bluuebunny/crossref_metadata_2025 huggingface dataset:
Inter- and intraobserver reliability of morphological Mutch classification for greater tuberosity fractures of the proximal humerus: A comparison of x-ray, two-, and three-dimensional CT imaging
Authors: Razaeian Sam , Askittou Said , Wiese Birgitt , Zhang Dafang , Harb Afif , Krettek Christian , Hawi Nael
Published: November 2021

Background

The objective of this study was to investigate inter- and intraobserver reliability of the morphological Mutch classification for greater tuberosity (GT) fragments in consecutive proximal humerus fractures (PHF) regardless of the number of parts according to the Codman classification system for three different imaging modalities (plain radiographs, two-dimensional [2-D] computed tomography [CT], and reformatted, three-dimensional [3-D] CT reconstruction).

Materials and methods

One hundred thirty-eight consecutive PHF with GT involvement were identified between January 2018 and December 2018 in a supraregional Level 1 trauma center. GT morphology was classified by three blinded observers according to the morphological Mutch classification using the picture archiving and communication software Visage 7.1 (Visage Imaging Inc., San Diego, CA, USA). Fleiss’ and Cohens’ kappa were assessed for inter- and intraobserver reliability. Strength of agreement for kappa (k) values was interpreted according to the Landis and Koch benchmark scale.

Results

In cases of isolated GT fractures (n = 24), the morphological Mutch classification achieved consistently substantial values for interobserver reliability (radiograph: k = 0.63; 2-D CT: k = 0.75; 3-D CT: k = 0.77). Moreover, use of advanced imaging (2-D and 3-D CT) tends to increase reliability. Consistently substantial mean values were found for intraobserver agreement (radiograph: Ø k = 0.72; 2-D CT: Ø k = 0.8; 3-D CT: Ø k = 0.76). In cases of multi-part PHF with GT involvement (n = 114), interobserver agreement was only slight to fair regardless of imaging modality (radiograph: k = 0.3; 2-D CT: k = 0.17; 3-D CT: k = 0.05). Intraobserver agreement achieved fair to moderate mean values (radiograph: Ø k = 0.56; 2-D CT: Ø k = 0.61; 3-D CT: Ø k = 0.33).

Conclusion

The morphological Mutch classification remains a reliable classification for isolated GT fractures, even with 2-D or 3-D CT imaging. Usage of these advanced imaging modalities tends to increase interobserver reliability. However, its reliability for multi-part fractures with GT involvement is limited. A simple and reliable classification is missing for this fracture entity.
Cloning, expression and characterization of metalloproteinase HypZn from Aspergillus niger
Authors: Song Peng , Xu Wei , Wang Kuiming , Zhang Yang , Wang Fei , Zhou Xiuling , Shi Haiying , Feng Wei
Published: November 2021

A predicted metalloproteinase gene, HypZn, was cloned from Aspergillus niger CGMCC 3.7193 and expressed in Pichia pastoris GS115, and the physicochemical characteristics of recombinant HypZn were investigated after separation and purification. The results showed that the specific activity of the purified HypZn reached 1859.2 U/mg, and the optimum temperature and pH value of HypZn were 35°C and 7.0, respectively. HypZn remained stable both at 40°C and at pH values between 5.0 and 8.0. The preferred substrate of HypZn was soybean protein isolates, and the Km and Vmax values were 21.5 μmol/mL and 4926.6 μmol/(mL∙min), respectively. HypZn was activated by Co2+ and Zn2+ and inhibited by Cu2+ and Fe2+. The degree of soybean protein isolate hydrolysis reached 14.7%, and the hydrolysates were of uniform molecular weight. HypZn could tolerate 5000 mM NaCl and completely lost its activity after 30 min at 50°C. The enzymological characterizations indicated that HypZn has great application potential in the food industry, especially in fermented food processing.
Genome-wide survey and characterization of transcription factors in the silk gland of the silkworm, Bombyx mori
Authors: Ma Yan , Sun Qiwei , Huang Lihua , Luo Qin , Zeng Wenhui , Ou Yao , Ma Jingwen , Xu Hanfu
Published: November 2021

Transcription factors (TFs) are key proteins that modulate gene transcription and thereby lead to changes in the gene expression profile and the subsequent alteration of cellular functions. In the silk gland (SG) of silkworm Bombyx mori, an important silk-producing insect, TFs are of vital importance in the regulation of silk protein synthesis in this organ. However, which TFs exist and express in the SG remains largely unknown. Here, we report the large-scale identification of TFs in the SG based on available full-length transcript sequences and the most recent version of silkworm genome data. In total, 348 candidate TFs were identified by strict filtration and were classified into 56 TF families. Chromosomal distribution, motif composition, and phylogenetic relationship analyses revealed the typical characteristics of these TFs. In addition, the expression patterns of 348 TFs in various tissues of B. mori, especially the SG of fourth-molt (4LM) and day-3 and day-4 fifth-instar (5L3D and 5L4D) larvae, were investigated based on public RNA-seq data and gene microarray data, followed by spatiotemporal verification of TF expression levels by quantitative real-time PCR (qRT-PCR). This report describes the first comprehensive analysis of TFs in the B. mori SG. The results can serve as a baseline for further studies of the roles of TFs in the B. mori SG.
The PINK1—Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells
Authors: Bradshaw Aaron V. , Campbell Philip , Schapira Anthony H. V. , Morris Huw R. , Taanman Jan-Willem
Published: November 2021

Mutations in the PINK1 and PRKN genes are the most common cause of early-onset familial Parkinson disease. These genes code for the PINK1 and Parkin proteins, respectively, which are involved in the degradation of dysfunctional mitochondria through mitophagy. An early step in PINK1 –Parkin mediated mitophagy is the ubiquitination of the mitofusin proteins MFN1 and -2. The ubiquitination of MFN1 and -2 in patient samples may therefore serve as a biomarker to determine the functional effects of PINK1 and PRKN mutations, and to screen idiopathic patients for potential mitophagy defects. We aimed to characterise the expression of the PINK1 –Parkin mitophagy machinery in peripheral blood mononuclear cells (PBMCs) and assess if these cells could serve as a platform to evaluate mitophagy via analysis of MFN1 and -2 ubiquitination. Mitophagy was induced through mitochondrial depolarisation by treatment with the protonophore CCCP and ubiquitinated MFN proteins were analysed by western blotting. In addition, PINK1 and PRKN mRNA and protein expression levels were characterised with reverse transcriptase quantitative PCR and western blotting, respectively. Whilst CCCP treatment led to MFN ubiquitination in primary fibroblasts, SH-SY5Y neuroblastoma cells and Jurkat leukaemic cells, treatment of PBMCs did not induce ubiquitination of MFN. PRKN mRNA and protein was readily detectable in PBMCs at comparable levels to those observed in Jurkat and fibroblast cells. In contrast, PINK1 protein was undetectable and PINK1 mRNA levels were remarkably low in control PBMCs. Our findings suggest that the PINK1 –Parkin mitophagy signalling pathway is not functional in PBMCs. Therefore, PBMCs are not a suitable biosample for analysis of mitophagy function in Parkinson disease patients.
Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells
Authors: Adeniji Opeyemi S. , Kuri-Cervantes Leticia , Yu Chenfei , Xu Ziyang , Ho Michelle , Chew Glen M. , Shikuma Cecilia , Tomescu Costin , George Ashley F. , Roan Nadia R. , Ndhlovu Lishomwa C. , Liu Qin , Muthumani Kar , Weiner David B. , Betts Michael R. , Xiao Han , Abdel-Mohsen Mohamed
Published: November 2021

Siglec-9 is an MHC-independent inhibitory receptor expressed on a subset of natural killer (NK) cells. Siglec-9 restrains NK cytotoxicity by binding to sialoglycans (sialic acid-containing glycans) on target cells. Despite the importance of Siglec-9 interactions in tumor immune evasion, their role as an immune evasion mechanism during HIV infection has not been investigated. Using in vivo phenotypic analyses, we found that Siglec-9+ CD56dim NK cells, during HIV infection, exhibit an activated phenotype with higher expression of activating receptors and markers (NKp30, CD38, CD16, DNAM-1, perforin) and lower expression of the inhibitory receptor NKG2A, compared to Siglec-9- CD56dim NK cells. We also found that levels of Siglec-9+ CD56dim NK cells inversely correlate with viral load during viremic infection and CD4+ T cell-associated HIV DNA during suppressed infection. Using in vitro cytotoxicity assays, we confirmed that Siglec-9+ NK cells exhibit higher cytotoxicity towards HIV-infected cells compared to Siglec-9- NK cells. These data are consistent with the notion that Siglec-9+ NK cells are highly cytotoxic against HIV-infected cells. However, blocking Siglec-9 enhanced NK cells’ ability to lyse HIV-infected cells, consistent with the known inhibitory function of the Siglec-9 molecule. Together, these data support a model in which the Siglec-9+ CD56dim NK subpopulation is highly cytotoxic against HIV-infected cells even whilst being restrained by the inhibitory effects of Siglec-9. To harness the cytotoxic capacity of the Siglec-9+ NK subpopulation, which is dampened by Siglec-9, we developed a proof-of-concept approach to selectively disrupt Siglec/sialoglycan interactions between NK and HIV-infected cells. We achieved this goal by conjugating Sialidase to several HIV broadly neutralizing antibodies. These conjugates selectively desialylated HIV-infected cells and enhanced NK cells’ capacity to kill them. In summary, we identified a novel, glycan-based interaction that may contribute to HIV-infected cells’ ability to evade NK immunosurveillance and developed an approach to break this interaction.
Cute, cuddly and completely crushable: Plushies as avatars in video games
Authors: Reay Emma
Published: November 2021

This article examines video game avatars that are designed to resemble toys. It names this trope the ‘Blithe Child’ to capture the carefree, careless and childlike interactions this avatar invites. This article argues that the connection between the Blithe Child and traditional toys functions to express and explain non-violent game mechanics, to shape sentimental player–avatar relationships, to create cosy, snug playspaces and to encourage pro-social, creative and self-expressive playstyles. However, the Blithe Child inherits some of the more sinister dynamics latent in human–toy relationships, namely the desire to humiliate and mutilate the cute object and anxieties about what it means to be ‘real’ – to be an independent, agential subject rather than a passive, manipulated, othered object. Drawing on theories derived from cuteness studies and toy studies, this article uses a close reading approach to critique the age-based hierarchies that underpin this trope.
Playing Nature: Ecology in Video Games, Alenda Y. Chang (2019)
Authors: Henderson Brian
Published: November 2021

Review of: Playing Nature: Ecology in Video Games, Alenda Y. Chang (2019)

Minneapolis, MN: University of Minnesota Press, 294 pp.,

ISBN: 978-1-5179-0632-0, p/bk, $27.00
Surviving Mars, Haemimont Games (2018)
Authors: Johnson Heather G. S.
Published: November 2021

Review of: Surviving Mars, Haemimont Games (2018)

Stockholm: Paradox Interactive

PC download, US$29.99
Prácticas afirmativas de organización áulica en situaciones conflictivas
Authors: Gómez Ramos Daniel , Ponce Naranjo Ivonne
Published: November 2021

El presente trabajo está asociado a la colaboración de los autores en dos proyectos de investigación vinculados a la observación de la práctica docente. El enfoque del estudio es la investigación de la experiencia y la pregunta fundamental circunda las posibilidades de organización del aula en medio de situaciones conflictivas. A través de conversaciones hermenéuticas con profesores y la directora de un centro educativo se hallan como categorías de estudio: caos, desorden y afuera o exterioridad, que representan los desplazamientos del oficio docente. Los resultados reflejan una práctica afirmativa fruto de una situación límite que se presenta ante las dificultades para la aplicación de esquemas escolares y pedagógicos preconcebidos.
Luta por Dignidade e Inclusão da Pessoa com Deficiência no Ensino Público Superior
Authors: Guedes Lívia Couto
Published: November 2021

No presente artigo, a matrícula de uma estudante com deficiência visual no curso de Pedagogia Licenciatura de uma universidade pública federal do nordeste brasileiro foi mote para as reflexões filosóficas e metodológicas suscitadas em torno das ações de acessibilidade previstas para o alcance de sua efetiva inclusão social no Ensino Superior. Num percurso repleto de tensões e possibilidades, contextualizadas numa comunidade culturalmente instalada num histórico processo de exclusão e integração sociais, baseadas no modelo médico da deficiência, a noção de dignidade da pessoa humana e as consequentes lutas travadas para o vislumbre do alcance das metas inclusivas conferiu aos personagens universitários envolvidos (gestores, docentes, técnicos e discentes) a necessidade de refletirem coletivamente sobre a real localização do valor social do ser humano com deficiência, e revisitarem a relação entre os deveres institucionais e os direitos sociais e fundamentais evidenciados pela presença da aluna em tela. A partir de pesquisa exploratória, de abordagem qualitativa, gerou-se um relato de experiência que buscou expor o ponto de vista da discente e também refletir sobre o papel desempenhado pela gestão do curso de graduação, a quem restou assumir quase que solitariamente o papel de resistência na intermediação entre as demandas legítimas da aluna e o bloco de discurso e poder representados pela instituição. Entre os resultados encontrados, destacou-se a presença de barreiras atitudinais, comunicacionais e de outras ordens, tanto entre os discentes quanto nas mais altas esferas de decisão e poder institucionais. As conclusões do estudo apontam para a necessidade de um programa permanente de sensibilização e formação universitária em prol da construção da consciência inclusiva, segundo a qual a noção de valor existente no princípio da dignidade da pessoa humana possa ser pedagogicamente desvelada, independentemente de estigmas e estereótipos, em detrimento dos flagrantes de desrespeito cometidos contra a pessoa com deficiência. Por fim, pretendeu-se oferecer subsídios metodológicos para a adoção pedagógica de práticas acessíveis a partir da gestão universitária, podendo ser experimentados outros lócus de atuação pedagógica e envolver suporte a diferentes personagens em favor da inclusão social.
Aspect of Thoracoscopic Biopsy in Pleural Malignancy
Authors: Joshi Priyanka , Dhandhukiya Rajdeep , Maqsood Sheema , Bhargava Vijay
Published: November 2021

BACKGROUND Medical thoracoscopy, in the educated fingers of a pulmonologist, is a secure and powerful process for the diagnosis and treatment of many pleural diseases. If the centres for thoracoscopy are available, thoracoscopy should be carried out on those undiagnosed sufferers due to its excessive sensitivity in malignant and tuberculous pleural effusions. That is why the ultimate decade witnessed an interest in thoracoscopy as a diagnostic device for pleural diseases. In the existing study, we wanted to describe our experience with the function of thoracoscopic biopsy in patients who underwent thoracoscopy for diagnostic purposes. METHODS The study protocol and ethical approval were taken by the Institutional Review Board for human studies of B. J. Medical College, Gujarat. It was a prospective study conducted in the Department of Pulmonary Medicine, B. J. Medical College, Ahmedabad, between July 2014 and November 2016. 39 patients who underwent medical thoracoscopy for undiagnosed pleural effusions were enrolled in this study. Undiagnosed pleural effusion was defined as failure to achieve a diagnosis by initial pleural fluid analysis including pleural fluid adenosine deaminase (ADA) levels and at least three pleural fluid analyses negative for malignant cells. Diagnostic pleural fluid aspiration was done to obtain pleural fluid specimens. RESULTS In the present study with the help of thoracoscopy, 36 (92.31 %) patients were diagnosed successfully while only 3 patients remained undiagnosed. In the present study, on thoracoscopic examination 21 (53.85 %) patients had pleural nodules, 5 (12.82 %) patients had pleural thickening, 5 (12.82 %) patients had pleural plaquelike erythema. The remaining patients had other uncommon findings e.g. nonspecific pleuritis 3 (7.69 %). CONCLUSIONS Among all the patients with undiagnosed exudative pleural effusion, irrespective of smoking status which fails to respond to conventional medical management, diagnostic thoracoscopy should be considered as early as possible. The diagnostic yield of thoracoscopy for pleural pathology remains very high (92.3 %). KEYWORDS Diagnosis, Malignant Pleural Effusion, Thoracoscopy.
Physiopunk: Speculative fiction for future therapies
Authors:   Universitetet i Tromsø, Tromsø, Norway, Maric Filip , Nikolaisen Liv ,   Universitetet i Tromsø, Tromsø, Norway, Bårdsen Åse ,   Universitetet i Tromsø, Tromsø, Norway
Published: November 2021

In light of today’s deeply connected social and environmental crises, environmental and sustainability education is increasingly being integrated into public health and healthcare professional education around the world (Barna, Maric, Simons, Kumar & Blankestijn, 2020). The Norwegian ‘regulations on national guidelines for physiotherapist education’ clearly support the integration of these topics by stating that ‘in addition to individually oriented work, physiotherapists should contribute to improving public health and the sustainability of society on the group and system-levels…with competencies in interdisciplinary and goal-oriented collaborations within the health- and care-sector and other sectors…to meet societies existing and future needs’ (Forskrift om nasjonal retningslinje for fysioterapeututdanning, 2019, our translation). In a new introductory public health module for our 1st year physiotherapy students at UiT Norges Arktiske Universitet we therefore integrated education about the social and environmental problems of our time and how they interact with health at many levels to inspire students to imagine novel futures for physiotherapy and the role of healthcare professionals in the future.
A diary from the future
Authors:   Universitetet i Tromsø, Tromsø, Norway, Eikrem Stine
Published: November 2021

‘A diary from the future’ thinks through the positive social, environmental and health effects of a large-scale transition to plant-based diets. These include positive changes for food production, consumption and food security, and with that, also social justice, equity, education, poverty and the co-existence with other species. Even just the way the story thinks through and recognises these complex relationships and effects is an achievement and a novelty for physiotherapists in itself. Reaching well beyond this, however, this is also a story about how fear and darkness can turn into hope, optimism and curiosity for the future as a result of learning and thinking about these complex relationships. Finally, ‘A diary from the future’ is also a reflection on the possibilities of broadening our understanding of physiotherapy, of the need for change, resistance to it, and the creative potential that is released when these resistances are overcome.
Life under domes
Authors:   Universitetet i Tromsø, Tromsø, Norway, Molden Oda
Published: November 2021

‘Life under domes’ is set in a futuristic world after considerable further destruction has led to inhospitable, unstable weather conditions. While this has pushed human, animal and plant life into new urban settings inside domes that are safe for living, there seems to be a positive and hopefully energy contained within these domes. Technology is highly advanced and humans, robots, and artificial intelligence seem to live and work peacefully side-by-side, ensuring healthy ecosystems, fostering biodiversity, and good mental and physical health alike. Building domes and a variety of ecosystems within them becomes a healthcare intervention in itself, as it provides shelter and rehabilitative spaces for humans, plants and animals. In its exploration of new tasks for both well-established and new reasons, ‘Life under domes’ transports a sense that future societies cannot repeat what has happened ‘out there’ before. To have good health, the environmental must be protected wherever we are.
Circles
Authors:   Universitetet i Tromsø, Tromsø, Norway, Anmarkrud Sigrid Johanne
Published: November 2021

‘Circles’ takes us on a phantasy tour de force and into deep connection with the earth under our feet while, at the same time, being a prime example of creativity and imagination. In this story, future physiotherapists in the high north collect reindeer manure to support the growth of plants that can help reduce mercury pollution – a very real and longstanding problem in the Arctic. Once again, this is a story about how collaboration and curiosity can turn bad conditions to the better and open us up to new opportunities and entirely new tasks. And in the exploration of these new tasks, the digging of manure and joy of touching the earth with our hands, ‘Circles’ also reminds us that every little action has an effect on everything else and can be a meaningful contribution to healthier and more sustainable futures, no matter how distant, small or strange it might seem.
Physiopunk Vol 1: Spekulativ fiskjon for fremtidige fysioterapier
Authors:   Universitetet i Tromsø, Tromsø, Norway, Maric Filip , Nikolaisen Liv ,   Universitetet i Tromsø, Tromsø, Norway, Bårdsen Åse ,   Universitetet i Tromsø, Tromsø, Norway
Published: November 2021

Dagens sosiale og miljømessige kriser er dypt forbundet med hverandre. Miljø- og bærekraftsutdanning blir derfor stadig mer integrert i internasjonale folkehelse- og helsepersonellutdanninger (Barna, Maric, Simons, Kumar & Blankestijn, 2020). Den norske «Forskrift om nasjonal retningslinje for fysioterapeututdanning» støtter integrering av disse temaene og sier at fysioterapeuter «skal […] bidra på gruppe- og systemnivå for å fremme folkehelsen og samfunnets bærekraft […] med kompetanse i tverrfaglige og målrettede samarbeidsprosesser innenfor helse- og omsorgssektoren og i andre sektorer […] for å møte samfunnets eksisterende og fremtidige behov» (Forskrift om nasjonal retningslinje for fysioterapeututdanning, 2019).
Urban helse da og nå, en refleksjon
Authors:   Universitetet i Tromsø, Tromsø, Norway, Nygård Silje Kristin
Published: November 2021

Denne fortellingen har sitt utgangspunkt i utviklingen av bosettinger og byer gjennom historien. Med dette som bakgrunn ser forfatteren for seg en fremtid der byene, både lokalt og globalt er grønnere og mer helsefremmende.. En stadig større andel av jordens befolkning bor i byer, og med grønnere byer vil denne fremtidsvisjonen fort kunne bli mer enn fantasi. Med hjelp fra helseprofesjonene vil byplanlegging og design kunne gi oss enda flere grønne områder og bygninger. Dette gir renere luft, mer fysisk aktivitet, naturlig isolasjon i hjemmene, karbonlagring, lokal matproduksjon, økt biodiversitet og til slutt mer sosialt samvær og lykkeligere innbyggere. Ved å holde fokus på folks helse, funksjon og fysisk aktivitet, viser denne fortellingen oss at det kanskje ikke må store omveltninger til for å skape endringer. Å utvide vår profesjonelle identitet, rolle og ansvarsområde kan bidra mer enn vi har sett for oss så langt.
Verdens lunger
Authors:   Universitetet i Tromsø, Tromsø, Norway, Becker Theresa Sophie
Published: November 2021

"Verdens lunger" stiller spørsmål ved verdiene og handlingene som har ført til en verden der avskoging og karbonutslipp har skapt luftforurensning som er så alvorlig at den truer alt liv. Fortellingen beskriver et globalt skifte i verdier fra grådighet, maktmisbruk og jakt på profitt, mot ekte samarbeid og omsorg for mennesker, planter og dyr. Fortellingen minner oss om at miljøproblemer vil påvirke oss alle – både helsepersonell og pasienter – og vi må stå side om side for å snu utviklinga. Denne fortellingen gir oss ny energi gjennom økt forståelse og anerkjennelse av de sammenvevde forholdene mellom mennesker, anatomi, fysiologi og dagens sosiale og miljømessige problemer. Teksten gir en opplevelse av at å tenke og handle i større målestokk enn den individuelle kroppen gjør det mulig å håndtere kjente problemer på helt nye måter.
Ny utdannelse for fremtiden
Authors:   Universitetet i Tromsø, Tromsø, Norway, Kristiansen Camilla
Published: November 2021

Fortellingen er satt i en tid da det fortsatt er viktig å jobbe mot målene og ambisjonene som er uttrykt i FN’s bærekraftsmål. Innsikt i sammenhenger mellom samfunn, helse og miljø og behovet for langsiktig, tverrfaglig handling har ført til etableringen av et nytt bachelorstudium for helse og bærekraft. Bak denne typen utdannelse og praksis ligger en utvida forståelse av helse. Tverrfaglig utdanning og kommunikasjon har blitt den nye normalen, og gir grobunn for ny optimisme. Samtidig fører det til at vi må stille kritiske spørsmål til fysioterapifaget; Vil vi holde fast ved fysioterapifaget slik vi kjenner det nå, eller vil vi endre det? Vil vi motarbeide eller bidra til opprettelsen av nye profesjoner og helhetlige tilnærminger? Hva vil vårt bidrag til å løse de komplekse sosiale og miljømessige utfordringene være?
Deeply touching
Authors:   Auckland University of Technology, Auckland, New Zealand, Nicholls David A
Published: November 2021

In many ways, this remarkable collection of eco-fiction essays, produced by students at UiT Norges arktiske universitet, commissioned and curated by Filip Maric, Liv Johanne Nikolaisen, and Åse Bårdsen, and beautifully illustrated by Heike Jane Zimmermann, reflect a lot of our present thoughts about the social and environmental crises that can already be ‘glimpsed in the distance along existing thought pathways’ (Morton 2016, p.1). ‘This is the future’, Tim Morton tells us, ‘that is simply the present, stretched out further’.
Toekomsten met fysiotherapie
Authors:   HAN University of applied sciences, Nijmegen, Gelderland, Netherlands, van Wijchen Joost
Published: November 2021

Opeens bevind ik mij in een andere werkelijkheid, in andere werkelijkheden. Overvallen door een mengeling van bewondering en bevreemding. Bewondering voor de creativiteit van deze (aankomende) collegae. Bewondering voor de inkijk in mogelijkheden, wensen en behoeften. Maar tegelijkertijd ook bevreemding door de confrontatie met andere realiteiten met daarin een mix van bekende en onbekende elementen, in een variatie van contexten. Een geheel van indrukken, welke gedachten en emoties oproepen. De 8 verhalen en het inleidend schrijven van “Physiopunk initiatief”, laten een rijkheid zien aan mogelijkheden. Mogelijkheden niet zo zeer ten aanzien van wat ze nu zijn, maar juist naar wat kan gaan zijn, wat kan worden. Door het lezen van de verhalen merk ik dat ik mijzelf beweeg tussen verschillende plateaus. Deze plateaus hebben voor mij wel een relatie, maar geen directe hiërarchie. Ik zal hieronder de verschillende plateaus toelichten.
Physiotherapy 2.0: Necessity is the mother of innovation
Authors:   Western Norway University of Applied Sciences, Bergen, Norway, Sudmann Tobba T
Published: November 2021

The first part of the title paraphrases Web 2.0, which refers to websites that emphasize user-generated content, ease of use, participatory culture, and interoperability for end users. The eight physio sci-fi stories can be appreciated as fragments of Physiotherapy 2.0, where users are understood to be physiotherapists, co-workers, patients, citizens, or other stakeholders, who take initiative and responsibility for launching physiotherapy 2.0.
Isumaqatigingniq: Building a Transformational Science Education Model to Engage the Next Generation of Inuit and Western Scientific Investigators
Authors: Nweeia Martin T. , Peeters Pamela
Published: November 2021

Inuit Qaujimajatuqangit (IQ), “the Inuit way of knowing,” and science each approach observation of the natural and physical world from shared yet different epistemologies. Studies that integrate IQ and science demonstrate the inherent value of using observations and findings from both to understand Arctic systems. Yet holders of IQ and scientists often do not fully comprehend the practice of the other because they think and approach observation and knowledge differently. Using the concept of Isumaqatigingniq, or “thinking together,” we will form an educational program, Isumaqatigingniq-Science, Technology, Engineering and Mathematics, (I-STEM), that will highlight and integrate studies of the narwhal and the Arctic environment undertaken with contributions from IQ and science. Program outreach will target high school students from both Inuit and non-Inuit backgrounds. Understanding existing efforts that combine these knowledge frames will hopefully inspire future collaborations by these groups. Learning through I-STEM will better equip students to address scientific themes that design, optimize, and implement collaborative observation systems. Inuit and scientific research efforts are essential for a deeper understanding of the Arctic environment. Implementing an active educational program that engages high school youth to understand the value of incorporating these two ways of knowing will help foster a future educational environment of collaboration. The educational I-STEM model will bring a new Inuit perspective to formal scientific education programs and share perspectives of science and Inuit knowledge within Inuit educational programs. Isumaqatigingniq can continue growing, incorporating new perspectives on Arctic observations and knowledge.
Morphological variability and genetic diversity of Aman rice germplasm of Bangladesh cultivated in Mymensingh region
Authors: Emi Fahmida Reza , Khatun Hadisa , Yasmine Fahmina , Hasan Ahmed Khairul , Hossain Mohammad Anwar
Published: November 2021

Thirty-one Aman rice germplasm were evaluated to assess their morphological variability and genetic diversity considering ten quantitative and thirty one qualitative traits at the field experimental plot of Bangladesh Institute of Nuclear Agriculture, Mymensingh, following randomized complete block design. The germplasm showed significant differences for all the studied traits. The highest grain yield/plant was recorded in Sentu-16 whereas the lowest was found in Gaindha. The genotypic coefficient of variation (GCV) was lower than those of the corresponding phenotypic coefficient of variation (PCV) for all the traits. High PCV and GCV along with heritability, genetic advance (GA) and GA in percentage of mean were recorded for number of filled grains/panicle and number of unfilled grains/panicle. Grain yield/plant had positively significant correlation with plant height, number of total tillers/hill, number of effective tillers/hill, number of filled grains/panicle and thousand grain weight. Path co-efficient analysis suggested that grain yield/plant had positive direct effect in association with days to fifty percent flowering, number of effective tillers/hill, panicle length, number of filled grains/panicle and thousand grain weight. Principal component analysis revealed that the first three components accounted for 79.57% of cumulative variance. Cluster analyses were revealed that the studied rice germplasm organized into five clusters based on D2 values where maximum inter-cluster distance was observed between cluster II and V. Qualitative characterization by distinctness, uniformity and stability test revealed that a wide range of variation was observed among the genotypes. Therefore, this study would be useful for breeders to choose and identify the revival and preservation of beneficial genes for crop improvement.
Acknowledgments Networks in Accounting Scholarship: A Note
Authors: Andrikopoulos Andreas , Kostaris Konstantinos , Zounta Stella
Published: November 2021

We explore social networks in accounting research. Our sample spans the 1996–2015 period and includes all research articles that were published in the Accounting Review, Journal of Accounting Research, Journal of Accounting and Economics, Accounting Organizations and Society, Review of Accounting Studies, and Contemporary Accounting Research. Employing social network analysis, we delineate and discuss the structure of scientific collaboration as it appears in the acknowledgments of published research articles. We identify the most central nodes in this nexus of intellectual partnership. Furthermore, we discover that acknowledgments constitute a small-world social network, with high average clustering coefficient and small average distance within a giant component which covers the biggest part of the acknowledgment network.
Identificación de una nueva mutación en el gen humano xantina causante de la xantinuria tipo I
Authors: Collazo Abal Cristina , Romero Santos Susana , González Mao Carmen , Pazos Lago Emilio C. , Barros Angueira Francisco , Castiñeiras Ramos Daisy
Published: November 2021

Objetivos

La xantinuria es una enfermedad rara, de herencia autosómica recesiva caracterizada por la presencia de hipouricemia y elevada excreción de xantina, provocada por el déficit de xantina deshidrogenasa/oxidasa (XDH/XO, EC: 1.17.1.4/1.17.3.2) en el tipo I, o por el déficit de XDH/XO y aldehído oxidasa (AOX, EC: 1.2.3.1) en el tipo II.

Métodos

Describimos una nueva mutación puntual en homocigosis en el gen XDH en un paciente con niveles muy bajos de ácido úrico en suero y orina y xantinuria. Aunque el paciente se encontraba asintomático, se objetivaron cálculos renales en las pruebas de imagen.

Resultados

Se detectaron otros casos en su familia, y se le hicieron recomendaciones dietéticas para prevenir futuras complicaciones.

Conclusiones

La xantinuria hereditaria es una patología infradiagnosticada, que se suele descubrir accidentalmente al detectar en un análisis rutinario la presencia de hipouricemia. Es importante que la medicina de laboratorio sepa orientar a los facultativos en su diagnóstico.
The importance of the self: using online diaries in the EFL classroom
Authors: Beseghi Micòl
Published: November 2021

Learner journals, diaries, and logs have been used in a variety of learning contexts, including foreign language learning. This paper investigates how diary writing can be used in the EFL classroom to encourage students to express their identities through the language they are learning; it is also a way of supporting them in their quest for greater autonomy, with a view to exploring the interconnections between learner autonomy, learner self (L2 self), and learner emotions. More specifically, it will be shown how reflective writing – in the form of online diaries – can offer learners an important tool to explore their thoughts and emotions and reflect on their identity as learners and users of English. Moreover, diaries are a qualitative research tool for teachers and scholars, who can examine metacognitive and affective aspects of language learning. The paper reports a study conducted within a university English Language course, in which the students were encouraged to keep a reflective online diary throughout a semester. The analysis of their personal and expressive writing has shed light on their need to speak as themselves, not just as language learners, and to explore their emotions, both positive and negative. A final questionnaire has revealed that the students were generally positive about the activity, highlighting its usefulness in terms of learner autonomy, self-awareness, and self-regulation.
Thermal-strength analysis of a cross-flow heat exchanger and its design improvement
Authors: Konieczny Mariusz , Felkowski Łukasz
Published: November 2021

After a year of the heat exchanger operation in overload conditions, a number of cracks on the tube connections to the tubesheet have been observed. To explain the stress concentration and crack initiation, a finite element analysis is performed. A three-dimensional model is constructed and analyzed. To calculate more precisely the state of stress in the most loaded regions, a submodel is created. The maximum stress exceeds the allowable stress, and according to the standards, it can lead to ratcheting. To reduce stress concentration, all tubes should be shortened and corrugated tubes are installed in the high-temperature region from the side of the burner. A finite element model of the modified heat exchanger and a submodel are created. In the modified heat exchanger, ratcheting should not occur according to the applied standards. During the operation of the modified heat exchanger, there are no further problems with cracking.
Asymptotic Properties of a Supercritical Branching Process with Immigration in a Random Environment
Authors: Wang Yanqing , Liu Quansheng
Published: November 2021

This is a short survey about asymptotic properties of a supercritical branching process

(

Z
n

)

(Z_{n})

with immigration in a stationary and ergodic or independent and identically distributed random environment.
We first present basic properties of the fundamental submartingale

(

W
n

)

(W_{n})

, about the a.s. convergence, the non-degeneracy of its limit 𝑊, the convergence in

L
p

L^{p}

for

p
≥
1

p\geq 1

, and the boundedness of the harmonic moments

E
⁢

W
n

-
a

\mathbb{E}W_{n}^{-a}

,

a
>
0

a>0

.
We then present limit theorems and large deviation results on

log
⁡

Z
n

\log Z_{n}

, including the law of large numbers, large and moderate deviation principles, the central limit theorem with Berry–Esseen’s bound, and Cramér’s large deviation expansion.
Some key ideas of the proofs are also presented.
Design and Experimental Validation of Miniaturized Self-Triplexing Antenna Employing HMSIW
Authors: Althuwayb Ayman A.
Published: November 2021

The design and experimental verification of miniaturized cavity-backed self-triplexing antenna (STA) with high-isolation employing half-mode substrate integrated waveguide (HMSIW) are presented in this work. The proposed STA is constructed by using HMSIW, an Y-shaped slot and three 50Ω feed lines. Three unequal radiating patches are generated by engraving an Y-shaped slot on the top surface of the HMSIW cavity to operate at 3.7/5.0/5.8 GHz for WiMAX/WLAN applications. The proposed STA allows to realize one of the operating band independently by keeping other operating band unaltered and vice-versa. The circuit area of STA is highly miniaturized due to the use of HMSIW cavity and loading of Y-shaped slot. The isolations between three ports are greater than 31 dB. The fabricated STA provides 5.5, 5.92 and 5.93 dBi peak gains at 3.7, 5.0 and 5.8 GHz, respectively. The efficiency of the STA is greater than 92% at all the frequency bands. The constructed STA has a front-to-back ratio of more than 23 dB and a separation of more than 21 dB between co-to-cross polarization levels. Fabrication and measurement are used to validate the intended STA.
Design and microwave-assisted synthesis of a novel Mannich base and conazole derivatives and their biological assessment
Authors: Cebeci Yıldız Uygun , Karaoğlu Şengül Alpay
Published: November 2021

4-Amino-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one(1)was converted to the corresponding Schiff base(2)by treatment with salicylaldehyde. 1,2,4-Triazoles were then converted to the corresponding Mannich bases containing fluroquinolone core using a one-pot three-component procedure. Moreover, the synthesis of six compounds, which can be considered as conazole analogues, was performed starting from 1,2,4-triazole-3-one compounds via three steps by either conventional or microwave-mediated conditions. All the newly synthesized compounds were screened for their antimicrobial activities. Most exhibited good to moderate antibacterial and/or antifungal activity. The structural assignments of the new compounds were based on elemental analysis and spectral (IR,1H NMR,13C NMR, and LC-MS) data.
Zwischen Geschichtswissenschaft, Volkskunde und ‚Philologie‘. Zur Protosoziologie der mittelhochdeutschen Literatur (1895–1930)
Authors: Benz Maximilian
Published: November 2021

According to widespread prejudice, it was only about 1900 that the influence of society on literature became an important scholarly issue. On the contrary, it will be demonstrated that, since the beginnings of its literary history, the literature of the Middle Ages has been discussed within its social context. At the same time, it will be shown in this article that between 1895 and 1930 some exceptional figures, in particular, Paul Kluckhohn and Edward Schröder, though representing the intellectual atmosphere of their time, nonetheless contributed to the development of a method of correlating medieval society and literature that until today remains of more than historical interest.
‚Arbeit an den Sachen selbst‘. Zu Praxis und Programmatik der Literatursoziologie Karl Viëtors
Authors: Zelle Carsten
Published: November 2021

This article focuses on Karl Viëtor’s (1892–1951) literary-sociological oriented Baroque research and follows its development up to a generalized literary-sociological research program. Viëtor defines his stance on the sociology of literature by distancing himself from two strands of thought: on the one hand, from different versions of “Geistesgeschichte” (represented e. g. by Fritz Strich, Oskar Walzel, or Emil Ermatinger), and, on the other hand, from various materialistic positions based on the base/superstructure-model (such as those by Franz Mehring or Karl August Wittfogel). First, I will examine Viëtor’s unpublished lecture History of German Literature in the Age of Baroque (Geschichte der deutschen Literatur im Zeitalter des Barock, 1922/1923 until 1937), which is his repository for his baroque publications in the 1920 s, that also inspired in-depth research conducted by his students. Secondly, I will analyze Viëtor’s Program of a Sociology of Literature (Programm einer Literatursoziologie, 1934), a critical examination of relevant contributions by Erich Rothacker and others, both from bourgeois and Marxist backgrounds. In this text, Viëtor outlines the sociology of literature in two ways: as a sociology of literary life and as a sociology of literary works.
Literatursoziologie als Kunstsoziologie und die Rolle des Ästhetischen. Beobachtungen zur Disziplinentektonik im ersten Drittel des 20. Jahrhunderts, am Beispiel Heinz Sauermanns und René Königs
Authors: Sneis Jørgen
Published: November 2021

This paper explores the sociology of art as a subfield of disciplines other than sociology in the first few decades of the 20th century. Special attention is paid to the so-called “allgemeine Kunstwissenschaft” as a conceptional framework for the sociology of art, as described by Heinz Sauermann and René König. It is argued that notions of the artwork’s aesthetic properties, traditionally subject to philosophical aesthetics, co-determine the scope and range of sociological approaches to art. This is also the case with the sociology of literature.
Torque ripple minimization of multi-level inverter fed PMSM drive using modified MPTC
Authors: Dharmendra Kumar Poondla , Ramesh Tejavathu
Published: November 2021

This paper focuses on investigating the steady-state and dynamic performance of the permanent magnet synchronous motor (PMSM) drive using modified model predictive torque control (MPTC) method with multi-level inverters (MLIs). The MPTC method is simple and easy to implement for motor control as they don’t involve cascaded PI controllers unlike required the conventional controllers, such as field oriented control (FOC) and direct torque and flux control (DTFC). The proposed modified MPTC method eliminates the use of weighing factors and it is a fusion of model predictive current control (MPCC) and MPTC. Initially, the proposed modified MPTC fed PMSM drive is implemented using two-level inverter. It provides better steady-state and dynamic performance, but the ripple contents of torque, flux, and currents are high. In order to reduce the ripple contents and improve the performance of the PMSM drive, a modified MPTC is implemented using three-level inverter. The proposed modified MPTC fed PMSM drive using two-level and three-level inverters are simulated in MATLAB/SIMULINK environment under different operating conditions, such as no-load, loading, speed reversal, step change in speed operations. In order to show the effectiveness and feasibility of the proposed method, it is also validated with the experimental results.
“Hybrid” scientific conference: lessons learned from the digital annual meeting of the CARS international conference during the Covid-19 pandemic
Authors: Ostler Daniel , Steger Jana , Bernhard Lukas , Yu Kevin , Hartwig Regine , Feussner Hubertus , Wilhelm Dirk
Published: November 2021

Objectives

Due to the coronavirus disease 2019 (Covid-19) pandemic, all scientific conferences in the year 2020 had to be adapted in their form of presence to accommodate for safety regulations, postponed, or canceled entirely. As organizers of the annual Computer Assisted Radiology & Surgery International Conference & Exhibition (CARS)-Conference 2020, we decided to hold a “hybrid” conference, i.e., a virtual conference with partial presence to mitigate the drawbacks of a purely virtual conference. It is the purpose of this paper to describe the results and experience gained by our first hybrid conference.

Methods

Besides technical necessities like an online conferencing tool, we introduced additional personal namely the technical chairs and communication officers ensuring a smooth flow of presentations. To measure the success of the hybrid conference, we assessed various parameters during the conference (e.g., counting of adverse events, delays, and no-shows) and sent a questionnaire to participants for evaluation after the conference.

Results

We offered four types of presentation formats, whereas the majority of speakers presented their pre-produced videos including live discussions. Significant delays in sessions occurred during the morning sessions, which could be reduced during lunch breaks. The analysis of the influence of the distribution of the audience’s location/time zone toward the attendance rate showed a high relevance for the American zone and only little influence for the Asian-Pacific region. Based on the questionnaire, 60% of responders considered the hybrid approach as superior and 12% as inferior to purely virtual conferences.

Conclusions

Most scientific associations in 2020 had to struggle with a dramatic change: Regular, traditional meetings with personal communication and exchange, networking, and creation of new visions became obsolete almost instantly. As an alternative, virtual conferences became increasingly popular, and are offering additional advantages (e.g., reduction of cost for travel, lodging, and time on transit). To overcome the drawbacks of purely virtual conferences, we introduced a hybrid concept for the CARS-Congress. While certainly, those with the privilege to take part personally on-site did benefit most from the hybrid format. Facing upcoming waves of the Covid-19 Pandemic, with ongoing changes to the regulations on meetings and transit, hybrid conferences are a viable option for scientific conferences for the future.