bluuebunny/crossref_metadata_2025 huggingface dataset:
The Union State and Actual Problems of Russian- Byelorussian Integration
Authors: Shurubovich A. V.
Published: November 2019

December 8, 2019 will be the 20-eth anniversary of signing of the Treaty of creation of the Union state by the presidents of Russia and Byelorussia. The phenomenon of the Union state (US) and the road passed by it are sufficiently contradictory. On the one hand, the US is undoubtedly the most advanced integration alignment on the post-Soviet area and a pattern for other associations. For the period of forming of the US considerable progress in all spheres of cooperation has been achieved. The mutual trade volume grew from $9,3 bln in 2000 to $35,6 bln in 2018. Investment cooperation and industrial cooperation are developing, joint programs are being realized. The documents aimed at securing of equal rights of the two countries’ citizens have been signed and are being realized; military and political as well as cooperation at the regional level is developing. On the other hand, many aims of the US have not been attained, its construction has actually been frozen. The integration process evidently slips, many conceptual issues of the union construction stay unsettled. Serious contradictions between the parties on a number of important economic and political issues remain; periodically serious conflicts (“oil”, “gas”, “milk” etc.) accompanied by “information wars” and questioning the prospects of the Russian-Byelorussian integration arise. Recently Russia raises a question of the necessity to accelerate integration in the framework of the US binding it with maintenance of preferences for Byelorussia in mutual economic relations. The action program of the two countries aimed at activization of integration cooperation in the US is being prepared. However, between the parties serious differences stipulated, first of all, by unwillingness of Byelorussia to waive its sovereignty still remain. Just in the near time it will be clear whether the parties will manage to overcome these differences and start a new stage in the development of integration.
Development of Сooperation Between Kyrgyzstan and the European Union at the Present Stage
Authors: Valeeva R. A.
Published: November 2019

After the collapse of the USSR, the West received favorable conditions for promoting its geopolitical interests. Accordingly, the European Union began to establish relations with the countries of Central Asia. The EU policy in Central Asia in the early 90s of the twentieth century is characterized by the fact that Brussels concentrated its efforts on the allocation of economic assistance, the promotion of democracy and market relations. The EU policy in the Central Asian republics was based on cooperation and partnership Agreements signed with the leadership of the countries of the region. These agreements were intended to formalize the political and economic relations of the countries of the region with the EU. The role of the Central Asian countries in EU foreign policy was more clearly defined after the adoption of the European Union Strategy for Central Asia in 2007. The European Union has taken a number of steps to strengthen its position in the region. Several formats of bilateral and regional cooperation have been created, and EU representative offices have been opened in the countries of the region.Over the past decade, the European Union has significantly intensified its foreign policy in Central Asia. It expanded diplomatic ties and successfully implemented mechanisms for developing cooperation with Central Asia. In particular, it has expanded its presence in the region, successfully launching several of its strategic programs in various areas of cooperation.In 2019, the European Union adopted a new Strategy for Central Asia. This is the first radical revision of the document adopted in 2007. This indicates a desire to update the base of interac tion and to build relations with the countries of the region in a new way. The European Union pays special attention to such areas of cooperation as energy issues, global security problems and joint struggle against the threats of terrorism, Islamic fundamentalism and radical extremism, transport and infrastructure. Particular attention is paid to the prospects and problems of the EU’s interaction with the Kyrgyz Republic, which cover various aspects: political, economic, social, trade, cultural. On 19 November 2017, the European Union and the Kyrgyz Republic began negotiations to update the existing bilateral agreement, which is intended to replace the partnership and cooperation Agreement. After the completion of the negotiations, a new agreement on expanded partnership and cooperation between Kyrgyzstan and the European Union was initialed on July 6, 2019. It includes new areas of cooperation and significantly improves the regulatory framework for trade and economic relations in accordance with WTO rules and regional economic agreements. The new agreement provides for cooperation between Kyrgyzstan and the EU in areas such as: policy and reform, enhanced cooperation in foreign policy and security issues, in the areas of justice, security and freedoms, as well as in trade.
EVALUASI KINERJA PROTOTIPE ORIFICE DISCHARGE
Authors: Suhardi Suhardi Suhardi
Published: November 2019

Peralatan Orifice discharge merupakan sebuah perangkat yang digunakan untuk mengukur laju aliran air yang keluar melalui outlet dengan diameter 13mm. Aliran air yang melalui piringan berlubang ini akan mengalami kerugian tenaga sehingga menyebabkan perubahan pada parameter pengukuran debit yang menyebabkan terjadi perberbedaan antara debit aktual dengan debit teoritis. Penelitian ini bertujuan untuk mengetahui tingkat akurasi peralatan orifice discharge  dalam  simulasi pengukuran kecepatan aliran dan debit dengan berbagai tinggi air pada manometer. Penelitian dilakukan dengan pengumpulan data atau sampel dari percobaan di laboratorium  menggunakan peralatan orifice discharge. Data yang diperoleh dari pengukuran dianalisis sehingga dihasilkan kelayakan kinerja  dari peralatan tersebut. Hasil penelitian menunjukkan bahwa simulasi pengukuran debit dan kecepatan aliran air menggunakan peralatan orifice discharge  sangat akurat dengan nilai koefisien kalibarsi 0,77.
Variaciones de la relación anatómica de la arteria carótida común y la vena yugular interna. Estudio ecográfico
Authors: Umaña Perea Mauricio , García Alberto Federico , Castillo García José Luis , Bustamante Cristancho Luis Alfonso , Martínez Collazos Juan Sebastián
Published: November 2019

Introducción: La vena yugular interna es anterior o anterolateral a la arteria carótida común en las dos terceras partes de los sujetos estudiados sonográficamente, con la cabeza rotada.

Objetivo: Se examinó la asociación de diferentes variables con la ubicación anterior de la vena.

Métodos: Las ecografías se realizaron en posición supino, con la cabeza rotada hacia el lado contrario al examinado. Se visualizó transversalmente el tercio proximal del cuello, con un transductor de 7.5 mHz. La relación entre los vasos se describió de acuerdo con la proporción de la arteria cubierta por la vena. Se hicieron comparaciones univariadas con la prueba Chi2 de Pearson y un análisis multivariado de las variables candidatas a afectar las relaciones anatómicas estudiadas

Resultados: Se incluyeron 78 individuos, 44 hombres, con edad entre 17-90 años (mediana 64.0, rango= 41-73 años). Se estudió el lado derecho en 75 ocasiones y el izquierdo en 73. La vena se localizó lateral en el 24.3% (IC95% 17.4-32.2) de los vasos estudiados, anterolateral en el 33.8% (IC95%= 26.2-41.4) y anterior en el 41.9% (IC95%= 33.9-49.8). El análisis multivariado identificó: el grupo etáreo (OR= 3.7, IC95%= 2.1-6.4) y sugiere el lado izquierdo (OR= 1.7, IC95%= 0.8-3.5) y el género masculino (OR= 1.2, IC95%= 0.6-2.7), como variables asociadas con la posición anterior de la vena.

Conclusión: La ubicación anterior de la vena yugular interna respecto a la arteria carótida común aumenta gradualmente con la edad. La localización izquierda y el género masculino pueden aumentar adicionalmente esta probabilidad.
La incorporación del sistema de atención de la salud en Occidente
Authors: Gomez Pineda Floro Hermes
Published: November 2019

Se hace una reflexión, desde una perspectiva interpretativa, sobre la evolución histórica de la atención de la salud en Occidente. Se parte desde el momento en que esta se transformó en una manera de intervenir a los enfermos y en un instrumento para la curación de las enfermedades, centrándose en documentos y fuentes originales escritas que dan cuenta de resultados de investigaciones históricas, las cuales abarcan desde el siglo XV hasta hoy. Para ello, trata de comprender la atención de la salud como un cuerpo ideográfico de conocimientos, integrado por cinco piezas de un rompecabezas compuesto por: La política estatal de acumulación de hospitales implementada en España, la acumulación de las prácticas médicas en lo que hoy es Alemania, el hospital de pabellones en Inglaterra, la racionalidad nosológica en Francia y la máquina sanitaria en Estados Unidos; todos estos movimientos como productores de unos desarrollos asistenciales sanitarios estrechamente vinculados, que no son otra cosa que acciones colectivas reguladas por normas sociales en torno a la salud.
Molecular analysis of exons 8, 9 and 10 of the fibroblast growth factor receptor 2 (FGFR2) gene in two families with index cases of Apert Syndrome
Authors: Torres Lilian , Hernández Acevedo Guaberto Yesid , Barrera Alejandro , Ospina Sandra , Prada Rolando
Published: November 2019

Introduction: Apert syndrome (AS) is a craniosynostosis condition caused by mutations in the Fibroblast Growth Factor Receptor 2(FGFR2) gene. Clinical features include cutaneous and osseous symmetric syndactily in hands and feet, with variable presentations in bones, brain, skin and other internal organs.
Methods: Members of two families with an index case of Apert Syndrome were assessed to describe relevant clinical features and molecular analysis (sequencing and amplification) of exons 8, 9 and 10 of FGFR2 gen.
Results: Family 1 consists of the mother, the index case and half -brother who has a cleft lip and palate. In this family we found a single FGFR2 mutation, S252W, in the sequence of exon 8. Although mutations were not found in the study of the patient affected with cleft lip and palate, it is known that these diseases share signaling pathways, allowing suspected alterations in shared genes. In the patient of family 2, we found a sequence variant T78.501A located near the splicing site, which could interfere in this process, and consequently with the protein function
Bicarbonato de sodio versus solución salina isotónica para la prevención de la nefropatía inducida por medio de contraste: Revisión sistemática y meta-análisis
Authors: Zapata-Chica Carlos Andres , Serna-Higuita Lina Maria , Nieto-Ríos John Fredy , Casas-Arroyave Fabian David , Donado-Gómez Jorge Hernando
Published: November 2019

Introducción: La nefropatía inducida por medio de contraste es una de las causas principales de lesión renal aguda, lo cual incrementa la morbilidad y mortalidad intrahospitalaria. La nefroprotección con bicarbonato de sodio ha surgido como una estrategia preventiva, sin embargo su eficacia es controversial cuando se compara con estrategias como la hidratación con solución salina al 0.9%.Objetivo: Comparar la efectividad del bicarbonato de sodio versus la hidratación con solución salina al 0.9% en la prevención de la lesión renal aguda inducida por contraste.Métodos: Se realizó una revisión sistemática de los estudios registrados en Cochrane, Pubmed, Medline, Lilacs, Scielo Y Embase. Se incluyeron estudios aleatorizados, controlados donde se evaluó el uso de solución salina al 0.9% versus bicarbonato de sodio para prevenir la nefropatía por medio de contraste.Resultados: Se incluyeron 22 estudios (5,686 pacientes). El bicarbonato de sodio no disminuyó el riesgo de nefropatía inducida por contraste (DR= 0.00 IC 95%= -0.02-0.03; p= 0.83, I2= 0%). Tampoco se encontró diferencia significativa en la necesidad de terapia de reemplazo renal (DR= 0.00 IC 95%= -0.01-0-01, I2= 0%, p= 0.99); ni en la mortalidad (DR= -0.00, IC 95%= -0.001-0.001, I2= 0%, p= 0.51).Conclusiones: La administración de bicarbonato de sodio no es superior al suministro de solución salina al 0.9% en la prevención de nefropatía inducida por medio de contraste en pacientes con factores de riesgo. Su uso tampoco es superior en la reducción de mortalidad y el requerimiento de terapia de reemplazo renal.
Transdisciplina y la investigación en salud: Ciencia, sociedad y toma de decisiones
Authors: Méndez Fabián
Published: November 2019

Los avances significativos en la ciencia deben darse de frente a las necesidades de la sociedad y al contexto histórico de los territorios. Aunque los desarrollos tecnológicos que empezaron con la modernidad y la revolución industrial permitieron al hombre controlar los recursos de la naturaleza para ponerlos a su servicio sin límites, es evidente que la crisis de los modelos de desarrollo predominantes se manifiestan de muchas formas en la sociedad actual y con tres denominadores comunes: deterioro del ambiente, injusticia social y pobreza extrema. En consecuencia, hoy no debería ser posible pensar un avance de relevancia en el desarrollo de la ciencia sin hacer frente a los problemas ambientales globales y a las profundas injusticias sociales que aumentan en todas las escalas bajo la mirada, en muchas ocasiones impasible, de las ciencias formales.
Charcot Marie Tooth disease (CMT4A) due to GDAP1 mutation: report of a colombian family.
Authors: Martin Angela Milena , Maradei Anaya Silvia Juliana , Velasco Parra Harvy Mauricio
Published: November 2019

Background: Mutations of GDAP1 gene cause autosomal dominant and autosomal recessive Charcot-Marie-Tooth disease and more than 40 different mutations have been reported. The recessive Q163X mutation has been described in patients of Spanish ancestry, and a founder mutation in South American patients, originating in Spain has been demonstrated.Objective: We describe physical and histological features, and the molecular impact of mutation Q163X in a Colombian family.Methods: We report two female patients, daughters of consanguineous parents, with onset of symptoms within the first two years of life, developing severe functional impairment, without evidence of dysmorphic features, hoarseness or diaphragmatic paralysis. Electrophysiology tests showed a sensory and motor neuropathy with axonal pattern. Sequencing of GDAP1 gene was requested and the study identified a homozygous point mutation (c.487 C>T) in exon 4, resulting in a premature stop codon (p.Q163X). This result confirms the diagnosis of Charcot-Marie-Tooth disease, type 4A.Results: The patients were referred to Physical Medicine and Rehabilitation service, in order to be evaluated for ambulation assistance. They have been followed by Pulmonology service, for pulmonary function assessment and diaphragmatic paralysis evaluation. Genetic counseling was offered. The study of the genealogy of the patient, phenotypic features, and electrophysiological findings must be included as valuable tools in the clinical approach of the patient with Charcot-Marie-Tooth disease, in order to define a causative mutation. In patients of South American origin, the presence of GDAP1 gene mutations should be considered, especially the Q163X mutation, as the cause of CMT4A disease.
Eficacia terapéutica de esquemas de Primaquina usados como alternativa al tratamiento estándar en la prevención de recaídas por Plasmodium vivax: Una revisión sistemática y meta-análisis
Authors: Zuluaga-Idarraga Lina Marcela , Tamayo Perez Maria-Eulalia , Aguirre-Acevedo Daniel Camilo
Published: November 2019

Objetivo:Comparar la eficacia y seguridad de los esquemas de primaquina actualmente usados para prevenir las recaídas de malaria por P. vivax.Métodos:A través de una revisión sistemática se identificaron ensayos clínicos que evaluaran la eficacia y seguridad para prevenir recurrencias por P. vivax del régimen de primaquina 0.5 mg/Kg/día por 7 o 14 días comparado al régimen estándar de 0.25 mg/Kg/día por 14 días. Se determinó la eficacia de primaquina con la incidencia acumulada de recurrencias posterior a 28 días. Se estimó el riesgo relativo global con un meta-análisis de efectos fijos.Resultados:Se identificaron 7 ensayos clínicos para el régimen 0.5 mg/Kg/día/7 días que mostraron una incidencia de recurrencias entre 0% y 20% con un seguimiento de 60 a 210 días; solo 4 estudios compararon con el régimen estándar y no se encontraron diferencias en las recurrencias entre ambos esquemas (RR= 0.977; IC 95%= 0.670-1.423). Se identificaron tres ensayos clínicos que usaron el esquema 0.5 mg/Kg/día/14 días con una incidencia de recurrencias entre 1.8% y 18.0% para 330 a 365 días; solo un estudio comparó con el régimen estándar (RR= 0.846; IC 95%= 0.484-1.477). Se encontró alto riesgo de sesgo y diferencias en la conducción de los estudios incluidos.Conclusión:No hay suficiente evidencia para determinar si los regímenes de primaquina usados como alternativas al tratamiento estándar tienen mejor eficacia para prevenir las recaídas de P. vivax. Se requieren ensayos clínicos para orientar los cambios en el esquema de tratamiento de este tipo de malaria.
Objective evaluation of surgical competency for minimally invasive surgery with a collection of simple tests
Authors: González-Neira Eliana Maria , Jiménez-Mendoza Claudia Patricia , Suarez Daniel R , Rúgeles-Quintero Saúl
Published: November 2019

Objective:This study aims at determining if a collection of 16 motor tests on a physical simulator can objectively discriminate and evaluate practitioners' competency level, i.e. novice, resident, and expert.Methods:An experimental design with three study groups (novice, resident, and expert) was developed to test the evaluation power of each of the 16 simple tests. An ANOVA and a Student Newman-Keuls (SNK) test were used to analyze results of each test to determine which of them can discriminate participants' competency level.Results:Four of the 16 tests used discriminated all of the three competency levels and 15 discriminated at least two of the three groups (α= 0.05). Moreover, other two tests differentiate beginners' level from intermediate, and other seven tests differentiate intermediate level from expert.Conclusion:The competency level of a practitioner of minimally invasive surgery can be evaluated by a specific collection of basic tests in a physical surgical simulator. Reduction of the number of tests needed to discriminate the competency level of surgeons can be the aim of future research.
Small clonal B-cell population in the bone marrow as a possible tool in the diagnosis of occult primary parotid lymphoma
Authors: Romero Martha , González-Fontal Guido R. , Duarte Mónica , Saavedra Carlos , Henao-Martínez Andrés F.
Published: November 2019

Case Description:An 82-years old Hispanic woman with a past medical history significant for pulmonary thromboembolism on oral anticoagulation, rheumatoid arthritis, and hypertension developed a new onset thrombocytopenia.Clinical Findings:Small clonal B-cells populations (SCBP) also known as monoclonal B-cell lymphocytosis was found as part of the workup for an idiopathic thrombocytopenia and lead ultimately to the diagnosis of parotid primary follicular lymphoma coexisting with Warthin tumor involving the bone marrow in a small extent and oncocytic papilloma located in the maxillary sinus.Treatment and Outcome:Patient was treated with Rituximab monotherapy with improvement on her platelet count.Clinical relevance:Although it is unclear the role of this clonal cells, they may work as a possible diagnostic tool for occult lymphomas. Further prospective studies are needed to confirm this possible association.
Do we really ponder about necessity of intravenous hydration in acute bronchiolitis?
Authors: Yıldırım Şule , Kaymaz Nazan , Topaloğlu Naci , Binnetoğlu Fatih Köksal , Tekin Mustafa , Aylanç Hakan , Battal Fatih , Gönüllü Burçin
Published: November 2019

Objective:The goal was to establish the role of intravenous hydration therapy on mild bronchiolitis.Methods:This was a retrospective case control study. Infants between 1 month and 2 years of age admitted to our general pediatrics ward between June 2012 and June 2013 with a diagnosis of uncomplicated acute bronchiolitis were enrolled to the study. Hospital medical files were reviewed to get information about children personal history, symptoms of the disease, disease severity scores and their management. Patients were classified into 4 groups according to the management; nebulized short-acting β2-agonist (salbutamol) +hydration; nebulized short-acting β2-agonist (salbutamol); hydration and neither bronchodilator nor hydration. We examined length of stay in the hospital as an outcome measure.Results:A total of 94 infants were studied. There was no significant difference between groups in terms of length of stay in hospital.Conclusions:IV hydration is not effective on length of stay in hospital in mild acute bronchiolitis patients.
Information Sciences in the Schedules of Library Bibliographic Classification
Authors: Yakovleva Galina V.
Published: November 2019

Library bibliographic classification (LBC) is the national classification system of Russia. The article briefly covers the history of the LBC and presents the structure and content of new sections of the LBC schedules, reflecting the modern literature on information science, information technology and cybernetics. The author considers specific features of delimitation of literature within the sections and between other divisions of the LBC medium schedules. Cybernetics section gives the most general and modern definition of cybernetics as the science of systems organization and control. The article studies the principles of literature delimitation between cybernetics, social and economic sciences. The author determines the main place for general literature on mathematical modelling and other methods of process control simulation. The article considers the principles of delimitation from the literature using mathematical modelling as a research method. The author presents the control system as a complex of interrelated and interdependent elements that form an ordered integrity and unity. In the construction of “Informatics and information technology” section the priority is given to the literature for users. The author analyses the principles of delimitation between informatics, mathematics, technology and scientific-information activity. The sources on preparation of text and graphic documents, technical and accounting documentation are considered as information technology, and literature on study and use of computer programs for these purposes is collected in the relevant divisions on computer technology. The article studies the principles of delimitation of literature on information processes in computer networks, network equipment, etc. The author determines the main place for the literature on Internet technologies and analyses the principles of delimitation from the literature on information search as scientific-information activity, creation and programming of web sites. There is fixed the place for literature on information systems and databases, the main areas of research in the field of artificial intelligence, virtual reality and virtualization technology. “Information security” completes the section. Delimitation is carried out with the legal basis of information security and engineering protection of information. New sections of the LBC schedules have improved the classification of literature and made it more convenient to search the catalogues.
Information-Analysis Services based on Scientific News in the Academy Research Libraries
Authors: Yudina Inna G. , Bazyleva Elena A.
Published: November 2019

In the context of the development of modern information and communication environment, the top challenge of library institutions is to renew their activities and fill it with new functionalities. As science communications advance in accordance with the general evolution of the web sphere, the organization systems of information support for scientific research therefore undergo changes too. Scientific and academic libraries with their unique position in science communications are faced with the need to rethink their role and functions, with the problem of finding new ways of information and library support to research activities, and new services that meet the needs of modern scientists. Since one of the indicators for scientific institutions reporting is the number of institution references in the media, scientific libraries have begun to provide science news services. The authors consider the news information resources and services for scientific research institutions. The paper presents a brief description of news aggregator “Siberian Science News”, an information platform for distribution, storage and browsing of factual, bibliographic and full-text data. Based on this platform, staff members of the Branch of the State Public Scientific-Technological Library of the Siberian Branch of the Russian Academy of Sciences (SB RAS) have set up a service to provide specialists with information to maintain and update the online news feeds of the research institutions of the Novosibirsk Scientific Center of SB RAS. The authors note that currently, according to the preferences of subscribers, there are used two types of information-analysis reports based on media publications. The results of the conducted research allow the authors to conclude that there is a need for more active promotion of the resource “Siberian Science News” and the service for the maintenance of news information. In the case of the research institutions, the service maintains the development of their news pages and news feeds on the websites of organizations, which in turn makes the organizations more visible in science communication environment and promotes research areas and scientific results.
Rural Libraries in China: Towards Educational and Informational Equality of Population
Authors: Barysheva Ekaterina A.
Published: November 2019

The article discusses the policy of the People’s Republic of China to expand, develop and modernize the network of rural libraries, introduce new standards of activity and innovative forms of work aimed at equalizing the imbalance between the city and village by increasing the cultural and educational level and overcoming the information poverty of local residents. The author characterizes the government programs of the People’s Republic of China in this area, adopted over the past two decades: “Cultural Information Resource Sharing Project” (2002), “Comprehensive Cultural Station Construction Project” (2006), “Farmer’s Reading Rooms Project” (2007), “Working Opinions on the Promotion of the National Art Gallery, Public Library, Cultural Centres and Stations Free to All” (2011), “Public Electronic Reading Room Construction Plan” (2012), “Support Plan for Libraries in Poor Areas” (2014), as well as the “Plan for Modernizing the System of Providing Public Services in the Sphere of Culture” and the “National Program for Promoting Reading” for 2015—2020. The article considers the structure of the library network in rural regions of China and the functions of its structural units, financing and human resources of rural libraries, the organization of stationary and extension library services, the requirements for premises, collections, technical equipment and the provision of remote access to information sources. Special attention is paid to the implementation of programs in rural regions of the country to promote digital reading and connect libraries to the services of the National Digital Library (under the guidance of the National Library of China). The article outlines the main problems existing in rural libraries of the People’s Republic of China, and the ways of their solution proposed by Chinese specialists. The author emphasizes that the Chinese experience may be of interest to Russia, taking into account the challenges facing our country in sustainable development of rural areas, which is not feasible without improving the standard of living of the rural population and providing it with high-quality educational, cultural and information services.
Young Adults and Reading in the Focus of the Regional University of Culture
Authors: Kuchmurukova Ekaterina A. , Rinchinova Yuliya S. , Shanginova Galina А. , Fokicheva Irina A.
Published: November 2019

The article considers the work of the Department of Library-Information Resources (LIR) of the East-Siberian State Institute of Culture (VSGIK), aimed at supporting the reading of young people. The purpose of this article is to reveal the experience of the Department of Library-Information Resources in the implementation framework of the project “Self-realization of young people in the journalistic creativity as the basis of psychological preventive health care”. The authors consider the stages of project implementation: conducting the contest of journalistic materials, publication of miscellany containing the best journalistic works of pupils of secondary schools, distribution of miscellany in school and university libraries of the Republic of Buryatia, implementation of different preventive events with VSGIK students and school pupils basing on the publication materials. The authors characterize the expert evaluation of competition works of pupils of senior school, based on the use of qualitative and quantitative criteria. The contest was held in two categories: “Best analytical materials” and “Best information materials”. The article describes the results of voting in the nomination “Popular vote Winner” in the social network “Vkontakte” on the VSGIK official web page. The authors describe the stage of work associated with publication of miscellany “On the threshold of adulthood: reflections of schoolchildren on literature, creativity and life”, which includes 28 competition works.

The article highlights the most interesting works of senior school students, rich in reasoning, reflecting the emotional state of person, empathy for the main characters and clearly expressed life positions. The miscellany received feedback from library staff of the Republic of Buryatia, Irkutsk Region, Trans-Baikal Region, which gave high assessment of the overall level of published materials and emphasized the wide readership of the publication. Based on the feedback of library specialists and school pupils, the article concludes about the main results of the project: there were created interesting creative works containing the authors’ arguments and reference to their own, though small life experience. Students revealed the role of book in their lives and disclosed how the book forms the personality of a person.

The authors present the quantitative and qualitative indicators of project performance. Distribution of the miscellany in 368 school libraries of the Republic of Buryatia makes it possible to ensure its wide application in the educational process.
Microbe Engineering of Guaia-6,10(14)-diene as a Building Block for the Semisynthetic Production of Plant-Derived (−)-Englerin A
Authors: Siemon Thomas , Wang Zhangqian , Bian Guangkai , Seitz Tobias , Ye Ziling , Lu Yan , Cheng Shu , Ding Yunkun , Deng: Zixin , Liu Tiangang , Christmann Mathias
Published: November 2019

Herein, we report the semisynthetic production of the potent transient receptor potential canonical (TRPC) channel agonist (−)-englerin A (EA), using guaia-6,10(14)-diene as the starting material. Guaia-6,10(14)-diene was systematically engineered in Escherichia coli and Saccharomyces cerevisiae using the CRISPR/Cas9 system and produced with high titers. This provided us the opportunity to execute a concise chemical synthesis of EA and the two related guaianes (−)-oxyphyllol and (+)-orientalol E. The potentially scalable approach combines the advantages of synthetic biology and chemical synthesis and provides an efficient and economical method for producing EA as well as its analogs.
Aroylacetylene Based Amino-Yne Click Polymerization toward Nitrogen Containing Polymers
Authors: Chen Xu , Hu Rong , Song Bo , Qin Anjun , Tang Ben Zhong
Published: November 2019

A highly efficient, spontaneous, and atom-economic polymerization of aroylacetylenes and amines at room temperature in air was established, and poly(β-enaminone)s with high molecular weights were produced in nearly quantitative yields. Moreover, singly E-configuration polymers can be obtained efficiently with secondary amines, while absolute Z-configuration products were prepared when using primary amines. In addition, the poly(β-enaminone)s can be degraded by primary amines in aqueous system to obtain definite compounds, proving their wide application prospects as degradable nitrogen containing polymers.
EVALUASI PROGRAM BIMBINGAN DAN KONSELING: SEBUAH STUDI PUSTAKA
Authors: Putri Arum Ekasari
Published: November 2019

Penelitian ini bertujuan untuk mengelaborasi landasan teori dan pelaksanaan evaluasi program bimbingan dan konseling di sekolah. Metode penelitian yang digunakan adalah metode penelitian kepustakaan. Metode pengumpulan data yang digunakan yakni metode dokumentasi. Teknik analisis data yang digunakan adalah analisis isi. Untuk menjaga ketepatan pengkajian dan mencegah kesalahan informasi dalam analisis data maka dilakukan pengecekan antar pustaka dan membaca ulang pustaka. Tujuan penelitian ini adalah untuk menyusun landasan teori dan pelaksanaan program bimbingan dan konseling. Hasil penelitian ini adalah terelaborasinya landasan teori dan pelaksanaan program bimbingan dan konseling secara utuh meliputi: 1) pengertian evaluasi program, 2) komponen program bimbingan dan konseling, 3) pengertian evaluasi program bimbingan dan konseling, 4) manfaat melaksanakan evaluasi program bimbingan dan konseling, 5) prosedur evaluasi program bimbingan dan konseling, 6) hambatan evaluasi program bimbingan dan konseling.
Performance management frente a los riesgos empresariales
Authors: Tamayo Herrera Aracely del Pilar , Mora Aristega Julio Ernesto , Troya Terranova Katherine Tatiana , Remache Silva Johanna Elizabeth
Published: November 2019

La Gestión de Riesgo Empresarial, conocida como Enterprise Risk Management (ERM) se ha relacionado con la performance y el riesgo que asumen las empresas. Las compañías que usan ERM deben mejorar la comprensión de los riesgos a nivel agregado, mejorando la eficiencia del capital invertido, la rentabilidad, la mejora de la comunicación interna y de la reducción de las asimetrías informativas. El objetivo ha sido mostrar las características administrativas y el nivel de riesgo en las organizaciones. Además, estudiar el mejoramiento de dicha gestión sobre el rendimiento de las empresas y su impacto sobre la estabilidad financiera. Se ha utilizado el método hipotético-deductivo, con enfoque analítico, fundamentadas a partir de diferentes planteamientos teóricos y estudios empíricos previos.  Los resultados obtenidos constatan que el riesgo al que se exponen las empresas depende de forma relevante de las decisiones que toman las personas implicadas en la gestión. Las conclusiones que se obtuvieron fueron que las empresas familiares se interesan en menor medida por implementar ERM salvo cuando los accionistas disponen de un mayor control de la empresa, en cuyo caso estarán más motivados a implementar sistemas de gestión del riesgo.
Dispute Resolution in International and European Law
Authors: Самович Юлия , Samovich Yulia , Шарифуллин Рамиль , Sharifullin Ramil
Published: November 2019

The textbook is a brief description of the main means of the peaceful settlement of disputes in international relations, ranging from negotiations and consultations to the features of the judicial procedure. Particular attention is paid to the protection of human rights in regional organizations, as well as judicial protection in the framework of European judicial institutions. The textbook is recommended to students in the direction of 40.04.01 "Jurisprudence" (magistracy), graduate students, students of the specialty.
Effect of impurities in the crude glycerol polymerization reaction to produce polyglycerol
Authors: Ramirez Caballero Gustavo E. , Ardila Suárez Carolina , Rojas Cristancho Jeimmy Zulay , Pineda Martínez Jennifer Paola , Ramírez García Alvaro
Published: November 2019

Crude glycerol is a low-cost biodiesel industry co-product in a ratio of 1:10 with the main product. The large quantities of crude glycerol produced affect the biodiesel and glycerol markets. Consequently, the exploration of new applications for crude glycerol becomes crucial. As the composition of crude glycerol differs significantly from that of purified glycerol, this work was focused on studying the effect of crude glycerol impurities on its polymerization, as this process, at the same reaction conditions established for the polymerization of purified glycerol, did not result in polymeric products. To identify the reason for this result, the crude glycerol was fully characterized to identify its composition. Hence, an experimental design using simulated crude glycerol was performed to study the effect of the most abundant impurities in the raw glycerol on the polymerization andthe impurities that would persist with such reaction conditions, such as soap and sodium. The response variable for the experimental design was the hydroxyl number of the reaction products. FT-IR spectroscopy was used to analyze differences among the reaction products obtained from different treatments. The presence of soap was identified as primary inhibitory factor and the bottleneck in the formation of polyglycerol via polymerization of crude glycerol. Molecular weights of the polymerization reaction products were determined and analyzed as per the MALDI-TOF technique. The identification of the effect of impurities of crude glycerol polymerization suggests new routes for using it in the production of high value-added chemicals.
Epistemologi Etika Perdagangan Internasional Dalam Konsep Alquran
Authors: Harahap Hakim Muda
Published: November 2019

Classical and contemporary interpreters such as al-Thabari, Ibnu Katsir, al-Zamakhsari, al-Maraghi, al-Zuhaili and Sayyid Quttb believe that surah Quraish is one of the verses among other verses wich proves the existence of international trade practices with all its provisions, both law, system and ethics. The presence of term at-tijarah with term al-bai and isytara is common nakirah isim which is not related to any particular trade context activy. This indicates that anything related to trade in general in the Koran is itself related to international trade. This article aimed to explore how the relevance of international trade ethics in the Quran. The reseach is a library research by using maudhui interpretation approach. The results showed that international trade etich in the Koran concept wich both display the concepts of: a) actualization of religious spiritual intelligence by aligning intentions, strong intelligence an aqility, balance of heart and mind, honesty and responsibility; b) commodity exports and imports of halal products; c) prevention of bribery and corruption in international trade; d) prevention of usury practice in international trade: e) perfecting the scales and measurements in international trade; f) prevention of the hoarding of goods in international trade; g) the application of shariah accounting in international trade; h) preventing of prohibited commodity trading practice
Masalah Yang Dihadapi Dunia Pendidikan Dengan Tutorial Online: Sebuah Short Review
Authors: Yustika Gaung Perwira , Subagyo Adam , Iswati Sri
Published: November 2019

Despite the many benefits of virtual distance learning (online), in its course distance education still has many problems. Educators and managers try to continue to improve the quality of teaching and the struggle of online class facilitators to improve the quality of distance education, but it is discovered that online class data is not the student's first choice. The results show that one of the problems in online education comes from the drop out / failure rate of students which is more common in virtual classrooms compared to traditional classes. Other studies reveal several factors such as the time needed to complete the module, lack of understanding of the context in the subject matter, problems with software accessibility, availability of reliable teachers, lack of support from the government and other reasons can create a decrease in motivation and a less conducive learning atmosphere.
Manajemen Pengembangan Kurikulum Sekolah Inklusi
Authors: Siswanto Siswanto , Susanti Eli
Published: November 2019

This study aims to explain how to develop curriculum in inclusive schools, the paradigm used in this research is the paradigm of management functions of curriculum development. Then the supporting and inhibiting factors in the process. This study uses a qualitative method using a curriculum development management approach. The data in this study were obtained through observation, in-depth interviews, and document analysis. Testing the authenticity of the data through continuous observation and triangulation of sources and methods. Data analysis uses an interactive way, including; data collection, data reduction, data presentation and conclusion drawing. The results of this study indicate that: first: the treatment given by the inclusive schools in Madrasah Aliyah Baitul Makmur towards children with different special needs is adjusted to their respective levels. For example services with regular classes with pull outs and for Madrasah Aliyah Baitul Makmur use a regular class placement / service system. Second; the development carried out at schools in Madrasah Aliyah Baitul Makmur curriculum development tailored to the characteristics / psychology of their students. The inhibiting factors are the lack of facilities and infrastructure and the absence of special teachers for children with special needs.
The Role of E-health in 24-h Monitoring of Central Haemodynamics and Vascular Function
Authors: Omboni Stefano
Published: November 2019

Recent advances in Pulse Wave Analysis (PWA) technology enable Blood Pressure (BP) measuring devices to combine the non-invasive estimation of different vascular biomarkers in ambulatory conditions. This approach allows obtaining a dynamic assessment of vascular function during the 24-h in the conditions of daily life, including night sleep. In spite of the present limited proof of the prognostic significance of 24-h ambulatory PWA, data is accumulating indicating the ability of these techniques to facilitate the early screening of vascular alterations and to improve individual Cardiovascular (CV) risk stratification. The integration of 24-h PWA with e-health and telehealth may help boost the implementation of this approach in the routine clinical evaluation of patients at risk. Telehealth-based 24-h PWA may help standardize the evaluation of recordings by making available to doctors and researchers validated analytical algorithms through dedicated web services. It may facilitate the setup of a worldwide network between expert centres and peripheral hubs in order to improve the quality of the patient’s assessment and to provide personalized care. It may establish communication between healthcare professionals and patients allowing remote monitoring and direct counselling, ultimately improving patients’ health status. The use of telehealth may also allow creating registries and collecting big-data, useful to validate and improve the quality of the algorithms, including Artificial Intelligence (AI) and Machine Learning (ML) tools for predicting patients’ risk and guide clinical care. Preliminary evidence from one of such registries (the Vascular health ASsessment Of The hypertENSive, VASOTENS Registry) seems to indicate that telehealth-based networks may be effective to collect definitive proof of the clinical utility of 24-h PWA.
Application Design for Food and Beverage Online Delivery System Based of Android Framework
Authors: Manan Abdul , Wiley Victor , Lucas Thomas
Published: November 2019

Providing good services and satisfaction to customer is main concern on online business. As technology is developed rapidly, many online restaurants has sought user-friendly platform to serve their customer. The purpose of this research is to build an Android-based online order application for online delivery restaurant. We added features of outlets distribution and product promos. We also developed a more user-friendly interface as new design. Through Waterfall development method, we design the application which based of android APP Inventor framework. Based on the assessment result of four aspect (e.g., software engineering defect, learning design, visual communication), we got average scores of 2.45, 3.40, 3.35 and 3.07. The assessment results showed that our application design is eligible to be implemented for real situation with fairly eligible score. It is recommended that the application is implemented with partial improvement especially on the software engineering debugging to get a more decent score.
Prediksi Kelulusan Tepat Waktu Menggunakan Metode C4.5 DAN K-NN (Studi Kasus : Mahasiswa Program Studi S1 Ilmu Farmasi, Fakultas Farmasi, Universitas Muhammadiyah Purwokerto)
Authors: Purwanto Eko , Kusrini Kusrini , Sudarmawan Sudarmawan
Published: November 2019

The graduation profile is one of the key elements for the accreditation standard of higher education. It mirrors the performance of the applied educational system within a period of time. The better it is, the better the accreditation will be. In support of this, a graduation prediction may be conducted to the academic database of the students. It is of pivotal to trace and classify the historical data into the data training and data testing, thus, to predict the on time-graduation. The step is importantly done to help decide the better management of learning processes. This study was therefore done to analyse certain variables applied to predict the on time-graduation using the algorythms of C.45 and K-Nearest Neighbour (K-NN). The data mining was done to the academic database of the students of the Pharmacy study programme, Pharmacy Faculty, Muhammadiyah University of Purwokerto by adding certain variables into the process. The data was then classified into the data training and data testing. Backward selection was done to select the best and most influential variables for the dataset. The study further resulted that by using the algorhythm of C.45 and backward selection, the accuracy of the graduation reached 92.75%. It is different from the acurracy the K-NN and backward selection showed that reached 96.14%. The result confirmed that the KNN showed the better accuracy than the C.45. It considerably benefitted the study programme to make better decisions on increasing the quality of services, in particular that of leraning processes.
Eponyymiset idiomit suomen kielessä
Authors: Nenonen Marja , Penttilä Esa
Published: November 2019

Eponyymiset idiomit suomen kielessä – esimerkkitapauksena presidenttiviitteiset verbilausekekonstruktiot

Suomen kielelle on tyypillistä käyttää monikkoa muissakin funktiossa kuin pelkkää useutta ilmaisemassa. Lisäksi suomen kielessä, kuten myös mm. englannissa ja ruotsissa, saatetaan erisnimiä käyttää varsinaisen käyttötarkoituksen lisäksi myös yleisnimen tapaan. Erottuakseen normaalista käytöstä erisnimi on usein kirjoitettu pienellä alkukirjaimella ja sitä käytetään monikossa.

Tässä tutkimuksessa keskitymme eponyymisiin konstruktioihin, tehdä + Nprop-PL -muotoisiin verbilausekeidiomeihin, jotka koostuvat tehdä-verbistä ja komplementista, joka on monikossa oleva erisnimi. Tyyppinä idiomi on varsin yleinen, vaikka sitä ei yleensä sanakirjoissa nähdä, koska sen merkitys on tilannesidonnainen ja pääteltävissä yleensä ainoastaan kontekstista.

Tutkimuskohteeksi on valittu Suomen tasavallan presidenttien nimen sisältävät idiomit, esim. tehdä kekkoset, tehdä tarjahaloset, tehdä Niinistöt.  Aineisto koostuu 299 idiomista, jotka on koottu internetistä.