duruma sahip olmanın ve düşük düzeyde akademik başarıya sahip olmanın ergenlerdeki kariyer kaygısı ile pozitif yönde; erkek olmanın, yüksek düzeyde sosyoekonomik duruma sahip olmanın ve yüksek düzeyde akademik başarıya sahip olmanın ise ergenlerdeki kariyer kaygısı ile negatif yönde ilişkili ve anlamlı birer yordayıcı oldukları şeklindedir. İlgili alanyazından destek alınarak, ulaşılan sonuçların tartışması yapılmıştır ve bu tartışmadan hareketle gelecekte yapılması planlanan araştırmalara öneriler sunulmuştur.
OKUL ÖNCESİ DÖNEM RESİMLİ ÇOCUK KİTAPLARINA YÖNELİK BİR İNCELEME: GECE KORKULARI
Authors: Yalman Feyza , Ceylan Şehnaz
Published: January 2024

Erken çocukluk döneminde çocuklarda görülen yaygın korkulardan biri gece korkularıdır. Gece korkuları, özellikle 4-6 yaş aralığında görülmekle birlikte gerekli destek sağlanmadığında uzun yıllar devam ederek fobiye dönüşebilmektedir. Gece korkuları, heterojen bir yapıya sahiptir ve kendi içinde farklı şekilleri bulunmaktadır. Bunlar: güvenlikle ilgili korku, ayrılma korkusu, hayali yaratıklardan korkma, kabuslardan korkma ve karanlık korkusudur. Kitaplar, erken çocukluk döneminde çocukların duygularını ifade etme, temel bilgi ve becerileri kazanmada en etkili araçlardandır. Bu dönemde, çocukların günlük hayatta yaşadıkları duygular ve karşılaştıkları durumların kitaplarla ele alınması, bu durumların üstesinden gelmelerinde çocuklara yardımcı olmaktadır. Bu çalışmanın amacı, Türkiye’deki gece korkusunu ele alan kitapları incelemek ve kitapların içerik özelliklerini çeşitli boyutlarla ortaya koymaktır. Veriler içerik analizi yöntemiyle incelenmiştir. İnceleme sonucunda Türkiye’deki gece korkusu temalı kitapların büyük oranda çeviri kitap olduğu görülmüştür. Kitaplarda korku kaynaklarının büyük oranda “karanlık”, “canavar” ve “sesler” olarak işlendiği, korku ve/veya kaynağının çoğunlukla karanlık/gölge ve yaratık/canavar şeklinde resmedildiği görülmüştür. Kitaplarda korkuyla baş etme stratejileri çoğunlukla “korkunun gerçek kaynağını bulmak” ve “biriyle konuşmak”tır. Kitapların çoğunda korku problemi çözüme kavuşmuştur. Kitaplarda korkuyla baş etmede yardımcı karakterin çoğunlukla anne-baba olduğu görülmüştür.
Analisa Tingkat Bahaya Erosi Berbasis Sistem Informasi Geografis (SIG) Pada SubDAS Ngasinan Kabupaten Trenggalek Jawa Timur
Authors: Handoko Shubhananda Aulia , Andawayanti Ussy , Dermawan Very
Published: January 2024

Perubahan fungsi tata guna lahan pada subDAS Ngasinan merupakan penyebab utama terjadinya banjir serta longsor pada beberapa daerah ketika hujan besar menerjang. Perubahan tata guna lahan menimbulkan erosi yang diakibatkan limpasan pada daerah tersebut meningkat. Studi ini bertujuan untuk mengetahui besar laju erosi, kondisi tingkat bahaya erosi, dan memberikan saran berupa arahan konservasi lahan yang sesuai dengan kondisi subDAS Ngasinan. Analisa dilakukan menggunakan aplikasi ArcGIS dengan pendekata model ArcSWAT. Pemodelan aplikasi ArcSWAT menggunakan metode MUSLE untuk mendapatkan nilai erosi, sedimen, hingga limpasan. Hasil analisa pemodelan didapatkan nilai rerata laju erosi sebesar 34, 796 ton/ha/tahun atau 2,899 mm/tahun serta rerata sedimen 24,322 ton/ha/tahun. Berdasarkan hasil tersebut didapatkan nilai IBE Rendah (Potensial Kritis) 30 Ha, IBE Sedang (Semi Kritis) 18722 Ha, dan IBE Tinggi (Kritis) 37270 Ha. Berdasarkan hasil tersebut dapat disimpulkan bahwa kondisi DAS Ngasinan memerlukan sebuah arahan konservasi. Usaha konservasi yang akan dilakukan menggunakan metode vegetatif sesuai dengan arahan Balai Rehabilitasi dan Konservasi Tanah (BRLKT).
A Survey of Speech-Language Pathologists’ Knowledge and Perception About Their Role in Providing Dysphagia Services in India
Authors: Devan Rekha , MK Niharika
Published: January 2024

Purpose: Speech-Language Pathologists (SLPs) are frequently involved in dysphagia services including identification, assessment, diagnosis, and rehabilitation. Understanding of SLPs’ role in dysphagia care has evolved drastically in India over the last decade; however, research and advocacy are still in emerging status. In order to refine dysphagia practice patterns in India, we should understand the current standards. Thus, the present study was conceived to investigate SLPs’ knowledge and perception about their role in providing dysphagia services in India.Methods: A cross-sectional online survey research design was employed. The survey questionnaire comprised of four sections that evaluated SLPs’ demographic characteristics, exposure to dysphagia services, self-perception about their role in the dysphagia rehabilitation team, and knowledge related to assessment and management of individuals with dysphagia. The obtained responses were stored in Google forms and were further analyzed in terms of percentage.Results: A total of 269 SLPs responded to the survey and 59% of the respondent SLPs practicing in India were rendering dysphagia services. Although a majority of the SLPs had adequate knowledge and were aware of their role in the interdisciplinary dysphagia rehabilitation, they lacked opportunities to be a part of the team.Conclusion: The survey clearly identified the trend and issues in dysphagia service delivery by SLPs in the Indian scenario by evaluating their knowledge and skills fundamental to the assessment and management of individuals with dysphagia. This further necessitates a re-examination of the role of SLPs in providing dysphagia services in India in view of establishing standard guidelines and practice patterns.
Assessment of DP Threshold and its Test–Retest Reliability in Normal Hearing Individuals
Authors: Neupane Anuj Kumar , Bheda Kalpesh , Mehta Gunjan
Published: January 2024

Purpose: Distortion Product (DP) threshold test has been recently introduced as a clinical tool that provides frequency specific quantitative information on hearing sensitivity in dB HL. However, due to the dearth of literature in determining its degree of reliability, the extent of confidence in the test results has not been estimated. Therefore, the present study aimed at establishing the normative of DP threshold values across test frequencies in normal hearing individuals and check for its test-retest reliability.Methods: Purposive sampling was utilized in the study wherein fifty normal hearing individuals in the age range of 18 to 30 years (x̅=24, σ=2.1) were considered. DP threshold test was carried out across test frequencies from 1 kHz to 8 kHz in measurement window of 50 dB HL and was re-examined after 15 days.Results: The range of DP threshold level was -5 to 20 dB HL in right ear and -5 to 25 dB HL in left ear across the test frequencies. It was found to have the mean difference ranging -0.02 to 1.06 dB HL across test frequencies between the two sessions. Non-parametric Wilcoxon Signed Ranks test was performed to assess test-retest reliability which revealed no statistically significant difference for both ears (p>0.05).Conclusions: Hence, the current study presents normative of DP threshold test along with variance, beyond which the fluctuations in outer hair cell functioning can be expected to have occurred. Moreover, it is found to have good test retest reliability between the two sessions suggesting good potentiality of the test in assessing outer hair cells functioning.
Factors that Influenced Lndian Wtudents to Choose the Career of Audiology and Speech Language Pathology: A Questionnaire Based Study
Authors: Biju Anitta , Kalaiah Mohan Kumar , Shastri Usha
Published: January 2024

Purpose: Studies have identified various aspects that influenced the career choice among Audiology and Speech Language Pathology (ASLP) students/professionals in different countries. The factors influencing the choice of career as an ASLP in the Indian context have not been explored. If the predisposing aspects are identified, action can be taken to motivate the prospective students to become an ASLP. Hence, the present study aimed to identify the factors that influenced Indian students to choose ASLP as an option for higher education.Methods: A 20-item questionnaire was developed, validated, and distributed via emails/social media platforms to students pursuing ASLP. A total of 380 undergraduate ASLP students studying at various Speech and Hearing colleges in India responded to the questionnaire.Results: Chi-square association between few demographic details and factors were checked with ASLP as first career choice. Results of the study showed that the participants who had not applied to any other program, had the desire to work in a helping profession, had an experience with an individual with communication disorder, and had an influence from the academic curriculum had a greater chance of having ASLP as the first career choice.Conclusion: Findings of the present study showed similarities and differences in the factors that influence choosing career of ASLP among students in India in comparison to other countries. This study also identified the key factors that could promote the career of ASLP in India, to improve its visibility to young college aspirants. The need for a career counselling is implied by the findings of this investigation.
A Comparative Study on Visual Attention, Verbal Engagement and Parental Behaviors During Shared Book Reading Using Scripted and Unscripted Story Books for Children with Autism Spectrum Disorder
Authors: Mohan P Veena , Ullas Sahra , Biju Aksa Susan
Published: January 2024

Purpose: Shared book reading is nowadays considered as an important early language stimulation technique in the field of speech language pathology which encourages parent-child bonding and creates a conducive environment for language development. The parent-child interaction is important for a child with Autism Spectrum Disorder. This interaction along with adequate and contingent parental responses fosters early language development in children. Language-related parent behaviors promote children’s oral language skills by not only exposing the child to book-related vocabulary (e.g., labeling pictures, explaining word meanings, and linking words to everyday events), but also through explicit teaching of meaning-related skills related to the overall structure of the story (i.e., story grammar). Print-related SBR behaviors draw the child’s attention to print-related features of the book, for example, letter names and sounds.Methods: To better understand the relationship between children’s visual attention, verbal engagement and parent shared book reading behaviors during shared book reading tasks, this study included 10 preschoolers on the Autism Spectrum and their parents sharing an unfamiliar storybook including which are scripted and unscripted. Videos of the shared book reading interactions were transcribed and coded for visual attention, verbal engagement and parent behaviors using observational coding schemes. The frequency of visual attention, verbal engagement and parental SBR behaviors were compared between the scripted and unscripted story books using statistical tests-Wilcoxon signed rank test and Fisher’s Exact test.Results: Result reveals that there was no statistically significant difference between frequency of visual attention during unscripted story books and scripted books. Parental behaviors parameters pertaining to shared book reading were analyzed and found a significant difference in usage of book language is greater for scripted story books compared to unscripted books.Conclusions: The key findings shows the type of book (scripted or unscripted) have a significant impact and its contribution to the intervention of children with Autism Spectrum Disorder. Parental SBR behaviors can in turn contribute to the development of childhood language and preliteracy skills.
Clinical Profiling of Stuttering Characteristics in a Speech Clinic of a Tertiary care Hospital- a Retrospective Study of the Decennial Trend
Authors: Kavya S. , Veena Kadiyali D. , Bellur Rajashekhar
Published: January 2024

Purpose: Stuttering is a speech disorder, which affects the smooth flow of speech with a worldwide prevalence rate of about 1%. Reports on the estimation of stuttering prevalence across all age groups based on various influential factors are limited. Clinical profiling of stuttering characteristics in a speech clinic of a tertiary care hospital using retrospective data of 10 years.Methods: The decennial trend of stuttering between January 2010 and December 2019 with a complete enumeration of stuttering cases across all ages reported in the tertiary care clinic were analysed retrospectively for various factors such as primary and secondary features, and associated deficits.Results: Overall prevalence rate over a 10-year period was estimated to be 4.7%. Descriptive data on characteristics and influential factors related to the occurrence of stuttering were profiled.Conclusions: This study can be used to understand the decadal trends in stuttering traits. Information about contributing factors can help take steps to prevent risk factors for stuttering. The findings of this study will allow SLPs to understand the need for better documentation and intervention strategies for this population.
Effective Duration of Auditory Training for Speech Perception in Hearing-Impaired Listeners: A Systematic Review and Meta-Analysis
Authors: Chae Se Rim , Bahng Junghwa
Published: January 2024

Purpose: The purpose of this study was to conduct a meta-analysis to determine the effective duration of auditory training for hearing aid users and cochlear implant users and to identify factors that influence the effectiveness of auditory training.Methods: We searched literature published from January 1996 to August 2021 in Pubmed, Web of Science, Embase and Cochrane Library. A total of 24 studies that met the selection criteria were systematically reviewed and analyzed through meta-analysis. Standardized mean differences and 95% confidence intervals were calculated.Results: The overall meta-analysis results for auditory training showed an effect size of -0.833, and the effect size was larger in “more than 600 minutes of auditory training” compared to “less than 600 minutes”. There was no statistically significant difference in effect size during follow-up observation after the completion of auditory training, with an effect size of 0.057 (95% CI: -0.113-0.112, p=0.988). Subgroup analysis showed that the effect size was larger in the “children” group than in the “adult” group. The effect size of auditory training was larger when the auditory training and measurement conditions were the same.Conclusions: Auditory training can improve speech perception in individuals wearing HA and/or CI, and the training effect was shown to be maintained even after the completion of auditory training. In addition, it was found that the longer the duration of auditory training (more than 10 hours), the greater the training effect.
Remote Testing of Adult Neurogenic Tests: Implications and Recommendations for Speech-Language Pathologists
Authors: Burda Angela , Axt Carrie , Balk Samantha , Bleile Zoe , Fahey Madilyn , Freeman Paul Kort , Hogelucht Heather , Schultz Paeten , Shaffer Kamryn , Wright Kara
Published: January 2024

Purpose: One purpose of this preliminary case report was to document the challenges that can arise when giving adult neurogenic tests via telepractice. Another purpose was to develop recommendations on adaptations that can be made when speech-language pathologists give the tests employed in this report. Though one test was adapted by its authors to be given remotely, the other two tests have little or no published adaptations regarding remote administration.Methods: A 33 year old female and a 51 year old male, both of whom have acquired neurogenic communicative disorders, were given the Apraxia Battery for Adults-2nd edition, the Ross Information Processing Assessment-2nd edition, and the Quick Aphasia Battery-Remote via telepractice across 2-3 sessions per participant. The female participant used an iPad during remote testing, while the male participant used a Chromebook.Results: All three tests had some challenges when given remotely. Though slight technical issues were encountered, the research team needed to make various test adaptations, such as putting pictures into a Google presentation so that patients could adequately see the target picture. In other instances, wording to questions were changed slightly while still retaining the general integrity of the original item.Conclusions: Recommended adaptations to the three tests used in this study are included. Though issues may arise during telepractice, these suggestions should aid clinicians who want to use these tests with their telepractice clients.
Analysis of Errors Following SCVTr Treatment: An Indicator for Improved Lexical Retrieval Abilities in Persons with Aphasia
Authors: Puttanna Deepak , Goswami Sathyapal Puri , Swamy Akshaya
Published: January 2024

Purpose: Error analysis technique aids in understanding the psycholinguistic mechanisms associated with word retrieval. In addition to the linguistic test scores, if authors document the change in errors following treatment it may give better insight into the prognosis of PWAs. Despite the significance of error analysis, most of the study results elucidate the improvement merely in assessing the accuracy of naming skills. Thus, the present study was designed to assess the error patterns following treatment.Methods: A total of 11 PWAs (fluent and non-fluent aphasia) were enrolled for the study, these participant’s average age was 38.72 years (Range=24-64, SD=11.97). SCVTr treatment was rendered; in this treatment, PWAs were presented with 10 targeted verbs with a range of minimal (broad cues) and maximal cues (narrower cues) based on the success of the retrieval minimal to maximal cues were presented. The verbatim of trained and untrained stimuli (probes) of pre-treatment phase, post-treatment phase, and follow-up phase were subjected to error analysis using Edmonds and Babb (2011) protocol.Conclusions: The error patterns of individual participants across pre and post-treatment phases showed alleviated scores in the post-treatment phase among all the participants. Furthermore, all the participants exhibited almost identical error score patterns in the follow-up phase as in the post-treatment phase. The error analysis technique is the most powerful tool to track the changes at the psycholinguistic level.
Reinventing Speech-Language Pathologists’ Approach to Psychosocial Barriers and Dysphagia Management
Authors: Tarpley Ashley , Paramby Towino
Published: January 2024

Purpose: Speech-language pathologists (SLPs) are responsible for addressing psychosocial factors, such as fear, embarrassment, disgust, anxiety, and depression, as they relate to dysphagia to ensure effective symptom management; however, SLP understanding of such responsibility remains largely unexplored.Methods: This study was conducted by sharing a survey with SLPs to 1) analyze their awareness and acknowledgment of psychosocial factors experienced by adult clients with dysphagia, and 2) pinpoint whether a need for broader education and awareness of psychosocial symptoms experienced by adults with dysphagia exists in the field of communication sciences and disorders. Qualitative and quantitative data analysis were performed to analyze the survey findings.Results: Findings regarding SLP education demonstrate that the majority of SLPs did not receive education on the topic of psychosocial factors and their relation to adults with dysphagia. The majority of SLPs actively screen their adult clients with dysphagia for psychosocial symptoms (62.96%), and the most common formal screening tool is the Eating Assessment Tool (47.17%). SLP respondents show a majority preference for increased access to information and education regarding psychosocial symptoms as they relate to adults with dysphagia (92.45%).Conclusions: The study revealed a general lack of education provided to SLPs by higher education programs, differing preferences in screening tools utilized by SLPs, and a shared desire among SLPs to have increased access to information regarding their professional role and acknowledgement of psychosocial barriers adults with dysphagia may experience.
A Study on Media Literacy Use in School-Age Children with Language Disorder
Authors: Chang Hyun-Jin , Lee Eun Kyoung
Published: January 2024

They should be provided with new means of communication that emerge with the changing times. They should be able to recognize the advantages of the features of different media so that they can use the media usefully. The author believes that the effective and appropriate use of media literacy for elementary school students with disabilities will result in a positive impact. Therefore, this study aims to analyze the actual level of media literacy among School-age language disorder with disabilities and explore ways to promote it in a therapeutic aspect. Of the 40 people, 4 who did not respond appropriately were excluded, resulting in 36 people. In order to find out the status of media literacy use by speech rehabilitation workers currently working in language clinical sites, an online survey using Google Docs and a paper questionnaire were administered to the subjects. For the purpose of the study, ‘A survey on the use of media literacy by school-age children with language disorder’, the purpose of this study, the direction of data use, and how to complete the questionnaire were explained. We investigated the status and status of media use among school-age children with language disorder. The media used by the target children for more than 3 hours were games, animation, and Youtube. Among media outlets, it can be seen that SNS usage time is less than 2hours. And it was found that the target children were using all media, including TV, Game, Animation, Youtube, SNS, Movie/Drama, and Internet portal search. School-age children with language disorder had excellent use skills related to media devices, such as searching task-related keywords, grasping various contents, and finding task information. On the other hand, the subjects showed a low ability to use online information to evaluate its rationality and fairness. Lastly, all of the target children had low scores on questions related to media production ability. In particular, by understanding the current status of school-age media literacy content, it will be possible to identify the advantages of the characteristics of various media and apply them usefully in treatment.
Enhancing Leadership and Professionals of Speech-Language Pathology: Perspectives of Korean SLPs on Supervisor Requirements and Supervisory Training Courses
Authors: Choi Seong Hee , Lee Eun Kyoung
Published: January 2024

Purpose: Clinical supervision is a dynamic and collaborative ongoing process in speech-language pathology. This study aims to prepare the supervisor certification standards of the Korean Association for Speech-Language Pathologists (KSLP) and the contents of the professional development courses.Methods: A total of 611 Korean speech-language pathologists (SLPs) (52 males, 559 females) completed the Google online survey regarding their perception and demand on the qualifications and core competencies of supervisors and supervisor training courses to develop SLP’s leadership and professional competencies.Results: 74% of respondents believed that a supervisor training courses was necessary to strengthen the professionalism and competence of SLPs, and 79% perceived they were willing to receive clinical supervisor training. Regarding supervisor qualification requirements, 53% answered that the clinical experience required for supervisor qualification was more than 10 years; the highest response rate was 10 hours (53%) of introductory courses and 10 hours (62%) of advanced courses. Respondents felt that an interval every two years was most appropriate (49%) for professional development requirements. The fundamental concepts of knowledge, skills, core competencies, and supervision that supervisors should have were also addressed and discussed.Conclusions: The current survey identified common perceptions and strong demands for a systematic supervisor training framework. The results derived from supervisees’ high demand and awareness can serve as a starting point for developing standards for the supervisee-centered supervisor system of speech-language pathology in Korea.