bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunologic tests in the diagnosis of candidiasis sensitization
Authors: Pazyuk E. A. , Lukashkov V. M. , Glushko N. I. , Bulatova I. V.
Published: March 2022

Currently, the Kazan Research Institute of EMR has developed Candida albicans allergen for the diagnosis of allergic diseases caused by sensitization to Candida fungi by means of skin allergy tests. In some cases, however, skin allergy tests alone cannot be used to determine whether fungal sensitization is present. There are diseases in which skin testing is contraindicated. It is necessary to develop in vitro tests that ensure complete harmlessness of specific diagnosis for the patient.
Nakayama — Rutkovsky operation in complex treatment of bronchial asthma
Authors: Duntsov G. V.
Published: March 2022

In recent decades, both in our country and abroad, a significant increase in the incidence of bronchial asthma in all age groups, its more severe course, increased mortality, large economic losses associated with temporary and permanent loss of ability to work have been noted. This disease attracts the attention of physicians of various specialties, including surgeons. More than 20 types of surgical interventions have been proposed for the surgical treatment of bronchial asthma; glomectomy with denervation of the sinocarotid reflexogenic zone, or Nakayama-Rutkovsky operation, is the most common among them. Its pathogenetic essence lies in the interruption of the pathological reflex pathway between the lungs and the respiratory center by surgical action on the intermediate link, which is the sinocarotid reflexogenic zone.
Clinical and immunologic changes in newborns in late toxicosis of pregnancy
Authors: Fazleeva L. K. , Romanova N. A. , Trofimova I. Sh.
Published: March 2022

The aim of this work was to study the features of humoral immunity in 198 newborns depending on the duration of maternal treatment during pregnancy for late toxicosis. Immunological changes were judged by the levels of serum immunoglobulins A, M, G and E, circulating immune complexes and by the activity of the kinin system.
Relationship of immunomorphological reactions in the tumor stroma and regional lymph nodes in cancer
Authors: Tsyplakov D. E.
Published: March 2022

Regional lymph nodes play an important role in anti-tumor protection, and changes in them have prognostic value. However, the barrier function of lymph nodes is not always sufficient to hold back and destroy malignant cells. And if in some cases the latter, getting into the lymph nodes, are subjected to destruction, in others - they reproduce unhindered, which leads to further spread of the tumor process.
Thermal imaging diagnosis of neuroosteofibrosis zones in rheumatoid arthritis patients
Authors: Salikhov I. G. , Storozhev A. L. , Khabirov R. A. , Salikhova A. I. , Mirumyants L. S.
Published: March 2022

The role of muscular system pathology in the clinical manifestation of rheumatoid arthritis is well known and confirmed by electromyographic, histological and histochemical studies. Clinically, muscle syndrome in rheumatoid arthritis is manifested by myalgia, myositis, muscle hypotrophy, as well as increased tone of periarticular muscles, painfulness in places of attachment of muscles to tendons, tendons to bones. When palpating the skeletal muscles located near the affected joint, we determined local areas of maximum painfulness (trigger zones), which corresponded to the areas of local muscle thickening (Mller, Cornelius). The term "neuroosteofibrosis," which is accepted in the literature, was proposed to denote such conditions.
All-Union Conference "Actual Problems of Hemostasis in Clinical Practice"
Authors: Voronina I. E. , Andreev S. V. , Ковалева T. N.
Published: March 2022

The conference was attended by therapists, surgeons, obstetricians, gynecologists, biochemists, pharmacologists, physiologists, and pathologists from Moscow, Leningrad, Kiev, Minsk, Kazan, Tbilisi, Novosibirsk, and other cities. Two plenary and five breakout sessions dealt with current issues of clinical hemostasiology. The increased interest of clinicians to the problems of hemostasis disorders is caused by the fact that at present the most important role of hemostasis disorders in the pathogenesis of most human diseases has been established.
Some socio-biological and hygienic aspects of natural feeding
Authors: Sultanova G. F. , Ivanova I. E.
Published: March 2022

In recent years, Soviet and foreign researchers have paid increasing attention to the study of socio-biological and hygienic factors influencing the duration of natural feeding. The influence of hereditary causes on the development of hypogalactia is insignificant, which is confirmed by its rapid growth in recent decades. Early transfer to artificial and mixed feeding is a gross violation of the evolutionary biological chain "pregnancy - birth - lactation" and often harms the health of the woman and child, violates the microclimate of the family. This prompts the study of the causes leading to hypogalactia and the search for new ways and methods of their elimination.
Screening of patients under 30 years of age with uterine myoma
Authors: Sabirov F. M. , Timofeeva T. I. , Talatina L. L. , Martynova O. F.
Published: March 2022

There are three groups of patients with uterine myoma during the follow-up examination. Group 1 includes women with asymptomatic myoma, and Group 2 includes myoma that exceeds the size of the uterus at 14 weeks' gestation, is accompanied by bleeding, pain, rapid growth, and squeezes neighboring organs. Women in these groups are to be followed up once every 3 months. If conservative therapy has no effect, surgery is resorted to. Group 3 includes patients with uterine myoma causing anemia, rapid growth, and dysfunction of adjacent organs. These women are hospitalized for further examination and decision on surgical treatment. In women of all three groups the mammary glands should be examined.
Aeroion therapy for lung diseases: indications and features of the technique
Authors: Kokosov A. N.
Published: March 2022

In the system of stage-rehabilitation treatment of patients with bronchial and pulmonary diseases in the period of rehabilitation the non-medicamental, in particular, physiotherapeutic influences having hypersensitizing effect and increasing nonspecific resistance of an organism have the basic value. A certain place among non-pharmacological means of rehabilitation treatment is occupied by aeroion therapy, the possibilities of which are still insufficiently used, which seems to be caused by the fact that practical doctors and healthcare organizers are not aware of the essence of aeroion therapy, its possibilities, indications for use and methods. This short report is intended to fill this gap.
Irina Nikolaevna Diakonova
Authors: Kamzeev V. D. , Sakhovsky P. I. , Matveeva T. V.
Published: March 2022

In May 1987, Professor Irina Nikolaevna Dyakonova, Head of the Department of Nervous Diseases of Kazan Institute for Advanced Training of Physicians, Doctor of Medical Sciences, celebrated her 70th birthday.
Metabolic basis of burn intoxication and ways of detoxification therapy
Authors: Lifshitz R. I.
Published: March 2022

The pathogenesis of burn toxemia is one of the central problems of combustiology. Due to the successes of antishock therapy, burn mortality is currently observed mainly not in the state of shock, but in the periods of toxemia and septicotoxemia. There is an urgent need to study the pathogenesis of endogenous intoxication after thermal injuries and develop the most promising ways of detoxification therapy. Clearly, this requires the solution of a number of interrelated issues: clarification of the nature of pathochemical reactions in relation to the function of various organs and systems, their dependence on the area and depth of the lesion, the nature of the toxic products that determine the changes occurring, and finally, the appropriate ways of their inactivation or removal from the body. Most of the above questions have been studied for a number of years by the staff of the Biochemistry Department of Chelyabinsk Medical Institute and the Regional Burn Center, which is the clinical base of the department.
Complex psychotherapy for patients with bronchial asthma and chronic obstructive bronchitis
Authors: Salikhov I. G. , Yulmeteva D. G. , Zhilyaev A. G.
Published: March 2022

We have analyzed the effectiveness of psychotherapy for patients with bronchial asthma and chronic obstructive bronchitis in general hospital conditions.There were 104 patients under observation. 70 patients (27 men and 43 women) at the age of 16-62 years formed the main group. Bronchial asthma was diagnosed in 42 patients, infection-dependent and mixed variants with a severe course, in 28 patients - chronic obstructive bronchitis. The basic disease lasted from 1,5 to 28 years and was complicated by pulmonary emphysema in 9 patients, respiratory failure of I-II degree in 58 patients; 9 persons became disabled.
Treatment of patients with open fractures of long tubular bones with a new external fixation device
Authors: Aidarov R. B.
Published: March 2022

The problem of treatment of patients with open metadiaphyseal fractures of long tubular bones is relevant due to the increasing frequency of these injuries and their particular severity.From 1978 to 1983 there were 213 patients with open metadiaphyseal fractures of long tubular bones in the traumatology departments of the emergency hospital. There were 175 (82%) men and 38 (18%) women. The majority (72.7%) were persons of the most employable age, from 21 to 50 years old. There were 45 (21.4%) persons admitted under the influence of alcohol.
Treatment of posttraumatic osteomyelitis of long tubular bones
Authors: Khabirova G. F. , Zakirov Yu. A.
Published: March 2022

The treatment of osteomyelitis of the long tubular bones is a complex problem of traumatology and orthopedics, as well as of purulent surgery. The difficulties of its solution are associated with extensive bone lesions, which causes frequent relapses of this severe disease and leads patients to long-term disability, permanent disability, and frequent and often traumatic surgeries.
Treatment of idiopathic osteonecrosis of the femoral head
Authors: Prokhorov V. P.
Published: March 2022

Idiopathic osteonecrosis of the femoral head in adults is one of the most common degenerative-dystrophic diseases of the hip joint, with a clear upward trend. Affecting individuals of relatively young age, with especially frequent bilateral development (up to 50% of cases), this pathology leads the most able-bodied patients to severe and irreversible disability. Therefore, the nature of idiopathic osteonecrosis and its treatment remain among the most pressing problems in modern orthopedics and in clinical medicine in general.
Outpatient treatment of brachial scapular periarthritis with hydrocortisone combined with hypothermia
Authors: Ilyinsky I. S. , Bekmachev V. I.
Published: March 2022

Periarthritis of the shoulder-blade arises as a reactive inflammatory process after trauma or from primary inflammation of the joint pouch. The treatment of this disease is a difficult task. Conservative methods are not always effective, and surgical methods are not widespread. Some authors have achieved success with hydrocortisone injections.
Headaches with temporomandibular joint dysfunction
Authors: Nasibullin G. G. , Zizevskiy S. A.
Published: March 2022

Headache as a concomitant symptom in functional diseases of the temporomandibular joint, combined with pain in the joint and masticatory muscles, is quite common. Our clinical observations also indicate a combination of temporomandibular joint dysfunction with headaches.
Readers about the restructuring of the "Kazan Medical Journal"
Authors: Fatkullin F. Kh.
Published: March 2022

If we briefly formulate the credo of the Kazan Medical Journal, it is encapsulated in its subtitle: a scientific and practical journal for physicians. Orientation to the practicing physician, a generalist is a traditional feature of the journal since the renewal of its publication in 1921 and up to the present day. The journal's content is determined primarily by the needs of health care; its main reader and correspondent is the attending or sanitary doctor, who carries out the daily care of the health of Soviet people.
G. N. Drannik, Ya. M. Yena, T. V. Varetskaya. Products of fibrin/fibrinogen cleavage in pathological processes (biochemical and clinical aspects). Kiev, Zdorov'ya, 1987.
Authors: Zubairov D. M. , Litvinov R. I.
Published: March 2022

One of the biochemical indicators objectively characterizing the state of hemostasis is the level of fibrin and fibrinogen cleavage products in blood, which are formed, as a rule, as a result of intravascular fibrin formation with simultaneous or subsequent activation of fibrinolytic system, accompanied by appearance of proteolytic enzyme plasmin. Plasmin splits (degrades) the formed fibrin or (to a lesser extent) fibrinogen, which leads to the appearance of more or less large protein "fragments" in the bloodstream, called products of fibrin degradation. Some of them are unable to clot and can be detected in serum after clot separation. Thus, the detection of fibrin degradation products always indicates intravascular activation of hemocoagulation and fibrinolysis systems.
Preparation of human immunoglobulin against hemorrhagic fever virus with renal syndrome
Authors: Gavrilovskaya I. N. , Bogdanova S. B. , Gorbachkova E. A. , Chumakov M. P. , Apekina N. S. , Linev M. B. , Myasnikov Yu. A. , Mukhutdinov I. Z. , Potapov V. S. , Boyko V. A. , Mukhutdinova R. G. , Yagnova L. V. , Kamalov F. Z.
Published: March 2022

Hemorrhagic fever with renal syndrome (HFRS) is a viral zoonotic natural focal infectious disease of humans and is particularly widespread in the forest areas of the Urals and Middle Volga region. In recent years, methods have been developed and put into practice for indication of infection in rodent hosts of HFRS virus and for serodiagnosis of human HFRS.
Efficiency of a short course of prednisolone in the treatment of severe viral hepatitis
Authors: Bashirova D. K. , Mukhlisova G. F. , Zvereva L. P.
Published: March 2022

In recent years, there have been differences in views on glucocorticosteroid therapy (GCS) in patients with acute viral hepatitis. Disagreement arose due to reports about the lack of significant difference in the outcomes of hepatic coma in patients treated and untreated with GCS, about the frequency of relapses and transformation of the process into a chronic form during therapy with these drugs.
The significance of anatomical asymmetry for injectable treatment of acute conditions
Authors: Ibatullin I. A.
Published: March 2022

In the acute care clinic, the main place in the treatment of patients is occupied by injection methods of drug administration to the upper extremities. This does not take into account the different characteristics of the pathology for which these measures are performed. Thus, in the decompensated stage, they can lead to death or worsen the condition of the patient.
Intensive care of victims with multiple and combined injuries
Authors: Valeeva S. M.
Published: March 2022

The aim of the present study was to investigate the peculiarities of the course of acute traumatic disease with multiple and combined injuries and to develop pathogenetically substantiated corrective therapy. The patients treated in the intensive care unit from 1983 till 1986 were examined. 110 (18,8%) out of 584 patients had multiple and combined injuries. There were 87 men and 23 women.
Analysis of causes and measures to reduce early neonatal mortality after cesarean section
Authors: Akhmadeeva E. N. , Kulavsky V. A.
Published: March 2022

We have performed a selective expert evaluation of 111 cases of lethal outcomes of newborns delivered by cesarean section. In the total number of operations performed during the study period, the number of neonates who died by means of this surgical intervention was 5.8%. The incidence of infant deaths after cesarean section in the early neonatal period among all neonatal deaths during the same period reached 24.8%. The high proportion of children delivered by cesarean section in the structure of early neonatal mortality indicates the relevance and practical significance of studying the causes of infant mortality in this group.
Changes in the brain microcirculatory bed in craniocerebral trauma
Authors: Krylov V. E. , Ibatullin M. M. , Valeev E. K. , Padiryakov V. N.
Published: March 2022

The microcirculatory bed is an important department of the circulatory system and determines not only the state of peripheral hemodynamics but also the trophic function of the organs. Microcirculatory bed, including arterioles, precapillaries, capillaries, venules, arteriolovenular anastomoses, constitutes 90% of all blood vessels [9, 18J. Arterioles - long meandering vessels 30-40 in diameter - are divided into terminal and mesarterioles. Precapillaries are 15-20 in diameter and regulate blood flow to true capillaries. Arterioles and precapillaries perform a transport function, delivering nutrients to the organ. Excretion of metabolic products from the organ occurs only in the capillary channel. Blood flow in capillaries depends on the activity of precapillary sphincters. Capillaries are usually straight and their wall lacks muscular elements. The appearance of tortuosity indicates damage to the capillary bed and impaired blood flow in it.
Causes of lethal outcomes after surgery in patients with congenital and acquired suppurative pulmonary diseases
Authors: Pavlunin A. V.
Published: March 2022

The aim of this work was to study the causes of lethal outcomes during surgeries in patients with chronic nonspecific lung diseases (CNLS) depending on the nature of the disease, volume and peculiarities of the surgical intervention. There were performed 1751 surgeries in 1631 patients with CPPS from 1971 till 1986. 70 (4.3%) people died of severe postoperative complications during the hospital stay.
Biphasic rupture of the liver and gallbladder
Authors: Ilyinsky I. S.
Published: March 2022

Closed liver injuries are rare and more common in men. Preoperative diagnosis is difficult and mortality is high. Liver injuries are often detected during surgery or at autopsy. Considering the rarity of this pathology and difficulties in diagnosis, we decided to share our observation.
Integral body rheography in the complex diagnosis of sepsis in gynecological patients
Authors: Kostyuchek D. F. , Bagramyantsev E. V.
Published: March 2022

We used integral body rheography (IRGT) to assess central hemodynamics in 10 patients with obstetric-gynecological sepsis. Eight women developed sepsis as a result of an out-of-hospital infectious abortion at 7 to 26 weeks' gestation, and two - as a complication of gynecological surgery. Septicemia occurred in 7 patients, septicaemia - in 3, septic shock - in 2, in 1 patient it was complicated by acute renal failure; peritonitis was diagnosed in 1 woman.
Influence of mast cell response and some vasoactive substances on the blood microcirculation of lymph nodes regional to a cancerous tumor
Authors: Tsyplakov D. E. , Ziganshina L. E.
Published: March 2022

Regional lymph nodes from 70 cancer patients (42 men, 28 women, mean age 54.9 years) received during gastric, intestinal, esophageal, lung, and breast cancer surgeries were studied.
Some ways to improve the effectiveness of emergency treatment of the most frequent extreme conditions in the practice of a general practitioner
Authors: Leshchinsky L. A. , Valeeva R. M. , Pimenov L. T. , Chaly P. I.
Published: March 2022

We have the results of observations of 2500 patients with myocardial infarction treated in the clinical cardiology dispensary of the Udmurt ASSR in 1981-1986. The effectiveness of resuscitation measures in clinical death on the basis of myocardial infarction in recent years is almost at the same level (46.1%-57.4% in different years).
The importance of predisposition in the development and diagnosis of kidney disease
Authors: Maltsev S. V. , Davydov V. M.
Published: March 2022

During 1983-1986, 1,896 children with urinary system diseases were examined in the nephrology department. Application of a wide complex of clinical, laboratory and radiological methods allowed to diagnose 20 different variants of renal pathology within 12 nosological groups. Acquired nephropathies accounted for 81% in the total structure of kidney diseases in children.
Effect of different methods of artificial lung ventilation on hemodynamic indices in newborns and infants during anesthesia and surgery
Authors: Shalimov V. N. , Zhavoronkov V. F.
Published: March 2022

We observed 52 children aged from one day to 5 months who underwent surgery for various surgical diseases (atresia of the anus and rectum, high intestinal obstruction, pylorostenosis, intestinal intussusception, hemangiomas of various body regions, etc.). No significant abnormalities of the pulmonary and cardiac system were found during the preoperative examination. All children depending on the method of artificial ventilation were divided into three groups.
Structure of chronic inflammatory kidney diseases in workers of oil refineries
Authors: Yanbaev B. Sh.
Published: March 2022

We determined the prevalence of chronic inflammatory kidney diseases by a continuous staged examination of 8264 workers and employees of oil refineries: 4051 (49.0%) women and 4213 (51.0%) men aged 20-60 years. At the first stage we conducted a mass cumulative examination of the workers using a screening test for proteinuria, blood pressure measurement, and a questionnaire. At the second stage, persons with suspected kidney disease were examined in an outpatient clinic - Nechiporenko urinalysis was performed, the degree of bacteriuria was determined, and an examination with the history was made. Patients were consulted by specialists (gynecologist, urologist, otorhinolaryngologist, dentist, oculist). The third stage was an in-depth examination of the identified patients in a specialized municipal nephrological department in order to establish the diagnosis of nephropathy. The latter included a detailed interview with occupational history, detailed clinical examination, isotopic renography, and, if indicated, excretory urography.
Content of fucose, neutral hexoses and sialic acids in duodenal juice in duodenal ulcer and chronic acalculous cholecystitis
Authors: Rabinovich P. D. , Belova I. M.
Published: March 2022

The aim of our work was to estimate the state of fucoglycoprotein and sialoglycoprotein secretion in duodenal ulcer disease. We examined 125 patients aged from 16 to 60 years divided into five groups. The 1st group included 29 patients (17 men and 12 women) with acute exacerbation of peptic ulcer disease; the 2nd group included 20 patients (11 men and 9 women) with moderate exacerbation of the disease; the 3rd group included 21 patients (11 men and 10 women) with clinical remission; the 4th group included 38 patients (18 men and 20 women) with exacerbation of chronic acute cholelithiasis. The 5th control group included 17 (10 men and 7 women) healthy people. The duration of the disease varied from one year to 20 years.
Diagnosis and treatment of esophageal esophagus
Authors: Sakhautdinov V. G. , Gantsev Sh. Kh.
Published: March 2022

We observed 5 patients with isolated inguinal prolapse (4 men and 1 woman); age ranged from 28 to 61 years old.) Four patients had a history of inguinal hernia surgeries, and one patient had herniotomy and appendectomy. The duration of the preceding surgeries before the occurrence of a large omental prolapse ranged from 1 to 4 years.
Cylinder pencil case for sterilization and storage of spokes
Authors: Kovalev E. V. , Gorlov S. A.
Published: March 2022

We propose a cylinder-pen for sterilization and storage of spokes used for osteosynthesis. The device corresponds to the sizes of spokes produced by the medical industry and consists of two hollow cylinders: an external one (with a sealing lid) and an internal one. The latter holds 40 spokes and has 5 mm diameter holes in its walls which allow the free flow of boiling water. Once the sterilization of both cylinders is completed, the inner one (containing the spokes) is sealed observing all aseptic rules.
Prevention and treatment of postpartum hypotonic bleeding
Authors: Sidorova I. S. , Botvin M. A. , Ryazanova E. S.
Published: March 2022

Obstetric bleeding continues to be one of the most severe complications of pregnancy and childbirth. According to the statistical data of obstetric institutions of the USSR and foreign countries, the frequency of hypotensive bleeding has tended to increase in recent years. Over the past decades, they inevitably occupy one of the first places among the causes of maternal mortality. All pregnant women at risk of hypotonic bleeding should be hospitalized at 38 weeks of gestation for comprehensive prenatal care, including the administration of estrogen, glucose, ascorbic acid, antispasmodic and sedatives.
All-Union Conference "Surgery of Human Echinococcosis"
Authors: Kuznetsov V. A.
Published: March 2022

Two aspects of the problem were discussed at the All-Union Conference with participation of representatives from other countries: "Epidemiology and Diagnostics of Echinococcosis" and "Surgical Treatment of Human Echinococcosis". State significance of this problem is explained by high frequency of primary forms of echinococcosis, complications, relapses and polyorganic pathology (B.V. Petrovsky, O.B. Milonov, Moscow; L.S. Yarotsky, V.B. Martynenko, Moscow; K. Schmidt, GDR; T. Stoyanov, Bulgaria).
VII All-Union Conference "Tasks of Post-Diploma Training of Health Care Managers to Implement the Main Directions of Improving Public Health Protection"
Authors: Nizamov I. G.
Published: March 2022

The conference was attended by heads of departments of social hygiene and organization of health care of institutes and faculties of advanced training of doctors (at medical universities), economists, mathematicians, as well as heads of health care bodies and institutions.
Hemocoagulation state under conditions of transfusion of blood, its components and preparations
Authors: Gorbunova N. A. , Lagutina N. Ya.
Published: March 2022

One of the methods of therapy, widespread in all areas of clinical medicine, is blood transfusion. The volume of blood transfusions varies, sometimes reaching several liters, especially in cardiovascular surgery and obstetrics and gynecological practice. Numerous experimental and clinical studies have established that the main, replacement function of blood transfusion is most pronounced in cases of acute blood loss, hemorrhagic shock and is due to the interrelated functioning of individual blood components of the recipient and donor.
Effect of a preparation of medical leeches (Hirudo medicinalis) on phagocytosis and the complement system
Authors: Baskova I. P. , Nikonov G. I. , Mirkamalova E. G. , Zinchenko V. V. , Kozlov L. V.
Published: March 2022

Except such known inhibitors of proteolytic enzymes, as hirudin, bdellins and eglins, and also hyaluronidase enzyme, by us in a secretion of salivary glands of medical leeches the new enzyme destabilase which breaks isopeptide bonds in stabilized fibrin and having thrombolytic action, inhibitor of blood plasma kallikrein and prostanoids, on a spectrum of action similar to prostacycline and its stable analogues have been found. We show that the secret of leeches irrespective of presence in it hirudin suppresses platelet-vascular hemostasis, interfering adhesion of platelets on a surface of collagen and the aggregation of the platelets stimulated by inductors of various nature, by activation of adenylate cyclase of membranes of platelets [3]. Irrespective of the presence of hirudin, the secret blocks the contact stage of the internal mechanism of blood coagulation by inhibiting blood plasma kallikrein and Hagemann factor.
Biochemical and functional features of blood plates in myeloproliferative diseases
Authors: Egorova V. A. , Belyazo O. E. , Shcherbakova E. G. , Blinov M. N. , Fedorova Z. D.
Published: March 2022

The aim of this work was to study the relationship between changes in blood platelet sialic acid levels and adenine nucleotide pool regulation with the parameters of platelet hemostasis (adhesive-aggregation and retractile capacity of blood plates) in chronic myeloleukemia and idiopathic myelofibrosis. The studies were performed on platelets of healthy subjects (20), patients with chronic myeloleukemia (14) and idiopathic myelofibrosis (11) with advanced clinical manifestations.
Hemosorption treatment of rheumatoid arthritis patients
Authors: Trusov V. V. , Bazhenov A. N. , Nasachev A. A.
Published: March 2022

Hemosorption as a component of complex therapy was included in the treatment of 47 patients with reliable rheumatoid arthritis. Women predominated among the patients (35 out of 47). The patients were aged from 23 to 60 years (under 40 years - 19, over 40 - 28). Seventeen people had been ill for 1 to 5 years, 24 for 6 to 10 years, and 6 for 11 to 15 years. The disease progressed rapidly in 1 of the patients and slowly in 36 of them. Grade II process activity was found in 34 patients, and grade III - in 13 patients. Radiological stage I-II of the disease was detected in 16 patients, in 28 patients - III, in 3 - IV. I-II degree and 6 - III degree of functional insufficiency of joints were diagnosed in 41 patients. The seropositive variant of rheumatoid arthritis was found in 28 patients and seronegative - in 19 patients. All patients had oligopolyarthritis; 25 of 47 patients had systemic manifestations.
Stromal fibroblasts and invasive cancer growth
Authors: Petrov S. B.
Published: March 2022

Stromal fibroblasts from 230 cancerous tumors of different localization were studied. Fibroblasts were located in the stroma of cancerous tumors relatively uniformly - on average 2430.9 133.7 per 1 mm2 stroma, but since the stroma occupied only a part of tumors, the number of fibroblasts per 1 mm2 histological preparation of neoplasm was somewhat lower and varied from 58.1 to 2772.0 (on average 1114.4 107.8), and in some cases fibroblasts were the prevailing cell type. The axial orientation of these stromal cells, especially in the areas of mature stroma, mostly coincided with the direction of collagen fiber bundles, and in the areas of edematous and disorganized connective tissue was often chaotic.
Sulfhydryl group content in dry plasma of pregnant, parturient, and postpartum women
Authors: Magomedbekov A. G.
Published: March 2022

Sulfhydryl groups were detected in the dry plasma of 63 first-born and 49 second-born healthy women at 38-40 weeks of pregnancy, during the first and second periods of labor, at 2 hours after delivery, and on the 3rd and 5th days after delivery. Ten healthy non-pregnant women of childbearing age constituted the control group.
Acute fatty liver dystrophy and pregnancy
Authors: Bashirova D. K. , Enaleeva D. Sh. , Tsaregorodtsev A. D. , Gilyazutdinova Z. Sh. , Sadykov B. G. , Miftakhova F. A. , Kolosova N. A. , Olkhova M. G. , Fatkullov M. S.
Published: March 2022

The etiology and pathogenesis of acute liver obesity in pregnancy are poorly understood. It is believed that this severe complication of pregnancy is caused by a lack of protein nutrition, depression of protein synthesis. Clinically, the disease runs as fulminant (malignant) hepatitis.
Experience of anonymous treatment for chronic alcoholics and abusers
Authors: Klassen I. A. , Nikolskaya L. D.
Published: March 2022

Anonymous treatment of alcohol abusers and chronic alcoholics as one of the forms of outpatient narcological care for the population is becoming increasingly important for patients with preserved social status. From the beginning of 1986, an anonymous treatment room began to function in our dispensary. Clients can receive help and advice five days a week, three of them in the evenings until 10 p.m. The anonymous treatment office has a room with a file cabinet for individual doctor's appointments, psychotherapy and treatment rooms, and a waiting room.
Hygienic assessment of the daily routine of children in preparatory groups of preschools
Authors: Muratova D. A.
Published: March 2022

Educational work carried out in classes in preschools is crucial to the mental development of children, being at this stage the main form of preparing children for school.
Diagnostic value of high-density lipoprotein cholesterol determination in alcoholism
Authors: Zemlyanova L. I. , Milkina T. A.
Published: March 2022

The aim of this work was to study the dynamics of blood lipid content in alcoholism. We examined 41 patients with stage II alcoholism and 10 healthy men (control group). The age of the patients ranged from 23 to 55 years. Blood for the study was taken in the morning on an empty stomach at the admission of patients and after 12 days of treatment in LTP.
X-ray endobiliary interventions for cholestasis of different etiology
Authors: Kondrashin S. A.
Published: March 2022

Currently, our experience includes more than 40 percutaneous transhepatic cholangiographies using ultrathin Hiba needles and stiletto catheters, during which various X-ray endobiliary interventions were performed. Their standard program through the needle included cholangiography, washing of biliary tracts with physiological solution, extraction of contrast substance and bile after the study, intraductal antibiotic therapy, administration of antispasmodics.
Pregnancy gestosis and polyhydramnios
Authors: Yartseva M. A.
Published: March 2022

In the available literature, we did not find any works that would reveal the peculiarities of the course of gestosis in pregnant women with polyhydramnios. In addition, it would be interesting to study the incidence of gestosis and its development, taking into account the possible causes of amniotic fluid, to assess the outcome of pregnancy for the mother and fetus when these complications are combined. A total of 161 pregnant women with abundant amniotic fluid were followed up, and 142 of them (88.2%) had gestosis. Pregnant women aged 20 to 30 years comprised the main population (61.3%).
Causes of adverse course of acute appendicitis in children
Authors: Savvidi I. V.
Published: March 2022

We analyzed 220 observations of complicated forms of acute appendicitis in children and medical histories of 22 patients who died of the disease. The causes of the adverse course of acute appendicitis were studied at three stages of medical care: 1) at the level of pediatric areas, ambulance services, and somatic pediatric departments, 2) in the general surgical departments of the CDC, and 3) in specialized pediatric surgical departments.
Organizational and managerial aspects of strengthening the preventive orientation of Soviet health care
Authors: Tsaregorodtsev A. D. , Vakhitov Sh. M.
Published: March 2022

The XXVII Congress of the CPSU outlined the strategic course of the development of our country. Its main feature is a policy of acceleration, which consists not only in increasing the rate of economic growth, but also in improving social relations, updating the forms and methods of work, overcoming inertia, further developing the creativity of the masses.
Changes in immune reactivity in patients with complicated forms of diabetes mellitus during hemosorption
Authors: Veretennikov S. V.
Published: March 2022

Currently, it can be considered established that diabetes mellitus is accompanied by significant changes in the immune system. However, the literature data characterizing them are not only ambiguous, but also contradictory. There are reports on the likely role of changes in humoral reactivity in the pathogenesis of a number of complications of diabetes mellitus. Previously, there were reports on the use of hemosorption in patients with generalized microangiopathies, but the impact of hemosorption on the immune system in patients with complicated forms of diabetes has not been studied.
Criteria for Evaluation and Prediction of Hemodynamic Status and Physical Performance in Hypertension
Authors: Komissarov V. A.
Published: March 2022

The aim of the present study was to develop criteria for quantitative assessment of the functional state of the circulatory apparatus and physical performance in hypertensive patients according to the indices of cardio- and hemodynamics without ergometric study. The necessity of this study was dictated by the following reasons: firstly, the average hemodynamic pressure increases as the disease progresses, and during physical activity its growth slightly outpaces the increase of heart rate. Secondly, reflecting peripheral vascular permeability, it determines postload and left ventricular myocardial tension. Thirdly, dissociation of proper and actual values of left ventricular isovolumic contraction period (with increasing actual) increases with disease progression. Fourthly, the formation of hypertrophy, disturbance of metabolic processes in myocardium, development of cardiosclerosis lead to prolongation of asynchronous myocardial contraction period, prolongation of which was found by many authors in different stages of hypertension.
Disorders in the system of nonspecific resistance in diabetic patients and their pharmacological correction
Authors: Valeeva F. V.
Published: March 2022

Complications of infectious and inflammatory nature in patients with diabetes mellitus often determine the prognosis of the disease. In their development, along with disturbed metabolic processes, a known role is played by changes in nonspecific protection and immunological reactivity mechanisms of the body. The study of the state of humoral and cellular immunity in diabetes mellitus is due to the fact that the accompanying infectious-inflammatory process is characterized by a more severe course and difficult to treat.
Clinic and treatment of tetanus in adults
Authors: Gelfand L. L. , Mikheev S. A. , Gabidullina I. Kh. , Stepanova N. V.
Published: March 2022

Against the background of constant immunization of the population against tetanus, the incidence of this infection has decreased, but the mortality rate remains high.We analyzed 13 case histories of tetanus patients. In all cases the disease was generalized. Among the patients there were 9 men; 10 patients were rural residents. The age of the patients ranged from 21 to 47 years, indicating their insufficient prophylactic immunization. The disease was more often observed in April-October, i.e. during the agricultural season.
A life shackled by disease
Authors: Gashkovtsova G.
Published: March 2022

A young healthy person sees life as a long, promising road that he walks in search of his place in family, work, and society. He knows that there are serious and life-threatening illnesses that are difficult or even impossible to live with. From popular science or health education books and articles he has learned a rudimentary knowledge of the presence and prevalence of serious diseases that plague the civilized world. However, the fullness of life, the daily troubles and joys have their effect in the sense that one, except for personal professional interests, does not think more deeply about the world of the sick. One can only wish that one's journey through life will not be overshadowed by illness and that life, uncomplicated by illness, will pass according to expectation, ending many years later in physiological old age.
Some New Opportunities in the Treatment of Patients with Atherosclerosis
Authors: Vogralik V. G. , Saltseva M. T. , Vogralik M. V. , Amineva I. V. , Merinova I. V. , Runova A. A.
Published: March 2022

According to our deep conviction, measures to prevent, detect and treat atherosclerosis should be largely reoriented to the preclinical period of the disease and include correction, including non-medication, of metabolic disorders, elimination of other avoidable endogenous and exogenous risk factors for atherosclerosis, and primarily hyperlipidemia.
To the diagnosis of pre-disease in smokers
Authors: Shcherbatenko L. A. , Andreev V. M. , Zhungin P. D. , Pyrgar D. P.
Published: March 2022

Smoking is a risk factor for many diseases. In particular, it leads to the development of chronic bronchitis and its complications. However, in spite of the urgency of the research of cardiorespiratory system state in smokers, there are almost no data in the literature about the complex study of this system in this contingent. The aim of this work is to elucidate the mechanisms of early changes in the cardiorespiratory system and to develop methods for their diagnostics in smokers who consider themselves healthy. 325 smokers and 197 non-smokers were examined. Their medical history was studied, ECG, fluoro- and spirography (GEL, SPHF, Votchal-Tiffno index) were performed. Smokers considered themselves healthy, they did not have any complaints.
Prevention of occupational injuries among porcelain factory workers
Authors: Seyukov I. N.
Published: March 2022

We studied the injury rate among the workers of the Bugulma Porcelain Factory in 1982- 1987, taking into account the working conditions of the workers. The peculiarities of production at the plant include tedious, monotonous work on the conveyor belt at high temperature. The factory exists for 13 years. The young age of the workers - from 18 to 40 years - also draws attention.
Analysis of craniocerebral injuries in Bugulma district for 1976-1986
Authors: Shamsullin R. V.
Published: March 2022

In the area with a population of 106,000 people in 1976-1986, there was an upward trend in the frequency of craniocerebral injuries. The ratio of the number of men and women with craniocerebral injuries by years was as follows: men - 55-58%, women - 42-45%. The frequency of cranial and brain injuries increases in men at the age of 30-50 years, and in women at the age of 50 years.
Treatment of victims with closed diaphyseal fractures of the femur in combination with craniocerebral trauma
Authors: Prokopiev N. Ya.
Published: March 2022

The present report is based on observations of 103 victims with closed fractures of the diaphysis of the femur combined with craniocerebral trauma. There were 89 men and 14 women. Compression of the brain by intracranial hematoma was diagnosed in 2 persons. Industrial injuries were registered in 16.5% of the victims, road traffic injuries in 69.9%, household injuries in 13.6%. In a state of alcoholic intoxication 23.3% of the victims were injured. In the state of traumatic shock 37.8% of the patients were admitted.
Middle ear cancer developed against the background of chronic purulent otitis media
Authors: Bobrov V. M.
Published: March 2022

Despite significant advances in the treatment of cancer patients in recent years, the diagnosis and treatment of malignant neoplasms of the middle ear remain very difficult. In part, this can be explained by the difficulty of recognizing cancer in its early stages and by the late seeking of medical help by patients.We consider it possible to present our own observation.
175th anniversary of Kazan Medical Institute
Authors: Khamitov Kh. S. , Galiullin A. N.
Published: March 2022

In the acts on founding a university in Kazan - the affirmative charter and statute, signed on November 5, 1804, among its four branches was included the branch of medical or medical sciences, but the opening of the medical faculty took place only on May 14, 1814. The process of forming the faculty, its development, and scientific and pedagogical work initially proceeded under difficult conditions. For a long time the faculty had no base of its own. The funds allocated by the government were quite insignificant. The Faculty had to pass especially hard tests in those years when the university was practically ruled by the reactionary and obscurantist M.L. Magnitsky. The medical faculty was then deprived of almost all of its professors. The few anatomical preparations by order of M. L. Magnitsky were buried in the cemetery. But even in these very unfavorable conditions new progressive forces were maturing in the University. In 1826 the rector of the University became a brilliant scientist and teacher N.I. Lobachevsky. He gathered around himself a nucleus of talented, creative and progressive scholars. Under his direct supervision the main institutions of medical faculty were built: anatomic theater, clinic buildings.
Clinical and pathogenetic aspects of viral hepatitis B
Authors: Sorinson S. N.
Published: March 2022

Viral hepatitis B is one of the key unsolved problems of modern medicine and is of great interest for clinicians of different profiles. Relevance of the problem is confirmed by high non-decreasing morbidity, possibility of severe course with the threat of fatal outcome, development of chronic forms of the disease, absence of reliable methods of etiotropic therapy. The study of hepatitis B became possible based on the verification of the diagnosis through the indication of specific markers of the virus, in particular its surface antigen (HBsAg). In our practice we have consistently used first-generation methods, firstly gel precipitation reaction (GPR) and counter immunoelectrophoresis (CEP), and later the highly sensitive methods, reverse passive hemagglutination reaction (ROPGA) and enzyme immunoassay (ELISA).
Functional state of hypothalamic-pituitary-adrenal system in patients with hemorrhagic fever with renal syndrome
Authors: Gelfand L. L. , Zaripov R. A. , Begicheva E. V.
Published: March 2022

The aim of our work was to study the state of hypothalamic-pituitary-adrenal system in patients with GLPS in comparison with electrolyte metabolism parameters depending on the period and severity of the disease. Twenty-four patients with GLPS, aged 16 to 53 years, were under observation. Most of them were young (23-24 years old). There were 19 men and 5 women. The diagnosis was made on the basis of clinical, epidemiological and laboratory data.
Borderline neuropsychiatric disorders in pregnancy
Authors: Mendelevich D. M. , Sakharov E. A.
Published: March 2022

Modern research in the field of psychosomatic medicine reveals a steady increase in interest in borderline neuropsychiatric disorders occurring during pregnancy. As evidenced by numerous literature sources, to date, there is no clarity on the issue of clinical features of borderline neuropsychiatric disorders in pregnant women. Domestic authors have considered these disorders only as part of the toxicosis of pregnant women, although many researchers have emphasized the fact that borderline neuropsychiatric disorders may develop in this population in addition to toxicosis.
Surgical treatment of patients with adenoma of the prostate in conditions of CRH
Authors: Petrov V. I.
Published: March 2022

There is a 60-bed urological department in Nizhnekamsk Central Regional Hospital. For 10 years it has been an interdistrict center, Mamadyshsky, Menzelinsky and Zainsky districts are attached to it. From 1981 to 1986 the department performed 545 adenomectomies of the prostate. (64,4%) patients were operated on one-stage. 194 (35.6%) patients (mostly patients from attached areas) required a two-stage adenomectomy. Patients were admitted with cystostomies placed a month or more ago. Seven (1.3%) patients died after the operation.
Infusion therapy for purulent-septic diseases in obstetrics and gynecology practice
Authors: Mosharev V. A. , Mikhailova L. G. , Ozerets I. A.
Published: March 2022

We present the results of treatment of patients aged 20 to 40 years with infected miscarriages complicated by metoendometritis and sepsis, with purulent mesenteric diseases of the uterine appendages and peritonitis.Patients in the 1st group (20 people) received hemodez along with the usual complex therapy; in the 2nd group (30 people) - polydesis. The case histories of 12 patients (Group 3) with similar pathological processes who were not prescribed detoxifying blood substitutes were analyzed for control purposes.