bluuebunny/crossref_metadata_2025 huggingface dataset:
Bell Ringing in Latin Pera: Sounds and Silence
Authors: Rodriguez Suarez Alex
Published: January 2023

The cultural and architectural history of Pera, also known as Galata, has been the focus of many studies.
However, its soundscape has not attracted much scholarly interest to date. The present study fills part
of this gap by tracing the history of bell ringing in the settlement. Written and material evidence sheds
light on the use of bells by the Latin community of Pera from the period of Genoese rule until the late
Ottoman Empire. Sounds and silence provide new insights into the long history of the Latin presence in
Pera and its evolution throughout the centuries.
‘Hands at Work’: Patching Women’s Film Histories through Sabrina Gschwandtner’s Film Quilts
Authors: Ljungbäck Hugo
Published: January 2023

This paper examines the work of artist Sabrina Gschwandtner, whose recent series of 16mm and 35mm film quilts reproduce sequences from early women directors’ films and from orphaned textile-production documentaries and re-edits their narratives through spatial montage by sewing celluloid strips into traditional quilt patterns. Appropriated from film archives, each strip of film holds embedded within it a history of women’s labor, and through her sewing techniques, which call attention to the connection between film’s intermittent motion mechanism and the sewing machine, Gschwandtner patches women’s film histories back together. By considering the techniques of colorists and editors in early cinema as originating within handcrafting and ‘feminine’ labor, the traces of their hands at work form new histories through Gschwandtner’s quilts. In her artwork, the invisible contributions of these forgotten women become visible, foregrounding their tactile, intensive, and time-consuming labor. Gschwandtner’s film quilts also suggest that, rather than digital technology marking the death of cinema, it has just liberated the celluloid strip to be used and encountered in endless new ways.
Audiovisual Means to Therapeutic Ends. The Cinematic Dispositive within Medical Humanities
Authors: Sabatino Anna Chiara
Published: January 2023

Dominant narratives across Medical Humanities have been focused on the cultural construction of the notion of medicine as epistemic discourse and social practice, on the role of humanities in medical design of the disease as well as on the humanization of the clinical encounter in order to facilitate the anamnesis, the therapy and the care. Among the main declinations, a more complex point of view arises, suggesting the critical integration and exploitation of a variety of methodologies, previously used by art and humanities research, into a peculiar human-centered dispositive, both narrative and therapeutic, in which audiovisual practices and languages acquire new healing potential and activate bias for unprecedented processes of subjectivization for particular target of suffering human beings.
Based on the aforementioned premises, the essay aims at investigating the therapeutic set as performative and methodological model, consistent with art-therapy and narrative-based medical approaches, applicable in specific pathological conditions and health-care contexts. Within such reflexive and operational framework including documentary studies and visual anthropology, self-representational and amateur theories, the therapeutic set becomes a media environment where the formative encounter, both technical and pragmatic, finally ethical, between the self and the world, the action and the awareness takes place.
My purpose is to explore the theoretical pillars of the therapeutic set as transformative interplay between profaned cinematic dispositive and psychotherapy setting, dwelling on bodily involvement, audiovisual gestures and amateur self representation to which active participants, storytellers of their own illness and treatment, are called in the making of therapy and narrative.
The paper finally intends to illustrate selected interdisciplinary case studies in order to discuss the healing potential of creative participatory processes and self-representations, occurring thanks to the relocation and amateurization of the contemporary cinematic experience.
Intra-Active Sense-Making. Towards a Performative Understanding of Biomedical Imaging
Authors: Miglio Nicole , Galimberti Giulio
Published: January 2023

Our paper is situated within the broader exploration of the epistemic and aesthetic potential of biomedical imaging technologies on the human lived experience. Intra-Active Sense-Making is guided by the grounding thesis that imaging technology ought to be understood as a set of material, rhetorical and performative processes, and as a way to challenge the ocularcentric presuppositions. By drawing on the new materialistic theses that phenomena are not pre-existent to intra-action, and that agency should be understood as distributed on human, animal, objectual, and ‘physical’ levels, we offer a performative understanding of biomedical imaging operations complementary to the reflective paradigm. Biomedical imaging may be understood through our idea of intra-active sense-making; while much literature states that medical imaging establishes a view of the self as quantified, atomized, and governable, we argue that the co-configuration of human senses and digital sensors is a source of new sense-making capabilities.
On the Frontier Between Medicine and State: Traumatic States of Embodiment and Temporality in Waad Al-Kateab’s For Sama and Wang Nanfu’s In the Same Breath
Authors: Sedzielarz Aleksander
Published: January 2023

Set in the zone of egregious war crimes against the civilian population of Aleppo and in the biohazard zones of the encroaching COVID-19 epidemic, Waad Al-Kateab’s For Sama and Wang Nanfu’s In the Same Breath invent documentary approaches that create complex temporalities — modes of cinematic address that engage trauma as a field of experience that has been absorbed within institutional discourses of state power built through crises. Filmed in zones of crises in which hospitals exist in states of exception that generate and guarantee state sovereignty, the traumatic scene of crisis becomes both excess and fragment that documentary form contains and interprets. This analysis draws on Ruth Leys’ ‘genealogy’ of trauma and Lisa Guenther’s notion of the ‘necrobiopolitical rituals’ of state bureaucracy to show that both documentaries illuminate a fundamental split between discourses of medical knowledge and state power within which cinema asserts fluid and shifting temporalities as a mode of engaging events of crisis as history.
Ocena procesów zarządzania bhp w polskich przedsiębiorstwach
Authors:   Centralny Instytut Ochrony Pracy – Państwowy Instytut Badawczy, Pęciłło Małgorzata , Galwas-Grzeszkiewicz Magdalena
Published: January 2023

Opublikowanie nowej normy ISO 45001 dotyczącej systemów zarządzania bezpieczeństwem i higieną pracy zwróciło uwagę przedsiębiorstw na wdrożone u nich procesy zarządzania bhp i na problem oceny ich funkcjonowania. W artykule przedstawiono wyniki oceny dziewięciu wybranych procesów zarządzania bhp, którą przeprowadzono w 35 przedsiębiorstwach deklarujących działania dostosowujące system zarządzania bhp do wymagań cytowanej normy.
Idiopathic Spontaneous Occurrence of Heterotrophic Occurrence During Pregnancy
Authors: Melian Christina , Shah Aadit , Alvi Emaan , Boyce Brendan , Khan Fazel , Penna James
Published: January 2023

Heterotopic ossification (HO) typically presents in the hip, knee, and elbow joints in the setting of trauma or postsurgical intervention. Less commonly, it may occur secondary to neurologic dysfunction or underlying genetic conditions, but idiopathic HO is rare. Most cases of HO are managed nonoperatively with surgical resection remaining a controversy due to high recurrence rates. We describe a case of idiopathic HO of the shoulder that occurred in the absence of trauma, neurologic dysfunction, or underlying genetic disorder that was treated with surgical excision.
Metabolites in fish and humans as a response to different food ingredients : a metabolomics approach
Authors: Brunel Mathilde
Published: January 2023

The main objective of this thesis was to evaluate metabolomics changes in humans and fish as a response to food/feed consumption. To alleviate the environmental impact of animal production and maximize the use of resources, the valorization of meat by-products might be an attractive alternative. A meat product containing heart and aorta tissue from pork was designed and analyzed for fatty acid and metabolite composition. In comparison with a control of similar qualities, the designed meat product (or test product) showed higher monounsaturated fatty acid and tyramine levels and lower levels of sugars. The test meat product was used in a randomized controlled clinical trial to test for potential health effects in patients showing atherosclerosis symptoms. Patients receiving the test product showed a decrease in blood levels of low-density lipoproteins, total cholesterol, atherogenic index and triacylglycerols. To reduce the impact of animal production on ecosystems, the replacement of feed ingredients by a microbial alternative was realized. In this study, vegetable oils included in the feed of Arctic char (Salvelinus alpinus) were replaced by biomass of the oleaginous yeast (Rhodotorula toruloides). The analysis of the yeast biomass showed safe levels of pollutants and heavy metals. Fish growth and muscle fatty acid profile were similar to the control. A higher liver weight and hepatosomatic index were observed in fish fed including the yeast biomass, albeit no significant difference in liver fat content or in hepatic enzyme activity was observed. Quantification of plasma metabolites revealed higher levels of metabolites involved in energy pathways such as one-carbon metabolism and gluconeogenesis. In conclusion, this thesis showed that metabolomics can be applied to evaluate effects of food/feed at the molecular level in complex systems. It adds knowledge on the effects of meat by-product consumption in the particular case of atherosclerosis symptoms. The fish feed trial showed the possibility of feed modification with a specific yeast.
Halkı Yanıltıcı Bilgiyi Alenen Yayma Suçu (TCK m. 217/A)
Authors: BALCI Murat , ÇAKIR Kerim
Published: January 2023

Dezenformasyonla mücadele kapsamında idari tedbirlerin yeterli ve caydırıcı olmaması son çare olarak ceza kanununa müracaat edilmesini gerekli kılmıştır. Bu kapsamda 13.10.2022 tarih ve 7418 sayılı Kanun’un 29 uncu maddesi ile 5237 sayılı Türk Ceza Kanunu’nun “Özel Hükümler” başlıklı ikinci kitabının “Topluma Karşı Suçlar”ı düzenleyen üçüncü kısmının “Kamu Barışına Karşı Suçlar” başlıklı beşinci bölümünün 217/A maddesinde “Halkı yanıltıcı bilgiyi alenen yayma” başlığıyla müstakil bir suça yer verilmiştir. İhdas edilen suçla sırf halk arasında endişe, korku veya panik yaratmak maksadıyla, ülkenin iç ve dış güvenliği, kamu düzeni ve genel sağlığı ile ilgili gerçeğe aykırı bir bilgiyi, kamu barışını bozmaya elverişli şekilde alenen yayma yaptırım altına alınmıştır.

Çalışmada, halkı yanıltıcı bilgiyi alenen yayma suçunun objektif ve sübjektif unsurları değerlendirilerek, suç tipinin ifade hürriyeti ile kişilerin haber alma/verme hakkına getirdiği sınırlamalar mukayeseli hukuktaki düzenlemeler de dikkate alınarak izah edilecektir. Ayrıca düzenlemenin, suçta ve cezada kanunilik ilkesinin bir sonucu olarak karşımıza çıkan belirlilik ilkesini ihlal edip etmediği tartışmalarına da çalışmada yer verilecektir.
A EFICIÊNCIA HEDGE NO MERCADO DE COMMODITIES: UMA ANÁLISE PARA UMA EMPRESA DO SETOR DO AGRONEGÓCIO
Authors: Tomáz Carlos André da Silva , Monteiro Vitor Borges
Published: January 2023

A utilização de hedge em mercado de derivativos tem se tornado cada vem mais importante, devido à alta volatilidade em commodities agrícolas. Só no ano de 2020, devido a pandemia da covid-19, commodities como milho, soja e trigo, tiveram aumentos consideráveis nos níveis de preços, o que fez com o que as empresas passassem a utilizar o mercado futuro como método para reduzir o risco de oscilações de preços. Este trabalho apresenta uma análise de uma empresa do setor do Agronegócio utilizando os preços do mercado a vista (preço pago pela empresa para a compra das commodities), como também os preços do mercado futuro (preços negociados através de contratos futuros da bolsa de Nova York e Chicago). Através desses preços à vista e futuro, foi feito uma análise tendo em vista verificar se o mercado hedge era eficiente através da metodologia de portifólios sintéticos propostas por Leuthoud, Junkus e Cordier (1989). Utilizando as carteiras ausente de hedge, de variância mínima e eficiente, foi possível verificar que a carteira de variância mínima era a mais eficiente, ou seja, utilizando o mercado futuro na mesma proporção que compra no mercado a vista.
PROSEDUR PEMBUKAAN REKENING DEPOSITO PADA BANK BAPAS PUSAT 69
Authors: Firmansyah Salma Arjuan Yumna
Published: January 2023

This study aims to determine the technique of opening and disbursing closing deposit accounts at BPR BAPAS 69 Magelang Head Office. The method in this study is Descriptive Analysis by defining, illustrating, or summarizing data points so that patterns that meet all data conditions can emerge. The results of this study are that the customer must come to the BAPAS 69 BPR office bringing the requirements (KTP/SIM/PASPOR/KITAS and NPWP), visit the Customer Service counter, submit the required files, and fill out a form for opening a BPR BAPAS 69 deposit account at the Head Office Magelang. As for deposits, filling out deposit slips, deposits at teller counters, and collecting deposits at Customer Service counters are examples of deposit procedures. Complete the KTP/SIM/PASPOR/KITAS and NPWP withdrawal requirements, bring a photocopy of one of the requirements and a stamp along with the deposit slip to the Customer Service counter, fill out the deposit withdrawal form, pay a fine if it is not due, and go to the teller counter to withdraw money at the time BPR BAPAS 69 deposit account disbursement procedure, Magelang Head Office.
ANALISIS VEGETASI AGROEKOSISTEM DAN KERAGAMAN JENIS PISANG (Musa spp.) DI DESA MAJASARI KABUPATEN GARUT
Authors: M. Khais Prayoga dan Ade Ismail
Published: January 2023

Banana is a horticultural commodity that gets priority to be researched and developed because it has the potential to meet domestic or export needs. Majasari Village, Cibiuk District, Garut Regency, West Java Province is one of the centers of banana production with productivity reaching 27 tons/ha. So far there has been no study related to the analysis of agro-ecosystem vegetation and the diversity of banana species in Majasari Village so that the diversity of banana species is unknown and causes there is still much potential banana germplasm that has not been characterized. Therefore, it is necessary to analyze the level of diversity of banana species and their agroecosystem biodiversity in Majasari Village in supporting plant breeding activities. The study was conducted at 21 locations in Majasari Village where the determination of the location was carried out by purposive sampling. The method used in this study is a survey and exploration method as well as interviews with farmers. The results showed that Majasari Village had a high diversity of species in the banana agroecosystem, both annual crops (H = 2.53) and annual plants (H = 2.54). In the banana agroecosystem, 18 types of annual plants were found, 23 types of annual plants were found. The most dominating annual crop is cassava with an INP value of 53,966, while the most dominating annual plant is teak with an INP value of 48,790. From 21 banana agroecosystems in Majasari village, 20 types of bananas were found, consisting of 12 types of fruit bananas and 8 types of processed bananas with a high diversity index (H = 2.67). The dominant type of banana is Ambon banana with an INP value of 37.444%.
Case Report Ramsay Hunt Syndrome presenting as “a window’’ to HIV diagnosis in 48 year old African female: A case report
Authors: Chinyathi A D , Chiweza K B , Kapembwa K C
Published: January 2023

Background: Ramsay Hunt Syndrome in adults is reported in a number of case reports as an uncommon presentation of Varicella zoster Virus infection. Ramsay Hunt Syndrome occurs when there is reactivation of the latent Varicella zoster virus present in the ganglia due to previous varicella infection. Following a breakdown of the immune system, latent Varicella zoster infection can be activated. HIV (Human Immunodeficiency Virus infection), causes immunosuppression and hence reactivation of Varicella zoster. The diagnosis of Ramsay Hunt Syndrome, gives a window of opportunity to investigate for HIV. Here we report our first case of Ramsay Hunt syndrome as a presenting feature of HIV disease in an apparently healthy looking 48 year old black African female who was unaware of her HIV status at the time of presentation.

This case is reported in order to highlight the need to use Ramsay Hunt Syndrome as a window of opportunity to screen for underlying HIV.

 Case presentation: A 48 year old black African female who was unaware of her HIV status, presented to our outpatients department with a two day history of painful right ear pain, vesicles on the right pinna and inability to completely close her right eye, her mouth was deviated to the left, with a wrinkle free frown. She denied any alteration in taste sensation and hyperacusis. She had a grade IV House-Brackmann facial paralysis.A diagnosis of Ramsay Hunt Syndrome was made and an HIV test was offered, the test was positive for HIV.A subsequent HAART (Highly Active Antiretroviral Therapy) work up, revealed   CKD 3B (Chronic Kidney Disease stage 3B) and a CD4 (cluster of differentiation 4) count of 217 cells/µl .She was started on antiretroviral therapy 2 weeks after completing a 10 day regimen of acyclovir. In addition to her drug treatment she received ocular care and physiotherapy. Four months on her facial nerve function has improved modestly.

Conclusion:  An HIV test should be an indispensable part of the Ramsay Hunt syndrome workup, as its diagnosis gives a window of opportunity to diagnose HIV and offer life- saving HAART.
Stress in Humanitarian Workers: Case of the UNHCR Office in Senegal
Authors: Dia S A , Mohamed A S , Fall M Gaye
Published: January 2023

In emerging countries, the consequences of stress remain undervalued. Stress in workplace is increasingly recognized as one of the most serious occupational health hazards reducing workers’ satisfaction and productivity, as well as increasing absenteeism and turnover.1-3 At the beginning, a heavy workload, a lack of recognition of the work done and communication difficulties.4 There is also the need to deal with situations where people feel disarmed (suffering of beneficiaries, war) or, on the contrary, situations of waiting without the possibility of acting for security reasons.5 The aim of our study was to assess the prevalence of stress among the UN Refuges Agency (UNHCR) and its local partner (OFADEC) staff in Dakar, Senegal, and to determine the main stress factors. 

METHODS   

We conducted a descriptive cross-sectional study from May 30 to December 30, 2012. Sixty individuals were selected through random sampling. Using a self-administered questionnaire, we recorded the sociodemographic characteristics, the lifestyle, the working conditions, the career plan and the proposals for improvement, the assessment of the stress and the relational problems. Data was entered and processed by Epi-Info 3.5.4 and Microsoft Excel software.

RESULTS

Fifty-two employees participated in the study: 30 from OFADEC and 22 from UNHCR with a male predominance (sex ratio = 1.73). It was a young population, between 20 and 39 years in 53.84% of the cases (table 1), smoking in 11.53% of the cases and having sleep disorders in 15.38% of the cases. Two-thirds of respondents had a fixed-term contract (78.8%). The prevalence of stress was estimated to be 40.38% (n = 21) predominantly within the male population (sex ratio = 2). Almost all Stressed people (92.9%) worked as a team and 66.7% had been working continuously during the last 12 months. The majority (42.9%, n = 25) felt exhausted, worried (23.8%, n = 12), ill-being (19%, n = 10) and had gone through other several feelings in 14.3% N = 7) of the cases. Two-thirds (71.4%, n = 37) of stressed individuals took an aggressive approach to stress and slightly more than half (56.7%, n = 29) reported being verbally abused.

DISCUSSION

The prevalence of stress was higher compared to certain series reported in the literature.6,7 The type of contract in organizations and NGOs (renewable one-year contract) creates a job insecurity especially at the end of the contract and therefore a source of stress among its employees. The average age of 39 in our series, shows the youthfulness of our study population. The stressed people of our series encountered not only multiple relational problems with refugees, but also with colleagues and hierarchy. Effective management of stress at work requires organizational arrangements that are conducive to the physical and mental health of workers.
Posttraumatic stress among women with HIV in Zambia
Authors: Arnison T , Menon J A , Malambo C , Nilsson D
Published: January 2023

Objective: To examine whether HIV-positive women in Lusaka District, Zambia, displays a higher degree of PTSD-symptoms than a HIV-negative control group.

Method: The study targeted 50 HIV-positive women from four ART-clinics and 42 HIV-negative women from corresponding VCT-units. All sites were located in Lusaka District, Zambia. The HIV-positive women were compared with the control group in regard for PTSD, PTSD-symptoms, dissociative symptoms and history of traumatic experiences. The instruments used were PCL-C, DES-T and LYLES-A. Prior to the main study, the validity of the instruments were assessed with a pilot-sample.

 

Results: Three participants in the HIV-positive group fulfilled the criteria for clinical PTSD (10.7 %), as compared to none in the control group. The HIV-positive group also displayed a significantly higher degree of PTSD-symptoms and previous traumatic experiences, with strong effect sizes, but not for dissociative symptoms. The significant difference in PTSD-symptoms remained while trauma-history was controlled for.

Conclusions: The results of this study clearly indicates that women with HIV are vulnerable to PTSD and that contracting HIV in itself can constitute a psychological trauma in itself. Since PTSD among persons with HIV has been associated with transmission risk behaviours, reduced treatment adherence and a faster disease progression, these findings are important to consider in actions against HIV and AIDS.
Influence of Age and Education on Neuropsychological Tests in Zambia
Authors: Kalungwana Lisa
Published: January 2023

Objective: The purpose of this study is to explore the influence of age, education and reading ability on neuropsychological tests in Zambia.

Methods and Materials: 324 adult participants were recruited from urban and rural areas in Zambia. They had an age range of 19 - 65 and education range of 5 – 19 years of schooling. The Zambia Neurobehavioural Test battery was administered.

Results and Conclusion: Results showed that all test scores had a strong association with education and an inverse relationship with age. Education did not generally offer protection against age-related decline in neuropsychological functioning. Reading level predicted performance on neuropsychological tests better than years of schooling.
APHRODISIAC PROPERTIES OF MUTIMBA VULA AND MWANA APELUKE HERBS SOLD IN LUSAKA, ZAMBIA
Authors: Banda Danny , Nyirenda James , Sijumbila Gibson
Published: January 2023

Background: Male potency has been a talk of many years since humanity existed and the use of various kinds of substances to stimulate sexual desire has been done for many years. Many plant-based concoctions have been released on the Zambian market for consumption without scientifically proven results or effects.

Herbalists, Traditional health practitioners (THPs) have put up many advertisements to spread their market base but all the same without any proven results to show to would-be customers to use a particular product. Two local herbal extracts, Mutimba vula (MTV) and Mwana apeluke (MWN) were studied for the presence of medicinally active components and for their sexual behaviour effects in male rats.

Aim of the study: The main objective of this research work was to determine aphrodisiac properties of MTV and MWN aqueous herbal extracts.

Methodology: Phytochemical screening to determine presence of medicinally active components was performed following standard guidelines. Thereafter, 3 g each of dried powder of MTV and MWN were soaked in 250 mL of distilled water for 3 hours for extraction of active ingredients. Two concentrations, high and low doses of the herbal extracts were administered orally to the treatment groups for 21 days followed by sexual behaviour analysis. Concentration of testosterone in blood samples was determined using a Testosterone Enzyme-Linked Immunosorbent Assay (ELISA) test.

Results: Herbal extracts showed varying amounts of saponins, tannins, flavonoids, alkaloids and glycosides. The mounting frequency (p= 0.039), intromission frequency (p= 0.032) and penile erections increased (p= 0.001) significantly indicating enhanced sexual activity in animals treated with the plant extracts. The results indicated that there was no dose-dependent relationship between serum Testosterone levels and the treatment groups (p= 0.061).

Conclusion: It was established that oral administration of Mutimba vula and Mwana apeluke caused increased sexual performance in rats. However, more studies are needed to exploit the possible mode of action.
A case series report of Tuberculosis patients with Vitamin D deficiency in Zambia
Authors: Lungu P , Lakhi S , Mateyo K , Mubiana E , Mwaba P
Published: January 2023

An association of Vitamin D deficiency with Tuberculosis remains a valid assumption. It has been observed that TB is highly prevalent in certain ethnic groupings and regions of the world.  Populations with darker skins are prone to vitamin D deficiency. The regions inhabited by people with darker skin coincides with high TB burden settings. Vitamin D has a key role in immune-modulation of the host response to Mycobacterium Tuberculosis infection. Studies have demonstrated early sputum culture conversion to negative, clinical recovery and radiological improvement with Vitamin D supplementation. However, there is currently no consensus on the advantages of this supplementation in TB treatment. We present the first case series report of pulmonary TB patients with severe deficiency of Vitamin D in Zambia. Additional data from randomised control studies is warranted.
Multidrug resistance pumps as a keystone of bacterial resistance
Authors: Nazarov Pavel , Kuznetsova Marina , Karakozova Marina
Published: January 2023

Antibiotic resistance is a global problem of modern medicine. A harbinger of the onset of the post-antibiotic era is the complexity and high cost of developing new antibiotics, as well as their ineffi ciency due to the rapidly developing resistance of bacteria. The cornerstone of bacterial protection against antibiotics are multidrug resistance pumps (MDR), which are involved in the formation of resistance to xenobiotics, the export of toxins, the maintenance of cellular homeostasis, the formation of biofilms and persistent cells. MDR pumps are the basis for the nonspecific protection of bacteria, while modification of the drug target, inactivation of the drug, switching of the target or sequestration of the target is the second, specific line of their protection. Thus, the nonspecific protection of bacteria formed by MDR pumps is a barrier that prevents the penetration of antibacterial substances into the cell, which is the main factor determining the resistance of bacteria. Understanding the mechanisms of MDR pumps and a balanced assessment of their contribution to overall resistance, as well as to antibiotic sensitivity, will either seriously delay the onset of the post-antibiotic era, or prevent its onset in the foreseeable future
Mate choice and size-assortative mating in the climbing perch Anabas testudineus (Actinopteri: Anabantidae)
Authors: Zworykin D.D.
Published: January 2023

Non-random mating plays a key role in speciation and impacts the individual life history. Body size is one of the most important traits by which the mate choice is carried out. Various patterns of body size preference are known in fi sh, but this component of reproductive strategy has been studied in a limited number of species. Although the climbing perch (Anabas testudineus) is widespread and well-known, few descriptions of its spawning have been published, only in captivity and in most cases artifi cially induced with hormonal agents. This paper describes the main features of natural spawning of the climbing perch in aquarium compared to induced spawning. A positive size-assortative mating has been revealed. The mating system of these fish has been shown to be fl exible, presumably ranging from monogamy to polygamy. The results are discussed in the context of the general issue of the adequacy of fi sh behaviour research methods.
Analysis of kefi r grains from diff erent regions of the planet using high-throughput sequencing
Authors: Ding F. , Krasilnikova A.A. , Leontieva M.R. , Stoyanova L.G. , Netrusov A.I.
Published: January 2023

The taxonomic composition and spatial localization of yeast and bacteria in kefi r grains (KG) obtained for study from diff erent regions of the planet were investigated. The diversity of their microbiome has been demonstrated by high-throughput sequencing of bacterial 16S rRNA genes and the ITS1 region of the 18S-ITS1-5.8S-ITS2-28S complex of yeast rRNA. It has been established that the main representatives of the complex community of KG from diff erent regions are lactic acid bacteria (LAB; lactobacilli, lactococci and Leuconostoc spp. in diff erent ratios), and diff erent types of yeast of the genus Kazachstania (family Saccharomycetaceae). Acetic acid bacteria and a small percentage of yeast Kluyveromyces marxianus were detected in the KG from Tibet, and yeast Pichia kluyveri was detected in the KG from Ossetia.
Normal Birth 7. Bringing Birth Home
Authors: Todd Samuel
Published: January 2023

This article looks at the importance of midwives being skilled to attend homebirths, and recent evidence to support the safety of homebirths. It focuses on giving birthing people choices about where to birth safely and highlights the importance of meaningful place of birth discussions. Furthermore, this article discusses the equipment required for a homebirth, how to set up a homebirth and how to ensure a transfer is a safe and a positive experience should this be required.
Understanding Newborn Skin
Authors: Samuels Cheryl
Published: January 2023

The physiology of a newborn baby’s skin is delicate, and it is important to understand how the skin develops in the first few weeks of life and how to care for their sensitive skin. Therefore, careful consideration should be taken when deciding what cleansing agents and products to use on a baby’s skin.
Supporting Complex Homebirths
Authors: Madeley Anna-Marie
Published: January 2023

This article draws on primary research to consider the experiences of midwives who have supported complex homebirths. Unpacking the research findings, midwife and researcher Anna-Marie Madeley provides valuable and nuanced insights from the midwives’ perspectives, across two distinct narratives: ‘antenatal planning and physical intrapartum provision’. Within this context, the notion of the ‘conflicted midwife’ arises, through which we can reflect upon our own experiences and consider how we might navigate delivering such care.
Recto-vaginal fistulas. Recommendations of the Polish Club of Coloproctology Scientific Society
Authors: Kościński Tomasz
Published: January 2023

Recommendations that follow describe the etiology and classification of rectovaginal fistulas and, first and foremost, present the guidelines for surgical management thereof. Techniques used in the management of fistulas located within the lower part of the rectum include fistular lumen resection and layered closure of the resulting tissue loss, including reconstruction of the anal sphincter apparatus. TachoSil collagen-fibrin composite matrix is used to reinforce the reconstructed tissues. In the case of high rectovaginal fistulas, the affected intestinal segment is resected along with the fistular mouth with simultaneous or delayed restoration of gastrointestinal continuity.
100 years of Thorek method - is this technique of breast reduction still actual?
Authors: Kasielska-Trojan Anna , Zieliński Tomasz , Antoszewski Bogusław , Fijałkowska Marta
Published: January 2023

Introduction: In 1922, Max Thorek described the method of breast reduction with the transfer of the nipple–areola complex as free grafts. Initially, this method met with quite a lot of criticism. Therefore, the search for solutions guaranteeing better aesthetic results of breast reduction have been evolved.

 Aim: The aim of the study is to present our own experiences related to the Thorek method of breast reduction in patients with gigantomastia and to consider whether this technique is still relevant in the 21st century.

 Materials and methods: The study included women operated on for large breasts at the Plastic, Reconstructive and Aesthetic Surgery Clinic between 2012–2021. In the analysis 95 women aged 17 to 76 were involved.

 Results: In the analyzed group of 95 women, 14 patients underwent breast reduction with transfer of the nipple-areola complex as a free graft (modified Thorek’s method). In the remaining 81 cases, breast reduction was performed with the transfer of the nipple areola complex on the pedicle (upper-medial – 78, lower – 1, upper-lower – McKissock’s method – 2).

 Conclusion: The usage of Thorek’s method is still actual in a selected group of women. This technique seems to be the only safe one in patients with gigantomastia, with a high risk of nipple-areola complex necrosis related to the distance of nipple transfer, as well as after the end of the reproductive period. Its main disadvantages (tendency to breasts being too wide and flat, unpredictable nipple projection and nipple pigmentation) can be minimized by modification of the Thorek method or minimally invasive follow-up techniques.
Anastomotic Leak in Colorectal Surgery: Predictive Factors and Survival
Authors: Prabhakaran Swetha , Prabhakaran Sowmya , Lim Wei Mou , Guerra Glen , Heriot Alexander  G. , Kong Joseph C.
Published: January 2023

Introduction: Anastomotic leak (AL) is a serious complication following colorectal surgery.

Aim: The aim of this study was to identify factors associated with the development of AL and to analyze its impact on survival.

Materials and methods: All consecutive adult colorectal cancer resections performed between 2007 and 2020 with curative intent and anastomosis formation were included from a prospectively maintained database. The primary outcome measure was the rate of AL. The secondary outcome measure was 5-year overall survival (OS).

Results: There were 6837 eligible patients. The rate of AL was 2.2% and 4.0% in patients with colon and rectal cancer, respectively. AL was a significant independent predictor of reduced 5-year OS in patients who underwent curative surgery for rectal cancer (odds ratio 2.293, p = 0.009). Emergency surgery (p = 0.015), surgery at a public hospital (p = 0.002), and an open surgical approach (p = 0.021) were all associated with a significantly higher risk of AL in patients with colon cancer, with higher rates of AL noted in left colectomies as compared to right hemicolectomies (4.4% vs. 1.3%, p < 0.001). In rectal cancer patients, AL was associated with neoadjuvant chemoradiotherapy (p = 0.038) and male gender (p = 0.002). The anastomosis formation technique (hand-sewn vs. stapled) did not impact the rate of AL (p = 0.116 and p = 0.198 with colon and rectal cancer, respectively).

Discussion: Clinicians should be cognizant of the predictive factors for AL and should consider early intervention for at-risk patients.
First record of Scrobipalpa chrysanthemella (E. Hofmann, 1867) from Poland and new faunistic data on Lepidoptera from Bieszczady National Park
Authors: Paluch Filip , Bodziarczyk Jan , Sosnowski Maciej
Published: January 2023

Scrobipalpa chrysanthemella (E. Hofmann, 1867) was recorded for the first time in Poland. In addition, new data on the occurrence of 13 Lepidoptera species in the Bieszczady National Park are presented. Elachista dimicatella Rebel, 1903 was reported for the first time from Poland outside the Tatra Mountains.
The effect of diflubenzuron (Dimilin® 25 WP) on some non-target aquatic insect and crustacean species
Authors: Serradj Nassima , Bendali-Saoudi Fatiha , Soltani Noureddine
Published: January 2023

The study is aimed at evaluating, under laboratory conditions, the side effects of a commercial formulation of diflubenzuron (Dimilin® 25 WP), which is an insecticide considered a chitin synthesis inhibitor, on some non-targeted aquatic species. The effect of two lethal doses of Dimilin LC10 (3.9 ng/L) and LC50 (16 ng/L) previously determined on fourth instar larvae of Culex pipiens L. 1758 were tested on some non-target aquatic species, abundant in the Lake of Birds (Northeast Algeria), a site classified under Ramsar Convention. The tested species belonged to two classes of invertebrates (Insects and Crustaceans). The insects included four species of Heteroptera: Corixa punctata Illiger, 1807, Notonecta glauca Latreille, 1802, Anisops sardea Latreille, 1802 and Plea minutissima Leach, 1817, and one species of Coleoptera Berosus signaticollis Charpentier,1825. For benthic crustaceans Daphnia magna Straus, 1820 (Cladocera) was retained. The results showed significant mortality recorded in C. punctata and medium mortality for B. signaticollis, A. sardea, N. glauca, P. minutissima and D. magna. Three-way ANOVA indicated highly significant effects of species, dose, and time. According to the sensitivity to Dimilin, the pairwise comparison of Tukey's test indicates that the most sensitive species was C. punctata followed by B. signaticollis and the least sensitive was N. glauca, followed by D. magna; then A. sardea and finally P. minutissima.
Clinical significance of Left-Sided Gallbladder for laparoscopic cholecystectomy and hepatectomy
Authors: Szymoniuk Michał , Brachet Adam , Ciejka Karol , Zielkowska Alicja , Błaszczyk Jan , Burdan Oliwia , Baj Jacek
Published: January 2023

Introduction: A left-sided gallbladder (LSG) represents a rare anatomical variation defined by the location of the gallbladder to the left side of the liver falciform and round ligaments, which is often not discovered until surgery. The reported prevalence of this ectopia ranges from 0.2% to 1.1%.

Aim: To summarize the knowledge about LSG and possible coexisting anatomical anomalies, and discuss the clinical significance of the LSG when the patient requires cholecystectomy or hepatectomy.

Methods: Comprehensive review of existing literature from the years 2012–2022 based on PubMed, Scopus, and Web of Science databases.

Results and discussion: Using standard diagnostic procedures, LSG can remain undetected and represent an accidental intraoperative finding. The attempts to explain the cause of this anomaly have been different, but the numerous variations described do not allow a clear definition of its origin. Although this debate is still open, it is of considerable importance to know that LSG is frequently associated with alterations of both the portal branches and the intrahepatic biliary tree. The association of these anomalies, therefore, represents an important risk of complications in cases when surgical treatment is necessary. The knowledge of LSG and coexisting anatomical variations of the hepatobiliary system, and finally the introduction of suitable technical modifications can be of considerable help in preventing surgical complications in patients with LSG.

Significance: This article summarizes existing knowledge about LSG and coexisting anatomical anomalies, whose occurrence can hamper standard procedures such as laparoscopic cholecystectomy or hepatectomy. These findings can be essential and helpful in treating patients with detected LSG to decrease the risk of surgical complications.
Etiología de las infecciones gastrointestinales y el diagnóstico de laboratorio: Prevalencia actual.
Authors: Wilson Acebo Dayanara Betzabeth , Campozano Villacreses Joisa María , Zambrano Macías Coralía
Published: January 2023

En la infección invasiva se produce un cuadro inflamatorio difuso, a veces acompañado de necrosis del epitelio y ulceraciones de la mucosa, con pequeños abscesos que dan lugar a la liberación de sangre con gran cantidad de polimorfonucleares y de líquido, incapaz de ser absorbido a causa de la destrucción celular ocasionada por el microorganismo. Esta investigación tuvo un diseño documental, el tipo de estudio es descriptiva, bibliográfica. La herramienta para la recolección de los datos consistió en la realización de una búsqueda de diferentes documentos bibliográficos de carácter científicos en las bases de datos Google académico, PubMed y Scielo.En la presente investigación tuvo como resultado entre las manifestaciones clínicas de los pacientes que padecen infecciones gastrointestinales se deben en gran parte a agentes microbianos se análisis que todos los pacientes 37 (21%) presentaban clínica sugestiva de síndrome de intestino irritable, 26 (15%) de síndrome de intestino irritable más síndrome dispéptico y en 24 (14%) de síndrome dispéptico. Mediante la investigación bibliográfica que las principales infecciones gastrointestinales fueron: Clostridium difficile, Escherichia coli, Escherichia coli O157:H7, Helicobacter pylori, Rotavirus, Salmonella y Shigella. En este se puede concluir que existió gran prevalencia de tener infecciones intestinales parasitarias.
Los factores de riesgo del síndrome TORCH y su prevalencia en mujeres gestantes de América Latina.
Authors: Avila Delgado Suanny Mishelle , Palma Mendieta Paulina Daniela , Piguave Reyes José Manuel
Published: January 2023

El síndrome de TORCH, se caracteriza por agrupar un grupo de infecciones de trasmisión sexual, en la que se incluye la toxoplasmosis, rubéola, citomegalovirus, sífilis, hepatitis b, entre otras, estás suelen estar presente por diversos factores entre ellas la más frecuente es tener varias parejas sexuales a la vez por lo que conlleva un riesgo grave, sobre todo en el embarazo ya que puede transmitirse de manera vertical al feto o al momento de nacer, provocando  así consecuencias desfavorables a ambas partes. El objetivo de esta investigación fue analizar los factores de riesgo del síndrome TORCH y su prevalencia en mujeres gestantes de américa latina. El diseño metodológico que se aplicó fue documental, descriptivo permitiendo la recolección de artículos relacionados con la problemática. Los resultados mostraron que dentro de América Latina los factores de riesgo más prominentes son tener varias parejas sexuales, la edad, y el uso de sustancias ilícitas, se puede enfatizar que una de las infecciones en mujeres gestantes con más prevalencia fue la toxoplasmosis, manifestando así que las consecuencias más relevantes dentro del síndrome de TORCH son las malformaciones congénitas, abortos, y nacimientos prematuros entre otro, se llegó a la conclusión de que la prevalencia del síndrome de TORCH en mujeres gestantes en América Latina fue mayor en Venezuela para el 2012, seguido de Colombia, Bolivia, Uruguay y Ecuador presentando toxoplasmosis congénita.
The inhibitory activity of Ruxolitinib against COVID-19 major protease enzyme and SARS CoV-2 spike glycoprotein: A molecular docking study
Authors: DEMİRAG A. Demet , ÇELİK Sefa , ARSLAN Samet , ÖZEL Ayşen , AKYÜZ Sevim
Published: January 2023

Ruxolitinib (C17H18N6) is a Janus kinase (JAK) inhibitor that inhibits JAK1, JAK2, and JAK3 and with its tyrosine kinase inhibitor function It is the first drug approved for use in the treatment of myelofibrosis. The possible conformations of the ruxolitinib molecule were searched using PM3 technique and the Spartan06 software. The estimated molecular energies of the Ruxolitinib conformers, obtained by the variations in dihedral angles, were compared, and the most stable conformer was determined. To enlighten the inhibitory activity of Ruxolitinib agaist the apo (PDB ID: 6M03) and holo (PDB ID: 6LU7) forms of the main protease enzyme (Mpro) of COVID-19 and the SARSCoV-2 spike glycoprotein (PDB ID: 6VXX), molecular docking simulations were performed. The binding affinities and binding modes were determined. The binding free energies of ruxolitinib and 6M03, 6LU7, 6VXX targets calculated by the combination of Molecular Mechanics/Generalized Born Surface Area (MMGBSA) and Molecular Mechanics/Poisson-Boltzmann Surface Area (MM-PBSA) methods {MM/PB(GB)SA approach}, were found to be -22.24, -19.96 and -22.44 kcal/mol, respectively.
A study on the method to visualize the product development cycle by predicting patent applications for each product
Authors: Hayashi Yoshinori , Masuda Koji , Haruyama Shigeyuki
Published: January 2023

Knowing the growth process of a company's business and products is a valuable insight for innovation. While launching the first product is a prerequisite for innovation, the process after the launch of the first product is equally important. In many cases, a business is finally established after several generations of product launches. In this study, we show a method to visualize the product development cycle of each generation by predicting the transition of the number of patent applications for each product. Furthermore, as part of the discussion, we apply this method to Seiko Epson projector products and demonstrate that our results were valid. We observed that Seiko Epson repeats the product development cycle in the growth process of its projector business and products. Based on the findings, we discuss the method's applicability to the analysis of a company's business and product growth
Methodological strategies to strengthen the teaching-learning process in basic education children
Authors: López Pérez Tannia Elizabeth , Manzano Pérez Renato Sebastián , Manzano Pérez Rodrigo Javier , Zumbana Herrera Lilian Fabiola
Published: January 2023

Game-based teaching and learning methodological strategies are tools that help transform learning into an interactive activity in the classroom, so this educational-social learning experience provides the elements of education. Practical-practical actions can be taken in teacher-student interactions to create meaningful environments with meaning. learning. The objective of this study was focused on identifying the incidence of the use of methodological strategies to reinforce the teaching-learning process in basic education children by combining data collected between 2018 - 2022. A descriptive, non-experimental documentary method was carried out. through a bibliographic review of different scientific articles and studies related to the subject from 2018 to 2022. The results obtained from the bibliographic review according to several authors mention that methodological strategies benefit the teaching-learning process in students and it is one of the very important factors to improve the quality of teaching and the diffusion of learning styles among students. From this study it is concluded that the incidence of methodological strategies was identified to reinforce the teaching-learning process in children. It is of the utmost importance for both the student and the teacher to have strategies to teach the classes and the children can develop their cognitive learning, psychomotor and linguistic