bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating the acceptability of an online patient decision aid for the surgical management of lower urinary tract symptoms secondary to benign prostatic hyperplasia
Authors: Bouhadana David , Nguyen David-Dan , Raizenne Brendan , Schwarcz Joe , Gordon Harvey , Chughtai Bilal , Elterman Dean S. , Lavallée Luke T. , Martin Paul , McAlpine Kristen , Paterson Ryan , Razvi Hassan , Zorn Kevin C. , Bhojani Naeem
Published: August 2021

Introduction: The growing number of surgical options available to treat benign prostatic hyperplasia (BPH), may overwhelm patients and urologists when deciding on an optimal treatment. Therefore, we developed an online patient decision aid (PtDA) that includes all guideline-approved surgical modalities. The objective of this study was to assess the acceptability of the PtDA among former BPH surgery patients and urologists that treat BPH surgically.

Methods: The International Patient Decision Aids Standards were used to develop a PtDA that includes monopolar transurethral resection of the prostate (TURP), bipolar TURP, GreenLight photovaporization, endoscopic enucleation of the prostate, Rezum, Urolift, Aquablation, open retropubic prostatectomy, and robotic simple prostatectomy as management options. Eleven urologists that regularly treat BPH and 19 patients who received BPH surgery were recruited. Alpha-testing was performed using a validated acceptability scoring system.

Results: For all sections of the PtDA, most urologists agreed that the language used was easy to follow (91.9%), that the amount of information provided was adequate (63.6%), that the length of the PtDA was appropriate (63.6%), and that the outcomes reported were correct (81.8%). All 19 patient participants agreed that the language used was easy to follow, and most found that the amount of information provided was adequate (84.2%), that the length of the PtDA was appropriate (84.2%), and that the outcomes reported were well-explained (89.5%).

Conclusions: Our PtDA was found to be acceptable among urologists and patients. These results demonstrate that most of the participants either recommend the use of this tool or plan to incorporate it in their clinical practice.
ALMOST CONVERGENCE AND ALMOST SUMMABILITY
Authors: SAVAS EKREM
Published: August 2021

The purpose of this paper is to introduce and discuss the spaces of almost summable sequences. Also some matrix transformations have been charac- terized.
ON AXIOMATIC CHARACTERISATION OF GENERALIZED QUALITATIVE MEASURE OF VARIATION OF INFORMATION THROUGH GENERATING FUNCTION
Authors: Singh R. P. , Bhardwaj J. D.
Published: August 2021

The aim of the present contribution is to define a generalized qual- itative measure of variation of information through generating function and to characterize it axiomatically. In this sequence the generaliz.ed qualitative measure of information improvexnent as the difference of generalized measure of information of variation defined earlier is also defined. Most of the measures studied so far thus turns out to be particular ones. Some basic applicative properties are discussed.
A NOTE ON LATTICE OPERATIONS OF RIESZ SPACES OF ORDER BOUNDED OPERATORS
Authors: LAVRIČ BORIS
Published: August 2021

Let $L$, $M$ be Archimedean Riesz spaces with $M$ Dedekind complete, and let $\mathcal L_b(L,M )$ be the Riesz space of order bounded linear operators from $L$ into $M$. A theorem of Abramovic [1] on lattice operations of $\mathcal L_b(L,M )$ is generalized on Riesz spaces $L$ in which a weak form of Freudenthal's spectral theorem [4] holds.
Zabytkowy szpital – problematyczna koegzystencja podmiotu z przedmiotem ochrony konserwatorskiej
Authors: Dankiewicz Katarzyna
Published: August 2021

Celem artykułu jest zwrócenie uwagi na brak wsparcia instytucjonalnego dla rozwoju rodzimych cenionych historycznych placówek ochrony zdrowia na tle odmiennej sytuacji wiodących szpitali zagranicznych. Autorka dostrzega w aktualnych miejskich i regionalnych planach rozwoju województwa mazowieckiego słabo zarysowane działania w kierunku rewitalizacji szpitalnego dziedzictwa. Metodologia pracy opiera się na kwerendach dostępnych zasobów online oraz in situ Mazowieckiego Konserwatora Zabytków, UE, Strategii Rozwoju Mazowsza 2030, a także na badaniach własnych wybranych historycznych szpitali.
Rewitalizacja posadzek betonowych typu lastrico w obiektach zabytkowych. Część 1
Authors: Świątek-Żołyńska Sylwia , Niedostakiewicz Maciej , Ryżyński Władysław
Published: August 2021

artykule przedstawiono zagadnienia materiałowe i technologiczne dotyczące posadzek typu lastrico w aspekcie oceny ich stanu technicznego oraz sposobów naprawy i rewitalizacji. Określone zostały ramowe wytyczne prowadzenia oceny stanu technicznego, etapowania prac renowacyjnych, jak również sposobów wzmocnienia oraz wykonywania uzupełnień w warstwie wierzchniej posadzki lastrico. Szczególną uwagę zwrócono na efekty wizualne i estetyczne rewitalizacji posadzek lastrico w obiektach zabytkowych.
Euglycemic Diabetic Ketoacidosis in Type 1 Diabetes on Insulin Pump, with Acute Appendicitis: A Case Report
Authors: Thompson Brian , Kitchen Anthony
Published: August 2021

Introduction: Recently, euglycemic diabetic ketoacidosis has been an increasing topic of discussion within emergency medicine literature. Euglycemic diabetic ketoacidosis can easily be missed, as a normal point-of-care glucose often mistakenly precludes the work-up of diabetic ketoacidosis.
Case Report: A 16-year-old female with a past medical history of type 1 diabetes presented to the emergency department with altered mental status, vomiting, and abdominal pain. She was diagnosed with euglycemic diabetic ketoacidosis.
Conclusion: Reported cases of euglycemic diabetic ketoacidosis are most frequently attributed to sodium glucose cotransporter-2 inhibitors, but other potential causes have been discussed in the literature. In this patient, a starvation state with continued insulin use in the setting of acute appendicitis led to her condition.
Erector Spinae Plane Block in the Emergency Department for Upper Extremity: A Case Report
Authors: Lee Daniel , Martel Marc , Reardon Robert
Published: August 2021

Introduction: The erector spinae plane block (ESPB) has been described as an effective analgesic modality in the emergency department (ED) for thoracic pain. It has not previously been described to treat ED patients with pain in the upper extremity.

Case Report: We present a case of a 52-year-old female who presented to the ED with an acute exacerbation of her chronic radicular left arm pain originating after a fall she sustained one year prior. After a variety of analgesic modalities failed to control her pain, an ESPB was used to successfully treat her pain and facilitate discharge from the ED.

Conclusion: A significant portion of patients who present to the ED have underlying chronic pain; however, opioids are a potentially dangerous and ineffective modality to treat chronic pain. In addition to avoiding opiates, the ESPB has the advantage of preserving motor function, thus avoiding the complications associated with brachial plexus blockade.
Case Report: Diagnosis of Late Spontaneous Intraocular Lens Dislocation on Point-of-care Ultrasound
Authors: Pizarro Alexandra , Kehrl Thompson
Published: August 2021

Introduction: Spontaneous intraocular lens (IOL) dislocation is a rare, but serious, complication following cataract surgery.
Case Report: We report a case of patient with a remote history of cataract surgery presenting to the emergency department with monocular blurred vision. Ocular point-of-care ultrasound (POCUS) facilitated diagnosis of a late spontaneous IOL dislocation.
Discussion: Prosthetic IOL dislocations are being reported with increasing frequency. Prompt recognition of IOL dislocation is essential to prevent secondary complications, including acute angle-closure glaucoma and retinal detachment, which can result in permanent vision loss.
Conclusion: Point-of-care ultrasound is a rapid, noninvasive imaging modality for early detection of IOL dislocation to help guide management, improve patient outcomes, and mitigate long-term sequelae.
Staghorn Calculus: A Stone out of Proportion to Pain
Authors: Malone John , Gebner Riley , Weyand Jonathan
Published: August 2021

Case Presentation: A 25-year-old woman presented to the emergency department with two weeks of crampy right-flank pain, and urinary urgency and frequency. She was found to have a staghorn calculus filling her entire right renal pelvis on computed tomography imaging.
Discussion: In contrast to ureteral calculi, staghorn calculi are more commonly observed in female patients and typically present with an indolent clinical course. A low threshold for imaging should be maintained, as prompt referral to urology for stone removal or treatment is necessary. Staghorn calculi have a high likelihood of leading to renal failure or urosepsis without treatment.
Stroke or No Stroke: A Case Report of Bilingual Aphasia
Authors: Gray Matthew , Ernst Jacob , Ashworth Simeon , Patel Ronak , Couperus Kyle
Published: August 2021

Introduction: Bilingual aphasia is an atypical stroke presentation in the multilingual patient where an isolated aphasia occurs in one language while the other remains unaffected.

Case Report: A multilingual male presented to the emergency department with expressive aphasia to English but who was still able to speak fluently in French. Receptive English was preserved. While his National Institute of Health Stroke Scale score was technically zero, his pure aphasia component qualified him as an exception. He regained some repetitive English, so fibrinolyitic therapy was not initiated.

Conclusion: Bilingual aphasia is an indication for fibrinolysis given the impact that a pure aphasic stroke has on quality of life.
Anterior Lung Evisceration Following an Assault with Knife: A Case Report
Authors: Ferreira-Pozzi Martín , Erramouspe Pablo , Folonier Juan , Perez Mauro , González Daniel , Laurin Erik
Published: August 2021

Introduction: Evisceration of the lung is a rare consequence of open chest trauma that can be fatal. Evisceration of the lung refers to the protrusion of lung parenchyma through a defect of the thoracic wall, without parietal pleural or skin coverage.
Case report: A 20-year-old man was brought to the emergency department (ED) with left lung evisceration from stab wounds. The eviscerated lung was left in place, and the patient was not intubated in the ED. He was immediately taken to the operating room (OR) for intubation and surgical repair. Other significant injuries were ruled out, the eviscerated lung was retrieved, the chest wall defect was closed, and the patient recovered well. He was discharged after seven days in good condition.
Conclusion: The initial management of patients with lung evisceration is critical to prevent rapid decompensation and death. Appropriate ED airway management, lung retrieval in the OR, and thoracic wall repair is recommended for patients with lung evisceration.
Uveal Melanoma Identified as Ocular Mass on Point-of-care Ultrasound
Authors: Spungen Hannah , Weingrow Daniel
Published: August 2021

Case Presentation: A 41-year-old man presented to the emergency department with five months of progressive monocular vision loss in his right eye, which he described as a gradually descending and enlarging black spot. He had no light perception in his right eye with elevated intraocular pressure and an afferent pupillary defect, while his left eye visual acuity and pupillary exam was normal. Point-of-care ultrasound demonstrated a hyperechoic, pedunculated mass in the posterior chamber of his right eye, consistent with a diagnosis of ocular melanoma. Ophthalmology scheduled the patient for an elective, right eye enucleation the following week, after which a diagnosis of uveal melanoma (UM) was confirmed on histopathology.

Discussion: Uveal melanoma is an uncommon diagnosis that requires prompt intervention and surveillance due to the possibility of distant metastases arising in up to 50% of patients. Emergency department diagnosis of UM may be confounded by features of other intraocular pathology, such as increased ocular pressure or the finding of retinal detachment on fundoscopy. When emergency providers encounter glaucoma or retinal detachment on physical exam, point-of-care ultrasonography represents a key adjunct in the timely diagnosis and referral of this potentially vision- and life-threatening malignancy.
Nebulized Tranexamic Acid in Secondary Post-Tonsillectomy Hemorrhage: Case Series and Review of the Literature
Authors: Dermendjieva Mira , Gopalsami Anand , Glennon Nicole , Torbati Sam
Published: August 2021

Introduction: Post-tonsillectomy hemorrhage is a serious postoperative complication, and its acute management can present a challenge for the emergency provider. Although various strategies have been proposed, guidance on the best approach for management of this condition in the emergency department (ED) setting remains limited. Anecdotal reports of the use of nebulized tranexamic acid (TXA) for management of tonsillar bleeding have emerged over the past two years. Two recently published case reports describe the successful use of nebulized TXA for stabilization of post-tonsillectomy hemorrhage in an adult and a pediatric patient. Case Series: Eight patients who presented to our ED with secondary post-tonsillectomy hemorrhage received nebulized TXA for hemostatic management. The most common TXA dose used was 500 milligrams, and all but one patient received a single dose of the medication in the ED. Hemostatic benefit was observed in six patients, with complete bleeding cessation observed in five cases. Interventions prior to nebulized TXA administration were attempted in three of the six patients and included ice water gargle, direct pressure with TXA-soaked gauze, and nebulized racemic epinephrine. All but one of the patients were taken to the operating room for definitive management after initial stabilization in the ED. Conclusion: Nebulized TXA may offer a hemostatic benefit and aid in stabilization of tonsillectomy hemorrhage in the acute care setting, prior to definitive surgical intervention. Consideration of general principles of nebulization and aerosol particle size may be an important factor for drug delivery to the target tissue site.
Acute Hemiballismus as the Initial Manifestation of Ischemic Stroke: A Case Report
Authors: Huang Huiling , Goh Siang-Hiong
Published: August 2021

Introduction: Cerebrovascular disease often presents with “negative” symptoms such as weakness with reduced movement of body parts or sensory loss. Rarely do “positive” symptoms such as abnormal movements manifest in acute stroke, with hemichorea being a very rare manifestation. Case Report: This is a case report of a 62-year-old chronic smoker with no known past medical history who presented with choreatic movements of his arm and leg. Magnetic resonance imaging of the brain showed changes consistent with an infarct in the right centrum semiovale. He was treated with dual antiplatelets and was noted to have subsequent improvement in symptoms. Conclusion: Recognition and awareness of stroke presenting as movement disorders in the emergency department can help prevent delays in diagnosis and treatment.
Accuracy and Reproducibility of Frozen Section Diagnosis in Ovarian Tumors
Authors: Zaiem Feras , Deirawan Hany , Kherallah Raghad , Fehmi Omar , Jang Hyejeong , Kim Seongho , Bandyopadhyay Sudeshna , Ali-Fehmi Rouba
Published: August 2021

Context.—

Intraoperative consultation—frozen section diagnosis (FSD)—determines tumor pathology and guides the optimal surgical management of ovarian neoplasms intraoperatively.

Objective.—

To evaluate the diagnostic accuracy of the FSD and analyze the discrepancy between the FSD and final diagnosis.

Design.—

This is a retrospective study of 618 ovarian neoplasm FSDs from 2009 to 2018 at a tertiary health care center. The discrepant cases were reviewed and reevaluated by gynecologic and general surgical pathologists. The outcomes of interest were performing unnecessary procedure, returning for a second surgery, and 30-day postoperative mortality.

Results.—

The sensitivity and the positive predictive value of the FSD were lower in borderline tumors than in benign and malignant epithelial ovarian tumors. Major and minor discrepancies were identified in 5.3% (33 of 618) and 12.3% of (76 of 618) cases, respectively. A root cause analysis of the major discrepant cases showed that sampling error accounted for 43% (14 of 33). The discrepancy distributions of gynecologic and general surgical pathologists were statistically similar in the overall cohort (P = .65). The overall κ for diagnostic agreement among gynecologic pathologists, general surgical pathologists, and final diagnosis was 0.18 (0.10–0.26, P < .001), implying only a slight overall agreement. Of the major discrepant cases, only 3 had a clinical implication. One overdiagnosed patient underwent an unecessary procedure, and 2 underdiagnosed patients were recommended to return for a second surgery. No patient had 30-day postoperative mortality.

Conclusions.—

Frozen section diagnosis remains a definitive diagnostic tool in ovarian neoplasms and plays a crucial role in guiding intraoperative surgical management.
The protection of confidential communication between a lawyer and a client in the case law of the European Court of Human Rights
Authors: Đukić Dimitrije
Published: August 2021

Confidentiality of communication is a very important human right that gains in importance when the communication is conducted between a lawyer and a client. Namely, for a lawyer to be able to adequately represent their client, the client must be sure that the information they entrust to the lawyer will not reach third parties, i.e. that the communication will remain confidential. In this sense, protecting the confidentiality of communication between a lawyer and a client is very important not only for representing the client in each case, but also for the proper functioning of the legal system. This paper aims to establish which articles of the European Convention protect the right to a confidential communication between a lawyer and a client and how this communication is protected in practice by the European Court of Human Rights. The paper also examines whether it is possible to prescribe a measure by which such an important right as the right to privileged and confidential communication between a lawyer and a client could be limited and if so under what conditions.
Initiating the reorganization procedure according to the law on bankruptcy: Reorganization vs. prepackaged reorganization plan
Authors: Kajević Amina
Published: August 2021

This paper discusses the initiation of the reorganization procedure by comparing the initiation of the "classic" type of reorganization and the initiation of the reorganization in accordance with the prepackaged reorganization plan. The analysis of the initiation of these two types of reorganization will be conducted based on an overview of the three elements most important for the initiation of the reorganization procedure within one legal system; namely, when the reorganization procedure is initiated, who is authorized to initiate this procedure and what the mandatory content of the reorganization plan is. The way in which these three elements are arranged can significantly affect the quality of the reorganization plan and its successful implementation. The aim of this paper is to analyze the initiation of two types of reorganization in the Serbian Law on Bankruptcy by comparing these three elements, as well as to point out some controversial issues that arise when initiating these two proceedings.
Managing stress in migrant children in school
Authors: Vuković Snežana
Published: August 2021

Starting from basic theoretical insights into stress, the paper presents some techniques and ways of recognizing stress in migrant students, the competencies teachers need in order to work with children who are in a state of stress due to their migrant situation, and also some strategies, techniques and activities that should be implemented in the process of managing stress in migrant students in the education system. Particular emphasis is placed on the various forms of support for schools developed by the Ministry of Education, Science and Technological Development of the Republic of Serbia. In this context the paper presents: The Professional Guidelines for the Inclusion of Refugee Students into the Education System, The Training Program for Reducing Stress in Migrant Situations through the implementation of these guidelines, as well as some results of the evaluation of the Program. In view of this, the paper highlights the importance of support for work with migrant children which the education system needs to provide to schools, and maps out some future activities that could contribute to this.
Testing RFoF link for transmitting HF-OTHR signal between transmitter and receiver shelters
Authors: Petrović Pavle , Džolić Bojan , Lekić Nikola , Grbić Nemanja , Ćupurdija Ana , Orlić Vladimir , Erić Miljko
Published: August 2021

HF-OTHR site contains two equipment shelters, up to 1 km away from each other, that need to be connected for transmitting a FMCW signal. This connection, if realized using a coaxial cable, has shown itself to be vulnerable to external electromagnetic discharges, which can damage the sensitive radar equipment. This paper explores and tests the possibility of using Radio-Frequency-over-Fiber (RFoF) link as an alternative to a coaxial cable for transmission of signal, in order to ensure the immunity from external sources of electromagnetic interference (EMI).
Cryptospatial blockchain sharia hotel based on practical Byzantine fault tolerance
Authors: Suryana Moch , Wibowo Achmad , Izuddin Andik , Muslihul Amin , Bimo Gumelar , Teguh Sulistyono
Published: August 2021

This research develops an application based on android that uses four interconnected nodes in a network with the Practical Byzantine fault tolerance (PBFT) blockchain method to value object geospatial retrieval. First, this application uses two types of users, general users and surveyors. Second, a surveyor location is validated within a radius of fifty meters from the central point of assets location using midpoint circle validation. Third, PBFT is used to access and validate and guarantee consistency by data using JSON-DIFF algorithm.
Towards the Operative Objects of Post-Capitalism: A Critical Cultural- And Media-Theoretical Refusal on the Chilean Case (1973-2023)
Authors: Cotoras Straub Dusan , Zerené Harcha Joaquín , Gómez-Venegas Diego
Published: August 2021

This essay aims to unfold a refusal on what we understand have been the historical hegemonic modes of social and cultural research under capitalist realism; that is, the politico-economic system ruling the West and beyond since the 1970s onwards. To do so, we present an updated approach to analyze Chilean social and cultural history during this period, insofar as it is, we argue, a paradigmatic case to critically understand capitalist realism in general. Thus, the essay is formed by three main parts: a) a historical presentation and contextualization of the case in that period, deployed in three fragments; b) the development of a critical cultural- and media-theoretical set of concepts that are instrumental to analyze the case; and c) a proposal that allows us to project the analysis’ insights towards the present and beyond. Particularly from this latter part, but more clearly in a final short conclusion, the proposal and its potential stems from a theory-fiction approach.
Con(fuse)ing and Re(fusing) Barriers
Authors: MELT  , Britton Loren , Paehr Isabel
Published: August 2021

In "Con(fuse)ing and Re(fusing) Barriers", we activate the practice of coalescing to discuss and propose trans* and neuroqueer ways of refusing access barriers and normative expectations. Drawing from trans* feminism, crip technoscience, embodied experiences and our arts-design practice as MELT, we attend to ritual making as a crip and trans* site of resistance. Rituals are activated throughout the text as practices that reduce access barriers, change habits, slow things down, or enact community rites of passage. We refuse (as in: fuse again) and confuse (as in: reconsider assumptions) separability, and trace how materials unfold in our arts-design experiments: concrete and errors become soft, rituals disorder normative space, and cosmic rays embrace neuroqueer understandings of computing. This text is an invitation to share and embrace rituals and refusal as interrelated modes that can make space for other worlds.
Activiste, révolutionnaire, féministe : Angela Davis et le féminisme noir
Authors: Harpin Tina
Published: August 2021

Icône du Black Power et de la Révolution dans les années 1970, Angela Davis est une figure incontournable de l’activisme et du féminisme, toujours engagée dans la lutte pour la justice sociale. Cet article vise à cerner la place de cette intellectuelle militante au sein du féminisme noir américain. Effectivement, Angela Davis s’est plutôt définie comme révolutionnaire ou communiste noire que comme « féministe noire ». Néanmoins, ses écrits, indissociables de ses combats, ont indéniablement participé à l’affirmation du féminisme noir : nous le montrons en analysant son autobiographie et ses recherches sur les femmes noires. Angela Davis a inspiré le féminisme noir et y a contribué par son activisme révolutionnaire et par sa praxis pionnière de l’intersectionnalité, concept et approche qu’elle continue de défendre contre un féminisme qualifié de « bourgeois ». Toutefois, elle dépasse aussi le féminisme noir dans une certaine mesure, en se plaçant à l’avant-poste d’un féminisme révolutionnaire internationaliste et radical qui se dit « abolitionniste » (du système carcéral).
Forms of Care: Chimamanda Ngozi Adichie’s Americanah (2014), Agency, and Decolonial Feminism
Authors: McCann Fiona
Published: August 2021

This article explores feminist politics in Chimimanda Ngozi Adichie’s Americanah and the ways in which it interlinks with forms of care. I tease out the author’s engagement with intersectional feminism as well as her blind spots. I situate Adiche’s work within the context of postcolonial, popular and decolonial feminism, unpacking the significance of hair and the more general question of agency. I then move to show that the poetics of care developed in the novel ultimately falls short of embracing a decolonial feminist stance due to the relative invisibility of the neo-colonial structures at work in contemporary Nigeria.
À propos de Echo de Jean-Pascal Chaigne, oeuvre créée dans le cadre du projet de recherche « Perspectives actuelles de la musique polychorale »1
Authors: Chaigne Jean-Pascal
Published: August 2021

Le 22 janvier 2020 s’est tenu à Genève le premier laboratoire du projet de recherche en création « Perspectives actuelles de la musique polychorale », réunissant notamment des étudiants de la Haute école de musique (hem) de Genève et l’ensemble Contrechamps. Jean-Pascal Chaigne, compositeur, professeur à la hem et responsable du projet, présente les résultats de sa recherche tels qu’ils se concrétisent dans sa pièce Echo, composée à cette occasion. Après avoir expliqué en quoi l’écriture polyphonique de Giovanni Gabrieli et son rapport spécifique au timbre ont inspiré un tel projet, il détaille les procédés de sa partition qui trouvent leur origine dans la musique polychorale vénitienne du xvie siècle : en l’occurrence, les propositions de diminutions ainsi que les différentes formes de polychoralité que l’on rencontre dans Echo.
Diverse methanogens, bacteria and tannase genes in the feces of the endangered volcano rabbit (Romerolagus diazi)
Authors: Montes-Carreto Leslie M. , Aguirre-Noyola José Luis , Solís-García Itzel A. , Ortega Jorge , Martinez-Romero Esperanza , Guerrero José Antonio
Published: August 2021

Background

The volcano rabbit is the smallest lagomorph in Mexico, it is monotypic and endemic to the Trans-Mexican Volcanic Belt. It is classified as endangered by Mexican legislation and as critically endangered by the IUCN, in the Red List. Romerolagus diazi consumes large amounts of grasses, seedlings, shrubs, and trees. Pines and oaks contain tannins that can be toxic to the organisms which consume them. The volcano rabbit microbiota may be rich in bacteria capable of degrading fiber and phenolic compounds.

Methods

We obtained the fecal microbiome of three adults and one young rabbit collected in Coajomulco, Morelos, Mexico. Taxonomic assignments and gene annotation revealed the possible roles of different bacteria in the rabbit gut. We searched for sequences encoding tannase enzymes and enzymes associated with digestion of plant fibers such as cellulose and hemicellulose.

Results

The most representative phyla within the Bacteria domain were: Proteobacteria, Firmicutes and Actinobacteria for the young rabbit sample (S1) and adult rabbit sample (S2), which was the only sample not confirmed by sequencing to correspond to the volcano rabbit. Firmicutes, Actinobacteria and Cyanobacteria were found in adult rabbit samples S3 and S4. The most abundant phylum within the Archaea domain was Euryarchaeota. The most abundant genera of the Bacteria domain were Lachnoclostridium (Firmicutes) and Acinetobacter (Proteobacteria), while Methanosarcina predominated from the Archaea. In addition, the potential functions of metagenomic sequences were identified, which include carbohydrate and amino acid metabolism. We obtained genes encoding enzymes for plant fiber degradation such as endo 1,4 β-xylanases, arabinofuranosidases, endoglucanases and β-glucosidases. We also found 18 bacterial tannase sequences.
A variable-rate quantitative trait evolution model using penalized-likelihood
Authors: Revell Liam J.
Published: August 2021

In recent years it has become increasingly popular to use phylogenetic comparative methods to investigate heterogeneity in the rate or process of quantitative trait evolution across the branches or clades of a phylogenetic tree. Here, I present a new method for modeling variability in the rate of evolution of a continuously-valued character trait on a reconstructed phylogeny. The underlying model of evolution is stochastic diffusion (Brownian motion), but in which the instantaneous diffusion rate (σ2)alsoevolves by Brownian motion on a logarithmic scale. Unfortunately, it’s not possible to simultaneously estimate the rates of evolution along each edge of the treeandthe rate of evolution of σ2itself using Maximum Likelihood. As such, I propose a penalized-likelihood method in which the penalty term is equal to the log-transformed probability density of the rates under a Brownian model, multiplied by a ‘smoothing’ coefficient, λ, selected by the user. λ determines the magnitude of penalty that’s applied to rate variation between edges. Lower values of λ penalize rate variation relatively little; whereas larger λ values result in minimal rate variation among edges of the tree in the fitted model, eventually converging on a single value of σ2for all of the branches of the tree. In addition to presenting this model here, I have also implemented it as part of myphytoolsR package in the functionmultirateBM. Using different values of the penalty coefficient, λ, I fit the model to simulated data with: Brownian rate variation among edges (the model assumption); uncorrelated rate variation; rate changes that occur in discrete places on the tree; and no rate variation at all among the branches of the phylogeny. I then compare the estimated values of σ2to their known true values. In addition, I use the method to analyze a simple empirical dataset of body mass evolution in mammals. Finally, I discuss the relationship between the method of this article and other models from the phylogenetic comparative methods and finance literature, as well as some applications and limitations of the approach.
INTERRELIGIOUS DIALOGUE: PROBLEMS AND PERPECTIVES: A CHRISTIAN THEOLOGICAL APPROACH
Authors: Kritzinger JNJ (Klippies)
Published: August 2021

This article present an insider’s perspective on interreligious dialogue which follows the pastoral circle proposed by Holland and Henriot. Anecdotes from experiences of dialogue constitute the element of ‘insertion’, whereas the element of ‘analysis’ is the well-known threefold distinction between exclusivism, inclusivism and pluralism. The element of ‘theological reflection’ and ‘pastoral planning’ are dispersed throughout the article. The bulk of this article consists of a discussion of interreligious dialogue as a relationship of face-to-face ‘encounter’, shoulder-to-shoulder ‘co-operation’ and back-to-back ‘truthfulness’.
Incidence and Predictors of Post-catheterisation Femoral Artery Access Vascular Complication in North Indian Population
Authors: Gupta Anil , Choudhary Sarita , Pathak Vijay , Pathak Pooja
Published: August 2021

Introduction: Vascular access-site complications following percutaneous interventions done using femoral approach, are an important cause of mortality, morbidity, prolonged stay and greater cost burden. Aim: To study the incidence and the factors which predict femoral artery access vascular complication after catheterisation in North Indian population. Materials and Methods: This was a prospective longitudinal observational study conducted at Department of Cardiology SMS Medical College at Jaipur, Rajasthan ,India between April 2016 to November 2017. All patients (n=11200) who underwent catheterisation from the femoral approach from April 2016 till November 2017 in the study institute were included. Duplex ultrasound was performed in cases with clinical suspicion of vascular complications. Clinical data and procedural variables were compared with a control group of 100 randomly selected patients. Univariate analysis and a logistic regression model for multivariate analysis for predicting independent variable was performed. Results: Femoral artery access vascular complication incidence rate was 2.05% (230). Complications rate was higher for interventional procedures (3.6%) than diagnostic procedures (1.25%). The most common vascular complication was haematoma which was seen in 1.29% (145) patients, other complication were femoral artery venous fistula seen in 0.37% (42) patients, pseudo-aneurysm in 0.41% (46) patients, acute limb ischemia in 0.1% (12) and infection in 0.09% (11) patients. It was found that advanced age (>60 years), female gender, obesity and hypertension were predictors of complication. Patients who received thrombolytic agent or low molecular weight heparin prior to procedure, use of large sheath size (7F v/s 6F) and multiple puncture to achieve femoral artery access were also independent predictors of vascular complication. Diabetes mellitus and duration of manual compression had no impact on vascular complication. Conclusion: Femoral artery access vascular complication is not uncommon following diagnostic or interventional cardiac catheterisation. The strongest predictors of vascular complication were advanced age (>60 year), female gender, overweight & obesity, hypertension, use of thrombolytic agent or anticoagulant prior to procedure, large size sheath 7F, and multiple puncture. Use of smaller sheaths, improved access techniques, safer antithrombotic therapy and use of vascular closure devices may be helpful for prevention of these vascular complications.
Tea export competitiveness and the nexus between tea export and economic growth: The cases of Bangladesh, India and Sri Lanka
Authors: Islam Md. Sayemul , Ema Nishat Sultana , Chakrobortty Sudipto , Jahan Hasneen , Hossain Md. Emran
Published: August 2021

Tea export competitiveness and the nexus between tea export and economic growth: The cases of Bangladesh, India and Sri Lanka Long since the end of the British India regime, Bangladesh, India, and Sri Lanka have produced a signifi cant volume of tea which continues to bring them invaluable foreign currency earnings through exports. Our paper explores the tea export competitiveness of these countries by employing the Revealed Symmetric Comparative Advantage (RSCA) index, and analyses the nexus between tea export and economic growth over the period from 1980 to 2018 using several dynamic econometric approaches. Results suggest that Bangladesh has lost its tea export competitiveness over the last decade. India posted moderate performance, while Sri Lanka consistently kept its dominant position. Further, the Johansen Cointegration test outcomes report no long-run relationship between tea export and economic growth across all the countries. The Granger Causality outcomes illustrate that only in Sri Lanka is it the case that tea export causes short-run economic growth. Lastly, the impulse response function projects tea export and economic growth, taking into consideration the response of each to a shock from the other. Extrapolation from the results indicate that, in contrast to the cases of Bangladesh and India (where no direct relationship was found), tea export and economic growth are intimately interconnected in Sri Lanka. This article further recommends eff ective policies so that economic growth in these countries can remain steady and that their tea industries can thrive.
Improving the technical efficiency and productivity of dairy farms in Greece
Authors: Mitsopoulos Ioannis , Tsiouni Maria , Pavloudi Aleksandra , Gourdouvelis Dimitrios , Aggelopoulos Stamatios
Published: August 2021

This paper aims to examine the current state of dairy cattle farming in Greece, to identify factors that aff ect its profitability, and to analyse the efficiency of farms, using the non-parametric Data Envelopment Analysis (DEA) method. It also assesses the economic viability of dairy cattle farms by quantifying the technical efficiency of their processes, with a view to suggesting measures that may serve to improve competitiveness. Results have shown that the mean technical efficiencies estimated for the CRS and VRS DEA approaches are 0.693 and 0.754 respectively, indicating that 30.7% and 21.6% equiproportional decreases in inputs are feasible, given the level of outputs and the production technology.
Experimental Evaluation of Thermals Performances of The Solar Dryer with Parabolic Trough Collector
Authors: Pakouzou B. Magloire , M'Bouana N. Landry , Ky M. S. Thierry , M'Boliguipa Jean , Bathiébo D. Joseph
Published: August 2021

A cylindrical-parabolic solar-thermal converter, with 0.5m2 of capture surface, was manufactured and attached to a furnace, constituting an indirect solar dryer. Thermal balances of the elements of the receiver, housed in the focal point of this collector, are settled. A campaign of vacuum tests of this dryer indicated temperatures of the heat-bearing air in natural convection, along the absorber tube (70°C) and inside the drying cage (almost 60°C,on average). The average thermal efficiency of said converter has been evaluated at 50%.The higher the efficiency, the less the converter's capture surface is required and, therefore, less investment is required. These promising results testify to the effective performance of this new dryer compared to dryers with flat collectors, whose efficiencies could not exceed 40% despite the large surface area of these collectors.
Testosterone Correlation with Low and High Density Lipoprotein in Male Type 2 Diabetics
Authors: Laghari Mubeena , Murtaza Shazia , Talpur Zuha , Hamid Mohsina , Adnan Faryal , Ahmed Arslan
Published: August 2021

Aim: To determine correlation of serum testosterone with low and high density lipoprotein in male type 2 Diabetics presenting at a tertiary care hospital of Sindh. 

Methodology: A cross sectional study, Department of Biochemistry and Department of Medicine, Liaquat University Hospital from January 2018 to February 2019. One hundred male type 2 diabetics (cases) and one hundred age matched male (control) were selected through non – probability purposive sampling. Male diagnosed cases of DM belonging to 4th to 6th decade of life was included. Blood samples were collected by venesection and sera were squeezed by centrifugation and stored at – 20 0C in refrigerators. Testosterone was estimated by the ELISA (competitive immuno- assay) assay method and blood lipids - cholesterol, triglycerides (TAGs), LDLc and HDLc by colorimetric method. Pearson`s correlation was generated on Statistical software SPSS 21.0 version (IBM, Incorp, USA) for correlation of serum testosterone with lipids fractions (P≤0.05).

Results: Age shows majority of male type 2 diabetics were in their 5th decade. We found low serum testosterone level (10.85±4.7 mmol/L) in cases compared to normal testosterone level (13.39±3.8 mmol/L) in control (P=0.0001). Pearson`s correlation shows inverse association with HDLc (r= -0.70) (P=0.0001) and positive association with LDLc (r= 0.670) (P=0.0001).

Conclusion: We found low serum testosterone in male type 2 diabetics that showed negative correlation with high density lipoprotein (HDLc) and positive correlation with low density lipoprotein (LDLc).
Pharmacoepidemiological Safety of Drugs Used in Geriatrics: A Systematic Review in Madanapalle and Punganur Region of Andhra Pradesh
Authors: Baig M. Akmal Ali , Gautam Girendra Kumar
Published: August 2021

In this study, we were provided universal considerations for the setting up and carry out of pharmacoepidemiological studies of drug use for disorders like Osteoarthritis, Hypertension, Hyperlipidemia, Hypothyroidism, Depression, and Osteoporosis in geriatric patient. The study method was focused on monitored and categorized the prescriptions of geriatrics from 650 patient in Madapalle and Puganur region of Andhra Pradesh, Identified and prepare the list of drugs, which were inappropriately prescribed and used in geriatrics by using Revised Beers criteria and also assess the Activities of Daily Living (ADL) by using Modified Barthel Index (MBI). Identify any drug-drug interactions among the drugs used in geriatrics. We were reported the adverse drug reactions appeared in geriatrics and the various treatments that the patients are received with different co-morbidity disease with the assessment of drug exposure, and ascertainment of PIM, PPO STOPP, START criteria and MBI outcomes. Characteristic of statistics sources include evaluation of complete history of drug use in elderly patient with co-morbidity condition, allowing approximate of collective exposure. Result data from beers criteria with PIM, modified barthel index are preferable, but elderly patient treatment data from reliable sources, for example, patient or pathology registries, and medical records are also considered. We present report to showed poly-pharmacy effects of drug use on elderly patient improvement and converse the need for employing STOPP and START criteria of PIM and PPO to avoid undesirable drug reaction causation. We emphasize that a study design of beers criteria always be considered and result of Modified barthel index shows the dependency rate in elderly patient. We also underline the need for Comorbidity analyses in geriatric patient and drug usage, as drug utilization in geriatric are prone to dose and number of drugs in treatment dependent. In the main, studies of Prescription analyses like polypharmacy, PIM, PPO in prescription should explore risk Geriatric patient, the present study reveal the PIM and PPO of in prescription from six hundred and fifty geriatric patient. We conclude the pharmacoepidemiological studies of elderly patient are likely to develop significantly in the coming years, due to the rising mortality of long-term drug exposures and less awareness of poly-pharmacy result, the increasing perform of multinational studies, permiting studies of rare and common disease in elderly people, types of medication and procedural development specifically addressing geriatric treatment and long-term outcomes.
An Overview on Contact Dermatitis: Simple Review
Authors: Alzahrani Shahad Abdulaziz S. , Murad Bandar Mohammed A. Abu , Alatawi Rawan Lafi S. , Alatwi Ghadah Eid M. , Alatawi Wejdan Lafi S. , Alshahrani Hezam Shalan , Alghamdi Anwar Abdullah M. , Hezam Norah Abdo A. , Alrashidi Rinad Rasheed M. , Alsharif Ahad Salamah M. , Alsharif Abeer Salamah M. , Alruwaili Alaa Nemer S.
Published: August 2021

Contact dermatitis (CD) is usually the result of cumulative exposure to sensitive irritants and accounts for 80% of all contact dermatitis cases. ICD can coexist with atopic dermatitis (AD) and allergic contact dermatitis (ACD). Patients with Alzheimer's disease and ACD may also have a lower infection threshold for ICD. Therefore, it must stand out from EA and CAD lesions. People with ICD have experienced uncontrolled tingling and burning sensations. Itching is typically manifested in patients with AD and ACD. Compared with AD and ACD, ICD lesions are usually well described. The prognosis of ICD is based on the exclusion method. Monitor patients to rule out type 1 and type 4 hypersensitivity reactions. A negative result indicates the prognosis of ICD. Management includes identifying and avoiding irritants through the normal use of emollients. Although ICD is older, it is not uncommon in some majors, and genetics and environment play a vital role in its development.
Surgical Site Infection Incidence Following Hip Surgery: A Cross-Sectional Study
Authors: Keerio Niaz Hussain , Shah Ghazanfar Ali , Afzal Tanveer , Khanzada Aftab Alam , Joyo Muhammad Rafique , Ahmed Nizam , Noor Syed Shahid
Published: August 2021

Objective: To determine the incidence of surgical site infection among patients with hip fracture and undergo a surgical procedure for management. And to spotlight on the risk factors which may lead to surgical site infection among them. Also, to look for other complications following the surgery.

Methods: This is a descriptive, correlational cross-sectional study design. The study was conducted at Orthopedic Department, Mohammad Medical College and Hospital Mirpurkhas, Pakistan for one-year duration from March 2019 to March 2020. All patients had hip fracture and received management at the department of orthopedic. All patients were adults and older than 20 years of age. Data was analyzed using SPSS program.

Results: The study included 103 patients who had hip fractures. The most frequent age group was 40-50 years. Patients had a mix of modifiable and non-modifiable risk factors for developing surgical site infection. The incidence rate of surgical site infection in this study was 3.2%. It was correlated to having hypertension and diabetes as complications.

Conclusion: This study aimed to spotlight on the SSI following hip surgeries and to look for complications and risk factors. We noticed that the SSI rate among the study populations is almost similar as the worldwide range. This is due to the agreed protocol for managing patients. However, there is a need for log-term follow up for our patient to discover the cases of delayed SSI.
Dynamic changes in the T cell receptor repertoire during treatment with radiotherapy combined with an immune checkpoint inhibitor
Authors: Öjlert Åsa Kristina , Nebdal Daniel , Snapkov Igor , Olsen Vibeke , Kidman Joel , Greiff Victor , Chee Jonathan , Helland Åslaug
Published: August 2021

Previous studies have indicated a synergistic effect between radiotherapy and immunotherapy. A better understanding of how this combination affects the immune system can help to clarify its role in the treatment of metastatic cancer. We performed T cell receptor (TCR) sequencing on 46 sequentially collected samples from 15 patients with stage IV non‐small cell lung cancer, receiving stereotactic body radiotherapy combined with a programmed cell death ligand‐1 (PD‐L1) inhibitor. TCR repertoire diversity was assessed using Rényi diversity curves and the Shannon diversity index. TCR clones were tracked over time. We found decreasing or stable diversity in the best responders, and an increase in diversity at progression in patients with an initial response. Expansion of TCR clones was more often seen in responders. Several patients also developed new clones of high abundance. This seemed to be more related to radiotherapy than to immune checkpoint blockade. In summary, we observed similar dynamics in the TCR repertoire as have been described with immunotherapy alone. In addition, the occurrence of new unique clones of high abundance after radiotherapy may indicate that radiotherapy functions as a personalized cancer vaccine.