bluuebunny/crossref_metadata_2025 huggingface dataset:
MA’HAD AL-JAMIAH DI INSTITUT AGAMA ISLAM NEGERI AMBON
Authors: Jumaeda St
Published: April 2024

Tujuan dari penelitian ini adalah untuk memperoleh informasi
yang objektif tentang eksistensi ma’had al-jamiah IAIN Ambon dalam
pembinaan Mahasiswa. Penelitian ini adalah suatu pendekatan kualitatif
(qualitative methode) untuk mendeskripsikan dan menganalisis fonemena,
peristiwa, aktivitas sosial, sikap, kepercayaan, persepsi, pemikiran orang
secara individual maupun kelompok dengan beberapa deskripsi
digunakan untuk menemukan prinsip-prinsip dan penjelesan yang
mengarah pada penyimpulan. Temuan dalam penelitian ini bahwa
keberadaan ma’had al-jamiah IAIN Ambon sebagai wahana pembinaan
mahasantri dalam bidang pengembangan ilmu keagamaan dan
kebahasaan, peningkatan penanaman dan pelestarian tradisi spiritualitas
keagamaan, untuk melahirkan mahasiswa yang berkualitas mumpuni di
bidang ilmu agama islam, memiliki keunggulan akademik dan integritas
moral yang luhur, dalam memberikan sumbangan yang berarti bagi
pengembangan dan penerapan ilmu agama, teknologi, dan kebudayaan
islam.
POLA PENDIDIKAN KARAKTER DALAM MEMBENTUK KARAKTER MAHASISWA DI FITK JURUSAN PENDIDIKAN AGAMA ISLAM IAIN AMBON
Authors: Laganti Salayar
Published: April 2024

Penelitian ini bertujuan untuk mengetahui karakter mahasiswa
dan pola pendidikan dalam membentuk karakter mahasiswa di FITK
Jurusan Pendidikan Agama Islam IAIN Ambon. Pendekatan yang
digunakan dalam penelitian ini yakni pendekatan kualitatif, Lokasi
penelitian di FITK Jurusan Pendidikan Agama Islam IAIN Ambon. Dengan
teknik pengambilan data yaikni observasi, dokumentasi, dan wawancara
dengan Ketua Jurusan Pendidikan Agama Islam, Dosen serta para
pegawai dan Staf. Temuan dalam penelitian menunjukkan bahwa karakter
mahasiswa PAI yang cenderung memiliki perilaku yang buruk yakni
mahasiswa yang nilai-nilainya tidak tuntas sehingga cenderung
melakukan aksi demonstrasi dan lainya, perilaku buruk tersebut
dikarenakan belum optimalnya pola yang dikembangkan oleh jurusan
Pendidikan Agama Islam, sedangkan pada mahasiswa yang memiliki
kepribadian atau karakter yang baik yakni mahasiswa yang aktif dalam
kegiatan-kegiatan kemahasiswaan baik di dalam kampus maupun diluar.
Adapun pola pendidikan karakter mahasiswa di FITK Jurusan Pendidikan
Agama Islam yakni, 1) pembinaan karakter dalam proses pembelajaran di
kelas, 2) pembinaan melalui Workshop, 3) pembinaan melalui UKM, 4)
Pembinaan melalui dosen Penasehat Akademik. Dengan harapan kiranya
melalui pola pendidikan karakter tersebut sebagai solusi guna membentuk
karakter mahasiswa.
PENDIDIKAN ANAK MENURUT SURAT LUQMAN AYAT 12-19 DALAM TAFSIR IBNU KATSIR
Authors: Hayati Nufus Rohani
Published: April 2024

Penelitian ini bertujuan untuk membuktikan bahwa
pendidikan anak merupakan tanggungjawab mutlak orangtua, karena
anak adalah amanah yang diberikan Allah. Oleh karena itu wajib
diperhatikan melalui pendidikan dan bimbingan yang intensif dari orangtua
untuk anak. serta menganalisa aspek-aspek pendidikan yang terdapat
dalama al-Quran surat Luqman ayat 12-19. Penelitian ini berjenis
penelitian pustaka (library research) dengan menggunakan analisis isi
(content analysis) untuk menemukan penjelasan secara rinci tentang ayat
12-19 surat Lukman. Hasil penelitian membuktikan terdapat 3 aspek
pendidikan yang dapat menjadi pedoman dan acuan para orangtua dalam
mendidik anak, yaitu, pertama pendidikan Tauhid, kedua, pendidikan
Syari’at dan ketiga, pendidikan Akhlak, dari ketiga aspek pendidikan
tersebut diharapkan anak memahami tanggungjawab dan kewajibannya
sebagai anak yang beribadah kepada Allah dan berbakti kepada orangtua.
PENDIDIKAN ISLAM SEBAGAI BASIS PENDIDIKAN KARAKTER (Studi Terhadap Perilaku Mahasiswa Multi Etnis IAIN Ambon)
Authors: Kaliky Mokhsin
Published: April 2024

Identitassuku, budaya, dan bahasa tidak dijadikan sebagai instrumen persatuan
ke berbagai bangsa, malah sebagai alasan untuk saling bermusuhan, kesadaran
multikulturalisme pada level mahasiswa belum tampak pada pemikirannya. Kampus
yang seharusnya merupakan ruang diskusi ide dan gagasan berubaH menjadi ajang
permusuhan. Sehingga Hasil penelitian ini menunjukan bahwa perilaku mahasiswa
multi etnis IAIN Ambon kurang menanamkan perilaku menghargai dan menghormati,
toleransi, serta gotong royong masih jauh dari yang dicita-citakan, sehingga prasangka
diantara mahasiswa masih sering ditunjukkan dalam aktifitas kesehariannya di kampus.
Pola hubungan mahasiswa multi etnis di IAIN Ambon masih terpasung hanya pada
kelompok masing-masing, sehingga pola hubungan antar mahasiswa kurang
menanamkan sikap tolong menolong dengan baik serta kurang menajalin talisilaturahim
dengan mahasiswa multi etnis. Implikasi pendidikan Islam terhadap pembentukan
karakter mahasiswa di IAIN Ambon kurang menyentuh terhadap mahasiswa
keseluruhan, hampir seluruh pendidikan yang diterapkan di kampus hanya sebatas
pengetahuan kognitif atau At-Ta’lim, semata implikasinya mahasiswa tidak manjaga
hubungan dengan baik, sering mengabaikan etika dan moral, kurangnya menerapkan
hubungan hidup bersama, dan kurangnya kesadaran tentang pentingnya hubungan
sesama mahasiswa multi etnis tersebut
Implementasi Metode Talqin Dalam Pembelajaran Tahfizhul Qur’an Di Sekolah Dasar Al Hanief Kota Bekasi
Authors: Salafudin Salafudin , Darwis Darwis
Published: April 2024

This study contains an analysis of the preparation for the implementation of talqin in learning tahfizhul Qur'an at AL HANIEF Elementary School; the form of implementation of the talqin method in learning tahfizhul Qur'an; and analysis of the factors supporting and inhibiting the implementation of talqin. The approach used is qualitative with descriptive analysis method. Data collection techniques were carried out by: interviews, observation and documentation. The data analysis process is carried out through collecting, sorting, and checking the validity of the data. The results of this study indicate that: At Sekolah Dasar AL HANIEF Rawalumbu, Bekasi City has implemented the tahfizhul Qur'an program by implementing the talqin method in the learning process. The process starts from planning, then implementing talqin with certain shapes and patterns so that a verse can be memorized. As a result, 90% of AL HANIEF Elementary School students can reach the target of memorizing Juz 30 when they graduate from this school, even if only by allocating 2 hours of lessons (30 minutes X 2), or just 1 hour a week. There are factors that support and hinder the implementation of this talqin. Supporting factors: School readiness in carrying out the tahfizhul Qur'an program; the role and competence of the tahfizh teacher; enthusiastic students; the activeness and creativity of the tahfizh teacher; conducive school environment; parental support; and control and evaluation. While the inhibiting factors: loosening student enthusiasm; Diversity of student backgrounds; limited control and supervision of students outside of school; and the lack of time to learn tahfizhul Qur'an in schools and the limited availability of tahfizh teachers with this talqin method. The results of this study indicate that the talqin method is an effective approach in learning tahfizhul Qur'an in schools, as has been implemented in Sekolah Dasar AL HANIEF. If this method is implemented better, the results will be even better
Implementasi Kegiatan Muhadhoroh Dalam Meningkatkan Kecerdasan Linguistik Santri Pondok Pesantren At-Taqwa
Authors: Muidal Ahmad , Rizki Gunawan Hasibuan Akmal , Siddiq Abdurrahman
Published: April 2024

This study examines two problems, namely the implementation of muhadhoroh activities in improving the linguistic intelligence of students and efforts to improve linguistic intelligence in muhadhoroh activities. This study aims to determine the results of the implementation of muhadhoroh activities in improving the linguistic intelligence of students at Pondok Pesantren At-Taqwa Bekasi. Data obtained through observation, interviews and documentation. Data analysis in this study is a qualitative descriptive analysis technique, namely, data analysis methods in the form of words, pictures, and not numbers. The results showed that linguistic intelligence is generally influenced by the environment and the individual. In particular, language is influenced by (a) the ability to master intonation and tempo. (b) the ability to compose speech texts. (c) the ability to harmonize language using standard and non-standard words. Efforts that can be made to improve the linguistic intelligence of students are carried out by practicing regularly and seriously. Efforts to overcome linguistic problems, namely by presenting groups of students who are proficient in speech with the aim of motivating other students to foster a desire to improve the linguistic abilities of students in muhadhoroh, while Asatidz as a supervisor who provides direct guidance and evaluation to students at the end of each muhadhoroh activity.
Pengaruh Evaluasi Proses Pembelajaran Terhadap Hasil Belajar Mata Pelajaran Pendidikan Agama Islam Di SMA Muhajirin
Authors: Awaliya Hilyatun , Fitriani Mustika , Firmansyah Nanda
Published: April 2024

This study aims to determine the effect of evaluation on the learning process on student learning outcomes in PAI subjects in class X (Ten) SMA Muhajirin Bekasi. Evaluation is very important in the world of education because evaluation is a process in which a value judgment or decision is made from various observations, backgrounds and training of the evaluator. With the evaluation in the learning process educators can find out students' understanding of the material that has been taught so that they have achieved the goals that have been set. This research is a quantitative study using descriptive statistical data analysis, which aims to find out how student learning outcomes are in PAI subjects in class X (ten) SMA Muhajirin Bekasi. The method used in this study is using correlation analysis, which aims to determine whether or not there is a relationship between variables so that it can make it easier to determine and predict the values of other variables. The population in this study totaled 37 students from all classes XA and XB, and the sample used in this study was class XA and XB SMA Muhajirin Bekasi, totaling 20 students from class XA and class XB, totaling 17 students. With a total of 37 samples. Sampling using random sampling technique, namely by taking random samples in class XA and XB. After being analyzed, it turns out that based on the SPSS calculation results, two sample T-tests get a coefficient value of 0.422, which means a coefficient value of 0.4 to <0.6 = in the category of having a relationship between variables that is quite large or strong enough. then there is a significant influence between the evaluation of the learning process with learning outcomes. So there is an influence of the evaluation of the learning process on the results of PAI learning at SMA Muhajirin Bekasi. Evaluating the learning process that has been implemented.
Peran Lembaga Dakwah Kampus Dalam Membina Akhlak Pada Mahasiswa Universitas Islam 45
Authors: Mulyani Sri , Ayu Rohayah Aulia
Published: April 2024

The purpose of this research is to determine the concept of morals and efforts to develop student morals at the Islamic University 45 Bekasi. This thesis was prepared based on field data using qualitative methods. The data collected was obtained through observation, in-depth interviews and documentation studies, while the analysis used qualitative descriptive analysis techniques, namely descriptions and descriptions of the collected data as a whole about an actual situation. The results of this research show that the campus da'wah institution at the Islamic University "45" Bekasi has a moral concept and makes efforts to develop and direct it. The concept of improving morals and efforts to improve them are closely related. In the concept of improving morals, LDK has 4 organized orders, namely (1) Preparing and improving individual abilities to do good deeds, (2) Preparing and improving participants' skills to do good deeds at the level of the da'wah movement , (3) Prepare and improve participants' skills to do charity at the community level, (4) Prepare and improve participants' skills to do charity and interact with non-Muslims. In line with the efforts that have been established by LDK in the form of a work program which includes three aspects, namely the spiritual/spiritual aspect, the fikriyah/intellectual aspect, and the physical/physical aspect (body resilience) as well as the muamalah/relationship aspect with fellow humans. Organizationally, LDK tends to be open (inclusive) but as a movement it tends to be exclusive. This is because it can be seen from several things, namely the distinctive appearance identity of LDK cadres (wide headscarves, Palestinian flags, not shaking hands with the opposite sex) and then the use of the hijab (barrier) in activities to provide distance in interacting with students outside UKM LDK.
Pengaruh Perubahan Kurikulum 2013 Terhadap Motivasi Belajar Siswa Pada Mata Pelajaran Pendidikan Agama Islam
Authors: Anisa Nur , Adelin Nur , Istaqomaly M. Fikri , Darwis Darwis
Published: April 2024

This study aims to determine the policies and changes to Curriculum 13 for students, as well as educators' efforts to increase students' learning motivation in Islamic Religious Education subject class X IPS at SMAN 4 Bekasi. From the results of the study with a total sample of 15 people, it was obtained that the students' perceptions about the 2013 curriculum at SMAN 4 Bekasi had a positive phenomenon, as evidenced by the maximum sample value that obtained the lowest score of 30 with the highest score of 50, the sum score of 593, the total score the average (mean) is 39.53, and the standard deviation score is 6.632 (2) The learning motivation of students at SMAN 4 Bekasi has a positive phenomenon, as evidenced by the maximum sample value which obtained the lowest score of 28 with the highest score of 50, the sum score is 628, the average score (mean) is 41.87, and the standard deviation score is 6.770, (3) From the results of the moment product correlation test the relationship between students' perceptions of the 2013 curriculum and students' learning motivation is worth 0.799, which means that the coefficient value is 0.7 <0.9 = in the category of having a lower or weaker relationship between variables. Thus the results of the Summary Model are used to determine the relationship between two or more variables in the regression equation. Here what is seen is the R-Square value. The R-Square value in these results means that the effect of the 2013 Curriculum (X1) on Learning Motivation (Y) is 63.8%, the remaining 36.2% is influenced by other variables outside the model. The terms of the relationship between variables are good or not if the R-Square value is above 50% it means good, if it is below 50% it means it is badin evaluating the learning process that has been implemented.
THE MEMOIRS OF ERAST NUDATOV AS A SOURCE OF SHEVCHENKO’S BIOGRAPHY OF RAIM PERIOD (1848—1849)
Authors: Boron Oleksandr
Published: April 2024

The paper aims to evaluate the reliability of Erast Nudatov’s memoirs who was an ensign of the fourth linear battalion of the Separate Orenburg Corps at the time of his acquaintance with Shevchenko. The memoirs were recorded by the Russian journalist and writer Dmitry Klemensov, whose real surname was Montvid. Due to the lack of other sources for reconstructing the conditions of the Aral Sea Expedition’s stay in Raim in 1848—1849, D. Klemensov’s publication repeatedly attracted close attention from researchers. However, many of them have been overly credulous toward the information it contains. Some of Klemensov’s assumptions had no factual basis and led to the spread of several legends in Shevchenko studies, primarily concerning references to Shevchenko’s artistic works (now unknown). Shevchenko did not draw any political caricatures, let alone “obscene pictures.” It seems that due to the limited memories of E. Nudatov, D. Klemensov had to largely speculate on a number of episodes, depicting Shevchenko as involved in various incidents occuring in the Raim fortress or those heard by the ensign during his service.
The information provided by E. Nudatov has been cross-checked with documents, reliable memoirs, etc. The journalist’s treatment of his story turned out to be too fictionalized, not least because of the publisher’s financial interest. It is indicative that the editorial board of the “Kiievskaia Starina” journal, known for its commitment to preserving the poet’s memory, did not publish the proposed material. Perhaps this was due to doubts about its authenticity or disagreement about the terms of publication.
In conclusion, it is advisable to only use an information from D. Klemensov’s material, confirmed by other sources. The rest of the stories, in particular those about Shevchenko’s antics, which are definitely too many for the three months of the exile’s and the ensign’s joint stay in Raim, should be used with great caution, bearing in mind the low reliability of these memoirs.
Mykhail Semenko as a Futurist and ‘Borotbist’
Authors: Omelchuk Olesia
Published: April 2024

Mykhail Semenko as a Futurist and ‘Borotbist’
Silent Luxury or Revenge Consumption? Reimagining the World of Luxury and Consumer Purchase Intentions Post-Covid 19
Authors: Khan* Talalah , Chapa Sindy
Published: April 2024

COVID-19 not only sent a health shockwave to the world but also disrupted global economies. Major shifts in luxury consumer behavior emerged as a result of the pandemic. This study aims to empirically investigate luxury purchase patterns in a post-COVID-19 world for different cultural, ethnic, and gender segments. It employs a quantitative survey with a sample of 262 participants to examine whether consumers prefer revenge or silent luxury, in-store or online channels. Results exhibit that high power distance and more masculine consumers favor revenge luxury while low power distance and more feminine ones prefer silent luxury consumption. Females and non-binary genders also exhibit higher purchase intentions for silent, more sustainable luxury consumption than males. Collectivistic, African American consumers are more inclined towards in-store luxury channels than their Non-Hispanic White counterparts. The study findings have several pertinent corporate and managerial implications as the US$1.52 trillion world of luxury is reimagined post-COVID-19.
Balancing Language and Content: A Study of Negotiation Learning in Applied English Courses
Authors: Chang, Ph.D. Chi-yu
Published: April 2024

This study examines the impact of subject content versus the English language on students whose first language is non-English. Focusing on Applied English juniors and above, the course in question required negotiation learning through English. Surprisingly, students often reverted to their native language (Mandarin Chinese) during scenario discussions and role-play, despite the assumption that English should be exclusively used. The semester-end survey, based on a 5-point Likert scale, revealed several key findings as follows. First, the course facilitated diverse problem-solving approaches. Secondly, negotiation skills were effectively put into practice. Thirdly, role-play activities played a critical role. Fourthly, teacher-delivered lectures enhanced content understanding. Interestingly, when asked about continuous English usage, approval significantly dropped when foreign students were present. These results suggest that prioritizing knowledge acquisition, skill internalization, and higher-order abilities is essential, even if the “whole English” pattern is not strictly enforced during class.
Investigation of Water-Soluble Preservatives in Frequently Used Energy-Stimulating Herbal Drugs in Rajshahi City, Bangladesh
Authors: Ar-Rashid Mamun , Islam Nazmul , Ahmad Hasan , Zakaria Choudhury M. , Banu Laila Arjuman , Islam Nurul , Zamir Rausan
Published: April 2024

The prevalence of erectile dysfunction is on the rise. Patients are turning to herbal drugs as an alternative to allopathic therapy or are drawn towards natural alternatives. However, there are concerns about the safety of these medications. An effort was made to determine the level of two commonly used water-soluble preservatives, sodium benzoate and potassium sorbate in 54 finished energy-stimulating herbal preparations. Maceration-assisted UV- Vis spectrometry was adopted for determining the analytes in bulk and finished formulations. Concern about harmful effects on human health has been raised after 5% of samples were found to be risky for oral ingestion of sodium benzoate. If ingested exceeding the prescribed daily dose, the high concentration of potassium sorbate in some formulations raises concerns regarding daily consumption. To assess the preservative levels in herbal medicines, more laboratory-based studies are required.
Transformasi Teratoma Matur Mediastinum Menjadi Mucinous Adenocarcinoma Disertai Sitologi Sikatan Bronkus Positif
Authors: Liana Nana , Yenita Yenita
Published: April 2024

Pendahuluan: Teratoma matur adalah germ cell tumor yang paling banyak ditemukan di mediastinum yaitu 50-70%. Namun kejadian transformasi keganasan non germ cell masih sangat jarang hanya sekitar 6% dari germ cell tumor. Laporan Kasus: Kami melaporkan kasus pasien perempuan usia 43 tahun datang dengan keluhan sesak nafas dan massa kistik multilokular di mediastinum anterior. Pasien menjalani tindakan torakotomi eksplorasi dan eksisi tumor dengan diagnosis histopatologi teratoma matur. Sepuluh bulan setelah operasi pasien datang dengan benjolan baru di suprasternum. Biopsi massa di suprasternum menunjukkan metastasis mucinous carcinoma. Pemeriksaan CT-Scan toraks tampak adanya pulmoner metastase dari tumor mediastinum anterior (residif). Pada sitologi sikatan bronkus juga ditemukan metastase mucinous adenocarcinoma. Setelah dilakukan review pada sediaan awal ditemukan fokus mucinous adenocarcinoma dalam teratoma matur mediastinum dan radang granulomatosa ekstensif yang menandakan ruptur kista. Kesimpulan: Teratoma matur dapat mengalami transformasi keganasan dari komponen non germ cell. Untuk mengetahui asal komponen mucinous adenocarcinoma dibutuhkan pemeriksaan imunohistokimia CK7, CK20 dan TTF1. Pada kasus ini didapatkan CK7 positif, CK 20 negatif dan TTF1 negatif, sehingga disimpulkan komponen mucinous adenocarcinoma berasal dari teratoma matur di mediastinum yang mengalami transformasi keganasan
Pengaruh Video Animasi terhadap Perilaku Pencegahan COVID-19 pada Anak Sekolah Dasar
Authors: Yanti Farah Sevnell , Hanum Fathiya Juwita , Firdawati Firdawati , Rahmadian Rizki , Amir Arni , Nurhajjah Siti
Published: April 2024

Pendahuluan: Coronavirus Disease (COVID-19) merupakan penyakit infeksi virus SARS-CoV-2 yang menyerang sistem pernapasan manusia. Penyakit ini memiliki tingkat penularan yang tinggi sehingga diperlukan upaya pencegahan untuk menghambat penularannya. Anak sekolah dasar termasuk kelompok yang berisiko menjadi carrier dan menularkan virus ini kepada orang lain meskipun tidak bergejala. Promosi kesehatan pada kelompok ini penting dilakukan melalui media penyampaian informasi yang menarik agar mereka menyadari pentingnya melakukan upaya pencegahan penyakit COVID-19. Tujuan penelitian: Untuk melihat pengaruh video animasi tentang pencegahan COVID-19 terhadap pengetahuan, sikap, dan tindakan siswa sekolah dasar kelas 3-5 SDN 10 Lambung Bukit Padang. Metode: Ini adalah penelitian analitik menggunakan pre experimental design dengan one-group pretest-posttest design. Terdapat sebanyak 52 sampel siswa SDN 10 Lambung Bukit Padang. Data diambil menggunakan kuesioner dan dianalisis dengan uji wilcoxon signed rank test. Hasil: Sebelum dilakukan intervensi mayoritas sampel memiliki tingkat pengetahuan yang kurang (48,1%), sikap yang baik (61,5%) dan tindakan yang baik (75,0%). Setelah diberikan intervensi, mayoritas memiliki tingkat pengetahuan yang cukup (57,7%), sikap yang baik (84,6%) dan tindakan yang baik (84,6%). Hasil analisis bivariat pre dan post intervensi menggunakan Uji Wilcoxon mendapatkan nilai p-value < 0,05 untuk variabel pengetahuan, sikap, dan tindakan. Hal ini menunjukkan setelah dilakukan intervensi terdapat perubahan yang bermakna (signifikan) dari  pengetahuan, sikap, dan tindakan responden tentang pencegahan COVID-19. Kesimpulan: Terdapat pengaruh video animasi tentang pencegahan COVID-19 terhadap pengetahuan, sikap, dan tindakan siswa sekolah dasar kelas 3-5 SDN 10 Lambung Bukit.
Berbagai Tanaman di Indonesia untuk Tabir Surya
Authors: Nazifah Fauzana , Yenny Satya Widya
Published: April 2024

Indonesia adalah salah satu negara dengan paparan sinar matahari yang tinggi dan sebagian besar penduduknya bekerja diluar ruangan sehingga memerlukan suatu perlindungan kulit. Sinar matahari selain memberi manfaat juga mempunyai dampak buruk pada kulit jika terpapar secara berlebihan. Sinar ultraviolet UVB dan UVA bekerja secara sinergis merusak kulit sehingga dibutuhkan pencegahan atau perlindungan untuk mengurangi dampak buruk pada kulit akibat radiasi tersebut.  Jika paparan sinar matahari berlebihan, jaringan epidermis kulit tidak mampu sepenuhnya melawan efek negatif sehingga diperlukan perlindungan, salah satunya dengan tabir surya. Tabir surya merupakan pelindung kulit dari paparan sinar matahari karena ikatan yang saling berkonjugasi sehingga ikatan tersebut beresonansi saat terpapar sinar UV dan akan menurunkan energi untuk melindungi kulit. Tabir surya memiliki dua mekanisme kerja yaitu secara fisik dengan memantulkan dan membiaskan sinar UV yang mengenai kulit dan secara kimia dengan cara menyerap sinar UV yang dipancarkan oleh matahari. Pada daun tumbuhan terdapat zat alami yang dapat diekstrak dan dapat bertindak sebagai sumber potensial tabir surya karena bersifat fotoprotektif. Daun-daunan seperti daun kersen, daun cempedak dan daun binahong mempunyai kemampuan untuk melindungi kulit melalui senyawa yang terkandung di dalam tanaman yang berupa senyawa bioaktif seperti senyawa fenolik dan didukung oleh adanya senyawa yang bersifat antioksidan.
Carcinoma Endometrioid Ovary pada Struma Ovarii
Authors: Muhammad Syamel , Antonius Puja Agung , Meuthia Susan , Savannah Aisha
Published: April 2024

Kanker ovarium merupakan penyebab utama kematian pada wanita yang didiagnosis sebagai kanker ginekologi. Tingginya angka kematian akibat kanker ovarium karena mayoritas kasus bersifat asimptomatik dan skrining yang dilakukan untuk menegakkan diagnosis masih kurang. Hal ini menyebabkan kanker ovarium dikenal sebagai silent killer. Etiologi spesifik kanker ovarium hingga belum diketahui dengan pasti, namun teradapat beberapa faktor risiko yang berperan terhadap terjadinya kanker ovarium. Faktor risiko genetik diduga berkaitan erat dengan kejadian kanker ovarium, diantaranya mutasi pada gen TP53, BRCA1 dan BRCA2.  Diagnosis kanker ovarium sulit dilakukan pada stadium dini karena tidak adanya gejala spesifik.  Untuk menegakkan diagnosis kanker ovarium dibutuhkan anamnesis, pemeriksaan fisik dan pemeriksaan penunjang seperti CT scan, USG, pemeriksaan tumor marker dan biopsi. Hingga saat ini, pembedahan masih menjadi penatalaksanaan utama bagi kanker ovarium. Pemeriksaan histopatologi juga perlu dilakukan untuk menentukan keganasan, jenis kanker, dan penentuan staging. Kemoterapi adjuvan diberikan pada pasien setelah pembedahan, kecuali jika penyakit hanya terbatas pada ovarium dan  pada kanker yang tidak bisa dioperasi. Prognosis kanker ovarium bergantung dari jenis kanker, stadium  dan komplikasi yang terjadi. Pada jurnal ini dilaporkan kasus seorang pasien perempuan, berusia 59 tahun dengan carcinoma endometrioid ovary pada struma ovarii.
Hubungan Nilai Gleason Score dan Grade Groups dengan Ekspresi Fibroblast Activation Protein di Stroma Tumor pada Adenokarsinoma Prostat
Authors: Hardian Sonny , Yenita Yenita , Mulyani Henny , Asri Aswiyanti , MYH Etriyel , Yetti Husna
Published: April 2024

Latar Belakang: Gleason score dan grade groups (GrGp) digunakan sebagai nilai prognostik adenokarsinoma prostat. Namun, lingkungan mikro tumor yang didominasi oleh cancer – associated fibroblast (CAF) juga memiliki peranan dalam progresivitas perkembangan kanker dan kejadian metastasis. Terdapat heterogenitas CAF berdasarkan sel asalnya, dan 90% dari CAF bisa dideteksi menggunakan biomarka fibroblast activation protein (FAP). Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan nilai Gleason score dan GrGp dengan ekspresi FAP sebagai biomarka CAF di stroma tumor pada adenokarsinoma prostat. Metode: Penelitian ini adalah penelitian observasional dengan pendekatan cross sectional study. Dilakukan review slide HE dan pulasan IHK dengan antibodi anti-FAP pada 33 sampel blok parafin adenokarsinoma prostat yang berasal dari prostatektomi atau TURP. Hasil pulasan IHK dinilai menggunakan imunnoreactive score (IRS) dengan hasil positif dan negatif. Gleason score dan GrGp dikelompokkan menjadi low grade dan high grade. Analisis data dilakukan dengan Chi-square test dan nilai p <0,05 dianggap bermakna secara stastistik. Hasil: Ekspresi FAP positif ditemukan pada 18 kasus (54,5%) dari 33 sampel yang diperiksa, dengan rincian 50% kasus dikelompok low grade Gleason score dan 54,8% pada high grade Gleason score (p = 1.000). Pada kelompok low GrGp ditemukan 33,3% dan 59,3% pada high GrGp (p = 0,375). Secara statistik tidak didapatkan hubungan bermakna antara nilai Gleason score dan GrGp dengan ekspresi FAP di stroma tumor adenokarsinoma prostat. Kesimpulan: Penelitian ini mendapatkan ekspresi FAP positif dan negatif pada setiap kelompok Gleason score dan GrGp. Hal ini mungkin disebabkan karena adanya heterogenitas dari CAF. Diperlukan penelitian lebih lanjut untuk menilai heterogenitas dari CAF yang berperan dalam adenokarsinoma prostat untuk menggali potensi faktor prognostik dan strategi terapi di masa depan.
Tingkat Pengetahuan Radiografer Di Rumah Sakit Kota Padang Tentang Radiasi Dan Proteksi Radiasi
Authors: Firdaus Friskha Suhailah , Septiana Vina Tri , Febrianto Budi Yulhasfi
Published: April 2024

Latar Belakang: Radiografer merupakan tenaga kesehatan yang memiliki tugas, wewenang dan tanggung jawab untuk melakukan kegiatan radiografi dan pencitraan di unit pelayanan kesehatan. Oleh karena itu, petugas radiografer harus memiliki pengetahuan yang baik mengenai radiasi dan proteksi radiasi dengan baik dan benar. Tujuan: Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan radiografer di rumah sakit Kota Padang tentang radiasi dan proteksi radiasi. Metode: Penelitian ini dilakukan di RSI Siti Rahmah, RS Universitas Andalas, dan RSU Aisyiyah dengan menggunakan kuesioner dan mengelompokkan tingkat pengetahuan radiografer tersebut dengan jumlah sampel 29 orang. Hasil: Tingkat pengetahuan radiografer tentang radiasi dan proteksi radiasi adalah cukup (72,4%). Serta, mayoritas responden berjenis kelamin wanita (37,9%) dengan rentang umur 26-35 tahun (58,6%) dan pendidikan terakhirnya diploma 3 (65,5%) dengan masa bekerjanya kurang dari 5 tahun (41,4%) memiliki pengetahuan yang cukup mengenai radiasi dan proteksi radiasi. Kesimpulan: Tingkat pengetahuan radiografer di rumah sakit Kota Padang tentang radiasi dan proteksi radiasi adalah cukup dengan mayoritas respondennya berjenis kelamin wanita, usia 26-35 tahun, lulusan diploma 3, serta telah bekerjanya selama kurang dari 5 tahun.
A performance decolonial de Rachel Reis no álbum Meu Esquema e a cena musical afrolatina de Salvador
Authors: Gumes Nadja Vladi , Rodrigues Lima Tatiana
Published: April 2024

Neste artigo trazemos os primeiros resultados de uma investigação que busca pensar as práticas musicais ambientadas em territorialidades decoloniais, a partir de uma perspectiva interseccional. Tendo como assunto de pesquisa o álbum visual Meu Esquema, de Rachel Reis, propomos a articulação da noção de cena musical a partir da conexão com conceitos como Performance, Amefricanidade, Feminismo Decolonial e Ancestralidade, para compreender fenômenos culturais urbanos ancorados em performances de gênero, pós-gênero, raça/etnia, sexualidades, cidadania, classe, que se materializam em cidades da América Latina. Com este objetivo, propomos o conceito de cena musical afrolatina/diaspórica, que nos parece mais adequado para dar conta de processos culturais ambientados em localidades marcadas pela opressão colonial e a violência étnica-racial.
SEPARATION, INITIATION, AND RETURN IN THE PRISONER OF ZENDA NOVEL BY ANTHONY HOPE
Authors: Hrp Zainul Syaidin Azri , Satria Robby
Published: April 2024

Abstract
This research aims to identify the phases of the hero patterns in “The Prisoner of Zenda” a novel written by Anthony Hope experienced by the main character as the hero. Campbell (2004) mentioned that the pattern is prominent in heroic fiction referred to as monomyth. This research uses a descriptive qualitative design to examine the intricacies of the analysis method by Ratna (2004) the method of library research was employed to gather the data, and the method of descriptive analysis by Ratna (2004) was used to analyze the data. This research was made to fulfill phases of hero patterns Separation, Initiation, and Return. The result of the research Rudolf Rassendyll as the hero has passed 15 stages of hero's patterns based on Campbell's theory only Woman as a temptress and The Magic Flight no found in The Prisoners of Zenda. The stages of the hero's patterns have the function of uncovering the quest that the hero wants to reach. This leads to the conclusion that hero’s patterns often follow the same pattern as theorized and mentioned in the theory of Joseph Campbell.
Keywords: Heroism, Hero Patterns, Separation, Initiation, Return, Preliminary Analysis
THE USE OF TRANSLANGUAGING IN PRAGMATICS CLASS AT STKIP PGRI SIDOARJO
Authors: Yunmar Kintan Kirana , Sabat Yuliyanto , Prasetyo Yudy , Putranto Henry Rio
Published: April 2024

Abstract
This research focused on exploring the usefulness of translanguaging used by pragmatics lecturers in teaching and English learning in EFL classroom at STKIP PGRI Sidoarjo. The grand theory used in this research was translanguaging conception by Cen Williams (1980s). This type of research was qualitative approach using observation. The data of this research were fragmented statements taken from voice recordings and notes concluded by the researcher. The data source was supporting data in the form of visual documents taken from observations, interviews, and documents non-visual taken from the documentation. Data collection techniques in this study were observation, interviews, sound recording and documentation. The data analysis technique in this study was thematic analysis. Based on the analysis, there were 2 findings from the perspective translanguaging practice in English as a Foreign Language class. First, the research results reveal that using Mixed languages ​​keep EFL students motivated to learn languages English better and to be able to achieve their dreams. Second, the results of further research reveal that the use translanguaging makes it easier for lecturers to explain material to EFL students.
Keywords: Translanguaging, EFL Learner, EFL Teacher, Pragmatics, Language Translation Practice
Marine natural products: potential agents for depression treatment
Authors: Wang Xunqiang , Yang Cece , Zhang Xing , Ye Caiping , Liu Wenping , Wang Chengmin
Published: April 2024

Depression is a common psychiatric disorder. Due to the disadvantages of current clinical drugs, including poor efficacy and unnecessary side effects, research has shifted to novel natural products with minimal or no adverse effects as therapeutic alternatives. The ocean is a vast ecological home, with a wide variety of organisms that can produce a large number of natural products with unique structures, some of which have neuroprotective effects and are a valuable source for the development of new drugs for depression. In this review, we analyzed preclinical and clinical studies of natural products derived from marine organisms with antidepressant potential, including the effects on the pathophysiology of depression, and the underlying mechanisms of these effects. It is expected to provide a reference for the development of new antidepressant drugs.
Discovery of a hyperalkaline liquid condensed phase: significance toward applications in carbon dioxide sequestration
Authors: Bewernitz Mark A. , Schneider Jacob , Camiré Christopher L. , Kang Seung-Hee , Bourcier William L. , Wade Richard , Constantz Brent R.
Published: April 2024

Bicarbonate ion-containing solutions such as seawater, natural brines, bovine serum and other mineralizing fluids have been found to contain hyperalkaline droplets of a separate, liquid condensed phase (LCP), that have higher concentrations of bicarbonate ion (HCO3−) relative to the bulk solution in which they reside. The existence and unique composition of the LCP droplets have been characterized by nanoparticle tracking analysis, nuclear magnetic resonance spectroscopy, fourier transform infrared spectroscopy, dissolved inorganic carbon analysis and refractive index measurements. Carbon dioxide can be brought into solution through an aqueous reaction to form LCP droplets that can then be separated by established industrial membrane processes as a means of concentrating HCO3−. Reaction of calcium with the LCP droplets results in calcium carbonate precipitation and mineral formation. The LCP phenomenon may bear on native mineralization reactions and has the potential to change fundamental approaches to carbon capture, sequestration and utilization.
Metabolic performance and feed efficiency of black soldier fly larvae
Authors: Eriksen Niels Thomas
Published: April 2024

The black soldier fly (BSF), Hermetia illucens, is used in entomoremediation processes because its larvae can use a variety of organic residues with high efficiency. However, feed efficiencies are variable and characterized by uncertainties. Recently developed growth and metabolic performance models have predicted across different studies that BSF larvae have used 53%–58% of the feed components they have assimilated, in terms of carbon equivalents, for growth throughout their lifetime when reared on chicken feed. This is termed their average net growth efficiency. The remainder of the carbon has been lost as CO2. However, mass balances made under similar conditions show that the weight gained by BSF larvae corresponds to only 14%–48% of the feed substrates removed, indicating substrate conversion efficiency. Both performance indicators show even greater variability if more feed substrates are considered. Feed assimilation and growth rates, costs of growth, maintenance, and larval lifespan have been shown to affect how efficiently BSF larvae convert feed into growth. The differences between average net growth efficiencies and substrate conversion efficiencies further indicate that feed is often not used optimally in entomoremediation processes and that the overall yield of such processes is not determined by larval performance alone but is the result of processes and interactions between larvae, substrates, microbes, and their physical environment. The purpose of this study is to illustrate how quantification of the metabolic performance of BSF larvae can help improve our understanding of the role of the larvae in entomoremediation processes.
Peptidomics-based identification of antihypertensive and antidiabetic peptides from sheep milk fermented using Limosilactobacillus fermentum KGL4 MTCC 25515 with anti-inflammatory activity: in silico, in vitro, and molecular docking studies
Authors: Pipaliya Rinkal , Basaiawmoit Bethsheba , Sakure Amar A. , Maurya Ruchika , Bishnoi Mahendra , Kondepudi Kanthi Kiran , Singh Brij Pal , Paul Souparno , Liu Zhenbin , Sarkar Preetam , Patel Ashish , Hati Subrota
Published: April 2024

This study investigated the synthesis of bioactive peptides from sheep milk through fermentation with Limosilactobacillus fermentum KGL4 MTCC 25515 strain and assessed lipase inhibition, ACE inhibition, α-glucosidase inhibition, and α-amylase inhibition activities during the fermentation process. The study observed the highest activities, reaching 74.82%, 70.02%, 72.19%, and 67.08% (lipase inhibition, ACE inhibition, α-glucosidase inhibition, and α-amylase inhibition) after 48 h at 37°C, respectively. Growth optimization experiments revealed that a 2.5% inoculation rate after 48 h of fermentation time resulted in the highest proteolytic activity at 9.88 mg/mL. Additionally, fractions with less than 3 kDa of molecular weight exhibited superior ACE-inhibition and anti-diabetic activities compared to other fractions. Fermentation of sheep milk with KGL4 led to a significant reduction in the excessive production of NO, TNF-α, IL-6, and IL-1β produced in RAW 267.4 cells upon treatment with LPS. Peptides were purified utilizing SDS-PAGE and electrophoresis on 2D gels, identifying a maximum number of proteins bands ranging 10–70 kDa. Peptide sequences were cross-referenced with AHTPDB and BIOPEP databases, confirming potential antihypertensive and antidiabetic properties. Notably, the peptide (GPFPILV) exhibited the highest HPEPDOCK score against both α-amylase and ACE.
Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease
Authors: Cui Ji , Zhai Qilong , Chen Mengjie , Yang Zhu
Published: April 2024

Introduction

Intrahepatic cholestasis of pregnancy (ICP), the most prevalent liver disorder specific to pregnancy, affects approximately 1.5%-4% of pregnancies. However, the influence of ICP on cardiovascular disease (CVD), including hypertension (HTN) and coronary artery disease (CAD), has not been thoroughly investigated.

Methods

This study explores the causal relationship between ICP and CVD (HTN, CAD) using Mendelian Randomization (MR). Utilizing summary-level data from Genome-Wide Association Studies (GWAS), we applied the inverse-variance weighted (IVW) method, supplemented by sensitivity and reverse MR analyses, to ascertain robustness.

Results

Our findings reveal significant causal links, indicating ICP notably increases the risk of CVD (P = 0.001), hypertension (HTN, P = 0.024), and coronary artery disease (CAD, P = 0.039). A two-step MR analysis highlighted the mediation role of lipid profiles, with LDL, TC, and Apo-B contributing to increased CVD risk by 25.5%, 12.2%, and 21.3%, respectively. Additionally, HTN was identified as a mediator in the ICP-CAD association, accounting for a 14.5% mediation effect.

Discussion

The results underscore the genetic predisposition of ICP to elevate CVD risk and the critical mediating role of lipid levels, emphasizing the need for vigilant lipid monitoring and early intervention in individuals with ICP.
Preliminary strontium isotope (87Sr/86Sr) baselines for the Bjäre Peninsula and Halland in southern Sweden
Authors: Macheridis Stella , Sandstrom Michael , Svensson Andreas , Wilhelmson Helene , Berggren Åsa , Wranning Per
Published: April 2024

During the last decade, the application of strontium isotope analysis (87Sr/86Sr) has increased rapidly. The understanding of the strontium isoscape and the construction of a strontium isotope baseline in southern Scandinavia are biased toward Denmark and southwestern to eastern Scania. We report the results of new baseline samples in Halland and the Bjäre Peninsula, adding to the rich strontium isotope library that exists for southern Scandinavia. We add nuance to the previous divisions of Scania, in which the Bjäre Peninsula is not well represented. The results show that the Bjäre Peninsula is characterized by relatively low 87Sr/86Sr values gathered in the preliminary baseline 0.7100 ± 0.0024 (2σ, n = 8), similar to that of southwest Scania and Zealand in Denmark. There is a greater variation and higher values among the Halland samples. Together with previously published faunal samples, a preliminary 87Sr/86Sr baseline for Halland is 0.7122 ± 0.0055 (2σ, n = 24). We apply these baseline results to archaeological cases, both human and animal, from recent excavations in the Bjäre Peninsula. The results imply that there was a certain degree of mobility and interaction across the landscape in this region of southern Scandinavia in prehistory.
Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients
Authors: James David W. , Quintela Marcos , Lucini Lisa , Al Kafri Nour Al Abdullah , Healey Gareth D. , Jones Nicholas , Younas Kinza , Bunkheila Adnan , Margarit Lavinia , Francis Lewis W. , Gonzalez Deyarina , Conlan R. Steven
Published: April 2024

Decidualisation, the process whereby endometrial stromal cells undergo morphological and functional transformation in preparation for trophoblast invasion, is often disrupted in women with polycystic ovary syndrome (PCOS) resulting in complications with pregnancy and/or infertility. The transcription factor Wilms tumour suppressor 1 (WT1) is a key regulator of the decidualization process, which is reduced in patients with PCOS, a complex condition characterized by increased expression of androgen receptor in endometrial cells and high presence of circulating androgens. Using genome-wide chromatin immunoprecipitation approaches on primary human endometrial stromal cells, we identify key genes regulated by WT1 during decidualization, including homeobox transcription factors which are important for regulating cell differentiation. Furthermore, we found that AR in PCOS patients binds to the same DNA regions as WT1 in samples from healthy endometrium, suggesting dysregulation of genes important to decidualisation pathways in PCOS endometrium due to competitive binding between WT1 and AR. Integrating RNA-seq and H3K4me3 and H3K27ac ChIP-seq metadata with our WT1/AR data, we identified a number of key genes involved in immune response and angiogenesis pathways that are dysregulated in PCOS patients. This is likely due to epigenetic alterations at distal enhancer regions allowing AR to recruit cofactors such as MAGEA11, and demonstrates the consequences of AR disruption of WT1 in PCOS endometrium.
Circulating tumor DNA: from discovery to clinical application in breast cancer
Authors: Xu Jiachi , Gao Hongyu , Guan Xinyu , Meng Jiahao , Ding Shirong , Long Qian , Yi Wenjun
Published: April 2024

Breast cancer (BC) stands out as the cancer with the highest incidence of morbidity and mortality among women worldwide, and its incidence rate is currently trending upwards. Improving the efficiency of breast cancer diagnosis and treatment is crucial, as it can effectively reduce the disease burden. Circulating tumor DNA (ctDNA) originates from the release of tumor cells and plays a pivotal role in the occurrence, development, and metastasis of breast cancer. In recent years, the widespread application of high-throughput analytical technology has made ctDNA a promising biomarker for early cancer detection, monitoring minimal residual disease, early recurrence monitoring, and predicting treatment outcomes. ctDNA-based approaches can effectively compensate for the shortcomings of traditional screening and monitoring methods, which fail to provide real-time information and prospective guidance for breast cancer diagnosis and treatment. This review summarizes the applications of ctDNA in various aspects of breast cancer, including screening, diagnosis, prognosis, treatment, and follow-up. It highlights the current research status in this field and emphasizes the potential for future large-scale clinical applications of ctDNA-based approaches.