bluuebunny/crossref_metadata_2025 huggingface dataset:
Roadmap for implementing climate adaptation innovations in railway
Authors: Jägare Veronica , Juntti Ulla , Garmabaki Amir
Published: December 2023

This paper proposes a system-level innovation roadmap for implementing innovations for climate adaptation of railway infrastructure. The aim of this research was to explore, identify, and analyse the barriers and enablers related to implementing the CliMaint1 innovation.
The CliMaint innovation is a decision support system that will aid adaptation to climate change for railway infrastructure. To achieve the aim of the research, barriers and enablers related to five system innovation dimensions have been explored, identified, and analysed.
Two interview studies and a review of the literature have been conducted. In total, 45 experts from a population with knowledge in infrastructure and transportation networks have been selected and interviewed for the study. The interviews have been analysed and the related barriers and enablers for implementation associated to each system innovation dimension have been identified.
It was concluded that when identifying barriers and enablers to introducing new business models, two categories stand out: 1) barriers related to the external environment, e.g., policy and industry and low digitalisation readiness level, and 2) barriers related to the internal environment, e.g., tendering process, business models, and client-supplier relationships. The barriers and enablers concerning the implementation of the innovation is related to policy, regulations, process, digitalisation, business models, and finance. The findings concerning barriers and enablers has been used to propose a roadmap, suggesting appropriate measures to accelerate the implementation of the CliMaint innovation.
[1] www.ltu.se/climaint
Analysis of Malicious Files Gathering via Honeypot Trap System and Benchmark of Anti-Virus Software
Authors: BASER Melike , GUVEN Ebu Yusuf , AYDIN Muhammed Ali
Published: December 2023

In an era dominated by the pervasive integration of digital technologies, the surge in cyber threats is increasingly conspicuous. Cyber attackers employ malicious software (Malware) to compromise data integrity and exploit system resources. Tactics include transforming devices into remotely controlled assets or extorting ransom through data encryption. While end users commonly resort to antivirus software with signature-based detection, the protracted and dangered of malware detection necessitates alternative approaches. This study addresses this need by utilizing a honeypot trap system on Google Cloud to analyze suspicious files uploaded by attackers. Evaluated through a signature-based method, these files using 64 antivirus programs underscore the inadequacy of relying solely on this approach, with only three exhibiting success rates exceeding 90%. The majority, 61 antivirus programs, showed success rates predominantly below 70%. This underscores a crucial conclusion: sole reliance on signature-based security falls short in combating contemporary cyber threats. The study advocates for diverse detection techniques, independent or concurrent with signature-based methods, to fortify cybersecurity. The repository containing the honeypot-collected malicious files and Python script is publicly available on Github, serving as a valuable research resource.
Genomic diversity in functionally relevant genes modifies neurodevelopmental versus neoplastic risks in individuals with germline PTEN variants
Authors: Eng Charis , Kim Adriel , Yehia Lamis
Published: December 2023

Individuals with germline PTEN variants (PHTS) have increased risks of the seemingly disparate phenotypes of cancer and neurodevelopmental disorders (NDD), including autism spectrum disorder (ASD). Etiology of the phenotypic variability remains elusive. Here, we hypothesized that decreased genomic diversity, manifested by increased homozygosity, may be one etiology. Comprehensive analyses of 376 PHTS patients of European ancestry revealed significant enrichment of homozygous common variants in genes involved in inflammatory processes in the PHTS-NDD group and in genes involved in differentiation and chromatin structure regulation in the PHTS-ASD group. Pathway analysis revealed pathways germane to NDD/ASD, including neuroinflammation and synaptogenesis. Collapsing analysis of the homozygous variants identified suggestive modifier NDD/ASD genes. In contrast, we found enrichment of homozygous ultra-rare variants in genes modulating cell death in the PHTS-cancer group. Finally, homozygosity burden as a predictor of ASD versus cancer outcomes in our validated prediction model for NDD/ASD performed favorably.
Cross-talk between hepatokines as Liver indused-exercise factors and organokines
Authors: rad reza sabzevari
Published: December 2023

Exercise not only improves the capacity of the skeletal muscles that perform contractions, but also provides health benefits and prevents a number of chronic diseases caused by physiological and biological changes throughout the body. For decades, intensive research has been carried out into the “exercise factors” that mediate these positive effects. In particular, skeletal muscle tissue has been studied as a source of circulating exercise factors and several myokines have been identified. However, Exercise also affects other tissues. The liver plays an important role in the tissues that store and use energy as well as it is very active during exercise and ensures the maintenance of energy homeostasis. Recently, a novel group of Liver indused-exercise factors termed hepatokines has emerged. Hepatokines can act in an autocrine/paracrine manner on the liver and as endocrine factors on brain, endothelium, adipose tissue, pancreas, heart, intestine, and skeletal muscle. In most cases, an acute bout of exercise increases the systemic concentration of hepatokines (FGF21, ANGPTL4, Follistatin, Selenoprotein P, HSP72 ,IGFBP, fetuin-A, fetuin-B, Hepassocin, Activin E, Chemerin, Adropin) and this factors released from the liver and increased in the bloodstream during or in the recovery after an exercise bout. It should be noted that in addition to liver tissue, there are also other hepatokines secreted and released by other tissues such as brain, adipocytes, intestine, heart, osteoblasts and melanoma. In this narrative review, we evaluate this new group of exercise factors focusing on the regulation and potential function in exercise metabolism and adaptations .These hepatokines may convey some of the beneficial whole-body effects of exercise and cross-talk with organokines and could ameliorate metabolic diseases, such as obesity or type 2 diabetes.
Climate change perceptions and adaptation by Sebei pastoralists in Mt Elgon, Uganda
Authors: Siya Aggrey , Varela Elsa , Batumike Rodrigue , Cuni-Sanchez Aida
Published: December 2023

Pastoralists’ sedentarisation and agriculturalization might increase their vulnerability to climate change impacts, but few studies have investigated if this is the case in mountain areas. In Uganda, little is known about how Sebei pastoralists have perceived and adapted to such changes. In this study, we used focus-group discussions with village elders to assess local perceptions regarding climatic changes, impacts and adaptive strategies used. In all villages, study participants reported changes in the amount and distribution of rainfall, fog and temperatures, with negative impacts on fodder availability, milk production and increase of pests and diseases. Study participants mentioned using several adaptation strategies with regard to animal rearing, crop farming and livelihood diversification. Among others, participants reduced herd size, migrated longer distances, stored wild grass, used crop residues as feed and increased ‘self-medication’ of their cattle. Access to funds, markets and technical advice were the main barriers to adaptation identified. Institutional support- now only focused on improved breeds – should consider the multiple strategies used by pastoralists, and increase opportunities for mutual learning
Between-Word Processing and Text-Level Skills Contributing to Fluent Reading of (Non)Word Lists and Text
Authors: Viersen Sietske van , Altani Angeliki , de Jong Peter F. , Protopapas Athanassios
Published: December 2023

This study investigated (1) sequential (between-word) processing efficiency at various points during development, (2) its importance within a range of measures typically used to assess reading fluency, and 3) how subskills typically associated with word-level and text-level processes may interact and uniquely contribute to various reading fluency outcomes. The sample included 139 intermediate-level (Grade 3, n = 78) and more advanced (Grade 5, n = 61) readers of Dutch. Word-level subskills covered within-word processes and sequential between-word processing efficiency. Subskills associated with text-level processing were vocabulary and syntactic skills. Fluency measures included simple and complex lists of words and nonwords, and a text. Data were analyzed through hierarchical regressions and commonality analyses. The findings extend the importance of sequential (between-word) processing efficiency for fluent reading of simple word lists and texts, after controlling for within-word processes, to complex word lists and texts as well as lists of nonwords. The findings hold for both intermediate-level and more advanced readers and, as expected, the contribution of between-word processing increased with reading-skill level. Effects of vocabulary were generally absent, aside from a small effect on text reading fluency in Grade 3. Effects of syntactic skills were not found, not even in more advanced readers. The results support the idea that once efficient individual word recognition is in place, further fluency development is driven by more efficient between-word processing. They also confirm that vocabulary may be less prominent in processing mechanisms underlying fluent word identification in transparent languages, across reading levels.
Research on the Innovation of Throwing Techniques for High-Pole Embroidered Balls and the Sustainable Development of National Sports
Authors: jun Xu Shijun , Cong Zeng , Pei Yang , Yu Wei , yun Wang
Published: December 2023

Research purpose: This study aims to understand the historical and cultural origins of throwing embroidered balls and inherit national sports culture, analyze the existing theory of high-pole throwing embroidered ball technique, combine technological innovation with the application of technological information, improve the competitive level of high-pole throwing embroidered ball sports, and improve competition rules and referee law enforcement. Research methods: Utilizing methods such as literature review and mathematical statistics, this study aims to elucidate the evolutionary history of embroidered ball culture and the development processes involved in the act of throwing embroidered balls. Based on the results of the high-pole throwing embroidered ball competition during the 12th and 13th Guangxi Student Games, this study investigated the controversies surrounding traditional throwing techniques within the realm of theory and competition rules. Result: The current competition rules mainly include unclear throwing control lines, which can lead to misjudgments; the controversy regarding the number of hits determined by the referee’s naked eye remains unresolved; the quality and specifications of the balls used in the competition are not uniform; the existing throwing techniques lack guiding significance for high-level competitions; and innovative throwing techniques can be divided into three matching scenarios, with the optimal throwing angle range being between 64° < α < 72°, with manual rotation being the best option, and with the range of throwing speed being between 13.04 m/s < v < 13.70 m/s. Conclusion and suggestion: (1) Integrate the development of ethnic sports with the inheritance of ethnic sports culture. (2) Enhance the competitive sports level through technological innovation. Consider adopting the concept of an effective throwing range instead of casting a point to improve hit rates. Modify the trajectory of the throwing ball by ensuring the arc’s appex does not exceed the circle plane, thus reducing running distance and throwing time. At a shooting angle of 66°, v ≈ 13.70 m/s reaches its maximum value, and when it reaches 64° downward, v is 13.04 m/s; Up to 72°, v is 13.17 m/s. (3) Unify the equipment standards for the competition venue. Improve the competition level and the competition rules. Promote the development of high-pole embroidered ball competitions to a higher level. Pursuing standardization and internationalization is a strategic approach for achieving the sustainable development of this national sport.
The research on fracture and structural trap of the Weixinan Sag, Beibuwan Basin, South China Sea
Authors: Kui Chen , Yushuang Zhu , Mao Li , Shaopeng Zhu , Chao Yuan , Chun Xiu , Chunning Li
Published: December 2023

The Weixinan Sag in Beibuwan Basin is a pilot area of the offshore exploration and development integrated technology. The main oil bearing layers, one member of Liushagang formation and third member of Weizhou formation, develop many fracture systems and structural traps. The key factors of the offshore exploration and development integrated technology are"the fracture research"and "the effectiveness of structural trap". Fracture research includes the study of the geometry, dynamics, kinematics characteristics of fracture, and the division of fracture system. The effectiveness of structural trap include analogical studies on the structural characteristics of traps, quantitative studies on fault lateral sealability, fault vertical sealability, and prediction technology of oil column height. Comprehensive the relationship of the law of oil and gas distribution,the differential fracture system in the internal of the No. 2 fracture zone, and the effectiveness research of traps, fault-controlled reservoir laws and the dominant fault-controlled reservoir mode are obtained. The research on fracture and trap of offshore integrated exploration and development has been successfully applied in the Weixinan Sag. The 37 of 45 development evaluation wells have been drilled successfully and the drilling success rate is 82%. It has promoted the ODP implementation of 5 oilfields, the adjustment implementation of 8 oilfields and made important contribution to the increase of reserves and production in the Weixinan Sag.
Surgical treatment of severe Posterior Reversible Encephalopathy Syndrome (PRES) with brainstem involvement: Systematic Review and Illustrative Case
Authors: Lala Ronahi , Cornelius Jan Frederick , Hänggi Daniel , Muhammad Sajjad
Published: December 2023

Background and Purpose – Untreated hypertension can lead to severe posterior reversible encephalopathy syndrome (PRES), that is a reversible intracranial complication. Involvement of posterior fossa structures including brainstem is extremely rare but life-threatening condition if not treated properly and timely. Here we review different clinical aspects of surgically treated cases of PRES with brainstem involvement and present an illustrative case. Methods – We searched the MEDLINE electronic database for studies on PRES with brainstem involvement. Hypertensive crisis as a cause of PRES and surgical treatment of PRES were inclusion criteria. We show a successfully treated case with this constellation. Finally, we summarize the data in current literature to provide treatment recommendation for this rare devastating condition. Results – We found 5 reports with a total of 7 patients of PRES with brainstem involvement which were treated by posterior fossa decompression. Hypertension or malignant hypertension were common at onset of PRES. 85% of all cases were females and one of these cases was a 3-year-old girl. 71% of patients had a mRS ≤ 3 at discharge. Conclusions – A clinically manifest brainstem PRES can be alleviated successfully through posterior fossa decompression so the ischemic and oedematous brain tissue can regenerate without further injury due to mechanical compression.
Dynamic analysis and experimental research of the novel needle punched rubber bark detection device
Authors: Fan Bo , Chen Warong , Cao Jianhua , Zhang Yishan , Xiao Suwei , Su Xin
Published: December 2023

A novel NPRBDD is developed to obtain suitable cutting depth of rubber bark in the harvesting process of natural rubber. Based on experimental data and the optical microscope photographs of slice diagram of the pinhole in rubber bark, the acupuncture-detection process of NPRBDD can be divided into three stages of pre puncture stage, squeezing stage and puncture stage. The main bending deformation of probe occurs in the squeezing stage, which will affect the detection accuracy of NPRBDD. Regarding the motion characteristics of the probe in the squeezing stage, a new expression of finite element method are proposed and used to establish nonlinear dynamic variational equations of probe. And a fractional order model was used to fit the force on the probe tip. According to numerical simulation, the probe of NPRBDD is selected that stainless-steel-316L probe with 25mm length and 0.25mm radius. Then, through field experiments, the validity of NPRBDD is validated, and it can be found that the stability of detection result of NPRBDD is higher than that of traditional measurements.
Hidden blood loss and its risk factors after hip reconstruction in children
Authors: Yang Jiafei , Jiang Hua , Yu Song , Gu Huajian , Du Jun , Zhuo Yingquan , He Kunfeng
Published: December 2023

Objective: There were few reports in the literature about the hidden blood loss (HBL) after modified Pemberton osteotomy(PO) for children. To evaluate HBL and its risk factors among children following PO for Developmental Dysplasia of the Hip(DDH).
Methods: A retrospective analysis was made on the clinical data of 42 patients(58 hips) underwent PO surgery from March 2020 to March 2023. Serial complete blood count assays were performed consecutively on the day of admission and 4 days after surgery. Recording preoperative and postoperative hematocrit to calculate HBL according to Gross formula and analyzing its related factors. Pearson correlations, Spearman correlations and multivariate liner analysis were used to find association between patient characteristics and HBL.
Result:The mean HBL was 278.06±291.00 mL, accounting for 67.17% of total blood loss. It indicated that the amount of HBL was much higher than we expected. According to the model of multiple linear regression analysis, Patient weight(P＜0.001), surgical duration(P＜0.001) were independent risk factors contributing to the HBL.
Conclusions:HBL following PO for DDH was significant and should be recognised as a detrimental factor to patient safety during the perioperative period, especially in patients with high weight and long surgical duration.
Level of evidence: III
RETRACTED: A Novel Weight-based Fish School Search Approach for Hierarchical Network Clustering
Authors: Ibrahim Abuzer Hussein , BOUDREF Mohamed Ahmed , BADIS Lyes
Published: December 2023

The authors have requested that this preprint be removed from Research Square.
Urinary cadmium concentration is associated with the severity and clinical outcomes of COVID-19: a bicenter observational cohort study
Authors: Chiu Li-Chung , Lee Chung-Shu , Hsu Ping-Chih , Li Hsin-Hsien , Chan Tien-Ming , Hsiao Ching-Chung , Kuo Scott Chih-Hsi , Ko How-Wen , Lin Shu-Min , Wang Chun-Hua , Lin Horng-Chyuan , Chu Pao-Hsien , Yen Tzung-Hai
Published: December 2023

Background
Cadmium exposure can cause oxidative stress, induce inflammation, inhibit immune function, and therefore has significant impacts on the pathogenesis and severity of many diseases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can also provoke oxidative stress and the dysregulation of inflammatory and immune responses. This study aimed to assess the potential associations of cadmium exposure with the severity and clinical outcomes of patients with coronavirus disease 2019 (COVID-19).
Methods
We performed a retrospective, observational, bicenter cohort analysis of patients with SARS-CoV-2 infection in Taiwan between June 2022 and July 2023. Cadmium concentrations in blood and urine were measured within 3 days of the diagnosis of acute SARS-CoV-2 infection, and the severity and clinical outcomes of patients with COVID-19 were analyzed.
Results
A total of 574 patients were analyzed and divided into a severe COVID-19 group (hospitalized patients) (n = 252; 43.9%), and non-severe COVID-19 group (n = 322; 56.1%). The overall in-hospital mortality rate was 11.8% (n = 68), and 149 patients (26%) required invasive mechanical ventilation. The severe COVID-19 patients were older, had significantly more comorbidities, and significantly higher neutrophil/lymphocyte ratio, C-reactive protein, and interleukin-6 than the non-severe COVID-19 patients (all p < 0.05). Both blood and urine cadmium concentrations were significantly higher in the severe COVID-19 patients than in the non-severe COVID-19 patients. Among the severe COVID-19 patients, those in higher urine cadmium/creatinine quartiles had a significantly higher risk of organ failure (i.e., higher APACHE II and SOFA scores), higher neutrophil/lymphocyte ratio, lower PaO2/FiO2 requiring higher invasive mechanical ventilation support, higher risk of acute respiratory distress syndrome, and higher 60-, 90-day, and all-cause hospital mortality (all p < 0.05). Multivariate logistic regression models revealed that urine cadmium/creatinine was independently associated with severe COVID-19 (adjusted OR 1.648 [95% CI 1.064–2.552], p = 0.025), and that a urine cadmium/creatinine value > 2.05 µg/g had the highest predictive value (adjusted OR 5.391, [95% CI 1.127–25.794], p = 0.035).
Conclusions
Urine cadmium concentration in the early course of COVID-19 could predict the severity and clinical outcomes of patients and was independently associated with the risk of severe COVID-19.
Residents’ experiences during a hydrogen sulfide crisis in Carson, California
Authors: Quist Arbor J.L. , Hovav April , Silverman Alexander , Shamasunder Bhavna , Johnston Jill E.
Published: December 2023

Background
In early October 2021, thousands of residents in Carson, California began complaining of malodors and headaches. The odor was identified as hydrogen sulfide (H2S), a noxious odorous gas. H2S was measured at concentrations up to 7000 parts per billion (ppb) and remained above California’s acute air quality standard of 30 ppb for a month, with intermittent elevations continuing for 3 months. After 2 months of malodor in this environmental justice community, the H2S was attributed to a warehouse fire. Research has yielded conflicting results on the health effects of H2S exposure at levels that were experienced during this event. There remains a gap in understanding how people perceive and experience odor emergencies such as this H2S event.
Methods
Through a community-academic partnership, we conducted 6 focus groups in Carson with 33 participants who resided in the Carson area during the crisis. We sought to understand how this incident affected residents through facilitated discussion on topics including information acquisition, impressions of the emergency response, physical and mental health symptoms, and ongoing impacts.
Results
The majority of participants were women (n = 25), identified as Latina/o (n = 19), and rent their homes (n = 21). Participants described difficulty obtaining coherent information about the emergency, which resulted in feelings of abandonment. Most participants felt that local government and health care providers downplayed and/or disregarded their concerns despite ongoing odors and health symptoms. Participants described experiencing stress from the odors’ unknown health effects and continued fear of future odor incidents. Residents sought to take control of the crisis through information sharing, community networking, and activism. Participants experienced longer term effects from this event, including increased awareness of pollution and reduced trust in local agencies.
Discussion
This study demonstrates the necessity of clear, comprehensive, and prompt responses by relevant decisionmakers to chemical emergencies to appropriately address residents’ fears, curb the spread of misinformation, and minimize adverse health effects. Participant responses also point to the benefit of supporting horizontal community networks for improved information sharing. By engaging directly with community members, researchers and disaster responders can better understand the various and complex impacts of chemical disasters and can improve response.
Relationship Between Leadership Behaviour and Firm Performance in Ready Made Garments (Rmg) Industry of Bangladesh
Authors: Tareque Alam , Islam Prof. Nazrul
Published: December 2023

Purpose
The primary objective of this research is to investigate and elaborate on the relationship between leadership behaviour and firm performance in the context of Bangladesh RMG (Ready-Made Garments) firms. The study aimed to contribute to the existing literature by exploring the role of leadership behaviour in the competitive advantage process, addressing gaps in understanding within the RMG industry.
Design/Methodology/Approach:
The research employs a mixed-method approach, incorporating qualitative and quantitative research methods. The conceptual model is developed through an extensive literature review and subsequently tested, refined, and validated. The empirical analysis involves 400 target respondents, and data is processed using PLS structural equation modelling principles. This includes structural path analysis, hypothesis testing, mediation, and moderation analyses.
Findings:
Empirical findings align with the resource-based view, confirming that Leadership Behaviours are intangible resources. Furthermore, the study identifies relationship-oriented behaviour as the most significant influence on the relationship between leadership behaviour and firm performance.
Originality:
This research delves into the Resource View's black box in firms. It establishes Dynamic Capabilities as a theoretically well-founded and valuable construct for understanding the leadership behaviour of strategic management.
Practical Implications:
providing insights into how leadership behaviour can impact firm performance. Identifying Relation Behaviours as particularly influential suggests that fostering positive relationships within the organisation may be a key strategy for leaders to enhance overall performance.
Social Implications:
the findings may have implications for workplace relationships, employee satisfaction, and potentially broader societal aspects influenced by the performance of RMG firms.
Effect of Fertilizer Type and Variety on Growth and Yield of Potato (Solanum tuberosum) at South Omo Zone, Southern Ethiopia
Authors: Metaferia Bantayehu Muluneh , Faye Kumsa Dida , Ashagire Semu Yetaferu
Published: December 2023

The main problem in Ethiopia is food insecurity. The potato has been recognized by the Ethiopian government as a strategic crop to increase food security and farmers' incomes. Potato yields are strongly influenced by agronomic practices such as crop management, fertilizer source and variety. The country's productivity is far below than of the world. Therefore, this study aimed to investigate the effect of fertilizer source and potato variety on growth and tuber yield. The field trial was carried out in a factorial design with the RCBD and repeated three times in each case. The experiment included four fertilizer sources (Control, DAP, NPS and NPSB) and four potato varieties (Local, Gudenie, Belete and Jalenie). During the experiment: data on growth and yield parameters were collected. Experimental results showed that the interaction between fertilizer source and variety was very significant in terms of physiological maturity, number of main shoots, average tuber weight, marketable tuber weight in t/ha and non-marketable tuber yield in t/ha. The interaction of NPBS mixed with the Jalenie cultivar was found to provide a maximum commercial tuber yield of 23.04 t/ha. Because of this, we were advised to use NPSB and urea fertilizer with variety Jalenie to get the maximum marketable tubers yield under condition of little rainfall and a prolonged dry period.
Evaluating Normative Learning in Generative AI for Robust Medical Anomaly Detection
Authors: Bercea Cosmin , Wiestler Benedikt , Rueckert Daniel , Schnabel Julia
Published: December 2023

In Generative Artificial Intelligence (AI) for medical imaging, normative learning involves training AI models on large datasets of typical images from healthy volunteers, such as MRIs or CT scans. These models acquire the distribution of normal anatomical structures, allowing them to effectively detect and correct anomalies in new, unseen pathological data. This approach allows the detection of unknown pathologies without the need for expert labeling.
Traditional anomaly detection methods often evaluate the anomaly detection performance, overlooking the crucial role of normative learning. In our analysis, we introduce novel metrics, specifically designed to evaluate this facet in AI models. We apply these metrics across various generative AI frameworks, including advanced diffusion models, and rigorously test them against complex and diverse brain pathologies. Our analysis demonstrates that models proficient in normative learning exhibit exceptional versatility, adeptly detecting a wide range of unseen medical conditions.
Set Ablaze Yet Not Consumed: Tenure Seeking Blackwomxn and Black Feminist Pedagogical Approaches to Teaching and Mentoring during COVID-19
Authors: Raya Petty  , LaWanda W. M. Ward
Published: December 2023

This study was designed to explore the personhood affirming approaches Blackwomxn faculty incorporate in teaching and mentoring Students of Color and the impact of COVID-19 on their efforts. Using a Black feminist perspective, we centered the pedagogical practices of Blackwomxn faculty to examine their unique experiences and interactions with Students of Color. Their narratives reflect how Blackwomxn faculty contribute worldviews that challenge Eurocentric, patriarchal and heteronormative pedagogical practices and how their approaches to teaching and mentoring demonstrate what we label as contemporary anti-slavery rebel behavior.
Tired of Always Grinding: Black Womxn Faculty’s Experiences During COVID-19
Authors: Logwood Dyann , Ali Sadaf , Barragan Cassandra
Published: December 2023

The dueling pandemics of COVID-19 and racism brought to light the inequities Black womxn face in higher education in regard to service burdens. We argue Black womxn are overextended and suffering in their careers and lives as a result of this taxation. Methods. A sample of 191 faculty at a predominantly White university (PWI) in the Midwest United States responded to a survey about attitudes towards service obligations, sense of belonging, and community culture, centering on race, ethnicity, and gender as well as the impact of COVID on service obligations. Due to the limited number of Black womxn participants, their characteristics are only reported in the overall data based on their identity or race. Findings. Gender, race, and feeling a part of the community were found to be significant predictors of voluntarily taking on student-centered service related to identity and being asked to take on service related to identity. Black womxn faculty were approximately 78 times more likely than White male faculty to volunteer for identity-based service. Black womxn faculty were approximately 473 times more likely than White male faculty to be asked to participate in identity-based service. The COVID-19 pandemic and racism have had a significant impact on everyone's lives, but it has been especially difficult for BIPOC and Black women. They have faced emotional, spiritual, and physical challenges. Therefore, it is crucial for higher education institutions to create safe spaces where Black women can live their best and most productive lives.
Superfluid response of two-dimensional filamentary superconductors
Authors: Venditti Giulia , Maccari Ilaria , Jouan Alexis , Singh Gyanendra , Budhani Ramesh C. , Feuillet-Palma Cheryl , Lesueur Jérôme , Bergeal Nicolas , Caprara Sergio , Grilli Marco
Published: December 2023

Different classes of low-dimensional superconducting systems exhibit an inhomogeneous filamentary superconducting condensate whose macroscopic coherence still needs to be fully investigated and understood. Here, we present a thorough analysis of the superfluid response of a prototypical filamentary superconductor embedded in a two-dimensional metallic matrix. By mapping the system into an exactly solvable random impedance network, we show how the dissipative (reactive) response of the system non-trivially depends on both the macroscopic and microscopic characteristics of the metallic (superconducting) fraction. We compare our calculations with resonant microwave transport measurements performed on LaAlO_33/SrTiO_33 heterostructures over an extended range of temperatures and carrier densities finding that the filamentary character of superconductivity accounts for unusual peculiar features of the experimental data.
The interconnections of workplace spirituality, mindfulness, subjective well-being, and task performance: A study using structural equation modeling
Authors: Abdullah Alruwayti Hatim , M. M. Sulphey
Published: December 2023

The wellness of employees is one of the most important aspects of a successful business. Therefore, workplace spirituality, mindfulness, and subjective well-being are highly valued by businesses. This study examined the relationship between workplace spirituality, mindfulness, and subjective well-being on task performance. Online responses from 394 Saudi Arabians gainfully employed in different industries were randomly gathered using four standardized questions. The respondents’ gender, age, experience levels, and industries were diverse, which created a wide and diverse sample. The study looked at common method bias using Harman’s single-factor test. With a total variance of 25.86%, the measured value is below the widely recommended 50% limit. This demonstrated that common method bias had no significant effect. Since all the fit indices have robust fit, the proposed model qualifies for conducting structural equation modeling. The results revealed a significant positive relationship, at a 0.01 level, between spirituality and subjective well-being (t = 3.77, < 0.05) and between spirituality and task performance (t = 3.27, < 0.05). In addition, a significant positive relationship was found between mindfulness and subjective well-being (t = 3.48, < 0.05) and mindfulness and task performance (t = 4.16, < 0.05). Another significant positive relationship existed between subjective well-being and task performance (t = 4.02, < 0.05). This indicates that subjective well-being and mindfulness reinforce employee performance. Also, workplace spirituality and mindfulness enhance both subjective well-being and performance. This finding provides additional evidence and opportunities to address issues related to employee performance.
Acknowledgment This study is funded by Prince Sattam Bin Abdulaziz University under a project numbered PSAU/2023/1444.
Análise de livros didáticos do sexto ano – PNLD (Brasil, 2020) quanto à temática da paleontologia
Authors: Da Costa Carolina Farias da Costa Farias , Scheid Neusa Maria John
Published: December 2023

O material mais utilizado por alunos e professores da escola pública é o Livro Didático (LD). Devido ao fato de ser um material distribuído gratuitamente, acaba sendo a principal, senão a única, fonte de consulta. Diante disso, aponta-se a relevância do LD como recurso importante e expressivo para a formação dos alunos, nomeadamente de escolas públicas. O ensino da Paleontologia não trata apenas de estudar dinossauros, como se pensa; muito além disso, a Paleontologia explana questões evolutivas de animais, de plantas e do Planeta Terra. Daí parte a sua importância de ser bem-vista e discutida com os alunos. Segundo a Base Nacional Comum Curricular (BNCC), o estudo do tema da Paleontologia é apresentado no sexto ano do Ensino Fundamental. Sendo assim, a análise se dá nos livros aprovados pelo Programa Nacional do Livro Didático (PNLD, 2020) deste nível. Foram analisados, no total, nove coleções, e, a partir do estudo realizado nos LDs, pode-se identificar que a maioria dedica apenas uma página para apresentação do referido tema, por meio de exposições breves e diretas que não possibilitam aos alunos e professores uma discussão mais apurada do tema envolvendo a paleontologia, pois há pouca informação. Conclui-se que o LD apresenta uma discussão bem superficial e/ou incompleta sobre o tema, necessitando que sejam feitos mais estudos para que a abordagem de conceitos de Paleontologia seja aperfeiçoada nesse crucial material didático.
Políticas públicas de inovação: Um estudo em localidades pouco desenvolvidas
Authors: Santos Irllas Evelline de Carvalho , Silva Glessia
Published: December 2023

Este artigo tem como objetivo compreender se as políticas públicas de inovação estaduais são adequadas ao desenvolvimento de localidades pouco desenvolvidas. Especificamente: analisar as políticas de inovação; identificar o propósito de desenvolvimento por trás das políticas; e entender o contexto local de desenvolvimento. O contexto de aplicação do estudo foi o Estado de Sergipe e a estratégia de pesquisa o estudo documental, com uso de documentos dispostos no site do IBGE e nos sites oficiais dos municípios e Estado de Sergipe. Também foram realizadas entrevistas com gestores públicos ligados às secretarias do Estado. As evidências foram analisadas por meio de análise de conteúdo qualitativa. Os resultados demonstraram que as políticas públicas de inovação não são adequadas ao contexto de localidades pouco desenvolvidas por não prestarem atenção às necessidades da população e ao contexto local. Como contribuição, espera-se avançar na discussão das políticas de inovação em contextos pouco desenvolvidos e que os insights gerados neste artigo auxiliem os formuladores de políticas a elaborarem políticas de inovação mais alinhadas às necessidades locais.
Intraregional shifts in Entrepreneurial Activity of Kemerovo Region – Kuzbass during Pandemic and Geopolitical Changes of 2020–2022
Authors: Rogova Kseniya , Sycheva-Peredero Ol'ga
Published: December 2023

Entrepreneurial activity has a serious impact on the development of regions and municipalities, especially remote, peripheral ones. The most important aspect of the small and medium-sized enterprises’ activities study in the region is the analysis of differences between territories in the levels of entrepreneurial activity, as well as the assessment of relevant processes dynamics in various external conditions. The purpose of the study is to identify intraregional differences in the entrepreneurial activity of the region, to assess the nature and significance of their changes based on the materials of the Kemerovo Region – Kuzbass in 2020–2022. The indicator of the number of small and medium-sized enterprises normalized per 10 thousand people was used, as well as descriptive statistics methods, paired samples t-test, pair and rank correlation coefficients. In 2020–2022, inter-municipal fluctuations in entrepreneurial activity practically did not depend on the population density or the spatial position of the municipality. The agglomeration factor did not contribute to a faster recovery of the medium-sized enterprises’ sector. It was revealed that remote peripheral areas are not outsiders in terms of entrepreneurial activity, which contradicts existing theoretical concepts. The minimum entrepreneurial activity is observed in small towns and rural areas adjacent to the cities of the Kuzbass agglomeration, which can be attributed to different possibilities of consumer demand migration, but requires further research.
What water supply system research is needed in the face of a conceivable societal collapse?
Authors: van Thienen Peter , Chatzistefanou Georgios Alexandros , Makropoulos Christos , Vamvakeridou-Lyroudia Lydia
Published: December 2023

The world grapples with immediate crises like COVID-19, Russia's invasion of Ukraine, floods, droughts and wildfires. However, a longer-term crisis looms due to humanity's overstepping of planetary boundaries and its disruptive consequences. Growing awareness of the potential collapse of societies due to planetary boundary violations has prompted increased attention in the scientific literature. In the water sector, where infrastructure built today might persist during a future collapse, we must therefore ask ourselves how a (basic) level of water supply can be maintained in a collapsing society. This paper explores this question and proposes research directions to address it in the short to medium term. Despite the seeming remoteness of a societal collapse scenario, it is imperative to incorporate it urgently into water infrastructure research and planning.
Sentimentos que atravessam a inserção profissional docente
Authors: Cruz Giseli Barreto da , Batalha Cecília Silvano , Campelo Talita da Silva
Published: December 2023

O artigo discute parte de uma pesquisa que analisou as possibilidades e os desafios da indução entre pares para o agir e o reagir de professores que estão em seus primeiros anos de exercício profissional. Inserida no campo da narrativa enquanto atividade (auto)biográfica, conduziu-se na perspectiva da pesquisa-formação como estratégia de indução docente. Teoricamente, fundamenta-se na compreensão de indução docente enquanto processo sistemático e intencional de acompanhamento formativo do professor iniciante orientada pelos princípios epistêmico-formativo da pesquisa narrativa. Com base nas análises, discutem-se as dificuldades e os desafios enfrentados por professores iniciantes durante a sua inserção profissional. Considerou-se que apesar do sentimento de angústia e insegurança, as narrativas não apontam para desistências, porém deixam ver sentidos que se configuram em aspectos que atravessam dois polos opostos – da frustração à ação.
“2D, 3D QSAR and Pharmacophore Identification of Thieno[3,2-d]pyrimidines
as Cholesterol inhibitors”
Authors: Amrutkar Rakesh D. , Jain Kishor S
Published: December 2023

Introduction::

The present study reveals the 2D, 3D-QSAR analysis of Thieno[3,2-d]pyrimidine to expressed the biological activity against Cholesterol,
structurally different ligands can fit to common receptor site and safety consideration of the said chemical entities are good describe by
Pharmacophore models.

Methods::

The organic exercises of the atoms were changed over into log IC50. The measurably huge of 2D-QSAR and 3D QSAR models are r2 = 0 .9762,
q2 = 0.9379 and internal (q2 = 0.8837) and external (predictive r2 = 0.9162) respectively. 2D QSAR studies revealed that the Positive coefficient
value of Quadrupole2 and Negative coefficient value of T_2_Cl_7 descriptors were major contributing descriptors.

Results::

2D QSAR studies revealed that Positive coefficient value of Quadrupole2 and Negative coefficient value of T_2_Cl_7 descriptors were major
contributing descriptor. The 3D QSAR models indicates that steric and electrostatic effects primarily find out the binding affinities.

Conclusion::

The best model obtained from the QSAR analysis, some newer compounds of same series were developed having the good activity than the earlier
compounds have been reported
An Exhaustive Review on Recent Trends in Analytical Methods: Development
Strategies and Recent Applications
Authors: Chaudhary Tanu , Kumar Akshay , Raj Naman Deep , Sarma GS , Dawange Shubham , Singh Dilpreet
Published: December 2023

API analysis plays an important role in nourishing the quality, safety, efficacy, and potency of bulk drugs and pharmaceutical formulations.
Increased drug products in the market lead to increased demand for new analytical techniques for Active Pharmaceutical Ingredient (API) analysis.
During the past decades, method developments were necessitated for drug impurities, excipient profiling, and testing for biopharmaceuticals like
dissolution and bioavailability. Moreover, advancements in the pharmaceutical industries necessitate upgrading newer technologies like analytical
Quality by Design (QbD) and artificial intelligence. This review focused on analytical method development and its official guidelines provided by
various regulatory bodies including ICH, US-FDA, AOAC, and USP. Moreover, this present art also states various validation and system
parameters along with their applicability and recommended range. The critical appraisal of analytical technologies for performing various API
analyses was also written in a scientific manner. Moreover, applications in recent trends in pharmaceutical industries as well as research were also
documented. Hence, this review provides sufficient information for the readers for in-depth information starting from scratch to higher
technologies for developing analytical methods and recent trends in the pharmaceutical industry.
To Shed Light on the Association between Poor Ergophthalmologic Practices
and Computer Vision Syndrome
Authors: Hardatt Dakshita , Singh Gurvinder , Kaur Navneet , Pethekar Akash J , Gupta Sumeet , Dhanawat Meenakshi
Published: December 2023

Background::

Computers play a vital role in people's lives because of their great precision, speed, and accuracy, as well as their ability to provide timely updates.
A cascade of ocular and extraocular symptoms in computers or electronics leads to Computer Vision Syndrome. Ergonomics is the science of
fitting job demands and workplace environments to the capabilities of the population. The use of a computer increases the risk of musculoskeletal
issues, particularly in the upper extremities.

Methodology::

The following research article elaborates on the surveys that were carried out in Maharishi Markandeshwar Deemed to be University Mullana, with
701 participants. Data were collected using the computer vision syndrome questionnaire and the ergonomics questionnaire for a duration of 6
months.

Results:

The most prevalent symptom of CVS occasionally was found to be a headache (503 participants=71.7%), followed by eye heaviness and eye pain
(483 participants=68.9%), burning sensation, itching and tearing (414 participants=59%), red eyes (361 participants=51.4%), foreign bodies (319
participants=45.5%), dryness (281 participants=40%), blurred and double vision (266 participants=37.9%), increased sensitivity to light and
colored halos (249 participants=35.5%), and difficulty focusing (299 participants=42.6%).

Conclusion::

All symptoms of CVS suffered by the participants were on an occasional basis, constituting the majority and the most common CVS symptom as
headache. In assessing the ergonomics, all participants experienced pain at least in one extremity and the majority of participants had their back
bent while working with electronics.