bluuebunny/crossref_metadata_2025 huggingface dataset:
Operacionalização da política de governança na Administração Pública federal
Authors: Girardi Jeferson , Torres Ricardo
Published: November 2024

Este estudo versa sobre as características da governança pública no intuito de definir o fenômeno e como a Administração Pública federal brasileira o concebe a partir da implementação da política de governança pública de 2017. A abordagem metodológica adotada foi a qualitativa, descritiva, de natureza aplicada, delineada em um estudo de caso em três organizações da administração pública federal: o Ministério da Educação, o Ministério da Indústria, Comércio Exterior e Serviços e o Instituto Nacional do Seguro Social. Como resultados destacam-se a exposição dos conceitos da governança pública, seus princípios, diretrizes e componentes; evidencia-se a ênfase que organizações públicas da pesquisa dão à estrutura tecno-burocrática; realça-se o mérito que o componente da governança como capacidade de governo possui no debate; e finalmente apresentam-se as estruturas e formas que as organizações-alvo do estudo implementam com a política de governança, traduzindo a concepção de governança pública adotada pelo aparelho do Estado.
Uma breve análise de estudos sobre violência contra mulheres no Brasil publicados na ANPOCS entre 2018 e 2022
Authors: Piunti Juliana Cristina Perlotti , Mendes Bembem Júlio
Published: November 2024

Este artigo tem como objetivo levantar e sistematizar estudos que tratam da análise das múltiplas formas de violência enfrentadas por mulheres no Brasil contemporâneo, na perspectiva das Ciências Sociais. Realizou-se, para tanto, um levantamento bibliográfico exploratório das publicações resultantes dos encontros entre 2018 e 2022 da Associação Nacional de Pós-Graduação e Pesquisa em Ciências Sociais (ANPOCS). Este levantamento permitiu identificar os temas relacionados à violência contra mulheres no Brasil e aproximar-nos das diferentes abordagens das Ciências Sociais na interpretação deste fenômeno na contemporaneidade. Entre 2018 e 2022 foram publicados 2797 trabalhos, distribuídos nos diferentes Grupos de Trabalho (GTs). Por meio da ferramenta de busca avançada do site, e da seleção de descritores, foram encontrados nos anais dos encontros anuais 44 trabalhos que abordaram o tema da violência contra mulheres. Estes distribuem-se em diferentes interpretações em termos de referencial teórico e metodológico, com predomínio de autoras mulheres. Os índices de feminicídio apresentados nas publicações alertam para a maior vitimização de mulheres negras. Dada a relevância e urgência de se pensar e promover políticas públicas para o enfrentamento da violência de gênero, considerando as relações entre raça, classe e gênero, aponta-se a necessidade de ampliação do debate sobre o tema e reafirmação deste problema social como uma questão a ser enfrentada política e pedagogicamente em todas as instituições, por homens e mulheres.
Hospitalidade japonesa omotenashi
Authors: Yokoyama Marcos Hideyuki , Santos Maria Victória Pinheiro
Published: November 2024

A hospitalidade pode ser definida como o ato humano de recepcionar, hospedar, alimentar e entreter pessoas. Desde as olimpíadas de Tóquio de 2020, a hospitalidade japonesa tem ganhado visibilidade por meio do Omotenashi - um traço distintivo da cultura japonesa que é essencialmente diferente da hospitalidade ocidental. O Japão tem surfado nos últimos anos em uma onda de otimismo crescente em relação ao turismo receptivo, com quebras de recordes anuais de visitantes, balança de pagamentos positiva e o país entrando cada vez mais em evidência no cenário turístico global. Neste contexto, o presente projeto buscou conceituar a hospitalidade japonesa Omotenashi por meio de uma revisão bibliográfica e análise conteúdo, agrupando os resultados em quatro categorias: econômica, cultural, histórica e geográfica. Como resultado, observou-se que o conceito de Omotenashi está presente naturalmente na sociedade japonesa e tem sido ofertado com um apelo de super serviço caracterizado por qualidade, reconhecimento e atendimento das expectativas dos clientes e serviços sob medida.
projeto Clube do Empreendedor
Authors: Palles Camila Molina , Moellmann Artur Henrique , Siqueira Marília Aparecida dos Santos , Marques Clarice Ramalho , Leite Bruno Nascimento
Published: November 2024

Desenvolver os talentos individuais orientados ao empreendedorismo é uma missão com a qual a educação empreendedora pode contribuir, sendo uma das vertentes possíveis para a inserção dos estudantes nos mundos produtivo e profissional. Conjugar a experiência vivenciada com as teorias desenvolvidas em sala de aula pode estimular o discente a desempenhar, com criatividade e autonomia, o seu papel empreendedor na sociedade. Desta forma, este projeto de extensão tem como objetivo contribuir com o desenvolvimento da educação empreendedora no IFSP Campus Jacareí, a partir de um desafio de apresentações de ideias de negócio pelos estudantes. O desafio consiste na elaboração de uma ideia de negócio no ambiente em que estes estudantes estão inseridos, que deverá ser apresentada a uma banca avaliadora, cujo propósito será analisar e escolher a ideia mais bem estruturada. Espera-se que o projeto sensibilize a comunidade acadêmica do IFSP sobre a importância da geração de ideias de negócio como fator garantidor de uma educação tecnológica sustentada, bem como espera-se que os estudantes consigam visualizar a opção pelo empreendedorismo como uma das vias de inserção nos mercados de trabalho e de serviços, fomentando a ideia de como começar um negócio, desta forma também contribuindo para o desenvolvimento regional.
From Data Analysis to Creative Arts: The Ubiquity and Impact of Artificial Intelligence in Academia
Authors: Lainjo Bongs
Published: November 2024

Integrating Artificial Intelligence in academia has revolutionized various fields with new opportunities for innovation, research, and learning.  The capability of AI to analyze enormous amounts of data at such incredibly short times contributes to research advancement across natural sciences, humanities, social sciences, engineering, and healthcare sciences. For instance, in natural sciences, AI algorithms support various types of data analysis and simulation, helping to make new discoveries and provide methods and new approaches to look at existing research methods. AI advances in social sciences employ prediction modeling and machine learning to enhance economic models and other behavioral analyses. AI has presented humanities advancements in text analysis and interpretation of history work, augmenting the research based on historical data with data analysis. In engineering and technology, AI's role is twofold: enhancing physical security and, at the same time, posing new threats in the form of complex cyber threats. In a related context, AI’s application for diagnosis and treatment planning has been observed in the healthcare sector. It has shown the potential capability of improving the care of patients far beyond any imagined capabilities. Nevertheless, the application of AI in academia comes with some challenges. Privacy, protection, ethical views, and prejudice enhancement are some of the most significant issues that should be considered.  Despite these challenges, AI creates multi-professional collaboration and advances in knowledge and performance in various scientific disciplines. AI continues to thrive in the future of academia, as future advancement holds possible new research horizons, educational improvement, and world problem-solving. With the rapid evolution of AI, its incorporation into academia and its abuses, biases, and risks need to be constantly reviewed
The Impact of Artificial Intelligence on Investment Strategies and Financial Governance in the Tourism and Hospitality Industry
Authors: Ullah Muhammad Faheem
Published: November 2024

This paper focused on the effect of artificial intelligence (AI) on investment and financial management from the year 2010-2024 tourism and hospitality industry. In this context, based on the analysis of quantitative industry data and qualitative case studies, this research explained how the application of artificial intelligence in the field of predictive analytics changed the possibilities of investment decision making and risk controlling. The current research also aimed at finding out how AI can facilitate the improvement of financial governance in terms of processing, monitoring and compliance processes. Studies affirmed that AI implementation resulted to enhanced forecasting precision, operations and financial outcomes for the firms in the sector. However, several limitations such as data privacy, algorithmic bias, and integrated legacy system, were also discussed. This research discusses the emerging trends of AI that can be adopted in tourism and hospitality finance and studies the implications of these trends for the stakeholders.
Mosque Architecture: New Concepts of Bengal During the Sultanate Rule
Authors: Alamin Alamin
Published: November 2024

A mosque is acknowledged as the socio-political and religious hub of Islam; it is more than just a place for prayer. The model mosque for subsequent mosques was the first one constructed in Madinah during the time of the Prophet (s.a.w.). It is indisputable that mosques had a significant influence on the evolution of Islamic architecture. Mosques have played a significant part in the development of Muslim civilization and society. In addition to building mosques in the lands they had conquered as a symbol of their remarkable artistic talent and technique, Muslims are still honored for their outstanding contributions to the Muslim community today. The principles of secular architecture lack cosmic spiritual motivation, whereas mosque building of the Muslim era shows its religious character in an obvious and constant manner. What is expressed by it is undoubtedly determined by the structural concept, the materials used, and the practical and aesthetic uses of the piece. Despite the fact that Islam arrived in Bengal in 1204 A.D. with Ikhtiyar uddin Muhammad Bin Bakhtiyar Khalji, it reached the Indian subcontinent in 712 A.D. Thus, the year 1204 A.D. marks a turning point in Bengali history. The goal of this study is to evaluate and develop the mosque’s construction, ornamentation, and material and design choices made throughout Bengal’s sultanate era.
The Influence of Professional Commitment to Work Climate of Public-School Teachers
Authors: Mangarin Rey Avila , Macalde Ariel A.
Published: November 2024

This quantitative non-experimental study explored the significant influence of professional commitment to the work climate of public-school teachers based on Meyer et al. (2002) that understanding the significant influence of professional commitment on the work climate can be anchored in the broader theory of organizational behavior. The commitment is directly linked to a positive work climate, as employees who are more professionally committed tend to exhibit higher levels of job satisfaction, engagement, and collaboration (Allen & Meyer, 1990). Studies have shown that a strong professional commitment fosters a supportive and innovative work climate, as employees are more likely to share knowledge, support colleagues, and contribute to a positive organizational culture (Colquitt et al., 2013). Thus, the relationship between professional commitment and work climate is symbiotic, with each reinforcing the other to create a more conducive environment for productivity and organizational success (Schneider et al., 2005). In this study, it was found out that all the domains of professional commitment, to wit: organizational commitment, service commitment, work commitment, career commitment, job satisfaction, managing the individual within the team, and managing difficult situation, significantly influence the work climate of public-school teachers.
Supercomputer modeling in the problems of bacterial antibiotic resistance
Authors:   Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Moscow, Russia, Tereshkina K.B. , Tereshkin E.V. , Kovalenko V.V. , Krupyanskii Y.F. , Loiko N.G. ,   Federal Research Centre ‘Fundamentals of Biotechnology’ of the Russian Academy of Sciences, Moscow, Russia
Published: November 2024

In this paper, the molecular mechanisms of interaction between the antibiotic ciprofloxacin and the main protein of the stationary phase of bacterial culture development (Dps, DNA-binding protein from starved cells) studied to solve problems of increasing antibiotic resistance. Unfavorable environmental conditions lead to inhibition of bacterial cell division and transfer cells to the states of internal resource conservation. The main task for the survival of bacteria in difficult external conditions is the preservation of DNA. DNA protection under a number of stresses (starvation, oxidative, etc.) is carried out by its condensation by the DNA-binding protein Dps. In the exponential phase, the content of Dps is 60, in the stationary phase ~200 molecules per cell. The paper considers the effect of the antibiotic ciprofloxacin on this protein. The methods of modern molecular modeling were used: docking, umbrella sampling, molecular dynamics. The energy characteristics of antibiotic binding to the protein were found. The spatial distribution of small molecules relative to the protein at 28oC and 55oC was shown. It was found that the antibiotic can migrate into the protein molecules.
Conducting an econometric research based on the properties of composite fuel
Authors:   Osh State University, Osh, Kyrgyzstan, Tazhikbaeva S. T.
Published: November 2024

This article presents an econometric analysis of a regression model to assess the efficiency of producing composite coal-water fuel using the cavitation-plasticization method. The main goal of the study is to create a mathematical model that will identify the relationships between the physical and chemical parameters of the components of the mixture and its operational properties, such as calorific value, viscosity, stability over time and economic efficiency. The results of a pilot study on long-flame coal are applied to an econometric study. The key factors influencing the calorific value of the fuel, such as the content of pyrogenetic liquid and the stability of the mixture during storage, are considered. When conducting an econometric study using a regression model, calorific value, viscosity, average droplet size, fuel stability and mixture composition were taken as the main factors, and during the study, mixture components were taken in different proportions. Based on regression analysis, a direct dependence of the calorific value of the composite fuel on the plasticizer content and an inverse dependence on the level of mixture stratification were revealed. The results of the study make it possible to propose optimal conditions for increasing the stability and efficiency of composite fuel, which is important for the development of environmentally and economically viable energy resources.
Simulation of a low-temperature isomerization plant in an Aspen Hysys environment and analysis of the model operation
Authors:   Kazan National Research Technological University,  Kazan, Rep. Tatarstan, Russia, Gaifullin D.S. , Garifullina E.V. , Bashkirtseva N.Yu.
Published: November 2024

The article proposes a scheme for modeling the process of low-temperature catalytic isomerization. Currently, isomerization of light gasoline fractions is one of the necessary processes for obtaining high-quality gasoline. This is due to the introduction of new environmental regulations that impose restrictions on the content of aromatic compounds. The raw material for its production is a fraction of n.k.-75 ℃, consisting of normal paraffins with a low octane number. During the simulation, the technological scheme of the process is described, the material balance of the installation is obtained. This model allows you to evaluate the technology of this process, which reduces the likelihood of accidents at work and the likelihood of errors during the technological process.
Specifics of automation and control of the process of drying flotation concentrate in a drum drying furnace
Authors:   Navoi State University of Mining and Technologies, Navoi, Uzbekistan, Kulmurodova N.T. , Kovalev I.V. ,   Siberian Federal University, Krasnoyarsk, Russia,   Navoi State University of Mining and Technologies, Navoi, Uzbekistan,   Krasnoyarsk State Agrarian University, Krasnoyarsk, Russia,   Navoi Mining Metallurgical Combinate, Navoi, Uzbekistan, Kulmurodov Z.S. , Kadirov Y.B.
Published: November 2024

Consideration of the features of automation of control of the process of drying of flotation concentrate in a drum drying furnace is relevant in connection with the fact that at present, when processing minerals, dewatering and drying are critically important aspects from the technical and economic points of view. Automation of this type of technological processes is aimed, first of all, at ensuring optimal removal of water (moisture) with minimal energy consumption. In this article, the methods and materials are based on the completed development of a working project for the construction of a pilot plant for filtration, drying and roasting of the product at a mining and metallurgical plant. It should be noted that the system under consideration uses modern technologies and high-performance equipment that fully meets all the necessary functional requirements. In particular, the Siemens SIMATIC S7-300 CPU 315-2 PN/DP controller is used to collect and process information and transmit it through the EDS-518A-SS-SC-T controlled switch to the plant's ASODU system. The characteristics of the controllers, modules and interfaces of the system are given, and the possibility of redundancy in the interface components of the system is noted, which ensures increased reliability of its operation and minimization of potential losses of data or control and feedback signals.
Promising directions of telecommunication networks development using underwater optical communication lines as part of environmental monitoring of the marine aquatic environment
Authors:   Admiral Makarov State University of Maritime and Inland Shipping, St. Petersburg, Russia, Ksenofontov Yu.G.
Published: November 2024

More than 75% of the Earth's surface is covered with water in the form of oceans. The oceans are far from fully understood at the moment, therefore, due to the phenomenal processes taking place in the aquatic environment, it requires further serious research. UWC's underwater wireless communications play a significant role in monitoring marine flora and fauna, water pollution, natural disasters, oil and gas rig exploration, naval tactical operations, and monitoring changes in the aquatic environment. In this regard, the widespread introduction of UWC has become a vital area of study, involving various military and commercial applications. Acoustic, optical and radio frequency wireless equipment are widely used for underwater data transmission today. The so-called IoUT Internet of Underwater Things and the development of next-generation 5G networks have a great impact on the continuous improvement of UWC, as they are aimed at increasing data transfer rates, interfacing with other information networks and improving energy efficiency. The article contains the main proposals and recommendations for the comprehensive application of existing UWC technologies, as well as recommendations for individual areas for creating next-generation wireless networks to monitor the ecological state of the marine environment.
Experience of swarm application of UAVs in the field of autonomous agriculture
Authors:   Krasnoyarsk State Agrarian University, Krasnoyarsk, Russia, Kovalev D.I. ,   National Research University "Tashkent Institute of Irrigation and Agricultural  Mechanization Engineers", Tashkent, Uzbekistan, Tueva E.V. , Pokusaev D.S.
Published: November 2024

The article analyzes the current experience of swarm application of UAVs in the field of autonomous agriculture. Agricultural UAVs are integral components of automation systems developed for autonomous agriculture and are widely used at various stages of operation due to their accuracy, high efficiency, environmental sustainability and ease of operation. Swarm application of UAVs covers four main stages of agricultural production (growing, planting, management and harvesting). It is advisable to analyze the application of a UAV swarm at each of these stages, assessing the experience of implementing advanced technologies of swarm application of UAVs in the field of autonomous agriculture. The experience of application and the level of development of UAV swarm technology in autonomous agriculture allows us to identify ways to improve swarm performance, scalability and the pace of implementation in modern conditions.
Dynamics of the spread of gaming methods in environmental education conducted on a grant basis (using the example of the Presidential Grants Fund)
Authors:   Bashkir State Pedagogical University named after M. Akmulla, Ufa, Russia, Semushkin Lev Aleksandrovich , Belyakov Igor' Aleksandrovich ,   Russian Presidential Academy of National Economy and Public Administration, Moscow, Russia
Published: November 2024

This article describes the study of the current trend in financing environmental projects. The applications of the winners of the Presidential Grants Fund competition in the field of environmental protection are studied as an object, and game methods of education are studied as a subject. The authors hypothesized that gaming technologies tend to become widespread over the period under study. Based on the grants studied in 2020-2024, the dynamics of content was compiled using the ratio calculation method for the subject of game methods for its implementation. Statistical analysis has refuted the research hypothesis. The authors consider the lack of a universal methodology for developing environmental-themed games as the main reason.
Theoretical and practical aspects of China's renewable energy development
Authors:   Peoples’ Friendship University of Russia, Moscow, Russia, Hui Gao
Published: November 2024

This article introduces new kinds of energy, including solar energy, wind energy, biomass energy, geothermal energy, ocean energy, tidal energy, nuclear energy, shale gas, hydrogen energy and so on. China is relatively rich in new energy resources, and in this realistic context, the active development of new energy is of great strategic significance for national energy security and environmental improvement. The evaluated new energy can replace traditional fossil energy, fill the shortage of oil and natural gas resources, increase energy supply, meet energy demand and ensure energy security. Second, the widespread application of new energy helps to change China's current coal, oil and natural gas-dominated energy mix and reduce greenhouse gas emissions and air pollution caused by fossil energy use. Given that new energy is an emerging industry reflecting the national strategy, it is of great significance to the long-term sustainable development of China's economy as well as the dominant position in international industrial competition; China's new energy is an emerging industry that is still in its nascent stage; at the same time, new energy is an important area of international industrial competition and an area of rapid development of industrial technology. These characteristics of new energy development determine the need to choose a strategic path different from other industries.
Personalization of the adaptive learning method of L.A. Rastrigin based on a frequency dictionary using cluster analysis of text corpora
Authors:   Siberian Federal University, Krasnoyarsk, Russia, Polyansky K.V. , Kovalev I.V. ,   Krasoyarsk Science & Technology City Hall, Krasnoyarsk, Russia,   Navoi State University of Mining and Technologies, Navoi, Uzbekistan,   Krasnoyarsk State Agrarian University, Krasnoyarsk, Russia
Published: November 2024

The application of the adaptive learning method by L.A. Rastrigin to a frequency multilingual dictionary on system analysis is considered. The disadvantages of this method are revealed, such as the lack of personalization in relation to the student when issuing portions of training information. As a solution, it is proposed to modify the criterion of the quality of training. Its formula includes coefficients of significance obtained from data based on cluster analysis of the training collection of text corpora. For this purpose, TF-IDF weighting of terms from the collection was carried out and a correlation matrix was compiled based on the cosine distances of their vectors. As a result, a new criterion of the quality of training was obtained, taking into account the terminological preferences of the student and based on the significance of terms in the training collection of text corpora. The modified adaptive learning method personalizes the learning process, making it more flexible and modern.
Paederia foetida Ameliorates Diabetic Cardiomyopathy in Rats Models by Suppressing Apoptosis
Authors: Javaid Amrah , Omar Norsuhana , Ahmad Rozaziana , Mat Zin Anani Aila , Che Romli Aminah , Isah Tsamiya Rilwanu
Published: November 2024

Diabetes mellitus is one of the most prevalent global public health issues associated with a higher risk of cardiovascular diseases, contributing to morbidity and mortality. Research has demonstrated that elevated reactive oxygen species (ROS) generation in diabetes can trigger apoptosis, exacerbating diabetic cardiomyopathy (DCM). This study investigates the cardioprotective effects of Paederia foetida in rats’ models of type 2 diabetes induced by a high-fat diet (HFD) and streptozotocin (STZ) treatment. The diabetic model was established in Sprague Dawley rats by intraperitoneal injection of streptozotocin (STZ, 40 mg/kg). Sprague Dawley rats were treated with varied concentrations of standardized extract of P. foetida (50 mg/kg and 100 mg/kg), administered orally once daily for four weeks. Standardized extract from P. foetida has a range of therapeutic potential, including anti-inflammatory, antioxidant, and anti-diabetic properties. The common metabolic disorder indices and myocardial apoptosis were investigated. The findings from this study demonstrated increased expression of Bcl-2 and decreased expression of Bcl-2 Associated X-protein BAX as indicated by IRS scoring in cardiomyocytes, suggesting that P. foetida has a significant protective effect on diabetic cardiomyopathy by decreasing apoptosis. Increased Bcl-2 and decreased BAX levels may be related to regulating oxidative stress and mitochondrial pathways involving myocardial apoptosis. P. foetida extract could be a potential intervention for attenuating cardiomyopathy in diabetes mellitus.
JE LI UMJETNA INTELIGENCIJA IZAZOV ZA ETIKU I EMPATIČNO NOVINARSTVO?
Authors: Primorac Bilaver Ivana , Topić Stipić Davorka , Primorac Marijan
Published: November 2024

Dosadašnja iskustva primjene umjetne inteligencije u novinarstvu pokazala su kako ona nije u mogućnosti samostalno obavljati novinarski posao jer je nakon generiranja novinarskoga sadržaja i informacija potrebna ljudska kontrola kako bi kreirani sadržaj prema etičkim postulatima novinarstva bio relevantan i kvalitetan. Novinarstvo se desetljećima orijentira prema etici, profesionalizmu i profesiji. Svi ti ciljevi slijede jedan imperativ: da se ostvaruju na način dostojan čovjeka i sredstvima dostojnima čovjeka. Stoga se postavlja pitanje: Može li u tome kontekstu umjetna inteligencija biti zadovoljavajući odgovor?
Novinarstvo koje prepoznaje vitalna pitanja i vrijednost osobe jest senzibilno novinarstvo, novinarstvo u kojemu ima mjesta za jedinstvenost i empatiju. Umjetna inteligencija ne može prepoznati originalnost, empatizirati, ne može biti dio javnosti, što novinar uvijek jest. U radu se propituju posljedice svođenja novinarstva samo na tehničku operabilnost i dominaciju umjetne inteligencije. Postavlja se pitanje: Izuzimamo li ga iz ljudske, a time iz etičke i moralne dimenzije te gubimo li empatičnu stranu novinarstva?

Ključne riječi: novinarstvo, umjetna inteligencija, etika, empatija, empatično novinarstvo
The Effect of Mixed Lipid Concentrations and Sucrose on the Size of the Lipid Nanoparticles Containing mRNAs
Authors: Widayat Wahyu , Hardianto Ari , Hidayati Rahma Ayu , Nurainy Neni , Burhanudin Muhammad , Yusuf Muhammad , Subroto Toto
Published: November 2024

The development of messenger RNA (mRNA) vaccines has been transformed using lipid nanoparticles (LNPs) as delivery systems. This study evaluates the impact of lipid mixture molar concentration and the addition of sucrose as a cryoprotectant on the size and stability of LNPs encapsulating mRNA. Using a microfluidic mixing technique, we formulated LNPs with varying lipid concentrations and analyzed their size, size distribution, and encapsulation efficiency through dynamic light scattering and a RiboGreen assay. Results indicated that higher lipid concentrations not only improved encapsulation efficiency but also maintained LNPs within the ideal size range of 80-120 nm, crucial for optimal biodistribution and immune cell uptake. Furthermore, the addition of sucrose significantly stabilized the LNPs against size changes during freeze-thaw cycles, particularly at lower temperatures. This study underscores the importance of optimizing lipid and sucrose concentrations to enhance the stability and functionality of LNPs, providing insights that could enhance the efficacy and storage stability of mRNA vaccines.
HIGHLIGHTS

The variation in molar concentrations of mixed lipids affects the particle size of LNP-mRNA.
Buffer exchange using a membrane filter with centrifugation technique can reduce the size and uniformity of LNP particle distribution.
The addition of sucrose affects the particle size of LNP-mRNA.
The addition of 10 % sucrose as a cryoprotectant can maintain the particle size of LNP-mRNA at 4 and –20 °C.

GRAPHICAL ABSTRACT
EFEKTIVITAS MEDIA LEAFLET TERHADAP PENGETAHUAN PENGGUNAAN ANTIBIOTIK DI KABUPATEN BANGKA
Authors: Lana Sari  , Ratih Puspita Kusumadewi Purba
Published: November 2024

Antibiotics are medications that physicians often prescribe to treat and prevent bacterial infections. Antibiotic resistance may be predisposed by improper antibiotic usage practices. The public’s ignorance about the proper use of antibiotics is the cause of this. The quality of a patient’s health will improve if antibiotics are used judiciously and in accordance with prescribed guidelines. If antibiotics are not used as directed, their efficacy will be diminished and the expense of recovery therapy will rise. To guarantee treatment efficiency and avoid resistance, it is essential to understand and be aware of the patients receiving antibiotics. This research sought to determine the efficacy of leaflet media in Bangka Regency, Bangka Belitung Islands Province, in promoting antibiotic use knowledge. A validity-tested questionnaire from previous research served as the study’s instrument. Quasi-experimental in nature, this kind of study uses a pretest-posttest design involving only one group. It also has a quantitative analytical focus. An unintentional sampling strategy combined with a non-random sampling method was employed in the study to acquire data. 166 people served as the study’s subjects. A questionnaire was used as the measuring tool in the study. It was sent to the participants’ community in two assessments, one month apart, and included leaflet media as an intervention. Analytical tests, both univariate and bivariate, were used to examine the data. The results show that there is a substantial difference in knowledge between the pretest and posttest, and that leaflet media is successful in increasing people’s awareness of antibiotics in Bangka Regency. The P-value is 0.001< 0.05.
Onto-teoloji ve Kavramsal Putperestlik
Authors: Bekalp Bilal
Published: November 2024

Bu çalışma Fransız filozof Luc Marion’nun (1946-), Heidegger’in onto-teoloji kavramından hareketle metafiziğin hem Varlık hem de varolanlar arasındaki ilişkiyi nasıl düşündüğünü ve Tanrı’nın bu düşünceye nasıl dahil edildiğinden hareketle de onto-teolojinin putperestlik içerdiği düşüncesinin haklılığını tartışmaktadır. Marion’a göre her ne kadar felsefe, Tanrı’yı en yüksek ya da mükemmel ve sonsuz varlık olarak ele almış olsa da tam da bu ele alış nedeniyle aslında putperestlik sınırları içine dahil olur. Ona göre bu, Skolastik düşünceden başlamak üzere Heidegger’e kadar süren ve Tanrı’yı metafiziksel bir tasavvur nesnesi olarak gören düşüncenin ortak özelliğidir. Onto-teoloji eleştirisini Hiedegger’den alan Marion, buna rağmen onun da Varlık söz konusu olduğunda putperest bir çizgide kaldığını iddia eder. Varlık, bir varolan aracılığıyla düşünülür ve bu da ontolojik farkı) ifade eder. Marion bu farkın görmezden gelindiğini ifade ederken, Tanrı’nın ölümünün bu durumda bir fırsat yarattığını söyler. Bu da Tanrı’nın onto-teolojik ve putperest eğiliminin ortaya çıkması anlamına gelmektedir. Onto-teoloji eleştirisini Nietzsche ve Heidegger gibi düşünürler üzerinden temellendiren Marion, onto-teolojinin ve putperest eğilimin nedenleri açıklayarak, bundan nasıl kaçınılabileceğine yönelik kendi alternatifini sunmaktadır.
ASSISTÊNCIA DE ENFERMAGEM EM PACIENTES COM DEPRESSÃO PÓS-PARTO
Authors: De Oliveira Ranielly Matia , Santos Sabrina Andrade , Cruz Jessica Reco
Published: November 2024

Postpartum depression is a mental disorder that significantly affects the health and well-being of mothers, also affecting their bond with their babies. This study sought to describe and analyze nursing care for patients with postpartum depression, exploring how emotional support and guidance interventions can contribute to the recovery of these women. Aiming to identify nursing practices that favor the adequate management of the disorder, the research used a qualitative approach, developed through a literature review that covered publications from two thousand and twenty to two thousand and twenty-four. The data sources included the Lilacs, Capes and Scielo databases, using as inclusion criteria articles available in Portuguese and that directly addressed nursing care in the context of postpartum depression. Duplicate studies and those that did not address the topic specifically were excluded. The results indicated that nursing plays a fundamental role in the early detection and monitoring of patients, offering emotional support and guidance that help reduce stigma and promote self-care. Nursing interventions, when performed in an empathetic and informed manner, have proven effective in alleviating symptoms of depression and facilitating mothers’ adaptation to the postpartum period. The relevance of integrated action with other health professionals was also observed, enhancing care and contributing to a more complete recovery of patients. The research highlighted the importance of training nursing professionals to deal with the specificities of postpartum depression, promoting sensitive and evidence-based care.
From Waste to Resource: Assessing the Biosorption Efficiency of Citric Acid-Modified Activated Carbon from Corn (Zea Mays) Husks in Aqueous Copper (II) Ion Solutions
Authors: Gamay Kresley P. , Ongayo Glenn D.
Published: November 2024

The global focus on cost-effective and sustainable adsorbents, specifically activated carbon from corn husk wastes, addresses environmental waste disposal issues. This economical solution efficiently removes heavy metal ions and promotes the use of agricultural biomass residue in wastewater treatment. In this study, unmodified and modified activated carbon produced from corn husk waste was investigated for the removal of Cu (II) ions in an aqueous solution. The activated carbon was modified with citric acid, resulting in citric acid corn husk activated carbon (CA-CHAC). Several batch adsorption experiments were carried out for both adsorbents to examine the influences of various factors, including pH, adsorbent dose, and contact time. Additionally, the adsorption system was fitted to isotherm and kinetic adsorption models to characterize its adsorption behavior. Results from adsorption studies showed that both the unmodified (CHAC) and citric acid-modified activated carbon (CA-CHAC) adsorbents achieve their optimum adsorption for Cu(II) at pH=7, with a dosage of 5 mg, and contact times of 45 minutes for CHAC and 30 minutes for CA-CHAC. The outcomes additionally demonstrated that the fundamental mechanism of both adsorbents is most effectively described by both the Langmuir isotherm model and the pseudo-second-order model, signifying that the adsorption system adheres to chemisorption. Maximum removal of Cu (II) ions using CHAC and CA-CHAC was obtained with 69.52% and 82.22% average removal, respectively. Additionally, the maximum adsorption capacities recorded were 77.58 mg/g for CHAC and 88.10 mg/g for CA-CHAC. The findings of this study indicate that corn husk-activated carbon modified with citric acid (CA-CHAC) has the potential to effectively adsorb Cu (II) ions.
Factors affecting sustainable tourism development in Vietnam
Authors: Dao Thi Thuong
Published: November 2024

With a rapid growth rate, in just a short time, the tourism industry has become a type of industry that attracts a lot of labor, contributes a high proportion to GDP, and has a great influence on the economy. To ensure sustainable tourism development, identifying influencing factors is an urgent matter today. Therefore, this article presents a number of factors affecting sustainable development in tourism activities from a personal research perspective. In Vietnam, tourism has long been of interest to the Government, creating favorable conditions for development, and considering it a key industry compared to other economic sectors of the country. From the important reality of the tourism industry, many localities across the country pay great attention to tourism development with the desire to generate large revenues from this field. However, strong tourism development in localities can lead to many consequences. Therefore, studying the relationship between factors to sustainable tourism development is necessary. The requirement for countries and economies around the world is to conduct research to be able to move towards sustainable tourism development, achieving efficiency in all three aspects: economy, society and resource and environmental protection. Therefore, sustainable tourism development is the right direction for the tourism industry in Vietnam as well as all countries in the world. The study "Factors Affecting Sustainable Tourism Development: Survey in Quang Ninh province" by Bui Thi Quyen, Nguyen Thi Mai Huong and Phuong Huu was published in the International Journal of Early Childhood Special Education Vol. 14, Iss. 1 (2022) to support the planning and development of sustainable tourism to provide high quality services, improve the competitiveness of destinations, and ensure simultaneous development of the environment and society in Quang Ninh. Currently, Vietnam is having many positive economic changes. Agriculture is considered the main economic sector, with the second largest export turnover in the world, but has not yet brought high income to the people; The industrial sector requires a large amount of scientific and technical investment capital and a long payback period; meanwhile, the tourism sector is considered a smokeless industry, does not require too much investment and has a quick return period, and is gradually becoming one of the important economic sectors of Vietnam. From there, propose some solutions to promote sustainable tourism development for localities.
Keywords: Tourism, Sustainable Development.
PERTANGUNGJAWABAN PIDANA TERHADAP PELAKU TINDAK PIDANA PEMBUNUHAN BERENCANA YANG DISERTAI DENGAN PERCOBAAN BUNUH DIRI (Studi Putusan Nomor 102/Pid.B/2022/PN.Kla)
Authors: Anggalana Anggalana , Ainita Okta , HS Kadek dela
Published: November 2024

Pembunuhan berencana adalah membunuh yangdilakukan perencanaan mengenai waktu dengan tujuan memastikan keberhasilan pembunuhan atau untuk menghindari penangkapan adapun Faktor penyebab tindak pidana pembunuhan berencana yang disertai dengan percobaan bunuh diri berdasarkan Putusan Nomor 102/Pid.B/2022/PN. Kla. terdakwa melakukan pembunuhan terhadap korban dikarenakan factor cemburu melihat korban jalan dengan pria lain sehingga terdakwa berniat membunuh korban semenjak 1 Minggu sebulum Tanggal 18 Desember 2021. Penerapan hukum pidana terhadap pelaku tindak pidana pembunuhan berencana yang disertai dengan percobaan bunuh diri berdasarkan Putusan Nomor 102/Pid.B/2022/PN.Kla adalah terdakwa Sosiadi Fariyon als Ion Bin Karnadi oleh terbukti melanggar kentuan dalam Pasal 340 KUHP, karena itu terdakwa di pidana penjara selama 20 (dua puluh) tahun. Pertimbangan Hakim terhadap tindak pidana pembunuhan berencana berdasarkan yang disertai dengan percobaan bunuh diri Putusan Nomor 102/Pid.B/2022/PN.Kla ada beberapa pertimbangan yang pertama adalah Jaksa dapat membuktikan dakwanya, tidak ada alasan pemaaf dan pembenar, terpenuhinya 2 (dua) alat bukti dan keadaan yang memberatkan perbuatan terdakwa meresahkan masyarakat serta meringakan terdakwa sopan , menyesail perbuatanya dan terdakwa belum pernah di hukum.
GOVERNANÇA CLIMÁTICA TRANSNACIONAL E DIREITOS FUNDAMENTAIS: DESAFIOS E ATORES NA MITIGAÇÃO DOS IMPACTOS DAS MUDANÇAS CLIMÁTICAS
Authors: Lima Ricardo Araújo , Santos Ana Ailema Morais dos , Arrais Bruna Zita de Alencar
Published: November 2024

As mudanças climáticas representam um dos principais desafios globais, exacerbados por eventos climáticos extremos causados por ações humanas. Nesse contexto, a transnacionalização das políticas climáticas se manifesta como uma estratégia conjectural para mitigar seus impactos e promover a adaptação às transformações ambientais. É necessário repensar o papel do Estado constitucional em um cenário transnacional, onde novas normatividades estão sendo desenvolvidas. A pesquisa analisa a viabilidade do diálogo transnacional sobre mudanças climáticas, focando na cooperação global entre países, organizações internacionais e atores não estatais. A questão central é como essa transnacionalização pode facilitar um regime de governança que mitigue os impactos climáticos. O objetivo é identificar os principais atores, interesses e estratégias envolvidos, especialmente em relação às inundações no Rio Grande do Sul em 2024. A hipótese sugere que a interdependência econômica e a ação coletiva de atores não estatais são essenciais para a implementação eficaz das políticas climáticas, apesar das barreiras geopolíticas. A urgência em abordar as mudanças climáticas está ligada à preservação ambiental e também à proteção dos direitos humanos fundamentais.
Impacts of Barrier-Island Breaching on Mainland Flooding During Storm Events applied to Moriches, NY
Authors: Jeffries Catherine Renae , Weiss Robert , Irish Jennifer L. , Mandli Kyle
Published: November 2024

Abstract. Barrier islands can protect the mainland from flooding during storms through reduction of storm surge and dissipation of storm generated wave energy. However, the protective capability is reduced when barrier islands breach and a direct hydrodynamic connection between the water bodies on both sides of the barrier island is established. Breaching of barrier islands during large storm events is complicated, involving nonlinear processes that connect water, sediment transport, dune height, and island width among other factors. In order to assess how barrier island breaching impacts flooding on the mainland, we used a statistical approach to analyze the sensitivity of mainland storm-surge to barrier island breaching by randomizing the location, time, and extent of a breach event. We created a framework that allows breaching to develop during the course of a simulation and imposes a breach in an approximation of a Gaussian bell-curve that deepens over time. We show that simulating a storm event and varying the size, location, and number of breaches in the barrier island that mainland storm surge and horizontal inundation is affected by breaching; total inundation has a logarithmic relationship with total breach area which tapers off after the entire island is removed. Breach location is also an important predictor of inundation and bay surge. The insights we've gleaned from this study can help prepare shoreline communities for the differing ways that breaching affects the mainland coastline. Understanding which mainland locations are vulnerable to breaching, planners and coastal engineers can design interventions to reduce the likelihood of a breach occurring in areas adjacent to high flood risk.
What do the arc magmatism trace element patterns and Sr-Nd-Pb isotopic data reflect: Insight from the Urumieh-Dokhtar magmatic arc of Iran
Authors: Ghorbani Mohammad Reza , Akbari Meysam , Graham Ian T. , Benoit Mathieu , Sepidbar Fatemeh
Published: November 2024

Abstract. Mafic volcanic rocks from the Cenozoic Urumieh-Dokhtar Magmatic Arc (UDMA) of Iran, a segment of the Alpine-Himalayan orogenic belt, provide rather restricted ranges of trace element abundances and patterns and Sr-Nd-Pb isotopic signatures that are distinct enough to help characterize the geochemical signatures inherited from their arc system components. The volcanic rocks are classified into three series; the LILE-rich, LILE-poor, and incompatible trace elements-rich series (ITE-rich series; that include samples with OIB-like patterns). The LILE-rich series is derived from a mantle source metasomatized by wet-slab partial melts whereas the LILE-poor series, high in immobile, highly incompatible elements that include La, Ce, is derived from a mantle source metasomatized by dry-slab partial melts. The ITE-rich series bear the signatures of mantle metasomatized by slab partial melts that was induced by and reacted with asthenospheric mantle ascended through a slab window or rupture. Given almost primitive geochemical signatures of the mafic rocks, the Sr-Nd isotopic modeling indicate a mantle wedge:slab melt:sediment melt contribution of 45:27.5:27.5 and 55:09:36 for the LILE-rich and LILE-poor series respectively. The mafic volcanic rocks stretching from mantle array (i.e., NHRL) towards enriched mantle on the Pb-Pb isotopic plots support this finding. High Sr and low Nd isotopic ratios of two mafic volcanic rocks from the LILE-poor series stand in sharp contrast to the other mafic rocks from LILE-poor series that plot near mantle array. Less differentiated signature of these two samples along with their older Nd model ages indicate derivation from older metasomatized mantle segments implying that the source mantle of the UDMA is heterogeneous. Eocene to Early Miocene ages for these three series favor intermittent volcanisms of the three rock series over an extended period of time rather than single episodic magmatism for each geochemically distinct magma series.
Intensity and dynamics of extreme cold spells of the 21st century in France from CMIP6 data
Authors: Cadiou Camille , Yiou Pascal
Published: November 2024

Abstract. Cold extremes significantly impact society, causing excess mortality, strain on healthcare systems, and increased demand on the energy system. With global warming, these extremes are expected to decrease, as observed in various indicators. This study simulates extreme cold spells of 15 days using a Stochastic Weather Generator (SWG) based on circulation analogues and importance sampling, adapted for CMIP6 data. Our results show that the most extreme cold spells decrease in intensity with global warming, making 20th-century-like events (e.g. 1985 in France) nearly impossible by the end of the 21st century. However, some events of similar intensity may still occur in the near future. Such events are associated with patterns of atmospheric dynamics that convey cold air from high latitudes into Europe. Those atmospheric circulation patterns show a consistent high-pressure system over Iceland and a strong low-pressure system over southwestern Europe in ERA5 and CMIP6 models. We show that nudging the SWG towards this type of pattern triggers extreme cold spells, even in a warmer world. We also evaluate the ability of CMIP6 models to represent such an atmospheric pattern. This study highlights the importance of understanding cold spell dynamics and the relevance of rare events algorithms and large ensemble models to simulate low-probability, high-impact events, offering insights into the future evolution of cold extremes.