bluuebunny/crossref_metadata_2025 huggingface dataset:
Apoptosis Induction Activity and Inhibition of MCF-7 Cell Proliferation in Active Isolate of Butterfly Pea Flower (Clitoria ternatea L.)
Authors: Rahayu Supiani , Muhtadi Muhtadi , Indrayudha Peni
Published: June 2023

Clitoria ternatea L. is one of the plants whose all parts have functional benefits for the human body. The flower petals are reported to be useful as anticancer. This study aims to determine the activity of inhibiting cell proliferation, and apoptotic induction activity and identify the chemical content of isolates from Clitoria ternatea L. Analysis of the results of the MTT assay test ethanol extract of butterfly pea flower has an IC50 value of 17.46 g/mL, CTEE has an IC50 value of 13, 19 g/mL, isolate 1 and isolate 2 of EAFCT had IC50 values of 6.79 and 7.12 g/mL. The results obtained were categorized as potent cytotoxic. Isolation of EAFCT compounds using radial system chromatography then analyzed GC-MS EAFCT isolates containing pyridine hydrochloride (51.42 %) and pentanal (2.79 %) and identified compounds using UV-Vis spectrophotometry and FTIR. The results of the cell proliferation inhibition test used a series of concentrations of IC50, ⅟2 IC50, ⅟4 IC50 and ⅟8 IC50, the CTEE obtained a doubling time of 178.47; 160.86; 151.18; 150.09, EAFCT is 188.53; 164.37; 156.82; 154.79, isolate 1 EAFCT is 212.96; 174.64; 148.53; 145.82 and isolates 2 EAFCT were 190.62; 168.23; 150.24; 148.94. Analysis of the apoptotic potential test results can be concluded from CTEE, EAFCT, isolates 1 and 2 EAFCT have apoptotic potential.
HIGHLIGHTS

The Clitoria ternatea 1 and 2 ethyl acetate fractions had a cytotoxic effect on MCF-7 cells with IC50 values of 6.79 and 7.12 μg/mL and inhibited the growth rate of MCF-7 cells with doubling times of 212.96 and 190.62 hours
Clitoria ternatea 1 and 2 isolates' ethyl acetate fraction induced apoptosis in MCF-7 cells, as indicated by the presence of orange fluorescent cells, indicating that the cells had died
The Ethyl acetate fraction of Clitoria ternatea isolate contains compounds with anticancer potential, including Pyridine hydrochloride and Pentanal

GRAPHICAL ABSTRACT
GC-MS Analysis, Antiglycation, Antioxidant and Anti-lipid Peroxidation Activities of Harungana madagascariensis Methanolic Stem Bark Extract
Authors: Adetayo Omotayo Mutiat , Modupe Akoro Seide , Sunday Adenekan , Cecilia Ogundare Oyinlade , Aminat Adesokan Ajoke , Bola Olorode Isiwat
Published: June 2023

Plants’ natural products make excellent lead for the development of new drugs used for prevention, management and treatment of communicable and non-communicable diseases. The specific aim of the study was to investigate the antioxidant and antiglycation activities of Harungana madagascariensis methanolic stem bark extract. The active compounds present in the plant were extracted using methanol by maceration and resulting extract was subjected to phytochemical screening, antioxidant and antiglycation analysis. The extract was fractioned on silica gel to isolate the antioxidant compounds domiciled in the extract and fractions were identified by bioautography. The H. madagascariensis methanolic stem bark extract showed the presence of tannins, alkaloids, saponins, steroids and flavonoids. From the antioxidant assays, the extract scavenged 2,2-diphenyl-1-picryhydrazyl (DPPH) and nitric oxide radicals, inhibited lipid peroxidation in a dose dependent manner showing IC50 higher than ascorbic acid while it inhibited albumin glycation with IC50 lower than ascorbic acid. From the 12 fractions obtained only 7 fractions showed antioxidant activity and quercetin, flavone, 6-hydroxyflavone, ferulic and o-coumaric acid were inferred. From the GC-MS analysis, fatty acids and their esters, terpenoids and steroids were identified such as Hexadecanoic acid ethyl ester (6.53 %), 9,12,15-Octadecatrienoic acid (5.92 %), 9,12,15-Octadecatrienoic acid methyl ester (0.95 %), vitamin E (1.22 %), phytol (3.87 %), squalene (1.66 %) and Pregn-5-en-3-ol, 21-bromo-20-methyl-(3.beta.)- (1.94 %). In conclusion, H. madagascariensis methanolic stem bark extract possessed antioxidant and antiglycation activities, thus, can be used for new drug development to reduce or combat oxidative stress related diseases in humans.
HIGHLIGHTS

The methanolic stem bark extract of Harungana madagascariensis exhibited strong antiglycation and antioxidant activities
Antioxidant compounds including flavonoids and phenolic acids (quercitin, flavone, 6-hydroxyflavone, ferulic and o-coumaric acid), terpenoids (vitamin E, phytol and squalene) fatty acids and their esters were found in the extract
The stem bark extract of Harungana madagascariensis could be used as a source of antiglycation and antioxidant activity for new drug development in preventing oxidative stress related diseases and diabetic complications

GRAPHICAL ABSTRACT
Ukrainian agricultural production profitability issues
Authors: Shahini Ermir , Korzhenivska Nataliia , Haibura Yuliia , Niskhodovska Olena , Balla Inna
Published: June 2023

The research relevance is predefined by the need to find ways to increase the profitability of agricultural production in the difficult economic conditions of Ukraine. The research aims to analyse the profitability of agricultural production, influencing factors and determination of directions for its improvement. The methodological approach is based on the analysis of statistical data on changes in production profitability; method of average values – to obtain the average value of indicators; comparison method – to compare data on profitability and productivity between types of products; graphic method – to display the results; method of generalization – for summarizing information about agricultural production. The main results that were obtained within the scope of this study should cover the analysis of the profitability of agricultural production by its types and crop yield and regions of the country in the conditions of the impact of negative factors on the agricultural sector during the period of martial law (in particular, the reduction of land suitable for agriculture, blocking many ways to sell products, complicating the supply of mineral fertilizers and other goods necessary for the functioning of the agrarian sector) and highlight directions for increasing profitability, namely increasing the yield of certain types of crops; reduction of feed costs for feeding animals by growing feed and electricity production efficiency through the use of renewable energy sources (sun, wind, biomass energy); development of pig meat production by increasing their population and quality of nutrition; creation of added value from products obtained by the producer on his own land, which will contribute to increased profitability and successful development of agriculture. Analysis of the supply and demand balance of grain and leguminous crops showed that their production exceeds the need for consumption of all types of grain. The results and conclusions have practical significance for agricultural producers in business management, as well as for the government in developing areas of support for the agricultural sector
Productivity of winter wheat depending on varietal characteristics and pre-sowing treatment of seeds with biological products
Authors: Korkhova Margaryta , Smirnova Iryna , Panfilova Antonina , Bilichenko Oleksandr
Published: June 2023

Winter wheat is the main food crop in the Steppe zone and the main agricultural crop in many countries of the world. The issues of intensifying grain production are inseparable from the production and use of new effective biological products for pre-sowing seed treatment, which positively affect the growth and development of winter wheat plants. The purpose of the study was to establish the effect of seed treatment before sowing with biological products on the productivity of winter wheat varieties. The study presents data on the results of an examination of 10 varieties of winter wheat for seed treatment with biological products in the conditions of the Educational and Scientific Practical Centre of the Mykolaiv National Agrarian University from 2020 to 2022. In the course of the study, generally accepted methods were used: system approach and system analysis, analysis and synthesis, field, and statistical. The influence of seed treatment with biological products and varietal characteristics of winter wheat on productivity was analysed. It was determined that the yield level depended and varied depending on the biological product used for pre-sowing seed treatment and the examined variety. Over the years of the study, biological products have affected the Winter wheat is the main food crop in the Steppe zone and the main agricultural crop in many countries of the world. The issues of intensifying grain production are inseparable from the production and use of new effective biological products for pre-sowing seed treatment, which positively affect the growth and development of winter wheat plants. The purpose of the study was to establish the effect of seed treatment before sowing with biological products on the productivity of winter wheat varieties. The study presents data on the results of an examination of 10 varieties of winter wheat for seed treatment with biological products in the conditions of the Educational and Scientific Practical Centre of the Mykolaiv National Agrarian University from 2020 to 2022. In the course of the study, generally accepted methods were used: system approach and system analysis, analysis and synthesis, field, and statistical. The influence of seed treatment with biological products and varietal characteristics of winter wheat on productivity was analysed. It was determined that the yield level depended and varied depending on the biological product used for pre-sowing seed treatment and the examined variety. Over the years of the study, biological products have affected the
Accurate Estimation without Calibration of the Complex Relative Permittivity of Multilayer Dielectric Material based on the Finite Integration Technique
Authors: Ho Manh-Cuong , Le Trong-Hieu
Published: June 2023

In this paper, a simple and effective solution is proposed to accurately estimate the complex relative permittivity of individual layers and multilayers of dielectric material samples from the S-parameters measured by two waveguide cells having equal or different lengths filled with the same vacuum/empty material without having to calibrate before performing experiments. The measurement system is set up by modeling using the Computer Simulation Technology (CST) software. In the modeling, a single layer/multilayer material sample is placed in the X-band rectangular waveguide and it has two ports used for the electromagnetic wave supply and measurement of S-parameters. From the S-parameters measured, the complex relative permittivity of individual layers and the multilayers of the material samples are estimated by the proposed method. The known single-layer and multilayer materials such as Garlock, Bakelite, and Teflon have different dielectric constants and thicknesses. The results show that the complex relative permittivity of the samples matches the measured and calculated values of S-parameters in the frequency range of 8.2GHz to 12.4GHz.
Evaluation of HMA Modified with Titan Polymer
Authors: Alnaqib Hassan M. , Bazuhair Rabeea W.
Published: June 2023

Improving the quality of the road pavement and ensuring the safety of the drivers on the road are issues of paramount importance. Cracking and rutting are two of the most common damages that occur to asphalt pavement due to environmental effects and traffic. Utilizing a modified binder is a solution for improving the pavement's resistance to these damages and enhancing pavement durability. This study investigates the performance of Hot Mix Asphalt (HMA) modified with Titan7205 polymers and then compares it with that of a control mix of modified HMA with Styrene-Butadiene-Styrene (SBS) or crumb rubber (CR). Two percentages of Titan7205 were utilized to find out which dose provided better performance. HMA was prepared by adding polymers with different percentages (3% and 5% Titan7205, 4% SBS, and 8% CR). After preparing the samples, they were tested (unconditioned and AASHTO R30) for Dynamic Shear Rheometer (DSR) testing, Cantabro Mass Loss (CML), Tensile Strength Ratio (TSR), and Indirect Tensile Tension (IDT). The results showed that the mix with 3% of Titan7205 has a similar or better performance than the mixes with the other polymer additives utilized in this study.
Analysis of Ionospheric Scintillations using GPS and NavIC Combined Constellation
Authors: Nimmakayala Shiva Kumar , Vemuri Bala Sai Srilatha Indira Dutt
Published: June 2023

The disturbances and irregularities in the ionosphere are the primarily recognized ramifications of space weather called scintillations. Irregularities in the electron densities are the source of the ionospheric scintillations. This article investigates the ionospheric scintillations, which are predominant in the trans-equatorial and equatorial regions. Based on the data from a multi-constellation Global Navigation Satellite Systems (GNSS) receiver at the Chaitanya Bharathi Institute of Technology Hyderabad, the relationship between the amplitude scintillation index S4 and the rate of change of total electron content (ROTI) is examined. The correlation coefficient between S4 and ROTI is demonstrated in this article. The outcome validates the usefulness of the ROTI in identifying the scintillations.
A Non-destructive Radar Device for Detecting Additive Materials in Concrete
Authors: Quy Vu Ngoc , Dao Toan Thanh , Trung Ho Thanh
Published: June 2023

The use of electronic devices based on electromagnetic waves is promising for inspecting additives in structural concrete. However, the existing commercial devices are high-cost and do not publicly provide circuit design information. To overcome this issue, this study designed a low-cost nondestructive testing device with a radar sensor, using an HB-100 radar sensor module to generate and receive the radar wave. A suitable bandpass filter was used to suppress electrical noise in the received signal, an Arduino board was used for signal processing, and the measured data were displayed on a computer. The output at the IF pin of the sensor module presents the Doppler frequency and absorbance of the target materials. The device was tested to detect additives inside the concrete. An additive material can be recognized by the fact that the obtained signal magnitudes are different with different additive materials. The findings in this study can contribute to making a low-cost nondestructive testing device based on radar technology for structural concrete inspection.
The Use of Recurrent Nets for the Prediction of e-Commerce Sales
Authors: Aldhahri Eman
Published: June 2023

The increase in e-commerce sales and profits has been a source of much anxiety over the years. Due to the advances in Internet technology, more and more people choose to shop online. Online retailers can improve customer satisfaction using sentiment analysis in comments and reviews to gain higher profits. This study used Recurrent Neural Networks (RNNs) to predict future sales from previous using the Kaggle dataset. A Bidirectional Long Short Term Memory (BLTSM) RNN was employed by tuning various hyperparameters to improve accuracy. The results showed that this BLTSM model of the RNN was quite accurate at predicting future sales performance.
Predictive value of imaging manifestations of supratentorial hemorrhage in hematoma enlargement and clinical prognosis
Authors: Bai Qingke , Wang Feng , Zhao Zhenguo , Zheng Ping
Published: June 2023

Introduction

Intracerebral hemorrhage (ICH) is an important cause of death and disability. This study aimed to explore the imaging indicators identifying hematoma expansion in primary ICH and to provide a basis for its clinical treatment.

Material and methods

Hematoma expansion was evaluated by plain computed tomography (CT) scan and multi-detector-row CT angiography (MDCTA).

Results

This study included a total of 203 patients with intracerebral hemorrhage. The size of the hematoma at the time of admission was 32.5–92.3 mL (average, 45.5 mL). Original or reconstructed MDCTA images with contrast extravasation were available in 35 cases (17.2%). Patients were divided into two groups based on whether or not hematoma expansion had occurred: hematoma expansion group (n = 87) and no hematoma expansion group (n = 116). Patients with spot signs in the two groups were 37.93% and 3.45%, respectively, and those with spot sign ± blend sign ± black hole sign ± island sign (%) were 48.30% and 1.72%, respectively, with significant statistical differences. The sensitivity, specificity, and positive and negative predictive values of hematoma enlargement were 37.93%, 98.27%, and 94.29% and 67.86%, respectively. The sensitivity, specificity, and positive and negative predictive values of blend density sign ± irregular sign in predicting hematoma enlargement in ICH patients were 97.7%, 76.7%, and 75.9% and 97.8%, respectively.

Conclusions

Blend density sign ± irregular sign can be used as substitute signs. The more irregular and uneven density the hematoma, the more likely it is that the hematoma will be enlarged.
Determining the clarithromycin-resistance of helicobacter pylori in first-line therapy with melting curve analysis
Authors: Yılmaz Kemalettin , Uygun Ahmet , Kubar Ayhan
Published: June 2023

Aims: We aimed to determine the usefulness of melting curve analysis with the PCR technique in predicting the primary
clarithromycin resistance of H. pylori before antibiotic use.
Methods: 46 H. pylori positive clarithromycin based therapy naïve patients were included in the study. After proving H. pylori positivity with a real-time test, histopathological examination and rapid urease test, patients were treated with clarithromycinbased triple therapy for 14 days. Then patients were underwent a control endoscopy and tissue samples were taken 8 weeks after the initial endoscopy. The presence of H. pylori was investigated by using TaqMan-based real-time PCR and clarithromycin resistance was determined using two different molecular methods:melting curve analysis and DNA sequencing.
Results: In total 18 patients (39.1%) were diagnosed as H. pylori positive on histopathological examination and 26 (56.5%) were diagnosed as H. pylori positive with TaqMan-based PCR, after triple therapy. According to results of melting curve analysis, primary resistance was found in 4 samples before treatment and secondary resistance was found in a different 4 samples after treatment. The DNA analysis showed that 9 patients had primary mutations in the pre-treatment group:4 patients had A2142CA2143G(T), 3 patients had T2182C, and 2 patients had both mutations, and also showed that 6 patients had mutations in the post-treatment group:4 patients had A2142C-A2143G, 2 patients had T2182C mutations.
Conclusion: PCR based melting curve analysis may fail in determining clarithromycin resistance before eradication therapy.
Hence, this method may also be used in combination with another molecular method such as DNA sequence analysis for
improved detection of clarithromycin resistance.
Donor cell leukemia after allogeneic hematopoietic stem cell transplantation: a case report
Authors: Abedi Amir Hossein , Çelik Serhat , Özçelik Yılmaz Zeynep Dilan , Güven Zeynep Tuğba , Akalın Hilal , Kaynar Leylagül
Published: June 2023

A 48-year-old man was diagnosed Acute myeloid leukemia with FLT3 ITD positive and PML/RAR?- negative. Remission was
achieved after induction and consolidation chemotherapy. Allogeneic hematopoietic stem cell transplantation was performed
from his full matched sibling donor. He relapsed after 5 years and his bone marrow examination revealed PML/RAR?-
positive Acute promyelocytic leukemia. t(15:17) was positive and FLT-3 ITD was negative. Cytogenetic and molecular analysis
confirmed donor cell origin. Donor didn’t develop Acute promyelocytic leukemia.
Current diagnosis and treatment in central serous chorioretinopathy
Authors: Horozoğlu Ceran Tuğce , Çıtırık Mehmet
Published: June 2023

Central serous chorioretinopathy (CSCR) diagnosis and follow-up are performed with multimodal imaging methods. Fundus fluorescein angiography, optical coherence tomography (OCT), fundus autofluorescence, and indocyanine green angiography can be used in the diagnosis of patients with CSCR. OCT stands out as the gold standard for imaging, diagnosis, and follow-up. Although there is no gold standard method in treatment.
The evaluation of asthma by gender and age groups in Turkey, in 1990-2019: incidence, prevalence, mortality, and disability-adjusted life years
Authors: Dinçer Metin , Kocakaya Mustafa , AKYOL Mesut
Published: June 2023

Aims: The aim of this study was to evaluate the incidence and prevalence of asthma, asthma-related DALYs and deaths, and
risk factors for asthma by genders and age groups during the study years in Turkey.
Methods: The data used in the study were obtained from the estimation data prepared by the Institute for Health Metrics and Evaluation on asthma for Turkey by the global burden of disease study covering the years 1990-2019. During the study years period, death from asthma and Disability-Adjusted Life Years (DALYs) were used as dependent variables. In addition, the effects of Occupational Asthmagens (OA), Smoking (SM), and High Body Mass Index (HBMI), which are known as risk factors for asthma-related deaths and DALYs, were investigated. Comparisons of the variables according to gender and age groups were made with the Mann-Whitney test. The relationships between the variables were examined with the Spearman rank correlation coefficient (Rho).
Results: A statistically significant difference was found between the mean rank of total prevalence number, total incidence
number, total number of deaths and DALYs scores by gender. Asthma-related deaths due to risk factors (OA, HBMI, SM)
were found to be correlated with DALYs and the total number of asthma deaths. Total asthma deaths, and asthma-related
deaths because of HBMI and DALYs because of HBMI-induced asthma in women; deaths from asthma because of OA, SM, and DALYs from asthma because of OA and SM were found to be higher in males.
Conclusion: HBMI in women and SM and OA in men stand out as risk factors. Therefore, as a result of a detailed investigation of the risk factors leading to the development of asthma, policies should be developed for gender and age groups, and necessary precautions should be taken.
Strengthening Students' Religious Character through Extracurricular Activities at Muhammadiyah Elementary School
Authors: Kartikasari Renata , Amrullah Muhlasin , Hikmah Khizanatul
Published: June 2023

This research aims to determine the implementation, supporting factors, and inhibiting factors of strengthening religious character in the extracurricular activities of Da'i Cilik and BTQ. The research conducted is qualitative research with a phenomenological approach. The subjects of this research are the school principal and extracurricular coaches. The data collection techniques used include interviews, observation, and documentation. The researcher serves as the instrument in this research. The data analysis techniques used include data reduction, data presentation, and conclusion drawing. The data validity is tested through triangulation of sources and techniques. The results of this research show the implementation of strengthening religious character education through the extracurricular activities of Da'i Cilik and BTQ. This includes strengthening religious character through exemplary activities such as habituation, preaching material, praise and advice, and assessment. The supporting factors for strengthening religious character include the availability of facilities and infrastructure, student attendance and seriousness, and parental support. The inhibiting factors include students' lack of self-confidence and the absence of props. The impact of strengthening religious character on students is evident in increased awareness and obligations as Muslims, increased diligence in performing prayer and reading the Qur'an, improved polite and respectful attitudes among students, enhanced self-confidence, independence, and discipline in daily activities in accordance with Islamic teachings.
Comparing morphologic features and complications of main clear corneal incision between junior and senior residents observed using anterior segment optical coherence tomography
Authors: Gharaee Hamid , Sedaghat Mohammad-Reza , Sadeghi Javad , Tabesh Hamed , Gharouni Ahmad , Ghasemi Moghadam Somayeh , Nozari Vahide , Beigi Samira
Published: June 2023

Background: Wound construction is a critical step in phacoemulsification. Using anterior segment optical coherence tomography (AS-OCT), we compared the morphological features and complications of main incisions made by junior or senior residents during phacoemulsification.

Methods: This cross-sectional comparative study included eyes with senile cataracts that underwent uneventful phacoemulsification with a clear corneal incision made by seven senior and eight junior ophthalmology residents. All eyes underwent postoperative image acquisition using AS-OCT on day one and at three months, examining for morphological features and potential complications of the main incision.

Results: We included 50 eyes of 50 patients with a male-to-female ratio of 22 (44%) to 28 (56%); 26 (52%) were operated on by junior residents and 24 (48%) by seniors. The mean geometric features of the main incisions and the frequency of early and late wound complications were comparable between the two groups (all P > 0.05). A significant correlation was found between the incision length and angle with the superior (r = + 0.80; P < 0.001 and r = - 0.63; P < 0.001, respectively) and inferior (r = + 0.84; P < 0.001 and r = - 0.68; P < 0.001, respectively) areas of the incision, as well as between the length and angle of incision (r = - 0.74; P < 0.001). The number of planes in the wound architecture was not significantly different according to senior or junior resident status (P > 0.05). Although the number of eyes with stromal hydration was significantly greater for junior residents than for seniors (P < 0.001), the corneal thickness at the entrance to the cornea or the anterior chamber, presence of endothelial wound gaping, and Descemet’s membrane detachment were comparable between eyes with and without stromal hydration (all P > 0.05). At three months, 29 (58%) patients returned for examination, in whom seven (24%) had late wound complications.

Conclusions: This study found no significant differences in the performances of junior and senior residents in terms of wound construction or its associated complications. However, considering the overall rate of some observed wound-related complications, we recommended revision of the resident educational curriculum concerning the structure and complications of the main incision.
Outcomes after bilateral implantation of AcrySof IQ PanOptix trifocal intraocular lens: a prospective interventional study
Authors: Sahin Vedat , Unal Mustafa , Ayaz Yusuf
Published: June 2023

Background: Implantation of multifocal intraocular lenses (IOLs) is becoming increasingly popular for the treatment of visual demands at various distances in patients undergoing phacoemulsification cataract surgery. We aimed to assess the visual performance and rates of photic phenomena, posterior capsule opacification (PCO), and spectacle independence in patients with bilateral implantation of the AcrySof® IQ PanOptix® multifocal IOL model TFNT00 at one and six months postoperatively.

Methods: This prospective interventional cohort study included adult patients who underwent uneventful phacoemulsification cataract surgery with bilateral implantation of AcrySof® IQ PanOptix® IOL. Uncorrected and corrected visual acuities at far, intermediate, and near distances were measured preoperatively and at the one- and six-month postoperative follow-up examinations. The rates of photic phenomena, postoperative need for near and distance spectacles, and PCO were also recorded.

Results: We included 164 eyes of 82 patients with a male-to-female ratio of 38 (46.3%) to 44 (53.7%) and a mean (standard deviation [SD]) age of 52.37 (7.62) years. There were statistically significant improvements in the visual acuities of both eyes across all distances at the one- and six-month follow-up examinations compared to the preoperative values (all P < 0.001), except for corrected near visual acuity in the right eye (P > 0.05) at six-month. We also detected significant postoperative improvements in visual acuities of both eyes across all distances at the six-month follow-up compared to values at the one-month follow-up (all P < 0.05), except for corrected near visual acuity in the right eye (P > 0.05). The photic phenomenon was reported by 12 (14.6%) of the 82 patients at the six-month postoperative follow-up. Five (6.1%) and eight (9.8%) of the 82 patients reported using spectacles for distance and near, respectively. Additionally, PCO developed in 19 (11.6%) of the 164 included eyes, although it was not clinically significant at six months.

Conclusions: The AcrySof® IQ PanOptix® IOL model TFNT00 is recommended for use, given its excellent performance in all ranges of vision, a high rate of spectacle independence, and a good safety profile. Future comparative studies with longer follow-up periods are warranted to verify superiority of its performance over that of other available multifocal IOLs.
What is the Proper Peasant to Do? Changes in Perspective on Cultivating Land in Czech Ruralism
Authors: Derkova Vladimira
Published: June 2023

The paper focuses on cultural changes that the depiction of land cultivation in Czech ruralism literature (authors like Josef Knap, František Křelina, Václav Prokůpek, etc.) goes through in Modernism. It refers to the impact of political discourse and the influence of media – especially newspapers – at the time. The analysis points to the relevance of how traditionalist literature discourse incorporates modern approaches to agriculture and new modes of representation of the countryside.
The Socialist Realist Structure of Marin Predaʼs Moromeții
Authors: Rogozanu Costi
Published: June 2023

Taking into account the two Romanian modernities that alternated, and clashed throughout the twentieth century – the capitalist, and the communist, respectively –, with their different public assessment, the paper analyzes realist patterns emerging in the post-1945 Romanian narrative. These patterns did not only concern new characters and topics, but also the shaping of a new, mass-scale, intensively cultured reader. To the same extent, the respective age saw the replacement of traditional bourgeois narrative voices with rural and proletarian viewpoints (in a marked shift from the simply rural or proletarian characters). I will explore this new ideology of the narrative voice, and its indebtment to the socialist realist paradigm, in Marin Predaʼs landmark novel Moromeții. The case analyzed proves how Romanian postwar fiction helped naturalize socialism, and how this very ideological backbone might strengthen the value of the novel in the long run.
VẬN DỤNG MÔ HÌNH DẠY HỌC KẾT HỢP TẠI KHOA KỸ THUẬT CÔNG NGHỆ - TRƯỜNG ĐẠI HỌC HÙNG VƯƠNG TRONG BỐI CẢNH CHUYỂN ĐỔI SỐ HIỆN NAY
Authors: Nguyễn Hương , Nguyễn Lợi , Nguyễn Huyền
Published: June 2023

Bài viết đề cập đến việc áp dụng mô hình dạy học kết hợp trong bối cảnh chuyển đổi số hiện nay tại khoa Kỹ thuật công nghệ - Trường Đại học Hùng Vương. Trong đó trình bày về cách thức vận dụng phù hợp với điều kiện của khoa - trường, phân tích đánh giá thực trạng để thấy được hiệu quả, lợi ích, tồn tại, khó khăn, làm cơ sở để các nhà giáo dục tìm ra các phương án cải tiến, điều chỉnh sao cho mang lại hiệu quả thiết thực trong đào tạo.
PHÁT TRIỂN ỨNG DỤNG MẠNG XÃ HỘI DỰA TRÊN CÁC KỸ THUẬT FIREBASE VÀ REACT NATIVE
Authors: Bùi Phong , Trần Long , Nguyễn Ngọc
Published: June 2023

Cùng với sự phát triển nhanh chóng của công nghệ thông tin và truyền thông, mạng, các trang mạng xã hội được đánh giá là có tiềm năng tiếp cận tin tức và thông tin, kết nối các mọi người trên internet với nhiều mục đích khác nhau không phân biệt không gian và thời gian. Mạng xã hội là công cụ tạo ra một “thế hệ thông tin toàn cầu” có khả năng chưa từng có để tạo lập, sản xuất, chia sẻ và tham gia vào những gì đang diễn ra của cuộc sống. Mạng lưới toàn cầu cho phép con người đưa tin tức, suy nghĩ, ý tưởng và hình ảnh đi bất cứ đâu, vào bất kỳ thời điểm nào. React Native là một framework đang dần trở nên phổ biến. Hàng nghìn ứng dụng được tạo ra có dính dáng đến React native. Những cái tên lớn như Facebook, AirBnB, Uber và nhiều công ty khác cũng đã chọn React native để xây dựng ứng dụng của họ. Firebase là một nền tảng sở hữu bởi Google để phát triển ứng dụng di động và trang web, bao gồm các API đơn giản và mạng mẽ và không cần backend hay server. Firebase còn giúp các lập trình viên rút ngắn thời gian triển khai và mở rộng quy mô của ứng dụng mà họ đang phát triển. Bài báo này trình bày ứng dụng công nghệ React Native và Firebase để phát triển ứng dụng chia sẻ thông tin cho người dùng (hướng tới người dùng là sinh viên các trường đại học) ứng dụng mạng xã hội chạy trên nền tảng thiết bị di động một cách hiệu quả.
ẢNH HƯỞNG CỦA RỦI RO CẢM NHẬN ĐẾN Ý ĐỊNH SỬ DỤNG MOBILE BANKING TRÊN ĐỊA BÀN THÀNH PHỐ HÀ NỘI
Authors: Nguyễn Yến , Nguyễn Hạnh , Lê An , Vũ Diệu
Published: June 2023

Khi dịch vụ ngân hàng ngày càng phát triển, khách hàng bắt đầu đòi hỏi một hình thức trải nghiệm mới thuận tiện, đáp ứng được nhu cầu thanh toán bất cứ lúc nào mà không cần sử dụng tiền mặt. Với sự tiến bộ của công nghệ - viễn thông, các ngân hàng thương mại liên tục phát triển Mobile Banking (dịch vụ ngân hàng di động) để đáp ứng nhu cầu của thị trường. Tuy nhiên trong quá trình sử dụng Mobile Banking, khách hàng còn gặp phải các vấn đề về công nghệ và phi công nghệ. Trước sự gia tăng các loại tội phạm trên môi trường mạng, người dùng lại càng thận trọng và chưa hoàn toàn tin tưởng loại hình dịch vụ này. Chính vì những lý do trên, nghiên cứu tập trung phân tích các yếu tố ảnh hưởng đến ý định sử dụng Mobile Banking dựa trên lý thuyết mô hình chấp nhận công nghệ và thuyết về rủi ro cảm nhận. Dữ liệu hợp lệ được tập hợp từ 512 người dân trên địa bàn thành phố Hà Nội nhằm kiểm định mô hình đề xuất. Nghiên cứu sử dụng phương pháp mô hình cấu trúc tuyến tính để nhận diện sự ảnh hưởng của các yếu tố thuộc nhóm rủi ro cảm nhận (gồm: rủi ro riêng tư, rủi ro tài chính, rủi ro tâm lý, rủi ro thời gian, rủi ro hoạt động) đến cảm nhận tính hữu ích và ý định sử dụng Mobile Banking, đồng thời nghiên cứu ảnh hưởng cảm nhận tính hữu ích đến ý định sử dụng Mobile Banking. Dựa trên kết quả nghiên cứu, một số bình luận và kiến nghị được đưa ra nhằm thúc đẩy sự phát triển của Mobile Banking.
Pelanggaran Privasi Dalam Program Realita Investigasi Polisi di Indonesia: Ancaman, Kebijakan, Dan Kebutuhan Pembaruan
Authors: Ditia Saputra Dandi , Ayu Pramesty Ligar , Farah Munifah Nabila
Published: June 2023

The high popularity of police investigation reality programs in content broadcast on television and online media (YouTube) increases the possibility of doxing. Several laws, especially Law no. 19 of 2016, have provisions regarding the protection of personal life. However, until now, there has been no regulation that clearly regulates the authority for the participation of television stations in the process of finding investigative facts. This paper aims to find a legal basis for privacy violations against police investigation reality program coverage and to formulate a more comprehensive privacy protection instrument. This research is a normative research with a statutory approach. The research shows that there is a debate between public interest and privacy protection in the coverage of police investigative reality programs, as well as violations of laws and ethical codes committed by the Republic of Indonesia police and private television stations. The presence of the concept of protecting privacy for the public, especially suspects, is expected to be the main value base considered in every coverage of the police investigative reality program.

Tingginya popularitas program realita investigasi polisi dalam konten penayangan di media penyiaran televisi dan media online (YouTube) meningkatkan kemungkinan doxing. Beberapa Undang-Undang terutama Undang-Undang No. 19 Tahun 2016 memiliki ketentuan mengenai perlindungan kehidupan pribadi, walaupun demikian sampai saat ini belum ada regulasi yang dengan jelas mengatur mengenai otoritas keikutsertaan stasiun televisi dalam proses pencarian fakta investigasi. Tulisan ini bertujuan mencari dasar hukum pelanggaran privasi terhadap peliputan program realita investigasi polisi dan merumuskan instrumen perlindungan privasi yang lebih komperhensif. Penelitian ini merupakan penelitian normatif dengan pendekatan perundang-undangan. Penelitian menunjukkan adanya perdebatan antara kepentingan publik dan perlindungan privasi dalam peliputan program realita investigasi polisi serta adanya pelanggaran hukum serta kode etik yang dilakukan oleh kepolisian Republik Indonesia dan stasiun televisi swasta. Hadirnya konsep perlindungan privasi bagi masyarakat khusunya tersangka diharapkan menjadi basis nilai utama yang diperhatikan dalam setiap peliputan program realita investigasi kepolisian.
Examination of Digital Competences of Teachers According To Different Variables
Authors: GÜMÜŞ Muhammed Murat , KUKUL Volkan
Published: June 2023

This study examines the digital competence of teachers according to different variables. In this direction, 695 teachers working in primary, secondary, and high schools participated in the study. The Teacher Digital Competence Scale (2022), developed by Gümüş and Kukul, was used in the study analyzed using the scanning model. In line with the results obtained in the study, while digital competencies differ according to gender, and age range, no difference was observed according to school type, and foreign language levels. On the general evaluation of the analyses, it is thought that although the teachers have medium-level digital competences, considering the difficulties experienced during the pandemic period, the digital competences of the teachers observed at the medium level are eventually insufficient and the teachers should develop themselves in this regard.
High School Students' Evaluations on the Reflections of Geographical Information on Daily Life
Authors: SÖZCÜ Ufuk , TÜRKER Abdullah , DÜNDAR Erkan
Published: June 2023

Geography is a critical tool for understanding the physical, social, economic, and political characteristics of places around the world and is important for grasping the various factors that shape people's lives and decisions. Knowledge of geography directly or indirectly affects people's daily lives by determining the characteristics of settlements, natural resources, climatic conditions, economic activities, natural disasters, or cultures and societies around the world. This research was carried out with 10th grade students who tried to gain geographical knowledge systematically through a geography course. The aim of the research is to reveal how the students' geography knowledge is reflected in their daily lives. A semi-structured interview form created by the researchers was used to collect data in the study that employed phenomenology design, one of the qualitative research methods. The obtained data were analyzed using the descriptive analysis approach, and results were gathered with regard to the students' level of interest in the geography course, the factors affecting this level of interest, the definition of geography knowledge and the future contribution of geographic knowledge, and the use of this knowledge in daily life. The main conclusion of the study is that one-third of students don’t use geography in their daily lives. In light of this circumstance, it could be advised to design geography topics based on activities, using real-world examples in a practical way.
Zooming in the Timeline: Investigation of the Case of Pseudo-Archimedes by Preservice Teachers
Authors: KOŞTUR Hakkı İlker
Published: June 2023

The study proposed an inquiry-based activity for an undergraduate History of Science (HOS) course. The activity aimed to promote collaboration, engagement, and motivation among students from various disciplines. The participants in this activity were 40 undergraduate students enrolled in different teaching programs at a private university. The course followed a timeline approach to teaching HOS, supplemented by weekly research questions and short activities. The specific focus of this activity was to investigate whether Archimedes designed a water clock. Students worked in groups to conduct research on the question and develop a group claim based on the evidence they collected. The course discussions resulting from this activity yielded comprehensive outcomes that contributed to the course's timeline, covering the transition from antiquity to the Middle Ages. These discussions touched upon various historical events, including the closing of the Platonic Academy, the birth of the House of Wisdom, cultural and geographical factors in the translation movement, and the concept of pseudepigrapha. Importantly, the study noted that many of these events between antiquity and the Middle Ages were not commonly mentioned in traditional HOS course books. By engaging in this activity, participants were able to zoom into the timeline and uncover fascinating historical events. The research, collaboration, and discussions brought about a sense of excitement among the students. This activity demonstrated that incorporating such an approach can enhance the narrative nature of HOS courses. The success of the activity depends on the time allocated and the content of the course, suggesting that it could be tailored to different contexts and course objectives.
The Role of Structural Characteristics of Soft Sediment on Absorption of Total Hydrocarbon Content (THC) and Physicochemistry Due to Human Induced Pollution in The Lower Bonny Estuary, Rivers State, Nigeria
Authors: K.J Alagoa , S.T. Iderima
Published: June 2023

The role of structural characteristics of soft sediment on absorption of total hydrocarbon content (THC) and physicochemistry due to human induced pollution in the lower bonny estuary were studied in a bid to measure the danger of human actions along the catchments on the estuary. Samples were collected and analyzed from five sampling stations representing fuel depot site, garbage dump, fishing spots, living quarters and an upstream station far removed from direct human impacts (control). Sediment samples were collected for six months representing wet and dry seasons. Samples were analyzed for THC, Organic Carbon, phosphate (PO4), Electrical conductivity (EC), and pH. Sediment particle was also determined by the hydrometer method. Result from the investigation reveal that there were significant seasonal differences in measured parameters (p<0.05). pH and THC and EC in wet season>dry season. While Organic Carbon and PO4 in wet season < dry season. Sample stations did not show any significant difference (p>0.05). Soil sediment analyses reveal that percentage of sand in sediment was uniform throughout the wet and dry season and all sample stations. Clay content was constant in all stations in dry season but fluctuated in the wet season between stations. Silt content in sediment fluctuated between stations in both wet and dry seasons. THC and physico-chemical parameters did not have any direct correlation with sediment characteristics.Station 5 (control) revealed lower values in almost all measured. parameters compared to other stations, implying greater ecological stability in the control station. The findings of this work is suggestive of the fact that Bonny estuary is under a subtle threat from land-based activities.
STUDY THE FREQUENCY OF NON DIABETIC AND NORMOTENSIVE STUDENTS OF UOG VISITING THE NSMC HEALTH CARE CENTRE GUJRAT, PAKISTAN
Authors: NASIR ALI  , AWAIS ASIF  , ZIA GHAFFAR  , ASMA TARIQ  , ROBINA RASHID  , MOHSIN IKRAM
Published: June 2023

The presenting complaints made by patients were recorded. Total 303 (males, 99; females, 204) patients were included in the study. RBG were measured with glucometer, BP with sphygmomanometer and BMI was recorded, to study the distribution of patients according to their living(residence), obesity, different dietary habits, blood glucose level and blood pressure was measured. Frequency distribution characteristics of patients lodging, presenting complaints in Health Care Centre, with the assistance of Biochemistry department of NSMC, UOG. The nature and outcome of patients were assessed and tabulated accordingly. From a total of 303 patients presented to health care center during the study period having 99 males & 204 females with ratio of hostelite males 30, hostelite females 36, days scholar male 69 and days scholar female 168 (Table No.1). It has been observed that different individuals came with different dietary habits, but mixed food habit was observed in 214 individuals Table No.4). There are number of individuals who were suffered from variety of complaints like (Allergy, n=14; Gastritis/Food Poisoning, n=87; UTRI/Sore throat, n=169; Flu/Body ache/Fever, n=30; Muscular Pain, n=02 and Toothache ē Headache, n=01). Eight patients were obese and eight patients were under weight (Table No.2). Three patients were presented with high blood pressure and no patient has high blood glucose level (Table No. 3).
ROLE OF ERYTHROMYCIN IN THE MANAGEMENT OF GASTRO ESOPHAGEAL REFLUX IN INFANTS
Authors: MARYAM WAHEED  , SADIA CHIRAGH
Published: June 2023

Regurgitation and vomiting of milk due to GER is a common problem in infants especially under 6 months of age. It is a self limiting condition and improves as the infant becomes older & starts sitting, but in some cases pharmacological treatment may be required.

Objective: This study aims to evaluate the effectiveness of erythromycin as a prokinetic agent in otherwise healthy infants with gastro esophageal reflux.

Design: Interventional study

Place & Duration of Study: Outpatient Pediatric Clinic of Govt. Kot Khawaja Saeed Teaching Hospital (KEMU) Lahore. From 1st May 2014 till 31st October 2014.

Patients & Methods: Infants (15 days to 1 year) attending Pediatric Outpatient Clinic who were otherwise healthy except for history of regurgitation and vomiting after feed were included in the study. Erythromycin drops were started in a dose 10-15 mg/kg/day for a period of 2 weeks.

Results: A total of 30 infants, 15 days to 10 months age were included in the study. Male to female ratio was 1.1:1. Twelve infants presented with history of regurgitation, twelve with history of vomiting and six with regurgitation and vomiting both. Twenty infants showed improvement within a week. Four infants showed partial improvement and four did not respond at all, while two infants were lost to follow up.

Conclusion: Erythromycin has been found a helpful drug for the management of regurgitation and vomiting in infants.