bluuebunny/crossref_metadata_2025 huggingface dataset:
UTILIZAÇÃO DA CLASSIFICAÇÃO INTERNACIONAL DE FUNCIONALIDADE, INCAPACIDADE E SAÚDE EM PEDIATRIA NO BRASIL:
Authors: Damaceno Elielto , Da Silva de Sousa Salomão Danielle , Silva do Nascimento Lais , Evellyn da Penha Ribeiro Brenda , Scardini Menegazzo Nunes Beverly , Cortiana Rodrigues Lima Sabrine
Published: September 2022

Introdução: Em 2001 a Organização Mundial de Saúde aprovou a publicação da Classificação Internacional de Funcionalidade, Incapacidade e saúde (CIF), com o objetivo de promover uma linguagem padronizada para descrição da saúde e dos estados relacionados à saúde através de uma abordagem biopsicossocial. Objetivo: Revisar os estudos que utilizaram a Classificação Internacional de Funcionalidade, Incapacidade e saúde na população pediátrica no Brasil. Métodos: Revisão sistemática elaborada a partir das recomendações PRISMA. As buscas foram feitas em 9 bases de dados diferentes entre agosto e novembro de 2019 utilizando os termos CIF, Brasil e Crianças, em inglês e português, nos anos de 2012 a 2019. Resultados: Foram incluídos 10 estudos observacionais. A maior concentração de publicação foi na área de Fisioterapia (50%), sendo uma grande parte produzida em um contexto multiprofissional na região sudeste do país. Conclusão: Há uma limitação nas áreas acadêmicas estudando esta classificação, com baixa qualidade e quantidade de publicações referindo-se à população pediátrica no Brasil. Os resultados coadunam-se com a literatura, em especial sobre como evidenciam o contraste entre a utilidade desta ferramenta e sua complexidade na aplicabilidade.
Tracheal bronchus and associated pathologies detected by multidetector-row computed tomography in the Vietnamese population
Authors: Lam Khanh , Hoang Luong Van , Anh Lam Viet
Published: September 2022

Tracheal bronchus (TB) is a very rare condition, which is often associated with some other pathologies. This study was designed to characterize the morphology of tracheal bronchus and associated pathologies in Vietnamese individuals using multidetector-row computed tomography (MDCT). From August 2016 to February 2021, 16, 64-, and 128-detector-row computed tomography scanners were used to perform chest scans of 3663 patients, of whom 32 had tracheal bronchus and associated pathologies. The prevalence of tracheal bronchus was 0.9%, of which 0.6% were male and 0.3% were female. We found that one patient had bilateral tracheal bronchus (3.1%) and 31 patients (96.9%) had right-sided tracheal bronchus. Most patients (75.1%) had type II tracheal bronchus, whereas 15.6% and 6.2% had type III and type I tracheal bronchus, respectively. The average distance from the tracheal bronchus to the carina was 6.6 ± 6.4 mm. The average diameter of the tracheal bronchus was 4.4 ± 2.2 mm; the group with 2–4-mm tracheal bronchus accounted for the highest proportion (46.9%). Associated pathologies included congenital heart diseases (i.e., valvular heart disease, tetralogy of Fallot, cyanotic congenital heart disease-APSO, and aortic coarctation) (43.7%), stenosis of the bilateral pulmonary arteries (15.6%), absent left pulmonary artery (6.2%), stenosis of the right pulmonary artery (3.1%), anomalous pulmonary venous connection (3.1%), stenosis of the trachea (3.1%), stenosis of the left main bronchus (3.1%), bronchogenic cyst (3.1%), and bronchial atresia (3.1%), and the remaining 12.5% had no abnormalities. tracheal bronchus is a very rare abnormality among Vietnamese and is often accompanied by other pathologies. MDCT with a high spatial resolution and a good tissue contrast, along with contrast agent and appropriate scanning protocols, is efficient in detecting tracheal bronchus and associated pathologies.
Formation and Stability Analysis of La (III), Er (III) Ho (III) Lomatiol Chelate Complexes
Authors: Amin Mir M.
Published: September 2022

The studies are carried out pH-metrically in which an interaction of trivalent metal cations La (III), Er (III) and Ho (III) under the specific conditions of thermodynamics were done, where the complex formation was achieved within ionic strength consistency and making an infinite dilution where a single mole of trivalent metal, was made to react with 02 moles of lomatiol. The formation constant in stepwise values showed no measurable difference at room temperature, but the complex formation may decline above >400C, as complex stability decreases at high temperature values. The chelate complex formation had been observed as a spontaneous process in solution with the obtained value of ΔG as a negative in all lomatiol metal systems. The observed positive value of change in entropy in all experimental study systems and minus values of free energy also justifies the spontaneity of the reaction. The stepwise formation rate constants (k1> k2> k3) showed a continuous fall in trivalent metal-lomatiol systems assigning the system formation as a normal complex formation.
Studies of mechanical, thermal and electrical properties of guar gum/carbon black composites
Authors: Wadgaonkar Kunal , Maiti Saptarshi , Adivarekar Ravindra , Jagtap Ramanand
Published: September 2022

Polymers have proved to be an indispensable and integral part of our lives. However, prolonged and extensive use of these non-degradable polymers obtained from the non-renewable fossil fuels has led to their accumulation into the environment causing a potential threat to lives. There is a hue and cry about the undesirable consequences of this single-use plastic that needs an immediate answer. The present work contributes to the understanding of conductive polymer composites (CPC) packaging films for electronic goods. The replacement of the polymers used in the packaging of electronic components with bio-based biodegradable polymer films has been attempted. The carbon black was incorporated at varying weight percentages (0.01 to 0.2 wt. %) in the guar gum and the final films were evaluated using FTIR, XRD, DSC and TGA. The electrical properties were evaluated in terms of quality factor, resistance and dissipation factor.
Pairing of applicants’ CJM with university profile in digital environment as a management task
Authors: Arkhipova N. I. , Abaev A. L. , Golova A. G. , Gurieva M. T.
Published: September 2022

The work is devoted to the application of the Customer Journey Map (CJM) for university applicants and managerial tasks of adapting the profile of the university in the digital environment to the trajectories of the consumer. The author’s definition of the “profile of the university in the digital environment” concept is offered, the analysis of statistical data of university websites is made. The combination of classical studies of applicants’ motivation and factors influencing enrollment in a particular university with modern methods of studying consumer behavior in the digital environment allows to increase the effectiveness of the admission campaign. Customer Journey Map as an analysis tool, in conjunction with the data of network traffic allows to optimize all types of communications of the university and provide its management with necessary information when making managerial decisions. The research revealed an insignificant influence of the university social networks and thematic groups on the decision to enroll to a particular university, which what caused a deeper study of visitors’ behavior on the university websites. Internet traffic activity for a number of universities was assessed as direct requests, through search services, social networks, mail servers, as well as through referral links, and advertising traffic. The study showed that search engines and direct queries gave the maximum value for traffic. But the effectiveness of advertising to attract applicants is rather low, which indicates the insignificant role of university advertising and confirms the data of the survey in the construction of the Customer Journey Map.
Electric power (capacity) supply on the wholesale market for industrial consumers operating within the Siberian United Power System: dynamics of price signals changes study
Authors: Dzyuba A. P. , Konopelko D. V.
Published: September 2022

One of the main goals of creating a wholesale electricity market in the Russian Federation was to reduce the prices for circulating electricity. The achievement of this goal was supposed to be due to the development of competitive energy market relations, equal access to electricity supply services to consumers among all participants of the energy market, transparency and structuring of the electricity pricing mechanism. Traditionally, the regions with the lowest prices for supplied electricity in Russia are the territories of the Siberian United Energy System, where the demand for electricity is provided by cheap hydro generation, which ensures the competitiveness of the Siberian economy and high investment potential in the industrial sector. The article presents an empirical analysis of the dynamic changes in the parameters of the total cost of electricity sold in the regions of Russia included various federal districts with a comparison of the cost of electricity in the Siberian Federal District regions with other territories of Russia, with the identification of key trends and features of changes. Analysis of the dynamics of changes in the components of the cost of electricity on various territories for the period January 2021 – March 2022 revealed a significant increase in the cost of electric energy and electric capacity. Their dynamics in some cases exceeds 30 %, and led to a significant increase in prices for electricity sold to all groups of consumers operating in the United Energy System of Siberia regions, and in particular on territories of the Krasnoyarsk Krai and the Republic of Khakassia. The presented article emphasizes the need to study the factors and pricing conditions affecting the change in price parameters for power supplied to consumers operating in the regions of the Siberian United Energy System, with the development of follow-up measures to manage the increase in prices for electricity (capacity) in these regions.
Improved Performance of Positive-ion mode Free Radical-Initiated Peptide Sequencing with para-TEMPO-Bz
Authors: Osho Kemi , Wasik Kim , Geary Laina , Borotto Nicholas
Published: September 2022

Tandem mass spectrometry (MS/MS) is often employed for the sequencing of protein ions and the annotation of protein post-translational modification. Collision-induced dissociation (CID) and electron transfer dissociation (ETD) are the most frequently utilized MS/MS techniques, but both have significant limitations. CID is often funneled into a few kinet-ically labile bonds limiting the effectiveness of sequencing and ETD, is only applicable to multiply charged ions and re-quires specialized instrumentation. Free radical-initiated peptide sequencing (FRIPS) is an alternative fragmentation technique that generates sequence informative ions via collisionally-initiated radical chemistry. Its main advantages over the previously mentioned fragmentation techniques include charge state independence, improved efficiency of sequence ion generation, and applicability to most MS instrumentation. Collision activation (CA) homolytically cleaves the radical precursor, initiates radical formation, extensive hydrogen atom transfer, and peptide backbone dissociation. Although the FRIPS technique shows great promise when applied to cations, radical initiation competes directly with typical CID path-ways. When multiply charged ions of conjugated ACTH 1-14, b-amyloid 10-20, substance p, and melittin are collisionally activated, a series of high abundance mass losses are observed which syphon ion abundance from radically generated sequence ions. This loss of ion abundance reduces the sequence coverage generated by FRIPS fragmentation. In this work, we hypothesized that these mass losses were instigated by the ortho-orientation of the radical precursor undergoing fac-ile conversion into five- or six-membered intermediates and that the para-precursor would not undergo this chemistry. To test this assertion, we synthesized para-TEMPO-Bz, conjugated it to these peptides, and collisionally activated each. And indeed, we see the complete elimination of these undesired collisional processes and the significant increase in radi-cal precursor ion abundance. Moreover, we see a significant increase in the sequence coverage generated when the p-TEMPO-Bz is utilized. From these results, p-TEMPO-Bz significantly improves the performance of positive-ion mode FRIPS and may be a suitable alternative to the currently utilized ortho-TEMPO-Bz-based FRIPS.
Characterizing the Top-down Sequencing of Protein Ions Prior to Mobility Separation in a timsTOF
Authors: Graham Katherine , Lawlor Charlie , Borotto Nicholas
Published: September 2022

Mass spectrometry (MS)-based proteomics workflows of intact protein ions have increasingly been utilized to study bio-logical systems. These workflows, however, frequently result in convoluted and difficult to analyze mass spectra. Ion mobility spectrometry (IMS) is a promising method to overcome these limitations by separating ions by their mass- and size-to-charge ratios. In this work, we further characterize a newly developed method to collisionally dissociate intact protein ions in a trapped ion mobility spectrometry (TIMS) device. Dissociation occurs prior to ion mobility separation and thus, all product ions are distributed throughout the mobility dimension, enabling facile assignment of near isobaric product ions. We demonstrate that collisional activation within a TIMS device is capable of dissociating protein ions up to 66 kDa. We also demonstrate that the filling of the TIMS device significantly influence the efficiency of fragmentation. Lastly, we compare CIDtims to the other modes of collisional activation available on the Bruker timsTOF and demon-strate that the mobility resolution in CIDtims enables the annotation of overlapping fragment ions and improves sequence coverage.
The use of animals in hooliganism and other crimes committed with hooligan motives
Authors:   Research Institute of the Russian Federal Penitentiary Service, Pleshakov A.M.
Published: September 2022

The features of criminal-legal estimation of use of representatives of fauna at hooliganism and other crimes which are made with hooliganism motives are considered. The author points out inconsistency of the settled judicial-investigative practice of recognizing dogs as an object used as a weapon during commitment of a crime. The subjective signs of the use of animals during the commitment of the researched acts are analyzed. Practical examples of bringing to responsibility of persons who use animals during the commission of a crime under Art. 213 of the Criminal Code and other acts of hooliganism are demonstrated.
Some aspects of comparative legal analysis of the legal regime of specially protected natural areas in the Republic of Korea and the Russian federation (using lake Baikal as an example)
Authors:   Irkutsk State University, Shornikov D.V.
Published: September 2022

As part of the implementation of the project for building the concept of international legal protection of Lake Baikal, supported by the Russian Foundation for Basic Research, the main components of the modern legal regime of specially protected natural areas in the Republic of Korea are considered. Based on the comparative legal method of research, the genesis of the formation of a system of specially protected natural areas in the Republic of Korea is analyzed, the main features of the modern components of this system are considered, and a number of statistical data in the study area are given. A detailed analysis of the provisions of the main normative act regulating public relations in the field of creation, management and development of protected areas - the Act on Natural Parks of the Republic of Korea is given. A general idea of the composition of special legislation in the area under study is given. A number of conclusions have been drawn that allow transposing the accumulated experience in the formation, management and development of the protected area system in the Republic of Korea to the relevant law-making, managerial and law-enforcement field of activity in the Russian Federation, primarily in terms of preserving the unique ecosystem of the UNESCO world natural heritage site – Lake Baikal.
Ancient Ethnic Origins of Baikal Images and Their Modern Applied Significance in Politics and Business
Authors:   Irkutsk State University, Karnyshev A. D. , Ivanova E. A. ,   Irkutsk State University, Karnysheva O. A. ,   Irkutsk State University
Published: September 2022

The authors show that the image of Baikal has evolved from the concept of the northern and inner sea (tengiz) with its similarity to many ice ponds to the source of wealth and the center of healing, sacred and spiritual resources. The article considers to what extent the version about the stay of Chingiz Khan on Baikal and his island Olkhon, as well as the mention from Mongolian sources about the burial of this warrior at the “big water Baigal”. In political terms, the article rejects the thesis of radical Chinese figures that Lake Baikal was part of China, on the contrary, it shows that these places could not have been native to the Chinese Xiongnu captives: “ten years lived with barbarians in cruel captivity”.
Formation of Theoretical and Methodological Foundations of Cyclic Concepts in the Political Sphere: On the Example of the Works of Scientists of the Age of Enlightenment
Authors:   Scientific and Practical Center for the Problems of Strengthening Law and Order of the General Prosecutor's Office of the Republic of Belarus, Khudyakov A. V.
Published: September 2022

The complication of relations in the society of the Enlightenment required the development of a scientifically based foresight of political dynamics. This led to the interest of scientists in cyclic concepts. Within the framework of the comparative-historical and systematic approach, the author considers the formation of their theoretical and methodological foundations. The main attention is paid to the content of the concepts. It is considered in the context of the worldview that dominated the Enlightenment. Each concept is an ideal scheme where scientists describe a complex reality in a simplified way. This made the theories open to criticism and further scientific research. The author comes to the conclusion that since the Enlightenment there have been four trends in the process of forming the theoretical and methodological foundations. First, the concept of linear progress is firmly established in the social sciences. In the future, it served as the basis for political research. Secondly, scientists finally departed from the religious worldview. In their writings, they laid the foundations for a logical and rational approach to the study of the development of society. Thirdly, the bourgeois revolutions generated an interest in the study of social conflicts. To analyze changes in society, scientists used cyclical and linear approaches. Fourthly, interest in the topic of the “golden age” has been preserved in society. During the Age of Enlightenment, this topic was further developed. Scientists have made attempts to realize abstract models of an ideal society.
Towards the Sovereignization of Social Science: Notes in the Margins of an Editorial
Authors:   Irkutsk State University, Bukhantsov V. V. , Komarova M. V. ,   Irkutsk State University
Published: September 2022

In the traditions of Russian socio-philosophical reasoning (“discourse”) methodological and theoretical problems of social science are posed and approaches to their solution are proposed, taking into account the peculiarities of cognition of the second Nature, in the process of which feelings, reason and intuition participate. The principles and main aspects of the methodology are postulated. The main objects of research are highlighted: local civilization and the state. The definition of the “state” as a supra-historical creator of history is given, its two main formations of modern times with their features are indicated: the empire and the national state. The author's understanding of politics and public institutions is also given. The end–to-end idea of the work, at the same time its premise, and the inevitable consequence is the need for a sovereign Russian social science, sprouting from the domestic sociophilosophical heritage.
Vectors of Explanation of Religious Architecture in the Optics of the Psychology of Religion
Authors:   Lomonosov Moscow State University, Begchin D. A.
Published: September 2022

In this research paper was implemented a search for general philosophical and scientific principles and possibilities of the study of religious architecture in the optics of the psychology of religion. For this purpose were involved the achievements of M.R. Savchenko in the field of architectural ontology and functional methodology. It was shown that the study of architecture from the position of psychology of religion should pursue psychological explanation of the need for religious architecture for the preservation (survival, spread, development) of ritual and religion. This type of explanation is possible on the basis of a functional methodology that allows the study of architectural processes that cannot be reduced to the cultural processes of understanding, interpretation of communication. It was shown that the study of architecture from the point of view of the psychology of religion is possible in the light of the theories of contemporary evolutionary psychology, Jungian psychoanalysis, as well as the psychology of visual perception. If we use the theories from these strands of psychology, we can argue that certain processes and properties of religious architecture do not belong to cultural processes or properties of cultural institutions, but nevertheless they affect culture, contribute to the preservation of ritual and provides the psychotherapeutic, compensatory and adaptive functions of religion.
A Current Past: an exploration into the resurgence of waterways in modern urbanscapes of Aotearoa New Zealand
Authors:   , Whaley Isabel
Published: September 2022

With over half the global population living in urban centres, we are called to question how these environments are structured and how they can function both socially and sustainably. As society evolves, Aotearoa New Zealand's urban centres need to reinvent themselves as social and cultural centres rather than retail ones. Urbanscapes of mid-size cities remain trapped by the gridded structure imposed on them by nineteenth-century surveyors. Streams that sustained their diverse landscapes now lie buried under our urban streets, in concrete channels or under waste and refuse at the exterior of the built form. Concealed with these waters are the stories of a land and people past, and hopes for a sustainable and integrated future. Urban water offers an opportunity to re-spatialise our vehicle-dominated cities and restore identity through a connection to the memory of the land. These forgotten arteries offer to reinvigorate a CBD in danger of becoming socially irrelevant. Changing attitudes, such as Te Mana o te Wai governance and recognition of freshwater cultural health indicators, are clear signs of a society eager to rethink our relationships with urban water. Furthermore, with over 95% of rivers in pastoral, urban and non-native forested areas contaminated, the time is now.

Similarly to mid-size cities around New Zealand, New Plymouth has unique natural landscapes and histories; however its urban centre, with an outdated retail focus, struggles to remain relevant. The city is physically and culturally defined by its coast and its mountain; despite this, the city centre remains disconnected from these natural features. The water flowing from its mountain to its sea offers a perfect research opportunity of a catchment-scale approach to re-integrating urban waterways into a cityscape, reinstituting water as the literal and cultural link from mountain to city to sea. Water offers to resolve New Plymouth District Council's concerns that the city will become a ghost town due to vehicular dominance and changing retail trends.

This thesis seeks to reimagine the identity of Aotearoa New Zealand urbanscapes as vibrant social and cultural centres. Connecting forgotten waterways and revealing histories and identities of a land and people past, it explores what urban interaction with our water may look like in a uniquely New Zealand context. Focusing on streams in the CBD and a wider ki uta ki tai mountains to sea approach, site-informed exploration suggests how freshwater can spatially define an urbanscape, engage community with a site's history in an experiential rather than signposted way to become a living social structure.
The Infill Neighbourhood
Authors:   , Ferrick Ambrose
Published: September 2022

Wellington is set to expand tremendously in the next thirty years with an expected rise in population by up to 80,000 people. This creates the ongoing problem of how to house these people and where. The most common answer to this problem is to build up or to build large apartment complexes. However, in a city known for its eclectic personality and urban landscape this is not the most desirable option. Wellingtonians want expansion to happen in the current urban areas and for it to be ‘compact, vibrant, inclusive and greener’. (Wellington City Council, 2020) Infill housing, defined by the Wellington city council, is the process of building new dwellings within an existing suburb of older houses. In other words, infill housing is the addition of new housing interventions, whichever form they take, into established neighbourhoods. Infill housing can take on many forms, and this has led to apprehension in many New Zealand neighbourhoods. There are many implications to infill housing which have a large impact on the social, cultural, and contextual aspects on a neighbourhood, otherwise referred as the character or sense of place.

 Wellington is looking for a new solution to its inevitable housing shortage and perhaps new building interventions to solve this problem. The investigation and application of this model in a New Zealand context is set out to create areas of higher density different to typical approaches and which improve urban amenity while simultaneously improving housing quality.

 An investigation is to be carried out to determine how defining and adapting what infill housing is can have a positive impact within the New Zealand context, in particular Wellington. Through intensive research and adaptation to a Wellington site a successful intervention would produce new, interesting infill housing that would integrate well and could be used and adapted to other cities in New Zealand and successfully integrate itself within the character of established neighbourhoods.
Family Support Situation and Educational Strategies for Primary School Children with Intellectual Disabilities Learning in Regular Class
Authors: Lu Zuqin
Published: September 2022

This paper aims to verify the family support situation for primary school children with intellectual disabilities learning in regular class and to explore various educational strategies to promote their development. A self-made questionnaire was used in this survey, and the parents of 380 intellectual disabled students were the subjects of this survey. It turns out that the overall family support for intellectual disabled children learning in regular class in China is good, but it is affected by the degree of obstacles. Factors such as grade, gender, and parental education had no significant effect on family support. It is the shared responsibility of the government, schools, and parents to promote the level of family support. Governments at all levels must implement family support projects, schools must carry out family education guidance to impart scientific parenting knowledge, and parents must take note of their own responsibilities, so as to promote the physical and mental development of children with intellectual disabilities.
The Mobility of International Students from a Chinese Perspective
Authors: Zhu Jiangye , Gao Yuan
Published: September 2022

This paper focuses on examining the progression of the international education market, the number of international students in various countries, and China’s policy to support and liaise with the international universities. From the perspective of “talent demand,” this research will provide valuable insight into China’s acquisition of talents and higher education internationalization development.
CT Differentiation of Diffuse Malignant Peritoneal Mesothelioma, Tuberculous Peritonitis, and Peritoneal Carcinomatosis
Authors: Song Hui , Zheng Guo-qi , Chen Yue-feng , Yang Dong-liang , Zhang Li , Xu Yan-feng
Published: September 2022

Objective: To investigate the significance of computed tomography findings in diffuse malignant peritoneal mesothelioma (DMPeM), tuberculous peritonitis (TBP), and peritoneal carcinomatosis (PC) to differentiate the three diseases. Methods: The clinical manifestation and computed tomography scans of 147 patients with diffuse malignant peritoneal mesothelioma (n = 60), tuberculous peritonitis (n = 32), and peritoneal carcinomatosis (n = 55) were retrospectively reviewed, while taking into account of ascites, pleural plaques, viscera infiltration; abnormalities in the peritoneum; involvement of the mesentery and omentum; as well as the presence and location of enlarged lymph nodes. Results: There was no significant difference among all three groups in terms of clinical manifestation, peritoneum, omentum, and mesentery involvement, ascites, as well as the presence and location of enlarged lymph nodes. The study found that 95% of DMPeM patients had been exposed to asbestos in the past. The patients showed significant differences in the following aspects: (1) irregular peritoneum thickening, caked omentum thickening, pleural plaques, visceral infiltration, and asbestos exposure were more common in peritoneal mesothelioma patients; (2) nodular peritoneum thickening and visceral metastasis were more common in patients with peritoneal carcinomatosis; (3) smooth peritoneal thickening, pleural effusion, and extraperitoneal tuberculosis were more common in patients with tuberculous peritonitis. Conclusion: A combination of computed tomography findings could improve our ability in differentiating the three diseases.
Research Progress of Prostate Stem Cell Antigen in Bladder Cancer Treatment
Authors: Li Jinmei , Cheng Runfen , Zhou Bingjuan , Zhang Zhiqiang , Zhai Qiongli , Zhang Jinku
Published: September 2022

In order to study the application effect of prostate stem cell antigen in the treatment of bladder cancer, several literatures have been reviewed in this paper, including the predisposition factors of bladder cancer, clinical treatment methods, progress of prostate stem cell antigen, and nanomaterial probe. This paper presents a feasible method of using luminescent nanomaterials (anti-UCNPs) as biological probes.
Mechanism of Ginsenoside Rh1 in Regulating Breast Cancer Cell Extravasation Based on CCL20-CCR6
Authors: Zhao Wenming , Zhou Binjuan , Sun Jirui , Qiao Haizhi , Ma Shuangqui , Wang Xu , Zhang Jinku , Li Jinmei
Published: September 2022

Objective: To explore the regulatory mechanism of ginsenoside Rh1 on breast cancer cell extravasation based on CCL20-CCR6. Methods: In 2021, a total of 34 patients with breast cancer were treated in Baoding First Central Hospital. During hospitalization, pathological examinations were performed, and all the patients were diagnosed with invasive ductal carcinoma. Out of the 34 cases, 16 cases were found to have CCR6 expression in breast cancer tissues, in which they were recorded as the CCR6 expression group, whereas 18 cases did not have CCR6 expression; these cases were recorded as the CCR6 non-expression group. During the same period, 21 normal patients were selected as the control group. The peripheral blood CCL20 level and the expression of CCR6 on the surface of CD3+ T lymphocytes were analyzed. The extracts of cancer cells were collected, purified, and cultured, and the effect of ginsenoside Rh1 on the invasion and metastasis of breast cancer cells was analyzed. Results: The peripheral blood CCL20 level in the CCR6 expression group was significantly higher than that in the CCR6 non-expression group and the control group, in which p < 0.05, indicating that the difference was statistically significant; at 12, 24, and 48 hours, the cell survival rate of each dose group was significantly higher than that of the blank control group and the dimethyl sulfoxide (DMSO) group (p < 0.05). At 48 hours, comparing the low-dose group with the high-dose group, the cell survival rate significantly decreased (p < 0.05). Compared with the blank control group and DMSO group, the invasion ability of breast cancer cells could be reduced in both, high- and medium-dose groups, where p < 0.05, indicating that the difference was statistically significant. Conclusion: CCL20 may play a role in the pathogenesis of certain breast cancers, and ginsenoside Rh1 can effectively regulate the invasion and migration of breast cancer cells.
Mercado de trueque y seguridad alimentaria en los distritos de Acora e Ilave de Puno-Perú: periodo 2015-2017
Authors: Huarachi-Coila Luis
Published: September 2022

Algunas familias ubicadas en los sectores pobres no tienen recursos monetarios suficientes para la sobrevivencia, por ello, desde épocas ancestrales se practicó y lo siguen practicando el trueque como una forma de dar y recibir algún bien o servicio que carecen; cambiar un objeto por otros por necesidad sin la intervención dinero. Por ello, este estudió buscó evidenciar de qué manera el trueque se practica con mayor frecuencia como medio de subsistencia a la pobreza para cubrir la demanda insatisfecha, básicamente de alimentos. El procedimiento metodológico consistió en la aplicación de una encuesta a las familias que realizan el trueque en los distritos de Acora e Ilave, entre los meses de diciembre del 2015 a diciembre del 2017 en épocas de campaña agrícola; la información recolectada fue procesado con SPSS. Los resultados evidencian que el trueque tiene plena vigencia de intercambio de objetos disponibles con otros bienes requeridos para garantizar la seguridad alimentaria en la que no interviene el dinero. Proceso que se le denomina también permuta, dar lo suyo (propiedad) para recibir otros bienes equivalentes al bien dado. En la antigüedad se usaba más el intercambio de materia prima por artesanía o productos para la alimentación. La ventaja radicaba en que se mantenía stock de productos para propender a otros canales de comercialización. Se concluye, que a pesar de la persistencia del trueque con resultados favorables no siempre fue posible encontrar los otros bienes buscados, al igual que la equivalencia de los bienes no siempre calculan la valía real del bien en cuestión del trueque, de que se corren riesgo de perder por valor.
Kohezyonlu zeminlerde net limit basınç ve deformasyon modülünün makine öğrenimi temelli modeller kullanılarak tahmin edilmesi
Authors: GÜLTEKİN Nurgül , DOĞAN Ayhan
Published: September 2022

Makine öğrenimi temelli yöntemler son dönemlerde özellikle mühendislik uygulamalarında geniş bir alan bulmuştur. Çalışma kapsamında kohezyonlu birimlerde gerçekleştirilmiş arazi ve laboratuvar deneylerinden elde edilen veriler kullanılarak net limit basınç (PLN) ve deformasyon modülü (E) değerleri tahmin edilmeye çalışılmıştır. Bu amaçla; Regresyon Ağaçları (RA), Destek Vektör Makineleri (DVM), Gauss Süreç Regresyonu (GSR) olmak üzere üç farklı makine öğrenimi yöntemi kullanılmıştır. Düzeltilmiş SPT (SPT-N(60)), likit limit (%LL), plastisite indeksi (%PI) ve birim hacim ağırlık (BHA) verileri modellerin girdi parametrelerini oluşturmaktadır. Her bir model için üç makine öğrenimi yöntemi de uygulanmıştır. Buna göre; çalışma kapsamında DVM ve GSR yöntemleri RA yöntemine göre daha yüksek tahmin performansı göstermiştir. PLN’nin ve E’nin tahmin edilmesine yönelik oluşturulan modeller karşılaştırıldığında ise; PLN’nin tahmin performansı daha yüksek çıkmıştır. Sonuç olarak; üç farklı makine öğrenimi yönteminin de PLN’nin ve E’nin tahmininde kullanılabileceği, özellikle arazi çalışmalarının yüksek maliyetli olduğu, örnekleme çalışmalarının güçlüğü gibi durumlarda temsil kabiliyetinin yüksek olduğu sonucuna varılmıştır.
Decolonialidade e Conteúdos Cordiais: Caminhos Possíveis Para Estabelecer Relações Entre Ensino de Ciências e Educação em Direitos Humanos
Authors: Da Silva Alves Claudia Thamires , Ribeiro do Amaral Edenia Maria , Simões Neto José Euzebio
Published: September 2022

Nossas sociedades são constituídas por múltiplas existências que se relacionam dentro de sistemas que negam humanidades e intelectualidades a indivíduos e grupos fora dos padrões estabelecidos. Questões sobre exclusão social perpassam o Ensino de Ciências, ainda que propostas e estudos sejam feitos de forma acrítica e com uma pseudoneutralidade que invisibiliza a diversidade de pessoas e de discursos associados a conceitos científicos. Buscando caminhos, analisamos a proposta de formação de professoras(es) como agentes socioculturais e políticos, a decolonialidade e os conteúdos cordiais como formas de relacionar o Ensino de Ciências à Educação em Direitos Humanos e abrir caminhos para abordagens inclusivas. Planejamos a aplicação e análise de oficinas pedagógicas, que discutiram concepções sobre direitos humanos e conteúdos químicos em situações que envolvem esses direitos. No primeiro momento, estudantes apresentaram soluções para situações hipotéticas de violações de direitos humanos na sala de aula e no segundo planejaram propostas ancoradas nas pedagogias decoloniais e nos conteúdos cordiais. Os resultados apontam inicialmente para abordagens superficiais, porém, no segundo momento, os licenciandos trouxeram os conteúdos químicos associados à decolonialidade e aos conteúdos cordiais. Destacamos a importância das relações propostas para os processos educacionais e para a construção de sociedades que reconheçam e valorizam a diversidade e buscam romper com a colonialidade.
The Effect of Remote Learning, Family Condition, and Mental Resilience on Depression Symptoms of Early Childhood
Authors: Karta I Wayan , Rasmini Ni Wayan , Widiana I Wayan , Ujianti Putu Rahayu
Published: September 2022

The Covid-19 pandemic that attacked Indonesia and other countries of the world has changed human’ way of life. The Covid-19 pandemic greatly influences the field of education, where all learning activities turn to online mode, which results in students’ depression symptoms due to their unpreparedness. This study aims to analyze the impact of remote learning, family conditions, and mental resilience on depression symptoms in early childhood. This study used ex-post facto research (measurement after the event) because the research data for both independent variables and dependent variables occurred before this study was held. The study population was 80 children. The data collection method used was a questionnaire developed from the indicators of each variable. The analysis method used multiple regression. The data analysis used correlation and regression techniques, with regression analysis of three predictors and one criterion. The research findings showed that depression symptoms of early childhood are jointly influenced by remote learning, family condition, and mental resilience. However, two variables that do not affect the depression symptoms of early childhood are remote learning and mental resilience. It can be recommended that parents and parties involved in early childhood education give more attention to children. Doi: 10.28991/ESJ-2022-06-06-013 Full Text: PDF
Self-Regulated Learning dan Self-Control Pada Mahasiswa Pendatang
Authors: Rinawati Rinawati , Adyani Liza
Published: September 2022

Educational isn't always between teacher and student, even each individual can arrange their learning or what is called learning with their arrangements. This of course requires good self-control from every learner. This study aims to determine the relationship between independent learning and self-control in students through a cross-sectional approach. The population and sample of this study were West Sumatra 2016-2018 students studying at Malikussaleh University using quota sampling. Primary data collection is done by utilizing self-regulated learning scales and self-control scales. Hypothesis test results indicate the value of the correlation coefficient (r = 0.553) at a significance level of 0,000 (p <0.001). The state of this statistical value can be interpreted that the working hypothesis has a significant relationship between the two variables studied.
Iklim Organisasi dan Komitmen Kerja Karyawan Puskesmas
Authors: Alfa Tri Yaumil , Iramadhani Dwi , Djafar Azwar
Published: September 2022

The working atmosphere in the company is very important in determining employee performance and work commitment. This study aims to determine the relationship of organizational climate with work commitments for employees in Puskesmas Kutamakmur, Aceh Utara. The hypothesis being tested is a positive relationship between organizational climate and work commitments for employees who work in Puskesmas Kutamakmur. The sampling technique used in this study was sampling saturation with data collection methods through the organizational climate scale and Likert work commitment scale model for 120 employees. The reliability test produces an organizational climate of 0.880 and a work commitment of 0.911. Hypothesis test results show a positive relationship with organizational climate and work commitment based on the value of the correlation coefficient r = 0.455 (p = 0,000).
UPAYA PELESTARIAN MANGROVE MELALAUI PERBAIKAN TEKNIK PEMBIBITAN DI DESA JEROWARU, KECAMATAN JEROWARU, KABUPATEN LOMBOK TIMUR
Authors: Rahman Ibadur , Buhari Nurliah , Damayanti Ayu Adhita , Jefri Edwin , Lestariningsih Wiwid Andriyani
Published: September 2022

Ekosistem mangrove dewasa ini kian mendapatkan tekanan terutama disebabkan kegiatan alih fungsi lahan mangrove menjadi area pertambakan, kawasan wisata dan industri. Padahal ekosistem mangrove memiliki peranan yang sangat vital bagi kehidupan. Upaya telah dilakukan untuk memperlambat laju degradasi ekosistem mangrove, diataranya dengan melakukan kegiatan penanaman kembali (reboisasi). Kegiatan penanaman mangrove seringkali terkendala kurang sehatnya bibit yang digunakan, atau kekurangsesuaian antara bibit dengan lingkungan penanaman. Hal tersebut mengakibatkan bibit mangrove yang ditanam tidak mampu tumbuh dengan baik bahkan mengalami kematian. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk memberikan edukasi dan pendampingan kepada maysarakat di Dusun Poton Bako, Desa Jerowaru, Kecamatan Jerowaru, Kabupaten Lombok Timur mengenai teknik pembibitan mangrove khususnya jenis R. mucronata dan S. alba dengan baik dan benar. Metode yang digunakan adalah menggunakan media booklet, dan pendampingan praktek secara langsung. Dimana masyarakat mendengarkan dan mempraktikan apa yang sudah disampaikan mengenai tata cara pembibitan. Hasil kegiatan ini mendapatkan antusiasme yang tinggi dari masyarakat dan dirasakan kebermanfaatannya oleh masyarakat. Kegiatan pendampingan ini memerlukan tindak lanjut berupa pengontrolan dan pendampingan yang berkesinambungan, sehingga program pembibitan yang kedepannya dilakukan secara mandiri oleh masyarakat dapat berlanjut dan berjalan optimal.  Ke depan, yang diharapkan seperti kemandirian masyarakat untuk melakukan pembibitan mangrove dapat berjalan dengan baik. Dengan demikian apa yang sudah didapatkan oleh masyarakat bisa ditularkan kepada orang lain, sehingga pelestarian mangrove tetap terus terjaga.
Strategi Pengelolaan Sampah dalam Mendukung Program Zero Waste di Desa Pulau Maringkik
Authors: Warman Krisna Aditya , Budiman Budiman , Safira Ersa , Arta I Gede Krisna Dharma , Rosalinda Siska , Diana Putri , Lajuardi Didik Rijal , Fatinah Amira , Hidayat Dandy , Marlina Dea , Malazy Muhammad Akmal , Fathony Muhammad Dira , Wahidatussolihah Rosanti , Harahap Herpan Syafii
Published: September 2022

Maringkik Village is a fishing village located in East Lombok. This village has promising tourism potential due to the condition of the island which is surrounded by beaches with beautiful landscape. The natural beauty of Maringkik Village is starting to be covered by a serious waste problem, one of the waste problems is the unavailability of proper garbage dump, so people throw garbage into the sea or on the coast which results in environmental pollution. Therefore, an effort is needed to overcome this problem. There are several efforts that are expected to decrease the waste problem in Maringkik Village, among others, implementing a waste audit, socializing waste management and waste banks, establishing a waste bank and processing plastic waste into Eco brick that can be created into useful goods.
Penulisan Kajian Literatur: Solusi Riset Di Masa Pandemi
Authors: Aini Siti Rahmatul , Pratama Iman Surya , Hajrin Wahida , Hanifa Nisa Isnaeni , Febrianto Surya , Hidayat Lalu Husnul
Published: September 2022

COVID-19 pandemic condition presents obstacles for lecturers and students of the Pharmacy Study Program in all aspects of life, including the educational aspect. One of the obstacles faced is the limitations of lecturers and students of Pharmacy in conducting field and laboratory research, so that it can have an impact on delays in the implementation of the tridharma. Literature review can be an option in overcoming these obstacles. This community service aims to improve targeting capabilities and design a literature review study as an alternative research solution during a pandemic. The method used in this activity is in the form of delivering material and guided discussions through webinars with the zoom meeting platform and YouTube Livestreaming on the Pharmacy account of the University of Mataram. The webinar is divided into 2 sessions, namely a material presentation session and a clinical session for writing scientific articles with experts. A total of 77 participants attended the activity consisting of lecturers from health groups and pharmacy students. The enthusiasm of the participants was quite high as evidenced by a number of questions submitted in the discussion session. Participants' responses to the activities ranged from 4.2 to 4.7 which indicated that the event was going well with an assessment using a Likert scale from 1 to 5. The components of the assessment included time suitability, material suitability, participants' understanding of the material, moderator behavior, benefits of the event for participants and participant's opinion on the event. The ability of community service participants increases in designing literature studies through the output of articles that will be submitted in reputable journals.
Pemanfaatan Lahan Non-Produktif Sebagai Lahan Budidaya Tanaman Pangan Rumah Tangga di Kelurahan Prapen, Lombok Tengah
Authors: Rizky Muhammad Robby , Wahyuni Nanda Hikkal , Saptaningtyas Rini Srikus
Published: September 2022

The Sustainable Food House Program (RPL) implemented by the Tematic KKN Group at the University of Mataram is one of the concepts of using non-productive home gardens both in rural and urban areas to support national food security by empowering local food potential. Especially those around areas that have narrow land which makes it difficult for residents who live in the area to meet their basic needs, such vegetables and fruits which are included in staple consumption for residents, one of the efforts to overcome this is by sharing knowledge. Along with experiences with residents such as planting methods and other new methods or breakthroughs. The purpose of implementing this RPL program is to be able to utilize and optimize non-productive land to become productive, improve the family economy, meet family food and nutritional needs, and overcome waste problems.