bluuebunny/crossref_metadata_2025 huggingface dataset:
Синфітоіндикаційна оцінка едафотопів лісових екосистем за даними моніторингу лісів лісостепової частини України
Authors: Bondaruk M.A. , Tselischev O. G.
Published: June 2022

Проведено синфітоіндикаційне оцінювання едафотопів лісових екосистем Лісостепової лісогосподарської області України. Визначено тенденції динаміки середніх значень показників едафічних режимів лісових екосистем згідно зі змінами лісорослинних умов. Система моніторингових досліджень лісів має охоплювати моніторинг едафічних режимів екотопів лісових екосистем поряд із кліматичними (методами прямих вимірювань та методами синфітоіндикації). Порівняння отриманої балової оцінки в різні часові періоди (наприклад, раз на 5 років) в кожному регіоні України дасть змогу оцінювати інтенсивність, глибину, спрямованість (тренд), просторовий розподіл та особливості зміни едафічних режимів на регіональному та національному рівнях унаслідок дії глобальних кліматичних впливів на лісові екосистеми України, що є важливою складовою моніторингу лісових екосистем в умовах зміни клімату. Об’єкти досліджень – 642 ділянки моніторингу лісів І рівня (представлено 49 типів лісу в 15 типах лісорослинних умов: А1–А3, В1–В3, С1–С4, D1–D5) у межах Лісостепової лісогосподарської області України.
Вікові дерева житлових масивів Києва як залишки колишніх соснових лісів
Authors: Klimenko A. V.
Published: June 2022

Метою досліджень було виявлення вікових дерев сосни звичайної на території Дніпровського району для внесення до додаткових реєстрів-довідників об’єктів природної спадщини в Києві. На території, де проводили досліди, залишилося 258 вікових і майже 100-річних дерев сосни звичайної (середня висота 18–20 м, стан задовільний). Запропоновано надати особливий охоронний статус віковим соснам як об’єктам природної спадщини та внести їх до реєстрів-довідників охорони вікових дерев як ботанічні пам’ятки природи України. Визначено доцільну черговість відновлення соснових насаджень досліджуваного району м. Києва, влаштування лісових і лісопаркових зон сосни звичайної.
The Security of the Russian Federation and the National Legal System
Authors: Vladimir Valentinovich Kozhevnikov
Published: June 2022

In the article, considering one of the most controversial concepts in the theory of law, as a national legal system, it is substantiated that such negative legal phenomena as contradictions in law, its gaps, legal nihilism, etc., should not be included as structural elements of legal system, because the latter is the result of the activity of the state, created to solve its goals and objectives, acting as one of the most important aspects of the sovereignty of the state, which, in turn, is the main subjects that ensure national security.
Hemoglobin A1c Value of Pregnant Diabetic Women with Their Neonatal Outcome
Authors: Saha Debashish , Sharker Suman , Jahan Ismat , Shabuj Md Kamrul Hasan , Moni Sadeka Choudhury , Dey Sanjoy Kumer , Shahidullah Md , Mannan Md Abdul
Published: June 2022

Background: HbA1c is now accepted as a standard measure for diagnosing type 2 diabetes mellitus. Maternal high HbA1c levels have been associated with increased risk of adverse neonatal outcomes.
Objective: To find out the relationship between maternal HbA1c and neonatal outcomes.
Materials & Methods: This prospective observational study was conducted from February 2018 to January 2019 in the Department of Neonatology and Department of Gynecology & Obstetrics, BSMMU, Dhaka. Diabetic mothers with known HbA1c Value and their infants who were born in this study period in BSMMU were enrolled. Neonates were divided into two groups. One group that had maternal HbA1c <6% and the other group >6%. Neonatal weights, routine capillary blood glucose were recorded.
Results: Among the total 94 mothers, HbA1c level were <6% in 56 mothers and ³6% in 38 mothers. The mean weight, BMI and previous history of gestational diabetes of mothers were significantly higher in HbA1c ³6% group. Birth weight and large for gestational age infants was high in ³6% HbA1c group. Neonatal hypoglycemia developed more in high HbA1c group. Total visible birth defect was 4 and all were in high HbA1c group (p=0.022).
Conclusion: Elevated HbA1c level during pregnancy is a predictor for large for gestational age infants as well as neonatal hypoglycemia.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (2) : 74-78
Dyslipidaemia Among Bangladeshi Children and Adolescents with Type-1 Diabetes: An Observational Study
Authors: Baki Abdul , Zabeen Bedowra , Islam Nasreen , Nahar Jebun , Azad Kishwar
Published: June 2022

Introduction: Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D).

Materials & Methods: This cross-sectional study was aimed to evaluate the frequency of dyslipidaemia and its association with other risk factors in children and adolescents with type 1 diabetes. A total of 397 Type 1 diabetes (T1DM) patients aged 10-18 years who attended, Paediatric diabetes clinic in BIRDEM over one year period were included in this study.

Results: The overall frequency of dyslipidaemia was 63.5% and median duration of diabetes was 3.0[2.0- 5.0 years]. The High LDL was most cmmmon dyslipidaemia (81%) in our study population. FBS was significantly higher 12.8[10.0-15.5] vs 10.8[7.7- 12.6] (p<0.0001)) and higher median HbA1c 9.9 [8.5-11.9] vs 9.0[7.9-10.5] (p<0.0001)) was found in dyslipidaemic patients. Median systolic blood pressure was higher (110 vs100) in dyslipidaemic patients ( p =.042).

Conclusion: The frequency of dyslipidemia was high among the children and adolescents with T1DM which was associated with poor glycaemic control. Our results provide strong support for prior literature in emphasizing the importance of good glycemic control, to reduce the risk of dyslipidaemia.

BANGLADESH J CHILD HEALTH 2021; VOL 45 (2) : 79-82
Frequency and Risk Factors of Seizures in Children During Induction Remission Chemotherapy for Acute Lymphoblastic Leukemia (ALL)
Authors: Soma Shahinoor Akter , Jamal Chowdhury Yakub , Chowdhury Indira , Diba Farah , Saha Mousumi
Published: June 2022

Background: Seizure is one of the most common CNS complications among patients receiving chemotherapy for acute lymphoblastic leukemia (ALL). Seizures are seen in 8-13% of patients with ALL. Most seizure occurs during the induction and consolidation phases of treatment. However, not much is known about the risk factors of these seizure.

Materials & Method: This prospective observational study was conducted in the department of Pediatric Hematology and Oncology, BSMMU. One hundred and five newly diagnosed admitted children with ALL aged >1 year to <18 years, from May 2017 to March 2018 for induction remission chemotherapy and who fulfilled the criteria of case definition were enrolled into this study.

Results: This study showed that seizure frequency was14.3% in children with ALL getting induction remission chemotherapy. Female patients developed seizures more than males which was statistically significant by univariate analysis (p = 0.029) but was not found to be a risk factor by multivariate analysis (p = 0.059). All the seizures developed in B-lineage ALL but there was no statistically significant association between lineage of ALL with development of seizures.

Conclusions: In this study slightly higher frequency of seizure in ALL patients on induction remission chemotherapy was found than previous studies (14.3% vs. 13%). Females developed seizures more than males.

BANGLADESH J CHILD HEALTH 2021; VOL 45 (2) : 94-98
Marfan Syndrome in Two Sibs: A Case Report
Authors: Chowdhury Kona , Ahmed Mesbah Uddin , Uddin Mohammed Jamal , Roy Sudipta
Published: June 2022

Marfan syndrome (MFS) is a rare inherited disorder of connective tissue characterized by various phenotypical and genetic manifestations. It involves mutation in FBN1 gene which encodes for microfibrillin glycoprotein fibrillin-1. Predominant involvement occurs in eyes, skeleton and cardiovascular system. Cardiovascular abnormalities such as aortic root dilatation and mitral valve prolapse are the two main life-threatening complications associated with MFS. The diagnosis is based upon clinical findings, some of which are age dependent. If not properly treated, premature death may be caused by the severe cardiovascular and pulmonary complications associated with Marfan syndrome. Therefore, it is important to identify this potentially life-threatening condition in general practice. We are presenting two cases of Marfan syndrome from same family due to its rarity.

BANGLADESH J CHILD HEALTH 2021; VOL 45 (2) : 108-110
Generalized Hyperpigmentation - An Unusual Feature in Neurologic Wilson Disease: Report of Two Cases
Authors: Islam Rumana , Kundu Gopen Kumar , Akhter Shaheen , Anwar Anjir
Published: June 2022

Wilson disease also known as hepatolenticular degenerationis an autosomal recessive disorder of copper metabolism, usually presents either with hepatic or neurological features. But sometimes along with common features, some atypical presentations may also co-exist. We report here two cases of Wilson disease, a 15 years old girl and 14 years old boy presented with some neurological manifestations along with gradual darkening of whole body.

BANGLADESH J CHILD HEALTH 2021; VOL 45 (2) : 124-127
Efflux Pump Inhibitory Potential of Vitexin 2"-O-xyloside Against Gram Positive Bacteria Staphylococcus aureus
Authors: Munira Sirazum , Zaman Shadid Uz , Muhit Md Abdul
Published: June 2022

Expression of bacterial efflux pump is one of the major causes for developing antibiotic resistance in a variety of pathogens. Efflux pump inhibitors (EPIs) are potential molecules that can antagonize those pumps and help in alleviating the resistance problem. The study was aimed to explore the EPI activity of vitexin 2"-O-xyloside, an apigenin flavone glycoside. A total 15 clinical isolates of Staphylococcus aureus were collected and their antibiotic resistance profiles were detected by Kirby-Bauer disc diffusion assay and MIC values were determined through broth microdilution technique. Prevalence of efflux pump activity were examined through ethidium bromide agar-cartwheel method. Fractional inhibitory assay was carried out in combination with tetracycline and ciprofloxacin against clinical isolates of S. aureus with efflux pump activity. Finally, molecular docking approach was carried out in the active binding sites of NorA efflux pump protein by Autodock Vina. All of the clinical isolates showed resistance to cefixime, ciprofloxacin and tetracycline antibiotics whereas all of them were sensitive to chloramphenicol. Efflux pump was found active among 20% of the clinical isolates. The tested compound showed additive effective (ƩFIC value 0.625 – 0.75) when co-treated with tetracycline in the efflux pump active isolates which was similar to reserpine. Molecular docking studies showed that vitexin 2"-O-xyloside may bind to the different binding sites, opening the door for it to be considered as a potential EPI.
Dhaka Univ. J. Pharm. Sci. 20(3): 307-315, 2022 (June) Centennial Special Issue
Evaluation of Dissolution Behavior of Cefuroxime Axetil as Affected by Polymeric Interaction Using Mixture Design Experiment
Authors: Faisal Khandokar Sadique , Bhuiyan Mohiuddin Ahmed , Al Mamun Md Elias
Published: June 2022

The objective of this project was to improve the solubility of poorly water soluble drugs, namely cefuroxime axetil by formulating solid dispersions with hydrophilic polymer. Hydroxypropyl methyl cellulose (HPMC), polyvinyl pyrrolidine (PVP) and polyethylene glycol (PEG) were used as polymeric carriers for the preparation of solid dispersion. Solid dispersions were prepared by the solvent extraction method. Interaction effect of HPMC, PVP and PEG was investigated using a simplex mixture design. A fitted mathematical model was used to express each response as a function of the proportion of the blend components that are able to empirically predict the response to any blend of combination of the components. The synergistic interaction effect of the ternary HPMC: PVP: PEG blend was shown to be strongest among the experimental blends. Nevertheless, an antagonistic interaction effect becomes significant as the HPMC proportion increases in the blends. The study revealed that a mixture design could be a valuable tool in better elucidating and predicting the effects on dissolution beyond the conventional one component blend.
Dhaka Univ. J. Pharm. Sci. 20(3): 317-324, 2022 (June) Centennial Special Issue
Development, Characterization and In vitro Evaluation of Solid Dispersion Formulations of Low Aqueous Soluble BCS Class II Drug Pitavastatin with Poloxamer 407 and HPMC
Authors: Mikrani Ishtyaque , Sarkar Md Raihan , Islam Mehedi , Das Sreedam C , Rahman Prattay Kazi Milenur
Published: June 2022

This study was aimed to boost up the dissolution rate of a sparingly aqueous soluble BCS Class II drug pitavastatin (PTV) by solid dispersion (SD) techniques using two hydrophilic polymers poloxamer 407 and hydroxypropylmethylcellulose (HPMC). Low aqueous solubility of PTV is associated with less oral bioavailability, and a real challenge in preparing appropriate dosage form. To enhance the aqueous solubility, physical mixing and SD formulations of PTV were developed by fusion and solvent evaporation methods using two hydrophilic polymers, poloxamer 407 and HPMC. Scanning electron microscopy (SEM) investigation indicated that PTV molecules were homogeneously dispersed in carrier prepared by different formulation methods at 1:2 and 1:3 ratios of PTV: polymer assuming amorphous SD state. The thermogravimetric profiles demonstrated that PTV was stable up to 198°C and began to decompose rapidly with significant weight loss as the temperature was raised over 190°C. Formulations prepared by SD techniques were stable at high temperature. In vitro studies illustrated that cumulative drug release of PTV: HPMC/poloxamer 407 formulations prepared by physical mixing, fusion and solvent evaporation techniques were better compared to pure PTV powder (61.42±0.91%). Among all the approaches, formulations prepared by solvent evaporation and fusion methods displayed higher cumulative releases of PTV than physical mixing formulations. The results of current study clearly indicated that PTV: HPMC/poloxamer 407 (1:2) formulations (S3, S1) developed by solvent evaporation method possess enhanced dissolution profile (96.06%; 95.62%) than the fusion SD formulations (F3; 94.62%, F1; 87.05%). Whereas PTV physical mixing formulations (P2; 82.32%, P4; 80.28%) containing high amount of carrier polymers (ratio 1:3) exhibited superior in vitro dissolution rates than formulations (P3; 68.70%, P1; 71.52%) having less quantity (ratio 1:2) of HPMC/poloxamer 407. It is apparent from the findings of this study that SD formulations (S3, S1, F3, F1) of PTV with HPMC/poloxamer 407 is a very promising approach for improving the in vitro dissolution profile of the sparingly aqueous soluble PTV. Moreover, 1:2 ratio formulations prepared by fusion and solvent evaporation SD approaches were found more effective to upgrade the release rate of PTV than the 1:3 formulations.
Dhaka Univ. J. Pharm. Sci. 20(3): 325-336, 2022 (June) Centennial Special Issue
Lipid-Based Nanocarriers for Oral Delivery of Proteins and Peptides: Opportunities, Challenges, and Future Prospects
Authors: Naim Jannatul , Sharmin Nahid , Shuma Madhabi Lata , Halder Shimul
Published: June 2022

Oral administration is the most common drug delivery route with high levels of patient acceptance. However, oral delivery of therapeutic proteins/peptides is extremely difficult, and improving the pharmacological bioavailability still is a challenging goal because of the poor membrane permeability, high molecular weight, and enzymatic degradation of these drugs. Lipid-based nanocarriers represent a viable means for enhancing the oral bioavailability of protein or peptide drugs while minimizing toxicity. Nowadays, like other macromolecules protein or peptide drugs are the promising candidates to be delivered employing liposomes and lipid nanoparticles including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC). Generally, these drug delivery strategies can reduce protein or peptide drug degradation and improve membrane permeability thus enhance bioavailability. This review demonstrates various lipid-based formulation strategies used for successful oral delivery of peptides and proteins, assesses the hurdles and delivery efficiency and their clinical implications.
Dhaka Univ. J. Pharm. Sci. 20(3): 395-416, 2022 (June) Centennial Special Issue
Työkalu broilerituotantotilojen hiilijalanjäljen hallintaan
Authors: Palander Samu , Taijala Beata , Teittinen Henri
Published: June 2022

Ruoantuotantoon liittyvät mahdollisuudet Suomen kokonaishiilipäästöihin vaikuttamiseen ovat rajalliset. Maatalouden osuus valtakunnallisista hiilipäästöistä (global warming potential –suhteutettuina kaasuina, joista osa ei liity kemiallisesti hiileen) on yleisten tulkintojen mukaan noin kymmenen prosenttia. Hiilipäästökeskustelussa on kuitenkin kiinnitetty paljon huomiota kotieläintuotteisiin ja niiden osuuteen tuotannossa tai ravinnossa. Elintarviketeollisuuden toimijat ovat julkistaneet viime vuosina maidontuotantoon ja lihantuotantoon liittyviä, selkeästi mielikuvaa parantamaan tarkoitettuja hankkeita hiilipäästöjen laskemiseksi ja alentamiseksi. Broilerituotannossa rehunmuuntosuhde ja sitä kautta ekologinen tehokkuus verrattuna muuhun kotieläintuotantoon on hyvä, vaikkakin tuotanto edellyttää suhteellisen arvokkaita rehuja. Lisäksi kanalintujen ruoansulatuksen metaanipäästöjä voidaan pitää merkityksettömän pieninä. Broilerituotannossa on lisäksi mahdollisuuksien mukaan pyritty etsimään uusiakin ratkaisuja rehuvalinnoissa ja lämmitysenergiassa, ja näillä voidaan hiilijalanjälkeen tai ylipäänsä ympäristökuormitukseen vaikuttaa. Hiilijalanjälkilaskuri broileritiloille –hankkeessa on kehitetty tilatason työkalua näiden valintojen merkityksen arviointiin tai seurantaan. Tarkastelu rajattiin tässä tuotantopolven broilerien kasvatukseen. Tausta-aineistona on hyödynnetty Luonnonvarakeskuksen raportteja tai muita valtakunnallisia tiedon tuottajatahoja, kuten Motivaa tai Lipasto-tietokantaa. Hiilijalanjälkilaskureissa on aina haasteena laskennan rajaamisen ja yleistettävyyden ongelma. Hallitustenvälinen ilmastonmuutospaneeli (IPCC) on julkaissut joitakin laskentaperiaatteita, joita broileritilojen hiilijalanjälkilaskurissakin on hyödynnetty. Vaikka tavoitteena on ennen muuta tilatason valintojen vaikutuksen demonstroiminen, on kuitenkin pyritty yleisestikin vertailukelpoisia tuloksia antavaan laskentaan. Laskennassa on kuitenkin tehty joitakin tarkoituksellisia yksinkertaistuksia vertailukelpoisuuden parantamiseksi nimenomaisesti kehitystyössä mukana olevan yrityksen muussa yhteydessä laskettuihin tuloksiin. Laskurissa päädyttiin huomioimaan sähkö, lämmitysenergia ja muu energiankulutus, rehut, kuivikkeet sekä lannan käsittely ja varastointi suhteutettuina tuotettua ruhokiloa kohti. Laskurin testaaminen hankkeen yhteistyö- ja kohdetiloilla on mahdollistanut merkittävimpien päästölähteiden (rehu, energia) tunnistamisen sekä laskurin muokkaamisen käytettävyydeltään ja informatiivisuudeltaan tarkoituksenmukaiseksi. Laskentaa voidaan myös verrata muihin jossain määrin vertailukelpoisiin laskureihin ja niiden antamiin tuloksiin.
PERBANDINGAN KUALITAS BAHAN BAKAR DARI PENGOLAHAN SAMPAH PLASTIK MENJADI BAHAN BAKAR MINYAK DENGAN METODE PIROLISIS
Authors: Mustam Mariaulfa , Ramdani Nurfika , Syaputra Irfan
Published: June 2022

Given the existence of plastic waste in the environment is very dangerous, therefore it is necessary to conduct research to handle it. The development of technology for plastic processing to produce something useful continues to be carried out by various groups, ranging from scientists, academics, and students. One of them is the utilization of plastic waste into fuel oil (BBM) using the pyrolysis technique which will be installed to process plastic waste. The purpose of this study was to determine the fuel oil from processing plastic waste and compare the fuel with kerosene and diesel oil with the parameters of density, burning time and water temperature when heating using the three fuel oils. The research method used is data collection techniques including pre-treatment, the process to determine the density of each fuel sample, the process of burning time, temperature during heating, analysis of the density of pyrolysis oil, kerosene and diesel fuel by measuring the volume and the mass of each sample. Comparison of the quality of Fuel Burning Time, namely Oil from recycled plastics 4.01 minutes, Diesel Oil 4.45 minutes, and Kerosene 3.02 minutes. Comparison of the quality of water temperature with a volume of 20 ml of water and a heating time of 5 minutes, it is found that recycled plastic oil is 0.77oC, diesel oil is 0.73oC, kerosene is 0.84oC. plastic waste processing is under kerosene but above diesel oil based on density indicators, burning time, water temperature when heating.
RANCANG BANGUN AUTOMATIC HAND WASHING STATION DENGAN MENGGUNAKAN MIKROKONTROLLLER ARDUINO UNO R3
Authors: Djafar Alfian , Kentjana Muhammad Gilang , Kristiyanto Reza , Afudin Yusuf
Published: June 2022

Washbasin needs to be provided in a place that is generally visited by people. It is necessary to design an automatic hand washing machine to reduce direct contact. This study aims to design and manufacture a simple automatic hand washing device, using a microcontroller and equipped with sensors to regulate the faucets and also regulate the release of the soap dish. This research has 3 stages. The first stage of planning includes the selection of actuators, sensors, and microcontrollers. Second, the manufacture of tools in the form of mechanical manufacture, electrical circuits, and programming. The final stage is testing, responding to tools that will function properly, and monitoring those that still need to be developed. Based on the research, the Automatic Hand Washing Station design tool uses a frame in the form of steel angles with holes SA75 3.75 x 3.75 with binders in the form of Hex Bolt and Nut M10, Arduino Uno R3 Microcontroller, Relay Module, Buck Converter, 2 Infrared Sensors, 5 LEDs, the actuators used are Single pump DC 12V 4.5A, servo motor 9.4 kgf.cm, reservoir with a capacity of 19 liters, and Power Adapter 12V 5A. The electronic system affects the performance of the actuator which results in the less functioning of the actuator itself. This connected obstacle is caused by the condition of the jumper cables that accumulate and also the less than the optimal output power. The programming system uses the Arduino IDE and can run well in the simulation tool process.
STUDI KOMPARASI KANDUNGAN TIMBAL PADA BUAH APEL (Malus domestica) VARIETAS FUJI DARI PASAR TRADISONAL DAN SWALAYAN DI YOGYAKARTA
Authors: Sambo Minarsih Maria , Prihatmo Guruh , Aditiyarini Dwi
Published: June 2022

This study aims to determine and compare the concentration of Pb in Fuji apples from traditional markets and supermarkets. Samples were obtained from the outer Demangan market, the outside and inside Kranggan market, Superindo and Mirota Kampus. Samples were extracted using aqua regia HCl: HNO3 (3:1, v/v). Analysis of Pb concentration using Atomic Absorption Spectrophotometer (AAS). Data processing using SPSS with ANOVA test to determine the ratio of Pb concentration from each location. The average concentration of Pb in Fuji apple samples was obtained from the Demangan outside market (0.213 mg/kg), Kranggan outside market (0.208 mg/kg), Kranggan inside market (0.162 mg/kg), Superindo (0.147 mg/kg) and Mirota Campus (0.168 mg/kg). Based on the BPOM quality standard (2018), the concentration of lead in the outer Demangan market and the outside Kranggan market has passed the quality standard. As for the quality standard of SNI (2009) all concentrations are still within safe limits. So from the results of this study it can be said that the sales location is important to the lead content in Fuji apples, especially those sold near the highway, this is indicated by the highest lead concentration sourced from open sales locations and close to the highway, that is Kranggan outside market and the Demangan outside market. The treatment of washing fuji apples also showed a decrease in lead levels in fuji apples.
PENGARUH KONSENTRASI EKSTRAK BIJI DAN KULIT BUAH PINANG (Areca catechu L.) TERHADAP MORTALITAS LARVA NYAMUK Aedes aegypti
Authors: Noya Anjela , Rahardjo Djoko , Cantya Prakasita Vinsa
Published: June 2022

The purpose of this study is to determine the potential extract of areca nut (Areca catechu L.) seeds, skin and the combination of the two extracts in killing the Aedes aegypti larvae. This study used a Completely Randomized Design in the seed extract test with a concentration of 16000, 17000, 18000, 19000 and 20000 ppm and skin extract with concentrations of 7000, 8000, 9000, 10000 and 11000 ppm. The factorial design was used in the combined extract of 0:100; 25:75; 50:50; 75:25 and 100:0. Each treatment used 4 replications.  Data were analyzed by ANOVA and then continued by Tukey, LSD and Duncan tests. The last, data were analyzed by probit analysis to determine LC50 and LC90. The result indicates that areca nut seed and skin contain flavonoid, alkaloid, palmitic acid, phenols, terpenoids and steroids which are toxic. The killing power of seed extract was 64-97% (24hours) and 100% in all treatments (48hours). Skin extract was 52-88% (24hours) and 58-93% (48hours), while the combination extract was 55 -93% (24hours) and 95-100% (48hours). Concentration of 19000 ppm of seed extract with 95% mortality at 24 hours was effective when compared to the WHO standard (2005), while the skin extract had a lower LC value than the other two extracts.
GHOSTING DALAM PEMBELAJARAN ONLINE: SEBUAH PERSPEKTIF DARI SISI TUTOR
Authors: Kismiati Dyah Aniza , Ucu Rahayu  , Mery Novianti  , Zakirman  , Yos Sudarso
Published: June 2022

The Covid-19 pandemic caused many significant changes in the learning system. By the implementation of online learning policies, it raises its own problematics until the emergence of ghosting phenomena in learning. The ghosting phenomenon is seen as the inactivity of students in online learning. This study is a type of quantitative descriptive research using survey method with a sample of 1,974 tutors at the Open University. The data was collected through questionnaire instruments shared online with tutors. The questionnaire instrument is an open question and there is also a likert scale. As a support, also conducted interviews with several tutors. The sampling technique used is a random sampling technique. The results of this study inform that 94.43% of tutors have experienced the phenomenon of ghosting carried out by students while 5.57% stated that there is no ghosting phenomenon in online learning. Of the 94.43% who stated the occurrence of the ghosting phenomenon, 31.05% of them think that ghosting is a phenomenon of student inactivity in online learning (not responding when called and invited to discuss), 20.62% of other tutors believe the same thing even admits that the ghosting phenomenon is common in online learning, other tutors also revealed some things related to ghosting in online learning. Thus, learning strategies are needed to overcome the phenomenon of ghosting in online learning.
ANALISIS KEMAMPUAN BERPIKIR GEOMETRI BERDASARKAN TAHAP BERPIKIR VAN HIELE PADA PEMBELAJARAN MATEMATIKA SISWA SMP
Authors: Kurnia Aulidia Nauval , Nita Hidayati
Published: June 2022

Geometry is a mathematical branch that deals with the shape of an object, the spatial relationship between various objects, and its properties. Learning geometry is essential to supporting logical thinking ability, perceptual intuition, and reading and interpreting mathematical arguments. But many middle school students do not reach the stage of deduction and precision. The research was to analyze a high school student's geometry ability based on Van Hiele's stages of thinking. They consist of five levels of visualizing, analysis, sequence, deduction, and precision. It is a type of qualitative study with a descriptive method. The sample consisted of 20 eighth-graders in the located in the Karawang district. Data collection is carried out using a written questionnaire and test. Research shows that stage-0 (visualization) is the student's most achievable point from a questionnaire at 55% and a written test of 65%. The third stage (deduction) and fourth (accuracy) are the most difficult for students to achieve, based on written tests only 9% of students reach the third stage and only 6% of students reach the fourth. Student difficulties in learning this geometry may be due to several factors in their understanding of prerequisite materials, ability to concepts and pale-building qualities is lacking, and limited skill in using geometry ideas to solve mathematical problems.
Effect of ischemia and reperfusion on protein oxidation in isolated rabbit hearts.
Authors: Tatarková Z , Kaplán P , Matejovičová M , Lehotský J , Dobrota D , Flameng W
Published: June 2022

Reactive oxygen species and other oxidants are involved in the mechanism of postischemic contractile dysfunction, known as myocardial stunning. The present study investigated the oxidative modification of cardiac proteins in isolated Langendorff-perfused rabbit hearts subjected to 15 min normothermic ischemia followed by 10 min reperfusion. Reperfusion under these conditions resulted in only 61.8+/-2.7 % recovery of developed pressure relative to preischemic values and this mechanical dysfunction was accompanied by oxidative damage to cardiac proteins. The total sulfhydryl group content was significantly reduced in both ventricle homogenates and mitochondria isolated from stunned hearts. Fluorescence measurements revealed enhanced formation of bityrosines and conjugates of lipid peroxidation-end products with proteins in cardiac homogenates, whereas these parameters were unchanged in the mitochondrial fraction. Reperfusion did not alter protein surface hydrophobicity, as detected by a fluorescent probe 1-anilino-8-naphthalenesulfonate. Our results indicate that oxidation of proteins in mitochondria and possibly in other intracellular structures occurs during cardiac reperfusion and might contribute to ischemia-reperfusion injury.
Leptin, soluble leptin receptor and leptin gene polymorphism in relation to preeclampsia risk.
Authors: Muy-Rivera M , Ning Y , Frederick IO , Vadachkoria S , Luthy DA , Williams MA
Published: June 2022

Few investigators have simultaneously evaluated leptin, soluble leptin receptor (SLR) and leptin gene polymorphisms in preeclampsia cases and controls. We examined these three biomolecular markers in 40 preeclampsia cases and 39 controls. Plasma leptin and SLR concentrations were determined using immunoassays. Genotype for the tetranucleotide repeat (TTTC)(n), polymorphism in the 3 -flanking region of the leptin gene was determined using PCR. Alleles of the polymorphism were characterized by size distributions [short repeats (class I); and long repeats (class II)]. Logistic regression was used to calculate odds ratios (OR) and 95 % confidence intervals (CI). Leptin concentrations were higher in our cases than in the controls (53.1 4.7 vs. 17.7+/-2.4 ng/ml, p<0.05). SLR concentrations were slightly lower in our patients than in the controls (25.7+/-1.9 vs. 29.1+/-1.1 ng/ml, p>0.05). Elevated leptin (? 14.5 ng/ml) was associated with a 3.8-fold (CI 1.0-14.4) increased risk; whereas low SLR (< 28.5 ng/ml) was associated with a 6.3-fold (CI 1.7-23.2) increased risk of preeclampsia. The I/II genotype was associated with a 3.8-fold increased risk of preeclampsia (OR=3.8; 95 % CI 0.8-18.0); and the II/II genotype was not observed among our cases (0 % vs. 33 % p<0.001). Larger studies would be needed to confirm and further clarify the relations between functional variants in the leptin gene and preeclampsia risk.
KUALITAS PELAYANAN ADMINISTRASI TERHADAP KEPUASAN DAN LOYALITAS MAHASISWA MENGGUNAKAN STRUCTURAL EQUATION MODELING DI FAKULTAS TEKNIK
Authors: - Nurlaily - , Susilawati Tri , Alfaruqi Muhammad Hilmy
Published: June 2022

Membahas Tentang Pengaruh Kualitas Pelayanan Administrasi terhadap Kepuasan dan Loyalitas Mahasiswa menggunakan Structural Equation Modeling di Fakultas Teknik. Metode penelitian menggunakan kuantitatif deskriptif dengan menggunakan kuesioner sebagai penilaian mahasiswa. Pengujian menggunakan structural equation modeling (SEM) yang menunjukkan hasil bahwa kualitas pelayanan memberikan pengaruh positif dan signifikan terhadap kepuasan mahasiswa. Sedangkan kepuasan mahasiswa juga memiliki pengaruh positif dan signifikan terhadap loyalitas mahasiswa. Kualitas pelayanan tidak berpengaruh positif secara langsung terhadap loyalitas mahasiswa. Sedangkan dimensi atau item-item yang harus ditingkatkan dalam kualitas pelayanan adalah Tangibles dan Assurance. Oleh karena itu perlu dilakukan peningkatan terhadap variabel yang menyebabkan terciptanya kepuasan dan loyalitas mahasiswa dengan inovasi yang dapat dilakukan pihak fakultas seperti menyediakan alur pelayanan, memberikan kemudahan kepada mahasiswa untuk memperoleh akses informasi dengan selalu melakukan update terhadap website maupun sosial media lainnya, memanfaatkan penggunaan Sistem Informasi Administrasi dengan menyediakan pedoman penggunaan atau manual book dari sistem tersebut.Kata-kata Kunci: Kualitas pelayanan, Kepuasan mahasiswa, Loyalitas Mahasiswa
STUDI DESKRIPTIF KUALITATIF: MOTIVASI MELAKUKAN PUBLIC DISPLAY AFFECTION PADA PENGGUNA MEDIA SOSIAL TIKTOK
Authors: Putri Ainaya Pradina , Alamiyah Syifa Syarifah
Published: June 2022

Masyarakat Indonesia khususnya para remaja sudah semakin akrab dengan perilaku pacaran. Bahkan, saat ini mereka tidak ragu untuk menunjukkan kemesraan atau romantisme mereka di media sosial seperti Tiktok. Romantisme yang dilakukan bersama pasangan ditunjukkan dalam konten video yang dibuat dan disebarkan secara publik dimana siapa saja ti tentukan. Hasil penelitian menunjukkan informan melakukan PDA di media sosial Tiktok untuk memenuhi kebutuhan akan hubungan (relatedness’s needs) yaitu mendapat penerimaan positif dari pengguna Tiktok lainnya dan penerimaan positif dari orang-orang disekitar informan seperti keluarga dan teman-teman. Selain itu, informan juga berhasil memenuhi kebutuhan akan keberadaan (existence’s needs) yaitu mendapatkan pengdapat mengakses video tersebut termasuk remaja bahkan anak-anak. Sementara catatan kekerasan di Indonesia memiliki persentase yang tinggi akibat perilaku pacaran. Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan motivasi remaja melakukan public display affection di media sosial Tiktok menggunakan teori kebutuhan dan motivasi dari Clayton Alderfer. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Sedangkan pengumpulan data dilakukan melalui wawancara mendalam dan dokumentasi terhadap empat informan yang telah penelihasilan dari tawaran endorsement produk, menghilangkan rasa takut akan kehadiran orang ketiga dalam hubungan informan serta menghilangkan rasa takut pasangan tidak mau mengakui atau merasa malu memiliki pacar seperti diri informan, dan kebutuhan akan pertumbuhan (growth’s needs) yaitu keinginan informan untuk terus belajar mengembangkan kreativitas dan ide-ide untuk dituangkan dalam konten-konten informan. Kata Kunci: Motivasi, Public Display Affection, Tiktok
Factorials and Integers for Applications in Computing and Cryptography
Authors: Annamalai Chinnaraji
Published: June 2022

Mathematical formulae with integers or prime numbers are used as cryptographic algorithms like RSA algorithm and elliptic-curve cryptography. These methodological advances in computational science and mathematics play a vital role in communication and cybersecurity. This article is prepared for applications in computing and cybersecurity using the theorems in factorials and binomial identity. Also, this paper focuses on the analysis of relationship between factorials and integers.
Oncology Social Work and Interprofessional Education (IPE): Analysis of Multidimensional Competencies
Authors: Smith Sky
Published: June 2022

This article compares the education competencies of the social work professional in the United States with standards related to interprofessional education. The analysis maps the Council on Social Work Education (CSWE) Educational Policies and Accreditation Standards (EPAS) (2015) to the competencies of the Interprofessional Education Collaborative (IPEC, 2016). The additional lens of oncology health care disparities is used to emphasize the added educational needs of oncology social workers to participate in and lead interprofessional medical teams in the oncology field.
Perfil jornalístico como gênero textual no contexto escolar: uma análise da linguagem avaliativa
Authors: Bueno Emanuelle Tronco , Fuzer Cristiane
Published: June 2022

A partir do entendimento de que textos são produto da interação social, materializadas na escrita aberta e dialógica, este artigo analisa como a linguagem avaliativa se apresenta nos textos produzidos por estudantes a partir de uma proposta de produção de perfil jornalístico em sala de aula. A pesquisa está fundamentada na abordagem Sociorretórica de gênero textual e no sistema de Avaliatividade da Linguística Sistêmico-Funcional. Foram analisados cinco textos do gênero perfil jornalístico em suas versões finais produzidos por alunos de uma turma de 2º ano de uma escola pública em Restinga Sêca, no Rio Grande do Sul, a partir de uma proposta de produção de perfil jornalístico como gênero textual. A análise evidenciou o uso de recursos avaliativos que expressam, principalmente, julgamentos positivos acerca dos perfilados, seguidos por expressões de afeto e apreciação. As ocorrências de avaliação utilizadas nos textos produzidos pelos estudantes contribuem para caracterizar a natureza autoral do perfil jornalístico.
A inclusão social de gênero em ações de divulgação científica de museus de ciências
Authors: Silva Anelissa Carinne dos Santos , Da Silva Camila Silveira
Published: June 2022

O presente artigo se apoia no Estudo de Caso para apresentar a análise de entrevistas de coordenadoras dos projetos Meninas com Ciência (Museu Nacional) e Meninas no Museu (Museu de Astronomia e Ciências Afins1), em uma perspectiva da inclusão social de gênero. No recorte explorado, foi analisada a categoria emergente intitulada de Impactos dos Projetos, orientada pela Análise de Conteúdo fundamentada pelos referenciais teóricos de Estudos de Gênero e Divulgação Científica em Museus. Os resultados evidenciaram a potencialidade dos dois projetos para a inclusão social de gênero por meio de ações para a inserção de meninas em atividades de mediação e debates que resultaram em percepção positiva sobre pertencimento, sororidade, dentre outros.
A percepção da violência de gênero e a transmissão geracional em mulheres que sofrem violência doméstica
Authors: Conte Raquel Furtado , Von Mühlen Bruna Krimberg
Published: June 2022

O presente estudo propõe-se a refletir acerca da contribuição dos dispositivos de sexualidade e geração para a compreensão da percepção da violência de gênero em mulheres que vivenciaram essa experiência. A partir de entrevistas com 24 mulheres, as pesquisadoras investigaram a violência entre as gerações e a sua percepção sobre essa experiência. As entrevistas foram gravadas e transcritas e o referencial de análise foi o de conteúdo. As bases teóricas utilizadas foram a psicologia sistêmica e a psicanálise. Os resultados apontaram para os padrões de comportamentos que as mulheres repetem, a partir da transmissão multigeracional e da atribuição da feminilidade com a maternidade e o lugar de esposa. As conclusões revelaram que as mulheres ainda precisam resistir ao não desejo e à manutenção do lugar de escravas de seu destino.
Avaliação das aprendizagens no ensino da sociologia escolar: uma análise a partir dos livros didáticos de sociologia do Ensino Médio
Authors: Pires Welkson , Marques Arimax
Published: June 2022

Este trabalho tem por objetivo pensar os processos de avaliação das aprendizagens no ensino escolar das Ciências Sociais a partir das proposições presentes nos livros didáticos de Sociologia do ensino médio, aprovados no PNLD 2018. Decidimos abordar essa temática focalizando livros didáticos por entendermos que tais obras emergem como o fenômeno educacional que melhor sistematiza as disciplinas escolares, norteando, em grande medida, o processo de ensino e aprendizagem. Por meio desses livros didáticos, buscamos detectar, descrever e classificar os objetivos de aprendizagem, as propostas avaliativas e os instrumentos de verificação da aprendizagem empregados na Sociologia Escolar. Com isso, pudemos apreender, mediante à análise de conteúdo de tais livros, o modo como se configura e algumas das especificidades da avaliação no ensino das Ciências Sociais em nível médio.
Dizeres sobre o curso de linguística geral: acontecimento e recepção na história da linguística brasileira
Authors: Ruiz Marco Antonio Almeida , Araújo Lígia Mara Boin Menossi de
Published: June 2022

O CLG traduz uma mudança de paradigma nos estudos linguísticos do início do século XX. Sua contribuição é tão grande que o consideramos como um acontecimento histórico marcante nas ciências humanas e sociais, capaz de promover o que ficou conhecido como Linguística moderna. Com o advento de novas perspectivas que emergiram após a década de 1960 na França, passamos a compreender o processo de recepção de suas teorias e revisitá-las novamente como acontecimentos discursivos que (re)contam, cada um a sua maneira, narrativas de sua história e (re)formulação. Assim, propomos observar, numa perspectiva discursiva, a constituição do manual Fundamentos da linguística contemporânea, de Edward Lopes, como um acontecimento discursivo que produz, a nosso ver, um efeito de didatização da teoria saussuriana durante a emergência da linguística brasileira.
Recontextualização de concepções de aprendizagem nos âmbitos governamental e escolar
Authors: Kummer Daiane Aline , Arnt Janete Teresinha
Published: June 2022

O objetivo deste trabalho é identificar princípios subjacentes a perspectivas que fundamentam concepções de aprendizagem nas Diretrizes Curriculares Nacionais para o Ensino Médio (BRASIL, 2012). A partir disso, verificamos possibilidades de recontextualização desses princípios em atividades de ensino de inglês em livros didáticos. A análise do documento foi realizada a partir da identificação de itens linguísticos (BARTON, 2004) que fizessem referência a tais perspectivas. Os resultados evidenciam um alinhamento do documento à perspectiva sociocultural e a possibilidade de uma transposição dessa perspectiva no contexto escolar a partir de atividades de livros didáticos discutidos no estudo, o que contribui para a promoção de um ensino contextualizado que estimule a conscientização do estudante.
Educação e Democracia: Gênero e Sexualidade em tempos de “Escola sem Partido” Entrevista com Fernando Seffner
Authors: Rossi Jean Pablo Guimarães , Pátaro Ricardo Fernandes
Published: June 2022

Esta entrevista foi cordialmente concedida pelo professor Fernando Seffner em abril de 2019 nas dependências da Universidade Estadual do Paraná – UNESPAR/Campus de Campo Mourão, por ocasião de palestra proferida por Seffner durante a Aula Magna do Mestrado Profissional em Ensino de História (ProfHistória) com o tema “Democracia, Escola e Ensino de História”. As reflexões realizadas por Seffner nesta entrevista versam sobre questões de gênero, sexualidade e o movimento auto denominado Escola Sem Partido (ESP). Diante dos embates políticos da atualidade, Fernando Seffner discute a respeito da liberdade de ensinar e aprender e reflete sobre a relevância de perspectivas pós-estruturalistas, estabelecendo um paralelo com outras/os autoras/es que também fazem parte deste campo científico. Ao fim da entrevista, Seffner deixa um convite a todas e todos que desejam lutar em defesa de um ensino laico, plural e democrático, explanando acerca do Movimento Ação Educação Democrática, no qual tem se engajado atualmente. O Ação Educação Democrática é organizado pela Associação Nacional de Pós-Graduação e Pesquisa em Educação (ANPEd), em parceria com o Movimento Educação Democrática.
PONCIÁ VICÊNCIO E A LITERATURA NA EDUCAÇÃO BÁSICA REVIVIFICANDO RAÍZES AFRICANAS
Authors: Lima Alyne Barbosa , Mesquita Rodrigo
Published: June 2022

Neste artigo, procura-se, a partir da obra Ponciá Vicêncio, de Conceição Evaristo, discutir questões relativas à inclusão da temática "História e Cultura Afro-Brasileira" no âmbito da educação básica, tal como preconiza a Lei nº 10.639/03. Para tanto, no contexto específico de uma escola pública de Jataí, Goiás, buscou-se observar os impactos do processo de aprendizado e tomada de consciência cultural por intermédio da literatura negra, tal qual a obra de Conceição Evaristo. A metodologia contemplou a realização de um estudo de caso, que inclui o trabalho de campo para coleta de dados, nos moldes de uma pesquisa-ação, em que dois grupos de alunos tiveram os resultados comparados. O primeiro deles, composto por alunos que tiveram contato com a obra Ponciá Vicêncio e/ou que frequentavam projetos específicos da escola para o cumprimento da lei 10.639/03, demonstrou maior conscientização e interesse pela temática “História e Cultura Afro-Brasileira" do que os alunos do segundo grupo, que não tiveram contato com obra de Conceição Evaristo e tampouco participavam dos projetos. Ademais, uma proposta de análise da obra Ponciá Vicêncio, a partir de seus personagens e que foi utilizada durante a pesquisa-ação, é oferecida como subsídio para sequências didáticas na educação básica.
REPRESENTAÇÕES E IDENTIDADES JUVENIS NA SOCIEDADE ATUAL: PADRONIZAÇÕES E ESTEREÓTIPOS
Authors: Lima Crislaine Pereira de , Polato Adriana Delmira Mendes , Pátaro Cristina Satiê de Oliveira
Published: June 2022

A partir de uma abordagem interdisciplinar, que coaduna interpretações da sociologia, da antropologia, da filosofia e do dialogismo do círculo russo de Bakhtin, nosso objetivo consiste em analisar um artigo intitulado “Os jovens nem nem” publicado na revista “Istoé” online, que mobiliza um discurso sobre os jovens que não estudam e também não trabalham. Na análise do enunciado, buscamos compreender como ele reflete e refrata valorações próprias de partidas ideológicas que buscam analisar o papel social do jovem a partir de uma interpretação de base socioeconômica. Os conceitos de signo ideológico, palavra, ideologia, e consciência socioideológica são mobilizados na análise, na medida em que entendemos que o enunciado é constituído por valorações que sustentam relações sociais, interpretações de mundo e das vivências, sempre a partir de posicionamentos ideológicos. Como resultado, apresentamos a importância do dialogismo na análise dos discursos que ecoam perspectivas sócio-históricas, culturais e ideológicas sobre a temática das juventudes, a destacar como fundamental a presença de vozes sociais e valores que servem a representações refratárias, ou à multiplicidade de identidades e trajetórias dos jovens, de modo a clarificar  como os discursos  constituem e ao mesmo tempo são constituídos pelas relações sociais, sendo sua interpretação subsidiária de prospecções e rupturas de ordens instaladas.
THE IMPACTS OF LEARNING TO READ ON BRAIN ACTIVITY AND A SOCIOCULTURAL VIEW ON HUMAN COGNITIVE FUNCTIONING: A POSSIBLE RELATION
Authors: Agnoletto Matheus André , Tomitch Lêda Maria Braga
Published: June 2022

Abstract: the present paper has a threefold objective: (i) to present a sociocultural view on human mental functioning; (ii) to review studies on the impacts of learning to read on brain activity; and (iii) to draw a parallel between a vygotskian view on human cognition and neuroscientific evidence of how learning to read impacts brain activity. The studies reviewed show the ways reading acquisition results in changes in brain activity, as well as how the brain reorganizes itself in order to accommodate new functions as a response to this process. From a vygotskian instance, this illustrates how one’s cognitive development is fostered on the external plane as they interact with socioculturally constructed means.