bluuebunny/crossref_metadata_2025 huggingface dataset:
An Insight into the General Trend of Blood Group Dissemination among Local Population of Muzaffarabad
Authors: Admin OJS
Published: March 2021

Blood groups ABO and Rhesus, constituting the most principal blood group system, are of key signicance for clinical and transfusion practices and are moreover, thought to be associated with disease susceptibility.
Sensoric Quality of Zinc Fortified Parboiled Rice
Authors: Admin OJS
Published: March 2021

Zinc is essential for growth and development, cell mediated immunity, protein synthesis, skin and bone metabolism, enzyme function, gene expression and hormonal excretion. Zinc deciency is a widespread problem and the present project was designed to develop zinc fortified parboiled rice for the improvement of zinc in rice.
Prevalence of Muscle Cramps in Elderly Women
Authors: Admin OJS
Published: March 2021

Muscle cramp is common among elderly women. A cramp is a rapid, spontaneous painful contraction of a muscle causing an obvious knot inside the muscle. Cramps occur for a few minutes and are sudden. Stretching of the muscle may relief the cramps. Cramps are painful and may awake patient from sleep, as well as delay from the rest.
Correlation Between Diameter of Portal Vein and Length of Spleen in Patients with Chronic Liver Disease
Authors: Admin OJS
Published: March 2021

In recent years, Chronic Liver Disease (CLD) had become widespread, alarmingly among adults. Sonography is the main imaging methodology performed in the assessment of people with suspected liver pathologies.
Emotional and behavioral difficulties among children and adolescents with cochlear implants
Authors: Admin OJS
Published: March 2021

In most industrial nations, the rate of pediatric cochlear implantation (CI) has improved to the point where it is now the biggest response to profound and, gradually more, severe babyhood deafness.
Diagnostic Accuracy of Ultrasound in Correlation to Alkaline Phosphatase Levels in Patients with Biliary Obstructions
Authors: Admin OJS
Published: March 2021

Abdominal Ultrasonography (USG) is an appropriate initial screening method for detection of biliary tract disease the consultants sometimes encounter patients who only have findings of dilatation of the Common Bile Duct (CBD) on US without specic biliary symptoms or jaundice.
Prevalence of Low Back Pain in Computer Users of Lahore, Pakistan
Authors: Admin OJS
Published: March 2021

Low back pain is the most occurring body disorder and most important reasons of disability in the advanced states. Numerous structures in the backbone may cause low back pain which includes ligaments that join vertebral column, outer bers of the annulus fibrosis, facet joints, vertebral periosteum, paravertebral muscu-lature and fascia.
Frequency and Susceptibility Pattern of K. Pneumoniae Recovered from Human Clinical Specimens in Lahore Population
Authors: Admin OJS
Published: March 2021

Klebsiella pneumoniae is gram negative, capsulated and non-motile organism, associated with different infections causing disease in both immunocompetent and immunocompromised hosts with a vast range including urinary, respiratory and gastro intestinal tracts.
Predictive Accuracy of Doppler SystolicDiastolic Ratio of Umbilical Artery for Evaluation of IUGR in 3rd Trimester
Authors: Admin OJS
Published: March 2021

Instrauterince Growth Restriction(IUGR)
Beneficial Effects of Omega-3 Fatty Acid on Neurological Disorder and Macular Degeneration
Authors: Admin OJS
Published: March 2021

Omega-3
Sonographic Correlation Between Distal Femoral Epiphysis Ossification Centre And Gestational Age From 28 Weeks To 40 Weeks In Population Of Faisalabad City
Authors: Admin OJS
Published: March 2021

Gestational age assessment is one of the most important tool used for estimation of perinatal morbidity and mortality. Age estimation of fetus can be recorded with the help of various parameters such as biparietal diameter, abdominal circumference, head circumference, length of the kidneys, crown rump length, length of the long bones and ossification centers.
Frequency of Different Thyroid Disorders among Females Attending Sir Ganga Ram Hospital, Lahore
Authors: Admin OJS
Published: March 2021

Thyroid disorders are very common worldwide. In Pakistan too, there is a significant burden of thyroid diseases and they are prevalent mostly in women.
Diagnostic Accuracy of Anterior Draw Test and MRI for Assessing ACL Tears of the Knee
Authors: Admin OJS
Published: March 2021

Cruciate ligaments are most commonly effected by any hard force applied on them. In cruciate ligaments anterior cruciate ligaments are mostly effected. As a result of which severe pain occurs in the joint.
Accuracy of Cerebroumblical Pulsatility Index Ratio in Intrauterine Growth Restriction in Third Trimester as a Predictor of Adverse Perinatal Outcome
Authors: Admin OJS
Published: March 2021

In pregnancy, good uteroplacental circulation is most important in good fetal growth and normal pregnancy outcome. Pregnancies, along with specific risk factors, have a high incidence of complications andcomplicating in intrauterine growth restriction (IUGR).
Association between screen timing and delay language development among the toddlers and preschoolers
Authors: Admin OJS
Published: March 2021

The exact cause of language delay remain unknown but multiple predisposing factors can cause delay. During current situation the use of screen media increases among the person of every age. Screentiming can be one of the factors contributing to language delay.
Prevalence of anemia in university going girls and its ratio between hostellites and day scholars.
Authors: Admin OJS
Published: March 2021

Anemia is considered as a reduction in blood hemoglobin concentration. It is associated with micronutrient deficiency such as iron deficiency anemia. IDA has strong health implications on girls during reproductive age.
Level of Knowledge, Attitude and Practice Regarding Dental Caries Among Visitors Visiting the Dental Department of Teaching Hospitals in Lahore
Authors: Admin OJS
Published: March 2021

Knowledge, attitude and practice regarding dental caries are major risk factors in the occurrence of dental problems and their awareness has a chief role in the prevention, control and treatment of the diseaseand thus the overall health of the population.
Role of Iron Supplementation in Reducing Severity of Depression: A Review
Authors: Admin OJS
Published: March 2021

Depression is a public health disorder, ranking third after respiratory and cardiac diseases. There were many evidences that iron deficiency anemia (IDA) is one of the foremost causes regarding nutritional pointof view for depression. We reviewed these evidences that IDAlinking to depression. We identified seventeen studies in four databases including randomized-controlled trials (RCTs) and observational studies assessing the impact of IDAand iron supplementation on the risk of depression. We extracted data on the basis of sample size, geographical region, measures of depression, hemoglobin, iron levels and intake of iron supplementation and critically appraised the results from the studies. Eleven out of sixty one studies were experimental, which indicated that dietary supplementation particularly iron supplementation had an association (r − 0.19 to −0.43 and ORs 1.70–4.64) with severity of depression. Evidences showed that women of reproductive age were more vulnerable to iron deficiency anemia than other population. Low ferritin and low hemoglobin level were associated with severity of depression. Iron is an essential nutrient for all living creatures, as a cofactor of various enzymes and plays significant role in environmental stimulant for the articulation of numerous virulence factors. Many clinical problems are caused by iron deficiency. Therefore, this review intended to highlight the important role of iron supplementation in reducing the severity of depression.
Coronavirus (COVID-19): A Review of Observed Global Responses on Pandemic Situation and Guideline for Pakistan
Authors: Admin OJS
Published: March 2021

December 2019 unfolded a nameless virus, later on called COVID-19. Initially, it emerged in Chinese city of Wuhan, subsequently spread across the globe unabatedly in a short span of time. Globally, differentcountries respond to this pandemic situation differently through their strategies to control this pandemic. United States, European countries, and Iran refuted this pandemic situation and come up withless effective coping strategies that resulted in undesirable consequences. Initially, in pandemic crisis these countries remained victims of skepticism. Consequently, owing to delayed response towardsCOVID-19 pandemic they landed in chaos. On the other hand, obliged by the scourge of COVID-19 pandemic, China and Taiwan adopted rapid response to combat the virus. China and Taiwan's effectivecontainment of COVID-19 pandemic can be attributed to their past experiences of combating pandemics: “Asian flu” in 1957, “Hong Kong flu” in 1968, “Russian flu” in 1977, and “SARS-CoV” from 2002-2004. This review study comparatively summarizes global control and prevention strategies in combating COVID-19. It also brings into spotlight Pakistan's response towards the pandemic and lessons that global strategies hold in effective containment of COVID-19 pandemic.
Health Perspectives of Grape Seed Extract (GSE)
Authors: Admin OJS
Published: March 2021

From the last decade flavonoids have become very prominent in the studies related to grapes. It has also been outlined by the recent researches that the positive effects of the constituents derived from theresidues of grapes are due to the polyphenolic compounds. Grape Seed Extract (GSE) possess a wide spectrum of medicinal features to inhibit reaction of free radicals, prevent clumping of platelets, prevent inflammation etc. Apart from that GSE have gastro-protective, hepato-protective, and cardio-protective roles. It has been reveal that the residues derived from the seeds of the grapes with enhanced flavonol constituents are important to be utilized during the conditions of fungal infections as vaginal candidiasis due to candida preventing c h a r a c t e risti c s. Du e t o t h e p r e s e n c e o f proanthocyanidins grape seeds are used as a food supplement also.
DIETARY ASSESSMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS VISITING TERTIARY CARE HOSPITAL OF LAHORE
Authors: Admin OJS
Published: March 2021

Chronic obstructive pulmonary disorder (COPD) is an aggravating and major health concern throughout the world. It is estimated that in upcoming years chronic obstructive pulmonary disease will be rankedas third common reason of mortality and fifth common cause of disablement worldwide.
LEVEL OF PATIENT SATISFACTION WITH NURSING CARE IN PUBLIC SECTOR TERTIARY CARE HOSPITALS OF PESHAWAR, PAKISTAN; A CROSS-SECTIONAL DESCRIPTIVE STUDY
Authors: Admin OJS
Published: March 2021

Nurses are the vital part of each nursing care in the health care setting. Patients interact more often with nurses and rely on them for care and restoration of health during hospitalization.
COMMUNITY KNOWLEDGE OF DENGUE FEVER IN ALLAMA IQBAL TOWN, LAHORE
Authors: Admin OJS
Published: March 2021

Globally, dengue is an emerging serious public health problem with a million infections occurring annually including significant number of dengue hemorrhagic fever cases.
BIOTERRORISM – ARE WE READY TO FACE ANOTHER BIOLOGICAL WAR
Authors: Admin OJS
Published: March 2021

The bioterrorism is threatened / premeditated utilization of biological agents/ weapons including viruses, bacteria, toxins and various other microorganisms to reason deaths and/or illness in plants, animals, humans etc. As majority of the agents/products used as biological agents are zoonotics, there is major concern about the possibility to use animals as the source. Livestock owners and veterinarians may be the first among those who identify initial cases of act of bioterrorism. Biological agents can be categorized into three classes. Biological agents of category (A) can cause easy transmission from animal to human except smallpox; as it has no reservoir of animal, human to human, cause increased mortality and can cause major health impact globally. Agents in category (B) cause moderate transmission; causing moderate morbidity and low mortality. Agents in category (C) belong to characteristics which can be engineered for spreading them globally or into massive community. We lack the adequate capability for prevention of these biological attacks, but prevention measures should be taken for decreasing the risks. For restriction of access of dangerous biological weapons to population, increased laboratory testing or scrutiny for causative agents, high control for investigations and proper measurement of prevention are necessary. Along with human measures and testing, veterinary laboratories should be included in surveillance on national level.
Effects of Working Capital Management on SME Profitability: Evidence from an Emerging Economy
Authors: Sensini Luca , Vazquez Maria
Published: March 2021

This paper's main objective was to evaluate the influence of working capital management policies on Argentine agro-industrial firms' profitability. To test our hypotheses, we analyzed a sample of 326 companies selected with a stratified random method based on an economic criterion. The data was collected through a structured questionnaire. From a methodological perspective, we used the individual determinants of working capital (DSO, DSI, DPO and CCC) as independent variables, while EBITDA represented the dependent variable. Additionally, we used leverage as a control variable. To assess the impact of individual determinants on corporate profitability, we used the dynamic panel data methodology. This approach has the advantage of controlling the unobservable effects that can influence profitability and endogeneity problems. We also checked the robustness of our results. The results offer several interesting insights. In particular, the results of the variables (DSI, DPO and CCC) showed a negative relationship with firms' profitability, suggesting that investing in inventory and requesting greater extensions from suppliers leads to additional costs that cannot offset the resulting benefits.
Does Egalitarian Democracy Boost Environmental Sustainability? An Empirical Test, 1970-2017
Authors: Roeland Amber , Soysa Indra de
Published: March 2021

Many argue that the twin problems of poverty and environmental degradation are best addressed by adopting greater egalitarian processes of governance. Greater egalitarian societies apparently contain the required social trust and consensus for making hard choices and tradeoffs for achieving environmental gains. We employ novel data on egalitarian democracy, which measure the equal access of the poor to political power and societal resources, and data covering weak and strong sustainability measured by the “adjusted net savings” and several indicators of atmospheric pollution. The results suggest that greater egalitarian governance reduces weak sustainability and increases the intensity of climate-harming pollution. Regardless of democracy, other measures of social equity, such as the GINI and equal access to health and political resources, increase, not decrease, atmospheric pollution. These results are robust to estimating procedure, several alternative models, and data. While liberté, egalité and fraternité should be pursued for their own intrinsic value, meeting urgent challenges from global warming may require more targeted solutions.
Pulse Production, Consumption and Utilization in Nigeria within Regional and Global Context
Authors: Akah Nkechi P. , Kunyanga Catherine N. , Okoth Michael W. , Njue Lucy K.
Published: March 2021

Malnutrition, hunger, and poverty are still major challenges globally especially in Sub-Saharan Africa affecting most countries like Nigeria. Legumes play key roles in food and nutritional security, health, and income generation. This review highlights status of pulse production and consumption in Nigeria and need for improvement. The study involved in-depth desk review. Data sources include FAO Statistics and other publication sources. Cowpea is Nigeria’s major pulse accounting for 95.45% area and 97.55% of the pulse production in 2016-18. Nigeria is the leading global cowpea producer with 39% production in 2016-18. However, the cowpea area has been declining, with 30% loss at 1.71% yearly between 2006-08 and 2016-18. The production appreciated by 40% viewed from 1996-98 due to increase in yield; but, overall, Nigeria’s cowpea production is marked with fluctuations/stagnation. It, thus, imports to meet domestic demand. In contrast, cowpea area, yield and production received steady and remarkable positive growth in places like Niger (73% at 2.8%, 213% at 5.9%, and 428% at 8.7% annually, respectively). Per capita availability of pulses in Nigeria is over 10 times less than cereals’ and roots/tubers’; hence, pulses contribute poorly to daily calorie and protein intakes. They are mainly utilized as cooked bean and steamed/fried pastes. Low pulse consumption is seriously contributing to nutritional problems in developing countries like Nigeria. Diverse utilization, optimizing nutritional quality of the traditional dishes, and improving safety and acceptability of especially those sold as street food can enhance their consumption, production and contribution to nutritional security.
Operon Construction Containing alsS, ilvC, ilvD and kivd Genes in Esch-erichia coli for Isobutanol Production from Glucose
Authors:   Bandung Institute of Technology, School of Life Science and Technology. Lab XI, Kennardi Gabriel , Moeis Maelita ,   Bandung Institute of Technology, School of Life Science and Technology. Lab XI, Andreas Andreas ,   Lembaga Ilmu Pengetahuan Indonesia (LIPI) Bandung
Published: March 2021

Isobutanol is a biofuel considered to be a potential gasoline substitute. However, isobutanol production is difficult because there is no native organism that can produce isobutanol. A biosynthetic pathway to produce isobutanol had been designed to utilize pyruvate produced from glucose breakdown by glycolysis in Escherichia coli (E. coli). This biosynthetic pathway con-sists of acetolactate-synthase (ALS), ketol-acid reductoisomerase (KARI), dihydroxy-acid dehydratase (DHAD), alpha-ketoisovalerate decarboxylase (KDC) and alcohol dehydrogenase (ADH) enzymes. Since E. coli does not have ALS and KDC, the genes coding for the protein is needed to be cloned and overexpressed in E. coli. KARI and DHAD were overexpressed to increase the accumulation of keto acid to increase isobutanol production. Plasmid contains an operon controlled by lac pro-moter and lac operator consisting of alsS (coded ALS from Bacillus subtilis), ilvC (coded KARI from E. coli MG1655) and ilvD (coded DHAD from E. coli MG1655) genes, obtained from previous research, and operon sequences have been confirmed by DNA sequencing. kivd gene (coding KDC from Lactococcus lactis) was obtained from iGEM 2013 kit. kivd was amplified by PCR and inserted into pJET 1.2 blunt. kivd gene was then added into 3’ end of previous operon using restriction-ligation tech-nique. The plasmid constructed was then transfered into E. coli DH5α using heat shock. The recombinant genes were expressed using IPTG (isopropyl-β-D-1-thiogalactopyranoside) induction. The SDS PAGE results were inconclusive, however isobutanol was detected by Gas Chromatography Mass Spectrometry – Selected Ion Monitoring (GC-MS-SIM) from 48 hours fermenta-tion culture at 30 oC (1,17%). An operon regulated by the lac promoter-operator containing four genes for the biosynthesis of isobutanol has been constructed and cloned in E. coli. The isobutanol production was not optimal due to weak expression and repression by glucose, which was used as substrate.
E-SIBAYU: A Tele-Monitoring App for Monitoring Pregnant Mothers and Babies
Authors:   Laboratorium Rekayasa Perangkat Lunak, Kelompok Keilmuan Rekayasa Perangkat Lunak, Jurusan Teknik Informatika, Politeknik Negeri Indramayu, Jl. Raya Lohbener Lama, no. 08, Indramayu, Indonesia, 45252, Yani Mohammad , Ismantohadi Eka ,   Laboratorium Rekayasa Perangkat Lunak, Kelompok Keilmuan Rekayasa Perangkat Lunak, Jurusan Teknik Informatika, Politeknik Negeri Indramayu, Jl. Raya Lohbener Lama, no. 08, Indramayu, Indonesia, 45252, Darsih Darsih ,   Laboratorium Rekayasa Perangkat Lunak, Kelompok Keilmuan Rekayasa Perangkat Lunak, Jurusan Teknik Informatika, Politeknik Negeri Indramayu, Jl. Raya Lohbener Lama, no. 08, Indramayu, Indonesia, 45252
Published: March 2021

During last six years, Indramayu had a high number of maternal and baby deaths. Even in 2016, Indramayu was as a third rank in number of maternal and baby deaths in West Java. The main cause of this problem was that there was no system to monitor the most causes of the maternal and baby deaths. Public health office could not plan what they should do because they did not have enough information about the real circumstance of pregnant mothers during their pregnancy. For consequence, public health office could not prepare well both the first and advance aid for the pregnant mothers who had a high risk for their health. That is why we propose a system that can provide features to monitor the progress of pregnant mothers especially in terms of four main causes involving the maternal and baby deaths happened, called E-SIBAYU. E- SIBAYU is developed for both mobile and web based. The mobile based app is used by midwifes to entry the health information of pregnant mothers, while the web-based app is used by public health officers to monitor all health information of pregnant mothers. The infor-mation is not only stored in cloud but also can be visualized in graphs and charts. E-SIBAYU has been used by public health office of Indramayu since 2017, and it has shown a positive impact on the decrease of number of maternal and baby deaths in that year. This paper presents the design and implementation of a tele-monitoring app for monitoring pregnant mother and babies called E-SIBAYU. This work is an initial work of future work to develop a wearable health device that will be able to measure the blood pressure of pregnant mothers and heart rate of babies in real-time where the future device will be possible to be mass produced to support industry of e-Health technology implementation.
PEMODELAN PARAMETRIK KURVA PERTUMBUHAN EPIDEMI COVID-19 DI INDONESIA
Authors:   Badan Pusat Statistik, Fajar Muhammad
Published: March 2021

The purpose of this study is to carry out parametric modeling of the COVID-19 epidemic growth curve so that the maximum value of the cumulative COVID-19 case and the time when it reaches that maximum point can be obtained. The data used in this study is the cumulative number of COVID-19 positive confirmed cases originating from www.covid19.go.id. The method used in this study is fitting data with the Logistic and Gompertz models. The results obtained from this study are (1) the Logistic and Gompertz mod-els are very fit in modeling the COVID-19 epidemic growth curve, indicated from the value of R2 (coefficient of determination) which reaches more than 99%, (2) From the Logistics model it is obtained that the estimated amount of the maximum cumulative case at the end of the COVID-19 epidemic is 7,714 positive confirmed cases, achieved in about 82 days (22 May 2020) from 2 March 2020 when the first positive COVID-19 case was announced by the Government. (3) From the Gompertz model, it is ob-tained that the estimated maximum cumulative case at the end of the COVID-19 epidemic is 33,975 positive confirmed cases, achieved in about 152 days (30 July 2020) from 2 March 2020 when the first positive COVID-19 case was announced by the Government. From this finding, the results of this study can be used as input to the Government to take steps in controlling the spread of COVID-19
Muslimer og muslimsk praksis i København 1863-1915
Authors: Schmidt Garbi
Published: March 2021

Denne artikel beskriver et forskningsmæssigt ganske ubeskrevet blad i dansk muslimsk historie, nemlig tilstedeværelsen af muslimer og islamisk praksis i Danmark i perioden 1863-1915. Artiklen diskuterer mulige tilgange til at danne sig et kvantitativt overblik over antallet af muslimer, herunder mulige alternativer til folketællingerne. Som kvalitativt studie beskriver artiklen tilstedeværelsen af muslimer i Danmark i perioden, blandt andet som artister, deltagere i menneskeudstillinger og tæppehandlere. Artiklen giver et dybere indblik i nogle af de begravelser af tilrejsende muslimer, som fandt sted: Det var i den forbindelse, at en muslimsk praksis for alvor blev tydelig og fik pressens og offentlighedens interesse. Artiklen bygger på et større kildemateriale af forskellige typer af arkivdata, herunder folketællinger, det københavnske politis registerblade og artikler i danske dagblade.
Muslimer i Sverige under stormaktstiden
Authors: Sorgenfrei Simon
Published: March 2021

Islamforskning i Sverige är liksom på andra håll i hög grad samtidsorienterad. Samtidigt finns intressant historiskt material som rör islam och muslimer i Sverige under historisk tid. Denna artikel behandlar några av de muslimer som kom att leva i Sverige under stormaktstiden. Ambitionen är inte främst att presentera biografiska data om dessa personer, utan att diskutera källäget och vidare forskningsbehov. Ett framträdande syfte med artikeln är att uppmuntra till ytterligare islamforskning på historiskt material i svenska arkiv.
Compact Enhanced CPW-Fed Antenna for UWB Applications
Authors: Abdi H. , Nourinia J. , Ghobadi C.
Published: March 2021

This paper presents a compact antenna with co-planar waveguide (CPW) feed line for ultra-wideband (UWB) applications. The proposed antenna consists of a beveled radiating patch with wide rectangular slit at its upper side and a partial ground plane with insertion of symmetrically two-step beveled tapers at its center and sides, which provides a wide operating bandwidth. The antenna is integrated with narrow rectangular-shaped parasitic elements with different lengths placed adjacent to radiant patch to significantly enhance the impedance matching and bandwidth, especially at the upper frequencies. The measured results show an |S11| less than -10 dB bandwidth of 2.5-19.8 GHz with 155% fractional bandwidth. Simulation results are in good agreement with experimental measurements, which exhibits the validity of the proposed design approach. Moreover, the proposed CPW-fed antenna shows omnidirectional radiation patterns with stable gain within the operational range. The proposed compact antenna with low profile, light weight, large frequency bandwidth, ease of fabrication and low cost material is suitable for UWB applications.
High-Frequency Electrodynamics of Slow Moving Media Taking into Account the Specular Reflection
Authors: Grinchik N. N. , Boiprav O. V.
Published: March 2021

The paper presents the results of constructing the physical and mathematical model of high-frequency electromagnetic waves propagation in slowly moving media of finite dimensions, which takes into account the phenomena of specular reflection of these waves. The constructed model is based on formulas designed to determine the speed of electromagnetic waves propagation in slowly moving media of finite dimensions, as well as on equations designed to describe these waves. The advantageous feature of these equations is that they take into account the Fresnel drag coefficient for electromagnetic waves propagation speed. The approach to solving of these equations, as well as the approach to modeling of the process of electromagnetic waves propagation in slowly moving media of finite dimensions, based on the use of a difference scheme, in which the motion of these media is taken into account, is proposed. It has been determined that the proposed model and approaches can be used in solving problems related to the construction of receiving-transmitting paths, as well as in solving problems of aeroacoustics.
PENINGKATAN KETRAMPILAN KOMUNIKASI DENGAN PEMBUATAN NAWALA UNTUK TENAGA PENDIDIKAN DI SIDOARJO
Authors: Lesmana Fanny , Asthararianty Asthararianty , Rusdianto Monica
Published: March 2021

aktivitas di sekolah kepada publik internal maupun publik eksternal, tidak hanya secara lisan, melainkan secara tertulis. Karenanya, diperlukan sebuah ketrampilan komunikasi dalam upaya penyampaian informasi secara tertulis. Salah satu peningkatan ketrampilan komunikasi ditunjukkan melalui pembuatan Nawala sebagai salah satu media informasi yang diperlukan oleh sebuah institusi pendidikan. Dengan demikian, setiap sekolah dapat menyampaikan informasi yang diperlukan oleh khalayak. Pelatihan dan pendampingan ini diadakan bagi tenaga pendidik dari sekolah-sekolah di Kota Sidoarjo, Jawa Timur agar mereka terampil dalam membuat Nawala. Jumlah peserta pelatihan adalah 8 (delapan) orang.Pelatihan dibagi menjadi tiga sesi, yakni memahami nawala sebagai bagian dari public relations, berlatih menulis berita sederhana, kemudian dilanjutkan dengan berlatih membuat desain sederhana. Pelatihan ini dilakukan selama 10 kali, mulai dari membagikan materi perihal penulisan hingga membuat desain Nawala yang sederhana. Selanjutnya, penulis dan tim memberikan pendampingan dalam praktik pembuatan Nawala yang langsung dapat dipergunakan oleh setiap peserta. Pada akhir pelatihan dan pendampingan ini, peserta telah membuat Nawala karya sendiri. Hasil karya Nawala tersebut dicetak sehingga dapat dibagikan pada masing-masing publiknya sebagai media informasi bagi tiap institusi.@font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536870145 1107305727 0 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-536859905 -1073732485 9 0 511 0;}@font-face {font-family:"Century Schoolbook"; panose-1:2 4 6 4 5 5 5 2 3 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:647 0 0 0 159 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin-top:0cm; margin-right:0cm; margin-bottom:8.0pt; margin-left:0cm; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-fareast-font-family:Calibri; mso-bidi-font-family:"Times New Roman"; mso-ansi-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-fareast-font-family:Calibri; mso-hansi-font-family:Calibri;}div.WordSection1 {page:WordSection1;}
EDUKASI HIDUP HEMAT KEPADA SISWA TAMAN KANAK-KANAK MELALUI PROGRAM PENGABDIAN MASYARAKAT
Authors: Linawati Nanik
Published: March 2021

Setiap pribadi mengharapkan untuk senantiasa mampu mencukupi kebutuhan anggota keluarganya dalam jangka panjang sampai akhir hidupnya. Namun godaan gaya hidup konsumtif seringkali menghambat kemampuan menabung yang dalam jangka panjang berdampak pada kemampuan menyediakan dana darurat, dana pensiun, ataupun kebutuhan lain yang diperlukan di masa depan. Terkait dengan hal tersebut diperlukan edukasi “Hidup Hemat” sejak dini kepada para siswa Taman Kanak-kanak, agar kesadaran membiasakan diri untuk hidup hemat telah tertanam sejak masa anak-anak. Kegiatan Pengabdian Masyarakat memberikan kesempatan kepada para mahasiswa untuk terlibat dalam menumbuhkan kesadaran hidup hemat sejak dini kepada para siswa Taman Kanak-kanak. Tumbuhnya kesadaran hidup hemat akan menjamin kemampuan untuk menabung yang akan mampu mewujudkan kehidupan keuangan yang sejahtera dalam jangka panjang.
Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas
Authors: Chebly Alain , Ropio Joana , Peloponese Jean‐Marie , Poglio Sandrine , Prochazkova‐Carlotti Martina , Cherrier Floriane , Ferrer Jacky , Idrissi Yamina , Segal‐Bendirdjian Evelyne , Chouery Eliane , Farra Chantal , Pham‐Ledard Anne , Beylot‐Barry Marie , Merlio Jean‐Philippe , Tomb Roland , Chevret Edith
Published: March 2021

Cutaneous T‐cell lymphomas (CTCLs) are telomerase‐positive tumors expressing hTERT, although neither gene rearrangement/amplification nor promoter hotspot mutations could explain the hTERT re‐expression. As the hTERT promoter is rich in CpG, we investigated the contribution of epigenetic mechanisms in its re‐expression. We analyzed hTERT promoter methylation status in CTCL cells compared with healthy cells. Gene‐specific methylation analyses revealed a common methylation pattern exclusively in tumor cells. This methylation pattern encompassed a hypermethylated distal region from −650 to −150 bp and a hypomethylated proximal region from −150 to +150 bp. Interestingly, the hypermethylated region matches with the recently named TERT hypermethylated oncogenic region (THOR). THOR has been associated with telomerase reactivation in many cancers, but it has so far not been reported in cutaneous lymphomas. Additionally, we assessed the effect of THOR on two histone deacetylase inhibitors (HDACi), romidepsin and vorinostat, both approved for CTCL treatment and a DNA methyltransferase inhibitor (DNMTi) 5‐azacytidine, unapproved for CTCL. Contrary to our expectations, the findings reported herein revealed that THOR methylation is relatively stable under these epigenetic drugs' pressure, whereas these drugs reduced the hTERT gene expression.
CDH6‐activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers
Authors: Bartolomé Rubén A. , Robles Javier , Martin‐Regalado Ángela , Pintado‐Berninches Laura , Burdiel Miranda , Jaén Marta , Aizpurúa Carmen , Imbaud Juan I. , Casal José Ignacio
Published: March 2021

Cadherin 6 (CDH6) is significantly overexpressed in advanced ovarian and renal cancers. However, the role of CDH6 in cancer metastasis is largely unclear. Here, we investigated the impact of CDH6 expression on integrin‐mediated metastatic progression. CDH6 preferentially bound to αIIbβ3 integrin, a platelet receptor scarcely expressed in cancer cells, and this interaction was mediated through the cadherin Arginine–glycine–aspartic acid (RGD) motif. Furthermore, CDH6 and CDH17 were found to interact with α2β1 in αIIbβ3low cells. Transient silencing of CDH6, ITGA2B, or ITGB3 genes caused a significant loss of proliferation, adhesion, invasion, and lung colonization through the downregulation of SRC, FAK, AKT, and ERK signaling. In ovarian and renal cancer cells, integrin αIIbβ3 activation appears to be a prerequisite for proper α2β1 activation. Interaction of αIIbβ3 with CDH6, and subsequent αIIbβ3 activation, promoted activation of α2β1 and cell adhesion in ovarian and renal cancer cells. Additionally, monoclonal antibodies specific to the cadherin RGD motif and clinically approved αIIbβ3 inhibitors could block pro‐metastatic activity in ovarian and renal tumors. In summary, the interaction between CDH6 and αIIbβ3 regulates α2β1‐mediated adhesion and invasion of ovarian and renal cancer metastatic cells and constitutes a therapeutic target of broad potential for treating metastatic progression.
Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom
Authors: Daoudi Khadija , Malosse Christian , Lafnoune Ayoub , Darkaoui Bouchra , Chakir Salma , Sabatier Jean‐Marc , Chamot‐Rooke Julia , Cadi Rachida , Oukkache Naoual
Published: March 2021

Buthus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition of the Moroccan B. occitanus scorpion venom. Mass spectrometry‐based proteomic techniques are commonly used in the study of scorpion venoms. The implementation of top‐down and bottom‐up approaches for proteomic analyses facilitates screening by allowing a global view of the structural aspects of such complex matrices. Here, we provide a partial overview of the venom of B. occitanus scorpion, in order to explore the diversity of its toxins and hereafter understand their effects. To this end, a combination of top‐down and bottom‐up approaches was applied using nano‐high liquid chromatography coupled to nano‐electrospray tandem mass spectrometry (nano‐LC‐ESI MS/MS). The LC‐MS results showed that B. occitanus venom contains around 200 molecular masses ranging from 1868 to 16 720 Da, the most representative of which are those between 5000 and 8000 Da. Interestingly, combined top‐down and bottom‐up LC‐MS/MS results allowed the identification of several toxins, which were mainly those acting on ion channels, including those targeting sodium (NaScTxs), potassium (KScTxs), chloride (ClScTxs), and calcium channels (CaScTx), as well as antimicrobial peptides (AMPs), amphipathic peptides, myotropic neuropeptides, and hypothetical secreted proteins. This study reveals the molecular diversity of B. occitanus scorpion venom and identifies components that may have useful pharmacological activities.
Comparing radiographs with signaling improves anomaly detection of dental students: An eye‐tracking study
Authors: Eder Thésése F. , Richter Juliane , Scheiter Katharina , Huettig Fabian , Keutel Constanze
Published: March 2021

Dental students commit many errors when diagnosing radiographs. To improve performance, students were asked to compare radiographs (with and without disease or with the same disease); relevant structures were highlighted in the radiographs. In a crossover design, students were randomly assigned to two groups differing in training order: Students in the peripheral‐central‐group (N = 39) were first trained to detect anomalies in the periphery before receiving training on anomalies in the center; the trainings in the central‐peripheral‐group (N = 39) were reversed. We measured detection rates and gaze behavior before and after each training. The detection rates after the first training revealed differences in line with our expectations; moreover, when accounting for varying difficulty of the tests sets there were within‐groups improvements in the peripheral‐central group. Unexpectedly, the gaze behavior was unaffected by the intervention. We discuss shorter learning times and sequence effects as potential causes for our findings.
Reusable Biosensor Based on Differential Phase Detection at the Point of Darkness
Authors: Samdani Shilpa , Kala Abhinav , Kaurav Rishabh , Kaladharan Sruthi , Achanta Venu Gopal
Published: March 2021

A differential phase sensor based on a narrowband perfect absorber uses the phase singularity at the point of darkness (100% absorption). Herein, a structure with a top SiO2 layer is proposed that is index matched with a glass flow cell that shows the point of darkness for both s‐ and p‐polarizations. Detailed numerical results to optimize the structure, study the role of fluctuation in thickness and roughness of analyte layer show that the proposed structure has refractive index sensitivity of 147.3° RIU−1. Experimental results of launch angle independent ≈99.9% absorption in the 45°–73° range are reported, with the highest reported till date quality factor in planar narrowband absorbers of ≈42, and high figure of merit of 556 for p‐polarization. The structure also exhibits the generalized Brewster effect with a perfect absorption (≈99.99%) for s‐polarization at ≈74° angle. Experimental results are presented to demonstrate the sensor operation for two different biomolecules at the p‐polarization resonance. The configuration presented is ideal for reusable and cost‐effective biosensors.
In Situ Surface Fluorination of TiO2 Nanocrystals Reinforces Interface Binding of Perovskite Layer for Highly Efficient Solar Cells with Dramatically Enhanced Ultraviolet‐Light Stability
Authors: Hu Wanpei , Wen Zhiling , Yu Xin , Qian Peisen , Lian Weitao , Li Xingcheng , Shang Yanbo , Wu Xiaojun , Chen Tao , Lu Yalin , Wang Mingtai , Yang Shangfeng
Published: March 2021

Low‐temperature solution‐processed TiO2 nanocrystals (LT‐TiO2) have been extensively applied as electron transport layer (ETL) of perovskite solar cells (PSCs). However, the low electron mobility, high density of electronic trap states, and considerable photocatalytic activity of TiO2 result in undesirable charge recombination at the ETL/perovskite interface and notorious instability of PSCs under ultraviolet (UV) light. Herein, LT‐TiO2 nanocrystals are in situ fluorinated via a simple nonhydrolytic method, affording formation of Ti─F bonds, and consequently increase electron mobility, decrease density of electronic trap states, and inhibit photocatalytic activity. Upon applying fluorinated TiO2 nanocrystals (F‐TiO2) as ETL, regular‐structure planar heterojunction PSC (PHJ‐PSC) achieves a champion power conversion efficiency (PCE) of 22.68%, which is among the highest PCEs for PHJ‐PSCs based on LT‐TiO2 ETLs. Flexible PHJ‐PSC devices based on F‐TiO2 ETL exhibit the best PCE of 18.26%, which is the highest value for TiO2‐based flexible devices. The bonded F atoms on the surface of TiO2 promote the formation of Pb─F bonds and hydrogen bonds between F− and FA/MA organic cations, reinforcing interface binding of perovskite layer with TiO2 ETL. This contributes to effective passivation of the surface trap states of perovskite film, resulting in enhancements of device efficiency and stability especially under UV light.
An Angular Coumarinacene and Its Characteristics
Authors: Kumar Abhinav , Venkatakrishnan Parthasarathy
Published: March 2021

This paper describes the synthesis of an angular coumarinacene. Its molecular structure by single‐crystal X‐ray analysis is revealed for the first time, which noted a sandwich‐dimeric herringbone arrangement. Its solution reveals visible absorption and bright yellow‐orange emission. The pyranone‐annulated angular coumarinacene is relatively stable, both thermally and photochemically, when compared to popular acenes. Its alignment of frontier orbital energy levels dictates its possible entry into electronics.
In silico simulation of the liquid phase pressure drop through cylindrical hollow‐fiber membrane oxygenators using a modified phenomenological model
Authors: Tabesh Hadi , Rafiei Fojan , Mottaghy Khosrow
Published: March 2021

Low blood pressure drop is an important performance characteristic of a hollow‐fiber membrane oxygenator (HFMO). While the application of natural blood corresponds to complex handling procedures, the in vitro investigation of liquid pressure drop is mainly done using water or similar fluids (e.g., normal saline solution [NSS]). In this study, a comprehensive phenomenological model has been proposed to predict the liquid pressure drop through a cylindrical HFMO, considering viscous and inertial resistances in porous media, derived from literature. The results demonstrate that approaches based on Darcy–Weisbach phenomenological equation correlate the most with in vitro experimental investigations using NSS and native porcine blood, in both pediatric and adult commercially available cylindrical HFMOs. Remarkably, this study corroborates theoretically and experimentally that approaches based on Ergun semi‐empirical equation fail to predict the liquid pressure drop in cylindrical HFMOs. Moreover, it is shown that the presented phenomenological model is also applicable to cylindrical hollow‐fiber heat exchangers, and subsequently, its noticeable effect on total liquid pressure drop through cylindrical HFMOs is demonstrated. The results reveal that this component may contribute to almost half of total blood pressure drop, and therefore, it should be redesigned using other approaches than hollow fibers.
Effects of A, B, and S components on fiber length distribution, mechanical, and impact properties of carbon fiber/ABS composites produced by different processing methods
Authors: Lee Heesook , Cho Donghwan
Published: March 2021

Carbon fiber/ABS composites with different acrylonitrile, butadiene, and styrene components were produced via extrusion/injection and long fiber thermoplastic (LFT)/injection molding processes, respectively. The effect of the components on fiber length distribution, tensile, flexural, impact, and dynamic mechanical properties of the composites was investigated. The properties of carbon fiber/ABS composites produced using 12 mm‐long LFT pellets were markedly higher than those produced using extruded pellets made with 12 mm‐long chopped carbon fibers. Uses of LFT pellets were preferable to enhancing the mechanical properties of carbon fiber/ABS composites. The tensile, flexural, and dynamic mechanical properties were increased in order of ABS750sw > ABS720 ≥ ABS780 > ABS740, whereas the impact strength was increased in order of ABS740 > ABS780 > ABS720 ≈ ABS750sw. Less carbon fiber damages and less carbon fiber length degradation upon LFT processing resulted in longer fiber length distribution and higher fiber aspect ratio in the composites with LFT pellets, indicating a beneficial reinforcing effect, which was responsible for the increased mechanical properties of ABS composites, particularly with ABS750sw. The results were agreed with each other, significantly depending on the A, B, and S components, being supported by fiber length distribution, fiber aspect ratio, and fracture surfaces.
Fabrication and performance of shape‐stable phase change materials based on epoxy group crosslinking
Authors: Tao Lijuan , Chen Sai , Liu Haihui , Han Na , Li Wei , Zhang Xingxiang
Published: March 2021

Shape‐stable phase change materials (SSPCMs) have attracted increased attention as they can be used in applications such as solar energy storage materials and smart textiles. Hexadecyl acrylate (HDA) was free‐radical copolymerized with allyl glycidyl ether (AGE) to form a copolymer with epoxy groups. It was further solidified with diethylenetriamine to form a series of novel SSPCMs. HDA could be limited to a stable 3D cross‐linking network constructed from epoxy groups, giving PCM excellent shape stability. Infrared spectroscopy and hydrogen nuclear magnetic spectroscopy showed the successful fabrication of poly(hexadecyl acrylate) (PHDA) with epoxy group. The maximum enthalpies of the SSPCMs with 5 wt% AGE during heating and cooling were 86 and 86 J/g, respectively, which indicated that they have good thermal energy storage densities. The initial melting and freezing temperatures were 32 and 29°C, respectively, which were within the comfortable temperature range of human body. In addition, the thermal decomposition temperature of SSPCMs was higher than 270°C. After 50 thermal cycles, the materials still showed excellent phase change performances. Moreover, the specimen with low degree of cross‐linking had similar temperature control and thermal response capabilities to PHDA. These SSPCMs exhibited excellent thermal performance, thermal reliabilities, and stabilities. Therefore, they were expected to be applied in various applications, including solar energy storage, energy‐saving buildings, and wearable temperature control textiles.