bluuebunny/crossref_metadata_2025 huggingface dataset:
Effective wireless low‐power transmission using a phased array antenna
Authors: Park Hongwoo , Kim Hongjoon
Published: December 2014

In this study, we perform a low‐power wireless power transfer experiment to efficiently transfer energy using a phased array antenna (PAA). At the transmitting end, we used a 4 × 4 PAA consisting of left‐handed transmission line‐based compact phase shifters and inset‐feed microstrip patch antennas. The PAA used has a −30° to 30° tilting beam range with a gain ranging from 6.42 to 7.09 dBi. At the receiving end, we used an 8.9‐dBi single Yagi‐Uda rectenna at a distance of 0.8 m from the PAA and measured the converted DC powers to be between 1.5–2.2 mW for the tilting beam range. In the experiment, we limited the effective isotropically radiated power to 3 W because of concerns regarding human body safety. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:421–424, 2015
A high‐speed tunable optoelectronic oscillator with a fine step based on semiconductor optical amplifier
Authors: Chen Han , Xia Mingyu , Sun Mingming , Sun Xiaohan
Published: December 2014

An optical tunable dual‐loop optoelectronic oscillator (OEO) based on birefringence effects in a semiconductor optical amplifier (SOA) is presented and the theoretical fundamentals of the design are explained. A prototype of the OEO with a frequency of 8.8 GHz is experimentally demonstrated. About 150 MHz tunable range at X‐band with a fine step about 15 MHz is realized by directly tuning the SOA injection current, and the tuning speed can reach to over 1 GHz/µs. The generated radiofrequency (RF) signal exhibits a good stability with a single sideband phase noise lower than −101 dBc/Hz at an offset of 10 kHz within the whole tunable range, without any narrow RF band‐pass filters in the loop. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:464–467, 2015
Design and construction of miniaturized UWB microstrip antenna with slots for UWB applications
Authors: Karli Radouane , Ammor Hassan , Terhzaz Jaouad , Chaïbi Mohamed , Mediavilla Sánchez Á.
Published: December 2014

In this article, a miniaturized rectangular printed antenna that meets the ultrawideband (UWB) characteristics in terms of bandwidth and reflection coefficient is proposed. The designed antenna with dimension of 25×16 mm2 (L × W) was fabricated on FR‐4 epoxy dielectric with relative permittivity of 4.4. SMA female connector is used for feeding with characteristic impedance of 50 Ω. The antenna exhibits good UWB characteristics and has the capability of operating between 3.92 to 11.32 GHz. The proposed antenna has omnidirectional radiation pattern on most of the operating band. The measured reflection coefficient of the proposed antenna is compared with the simulated one; good agreement is observed. Also, radiation pattern and gain of the antenna are presented. All simulations are carried out using the EM commercial simulators, HFSS, and CST. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:460–463, 2015
Optical microfiber coupler based humidity sensor with a polyethylene oxide coating
Authors: Bo Lin , Wang Pengfei , Semenova Yuliya , Farrell Gerald
Published: December 2014

Optical microfiber couplers (MFCs) with certain geometries are sensitive to local refractive changes. By incorporating a humidity‐sensitive polyethylene oxide coating, a tapered optical MFC can work as a humidity sensor. We fabricated such a humidity sensor and demonstrated its sensing ability by monitoring spectral shifts in a wavelength domain. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:457–460, 2015
Microstrip‐line theory and experimental study for the characterization of the inset‐fed rectangular microstrip‐patch antenna impedance
Authors: Mbinack Clément , Tonye E. , Bajon D.
Published: December 2014

An electromagnetic approach based on the microstrip‐line theory in traveling waves was developed to validate the hypothesis of an eventual evolution of the resonant impedance of the inset‐fed rectangular patch antenna as a cos4 law as a function of the feed position. A second modeling allowing to regard the rectangular patch antenna as a plane capacitor has allowed the establishment of the reflection parameters expression of the overall studied structure using the impedance matrix concept. To end this study, the radiation pattern in 2D and 3D representation of the
electric field components in the Fraunhofer zone at 2.4 GHz is performed. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:514–518, 2015
Ka‐band antipodal fermi‐linear tapered slot antenna with a knife edge corrugation
Authors: Phalak Kiran D. , Briqech Zouhair , Sebak Abderazil
Published: December 2014

An antipodal Fermi‐linear tapered slot antenna (AFLTSA) is presented for Ka‐band applications. A substrate integrated waveguide is used to excite the tapered slot. The proposed design has a measured 26–40 GHz wide impedance bandwidth with a return loss below 15 dB. It maintains a flat gain of 16 dB over an entire frequency band. The knife edges are corrugation profile of AFLTSA exhibits side lobe level of −14 dB in H plane and −19 dB in E plane. It has a symmetric radiation pattern as well as a cross polarization level of −22 dB. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:485–489, 2015
Phase congruency on GPR data for hyperbola identification
Authors: Seyfried Daniel , Jansen Ronald , Schoebel Joerg
Published: December 2014

Evaluation of ground‐penetrating radar measurements is often done manually by an operator, which is a time‐intensive task. However, for a large number of images, an automatization of radargrams by means of digital signal processing is advantageous and demanded. An appropriate technique for automated extraction of hyperbolas' parameters, which in turn can be used to draw conclusions on the background medium's properties as well as the targets under investigation buried in ground, is, for example, among many others, the Hough transform. However, the Hough transformation is difficult to handle in real‐world scenarios due to its demanding computational requirements. In either cases, a preselection of domains potentially containing hyperbola structures is of great interest: in the case of manual evaluation, highlighting appropriate domains in the radargrams may provide visual support to the operator, hence accelerating the process. For subsequent digital signal processing, a preselection may significantly reduce processing time as only domains of interest are passed to the next processing stage. In this article, we present an approach by means of which such a preselection of domains containing hyperbola patterns can be obtained. Our approach incorporates phase congruency (PC), which yields a contrast‐independent measure for feature content; hence, it is applicable also for low‐contrast radar data corrupted by noise and clutter. Furthermore, our approach may be used to highlight appropriate features to increase their contrast utilizing PC for hyperbola identification. © 2015 Wiley Periodicals, Inc. Microwave Opt Technol Lett 57:473–478, 2015
Local projection FEM stabilization for the time‐dependent incompressible Navier–Stokes problem
Authors: Arndt Daniel , Dallmann Helene , Lube Gert
Published: December 2014

We consider conforming finite element (FE) approximations of the time‐dependent, incompressible Navier–Stokes problem with inf‐sup stable approximation of velocity and pressure. In case of high Reynolds numbers, a local projection stabilization method is considered. In particular, the idea of streamline upwinding is combined with stabilization of the divergence‐free constraint. For the arising nonlinear semidiscrete problem, a stability and convergence analysis is given. Our approach improves some results of a recent paper by Matthies and Tobiska (IMA J. Numer. Anal., to appear) for the linearized model and takes partly advantage of the analysis in Burman and Fernández, Numer. Math. 107 (2007), 39–77 for edge‐stabilized FE approximation of the Navier–Stokes problem. Some numerical experiments complement the theoretical results. © 2014 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 31: 1224–1250, 2015
Sterically Demanding Unsymmetrical Diaryl‐λ3‐iodanes for Electrophilic Pentafluorophenylation and an Approach to α‐Pentafluorophenyl Carbonyl Compounds with an All‐Carbon Stereocenter
Authors: Matsuzaki Kohei , Okuyama Kenta , Tokunaga Etsuko , Shiro Motoo , Shibata Norio
Published: December 2014

Invited for this months cover is the group of Professor Norio Shibata. The cover picture shows the Japanese painting “Genshi‐Chi” (“Primitive Land”) by Mami Shibata: our state‐of‐the‐art reagent for pentafluorophenylation is realized by the cooperation of the halogens fluorine and iodine—elements from the primitive Earth. For more details, see the Communication on 10.1002/open.201402045/full (( p. 233 ff.))
DMP1β, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer
Authors: Maglic Dejan , Stovall Daniel B , Cline J. Mark , Fry Elizabeth A , Mallakin Ali , Taneja Pankaj , Caudell David L , Willingham Mark C , Sui Guangchao , Inoue Kazushi
Published: December 2014

Our recent work has indicated that the DMP1 locus on 7q21, encoding a haplo‐insufficient tumour suppressor, is hemizygously deleted at a high frequency in breast cancer. The locus encodes DMP1α protein, an activator of the p53 pathway leading to cell cycle arrest and senescence, and two other functionally undefined isoforms, DMP1β and DMP1γ. In this study, we show that the DMP1 locus is alternatively spliced in ∼30% of breast cancer cases with relatively decreased DMP1α and increased DMP1β expression. RNA‐seq analyses of a publicly available database showed significantly increased DMP1β mRNA in 43–55% of human breast cancers, dependent on histological subtypes. Similarly, DMP1β protein was found to be overexpressed in ∼60% of tumours relative to their surrounding normal tissue. Importantly, alteration of DMP1 splicing and DMP1β overexpression were associated with poor clinical outcomes of the breast cancer patients, indicating that DMP1β may have a biological function. Indeed, DMP1β increased proliferation of non‐tumourigenic mammary epithelial cells and knockdown of endogenous DMP1 inhibited breast cancer cell growth. To determine DMP1β's role in vivo, we established MMTV‐DMP1β transgenic mouse lines. DMP1β overexpression was sufficient to induce mammary gland hyperplasia and multifocal tumour lesions in mice at 7–18 months of age. The tumours formed were adenosquamous carcinomas with evidence of transdifferentiation and keratinized deposits. Overall, we identify alternative splicing as a mechanism utilized by cancer cells to modulate the DMP1 locus through diminishing DMP1α tumour suppressor expression, while simultaneously up‐regulating the tumour‐promoting DMP1β isoform. Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Glutamic acid not beneficial for the prevention of vincristine neurotoxicity in children with cancer
Authors: Bradfield Scott M. , Sandler Eric , Geller Thomas , Tamura Roy N. , Krischer Jeffrey P.
Published: December 2014

Background

Vincristine causes known side effects of peripheral sensory, motor, autonomic and cranial neuropathies. No preventive interventions are known.

Procedure

We performed a randomized, placebo‐controlled, double‐blind trial of oral glutamic acid as a preventive agent in pediatric patients with cancer who would be receiving vincristine therapy for at least 9 consecutive weeks (Stratum 1 = Wilms tumor and rhabdomyosarcoma) or 4 consecutive weeks in conjunction with steroids (Stratum 2 = Acute lymphoblastic leukemia and non‐Hodgkin lymphoma). At designated time points, a scored neurologic exam using the Modified Balis Pediatric Scale of Peripheral Neuropathies was performed to document neurologic toxicity.

Results

Between 2007 and 2012, 250 patients were enrolled (Stratum 1 = 50, Stratum 2 = 200). The glutamic acid treated group did not have a significantly lower percentage of neurotoxicity compared to placebo treated group either overall or within stratum or age subgroups. The only subgroup which was suggestive of treatment effect was for age. Patients 13 years or older showed a larger benefit in favor of glutamic acid (P = 0.055) compared to patients less than 13 years (P = 1.00). Constipation was the most frequently reported (14%) Grade II or higher neurotoxicity.

Conclusion

Vincristine‐associated neurotoxicity in pediatric oncology remains a frequent complication of chemotherapy for multiple diagnoses with an approximate 30% of patients affected. Glutamic acid is not effective for prevention in pre‐adolescents. There is a suggestion of benefit in patients 13 years or older, but the study was not designed to provide adequate power to test the treatment effect within this age group alone. Pediatr Blood Cancer 2015;62:1004–1010. © 2014 Wiley Periodicals, Inc.
Montmorillonite–multiwalled carbon nanotube nanoarchitecture reinforced thermoplastic polyurethane
Authors: Roy Saheli , Srivastava Suneel Kumar , Pionteck Jürgen , Mittal Vikas
Published: December 2014

Montmorillonite (MMT)–multiwalled carbon nanotube (MWCNT) hybrids were prepared in different weight ratios by simple dry grinding method and characterized. Subsequently, MMT–MWCNT (1:1) hybrid was used as reinforcing filler in developing thermoplastic polyurethane (TPU) nanocomposites by solution blending method. Thermogravimetric analysis showed that 0.25 wt% hybrid‐loaded TPU nanocomposite exhibited maximum enhancement of 31°C corresponding to 50 wt% loss in thermal stability when compared with neat TPU. Differential scanning calorimetry of this composite also indicated that its crystallization and melting temperatures are enhanced by 37 and 13°C, respectively. Mechanical data showed that tensile strength and Young's modulus of 0.50 wt% filled TPU were maximum improved by 57 and 87.5%, respectively. Dynamic mechanical analysis (DMA) measurements indicated 174% (50°C) improvement in storage modulus of 0.50 wt% hybrid‐loaded TPU. Such improvements in thermal and mechanical properties have been attributed to homogeneous dispersion, strong interfacial interaction, and synergistic effect. POLYM. COMPOS., 37:1775–1785, 2016. © 2014 Society of Plastics Engineers
Medication Use Evaluation: Pharmacist Rubric for Performance Improvement
Authors: Fanikos John , Jenkins Kathryn L. , Piazza Gregory , Connors Jean , Goldhaber Samuel Z.
Published: December 2014

Despite rigorous expert review, medications often fall into routine use with unrecognized and unwanted complications. Use of some medications remains controversial because information to support efficacy is conflicting, scant, or nonexistent. Medication use evaluation (MUE) is a performance improvement tool that can be used when there is uncertainty regarding whether a medication will be beneficial. It is particularly useful when limited evidence is available on how best to choose between two or more medications. MUEs can analyze the process of medication prescribing, preparation, dispensing, administration, and monitoring. MUEs can be part of a structured or mandated multidisciplinary quality management program that focuses on evaluating medication effectiveness and improving patient safety. Successful MUE programs have a structure in place to support completion of rapid‐cycle data collection, analysis, and intervention that supports practice change.
Postmarketing Review of Intravenous Acetaminophen Dosing Based on Food and Drug Administration Prescribing Guidelines
Authors: Ubaldo Catherine dela Cruz , Hall Natalie Semaan , Le Brenden
Published: December 2014

Study Objectives

To evaluate the appropriateness of intravenous acetaminophen dosing—prescribed dose, frequency, duration, and indication—based on United States Food and Drug Administration (FDA)‐approved prescribing guidelines and to evaluate the adverse effect profile of intravenous acetaminophen.

Design

Retrospective chart review.

Setting

United States Navy medical center.

Patients

Three hundred patients who received intravenous acetaminophen from August 1, 2011, to August 1, 2012.

Measurements and Main Results

The indications, dose, frequency, and duration of intravenous acetaminophen were recorded for each patient. Adverse effects of intravenous acetaminophen were analyzed by thoroughly reviewing any adverse effects documented, including nausea, vomiting, headache, or any symptom specifically attributed to the drug. Baseline liver function tests, including aspartate aminotransferase and alanine aminotransferase levels, and elevations 3 times the upper limit of normal during intravenous acetaminophen therapy were recorded. The average patient weight was 78 ± 21 kg, with 12 patients (4%) weighing less than 50 kg and 288 (96%) patients weighing 50 kg or greater. Two hundred forty‐one patients (80%) were appropriately dosed, whereas 59 (20%) patients were not appropriately dosed based on the FDA‐approved dosing. No patients exceeded the FDA‐approved maximum daily dosing recommendations for intravenous acetaminophen (4 g). Sixty‐five patients (22%) received intravenous acetaminophen for longer than 24 hours. Intravenous acetaminophen was well tolerated, without any reported adverse effects, including the commonly reported adverse effects of nausea, vomiting, headache, and insomnia. Ten patients (3%) had a documented history of liver disease and did not experience any adverse effects or increases in liver function tests after the administration of intravenous acetaminophen.

Conclusion

Intravenous acetaminophen appeared to be a safe and effective analgesic and antipyretic agent. Dosing for patients weighing less than 50 kg needs to be appropriately weight adjusted. Intravenous acetaminophen can be used alone or in conjunction with opioids and other analgesics. Limitations of this study include its retrospective design, inability to assess outcomes of reducing opioid use, and short‐term observation period.
Unraveling the seed endosperm proteome of the lotus (Nelumbo nucifera Gaertn.) utilizing 1DE and 2DE separation in conjunction with tandem mass spectrometry
Authors: Moro Carlo F. , Fukao Yoichiro , Shibato Junko , Rakwal Randeep , Timperio Anna Maria , Zolla Lello , Agrawal Ganesh Kumar , Shioda Seiji , Kouzuma Yoshiaki , Yonekura Masami
Published: December 2014

Nelumbo nucifera (Gaertn.) or lotus, is an aquatic plant native to India, and presently consumed as food mainly in China and Japan. Lotus is also widely used in Indian and Chinese traditional medicine. Extracts from different parts of the lotus plant have been reported to show diverse biological activities—antioxidant, free radical scavenging, anti‐inflammatory, and immunomodulatory. Despite this, little work has been done in isolating and identifying proteins responsible for these activities, or yet importantly to establish a lotus proteome. The aim of our group is to develop a proteome catalog of the lotus plant, starting with its seed, the nutrient rich food source. In this present study, the seed endosperm—most abundant in proteins, and main nutrient storage tissue—was targeted for protein extraction by testing five different extraction protocols, followed by their proteomic analyses using complementary 1DE and 2DE approaches in conjunction with MS/MS. The inventory of 66 nonredundant proteins obtained by 1DE‐MS and the 30 obtained by 2DE‐MS provides the first catalog of the lotus seed endosperm, where the most abundant protein functions were in categories of metabolic activities related to carbohydrate metabolism and nutrient storage.
Evolution of Career Services in Higher Education
Authors: Dey Farouk , Cruzvergara Christine Y.
Published: December 2014

Socioeconomic changes, technological advances, and generational trends have been the impetus behind every major paradigm shift in the delivery of career services in higher education during the past century, including the one taking shape today. This chapter will provide an overview of the changing nature and emerging trends that are shaping the future of career services in higher education.
Value‐Added Career Services: Creating College/University‐Wide Systems
Authors: Garis Jeff
Published: December 2014

This chapter addresses a range of core programs that career centers can lead in contributing to an institution‐wide seamless system of career services.
The Globalization of Career Services
Authors: Kenyon Mark A. , Rowan‐Kenyon Heather T.
Published: December 2014

This chapter emphasizes the important role career services plays in advising students about global careers.
Prolonged Hypoxia Induces Monocarboxylate Transporter-4 Expression in Mesenchymal Stem Cells Resulting in a Secretome that is Deleterious to Cardiovascular Repair
Authors: Saraswati Sarika , Guo Yan , Atkinson James , Young Pampee P.
Published: December 2014

MSCs encounter extended hypoxia in the wound microenvironment yet little is known about their adaptability to this prolonged hypoxic milieu. In this study, we evaluated the cellular and molecular response of MSCs in extended hypoxia (1% O2) versus normoxia (20% O2) culture. Prolonged hypoxia induced a switch toward anaerobic glycolysis transcriptome and a dramatic increase in the transcript and protein levels of monocarboxylate transporter-4 (MCT4) in MSCs. To clarify the impact of MCT4 upregulation on MSC biology, we generated MSCs which stably overexpressed MCT4 (MCT4-MSCs) at levels similar to wild-type MSCs following prolonged hypoxic culture. Consistent with its role to efflux lactate to maintain intracellular pH, MCT4-MSCs demonstrated reduced intracellular lactate. To explore the in vivo significance of MCT4 upregulation in MSC therapy, mice were injected intramuscularly following MI with control (GFP)-MSCs, MCT4-MSCs, or MSCs in which MCT4 expression was stably silenced (KDMCT4-MSCs). Overexpression of MCT4 worsened cardiac remodeling and cardiac function whereas silencing of MCT4 significantly improved cardiac function. MCT4-overexpressing MSC secretome induced reactive oxygen species-mediated cardiomyocyte but not fibroblast apoptosis in vitro and in vivo; lactate alone recapitulated the effects of the MCT4-MSC secretome. Our findings suggest that lactate extruded by MCT4-overexpressing MSCs preferentially induced cell death in cardiomyocytes but not in fibroblasts, leading ultimately to a decline in cardiac function and increased scar size. A better understanding of stem cells response to prolonged hypoxic stress and the resultant stem cell-myocyte/fibroblast cross-talk is necessary to optimize MSC-based therapy for cardiac regeneration. Stem Cells  2015;33:1333–1344
Prospectively Isolated Human Bone Marrow Cell-Derived MSCs Support Primitive Human CD34-Negative Hematopoietic Stem Cells
Authors: Matsuoka Yoshikazu , Nakatsuka Ryusuke , Sumide Keisuke , Kawamura Hiroshi , Takahashi Masaya , Fujioka Tatsuya , Uemura Yasushi , Asano Hiroaki , Sasaki Yutaka , Inoue Masami , Ogawa Hiroyasu , Takahashi Takayuki , Hino Masayuki , Sonoda Yoshiaki
Published: December 2014

Hematopoietic stem cells (HSCs) are maintained in a specialized bone marrow (BM) niche, which consists of osteoblasts, endothelial cells, and a variety of mesenchymal stem/stromal cells (MSCs). However, precisely what types of MSCs support human HSCs in the BM remain to be elucidated because of their heterogeneity. In this study, we succeeded in prospectively isolating/establishing three types of MSCs from human BM-derived lineage- and CD45-negative cells, according to their cell surface expression of CD271 and stage-specific embryonic antigen (SSEA)−4. Among them, the MSCs established from the Lineage−CD45−CD271+SSEA-4+ fraction (DP MSC) could differentiate into osteoblasts and chondrocytes, but they lacked adipogenic differentiation potential. The DP MSCs expressed significantly higher levels of well-characterized HSC-supportive genes, including IGF-2, Wnt3a, Jagged1, TGFβ3, nestin, CXCL12, and Foxc1, compared with other MSCs. Interestingly, these osteo-chondrogenic DP MSCs possessed the ability to support cord blood-derived primitive human CD34-negative severe combined immunodeficiency-repopulating cells. The HSC-supportive actions of DP MSCs were partially carried out by soluble factors, including IGF-2, Wnt3a, and Jagged1. Moreover, contact between DP MSCs and CD34-positive (CD34+) as well as CD34-negative (CD34−) HSCs was important for the support/maintenance of the CD34+/− HSCs in vitro. These data suggest that DP MSCs might play an important role in the maintenance of human primitive HSCs in the BM niche. Therefore, the establishment of DP MSCs provides a new tool for the elucidation of the human HSC/niche interaction in vitro as well as in vivo. Stem Cells  2015;33:1554–1565
Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis
Authors: Yousef Hanadie , Morgenthaler Adam , Schlesinger Christina , Bugaj Lukasz , Conboy Irina M. , Schaffer David V.
Published: December 2014

Hippocampal neurogenesis, the product of resident neural stem cell proliferation and differentiation, persists into adulthood but decreases with organismal aging, which may contribute to the age-related decline in cognitive function. The mechanisms that underlie this decrease in neurogenesis are not well understood, although evidence in general indicates that extrinsic changes in an aged stem cell niche can contribute to functional decline in old stem cells. Bone morphogenetic protein (BMP) family members are intercellular signaling proteins that regulate stem and progenitor cell quiescence, proliferation, and differentiation in various tissues and are likewise critical regulators of neurogenesis in young adults. Here, we establish that BMP signaling increases significantly in old murine hippocampi and inhibits neural progenitor cell proliferation. Furthermore, direct in vivo attenuation of BMP signaling via genetic and transgenic perturbations in aged mice led to elevated neural stem cell proliferation, and subsequent neurogenesis, in old hippocampi. Such advances in our understanding of mechanisms underlying decreased hippocampal neurogenesis with age may offer targets for the treatment of age-related cognitive decline. Stem Cells  2015;33:1577–1588
No Longer Invisible
Authors: Thomas Cornell
Published: December 2014

In a real teaching and learning community of learners, the belief exists that all can and will learn, that the teacher has the ability to connect new information with the knowledge base of each student, and that students will become empowered to make their own connections. This premise is built on a foundation that sees each student as a unique human being with the ability to grow. They are not cloaked by some set of generalized characteristics. They are not invisible.
Addressing Racial Awareness and Color‐Blindness in Higher Education
Authors: Diggles Kimberly
Published: December 2014

Racial awareness is a critical foundation to racial sensitivity, and it is a necessity for future professionals who want to be prepared to succeed in an increasingly diverse society. Several factors have been shown to influence racial awareness in professionals including their own race, their personal experience with racism, and the amount/quality of training they receive on the topic of race. Institutions of higher education that pride themselves on preparing students to work in a global and diverse market should make a purposeful effort to teach students how to address issues related to race and racism. This chapter offers recommendations for how to transform traditional programs into programs with a focus on antiracism using a Critical Race Theory paradigm. For example, curricula should be designed to challenge students to focus on their personal experiences of racism and racial identity rather than simply studying others’. Student resistance can be minimized by recruiting faculty and students with not only racial diversity, but with diversity of experiences with racism. Finally, by purposefully engaging in interdisciplinary work on campus, smaller departments or more homogeneous departments can provide racial minority students with much needed opportunities for racial identity development and cross‐racial interactions.
The Value of Connectedness in Inclusive Teaching
Authors: Figueroa Ivan
Published: December 2014

The author addresses the importance of relationships in order for learning to take place in an inclusive manner. Anecdotes illustrate the value in beginning where the learner is and the unexpected opportunities the journey can lead to when both teacher and learner venture through unchartered paths together.
Collaborate on strategic planning for campuswide results
Authors: Hope Joan
Published: December 2014

LOS ANGELES — The University of California, San Diego recently celebrated its 50th anniversary. Another recent milestone was that officials created the institution's first strategic plan.
Embrace change to move unit forward in difficult times
Authors: Hope Joan
Published: December 2014

If you've lived through a student information system conversion, you know how difficult change can be. But organizational change is even more challenging than a SIS conversion, said Mark McConahay, associate vice provost and registrar at Indiana University at Bloomington. He's also director for the American Association of Collegiate Registrars and Admissions Officers Technology and Transfer Conference.
Prediction of delivery mode by ultrasound‐assessed fetal position in nulliparous women with prolonged first stage of labor
Authors: Eggebø T. M. , Hassan W. A. , Salvesen K. Å. , Torkildsen E. A. , Østborg T. B. , Lees C. C.
Published: December 2014

ABSTRACT

Objectives

To ascertain if fetal head position on transabdominal ultrasound is associated with delivery by Cesarean section in nulliparous women with a prolonged first stage of labor.

Methods

This was a prospective observational study performed at Stavanger University Hospital, Norway, and Addenbrooke's Hospital, Cambridge, UK, between January 2012 and April 2013. Nulliparous pregnant women with a singleton cephalic presentation at term and prolonged labor had fetal head position assessed by ultrasound. The main outcome was Cesarean section vs vaginal delivery, and secondary outcomes were association of fetal head position with operative vaginal delivery and duration of remaining time in labor.

Results

Fetal head position was assessed successfully by ultrasound examination in 142/150 (95%) women. In total, 19/50 (38%) women with a fetus in the occiput posterior (OP) position were delivered by Cesarean section compared with 16/92 (17%) women with a fetus in a non‐OP position (P = 0.01). On multivariable logistic regression analysis, the OP position predicted delivery by Cesarean section with an odds ratio (OR) of 2.9 (95% CI, 1.3–6.7; P = 0.01) and induction of labor with an OR of 2.4 (95% CI, 1.0–5.6; P = 0.05). Fetal head position was not associated with operative vaginal delivery or with remaining time in labor. The agreement between a digital and an ultrasound assessment of OP position was poor (Cohen's kappa = 0.19; P = 0.18).

Conclusion

OP fetal head position assessed by transabdominal ultrasound was significantly associated with delivery by Cesarean section. Copyright © 2014 ISUOG. Published by John Wiley & Sons Ltd.
How hot is too hot? Live‐trapped gray wolf rectal temperatures and 1‐year survival
Authors: Barber‐Meyer Shannon M. , Mech L. David
Published: December 2014

The ability of physically restrained and anesthetized wolves to thermoregulate is lessened and could lead to reduced survival, yet no information is available about this subject. Therefore, we analyzed rectal temperatures related to survival 1 year post‐capture from 173 adult (non‐pup) gray wolves (Canis lupus) captured in modified foot‐hold traps for radiocollaring during June–August, 1988–2011, in the Superior National Forest of northeastern Minnesota, USA. The maximum observed rectal temperature (“maxtemp,” ° F, ° C) in each wolf during capture ( = 104.0, 40.0; SD = 2.0, 1.1; min. = 95.9, 35.5; max. = 108, 42.2) was not a significant predictor of survival to 1 year post‐capture. Although no weather or morphometric variable was a significant predictor of maxtemps, wolves initially anesthetized with ketamine–xylazine rather than telazol®–xylazine averaged higher maxtemps. This information does not fully address possible effects of high body temperatures related to live‐capture and handling of wolves, but it does provide a useful waypoint for future assessments of this relationship and a reassurance to wildlife practitioners that the maxtemps observed in our study did not appear to affect 1‐year survival. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.
Moving beyond attendance: Lessons learned from assessing engagement in afterschool contexts
Authors: Fredricks Jennifer A. , Bohnert Amy M. , Burdette Kimberly
Published: December 2014

Youth engagement is the least researched, but potentially most important, aspect of participation in afterschool programs. The level of youth engagement can vary across programs, across youth within a program, and within individual youth over time. Engagement is important for both recruiting and retaining participants, and has been associated with more positive academic outcomes over time. This chapter integrates perspectives from practitioners, researchers, and the school engagement literature. Reasons why engagement is an important dimension of afterschool programming, different methods for assessing engagement, key features of engaging afterschool programs, and implications for practice are also outlined.
Cultural competence in afterschool programs
Authors: Simpkins Sandra D. , Riggs Nathaniel R.
Published: December 2014

Increasing ethnic diversity among American youth, in combination with funding priorities often targeting underserved populations, has increased the number of diverse youth attending afterschool programs (ASPs). At present, there is little guidance on how to best design ASPs and prepare staff to support the development of these diverse youth. The fields of medicine and education have begun to explore the impact of cultural competence at the organizational, structural, and professional levels to help bridge potential cultural divides. This chapter will briefly review the literature on cultural competence and emerging evidence within ASPs. It will then provide concrete examples of how afterschool programs have infused culturally tailored content and/or staff trainings to build cultural competence. Finally, specific recommendations will be made to serve as a springboard for future research and practice.
Expression of VH-linker-VL orientation-dependent single-chain Fv antibody fragment derived from hybridoma 2E6 against aflatoxin B1 in Escherichia coli
Authors: Liu Aiping , Ye Yang , Chen Weifeng , Wang Xiaohong , Chen Fusheng
Published: December 2014

Aflatoxin B1 (AFB1) is a toxic secondary metabolic product, which threatens human and animal health. Antibody is a key factor for immunoassay against toxic stuff like AFB1, and single-chain Fv antibody fragment (scFv) has become a popular format of genetically engineered antibody. In this study, four hybridoma cell lines against AFB1 were obtained, and then scFvs 2E6 derived from hybridoma cell line 2E6 were constructed in different VH/VL orientations. Subsequently, scFvs 2E6 were expressed in E. coli BL21(DE3) mainly in the form of inclusion body. SDS-PAGE, Western blot and ELISA were employed to characterize scFvs 2E6. The results revealed that the yield of inclusion body of scFvs 2E6 in either VH/VL orientation was similar; however, only the scFv in VH-linker-VL orientation showed anti-AFB1 bioactivity after refolding. The present study underscores the importance of choosing optimal VH/VL orientation for scFv construction, and scFv may be favorable for immunoassays in food industry.
Postinterventional microembolism signals detected by transcranial Doppler ultrasound after carotid artery stenting
Authors: Piorkowski Michael , Kläffling Christina , Botsios Spiridon , Zerweck Christoph , Scheinert Susanne , Banning-Eichenseher Ursula , Bausback Yvonne , Scheinert Dierk , Schmidt Andrej
Published: December 2014

Background: The occurrence of early post-procedural complications after carotid artery stenting (CAS) can be attributed to embolization of thrombus or plaque particles released from the stented segment. Vascular emboli can be non-invasively detected by transcranial Doppler ultrasound as microembolic signals (MES). We performed this study to discover factors predicting MES detected by transcranial Doppler (TCD)-monitoring within the early post-interventional phase. Patients and methods: In 134 consecutive patients undergoing CAS, transcranial Doppler monitoring of the ipsilateral middle cerebral artery was performed for MES detection during the first post-interventional hour. To identify clinical, morphologic, and procedure-related parameters likely to predict the occurrence of post-interventional MES a logistic regression analysis was performed. Results: In 134 patients (111 male, mean age 69.7 years) relevant MES were detected in 51 patients (38 %) with a median of 4 MES/h and a maximum of 62 MES/h. Three factors were observed to be associated with increased post-interventional MES-counts. These included symptomatic lesion (p < 0.05), elevated total cholesterol (p < 0.05), and aspirin monotherapy (p < 0.0005). In a binary logistic regression model, dual antiplatelet therapy (OR 5.6, p < 0.0005) and asymptomatic lesions (OR 2.6, p < 0.05) were revealed as independent predictors for the absence of post-interventional MES. Conclusions: Post-interventional MES were most likely in symptomatic lesions and patients with elevated cholesterol. The absence of an effective dual antiplatelet therapy and symptomatic lesions were revealed as independent predictors for post-interventional MES. An effective pre-interventional dual antiplatelet and lipid lowering therapy might improve the safety of CAS.
The Effects of Romantic Love on Mentalizing Abilities
Authors: Wlodarski Rafael , Dunbar Robin I. M.
Published: December 2014

The effects of the human pair-bonded state of “romantic love” on cognitive function remain relatively unexplored. Theories on cognitive priming suggest that a state of love may activate love-relevant schemas, such as mentalizing about the beliefs of another individual, and may thus improve mentalizing abilities. On the other hand, recent functional MRI (fMRI) research on individuals who are in love suggests that several brain regions associated with mentalizing may be “deactivated” during the presentation of a love prime, potentially affecting mentalizing cognitions and behaviors. The current study aimed to investigate experimentally the effect of a love prime on a constituent aspect of mentalizing—the attribution of emotional states to others. Ninety-one participants who stated they were “deeply in love” with their romantic partner completed a cognitive task involving the assessment of emotional content of facial stimuli (the Reading the Mind in the Eyes task) immediately after the presentation of either a love prime or a neutral prime. Individuals were significantly better at interpreting the emotional states of others after a love prime than after a neutral prime, particularly males assessing negative emotional stimuli. These results suggest that presentation of a love stimulus can prime love-relevant networks and enhance subsequent performance on conceptually related mentalizing tasks.
Cluster-based comparison of the peptide mass fingerprint obtained by MALDI-TOF mass spectrometry. A case study: long-term stability of rituximab
Authors: Villacorta Pablo J. , Salmerón-García Antonio , Pelta David A. , Cabeza José , Lario Antonio , Navas Natalia
Published: December 2014

A cluster-based comparison algorithm applied to the MALDI-TOF-MS peptide mass fingerprint allows for tracking major changes in protein such as monoclonal antibodies.
On-surface formation of two-dimensional polymer via direct C–H activation of metal phthalocyanine
Authors: Sun Qiang , Zhang Chi , Cai Liangliang , Xie Lei , Tan Qinggang , Xu Wei
Published: December 2014

From high-resolution UHV-STM imaging and DFT calculations, we successfully obtained a 2D polymer structure formed through direct C–H activation followed by an aryl–aryl coupling of a metal-phthalocyanine (CoPc) on Ag(110).
Sharp variations in the electronic properties of graphene deposited on the h-BN layer
Authors: Kvashnin D. G. , Bellucci S. , Chernozatonskii L. A.
Published: December 2014

Investigation of the complex structure based on the graphene monolayer and the twisted BN monolayer was carried out.
Exceptional activity of sub-nm Pt clusters on CdS for photocatalytic hydrogen production: a combined experimental and first-principles study
Authors: Wu Qiyuan , Xiong Shangmin , Shen Peichuan , Zhao Shen , Li Yan , Su Dong , Orlov Alexander
Published: December 2014

Here we report the first ever observation of outstanding photocatalytic hydrogen production activity of sub-nm Pt cluster modified CdS nanocatalysts.
Unprecedented iminobenzosemiquinone and iminobenzoquinone coordinated mononuclear Cu(ii) complex formation under air
Authors: Mondal Manas Kumar , Biswas Abul Kalam , Ganguly Bishwajit , Mukherjee Chandan
Published: December 2014

LigandH4LS(AP/AP)comprised of two orthogonally placed non-innocent unit that were bridged by a common -orthoS atom. It reacted with CuCl2·2H2O and provided a mononuclear diamagnetic Cu(ii) complex where two non-innocent units were in two different oxidation states.
Antrodan, A β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia
Authors: Peng Chiung-Chi , Lin Yi-Ting , Chen Kuan-Chou , Chyau Charng-Cherng , Peng Robert Y.
Published: December 2014

Benign prostatic hyperplasia (BPH), one of the most common disease usually occurring in men in their 50s, has now become an atypical direct cause of mortality.
Selected dietary (poly)phenols inhibit periodontal pathogen growth and biofilm formation
Authors: Shahzad Muhammad , Millhouse Emma , Culshaw Shauna , Edwards Christine A. , Ramage Gordon , Combet Emilie
Published: December 2014

Periodontitis (PD) is a chronic infectious disease mediated by bacteria in the oral cavity.
Aerobic oxidation of 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid in water under mild conditions
Authors: Liu Bing , Ren Yongshen , Zhang Zehui
Published: December 2014

Pd/C@Fe3O4 catalyst showed high catalytic activity in the oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid under mild reaction conditions.
Synthesis of a novel water-soluble cylindrical macrotricyclic host and its complexation with N-methylquinolinium and N-methylisoquinolinium salts: formation of 1 : 2 complexes in water
Authors: Zeng Fei , Chen Chuan-Feng
Published: December 2014

A water-soluble cylindrical macrotricyclic host could form 1 : 2 complexes with N-methylquinolinium or N-methylisoquinolinium salts in water solution and in the solid state.
Hierarchical nanoarray materials for advanced nickel–zinc batteries
Authors: Lu Zhiyi , Wu Xiaochao , Lei Xiaodong , Li Yaping , Sun Xiaoming
Published: December 2014

Due to the unique structural advantages, hierarchical Co3O4@NiO nanoarrays can be regarded as advanced electrodes for Ni–Zn batteries.
A simple and sensitive graphene oxide/gold nanoparticle surface plasmon resonance Rayleigh scattering-energy transfer analytical platform for detection of iodide and H2O2
Authors: Wang Yaohui , Zhang Xinghui , Liu Qingye , Wen Guiqing , Liang Aihui , Jiang Zhiliang
Published: December 2014

A sensitive graphene oxide/nanogold surface plasmon resonance Rayleigh scattering-energy transfer analytical platform was developed for detection of iodide and H2O2.
Application of soy protein coatings and their effect on the quality and shelf-life stability of beef patties
Authors: Guerrero Pedro , O'Sullivan Maurice G. , Kerry Joe P. , de la Caba Koro
Published: December 2014

There was no significant change in lipid oxidation up to day 10 of storage for soy-protein-coated samples.
Extended isoindigo core: synthesis and applications as solution-processable n-OFET materials in ambient conditions
Authors: Xu Shiliang , Ai Na , Zheng Jie , Zhao Na , Lan Zhenggang , Wen Lirong , Wang Xiao , Pei Jian , Wan Xiaobo
Published: December 2014

Two isoindigo derivatives fused with benzothiophene (C20-DBTII) and benzofuran (C20-DBFII) heterocycles have been synthesized.
Structural conservation of the short α-helix in modified higher and lower polarity water solutions
Authors: Shen Hao , Cheng Wei , Zhang Feng-Shou
Published: December 2014

Which conformation is preferred when the polarity of water molecules is scaled byEP=ELJ+S2EC?
Seed-induced synthesis of hierarchical ZSM-5 nanosheets in the presence of hexadecyl trimethyl ammonium bromide
Authors: Liu Min , Li Junhui , Jia Wenzhi , Qin Mengjiao , Wang Yanan , Tong Kai , Chen Huanhui , Zhu Zhirong
Published: December 2014

Hierarchical ZSM-5 nanosheets with honeycomb morphology were synthesized by seed-inducing in the presence of hexadecyl trimethyl ammonium bromide as template.
Recycling gold and copper from waste printed circuit boards using chlorination process
Authors: He Yuchen , Xu Zhenming
Published: December 2014

This study provides a less-polluted and more efficient process for selective recovery of gold and copper from waste PCBs through pretreatment processes.
Ionothermal synthesis of black Ti3+-doped single-crystal TiO2 as an active photocatalyst for pollutant degradation and H2 generation
Authors: Li Guisheng , Lian Zichao , Li Xin , Xu Yuanyuan , Wang Wenchao , Zhang Dieqing , Tian Fenghui , Li Hexing
Published: December 2014

Black Ti3+/TiO2 single-crystals synthesized via an ionothermal process exhibited high activity for the photocatalytic degradation of pollutants and hydrogen evolution reaction.
Electrophoretic deposition improves catalytic performance of Co3O4nanoparticles for oxygen reduction/oxygen evolution reactions
Authors: Fayette M. , Nelson A. , Robinson R. D.
Published: December 2014

Electrophoretic deposition was found to improve the activity of cobalt oxide nanoparticulate thin films for oxygen reduction/evolution in spite of an apparent decrease in active surface area.
Synthesis of Ni(OH)2/RGO pseudocomposite on nickel foam for supercapacitors with superior performance
Authors: Min Shudi , Zhao Chongjun , Zhang Zhuomin , Chen Guorong , Qian Xiuzhen , Guo Zaiping
Published: December 2014

A “pseudocomposite” with unique nano-architecture of two Ni(OH)2/RGO layer was in situ synthesized on nickel foam (NF) using a facile onepot hydrothermal approach, which exhibits superior capacitive performance (15.65 F cm−2 at 7 mA cm−2, 90.6% capacity retention after 5000 cycles at 20 mA cm−2).
Highly efficient, little efficiency roll-off orange-red electrophosphorescent devices based on a bipolar iridium complex
Authors: Li Guomeng , Feng Yansong , Peng Tai , Ye Kaiqi , Liu Yu , Wang Yue
Published: December 2014

A novel bipolar phosphor BZQPG realizes a series of highly efficient orange-red PhOLEDs with the wide-range doping concentrations of 15, 20 and 25 wt%. They exhibit stable CIEx,y (0.57 ± 0.01, 0.41 ± 0.01) and constantly high peak PE and EQE values of >60 lm W−1 and 22%, respectively.
Epidermal growth factor receptor inhibitor protects against abdominal aortic aneurysm in a mouse model
Authors: Obama Takashi , Tsuji Toshiyuki , Kobayashi Tomonori , Fukuda Yamato , Takayanagi Takehiko , Taro Yoshinori , Kawai Tatsuo , Forrester Steven J. , Elliott Katherine J. , Choi Eric , Daugherty Alan , Rizzo Victor , Eguchi Satoru
Published: December 2014

Inhibition of epidermal growth factor receptor (EGFR) activation protected mice from abdominal aortic aneurysm (AAA), which is probably due to suppression of vascular endoplasmic reticulum (ER) stress. Since the signal was confirmed in humans, EGFR may provide a novel therapeutic target for aortic aneurysm.