bluuebunny/crossref_metadata_2025 huggingface dataset:
Comprehensive management of posterior shoulder instability: diagnosis, indications, and technique for arthroscopic bone block augmentation
Authors: Hachem Abdul-ilah , Molina-Creixell Andres , Rius Xavier , Rodriguez-Bascones Karla , Cabo Cabo Francisco Javier , Agulló Jose Luis , Ruiz-Iban Miguel Angel
Published: August 2022

Recurrent posterior glenohumeral instability is an entity that demands a high clinical suspicion and a detailed study for a correct approach and treatment. Its classification must consider its biomechanics, whether it is due to functional muscular imbalance or to structural changes, volition, and intentionality.

Due to its varied clinical presentations and different structural alterations, ranging from capsule-labral lesions and bone defects to glenoid dysplasia and retroversion, the different treatment alternatives available have historically had a high incidence of failure.

A detailed radiographic assessment, with both CT and MRI, with a precise assessment of glenoid and humeral bone defects and of glenoid morphology, is mandatory.

Physiotherapy focused on periscapular muscle reeducation and external rotator strengthening is always the first line of treatment. When conservative treatment fails, surgical treatment must be guided by the structural lesions present, ranging from soft tissue repair to posterior bone block techniques to restore or increase the articular surface.

Bone block procedures are indicated in cases of recurrent posterior instability after the failure of conservative treatment or soft tissue techniques, as well as symptomatic demonstrable nonintentional instability, presence of a posterior glenoid defect >10%, increased glenoid retroversion between 10 and 25°, and posterior rim dysplasia. Bone block fixation techniques that avoid screws and metal allow for satisfactory initial clinical results in a safe and reproducible way.

An algorithm for the approach and treatment of recurrent posterior glenohumeral instability is presented, as well as the author’s preferred surgical technique for arthroscopic posterior bone block.
Current understanding of tandem spinal stenosis: epidemiology, diagnosis, and surgical strategy
Authors: Bai Qiushi , Wang Yuanyi , Zhai Jiliang , Wu Jigong , Zhang Yan , Zhao Yu
Published: August 2022

Tandem spinal stenosis (TSS) is defined as the concomitant occurrence of stenosis in at least two or more distinct regions (cervical, thoracic, or lumbar) of the spine and may present with a constellation of signs and symptoms. It has four subtypes, including cervico-lumbar, cervico-thoracic, thoraco-lumbar, and cervico-thoraco-lumbar TSS. The prevalence of TSS varies depending on the different subtypes and cohorts.

The main aetiologies of TSS are spinal degenerative changes and heterotopic ossification, and patients with developmental spinal stenosis, ligament ossification, and spinal stenosis at any region are at an increased risk of developing TSS.

The diagnosis of TSS is challenging. The clinical presentation of TSS could be complex, concealed, or severe, and these features may be confusing to clinicians, resulting in an incomplete or delayed diagnosis. Additionally, a consolidated diagnostic criterion for TSS is urgently required to improve consistency across studies and form a basis for establishing treatment guidelines.

The optimal treatment option for TSS is still under debate; areas of controversies include choice of the decompression range, choice between simultaneous or staged surgical patterns, and the order of the surgeries.

The present study reviews publications on TSS, consolidates current awareness on prevalence, aetiologies, potential risk factors, diagnostic dilemmas and criteria, and surgical strategies based on TSS subtypes. This is the first review to include thoracic spinal stenosis as a candidate disorder in TSS and aims at providing the readers with a comprehensive overview of TSS.
The concept of the target complex educational project «Your friend is the Black Sea»
Authors: NESTERENKO L.V.
Published: August 2022

The article presents the concept of a comprehensive educational project «Your friend — the Black Sea» (Project) to attract a wide range of scientists, educators and the public to study and disseminate information about the Black Sea; education, enlightenment and popularization of knowledge about marine sciences and professions among children and youth. International experience in raising awareness in the field of oceanology is presented. It is assumed that the start of the Project will give impetus to the development of marine sciences in all levels of education and strengthen cooperation between states at all levels in the Black Sea.
Dinámica temporal de erosión del suelo en café (Coffea arabica), Llano Brenes, Costa Rica
Authors: Palominos-Rizzo Teresa , Villatoro-Sánchez Mario , Alvarado-Hernández Alfredo , Cortés-Granados Víctor , Paguada-Pérez Darwin
Published: August 2022

Introducción. La erosión hídrica es un fenómeno natural, acelerado por la actividad humana, que facilita la degradación de los suelos y el transporte de sedimentos a otras zonas. Objetivo. Cuantificar la escorrentía superficial y la tasa de erosión a escala de parcela, bajo eventos de precipitación natural, en un suelo Entisol sembrado con café (Coffea arabica) con sombra, y determinar la dinámica temporal y la influencia de los principales factores asociados con este proceso. Materiales y métodos. El estudio se desarrolló en Llano Brenes, Alajuela, Costa Rica. Se instalaron nueve parcelas de escorrentía, los datos fueron recolectados entre mayo de 2018 y noviembre de 2019, cada parcela tuvo un medidor de escorrentía y un contenedor para la toma de muestras de sedimentos. Se instalaron tres sensores de reflectometría de dominio temporal para las mediciones de contenido superficial de humedad del suelo. El análisis de datos se realizó a escala mensual-anual, inter-evento e intra-evento. En la escala intra-evento se utilizó el modelo de infiltración de Diskin y Nazimov. Resultados. En los años 2018 y 2019 se obtuvieron, respectivamente, los siguientes resultados anuales: a) lámina total de escorrentía de 90,99 y 102,66 mm, b) concentración de sedimentos de 2,14 y 1,88 g L-1, y c) pérdida de suelo de 1612 y 1692 g m-2. Los mayores valores de pérdida de suelo se obtuvieron en octubre de cada año; el análisis intra-evento explicó la generación de escorrentía con base la lámina de precipitación y el contenido de humedad inicial en el evento. Conclusión. La tasa de erosión y la escorrentía medias anuales fueron de 1652 g m-2 y 96,8 mm, respectivamente. La lámina de precipitación, intensidades y contenido inicial de humedad superficial del suelo tuvieron un importante rol en la generación de escorrentía y pérdida de suelo.
ANÁLISE DAS ESTRATÉGIAS DIGITAIS ELABORADAS PELA REDE MAGAZINE LUIZA DIENTE DO CENÁRIO DE PANDEMIA (COVID-19).
Authors: Da Cruz  Junior Antônio Fernandes
Published: August 2022

O presente artigo tem como objetivo principal analisar as estratégias digitais elaboradas pela rede Magazine Luiza diante do cenário de pandemia (COVID-19). Para execução deste artigo, se fez necessário a utilização do método qualitativo-descritivo-exploratório, com bases em pesquisas bibliográficas na área de gestão de marketing e uma pesquisa documental nos resultados divulgados pela própria companhia. Após realizar uma análise dos dados levantados, verificou-se a importância das estratégias elaboradas no ambiente digital e a utilização de um portal de serviços eletrônicos. Desse modo, a utilização das tecnologias da informação e da comunicação impõe novas estratégias para expansão e ampliação de serviços e produtos.
ANÁLISE DAS ESTRATÉGIAS DE MARKETING DESENVOLVIDAS PELAS EMPRESAS DE ALIMENTAÇÃO DE JOÃO CÂMARA PARA SE MANTEREM NO MERCADO PERANTE OS IMPACTOS CAUSADOS PELO COVID-19
Authors: Santos Maria Leticia da Silva , Silva Andréa Dantas Costa da , Medeiros Antonia Luana Amaro , Silvino Marilson Donizetti
Published: August 2022

Pretende-se neste projeto de pesquisa analisar quais estratégias de marketing que foram realizadas e desenvolvidas pelas empresas, as mudanças e adaptações que os estabelecimentos no setor alimentício vivenciaram na cidade de João Câmara, para se manterem no mercado durante a pandemia do novo coronavírus. Será realizada uma pesquisa de campo junto a algumas empresas do setor alimentício da região de João Câmara, serão entregues formulários com perguntas específicas sobre quais estratégias de marketing foram utilizadas por determinadas empresas no período da pandemia. A pesquisa será fundamentada teoricamente por citações de autores, sites, revista, entre outros na área do marketing, marketing digital e estratégias de marketing. Se espera que o desenvolvimento deste trabalho consiga diagnosticar quais as estratégias foram utilizadas pelas empresas na Região do Mato Grande neste momento de enfermidade epidêmica amplamente disseminada, para que possa encontrar possível melhorias e inovações para empresas que atuam na área da alimentação.
On the maintenance experience of navigational hydraulic structures database
Authors: Kolesnikov Yury
Published: August 2022

To make effective management decisions in the safety measures field of navigational hydraulic structures, versatile information support is required, which is implemented, including by maintaining a database on them. This achieves the industry scale formation of a reliable set of information on various reliability and safety operational issues of navigational hydraulic structures, ensuring timely detection (forecasting) and prevention of crisis situations on them. The industry database includes information on pressure water transport hydraulic structures subject to declaration in accordance with the legislation on the safety of the hydraulic structure. The automated navigational hydraulic structures database is an information and analytical complex operating on a computer technology basis, which allows you to accumulate and store a variety of information, correct it, process, select and analyze, including retrospective, etc. The author of the article notes that for the implementation of the state policy in the safety measures field of industrial facilities, it is necessary to improve the work organization in the field of timely detection and prevention of man-made and natural threats, the technical basis for monitoring, which is the most important condition for increasing the reliability and efficiency of obtaining comprehensive information characterizing its safety state. Based on the processing and analyzing complex information results, the article characterizes the state of navigational hydraulic structures, provides suggestions and recommendations aimed at ensuring their safe operation for the purpose of prompt response, implementation of corrective actions in the inter-declaration period, as well as for planning for the future, an assessment is made the effect of repair and restoration work performed at hydraulic structures at different times.
Adaptive digital technological regulations development for engineering and intellectual support for the railway track facilities construction
Authors: Polyanskiy Aleksey
Published: August 2022

The article considers the developing possibilities of adaptive digital technological regulation for the railway track facility construction. Railway construction as a complex dynamic system requires certain resources for its maintenance. At the same time, it is characterized by the use of new, more advanced design solutions, materials, and technologies, the performers' specialization development, and a large number of participants in the technological process associated with this. Under these conditions, effective control over the job practices performed during the railway track facilities construction is of decisive importance. This can be achieved by improving the existing engineering system and technical support for railway construction through the subsystem introduction for engineering and intellectual support of technological processes for the railway facilities construction. One of the tasks of engineering and intellectual support of technological processes is the effective use of automated systems, including those with artificial intelligence elements. Their creation and implementation are focused on achieving a single endresult: a finished railway track facility of the appropriate functional purpose within the established time frame, planned cost and labor costs and also meeting modern safety requirements throughout the entire operation period. As part of the methodology formation for engineering and intellectual support of railway construction technological processes, the structure of an adaptive digital technological regulation was developed - a digital regulatory document that defines the norms and rules for conducting the technological process of building a railway facility. A distinctive feature of the adaptive digital technological regulations is the possibility of its adjustment in an automated mode. The purpose of the adjustment is to adapt the technological process to the changing working conditions and the resource equipment of construction (contractor) organizations. At the same time, the information contained in the regulations can be transferred to 4D design and construction project management systems.
Based on the theoretical study results, the article presents practical aspects of the automated development of adaptive digital technological regulations on the example of the flooded railway roadbed construction.
The results presented in the article were obtained in the dissertation course research carried out by the author.
Soil slope analysis to develop useful correlations in saturated and unsaturated conditions
Authors: Khan Muhammad Israr , Wang Shuhong , Wang Pengyu , Nikjow Mohammad Ajmal
Published: August 2022

Shear strength (τ), shear stress (σ s) and slope angle (β) play a very important role in the stability of any soil slope. This research investigates the slope stability of a soil slope to determine correlations between shear strength and slope angle and shear stress. The assessment and calculation of the soil slope are carried out using slope stability analysis methods that assume the failure surface as a circular slip surface. A limit equilibrium software program – namely, Slide – and a numerical modelling software program – namely, Statistical Package for the Social Sciences – are used for the analysis. Total 200 number of analyses were performed out of which 100 analyses in saturated and 100 in unsaturated condition. Correlations are developed between τ, β and σ s, which show a very close relationship among all these three parameters. The applicability of the equations is above 97%. The correlations can be used in any slope stability project to know about the shear strength of the slope with variation in the values of the slope angle and shear stress.
Influence of particle size on the small-strain stiffness in granular soils: experimental observations and micromechanical interpretation
Authors: Sarkar Debdeep , Goudarzy Meisam , Wichtmann Torsten
Published: August 2022

The aim of the current study is to provide evidence regarding the influence of particle size on the dynamic properties in granular materials. Experiments using a resonant column (RC) device were conducted on glass beads having similar coefficient of uniformity, but four different mean grain sizes to describe the tendencies in the magnitude of Gmax and Emax. It can be clearly seen that for similar particle gradation the influence of particle size is significant, in particular for larger mean grain sizes d50 exceeding 1·5 mm. The experimental data were fitted using existing empirical relationships with corresponding fitting parameters. The fitting parameters describing the void ratio and pressure dependence to estimate maximum stiffness were found to depend on grain size to a certain extent. This influence was diminished for the materials with a d50 < 1·5 mm. It was therefore possible to use a unique set of fitting parameters for these materials with a satisfying degree of accuracy. The results were compared with some previous studies to highlight the size dependency of Gmax and Emax for materials with mean size greater than 2 mm, but also the relatively small influence on materials with lower mean particle sizes (d50 < 2 mm) is acknowledged. The results are furthermore discussed through a micromechanical interpretation highlighting why larger grain sizes influence stiffness values.
Hyper-Variable Spike Protein of Omicron Corona Virus and Its Differences with Alpha and Delta Variants: Prospects of RT-PCR and New Vaccine
Authors: AK Chakraborty
Published: August 2022

NCBI SARS-CoV-2 Database was analyzed between November-December, 2021 to decipher the spread of Delta corona virus variants in the USA and compared with highly transmissible new omicron variant recently originated in South Africa. Presently, B.1.617.2 and AY.103 lineages Delta variants with spike protein L452R, T478K, P681R mutations and F157/R158 two amino acids deletions were predominant in the USA and superseded the deadly outbreaks of B.1.1.7 Alpha variant with deletions of H69, V70 and Y145 amino acids as well as N501Y, and D614G highly transmissible mutations. Interestingly, omicron variant has six H69, V70, V143, Y144, Y145, L212 immune-escape deletions as well as 29 mutations in the spike protein including most deadly N501Y (Y498 in omicron) and D614G (G611 in omicron). This indicated that omicron variant was originated by combination among B.1.1.7, AY.X and B.1.617.2 lineages. A unique three amino acids (EPE) insertion at 215 position of spike protein was detected to compensate six deletions suggesting further recombination events. Three Serine residues were mutated at amino acids 371 (S=L, L368 in omicron), 373 (S=P, P370 in Omicron), 375 (S=F, F372 in omicron) but compensated at 446 (G=S, S443 in omicron) and 496 (G=S, S493 in omicron) at the RBD domain of omicron virus. The three amino acids (ERS) deletion at position 30 in the N-protein acts as another signature of omicron virus. Omicron variant has less mutation in the 2/3 5’-end of the genome that codes for ORF1ab poly-protein but dominant P4715L mutation in the RNA-dependent RNA polymerase. However, overall amino acid composition, alipathic index, and instability index were found fairly constant although hydrophobic plot gave some difference between spike protein of Wuhan and omicron corona viruses. BLAST search detected 20nt and 19nt perfect match of hyper-variable 22957-22977nt region comprising 488-493 amino acids (NH2-PLRSYS-CO2H) of the spike protein of omicron virus with the ch-2 of Seladonia tumulorum or ch-16 of Steromphala cineraria respectively. A primer set designed from the RBD domain of spike gene did not detected the omicron genome by BLAST search but primers from the constant regions of the genome worked well. Such hyper-variation in the spike protein suggested that DNA vaccine or mRNA vaccine using spike gene of corona virus may not efficiently protect omicron virus infection and attenuated whole corona virus vaccine will be safer vaccine.
A Wilder Joyce: Influence, Borrowing, Appropriation, Theft
Authors: Gontarski S. E.
Published: August 2022

This article re-examines the unintended consequences of American novelist and playwright Thornton Wilder’s lifelong passion for the work of James Joyce, as Wilder was writing what would become his second Pulitzer Prize winning play, The Skin of Our Teeth, while in the midst of ‘unriddling’ Joyce’s final novel, Finnegans Wake. Subsequently, accusations of plagiarism arose from two major Joyce scholars, Joseph Campbell and Henry Morton Robinson, who not only questioned the borrowings of a particular playwright in creating a new artwork for the stage but also challenged the practices of commercial theater and contemporary theories of originality and textuality. Exploring The Skin of Our Teeth as an intertext, on the other hand, simultaneously validates Campbell and Robinson’s initial assessment and encourages a rethinking of Wilder’s commitment to Joyce as both a scholar and something of a collaborator. Such a shift would allow the critical community to ask theoretical questions about how this ‘collaboration’ works to afford accessibility and so opens Finnegans Wake to a wider audience. Wilder might thus be seen as offering something like a thematic catalogue to the novel in parallel to the ‘theme keys’ he outlined in his Joyce journals. Such recalibration would reposition Wilder’s contributions, not only as an American playwright but as a pioneering critic and crusading intellectual: a European-focused writer wholly in the American grain, an avant-garde champion like his compatriot Edmund Wilson, one who could recognize, invoke, and engage simultaneously with the European avant-garde and the American theatrical and critical traditions.
Scanning Electron Microscopy - Focused Ion Beam Biological Sample Preparation v1
Authors: Parisi Ludovica
Published: August 2022

The combination of the scanning electron microscopy (SEM) with a focused ion beam (FIB), represents a pioneering and interesting tool to allow the investigation of the relationship occurring at the interface between cells and biomaterials. Herein, we provide a suitable protocol for cell-biomaterial sample preparation before imaging by SEM-FIB.
Centriflaken: an automated data analysis pipeline for assembly and in silico analyses of food-borne pathogens from metagenomic samples v2
Authors: Konganti Kranti
Published: August 2022

Rapid and comprehensive analysis of metagenomic data from any sample is of importance in food safety. Also important is the need for automated analysis pipelines allowing rapid and effective construction of metagenomic assembled genomes (MAGs) to enable bacterial source-tracking from metagenomic data. We developed a precision metagenomics approach for detecting and classifying shiga toxin-producingEscherichia coli (STEC) in enrichments of agricultural water using Oxford Nanopore long read sequencing where the bioinformatics data analysis employed many sequential manual steps (Maguire et al, 2021). Here we present centriflaken, a suite of automated data analysis workflows enabled by Nextflow, which takes metagenomic data and generates MAGs and performs in silico-based analysis as described in Maguire et al, 2021. The final summary plots and tables can be downloaded from the provided MultiQC HTML report generated as part of the pipeline. The centriflaken pipeline was validated with data from our previously published method and was able to replicate the detection and classification of STECs for each sample. We tested the pipeline with nanopore data obtained from 21 additional enriched samples from irrigation water and was able to perform the entire precision metagenomics analysis in less than 5 hours. We have further expanded this precision approach to include any user supplied taxa of interest (Listeria monocytogenes or Salmonella) not only STECs.
The Organization of Turkic States: Implications for the Regional Balance of Power
Authors: Demir Can
Published: August 2022

Three decades of close relations in the Turkic world have brought about several platforms of cooperation built on a common cultural basis. As the last in the series, the Organization of Turkic States bears the hallmark of a full-fledged international organization of the whole Turkic world with a strong vision for the next two decades. This study examines the dynamics of the organization, which is expected to become a significant international actor in Eurasia, owing to the increasing synergy among the Turkic States. In this regard, the study aims to analyse the implications of the emergence of the Organization of Turkic States as an international actor for the regional balance of power in Eurasia. To this end, the SWOT analysis method is used to specify the organization’s strengths, weaknesses, opportunities, and threats, which lead to general implications. The Organization of Turkic States is sure to be a power to be reckoned with among superpowers having interests in the Eurasia region in the long term.
Tolerância de cultivares de soja à toxicidade do alumínio em fase inicial
Authors: Cabral Rogério do Carmo , Zuffo Alan Mario , Ensinas Simone Cândido , Silva Kátia Cristina da , Steiner Fábio
Published: August 2022

Os genótipos de soja possuem níveis distintos de tolerância aos efeitos fitotóxicos do alumínio (Al3+) e a exploração dessa característica pode ser uma importante estratégia para potencializar o uso de solos ácidos. Esta pesquisa foi realizada para investigar os efeitos do alumínio na germinação e no crescimento inicial de 25 cultivares de soja, e identificar os cultivares mais tolerantes e suscetíveis à toxicidade por Al3+. O ensaio foi realizado no laboratório de sementes da Universidade Estadual de Mato Grosso do Sul, Unidade Universitária de Cassilândia. A toxicidade de Al3+ foi imposta pela exposição das sementes a uma solução diluída contendo 15 μmol L–1 de Al3+, combinada com 1250 μmol L–1 de cálcio. O pH da solução contendo Al3+ foi ajustado para 4,3 com HCl 0,5 mol L–1. O delineamento experimental utilizado foi o inteiramente casualizado com quatro repetições de 50 sementes. Os fatores foram constituídos pelas 25 cultivares de soja e pelas duas condições de crescimento das plântulas (controle ou estresse por Al3+), totalizando 50 tratamentos. Os tratamentos foram avaliados com base nos índices de tolerância ao estresse (ITE) para a germinação das sementes, comprimento e matéria seca das plântulas. A toxicidade por Al3+ reduziu a taxa de germinação e o crescimento inicial de todas as 25 cultivares de soja. As cultivares TMG 7061 IPRO, TMG 7063 IPRO, TMG 7067, HO Paranaíba IPRO e NS 7505 IPRO foram consideradas como as mais indicadas para serem cultivadas em solos ácidos por apresentarem maior tolerância à toxicidade de alumínio, e as cultivares RK 815 IPRO, RK 8317 IPRO e ST 777 IPRO foram classificadas como suscetíveis à toxicidade do alumínio, e não devem ser recomendadas para o cultivo em solos ácidos.
Monitoramento da eficiência de sistemas de transporte de aves até o abatedouro
Authors: Guimarães Júnior Djalma Silva , Sant'Anna Carlos Henrique Michels de , Rodrigues Maurilio
Published: August 2022

A combinação da ampliação da renda da sociedade e da capacidade de produção nas últimas décadas tornaram o setor avícola essencial. Dada a competitividade do mercado, o segmento opera com pressões por redução de custos e eficiência nos processos. Sendo assim, um fator de desperdício para o segmento são as aves que morrem durante as operações de transporte dos criadouros para o abatedouro. Esta pesquisa pretende utilizar o Controle Estatístico de Processos para monitoramento do número de aves mortas no deslocamento da granja para o abatedouro, bem como inferir sobre a influência de fatores ambientais na morte das aves utilizando um modelo de regressão. O resultado deste trabalho foi o estabelecimento de uma carta de controle do processo que permite a separação das mortes inerentes ao processo, das mortes ocasionadas por fatores não aleatórios, que podem ser evitadas através de processos de gestão. Além disso, os resultados permitiram observar que temperaturas mais amenas contribuem para a diminuição do número de mortes, enquanto que temperaturas mais elevadas ampliam a mortalidade.
Respostas fisiológicas e morfoanatômicas de Bowdichia virgilioides Kunth. (Fabaceae) submetidas ao herbicida paraquat
Authors: Oliveira Ana Paula Augusta de , Costa Alan Carlos , Crispim Filho Ailton Jose , Freitas Dhesy Allax Cândido de , Silva Kellen Lagares Ferreira
Published: August 2022

O avanço do agronegócio tem sido evidente e em consequência disso observa-se o aumento do uso de herbicidas. Em vista disso, objetivou-se avaliar as respostas fisiológicas e morfoanatômicas em plantas de Bowdichia virgilioides Kunth (Fabaceae), quando expostas ao herbicida paraquat, em condições controladas de casa de vegetação, e identificar possíveis padrões de respostas da espécie estudada, com o propósito de fornecer subsídios para o estudo da espécie, em áreas atingidas por deriva desse herbicida e/ou aqueles que possuem o mesmo mecanismo de ação. O delineamento foi em blocos ao acaso, com oito doses do herbicida, sendo: 25, 50, 100, 200, 400, 800 e 1200 g i.a ha-1 e o controle (0), com quatro repetições para cada uma das doses. Foram analisados: trocas gasosas, emissão de fluorescência da clorofila a, conteúdo de pigmentos cloroplastídicos, permeabilidade de membrana e análises visuais e anatômicas. Os resultados mostraram que o paraquat é fitotóxico para B. virgilioides, pois, mesmo em doses baixas esse herbicida foi capaz de afetar todos os parâmetros analisados, causando inclusive a morte das plantas em doses mais elevadas. Houve também a confirmação da presença de compostos fenólicos. As respostas observadas neste estudo podem servir como ferramenta de diagnóstico dos efeitos desse herbicida sobre plantas jovens dessa espécie em fragmentos vegetais atingidos pela deriva desse herbicida.
Efeito do regulador de crescimento cloreto de clormequate nos atributos morfométricos e produtivos de plantas de soja
Authors: Basilio Alex Fernando , Souza Clovis Arruda , Cigel Camila , Kandler Rodrigo , Pinheiro Magaiver Gindri
Published: August 2022

O cultivo de soja em regiões de altitude estimula o crescimento de estruturas vegetativas e diminui as reprodutivas. O uso de reguladores de crescimento favorece a efetivação de estruturas reprodutivas. Objetivou-se avaliar variáveis morformétricas e componentes de rendimento de soja sob aplicação do regulador de crescimento cloreto de clormequate. O experimento foi conduzido em casa de vegetação no munícipio de Lages (SC), Brasil, na safra 2018/19. O delineamento experimental foi em blocos ao acaso com cinco repetições, seguindo o arranjo fatorial 2 x 5 x 3: a) duas cultivares de soja, b) cinco doses do cloreto de clormequate (0, 25, 50, 75 e 100 g i.a. ha-1), c) três estádios de aplicação do regulador (V9, R1 e R3). Os resultados obtidos demonstraram que as aplicações no estádio V9 nas doses 75 e 100 g i.a. ha-1 tiveram maior efeito na redução de altura de plantas, pela redução do comprimento de entrenós, sem afetar o número de nós e de vagens por planta, e ainda incrementando o diâmetro da haste principal, desse modo aplicações nesses estádios podem controlar o excesso de crescimento vegetativo e evitar os problemas do acamamento.
Justiça e Legitimidade na Tributação: A Imunidade Implícita do Mínimo Existencial
Authors: Silveira Vladmir Oliveira da , Jaques Abner da Silva , Vasques Arthur Gabriel Marcon
Published: August 2022

A pesquisa tem por objetivo analisar o instituto da imunidade tributária, correlacionando-a à importância para a concretização dos valores erigidos enquanto direitos fundamentais dos contribuintes, principalmente os sociais. A justificativa, por sua vez, está relacionada à identificação de que certos valores auferidos não são riquezas novas ou fatos signos presuntivos para a capacidade contributiva, mas apenas numerários necessários à manutenção da subsistência do contribuinte com dignidade. Deste modo, considerando que há a necessidade de se promover uma ponderação da legitimidade da tributação com os direitos sociais, a pesquisa, valendo-se dos instrumentos de hermenêutica, busca, como problemática, responder se a Constituição Federal, além de seu rol descrito no artigo 150, inciso VI, reconhece a imunidade tributária implícita do mínimo existencial dos cidadãos. A pesquisa funda-se no paradigma dogmático do direito com ênfase em valores, e vale-se do método hipotético-dedutivo, com base em pesquisas bibliográficas e documentais, visando a elaborar um estudo exploratório e descritivo.
Criminalizar a Alienação Parental, ou Utilizar os Métodos Autocompositivos para Solucionar o Problema?
Authors: Ferrari Aline Alves Maciel , Oliveira Edmundo Alves de , Franceschet Júlio Cesar
Published: August 2022

A alienação parental se tornou conhecida no Brasil após a promulgação da Lei nº 12.318/2010 (BRASIL, 2010), que conceituou o tema e trouxe as condutas consideradas como alienatórias. Com a entrada em vigor da Lei nº 13.431/2017 (BRASIL, 2017), em 05 de abril de 2018, a alienação parental passou a ser considerada crime. No presente artigo serão analisadas as leis, a doutrina e a jurisprudência sobre o tema, com o objetivo de não só verificar se a aplicação de sanções aos responsáveis pela alienação parental serve para solucionar o problema, ou se pode servir como uma pena imposta à criança, mas também se a utilização dos métodos autocompositivos contribuem para a sua resolução. O método aplicado foi o hipotético-dedutivo, utilizando a técnica de revisão bibliográfica.
A Comprehensive Structural Classification of RAS Conformations
Authors:   , Parker Mitchell Isaac , Golemis Erica , Dunbrack Roland L.
Published: August 2022

For many human cancers and tumor-associated diseases, mutations in the RAS isoforms (KRAS, NRAS, and HRAS) are the most common oncogenic alterations, making these proteins high-priority therapeutic targets. Effectively targeting the RAS isoforms requires an exact understanding of their active, inactive, and druggable conformations. However, there is no structure-guided catalogue of RAS conformations to guide therapeutic targeting or examining the structural impact of RAS mutations. We present an expanded conformational classification of RAS conformations based on analyzing their catalytic switch 1 (SW1) and switch 2 (SW2) loops. From over 700 available human KRAS, NRAS, and HRAS structures in the Protein Data Bank (PDB), we first created a broad structural classification based on the spatial positions of residue Y32 in SW1 and residue Y71 in SW2. Subsequently, we defined further conformational subsets (some previously undescribed) by clustering all well modeled SW1 and SW2 loops using a density-based machine learning algorithm with a backbone dihedral-based distance metric. In all, we identified three SW1 conformations and nine SW2 conformations, each of which is associated with different nucleotide states (GTP-bound, nucleotide-free, and GDP-bound) and specific bound proteins or inhibitor sites. The GTP-bound SW1 conformation can be further subdivided based on the hydrogen (H)-bond type made between residue Y32 and the GTP [gamma]-phosphate: water-mediated, direct, or no H-bond. Further analyzing these structures clarified the catalytic impact of the most common RAS mutations, and the inhibitor chemistries that bind to each druggable RAS conformation. To facilitate future RAS structural analyses, we have created a web database, called Rascore, presenting an updated and searchable dataset of all human RAS structures in the PDB (http://dunbrack.fccc.edu/rascore/).
Doing Global Citizenship
Authors:   , King Theresa , Kelly Kristy E
Published: August 2022

This dissertation is a phenomenological study of how American military spouses experience, give meaning to and navigate their shifting identities as a spouse of an active-duty military member, parents, as Americans, and as global citizens while living in Italy. Findings from 45 survey responses and 19 in-depth interviews completed in 2021, at the height of the COVID-19 pandemic, reveal how military spouses experience these different identities, often in tension with each other. These tensions are exacerbated during a pandemic. These identity tensions cannot be defined as a linear relationship. If a military spouse relates strongly with one identity it may create a stronger tension with another identity due to the overseas environment in which they find themselves, even if temporarily. For example, if a person identifies strongly as a military spouse, a tension may arise if they identify as a global citizen; or if a spouse identifies strongly as an American worker, a tension may arise when they are forced to identify as a military spouse. If they strongly identify as a global citizen, they may experience a tension identifying as an American. When these tensions are situated during a global pandemic, the identities can become further complicated. Some military spouses may begin new global citizen practices, although they may not realize this is taking place. Others may resist change and stand firm within a singular identity space that helps them feel safe.
Interpretation Problems Relating the Scope of Meaning of the Term “Person Single-Handedly Raising Child” in the Polish Law
Authors: Bobrus-Nowińska Ewelina
Published: August 2022

Until the end of 2021, in accordance with the Act on Personal Income Tax (PIT Act), persons single-handedly raising children  benefited from joint taxation with a child, while as of the beginning of 2022, they are entitled to the tax relief of PLN 1500. After growing criticism of the recent amendment to the act, our government decided to return to the former legal status.  The aforementioned tax advantage, while being of great practical importance, raised and will continue to raise several doubts after the amendment. One of the most important issues is the precise definition of who is a “single parent” – whether this criterion is met when a child lives with one parent, but contacts the other parent and spends time with him or her occasionally, or when divorced parents have joint custody of a child. The Polish Deal (Polski Ład) partially addresses these doubts, but obviously does not dispel all of them.
Smart Shopping Cart for Visually Impaired Individuals
Authors: Shete Vikram , Shaikh Ariz , Sawant Rhea , Singh Chetna , P Sridevi Ponmalar , R Harikrishnan
Published: August 2022

Vision is one of our most important tools to help us survive in the world. Not being able to see well or at all is only the tip of the iceberg that people who are visually impaired have to deal with. Along with that, comes a whole new set of societal challenges, stigma, fears, and beliefs making these groups a minority and not shedding enough light on issues that they face is more common than we realize. While everyone in today’s world chases the buzzwords artificial intelligence and robotics to create complex technologies to solve problems like the mundaneness of a task, it would be incorrect to forget about the bigger picture that hints at helping mankind save the rest of it. The visually impaired face a variety of issues right from not being able to navigate along a path to the very basic grocery shopping at a shopping mall. This paper proposes an idea of a smart shopping cart that assists the visually impaired to navigate through various isles of a shopping mart and help them purchase the items they wish to buy with the help of braille assisted buttons and haptic feedback control without feeling the need for any human assistance.
Detection of Porcine DNA in Burger Products Using Real Time-Polymerase Chain Reaction (RT-PCR)
Authors: Roswiem Anna Priangani , Suseno Dedy , Septiani Triayu
Published: August 2022

Burgers are one of the processed meat products currently being traded in Indonesia to the suburbs and even to the villages. The raw materials for burgers are beef, chicken, fish, and pork. Until now, the price of beef is still costly for many customers. However, it turns out that many burger producers sell their products at very low prices. This condition raises suspicion from consumers that the producers mix or replace the beef with pork. Based on this issue, this study aims to examine the content of pork (porcine DNA) in burger products sold in traditional markets in Jakarta and frozen food outlets in the villages around Jakarta. Pig DNA testing used the Real-Time Polymerase Chain Reaction (RT-PCR) method. The results showed that porcine DNA was not detected in all the test samples (10 samples) from different brands, including those with the MUI halal logo.
Porcine DNA in Medicine toward Postpartum Patients from Medical and Islamic Perspectives in Malaysia
Authors: Binti Mod Ali Siti Nur Syahadah , Gunardi Setiyawan
Published: August 2022

Nowadays, the issue of the use of pig resources in medicine is a disputed Halal and Haram study. The widespread social media exposure of medicines containing pork in Malaysia has raised concern among many people, especially postpartum patients, who often be provided with pork-based medicine to prevent blood clots in the body. Most Malaysians still do not know the real action to take when faced with such a scenario. Thus, this study focuses on the purpose and requirements in using porcine DNA in postpartum patients according to the perspective of Medicine and Islam in Malaysia. This research methodology used qualitative methods through a library research approach by reviewing selected articles and interviews with physicians and Fiqh. The data collected were analyzed based on the principles of Maqasid Al-Shariah and Dharurah. By applying the principle “al-Darurat Tubih al-Mahzurat”, the results found that porcine DNA in medicine are allowed to use toward postpartum patients in Dharurat when there is no other option other than using drugs from haram sources.
Effect of Piracetam on Brain Oxidative Stress and Tissue Damage Following Toluene Exposure in Rats
Authors: Salam Omar M.E. Abdel- , El-Shamarka Marawa El-Sayed , Hassan Nabila S. , Abouelfadl Dalia M.
Published: August 2022

In this study, the effect of the nootropic drug piracetam on brain oxidative stress and histopathological changes in brain, liver and kidney following exposure to toluene in rats was examined. Piracetam (150 or 300 mg/kg, subcutaneously, daily) was given along with toluene (500 mg/kg, intraperitoneally, daily) for one week. The brain content of malondialdehyde (MDA), reduced glutathione (GSH) and the activity of paraoxonase-1 (PON-1), and butyrylcholinesterase (BChE) in brain homogenates were determined. Histopathology of the brain, liver and kidney and brain Bax immunohistochemistry were performed. Results showed that exposure to toluene resulted in increased brain lipid peroxidation (MDA) and NO along with decreased reduced glutathione. Toluene also inhibited PON-1, and BChE activities. The administration of piracetam had no significant effect on brain lipid peroxidation. The level of reduced glutathione was unchanged by piracetam but PON1 activity was increased by the lower dose of the drug. Piracetam showed no significant effect on BChE activity in toluene treated rats. Histopathological examination of the brain of toluene only treated rats showed degenerated neurons in cerebral cortex, marked neuronal vacuolation in hippocampus and focal hemorrhage. Bax 3 immunohistochemical staining showed cytoplasmic reactivity in degenerated neurons. Rats given piracetam showed decreased cortical cellularity, increased number of degenerated neurons and increased BAX staining. The higher dose of the drug caused sinusoidal hemorrhage and intertubular hemorrhage in kidney. Collectively, these results indicate that treatment with piracetam wan not able to decrease neuronal damage in rats exposed to toluene.
CONSTRUÇÃO DA AUTONOMIA DA MULHER PARA PREVENÇÃO DO CÂNCER DE MAMA
Authors: Viegas Aline da Costa , Muniz Rosani Manfrin , Zillmer Juliana Graciela Vestena , Dos Santos Bianca Pozza , Cardoso Daniela Habekost , Do Amaral Débora Eduarda Duarte
Published: August 2022

Objetivos: Compreender a construção da autonomia da mulher para prevenir o câncer de mama. Métodos: estudo qualitativo, interpretativo, pautado no conceito de autonomia de Paulo Freire. Foi realizado com 20 mulheres que frequentavam uma Unidade Saúde da Família de um município no Rio Grande do Sul, nos meses de junho a outubro de 2016. Resultados: o saber sobre a prevenção do câncer de mama, o protagonismo em busca do cuidado mamário está relacionado com as práticas autônomas das mulheres, os quais também estão circunscritos ao conhecimento popular e científico. Todavia, a curiosidade domesticada e a memorização mecânica das práticas preventivas também foram evidenciadas. Conclusões: entende-se que as ações e os projetos terapêuticos para a prevenção e detecção precoce do câncer de mama, compartilhados com as mulheres, necessitam favorecer ao protagonismo do cuidado de si. Dessa maneira, se faz necessário o respeito à autonomia da mulher usuária dos serviços de saúde.PALAVRAS-CHAVES: Prevenção de Doenças; Saúde da Mulher; Neoplasias da Mama; Autonomia Pessoal
PERFIL CLÍNICO-EPIDEMIOLÓGICO DE UM SERVIÇO DE ATENDIMENTO MÓVEL DE URGÊNCIA
Authors: Steindorff Gabriela Medeiros , Simon Bruna Sodré , Stamm Bruna , Garcia Raquel Pötter , Stofel Natália Sevilha , De Oliveira Júnior Sidnei Batista
Published: August 2022

Objetivo: Caracterizar o perfil clínico-epidemiológico do Serviço de Atendimento Móvel de Urgência de um município da Fronteira Oeste do Rio Grande do Sul/Brasil, referente à 2016 e 2017. Método: Estudo descritivo, documental retrospectivo e quantitativo. Incluíram-se 5.957 boletins de ocorrências de janeiro de 2016 até dezembro de 2017. Utilizou-se o SPSS 21.0, em que foram processadas as frequências relativas e absolutas. Resultados: Prevaleceram atendimentos por causa neurológica (11,9%) e colisão (14,3%). A maioria dos chamados foi para homens (55,7%) e a faixa etária de 60 a 79 anos (26,2%); prevaleceu o motivo de socorro (98,6%), unidade de suporte básico (57,3%) foi a mais utilizada. A maioria dos atendimentos não apresentou incidentes (90,1%). Conclusão: Os atendimentos mais prevalentes foram de causas neurológicas e as colisões. Homens e idosos foi a população mais atendida. Os atendimentos foram realizados em sua maioria pela unidade de suporte básico, prevalecendo a não ocorrência de incidentes.
Effect of L-arginine and Eugenol on Ram Semen Kinematic Parameters and Post Thawed Fertility Rate after Trans-cervical Artificial Insemination
Authors: Berean D. , Blaga-Petrean A. , Bogdan I. , Bogdan S. , Tamas-Krumpe O.M. , Cimpean R. , Pall E. , Nap M.E. , Bogdan L.M.
Published: August 2022

Backgroung: Long term storage of spermatozoa is one of the most desirable tools of assisted reproductive technologies. The purpose of this research was to evaluate the effect of two antioxidants on sperm kinematic parameters after the freezing-thawing process and the post thawed fertility rate after the trans cervical artificial insemination. Methods: Ejaculates from Lacune rams were collected using artificial vagina, were pooled and diluted using based extender (Biladyl, Minitube) and based extender with antioxidants (Eugenol, Arginine). Trans-cervical artificial insemination was performed with frozen seminal material in straws. Result: No significant differences were observed in samples cryopreserved in a base extender and in the base extender supplemented with Arginine. In Eugenol supplemented extender the kinematic parameters were significantly higher for p=0.5 (30.15% progressive motility after thawing) than in the others groups (23.57%, 24.38%). The fertility rate was higher for the straws conserved in extender supplemented with Eugenol (80%) compared with the base extender (55.55%) and the base extender supplemented with Arginine (60%).
Culturally Responsive Teaching in Nursing Education: A Faculty Development Project
Authors: Leibold Nancyruth , Schwarz Laura M. , Gordon Dawn
Published: August 2022

Culturally responsive teaching is a vital skill for nurse educators. A diverse nursing workforce is needed in the US to represent the population's demographics. Recruiting, retaining, and engaging a diverse student body is critical to addressing issues of disparities and cultural sensitivity in health care. In a project to promote success among diverse nursing students, nurse educators collaborated to create and present faculty development programs to build culturally responsive teaching skills. This article includes examples of culturally responsive teaching and describes the project and the faculty development curriculum and teaching materials produced.