bluuebunny/crossref_metadata_2025 huggingface dataset:
Perception of Science Teacher Candidates Towards Cultural Literacy
Authors: Wazni M. Khairul , Muliadi Agus , Sarwati Sarwati
Published: December 2023

This study aims to describing the perception of science teacher candidates toward cultural literacy. This study is an exploratory research with 61 biology education students as subjects, comprising 28 from the Biology Education program at Mandalika University of Education, 16 from Hamzanwadi University, and 17 from Mataram State Islamic University. The research instrument used was a closed questionnaire with degraded answers according to a Likert scale that had been declared valid. Analysis of research data used is descriptive statistics and inferential statistics with Anova test at a significance level of 5%. The results of the study show that (1) average score of student perceptions regarding cultural literacy, namely, students from Mandalika University of Education have an average score of 2.86 in the Good category, students from Hamzanwadi University have an average score of 2.58 in the Good category, and students from Mataram State Islamic University have an average score of 2.64 in the Good category.; (2) there is a significant difference in the perception of students at Mandalika University of Education, Hamzanwadi University, and Mataram State Islamic University regarding cultural literacy, as evidenced by a significance value of 0.030 is smaller than the alpha testing value of 0.05 (<0.05).
Perancangan Tekhnologi Pengolahan Limbah Sekam Padi Pada kelompok rampahdone Farm Dalam Mendukung Ketahanan Pangan Pada Masyarakat Desa Wanasigra Kecamatan Sindangkasih
Authors: Tirto Madawistama Sri , Ni’mah Khomsatun , Heryani Yeni , Kurniawan Dian
Published: December 2023

Chaff waste which has no economic value will become of high value after being converted into rice bran through the milling process. Rice bran is very much in demand because it provides many benefits. The abundant and abundant availability of husk waste and only being left and burned is of course a problem due to the lack of information on utilizing this waste. By processing rice husk waste, it can be used as animal feed for boiler chicken and free-range chicken rations for residents who have poultry such as chickens. Furthermore, bran which is a by-product of the rice milling process can also be a staple food with high nutritional value. Bran has a high nutritional content, and so far only often used as animal feed can also be consumed with various properties, such as having a high content of B vitamins namely thiamine, niacin and B6 which play an important role in energy production, cardiovascular health and preventing depression It is also considered as a source of natural fiber. In order to be able to utilize the abundant rice husk waste, an appropriate technology design is carried out in processing rice husk waste in the Wanasigra village community into various alternative results of processing this waste to support food security. The results and outputs of community service activities for the food security scheme (PBM-KP) for the Wanasigra Village community, namely residents becoming more independent, residents can maintain the food security of their families, residents and farmer groups gain knowledge through coaching and counseling in utilizing the results from the design of rice husk waste processing technology , providing assistance to target partners to be more independent in processing rice husk waste, food availability, earning additional income for their families. The method used in the service is through counseling, discussion, mentoring and introduction and design of technology to marketing through agricultural experts appointed by external parties. Sales are facilitated by the appointed chairman to distribute to other areas outside the Wanasigra village.
Pelatihan Penulisan Karya Tulis Ilmiah untuk Memotivasi Literasi Menulis Siswa MTsN 1 Mataram
Authors: Utama Alfian Eka , Marhani  , Satriyantara Rio , Anggraeni Dara Puspita , Dewi Irma Risvana
Published: December 2023

Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk memberikan pengetahuan, pemahaman serta pengalaman untuk meningkatkan motivasi peserta didik tentang penulisan karya tulis ilmiah, karena selama ini di MTsN 1 Mataram hanya sekedar melakukan pendampingan pada saat kompetensi karya tulis ilmiah saja. Karya tulis ilmiah yang merupakan salah satu literasi menulis peserta didik merupakan keterampilan yang sangat penting diera saat ini, sehingga kampuan tersebut perlu dimiliki oleh peserta didik guna menunjang pendidikan di sekolah maupun ketika nanti melanjutkan ke jenjang perguruan tinggi. Kegiatan pelatihan ini meliputi penjelasan materi tentang kaidah-kaidah penulisan karya tulis ilmiah, cara memunculkan ide kreatif kedalam sebuah tulisan serta cara mencari sumber tulisan yang baik untuk karya tulis ilmiah. Kegiatan ini diikuti oleh 45 peserta didik dari kelas VII, VIII, dan IX MTsN 1 Mataram. Metode kegiatan ini ada tiga yaitu pra pelatihan, pelaksanaan pelatihan dan evaluasi pelatihan. Hasil yang diperoleh dari kegiatan ini menunjukkan bahwa pelatihan yang diberikan cukup memotivasi dan meningkatkan keterampilan siswa untuk menulis karya ilmiah.
To determine the frequency of Baker’s cyst on MRI in patients with knee pain.
Authors: Mariam Yamin  , Kahkashan Hameed  , Kelash Kumar  , Mahesh Kumar  , Nazia Azeem
Published: December 2023

Objective: To determine the frequency of Baker’s cyst in patients presenting with knee pain, considering MRI as imaging modality. Study Design: Descriptive, Cross-sectional study. Setting: Department of Radiology, JPMC, Karachi. Period: 03 January 2021 till 02 July 2021. Material & Methods: Total 113 patients presenting with knee pain for >4 weeks duration who were referred for knee MRI were selected in the study. Both male and female patients between 15-65 years included in the study. Post-surgical patients and those with contraindication to MRI were excluded from the study. MRI of effected knee was performed in every selected patient by using 1.5 Tesla MRI by placing the knee in extended position with slight external rotation to facilitate imaging. MR images were interpreted by one consultant radiologist for presence or absence of Baker’s cyst. Results: Patients of 15 to 65 years age were included in the study with mean age of 44.94 ± 6.69 years. Out of 113 patients, 65 (57.52%) were male and 48 (42.48%) were female with male to female ratio of 1.4:1. Mean BMI of patients was 27.45 ± 3.02 kg/m2. Mean duration of pain was 5.78 ± 2.30 months. In our study, 22 patients with knee pain were found to have Baker’s cyst on MRI with frequency of 19.47%. Conclusion: This study concluded that frequency of Baker’s cyst on MRI in patients with knee pain is quite high.
Tube Laparostomy as Initial and Sole Intervention for Neonates with Idiopathic Pneumoperitonium.
Authors: Roshan Ali  , Nabi Bux Napar  , Ishrat Mahtam  , Farah Mahar  , Sirajuddin Soomro  , Noor Ahmed
Published: December 2023

Objective: To determine the efficacy of tube laparostomy an initial and sole surgical intervetion in neonates diagnosed with idiopathic pneumoperitonium. Study Design: Retrospective study. Setting: Department of Pediatric Surgery, Ghulam Muhammad Mahar Medical College Sukkur and Department of Pediatric Surgery, Chandka Medical College Larkana. Period: 1st April 2020 till 30th March 2023. Material & Methods: Tube laparostomy was done in Operation Theater under local anesthesia in all neonates with pneumoperitonium. After the procedure all patients were kept in neonatal intensive care unit for close observation. Patients draining gut contents in the drain underwent exploratory laparotomy while who clinically improved with only serous discharge in the drains and recovered smoothly were labeled as cases of idiopathic or benign pneumopertonium. Data was collected that included, age, gender, weight, efficacy of the procedure, need to do exploratory laparotomy, post-operative pain scores assessed with the help of neonatal infant pain assessment, total hospital stay length and mortality. Results: A total of 178 cases of neonatal pneumoperitonium were diagnosed during the study period. Out of these 178 cases only 23 (12.92%) were labelled as idiopathic pneumoperitonium on the basis of absence of gut contents in the drainage. Out of these 23 cases, 22 (95.65%) were successfully treated with laparostomy and one case was proceeded with exploratory laparotomy. Post procedure NIPS score remained low and favorable with mean and standard deviation of 1.83±1.4. Total length of hospital stay ranged from 4 days to 15 days. Mean and standard deviation of hospital stay was 6.22±2.8 days. Conclusion: It is concluded in our study that tube laparostomy in cases of idiopathic pneumoperitonium is very efficacious treatment option. This procedure is is easy to do, can be safely done in critically ill patients, can be done under local anesthesia, results in lesser post-operative pain scores and reduces the hospital stay length and cost of treatment.
PERSAINGAN USAHA TIDAK SEHAT ANTAR ONLINE SHOP DALAM KONDISI COVID-19 TERHADAP KEBIJAKAN YANG DIKELUARKAN OLEH PRESIDEN
Authors: Agustina Meria
Published: December 2023

In this digital era full of advancement in technology, who is not familiar with the term of online shopping. Nearly the majority of society has taken advantage of today's technological sophistication. The need for online shopping is accommodated by the large numbers of e-commerce sites that have sprung up. Especially since there is a pandemic spread of 2019 Corona Virus Disease or better known as Covid-19. The spread of Covid-19 in Indonesia is also increasing every day, up till now, suspected cases of Covid-19 have been found in 18 provinces. The impact of the panic in the community can be seen through the price of health products such as hand sanitizers which rose unnaturally in online shops. Considering this, there is a lot of competition happens between online shop businesses. Therefore, the writer is interested in analyzing the business competition related to online shops which will affect the stability of the economy in Indonesia, especially, with the consideration of the effects of Social Distancing policy applied by the Government.
Peran Masyarakat Adat Dalam Menjaga Kawasan Ekoregion Danau Lindung Di Desa Nanga Empangau Kecamatan Bunut Hilir Kalimantan Barat
Authors: Lestari Nina Niken , Anshari Anshari
Published: December 2023

Interaksi manusia dengan alam sekitar seringkali mengorbankan alam itu sendiri. Sebagai penopang kehidupan manusia, kekayaan alam baik sumber-sumber daya alam dimanfaatkan sebebas-bebasnya dan sebesar-besarnya. Seakan tak memiliki aturan yang membatasi perlakuan manusia terhadap sumber daya alam tersebut, manusia berlomba-lomba membangun infrastruktur wilayah namun abai terhadap eksistensi keberadaan kekayaan alam. Beruntung masih ada segelintir masyarakat yang hidup berdampingan langsung dengan akses sumber daya alam tersebut memiliki kesadaran terhadap pelestarian Kawasan sumber daya alam dengan melahirkan aturan-aturan yang bersifat kearifan local guna mengendalika interaksi perilaku manusia terhadap alam lingkungan sekitar guna keberlangsungan kehidupan masyarakat itu sendiri agar tertib dan ramah dalam mengelola sumber daya alam maupun menjaga dan melestarikan alam sebagai makhluk hidup yang perlu dirawat keberadaannya.
Self Efficacy of Prospective Mathematics Teacher on Numerical Literacy Based on Lesson Study
Authors: Fadiana Mu'jizatin , Nikmah Afifaftun , Hasan Abdul
Published: December 2023

One of the instruments used in National Assessment is Minimum Competency Assessment. In this assessment, there are two types of competencies that are measured, they are reading literacy and numeracy literacy. In the process of developing numeracy literacy skills for students, one of the determining factors is the teacher. The purpose of this study was to describe the self-efficacy of prospective mathematics teacher students towards numeracy literacy in lesson study-based learning activities. This research was conducted at Mathematics Education Study Program, PGRI University of Ronggolawe in 2021/2022 academic year. The subjects in this study were 28 students who were taking Ethnomathematics courses. The instrument used is an observation sheet and a self-efficacy scale on numeracy literacy. The research method used is lesson research with lesson study which has three stages in each cycle, namely plan, do and see. The research was carried out in 3 cycles. Based on the data analysis, it was found that the students' self-efficacy towards numeracy literacy was mostly in the medium category.
Analysis of the Role of Parents Role in Home Numeracy
Authors: Anggraini Gina , Lidinillah Dindin Abdul Muiz , Apriani Ika Fitri
Published: December 2023

The purpose of this study is to find out how the activities and roles of parents towards numeracy learning at home are reviewed based on parents with different types of jobs. The research method used is descriptive qualitative research. Data was collected using a questionnaire guideline which includes counting activities at home done with the mother, interview guidelines as clarifying material from the questionnaire which contains counting activities done with the mother and the media used. The results showed the role of (1) parents who work as entrepreneurs have played a good and compact role in providing facilities that support counting activities at home, (2) parents who work as self-employed are quite good at providing facilities for counting activities at home, this is because parents are less compact and less involved in the process of children learning to count at home, (3) while parents who work as teachers have played a very good role in providing facilities for counting activities at home, and always provide motivation. This shows that parents' awareness is an important point in teaching counting at home.
The Effect of Model Discovery Learning on Students’ Self-Efficacy and Student Learning Outcomes
Authors: Febriana Rina , Putri Prihastini Oktasari , Delyana Hafizah
Published: December 2023

One of the factors that influences a person's level of success in the learning process is self-efficacy. Low self-efficacy and student learning outcomes in the learning process are the background for this research. In order for student self-efficacy and learning outcomes to increase, there needs to be a learning process that makes students learn meaningfully, one of which is the model discovery learning. The purpose of writing the article is to see whether there is an increase in student self-efficacy after implementing the discovery learning model and whether there are differences in learning outcomes between the application of the model discovery learning and student learning outcomes using the scientific approach. The method in this research uses experimental research methods with research instruments in the form of questionnaires given to students before and after the learning process using discovery learning models and learning outcomes tests. Based on the calculations, it was found that there is an increase in students' self-efficacy after applying the model discovery learning, with a value  of 0.43 categorized as a "moderate" improvement. This indicates that the discovery learning model positively contributes to enhancing students' self-confidence. This means that there is an increase in student self-efficacy by implementing the model discovery learning. For student learning outcomes, the calculation results obtained are 𝑡ℎ𝑖𝑡𝑢𝑛𝑔 = 2.38 and 𝑡𝑡𝑎𝑏𝑒𝑙 = 1.67. This means that student learning outcomes by applying the model discovery learning are better than by applying learning using the scientific approach.
Nation-Building Through Imperial Images
Fragility and Charisma of Emperor Meiji’s Public Persona
Authors: Cărbune Maria
Published: December 2023

This article explores the complex construction of Emperor Meiji’s public image, from a calculated fragility that promoted national unity to the projection of modern imperial charisma. It examines the extensive Meiji period regime of censorship of imperial representations in various forms, such as portraits, photographs, statues, and currency. The fact that the Emperor was forbidden to compose love poetry and the highly selective publication of his poems during his lifetime likewise emphasises the state’s control over the imperial persona and paints a vivid picture of the multifaceted image-crafting efforts surrounding Emperor Meiji.
Klasik Sonrası Çağatay Türkçesi Metinlerinde Görülen p > f Değişikliği: Mensur Şâh-Nâme Örneği
Authors: TURAN Özlem , ŞEN Mesut
Published: December 2023

Kök Türkçe döneminde henüz Türk dilinde olmayan sızıcı f sesi, ilk defa Uygur Türkçesi metinlerinde, aslen f’li olan ödünç sözcüklerin yanı sıra p > f değişikliğine uğramış bazı Türkçe sözcüklerde karşımıza çıkmaktadır. Din değişikliği ile birlikte Uygur alfabesinin yanında Arap alfabesini de kullanmaya başlayan Türkler, Hakaniye Türkçesinden itibaren, içinde f sesi geçen ödünç sözcüklerin yazımında bu sesi bolca kullanmışlardır. Uygur Türkçesinde ve Hakaniye Türkçesinde f karakteri ile yazılan ödünç sözcükler, Codex Cumanicus’ta da Latin harfleri ile yine f biçiminde yazılmışlardır. Klasik Çağatay Türkçesinde Ali Şir Nevâî’nin eserlerinden itibaren bazı Türkçe sözcüklerde az sayıda da olsa p > f değişikline rastlanmaktadır. Klasik Sonrası Çağatay Türkçesi döneminde, bilhassa Doğu Türkistan bölgesinde yazılan metinlerde ise p > f değişikliğine uğramış sözcüklerin sayısı oldukça artmıştır. Bu makalede, Fransa Millî Kütüphanesi (Bibliothèque nationale de France) “SUPPL. TURC. 1010” numarada kayıtlı olan Şâh-nâme adlı el yazması eserden hareketle, p ve özellikle f sesinin Kök Türkçeden Çağatay Türkçesine kadar uzanan süreçteki durumu, Türk dilinde, patlayıcı bir ses olan p’den, sızıcı bir ses olan f’ye geçiş eğilimi incelenmiş ve Klasik Sonrası Dönem’de Doğu Türkistan bölgesinde yazılan Çağatay Türkçesinin Kumul ağzına dayandığı fikri ileri sürülmüştür.
Faktor yang Memengaruhi Customer Satisfaction dan Brand Image terhadap Customer Loyalty di Don Bakeshop Mall Grand Indonesia
Authors: Yulius Kevin Gustian
Published: December 2023

Industri jasa penyediaan makanan dan minuman di Indonesia terdiri dari berbagai jenis sektor, yang dimana terdapat industri bakery.  Jenis sektor industry ini adalah jenis industry yang memiliki keunikan karena memiliki ciri khas terhadap citra rasa dan karakteristik bisnis yang berbeda-beda. Bahkan, sektor industry bakery saat ini sudah dapat ditemukan di berbagai titik pasar baik di perkotaan ataupun di daerah. Don Bakeshop adalah salah satu bakery yang terletak pada salah satu pusat perbelanjaan terbesar di Jakarta yaitu Mall Grand Indonesia. Bakery ini sudah berkembang dan memiliki beberapa cabang di Jakarta, Don Bakeshop menyajikan berbagai macam menu seperti croissant, eclair, choux, roti, donat, kue, kopi, dan teh. Tujuan penelitian ini adalah untuk mengetahui pengaruh customer satisfaction dan brand image terhadap customer loyalty pada Don Bakeshop Mall Grand Indonesia Jakarta Pusat. Penelitian ini dimulai dari pengembangan dasar teoritis, penyebaran kuesioner, dan pengolahan data serta analisis hasil data. Penelitian ini berhasil menerima 195 responden yang berdomisili di Jabodetabek, Bedasarkan hasil penelitian yang telah dilakukan terhadap 195 responden, ditemukan bahwa customer satisfaction memiliki hubungan yang positif dan signifikan terhadap loyalitas pelanggan untuk mengunjungi Kembali Don Bakeshop. Hasil perolehan hipotesis brand image juga menunjukan adanya korelasi atau hubungan yang positif dan signifikan terhadap customer loyalty Don Bakery.
Analysis of Marta Christina Tiahahu Literacy Park as a New Tourism Object in Jakarta
Authors: Wardhani Hilda Sari , Farrah Farrah
Published: December 2023

This research discusses the readiness of Christina Martha Tiahahu's literacy park as a new tourist attraction in Jakarta. Public spaces in this capital city have an aesthetic architectural design, so they can be used as Instagramable photo spots and are expected to become new tourist attractions in urban areas. However, to become a tourist destination, the facilities that are owned still need to be studied to see whether this park is ready to become a new tourist object or needs additional equipment so that it is expected to increase the attractiveness of visitors. This research was designed with a descriptive method, namely research that leads to the disclosure of existing facts. Data collection was in the form of a literature review and direct observation to see the facilities and infrastructure owned by Blok M Literacy Park. Looking at its development and field facts the Martha Christina Tiahahu Literacy Park is currently not just a park, but its function as a tourist destination that has recreational functions, educational functions, the interaction function. As an indicator of tourism development, the level of facilities and infrastructure of the Martha Christina Tiahahu Literacy Park as a new tourist attraction has reached 80%, which includes, objects, access, accommodation, facilities, transportation, catering services, recreational activities, communication, shopping, security, cleanliness, religious facilities, and sports facilities. What is not yet available is the banking system and educational facilities. However, from this readiness, this Literacy Park is capable enough to become a new tourist destination for the community.
Batu Cermin Cave Labuan Bajo Development Strategy Based on Tourist Satisfaction Level
Authors: Rudiyanto Roseven , Iramadani Bonifasia
Published: December 2023

Tourist satisfaction is essential for the sustainability of tourism activities at tourist attractions. Batu Cermin Cave is one of the attractions in Labuan Bajo. Batu Cermin Cave underwent renovations in 2021 and reopened in 2022. Since then, no studies have shown tourist satisfaction with the services and facilities at Batu Cermin Cave. Therefore, this research aims to determine the satisfaction level and develop strategies based on the level of tourist satisfaction. This research uses a mixed-method approach with an explanatory sequential design. Quantitative data collection uses accidental random sampling techniques with survey questionnaires and qualitative data uses observation techniques. The data collected came from 124 respondents. Data was analyzed using importance-performance analysis. In the Keep Good Work Quadrant, there were nine attributes: the appearance of the tour guide, speed of service of the tour guide or staff in serving visitors, the readiness of the tour guide or staff in serving visitors, timeliness of service, reliability in service, politeness and friendliness, patience in serving, area parking, and walking paths in the Batu Cermin Cave Area. In the Low Priority Quadrant, there are four attributes: work equipment for staff and tour guides in serving visitors, trash cans, information boards, and places to eat and drink. The Overkill Quadrant is an attribute of providing exceptional services for tourists and the road to Batu Cermin Cave. In the Top Priority quadrant, namely, security when visiting Batu Cermin, toilets, and road signs to Batu Cermin Cave. The priority development strategy is based on the attributes of the Top Priority quadrant are 1) increasing visitors' sense of security when carrying out tourism activities at Batu Cermin Cave, and 2) Improving the quality of supporting facilities such as toilets and road signs to Batu Cermin Cave..
The Identifikasi Delineasi Oli Berdasarkan Nilai Resistivitas Menggunakan Metode Geolistrik Di Area “X” Tana Tidung, Kalimantan Utara
Authors: Wibowo Nobella Hadi , Djayus Djayus , Supriyanto Supriyanto
Published: December 2023

Waste pollution is a problem that must be addressed immediately. Apart from affecting the air and waters, sewage pollution can also seep below the ground surface. One of the causes of waste pollution in area "X" is the leakage of the oil storage tank by the PLTD (Diesel Power Plant) operational system in that area. This leak causes oil droplets to be absorbed into the pores of the soil and into the subsurface where it settles. To find out whether remnants of oil seepage remained in area "X" a study was conducted using the resistivity geoelectric method. The research was carried out in 2 ways, namely processing in 2 and 3 dimensions and using coring samples as a comparison of resistivity values. There were 6 coring sampling points (interval variation of 7 parts of depth) used in the study, namely coring A, B, C, D, E and F. From the six samples, an average resistivity value of 2.637 Ωm is obtained at a depth of 0-30 cm . Furthermore, at a depth of 100-130 cm it has an average resistivity value of 2.702 Ωm, at a depth of 200-230 cm it has an average resistivity value of 3.510 Ωm, at a depth of 300-330 cm it has an average resistivity value of 1.862, at a depth of 400- 430 cm has an average resistivity value of 1.928 Ωm, at a depth of 500-530 cm has an average resistivity value of 1.610 Ωm and at a depth of 600-630 cm has an average resistivity value of 1.637 Ωm. The results of this study indicate that soil contaminated with waste oil has a lower resistivity, which is in the range of 2.30 Ωm to 3.76 Ωm.
A Study of Rayleigh Waves for Predicting Soil Carrying Capacity Using the Seismik Multi-Channel Analysis Of Surface Wave (MASW) Method
Authors: Laila Nor , Munir Rahmiati , Lepong Piter
Published: December 2023

This research was conducted to determine subsurface lithology and soil carrying capacity in the study area by using the results of shear wave analysis using the MASW seismik method. This study used secondary seismic refraction data with three lines, where the data was collected on street Poros Samarinda-Tenggarong, East Kalimantan. Data processing is divided into two stages, namely the determination of the dispersion and inversion curves to produce shear wave velocity values. The resulting shear wave value is used to analyze the soil bearing capacity. The results of this study are that there is sandstone material (unsaturated) in the first layer and clay rock and at that location has a soil permit carrying capacity value range of 74.46-79.8 KPa with a moderate soil type class.
Flood Impact Assessment in Koton Karfe Using Sentinel-1 Synthetic Aperture Radar (SAR) Data
Authors: Isiaka Ibrahim Opeyemi , Ajadi Sodiq Abayomi , Arowolo Sodiq Ayobami , Mustapha Suebat Oluwakemi , Odinakachukwu Ndukwe Kingsley , Oluoma Christian Chibuike
Published: December 2023

Flood has proven to be an incessant menace in Nigeria more threatening to riverine areas. The most recent flood ensued in 2022 as a result of heavy rainfall and the release of water from Lagdo Dam in Cameroon which became very devastating in many areas notably the Koton Karfe area in Kogi State, causing business shutdowns and the loss of lives and properties. In this work, Sentinel-1 Synthetic Aperture Radar (SAR) imagery was used for flood inundation mapping, and the accompanying damages were investigated using Landsat derived Land cover maps of Koton Karfe during the 2022 devastating flood. Overall, the results obtained in this study show that the regions that felt the impact of the flood the most were the southern and western areas, which must have experienced such an impact due to their proximity to the rivers Niger and Benue and also the water coming from the upper stream part of Cameroon. Further findings revealed that during the flood period on October 13, 2022, the total inundated area in Koton Karfe was estimated to be 198.255 sq. km. In terms of damage assessment, the urban areas had reduced from 220.902 sq. km in May 2022 to 87.473 sq. km in November 2022. This shows that over 133 sq. km of the urban settlement have been lost, indicating that lives must have been lost, properties too, and humans must have been displaced. This research will assist in the space of flood emergency response and disaster management.
Planetare Gesundheit – Ein holistisches Gesundheitskonzept inmitten multipler planetarer Krisen
Authors: Schmid Jörg C. , Schwienhorst-Stich Eva-Maria
Published: December 2023

Die Überschreitung der planetaren Belastungsgrenzen mit Klimawandel und Biodiversitätszerstörung stellt eine existenzielle Bedrohung für die menschliche Gesundheit und Lebensgrundlagen dar. Das Konzept der Planetaren Gesundheit bietet ein ganzheitliches Verständnis der komplexen Zusammenhänge von Gesundheit und der Vitalität planetarer Systeme an. Um den Auswirkungen der globalen Umweltveränderungen auf die Menschen zu begegnen, ist eine Erweiterung des medizinischen Ethos und ärztlichen Handelns im Anthropozän nötig.
Ecología de una taxocenosis de Calliphoridae del área platense (Provincia de Buenos Aires) (Insecta, Diptera)
Authors: Mariluis Juan C. , Schnack Juan A.
Published: December 2023

This paper constitutes the first approach to the knowledge of the ecology of Calliphoridae from Argentina. The selected stüdied area is a rural one located at 34°55’S and 58° W in the suburbs of Villa Elisa, Province of Buenos Aires. Samples were taken hourly from 10.15 am to 4.15 pm, every month from November 1985 to October 1986. Specimens were captured with entomological net while lying on the bait composed by cow meat. The sampling program included shaded and unshaded sites. Air temperature was recorded every hour. Results showed a remarkable heliophily for some of the recorded species. Chrysomya albiceps, Phaenicia sericata, Phaenicia purpurescens and Cochlipmyia macellaria were codominants during spring and summer, while Calliphora vicina and Calliphora nigribasis were so along the winter months. Chrysomya megacephala, Cochliomyia hominivorax,. Compsomyiops fulvierura, Paralucilia fulvinota, Phaenicia eximia, and Sarconesia chlorogaster were poorly represented for most o f the sampling dates. Sex ratio was female biased for the majority of the studied species.
Dinámica de la excreción fitoplanctónica de materia orgánica (Laguna de Chascomús, Prov. de Buenos Aires, Argentina)
Authors: Romero M. Cristina , Arenas Patricia M. , Mariazzi Aldo A.
Published: December 2023

The rate of phytoplankton excretion of organic matter was measured by acidification of water samples incubated in the laboratory following the Steemann Nielscn method (1952). After the release of inorganic 14C,14C-organic carbón was estimated through Berman's methodology (1976).

Percentages of excretion of organic carbón ranged bctween 8 and 18% (mean value 13,5%) were the lowest observed, supporting the hypothesis that the cxcretion is lower in eutrophic waters. Thesc percentages incrcascd during winter and decresed during summer: instead rates of release of organic matter showed a bimodal distribution with two máximum valúes, one in winter and other in summer (57,6 and 72,0 mg C • m-3 • h-1, respectively). Percentages of cxcretion showed and inverse relationship with phytoplankton photosynthesis and chlorophyll-a concentrations (P < 0,01). Scasonal fluctuations of excretion were influenced by light intcnsity, with higher light rates during winter than in summer.
Cuantificación, frecuencia de división celular y producción de bacterias planctónicas en el Embalse del Río III - variables relacionadas
Authors: Di Siervi Miguel A. , Mariazzi Aldo A. , Donadelli Jorge L.
Published: December 2023

During a whole year (1987-1988), monthly variations of biomass, frequency of dividing cells and production of bacterioplankton were studied in the Embalse del Río III Reservoir (Córdoba, Argentina). Algal biomass and production were measuredsimultaneously. A significant relationship between bacterial and algal production was observed, being temperature an important regulator factor. Bacterial biomass valúes did not correlate with their production rates. Low valúes and variability in the frequency of dividing cells were probably due to methodological difficulties for detecting división in very little cells. These data suggest that the frequency of dividing cells is not a reliableindicator of total active bacteria. Annually bacteria cycled nearly 60% of organic matter produced by phytoplankton in the water column.
La fauna bentónica y su relación con la contaminación orgánica en el Río Negro, Prov. Chaco (Argentina) Estudio Preliminar
Authors: Varela María E. , Di Persia Danilo H. , Bonetto Argentino A.
Published: December 2023

The Negro River (Chaco Province), an affluent of the Paraná River, receives the effluents coming from the several industries established along its margíns. As a result, its lower strech is variably affected by processes of organic polution, determining astrong change in the limnological conditions, particulary conceming to the dissolved oxygen, which becomes almost exhausted in areas of considerable extention. In consequence, the general conditions for the animal life are severe, and only those species with special adaptations can survive.

This paper develops the general study of the benthic fauna, with special reference to the differente species of oligochaetes and their populations, in relation to the processes of polution. Several aspects referred to the valué of oligochaetes as biological indicators of the water quality are also discussed.
Estructura y dinámica de población de Tigriopus californicus (Copé´´poda, harpacticoida)
Authors: Lombardo Rubén J. , Pallares Rosa E.
Published: December 2023

From January 1976 to July 1979, samples of a population of the copepod Tigrlopus californicus were collected at monthly intervals on lower supralittoral level tide pools at Península Foca, ría Deseado (Santa Cruz).

Density and samples composition in males, ovigerous and nonovigerous females, coupled individuals and juveniles were determined. Females usually were significantly more abundant than males. The seasonal density changes are considered with respect to the physical environment. Copepods were present throughout the year but abundance in summer is several orders of magnitude greater than in winter, through a rapid autumn decline. A large density increase in spring complete the annual cycle. The frequency of this maxima and mínima appeared to be periodic in time during the sampling years, in annualy cycles. Natural mortality and instantaneous rates of population increase were estimated,and the last compared with the species reproductive potential (computed "in vitro", previously published). The periodic density fluctuation is considered with respect to the seasonal changes in poblational structure through cyclical modifications of the instantaneous rates of population increase.
Effects of Radiotherapy and Chemotherapy on Platelet in Patients with Lung Cancer
Authors: Tang Shanshan , Li Li , Yuan Shuanghu
Published: December 2023

Background: An animal study has shown that platelets form are formed in the lungs. Therefore, we wanted to study the relationship between lung radiation dose and platelet count in lung cancer patients receiving radiation therapy. Methods: This retrospective study included 93 patients with lung cancer who received radical thoracic radiation therapy. The correlation between pulmonary dose-volume histogram (DVH) parameters and thrombocytopenia during radiotherapy (RT) was evaluated by chi-square test, logistic regression analysis, Spearman and Pearson correlation analysis, etc. Results: Thrombocytopenia occurred in 17 of 93 patients (18.3%). Chi-square test and logistic regression analysis showed that chemotherapy (p = 0.038), MLD (mean lung dose, p = 0.001), V5 (p = 0.008), V10 (p = 0.004), AND V20 (p = 0.003) were important independent predictors of thrombocytopenia. Using the chi-square test, increased MLD (p = 0.002), V5 (p = 0.021), V10 (p = 0.008), and V20 (p = 0.006) were associated with increased risk of thrombocytopenia. Receiver operating characteristic (ROC) curve was used to analyze the thresholds of MLD, V5, V10, and V20, which showed high sensitivity and specificity for distinguishing between non-thrombocytopenia and thrombocytopenia. Conclusions: Higher doses of radiation to the lung are associated with an increased risk of thrombocytopenia. Moreover, optimization of treatment plans via the control of DVH parameters may reduce treatment interruptions and improve outcomes in lung cancer patients treated with RT.
Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway
Authors: Zhu Qing , Han Yuanshan , He Ying , Fu Yilan , Yang Hui , Chen Yun , Shi Yingrui
Published: December 2023

Background: Breast cancer-related depression (BCRD) is strongly associated with BC and increases recurrence and mortality. This study investigated the role of kaempferol in the pathogenesis of BCRD and its underlying mechanism. Methods: 4T1 mouse BC cells were treated with corticosterone (Cort) in vitro to develop a neuronal injury model, and a BCRD mouse model was established by injecting 4T1 cells and Cort. The effects of kaempferol on 4T1 cells and BCRD models were measured by behavioral tests, Cell Counting Kit-8 assay, wound healing assay, colony formation assay, Western blot analysis, quantitative real-time PCR, hematoxylin and eosin staining, enzyme-linked immunosorbent assay, and immunofluorescence. BCRD cells were transfected with the cyclo-oxygenase-2 (COX-2) overexpression plasmid to study the role of the COX-2/prostaglandin E2 (PGE2) axis in the anti-BCRD activity of kaempferol. The connection between kaempferol and COX-2 was analyzed by molecular docking. Results: Kaempferol reduced the viability, migration, and clones of 4T1 cells and inhibited BC growth and depression-like behavior in mice. Kaempferol alleviated inflammation in BCRD, decreased interleukin 1 beta (IL-1β) and IL-6 levels, and increased transforming growth factor beta 1 (TGF-β1) and IL-10 levels. In addition, kaempferol elevated the levels of serotonin, dopamine, and norepinephrine and the amount of 5-Bromo-2′-deoxyuridine/neuronal nuclei-positive cells. Kaempferol downregulated COX-2 and PGE2, and kaempferol could dock with the protein structure of COX-2. Overexpression of COX-2 reduced BCRD viability, upregulated IL-1β and IL-6 levels, and downregulated TGF-β1 and IL-10 expression. Overexpression of COX-2 reversed the protective effects of kaempferol. Conclusion: Kaempferol exerted anti-BCRD effects, at least in part by inhibiting the COX-2/PGE2 pathway, which regulates neuroinflammation, neurotransmitter imbalance, and defective neurogenesis. Therefore, kaempferol may be a promising candidate active ingredient for treating BCRD.
Unveiling Circular RNA-Mediated Regulatory Mechanisms in Necroptosis in Premature Ovarian Failure
Authors: Jin Xin , Chen Wenjun , Wang Jiaxi , Xu Xianli , Zhang Ting , Wang Lu , Feng Xuehua
Published: December 2023

Background: Necroptosis is a programmed necrotic cell death, in which dying cells rupture and release intracellular components that trigger a proinflammatory response. The current study aimed at probing the circular RNA (circRNA)-mediated regulatory mechanisms in necroptosis in premature ovarian failure (POF). Methods: CircRNA sequencing analysis was conducted in ovarian tissues of control and POF rats and transcriptome microarrays were acquired from the GSE33423 dataset. Differential expression analysis of circRNAs and mRNAs was executed between the POF and control data. Both a necroptosis-based circRNA–microRNA (miRNA)–mRNA network and a protein–protein interaction (PPI) network were established. Then, the functional annotation and immunological traits were analyzed. Results: Totally, 1266 upregulated and 1283 downregulated circRNAs as well as 1101 upregulated and 1168 downregulated mRNAs were determined in the POF rats versus the controls. The differentially expressed mRNAs predominantly correlated with necroptosis. The circRNA–miRNA–mRNA networks of downregulated necroptosis genes (comprising rno_circRNA_004995-rno-miR-148b-5p-H2afy2, rno_circRNA_016998-rno-miR-29a-5p-Hmgb1, and rno_circRNA_017593-rno-miR-29a-5p-Hmgb1) and upregulated necroptosis genes (comprising rno_circRNA_015900-rno-miR-935-Stat1, rno_circRNA_007946-rno-miR-328a-3p-Stat5a, rno_circRNA_007947-rno-miR-328a-3p-Stat5a, rno_circRNA_005064-rno-miR-18a-5p-Stat1, rno_circRNA_005064-rno-miR-18a-5p-Stat5a, rno_circRNA_005115-rno-miR-22-3p-Stat1, rno_circRNA_009028-rno-miR-342-5p-Stat1, rno_circRNA_011240-rno-miR-1224-Stat5a, rno_circRNA_016078-rno-miR-711-Stat5a) were built. POF-specific necroptosis genes (STAT1, STAT5A, PLA2G4A, HMG1L1, HMGB1, AGER, EGFR, HDAC7, IFNA1, IL10RB, IL27RA, PYGL, SOCS1, TRADD, CXCL10, DDX5, EZH2, FADS2, FER, H2AFY2, HIST1H2AF, IFI44L, IL27, IRGM, MX1, NFKB2, PAFAH2, PEMT, PGM2L1, PGR, PHKA2, and PLB1) were selected since they displayed notable associations with most immune cells, immune checkpoints, chemokines, human leukocyte antigen (HLA) molecules, and immune receptors. Conclusions: Altogether, we proposed the presence of widespread regulatory mechanisms of circRNAs in necroptosis and demonstrated that altered circRNA biogenesis might contribute to POF by affecting necroptosis.
Aspirin Inhibits Brain Metastasis of Lung Cancer via Upregulation of Tight Junction Protein Expression in Microvascular Endothelial Cells
Authors: Wei Dianfang , Tang Ming , Gong Weibo , Liu Jingshuo , Qin Lijuan
Published: December 2023

Background: The brain is one of the most vulnerable metastasis sites in lung cancer; approximately 40–50% of lung cancer patients develop brain metastasis during the disease course, contributing to the poor prognosis and high mortality of lung cancer patients. Therefore, it is important to clarify the molecular mechanism underlying brain metastasis of lung cancer for improving the overall survival of lung cancer patients. The present study aimed to investigate the potential role of blood-brain barrier (BBB) permeability in the development of brain metastasis of lung cancer and explore the effect of aspirin in an in-vitro BBB model. Methods: An in-vitro BBB model was established. The expression of heat shock protein 70 (HSP 70), zonula occludens-1 (ZO-1), and occludin in rat brain microvascular endothelial cells was detected using Western blot at different time points following the administration of aspirin. Results: HSP70, ZO-1, and occludin expressions did not show significant changes before aspirin administration, but increased noticeably after aspirin administration. Tumor necrosis factor-α (TNF-α) could significantly attenuate the increased expression of these proteins induced by aspirin. Additionally, TNF-α also significantly reversed the aspirin-induced decrease of BBB permeability. Conclusions: Aspirin may inhibit brain metastasis of lung cancer in a time-dependent manner via upregulating tight junction proteins to reduce BBB permeability, and this effect can be reversed by TNF-α.
ProSE-Pero: Peroxisomal Protein Localization Identification Model Based on Self-Supervised Multi-Task Language Pre-Training Model
Authors: Sui Jianan , Chen Jiazi , Chen Yuehui , Iwamori Naoki , Sun Jin
Published: December 2023

Background: Peroxisomes are membrane-bound organelles that contain one or more types of oxidative enzymes. Aberrant localization of peroxisomal proteins can contribute to the development of various diseases. To more accurately identify and locate peroxisomal proteins, we developed the ProSE-Pero model. Methods: We employed three methods based on deep representation learning models to extract the characteristics of peroxisomal proteins and compared their performance. Furthermore, we used the SVMSMOTE balanced dataset, SHAP interpretation model, variance analysis (ANOVA), and light gradient boosting machine (LightGBM) to select and compare the extracted features. We also constructed several traditional machine learning methods and four deep learning models to train and test our model on a dataset of 160 peroxisomal proteins using tenfold cross-validation. Results: Our proposed ProSE-Pero model achieves high performance with a specificity (Sp) of 93.37%, a sensitivity (Sn) of 82.41%, an accuracy (Acc) of 95.77%, a Matthews correlation coefficient (MCC) of 0.8241, an F1 score of 0.8996, and an area under the curve (AUC) of 0.9818. Additionally, we extended our method to identify plant vacuole proteins and achieved an accuracy of 91.90% on the independent test set, which is approximately 5% higher than the latest iPVP-DRLF model. Conclusions: Our model surpasses the existing In-Pero model in terms of peroxisomal protein localization and identification. Additionally, our study showcases the proficient performance of the pre-trained multitasking language model ProSE in extracting features from protein sequences. With its established validity and broad generalization, our model holds considerable potential for expanding its application to the localization and identification of proteins in other organelles, such as mitochondria and Golgi proteins, in future investigations.
Dexmedetomidine Alleviates Ischemia/Reperfusion-Associated Acute Kidney Injury by Enhancing Autophagic Activity via the α2-AR/AMPK/mTOR Pathway
Authors: Zhou Bi-Ying , Yang Jing , Luo Rui-Rui , Sun Yan-Lin , Zhang Hao-Tian , Yang Ai-Xiang , Zhang Guo-Xing
Published: December 2023

Background: Dexmedetomidine (DEX) reportedly protects against ischemia-reperfusion (I/R) injury and associated damage to the kidneys, but the underlying mechanisms have yet to be established. Methods: Unilateral nephrectomy was performed in Wistar rats, and the remaining kidney was clamped for 1 h prior to reperfusion to establish an experimental model system. These animals were then randomized into Sham, DEX + Sham, DEX + I/R, ATI (Altepamizole, α2-adrenergic receptor inhibitor) + DEX + I/R, and 3-MA (3-methyladenine, autophagy inhibitor) + DEX + I/R groups. Serum renal function biomarkers, acute kidney injury (AKI) histopathological scores, serum inflammatory factors, redox biomarkers, markers of autophagic flux, and autophagosome numbers were assessed. Levels of proteins related to the autophagic pathway, including mTOR and AMPK, were also analyzed. Results: Serum creatinine and urea nitrogen levels in the I/R group were significantly elevated over those in sham control rats, as were AKI scores, serum inflammatory cytokine concentrations (IL-6, IL-1β, and TNF-α), and serum levels of the oxidative stress biomarker malondialdehyde (MDA). All of these parameters were significantly reduced in the DEX + I/R group relative to I/R model rats. I/R group rats also exhibited significant decreases in renal levels of autophagic flux-related biomarkers and autophagosome numbers relative to sham controls, while DEX administration partially restored normal autophagic flux in these rats. Acute I/R also suppress the expression of AMPK in the kidney while increasing mTOR expression, and DEX reversed these effects. The beneficial impact of DEX on I/R-associated AKI was ablated by ATI or 3-MA administration. Conclusions: These analyses provide strong evidence for the ability of DEX to protect against I/R-associated AKI via the α2-AR/AMPK/mTOR pathway-mediated enhancement of autophagic activity.
Evolution and limiting factors of the US strategy in Central Asia
Authors: Xiaochen Shen
Published: December 2023

The essence of the development of five successive US strategies for the Central Asia during the past 30 years was the evolution of America's strategic perception, instead of its absolute strategic capability in this area. Meanwhile, the efficiency of its strategic implementation has been affected by two dimensions of uncertainty that of the future of the regional integration and Afghanistan problem.