bluuebunny/crossref_metadata_2025 huggingface dataset:
Ipsilateral transradial access in transarterial embolization of upper extremity bony metastases
Authors: Pan Patrick , Lee Edward Wolfgang , Eghbalieh Navid , Trieu Harry
Published: August 2018

Transarterial embolization of bone tumors is effective in both decreasing intraoperative hemorrhage and alleviating symptoms. Transradial access has been associated with a lower risk of access site complications when compared to transfemoral access. Three cases of transarterial embolization of bony metastases in the upper extremity and shoulder girdle were performed with an ipsilateral transradial access. In each case, significant decrease in tumor blush was noted after embolization, and no auxiliary access site was needed. Positive outcomes were observed in all three patients, including successful subsequent surgery without significant hemorrhage and notable post-procedural pain reduction.
Bayesian Classification of Proteomics Biomarkers from Selected Reaction Monitoring Data using an Approximate Bayesian Computation-Markov Chain Monte Carlo Approach
Authors: Nagaraja Kashyap , Braga-Neto Ulisses
Published: August 2018

Selected reaction monitoring (SRM) has become one of the main methods for low-mass-range–targeted proteomics by mass spectrometry (MS). However, in most SRM-MS biomarker validation studies, the sample size is very small, and in particular smaller than the number of proteins measured in the experiment. Moreover, the data can be noisy due to a low number of ions detected per peptide by the instrument. In this article, those issues are addressed by a model-based Bayesian method for classification of SRM-MS data. The methodology is likelihood-free, using approximate Bayesian computation implemented via a Markov chain Monte Carlo procedure and a kernel-based Optimal Bayesian Classifier. Extensive experimental results demonstrate that the proposed method outperforms classical methods such as linear discriminant analysis and 3NN, when sample size is small, dimensionality is large, the data are noisy, or a combination of these.
Health, Education and Employment Outcomes in Young Refugees in the Nordic Countries: A Systematic Review
Authors: Borsch Anne Sofie , de Montgomery Christopher Jamil , Gauffin Karl , Eide Ketil , Heikkilä Elli , Smith Jervelund Signe
Published: August 2018

Objectives: Since 2000, approximately 500,000 refugees have settled in the Nordic countries, about a third of them being children and young people. To identify general trends, and to detect gaps in the existing knowledge about the socioeconomic and health status of these young refugees, this review discusses the literature regarding three key areas related to welfare policy: health, education and employment. Methods: A systematic search in PubMed, Scopus, SocINDEX, Sociological Abstracts, Embase and Cochrane, and a search for publications from relevant institutions were undertaken. All publications had to be original quantitative studies published since 1980. The total number of studies identified was 1353, 25 publications were included. Results: Young refugees had poorer mental health than ethnic minority and native-born peers. Mental health problems were related to pre-migration experiences but also to post-migration factors, such as discrimination and poor social support. Refugees performed worse in school than native-born and few progressed to higher education. Experiencing less discrimination and having better Nordic language proficiency was associated with higher educational attainment. A higher proportion of refugees were unemployed or outside the labour force compared with other immigrants and native-born. Assessment instruments varied between studies, making comparisons difficult. Conclusions: The study suggests pre-migration factors but also post-migration conditions such as perceived discrimination, social support and Nordic language proficiency as important factors for the mental health, education and employment outcomes of young refugees in the Nordic countries. Further Nordic comparative research and studies focusing on the relationship between health, education and employment outcomes are needed.
Religion, religiosity and patriarchal gender beliefs: Understanding the Australian experience
Authors: Perales Francisco , Bouma Gary
Published: August 2018

This study examines diversity in how different religious groups and people with different levels of religiosity see the value and roles of women in Australian society through an examination of their gender beliefs. This addresses a significant gap in knowledge in the Australian scholarship in religious diversity and the impact of religion in family life. Understanding the relationships between religious identity and patriarchal gender attitudes is critical to understanding certain contemporary social problems, such as the links between religion and domestic violence, and devising appropriate intervention. The analyses rely on high-quality panel data from a national sample, the Household, Income and Labour Dynamics in Australia Survey. Identifying with a religion is associated with stronger patriarchal attitudes, but there is remarkable heterogeneity in attitudes across religious groups. Higher religiosity is associated with stronger patriarchal beliefs. Differences in patriarchal beliefs between religious and non-religious people in Australia increased between 2005 and 2015.
Social capital at the tourist destination level: Determining the dimensions to assess and improve collective action in tourism
Authors: Rodriguez-Giron Santiago , Vanneste Dominique
Published: August 2018

A tourist destination, as a collective of actors trying to act together, faces the challenges of shaping a common future and self-determining its development path. This depends on its actors’ capacity to act towards collective goals. Social capital (SC) theory explains how resources are mobilised for common purposes, representing a key notion for understanding collective action. Non-tourism- and tourism-related literature on SC were analysed, finding that SC theory is used mostly as a means to study other aspects in tourism. Little has been discussed about SC itself as the object of interest. This article, therefore (1) identifies the key dimensions and levels of scope of a tourist destination’s SC, and (2) presents a structured assessment framework as the basis to reflect upon the improvement of the destination’s capacity for self-determination. The article contributes to tourist destination’s SC theory building and as the basis for further research on the subject.
Indications for and outcome in patients with the wearable cardioverter-defibrillator in a nurse-based training programme: results of the Austrian WCD Registry
Authors: Odeneg Tanja , Ebner Christian , Mörtl Deddo , Keller Hans , Dirninger Alfred , Stix Günter , Föger Bernhard , Grimm Georg , Steinwender Clemens , Gebetsberger Franz , Stühlinger Markus , Mastnak Bernadette , Haider Christian , Manninger Martin , Scherr Daniel
Published: August 2018

Background:

The wearable cardioverter-defibrillator is a treatment option for patients at temporarily high risk of sudden cardiac death or in whom implantation of a cardioverter-defibrillator is temporarily not possible.

Objectives:

The aim of this study was to provide real-world data on patients receiving this therapy in a nurse-based wearable cardioverter-defibrillator training programme.

Methods:

A registry including all patients prescribed with a wearable cardioverter-defibrillator in Austria between 2010 and 2016. Overall, 448 patients received a wearable cardioverter-defibrillator in 48 centres. Patients received structured nurse-based wearable cardioverter-defibrillator educational initial training followed by remote monitoring.

Results:

Main indications were: severe non-ischaemic cardiomyopathy (21%); recent myocardial infarction and percutaneous coronary intervention (20%); and stable coronary artery disease with percutaneous coronary intervention/coronary artery bypass grafting (14%). Eleven patients (2.5%) received 22 appropriate wearable cardioverter-defibrillator shocks. Two patients (0.4%) received three inappropriate shocks. The risk of sudden cardiac death varied between different aetiologies. Eight out of 11 (73%) patients received their first wearable cardioverter-defibrillator shock within 30 days. The main reasons for termination of the wearable cardioverter-defibrillator therapy were implantable cardioverter-defibrillator implantation (55.5%) and improvement of left ventricular ejection fraction to more than 35% (33%).

Conclusion:

The wearable cardioverter-defibrillator is an effective and safe treatment option in patients at either transiently elevated risk of ventricular tachycardia/ventricular fibrillation or mandated postponed implantable cardioverter-defibrillator implantation, with a 2.5% shock rate over a median 54 days wearable cardioverter-defibrillator treatment period. However, both the wearable cardioverter-defibrillator shock rate and implantable cardioverter-defibrillator implantation rate vary widely depending on the wearable cardioverter-defibrillator indication. Nurse-based wearable cardioverter-defibrillator training is associated with high patient adherence, with a median wearing duration per day of 23.5 (1–24) hours.
Effectiveness of Preschool-Wide Teacher-Implemented Phoneme Awareness and Letter-Sound Knowledge Instruction on Code-Based School-Entry Reading Readiness
Authors: Carson Karyn L. , Bayetto Anne E. , Roberts Anna F. B.
Published: August 2018

This study investigated the effect of preschool-wide, teacher-implemented, phoneme-focused phonological awareness (PA) and letter-sound knowledge (LSK) instruction, on raising code-based school-entry reading readiness for children with Spoken Language Difficulties (SLD) and Typical Development (TD), when supported by weekly coaching by trainee speech-language pathologists. A total of 90 4-year-old children participated, whereby 50 children, inclusive of 13 children with SLD, received 10 weeks of preschool-wide, teacher-delivered, phoneme-focused PA and LSK instruction. In all, 40 children, inclusive of 10 children with SLD, continued with the usual preschool program. Post-instruction, children in the experimental condition performed significantly higher in phoneme awareness, LSK, and early decoding compared with control children. Children with SLD in the experimental condition performed significantly higher in phoneme awareness and LSK, but not in early decoding, compared with control children with SLD. Overall, preschool-wide, teacher-implemented, phoneme-focused PA and LSK instruction can support code-based reading readiness skills for children with SLD and TD.
MicroRNA-142-3p Promotes Cellular Invasion of Colorectal Cancer Cells by Activation of RAC1
Authors: Gao Xiang , Xu Wenhuan , Lu Tingxun , Zhou Jialiang , Ge Xiaosong , Hua Dong
Published: August 2018

Background:

Colorectal cancer has been proved more difficult to treat owing to potently malignant metastasis. The present study was aimed to explore the functional role of miR-142-3p in cell migration and invasion of colorectal cancer cells, as well as its underlying mechanism.

Materials and Methods:

Expressions of miR-142-3p were analyzed in colorectal cancer tissues and cell lines. Ras-related C3 botulinum toxin substrate 1 (RAC1) was predicted as a target of miR-142-3p using software and network resources. SW480 cells were transfected with miR-142-3p expression plasmid and miR-142-3p silencer plasmid, and the expression of RAC1 and the cellular invasion were measured.

Results:

In colorectal cancer cells transfected with miR-142-3p expression plasmid, RAC1 was specifically upregulated and invasiveness of cells was downregulated. Moreover, RAC1 was significantly associated with tumor stage ( P = .029) and tumor metastasis ( P = .012).

Conclusion:

miR-142-3p promotes cellular invasion in colorectal cancer cells by activating RAC1. Thereby, miR-142-3p is a potential candidate for molecular targeted therapy of colorectal cancer.
Evaluation of a Tumor-Targeting, Near-Infrared Fluorescent Peptide for Early Detection and Endoscopic Resection of Polyps in a Rat Model of Colorectal Cancer
Authors: Jones Jade E. , Busi Susheel Bhanu , Mitchem Jonathan B. , Amos-Landgraf James M. , Lewis Michael R.
Published: August 2018

The goal of these studies was to use a tumor-targeting, near-infrared (NIR) fluorescent peptide to evaluate early detection and to guide surgical removal of polyps in a genetically engineered rat model of spontaneous colorectal cancer. This peptide, LS301, was conjugated to Cy7.5 and applied topically to the colon of adenoma-bearing Pirc rats. Ten minutes after administration, rats underwent targeted NIR laser colonoscopy. Rats were also evaluated by white light colonoscopy and narrow-band imaging, for comparison to the NIR technique. Unlike white light and narrow-band colonoscopy, NIR imaging detected unexpected flat lesions in young Pirc rats. NIR imaging was also used to assess resection margins after electrocauterization of polyps. Tumor margins remained negative at 5 weeks postsurgery, demonstrating successful polypectomy. The present studies show that NIR-targeted colonoscopy is an attractive strategy to improve screening for and resection of colorectal neoplasia.
Why Sociology Needs Science Fiction
Authors: Hirschman Daniel , Schwadel Philip , Searle Rick , Deadman Erica , Naqvi Ijlal
Published: August 2018

Using sci-fi’s metaphors, ideal types, and counterfactuals to consider our real-world problems, old and new.
When the Personal is Political—and Infectious
Authors: Reich Jennifer A.
Published: August 2018

Privilege, distrust, individual choice, and parental care all factor into vaccine resistance, but the consequences are anything but personal.
Getting Respect
Authors: Hordge-Freeman Elizabeth
Published: August 2018

Elizabeth Hordge-Freeman on Getting Respect.
When Discrimination Goes to Court
Authors: Tomaskovic-Devey Donald
Published: August 2018

Donald Tomaskovic-Devey on Rights on Trial.
Taking a Knee
Authors: Weffer Simón E. , Dominguez-Martinez Rodrigo , Jenkins Raymond
Published: August 2018

Simon E. Weffer, Rodrigo Dominguez-Martinez, and Raymond Jenkins on the timing and prevalence of NFL protests.
Tolerance Induction to Antituberculosis Drugs in a Patient With Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis Overlap
Authors: Collado-Chagoya Rodrigo , Hernández-Romero Javier , Eliosa-Alvarado Gumaro A. , Cruz-Pantoja Rubén A. , Campos-Gutiérrez Rosa I. , Velasco-Medina Andrea A. , Velázquez-Sámano Guillermo
Published: August 2018

Tolerance induction and desensitization in Stevens–Johnson syndrome (SJS) or in toxic epidermal necrolysis (TEN) have been described as an absolute contraindication by some authors, but there are cases where there is no treatment alternative. Tuberculosis (TB) remains a leading cause of morbidity and mortality in developing countries and ranks alongside HIV as a leading cause of death worldwide. Severe drug reactions, such as SJS and TEN, occurring in these individuals are lifethreatening. Since alternative therapies for TB are limited, the role of desensitization and reintroduction becomes essential. We describe a case of tolerance induction to anti-TB drugs in a patient with SJS/TEN overlap syndrome using a specifically designed premedication, comedication, and desensitization protocol.
Can Liposomal Bupivacaine Be Safely Utilized in Elective Spine Surgery?
Authors: Brown Luke , Weir Tristan , Koenig Scott , Shasti Mark , Yousaf Imran , Yousaf Omer , Tannous Oliver , Koh Eugene , Banagan Kelley , Gelb Daniel , Ludwig Steven
Published: August 2018

Study Design:

Single-blinded prospective randomized control trial.

Objectives:

To compare the incidence of adverse events (AEs) and hospital length of stay between patients who received liposomal bupivacaine (LB) versus a single saline injection, following posterior lumbar decompression and fusion surgery for degenerative spondylosis.

Methods:

From 2015 to 2016, 59 patients undergoing posterior lumbar decompression and fusion surgery were prospectively enrolled and randomized to receive either 60 mL injection of 266 mg LB or 60 mL of 0.9% sterile saline, intraoperatively. Outcome measures included the incidence of postoperative AEs and hospital length of stay.

Results:

The most common AEs in the treatment group were nausea (39.3%), emesis (18.1%), and hypotension (18.1%). Nausea (23%), constipation (19.2%), and urinary retention (15.3%) were most common in the control group. Patients who received LB had an increased risk of developing nausea (relative risk [RR] = 1.7; 95% confidence interval [CI] = 0.75-3.8), emesis (RR = 2.3; 95% CI = 0.51-10.7), and headaches (RR = 2.36; 95% CI = 0.26-21.4). Patients receiving LB had a decreased risk of developing constipation (RR = 0.78; 95% CI = 0.25-2.43), urinary retention (RR = 0.78; 95% CI = 0.21-2.85), and pruritus (RR = 0.78; 95% = 0.21-2.8) postoperatively. Relative risk values mentioned above failed to reach statistical significance. No significant difference in the hospital length of stay between both groups was found (3.9 vs 3.9 days; P = .92).

Conclusion:

Single-dose injections of LB to the surgical site prior to wound closure did not significantly increase or decrease the incidence or risk of developing AEs postoperatively. Furthermore, no significant difference was found in the hospital length of stay between both groups.
Biomechanical Analysis of Cortical Versus Pedicle Screw Fixation Stability in TLIF, PLIF, and XLIF Applications
Authors: Nomoto Edward K. , Fogel Guy R. , Rasouli Alexandre , Bundy Justin V. , Turner Alexander W.
Published: August 2018

Study Design:

Cadaveric biomechanical study.

Objectives:

Medial-to-lateral trajectory cortical screws are of clinical interest due to the ability to place them through a less disruptive, medialized exposure compared with conventional pedicle screws. In this study, cortical and pedicle screw trajectory stability was investigated in single-level transforaminal lumbar interbody fusion (TLIF), posterior lumbar interbody fusion (PLIF), and extreme lateral interbody fusion (XLIF) constructs.

Methods:

Eight lumbar spinal units were used for each interbody/screw trajectory combination. The following constructs were tested: TLIF + unilateral facetectomy (UF) + bilateral pedicle screws (BPS), TLIF + UF + bilateral cortical screws (BCS), PLIF + medial facetectomy (MF) + BPS, PLIF + bilateral facetectomy (BF) + BPS, PLIF + MF + BCS, PLIF + BF + BCS, XLIF + BPS, XLIF + BCS, and XLIF + bilateral laminotomy + BCS. Range of motion (ROM) in flexion-extension, lateral bending, and axial rotation was assessed using pure moments.

Results:

All instrumented constructs were significantly more rigid than intact ( P < .05) in all test directions except TLIF + UF + BCS, PLIF + MF + BCS, and PLIF + BF + BCS in axial rotation. In general, XLIF and PLIF + MF constructs were more rigid (lowest ROM) than TLIF + UF and PLIF + BF constructs. In the presence of substantial iatrogenic destabilization (TLIF + UF and PLIF + BF), cortical screw constructs tended to be less rigid (higher ROM) than the same pedicle screw constructs in lateral bending and axial rotation; however, no statistically significant differences were found when comparing pedicle and cortical fixation for the same interbody procedures.

Conclusions:

Both cortical and pedicle trajectory screw fixation provided stability to the 1-level interbody constructs. Constructs with the least iatrogenic destabilization were most rigid. The more destabilized constructs showed less lateral bending and axial rotation rigidity with cortical screws compared with pedicle screws. Further investigation is warranted to understand the clinical implications of differences between constructs.
Fit and Feasibility: Adapting a Standardized Curriculum to Prepare Future Health Professionals to Address Alcohol Misuse
Authors: King Diane K. , Neander Lucía L. , Edwards Alexandra E. , Barnett Jodi D. , Zold Amanda L. , Hanson Bridget L.
Published: August 2018

Standardized screening, brief intervention, and referral to treatment (SBIRT) is effective when used by health care professionals to assess, educate, and intervene to address risky alcohol use. To accelerate SBIRT training within academic settings, the Substance Abuse and Mental Health Services Administration funded implementation of its SBIRT curriculum to promote its use by future health care professionals. We report on how SBIRT content was implemented within nursing, social work, psychology, and family medicine residency programs at a state university. The reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) evaluation framework was used to compare delivery of SBIRT curriculum across health professions. Survey data measured changes in student knowledge, confidence, and responsibility to use SBIRT for alcohol and drugs, pre- and post-SBIRT training. Twelve months postgraduation follow-up surveys examined maintenance of outcomes and SBIRT use in practice. Observational data explored fidelity and adaptations made to curriculum content and delivery logistics. Results indicated that instructor adoption, fidelity, and format varied across health professional training programs, with adaptations made to improve fit, role alignment, and cultural relevance. Despite variation in curriculum delivery, students demonstrated significant gains in knowledge and confidence, ( p < .001). Key implementation and maintenance challenges included time constraints, instructor buy-in, competing accreditation requirements, and costs for using the university simulation laboratory to practice SBIRT. Strengths supporting maintenance included flexibility to adapt curriculum, department champions, and electronic resources to support curriculum delivery. Results suggest that adaptations maximizing the feasibility and fit of SBIRT within existing courses enhanced its adoption and maintenance potential without sacrificing effectiveness.
Confronting Biological Reductionism From a Social Justice Agenda: Transformative Agency and Activist Stance
Authors: Stetsenko Anna
Published: August 2018

This article draws attention to contemporary research and theorizing that counters and resolutely dispels biological determinism laden with a plethora of mythic racial, gender, dis/ability and other types of unproven assumptions, conjectures, and biases. Based on a wide range of emerging conceptual breakthroughs and a growing body of evidence across neurosciences, epigenetics, developmental systems perspectives, and activity-centered cultural–historical frameworks, the argument can be made that all persons have infinite potential—incalculable in advance, unlimited, and not predefined in terms of any putatively inborn “endowments.” From this perspective, educational success is correlative with access to social resources and mediators such as teacher experience and skills. These and other radical implications can be drawn out with more force if this emerging body of anti-reductionist and anti-biodeterminist knowledge is connected to and integrates critical and sociocultural scholarship with agendas of social justice and equality such as exemplified in works by Marx and Vygotsky. At the same time, critical and sociocultural scholarship can draw on this emerging body of knowledge to support its struggles for a better society and education. For these two broad strands of scholarship to connect and benefit from each other, a revision of the role of subjectivity and activism in research is required, with steps in this direction discussed in this article.
Evaluation of Umbilical Artery Doppler Indices in Pregnant Women With Sickle Cell Anemia Disease at a Nigerian Tertiary Hospital
Authors: Agbaje Olubusayo Abimbola , Adeyomoye Adekunle Ayokunle Olakunle , Omidiji Olubukola Abeni Titilayo , Oboke Ozoemena S. , Afolabi Bosede Bukola
Published: August 2018

Pregnant patients with sickle cell anemia (HbSS) are at risk of adverse outcomes to the mother and the fetus due to unique pathophysiologic changes. The purpose of this study was to determine the umbilical artery (UA) Doppler indices at 26 weeks gestational age (GA) in HbSS women with uncomplicated pregnancies and compare with the obstetric outcome. In this cohort study, 60 HbSS and 60 normal hemoglobin (HbAA) women with uncomplicated pregnancies were recruited from the antenatal clinic and prospectively followed to delivery. UA velocimetry, fetal biometry, maternal hematocrit, and parity were assessed at 26 weeks. Fetomaternal outcomes were also documented. UA Doppler indices and estimated fetal weights were comparable to those of HbAA control subjects at 26 weeks GA. There was a statistically significant increase in adverse obstetric outcomes in HbSS patients. There was no correlation between maternal hematocrit and artery indices. Further research is required to determine cutoff values and optimal timing for sonography in HbSS patients.
Sonographic Features of Estrogen-Negative Breast Cancers: A Correlation Study With Human Epidermal Growth Factor Type II Overexpression
Authors: Gity Masoumeh , Borhani Ali , Mokri Mehrdad , Shakiba Majid , Atri Morteza , Batavani Nasim
Published: August 2018

The purpose of this study was to retrospectively review sonographic imaging features of estrogen-negative breast cancers and compare tumors with and without human epidermal growth factor type II (HER2) overexpression. Breast sonography findings from a sample of 54 patients with estrogen-negative breast cancer as well as pathological data and HER2 status were reviewed. Sonographic features including size, depth shapes, margin, location, patterns of internal echoes, posterior echoes, orientation, and presence of halo and clinicopathologic data and imaging features were correlated with tumor HER2 status. Based on these 54 patients with estrogen-negative breast cancers, 21 patients were positive for HER2 receptor, and 33 patients were negative for HER2 receptor. Among HER2 positive cancers, irregular shape, microlobulation, indistinct margins, posterior shadowing, a thin halo, heterogeneous internal echoes, and parallel orientation were the most frequent sonographic features. No associations were found between HER-2 status and tumor size, shape, margins, posterior feature, halo, internal echoes, or orientation on sonography.
Cooperative PSGL-1 and CXCR2 signaling in neutrophils promotes deep vein thrombosis in mice
Authors: Yago Tadayuki , Liu Zhenghui , Ahamed Jasimuddin , McEver Rodger P.
Published: August 2018

Publisher's Note: There is a Blood Commentary on this article in this issue.
Neural networks
Authors: Ganssle Graham
Published: August 2018

We've all heard a proselytizing hyperbolist make the artificial-intelligence-is-going-to-steal-my-job speech. If you subscribe, look at the code in the notebook accompanying this tutorial at https://github.com/seg/tutorials-2018 . It demonstrates a small neural network. You'll find a simple system composed chiefly of multiply and add operations. That's really all that happens inside a neural network. Multiply and add. There's no magic here.
Adequacy of Pathologic Reports of Invasive Breast Cancer From Mastectomy Specimens at Tikur Anbessa Specialized Hospital Oncology Center in Ethiopia
Authors: Yesufe Abdu A. , Assefa Mathewos , Bekele Abebe , Ergete Wondwossen , Aynalem Abreha , Wondemagegnehu Tigeneh , Tausjø Johan , Assefa Tessema Gizachew , Kantelhardt Eva Johanna , Gansler Ted , Jemal Ahmedin
Published: August 2018

Purpose

Although information from pathology reports is essential to the care of individuals with cancer and to population-level cancer control, no systematic evidence exists regarding the adequacy of breast pathology reporting in Ethiopia. This study audited pathology reports of mastectomy specimens from patients evaluated at the Tikur Anbessa Specialized Hospital Oncology Center in Addis Ababa, Ethiopia.

Methods

Mastectomy pathology reports from February 2014 through January 2016 were assessed for gross and microscopic information considered by the Breast Cancer Initiative 2.5 (BCI 2.5; formerly the Breast Health Global Initiative) guideline to be necessary for care of patients with breast cancer stratified according to basic, limited, and enhanced resource settings.

Results

Fewer than two thirds (61.6%) of the 417 reports we reviewed included all four of the BCI 2.5 basic pathology data elements we could evaluate with available data (tumor category, lymph node category, histologic type, and histologic grade). Only 1.0% of reports included all three pathology data elements recommended for limited resource settings (estrogen receptor status, margin status, and lymphovascular invasion). Several elements were significantly more likely to be noted in reports from nonpublic hospitals than from public hospitals. Although only three of 417 reports included checklists or templates, all three of these reports included all of the basic pathology information, and they all included at least two of the three limited pathology elements not already on the basic list.

Conclusion

More than one third (38.4%) of mastectomy pathology reports did not meet BCI 2.5 standards for basic resource settings. Quality measurement and improvement programs and capacity-building interventions by national pathology and oncology organizations, collaboration with medical and public health organizations in neighboring countries, adoption of synoptic reporting templates, use of electronic pathology reporting, and histotechnology and histopathology training collaborations with laboratories in high-resource regions are recommended.
Stability and Effect of Hydration on Calcium Oxide Cluster Ions, CanOm+, in the Gas Phase
Authors: Masuzaki Daigo , Takehashi Yuma , Mafuné Fumitaka
Published: August 2018

Thermal stability and effect of hydration were studied for calcium oxide cluster ions, CanOm+, using gas-phase thermal desorption spectrometry. Near stoichiometric CanOn+, CanOn+1+, and CanOn+2+ clusters were formed in the gas phase at 300 K, and the more oxygen-rich clusters, CanOn+2+ (n = 3, 5, 7, 9), released O2 to form CanOn+, when heated to a higher temperature. The stability and the propensity of O2 release were well explained in terms of the formal oxidation states of the atoms in the clusters. Reaction of CanOn+ and CanOn+1+ (n = 4, 6, 9) with a water molecule forms CanOn+1H2+ and CanOn+2H2+, respectively. Density functional theory (DFT) calculations on the stable geometries of Ca4O5H2+ and Ca4O6H2+ suggested that an O–H bond of H2O was activated upon reaction and di-hydroxides, Ca4O3(OH)2+ and Ca4O4(OH)2+, were formed via exothermic processes. Upon heating, OH and O2H were released from Ca4O3(OH)2+ and Ca4O4(OH)2+, respectively, to form Ca4O3(OH)+. For other clusters (n = 3, 5, 7 and 8), OH release and O2H release were not observed by the simple heating of CanOn−1(OH)2+ and CanOn(OH)2+. Nevertheless, solvation of gas phase CanOm+ by multiple water molecules was found to generate hydrated CanOn−1(OH)+.
Isenção de impostos - Incompetência da legislatura federal para conceder
isenções de impostos estaduais e municipais, e recíprocamente
Authors: Carneiro Manuel
Published: August 2018

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Imposto territorial urbano - Isenção
Authors: Nunes Castro
Published: August 2018

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Prescrição das dívidas fiscais - A prescrição bienal estabelecida no
código civil e as dívidas fiscais de valor inferior a cem cruzeiros
Authors: Oliveira Goulart De
Published: August 2018

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Executivo fiscal
Authors: Martins Homero
Published: August 2018

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Pensão especial
Authors: Filho A. Alvim
Published: August 2018

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Alimentos - Desconto em folha de servidor inativo
Authors: Oliveira João Domingues de
Published: August 2018

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Conselhos administrativos - Incompatibilidade funcional de seus
membros
Authors: Silva Carlos Medeiros
Published: August 2018

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Registro de comércio - Competência
Authors: F. A. M.
Published: August 2018

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Fornecimento de gás - Fraude do usuário
Authors: Lima J. Mendonça
Published: August 2018

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Ato administrativo - Revogabilidade
Authors: Oliveira A. Gonçalves de
Published: August 2018

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Bibliografia
Authors: Leal Victor Nunes
Published: August 2018

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Dos contratos administrativos
Authors: Silva Jose Saldanha da Gama e
Published: August 2018

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O regime jurídico das terras da Fazenda Nacional de Santa Cruz
Authors: Silva Luciano Pereira da
Published: August 2018

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Dos funcionários das autarquias
Authors: Cavalcanti Themístocles Brandão
Published: August 2018

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O fato gerador do imposto
Authors: Jeze Gaston Paul Amedee
Published: August 2018

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Atos administrativos
Authors: Leal Vítor Nunes
Published: August 2018

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Serviço Público
Authors: Carneiro Alaim de Almeida
Published: August 2018

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Imposto de transmissão causa-mortis de bens incorpóreos
Authors: Pereira Santos
Published: August 2018

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Taxa de calçamento - Constitucionalidade
Authors: Wiedemann Ney Da Silva
Published: August 2018

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Aposentadoria
Authors: Mello Leopoldo Cunha
Published: August 2018

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Exposição de motivos e considerandos de atos legislativos
Authors: Silva Carlos Medeiros
Published: August 2018

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Terras Públicas
Authors: Vargas Getulio
Published: August 2018

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Funeral
Authors: Barbosa Henrique
Published: August 2018

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Restituiçãode fundo agrícola
Authors: Tacito Caio
Published: August 2018

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Imposto sobre transmissão de bens incorpóreos
Authors: Guimarães Hahnemann
Published: August 2018

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Responsabilidade civil do estado. Danos causados por atos da
multidão
Authors: Gallotti Luis Otavio
Published: August 2018

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Código florestal e sua execução
Authors: Silva Luciano Pereira da
Published: August 2018

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Estatuto dos funcionários públicos civis da união e a legislação
posterior
Authors: Carneiro Alaim de Almeida
Published: August 2018

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Decreto-lei n.°7.502, de 30 de abril de 1945
Authors: Vargas Getulio
Published: August 2018

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Decreto-lei n.°7.373, de 13 de março de 1945
Authors: Vargas Getulio
Published: August 2018

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Decreto-lei n.°7.440, de 5 de abril de 1945
Authors: Vargas Getulio
Published: August 2018

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Decreto-lei n.°7.474, de 18 de abril de 1945
Authors: Vargas Getulio
Published: August 2018

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Contribuição a teoria do processo administrativo
Authors: Menegale José Guimarães
Published: August 2018

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Banco do Brasil. Isenção de impostos e taxas
Authors: Benício J.
Published: August 2018

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Funcionário público. Estabilidade. Contagem de tempo de serviço
Authors: Melo J.A. de Carvalho e
Published: August 2018

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Funcionário municipal. Estabilidade
Authors: Costa A. C. Pereira da
Published: August 2018

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Funcionário público. Estabilidade. Demissão
Authors: Gonzaga J. M.
Published: August 2018

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Pensão de montepio militar e meio-soldo
Authors: Filho A. Alvim
Published: August 2018

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Imposto sobre renda. Cônjuges estrangeiros
Authors: Fazenda Ministério Da
Published: August 2018

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Montepio civil dos funcionários públicos
Authors: Oliveira João Domingues de
Published: August 2018

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Direito disciplinar
Authors: Bittencourt Carlos Alberto Lúcio
Published: August 2018

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Vencimentos de desembargador
Authors: Magalhães Agamemnon
Published: August 2018

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Autarquias. Controle
Authors: Filho Alexandre Marcondes
Published: August 2018

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Funcionário interino. Ocupação de cargo em substituição do
titular
Authors: Ludovico Dr.
Published: August 2018

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Abono familiar. Guarda de menores
Authors: Saraiva Oscar
Published: August 2018

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Relações jurídica entre o Estado e os seus servidores
Authors: Melo Osvaldo Aranha Bandeira de
Published: August 2018

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Decreto-lei n.°7.675 de 26 de junho de 1945
Authors: Silva Carlos Medeiros
Published: August 2018

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Decreto-lei n.°7.527 de 7 de maio de 1945
Authors: Vargas Getulio
Published: August 2018

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Decreto-lei n.°7.887 de 21 de agosto de 1945
Authors: Vargas Getulio
Published: August 2018

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Contribution to the structural study of the Rhodiani ophiolites, Vourinos massif
Authors: PHOTIADES A. , ΡΟΜΟΝΙ-ΡΑΡΑΙΟΑΝΝΟΥ F.
Published: August 2018

The Rhodiani area geologically is comprised of a sequence of Mesozoic and Tertiary thrust sheets, including the Jurassic ophiolite and sedimentary covers; they composed of an ultramafic unit overlain by an Albian to Cenomanian redeposited limestone cover, and at the top a volcanic unit that is overlain by neritic to pelagic Upper Jurassic to Upper Cretaceous age limestone and Upper Maastrichtian flysch deposits. These thrust sheets were emplaced over the Pelagonian platform. Therefore the Rhodiani "ophiolite" is not a single thrust unit, but it is an imbricated ophiolite tectonic structure resulting from a two-stage emplacement process; the ultramafic unit was overthrust on the melange of the Pelagonian platform during the initial emplacement (Jurassic) and the volcanic unit was re-thrust on the former during subsequent post-Eocene tectonic phase
Pleistocene faunas of "Glyfada" cave, Diros, Laconia
Authors: ΣΥΜΕΩΝΙΔΗΣ Ν. Κ. , ΓΙΑΝΝΟΠΟΥΛΟΣ Β. Ι.
Published: August 2018

The cave of "Glyfada" is located in Mani peninsula, in the perfecture of Laconia, about 2 km. north to the Municipality of Diros. It was discovered in 1923 by the local agents of the town, but it has been systematically studied since 1949 up to now; a corridor-with the secondary developments-of 10.606 m. length has been surveyed and mapped, while it was found that there is a part of 1833 m. being submarine. The cave has been developed in semi-crystallized Upper Cretacean and Eocean limestones of Mani Unit; it develops a labyrinth like morphology. The first paleontological findings are reported in 1957-58,by Petrochilos, the first geologist who discovered the cave. Since 1994, there has been ongoing a systematic study of the environment of the cave, while, in thirteen different sites in the cave, a large amount of bones was located, attributed to prehistoric mammals and specifically to Hippopotammus amphibius LINNE, although the new evidence provides data for a new species. It was also located the species Martes foina ERXLEBEN, Dama dama LINNE, a fragment of the upper jaw RUMINANDIA, bones of birds, the carnivore Panthera sp., Panthera leo LINNE, Crocuta crocuta ERXLEBEN and, lastly, Monachus monachus. The taxonomic identification was conducted in the Paleontological Laboratory of the University of Athens and the Institute of Paleontology in Vienna. The dating was undertaken in the Centre of Isotopie Research in the University of Groningen in Holland.
New findings of fossil large mammal remains in the Penios valley (Area of Larissa, Thessaly, Greece)
Authors: ATHANASSIOU A.
Published: August 2018

Fossil large mammal remains that come from the Penios valley, Thessaly, are described and compared to already known specimens. The studied material includes two elephant mandibles, tusk fragments and limb bones, as well as a part of a large bovid skull. On the basis of morphology and biometry the sample is taxonomically referred to the species Elephas antiquus and Bos primigenius. An Upper Pleistocene age is assumed.
Otoliths from the lower Pliocene of the section Prassies (Rethymnon, ΝW - Crete). Systematics - Paleoecology
Authors: ΜΑΡΚΟΠΟΥΛΟΥ- ΔΙΑΚΑΝΤΩΝΗ Α. , ΚΑΓΚΙΟΥΖΗΣ Γρ.
Published: August 2018

This paper concerns the study of Otoliths coming from the sediments of the L. Pliocene of the region Kefales of the community Prassies at the northern part of Rethymnon (NW- Central Crete), 10 km from it and the places of sampling are along the road Rethymnon- Amari to the village Prassies. These sediments are yellowish with a visible inclination and sedimentary structures overlying in unconformity on the alpic substrate. The sediments of the studied area consist of Miocene, Plio-Pleistocene and Holocene formations. Holocene appears with littoral deposits (sand, gravels and alluvian deposits) 20 m. The Plio - Pleistocene formations –marine deposits- consisting of brawn marls without fossils (upper members), of marls with macrofossils (intermediate members) and white marls and clays with Algae and Pectinidae, Ostreidae, some Gastropods and Echinoids (lower members). Total height 150 m. The Miocene has a total thickness of 200 m. The studied Otoliths belong to the orders: 1. Iniomi (Myctophiformes): Diaphus splendidus (PROCHAZKA 1893), Diaphus sp., Diaphus holti TANING, 1918, Diaphus kokeni (PROCHAZKA 1893), Ceratoskopelus madarensis (LOWE 1839), Myctophidarum edwardsi (SAUVAGE 1873), 2. Anacanthini (Gadiformes): Bregmaceros albyi (SAUVAGE 1880), Macrurus novus BASSOLI, 3. Percomorphi (Perciformes): Gobius vicinalis KOKEN., Gobius sp. The studied Otoliths, mentioned for the first time in Greece, give important results on the biogeography and paleogeography and contribute to our knowledge about this fossilized group.
New paleontological and stratigraphical data on the upper - cretaceous transgression of the Pelagonian zone s.l. (Marmeiko, Ptoon Mt. NE Beotia)
Authors: ΜΕΡΜΙΓΚΗ Α. , ΜΑΡΚΟΠΟΥΛΟΥ - ΔΙΑΚΑΝΤΩΝΗ Α. , ΖΑΜΠΕΤΑΚΗ - ΛΕΚΚΑ Α.
Published: August 2018

This paper concerns the study of a transgressive series, which overlies the upperjurassic oolitic limestones of subpelagonian zone, as well as the lateritic deposits, resulting from the alteration of the ophiolitic and fill the karstic cavities of the above mentioned limestones in NE Beotia (Fig.l). The purpose of this study is to• elucidate the age of the transgression, that occurred on the Jurassic limestones of the pelagonian platform at this region.• Discuss about the observed diachronism of the Late Cretaceous transgression on the Pelagonian platform.It is based on the study of micro- and macrofauna occurred in a section we describe in the "Marmeiko" area, on the Ptoon mountain. NOETH (1931) was the first who defined as Upper Turonian the age of the transgressive series, based on the study of Rudists. Later, BIGNOT & GUERNET (1968) studied the microfauna and attributed an age of lower Senonian. STEUBER (1993) based on the study of Hippuritidae, defined as Turonian and later (1995) as Turonian - Coniacian the age of the transgessive series. The basal part of the series consists of marls and marly limestones alternations. An abundant micro and macrofauna is found in this part of the section, as well as the first Rudist biostrome. In the middle part of the section 2 Rudist biostroms alternate with bioclastic limestones, containing abundant microfauna. In the upper part marls alternate with cherty limestones. The determinated micro- and macrofauna (Fig. 1), precises the age of the transgressive series as Santonian. This result confirms the diachronism of the transgressive phenomenon on the Pelagonian Upper- Jurassic limestones and the overthrusted ophiolites (AUBOUIN et al. 1960, BRUNN et al. 1972, KALLERGIS & ALBANTAKIS 1970, MAVRIDIS et al. 1979, NOETH 1931, BIGNOT & GUERNET 1968, CLEMENT & FERRIERE 1973, BIGNOT et al. 1973, STEUBER 1993, 1995, SKARPELIS & ZAMBETAKIS – LEKKAS 1998)
The presence of marin Pliocene sendiments in the Mesohellenic Trough (Pramoritsa banks, Grevena, Greece)
Authors: ΦΟΥΝΤΟΥΛΗΣ Ι. , ΜΑΡΚΟΠΟΥΛΟΥ-ΔΙΑΚΑΝΤΩΝΗ Α. , ΜΠΑΚΟΠΟΥΛΟΥ Α. , ΜΩΡΑΪΤΗ Ε. , ΜΙΡΚΟΥ Μ. Ρ. , ΣΑΡΟΓΛΟΥ Χ.
Published: August 2018

Detailed lithostratigraphic study of the postalpine deposits that build Pramoritsa river banks - tributary of Aliakmonas river- north of Grevena (Greece), showed that the marine molassic deposition did not cease in the Upper Miocene but continued in the Lower Pliocene, too. Systematic sampling revealed abundant pelagic and benthic fossils, the presence of which {Bulimina exilis, Bulimina costata, Neogloboquadrina acostaensis, Globigerinella pseudobesa, Globoquadrina venezuelana, Neoeponides schreibersii, Pulleniatina obliquiloculata, Dorothia gibbosa) proves that marine facies went on, at least, until the Lower Pliocene and that the depositional environment was characterized as coastal with warm waters. According to the Nannoplankton flora correlated with standard nannoplankton -zones-subzones NNllb Amaurolithus delicatus, Discoaster quinqueramus) and NN13 (Ceratolithus rugosus) of MARTINI, 1971 and OKADA & BUKRY, 1980 during the Late Miocene -Early Pliocene. Besides, some characteristics of the Pliocene sediments are described, based on macro- and microscopic observations.
Messinian biostratigraphy based on foraminifera and ostracodes in Ionian zone of Albania
Authors: BULI K. , PRILLO S. , BULl Ν. , KUMATI L. , ROQl R.
Published: August 2018

Messinian biostratigraphy based on foraminifera and Ostracodes was studied in several surface sections within Peqin-Durres region. The sections are located in the eastern and northwestern part of the Peri-Adriatic Foredeep (PAF) of Albania (FigJ ). The Thartor section is located more or less in the center of the region studied. Its Messinian sediments in particular late Messinian one are well exposed and just in this place they represent the boundary of great differences between these sediments and those that could be occurred towards east or towards south. Firstly, here well distinguished the preevaporitic sequence which very rapidly wedge-out towards southeast. Secondly, here is the latest southeast boundary of gypsum blocks occurrence. Moreover in this section the lack of "lago-mare" biofacies is apparently owing to its erosion. Towards northern and western sections the lower boundary of "lago-mare" biofacies is well determined lithologically and faunistically. Towards southeast and eastern sections this boundary determined also by first occurrence of Cyprideis, Candona etc., as above but it seems to be not synchronous from section to section. In this aspect this "lago-mare" biofacies is more similar with a Paratethyan biofacies. Within the gypsum bearing region "lago-mare" biofacies is focused in the latest Messinian only, in this aspect it could be called "Tethyan lago-mare' biofacies.
Palaeoenvironmental significance of a late Miocene benthic foraminifera fauna from Apostoli Formation, Central West Crete, Greece
Authors: DRINIA H.
Published: August 2018

The palaeoenvironmental and palaeoecological reconstruction of the Apostoli Basin (Crete, Rethymnon Region) during early Late Miocene by means of benthic foraminifers is given. Biologically important factors, such as oxygen and nutrient content of sea-water, played a great role in the evolution of the palaeoecosystem. A gradual deepening took place during the deposition of the Apostoli Formation. The sediments of the lower part of the formation document a shallow-marine environment with vegetation in the neighborhood. In the middle part of the formation sediments are characterized by intermediate oxygenated conditions, whereas the upper part of it is characterized by the establishment of a restricted envrironment, where organic matter accumulates and infaunal opportunistic species capable of surviving in stressed conditions dominate, being favoured by abundant nutrients.