bluuebunny/crossref_metadata_2025 huggingface dataset:
CITY INFORMATION MODELING (CIM) COMO FERRAMENTA DE APOIO AO PLANEJAMENTO URBANO COM FOCO EM CONFORTO TÉRMICOS
Authors: Borges Marcos Martins , Rodrigues Ana Carolina Caldas , Oliveira Gabriella Dias de , Guimarães Tuanny Cristinny da Cunha
Published: November 2023

Este artigo discute a necessidade de um planejamento urbano que prioriza a qualidade do ambiente construído e o conforto dos indivíduos, tendo em vista as mudanças climáticas e a necessidade de estratégias de mitigação do efeito destas. A partir do entendimento de que o espaço urbano se caracteriza por um organismo complexo, definido por diversas dimensões, faz-se necessário  a adoção de ferramentas que possibilitem tratar suas especificidades para o alcance de um planejamento urbano eficiente e que proporcione um ambiente confortável termicamente. Sendo assim,  o presente artigo tem por objetivo discutir o uso da tecnologia City Information Modeling (CIM) como ferramenta de apoio ao desenho urbano com foco no conforto térmico. Para esta pesquisa de caráter exploratório foi adotada como processo metodológico a revisão bibliográfica documental dos temas tocantes ao interesse desta pesquisa e apresentação de um estudo de caso. O principal resultado desta pesquisa se concentra no papel da ferramenta CIM como facilitadora na gestão eficiente dos parâmetros e na atuação conjunta dos diversos setores que atuam no planejamento urbano. Este artigo tem como principal contribuição reforçar o papel dos profissionais atuantes no planejamento urbano e afirmar a importância de ferramentas que melhorem a gestão do ambiente construído.
ESTUDOS DAS QUADRAS E LOTES EM CUIABÁ NO SÉCULO XVIII
Authors: Oliveira Vitória Roberta Miguel de , Galdino Yara da Silva Nogueira
Published: November 2023

O artigo apresentado foi desenvolvido no projeto de pesquisa Casa Cuiabana: Arquitetura Residencial em Cuiabá durante o Período Colonial. Visando analisar a morfologia urbana de quadras e lotes do século XVIII, relacionando-a à tradição das cidades de origem portuguesa. Na análise da forma urbana, admitisse que a cidade resulta de múltiplas influências, como; acontecimentos históricos, contexto socioeconômico, características geográficas e demográficas. Esses elementos marcam a forma urbana, sobrepondo-se ao longo do tempo, registrando cada momento histórico. Registros que podem ser entendidos como palimpsestos, conforme Ozo (2009, apud Costa & Netto, 2017) representa camadas temporais sobrepostas, determinadas por mudanças econômicas e culturais, resultando em alterações no espaço urbano, revelando diferentes fases históricas da cidade.  O centro histórico de Cuiabá inicia seu período de formação no século XVIII, passando por mudanças em seu espaço urbano. Segundo Rossi (1995) o traçado seria um dos fatos urbanos mais resistentes às transformações, constituindo muitas vezes em permanências de períodos históricos anteriores.  Desta forma, esta pesquisa visou identificar as características dos quarteirões e lotes coloniais, sintetizando tipologias que pudessem ser associadas às características da tradição urbanística portuguesa e evolução urbana do território. Baseando-se na análise da planta de Cuiabá de 1786, e estudos de Teixeira (2012) sobre a formação do lote urbano na cidade de tradição portuguesa, identificou-se cinco tipologias de quarteirões. Cada um desses tipos apresenta características específicas, compondo o tecido urbano da Cuiabá setecentista.
EDIFÍCIOS HISTÓRICOS E PAISAGEM NOTURNA: ILUMINAÇÃO E MEMÓRIA VISUAL URBANA
Authors: Silva Sara Dantas da , Gallo Douglas
Published: November 2023

O presente artigo explora duas paisagens urbanas distintas, separadas pelo crepúsculo, uma diurna (definida pela iluminação natural) e outra noturna (determinada pela iluminação artificial). O objetivo foi analisar e caracterizar as paisagens urbanas e ambiências características de cada período. A iluminação urbana - de fachada e de monumentos - contribui diretamente na ampliação do tempo de vivência urbana, gerando ambiências e possibilidades de sociabilidades que prolongam a vida urbana para o período noturno. Foi realizada uma revisão bibliográfica e uma análise espacial por meio de registros fotográficos, anotações e descrição da iluminação e ambiência de elementos edificados históricos da região central da cidade de São Paulo/SP. Os registros foram realizados no mesmo dia, em momentos distintos, à luz do dia e sob iluminação artificial no período noturno. A análise da ambiência e da paisagem urbana buscou compreender sua relação com a memória visual e potencialidades dos elementos iconográficos do ambiente urbano, configuradores de ambiências, paisagens e memórias coletivas.
A RUA, A PRAÇA, O LABIRINTO
Authors: Lippi Giovana Diniz Giosa , Guatelli Igor
Published: November 2023

E se, ao pensar em infraestruturas urbanas, deixássemos de restringir seu entendimento mais direto às obras de grande porte - viadutos, aeroportos e ferrovias – e pensássemos em outros entrelaçamentos necessários à qualidade de vida urbana? Seriam também, espaços infra estruturais, aqueles que provocam coletividades e possibilitam a invenção cotidiana? A partir de cruzamentos entre o projeto do Sesc Pompeia, da arquiteta Lina Bo Bardi, e da instalação artística Leviathan realizada por Anish Kapoor no Grand Palais de Paris, pretende-se discutir como esses projetos possibilitam novas, e inesperadas, formas de explorar e interagir com o espaço, agindo assim, como elementos infra estruturais. Constantemente em atualização, Sesc Pompeia e Grand Palais, cada um em seu contexto histórico, são espaços com a capacidade de absorver exterioridades e reinventar-se, como uma espécie de palimpsesto urbano. São arquiteturas que agem como suportes para contaminação externas, são receptáculos, espaços gestacionais, à espera do porvir. Espaços flexíveis, que se esquivam de logicas engessadas e dominantes, tornam-se então, capazes de responder a seu tempo e assimilar às exterioridades sem assumir uma identidade única. Obras dotadas de uma espessura simbólica, mas que estão em constante atualização, contaminadas pelo presente, mantendo rastros do passado.
METODOLOGIAS DE ANÁLISE URBANA: DAS PRIMEIRAS CRÍTICAS DO URBANISMO MODERNO AOS DIAS ATUAIS
Authors: Tasca Luciane , Campello Mauro Santoro , Barcellos Bernardo Lima Pinto , Cesar Annelise Mendonça , Alves Patricia Nogueira , Avelar Pedro Loures
Published: November 2023

Com a finalidade de realizar uma revisão bibliográfica das metodologias de análise urbana, a partir das primeiras críticas ao urbanismo moderno até os dias atuais, objetiva-se refletir sobre questões urbanas, com foco nos autores que atuavam no campo do urbanismo e da arquitetura nos anos 60 e naqueles autores que retomaram as discussões sobre os estudos urbanos posteriormente. A intenção é revisitar os mestres que empolgaram as décadas de 60, 70 e 80 do século XX e os que buscaram, posteriormente, cobrir o abismo entre planejamento urbano, projeto de arquitetura e urbanismo e metodologias de análise da cidade. A temática apresenta grande relevância acadêmica, tendo em vista a dificuldade em encontrar materiais didáticos que deem suporte aos estudos sobre as transformações das cidades, entendendo-as, para propor mudanças sustentáveis. Espera-se contribuir para o estudo das cidades, com este material que fornece uma leitura, conforme elucida a arquiteta e crítica Marina Waisman que busca a interpretação das questões que envolvem a análise urbana no período selecionado, sistematizando-a em uma linha do tempo que sobrepõe categorias de análise e considera o contexto no qual estão inseridas. Tal trabalho fomenta discussões e reflexões sobre o urbanismo, que acarreta também no pensar a cidade em que vivemos atualmente, visto que, diferentemente da historiografia geral, que tem por objeto de estudo algo que deixou de existir no tempo, a historiografia da arquitetura e do urbanismo, tem por objeto algo existente no presente.
HABITAÇÃO SOCIAL COMO PILAR DO ESTADO DE BEM-ESTAR SOCIAL: DIFERENÇAS SOCIOTERRITORIAIS ENTRE BRASIL E SUÉCIA
Authors: Maroso Caio Barbato , Luz Vera Santana
Published: November 2023

O objetivo deste artigo é apresentar o estudo de caso de dois conjuntos habitacionais, um no Brasil e um na Suécia, e discutir as diferenças na organização no território e a consequente habitabilidade de programas habitacionais moldados pelas duas realidades. Adotamos duas categorias diferentes de estados de bem-estar social. Na Suécia, socialdemocrata; no Brasil, meritocrático-clientelista. A abordagem da habitação social como pilar do estado de bem--estar social e a comparação com um país social-democrata são incomuns nesse campo de pesquisa, no Brasil, mas não em pesquisas estrangeiras. A metodologia de análise dos casos foi desenvolvida com base em quatro categorias que permitem comparações a partir das diferenças. O principal resultado é que, quando comparados à realidade brasileira, o ambiente urbano e a habitabilidade tendem a ser melhores na Suécia, onde a habitação pública é construída com base na lógica social-democrata de política pública, como pilar do estado de bem-estar social.
GARANTINDO A SEGURANÇA HÍDRICA COMO UM DIREITO HUMANO FUNDAMENTAL: ANÁLISE DOS MARCOS REGULATÓRIOS INTERNACIONAIS E NACIONAIS
Authors: Monteiro Ari Machado , Costa Carine Zachariadhes Pinto R. da , Pereira Jaildo Santos
Published: November 2023

Este estudo se concentra em aprofundar a compreensão da segurança hídrica como um direito humano essencial, analisando os desafios globais e nacionais ligados ao acesso à água potável e saneamento. Através de uma abordagem teórica e analítica, explora marcos internacionais e nacionais relacionados à segurança hídrica, incluindo fatores geopolíticos e o impacto das mudanças climáticas na disponibilidade de água. Sua originalidade e relevância residem em preencher uma lacuna teórica ao conectar segurança hídrica e direitos humanos, especialmente diante das crescentes pressões demográficas e ambientais. Ao identificar desafios como escassez hídrica, mudanças climáticas, desigualdades e poluição, destaca a importância de estratégias adaptativas e colaborativas para enfrentar essas questões. Contribuindo tanto teórica quanto metodologicamente, enriquece a compreensão ao vincular segurança hídrica e direitos humanos, sublinhando a relevância da gestão sustentável e políticas coordenadas. Por meio de uma abordagem analítica, ilustra a complexa interação entre fatores políticos, ambientais e sociais. As implicações sociais e ambientais são significativas, pois enfatiza a necessidade de ações concretas e políticas coordenadas para garantir um acesso equitativo à água e saneamento, promovendo dignidade humana e bem-estar. Além disso, contribui para a preservação dos recursos hídricos, enfrentando diretamente os desafios globais da sustentabilidade. Este estudo oferece insights valiosos sobre a interseção entre segurança hídrica, direitos humanos e desafios ambientais, ressaltando a importância de abordagens colaborativas e políticas sustentáveis. Essas abordagens são vitais para garantir um futuro em que o acesso universal à água limpa e segura esteja assegurado, promovendo o bem-estar e a sobrevivência de toda a humanidade.
Nurturing academic leadership: A quest for the ideal academic leadership style for Maldives higher education
Authors: Waheeda Aishath , Vasudevan Asokan , Hai Sam Toong , Balakrishnan Rajani
Published: November 2023

Higher education leadership is an understudied area, especially at the departmental or faculty level. The current study explored preferred academic leadership styles as perceived by academic deans and their lecturers in Maldivian Higher Education Institutes (HEIs). A sequential explanatory mixed method design informed by post-positivist techniques was used in this study. In the first phase, the survey method was used to directly reach many respondents, administer the instruments and to collect the required data. from deans (N=20) and lecturers (N=170) from nine different HEIs. SPSS (Statistical Package for the Social Sciences) version 23 was used to analyze the data using descriptive statistics and inferential statistics such as means, percentages, standard deviations, independent sample t-test and Pearson correlation coefficients. In the second phase, a qualitative approach was used to explain, validate and to triangulate the quantitative findings. This phase used semi-structured interviews for purposively selected deans (N=5) and lecturers (N=16) from seven different HEIs. The interview transcripts were thematically analyzed and coded using the template analysis method.  The most preferred academic leadership styles in Maldivian HEIs were found to be transformational, distributed, and transactional leadership styles, respectively. To enhance academic leadership in HEIs in the Maldives, this study recommends academic leaders to use transformative and distributive leadership behaviors, which would also help HEIs in the skill development of academic deans.
Comparative efficacy of different thicknesses of soft and hard splints in reducing clinical symptoms in patients with temporomandibular disorders
Authors: Madani Azamsadat , Mirmortazav Amirtaher , Bagheri Iraj Mohammad
Published: November 2023

Introduction: The effectiveness of two soft and hard splint thicknesses in reducing temporomandibular joint (TMJ) pain and dysfunction was compared.
Materials and Methods: Sixty patients with TMJ pain and dysfunction were randomly assigned to four groups (n=15); the patients treated with hard occlusal splints of 1 and 3mm thicknesses were assigned to Groups A and B, respectively, and those treated with soft occlusal splints of 1 and 3mm thicknesses were assigned to Groups C and D, respectively. Maximum mouth opening (MMO) and the severity of pain based on the visual analog scale (VAS) were assessed before treatment and after 7, 30 and 90 days.
Results: After both 7 and 30 days, no significant differences were found between the groups for any variable (P>0.05). However, Group C had a significantly lower MMO compared to Groups A and B after 90 days (P=0.001). Additionally, and in relation to masticatory muscle pain, Group C had a significantly higher VAS score than other groups (P<0.05). The VAS score for TMJ pain at rest was also significantly higher in Group C compared to Groups A and B (P<0.05).
Conclusion: A 3-mm hard occlusal splint seems to be the best treatment to reduce pain and dysfunction of the TMJ.
Prasa w życiu polskich zesłańców – Syberia Wschodnia w połowie XIX w.
Authors: Nowiński Franciszek
Published: November 2023

Несмотря на огромное расстояние, отделяющее Восточную Сибирь от Западной Европы и даже от европейской части России, туда проникала как столичная российская пресса, так и западноевропейские периодические издания. Середина XIX в. была особым периодом в истории этого региона империи. С 1847 г. иркутским генерал-губернатором был считавшийся либералом ген. Николай Муравьёв. Его социально-политические амбиции способствовали подписке и чтению газет. Читатели имели доступ даже к материалам, издаваемым Александром Герценом в Лондоне. Количество доступных в Иркутске периодических изданий было впечатляющим, назовем здесь только некоторые из них: „Journal des Débats”, „Le Siècle”, „La Presse”,
„La Mode”, „La Semaine”, „I’Illustration”, „Journal de Francfort”, „Revue des deux Mondes”, „Illustrierte Zeitung”, „Allgemeine Zeitung”, „Indépendance Belge”,
„Dorf-Barbier” (Dorfbarbier), „Galligani’s Messenger”. Более того, здесь можно было купить «Санкт-Петербургские ведомости» не только на русском, но и на французском языках, а также издания „Biblioteka Warszawska”, „Gazeta Warszawska”. Круг читателей западноевропейской прессы был ограничен людьми, владеющими иностранными языками, т.е. декабристами и польскими ссыльными (хотя и не всеми). Наибольшей популярностью пользовались издания на французском языке, меньшим был спрос на англоязычные газеты и журналы. Для поляков западная пресса была источником информации о Весне народов в Западной Европе и на польских землях. Они с нетерпением читали донесения о краковском восстании 1846 г., о протекании революционного движения во Франции и венгерском восстании 1849 г. И хотя заграничные новости контролировались российской цензурой и были доступны читателям в сокращенной форме, они все равно были полнее и интереснее того, что печаталось в королевской (польской) или же российской прессе. Богатым источником сведений о реакциях польских ссыльных и декабристов является дневник польского ссыльного Юлиана Сабиньского, который с 1843 г. жил в Иркутске. Из финансовых соображений практиковалась коллективная подписка. Часто подписчики сообщали друг другу, кто на что подписывается, с тем, чтобы потом обменяться полученными изданиями. Например, декабристы делились впечатлениями от прочитанного с поляками, а ссыльные из окрестностей Иркутска – с ссыльными из Забайкалья. Они также обменивались мнениями по поводу дальнейшего развития событий. Таким образом удавалось – хотя и с небольшим отрывом во времени – следить за актуальной социально-политической ситуацией в Европе того времени.
Przemiany w położeniu kobiet w Niemczech Zachodnich po II wojnie światowej – kontynuacje i przełomy
Authors: Jedynakiewicz-Mróz Katarzyna
Published: November 2023

The article presents the main changes of the situation of women in Western Germany after the Second World War. The cosiderations are based on the femal diaries from this period, as well as on the specialist literature.
The first part of the text shows professional and educational activity of women in Germany in the years 1945–1949 and the femal part in the restoring of the country from the war damages. The second part of the article presents the occurence of the return to the traditional patterns of feminity in Federal Republic of Germany in time of the Christian Democracy rules (1949–1965). The third part of the cosiderations shows the effects of „the 1968 Revolution” for the women’s situation in Western Germany in time of the domination of the Social Democrats in this country (1969–1982). The fourth part of the text presents the increase of the real position of women in Federal Republic of Germany in the Eighties, in the context of the development of the civil society in West Germany.
Immobilization Strategies for L-Asparaginase from Ganoderma australe GPC191: Impact on Enzyme Activity, Stability, and Reusability
Authors: Chakraborty Meghna , Shivakumar Srividya
Published: November 2023

L-asparaginase has garnered significant attention for its potential therapeutic applications in cancer treatment, as well as its role in mitigating acrylamide in the food industry. However, the widespread implementation of free L-asparaginase in industrial processes has faced substantial obstacles, primarily attributed to issues such as reduced stability, high production costs, and limited recyclability. In order to address these challenges and fully unleash the capabilities of L-asparaginase, the current investigation was centered on the exploration of L-asparaginase immobilization derived from Ganoderma australe GPC191. The various immobilization matrices were assessed, including gelatin, agarose, agar, and combinations thereof with sodium alginate, carboxymethyl cellulose, and calcium phosphate. These matrices were evaluated based on critical parameters such as enzyme activity after immobilization, loading efficiency, recyclability, and storage stability. Among the diverse matrices considered, the alginate-gelatin-calcium phosphate capsules emerged as the best, exhibiting remarkable characteristics such as an enzyme activity of immobilized L-asparaginase at 60.43 U/mL, an impressive loading efficiency of 94.82%, sustained recyclability with 51% stability even after 16 cycles, and a storage efficiency only reducing to 27% at six months. These outstanding attributes position them as a promising choice for industrial applications. The encouraging outcomes of this investigation could be further refined through research into the effects of altering the concentrations of matrix components, shedding light on how these adjustments influence enzyme properties and their interactions with the external environment.
Akibat Hukum Pelaku Usaha Terhadap Produk Pangan Yang Tidak Bersertifikasi Halal
Authors: Citra Andita Nara , Widyanti Ikarini Dani
Published: November 2023

Abstract :

Every pangan product made in Indonesia must have a halal certification before being sold to the general public. Halal certification is accomplished by applying a halal label to products that are produced and by including a halal declaration in the packaging. This action is intended to encourage the general population who do not consume unhealthy food to do so (haram). It is stated in Pasal 4 Undang-Undang No. 33 Tahun 2014 about Jaminan Produk Halal that products that are imported into, are manufactured in, and are distributed in Indonesia must be certified as halal. On the other hand, there are a lot of foods that are sold in stores that lack halal certification. The purpose of this study is to understand how the hukum that was expressed by the owner of a business selling pangan without a certification that it was permissible under Islamic and positive law.

Keywords : owner of a business; food product; certified halal.
Diastereoselective synthesis of a novel cyclic derivative based on 2,3-indolinedione
Authors: Sucman Natalia
Published: November 2023

Generally, organic synthesis is renowned for its predictability in determining results. Nevertheless, there are situations where instead of the expected products, unexpected compounds with unique structures may arise. This report is a presentation of one such remarkable cyclic compound with four chiral centres prepared by diastereoselective dimerization of Morita-Baylis-Hillman (MBH) adducts of acrylonitrile to 5-chloro-indole-2,3dione. MBH adducts are very popular in organic chemistry. They are synthesized by the addition of an activated alkene and a carbon electrophile in the presence of a nucleophilic catalyst, such as a tertiary amine or phosphine. The product is densely functionalized, joining the alkene at the α-position to a reduced form of the electrophile with a new carbon-carbon bond. In cases where indol-2,3-dione acts as an electrophile in such reactions, literature examples are found only with N-substituted isatins [1-3]. We attempted to carry out this reaction using unsubstituted 5-chloroindol-2,3-dione. As a result, a series of products were isolated, among which several similar compounds of particular interest were observed, with NMR spectra showing a double set of signals. The overall yield of these compounds was insignificant, and their chromatographic separation proved to be very labour-intensive. In order to enhance the stereo-selectivity of the reaction and consequently increase the yield of the desired compound, conditions were optimized in which the corresponding MBH adduct was used as the starting substrate. In the presence of DABCO and acetic ether as catalysts, primarily, a single substance with an unusual cyclic structure was formed (Figure 1).Figure 1. The synthesis of cyclic dimer. NMR spectra were consistent with the proposed structure. To confirm it, X-ray structural analysis was conducted.
Targeting the bioactive dihydropyrimidines by ecofriendly procedure of biginelli reaction: study case of monastrol
Authors: Verdes Anastasia , Gorincioi Elena , Lupascu Lucian , Duca Gheorghe , Macaev Fliur
Published: November 2023

Biologically active compounds decorated with dihydropyridine moiety are counted amongst the numerous broad-spectrum therapeutic agents that explain the increasing role of this scaffold in rational drug design [1]. The Biginelli reaction is a multicomponent reaction of aldehyde, (thio)urea, and ß-ketoester, involving Mannich reaction in the first step, which produces multifunctionalized 3,4-dihydropyrimidin-2-(1H)-ones and related heterocyclic compounds [2]. The attractiveness of this acid-catalyzed one-pot condensation reaction lies in the simplicity of grafting the substituent into the structure of the products, which can later be transformed into different functional groups that are required for subsequent syntheses. Monastrol, the most representative Biginelli adduct in anticancer drug development, proved to be a cell permeable molecule whose mechanism of action on cancer cells involves the selective inhibition of the motility of the mitotic motor enzyme kinesin Eg5 [3]. Thus the remarkable therapeutic and pharmacological potential of it maintains expressive interest of chemists, some green synthesis approaches being recently reported, as well [4,5]. In continuation of our research line [6], we herein report on a facile ecofriendly synthesis of (±)-M, based on the use of oxalic acid (20mol/%) as green catalyst instead of toxic Lewis acids. The proposed procedure also offers the advantage of shortening the reaction time twice, in comparison with the classic reaction, producing the racemic target compound in 60% yield, m.p. 182-184⁰C (crystallized from ethyl acetate), rep. 182-184⁰C [4,5]. The prepared (±)-monastrol has shown antifungal activity against Candida albicans and Saccharromyces cerevisiae at concentrations 8 times lower than reference antifungal agent Nystatin.
Analytical studies on the fractionation products from lavender extracts
Authors: Organ Adina , Jian Mariana , Cobzac Vitalie , Birca Natalia , Cotelea Tamara , Cirimpei Octavian , Kulcitki Veaceslav , Nacu Viorel
Published: November 2023

Lavender (Lavandula angustifolia) is a widespread aromatic plant exploited globally for essential oil production. It is known that the remaining wastes after industrial processing are rich in secondary metabolites with relevant biological activities [1]. In particular, triterpenic acids have recently attracted the interest of scientific community because of their broad activity spectrum which makes them very attractive for the use in cosmetics and healthcare products as functional compounds. The aim of this study was isolation and analytical studies on different fractions obtained from Lavandula angustifolia ethanolic extracts. The vegetal plant material represented wastes generated on the extraction of essential oil at industrial scale. The obtained integral extracts were mixed with different organic solvents of different polarity in acid and basic medium, thus obtaining a series of fractions with different content of secondary metabolites. The fractions with a high content of triterpenic acids were selected by using thin layer chromatography. The analytical experiments included determination of total polyphenols with the Folin-Ciocâlteu reagent, quantitative determination of flavonoids, FRAP reducing capacity test and qNMR determination of oleanolic, ursolic, pomolic and rosmarinic acids. According to the obtained results fractions showing higher total polyphenols (495.59 mg EGA/g of extract) were also rich in flavonoids (343.01 mg catechin equivalent/g of extract) demonstrating relevant reducing capacity (386.67 mg EGA/g of extract) and high rosmarinic acid content (cca. 250 mg/g of extract). The triterpenic acids have been found to predominate in less polar fractions.
The phenomenon of “pedagogical support” in current pedagogical research
Authors: Abdalina Larisa V. , Mou Shuzhan
Published: November 2023

Importance. In modern educational conditions the question of ensuring the effectiveness of all educational process participants pedagogical interaction arises frequently. The teacher is increasingly faced with the task of creating conditions in which he would be able to fully meet the educational needs of students. The solution to the problem is realized through pedagogical support – an effective means of implementing the necessary measures of pedagogical influence to create the best interaction of all educational process subjects. Nowadays pedagogical science has accumulated quite a lot of theoretical material on pedagogical support, and numerous studies of the effectiveness of the phenomenon is conducted. The purpose of the research is to consider the main approaches to the studied phenomenon, systematization of scientific material on the research topic.
Research Methods. The research is conducted by analyzing scientific publications with pedagogical support subject.
Results and Discussion. The history of the studied phenomenon formation is given, its gradual development and allocation into an independent field of research is traced. Various approaches and points of view to the interpretation of the concept are analyzed. On the given basis the author’s definition based on the individual and system approach to its interpretation is proposed. The essential characteristics and specificity of pedagogical support, the main stages of its realization are defined, the components of pedagogical support are considered. The stages are reduced to the main three: diagnostics, technology and evaluation of its effectiveness. Pedagogical conditions that contribute to the successful realization of pedagogical support are presented. The necessity of identifying general and universal criteria for the effectiveness of pedagogical support, which should evaluate not the accompanied process, namely, pedagogical support as a method or technology. Such criteria include the dynamics of the accompanied process, its qualitative changes and reduction of the time of changes.
Conclusion. It is concluded that the phenomenon under study is a complex and interdisciplinary concept that requires methodological elaboration and further research. Practical application of the obtained theoretical results allows to develop on given basis a comprehensive theory of pedagogical support, applied in practice in work with different categories of students.
A sight translation contest as a tool to identify common student difficulties in translating economics texts
Authors: Stepanova Maria M. , Lukyanova Valentina S.
Published: November 2023

Relevance. Sight translation of business documents and news is widely used in today’s business communication. Unfortunately, this type of translation is often overlooked in university curricula. Sight translation is seen as a mere step towards simultaneous interpretation and is skipped. However, it is this type of translation that we need to focus on, as a large number of translation errors are reported in real-life situations.
Materials and Methods. We analyzed and aggregated available data from open sources: university website posts about the student contest, surveys of contestants, interviews with organizers and judges, qualitative and quantitative analysis of the most common difficulties (emotional, cognitive and motor challenges) and presented our experience with the organization of the student translation contest at the Moscow Institute of International Relations, Oditsovo Campus.
Results and Discussion. We categorized the typical errors made by the participants. The errors can be purely linguistic, caused by insufficient language skills, and extra-linguistic (emotional, cognitive and motor). The most important reasons for making errors are low stress resistance, lack of attention, insufficient understanding of the subject matter and, as a consequence, poor understanding of the context, insufficient knowledge of special terminology, and missing intra-sentence references.
Conclusion. The research shows that a sight translation contest is an effective tool for identifying and preventing common difficulties that students may have in translating specialized texts.
E-learning dictionary of business English idioms designing experience
Authors: Rogova Margarita Y. , Sorokina Elvira A.
Published: November 2023

Importance. Presented the main results of creating an educational dictionary taking into account modern linguodidactic requirements to the process of designing reference aids. The main content of the research is related to the presentation of the process of creating an electronic training dictionary of phraseologisms related to business and economics. The novelty of the research lies in the rapid development of computer lexicography, which makes it necessary to use training dictionaries in teaching a foreign language for professional purposes.
Materials and Methods. The study dictionaries of business English, textbooks on teaching English of business and economics sphere, as well as scientific literature and Internet sources are presented. Theoretical analysis of scientific literature on the research topic, the method of solid sampling, modeling and design methods, as well as elements of statistical analysis and pedagogical experiment are used as the main methods.
Results and Discussion. During the experiment, the indicators improved more than twice, which suggests that the training dictionary helps students to memorize phraseological units better. Results obtained in the research seem to make a certain contribution to the solution of an important problem of formation of terminological competence of students of economic specialties, to the development of digital educational lexicography.
Conclusion. The practical significance of the research lies in the possibility of using the developed lexicographic resource in the process of teaching students English in the sphere of business communication, as well as in the possibility of using the developed approaches to dictionary design in the practical activity of compiling electronic dictionaries of English for special (professional) purposes.
The use of mind maps for teaching vocabulary and developing oral speech at a military university
Authors: Varushkina Anastasiya V. , Potaluy Valeriya V. , Shirshikova Ekaterina A.
Published: November 2023

Importance. The current situation requires new approaches to help students acquire the necessary skills of professional communication. The development of visual, cognitive means of training military specialists, which includes the technology of mind maps, seems to be relevant.
Materials and Methods. The theoretical and methodological basis of the research includes the studies of V.F. Shatalov, E.V. Budaev, Т. Buzan, H. Muller, A.R. Kamaleeva, O.A. Kondratenko and others.
Results and Discussion. The current paper has analyzed the distinctive features of mind maps: the presentation of information using non-linear schemes based on the principle of associative thinking. The advantages of using mind maps in the process of teaching oral communication are revealed: increased learners' attention and cognitive interest; ensuring a deeper understanding of the educational material; rationalization of the educational process; development of self-control skills; development of intellectual and creative potential. The types and variants of using mind maps for the study of terminological vocabulary, which seems to be the basis for the production of both dialogic and monologue professionally oriented speech, are considered. The stages of dealing with mental cards for teaching vocabulary and developing oral speech in a military university are formulated.
Conclusion. The results of the study have shown that the use of the technology of mind maps makes it possible to gain lexical material as efficiently as possible, extract key information from the text and present it in the form of a speech. It seems that the considered cognitive-visual approach makes it possible to effectively solve the problems of foreign language teaching at a military university.
Memory formation about World War I through British veterans’ activities and the historical policy of Great Britain in the 1930s
Authors: Inkin Victor V.
Published: November 2023

Importance. The scientific problem lies in the World War I historical memory’s formation’s features’ study. The purpose of the research is to reveal what was the ratio of the state’s and veterans’ influence in the narratives’ formation of World War I historical memory in the Great Britain in the 1930s.
Research Methods. The historical policy of the British government in the field of the memory about World War I was studied by a historical and systematic approach for consideration as one of the instruments of influence on the Great Britain’s society. The activity of veteran organizations and individual front-line soldiers during the 1930s was analyzed, whose protest against the state narrative of historical memory after the “Great Depression” began to fade by 1939.
Results and Discussion. On the basis of the materials of the British press of the 1930s, as well as the involvement of additional sources, narratives about World War I were illustrated, which gradually changed in the 1930s. The ideology and activities of the state in the field of historical policy actively from 1932–1933 displaced negative ideas about the war, suppressed anti-war movements and pacifist sentiments in British society. The strengthening of the state’s influence on the British Legion testified to its subordination to the official agenda, which allowed the ruling circles to use veterans in the implementation of domestic and foreign policy (to develop international contacts, influence public opinion).
Conclusion. The value of the research lies in the introduction into scientific circulation of the materials of the British press as historical sources that allow us to trace the gradual weakening of the role of veterans’ organizations in the field of memory about World War I by the middle of 1930s, and the strengthening of the influence of the state in this regard. The correlation of official and public (veteran) narratives in historical memory is shown.
The problem of “settler colonialism” in the history of Palestine: modern interpretations
Authors: Penkov Vladimir F. , Romanov Vladimir V.
Published: November 2023

Abstract. A review is given of the new monograph by Palestinian-Israeli sociologist Areej Sabbah-Khoury “The Colonization of Palestine: The Zionist Left and the Making of the Palestinian Nakba” (Stanford University Press, 2023). This publication is a comprehensive historical and sociological study that examines the problem of Palestinians displacement from their lands by Israeli settlers in the first half of the 20th century. The author of monograph shares a critical approach to the official point of view in Israeli historiography on the Palestinian problem. Reviewers point to the innovative characteristics of the A. Sabbah-Khoury’s research, emphasizing her active use of interdisciplinary historical and sociological methodology. The researcher’s attention is focused on the historical relationship between the ideology of the left Zionists and the practice of seizing Palestinian lands. A. Sabbah-Khoury managed to collect rich empirical material: materials from eight Israeli archives, including the archive collections of three kibbutzim. Areej Sabbah-Khouri’s research, as shown in the review, demonstrated the importance of analyzing those aspects of settler colonialism that were practically not taken into account in official Israeli historiography (the duration of the Zionist colonial project, the features of social interaction between settlers and the local population, the role of coercion in the struggle for control over land).
Did I say ‘pup’ or ‘pub’?
Authors: Souza Hanna Kivistö de , Lintunen Pekka
Published: November 2023

Language users possess knowledge about the second language (L2) phonological system and their own L2 pronunciation, known as phonological awareness and phonological self-awareness, respectively. Higher awareness about the L2 phonology has been shown to be beneficial for L2 pronunciation accuracy (e.g. Kennedy & Trofimovich, 2010), making it relevant to know which features L2 learners are able to notice and how the L2 phonology can be brought into the learners’ attention better. The aim of the paper is to examine language learners’ awareness about their own pronunciation by investigating which L2 segmental features are noticed, how one’s intelligibility is perceived and how participants view their phonological self-awareness abilities. 33 L1 Finnish learners of English enrolled in an English phonetics and phonology course recorded a speech sample and later listened to it by noting down the perceived pronunciation deviations on selected features. The participants also answered a phonological self-awareness questionnaire. The results indicate that the learners noticed segmental deviations in their productions, mainly in relation to consonantal voicing and vowel duration. The participants also perceived themselves as highly intelligible and reported it to be easy to notice the gap in their pronunciation, to identify pronunciation deviations in other speakers’ speech and to identify Finnish-accented English. Nevertheless, the overall verbalization of noticing was scarce and the participants manifested difficulties in explaining the noticed phenomena. The discussion relates the phonological self-awareness findings to pedagogical applications.
THE EFFECT OF ABDOMINAL MASSAGE AND KUNYIT ASAM HERBS TO REDUCE PRIMARY MENSTRUAL PAIN (DYSMENORRHEA)
Authors: Sumardiko Dwi Setiani , Maulida Rizki Roswandi Alyaa’ , Purwitasari Neny , Hamsidi Rini
Published: November 2023

Background: Menstrual pain (dysmenorrhea) is a cramp in the lower abdomen that occurs during menstruation, while menstrual pain that is experienced without any abnormality in the reproductive organ is called primary dysmenorrhea. Primary dysmenorrhea case experienced by the patient is complaints of pain in the lower part, sometimes spreading to the waist and feeling like pressure or squeezing which occurs within 1-2 days of menstruation. Purpose: Determine the effect of abdominal massage therapy and tamarind turmeric herbs on reducing primary dysmenorrhea. Case analysis: A case study for treating menstrual pain using abdominal massage and herbal methods. Abdominal massage therapy is performed on the abdominal area and herbal therapy is given to the patient, namely herbal turmeric (Curcuma longa Linn.) and tamarind fruit which have analgesic, antipyretic, and anti-inflammatory effects. Result: Turmeric and tamarind contain active compounds curcumin and anthocyanin which work together to inhibit cyclooxygenase (COX) reactions so that they can inhibit or reduce inflammation and uterine contractions which cause menstrual pain. The treatment for primary dysmenorrhea is abdominal massage therapy 14 times, once every 2 days for 30 days. Meanwhile, tamarind turmeric herbal therapy is given 2 times a day for 7 days before menstruation and the first 3 days during menstruation with a combination dose of 10 grams of turmeric rhizome and 5 grams of tamarind fruit. Conclusion: Abdominal massage therapy and tamarind turmeric herbs affect reducing menstrual pain in the case of primary dysmenorrhea.
MOLECULAR CHARACTERIZATION OF CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE AT A TERTIARY CARE LABORATORY IN KERALA, INDIA
Authors: C. Senan Swapna , Paul Jacob Jithu , Bhai Ramani
Published: November 2023

Background: Isolates of Klebsiella pneumoniae resistant to Carbapenem appears to be most commonly transmitted by hospitalized patients. This may cause infections which lead to mortality. Therefore, studies on molecular level will help to gain more information and be able to know their cross-transmission and resistance mechanisms among these isolates showing resistance. Purpose: Investigate the molecular characterization of carbapenem-resistant Klebsiella pneumoniae isolates from various clinical samples. Klebsiella pneumoniae are aerobic and Gram-negative bacilli found in the gastrointestinal tract of humans and other animals and also as saprophytes in soil. Method: In this study, 401 bacteria of Klebsiella isolates were taken from various clinical samples according to standard protocol. Carbapenem-resistant genes of Klebsiella pneumoniae (CRK) isolates were detected using multiplex polymerase chain reaction (PCR). Result: The twelve isolates resistant to carbapenem were confirmed phenotypically and were confirmed using a multiplex Polymerase Chain Reaction. Conclusion: The present study concluded that identification of Carbapenem-resistant genes of Klebsiella pneumoniae (KPC) could help find out the routes of dissemination of the species and may control its spread within the hospital premises.
Combined anti-PD-1 and anti-CTLA-4 Treatment in Stage IV Melanoma Patients: Bicentric Analysis of Real-world Data
Authors: Silași Alexandru Dorin Adrian , Sievert Anna Carolin , Danciu Paul , Lefter Andrei-Vlad , Afrăsânie Vlad-Adrian , Sur Daniel
Published: November 2023

Background: This study retrospective evaluates patients with stage IV melanoma treated with Nivolumab and Ipilimumab combination therapy from two regional oncology centers from Romania between the years of 2019 up to the end of 2022. Methods: The data were analyzed in SAS for Windows, V9.4. The survival curves were estimated using the Kaplan-Meier method, and survival distributions were compared with log-rank test. The effects of the main clinical and pathological variables on OS and PFS were investigated with Cox regression. Results: Kaplan-Meier curve of OS in all evaluable patients enrolled in the study resulted in a median OS of 346 days (95% CI: 150-NA) and a median PFS of 211 days (95% CI: 113-430). 45.3% of the patients experienced adverse events during the Nivolumab + Ipilimumab treatment with some of them having multiple organ systems involved. Discussion: The OS values were lower than that reported in approval clinical trials, but the results show a marked improvement when comparing to results obtained by chemotherapy regimens previously used in these scenarios. Conclusion: This study provides real-world insights into the survival data and safety profiles of combination therapy with anti-PD-1 antibodies and anti-CTLA-4 antibodies.
Enhancing Tablet Dissolution Insights: A Comparative Study of Predictive ANN, PLS, and SVM Model With NIR Spectra
Authors: Ringe Shruti , Kulkarni Shounak , Sutar Abhijeet , Kumar BV Suresh , Shenoy Anurag
Published: November 2023

The pharmaceutical industry is making significant strides in enhancing process comprehension through the development of concepts like Quality by Design (QbD) and Process Analytical Technology (PAT). This shift has moved from traditional offline testing methods to real-time estimation of product quality. The dissolution characteristics of pharmaceutical tablets play a crucial role in maximizing the release of medications and their bioavailability. One factor that can affect dissolution is the blending procedure. Inadequate mixing can lead to patches of concentrated active components or excipients within the tablet, resulting in inconsistent dissolution behavior. A study investigated the impact of blending time and speed on the dissolution behavior of Amlodipine tablets using near-infrared (NIR) spectroscopy and multivariate modeling. NIR spectra were collected for Amlodipine tablets produced under various blending conditions using a 2-level central composite design. Dissolving profiles were analyzed using a USP dissolution device. Multivariate analysis techniques, including principal component analysis (PCA), partial least squares (PLS), Support Vector Machine (SVM), and Artificial Neural Networks (ANN), were applied to the collected NIR spectra. The findings demonstrated that blending speed and time had a significant influence on the dissolving properties of Amlodipine tablets. Blending at faster speeds and for shorter durations resulted in excessive shear and insufficient mixing, ultimately reduced drug release. The multivariate models constructed using ANN outperformed SVM and PLS in predicting dissolution profiles based on NIR spectra. This research highlights the effectiveness of NIR spectroscopy and multivariate modeling in optimizing tablet dissolution. These advancements enable continuous manufacturing of high-quality pharmaceutical products.