bluuebunny/crossref_metadata_2025 huggingface dataset:
Advancing Public Organizations in Palestine through Collaborative Public Management Programs: An Empirical Investigation
Authors: Al-Ramlawi Doaa
Published: July 2024

Meningkatkan institusi publik di Palestina memerlukan kolaborasi, dimana program manajemen publik kolaboratif memainkan peran penting dalam menerapkan model perencanaan berkinerja tinggi di setiap organisasi. Artikel ini mengeksplorasi pendekatan ini secara menyeluruh, menjelaskan penerima manfaat dan pengaruhnya terhadap institusi. Studi ini mengacu pada tinjauan komprehensif literatur yang ada dan mengevaluasi studi sebelumnya untuk memberikan pemahaman yang berbeda tentang subjek tersebut. Penelitian ini berupaya mengevaluasi efektivitas program manajemen publik kolaboratif dalam mendorong perkembangan organisasi publik di Palestina. Dengan menggunakan pendekatan kualitatif dalam metodologi penelitian, kami bertujuan untuk memperjelas kerangka dan desain penelitian, menawarkan wawasan dalam membangun kembali dan mereformasi infrastruktur lembaga-lembaga publik di Palestina untuk kemajuan dan pembangunan, serta meningkatkan pemberian layanan. Temuan ini menggarisbawahi manfaat reformasi dan pengembangan sektor publik di Palestina, dengan tujuan mencapai efisiensi, keandalan, transparansi, dan peningkatan layanan, sekaligus menghilangkan korupsi dan nepotisme. Nilai penelitian ini terletak pada perlunya para peneliti mengatasi kesenjangan yang menghambat pembentukan program restorasi dan reformasi lembaga-lembaga publik Palestina. Dukungan harus diperluas untuk mendukung upaya mereka dalam menciptakan sektor kelembagaan yang bercirikan kredibilitas, keandalan, efisiensi, transparansi, dan layanan yang tepat, sekaligus meminimalkan penyuapan dan eksploitasi.
The Role of Teacher Commitment and Teacher Mentality on Principal Managerial by Teacher Health at Cilegon City
Authors: Sudiyono Rahmat , Yusuf Furtasan Ali , Hardianto Ade Manggala
Published: July 2024

Manajerial kepala sekolah merupakan kemampuan kepala sekolah mendorong komitmen guru dan kesehatan guru ke arah yang lebih baik. Tujuan penelitian adalah untuk mendesain ulang manajerial kepala sekolah dengan teori agensi. Desain penelitian adalah positivime kuantitatif. Populasi penelitian adalah seluruh guru Sekolah Dasar kota Cilegon. Teknik sampling menggunakan Teknik random (acak) sebanyak 157 responden. Teknik pengumpulan data dengan kuesioner digital yang disebar melalui grup PGRI kota Cilegon. Alat analisis menggunakan alat statistic Structural equation Model (SEM). Hasil penelitian antara lain: komitmen guru (p-value 0.000 < 0.05) dan kesehatan guru memiliki pengaruh positif signifikan terhadap manajerial kepala sekolah (p-Value 0.010 < 0.05), dan komitmen guru memiliki pengaruh positif signifikan terhadap kesehatan (p-Value 0.000 < 0.05). simpulan penelitian ini yaitu manajerial menggambarkan kompetensi, kinerja yang dapat diukur dengan komitmen guru dan kesehatan guru.
Need Analysis of The E-Module Development for Endocrinology Courses in Bioloy Department Students
Authors: Anggraini Atika , Yusal Yulianti
Published: July 2024

Hasil belajar mahasiswa banyak yang rendah, oleh karen itu berdasarkan hasil observasi ditemukan bahwa mahasiswa membutuhkan sumber belajar yang meningkatkan hasil belajarnya. Penelitian yang dilakukan bertujuan untuk mengetahui kebutuhan mahasiswa berupa sumber belajar pada mata kuliah endokrinologi. Analisis kebutuhan dilakukan berdasarkan tahapan pertama dari model ADDIE yaitu Analisis. Metode penelitian yang digunakan adalah deskriptif kualitatif.Subjek penelitian ini adalah mahasiswa program studi Biologi. Sampel dipilih bagi yang pemintaan Kesehatan.Kuesioner diberikan kepada mahasiswa yang telah mengambil mata kuliah endokrinologi dan dosen endokrinologi. Hasil analisis angket dosen dan mahasiswa menunjukkan bahwa mahasiswa memerlukan bahan ajar tambahan berupa e-modul berbasis penelitian yang memuat contoh-contoh kontekstual. Hal ini, dapat disimpulkan bahwa mahasiswa Biologi belum memiliki bahan ajar e-modul berbasis penelitian yang memuat contoh konkrit/kontekstual, sehingga perlu dikembangkan sumber belajar berupa e-modul.
The Influence of Diversity Product, Tagline, and Store Atmosphere on Impulsive Buying Through Positive Emotion as A Mediation Variable (Study on Gen Z and Millennial Customers of Mr. DIY Products in Malang)
Authors: Ni'mah Ziadatun , Hasan Irmayanti
Published: July 2024

Pada Era Society 5.0 dengan berbagai macam jenis usaha maupun produk yang dihasilkan, menyebabkan timbulnya sikap konsumtif dalam diri manusia. Jenis penelitian ini yaitu kuantitatif dengan menggunakan teori model Hawkins Stern atau yang lebih dikenal sebagai impulsive buying theory. Adapun sampel dalam penelitian ini yaitu berjumlah 210 responden sesuai dengan perhitungan rumus hair et al. Teknik pengambilan sampel pada penelitian ini menggunakan metode Non-Probability Sampling melalui Purposive Sampling. Data penelitian ini diolah dengan menggunakan analisis data statistik deskriptif dan metode Structural Equation Model (SEM) melalui program software PLS 3.0. Hasil penelitian menunjukkan bahwa: 1) Diversity product tidak berpengaruh signifikan terhadap impulsive buying. 2) Tagline berpengaruh signifikan terhadap impulsive buying. 3) Store atmosphere tidak berpengaruh signifikan terhadap impulsive buying. 4) Positive emotion berpengaruh signifikan terhadap impulsive buying. 5) Positive emotion mampu memediasi diversity product terhadap impulsive buying. 6) Positive emotion mampu memediasi tagline terhadap impulsive buying. 7) Positive emotion mampu memediasi store atmosphere terhadap impulsive buying.
Islamic Content as A Syiar of Religious Moderation on Social Media in Building Peaceful and Tolerant Religious Harmonization of Religions
Authors: Sutrisno Edy , Fanani Ahmad , Kartikaningsih Yeni , Akhiroh Mazro’atul , Rochim Abdul
Published: July 2024

Seiring dengan perkembangan teknologi dan informasi perbedaan sikap dan pandangan juga membawa dampak yang luas pada arus globalisasi yang multi dimensi, narasi-narasi konservatif di media sosial seperti sikap intoleransi, ekstrimisme, dan bahkan radikalisme dalam beragama juga menghiasi dimedia sosial, bahkan dominasi konten intoleran lebih banyak dari pada konten yang toleran. Tujuan dari penulisan ini adalah untuk mendeskripsikan konten Islami sebagai syiar moderasi beragama di media sosial dalam membangun harmonisasi umat beragama yang damai dan toleran. Metode yang digunakan dalam penulisan ini dengan metode kualitatif menggunakan pendekatan library research. Adapun hasil dalam penelitian ini; Pertama, memperbanyak konten bermuatan moderasi beragama dengan menampilkan Islam sebagai agama yang humanis, merubah paradigma dari fanatisme menuju keterbukaan dan memperkuat Islam dengan pemahaman secara komprehensif. Kedua, Diperlukan upaya dan semangat dalam menyemarakkan gaung moderasi di media sosial melalui peran berbagai pihak, diantaranya dengan mengedepankan kebijakan politik dari pemerintah, juga lembaga keagamaan, tokoh-tokoh penting, serta elemen lain yang mempunyai pengaruh besar. Ketiga, menyaring dan bijak dalam penggunakan media sosial dalam mengekpresikannya terutama peran serta masyarakat dalam memperkuat penyebaran konten paham moderasi beragama.
Pengembangan Produk Wisata Berbasis Pengalaman di Desa Wisata Rammang-Rammang Menggunakan Model Bisnis Canva
Authors: Rahayu Mia , Machmury Andri , Eppang Buntu Marannu , Renold Renold
Published: July 2024

Penelitian ini dilakukan di Desa Wisata Rammang-rammang, Kabupaten Maros. Penelitian ini bertujuan untuk meningkatkan keterampilan masyarakat lokal mengembangkan produk wisata. Jenis penelitian menggunakan penelitian dan pengembangan (R & D). Tahapan penelitian mulai dari identifikasi lapangan, observasi, wawancara, focus group discussion, desain produk, uji coba  hingga desiminasi. Uji coba dialkukan pada kelompok kecil dan kelompok besar. Hasil penelitian yaitu produk wisata berupa 1) Paket wisata yang memuat konten story telling fenomena fisik dan budaya setempat, 2) Rute Walking Tour dengan model Chaining Loop,3)  Pemanfataan homestay dan kuliner lokal serta produk pengembangan diimplementasikan menggunakan Model Canva untuk kegiatan promosi dan tata kelola bisnis pariwiwisata.  Rekomendasi untuk penelitian di masa yang akan datang untuk melakukan uji coba pada kelompok yang lebih besar lagi serta diperlukan pengembangan paket wisata yang sarat pengalaman di seluruh kawasan Geopark Maros-Pangkep.
Survei Literasi Ekonomi Digital Mahasiswa Akuntansi
Authors: Sosrowidigdo Suryanto
Published: July 2024

Untuk memperbaiki kendala ekonomi, sosial, dan ekologi di suatu negara diperlukan literasi tentang ekonomi digital yang berkelanjutan, sehingga literasi ekonomi digital menjadi suatu keharusan yang perlu dikuasi oleh mahasiswa bidang akuntansi. Tujuan penelitian ini adalah untuk mengetahui gambaran literasi tentang ekonomi digital bagi mahasiswa yang telah mempelajari kajian tentang ekonomi atau pun keuangan. Penelitian menerapkan metode survei, meliputi responden penelitian ini adalah 40 mahasiswa semester 4, 6, dan 8 pada program studi akuntansi di salah satu perguruan tinggi swasta di Jawa Tengah. Pengumpulan data dalam penelitian ini dilakukan dengan menggunakan angket yang terdiri dari 5 indikator untuk mengukur literasi pembayaran digital pada mahasiswa. Kuesioner ini memiliki 25 pertanyaan, dimana masing-masing indikator memiliki 5 butir pertanyaan. Hasil penelitian menunjukkan bahwa responden telah mengetahui adanya pembayaran secara digital/non tunai dan telah mengetahui aplikasi-aplikasi yang dapat digunakan untuk melakukan transaksi digital.
Jumlah Produk Terjual: Live Events dan Kualitas Produk Melalui Pembelian Implusif
Authors: Windarko Windarko , Wahyuningjati Tri , Sabrina Afiifah Nur
Published: July 2024

Tiktok, sebuah platform media sosial yang populer saat ini dan telah menjadi bagian tak terpisahkan dari kehidupan sehari-hari, memengaruhi cara orang berinteraksi, berbagi, dan mengonsumsi konten. Tujuan Penelitian ini adalah men\yelidiki hubungan antara kuantitas produk yang terjual selama Live Events TikTok dan kualitas produk melalui perilaku pembelian implusif. Hasil Penelitian ini menunjukkan bahwa ketiga faktor tersebut secara positif memengaruhi produk terjual, dengan kualitas produk sebagai faktor dominan, Meskipun pembelian implusif memainkan peran penting, produk terjual lebih dipengaruhi oleh kualitas produk dibandingkan perilaku pembelian implusif. Metode Penelitian ini adalah menggunakan teknik analisis SEM-PLS dengan bantuan alat pengolah data SmartPLS versi 4. Kesimpulannya, penawaran diskon pada produk dapat memicu pembelian spontan dan meningkatkan penjualan.
Rapid detection of microplastics in feed using near-infrared spectroscopy
Authors: Masoero Giorgio , Barbera Salvatore , Kaihara Hatsumi , Mabrouki Sabah , Glorio Patrucco Sara , Abid Khalil , Tassone Sonia
Published: July 2024

The presence of microplastics in the forage and feedstuffs of domestic animals represents an imminent threat to the entire food chain that may reach humans since the particles could be transferred into the intestinal barriers and contaminate blood and animal products. Until now, there is no simple, rapid, sustainable, and reliable method to detect microplastics in animal feed. The objective of this study was to investigate the ability of near-infrared spectroscopy (NIRS) to detect microplastics in ruminant feeds. Two types of instruments were tested using four feeds (corn silage, mixed hay, rye grass silage, soybean meal) and a total mixed ration. Two types of crumbled contaminants, low-density polyethylene and polystyrene, were accurately mixed at ratios of 0, 1, 3, and 5 mg g-1. The pool of the five matrices examined by the benchmark instrument (714-3333 nm) yielded an accuracy of approximately 0.8 mg g-1 and a detection limit of about 1 mg g-1, however, the errors could be halved in separate calibrations. A short wavelength range (714-1070 nm) or a smart NIRS instrument proved an acceptable discrimination of the concentrations. Following these preliminary results, any validation on other samples with different and powerful NIRS tools is encouraged.
Developing a quantitative multimodal and multi-scale, fully non-destructive technique for the study of iron archaeological artefacts
Authors: Granget Elodie , Cocen Ocson , Shakooriokooie Mahdieh , Zhan Qianru , Lumongsod-Thompson Marian Nida , Kaestner Anders , Mannes David , Brambilla Laura
Published: July 2024

This article presents the methodology and initial findings of the SNSF Sinergia project CORINT. The project's objective is to elucidate the corrosion mechanisms affecting iron-based structures entrapped in various porous media. This paper focuses specifically on iron archaeological artefacts (IAAs) in soil. A novel multimodal quantitative imaging technique, which integrates neutron and X-ray computed tomography (NX-CT), is under development for non-destructive examination of corrosion processes. The method involves registering and fusing neutron and X-ray tomography data, followed by Gaussian mixture model (GMM) clustering for phase segmentation. Imaging was conducted on two IAAs, Vrac C and BdC1. Additionally, random cross-sections of these samples underwent analysis through optical microscopy, µRaman spectroscopy, and SEM-EDS to characterize and correlate corrosion layers with NX-CT results. This study yields valuable insights into the corrosion of IAAs, enabling the non-destructive investigation of corrosion processes in porous media. The implications extend beyond the preservation of cultural heritage, to the examination of long-term corrosion behaviors in contemporary iron structures, steel within concrete, and nuclear waste disposal plans.
Multi Organ Failure (MOF) and a Promising Novel Device
Authors:   Department of Nuclear Medicine and Molecular Imaging, Neurospinal & Medical Institute, Karachi, Pakistan., Kamal Shahid
Published: July 2024

Acutely ill hospitalized patients are at risk of cascading failure of vital organs leading to prolonged stay in the hospital, persistent dysfunction of vital organs and higher probability of death. It is estimated that 50 to 75% of ICU patients have failure of one or more vital organs and as more organs are involved the risk of death increases [1, 2]. For example in Acute on Chronic Liver Failure (AOCLF) the 28 day probability of death increases from 20% with one vital organ failure to 90% or higher if 3 or more organs are involved. Dysfunction of brain, lungs, heart and kidneys are most commonly seen, kidney involvement is usually poor prognostic sign.
Comparison of Mean Hospital Stay after Nebulization with 3% Hypertonic Saline vs Salbutamol in Treatment of Bronchiolitis
Authors:   Department of Pediatric Medicine, University of Child Health Sciences, Lahore, Pakistan., Nizam Rabia , Khalid Amna ,   King Edward Medical University, Lahore, Pakistan., Shafique Mehwish ,   Department of Pediatric Medicine, University of Child Health Sciences, Lahore, Pakistan., Imtiaz Mehwish ,   Department of Pediatric Gastroenterology and Hepatology, Pakistan Kidney and Liver Institute, Lahore, Pakistan., Masood Shadab ,   Department of Pediatric Medicine, University of Child Health Sciences, Lahore, Pakistan., Masood Muhammad Khalid ,   Department of Pediatric Medicine, University of Child Health Sciences, Lahore, Pakistan.
Published: July 2024

Abstract: Background: With an estimated prevalence of 33% in children age >2years and owing to 1 in 10th cause of hospitalization in children, Bronchiolitis is a major factor for morbidity and mortality. Varying nebulization doses have been shown to produce different clinical outcomes in patients with bronchiolitis. Objective: To compare mean hospital stay after nebulization with 3% hypertonic saline compared to the salbutamol among patients of bronchiolitis Materials and Methods: This was a randomized control study done at pediatric medicine ward, Services Hospital, Lahore. The study was done during 8th May 2018 to 8th November 2018. Data was collected from 68 children of age >3 months to < 2 years of both genders i.e. (34 in each group) fulfilling inclusion criteria. SPSS software was used for data entry and analysis. For quantitative variables age, mean and standard deviation were used whereas for qualitative variables like gender, frequency and percentages were used. Independent sample t-test was used for comparing mean hospital stay among the two groups taking p-value<0.05 as significant. Result: Average age in Salbutamol group was 1.06 ± 0.50 years and in Hypertonic solution mean age was 1.24 ± 0.55 years. There was significant difference in mean hospital stay with relatively lesser in hypertonic solution vs the Salbutamol group [3.18 ± 1.11 vs 4.44 ± 1.08 ; p-value <0.001]. Upon post-stratification analysis, the mean hospital stay was found to be significantly lower in the Hypertonic group vs. Salbutamol group with respect to age, gender and the duration of the disease (p-values<0.05 for all). Conclusion: This study concludes that the mean hospital stay was statistically lower in the hypertonic solution group vs the Salbutamol group. Moreover, the clinical efficacy of the hypertonic saline can be utilized in future to gain early recovery of Bronchiolitis and hence it can reduce the hospital stay and related cost. Keywords: Bronchiolitis, Salbutamol, Hypertonic saline, Hospital stay, Severity, Duration, Treatment.
Evaluation of ChatGPT’s Performance in Making-Decision of Dialysis in Acute Kidney Injury
Authors: Can Başak , Kahvecioğlu Esra Deniz , Palıt Fatih , Küçük Mehmet , Karaali Zeynep
Published: July 2024

Purpose
To evaluate the performance of ChatGPT in identifying patients in need of dialysis.
Methods
A total of 100 patients who presented with acute kidney injury and were treated with dialysis and without dialysis at the internal medicine clinic were retrospectively reviewed. Patient histories that included age, gender, comorbidities, blood pressure, body volume status, uremic symptom status, urine output status, and blood gas analysis, as well as measurements of urea and creatinine levels were created. These patient histories were inputted into the free version of ChatGPT 3.5, and we requested a clinical evaluation of the patients along with recommendations categorizing them as low, medium, or high risk for dialysis treatment. The responses from ChatGPT were compared with the actual dialysis status of the patients. Additionally, ChatGPT responses were evaluated and scored by two nephrologists who were unaware of the dialysis status.
Results
The sensitivity of ChatGPT in recommending patients' need for dialysis was calculated as 94%, 97% and 97% for ChatGPT 1, 2 and 3 answers, respectively. Specificity for ChatGPT responses 1, 2, and 3 was calculated as 81%, 76%, and 78%, respectively. (p<0.001) The mean clinical evaluation scores were 4.71 ± 0.4 and 4.67 ± 0.4, and treatment recommendation scores were 4.45 ± 0.7 and 4.39 ± 0.7 for Nephrologist 1 and Nephrologist 2. (p=0.002) (p<0.001) (respectively)
Conclusion
ChatGPT can be used as a decision support tool to identify patients who may need dialysis. Nevertheless, healthcare professionals should remain a step of the decision-making process at present.
Does Economic Policy Uncertainty, Nuclear Energy, and Crude oil influence CO2 Emissions? A sectoral growth analysis on G20 countries
Authors: Mohanty Seba , Dash Sarthak , Priyadarshini Sugyanta , Dulla Nisrutha , Swain Sukanta Chandra
Published: July 2024

The G20 nations collectively accounted for a significant portion of global CO2 emissions due to their vast economies and rising energy demand. While some G20 nations have made substantial efforts to reduce their emissions through policies such as renewable energy incentives and carbon pricing, others may still heavily rely on fossil fuels for energy production and industrial processes. Therefore, this recent study endeavored to investigate the relationship between nuclear energy consumption (NEC), crude oil (CO), and Economic Policy uncertainty (EPU) with CO2 emissions in three economic sectors of G20 nations. Despite voluminous research work conducted on mitigating CO2 emission, To the best of our understanding, this paper marks the inaugural endeavor to investigate the impact of the afore-mentioned variables in three-sector-model with emission across G20 countries. To achieve this objective, we carried out a range of examinations, encompassing panel unit root and cointegration tests, followed by panel DOLS, ARDL, and the Dumitrescu-Hurlin causality test, spanning the period from 1990–2022. The panel ARDL results indicate that while CO increases carbon emissions in the short term, NEC decreases them. In terms of the synergy between NEC and EPU, it's noteworthy to mention that the collective impact of increase in NEC and decrease in EPU reduces the emission in three-sectors. Nevertheless, in the long term, EPU exhibits a negative correlation with emissions across three sectors. Hence, the current research proposes waning EPU as a deliberate strategy to reduce emissions under careful consideration of its potential effects and feasibility within broader economic and policy contexts.
InstructPLM: Aligning Protein Language Models to Follow Protein Structure Instructions
Authors: Qiu Jiezhong , Xu Junde , Hu Jie , Cao Hanqun , Hou Liya , Gao Zijun , Zhou Xinyi , Li Anni , Li Xiujuan , Cui Bin , Yang Fei , Peng Shuang , Sun Ning , Wang Fangyu , Pan Aimin , Tang Jie , Ye Jieping , Lin Junyang , Tang Jin , Huang Xingxu , Heng Pheng Ann , Chen Guangyong
Published: July 2024

Large language models are renowned for their efficacy in capturing intricate patterns, including co-evolutionary relationships, and underlying protein languages. However, current methodologies often fall short in illustrating the emergence of genomic insertions, duplications, and insertion/deletions (indels), which account for approximately 14% of human pathogenic mutations. Given that structure dictates function, mutated proteins with similar structures are more likely to persist throughout biological evolution. Motivated by this, we leverage cross-modality alignment and instruction fine-tuning techniques inspired by large language models to align a generative protein language model with protein structure instructions. Specifically, we present a method for generating variable-length and diverse proteins to explore and simulate the complex evolution of life, thereby expanding the repertoire of options for protein engineering. Our proposed protein LM-based approach, InstructPLM, demonstrates significant performance enhancements both in silico and in vitro. On native protein backbones, it achieves a perplexity of 2.68 and a sequence recovery rate of 57.51, surpassing ProteinMPNN by 39.2% and 25.1%, respectively. Furthermore, we validate the efficacy of our model by redesigning PETase and L-MDH. For PETase, all fifteen designed variable-length PETase exhibit depolymerization activity, with eleven surpassing the activity levels of the wild type. Regarding L-MDH, an enzyme lacking an experimentally determined structure, InstructPLM is able to design functional enzymes with an AF2-predicted structure. Code and model weights of InstructPLM are publicly available.
Differentiation of newly developed intracranial lesions after long-term management of non-germinomatous germ cell tumors (NGGCTs)
Authors: Zheng Xue-Qing , You Hui , Lian Xin , Mao Xin-Xin , Huang Huai-Gu , Wang Xi , Liu Jia-Hui , Duan Lian , Zhu Hui-Juan
Published: July 2024

Intracranial germ cell tumor (iGCT) is a rare type of brain tumors which is prevalent among children and adolescents. Among iGCTs, non-germinomatous germ cell tumors (NGGCTs) presented with a poorer prognosis. Since treatment primarily involves chemotherapy and radiotherapy, it is crucial to differentiate treatment-related secondary tumors that may develop during follow-up from recurrences of iGCTs. However, there are few studies distinguishing between these two outcomes. Based on the criteria from SIOP trials, we identified 3 NGGCT patients from Peking Union Medical College Hospital (PUMCH) who achieved remission after initial treatment but developed new intracranial lesions upon long-term follow-up. We retrospectively analyzed the clinical characteristics, treatment, and prognosis of these 3 patients. At first, all 3 NGGCT patients presented with elevated tumor markers and intracranial lesions on MRI. After the initial treatment, all patients achieved clinical remission and were followed-up regularly. However, more than 5 years later, new intracranial lesions appeared on MRI in these 3 patients, with variated locations and changes in tumor markers. 1 patient was diagnosed with secondary meningioma, while the others were highly suspected as recurrences of iGCTs. All patients received timely and appropriate interventions. In conclusion, differentiating between tumor recurrence and secondary tumors during the follow-up of iGCTs requires a comprehensive assessment involving tumor marker patterns, imaging features, and pathological findings.
The Impact of Meta-linguistic Ability on Mathematical Ability: Evidence from Phenotype and Genetics
Authors: Zhao Jingjing , Zhang Ximiao , Yang Qing
Published: July 2024

Despite the importance of language and mathematical abilities in children's development, there is still a lack of systematic empirical research on how language skills affect mathematical skills. There are two main theories that focus on the relationship between language and mathematical ability: the thinking function hypothesis and the medium function hypothesis. Based on the two hypotheses, the present study investigates the impact of meta-linguistic abilities on mathematical abilities among Chinese language users from quantitative traits and genetic level. Results showed that phonological awareness, morpheme awareness, rapid automatize naming, and orthographic awareness all have an impact on arithmetic ability, mathematical reasoning ability, and visual spatial ability both directly and by means of decoding ability after controlling for performance IQ, sex and age. Polygenic scoring for language abilities were found to be able to predict arithmetic and mathematical reasoning abilities rather than visual spatial abilities. Indicating that the impact of meta-linguistic abilities on mathematical abilities is partly due to the mediating role of reading ability, and may also be due to the overlapping cognition basis between meta-linguistic abilities and basic computational ability. Our findings provide a deeper understanding of how meta-linguistic abilities impact mathematical abilities, offering valuable insights into the comorbidity of language and mathematical deficits.
Knowledge, Attitudes, And Practices Towards Sexually Transmitted Infections Among GOPD Patients in Ekiti State, Nigeria
Authors: Ashaolu Joseph Opeolu , Ashaolu Kehinde R. , Ogunbola Steven
Published: July 2024

Background
The burden of sexually transmitted infections (STIs) have become a serious global public health concern with consequence morbidity and mortality, especially in developing countries. The risk of contracting these infections however, spread amongst various subgroup of the population. This study aimed to comprehensively examine the knowledge, attitudes, and practices pertaining to sexually transmitted infections (STIs) among patients attending the General Outpatient Department (GOPD) at Ekiti State University Teaching Hospital (EKSUTH).
Method
A cross-sectional study surveyed 400 outpatients, aged 18 to 45 years old, from the General outpatient department (GOPD) in the health facility from November 2023 – February 2024. Community-based and descriptive approach was employed, utilizing a structured questionnaire to assess both the quantitative and qualitative indicators of knowledge, attitude and practices amongst the respondents. Chi-square and regression methods was employed in the analysis of the various factors and outcomes.
Results
Our result shows that socio-demographic characteristics such as gender and education level are key determinants of STI knowledge levels with a significant association (P < 0.05) between sex (χ2 = 22.71, p = 0.01), level of education (χ2 = 36.61, p = 0.01), occupation (χ2 = 33.45, p = 0.01) and Knowledge of STIs reported in this study. However, there were no significant differences based on age, marital status, or religion. From the data, majority of patients with positive attitudes 82.80% (n = 231) are willing to seek healthcare services compared to those with negative attitudes 16.20% (n = 48). In addition, a significant association was observed between attitudes of GOPD patients and health seeking behavior (p = 0.04), indicating the role of attitudes towards STIs in healthcare-seeking behavior among GOPD patients. Moreover, our result shows that cost of drugs (χ2 test = 35.15, df = 3, p = 0.002), impacts on privacy (χ2 test = 36.61, df = 3, p < 0.001), drug use inconveniences (χ2 test = 43.171, df = 3, p = 0.03) and trust in healthcare providers (χ2 test = 44.149, df = 3, p = 0.01) are all significantly associated with engaging STIs safety practices. Thus, attitudes towards STIs significantly impacted healthcare-seeking behaviour, underscoring the importance of positive attitudes in promoting proactive engagement with healthcare services.
Conclusion
These findings emphasizes the need for targeted health education interventions to address knowledge gaps, reduce stigma, and foster safe sexual practices among the population. Leveraging on these insights will enable healthcare providers and policymakers to collaboratively work towards mitigating the burden of STIs and enhancing sexual health outcomes within EKSUTH and similar healthcare settings.
Long-term inflammatory outcome after placement of a novel two-piece dental implant in a dog model experimental peri-implantitis
Authors: Chaushu Liat , Tal Haim
Published: July 2024

Purpose - Evaluate the inflammatory outcome of a two-piece novel titanium dental implant (test article) vs. a one- piece titanium dental implant (control article) inducing experimental peri-implantitis in a dog model.
Materials & Methods
A novel, two-piece pre-assembled implant with a 0.2-thickness sleeve in its coronal 4.2 mm part was developed (Test article). Ligature-induced experimental periimplantitis model was applied, followed by decontamination and bone grafting in seven dogs. Four groups were assessed according to decontamination and resurfacing protocol: E1 (Experimental 1): test article- sleeve removed, mechanical and chemical decontamination, new rough surface non-threaded sleeve was inserted; E2 (Experimental 2): test article- sleeve removed, mechanical and chemical decontamination, test article remained denuded presenting a turned non-threaded surface; C1 (Control 1): sleeve remained, mechanical and chemical decontamination in test article, original rough surface, non-threaded sleeve; C2 (Control 2): control article cleaning, mechanical and chemical decontamination of original rough surface, threaded implant. Buccolingual and mesiodistal sections were prepared for each site. Resin qualitative and semi-quantitative histopathologic inflammatory parameters were analyzed.
Results: Group C1 showed statistically significant highest signs of residual long-term inflammation, followed by groups E1, and C2. Group E2 displayed the lowest local inflammation. Mesio/Distal aspects displayed increased long-term inflammatory infiltrate albeit not statistically significant.
Conclusions
Within the limits of the present study, it may be concluded that – 1. The decontamination procedure is more effective in a commercial one-piece vs. a two-piece dental implant. 2. Mechanical and chemical decontamination outcome is insufficient. Resurfacing improves the decontamination outcome. 3. Decontamination of the turned surface is superior to the rough surface.
Clinical relevance: When choosing the most appropriate dental implant for individuals with a high risk for peri-implant disease, a one-piece dental implant with a turned crestal surface is preferable. Once occurring, the control of peri-implant disease inflammation may be more successful. Decontamination is usually not enough. Resurfacing is highly recommended if possible.
Development of a biocomposite based on cassava bagasse and fique fiber with potential use in the manufacture of pots: physical-mechanical characterization and biodegradability
Authors: Bolaños Pedro Alban , Buitron Elsa Susana Cajiao , Carlosama Diego España , Muñoz Ricardo Camacho , Castillo Hector Samuel Villada , Torres Gerardo Andrés
Published: July 2024

The objective of this study was to develop a biocomposite material from cassava bagasse and fique fiber with potential use in the manufacture of pots. The study began with the characterization of cassava bagasse and fique fiber, and then proceeded to obtain the composite material with its respective characterization. The fique fibers showed a water absorption of 55.78 ± 4.27 %, a tensile strength of 298.645 MPa, a modulus of elasticity of 5.3 GPa and an elongation of 11.47%, an aspect ratio between 10 and 50, a maximum peak degradation of 359 °C and a crystallinity of 63%. In the case of cassava bagasse, it showed a maximum degradation peak at 317°C. A crystallinity of 45.3% and the morphological study revealed a structure composed of small starch granules surrounded by cellulosic fibers. The composite material was obtained with a mixture of 35% fique fiber and 65% cassava bagasse gel. This biocomposite had low water absorption and high mechanical strength. FTIR analysis indicated that the band between 3200 cm-1 and 3700 cm-1 broadened slightly after the addition of fique fiber, which could be due to the formation of intermolecular hydrogen bonds between starch and fiber. In addition, the material was found to meet the biodegradability condition required by EN 13432.
Early autologous and/or allogeneic stem cell transplantation for adult patients with advanced stage T- lymphoblastic leukemia/lymphoma or Burkitt lymphoma. A retrospective single-centre analysis
Authors: Steiner Normann , Baier Katherina , Ritter Denise , Rudzki Jakob , Hetzenauer Gabriele , Köck Stefan , Kircher Brigitte , Gunsilius Eberhard , Wolf Dominik , Nachbaur David
Published: July 2024

Introduction: T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) and Burkitt lymphoma (BL) are uncommon, highly aggressive diseases originating either from immature precursor T cells or from mature B cells in BL.
Patients and Methods: We retrospectively analyzed the outcome of an early autologous and/or allogeneic stem cell transplantation (SCT) concept in 28 patients with advanced stage T-ALL/LBL and BL after three to four remission induction/consolidation chemotherapy cycles.
Results: Considering only patients in first complete remission (CR), the 5-year overall survival (OS) and event-free survival (EFS) was 91% in patients with BL and 73% in patients with T-ALL/LBL with a 5-year relapse incidence (RI) of 9% in patients with BL and 27% in patients with T-ALL/LBL. All relapsing patients finally succumbed to the disease (n=10) or complications/toxicity after having received a salvage allogeneic transplant (n=5).
Conclusion: Despite the low patient number our retrospective single-centre analysis by incorporating an early intensive high-dose chemo-/radiotherapy strategy with either autologous or allogeneic stem cell transplantation, although preliminary, show promising long-term outcome. Further studies are highly warranted to better define those patients who might benefit most from such a treatment approach.
Individuals’ food preferences can be influenced by the Music styles: An ERP study
Authors: Tian Dingyue , Xu Ziyuan , Yan Han , Tie Bijie , Zhao Wen , Jing Yuanluo , Pang Yazhi , Liu Xiaolin , Zhao Jia , Liu Yong
Published: July 2024

Studies have shown that there is a cross-modal association between listening to music and eating. This study aims to explore the influence of music style on individuals’ food preferences and provide evidence for understanding multi-sensory research. Twenty seven participants participated in the experiment. The experiment consisted of two parts. Firstly, participants completed basic information; and then completed the food choice task after being stimulated by four different styles of music and simultaneously recorded EEG data. The behavioural results showed that: compared with low-calorie foods, individuals selected more high-calorie foods. In addition, individuals selected more high-calorie foods than low-calorie foods during the jazz music; while individuals selected more low-calorie foods than high-calorie foods during the classical music. The ERP results showed that: The N1 amplitudes were smallest during the classical music and greatest during the rock music; the N450 amplitudes were smallest during the jazz music. P2 amplitudes were smallest during the rock music and greatest during the classical music. P3 amplitudes during jazz music were the greatest. Pearson analysis showed that body satisfaction was positively related to classical-P3, Jazz-P3 and Rock-P3; BMI was negatively correlated with body satisfaction. Our study provides innovative practical perspectives for healthy eating.
The lingual and facial arteries’ common origin: A systematic review with meta-analysis and a computed tomography angiography study
Authors: Triantafyllou George , Vassiou Katerina , Duparc Fabrice , Vlychou Marianna , Paschopoulos Ioannis , Tsakotos George , Tudose Razvan Costin , Rusu Mugurel Constantin , Piagkou Maria
Published: July 2024

Purpose
The present evidence-based systematic review with meta-analysis aimed to investigate the fusion morphology of the lingual artery and facial artery (in the form of the linguofacial trunk-LFT) pooled prevalence and morphometry. After carefully investigating the data literature, a retrospective computed tomography angiography (CTA) study was performed to investigate a few parameters that were not well-studied.
Materials:
An evidence-based systematic review retrieved 41 studies that met our inclusion criteria to identify the LFT pooled prevalence. The literature search was performed using PubMed, Google Scholar, Scopus, and Web of Sciences databases. Then, a meta-analysis of the literature was performed using the open-source R programming language and the RStudio software. Moreover, two hundred CTAs were randomly selected and retrospectively studied to identify LFT topography, morphology, and morphometry.
Results
The LFT pooled prevalence was calculated at 16.41%. The subgroup analyses for nationality, type of study, laterality, and gender retrieved no statistically significant association. The unilateral appearance was estimated at 15.92%, compared to the bilateral at 3.28% (p < 0.001). Concerning the findings of our original study, 50 LFTs were identified (12.5%) unilaterally in 34 patients and bilaterally in 8 patients. A significant correlation was observed between the distance LFT origin from the carotid bifurcation (CCB) (p < 0.001) and the distances LA and FA origin from the CCB (p = 0.004).
Conclusions
A systematic review with meta-analysis of the LFT were presented, along with an original imaging retrospective study investigating detailed parameters of LFT topography, morphology and morphometry. Knowledge of LFT presence is essential for interventionists in the head and neck region.
Polyacrylonitrile Fiber Recycled Concrete Frost Durability Test And Damage Modeling Study
Authors: Wang Rui , Shen Xiaolin , Deng Xianghui , Yang Yiwen , Zhang Jinzeng , Gao Xiaoyue
Published: July 2024

The recycling of concrete is environment-friendly and contributes to the sustainable development strategy. Recycled concrete can achieve better compressive strength, but there are deficiencies in tensile and frost durability. Then, the polyacrylonitrile fiber can be used as a toughening component due to its good properties such as high tensile strength, high ultimate elongation, etc., which can endow the recycled concrete with higher toughness and maintain the properties of concrete under the high altitude and cold conditions. In this study, mechanical tests and frost durability tests were conducted on polyacrylonitrile fiber recycled concrete with polyacrylonitrile fiber mixing content of 0.7 kg/m3, 0.8 kg/m3, 0.9 kg/m3 and recycled coarse aggregate’s substitution rates of 30%, 40%, and 50%. The results showed that the concrete with the best frost durability is the one with 40% replacement of recycled coarse aggregate and 0.8 kg/cm3 of polyacrylonitrile fiber. Based on the experimental research, a freeze-thaw damage model of polyacrylonitrile fiber recycled concrete was developed, revealing the damage mechanism of polyacrylonitrile fiber recycled concrete. The results are of great significance in theory and engineering for the application of recycled concrete.
Comparative study of three alcohol-related harm reduction programs: an ideal-type analysis
Authors: Perrin Sarah , Fillol Amandine , Stevens Nolwenn , Cambon Linda , Martin-Fernandez Judith
Published: July 2024

The present article aims to identify appropriate interventional levers based on different types of publics and professionals, by comparing three alcohol-related harm-reduction programs implemented in France. To offer a transversal and more relevant analysis for action, we carried out an analysis by ideal types based on typical profiles of users and professionals. Twenty-one professionals using one of the three interventions took part in this study, and twenty-one users were included. Three typical profiles for users have therefore been identified: the socially included drug user, using alcohol only not targeting abstinence, the multiple substance user in very precarious situation with an ambivalent attitude to their substance use, and the middle-class drug user who want to achieve abstinence and feels guilty. Four typical profiles for professionals have also been identified: the isolated leader, the leader of a group, the willing professional eager to improve their practices, and the professional overwhelmed by a failing system. Depending on the user's profile, certain levers and professional profiles appear to be particularly suitable for ensuring the effectiveness of the intervention and the user's adherence to the program. All our findings point to the need to adapt interventions to users' needs, rather than expecting users to adapt to the objectives of the interventions. Mobilization of the notion of proportionate universalism, as defined in 2010, could be a relevant perspective for AHR interventions.
Serum Creatinine as a Mediator in the Association Between Iron Status and Cardiovascular Disease Among Menopausal Women: A Cross-Sectional Study from NHANES, a Nationally Representative Survey
Authors: He Yi , Lan Ying
Published: July 2024

Background: Iron status abnormalities are prevalent among postmenopausal women and have been implicated in cardiovascular disease (CVD) risk.
Objective:To explore the association between iron status and CVD risk in postmenopausal women.
Methods: We conducted a nationally representative cross-sectional study in the United States using data from five NHANES survey cycles (1999-2006, 2017-2018). Our analysis included 3,681 participants, among whom 11.41% (420/3681) had prevalent CVD. Iron status was assessed using hemoglobin (Hb), serum ferritin (SF), and transferrin saturation (TSAT). Multivariable logistic regression examined the correlation between SF levels and CVD risk. Given the nonlinear nature of the relationship, weighted quantile sum (WQS) regression and Bayesian kernel machine regression (BKMR) models were employed for further analysis.
Results: Multivariable logistic regression revealed a significant negative correlation between SF levels and CVD risk, with a nonlinear pattern and an inflection point at 123 ng/mL for SF. Both WQS and BKMR models indicated a negative association between iron status biomarkers and CVD risk, with Hb showing the most significant influence. Mediation analysis identified serum creatinine as a mediator in the association between iron status biomarkers and CVD risk.
Conclusions: This study reveals an association between iron status biomarkers and CVD risk in postmenopausal women, with serum creatinine partially mediating this relationship. These findings contribute to understanding the mechanisms linking iron status and cardiovascular health in postmenopausal women and suggest potential targeted intervention strategies. However, longitudinal studies are needed to validate these findings and explore early intervention strategies for preventing CVD.
Modelling personal temperature exposure using household and outdoor temperature and questionnaire data: implications for epidemiological studies
Authors: Xia Xi , Chan Ka Hung , Niu Yue , Liu Cong , Guo Yitong , Ho Kin-Fai , Yim Steve Hung-Lam , Wang Baihan , Doherty Aiden , Avery Daniel , Pei Pei , Yu Canqing , Sun Dianjianyi , Lv Jun , Chen Junshi , Li Liming , Wen Peng , Wu Shaowei , Lam* Kin Bong Hubert , Kan* Haidong , Chen* Zhengming
Published: July 2024

The reliance of outdoor exposure data in epidemiological studies on temperature entails important uncertainties from personal exposure misclassification. We analysed ~88,000 concurrent person-hours of measured personal, household (kitchen and living room), and outdoor temperatures collected in the summer (MAY-SEP 2017) and winter (NOV 2017-JAN 2018) in rural and urban China. The temperatures across microenvironments were strongly correlated (Spearman’s ρ: 0.86-0.92) in summer. In winter, personal temperature was strongly related to household temperatures (ρ: 0.74-0.79) but poorly related to outdoor temperature (ρ: 0.30). Random forest (RF) algorithm identified household and outdoor temperatures and study date as top predictors of personal temperature exposure for both seasons, and heating-related factors were important in winter. Multivariable linear regression and RF models incorporating questionnaire and device data performed satisfactorily in predicting personal exposure in both seasons (R2summer: 0.92; R2winter: 0.68-0.70). Using generalised additive mixed effect models, we found consistent U-shaped associations between measured and predicted personal temperature exposures and heart rate (lowest at ~14.5ºC), but a weak positive linear association with outdoor temperature. Personal and outdoor temperatures differ substantially in winter, but prediction models incorporating household and outdoor temperatures and questionnaire data performed satisfactorily. Exposure misclassification from using outdoor temperature may produce inappropriate epidemiological findings.

*Kin Bong Hubert Lam, Haidong Kan, and Zhengming Chen are joint senior authors.