bluuebunny/crossref_metadata_2025 huggingface dataset:
THE PROBLEM OF CRACK OPENING IN REINFORCED CONCRETE
Authors:   Moscow State University of Civil Engineering, KOLCHUNOV VL.I. ,   Research Institute of Construction Physics of the Russian Academy of Architecture and Construction Sciences
Published: March 2024

The article discusses various aspects of the problem of assessing crack opening in reinforced concrete based on experimental data obtained in recent studies. The author proposed a classification of crack types, introduced a number of new hypotheses, established experimentally the effects of deformation of reinforced concrete in the crack zone. The principles formulated on their basis include schemes for the distribution of force flows between cracks, the concept of progressing main cracks and the deformation effect in reinforced concrete - a special two-console element in the local region near the crack banks, new generalized hypotheses, theorems and functionals about linear and angular deformations of the compressed and tensile zones of reinforced concrete element sections at all levels of elastic-plastic deformation. The proposed model of composite rods in the form of single strips for determining the stiffness of a section of reinforced concrete with intersecting cracks has made it possible to reduce the differential equations of the theory of composite rods by an order of magnitude when solving such problems. The connection is established and analytical dependences for displacements in the crack with opening and shear of the crack banks are given. The main vector of displacements and the angle of equidirectional forces in the reinforcement crossing the crack are determined. Calculated dependences for determining the level distances between cracks and crack opening widths are constructed. Within the framework of the general methodology of the considered problem of crack opening in reinforced concrete, using the formulated principles, a general combined numerical-analytical model of the structural mechanics of reinforced concrete is constructed, which takes into account the deformation effect in the crack modeled by a double cantilever element, the types of cracks, the spatial surface of strain distribution in the cross section with the crack and other experimentally determined features of the mechanics of reinforced concrete, cracks types, spatial surface of strain distribution in the cross-section with a crack and other experimentally determined features of reinforced concrete mechanics.
THE USE OF SHOTCRETE TO STRENGTHEN MASONRY
Authors:   National Research Moscow State University of Civil Engineering, SIMAKOV OL.A.
Published: March 2024

The technology of reinforcing structures by the shotcrete method has been known for more than a hundred years. The first experiments using this method refer to approximately 1910-1912. At the same time, at this moment there are questions both with the calculation methodology of reinforced structures, and taking into account the new properties of shotcrete, which appear in this material as a result of improving equipment and material for shotcrete directly. This article examines the experience of calculating, projecting and applying shotcrete to strengthen load-bearing masonry structures accumulated over the past two years. The current methods of work are presented, as well as the corresponding methods of calculation justification (taking into account the stage of work on strengthening structures) for objects that are difficult from an engineering point of view: arches, brick walls with a large percentage of damage, including as a result of mine-explosive impacts. The results of the implementation of reinforcement of stone masonry by the method of one-sided applications of shotcrete are shown.
Overcoming Breast Cancer Drug Resistance: A Novel Approach Using siRNA-Mediated P-glycoprotein Downregulation to Enhance Vinorelbine Efficacy
Authors: Abbasfard Zahra , Behzad-Behbahani Abbas , Rastegari Banafshe , Naeimi Sirous , Moghanibashi Mehdi , Safari Fatemeh
Published: March 2024

Purpose: Cancer, the second leading cause of mortality worldwide, represents a global health challenge, primarily due to drug resistance. Vinorelbine is a chemotherapeutic agent that disrupts cancer cell growth by targeting microtubules and inducing apoptosis. However, drug resistance remains a formidable obstacle. This resistance is caused by various factors including genetic mutations, drug efflux mechanisms, and DNA repair systems. Resolution of this challenge requires an innovative approach. This study investigated the potential of small interfering RNA (siRNA) to target and downregulate a vinorelbine-resistant MCF-7/ADR breast cancer cell line. Methods: Cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM) 10% fetal bovine serum/penicillin/streptomycin. An siRNA targeting ABCB1 was designed and synthesized, and the cells were transfected with siRNA at final concentrations of 10, 20, and 30 nM. The3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to assess cell viability. ABCB1 mRNA expression levels were determined by real-time polymerase chain reaction (PCR). Results: MCF-7 cells exhibited a higher sensitivity to vinorelbine than MCF-7/ADR cells. MCF-7/ADR cells exhibited resistance to vinorelbine at concentrations, 12.50 and 25.00 μM. Treatment with siRNA significantly reduced ABCB1 expression by 2.93-fold (P=0.0001). Similarly, co-treatment with siRNA and vinorelbine produced a substantial 2.89-fold decrease in ABCB1 gene expression in MCF-7 cells compared to that in MCF-7/ADR cells (P=0.0001). Conclusion: The results of the present study indicate that the concurrent use of siRNA and vinorelbine holds substantial promise as a therapeutic approach to overcome ABCB1-mediated multidrug resistance (MDR) in breast cancer. It is necessary to conduct comprehensive clinical trials to determine the true effectiveness of this combination therapy.
Transcending Traditional Treatment: The Therapeutical Potential of Nanovesicles for Transdermal Baclofen Delivery in Repeated Traumatic Brain Injury
Authors: M. Sheta Nermin , A. El-Gazar Amira , M. Ragab Ghada , A. Essa Marwa , M. Abdel-Haleem Khaled , El-Dahmy Rania Moataz
Published: March 2024

Purpose: The repositioning of previously approved drugs is occupying the researchers’ plans. Baclofen (Bac) was our candidate for its established neuroprotective capacity, with a proposal of efficient drug delivery as non-ionic surfactant-based nanovesicles (NISNV) formulae against mild repetitive traumatic brain injury (mRTBI) in rats, thus reducing the number of orally or injected medications, especially in severely comatose patients or pediatrics. Methods: A (23 ) factorial design was implemented for confining Bac-loaded NISNV formulae, where a bunch of variables were inspected. An in-vivo experiment was done to test the prepared formula’s efficacy transdermally. The following parameters were measured: brain expression of gamma amino butyric acid B (GABAB), protein kinase C- α (PKC-α), focal adhesion kinase (FAK), TNF-α and nuclear factor kappa B (NF-κB) p65, malondialdehyde (MDA), superoxide dismutase (SOD), and histopathology. Results: The particle size (PS) and entrapment efficiency percent (EE%) speckled from 60.40±0.28% to 88.02±0.01% for the former and 174.64±0.93 to 1174.50±3.54 nm for the latter. In vitro release% after 8 hours ranged from 63.25±5.47% to 84.79±3.75%. The optimized formula (F4) illustrated desirability=1, with 630.09±3.53 µg/cm2 of Bac permeated over 8 hours, which equates to 100% of Bac. Bac post-trauma treatment restored brain expression of GABAB and PKC-α, while decreasing FAK. Besides enhancing the histological findings, the anti-inflammatory effect was clear by decreasing TNF-α and NF-κB p65. Consequently, significant antioxidant sequelae were revealed herein by diminishing MDA levels and restoring SOD activity. Conclusion: Transdermal delivery of Bac-loaded niosomes confirmed neuroprotection and succeeded in surpassing skin-to-brain barriers, which makes it a promising therapeutic option for repeated traumas.
Recent Advances in Implantable 3D-Printed Scaffolds for Repair of Spinal Cord Injury
Authors: Khaledian Salar , Mohammadi Ghobad , Abdoli Mohadese , Fatahian Arad , Fatahian Arya , Fatahian Reza
Published: March 2024

Spinal cord injury (SCI) is an important factor in sensory and motor disorders that affects thousands of people every year. Currently, despite successes in basic science and clinical research, there are few effective methods in the treatment of chronic and acute spinal cord injuries. In the last decade, the use of 3D printed scaffolds in the treatment of SCI had satisfactory and promising results. By providing a microenvironment around the injury site and in combination with growth factors or cells, 3D printed scaffolds help in axon regeneration as well as neural recovery after SCI. Here, we provide an overview of tissue engineering, 3D printing scaffolds, the different polymers used and their characterization methods. This review highlights the recent encouraging applications of 3D printing scaffolds in developing the novel SCI therapy.
Discovery of a Novel Dual Targeting Peptide for Human Glioma: From In Silico Simulation to Acting as Targeting Ligand
Authors: Sedghi  Aminabad Negar , Saeedi Yousef , Adiban Jamal , Nemati Mahdieh , Shaterabadi Donya , Najafi Farhood , Rahbarghazi Reza , Talebi Mehdi , Zarebkohan Amir
Published: March 2024

Purpose: Receptor-mediated transcytosis (RMT) is a more specific, highly efficient, and reliable approach to crossing the blood-brain-barrier (BBB) and releasing the therapeutic cargos into the brain parenchyma. Methods: Here, we introduced and characterized a human/mouse-specific novel leptin-derived peptide using in silico, in vitro and in vivo experiments. Results: Based on the bioinformatics analysis and molecular dynamics (MD) simulation, a 14 amino acid peptide sequence (LDP 14) was introduced and its interaction with leptin-receptor (ObR) was analyzed in comparison with an well known leptin-derived peptide, Lep 30. MD simulation data revealed a significant stable interaction between ligand binding domains (LBD) of ObR with LDP 14. Analyses demonstrated suitable cellular uptake of LDP 14 alone and its derivatives (LDP 14-modified G4 PAMAM dendrimer and LDP 14-modified G4 PAMAM/pEGFP-N1 plasmid complexes) via ObR, energy and species dependent manner (preferred uptake by human/mouse cell lines compared to rat cell line). Importantly, our findings illustrated that the entry of LDP 14-modified dendrimers in hBCEC-D3 cells not only is not affected by protein corona (PC) formation, as the main reason for diminishing the cellular uptake, but also PC per se can enhance uptake rate. Finally, fluorescein labeled LDP 14-modified G4 PAMAM dendrimers efficiently accumulated in the mice brain with lower biodistribution in other organs, in our in vivo study. Conclusion: LDP 14 introduced as a novel and highly efficient ligand, which can be used for drugs/genes delivery to brain tissue in different central nervous system (CNS) disorders.
The Art of Bioimmunogenomics (BIGs) 5.0 in CAR-T Cell Therapy for Lymphoma Management
Authors: Anurogo Dito , Luthfiana Dewi , Anripa Nuralfin , Fauziah Apriliani Ismi , Soleha Maratu , Rahmah Laila , Ratnawati Hana , Wargasetia Teresa Liliana , Pratiwi Sari Eka , Siregar Riswal Nafi , Sholichah Ratis Nour , Maulana Muhammad Sobri , Ikrar Taruna , Chang Yu Hsiang , Qiu Jiantai Timothy
Published: March 2024

Purpose: Lymphoma, the most predominant neoplastic disorder, is divided into Hodgkin and Non-Hodgkin Lymphoma classifications. Immunotherapeutic modalities have emerged as essential methodologies in combating lymphoid malignancies. Chimeric Antigen Receptor (CAR) T cells exhibit promising responses in chemotherapy-resistant B-cell non-Hodgkin lymphoma cases. Methods: This comprehensive review delineates the advancement of CAR-T cell therapy as an immunotherapeutic instrument, the selection of lymphoma antigens for CAR-T cell targeting, and the conceptualization, synthesis, and deployment of CAR-T cells. Furthermore, it encompasses the advantages and disadvantages of CAR-T cell therapy and the prospective horizons of CAR-T cells from a computational research perspective. In order to improve the design and functionality of artificial CARs, there is a need for TCR recognition investigation, followed by the implementation of a quality surveillance methodology. Results: Various lymphoma antigens are amenable to CAR-T cell targeting, such as CD19, CD20, CD22, CD30, the kappa light chain, and ROR1. A notable merit of CAR-T cell therapy is the augmentation of the immune system’s capacity to generate tumoricidal activity in patients exhibiting chemotherapy-resistant lymphoma. Nevertheless, it also introduces manufacturing impediments that are laborious, technologically demanding, and financially burdensome. Physical, physicochemical, and physiological limitations further exacerbate the challenge of treating solid neoplasms with CAR-T cells. Conclusion: While the efficacy and safety of CAR-T cell immunotherapy remain subjects of fervent investigation, the promise of this cutting-edge technology offers valuable insights for the future evolution of lymphoma treatment management approaches. Moreover, CAR-T cell therapies potentially benefit patients, motivating regulatory bodies to foster international collaboration.
Notch Signaling Suppression by Golden Phytochemicals: Potential for Cancer Therapy
Authors: Kaveh Zenjanab Masoumeh , Hashemzadeh Nastaran , Alimohammadvand Sajjad , Sharifi-Azad Masoumeh , Dalir Abdolahinia Elaheh , Jahanban-Esfahlan Rana
Published: March 2024

Cancer is one of the main causes of mortality worldwide. Cancer cells are characterized by unregulated cellular processes, including proliferation, progression, and angiogenesis. The occurrence of these processes is due to the dysregulation of various signaling pathways such as NF-κB (nuclear factor-κB), Wnt/beta-catenin, Notch signaling and MAPK (mitogen-activated protein kinases). Notch signaling pathways cause the progression of various types of malignant tumors. Among the phytochemicals for cancer therapy, several have attracted great interest, including curcumin, genistein, quercetin, silibinin, resveratrol, cucurbitacin and glycyrrhizin. Given the great cellular and molecular heterogeneity within tumors and the high toxicity and side effects of synthetic chemotherapeutics, natural products with pleiotropic effects that simultaneously target numerous signaling pathways appear to be ideal substitutes for cancer therapy. With this in mind, we take a look at the current status, impact and potential of known compounds as golden phytochemicals on key signaling pathways in tumors, focusing on the Notch pathway. This review may be useful for discovering new molecular targets for safe and efficient cancer therapy with natural chemotherapeutics.
Kavain Alleviates Choroidal Neovascularization Via Decreasing the Activity of the HIF-1α/VEGF-A/VEGFR2 Signaling Pathway and Inhibiting Inflammation
Authors: Chen Xi , Qin Xun , Bai Wen , Ren Junsong , Yu Yang , Nie Huiling , Li Xiumiao , Liu Zhangyu , Huang Jiayu , Li Juxue , Yao Jin , Jiang Qin
Published: March 2024

Purpose: Neovascular age-related macular degeneration (nAMD) is a prevalent cause of blindness in the elderly. Standard treatment includes anti-vascular endothelial growth factor (anti-VEGF) drugs, such as aflibercept. However, anti-VEGF drugs may have limited efficacy and cause drug resistance. This study explores whether Kavain, an anti-inflammatory molecule from Piper methysticum, can treat choroidal neovascularization (CNV). Methods: Various experiments were conducted to assess the Kavain’s toxicity. The impact of Kavain on in vitro cultured endothelial cells was examined through 5-ethynyl-20-deoxyuridine (EdU) assays, transwell migration assays, and tube formation assays. The therapeutic effects of Kavain on CNV were investigated using a laser-induced CNV mice model. To elucidate the mechanism of Kavain, network pharmacology analysis, molecular docking, and western blots were performed. Results: Kavain exhibited no apparent toxicity both in vitro and in vivo. Kavain significantly decreased endothelial cell viability, proliferation, migration, and tube formation ability in a dose-dependent manner compared to the hypoxia groups (P<0.05). Kavain alleviated CNV in the laser-induced CNV mouse model compared to the control groups (P<0.05). These effects were statistically significantly enhanced in the Kavain plus aflibercept groups (P<0.05). Following Kavain administration, the expression levels of various inflammatory factors were markedly reduced in retinal pigment epithelium (RPE)/choroid complexes (P<0.05). Mechanistically, Kavain decreased the activity of the hypoxia-inducible factor 1α (HIF-1α)/VEGF-A/ VEGF receptor 2 (VEGFR2) signaling pathway. Conclusion: Our study is the first to demonstrate Kavain’s potential as a promising treatment for nAMD, owing to its dual effects of anti-inflammation and anti-angiogenesis.
Functionalized and Theranostic Lipidic and Tocosomal Drug Delivery Systems: Potentials and Limitations in Cancer Photodynamic Therapy
Authors: Nasr Esfahani Fahime , Karimi Sahand , Jalilian Zahra , Alavi Mehran , Aziz Bushra , Alhagh Charkhat Gorgich Enam , Mozafari M. R. , Taghavi Elham , Aminnezhad Sargol , Ataei Sara
Published: March 2024

Photodynamic therapy (PDT) is a multidisciplinary area, which involves photophysics and photochemical sciences and plays an important role in cancer diagnosis and treatment. PDT involves a photo-activable drug called photosensitizer (PS), a specific wavelength of light and cellular compounds to produce toxic oxygen species in a much-localized way to destroy malignant tumors. Despite the various benefits of PDT, some PS-related limitations hinder its use as an ideal treatment option for cancer. To address these limitations (e.g., poor bioavailability, weak permeability, hydrophobicity, and aggregation), lipid-based and vesicular drug delivery systems have been employed. These carrier systems possess the ability to enhance the bioavailability, permeability, and solubility of the drug. Furthermore, they tend to load hydrophobic and lipophilic compounds and can be employed for an efficient and targeted drug delivery. The purpose of this review is to highlight the precise idea of PDT, the limitations of PDT related to PS, and the application of lipidic and tocosomal carriers in PDT for the treatment of various types of cancers. Liposomes, nanoliposomes, solid lipid nanoparticles, vesicular phospholipid gels, exosomes, transferosomes, and tocosomes are presented as commonly–employed vesicular drug carriers. Moreover, the amalgamation of cell-based drug delivery systems (CBDDS) with PDT holds considerable potential as an encouraging avenue in cancer treatment, especially in the context of immunotherapy.
Self-perception of digital competences in Higher Education Teachers
Authors: Preza-Medina Sergio Roberto
Published: March 2024

The present study had two research objectives: (a) Analyze the self-perception that higher-level teachers have about the mastery of digital skills in relation to the areas of information, communication, content creation, security and problem solving; and (b) Identify the level of mastery of digital skills presented by higher level teachers in relation to the areas of information, communication, content creation, security and problem solving. The methodological design had a quantitative approach, which allowed the collection of information required to achieve the objectives set. With this study, we contribute to the frontier of knowledge regarding the gaps between the use and application of digital skills, by the teaching staff of public institutions of higher level.
Collaborative activities mediated by technology for integration into University life in the introductory Engineering course
Authors: Macías-Brambila Hassem Rubén , Zamora-Ramos Victor Manuel , Osorio-Ángel Sonia , Becerra-Velázquez Violeta del Rocío
Published: March 2024

The article presents an educational intervention project implemented in the Introduction to Engineering subject of the Computer Engineering Educational Program of the Centro Universitario de Ciencias Exactas e Ingenierías of the Universidad de Guadalajara, developed by the Investigation Groups UDG-CA-991 Desarrollo de Competencias Profesionales en Ciencias Computacionales and the UDG-CA-863 Gestión y Desarrollo de Competencias en Entornos Virtuales during the periods 2022-B and 2023-A which developed strategies that integrated actions and resources for collaborative work mediated by technology for the integration of students into the university life, under a mixed model and a section group as a sample, achieving a pedagogical proposal assisted by technology focused on the development of significant learning, in which an impact evaluation was applied with interview and survey instruments, as well as satisfaction and evaluation , considering the institutional, teacher and student dimensions or categories. The project was focused with the principles of continuous improvement.
Technology applied in inventory control, case study: Department of measurement, connections and services of the Federal Electricity Commission
Authors: Valdez-Guerrero Raquel , Barboza-Morales Suguey , Robles-Arias Isela Margarita , Ríos-Calderón Graciela Guadalupe
Published: March 2024

The use of technology represents making processes more efficient and obtaining better results in their control. For government institutions such as the Federal Electricity Commission, it represents benefits in the optimization of resources and improvements in the services provided to the users of the organization, likewise it implies savings due to the good performance in the use of the materials that uses this department, focused on providing services to users, since costs are lowered. The study has been carried out through a diagnosis to know the real causes of the problem in the area, various instruments have been used to collect information to later process through tools that allow us to know the root cause of the problem. The analysis was carried out through the SWOT matrix to find opportunities for improvement, to end with the strategic proposal as well as the relevant actions, and the importance of having a contingency plan that allows controlling the strategic actions designed.
Gunshot detection neural network implemented on a low-cost microcontroller
Authors: Rodríguez-Ponce Rafael
Published: March 2024

Nowadays, criminal activity is on the rise, and it usually involves some type of firearm. There are automated shot detection systems but in the end, they still require human intervention to decide if it is an actual gunshot. Distinguishing between two similar sounds, such as the detonation of a firearm or a firecracker, is not always possible with the naked ear. There are multiple publications on artificial intelligence to identify gunshots; however, they use convolutional neural networks, which, despite being highly effective, require a system with extensive computational resources. This document presents a fully connected neural network implemented on a microcontroller that can identify up to 90% of firearm detonations. This document will be of interest to students or researchers interested in the design of neural networks for sound recognition on embedded systems.
Implementation of Matlab communication and Allen Bradley PLC for control of the AMATROL JUPITER XL Robot
Authors: Hernández-Jiménez Samuel Abinadí , Ortiz Vázquez Jonathan , Ortiz-Simón José Luis , Cruz-Hernández Nicolás
Published: March 2024

The article introduces a method to enable a robot, the "AMATROL JUPITER XL," without relying on its conventional controllers. Instead, a Human-Machine Interface (HMI) is employed using Allen Bradley's "ControlLogix 5550" software. This setup combines the engineering program MATLAB (via the Simulink extension) to develop control block diagrams containing calculations for robot design and comprehension. A data read-write interface is implemented on an "Allen Bradley 1756-L1" PLC, along with the integration of an Open Platform Communication (OPC) platform using the "RSLinx Classic" software. This configuration empowers the user to manipulate trajectories and objectives using calculations that depict the kinematics and dynamics of the mentioned robot. Consequently, this setup offers a control option that enables direct application of theoretical mathematical principles to the design and control aspects of robotics, leading to enhanced understanding of these principles.
Transfer Learning to improve the Diagnosis of Type 2 Diabetes Mellitus (T2D)
Authors: Cutié-Torres Carmen , Luna-Rosa Francisco Javier , Luna-Medina Marisol , Dunay-Acevedo Cesar
Published: March 2024

Transfer Learning is a Deep Learning technique that is currently being used in early and non-invasive diagnosis of T2D. The objective of this work is to design and implement a Transfer Learning model trained with images of skin patches belonging to healthy people and diabetic foot patients. The research methodology was constituted by 3 phases (Analysis and Design, Development and Evaluation) composed of 5 steps that comply with the proposed objective. Several convolutional neural network (CNN) models were developed: CNN built from scratch, AlexNet, CNN with data augmentation technique, FE-VGG16, FE-ResNet50 and FT-VGG16. These models were evaluated using a set of metrics derived from the confusion matrix, the Receiver Operating Characteristic curve (ROC) of each model and the value corresponding to the area under the curve (AUC). The best performance corresponded to FT-VGG16 model that fuses VGG-16 pretrained model with a block of fully connected layers. Finally, satisfactory results are reported and allow us to conclude that the application of Transfer Learning models for the classification of diabetic foot images constitutes a viable tool for the non-invasive diagnosis of T2D.
Annual Forecast of Photovoltaic Power Generation Based on MLP Artificial Neural Networks
Authors: Garcia-Hernandez Martin , Reyes-Amezcua Ivan , Rodriguez-Armenta Jeronimo , Garcia-Garcia E. Xio Mara
Published: March 2024

The intermittency of solar energy resources presents a significant challenge in balancing power generation and load demand. To enhance system consistency, forecasting photovoltaic solar energy is crucial. Among numerous techniques, Artificial Neural Network (ANN) is an efficient tool that can help simplify this problem and predict photovoltaic power generation based on various inputs such as weather data and panel characteristics. In this paper, we present the results of an annual forecast of photovoltaic power generation based on Multilayer Perceptrons (MLP), which provides valuable insights into the potential of MLP ANN for accurate and reliable prediction of photovoltaic power generation, thereby improving the efficiency and reliability of photovoltaic systems. The results were obtained based on data collected over a year and validated with data from the following year. Mean Squared Error (MSE) was utilized to quantify the error between the predicted and measured photovoltaic solar energy generation. The analysis demonstrated that this annual forecast of photovoltaic power generation is highly accurate.
Barcode system applied to medical prescriptions
Authors: Jara-Ruiz Ricardo , Quezada-Muñoz Marcos Emmanuel , Delgado-Guerrero Sergio Humberto , García-Rodríguez Juan Carlos
Published: March 2024

In this paper the results and methodology for development of a barcode system applied to health sector are showing. The project main objective is generating medical prescriptions with a barcode to make the medicine identification assigned by the specialist easier and optimize the issuance process for the patient. It is necessary to access a database of basic plan medications to generate the physical document of the medical prescription. The previous information as a first project stage, considering to the future linking this system to automatic medicine dispenser devices install in different spaces into health institutions and public areas and thus, reduce the waiting times and avoid the spaces saturation for expand the access to these services to entire population.
Optimization in the Warehouse Area Through the 5s Methodology
Authors: Venegas Arista Jocelyn Isabel , Rendón-Maldonado Marcos Felipe , Torres-Cruz Hector
Published: March 2024

Goals: Optimize the company's warehouse area using the 5S methodology; Reduce to the maximum, the time wasted in search of the necessary tools when carrying out any type of work; Increase the space or useful area in the company's warehouse; Keep existing material and the right tools in the right place. Methodology: The qualitative approach of the 5S method involves the observation and detailed analysis of processes and work spaces to identify opportunities for improvement in terms of organization and cleanliness. It is a methodology that seeks to understand the user experience and how it relates to their work environment, in order to design solutions that suit their needs. The qualitative approach of the 5S method seeks to improve the quality of life and satisfaction of workers, which in turn can have a positive impact on productivity. Investigation: What is the 5S methodology?; What is the impact of good warehouse management within a company?. Contribution: It was possible to organize and assign a space for each tool, obtaining with this the reduction of time in the search for tools and materials in the warehouse area.
Implementation of the dual system within the TSU career in Design and Industrial fashion, production area
Authors: Ramírez-Mondragón Xóchitl , Tenorio-Lara Raúl , Vázquez-Juárez Yolanda
Published: March 2024

This work shows the learning process in which you work at the same time or at the same time, the learning acquired at the university with the work in the company, that is, the knowledge acquired in your academic stay and the relationship of the different areas. work assigned in the labor field, calling it this way, dual system, it is worth mentioning that the student is assigned an academic advisor (teacher or tutor) by the university and a business advisor assigned by the beneficiary company (manager, manager, coordinator), in this way the student has the attention of both parties, strengthening academic and work learning, it is worth mentioning that the change of area in its periodicity or temporality is assigned by consensus between the business advisor and the academic advisor, so the same way the areas to assign, by means of a work plan where it is established at the beginning of the student's stay in the company.
Monthly Workshops: The Importance of Practice in the Professional Development of Students
Authors: González-Garza Erick Arturo , Aguilar-Pachecano Gloria Leticia , Castillo-González Arianna Iveth , Vázquez-Loredo Perla Lizeth
Published: March 2024

This article aims to explain the importance of practical experience in the professional development of students of the Higher Technician of the English Language program, from the Universidad Tecnologica Cadereyta, in Nuevo Leon, through a monthly activity called "Mañanas de trabajo". As a result, this activity has favored the strengthening and integration of the skills and competencies promoted by the study plan, in the professional training of the students of the career, especially in the teaching of the English language; furthermore, “Mañanas de trabajo” has allowed the interaction of university students with schoolchildren of the different levels of basic education, through various activities that are carried out throughout this monthly exercise in the classrooms and various spaces on the university campus. Therefore, the importance of meaningful learning is considered, through the different practices that are generated, above all, the impact on the integral formation of students in the educational area.
Culture of data protection, service and quality is cybersecurity in SMEs
Authors: Peña-Montes De Oca Adriana Isela , Mondragón-Gutiérrez Einar
Published: March 2024

The purpose of this paper is to develop a strategic model to establish the best cybersecurity mechanisms and standards, mediating the protection and care of product and service information, emphasizing the importance of creating a culture of data care in order to deal with the challenges of global competition. A methodology was develop integrating tools such as PMI, SDLC, Kaizen and NIST framework, in order to establish responsibilities scope, times and resources, acquiring or adapting existing resources. The proposed model makes efficient use of Internet tools and new technologies to guarantee sustainability, cybersecurity, speed, flexibility, privacy of the information processed and energy backup, in order to promote change in favor of the development of competitive advantages in SMEs. The results allowed, through a collegiate work between the members of the interdisciplinary team, the construction of a Cybersecurity Model that supports SMEs, better safeguarding the data, although with a residual risk associated with routines due to updates and/or needs changing.
Implementation of the Organizational Culture in the Paletería la Michoacana
Authors: Reyes-Martínez Lucia , Vicuña-Tapia Hérendira , Palma-Bermejo Yetzabel
Published: March 2024

The study of organizational culture represents a complex pattern of beliefs, expectations, ideas, values, attitudes and behaviors shared by the members of an organization, which evolves over time. Specifically, organizational culture includes: Routine ways of communicating, such as organizational rituals and ceremonies and common language; the norms shared by individuals and teams throughout the organization; the dominant values held by the organization; the philosophy that governs the organization's policies and decision making; the rules of the game for getting along in the organization or the "tricks" a newcomer has to learn to become an accepted member; the feeling or climate conveyed in an organization by the physical layout and the way members interact with customers, suppliers and other external parties. In this work the need for an approach to Organizational Culture in the microenterprise Peletería la Michoacana is based, where the concepts are taken and illustrated with results in a practical case, with the General Objective of implementing in the Peletería la Michoacana a corporate culture, which transmits a sense of identity to the members who belong to the organization, and facilitates the generation of commitment to something bigger than individual interest. Specific objectives: To define boundaries or create differences between an organization and others; To be a company that gives meaning and control to guide and shape employees' attitudes and behavior. Organizational culture provides the ability to act strategically and efficiently through business values. These indicate the way in which the different business needs can be solved, as well as the direction that all members of the company will follow.
Switchable emissions of an Erbium-doped fiber laser using cascaded MZIs based on CHCF
Authors: Herrera-Piad Luis , Velazquez-Gonzalez Felipe , Duran-Perez Oscar , Brianza-Gordillo Gerardo
Published: March 2024

In this work, a single and dual-wavelength erbium-doped fiber laser (EDFL) based on two Mach-Zehnder interferometers (MZIs) in cascade structure was experimentally validated. MZIs were assembled by joining a capillary hollow-core fiber (CHCF) piece between two multimode fibers (MMFs) sections. The switchable operation is reached by moving the spectrum of one MZI when the temperature is increased. The maximum measured signal noise to ratio (SNR) was more than 50 dB for the single and dual-wavelength laser lines. Besides, stable output is shown since no power and wavelength variations were noticed. It is important to mention that emissions are obtained at precise wavelength positions and not arbitrarily as described by other investigations. This EDFL can be used in applications of optical fiber communications systems and fiber sensing.
Identification of an instrumental proposal based on fiber optic sensors of the Bragg grating type for implementation in an experimental platform for dynamic analysis
Authors: Hernández-González Josué Iván , Torres-Cedillo Sergio Guillermo , Hernández-Moreno Hilario , Cortés-Pérez Jacinto
Published: March 2024

Recently it has been reported the use of non-invasive methods for the identification and monitoring of vibrational parameters in rotodynamic systems, such as aircraft engines, which require the implementation of innovative detection systems, such as fiber optic sensors, which overcome deficiencies of adaptability to adverse environments such as intense magnetic fields and the impossibility of performing a distributed detection of vibrations, limitations present in the sensors conventionally based on capacitive or piezoelectric principles. Therefore, in the present study, through the use of an experimental platform for dynamic analysis, the best proposal of an instrumental system based on fiber optic sensors with Bragg gratings was selected for its use in vibrational measurement and analysis, through the theoretical study of the different approaches to vibrational analysis using fiber optic sensors with Bragg gratings. The analysis of the results of the study presents a justification of the type of instrumental proposal selected from the characteristics provided by the experimental platform. In addition, the experimental proposal will be implemented in the future and may contribute to the development of other vibrational studies.
Processing and recognition of EMG signals through CNN networks for the control of electric vehicles
Authors: López-Rodríguez Pedro , Montiel-Rodríguez Martin , Samano-Flores Yosafat Jetsemani , Mandujano-Nava Arturo
Published: March 2024

The increase in autonomous driving technologies, as well as biometrics using biosignals from vehicle drivers, provide information that can be used for the development of personalized biosecurity and driving systems for each user. Currently, studies are being carried out on the extraction and classification of driver characteristics with great precision, to generate intelligent systems that are auxiliary and that help to safeguard the integrity of people while driving vehicles. This work presents the recognition of 5 hand gestures to control the driving actions of an electric vehicle using the EMG signals from the MYOTM bracelet, these signals have also been used to detect users and thus allow the use only of the people registered in the application. To perform gesture recognition, a convolutional neural network was trained and implemented for the classification of actions. Finally, a cross-validation was carried out to validate the reliability of the proposed system, obtaining 99.2% accuracy during the classification.
INDICATIONS OF UNFAIR BUSINESS COMPETITION IN DETERMINING AIRCRAFT RATES ASSOCIATED WITH LAW NUMBER 5 OF 1999 CONCERNING MONOPOLY AND UNFAIR BUSINESS COMPETITION (CASE STUDY OF KPPU KANWIL IV SURABAYA)
Authors: Syaiful Muhammad , Waluyo
Published: March 2024

This study intends to find out the legal norms for the behavior of airlines in setting very low prices for scheduled domestic commercial airline tickets with the aim of eliminating competitors in the same class and the same route based on the perspective of Law No. 5 of 1999 concerning the Prohibition of Monopolistic Practices and Unfair Business Competition , and describes the obstacles experienced by the Commission for the Supervision of Business Competition (KPPU) which has the authority to supervise and investigate this case. This study uses the Juridical Empirical Research method and concludes that by eliminating the rules regarding the requirements for adding flight frequencies that can be carried out by airlines on one route, it creates gaps for airlines with a larger fleet advantage to be able to carry out selling and loss practices, namely by setting fares lower than its competitors but with a greater number of flying frequencies causing a decrease in the competitiveness of these routes, this is clearly not in accordance with the rule of reason for the issuance of the Law on Anti-Monopolistic Practices which aims to increase competition in the market and pay attention to the balance between business actors and the constraints experienced by KPPU as the competent authority in this case is that there are no rules regarding the option of forced summons that can be carried out by the KPPU in order to present the reported party in the framework of investigating a case which results in a delay in completing the case
VIRTUAL ETHNOGRAPHY OF @DAILYHOTELS.ID ACCOUNT AS A HOTEL PROMOTION MEDIA IN INDONESIA
Authors: Shafa Aliyya Sausan , Achmad Zainal Abidin
Published: March 2024

Content management is planning and managing content uploaded on social media that can support promotional activities. This study aims to understand content management strategies to help promotional activities by the @dailyhotels.id account. This study uses a qualitative method with a virtual ethnographic approach. Data collection in this study used virtual searches and interviews with six informants: one account owner @dailyhotels.id, one admin @dailyhotels.id, and four followers @dailyhotels.id. The results of the study show that the content management strategy can help the process of promotional activities for hotels in Indonesia by @dailyhotels.id to have an impact on promotional activities and create purchasing decisions for potential customers. Furthermore, @dailyhotels.id conducts content management to support promotional activities by interacting with @dailyhotels.id followers. In this study, it can be concluded that the content management strategy can help the promotion process be effective and convey information about hotels that the public does not know widely.
THE READINESS OF ELEMENTARY SCHOOL TEACHERS IN IMPLEMENTING THE INDEPENDENCE CURRICULUM
Authors: Widyawati Nur , Mudiono Alif , Arifin Slamet
Published: March 2024

ABSTRACT

This study aims to describe (1) teachers' understanding of independent curriculum policies, (2) teachers' readiness in formulating learning objectives of the Pancasila profile, (3) teachers' readiness in implementing 21st century learning, and (4) teachers' readiness in identifying students' potentials. The research design uses surveys and needs analysis. The study population consisted of 40 elementary school teachers in cluster 4 of Nglegok District, covering 5 institutions. The sample is determined using a random technique. Data collection techniques used questionnaires and interviews with teachers and principals. The results showed that the teachers understood (1) the essence of the independent curriculum policy, (2) how to formulate learning objectives for Pancasila student profiles, (3) how to implement 21st century learning, (4) the concept of identifying various kinds of student potential. The recommendations from the results of this study are: teachers need reinforcement in understanding learning outcomes in the independent curriculum, how to develop learning paths and objectives, steps for preparing school operational curricula, and implementing projects to strengthen Pancasila student profiles.

 

Keyword: Elementary School Teacher Readiness, Implementation of the Independent Curriculum
IMPLEMENTATION OF POLICE DISCRETION IN CRIMINAL LAW ENFORCEMENT IN ANARCHIC DEMONSTRATIONS
Authors: Siregar Salwa Ramadhani , Mahanani Anajeng Esri Edhi
Published: March 2024

Police discretion is the authority of members of the police to take a policy in certain situations that require their own judgment as long as it does not violate statutory provisions. It aims to guard, maintain order and ensure public security. However, policies issued often raise pros and cons, especially when enforcing criminal law in securing demonstrations. The community considers that the actions taken are a form of hindering the achievement of their aspirations. This condition eventually led to riots during demonstrations which could threaten the safety of the demonstrators, police officers, as well as those at the location of the action. So that in this situation police discretion can be issued to prevent and deal with various threats that occur. This study uses an empirical juridical method, namely direct research conducted by studying the applicable legal rules with real events that occur in society. The results of this study explain related considerations, procedures, to obstacles and efforts made in the application of discretion by members of the police in overcoming anarchic demonstrations
BELOPTERA LONGA NAEF, 1922 (CEPHALOPODA: COLEOIDEA) FROM THE LATE EOCENE (PALAEOGENE) OF UKRAINE
Authors: Dernov Vitaly
Published: March 2024

Beloptera longa Naef, 1922 and Beloptera aff. longa Naef, 1922 have been described from the Priabonian Mandrykivka Beds of the Rybalsky Quarry Konzentrat-Lagerstätte in addition to previously known Beloptera belemnoidea de Blainville, 1825, B. cf. longa Naef, 1922, Belosaepia blainvillei (Deshayes, 1835) and Vasseuria occidentalis Munier-Chalmas, 1880. The geographical and stratigraphic distribution of the species Beloptera longa, which was previously recorded only in the Bartonian of England, has been expanded. Cephalopod assemblages from the Priabonian of Ukrainian consist of the genera Beloptera, Vasseuria, Belosaepia, Aturia and Eutrephoceras.
Ideology in the text of the Caucasian chalk circle
Authors: Abdel Zahra Muhammad Muhammad
Published: March 2024

إذا كان النقد المسرحي قد حكمته وظائف متعددة تراوحت في أغلبها بين وصف العمل المسرحي وتفسيره ، أوتجاوز ذلك إلى تقييمه والحكم عليه ، مع الحرص على القيم التي تقتضيها استجابة الفن لتطلعات المجتمع ، وما يستدعي ذلك من قيام بدور التوجيه والإرشاد ، فإن النظر إلى العمل المسرحي من خلال هذه المستويات ، بحثا ودراسة وتنظيرا ، لم يكن كفيلا بحل إشكالية الإيديولوجي والجمالي في النقد والقراءة ، بل كثيرا ما تعمقت إشكالية القراءة بسبب تركيز الناقد على جانب من العمل المسرحي دون سواه ، مما جعله يتسم بالجزئية والسطحية . ومنذ أواسط القرن العشرين ظهرت طروحات ( برتولد بريخت ) ، باعتبار الأيدلوجيات وعاء فكري واجتماعي الذي يبلور أطر الصراع في الحياة و الدراما ، فكان أبرز منظر للمسرح بعد( أرفن يسكاتور) ، بما تنطوي قراءاته الأيديولوجية للنص المسرحي على عنصر ذاتي يغلِّب إرادة المصلحة ، اوإرادة السلطة والرغبة في تحقيق الأهداف الخاصة على إرادة المعرفة. فقد ارتبط مفهوم القراءة الأيديولوجية بالصراعات الاجتماعية والسياسية ، في إطار نظرية اجتماعية و تاريخية واحدة . بهذا ذهب البحث الى الفرضية الاتي : ما هي القراءة الايديولوجية التي ظهرت في مسرحية بريخت ( دائرة الطباشير القوقازية ) انموذجاً . وبهذا تكون البحث من الإطار المنهجي وهدف ، ومن الاطار النظري بمبحثين - المنهج الايديولوجي في النقد ، و القراءة للايديولوجية في المسرح ، وخرج الى ما أسفر عنه الإطار النظري وفيما تضمن الفصل الثالث : استعراضا للإجراءات التي أخذت لغرض تحقيق هدف البحث . فقد أستخدم الباحث الطريقة الوصفية التحليلية للتوصل إلى النتائج . وتبلورت ايديولوجيات القراءة للافكار الاشتراكية في نص دائرة الطباشير بوصفها سلطة عقلانية جديدة ، لا تستكين عند ثابت معين ، بل تغيير ديناميكي مستدام ومتداول من مرحلة إلى أخرى في اطار المالك والمملوك . كما ظهر في اطار الاستنتاجات أن الجدل الماركسي عند بريخت مرتبط بفكرة العقل ، أو هو حوار العقل مع ذاته في القراءة الايديولوجية ، أما موضوعه فهو الفكرة الشاملة للوعي الإنساني ، بوصفها قوة مبدعة كلياً لكل ما هو في النص