bluuebunny/crossref_metadata_2025 huggingface dataset:
ESTIMASI NILAI RIPITABILITAS BOBOT SAPIH DAN MOST PROBABLE PRODUCING ABILITY KAMBING SABURAI BETINA DI KECAMATAN SUMBEREJO, GISTING, DAN KOTA AGUNG TIMUR KABUPATEN TANGGAMUS
Authors: Saputra Ibrahim Ikhlas , Sulastri Sulastri , Hamdani Muhammad Dima Iqbal , Dakhlan Akhmad
Published: April 2021

The research was conducted with the aim of knowing the repeatability estimate and Most Probable Producing Ability (MPPA) value of the weaning weight of female Saburai goats. This research was conducted from July to September 2019 in Gisting, Sumberejo, and East Kota Agung districts, Tanggamus regency, which is the development area for Saburai goat seeds. This research used a survey method. The data used was in the form of primary data obtained from breeders through questionnaires and secondary data, namely in the form of farmer's goat records. The research material consisted of recording of female Saburai goats which had given birth more than twice. The records required in this study included age of dam at delivery, age of kid at weaning (weaning age), kid's birth weight, weaning weight of the kid, type of birth, and sex from 2016 to 2018, and questionnaires for breeders. The results of this study indicated that repeatability estimate of weaning weight of Saburai goat in Gisting, Sumberejo, and East Kota Agung districts were 0.478 (high category), 0.19 (low category) and 0.13 (low category), respectively. The results also indicated that the average MPPA value of weaning weight for Saburai goats in Gisting, Sumberejo, and East Kota Agung districts were 21.91 � 0.04, 17.91 � 0.06, and 9.88 � 0.01, respectively.

Keywords: Most probable producing ability, Repeatability estimate, Saburai goat
PERBANDINGAN PERFORMA PERTUMBUHAN PADA SAPI PERANAKAN ONGOLE DI DESA PURWODADI DALAM DAN DESA WAWASAN, KECAMATAN TANJUNGSARI, KABUPATEN LAMPUNG SELATAN
Authors: Kurniawan Ega , Husni Ali , Sulastri Sulastri , Adhianto Kusuma
Published: April 2021

This research aimed to compare the growth performance of Ongole Grade (PO) cattle in Purwodadi Dalam and Wawasan villages. This research was conducted from December 2019 to January 2020 at the People's Animal Husbandry Center, Wawasan Village and Purwodadi Dalam Village, Tanjungsari District, South Lampung Regency, Lampung Province. This study used a survey method (purposive sampling), using primary and secondary data. The observed variables were birth weight, weaning weight and yearling weight. The results showed that the average weight gain of PO cattle in the village of Wawasan was 84.33 � 19.18 kg / head, which was higher than that of Purwodadi Dalam, namely 80.17 � 19.49 kg / head. The body weight gain after weaning of PO cattle in Wawasan Village was 39.15 � 21.34 kg, higher than that in Purwodadi Dalam Village, namely 37.75 � 21.10 kg / head. The body weight gain from birth to one year of PO cattle in Wawasan Village was 123.49 � 26.26 kg / head, which was also higher than that in Purwodadi Dalam Village, namely 117.93 � 30.50 kg / head. The results also showed that the corrected weaning weight of PO cattle in Wawasan Village (122.40 � 23.20 kg / head) was higher than that in Purwodadi Dalam Village (121.24 � 22.86 kg / head), and the average body weight of one year old of PO cattle in Wawasan Village was 147.95 � 26.58 kg / head higher than that in Purwodadi Dalam Village with an average weight of 141.98 � 31.37 kg / head. The results of the current study concluded that the growth performance of PO cattle in Wawasan Village was better than those in Purwodadi Dalam Village. Keywords: Growth performance, Ongole Grade (PO) cattle, Weaning weight, Yearling weight
PENGARUH MANIPULASI IKLIM KANDANG MELALUI PENGKABUTAN TERHADAP RESPON FISIOLOGIS DAN KETAHANAN PANAS KAMBING SAPERA DAN PERANAKAN ETTAWA
Authors: Setiawan Arif Adham , Erwanto Erwanto , Hartono Madi , Qisthon Arif
Published: April 2021

This study aimed to determine the effect of cage microclimate manipulation with misting on physiological responses and heat resistance of goats (Sapera and Ettawa Grade). This research was conducted in April - May 2020 at Telaga Rizki People's Farm, Metro City, Lampung Province. This study used an experimental method, Split Plot design with a completely randomized design (CRD). This study used two treatments, namely modification of the pen consisting of pens without misting (K0) and pens with misting (K1) and two breed of goats, namely Sapera and Ettawa Grade (PE) goats. Each treatment was carried out 3 times. Goats as subplots and microclimate modification of the pen as the main plot. In this study, twelve female goats were used, namely 6 Sapera goats and 6 Ettawa Grade (PE) goats aged 2-3 years. The parameters observed were microclimate condition, namely air temperature, relative humidity (RH), and Temperature Humidity Index (THI), and physiological responses including rectal temperature, respiration frequency, heart rate frequency, and heat tolerance (HTC). The results of the research showed that there was significant effect (P<0.05) of treatments on RH and THI. The resilts also showed that there was no significant effect (P>0.05) of treatments on rectal temperature, heart rate, respiration frequency, HTC and environment temperature.

Keywords : Misting, Pens microclimate, Physiological responses
Evaluating Trade Corridor Performance: A Myanmar Case Study
Authors: Banomyong Ruth , Fernandez Thomas E.
Published: April 2021

The purpose of this paper is to assess the logistics performance of national trade corridors in Myanmar based on a theoretical portrayal of multimodal transport in logistics chains combined with the real-time operation of such chains. A cost-time-distance model was used as the core theoretical framework for the discussion. Empirical data related to cost, time and distance was obtained to evaluate national trade corridors in Myanmar. The study explored the performance of trade corridor in the pulses and beans sector from the largest sown and harvest areas to the main seaports in Myanmar. The pulses and beans sector was selected because the country is the 2nd highest exporter in the world and would benefit from improved access to its national seaports. Under the cost-time-distance model used, it was observed that physical infrastructure, institutional environment as well as limited capability of local providers hindered the overall performance of the trade corridors under study.
Prevalence of pathological lesions diagnosed by cytology in cats, with association of diagnosis to age, breed and gender
Authors:   Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia, Huber Doroteja , Ristevski Tonka , Gudan Kurilj Andrea , Maurić Maja , Medven Zagradišnik Lidija , Hohšteter Marko , Šoštarić-Zuckermann Ivan-Conrado
Published: April 2021

Cytology is the diagnostic procedure of the microscopic evaluation of cells. It is becoming increasingly important and more frequently used in veterinary diagnostics, having many advantages including simplicity, speed and low cost. To determine the pathological changes diagnosed by cytology in cats, as well as the distribution of age, breed and gender in the diagnosed changes, we performed a retrospective study on slides submitted to the Department of Veterinary Pathology for routine cytological examination. The archive was searched for all feline cytology slides submitted from 2009 to 2018. All the slides were re-evaluated and classified into one of the four pathological processes: ‘neoplasia’, ‘inflammation’, ‘other condition’ or ‘non-diagnostic sample’. Breed, age, gender and the tissue from which the lesion was sampled were noted from the submission form, and statistically analyzed. The most frequent type of pathological process diagnosed was neoplasia, which reflects the high prevalence of neoplastic diseases in cats reported in literature data. Pathological changes were mostly diagnosed in domestic shorthaired cats of both sexes, with an average age of 8.4 years, but no breed, age or gender predisposition was found. The most evaluated tissue was skin, probably due to its accessibility and the ease of obtaining a sample from skin lesions. The most frequent neoplasia were malignant and the most frequent diagnosis was round cell neoplasia. Cats affected with round cell neoplasia had a significantly lower average age (7.3 years) than cats diagnosed with epithelial and mesenchymal neoplasia (9.9 and 10.3 years, respectively), probably reflecting the common retroviral infection in Croatian cats.
The influence of clinical and chronic forms of magnesium deficiency on the haematological parameters of dairy cows
Authors:   Department and Clinic of Animal Internal Diseases, Faculty of Veterinary Medicine. University of Life Sciences, Lublin, Poland, Abramowicz Beata , Lutnicki Krzysztof , Kurek Łukasz
Published: April 2021

The aim of the study was to determine the influence of hypomagnesaemia on the haematological status and predictive values of haematological tests in the diagnosis of magnesium (Mg) deficiency in dairy cow herds. The study was carried out on 100 dairy HF cows, divided into two experimental groups and a control one.The two experimental groups (I - clinical form of hypomagnesaemia, II - chronic form of hypomagnesaemia) consisted of 40 cows and the control group consisted of 20 healthy cows. Blood samples were collected twice: before the commencement of the therapy and after three months. In both hypomagnesaemic groups, low erythrocyte count, haemoglobin (Hgb) concentration and hematocrit (Ht) index values were observed. The indirect parameters of the erythrocyte system were within the standard reference range, with the exception of the mean corpuscular hemoglobin (MCH) index, which, in approx. 45% of animals, was below the lower limit of the normal range. Haemolytic normocytic normochromic anaemia was detected through the hypomagnesaemia of the cows. In the first and second group, at the first blood sampling an increase in the eosinophil count was observed, which was statistically significant in relation to the second sampling. In the blood smear test, a variety of erythrocyte sizes (anisocytosis), polychromasia and Howell-Jolly bodies were detected in the affected cows. After supplementation with magnesium, the concentration of Mg in the serum of the treated animals returned to normal more rapidly than the haematological parameters. The authors assumed that these in the haematological parameters may be helpful in indicating the need for Mg supplementation.
The Role of Social Media on Sponsorship Activation
Authors: Barbu Mihai Constantin Răzvan , Burcea George Bogdan , Diaconescu Dragoş Laurenţiu , Popescu Marius Cătălin , Păsărin Leonardo Daniel , Apostu Paula
Published: April 2021

"ABSTRACT. Globally, sponsorship has grown impressive over the last 30 years, receiving an increased importance in the communication mix of companies. Sport organizations have understood the importance and the role sponsorship it plays for the financial support they need. Sponsorship is the material support of an event, activity or organization by an unaffiliated partner. It is a good way to increase brand awareness, which helps to generate consumer preferences and promote brand loyalty and also improves the brand image. Brands play an important role in the development of companies because they bring a number of benefits to them. The paper ""Innovation’s impact on sponsorship activation"" aims to present a series of theoretical elements of activating sponsorship, as well as the element of innovation in this process, an element represented by the social media presence in our lives and in the last part of the paper is presented a study based on a survey on our topic."
Glycemic Variation in Patients of Acute Coronary Syndrome with Hyperglycaemia and its Relationship with Oxidative Stress: A Pilot Study
Authors:   Assistant Professor, Department of Medicine, University College of Medical Sciences & G.T.B. Hospital, Delhi, India, Kumar Kuldeep
Published: April 2021

Aim:The aim of this study was to establish the relationship between the glycemic variation in patients of Acute Coronary Syndrome (ACS) with hyperglycemia, oxidative stress and pre-discharge assessment of glycemic status by Oral Glucose Tolerance Test (OGTT). Materials and Method: Nineteen non-diabetic patients who presented with acute coronary syndrome with random blood sugar ≥200 mg/dl were recruited and glycemic variation was measured using CGMS followed by measurement of 8-isoprostanes PG-2alpha as a marker of oxidative stress, and pre-discharge OGTT was done to know the glycemic status at the time of discharge. Result: Mean MAGE (A parameter of glycemic variation) was 106.92±22.66 and mean 8-isoprostanes level was 206.05±179.57. There was no relationship between these two values. On doing OGTT, out of 19 non diabetic patients 11 turned out to be frank diabetic and 8 were having impaired glucose tolerance after OGTT, none were euglycemic. Conclusion:The study highlighted the issue of hyperglycaemia in ACS patients and their abnormal glucose tolerance in the short term, most of them turning to be frankly diabetic and being totally asymptomatic till the time of index event, although no correlation was found between glycemic variability and oxidative stress.
Prevalence of Extrapulmonary Tuberculosis in Newly Registered HIV Patients
Authors:   Assistant Professor, University College of Medical Sciences & G.T.B. Hospital, Delhi, India, Kumar Kuldeep
Published: April 2021

Introduction: Human Immunodeficiency Virus infection and Tuberculosis are among the ten leading causes of death worldwide. In advanced AIDS, M. tuberculosis frequently causes disseminated Extra-Pulmonary Tuberculosis (EPTB). EPTB being paucibacillary infection poses a diagnostic challenge. The emergence of Cartridge Based Nucleic Acid Amplification Test (CBNAAT) has marked an important development in the field of rapid molecular diagnostics of tuberculosis. Aims and Objective: The purpose of this study was to determine the prevalence of EPTB in newly registered HIV patients visiting ART clinic and to find the prevalence of Rifampicin resistance using CBNAAT. Materials and Method: 213 newly registered HIV patients were included in the study recruited over 10 months time period and followed up for six months from recruitment. Case record of each patient with detailed history, clinical examination and necessary blood, radiological and specimen sampling done to investigate for tuberculosis was maintained. The data obtained were analyzed using SPSS 20.0 software. Result: The prevalence of EPTB in newly registered HIV patients was found to be 14.5%, with abdomen being the most common site for EPTB. Rifampicin resistance was seen in 3.2% cases. Conclusion: The result of this study showed that the prevalence of EPTB was higher compared to PTB in HIV patients. CBNAAT sensitivity for different samples were variable. This study showed maximum sensitivity of CBNAAT for lymph node aspirate (100%) and minimum for CSF (0%). Overall the sensitivity of CBNAAT was low, yet it is a very useful investigation for detection of EPTB with high positive predictive value.
Pandemic Dynamics, the three Waves of COVID-19 and the Way Ahead
Authors:   Professor, Community Medicine, Ruxmaniben Deepchand Gardi Medical College, Ujjain, Madhya Pradesh, India, Mishra Badrinarayan
Published: April 2021

Spread of a new pandemic in waves is a natural phenomenon. It has happened in past and also unfolding in present COVID-19 scenarios. Many players determine the outcome of the diseases during these waves of activities. This article discusses the past pandemics, lessons learnt from them and the 3 waves that have been recorded to date for SARS-CoV-2 (the novel coronavirus) and drawing parallel wherever feasible along with an element on its future course.
Epidemic Trajectory in the Absence of Non-Pharmacological Interventions in India: An Insight into Post Vaccine Introduction Phase
Authors:   Deputy Director, Department of Epidemiology Division, NCDC, Delhi, India, Dhuria Meera
Published: April 2021

Background: Non-Pharmacological Interventions (NPIs) have proven to be effective in controlling and reducing the spread of SARS-CoV-2 in the population. During the year 2020, before vaccine introduction, India has been through various phases of COVID-19 pandemic response such as nationwide lockdown phase 1 to 4 and unlock phases 1-8. Although India’s vaccination program against COVID-19 has started, it is still in the initial phases and considering the humongous population of India, coverage of entire population with vaccine needs time. Methodology: We designed a model showing the projections of expected incident cases of COVID-19 under two scenarios for the month of February 2021. In the first scenario, Rt value expected to be observed during February 2021 if all the NPIs are removed was considered. In the second scenario, Rt value projected as per the current trend with NPIs in place was considered. Model projections of both these scenarios were done for India and also for Delhi. Result: Our simulation model quantifies the effect of Non-pharmacological interventions on the current pandemic situation in India and Delhi, which concludes that relaxation in preventive measures or COVID-19 appropriate behaviors or ceasing of NPIs shall see an exponential rise in the daily incident cases. Comparing the trajectories for India and Delhi, it can be deduced that if NPIs cease to exist for one month, the daily incident cases can be many times higher of normal in India and also in Delhi by the end of February 2021. Conclusion: NPIs remain to play a major role in containing the spread and minimizing the effects of COVID-19 pandemic. Any kind of relaxation in NPIs can lead to sudden surge of incident cases and correspondingly may increase the death toll.
Evaluation of whether acepromazine maleate causes fentanyl to decrease the minimum alveolar concentration of isoflurane in cats
Authors: Brosnan Robert J. , Pypendop Bruno H.
Published: April 2021

OBJECTIVE

To determine whether isoflurane-anesthetized cats with demonstrated resistance to the immobilizing effects of fentanyl would exhibit naltrexone-reversible sparing of the minimum alveolar concentration (MAC) of isoflurane when fentanyl was coadministered with the centrally acting catecholamine receptor antagonist acepromazine.

ANIMALS

5 healthy male purpose-bred cats.

PROCEDURES

Anesthesia was induced and maintained with isoflurane in oxygen. Baseline isoflurane MAC was measured by use of a standard tail clamp stimulus and bracketing study design. Afterward, fentanyl was administered IV to achieve a plasma concentration of 100 ng/mL by means of target-controlled infusion, and isoflurane MAC was remeasured. Next, acepromazine maleate (0.1 mg/kg) was administered IV, and isoflurane MAC was remeasured. Finally, isoflurane concentration was equilibrated at 70% of the baseline MAC. Movement of cats in response to tail clamping was tested before and after IV bolus administration of naltrexone. Physiologic responses were compared among treatment conditions.

RESULTS

Isoflurane MAC did not differ significantly between baseline and fentanyl infusion (mean ± SD, 1.944 ± 0.111% and 1.982 ± 0.126%, respectively). Acepromazine with fentanyl significantly decreased isoflurane MAC to 1.002 ± 0.056% of 1 atm pressure. When isoflurane was increased to 70% of the baseline MAC, no cats moved in response to tail clamping before naltrexone administration, but all cats moved after naltrexone administration.

CONCLUSIONS AND CLINICAL RELEVANCE

Acepromazine caused fentanyl to decrease the isoflurane MAC in cats that otherwise did not exhibit altered isoflurane requirements with fentanyl alone. Results suggested that opioid-mediated increases in brain catecholamine concentrations in cats counteract the opioid MAC-sparing effect.
Cervical Fracture with Piriform Sinus Laceration
Authors: Chialda Mihaela
Published: April 2021

Particular case of complex cervical trauma by associating a cervical fracture with piriform sinus laceration. The trauma is located in the anatomo-topographic zone II. Delayed onset at 24 hours of digestive symptoms, swallowing disorders, sialorrhea, dysphagia, subcutaneous cervical emphysema. CT with Optiray contrast agent is performed, an investigation that reveals a gap in the left piriform sinus of 5-6 mm. The evolution is favourable under conservative treatment, nasogastric tube, broad spectrum antibiotic treatment.
Intramuscular Abdominal Wall Endometriosis, an Unusual Finding for General Surgeon
Authors: Miheţiu Alin , Bratu Dan , Popescu Oana
Published: April 2021

Defined as the ectopic development of uterine tissue outside the uterine cavity, endometriosis is an increasingly common condition that can lead to various complications from chronic pain syndrome, infertility, obstruction due extrinsic compression to malignancy of endometriosis foci. Extrapelvic positioning of endometriosis is rare, diagnosis can be difficult both clinically and imaging, and treatment does not always ensure the absence of recurrences.
The Technology of Obtaining Flexible Dentures in Dental Practice, Theoretical and Practical Aspects
Authors: Malița Mădălina Adriana , Ionescu Camelia , Perieanu Viorel Ștefan , Burlibașa Mihai , Dina Magdalena Natalia , Costea Radu , Perieanu Mădălina Violeta , Costea Raluca , Babiuc Iuliana , Beuran Irina Adriana , Tănase Gabriela , Chirilă Mihaela , David Mihai , Voinescu Ioana , Moraru Liliana
Published: April 2021

Flexible dentures are an increasingly interesting prosthetic alternative both for dental practitioners (dentists and dental technicians), but also for patients. This type of prosthetic restoration can rehabilitate a wide range of edentulous, but the financial effort that patients have to make is more consistent than in the case of a partial acrylic dentures. In this study, we will try to present some essential aspects in the technology of creating flexible partial dentures.
Behavioural Etiological Factors that Contribute to the Occurrence of Severe Early Childhood Caries
Authors: Eşian Daniela , Bica Cristina , Bud Anamaria , Stoica Oana , Bud Eugen
Published: April 2021

Severe early childhood caries (S-ECC) is one of the most common pathologies affecting primary dentition. The complex etiology is the result of the interaction of microbial factors and also of dietary factors. For this study a group of 40 children diagnosed with S-ECC was compared with a control group of 35 children without caries. The study data was obtained through clinical examination of both children and mothers, and on the basis of a questionnaire completed by the mothers of the subjects. The odontal status of the mothers was evaluated by determining the DMFT index. The results of the study showed that the mothers of the subjects with S-ECC had a significantly higher DMF-T caries index than the ones in the control group and that there is a close link between the birth of the child, newborn feeding method, mother’s habits, cariogenic diet and the occurrence of severe early childhood caries.
Diagnosis and Treatment of Patients with Traumatic Retroperitoneal Hematoma Complicated with Bone Fractures
Authors: Daniel Filip , Vasile Sarbu
Published: April 2021

Objective: Traumatic retroperitoneal hematoma (RPH) is an underdiagnosed entity, turned to have a high mortality rate, when is not earlier diagnosed. Our aim was to analyze our experiences in patients with traumatic RPH complicated with bone fractures, and highlight the problems in diagnosis and treatment to facilitate the surgeon’s decision.

Methods: In this retrospective study, all cases who presented to the emergency room (ER) and/or admitted to our center with bone fractures complicated with RPH from January 2016 to December 2019 were included (4-years data). Data collected included age, hematoma zones, fracture production mechanisms, mortality, surgical intervention, bones lesions frequency, frequency of pelvic bone injuries, complications and biochemical and hematological analysis (e.g. hemoglobin (Hb), hematocrit (Ht), platelets (PLT), leukocytes (Leu), aspartate aminotransferase level (AST), alanine aminotransferase level (ALT) and creatinine (Cr). All RPHs were diagnosed using computed tomography scan.

Results: A total number of 173 RPH cases with bone fractures were included with a mean age of 48.80±1.40. Zone II and III (lateral and pelvic hematoma) bleed were the most common type of RPH. The main fracture production mechanism was road accident (n=110). The bone lesions frequency besides pelvis, was seen in lumbar vertebral fractures (e.g. 19 cases in 2016, 38 cases in 2017, 45 in 2018 and 40 in 2019), comparing with the other fractures, without any statistical significance. An important significance was seen for frequency of pelvic bone injuries, when comparing 2016 with 2018 year (p=0.040). Furthermore, the complications seem to have a statistical significance when 2016 year was compared with all the other years (p=0.030, p=0.035, p=0.052). Regarding the biochemical and hematological analysis, a statistical significance was seen at Hb (when 2016 was compared with 2017 year, p=0.007 and 2018 year, p=0.001), Ht (when 2016 was compared with 2017, p=0.054 and 2018, p=0.002), PLT (when 2016 was compared with 2018 year, p=0.0004, and 2019 year, p=0.002) and ALT (when 2016 was compared with 2017 year, p=0.026, and 2018 year, p=0.026). The highest mortality was registered in 2019 (n=11), being statistically significant in comparison with 2016 year (p=0.030). About 109 patients were treated conservatively, and 64 by surgical interventions.

Conclusion: There is a lack of evidence for the best management in RPH, conservative approaching being reserved only for patients who are stable. Therefore, traumatic RPH complicated with bone fractures, especially lumbar vertebral fractures, represent a life-threatening condition, early diagnosis and correct treatment is of upmost importance.
Corelations and Interferences of Blood Alcohol Levels Measured By Cordebard and Gascromatography-Headspace Methods
Authors: Florentin Popa Marius , Lavinia Neculai-Cândea , Ștefan-Radu Comănici
Published: April 2021

Ethanol (ethyl alcohol) is an organic compound belonging to the alcohol class, being the main alcohol found in alcoholic beverages. It is a volatile, fl ammable and colorless liquid, with a characteristic odor, being considered one of the oldest drugs consumed by humans. Taking into account the prevalence of alcohol intoxication among drivers, and also among criminal offenders, it was deemed necessary to accurately determine the blood alcohol level detected in the biological samples taken from the suspects, considering the justice system requirements regarding the application of retributive measures in direct proportion to the detected blood alcohol level. The method currently used in Romania is the modified Cordebard Nitrochromic method, which comes with certain limitations, such as the variable homogeneity of the samples that induces sampling errors, thus resulting in blood alcohol levels below the real values. For these reasons, it is deemed necessary to align the methods of ethyl alcohol dosing at a national level and to the analytical requirements of the European Union exigencies, imposing the need to adopt a new method that eliminates as many sources of error as possible, a viable candidate at the moment being the Gascromatographic-Headspace method.
Particularities of a Fetus with Sirenomelia and Conceptual Separation from Caudal Regression Syndrome
Authors: Alina Martinescu , Daniel Corici Paul , Valentina Jianu , Valentina Francu
Published: April 2021

Sirenomelia is a very rare congenital anomaly, defined by partial or complete fusion of the lower limbs. Additional malformations may also occur, the phenotype being variable. Over time, sirenomelia has been considered the last stage of the evolution of caudal regression syndrome. However, the different characteristics in the context of the two syndromes, such as the single umbilical artery or, less often, two vessels, renal agenesis and the imperforate anus characteristic of sirenomelia as opposed to caudal regression syndrome where all three umbilical vessels are identified, along with sacral agenesis, led to the separation of the two entities. Sirenomelia is a multifactorial disease, with genetic heterogeneity, most cases being sporadic. Its pathogenesis is incompletely deciphered.

Thus, we present a case of sirenomelia, diagnosed after abortion at the end of the first trimester. The fetal autopsy gave us details of skeletal and visceral abnormalities. The sex of the aborted could not be determined due to the incomplete development of the genital tract.

To our knowledge, this is the first case reported in Constanta County. We hope that this presentation will be useful in trying to understand the causes of this condition.
On Rough Set Theory on Achieving High Quality Cable Material Production by Green Low Carbon Technology
Authors: Shuai Guoliang , Li Zhen , Zhang Diantao , Elhefnawey Maged , Li Li
Published: April 2021

As the second largest machinery industry, the energy-intensive cable industry not only creates a lot of economic value but also consumes a lot of energy. It is an inevitable requirement to promote the technological development of the industry in the new era to improve the quality and efficiency and realise industrial energy-saving and consumption reduction. In order to obtain good strength and conductivity, the metal rods of cable are usually heat-treated for several hours or even several days after the rods are extruded, this is a major energy consuming process in traditional production. Based on the background, this study adopted the energy-saving equal-channel angular pressing (ECAP) technology to replace the traditional heating treatment process, and converted the simple heat conduction with thermo-mechanical energy transfer, so as to realise the good strength and conductivity matching of the cable aluminum alloy material. In this study, energy-saving ECAP technology is used to replace the traditional heat treatment process, and heat-mechanical energy transfer is used to replace the simple heat conduction, so as to achieve good strength and conductivity matching of cable aluminum alloy material. The results show that the suitable ECAP process routes can improve the microstructure of aluminum alloy with higher strength and conductivity than the traditional heating process. The research results can be used for technology upgrading and low carbon production in cable industry due to the significantly time reduction of the energy-consuming heat treatment and the high-efficient obtainment of high-quality production.
Need for Cognitive Closure, Information Acquisition and Adoption of Green Prevention and Control Technology
Authors: Wu Qiong , Zhou Jing
Published: April 2021

In this paper, we use the OLS regression method to analyse the influencing mechanism of the NFCC on farmers’ adoption of green prevention and control technology and further verify the mediating effect of information acquisition. The results show that the NFCC has a direct effect on the adoption of green prevention and control technology, and information acquisition has a mediating effect. The first stage of cognitive closure has a more significant effect on farmers’ adoption of green prevention and control technology, information acquisition ability has a significant positive impact on farmers’ adoption of green prevention and control technology, and information acquisition has an incomplete mediating effect on the impact of cognitive closure on the adoption of green prevention and control technologies. This paper further studies and verifies the action path of two dimensions of the NFCC on farmers’ adoption of green prevention and control technology. The results have certain theoretical significance for expanding the knowledge of farmers’ green prevention and control technology behaviour and further enriching the research on farmers’ cognition.
Location and Strength of Malvolio Expression in Chinese Honeybee Reveals Its Potential Role in Labor Division
Authors: Ma Weihua , Meng Jiao , Zhen Xianyun , Zhao Huiting , Li Wanghong , Gao Ye , Jiang YuSuo
Published: April 2021

The malvolio (mvl) gene plays an important role in the transition from nursing to foraging in honeybees (Apis mellifera). Apis cerana cerana (A. c. cerana) is a subspecies of the eastern honeybee, well-known for its pollinator role throughout China. Although A. c. cerana shares many characteristics with A. mellifera, it is unclear whether Acmvl plays a similar role to Ammvl in foraging behavior. In this study, Acmvl expression was quantified during the transition from nursing to foraging in A. c. cerana. Acmvl protein production was also characterized in different tissues in bees from three behavioral groups. Finally, in situ hybridization was used to describe Acmvl expression patterns in forager bee brains. Acmvl expression was low early in life but then showed a major peak, which suggests its role in labor division. Examination of tissue type revealed that Acmvl expression was highest in the thoraxes of nurse bees and the heads of forager bees. In bee brains, Acmvl was selectively expressed in the somata of Kenyon cells in the mushroom bodies, optic lobes and antennal lobes. Taken together, these findings suggest that Acmvl plays a role in the nurse–forager transition of A. c. cerana.
Assessment of the morphometry of heads of normal sperm and sperm with the Dag defect in the semen of Duroc boars
Authors: Banaszewska Dorota , Andraszek Katarzyna
Published: April 2021

Introduction

The Dag defect is one of the primary morphological defects in sperm correlating with reduced fertility. This defect is found in the spermatozoa of many livestock species. The aim of the study was to assess the morphometry of the heads of normal sperm and sperm with the Dag defect in the semen of Duroc breeding boars.

Material and Methods

Sperm morphology was examined in ten ejaculates each from 12 Duroc boars. In total, 3,600 morphologically normal sperm and 838 sperm with the Dag defect were evaluated. The area, perimeter, length and width of the sperm head were measured and these basic morphometric parameters were used to calculate four additional shape indices characterising the sperm head, i.e. ellipticity, elongation, roughness and regularity.

Results

Sperm with this defect had markedly smaller heads, 0.32 μm shorter and 0.19 μm narrower than the heads of sperm with normal morphological structure. The heads of sperm with the Dag defect also had a 1.1μm smaller perimeter and a 2.5 μm2 smaller surface area than the heads of morphologically normal sperm.

Conclusions

The Dag defect is found in boar sperm irrespective of the age of the individual. It affects the morphology of the sperm head.
Investigation of the prevalence of Mycoplasma ovipneumoniae in Southern Xinjiang, China
Authors: Zhao Jin-yu , Du Yi-zhou , Song Ya-ping , Zhou Peng , Chu Yue-feng , Wu Jun-yuan
Published: April 2021

Introduction

It is very important to monitor the infection of Mycoplasma ovipneumoniae as a potential threat to the sheep industry. Southern Xinjiang is a major sheep breeding base in China, however, there is no relevant information concerning the infection of the region’s ovine stock with this bacteria at present. This study aimed to address this knowledge gap.

Material and Methods

A total of 824 nasal swabs and the lungs of six sheep that died of pneumonia were collected in four regions between 2018 and 2020. Primers specific for M. ovipneumoniae and universal ones for the genus were used for PCR. Sequencing was undertaken of 159 universal primer-positive samples (153 nasal swabs and 6 lungs) and of 84 specific primer-positive samples (80 nasal swabs, 20 per region; and 4 lungs, 1 per region). The lungs were also sampled for the isolation of M. ovipneumoniae. A phylogenetic tree based on partial sequences of the Mycoplasma 16S rRNA gene was built.

Results

The overall nasal swab positive rate for M. ovipneumoniae was 40.78%; the rate of animals older than 12 months was significantly different to those of younger sheep (< 3 months, 53.39%; 3 – 12 months, 46.01%; >12 months, 31.76%). Four strains of M. ovipneumoniae were isolated from six lungs. Phylogenetic analysis indicated their origin outside southern Xinjiang. Two other species were also detected: M. arginine and M. conjunctivae.

Conclusion

Our survey indicated that a high level of M. ovipneumoniae asymptomatic colonisation in sheep, especially in lambs, affects southern Xinjiang and also confirmed the existence of M. conjunctivae and M. arginine. Our results showed that the health of sheep in southern Xinjiang is facing a great threat, and relevant prevention and control measures should be strengthened.
Class struggle in the era of post-politics
Authors: Abalo Ernesto , Jacobsson Diana
Published: April 2021

This article addresses how class as a category of conflict and struggle is understood and shaped discursively in mainstream media today. We utilise a case study of how Swedish news media represents the long-lasting conflict in the Swedish labour market between the Swedish Dockworkers’ Union and the employer organisation, Sweden's Ports. Using critical discourse analysis, we show two ways in which class relations are recontextualised in three Swedish newspapers. One is through obscuring class and centring the conflict around business and nationalist discourses, which in the end legitimise a corporate perspective. The other, more marginalised, way is through the critique of class relations that appears in subjective discourse types. This handling of class, we argue, serves the reproduction of a post-political condition.
Anti-tumor agents: Design, Synthesis, and Biological study of N-Substituted-7-hydroxy-1-azacoumarin-3-carboxamide derivatives as potent cytotoxic agents
Authors: Bakare Safyah B.
Published: April 2021

Synthesis of ethyl 7-hydroxy-1-azacoumarin-3-carboxylate (3) was developed using ethyl-7-hydroxy coumarin-3-carboxylate and ammonium solution as the key synthons. Condensation of ethyl 7-hydroxy-1-azacoumarin-3-carboxylate with ammonium acetate and aniline to give N-substituted-7-hydroxy-1-azacoumarin-3-carboxamides (7-Hydroxy -1-azacoumarin-3-carboxamide (4) and N-phenyl 7-Hydroxy-1-azacoumarin-3-carboxamide (5)). Bromo derivative (N-phenyl 6, 8-dibromo-7-hydroxy-1-azacoumarin-3-carboxamide (6)) was obtained from halogenation of compound N-phenyl 7-Hydroxy-1-azacoumarin-3-carboxamide (5) with bromine in glacial acetic acid. N-phenyl-2,5-diacetoxy-6, 8-disubstituted-Quinoline-3-carboxamides (N-phenyl 2,7-diacetoxy-Quinoline-3-carboxamide (7) and N-phenyl 2,7-diacetoxy-6,8-dibromo-Quinoline-3-carboxamide (8)) were prepared via the acetylation of compounds 5 and 6 with acetic anhydride. Five compounds 4–8 were evaluated in vitro against more than one human tumor cell lines. Among the selected compounds, 6 showed the best in vitro cytotoxicity against the human cancer cell line; MCF-7 (with IC50 = 10.12 μM). In addition, cell cycle analysis of compound 6 demonstrated cell cycle arrest at G2/M phase and Pre-G1 apoptosis.
The Importance of the World Kidney Day World Kidney Day – 11 March 2021 – Living Well with Kidney Disease
Authors: Polenakovic Momir H. , Dohcev Saso , Rambabova-Bushljetik Irena , Gjorgjievski Dusko , Spasovski Goce
Published: April 2021

World Kidney Day (WKD) is a global campaign to raise awareness of the importance of our kidneys to overall health and to reduce the frequency and impact of kidney disease and associated health problems worldwide. Kidney disease is a non-communicable disease (NCD) and currently affects around 850 million people worldwide. One in ten adults has chronic kidney disease (CKD). The global burden of CKD is increasing, and is projected to become the 5th most common cause of years of life lost globally by 2040. CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume 2–3% of the annual healthcare budget in high-income countries. Crucially, kidney disease can be prevented and progression to end-stage kidney disease can be delayed with appropriate access to basic diagnostics and early treatment. This year World Kidney Day continues to raise awareness of the increasing burden of kidney diseases worldwide and to strive for kidney health for everyone, everywhere. During the pandemic with COVID 19 patients kidneys are also damaged, apart from the respiratory tract and other organs. It can lead to an increase in acute renal failure and consequent chronic kidney insufficiency, as well as number of deaths. Therefore, it is important to evaluate the renal function in each patient with COVID 19 virus. In the Republic of North Macedonia from 2006 to present day nephrologists and other medical personnel devoted to the early diagnosis, prevention and treatment of renal disease have participated in the activities of the World Kidney Day. These activities were supported by the Macedonian Society of Nephrology, Dialysis, Transplantation and Artificial Organs, the Department of Nephrology at the Medical Faculty, the Macedonian Academy of Sciences and Arts, the Government of the Republic of North Macedonia, non-governmental nephrology organizations (NEFRON) and the media. There were lectures and presentation devoted to the various theme of the WKD, publications in journals, as well as activities for examination of the renal function of patients in the medical centers. The activities during the WKD contributed to the improvement of the nephrological protection of the citizens of the Republic of N. Macedonia.
2-Methoxyestradiol Attenuates the Development and Retards the Progression of Hypoxia-And Alpha-Naphthylthiourea-Induced Pulmonary Hypertension
Authors: Tofovic Stevan P. , Zhang Xinchen , Jones Tom J. , Petruševska Gordana
Published: April 2021

Pulmonary arterial hypertension (PH), a progressive, incurable, and deadly disease, predominantly develops in women. Growing body of evidence suggest that dysregulated estradiol (E2) metabolism influences the development of PH and that some of the biological effects of E2 are mediated by its major non-estrogenic metabolite, 2-metyhoxyestradiol (2ME). The objective of this study was to examine effects of 2ME in chronic hypoxia (CH)-induced PH and alpha-naphthylthiourea (ANTU)-induced acute lung injury and PH. In addition, we investigated the effects of exposure to different levels of CH on development of PH. Chronic exposure to 15% or 10% oxygen produced similar increases in right ventricle peak systolic pressure (RVPSP) and pulmonary vascular remodeling, but oxygen concentration-dependent increase in hematocrit. Notably, right ventricle (RV) hypertrophy correlated with level of hypoxia and hematocrit, rather than with magnitude of RVPSP. The latter suggests that, in addition to increased afterload, hypoxia (via increased hematocrit) significantly contributes to RV hypertrophy in CH model of PH. In CH-PH rats, preventive and curative 2ME treatments reduced both elevated RVPSP and pulmonary vascular remodeling. Curative treatment with 2ME was more effective in reducing hematocrit and right ventricular hypertrophy, as compared to preventive treatment. Single ANTU injection produced lung injury, i.e., increased lungs weight and induced pleural effusion. Treatment with 2ME significantly reduced pleural effusion and, more importantly, eliminated acute mortality induced by ANTU (33% vs 0%, ANTU vs. ANTU+2ME group). Chronic treatment with ANTU induced PH and RV hypertrophy and increased lungs weight. 2-ME significantly attenuated severity of disease (i.e., reduced RVPSP, RV hypertrophy and pulmonary vascular injury). This study demonstrates that 2ME has beneficial effects in chronic hypoxia- and acute lung injury-induced PH and provides preclinical justification for clinical evaluation of 2ME in pulmonary hypertension.
Posterior Urethral Valve and Prenataly Resolved Multicystic Dysplastic Kidney
Authors: Aluloska Natasha , Palchevska Snezana , Simeonov Risto , Gucev Zoran , Tasic Velibor
Published: April 2021

Multicystic dysplastic kidney is a rare congenital anomaly of the kidney and urinary tract. The association with the posterior urethral valve is also very rare. Here we present a patient with both entities and prenatal resolution of the cysts.

A 10-week old baby was referred for nephrourological work up due to prenatal diagnosis of the left multicystic kidney. He had serial US scans during the pregnancy. Immediately before delivery the cysts were not seen (prenatal resolution). There were no extrarenal anomalies. The first postnatal ultrasound scan revealed normal sized right kidney without dilatation of the pelvicalyceal system. The bladder had normal thickness of the wall. Technetium-99m dimercaptosuccinic acid scan showed no activity on the left side, and the right kidney appeared normal. At two months of age, a poor urinary steam was observed and additional urologic work up was indicated on clinical suspicion of PUV. Voiding urethrocystography revealed posterior urethral valve and the baby underwent cytoscopic valve resection.

Conclusion: We present a rare association of two congenital anomalies of the kidney and urinary tract with prenatal involution of the multicystic dysplastic kidney that is extremely rare event as seen in our case. Presence of posterior urethral valve must be suspected in a male baby with a poor urinary stream even when his ultrasound scan of urinary system appears normal.
Testing of Priorities in the Research of Cultural Heritage in Slovakia’s Depopulated Regions
Authors: Murin Ivan
Published: April 2021

Along with the dynamics of findings of several scientific disciplines of the recent decades, the mechanisms and processes of culture transmission seem to be much more apparent. The knowledge about cultural heritage and the inheritance of culture produced in this way have led to the creation of several platforms of critical cultural heritage. Anthropological and ethnological findings significantly enrich these multi-disciplinary environments where the criterion of a living cultural heritage is becoming generally accepted. In this light, the Arts and Humanities Research Council (AHRC) created a working group in 2019 with the aim to prepare an innovated Strategic Research Agenda (SRIA) for the submission of European projects in the field of cultural heritage (JPI CH). The working group invited Slovak and Czech researchers to reflect on the knowledge from the Central European research area in order to define the research topics for the priority Cultural Heritage and People. The research on the testing of the priority and clarification of the impacts of the depopulation of cultural regions on cultural heritage was conducted at selected locations of the Hont, Novohrad and Malohont regions. The key indicators for justifying the inclusion of the research topicThe impact of the depopulation of EU regions with cultural heritagein SRIA include ethnographic information, historical demographic data and the modelling of the transmission of cultural heritage content to the next generations.
Long-Term Dynamics of Trophic State Indicators in Phytoplankton of the Cooling Reservoir of a Nuclear Power Plant
Authors: Novoselova Tatiana , Barinova Sophia , Protasov Alexander
Published: April 2021

The dynamics of long-term indicators of trophicity in the cooling pond of a nuclear power plant in Ukraine was analyzed by phytoplankton biomass and bioindicators of trophicity. Greater species richness correlated with the number of species-indicators of greater trophicity. During the contourization processes caused by the introduction of filter-feeding mollusks and changes in the operating mode of the nuclear power plant, there was a decrease in the abundance of phytoplankton and trophic state. During decontourization, there was a sequential “return” of previously eliminated taxa and the restoration of the number of indicator species.