Triagem neonatal para anemia falciforme, em um hospital geral de Taubaté, SP
Authors: Santos Sandja Assis Fernandes dos , Reis Lívia Aparecida Maia Braga de Campos , Toledo Maria Cecília Barbosa de , César Ana Cristina Gobbo 
Published: May 2018

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</style> <![endif]--> <p class="MsoNormal" style="text-align: justify;"><span style="font-size: 11pt;">A doença falciforme se dá por alteração genética que resulta na produção da hemoglobina S. A triagem neonatal é fundamental para o diagnóstico dessa doença. Foi realizado um estudo observacional em 8911 recém-nascidos em um hospital geral de Taubaté, que fizeram o teste do pezinho, entre 2005 e 2008. Foram analisados os resultados de exames do banco de dados do Ambulatório de Pediatria e os prontuários dos recém-nascidos e suas mães, o<span>rganizados por ano, sexo e etnias dos envolvidos. O diagnóstico do teste considerou</span>: perfil hemoglobínico normal (HbFA), anemia falciforme (HbFS), traço falciforme (HbFAS), traço da hemoglobina C (HbFAC) e da hemoglobina D (HbFAD). Dos avaliados<span>, 51,34% eram do sexo masculino, 48,27% do feminino e 0,39% de sexo não-determinado. Apenas um menino apresentou anemia falciforme (0,01%), e 168 recém-nascidos (1,88%) foram diagnosticados com traço falciforme.</span></span><span style="font-size: 11pt; color: black;"> </span><span style="font-size: 11pt;">Para as demais variantes hemoglobínicas, a representatividade foi pouco significante. <span style="color: black;">Correlacionando o grupo étnico e os perfis hemoglobínicos, observou-se</span></span><span style="color: black;"> </span><span style="font-size: 11pt; color: black;">que a maioria das crianças com traço falciforme é branca e apresenta mães com a mesma cor de pele. Provavelmente, a maioria das mães negras e pardas relacionou-se com homens brancos, contribuindo para a baixa frequência de crianças com anemia falciforme.</span></p>