bluuebunny/crossref_metadata_2025 huggingface dataset:
IPSC-induced podocytes from a BORS patient with EYA1 gene mutation showed glucocorticoid-resistant and cytoskeletal rearrangement
Authors: Li Guanyu , Lu Di , Xu Liujing , Zhou Shumin , Zhang Jiayi , Wu Lijuan , Shi Lingna , Wang Lili , Lin Xiaoqing , Ma Zhigang , Liu Ming , Gao Xia
Published: December 2024

The primary cause of branchio-oto-renal syndrome (BORS) is mutations in the EYA1 gene. This study aimed to explore the impact and underlying mechanisms of EYA1 mutations on podocyte injury. We collected clinical and genetic data from a 4-year-old girl diagnosed with BORS and her family. Induced pluripotent stem cells (iPSC) were derived from peripheral blood mononuclear cells of both the patient and healthy individuals, which were differentiated into podocytes in vitro. RNA-seq was used to analyze differentially expressed genes in both groups. Here, the proband, along with his brother and mother, exhibited symptoms of BORS. WES analysis identified a heterozygous splicing variant at the EYA1 locus: c.1050 + 5G > A, inherited from his mother. The proband was initially glucocorticoid-resistant. After tacrolimus treatment, his urine protein/creatinine ratio significantly improved. Compared to healthy individuals, patient-derived podocytes displayed increased motility and pronounced cytoskeletal rearrangement. Dexamethasone was ineffective in ameliorating the pathological damage induced by puromycin aminonucleoside in patient-derived podocytes. RNA-Seq results indicated significant downregulation of cell adhesion molecule signaling pathway expression in patient-derived podocytes compared to healthy controls. In BORS patients with EYA1 mutations, podocytes exhibit cytoskeletal reorganization and enhanced motility in vitro while showing resistance to steroid treatment-indicating a unique damage response that warrants further investigation.
Hospital Healthcare Resource Utilization Outcomes Following Total Hip Arthroplasty with ACTIS™ Hip System and Accolade® II Femoral Hip System: A Comparative Analysis
Authors: Jamieson Robert , Gupta Anshu , Ruppenkamp Jill , Peng Mingkai , Varughese Biju , Diaz Rodrigo
Published: December 2024

Background
The ACTIS™ Hip System (ACTIS), a cementless, medial collared, triple tapered hip system from DePuy Synthes was launched in the US in 2016. This study was designed to evaluate healthcare resource utilization and hospital costs, among patients who underwent total hip arthroplasty (THA) with ACTIS compared to the Accolade® II Femoral Hip System (Accolade II).
Methods
The PINC AI (PREMIER) Healthcare Database was used for analysis. Patients > 21 years of age, undergoing cementless THA from January 2016 to September 2023, and implanted with ACTIS or Accolade II, were identified. Primary outcomes included length of hospital stay and 90- and 365-day all-cause readmission. Secondary outcomes included hip revision, and all-cause and hip related revisit and readmission rates within 90- and 365-days and hip-related complications at 90 and 365 days. The exposure was the device type (ACTIS vs. Accolade II). Study variables included patient demographics, insurance type, comorbidities, and hospital characteristics. Cohorts were balanced using covariate balance propensity score method and generalized linear model was used to compute outcomes.
Results
14,238 ACTIS and 17,578 Accolade II patients were included in the analysis. Balanced cohorts had an average age of 66 years, 57% were female, and 57% were Medicare recipients. Length of stay was significantly shorter for ACTIS (1.65 days vs. 1.93 days for control, p-value < 0.01). The 90-day all-cause readmission rate was 2.62% for ACTIS and 3.15% for Accolade II and the mean difference of 0.52% [0.13–0.92%] was significantly lower (p-value < 0.01) for ACTIS. The mean difference for 365-day all-cause readmission was also significantly lower for ACTIS (1.19% [0.53–1.84%], p-value < 0.01). The rates of hip-related complications, such as dislocation and deep infection were lower for the ACTIS compared to the Accolade II cohort, both at 90- and 365-day post-surgery. Total cost of care at 365-day follow-up was also lower for ACTIS compared to the Accolade II cohort.
Conclusions
The comparative analyses showed favorable outcomes for the ACTIS cohort in terms of shorter length of stay, fewer all-cause readmissions, fewer discharges to skilled nursing facility and lower cost at 365-day follow-up compared to Accolade II.
Engineering the T6SS of Pseudomonas for targeted delivery of antibacterial and antifungal effectors
Authors: Pérez-Lorente Alicia Isabel , Araujo-Garrido Mario , de Vicente Antonio , Romero Diego , Molina-Santiago Carlos
Published: December 2024

Background Bacteria employ diverse molecular systems, such as the type VI secretion system (T6SS), to outcompete other microorganisms and adapt to ecological niches. The T6SS is a versatile nanomachine capable of delivering toxic effectors into neighboring cells, providing advantages in bacterial interactions. In recent years, T6SSs have been proposed as promising tools for engineering selective antimicrobial platforms.
Results In this study, we successfully engineered P. putida KT2440 to heterologously express and release T6SS effectors. The expression of Tse1, an effector from Pseudomonas chlororaphis, induced sporulation in plant-beneficial Bacillus strains via a T6SS-dependent mechanism, particularly when Tse1 was paired with a PAAR protein. Similarly, the engineered strain effectively inhibited Aeromonas hydrophila growth using the phospholipase toxin TplE from Pseudomonas aeruginosa. Furthermore, antifungal activity was achieved by coexpressing Tfe2, an effector from Serratia marcescens, with VgrGs, resulting in increased reactive oxygen species levels and cellular damage in Botrytis cinerea. Importantly, the T6SS was also employed to deliver non-T6SS effectors such as chitosanase, demonstrating its versatility in degrading fungal cell walls.
Conclusions Our findings demonstrate that the T6SS can be engineered to deliver both canonical and noncanonical effectors, providing a robust platform for targeted antimicrobial and antifungal applications. The modularity of the system enables precise pairing of effectors with structural components such as VgrG and PAAR proteins, optimizing delivery efficiency. These engineered systems provide new opportunities for the development of biocontrol strategies in agriculture, microbiome modulation, and potential therapeutic applications. Future advancements in bioinformatics and protein engineering will further increase the specificity and functionality of T6SS-based delivery systems, offering innovative tools for managing microbial ecosystems and addressing global challenges in health and agriculture.
Revealing and cleaning of an onion layer: scientific Insights into the Restoration of Giacomo Balla’s "Ritratto d’uomo / Eugenio Riva"
Authors: Macchia Andrea , De Caro Tilde , Colapietro Marcello , Carnazza Paola
Published: December 2024

The restoration of Giacomo Balla’s Ritratto d’uomo / Eugenio Riva has unveiled unexpected insights into the intersection of historical restoration practices and modern scientific techniques. This study documents the discovery and analysis of onion residues on the painting's surface, attributed to a mid-20th-century cleaning attempt. Leveraging cutting-edge analytical tools—such as FTIR ATR spectroscopy, SEM/EDS, and UV imaging—researchers explored the chemical and morphological effects of this unconventional treatment. Additionally, the article highlights innovative solutions, including enzymatic cleaning formulations and polar solvent systems, which were employed to safely restore the artwork. This multidisciplinary approach not only restored the painting’s aesthetic coherence but also contributed to the broader understanding of restoration challenges posed by historical interventions
HBV Screening, Antiviral Prophylaxis, and Reactivation in Rituximab-Treated Patients: Insights from a Large Retrospective Cohort Study
Authors: Baker Fadi Abu , Tatour Mifleh , Neeman Ziv , Dola Tamar , Saadi Tarek , Hazzan Rawi
Published: December 2024

Hepatitis B virus (HBV) reactivation is a recognized complication of rituximab therapy, necessitating effective screening and prophylactic antiviral therapy to mitigate risks. This study evaluated trends in HBV screening, antiviral prophylaxis, and reactivation rates among rituximab-treated patients using data from Clalit Health Services from 2000 to 2022. A retrospective analysis included 1,857 adult patients (mean age 60.5 years; 50.4% male), most treated for hematologic malignancies. Screening rates improved significantly over time, with full HBV screening increasing from under 40% in 2000–2005 to over 80% after 2014 (p < 0.0001). Of the cohort, 10.9% had positive HBV serology (8.6% anti-HBc+; 2.3% HBsAg+), and prophylactic antiviral therapy was initiated in 122 of 188 positive cases. Prophylaxis rates rose from below 40% in the early years to over 80% after 2017 (p < 0.0001). Six cases of HBV reactivation were documented, all in patients with hematologic malignancies. No significant reactivation or liver enzyme elevations were observed in non-hemato-oncologic settings. The findings highlight the substantial reduction in HBV reactivation achieved through enhanced screening and prophylaxis and emphasize the importance of risk-based management strategies, particularly tailored follow-up for non-hemato-oncologic patients, to optimize clinical outcomes.
CT-based radiomics models using intralesional and different perilesional signatures in predicting the bioactivity of hepatic alveolar echinococcosis
Authors: Hou Juan , Zhang Simiao , Li Shouxian , Zhao Zicheng , Zhao Longfei , Zhang Tieliang , Liu Wenya
Published: December 2024

Objectives
To evaluate the performance of CT-based intralesional combined with different perilesional radiomics models in predicting the bioactivity of hepatic alveolar echinococcosis (HAE).
Methods
This study retrospectively analyzed preoperative CT data from 303 patients with HAE confirmed by surgical pathology (bioactivity positive, n = 182; bioactivity negative, n = 121). The patients were randomly assigned to the training cohort (n = 242) and test cohort (n = 61) at a ratio of 8:2. The radiomics features were extracted from CT images on the portal vein phase. Four radiomics models were constructed based on gross lesion volume (GLV), gross combined 10mm perilesional volume (GPLV10mm), gross combined 15mm perilesional volume (GPLV15mm) and gross combined 20mm perilesional volume (GPLV20mm). The best radiomics signature model and clinical features were combined to establish a nomogram. Receiver operating characteristic curve (ROC) and decision curve analysis (DCA) were used to evaluate the predictive performance of models.
Results
Among the four radiomics models, the GPLV20mm model performed the highest prediction performance with the area under the curves (AUCs) in training cohort and test cohort was 0.876 and 0.802, respectively. The AUC of the clinical model was 0.753 in the training cohort and 0.699 in the test cohort. The AUC of the nomogram model based clinical and GPLV20mm radiomic signatures was 0.922 in the training cohort and 0.849 in the validation cohort. The DCA showed that the nomogram had greater benefits compared with the single radiomics model or clinical model.
Conclusion
CT-based GPLV20mm radiomics model can better predict the bioactivity of HAE. The nomogram model showed the best predictive performance.
Dog-Mediated Rabies Virus Transmission is Driven by Free-Roaming Dog Density, Haiti 2018 – 2023
Authors: Beron Andrew J. , Keshavamurthy Ravikiran , Boutelle Cassandra , Wallace Ryan
Published: December 2024

Eliminating dog-to-dog rabies virus transmission, the primary cause of > 70,000 human deaths annually, remains a challenge in over 100 countries due to the difficulty of implementing effective dog vaccination and population management programs. Despite the development of tools to optimize vaccine impact, rabies virus transmission dynamics are still not well-understood, largely due to insufficient surveillance. Utilizing data from Haiti’s advanced rabies surveillance system, we analyzed likely rabies cases, adjusted for a 1% detection rate, to estimate the true rabies burden in Haitian dogs. Our study calculated the basic reproductive rate (R0) of rabies, finding a strong logarithmic relationship between R0 and free-roaming dog density (R2 = 0.88), with R0 falling below 1.0 when dog density fell below 11 per km². This association suggests that denser free-roaming dog populations, likely reflecting more urbanized communities, may perpetuate rabies transmission, providing critical insights for targeting effective vaccination efforts.
Robotic transmitral resection of floating left ventricular thrombus
Authors: Cullen Paul , Chou Nai-Kuan , Wei Ling-Yi , Yu Hsi-Yu , Chi Nai-Hsin
Published: December 2024

Background
Despite the role of surgery in the management of left ventricular (LV) thrombi remaining controversial, robotic LV thrombectomy has emerged as a viable treatment option. This study aimed to present our successful experience with a robotic mitral program, detailing the operative technique.
Materials and Methods
We conducted a retrospective analysis of our institutional database to identify patients who underwent LV thrombectomy using the da Vinci robot system. Subsequently, serial echocardiograms and short- and long-term outcomes were reviewed and analyzed using descriptive statistics.
Results
A total of five patients (median age: 46 years) were included in this study. All patients presented with a floating LV thrombus and a history of embolization. Among them, four patients experienced reduced heart function, none had coronary artery disease, three experienced dilated cardiomyopathy. Complete resection was achieved in all cases, with no postoperative deaths, strokes, or major complications. Additionally, LV function showed improvement during follow-up periods. Postoperative anticoagulation was continued for two years in one patient and one year in the remaining patients. No recurrence or further embolic events were observed during the median follow-up period of 6 years.
Conclusion
Robotic LV thrombectomy yields excellent outcomes and should be considered early for patients with floating LV thrombi. However, further investigation is warranted to determine the optimal timing of this intervention and its role in the treatment paradigm, including whether these results can be extrapolated to patients with other forms of mobile thrombus and/or to support surgery as the primary prevention of systemic embolization.
Exploring Faculty Development Initiatives in Medical Education in resource-limited settings: Perspectives and Challenges
Authors: Ahmed Arwa , Batt Alan
Published: December 2024

Background: Faculty Development Programs (FDPs) are an integral part of institutional priorities to support staff members in leveraging the skills necessary to deliver quality education and enhance the overall learning experience. Little is known about their impact in resource-limited settings. Therefore, the objective of this study was to evaluate the perception of medical and health faculties toward FDP by exploring staffs’ views on their performance, learning environment, and challenges that hinder the program’s implementation.
Method: Data were collected through a survey of faculty members to assess participants’ perceptions of the CPD programs
Result:There was a 77% response rate (n=103) to the survey from the targeted sample size of 134. . The majority of the staff members (90.3%, n = 93) perceive FDP activities as beneficial for enhancing their teaching abilities, while 70.9% (n = 73) see improvement in research practices, and 54.4% (n = 56) observe benefits to their clinical skills. Fewer respondents (46.6%, n = 48) reported improvements in their scientific publications. However, several challenges were identified with time constraints perceived as a major obstacle to effective program implementation.
Conclusion:In a resource-limited setting, evaluating the program's effectiveness plays a pivotal role in improving its activities. Providing additional resources, enhancing institutional support, and improving accessibility to activities can strengthen the program’s success, ultimately benefiting both staff and students.
Centralization or Decentralization: Sales and Logistics Control Strategies of E-commerce Platforms in the Competitive Supply Chain
Authors: XIA Dejian , SHI Guoqiang , GAO Yanhong
Published: December 2024

In the context of differentiated logistics competition, this paper adopts the Hotelling model to investigate the strategic game between two oligopolistic e-commerce platforms, which dominate the e-commerce supply chain, regarding the combination of sales and logistics modes. Through profit comparison and numerical simulation, we uncover the following insights: (1)When logistics services are heterogeneous, even if sales is homogeneous, the two platforms adopt distinctly different control strategies for both sales and logistics, resulting in a single separated Nash equilibrium in the game. (2)Neither platform has a dominant strategy, and any combination of sales and logistics under self-operation or third-party operation may become the platform's strategic choice, leading to multiple separated Nash equilibria between the two parties. (3)Both parties cannot simultaneously maximize their profits, but a platform that adopts full centralization, especially in logistics, achieves a higher profit level than a competitive platform. Therefore, both parties have a need for integrated operations that seek centralized logistics and sales, which can easily lead them into a "prisoner's dilemma" where both suffer losses.
Prevalence, Knowledge, and Attitude toward Parkinson’s Disease among the general population in Saudi Arabia
Authors: Khan Salahuddin , Alzakari Meshal , Alzkari Faisal , Alsuhaibani Renad , Alabdulkarim Alanoud , Alghanmi Amjad , Moiz Muhammad Abdul , Huda Arwa , Salahuddin Amra , Althobaiti Ahmed
Published: December 2024

Background: Parkinson’s disease is a progressive disease that causes damage to parts of the brain. It is the most common motor brain condition. This study aims to investigate the prevalence, knowledge, and attitude toward Parkinson’s disease among the general population in Saudi Arabia.
Objective: To investigate the prevalence, knowledge, and attitude toward Parkinson’s disease among the general population in Saudi Arabia.
Methods: This cross-sectional study was conducted in Saudi Arabia from July 20 to November 20, 2024, targeting adults aged 18 and older. Participants (n = 385) were randomly selected via social media platforms, using a bilingual (Arabic and English) online questionnaire. The survey included demographics, self-reported PD prevalence, knowledge, and attitudes. Data was analyzed using SPSS (version 28), with ethical approval obtained.
Results: A total of 330 participants were surveyed, mostly young (292, 88.5% aged 18–24), female (269, 81.5%), and students (281, 85.2%). Nearly half (162, 49.1%) had heard of PD, but only 81 (24.5%) showed good knowledge, with misconceptions about causes and treatment. Commonly recognized symptoms included hand tremors (292, 88.5%) and poor balance (210, 63.6%), while awareness of non-motor symptoms was low. Most participants (319, 96.7%) supported public education, and 310 (93.9%) recommended social support for PD patients.
Conclusion: This study emphasizes gaps in public knowledge about Parkinson's disease in Saudi Arabia. The results highlight the need for educational efforts to improve understanding and address misconceptions.
Categories: Neuroscience
Enhancing Spectrum Utilization and Energy Efficiency in OFDMA Networks through Optimized Subcarrier Allocation and Power Control
Authors: M Raghavendra Y , M Asha , G Manjula , M Latha , sindgi Anupama , Prasad S N
Published: December 2024

The increasing demand for efficient spectrum utilization and energy conservation in wireless communication systems has highlighted Orthogonal Frequency Division Multiple Access (OFDMA) as a key enabling technology. However, existing optimization techniques, such as Genetic Algorithms, Machine Learning-based methods, and the Water-filling Algorithm, face challenges related to scalability and computational complexity. This study presents an optimized framework for enhancing spectrum utilization and energy efficiency in OFDMA networks, modelled with 10 users, 256 subcarriers, a system bandwidth of 100 MHz, and operating at a Signal-to-Noise Ratio (SNR) of 20 dB. Utilizing 16-QAM modulation and adhering to a per-user power constraint of 2 units, the proposed framework integrates adaptive subcarrier allocation and power control. The methodology employs simulation-based analysis to evaluate performance under realistic network conditions. Results demonstrate significant improvements, achieving an average spectrum utilization of 0.69141 and an average energy efficiency of 1.4447, indicating the method’s effectiveness in maximizing resource allocation while minimizing energy consumption. This research bridges theoretical models with practical applications, contributing to the advancement of cognitive radio networks by providing a scalable and efficient solution for spectrum access. The proposed approach reduces interference and enhances operational efficiency, offering valuable insights for the deployment of large-scale OFDMA systems in next-generation communication networks.
Analisis Kesalahan Penggunaan Bahasa Indonesia dalam Artikel Ilmiah SMA Al Khoiriyah Sumbergempol
Authors: Hidayah Sa'adatun Nuril , Setyawan Bagus Wahyu , Rakhmawati Ani , Tawandorloh Ku-Ares
Published: December 2024

The purpose of learning Indonesian is to hone students' language skills. One of the things that is developed is the skill of writing scientific articles. In practice, there are still many errors in students' scientific article work. For this reason, the purpose of this study is to describe and analyze the misuse of the Indonesian language in scientific articles of students of Al Khoiriyah Sumbergempol High School. The data source of this research is 34 articles by students. The data collection technique used in this study is a documentary study technique and is assisted by an instrument in the form of a data recording card. The analysis of research data includes the stages of data reduction, data presentation, and conclusion drawn. The results of data analysis found two categories of errors, namely errors in the use of spelling and errors in the preparation of the structure of scientific articles. Writing errors include mistakes in the use of letters, use of words, use of punctuation, and writing terms/absorption of foreign languages. Structural errors include errors in the preparation of titles, abstracts, editorial sections, research results, and conclusion/closing sections. This is important to be a concern and a reflection material for future learning as well as prepare the skills of students who will continue their studies in higher education.
Penggunaan Media Wordwall untuk Meningkatkan Hasil Belajar Siswa Kelas X SMAN 1 Pademawu
Authors: Damayanti Riska , Wachidah Liana Rochmatul
Published: December 2024

Indonesian language learning that keeps up with the times can be realized through the use of internet-based technology media. Technology-based media will maximize the targets of Indonesian language learning. Many learning platforms can be applied in learning Indonesian, some are paid and some are free. One of the applications that can be used in learning Indonesian is Wordwall. In this study, Wordwall is applied in Indonesian language learning on the material of observation report texts in high school. The subjects of this research are 10th-grade students at SMAN 1 Pademawu. This research is in the form of classroom action research. The research results show that the students' success rate in mastering observation report texts at the pre-cycle stage was 42.8%, at the cycle I stage was 64%, and at the cycle II stage was 85.7%. This indicates an increase in the graph of students' mastery of observation report text material after using Wordwall as a learning medium. There are still several obstacles in the use of that media, namely network issues and students' concentration not yet improving to the maximum.
FIBRILLARY GLOMERULONEPHRITIS: THE IMPORTANCE OF DIAGNOSTIC APPROACH
Authors: Patel Hardik , Konnur Abhijit , Gang Sishir , Soni Shailesh
Published: December 2024

Fibrillary Glomerulonephritis(FGN) is rare glomerular disease characterized by microscopic hematuria, proteinuria, hypertension and renal insufficiency.Crescentic pattern of FGN is uncommon and would be diagnosed as rapidly progressive renal failure unless Electron Microscopy and/ or special stains are done. We present a case report of a young male who presented as nephrotic syndrome who was diagnosed to have crescentic GN and was revised to crescentic FGN after electron microscopy and immunohistochemical staining with DNAJB9 stain. Patient treatment was changed to Rituximab. The case emphasizes the use of Electron microscopy and special stains in diagnosing rare diseases and importance of diagnostic approach to Fibrillary Glomerulonephritis.
UMUT VE DİRENÇ: MÜLTECİ SORUNUNUN ÇAĞDAŞ SANATTA SUNUMU
Authors: Yüksel Hanife Neris
Published: December 2024

Bu makalede, 21. yüzyılın karmaşık ve insani meselelerinden biri olan mülteci krizi, politik çatışmalar, ekonomik zorluklar ve savaşların yıkıcı etkileriyle şekillenen küresel bir trajedi olarak ele alınmaktadır. Milyonlarca insanın kendi topraklarından zorla ayrılmasına ve mülteci kamplarında ya da yabancı ülkelerde yeni bir hayat mücadelesine zorlanmasına yol açan bu durum, çağdaş sanatın etik, kültürel ve politik bir sorgulama alanına dönüşmüştür. Bu bağlamda, Alfredo Jaar, Ai Weiwei, Yara Said, Khaled Barakeh, Issam Kourbaj ve Bouchara Khalili gibi sanatçıların eserleri, mülteci krizini heykel, fotoğraf, enstalasyon, video gibi farklı medya aracılığıyla ele almakta; izleyiciyi bu sorunun çok boyutlu yapısı üzerine düşünmeye davet etmektedir. Sanatçılar, eserleriyle yalnızca bir görsel anlatı sunmakla kalmamakta, aynı zamanda mülteci krizinin altında yatan etik sorumluluklara ve politik mücadelelere dikkat çekmektedir. Makale, çağdaş sanatın mülteci krizine yaklaşımını ve bu yaklaşımın toplumsal ve politik etkilerini analiz ederek, sanatın toplumsal değişime olan katkısını anlamayı amaçlamaktadır.
Asset Management decision-making through data-driven Predictive Maintenance – an overview, techniques, benefits and challenges
Authors: Krishna Menon Madhu , Tuladhar Rabin
Published: December 2024

Over the years, industrial asset management has significantly transformed from being an unavoidable resource consumer to a value creator involving multi-criteria decision-making and optimisation. This is particularly important in the scenario of Industry 4.0, which offers more opportunities for improved maintenance effectiveness. This review examines the literature covering the evolving area of data-driven Predictive Maintenance (PdM) within engineering asset management. The work explores current and emerging practices for managing asset degradation, with emphasis on the domain of Prognostics and Health Management (PHM). Next, it examines the opportunities for data-driven methods, associated techniques, and data sources to incorporate data-driven PdM into the maintenance decision-making portfolio. The text concludes by discussing the opportunities and constraints related to data-driven PdM for three identified asset data streams. The paper offers insights for researchers and practitioners interested in utilising data-driven approaches to improve asset reliability, improve maintenance strategies and manage asset complexities.
Memorial Plaques in the Russian Empire, the USSR, and the Russian Federation: Cataloguing and Studies
Authors: Ablova Elizaveta E.
Published: December 2024

Memorial plaques are a widespread form of perpetuating history. The earliest memorial plaques appeared in Russia in the XIX century. Their popularity peaked in the second half of the XX century, and they retain their relevance to this day. The article describes the general trends and approaches to the installation and study of memorial plaques in the Russian Empire, the USSR, and the Russian Federation. The first national legislation and cataloguing of memorial plaques started in the Soviet period. Nowadays, memorial plaques are a subject of interdisciplinary research. The comparative analysis relied on the following criteria: installation details, functional characteristics, protection, social attitude, academic interest, etc. The analysis revealed general and special characteristics of memorial plaques throughout Russian history. The author focused on the memorial plaques installed in the Kemerovo Region by the regional All-Russian Voluntary Society for the Protection of Cultural and Historical Monuments.
Hybrid multi-module for short-term forecasting of river runoff considering spatio-temporal features
Authors: Chen Hao , Kang Ling , Zhou Liwei , Zhang Wentao , Wen Yunliang , Ye Jinwang , Qin Rui
Published: December 2024

Runoff forecasting is crucial for water resources management, demanding precise models. This study proposes a runoff forecasting model that utilises a hybrid variational mode decomposition (VMD), convolutional neural network (CNN), and long short-term memory network (LSTM) based on the attention mechanism (AM) to enhance the accuracy and stability of runoff forecasting. The volatility of the runoff sequence was significantly reduced by the VMD. The AM focused on extracting the most critical information from the features. The VMD–CNN–AM–LSTM model, using the two-stage decomposition forecasting framework, was used to predict daily runoff at the Jianli (JL) hydrological station in the section from Yichang to JL from 1 October 2006 to 30 October 2022. This model outperformed the model without the hybrid of VMD and/or AM in forecasting runoff, with a root mean square error value of 646.160, a mean absolute error value of 424.124, a mean absolute percentage error value of 2.54%, and an R2 value of 0.9933. Model stability was assessed using the bias-variance, which was found to be significantly more stable than the model without VMD and AM. The VMD and AM optimises runoff forecasting at the target station by utilising upstream stations’ runoff. This improves the accuracy and stability of the model, providing technical support for water resources planning and management.
Uma descrição alucicrazy do estado da arte dos blends do português brasileiro
Authors: Viana Braga Emerson , Pacheco Vera
Published: December 2024

Este texto aborda sobre o processo do blend com foco específico no português brasileiro, propondo uma discussão sobre o estado da arte deste tipo de formação de palavra. Este fenômeno é um processo caracterizado pela mescla de duas bases, como em namorido (namorado + marido). A pesquisa sobre blends possui uma história extensa, com vários linguistas e estudiosos contribuindo para sua compreensão. Diante disso, este artigo oferece uma visão geral da evolução de pesquisas relacionadas a este fenômeno, com destaque para o contexto do português brasileiro. Além disso, examina exemplos relevantes de blends nessa língua e discute sua utilização, além de quaisquer peculiaridades em comparação com outras línguas naturais. O objetivo é, portanto, apresentar conceitos e características dos blends, explorando, especificamente, os aspectos semânticos e fonológicos envolvidos no processo e discutindo se é concatenativo ou não concatenativo. Dada às diferentes maneiras para as formações de blends – compartilhando material fonológico, ou não –, é analisado, também, as tipologias adotadas por alguns linguistas para os distintos padrões de palavras formadas por esse processo.
A centralidade da água em La Femme cent couleurs, de Lorrie Jean-Louis
Authors: Rego de Almeida Danielle Grace
Published: December 2024

Em La Femme cent couleurs (2020), sua primeira antologia de poemas, Lorrie Jean-Louis constrói versos que, ao mesmo tempo em que produzem imagens delicadas, expressam fraturas advindas da exploração colonial. Sua escrita acessa as dores causadas pela colonialidade em curso no mundo contemporâneo, cuja segregação racial transforma pessoas negras em sujeitos de identidades fragmentadas e em permanente sentimento de perda. Relacionada a essas questões, encontra-se uma voz poética marcada pelas instabilidades de ser mulher numa sociedade profundamente cindida pelas desigualdades e violências de gênero. Nesta análise, pretende-se expor como essas temáticas são construídas através das figurações da água, que se constituem um tropo poético central e reatualizado ao longo de todo o livro.
Revisitando Variações Enigma sob o prisma da semiótica francesa: da tematização do primeiro amor à subversão do sagrado
Authors: Bibiano Ricardo , Magnoni Tocaia Luciano
Published: December 2024

Este artigo tem por objetivo apresentar alguns resultados de uma pesquisa que investigou discursos sobre sexualidade entre indivíduos same-sex-attraction (Sutton, 2015) na obra Variações Enigma, de André Aciman (2018). Para tanto, a pesquisa baseia-se no quadro teórico-metodológico proposto pela semiótica discursiva de linha francesa, ou semiótica greimasiana (Greimas, 1973; Greimas e Courtés, 1994; Bertrand, 2003), e seus desdobramentos no Brasil (Barros, 2002, 2008; Fiorin, 2008, 2009), circunvizinhados por alguns conceitos desenvolvidos no quadro da Análise materialista do discurso (Pêcheux, 1995, 2008) e pelas questões sobre sexualidade desenvolvidas por Foucault (2007) e por Freud (1996). Metodologicamente, este estudo, ao considerar a obra de Aciman como um discurso, uma vez que o discurso é uma das unidades de análise da teoria semiótica greimasiana, mapeou os procedimentos de disseminação dos temas e das figuras na obra e seus respectivos percursos temáticos e figurativos relativos a questões de sexualidade no período da infância do narrador, de forma a verificar como esses componentes da semântica discursiva, nível por excelência da manifestação da ideologia, reproduzem no texto os imaginários sociais. Além disso, por meio da análise das categorias de pessoa, tempo e espaço, analisaram-se os mecanismos e as estratégias de construção de efeitos de sentido propostos pelo autor em relação às projeções da enunciação. Os resultados, em um primeiro momento, indicaram que a concretização das relações de desejo e sexualidade se perfaz entre atores discursivos recipientes de um investimento figurativo parecidos entre si, isto é, ama-se aquele que é semelhante. Em um segundo momento, esses resultados permitiram avançar nossa interpretação da obra de Aciman, revelando como o percurso temático do primeiro amor teve como alicerce um percurso de subversão do sagrado, representado principalmente pela figura da capela normanda. Dessa análise semiótica, entendemos que a sexualidade encontrou sua concretude temático-figurativa na intersecção entre a busca por um objeto amoroso semelhante e a subversão simbólica do sagrado.
Como a linguagem molda a memória episódica
Authors: Camillo José Carlos
Published: December 2024

O enativismo radical defende que cognição básica não é composta por computações de informações representacionais. Diante dessa proposta, a memória episódica (de eventos que alguém viveu) pode se tornar um desafio para essa abordagem da cognição humana especialmente porque parece intuitivo que memórias representam os eventos passados. Neste artigo, esse problema será abordado a partir da discussão acerca de como a linguagem humana molda a memória episódica. Será argumentado que a linguagem afeta as funções da memória episódica de modo a concedê-la uma função comunicativa e, como tal, representacional.
economia restrita do falo
Authors: Borba Dutra Vinicius
Published: December 2024

O artigo analisa a crítica de Jacques Derrida, em “O carteiro da verdade”, ao falocentrismo concernente à lógica do significante proposta por Jacques Lacan. Para isso, mostramos como a desconstrução parte da concepção de que a aposta no falo é um dos modos de Lacan ser fiel à ideia de Sigmund Freud em torno da libido ser masculina. Derrida busca explicitar esse vínculo por meio da interpretação que o psicanalista francês produz do conto “A carta roubada”, de Edgar Allan Poe, uma vez que tal interpretação transformaria a literatura em ilustração da tese freudiana indicada acima. Retomar essa querela de Derrida com Lacan permite não só indicar a força efetiva da crítica desconstrutiva à economia restrita do falo como também defender a hipótese segundo a qual a cena da escrita de Derrida fica demasiadamente presa ao que conheceu de Lacan nos Escritos, o que permite supor que a psicanálise lacaniana possa ter outra teoria sexual que não apenas aquela que a desconstrução visa desmontar.
Acerca da causalidade formal-final e material-eficiente na teoria da percepção de Aristóteles:
Authors: Teixeira William
Published: December 2024

O objetivo desse artigo é tentar compreender como se processa a percepção visual, segundo Aristóteles. Para alcançar tal propósito, avançarei a hipótese interpretativa segundo a qual a ocorrência da visão é o resultado de uma ‘duplicidade causal’, na qual estão necessariamente envolvidos tanto fatores materiais, correspondentes à causa material-eficiente, quanto fatores ‘não-materiais’, referentes à causa formal-final. A escolha por privilegiar essa ‘duplicidade causal’ se deve ao fato que a mesma parece estar em perfeita consonância com o hilemorfismo aristotélico, algo que parece ser escamoteado tanto na interpretação ‘literalista’, quanto na ‘espiritualista’.
Eurico Alves Boaventura e a criação de um Almajesto sertanejo
Authors: São Paulo Yves
Published: December 2024

Na crônica/ensaio Sob ditame de rude Almajesto, o jurista, poeta e cronista baiano Eurico Alves Boaventura descreve uma miríade de técnicas e experiências desenvolvidas pelo povo do sertão para prever as épocas de chuva. Tecendo a descrição destas observações, traçamos paralelos entre a função popular criadora de uma episteme e os princípios da filosofia grega. Observamos, assim, as proximidades entre a vontade de criação de conhecimento que antecede os primeiros filósofos e a que rodeia o mundo sertanejo. Encerramos num exercício de imaginar como este pensamento se apresentaria numa linguagem filosófica.
ISTO NÃO É UM RITUAL
Authors: Heidrich Bisol Luciano
Published: December 2024

O presente artigo discute os recursos de representação do feminino na obra de Eurípides (c. 484 - 406 a.C.) a partir da crítica teatral encontrada na comédia Tesmoforiantes (c. 411 a.C.), de Aristófanes (c. 446 – 386 a.C.). Na peça há a encenação de um ritual religioso realizado por mulheres na cidade de Atenas, durante o período Clássico. Como um fractal, Aristófanes desenvolve sucessivos desdobramentos a respeito da encenação dentro da encenação. Esta investigação se trata de uma pesquisa bibliográfica que tem como objetivo identificar o papel da música enquanto elemento mimético para o constructo do feminino na obra euripideana.
ESPAÇO EM TRANSE
Authors: Almeida Saulo Vinícius
Published: December 2024

A relação do espaço e da espacialidade na composição do objeto artístico foi importante foco dos debates da filosofia da arte e da estética durante o século XX. O presente artigo, se ancora no conceito de Stimmung de Gumbrecht para refletir sobre a recepção a partir da especialidade em sua dimensão material, escapando de uma fruição primordialmente analítica, crítica e distanciada, empregando, por vezes, o recorte da ambiência e em outros momentos, a atmosfera como conceitos fundamentais. Em seguida, com o intuito de ampliar o debate a partir das epistemologias de terreiro, propõe-se a noção de um espaço em estado de transe, composto por invisibilidades que se configuram como agentes ativos possuidores do condão de alterar os corpos a partir de seu desejo, de sua ética e historicidade e por esses corpos, alterar o mundo. A conclusão aponta a atmosfera como tessitura da teatralidade, alternado o papel do sujeito observador como seu agente para seu paciente, ou seja, para aquele que sofre o efeito. Ademais, aponta um questionamento: seria possível falar de um espaço em transe indiferente à presença de corpos humanos?
Economic Sanctions: How to Make International Trade a Legal Right Instead of a Privilege
Authors: Molodyko K.
Published: December 2024

The wave of new economic trade sanctions in the world needs the comprehension of the grounds and potential consequences of this phenomenon. The author summarizes the annual reports of the UN Special Rapporteur on the negative impact of the unilateral coercive measurers for 2015–2022. Also, the paper explains why the “broken windows theory” is relevant to unilateral economic sanctions imposed by developed countries against developing countries. Analyzing the results of voting in the UN for non-specific country sanction issue resolutions, the author proves that the developed countries and European developing countries except Russia usually support economic sanctions as a policy tool which is unlikely for non-European developing countries. The increase in multi-regionalism facilitated by imposed or potential economic sanctions is a factor which could lead to the collapse of the unilateral system of international trade regulations under the WTO scope. Finally, the paper offers to unblock the Doha Round of WTO negotiations through a switch from multilateral agreement ideology to plurilateral agreement ideology, starting from signing an in-depth and comprehensive anti-economic sanctions agreement initiated by the BRICS member states.
Risk-Based Approach as a Basic Element of the Tax Security of the States in the BRICS Countries
Authors: Ponomareva K. , Maslov K. , Mironova S.
Published: December 2024

This study is devoted to a comparative analysis of different models of the risk-based approach used in tax administration in the BRICS countries. The risk-based approach is widely recognized as the fundamental basis for defining and legally consolidating the tasks of tax administration bodies in modern conditions. According to this approach, the objectives of the tax administration are to identify, prevent and minimize threats to tax security in the course of the implementation of the full range of administrative functions in the tax sphere, as well as to work towards overcoming the consequences of the realization of threats. The authors propose the following points for conducting a comparison of the BRICS countries using tax risk assessment: the implementation of risk assessment in the practice of tax administration and the quality of its legislative regulation, the impact of risk indicators on the behavior of taxpayers and the impact of risk indicators on the effective implementation of tax control measures. In general, there is a high degree of similarity among all aspects of the risk-based approaches adopted in the BRICS countries. However, the methods of implementation and levels of legal certainty in laws differ from country to country.
La comprensión del movimiento antropológico en la desesperación. Kierkegaard y el desenvolvimiento del hombre en el yo
Authors: Baños Ballenas Leonardo Martin
Published: December 2024

En el presente texto se examina la relación del hombre consigo mismo, impulsada por su desesperación como desarrollo antropológico. Partiendo de la propuesta teórica de Søren Kierkegaard, se busca describir el recorrido dialéctico del hombre hacia sí mismo en relación con un absoluto, que le es externo. El hombre se define únicamente por su representación más inmediata, como un conjunto de carne y hueso, sino como espíritu. En su trascendencia, su vida no finaliza con el perecimiento de su cuerpo físico; de igual modo, el pecado, inherente a su ser, siempre lo acompaña. Inquieto consigo mismo, el hombre percibe su capacidad de transformarse hacia una forma más auténtica, capaz de alcanzar una realización. Esto responde a una teleología establecida por la existencia de Dios, aunque sin determinar el actuar del hombre. Por último, el proceso de actualización de sí mismo, desde su estadio estético hasta el religioso, puede entenderse como una progresión de menor a mayor grado de fe. En otras palabras, su transformación se da en cuenta de una existencia auténtica, alcanzada mediante un desarrollo impulsado por la desesperación.
Acta Memoriae
Authors: Novoa Francisco
Published: December 2024

En 2024, la Licenciatura en Filosofía de la Universidad Católica de la Santísima Concepción realizó diversas actividades académicas, como seminarios, talleres, coloquios y conferencias, abordando tanto los clásicos como debates actuales. Destacaron las Jornadas de Filosofía, la indexación de la revista Inmanere y actividades de extensión, promoviendo pensamiento crítico y compromiso con la verdad y el bien común.
Viscosity reduction of water-in-oil emulsion by phase inversion: surfactants performance and characterization
Authors: Nascimento Nariyoshi Yuri , Meneguelo Ana Paula , De Castro Santana Rejane
Published: December 2024

The phase inversion technique has received attention in the petroleum industry in order to decrease energy consumption. Crude oil emulsions with model brine solutions containing 1.5% wt NaCl and 1.0 wt.% surfactants were produced and evaluated on electrical conductivity, kinetic stability, microstructure and rheology. It was found that phase inversion occurred in the range of 20-40 wt.% of brine. Emulsions having 10-40 wt.% of brine and Triton-X-100 manifested lower phase separation than without surfactant or with Tween 80, while oil-in-water emulsions having 50 and 60 wt.% of brine and Triton-X-100 achieved the lowest value of viscosity. Thus, these results elucidate the influence of selected parameters on emulsions properties aiming to improve mobility and flowability by phase inversion of high viscous water-in-oil emulsion.
Proposição de princípios orientadores para uma transição energética justa
Authors: Brumatti Dayane Valentina , Chaves Gisele de Lorena Diniz , Siman Renato Ribeiro
Published: December 2024

O desenvolvimento econômico e social dos países é altamente dependente da regularização de um suprimento energético eficiente. Diante das projeções futuras de aumento da demanda global por energia, são necessárias estratégias que auxiliem os gestores políticos para alcançar a transição energética de forma que seja justa, sustentável e democrática. Assim, esse trabalho objetivou elencar dez princípios norteadores, que os entes federativos devem levar em consideração para alcançar essa transição energética. Para isso buscas foram realizadas em Scopus, Web of Science, Google Scholar, e IPEA. Como resultados, foram demonstradas pesquisas que listaram princípios relacionados ao tema. E construído os princípios desta pesquisa, sendo: acessibilidade; investimentos, linhas de crédito e incentivos fiscais; sustentabilidade ambiental; sustentabilidade financeira; empregabilidade, realocação e capacitação de mão-de-obra; políticas; coordenação internacional; confiabilidade e oferta energética diversificada; sociedade civil e intervenções bem-sucedidas. Os princípios propostos podem trazer novos elementos para a tomada de decisões relacionada às questões energéticas atuais.