bluuebunny/crossref_metadata_2025 huggingface dataset:
Experiences of increased food insecurity, economic and psychological distress during the COVID-19 pandemic among Supplemental Nutrition Assistance Program-enrolled food pantry clients
Authors: Higashi Robin T , Sood Anubha , Conrado Ana Belen , Shahan Kathryn L , Leonard Tammy , Pruitt Sandi L
Published: December 2021

Objective:

The COVID-19 pandemic initially doubled the rates of food insecurity across the USA and tripled rates among households with children. Despite the association among food insecurity, chronic disease and psychological distress, narratives depicting the experiences of already food insecure populations are notably underrepresented in the literature. The current study assessed the impact of COVID-19 on clients of a food pantry who were also enrolled in the Supplemental Nutrition Assistance Program (SNAP).

Design:

A qualitative study probing the effects of the pandemic on daily living, food needs, food buying and food insecurity. Interview transcripts were analysed using a combined deductive and inductive approach.

Setting:

Interviews were conducted via telephone between May and June of 2020.

Participants:

Equal numbers of English- and Spanish-speaking clients (n 40 total).

Results:

Three main findings emerged: (1) the pandemic increased economic distress, such as from job loss or increased utility bills due to sustained home occupancy and (2) the pandemic increased food needs, food prices and food shortages. In combination with economic stressors, this led to greater food insecurity; (3) increased economic stress and food insecurity contributed to increased psychological stress, such as from fear of infection, isolation and children being confined at home.

Conclusions:

Despite federal legislation and state and local programmes to alleviate food insecurity, COVID-19 exacerbated economic hardship, food insecurity and psychological distress among urban SNAP and food pantry clients. Additional research is needed to identify the most effective policies and programmes to ameliorate the short- and long-term health and economic inequities exacerbated by the pandemic.
Maternal perceptions and concerns about children’s weight status and diet quality: a study among Black immigrant families
Authors: Kengneson Cris-Carelle , Blanchet Rosanne , Sanou Dia , Batal Malek , Phillips Karen P , Giroux Isabelle
Published: December 2021

Objective:

To identify factors influencing Black immigrant mothers’ perceptions and concerns about child weight and to compare children’s diet quality according to these perceptions and concerns.

Design:

Mothers’ perceptions and concerns about child weight were assessed with sex-specific figure rating scales and the Child Feeding Questionnaire, respectively. Participants’ weights and heights were measured and characterised using WHO references. Children’s dietary intakes were estimated using a 24-h dietary recall. Children’s diet quality was evaluated using the relative proportion of their energy intake provided by ultra-processed products, which were identified with the NOVA classification. χ2 tests, multivariate logistic regressions and t tests were performed.

Setting:

Ottawa, Ontario, Canada.

Participants:

Black immigrant mothers of Sub-Saharan African and Caribbean origin (n 186) and their 6–12-year-old children.

Results:

Among mothers, 32·4 % perceived their child as having overweight while 48·4 % expressed concerns about child weight. Girls and children with overweight or obesity were significantly more likely to be perceived as having overweight by their mothers than boys and normal-weight children, respectively. Mothers of children living with obesity, but not overweight, were significantly more likely to be concerned about their child’s weight than mothers of normal-weight children. Children’s diet quality did not differ according to mothers’ perceptions and concerns.

Conclusions:

Children’s gender and weight status were major determinants of perceptions and concerns about child weight among Black immigrant mothers. Including knowledge about mothers’ perceptions and concerns about child weight will help nutrition professionals develop interventions tailored to specific family needs within the context of their cultural backgrounds.
The Geomagnetic Storm Time Response of the Mid Latitude Ionosphere During Solar Cycle 24
Authors: Tariku Yekoye Asmare
Published: December 2021

This paper mainly assesses the geomagnetic storm time response of the Africa, America, Asia and Europe mid latitude ionosphere in relation to the variability of the total electron content during solar cycle 24. This is carried out by considering the vertical total electron content (VTEC) data derived from the Global Positioning System (GPS), the recent International Reference Ionosphere (IRI 2016) and IRI‐Extended to the Plasmasphere (IRI‐Plas 2017) models in different geomagnetic storm days during solar cycle 24 (1 June 2013, 17 March 2015, and 28 May 2017). The effects of the 1 June 2013 and 17 March 2015 (2015 St. Patrick's Day) geomagnetic storms which resulted in intensification and fluctuation of the GPS VTEC variations were significantly enhanced in the European sector. On the other hand, the effect of the storm that occurred on 28 May 2017 was mostly pronounced in the American and Asian sectors. Both models are not able to adequately respond to the effects resulting from the geomagnetic storm. The VTEC calculated by the IRI models also generally decrease on most of the hours when the storm on option is applied during the main and recovery phases. Nevertheless, at the Asian station, the IRI‐Plas 2017 VTEC values tend to increase on most of the hours during the 2015 St. Patrick's Day storm. Moreover, as a result of enhancement of the VTEC, the satellite signal propagation during the positive geomagnetic storms is largely affected by the VTEC fluctuation.
Automated Detection of Antenna Malfunctions in Large‐N Interferometers: A Case Study With the Hydrogen Epoch of Reionization Array
Authors: Storer Dara , Dillon Joshua S. , Jacobs Daniel C. , Morales Miguel F. , Hazelton Bryna J. , Ewall‐Wice Aaron , Abdurashidova Zara , Aguirre James E. , Alexander Paul , Ali Zaki S. , Balfour Yanga , Beardsley Adam P. , Bernardi Gianni , Billings Tashalee S. , Bowman Judd D. , Bradley Richard F. , Bull Philip , Burba Jacob , Carey Steven , Carilli Chris L. , Cheng Carina , DeBoer David R. , de Lera Acedo Eloy , Dexter Matt , Dynes Scott , Ely John , Fagnoni Nicolas , Fritz Randall , Furlanetto Steven R. , Gale‐Sides Kingsley , Glendenning Brian , Gorthi Deepthi , Greig Bradley , Grobbelaar Jasper , Halday Ziyaad , Hewitt Jacqueline N. , Hickish Jack , Huang Tian , Josaitis Alec , Julius Austin , Kariseb MacCalvin , Kern Nicholas S. , Kerrigan Joshua , Kittiwisit Piyanat , Kohn Saul A. , Kolopanis Matthew , Lanman Adam , La Plante Paul , Liu Adrian , Loots Anita , MacMahon David , Malan Lourence , Malgas Cresshim , Martinot Zachary E. , Mesinger Andrei , Molewa Mathakane , Mosiane Tshegofalang , Murray Steven G. , Neben Abraham R. , Nikolic Bojan , Nunhokee Chuneeta Devi , Parsons Aaron R. , Pascua Robert , Patra Nipanjana , Pieterse Samantha , Pober Jonathan C. , Razavi‐Ghods Nima , Riley Daniel , Robnett James , Rosie Kathryn , Santos Mario G. , Sims Peter , Singh Saurabh , Smith Craig , Tan Jianrong , Thyagarajan Nithyanandan , Williams Peter K. G. , Zheng Haoxuan
Published: December 2021

We present a framework for identifying and flagging malfunctioning antennas in large radio interferometers. We outline two distinct categories of metrics designed to detect outliers along known failure modes of large arrays: cross‐correlation metrics, based on all antenna pairs, and auto‐correlation metrics, based solely on individual antennas. We define and motivate the statistical framework for all metrics used, and present tailored visualizations that aid us in clearly identifying new and existing systematics. We implement these techniques using data from 105 antennas in the Hydrogen Epoch of Reionization Array (HERA) as a case study. Finally, we provide a detailed algorithm for implementing these metrics as flagging tools on real data sets.
Circular RNA circRPPH1 promotes breast cancer progression via circRPPH1-miR-512-5p-STAT1 axis
Authors: Huang Yixiang , Zheng Wenfang , Ji Changle , Wang Xuehui , Yu Yunhe , Deng Xiaochong , Zhou Xiqian , Fang Lin
Published: December 2021

Breast cancer (BC) is one of the most fatal diseases among women all over the world. Non-coding RNAs including circular RNAs (circRNAs) have been reported to be involved in different aspects during tumorigenesis and progression. In this study, we aimed to explore the biological functions and underlying mechanism of circRPPH1 in BC. Candidate circRNAs were screened in dataset GSE101123 from Gene Expression Omnibus (GEO) database and a differentially expressed circRNA, circRPPH1, was discovered in BC. CircRPPH1 expression was higher in the cancerous tissue compared to paired adjacent tissue. Further in vitro and in vivo experiments indicated that circRPPH1 acted as an oncogene in BC. In addition, circRPPH1 was mainly localized in cytoplasm and played the role of miR-512-5p sponge. By sequestering miR-512-5p from the 3′-UTR of STAT1, circRPPH1 inhibited the suppressive role of miR-512-5p, stabilized STAT1 mRNA in BC and finally affected BC progression. In conclusion, these findings indicated that circRPPH1 acted as an oncogene and regulated BC progression via circRPPH1-miR-512-5p-STAT1 axis, which might provide a potential therapeutic target for BC treatment.
Automated vision screening of children using a mobile graphic device
Authors: Kane Steven A. , Gaspich Mark , Kane Julia , Weitzman Sarah A. , Hofeldt Albert
Published: December 2021

Background/Objective

Can measuring interocular brightness disparity, acuity, and colour vision classify children with amblyopia?

Subjects/Methods

Two hundred eight subjects (3–14 years) were recruited for a prospective, observational protocol to measure interocular brightness disparity, uniocular acuities with and without a pinhole, and colour vision using an iPad. Subjects looked through polarizing filters and chose the brighter of two spaceships to measure interocular brightness disparity. The differential brightness of image pairs was varied through a staircase algorithm until equal brightness was perceived. Acuities and colour vision were tested with tumbling Es and AO-HRR colour plates, respectively. Unilateral amblyopia was later confirmed in two subjects.

Results

Binocular brightness balance on the iPad detected amblyopes with 100% sensitivity and specificity. Using 20/30 as cutoff for normal acuity, 1 of the amblyopes was detected, and non-amblyopes were excluded by visual acuity pinhole testing. The mean difference between iPad and E-Chart visual acuities with pinhole was 0.02 logMAR with limits of agreement from −0.08 to +0.11 logMAR. iPad and printed plates Colour vision testing produced identical results. Testing times were brief and exit pleasure responses were positive. Mean and range testing times for Brightness Sense, Colour vision, and Visual Acuity were 32.7 s (range = 12–63 s), 52.8 min (range = 17–95 s), and 88.75 s (range = 41–188 s), respectively.

Conclusions

Interocular brightness disparity, acuity, and colour vision can be measured in children as young as 3 years old solely through playing a game on a mobile device. Interocular brightness disparity is a sensitive and specific method to detect unilateral amblyopia.
Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial
Authors: DeAngelo Daniel J. , Radia Deepti H. , George Tracy I. , Robinson William A. , Quiery Albert T. , Drummond Mark W. , Bose Prithviraj , Hexner Elizabeth O. , Winton Elliott F. , Horny Hans-Peter , Tugnait Meera , Schmidt-Kittler Oleg , Evans Erica K. , Lin Hui-Min , Mar Brenton G. , Verstovsek Srdan , Deininger Michael W. , Gotlib Jason
Published: December 2021

Advanced systemic mastocytosis (AdvSM) is a rare hematologic neoplasm driven by theKITD816V mutation and associated with poor survival. This phase 1 study (NCT02561988) evaluated avapritinib (BLU-285), a selective KIT D816V inhibitor, in patients with AdvSM. The primary endpoints were the maximum tolerated dose, recommended phase 2 dose and safety of avapritinib. Secondary endpoints included overall response rate and changes in measures of mast cell burden. Avapritinib was evaluated at doses of 30–400 mg once daily in 86 patients, 69 with centrally confirmed AdvSM. Maximum tolerated dose was not reached, and 200 mg and 300 mg daily were studied in dose-expansion cohorts. The most frequent adverse events observed were periorbital edema (69%), anemia (55%), diarrhea (45%), thrombocytopenia (44%) and nausea (44%). Intracranial bleeding occurred in 13% overall, but in only 1% of patients without severe thrombocytopenia (platelets <50 × 109/l). In 53 response-evaluable patients, the overall response rate was 75%. The complete remission rate was 36%. Avapritinib elicited ≥50% reductions in marrow mast cells and serum tryptase in 92% and 99% of patients, respectively. Avapritinib induced deep and durable responses, including molecular remission ofKITD816V in patients with AdvSM, and was well tolerated at the recommended phase 2 dose of 200 mg daily.
Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial
Authors: Gotlib Jason , Reiter Andreas , Radia Deepti H. , Deininger Michael W. , George Tracy I. , Panse Jens , Vannucchi Alessandro M. , Platzbecker Uwe , Alvarez-Twose Iván , Mital Andrzej , Hermine Olivier , Dybedal Ingunn , Hexner Elizabeth O. , Hicks Lisa K. , Span Lambert , Mesa Ruben , Bose Prithviraj , Pettit Kristen M. , Heaney Mark L. , Oh Stephen T. , Sen Jayita , Lin Hui-Min , Mar Brenton G. , DeAngelo Daniel J.
Published: December 2021

Advanced systemic mastocytosis (AdvSM) is a rare,KITD816V-driven hematologic neoplasm characterized by mast cell infiltration and shortened survival. We report the results of a prespecified interim analysis of an ongoing pivotal single-arm phase 2 trial (no.NCT03580655) of avapritinib, a potent, selective KIT D816V inhibitor administered primarily at a once-daily starting dose of 200 mg in patients with AdvSM (n = 62). The primary endpoint was overall response rate (ORR). Secondary endpoints included mean baseline change in AdvSM–Symptom Assessment Form Total Symptom Score and quality of life, time to response, duration of response, progression-free survival, overall survival, changes in measures of disease burden and safety. The primary endpoint was successfully met (P = 1.6 × 10-9), with an ORR of 75% (95% confidence interval 57–89) in 32 response-evaluable patients with AdvSM who had sufficient follow-up for response assessment, including 19% with complete remission with full or partial hematologic recovery. Reductions of ≥50% from baseline in serum tryptase (93%), bone marrow mast cells (88%) andKITD816V variant allele fraction (60%) were observed. The most frequent grade ≥3 adverse events were neutropenia (24%), thrombocytopenia (16%) and anemia (16%). Avapritinib demonstrated a high rate of clinical, morphological and molecular responses and was generally well tolerated in patients with AdvSM.
Predictors of changes in cerebral perfusion and oxygenation during obstructive sleep apnea
Authors: Zhang Zhongxing , Qi Ming , Hügli Gordana , Khatami Ramin
Published: December 2021

Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder. Severe OSAS defined as apnea–hypopnea index (AHI) ≥ 30/h is a risk factor for developing cerebro-cardiovascular diseases. The mechanisms of how repetitive sleep apneas/hypopneas damage cerebral hemodynamics are still not well understood. In this study, changes in blood volume (BV) and oxygen saturation (StO2) in the left forehead of 29 newly diagnosed severe OSAS patients were measured by frequency-domain near-infrared spectroscopy during an incremental continuous positive airway pressure (CPAP) titration protocol together with polysomnography. The coefficients of variation of BV (CV-BV) and the decreases of StO2 (de-StO2) of more than 2000 respiratory events were predicted using linear mixed-effect models, respectively. We found that longer events and apneas rather than hypopneas induce larger changes in CV-BV and stronger cerebral desaturation. Respiratory events occurring during higher baseline StO2 before their onsets, during rapid-eye-movement sleep and those associated with higher heart rate induce smaller changes in CV-BV and de-StO2. The stepwise increased CPAP pressures can attenuate these changes. These results suggest that in severe OSAS the length and the type of respiratory event rather than widely used AHI may be better parameters to indicate the severity of cerebral hemodynamic changes.
Higher mucosal antibody concentrations in women with genital tract inflammation
Authors: Sobia Parveen , Pillay Thevani , Liebenberg Lenine J. P. , Sivro Aida , Mansoor Leila E. , Osman Farzana , Passmore Jo-Ann S. , Abdool Karim Quarraisha , Abdool Karim Salim S. , Baxter Cheryl , McKinnon Lyle R. , Archary Derseree
Published: December 2021

Inflammatory cytokines augment humoral responses by stimulating antibody production and inducing class-switching. In women, genital inflammation (GI) significantly modifies HIV risk. However, the impact of GI on mucosal antibodies remains undefined. We investigated the impact of GI, pre-HIV infection, on antibody isotypes and IgG subclasses in the female genital tract. Immunoglobulin (Ig) isotypes, IgG subclasses and 48 cytokines were measured prior to HIV infection in cervicovaginal lavages (CVL) from 66 HIV seroconverters (cases) and 66 matched HIV-uninfected women (controls) enrolled in the CAPRISA 004 and 008 1% tenofovir gel trials. Pre-HIV infection, cases had significantly higher genital IgM (4.13; IQR, 4.04–4.19) compared to controls (4.06; IQR, 3.90–4.20;p = 0.042). More than one-quarter of cases (27%) had GI compared to just over one-tenth (12%) in controls. Significantly higher IgG1, IgG3, IgG4 and IgM (allp < 0.05) were found in women stratified for GI compared to women without. Adjusted linear mixed models showed several pro-inflammatory, chemotactic, growth factors, and adaptive cytokines significantly correlated with higher titers of IgM, IgA and IgG subclasses (p < 0.05). The strong and significant positive correlations between mucosal antibodies and markers of GI suggest that GI may impact mucosal antibody profiles. These findings require further investigation to establish a plausible biological link between the local inflammatory milieu and its consequence on these genital antibodies.
The states that hide in the shadows: the potential role of conical intersections in the ground state unimolecular decay of a Criegee intermediate
Authors: Marchetti Barbara , Esposito Vincent J. , Bush Rachel E. , Karsili Tolga N. V.
Published: December 2021

The ground state unimolecular decay of Criegee intermediates may potentially be influenced by conical intersections.
Radiation-induced transformations of acetaldehyde molecules at cryogenic temperatures: a matrix isolation study
Authors: Zasimov Pavel V. , Sanochkina Elizaveta V. , Feldman Vladimir I.
Published: December 2021

The mechanism of the radiation-induced transformations of isolated CH3CHO molecules in solid noble gas matrices at 5 K was proposed based on comprehensive FTIR studies.
Intrachain photophysics of a donor–acceptor copolymer
Authors: Nho Hak-Won , Park Won-Woo , Lee Byongkyu , Kim Seoyoung , Yang Changduk , Kwon Oh-Hoon
Published: December 2021

Ultrafast photophysics in the single chain of a PM6 is studied. The time evolution of locally excited (LE) and charge-transfer (CT)/separated (CS) states depends on the chain length highlighting effects of chain foldings on generating carriers.
Degradation of pesticides diazinon and diazoxon by phosphotriesterase: insight into divergent mechanisms from QM/MM and MD simulations
Authors: Fu Yuzhuang , Zhang Yuwei , Fan Fangfang , Wang Binju , Cao Zexing
Published: December 2021

Enzymatic degradation of pesticides diazinon (DIN) and diazoxon (DON) shows notable dependence on the substrate structure.
Cu@CuCl-visible light co-catalysed chlorination of C(sp3)–H bonds with MCln solution and photocatalytic serial reactor-based synthesis of benzyl chloride
Authors: Zhang Qi , Liu Shouxin , Tian Xia , Liu Yidong , Fan Shiming , Huang Baibiao , Whiting Andrew
Published: December 2021

A highly selective and sustainable chlorination of aliphatic C–Hs with inorganic chloride MCln as a chlorine source in a weak acidic water solution without strong oxidising agents under the co-catalysis of visible light is reported.
Signalling dynamics in embryonic development
Authors: Sonnen Katharina F. , Janda Claudia Y.
Published: December 2021

In multicellular organisms, cellular behaviour is tightly regulated to allow proper embryonic development and maintenance of adult tissue. A critical component in this control is the communication between cells via signalling pathways, as errors in intercellular communication can induce developmental defects or diseases such as cancer. It has become clear over the last years that signalling is not static but varies in activity over time. Feedback mechanisms present in every signalling pathway lead to diverse dynamic phenotypes, such as transient activation, signal ramping or oscillations, occurring in a cell type- and stage-dependent manner. In cells, such dynamics can exert various functions that allow organisms to develop in a robust and reproducible way. Here, we focus on Erk, Wnt and Notch signalling pathways, which are dynamic in several tissue types and organisms, including the periodic segmentation of vertebrate embryos, and are often dysregulated in cancer. We will discuss how biochemical processes influence their dynamics and how these impact on cellular behaviour within multicellular systems.
Making protons tag along with electrons
Authors: Guberman-Pfeffer Matthew J. , Malvankar Nikhil S.
Published: December 2021

Every living cell needs to get rid of leftover electrons when metabolism extracts energy through the oxidation of nutrients. Common soil microbes such as Geobacter sulfurreducens live in harsh environments that do not afford the luxury of soluble, ingestible electron acceptors like oxygen. Instead of resorting to fermentation, which requires the export of reduced compounds (e.g. ethanol or lactate derived from pyruvate) from the cell, these organisms have evolved a means to anaerobically respire by using nanowires to export electrons to extracellular acceptors in a process called extracellular electron transfer (EET) [ 1]. Since 2005, these nanowires were thought to be pili filaments [ 2]. But recent studies have revealed that nanowires are composed of multiheme cytochromes OmcS [ 3, 4] and OmcZ [ 5] whereas pili remain inside the cell during EET and are required for the secretion of nanowires [ 6]. However, how electrons are passed to these nanowires remains a mystery ( Figure 1A). Periplasmic cytochromes (Ppc) called PpcA-E could be doing the job, but only two of them (PpcA and PpcD) can couple electron/proton transfer — a necessary condition for energy generation. In a recent study, Salgueiro and co-workers selectively replaced an aromatic with an aliphatic residue to couple electron/proton transfer in PpcB and PpcE (Biochem. J. 2021, 478 (14): 2871–2887). This significant in vitro success of their protein engineering strategy may enable the optimization of bioenergetic machinery for bioenergy, biofuels, and bioelectronics applications.
Clinical significance and biological functions of chemokine CXCL3 in head and neck squamous cell carcinoma
Authors: Guan Jian , Weng Jinru , Ren Qiaosheng , Zhang Chunbin , Hu Liantao , Deng Wenjun , Lu Shizhen , Dong Xinyu , Li Weidong , Li Yue , Wang Weiqun
Published: December 2021

CXCL3 plays extensive roles in tumorigenesis in various types of human cancers through its roles in tumor cell differentiation, invasion, and migration. However, the mechanisms of CXCL3 in head and neck squamous cell carcinoma (HNSCC) remain unclear. In our study, multiple databases were used to explore the expression level, prognostic value, and related mechanisms of CXCL3 in human HNSCC through bioinformatic methods. We also performed further experiments in vivo and in vitro to evaluate the expression of CXCL3 in a human head and neck tissue microarray and the underlying effect mechanisms of CXCL3 on the tumor biology of HNSCC tumor cells. The result showed that the expression level of CXCL3 in patients with HNSCC was significantly higher as compared with that in normal tissues (P<0.05). Kaplan–Meier survival analysis demonstrated that patients with high CXCL3 expression had a lower overall survival rate (P=0.038). CXCL3 was further identified as an independent prognostic factor for HNSCC patients by Cox regression analysis, and GSEA exhibited that several signaling pathways including Apoptosis, Toll-like receptor, Nod-like receptor, Jak-STAT, and MAPK signaling pathways may be involved in the tumorigenesis of HNSCC. CAL27 cells overexpressing or HNSCC cells treated with exogenous CXCL3 exhibited enhanced cell malignant behaviors, whereas down-regulating CXCL3 expression resulted in decreased malignant behaviors in HSC4 cells. In addition, CXCL3 may affect the expression of several genes, including ERK1/2, Bcl-2, Bax, STAT3, and NF-κB. In summary, our bioinformatics and experiment findings effectively suggest the information of CXCL3 expression, roles, and the potential regulatory network in HNSCC.
Correlation Between Cone Resistance Values and Cohesion Values in Cohesive Soils (Case Study in Gunung Anyar District)
Authors: Estikhamah Fithri , Solin Dian Purnamawati
Published: December 2021

The physical and mechanical properties of the soil can be determined based on laboratory tests by testing soil samples obtained from field drilling. At one point it can be done simultaneously between SPT testing and drilling. Therefore, it can be known simultaneously the value of N-SPT with the physical and mechanical properties of the soil. The purpose of this study was to obtain a relationship between the cone resistance value (qc) obtained in the field and the cohesion value for cohesive soil types. This study uses primary data, and secondary data. The results of the correlation between the cone resistance value (qc) obtained in the field and the cohesion value for cohesive soil types show a strong correlation. This is indicated by the regression value which reaches a value of 0.75, which is 0.7809. The regression equation obtained is y = 0.0138x – 0.0063. The coefficient of the cone resistance value is 0.0138, indicating that every 1 constant increase in the cone resistance value variable will increase the cohesive value in the cohesive soil by 0.0138. The positive regression coefficient indicates that the higher the cone resistance value (qc), the higher the value of cohesion (c) for cohesive soils.
Modelling of Fat Oil and Grease (FOG) and Total Suspended Solid (TSS) Removal Rate on Dissolved Air Flotation Process Using Multiple Linear Regression
Authors: Hidayah Euis Nurul , Munir Syahrul
Published: December 2021

In the wastewater treatment process, floatation unit have been developed to remove particles or flocs that tend to be difficult to settle, such as fat oil and grease (FOG) and total suspended solids (TSS). Flotation is a unit operation that can separate the liquid phase or solid phase from the liquid phase, this can occur due to the presence of saturated air which is mixed so that it contains fine air bubbles that can help particles or flocs to be separated. This research was conducted by treating industrial area waste water using the flotation method with a pilot plant system. In order to work optimally, there are important parameters in the flotation process, such as debit and recirculation. This study aims to model the removal rate in FOG and TSS in the flotation process with multiple linear regression. From the modeling results, there are two models of FOG and TSS removal rate separately. R square value that obtained is for FOG and TSS removal rate is 0.678 and 0.214 consecutively.
Design of Automatic Chili and Tomato Sprinklers Based on Arduino Mega 2560
Authors: Putra Andika Adik , Pattipari Christin , Ponadi Acep , Muriani Muriani , Karim Johan , Jayadi Jayadi
Published: December 2021

Farmers generally do not know the amount of water needed by plants. Sometimes they also do not have enough time to water the plants regularly. Merauke Regency has a very strict climate between the rainy season and the dry season. During a prolonged summer can cause plants to experience drought due to lack of water. So, it is necessary to design an automatic plant sprinkler based on soil moisture around the plant. This study designed an automatic chili and tomato sprinkler based on Arduino Mega 2560 in Wasur II Village. The microcontroller used is Arduino mega 2560, soil moisture sensor YL-69, relay, water pump and sensor probe. 3 pairs of 20 cm soil moisture sensors will be connected in series, then plugged into the ground 15 cm deep. As a result, the tool performs watering (relay on) when the soil moisture in chili plants is below 75% and on tomato plants is below 70%. Furthermore, when the soil moisture in chili plants reaches 75.86%, the soil resistance value obtained is 34.58 ohms. Then when the soil moisture in tomato plants reaches 70.19%, the soil resistance value obtained is 42.70 ohms.
Design and Build a Smart Door Lock Using the Deep Learning Convolutional Neural Network Method
Authors: Joni Koko , Rahmawati Anita Ima , Sukri Hanifudin
Published: December 2021

The world is currently being hit by the COVID-19 virus. In this New Normal era, a rule is enforced that everyone must wear a mask wherever we are. Checking masks and body temperature is still done manually or by human observation, thus allowing for inaccuracies in observing and checking temperature. The problem occurred at Trunojoyo Madura University which still uses a manual mask and body temperature checking system. So, for accuracy and to reduce the risk of contracting officers. A tool was created to detect the mask and temperature automatically. In this study using a camera, temperature sensor MLX90614, and proximity sensor using Raspberry Pi. This research uses a machine learning system with the Deep Learning Convolutional Neural Network (CNN) Single Shot Detector (SSD) method. From this study, the results of mask detection obtained a success percentage of 93.4% and an error percentage of 6.6% from the entire test and obtained an average detection time of 2.63 seconds. And the average time of the whole system is 3.8 seconds. In this study, there was a delay during detection due to the heavy computational load on the system, so for further research, use a mini pc that has better performance.
Prototype Profile of Supercapactors with Activated Carbon/Fe3O4 Electrodes Natural Materials and Celgard Li-Ion Battery Separators
Authors: Rohmawati Lydia , Alfarisi Damini , Holisa SP Sitiv , Setyarsih Woro , Tukiran  , Subhan Ahmad
Published: December 2021

The electrode composition material in the supercapacitor affects the storage performance of the supercapacitor. In this study, the electrodes were made from coconut shell activated carbon and Fe3O4 from iron sand. To be used as electrodes, the two materials are mixed with PVDF and a solution of Dimethylacetamide at a temperature of 70°C; then, a coating process is carried out by layering the electrode material onto aluminium foil to obtain an electrode sheet. The coin cell assembling process was then carried out by arranging the electrode sheets and the Celgard Li-ion battery separator in the glove box and then tested for charge/discharge with a current density of 5-81 mA/g and cycle stability at a current of 20 mA/g. The study results show that the activated carbon/5 wt% Fe3O4 supercapacitor has the best capacitance value for charging at 8.03 F/g and discharging at 8.55 F/g at a current density of 5 mA/g. The activated carbon/5 wt% Fe3O4 supercapacitor has cycle stability of up to 200 cycles and can withstand up to 95% with a capacitance of 6.6 F/g.
Propagation Measurement on 2.5 mm NYAF Cable Using Load Matching and TDA
Authors: Ulum Miftachul , Purnamasari Dian Neipa , Ibadillah Achmad Fiqhi , Nahari Rosida Vivin
Published: December 2021

In this work, we propose measuring the propagation speed on the transmission medium in the form of a 2.5mm NYAF cable. The method used is load matching and time difference of arrival (TDA). The load matching method uses the same load as the characteristic impedance of the cable. While the TDA method measures two points on the cable with a capacitive load on the output side. From the results of the study, it was found that on the load impedance method, the average propagation speed on a 2.5mm NYAF cable is 1.9 × 108 m»s or 0.63 c. Meanwhile, in the time difference of arrival (TDA) method, the average propagation speed on a 2.5mm NYAF cable is 0.5 × 108 m»s or 0.17 c.
Web Planning Tower Base Transceiver Station Collective Mobile Telecommunications in Merauke City Based On Geographic Information Systems Using Mapinfo For The Next 10 Years
Authors: Corputy Roberto , Marsujitullah Marsujitullah , Zainuddin Zahir , Rezkyca Maulani Sirin
Published: December 2021

The purpose of this study is to develop a master plan for mapping joint cellular telecommunication BTS towers in accordance with the Regulation of the Minister of Communication and Information Number : 02/Per/M.Kominfo/03/2008 regarding the use of towers together. The method used to collect and process data and analyze the distribution zone using MapInfo software. The data collection was an existing BTS towers and population which calculating and find the need of towers in the future by calculating the number of residents, users, traffic, then processed to calculate the number of BTS and shared towers and through coverage the possible distribution zones of the towers described through MapInfo are determined. The results obtained are a master plan containing predictions of the need for BTS towers in 2029 as many as 43 BTS with each tower occupied by a maximum of 3 providers so as to minimize the occurrence of tower forests and an overview of the pattern regarding the distribution of shared towers using the MapInfo software.
Certainty Factor for Online Game Addiction Scale Diagnosis — A Case Study of Informatics Student, University of Khairun
Authors: Junaidi I , Mubarak A , Kapita S , Rosihan R , Siradjuddin HK
Published: December 2021

Online game addiction is the behavior of someone who wants to always play online games that lasts a long time and allows the individual concerned to not be able to control it so that it can have a negative impact that can have a negative impact on health and mental if too frequently play it. The aim of this study is to diagnose the online game addiction scale to students using the certainty factor algorithm. The level of online game addiction will be divided into three levels, namely: mild, moderate and severe addiction diagnoses. The calculation process starts from determining the weight value of each symptom and then determining the weight value of the user then calculating the weight value of each symptom with the user’s weight value using the certainty factor method so as to produce how large the percentage level of online game addiction. The results showed that from a number of processed data the diagnostic results were obtained 13% of students with mild addiction, 37% of students with moderate addiction, 50% of students with severe addiction.
Feature Optimization on Dual Leap Motion Controller for Indonesian Sign Language
Authors: Nugraha Syaiful , Rachmat  , Istanto Teddy , Prayitno Agus
Published: December 2021

Sign language is a language formed by a combination of finger, hand, body movements and facial expressions used by persons with disabilities such as deaf and speech impaired. One of these sign language recognitions is recognition using Leap Motion Controller (LMC) sensor technology. In addition to the sign language that is formed has diversity such as folded fingers, hidden fingers, indonesian sign forms also have characteristics and shapes that are almost similar to one another. The LMC sensor is not always able to recognize all forms of signs properly. In this study, optimization is proposed at the feature level where optimization aims to provide more detailed features and characteristics of each sign language formed. The stages of the process are designing the layout of the sensors, adding features and combining feature data from each sensor. The test of the feature optimization on this dual LMC sensor can provide an increase in the recognition accuracy of the given Indonesian sign language. The Indonesian sign language can be recognized well with an average accuracy of 87.24% and the optimization carried out is able to produce an increase in accuracy of up to 2.88%.
Impact of Mobile Learning using social media platform on Vocational Student’s Achievement Results
Authors: Mewengkang Alfrina , Liando Olivia E S
Published: December 2021

This research study was conducted to determine the effect of the mobile learning model using social media platforms on the learning outcomes of 2d and 3d animation techniques for students of class XI Multimedia at SMK Negeri 1 Tondano. This research uses experimental research in the form of Quasi Experimental Design or quasi-experimental and the research design used in this research is Post-Test Only Control Design. Before the treatment is given in each class, a pre-test is carried out first. After learning, using the Blendend Learning learning model for the experimental class and using conventional methods for the control class. After the learning process is complete, a post-test is carried out for each class. From the results of this post-test, the results obtained are the influence of the Learning Mobile Learning model on the learning outcomes of 2d and 3d Animation Engineering students of class XI Multimedia SMK Negeri 1 Tondano. The results showed that mobile learning had a positive effect on improving learning outcomes. Finally, the results show that mobile learning changes students’ study habits for the better.
Implementation of User Centered Design in User Experience Architecture for Geo-COVID mobile Applications
Authors: Anamisa Devie Rosa , Mufarroha Fifin Ayu , Oktaviyani Fauziah Reza , Angganata Nanda Prabu , Muhajir M. Dimas Arya
Published: December 2021

In Indonesia, there has been a significant increase in positive confirmed cases of Covid-19 caused by mutations in the Alpha, Beta and Delta variants. The uncontrolled spread has overwhelmed hospitals to treat Covid-19 patients. Hospitals are full of COVID-19 patients, making many people hesitate to check their health conditions. Geo-COVID is a one-stop application that aims to make it easier for the public to access health consultations, buy drugs online so as to reduce activities outside the home, PCR testing from home, transparency of information on the spread of COVID-19 cases, and sharing with families affected by COVID-19. The method used in the Geo-COVID architecture is User Centered Design. User Centered Design is a system design method that focuses on potential users. The stages used in achieving application goals in Geo-COVID design are Understanding the Context of Use, Determining User Needs, Design Solutions, Design Evaluation of User Needs. The target users of the Geo-COVID application are Indonesian people who are active outside the home and often interact with many individuals. The Geo-COVID application is oriented towards user experience which is limited to the Covid-19 distribution map in Indonesia, public health services, using a GUI interface type.
An Analysis of Physical and Environmental Security in Communication and Information Department Mojokerto
Authors: Maya Safitri Eristya , Aditya Ramadhani , Ridwandono Doddy , Dhian Satria Yudha Kartika
Published: December 2021

This study aims to provide an overview to the Communication and Information Department Mojokerto regarding the maturity level of physical and environmental security management at the agency, as well as to provide future recommendations. The results of research related to physical and environmental safety using the ISO 27002 standard, indicate that the level of physical and environmental security at the Communication and Information Department Mojokerto is still relatively low. Things that are still lacking include the lack of protection from external threats such as natural disasters, as well as the lack of care and maintenance of infrastructure. The maturity level of physical and environmental security control is 0.85 which is still at level 1 or Initial Ad Hoc from a maximum value of 5, which is at the Optimized level. It can be concluded that Communication and Information Department Mojokerto only knows that there are things that need attention but there is no standardization of the process. With this research, it is hoped that the Communication and Information Department Mojokerto can make improvements to improve physical and environmental security. In addition, it is also a consideration to obtain ISMS Certification with the ISO 27002 standard in the future.
Development of a Web-Based “Let's Donate” Fundraising Information System
Authors: Husni Husni , Putro Sigit Susanto , Dwi Putra Negara Yudha , Ulfa Yuana Nurma , Herawati Sri
Published: December 2021

This study aims to make it easier for donors who will donate without having to come to the place so that it is more effective and efficient. The development of this information system uses SDLC (Systems Development Life Cycle), which includes four stages, namely planning, analysis, design and implementation. By implementing this information system application, it is hoped that it will facilitate fundraising activities during both pandemic and non-pandemic periods. Fundraising is the process of collecting contributions from donors. Through data analysis, it is known that religious factors, the influence of campaigns and platform innovations have a positive effect, while the social spirit of the community has a negative effect. Overall, all factors are very important in influencing people to donate through online crowdfunding. The results of this study indicate that the factors of people's social life have a negative impact, because people believe that if someone has a high standard of social life, they are more likely to choose to provide assistance or donations directly rather than using the online system.
GIS Based Method for Flood Hazard Assesment in Kobe River Watershed - North Maluku Province
Authors: Nagu Nani , Lita A. Latif , Bebi H , Wahiddin Nurhalis
Published: December 2021

The objectives of this study are to mapping the hazard-prone area and to analyse the flood vulnerability index in Kobe Watershed, Central Halmahera District. In order to determine the optimal selection of weights for the factors that contribute to flood risk, GIS and multi-criteria decision analysis (MCDA) were used in conjunction with the application of the analytical hierarchy process (AHP) method to create the flood hazard map. The flood hazard map was generated by using selected hazard factors including land use, topography, slope, and rainfall pattern. The result shows that the Kobe River basin is a flood-prone area, with 77.46 percent of its land classified as less prone to flooding and 21.41 percent classified as flood-prone. However, only 21.41 percent of its land is classified as flood-prone. Only 1.13 percent of the land is protected from the danger of floods, compared to the whole country. The altitude factor is the most important element influencing flood susceptibility in Weda District, where the majority of the land (16.34 percent) is located at or below sea level, making it particularly vulnerable to flooding.
Utilization of RFID Technology in the Employee Mobility System of the Inspectorate Office of Merauke Regency
Authors: Putra Nasra Pratama , Loppies Stanly Hence Dolfi , Sayukti Titi Nalurita
Published: December 2021

The Inspectorate of Merauke Regency has a role as an internal supervisory agency for the implementation of government in Merauke Regency. Mobility in the office has not been supported by an entry and exit permit book for employees during working hours. The impact is a lack of employee attendance information. In addition, the process of calculating the percentage of active working time also experiences problems because it is done conventionally. To solve this problem, an employee mobility system was designed in the office by utilizing Radio Frequency Identification (RFID) technology. The system was built using the prototyping method. The design of mobility devices using a limited microcontroller in the form of a prototype. Presentation of data and information from the prototype recording is displayed on a website. The website is built using PHP and javascript programming languages. The results of the study led to a new innovation in monitoring the attendance of employees at the office during working hours by the Receptionist Department. The results of this study are also able to present the calculation of earning an allowance called Tunjangan Khusus Pengawasan Daerah (TKPD) for employees in the form of a percentage of mobility activity during active working hours.
Web-Based E-Teylor Sales Indormation System Design
Authors: Pramudita YD , Doni AF , Putro SS
Published: December 2021

The design of the E-Tailor sales information system is a web-based application as a means for employees or business owners to make it easier to order clothes online. Websites with this system can provide solutions to owners or tailors and consumers or ordering goods for smooth orders, transactions and completion of ordered goods on time and this will also make it easier for users to be able to order sewing items online without having to come to a tailor shop. In the design here it is also explained how a system will be built and run according to the manufacturing method carried out, for the design of the E-Tailor Information System is presented using UML (Unified Modeling Language). The testing method on the design of the e-tailor information system using the black box method only focuses on input and output that informs the suitability of the application developed with the specified specifications. The test results show that the success rate of the application runs well in accordance with the tests that have been carried out.
Relationship of Exogen Variables for Customer Use and Satisfaction of Delivery Services
Authors: Waluyo Minto , Winursito Yekti Condro , Islami Mega Cattleya Prameswari Annissaa , Sari Rizqi Novita , Waluyo Mohammad Rachman
Published: December 2021

The purpose of this paper is to determine the relationship of exogenous variables consisting of quality logistics service variables, brand image, and social media marketing on usage decisions and customer satisfaction. The shipping services studied specifically for domestic shipments consisted of J&T, JNE, TlKl, Wahana, SiCepat, ID Express, and Pos Indonesia using perception data through questionnaires. Respondents have at least used delivery services twice. Determination of the number of respondents using the maximum likelihood technique. The tool used in this research is Structural Equation Modeling. The results of this study indicate that the variables of logistics service quality and social media marketing have a positive and significant effect on usage decisions. The relationship between brand image and usage decisions cannot be proven because there is multicollinearity, which causes this variable to be excluded from the study. The equation of the relationship model of exogenous variables on the use and customer satisfaction of expedition services without using the brand image variable is as follows, Y2 = 0.371X1 + 0.482X3.