bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioactive compounds enrichment in rabbit doe’s diet pre-and during pregnancy improves productive and reproductive performance and cost-effectiveness under hot climates
Authors: El-Speiy Mohamed E. , Zeitoun Moustafa M. , El-Sawy Mohamed A. , Sadaka Tarek A. , Abou-Shehema Bahaa M. , Abdella Mohamed M. , Shahba Hossam A. , Habib Mahmoud R.
Published: October 2024

This study aimed to investigate the effect of diet supplementation with a symbiotic (SY), bee pollen (BP), honey bee (HB), date palm pollen (DPP) and their mixture (MIX) on female rabbit productive and reproductive performances under desert hot climates. Seventy-two Californian does of 5 months age and average body weight of 3250 ± 78.2 g were randomly allotted into six groups, each of 12 does. All does orally receive 3 ml distilled water for 10 days before mating and 28 days during pregnancy. Treatments were repeated for four consecutive parities. The first group served as control (C) given distilled water only, however the second, third, fourth and fifth groups were supplemented with 3 ml distilled water containing 0.2 ml SY, 200 mg DPP, 200 mg BP, 0.2 ml HB/doe per day, respectively. While, the sixth group does were given all previous ingredients (MIX). Sexual receptivity rate, fertility rate, kindling rate, and newborn traits were recorded. Also, maternal feed intake, feed conversion ratio, and digestibility coefficients of nutrients were recorded. Does in all groups were artificially inseminated with 0.5 ml of fresh heterospermic semen of 15 fertile bucks extended in Tris at 806–1006 sperm/ml. Treatment increased maternal body weight and daily gain with highest values (P < 0.05) in BP, SY, and MIX does. All treatments enhanced feed intake and feed conversion ratio (FCR) compared with control. Number services per conception decreased (P < 0.01), while litter size and weight and survival at birth and weaning increased (P < 0.01) in treated than control does. Treated does produced more milk than control. Digestibility coefficients of all nutrients were improved (P < 0.01) in treated does. In conclusion, supporting rabbit does pre- and during pregnancy with diets supplemented with a mixture of honey bee, date palm pollen, bee pollen, and synbiotic improves the productive and reproductive performances of rabbit does and their offspring.
Optimized biosynthesis of lytic enzymes by special Trichoderma citrinoviride
Authors: Piegza Michał , Łaba Wojciech
Published: October 2024

The use of Trichoderma filamentous fungi in the wide concept of biocontrol is still a highly relevant topic. The multifaceted nature of their impact on phytopathogenic microorganisms results from the species diversity and complexity of their antagonistic action. The presented research aimed to determine optimal cultivation conditions of two T. citrinoviride strains for the biosynthesis of major enzymes especially those involved in the biocontrol process. Culture conditions were optimized using a three-factor Box-Behnken design to maximize the yield of chitinase and lichenase. The following independent variables were included in the model: incubation temperature, initial pH, and supplementation with fungal biomass. As a result of statistical optimization, unprecedented activities of extracellular lytic enzyme were achieved. For the B1 and B3 strains, the optimal pH was 3.5 or 7.5, respectively, in the determination of chitinase biosynthesis. It was similar for the biosynthesis of β-1.3 and β-1.4 glucanases, but at higher cultivation temperature. The exception was the B3 strain, for which the optimal pH in glucanase biosynthesis was 5.5. The most stimulating culture temperature in the process of chitinase biosynthesis and β-1.3 and β-1.4 glucanases was above 25 °C. In that, the levels of enzyme biosynthesis and corresponding composition culture environment were confirmed to be strain-dependent.
Versatile Conductive Ink Formulation for Enhanced Electrochemical Performance in Flexible Printed Micro-supercapacitors Using SnO2/rGO Nanocomposites
Authors: Rathod Akshata , Saquib Mohammad , Lakshmikanth M. , Nayak Ramakrishna , Selvakumar M.
Published: October 2024

The rise of flexible and wearable electronics has spurred advancements in printed, flexible micro-supercapacitors for energy storage. This study presents the fabrication of flexible micro-supercapacitors using a novel nanocomposite of tin dioxide grown on layered reduced graphene oxide through one-pot in situ synthesis. The conductive functional ink, formulated by mixing the nanocomposite, is effectively utilized in screen-printing technology. The resulting micro-supercapacitors, particularly the SG-1 variant, demonstrate impressive electrochemical performance. The nanocomposites show exceptional versatility across various electrolytes, including alkaline, acidic, and quasi-gel electrolytes with a polyvinyl alcohol matrix infused with potassium hydroxide. An in-depth comparison of their efficacy in these electrolytes highlights the most suitable configurations for optimal performance. At a scan rate of 5 mV s−1, SG-1 achieves areal capacitances of 148.7 mF cm−2 and 87.7 mF cm−2 in the 1 M KOH and polyvinyl alcohol infused with 1 M KOH quasi-gel electrolyte. Additionally, SG-1 in the gel electrolyte demonstrates remarkable energy density of 11.7 mWh cm−2 at power density of 490 mW cm−2. Notably, the fabricated micro-supercapacitors exhibit excellent capacitive retention of 89.5% even after undergoing 5000 cycles of charge–discharge, underscoring their robustness and long-term stability for practical applications in flexible and wearable electronics.
Prescribed burning alters soil microbial community structure by changing soil physicochemical properties in temperate forests of northern China
Authors: Hu Tongxin , Han Yu , Köster Kajar , Wang Jianyu , Hu Haiqing , Dou Xu , Sun Long , Ding Yiyang
Published: October 2024

Prescribed burning is commonly used to maintain forest ecosystem functions and reduce the risk of future wildfires. Although many studies have investigated the response of microbial community to wildfires in forest ecosystems, the effects of prescribed burnings on soil microbial community structure are less studied. It is also unclear that how post-fire soil physiochemical properties changes affected soil microbial communities. Here, we studied the impacts of prescribed burning on soil microbiome in three typical temperate forests of northern China by collecting soil physicochemical and high-throughput sequencing for 16S rRNA and 18S rRNA was applied to analyze the diversity and community composition of soil microbes (bacteria and fungi). Compared with pre-fire condition, prescribed burning significantly decreased Chao1 index and altered soil bacterial communities (P < 0.05), whereas it had no significant effect on fungal diversity and community structure of the (P > 0.05). Planctomycetes and Actinobacteria made the greatest contributions to the bacterial community dissimilarity between the pre-fire and post-fire conditions. The main variables influencing the post-fire soil microbial community structure are soil pH, available phosphorus, total nitrogen, and the ratio of soil total carbon to soil total nitrogen, which could account for 73.5% of the variation in the microbial community structure in these stands. Our findings demonstrated a great discrepancy in the responses of bacteria and fungi to prescribed burning. Prescribed burning altered the soil microbial structure by modifying the physicochemical properties. Our results pointed that it is essential to evaluate the impact of prescribed burnings on forest ecosystem functions. These findings provide an important baseline for assessing post-fire microbial recovery in the region and offer critical guidance for restoration efforts.
Influencer marketing effectiveness: A meta-analytic review
Authors: Pan Meizhi , Blut Markus , Ghiassaleh Arezou , Lee Zach W. Y.
Published: October 2024

Influencer marketing significantly impacts consumer behavior and decision-making. However, identifying the drivers of influencer marketing effectiveness and conditions that enhance their impact remains challenging. This meta-analysis, which synthesizes 1,531 effect sizes from 251 papers, assesses influencer marketing effectiveness by examining its antecedents, mediators, and moderators. Building on the persuasion knowledge model to develop and test a framework, we identify post, follower, and influencer characteristics as key antecedents impacting both non-transactional (i.e., attitude, behavioral engagement, and purchase intention) and transactional (i.e., purchase behavior and sales) marketing outcomes. For non-transactional outcomes, follower characteristics (social identity) have the strongest effects on consumer attitudes and behavioral engagement, while post characteristics (informational value and hedonic value) exert stronger effects on purchase intention. For transactional outcomes, influencer characteristics (influencer communication) have the strongest effects on purchase behavior. These antecedents also affect marketing outcomes indirectly through persuasion knowledge and source credibility. Moderation results indicate that direct and indirect effects of antecedents depend on social media types (i.e., nature of connection and usage) and product types (i.e., information availability and status-signaling capability). These results consolidate and advance the literature and offer insights into enhancing the effectiveness of influencer marketing.
Multi-layer Active Biopolymer System as a Perspective for Improving the Quality and Scope of Applying Semi-rigid Biodegradable Packaging
Authors: Nowak Nikola , Tkaczewska Joanna , Cholewa-Wójcik Agnieszka , Grzebieniarz Wiktoria , Piasna-Słupecka Ewelina , Drozdowska Mariola , Jamróz Ewelina
Published: October 2024

In this study, the possibility of modifying a multi-layer biopolymer active system to reduce permeability to gases of a biodegradable material with potential application in food technology was analysed. A four-layer biopolymer film was used, wherein the initial two layers comprised furcellaran, whilst the subsequent two layers were a mixture of chitosan and gelatin. The film was modified with active ingredients, including silver nanoparticles (AgNPs), montmorillonite, a curcumin-capsaicin mixture and gelatin hydrolysate. The film formed an integrated, semi-rigid packaging system together with the tray, which was developed from tea brewing waste and biopolymers. Application properties were assessed by analysing mechanical parameters, key to the assessment of their quality, proving that the active ingredients significantly improved the strength properties. There was an almost twofold increase in modulus of elasticity values compared to the control film. The permeability against oxygen was also assessed as the main performance characteristic of the packaging and was only 13.64 ± 3.92 [cm3/m2 × 24 h]. The impact of the applied material innovation in packaging on the freshness of food products was also evaluated by analysing the microbiological purity of stored Salmo Salar fillet. The active, biodegradable packaging extended the shelf-life of salmon by 6 days compared to the low-density polyethylene (LDPE) film. Toxicity analysis has shown that the used active ingredients are safe for the environment and consumers.
Circle-circle intersection. A universal method for solving typical surveying problems
Authors: Gargula Tadeusz
Published: October 2024

The research problem of the article is to devise a universal mathematical procedure for calculating point coordinates from typical planar surveying measurements. The proposed solution involves calculating the intersection points of two circles with radii equal to the measured distances (the distance-distance intersection problem). The author demonstrates a straightforward method for reducing every typical surveying problem to the distance-distance intersection form. The procedure also verifies the accuracy of the calculated coordinates. The derived equations were tested numerically using practical examples. The devised procedure will be integrated into an exhaustive numerical algorithm for diverse surveying problems regardless of the geometric approach during measurements.
PDFO: a cross-platform package for Powell’s derivative-free optimization solvers
Authors: Ragonneau Tom M. , Zhang Zaikun
Published: October 2024

The late Professor M. J. D. Powell devised five trust-region methods for derivative-free optimization, namely COBYLA, UOBYQA, NEWUOA, BOBYQA, and LINCOA. He carefully implemented them into publicly available solvers, renowned for their robustness and efficiency. However, the solvers were implemented in Fortran 77 and hence may not be easily accessible to some users. We introduce the PDFO package, which provides user-friendly Python and MATLAB interfaces to Powell’s code. With PDFO, users of such languages can call Powell’s Fortran solvers easily without dealing with the Fortran code. Moreover, PDFO includes bug fixes and improvements, which are particularly important for handling problems that suffer from ill-conditioning or failures of function evaluations. In addition to the PDFO package, we provide an overview of Powell’s methods, sketching them from a uniform perspective, summarizing their main features, and highlighting the similarities and interconnections among them. We also present experiments on PDFO to demonstrate its stability under noise, tolerance of failures in function evaluations, and potential to solve certain hyperparameter optimization problems.
Effect of zearalenone in sugar beet products on zootechnical and reproductive performance and lesions of sows and piglets
Authors: Grümpel-Schlüter A. , Kersten S. , Kluess J. , Lühken S. , Saltzmann J. , Schubbert A. , Büngener-Schröder S. , Dänicke S.
Published: October 2024

Following the use of sugar beet pulp that was retrospectively found to be predominantly contaminated with zearalenone (ZEN) in diets of reproducing sows largely exceeding the EU-guidance value for critical ZEN concentration of 0.25 mg/kg, farmers did not report any changes in the reproductive performance of sows. Thus, the aim of the study was to verify this guidance value in a dose–response setup by using sugar beet pulp as a ZEN source hitherto not considered a risky feedstuff additionally characterized by comparatively low levels of deoxynivalenol. A total of 90 sows was equally allocated to one of the three feed groups during experimental lactation 1 and up to 40 days after insemination: CON with a minimal ZEN concentration, ZEN1 with a target concentration of 250 µg ZEN/kg feed, and ZEN2 with a target concentration of 500 µg ZEN/kg feed. Thereafter, all sows received the same feed without ZEN for the rest of gestation, and the following lactation for testing of putative carry-over effects resulting from previous ZEN exposure. Exposure of sows to ZEN with blood serum as an indicator was linearly related to dietary ZEN concentrations. Reproductive and zootechnical performances of sows were only affected by ZEN exposure at weaning weight. Clinical-chemical parameters indicated no clear effect of ZEN exposure. An influence of ZEN on the occurrence of tail and ear injuries (not necrosis) in piglets and lesions on the mammary complexes in sows is possible. The influence of a ZEN concentration above the EU guidance value on the study farm can therefore not be neglected.
A novel approach to assessing food insecurity for small geographic areas using household living budgets
Authors: Montalvo Cesar , Lancaster Vicki , Salvo Joseph J. , Shipp Stephanie
Published: October 2024

The USDA Economic Research Service has monitored food insecurity at national and state levels since 1995 using the Current Population Survey Food Security Supplement. But if a food insecurity measure is to inform action and target interventions, it must be constructed for smaller geographic levels that consider geographic price differences. This article constructs a novel measure of food insecurity using an alternative approach based on financial needs of households, known as the household living budget (HLB). The HLB is defined as the income required to satisfy a household's essential needs, enabling it to maintain a modest yet sufficient standard of living while covering federal and state income taxes. The HLB is constructed at the census tract level and incorporates three key determinants of food insecurity: household size and composition, household income, and food costs. We demonstrate how the HLB along with publicly available data can be used to construct a food insecurity measure using a residual income approach to assess if households are able to afford paying for food expenditures and assess the qualification thresholds of the Supplemental Nutrition Assistance Program (SNAP). Food insecurity estimates are obtained for households in Washington, D.C. and benchmarked to regional results provided by a survey sponsored by the Capital Area Foodbank.
Decoupling anthropogenic, climatic, and tectonic factors in the hydrology of playa-lakes in a semi-arid, tectonically active region (betic orogen, southern Spain)
Authors: Rodríguez-Rodríguez M. , Jiménez-Bonilla A. , Díaz-Azpiroz M. , Gázquez F.
Published: October 2024

Here, we explore the dynamic interplay of climate, tectonic forces and human impacts, that have shaped the current hydrology of the 27 main endorheic continental playa-lakes in southern Spain, most of them protected as Natural Reserves. This research offers a thorough examination of the hydro-geomorphic, geochemical, and tectonic characteristics that influenced the development of these wetlands. We introduce and apply several hydro-morphological indices that effectively characterize the hydrological functioning of these wetlands. Importantly, the examination of the geological setting and analysis of recent tectonics has been found to be effective in reconstructing the evolution of some of the major playa-lakes, including Fuente de Piedra playa-lake and El Gosque playa-lake. Lastly, the analysis of satellite information using the online tool water occurrence change intensity (WOCI) of Surface Water Explorer in the studied playa-lakes was found to be inconsistent in the long-term analysis. Enhanced attention is required to refine the WOCI tool, thereby ensuring a more precise depiction of wetland dynamics in the Mediterranean. Fine-tuning will better represent complex behaviors, thus improving its utility for monitoring and managing wetlands in the region.
GVAF: generalized, flexible filtering software for annotated variant files
Authors: Kim Sora , Jung Sungwon
Published: October 2024

Background

In the rapidly advancing field of genomics, many tools have been developed to interpret genetic variants using next-generation sequencing (NGS) data. However, these tools often produce annotated variant files in different formats, which require specific software or programming skills to filter and analyze.

Objective

To provide a filtering tool that can be used with diverse variant annotation tools without requiring specific software or programming skills.

Methods

We developed Germline Variant Annotation and Filtering (GVAF), a command-line software tool that can handle annotated variant files in any table-shaped format. GVAF offers powerful filtering operations without the need for additional software or programming expertise.

Results

Built on the Java framework and bash scripts, it provides extensive features, including flexible filtering rules, recognition of genotype-related fields from variant call format (VCF) files, and customizable result generation. GVAF also integrates easily into existing data analysis pipelines. Compared to other tools, GVAF offers a broader range of functionalities, making it more flexible and intuitive for managing annotated variant files.

Conclusion

This GVAF software and online manual is publicly available at https://www.sysbiolab.org/gvaf for academic users and is designed to streamline the variant interpretation process, aiding researchers in producing meaningful results.
Speech-mediated manipulation of da Vinci surgical system for continuous surgical flow
Authors: Kim Young Gyun , Shim Jae Woo , Gimm Geunwu , Kang Seongjoon , Rhee Wounsuk , Lee Jong Hyeon , Kim Byeong Soo , Yoon Dan , Kim Myungjoon , Cho Minwoo , Kim Sungwan
Published: October 2024

With the advent of robot-assisted surgery, user-friendly technologies have been applied to the da Vinci surgical system (dVSS), and their efficacy has been validated in worldwide surgical fields. However, further improvements are required to the traditional manipulation methods, which cannot control an endoscope and surgical instruments simultaneously. This study proposes a speech recognition control interface (SRCI) for controlling the endoscope via speech commands while manipulating surgical instruments to replace the traditional method. The usability-focused comparisons of the newly proposed SRCI-based and the traditional manipulation method were conducted based on ISO 9241-11. 20 surgeons and 18 novices evaluated both manipulation methods through the line tracking task (LTT) and sea spike pod task (SSPT). After the tasks, they responded to the globally reliable questionnaires: after-scenario questionnaire (ASQ), system usability scale (SUS), and NASA task load index (TLX). The completion times in the LTT and SSPT using the proposed method were 44.72% and 26.59% respectively less than the traditional method, which shows statistically significant differences (p < 0.001). The overall results of ASQ, SUS, and NASA TLX were positive for the proposed method, especially substantial reductions in the workloads such as physical demands and efforts (p < 0.05). The proposed speech-mediated method can be a candidate suitable for the simultaneous manipulation of an endoscope and surgical instruments in dVSS-used robotic surgery. Therefore, it can replace the traditional method when controlling the endoscope while manipulating the surgical instruments, which contributes to enabling the continuous surgical flow in operations consequentially.
Ricci flow of Kaehlerian slant submanifolds in complex space forms and its applications
Authors: Alqahtani Lamia Saeed , Ali Akram
Published: October 2024

The normalized Ricci flow converges to a constant curvature metric for a connected Kaehlerian slant submanifold in a complex space form if the squared norm of the second fundamental form satisfies certain upper bounds. These bounds include the constant sectional curvature, the slant angle, and the squared norm of the mean curvature vector. Additionally, we demonstrate that the submanifold is diffeomorphic to the sphere $$\mathbb {S}^{n_1}$$

S

n
1

under some restriction on the mean curvature. We claim that some of our previous results are rare cases.
Random balancing-like sequences
Authors: Patra Asim , Panda Gopal Krishna
Published: October 2024

A balancing-like sequence is a binary recurrence sequence which generalizes the balancing sequence and the sequence of nonnegative integers. This sequence, under certain assumptions, may be used to describe the growth of fortune of a person engaged in some business or profession. Since, in any business or profession, the growth is influenced by many uncertainties, it is more natural to induce some sort of randomness in the balancing-like sequences. If, in a balancing-like sequence, the growth rate is assumed to be a random variable, the resulting sequence will be a stochastic process and the sequence of expectations, in many cases, cannot be described as a binary recurrence sequence. In some cases, the growth rate of expectations increases without limit while, in some cases, it remains finite.
On the transcendance of quasi-periodic Rosen continued fractions
Authors: Besbes Yosra , Hbaib Mohamed , Jellali Manel
Published: October 2024

In this paper, we consider the two Hecke groups $$G_{4}$$

G
4

and $$G_{6}$$

G
6

and we use the Schmidt Subspace Theorem to establish the transcendence of some quasi-periodic Rosen continued fractions in order to get the exact analogues of the results established with the regular continued fractions.
Novel results from quadratically nonlinear elastic wave models using Murnaghan’s potential
Authors: Hameed Hamza , Zaman F. D. , Ahmad Shahbaz , Ali Hassan
Published: October 2024

In this article, we study one, two and three-dimensional nonlinear elastic wave equations using quadratically nonlinear Murnaghan potential. We employ two effective methods for obtaining approximate series solutions the Adomian decomposition and the variational iteration method. These methods have the advantage of not requiring any physical parametric assumptions in the problem. Finally, these methods can generate expansion solutions for linear and nonlinear differential equations without perturbation, linearization, or discretization. The results obtained using the adopted methods along various initial and boundary conditions are in excellent agreement with the numerical results on MATLAB, which show the reliability of our methods to these problems. We came to the conclusion that our methods are accurate and simple to use.
Predictors of non-adherence to an early in-hospital rehabilitation program after surgery for hip fracture in a co-managed orthogeriatric unit
Authors: Presta Roberto , Brunetti Enrico , Quaranta Valeria , Raspo Silvio , Cena Paola , Carignano Giulia , Bonetto Martina , Busso Chiara , Isaia Gianluca , Marabotto Marco , Massazza Giuseppe , Bo Mario
Published: October 2024

Background

Hip fracture is a common event in older adults, leading to an increased risk of mortality, disability, and higher healthcare costs. Early in-hospital rehabilitation after surgery within orthogeriatric units may improve outcomes with limited incident complications even in the oldest old. We aimed to determine the prevalence and predictors of non-adherence to early rehabilitation in the orthogeriatric unit of an Italian tertiary hospital and its impact on outcomes and setting at discharge.

Methods

Retrospective observational single-centered cohort study. Patients aged ≥ 65 years admitted to the orthogeriatric unit for hip fracture who underwent surgery between April 2019 and October 2020 were considered eligible if able to walk autonomously or with assistance and independent in at least 2 Basic Activities of Daily Living. Along with sociodemographic and geriatric variables, characteristics of surgery and rehabilitation, in-hospital complications and functional outcomes at discharge were collected. The primary outcome was non-adherence to the early in-hospital rehabilitation program.

Results

Among 283 older patients (mean age 82.7 years, 28.6% male), non-compliance with physical therapy was assessed in 49 cases (17.3%), characterized by worse pre-fracture clinical, cognitive, and functional status and showing worse outcomes in terms of mobilization at discharge. After multivariable analysis, non-adherence was independently associated with the onset of delirium (OR 5.26, 95%CI 2.46–11.26; p < 0.001) or infections after surgery (OR 3.26, 95%CI 1.54–6.89; p < 0.001) and a systolic blood pressure at admission < 120 mmHg (OR 4.52, 95%CI 1.96–10.43, p < 0.001).

Conclusions

Pre-fracture poor cognitive and functional status, along with lower systolic blood pressure, seem to make some patients more vulnerable to in-hospital complications (mainly delirium and infections) and negatively affect the adherence to physical therapy and, by consequence, clinical outcomes of rehabilitation.
Radioligand therapy in the therapeutic strategy for patients with gastro-entero-pancreatic neuroendocrine tumors: a consensus statement from the Italian Association for Neuroendocrine Tumors (Itanet), Italian Association of Nuclear Medicine (AIMN), Italian Society of Endocrinology (SIE), Italian Association of Medical Oncology (AIOM).
Authors: Panzuto Francesco , Albertelli Manuela , De Rimini Maria Luisa , Rizzo Francesca Maria , Grana Chiara Maria , Cives Mauro , Faggiano Antongiulio , Versari Annibale , Tafuto Salvatore , Fazio Nicola , Colao Annamaria , Scalorbi Federica , Ferone Diego , Cinieri Saverio , Maccauro Marco
Published: October 2024

Purpose

This paper outlines the consensus of the Italian Association for Neuroendocrine Tumors(Itanet), the Italian Association of Nuclear Medicine (AIMN), the Italian Society of Endocrinology (SIE), and the Italian Association of Medical Oncology (AIOM) on treating neuroendocrine neoplasms (NENs)with radioligand therapy (RLT).

Methods

A list of 10 questions regarding using RLT ingastroenteropancreatic neuroendocrine tumors (GEP-NETs) was addressed after a careful review of theavailable literature. compiling information from the MEDLINE database, augmented with expert opinionsand recommendations, aligns with the latest scientific research and the author’s extensive knowledge.The recommendations are evaluated using the GRADE system, showcasing the level of evidence andthe strength of the recommendations.

Results and Conclusions

Specifically, this paper focuses on thesubcategories of well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) thatexpress somatostatin receptors and are considered suitable for RLT, according to internationalguidelines.
Nutritional aspects in neuroendocrine neoplasms. bridging the gap between dietary interventions and cancer care strategies: a scoping review
Authors: Massironi Sara , Panzuto Francesco , Zilli Alessandra , Rinzivillo Maria , Ciliberto Ambra , Romano Elena , Danese Silvio , Laviano Alessandro
Published: October 2024

Purpose

Neuroendocrine neoplasms (NENs) represent heterogeneous tumors arising from neuroendocrine cells in different organs. Despite growing interest in the nutritional aspects of NEN management, research in this area is limited. Aim of this review is to summarize the current state of knowledge, highlight research gaps, and underscore the significance of nutrition in the comprehensive care of NEN patients.

Methods

We conducted an extensive bibliographic search focusing on studies (including retrospective and prospective studies, systematic reviews, case series, and guidelines) exploring the relationship between nutritional assessments, dietary interventions, micronutrient deficiencies, and their impact on NEN outcomes.

Results

Significant gaps exist in current research, particularly in understanding the specific nutritional needs of NEN patients and how tailored nutritional interventions can improve clinical outcomes. Evidence suggests that a high-fat Western diet may promote the growth of NEN, while a Mediterranean diet may help lower insulin levels and strengthen the immune system, potentially preventing tumor development. The ketogenic diet and intermittent fasting may also have positive impacts. Addressing common micronutrient deficiencies, such as vitamin D and niacin, is crucial to mitigate disease progression. There’s a crucial need for future studies to include a comprehensive nutritional assessment incorporating patient-reported outcomes, to fully capture the impact of nutritional strategies.

Conclusion

Nutritional management, an important but under-researched facet of NEN treatment, significantly improves patients’ quality of life and survival. Integrating nutrition into personalized cancer care is essential, highlighting the role of nutritional strategies in optimizing patient outcomes.
Electrochemical characterization of TiO2 nanotubes formed on Ti6Al4V manufactured by PBF-EB or forging
Authors: Vásquez F. A. , Aguirre Ocampo Robinson , Bedoya Nicolás , Zuleta Gil Alejandro A. , Botero Carlos , Gómez Maryory , Castaño Juan G. , Tamayo José A.
Published: October 2024

This study introduces the anisotropy effect of Ti6Al4V substrate obtained by electron beam melting (PBF-EB) on the anodizing process, revealing its capacity to induce anisotropic TiO2 nanotubes. Highly organized TiO2 nanotubes are formed on Ti6Al4V substrates produced through PBF-EB or forging, with the PBF-EB cross-orientation displaying superior nanotube growth due to enhanced catalytic activity. Morphological and electrochemical characterizations underscore the significant influence of substrate orientation and anodizing voltage on nanotube growth and corrosion resistance. PBF-EB-cross orientation at 30 V exhibits a thicker and more homogeneous nanotube layer, resulting in improved film resistance and substantially lower corrosion rates compared to forged substrates. The electrochemically calculated nanotube film thickness aligns with microscopic analyses, emphasizing the importance of a homogenous and resistive nanotube coating for effective corrosion control.
Regimes of Self-Presentation and Digital Street Credibility: How Urban Youth Negotiate Online and Offline Visibility
Authors: Balleys Claire , Tadorian Marc , Colombo Annamaria
Published: October 2024

Drawing on a study of how young people in Switzerland appropriate urban public space, this article explores what we term “regimes of self-presentation” among youth in both online and offline spaces. We address issues of privacy and power that help shape such regimes by applying an expanded notion of street credibility that encompasses digital practices. Our concept of “digital street credibility” recognizes how, in today’s world, any social or cultural practices engaged in by youth have two potential types of audiences. One is physically present, consisting of other users of urban public space. The second audience is media-based, consisting of people with access to live or prerecorded digital content captured on smartphones and shared on social networks. This situation has forced young people to develop new and specific social conventions governing self-presentation. The article highlights the complex and perilous nature of visibility management. Where privacy and power relations are concerned, a very thin line separates behavior that enhances an individual’s social status from actions considered “embarrassing” or “cringe.” Our results show how, in the streets as well as online, acceptable forms of visibility are determined on the basis of digital street credibility. These findings suggest a need to reconsider young people’s understanding of privacy, as it relates to their leisure activities in urban and digital spaces.
Analysis of policy changes for Yangtze River Basin governance from 1980 to 2022—based on semantic analysis method and punctuated equilibrium theory
Authors: Li Hao , Li Meng , Qin Yi , Ji Meiduo
Published: October 2024

The governance policies have a prominent impact on the development and regional planning of the Yangtze River Basin, a key region for China to achieve modernization. Taking the public policy documents issued by China’s central government for the Yangtze River Basin from 1980 to 2022 as the research object, this paper introduces the NLP (Natural Language Processing) technology and semantic analysis methods to carry out quantitative research on policies. This study first examines the textual connotations of the policies and the characteristics of the policy changes based on the LDA (Latent Dirichlet Allocation) model to determine how policy changes occur for the governance of the Yangtze River Basin. Using the punctuated equilibrium theory, it then conducts two case studies in which the implications of specific major events are analyzed in depth. Research has shown that the changes in governance policies for the Yangtze River Basin are characterized by gradual changes and intermittent mutation, roughly divided into three stages: the stage of reform and development, the stage of transition, and the stage of prioritizing ecological conservation and green development. Moreover, such changes jointly result from three factors: the major events, the focus of public opinions, and the care of the central government.
Passive Source Reverse Time Migration Based on the Spectral Element Method
Authors: He Bin , Chen Yu , Lei Ting , Lumley David , Liu Qinya , Takeuchi Nozomu , Kawakatsu Hitoshi , Zhu Hejun
Published: October 2024

Increasing deployment of dense arrays has facilitated detailed structure imaging for tectonic investigation, hazard assessment and resource exploration. Strong velocity heterogeneity and topographic changes have to be considered during passive source imaging. However, it is quite challenging for ray‐based methods, such as Kirchhoff migration or the widely used teleseismic receiver function, to handle these problems. In this study, we propose a 3‐D passive source reverse time migration strategy based on the spectral element method. It is realized by decomposing the time reversal full elastic wavefield into amplitude‐preserved vector P and S wavefields by solving the corresponding weak‐form solutions, followed by a dot‐product imaging condition to get images for the subsurface structures. It enables us to use regional 3‐D migration velocity models and take topographic variations into account, helping us to locate reflectors at more accurate positions than traditional 1‐D model‐based methods, like teleseismic receiver functions. Two synthetic tests are used to demonstrate the advantages of the proposed method to handle topographic variations and complex velocity heterogeneities. Furthermore, applications to the Laramie array data using both teleseismic P and S waves enable us to identify several south‐dipping structures beneath the Laramie basin in southeast Wyoming, which are interpreted as the Cheyenne Belt suture zone and agree with, and improve upon previous geological interpretations.
Propagation of Free Infragravity Waves Generated at Distant Beaches
Authors: Matsuba Yoshinao , Roelvink Dano , van Dongeren Ap
Published: October 2024

Infragravity (IG) waves are important drivers of extreme run‐up, morphological changes, and seiches. While locally forced IG waves have been extensively investigated, recent studies have revealed the significance of free IG waves generated on distant beaches. This study focuses on free IG waves generated at a coast facing southeast in Japan during the passage of a typhoon. The relationship between incident short waves and free IG waves as well as their contributions to nearshore IG waves, in particular to seiches in a small port, are analyzed using unique measurement data and numerical experiments. During the typhoon passage, more than 75% of the observed IG wave energy originates from free IG waves at an observatory located at a depth of 23 m, and their peak direction is alongshore. Six‐year measurement data demonstrate that peak directions of free IG waves strongly depend on the incident wave angles of short waves and that swells from the south generate alongshore propagating free IG waves. A numerical model can reproduce the alongshore propagating free IG waves accurately when using a large computational domain. Moreover, numerical experiments performed using the model demonstrate that the alongshore propagating free IG waves are IG waves reflected from distant beaches. The free IG waves from distant beaches are small outside the port, but seiches in the port are amplified by more than 10%. The relationship between seiches and incoming free IG waves is further discussed based on the numerical experiments.
Paired X‐Ray Micro CT Scanning and Individual Foraminifera Isotopic Analysis Reveal (De)coupled Changes in Carbonate Preservation and Temperature
Authors: Jana Debadrita , Torres Mark , Evans Kory , Jayan Ammoose K. , Thirumalai Kaustubh
Published: October 2024

The composition and preservation state of biogenic carbonate archives, such as foraminiferal tests, record ocean chemistry during the lifetime of the organism and post‐depositional changes in ambient conditions via carbonate compensation. Depending upon the specific paleoclimate proxy, post‐depositional processes, including dissolution, may alter original paleoenvironmental signals captured by the foraminifer's test composition. Accordingly, quantifying dissolution independent of geochemical measurements can improve proxy interpretation. Developing independent tools may also be useful for investigating whether changes in paleoclimatic conditions are associated with changes in seawater carbonate chemistry. Such approaches can be improved further if they are applied to individual foraminiferal tests, as specimen‐to‐specimen differences can record higher‐frequency environmental changes compared to conventional bulk‐scale analyses. Here, we combine individual foraminiferal carbon and oxygen isotopic analyses (IFA) with X‐ray MicroCT Scanning to generate paired analyses of test density (a proxy for the extent of post‐depositional dissolution) and isotopic composition. As a proof‐of‐concept application of this approach, we analyze Globigerina bulloides tests from both coretop and latest Miocene/earliest Pliocene‐aged sediment from Ocean Drilling Project (ODP) Site 1088 (Agulhas Ridge). Our measurements and mixing model calculations show that within‐population differences in carbon and oxygen isotopic ratios are largely independent of dissolution extent. By comparing population averages from coretop and downcore sediments, we find that lower oxygen isotopic ratios (likely driven by higher calcification temperatures) are associated with greater extents of dissolution at ODP Site 1088. We interpret this finding to reflect coupled changes in carbonate chemistry and climatic conditions over million‐year timescales.
Investigating Subsurface Properties of the Shallow Lunar Crust Using Seismic Interferometry on Synthetic and Recorded Data
Authors: Keil S. , Igel H. , Schimmel M. , Lindner F. , Bernauer F.
Published: October 2024

In the past few years, the remarkable progress of commercially operated spacecrafts, the success with reusable rocket engines, as well as the international competition to explore space, has led to a substantial acceleration of activities in the design and preparation of ambitious future lunar missions. In the search for ice and/or cavities imaging the shallow subsurface structure is of vital importance. Hereby, previous studies have shown that seismic interferometry is a promising method to investigate the subsurface properties from passive lunar data. In this study, we want to evaluate the potential of this method further by examining the required duration of seismic measurements and the influence of scattering on the Green's function retrieval. Therefore, we applied seismic interferometry to both measured Apollo 17 data and synthetic data. Our findings indicate that, under optimal conditions, a few hours of data are sufficient when using the method of time‐scaled phase‐weighted stack (ts‐PWS). However, this strongly depends on the inter‐station distance, the orientation toward the principal noise sources, and the timing of the measurement during the lunar cycle. Additionally, we were able to reproduce the measured data using numerical simulations in 2D. The synthetic results show that scattering effects clearly influence the Green's function extraction, especially for larger station distances.
An Ocean Memory Perspective: Disentangling Atmospheric Control of Decadal Variability in the North Atlantic Ocean
Authors: Khatri Hemant , Williams Richard G. , Woollings Tim , Smith Doug M.
Published: October 2024

An ocean memory framework is proposed to reveal the atmosphere's influence on ocean temperatures. Anomalous atmospheric forcing alters the ocean state through two mechanisms: short‐term, local effects involving airsea heat fluxes and Ekman circulation, and long‐term, far‐field effects involving changes from overturning and gyre circulations. The framework employs the Green function's method to incorporate both effects, enabling the quantification of ocean memory and the contribution of atmospheric forcing to ocean thermal variability. The framework is employed to examine the North Atlantic Oscillation's (NAO) influence on the North Atlantic Ocean variability, including the Atlantic Multidecadal Variability, with its memory estimated to be years. The NAO and variability in the North Atlantic jet speed explain up to 30% of ocean decadal variability, primarily driven by temporal changes in ocean heat transport. Therefore, decadal fluctuations in ocean temperatures cannot be accurately modeled solely as a passive response to stochastic atmospheric forcing.
Giant Kelvin‐Helmholtz (KH) Waves at the Boundary Layer of the Coronal Mass Ejections (CMEs) Responsible for the Largest Geomagnetic Storm in 20 Years
Authors: Nykyri Katariina
Published: October 2024

Starting in the evening of 10 May 2024 the Earth's magnetosphere was hit by the coronal mass ejections (CMEs) creating the largest geomagnetic storm in 20 years. The CME encounter was characterized by variations of plasma number density and magnetic field. Here, I present the ARTEMIS observations at the lunar orbit during this event. The IMF ranged from −60 to +40 nT both with hour to minutes periodicity with plasma jets propagating in ‐direction within multi‐scale wave structures. Similar signature has been recently reported at the magnetopause by MMS spacecraft (Li et al., 2023, https://doi.org/10.1029/2023GL105539; Nykyri, 2024, https://doi.org/10.1029/2024GL108605) during a strongly southward IMF. Here, I show that the CME boundaries were KH unstable leading to multi‐scale density and magnetic field fluctuations including reconnection jets. The wavelengths varied from 60 to 270 , suggesting that the magnetosphere was periodically exposed to successive intervals of strongly northward and southward IMF leading to enhanced mass and magnetic flux loading.
Scaling Individual Tree Transpiration With Thermal Cameras Reveals Interspecies Differences to Drought Vulnerability
Authors: Javadian Mostafa , Aubrecht Donald M. , Fisher Joshua B. , Scott Russell L. , Burns Sean P. , Diehl Jen L. , Munger J. William , Richardson Andrew D.
Published: October 2024

Understanding tree transpiration variability is vital for assessing ecosystem water‐use efficiency and forest health amid climate change, yet most landscape‐level measurements do not differentiate individual trees. Using canopy temperature data from thermal cameras, we estimated the transpiration rates of individual trees at Harvard Forest and Niwot Ridge. PT‐JPL model was used to derive latent heat flux from thermal images at the canopy‐level, showing strong agreement with tower measurements (R2 = 0.70–0.96 at Niwot, 0.59–0.78 at Harvard at half‐hourly to monthly scales) and daily RMSE of 33.5 W/m2 (Niwot) and 52.8 W/m2 (Harvard). Tree‐level analysis revealed species‐specific responses to drought, with lodgepole pine exhibiting greater tolerance than Engelmann spruce at Niwot and red oak showing heightened resistance than red maple at Harvard. These findings show how ecophysiological differences between species result in varying responses to drought and demonstrate that these responses can be characterized by deriving transpiration from crown temperature measurements.
The Evolution of Rock Size‐Frequency Distribution on the Moon: Effects of Rock Strength and Fragmentation Products on Centimeter‐Scale Abundances
Authors: Rüsch O. , Aussel B.
Published: October 2024

Rock abundances on the Moon represent both an opportunity to understand the history of the surface and of the regolith and a hazard to lander missions. While rock erasure by meteoroid bombardment is known to modify rock size˗frequency distributions, the interplay between rock erasure and rock exposure by impact cratering, and the resulting net rock abundance, is not known. Leveraging a coupling between modeling and optical imagery from the lunar orbit, we calculate new rock lifetimes that consider the specific shattering energy and the fragments produced by boulder shattering. We find differences between the estimated and expected specific shattering energy (Qs*), likely suggesting incomplete understanding of the scaling of the shattering energy with velocity and size. We find that the decrease in rock abundances with time on crater ejecta occurs faster than previous estimates based on thermal infrared data.