bluuebunny/crossref_metadata_2025 huggingface dataset:
Супрамолекулярный комплекс на основе производных 3-гидроксипиридина предотвращает остеопороз, вызванный дефицитом эстрогенов, ингибируя окислительный стресс
Authors: Трунов К. С. , Даниленко А. П. , Гудырев О. С. , Даниленко Людмила Михайловна , Покровский М. В. , Скачилова С. Я. , Чередниченко А. А. , Романенко Ю. В. , Щербинина А. А. , Коклин И. С. , Должиков А. А. , Боева Е. А.
Published: March 2023

Остеопороз представляет собой дисбаланс между формированием кости и ее резорбцией. Активные формы кислорода могут снижать продукцию NO эндотелием и ингибировать дифференцировку и пролиферацию остеобластов, усиливая дифференцировку остеокластов. В настоящее время не существует безопасных лекарственных средств для профилактики и лечения остеопороза, вызванного овариэктомией. Потенциальными фармакологическими веществами, способными снижать или предупреждать развитие остеопороза, являются производные 3-гидроксипиридина. Исследование остеопротекторных эффектов производных 3-гидроксипиридина проведено на 60 крысах-самках линии Вистар с использованием модели гипоэстроген-индуцированного остеопороза. Оценку остеопоретического действия проводили на основе рентгенологического анализа показателей плотности костной ткани, микроциркуляции с использованием лазерной допплеровской флоуметрии, расчета коэффициента эндотелиальной дисфункции, биохимических и гистоморфологических проб. Пероральное введение супрамолекулярного комплекса на основе производных 3-гидроксипиридина в дозе 50 мг/кг в течение 56 дней на модели гипоэстроген-индуцированного остеопороза приводит к повышению плотности костной ткани на 12,5 % (p < 0,001), увеличению уровня микроциркуляции на 39,6 % (p < 0,001), снижению коэффициента эндотелиальной дисфункции на 49,7 % (p < 0,001) и увеличению толщины костных трабекул на 19,1 % (p < 0,001) в сравнении с группой контроля. Снижение среднего значения показателей малонового диальдегида в экспериментальной группе с супрамолекулярным комплексом на основе производных 3-гидроксипиридина указывает на снижение активности остеокластов. Значительное повышение активности супероксиддисмутазы и глутатионпероксидазы на фоне введения изучаемого комплекса подчеркивает снижение окислительного стресса.
Developing media of virtual laboratory of science: To support as a pioneer of cyber-university
Authors: Yuliastrin Adisti , Vebrianto Rian , Berlian Mery , Thahir Musa
Published: March 2023

The Open University is a university that has been around for a long time, so that it is able to develop a learning process that demands the development of science and technology, both online and offline independently. Therefore, this study aims to describe and analyze the process and results of the development of a virtual science laboratory to support UT’s role as a pioneer of cyber-university in Indonesia. This research is a development-research that uses the ADDIE model. The instruments used were validation sheets filled in by 64 validators, practicality sheets and effectiveness sheets filled out by 237 respondents. The data analysis used to answer the research objectives was descriptive and inferential statistical tests using the IBM SPSS 23.00 program. The results showed that product development in the form of textbooks based on the virtual laboratory of science met the valid, practical and effective criteria for use in the process learning. The results of this study have implications for stakeholders and teachers to be able to implement this media in a more appropriate and interesting learning process and can be a source of inspiration for conducting current research.
Digital ethics in higher education: Modernizing moral values for effective communication in cyberspace
Authors: Zvereva Ekaterina
Published: March 2023

The digitalization of education is critical to transforming the education system in the face of the challenges of the post-pandemic technologized world. This research aims to determine the content of digital ethics and its role as a tool of effective communication in the cyberspace of each college, suitable for the practical solution of the assigned educational tasks. The data come from a questionnaire of 150 students and 60 faculty members in bachelor's and master's degree programs, conducted in April-May 2021 as part of a distance learning program. In addition, 30 administrators and 20 graduates were interviewed. The research results show that traditional moral values are undergoing significant change and must be modernized and codified. Relationships in the digital environment should be based on moral norms: duty, the self-discipline of the actors involved, mutual responsibility, and respect. The moral qualities displayed by individuals in the digital environment using digital technologies are the leading indicators of their professional suitability. The article mentions the main problems faced by the actors: digital literacy, personal image, place of implementation of pedagogical interaction, and rules of remote dialog. The study will contribute to further analysis and evaluation of the adequacy of specific measures taken by higher education institutions to develop and implement programs for ethical modernization of the educational process within the tasks of state educational reforms.
Independent Learning-Independent Campus: From the Perspective of Justice and Utilitarian Theories
Authors: . Suratman , Salamah Umi , Amini Sulaisyah , Navisa Fitria Dewi
Published: March 2023

The Regulation of the Minister of Education and Culture Number 3 of 2020 implies that learning experience should be able to build characters of graduates in both hard skills and soft skills as expected by learners, the needs of the users, and the development of science and technology. The government set a policy of Independent Learning-Independent Campus, or commonly known as Merdeka Belajar Kampus Merdeka, to set graduates ready to compete in the real career world. This concept was initiated by the government parallel to the theoretical perspective, giving students their rights to study outside their study programs in or outside the university; this is reckoned as a learning activity outside the university. From the perspective of utilitarian theory, this concept, set forth in the Regulation of the Minister of Education and Culture Number 3 of 2020, is intended to give countless benefits to university students as a whole to help them construct their hard and soft skills and to set them prepared to adjust to current development.
Evaluation of some Triticale (x Triticosecale Wittmack) cultivars and lines under Duzce ecological conditions
Authors: GÜNGÖR Hüseyin , ÇAKIR Mehmet Fatih , TURAN Yağmur , GEDİK Bahar , KANTAR Berkay Hakkı , DUMLUPINAR Ziya
Published: March 2023

This study was carried out with five triticale cultivars (Özer, Truva, Karma-2000, Alperbey and Tatlıcak-97) and 10 advanced triticale lines to determine the grain yield and yield components during 2020-2021 and 2021-2022 growing seasons under Duzce ecological conditions. In this study, the parameters of the genotypes such as spike length, number of spikelets per spike, number of grains per spike, grain weight per spike, thousand kernel weight, and grain yield were investigated. According to the two year results, whereas spike length, number of spikelets per spike, and number of grains per spike of genotypes changed 10.6-15.3 cm, 24.5-39.7, and 48.8-87.8, respectively, the grain related parameters such as grain weight per spike, thousand kernel weight, and grain yield were 2.518-4.261 g, 34.3-46.8 g, 720.2-1093.4 kg da-1, respectively. The highest yielding genotypes were found to be T-5, T-8, T-9 and Özer.
Differential expression of TIMP1 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding TIMP metallopeptidase inhibitor 1, TIMP1, when comparing colorectal tumors to the tissue of origin, the colon. TIMP1 mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of TIMP1 in rectal tumors was correlated with overall survival in patients with rectal cancer. TIMP1 expression changes may be important for the initiation or progression of human CRC.
Experiment ended
Authors: end exp
Published: March 2023

Need for Expansion of Regulations on Risky Pathogen Research Balancing the Cost and Ethics
A Scoping review: Nursing Human Resources Management During Pandemic COVID-19 in Emergency Department
Authors: Ramdani Wawan Febri , Wulandari Endah Tri
Published: March 2023

Abstract:Background: The COVID-19 pandemic has changed the order of service in the emergency room, which is the frontline in emergency services to save lives and prevent patient disability. Accepting referral patients who need follow-up treatment shows that the emergency room is the storefront of a hospital. Therefore, HR management is vital in responding to the COVID-19 pandemic.Purpose: Knowing the picture of HR management during the COVID-19 pandemic in the emergency room. Method: The writing of this article is a literature review with a scoping review.Results: This article found four things, namely nursing HR management in the emergency room, namely recruitment, staffing, shifting, and nursing HR management.
Tinjauan Pustaka
Authors: Wahyuni Andi Eka
Published: March 2023

Tinjauan Pustaka tentang ilmu Gizi pada materi zat makro
Experiment ended
Authors: end exp
Published: March 2023

Unlocking the Cost and Ethics of Science An Analysis of Open-Access
Rethinking Property Law through Plural Sovereignties
Authors: Sakshi
Published: March 2023

In this paper, I argue that law has an epistemic responsibility to rethink the proprietary language in light of plural sovereignty. Such responsibility involves questioning the complicity of law in perpetuating structural injustices and historical erasures, especially manifesting in the ongoing violence of settler colonialism. Further, it also examines who has had a place at the table to determine the nature and functioning of property law and if there are ways to overcome the limitations and obfuscation of possessory language in thinking about land. However, this simple act of questioning is not another act of theoretical indulgence. Instead, it emerges from the imminent need to rethink and reconfigure the idea of the integrity of the law. I argue that the new legal theory with responsibility interrogates property law and explores the radical potential of law and land beyond the remit of property law, especially in the emerging forms of climate and environmental litigation.
Tinjauan pustaka
Authors: Wahyuni Andi Eka
Published: March 2023

Tinjauan Pustaka Ilmu gizi Zat makro kesehatan masyarakat
Science Hard and Soft: An Empirical Approach to Evaluating Scientific Consensus with Big Data
Authors: Cook Gavin G. , Xie Yu
Published: March 2023

Though the terms “soft science” and “hard science” have long been used in both popular and academic discourse, many scholars of science studies argue that the hard–soft distinction does not exist. While the two most active fields of science studies, the science of science and the ethnography of science, have largely ignored questions of inter-field difference, the Mertonian school of the sociology of science explored how science varies between fields at length. We return to this age-old question with new data, theoretical approaches, and computational techniques. We first conduct a survey of the educated and general public to determine general perceptions of the hard–soft hierarchy in the sciences. We then merge contemporary advances in science studies with classical work in the sociology of science to create 14 metrics that explore the practice of science using big data. We find that the hard–soft spectrum exists, and public understandings of the spectrum comport almost exactly with empirical measures of hardness. We conclude by illustrating how a focus on inter-field variation in scientific practice can enrich current work on science studies.
The Effect of Customer Satisfaction on Loyalty: A Moderating Role of Corporate Communication in the Banking Sector
Authors: Mishra U.
Published: March 2023

In the 21st global competitive arena, the ultimate objective of any institution is to transform satisfied customers into loyal customers. Customer loyalty is highly affected by the satisfaction they obtain out of any service. Therefore, it is crucial to understand the relationship between customer satisfaction and customer loyalty. This study aims to examine the effect of customer satisfaction on customer loyalty with the mediating role of corporate communication. To collect data for the study, a convenience sampling method was used and 275 customers from different banks in Biratnagar participated in the survey. Structural equation modeling (SEM) was used to test the proposed hypothesis. The results depict that customer satisfaction positively and significantly associates with customer loyalty and this association is also strongly mediated by corporate communication. Moreover, corporate communication has a direct and positive influence on customer loyalty. This study has theoretical implications as it provides a better understanding of the relationship between satisfaction and loyalty.
गुरुप्रसाद मैनालीको 'कर्तव्य' कथाको परिस्थितिगत सन्दर्भ {Situational context of Guru Prasad Mainali's story of 'duty'}
Authors: थापा Thapa सीता Sita अधिकारी Adhikari
Published: March 2023

प्रस्तुत लेखमा आधुनिक नेपाली कथाकार गुरुप्रसाद मैनालीद्वारा रचित कर्तव्य कथाको परिस्थितिगत सन्दर्भ विश्लेषण गरिएको छ । यसका निम्ति सङ्कथन अन्तर्गतको सन्दर्भपरक विश्लेषणलाई सैद्धान्तिक आधारका रूपमा लिइएको छ । भाषिक अभिव्यक्ति अन्तर्गत वाक्यभन्दा माथिको एकाइ सङ्कथन हो भने सङ्कथन पाठभित्र अन्तनिर्हित सहभागी, भौतिक तथा संज्ञानात्मक सूचना प्रदान गर्ने विभिन्न परिस्थितिलाई सन्दर्भ भनिन्छ । सङ्कथन पाठमा प्रयुक्त भाषिक स्वरूप तथा त्यसको विशेष परिस्थितिक सन्दर्भको माध्यमबाट संज्ञान अर्थको खोजी गरिने प्रक्रिया सन्दर्भपरक सङ्कथन विश्लेषण हो । सङ्कथन पाठमा घटना, चरित्र र परिवेशले पनि सन्दर्भलाई सङ्केत एवम् विस्तार गरेको हुन्छ भने भाषाले सन्दर्भको निर्माण गर्ने तथा सन्दर्भले अर्थको प्रकटीकरण गर्ने भएकाले सङ्कथन पाठलाई संरचनापरक र सन्दर्भपरक कोणबाट अध्ययन विश्लेषण गरिन्छ । परिस्थितिगत सन्दर्भ विश्लेषण भाषाइतर पक्ष भएकाले सङ्कथनमा भाषिक प्रकार्य वा अभिव्यक्तिले दिने अर्थ र परिवेशमा समायोजित सन्दर्भलाई हेरिन्छ । सङ्कथनमा प्रयुक्त भाषाले सन्दर्भलाई प्रस्तुत गर्दछ भने सन्दर्भमा पाठको अर्थ समावेश रहने हँदा कर्तव्य कथामा रहेको सन्दर्भ तथा उक्त सन्दर्भले निर्धारण गरेको परिस्थितिगत अर्थहरूको खोजी सन्दर्भपरक अध्ययनका आधारमा गरिएको छ । प्रस्तुत लेखमा विवेच्य सङ्कथनमा कथाकार (समाख्याता) ले लेख्य अभिव्यक्तिका माध्यमबाट पाठनिष्ठ अर्थ निर्धारणका लागि वैयक्तिक, भौतिक र संज्ञानात्मक सन्दर्भको प्रयोगबाट सूचना संप्रेषण गरेका छन् । सामाजिक यथार्थवादी प्रवृतिको कर्तव्य कथामा सामाजिक विषयवस्तु, घटना, चरित्र र परिवेशका साथै भाषाको प्रयोगबाट विभिन्न सामाजिक–सांस्कृतिक सन्दर्भको निर्देश गरिएको हुनाले कथाको पारिस्थितिक सन्दर्भमा अर्थपूर्ण बनेको छ । व्यक्तिगत, पारिवारिक, सामाजिक–सांस्कृतिक यिनै विभिन्न परिवेशगत सन्दर्भहरूको प्रयोग भएको कर्तव्य कथालाई सङ्कथन विश्लेषणको परिस्थितिगत सन्दर्भका सैद्धान्तिक अवधारणामा आधारित भएर पाठपरक अध्ययन गरिएको छ । यसमा कृतिको सूक्ष्म पठनपद्धतिको प्रयोग गर्दै गुणात्मक ढाँचाको व्याख्या विश्लेषणात्मक विधिद्वारा शोध्य प्रश्नका प्राज्ञिक समाधान खोज्नु यस लेखको उद्देश्य रहेको छ ।
From Pilgrim to Local The Problem of Unity in Postmodern Philosophy
Authors: Klimsza Lucjan
Published: March 2023

In this article, the author outlines the problem of unity from the perspective of postmodern philosophy. Basically, unity of the human being is one of the most important problems of philosophy. Ancient philosophers identified human being as identical with citizenship. Man as a citizen of Athens was able to prove his citizenship of Athens by pointing to his ownership of family tombs and fireplace. Medieval philosophy continued the ancient idea but added one new aspect, hope. A medieval man was a citizen of the empire, but at the same time he or she was a citizen of Kingdom of Heaven. He or she was a pilgrim who travelled to God. Modern philosophy develops unity in an absolutely different way of thinking. First, what we have to know is that unity is a problem. Second, if we would like to solve this problem, it is absolutely necessary to use a new terminology. In this article I emphasize like to highlight the phenomenon of identity through an analysis that the Polish sociologist Zygmunt Bauman did in the past three decades. He divided a modern man into two categories. First, Bauman characterized a modern man as a global, very rich and well educated and can invest capital in all countries of the world. The second type is a local. He is a type of modern man who is not necessarily poor, but who is bound to only one place where he resides. The problem of the locals is that they cannot freely travel and invest in their own capital. Locals live in one place, they have not enough power to influence local politics, economy, infrastructure, religions. Globals are able to influence the local community by means of politics, economy, social structures, and religion. Zygmunt Bauman describes the identity of modern man as a tension between locals and globals.
Karakter Morfometrik Barbodes schwanenfeldii di Sungai Rupit Sumatera Selatan
Authors: Fatiqin Awalul , Amallia Ra Hoetari Tirta , Dhani Achmad Bagus
Published: March 2023

Barbodes schwanenfeldii is a fish that lives in the waters of the Rupit River, located in Karang Jaya District, North Musi Rawas Regency, South Sumatra. The purpose of this study was to determine the morphometrics of Barbodes schwanenfeldii in the Rupit River and the differences between Barbodes schwanenfeldii fish found in other rivers. This research uses purposive sampling method. The results of morphometric measurements of Barbodes schwanenfeldii obtained in the waters of the Rupit River are smaller than the Barbodes schwanenfeldii fish found in other river waters because, fish that have habitats living in water that have experienced metal pollution in the waters of the Rupit River have an impact on growth of fish.
Management of dynamic cervical kyphosis with dorsal epidural lipomatosis: a Hirayama disease variant? Illustrative case
Authors: Kundishora Adam J. , Reeves Benjamin C. , Moreno-De-Luca Andres , Hong Christopher S. , Robert Stephanie M. , Elsamadicy Aladine A. , Tuason Dominick , DiLuna Michael L.
Published: March 2023

BACKGROUND

Hirayama disease, a cervical myelopathy characterized most commonly by a self-limiting atrophic weakness of the upper extremities, is a rare entity, scarcely reported in the literature. Diagnosis is made by spinal magnetic resonance imaging (MRI), which typically shows loss of normal cervical lordosis, anterior displacement of the cord during flexion, and a large epidural cervical fat pad. Treatment options include observation or cervical immobilization by collar or surgical decompression and fusion.

OBSERVATIONS

Here, the authors report an unusual case of a Hirayama-like disease in a young White male athlete who presented with rapidly progressive paresthesia in all 4 extremities and no weakness. Imaging showed characteristic findings of Hirayama disease as well as worsened cervical kyphosis and spinal cord compression in cervical neck extension, which has not previously been reported. Two-level anterior cervical discectomy and fusion and posterior spinal fusion improved both cervical kyphosis on extension and symptoms.

LESSONS

Given the disease’s self-limiting nature, and a lack of current reporting, there remains no consensus on how to manage these patients. Such findings presented here demonstrate the potentially heterogeneous MRI findings that can be observed in Hirayama disease and emphasize the utility of aggressive surgical management in young, active patients whereby a cervical collar may not be tolerated.
Compartment syndrome associated with vascular avulsion caused by transradial access in neurointervention for unruptured intracranial aneurysm: illustrative case
Authors: Fuga Michiyasu , Tanaka Toshihide , Tachi Rintaro , Tomoto Kyoichi , Okawa Shun , Ishibashi Toshihiro , Hasegawa Yuzuru , Murayama Yuichi
Published: March 2023

BACKGROUND

Transradial access (TRA) has a lower risk of access-site complications than transfemoral access but can cause major puncture-site complications, including acute compartment syndrome (ACS).

OBSERVATIONS

The authors report a case of ACS associated with radial artery avulsion after coil embolization via TRA for an unruptured intracranial aneurysm. An 83-year-old woman underwent embolization via TRA for an unruptured basilar tip aneurysm. Following embolization, strong resistance was felt during removal of the guiding sheath due to vasospasm of the radial artery. One hour after neurointervention via TRA, the patient complained of severe pain in the right forearm, with motor and sensory disturbance of the first 3 fingers. The patient was diagnosed with ACS causing diffuse swelling and tenderness over the entire right forearm due to elevated intracompartmental pressure. The patient was successfully treated by decompressive fasciotomy of the forearm and carpal tunnel release for neurolysis of the median nerve.

LESSONS

TRA operators should be aware that radial artery spasm and the brachioradial artery pose a risk of vascular avulsion and resultant ACS and warrant precautionary measures. Prompt diagnosis and treatment are essential because ACS can be treated without the sequelae of motor or sensory disturbance if properly addressed.
Ischemic stroke caused by spontaneous anterior circulation intracranial arterial dissections: patient series
Authors: Furst Taylor , Ellens Nathaniel R. , Bender Matthew T. , Mattingly Thomas K.
Published: March 2023

BACKGROUND

Intracranial arterial dissections (IADs) are classically associated with the vertebrobasilar system, yet are a devastating cause of ischemic stroke within the anterior circulation. Current literature regarding the surgical management of anterior circulation IAD is lacking. As a result, data on 9 patients presenting with ischemic stroke due to spontaneous anterior circulation IAD between 2019 and 2021 were collected in a retrospective manner. Symptoms, diagnostic modalities, treatment, and outcomes are presented for each case. Patients who underwent endovascular procedures had 10-minute follow-up angiography performed to identify signs of reocclusion, which prompted initiation of glycoprotein IIb/IIIa therapy and stent placement.

OBSERVATIONS

Seven patients underwent emergent endovascular intervention (stenting: n = 5; thrombectomy alone: n = 2). The remaining 2 were managed medically. Two patients developed progressive flow limiting stenosis requiring further intervention, 2 developed asymptomatic progressive stenosis/occlusion with robust collateral formation and the remainder have patent vasculature upon follow up imaging at 6 to 12 months. Seven patients had a modified Rankin Scale score of 1 or less at the 3-month follow-up.

LESSONS

IAD is a devastating yet rare cause of anterior circulation ischemic stroke. The treatment algorithm proposed resulted in positive clinical and angiographic outcomes warranting future consideration and study in the emergent management of spontaneous anterior circulation IAD.
Advantages of altering cropping schedules in the face of climate variability: A case study of Tan Ky sugarcane cultivation area, Nghe An province
Authors: NGUYEN Q. C. , NGO H. Y. T. , VU M. H.T.
Published: March 2023

Tan Ky is known as one of the sugarcane cultivation regions (SCRs) of Nghe An Province, Vietnam. In recent years, the area is facing adverse weather factors, as a part of climate variability, resulting in a significant decrease in the income of cane growers. The study, therefore, is to estimate the benefits of the sugarcane growing practical (SGP) for the SCRs of Tan Ky district in the background of climate change and further seek effective adaptation solutions as well as optimize profits. Sugarcane yield was evaluated by simulating the APSIM-Sugar model (Version 7.0) based on the soil, crop varieties, field management and climate data during the period of 2000-21. The performance of the proposed model was appraised by comparing the simulated results with observed biomass and sugarcane yield data through the statistical indices with R2=0.83 ÷ 0.86, d=0.80 ÷ 0.88, and RMSE=0.16 ÷ 0.18. Results indicated that under the same cultivation conditions, the SGP in the adverse weather period could lead to a slight decline in the sugarcane yield around 6.8% for spring crop season compared to the favourable weather period. In general, the SGP across the SCRs of Tan Ky district are not suitable for the local cane growers and that may be one of the main causes leading to the decline in sugarcane yield and further decrease in cane growers’ incomes.
State and development of grain storage engineering and technologies in Ukraine
Authors:   State Enterprise Institute of Grain Crops of NAAN, Kyrpa М. Ya.
Published: March 2023

Topicality. These researches are due to the grain storage problem, the features of maize grain storage in metal silos under the various environmental factors, as well as more efficient using the material and technical facilities, including the grain storages of new generation. Purpose. To establish the types of grain storage facilities that are most appropriate for storing the yield of different crops, to improve metal silos and maize grain storage technologies. Materials and Methods. During experiments on maize grain storage, we used the metal silo equipped with a system of sensors to measure the temperature in different places of grain heap. We studied two models of grain storages, such as a standard construction (control) and an experimental one thermal isolated with a polyurethane layer. During the storage experiment, grain quality was monitored on grain moisture content, dockage, damage and germination. Results. Different types of grain storage facilities storing main volume of grain harvest were characterized; the technical, economic and technological advantages and disadvantages of grain storage were highlighted; directions for further development are outlined. The features of maize grain storage in the metal silos under influence of external meteorological conditions for 60 day were established. Temperature fluctuations were 7.1–13 °С in grain storage with thermal insulation, 4.5–25.9 °С – without insulation. As a result of significant temperature fluctuations, the grain was moistened by 2.2 %, its acidity increased by 1 degree, germination decreased by 7 %. At the stage of preparation for storage, maize grain should be cleaned to purity of 93–97 % by removing grain impurities. An effective method for this is fractional separation of grain. Conclusions. Thermal insulation of metal silos significantly reduces the negative impact of fluctuations in ambient air temperature, stabilizes the storage mode, and ensures high quality maize grain. The stability of grain during storage increases in the case of selection from it a fraction of grain of small, unfilled, with a low 1000 grain weight. Key words: types of grain storage facilities, metal silo, thermal insulation, maize, quality, cleaning grain before storage
The results of studying the productivity indicators of three-line sunflower hybrids and their parental forms under the influence of weather conditions
Authors:   Institute of Oilseed Crops NAAS, Kutishcheva N. M. , Shudria L. I. ,   Institute of Oilseed Crops NAAS, Odinets S. I. ,   Institute of Oilseed Crops NAAS, Bezsusidnii O. V. ,   Institute of Oilseed Crops NAAS, Sereda V. O. ,   Institute of Oilseed Crops NAAS
Published: March 2023

Topicality. At the present stage, the basis of the Ukrainian economy is agricultural production. Agriculture is the only sphere that is as dependent on weather fluctuations as any other. And it constantly has to adapt to the ongoing climate change. Climate changes, which cause an increase in temperatures, changes in the amount of precipitation and its distribution during the growth season, unstable weather conditions, the spread of pests and diseases, threaten the production of sunflower hybrids. The question about the influence of weather factors on the formation of productive traits of both hybrids and their parental forms, the dependence of agricultural crops on weather factors (temperature and precipitation, both for the entire growth season and for several months) is relevant. Purpose. To study of the influence of weather conditions on the formation of productive traits of hybrids and their parental components. Materials and Methods. The triple hybrids of sunflower (Helianthus annuus L.) Ahent, Ahronomicnyi, Kameniar, Marshal, Zaporizkyi 28, their parental components – single-cross sterile hybrids ZL(22х102)A, ZL(42х46)A, ZL(42х58)A and the restorers of fertility ZL512Rf, ZL678Rf and ZL7034Rf were studied. Results. Over the years of research, yield fluctuations reached to 0.90 t/ha for Ahent hybrid, 1.66 t/ha – Agronomichnyi, 0.13 t/ha – Marshal, 0.96 t/ha – Kameniar and 0.58 t/ha – Zaporizkyi 28. The highest yields and oil yield per unit area were in 2018. According to the results of three-year trials on hybrids and their parental forms, the Marshal hybrid had the highest yield – 2.64 t/ha with seed oil content of 50.78 % in 2016. Also in 2016, all pollen fertility restorers had the highest yields and oil yields. In 2018, four out of five hybrids showed the highest yields and oil yield per unit area. In 2017, the lowest oil content in the seeds of the tested hybrids was in the range of 45.16–48.49 % for Ahent and Zaporizkyi 28, respectively. Conclusions. It was established that Marshal is the most productive hybrid for sunflower cultivation in the southern Steppe of Ukraine, its average yield was 2.56 t/ha that exceeded by 0.27–0.48 t/ha this indicator in other hybrids. Key words: sunflower, hybrid, yield, oil content, 1000 seeds weight, oil yield, weather conditions, precipitation, temperature, sum of active temperatures, correlation coefficient
How Are the Karamojong Politically Marginalised?
Authors: Okoth Henry Okidi
Published: March 2023

The paper discusses the overlooked political marginalisation of Karamojong pastoralists in Uganda, contrary to a commonly held belief that ecological factors and pastoralism are the leading contributors to poverty and underdevelopment in Karamoja. Anchored within the theoretical strand of marginalisation, this article discusses how the actions of those operating at the centre of power perpetuate persistent poverty in Karamoja. A particular focus is placed on political representation, resource allocation and the engagement of local people in poverty eradication and development. The paper argues that the grants from central government are meagre and misguided, Karamoja is poorly and ineffectively represented at policy levels, and the local people have a limited voice in poverty alleviation and development programmes. The paper concludes that Karamoja's persistent poverty is to a great extent a product of political marginalisation. Finally, it recommends affirmative action, effective local leadership, sensitisation and involvement of local people in poverty alleviation initiatives and combating corruption in public offices.
Chromogranin A: As A Tumor Marker for Neuroendocrine Tumors Diagnosis, Follow-up & Its Correlation with Response to Somatostatin Analogues
Authors: Mohammed AL-Naqqash Manwar A.
Published: March 2023

Background: Chromogranin A is a useful tumor marker for neuroendocrine tumors (NETs) diagnosis & follow-up, Octreotide (somatostatin-long acting repeatable (SAS-LAR)) is an established treatment for NETs. Studies regarding the relation between response to SAS-LAR & the change in Chromogranin A (CgA) plasma level are still lacking.Objectives: To determine the association between the using of Octreotide (SAS-LAR) and CgA level on time sequence & clinical status.Patients & methods: a prospective observational study included 38 neuroendocrine patients in The Oncology Teaching Hospital/medical city complex/Baghdad, started at September 2013 till May 2016; assessing their circulating chromogranin A (CgA) plasma levels on multiple occasions(0,2 and 4 months) by ELISA technique and its correlation with response to somatostatin analogues (SAS-LAR) in those patients.Results: the study recruited 38 neuroendocrine patients. 21 (55%) of them were males, 23 (60%) patients were older than 50 years old & 17 (44%) had metastasis to different sites. Somatostatin analogues (octreotide 30mg) was administered to 20 out of 38 (52.6%) studied patients. Serial CgA tests were performed in (17 out of 20) patients used SAS-LAR, with a change in mean value from (225.3 U/L) pre-using the agent to (17.5 U/L) two months after its use & to (8.7 U/L) four months after its use (p=0.009, p=0.002 respectively) while the change in mean of CgA level was from (205.9 U/L) to (200.9 U/L) in 10 patients who did not use Octreotide (p=0.2).Also results showed that no statistically significant difference in mean value of CgA pre & two months after using Octreotide with regard to grade of the tumor.Conclusions: Plasma CgA is a reliable marker for NETs (regarding diagnosis, prognosis and response to treatment including somatostatin analogues).All patients with NETs should undergo a baseline plasma CgA level at diagnosis. Serial assessment of circulating CgA could be done for NET patients when there is baseline elevation of CgA level in circulation
Use of the experimental designs as an approach to optimize the inhibition efficiency of a Pyridazine derivative against corrosion of steel in an acidic medium
Authors: Forsal Issam , Bouchaib Mernari , Yassine Elkhotfi , Khalid Benbouya
Published: March 2023

In this manuscript, our aim was to optimize the inhibitory performance of a pyridazine derivative against steel corrosion in a 1M HCl solution. The percentage of inhibitor efficiency depends on various parameters, including inhibitor concentration, solution temperature, and immersion time. Using the Dohlert matrix and NemrodW software, we conducted a study to determine the most influential parameters affecting the corrosion phenomenon. Based on preliminary knowledge, we selected three parameters: inhibitor quantity, immersion time, and temperature. We evaluated the inhibitory efficiency by analyzing the Potentialdynamic intensity-potential curves and discussing the results obtained. Experimental designs offer benefits such as reducing the number of tests and detecting interactions between factors. By following the experimental design methodology, we aimed to determine the best conditions to obtain maximum inhibitor efficiency while reducing the number of required tests.
Analysis of the use of Sodium Bicarbonate for the performance of surfing athletes
Authors: Hanada Taliê Z. B. , Knack Rafael , Mayr Kamilla , Knack Renata S. , Guedes Dilmar , Scorcine Claudio , Pereira Rodrigo
Published: March 2023

PURPOSE: Surfing is a sport in which the intensity and duration of training varies. Therefore, strategies that contribute to muscle attenuation may be efficient to improve surfers' performance. OBJECTIVE: The aim of this study was to investigate the effectiveness of sodium bicarbonate on surfers' performance. METHODS: Eighteen male volunteer surf athletes participated in the study, in which they were instructed to perform up to twenty shots of twenty meters of paddling under their own surfboard in a swimming pool. The method was carried out twice, with an interval of 72 hours between them, being randomized between previous supplementation of sodium bicarbonate diluted in water, alternating with placebo containing sodium chloride and water. The blood lactate (Bla) was collected immediately before and after the rowing tests. RESULTS: The longest twenty-meter paddling shot time in the placebo group was 13.08 seconds (Bla 13.7 mg/dL after exercise) and the shortest was 9.89 seconds (Bla 15.1 mg/dL). On the day of bicarbonate ingestion, the longest time was 12.5 seconds (Bla14 mG/dL) and the shortest time was 9.1 seconds (Bla 15.5 mg/dL). CONCLUSIONS: The study showed that the administration of sodium bicarbonate positively affected the performance of surfers, resulting in a maximum improvement in paddle time and an increase in blood lactate.
Crossing between Conceptual Metaphor Theory and Text World Theory
Authors: Tincheva Nelly
Published: March 2023

The paper to seeks demonstrate that the academic notion of conceptual metaphorization on its own cannot account sufficiently for whole-text organization and structuring. The main line of argumentation is that, to achieve a better explanation of how whole text structuring happens in cognitive terms, we also need to account for the presence or absence of TW and DW overlap. The paper offers analysis of samples from political speeches, which confirms that the two theoretical systems (i.e. Conceptual Metaphor Theory and Text World Theory) are principally compatible, and that they are possible to cohere not only theoretically but also analytically. In sum, the paper argues in favour of harmonizing selected principles from the two theoretical cognitive frameworks and, hopefully, provides a step towards achieving greater cross-fertilization in text- and discourse-oriented cognitive research.
Implementation of Legal Protection for Economic Exploitation of Children
Authors: Kahnovich Yan , Rezki Annissa
Published: March 2023

Numerous parents utilize or even manipulate their children for their own profit. Typically, their treatment is motivated by money or economic issues. Numerous individuals immerse themselves in the demands of their existence without thinking about what they require and require. In this study, a qualitative descriptive methodology was employed. Based on the findings of this study, it was determined that there was a legal void in the implementation of criminal acts against offenders of economic exploitation of children. Even though the child's status in the eyes of the law has been accorded special protection, as stipulated in Law No. 23 of 2002 on Child Protection, this protection is not absolute. Children entitled to parental protection, affection, and supervision are educated and cared for in accordance with their rights as children so that there are no growth phase deviations. As an institution that concentrates on incidents of violence against children, the National Human Rights Commission can also demonstrate that numerous acts of violence have been committed against Indonesian children.Keywords: Legal Protection; Economic Exploitation; Child Exploitation
Anomali Status Kekayaan dan Piutang Badan Usaha Milik Negara
Authors: Nurhalimah Siti
Published: March 2023

Tulisan ini akan membahas kontradiksi antara dua putusan Mahkamah Konstitusi yakni putusan nomor 77/PUU-IX/2011 dan putusan nomor 43/PUU-XI/2013 terkait status kekayaan pada BUMN yang berasal dari modal negara. Pada putusan pertama, Mahkamah Konstitusi telah memisahkan piutang Bank BUMN dari piutang negara karena kekayaan BUMN dianggap sebagai kekayaan perseroan. Anehnya, pada putusan yang berbeda Mahkamah Konstitusi berpendapat bahwa kekayaan BUMN tidak dapat dikatakan kekayaan perseroan melainkan termasuk kekayaan negara.  Tulisan ini disusun berdasarkan penelitian yuridis normatif yang menjadikan peraturan perundang-undangan sebagai sumber hukum primer dan kepustakaan sebagai bahan sekunder. Tulisan ini menemukan bahwa dikeluarkannya Putusan Mahkamah Konstitusi Nomor 77/PUU-IX/2011 menyebabkan Bank BUMN dapat mengurus sendiri piutang yang dimilikinya. Adapun Putusan Mahkamah Konstitusi Nomor 48/PUU-XI/2013 tidak memberikan implikasi terhadap pengurusan piutang Bank BUMN yang telah diserahkan oleh PUPN kepada Bank BUMN untuk diselesaikan berdasarkan hukum perseroan.
Gerilla hadviselés a középkorban: a szász–frank háború (772–785)
Authors: Beck Attila
Published: March 2023

A 8. század utolsó harmadában, Európa egyik vezető katonai hatalma, a Frank Birodalom megkísérelte meghódítani a kisebb, de katonailag potens szász területeket. A rövidre tervezett hadjárat hosszú évekre elhúzódó háborúvá vált, amelyben a szász erők a gerilla hadviselés módszereit alkalmazták.
Miért a közigazgatás?
Authors: Szakács Édua
Published: March 2023

A fiatalok érdeklődése a közigazgatási pálya iránt az elmúlt évtizedekben csökkenő tendenciát mutatott, ráadásul a Diplomás Pályakövető Rendszer adataiból az is látszik, hogy a szakiárnyú képzettséget szerzett hallgatók jelentős része sem a közigazgatásban helyezkedik el, vagy rövid időn belül elhagyja azt. Jelen kutatásomban azt vizsgálom, hogyan hat az érintett fiatalok pályamotivációja a közigazgatási pályán való elhelyezkedés szándékára. A kutatásban a Nemzeti Közszolgálati Egyetem Államtudományi és Nemzetközi Tanulmányok Karának (NKE ÁNTK) 114 hallgatója vett részt. A résztvevők 65 százaléka volt nő és 35 százaléka férfi. A minta 71 százaléka volt nappali tagozatos és 29 százaléka levelezős hallgató. Hipotéziseimmel összhangban a kutatás eredményei igazolták, hogy a megkérdezett hallgatók inkább külső, mint belső pályamotivációval rendelkeznek, ami negatív hatással van a pálya iránti érdeklődésükre. A résztvevők érdeklődése a közigazgatási pálya iránt az egyetemi évek alatt csökkenő tendenciát mutatott. Ez a hatás a legerősebben a legfiatalabb, nappalis válaszadók esetében volt tetten érhető. A kutatás során három motivációs módot – erős, identifikált és külső – tudtam azonosítani. A várakozásoknak megfelelően a külső motivációval rendelkezők érdeklődése volt a legkisebb, az erős motivációval rendelkezőké pedig a legnagyobb a pálya iránt. További kutatást igényel annak feltárása, hogy miérterősödik meg a külső motiváció a résztvevőkben az egyetemi évek alatt, és hogyan fordítható meg ez a tendencia.
Argument on infantry support gun on academic level (1920–1943)
Authors: Mátyás Botond Hunor
Published: March 2023

In this review I try to show that fruitful argument what happened in the columns of Hungarian military journal Magyar Katonai Közlöny and Magyar Katonai Szemle. Gunner officers of that period had no other choice than turn to academic level because of restrictions of Treaty of Trianon. They tried to solve the same problem, effective artillery support for infantry, but imagined different ways. I will review their articles below.
The Relationship Between Memory, Type, and Severity of Aphasia With Confrontation Naming in Post-stroke Patients With Chronic Aphasia
Authors:   Department of Speech Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran., Saber-Moghadam Reihaneh , Zeinalzadeh Afsaneh ,   Department of Physiotherapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran., Momenzadeh Mehrzad ,   Department of Physiotherapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran., Taghi Farzadfar Mohammad ,   Department of Neurology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Ghaemi Hamide ,   Department of Speech Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran., Sobhani-Rad Davood ,   Department of Speech Therapy, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: March 2023

Objectives: The brain’s widespread neural functions lead to aphasia in which the patients experience difficulties in cognitive and language functions. Memory, type, and severity of aphasia are associated with language and the naming process. In the current study, we investigated the relationship between memory, type, and severity of aphasia using the confrontation naming test in post-stroke patients with chronic aphasia. Methods: This research was a descriptive-analytic cross-sectional study. We selected 45 chronic aphasia patients aged 35-70 years. The participants with a mild to moderate score in Mini-Mental State Examination (MMSE) were assessed with the Persian naming test, Wechsler Memory Scale, and Persian Western Aphasia Battery. Results: There was a significant difference between memory with correct answers without a cue, correct answers with a semantic cue, and the total correct answers from confrontation naming (P<0.001, r=0.62; P=0.01, r=0.37; and P<0.001, r=0.71; respectively). Furthermore, the results indicated a significant difference between the type of aphasia with subtests of confrontation naming involving correct answers with semantic cues and total correct answers (P=0.02). Also, the results showed a significant difference between the severity of aphasia with correct answers without a cue, correct answers with a semantic cue, and the total correct answers from confrontation naming (P<0.001, r=0.77; P=0.03, r=0.31; and P<0.001, r=0.67; respectively). In comparing semantic and phonetic cues, memory, type, and severity of aphasia indicated significant association only with semantic cues. Discussion: There is an association between memory, type, and severity of aphasia with confrontation naming in patients with aphasia. The data have highlighted the importance of factors that need to be considered to formulate a comprehensive treatment plan to achieve further improvement in naming skills.
Parents’ Perceptions of the Problems in Children With Autism Spectrum Disorders: A Qualitative Study
Authors:   Department of Speech Therapy, Faculty of Rehabilitation, Semnan University of Medical Sciences, Semnan, Iran., Zareei Masume , Tohidast Seyed Abolfazl ,   Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran., Salmani Masoomeh ,   Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Published: March 2023

Objectives: Parents of children with autism spectrum disorder (ASD) have valuable experiences of the possible developmental problems and other issues of their children as the primary caregivers. The present study aimed to obtain proper information by considering these experiences using a qualitative approach to explain the parents’ perception of problems in their children with ASD. Methods: This study with a qualitative design was performed on 35 parents of children with ASD (33 mothers and 2 fathers) who were selected via purposive sampling. The study data were collected using semi-structured interviews, and all sessions were recorded and immediately transcribed verbatim. We followed the Graneheim and Lundman (2003) content analysis approach (a step-by-step extraction of meaning unit, initial codes, subtheme, and theme). Results: We extracted 5 main themes of developmental, language comprehension and expression, social communication, behavioral, and general health problems. Each of these mentioned themes has several subthemes. Discussion: According to the results, the parents’ perceptions and experiences of their ASD children’s problems were similar to the findings reported by experts in a few related studies. Given the lived experiences of the parents of children with ASD, they could help enrich the references regarding the problems of children with ASD. Such data should be considered during the assessment and intervention for this group of children.