bluuebunny/crossref_metadata_2025 huggingface dataset:
Erythema Infectiosum: clinical case
Authors: Pashinyan Albina G. , Runikhina N. K , Mokeeva E. Yu
Published: September 2020

Human Parvovirus B19 has been recognized as the causative agent of a wide range of diseases. The cellular receptorfor parvovirus B19 is P antigen located on the trophoblast cells, bone marrow, liver, kidney, synovium, etc. has been associated with many clinical situations, erythema infectiosum and erythroblastopenia crisis. In the absence of P-antigen, revealed no susceptibility to parvovirus infection. Infection in pregnant women under 20 weeks gestation can lead to miscarriage or non-immune hydrops, fetal death. 1-5% of women are susceptible to parvovirus infection during pregnancy. Viral infection may be responsible for aplastic anaemia in immuno-compromised patients. Diagnosis ofparvovirus infection B19 is based on the results of general blood analysis; biochemical analysis of blood; serological methods, PCR detection of IgM, immunoblot IgM/IgG. The most common clinicalform of parvovirus B19 infection in children is erythema infectiosum. It is also called “fifth disease”. Erythema infectiosum is characterized by a viral prodrome followed by the “slapped cheek’ facial rash and macula papular lace or mesh rash on the skin of the trunk and extensor surfaces.
Vitiligo: etiology, pathogenesis and therapy
Authors: Kruglova Larisa S.
Published: September 2020

Vitiligo is an autoimmune disease. The prevalence of the disease is 0.5% of the population. The main etiological factor is genetic defect of melanogenesis enzymatic system. The article is a review. The current data on the pathogenesis, classification and treatment of vitiligo are presented. Existing therapies mainly have moderate efficacy. The principal methods of treatment are ultraviolet therapy, laser therapy, topical corticosteroids and calcineurin inhibitors.
The role of correction of metabolic disorders in the treatment of androgenetic alopecia in women
Authors: Perlamutrov Yu. N , Antsiferov M. B , Levina Natalia V.
Published: September 2020

The problem of androgenetic alopecia in women is considered by experts of various specialties, however there are few reviews about metabolic processes in these patients. Objective: to increase the efficiency of treatment of androgenetic alopecia in view of metabolic abnormalities. Material and methods. 80 female patients with androgenetic alopecia were examined to identify the features of the clinical course and hormonal metabolic deviations. Results. It was found that women with the androgenetic alopecia have abnormalities in carbohydrate and lipid metabolism in the majority of cases. Combined therapy with metformin helped to increase the clinical efficacy in the treatment of women with androgenetic alopecia.
Comorbidities in psoriasis
Authors: Olisova O. Yu , Garanyan Lusine G.
Published: September 2020

The article describes the modern data on the connection of psoriasis with various comorbidities. It identifies the most frequent comorbid diseases recorded in patients, depending on the severity ofpsoriasis. Among the most common comorbidities, there are cardiovascular diseases, diabetes, metabolic syndrome, that must be considered when choosing the treatment.
Actinolizat in the treatment of the purulent-inflamatory processes of the skin and subcutaneous tissues: history and prospects
Authors: Yakovlev Alexey B. , Savenkov V. V
Published: September 2020

Actinolizat is a highly effective domestic immunomodulator with anti-inflammatory and healing action. It has been exactly 80 years since the discovery of the phenomenon of actinomycetes autolysis. Based on this phenomenon actinolizat has worked well in bacterial purulent-inflammatory skin lesions, subcutaneous tissue, organs and systems. The drug is well tolerated, and has few side effects.
Features of patogenesis, clinical presentation and treatment of actinic ceratosis
Authors: Vasenova V. Yu , Butov Yu. S , Ivanova M. S
Published: September 2020

Actinic keratosis is a precancerous condition, which occurs as a result ofprolonged or frequent exposure to UV radiation on the skin. Treatment of actinic keratosis is effective prevention of malignancy process. Photodynamic is the most modern method of treatment of actinic keratosis. 40 patients with actinic keratosis were examined and treated by the photodynamic method using 5-aminolevulinic acid (“Alasens”) and therapeutic “Biospec” flash lamp. The high effectiveness of this method is confirmed by the results of histology, acoustic study of the skin and indicators of antioxidant status.
Case of a congenital dystrophic violent epidermolysis
Authors: Dumchenko V. V , Tkachenko T. A , Bakhmutova E. G , Stepanova I. V , Lozovaya L. P , Vetoshkina Lidiya N.
Published: September 2020

Clinical case of generalized form of congenital dystrophic violent epidermolysis at the patient M., 26 age is presented. The disease constantly progressed and proceeded with the classical picture expressed by all implications and symptoms characteristic of this form of illness. Despite of treatment new organs were involved in the process: kidneys, eyes, the hemopoietic system, developed a cachexia, contractures. Quality of life considerably worsened, difficulties in movements appeared. This case shows disease severity, gravity of the implications and complications leading to disability.
PEMPHIGUS VEGETANS IMITATING SKIN CANCER
Authors: Bazaev V. T , Tseboeva M. B , Tsarueva M. S , Dzhanaev V. F
Published: September 2020

Case of a rare form of vegetating true acantholytic pemphigus with atypical manifestations on the face and scalp, interpreted as skin cancer, is described. The process was accompanied by the generation of high level of immunoglobulin G only to desmoglein type 3. This example demonstrates the difficulty in the diagnostics of true pemphigus not only for general doctors of different specialties but also for dermatologists.
INFLUENCE SIFILITIC IN PREGNANT WOMEN ON THE HEALTH OF NEWBORN CHILDREN
Authors: Matyskina Natalya Vladimirovna , Taranushenko T. E , Karacheva Yu. V
Published: September 2020

A particular challenge for child health represent cases of early and congenital syphilis, which is characterized by a severe multiorgan pathology in children and high mortality in newborns. Purpose. To study the incidence of early congenital syphilis, depending on the time of detection of syphilis infection in women and to present the clinical features of this disease in newborns with the frequency of the detection of the most important specific manifestations of the disease. Material and methods. We observed 114 women with confirmed syphilis infection and newborns from these mothers. Results. The data presented indicate the prevalence of Lues latens praecox in the structure of syphilis infection in pregnant women with newly diagnosed disease. In children from women who were diagnosed with syphilis during this pregnancy early congenital syphilis (PBC) exhibited in 74.3% of cases, while 27 cases in 19 newborns syphilis was accompanied by clinical symptoms. Conclusion. In the pathological process in congenital syphilis, with greatest frequency involved bone, followed - mucous membranes (rhinitis).
FEATURES OF THE APPLICATION OF ENZYME PREPARATIONS FOR THE TREATMENT AND PREVENTION OF POSTACNE
Authors: Ostretsova Mariya N. , Snarskaya E. S , Tkachenko S. B , Allenova A. S
Published: September 2020

Postacne is a frequent consequence of vulgar acne. In our research the possibility of using hyaluronidase-based medication with prolonged action was considered. Materials and methods. Type of study: randomized, double-blind, placebo-controlled, comparative in parallel groups. 78 patients aged 18 to 35 years with moderate and severe acne vulgaris and postacne scarring were observed, patients were divided into 2 groups of 39 each by randomization. The first group received Bovhyaluronidase + Azoximer (HA) 3000 ME, the second group received a placebo. In accordance with the method of administration within the groups, patients were divided into subgroups. The drug or placebo was administered by intramuscular injection into the gluteus muscle (N = 10, 1 per 3 days) or by ultraphoonophoresis (N = 15, daily). Evaluation of the skin was performed by confocal laser scanning microscopy (CLSM) in vivo (VivaScope 1500, “Lucid Inc.”, USA) and laser Doppler flowmetry (LDF) (LAKK-01 laser capillary blood flow analyzer, “LAZMA”, Russia). The effectiveness was evaluated by the Qualitative scaring grading system and Goodman’s quantitative global acne scarring system. Results. With the use of Bovhyaluronidase + Azoximer 3000 ME improvement was in 84.6%, 5.13% of patients had a significant improvement. In the placebo group the reduction of indices was insignificant. In the drug group a statistically significant change in the microcirculation index (flux) was established. In the placebo group the dynamics of flux was less pronounced. CLSM results showed a significant decrease in fibrosis and inflammatory infiltration in the scar area in the BGA group. In inflammatory areas was reduction of fibrosis and vasodilation. In the placebo group these changes were less pronounced.
EPIDEMIOLOGY, ETIOPATHOGENESIS, COMORBIDITY IN PSORIASIS - NEW FACTS
Authors: Olisova O. Yu , Garanyan Lusine G.
Published: September 2020

Psoriasis vulgaris is a chronic recurrent genetically determined dermatosis with multifactorial nature, characterized by hyperproliferation and impaired differentiation of keratinocytes, inflammatory reaction in the dermis, immune disorders and lesions of the skin, nails, joints and other organs. The article presents a review of the current literature data on the etiology and pathogenesis of psoriasis and its association with various comorbidities, psycho-emotional and socio-economic status. Among the most common comorbidities, depending on the severity of psoriasis, there are cardiovascular diseases, diabetes mellitus, metabolic syndrome. In addition, psoriasis vulgaris often affects people of working age, leading to psychological and social desadaptation, decrease of work capacity, depressive disorder.
CLINICAL EVALUATION OF THE EFFECTIVENESS OF RADIOFREQUENCY FRACTIONAL ACTION IN INVOLUTIONAL SKIN CHANGES
Authors: Pinson Igor Ya. , Verkhoglyad I. V
Published: September 2020

The results of the study of biorevitalization effectiveness of the facial skin in women aged 30 to 40 years are presented. Material and methods. In the 1st group (n = 30) hyaluronic acid (HA) was used along the face oval, in the zone of the cheekbone, along the nasolabial folds, along the longitudinal wrinkles in the forehead area with the use of “micro-puncture” and “short-linear” techniques in the medium-deep layers of the dermis. The distance between injections is 1 cm. Injection schemes are standard, proposed by manufacturing companies - once a week, in total 6 procedures. In group 2 (n = 30), the HA was administered with the Legato apparatus, where two technologies were successively used: radio frequency and ultrasound, once every 2 weeks, with a course of 5-6 procedures. Both groups used HA in a concentration of 2 mg/ml Gialripyer-07M/mesolift. Instrumental studies of the functional properties of the skin included assessment of hydration of the epidermis (corneometry), deformation and elastic properties of the skin (cutometry), assessment of transepidermal loss of moisture (TEVA-metry), assessment of seboregulatory function of the epidermis (sebometry) using Multi Skin Test Center® MC750; dermatoscopy on a digital video camera Aramo SG, providing a computer image of the texture of the skin and its moisture level; ultrasound scanning of the skin using a digital high-definition system DUB (“TPM GmbH”, Germany) and a high-frequency linear 17 MHz sensor in SmParts Superfic scanning mode with a resolution of 78 microns. Results. The study shows the superficial effect of mesotherapy procedures: improving the morphofunctional properties of the skin, they have no effect on the thickness, echogenicity and relief of the dermis. At the same time, the obtained results of instrumental studies of the structural and functional parameters of the skin make it possible to justify the use of modern technology Legato (radio frequency and ultrasound) for intradermal administration of HA preparations, with the help of which it is possible to obtain in a short time a positive dynamics of the indices of structural and functional parameters of not only surface layers of skin, but also at the level of the dermis.
STUDY OF THE MESOTHERAPY EFFECT WITH EPIPHYSIS PEPTIDES ON THE MOISTURE AND ELASTICITY OF THE SKIN
Authors: Korolkova Tatiyana N. , Goma S. E
Published: September 2020

Introduction. Mesotherapy is a widely used method of preventing external signs of aging in cosmetology. However, drugs that have proven effectiveness are not enough, therefore epiphyseal peptides are of great interest. Purpose: is to study the effect of intradermal administration of peptide epiphysis on the functional para-meters of the skin. Material and methods. There were 38 women in the research devided into 2 comparable groups. The main group (26 persons) was treated by mesotherapy with epiphyseal peptides. Face, neck and decollete zones were treated by the method of “deep nappage” once a week, 5 procedures per course. Isotonic solution of NaCl was similarly injected into the neck and decollete areas of the control group (12 people). The moisture content (Corneometer CM 825, “Courage & Khazaka”, Germany) and the elasticity (Cutometer MPA 580, “Courage & Khazaka”, Germany) of the skin were determined. Functional skin parameters were evaluated before and after treatment (in both groups) and also on the 1st and 6th months after mesotherapy in the main group. Results. Under the influence of epiphysis peptides the moisture content of the skin increases by 10% after treatment (in the control group without changes) and after 1 month, then decreases by 5% in 6 months below the initial values. In the main group R0 and R8 parameters increase immediately after treatment by 21% and 20% (in the control group R0 and R8 decrease by 4-6%), then decrease by 6-7% and by 28%. The R4 parameter increases immediately after treatment by 20-25% (in the control group it decreases by 13%), then decreases by 12% and 24%; F0 and F1 parameteres increase immediately after treatment by 17% and 22% (in the control group they decrease by 4% and 3%), then decrease by 11% and 9%, by 25% and 28%. Conclusion. The revealed dynamics of skin functional indexes may support the stimulating effect of peptide epiphysis on the cellular elements of the dermis (activation of metabolic processes after treatment and improvement of elasticity parameters by 25-28% after 6 months). Mesotherapy with epiphyseal peptides can be recommended as a method of prevention and correction of age-related skin changes.
ETIOPATHOGENETIC FEATURES OF ATOPIC DERMATITIS IN PRESCHOOL CHILDREN
Authors: Akhrorov Khusan Kh. , Nabieva D. D
Published: September 2020

Objective. To determine the most important etiopathogenetic factors of formation, with their subsequent influence on the severity of atopic dermatitis (AD) in preschool children. Material and methods. 58 children aged 2 to 5 years with AD were examined. Clinical examination of patients, a general analysis of blood and urine, koproovocystoscopy, the determination of specific IgE (to food, household, epidermal, pollen allergens) by ELISA, examination of feces for dysbiosis were performed. Assessment of clinical manifestations of AD was carried out on the bases of the SCORAD system (1997). Results. The obtained data indicated that in the severe course of the disease the first clinical signs of AD were observed already in early childhood (up to a year). Hereditary burden for allergic diseases was determined on average 74.1%, but with moderate and severe pollen sensitization was recorded - in 46.6%, epidermal - in 13.8% of patients. Factors contributing to AD aggravation in pre-school children are the food factor (72.4%), contact with plant dust (43.1%) and stressful situations (17.2%). In patients with severe disease the rates of these factors were higher from 9 to 35%. The highest incidence of co-morbidity noted among children with severe AD was 2 times higher in patients with moderate severity. Conclusion. The AD severity in children of preschool age depends directly on the simultaneous presence of several major etiopathogenetic factors. In particular, the presence of food (72.47%) and pollen (54.5%) sensitization of the organism against the background of hereditary burden on allergic diseases (90.9%) leads to disease complication, which is 9% to 35% higher than in patients with moderate to mild severity.
OPTIMIZATION OF THERAPEUTIC MEASURES IN PATIENTS WITH NUMMULAR ECZEMA
Authors: Udzhukhu Vladislav Yu. , Korotkiy N. G , Davtyan E. V , Kubylinskiy A. A
Published: September 2020

Constant cellular and humoral immunity disorders promote the development of nummular eczema. Severe refractory cases of eczema represent a complex therapeutic problem. Increasingly eczema resistance to standard methods of therapy forces specialists to use systemic drugs with immunosuppressive action and a high risk of serious complications. Material and methods. The therapeutic possibilities and safety of the new domestic immunoactive agent L-isoleucyl-L-glutamyl-L-tryptophan sodium salt in patients with nummular eczema and its effect on the immune homeostasis were analyzed. The drug was included in complex treatment in 34 patients with nummular eczema. The comparison group composed 20 patients who received standard therapy. The highly sensitive methods for assessing the immune status: the cytokine system, the relative affinity of antibodies and the expression of Toll-like receptors (TLRs) are used. Results. 24 (70.6%) patients had a clinical cure and 9 (26.5%) patients had a significant improvement after L-isoleucyl-L-glutamyl-L-tryptophan sodium salt treatment. Only 1 (2.9%) patient had no effect from the therapy. There were no any side effects and complications in the course of the therapy. In the comparison group, clinical cure was achieved in 11 (55%) patients, the effect of the therapy was not observed in 2 (10%) patients. Conclusion. After the termination of the course of therapy, 15 (44.1%) patients had a clear tendency to normalize the affinity of immunoglobulins, The intensity of TLR4 expression was significantly reduced and did not differ from those in healthy donors. The use of this drug quickly allowed to stop the clinical manifestations of nummular eczema with the preservation of long-term remission, to normalize the processes of interleukin-dependent regulation of the immune response and nonspecific resistance. The advantage of the proposed method of treatment is the possibility of using in outpatient settings.
ANALYSIS OF THE INCIDENCE AND MAIN CLINICAL FORMS OF SYPHILIS IN SOME AREAS OF THE MOSCOW REGION AGAINST THE BACKGROUND OF MIGRATION FROM EPIDEMIOLOGICALLY DANGEROUS COUNTRIES
Authors: Fetisova Natalia V. , Snarskaya E. S
Published: September 2020

Purpose: to conduct a clinical and epidemiological analysis of the incidence of syphilis in the Moscow Region for the period from 2010 to 2017. Material and methods. Assessment of the incidence of various population groups and the manifestation of the epidemic process was carried out on the basis of an analysis of statistical data on the Moscow Region and statistical charts of patients. A comprehensive clinical examination of patients with syphilis was conducted to identify early signs of syphilitic infection and the presence of late forms of nervous system damage. Results. The analysis of the epidemic situation in Moscow region for the indicated observation period showed that the incidence of late forms of syphilis has increased. Conclusion. Analysis of the epidemic situation in the Moscow Region for the period 2010-2017 showed that the incidence of syphilis in the region’s population has increased, The incidence of asymptomatic neurosyphilis also has increased. The influx of migrants from epidemiologically dangerous countries and the availability of sex services support the consistently high level of incidence of syphilis in the Russian Federation.
HISTORY OF VITILIGO EXPERIMENTAL STUDY
Authors: Lomonosov Konstantin M. , Rem M. A , Gorb V. A
Published: September 2020

The history of the experimental study of vitiligo on animal models is studied. Effective analysis of any disease is not possible without conducting biomedical research on animal models. The models of both spontaneous and induced vitiligo in animals are described, which allows to study the etiology and pathogenesis of this disease in vivo, as well as to investigate the effectiveness of various drugs.
OVERVIEW OF MODERN STUDIES OF COMORBIDITY IN PSORIASIS
Authors: Pashinyan Albina G. , Dontsova E. V
Published: September 2020

Psoriasis is a multifactorial inflammatory skin disease associated with various medical conditions. The article presents an overview associations between psoriasis and ulcerative colitis, diabetes, chronic neuropathy, depressions, lymphomas, malignant processes, especially lymphoproliferation, metabolic syndrome. Patients with psoriasis, particularly if disease is severe, are at increased risk of cardiovascular diseases, such as hypertension, myocardial infarction, and stroke. Have examined the association between psoriasis and glomerulonephritis as well as chronic kidney disease. Factors influencing the course of psoriasis include age, stress, smoking, alcohol, a violation of diet, the presence of chronic obstructive pulmonary disease, sleep apnea, mental disorders The article presents an overview associations between psoriasis and metabolic syndrome. When a subject has three of the five listed criteria, a diagnosis of the metabolic syndrome can be made. The criteria listed include glucose intolerance presenting higher fasting glucose 6,1; increased waist circumference or abdominal obesity (≥ 102 cm for men and ≥ 88 cm for women); raised triglyceride levels ≥ 1.7 mmol/l; reduced high-density lipoprotein < 1.04 mmol/l for men and < 1.30 mmo/l for women; and elevated blood pressure 130/85 mmHg. In patients with psoriasis found a significantly increased prevalence and severity of coronary artery calcification.
The specific changes in the activity of the antioxidative system of blood under the influence of courses of treatment with the use of mineral water from the Pyatigorsk source modified by nano-scale particles of selenium (an experimental study)
Authors: Efimenko Natalia V. , Abramtsova A. V
Published: September 2020

The objective of the present study was to evaluate the influence of the courses of intake of Pyatigorsk spring water characterized by the level of mineralization up to 5.01 g / l (weakly acidic, containing sulfates, bicarbonates, chlorides, calcium, and sodium) modified by nano-scale particles of selenium. The experiments were carried out on 46 male Wistar rats allocated into 6 groups of 8 animals each (1 control group and 5 experimental groups). The animals of the former group were given native drinking mineral water during 21 days while those of the latter ones drank the same water modified by nano-scale particles of selenium added at two doses, either 40 mg / kg or 20 mg / kg. Some animals received water containing dissolved nanoparticles of selenium at the same doses. The parameters measured included the leukocyte blood profile, the level of glutathione peroxidase, and indicators of metabolic stress (aminotransferase and malone dialdehyde levels, i.e. modified oxidized low-density lipoproteins, total protein and glucose levels in blood). It was shown that the levels of malone dialdehyde and modified oxidized low-density lipoproteins did not change in the animals of experimental groups compared with those in the control group. It suggested resistance of lipids to free radical oxidation under the conditions of the course drinking of natural water and the water modified by nano-scale particles of selenium. Native mineral water proved to increase the level of glutathione in blood to above the control values in 50% of the test animals whereas mineral water modified by selenium nanoparticles caused a similar increase in 75% of the experimental animals regardless of the selenium concentration. It is concluded that the enhancement of the activity of the antioxidative system under effect of addition of the selenium nanoparticles into mineral water at the doses of 20mg/kg and 40mg/kg limits the production of organic hydroperoxides. The data obtained can be used to choose the optimal amount of selenium nanoparticles for the introduction into mineral water for the purpose of increasing its biological potential.
The evaluation of the effectiveness of structural resonance therapy in the patients with lupus erythematosus and comorbid pathology of the gastrointestinal tract
Authors: Levshin Roman Nikolaevich , Kotenko K. V , Kruglova L. S , Korchazhkina N. B
Published: September 2020

The authors report the results obtained during the combined application of various regimens of structural resonance therapy (SRT) for the treatment of 40 patients presenting with lupus erythematosus (LE) and comorbid pathology of the gastrointestinal tract. The use of this approach in the combination with the standard medicinal treatment made it possible to achieve clinical remission of the disease and to significantly improve the skin process in 100% of the patients as appears from the data on dynamics of the severity index of the cutaneous process. Simultaneously, the general health status of the patients was considerably improved. It is concluded that the proposed combined approach markedly increases the patients’ quality of life being responsible for a 87% reduction of the quality of the dermatology life quality index which allows to recommend this method for the wide application in the clinical practice for the management of the patients with the widespread forms of lupus erythematosus and comorbid pathology of the gastrointestinal tract.
THE USE OF DRINKING MINERAL WATERS FOR THE TREATMENT AND REHABILITATION: A MODERN VIEW OF THE PROBLEM
Authors: Kulikov A. G , Voronina Daria D.
Published: September 2020

The article covers the issues related to the use of mineral waters in clinical practice. It has been found that mineral waters, if chosen and prescribed appropriately for a given patient, help to restore regulation of gastric and pancreatic juices to the normal values seen in healthy individuals, to stimulate biliary formation and secretion, to exert the positive influence on the hormonal and neurohumoral regulation. Mineral waters help to improve different types of metabolic processes and immune regulation as well as to enhance the blood flow in kidneys and liver. The mineral waters are efficient for the treatment of the urinary system disorders, diabetes mellitus, obesity, and other pathologies, including those that are characterized by concomitant metabolic disorders. On the other hand, mineral waters are prescribed for or advised to be used by the patients not only by the doctors affiliated with the health resorts, but also by other healthcare practitioners who occasionally fail to be fully aware of the specific problems related to their clinical application. For this reason, the present article was designed to cover the main principles related to the prescription of mineral waters for the clinical use and elaborate the proper procedures that would serve as the guidelines on their application as well as to provide general information for the physicians of different specialty profiles on the availability of the extensive range of natural and spa mineral waters that originate from various regions of this country. The emphasis is placed on the filling of the expertise gaps related to the classification of mineral waters and their main properties that are believed their efficient clinical use.
THE TREATMENT OF HERNIAS OF INTERVERTEBRAL DISCS OF THE LUMBAR SPINE BY MULTIFREQUENCY FOCUSING SHOCK WAVE THERAPY
Authors: Ovcharenko Leonid M.
Published: September 2020

We have undertaken the clinical evaluation of the effectiveness of the new effective method for the conservative treatment of hernias of intervertebral discs of the lumbar spine by means of the multifrequency focusing shock wave therapy. The parameters of the exposure and the individual steps of the management of the patients with spinal hernias are described.
THE EARLY KNEADING OF THE RADIOCARPAL JOINT WITH A CLOSED FRACTURE OF THE DISTAL RADIUS METAEPIPHYSIS
Authors: Valeev Marat Mazgarovich , Biktasheva E. M
Published: September 2020

This paper presents a clinical case of the successful treatment of a patient with a closed Association of osteosynthesis type C fracture of the distal metaepiphysis of the left radius. The early three-week rehabilitation using kinesitherapy by the «Artromot H» device within 2 postoperative weeks made it possible to avoid the development of positional stiffness of the radiocarpal joint. Within 6 post-traumatic weeks the full range of motion of the joint and the patient’s working capacity were restored.
PHYSIOTHERAPY IN THE COMPLEX TREATMENT OF THE TEMPOROMANDIBULAR JOINT PAIN DYSFUNCTION SYNDROME IN PERSONS PROFESSIONALLY ENGAGED IN VOCAL
Authors: Volkov Alexander Grigorievich , Dikopova N. Zh , Kislitsyna A. V , Shishmareva A. L
Published: September 2020

Application in complex treatment of the temporomandibular joint pain dysfunction syndrome in vocalists infrared irradiation and ultrasonic treatment eliminates the pain and increased tone of the masticatory muscles in a short time, which increases the amplitude of movements of the mandible and the functional capabilities of the temporomandibular joint with increased professional workload. The proposed course of physiotherapy procedures allows for successful rehabilitation in a complex of therapeutic measures and to improve the effectiveness of treatment of the temporomandibular joint pain dysfunction syndrome, which is especially important for the quality of life of people involved in the vocals.
PHYSICAL REHABILITATION AFTER SURGICAL TREATMENT OF RUPTURE OF THE ROTATOR CUFF OF THE SHOULDER
Authors: Mikhalyova Alina Vladimirovna , Kulikov A. G , Makarova I. N
Published: September 2020

The examination and treatment of 62 patients operated on for damage to the rotator cuff of the shoulder and received basic therapy, including symptomatic medications and curative gymnastics according to the standard method were made. Patients of the main group in addition to basic treatment were given an exercise course with dynamic controlled muscle tension in the immobilization and postimmobilization period. It has been revealed that the inclusion of exercises with dynamic controlled muscle tension in the therapeutic complex has a more significant effect on the main clinical symptoms of the disease, the regeneration processes, and also contributes to an earlier restoration of impaired functions of the shoulder joint.
СOMPARATIVE EFFICACY OF TRANSCRANIAL ELECTROSTIMULATION AND INTRAVENOUS LASER BLOOD IRRADIATION IN TREATMENT OF CHRONIC DIFFUSE LIVER DISEASES
Authors: Skvortsov Vsevolod Vladimirovich , Tumarenko A. V
Published: September 2020

The article presents the results of an evaluation of the comparative efficacy of treatment for 198 patients with chronic diffuse liver diseases, which show that transcranial electrostimulation is generally comparable in effectiveness with the method of intravenous laser irradiation of blood, differing in non-invasiveness and lower cost.
THE EFFECT OF SELENIUM MODIFIED CARBON DIOXIDE MINERAL WATERS OF PYATIGORSK FIELD ON SOME SELENIUM DEPENDED SYSTEMS
Authors: Abramtsova Anna Viktorovna , Efimenko N. V , Kaysinova A. S , Polyakova L. V
Published: September 2020

The influence of course intake of the natural mineral water of the Pyatigorsk source, modified by selenium nanoparticles at a dosage of 40 μg/kg, on the level of thyroid hormones, insulin, cortisol and dehydroepiandrosterone, including depending on the method of drinking animals (free drinking and intragastric) was studied in rats. The histological structure of the thyroid gland during drinking with mineral water corresponded to that of healthy control animals, but in the group that received water intragastrically through the probe, the function of thyrocytes and levels of triiodothyronine and dehydroepiandrosterone in the blood were reduced. The courses of the mineral water modified by selenium nanoparticles, according to the data of multiple linear regression, contributed to the activation of the thyroid system.
BACKWARD WALKING AS A NEW TECHNIQUE FOR PHYSICAL REHABILITATION
Authors: Klemenov Aleksey Viktorovich
Published: September 2020

Backward locomotion (backward walking and running) is increasingly used in sports and medicine. Kinetic and kinematic analysis of backward walking showed its advantages over the usual method of movement that can be successfully used in the athletic training and for treatment and rehabilitation after various diseases. During sports training backward walking/running can be used as one of the methods of fitness to improve physical endurance. Backward walking leads to a more cardiovascular and respiratory load and a more significant aerobic and anaerobic capacity of the organism compared with forward walking at similar parameters of physical activity. Backward walking is associated with less overload on knee joints, it is also one of the few natural ways of strengthening the quadriceps. Backward walking is used to elaborate the correct pattern of gait in children with cerebral palsy, in persons with hemiplegia after stroke, in patients suffering from Parkinson’s disease and multiple sclerosis, in spinal cord injured patients. Regular backward walking trainings improve spatial-temporal parameters of walking and balance, increase muscle strength of the lower limbs in these diseases. There is an information about the application of backward walking exercises in diabetic foot syndrome in order to reduce a plantar pressure and in physical rehabilitation of postoperative patients. Tests with backward walking are used for diagnostic purposes - to assess the severity of impaired coordination and motor skills in post-stroke patients and in Parkinson’s disease, to identify the minimal walking impairment in persons with multiple sclerosis and for probability of falling prediction in elderly individuals and patients with dizziness.
TOWARDS THE QUESTION OF «DOSE» MOTOR REHABILITATION AFTER STROKE: REVIEW
Authors: Grokhovsky S. S , Kubryak Oleg Vitalievich
Published: September 2020

According to regulatory documents and published studies, the time in the hospital for rehabilitation after a stroke during one stage is 10-30 hours or more per patient. At the same time, a reliable assessment of the required volume of motor rehabilitation and motor training remains an actual and complex task, which requires special attention of researchers and consensus solutions in order to obtain clear justifications for choosing the type and mode of employment, and to improve the effectiveness of the measures taken.
INFLUENCE OF THE COMPLEX CORRECTION TECHNIQUE TO STRENGTH OF THE QUADRICEPS FEMORIS MUSCLE OF PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME
Authors: Prokhorova Elena Sergeevna , Ar’kov V. V , Makarova M. R
Published: September 2020

In 40 patients with patellofemoral pain syndrome, before and after the course of treatment, the strength indices of the hip muscles were studied by isokinetic dynamometry, as well as the severity of the pain syndrome in the knee joint and the lumbosacral spine according to the visual analogue scale. The patients of the main group (n = 20) used the technique of complex correction of the pelvic region and lower limb, which was mainly aimed at stabilizing the lumbosacral spine. Patients of the control group (n = 20) performed therapeutic gymnastics aimed at training the muscles of only the interested lower limb. The treatment was performed on an outpatient basis daily for 21 days. After the course of treatment in patients of the main group, the strengths of the quadriceps femoris were significantly higher (p < 0.05), and the degree of pain in the knee joint and lumbar spine was significantly lower (p < 0.05). The obtained data confirm the necessity and expediency of including exercises for stabilization of the lumbosacral spine in the rehabilitation program for patients with patellofemoral pain syndrome.
THE ROLE OF EARLY REHABILITATION AFTER CAROTID ENDARTERECTOMY IN ACUTE PERIOD OF ISCHEMIC STROKE
Authors: Polyakova Alexandra Viktorovna , Tokareva D. V , Zabirov S. Sh , Voznyuk I. A
Published: September 2020

The aim of our study was to evaluate the role of early rehabilitation of patients with ischemic stroke after carotid endarterectomy. Material and methods. We examined a group of 28 patients with atherosclerotic carotid stenosis who had CEA in an acute period of stroke and who started rehabilitation in the early period of stroke. Patients of the 1st group were admitted to rehabilitation in the early stages (within 21 days after the stroke), patients of the 2nd group - in the delayed period (more than 60 days after the stroke).The results of treatment were assessed on the NIHSS scale, Rankin scale, Rivermead mobility scale, spasticity was assessed on the Ashworth scale. Results. An analysis of the long-term results of surgical treatment convincingly showed its positive effect on the neurological and neuropsychological status of patients with the most favorable outcomes in performing early rehabilitation.
Work rehabilitation questionnaire (WORQ). Development of the russian version
Authors: Karapetian K. K. , Vasilchenko Elena Mikhailovna , Escorpizo R.
Published: September 2020

Cross-cultural adaptation of the Work Rehabilitation Questionnaire (WORQ) was performed. WORQ is a generic instrument for assessment of social and vocational status and can be applied in different populations. This paper includes Russian version of the Questionnaire and guidelines for filling in the questionnaire.
Peculiarities of training in rehabilitation of patients with Cerebral Palsy
Authors: Zyukov Ilya М.
Published: September 2020

In the article the features of training in rehabilitation of patients with cerebral palsy. On the basis of literature analyses the peculiarities of rehabilitation of children with cerebral palsy. Revealed that the majority of children with cerebral palsy face problems because they are associated with delayed development or abnormal development of the statokinetic reflexes, disorders of muscle tone, paresis. The goal of treatment and rehabilitation of children with cerebral palsy is to reduce the degree of disability, improving self-service capabilities, i.e. the maximum adjustment to daily life. Accordingly, the physical rehabilitation in a specialized clinic is important, because it improves physical condition contributes to effective correction of the functional deficiency of the locomotor apparatus, provides training cardiovascular and respiratory systems, leading to better activity of the child in learning activities and adaptation in society.
The approach to the rehabilitation of the patients presenting with central dysphagia on an individual basis
Authors: Sidyakina I. V , Voronova Mariya Viktorovna
Published: September 2020

Disorder of the swallowing act occurs in 25-50% of patients in the acutephase of stroke. The presence of dysphagia in a patient notonly can develop life-threatening complications, such as aspiration pneumonia, exhaustion and dehydration, but al so significantly reduces the quality of life of patients. Thus, the correction of thes wallowing act disorders after brain damage is a quite significant challenge for neurorehabilitation. For a long time logopedic correction remained the only method of rehabilitation inneurogenic dysphagia, and now different stimulation techniques such as surface and intra pharynx electro stimulation are widely used. Evaluation of swallowing by scintigraphy indicates that each patienth as a unique pattern of disorders of the swallowing act. Depending on which elongation phase of swallowing is essential, we have developed an individualized approach to there habilitation of patients with dysphagia, which improves the efficiency of there habilitation process.
Distant rehabilitation: the sources, current state-of-the-art, and further prospects
Authors: Snopkov Pavel Sergeevich , Lyadov K. V , Shapovalenko T. V , Sidyakina I. V
Published: September 2020

Medical rehabilitation is now a priority of the Russian Healthcare [Skvortsova V.I., 2012]. Rehabilitation centers are usually located in big cities and are not available for most patients. Therefore, one of the modern trends in the development of rehabilitation is a distantly controlled rehabilitation. We have developed a program of distant rehabilitation in Russia, based on our own achievements and experience of foreign colleagues. The article provides an overview of methods according to world literature studies. The survey shows that the problem of distant rehabilitation is relevant in our time, and requires additional clinical research and technological development.
THE THEORETICAL AND PRACTICAL ASPECTS OF APPLYING MEDICAL SOCIAL ON-LINE SERVICES IN MANAGEMENT OF REHABILITATION OF PATIENTS OF TRAUMATOLOGICAL ORTHOPEDICS PROFILE
Authors: Fedonnikov A. S , Andriyanova E. A , Grishechkina N. V , Cherhyshkova E. V
Published: September 2020

The issue of digital technologies implementation in practice of health care becomes one of the priorities in the conditions of resources deficiency. The digitalization of health care system is economically expedient as it allows achieving particular medical and social results without significant infrastructural investments. The on-line communication possesses significant potential in this regard. The digital health care using on-line communication democratizes access to medical services and allows to qualitatively remodel the existing model of interaction between patient and health care system. In the sociology of medicine, the sociology of rehabilitation is selected to investigate such issues as social and organizational context of rehabilitation, social orientation of medical care, role of health care personnel and other interested specialists. The article substantiates the efficiency of on-line communication in management of rehabilitation of patients as exemplified by the Monitoring and Feedback System designed and introduced in the Research Institute of Traumatology, Orthopedics and Neurosurgery of V.I. Razumovsky Saratov State Medical University.
THE METHODS OF STUDYING QUALITY OF LIFE OF PATIENTS SUFFERING OF CHRONIC DISEASES
Authors: Romanov S. V , Khudoshin N. A
Published: September 2020

The article considers problems of quality life analysis under evaluating effectiveness of treatment of chronic diseases. The conclusion is made that there is no unification of concept of «quality of life» and methods of its investigation, that complicates comparing results of different studies.
THE QUALITY OF LIFE OF PATIENTS AFTER TOTAL ENDOPROSTHESIS REPLACEMENT OF HIP JOINT: PUBLICATIONS REVIEW
Authors: Khudoshin N. A , Abaeva O. P , Romanov S. V
Published: September 2020

The main and generally accepted method of surgical treatment of arthrosis of hip joint is considered to be total arthroplasty. As a result, patient gets rid of pain, motor activity increases, more mobility and sociability are added. The surgical approaches (types of implants, operative approaches) and rehabilitation approaches (centers of specialized rehabilitation, outpatient rehabilitation clinics) are being improved. However, despite positive dynamics of improving quality of life, there is a group of patients of able-bodied age who have no satisfaction with surgery results.
THE ORGANIZATIONAL LEGAL ASPECTS OF QUALITY OF PALLIATIVE CARE OF PATIENTS OF ONCOLOGIC PROFILE AT THE ACTUAL STAGE
Authors: Ertel L. A
Published: September 2020

The article considers current regulatory framework governing provision of cancer palliative care and establishing the patients' rights. The main problems of implementation of legislation in this area are established, namely: problems of medical care quality, problems of legal regulation of voluntary informed consent, problems of implementation of right of patient to palliative care. It is noted that system of organizational and legal support of medical and social expertise in relation to oncologic patients in need of palliative care requires modernization, especially in terms of quality and availability of services provided by medical and social expertise institutions. The problem of personnel training for implementing procedure for interaction of medical organizations, social services is considered. The need for adjusting training programs to form necessary competencies in implementation of the Federal educational standards targeted to training qualified specialists to provide palliative care is emphasized.
THE MEDICAL SOCIOLOGICAL EVALUATION OF QUALITY OF LIFE OF PATIENTS WITH SENSORINEURAL DEAFNESS
Authors: Prisyazhnaya N. V , Zhuravlev A. S , Viatkina N. Yu
Published: September 2020

Health is the fundamental value of every individual, and its violations, especially those that are burdened by risk of disability, are the key factor of reducing quality of life of individual. The extent of prevalence of hearing impairment in population, accompanied by multiple problems in organization of social, professional and family life of patients, determines high social importance of the issue. The article presents results of medical and sociological study (focus group) of quality of life of patients with diagnosis "sensorineural hearing loss" (as exemplified by patients of Moscow multi-field hospital). The onset of disease, in addition to problems of physical well-being (pain, dizziness, disorientation, etc.) causes person sensorineural hearing loss reducing quality of life, and, above all, resulting in multiple communication problems at the level of everyday personal and social interaction. Despite the fact that the study participants believe that there is no negative attitude and stigma towards people with hearing loss among Russians, the respondents noted prevalence of general intolerant attitude towards disabled people. The widespread of sensorineural hearing loss among able-bodied population is accompanied with low level of public awareness of principles of prevention of hearing loss, the need for timely corresponding treatment, as well as peculiarities of interaction with people suffering hearing loss. The majority of respondents indicate high ability to work with adequate treatment and selection of hearing device and make adjustments to organization, and the support of family and working community.