bluuebunny/crossref_metadata_2025 huggingface dataset:
Democracy and emancipation in teacher education: A summative content analysis of teacher educators’ democratic assignment expressed in policies for Teacher Education in Sweden and Ireland between 2000-2010
Authors: Edling Silvia , Mooney Simmie Geraldine
Published: December 2017

How questions concerning democracy and emancipation thread through teacher education is currently under theorized and there is a paucity of cross-national studies examining the problem. In this study, we draw from a number of theoretical frameworks for their discursive positioning of democracy and emancipation in teacher education and what we are calling teacher educators’ democratic assignment. The framework allowed us to identify key words which we then used for a limited content analysis of policy documents in two European countries, Sweden and the Republic of Ireland, in two separate timelines 2000/2002 and 2010/2012. Our findings indicate that despite significant cultural and contextual differences between the two education systems, key words linked to democracy and emancipation have significantly decreased in policy documentation in both countries in this timeline. This prompts our hypothesis that a paradigm shift has occurred in the discursive positioning of teacher educators’ democratic assignment. The findings suggest the need for a deeper discourse analysis of the four documents as the next phase in the research design. The findings while tentative have implications, well beyond two nation states, for contemporary issues in teacher education and society that require collective consciousness and action.
Longitudinal Network Stability of the Functional Impairment of Anxiety and Depression
Authors: Curtiss Joshua , Ito Masaya , Takebayashi Yoshitake , Hofmann Stefan G.
Published: December 2017

Anxiety and depression are comorbid conditions with significant functional impairment. This study examines the temporal changes in the network structure of the functional impairment associated with anxiety and depression. A clinical sample ( n = 1,667) of individuals from Japan completed a battery of self-report instruments to assess the degree and level of impairment of anxiety and depression. The network structure was estimated at two time points using partial correlation coefficients and the glasso regularization procedure. Several permutation tests were conducted to examine network changes over time. Global and individual features of the network were stable across time. Furthermore, depression was more central than anxiety at both time points. Results should be interpreted in light of cultural factors involving the Japanese sample. These results underscore the temporal stability of the functional impairment of anxiety and depression as well as the importance of depression in the overall comorbid network.
Why Do People Hurt Themselves? A New Conceptual Model of Nonsuicidal Self-Injury
Authors: Hooley Jill M. , Franklin Joseph C.
Published: December 2017

The motivation to avoid pain and injury is a fundamental instinct, crucial to the survival of individuals and species. Yet, each year, millions of people purposefully and directly injure themselves in the absence of suicidal intent. Nonsuicidal self-injury (NSSI) has perplexed psychologists for decades. To advance understanding of NSSI, we present a new model—the benefits and barriers model of NSSI. This model builds on the supported elements of prior models, integrates information from recent experimental and longitudinal NSSI studies, and closely aligns with advances in basic psychological science. The core tenets of this model are that (a) NSSI carries many powerful benefits that are accessible to most people, but (b) most people do not access these benefits because there are several natural or instinctive barriers that motivate them to avoid self-injury. Preliminary work based on this model has produced novel NSSI risk factors and an effective NSSI treatment approach.
Criteria Definitions and Network Relations: The Importance of Criterion Thresholds
Authors: Hoffman Michaela , Steinley Douglas , Trull Timothy J. , Sher Kenneth J.
Published: December 2017

Across various structured diagnostic instruments, the criteria used to diagnose alcohol use disorder (AUD) are not assessed consistently. For example, different instruments often pose questions that reflect different thresholds of the underlying symptoms. We consider the criteria for craving and the inability to cut down or stop drinking to demonstrate the influence of using different thresholds for a positive symptom endorsement with respect to the estimated edges of a symptom network. Results indicate that the utilization of these differing thresholds leads to significant differences in edge weights. Generally, higher thresholds relate more strongly to lower prevalence rate criteria and the reverse for lower thresholds. These findings have implications for reproducibility of effects in symptom networks and their generalization across studies.
The Impacts of Ethical Philosophy on Corporate Hypocrisy Perception and Communication Intentions Toward CSR
Authors: Shim Kyujin , Kim Jeong-Nam
Published: December 2017

This study investigates how perceptions of corporate hypocrisy from corporate social responsibility activities connect the public’s ethical philosophy to subsequent positive/negative opinion-sharing intention. With special attention to deontology and consequentialism in normative ethics of philosophy, the current study empirically tests a theoretical model of perceived corporate hypocrisy with two causal antecedents (i.e., individual moral philosophy of deontology and consequentialism), and the mediating role of corporate hypocrisy between such antecedents and the public’s subsequent communication intention (i.e., positive and negative opinion-sharing intentions) toward a firm. Results indicate significant mediation effects of corporate hypocrisy between personal ethical orientations and the public’s communication intention based on ethical attribution of crisis-related corporate social responsibility activities.
Is Love Color-blind? Racial Blind Spots and Latinas’ Romantic Relationships
Authors: Muro Jazmin A. , Martinez Lisa M.
Published: December 2017

The racial stratification literature is rife with examples of how color-blindness has become a dominant ideology among Whites to deny the continuing significance of race at work, school, and in everyday life. Less understood are the racial ideologies deployed by people of color. Drawing on 20 in-depth interviews, we examine how college-educated Latinas acknowledge or deny the significance of race and racial hierarchies in decisions about whom to date. We find Latinas who stated an openness to dating men of all racial/ethnic backgrounds both acknowledged racism and its impact on their own lives and also held clear racial preferences. Additionally, participants used negative racial tropes about Black and Asian men to exclude them as romantic partners while also self-racializing to explain White men’s seeming reluctance to date them. To explain our findings, we apply the concept racial blind spots to show how participants simultaneously dismissed and drew upon color-blind ideology to justify patterns of racial exclusion. As we argue, racial blind spots explain how members of minoritized groups internalize aspects of the dominant racial ideology, involuntarily upholding the very system that oppresses them.
Deserve’s Got Nothin’ to Do With It
Authors: Waddington David I
Published: December 2017

After the death of my daughter Zoe in neonatal intensive care unit (NICU), a colleague asked me whether my status as an academic philosopher changed my experience in the NICU. In this short narrative, I outline 5 ways in which philosophical perspective helped me understand and cope with our hospital experience.
Narratives of a Dying Woman: Contentious Meaning at the End of Life
Authors: Rambotti Simone
Published: December 2017

Advancement in medical science and technology enhanced the human capacity to intervene in the process of dying, forcing professionals and the public to face ethical dilemmas and question the boundary between life and death. The contentious discourse on this boundary is particularly salient given the unprecedented levels of population aging all over the world. This paper analyzes the discursive field surrounding a notable Italian end-of-life controversy. Combining field and narrative theories, the present study spans structural aspects and rhetorical mechanisms. Results show that not only are antithetical interpretations of the event tied to media’s ideological leanings, but the latter are also systematically associated with different sequential structures of headlines and story leads. Competing actors produce alternative frameworks by identifying different sets of perpetrators.
Reversible Macular Lesions in the Setting of Oral Pan-Fibroblast Growth Factor Inhibitor for the Treatment of Bladder Cancer
Authors: Prensky Colin , Marlow Elizabeth , Gupta Mrinali , Sales Christopher , Kiss Szilard , D’Amico Donald J.
Published: December 2017

The tyrosine kinase inhibitor, JNJ-42756493, is an oral pan-fibroblast growth factor receptor inhibitor being studied as an antineoplastic agent. It is currently the subject of a phase II clinical trial for the treatment of urothelial cancer. We report 2 patients who developed visual disturbance shortly after starting or increasing dosage of this medication and were found to have bilateral foveal detachments on ocular coherence tomography imaging. The first patient discontinued this medication and the retinal lesions resolved with a return to baseline vision within 4 to 6 weeks. After restarting the medication at a lower dose, neither visual disturbance nor retinal lesions recurred. In the second patient, lesions were found to greatly improve shortly after discontinuation of the medication but recurred even on a reduced dose regimen.
A Misdiagnosed Case of Orbital Tuberculosis With Intracranial Extension
Authors: Steen Kalila , Fialkov Jeffrey
Published: December 2017

We describe an interesting case of a 57-year-old man who presented with a rare case of orbital tuberculosis masquerading as sarcoidosis. The varied presentation of orbital tuberculosis may only become evident once a tissue diagnosis is available. Therefore, the dilemma in diagnosis of this rare condition highlights the need for definitive diagnosis through tissue biopsy by a plastic surgeon.
Granulomatous Mastitis of the Breast: A Malicious Mimic
Authors: Severs Frederick J. , Guevara Lindsey , Sam Kenny Q. , Roark Ashley , Benveniste Ana Paula , Ebuoma Lilian
Published: December 2017

Granulomatous mastitis (GM) is a rare and benign condition of the breast. The condition most commonly affects women of childbearing age and is commonly associated with pregnancy, breastfeeding, and oral contraceptive use. The symptoms and imaging characteristics of GM often mimic those of breast carcinomas. Imaging findings tend to be less pronounced by mammography, and GM can be mammographically occult, making sonography important in identifying the condition. Proper identification of this entity is important to prevent misdiagnosis and/or delayed treatment. The diagnosis is commonly made by tissue sampling under ultrasound guidance.
Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN
Authors: Elf Shannon , Abdelfattah Nouran S. , Baral April J. , Beeson Danielle , Rivera Jeanne F. , Ko Amy , Florescu Natalie , Birrane Gabriel , Chen Edwin , Mullally Ann
Published: December 2017

Key Points

The binding of mutant calreticulin to MPL can be uncoupled from MPL activation. The lectin activity but not the chaperone functionality of mutant CALR is required for cytokine-independent growth.
Seismic image undersampling — Resolution, visibility, and display
Authors: Neidell Norman S. , Charuk James
Published: December 2017

GeoQuest International Ltd. authors first developed quantitative seismic criteria for estimating seismic bed thinness — tuning plots and wedge models — more than 40 years ago. Today, more recently developed alternative methods of imaging such as seismic holography can recover much finer seismic resolution. Here, we offer a practical viewpoint to better understand thin and small in seismic terms for differing objectives and applications. We address resolution as in forming seismic images of the subsurface and not as a method for detecting special conditions or features using attributes or other indicators. Seismic holography draws upon the data redundancy inherent in the acquired data. It allows us (within the bounds of data information content, signal to noise, etc.) to choose spatial and time sampling to best address our objectives. Traditional limiting criteria, as developed by Nyquist, and the constraints of acquisition geometry must be applied differently. Sources, receivers, and time samples are appreciated as linked coordinates. We can sample at any spatial or time interval that the data will support and that is consistent with what we seek to accomplish. We could even decimate our data in field practice and lose no relevant information for many objectives. This can save both time and money. We show examples to more fully understand some of the many aspects of the interpretive significance of these findings.
Anesthetic Management During Atrial Septostomy in a Conjoined Thoraco-Omphalopagus Twin With Tricuspid Atresia and d-Transposition of the Great Arteries Before Separation: A Case Report
Authors: Richtsfeld Martina , Konia Mojca , Hiremath Gurumurthy , Kloesel Benjamin
Published: December 2017

Conjoined twins are uncommon with reported incidences of 1 in 30,000–200,000 births. They represent a heterogeneous population in regard to location of joint body parts and presence/extent of internal organ fusion. Positioning, airway management, possible presence of cross-circulation, and the fact that 2 patients require anesthesia for each procedure present significant challenges to the anesthesiologist. We report the anesthetic care of a conjoined twin set in which one of the patients presented with tricuspid atresia, d-transposition of the great arteries, and both atrial and ventricular septal defect. A balloon atrial septostomy was performed to allow survival after a separation procedure.
Scrambler Therapy for the Treatment of Chronic Central Pain: A Case Report
Authors: D’Amato Stephen J. , Mealy Maureen A. , Erdek Michael A. , Kozachik Sharon , Smith Thomas J.
Published: December 2017

Central pain syndromes affect several million people worldwide. A 52-year-old woman had central pain manifest as burning pain from her left foot to the knee for 12 years after treatment for a medullary cavernoma diagnosed after a right-sided brainstem bleeding episode. All this time, her baseline pain was 5–6/10 with spikes to 9–10/10 during activity. She underwent 10 daily Scrambler (Calmare) Therapy treatments (GEOMC, Inc, Seoul, Korea) with reduction in her pain from 9–10/10 to 0–0.5/10, then 5 more sessions a month later. Her baseline pain stayed at 2/10 at 140 days with spikes only to 5/10, and no additional medications. Scrambler (Calmare) Therapy deserves further study in central pain.
Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish
Authors: Bambino Kathryn , Zhang Chi , Austin Christine , Amarasiriwardena Chitra , Arora Manish , Chu Jaime , Sadler Kirsten C.
Published: December 2017

The rapid increase in fatty liver disease (FLD) incidence is attributed largely to genetic and lifestyle factors; however, environmental toxicants are a frequently overlooked factor that can modify the effects of more common causes of FLD. Chronic exposure to inorganic arsenic (iAs) is associated with liver disease in humans and animal models, but neither the mechanism of action nor the combinatorial interaction with other disease-causing factors has been fully investigated. Here, we examined the contribution of iAs to FLD using zebrafish and tested the interaction with ethanol to cause alcoholic liver disease (ALD). We report that zebrafish exposed to iAs throughout development developed specific phenotypes beginning at 4 days post-fertilization (dpf), including the development of FLD in over 50% of larvae by 5 dpf. Comparative transcriptomic analysis of livers from larvae exposed to either iAs or ethanol revealed the oxidative stress response and the unfolded protein response (UPR) caused by endoplasmic reticulum (ER) stress as common pathways in both these models of FLD, suggesting that they target similar cellular processes. This was confirmed by our finding that arsenic is synthetically lethal with both ethanol and a well-characterized ER-stress-inducing agent (tunicamycin), suggesting that these exposures work together through UPR activation to cause iAs toxicity. Most significantly, combined exposure to sub-toxic concentrations of iAs and ethanol potentiated the expression of UPR-associated genes, cooperated to induce FLD, reduced the expression of as3mt, which encodes an arsenic-metabolizing enzyme, and significantly increased the concentration of iAs in the liver. This demonstrates that iAs exposure is sufficient to cause FLD and that low doses of iAs can potentiate the effects of ethanol to cause liver disease.

This article has an associated First Person interview with the first author of the paper.
Immune function and the decision to deploy weapons during fights in the beadlet anemone Actinia equina
Authors: Lane Sarah M. , Briffa Mark
Published: December 2017

The ability to mitigate the costs of engaging in a fight will depend on an individual's physiological state. However, the experience of fighting itself may in turn affect an individual's state, especially if the fight results in injury. Previous studies found a correlation between immune state and fighting success, but the causal direction of this relationship remains unclear. Does immune state determine fighting success? Or does fighting itself influence subsequent immune state? Using the beadlet anemone Actinia equina, we disentangle the cause and effect of this relationship, measuring immune response once pre-fight and twice post-fight. Contrary to previous findings, pre-fight immune response did not predict fighting success, but rather predicted whether an individual used its weapons during the fight. Furthermore, weapon use and contest outcome significantly affected post-fight immune response. Individuals that used their weapons maintained a stable immune response following the fight, while those that fought non-injuriously did not. Furthermore, although winners suffered a similar reduction in immune response to losers immediately post-fight, winners began to recover pre-fight levels within 24 hours. Our findings indicate that immune state can influence strategic fighting decisions and moreover that fight outcome and the agonistic behaviours expressed can significantly affect subsequent immunity.
Altered stoichiometry of an evolved RNA aptamer
Authors: Ohuchi Shoji , Suess Beatrix
Published: December 2017

Inhibitory aptamers against a protein are promising as antagonistic reagents and repressive genetic components. Typically, improvement of such aptamers is achieved by acquiring higher binding affinity. Here, we report an alternative mechanism for the improvement of aptamer activity. Recently, we reported a transcriptional activator based on an inhibitory RNA aptamer against lambda cI repressor. We improved the aptamer through in vitro selection (SELEX) from a randomly mutagenized aptamer pool, followed by in vivo screening and truncation. Biochemical analyses indicated that the activity improvement was achieved by alteration of the complex formation stoichiometry, rather than by higher affinity or expression. Our results suggest an alternative strategy for improving aptamer activity.
Case Report: Treatment of systemic mastocytosis with sunitinib
Authors: Molderings Gerhard J. , Afrin Lawrence B. , Hertfelder Hans-Jörg , Brettner Stefan
Published: December 2017

Mast cell activation disease typically presents as chronic multisystem polymorbidity of generally inflammatory ± allergic theme.  Presently, treatment of the rare, cytoproliferative variant systemic mastocytosis employs empirically selected therapies to impede mast cell mediator production and action and, when necessary, inhibition of proliferation. Some tyrosine kinase inhibitors (TKIs) have been used successfully in uncommon cases of systemic mastocytosis not bearing that disease’s usual imatinib-resistant KITD816V mutation. Recently, sunitinib, a multi-targeted TKI, had been successful in a case of systemic mast cell activation syndrome. In addition, most allergy is principally a mast cell activation phenomenon, and sunitinib has been shown helpful in controlling a murine model of oral allergy syndrome. Here, we present the first use of sunitinib in systemic mastocytosis.
Technologies of Human Resources Management for Effective Intellectual Capital Management in the Organization
Authors: Соболь О. , Sobol O. , Лобачева А. , Lobacheva A.
Published: December 2017

The article considers existing approaches to the management of intellectual resources in foreign and Russian practices. Also the authors discuss about the structure of intellectual capital with includes human, structural and customer (customer) capital. The authors propose fi ve functions for the management of intellectual capital in modern organizations (creation, evaluation, development, storage, distribution and transfer of intellectual assets and knowledge). The research focuses on the challenges that is facing the personnel management services in the fi eld of intellectual capital management and, in particular, knowledge of the company. The authors propose to manage intellectual assets and knowledge in the company through the development of training and development systems of personal and talent management, internal communication and improvement of infrastructure of knowledge management system. To address these challenges, the article examines the current practice of creation of Corporate universities, as centers of development of personnel and knowledge management in a company. The authors analyze the functions of Corporate universities, their main task, and the types of trainers (internal and external). In addition, the article discusses modern technologies, contributing to the development, consolidation, and translation of knowledge and intellectual assets in an organization.
Preparation and Utilization of the Precursor Activated Carbon from Carbon Enriched Fuel Oil Fly Ash: Part II Removal and Speciation of Chromium(III and VI) from Wastewater
Authors: Abu-Rizaiza A. , Kadi M.W. , El-Shahawi M.S.
Published: December 2017

Activated carbon (AC) prepared from residual fly (FA) was activated by combined CO2-steam gasification and physically modified with procaine hydrochloride (PQ+Cl-). Modified AC was used as low cost and effective solid phase extractor (SPE) for removal, total determination and chemical speciation of chromium(III&VI) in wastewater. Pseudo-second order rate equation is proposed for assigning the kinetics of chromium(VI) sorption in aqueous HCl (1.0 mol L-1) by PQ+Cl-- modified AC . The data were correlated with surface structure of the SPE. A dual separation mechanism of chromium(VI) as a binary complex ion associate [PQ+.CrO3Cl-] in/on the modified AC via "weak base anion exchanger" and an added component of “surface adsorption” is proposed. At 2 mL min-1 flow rate Sorption of spiked chromium(VI) at known concentrations (0.5-20 mg mL-1) from water onto modified AC packed columns at 2 mL min-1 was achieved. The sorbed chromium(VI) species were successfully recovered (106.0±2- 110 ±3%, n=3) from AC packed column with NaOH (10 mL, 1.0 mol L-1). Chromium(III) after oxidation to chromium(VI) was also enriched and eluted from the AC packed column and analyzed. Modified PQ+Cl- AC packed column was also used for total determination and speciation of chromium(III & VI) species at trace levels in environmental water samples. Good apparent recovery percentage (94.6±6.3-102.0± 8.5 %) of chromium species was achieved confirming the analytical utility of the modified AC-packed column for removal, total determination and speciation of chromium(III & VI) species in environmental water samples.
Predicting Preferences for Pedestrian Bridges in Tehran, Iran
Authors: Nejad Nasim , Maulan Suhardi Bin , Kabudarahangi Mina
Published: December 2017

Pedestrian bridges as urban infrastructurs, could play a critical role toimprove aesthetic qualityof urban areas. In Tehran, most of the pedestrian bridges are built in a similar structure regardles to the visual characteristics of their environments. However, many studies haveconfirmed the importance of harmony between aesthetic qualityof the bridges and their context. This study attempts to identify the role of context in aesthetic perception ofpedestrian bridges and to identify the visual attributes that affect the preferences through a photo-questionnaire survey. Therespondentswere 384 students from Tehran's universities and they were asked to rate 34 scenes of similar structure pedestrian bridges in different urban settings. Data were analyzed by using factor analysis to reveal preferences dimensions and the factors that may affect the preferences dimensions. In addition, the participants were asked their opinions regarding attributes that they perceived important for pedestian bridges aesthetic. Subsequently, a multiple regression analysis was employed to examine relationship between preferences and aesthetic attributes.The triagulation of results from preference dimensions and multiple regression analysis reviled the importance of visual attributes in setings of the pedestrian bridges and underlined the role of context in the aesthetic preferences of pedestrian bridges. These factors should be considered during planning and design processes in order to improve aesthetic qualities of pedestrian bridges in urban landscape.
Comparison of the Quality of Chitin and Chitosan from Shrimp, Crab and Squilla Waste
Authors: Parthiban F. , Balasundari S. , Gopalakannan A. , Rathnakumar K. , Felix S.
Published: December 2017

Chitin and Chitosan obtained from the crustaceans are having more biological value such as physiological compatibility, non-toxicity, bio digestibility, adsorption and chelating capacity. These biological values of chitosan depend on the quality parameters which are directly related to the source of the raw material. In this study, three commercially available crustacean shell waste such as shrimp, crab and squilla were used for the extraction of chitin and chitosan. The chemical treatment of demineralization, deproteinization and deacetylation were used for the production of chitosan. The viscosity quality parameter of the shrimp chitosan (5300cPs) was better than the crab and squilla chitosan. It is due the high solubility (97.65%) of the shrimp chitosan in 1% acetic acid. The degree of deacetylation of the shrimp chitosan (81.24%) directly relates the solubility of the chitosan. The chitosan with these quality parameters considered to be the excellent biological value. The yield of shrimp chitosan (15.4%) was also more when compare to crab and squilla chitosan. These result showed that utilisation of shrimp shell waste for the production of chitin and chitosan will give more economical and biological value along with reduction of environmental pollution.
Changing roles in community health care: Delegation of insulin injections to health care support workers
Authors: Dutton Julie , McCaskill Kelly , Alton Sarah , Levesley Maria , Hemingway Cath , Farndon Lisa
Published: December 2017

Diabetes is a common long-term condition affecting many people many of whom require support with their insulin injections at home. These injections are often carried out by community nurses if individuals are unable to self-manage their condition. This paper describes a pilot project where health care support workers were trained to administer insulin at home for suitable patients. Four patients took part in the pilot study and two support workers were trained to give the insulin injections. The project was evaluated well by all those who took part. It freed up 80 hours of nursing time while also providing the support workers with an extended scope of practice and associated increased in job satisfaction. No untoward medication errors were reported as a result of this initiative. This project will now be rolled out to the wider nursing teams with a staggered approach to the delivery of the training to ensure there is not a detrimental effect on patient care.
Psychiatric nursing: An identity crisis?
Authors: king Malcolm
Published: December 2017

Malcolm King reflects on the history of psychiatric nursing and the impact of changing attitudes towards mental health on professional identities
Ensaio metodológico para a categorização territorial do município de Lisboa utilizando dados dos censos de 2011
Authors: Pereira Margarida Miguel , Nogueira Helena
Published: December 2017

A visão mais tradicional em Geografia perspetiva o território como uma realidade dicotómica onde se cruzam características sociodemográficas e biofísicas, afirmando a literatura a respeito, que ambas as dimensões territoriais coexistem e interagem. No entanto, o número de indicadores de cada dimensão é vasto e torna complexa a categorização do território - tarefa que gera conhecimento sobre as diferenças entre territórios e auxilia um melhor planeamento, mais direcionado e estratégico. O objetivo deste trabalho é categorizar a área do Município de Lisboa, ao nível da secção estatística, integrando informação sobre os aspetos físicos e sociais. Para tal utilizaram-se técnicas de análise estatística multivariada e complementares: Análise em Componentes Principais (aplicada aos aspetos físicos e sociais do território) e Classificação Hierárquica Ascendente (baseada nos fatores previamente extraídos na Análise em Componentes Principais). Os clusters resultantes foram mapeados e a sua autocorrelação espacial foi testada.
O passado em permanente construção. O património em transformação.
Authors: Capela de Campos Joana , Murtinho Vítor
Published: December 2017

Quatro anos após a inscrição da Universidade de Coimbra – Alta e Sofia na Lista do Património Mundial, será certamente um bom momento para se fazer uma reflexão sobre que transformações ocorreram, ou estão a ocorrer, no contexto urbano da cidade, quer no espaço físico do bem classificado e da sua área urbana de influência, quer nas suas dinâmicas socioculturais. Deste modo, este artigo incidirá, criticamente, sobre o processo transformativo da cidade de Coimbra, tendo em conta três eixos estratégicos para uma gestão integrada e de desenvolvimento sustentável no seu contexto urbano: a proteção e salvaguarda do património, a Paisagem Urbana Histórica e o desenvolvimento urbano, incidindo sobre a dinâmica de reabilitação do parque edificado e do espaço público. Verifica-se que a Universidade assumiu um ímpeto propositivo no primeiro eixo estratégico e que, o poder local, pela lógica da gestão espacial, assume esse ímpeto no terceiro eixo. Pela leitura transversal das transformações e dinâmicas urbanas ocorridas nos eixos equacionados, no contexto urbano, enquanto plataforma agregadora dos espaços físico e social dados por uma matriz cultural territorial, é possível trabalhar para um planeamento urbano, de forma integrada e ajustada às exigências que se vão colocando contemporaneamente, para alcançar uma maior qualidade de vida.
Simulation of lumbar and neck angle flexion while ingress of paratransit (angkot) in Indonesia as a preliminary design study
Authors: Sya’bana Yukhi Mustaqim Kusuma , Sanjaya Kadek Heri , Kurnia Muhammad Redho , Shippen James
Published: December 2017

This is the preliminary finding of a study to simulate lumbar and neck flexion while ingress to the paratransit. The result of simulation will determine design aspect criteria as a preliminary step before ideation and implementation design steps. Biomechanics of Bodies (BoB) is software that used to represent passenger task during paratransit ingress simulation, with skeleton model that used is height 165 cm and weight 65 kg. Environment to represent this simulation is measured Suzuki Carry SS 2013 as a private car that has been modified into a public transportation in accordance with the Indonesian government road-worthy test. Due to the low height of the entrance and the high ground clearance, lumbar and neck joint angle was a focus of this ingress simulation. The peak angle at the neck joint is 40° when 2 s skeleton nod in the door limitation ingress and lumbar flexion is 70° when 5 s skeleton is walking while bend over that will increase the load on that area. Based on biomechanical simulation approach, we may suggest the dimension of public transportation design framework developments, especially paratransit.
Frequency stability improvement of micro hydro power system using hybrid SMES and CES based on Cuckoo search algorithm
Authors: Djalal Muhammad Ruswandi , Setiadi Herlambang , Imran Andi
Published: December 2017

Micro hydro has been chosen because it has advantages both economically, technically and as well as in terms of environmental friendliness. Micro hydro is suitable to be used in areas that difficult to be reached by the grid. Problems that often occur in the micro hydro system are not the constant rotation of the generator that caused by a change in load demand of the consumer. Thus causing frequency fluctuations in the system that can lead to damage both in the plant and in terms of consumer electrical appliances. The appropriate control technology should be taken to support the optimum performance of micro hydro. Therefore, this study will discuss a strategy of load frequency control by using Energy Storage. Superconducting magnetic energy storage (SMES) and capacitor energy storage (CES) are devices that can store energy in the form of a fast magnetic field in the superconducting coil. For the optimum performance, it is necessary to get the optimum tuning of SMES and CES parameters. The artificial intelligence methods, Cuckoo Search Algorithm (CSA) are used to obtain the optimum parameters in the micro hydro system. The simulation results show that the application of the CSA that use to tune the parameters of hybrid SMES-CES-PID can reduce overshoot oscillation of frequency response in micro hydro power plant.
The structure of pathozoospermia in young men with post-pubertal visceral obesity and a non-aggravated andrologic anamnesis
Authors: Rozhivanov Roman V. , Kurbatov Dmitriy G.
Published: December 2017

Introduction. Given the frequent development of visceral obesity in men, it is important to study its effect on spermatogenesis.
Aim. Assessment of the structure of pathozoospermia in young men with post-pubertal visceral obesity and a non-aggravated andrologic anamnesis.
Materials and Methods. In a single, one-stage study, 80 men with post-pubertal alimentary visceral obesity aged up to 30 years were included. The length of the circumference of the waist, the level of gonadotropins and total testosterone, the antioxidant activity of the ejaculate, its electron microscopic examination were estimated. Statistically significant differences were considered between groups at p 0.05.
Results. 24% of men did not have pathosoospermia. The main pathogenetic phenomenon, revealed in patients with pathozoospermia, was astenozoospermia - 100%. There was also a high prevalence of teratozoospermia - 36%. The prevalence of oligozoospermia was 11% of cases. An increase in the content of spermatozoa with insufficiently condensed chromatin and a decrease in the antioxidant activity of the ejaculate were characteristic of all types of pathozoospermia in obese men. A decrease in testosterone levels was characteristic of oligozoospermia. At the same time, statistically significant negative correlations between waist circumference and testosterone level, quantitative indicators of ejaculate, its antioxidant activity, as well as a positive correlation between the waist circumference and the content of spermatozoa with insufficiently condensed chromatin were established.
Conclusions. In young men with post-pubertal visceral obesity and a non-aggravated andrologic anamnesis, the prevalence of pathozoospermia in our study was 76%. The most common was oligozoospermia, which was characterized by the presence of the syndrome of normogonadotropic hypogonadism, which developed in patients with the most pronounced visceral obesity. An increase in the content of spermatozoa with insufficiently condensed chromatin and a decrease in the antioxidant activity of the ejaculate is characteristic of all types of pathozoospermia in obese men, which is due to oxidative stress.
Niveles séricos de minerales en hembras de cría bovina en un establecimiento de la región de selva y pastizal pedemontano del norte de Salta.
Authors: MICHELOUD Juan F. , SUAREZ Victor H. , MARTINEZ Gabriela M. , ROSA Diana E. , VENTURA María Belén , MATTIOLI Guillermo A.
Published: December 2017

Las deficiencias minerales son un problema de gran impacto productivo a nivel mundial. En el Noroeste argentino (NOA) la cría extensiva es una de las actividades económicas  más importantes y está en franco crecimiento. En el NOA, los estudios sobre enfermedades carenciales son escasos y parciales. El presente trabajo tiene por objeto describir variaciones estacionales de los niveles séricos de calcio, fósforo, magnesio, cobre y zinc en vacas de cría y terneras de recría. En un establecimiento ganadero  se seleccionaron 20 vacas y 20 terneras que fueron mantenidos en condiciones de pastoreo y sin suplementación externa.  Se efectuaron muestreos de sangre a intervalos de 3 meses durante un año. Se determinaron niveles séricos de calcio, magnesio, cobre y zinc por espectrofotometría de absorción atómica y de fósforo por espectrofotometría uv-visible. Los resultados indican la existencia de hipocupremia moderada a leve en las terneras (48,6±11μg/dL) durante todos los períodos muestreados. Las vacas presentaron valores promedio normales (66±3,5 μg/dL) pero cercanos al límite inferior durante algunos muestreos. Se observaron niveles subnormales de fósforo durante el verano (diciembre y marzo) en ambas categorías. Este trabajo sugiere que el cobre y el fósforo pueden comportarse como factores limitantes en las condiciones evaluadas.
The study of Eimeria tenella infections in Poultry Birds in Ekiti State
Authors: Adewole Samson , Odeyemi Dolapo , Aleem Serifat , T.E Omoyeni
Published: December 2017

In developing countries, animal production is being subjected to great pressure to satisfy the demand for animal protein required by the continuous increasing human population and to have surplus for international trade. Coccidiosis is a major health problem of poultries. This aim of this study is to determine the prevalence of caecal coccidiosis infections in poultry birds in Ekiti State. Three poultry sites were randomly selected and studied in Ekiti state. 10,000 birds were examined out of which 1033 birds tested positive to coccidiosis infection. Test tube floatations for faecal content and wet smear preparation for the caecal lining were done to test the presence of Eimeria tenella(Et)based on the dimension of oocyst and respiratory disease respectively. The result showed the highest percentage of Et infection in Yomi poultry farms in Ifaki Ekiti representing 6.8% while Daac poultry farms had the least percentage of 3%. The percentage occurrence of respiratory disease is highest in Daac farms with 6% and a least percentage of 3% in Christ's power poultry. The result implies that there is a still presence of Et infections in the poultries considered for study in Ekiti, thus the need for biosafety measures, information and protection programs against the disease.
Use Pattern and Seeking Behaviour of Students in National Institute of Technology, Jalandhar, India
Authors: Chohda Nirupma , Gupta Neeru
Published: December 2017

Determining use patterns and information seeking behaviour of users is consequential to enhance library collections, facilities, and services. This paper tends to investigate information seeking behaviour and use pattern of students on quality of procured information in National Institute of Technology, Jalandhar, India. Survey research method is adopted for the study. Analysis of data is done through percentage count. It is found that 70 per cent are aware about the e-journals and databases. The result indicated that both print and electronic e-journals are highly preferred by students but access them in other places then departmental library and 32.22 per cent respondents spent time more than hours for internet access. The study will be useful for the academic librarians in improving the shortcomings of their institutes and will procure the required e-journals for their Institutes. 
Use of ResearchGate by the Research Scholars of Pondicherry University: A Study
Authors: Singson Mangkhollen , Amees Mohammad
Published: December 2017

ResearchGate is an academic social network site designed primarily for scholars to create their own profiles, upload their scholarly work, and communicate among peers. The present study explores the motives, activities and benefit researcher seek or gain from joining ResearchGate academic social network. The result of the study indicates that ResearchGate is popular among research scholars in Pondicherry University. The motive of joining ResearchGate by scholar are many, however, majority of the scholars agrees that joining ResearchGate enable them to connect with people who have similar interests. Similarly, majority of the scholars stated that the main activity they involve themselves besides many activities in ResearchGate is reading articles and reviewing paper posted by others. Finally, ResearchGate has enhanced their ability to stay abreast with new/latest developments in their field of research. However, seeking employments using ResearchGate is the least research scholars anticipate. 
Ethyl 4-(4′-heptanoyloxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylate Prevents Progression of Monocrotaline-induced Pulmonary Arterial Hypertension in Rats
Authors: Malik S. M. , Deep Satyanarayan , Ranjan Rahul , Prasad A. K. , Prasad Dipti N , Singh Shashi Bala , Kohli Ekta
Published: December 2017

Therapies to prevent onset and progression of pulmonary arterial pressure are not very effective yet. This study was designed to investigate the effects of a novel dihydropyrimidinone, ethyl 4-(4′-heptanoyloxyphenyl)-6-methyl-3,4-dihydropyrimidin-2-one-5-carboxylate (H-DHPM) on pathogenesis of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH). For the same purpose, rats were injected intraperitoneally (i.p.) a single dose (60 mg/kg) of MCT which led to development of PAH in 21 days. MCT insult caused high mortality, pulmonary vascular and parenchymal remodelling. Since the course of PAH pathogenesis is characterised by an early onset and progression phases, H-DHPM was administered i.p. at 30 mg/kg dosage in MCT pre-injected animals either from day 0 through day 21 or day 14 though day 21 of MCT injection in two separate treatment groups. H-DHPM significantly improved survival, prevented remodelling of pulmonary vasculature and parenchyma and subsequently ameliorated PAH pathogenesis. Moreover, we observed significant decrease in right ventricle hypertrophy, measured by wet weight of right ventricle (RV) divided by wet weight of left ventricle plus septum (LV+S), in H-DHPM treated groups as compared to MCT injected animals. These findings suggest H-DHPM not only prevented development of PAH but also treated the PAH pathogenesis in progressive phase. In conclusion, our data determines H-DHPM, might be a future drug for the prevention of PAH.
Evaluation of Antioxidant Activity, Radical Scavenging, and Reducing Power of Clove Oil and Clove Oleoresin in Comparison with Natural and Synthetic Antioxidants in Chevon (Capra aegagrus hircus) and Chicken Meat
Authors: Sultana Khudsia , Jayathilakan K. , Pandey M. C.
Published: December 2017

The antioxidant effects of clove oil (CO) and oleoresin (OR) in two species of meat i.e. chicken and chevon during refrigerated storage (4±1°C) were investigated. The antioxidant potential (AOP) and radical scavenging activities were compared with natural (α-Tocopherol & L-ascorbic acid) and synthetic antioxidants (BHA & TBHQ). CO & TBHQ, BHA & OR and L-ascorbic acid and α-Tocopherol produced 84-79%, 68-77% and 68-59% AOP respectively in both species. DPPH and ABTS methods of scavenging assay established better scavenging capability of CO and TBHQ in comparison with other treatments. Significant reduction (p<0.05) in FRAP values was observed in CO & TBHQ in both species of meat. The order of antioxidant potential, scavenging activity and reducing power was in the order of CO>TBHQ>OR>BHA>Tocopherol>L-ascorbic acid. All the antioxidant assays analysed demonstrated a very significant correlation (p<0.05) between each other. The results suggest that CO and OR through their antioxidant effects are potentially useful in preserving meat products.
A Design of Experiments Methodology for Evaluating Configuration for a Generation Next Main Battle Tank
Authors: Rahman Abdur Rahman Hafeezur , Malik Shaik Ameer , Kumar Jagath Rajesh , Balaguru Vadivelu , Sivakumar Palanivel
Published: December 2017

Combat vehicles for generation next main battle tank requires state-of-the-art technologies to counter advanced threats both from conventional and un-conventional sources across various theatres of operation. In addition, they require strategic mobility by road, rail, air and sea. Under such conditions, the trend across the world has been to converge on configurations that are lethal, agile, modular systems and interchangeable mission based turret configurations along with higher survivability which imposes limitations on mobility as mass increases. To achieve all the user objectives as laid down in the qualitative requirements, it is prudent to focus the attention on weight management. The traditional approach of weight management is time consuming, for which an alternate approach using design of experiments is proposed in this paper. To carry out this study, two configurations are selected namely evolutionary and revolutionary design. Keeping the outer boundary as the constraint, a simple linear regression and analysis of variance are carried out with mass and volume data from various systems and sub-systems. Subsequently, the accuracy of the analysis is ascertained using a test of hypothesis using PHStat software. Although this study discusses configuration, the factors responsible for reduced system mass and volume namely technology, materials, intelligence etc have not been discussed. Finally, from the outcome of the study it is observed that the revolutionary design configuration fares better compared to the evolutionary design configuration with a combat mass of only 41 t. 
Development and Characterization of Naproxen-Loaded Poly(vinyl alcohol) Nanofibers Crosslinked with Polycarboxylic Acids
Authors: Akduman Çiǧdem , Akçakoca Kumbasar E. Perrin , Özgüney Işιk
Published: December 2017

Poly(vinyl alcohol) (PVA) hydrogel nanofibers are a potential candidate for textile-based drug-release applications. Polycarboxylic acids 1,2,3,4-butanetetracarboxylic acid (BTCA) and citric acid (CA) are low-cost alternatives reported to easily crosslink electrospun PVA hydrogel. These can be directly added into the spinning solutions. One of the most efficient non-steroidal anti-inflammatory drugs (NSAIDs), Naproxen (NAP), was selected as a model drug for this study. The release mechanisms of drug-loaded electrospun PVA nanofibers are based on the diffusion of the drugs through the swollen PVA fibrous matrix and the release due to partial dissolution of the matrix. Control over drug-release characteristics can be provided through partial crosslinking of the PVA fibrous matrix.