bluuebunny/crossref_metadata_2025 huggingface dataset:
Tracked Robot Control with Hand Gesture Based on MediaPipe
Authors: Wameed Marthed , M. ALKAMACHI Ahmed , Erçelebi Ergun
Published: September 2023

Hand gestures are currently considered one of the most accurate ways to communicate in many applications, such as sign language, controlling robots, the virtual world, smart homes, and the field of video games. Several techniques are used to detect and classify hand gestures, for instance using gloves that contain several sensors or depending on computer vision. In this work, computer vision is utilized instead of using gloves to control the robot's movement. That is because gloves need complicated electrical connections that limit user mobility, sensors may be costly to replace, and gloves can spread skin illnesses between users. Based on computer vision, the MediaPipe (MP) method is used. This method is a modern method that is discovered by Google. This method is described by detecting and classifying hand gestures by identifying 21 three-dimensional points on the hand, and by comparing the dimensions of those points. This is how the hand gestures are classified. After detecting and classifying the hand gestures, the system controls the tracked robot through hand gestures in real time, as each hand gesture has a specific movement that the tracked robot performs. In this work, some important paragraphs concluded that the MP method is more accurate and faster in response than the Deep Learning (DL) method, specifically the Convolution Neural Network (CNN). The experimental results shows the accuracy of this method in real time through the effect of environmental elements decreases in some cases when environmental factors change. Environmental elements are such light intensity, distance, and tilt angle (between the hand gesture and camera).The reason for this is that in some cases, the fingers are closed together, and some fingers are not fully closed or opened and the accuracy of the camera used is not good with the changing environmental factors. This leads to the inability of the algorithm used to classify hand gestures correctly (the classification accuracy decrease), and thus response time of the tracked robot's movement increases. That does not present possibility for the system to determine whether the finger is closed or opened.
Creating a LabVIEW Sub VI for the INA219 sensor for detecting extremely low-level electrical quantities
Authors: B. Khudhair Abdulrahman , Hussein Furat I. , Obeidi Muhannad Ahmed
Published: September 2023

يتطلب نظام الحماية الكاثودية للتيار القسري (ICCP) قياسات كميات منخفضة للغاية من الخصائص الكهربائية. استخدم العمل التجريبي الحالي وحدة مستشعر Adafruit INA219 للحصول على  قيم الجهد والتيار وقدرة  الحمل الافتراضي الذي يستهلك طاقة منخفضة جدًا تحاكي نظام ICCP. تكمن المشكلة الرئيسية في تكييف مستشعر INA219 مع بيئة LabVIEW بسبب عدم وجود مكتبة المستشعر هذا. تم تخصيص هذا العمل لتكييف وحدة استشعار Adafruit INA219 في بيئة LabVIEW من خلال إنشاء Sub VI وتطويره واختباره بنجاح ليكون جاهزًا للعمل في نظام ICCP. تمت مراقبة إخراج المستشعر باستخدام متحكم Arduino Uno ومجموعة أدوات البرامج الثابتة LabVIEW Linx. تم تطبيق تقنية تعديل عرض النبض (Pulse Width Modulation (PWM) ، والتي تتراوح من 0٪ إلى 100٪ ، بواسطة Arduino لتزويد متحكم الجهد l298N من أجل تنظيم إدخال الجهد للحمل. تم استخدام مرشح متوسط متحرك لقياس متوسط جهد التموج ، وتم استخدام مرشح متوسط لتثبيت القراءات. تقوم دائرة المرشح  بتنعيم جهد PWM قبل تزويده الى الحمل. أظهرت النتائج من بيئة MATLAB-Simulink أن تردد القطع عند 2.33 هرتز ، و جهد التموج من اعلى قيمة الى اقل قيمة  كان 41.1 مللي فولت وزمن استقرار قدره 0.157 ثانية. أظهرت النتائج التي تمت معايرتها لمستشعر وحدة INA219 عدم دقة الجهد المطلق بحوالي 2.3٪ على النطاق الكامل. بالإضافة إلى ذلك ، كانت قيمة الخطأ المطلق في التيار بنسبة 2.2٪ عند 25 مللي أمبير ويزداد  تدريجيا بازدياد قيمة التيار  حيث قيمة الخطأ المطلق التيار إلى 7٪ عند 43 مللي أمبير ، بينما كانت أعلى قيمة  خطأ مطلق لمقياس القدرة على النطاق  الكامل عند 5.8٪.
High Transaction Rates Performance Evaluation for Secure E-government Based on Private Blockchain Scheme
Authors: Kadhm Osama Ibraheem , Hamad Ali Hussein , Saeed Fahad
Published: September 2023

The implementation of technology in the provision of public services and communication to citizens, which is commonly referred to as e-government, has brought multitude of benefits, including enhanced efficiency, accessibility, and transparency. Nevertheless, this approach also presents particular security concerns, such as cyber threats, data breaches, and access control. One technology that can aid in mitigating the effects of security vulnerabilities within e-government is permissioned blockchain. This work examines the performance of the hyperledger fabric private blockchain under high transaction loads by analyzing two scenarios that involve six organizations as case studies. Several parameters, such as transaction send rate, blockchain size, batch timeout, organization number, and the number of clients, were modified in the two scenarios. The gradual addition of organizations was also observed to determine the impact of multi-organization on the throughput, latency, and scalability of the system. By increasing the block size to approximately 100 transactions per block, acceptable performance and latency results are attained. The throughput and latency findings are accepted for three or four organizations, but when many organizations are added, throughput and latency begin to suffer from poor performance. Also, many tests show that increased block timeout for high sending rates positively affects the throughput and latency.
Efforts and Support of Digital Literacy Program Development by Student Real Work Lecture Program to Improve the Quality of Human Resources of Digital Technology Use
Authors: Dhianawaty Diah , Dwiwina Resti Gradia , Achadiyani
Published: September 2023

The impact of the COVID-19 outbreak has caused learning activities to be carried out by utilizing information technology. The ability to use information technology during the COVID-19 era was being developed to increase people’s ability to utilize digital technology through digital literacy programs. The digital literacy program socialization was carried out in the following steps. Initially, the team members received work direction from the Directorate of Informatics Empowerment team of the Ministry of Communication and Informatics, Republic of Indonesia. Then, the team members met the Village Head and his staff to introduce the digital literacy program and ask for permission and support for this program. Afterward, the team member met the heads of the Youth organization and Junior high school and asked permission to socialize digital literacy with their members and the students. The digital literacy program was socialized to two groups: the young community in Mekarwangi village, members of Youth organizations, and Junior high school students. The total number of each group was 19 participants from Youth organization members and 191 participants from Junior high school students. All participants were educated on four pillars: digital ethics, digital safety, digital skills, and digital culture. The total number of participants was 210, have improved their skills and knowledge. They should care about digital skills, security, ethics, and culture. It was expected that in the future, participants would be able to implement the four main pillars and become qualified users of digital technology.
Influence of Geo-Technologies Integration on the Learning of Geography among Public Secondary Schools
Authors: Wakhungu Luke Nato
Published: September 2023

Technology integration has become critical globally in pursuit of transforming education. In Siaya County, a persistent dismal mean of scores in Geography subjects among public secondary schools from 2016-2022 at Kenya Certificate of Secondary Examination has been blamed on the learning approaches. The data from the seven sub-counties indicated that very little learning occurred. Further, no known study has addressed rote learning in Geography using an explanatory research design about Siaya County. The study sought the influence of integrating geo-technologies on learning in Geography among public secondary schools in Siaya County. This study focused on Geo-technology integration influencing learning among public secondary schools in Siaya County, Kenya. The objective that guided this study was to explore the influence of a geo-technology integrated classroom environment on learning Geography among public secondary schools in Siaya County, Kenya. The study sought to answer the question; during 2016-2022, how did the integration of geo-technology in the classroom environment influence the learning of Geography in public Secondary Schools in Siaya County? The study adopted interviews, questionnaires, and observational checklists to collect data. The study employed social cognitive constructivism theory to envision effective learning. The study sampled 102 respondents from 262 public secondary schools based on Krejcie and Morgan’s table. The choice of Siaya County was based on the fact that it is the only county in the larger Nyanza where technology integration was piloted by New Partnership for Africa’s Development (NEPAD) for quality learning. This study employed a mixed method and explanatory design to carry out the study. The study adopted interviews, questionnaires, and observational checklists to collect primary and secondary data.
ANTIOXIDANT AND INHIBITORY EFFECT OF SELECTED GHANAIAN VEGETABLES ON NITRIC OXIDE EXPRESSION IN LIPOPOLYSACCHARIDE-INDUCED MACROPHAGE CELLS
Authors: OFORI-ATTAH EBENEZER , ANING ABIGAIL , GORDON ANDREW , APPIAH-OPONG REGINA
Published: September 2023

Objective: Nitric oxide (NO) is a signaling molecule that plays a key role in the pathogenesis of inflammation. Inhibitors of NO may be useful candidates for the treatment of inflammatory diseases. The study aimed to determine the antioxidant and inhibitory effect of commonly used Ghanaian vegetables, namely Corchorus olitorius (CO), Solanum melongena (SM), Solanum torvum (ST), Xanthosoma sagittifolia (XS) and Abelmoschus esculentus (AE) on NO expression in a Lipopolysaccharide (LPS)-induced RAW 264.7 macrophage cell line.
Methods: The cytotoxic effects of the vegetables on the cell line were determined using a tetrazolium-based colorimetric assay. The inflammatory activity was determined by measuring the inhibition of NO production in LPS-induced RAW 264.7 macrophage cells. Total antioxidant activity, total phenolic, flavonoid, and reduced glutathione contents were evaluated using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay, Folin-Ciocalteu, aluminium chloride, and O-Phthalaldehyde methods, respectively.
Results: Our results showed that CO and ST significantly inhibited NO production in a concentration-dependent manner with good cell viability. Solanum torvum also exhibited strong antioxidant activity (IC50= 0.466±0.23 mg/ml) with total phenolic content of 230.73±1.84 mg/g GAE, while CO showed high flavonoid content (291.45±2.14 mg/g QUE). Abelmoschus esculentus recorded the highest glutathione content (58.6 µg/g GSH. Saponins, alkaloids, tannins, terpenoids, and cardiac glycosides were present in all the samples except SM and AE, which lacked terpenoids.
Conclusion: These findings suggest that CO and ST possess anti-inflammatory and antioxidant activities that could be explored as potential therapeutic remedies for inflammatory disorders.
AIF-1 GENE AS STRONG PROGNOSTIC BIOMARKER FOR ORAL CANCER
Authors: TANDON DIVYA
Published: September 2023

Objective: Oral Squamous Cell Carcinoma (OSCC), which is the sixth most prevalent type of cancer across the globe caused by cigarette smoking, smokeless tobacco use, excessive and extreme alcohol use, oral trauma, HPV (Human Papilloma Virus) infection as well as genetic mutations. AIF-1(Allograft Inflammatory Factor) has been identified as an inflammatory response modulator, and its increased expression has been linked to carcinogenesis.
Methods: In this study, 200 OSCC patients and 200 matched controls were compared to investigate if there was any association between the AIF-1(Allograft Inflammatory Factor) gene and the risk of cancer of oral cavity in the North Indian population. AIF-1(Allograft Inflammatory Factor) gene polymorphism rs2857595 were detected using TaqMan probe assay.
Results: The findings of our study revealed that AA genotype of AIF-1(Allograft Inflammatory Factor) Gene increases the susceptibility of Oral Squamous Cell Carcinoma. The association of AA genotype with Oral Squamous Cell Carcinoma is more in co-dominant model and the combination of both the mutant genotypes (AA+AG) is more significantly associated with Oral Squamous Cell Carcinoma in recessive model. GG genotype of AIF-1 (Allograft Inflammatory Factor) gene comes out with a protective effect against the risk of (OSCC Squamous Cell Carcinoma). To further understand the role of AIF-1(Allograft Inflammatory Factor) polymorphism, we compared the association of genotypes with various clinicopathological characteristics of Oral Squamous Cell Carcinoma patients. And we found that the patients with AA genotype have a significantly higher risk of developing high-grade tumors and more nodal involvement.
Conclusion: Thus, rs2857595 locus AA genotype of AIF-1(Allograft Inflammatory Factor) can be considered as important point in the development of accurate preventive approach and a prognostic indicator for oral cancer.
CLINICAL PROFILE AND TREATMENT RESPONSE TO SOFOSBUVIR-VELPATASVIR REGIMEN AND ITS IMPACT ON THE QUALITY OF LIFE IN CHRONIC HEPATITIS C PATIENTS
Authors: SINGH AJIT PRATAP , ASATI PANKAJ , YADAV KANISHK
Published: September 2023

Objective: Chronic Hepatitis C infection is one of the major global contributors to liver-related morbidity and mortality. Successful antiviral therapy with the direct-acting antiviral combination sofosbuvir-velpatasvir has shown to improve survival, liver-related outcomes, all-cause mortality, and even reverse fibrosis. We evaluated the treatment response of this regimen in terms of its impact on the Quality of life of patients during and after the therapy.
Methods: This is an Observational, prospective, descriptive study of serologic HCV RNA-positive cases. Data on change in clinical, biochemical profile, and quality of life using 2 standardized questionnaires SF-36 and CLDQ was analyzed at baseline, 12 w from baseline, and 24 w after therapy cessation.
Results: 62 out of the 87 patients registered during the study completed the desired study duration. 95% achieved sustained virological response (SVR) at 12 w and 100% at 24 w from baseline. Improved clinical profile with symptom resolution and change in the biochemical parameters and quality-of-life scores was statistically significant (P value-<0.001 and 0.005) at 12 w from baseline and 24 w after therapy cessation, respectively.
Conclusion: Patients achieving SVR with sofosbuvir-velpatasvir have been shown to improve clinical profile with normalization in biochemical markers of liver disease, which is reflected in all the quality-of-life domains of SF-36 and CLDQ-HCV. However, long-term follow-up with larger sample size is required for improved study validity and to improve long-term liver-related outcomes.
DEVELOPMENT AND VALIDATION OF NOVEL UV-VISIBLE SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TEPOTINIB IN BULK AND IN PHARMACEUTICAL FORMULATION
Authors: SHIRWAR MONIKA , BIRAJDAR SHUBHANGI , GARAD SHRUTI , KUMBHAR SMITA
Published: September 2023

Objective: The objective of the study is to develop a new, simple, rapid, accurate, and economical UV-spectrophotometric method and validate the same for the estimation of Tepotinib in bulk and in pharmaceutical formulation as per ICH guidelines.
Methods: The present work was carried out using the UV-Visible double-beam spectrophotometer model Systronics 2201. Tepotinib was found soluble in water, methanol, methanol so, analytical-grade methanol was used as a solvent for conducting the work. The λmax of the tepotinib was determined by dissolving pure drug in methanol scanned in the range of 200-800 nm. The present method was validated for the linearity, accuracy, precision, Limit of Detection and Limit of Quantification.
Results: The maximum absorbance of tepotinib obtained at a wavelength of 272 nm. The method was found linear in the range of 3-15 µg/ml with the regression coefficient of 0.996 and the equation y = 0.0699x+0.0335. The accuracy was found to be in the range of 96.8-98.5%, the intra-day and inter-day precision % RSD value was 0.262 and 0.69, respectively and the LOD and LOQ were 0.0925 µg/ml and 0.28 µg/ml respectively.
Conclusion: The method demonstrated good reproducibility and recovery so, proposed method can be successfully applied for the routine analysis of tepotinib in bulk and pharmaceutical dosage form.
INVESTIGATING THE EVOLUTION OF OPTIMAL PRODUCT AVAILABILITY FOR PUBLIC HEALTH PROGRAMS IN KATSINA STATE, NIGERIA
Authors: GULMA KABIRU ABUBAKAR
Published: September 2023

Objective: This study aimed to explore the evolution of the availability of public health commodities across all the supported health facilities in Katsina State, northwestern Nigeria.
Methods: To achieve this, Quarterly Stock Status Reports (QSSR) were produced from the analysis of the Logistics Management Information System (LMIS) reports of facilities, local government stores, and central stores of all the public health programs in the state from April 2017 to March 2018 (one year). Analyses entailed computing the Month of Stock (MoS) for all commodities by dividing their Stock on Hand (SoH) by the Average Monthly Consumption (AMC). The product availability for the following public health programs was assessed for four consecutive quarters (Apr.-Jun. 2017, Jul.-Sep. 2017, Oct.-Dec. 2017, and Jan.-Mar. 2018)-HIV/AIDS, tuberculosis, malaria, reproductive health/family planning (FP), routine immunization, nutrition, Neglected Tropical Diseases (NTD), Maternal, Newborn, and Child Health (MNCH), and the state’s Free Medicare Scheme (FMS).
Results: The one-year trend provided a precise representation of the commodity security of each public health supply chain across various programs within the state. While only one program (routine immunization) recorded 100% all-time product availability, TB appeared to be the most stable (95% of products in optimal quantities) of all the assessed public health programs employing MoS as a performance measure. It is important to note that nutrition, neglected tropical diseases, and the Free Medicare scheme did not operate with MoS as a measure of stock status but recorded product availability of 78.5%, 80%, and 84.6%, respectively.
Conclusion: There is a necessity for periodic stock assessment across all public health programs for other states to establish accurate stock positions and identify programs that require enhanced logistical and supply chain technical support.
ANTIOXIDANT AND ANTI-SICKLING ACTIVITY OF EXTRACTS FROM THE STEM AND ROOTS BARKS OF STRYCHNOS INNOCUA (DEL.)
Authors: BRUKUM MAWATE FLORANCE , KPEGBA KAFUI , EVENAMEDE KODJO SELOM , AGBONON AMEGNONA , SIMALOU OUDJANIYOBI
Published: September 2023

Objective: In Togo Strychnos innocua represents a plant traditionally used to cure sickle cell disease. This study aims to carry out a phytochemical study and evaluate the antioxidant and anti-sickling activity of Strychnos innocua root and stem barks to support its use.
Methods: Hydroethanolic and ethanolic extracts of each plant organ were obtained by maceration. Polyphenol content was determined using the Folin-Ciocalteu’s reagent and the flavonoid content using Aluminium trichloride (AlCl3) method. The anti-sickling activity of hydroethanolic extracts of root and stem barks was tested on SS blood samples from sickle cell patients using the Emmel test. Antioxidant activity was assessed by DPPH and FRAP methods on both the hydroethanolic and ethanolic extracts.
Results: Results indicate that the highest levels of polyphenols were measured in the hydroethanolic extract of the root barks (59.32±1.77 mg GAE/g) and the ethanol extract of the stem barks (98.27±2.44 mg GAE/g). The hydroethanolic extract of the root barks and the ethanolic extract of the stem barks showed high levels of flavonoids. Extracts from both organs significantly reduced falciformation (p<0.001) at a rate of 22% (root) and 35% (stem) compared with the control (94%). In addition, root and stem extracts showed slight antioxidant activity.
Conclusion: Results justify the traditional use of Strychnos innocua roots in treating sickle cell anaemia.
SYNTHESIS OF UREA AND MAGNETITE-BASED CHITIN AS ADSORBENTS FOR THE REMOVAL OF AMLODIPINE BESYLATE
Authors: LONDONO CESAR , BARRERA KELLY , ROJAS JOHN
Published: September 2023

Objective: Development of urea and magnetite-based chitin adsorbents for the removal of amlodipine besylate.
Methods: Amlodipine is a calcium channel blocker widely used to treat hypertension and angina. However, it is important to treat the residues before disposal so they do not pollute the effluent water sources. The amlodipine sorption property of chitin-based subtract (CBS) was improved by treatment with magnetite and urea, followed by pyrolysis at 500 °C. The FT-IR characterization, elemental composition, pore properties, and sorption isotherms were also assessed.
Results: The sorption capacity of amlodipine increased from 4.6 to 9.3 mg/g for the urea and magnetite-treated products, respectively. Further, modified chitin products showed a pore volume (micro and mesopore composition), pore percentage, and roughness of 0.01 cm3g-1, 0.02 cm3g-1, 32% and 68%, and 1.2, respectively. The CBS and derivatives did not present Langmurian behavior, indicating a characteristic heterogeneous surface and the presence of energetically distinct sorption sites. The sorption equilibrium was achieved within 5 min, resulting in a net physical sorption.
Conclusion: The insertion of nitrogen and iron moieties on the surface of chitin improved the adsorption capacity of amlodipine.
“I'm yours, and I'm not yours”: Reinventing the Genesis of Creation in a Posthuman World
Authors: Noor Sifatun
Published: September 2023

The aim of this study is to discuss and examine the film Her, in relation to the story of Genesis. This will allow us to study the concept of humans from the inception to the contemporary world and address how women as the ‘other’ have always been excluded from that category. The emergence of AI, machines, or cyborgs as the new social entities in the context of posthumanism, as portrayed in the film manages to widen the border of the exclusive category of ‘human’ and helps women to build a place for themselves within it. In addition, the relationship between Theodore and Samantha contradicts the typical relationship of the male-dominated world and finds similarities with the story of Adam and Eve and their creation. The study uses the film, Her, to develop the argument that the posthuman approach is an ideal path to stretch the borders of the category of ‘humans’ and make it more inclusive.
Talking about Rural Environments, Education and Sustainability: Motives Positions and Practice of Grassroots Organizations
Authors: García-Romero David , Portela Cristina Varela , Peixoto Ana
Published: September 2023

The ecosocial crisis we are involved in for the last decades demands an urgent change in the way human being deals with nature. Arguably, the hegemonic economic system cannot continue the same for long, since it entails a kind o colonialism that exploits land, communities, and natural resources beyond the possibilities of restoration. It is also arguable that western positivist science has contributed to this system, both justifying productivity over sustainability and creating a symbolic distance with colonized Peoples all around the globe, justifying therefore the exploitation of the land. It has been defended the need for an epistemological dialogue with agents that directly manage the territory, as those of the countryside. This work starts a common path that is purposed for grassroots organizations from rural environments and higher educators based on service-learning. We aim to analyze the motives, positions, and cultural practices of those grassroots organizations. We have performed two focus groups on videoconference, with 15 participants from 14 organizations. Topics on the relationship between education, sustainability, and the rural environment where discussed and recorded to inductive-deductive content analysis. The study was open to the participation of people from the organizations in the whole research process. In the discussion, we can see a critic to an educational system at the service of the hegemonic economic system, as well as a purpose for the naturalization, humanization, and diversification of both the economic and educational systems. The rural environment appears as a field of opportunity to develop practices of interdependence and ecodependence.
A Critical Review on the Potency of Phytoconstituents in the Management of COVID-19
Authors: Raman Kannan , Rajagopal Kalirajan , Swaminathan Gomathi , Jupudi Srikanth , Dhama Kuldeep , Barua Rashu , Emran Talha Bin , Osman Hamid , Khandaker Mayeen Uddin
Published: September 2023

Natural products and their derivatives have traditionally been used as a source of therapeutic agents. Their beneficial properties are due to large varieties in their chemical structures and biochemical actions. The discovery of natural products such as phytoconstituents have crucial role in the development of less toxic and more effective drugs. Phytoconstituents have shown to be beneficial in treating viral diseases such as the previous chikungunya virus, hepatitis C virus, SARS, and MERS viral diseases. Flavonoids, alkaloids, terpenoids, and other group of compounds combat against COVID-19 in several ways like by protease inhibition, spike protein inhibition, Nrf2 inhibition. The accumulation of NRF2 inhibits the development of the SARS-CoV-2 virus and stimulates anti-inflammatory action. The present review highlights the therapeutic importance of compounds isolated from medicinal plants and/or herbs, such as crude extracts of Curcumin I-III, Leptodactylone, Ginsenoside-Rb1, Lycorine, Reserpine, Saikosaponin B2, Cepharanthine, Withanoside V, Gingerol, Piperanine, chromans, flavonoids, Amentoflavone etc. against SARS-CoV-2. Natural products are typically safe, stable, and dependable source for finding drugs to control the current pandemic. Antiviral secondary metabolites many medicinal plants have given ingredients that were isolated. The selected plants based phytoconstituents may potentially be used against viruses’ development on anti-SARS-CoV-2 to offer a reference point in this field.
Biodesulfurizing Microbes in the Petroleum Refinery Areas of Saudi Arabia
Authors: Ahmad Abrar , Baothman Othman A. , Nadeem Muhammad Shahid , Ahmad Varish
Published: September 2023

Gordonia sp., Rhodococcus, Paenibaccilus, Mycobacterium and many other desulfurizing strains have shown good potential for dibenzothiophene (DBT), 4, 6-Dimethyldibenzothiophene (4-6-Dimethyl dibenzothiophene) and other organosulfur biodesulfurization. These are microbes which have 4S pathway to remove S from remaining calcitarant organosulfur compounds even after deep desulfurization. Sulfur compounds present in crude oils, diesel and petrol when combust in engines they emerge out in the form of elemental Sulfur, which causes environmental and health problems. Therefore, efforts are going to remove this Sulfur compounds by Hydrodesulfurization (HDS) treatment. Some organosulfur compounds remain there even after HDS, which can only remove by highly evolved microbes residing nearby petroleum-contaminated areas in refineries zone. Nature has such adopted and evolved microbes for the bioremediation of such toxic substances. Here we have isolated and characterized highly evolved and adopted Biodesulfurizing microbes present around oil refineries in Kingdom of Saudi Arabia and prepare the culture collection of such highly evolved and adopted biodesulfurization microorganisms for future application of applied Industrial petroleum refineries, which can reduce the Sulfur load in the petroleum products. The several (10 different types) microbes have been reported in these soils to grow in sulfur compounds. Out of these microbes one microbe desulfurizes by 4S pathway. It was identified to be Rhodococcus erythropolis type named as Rhodococcus erythroplis KAU10. They show good potential for various organosulfur compounds (DBT, 2,4,6-Trimethyl Benzothiophene, Benzothiophene, Dibenzyl sulfide, Benzonaphthothiophene, Dibenzothiophene sulfone, along with crude oil and Petrol and Diesel. Isolated strain Rhodococcus erythroplis KAU10 have good potential for Biodesulfurization.
Exploring the Potential of Bacillus velezensis, an Endophytic Bacteria Isolated from Alternanthera philoxeroides for Plant Growth Promotion and Bioremediation Properties
Authors: Philip Indhu , Sarojini Suma , Biswas Soma , Jayaram Saranya
Published: September 2023

The current work was done to analyse the bioremediation and plant growth promotion (PGP) traits of endophytic bacteria isolated from Alternanthera philoxeroides from Bellandur Lake, Bangalore, India. Twenty-nine endophytic bacteria were isolated and tested for their PGP traits like indole acetic acid (IAA), ammonia, nitrogen fixation, 1-aminocyclopropane-1- carboxylate (ACC) deaminase production, phosphate solubilization etc. Endophytic bacterium, BEBAphL1 obtained from leaves of A. philoxeroides exhibited significant plant growth promotion properties and the isolate was identified as Bacillus velezensis OQ874364 using 16S rRNA sequencing. The bacterium showed potential IAA, ammonia production, nitrogen fixation, phosphate solubilization, and ACC deaminase production. The results indicate that this endophyte is promising as a growth-promoting inoculant, reducing the reliance on chemical inputs in conventional agricultural practices while enhancing nutrient uptake and stress resilience in plants. B. velezensis exhibited tolerance to high levels of chromium (500 mg/L) and NaCl (15%) and was also able to decolourize Congo red by 70% at 0.005% concentration of dye. Characterization of dye samples pre- and post-bacterial treatment was done using Fourier-transform infrared spectroscopy (FTIR) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis. The findings of the study indicate that B. velezensis shows promise as a plant growth stimulator capable of withstanding heavy metal exposure and breaking down dyes.
Improvement in Power Quality of Grid Connected PV & Wind Power Generation Systems
Authors: Wasnik Ashwini , Malwar Nikita , Ghutke Pratik
Published: September 2023

Abstract: The small turbine shows the connection of the source. This system, also used by remote and off-network systems, is known as a crossover power system. It uses wind energy from wind turbines to provide the mechanical ability to convert to electrical force. Regarding cost, efficiency, and dependability, combining at least two sustainable power sources is preferable to using just one. n terms of cost, efficiency, and dependability, a combination of at least two sustainable power sources is superior to one. The most important component for every country's contemporary and agricultural progress is energy
Healthcare: A Growing Role for Large Language Models and Generative AI
Authors: Pahune Saurabh , Rewatkar Noopur
Published: September 2023

Abstract: Large language models and generative artificial intelligence (GAI) have recently demonstrated significant promise for revolutionizing a range of industries, including healthcare. The paper investigates how these cutting-edge AI developments are transforming healthcare applications. We focus on how big language models, like GPT-3 (generative pretrained transformer), Visual ChatGPT and generative AI, such Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs), can be applied to solve important problems in the healthcare sector. Medical text analysis is one of the main uses of massive language models in the visual ChatGPT healthcare industry. These models have impressive natural language processing abilities that make it possible to effectively extract important information from electronic health records (EHRs), biomedical text data from large biobanks, scholarly articles and patient notes. The Biomedical Transformer Model represents a ground-breaking development in natural language processing for the biomedical field, exhibiting outstanding performance in comprehending and producing textual data. It opens up new avenues for biomedical research, diagnosis, and personalized therapy when combined with Multimodal Biomedical AI, which makes use of numerous data sources, including pictures, genomes, and clinical records. On the other side, generative AI has made great progress in medical picture analysis such as MRI scans and X-rays. The outstanding performance of GANs in medical picture synthesis and augmentation has helped to increase the precision and accuracy of diagnosis. Due to the issues with small and uneven medical datasets, VAEs have proven crucial in producing realistic medical images for training and research reasons. In addition to describing the various generative AI tools used in healthcare, this paper also provides an overview of multimodal medical LLMs and the biomedical transformer LLMs in the healthcare industry. Large language models and generative AI have great potential, but ethical issues and data privacy are still major problems in healthcare applications. Further, we investigate the potential role of multimodal medical LLMs as the foundation for novel assistive technologies in the fields of professional medicine, medical research, and consumer applications in the healthcare industry
From YouTube Comments to Insights: A Sentiment Analysis of Opinions on Productivity Tools
Authors: Shah Devang , Parekh Masumee
Published: September 2023

Abstract: YouTube, a diverse content hub, acts as a prominent platform for both viewing videos and engaging through comments that express opinions. By carefully analyzing these comments, sentiments associated with products or topics become evident. This research delves into sentiment analysis of YouTube comments, specifically focusing on sentiments towards productivity tools and technologies. Through this examination of conveyed sentiments, it deepens understanding of public perceptions and attitudes toward these tools. Utilizing YouTube's reach and engagement, the study systematically collects comment data using the YouTube API and employs the established VADER sentiment analysis framework. Employing a Bag-of-Words approach, the research incorporates machine learning algorithms like Naive Bayes and Random Forest, achieving accuracy rates of 84.01% and 91.34%, respectively. In-depth temporal analysis of user engagement patterns uncovers trends, with heightened engagement followed by decline, correlating with external events, notably the Covid-19 pandemic. These insights enhance sentiment analysis and illuminate dynamics between societal occurrences, user sentiments, and digital dialogues, offering perspectives on evolving opinions about productivity tools and technologies
Development of the "Al-muhdastah Al-yaumiyyah" Textbook to Improve Arabic Speaking Skills at an Islamic Boarding School
Authors: Yasin Agus , Marheni Br Maha  , Fahrurrozi  , Ahmad Hidayatullah Zarkasyi  , Siti Anne Barkah Nur Fauziah  , Ahmad Zalzuli
Published: September 2023

This study aimed to improve Arabic speaking skills textbooks which were developed in such a way that interactive exercises and topics were adapted to the student’s language by adding appropriate vocabulary and pictures to the learning material. This research was used as a template for ADDIE's research and development (R&D). The study sample was first-grade students at the Mawaridussalam Islamic Boarding School, with class 1C (30 students) used to assess student interest and the textbooks’ effectiveness. The data were collected by observations, interviews, and tests before qualitative and quantitative analyses. The significance of the average student’s test score after using the designed textbook (80.50) was higher than the average score before using the textbook (59.17) to learn Arabic speaking skills. These results confirmed that the proposed educational approach is practical, simple, and attractive.
Material Development as the Dominant Students Research Topic of the Arabic Language Education at the Doctoral Programme
Authors: Rosyidi Abdul Wahab , Sari Risna Rianti , Faisal Mahmoud Adam  , Fathoni Ahmad
Published: September 2023

The aim of this study was to classify the results of the dissertation, describe the research method, and present the final findings. The research method used descriptive analysis with the main dissertation data for 2012–2022, using the Milles and Huberman model analysis technique. The research result was that the focus of the dissertation study spread to ulum al-lughah and maharah al-lughah; however, it swelled to the development of teaching materials. The dissertation was written using qualitative and quantitative research models, with the type of R&D development model adapted by Borg and Gall as the majority. The final dissertation formulation looked at the characteristics of the teaching materials in each approach, theory, and frame used. For the feasibility of teaching material products at a feasible level and effectively improving language skills and knowledge. From the results of the assessment, there was no expert validation, which showed low results, and the effectiveness test failed.
Exploring Muhammadiyah Generation Z Perpectives Toward Halal Cosmetics
Authors: Alam Adha Mufti , Rahmatia Alfina , Puspita Anggraeni Sisilia , Millania Annisa
Published: September 2023

Nowadays, halal cosmetic gets popular among young generation, especially generation Z as an internet generation. It made Indonesia as the second largest expenditure on halal cosmetic in the world on 2017 in which the Muslim generation Z becomes the market target. Owing to such interests, the main objective of this study is to explore the perspectives of Muhammadiyah generation z toward halal cosmetics in Indonesia. The study uses qualitative methode through literature study and in-depth interview with convenience sampling method in which the interview data use Nvivo 12 application and descriptive analysis. The result from literature study based on Nvivo 12 analysis shows that religiosity value, health factor, and halal cosmetics marketing strategy are playing a role to the perspectives of Muslim generation Z toward halal cosmetics.
Fatores associados ao início precoce do aleitamento materno em crianças menores de 2 anos
Authors: Velho Caroline Farias , Saldan Paula Chuproski
Published: September 2023

O aleitamento materno logo após o parto está associado à redução da mortalidade neonatal e infantil e à maior duração do aleitamento materno exclusivo. O objetivo deste estudo foi analisar os fatores associados ao início precoce do aleitamento materno em crianças menores de 2 anos de idade. Este estudo transversal foi conduzido durante a Campanha Nacional de Vacinação contra Poliomielite de 2012, em Guarapuava (PR), por meio de aplicação de questionário estruturado. Para identificação dos fatores, foram construídos modelos de regressão de Poisson, obtendo-se razões de prevalências em modelos bivariados e múltiplo. Mantiveram-se no modelo final as variáveis que apresentaram p < 0,05. A prevalência do aleitamento materno precoce foi de 78,54%, e os fatores associados ao não início do aleitamento materno precoce foram: criança do sexo masculino, baixo peso ao nascer, não nascer em hospital/maternidade e parto cesáreo. Idade materna entre 20 e 34 anos foi fator de proteção para o início precoce do aleitamento materno. É importante analisar os fatores de cada município para que, assim, sejam propostas ações efetivas direcionadas a serviços e profissionais de saúde e às mães.
Acesso dos usuários do SUS à atenção psicossocial nos municípios brasileiros
Authors: Silva Stefany Costa , Oliveira Luciane Cristina Feltrin de
Published: September 2023

A criação do Sistema Único de Saúde (SUS) sob influência do movimento da Reforma Psiquiátrica propôs um novo modelo para a atenção à saúde mental focado na Atenção Primária em Saúde (APS). Porém, a mudança do modelo de atenção ainda possui algumas barreiras de acesso dos usuários aos serviços de saúde. Esta pesquisa busca analisar a produção científica sobre o acesso dos usuários do SUS à atenção psicossocial. Trata-se de uma revisão integrativa, na qual foram usados os descritores: “acesso aos serviços de saúde” “atenção primária à saúde”, “serviços de saúde mental” nas bases de dados da SciELO, Medline/PubMed e Lilacs, resultando na inclusão de 13 estudos. Os dados foram analisados de acordo com a análise temática de conteúdo, constituída pela pré-análise, pela exploração do material e pelo tratamento dos resultados obtidos/interpretação. Os resultados evidenciaram como a APS tem articulado o acesso à atenção psicossocial, bem como as dificuldades que enfrenta no uso das tecnologias leves para o manejo de transtornos mentais e sofrimento psíquico. E, no campo da atenção secundária e no acesso aos serviços da atenção psicossocial, existem dificuldades estruturais, físicas e sociais. Além disso, evidenciam-se lacunas na produção acerca do acesso às diferentes modalidades dos Centros de Atenção Psicossocial e das residências terapêuticas. Assim, apesar do direito à saúde conquistado e da reorientação do modelo de atenção à saúde mental com foco na APS, esse nível de atenção ainda não consegue ser resolutivo.
Analysis of schistosomiasis cases and deaths in Brazil: epidemiologic patterns and spatio-temporal distribution, 2010-2022
Authors: De Oliveira Vinícius José , De Jesus Thiago Alves , Silva Bianca de Jesus e , Borges Fernanda Vianna , Borges Allyne Silveira , Gomes Wytter Rodrigues Velasco
Published: September 2023

Schistosomiasis is a parasitic infection caused by a group of flatworms called Schistosoma. The disease is primarily found in developing countries, especially in rural areas with poor sanitation and limited access to clean water. Schistosomiasis is transmitted by contact with contaminated freshwater, such as rivers, lakes, and ponds, where the parasites’ larvae live. The aim of this article was to analyze the epidemiological variables of schistosomiasis cases (2010-2022) and deaths (2010-2020) in Brazil. This is a cross-sectional, descriptive, and quantitative epidemiologic study. The methodological strategy involved the analysis of epidemiological bulletins provided by the Sistema de Informação de Agravos de Notificação (SINAN) and the Sistema de Informação sobre Mortalidade (SIM) from 2010 to 2022. There were 93.521 reported cases of schistosomiasis and 5.495 deaths due to complications of this infection. The intestinal form was the most identified. Minas Gerais, São Paulo, Bahia, and Espírito Santo were the states with the highest prevalence of the disease. Males, of mixed race, aged between 20 and 39 years, and with a low level of education were the most affected. There were 732 cases of infection in pregnant women. Furthermore, 62.56% of the cases evolved to cure and 5.88% evolved to death by the notified disease. In conclusion, it is crucial to adopt prevention measures and access to education to effectively combat schistosomiasis.
Il dipinto di Teodoro Matteini con Angelica e Medoro nella Glittica
Authors: Tassinari Gabriella
Published: September 2023

The difficulty of representing the paintings in the gems has determined their lesser success in the glyptic repertoire compared to the representation of the sculptures. However, the engravers received a successful painting, such as the one painted by Teodoro Matteini in 1786: Angelica and Medoro carving their names on the bark of a tree, scene from the Orlando Furioso of Ariosto. This study analyzes the reproduction of the painting in the glyptic. The image appears on high quality intaglios and cameos by famous engravers, such as Giovanni Beltrami, Clemente Pestrini, Domenico Calabresi, who sometimes make variations to the composition; on anonymous gems, and in shell, cheaper material. A cameo mounted on the lid of a box / snuffbox in Ischia’s lava, a fashionable vehicle for the transmission of messages, testifies to the intense diffusion and circulation of Matteini’s painting.
Das Hin und Her der Blicke, Eidola in der Pupille Augenförmiger Gemmen
Authors: Weiss Carina
Published: September 2023

The presented group of late Republican to early Imperial intagli consists of round layered stones (sardonyx, cornelian onyx) with a flat reverse side, which are strongly convex on the front side. Their horizontally stacked and differently coloured plies are sanded on the front to form concentric rings around a dark centre. The motif incised in this centre looks like an eidolon in the pupil of a 'fisheye'. Most of these motifs can be interpreted against the background of Augustan love poetry. It is possible that gems of this kind were gifts of love and, due to their striking design as an eye, also had an apotropaic function.
Gagates
Authors: Mastrocinque Attilio
Published: September 2023

The jet stone was used for amulets from antiquity to modern times. Legends and beliefs concerning it flourished. It is black and, being similar to amber, could be burned to obtain a smoke used for magical and medical purposes. Some religious ceremonies used it for attracting snakes. It was often confused with other stones, such as aetites and serpentine and even with agate because it was also called antachates.
An Early Molecular Biomarker Study in Pre-eclampsia
Authors: Vijayan Vinaya , Kannan R. , Reddy B. Ram
Published: September 2023

Preeclampsia (PE), a hypertension condition associated with pregnancy that manifests after 20 weeks of pregnancy,may be brought on by faulty placental development and poses a serious risk to both the mother and the fetus. The disease can bedetected only once the symptoms arise, there is a need for a biomarker, which makes early detection of the disease possible, andproper management of the disease can be done at an early stage of pregnancy. Even though many studies were done globallyregarding the role of microRNAs as molecular biomarkers in pre-eclampsia, no literature showed the effect of microRNA inpreeclampsia in the Indian population. The aim of the study was to find an early molecular marker that can detect the disease atan early stage, even before the symptoms arise. Placental MicroRNAs were studied using Next-generation Sequencing of 60Preeclamptic groups ( 30 Early Onset,30Late onset preeclampsia), and 30 control groups were selected; miRNA profiling wasdone by Illumina sequencing, and the quantifier did downstream analysis for identification, quantification, and expression profiling.pl, script, and miRDeep2.pl, script. Total RNAs were extracted from placental tissues and cells by TRIzol reagent and purified. Therelative expression of miR-483-5p in tissues or cells was determined: micro-RNA 483-5p was expressed in significant quantity inEarly Onset preeclamptic placental samples compared to Late Onset and normal samples. miR 483-5p was analyzed, and the genetargets were found using computational methods. From this study, it was found that microRNA 483-5p can be used as an earlybiomarker for the identification of preeclampsia.