bluuebunny/crossref_metadata_2025 huggingface dataset:
Indigenous-Environmental-Autonomy-in-Aotearoa-new-Zealand
Authors: Forster Margaret
Published: May 2018

British colonization of Aotearoa New Zealand diminished the influence of the tribal territory on Indigenous autonomy, identity and belonging. Yet land is still key to securing Indigenous futures. This paper explores the reassertion of Indigenous autonomy over the environment. A governmentality critique is used to explore efforts to embed indigeneity into environmental politics. As part of this critique three examples of Indigenous environmental autonomy are provided that show how Māori are asserting greater control over the tribal territory, particularly natural resources. I argue that resistance has been critical for the re-emergence of Māori autonomy over the environment, creating greater opportunities for assertions of local authority and the customary practice of kaitiakitanga (a Māori environmental ethic). Although there is still much to achieve in this space, Māori are now in a stronger position to resist ongoing colonization of the landscape and engage with the state around resource management of natural resources.
Rehabilitación hidrológica de barrios a través de sistemas urbanos de drenaje sostenible = Hydrological rehabilitation of neighbourhoods using sustainable urban drainage systems
Authors: Calama-González Carmen , Calama-Rodriguez Jose María , Cañas-Palop Cecilia
Published: May 2018

ResumenEste artículo es una síntesis del proyecto de investigación realizado en la Universidad de Sevilla para diseñar un modelo de análisis que permita la comprobación de la viabilidad técnica y socioeconómica de los proyectos de rehabilitación hidrológica de barrios urbanos, mediante la construcción de infraestructuras de drenaje sostenibles. El modelo propuesto presenta novedades significativas con respecto a los empleados tradicionalmente en los sistemas urbanos de drenaje sostenible. En primer lugar, se parte de la base de la realización de análisis previos que permitan comprobar la posibilidad de recuperación del agua de lluvia para que, tras sencillos tratamientos para eliminar sus posibles contaminantes, pueda ser usada en labores urbanas del barrio que no requieren agua de calidad. Además, al plantearse como un proyecto cuyo objetivo es “la rehabilitación hidrológica” de un barrio urbano habitado, se contempla medidas clave para conseguir la interacción con los agentes sociales que intervendrán en la gestión local del ciclo del agua, incluyendo medidas sociales y educativas relacionadas con el uso del agua. La finalidad del modelo es aportar los suficientes datos, tanto relacionados con las características del lugar como con la calidad del agua, para poder diseñar unos Sistemas Urbanos de Drenaje Sostenible que sean adecuados.AbstractThis paper summarizes a research project conducted in the University of Seville, in order to design an analysis model that allows the assessment of technical and socio-economic viability of hydrological rehabilitation projects in urban neighbourhoods, through the construction of sustainable drainage infrastructures. The model proposed presents significant developments when compared with the ones traditionally used in sustainable urban drainage systems. On the one hand, the possibility of recovering rainwater with simple treatments, eliminating potential contaminants, has been verified previously, testing water for urban purposes with no quality requirements. Moreover, since the main objective of this project is the “hydrological rehabilitation” of an inhabited neighbourhood, the interaction with social agents is a key factor that must be considered for a more appropriate local management of the water cycle, thus social and educational measurements related to the use of water have been included. The aim of this model is to present sufficient data, both referred to the water quality and hydrological conditions of the neighborhood, in order to design adequate Sustainable Drainage Urban Systems.
Moderate the MAOA-L Allele Expression with CRISPR/Cas9 System
Authors: Nelwan Martin L.
Published: May 2018

Antisocial behavior is a behavior disorder inherited according to the inheritance of X-linked chromosome. This disorder derives from mutations in the MAOA gene. One of the mutations results in the MAOA-L allele activity. The MAOA-L allele activity can cause antisocial behavior in both healthy and unhealthy people. Antisocial behavior from healthy males can originate from maltreatment during childhood. Currently, MAOA inhibitor can reverse antisocial behavior to normal behavior in animal models. However, this disorder cannot be treated permanently; to treat it permanently in the future, technologies such as CRISPR/Cas9, iPSCs and ssODN are required. These technologies have succeeded to correct erroneous segments in the F8 gene and F9 gene. Both genes occupy the X chromosome. The MAOA gene also occupies the X chromosome. Therefore, it is reasonable to state that CRISPR/Cas9 and iPSCs technique for instance can be beneficial tools to edit the MAOA gene to treat antisocial behavior. CRISPR/Cas9 can be used in combination with iPSCs or ssODN for instance. This combination can greatly help the permanent healing of antisocial behavioral disorders.
Relative Abundance of Insect Predators Varies among Rice Plots as a Function of Surrounding Landscape
Authors: ALI Md. Panna , Kabir Mir Md. Moniruzzaman , Haque Sheikh Shamiul , Hashem Abeer , Abd_Allah Elsayed Fathi
Published: May 2018

Relationships among the population abundance of four predator groups for rice insect pests, namely: carabid beetles, staphylinid beetles, green mirid bugs, and spiders in three landscape categories were evaluated. Both rice plots and the associated bund margins of these rice plots found among three Bangladesh landscape categories were sampled by sweep net. The results revealed that the abundance significantly varied across landscapes. The rice landscape of one location harbored higher numbers of a specific predator than other location in other regions of Bangladesh. The results also showed a dependency on the width of the rice bund margins of the rice plots, where spiders populations increased with increased bund widths, but the population abundance of these predators did not depend on the diversity of the number of weed species found on the rice bund margins. The relative abundance of predator populations also significantly differed among the three landscapes, with the green mirid bug having the highest number among the four predators. This study indicates that predators of rice insect pests are highly landscape specific. In order to design integrated pest management systems for different Bangladeshi rice production locales, considerations unique to the characteristics of each locale are necessary. Preliminary efforts to apply variography analyses to the RED spectral band of LANDSAT 8 imagery from December 2016 are presented as first step toward learning a suite of methods which describe useful local characteristics affecting rice pest predators.
Boron Monochalcogenides; Stable and Strong Two-Dimensional Wide Band-Gap Semiconductors
Authors: Mortazavi Bohayra , Rabczuk Timon
Published: May 2018

In this short communication, we conducted first-principles calculations to explore the stability of boron monochalcogenides (BX, X=S, Se or Te), as a new class of two-dimensional (2D) materials. We predicted BX monolayers with two different atomic stacking sequences of ABBA and ABBC, referred in this work to 2H and 1T, respectively. Analysis of phonon dispersions confirm the dynamical stability of BX nanosheets with the both 2H and 1T atomic lattices. Ab-initio molecular dynamics simulations reveal the outstanding thermal stability of all predicted monolayers at high temperatures over 1500 K. BX structures were found to exhibit high elastic modulus and tensile strengths. It was found that BS and BTe nanosheets can show high stretchability, comparable to that of the graphene. It was found that all predicted monolayers exhibit semiconducting electronic character, in which 2H structures present lower band-gaps as compared with 1T lattices. The band-gap values were found to decrease from BS to BTe. According to the HSE06 results, 1T-BS and 2H-BTe show respectively, the maximum (4.0 eV) and minimum (2.06 eV) electronic band-gaps. This investigation introduces boron monochalcogenides as a novel class of 2D semiconductors with remarkable thermal, dynamical and mechanical stability.
In Vitro Seedlings of Eustoma grandiflorum in Response to LED Light in an Acclimation Environment
Authors: Roni Md Zohurul Kadir , Islam Md Saiful , Shimasaki Kazuhiko
Published: May 2018

Transferring in vitro-cultured Eustoma seedlings to an ex vitro condition (acclimation) is a big challenge that may expose the seedlings to biotic and abiotic stresses, and affect the internal and external structure of the plants. In addition, in vitro-cultured seedlings of Eustoma are difficult to handle and phenotype and physiological traits such as survival and rosette rate may have altered in the acclimation stage. Therefore, the present study aims to examine the effects of blue, red, and white LED light on the growth and development ex vitro of in vitro-cultured seedlings of Eustoma. The results showed that blue LEDs resulted in greater plant height, internode length, and leaf number, increased upper and lower fresh biomass, and higher chlorophyll content compared with treatment by the other LED lights. Higher stomatal density on the abaxial leaf surface was also observed in the blue LED-treated plants, which also showed a higher survival rate and lower rosette rate. In contrast, the white LED-treated plants had the highest leaf width and internode diameter. Acclimation of the Eustoma plants ex vitro suggests that a combination of blue and white LEDs may be advantageous for better growth and development for large-scale production in a controlled environment.
FMSP-Nanoparticles Induced Cell Death on Human Breast Adenocarcinoma Cell Line (MCF-7 cells): Morphometric Analysis
Authors: Khan Firdos Alam , Akhtar Sultan , Almofty Sarah Ameen , Almohazey Dana , Alomari Munthar
Published: May 2018

Breast cancer treatment mostly revolved around radiation therapy and surgical interventions, these treatments doesn’t provide satisfactory relief to the patients and carry unmanageable side-effects. Nanomaterials show promising results in treating cancer cells and have many advantages such as high biocompatibility, bioavailability and effective therapeutic capabilities. Interestingly, fluorescent magnetic nanoparticles have been used in many biological and diagnostic applications, but there is no report of use of fluorescent magnetic submicronic polymer nanoparticles (FMSP-nanoparticles) in the treatment of human breast cancer cells. In the present study, we have tested the effect FMSP-nanoparticles on human breast cancer cells (MCF-7). We have tested different concentrations (1.25µg/1mL, 12.5µg/mL and 50µg/1mL) of FMSP-nanoparticles in MCF-7 cells and evaluated the nanoparticles response morphometrically. Our results revealed that FMSP-nanoparticles produced a concentration dependent effect on the cancer cells, dose of 1.25µg/mL produced no significant effect on the cancer cell morphology and cell death, whereas dosages of 12.5µg/mL and 50µg/mL respectively showed significant nuclear augmentation, disintegration, chromatic condensation followed by dose dependent cell death. Our results demonstrate FMSP-nanoparticles have ability to induce cell death in MCF-7 cells and may be considered as a potential anti-cancer agent for breast cancer treatments.
Daily Intake Estimation for Young Children’s Ingestion of Residential Dust and Soils Contaminated with Chlorpyrifos and Cypermethrin in Taiwan
Authors: Yang Ya-Qing , Yiin Lih-Ming
Published: May 2018

We estimated the daily intakes of chlorpyrifos and cypermethrin via ingestion of indoor dust and outdoor soils using the Stochastic Human Exposure and Dose Simulation Model on a probabilistic approach for Taiwan’s homes. Variable information for the daily intake estimation, such as concentration, ingestion rate, body weight, was adopted from previous studies. Monte Carlo simulation was performed with 1,000,000 iterations to simulate a single daily intake, which was shown in terms of percentage of the Acceptable Daily Intake (ADI) of either insecticide. The daily intakes were minimal with a 99% probability; at 99.9th percentile, however, the total intakes leaped to 13.1% and 20.0% of the respective ADIs of chlorpyrifos and cypermethrin. The sensitivity analysis indicated that concentration was the most determinant variable. Compared to the data of daily intakes via dietary ingestion of vegetables derived from a previous study, the estimated intakes by this study were considerable at the highest percentile, which referred to insecticide residues few days after insecticide application. Consequently, the non-dietary ingestion exposure to either insecticide was negligible in most cases; nevertheless, for those with indoor insecticide applications, the daily intakes for young children could be of concern. Frequently home cleaning is recommended to reduce the exposure.
Ni(NH3)2(NO3)2 – A 3-D Network Through Bridging Nitrate Units Isolated from the Thermal Decomposition of Nickel Hexammine Dinitrate
Authors: Breternitz Joachim , Godula-Jopek Agata , Gregory Duncan H.
Published: May 2018

Nickel nitrate diammine, Ni(NH3)2(NO3)2, can be synthesised from the thermal decomposition of the nickel nitrate hexammine, Ni[(NH3)6](NO3)2. The hexammine decomposes in 2 distinct steps; the first releases 4 equivalents of ammonia while the second involves the release of NOx, N2 and H2O to yield NiO. The intermediate diammine compound can be isolated following the first deammoniation step or synthesised as a single phase from the hexammine under vacuum. Powder X-ray diffraction (PXD) experiments have allowed the structure of Ni(NH3)2(NO3)2 to be solved for the first time. The compound crystallises in orthorhombic space group Pca21 (a = 11.0628 (5) Å, b = 6.0454 (3) Å, c = 9.3526 (4) Å; Z = 4) and contains 11 non-hydrogen atoms in the asymmetric unit. Fourier Transform Infrared (FTIR) spectroscopy demonstrates that the bonding in the ammine is consistent with the structure determined by PXD.
Characterization of Small Molecules Inhibiting Pro-Angiogenic Activity of the Zinc Finger Transcription Factor Vezf1
Authors: He Ming , Yang Qianyi , Norvil Allison , Sherris David , Gowher Humaira
Published: May 2018

Discovery of inhibitors for endothelial-related transcription factors can contribute to the development of angiogenic therapies that treat diseases ranging from cardiovascular to cancer. The role of transcription factor Vezf1 in vascular development and regulation of angiogenesis has been defined by several earlier studies. Through construction of a computational model for Vezf1, work here has identified a novel small molecule drug capable of inhibiting Vezf1 from binding to its cognate DNA binding site. Using structure-based design and virtual screening of the NCI Diversity Compound Library, 12 shortlisted compounds were tested for their ability to interfere with the binding of Vezf1 to DNA using electrophoretic gel mobility shift assays. We identified one compound, T4, which has an IC50 of 20uM. Using murine endothelial cells, MSS31, we tested the effect of T4 on endothelial cell viability and angiogenesis by using tube formation assay. Our data show that addition of T4 in cell culture medium does not affect cell viability at concentrations lower or equal to its IC 50 but strongly inhibits the network formation by MSS31 in the tube formation assays. Given its potential efficacy, this inhibitor has significant therapeutic potential in several human diseases raging from wound healing to cancer.
Visualization of Annular Gap Junction Vesicle Processing: The Interplay between Annular Gap Junctions and Mitochondria
Authors: Bell Cheryl L. , Shakespeare Teresa I. , Murray Sandra A.
Published: May 2018

It is becoming clear that in addition to gap junctions, playing a role in cell-cell communication, gap junction proteins, connexins, located in cytoplasmic-compartments may have other important functions. Mitochondrial connexin 43 (Cx43) is increased after ischemic preconditioning and has been suggested to play a protective role in the heart. How Cx43 traffics to the mitochondria and the interactions of mitochondria with other Cx43-containing structures are unknown. In this study, immunocytochemical, super-resolution and transmission electron microscopy were used to detect cytoplasmic Cx43-containing structure and to demonstrate their interactions with other cytoplasmic organelles. The most prominent cytoplasmic Cx43-containing structures, annular gap junctions, were demonstrated to form intimate associations with lysosomes as well as with mitochondria. Surprisingly, the frequency of associations between mitochondria and annular gap junctions was greater than that between lysosomes and annular gap junctions. The benefits of annular gap junction/mitochondrial associations are not known. However, it is tempting to suggest that the contact between annular gap junction vesicles and mitochondria facilitates Cx43 deliver to the mitochondria. Furthermore, it points to the need for investigating trafficking of Cx43 to cytoplasmic compartments and annular gap junction as more than only a vesicle destined for degradation.
Kinetics of Highly Active TiO2 Microspheres Formation in a Presence of Ethylammonium Nitrate Ionic Liquid
Authors: Gołąbiewska Anna , Checa-Suárez Micaela , Paszkiewicz-Gawron Marta , Lisowski Wojciech , Raczuk Edyta , Klimczuk Tomasz , Polkowska Żaneta , Grabowska Ewelina , Zaleska-Medynska Adriana , Łuczak Justyna
Published: May 2018

Spherical microparticles of TiO2 were synthesized by the ionic liquid-assisted solvothermal method at different reaction time (3, 6, 12 and 24h). The properties of the prepared photocatalysts were investigated by means of UV-vis diffuse-reflectance spectroscopy (DRS), BET surface area measurements, scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), and X-ray photoelectron spectroscopy (XPS). The results indicated that the efficiency of phenol degradation was related with a time of the solvothermal synthesis as determined for TiO2_EAN(1:1)_24h sample. Microparticles of TiO2_EAN(1:1)_3h formed during the only 3h of synthesis time revealed really high photoactivity under visible irradiation – 75%. This value increased to 80% and 82% after 12h and 24h, respectively. The photoactivity increase was accompanied by the increase of the specific surface area thus pores size, as well as ability to absorb UV-vis irradiation. The high efficiency of phenol degradation of IL-TiO2 photocatalysts was ascribed to the interaction between the surface of TiO2 and ionic liquid components (carbon and nitrogen).
Photovoltaic Energy in Colombia: Current Status of Supply Chain
Authors: Valderrama Mendoza Mateo , Ocampo Vélez Pablo César , Mejía Moncayo Camilo , Rodríguez Urrego Leonardo
Published: May 2018

This article makes a general analysis of the supply chain of photovoltaic systems in Colombia, taking as a starting point a conceptual base and the current situation of the country in this sector. This article especially will contemplate the non-interconnected areas (ZNI) to the electricity grid in the national, due to its complexity in the logistics issues. Likewise, the work performs a graphical representation of the stages and processes of the supply chain using a powerful-modeled tool such as the Petri Nets (PNs). Finally, it identifies some of the flaws in the operation and the joint of all the links of the logistic part and from there it is based the importance of the strategy of orientation to the supply chain (SCO) as a possible alternative to improve and to enhance the logistic processes of this type of systems.
Vertically Resolved Precipitation Intensity Retrieved Through a Synergy Between the Ground-Based NASA MPLNET Lidar Network Measurements, Surface Disdrometer Datasets and an Analytical Model Solution
Authors: Lolli Simone , D'Adderio Leo Pio , Campbell James R. , Sicard Michael , Welton Ellsworth J. , Binci Andrea , Rea Alessandro , Tokay Ali , Comerón Adolfo , Barragan Ruben , Baldasano Jose Maria , Gonzales Sergi , Bech Joan , Afflitto Nicola , Lewis Jasper R.
Published: May 2018

In this paper we illustrate a new, simple and complementary ground-based methodology to retrieve the vertically resolved atmospheric precipitation intensity through a synergy between measurements from the National Aeronautics and Space Administration (NASA) Micropulse Lidar network (MPLNET), an analytical model solution and ground-based disdrometer measurements. The presented results are obtained at two mid-latitude MPLNET permanent observational sites, located respectively at NASA Goddard Space Flight Center, USA, and at the Universitat Politècnica de Catalunya, Barcelona, Spain. The methodology is suitable to be applied to existing and/or future lidar/ceilometer networks with the main objective of either providing near-real time (3h latency) rainfall intensity measurements and/or to validate satellite missions, especially for critical light precipitation (<3 mm hr−1).
Study on Burnout Risk and Protection Factors in Certified Nursing Aides
Authors: Molero Jurado María del Mar , Pérez-Fuentes María del Carmen , Gázquez Linares José Jesús , Simón Márquez María del Mar , Martos Martínez África
Published: May 2018

1) Background: Studies have shown that there is a higher risk of burnout among employees in the healthcare sector. Therefore, this study focused on “Certified Nursing Aides” (CNAs) who have shown a high prevalence of burnout, and are therefore considered an especially vulnerable group. The objective of this study was to identify the relationships between some organizational, personal and sociodemographic factors and burnout; 2) Methods: The final study sample was made up of 278 working CNAs with a mean age of 40.88 (SD=9.41). To compile the data, an ad hoc questionnaire was used to collect sociodemographic information, and to collect professional and employment information, the Brief Emotional Intelligence Inventory for Adults, the Brief Questionnaire on Perceived Social Support, and The General Self-Efficacy Scale.; 3) Results: The results show that the Burnout Syndrome is significantly related negatively to all the emotional intelligence factors, self-efficacy and perceived social support. The risk of burnout is higher in younger persons and in permanently employed professionals. General self-efficacy and stress management act as protective factors against the likelihood of burnout.; and 4) Conclusions: This study suggests that organizations should urge coaching and transformational leadership training programs to promote the wellbeing and organizational commitment of workers.
Wheel Force Sensor Based Techniques for Lose Detection and Analysis of the Special Road
Authors: Yan Huawen , Zhang Weigong , Wang Dong
Published: May 2018

Automobile proving ground is important for the research of vehicles which is used for the vehicle dynamics, durability testing, braking testing, etc. However, the roads in automobile proving ground will inevitably be damaged with the extension of the service life. In most previous researches, equipment similar to laser cross-section was used to detect pavement quality, the principle of which was to reflect pavement quality by detecting road surface roughness. This method ignores the elastic deformation of the roads itself when the vehicle is traveling on it and hardly compensate for the amendment. Therefore, this article presents a new method based on force sensor to reduce the impact of elastic deformation such as wheel tyre deformation, pavement deformation, and wheel rim deformation. In which, force sensors mounted on the wheels collect the three-dimensional dynamic load of the wheel.The presented method has been tested with two sets of cobblestone road load data, and the results show that The　incentives imposed by the test vehicle on the target road are 88.3%, 91.0%, and 92.05% of the incentives imposed by the test vehicle on the standard road in three dimensions, respectively. It is clear that the proposed method has strong potential effectiveness to be applied for lose detection of the special road application.
Construction Technology Adoption Cube: An Investigation on Process, Factors, Barriers, Drivers, and Decision Makers using NVivo and AHP Analysis
Authors: Sepasgozar Samad , Davis Steven
Published: May 2018

Due to the complexity, high-risk, and conservative character of construction companies, advanced digital technologies do not become widely adopted in the short term, while vendors make determined efforts to overcome this and disseminate their technologies. This paper presents the methods of an investigation addressing the extremely complex issues related to the current practices of digital technology adoption in construction. It discusses how construction companies follow a specific logical process linked to need, project objectives, characteristics of the adopting organization, and the characteristics of the new technology to be adopted. The study aims to demonstrate a novel method of data collection and analysis including data and methodological triangulation techniques including the use of NVivo and AHP to explore how companies make the decision to uptake a new technology (e.g. advanced crane, tunnel boring machine or drones) by focusing on customer and vendor activities, their interactions, contributing factors, and people involved in the process. The major original contribution of this paper is to develop an innovative methodological Cube for investigating the Construction Technology Adoption Process (CTAP) covering technology adoption, acceptance, diffusion and implementation concepts. CTAP is a framework that delineates the phases of the process that customer organizations use when deciding to adopt a new digital technology and the parallel vendor activities. The significance of these contributions is that they enable vendors to understand how to match their strategies with customer expectations in each phase of the CTAP. It also provides a benchmark for new construction companies to use the current best practice of decision making. Future research is warranted to more clearly delineate any differences with developing nations or related industries such as mining and property management.
Influence of Single Fracture Inclination on Fault Activation
Authors: Zhu Yujie , Liu Xiaoli , Wang Enzhi , Wang Sijing , Zhong Jianwen
Published: May 2018

Pre-existing fracture and secondary cracks in rock mass are formed by natural power, such as magma condensed to igneous rocks and tectonic movement. The orientation and inclination of these fractures obey certain laws relating to the stress, temperature, minerals, water and so on. Therefore, cracks react differently under the same external loading on the condition of various inclination, fissure apertures, stiffness and joint roughness. To simulate the crack propagation, experiments on hollow cylinder cut by one oblique interface mimicking single fracture accumulated numerous data discovering the failure criterion in accordance with the Mohr-Coulomb criterion. And theory on the Terzaghi’s effective principle take an essential role in controlling the behavior of triggering fault. This paper introduced a series of oblique plane cutting the cylinder regarded as fractures at different inclination to concentrate on how the fracture characteristics effect the stress and strain distribution inside the specimen, especially, the relationship between displacement and water head. The key point of this numerical simulation is coupling the solid phase and the fluid phase, specifically, the mechanic and seepage field. According to the statics, curves referring to deformation and water head could be described as increasing lines. Besides, simulation on coupling solid phase and fluid phase can supply crucial evaluation on activating existing fault, and thus predicting induced seismicity in reservoirs or estimating damage in shale gas exploration.
Computational Fluid Dynamics (CFD) Investigation of
Wind Turbine Nacelle Separation Accident over Complex Terrain in Japan
Authors: Takanori Uchida
Published: May 2018

We have developed an unsteady and non-linear wind synopsis simulator called RIAM-COMPACT (Research Institute for Applied Mechanics, Kyushu University, COMputational Prediction of Airflow over Complex Terrain) in order to simulate the airflow on a microscale, i.e., a few tens of km or less. In RIAM-COMPACT, the large-eddy simulation (LES) has been adopted for turbulence modeling. LES is a technique in which the structures of relatively large eddies are directly simulated and smaller eddies are modeled using a sub-grid scale model. In the present study, we have conducted the numerical wind diagnoses for Taikoyama Wind Farm nacelle separation accident in Japan. The simulation results suggest that all six wind turbines at the Taikoyama Wind Farm are subject to significant influence from separated flow (terrain-induced turbulence) which is generated due to the topographic irregularities in the vicinity of the wind turbines. A proposal has been also made on reconstruction of the wind farm.
Rett Syndrome: Treatment with IGF-1, Melatonin, Blackcurrant Extracts, and Rehabilitation
Authors: Devesa Jesús , Devesa Olga , Carrillo María , Casteleiro Nerea , Devesa Ana , Llorente David , González Cristina
Published: May 2018

1) This study describes the good evolution of a 6-year-old girl genetically diagnosed with Rett syndrome (RTT), after having been treated with IGF-1, MT (MT), blackcurrant extracts (BC), and rehabilitation during 6 months. 2) The patient stopped her normal development from the first year of age. The patient showed low weight and height and met the main criteria for typical RTT. Curiously, there was pubic hair (Tanner II), very high plasma testosterone, despite low gonadotropins. No adrenal enzymatic deficits existed, and ultrasound abdominal studies were normal. Treatment consisted in IGF-1 (0.04 mg/kg/day, 5/week, sc) during 3-months and then 15-days resting, MT (50 mg/day, orally, uninterruptedly) and neurorehabilitation. The new blood tests were absolutely normal and the pubic hair disappeared. Then, a new treatment with IGF-1, MT, and BC started for another 3 months. After it, pubic Tanner stage increased to III, without a known cause. 3) The treatment followed led to clear improvements in most of the initial impairments, perhaps because of the effect of IGF-I, the antioxidant effects of MT and BC, and the increase in cyclic-glycine-proline (cGP) after BC administration. 4) A continuous treatment with IGF-1, MT and BC may recover most of the neurologic disabilities that occur in RTT.
Dietary Cholesterol Intake and Sources among U.S Adults: Results from National Health and Nutrition Examination Surveys (NHANES), 2001–2014
Authors: Xu Zhe , McClure Scott T. , Appel Lawrence J.
Published: May 2018

The 2015 Dietary Guidelines for Americans recommends that individuals should eat as little dietary cholesterol as possible. However, current dietary cholesterol intake and its food sources have not been well-characterized. We examined dietary cholesterol intake by age, sex, race, and food sources using 24-hour dietary recall data from a nationally representative sample of 5047 adults aged 20 years or older who participated in NHANES (2013–2014 survey cycle). We also reported trends in cholesterol intake across the past 7 NHANES surveys. Mean dietary cholesterol intake was 293 mg/day (348 mg/day for males and 242 mg/day for females) in the 2013–2014 survey cycle; 39% of adults had dietary cholesterol intake above 300 mg/day (46% for males and 28% for females). Meat, eggs, grain products, and milk were the highest four food sources of cholesterol, contributing to 96% of the total consumption. Both average cholesterol intake and food source varied by age, sex, and race (each p < 0.05). Mean cholesterol intake of the overall population had been relatively constant at ~290 mg/day from 2001–2002 to 2013–2014 (p-trend = 0.98). These results should inform public health efforts in implementing dietary guidelines and tailoring dietary recommendations.
Performance Evaluation and Lubrication Mechanism of Water-Based Nanolubricants Containing Nano-TiO2 in Hot Steel Rolling
Authors: Wu Hui , Zhao Jingwei , Luo Liang , Huang Shuiquan , Wang Lianzhou , Zhang Suoquan , Jiao Sihai , Huang Han , Jiang Zhengyi
Published: May 2018

Hot rolling tests of a low-alloy steel were conducted at a rolling temperature of 850 ℃ under different lubrication conditions, including benchmarks (dry condition and water) and water-based nanolubricants containing different concentrations of nano-TiO2 from 1.0 to 8.0 wt%. The effects of nanolubricants on rolling force, surface roughness, thickness of oxide scale and microstructure were systematically investigated through varying nano-TiO2 concentrations. The results show that the application of nanolubricants can decrease the rolling force, surface roughness and oxide scale thickness of rolled steels, and refine ferrite grains. In particular, the nanolubricant containing an optimal concentration (4.0 wt%) of nano-TiO2 demonstrates the best lubrication performance, owing to the synergistic effect of lubricating film, rolling, polishing and mending generated by nano-TiO2.
Pola dan Dampak Mobilitas Petani menjadi Tukang Becak di Kecamatan Purworejo
Authors: Padmaningrum Dwiningtyas , Widiyanti Emi
Published: May 2018

The population mobility happened if there are difference value between urban and rural specially at the economic and opportunity of job aspect. The pattern of population mobility: permanent and non-permanent (circulair and commuting). Mobility pattern of responder in this research entirely represent non permanent mobility, consisting of mobility commute (63,3 percent) and also circulair mobility (36,7 percent). As for decision to do mobility because invited by their friend or family and also coincidence of this work is can access. This mobility affect positive to responder, social and also economics.
PARTISIPASI MASYARAKAT DALAM PENGELOLAAN HUTAN MANGROVE DI DESA SEGARAJAYA, KECAMATAN TARUMAJAYA KABUPATEN BEKASI
Authors: Yuliani Shahibah , Herminasari Nova Scorviana
Published: May 2018

The purpose of this research is to know the community participation management of mangrove forests in PAL Jaya Beach, Segarajaya Village Tarumajaya District, Bekasi. This study uses descriptive method, which aims to find information from  by using the questionnaire (closed questionnaire), direct observation, interviews, and documentation. The subjects of this study were 25 people consisting of members of the Supervisory Society Group (POKMASWAS), Ikatan Pemuda Putera Daerah (IKAPUD), and other communitie. The results showed that community participation management of mangrove forests is relatively high from the aspects of planning and activities implementation (restoration). Community participation is also supported by several institutions cooperate such as socialization, mangrove planting, and development of mangrove forest area. However, community involvement in treating mangroves have been low. Related to community participation in utilizing mangrove forests is still educatiobal tourist area
IDENTIFIKASI KEBUTUHAN PUSAT SUMBER BELAJAR PADA SEKOLAH LANJUTAN PERTAMA DAN SEKOLAH LANJUTAN ATAS DI INDONESIA
Authors: Situmorang Robinson
Published: May 2018

This research covering 30 junior High School in 10 regions in Indonesia aims at identifying the needs for learning resource center. the findings show that all schools have performed the funcion of learning resource center in instructional activities and 70% of the teachers has used media in their instructions; 78% of the schools have included learning resource center in their school stuctures; but only 30% of them treat the learning resource centers as formal organizations. more over, 90% of the schools provide special room for learning resource center which are generally used for Audio Visual. besides, the hardware and software of learning resources are not as complete as they should be. Based on the findings this research recomends the goverment facilitates the schools to develop learning resources center in each school as it has important and strategic roles in improving the quality of instructional process and competencies.
KEBIJAKAN PEMERINTAH DAERAH DALAM ANGGARAN SEKTOR PENDIDIKAN
Authors: JahJa Yudrik
Published: May 2018

Based on the 1945 Constitution, the government is obliged to provide annual budget for conducting national education at amount of 20% from APBN and APBD. The implementation of this regulation is controversial and has not been done fully. This article discusses the provision of education budget by reviewing the rule of region in contributing there local budget for education development in their regions. It is concluded that in general the contribution of each region is still low. The article suggests that the local governments should improve their policy in allocating their budget for education development to improve the quality as well as the quantity of education in their own regions.
Affordable Care Act Impact in Kentucky: Increasing Access, Reducing Disparities
Authors: Blewett Lynn A. , Planalp Colin , Alarcon Giovann
Published: May 2018

Objectives. To examine health insurance disparities since Kentucky’s implementation of the Affordable Care Act (ACA).

Methods. Using the American Community Survey, we estimated coverage rates by race/ethnicity before and after implementation of the ACA (2013 and 2015), and we estimated whether groups were over- or underrepresented among the uninsured, compared with their share of the state population.

Results. Kentucky’s uninsurance rate declined from 14.4% in 2013 to 6.1% in 2015 (P < .001). Uninsurance rates also declined for most racial/ethnic groups, including Blacks (16.7% to 5.5%; P < .001) and Whites (13.3% to 5.3%; P < .001). In 2015, Blacks were no longer overrepresented among Kentucky’s uninsured, with a significant decline in the ratio of Blacks among the state uninsured population compared with their share of the state population (1.16–0.91; P = .045).

Conclusions. In Kentucky, which mounted a robust implementation of the ACA—including Medicaid expansion, a state-based marketplace, and an extensive outreach and enrollment campaign—the state experienced not only a decline in the overall uninsurance rate but also an elimination in coverage disparities among Blacks, who historically were overrepresented among the uninsured.
Análise de custo-efetividade da rivaroxabana versus enoxaparina no tratamento da trombose venosa profunda em pacientes com câncer ginecológico
Authors: Leira Rafael Roberto , Costa Rodrigo
Published: May 2018

Objetivo: A trombose venosa profunda (TVP) é uma das principais complicações em pacientes com câncer e tem impacto socioeconômico relevante. Novos anticoagulantes orais inibidores diretos do fator X estão sendo introduzidos na prática clínica, prometendo trazer maior facilidade no seu manejo. Porém, os protocolos clínicos ainda não discutem o emprego deles em pacientes com câncer, principalmente pela falta de evidências. Este artigo avalia o custo-efetividade da rivaroxabana (RVXB) versus enoxaparina (ENOXA) no tratamento da TVP em pacientes com câncer ginecológico. Métodos: Foi realizada uma análise de custo-efetividade sob a perspectiva de um hospital federal do SUS. A partir de um modelo de árvore de decisão, foram considerados os desfechos de efetividade e segurança da RVXB e da ENOXA em tratamento ambulatorial, sendo os dados clínicos extraídos de uma coorte retrospectiva e os custos diretos obtidos das plataformas SIGTAP-SUS e do Ministério da Saúde. Resultados: Sessenta e cinco pacientes foram selecionados e tiveram tempo médio de sete meses de tratamento. O custo de tratamento com a RVXB e a ENOXA foi de R$ 1.172,02 e R$ 7.490,49, respectivamente, com custo incremental de R$ 7.789,61 por paciente tratado com ENOXA. A robustez do modelo foi testada por análises de sensibilidade determinísticas e a economia de recursos promovida pela rivaroxabana foi mantida em todas as variações. Conclusão: A RVXB neste contexto é a tecnologia dominante no tratamento ambulatorial de pacientes com câncer ginecológico como importante alternativa farmacoterapêutica.
Análise de custo por evento evitado (COPE) da associação de cobimetinibe e vemurafenibe e outras opções terapêuticas para o tratamento de melanoma metastático com mutação BRAF V600
Authors: Souza Paulo Vitor , Bellan Jamilson Eduardo , Alves Marcia Regina
Published: May 2018

Objetivo: O melanoma maligno é o tipo de neoplasia de pele com pior prognóstico devido ao seu elevado potencial de gerar metástases e a sua letalidade. Algumas diretrizes internacionais recomendam a combinação de inibidores da via das proteínas quinases BRAF e MEK para o tratamento de melanoma metastático ou irressecável com mutação positiva BRAF V600 em primeira linha. Um estudo demonstrou que, em termos de sobrevida livre de progressão (SLP), a associação de cobimetinibe + vemurafenibe foi a opção terapêutica que proporcionou menor valor de número necessário para tratar (NNT) para o tratamento de melanoma metastático com mutação BRAF V600 em primeira linha. O objetivo desta análise foi de avaliar o custo por evento evitado (COPE) de cobimetinibe em associação com vemurafenibe no tratamento do melanoma irressecável ou metastático, positivos para mutações BRAF V600. Métodos: A análise econômica adotou a perspectiva do Sistema de Saúde Suplementar brasileiro. Os comparadores avaliados foram vemurafenibe monoterapia, dabrafenibe + trametinibe, nivolumabe e ipilimumabe. O COPE foi obtido pelo produto do NNT, baseado na SLP em 12 meses, reportado por Ho et al. e do custo de tratamento considerando custos de aquisição dos medicamentos e manejo de eventos adversos. Resultados: A maior eficiência da associação de cobimetinibe e vemurafenibe foi capaz de proporcionar o menor COPE (R$ 1.204.229) entre todos os comparadores da análise, demonstrando que, com um menor número de pacientes tratados, se observa um caso de sucesso com a terapia combinada, mesmo que esta apresente um custo anual de tratamento superior (R$ 626.477). Conclusão: A associação de cobimetinibe e vemurafenibe foi a mais eficiente em termos de NNT e COPE no melanoma metastático não tratado previamente.
Índice de hospitalização e custos associados à doença pulmonar obstrutiva crônica (DPOC) entre estados que padronizaram versus que não padronizaram o tiotrópio – dados do mundo real
Authors: Melo Thais , Santoni Natália , Finkelstein Beny José , Veiga Daniela , Nascimento Marcos Henrique , Rosito Fabio César
Published: May 2018

Objetivo: Avaliar, por meio de dados do mundo real (DATASUS) e análises estatísticas, o impacto da inclusão do tiotrópio no tratamento da doença pulmonar obstrutiva crônica (DPOC), comparando o índice de hospitalização e custos associados à internação nos estados que possuem o tiotrópio padronizado em suas diretrizes de tratamento comparados aos estados que não o incluem. Método: Estudo retrospectivo histórico realizado entre 2013 e 2015, a partir de dados obtidos do DATASUS, portais de compras públicas estaduais e Secretarias de Saúde Estaduais. Todos os índices foram normalizados pelo número da população, de acordo com os dados atualizados do IBGE. Foi utilizado o teste Z para avaliar a significância estatística dos resultados. Resultados: A análise combinada do grupo com tiotrópio apresentou 52,4% menos hospitalizações em comparação ao grupo sem tiotrópio (90,0/100.000 versus 43,3/100.000, respectivamente, p < 0,01). O gasto total para o sistema único de saúde com hospitalização por DPOC foi de R$ 2,3 milhões e R$ 4,8 milhões para o grupo com tiotrópio vs. grupo sem tiotrópio, respectivamente (p = 0,0003). Houve diferença significativa entre os grupos quanto ao número total e gastos totais de internação por DPOC, nos estados nos quais o tiotrópio estava padronizado e nos estados sem o tiotrópio padronizado. Conclusão: A análise dos resultados sugere redução significativa no número de internações por DPOC e seus respectivos gastos nos estados nos quais o tiotrópio está padronizado.
Introduction
Authors: Jo Ji-Yeon O.
Published: May 2018

In this chapter I provide an overview of the book and introduce its conceptual and theoretical articulations. Using the frameworks of affect and global modernity, I delineate the trajectories of mobility involved in later-generation diaspora Koreans’ migration to contemporary South Korea. This serves as a springboard for laying out theories of borders and belonging that help make sense of legacy migrants’ trajectories and experiences. In outlining the book’s chapters, I explain how each adds a new dimension of understanding to transborder belonging. I also suggest that four borders—social spaces, citizenship and nationality law, Korean as a heritage language, and family—intersect to make and remake the notion of Korean peoplehood.
Contouring Social Spaces
Authors: Jo Ji-Yeon O.
Published: May 2018

I take up fundamental questions regarding later-generation diaspora Koreans and their migration to South Korea. Who are the later-generation diasporas who embark on migratory journeys to South Korea? Why do they migrate to South Korea? What has influenced their sense of South Korean society and of belonging to “imagined homeland”? I explore the divergent homing trajectories taken by Korean Chinese, CIS Koreans, and Korean Americans, as well as the diverse professions, roles, and responsibilities that they perform in South Korea. I further explore the social spaces that legacy migrants have established in South Korea, looking at how they went about creating those spaces and the nature of their engagement with Koreans and Korean society—specifically, how they determined what sort of social spaces they needed and how the social spaces they produced reflected their affective reality in South Korean society.
Enterprising State and Entrepreneurial Self
Authors: Jo Ji-Yeon O.
Published: May 2018

I trace how conceptions of citizenship have transformed in post-1990 South Korea, focusing on the major formations of and shifts in Korean citizenship, as well as on the evolution of nationality laws concerning diaspora Koreans. I also examine legacy migrants’ perspectives on citizenship and legal belonging. The process of citizen-making, which unfolds through the dynamics between an “enterprising” South Korean state and the “entrepreneurial” strategies incorporated by the legacy migrants in this study, largely rests on the interplay between emotionally charged ethnic nationalism and economic mobility driven by neoliberal global capitalism, both of which in turn have rearticulated and reconfigured the borders of South Korean citizenship and belonging. As a result, various forms of conditional and contingent citizenship—statuses that are neither fully admitted by the state nor fully committed to by returnees—have been produced.
Negotiating Transborder Kinship
Authors: Jo Ji-Yeon O.
Published: May 2018

I investigate how the interplay between legal-juridical notions of citizenship and socioculturally mediated belonging affects the family lives of return migrants, as well as how and why transborder ties between returnees and their kin have been maintained or broken. I pay special attention to the production of transborder kinship by paying heed to the lives of families across and within nation-state borders. Here, family composition and living arrangements, especially those involving parents and children, often defy normative understandings of family. I investigate how such arrangements have been necessitated by the transnational movements of my interlocutors and their affective connections with each other and with the Korean nation. And though returnees maneuver their locations in time and space in order to accommodate their family lives, their family lives have nevertheless been interrupted by their migration to South Korea, which has repercussions for their affective topographies.