bluuebunny/crossref_metadata_2025 huggingface dataset:
Functional Low-fat Set Yogurt Enhanced with Microbial Exo-polysaccharides-mediated Anticancer Activity
Authors: Khider Manal , El-Readi Mahmoud Zaki , Abdalrahim Salah , Zohri Abdel Naser , Ibrahim Ibrahim M. , Abulreesh Hussein H. , Ahmad Iqbal , Elbanna Khaled
Published: October 2022

Exopolysaccharides (EPSs) are novel functional additives for low-fat yogurt. Pharmaceutical, medical, and food industries are using more LAB-based EPSs. In this study, Leuconostoc spp. was used to produce ninth bacterial EPSs in a modified molasses medium. Production of EPSs was concentration-dependent on all stains and the highest yield was obtained from the S3 strain (55.23 g/l), followed by S6 (49.95 g/l), S8 (45.68 g/l), and S7 (44.23), respectively. HPLC and FTIR analysis showed that all purified EPSs from Leuconostoc citreum (S3) and Leuconstoc holzaapfelii (S8) were related to exopolysaccharide glucan. Anticancer activity of all EPSs samples (EPSs1-9) against Caco-2 cells and normal MCR-5 cells were investigated using MTT assay. The results revealed that Caco-2 cells were more sensitive than the normal MCR-5 cells. The highest anticancer activity against Caco-2 cancer cells was recorded for EPS8 (IC50 = 22.94 µg/ml, SI=3.73), followed by EPS3 (IC50 = 36.15 µg/ml, SI=8.72), EPS1 (IC50 = 50.01 µg/ml, SI=3.73), and EPS4 (IC50 = 94.90 µg/ml, SI=3.26), respectively. The lowest cytotoxicity was recorded for EPS5 (IC50 = 130.5 µg/ml). The most active EPSs (EPS3 and EPS8) were used as fat replacements and stabilizers in low-fat set yogurt at non-toxic concentrations (0.4, 0.8, and 1.2%). EPS3 and EPS8 improved the low-fat yogurt’s organoleptic and rheological properties. EPS8 had the highest water holding capacity (77.26%), viscosity (3660 CP), and lowest syneresis (22.95%) and whey off (0.6 ml). Low-fat set yogurt enhanced with EPS3 and EPS8 recorded the highest sensory evaluation values with overall acceptability, especially EPS3b, EPS3c, EPS8c, and EPS8b; the total score point of 97.50, 97.43, 96.51, and 96.36, respectively in fresh age compared to control yogurt (92.64). In conclusion, Leuconostoc EPSs, especially EPS8, can be explored for anti-cancer effects on Caco-2 colorectal cancer cells. It could also improve the rheological and organoleptic qualities of low-fat set yogurt.
Experimental Study on Thermal Performance of Dual Diameter Closed Loop Pulsating Heat Pipe Using ZnO/water Nanofluid
Authors: Harne Shreyas R. , Mohod Prof. R. S.
Published: October 2022

Abstract: In this paper, experimental study on the thermal performance of closed loop pulsating heat pipe (CLPHP) with single diameter and dual-diameter structure is investigated. The CLPHP with dual-diameter configuration is made of copper capillary tubes with two diameters; greater in the condenser section (inner diameter of 3mm) and smaller in the evaporator and adiabatic sections (inner diameter of 2mm). Experiment was conducted in vertical orientation with bottom heating mode having two-turns and 50% filling ratio (FR). The water and zinc oxide (ZnO/water) nanofluid with 0.25% and 0.5% w/v used as working fluids. The heat power was supplied from 8 W to 80 W, in the steps of 8 W. The various temperatures were recorded on the outer wall of the evaporator and condenser section of single diameter and dual diameter CLPHP. The thermal performance is measured in terms of thermal resistance. The thermal resistance at different heat inputs was measured. It is concluded that, the thermal performance of the dual-diameter configuration is better than the single-diameter.
Review of the monograph “The Idea of Good in F. М. Dostoevsky’s Work and Its Influence on the Development of the Philosophy of Law (To the 200th anniversary of F. М. Dostoevsky)”
Authors: Kirilenko V. P. , Mishalchenko Yu. V. , Dovbush T. N.
Published: October 2022

The collective monograph “Тhе Idea of Good in F. М. Dostoevsky’s Work and Its Influence on тhе Development of the Philosophy of Law (To the 200th anniversary of F. М. Dostoevsky)” has become a significant event in the world of world science that studies issues of international law.Within the framework of this book, great attention is paid to the opposition of the multivector forces of “Good — Evil” in relation to the Russian Federation through the work of F. M. Dostoevsky. Now, on the western borders of the Russian Federation, the actions of a number of western unfriendly states that are members of the NATO military bloc have intensified, which, from the point of view of F. M. Dostoevsky abandoned God and bring evil, vices and death to the whole world. At the same time, the Russian Federation faced an ideological vacuum after the fall of the USSR and the rejection of socialist ideals. The authors show that Russia can offer the world a new civilizational ideology of Good within which there will be a spiritual transformation and liberation of mankind from temptations, strengthening of faith in God, the establishment of Christian love and virtue. The development of the ideology of Good is becoming the historical mission of Russia in the 21st century.
Formation of Social and Political Potential of Young People in Conditions of Internet Socialization
Authors: Malik E. N.
Published: October 2022

The purpose of this study is to comprehensively understand the role of mass media in the formation of political consciousness and socio-political guidelines of modern youth. The opportunities of electronic media to increase the degree of interactive participation of the younger generation in social and political life are revealed. The main risks and threats posed by networked information and communication technologies have been identified through systematic analysis. In the course of the study, the author substantiates that the political consciousness and behavior of modern youth is formed with the growing influence of the mobilization component of the global Network, i.e., “mediatization” and “internetization” of social life. It is argued that the problems of hygiene of media policy, media literacy and improving the information culture of young people remain relevant, given the new challenges of world politics. The propaganda of destructive models of socio-political activity, extremism and terrorism on social networks, as well as the lack of censorship of a significant part of the Internet information space, remains a social problem. It is justified that media educational technologies to increase media literacy and media culture of young citizens contribute to the implementation of their socio-political subjectivity and initiative. Legislative measures aimed at creating an effective and operational mechanism to suppress the dissemination of illegal and destructive information in social media are indicated.
Challenges threaten, opportunity awaits hyperbaric medicine and the head and neck cancer patient
Authors:   National Baromedical Services, Columbia, South Carolina, U.S., Clarke Richard
Published: October 2022

Over the past four decades, hyperbaric oxygen (HBO2) therapy has played a prominent role in both the prevention and treatment of mandibular osteoradionecrosis (ORN). It has done so on the strength of laboratory observations and clinical reports, yet only limited efficacy data. This dual role has come under increasing scrutiny in the modern radiotherapy (RT) and surgical eras. The ability to spare healthy “non-target” tissue has markedly improved since the two-dimensional planning and delivery techniques in use when HBO2’s prophylactic value was first demonstrated. A recent study failed to identify this same benefit in patients who received high-precision imaging and conformal RT. HBO2 therapy is under challenge as preferred treatment for early stage ORN. A recently introduced “fibroatrophic” mechanism contrasts with the hypovascular-hypocellular-hypoxic injury pattern that formed the basis for HBO2’s therapeutic use. This alternative pathophysiologic state appears to benefit from an oral antioxidant medication regimen. The continuing necessity of HBO2 in support of mandibular reconstruction for advanced ORN is in question. Microsurgery-based vascularized bone flaps increasingly represent standard care, invariably in the absence of perioperative HBO2. Renewed interest in hyperbaric oxygen as a radiation sensitizer offers some promise. Hypoxia remains a critical radio-resistant factor in many solid tumors. Malignant gliomas have been a primary focus of several small studies, with resulting improvements in local control and median survival. Hyperbaric radiation sensitization has recently addressed oropharyngeal cancer. Preliminary data indicates that addition of HBO2 to chemo-radiation standard of care is technically feasible, well tolerated and safe. A Phase II efficacy trial will investigate the potential for of HBO2 to improve progression-free and relapse-free survival in newly diagnosed locally advanced head and neck cancers. What follows is a review and summary of relevant peer-reviewed literature.
Real-time heart rate variability analysis as a means of hypercapnia detection
Authors:   International Board of Undersea Medicine, Medical Engineering, University of South Florida, Tampa, Florida U.S., Dituri Joseph , Siddiqi Farhan ,   FAST MD, Tampa Florida U.S., Frisina Robert ,   Medical Engineering University of South Florida, Tampa, Florida U.S.
Published: October 2022

We hypothesized that heart rate variability (HRV) can be used as a physiological monitor of exposures to hypercapnia. HRV was analyzed in 15 male subjects breathing air and then air plus 4%, 5% or 6% carbon dioxide (CO2). A progressive elevation in randomness of HRV best depicted as a divergence of data on Poincaré plots of self-similarity occurred as CO2 increased, and resolved when returning to ambient conditions. Results indicate that HRV may be useful as a prompt (< 2 minute) early warning of hypercapnia that occurs prior to overt symptomatology.
Hyperbaric oxygen is still needed in the management and prevention of mandibular necrosis: a response to Mr. Richard Clarke
Authors:   Oral and Maxillofacial Surgery, University of Miami Miller School of Medicine, Miami, Florida U.S., Marx Robert E. , Feldmeier John J. ,   Radiation Oncology, University of Toledo, Toledo, Ohio U.S., Johnson Robert P. ,   Oral and Maxillofacial Surgery Wilford Hall USAF Medical Center, Lackland AFB, Texas
Published: October 2022

Mr. Richard Clarke presents in this Journal his arguments against continued application of hyperbaric oxygen (HBO2) therapy to the pre-extraction neoadjuvant treatment or the treatment of frank mandibular ORN. In the same article he advocates a promising renewed interest in HBO2 as a radiosensitizer. Arguments against HBO2 prior to extractions are based on several papers which consistently include low-risk patients. The just-released HOPON trial reports a negative pre-extraction outcome for HBO2, but patients were enrolled with radiation doses as low as 50Gy. For advanced mandibular necrosis (Marx Stage III) requiring resection, fibular free flap reconstruction is advocated. A high complication rate with free flaps is acknowledged but the magnitude of these complications is not discussed. A cost savings for this procedure is suggested, but no mention is made of the typical cost of the procedure ($90,000) or the requirement of a typical one-week hospital stay, including an initial one or two days in the ICU. Nor is mention made of the very low rate of subsequent dental rehabilitation. The success reported by Delainian, et al. employing pentoxifylline, Vitamin E and sometimes a bisphosphonate is equated to the four decades of HBO2 success with the Marx protocol for Stage I and II ORN. In the phase II trial by Delainian (not randomized) six of her 54 patients died secondary to sepsis, and she graded patients as complete responders if 5mm or less bone was exposed. Even at entry patients had an average of only 1.7 cm exposed bone and treatment was prolonged (16 + or –9 months). Any cost comparison studies will have to account for the indirect expenses of this prolonged treatment including lost productivity.
Anti-glycoprotein autoantibodies are related to bleeding severity in children with newly diagnosed ITP and very low platelet counts
Authors: Dong Shuyue , Gu Hao , Zhang Jialu , Fu Lingling , Xie Xingjuan , Ma Jingyao , Ma Jie , Chen Zhenping , Wu Runhui
Published: October 2022

Background and Objective: Immune thrombocytopenia (ITP) is an
autoimmune-mediated hemorrhagic disease. Anti-glycoprotein
autoantibodies play a key role in the pathophysiology of ITP, but the
relationship between platelet-specific antibodies and bleeding severity
is unclear. This study aimed to analyze the relationship between
anti-glycoprotein autoantibodies and bleeding severity in children with
newly diagnosed ITP and platelet count <10×109/L.
Method: This was a single-center prospective observational
study that analyzed children with newly diagnosed ITP and platelet count
<10×109/L between June 2018 and September 2021 at our
hospital. The children were classified into the mild and severe groups
based on the bleeding scores. The type and titer of anti-glycoprotein
autoantibodies were detected using an ELISA kit (PAKAUTO). We analyzed
the relationship between bleeding severity and anti-glycoprotein
autoantibodies. Results: A total of 86 cases were enrolled,
including 42 in the mild group and 44 in the severe group. Patients with
anti-GPIIb/IIIa or anti-GPIb/IX antibodies suffered more severe bleeding
than patients without them (c2=7.303, p=0.007; c2=3.875, p=0.049), but
there was no significant difference between patients with or without
anti-GPIa/IIa antibody (c2=0.745, p=0.388). When antibodies were
analyzed together, patients with three antibodies suffered more severe
bleeding than those without three antibodies (c2=5.053, p=0.025).
Patients with higher antibody titer in the eluent, but not in the
plasma, suffered more severe bleeding in all three antibodies (Z=-2.389,
p=0.017; Z=-2.108, p=0.035; Z=-2.557, p=0.011). Conclusion:
Anti-glycoprotein autoantibodies led to more severe bleeding in children
under 18 years of age without drug treatment with newly diagnosed ITP
and platelet count <10×109/L.
Program activities for sustainable rural development: Case study, village Berbatovo, Nis
Authors: Randjelovic Masa
Published: October 2022

This paper deals with the analysis, proposals, and development of program actions and measures aiming at a sustainable development of the village of Berbatovo. Development problems and potentials are defined in addition to collecting general data about the village and its development characteristics. The main shortcomings of the analyzed village are the decline in the number of its inhabitants due to their migration to cities, low education level of those who choose to stay in the village. There is not enough adequate space for public gatherings, there are no institutions necessary for functioning of the locals, such as outpatient clinic, post office, kindergarten, roads are in bad condition. Apart from producing for their own needs only, the local population shows insufficient activity and interest in starting their own business, which would create the conditions for a better quality of life in the village. In this paper, after defining development problems and observed potentials, appropriate strategic directions of sustainable development, general and specific goals and program actions and measures that would contribute to the adequate development of the village were selected.
Morphological homoplasy and sectional polyphyly in Centaurea sect. Cynaroides and related taxa
Authors: Bona Mehmet , Hughes Mark
Published: October 2022

Building natural classifications for genera with complex morphological
variations such as Centaurea needs the support of molecular analysis and
knowledge of morphological character diversification. Here we use parsimony
and Bayesian analyses of nuclear ribosomal ITS sequences to gain insight
into the sectional relationships and character evolution in Centaurea
sections Chartolepis, Cheirolepis, Cynaroides, Grosheimia, Microlophus,
Paraphysis, Phaeopappus, Plumosipappus, Pseudoserida, Pseudophaeopappus,
Ptheracantha, Ptosimopappus, and Rhizocalathium, from Turkey. In particular,
we increase sampling in Turkish endemic species of Centaurea sect.
Cynaroides and related taxa. The new ITS sequences for 26 taxa from 48
locations are given. Sequences of 17 taxa are given here the first time. The
phylogeny derived from ITS data provides a reasonably resolved and
reasonably supported phylogenetic framework for the genus. Our analysis
shows characters traditionally used in Centaurea taxonomy such as flower
colour, appendage width, spine length, and pappus length evolved several
times independently and show a lot of homoplasies. However, we can confirm
the validity of character combinations for a reliable subgeneric
classification of Centaurea.
Effects of various dormancy breaking treatment on seed germination in Sclerorhachis leptoclada boiss: an endangered medicinal plant in arid area
Authors: Mahmoudi Maliheh , Seghatoleslami Mohammad , Moosavi Gholamreza , Teimouri Mozhgan
Published: October 2022

The aim of this study was to investigate the effect of pre-sowing treatments
and temperature on Sclerorhachis leptoclada Boiss. seed germination. The
following treatments were used), hot water (soaking in water at 70?C and
90?C for 5 second), Moist Chilling (Soaking in water at 2?C for 7,14 and
21day with the temperature gradually falling to room temperature),
scarification by 0.2% potassium nitrate (soaking for 24 h and 48 h) and
Gibberellic acid (GA: at concentrations of 250, 500 and 750 ppm soaking for
24 h and 48 h) and Distilled Water (control). The percentage of germination,
germination rate, germination start (GS), mean germination time (MGT), and
germination vigor index were determined as germination indices. Root and
shoot length, root fresh weight, root dry weight, shoot fresh weight, shoot
dry weight and seedling dry weight were evaluated as growth factors at the
end of the incubation period. Second experiment was carried out to study the
effect of temperature on seed germination. It was observed that both the
physical and chemical scarification methods were effective in enhancing S.
leptoclada seed germination and growth. The highest germination rate,
percentage of germination and germination vigor index was observed with
Moist Chilling (Soaking in water at 2?C for 14 day), 0.2% potassium nitrate
(soaking for 48h) and GA (at concentration of 250 ppm soaking for 48h) in
compare with control. Also the highest growth factors were found in Moist
Chilling (Soaking in water at 2?C for 7day) treated seeds and the lowest
occurred in hot water treatments. The other results showed that higher
temperature was more effective lower temperature for seed germination.
Genetic variability, heritability and interrelationship in salt-tolerant lines of T. Aman rice
Authors: Kulsum Ummy , Sarker Umakanta , Rasul Md.
Published: October 2022

Twenty salt-tolerant breeding lines of T. Aman rice were studied under field
conditions at the experimental farm of the Department of Genetics and Plant
Breeding, Bangabandhu Sheikh Mujibur Rahman Agricultural University,
Bangladesh. The experiment was conducted following Randomized Complete Block
Design (RCBD) with three replications to estimate the genetic variations in
yield and yield-related traits, and their interrelationship and to assess
the direct and indirect effects of different yield-related traits on grain
yield for the selection of high-yielding T. Aman rice. Twelve characters
viz., days to flowering, days to maturity, plant height (cm), tillers per
hill, panicles per hill, flag leaf length (cm), panicle length (cm), panicle
weight (g), filled grains per panicle, spikelet fertility percentage,
100-grain weight (g) and grain yield per m2 (kg) were studied. The genotypes
differed significantly for all the traits studied indicating the wide range
of variations existed across the genotypes. The analysis of variance of all
characters studied was highly significant that revealed a wide range of
variability among the newly developed 20 salt-tolerant genotypes of T. Aman
rice. The genotypes BU1, BU4, BU6, BU7, and BU14 had high grain yields and
could be directly selected as high-yielding varieties. Based on all genetic
parameters, all the traits could significantly improve the grain yield of
salt-tolerant lines of T. Aman rice. The correlation coefficient revealed
that the genotype selected based on days to flowering, days to maturity,
plant height (cm), panicles per hill, flag leaf length (cm), panicle weight
(g), filled grains per panicle, and spikelet fertility (%) and 100-grain
weight directly would significantly contribute to grain yield of 20
salt-tolerant genotypes of T. Aman rice. However, considering the genotypic
correlations and path coefficients, direct selection on the basis of
panicles per hill, panicle weight, plant height, flag leaf length, filled
grains per panicle, spikelet fertility (%), days to flowering, and days to
maturity would significantly improve the grain yield of salt-tolerant T.
Aman rice genotypes.
Analysis of COL1A1 and MMP9 single nucleotide polymorphisms in mandibular prognathism
Authors: Milosevic Olga , Nikolic Nadja , Carkic Jelena , Majstorovic Nemanja , Glisic Branislav , Milasin Jelena
Published: October 2022

Mandibular prognathism (MP) belongs to malocclusions of skeletal Class III
and is characterized by overgrowth of the lower jaw with or without
undergrowth of the upper jaw. MP etiology is multifactorial, including both
environmental and genetic factors. It is conceivable that single nucleotide
polymorphisms (SNPs) in genes controlling craniofacial development might
contribute to MP. The aim of the present study was to establish a potential
association between COL1A1 -1997 G>T (rs1107946) and MMP9 -1562 C>T
(rs3918242) SNPs and MP in Serbian population. This case-control study
included 120 participants: 60 patients with MP and 60 controls with skeletal
Class I. The two SNPs were analyzed by means of polymerase chain
reaction-restriction fragment length polymorphism (PCR-RFLP) method. The
association of gene variants with MP risk was determined by calculating odds
ratios (OR) and their 95% confidence intervals (CI).There was no difference
in SNPs allele frequencies, and no difference could be observed in MMP9
-1562 C>T genotypes distribution between cases and controls. However, the TT
genotype of COL1A1-1997 G/T (rs1107946) polymorphism was associated with a
two-fold increase of mandibular prognathism risk, though with a borderline
statistical significance (OR 2.32, CI 0.97-5.53, p=0.055). COL1A1-1997 G/T
(rs1107946) appears to be implicated in Class III mandibular prognathism
while MMP9 -1562 C/T (rs3918242) does not seem to be a risk factor for the
development of this type of craniofacial anomaly.
Response of wheat genotypes to excess boron estimated by in vitro culture
Authors: Kondic-Spika Ankica , Glogovac Svetlana , Trkulja Dragana , Marjanovic-Jeromela Ana , Marjanovic Milica
Published: October 2022

The objective of this study was to evaluate boron tolerance of wheat
genotypes using mature embryo culture. The analysis involved 79 recombinant
inbred lines of the International Triticeae Mapping Initiative (ITMI)
population and three Serbian varieties with known boron (B) tolerance
(Pobeda - sensitive S, Balerina-medium tolerant MT, and Nevesinjka -
tolerant T). The evaluation was performed on a modified MS medium to which
15 mM of boric acid was added. The control medium contained no excess B.
Callus fresh weight (CFW) and reduction of fresh callus weight (RFCW) were
determined after one month of cultivation. ANOVA has shown highly
significant effect of genotype, the media, and their interaction to callus
tissue growth and also significant genotypic effect on RFCW. Majority of
genotypes (39) had sensitive reaction to excess boron, twenty-three were
medium tolerant, while four of them were tolerant. The obtained results can
be potentially used for mapping QTLs associated with tolerance to excess B
in wheat breeding program.
Behavior of melt flow and porosity formation in laser welding of steel to aluminum with cold-sprayed steel interlayer
Authors: Maeda Kyohei , Sato Yuji , Takenaka Keisuke , Fujio Shumpei , Suzuki Reiichi , Suga Tetsuo , Tsukamoto Masahiro
Published: October 2022

A multimaterial car body design, using light materials in combination with steel, has become widespread in recent years in order to reduce a vehicle's weight. The joining of dissimilar materials is one of the most critical issues in this area. In our previous research, we reported on a new dissimilar laser lap joining method, using a cold-spray process. In that procedure, a steel coating was first sprayed onto an aluminum surface, after which a steel sheet, together with the coating, was laser welded. However, it was found that porosity occurred in the weld metal due to melting of the coating. In this study, we investigated the effects of welding parameters on porosity formation in this joining process as well as the behavior patterns of the flow and bubbles in a molten pool. The porosity increased as the laser input energy decreased. It was also discovered that the porosity could be reduced drastically by the melting of the aluminum substrate, together with the steel sheet and coating, even at lower input energy. Electron probe microanalyzer results showed that both the solidification rate, related to the input energy, and aluminum's melting were strongly associated with the generation of flow from the bottom to the surface of the molten pool. This was captured by means of an x-ray in situ observation, using tungsten tracers, behind the keyhole. The bubbles, moving upward and reaching the surface of the pool, were also observed there in the welding conditions, where only a little porosity occurred. These results demonstrated that this flow helped the bubbles move up and go outside the molten pool and, hence, prevented porosity formation.
Expanding the capabilities of laser-based powder bed fusion of polymers through the use of electrophotographic powder application
Authors: Kopp Sebastian-Paul , Medvedev Vadim , Frick Thomas , Roth Stephan
Published: October 2022

Generating multimaterial parts, reaching higher efficiency in powder consumption, and decoupling of powder application behavior from powder properties such as powder flowability are key aspects for using electrophotographic powder application (EPA) in laser-based powder bed fusion of polymers (PBF-LB/P). Moreover, EPA allows the layer thickness to be reduced from around 100–150 μm, depending on respective particle size distribution, in the case of conventional doctor blade or roller-based powder application methods to the diameter of the applied polymer particles (typically between 50 and 130 μm). This can have positive effects on the interlayer connection and, therefore, the mechanical properties of the additively manufactured part because less powder volume has to be fused with the already generated underlying part. Moreover, due to the above-mentioned independence of EPA from powder flowability, the addition of flow aids, such as nano silica, can be reduced to a minimum or even avoided completely. This is the first comprehensive study on resulting properties of parts generated by PBF-LB/P using EPA taking into account both the reduction in layer thickness and reduced addition of flow aids. In addition to improving mechanical properties of generated parts, the independence of powder flowability, in particular, offers the possibility of qualifying currently unsuitable materials for PBF-LB/P. For this purpose, besides widely employed polyamide 12 (PA12), a polypropylene (PP) powder is used that is very difficult to process in conventional PBF-LB/P and can only be applied there with the help of flow aids.
Digital Comic Media: Pancasila Relationships in Daily Life
Authors: Aprillia  , Dewi Ratna Sari , Setiawan Sigit
Published: October 2022

The position of learning media is very important as a tool in conveying material that the teacher cannot explain. However, often the use of learning media that are rarely used can harm teachers and students. This research aims to create a digital comic media of Pancasila relations in the daily life of Civics learning subjects in grade IV. This type of research is development research using the development stage of the Borg and Gall. The research subjects were two linguists, two material experts, and two media experts and student responses. Methods of data collection with interviews, observations, questionnaires, and documentation. The data collection instrument is a questionnaire instrument. The analysis technique is quantitative and qualitative analysis. The analysis results of linguists obtained 68% in the proper category. The results of material experts obtained a percentage of 79.41% in the feasible category. Expert validation results in a percentage of 85.62%, which fall into the very feasible category. The questionnaire participants' responses were 93.2% in the very feasible category. Thus, the digital comic media of Pancasila relations in everyday life deserves to be used. The implications of this research are expected to help teachers provide information to students related to Pancasila relationships in everyday life.
Powtoon Animation Video Based on Contextual Approach in Elementary School Mathematics Learning
Authors: Sari Ni Kadek Candra Permata
Published: October 2022

The lack of media or supporting tools in teaching and learning activities and the lack of material presented make the learning process less meaningful. It can cause the learning process to be less effective, and students will become less familiar with the material being taught. This study aims to develop learning media in animated Powtoon videos based on a contextual approach to learning the circumference and area of ​​a triangle for fourth-grade elementary school students. This research is development research that uses the ADDIE research model. The method used in this study is a questionnaire with the provision of an assessment sheet instrument given to 2 lecturers as material experts, two lecturers as media experts, two teachers as practitioners, and five students. The instrument used in this study is a rating scale. The data that has been obtained will then be analyzed using the Mean formula to get an average media validity score. The results of the average value of the validity of the Powtoon animation video media based on the contextual approach from material experts was 4.83 with very good qualifications, from media experts 4.83 with very good qualifications, from practitioners 4.83 with very good qualifications, and student response of 4.75 with very good qualifications. So it can be said that the Powtoon animation video learning media based on the contextual approach developed in learning the circumference and area of ​​a triangle is valid and can be used in learning for fourth-grade elementary school students.
The Relationship of Curiosity, Confidence, and Kinesthetic Learning Styles with Interest in Science Learning
Authors: Gitatenia I Dewa Ayu Indah , Lasmawan I Wayan
Published: October 2022

The student’s curiosity, self-confidence, and interest in learning science are still low. This situation is also supported by the teacher's way of teaching, which is less attractive so that students feel that science lessons are so boring. This study analyzes the relationship between curiosity, self-confidence, and kinesthetic learning styles interested in learning science. The type of research conducted is the type of ex-post research. This population is 326 students. Determination of the sample in this study using a random sampling technique with the required number of samples, as many as 167 students. The method used in this research is the non-test method. The instrument used is a questionnaire. The data analysis technique used is inferential statistical analysis. This research shows that the significance of curiosity is 0.000 < 0.05, so curiosity has a significant positive relationship with interest in learning science. The significance of self-confidence is 0.024 <0.05, so self-confidence has a significant positive relationship with interest in learning science. The significance of the kinesthetic learning style (x3) is 0.047 < 0.05, so the kinesthetic learning style is significantly positively related to the interest in learning science. It was concluded that curiosity, self-confidence, and kinesthetic learning styles had a significant positive relationship with interest in learning science.
Contextual-Based E-Book on Balinese Script Writing Learning Materials
Authors: Maharani Alifia , Suniasih Ni Wayan
Published: October 2022

The lack of interactive teaching materials used to support Balinese language learning activities causes students to lack understanding of the material and be less interested in learning the Balinese language. This study aims to create teaching materials in the form of a contextual-based e-book suitable for fourth-grade elementary school students. This study uses the ADDIE development model, which consists of 5 stages, analysis, design, development, implementation, and evaluation. The types of data collected in this study are quantitative data and qualitative data. The subjects in this study were one subject matter expert, one learning design expert, one learning media expert, and 12 elementary school fourth-grade students. The method of data collection uses the questionnaire method. The teaching material in the form of this e-book is declared eligible by obtaining the percentage results from the subject matter expert test with very good qualifications (95%), the learning design expert test with very good qualifications (91.7%), the learning media expert test with very good qualifications (90 %), individual trials with good qualifications (85%), and small group trials with good qualifications (88.8%). It can be concluded that the contextual-based e-book on the local content of writing Balinese script for the fourth grade is declared feasible to be used in the Balinese language learning process.
The Value of Character Education in a Collection of Fairy Tales by Ungu Lianza
Authors: Mutiara Helmi , Yatri Ika
Published: October 2022

Fairy tales have moral values ​​that can be used as an alternative to character learning in children. Fairy tales can provide information related to the value of character education. This study aims to analyze the value of character education in the collection of fairy tales by Ungu Lianza in grade 2 elementary school. This research is a qualitative method using the literature description of the library—methods of data collection using interviews and documentation. Qualitative research in this study was conducted by collecting data by observing the situation that occurred following the circumstances without being manipulated or influenced. The data analysis technique used qualitative analysis a collection of fairy tales by Ungu Lianza and the implications of character values ​​in everyday life. Grade 2 students in everyday life apply character values, increase interest in reading story books through the Ungu Lianza fairy tale book, and understand the values ​​of other characters. Teachers can also put in the personality values ​​of students to have the traits of tolerance, cooperation, independence, discipline, responsibility, and integrity. This research implies that teachers in the learning process can apply character education through fairy tales to students. So it can be applied in everyday life.
Operative management of intracerebral hemorrhage: 3 year experience in multidisciplinary city hospital
Authors: Mammadinova Iroda , Talasbayev Murat , Maidan Aiman , Kali Yermek , Duissenbayev Yerkin , Zholbaryssov Rustem , Nuradilov Saken
Published: October 2022

Hemorrhagic stroke is a hemorrhage in the brain parenchyma or ventricles resulting from a rupture of an intracerebral vessel or increased permeability of its wall. Intracerebral hemorrhage is a serious medical and social problem associated with high mortality and disability worldwide. Our study aimed to analyze the operative treatment results of patients with hemorrhagic stroke to determine the factors influencing mortality.
Pengaruh Model Pembelajaran Inkuiri Dan Creative Problem Solving Terhadap Hasil Belajar Siswa MTS Medan Tembung
Authors: Fatmawati Sari , Tanjung Indayana Febriani , Khairuna Khairuna
Published: October 2022

This study aims to determine the effect of the inquiry learning model and the creative problem-solving learning model on student learning outcomes. This research was conducted at MTs Madinatussalam Tembung for the academic year 2020/2021. The research method is quasi-experimental. The sample used in the study was 60 students, the sampling in this study was simple random sampling. The instrument in the study used a pretest and posttest. Based on the results of the research, the results of hypothesis testing on the results of the Inquiry class hypothesis test. From the table above, the value of t(count )= 8,594 and the value of t_(table )= 2.0243 so that t_(count)>t_(table) which is therefore Ho is rejected. Ha accepted. Based on the results of hypothesis testing, there is an influence of the inquiry learning model. The results of the hypothesis test for the Creative Problem-Solving class. From the table above, the value of t(count )= 8, 683 and the value of t_(table )= 2.0243 so that t_(count )>t_(table ) which means that Ho is rejected, Ha is accepted. Based on the results of hypothesis testing, there is an influence of the Inquiry learning model and Creative Problem-Solving learning model on student learning outcomes at MTs Madinatussalam Medan Tembung.
The Place and Importance of Op Art In Graphic Design Education With Its Interdisciplinary Art Education
Authors: İNCEAĞAÇ Muhammet , TUNA Serdar
Published: October 2022

Purpose: The aim of the research is to reveal graphically the convertibility of the Op Art movement into graphic design studies by students and how this transformation is interpreted.
Methodology: In this study, the ‘Op Art’ movement from Contemporary Art was preferred as an imaginary resource in graphic design education. The research was conducted in the form of action research, one of the qualitative research methods. The research is characterized as participatory action research, one of the types of action research. The research is limited to the 2nd year students studying at Kastamonu University Kastamonu Vocational School Design Department Graphic Design Program in 2016-2017, 2017-2018, and 2018-2019. The study was conducted with 458 students who took ‘Visual Design, Publication Graphics and Typography’ courses between in the specified academic years. Since it is not possible to include all student studies, 6 student studies have been included as an example. Student studies were analyzed descriptively.
Findings: As a result of the study, it was observed that the students were able to transform the Op Art movement into graphic design products, to interpret different types of works from a subjective point of view by considering the characteristics of the movement, and to create original graphic design works suitable for the composition they wanted to design.
Highlights: Contemporary Art, which is covered in the chronology of art history, emerges as one of the most fundamental disciplines in art and design theoretically. It is very important to benefit from different disciplines in graphic design education, to increase the interest in design courses, and to reveal original and creative designs. From this standpoint, it can be assumed that Contemporary Art can be one of the richest resources to be used in terms of art and design. In this study, Op Art art movement, one of the Contemporary Art movements, was used in terms of creating a resource for graphic design education courses.
Investigation Of The Effects Of Tinkercad Based Stem Implementations On Computational (Computer) Thinking Skills And Technology Use Standards Of Teacher Candidates
Authors: KARABULUT COŞKUN Burcu , BOZDEMİR YÜZBAŞIOĞLU Hafife , AŞKIN TEKKOL İlkay
Published: October 2022

Purpose: This study investigates the effect of STEM implementations on computational thinking skills and technology usage standards of classroom teacher candidates. The experimental method “One-group Pretest-Posttest Design” has been used in the study. In line with the purpose of the study, data on Computer Thinking Skills and Technology Use Standards of pre-service teachers who participated in STEM education practices for 11 weeks were collected and analyzed at the beginning and end of the procedure.
Design/Methodology/Approach: The experimental method “One-group Pretest-Posttest Design” has been used in the study. Ninety pre-service teachers who took Science and Technology Laboratory Practices I and II courses from Kastamonu University Faculty of Education and the primary school teaching department participated in the study.
Findings: According to the results of the study, while it was seen that the candidates for STEM implementations were not generally effective in their classrooms, their preferences in one of the nearby backgrounds from one of the sub-dimensions considered only by the computer.
A New Roadmap for Reskilling and Upskilling (R&U) in Türkiye: Vocational Training Center Skill Development Programs
Authors: ÖZER Mahmut , SUNA H. Eren
Published: October 2022

Purpose: The skills that adults possess are very important for their adaptation to the technological transformation and contribution to the economy. Therefore, large-scale projects are implemented to develop theseskills within a lifelong learning approach. The Ministry of National Education (MoNE) has initiated “Vocational Training Center (VTC) Skill Development Programs” to improve the skills within the paradigm shift in VET system. This study aims to evaluate the performance of these programs in the first six months through the data collected from the participants.
Design/Methodology/Approach: The study compares the number of students in VET skill development programs and the change of demographic characteristics in the last six months. Therefore, the data in the programs were used anonymously. The study is designed as descriptive research.
Findings: The findings show that adults demand greatly for skill development programs in just four months and the number of participants has increased from approximately 6000 to 79000. The adults aged 31 and above constituted largest share of participants. The gender distribution of the participants is quite balanced and it is mostly valid at different age levels. In addition, 19% of participants graduated from associate degree and higher education levels. This reveals that adults need to develop their skills and are in high demand regardless of their education level. The service sector and creativity-related fields are highly preferred by adults and this pattern is valid for adults from different education levels.
Highlights: VTC skill development programs have a great potential for upskilling and reskilling of adults in Türkiye. For the last six months, these programs are demanded from adults and the percentage of females have reached the peak level in VET. The fact that 19% of the participants are tertiary graduates indicates that adults who have graduated from tertiary education have a demand for acquiring new skills. The findings in the first six months show that the skills development programs reach the target group and meet an important need in skills development.
Science and Non-Science Majors’ Mental Models of Nuclear Power: Does the Program of Study Matter?
Authors:   Sinop University, Sinop (Turkey). E-mail: huseyines@sinop.edu.tr, EŞ Hüseyin , YENILMEZ TÜRKOĞLU Ayşe ,   "Alanya Alaaddin Keykubat University, Antalya (Turkey). E-mail: ayse.yenilmez@alanya.edu.tr"
Published: October 2022

"Abstract: The purpose of this study was to characterize science and non-science majors’ mental models of nuclear power plants through their drawings. For this purpose, a total of 27 Theology and 26 Science Education college students were participated in the study. To collect data, students were first asked to state their decisions about the construction of nuclear power plant in the city they live, and then to think about nuclear power plants in their minds and draw the revived images on a paper. Data were analyzed through content analysis based on the SEE-STEP model. Findings revealed that religious beliefs and/or education may affect college students’ reactions to nuclear power plants. That is, while most theology majors approached the construction of nuclear power plants positively, majority of science education majors did not. Theology majors referred mostly to economy in their drawings, while science education majors mostly to environment. Regardless of the program of study, on the other hand, the codes emerged from the drawings were mostly about environment, which was followed by technology, economics and science. Ethics was the least common subject area referred in the drawings of the students from both programs of study."
An Investigation of Turkish University Students’ Internet Addiction Level During the Covid-19 Pandemic
Authors:   ", BALTACI Onder ,   Kırşehir Ahi Evran University, Kırşehir (Turkey). E-mail: baltacionder@gmail.com"
Published: October 2022

"Abstract: The purpose of this study is to examine the level of internet addiction of university students in the coronavirus epidemic process in terms of various variables. The research was carried out with the screening model, which is one of the quantitative research methods. The study group in Turkey between coronavirus outbreak and characterized by intense social isolation process from March to April 2020 date, Turkey in different higher education institutions in studying and researching on Google Forms through volunteer who agreed to participate 113 men, 292 women It consists of a total of 405 university students. In the research, ""Young Internet Addiction Scale-Short Form"" adapted to Turkish by Kutlu et al. (2016) and ""Personal Information Form"" developed by researchers to determine demographic information were used to determine the level of internet addiction of university students. As a result of the research, internet addiction levels of university students were found low during the coronavirus outbreak days. In addition, while the internet addiction levels of university students participating in the study differ significantly according to the frequency of curfew and daily internet usage time; There is no significant difference in terms of gender, city and residence, number of family members and frequency of coronavirus anxiety. The results of the research were discussed in the light of the literature and suggestions were made."
“Memoria y esperanza”: Luis García Montero reivindica a Luis Rosales
Authors: Núñez Díaz Pablo
Published: October 2022

Luis García Montero ha contribuido de manera significativa a la recuperación de la obra de Luis Rosales. En el presente artículo, se analizará la relación entre ambos escritores y la aportación de García Montero para la reivindicación y difusión del poeta de la generación del 36. Además, se examinará la interpretación que García Montero hace de Rosales, que tiene un doble interés, por ser la interpretación de un poeta relevante y, al mismo tiempo, la de un catedrático universitario experto en poesía española contemporánea. El análisis del diálogo que García Montero ha establecido con la poesía de Rosales permitirá determinar los aspectos más significativos que vinculan sus poéticas.