bluuebunny/crossref_metadata_2025 huggingface dataset:
Experiencias en el uso de la Realidad - Virtual
Authors: Chiroque Landayeta Víctor Enrique
Published: June 2024

El presente trabajo aborda el uso de la realidad virtual en el contexto educativo y describe la evolución de las experiencias inmersivas a lo largo de los años. Asimismo, resalta los desafíos y oportunidades de la implementación de la realidad virtual en los procesos de enseñanza y aprendizaje.
Dicotomías en el diseño: subjetividadobjetividad vs formalidad-utilidad
Authors: Sánchez Yván J. , Kobashigawa Zaha Ysabel S. , Kobata Luis Alva
Published: June 2024

Este escrito aporta una reflexión sobre las relaciones que existen entre arte, ciencia, diseño e ingeniería desde una perspectiva epistemológica a partir de la matriz de Rich Gold.
Spatial matching of emergency shelters to the distribution of residents in the light of transport behaviours of evacuees during war: the case of Suwałki
Authors: Borowska-Stefańska Marta , Goniewicz Krzysztof , Grama Vasile , Horňák Marcel , Masierek Edyta , Morar Cezar , Pénzes János , Rochovská Alena , Turoboś Filip , Wiśniewski Szymon
Published: June 2024

The aim of the article was the assessment of the spatial matching of existing shelters (supply) to the distribution of residents in Suwałki (demand), considering their declared transport behaviours while evacuating during war. The analysis was conducted based on the locations of existing emergency shelters using data on population distribution (registration data with building accuracy). Spatial alignment was determined using the P-Median problem and E2SFCA. In terms of establishing vehicular or pedestrian travel time, the Manhattan metric based on the urban road network model was utilised. A model of vehicle movement speed was then constructed, while a constant speed was assumed for pedestrian movement. Additionally, survey data on the transport behaviour of inhabitants of Suwałki in the case of war were conducted in 2023. The study concluded that the population residing within the city limits should evacuate on foot, and that prior training on the evacuation process is especially necessary for those who reside in less populated areas of the city. The analyses also showed that existing emergency shelters are overly dispersed, making management difficult for emergency services. Since the current capacity of emergency shelters is not sufficient for the number and distribution of inhabitants of Suwałki, the most practical significance of this article in this respect is to indicate to the authorities the optimal number and location for emergency shelters (to improve the evacuation process).
A FOTOGRAFIA E SEU POTENCIAL ARTÍSTICO
Authors: De Souza Thalita Emanuelle , Fonseca da Silva Maria Cristina da Rosa
Published: June 2024

O presente artigo tem como principal objetivo entender a condição do olhar fotográfico atual e como ele se relaciona com o ambiente que nos cerca e cerceia a sociedade e por consequência a escola, de forma crítica e estética fundamentada na pedagogia histórico-crítica. A principal questão deste texto é: como o ensino de artes visuais, por meio da fotografia, pode ampliar a visão estética dos estudantes e do ser social, a partir do seu entorno? Para respondê-la, fundamentei-me na pedagogia histórico-crítica de Demerval Saviani.
GRIS: A INTERSEÇÃO E A DUALIDADE ENTRE OS JOGOS E A ARTE
Authors: Elias dos Santos Rafael
Published: June 2024

Este artigo tem por objetivo tentar responder uma questão em debate atualmente: se os jogos eletrônicos podem ser considerados uma forma de arte. Para isto, foi construída uma noção de arte pautada na estética e o conceito de jogo foi emprestado de Huizinga (2004). Ademais, foram examinados argumentos de artigos sobre o tema e feita uma análise do jogo Gris (Nomada Studio, 2018), que possui elementos estéticos. A principal conclusão é de que é desafiador afirmar que os videogames são arte, embora compartilhem elementos, e que, talvez, o cerne deste debate seja outro: a validação do jogo como forma cultural relevante. Além disso, parece necessário que os jogos e a arte permaneçam distintos, pois uni-los eliminaria a singularidade do jogo.
O QUE É UM TÚNEL?
Authors: De Souza Antonio Wagner , De Fátima Berguenmayer Minuzzi Reinilda
Published: June 2024

O presente artigo resgata o artista que atravessa um túnel extenso e desconhecido na região central do Rio Grande do Sul. Confronta suas impressões e propõe reverberações no audiovisual através do tempo. Espaço e técnica entrecortada pelo olhar frente ao desconhecido, o artista que entra desgovernado em direção ao artista que sai do túnel. Túnel, metalinguagem da luz que atravessa a objetiva na câmera, que retorna luz no fim do túnel e imagem digital nas telas e displays. Sobreposição de tempo digital consumindo memória eletrônica sobre tempo percorrido, transposto. Objeto da arte que foge ao que é a proposta, emergência que supera o imaginado, vida que não segue qualquer roteiro. O relato de experiência presente nessas linhas é um exercício de retorno ao túnel, decomposição de seus elementos e associação dessas unidades a um repertório videográfico, que pretende, vislumbrar algo semelhante ao futuro. Voltar a um túnel transposto como quem pretende que ele termine em outros lugares. Vença distâncias tangíveis e intangíveis. O artista que faz da realização videográfica performance incidental e busca na repetição a poética capaz de revelar outros trajetos através de tuneis ainda não descobertos. Para finalmente se perguntar: o que é um túnel?
Hermann Kantorowicz i Theodor Viehweg przeciwko pozytywizmowi prawniczemu
Authors: Chmielecki Jan Zygmunt
Published: June 2024

Celem artykułu jest opisanie istoty Hermanna Kantorowicza i Theodora Viehwega teoretycznego odniesienia wobec pozytywizmu prawniczego. Dwie kluczowe prace opisane w artykule to H. Kantorowicza Walka o naukę prawa (1906) i Th. Viehwega Topika i jurysprudencja (1974). Artykuł porównuje teoretyczne nastawienie dwóch wspomnianych badaczy wobec pozytywizmu prawniczego do negacji paradygmatu naukowego opisanego przez Thomasa S. Kuhna. Artykuł zawiera refleksje metodologiczne. Autor krótko ustala, co to jest pozytywizm prawniczy. Według autora H. Kantorowicz negował pozytywizm prawniczy z perspektywy podobnej do protestantyzmu. Uznawał, że osoba określająca prawo musi niejako „ewoluować” i stać się „samo-świadoma”. Teoria Th. Viehwega podkreśla, że niemożliwym jest traktować prawo jako skończony, logiczny system. Uważał on, że prawo powinno być traktowane jako suma topoi, czyli jako raczej rozwiązujące konkretne problemy niż zmierzające do uformowania wspomnianego systemu.
Charakter prawny powołania na stanowisko dyrektora Instytutu Sieci Badawczej Łukasiewicz
Authors: Baraniecki Maciej
Published: June 2024

Przedmiotem niniejszego opracowania naukowego jest powołanie dyrektora instytutu Sieci Badawczej Łukasiewicz na gruncie regulacji ustawy o Sieci Badawczej Łukasiewicz oraz analiza jego charakteru w oparciu o Kodeks Pracy. Celem artykułu jest rozwiązanie problemów interpretacji poszczególnych przepisów ustawy dotyczących łączenia stosunku pracy oraz wymaganej w procesie powołania umowy o zarządzanie instytutem Sieci.
Odpowiedzialność wspólnika przystępującego do spółki cywilnej za istniejące zobowiązania
Authors: Ślusarek Tomasz
Published: June 2024

Tematem pracy jest odpowiedzialność wspólnika przystępującego do spółki cywilnej za jej zobowiązania w momencie przystąpienia wspólnika do spółki. W spółce cywilnej odpowiedzialność za zobowiązania jest w głównej mierze warunkowana przez art. 864 k.c. Tytułowa kwestia jest sporna w doktrynie prawa, jak i w orzecznictwie sądowym, również ze względu na wątpliwości co do możliwości zmiany składu osobowego wspólników spółki cywilnej. W pracy rozważono kilka możliwych stanowisk, ze szczególnym uwzględnieniem dorobku doktryny prawa. Następnie wskazano na argumentacje uzasadniającą (w ocenie autora) ponoszenie odpowiedzialności przez przystępującego wspólnika spółki cywilnej za istniejące zobowiązania spółki cywilnej w momencie jego przystąpienia.
Determinanty zachowań nabywców na rynku usług turystycznych — w świetle badań
Authors: Herbik Emilia
Published: June 2024

Przedsiębiorcy funkcjonujący na rynku usług turystycznych muszą wykazywać się nie tylko elastycznością w dostosowywaniu się do preferencji grupy odbiorców, lecz także troską o budowanie trwałych relacji z klientami. Celem pracy jest identyfikacja determinant zachowań konsumentów korzystających z usług biur podróży w Polsce. Artykuł oparty jest na analizie danych statystycznych dostępnych w bazach światowych (Statista) oraz krajowych (CBOS, Ipsos Polska, dane Ministerstwa Sportu i Turystyki), oraz na badaniach pierwotnych przeprowadzonych w celu rozpoznania determinant zachowań konsumentów korzystających z usług biur podróży na rynku usług turystycznych,. Badania zostały zrealizowane na próbie 156 respondentów od grudnia 2022 do września 2023 roku. Badania wykazały rosnącą popularność usług biur podróży w Polsce oraz dominującą rolę ceny jako głównej determinanty wyboru oferty turystycznej touroperatora. Ponadto zaobserwowano istotną rolę marketingu szeptanego i opinii użytkowników w procesie podejmowania decyzji przez klientów oraz wzrost znaczenia mediów społecznościowych w promocji usług turystycznych.
ISLAMIZATION CONSUMPTION BEHAVIOR CONCEPT (ISLAMIC OFFER IN CONSUMPTION BEHAVIOR IN THE ALFA GENERATION)
Authors: Hakim Muhamad Arief Al , Umam Khoirul , Yaqqin Aynul , Trigiyatno Ali , Muhtarom Ali
Published: June 2024

The current needs system is no longer determined by real needs but has been regulated with the existence of commodity goods. Society's system of consumption changes rapidly to follow the system of needs so that the consumption of goods and services is no longer a necessity but a desire of every individual who is swept up in the consumptive world. Consumerism culture is considered a culture that must be attached to society in order to obtain an identity. Even though the Prophet Muhammad and his companions, preferred to give infaq fi sabilillah, even well waqf by Utsman Bin Affan, rather than simply consuming a commodity that was not useful and did not spend their wealth on something without benefit, especially for an impossible lifestyle, including using their wealth in moderation. This study uses the literary method to search for various literature sourced from journals and books that have to do with consumerism, consumption, and consumption behavior. The results of the study explain that consumerism which is based on the principles of utilitarianism and rationality alone, encourages consumers to maximize use value without regard to human values and even Islamic values, as a result, creates individualism and self-interest. There are at least 5 points that need to be implemented in Islamic offers in consumption behavior, including 1) Paying attention to priority scales in consuming a commodity, 2) Following Islamic norms in consumption behavior, 3) Maintaining Maqoshid Syariah with the aim of benefiting individuals and society, 4) Comply with the principles of halal and haram, 5) Consumption behavior is part of increasing worship.
CONSUMER PROTECTION IN BEACH TOURISM OBJECTS FROM THE PERSPECTIVE OF MAQASHID SHARIA (STUDY IN THE SUB-DISTRICT OF MIRROR BEACH, SERDANG BEDAGAI DISTRICT)
Authors: Trihafsari Wiwik , Permata Cahaya
Published: June 2024

Activities in tourist attractions pose a risk of danger for tourists, which can impact safety and security, including beach tourism. It must be backed by infrastructure that promotes safety and security in these tourist locations to reduce current risks. Visitors' rights to safety, security, and clear information are guaranteed by Law No. 8 of 1999 on consumer protection and Law No. 10 of 2009 on tourism, specifically Article 20. This study aims to investigate how the Pantai Cermin District's beach attractions' facilities, their consumer protection policies, and the notion of consumer protection as seen through the lens of Maqashid Sharia. This study employs a conceptual framework, a statute-based methodology, and an empirical case-study approach to the law. The results of this study indicate that the facilities at beach attractions in Pantai Cermin Subdistrict still need to fulfil safety and security aspects, such as the unavailability of health clinics, watchtowers, and luggage storage for tourists. In the perspective of maqashid sharia, consumer protection of security and safety in beach tourism is the application of the principles of Hifz al-Nafs (protecting the soul) and Hifz al-Mal (protecting property), so beach tourism managers must provide security, health, and safety facilities for beach visitors.
IMPLEMENTATION OF PUBLIC SERVICE REFORM IN ENHANCING THE WELFARE OF BIMA DISTRICT COMMUNITY: CHALLENGES AND OPPORTUNITIES
Authors: Satika Renni , Salahuddin  , Kasman  , Suraya
Published: June 2024

This study examines the implementation of public service reforms in Bima District with the goal of enhancing community welfare. Utilizing a qualitative and descriptive approach, primary data were gathered through in-depth interviews with local stakeholders, while secondary data were sourced from policy documents and statistical reports. Thematic analysis was employed to categorize findings based on research objectives. Results show positive changes like improved health service accessibility and quality. However, challenges persist in management, service standards compliance, and policy alignment with community needs due to bureaucratic rigidity and lacking leadership. The research concludes that while reforms have benefits, there's substantial room for improvement, particularly in management, transparency, and service delivery innovation. It emphasizes the need for strong commitment across government levels to drive innovation, address infrastructure and human resource barriers, and enhance institutional coordination, thereby directly impacting community welfare in Bima District.
OBSTACLE OF COVID-19 DIGITAL SURVEILLANCE AT PUBLIC HEALTH CENTERS: EXPLORATORY STUDY IN WEST JAVA
Authors: Heriana Cecep , Binti Moh Said Faridah , Yasmin Farzana
Published: June 2024

Background: The quality of COVID-19 data from surveillance information systems is still an issue in low-middle-income countries (LMIC), including Indonesia, which uses various applications that have the potential to affect surveillance performance. Purpose: To explore the procedures and obstacles to using various digital surveillance applications at Public Health Centers (PHCs) in Indonesia. Methods: Qualitative research with exploratory studies was used.  The setting was in the PHC in Kuningan, Majalengka, and Indramayu, City of Cirebon, Indonesia, with surveillance officer participants and contact tracer data manager, as many as 8.  Data was collected by interviewing and using snowball sampling techniques between May 12 and 20, 2022. Data were analyzed using content analysis. Results: The initial data collection procedure involves obtaining data from various health facilities.  Data recording was with SILACAK and the New All-Recorded application.  Data analysis with descriptive epidemiology was reported to the head.  Data quality was achieved with monitoring.  Obstacles in data collection were rejection, community paradigm, and fear. The obstacles of the application are maintenance, not immediately updating that day, not entering at that time, sometimes it does not run smoothly, there are no tools for visualization, and data distribution per place not yet available. Conclusion: In COVID-19 surveillance procedures, from initial data collection, data recording, data analysis, data reporting, and data quality assurance, there are obstacles to data collection in the community and to applications used for surveillance. The District Health Office must compile new procedures that include data management stages, epidemiological data analysis, and visualization.
SOCIOECONOMIC INEQUALITIES, WATER, SANITATION, HYGIENE AND DIARRHEAL DISEASE AMONG CHILDREN UNDER FIVE YEARS IN INDONESIA
Authors: Astutik Erni , Tama Tika Dwi
Published: June 2024

Background: Diarrheal diseases are still a serious digestive tract infection in Indonesia. The geographical areas with lower socioeconomic inequalities and water, sanitation and hygiene (WASH) contribute to incline diarrheal disease among children under 5 years old. Purpose: This study aimed to map the distribution of diarrheal diseases among children under 5 years old and identify areas with higher risk in socioeconomic status and WASH. Methods: This study used secondary spatial data repository from Indonesia Demographic Health Survey 2017. This study used ecological approach to provide visual geographic distribution of diarrheal diseases among children under 5 years old, as well as to identify the risk based on the socioeconomic inequalities and WASH. The map production was performed by GIS software. Results: We found that provinces with higher percentage of diarrheal diseases in children also had higher percentage of population with the lowest socioeconomic status. Additionally, the provinces which had higher unimproved drinking water sources, unimproved sanitation facility, and limited handwashing facility, had the higher percentage of diarrheal disease among children under 5 years. Conclusion: The percentage of the lowest socioeconomic status and unimproved WASH might contribute to incline the percentage of diarrheal disease among children under 5 years. The government needs to consider the geographical area to decrease the diarrheal diseases among children under 5 years.
DOMINANT RISK FACTORS FOR THE INCIDENCE OF “ACUTE RESPIRATORY INFECTION” “ARI” IN TODDLERS
Authors: Ginting Johannes Bastira , Anggraini Nazila , Syukriyah Syaputri Pasaribu Bella , Nur Rehan , Buenita Buenita
Published: June 2024

Background: Acute Respiratory Infection (ARI) is a contagious illness affecting diverse age groups, including toddlers, and is among the top ten reasons for Community Health Center visits. Purpose: This study aims to analyze the influence of dominant risk factors on the incidence of ARI in toddlers. Methods: This study used an observational, analytic-cross sectional approach, at Puskesmas Kampung Lalang, Medan, in 2023. The total population was 394 toddlers (aged 0-59 months).  In the determination of the number of samples using the sample size estimation formula, 198 samples were obtained by purposive sampling. Data analysis used Chi-Square test and Multiple Logistic Regression Enter Methods, with a significance level of 95%. Results: The results showed that the variables of Vitamin A administration (OR = 0.27, 95% CI: 0.10-0.77) and immunization status (OR = 0.36, 95% CI: 0.14-0.93) were associated with a decreased risk of ARI in toddlers. In contrast, exclusive breastfeeding (OR = 2.35, 95% CI: 1.11-5.01) was associated with increased risk, while the physical environment of the house (OR = 2.92, 95% CI: 1.28-6.64) was associated with increased risk of ARI. Conclusion: Vitamin A administration and immunization reduce the risk of respiratory tract infection among under-fives at Puskesmas Kampung Lalang. Exclusive breastfeeding and home conditions increased the same risk. Improving these risk factors is essential to reduce the prevalence of childhood respiratory infections in the area.
The Evolution of Germany`S Political and Military Influence in the Near East
Authors: Trunov F.
Published: June 2024

The situation in the Near East is important for each power, especially for the rising one. Germany belongs to the last category. The article tries to explore the forms, features and results of the FRG`s usage of political and military tools in the Near East by the mid‑2020s. For two decades, Germany was trying to become security and stability provider for regional actors, to ensure strategic influence in the zones of armed conflicts. But in Iraq and especially in Syria, the results of Berlin’s participation in the struggle against the “Islamic state” (Terrorist organization banned in Russia) were rather modest. Hence, the Bundeswehr was forced to short its presence in Iraq and to reduce it to zero in Syria by the early 2020s. Rather important for Germany was the critical lack of opportunities to influence over growing strategic activity of the key regional actors. The FRG has faced the fact of distancing with Turkey which demonstrated its special position from other Western democracies on many regional issues. In 2010s, Germany made significant efforts to relieve tensions around Iran (because of its nuclear program and the confrontation with Saudi Arabia), but in the early 2020s, Berlin turned to the containment of this country. There has been also the disruption of the previous balance in the development of Germany’s partnership with Israel, Jordan, Palestinian National Authority, and Lebanon (official Beirut). Berlin starts to see the relations with Tel-Aviv as the highest priority. All the tendencies have received noticeable development during the war in the Gaza Strip since October 2023.
The “Pivot to Asia”: AUKUS in the Perception of American Politicum
Authors: Golub Y. , Shenin S.
Published: June 2024

The article is devoted to forecasting the ways of further evolution of the Western partnership called AUKUS, taking into account the geopolitical plans of J. Biden administration, and based on an analysis of the approaches of the most influential groups among the American political elite to the project. In the context of the American strategy “Pivot to Asia”, differences in views of these groups on the content of AUKUS and its prospects are shown. Special attention is paid to the study of the American experts’ and politicians’ ideas about the potential of using nuclear submarines in the Indo-Pacific region by Australia with regard to “containing” China, as well as technological cooperation between the partnership member countries in order to expand a common industrial base. While the Conservative Republicans believe that it is necessary to focus only on creating a fleet of submarines for Australia (the “first pillar”), Conservative Democrats and Moderate Republicans demand to concentrate exclusively on technological cooperation not merely of the three AUKUS countries (the “second pillar”), but also attracting other players to it – Japan, New Zealand, South Korea, Canada. Only the Centrist Democrats, who are the most loyal supporters of the administration, are confident that the alliance countries will be able to “pull through” the implementation of both “pillars” of the project. The authors underscore that the coalition of the “second pillar” looks preferable today. It is concluded that the radical divergence of the elite groups’ views makes the future fate of the AUKUS quite uncertain, and the partnership can acquire different configurations depending on the balance of forces within the U.S. political establishment.
Utilization of Artificial Intelligence in Breast Pathology
Authors: Baclig Michael
Published: June 2024

In the last decade, artificial intelligence (AI) has been increasingly used in various fields of medicine. Recently, the advent of whole slide images (WSI) or digitized slides has paved the way for AI-based anatomic pathology. This paper set out to review the potential integration of AI algorithms in the workflow, and the utilization of AI in the practice of breast pathology.
Hackear los cuerpos.
Authors: Amaya Velasco Hermann Omar
Published: June 2024

In 1953, DNA molecule structure was found, and the enigma of life was deciphered as a set of information codes of biochemical data; thenceforth the human being has been represented as an input and output information system and, it has been set a discourse that place the cyborg as an image that emphasize the opposition between technology and the living organism. This thesis will develop the idea that virtualization of the human body —it means that the materiality of body becomes virtual when its biological and organic condition is taken to the universe of information codes— consequently it is treating as a living computer system. The phenomenon of body hacking will be explored as a post and transhuman movement, to wonder about the processes of daily interaction between human beings and computer entities.
Editing Digests for Social Networks
Authors: Poselenova Evgeniya , Shapolova Darya
Published: June 2024

Modern people want to keep the track of as many events as possible while saving as much time as possible and reducing the level of redundant information. Internet digests provide an opportunity to systematize online publications and structure relevant information while focusing on the main facts and ideas. The paper describes the algorithm, editing, and design of Internet digests in social media. The authors analyzed digest entries in the Russian VKontakte social network to identify the methods of collecting, processing, and structuring information at different stages of editing. The standard folding method proved to be especially efficient, considering the stylistic diversity of the source materials compiled. As a result, the editor has to standardize the style without violating the integrity of the original text, eliminating information noise, applying the principles of information literacy and multidimensionality, etc. These aspects determine the structure of the VKontate digest as title – lead – text – call to action – graphic elements. The authors developed procedures for digest editorial as a sequence of actions that provides a high-quality media product with a high coefficient of information efficiency. Editing improves the quality of the material while ensuring its relevance, reliability, and clarity, thus facilitating the reading comprehension.
Communicative Patterns of University Students in Virtual Academic Netiquette
Authors: Greenwald Oksana , Islamov Roman
Published: June 2024

Digital communication has become an integral part of social reality to a degree that it prevails in some social contexts, e.g., in academic communication between university students and professors. This research featured violations of netiquette rules by university students and their effect on the effectiveness of virtual academic communication. The article introduces a comprehensive review of domestic and foreign publications on virtual communication and digital etiquette. A survey that involved teaching staff affiliated with higher educational institutions in Kemerovo made it possible to formulate the rules of virtual academic netiquette between university students and professors. The authors identified, quantified, and classified violations of these rules, as well as described the response and attitude of professors to such violations. Although all respondents experienced violations of virtual communication, they believe that local students possess a rather high level of communicative culture. In most cases, poor netiquette did not affect the attitude of teachers towards the violators and caused no strong negative reactions. However, some professors admitted that poor netiquette sometimes caused biased attitude and discomfort on their side in dealing with particular students. Gender, age, or job had no effect on the attitude of professors to students who break the rules of virtual academic etiquette. In general, poor academic netiquette had some negative impact on the effectiveness of communication between professors and university students.
Idioms with Appearance Defect Semantics in Online Beauty Discourse
Authors: Nepomnyaschih Ekaterina
Published: June 2024

The author studied idioms with the meaning of appearance defects in digital beauty discourse using hashtagging is a new phraseologizing tool. New idioms with this semantics reflect the transformation of the linguistic worldview as they objectify the modern value attitudes. The high frequency of these idioms indicates that the semantic code of appearance is of great importance: the induced cultivation of appearance defects motivates users to achieve an ideal beauty image. The analysis revealed the transformation of the linguistic worldview through phraseological innovations that reflect the current value orientations. The paper also defines such terms as neophraseologisms, neophrasemes, phraseological neologisms, and phraseotransforms. The phraseological system follows the general trend of the rapid linguistic development caused by online discourse. Mass linguistic creativity, on the one hand, and global precedence, on the other, trigger many current processes in Russian society.
ECONOMIA SOLIDÁRIA E A AUTONOMIA FEMININA
Authors: Araujo Alcione Lino de , Fahd Plínio Gonçalves
Published: June 2024

The present study aims to investigate the role of the solidarity economy for female autonomy in the Association of Colonies. With this approach, women have been gaining their space in the Association, through the Community Kitchen Project, where they manufacture processed and bakery products; this achievement will also occur in financial independence; where they no longer depend exclusively on their husband. It is essential that the solidarity economy is related to rural development and family farming so that together they can, in a certain way, work for the common good of all. The Association of Colonies supplies fresh and processed products to the Municipal Department of Education in the city of Castro – PR, meeting the requirements of the Federal Government's Public Policy programs, the Food Acquisition Program (PAA) and the National School Meal Program (PNAE). The methodology used in this work is applied, from the point of view of its nature; qualitative and quantitative, regarding the problem; exploratory and descriptive, regarding objectives; survey, regarding technical procedures. As a result, it was verified that in the Association of Colonies, women gained their autonomy through the work they carry out, the manufacture of processed and bakery products. As a result, it was verified that in the Association of Colonies, women gained their autonomy through the work they carry out, the manufacture of processed bakery products. By way of conclusion, one of the main points of the Federal Government's public policy programs – PAA and PNAE – for the Association of Colonies in the city of Castro – PR was the integration between the community, family farming and the various government and social segments.
Immunotherapy in HIV-associated Kaposi Sarcoma: Challenges and
Prospects
Authors: Tawana Tiiso , du Plessis Julianne , Omar Aadilah
Published: June 2024

Kaposi Sarcoma [KS] stems from malignant endothelial cells targeting the cutaneous and
lymphatic systems. The aetiological agent, human herpesvirus type 8, has been implicated in the induction
of KS. Of the four variants of KS that exist, HIV/AIDS associated KS remains one of the
leading cancers in people living with HIV in sub-Saharan Africa [SSA]. It is estimated that approximately
80% of KS cases were attributed to HIV in 2020. Although the introduction of anti-retroviral
therapy [ART] alleviated the burden in 1981, its prevalence on the continent remains significant in
comparison to the rest of the world. Traditional therapeutics such as chemotherapy continue to be the
most common form of managing HIV-associated KS; however, the incidence of this global cancer
continues to rise, predominantly in SSA. Furthermore, a significant number of HIV/AIDS-associated
KS patients had been observed with normal CD4+ count and low viral load levels. This necessitates
the development of other therapeutic strategies to collectively manage the continental crisis. Various
strategies, such as immunomodulatory agents, monoclonal antibodies and therapeutic cytokines, are
being investigated to be used as potential therapeutic strategies. One strategy highlights targeting the
signalling pathways and growth factors involved in angiogenesis, which is an important characteristic
of KS. The PD-1/PD-L1 immune checkpoint blockades are particularly interesting since cell cycle
inhibitors have shown promising results as a potential immunotherapeutic agent. Predictive biomarkers
and alternative vaccines will be discussed here while potential barriers which reduce the
impact of immunotherapy are discussed throughout the review.
Identification of Novel Inhibitors for ERα Target of Breast Cancer By In Silico Approach
Authors: Alagarsamy Veerachamy , Sulthana Mohaideen Thasthagir , Narendhar Bandi , Solomon Viswas Raja , Gobinath Manavalan , Satishchandra Aithamraju , Sangeetha Dubudam , Murugesan Sankaraanarayanan
Published: June 2024

Background:

Estrogen alpha has been recognized as a perilous factor in breast cancer
cell proliferation and has been proficiently treated in breast cancer chemotherapy with the development
of selective estrogen receptor modulators (SERMs).

Objectives:

The major aim of this study was to identify the potential inhibitors against the most
influential target ERα receptor by in silico studies of 115 phytochemicals from 17 medicinal
plants using in silico molecular docking studies.

Methods:

The molecular docking investigation was carried out by a genetic algorithm using the
Auto Dock Vina program, and the validation of docking was also performed using molecular
dynamic (MD) simulation by the Desmond tool of Schrödinger molecular modeling. The ADME(
T) studies were performed by SWISS ADME and ProTox-II.

Results:

The top ten highest binding energy phytochemicals identified were amyrin acetate (-
10.7 kcal/mol), uscharine (-10.5 kcal/mol), voruscharin (-10.0 kcal/mol), cyclitols (-10.0
kcal/mol), taraxeryl acetate (-9.9 kcal/mol), amyrin (-9.9 kcal/mol), barringtogenol C (-9.9
kcal/mol), calactin (-9.9 kcal/mol), 3-beta taraxerol (-9.8 kcal/mol), and calotoxin (-9.8
kcal/mol). A molecular docking study revealed that these phytochemical constituents showed
higher binding affinity compared to the reference standard tamoxifen (-6.6 kcal/mol) towards
the target protein ERα. The results of MD studies showed that all four tested compounds possess
comparatively stable ligand-protein complexes with ERα target as compared to the tamoxifen-
ERα complex.

Conclusion:

Among the ten compounds, phytochemical amyrin acetate (triterpenoids) formed a
more stable complex as well as exhibited greater binding affinity than standard tamoxifen.
ADMET studies for the top ten phytochemicals showed a good safety profile. Additionally, these
compounds are being reported for the first time in this study as possible inhibitors of ERα for
the treatment of breast cancer by adopting the concept of drug repurposing. Hence, these phytochemicals
can be further studied and can be used as a parent core molecule to develop novel
lead molecules for breast cancer therapy.
Book Review: Transnational patriotism in the Mediterranean, 1800–1850
Authors: Leerssen Joep
Published: June 2024

This book has rightly won widespread praise. It traces the multi-sited regional emergence of nationalisms and thus avoids from the outset the internalism that so many histories of national movements fall into: explaining the emergence of nationalism from with the bosom of the pre-existing national community as it responded to its circumstances and challenges.
Variación en la morfología de crías de iguanas negras Ctenosaura pectinata (Wiegmann, 1834) (Squamata: Iguanidae)
Authors: Castro Franco Rubén , Bustos Zagal María Guadalupe , Castro -Bustos Denis , Trujillo-Jiménez Patricia , Mena-Maldonado Félix Emmanuel
Published: June 2024

Con el propósito de contribuir al manejo de Ctenosaura pectinata en condiciones de confinamiento, este estudio presenta análisis estadísticos de nueve variables morfológicas que fueron obtenidas de 127 crías, producidas bajo condiciones de criadero. Las variables examinadas y procesadas con análisis de varianza de una vía, análisis de varianza multivariada, análisis discriminante y análisis de covarianza revelan que la longitud-hocico cloaca (machos= 52.53 mm, hembras= 49.23 mm), la longitud de la cola (macho= 13.59 mm, hembras= 12.30 mm), la longitud de las patas delanteras (machos= 25.99 mm, hembras= 23.08 mm) y las patas traseras (machos= 44.43 mm, hembras= 38.08 mm) de las crías, son los caracteres más grandes en machos que en hembras, como ocurre en los adultos. La diferenciación morfológica del sexo de C. similis en estadio temprano de desarrollo es útil cuando se trabaja en condiciones de granja. Para facilitar el reconocimiento del sexo de las crías se incluye una clave dicotómica con los caracteres más dimórficos.
The Effect of Rake Angle and Cutting Edge Radius on the Orthogonal Cutting Process of Ti6Al4V Alloy
Authors: Mustafa Mohammed , Pervaiz Salman , Deiab Ibrahim
Published: June 2024

This paper investigates the effect of rake angle, α, cutting edge radius, r, and feed rate, f, on the cutting force and cutting zone temperature during orthogonal dry cutting of Ti6Al4V. A numerical model representative of the 2D orthogonal cutting process is developed using ABAQUS/Explicit software. Johnson-Cook, (JC) constitutive material model is used to describe material plasticity. JC damage model and energy-based fracture criterion are used to describe damage initiation and evolution. Using Minitab-19 software, Taguchi L9 orthogonal array (3 × 3) is implemented to plan simulation trails. Assuming a constant cutting speed of 500 mm/min, three levels for each factor are considered α (-5°, 0°, 5°), r (0.02, 0.04, 0.06 mm) and f (0.1, 0.2, 0.3 mm). The cutting force and cutting zone temperature are analyzed using ANOVA. Based on a 90% Confidence Interval (90% CI), the results show that only feed rate significantly affects the cutting force. However, rake angle, cutting edge radius, and feed rate do not substantially affect cutting zone temperature.
Persuasive Systems Design Trends in Coronary Heart Disease Management: Scoping Review of Randomized Controlled Trials
Authors: Agyei Eunice Eno Yaa Frimponmaa , Ekpezu Akon , Oinas-Kukkonen Harri
Published: June 2024

Background

Behavior change support systems (BCSSs) have the potential to help people maintain healthy lifestyles and aid in the self-management of coronary heart disease (CHD). The Persuasive Systems Design (PSD) model is a framework for designing and evaluating systems designed to support lifestyle modifications and health behavior change using information and communication technology. However, evidence for the underlying design principles behind BCSSs for CHD has not been extensively reported in the literature.

Objective

This scoping review aims to identify existing health BCSSs for CHD, report the characteristics of these systems, and describe the persuasion context and persuasive design principles of these systems based on the PSD framework.

Methods

Using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) guidelines, 3 digital databases (Scopus, Web of Science, and MEDLINE) were searched between 2010 to 2022. The major inclusion criteria for studies were in accordance with the PICO (Population, Intervention, Comparison, and Outcome) approach.

Results

Searches conducted in the databases identified 1195 papers, among which 30 were identified as eligible for the review. The most interesting characteristics of the BCSSs were the predominant use of primary task support principles, followed by dialogue support and credibility support and the sparing use of social support principles. Theories of behavior change such as the Social Cognitive Theory and Self-Efficacy Theory were used often to underpin these systems. However, significant trends in the use of persuasive system features on par with behavior change theories could not be established from the reviewed studies. This points to the fact that there is still no theoretical consensus on how best to design interventions to promote behavior change in patients with CHD.

Conclusions

Our results highlight key software features for designing BCSSs for the prevention and management of CHD. We encourage designers of behavior change interventions to evaluate the techniques that contributed to the success of the intervention. Future research should focus on evaluating the effectiveness of the interventions, persuasive design principles, and behavior change theories using research methodologies such as meta-analysis.
Use of Conversational AI Chatbots for Retinitis Pigmentosa Patients: a Semantic Textual Analysis (Preprint)
Authors: Del Buono Milan , Wu Gloria , Wong Adrial
Published: June 2024

BACKGROUND

Retinitis Pigmentosa (RP) is a genetic disease that causes progression vision loss, which almost invariably leads to blindness. Being a rare disease, RP is costly to diagnose and takes a long time to diagnose. Patients may inevitably turn to ChatGPT or similar large language AI models (LLMs) to answer some of their questions, however, given the amount of incorrect information on the internet combined with small training data available for RP, the answers may not be correct.

OBJECTIVE

We sought to investigate how correct 4 LLMs’ (ChatGPT 3.5 and 4.0, Claude, and Copilot) answers were for RP by comparing them semantically via cosine score to the American Academy of Opthalmology’s (AAO) webpage on RP.

METHODS

Embeddings for the LLM's outputs were computed using the MiniLM-v2 model from HuggingFace and the cosine between the AAO's sentence and the LLM's sentence were taken. To summarize the data, New Dale-Chall readability scores were calculated.

RESULTS

We find that the LLMs answer the questions reasonably similarly to the AAO, and there was no significant difference between ChatGPT 3.5, 4.0, and Claude; Copilot had lower cosine scores. However, every LLM had a significantly harder readability level, indicating that LLM outputs may be difficult for the lay public to comprehend.

CONCLUSIONS

This study demonstrates that AI models can produce conversational text that is highly accurate. Their high semantic similarity to the AAO's official website indicates that they provide good background information to curious patients. LLM's future use in patient education cannot be ignored, as AI technology is further adopted.
Effects of Digital Interventions on Neuroplasticity and Brain Function of Individuals With Developmental Disabilities: A Systematic Review (Preprint)
Authors: Lee Hyunyoung , Shin Yoomi , Choi Yuna , Moon Hayoung , Lee Anna
Published: June 2024

BACKGROUND

Developmental disabilities (DDs) impact individuals’ cognitive, psychological, and motor functions, and those with DDs show specific neural differences. Research suggests the importance of interventions to enhance neuroplasticity, which is the brain’s ability to adapt to stimuli, as well as effectiveness of digital interventions for this population. However, there is a lack of comprehensive review on intervention outcomes from relevant existing studies.

OBJECTIVE

This systematic review aimed to investigate the effects of digital interventions on neuroplasticity and neural functions of individuals with DDs.

METHODS

Based on the Joanna Briggs Institute guidelines, a systematic review was conducted on PubMed, PsycINFO, CINAHL, and Scopus databases. Studies that focused on digital interventions to enhance neuroplasticity of individuals with DDs and used neuroimaging methods to evaluate the effectiveness were included. The results of the current review were synthesized based on Roy’s adaptation model.

RESULTS

Of the 2824 retrieved studies, 30 were included in this review. The included studies used cognitive training, neurofeedback, and social cognitive training integrated with digital devices, mostly virtual reality. Neuroimaging results after digital interventions demonstrated changes in brain wave patterns and increased activation in certain regions. Behavioral assessments exhibited significant improvements including attention- deficit/hyperactivity disorder symptoms, attention, emotional recognition, and social skills than before the intervention.

CONCLUSIONS

Digital interventions are promising in enhancing neural functions and neuroplasticity in individuals with DDs. Further studies with diverse methodologies and a broader spectrum of DDs are essential to fully understand the potential of digital interventions in neurodevelopmental challenges among the population.
Proceedings from a multidisciplinary workshop defining the scope of Resilience Informatics in Public Health (Preprint)
Authors: Block Ngaybe Maiya G. , Azurdia Sierra Lidia , McNair Andrew , Gonzalez Myla , Iyengar M Sriram
Published: June 2024

BACKGROUND

In recent years, public health has confronted two formidable challenges: the devastating COVID-19 pandemic and the enduring threat of climate change. The convergence of these crises underscores the urgent need for resilient solutions. Resilience Informatics (RI), an emerging discipline at the intersection of informatics and public health, offers promising avenues for mitigating and adapting to these challenges. Addressing critical questions regarding target audiences, privacy concerns, and scalability is paramount to fostering resilience in the face of evolving health threats.

OBJECTIVE

The University of Arizona's workshop on Resilience Informatics in Public Health was held in November 2023 to serve as a pivotal forum for advancing these discussions and catalyzing collaborative efforts within the field.

METHODS

A purposive sampling strategy was employed to invite 40 experts by email from diverse fields including public health, medicine, weather, informatics, environmental science, and resilience to participate in the workshop. The event featured presentations from key experts followed by group discussions facilitated by experts to ensure diversity in backgrounds. Attendees engaged in collaborative reflection and discussion on predetermined questions. Discussions were systematically recorded by University of Arizona students, and qualitative analysis was conducted. A rapid analysis of workshop notes was initially performed, followed by a more comprehensive qualitative thematic analysis. A codebook was developed iteratively, all transcripts and notes used from the workshop were coded twice using MAXQDA software. Discrepancies in coding were resolved through discussion, leading to a narrative synthesis of findings.

RESULTS

The workshop hosted 27 attendees at the University of Arizona, predominantly from academia, with 21 participants from public health-related fields and 8 experts in resilience. Additionally, participants from governmental agencies, Native American groups, weather services, and mHealth organizations attended. Qualitative analysis identified major themes, including the potential of resilience informatics (RI) tools, threats to resilience (e.g., healthcare access, infrastructure, climate change), challenges with RI tools (e.g., usability, funding, real-time response), and standards for RI tools (e.g., technological, logistical, sociological). Attendees emphasized the importance of equitable access, community engagement, and iterative development in RI projects.

CONCLUSIONS

The RI workshop emphasized the necessity for accessible, user-friendly tools bridging technical knowledge and community needs. Future directions include focused discussions to yield concrete outputs like implementation guidelines and tool designs, prioritizing community engagement, cultural sensitivity, and ongoing learning.

CLINICALTRIAL

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