bluuebunny/crossref_metadata_2025 huggingface dataset:
Diretriz Brasileira sobre a Saúde Cardiovascular no Climatério e na Menopausa – 2024
Authors: Oliveira Gláucia Maria Moraes de , Almeida Maria Cristina Costa de , Artucio Carolina , Macedo Larissa Neto Espíndola , Rivera Maria Alayde Mendonça , Silva-Filho Agnaldo Lopes da , Marques-Santos Celi , Fernandes Cesar Eduardo , Albuquerque Carlos Japhet da Matta , Freire Claudia Maria Vilas , Izar Maria Cristina de Oliveira , Costa Maria Elizabeth Navegantes Caetano , Castro Marildes Luiza de , Lemke Viviana de Mello Guzzo , Lucena Alexandre Jorge Gomes de , Brandão Andréa Araujo , Macedo Ariane Vieira Scarlatelli , Polanczyk Carisi Anne , Lantieri Carla Janice Baister , Nahas Eliana Petri , Alexandre Elizabeth Regina Giunco , Campana Erika Maria Gonçalves , Bragança Érika Olivier Vilela , Colombo Fernanda M. Consolim , Barbosa Imara Correia de Queiroz , Rivera Ivan Romero , Kulak Jaime , Moura Lidia Zytynski , Pompei Luciano de Mello , Baccaro Luiz Francisco , Barbosa Marcia M. , Rodrigues Marcio Alexandre Hipolito , Albernaz Marco Aurelio , Paniagua Maria , Paiva Maria Sanali Moura de Oliveira , Sanchez-Zambrano Martha B. , Campos Milena dos Santos Barros , Acevedo Monica , Ramirez Mónica Susana , Souza Olga Ferreira de , Medeiros Orlando Otávio de , Carvalho Regina Coeli Marques de , Bonassi Rogerio Machado , Silva Sheyla Cristina Tonheiro Ferro da , Rodrigues Thais de Carvalho Vieira , Avila Walkiria Samuel , Costa-Paiva Lúcia , Wender Maria Celeste Osorio
Published: May 2024

As mulheres, que representam cerca de metade da população mundial segundo estimativas de janeiro de 2024, podem sofrer com sinais e sintomas da menopausa durante pelo menos um terço de suas vidas, quando apresentam maiores risco e morbimortalidade cardiovasculares.
Os efeitos da terapia hormonal da menopausa (THM) na progressão de eventos de aterosclerose e doença cardiovascular (DCV) variam de acordo com a idade em que a THM é iniciada e o tempo desde a menopausa até esse início. Efeitos benéficos nos resultados de DCV e na mortalidade por todas as causas ocorreram quando a THM foi iniciada antes dos 60 anos de idade ou nos 10 anos que se seguiram à menopausa. A decisão sobre o início, a dose, o regime e a duração da THM deve ser tomada individualmente após discussão sobre benefícios e riscos com cada paciente.
Para a prevenção primária de condições crônicas na pós-menopausa, não se recomendam o uso combinado de estrogênio e progestagênio em mulheres assintomáticas nem o uso de estrogênio sozinho em mulheres histerectomizadas.
Neoplasias hormônio-dependentes contraindicam a THM. Para tratamento da síndrome geniturinária da menopausa, pode-se utilizar terapia estrogênica por via vaginal em pacientes com fatores de risco cardiovascular conhecidos ou DCV estabelecida.
Para mulheres com contraindicação à THM ou que a recusam, terapias não hormonais com eficácia comprovada (antidepressivos, gabapentina e fezolinetante) podem melhorar os sintomas vasomotores.
Os implantes hormonais manipulados, ou hormônios “bioidênticos” “manipulados”, e a ‘modulação hormonal’ não são recomendados pela falta de evidência científica de sua eficácia e segurança.
POLÍTICAS PÚBLICAS Y EDUCACIÓN INCLUSIVA EN COMUNIDADES RURALES DEL PERÚ
Authors: Vilca Jesús Chuchon
Published: May 2024

La educación inclusiva representa un derecho de todo ciudadano y es deber del Estado subsidiar una educación sin restricciones y de calidad con el fin de favorecer el logro de una vida plena para todas las personas, atendiendo principalmente a aquellos con necesidades especiales para su aprendizaje. El objetivo de este trabajo fue analizar las políticas públicas de educación inclusiva para las comunidades rurales del Perú. El estudio se sustenta en una revisión sistemática de la bibliografía disponible en las bases de datos Scopus, SciELO y WoS. Fueron analizados 30 artículos cuyo período de publicación se encuentra entre 2018 y 2023. Los resultados muestran que la educación inclusiva sigue siendo un reto para el estado peruano, evidenciándose como factor principal todo tipo de discriminación; no se ha entendido bien el contenido más universal de la educación inclusiva; los docentes no están suficientemente formados para asumir la experiencia de la enseñanza con estudiantes con necesidades especiales y la educación inclusiva e intercultural en las zonas andinas es poco atendida por los Estados. Finalmente, se concluye que la familia andina aún no es involucrada plenamente en la política de inclusión.
Rotating Dielectric Barrier Discharge Plasma Source for Effective Bacterial Decontamination of Bioaerosols
Authors: Isabelli Pasquale , De Baerdemaeker Klaas , Devlieghere Frank , Gherardi Matteo , Laurita Romolo
Published: May 2024

The airborne transmission of pathogens such as bacteria and viruses via aerosols is one of the most insidious ways of spreading diseases, such as COVID-19, hospital-acquired infections (HAIs), and, in the food industry, contamination of processed foods with food pathogens. Due to their small size, the nuclei of such aerosol droplets can remain suspended in the air for a long time and travel long distances. It is thus of high importance to identify increasingly effective solutions in terms of microbial decontamination of air to be used as a stand-alone application or in synergy with traditional techniques (e.g., filters and UV lamps). In this study, a DBD architecture, rotating dielectric barrier discharge, (RDBD) was devised. Its efficacy as a plasma source was tested inside a chamber containing bioaerosols contaminated with Staphylococcus epidermidis. The results showed that RDBD achieves bacterial inactivation levels greater than 3.6 Log 10 CFU, comparable to those achieved with a commercial device operating at comparable ozone concentrations. Moreover, an observable distinction lies in the reduced average discharge power exhibited by RDBD compared to the power output of the commercial device. Additionally, it is noteworthy that the air flow rate elaborated by RDBD surpasses that of the commercial device by a factor of 3.5. Furthermore, the empirical demonstration established a strong correlation between mean discharge power and resulting ozone concentration, underscoring their pivotal roles in bacterial inactivation. Conversely, the voltage range examined in this investigation does not manifest any discernible effect on the inactivation of microorganisms, given comparable power levels and ozone concentrations. Consequently, these last parameters are critical in scaling a plasma source for air decontamination.
A DODECAGON SLOTTED CIRCULAR TWO-ELEMENT SUB-6 GHZ FLEXIBLE ANTENNA FOR WEARABLE APPLICATIONS USING MODAL ANALYSIS
Authors: John Deepthi Mariam , Vincent Shweta , Pathan Sameena , Ali Tanweer
Published: May 2024

The sub-6 GHz 5G band has opened doors for a seamless and high-data-rate communication system connecting multiple devices. Multiple-input/multiple-output (MIMO) antennas are the backbone of such reliable communication systems with enhanced channel capacity. In this paper, a flexible two-element antenna is proposed for wearable applications. The dodecagon-slotted modified circular patch antenna with a defective ground structure gives isolation of 18 dB over the bandwidth. The antenna exhibits a gain of 3.38 dBi at the operating frequency of 4.8 GHz. A characteristic mode analysis was performed to investigate the resonance behavior of the antenna. Furthermore, specific absorption rate analysis was performed and found to be 0.790/0.314 W/kg for 1/10 g of tissue at 4.8 GHz. The MIMO diversity metrics exhibited an envelope correlation coefficient < 0.001, total active reflection coefficient < -10 dB, diversity gain ≈ 10, mean effective gain < -3 dB, channel capacity loss < 0.40 bps/Hz, and multiplexing efficiency < 0 over the operating frequency band.
Impacto del metabolismo socio-urbano en el Estado de México, México 2010-2020
Authors: Montoya Dainiz , Cadena-Vargas Edel-Gilberto
Published: May 2024

El Estado de México es una entidad mexicana que enfrenta problemas socioambientales: destrucción de recursos forestales, contaminación del agua y del aire, y mala calidad en los servicios básicos. Este trabajo analiza su metabolismo socio-urbano entre 2010 y 2020, considerándolo como una máquina termodinámica. Con el uso del Análisis de Flujo de Materiales y Energía (MFAE) se obtuvieron indicadores de consumo y emisiones de electricidad, combustible, agua y aspectos sociales (escolaridad, seguridad social, población económicamente activa y el PBT). Se calcularon Índices Metabólicos (IM) para indicar su consumo por municipio. Los resultados mostraron incrementos en consumos de combustible (275%); agua (130%); disminución en el consumo de electricidad (-65,7%), debido a costos; hacinamiento y robo; lo que indica una incapacidad gubernamental en la provisión de servicios. En la cuestión social, la calidad educativa desciende a pesar de la disminución de la población analfabeta. El acceso a la seguridad social ascendió (27%) en 2020, pero las entidades públicas están en quiebra y el 47,9% de la población es pobre. Los IM mostraron que los municipios más consumidores son los del Valle de Toluca y los conurbados a la Ciudad de México. A pesar de la alineación de los planes de urbanismo a los Objetivos de Desarrollo Sostenible (ODS), estos no se alcanzan debido a metodologías que no contemplan las leyes termodinámicas, la complejidad socioambiental y, por tanto, una sustentabilidad a largo plazo.
El uso de las TIC para el desarrollo de prácticas inclusivas en el aula desde la perspectiva de los futuros docentes
Authors: Pérez María José
Published: May 2024

La presente investigación se centra en conocer, desde la perspectiva de los futuros docentes, estudiantes de un Centro Universitario adscrito a la Universidad de Murcia, el grado de uso de las TIC para el desarrollo de prácticas inclusivas en las aulas ordinarias.
Así, se identificaron las necesidades existentes en este ámbito por medio del cuestionario de recogida de información creado por Pegalajar (2015) y dividido en cuatro dimensiones: las implicaciones didácticas de las TIC para la educación inclusiva, el desarrollo profesional docente hacia las TIC, la actitud docente hacia la inclusión a través de la TIC y la práctica docente inclusiva a través de las TIC.
El mismo ha sido utilizado en el Trabajo de Fin de Máster (TFM) que da lugar a esta publicación para encuestar a 34 estudiantes de 4º, de los grados de Educación Infantil y Primaria. Los resultados obtenidos han dado lugar a unas conclusiones muy positivas, ya que han considerado más que adecuada la implementación de las TIC como recurso inclusivo en los centros ordinarios. Específicamente, ha resultado más imprescindible la formación docente y la actitud de estos profesionales hacia estas tecnologías, frente a la repercusión de las mismas en el proceso de enseñanza y el desarrollo de una educación inclusiva a través de ellas.
La importancia de formar en inclusión digital durante la formación inicial docente: una revisión narrativa de la literatura
Authors: Sanz-Benito Iván , Queralt-Romero Marta
Published: May 2024

En la actualidad, la educación se encuentra en una encrucijada transformadora donde la omnipresencia de la tecnología digital (TD) redefine la manera en que vivimos, trabajamos y, especialmente, aprendemos. Las TD han revolucionado la educación, motivo por el cual, garantizar que el profesorado esté debidamente preparado para esta transformación se ha vuelto una necesidad ineludible. Para comprender plenamente esta situación, es esencial examinar una serie de perspectivas, conceptos y marcos nacionales e internacionales sobre la Competencia Digital Docente (CDD) y la inclusión digital. Mediante una revisión narrativa de la literatura, este estudio analiza cómo se aborda la inclusión digital desde una triple perspectiva: la formación inicial docente (guías docentes), la función docente (currículos educativos), así como en los marcos de referencia de la CDD y la inclusión digital (COMDID, DigCompEdu y UNESCO). Los resultados que se desprenden del estudio revelan que, dentro del conjunto de las guías docentes de las universidades catalanas evaluadas (n=10), el grado de educación primaria destaca como el que presta mayor atención a la inclusión digital, seguido del de infantil. Asimismo, se observa que las asignaturas de carácter optativo son las que más abordan esta temática, seguidas de cerca por las asignaturas de formación básica, y, en tercer lugar, las obligatorias. En lo que respecta a la función docente, se constata que los currículos de educación infantil y educación primaria en Cataluña incorporan de manera transversal la inclusión digital en la mayoría de los ejes y áreas curriculares.
Necesidades y perspectivas de la integración de la inteligencia artificial generativa en el contexto educativo español
Authors: Saz-Pérez Fabio , Pizà-Mir Bartolomé
Published: May 2024

Este trabajo aborda la metodología Delphi mediante un panel de expertos para la detección de necesidades y perspectivas sobre la integración de herramientas de inteligencia artificial generativa. Los resultados obtenidos tras la última ronda indican un alto acuerdo entre los diferentes evaluadores (W de Kendalll =,751). Las principales preocupaciones y necesidades detectadas son: la necesidad de replantear los métodos de enseñanza-aprendizaje y evaluación, la necesidad de obtener recursos formativos debido a su escasez, así como la preocupación por el fraude y la necesidad de formación del profesorado. Al mismo tiempo, se pasó el mismo cuestionario a profesores y profesores en formación, mostrando percepciones diferentes a las de los expertos.
PANEL DATA APPROACH IN SOLID FUEL ANALYSIS: THE CASE OF TURKIYE
Authors: YALÇINKAYA Senai , KORKMAZ Murat
Published: May 2024

Introduction: It is a fact that developing countries of the world and Turkiye have an important place in energy consumption. This study is very important to understand the developments in the solid fuel sector in the period 2016-2023 and the dynamics underlying these developments. This study focuses on the solid fuel sector in Turkiye for the period 2016-2023. The data used in the study consists of data obtained using Panel data analysis method and analysed with E-Views 8.0 program. Aim: To investigate the relationship between solid fuel factors and their interactions. Scope: Within the scope of the study, statistical analysis methods such as unit root tests, Granger causality analysis, cointegration analysis, covariance analysis and regression analysis were used and analysed. Results: It was found that solid fuel variables do not contain unit root. In other words, they were found to be stationary after the analysis and statistical evaluation. While a negative relationship was found between imports and production, a positive relationship was found between exports and production. While no negative relationship was found between deliveries and production, a causality relationship was found between exports and production. While a causal relationship was found between production and delivery, a causal relationship was found between imports and exports and production. A causal relationship was also found between exports and deliveries. Conclusion: In line with the findings and results obtained after this study, the relationships and interactions between the variables in the solid fuel sector in Turkiye have been revealed. These findings can provide important guidance to stakeholders and policy makers in the sector and form the basis of future strategic decisions.
Protocol for Facially Guided Digital Diagnosis in Orthodontics and Interdisciplinary Dentistry v2
Authors: HG Kelley Rupert , Ferrando Cascales Álvaro , Ferrando Cascales Raúl
Published: May 2024

As the digital age of dentistry continues to flourish, it has never been more important to have protocols to guide dentists through the planning and performance of treatments using the latest technology and software. This is especially true in the field of orthodontics, where the use of technology has revolutionised treatment outcomes. During the first stages of this protocol, extensive records are collected which are then used throughout the treatment. These records are superimposed to provide a 3D 'virtual patient'. After that, a shift occurs from two dimensions to three dimensions, and movement of the maxillary teeth begins. Then, the mandibular teeth are moved, and the case is completed. The final step is to check the results and ensure that the outcome matches what was planned before the commencement of treatment. This protocol aims to guide orthodontists in the treatment of their patients no matter the type of treatment that is planned, whether orthodontic, restorative or surgical. At any stage of the treatment, the orthodontist can refer back to the protocol to stay on the path towards a successful outcome for the patient.
Quantitative analyses of the ultrastructural features of dopaminergic axon terminals v2
Authors: M Doig Natalie , J Magill Peter
Published: May 2024

The release of dopamine from axons is critical for normative brain function and behaviour. Impaired or otherwise inappropriate dopamine release often correlates with changes in the ultrastructure of dopamine neuron axons that can assessed with electron microscopy. Here, we provide two protocols that can be used serially to, first, help the user process animal brain tissue for electron microscopy and, secondly, help the user undertake quantitative analyses of the ultrastructural features of dopaminergic axon terminals in the brain. Protocol #1 describes how to prepare brain tissue, carry out pre-embedding immunohistochemistry for tyrosine hydroxylase as a marker of dopaminergic axons, and then make tissue sections ready for electron microscope. Protocol #2 details how to examine and image ultrathin sections of tissue using a transmission electron microscope and then how to analyse the digital images.
Midbrain organoid differentiation in spinner flasks. v1
Authors: Parfitt gustavo.parfitt
Published: May 2024

Midbrain differentiation protocol using spinner flasks.
Artificial Cerebrospinal Fluid VIII (ACSF.VIII) v2
Authors: Institute for Brain Science Allen
Published: May 2024

This protocol describes how to make Artificial Cerebrospinal Fluid VIII (ACSF.VIII). ACSF.VIII is used for multiple applications including incubation of fresh human brain slices prior to electrophysiological recording. Note: Research reported in this publication was supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number U19MH114830. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
O efeito da pandemia por covid-19 no atendimento da síndrome coronariana aguda: coorte retrospectiva
Authors: Lopes Alexandra Nogueira Mello , Santarém Michelle Dornelles , Beghetto Mariur Gomes
Published: May 2024

Objetivo: avaliar a contribuição da pandemia por COVID-19 sobre os tempos de atendimento e desfechos clínicos de admissões relacionadas à Síndrome Coronariana Aguda. Método: Coorte retrospectiva. Os dados foram analisados pelo SPSS®, versão 20.0, empregados testes paramétricos e não paramétricos para comparar os grupos. Aplicado o Modelo linear generalizada para análise multivariada. Resultados: Incluídos 434 pacientes no período pré-pandemia e 430 durante a pandemia. Delta-t foi maior no período durante a pandemia(p=0,003). Não encontramos diferença nos tempos de atendimento e mortalidade. Admissão no período da pandemia(RR1,56; IC95%:1,30-1,87) e ter diagnóstico de cardiopatia isquêmica prévio(RR1,82; IC95%:1,50-2,20) foram associados ao aumento do Delta-t. Conclusão: Não houve diferença no número de pacientes que acessou a emergência por Síndrome Coronariana Aguda nos períodos analisados. Apesar do Delta-t ter sido maior durante a pandemia, não foram observados piores desfechos clínicos.
Ladányi János
Authors: Kovács Éva , Vajda Róza
Published: May 2024

Ladányi János 1971-ben végzett közgazdászként a Marx Károly Közgazdaságtudományi Egyetemen. Mindig is nagyon érdekelte a szociológia, azon belül is leginkább a különböző jellegű társadalmi egyenlőtlenségek. Miután lediplomázott Ferge Zsuzsa ajánlására a Szakszervezetek Országos Tanácsánál kapott munkát, ahol az életszínvonal-politika kutatócsoport tagja volt. Szelényi Iván hívására részt vett a Márkus István-féle nagyszabású falufelvételben, és figyelme már ekkor a községekben élő munkások felé fordult. Későbbi kutatásait ugyancsak falun élő munkásokról folytatta, aminek következményeképpen hamar találkozott a romakérdéssel. Településszociológiai érdeklődése a társadalmi rétegződés területi egyenlőtlenségekben való kifejeződése és a szegregáció témája felé terelte. Az elszegényedett, gettósodó falvak, a cigánytelepek létrejöttének és fennmaradásának okait, majd a falvak újrakörzetesítésének kérdését kezdte vizsgálni. A társadalmi egyenlőtlenségek reprodukciójának kutatása során jutott el a telepekhez és a telepi munkássághoz is. Részben az adódó lehetőségek, részben kutatótársa, Csanádi Gábor érdeklődése folytán vágott bele az iskolakutatásba, ahol megint csak a rétegződés szempontja, a gyermekek iskolák és osztályok közötti szelekciójának okai kötötték le. Az 1970-es évek második felében Újpesten, a kisegítő iskolákban végzett vizsgálatban Gerő Zsuzsa pszichológussal gyermekek rajzait is elemezték. Ladányi kutatói egyedisége abból is ered, hogy vizsgálatai mellett a segítő programok fejlesztésében is elhivatott volt. A kutatómunkához civil aktivizmus is kapcsolódott az 1989-ben kezdődő csenyétei vizsgálatban, amelyet Szelényivel, Liskó Ilonával és Horváth Aladárral együtt végeztek úgy, hogy leköltöztek a településre és részt vettek annak életében. Miután a fejlesztőprogramok rendre kudarcot vallottak, Ladányi írásaiban alaposan elemezte ennek okait és tárta fel a kettős szerepvállalásból fakadó módszertani dilemmákat. A töredékben maradt interjú Ladányinak a 2000-es évek első évtizedéig tartó munkásságát öleli fel. 2010 után sem tágított a társadalmi egyenlőtlenségek témájától, a kirekesztettség területi kivetülésének kérdéseitől. Utolsó időszakában gyermekkora helyszínéről, Újpestről, a városrész történetéről, lakóiról, valamint saját családjáról, fiaital éveiről írt személyes hangvételű, szociográfiai ihletésű köteteket, melyek közül az utolsó posztumusz jelent meg.
Miért nem vesznek részt a politikailag aktív fiatalok a pártokban?
Authors: Sebestyén Annamária
Published: May 2024

A tanulmány politikailag aktív egyetemi hallgatók körében végzett fókuszcsoportos vizsgálat tükrében a pártpolitikai részvétel ellenösztönzőinek feltárására és konceptualizálására tesz kísérletet. A téma különös relevanciával bír hazánkban, ahol – szemben a nyugat-európai demokráciákkal – a párttagság csökkenését és idősödését nem kíséri sem a civil szerveződések és a társadalmi mozgalmak felemelkedése és előretörése, sem pedig a politikai pártok marginalizálódása a politikai rendszerben. Az eredmények arra utalnak, hogy nemcsak a pártpolitikai mozgósítás hiánya, hanem maga a toborzás aktusa is fontos visszatartó erőt képez, ennél azonban nagyobb súllyal vannak jelen a politikailag aktív hazai egyetemisták pártoktól való elzárkózásában olyan társadalmi és politikai jellegű tényezők, amelyek részben a történelmi múltra vezethetők vissza, részben pedig a jelenlegi társadalmi és politikai körülményekből fakadnak. Mindemellett a tanulmány arra is rávilágít, hogy a pártokban részt vevő kortársak negatív megítélése is hozzájárul a fiatalok távolmaradásához.
AI-Optimized Customer Segmentation for Targeted Cryptocurrency Marketing
Authors: Khair Md Abul
Published: May 2024

This study examines how AI-optimized consumer segmentation may enhance well-focused Bitcoin marketing campaigns. The primary goals are to investigate the theoretical underpinnings, conduct empirical evaluations, and offer valuable recommendations for cryptocurrency marketers. Methodologically, a thorough literature research is carried out, and then actual data from the real world is used for empirical analysis. Important discoveries show that AI-driven segmentation promotes user engagement, increases marketing efficacy, and supports long-term growth in the Bitcoin ecosystem. However, restrictions like algorithmic bias and data privacy issues demand policy changes. To solve these issues, it is advised to implement ethical standards, industry collaboration, educational initiatives, and regulatory guidelines. This study demonstrates how AI-optimized segmentation may revolutionize targeted cryptocurrency marketing by promoting user loyalty, meaningful interaction, and sustainable growth.
A multicentre phase III study comparing efficacy and safety of novel extended-release versus conventional formulation of dydrogesterone in Indian patients with endometriosis
Authors: Sasikala T. , Kushwaha Shikha , Agarwal Mukta , Jain Vandana , Bawa Deepti , Narayan Suchitra , Daultani Pavankumar , Jaiswal Ashok , Chinda Monika , Singh Anit
Published: May 2024

Background: The aim of the study was to compare the efficacy and safety of novel once-daily extended-release (ER) dydrogesterone 20 mg versus conventional twice-daily dydrogesterone 10 mg in Indian patients with endometriosis.
Methods: A phase III prospective, randomized, double-blind, single-dummy, two-arm, active-controlled, parallel, multicenter study was performed in six gynecology centers across India. The patients of 18 to 45 years of age with a confirmed diagnosis of endometriosis on ultrasonography (USG) and having endometriosis-associated pelvic pain score (EAPP) of at least 30 mm on a 100 mm visual analog scale (VAS) were randomly assigned to a 1:1 ratio to either once-daily dydrogesterone ER 20 mg or twice-daily dydrogesterone 10 mg arms for a treatment period of 90 days. The primary outcome was a change from baseline in EAPP score at the end of the treatment.
Results: A total of 228 patients with a mean age of 31.8±6.9 years were enrolled in the study. At day 90, both the treatment arms showed a significant reduction (p<0.05) in EAPP score from baseline (i.e. -34.2±15.3 mm and -33.1±14.8 mm in once daily dydrogesterone ER and twice daily dydrogesterone 10 mg, respectively), with no significant difference between the two arms (p=0.53). With both formulations, patients experienced a significant reduction in the size of endometrioma, serum vascular endothelial growth factors (VEGF) levels, use of rescue analgesics, and significant improvement in the health-related quality-of-life parameters. A favorable safety profile of dydrogesterone was confirmed, and no significant safety concerns were reported during the study.
Conclusions: Once daily dydrogesterone ER 20 mg and twice daily dydrogesterone 10 mg demonstrated a significant and similar reduction in EAPP and all other secondary parameters along with marked improvements in parameters related to quality of life.
Tecnologias sociais para inclusão social em comunidades tradicionais na Amazônia
Authors: Chaves Maria do Perpétuo Socorro Rodrigues , Almeida Antônia Lúcia Silva de , Chaves João Marcelo Rodrigues
Published: May 2024

A sociedade contemporânea e a comunidade acadêmica compartilham o consenso de que a educação é essencial para o desenvolvimento socioeconômico de uma nação. Sob esta premissa, este trabalho relata a experiência de pesquisa, extensão e estágio curricular do Grupo de Pesquisas Interação na formação de profissionais, para atuarem junto às comunidades ribeirinhas da região Amazônica, baseados no Método Interação (Pesquisa-Ação). Na execução da pesquisa, são adotados um conjunto integrado de técnicas e instrumentais para coleta de dados, dentre eles: pesquisa bibliográfica e documental, aplicação de formulários semiestruturados, entrevistas com informantes-chave, dinâmicas de abordagem grupal e individual junto aos grupos doméstico-familiares para fomentar a participação dos comunitários locais e instituições. Os resultados visam instrumentalizar as organizações comunitárias e os grupos doméstico-familiares na produção de inovações e tecnologias sociais que sejam ambientalmente sustentáveis, e no fornecimento de subsídios qualificados para as instituições regionais de políticas públicas para o desenvolvimento de ações afirmativas de cidadania para a inclusão social.
A importância da educação básica no Brasil, no contexto da quarta revolução industrial
Authors: Fernandes Gilberto Lourenço
Published: May 2024

A partir da análise dos principais fatores que impulsionam a 4ª Revolução Industrial e de seu atual estágio de evolução e, considerando seus possíveis impactos sociais e econômicos, particularmente quanto à eliminação de postos de trabalho tradicionais e a criação de novas ocupações, esse artigo examina a importância da Educação Básica com foco na necessária adaptação de metodologias de ensino, da qualificação profissional exigida para a entrada no novo mercado de trabalho, como formas de enfrentamento aos desafios e aproveitamento das novas oportunidades que se apresentam.
Delimitação e mitigação de lacunas selecionadas da aprendizagem e do ensino
Authors: Alvares Lillian Maria Araujo de Rezende , Barbosa dos Santos Marcello José
Published: May 2024

Explora os complexos desafios, problemas persistentes e contratempos inesperados, contidos no ecossistema educacional e que inevitavelmente levam às lacunas de ensino e aprendizagem. Analisa toda a extensão de sua cadeia de ocorrências, passando por saber o que causa tais fragilidades e que medidas podem ser tomadas para evitar que aconteçam. Apresenta sucintamente as teorias de aprendizagem, seguido das contribuições dos grandes pensadores da educação, com destaque para David Paul Ausubel (1918-2008), com sua aprendizagem significativa e alguns modelos de ensino e aprendizagem, com destaque para o modelo A systems framework of the teaching/learning process de William G. Huitt (1995). De outro lado, traz os constructos do ensino, ressaltando que o processo se refere ao fluxo de conhecimento do professor ao aluno, ou em amplo entendimento, do ensinante ao aprendente, do educador ao educando. Traz John Dewey (1859-1952), o educador que defendeu a necessidade de um ensino contextualizado e orientado aos interesses individuais dos alunos. O trabalho finaliza considerando os principais propulsores da educação do século 21 e encerra propondo algumas iniciativas de mitigação dos problemas.
La importancia de la educación básica en Brasil en el contexto de la cuarta revolución industrial
Authors: Fernandes Gilberto
Published: May 2024

Partiendo del análisis de los principales factores que impulsan la 4ª Revolución Industrial y de su actual estado de evolución, y considerando sus posibles impactos sociales y económicos, especialmente en lo que se refiere a la eliminación de empleos tradicionales y a la creación de nuevas ocupaciones, este artículo examina la importancia de la educación básica, con especial atención a la necesaria adaptación de las metodologías de enseñanza y a las cualificaciones profesionales requeridas para acceder al nuevo mercado laboral, como formas de afrontar los retos y aprovechar las nuevas oportunidades que se presentan.
The impact of technology on education
Authors: Foina Paulo Rogério
Published: May 2024

Technology has been impacting the entire society, not only by means of its benefi ts in comfort and increased productivity, but also, and mainly, by changing human relationships and the way power is exercised. We are in a time of transition where practices, concepts and values from past centuries coexist with behaviors, values and structures from the 21st century. This coexistence, not always peaceful, is the biggest challenge that political actors in society (including teachers and education operators) face in their daily lives.
Delimitation and Mitigation of Selected Gaps in Learning and Teaching
Authors: Alvares Lillian Maria Araujo de Rezende , Santos Marcello José Barbosa dos
Published: May 2024

This paper explores the complex challenges, persistent problems, and unexpected setbacks within the  educational ecosystem that inevitably lead to teaching and learning gaps. It analyzes the entire extent of their  occurrence chain, examining what causes these weaknesses and what measures can be taken to prevent  them. The paper briefl y presents learning theories, followed by contributions from major educational thinkers,  notably David Paul Ausubel (1918-2008) with his concept of meaningful learning, and some teaching and  learning models, with emphasis on William G. Huitt’s (1995) “A systems framework of the teaching/learning  process.” On the other hand, it discusses the constructs of teaching, highlighting that the process refers to  the fl ow of knowledge from teacher to student, or broadly, from the educator to the learner. It features John  Dewey (1859-1952), the educator who advocated for contextualized teaching tailored to individual student  interests. The paper concludes by considering the main drivers of 21st-century education and proposes  some initiatives to mitigate the identifi ed problems.
Ranula– A case report and literature review
Authors: Divya VC  , Krishnakumar Surya
Published: May 2024

Ranula, a salivary gland disorder, manifests as a cystic swelling on the floor of the mouth and can arise from various etiologies such as trauma, obstruction, or inflammation. This article explores the diversity of treatment modalities proposed for ranula, including incision and drainage, marsupialization, and sublingual gland removal. The recurrence of ranula is discussed in relation to treatment types, with reported rates varying significantly. This article discusses a case study of intraoral swelling in a 19-year-old male patient, emphasizing the importance of understanding and managing ranula in clinical practice.
vigencia del alterum non laedere en el ordenamiento jurídico ecuatoriano, ¿un principio general o un deber jurídico?
Authors: Flores Larrea Ana Paula , Izquierdo Izquierdo Iván Andrés , Guzmán Burbano Felipe Nicolás
Published: May 2024

El alterum non laedere, neminem laedere o también conocido como el deber general de no dañar, históricamente ha generado discusiones en cuanto a su existencia, reconocimiento y alcance. La principal crítica que se le hace es sobre su incidencia en la seguridad jurídica, ya que su reconocimiento absoluto implicaría que todo y cualquier daño es indemnizable. Por otro lado, si no se lo reconociese, se estaría dejando en indefensión a las víctimas de daños injustos no tipificados. Por ello, primero, se buscará entender al alterum non laedere a través de su concepto, desarrollo histórico y sus principales críticas. Segundo, se analizará la naturaleza jurídica del deber de no dañar para entender su alcance. Por último, se evaluará su reconocimiento a partir de la normativa y jurisprudencia ecuatoriana, en contraste con el sistema de España y Argentina. Así, se pretende dar luces para la aplicación del alterum non laedere, de tal manera que se alcance su eficacia máxima.
Three new additions to the earthworm (Clitellata: Megadrili) fauna of Kerala state from the Western Ghats biodiversity hotspot, south-western India
Authors: Narayanan Sasankan Prasanth , Paliwal Rahul , Thomas Basil , Thomas Ambattu Paili , Julka Jatinder Mohan
Published: May 2024

In India, studies on above-ground biodiversity have received more attention than those on below-ground biodiversity. With this view, systematic surveys for earthworms were carried out in the Western Ghats mountain range of Kerala state in southwestern corner of Peninsular India. This research resulted in three new records for the state, viz. Drawida nandiensis Stephenson, 1924, D. nepalensis Michaelsen, 1907 and Celeriella bursata Jamieson, 1977. Among these, D. nandiensis and D. nepalensis, are recorded for the first time from the Western Ghats biodiversity hotspot. Previously D. nandiensis and C. bursata were known only from their respective type localities. With the addition of three species the total number of earthworm taxa reported from Kerala state has raised to 128 and now the Western Ghats mountain ranges has 271 species of earthworms.
A Magyar Nyelvőr és a Magyar Nyelv 1905 és 1925 közötti történetéhez
Authors: Kiss Jenő
Published: May 2024

A tanulmányban a szerző korabeli dokumentumok alapján szól hozzá a címben jelzett témakörhöz. Megállapítja, hogy sem a Magyar Tudományos Akadémia, sem a Magyar Nyelvőr nem játszott szerepet a Magyar Nyelv 1905-ös megindításában. A Magyar Nyelv című folyóiratot a Magyar Nyelvtudományi Társaság alapította saját folyóirataként. A Magyar Tudományos Akadémia csak 1925-től segítette megjelentetését.
Dynamics of Performance Appraisal among Staff in the Ministry Of Education and Training in Lesotho
Authors: Makhetha Isaiah M.
Published: May 2024

The objective of this study was to determine whether employees are appraised in an objective manner in the Ministry of Education and Training in Lesotho and also to establish whether performance appraisal brings about intended results in this ministry. This investigation adapted a mixed-methods approach. The population comprised 100 employees of the Ministry of Education and Training. A sample of 50 officers was selected from the population using proportionate stratified random sampling. Data were collected through a use of a questionnaire. The reliability of this instrument was ascertained through employing the split halves which consequently yielded the reliability coefficient of 0.82. Chi-square analysis revealed that employees are appraised in an objective manner in the Ministry of Education and Training in Lesotho.  On the other hand, chi-square analysis showed that performance appraisal does not bring about intended results in this ministry. On the basis of these results, it was concluded that performance appraisal is conducted in an objective manner in the Ministry of Education and Training in Lesotho and also that performance appraisal does not bring about intended results in this Ministry.
Can The Zambian Insurance Industry Use Internal Hire Versus External Hire As A Strategic Tool?
Authors: Keith Mumba , Abubaker Qutieshat
Published: May 2024

This study aimed to assess the efficacy of internal and external hiring practices as tools for strategic human resource management in the Zambian Insurance industry. The investigation analyzed the strengths and weaknesses of both internal and external hiring strategies, with a specific focus on their impact on organizational performance and employee development. Through an extensive examination of existing literature, interviews with industry professionals, and a survey of senior executives responsible for recruitment and selection processes in the Zambian Insurance sector, the study gathered data from a sample of both large and small insurance companies operating in different regions of Zambia. This ensured that the entire industry was represented. The study provided valuable insights into the strategic considerations and outcomes of internal and external hiring in this specific context, enhancing our understanding of effective human resource management practices in the Zambian Insurance industry and offering recommendations for improving talent acquisition strategies. The study also looked at the possibility of turning the human resource function in the surveyed industry from a 'day-to-day' issue to a more strategic aspect of the business through a comprehensive hiring plan and the use of internal recruitment with employee retaining strategies. In conclusion, the research findings suggest that the Zambian insurance sector has the capability to utilize both internal and external candidates as a strategic approach. The decision to choose between internal and external hiring is influenced by various factors, including financial considerations, the immediate need to fill a vacant position, the desire to bring in fresh expertise, and the compatibility with the company's culture. Internal hiring offers several advantages for the Zambian insurance industry, such as cost savings, reduced recruitment time, and the ability to foster employee growth and loyalty within the organization. Conversely, external hiring brings in new perspectives, skills, and experiences that may not be readily available internally.
基于量子化学的有机朗肯循环工质筛选策略研究
Authors: 王义  , 杨嘉雯  , 夏力  , 孙晓岩  , 项曙光  , 王丽丽
Published: May 2024

工质筛选是研究有机朗肯循环发电系统的关键内容之一。由于工质的种类多、组分结构复杂，增大了工质筛选难度。本文从工质热力学物性角度入手，开展工质筛选策略研究，提出以对比理想气体热容判定因子为依据，定量判断工质的干湿特性。当判断因子>1时为干工质，当判断因子<1时为湿工质，23种工质的计算数据和文献数据的对比结果表明，该判断因子的计算结果具有可靠性。提炼出“三步法”初步筛选策略用于有机朗肯循环的工质筛选，该策略包含工质基础物性分析、干湿特性的研究、量子化学分析，该筛选策略从微观和宏观角度解释了有机朗肯循环系统工质筛选的机理，为有机朗肯循环工质的构效关系研究奠定基础。
AÇÕES INSTITUCIONAIS PARA REDUÇÃO DA EVASÃO NA UTFPR:
Authors: Santos Cidmar Ortiz dos , Bondarik Roberto , Pilatti Luiz Alberto
Published: May 2024

O presente estudo tem como objetivo avaliar a eficácia das medidas voltadas para a redução da evasão nos cursos superiores ofertados na Universidade Tecnológica Federal do Paraná (UTFPR), durante e depois da implantação do Programa de Apoio a Planos de Reestruturação e Expansão das Universidades Federais (Reuni), para o alcance dos resultados pactuados. Trata-se de uma pesquisa de campo com abordagem qualitativa do problema. O procedimento técnico adotado foi o da pesquisa sintética de caso único com um nível de análise. O corpus de pesquisa foi composto por documentos, questionário e entrevistas. A análise das entrevistas ocorreu com análise de discurso e do questionário com estatística descritiva. Constatou-se que ações, mesmo aquém do pactuado, continuam sendo adotadas para a redução da evasão, mas as taxas permaneceram distantes do pactuado. Conclui-se que apenas com condições efetivas para a permanência dos estudantes ocorrerá uma diminuição significativa da evasão.
Produção textual na formação docente em Ciências: possíveis contribuições do ciberativismo de mulheres cientistas em contexto adverso
Authors: Sousa Francisco Raule de , Santos Adriana Cavalcanti dos
Published: May 2024

A discussão levantada neste artigo objetiva identificar as principais demandas da agenda das mulheres participantes de um evento online no canal Rede Brasileira de Mulheres Cientistas – RBMC. A partir das discussões apresentadas, serão elencadas possibilidades de reflexões sobre tópicos temáticos orientadores para o ensino de produção textual na formação inicial de docentes visando a construção de um currículo de Ciências focado no compromisso social. Por meio da análise qualitativa de natureza interpretativa, tomamos como dados a materialidade discursiva em um vídeo postado no YouTube, no canal da RBMC, sob a abordagem analítica da Análise Textual Discursiva (ATD). As categorias organizadas em iniciais, intermediárias e finais indicaram, respectivamente: organização retórica do evento, aspectos das identidades das mulheres nas apresentações pessoais e abrangência das temáticas apresentadas tanto no que se refere aos projetos em curso quanto aos desafios destacados pelas participantes das cinco regiões brasileiras. Como resultado, o metatexto aponta para discussões possíveis, no âmbito da produção textual, as seguintes questões:  busca por equidade no que tange às relações de gênero, utilização do ciberespaço como recurso potente de mobilização social e de produção de saberes no espaço acadêmico, além de reflexões sobre linguagem e ensino de Ciências.
Textual production in the teacher training in science: possible contributions of women scientists cyberactivism in an adverse context
ABSTRACT
The discussion raised in this paper aims to identify the main demands on the agenda of women participants in an online event on the Brazilian Network of Women Scientists channel – RBMC (acronym in Portuguese). Based on the discussions presented, possibilities for reflections on thematic topics guiding for the initial teacher training in textual production is going to list, with a focus on the construction of a science curriculum centered on social compromise. By means of the qualitative analysis of an interpretative nature, we take as data the discursive materiality in a video posted on YouTube, on the RBMC channel, under the analytical approach of Discourse Textual Analysis (DTA). The categories organized in initial, intermediate, and final categories indicated, respectively: rhetorical organization of the event, aspects of women's identities in personal presentations, and the comprehensiveness of the themes presented, both in terms of ongoing projects and the challenges highlighted by participants from the five Brazilian regions. As a result, the metatext aims at possible discussions in the area of textual production, including the following issues: pursuit for equity regarding gender relations, use of cyberspace as a powerful resource for social mobilization and knowledge production in the academic space, in addition to reflections on language and science teaching.
Keywords: Writing. Science. Gender. Curriculum.
Jill of All Trades: Multidisciplinary Origin Stories in Creation of the R.E.D.D. Centre for Menstrual Health
Authors: Foteva Vladimira , Wellham Michelle , William Kimberely , Qiao Yixue
Published: May 2024

With one quarter of our global populous being of menstrual maturity, it must be questioned why menstruation and menstrual products continue to remain the subject of prejudice and taboo. Such multidisciplinary problems require multidisciplinary solutions-thus the REDD Centre was formed, utilizing resources from four key areas in the healthcare, biomedical and fine arts fields. This report outlines areas of menstrual health research in the respective disciplines, which will form the basis for inter-collaborative programs to raise the status of menstruators.
The Playable City: Refeshioning Spaces within Urban Social Design
Authors: Hight Craig , Minichiello Mario , Egglestone Paul , O’Callaghan Simone , Drummond Jon , Irvine Clare , Cassin Andrea
Published: May 2024

Play is an essential part of life, a vital part of urban design, and in the case of Newcastle a possible panacea for late night inner-city anti-social behaviour. This presentation introduces a pilot urban design project focused on the design of sets of interactive ‘henges’ across three central Newcastle city locations. Developed through collaborative design with the city council and local SMEs, these henges feature site-specific digital and sensor-based forms of interaction. They represent an innovative approach to shifting patterns of night-time anti-social behaviour within specific locations by reimagining these sites as arenas for individual and social play. The henge sites aim to prompt discussion with city communities over the value of play within urban design and engage citizens in future smart city initiatives. This presentation discusses the challenges of deploying interactive technologies within urban social design, argues for the need to prioritise forms of play within smart city planning, and outlines a collaborative research design involving multiple urban stakeholders.