bluuebunny/crossref_metadata_2025 huggingface dataset:
Egy folyóirat adatait tartalmazó adatbázis relációs modelljének elkészítése
Authors: Hampel György
Published: February 2022

A Jelenkori társadalmi és gazdasági folyamatok című folyóiratban az első megjelenés óta összesen 895 szerzőtől 482 cikk jelent meg. Annak érdekében, hogy az eddig publikált, illetve a későbbiekben megjelenő számokban található információk hatékony módon kinyerhetők legyenek, egy adatbázis létrehozásának ötlete merült fel. Az adatbázis elkészítéséhez szükséges volt egy magas szintű koncepcionális modell megtervezése, majd az alapján a logikai adatmodell elkészítése. A folyóirat kapcsán ez az egyed-kapcsolat modell megtervezését, majd relációs modellé konvertálását jelentette; ez utóbbi ennek az írásnak a tárgya. Az egyed-kapcsolat modell 3 egyedhalmazt, 39 attribútumot és 3 kapcsolatot tartalmazott. A konvertálás során ebből született 10 táblázat az egyedek adatainak tárolására – összesen 22 különböző mezővel (oszloppal) – és további 3 táblázat az egyedhalmazok közötti kapcsolatok biztosítására. Az így kialakított modell relációs adatbáziskezelőben megvalósítható és alkalmas a folyóirattal kapcsolatos információs igények kiszolgálására.
Virtual reality-based cognitive stimulation using GRYDSEN software as a means to prevent age-related cognitive-mobility disorders – a pilot observational study
Authors: Podhorecka Marta , Andrzejczak Jarosław , Szrajber Rafał , Lacko Jan , Lipiński Piotr
Published: February 2022

The human aging process is associated with systematic deterioration of cognitive and motor performance. Age-related deficits in motor skills and symptoms of cognitive decline, such as memory, attention and executive functioning problems, are major contributors to a loss of functional independence and reduced quality of life of the elderly. The virtual reality system presented can be used as an aid for effective training of those skills. The use of virtual reality training for therapeutic purposes is promising – not only does it provide encouraging medical and psychological effects but it may also be considered as an interesting leisure activity for seniors. The paper presents a pilot study which aims to qualitatively assess the usefulness of a VR technology-based solution for training cognitive and motor functions. The pre-test phase of the study was conducted on 9 subjects aged 62-81 (M = 71.66; SD = 7.00), who were asked to evaluate the performed tasks in terms of novelty and attractiveness. All subjects completed the pilot study. The SUS result was 55.56 (SD = 9.90), which is a marginal result. However, the UEQ result showed that all aspects of the game were reported as satisfactory. The pilot studies show that VR is well tolerated by the elderly. As demonstrated by the results, the system has moderate utility, but may be a promising solution for training cognitive-motor skills.
In silico analysis of the interaction of Syntaxin-18, a putative receptor of
Peregrinus maidis (Ashmead) (Hemiptera: Delphacidae) with Maize mosaic virus glycoprotein
Authors: Alviar Karen , Clemente Apel Jae , Whitfield Anna
Published: February 2022

The corn planthopper,
Peregrinus maidis, is a widely distributed insect pest which serve as vector of two plant pathogenic viruses, Maize mosaic virus (MMV) and Maize stripe virus (MStV). It transmits the viruses in a persistent, circulative, and propagative manner. MMV is an alphanucleorhabdovirus with a negative-sense, single-stranded (ss) RNA unsegmented genome. Previous work using the membrane-based yeast two hybrid system on this pathosystem identified potential receptors for MMV. One identified insect vector protein is Syntaxin-18 (PmSTX18) which belongs to the SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) family of proteins. SNAREs play major roles in the final stage of the docking and the subsequent fusion of diverse vesicle-mediated transport events. In this work, in silico analysis of the interaction of MMV glycoprotein (MMV G) and PmSTX18 was performed. Functional annotation of PmSTX18 and MMV G was done to develop a reliable model for PmSTX18—MMV G interaction. Analysis and protein-protein interaction (PPI) prediction used sequence-based and structure-based approaches. Results showed that the four best predicted docked complexes have 45, 42, 22 and 27 amino acid interacting residues with binding affinities (change in Gibbs free energy, ΔG) of -57.73, -57.05, -52.55, and -51.69, respectively, suggesting strong interactions. This is the first in silico analysis performed for the interaction on a putative receptor of
P. maidis and MMV G. The results of the PPI prediction provide novel information for studying the role of STX18 in the transport, docking and fusion events of the virus in the insect vector host.
Scholars and Literati at the University of Cracow (1364–1800)
Authors: De la Croix David , Spolverini Gaia
Published: February 2022

This note is a summary description of the set of scholars and literati who taught at the University of Cracow (Kraków) from its inception in 1364 to the eve of the Industrial Revolution (1800).
Gestión del conocimiento, economías creativas e innovación suave*. Relaciones interdisciplinarias para los estudios corporales
Authors: Suárez Arteaga Mónica Cecilia
Published: February 2022

La sociedad del siglo XXI exige niveles educativos cada vez más altos, el conocimiento profundo de un tema o de un contexto social, científico y tecnológico se presenta como una necesidad laboral. Para el incremento en la formación se recurre a las universidades que propician trabajos de grado con investigaciones que implican esfuerzos en diversos aspectos humanos. Sin embargo, el acceso a recursos para la investigación en Colombia es reducido y la inversión pública y privada en investigación es escasa. En el artículo se presenta un panorama legislativo actual y comparado con América Latina, así como estrategias reflexivas alrededor de la gestión del conocimiento y las relaciones entre la academia y la sociedad como contribución a la mesa 5: Practicas estéticas, economías creativas, biopolítica, innovación y creatividad social, en el marco del II Encuentro Nacional de Investigación-Creación sobre el Cuerpo: El Giro Corporal, Prácticas Corporales para la Paz, la Re-Existencia y la Reconciliación Nacional (Colombia, 2018), cuya ponencia lleva el mismo título. El propósito del artículo es ampliar la mirada de la situación actual de Colombia en torno a la gestión política de la investigación, y proponer tres conceptos articuladores que son la innovación suave, la interdisciplinariedad y las economías relacionadas con la creatividad, que motiven a los investigadores a hacer un salto articulador entre la academia y el contexto social, con miras a la búsqueda de sostenibilidad a un plazo mayor y entendiendo que la investigación puede transformarse en acciones productivas para el país y que el discurso y los conceptos sobre el cuerpo pueden traspasar las barreras tradicionales. De esta forma, pretende acercarse al eje temático que responde a la pregunta: ¿Cuáles son los marcos institucionales que posibilitan la generación de nuevos modos de organización y gestión de las prácticas estéticas en contextos locales?, visibilizando un panorama nacional y proponiendo herramientas para el fortalecimiento local.
Clinical Significance of Detection of Human Papilloma Virus DNA and E6/E7 mRNA for Cervical Cancer Patients
Authors: Yu Tingting , Wang Chunyan
Published: February 2022

This study aimed to explore the clinical significance of detection of human papillomavirus (HPV) DNA and E6/E7 mRNA for cervical cancer patients. For this purpose, a total of 300 patients with cervical lesions who performed the colposcopy examination for the cervix between January 2018 and January 2020 were divided into three groups according to the level of cervical intraepithelial neoplasia (CIN): Low-level group (Group A, n = 101), high-level group (Group B, n = 149), cervical cancer group (Group C, n = 50) and gynecological inflammation group (Group D, n = 60). Tissue samples were collected from subjects above to perform the immunohistochemistry for E6/E7 protein and detection of HPV DNA and HPV E6/E7 mRNA. The results showed that HPV DNA copies and the positive rates of protein, DNA and mRNA of HPV E6/E7 in Groups A, B and C were significantly higher than those in Group D (all P<0.05), while no significant difference was identified in the comparison of the positive rate and copies of DNA among Group A, B and C (P> 0.05); in the Group A, B and C, patients had a higher positive rate of E6/E7 mRNA than those in the Group D (P<0.05), while in the Group B and C, the positive rate and copies of mRNA of HPV E6/E7 and HPV E6/E7 proteins were all higher than those in the Group A (P<0.05). In addition, the specificity of HPV E6/E7 mRNA was inferior to HPV DNA in the detection of the low-level intraepithelial neoplasia, but it performed better in the detection of the high-level intraepithelial neoplasia and cervical cancer. In general, HPV E6/E7 mRNA shows promising value in the detection of the development and progression of cervical cancer.
Efficacy of felodipine and enalapril in the treatment of essential hypertension with coronary artery disease and the effect on levels of Salusin-β, Apelin, and PON1 gene expression in patients
Authors: Zhang Wanyi , Zhang Jun , Jin Feng , Zhou Heng
Published: February 2022

This study aimed to analyze the effect of felodipine combined with enalapril in the treatment of patients with essential hypertension and coronary artery disease. Also, the effect of these medicines was evaluated on the peripheral blood Salusin-β, Apelin levels, and PON1 gene expression. For this purpose, 110 patients with essential hypertension combined with coronary heart disease, admitted to the hospital from January 2019 to January 2021, were selected and randomly divided into two groups. The control group was given felodipine treatment alone, and the study group was treated with combined application of felodipine and enalapril. The treatment effect, peripheral blood Salusin-β, Apelin, PON1 gene expression, and the safety of medication were compared between the two groups. The results showed that the post-treatment systolic blood pressure in the study group was 119.77 ± 5.23 mm Hg and diastolic blood pressure was 86.84 ± 5.42 mm Hg, both of which were significantly lower than those in the control group (127.81 ± 6.92 mm Hg and 95.13 ± 6.08 mm Hg), with statistically significant differences (p<0.05). The effective rates of the study group and the control group were 92.73% and 74.54% respectively, with statistically significant differences (P<0.05). The post-treatment peripheral blood Salusin-βlevel in the study group was 3.77±0.53mmol/L, and Apelin was 1.94±0.58μg/L, with statistically significant differences compared to the control group (P<0.05). The PON1 gene expression in the study group was higher than those in the control group after treatment (P<0.05). Also, the results showed that there was no statistical difference in adverse reactions between the two groups (P>0.05). According to these results, the combination of felodipine and enalapril in patients with essential hypertension combined with coronary artery disease can effectively lower the patients' blood pressure and improve their peripheral blood Salusin-β, Apelin levels, and PON1 gene expression, thus enhancing the patients' therapeutic effect with few adverse effects and high safety.
Evaluating the effect of methotrexate on the rate of renal fibrosis by elastography and fibrosis-related gene expression
Authors: Wang ZiFan , Ab Hamid Suzana , Jiang YanSheng , Shang XiaoBin , Fu Zhuo , Zhao QingJiang , Ab Hamid Suzana
Published: February 2022

Methotrexate is mainly used to treat diseases such as rheumatoid arthritis (RA), but its potential for nephrotoxicity has always been a significant concern on the use of this medication. This study aimed to determine the rate of renal fibrosis using transient elastography and its relationship with cumulative dose and duration of drug use in patients with rheumatoid arthritis treated with methotrexate. TGFβ gene expression was also assessed for further evaluation. Patients with rheumatoid arthritis who received methotrexate for more than six months were included. Renal fibrosis was determined by measuring the stiffness of the kidney by elastography (FiberScan Device). RA patients were divided into two groups based on kidney stiffness measurement with and without renal fibrosis, and demographic, clinical, and biochemical parameters were compared to investigate the relationship between cumulative dose and duration of methotrexate treatment and renal fibrosis. Also, in this study, 50 controls (healthy people) and 50 cases (RA patients) were used to evaluate the expression of the TGFβ gene by real-time PCR method. The existence of kidney fibrosis was observed in 10 patients. There was no significant relationship between renal fibrosis and the cumulative dose (P = 0.21) and duration of methotrexate (P = 0.30). Multivariate regression analysis showed that the chances of developing renal fibrosis in patients increase with increasing serum ALT levels (P = 0.01). The results of the TGFβ gene expression showed that the expression of this gene in the group of RA patients with fibrosis was higher than the control group (healthy people) and the group of RA patients without fibrosis (P <0.01). These results showed that evaluation of renal fibrosis by elastography method is recommended for scanning RA patients while they are being treated with methotrexate, which is also confirmed by the results of the fibrosis-related-gene expression.
Uninformed Bidding in Sequential Auctions
Authors: Lorenzon Emmanuel
Published: February 2022

We consider a private-value auction with one-sided incomplete information in which two objects are sold in a sequence of two second-price auctions. The buyers have multiunit demand and are asymmetrically informed at the ex ante stage of the game. One buyer perfectly knows his type, and the other buyer is uninformed about her own type. We consider interim information acquisition by the uninformed buyer and derive an asymmetric equilibrium that is shown to produce a declining price sequence across both sales. The supermartingale property of the price sequence stems from the uninformed buyer’s incentives to gather private information, which leads to aggressive bidding in the first-stage auction.
Detecting and mapping the ‘ephemeral’: magnetometric survey of a Pastoral Neolithic settlement at Luxmanda, Tanzania
Authors: Fitton Tom , Contreras Daniel A. , Gidna Agness O. , Mabulla Audax Z.P. , Prendergast Mary E. , Grillo Katherine M.
Published: February 2022

Common assumptions about the ephemeral archaeological signature of pastoralist settlements have limited the application of geophysical techniques in the investigation of past herding societies. Here, the authors present a geophysical survey of Luxmanda, Tanzania, the largest-known settlement documented for the Pastoral Neolithic era in eastern Africa (c. 5000–1200 BP). The results demonstrate the value and potential of fluxgate gradiometry for the identification of magnetic anomalies relating to archaeological features, at a category of site where evidence for habitation was long thought to be undetectable. The study provides comparative data to enable archaeologists to identify loci for future investigations of mobile populations in eastern Africa and elsewhere.
A genre analysis of master dissertation abstracts written by English native speakers and Tunisian EFL learners: Pedagogical considerations
Authors: Hamdi Sondes
Published: February 2022

Despite the growing interest in genre analysis, on the one hand, and the continuous concern with academic writing, on the other, very little has been done on the move structure of abstracts in Linguistics Master dissertations written by native speakers and non-native speakers of English (Al-Khasawneh, 2017). In the same vein, no single cross-linguistic study has investigated variations in the move structure of abstracts in dissertations written by English native speakers and Tunisian EFL learners. This paper is a response to this need. It purports to analyze the move structure of abstracts in Linguistics MA dissertations written by English native speakers and Tunisian EFL learners, within the theoretical framework of Hyland’s five-move model (2000). Twelve abstracts were selected for this study: Six abstracts were written by Tunisian EFL MA students at the Institut Supérieur des Langues à Tunis (ISLT, Tunisia) and six abstracts were written by English native speakers. The native speakers’ abstracts were randomly chosen from the Brigham Young University website for Linguistics Theses and Dissertations. The EFL learners’ abstracts were randomly chosen from the ISLT library. The findings suggest that the Purpose move, the Method use and the Product move are frequent in both corpora. However, only one English abstract in 6 contains the Conclusion move, whereas 4 EFL abstracts in 6 contain the Conclusion move. Both corpora contain the Introduction move, with equal frequency (4 in 6 for both corpora). Pedagogical considerations are highlighted for EFL teachers in order to ensure an efficient abstract teaching. It is argued that this study represents a contribution to the field of academic writing and genre analysis.
Brief exposure of neonatal testis cells to EGF or GDNF alters the regenerated tissue
Authors: Awang-Junaidi Awang Hazmi , Fayaz Mohammad Amin , Goldstein Savannah , Honaramooz Ali
Published: February 2022

We have previously shown that implantation of testis cell aggregates under the back skin of immunodeficient mice results in de novo regeneration of testis tissue. We used this unique model to investigate the effects of epidermal growth factor (EGF) and glial-derived neurotrophic factor (GDNF) on testis cord development. Neonatal piglet testis cells were briefly (<1 hr) exposed to either low (L: 0.02 μg/mL) or high (H: 2 μg/mL) doses of EGF, GDNF, or vehicle (Control), before implantation in recipient mice. Randomly selected implants were removed from each mouse at 1, 2, 4, and 8 wk post-implantation. GDNF-L implants showed increased testis cord development over time and EGF-L implants had increased cross-sectional area. The ratio of regular cords decreased over time in EGF-H and GDNF-H implants and was replaced by a higher ratio of irregular cords in GDNF-H. EGF-L and GDNF-H implants were quickest to display rete testis-like structures. Overall, the lower dose of each growth factor was more effective than its higher dose in improving the implantation outcomes. This is the first comprehensive assessment of these key growth factors on de novo formation (regeneration) of testis tissue.
Parental Leave for Residents and Pediatric Training Programs
Authors: Takagishi Jennifer , Garagozlo Katiana
Published: February 2022

Residency and fellowship are unique occupational time periods for many early career physicians, generally consisting of long duty hours. Many early career physicians have or are in the process of building their families during this time period. The literature suggests many medical and psychosocial benefits of protected parental leave for both parents and children, which necessitates parental leaves of absence. The Institutional Requirements of the Accreditation Council for Graduate Medical Education require training programs to provide written policies regarding leaves of absence, including parental leave, and these policies must comply with current legislation such as the Family Medical Leave Act. The length of leave has considerable variability among residency programs. This policy statement aims to navigate and outline the challenges of parental leave policies in training programs and to put forth recommendations to protect trainees and their families. The definition of families should also be expanded to include all types of families.
The influence of health-improving fitness classes on the degree of fat deposition in women of the second mature age
Authors: Podrihalo Olha , Jagiełło Władysław , Podrigalo Leonid , Iermakov Sergii , Yermakova Tetiana
Published: February 2022

Background and Study Aim. Purpose of the research: analysis of the influence of health-improving fitness classes of various orientations on the degree of fat deposition in women of the second mature age.
Material and Methods. Participants: group 1 – 40 women, (43.33 ± 0.93) years, group 2 – 25 women, (44.40 ± 0.93) years. The participants trained for 8 months, three times a week for 1 hour. Group 1 – classes in dance aerobics (Monday), strength fitness (Wednesday) and stretching (Friday). Group 2 – stretching only. Before the start and after the end of the program, the body weight and length were determined, the degree of fat deposition using a calipermeter at 17 points, the body mass index was calculated.
Results. In group 1, there was a significant decrease in body weight, BMI, a decrease in the thickness of skin and fat folds at all points. In group 2, a significant decrease in body weight, BMI, a decrease in the thickness of folds at 13 points in 60-96% of participants was established. At the end of the study, group 1 had a smaller size of the folds of the thighs and left forearm compared to group 2. Regular exercise leads to a decrease in body weight BMI, a decrease in body fat. Complex classes have a more pronounced effect compared to stretching. This type of training is more effective in terms of the dynamics of the criteria used and the number of participants with the established changes. The sessions provided an increase in the number of persons with a normal BMI and a decrease in the number of obese participants.
Conclusions. The applied indicators and methods can be recommended for use in health monitoring in health fitness.
Analisis Dampak Penambangan Timah di Laut Terhadap Ekosistem Laut dan Pendapatan Nelayan Desa Tanjung Binga
Authors: Jihan Dewi , Yuniarti Fiki Rizkita , Monalisa Jessica Thalia , Panjaitan Putri Maritho , Aprila Milenia , Khasanah Uswatun , Meliala Yudhea Christian , Ningrum Yusfiana
Published: February 2022

Tujuan penelitian ini adalah untuk mengetahui dampak penambangan timah di laut terhadap ekosistem laut di Bangka Belitung, pendapatan nelayan setempat, dan untuk mengetahui kebijakan yang telah ditetapkan, serta strategi yang tepat untuk masing-masing pemangku kebijakan. Analisis dengan melakukan survei deskriptif yang bersifat studi kasus, melalui wawancara terhadap stakeholder (stakehdolder analysis) dan kuisioner, yang menjadi fokus peneliti secara geografis adalah Desa Nelayan Tanjung Binga, Provinsi Bangka Belitung. Adapun metode analisis yang digunakan adalah analisis statistik deskriptif dengan pendekatan fenomenologi dan untuk mengetahui peranan pemangku kebijakan secara indeks, peneliti menggunakan software ATLAS.Ti. Hasilnya menunjukkan bahwa valuasi ekonomi perikanan tangkap di Desa Tanjung Binga, Kabupaten Belitung tahun 2019 adalah sebesar Rp 5.408.296.184.045,63 / tahun. Sedangkan, dari hasil wawancara terhadap lima stakeholder ditemukan informasi bahwa, baik perizinan maupun aktivitas penambangan sudah sesuai dengan SOP yang berlaku beserta pertanggungjawaban melalui penyaluran Corporate Social Responsibility (CSR).
Una aproximación a la cuestión de la «continuatio naturae» en el pensamiento de Leonardo Polo
Authors: Rodríguez-Soto Ana
Published: February 2022

Dice Polo que el ser humano es un espíritu en el tiempo, y ello se manifiesta también en el cuerpo. Por eso, las explicaciones que nos ofrece la biología evolucionista sobre nuestra realidad vital no son completas si no tienen en cuenta su dualidad con lo superior. En este trabajo pretendemos profundizar en la idea de que el hombre no se finaliza en la especie, sino que la trasciende; en esto consiste el concepto de continuatio naturae.
The curriculum tracker: A tool to improve curriculum coverage or just a tick-box exercise?
Authors: Mkhwanazi T , Ngcobo AZ , Ngema S , Bansilal S
Published: February 2022

Research on teacher professional development generally states that teachers do not take new innovations on board easily. The study reported on here focused on the uptake of a curriculum tracker tool designed to improve curriculum coverage by mathematics teachers. The tool formed part of the Jika iMfundo (JiM) programme launched by the KwaZulu-Natal Department of Education and a partner organisation. The purpose of this study was to explore the extent to which secondary mathematics teachers and heads of department (HoDs) used the tools for their intended purposes. The study was carried out with teachers and department heads from 14 schools located in 2 districts of KwaZulu-Natal. Data were generated by 21 interviews, supplemented by secondary data sourced from responses to previous surveys conducted by JiM. The findings show that most teachers considered the tool as a tick-box activity, instead of using it to guide their planning in a meaningful manner. Furthermore, there was misalignment between planning undertaken by the provincial education department and JiM. It is crucial that teachers on the ground are consulted first in order to jointly identify how certain problems can be addressed before any professional development activity is implemented.
Telehealth consultations in cardio-oncology
Authors: Potievskaya V. I. , Kononova E. V. , Shaputko N. V. , Raushkin D. A. , Gameeva E. V. , Alekseeva G. S. , Kaprin A. D.
Published: February 2022

Aim. To evaluate the role of a cardiologist in telehealth counseling of cancer patients at the federal oncology center.

Material and methods. This retrospective study was conducted based on the materials of 215 telehealth consultations on cardiooncology, performed in the period from January 2019 to September 2021. Data on referrals to a cardiologist (cardio-oncologist) from various Russian regions and consultants’ answers were analyzed, taking into account the following data: region, sex, age of a patient, cancer type, stage, participation of other consultants, type of cardiovascular disease, the need for additional information and features of treatment  — surgery, chemotherapy, radiation therapy. Risk was stratified based on a checklist including the main risk factors for cardiotoxicity. The recommendations of consultants for monitoring patients, as well as drug therapy prescriptions, were analyzed.

Results. The most common cancer sites in patients referred for telehealth consultations on cardio-oncology were lungs, larynx and trachea, colon and rectum, kidneys and bladder, ovaries and uterus, and stomach. Cardiologists consulted together with oncologists  — surgeons, medical oncologists, as well as anesthesiologists and radiation oncologists. The most common cardiovascular diseases were hypertension  — 80,9% of patients, heart failure  — 60%, arrhythmias — 41,6% and coronary heart disease — 37,7%. From 71 to 80,3%, 15,6-21% and 3,9-7,8% of patients had preserved, mid-range and reduced left ventricular ejection fraction. In 47,6-66,7% of cases, consultants required additional information. Based on risk stratification of cardiotoxicity of anticancer treatment, 118 (81,9%) patients out of 144 were classified as high and very high risk. Most patients were recommended cardioprotective therapy, which most often included angiotensin-converting enzyme inhibitors/angiotensin receptor blockers  — 43,1-53,1%, beta-blockers  — 44,8-58,6%, and statins  — 22,4-38,3%. An algorithm for creating a request for a cardio-oncology telehealth consultation has been developed.

Conclusion. The important role of cardio-oncology telehealth consultations in the work of the federal oncology center is demonstrated. Consulting cardiologists are part of a single multidisciplinary team of specialists and must act taking into account the characteristics of cancer and antitumor therapy prescribed by oncologists.
Use of non-steroidal anti-inflammatory drugs during the COVID-19 pandemic. Resolution of the Expert Council of the Russian Society for the Prevention of Noncommunicable Diseases
Authors: Drapkina O. M. , Avdeev S. N. , Gorelov A. V. , Chulanov V. P. , Alekseeva L. I. , Danilov A. B. , Tabeeva G. R. , Pchelintsev M. V.
Published: February 2022

The spread and consequences of the coronavirus disease 2019 (COVID-19) pandemic are currently one of the most pressing public health challenges in the world. Despite the fact that experience accumulates in the treatment and monitoring of COVID-19 patients, certain aspects are still a clinical dilemma. In particular, this regarded the use of nonsteroidal anti-inflammatory drugs (NSAIDs) during the pandemic, both as a symptomatic treatment of infection, and in patients with comorbidities requiring NSAID. A series of studies did not establish evidence of the risk of infection and complications from NSAID therapy in COVID-19. At the same time, the practitioner should take into account the risk of specific NSAID-associated complications, which also remain relevant during the COVID-19 pandemic. This resolution focuses on the evolution of ideas about NSAID use and safety in COVID-19, and also emphasizes the particular relevance of their use for a number of clinical situations.
Additional evidence against widespread use of inpatient antiplatelet therapy in coronavirus infection: data from a randomized controlled trial
Authors: Yavelov I. S.
Published: February 2022

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A taxonomy of bridges at risk of flooding: towards bridge classes and damage models
Authors: Degan Di Dieco Giuseppe , Barbosa Andre R. , Pregnolato Maria
Published: February 2022

Many communities around the world are facing increasing flood-induced damage to bridges due to climate change and rising urbanisation. It is thus crucial to understand how different bridge types suffer from flooding and how this may affect surrounding networks. Despite the large body of literature for seismic and hurricane taxonomies, few classifications exist for bridges at flood risk. In this work, existing global bridge classifications were reviewed in order to derive a bridge–flood taxonomy. The review revealed that existing studies mainly classify bridges according to the superstructure material, whereas subclasses consider superstructure and substructure components. A taxonomy of 20 attributes for riverine roadway bridges susceptible to flood hazards is proposed in this paper. Its applicability for three bridge datasets in the UK was verified. The results showed that the considered datasets have data for 13 attributes, which can be used to derive regional bridge classes. In general, the taxonomy is functional for standardising different bridge datasets and applying/developing damage models for given bridge portfolios of flood-prone countries. Future works could apply the taxonomy to additional bridge datasets within a network for risk assessments; the proposed taxonomy could also be extended to allow integration with functionality and restoration models.
Laboratory Experiments on Performance Evaluation of Geocomposite Drainage Materials
Authors: ÖZDOĞAN DÖLÇEK Ayşe
Published: February 2022

Method of geocomposite drainage systems (GCDs) is relatively new and has been used as an alternative drainage system for geotechnical applications. The advantages of this system are cost- and time efficiency, environmentally sustainable, and at the same time, having comparable or higher drainage capability compared to current practices. However, the geocomposite materials, which is the main products of the GCD systems, need to meet certain criteria that are required for the sufficient drainage systems. These criteria are mainly related to their hydraulic and mechanical parameters that control the systems’ drainage capacity and durability during/after the construction. In this study, laboratory testing and evaluation of five different commercially available geocomposite products are conducted to improve the understanding of their physical, hydraulic and mechanical properties. Physical properties are defined by measuring their thicknesses and apparent opening sizes. Hydraulic parameters; permittivity (volumetric flow rate of water in normal direction) under various hydraulic head was measured using a constant-head equipment. Additional transmissivity and flow rate are defined under various hydraulic gradient and normal compressive stresses using in-plane flow rate testing apparatus. A number of strength testing; compressive strength, grab tensile strength, elongations, trapezoidal and puncture strength are conducted to evaluate the mechanical behavior of the geocomposite products. Results show that the parameters defined for each product are in the same order of magnitude in corresponding testing program, yet some differences are observed when compared with the manufacturer values. The reason of differences and recommendations on the selection of standard testing methods are discussed. Use of a factor of safety (FS) was suggested in the design of geocomposite drainage system when selecting the geocomposite materials.
An Enduring System of Local Deliberative Democracy: The 21st Century Legal and Normative Structure of Massachusetts Town Meeting
Authors: Townsend Rebecca , Reiss Carmin C.
Published: February 2022

This essay examines the legal framework for local deliberative democracy in Massachusetts, within the legislature known as “town meeting.” We review the trajectory of this system of local government allowing direct exercise of citizen power via deliberative governance. We focus on the current framework of state and local laws that were created to support and direct local deliberative systems in Massachusetts with greater attention to functional elements of the system in this legal rhetorical history. We explore the powers of town meeting, including its role within state and federal government, the laws and norms enabling and limiting deliberation, and how and why the legal framework for town meeting has allowed it to endure. Throughout our analysis, we include examples, detailing how philosophical principles of inclusion, self-determination, fairness, and fidelity to the common good underpin town meeting. We note the system's evolution and close with considerations about directions for further changes. The legal framework for town meeting, largely unchanged for close to three centuries, successfully integrates a local community voice into a broader system of deliberative democracy.
Pedagojik Alan Bilgisine Yönelik Bibliyometrik Bir Araştırma: 1987-2020 Yılları Arasında Yapılan Çalışmaların Analizi
Authors: KÖSE Mücahit
Published: February 2022

Araştırmanın amacı pedagojik alan bilgisi ile ilgili yayınların bibliyometrik analizini yapmaktır. Bu amaçtan hareketle 1987-2020 yılları arasında Scopus veritabanında taranan 1760 yayın bibliyometrik açıdan incelenmiş ve son 34 yıldaki eğilim ortaya konmuştur. Veri tabanında “pedagogical content knowledge” anahtar kavramı kullanılarak tarama gerçekleştirilmiş ve yıllara ilişkin yayın sayısı, bu konuda en çok yayın yapan dergiler ve yazarlar, yazarların h indeksleri, sorumlu yazarların ülkeleri ve işbirliği ağları, en çok atıf alan yayınlar, yıllık ortalama alıntı sayısı, yazarların atıf patlama değerleri, kelime bulutu, kelime ağacı haritası ve kavramsal yapı haritası alt başlıklarında incelenmiştir. Elde edilen sonuçlara göre konuya olan ilginin 2002 yılından itibaren arttığı söylenebilir. Bu konudaki makalelerin en fazla yayınlandığı dergi International Journal of Science Education olup, S. Blömeke, G. Kaiser ve M. Rollnick’in bu alanda en fazla makale yazan yazarlar olduğu belirlenmiştir. Pedagojik alan bilgisi en fazla fen ve matematik alanında çalışılmıştır. En fazla oranda Pedagojik alan bilgisinin yapısı, geliştirilmesi ve diğer bilgi türleriyle ilişkileri üzerine araştırmaların gerçekleştirildiği görülmektedir. Brezilya ve Kore’deki araştırmacıların işbirliğine en açık araştırmacılar olduğu belirlenmiştir. Makalelerin keyword ve özet kısmında en çok kullanılan kavramların sırasıyla “teaching”, “pedagogical content knowledge”,” student” ve “education” olduğu tespit edilmiştir. Elde edilen sonuçların bu konuda araştırma yapmak isteyen araştırmacılara ışık tutacağına inanılmaktadır.
MAKİNE ÖĞRENMESİ YÖNTEMLERİYLE EUROLEAGUE BASKETBOL MAÇ SONUÇLARININ TAHMİN EDİLMESİ VE MAÇ SONUÇLARI ÜZERİNDE EN ETKİLİ DEĞİŞKENLERİN BULUNMASI
Authors: ÇENE Erhan
Published: February 2022

Bu çalışmada 2016-2017 ile 2020-2021 yılları arasında oynanan 1358 EuroLeague basketbol maçlarındaki takım istatistikleri göz önüne alınmış ve bu takım istatistiklerinden hangilerinin maçın galibi üzerinde en çok etkiye sahip olduğu belirlenmeye çalışılmıştır. Maçlar, k-ortalama kümeleme analizi sonucunun belirttiği skor farklarına göre yakın, dengeli ve dengeli olmayan olmak üzere üç gruba ayrılmıştır. Hem bu üç grup hem de tüm maçlara k en yakın komşuluk, naive bayes, lojistik regresyon, destek vektör makinaları, karar ağacı, rastgele orman ve yapay sinir ağları algoritmaları uygulanmış ve en etkili algoritmalar lojistik regresyon, destek vektör makineleri ve yapay sinir ağları olarak bulunmuştur. Bu üç algoritma maç sonucunu tüm maçlar için yaklaşık %84 oranında doğru bilmiştir. Yakın maçlarda bu oran %79 a düşmüş, dengeli maçlarda %97 e, dengeli olmayan maçlarda %100 e çıkmıştır. Maç sonucu üzerinde en çok etkili olan değişkenler savunma ribaundu, gerçek şut yüzdesi, top çalma, top kaybı, hücum ribaundu ve denenen serbest atıştır. Burada bulunan sonuçlar takımların maç içi stratejilerini belirlerken en çok odaklanmaları gereken konular üzerinde fikir vermekte ve bu konular üzerine yoğunlaşarak strateji belirlemelerine yardımcı olacağı düşünülmektedir.
Does transversus abdominis function correlate with prone plank and bench bridge holding time in club cricket players?
Authors: Aginsky Kerith Dana , Keen Kirsten , Neophytou Natalia
Published: February 2022

Background: Bridge and plank holding times are used to evaluate core stability. Transversus abdominis (TA) muscle function is assessed using ultrasound and also provides input on an individual’s core stability.
Objectives: A correlation study comparing TA muscle function with bridge and plank holding time in club cricketers.
Methods: Seventeen male, premier league cricketers (age: 22.1 ± 3.3 years) participated in this study. Ultrasound was used to measure bilateral TA, internal oblique (OI) and external oblique (OE) muscle thickness at rest and during abdominal hollowing. Muscle function was measured by means of a Pearson’s correlation as the change in muscle thickness from rest to abdominal hollowing and compared to holding time of the bench bridge and prone plank (seconds).
Results: TA muscle thickness was preferentially recruited bilaterally (p=0.00001) during abdominal hollowing. No significant correlations were found between TA muscle function and holding time for the bench bridge (dominant (D): r = 0.03 [95% CI:-0.46-0.50]; non-dominant (ND): r = -0.02 [95% CI:-0.50-0.47]) or prone plank (D: r = -0.16 [95% CI:-0.60-0.34]; ND: r = -0.13 [95% CI:-0.57-0.38]).
Conclusion: Prone plank and bench bridge holding times are not correlated with TA muscle function during abdominal hollowing. Core stability cannot rely on a single test to evaluate its effectiveness. In particular, the contribution of the local and global muscle system to ‘core stability’ needs to be evaluated independently. Therefore these tests are not sensitive enough to evaluate the contribution of the local muscle system to the global muscle system in a healthy, pain free, sporting population.
That’s not my name: Translation of proper names in Croatian and Russian (re)translations of George Orwell’s Animal Farm: A Fairy Story
Authors: Lukač Dora
Published: February 2022

The procedures for rendering proper names have been studied mostly in works belonging to the fantasy genre and children’s literature. Although George Orwell’s Animal Farm belongs to neither of the two categories, it is affiliated with the subgenre of allegory, which represents quite a challenge to any potential translator. However, the real motivation behind the choice of this book lies in its criticism of the Soviet Union, especially since it was published in 1945, meaning that the political and socio-cultural context influenced its publication and reception to a great extent. This study aims to identify the procedures applied in rendering proper names from Animal Farm in two Croatian (the first translation and retranslation) and four Russian translations (the first translation and three retranslations), and to determine the differences among the translations into the same target language, as well as the differences between Croatian and Russian target texts. Finally, a study of first translations and subsequent retranslations will enable us to detect diachronic changes in the general translation orientations.
Translating neologisms in dystopian literature: Lexical innovation in Aldous Huxley’s Brave New World and its Croatian rendition
Authors: Pelin Dunja
Published: February 2022

This study deals with word formation and translation of neologisms in dystopian literature on the example of Aldous Huxley’s novel Brave New World and its Croatian translation. Its aim is to provide an insight into lexical innovation in dystopias and their translations by relying on Millward’s (2007) theory of dystopian neology. Based on Millward’s theoretical model, the study hypothesizes that coinage is the least frequent, and derivation the most frequent word formation process among source text neologisms. The third hypothesis states that literal translation and lexical creation are the most productive translation procedures. The research consists of extracting source text neologisms and their translations and analyzing the employed word formation processes and translation procedures. The findings show that compounding is the most prolific creation process in source text neologisms, while coinage and conversion are not used at all. The extracted neologisms are mostly rendered through literal translation and borrowing.
Eksplicitacija, ekplicitnost, eksplikacija – terminološki osvrt
Authors: Kegalj Jana , Tominac Coslovich Sandra
Published: February 2022

Eksplicitacija, eksplicitnost ili eksplikacija je pomak u prevođenju kojim prijevodni tekst postaje jezično redundantniji. Eksplicitacija kao jedan od najranije definiranih i najviše istraživanih postupaka u prevođenju, smatra se i univerzalnom strategijom (tzv. prijevodna univerzalija), no nije se značajnije istraživao u prijevodima na hrvatski jezik, pa ni terminologija nije u tom smislu ujednačena. Eksplicitacija je kao univerzalno svojstvo prijevoda primijećena i definirana intuitivno, prije pojave korpusnih alata i deskriptivne struje u znanosti o prevođenju, kvalitativnom analizom izvornika i prijevoda, dok su kasnija korpusna istraživanja dovela do novih spoznaja i dubljeg uvida u ovu pojavu, doprinoseći tako njezinom empirijskom utemeljenju. No, kritičari tih istraživanja upućuju na to kako se različiti fenomeni uvrštavaju pod zajednički pojam eksplicitacije te navode brojne nedostatke njezine definicije. S obzirom na različite nazive koji su se u hrvatskom jeziku upotrebljavali u tom smislu, ovim se radom želi dati terminološki doprinos navedenom pojmu na hrvatskome jeziku tako da se razmotri opseg i sadržaj pojma i s obzirom na to predloži najprikladniji naziv.
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Published: February 2022

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Authors: CBD Gummies Uly
Published: February 2022

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Nested VP1 PCR and Nanopore Sequencing from Stool and ES Samples v1.11 v2
Authors: Shaw Alex , Majumdar Manasi , Troman Catherine , Akello Joyce , Martin Javier , Grassly Nick
Published: February 2022

This protocol is updated from the protocol described in the paper "Rapid and sensitive direct detection and identification of poliovirus from stool and environmental surveillance samples using nanopore sequencing" by Shaw et al in the Journal of Clinical Microbiology (2020), DOI: 10.1128/JCM.00920-20. The protocol aims to amplify the VP1 region of poliovirus through a nested PCR using panEV primers followed by amplification of the VP1 sequence using the Q8/Y7 primer set. We advise the use of barcoded primers where possible as this greatly simplifies the subsequent library preparation process. Additional steps have however been included in the case that the second PCR step is performed either with standard Q8/Y7 primers or using Q8/Y7 with the barcode adaptors (BCA) attached. Primer sequences for the panEV primers, Q8/Y7 primers and modified Q8/Y7 primers are found in Dataset S1 of the publication. Sequencing of the panEV product is also possible through the removal of the VP1 nested PCR steps and the preparation of the panEV product for sequencing. Version updates: v1.1 – Updated to LSK-109 v1.2 – Minor formatting edits v1.3 – Streamlining and minor alterations v1.4 – Written inclusion of negative control in PCR v1.5 – Updated to dreamtaq and Y7R primers v1.6 – Updated MinKNOW instructions & minor edits v1.7 – Changed back to Y7 primers v1.10 – Updated to LSK-110, removed cleaning and quantification prior to pooling, updated taq volume in rtPCR, altered nested VP1 to use neat panEV product. V1.11 – Updated RNA extraction to include Proteinase K, removed DNA CS addition, added pooling of Y7/Q8 primers.
Sistem Tanya Jawab Konsultasi Shalat Berbasis RASA Natural Language Understanding (NLU)
Authors: Sholahuddin Muhammad Rizqi , Atqiya Firas
Published: February 2022

A chatbot is an intelligent system that provides users with direct interaction with machines via written media. This paper describes how to use chatbots to ask questions about prayer procedures. A Muslim sometimes has questions about the procedure for praying when he finds a difference between the procedures performed by other Muslims. In this case, the use of chatbots is to provide an explanation. This chatbot was developed using a deep learning model, especially LSTM, that was integrated with the RASA framework. LSTM (Long Short Term Memory) can efficiently save some of the needed memory while also removing some of the unnecessary memory. The Telegram platform was chosen for the chatbot's implementation. The results showed that the chatbot telegram prayer consultation with DIET Classifier and RASA was able to recognize questions and provide answers in the form of text and images, with 96 percent accuracy.
Kontribusi Interactivate dalam Meningkatkan Minat Pembelajaran Matematika untuk Siswa Sekolah Dasar
Authors: Sylviani Sisilia , Permana Fahmi Candra
Published: February 2022

Di era digital yang semakin pesat saat ini, penggunaan internet merupakan suatu hal yang tidak terelakkan. Dari segala usia, sebagian besar pasti menggunakan internet dalam kehidupan sehari-harinya. Bahkan untuk anak usia sekolah dasar pun kini sebagian besar dari mereka telah menggunakan smartphone baik sebagai alat pendukung kegiatan belajar maupun sebagai sarana hiburan. Salah satu hal yang menjadi ketertarikan anak-anak dalam internet adalah permainan atau game. Bahkan penggunaan game-online saat ini jauh meningkat daripada sebelum-sebelumnya. Hal ini dapat dijadikan sebagai suatu hal yang positif. Dalam paper ini akan dibahas penggunaan game online yang terintegrasi dalam Interactivate dalam meningkatkan minat dan pemahaman Siswa dalam pembelajaran matematika. Dengan penggunaan game ini dapat menjadi salah satu media pembelajaran yang dapat menumbuhkan ketertarikan dan juga pemahaman Siswa khususnya dalam mata pelajaran matematika.