bluuebunny/crossref_metadata_2025 huggingface dataset:
Migránsok gyermekeinek szocializációja
Authors: Dajnoki Krisztina , Balázs-Földi Emese , Móré Marianna
Published: December 2021

A migráns gyerekek befogadásával kapcsolatos feladatok jelenős kihívások elé állítják a pedagógusokat. Tanulmányunk fókuszában az a kutatási kérdés áll, milyen tényezők játszanak szerepet a migráns gyerekek sikeres beillesztési folyamatában? Célunk ismertetni az integrációs kihívásokat, a kapcsolódó statisztikai adatokat és átfogó képet adni a tanulók iskolai beilleszkedését segítő tényezőkről. Megállapítható, hogy a sokszínűség elősegíti a szinergiát a közösségben, pozitívan hat az eredményességre, ugyanakkor az iskola a társadalmi problémák megoldásában kevésbé hatékony. Az iskola működéséhez igazított problémakezelés a pedagógiai gyakorlat átrendezéséhez, hosszabb távon pedig a társadalmi eredményességhez is hozzájárulhat. A pedagógiai folyamat kiegészítéseként tekintünk az iskolai szociális munka új típusú szolgáltatás rendszerére. Véleményünk szerint képzés tartalmi elemeit érdemes lenne kiterjeszteni a migráns gyerekek befogadását segítő módszerek ismertetésére.
Erişkin bir hastada pulmoner sekestrasyon
Authors: PINARCI Cihat , BAYRAKTAROĞLU Selen , CAN Özge
Published: December 2021

Pulmoner sekestrasyon, nadiren erişkinlerde gözlenen konjenital bir akciğer malformasyonudur. Genellikle erken çocukluk çağında tanı konulur. İntra ve ekstralobar olmak üzere iki tipi vardır. Tanıda en önemli bulgu, sistemik arteryal sistemden köken alan arteri ve pulmoner veya sistemik venlere drene olan bir venöz yapısı olmasıdır. BT bulguları erişkin yaş grubunda pnömoni ya da kitle ile karışabilmektedir. Tanı için tipik lokalizasyon ve besleyici vasküler yapının BT anjiyografik demonstrasyonu önemlidir.
Training of interpreters for International Army Games
Authors: Shevchenko Mikhail A. , Ryumin Boris A. , Tavdgiridze Levan A. , Belov Danil N.
Published: December 2021

This study considers the process of training of language support specialists for International Army Games (IAG) as well as its problems. General information on IAG (history, fields, geography, organisational structure, etc.) is given with its correlation to the language support tasks. In connection with the annually increasing interest in this type of competition (17 participating countries in 2015 and 32 in 2020) and, accordingly, increasing needs for interpreters, justifies the relevance of this study. Specific IAG situations where translation is being carried out are given. The scientific novelty of the study lies in the low degree of coverage of the topic and the lack of a centralized algorithm for the preparation of interpreters for this international event. Considering the nature of the linguistic tasks performed during the preparation and conduct of the IAG, the basic requirements to the specialists being sent are formed. The experience of participation as an interpreter at the IAG is presented and analyzed, the problematic issues in terms of linguistic training and background knowledge are pointed out. A comparison of the two methods of training interpreters involved in the IAG, the main advantages and disadvantages of each of the two methods is given. As a result of the above-mentioned analysis a list of recommendations on the preparation of specialists in linguistic support for IAG is formed, taking into account the specific situations in which the translation is carried out. A conclusion about the further development of this direction and the ways of solving the indicated problems is made.
The role of corpus analysis in the study of English loanwords and in teaching a second foreign language (on the example of French and Italian)
Authors: Zimina Elena I. , Gubanov Dmitrii A.
Published: December 2021

We argue that corpus linguistics should be used as a tool for teaching students a second foreign language. The researchers focus on the study of English loanwords in French and Italian. We propose a new approach to teaching a second foreign language to students who are fluent in English as a first foreign language. We emphasize the importance of concordance in linguistics and teaching a second foreign language. We analyze the works of the methodologists who suggest using corpus technologies in the language classroom to develop students’ lexical skills. We touch upon the characteristics of corpus technologies, define the term “loanwords” and refer to the concept of “English borrowings”. The researchers analyze the role of English loanwords in French and Italian, and identify the spheres where English borrowings are mainly used. Based on the language of the media, we study the models of assimilation of English loanwords in French and Italian. We focus on the most popular English loanwords used in France and Italy, provide statistical data on their use and analyze their grammatical and semantic assimilation. We analyze the most popular loanwords from the English language; study their origin, language context and the way they were modified according to the patterns of the receiving languages. It is advisable to implement the proposed approach in teaching the vocabulary of a second foreign language and to use other tools of corpus linguistics as teaching methods.
Development of a probable psychological profile for social network user
Authors: Komarov Vladimir V.
Published: December 2021

We present an overview of the current state of the issue of developing a psychological profile of a social network user, including methodological and applied aspects. The deviant behavior issue among students on the Internet and its prevention in the educational environment is relevant. The author's psychological technology to build a probable psychological profile of a social network user is presented. According to the method of analyzing the content of the user's Internet page, the method of profiling corresponds to the method of analyzing documents, which is used, in particular, in the complex forensic psychological and linguistic examination of documents with extremist content. It is recommended to take into account the main theme and title of the text; the concepts used in the text; the modality of the emotional evaluation of the object to which the narrative is dedicated; the formation of a certain attitude of the audience towards this object. The development and construction of a probable psychological profile of a social network user are based on systemic, activity-based, subjective approaches, the main provisions of general, social, pedagogical, age and legal psychology, imagology, the basics of forensic psychological examination and methods: analysis of documents with elements of content analysis, psychological reconstruction and drawing up a psychological profile. Using this technology to prevent social deviations, criminal behavior, to develop methodological recommendations for teachers and psychologists on psychological and pedagogical support for children and adolescents with identified social deviations is possible.
Pedagogical diagnostics of professional identity formation among cadets using expert assessment method
Authors: Meshcheryakova Elena I. , Panferkina Irena S. , Paschinskaya Lyudmila I.
Published: December 2021

We consider the current issue of pedagogical diagnostics of professional identity formation among cadets with expert assessment method for its implementation. The expert assessment method is one of the system elements of pedagogical diagnostics methods, we present the features, advantages and disadvantages of its use for assessing the professional identity formation among cadets, directions are proposed to increase the effectiveness of the expert assessment method and overcome its shortcomings in the process of diagnosing the formation of professional identity of cadets. The main requirements for experts – subjects of pedagogical diagnostics are to use methods within the framework of objective (documentary, experimental) and subjective (self-assessment of competence, mutual assessment by experts of other potential experts) approaches for the selection of experts. In addition to theoretical, the study has practical significance, which consists in the fact that its results can contribute to the effective use of the method of expert assessments not only to study the dynamics of the formation of professional identity of cadets in the educational process of military universities, but also to identify signs of such a dangerous psychological phenomenon as professional marginalization – the antipode of professional identity.
Social and pedagogical partnership of kindergarten and family as a condition for positive socialization of young children
Authors: Karpova Svetlana I. , Savenkova Tatiana D.
Published: December 2021

The urgency of the issue of positive socialization of young children is due to the growing scientific interest in the processes of sociogenesis in early and preschool childhood, the child’s mastery of social experience in a constantly changing socio-cultural situation. The family as the first agent of the child’s socialization experienced the negative influence of factors of the modern socio-cultural environment; itself needs pedagogical assistance and support to perform the function of social education of the child, the formation of age-appropriate social behavior skills. The purpose of the study: based on an analytical review of scientific sources, to identify the primary mechanisms of socialization of a child at an early age, to develop a model of pedagogical support for positive socialization of young children in the conditions of social and pedagogical partnership of kindergarten and family, to test its effectiveness during a pedagogical experiment. The approbation of the model of pedagogical support for positive socialization of young children in the conditions of socio-pedagogical partnership of kindergarten and family with the inclusion of parents in the educational process contributes to the successful passage of children through all stages of social adaptation, including reducing the timing of each stage, and the formation of expected forms of social behavior in children during the adaptation period. The material of the research can be useful for further applied research in the field of pedagogical support for the formation of age-appropriate mechanisms of positive socialization in children in early childhood in the conditions of public education and education.
Features of educational and professional activities of future social workers in legal competence formation
Authors: Khodaev Aleksey S.
Published: December 2021

We consider the features of the educational and professional activities of future social workers in the legal competence formation. The components of legal competence are analyzed: motivational-value, cognitive, communicative and activity-reflexive. The formation of these components takes place through the involvement of future social workers at all levels of professional education in social and legal activities by creating pedagogical conditions: the formation of a value attitude to the legal aspects of professional activity among future social workers; purposeful and active self-knowledge of the student, mastering the legal aspects of professional activity by solving different levels of complexity of educational and professional tasks; acquaintance of future social workers with the professional community through internships in institutions, the implementation of volunteer activities on the basis of various organizations, participation in scientific conferences, seminars, round tables, etc.; orientation of students to active legal education and reflection. Considering the stages of student personal development (stage of holistic personal development, stage of specialized personal development, stage of strengthening professional preparedness) in the university continuing legal education of future social workers is necessary. All types of activities at each of the stages of personal development of the introduction of legal education and upbringing are necessary.
origines des oppositions idéologiques dans la zone sahélienne
Authors: Paré Moussa
Published: December 2021

L’article « Aux origines des oppositions idéologiques dans la zone sahélienne. Les Almoravides dans le Bilad al-Sudan occidental au XIe siècle » analyse les raisons politiques et idéologiques de l’expansion almoravide dans le Bilad al-Sudan. Il ressort ainsi de l’analyse des sources narratives arabo-musulmanes que la volonté des émirs almoravides d’éradiquer les hérésies kharidjites d’une part, et d’autre part la fondation d’un vaste empire malékite dans le Dar al-Islam occidental ont motivé la poussée almoravide vers le Soudan Occidental. Ces desseins d’ordre idéologique et politique ont favorisé la diffusion d’un islam orthodoxe. Jusque-là le Bilad al-Sudan était traversé par des clivages ethniques, sociaux et religieux. L’islam s’y trouvait mêlé de tendances hétérodoxes : chiisme et surtout le kharidjisme. Le mouvement almoravide a réalisé cette union sous la bannière du malékisme triomphant.
The Latin American Integration Route and local development in light of the constitutions of Brazil, Paraguay, Argentine and Chile
Authors: Oshiro Reynaldo Gabriela , Joichi Sunakozawa Lucio Flavio , Cantero Dorsa Arlinda
Published: December 2021

Based on the social, legal and economic implications imposed by globalization, as well as the integration between nations, this paper proposes to discuss the concept of development by analyzing the constitutions of Brazil, Paraguay, Argentine, and Chile, considering that a debate between academia and other institutions emerges in the Latin America integration context. This is an urgent and necessary dialogue to guide possible courses for this region. Countries from the most diverse continents already indicate a break in customs tariffs and the rise of new economic agreements, bringing countries of the Latin-American Integration Route (RILA) closer to the countries of today's greatest and most solid economic bloc, the European Union. This sets a precedent for the idea that RILA is becoming a macro-territory of increasing economic, social and legal visibility, which is a reason why thinking about regional development is a priority task, as well as drawing up studies and reflections that lead to a possible harmonization and integration of legal norms. These are tasks of the governments, academia, companies, and civil society. Furthermore, the present work discusses the need for legal grounds involving countries that make up the RILA, in order to provide greater legal security and dignity for the subjects involved in this intense process.
Formación de capital humano con vistas al desarrollo de ciudades impactadas por el Corredor Vial Bioceánico
Authors: De Oliveira Edilene Maria , Cantero Dorsa Arlinda , Matos de Farias Bruno , Miranda Maria Geralda
Published: December 2021

El Corredor Vial Bioceánico unirá los océanos Pacífico y Atlántico, pasando por Brasil, Paraguay, Argentina hasta llegar a los puertos de Chile. Esta iniciativa traerá importantes cambios económicos, sociales y ambientales al Estado de Mato Grosso do Sul. Si este corredor es una ruta para la integración de América Latina y una política estratégica, los países involucrados son enfáticos en reconocer que, en el suelo, será un corredor para el paso de mercancías, sino una que traerá desarrollo a todas las regiones que se encuentran rastro de esta ruta. Las ciudades del Estado de Mato Grosso do Sul donde habrá acceso al corredor, a excepción de la Capital Campo Grande, son pequeñas ciudades que pueden impactarse directamente en diversos sectores, como infraestructura, turismo, ocio. y hostelería y gestión empresarial. Habrá necesidades para atender los requerimientos laborales que se vayan planteando, requiriendo formación y cualificación profesional para atender las nuevas demandas laborales. Así, este estudio tiene como objetivo aportar una visión del desarrollo en sus diversas concepciones, así como señalar posibilidades de cualificación profesional en numerosas áreas que deberán ser priorizadas en el corto, medio y largo plazo, para que el Estado de Mato Grosso do Sul logre desarrollar su mano de obra local. A partir de una investigación bibliográfica y documental, se concluyó que la oferta de cursos técnicos y de educación inicial y continuada para jóvenes y personas en general, puede servir positivamente a los municipios de Mato Grosso do Sul por donde pasa la Ruta de la Carretera Bioceánica, formando y capacitando su capital humano, con vistas al desarrollo de las localidades.
La Ruta de la Integración Latinoamericana (RILA), su influencia cultural y desafíos turísticos
Authors: Ferreira Magali Luzio , Castilho Maria Augusta , Leonel Waldir
Published: December 2021

Esta investigación tiene como objetivo sacar a la luz la reflexión histórica sobre la creación e importancia de las formas interaccionistas a lo largo del proceso histórico del mundo, desde las primeras civilizaciones hasta la contemporaneidad. Para realizar el estudio reflexivo y comprender la necesidad de esta unión territorial, se utilizó el método deductivo con cobertura sistémica, a través de bibliotecas, libros, periódicos, sitios web, señalando los trabajos que daban soporte al trabajo en pantalla. El estudio incluye autores que trabajan sobre el contexto histórico como: Pinsky (2005) y Fausto (2013); concepto de espacio enfatizado por Raffestin (2013); lo diferente y lo nuevo, destacado por Canclini (2003) y también hay aspectos del turismo que presenta Barreto (2016). Sedentario, con la necesidad política de una demarcación fronteriza como las grandes murallas que dividen enemistades, ya sea por razones ideológicas o económicas. Sin embargo, las innovaciones del estrechamiento territorial que actualmente dependen de las rutas turísticas, que buscan no solo la facilitación económica, sino también el entretenimiento vinculado a las interacciones culturales. La “Ruta de la Integración Latinoamericana” (RILA) El proyecto crea relaciones de medidas económicas necesarias y visibilidad cultural que promueve la expansión del mercado turístico, con propuestas innovadoras para el turismo local y se puede transformar en un corredor para el flujo de la producción agrícola de Brasil, Paraguay, Chile y Argentina y privilegiar la cultura local a través de diversos segmentos de ocio.
INCREASING MICROGRID ENERGY EFFICIENCY WITH DIESEL GENERATORS
Authors: Denysiuk S. , Boiko I.
Published: December 2021

It is shown that increasing the energy efficiency of Microgrid with diesel generators requires solving the problem of optimizing the modes of operation of Microgrid using as an optimization criterion for reducing the consumption of primary fuel diesel generators. To study the energy efficiency of such types of Microgrid as a criterion that has a direct impact on the amount of electricity generated, selected adequate accounting of primary fuel consumption when generating a given amount of electricity in the system.

The article determines that one of the important indicators of diesel generator sets is their efficiency, which is determined by the ratio of energy produced to fuel consumption per hour of operation at rated load. It is shown that the reduction of fuel consumption allows to increase the efficiency of diesel generators, and different types of steady and transient modes of diesel generators significantly affect the efficiency of Microgrid in terms of technical and financial efficiency.

To improve the technical and economic indicators in Microgrid with diesel generators, the article proposes to use the electric cost model of the power generation system, which allows to calculate both the dynamic change of generated power and the dynamic change of its cost and the cost of primary fuel. This model allows flexible nonlinear tracking of fuel consumption, which, taking into account the cost of diesel fuel, can serve as an economic criterion for determining the energy efficiency of the generating system.

The article presents an algorithm for evaluating the financial and technical performance of Microgrid in dynamic modes over a period of technology, which not only evaluates the economic and energy efficiency of Microgrid with diesel generators, but can also be used to modify Smart meters, which can significantly expand their functionality.
Axisymmetric vibrations of a cylindrical final height piezoceramic shell
Authors: Korzhik Oleksii Volodymyrovych , Petrishchev Oleh Mykolaiovych , Filippova N.Yu.
Published: December 2021

A new approach to describing the formation of an electric field in a material is proposed electroelastic transducer, which presented in the form of a cylindrical circular thin-walled radial polarized shell. The problem was solved by the "end-to-end" method, which involves a joint solution equations for acoustic, mechanical and electric fields taking into account physical properties of the emitting transducer. The general analytical solution "end-to-end" problem in the form of a system of resulting equations for the considered electroelastic oscillatory system in vacuum with distributed parameters written with respect to axial and radial displacement
Fourier transform and transients
Authors: Mironov N.A. , Pilinskij V.V.
Published: December 2021

The opportunity of expansion of a scope of a method of Fourier transformation for analysisof transients in electric circuits and systems due to elimination of traditionally put forwardrestrictions on application of this method is considered
MEDIA FAKES IN THE INFORMATION SPACE OF THE CORONAVIRUS PANDEMIC
Authors:   Herzen State Pedagogical University of Russia, Gurochkina A.G. , Makurova D.A. ,   Herzen State Pedagogical University of Russia
Published: December 2021

The paper explores the grave issue for modern-day research of mass media communication - fake news. The study aims at identifying cognitive bases and mechanisms of formation of media fakes about coronavirus. The first part of the article defines fake news and delineates salient characteristics of fake news. The second part of the article reveals some common semantic macrostructures of media fakes about the virus based on the analysis of social media posts and news articles. The third part of the article presents and describes the key strategies and tactics of manipulation and information distortion typical of fake news about the virus. The analysis reveals essential cognitive and pragmalinguistic components of coronavirus media fakes. The results of the undertaken research are relevant to further exploring other features of fake news and can be implemented as a guide for identifying fake news in order to reduce the mass addressee’s susceptibility to fakes.
PUNCTUATION AS A MEANS OF ORGANISING ENGLISH FICTION DISCOURSE
Authors:   Lomonosov Moscow State University, Sapunova O.V.
Published: December 2021

The article considers the role of punctuation marks in delivering and perceiving the purport in fiction discourse. The core of the study is the interrelation between the punctuation arrangement of the text and its prosodic embodiment. Contemporary English fiction in both written and audio forms is exploited as the material for the investigation. The key goal of the study is to demonstrate the so-called ‘highlighting function’ of the semicolon (the stop of inner controversy) and to analyse its role in emphasising the text fragments of special prominence. Three major types of the function are discussed: bringing out particularization to follow, which appears to be vital for interpreting the purport; marking off the afterthought; bringing out the ‘effective’ conclusion - a concise and catchy phrase summing up the previous statement. The results show that in all the three contexts in which the semicolon signals the information significance, its typical prosody gets modified. Namely, the part of the sentence after the stop is largely produced in the higher section of the diapason as compared to the recommended parameter. Among other prosodic characteristics to be altered are timbre and tempo. Adding more expressivity not infrequently may enable the performer to highlight the clause to follow.
GRAMMATICAL SCHEMAS OF SECONDARY LINGUISTIC INTERPRETATION
Authors:   Derzhavin Tambov State University, Boldyrev N.N.
Published: December 2021

The author analyses grammatical forms of linguistic cognition which are used for primary and secondary interpretation of the world in the process of its mental construal in language, i.e. cognitive schemas of direct interpretation of variety of objects, events and of their characteristics as they are perceived in the world around (primary interpretation), on the one hand, and those of interpretation of previously gained and verbalized conventional knowledge about the world, on the other. He argues that structuring world and world knowledge in the processes of conceptualization and categorization is always interpretative and follows some general, or conventional, and specific, or individual, cognitive schemas. This argument is derived from the author-suggested three-member pattern of language functions, claiming ‘the interpretive function’ to be a basic one along with the cognitive and communicative functions. It is the interpretive function of language that requires a broad choice of schemas to structure the world and the world knowledge and to trigger basic processes of linguistic interpretation. Among the conventional grammatical schemas employed in these processes are certain types of concepts and categories, propositional, metaphoric, and metonymic models represented by different types of syntactic structures, simple or complex, as well as the structure of various types of texts. Individually specific can be human particular systems of conceptualization and categorization, complex propositions, newly-construed metaphors, and modified conventional schemas which are specifically represented in language.
GEOMETRICAL–TOPOLOGICAL CHARACTERISTICS OF THE SUBSOLIDUS STRUCTURE IN THE MgO – Al2O3 – TiO2 SYSTEM
Authors: Borysenko Oksana , Logvinkov Sergii , Shabanova Halyna , Остапенко Igor , Шумейко Vita
Published: December 2021

Among the materials that attract attention from the point of view of creating refractory products with increased heat resistance, one can single out materials based on compositions of the MgO – Al2O3 – TiO2 system. As a result of the thermodynamic analysis of the MgO – Al2O3 – TiO2 system, it was found that the partition of the system into elementary triangles will change in three temperature ranges: I – up to 1537 K, II – in the temperature range 1537 – 2076 K and above 2076 K. It has been established that up to a temperature of 2076 K there is a concentration range of spinel phases: magnesium aluminate spinel – quandylite. Above 1537 K, there is a concentration range: tialite – karroite, which meets the requirements for materials with high heat resistance. The elementary triangle TiO2 – Al2TiO5 – MgTi2O5 can be used to obtain heat–resistant materials based on Al2TiO5 stabilized by MgTi2O5. To obtain heat–resistant periclase–spinel materials, an elementary triangle Mg2TiO4 – MgAl2O4 – MgO is recommended, in which only compounds with a cubic crystal lattice are present. Thus, the division of the MgO – Al2O3 – TiO2 system into elementary triangles and the analysis of the geometrical–topological characteristics of the phases of the system made it possible to select in the system under study the regions of compositions that have optimal properties for obtaining materials with the specified optimal properties.
FEATURES OF THE STRUCTURE FORMATION OF SPODUMENS-CONTAINING GLASS-CRYSTAL MATERIALS AFTER HEAT TREATMENT
Authors: Savvova Oksana , Voronov Gennady , Rіabinin Svіatoslav , Fesenko Alexey , Svishov Dmitry
Published: December 2021

The promising areas of application of spodumene–containing glass–crystalline materials in various branches of science and technology, in particular, to increase the defense capability of the state, have been determined. The relevance of the development of lightweight high–strength sitalls based on them, taking into account the aspects of energy saving for obtaining armored elements, has been determined. It has been established that the use of IR spectroscopy is promising for studying the nanostructure of glass–crystalline materials. The compositions of lithium aluminum silicate glasses and the modes of their heat treatment have been developed. The features of the structure formation of spodumene–containing glass–crystalline materials obtained under the conditions of two–stage low–temperature heat treatment have been investigated. Taking into account the analysis of the nature of the IR spectra of chain silicates, the structure of glass–crystalline materials was investigated according to the IR spectra and the nature of structure formation was established depending on the initial composition of the glass. It has been established that the formation of a structural glass network with the participation of tetrahedra [AlO4], [BO4] and [SiO4] and the presence of cybotaxic groups [Si2O6] allows, under conditions of two–stage low–temperature treatment, to provide bulk crystallization of spodumene–containing glass–crystalline materials. It has been established that the formation of the vitrified structure of glass–crystalline materials allows to ensure their high values of Vickers hardness, microhardness and crack resistance and by the presence of a glass phase, which plays the role of a damper, to ensure their high armor resistance. This will increase the efficiency and make it possible to use them as an energy–destructive and energy–absorbing layer in the composition of the armor element «metal alloy – ceramics – sitall». The introduction of spodumene–containing glass–crystalline materials will increase the competitiveness of competitive domestic armored elements for personal protection.
ON THE KINETICS OF ANODIC PROCESSES AT OXIDATION OF AQUEOUS SOLUTIONS OF DIMETHYL SULFOXIDE
Authors: Abdulhadi Saif Ali , Tulskа Alona , Bayrachnyi Volodymyr , Sinkevich Irina Valeriivna
Published: December 2021

Dimethyl sulfoxide is a feedstock for a large number of organic substances syntheses. Nowadays research is considerably focused on the production of general products of dimethyl sulfoxide oxidation – dimethyl sulfone and methane sulfonic acid. Dimethyl sulfone is well–known as a food supplement for the treating and strengthening of human joints and ligaments. dimethyl sulfone is basically synthesized by oxidation of dimethyl sulfoxide in hot 30 % hydrogen peroxide in glacial acetic acid. Synthesis is accompanied by significant losses of hydrogen peroxide, the target product has to be significantly purified. It becomes possible to control the synthesis of pure dimethyl sulfone and methane sulfonic acid when using the electrochemical method of oxidation of dimethyl sulfoxide in its aqueous solution with chemically resistant anode and high overvoltage of oxygen reaction Controlled synthesis is relevant because sulfur tends to change the oxidation rate. Study of kinetics of anodic processes at platinum electrode was performed in the dimethyl sulfoxide concentration range about 1.0…4.0 mol∙dm–3. Current raise was observed at potentials that are more positive than 1.3…1.4 V. This potential range corresponds to oxygen release. Dissolved sulfuric acid (0.2 mol∙dm–3) was added in order to inhibit the oxygen release and achieve the potential for the formation of peroxide radicals in aqueous solutions of dimethyl sulfoxide. It is known that sulfate ions are adsorbed on the surface of the platinum anode, displacing molecules of protonated water. This allows to shift the potentials and increase of the electrolysis current in 0.2 mol∙dm–3 H2SO4 to 1.7…1.9 V. It indicates the processes of formation of peroxide radicals on the surface of the platinum anode. Further shift of the anode potential into more positive area than 2.00…2.05 V leads to a rapid increase in current density. At such potentials, dimethyl sulfoxide and dimethyl sulfone are oxidized to methane sulfonic acid with a parallel oxygen and hydrogen peroxide release. Current–voltage study has shown that the oxidation of dimethyl sulfoxide in aqueous solutions runs through the formation of dimethyl sulfone. When conducting electrochemical synthesis with control of the anode potential, it is possible to produce dimethyl sulfone without further oxidation to methane sulfonic acid. The addition of 0.2 mol∙dm–3 H2SO4 to aqueous dimethyl sulfoxide solutions inhibits oxygen release and intensifies oxidation of dipole dimethyl sulfoxide molecules adsorbed on the platinum surface. The influence of adsorption processes on the kinetics of anode processes at the platinum anode in aqueous solutions of dimethyl sulfoxide at high anode potentials has been studied.
Open thoracic surgical implantation of cardiac pacemakers in rodents
Authors: Yin Rose T. , Chen Sheena W. , Lee K. Benjamin , Choi Yeon Sik , Koo Jahyun , Yang Quansan , Napolitano Michael A. , Ausra Jokubas , Holleran Timothy J. , Waters E. Alex , Brikha Anlil , Kowalik Grant , Miniovich Alana N. , Knight Helen S. , Russo Bender A. , Murillo-Berlioz Alejandro , Haney Chad R. , Gutruf Philipp , Rogers John A. , Trachiotis Gregory D. , Efimov Igor R.
Published: December 2021

Genetic engineering and implantable bioelectronics have transformed investigations of cardiovascular physiology and disease. However, the two approaches have been difficult to combine in the same species: genetic engineering is applied primarily in rodents, and implantable devices generally require large animal models. We recently developed several miniature cardiac bioelectronic devices suitable for mice and rats to combine the advantages of molecular tools and implantable devices. Successful implementation of these device-enabled studies requires microsurgery approaches that reliably interface bioelectronics to the beating heart with minimal disruption to native physiology. This protocol describes how to perform an open thoracic surgical technique for epicardial implantation of novel wireless cardiac bioelectronic devices in adult rats and has significantly lower mortality than transvenous implantation approaches. In addition, we provide the methodology for a full biocompatibility assessment of the physiological response to the implanted device. The surgical implantation procedure takes about 40 minutes to complete for an experienced operator, and up to 8 surgeries can be completed in one day. Implanted pacemakers provide programmed electrical stimulation for over 1 month. This protocol has broad applications to enable fully conscious in vivo studies of cardiovascular physiology in transgenic rodent disease models.
Protocol for bloodmeal identification in ticks using retrotransposon-targeted real time PCR
Authors: Goethert Heidi
Published: December 2021

Tick-borne infections are a global public health burden. Our ability to develop effective control measures relies on understanding the natural transmission cycles as well as the mode of exposure to humans. Our current knowledge of the relative importance of the hosts upon which tick vectors feed is based on indirect measurements, such as infestation indices. Bloodmeal identification can determine the host upon which a questing tick had fed in the previous life stage and is an unbiased method for incriminating reservoir hosts. Although bloodmeal identification has been utilized for mosquito ecology since the 1950s, the extended life-cycle of ticks and complete intracellular digestion of the bloodmeal make such analyses for ticks more complicated. We have recently developed a highly sensitive assay for identification of bloodmeals in ticks based upon real-time PCR amplification of mammalian retrotransposons. Although other PCR-based methods for bloodmeal analysis in ticks have been published previously, they have an inadequate success rate with field-collected ticks and have not been adopted for general use. We describe our methods in detail in order to make this assay widely accessible for use in other laboratories.
Association Study of BIF-1 Gene Expression with Histopathological Characteristics and Hormone Receptors in Breast Cancer
Authors: Mohammadi Kazhaleh , Salimi Mahdiyeh , Angaji S. Abdolhamid , Saniotis Arthur , Mahjoobi Foroozandeh
Published: December 2021

Background

Breast cancer (BC) is a heterogeneous disease that has different clinical outcomes. Bax-interacting Factor-1 (BIF-1) is a member of the endophilin B family that produces the pro-apoptotic BCL2-Associated X (BAX) protein in response to apoptotic signals. Lack of BIF-1 inhibits the intrinsic pathway of apoptosis and increases the risk of tumor genesis. The aim of the present study was to investigate the relationship between hormone receptors (ER, PR, HER2) status and different levels of BIF-1 gene expression in breast cancer patients.
Methods

BIF-1 gene expression was evaluated in 50 breast cancer tumors and 50 normal breast mammary tissues using SYBR Green Real Time RT-PCR technique. Multivariate and univariate analyses were used to evaluate the relationship between the prognostic significance of the BIF-1 gene using SPSS software. In this study, BIF-1 was selected as a candidate for a molecular biomarker and its expression status in breast cancer patients with hormone receptors (ER, RR, HER2) compared to patients without these hormone receptors.
Results

The study showed that the relative expression of BIF-1 gene in tissues of patients with hormone receptor in breast cancer compared to those without hormone receptor were not statistically significant. The expression levels of BIF-1 gene in different groups were evaluated for hormone receptor status. No significant relationship was found between BIF-1 gene expression and hormone receptors (ER, PR and HER2) (p> 0.05).
Conclusion

BIF-1 gene expression may be a useful prognostic marker in breast cancer.
Determinants of households’ livelihood diversification strategies to adapt with natural disasters: Evidence from ecologically vulnerable haor region of Bangladesh
Authors: Hoq Mohammad Shamsul , Uddin Md. Taj , Raha Shankar Kumar , Hossain Mohammad Ismail
Published: December 2021

The haor region of Bangladesh is exposed to a variety of natural disasters such as flash floods, seasonal floods, droughts, riverbank erosions, embankment breaches due to climate change, which impacts the haor people's lives and livelihoods. The study aims to assess the various livelihood strategies adopted by the haor households, as well as the factors that influence their decision to pursue more environmentally friendly and sustainable livelihood strategies. The primary data from the 300 haor households in Kishoregonj, Netrokona and Sunamgonj districts were collected with a multi-stage stratified random sample technique taking 100 of each district. We provide inimitable insight into the analysis framework for understanding sustainable rural livelihood, as well as empirical evidence of how livelihood resources, livelihood strategies, and livelihood outcomes are strongly interrelated. The study classified households’ economic activities into five distinct categories together with crop farming to cope with natural disasters. Among the livelihood options, crop plus livestock rearing is the most productive livelihood strategy for haor households. The findings revealed that the higher returning livelihood diversification strategies are significantly influenced by the household’s head age and education, dependency ratio, land holdings, household assets value, access to credit, annual income, membership of any organization, home to road, market, and haor distances, communication during the dry season, duration of waterlogged, and agro-ecology. In order to change the local context and enable poor households to establish more profitable livelihood strategies, policies should aim to promote the significant determinants of livelihood strategies, as well as ensure livelihood assets, a strong infrastructure, and minimize natural disasters.
The Accumulation of Essential Oils In Organ Culture of Acinos Graveolens Via Methyl Jasmonate And Salicylic Acid Exertion
Authors: Motafakkerazad Rouhollah , Soltani-Elired Vahideh , Tarigholizadeh Sarieh , Kosari-Nasab Morteza
Published: December 2021

The impact of Salicylic acid (SA) and Methyl jasmonate (MJ) on growth, and essential oil quantity and quality in organ culture of Acinos graveolens were investigated. In the present study, nodal segments were used as explants for shoot production using MS media with BA and NAA. Afterward, they were transferred to liquid MS media culture containing SA and MJ with 50, 100, and 150 µM and their combinations (SA25+MJ25, SA50+MJ25, SA25+MJ50, and SA50+MJ50). After three weeks, samples were collected to assess the morphological and some growth parameters, quantitative changes in pigment amounts as well as volatile contents. Accordingly, almost all treatments led to a notable decrease in growth parameters in comparison with control. The highest amount of Chl a, b and carotenoids were achieved by MJ100, SA50, and SA25+MJ50, respectively. In addition, GC-MS results indicated 38 components of volatile products mainly alkane hydrocarbons and sesquiterpenes. The major identified compounds were Decane, Eicosane, and Germacrene D. Altogether, results asserted that SA25+MJ25 and SA100 were more efficient in the enhancement of essential oil content among all treatments.
Comparative Analysis of The Kinomes of Plasmodium Falciparum, Plasmodium Vivax And Their Host Homo Sapiens
Authors: Adderley Jack , Doerig Christian
Published: December 2021

Background: Novel antimalarials should be effective across all species of malaria parasites that infect humans, especially the two species that bear the most impact, Plasmodium falciparum and Plasmodium vivax. Protein kinases encoded by pathogens, as well as host kinases required for survival of intracellular pathogens, carry considerable potential as targets for antimalarial intervention 1,2. To date, no comprehensive P. vivax kinome assembly has been conducted; and the P. falciparum kinome, first assembled in 2004, requires an update. The present study, aimed to fill these gaps, utilises a recently published structurally-validated multiple sequence alignment (MSA) of the human kinome 3. This MSA is used as a scaffold to assist the alignment of all protein kinase sequences from P. falciparum and P. vivax, and (where possible) their assignment to specific kinase groups/families.Results: We were able to assign six P. falciparum previously classified as OPK or ‘orphans’ (i.e. with no clear phylogenetic relation to any of the established ePK groups) to one of the aforementioned ePK groups. Direct phylogenetic comparison established that despite an overall high level of similarity between the P. falciparum and P. vivax kinomes, which will help in selecting targets for intervention, there are differences that may underlie the biological specificities of these species. Furthermore, we highlight a number of Plasmodium kinases that have a surprisingly high level of homology with their human counterparts and therefore not well suited as targets for drug discovery.Conclusions: Direct comparison of the kinomes of Homo sapiens, P. falciparum and P. vivax sheds additional light on the previously documented divergence of many P. falciparum and P. vivax kinases from those of their human host. We provide the first direct kinome comparison between the phylogenetically distinct species of P. falciparum and P. vivax, illustrating the key similarities and differences which must be considered in the context of kinase-directed antimalarial drug discovery, and discuss the divergences and similarities between the human and Plasmodium kinomes to inform future searches for selective antimalarial intervention.
Geometric Mediator Structures, Transition Dynamics and Force Constants
Authors: Koehler Dale. R.
Published: December 2021

It is shown in the present work that the distorted-space model of matter can describe conventional force-constants and transition-mediator structures. We use the verbiage “distorted” to communicate the concept of “energetic warping” to distinguish “spatial warping” from “classical matter warping”, although the concept of “matter” is in fact, in the present context, the “geometric distortion energy” of the spatial manifold itself without a classical “matter stressenergy source”. The “distorted-geometry” structures exhibit non-Newtonian features wherein the hole or core-region fields of the structures are energetically-repulsive (negative pressure), do not behave functionally in an r -4 manner and terminate at zero at the radial origin (no singularity). Near the core of the distortion the magnetic fields dominate the energy-densities of the structures thereby departing from classical particle-structure descriptions. Black-body radiation-emission and structural modeling lead to a description of transition dynamics and photonic entities.
Revealing Fano Combs in Directional Mie Scattering
Authors: Marmolejo Javier , Canales Adriana , Hanstorp Dag , Méndez-Fragoso Ricardo
Published: December 2021

The constructive interference of light reflecting on the inner surface of a dielectric sphere results in a rich Mie scattering spectrum. Each resonance can be understood through a quantum-mechanical analogy, while the structure of the full spectrum is predicted to be a series of Fano resonances. However, the overlap of all the different modes results in such a complex spectrum that an intuitive understanding of the full, underlying structure is still missing. Here we present a directional Mie spectrum obtained by selecting a particular polarization and direction of the scattering of levitating water droplets. We find a significantly simplified spectrum organized in distinct, consecutive Mie Fano Combs composed of equidistant resonances that smoothly evolve from wide Lorentzians into sharp Fano profiles. We then fully explain all these characteristics by expanding on the quantum-mechanical analogy. This makes it possible to understand Mie spectra intuitively without the need for computational simulations.
Pilot Remote Clinical Communication Skill Session During COVID-19 Pandemic: Medical Education in New Normal
Authors: Rasalingam Gajarishiyan
Published: December 2021

IntroductionClinical Communication teaching has relied heavily on face-to-face teaching using Patient Partners. The current situation with COVID-19 has led to lockdown, social isolation and travel difficulty. This leads to challenges in delivering this teaching. The study aim is to pilot a clinical communication teaching session remotely, using a virtual learning environment and video conferencing. This study evaluates the pilot about achieving learning outcomes on Musculo Skeleton disease and experience of student’s and patient partner.MethodsMixed qualitative and quantitative data are obtained through an online survey. The thematic framework is used to analyse the qualitative data and the descriptive statistics are used to evaluate the quantitative responses. Results The study provided satisfaction on proceeding this new pilot remote communication session to the routine medical curriculum, with 100% recommendation by the students. The majority of students had transformed their theoretical knowledge in the Musculo Skeleton disease system to consult with patient partners. The study also finds some gaps such as delays due to internet and device faults, limited time to build rapport with patients, nonverbal expressions are not being conveyed via the screen and difficulties in adapting to new remote sessions in short transition.ConclusionLooking into the future of new normal. Remote clinical communication session worked well during the pilot study. New innovatory methods in delivering remote teaching and more studies on different diseases topics should be implemented to analyse the sustainability and validity of the remote session for continuous delivery in medical education.