bluuebunny/crossref_metadata_2025 huggingface dataset:
The Unreliability of Place Construction in Contemporary Alaskan Regional Writing // La falta de fiabilidad en la construcción del lugar en la narrativa regional contemporánea de Alaska
Authors: Feuer-Cotter Julia
Published: April 2020

Alaska’s geographic isolation results in the fact that most people experience the Far North only second-hand, commonly from the narratives of visitors. Those representations, overshadowed by myth, define Alaska as a region and reflect on the literary imagination of the 49th state. This paper analyses the reader’s image of Alaska and its inhabitants by tracing how regional narratives are perceived by scholars and reviewers, paying attention to the historically different transatlantic perceptions of indigenous peoples and Arctic nature. It becomes clear that Alaska as a setting, as described by its inhabitants, relies on imposed qualities that depend on the self-perception of the outside observer and not on the narration. The contested narrations of Velma Wallis and Sheila Nickerson help to position Alaska as a stage for the struggle over the spatial meaning carried out between outsiders. Conscious of this power struggle and its importance, these contemporary regional authors engage in the discourse over Alaska’s representation by narrating its unreliability. These authors produce texts that invite different readings to foster a cultural discourse about the meaning of the Alaskan place within the national identity and policies. Resumen El aislamiento geográfico de Alaska se debe al hecho de que la mayoría de las personas experimentan el extremo Norte sólo de segunda mano, normalmente a partir de los relatos de visitantes. Esta representación, eclipsada por una larga tradición de mitos, define a Alaska como región y se refleja en la imaginación literaria del estado 49º. Este artículo analiza el paradigma del lector de Alaska y de sus habitantes a través del estudio de cómo los estudiosos y críticos no-académicos perciben las narrativas acerca de dicha región, prestando atención a las percepciones transatlánticas históricamente diferentes de los pueblos indígenas y la naturaleza ártica. Es evidente que Alaska, como lugar descrito por sus habitantes, se basa en cualidades impuestas que dependen de la auto-percepción del lector foráneo y no en la narración. Los escritos de Velma Wallis and Sheila Nickerson colaboran en posicionar a Alaska como un escenario para la lucha sobre el significado espacial producido por los observadores foráneos. Conscientes de esta lucha por el poder y su importancia, estas autores regionales contemporáneas participan en este discurso narrando la falta de fiabilidad de la memoria, el lenguaje y la representación. En lugar de escribir en contra de la imaginación espacial, producen textos que sugieren lecturas que fomentan un discurso cultural acerca del significado de Alaska.
Editorial
Authors: Iovino Serenella
Published: April 2020

Editorial
Dos poemas // Two Poems
Authors: Brintrup Hertling Lilianet
Published: April 2020

Resumen      Poemas. Abstract      Poems.
Editorial
Authors: Iovino Serenella
Published: April 2020

Editorial for the Creative Writing and Arts section.
Editorial
Authors: Goodbody Axel Howarth
Published: April 2020

Editorial
Филология – враг лингвистики
Authors: Zimmerling A.V.
Published: April 2020

Лингвистика автономная от филологии наука, а не часть филологии. Объект филологии текст как фиксированная вербальная форма и классификация жанров. Объект лингвистики механизмы языка, реализующиеся автоматически. Филология гуманитарная наука, лингвистика естественная. Максимальной единицей языка является предложение. Так называемая лингвистика текста, связывающая параметры предложения с особенностями текста, в рамках дихотомии лингвистика vs филология может быть определена как скрытая филология, т.е. область, где лингвистические методы используются для решения традиционных задач филологии.

I argue that linguistics and philology are sciences of a different type. Philology deals with texts as fixed verbal forms and with genre classifications. Linguistics deals with the mechanisms of language structure realized automatically. Philology is an art science, linguistics is a natural science. So called text linguistics i.e. a branch explaining the links between clausal features and text features must be redefined as cryptophilology. Cryptophilogists apply a part of the linguistic methods but solve traditional philological problems.
Возможности организации логопедического онлайн-консультирования русскоязычных семей за рубежом
Authors: Rusetskaya M.N. , Lagutina A.V. , Velichenkova O.A.
Published: April 2020

Статья посвящена проблеме организации дистантного логопедического консультирования русскоязычных семей за рубежом. Обсуждаются основные проблемы, возникающие в ходе дифференциальной диагностики речевых нарушений и особенностей речевого развития, обусловленных естественным билингвизмом. Предложена общая схема онлайн-консультирования родителей и преподавателей русского языка по вопросам речевого развития двуязычных детей.

The article considers the problem of organizing distant speech therapy counseling for Russian-speaking families abroad. The main problems arising in the course of differential diagnosis of speech disorders and features of speech development caused by natural bilingualism are discussed. The General scheme of online counseling of parents and teachers of the Russian language on the issues of speech development of bilingual children is proposed.
ВОХМИНА Л.Л., КУВАЕВА А.С., ХАВРОНИНА С.А. СИСТЕМА УПРАЖНЕНИЙ ПО ОБУЧЕНИЮ УСТНОЙ ИНОЯЗЫЧНОЙ РЕЧИ: ТЕОРИЯ И ПРАКТИКА (НА ПРИМЕРЕ РКИ) СПб.: Златоуст, 2020. – 268 с.
Authors: Molchanovskiy V.V.
Published: April 2020

В статье представлено описание структуры и содержания книги Система упражнений по обучению устной иноязычной речи: теория и практика (на примере РКИ) Л.Л. Вохминой, А.С. Куваевой, С.А. Хаврониной. Книга рассматривает широкий круг проблем, связанных с историей, развитием и современным состоянием вопроса о создании упражнений по обучению устной иноязычной речи. Как результат изучения предыдущего опыта и собственной практики предложена оригинальная система упражнений, построенная напринципе перехода от простого к сложному в соответствии с психолингвистическими процессами формирования устной речи. Данная работа может быть интересна широкому кругу читателей, связанных с преподаванием иностранных языков, включая русский.

The article describes the structure and content of the bookSystem of Exercises for Oral Foreign Language Teaching: Theory and Practice (on the Example of RLT)by L.L. Vokhmina, A.S. Kuvaeva, S.A. Khavronina. The book examines a wide range of problems related to the history, development and current state of the problem of exercises for oral foreign language teaching. As a result of studying previous experience and own practice an original system of exercises is proposed, built on the principle of transition from simple to complex in accordance with the psycholinguistic processes of oral speech formation. This work may be of interest to a wide circle of readers related to the teaching of foreign languages including Russian.
A “STRANGENESS IN MY MIND” BY ORHAN PAMUK – HOW THE NOVEL IS MADE
Authors: RAKYOVSKI Tsvetan
Published: April 2020

e article explores the diversity of narrative techniques in Orhan Pamuk’s novel A Strangeness in My Mind. The main idea is that the drama of a private life is told against the background of the drama of the life of Istanbul. To do this, the novel parallels the biographical ‘I’ of the main character and the historical ‘He’ of the City. This comparison provokes the idea of the novel’s close relation to the history of Istanbul and Turkey over the last fifty years. Orhan Pamuk does not spare the reader any of the specific, purely "Turkish problems" with the Kurds and Greeks, as well as the radical and conservative moods and public discontent from the 1950s to the 1980s. The narrative line is developed slowly and minutely,owing to the author's intention to authenticate real events through the perspective of fictional characters and vice versa - to romanticize cultural and purely civilizational processes in the last half century of the development of this part of the border between Europe and Asia. This is the only way to explain the presence of the problem of women's emancipation and the lack of that misunderstood "patriotism" which often prevents the depiction of purely national processes in life. This refutes the widespread opinion that A Strangeness in My Mind is a postmodern novel.
TEACHING FOREIGN LANGUAGES IN THE CONTEXT OF COGNITIVE AND CONCEPTUAL PRIORITIES OF MODERN EDUCATION
Authors: BARTOSH Dana , STOYANOVA Elena , GALSKOVA Natalya , PETKOVA-KALEVA Stefk
Published: April 2020

The purpose of this paper is to consider the problems of teaching foreign languages as one of the priorities of the modern educational process at different levels. The paper focuses on the priority of the humanitarian paradigm and the impact of the linguocultural situation and the linguistic and cultural environment on the formation of the educational environment and personal development in modern conditions, the similarity of key skills and trends in the development of the educational system in Bulgaria and Russia is established. The cognitive-communicative approach to teaching foreign languages, based on the development and activation of cognitive mechanisms of students and the modernization of the educational environment using cognitive techniques and technologies, determines the effectiveness and quality of teaching foreign languages. Foreign language competence is a necessary and integral part of the communicative competence of an educated person in the modern world. Special attention in thе paper is paid to the specifics of teaching a foreign language (as opposed to the native /or the second native one) outside the sphere of communication.The further development of foreign languageteaching methods of various types of monasticism, in our opinion, will provide not only mastery of the language, but also its successful assimilation.
PERUBAHAN IKLIM DAN DEMOKRASI: KETERSEDIAAN DAN AKSES INFORMASI IKLIM, PERANAN PEMERINTAH, DAN PARTISIPASI MASYARAKAT DALAM MENDUKUNG IMPLEMENTASI ADAPTASI PERUBAHAN IKLIM DI INDONESIA
Authors: Perdinan Perdinan
Published: April 2020

Perubahan iklim merupakan fenomena iklim global yang dipicu dengan adanya pemanasan global akibat kenaikan konsentrasi gas-gas rumah kaca di atmosfer. Memahami dampak perubahan iklim terhadap berbagai sektor ekonomi di Indonesia, pemerintah Indonesia merespon melalui berbagai kebijakan yang dituangkan dalam Undang-Undang dan Peraturan Pemerintah. Tulisan ini membahas mengenai „posisi‟ kebijakan terkait adaptasi perubahan iklim di Indonesia. Tantangan dalam pelaksanaan adaptasi perubahan iklim juga dibahas berdasarkan studi pustaka dan interpretasi dari dokumen-dokumen terkait adaptasi perubahan iklim. Pembahasan juga dilakukan terkait ketersediaan dan akses informasi iklim yang sangat diperlukan dalam penilaian dampak perubahan iklim sebagai langkah awal dalam penyusunan langkahlangkah adaptasi. Hasil telaah menunjukkan ketersediaan dan kemudahan akses terhadap data hasil pengamatan iklim (observasi) masih menjadi pekerjaan rumah yang perlu mendapatkan perhatian. Peran aktif masyarakat dalam kegiatan-kegiatan pengamatan dan pengumpulan informasi iklim sangat diperlukan mengingat ketersediaan informasi iklim yang masih terbatas.Kerjasama antara Pemerintah Pusat dan daerah serta partisipasi publik dalam program-program adaptasi juga dianjurkan dan sangat diperlukan.
PARTISIPASI MASYARAKAT DALAM PENGELOLAAN WILAYAH PESISIR DI ACEH
Authors: Safrina Safrina
Published: April 2020

Abstrak Partisipasi masyarakat dalam perlindungan dan pengelolaan lingkungan hidup telah menjadi agenda negara-negara di dunia terutama setelah menjadi salah satu prinsip dalam Deklarasi Rio 1992. Indonesia melalui Undang-Undang Nomor 32 Tahun 2009 tentang Perlindungan dan Pengelolaan Lingkungan Hidup mencantumkan prinsip partisipatif sebagai salah satu asas dalam penyusunan setiap kebijakan terkait lingkungan hidup. Tulisan ini bertujuan untuk memaparkan pelaksanaan Program Pengelolaan Wilayah Laut Berbasis masyarakat pada Masyarakat Ujong Pancu, Kabupaten Aceh Besar dan memahami bagaimana peran institusi adat laot (Panglima Laot) dalam pengelolaan lingkungan pesisir. Perlindungan dan pengelolaan wilayah pesisir di Aceh dilakukan dengan menggunakan dua pendekatan, yaitu melalui pembentukan aturan hukum yang mendukung dan penguatan kapasitas institusi masyarakat, institusi adat dan hukum adat yang dipercaya dapat menjadi wadah yang efektif untuk melibatkan masyarakat dalam proses pembangunan. Melalui program tersebut masyarakat terlibat secara langsung dalam penentuan kawasan konservasi laut dan juga ikut menentukan langkah-langkah yang terbaik untuk melindungi kawasan pesisir tempat mereka menetap. Lebih lanjut, melalui pengelolaan wilayah pesisir berbasis masyarakat dapat meminimalkan dampak negatif dari pembangunan dan memungkinkan masyarakat untuk memperoleh informasi yang berimbang dan obyektif sehingga dapat memberikan kontribusi untuk pemecahan masalah-masalah lingkungan. Abstract Community participation in protection and management of the environment has been on the agenda of countries in the world, especially after incorporated as a principle in the Rio Declaration of 1992. Indonesia, through Law No. 32 of 2009 on the Environmental Protection and Management included participatory principle in policy-making related to the environment. This study aims to examine the implementation of community participation in coastal management and to analyze the role of adat institution (Panglima Laot) in managing the coastal environment in Aceh. Protection and management of coastal areas in Aceh is conducted under two approaches, namely the establishment of the regulations that support the implementation process and strengthening the capacity of public institutions; and traditional institutions and customary laws that are believed can be an effective way to engage community in the development process. Through a program of community-based coastal management, community directly involved in determining the marine conservation areas and also determine the best steps to protect their region. Moreover, the program can also minimize the negative impacts of development and enable public to obtain a balanced and objective information that can contribute to solve the problems in their environment.
Anotasi Putusan Perkara Tata Usaha Negara antara Kuat, cs. melawan Pemerintah DK I Jakarta tentang Pembatalan Izin Pelaksanaan Reklamasi Pulau G (No. 193/G/LH/2015/PTUN-JKT)
Authors: Dudayev Rayhan
Published: April 2020

Selasa, 31 Mei 2016 merupakan hari yang menandai kemenangan NelayanMuara Angke terhadap gugatan yang mereka lakukan terhadap Izin PelaksanaanReklamasi Pulau G di Teluk Jakarta. Lima orang nelayan bersama dua organisasilingkungan hidup, Wahana Lingkungan Hidup Indonesia (Walhi) dan KoalisiRakyat untuk Keadilan Perikanan (KIARA) mengajukan gugatan terhadap SKGubernur DKI Jakarta No. 2238 Tahun 2014 di Pengadilan Tata Usaha Negara(TUN) Jakarta. Pasca tujuh bulan berselang, ketua majelis hakim, Adhi BudhiSulistyo yang merupakan hakim lingkungan, mengabulkan gugatan nelayan danmenyatakan batal atau tidak sah SK yang dikeluarkan gubernur tersebut.
Tata Kelola Pertambangan dalam Kerangka Indonesia Incorporated untuk Mewujudkan Negara Kesejahteraan
Authors: Wijoyo Suparto
Published: April 2020

Aspek yuridis tata kelola pertambangan diformulasi memberikan konstruksi baru yang solutif bagi kesejahteraan rakyat. Tata kelola pertambangan yang baik dapat menjadikan Indonesia sebagai superkoridor ekonomi dunia melalui implementasi konsepsi Indonesia Incorporated.
Peraturan Presiden Nomor 22 Tahun 2017 tentang Rencana Umum Energi Nasional
Authors: Widyaningsih Grita Anindarini
Published: April 2020

Tulisan ini membatasi pembahasan kepada kebijakan dan strategi pengelolaan energinasional serta isu-isu terkait perlindungan dan pengelolaan lingkungan hidupyang tercantum dalam Perpres RUEN
Analisis Terhadap Sertifikasi Minyak Kelapa Sawit Berkelanjutan Sebagai Instrumen Penaatan Hukum Lingkungan
Authors: Indrapraja Fadhil Muhammad
Published: April 2020

Minyak kelapa sawit merupakan komoditas yang digunakan untuk berbagai macam produk, seperti minyak goreng, margarin, kosmetik, dan bahan bakar hayati. Didorong oleh tuntutan global, permintaan pasar terhadap minyak kelapa sawit di berbagai belahan dunia membuat kelapa sawit menjadi sumber minyak nabati terbesar. Perkembangan produksi minyak kelapa sawit tersebut memberikan dampak ekonomi yang positif. Kendati demikian, perkembangan produksi minyak kelapa sawit juga berdampak negatif terhadap lingkungan dan kehidupan sosial. Salah satu upaya yang dilakukan untuk mengantisipasi dampak negatif tersebut adalah dengan menerapkan standar minyak kelapa sawit berkelanjutan melalui sistem sertifikasi. Penelitian ini mencoba untuk mengkaji secara normatif tiga sistem sertifikasi minyak kelapa sawit berkelanjutan, yaitu Sertifikasi Roundtable on Sustainable Palm Oil, Sertifikasi Indonesian Sustainable Palm Oil, dan Sertifikasi Malaysian Sustainable Palm Oil sebagai instrumen penaatan hukum lingkungan. Hasil penelitian dalam tulisan ini menunjukkan bahwa ketiga sistem sertifikasi tersebut belum optimal sebagai instrumen penaatan hukum lingkungan. Untuk itu, ketiga sistem sertifikasi tersebut perlu disempurnakan.
Rancang Bangun Aplikasi QR Code Berbasis Android Pada Perpustakaan Akademi Komunitas Negeri Putra Sang Fajar Blitar
Authors: Fu'ad M. Nur , Kholil Moch , Wardhani Shanti Ike
Published: April 2020

Abstrak— Perpustakaan bermanfaat untuk memajukan dan melestarikan kebudayaan serta merupakan fasilitas penting dalam keberhasilan proses pendidikan. Namun perpustakaan Akademi Komunitas Negeri Putra Sang Fajar Blitar belum tersistem sehingga pengelolaan dan pelayanan perpustakaan masih dilakukan secara manual dengan pencatatan transaksi peminjaman dan pengembalian secara tertulis. Dibutuhkan sistem peminjaman dan pengembalian yang tepat guna untuk meningkatkan pelayanan perpustakaan. Teknologi QR Code menjadi salah satu solusi dengan didukung sistem operasi Android, QR Code digunakan sebagai kode buku yang akan dicatat dalam transaksi peminjaman dan pengembalian. Uji coba aplikasi membuktikan bahwa transaksi peminjaman dan pengembalian dengan aplikasi QR Code perpustakaan lebih cepat daripada manual. Lama waktu rata-rata transaksi untuk 1, 3 dan 5 buku dengan aplikasi QR Code perpustakaan adalah 4,9 detik, 14,7 detik dan 23,2 detik.Kata kunci: QR Code, Android, aplikasi  perpustakaanAbstract— The library is useful for promoting and preserving culture and becomes an important facility in the education process. But the library of Akademi Komunitas Negeri Putra Sang Fajar Blitar has not been systemized so that library management and services are still done manually by recording borrow and return transactions in writing. An appropriate borrows and returns system is needed to improve library services. QR Code technology is one of the solutions supported by Android operating system, QR Code is used as a book code that will be recorded in the borrows and returns transaction. Test of application prove that borrow and return transactions with the library QR Code application is faster than manual. Average transaction time for 1, 3 and 5 books are 4.9 seconds, 14.7 seconds and 23.2 seconds respectively.Keywords: QR Code, Android, library application
TESTING FOR COMPLETE PASS-THROUGH OF EXCHANGE RATE WITHOUT TRADE BARRIERS
Authors: Zhang Tengfei , Li Tianxiang , Baležentis Tomas , Štreimikienė Dalia
Published: April 2020

The objective of this paper is to test whether the complete pass-through of exchange rate exists when there are almost no transaction costs and in the environment of competitive market. In general, the literature claims that the pass-through of exchange rate is incomplete due to imperfect market, i.e. the presence of transaction costs and imperfect competition. The quasi-experimental case of the food import to Hong Kong from Mainland China is considered in the analysis. The results show that the pass-through of the exchange rate of Chinese RMB against to US dollar to Hong Kong’s food import price is complete in long-run equilibrium. Besides, the short-run adjustment significantly contributes to correcting the deviation from the long-run pass-through effect. Moreover, the complete pass-through still exists after accounting for the effects of asymmetry and volatility. Therefore, this paper contributes to the literature by providing empirical evidence that the complete pass-through of exchange rate can exist in the real world.
When Gas Dynamics Decouples from Galactic Rotation: Characterizing ISM Circulation in Disk Galaxies
Authors: Utreras José , Blanc Guillermo A. , Escala Andrés , Meidt Sharon , Emsellem Eric , Bigiel Frank , C. O. Glover Simon , Henshaw Jonathan , Hygate Alex , Kruijssen J. M. Diederik , Rosolowsky Erik , Schinnerer Eva , Schruba Andreas
Published: April 2020

In galactic disks, galactic rotation sets the bulk motion of gas, and its energy and momentum can be transferred toward small scales. Additionally, in the interstellar medium, random and noncircular motions arise from stellar feedback, cloud–cloud interactions, and instabilities, among other processes. Our aim is to comprehend to what extent small-scale gas dynamics is decoupled from galactic rotation. We study the relative contributions of galactic rotation and local noncircular motions to the circulation of gas, Γ, a macroscopic measure of local rotation, defined as the line integral of the velocity field around a closed path. We measure the circulation distribution as a function of spatial scale in a set of simulated disk galaxies and model the velocity field as the sum of galactic rotation and a Gaussian random field. The random field is parameterized by a broken power law in Fourier space, with a break at the scale

. We define the spatial scale

at which galactic rotation and noncircular motions contribute equally to Γ. For our simulated galaxies, the gas dynamics at the scale of molecular clouds is usually dominated by noncircular motions, but in the center of galactic disks galactic rotation is still relevant. Our model shows that the transfer of rotation from large scales breaks at the scale

, and this transition is necessary to reproduce the circulation distribution. We find that

, and therefore the structure of the gas velocity field, is set by the local conditions of gravitational stability and stellar feedback.
Dusty Stellar Birth and Death in the Metal-poor Galaxy NGC 6822
Authors: Hirschauer Alec S. , Gray Laurin , Meixner Margaret , Jones Olivia C. , Srinivasan Sundar , Boyer Martha L. , Sargent B. A.
Published: April 2020

The nearby (∼500 kpc) metal-poor ([Fe/H] ≈ –1.2; Z ≈ 30% Z
⊙) star-forming galaxy NGC 6822 has a metallicity similar to systems at the epoch of peak star formation. Through identification and study of dusty and dust-producing stars, it is therefore a useful laboratory to shed light on the dust life cycle in the early universe. We present a catalog of sources combining near- and mid-IR photometry from the United Kingdom Infrared Telescope (J, H, and K) and the Spitzer Space Telescope (IRAC 3.6, 4.5, 5.8, and 8.0 μm and MIPS 24 μm). This catalog is employed to identify dusty and evolved stars in NGC 6822 utilizing three color–magnitude diagrams (CMDs). With diagnostic CMDs covering a wavelength range spanning the near- and mid-IR, we develop color cuts using kernel density estimate (KDE) techniques to identify dust-producing evolved stars, including red supergiant (RSG) and thermally pulsing asymptotic giant branch (TP-AGB) star candidates. In total, we report 1292 RSG candidates, 1050 oxygen-rich AGB star candidates, and 560 carbon-rich AGB star candidates with high confidence in NGC 6822. Our analysis of the AGB stars suggests a robust population inhabiting the central stellar bar of the galaxy, with a measured global stellar metallicity of [Fe/H] = −1.286 ± 0.095, consistent with previous studies. In addition, we identify 277 young stellar object (YSO) candidates. The detection of a large number of YSO candidates within a centrally located, compact cluster reveals the existence of an embedded, high-mass star formation region that has eluded previous detailed study. Spitzer I appears to be younger and more active than the other prominent star-forming regions in the galaxy.
Enabling Catalog Simulations of Transient and Variable Sources Based on LSST Cadence Strategies
Authors: Biswas Rahul , Daniel Scott F. , Hložek R , Kim A. G. , Yoachim Peter ,   (LSST Dark Energy Science Collaboration)
Published: April 2020

The Large Synoptic Survey Telescope (LSST) project will conduct a 10 year multi-band survey starting in 2022. Observing strategies for this survey are being actively investigated, and the science capabilities can be best forecasted on the basis of simulated strategies from the LSST Operations Simulator (OpSim). OpSim simulates a stochastic realization of the sequence of LSST pointings over the survey duration, and is based on a model of the observatory (including telescope) and historical data of observational conditions. OpSim outputs contain a record of each simulated pointing of the survey along with a complete characterization of the pointing in terms of observing conditions, and some useful quantities derived from the characteristics of the pointing. Thus, each record can be efficiently used to derive the properties of observations of all astrophysical sources found in that pointing. However, in order to obtain the time series of observations (light curves) of a set of sources, it is often more convenient to compute all observations of an astrophysical source, and iterate over sources. In this document, we describe the open source python package OpSimSummary, which allows for a convenient reordering. The objectives of this package are to provide users with an Application Programming Interface for accessing all such observations and summarizing this information in the form of intermediate data products usable by third party software such as SNANA, thereby also bridging the gap between official LSST products and preexisting simulation codes.
Short-Term Neuropsychiatric Tolerability of Bictegravir Combined with Emtricitabine/Tenofovir Alafenamide in Clinical Practice
Authors: Hoffmann Christian , Schewe Knud , Fenske Stefan , Buhk Thomas , Sabranski Michael , Adam Axel , Hansen Stefan , Stellbrink Hans-Jürgen
Published: April 2020

Background

Neuropsychiatric AEs (NPAEs) leading to dolutegravir (DTG) discontinuation were seen more frequently in real-world use than in randomized clinical trials (RCTs). The recently approved fixed-dose combination bictegravir plus emtricitabine and tenofovir alafenamide (BIC/F/TAF) has shown comparable NPAE rates but some favourable patient-reported outcomes in RCTs compared with DTG. We were interested in its neuropsychiatric tolerability in clinical practice.

Methods

All patients starting BIC/F/TAF from June 2018 in a single centre (two subcentres) were followed retrospectively. Discontinuation rates due to any AEs and NPAEs were compared with those of patients initiating DTG-based regimens.

Results

As of May 2019, a total of 943 patients (852 males, 76 females, 15 transgender and gender diverse) initiated BIC/F/TAF outside RCTs. After a median follow-up of 6.2 months, 50 (5.3%) and 31 (3.3%) patients had discontinued BIC/F/TAF due to any AEs or to NPAEs, respectively. In multivariate analysis, a pre-existing depression and subcentre remained predictive for NPAEs, but not age, gender, ethnicity or prior DTG-related AEs. Compared with 1,043 patients treated with DTG-based regimens, the estimated NPAE-related discontinuation rate with BIC/F/TAF was comparable during the first 6 months ( P=0.36). Cross-intolerance was low, and only 5/55 patients with prior DTG intolerability had to discontinue BIC/F/TAF due to NPAEs.

Conclusions

Short-term tolerability of BIC/F/TAF was comparable to DTG-containing regimens. As seen with DTG, discontinuation rates were higher than in RCTs. A pre-existing depression but also physician's awareness may have an impact on tolerability and continuation of BIC/F/TAF. In contrast, prior intolerability of DTG was of limited predictive value.
The effect of Attention Deficit and Hyperactivity Disorder on Antiretroviral Treatment and Appointment Adherence among adults living with HIV
Authors: Uysal Serhat , Elbi Hayriye , Mermut Gülşen , Onen Sertoz Ozen , Kaptan Figen , Gülpek Demet , Gokengin Deniz
Published: April 2020

Introduction: The most prominent characteristic of adult attention deficit hyperactivity disorder (ADHD) is impulsive behavior and deficits in executive functions, which require long-term organization and discipline. This may have serious implications in terms of adherence to treatment among adults living with HIV (PLWH). This study aimed to determine the prevalence of ADHD among non-perinatally infected PLWH and its effect on adherence to antiretroviral treatment (ART) and scheduled appointments.

Methodology: The PLWH admitted to our centers between January 2012 and February 2016 were invited to the study. ADHD diagnosis was made according to the novel criteria guided interviews. The first ART interruption for ≥ 6 days per month (≤ 80%) was defined as ‘‘ART-event’’ and the first non-attendance of any scheduled appointment was defined as ‘‘appointment-event’’. Kaplan-Meier plot with a Log-rank test was used for event-free adherence (EFA).

Results: Twenty-five patients out of 85 were diagnosed with ADHD (29.4 %) which was significantly higher than the highest percentage reported (7.3 %) for the general population (p < 0.0001). Both ART-event (p = 0.0002) and appointment-event (p = 0.02) were significantly higher among ADHD participants compared to those without. Additionally, both ART-EFA (p = 0.00014) and appointment-EFA (p = 0.023) were significantly shorter among ADHD participants compared to those without.

Conclusion: ADHD is significantly higher in adult PLWH and people with ADHD had a significant tendency for non-adherence to ART and follow-up. Screening for ADHD as well as providing treatment when required would be beneficial to achieve and maintain virologic success.
Antibiotic resistance pattern of Escherichia coli isolates from outpatients with urinary tract infections in Somalia
Authors: Mohamed Malyun Adam , Abdifetah Omar , Hussein Fatima Abdullahi , Karie Sa’adia Abdullahi
Published: April 2020

Introduction: Several studies suggest increasing rates of antibiotic resistance among adult populations with Urinary tract infections (UTI). Escherichia coli (E. coli), is the predominant bacterium both in the community and in hospital environments causing uropathogenic infections. This study aimed to estimate the common uropathogen bacteria that cause UTI among outpatients as well as to determine the antibiotic resistance pattern of E. coli isolates among outpatients with UTI infections at Shaafi hospital, Mogadishu, Somalia.

Methodology: A cross-sectional study was conducted at Shaafi Hospital, Mogadishu, Somalia. A total of 128 samples were collected from outpatients suspected of UTI and tested through bacteriological investigations and antimicrobial susceptibility tests following the Kirby-Bauer agar disc diffusion method.

Results: E. coli was isolated in 34 (41%) out of the total 83 samples that showed growth followed by Staphylococcus aureus 22 (26.5%), Pseudomonas aeruginosa, 13 (15.7%), Klebsiella pneumoniae 8 (9.6 %) and Proteus spp. 6 (7.2%). E. coli was highly sensitive to nitrofurantoin, 29 (85.3%), and ciprofloxacin (n = 23, 67.6%), and had the highest resistance rate of ceftriaxone, 33 (97.1%). The odds of having UTI were higher in patients with a history of UTI (Odds ratio OR = 0.211, 95% confidence interval CI: 0.080, 0.553) and history of antibiotic use (OR = 0.322, 95% CI: 0.113, 0.917). Increased resistance rate of E. coli against cephalosporins could be due to its excessive use as empirical therapy.

Conclusion: The study indicates that outpatients with UTI could be at high risk of antibiotic resistance, suggesting regular surveillance and monitoring of antibiotics.
Lenalidomide for the Treatment of Myelodysplastic Syndrome
Authors: Kim Sung-Yong
Published: April 2020

Myelodysplastic syndrome (MDS) is a disease affecting clinically and cytogenetically diverse groups of patients. Consequently, MDS patients differ in their response to the individual agents used to treat their disease. Lenalidomide, which has been covered by the national health insurance system of Korea since 2019, is used to relieve transfusion-dependent anemia and has been shown to achieve a genetic response in MDS patients, especially those carrying the del(5q) mutation. Although the mechanism of action of lenalidomide is not yet clear, it may block malignant cell proliferation directly by inhibiting haplodeficient phosphatase, but also act indirectly by killing malignant cells through an immunomodulatory effect. In clinical studies, low-risk patients with the del(5q) mutation who were treated with lenalidomide had a hematologic response rate of 55–60% and a median survival of 2–2.5 years. The genetic response rate was 50–73%, and the complete genetic response rate 30–45%. However, in high-risk patients, the response rate was low (20–30%). These results demonstrate the potential utility of lenalidomide as a first-line drug for transfusion-dependent, del(5q), low-risk patients in Korea.
« C’est un roman d’amour vécu qui vaut bien ceux qu’on invente » Louise et Georges Renard, amour et politique
Authors: Fabre Mélanie
Published: April 2020

En partie fondé sur l'analyse de la riche correspondance que Louise et Georges Renard ont entretenue au cours de leur liaison adultère, cet article s'emploie à étudier les liens entre leur expérience amoureuse et leur conception du couple. Ce travail interroge aussi la façon dont Louise Renard, méconnue de l'historiographie, acquiert, au contact de son second mari, une véritable stature intellectuelle. Libres penseurs, socialistes, féministes, Louise et Georges Renard partagent un combat en faveur de la réforme du mariage, qu'ils considèrent comme indispensable à toute réforme sociale. Ce texte s'attache à démêler les fils de l'élaboration d'une production intellectuelle et d'un engagement communs.
Del clero para el pueblo. La Literatura Edificante de Postguerra: un instrumento de divulgación y socialización religiosa
Authors: Roca i Girona Jordi
Published: April 2020

El artículo se ocupa del análisis de la que hemos denominado Literatura Edificante de Postguerra (L.E.P.). Se trata de un tipo de producción literaria específica dentro de la más amplia de carácter religioso, caracterizada por su objetivo divulgador del discurso oficial de la jerarquía eclesiástica de la época. Precisamente, la referencia temporal que se incluye en la denominación de esta literatura se justifica por el hecho de que ésta se inscribe, como un elemento más, en el contexto de la ofensiva socializadora del catolicismo tradicional que se dará, de forma especialmente destacada y duradera, durante la postguerra española. A pesar de ello, se trata de un fenómeno no exclusivamente español, como lo prueba la numerosa presencia de autores de diversos países del mundo católico occidental. Los autores, por cierto, poca consideración obtendrán en una literatura que se define como instrumento al servicio de la transmisión de un mensaje. El mensaje, a su vez, focalizará su atención en la sexualidad orientada a la procreación, por lo que no puede sorprender que se trate de una literatura dirigida especialmente a las mujeres y a los jóvenes, que serán, pues, sus principales lectores o, mejor dicho, compradores, puesto que por sus características peculiares la L.E.P. acabará constituyéndose en un potente símbolo de identificación y comunicación.
La tradición religiosa al servicio del folklorismo
Authors: Martí i Pérez Josep
Published: April 2020

Difícilmente podríamos llegar en la actualidad a comprender las diferentes manifestaciones de la cultura tradicional sin tener en cuenta las implicaciones formales, semánticas y funcionales del folklorismo, entendiendo este último término como todo aquello que hace relación al uso que se hace del folklore, una vez la sociedad ha devenido consciente de su existencia. Dado que el mundo de la vida tradicional está profusamente impregnado de formas y contenidos procedentes del ámbito religioso, las manifestaciones de la religiosidad popular también son objeto de la práctica folkloristica de nuestra sociedad. El análisis de esta problemática constituye el eje central del presente artículo.
Investigation on the Fabrication and Properties of the Cu Base Friction Composites
Authors: Wang Tian Guo , Liu X.Y. , Hua J.J.
Published: April 2020

Cu-based friction materials were prepared by powder metallurgy technology. The effect of Fe content on friction and wear properties of Cu-based friction materials has been investigated. The results indicate that Fe content has great effects on the wear ability of Cu-based friction materials. Fe works as frictional component in copper-based friction materials, influening the mechanical and frictional property of materials. With increasing Fe content, the hardness and friction coefficient of Cu-based friction materials stability increase, the wear rate of the friction materials decreases. When Fe content is 6%, the materials posses stably high friction factors, as well as good wear ability.
Effect of Adding Stone Sludge as Sand Replacement on Fresh Properties of Mortar
Authors: Xia Yong , Chen Jia Jian , Ma An Min , Li Zi Hong
Published: April 2020

Shortage of river sand and disposal of stone sludge are the problem of the construction and stone product industries, respectively. Utilization of stone sludge in mortar is one of the feasible strategies to solve these two problems. To study the effects of addition of stone sludge on the performance of mortar, 20 mixes of stone sludge powder mortar with various water/cement ratios and various stone sludge powder contents were produced for flowability measurement. To further study the governing mechanism of flowability and the packing densities of the solid proportions of the 20 mortar mixes were measured. Based on the packing density results, the average film thickness (AFT) of the 20 mortar mixes were calculated for flowability indication. Results proved that addition of stone sludge powder as sand replacement would decrease the flowability. The flowability was mainly governed by the AFT.
Experimental Study on Compressive Property of Basalt Fiber Reactive Powder Concrete
Authors: Wang Lu Liang , Zhao Hai Long , Wang De Hong , Bai Jun Feng
Published: April 2020

In order to study the stress-strain relationship of basalt fiber reactive powder concrete (RPC), the compressive stress-strain curve test of four groups of basalt fiber RPC was carried out. The test parameters including two kinds of basalt fiber length and three fiber volume fractions showed that the deformability of the test piece was improved and the failure process was delayed after incorporating basalt fiber. The optimum fiber fraction of the test piece with 12 mm long fiber was 0.10%. According to the experimental data, the stress-strain of the basalt fiber RPC was drawn. For the curve, the constitutive relation is fitted by the piecewise equation, and compared with the experimental curve, the fitting result is better.
Determination of Migration of 11 Organotin Compounds in Food Contact Materials by GCMS
Authors: Ye Guang Bao
Published: April 2020

The determination of the migration of 11 organotin compounds in food contact materials by GC-MS was established. The gastric acid was simulated with 0.07 mol/L hydrochloric acid solution, and the sample was soaked and extracted, and then derivatized with sodium tetraethylborate, extracted with n-hexane liquid solution, detected by GC-MS, and quantified by internal standard method. The linear range of the method is 5~600 μg/L, the correlation coefficient is greater than 0.997, and the method detection limit is 0.014 mg/kg. The recoveries of the three concentration levels ranged from 83.6% to 105.6% with a relative standard deviation of less than 11.4%. The method is simple and sensitive, and can be used for detecting the migration of organotin compounds in food contact materials.
Green Methods for Preparing Ag Nanoparticles Decorated Non-Woven Fabrics with High Antibacterial Efficiency
Authors: Jin Zhi , Ji Jin Ru , Wang Xi Ya , Shi Chao Fan , Zhang Xi Wen
Published: April 2020

The present study involves preparation of Ag nanoparticles (Ag NPs) deposited on non-woven fabrics by a two-step method including the chemical precipitation of Ag2O nanoparticles on the fabrics followed by in situ reducing of the precursor into Ag NPs by different reductive processes including chemical reduction, photo-reduction and dielectric barrier discharge (DBD) cold plasma treatment. The morphology as well as the antibacterial efficiency of the Ag NPs deposited on non-woven fabrics are also evaluated. The Ag NPs-modified fabrics prepared by DBD plasma treatment exhibit significant antibacterial properties against both Escherichia coli and Staphylococcus aureus, and accordingly have potential applications in the healthcare and medicine fields.
Irradiation Effect on Al-Dispersed Amorphous Silicon Thin Films by Femtosecond Laser
Authors: Liu Cheng , Song Yu Hao , Li Dong Yang , Li Wei
Published: April 2020

The structural and optical properties of amorphous silicon (a-Si) and Al-dispersed amorphous silicon (a-Si:Al) thin films irradiated by femtosecond (fs) laser at various energy densities are investigated comparatively in this article. It is found that there is an uneven crystallization in both amorphous thin films by means of optical microscopy and laser Raman spectroscopy respectively. The crystallization in each pulse spot area is gradually weakened from the center to the edge along with the energy dispersion of laser irradiation. The laser induced crystallization in a-Si thin films begins early and develops more extensively compared to that in a-Si:Al thin films, and Al nanoparticles inhibit somehow the crystallization of a-Si in a-Si:Al thin films.
Validation study on new isothermal container for hot ready to eat food in catering establishments: Preliminary results
Authors: Castrica Marta , Razzini Katia , Panseri Sara , Balzaretti Claudia M.
Published: April 2020

The production methods, in particular the cook-serve method, applied in high production catering establishments, even if inserted in a correct spatial design, it is affected by time-temperature flows characterized by inadequate designed moments during which critical points can be observed. The aim of this study was to evaluate, at a preliminary stage, how the new technologies can support the supply chain and production processes in catering establishments. To this end, a specific passive and active heat storage system was tested: “Polibox Smart Heater®” (PX SH), which makes an isothermal expanded polypropylene container an advanced maintainer for ready to eat food. The experimental design was divided into four different experiments, during which the functionality of the isothermal containers was evaluated, and thermal-tightness tests were carried out. The results showed that the PX SH containers, containing a heat accumulator, are temperature maintainers, which guarantee thermal stability (>65°C), according to the current standard (UNI EN 12571:1999). In conclusion, the production chain of catering establishments should use innovative technologies such as PX SH, in order to benefit from performance consistent with the safety, hygiene and sensory criteria.
Characterization of the temperature fluctuation effect on shelf life of an octopus semi-preserved product
Authors: Giarratana Filippo , Nalbone Luca , Ziino Graziella , Giuffrida Alessandro , Panebianco Felice
Published: April 2020

The aim of this work is to study the effect of temperature fluctuations on spoilage microbial flora behaviour of a semi-preserved seafood product in modified atmosphere packaging (MAP) as well as to find correct interpretation criteria for simulating temperature fluctuations during storage tests. The study concerned 54 packages of “Octopus carpaccio” that were grouped in three batches and stored at 3 different temperature profiles: the first (16 packages - Group 4°C) was stored at 4±0.5°C; the second (16 packages - Group 8°C) was stored at 8±0.5°C; the third (16 packages - Group F) was stored under a fluctuating temperature regime between 2°C and 14°C. Spoilage microflora, pH and AW has been monitored, at regular intervals, along the storage period (44 days). A predictive model was constructed according to the accredited scientific literature and validated against the observed growth curves of the above three groups. Afterwards, the predictive model has been used setting the temperature at the mean value of fluctuations (6.72°C), at the kinetic mean value of fluctuations (7.80°C) and at the 75th percentile value of fluctuations (11.14°C). The best fitting to the observed data was obtained with the kinetic mean temperature value and this result shows that this parameter can be proposed to reproduce the temperature fluctuation along the distribution and the domestic storage when a storage test has to be carried out.
MARGHERITA Dâ€™AUSTRIA MUSICA E IDENTITÃ€ DI UNA PRINCIPESSA DEL RINASCIMENTO
Authors: Borghetti Vincenzo
Published: April 2020

In this essay I concentrate on Margaret of Austriaâ€™s chansonnier, BrusBR 228, reflecting on the role of this manuscript in the construction and performance of Margaretâ€™s identity as a princely reader and as a ruler. Following the path opened by recent studies on this manuscript, I propose an analysis of the chansonnier as a music book, that is, as an object constructed through the interaction of different communicative codes, pondering some elements particularly interesting for my perspective, such as the initial pages. On the basis of this analysis, I advance new hypotheses on the uses and meanings of BrusBR 228, as well as, more in general, on Margaretâ€™s reading habits and their potential cultural meanings and ideological ends.
The orthopoedic management of myelomeningocoele
Authors: Handelsman J. E.
Published: April 2020

No abstract available.
Effects of accreditation on United States and Canadian veterinary college libraries in the nineteenth and twentieth centuries
Authors: Whitaker Susanne K. , Croft Vicki F.
Published: April 2020

Objective: The authors’ objective was to document the effects of evolving veterinary accreditation standards on the development of currently existing accredited US and Canadian veterinary school libraries in the late nineteenth and twentieth centuries.Methods: We gathered historical standards that major veterinary accreditation agencies developed with respect to libraries and library services. Historical background on college libraries, their facilities, services, and personnel via surveys, literature searches, and archival documents was also collected. We then correlated the evolving standards with each library’s development.Results: There was a marked correlation between the prevailing accreditation standards and library development, particularly during the post–World War II era and through the mid-1980s. These impacts—which included new and separate facilities, hiring of professional librarians, and additional open hours—affected not only the twenty new developing veterinary schools, but also the libraries of the preexisting colleges.Conclusions: Professional veterinary accrediting standards were an important influence on the evolution of veterinary school libraries, particularly during the years of major growth in the number of new veterinary colleges in the United States and Canada. In the 1990s and beyond, both libraries and accreditation standards continue to evolve in response to changes in technology, economics, publishing methods, and more. This latter is a story yet to be told.