bluuebunny/crossref_metadata_2025 huggingface dataset:
Upper (in the pons Varolii) decussation of the motor (pyramidal) pathways and their relation to the nuclei of the pons Varolii and to the nuclei of the cranial nerves in some rodents
Authors: Korolkov Pavel Y.
Published: February 2022

Working on the central nervous system and using the Golgi method for staining it, as early as 1896 I had the opportunity to obtain microscopic preparations on which it was easy to verify that the fibers of the motor pyramidal bundles, passing through the pons Varolii, on their way separate collateral fibers from themselves to the nuclei of the pons Varolii.

Since that time, working according to the same method, I have been able to obtain in some animals an isolated coloration of the pyramidal tracts and on such preparations to observe a partial decussation of the motor (pyramidal) tracts in the upper third of the Varolii pons, and in addition I was able to trace the collateral fibers of the motor tracts towards cranial nerve nuclei.
On the difficulty of examination in epileptic psychoses and the connection of a dream with a crime
Authors: Sergeev Leonid A.
Published: February 2022

On November 29, 1884, the peasant Nikolai V. stabbed to death D., a worker at a potash factory rented by the merchant G. The murder, as the investigation found out, took place under the following circumstances:

On November 28, 1884, in the evening, the peasant Nikolai V. came to Fyodor N., who lived at the factory, and asked if the part of the land belonging to G., which his uncle Vasily wanted to buy, had been sold. It was late at night, Nikolai V. asked him to spend the night, which was allowed. V. went to bed in the kitchen, where the worker Dmitry P. stayed with him. There was no one in the kitchen except for the two of them. At night, Nikolai V. woke Fedor N. by knocking on the door and said that there were thieves walking around in the yard. N. jumped up, grabbed a single-barreled gun and ran out into the yard with it. Seeing no one there, he wanted to scare the thieves and fired, but there was a misfire, and he returned to the canopy. When he approached the porch of his apartment, his wife came out to meet him and gave him a revolver, and he handed her the gun. When she saw V.: and asked "what are you standing here and not going to look for thieves", he answered her "I'm afraid of something."
Bonché G. A case of subacute combined sclerosis due to anaemia perniciosa. Un cas de sclérose combinée subaigue associée a l'anémie perniciuese. —Journal de neurologie. 1909, no. 5.
Authors: Likhnitsky V.
Published: February 2022

The first signs of the disease appeared about 3 years ago; at present, the nervous system has the following symptoms: paraplegia spastica, increased tendon reflexes; lack of disorders from the sphincters. Disorders of skin sensitivity are insignificant: a slight decrease in tactile sensitivity; pain and temperature are normal. Sharp disorders of the muscular and articular sense, ataxia of the arms and legs.
A. M. Virshubsky. A case of primary peripheral disease of the auditory nerve. — Practical Physician. 1909 No. 37.
Authors: Bogatyrev V.
Published: February 2022

The author gives an anatomical and physiological analysis of a case from his own practice, where, after a bruise on the left half of the head, symptoms of damage to the auditory nerve, the upper branch of the facial and chordae tympani of the left side appeared. The author considers hemorrhage to be the most likely cause of damage to the auditory nerve, but he also admits another explanation: the otolith could come off from its place of attachment (due to concussion) and, floating in the endolymph, irritate the nerve endings n. vestibularis with every movement of the head.
A.M. Evlakhov. Genius-artist as antisocial. — Varsh. Univers. news. 1909-VII-VIII-IX
Authors: Bogatyrev Y.
Published: February 2022

The view is still widespread that a great artist, by his very nature, should be especially sensitive to issues of a social nature and that his worldview should be at least at the level of the progressive aspirations of society. However, an analysis of the facts, even a superficial one, leads to a different conclusion. The author lists the great artists of the word of different times and proves that they were not people with a broad social outlook, even moremany of them differed in this respect by extreme backwardness from their contemporary society; on the other hand, there is not a single outstanding artist who would be at the same time an active political or public figure, or at least have a view corresponding to such activity.
Dr. Weygand. Degrees and types of children's dementia. Zeitschr. f. d. Erforschung und Behandlung d. jugendlich. Schwachsinns, V. II, 1908
Authors: Kovalevsky Pavel I.
Published: February 2022

In his report at the congress of hygiene and demography, the author argues that the modern classification of mentally abnormal children into idiots, stupid, insufficient, backward and incapacitated does not withstand criticism from the point of view of therapy. It is more or less successful from the point of view of the charity of these children, but it generalizes the varieties too much. The author proposes a classification of abnormal children.
Margit Revesz. The ability of calculus in incapable children and a more accurate assessment of it. Die Rechenfähigkeit der Schwachbefähigkeit und deren genauere Wertung.—Zeitschr. f. d. Erforschung und Behandlung d. jugendlichen Schwachsinns, B. II, 1908
Authors: Kovalevsky Pavel I.
Published: February 2022

It is not difficult to draw a line between average normal children and retarded children who require placement in a special school for retarded children. It is much more difficult to divide into groups of children recognized as retarded. The author, on the basis of studies of retarded children in an auxiliary school in Budapest, believes that mathematical exercises, oral and written, in the four rules of arithmetic can serve as a convenient criterion in this regard. This takes into account both the ability of numeration, the speed of decision and the quality of work. Using this method, retarded children can be divided into three categories: quite successful, average and weak.
Dr. Robertson. Experimental progressive paralysis The experimental production of general paralysis. — The journal of mental science, 1909
Authors: Kovalevsky Pavel I.
Published: February 2022

Six years ago, the author published a paper on the development of progressive paralysis in rats after they had ingested a culture of diphtheria bacilli isolated from the bronchi of a progressive paralytic. These investigations were verified by the author and Mac Bae and were fully confirmed, and in the nerve elements were found changes characteristic of progressive paralysis. Finally, the author recently tested the effect of culture bacil. paralyticans longus in rabbits, with positive results in only one case. Dr. O'Brien experimented with the injection of diphtheria bacilli against paralytics in rats, dogs and goats and got: hibernation, stupor, muscular tension, ataxia, partial paralysis, congestive attacks and death.
Dr. Williamson. Bacillus paralyticans. - The journal of mental science, 1909
Authors: Kovalevsky Pavel I.
Published: February 2022

The author checked Robertson's research on his causal research on progressive paralysis and found that the bacillus described by Robertson and Mc. Bae does exist. They are too common and are found in the normal throat and in the skin. They are really pathogenic, moreover, the disease they produce is in the majority of a chronic nature. These bacilli act destructively on the blood serum. They produce an immune body and can act as an antigen. This antigen can also be produced at the site of the disease.
A. Rodiet. The influence of a vegetarian regimen on the character and temperament of epileptics. De l'action du regime vegetarien zur le caractére et le temperament des épileptiques. — Journal de neurologic. 1909, no. 12
Authors: Likhnitsky V.
Published: February 2022

At the beginning of the article, the author cites excerpts from the monograph by prof. A. Gautieron nutrition and mode, in which a number of examples are collected showing the influence of animal and vegetable food, both on the character of individuals and entire nations and even animals. Next, Rodiet summarizes his observations on 11 epileptic women he observed at the Saint-Jon Hospital. Three of them had an ordinary, calm, equal character, the remaining 8 represented features characteristic of epilepsy: they were sometimes gloomy and silent, sometimes they became irritable and aggressive.
R. von den Velden. Observations on epileptics. The value of sodium chloride in some forms of epilepsy. Ein Beitrag zur Bedeutung des Chlornatrium fur gemisse Formen der Epilepsie—Deutsehe Zeitschrift für Nervenheilkunde, Bd. 38, 1909
Authors: Likhnitsky V.
Published: February 2022

At the beginning of the article, the author dwells on a whole series of studies on the displacement of chlorides in the body by bromides, studies that led to the recognition of the specific, toxic effect of bromine on nerve elements. By directly stimulating the gray matter of the brain of trepanned animals, Rosentach confirmed these observations with experimental data. But animal experiments published by Wyss in 1908 suggest that the effect of bromine therapy does not depend on the medicinal properties of bromine itself, but on the fact that bromine salts displace from the body part of the sodium chloride, which is harmful to epileptics.
R. Julien. Electrodiagnostics and electrotherapy of neuritic post-typhoid paralysis. Electrodiagnostic et electrotherapie dans les paralysies névriqutics post-typhiques. Archives d'electricité medical. November 1909
Authors: Likhnitsky V.
Published: February 2022

Neuritis that appears after typhoid fever, the author considers a phenomenon far from frequent: for 45 neuritis of non-traumatic origin, there were only 3 such cases. In the 12th year, she suffered from typhoid fever; severe form, with relapse, lasting 3 months. During the relapse, paralytic phenomena appeared in the lower extremities; pain in the legs, severe at the beginning, subsequently disappeared.
Lallement. Electrotherapy of functional seizures. Electrotherapie dans les spasmes fonctionelles.—Arch. d'Electric. Medicale, 1909. p. 138
Authors: Likhnitsky V.
Published: February 2022

Considering the various uses of electricity for occupational convulsions proposed by Erb, Larat, Vigouroux, Onimus, and others, the author comes to the conclusion that none of them is suitable for all cases, but that a combination of various methods gives the most successful results. Based on these considerations, he proposes the following treatment plan.
Dr. Kohn. Cyclothymia. La cyclothymic. 1909
Authors: Kovalevsky Pavel I.
Published: February 2022

The content of the author's monograph is a description of a special state of mind, characterized by its periodicity. According to his observations, there is a special psychopathic organization that manifests itself in mood disorders. These disorders are intermittent and circulatory, indicating their instability. This will be in the true sense of the cyclotypic organization. It manifests itself mainly on hereditary soil. Its manifestations begin in adolescence and have different degrees: mild, moderate and strong. A mild degree is expressed only by an increase in the normal state.
Chronicle of the Society of Neurologists and Psychiatrists at the Imperial Kazan University dated October 28, 1909
Authors: Darkshevich Livery O. , Sholomovich Alexander S.
Published: February 2022

Presided over by prof. V. P. Osipov under Secretary A. S. Sholomovich. Actions were present. Members: prof. N. A. Mislavsky, Dr. Polumordvinov, Pervushin, Donskov, Favorsky, Veselitsky, Bolberg, Chalusov, Klyachkin, Glushkov, Osipova V. N. Guests: Dr. Khomyakov, Shibkov, Tushnov, Golovin, Perimov, Nikolskaya and about 50 outsiders, ch. arr. students.At the beginning of the meeting, the chairman prof. V.P. Osipov delivered a speech in memory of prof. Caesar Lombroso, briefly describing his activities in psychiatry and anthropology; at the suggestion of the chairman, the memory of Lombroso was honored by standing up.
Construções em movimento – Olhar, ver, sonhar. Sonhar e ver / Buildings in motion – Looking, seeing, dreaming. Dream and see
Authors: Steinmetz Elisangela Da Rocha
Published: February 2022

Resumo: O presente artigo visa abordar o modo como os contos da obra Histórias de ver e andar, de Teolinda Gersão, e os contos de La sueñera, de Ana María Shua, manifestam, especialmente, através do tema do olhar a percepção de distintos aspectos, que podem (ou não) conduzir a determinado movimento. Para tal são referências, entre outros, Cortazar e Merleau-Ponty. Dessa forma, observam-se e questionam-se alguns limites da percepção entre o real, o onírico e o ficcional.Palavras-chave: olhar; sonhar; Teolinda Gersão; Ana María Shua; literatura.Abstract: This article aims to address the way in which the tales of Teolinda Gersão’s book Histórias de ver e andar and the tales of La sueñera, by Ana María Shua manifest, especially, through the theme of looking, the perception of different aspects, which they may (or may not) lead to a certain movement. For this, references are, among others, Cortazar and Merleau-Ponty. In this way, some limits of perception between the real, the dreamlike and the fictional are observed and questioned.Keywords: to look; to dream; Teolinda Gersão; Ana María Shua; literature.
Lugares de memória: significando os símbolos em “As tardes de um viúvo aposentado”, de Teolinda Gersão / Places of memory: signifying the symbols in “As tardes de um viúvo aposentado”, by Teolinda Gersão
Authors: Campello Priscila Campolina de Sá , Oliveira Bruna Gabriele
Published: February 2022

Resumo: O presente artigo teve como objetivo identificar e discutir como os lugares de memória são construídos na narrativa por meio de símbolos presentes na casa e no dia a dia do protagonista, como cemitério, lápide, fotos antigas, entre outros. Para o corpus deste trabalho foi escolhido o segundo conto presente na coletânea de contos A mulher que prendeu a chuva e outras histórias (GERSÃO, 2007), nomeado “As tardes de um viúvo aposentado”, de Teolinda Gersão, narrado em terceira pessoa, cujo enredo corresponde à rotina de um viúvo aposentado que está em fase de luto pela morte recente de sua esposa. A memória, a velhice e a solidão são temas que serão explorados na análise para alcançar o objetivo proposto. Autores como Candau (2011), Vieira (2013), Pinheiro (2009), Santos e Amaral (1997) serão utilizados como aporte teórico com contribuições valiosas para a discussão.Palavras-chave: literatura de autoria feminina; luto; memória; símbolos; velhice.Abstract: This article intends to identify and analyze how the places of memory are constructed in the narrative through symbols present at the protagonist’s home and daily life, such as cemetery, gravestone, old pictures, among others. For this purpose, we have chosen the second short story from Teolinda Gersão’s (2007) collection of stories A mulher que prendeu a chuva e outras histórias, entitled “As tardes de um viúvo aposentado”. This 3rd person narrative focuses on a retired widower’s daily routine, who is mourning his wife’s recent death. Memory, old age, and loneliness are themes which will be discussed in this analysis in order to develop our proposal. Authors such as Candau (2011), Vieira (2013), Pinheiro (2009), Santos and Amaral (1997) will be our theoretical support with their valuable contributions to our discussion.Keywords: literature of female authorship; grief; memory; symbols; aging.
Alice e o enigma do desejo do outro: “O que ele quer de mim?” – e, assim, ela se livra do desejo de desejar / Alice and the riddle of the desire of others: “What does he want from me?” and thus she gets rid of the desire to desire
Authors: Faria Ângela Beatriz De Carvalho
Published: February 2022

Resumo: Teolinda Gersão, em “Alice in Thunderland”, conto inserido na coletânea Alice e outras mulheres (2020), ao revisitar de forma singular a ficção de Lewis Caroll, liberta a personagem do livro que a aprisionara. A Alice atual, inscrita no signo da temporalidade, recupera a sua identidade civil – Alice Liddell – e, ao adquirir uma voz própria, torna-se capaz de desvendar “as zonas de sombra e os mistérios das relações humanas”. Alice rompe o silêncio a que fora submetida e desvenda o enigma do próprio desejo e do desejo do Outro. Ao denunciar o abuso sofrido, durante a sua infância, conseguirá superar os resquícios do ressentimento e atravessar para o outro lado do espelho. O artigo pretende discutir tais questões a partir da leitura de ensaios e/ou obras da autoria de Maria Rita Kehl, Eugène Henriquez, Marilena Chauí e Roland Barthes entre outros.Palavras-chave: Alice in Thunderland; Teolinda Gersão; ressentimento; desejo; intertextualidade; ficção portuguesa contemporânea.Abstract: Teolinda Gersão, in “Alice in Thunderland”, a story in the collection Alice e outras mulheres (2020), by revisiting Lewis Caroll’s fiction in a unique way, frees the character from the book that had imprisoned her. The present-day Alice, inscribed in the sign of temporality, recovers her civil identity – Alice Lidell – and, by acquiring a voice of her own, becomes capable of unveiling “the shadow zones and mysteries of human relationships.” Alice breaks the silence to which she had been subjected to and unveils the enigma of her own desire and that of the Other. By denouncing the abuse she suffered during her childhood, she will be able to overcome the remnants of resentment and cross over to the other side of the mirror. The article intends to discuss such issues from the reading of essays and/or works by Maria Rita Kehl, Eugène Henriquez, Marilena Chauí and Roland Barthes, among others.Keywords: Alice in Thunderland; Teolinda Gersão; resentment; desire; intertextuality; contemporary Portuguese Fiction.
Vidro do mesmo vidro: visualidade e transparência na poética de Rosa Maria Martelo Vidro do mesmo vidro: Visuality and Transparency in Rosa Maria Martelo’s Poetic
Authors: Brito Nuno
Published: February 2022

Resumo: Este estudo tem como objeto a criação da imagem poética na produção literária de Rosa Maria Martelo, os seus processos e recursos num amplo diálogo intertextual e interartístico com outras formas de criação da imagem verbal e visual, assim como salientar o seu contacto com a tradição literária e artística do passado, aprofundar a sua relação central Imagem-Velocidade e mostrar o seu forte carácter de experimentação e hibridez de género.Palavras-chaves: Rosa Maria Martelo; imagem poética; matéria.Abstract: This study is aimed at the creation of the poetic image in Rosa Maria Martelo’s literary production, its processes and resources in a wide inter-textual and inter-artistic dialogue with other forms of creating the verbal and visual image. Furthermore, this essay intends to highlight the contact of this creation with the literary and artistic tradition of the past, to deepen its central relationship Image-Speed and to show its strong experimental character and genre hybridism.Keywords: Rosa Maria Martelo; poetic image; matter.
“Editar Pessoa é e sempre será uma tarefa de Sísifo...”: entrevista com o professor Jerónimo Pizarro / “Editar Pessoa é e sempre será uma tarefa de Sísifo...”: interview with professor Jerónimo Pizarro
Authors: Silva Marcelo Alves da , Pereira Pedro Martins Cruz de Aguiar
Published: February 2022

Nessa breve entrevista que fizemos com Jerónimo Pizarro - docente e pesquisador da área das literaturas de expressão portuguesa, da Universidad de Los Andes, e editor da obra de Fernando Pessoa -, propusemos ao professor um conjunto de 8 perguntas que consideramos fundamentais para refletirmos, dentre alguns aspectos: os caminhos que levaram Pizarro a se interessar pelo estudo da obra do poeta português; as múltiplas e díspares existências das edições das obras de Fernando Pessoa; a conjugação entre crítica literária e crítica textual para melhor compreensão das particularidades da poética pessoana; a metamorfose dos ambientes críticos dedicados aos textos de Pessoa; e a trajetória - material e digital - da obra do poeta português como desafio à fruição estética e aos estudos vindouros. Cremos que a entrevista é um grande contributo para todos os pesquisadores que ensinam e investigam a obra de Fernando Pessoa e de seus heterônimos.
Roles of Timeless in DNA Repair and Carcinogenesis
Authors:   , Brewster Tylor L. , Noguchi Eishi
Published: February 2022

Timeless, an integral component of the replication fork protection complex, stabilizes the replication fork in response to DNA damage. Timeless is also involved with the maintenance of genomic integrity through its interaction with downstream targets that aid in checkpoint regulation, DNA repair, and DNA replication. Recent studies have shown that Timeless interacts with PARP1 to promote DNA repair via homologous recombination. Timeless also interacts with DDX11 to facilitate replication at hard-to-replicate regions of the genome. Studies have suggested the role of Timeless in cancer progression; Timeless is frequently overexpressed in various types of cancers, and this high expression is associated with poor patient prognosis and increased metastasis. Furthermore, Timeless confers resistance to chemotherapeutic drugs such as cisplatin and serves as a marker for tamoxifen resistance. However, the mechanisms by which Timeless regulates DNA repair and carcinogenesis are not well understood. In this study, we aimed to understand the role of Timeless in genome maintenance and cancer phenotypes. We performed mutational analysis of Timeless to determine the role of Timeless-PARP1 interaction in DNA repair and Timeless-DDX11 interaction in DNA replication. We found that Timeless depletion leads to growth inhibition and a significant increase in senescence-associated phenotypes. Considering that senescence is generally regarded as a tumor-suppressive mechanism, our findings suggest that Timeless promote survival of cancer cells. Future studies would include assessing the effects of Timeless mutations in DNA replication, repair, and cancer phenotypes. We expect that these studies will serve as a stepping-stone to develop effective strategies for cancer therapy.
Cell-Based Readouts of Copper-Modulated CK2 Kinase Activity
Authors:   , Li Rongrong , Strochlic Todd I
Published: February 2022

Casein kinase 2 (CK2) is a heterotetrameric serine/threonine kinase that phosphorylates hundreds of substrates to regulate diverse cellular processes ranging from signal transduction to cell cycle progression and cell proliferation. In addition to its high degree of promiscuity, another unusual characteristic of CK2 is its apparent constitutive activity: in contrast to the tight regulation seen in most other kinases, no definitive mechanism for regulating CK2 kinase activity has been defined. An emerging paradigm in kinase biology is regulation of catalytic activity by binding to copper. Indeed, the MAPK pathway kinases MEK1/2 and the autophagic kinase Ulk1/2 are copper-dependent, and data from our lab indicates that CK2 is likewise a copper-modulated kinase. Here we have employed a pharmacological approach to investigate the role of copper in regulating CK2 kinase activity in human cancer cells. We show that Cu-ATSM, a cell-permeable copper compound, enhances CK2 kinase activity in vitro and in cells as assessed by Western blotting using phospho-specific antibodies to monitor CK2 catalytic activity. Moreover, we observed phosphorylation of the catalytic [alpha] subunit of CK2 in response to increased intracellular copper. Collectively, these results demonstrate that copper plays a role in modulating CK2 kinase activity in cells and suggests a possible regulatory mechanism of CK2 kinase activity through copper-induced catalytic [alpha] subunit phosphorylation.
Activity and substrate specificity of cobinamide/cobamide amidohydrolase CbiZ in diverse bacteria
Authors:   , Kantner Daniel Stephen , Beld Joris
Published: February 2022

Cobamides, including vitamin B12 (cobalamin), are essential micronutrients for many organisms but are only biosynthesized by some archaea and bacteria. Cobamide variants differ in the identity of the lower base of the nucleotide loop. Many cobamide-dependent enzymes exhibit specificity for certain variants, which can impart specific biosynthetic or nutritional cobamide requirements. Some organisms can import cobamides and use them directly, while others can complete biosynthesis from imported intermediates (salvaging) or convert an imported cobamide to another variant (remodeling). One remodeling pathway involves amidohydrolase CbiZ, which cleaves the nucleotide loop from a cobamide or biosynthetic intermediate cobinamide, allowing for incorporation of a different lower base. CbiZ has only been studied in some archaea and Rhodobacter sphaeroides. Whereas archaeal CbiZ cleaves cobalamin, the Rhodobacter homolog cleaves pseudocobalamin. With the presence of dozens of other cobamides in different environments, we hypothesized that other CbiZs have different substrate specificities. With no structure or active site known, we used protein similarity networks to identify clusters of divergent CbiZ sequences. In vitro and in a heterologous expression model, we show that the CbiZs from Bacillus badius and Rossellomorea vietnamensis cleave cobinamide and the cobamides cobalamin, pseudocobalamin, and p-cresolylcobamide. We also show that two CbiZs from Sporomusa ovata demonstrate distinct cobamide specificities in a heterologous expression model. Additionally, we report that B. badius requires exogenous DMB-ribose to complete cobalamin biosynthesis and that R. vietnamensis salvages cobinamide and DMB-ribose to biosynthesize cobalamin. These results expand our understanding of CbiZ-mediated remodeling, which plays an important role in microbial communities.
Librería Java para análisis y simulación de sistemas lineales
Authors: Blanch Costa Jordi , Costa Castelló Ramón
Published: February 2022

Este proyecto presenta el diseño, implementación y algunos ejemplos de uso de una librería JAVA pensada para el análisis y simulación de sistemas lineales. Se ha diseñado pensando en que sea fácilmente integrable con Easy Java Simulations. El uso combinado de ambas herramientas facilita el desarrollo de laboratorios virtuales y remotos.
Control MPC basado en un modelo LTV para un control de seguimiento de trayectoria
Authors: Mata Sara , Zubizarreta Asier , Nieva Ione , Cabanes Itziar , Pinto Charles
Published: February 2022

Este artículo presenta una aplicación de seguimiento de trayectoria para vehículos mediante Control Predictivo basado en Modelo (MPC) con un modelo Linealmente Variable en el Tiempo (LTV). El sistema de control está diseñado para garantizar un correcto seguimiento de la trayectoria bajo ciertos criterios de confort. Por lo tanto, no sólo se considera el error lateral, sino también el error de orientación respecto de la trayectoria objetivo. Además, también se consideran restricciones estrictas en la señal de control, en la variación de la señal de control y en el error lateral de seguimiento de la trayectoria. Se exponen resultados experimentales para diferentes tipos de trazados, concluyendo con un circuito. En todos los casos se considera un amplio rango de velocidades incluyendo elevadas velocidades.
Evaluación de manipuladores robóticos mediante métricas de calidad del agarre
Authors: Rubert Carlos , Morales Antonio
Published: February 2022

Durante los últimos años, se han realizado grandes avances en el desarrollo de manipuladores robóticos. Distintos métodos han sido utilizados para diseñarlos, permitiéndolos dividir en dos grupos, pinzas robóticas y manos artificiales antropomorfas. En este artículo se utilizan un conjunto de métricas de calidad, ampliamente utilizadas en robótica, para analizar agarres, con el objetivo no sólo de comparar estos dos conceptos de diseño, sino también las limitaciones de las métricas a la hora de evaluarlos. Distintos manipuladores de ambos estilos de diseño y varios objetos son utilizados en un entorno de simulación donde las capacidades para coger son analizadas. Los análisis estadísticos sobre estos resultados permitirán estableces la dependencia de las métricas en el tipo de manipulador, pero también realizar evaluaciones comparativas en ambos métodos de diseño, proporcionando una evaluación que de como resultado un mejor rendimiento para realizar agarres.
Sorafenib combined with radiation therapy for advanced hepatocellular carcinoma with portal and hepatic vein invasion extending to the inferior vena cava: a complete response case according to modified RECIST criteria
Authors: Cho Yuri , Kim Bo Hyun , Kim Tae Hyun , Koh Young Hwan , Park Joong-Won
Published: February 2022

The prognosis of patients with advanced hepatocellular carcinoma (HCC) with tumor thrombus extending to the inferior vena cava (IVC) is extremely poor. Herein, we present a rare case of advanced HCC that was treated with sorafenib and radiotherapy, leading to complete remission. This patient had a 9 cm infiltrative HCC occupying almost the entire left lobe with a tumor thrombus extending through the hepatic vein, IVC, and left portal vein. The patient received 400 mg sorafenib twice daily. One year after the start of sorafenib, intensity-modulated radiation therapy for viable HCC and tumor thrombus was performed with a dose of 5,500 cGy. Twenty-seven months after the starting date of sorafenib, there was no intratumoral arterial enhancement, which suggested a complete response according to the modified RECIST criteria. This case suggests that the combination of sorafenib and radiotherapy might provide clinical benefits in patients with advanced HCC with IVC tumor thrombus.
"This Class Was Highly Useless": Reformulating an Unpopular Music Theory Course for Non-music Majors
Authors: Coelho A. S. Marques Igor
Published: February 2022

This essay first examines how a course of music theory for non-music majors at the University at Buffalo experienced a serious drop in popularity between 2016-2019, suggesting the following as contributing factors: snowballing complexity, overtaxing homework expectations, reliance on non-relatable repertoire, and lack of in-class music-making. Then, it recounts in detail how the adoption of a new syllabus addressed these particular issues and how the students reacted to these new methodologies, hoping to provide the reader with an example of an emerging inclusivity-focused paradigm in music theory pedagogy.
Can We Learn to Hear Multi-metrically?
Authors: Stover Chris
Published: February 2022

While certain strands of music-cogition studies suggest that we can only entrain to one metric stratum at a time, I contend that not only can we entrain to two or simultaneously, but that certain musicking practices (particularly from African and the African diaspora) require that one do so. This essay explores some scaffolded introductory activities for learning to do so through stepping, clapping, and singing.
Completeness and accuracy of death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015-2017
Authors: Mandasari Rosa Mutiara , Pidada IBG Surya Putra , TA Martiana Suciningtyas
Published: February 2022

Background: Ludira Husada Tama Hospital is one of privately-owned hospitals in Yogyakarta. Being classified as a type D hospital, the author aims to observe the implementation of writing death certificate in terms of completeness and accuracy. Objective: To know the completeness and the accuracy of death certificate on cause of clinical death at Ludira Husada Tama Hospital in 2015-2017 Method: This study is a descriptive-observational study using crosssectional method. This study was taken place at Ludira Husada Tama Hospital, Yogyakarta by taking the medical record of the patient who die in this hospital which have death certificate on cause of clinical death in 2015-2017. Result: The amount of medical record contains death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015-2017 that met inclusion and exclusion criteria is 55 data. In the completeness of death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015-2017, 98% is classified as fair and 2% is classified as poor. In the accuracy of death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015- 2017, the percentage of accuracy on the section I (a) is 62%, on the section I (b, c) is 22%, on the section I (d) is 20%, and on the part II is 11% accurate. Conclusion: In the completeness of death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015-2017, 98% is classified as fair and 2% is classified as poor. In the accuracy of death certificate on cause of clinical death at Ludira Husada Tama Hospital Yogyakarta in 2015-2017, the percentage of accuracy on the section I (a) is 62%, on the section I (b, c) is 22%, on the section I (d) is 20%, and on the part II is 11% accurate.
A prospective study of Knot, Ligature Pattern and other External Findings observed in various cases of Hanging in Allahabad; Uttar Pradesh
Authors: Kaul Archana , Sonkar Virendra Kumar , Rai Rajesh Kumar , Kumar Alok , Kumar Raj
Published: February 2022

Background: Hanging is caused by suspension of the body by a ligature encircling the neck. The person may use any article readily available for this purpose, like a rope, saree, belt, bed sheet etc. Most times, Ligature mark and material may be the only evidence available in deaths due to either hanging or strangulation. Their thorough examination and analysis is extremely helpful in differentiation and provide vital medicolegal information. Material and Method: Present study was conducted among the dead bodies brought to the mortuary of Swaroop Rani Nehru hospital MLN Medical College Allahabad. Out of 2654 cases autopsied during the study period from 01/05/2016 to 30/4/2017; 184 cases (6.93%) were caused by violent asphyxial death. Out of that 120 (65.2%) cases including hanging (94) and strangulation (26) were taken for study. Results and Conclusion: The young adults of the age group of 21-40 years contributed for majority of cases with 66(55%) of cases of hanging and 16(13.3%) of cases of strangulation. The position of knot was seen on the right side in 42(35%) cases. Duppatta was most commonly used ligature material 41(34.16%). The most common external finding was cyanosis seen in 84 (70%) and 26 (21.66%) cases of hanging and strangulation, respectively. Present study provides vital information for the Doctors, Police and concerned authorities in investigating cases of Hanging and strangulation.
Dermatoglyphics in dentistry: a review
Authors: Kadam Sonali , Biswas Debpriya , Vijayalaxmi Nimma , Landge Bhagyashree
Published: February 2022

Fingerprint analysis for personal identification is well known and is unique to all individuals and remains the same for a lifetime. The hand has become a powerful tool in the diagnosis of psychological, medical, genetic conditions. Dentistry is no exception has number of diseases which can be diagnosed using the study of finger prints described as dermatoglyphics. The present review describes peculiar changes in dental diseases and gives an insight to the supporting literature.
Correlation of Brain Weight with Cadaveric Weight, Length, and Cause of Death
Authors: Vedpathak Pritija R. , Bhise Sadanand S. , Nanandkar Sudhir D.
Published: February 2022

Individual patterns of growth vary widely because of differences in heredity and environment. Introduction: Human growth from infancy to maturity involves great body size changes and appearance, including the development of sexual characteristics. The growth process is not a steady one; at some times, growth occurs rapidly, at others slowly. Material and Method: Present study is the prospective examination of a total of 300 autopsy cases brought during the period from 2016-18. In this, 241 were males, and 59 were females. Result: The data of internal organ weights were statistically analyzed. They are grouped into gender, cadaveric body weight, and cadaveric body length. The cause of death is further grouped into natural and unnatural causes leading to death. Unnatural deaths are grouped into traumatic, asphyxia, and poisoning deaths. Data is analyzed by determining mean, standard deviation, maximum, and minimum. Conclusion: Brain weight is linearly related to cadaveric weight and cadaveric length. Internal organ weights are linearly related to cadaveric weight and cadaveric length.
Medical Negligence–Legal Narrative and Prevention in Malaysian Medical Practice
Authors: Zainal Hafizah , Razali Hazdalila Y. , Khan Jesmine , Islam Mohammed N.
Published: February 2022

Medical negligence cases in Malaysia are not far behind from other developed countries in terms of quantity and costs. The challenges of medical negligence in Malaysia have always been an enemy to both patients and doctors. Both parties may lose more than they gain from the adversarial adventure of medical litigation. Hence prevention of medical negligence is the best effort in ensuring the best medical practice for both parties. Practicing ethical medical practice and improving communication with the patient is some of the methods to avoid getting sued. If this fails, alternatives to medical litigation such as alternative dispute resolution in the form of mediation and no-fault compensation scheme. These alternatives may offer more to both parties rather than going through the litigation process.
Prevention of Sports Related Orofacial Injuries- A Review on Dental Perspective
Authors: Kausadikar Pranoti P. , Kadam Sonali G. , Ramaswami Easwaran , Nimma Vijayalaxmi , Murjani Bhavana K. , Suryawanshi Sandesh D. , Saju Reshma
Published: February 2022

The field of sports dentistry mainly deals with the prevention and management of sports-related to maxillofacial trauma. There are many potential challenges to the oral health of athletes including exercise-induced trauma, dental decay due to specialized diet, lack of awareness, oral dehydration and lack of prioritization for dental care. However, there is good evidence that some oral diseases are preventable by simple interventions with good efficacy. Hence dentists today must respond to these patient's specialized needs, providing them with the quality of care that they deserve. In this review article, we discuss the various preventive aspects of sports-related injuries and the impeccable role of dentist in preventing and managing the sport-related oro-facial injuries.
Sexual Abuse: Investigation of Rape, Sodomy, and Murder
Authors: Kumar Sharon D. , Saini Vishal
Published: February 2022

There are widely increased in sexual abuse that becomes a severe predicament of every society. It has not only put permanent stains on the deceased, but as well as her entire family into degrades and shame. The sensual abuse cases' progressive contribution was being targeted mostly on women, infants, and homosexuals, by the disparate manner of assault-style like sodomy and the killer is male. Sadly, many children become the sufferer of sex-related homicides perpetrated by the individual who are intended to protect them from evil. Four categories of rapists are power reassurance, power assertive, anger retaliatory, and anger excitation. It is necessary to bring justice to society and should fear the consequences the criminals will face. We present a case study that will bring about the important facts and figures of how forensic science helps give conclusions to the cases. In some situations. Offender profiling has been debate on recommending psychiatric and psychological analysis of the sexual offender in such despicable crime.
LETTER TO EDITOR
Authors: Singh Virendar Pal
Published: February 2022

Through this letter, I want to bring to your notice World Trauma Day. Every year, 17th October is celebrated as World Trauma Day as a reminder of the importance of saving and protecting lives during emergencies. This day highlights the increasing rate of accidents and injuries causing death and disability across the world and the need to prevent them. Trauma means any injury caused to the body, which may be caused due to multiple reasons like road traffic accidents, fall from height, fires, burns, violence and crimes. Road Traffic Accident (RTA) is a leading cause of trauma across the world. Every year, about 5 million people die from injuries across the world. In India, it is estimated that approximately one million people die and 20 million are hospitalized every year due to injuries.
Histopathological Evaluation of Burn Injury
Authors: Malik1 Anil Kumar , Khanna Kunal , Dhattarwal Suresh Kumar , Gill Meenu
Published: February 2022

Background: Burns always have posed a threat to the sensitive human body. It is a common catastrophe today as burn injury cases are one of the common emergencies admitted to any hospital. In a medico-legal setting, the main difficulty arises when a burnt body found in unknown circumstances is brought for post-mortem examination. In such a case, a forensic expert has to opine whether the burn injuries sustained are antemortem or post-mortem. It is also of paramount importance to determine the age of burn injuries sustained. Aging of burn injuries by the naked eye is sometimes difficult and unreliable. By histopathological examination of burnt tissue, one can predict whether the victim was alive or dead when the fire was going on and determine the age of burn injuries. Materials and Methods: The present cross-sectional study was carried out in the Department of Forensic Medicine and Toxicology, Pt. B.D.Sharma PGIMS, Rohtak. Total 3033 autopsies were conducted in the mortuary of the Department of Forensic Medicine andToxicology, PGIMS, Rohtak, from November 5, 2011`to November 5, 2013. During that period, out of 486 cases reported burns, randomly 100 cases were selected for this study. Results and Conclusions: In the present study, efforts were made to determine burn wound vitality and age by histopathological evaluation. The study revealed that the inflammatory infiltrate consisted mainly of polymorphonuclear leucocytes in initial stages (up to 3rd-day post-burn) with gradual lymphocytes, macrophages, and fibroblasts forming immature granulation tissue. On the 14th-day post-burn, the burn wound revealed repair by regeneration, increased collagen deposition, fibrosis, and granulation tissue formation. It was infiltrated with fibroblasts, macrophages, and lymphocytes. Our study demonstrated that evaluation of various histopathological changes occurring during the distinctive phases of burn wound healing help in the estimation of its vitality and age.
Profile of Medico legal Autopsies Conducted at Tertiary Medico-legal Centre in Northern India
Authors: Mann Gurmanjit Rai , Saini Rajender Kumar , Saini Nitika
Published: February 2022

The present study is a retrospective study of medico-legal autopsies conducted in the Department of Forensic Medicine and Toxicology MMIMSR Mullana, Ambala, India, from Jan 2016 to December 2020. During this period, 793 cases of medico-legal autopsies were done in the mortuary of MMIMSR, Mullana, Ambala. The majority of victims were male 670 (84.48 %) cases and female 123 (15.52%) cases. A maximum number of post mortem done in the age group 20-40 years was 385(48.56 %) cases and minimum in age group 0-10 year were 18 (02.26%) cases. In our study, 601 (75.78%) were married, 169 (21.31%) unmarried, and unknown 23 (02.99%) cases. Hindus were 660 (83.22%), Muslim 50(06.30%), and Sikh 83 (10.48%) cases. The total number of deaths from rural areas was 406(51.20%) cases, which is slightly higher than urban area 387 (48.80%) cases. Manners of death due to natural causes were 38 (04.97%) cases and unnatural 755 (95.20%) cases. In unnatural, (accidents 551 (69.44%), Suicides 186 (23.44%) and homicides 18 (02.24%) cases). A maximum number of death due to Head injury were 235 (29.64%), shock and hemorrhage 188 (23.70%), poisoning 124 (15.64%), others-skeleton and visceral injuries 81 (10.22%), hanging 44 (05.54%), heart attack 38(04.78%), Drowning 23(02.90%), Electrocution 14 (01.76%), strangulation 13(01.64%), burns 11(1.38%), alcoholic 10(01.26%), septicemia 10(01.26%) and snake bite 2(00.26%)cases. A maximum number of deaths occurring between 0-6 hrs of injury was 395(49.82%) cases, and a minimum number of deaths in 24-48 hrs of injury was 22(02.77%) cases.
Hooch Tragedy in Majha Region of Punjab, India
Authors: Singh Jaspinder P. , Chaudhary Neha , Kumarm Kuldip , Chanana Ashok
Published: February 2022

Due to rampant unemployment, the youth does not hesitate in engaging themselves in any work/job from where they can earn their livelihood. The underground trade of drug trafficking, drug peddling, and drug abuse is prevalent in this part of India for decades. This illicit trade affects the economy of the State and causes the physical, social, and mental degeneration of the persons consuming it. Recently about 150 people were affected after consuming illicit distilled spurious liquor in the Majha region of Punjab, and more than 100 people died due to it. Some of the cases were admitted to the hospital attached to Government Medical College, Amritsar. Out of these admitted cases, few of them succumbed to poisoning whose Forensic autopsies were conducted by the Department of Forensic Medicine and Toxicology, GMC, Amritsar. The meticulous autopsy findings and the scientific interpretation of the analysis of the detected methanol alone or along with ethyl alcohol reported by the chemical examiner to Punjab government led to the establishment of a definite cause of death which helped the investigating agencies in apprehending the people involved in these criminal activities.
A Pre-experimental Study to Assess the Effectiveness of Structured Teaching Programme on Knowledge Regarding Substances Abuse among Boys at Selected Senior Secondary Schools in Jalandhar, Punjab state of India
Authors: Singh Jagwinder , Gupta Rajratan , Andrade Reema J.
Published: February 2022

Background: Substances abuse is dangerous not only for health but also in the view of economic and social values. The habit of substance abuse becomes the cause of purposeless waste of money and affects health. This study was conducted to assess the effectiveness of a structured teaching program on knowledge regarding substances abuse among boys at selected senior secondary schools. Methodology: A pre-experimental pretest-posttest is used. The setting is at senior secondary schools Jalandhar. The sample includes 60 boys selected by a convenient sampling technique. The tool consisted: Part 1 demographic variables and part 2 structured knowledge questionnaire. The reliability of the tool was established by using the split-half method. Results: The study’s findings show that the mean score, median score and SD in the pre-test were 12.78, 12.5 and 2.92, respectively, whereas the mean score, median score, and SD in post-test were 22.58, 23 and 2.02, respectively. The calculated ‘t’ value was found to be 19.2 while the tabulated value of the ‘t’ at 0.05 level of significance is 1.645, which is lesser than the calculated ‘t’ value. It was safely assumed that STP had a definite impact on raising students’ knowledge of substances abuse.
Internship in Forensic Medicine 8 Toxicology-A Proposed Curriculum
Authors: Bhattacharyya Partha   S.
Published: February 2022

The controlling authority for medical education in India has finally taken the much-needed decision to increase the course duration of the subject Forensic Medicine 8 Toxicology (FMT). The subject has been now included in the 3rd Professional MBBS (Part 1), thus increasing the course duration by nearly one year. There is now also a provision for 15 days of elective internship posting in the subject. However, these 15 days of training are often not optimally utilised as there is a lack of clear-cut guidelines. The MCI/NMC curriculum is vague and too much open for interpretation in this regard.1 So a standard curriculum that can easily be followed in all Medical Colleges of India is much necessary to ensure a uniform standard of training.