bluuebunny/crossref_metadata_2025 huggingface dataset:
Mycotic Aortic Arch Aneurysms: Open versus Endovascular Management – An Institutional Experience
Authors: Sun Neelamjingbha , Pandey Ashutosh Kumar , Manchikanti Sriram , Gupta Aditya , Rajeev Akash , Muniswamy Sandeep , Jain Prashant , Pitchai Shivanesan
Published: January 2024

Background:

Mycotic aortic aneurysms are rare disorders, affecting patients with co-morbidities, and associated with a high risk of aneurysm expansion, rupture, and sepsis.

Aims and Objectives:

In this study, we present our experience on the management of patients with mycotic arch aneurysms.

Materials and Methods:

From January 2020 till July 2023, eight patients were admitted in our hospital for management of mycotic aortic arch aneurysm. On a case-to-case basis, the management was selected for each patient and consent was taken for the same.

Results:

Four patients underwent open repair and four endovascular repair, out of which three underwent hybrid arch repair. While only one patient in the open group expired in the immediate postoperative period due to sepsis, the remaining patients have been on follow-up for 1month-1year. There was no mortality in the immediate post TEVAR period. However, three of the patients who underwent TEVAR required re-admissions and re-intervention, with one patient developing aorto-esophageal fistula. Two of these patients expired in a span of 3months-1.5years post TEVAR.

Conclusion:

In patients with mycotic arch aneurysm, open surgical repair should be the modality of choice in fit surgical patients and endovascular management can be used as a bridge therapy, keeping in mind the risks of residual infection in the aorta which can lead to re-interventions and re-admissions.
Compassion satisfaction, burnout, and secondary traumatic stress among nurses after the second wave of the COVID-19 pandemic
Authors: Dixit Priyanshi , Srivastava Saumya P. , Tiwari Surya Kant , Chauhan Soni , Bishnoi Ravi
Published: January 2024

Background:

Nurses frequently experience compassion fatigue and burnout, which impact their personal lives and patient care. The COVID-19 pandemic additionally caused stress, uncertainty, and fear of death among healthcare professionals.

Aim:

To assess professional quality of life (ProQoL) among nurses after the second wave of the COVID-19 pandemic.

Material and Methods:

A web-based cross-sectional study was conducted among 203 nurses using a purposive sampling technique in the month of September to December 2021. Data were collected using a self-administered ProQoL scale version 5.

Statistical Analysis:

Descriptive and inferential statistics were used. Kolmogorov–Smirnov test, Mann–Whitney U, and Kruskal–Wallis H test were used. Bivariate correlations were used to correlate the main variables. Multiple linear regression analysis was also performed.

Results:

The majority of the nurses reported a moderate level of compassion satisfaction (CS) (62.6%), burnout (BO) (66.0%), and secondary traumatic stress (STS) (63.1%). Residence and education emerged as a factor whether the nurses experienced BO or STS, respectively. Additionally, CS negatively correlated with BO (r = -0.732: P < 0.001) and STS (r = -0.141: p-0.04).

Conclusions:

The majority of the nurses experienced moderate levels of CS, BO, and STS after the second wave of the COVID-19 crisis and nurse patient–ratio emerged as a significant factor to predict CS, BO, or STS. Hence, effective measures need to be implemented by hospital administration to enhance the nurses’ satisfaction and reduce fatigue and burnout.
Prevalence of generalized anxiety disorder among patients attending medicine outpatient department in a tertiary care center: A cross-sectional study
Authors: Veloumourougane Gokoul , Ramamurthy Parthasarathy , Thilakan Pradeep , Raghuraman Preethy , Vimal Joseph
Published: January 2024

Background:

Generalized anxiety disorder is commonly underdiagnosed and undertreated in medical settings.

Aim:

The objectives of this study were to determine the prevalence and correlates of generalized anxiety disorder among patients presenting to medicine outpatient department in a tertiary care centre.

Materials and Methods:

A cross-sectional observational study was conducted among the patients visiting the outpatient department of General Medicine in a tertiary care teaching hospital. Sociodemographic and clinical parameters were collected using a structured pro forma. All patients were administered Generalized Anxiety Disorder-7 (GAD-7) to screen for the presence of generalized anxiety disorder. Patients who score 10 or more underwent a semi-structured evaluation using a generalized anxiety disorder module of Structured Clinical Interview for DSM-IV Axis I disorders.

Results:

Two hundred and fifty patients were recruited for the study. The mean age of the participants was 40.66 ± 12.8 years. More than one-fourth of them had diabetes mellitus and about one-fifth of the participants had systemic hypertension and hypothyroidism. Thirty five (14%) participants screened positive on GAD-7 scale. On detailed evaluation using SCID-I, 19 (7.6%) participants were confirmed to have a generalized anxiety disorder. Female gender was associated with the presence of GAD.

Conclusion:

One in thirteen patients presenting to the medicine outpatient department were found to have generalized anxiety disorder. Female patients had a greater prevalence of generalized anxiety disorder compared to male patients.
Evaluation of tumor-educated platelet long non-coding RNAs (lncRNAs) as potential diagnostic biomarkers for colorectal cancer
Authors: Tabaeian Seidamir Pasha , Eshkiki Zahra Shokati , Dana Fatemeh , Fayyaz Farimah , Baniasadi Mansoureh , Agah Shahram , Masoodi Mohsen , Safari Elahe , Sedaghat Meghdad , Abedini Paria , Akbari Abolfazl
Published: January 2024

Introduction:

Cancer-derived circulating components are increasingly considered as candidate sources for non-invasive diagnostic biomarkers. This study aimed to investigate the expression of tumor-educated platelet (TEP) long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) patients and determine whether it could be served as a potential tool for CRC diagnosis.

Materials and Methods:

Relative quantitative real-time PCR (qRT-PCR) was used to detect the expression levels of three cancer-related platelet-derived lncRNAs CCAT1, HOTTIP, and XIST in 75 CRC patients and 42 healthy controls. Quantitative data were analyzed by SPSS (IBM Corp., Armonk, NY, USA) for comparison of cancer and non-cancer individuals. The receiver operating characteristic (ROC) curve analysis was further performed to assess the diagnostic values of lncRNAs within the CRC patients.

Results:

The expression levels of lncRNAs colon cancer associated transcript 1 (CCAT1) (P = 0.006) and HOXA transcript at the distal tip (HOTTIP) (P = 0.049), but not X-inactive specific transcript (XIST) (P = 0.12), were significantly upregulated in CRC patients compared to healthy individuals. However, there were no significant correlations between platelet lncRNAs and clinicopathological characteristics, including sex, age, tumor location, differentiation, and size (all at P > 0.05). The area under the ROC curve (AUC) of the lncRNA CCAT1 was 0.61 (sensitivity, 71%; specificity, 50%).

Conclusion:

TEP lncRNA CCAT1 is detectable in the circulation of CRC patients and could be considered as a potential diagnostic biomarker.
Durable response to docetaxel in a case of primary seminal vesicle adenocarcinoma with zinner syndrome
Authors: Fatima Sheereen , Shaikh Imran N. , Athikari Nevitha
Published: January 2024

Primary adenocarcinoma of the seminal vesicles is a rare tumor. Congenital seminal vesicle cysts are often associated with unilateral renal dysgenesis or agenesis (Zinner syndrome). Zinner syndrome is a rare congenital malformation represented by a group of characteristics: ipsilateral renal agenesis, ejaculatory duct obstruction, and seminal vesicle cyst. There have been 214 cases in the literature with abdominal pain and lower urinary tract symptoms as the most common presentation. Most cases are diagnosed incidentally. We report a case of a 39-year-old male presenting with recurrent hematuria for 12 years, diagnosed as metastatic primary clear cell adenocarcinoma of seminal vesicle with Zinner syndrome. He was managed symptomatically with radiation therapy, hormonal therapy, and palliative chemotherapy. He is living with a well-controlled disease at present.
Cardiac migration of an implanted hepatic fiducial marker used for stereotactic body radiation therapy - A case report
Authors: Soliman Youstina , Antony Febin , Vivian Mark , Venkatraman Sankar , Nashed Maged
Published: January 2024

Stereotactic body radiation therapy (SBRT) has been increasingly used to treat liver malignancies because large doses of radiation can be delivered precisely to the target with a rapid dose falloff. Real-time tracking of implanted fiducial markers (FMs), combined with respiratory gating, further improves the accuracy of treatment delivery and reduces the dose to critical structures. There have been reports of migration of the FMs after implantation for SBRT. Calypso beacons, which use the electromagnetic wave reflections for the image guidance, have recently been used for image-guided liver SBRT. In the literature, there are no reports on the migration of Calypso beacons to the heart after implantation in the liver. In this report, we detail the first case of such migration. Respiratory-gated SBRT guided by the Calypso system was planned for our patient, who developed liver metastases in segments 6 and 5/4B shortly after the completion of radical chemoradiotherapy for anal squamous cell carcinoma. One of the three Calypso beacons inserted in the liver under computed tomography (CT) guidance was found to have migrated to the right ventricle, as seen in CT simulation images. SBRT was delivered with respiratory gating using the remaining two beacons. A fluoroscopic imaging performed during treatment confirmed the migrated marker to the right ventricle. Patient denied any cardiac symptoms and SBRT were delivered uneventfully. Ten months later, the patient died of disease progression.
Comparative evaluation of quality of life in oral cancer patients undergoing 3-dimensional conformal radiation therapy with or without concomitant chemotherapy – A longitudinal study
Authors: Parate Prajakta M. , Mahajan Aarti M. , Prakash Nilima , Pradeep GL , Harnekar Shirin H. , Sadhwani Vaishali A.
Published: January 2024

Objectives:

To assess and compare the quality of life (QOL) in Oral Cancer patients undergoing 3-DCRT with or without concomitant Chemotherapy at three different time intervals.

Materials and Methods:

This unicentric longitudinal study included 50 patients of oral cancer undergoing 3-DCRT with or without concomitant chemotherapy. QOL was recorded using the EORTC H and N 35 Questionnaire at baseline, end of treatment (EOT), and 3 months after treatment.

Results:

Maximum deterioration of most QOL domains were noted at End of treatment (EOT) in all the patients. A highly statistically significant difference was noted between different time intervals with the highest scores noted at the EOT (P < 0.01). There was a statistically significant difference in patients undergoing 3DCRT with chemotherapy when compared to those with 3DCRT without chemotherapy (P < 0.05).

Conclusion:

There is substantial deterioration in QOL at the EOT after head–neck irradiation by 3-DCRT with or without concomitant Chemotherapy although it gradually improves over time. However, 3DCRT results in clinically meaningful and statistically better QOL scores at 3 months after treatment compared to baseline and EOT.
Translation and pilot validation of Hindi, Marathi, and Bangla translation of quality of life EORTC module (QLQ-SH-22) for assessing sexual health-related quality of life
Authors: Krishnatry Rahul , Rane Devankshi , Krishnamurthy Revathy , Pawar Purva , Chakraborty Debanjan , Gaikwad Utpal , Ghosh Suman , Datta Debanjali , Anup Akanksha , Das Sayan , Ambre Tejaswi , Makwana Divya , Gudi Shivkumar , Engineer Reena
Published: January 2024

Aim:

To translate and validate the European Organization for Research and Treatment for Cancer (EORTC) module for assessing the sexual health-related quality of life in cancer patients (QLQ-SH22), in Hindi, Marathi, and Bangla languages for clinical use.

Methods and Results:

The EORTC QLQ-SH-22 was translated into Hindi, Marathi, and Bangla by adopting standard guidelines given by EORTC. Initially, the original questionnaire was forward translated by two separate translators, followed by the reconciliation of the forward translations by a third person. This was followed by two back translations of the reconciled version into English by two other translators. These back-translated questions were then compared with the original EORTC questions for accuracy, and once acceptable, a preliminary questionnaire was prepared in all three languages. These questionnaires were then pilot tested with 30 patients (10 for each language) diagnosed with any of the cancers in the pelvic region who are expected to be at risk of sexual quality of life due to tumor or treatment like pelvic radiotherapy. Participated patients had never seen or filled the questionnaire before, each patient was interviewed after filling the questionnaire for difficulty in answering, confusion, difficulty understanding, or if any of the questions were upsetting and if patients would have asked the question differently.

Results:

None of the patients reported any changes or suggestions for all the three translations. All the translated questionnaires were well understood by all the patients. Pilot testing reports were sent to EORTC. After reviewing the entire report of Hindi, Marathi, and Bangla translations, these questionnaires were approved by the EORTC translation unit. The questionnaires are reliable with Cronbach’s α for Hindi, Marathi, and Bangla being 0.69, 0.66, and 0.86, respectively.

Conclusion:

The final Hindi, Marathi, and Bangla translations of SH 22 have been approved by the EORTC and can be used to assess the sexual health of cancer patients in routine oncology practices and/or clinical studies.
Compressive Intrapericardial Hematoma Following Thoracotomy to Seal Coronary Artery Perforation
Authors: Shukla Madhu , Mohan Jagdish Chander
Published: January 2024

A 68-year-old male developed cardiac tamponade secondary to coronary artery perforation following percutaneous coronary artery intervention. He underwent thoracotomy to seal the perforation of the acute marginal branch of the right coronary artery. Following sealing of perforation with application of cyanoacrylate to the right atrioventricular groove, the patient remained stable with minimal pericardial effusion for 1 month and later developed a large (6 cm × 5 cm) intrapericardial hematoma compressing the right ventricular inflow with intermittent fever. The patient declined repeat surgery and showed some regression of hematoma and a decrease in trans-tricuspid pressure gradients with colchicine after 1 month. The case is reported for its rarity with a review of literature.
Fibrin-associated large B-cell lymphoma arising in an endovascular graft: first case report in Korea
Authors: Pak Min Gyoung , Roh Mee Sook
Published: January 2024

Fibrin-associated large B-cell lymphoma (FA-LBCL) is an extremely rare subtype of LBCL that consists of microscopic aggregates of atypical large B cells in the background of fibrin. Here, we report the first case of FA-LBCL in Korea. A 57-year-old male presented with a large amount of thrombus in the thoracic aorta during follow-up for graft replacement of the thoracoabdominal aorta 8 years prior. The removed thrombus, measuring 4.3 × 3.1 cm, histologically exhibited eosinophilic fibrinous material with several small clusters of atypical lymphoid cells at the periphery. The atypical cells were positive for CD20 by immunohistochemistry and for Epstein-Barr virus by in situ hybridization. The Ki-67 proliferation rate was 85%. The patient was still alive with no recurrence at the 7-year follow-up after thrombectomy. Although the diagnosis can be very difficult and challenging due to its paucicellular features, pathologists should be aware of FALBCL, which has likely been underestimated in routine evaluations of thrombi.
Aluminum Alloy, Extrusions 5.6Zn - 2.5Mg - 1.6Cu - 0.23Cr (7075-T6, 7075-T6510, 7075-T6511) Solution Heat Treated, Stress Relieved by Stretching when Required and Precipitation Heat Treated
Authors:   AMS D Nonferrous Alloys Committee
Published: January 2024

This specification covers an aluminum alloy in the form of extruded bars, rods, wire, profiles, and tubing.
Filler Metal, Aluminum Brazing 10Si - 4.0Cu (4145)
Authors:   AMS D Nonferrous Alloys Committee
Published: January 2024

This specification covers an aluminum alloy in the form of wire, sheet, foil, pig, grains, shot, and chips (see 8.6).
The psychosocial impact on the future adult life of sexually abused children
Authors: Elenita Fîntîneanu (Buzgure) Georgeta
Published: January 2024

This research paper delves into the depth and complexity of the psychosocial impact in adult life of childhood sexual abuse, with a focus sexual abuse without penetration. Childhood sexual abuse is a major trauma that can have long-term effects on mental health, interpersonal relationships, and adaptation to various aspects of adult life. Through the analysis of existing research and case studies, this paper highlights the various consequences and influences that can persist in the lives of adults who were victims of sexual abuse in their childhood. We have demonstrated the symptomatic emotional, behavioral, and psychophysical manifestations specific to anxiety disorders, depression, and post-traumatic disorders of the subjects studied. Difficulties in establishing and maintaining intimate relationships were observed, as well as tendencies to distort reality. The relevance of this study comes from the focus on the sexual abuse without penetration, which has been shown to be easy to ignore, both by the victim and the expert (psychologist, psychotherapist, counselor, social worker). As a result, the consequences in adult life may be erroneously attributed to other types of trauma, which substantially increases the risk of re-traumatizing the victims. Future research can focus on expanding the statistical sample and moving towards quantitative methods, which would increase accuracy and representativeness for larger populations.
Ensinar e aprender Matemática por meio de Atividades de Vida Autônoma
Authors: Oliveira Mario Donizete Rodrigues de , Vilas Bôas Sandra Gonçalves
Published: January 2024

Apresentamos, neste artigo, o Contexto de Investigação Higiene Oral, no qual abordamos as unidades temáticas: Álgebra, Números e Probabilidade e Estatística, a partir da rotina diária dos alunos. Como objetivo geral, delimitamos investigar possibilidades de promover o ensino de matemática como uma prática natural e espontânea, que possam estimular o desenvolvimento pessoal e coletivo, visando à realização do indivíduo e da comunidade como um todo. Para isso, realizamos uma pesquisa qualitativa e instituímos quatro etapas: Estudo bibliográfico; Construção de tarefas/materiais pedagógicos; Produção de dados/Desenvolvimento das tarefas e Análise dos dados. Ainda, as tarefas realizadas baseadas na Atividade de Vida Autônoma — AVA permitiram a todos os alunos uma efetiva participação pelo fato de fazerem parte de seu dia a dia, independentemente do seu grau de dificuldade.
Desenvolvendo o conhecimento didático de futuros professores de Matemática com Estudo de Aula e Robótica Educacional
Authors: Souza Crhistiane da Fonseca
Published: January 2024

Essa investigação envolveu dezesseis alunos de um curso de Licenciatura em Matemática, de uma universidade federal brasileira, em uma disciplina de estágio supervisionado, cujo objetivo foi compreender as contribuições do estudo de aula e da robótica educacional na formação de futuros professores de Matemática. Em uma abordagem qualitativa, os dados foram recolhidos por meio da observação participante, notas de campo, análise documental, questionários, entrevistas e gravação em áudio das sessões de planejamento e reflexão. Os resultados mostram que os participantes desenvolveram seu conhecimento didático, no que tange ao conhecimento matemático para o ensino, elaboração e condução de tarefas investigativas com os robôs, condução de aulas de cunho exploratório, e ao desenvolvimento do conhecimento sobre o pensamento matemático dos alunos.
DDR-Zeitschriften
Authors: Fröhlich Vincent , Podewski Madleen
Published: January 2024

To this day, GDR magazines have hardly been found worthy of a closer analytical look. As the present essay will argue, they have been treated primarily as containers for propaganda. In the introduction to this special issue on GDR magazines, the authors discuss why this has been the case so far and why GDR magazines in particular would be worth an examination. The preface pleads for a conscious and more differentiated approach to the history and the cultural relevance of a central media format of the GDR: its magazines. Periodical and magazine studies deal mostly with magazines from Western capitalist societies. GDR magazines, however, originated in a completely different environment. The authors explain why, when exploring these objects, long-established and proven methods of periodical research must always be questioned first. To complement this, the introduction draws on a number of exemplary short analyses in an attempt to make initial suggestions of dealing academically with GDR magazines. Based on these observations, theses are developed and presented on what could distinguish GDR magazines or what might be the focus of future GDR magazine research. And finally, the essay will feature selected GDR magazines as well as insights from the workshop that gave birth to this special issue.
The Influence of supply chain management dimensions on the performance of electric cable companies in Jakarta
Authors: Khoe Marika , Rakhman Abdullah
Published: January 2024

A good and effective company supply chain determined around 60% of the company's sustainability. In detail, strategic supplier partnerships, customer relationships, information sharing, and information quality positively affect company performance. To investigate this notion, the authors conducted the study in an electric cable company in Jakarta among stakeholders who had lived in Jakarta for the past six months chosen by the census. The results show that strategic supplier partnership, information sharing, and information quality affect company performance. The most influential variable on the company's performance is information sharing. Customer relationship shows a positive but not significant effect on company performance. The research found that strategic supplier partnerships, customer relationships, information sharing, and information quality can explain the variance in company performance of 63.2%.
Modelo de reconfiguración óptima de la transmisión
Authors: Tovar-Barragán Olivier , Becerril-Gordillo Carlos Antonio
Published: January 2024

En este trabajo se presenta el problema de la reconfiguración óptima de la red de transmisión. Se muestra la forma en la que se construye el modelo matemático que se usa para resolver la problemática, haciendo una extensión del tradicional modelo de flujos óptimos, adicionando variables binarias para describir la conexión y desconexión de líneas de transmisión (tema principal de la reconfiguración óptima). Se utiliza un sistema pequeño de tres nodos para ejemplificar a detalle la construcción del modelo para luego extenderlo en la solución de un sistema de prueba de 14 nodos y otro más de 41 nodos (sur de Brasil) vía una implementación en AMPL usando CPLEX. Se muestran las diferencias económicas de usar un modelo de reconfiguración óptima contra la solución tradicional de flujos óptimos, traducidas en una reducción en el costo total de operación de cada sistema.
Combinatorial analysis: mathematics investigations by high school students at the Federal Institute of Tocantins
Authors: Oliveira Cynthia Souza , Geller Marlise , Pereira Filho Albano Dias , De Sousa Lilissanne Marcelly
Published: January 2024

This article is based on a study on mathematical research carried out with 2nd grade high school students at the Federal Institute of Tocantins. The investigation is placed in a qualitative perspective, based on Ponte's typology (2009). The objective of the research was to develop and apply activities that would enable students to develop mathematical investigation regarding the study of Combinatorial Analysis. The purpose was to investigate the impact of this experience on students, trying to understand not only the way they formulate questions and hypotheses, how they design and consolidate the choice of information, analyze the data they collected and also the disseminated results obtained. During the completion of the task, there was the role of teacher guiding the tasks and as it unfolded, conclusions were perceived which ensure that it is advantageous, both for teachers and learners and even though the activities carried out surprisingly promoted non-mechanized learning.
Transcriptome profiling of the gills to air exposure in mud crab Scylla paramamosain
Authors: Fan Sigang , Guo Yihui , Cheng Changhong , Huang Xiaolin , Ma Hongling , Guo Zhixun , Yang Qibin , Liu Guangxin , Gao Yougen
Published: January 2024

The mud crab Scylla paramamosain is a valuable commercial mariculture crab worldwide. During the ebb tide or when transported to market, crabs suffer underlying air exposure stress. Gills tissue is the first tissue to cope with this stress. In this study, the transcriptome of S. paramamosain gills from the control group (CG) and experimental group (EG) were sequenced, assembled, and compared. A total of 7,425,620,293 bp and 6,741,616,977 bp clean data were found in EG and CG, respectively. A total of 38,507 unigenes (42.78%) were annotated successfully. 13,626 differentially expressed genes (DEGs) were up-regulated, and 6,502 DEGs were down-regulated. The DEGs related to immunity, apoptosis, metabolism, and ion exchange were detected. DEGs were enriched significantly into the KEGG pathways related to metabolism and immunity. These results proved that more material and energy were required, and immune defense was enhanced when the crab was under air exposure stress. The present study provides the first-gill transcriptomic analysis challenged with air exposure stress in S. paramamosain under air exposure stress, which will be useful to clarify the molecular mechanisms of air exposure adaptation.
Claustros académicos y su contribución con la calidad de los doctorados en educación en Chile
Authors: Hidalgo Gutiérrez Paulina , Molina Díaz Cristian
Published: January 2024

La Comisión Nacional de Investigación en Ciencia y Tecnología (CONICYT) en los noventa, hoy llamada Agencia Nacional de Investigación y Desarrollo (ANID), comenzó a trabajar con el objetivo de regular la creación y validación de los programas de postgrado en Chile, y en específico en el cuerpo académico. El propósito de este trabajo es identificar la composición del perfil de los académicos del claustro y su contribución con la calidad de los doctorados en Educación en Chile.  Se realizó un análisis descriptivo, de la información obtenida desde la base de datos Sistema de Información de Educación Superior (SIES) del Ministerio de Educación y un análisis cualitativo de los claustros con base cienciométrico de los programas. En el período 2017-2022 se desarrollaron doce programas de Doctorado en Educación. Los programas acreditados pertenecen a universidades del Consejo de Rectores (CRUCH) y poseen claustros con líneas de investigación a fines con las líneas de investigación de los programas en estudio, otorgando sostenibilidad de calidad a los doctorados, no así los programas no acreditados. Se concluye que la acreditación de Doctorados en Educación depende de un cuerpo académico de calidad, con líneas de investigación definidas alineadas con las investigaciones de dichos programas, y sus consecuencias son tener un programa de Postgrado de calidad y niveles mínimos de acreditación.
Factores que influyen en la aceptación de la telesalud en mujeres peruanas
Authors: Gallegos Ruiz Conejo Ada Lucía , Londoño-Celis Wilmer , Rodríguez Correa Paula Andrea , Rodríguez Zavala Luisa Adriana , Bouroncle Velásquez Mauricio Renato , Vega-Mori Luis , Martínez Valera Pedro
Published: January 2024

La telesalud, fundamental durante la pandemia de COVID-19, enfrenta desafíos para su plena legitimación. La brecha digital y resistencia cultural son obstáculos, pero ofrece beneficios como la superación de barreras geográficas y socioeconómicas. La investigación busca identificar factores que determinan la aceptación de la telesalud en mujeres peruanas. El abordaje es de tipo descriptivo con un enfoque cuantitativo. Se realizaron encuestas a 503 mujeres universitarias en Lima, revelando confianza en médicos y actitudes positivas hacia la tecnología, aunque persiste la desconfianza en la seguridad de la información. La ansiedad informática y la influencia social son destacadas. Los resultados sugieren interés y disposición hacia la telesalud, subrayando la importancia de condiciones facilitadoras y expectativas de apoyo, especialmente en el contexto universitario. La investigación aboga por políticas universales para democratizar el acceso digital, enfocándose en grupos marginados como mujeres. Estos hallazgos son esenciales para profesionales de la salud y políticas de salud, destacando la necesidad de programas de apoyo en la comunidad universitaria para fomentar la aceptación y confianza en la telesalud.
ENDO-ß-1,4-GLUCANASE ENZYME ACTIVITIES OF SOME Trichoderma spp. AGAINST Rhizoctonia solani Kühn.
Authors: ELIBOL ILERI Ceren , GUCLU Coskun
Published: January 2024

Some enzymes are secreted by biocontrol agents, which are increasingly preferred in agricultural control, and suppress the pathogen of diseases and decrease its growth and effects. Rhizoctonia solani Kühn., one of these pathogens, causes many losses in plants by causing many diseases such as root cancer, root rot and collapsing. One of the microorganisms that damage the cell walls of such phytopathogens and is therefore preferred as a biocontrol agent is Trichoderma spp. In this study, the reaction of Trichoderma spp. against R. solani and changes in the synthesis of endo-ß-1,4-glucanase enzyme were determined. Eleven different Trichoderma spp. and R. solani Kühn. isolates were used as materials. The enzyme activity results indicated that the cellulase enzyme activity of the R. solani samples increased significantly compared to the control group. TVD3 showed the highest enzyme activity while TH4 was the lowest. The most significant difference from the control group was in TVD3 isolate. These results suggested that Trichoderma spp. showed a biochemical response for defending the plant against R. solani. The results also support the effectiveness of Trichoderma spp. as a biological control agent and potential for the development of new eco-friendly commercial products.
Aerodinamik Kuvvetlerin Demiryolu Araç Dinamiğine Etkilerinin İncelenmesi
Authors: BİLGİN Erbil , GÜÇLÜ Rahmi
Published: January 2024

Taşımacılık modları arasında tarihsel gelişim boyunca önemli bir yere sahip olan demiryolu taşımacılığı gelişen teknoloji ile birlikte yüksek hızlarda sağladığı güvenli ve konforlu seyahat ile yolcu taşımacılığı için tercih edilen bir ulaşım aracı haline gelmiştir. Özellikle yolcu taşımacılığında taşıma modları arasında tercih unsuru olan seyahat sürelerinin kısaltılması demiryolu araç gelişim süreçlerinde aerodinamik unsurların ön plana çıkmasına neden olmuştur. 1800 lü yıllardan itibaren başlayan demiryolu araçlarında hızlanma yarışı halen günümüzde devam etmektedir. Enerji verimliliği, sürüş güvenliği, yolcu konforu gibi birçok parametrede etken olan aerodinamik kuvvetlerin etkilerinin daha iyi anlaşılması için birçok çalışma yürütülmektedir, bu çalışma kapsamında literatürde yer alan matematiksel modellerden farklı olarak hem aracın hem de rüzgâr hızının değişken olduğu ve değişken aerodinamik verilerin gerçek zamanlı saha ölçümleri ile toplanması, kompleks bir dinamik simülasyon modeli ile simülasyonların gerçekleştirilmesi ile oluşturulmuştur. Yapılan çalışmada literatüre ilave olarak demiryolu araçlarında aerodinamik etkinin araştırılmasında yeni bir yaklaşım ortaya konulmuştur. Yapılan saha çalışmaları ve analizlerin sonucu olarak da belirlenen ölçüm hattı boyunca tekerlek ray kontağında meydana gelen kuvvet değişimleri irdelenmiştir.
Implementasi Sistem Monitoring Jaringan Menggunakan Libre Nms Pada Kecamatan Tarik
Authors: Adi Putra Lutfi , Alfan Rosid Mochamad , Setiawan Hamzah , Eviyanti Ade
Published: January 2024

Network monitoring is needed to find out the various types of equipment and systems that are connected. LibreNMS is one of network monitoring system that can make it easier for administrators to monitor the network and if there are any problems it can be resolved immediately. The features provided are numerous, making it easier to monitor network performance available and ready to use. This study aims to build a network monitoring system in Kecamatan Tarik using LibreNMS. The test results show if LibreNMS can show the condition of the network system and the use of various equipment which is properly monitored.
Os efeitos do nível de oposição sobre indicadores de performance técnica em jogos reduzidos e condicionados de futebol
Authors:   , Machado Victor Reis
Published: January 2024

A relação de oposição é inerente ao jogo de futebol. Ela tem sido estudada ao longo dos anos em situações de partidas oficiais e nos treinamentos em situações de jogos reduzidos e condicionados. É importante entender a relação dos níveis de oposição estabelecidos através de métricas individuais para permitir a individualização dos estímulos nos processos de ensino-aprendizagem-treinamento. Portanto, este estudo objetivou investigar os efeitos da manipulação dos níveis de oposição com base na tomada de decisão em jogos reduzidos e condicionados no futebol sobre os indicadores de performance técnica. A amostra foi composta por 121 jogadores de futebol masculino de clubes de formação (n=1) ou escolas de futebol (n=9) das categorias Sub-13 (n=62; 11,8±0,5 anos de idade, 4,3±1,8 anos de prática sistematizada) e Sub-15 (n=59; 13,9±0,7 anos de idade, 5,4±1,9 anos de prática sistematizada). Para a avaliação da tomada de decisão foi utilizada a plataforma TacticUP®. Os níveis de oposição foram estabelecidos conforme os índices da qualidade da tomada de decisão de acordo com os resultados do TacticUP® e, posteriormente, os jogadores realizaram jogos reduzidos e condicionados com diferentes níveis de oposição: I) Alta qualidade da tomada de decisão ofensiva vs. Alta qualidade da tomada de decisão defensiva; II) Alta qualidade da tomada de decisão ofensiva vs. Baixa qualidade da tomada de decisão defensiva; III) Baixa qualidade da tomada de decisão ofensiva vs. Alta qualidade da tomada de decisão ofensiva e, IV) Baixa qualidade da tomada de decisão ofensiva vs. Baixa qualidade da tomada de decisão defensiva. Para avaliação dos indicadores de performance técnica nos jogos reduzidos e condicionados foi utilizada a técnica da análise notacional. Os resultados encontrados indicam que os jogadores apresentaram melhor desempenho nos indicadores de performance técnica ofensivos (número de contatos com a bola, tempo de posse de bola, dribles, chutes, passes e recepções realizadas) e defensivos (dribles e chutes sofridos) quando enfrentam jogadores com baixa qualidade da tomada de decisão. Ademais, os indicadores de performance técnica que são influenciados variam de acordo com a qualidade dos níveis de oposição. Conclui-se que a manipulação dos níveis de oposição com base na tomada de decisão influência nos indicadores de performance técnica em jogos reduzidos e condicionados de futebol. Estes resultados permitem aos treinadores organizarem seus treinamentos de forma mais assertiva e adequada aos objetivos dos jogos e as capacidades táticas individuais dos jogadores. Palavras-chave: Jogos esportivos coletivos. Tática. Cognição. Tomada de decisão.
The paradox of spironolactone: A heart failure treatment with potentially harmful effects
Authors: Muhammad Roshan  , Muhammad Ahmad Nadeem  , Sahar Imran Khalfay
Published: January 2024

Madam,
Heart failure (HF) is a multifaceted clinical syndrome arising from a functional or structural cardiac condition that hampers the adequate filling or expulsion of blood into the systemic circulation. It is estimated that heart failure affects around 26 million people globally and significantly adds to healthcare expenditures on a worldwide scale1. Furthermore, in 2016, approximately 16 percent of deaths in Pakistan were due to heart related disorders. This number grew to 29 percent in 20222. HF can greatly diminish the functional capability of a patient and heighten the risk of mortality. Therefore, it is essential to accurately diagnose and proficiently manage this condition to improve the quality of life of the patient.
Spironolactone, the first mineralocorticoid receptor antagonist (MRA) to be developed, is prescribed for the management of hypertension, primary hyperaldosteronism, and peripheral oedema linked to cardiac failure3. When HF occurs and cardiac output decreases, it stimulates the renin-angiotensin-aldosterone system (RAAS) which in turn causes salt and water reabsorption and thus increases venous return to the heart which further contributes to congestive heart failure and heart fails to pump the additional fluid and pooling occurs. Here MRAs are very affective as they inhibit the function of aldosterone and hence fluid retention does not occur.
Unfortunately, the beneficial effects of spironolactone do not occur without substantial adverse effects. Firstly, spironolactone is associated with sexual adverse events due to its affinity for androgen and progesterone receptors. There have been reports of male patients experiencing gynecomastia and breast pain. Secondly, spironolactone has been classified as potassium sparing diuretic hence hyperkalemia (defined as serum K+ > 5.5 mEq/L) is a common side effect3.  Hyperkalemia can manifest as muscle weakness or paralysis, metabolic acidosis, cardiac conduction abnormalities, and life-threatening cardiac arrhythmias4. These cardiac arrythmias can have serious consequences, including cardiac arrest and stroke.
In conclusion heart failure, if not treated immediately, can be fatal. Spironolactone is a drug used for management of heart failure; however, it has some detrimental effects on the cardiovascular system such as development of serious cardiac arrythmias. Hyperkalemia, due to potassium sparing nature of MRAs, is the primary cause of these life-threatening effects thus it is recommended to assess serum potassium levels and renal function of a patient with heart failure before prescribing spironolactone. Moreover, patients who are being treated with spironolactone should be periodically monitored to prevent any casualty.
Increased antimicrobial resistance against azithromycin during COVID: role of irrational utilization
Authors: Tanwir Sidra , Sabah Arif , Khatoon Ambrina , Afridi Faisal Iqbal
Published: January 2024

Objective: To assess the use of azithromycin during coronavirus disease-2019 pandemic and its impact on antimicrobial resistance in an urban setting.
Method: The retrospective, cross-sectional study was conducted on two different data sets. The first data set was of inpatients (N = 300) during the first wave of COVID 19 i.e. January to December, 2020. Data was collected from tertiary care hospitals in Karachi between October 2021 and November 2022 after approval from the ethics review committee of Ziauddin University, Karachi. Drug utilisation evaluation was done using a structured and validated tool. The treatment protocols were evaluated by comparing against the coronavirus disease-2019 treatment protocol 2020 and the guidelines issued by the Medical Microbiology and Infectious Diseases Society of Pakistan. Second data set comprised of the consumption data (obtained from pharmacies for both inpatients and outpatients) as well as the antimicrobial resistance, (obtained from antibiogram collected from the microbiology departments of the participating hospitals). This data was taken for the period of three years i.e. 2019 (Pre-COVID) to 2021 (Post-first wave of COVID) to establish trends of both consumption and antibiotic resistance. Data was analysed using SPSS 20.
Results: Of the 300 patients, 207(69%) were males and 93(31%) were females. There were 162(54%) adults with mean age 40.06±10.48 years, followed by 120(40%) geriatrics with mean age 70.37±6.94 years 18(6%) paediatrics with mean age 13.5±3.60 years. All patients were given Azithromycin empirically followed by culture sensitivity test in 21% cases only. Comparison with COVID treatment protocols revealed the non-compliance of just 3%. However, in case of Community Acquired Pneumonia (CAP), sinusitis, typhoid and urethritis, comparison with MMIDSP guidelines revealed non-compliance of 95%, 22%, 75% and 100% respectively. Moreover, in 11% of patients, it was administered for conditions not recommended by guidelines. Furthermore, the Antibiogram exhibited percent increase in resistance against azithromycin.
Conclusion: Enhanced consumption and irrational use of azithromycin during the coronavirus disease-2019 pandemic most likely contributed to increase in antimicrobial resistance.
Key Words: Azithromycin, COVID-19, Misuse, Consumption, Resistance.
Comparison of effect of machine muteness to reduce noise anxiety vs regular settings on patient compliance during pan-retinal photocoagulation
Authors: Anam Amna , Malik Irfan Qayyum , Hameed Zeeshan
Published: January 2024

This Quasi Experimental study was conducted at Major Eye Clinic, Gujranwala, from January to December 2022, to study the effect of muting the sound of Argon Laser machine on patient compliance and the pain felt during pan-retinal photocoagulation (PRP). Eighty patients were included in the study with proliferative diabetic retinopathy (PDR), retinal breaks, lattice and myopic fundus degenerations for which PRP was performed. A total of 80 patients were enrolled, who were divided in two groups with 40 patients in each group. Group A patients received muted machine settings, while group B underwent regular PRP. The mean age was 54.6±3.4 years. Sixty-eight (85%) cases were of PDR, 4 (5%) of retinal breaks, 3 (3.75%) of lattice degenerations associated with breaks, and 5 (6.25%) of laser barrage.
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Kepuasan Konsumen Terhadap Pengalihan Pengembalian Donasi Perspektif Etika Bisnis Islam di Minimarket Indomaret
Authors: Septiani Dian , Anwar Nurfiah , Sofyan A. Syathir
Published: January 2024

Studi ini bertujuan untuk mengetahui kepuasan konsumen Indomaret Tanete terhadap pengembalian dana dalam bentuk donasi, serta untuk memeriksa kepatuhan Indomaret terhadap etika bisnis Islam dalam pengembalian uang dalam bentuk donasi. Metode campuran digunakan dalam penelitian ini, yang menggabungkan metode kualitatif dan kuantitatif dalam satu studi. Hasil penelitian menunjukkan bahwa customer yang tidak puas dengan pengembalian dana dalam bentuk donasi merasa bahwa tindakan Indomaret melanggar prinsip-prinsip syariat Islam karena tidak memberikan informasi yang memadai tentang tempat penyaluran donasi, hanya menganjurkan customer untuk mendonasikan dana tersebut. Karyawan Indomaret belum menerapkan sikap adil dan sikap jujur terhadap konsumennya karena tidak terdapat kejelasan dan tidak transparansi dalam pengalihan kembalian dalam bentuk donasi. Dalam hal penerapan sikap kebebasan konsumen memiliki hak atas menerima dan menolak transaksi dalam bentuk donasi di Indomaret. Begitupun dengan sikap tanggung jawab karyawan Indomaret belum menerapkan sikap bertanggungjawab karena tidak adanya bukti struk dan poster tentang penjelasan penyaluran dana donasi.
Eksistensi Green Sukuk Di Indonesia: Analisis Terhadap Fiqih Lingkungan Kh. Ali Yafie
Authors: Adhi Purba Ilyas , Mutafarida Binti
Published: January 2024

Kegiatan manusia merupakan faktor utama terhadap ketidakseimbangan alam, termasuk terjadinya kerusakan lingkungan. Banyak sekali aktivitas ekonomi yang menghasilkan emisi karbon dalam praktiknya sehari-hari. Sehingga muncul konsep green economy untuk membantu mengatasi emisi karbon di bumi. Salah satunya melalui green sukuk yang merupakan intrumen pengembangan perekonomian masyarakat Indonesia melalui jalur investasi saham berbasis syariah. Fiqih lingkungan dapat menjadi arahan bagi masyarakat melaksanakan praktik proyek hijau dalam kegiatan ekonomi. Salah satu tokoh Indonesia pencetus fiqih lingkungan ialah Alm. KH. Ali Yafie. Tujuan penelitian ini untuk menganalisis praktik green sukuk dalam tinjauan fiqih lingkungan KH. Ali Yafie. Metode penelitian merupakan kualitatif deskriptif melalui studi literatur untuk mendapatkan bahan analisis permasalah. Hasil penelitian ini menjelaskan bahwa KH. Ali Yafie berpendapat dalam menciptakan manusia yang sadar akan kelestarian alam, hasus didasarkan pada dua hal yaitu kutub rabbil alamin dan rahmatan lil alamin. Pertama kutub rabbil alamin yang berarti Allah SWT tidak hanya Tuhan manusia, melainkan juga Tuhan seluruh alam. Maka ketika manusia berbuat kerusakan pada alam, sang pemilik alam yaitu Allah tentu akan murka. Kedua kutub rahmatan lil alamin atau keberadaan manusia yang diamanati atas kasih sayang pada alam semesta. Melalui sikap kasih sayang akan menunjukkan kepedulian pada lingkungan.
Kesejahteraan Nelayan Tangkap Dalam Perspektif Ekonomi Islam Di Kecamatan Banggae Kabupaten Majene
Authors: Atirah
Published: January 2024

Kesejahteraan hingga saat ini masih merupakan defenisi semu yang masih terus dipertanyakan kebenarannya. Konsep sejahterah selalu dirasakan berbeda beda dalam tiap kalangan dengan berbagai indicator yang dipertimbangkan setiap individu maupun keluarga, dikarenakan beberapa keadaan konsep kesejahteraan disetiap jenis pekerjaan dan kondisi keluarga dinyatakan berbeda beda. Kesejahteraan untuk masyarakat nelayan, Pembagian tingkatan Nelayan menjadi beberapa tingkatan juga memberikan pemahaman konsep kesejahteraan yang berbeda. penelitian ini adalah penelitian Kualitatif Deskriptif dengan melakukan analisis Kesejahteraan Nelayan Tangkap dilihat dalam perspektif Ekonomi Syariah. Penelitian ini berlokasi di Kec. Banggae Kab. Majene  Kel.Totoli dengan subjek penelitian Pada Nelayan Tangkap . Metode Pengumpulan data dalam penelitian ini adalah Wawancara dan Dokumentasi. Hasil penelitian menunjukkan bahwa nelayan merupakan anggota dari kapal bodi yang setiap berlayar mencari ikan mereka akan beranggotakan beberapa orang dan akan dimodali oleh seorang yang dinamakan Punggawa. Kesejahteran spiritual, kesejahteraan materil dan kesejahteraan moral dilihat dari aktivitas nelayan dalam menjalankan profesinya serta kerja sama yang ditunjukkan hingga pembagian hasil melaut hingga menanggapi dan beradaptasi dengan kondisi dan keadaan ketika tidak dapat turun melaut dikarenakan cuaca.