bluuebunny/crossref_metadata_2025 huggingface dataset:
Relato de caso: Tumor Teratoide rabdoide atípico em criança de 2 anos
Authors: Santos Marina Eduarda , Queiroz Letícia Calazans , Freire Gabriel Henrique de Faria , Lemos Tales Tomé , Rodrigues Rogério Pinheiro , Mattos Vinícius Silva , Mozzer Leandro Regis
Published: August 2022

O tumor teratoide rabdoide é uma neoplasia primária rara do sistema nervoso central (SNC) que tem maior prevalência em crianças menores de três anos. Tem evolução peculiar com tempo de sobrevida muito curto principalmente nas faixas etárias inferiores a três anos. Relatamos um caso de criança de dois anos, sexo feminino, com tumor em região supra-selar e região frontal, principalmente à direita, queixas de cefaleias intensas e persistentes, progressivas, associadas a vômitos e refratárias a analgésicos comuns. A ressonância magnética (RM) de crânio evidenciou lesão expansiva compatível com tumor de SNC. Paciente foi operada, o diagnóstico foi estabelecido por análise histopatológica e a imuno-histoquímica revelou tratar-se de tumor teratoide rabdoide atípico (TTRA). Paciente passou, ainda, por reabordagem cirúrgica devido a recidiva tumoral e, posteriormente, foi realizada radioterapia. Evoluiu para o óbito seis meses após o diagnóstico de TTRA. O tratamento desse tipo de tumor representa um grande desafio na oncopediatria; há muitas abordagens descritas, mas nenhum consenso em relação ao melhor método. Não se observa, até o presente, a superioridade de um esquema terapêutico sobre outro, não havendo aumento significativo da sobrevida ou cura do paciente.
Ectopia Lentis Et Pupilae
Authors: Melo e Silva Eduardo Mariano de Oliveira , Clark Juliana Gonzaga de Araujo , Góes Lucas Brandão Damasceno , Pereira Anna Flávia Ribeiro , Cordeiro Frederico de Miranda
Published: August 2022

Introdução: A ectopia lentis et pupillae é uma condição autossômica recessiva que se refere a um deslocamento do cristalino da sua posição normal, associado a uma má formação pupilar, podendo ser hereditária ou adquirida. O cristalino pode estar completamente deslocado, deixando o olho afácico, ou parcialmente deslocado/subluxado. Entre as causas, têm-se as as hereditárias como a aniridia, síndrome de Marfan, Homocistinúria e Weill-Marchesani ¹ e as adquiridas como traumas, pseudoexfoliação, inflamatórias e catarata hipermadura. O manejo clínico e cirúrgico desses casos é um desafio para os oftalmologistas. Descrição de caso: Paciente masculino, 45 anos, queixa de baixa acuidade visual em ambos os olhos (AO) de longa data. Nega cirurgias prévias, comorbidades congênitas ou traumas oculares. História familiar de avô e irmão amaurótico, de causa desconhecida. Portador de epilepsia, em uso de fenobarbital e fenitoína. Ao exame, olho direito sem percepção luminosa e olho esquerdo com percepção à luz. Biomicroscopia revelava iridodonese, ausência de midríase medicamentosa e afacia AO. Fundoscopia difícil de realização, aparentemente com presença de espículas ósseas, retina pálida e vasos em fios de prata AO. Ultrassonografia ocular (ECO-B) demonstrou luxação de cristalino para o cavidade vítrea com espessamento de hialóide AO. Discussão: A ectopia lentis et pupillae está relacionada a perda da capacidade de dilatação da pupila que reage pouco aos colírios midriáticos. Além disso, os pacientes podem apresentar baixa acuidade visual, miopia axial grave, descolamento de retina, diâmetro corneano aumentado, catarata e alterações irianas à transiluminação².Conclusão: O diagnóstico dessa condição ainda é difícil devido às limitações na literatura. Entretanto, apesar desses empecilhos, o acompanhamento adequado e a reabilitação desses pacientes se tornam imprescindíveis para maior inserção na sociedade.
The fixed image in cinema as a potential altered vision strategy
Authors: Acquarelli Luca
Published: August 2022

The article intends to propose some analyses of a possible formal occurrence of “altered states” in cinema: the stopping of the flow of the cinematographic image in a still image. Through some theoretical references (Metz, Bazin, Lyotard, Deleuze, Bellour, Barthes, Montani) I will try to understand if this kind of formal occurrence can be constituted as a figure of the altered state. The relationship between cinema and photography will be particularly explored, starting with films such as Antonioni’s Blow Up and Bergman’s Persona. The hallucinatory effect will thus be discovered not as opposed to that of reality, but a dialectic will be constructed between the two.
In vitro Antimicrobial Activity of Secondary Metabolites of an Endophytic Aspergillus brunneoviolaceus Isolated from Bryophyllum pinnatum (Lam.) Oken
Authors: Okonkwo-Uzor Nkechi J. , Okezie Ugochukwu M. , Eze Peter M. , Ikegbune Chidozie , Okoye Festus B.C. , Esimone Charles O.
Published: August 2022

The antimicrobial properties of secondary metabolites produced by the endophytic Aspergillus brunneoviolaceus associated with the Nigerian plant Bryophyllum pinnatum were investigated in this study. Standard procedures were followed for fungal isolation and identification, as well as fermentation and extraction of fungal secondary metabolites. The agar-well diffusion method was used to assess the antimicrobial activity of the fungal extract. At 1 mg/mL, the fungal extract demonstrated broad spectrum antibacterial activity against the test bacteria (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and Bacillus subtilis), with inhibition zone diameters (IZD) ranging from 14 to 16 mm. The extract also exhibited antifungal activity with an IZD of 16 mm produced  against Candida albicans. The findings of this study indicate that endophytic A. brunneoviolaceus associated with B. pinnatum has the potential to be a promising source of novel antimicrobial compounds with pharmaceutical importance.
Bed Linen: A Reservoir Of Antibiotic-Resistant Bacterial Pathogens
Authors: Chidimma Ruth Chukwunwejim , Emelumadu Nmesoma , Ebenebe Ijeoma Ngozi , Egbuna Roselyn Nneka , Ugochukwu Jane Ijeoma , Eze Peter Maduabuchi
Published: August 2022

The burden of community acquired infections in the health care system has continued to receive little or no attention especially among healthy, asymptomatic individuals. The aim of this study is to evaluate the bacterial burden of bed linens of undergraduate students living in a university hostel. Twenty-three (23) cotton-swab samples were collected aseptically from both the posterior and anterior end of the bed linen. Microbial isolates were isolated and characterized using standard microbiological and biochemical methods. The antibiotic susceptibility profile of the isolates was determined using the Kirby-Bauer disk diffusion method. A total of nine (9) bacterial isolates were obtained from the samples, including Staphylococcus aureus (7) and Escherichia coli (2). Antibiotic susceptibility testing revealed that the majority of the isolates were resistant to cefuroxime, nitrofurantoin, ceftazidime, cefixime, erythromycin, and augmentin. All E. coli and  S. aureus strains showed 100% resistance to cefuroxime, ceftazidime and nitrofurantoin. However, both bacterial species were only most susceptible to gentamicin and ofloxacin, with E. coli demonstrating the least resistance (0%) to the two antibiotics. The antibiotic resistance of these isolates necessitates immediate attention.
Antioxidative Stress And Hepatoprotective Activities Of Leaf Extract And Fractions OF Saccharum officinarum in Plasmodium berghei Infected Mice
Authors: Okokon JUDE , EDEM UTIBE , BASSEY AUGUSTINE
Published: August 2022

Saccharum officinarum (Family-Poaceae) is used in Ibibio ethnomedicine for the treatment of various diseases such as malaria. The leaf extract and fractions of S. officinarum were investigated for antioxidative stress and hepatoprotective activities in Plasmodium berghei-infected mice using early infection test model. Antioxidative stress and hepatoprotective potentials were assessed by determining oxidative stress markers levels, liver function indices and histopathology of liver.  The leaf extract (170-510 mg/kg, p.o.)  exerted significant (p<0.05) antimalarial activity against P. berghei infection in suppressive tests with n-hexane and butanol fractions having the highest activity. The leaf extract and fractions also caused significant (p<0.05) increases in the levels of oxidative stress markers enzymes and molecules (CAT, GPx, GST)with no significant (p>0.05) effect on GSH, SOD and MDA levels in the liver of the treated infected mice. The extract/fractions treatment caused  significant (p<0.05) reductions in liver enzymes (ALT, AST and ALP), total and conjugated bilirubin of the treated infected mice. Histology of liver revealed absence or significant reductions in pathological features in the treated infected mice compared to untreated infected mice. These results suggest that the leaf extract/fractions of S. officinarum possess antioxidative stress and hepatoprotective potentials  which gives credence to its use in the  treatment of malaria.
Some generalised extended incomplete beta functions and applications
Authors: YAĞCI Oğuz , ŞAHİN Recep , KIYMAZ İ. Onur , ÇETİNKAYA Ayşegül
Published: August 2022

This paper introduces generalised incomplete beta functions defined by the generalised beta function. Firstly, we provide some of the generalised beta function's basic properties, such as integral representations, summation formulas, Mellin transform, and beta distribution. We then present several fundamental properties, such as integral representations, summation formulas, and recurrence relations with the help of the generalised incomplete beta functions.
KONTRIBUSI TINGKAT KEMISKINAN TERHADAP PENDAPATAN ASLI DAERAH DI KABUPATEN PURBALINGGA
Authors: Priambodo Aji
Published: August 2022

Pada tahun 2020, Kabupaten Purbalingga mempunyai tingkat kemiskinan ke-5 terbesar di Provinsi Jawa Tengah dengan tingkat kemiskinan mencapai 15,90%. Sampai saat ini Pemerintah Daerah Kabupaten Purbalingga berupaya untuk menurunkan tingkat kemiskinan dalam tahun terakhir walaupun sempat mengalami kenaikan tingkat kemiskinan karena Covid-19. Adanya tingkat kemiskinan ini diduga berdampak pada Pendapatan Asli Daerah Kabupaten Purbalingga. Penelitian ini bertujuan untuk menganalisis pengaruh tingkat kemiskinan terhadap Pendapatan Asli Daerah Kabupaten Purbalingga. Penelitian ini menggunakan objek penelitian di Kabupaten Purbalingga, dan merupakan penelitian jenis deskriptif kuantitatif dengan menggunakan data sekunder dari Badan Pusat Statistik (BPS). Dalam jumlah ini jumlah sampel yang digunakan adalah time series dengan rentang kurun waktu 2011-2020. Metode analisis ekonometrika yang digunakan adalah regresi liner. Hasil penelitian menunjukkan bahwa tingkat kemiskinan berdampak sekitar 43,69 % terhadap Pendapatan Asli Daerah Kabupaten Purbalingga.
МИОКАРД ҚАН ТАМЫРЛАРЫ ЭНДОТЕЛИІНЕН VEGF ЖӘНЕ CAVEOLIN-1 МАРКЕРЛЕРІ ЭКСПЕРССИЯЛАНУЫНЫҢ ЛИНДАННЫҢ СОЗЫЛМАЛЫ ӘСЕРІ КЕЗІНДЕГІ ЕРЕКШЕЛІКТЕРІ
Authors: Рахманов Сапаргали Бекжанұлы , Балмагамбетова Ару Дюсенқызы , Жанабаева Айгуль Болатбекқызы , Жумабай Нұрканат Асанұлы
Published: August 2022

Зерттеу мақсаты: Линданның созылмалы әсері кезіндегі миокард қан тамырлары эндотелиінен  Caveolin -1 мен VEGF экспрессиясын миокард аймақтарына сәйкес салыстырып зерттеу.

             Зерттеу әдістері мен материалдары: Тәжірибелік зерттеуге салмағы 16-20 г. болатын 40 ақ тексіз тышқандар алынды. Бұл зерттеу бұған дейінгі жүргізілген (бірінші зерттеу жұмысы) тәжірибелік жұмыста қолданылған зертханалық жануарлардың ұрпақтары. Тәжірибелік жануарлар 2 топқа бөлінді: 1 топ- хлорорганикалық пестицид Линданның әсері, 2 топ – бақылау. Линданды per os енгізілді және зерттеудің 2-ші айының соңында жануарлар декапитация әдісімен эксперименттен шығарылды. Эксперимент соңында иммунофлюоресцентті микроскоптың көмегімен алынған жүрек препараты иммуногистохимиялық әдісті қолдана отырып, кавеолин - 1 (Cav-1) және VEGF зерттелді. Алынған мәліметтерді статистикалық өңдеу жүргізілді.

             Зерттеу нәтижелері және талқылау: Зерттеу тобында миокардтың эндокардқа жақын аймағында эндотелийдегі кавеолин тұтастығы барынша сақталғанымен, олардың тізбекті орналасуы өзгерген, жарықтану алаңы айқын, тек кейбір жерлерде үзілген аймақтарды байқауға болады. Cav-1 экспрессиялайтын жасушалар көру алаңында 77,3±1,003 % құрап, бақылау тобымен салыстырғанда 12,3% жуық азайған (р<0,05). Миокардтың эпикардқа жақын аймақтарында Cav-1-ге оң мәнді жасушалар көру алаңында 71,6±1,2% құрап, бақылау тобымен салыстырғанда 9,5 % жуық азайған. VEGF-тің экспрессиялану ерекшеліктері бойынша, миокардтың эндокардқа жақын аймақтарындағы қан тамырлар эндотелиінен VEGF маркерінің экспрессиялануы 27,3±0,2 % құрап, бақылау тобынан 3 % жуық қана артқан. Бұл көрсеткіш миокардтың эпикардқа жақын аймағындағы көрсеткіштермен салыстырғанда айқын өзгерістер анықталған жоқ, VEGF-ке оң мәнді жасушалар 25,8±1,03 % құрады. VEGF маркерінің экспрессиялану ерекшелігі, бақылау тобымен салыстырғанда 1 – 3 % аралығында артқан (р<0,05), яғни айқын өзгеріс жоқ. Яғни, линданның созылмалы әсері ангиогенезді белсендіретіні анықталды.

             Қорытынды. Тәжірибелік жануарлардың ұрпақтарында линданның созылмалы әсері өзіндік ерекшелігімен көрініс берді. Линданның эндотелий тұтастығының маңызды факторы Cav-1 белсенділігінің төмендеуіне әсер ететіні анықталды. Сонымен қатар, миокард ангиогенезі белсенділігінің артуы VEGF экспрессиясының артуы анықталды.
МОРФОЛОГИЧЕСКИЕ, ГИСТОХИМИЧЕСКИЕ ИЗМЕНЕНИЯ И М	ОНООКСИГЕНАЗНАЯ СИСТЕМА ПЕЧЕНИ ПРИ ВОЗДЕЙСТВИИ ИНДОЛА В ЭКСПЕРИМЕНТЕ
Authors: Даминов Акмал Охунжонович , Халиков Пулат Хужамкулович , Курбанов Абдубурхон Кузибаевич
Published: August 2022

Цель: изучение морфологических, гистохимических изменений и состояния монооксигеназной системы печени при однократном, остром и хроническим воздействии индола в эксперименте.

             Материал и методы. В работе в качестве подопытных животных использовали беспородных белых мышей. Все животные находились в стационарных условиях вивария. Индол, растворённый в оливковом масле, вводился внутрижелудочно с помощью шприца и иглы с закругленным концом.

             Результаты и обсуждение. В серии экспериментов был определён уровень содержания индола в крови путём введения различных доз препарата. Гистохимическими методами выявлялись: РНК по Браше, гликоген – ШИК-реакцией по Мак Манусу, Хочкиссу. Электронно-микроскопические исследования проводились по общепринятой методике. Ультратонкие срезы исследовалисьи фотографировалисьна электронном микроскопе Hitachi Н-600. При описании гистологических препаратов и электронограмм использовалась Международная гистологическая номенклатура.

             Заключение. Экспериментально установлены токсические эффекты индола, как при однократном, так и при многократном воздействии, а также обнаружены патоморфологические изменения в печени. Определены особенности временных проявлений и степени выраженности патоморфологических измененийв зависимости от дозировок и периодичности воздействия индолом, сделаны соответствующие выводы.
ASSESSMENT OF MORPHOLOGICAL CHANGES IN THE THYROID GLAND BY TEST-POINT METHOD WITH THE INTRODUCTION OF DIPSACOSIDE
Authors: Дон Андрей Николаевич , Нагай Савелий Григорьевич , Садикова Диёра Зафаровна
Published: August 2022

The search for herbal medicines for the treatment and prevention of atherosclerosis remains the most important problem of modern medicine. Dipsacoside is one of these drugs, it is the sum of triterpene glycosides, obtained in the laboratory of pharmacognosy of the Institute of Biopharmacology of the Academy of Sciences of Kyrgyzstan M.M. Mukhamedziev (head of the laboratory - Ph.D. P.K. Alimbaeva). The results of the experimental study showed changes in structural parameters indicating an increasing morphological and functional activity of the thyroid gland under the influence of daily oral administration of an aqueous solution of dipsakozide at a dose of 10 mg/kg of animal weight.
АНАТОМИЯНЫ ОҚЫТУДАҒЫ ИННОВАЦИЯЛЫҚ ТЕХНОЛОГИЯЛАР
Authors: Хамидулин Болат Сагдатович , Алмабаева Айгуль Ыдырысовна , Tazhimetov Bekzat , Жаналиева Марина Кубеновна , Шаяхметов Дулат Арманович , Минайдаров Азамат Кадырханович
Published: August 2022

Полимерді бальзамдау технологиясын оқу процесіне кеңінен енгізу дәстүрлі формалинмен бекітілген препараттарға қарағанда тиімді және бірқатар артықшылықтарға ие
ВНУТРИОРГАННЫЕ И ВНЕОРГАННЫЕ ЛИМФАТИЧЕСКИЕ СОСУДЫ СЕРДЦА
Authors: Сатыбалдиев Масалбек Абдылдаевич , Абаева Тамара Сурналиевна , Эргешова Аида Масалбековна , Жанганаева Мира Тобокеловна , Абирова Рахат Эсеналиевна , Тамаева Кукун Аширбековна
Published: August 2022

Цель нашей работы является изучение строения внутриорганные и внеорганные лимфатические сосуды сердца.Материалы и методы. Изучены строения внутриорганные и внеорганные лимфатические сосуды сердца. Изучены от 18 трупов людей обоих полов. Инъекционной методикой выявлены лимфатические капилляры, сосуды левого и правого желудочков, а также предсердий.Результаты и обсуждение. Во внеорганных лимфангионах количество миоцитов в мышечной манжетке всегда больше, чем в стеке клапанного синуса. Миоциты находятся в тесных взаимоотношениях с коллагеновыми и эластическими волкнами.Заключение. Следовательно, калибр лимфангионов интраорганного и экстраорганного сосуда варьируется в широких пределах. Уменьшается количество миоцитов в стенке лимфангионов интраорганного сосуда
УЛЬТРАСТРУКТУРА СЛИЗИСТОЙ ТОЛСТОЙ КИШКИ У БОЛЬНЫХ ОСТРОЙ ДИЗЕНТЕРИЕЙ
Authors: Одилова Гулноза Махсудовна , Шайкулов Хамза Шодиевич , Хусанов Эркин Уктамович
Published: August 2022

Сущность поражения кишечника при дизентерии стала ясной благодаря применению современных методических приемов морфологического исследования, таких как люминесцентная микроскопия, окрашивание микробов на обычных гистологических срезах, изучение ультра структурных аспектов взаимодействия слизистой кишечника с шигеллами.Цель настоящего исследования — изучение ультраструктуры слизистой толстой кишки больных острой дизентерией в разных стадиях и формах болезни.Материалы и методы. Под наблюдением находилось 146 больных острой дизентерией, у которых брали материал для гистологических и ультраструктурных исследований методом аспирационной биопсии в динамике: в момент поступления больного в стационар, после окончания специфического лечения, в период ранней реконвалесценции, когда клинические -проявления исчезали, и накануне выписки.Результаты и обсуждения. Были выделены 4 группы больных по клиническим формам заболевания: тяжелая, среднетяжелая, легкая и стертая. Преобладали среднетяжелые (56,0%) и легкие формы (26,0); реже встречались тяжелые <6,1) и стертые (12,0%). Диагноз подтвержден бактериологически у 74,0% больных. По этиологическому фактору дизентерия характеризовалась разнообразием возбудителей, среди которых ведущую роль играли шигеллы Флекснера1а (49,0%), Зонне (33,3%), Флекснера2а (12,1%) и Бойда (5,6%).Заключение. Таким образом, проведенные исследования показывают, что в самые ранние сроки острой дизентерии изменениям подвергаются в основном энтероциты поверхностного эпителиального слоя и верхней части крипт. Именно в эти сроки наблюдается внутриэпителиальная локализация микробов. Характерно, что при экспериментальной дизентерии внутриэпителиальное паразитирование шигелл отмечается также в ранние сроки заражения.
МОРФОЛОГИЯ ВИЛОЧКОВОЙ ЖЕЛЕЗЫ ПЛОДОВ И НОВОРОЖДЕННЫХ ДЕТЕЙ ПРИ ОСЛОЖНЕННОЙ БЕРЕМЕННОСТИ С ГЕСТОЗОМ НА ФОНЕ АНЕМИИ БЕРЕМЕННЫХ ЖЕНЩИН
Authors: Адайбаев Толеугали Адайбаевич , Алмабаевна Айгуль Ыдрысовна , Габдуллина Гульнар Сайлауовна , Сулейменова Фатима Машимовна , Жаналиева Марина Кубеновна , Сагимова Гульзира Касымжановна
Published: August 2022

Цель исследования. Изучить динамику морфологических изменений структуры вилочковой железы плодов и новорожденных детей при осложненной беременности с гестозом на фоне анемии беременных женщин.Материалы и методы исследования. Материалом для морфологического исследования явилась вилочковая железа от 50 мертворожденных и умерших новорожденных в перинатальном периоде.Результаты и обсуждение. Проведен анализ морфологических структур вилочковой железы плодов и новорожденных при осложненной беременности с гестозом. Данные свидетельствуют о нарушении процесса формирования структур вилочковой железы во всех возрастных периодах перинатального развития.Заключение. Выявленные морфологические изменения в вилочковой железе, приводят к состоянию иммунодефицита растущего детского организма. Позволяют лучше понять закономерности строения и развития органов иммуногенеза и стандартизировать иммуноморфологические данные в процессе онтогенеза иммунной системы.Полученные морфологические изменения могут быть использованы, для оценки состояния центральных и периферических органов иммуногенеза при экспериментальных исследованиях.
ОПРЕДЕЛЕНИЕ БЕСКАПСУЛЬНОЙ ЛИМФОИДНОЙ ТКАНИ В СЛИЗИСТОЙ ОБОЛОЧКЕ И ПОДСЛИЗИСТОЙ ОСНОВЕ У ПАЦИЕНТОВ С ПИЩЕВОДОМ БАРРЕТТА
Authors: Ажкен Бахтияр Талғатұлы , Апсалямов Валий Хамитович , Макишев Абай Каиргожинович , Барышев Борис Борисович , Григоревский Владимир Петрович , Жагипаров Мурат Кабпасович , Жакипбаев Касым Адилкасымович , Тажикова Айгуль Маратовна , Джантемирова Назгуль Маратовна , Куканова Асия Маратовна , Бекишева Айжан Танирбергеновна
Published: August 2022

Цель: определить наличие бескапсульной лимфоидной ткани в подслизистой основе пищевода Барретта.Материалы и методы. Дата исследования: 05.2021-04.22. Дизайн исследования: описание серии случаев. Объект исследования: были использованы биоптаты пищевода Барретта у 12 больных до и во время лечения для получения гистологических снимков на базе ГКП на ПХВ Многопрофильный медицинский центр акимата города Нур-Султан. Материал фиксировался в нейтральном формалине, толщина среза 7-8 мкм.; Окрашивание: Гематоксилин-Эозин. Гистологические исследования и микрофотографии производились с помощью микроскопа “Leica”. Гистологическое исследование проводилось на кафедре гистологии, цитологии и эмбриологии НАО «МУА». Результаты исследования. В исследуемой группе из 12 пациентов с метапластическим пищеводом Барретта (ПБ) у 10 пациентов получавших лечение (83,3% мужчин, средний возраст на момент обращения 68,5 лет) при гистологическом исследовании была обнаружена слизистая оболочка пищевода Барретта; радиочастотный метод у 2 (20%), эндоскопическая резекция слизистой оболочки желудочно-кишечного тракта у 4 (40%) и оба метода у 4 (40%). Два пациента (16,6%) ранее лечение не получали. У всех 12 пациентов (100%) с ПБ были определены гистологическим методом лимфоидные узелки в подслизистой основе. Заключение. Лимфоидные узелки в подслизистой основе пищевода Барретта были определены во всех изученных образцах во время гистологического исследования. Процесс формирования узелков, опосредованный проникновением через вены с высоким эндотелием, затрагивает клеточные звенья иммунной системы. Все 4 типа лимфоидных скоплений, а также межэпителиальные лимфоциты, по-видимому,включаются в единую систему лимфопоэза. Структура и состав локальной иммунной системы пищевода Барретта, а также их потенциал для регулирования иммунных реакций верхнего отдела желудочно-кишечного тракта во время гомеостаза и воспалительного заболевания пищевода требует дополнительного изучения.
Prevalence of Chronic Venous Disease in primary care centers in Azerbaijan: the VEINSCOPE study
Authors: Aghayev Farhad
Published: August 2022

Aim: CVD is a chronic disorder that substantially changes the quality of life for the patient since the first symptomatic stages. The effect of CVD in the general population is often undervalued and not well detected by health systems. The aim of this study was to update the information on the prevalence of CVD and its stages in accordance with CEAP classification and evaluate the treatment status of CVD patients and the tactics and steps of GPs undertaken in order to manage these patients.
Material and Methods: This cross-sectional multicenter study was performed in primary care centers in which sequential patients searching medical help, regardless of reason, were enrolled. The study included 3249 patients. Data were collected by the use of a questionnaire and clinical examination.
Results: The prevalence of CVD (CEAP categories C0s–C6) was 48.5%. Only 26.9% of the patients had advised with their physicians because of their venous problems in the lower extremities. 30.8% of the patients had received either oral treatment or combination of oral and topical treatments for the given symptoms. Only 5.4% of the cases were redirected to the specialist.
Conclusion: Chronic venous disease is extremely prevalent among patients examined at primary care clinics in Azerbaijan particularly in women and elderly patients. Redirection to a specialist is uncommon.
Concomitant pulmonary embolism and renal infarction associated with COVID-19 infection
Authors: Ulutas Zeynep , Kilic Talat , tekedereli Ibrahim
Published: August 2022

The incidence of thromboembolic events has increased in COVID-19 patients. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is recognized as a provoking factor for acute pulmonary embolism. Concomitant arterial embolism should be kept in mind in cases with pulmonary embolism and COVID-19. Renal infarction should be suspected in a COVID-19 patients presenting with an unexpected symptom such as abdominal pain. In addition, thrombophilia screening should be considered in patients with thrombosis involving multiple organs without the existence of any risk factors.
Clinical Profile of Non-Traumatic Surgical Abdominal Emergencies in a Tertiary Care Centre in Eastern Part of India
Authors: Raj Ayush , Deepmala Deepmala , Kumar Abhay , Pankaj Deepak , Kumar Nitesh , Bhushan Vibhuti
Published: August 2022

Aim: (a) To study the clinical profile, demographics, symptoms, and indicators of patients with abdominal emergencies requiring non-traumatic surgery. (b) To determine the diagnosis and the appropriate treatment options for patients presenting to the emergency room with abdominal surgical crisis that are not trauma related. (c) To examine the results of various treatment approaches in patients who have non-traumatic surgical abdominal emergencies and present to the emergency room.
Methods: The study included all non-trauma patients under 70 years of age who presented to emergency with abdominal pain.
Results: In our analysis, acute appendicitis was the most frequent cause of acute abdomen, followed by acute intestinal blockage, cholecystitis, and nephrolithiasis.
Conclusion: During the workup of these patients, clinicians must take several diagnoses into account; those individuals who may need surgical exploration should be recognised early to reduce their morbidity and death.
Post operative complications of ostomy- A study of 100 cases
Authors: Kumar Meena , Pednekar Jayant , Goyal Dipesh , Khan Nida
Published: August 2022

Stoma creation is not a trivial undertaking. A good stoma can be life saving, but a stoma associated with complications can have a profound impact on the patient’s physical, psychological and social well being. Stomas are created for various indications, such as bowel obstruction, bowel perforation, treatment of anastomotic leak, diverticular disease, rectal injury, inflammatory bowel disease, infections, motility disorders, to name a few. We studied 100 patients with stomas over a period of 4 years to determine the early and late complications associated with them and establish an association with certain patient, pathology and surgical factors that bore an emphasis on the outcome.
The effect of emotional eating on body weight and eating habits in adults
Authors: l Esma , Yilmaz Mustafa , Bodur Mahmut , n Merve , Yardimci Hulya , Keser Alev , Ucar Asli , Ayhan Nurcan , k Ayse , Cakiroglu Funda
Published: August 2022

The aim of this study is to evaluate the effect of emotional nutrition on body weight and eating habits in adults. 2461 volunteers between the ages of 18-and 65 (40.7±13.6 years) participated in this cross-sectional study (M=677, F=1784). Research data were collected with a face-to-face questionnaire. The participants' nutritional habits and status were evaluated with the three-factor eating questionnaire (TFEQ) and a 24-hour dietary recall form. The “International Physical Activity Assessment Questionnaire - Short Form” was used to determine the physical activity level of individuals. Body mass index was calculated by measuring height and body weight. At the end of the study, it was found that 34.5% of the participants were overweight, and 25.1% were obese. The uncontrolled eating and hunger score were significantly higher, whereas it was low in cognitive restraint in individuals who consumed grains as much or more than recommended (p<0.05). And higher cognitive restraint score was found in those who stated that they consumed the milk and dairy products, vegetable and fruit groups as much or more than recommended and the grains less than recommended (p<0.05). In addition, dietary disinhibition (OR=1.142, 95% CI=1.097-1.189), cognitive restriction (OR=1.076, 95% CI=1.050-1.103) and fasting (OR=1.084, 95% CI=1.033-1.137) scores of TEFQ sub-factors been shown to significantly increase the risk of being overweight/obese (p<0.001). These results show that emotional eating has a significant effect on body weight. For this reason, a multidisciplinary approach is required to evaluate the effect of diet therapy and nutrition on the patient and take into account the patient's emotional state, especially in the treatment and control of obesity.
Frailty and depression in the hypertensive older patients; a cross-sectional study
Authors: Yakaryilmaz Funda , Cansel Neslihan
Published: August 2022

Hypertension (HT) is one of the most common chronic diseases in the elderly in our country and worldwide. HT alone can trigger depression and fragility, and it is possible that these three clinical conditions affect each other negatively. However, there is no study in the literature that evaluated the relationship between these variables. In this study, it was aimed to investigate the frequency of frailty and depression in a group of geriatric HT patients, as well as the relationship between these three variables. A total of 276 (mean age:73.0±7.2) HT elderly patients, 126 (mean age:73.6±7.8) of whom were female, were included in the study. All participants were evaluated with the Katz Activities of Daily Living (ADL) index, the Lawton-Brody instrumental activities of daily living (IADL) index, The Geriatric Depression Scale (GDS-15) and the Freid Frailty Index (FFI). Analyzes were performed by dividing them into three groups according to their FFI scores. According to the FFI scores, 94 (34.1%) as pre-frail, 87 (31.5%) as frail and 95 (34.4%) as robust. FFI scores were positively correlated with age and GDS-15. However, FFI scores were negatively correlated with HGS, ADL and IADL. Age (p<0.001, OR= 1.98[1.04-1.16]), ADL (p<0.01, OR= 0.51[0.36-0.71]), IADL (p=0.044, OR= 0.78[0.62-0.99]) and GDS-15 score (p<0.001, OR= 1.24[1.10-1.40]) were found as independent variables for frailty. Our results provide evidence of a consistent bidirectional relationship between frailty and depression in geriatric patients with HT. Additionally, our data show that three out of four people with frailty have depression and one in two people with depression have frailty. Therefore, interventions should be developed to reduce one of the two syndromes in the elderly diagnosed with HT.
Correlation of acromial shape and rotator cuff tears using magnetic resonance imaging
Authors: Petik Bulent
Published: August 2022

We investigated the relationship between four acromial shapes by magnetic resonance imaging (MRI), and the characteristics and occurrence of rotator cuff tears (RCTs). This retrospective study included 621 patients aged 18-90 years who underwent shoulder imaging in the Turgut Ozal University, Training and Research Hospital, Department of Radiology from April 2022 to May 2022. The study reviewed a total of 621 patients, including 377 (60.7%) female, and 244 (39.3%) male patients. Of the total 621 MRI imagines of the patients, 344 (55.4%) were MRIs of the right shoulder, and 277 (44.6%) were MRIs of the left shoulder. No tears were detected in 20.7% of them, and various grades of tears were detected in 79.3% of them. Of the total, 43% had the full thickness and complete tears, and 36.3% had partial tears. A correlation was found between the RCTs and females (p<0.001). No statistically significant relationship was found for left or right shoulder (p<0.065) and acromion type and tear (p=0.465). A correlation was found between the mean acromio-humeral distance of acromion type I, II, and III (mean of three acromion types) and type IV (p<0.001). There were statistical differences between impingement and acromion hypertrophy (ACH) (p<0.001), between tear and impingement (p<0.001), and between tear and ACH (p<0.001). There was no relationship between acromial shape and gender. However, from the point of view of acromial shape, supraspinatus injury and gender were significantly related, namely; right-sided partial tear injuries are more common in females ≥50 years of age with type II acromion shape than with other RCTs.
Use of the SGLT2 inhibitor canagliflozin for control of refractory equine hyperinsulinemia and laminitis
Authors: Kellon Eleanor , Gustafson Kathleen
Published: August 2022

Ten laminitic horses with hyperinsulinemia refractory to diet control, metformin, levothyroxine and pergolide (if diagnosed with PPID) were treated with the sodium-glucose cotransporter-2 inhibitor canagliflozin (Invokana®). Nine horses were hyperglycemic (>5.5 mmol/L) or had a history of hyperglycemia. Prior to instituting therapy, renal function was assessed by determining serum creatinine and blood urea nitrogen concentrations. Canagliflozin was administered orally once a day, with food. Dipstick urinalysis was performed every 2 wk to confirm glucosuria and screen for proteinuria. Owners were also instructed regarding clinical signs consistent with urinary tract infection. All horses responded with a substantial decrease in serum insulin concentrations to normal or near normal values. Laminitis pain resolved in all cases, with regression of fat deposits. Owner satisfaction with outcomes was 100%.
Double-Balloon-Assisted Coiling for Wide-Necked Posterior Communicating Artery Aneurysms with a Fetal-Type Variant of the Posterior Cerebral Artery: A Case Series
Authors: Nariai Yasuhiko , Takigawa Tomoji , Hyodo Akio , Suzuki Kensuke
Published: August 2022

Endovascular treatment for wide-necked posterior communicating artery (PcomA) aneurysms with a fetal-type variant of the posterior cerebral artery (PCA) is often challenging. Since the complete occlusion rates achieved with the currently available treatment methods are unsatisfactory, we aimed to study the effectiveness of a double-balloon-assisted technique for these aneurysms. From September 2014 to August 2020, 6 consecutive patients with PcomA aneurysms with fetal-type PCAs and no previous treatment were treated with this technique at our institution (3 ruptured cases and 3 unruptured cases). The indication for this technique is that the neck of the aneurysm should significantly and broadly incorporate both the internal carotid artery and fetal-type PCA, such that a single-balloon remodeling and single stent would be inadequate to protect both the arteries. In all patients, the fetal-type PCAs were preserved without a stent and with adequate occlusion status. This double-balloon technique can be effective in the treatment of these aneurysms.
Statistical analysis on correlation between unemployment rate and mortality
Authors: Fan Chuwen , Hu Weiyuan , Shu Haiyong
Published: August 2022

Unemployment is a necessary part of social problems. COVID-19 drives unemployment rates around the world to levels unseen in a generation. In this research paper, a secondary statistical analysis of the correlation between the unemployment rate and mortality is made on the data from the National Bureau of Statistics and Local Bureau Of Statistics. (from 2009 to 2019). We collect the unemployment rate and mortality rate for each province in China from 2009 to 2019, along with the data related to GDP. The results show that there is a positive linear correlation between the unemployment rate and the mortality rate in the overall scope.
The slavery under British and the VOC: The Chain of the Revolt
Authors: Chen Tonghao
Published: August 2022

Slavery plays an important role in studying the history of Cape Town and South Africa. The beginning and the development of slavery were naturally accompanied by the slave uprisings. The history of Cape Colony has seen two major ruling governments, the Dutch East India Company (VOC) and the British Empire. There was no organized resistance that occurred in Cape Town during the VOC period. However, a series of slave improvements by the British government led to the outbreak of the revolt. In contrast to the harsh laws of the VOC period, the British kindness to the slaves freed them from their shackles and led to the outbreak of the revolt. The British policy to improve slavery seems to have changed the psychology of slaves, accelerated their desire for the abolition of slavery, and led to the occurrence of revolt. This seems “Unthinkable” to the British government. Although the slave revolts that happened in Cape town are valuable for studying the history of slavery, scholars and the public have overlooked this part of history. This essay aimed to analyze the Behavior of slaves to understand and encourage people to analyze historical events and figures through psychology.
Exploring the inner logic of patriotic education for youth in the new era
Authors: Zeng Xiaohe
Published: August 2022

Patriotic education is a long-standing ideological and political education work carried out by the Party and the State, and its generative logic is mainly divided into three perspectives: historical origin, theoretical source and practical basis. As socialism with Chinese characteristics is facing a new stage of development and the general environment at home and abroad is intricate and complex, it is important to explore the internal logic of patriotic education for youth in the new era in order to enhance the patriotic sentiment and national identity of the majority of youth.
Individual Salvation under the Bushido of Modern Japanese Militarism
Authors: Cheng Mengle
Published: August 2022

In The Diary of Azuma Shiro, we can clearly see the process of a modern Japanese’s individual consciousness being squeezed under the Bushido of fierce nationalism and militarism, and the individual finally fall into salvation. Militarism Bushido provided a cultural and moral basis for the salvation of modern Japanese. In addition, Japanese national character, cultural pattern, and nationalism also provide a basis for the process of individual salvation.
A Comparative Study of the Escape Motif in The Red Badge of Courage and A Farewell to Arms
Authors: Wang Mengni
Published: August 2022

Stephen Crane and Ernest Hemingway expose the survival dilemma faced by the ordinary people, through focusing on real experiences and feelings of the ordinary. With the same setting of war, the plot of escape in both novels reveals not only human instincts to get rid of disasters, but also humans’ psychological changes. The essay analyses reasons and results of protagonists’ escape, followed by social meanings of authors’ description of escapism. Regarding reasons for escape, two Henrys both experience the disillusionment of individual dream. As for the two protagonists’ reasons respectively, Fleming’s determination is worn down by the boring camping and hesitation of other soldiers, which lead to his final escape; Frederic’s escape is the accumulation of constant disillusionment, coupled with his desire for survival. Considering the differences in escape results between the two Henrys, for Henry Fleming, escape is more like a process to realize his insufficiency of sense of responsibility, stimulating his steps towards maturity on personality and recognition; While for Frederic Henry, escape is the inevitable result of his final emotional outburst, plunging him into the bitter tribulation where he suffers the pain of losing Catherine forever. The social meanings of escapism can be discussed from three aspects: characters’ resistance to the vicious social reality, cognitive and ideological construction of humans, and people’s desire to seek belonging in society. Exploring the escape motif in The Red Badge of Courage and A Farewell to Arms is important for establishing the relationship and discussing the differences of them.
SWOT Analysis and Development Path of College New Media Matrix in the Era of Media Convergence
Authors: Xiao Yanyao
Published: August 2022

With the development of media convergence, the media at all levels have been reformed, including the college media. Constructing the new media matrix is the main way to build the college official media in the era of convergence media. In addition to broadening the horizon and paying attention to the influence of the overall environment on the college media inside and outside the university, this paper analyzes the Strengths (S), Weaknesses (W), Opportunities (O), and Threats (T) of the college new media matrix via the SWOT analysis to put forward relevant constructive suggestions.
Crime Rate Control in the Face of Declining Economic Growth
Authors: Wu Runbing
Published: August 2022

China's economy has been under attack with declining economic growth as the post-COVID-19 ushered in. In addition, there is a complicated relationship between economic growth and the crime rate. We analyze the specific impact of the decline of economic growth in the future on the crime rate from three perspectives of western classical criminology theories: social stratification and mobility theory, social anomie theory, and control theory. We also discuss measures to control the crime rate in the face of the decline of economic growth, mainly including improving the quality of economic development, refining the social security system, and developing education. We wish to supply some references for crime rate control in China.
Research on the Digital Enjoyment Right of the Elderly and Its Legal Guarantee under Smart Pension
Authors: Zhu Xiaoyuan
Published: August 2022

Under the realistic background that the aging and digitalization process are intertwined and influenced each other, the pursuit of integrating into the digital society is the basic interest appeal for the elderly to settle down, realize their self-worth, and gain social recognition in the digital age. In order to realize the legal protection of the digital rights of “digitally vulnerable groups” under the new smart pension mode, it is necessary to establish the guarantee concept of equal protection and inclined protection simultaneously by proving the digital enjoyment rights of the elderly. The present study aims to provide constructive ideas for the legal protection of the rights and interests of the elderly in the digital age.
Study on Culture-Loaded Words in Yang Xianyi and Gladys Yang’s English Translation of Roadside Hut of the Old Drunkard from Hermeneutic Perspective
Authors: Zhang Junyu
Published: August 2022

As one of the important cultural carriers, culture-loaded words are always one of the focus of translation research. Chinese abounds in words and phrases with rich cultural connotations. In order to explore culture-loaded words more deeply, this paper, under the guidance of George Steiner’s four translation motion theory (FTMT), takes the perspective of hermeneutics and conducts a study on the culture-loaded words in the English version of Roadside Hut of the Old Drunkard translated by Yang Xianyi and Gladys Yang. Through a theoretical analysis of the work, it is found that the English version of Roadside Hut of the Old Drunkard translated by Yang Xianyi and Gladys Yang is a comprehensive and vivid completion of the four steps of translation: trust, aggression, incorporation and restitution.
Analysis of the Policymaking Process of Undergraduate Tutorial System in China from the Perspective of Multiple Streams Theory
Authors: He Mingyang
Published: August 2022

The formulation process of China's undergraduate tutor system involves many factors. Based on the perspective of multiple streams theory, this paper analyzes and discusses the driving factors for the establishment of China's undergraduate tutorial system policy agenda. Policy makers form the problem stream through surveys of students and teachers; the government and colleges, as policy entrepreneurs, shape the policy stream; under the China’s unique conditions, the educational philosophy of the Communist Party of China and the popularization of higher education develops into the politics stream. At a critical point, the three streams are coupled and the policy window opens, which eventually leads to the introduction of the undergraduate tutorial system. Additionally, this paper also analyzes the defects of the multiple stream’s theory, and puts forward suggestions for the revision of the theoretical model.
Research on the educational Optimization Countermeasures for college students to identify with Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era
Authors: Wang Shuai
Published: August 2022

Strengthen college students’ identify with Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era, it is the realistic requirement of consolidating the security in the field of ideology in China under the current situation, the internal demand of the iterative upgrading of Ideological and political education, and the inevitable pursuit of the all-round development and growth of contemporary college students. Colleges and universities need to deepen the construction of flipped classroom of Ideological and political theory in the cognitive stage, Strengthen the construction of the main front of Ideological and political education in the acceptance stage and the construction of three-dimensional experience mode in the implementation stage. Comprehensively improve the effectiveness of College Students' identify with Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era.
Study the Credibility of Charitable Organizations in China Based on the Third-party Evaluation
Authors: Wang Jing
Published: August 2022

Charitable organizations play an important role in social development, but many charity scandals have occurred in recent years. Resulting in public mistrust of charitable organizations and the charity industry as a whole. Based on the perspective of third-party evaluation, this paper analyzes the problems of charitable organizations in China in terms of access mechanism, internal management, and public participation. It also analyzes in detail the shortcomings of charitable organizations in supervision and evaluation. And put forward countermeasures, especially given the lack of supervision of charitable organizations in our country, make full use of third-party evaluation and mass media to improve the supervision of charitable organizations.
The Legal Protection of the Rights of Digitally Vulnerable Groups
Authors: Chen Zhe , Han Meng’en
Published: August 2022

The profound advance of digital technology has brought us unprecedented dividends. Nevertheless, numerous individuals have become digitally vulnerable due to obstacles to accessing and using digital information, and the citizens' fundamental rights and the order of social life have suffered significantly because of this substantive inequality. Therefore, this paper aims to promote the legal protection of the rights of digitally disadvantaged groups by establishing the concept of digital human rights, empowering rights, and constructing a three-stage guarantee system from the perspective of emerging rights.
Analysis of the Need for Responsibility for Selection Based on Liberalism and Determinism
Authors: Fang Ruofei
Published: August 2022

In reality, people's responsibility is deterministically increased. To better deal with responsibility, this article critically analyzes modern liberalism from the perspective of classical liberalism. This article finds that as long as science serves politics, the responsibility of the individual is infinitely heavy. As a result, people's responsibilities should be lightened, and science should be properly separated from politics. This discovery renews thinking about modern liberalism and determinism.