bluuebunny/crossref_metadata_2025 huggingface dataset:
Validation of Oakland score for predicting adverse outcomes of acute lower gastrointestinal bleeding
Authors: Nguyen The Tan , Vo Phuoc Tuan , Ho Tan Phat , Ho Dang Quy Dung , Phan Trung Nam
Published: April 2023

Background: Gastrointestinal bleeding is a common emergency in medical facilities. In clinical practice, there are many scales used to evaluate the risk of poor prognosis (Rockall, Glasgow, Blatch Ford) and mainly applied in upper gastrointestinal tract. However, the prognosis of lower gastrointestinal tract diseases remains limited. The appropriate selection and the application of scales for assessing the risks of poor prognosis in acute lower gastrointestinal bleeding (ALGIB) cases are essential, assist the physician to direct the intensive management attitude as well as the waste of human resources and health economy. Oakland score has been considered as a simple, convenient score to assist clinicians quickly, accurately stratify the risk of ALGIB patients. This study aimed to validate the Oakland score for predicting adverse outcomes of ALGIB patients. Methods: A cross-sectional study was conducted at Cho Ray Hospital from Jan 2021 to May 2021, including patients aged ≥ 16 years who had indication of admission due to symptoms suggesting ALGIB and underwent lower gastrointestinal endoscopy. These patients were then followed-up to observe the adverse outcomes, including blood transfusion, endoscopic intervention, surgery and death. Area under the receiver operating characteristic curve (AUC) and the best cut-off value of Oakland score for predicting adverse outcomes of ALGIB patients were analyzed using SPSS software. Results: A total of 70 patients with mean age 59.5 ± 16.4, male/female ratio (1.5 : 1) was recruited in this study. 27/70 (38.6%) stopped bleeding spontaneously without any interventions. The rate of clinical outcomes was blood transfusion (33/43, 76.7%), endoscopic intervention (5/43, 11.6%), blood transfusion plus endoscopic intervention (2/43, 4.7%), blood transfusion plus surgery (2/43, 4.7%), blood transfusion plus DSA plus surgery (1/43, 2.3%), respectively. AUC for predicting blood transfusion and adverse outcomes of ALGIB patients were 0.95 (0.91 - 0.99) and 0.91 (0.84 - 0.98), respectively.
Oaklad score threshold of 21 showed that sensitivity and specificity for predicting blood transfusion were 94.7% and 78.1%, sensitivity and specificity for predicting adverse outcomes of ALGIB patients were 81.5% and 90.7% respectively. Conclusions: Oakland is an excellent score in order to predict clinical outcomes on ALGIB patients.
Key words: Oakland; acute lower gastrointestinal bleeding; colonoscopy
Evaluating the effectiveness and applicability of UBL (ubiquitousbased learning) in a nursing training course for dementia care
Authors: Ngo Thi Mong Tuyen , Nguyen Thi Anh Phuong
Published: April 2023

Background: The concept of Ubiquitous technologies has been introduced to medical education in several years, there has been limited publications, particularly in a nursing education. Purpose: This study assessed the effectiveness and the applicability of a UBL course in nursing training courses on dementia care. Materials and method: A controlled quasi-experimental study for 70 nursing students at Hue University of Medicine and Pharmacy were randomly selected and divided into control group with traditional teaching and research group taught by UBL. A pre-test and post-test assessed student’s knowledge (DKAT2 scale),
attitude (DAS scale) and confidence (CODE scale) on dementia care were done. Results: In the DKAT2 scale and DAS scale, the intervened average score in the research group is higher control group: DKAT2: N2 = 16.86, N1 = 15.48 (p < 0.005); DAS: N2 = 102.46, N1 = 98.37 (T-test N2-N1 = 1.233, p = 0.222). In the CODE scale, the difference is non statistically significant in the two research groups and control groups (Chi- Square = 0.108, p = 0.743). Assessing the applicability of UBL in nursing training courses on dementia care, 68.6% of students rated good (Chi-Square = 4.829, p = 0.028). Conclusion: UBL contributes to improving the knowledge, perceptions, and confidence effectively of nurses students in terms of caring for patients with mental impairments.
Key words: Ubiquitous-based Learning, Dementia, nursing training
Häckningsbiotop och boplatsval hos havsörn Haliaeetus albicilla på Gotland
Authors: Wiss Lars-Erik
Published: April 2023

Nest site features and habitats of the White-tailed Eagle Haliaeetus albicilla were studied in Gotland, Sweden, during 2008–2017. Here, the entire population depended on suitable trees for nesting. The mean age of the nesting trees was 173 years. Only 9% of these trees were younger than 125 years. The mean distance from nests to roads was 400 metres. The mean distance to permanent residences and recreational cottages was 1.5 km and 1.2 km, respectively. Although the nests were not located far from human activities, the eagles were very shy. Therefore, they need protected areas around the nesting trees, especially during the breeding season.
“Propuesta de la creación de una pyme de productores de caña de azúcar en el municipio de Carlos A. Carrillo"
Authors: Sánchez Patricia Margarita Villar , Troncoso Dora Silvia Barradas , Mora María Elena Téllez
Published: April 2023

La globalización ha generado oportunidades para todos los países competitivos en el ámbito mundial, permitiéndoles alcanzar nichos de mercado en diferentes partes del mundo. Sin embargo, la globalización también margina a todos aquellos sectores comerciales de un país que no se encuentran funcionando eficazmente dentro de un mercado.  Las exportaciones son una gran solución para cualquier país que quiera hacer crecer su economía, exportar es enviar un bien o servicio a otra parte del mundo, con el propósito de comercializar, además de que se establecen bajo circunstancias determinadas. Las comercializaciones son de gran ayuda para el país, debido a que existen ingresos de capital y además, lo hace más competitivo. Se pretende que el futuro exportador comercialice productos de calidad, para colocar al país exportador como uno de los principales países en los intercambios.  Actualmente, en México, las personas o empresas que desean exportar enfrentan la falta de capacitación en materia de comercialización internacional, el poco conocimiento de algunos de los productores, los problemas de financiación y las barreras arancelarias. Se presenta una propuesta de creación de PYME de productores de Caña de Azúcar en el Municipio de Carlos A. Carrillo.
Tumor venéreo transmissível cutâneo em canino – relato de caso
Authors: Gollmann Bruna Giovana de Oliveira , De Oliveira Louisa Clara Custodio , Moreira Eberson Batista dos Santos , Chiminelli Junior Danilo Aires , Kolling Giovani Jacob
Published: April 2023

O Tumor Venéreo Transmissível (TVT) é uma neoplasia contagiosa de origem natural que atinge principalmente a mucosa genital, podendo ocorrer de forma cutânea, sendo esta pouco descrita na literatura. Este trabalho objetiva relatar um caso de TVT cutâneo em um canino sem raça definida. O animal apresentava diversos tumores cutâneos em todo o corpo, principalmente na região dorsal, sendo alguns ulcerados e não havendo comprometimento de mucosa genital. Para tratamento utilizou-se a quimioterapia com sulfato de vincristina onde, após a terceira sessão do tratamento, observou-se melhora considerável com a redução de ulcerações, redução de diâmetros nodulares e supressão da secreção serossanguinolenta, podendo ser vista a formação de tecido de granulação evidenciando o início do processo de cicatrização. Após seis sessões de tratamento quimioterápico foi possível constatar a remissão total dos tumores. Conclui-se que o diagnóstico correto e a utilização do tratamento descrito resultaram na cura do paciente.
A importância do PAM (Plano de Auxílio Mútuo) em apoio ao trabalho do Corpo de Bombeiros no Distrito Industrial de Ponta Grossa
Authors: De Oliveira Carlos Alberto
Published: April 2023

O presente artigo vislumbra a atuação do PAM (Plano de Auxílio Mútuo) na relação com as empresas do Distrito Industrial do município de Ponta Grossa, tendo como ideia central demonstrar como a atuação do Plano de Auxílio Mútuo contribui para a prevenção e segurança das empresas daquela localidade, contribuindo assim nos serviços prestados pelo Corpo de Bombeiros. Foi utilizado o método indutivo, onde observou-se individualmente os fenômenos, identificando as coincidências entre eles e a consequente generalização, partindo da análise dos casos concretos para se chegar a uma conclusão. O PAM é uma organização sem fins lucrativos, que tem como objetivo incentivar a criação de meios de colaboração mútua no caso de emergências entre as empresas privadas, públicas e órgãos públicos municipais, estaduais e federais, para compor uma força tarefa capaz de atuar de forma rápida e adequada no atendimento a emergências que porventura venham acontecer. Buscou-se responder à questão da pesquisa: “O Plano de Auxílio Mútuo ajuda a promover a prevenção e consequentemente a segurança das empresas do Distrito Industrial de Ponta Grossa”? Para tanto, mostramos a importância do PAM para o Corpo de Bombeiros de Ponta Grossa, tendo como preocupação identificar as dificuldades apresentadas e os desafios enfrentados atualmente pelo PAM no município. Por fim, procuramos mostrar aspectos positivos que resultam no desenvolvimento local para as empresas do Distrito Industrial e para o Corpo de Bombeiros de Ponta Grossa, assim como identificamos pontos a serem ajustados, os quais irão produzir melhorias nas atividades do PAM, e, consequentemente na segurança das empresas e do trabalho da corporação.
Automedicação por acadêmicos do curso de farmácia de uma instituição de ensino superior privada no interior da Bahia
Authors: Araújo Clerislane Silva , Rocha João Marcos Rodrigues , De Souza Enzo Costa
Published: April 2023

Introdução: Automedicação é entendida como a utilização de fármacos por iniciativa própria, sem prescrição, orientação e acompanhamento do profissional de saúde habilitado no que se refere a medicamentos e o seu uso clínico. Os anti-inflamatórios esteroides e não esteroides, podem ocasionar sérios riscos a saúde, com efeitos colaterais indesejáveis, intoxicação medicamentosa, mascaramento de doenças de alta e baixa gravidade, e óbito. O uso de medicamentos sem prescrição médica ou orientação do profissional farmacêutico, é recorrente por estudantes universitários. Isso pode ser justificado por diversos morivos, com destaque socieconômico e patológicos. Objetivo: Investigar o perfil dos estudantes que fazem uso irracional de anti-inflamatórios em acadêmicos do curso de farmácia, no Interior da Bahia. Metodologia: Trata-se de um estudo transversal, quantitativo e exploratório, com pesquisa de campo, com 164 estudantes do curso de farmácia. Foi realizada a análise descritiva dos dados, seguidos pelo teste de associação Qui-quadrado de Pearson, através do software Jamovi. Resultados: Mostra predominância no gênero feminino, entre 18-30 anos, com diferença significativa entre a variante dependente (período letivo), com o gênero e o aconselhamento com o balconista e o farmacêutico. Assim, foi possivel observar que a prevalência do uso de medicamentos sem prescrição foi maior nos estudantes concluintes do curso de farmácia. Os AINEs mais utilizados foram o ibuprofeno, dipirona e a nimesulida. Os AIEs, com predominância da prednisona, budesonida e o dexametasona.
A cirurgia ortognática, em indivíduos com discrepância esquelética classe II, melhora o quadro de Síndrome da Apneia Obstrutiva do Sono?: uma revisão sistemática
Authors: Ribeiro João Vitor de Camargos , Barcellos Bhárbara Marinho , Da Silveira Isabela Toledo Teixeira , Mariotto Lígia Gabrielle Sanches , Carvalho Luciano Reis de Araújo , Duarte Bruno Gomes , Mello Marina de Almeida Barbosa , Yaedú Renato Yassutaka Faria
Published: April 2023

O objetivo deste estudo foi avaliar se a Síndrome da Apneia Obstrutiva do Sono de indivíduos com discrepância esquelética de Classe II, apresenta melhora após a cirurgia ortognática de avanço bimaxilar. Esta revisão sistemática foi realizada através da busca eletrônica nas bases de dados MEDLINE (PubMed) e Scopus (Elsevier). Estudos que avaliaram variáveis pré e pós-operatórias relacionadas a SAOS e via aérea foram incluídos. Os dados coletados e analisados foram: características demográficas; polissonografia pré e pós-operatórias; índice de massa corporal; análise subjetiva de sonolência; cirurgia realizada; tempo de acompanhamento pós-operatório; análise da via aérea; reintervenção; cirurgias prévias envolvendo via aérea. A qualidade dos estudos foi avaliada utilizando a Escala de Hawker. A busca inicial englobou 155 artigos e ao final 5 foram incluídos. No total 54 pacientes foram submetidos a cirurgia ortognática, sendo a maioria (90,7%) homens com idade média de 43,7 anos. A média do IMC foi de 34,05 kg/m2. O tempo de acompanhamento pós-operatório variou de 2 a 6 meses. Em nenhum dos pacientes da amostra foi necessária a reintervenção. De acordo com os parâmetros observados nos exames de polissonografia apresentados nos estudos selecionados nesta revisão sistemática, pode-se concluir que o avanço mandibular combinado ou não com a cirurgia maxilar ou de mento, contribui para uma melhora do valor de IAH e por conseguinte, com a análise subjetiva do sono e com o quadro de SAOS.
Óleos essenciais no controle in vitro de bactérias patogênicas e deterioradoras de alimentos
Authors: Machado Terezinha Feitosa , Pereira Rita de Cássia Alves , Magalhães Hilton César Rodrigues
Published: April 2023

O objetivo deste trabalho foi avaliar a atividade antimicrobiana, in vitro, dos óleos essenciais de Cymbopogon citratus e Lippia alba (Mill) N. E. Brown contra microrganismos patogênicos e deterioradores de alimentos. Os óleos foram extraídos por hidrodestilação e caracterizados quanto à composição química por cromatografia gasosa. A atividade antimicrobiana dos óleos foi determinada pelo método de difusão em ágar e, as concentrações inibitórias e bactericidas mínimas foram determinadas pelo método de microdiluição em caldo. As espécies bacterianas utilizadas foram Staphylococcus aureus, Listeria monocytogenes, Listeria innocua, Escherichia coli, Pseudomonas aeruginosa e Salmonella choleraesuis. Os principais componentes identificados no óleo de C. citratus foram geranial e neral, enquanto os componentes majoritários do óleo de L. alba foram e-citral e neral. Os dois óleos apresentaram atividade antimicrobiana contra todas as espécies bacterianas testadas. A zona de inibição do óleo de C. citratus variou de 33 ± 2,8 mm (S. aureus) a 10 ± 0,0 mm (S. choleraesuis) e a zona de inibição do óleo de L. alba variou de 15,5 ± 0,7 mm (S. aureus) a 8,0 ± 0,0 mm (P. aeruginosa). As concentrações inibitórias mínimas (CIM) e as concentrações bactericidas mínimas (CBM) do óleo essencial de L. alba foram menores para S. aureus, L. monocytogenes, L. innocua e E. coli, enquanto que o óleo de C. citratus apresentou CIM e CBM menores para P. aeruginosa e S. choleraesuis. Os resultados mostram que os óleos essenciais avaliados podem ser uma alternativa eficiente para o controle de bactérias patogênicas e deterioradoras de alimentos.
AKULAH JALAN, KEBENARAN DAN HIDUP
Authors: Purba Mida
Published: April 2023

Focus of this article is elaborating the meaning of the words of Jesus which we find in the gospel of John 14: 6 “I am the Way, the Truth and the Life”. The purpose is showing that a proper understanding regarding the meaning of the words of Jesus provides a way to know who Jesus is and to take a proper attitude towards it. Knowing him and accepting him continuously is the way to be mature in faith. In order to do that first, I elaborate a simple notion about what is prayer and what is not prayer, a relation with God. Second, I show that a human being essentially free to give and receive form of his or her life. Third, I point out the meaning of John 14: 6 “I am the Way, the Truth and the Life”. I end this article with a conclusion. The method that I used in doing this article is mystagogy.
Survival Analysis of COVID-19 Patients in an Iranian Population
Authors: Rafati Shideh , Aghamolaei Teamur , Bahrampour Abbas , Khorrami Farid , Kheirandish Masoumeh , Khosravi Bahareh , Rafati Foozieh
Published: April 2023

Background: Coronavirus disease 2019 (COVID-19) has a high rate of mortality, but data regarding its prognosis are scarce. This study aimed to identify the risk factors associated with mortality and survival of COVID-19 patients in a southern province of Iran. Materials and Methods: This was a cross-sectional study with a secondary database of 3172 people who were admitted to hospitals for COVID-19 treatment. Relative risk (RR) was computed to estimate mortality risk between groups, and the log-rank test was used to compare the survival functions in different levels of categorical variables. Finally, the multivariable extended Cox model was employed to determine the factors that affected the survival of COVID-19 patients. Results: The 10- and 15-day survival rate of 3172 patients was 89% and 80%, respectively, and the median survival time was 30 days. Based on the extended Cox model, age, oxygen therapy, intensive care unit (ICU) admission, invasive ventilation, chronic cardiac disease, chronic kidney disease, and cancer were the most important variables affecting the survival of COVID-19 patients. Conclusion: Older people (older than 40 years) and those with comorbidities (e.g., chronic cardiac disease, chronic kidney disease, and cancer) had a higher mortality rate; therefore, health-related organizations need to plan for the prevention and early detection of comorbidities to reduce the burden of diseases such as the pandemic of COVID-19 as much as possible in the future.
Inflammation and JAK/STAT Signaling: New Clues for the Treatment of COVID-19
Authors: Shirazinia Reza , Afshari Mahdi , Golabchifar Ali Akbar , Arab Hosein Ali , Panahi Mishkar Abolfazl
Published: April 2023

The coronavirus disease 19 (COVID-19) outbreak in Wuhan, Hubei province, is a global health problem affecting about 212 countries around the world, highlighting the importance of the global recruitment of scientists to find a way for managing this burden. So far, many studies have been conducted to find a treatment for COVID-19, some of which indicated promising results. In this situation, gathering the previously published evidence may provide new hypotheses/ solutions in this regard. Based on the role of inflammation in COVID-19-related deaths, we attempted to find a rational relationship between Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling and COVID-19 and inform JAK/STAT signaling inhibitors as candidates to manage or even prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Therefore, it is hoped that the present study provides new clues about the relationship between JAK/STAT signaling and the SARS-CoV-2 infection to highlight the role of JAK/STAT inhibitors as a possible treatment for managing inflammatory situations observed in the SARS-CoV-2 infection.
Combination Effect of Ginger and Rosemary Extracts on CT-26 Mouse Colorectal Cancer Cells
Authors: Makaremi Shima , Mosayebi Ghasem , Ghazavi Ali , Ganji Ali
Published: April 2023

Introduction: This study aimed to evaluate the potential apoptotic effects of Zingiber officinale Roscoe (ginger) and Rosmarinus Officinalis L. (rosemary) combination extracts on the mouse colorectal cancer cell line. Methods: After the preparation of the extracts, cytotoxicity and cell viability were measured by MTT assay, and the IC50 of each extract was calculated. Next, the combination index (CI) of the mixture of the extracts was evaluated by CompuSyn software. The apoptosis induction was evaluated by Annexin V/PI assay and caspase-3, Bcl-2, and Bax genes expression. Results: The viability of the CT-26 cells exposed to ginger and rosemary extracts was significantly reduced in a dose-dependent manner (P<0.05) with the confirmed synergistic effect of the mixture (CI=0.89). Moreover, treatment of the cells with IC50 concentration of the extracts induced apoptosis, especially in the mixture group (P<0.001). Additionally, expression levels of Bax and caspase-3 genes increased in the mixture group compared to the control (P<0.001). Expression levels of Bcl-2 were increased in the rosemary and mixture groups compared to the control group (P<0.05). Conclusion: The results of the present study revealed that the mixture of the extracts has synergistic cytotoxic and apoptotic effects on colorectal cancer cells. Therefore, the mixture of ginger and rosemary extracts can be used as a potential complementary therapy in the context of other therapeutic approaches for colorectal cancer.
A Survey on the Sanitary Condition and Prevalence of Listeria monocytogenes in Commercial Refrigerators in Khuzestan Province, Iran
Authors: Maktabi Siavash , Zarei Mehdi , Salehi Hadi
Published: April 2023

Background: Listeria monocytogenes can grow in a variety of foods that are stored in refrigerators. This bacterium can adhere to various surfaces and form biofilms. Given that refrigerator temperature can support bacterial growth and proliferation, increasing the number of bacteria in refrigerator spaces endangers the consumer’s health. Objective: The purpose of this study was to investigate the prevalence of L. monocytogenes and the sanitary conditions of commercial refrigerators used in food supply centers in Khuzestan province, southwest Iran. Materials and Methods: Overall, 204 swap samples were collected from the inner surfaces of various industrial refrigerators in five different zones. The samples were enriched in Listeria enrichment broth and cultured on PALCAM agar plates. Suspected colonies were identified by biochemical tests and the polymerase chain reaction. Additionally, the sanitary condition of the refrigerator, method and duration of refrigerator cleaning, last washing date, and type of the applied detergent were recorded, and the antibacterial susceptibility of the isolates was tested as well. Results: The results demonstrated that four refrigerators (1.96%) located in Ahvaz (center) and Ramhormoz (east) were contaminated with L. monocytogenes. The internal temperatures of 67% of the refrigerators were above 5 °C, and most operators used a mixture of water and a dishwasher or water alone to clean their refrigerators. In addition, 31.9% of the refrigerators were in an unfavorable cleaning condition, and 32.8% of the refrigerators were not sealed properly. The isolates were resistant to streptomycin and represented intermediate resistance to tetracycline and penicillin. Conclusion: The contamination of industrial refrigerators with antibiotic-resistant L. monocytogenes may pose a threat to public health. Authorities should increase the monitoring of industrial refrigerators and provide the necessary training for refrigerator users.
Association of maternal diabetes during pregnancy with attention deficit hyperactivity disorder in offspring in an Iranian population: A case-control study
Authors: Mohammadzadeh Soleiman , Hamidi Samad , Rasouli Mohammad Aziz , Sahadatmand Bahar , Zareie Bushra
Published: April 2023

Background and aims: Gestational diabetes has long-term adverse consequences for both the mother and child and seems to be a risk factor for attention deficit hyperactivity disorder (ADHD) in children. However, no research has been conducted in this regard in Iran. Methods: This was a case-control study. The sample consisted of 225 children who were referred to the general and psychiatric clinic of Besat Hospital in Sanandaj and were evaluated for a history of maternal diabetes in the fetal period. The diagnosis of ADHD in children was based on a structured clinical interview with Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime version (K-SADS-PL) by a psychiatrist and a short and revised form of Conners’ parent scale. The data were analyzed using Stata 14. Results: The results showed that 25.3% of the mothers of children with ADHD had gestational diabetes during pregnancy, and 17.3% were taking diabetes medication. However, the results revealed that there is no statistically significant relationship between the history of gestational diabetes and ADHD (P=0.427). Furthermore, the logistic regression results demonstrated that the place of residence (P<0.027, OR=8.351) increases the probability of suffering from ADHD in children, while the age of the mother during pregnancy (P<0.031, OR=0.907) decreases the probability of the child suffering from ADHD. Conclusion: Although cohort studies have associated gestational diabetes with an increased risk of ADHD in children, the results of this case-control study do not support this association.
The effect of resistance training on blood pressure, apelin, ANP, PON1, adiponectin, H2O2, and ET-1 in hypertensive men
Authors: Baghaiee Behrouz , Dolatabadi Farahani Nasibeh , S Pescatello Linda , Davaran Hagh Elshan , Ebrahimi Khadijeh
Published: April 2023

Background and aims: Primary hypertension, an unexplained increase in blood pressure (BP), accounts for 90% of the cases of hypertension and remains a critical public health challenge. This study aimed to investigate the effects of 12-week resistance training (RT) on some vasodilators and vasoconstrictors in hypertensive men. Methods: This is a semi-experimental study. A total of 40 middle-aged men (45.3±3.2 years) with moderate hypertension (systolic BP [SBP] 140.5±0.3 and diastolic BP [DBP] 90.7±0.0 mm Hg) were randomly divided into the RT (n=20) and non-exercise control (n=20) groups. The 12-week dynamic RT program was performed at an intensity of 80% of one repetition maximum for 3 days per week (3 sets of 8 repetitions/3 days a week). Blood samples were taken from both groups at baseline and weeks 4, 8, and 12. Results: SBP and DBP decreased by -8.19±2.46 mm Hg (P=0.039) and -1.19±0.02 mm Hg (P=0.033) from baseline at week 12 in the RT group, respectively, compared to the control group (SBP; 8.22±2.49, P=0.04; DBP; -1.19±0.03, P=0.032). Adiponectin, apelin, atrial natriuretic peptide (ANP), and paraoxonase-1 (PON-1) serum levels increased from baseline at weeks 8 (P=0.01) and 12 (P=0.01), while endothelin-1 (ET-1) and H2 O2 decreased from baseline at weeks 8 (P=0.01) and 12 (P=0.01) in the RT in comparison to the control group. Conclusion: Overall, 12-week RT led to an increase in apelin, ANP, PON-1, and adiponectin. Increasing these markers reduces H2 O2 and ET-1, thus decreasing SBP and DBP in hypertensive men.
Head-to-Head Diagnostic Test Accuracy Meta-analysis of Colonoscopy and Fecal Immunochemical Test in Detecting Advanced Colon Neoplasia
Authors: Yaghoobi Mohammad , Mehraban Far Parsa , Mbuagbaw Lawrence , Yuan Yuhong , Armstrong David , Thabane Lehana , Moayyedi Paul
Published: April 2023

Background: Studies on the use of fecal immunochemical test (FIT) in colorectal screening have long assumed perfect accuracy for colonoscopy. No study to date has directly compared the diagnostic accuracy of colonoscopy and FIT to detect advanced neoplasia (AN) in a head-to-head diagnostic accuracy meta-analysis. Methods: A comprehensive electronic search was performed for a head-to-head comparison of FIT and colonoscopy using a third acceptable reference standard in asymptomatic adults. Cochrane methodology was used to perform a head-to-head diagnostic test accuracy (DTA) meta-analysis. Quality assessment tool for diagnostic accuracy studies-2 (QUADAS-2) was used to assess the risk of bias in included studies. Results: Two studies met the eligibility criteria. Overall sensitivity and specificity were 98.5 (95% CI 96.3-100%) and 100% (99.9-100%) for colonoscopy and 16.4% (10.3-22.6%) and 95.4% (94.3-96.4%) for FIT. Colonoscopy was significantly better than FIT (P < 0.0001). The positive and negative likelihood ratios (LRs) were 1.75 (1.57-1.96) and 0.03 (0.01-0.08) for colonoscopy and 3.02 (2.01-4.55) and 0.88 (0.82-0.95) for FIT, respectively. Conclusion: Colonoscopy provides significantly better diagnostic accuracy to detect AN compared with FIT (GRADE: ⨁⨁◯◯). Our study provided precise sensitivity and specificity of both colonoscopy and FIT and a revision in screening policies based on an updated cost-effectiveness analysis considering the results of the head-to-head analysis.
Intentional Ingestion of a Foreign Body – Why We Need Psychiatrists
Authors: Chauhan Ashish , Bodh Vishal , Sharma Rajesh , Sharma Brij
Published: April 2023

Foreign body ingestions are common medical emergencies. In adults, foreign body ingestions occur in patients with psychiatric disorders and prison inmates. A majority (80-90%) of foreign bodies pass spontaneously. Endoscopic and surgical interventions are required in only 10-20% and 1%, respectively. A plain radiograph may be the only diagnostic test required. A computed tomography scan may be needed when a perforation is suspected. Food boluses are the most commonly ingested foreign bodies. Snare and rat tooth forceps are frequently used accessories for the retrieval of foreign bodies. The focus of the emergency team is on the management of an acute case of foreign body ingestion, and the psychiatric aspect of the disease gets often ignored.
Faktor-Faktor yang mempengaruhi Nilai Perusahaan Non Keuangan yang terdapat di Bursa Efek Indonesia
Authors: Putri Deasy , Suryanto Suryanto
Published: April 2023

This study aims to examine the factors that affect the value of companies in non-financial companies in Indonesia. There are seven independent variables in this study, including: dividend policy, managerial ownership investment opportunity, leverage, profitability, firm size, earnings per share.Fifty eight companies listed during the period 2014-2016 in Indonesia were selected as samples using purposive sampling method. And data analysis is done by using multiple linear regression method.The results of this study indicate that there is a positive effect of dividend policy, profitability, company size, earnings per share on the value of the company. While investment opportunity, managerial ownership, and leverage have no effect on company value.
Analisis Teori Fraud Triangle dalam mendeteksi Financial Statement Fraud
Authors: Renata Felicia , Marlinah Aan
Published: April 2023

The purpose of this research is to examine the influence of financial stability, external pressure, personal financial need, financial targets, nature of industry, ineffective monitoring, quality of external auditor, auditor change, and audit opinion on financial statement fraud. The sample used in this research is the manufacturing companies listed in Indonesia Stock Exchange (IDX) for the period 2019 to 2021. The sample was selected using purposive sampling method and the results obtained were 75 companies or 225 data. The data of this research was tested using logistic regression analysis. The result of the analysis shows that financial stability, personal financial needs, nature of industry, and quality of external auditor have an influence on financial statement fraud, while external pressure, financial targets, ineffective monitoring, auditor change, and audit opinion have no influence on financial statement fraud.
STUDY OF TRAFFIC FLOW MANAGEMENT ON THE MAIN STREET IN PAVLOVSK
Authors: Artemov Alexander
Published: April 2023

Today, on the scale of small and medium-sized cities, there are certain problems associated with the introduction of Intelligent Transport Systems (ITS). Despite the existence of the same transport problems that characterize all cities in the Russian Federation today without exception, in cities with a low population size the introduction of new traffic management tools is not fully implemented, which is primarily due to the economic component of this type of activity. In such a case, a necessary measure is to develop alternative methods and approaches to eliminate existing traffic problems. In order to consider the traffic situation in one of the problematic areas of the city with a low population size, a study of the main street was carried out and measures to improve the management efficiency were proposed, taking into account the economic component.
ANALYSIS OF THE TRIBOTECHNICAL PROPERTIES OF MODIFIED VEGETABLE OILS AND PROSPECTS OF THEIR USE IN ROAD TRANSPORT
Authors: Medvedev Ilya , Savchenko Stanislav , Zhuzhukin Konstantin , Zhuzhukin Nikolai
Published: April 2023

Resource and energy saving is an important global problem. Vegetable oil based lubricants are becoming increasingly important in the industrial lubricants market due to their biodegradability, renewability, minimal environmental impact, excellent tribological performance and stringent environmental regulations. This review article discusses various aspects of biolubricants, such as the chemical composition of various vegetable oils, chemical modification methods used to synthesize biolubricants, the physicochemical and rheological properties of biolubricants, the tribological characteristics of biolubricants under various conditions, and various nanoparticles used to improve performance. biolubricants. In addition, the prospects for the use of bio-lubricants in road transport are considered.
Empowering Students’ Affective Factors in Teaching Speaking through Integrated Communicative Activities
Authors: Mujahidah  , Rauf Faridah Abdul , Dj Muhammad Zuhri
Published: April 2023

This study investigates the students' affective factors in learning to speak through integrated communicative activities. Communicative activities aim to develop students' ability to use language to interact with people in real situations. Practising communicative activities can certainly help students to develop their language abilities. Integrated communicative activities are assumed to be the best way to empower the students' affective factors. Communicative activities are needed to help students to boost the students' anxiety, motivation and self-confidence in learning to speak. The participants were students in the fourth semester of the English Education Department of State Islamic Institute Parepare. The quantitative research was conducted by using a random sampling technique. In-depth analysis showed three results, 1) the students believed they desired to speak in front of the class. They were not afraid and shy when their friend laughed or the teacher correction at them; 2) the students were enthusiastic and spirit about learning as a good opportunity in the future; 3) the students also had confidence that they have intelligence and communication ability. The study's results suggested that integrated communicative activities should be implemented in the class to empower the students' affective factors.
Pengendalian Kualitas Produk Batu Nisan di Kota Gresik dengan Pendekatan Seven Tools
Authors: Rosyidi Moh. Ririn , Narto Narto
Published: April 2023

In the Industrial Age 4.0, when business competition is increasing and growing, business people are also required to be able to maintain and increase their existence in products, This tombstone is one of the product needs when approaching the Idhul Fitri holiday because many people will replace the tombstones that have died or if a relative has passed away. Sadar Gresik UMKM produces tombstones and there is a defect problem that occurs, namely experiencing thin cracks and chipped corners of tombstones in April 2022 Sadar UMKM can produce an average of 41 gravestones in one day and for an average defect in 1 month 11 tombstones. In this study, aims to find out the quality control needed so that the tombstone products can control defects, by using the seven tools to find out the factors that cause defects and can control the defects by knowing the NP line on the control chart. Seven tools can also identify the causes and effects of defects and with the addition of 5W+1H recommendations will be made regarding the problems encountered. factors from the results of fishbone Diagrams that require evaluation which include human factors, materials, methods, environment where these factors cause the number of tombstone defects to be 174 thin cracks and tombstone corners to chip 121. To control defects in tombstone products so that at the midpoint of NP 11.8 is right at the midpoint of the control chart. From several factors that are already known in thin cracked tombstones, namely carrying out quality control of 5W + 1H tombstones, so that they can control these defects in accordance with predetermined product specifications/standards, the process of making tombstone products, employees who work on these have responsibilities, the need for training/skill training for the process of making the tombstones and monitoring the evaluation of the workers, the angle of the tombstones, namely carrying out quality control so as to minimize product defects, so that the quality produced is maintained according to the specified standards, the process of making tombstone products, employees those who do it have the responsibility, make repairs on a regular basis.
Pengaruh Stres Kerja Dan Persepsi Keadilan Organisasional Terhadap Turnover Intention Dengan Modal Psikologis Sebagai Pemoderasi
Authors: Primadineska Rasistia Wisandianing
Published: April 2023

This study aimed to examine the moderating role of psychological capital (psycap) on the relationship between job stress and perceived organizational justice (distributive, procedural and interactional) towards the turnover intention. This study used a survey method both online and in-person and used public accountants who already work for 1-3 years as participants. The results showed that psychological capital able to moderate the impact of work stress and perceived organizational justice towards turnover intention. Auditors who have a good psychological capital can suppress his desire to move even though he faced the work stress and the perception of organizational justice that may not comply with his wishes. The results of the study also support the theory of positive organizational behavior which states that psychological capital is the main variable that affects individual motivation and performance.
Peran Country of Origin dan Loyalitas Merek Terhadap Niat Beli Ulang
Authors: Aquinia Ajeng , Soliha Euis , Maskur Ali
Published: April 2023

Dalam penelitian ini bertujuan untuk menganalisa faktor-faktor yang bisa mempengaruhi niat beli ulang, diantaranya adalah country of origin dengan mediasi loyalitas merek. Dalam penelitian ini, meneliti pada pruduk Starbucks.Populasi dalam penelitian ini adalah konsumen Starbucks di Kota Semarang dengan menggunakan teknik purposive sampling yang memiliki kriteria sample pada konsumen yang telah mengkonsumsi produk Starbucks. Dalam penelitian ini, menggunakan instrumen berupa kuesioner. Uji validitas intrumen menggunakan analisis faktor, lalu untuk uji reliabilitas menggunakan Alpha Cronbach. Setelah itu data yang terkumpul dianalisis oleh metode analisis regresi berganda dan pengukuran mediasi dengan meggunakan Sobel Test. Hasil pengujian menunjukan bahwa country of origin berpengaruh positif terhadap loyalitas merek. Namun country of origin tidak berpengaruh terhadap niat beli ulang. Loyalitas merek berpengaruh positif terhadap niat beli ulang dan mampu memediasi sempurna antara country of origin dan niat beli ulang.
Persepsian Pada Motivasi Belajar: Penggunaan E-Learning Pada Mahasiswa Di Masa Pandemi
Authors: Rachmawati Lutfika , Adhipratama Agung Anugerah
Published: April 2023

Tujuan penelitian ini adalah mengetahui pengaruh persepsi konten, persepsi antarmuka, persepsi umpan balik, persepsi personalisasi, persepsi komunitas pembelajaran dan persepsi interaktivitas dalam e-learning pada motivasi belajar mahasiswa di masa pandemi. Jenis penelitian yang digunakan adalah penelitian kuantitatif. Sampel pada penelitian ini adalah mahasiswa univesitas negeri atau swasta di Semarang yang pernah menggunakan media pembelajaran E-learning pada periode April 2020 – Juli 2021. Pengumpulan data menggunakan kuesioner melalui media google form dengan jumlah data sebanyak 129. Dari hasil penelitian diketahui bahwa, terdapat pengaruh persepsi konten, persepsi antarmuka, persepsi umpan balik, persepsi personalisasi, persepsi komunitas pembelajaran dan persepsi interaktivitas dalam e-learning pada motivasi belajar mahasiswa di masa pandemi.
Pengaruh Persepsi Kemudahan, Persepsi Manfaat, Promosi E-Wallet dan Lingkungan Teman Sebaya terhadap Perilaku Konsumtif Mahasiswa
Authors: Miswanto Miswanto , Sidik Putri Arneta , Arrafi Mohamad Faiz
Published: April 2023

This study aims to examine the effect of perceived convenience, perceived benefits, e-wallet promotion, and peer environment on the consumer behavior of students using ShopeePay. The object of the research is students who use the ShopeePay e-wallet in various regions with primary data obtained from distributing questionnaires. The analytical method used is the convenience sampling method. The findings of this study indicate that (1) Perception of convenience does not have a positive effect on student consumptive behavior, (2) Perception of benefits does not have a positive effect on student consumptive behavior, (3) Promotion has a positive effect on student consumptive behavior, and (4) Peer environment has a positive effect on student consumptive behavior.
Pengaruh Good Corporate Governance Dan Konservatisme Akuntansi Terhadap Manajemen Laba
Authors: Maryati Sri , Yusnaini Yusnaini , Dwiantoro Arif
Published: April 2023

Tujuan dari penelitian ini adalah untuk menguji secara empiris Pengaruh Good Corporate Governance dan Konservatisme Akuntansi Terhadap Manajemen Laba. Good Corporate Governance pada penelitian ini mencakup komite audit, ukuran dewan komisaris, kepemilikan manajerial. Populasi dalam penelitian merupakan perusahaan manufaktur yang terdaptar di BEI tahun 2016-2020 dan Sampel dipilih menggunakan teknik purposive sampling diperoleh sebanyak 50 perusahaan yang memenuhi kriteria. Data dianalisis menggunakan  analisis regresi linera berganda dengan menggunakan program SPSS 25. Hasil penelitian menunjukkan bahwa komite audit tidak berpengaruh terhadap manajemen laba, namun ukuran dewan komisaris, kepemilikan manajerial, dan konservastisme akuntansi berpengaruh terhadap manajemen labaGood Corporate Governance, Conservatism, Earning management
Analisis Destination Brand Equity di Era New Normal
Authors: Wadyatenti Maria Angela Diva Vilanigrum
Published: April 2023

Tourism destination berkaitan dengan sebuah merek yang merupakan “transfer” dari prinsip-prinsip yang berhubungan dengan merek dari disiplin ilmu pemasaran namun secara spesifik pada konteks tourism. Kuatnya suatu destination brand tercermin dari ekuitas destination brand. Penelitian ini memperluas dan mengekspolorasi penerapan multidimensional CBBE dari dalam konteks pemasaran pariwisata. Tujuan dalam penelitian ini adalah mengembangkan kerangka destination brand equity dari perspektif CBBE yang mengeksplore destination brand awareness, destination brand image, destination perceived quality dan  destionation brand loyalty dalam mengukur destination brand equity. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan survey daring dari 245 pengunjung destinasi wisata Borobudur. Analisis data dan pengujian hipotesis menggunakan regresi linear berganda dengan SPSS 26. Hasil penelitian ini menunjukkan bahwa destination brand image, destination perceived quality dan destionation brand loyalty berpengaruh positif  terhadap destination brand equity, namun destionation brand awareness tidak mempengaruhi destination brand equity.
Peran Good Corporate Governance dalam Menurunkan Credit Risk pada Bank yang Go Public di Bursa Efek Indonesia
Authors: Virgantara Dika Zanuar , Mutamimah Mutamimah
Published: April 2023

This study aims to examine and analyze the role of good corporate governance in moderating the influence of the loan to deposit ratio, capital adequacy ratio, inflation and gross domestic product on the reduction of credit risk in banking companies that go public on the Indonesia Stock Exchange. The population in this study are all companies going public on the Indonesian Stock Exchange. The sampling technique used purposive sampling, with the criteria for banking companies going public in 2008-2021, so that 308 observations were obtained. The type of data is panel data which is a combination of cross section data and time series data, so the statistical technique uses E-views software. After passing the classic assumption test and conducting tests to choose the best results, the results show that the loan to deposit ratio has an effect on credit risk, but the capital adequacy ratio, inflation and gross domestic product have no effect on credit risk. In addition, GCG strengthens the influence of the loan to deposit ratio in reducing credit risk, but GCG actually weakens the influence of the capital adequacy ratio in reducing credit risk.
PEMANFAATAN LAHAN KOSONG DAN LAHAN PEKARANGAN RUMAH YANG BERBASIS RAMAH LINGKUNGAN
Authors: Aco Nasir Aco Nasir , Risnawati Risnawati , Pajri Pajri , Indri Indri , Gugun Gugun
Published: April 2023

Pemanfaatan lahan kosong dan pemanfaatan lahan pekarangan rumah yang berbasis ramah lingkungan merupakan suatu kegiatan yang dapat memberikan manfaat dalam memenuhi kebutuhan pangan sehari hari.Desa Amola merupakan salah satu desa di kecamatan binuang kabupaten polewali mandar dengan jumlah penduduk kurang lebih 1.850 jiwa.Denga luas wilayah kurang lebih 15.000 hektar.Desa amola berbatasan dengan  sebelah utara desa kaleok,seblah selatan desa paku,sebelah barat mirring dan sebelah timur berbatasan dengan perbatasan pinrang (Sulawesi selatan).Hampir setiap rumah di desa amola memiliki lahan kosong dan pekarangan rumah  yang belum dimanfaatkan .pekarang kosong tersebut dapat dimanfaatkan sebagai lahan budidaya sayuran.Metode pengabdian masyarakat yang digunakan adalah pemberdayaan petani dan ibu pkk melalui perencaaan pengembangan komodasi ,dan pendampingan pemanfaatan lahan kosong.Hasil yang diperoleh menunjukkan bahwa pelaksanaan program kkn di desa amola melalui kegiatan pemanfaatan lahan kosong dan pekaragan rumah tangga.Metode yang digunakan adalah eksperimen.Masyarakat memanfaatkan lahan kosong dan pemanfaatan lahan pekarangan rumah untuk ditanami dengan tanaman yang dikonsumsi sehari hari,seperti sayuran,biji bijian,dan umni umbian.Hasil dari eksperimen ini memperlihatkan bahwa pemanfaatkan lahan kosong akan memberikan manfaat bagi masyarakat berupa terpeliharannya lingkungan dan adanya ketersediaan pangan segar.
PROGRAM UNASMAN MEMBANGUN DESA MELALUI PENYULUHAN HIV/AIDS DAN NARKOBA UNTUK KALANGAN REMAJA DAN PELAJAR
Authors: Muin Rahmah , Misbahuddin Misbahuddin , Sukmawati Sukmawati
Published: April 2023

Program Unasman Membangun Desa (PUMD) Multimatik angkatan XXXV Universitas Al-asyariah Mandar Tahun 2022 dilaksanakan secara berkelompok oleh setiap mahasiswa untuk menciptakan produk-produk yang dapat dimanfaatkan atau dapat mengedukasi masyarakat sasaran. Desa Beroangin  Kecamatan Mapilli Kabupaten Polewali Mandar menjadi salah satu lokasi Program Unasman Membangun Desa (PUMD) Multimatik ini. Berdasarkan permasalahan desa yang telah diungkap sebelumnya penyuluhan untuk kalangan remaja dan pelajar sangat dibutuhkan. Dalam merancang kegiatan ini, terlebih dahulu menentukan konsep dalam hal ini mengintegrasikan dua program kerja yang akan dilaksanakan. Dalam pelaksanaan dua program ini di tujukan bagi masyarakat khususnya remaja dan pelajar. Media penyuluhan dan sosialisasi dapat meningkatkan kemampuan  pemahaman remaja dan pelajar terhadap dua program kerja yang kami laksanakan. Sosialisasi atau penyuluhan terhadap HIV/AIDS diharapkan dapat memberikan pemahaman tentang bahaya HIV/AIDS terhadap remaja dan pelajar yang ada di desa Beroangin. Penyuluhan Narkoba juga diharapkan dapat memberikan edukasi kepada masyarakat khususnya remaja dan pelajar tentang bagaimana cara mencegah agar tidak terpengaruh terhadap penyalah gunaan narkoba.