bluuebunny/crossref_metadata_2025 huggingface dataset:
Total Phenolic, Flavonoid, and LC-MS Analysis of the Ethanolic Extract of Matoa (Pometia pinnata) Leaves from Kudus, Central Java, Indonesia
Authors: Putri Adhina Choiri , Yuliana Tri Novia , Suzery Meiny , Aminin Agustina Lulustyaningati Nurul
Published: January 2024

Matoa (Pometia pinnata) is a plant used as a floral identity in Indonesia, especially in Papua. Local people use boiled water from matoa leaves, which is believed to treat hypertension. Matoa leaves are traditionally used as a therapeutic agent for burns and wounds in Indonesia. Phytochemical screening of matoa leaf extract contains secondary metabolite compounds, including flavonoids, steroids, tannins, and saponins. So far, many of these activities have been reported from the polyphenol group. This research aimed to identify the phytochemical composition of matoa leaves from Kudus in the ethanolic extract using LC-MS. The total phenolic content of ethanol extract using the Folin Ciocalteu method was 35.689 ± 0.726 mg GAE/g extract. The total flavonoid content of ethanol extract using the AlCl3 colorimetric method was 1.384 ± 0.012 mg QE/g extract. Twelve compounds could be identified in the ethanol extract of matoa leaves. The phenolic compounds were vanillin, p-hydroxybenzaldehyde, p-Coumaroyl glycolic acid, syringic acid, gallic acid, phenol, and vanillic acid. The flavonoid compounds were identified as epigallocatechin and apigenin -7-O-diglucuronide. The organic compound was identified as jasmonic acid. The aromatic compound was identified as benzene. Besides, tannin compounds were also identified. The major compounds in matoa leaves from Kudus, Central Java, are vanillin, phenol, and benzene.
Z działalności niemieckiego Sądu Specjalnego w Radomiu w latach 1939-1945
Authors: Wrzyszcz Andrzej
Published: January 2024

W okresie okupacji działały na ziemiach polskich różne sądy niemieckie. Na terenach wcielonych do III Rzeszy największe znaczenie miały sądy specjalne (Sondergerichte). Działalność tych sądów znalazła szerokie odbicie w polskiej literaturze historyczno-prawnej. Fundamentalne znaczenie mają  przede wszystkim prace Edmunda Zarzyckiego, Alfreda Koniecznego, Jana Waszczyńskiego, Stanisława Godlewskiego. Problematyka ta została także dostrzeżona w historiografii niemieckiej. Obok syntez zawartych w fundamentalnych dziełach poświęconych wymiarowi sprawiedliwości III Rzeszy pojawiaj się też szczegółowe rozprawy analityczne. Ostatnio opublikowana została praca doktorska Gerda Weckbeckera Zwischen Freispruch und Todesstrafe. Die Rechtsprechung der nationalsozialistischen Sondergerichte Frankfurt/Main und Bromberg.
Student teachers’ opportunities to learn through observation, own practice and feedback on the practice while in field practice placements: a graphical model approach
Authors: Nielsen Tine
Published: January 2024

Field practice placement is a crucial part of teacher education, as it affords a real-life context, where teacher and teacher-related skills can be enacted and trained. The present study examined the associations between student teacher opportunities to learn through observation, own practice and the receiving of feedback of said practice, while in field practice placements through a teacher education programme. Chain graph models were used to analyse data from 560 Danish student teachers who had just completed field practice at one of three levels. Results showed that opportunities to learn through observation of fellow students and other teachers was negatively associated with level of field practice, and thus was reported less and less the further along students were in the programme, while opportunities to learn through own practice was positively associated with level of field practice. Opportunities to learn through receiving feedback on own practice was associated with level of field practice only via opportunities to learn through own practice. Results did not reveal gender or age-wise inequity in the opportunities to learn afforded in the field practice. Teacher education programmes could benefit from placing additional focus on opportunities to learn through observation in the later field practice placements.
Unlocking the Potential of Garnet Ferrites: A Comprehensive Review on Properties, Preparation Methods, and Applications
Authors: Sharma Anjori , Dipesh
Published: January 2024

This review paper provides a comprehensive overview of the recent advances in garnet ferrites, a class of complex magnetic oxides with promising properties for various applications. The paper covers the crystal structure and different properties of garnet ferrites as well as their synthesis methods, including sol-gel auto-combustion, low-temperature liquid phase epitaxy, pulsed laser deposition, coprecipitation method, sol-gel, hydrothermal, ball billing method, and low-temperature solid-state reactions. The functional properties of garnet ferrites, such as permeability, hysteresis loop, loss mechanics, and saturation magnetization, are also discussed in detail, along with their potential applications in microwave devices, antennas, Faraday lasers, and cancer treatment. Finally, the challenges and future directions for the development of garnet ferrites are outlined, highlighting the need for further research to optimize their properties and improve their performance in real-world applications.
Emotional Distress Disparities Across Multiple Intersecting Social Positions: The Role of Bias-Based Bullying
Authors: Eisenberg Marla E. , Lawrence Samantha E. , Eadeh Hana-May , Suresh Malavika , Rider G. Nic , Gower Amy L.
Published: January 2024

OBJECTIVES

To apply an intersectional lens to disparities in emotional distress among youth, including multiple social positions and experiences with bias-based bullying.

METHODS

Data are from the 2019 Minnesota Student Survey (n = 80 456). Social positions (race and ethnicity, sexual orientation, gender) and 2 forms of bias-based bullying (racist, homophobic or transphobic) were entered into decision tree models for depression, anxiety, self-injury, suicidal ideation, and suicide attempts. Groups with the highest prevalence are described. Rates of emotional distress among youth with matching social positions but no bias-based bullying are described for comparison.

RESULTS

LGBQ identities (90%) and transgender, gender diverse, and questioning identities (54%) were common among the highest-prevalence groups for emotional distress, often concurrently; racial and ethnic identities rarely emerged. Bias-based bullying characterized 82% of the highest-prevalence groups. In comparable groups without bias-based bullying, emotional distress rates were 20% to 60% lower (average 38.8%).

CONCLUSIONS

Findings highlight bias-based bullying as an important point for the intervention and mitigation of mental health disparities, particularly among lesbian, gay, bisexual, transgender, gender-diverse, queer, and questioning adolescents. Results point to the importance of addressing bias-based bullying in schools and supporting lesbian, gay, bisexual, transgender, gender-diverse, queer, and questioning students at the systemic level as a way of preventing emotional distress.
Influencia da Qualidade do Sono na Qualidade de Vida no Trabalho de Policais Militares
Authors: De Oliveira Bruno Gonçalves , Dos Santos Bomfim Eliane , Ramon Brito Teixeira Jules , Narriman Silva de Oliveira Boery Rita , Nagib Boery Eduardo
Published: January 2024

Introdução: A profissão policial é considerada de alto risco e exige um vigor físico e mental do trabalhador diante do serviço realizado. De tal modo que uma boa qualidade do sono é importante, pois impacta diretamente em diversos aspectos na saúde desses trabalhadores. Ademais, a falta de uma boa qualidade do sono devido ao trabalho pode influenciar negativamente a qualidade de vida no trabalho.
Objetivo: Analisar a influência da qualidade do sono na qualidade de vida no trabalho de policiais militares.
Metodologia: Estudo quantitativo, correlacionalde corte transversal, realizado no primeiro semestre de 2019, com policiais de três municípios da Bahia, Brasil. Foram utilizados três instrumentos: sociodemográfico e características laborais; qualidade de vida de vida no trabalho; e qualidade do sono. Foi aplicado o teste do qui quadrado para as variáveis sociodemograficas e ocupacionais. Posteriormente, foi aplicado o teste de correlação de Spearman entre a qualidade do sono com as dimensões da qualidade de vida no trabalho.
Resultados: Evidenciou-se entre os 298 policiais que a mediana da idade foi de 40 anos e tempo de serviço ≤ 7 anos, observou-se também que os policiais com pior qualidade do sono apresentaram qualidade de vida no trabalho insatisfatória em todas as dimensões (biológica/fisiológica; psicológica/comportamental; sociológica/relacional; econômica/política, ambiental/organizacional).
Conclusão: Os policiais sofrem com a qualidade do sono e consequentemente influencia negativamente a qualidade de vida no trabalho. Assim, há uma necessidade de desenvolver ações no ambiente de trabalho que possam diminuir os afastamentos decorrentes dos problemas de saúde ocasionados pela qualidade do sono.
Relação Enfermeiro-Pessoa Afetada pela Tuberculose Fundamentada na Teoria do Alcance de Metas de Imogene King
Authors: Bringel Silva Ingrid Grangeiro , De Sales Janayle Kéllen Duarte , Silva Santos Sheron Maria , Da Silva Lúcia de Fátima , Pereira Borges José Wicto , Gomes Rocha Cavalcante Edilma
Published: January 2024

Introdução: As ações desenvolvidas na Atenção Primária à Saúde são um dos pontos fortes de combate à tuberculose. Nesse nível de atenção, o contato contínuo do enfermeiro por meio da consulta de enfermagem permite manter relação com a população adoecida. Diante da relação enfermeiro-pessoa cuidada para o estabelecimento do vínculo e adesão ao tratamento contra tuberculose, compreende-se a importância do referencial teórico de Imogene King para estruturar a interação enfermeiro-pessoa cuidada e oferecer uma dinâmica para esse processo.
Objetivo: Analisar a relação enfermeiro-pessoa afetada pela tuberculose fundamentada na Teoria do Alcance de Metas de Imogene King.
Método: Estudo descritivo com abordagem qualitativa, com 14 enfermeiros da APS, selecionadas por conveniência. A coleta de dados ocorreu de agosto a novembro de 2018, por meio de entrevista semiestruturada, elaborada com base no Registro Meta-Orientado de Enfermagem de Imogene King. Os dados foram analisados de forme qualitativa pelo Software IRAMUTEQ. A pesquisa foi aprovada pelo Comitê de Ética.
Resultados: Após a análise, emergiram quatro classes: 1) relação estabelecida com base no acolhimento; 2) relação enfermeiro-pessoa com tuberculose e o apoio de outros profissionais e familiares; 3) relação estabelecida com vistas ao cumprimento do tratamento; e 4) relação estabelecida para enfrentamento do preconceito diante da tuberculose.
Conclusão: O acolhimento, a família e o vínculo entre profissional, paciente e equipe da Atenção Primária à Saúde fortalecem o enfrentamento da doença e reforçam a adesão ao tratamento medicamentoso.
Digital image processing applications in agriculture with a machine learning approach
Authors: Yasmin Suraiya , Billah Masum
Published: January 2024

Abstract. Digital image processing involves the manipulation of images by digital means, and its use has been increasing exponentially in recent decades. It is applied in a diverse range of fields including medicine, remote sensing, robotic vision, and audiovisual processing. Image processing technologies are widely used as a proficient tool in the agriculture sector. The combination of digital image processing and machine learning not only provides new insights into crop health and environmental circumstances, but also helps farmers reach timely and precise decisions. Using machine learning methods, this study examines digital image processing applications in agriculture, focusing on plant disease identification, fruit quality evaluation, weed detection, yield mapping, and robotic harvesting, to other issues. In essence, this study integrates existing knowledge at the interface of digital image processing, machine learning, and agriculture, providing insights into a promising and growing topic with significant implications for sustainable and resilient food production.
Relationship between seed density, some characteristics of the sowing apparatus and the amount of seed sown
Authors: Kehayov D. , Zahariev I. , Bojkov I.
Published: January 2024

Abstract. Grain production provides significant resources for the food industry and animal husbandry. One of the most important moments in the cultivation of cereals is the planting of seeds in the soil. The sowing process is influenced by many factors. This study examines the impact of two such factors: seed density and the length of the sowing apparatus. These factors affect the quantity of seeds sown. Factor analysis demonstrated that changes in seed density exert a more substantial influence on seed quantity alterations. A functional relationship has been determined between the amount of seed sown, the length of the sowing apparatus in the seed box and the density of the crop used.
Quality assessment of commercial Bulgarian brined cheese, purchased in the commercial network
Authors: Buhalova D. , Nikolova Kr. , Milkova-Tomova Il. , Alexieva I. , Gerasimova A. , Gentscheva G. , Dimitrova P.
Published: January 2024

Abstract. Three types of Bulgarian brined cow cheese, produced according to the Bulgarian State Standard 15:2010 (BDS), and five types, according to individual cheese makers' firm technological production instruction (TPI), have been studied. Salt content, dry matter, titratable acidity, and fat content have been determined. Using the gas chromatographic method, we have identified the fatty acid composition according to ISO 12966-1. A descriptive sensory profiling test have been conducted for each sample to determine the studied parameters such as appearance, taste, smell, and consistency. Some of the TPI samples have been characterized by a high concentration of salt (% in the total mass), a low percentage of dry matter, and high water content. Only one of the examined samples, according to TPI, met the criteria for acidity according to BDS. The gas chromatographic analysis showed an increased content of palmitic acid in one of the TPI samples. For the examined samples of white brine cow cheese, labeled as produced according to the BDS standard, the obtained results were close to or fully compliant with the standard, with the exception of the titratable acidity in one of the samples. For the samples produced by TPI, the obtained results for these samples are not inferior to those produced by BDS.
Środowisko rodzinne a nadwaga i otyłość u dzieci
Authors:   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rzeszów, Polska, Baran Joanna , Chlebek Wiktoria ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rzeszów, Polska, Leszczak Justyna ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rzeszów, Polska, Baran Rafał ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rzeszów, Polska, Pop Teresa ,   Instytut Nauk o Zdrowiu, Kolegium Nauk Medycznych, Uniwersytet Rzeszowski, Rzeszów, Polska
Published: January 2024

Introduction: The aim of the study was to investigate the influence of such factors as: age, sex, place of residence, number of people in a household, education and professional status of parents on the prevalence of obesity and overweight in children. Material and method: The study group consisted of 83 children, including: 42 boys and 41 girls, aged 12–15 years. The research used: a questionnaire, measurement of height and weight as well as percentile grids developed on the basis of the OLA OLAF project. The obtained results were statistically processed. Results and conclusions: Gender, age, number of household members and mother’s education did not affect the prevalence of obesity and overweight in the studied children. The place of residence, education of the father and the professional status of both parents are factors that differentiate the prevalence of obesity and overweight in the studied population.
Syntetyczna ocena poziomu zagrożenia czynnikami ryzyka, ocena rozwoju fizycznego i psychomotorycznego u niemowląt diagnozowanych metodą Vojty
Authors:   Kolegium Nauk Medycznych UR, Bejster Anna , Przysada Grzegorz ,   Kolegium Nauk Medycznych UR
Published: January 2024

Introduction: Aims of the study: 1. The aim of the study was to assess the level of risk with risk factors measured by the synthetic diagnostic function of Z PZCPN in infants from the study group (GB) diagnosed with the Vojta method, compared to the control group (CG). 2. Assessment of the strength of the influence of individual diagnostic features on the level of Z PZCPN . 3. Synthetic evaluation of the physical development of Z PRF and psychomotor development of Z PPRM . Material and methods: The study group consisted of 104 infants with a burdened pregnancy-perinatal (GB) history, the control group consisted of 50 healthy children (CG). The method of A. Krefft was used to evaluate the function of Z PZCPN . Psychomotor development was characterized by the tests of the Munich Developmental Diagnostics (MFDD) in a synthetic way by means of the Z PRPM function, physical development – by the Z PRF function. Study results: Significantly higher level of risk of Z PZCPN was noted in children with GB compared to CG (p ≤ 0.001) and in premature babies and infants with moderately severe disorders (p ≤ 0.001p ≤ 0.01). A significantly lower level of psychomotor development was also noted in these subgroups. Neonatal immaturity, smaller body dimensions, low Apgar fitness, complications of the neonatal period had the strongest influence on the level of risk. Conclusions: In the group of examined children (GB), a significantly higher level of risk with risk factors measured by the function of Z PZCPN and a lower level of physical development were found, compared to the control group of healthy children (p <0.001). In infants at risk with a higher degree of central nervous coordination disorders and shorter duration of pregnancy, a higher level of risk and a lower level of psychomotor development have been demonstrated. The presence of risk factors, disorders of central nervous coordination and delays in psychomotor development requires the implementation of therapeutic measures.
Ocena równowagi u osób między 50. a 60. rokiem życia
Authors:   Uniwersytet Rzeszowski, Rzeszów, Polska, Pop Teresa , Baran Joanna ,   Uniwersytet Rzeszowski, Rzeszów, Polska, Jasic Zbigniew ,   Uniwersytet Rzeszowski, Rzeszów, Polska
Published: January 2024

Introduction: The aim of the study was to assess the impact of selected factors on the static and dynamic balance of people between 50 and 60 years of age. Material and methods: The study included 100 people. Half of those who undertook work requiring movement, did not report dizziness and mostly systematically undertook physical activity. The other half are people with osteoarthritis of the spine and/or joints of the lower limbs and/or foot defects, a large part suffered dizziness, the majority were passive in terms of physical activity, and the working mode monotype was more frequent. Functional tests were used to assess the balance. Dynamic balance was tested using the Up and Go and Tandem walk test, and the static balance was assessed using the One leg standing test and Tandem pivot test. Results: The results presented in the work indicate that the factors taken into account influence the type of balance being studied. This is evidenced by the various results obtained in the study using four functional tests. In each test used in research, there were results at different levels of statistical significance. Conclusions: Unchangeable and monotype work affects the quality of the balance of people over 50 years of age. Rarely undertaken physical activity affects body control, and a small stimulation of the deep sensory senses significantly weakens it. The presence of osteoarthritis in the joints and/or foot defects is an individualized phenomenon, but they are translated into the level of the static and dynamic balance control system. An important role in disturbances in the balance of the body are dizziness. It allowed to formulate the thesis that the dynamic and static balance deteriorate in the process of involution, coexisting with the examined parameters.
Peculiarities of treatment of patients with comorbid pathology: chronic pancreatitis and hypothyroidism, taking into account SEPP1 gene polymorphism (RS7579)
Authors: Ratsa Veronika , Fediv Olexandr , Sydorchuk Larisa
Published: January 2024

Optimization of therapeutic regimens during the treatment of the polymorbid course of chronic pancreatitis combined with hypothyroidism is an important task of modern science.
Aim: to treat patients with comorbid pathology: chronic pancreatitis and hypothyroidism, taking into account the polymorphism of the SEPP1 gene (RS7579)
Materials and methods. During the research, we examined 128 people. Patients were divided into 3 groups. The first group included 48 patients with chronic pancreatitis, the second - 50 patients with chronic pancreatitis in combination with hypothyroidism, and the third - 30 practically healthy people.
Results. Symptoms of maldigestion decreased in 72 % of the examined patients. Signs of nutritional deficiency have significantly decreased, and general well-being has improved. Multicomponent therapy also affected mood, sleep, and reduced irritability and symptoms of depression and anxiety disorders. A multisystemic polysyndromic approach to treatment led to improvements in both pancreatic and thyroid function. The effectiveness of the treatment strategy for patients with chronic pancreatitis was dependent on individual characteristics, such as the severity of chronic pancreatitis, the presence of primary hypothyroidism, the degree of selenium deficiency and concomitant symptoms, taking into account polymorphic variants of the SEPP1 (rs7579) gene. Selenoid deficiency decreased, especially in the group with a combination of chronic pancreatitis and hypothyroidism. The improvement in thyroid hormone activity included a 40.46 % decrease in blood TSH and a 2.5-fold increase in free T4.
Conclusions. The program of complex therapy led to the normalization of the condition of patients with the G-allele genotype of the SEPP1 gene (rs7579), as evidenced by significant improvements in most of the analyzed indicators. The concentration of fecal elastase 1 and blood selenoprotein P significantly increased, and the level of serum pancreatic α-amylase significantly decreased in carriers of the AA genotype. Under the influence of therapy, there were also changes in the hormonal activity of the thyroid gland, a decrease in the concentration of total metabolites of NO, and an improvement in the health indicators of the cardiovascular system. However, for patients with the AA genotype of the SEPP1 (rs7579) gene, continuation of therapy remains important to achieve an optimal condition, in particular, to manage cholesterol levels and other cardiovascular risk factors
Cytotoxicity and antitumor activity of sesquiterpene lactones. Structure, activity
Authors: Maslova Olga , Iskakova Zhanar , Doskaliyev Aidos , Adekenov Sergazy
Published: January 2024

The article discusses the results of 19 samples screening of sesquiterpene γ-lactones argolide, grosheimin, estafiatin, and their derivatives for cytotoxicity and antitumor activity. The research results indicate significant cytotoxicity and selectivity of the action of sesquiterpene γ-lactones and their derivatives against most tumor cell lines.
Aim. The purpose of this study is to study the cytotoxicity and antitumor activity of the sesquiterpene γ-lactones argolide, grosheimin, estafiatin and their chemically modified derivatives, as practically renewable materials.
Methods. The cytotoxicity of the compounds was determined using vero cells, THP-1, Pliss lymphosarcoma cell lines, Walker carcinosarcoma, sarcoma 45, sarcoma-180, alveolar liver cancer PC-1, P-388 leukemia, L-1210 leukemia, and resistant to 5-fluorouracil sarcoma 45.
The antitumor activity of the samples was studied in in vivo experiments on white outbred rats with transplanted tumor strains and was assessed by inhibition of tumor growth and the magnitude of the increase in average life expectancy.
Statistical processing of the results was carried out using the program “GraphPad Prism v. 6.0" (GraphPad Software Inc., USA).
Conclusion. When determining cytotoxicity in in vitro samples of the sesquiterpene γ-lactones argolide, grosheimin, and estafiatin showed selectivity of their action on cells of 8 tumor lines, on cells of human acute monocytic leukemia THP-1 and in relation to the larvae of sea crustaceans Artemia salina (Leach).
Samples of argolide, 8-acetylgrosheimin, 13-morpholinogrosheimin, 3-keto-4-methylene-cis-guaianolide, 3α-acetoxyisozaluzanin C, and 10α(14)-epoxy-1,5,7α,4,6β(H)-guai-11(13)-en-4(3),6(12)-diolide in experiments in vivo possessed high antitumor activity against transplantable tumor strains of Pliss lymphosarcoma, Walker carcinosarcoma, sarcoma 45, sarcoma 37, sarcoma 180, alveolar liver cancer PC-1, leukemia P-388 and L-1210, resistant to 5-fluorouracil sarcoma 45
Features of the legal status of political parties as legal entities: comparative-legal characteristics
Authors: Piddubna Victoriia
Published: January 2024

In the article, the author examines political parties as subjects of civil relations. The characteristics of political parties as legal entities are analyzed: organizational unity, which is expressed in the fact that parties, as organizations, have a certain structure and a system of bodies; the sign of separate property of political parties has a certain specificity, with peculiarities in the ways of acquiring ownership rights over the property of political parties. Political parties, as legal entities, bear civil liability, and they can independently appear in court as defendants.
The author also examines the doctrine and legislation of Western countries regarding the concept, creation, and activities of political parties in Germany, the United States, Great Britain, and Serbia. The concept of a political party in Western countries is considered, with a political party in Serbia, understood as a voluntary association of citizens, created with the aim of achieving political goals through the democratic formation of the political will of citizens and participation in elections. A political party in Serbia is granted the status of a legal entity from the date of its entry into the register of political parties.
A distinctive feature of political parties in Germany is their ambiguous legal status. By their legal nature, they are private organizations, created in accordance with the norms of private law; however, they also possess a public character due to certain constitutional privileges, granted to them.
The article explores the issue of the legal nature of political parties in Ukraine and the features that distinguish political parties from other public associations. The author examines the issue of the legal personality of political parties and points out that they possess two components - social and political.
Furthermore, the article analyzes the criteria for categorizing legal entities as either private or public law entities in the law of Ukraine and in the law of France. In French law, such criteria include the following: the establishment of a legal entity originating from public or private initiative, the rules governing its creation, operation, and oversight by public authorities, the method of financing (public subsidies or mandatory payments), and the presence of public authorities
Comparative analysis of the functions of judicial and notary bodies
Authors: Kyianytsia Lina
Published: January 2024

A comparative analysis of the functions of judicial bodies and notary bodies was carried out through a constructive analysis of norms of civil legislation, unexplored aspects of these functions were identified. Both general theoretical and special methods became the methodological basis of the research. The method of comparative analysis made it possible to determine the common and distinctive features of the functions of the court and the notary in civil legal relations. The dialectical method made it possible to find out which of the functions can be transferred from the competence of one body to another. It has been clarified what role both courts and notaries play in regulating civil legal relations. Forms of protection of civil rights and interests by both notary and judicial bodies were studied. It has been established that the implementation of an executive inscription on a debt document by a notary is not the only form of protection of civil rights and interests of individuals and legal entities by a notary. It has been determined that the role of the court in civil legal relations is not limited to the protection of the violated right or interest, in particular, when deciding the issue of limiting the civil capacity of a person or recognizing him/her as incapable, establishing guardianship and care by the court. It is proposed to introduce a new institution of civil law regarding the exercise by an individual of an order for guardianship or care in the event of his/her future incapacity or limitation in legal capacity, as well as to expand the limits of the exercise of civil rights by individuals and to grant such powers to the notary through the certification of a certain type of contract or order, in order to reduce the burden to the judicial system in cases where there is no legal dispute. It has been established that both judicial bodies and notary bodies have a common subject of regulation in civil legal relations, while it is noted that judicial bodies have an influence on the notary in the context of the possibility of invalidating transactions that were notarized
Mathematical modelling of applanation loading of the eyeball with account for the nonlinearity of the cornea
Authors:   Institute of Mechanics, Moscow State Lomonosov University, Moiseeva Irina , Stein Alexander
Published: January 2024

Mathematical modelling of the deformation of the eyeball loaded by a heavy stamp with a flat base is performed, which corresponds to Maklakoff tonometry. The modelling is carried out within the framework of the general approach developed by the authors, which represents the eyeball as a set of a deformable two-dimensional surface (cornea) and a zero-dimensional element that responds with a change in volume to changes in intraocular pressure (scleral region). The behavior of both components is assumed to be elastic: linear for the scleral region and non-linear for the cornea. For the latter, an exponential model developed by the authors was used, in which the nonlinearity of the elastic properties of the cornea is characterized by a single parameter. The calculations were carried out in the range of values of the nonlinearity parameter, estimated on the basis of data on tension of an isolated cornea by pressure. It is shown that taking into account the nonlinearity leads to an increase in the difference between the pressures in a loaded and unloaded eye (tonometric difference) and an increase in the slope of the dependence of tonometric pressure on the tonometer weight (pressure difference coefficient) during elastotonometry. The calculated corrections make it possible to propose refinements for the procedure of processing clinical measurement data. However, such conclusions should be considered as preliminary: there are no final estimates of the nonlinearity parameter for living eyes and they should be obtained as a result of comparing the calculation results with clinical studies. In particular, it is necessary to find out to what extent the values of this parameter are individual and may differ for different eyes.
Distribution of blood components in the Poiseuille flow
Authors:   G.A. Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, Fedoseev Victor
Published: January 2024

he thermodynamic approach is used to describe the stationary distributions of blood components in a cylindrical Poiseuille flow. Based on it, a method is described for numerical modelling of the distribution of blood components over the blood vessel cross section. Dispersed phases are represented by a combination of cellular components (red blood cells, white blood cells, etc.), blood plasma is considered as a low molecular weight dispersion medium. The distributions are obtained on the basis of the invariance condition of mechanochemical potentials (the sum of the chemical potential and mechanical energy) of the components, which is fulfilled at stationary equilibrium in stationary external fields of different nature. The calculation is reduced to a numerical search for a solution to a system of transcendental equations corresponding to the continuity of the medium. This system has a unique solution that describes the consistent distributions of all the components of a multiphase flow over the cross-section. It is shown that at the Poiseuille flow, the distributions of the individual dispersed phases can have up to three symmetrical extrema, the position of which is determined by the flow conditions (shear rate, vessel diameter, blood composition). As a demonstration of the model’s capabilities, the distribution of blood components (erythrocytes, platelets, lymphocytes) for vessels with a diameter of 0.1 to 5 mm at shear rates from 1 to 100 s–1 is given. It is shown that there is a very complex relationship between flow parameters (shear rate, diameter of a blood vessel) and blood composition. Unlike most hydrodynamic models of two-phase flows, the thermodynamic approach allows one to consider the distributions of an arbitrary set of dispersed and low molecular weight blood components, including foreign ones.
Changes in common carotid artery elasticity in solid organ recipients
Authors: Shevchenko A. O. , Tyunyaeva I. Yu. , Lysenko M. M. , Koloskova N. N. , Saydulaev D. A. , Zubenko S. I. , Vakurova E. A. , Sharapchenko S. O.
Published: January 2024

Background. Cardiovascular diseases are very common among solid organ recipients. They are associated with worsening transplant outcomes. Arterial vascular wall elasticity is an important prognostic indicator and a risk marker for cardiovascular events. Noninvasive measurement of common carotid artery (CCA) elasticity may be useful in assessing cardiovascular risk in solid organ recipients.

Objective: To conduct a comparative analysis of indicators of CCA elasticity in solid organ recipients and to study their relationship with factors that potentially have a negative impact on the risk of adverse events.

Materials and methods. The study included 154 patients aged 10 to 75 years, including heart (n = 77), liver (n = 9), and kidney (n = 35) recipients, as well as 33 patients with end-stage heart failure waitlisted for heart transplantation (HT). In all participants, carotid artery ultrasound was performed, pulse wave velocity was measured, and CCA elasticity was calculated.

Results. CCA elasticity was found to be strongly inversely correlated with age, body mass index, systolic blood pressure, renal tubular filtration rate, CCA intima media thickness, and aortic pulse wave velocity. In heart recipients, CCA elasticity was significantly lower than in liver and kidney recipients (p = 0,002) and it inversely correlated with the length of time elapsed after transplantation, which is probably associated with cardiac denervation.

Conclusion. CCA elasticity calculated via noninvasive ultrasound reflects the degree of adverse effects of pathological factors on the main arteries in solid organ recipients.
Treatment of vascular complications following orthotopic liver transplantation. The experience of a regional cente
Authors: Korobka V. L. , Kostrykin M. Yu. , Malevanny M. V. , Kotov O. V. , Korobka R. V. , Pak E. S. , Khoronko Yu. V. , Sapronova N.  G. , Sukhanov I. A. , Khoronko R. Yu.
Published: January 2024

Objective: vascular complications (VCs) following liver transplantation (LT) can pose a significant threat to the recipient’s life – as the risk of graft loss increases significantly when blood flow in the graft is impaired. Diagnosis and early treatment of VCs seems to be a pressing issue in transplantology. The aim of this study is to evaluate the incidence, treatment and outcome of VCs in patients after orthotopic LT at the Center for Surgery and Donor Coordination, Rostov Regional Clinical Hospital.

Materials and methods. Between July 2015 and April 2023, 100 orthotopic LTs were performed. VCs were retrospectively identified and analyzed.

Results. The overall incidence of VCs was 24% (n = 24): hepatic artery stenosis, 5% (n = 5); intra-abdominal bleeding, 6% (n = 6); hepatic artery dissection, 2% (n = 2); intrahepatic venous thrombosis Budd–Chiari syndrome), 2% (n = 2); portal vein thrombosis, 1% (n = 1); inferior vena cava thrombosis/iliofemoral deep vein thrombosis, 2% (n = 2); inferior vena cava stenosis, 1% (n = 1); hepatic vein stenosis, 1% (n = 1); recurrent hepatic artery stenosis/thrombosis, 2% (n = 2); mesenteric vein thrombosis, 2% (n = 2).

Conclusion. Most VCs following orthotopic LT occur in the early postoperative period and can lead to a high risk of graft dysfunction and patient death. Early recognition, diagnosis, and treatment of post-LT complications are critical to successful short- and long-term graft function and patient survival, even in patients with asymptomatic complications. Treatment options typically include surgical revascularization, percutaneous thrombolysis, percutaneous angioplasty, retransplantation, or, less commonly, a conservative approach.
Celso Furtado e o pensamento econômico brasileiro
Authors: MANTEGA GUIDO
Published: January 2024

RESUMO As obras de Celso Furtado marcam tanto o surgimento quanto a consolidação do pensamento econômico brasileiro. Suas principais obras (como Formação Econômica do Brasil e Desenvolvimento e Subdesenvolvimento) estabeleceram a base de referência para o debate econômico ocorrido nos últimos trinta anos no Brasil. A teoria do subdesenvolvimento, elaborada por Celso Furtado, forneceu a base teórica do desenvolvimento, a doutrina que norteou as políticas econômicas de vários governos latino-americanos e afirmou o estabelecimento da industrialização no Brasil. Este artigo busca recompor os passos para a constituição da teoria do subdesenvolvimento, explicitando as principais questões teóricas sobre esse problema e seus resultados práticos.
Análise gravimétrica por meio de smartphones e aprimoramentos nas equações do experimento do pêndulo simples como subterfúgio para o ensino de Física Clássica
Authors: Rossini Marcos Roberto , Alves Marcio José , Camargo Filho Paulo Sérgio de , Piccinato Marilene Turini , Amorin Luís Henrique Cardozo
Published: January 2024

A Gravimetria contemporânea vale-se de gravímetros para encontrar o módulo da aceleração gravitacional (g) de forma pontual na superfície terrestre. Esse trabalho considerou a pertinência da determinação de g no laboratório didático por intermédio do pêndulo, fazendo atenciosa análise dos fenômenos que afetam o dispositivo em oscilação, trazendo contribuições para o ensino da Física Clássica. A primeira, embora modesta, é eficaz, e propõe medir o período de oscilação empregando dois smartphones. A segunda, uma análise teórica acerca do efeito da amplitude angular correlacionada ao arrasto, sobre o período de oscilação do pêndulo. A terceira, refere-se à validação de duas equações que fornecem o valor de g em função da latitude e da altitude, com os dados gravimétricos disponíveis no site do IBGE. No campus Londrina da UTFPR, realizaram-se ensaios independentes, permitindo que se obtivesse o valor g U T F P R − L d = ( 9,7873 ± 0,0012 ) m ⋅ s − 2. Para a validação da metodologia e verificação da acuracidade, as duas equações que fornecem g em função da altitude e da latitude foram confrontadas com dados gravimétricos para definir qual seria mais adequada para gerar o valor de referência. Assim feito, verificou-se que o valor obtido experimentalmente divergia em 0,001 m ⋅ s − 2 (0,01%).
Relação dos níveis de hemoglobina com desfechos em transplante renal de doador falecido: um estudo de coorte retrospectivo
Authors: Silva Beatriz Moreira , Macedo Flavia Hosana , Hayano Enzo Eiji Miyasato , Germano Suzeli , Ribeiro Isabella Ferreira , Franco Carolina Azze , Requião Lucio , Medina-Pestana José , Goes Miguel Angelo
Published: January 2024

RESUMO Introdução: A anemia é frequente em pacientes submetidos à terapia substitutiva para insuficiência renal. A anemia nos períodos pré e pós-transplante pode estar relacionada aos desfechos do transplante renal. Portanto, o presente estudo buscou avaliar a relação entre anemia, função retardada do enxerto (FRE), disfunção crônica do enxerto renal (DCE) e óbito por qualquer causa após transplante renal de doador falecido. Métodos: Este foi um estudo retrospectivo com 206 pacientes transplantados renais de doadores falecidos. Analisamos dados demográficos de doadores falecidos e pacientes transplantados renais. Além disso, comparamos parâmetros bioquímicos, status de anemia e medicamentos entre os grupos FRE e não-FRE. Posteriormente, realizamos uma análise multivariada. Também avaliamos desfechos, como DCE em um ano e óbito em dez anos. Resultados: Observamos menor frequência de concentração de hemoglobina (Hb) pré-transplante, mas maior frequência de creatinina sérica do doador e transfusão de hemácias no período de uma semana após o transplante no grupo FRE. Além disso, houve associação independente entre a concentração de Hb antes do transplante e a FRE [OR 0,252; IC 95%: 0,159–0,401; p < 0,001]. Houve também associação entre a concentração de Hb após seis meses de transplante renal e ambos, DCE [OR 0,798; IC95%: 0,687–0,926; p = 0,003] e óbito por qualquer causa. Conclusão: Encontrou-se uma associação entre anemia pré-transplante e FRE e entre anemia seis meses após o transplante e ambos, DCE e óbito por qualquer causa. Assim, a anemia antes ou após o transplante afeta os desfechos de pacientes que foram submetidos a transplante renal de doador falecido.
A morte e o morrer na infância de imigrantes letões: representações na revista Rihta Rasa (1925-1926)
Authors: Osis Sibila Lilian , Gondra José Gonçalves
Published: January 2024

Resumo A formação da colônia de imigrantes letões em Varpa, interior de São Paulo, iniciou em 1922. Devido às precárias condições sanitárias e de alimentação, mortes começaram a ocorrer, em especial de crianças de até 14 anos. O objetivo foi analisar textos sobre a finitude da vida, da revista Rihta Rasa, em suas publicações de 1925 e 1926. Foram analisados cinco contos e um poema que remetiam ao processo de saúde-doença-morte. Observou-se que o material deu centralidade às crianças, condição que direcionou condutas e crenças dos personagens ficcionalizados. A prática religiosa, articulada à predominância das crenças do protestantismo batista, funcionou como elo entre os membros da comunidade, o que se expressou também em suas representações da infância e da finitude. A presença regular de tais recursos sinalizou a frequência do óbito de crianças e atualizou o emprego da retórica cristã natureza-eternidade, como forma de educar sobre as perdas, inclusive as precoces.
Regeneration of roots and shoots as a propagation strategy in Eugenia candolleana DC. (Myrtaceae) seeds
Authors: Alonso Camila Rivero , Ribeiro Maiara Iadwizak , Guardia Marina Crestana , Barbedo Claudio José
Published: January 2024

Abstract: Seeds of the genus Eugenia have high regenerative capacity, producing roots and shoots from seeds with reduced cotyledon matter. In addition, seeds of this genus regenerate new roots and shoots when the first roots and shoots are eliminated, and this characteristic is maintained even when the seed reserves are reduced by up to half. The aim of this study was to analyze the limits of new root and shoot regenerative capacity in whole and fractionated Eugenia candolleana seeds at different maturity stages. The regenerative capacity of seeds stored for six months was also evaluated. The seeds were sown; and when the first roots and shoots were produced, they were eliminated, simulating herbivory conditions. The results showed that the seed not only has high regenerative capacity at different maturity stages, but also that it maintains root regeneration when the seed is reduced by half, even after the storage period. Such information may indicate that seeds of the Eugenia genus can await the next crop season by regenerating several times as a way to withstand or tolerate predation. This ability can be understood as a propagation strategy of the species.
Machine learning in the identification of native species from seed image analysis
Authors: Felix Francival Cardoso , Kratz Dagma , Ribeiro Richardson , Nogueira Antônio Carlos
Published: January 2024

Abstract: The identification of seeds from native species is a complex assessment due to the high Brazilian biodiversity and varied characteristics between species. The objective was to apply different machine learning classifiers associated with image analysis to identify seeds of forest species. In total, 155 native species belonging to 42 botanical families were analyzed. In addition, to determine the appropriate machine learning classifier, five supervised learning classification techniques were implemented: decision trees (DT), artificial neural networks (ANN), k-nearest neighbors (k-NN), Naive-Bayes classifier (NBC) and support vector machine (SVM), which had their performance evaluated. For modeling, 66% of the seeds’ morphobiometric data were used to train the classifiers, while 34% were reserved for validation. The classifiers are promising tools for identifying species from seed images. The decision tree (DT) classifier showed greater accuracy for correct species identification (82.8%), followed by ANN (81.7%), k-NN (81.7%), NBC (81.1%) and SVM (78.7%). Therefore, it is possible to identify seeds of native species from images and machine learning with a satisfactory accuracy rate. Finally, the decision tree classifier is recommended.
Post-COVID-19 functional capacity assessed with ring and walk tests: cross-sectional study
Authors: Tozato Claudia , Molinari Camila Vitelli , Ferreira Bruno Fernandes Costa , Xavier Vivian Bertoni , Alves Vera Lúcia dos Santos
Published: January 2024

Abstract Introduction COVID-19 can cause persistent symptoms even in mild cases, such as fatigue and dyspnea, which can reduce functional capacity and make it difficult to perform activities of daily living. Objective To compare functional capacity using the pegboard and ring test and the six-minute walk test responses in post-COVID-19 patients according to the ventilatory support used. Methods Cross-sectional study including 40 adults of both sexes after SARS-CoV2 infection between June 2020 and June 2021, with assessment of functional capacity using the pegboard and ring test (upper limbs) and the six-minute walk (lower limbs). Those who reported comprehension deficit or neuromuscular disease were excluded. All participants were evaluated between 15 and 90 days after the onset of symptoms, diagnosed by nasal swab and classified according to the ventilatory support used during the infection. Results The mean age of the participants (n = 40) was 54.30 (±12.76) years, with BMI 28.39 (±4.70) kg/m2 and pulmonary involvement in 51.49 (±17.47)%. A total of 37 participants were hospitalized with a stay of 14.33 (±15.44) days, and 30% were previously immunized, while 7.5% reached the predicted distance covered. The average achieved was 46.44% (398.63 ± 130.58 m) in the distance covered and 39.31% (237.58 ± 85.51) in the movement of rings. Participants who had invasive mechanical ventilation (n = 10) had the worst functional capacity in both tests 265.85 ± 125.11 m and 181.00 ± 90.03 rings, compared to 472.94 ± 88.02 m and 273.25 ± 66.09 rings in non-invasive ventilation (n = 8), 410.32 ± 90.39 m and 257.68 ± 62.84 rings in oxygen therapy (n = 19), 569.00 ± 79.50 m and 203.00 ± 169.00 rings when there was no hospitalization (n = 3). Conclusion Participants who required invasive mechanical ventilation had worse functional capacity, 46% of what was expected in the walk test and 39% of what was expected in the pegboard and ring test.