bluuebunny/crossref_metadata_2025 huggingface dataset:
Ultrafiltration-based Extraction and LC-MS/MS Quantification of Phenylalanine in Human Blood Sample for Metabolite Target Analysis
Authors: Çelebier Mustafa , Reçber Tuba , Nemutlu Emirhan , Kır Sedef
Published: July 2019

Background:

Phenylalanine is a significant biomarker for various diseases like phenylketonuria,
gastric cancers, and ischemic stroke according to recent studies.

Methods:

In the present study; a simple, sensitive, selective and novel analytical method was validated
by using an ultrafiltration-based extraction and LC-MS/MS quantification of phenylalanine in human
plasma using 13C phenylalanine heavy isotope. Amicon® Ultra Centrifugal Filter was used for ultrafiltration.
Parameters affecting LC separation and MS/MS detection were investigated and optimized.
Chromatographic separation was achieved on a Merck SeQuant ZIC-HILIC (100x4.6 mm, 5 μm) at a
column temperature of 40°C using a mobile phase of mixture of acetonitrile containing 0.1% formic
acid and water containing 0.1% formic acid (50:50 v/v) at a flow rate of 0.35 mL/min. The transitions
m/z 167→121 for 13C phenylalanine, m/z 166→120 for phenylalanine itself were monitored using the
MRM mode.

Result:

The assay was linear concentration range of 0.0025 μg/mL to 1.20 μg/mL (R2=0.999). The developed
method was validated according to FDA guidelines. The method was found linear, sensitive,
precise, accurate, and selective.
Effect of Contamination, Damage and Barriers on the Light Output of Light-Curing Units
Authors: Suliman Abdulhaq A. , Abdo Ahmad A. , Elmasmari Hussein A.
Published: July 2019

Background:

Light-curing is a crucial step during the application of composite resin restorations. The clinical success of composite depends on the Light-Curing Units (LCU) to deliver adequate light energy to polymerize the resin. However, light-curing usually does not receive the proper awareness it deserves.

Objective:

This study aims to evaluate the effect of contamination and debris of the LCU’s tip on its light output. Determine the effect of damage to the LCU’s tip such as chipping, dents and scratches. Additionally, it evaluates the effect of plastic barrier sleeves.

Methods:

Sixty LED LCUs were tested using MARC™ Resin Calibrator (BlueLight Analytic Inc., Halifax, Canada) to measure their irradiance and energy before and after cleaning their tips. They were also tested with and without a clear plastic barrier. Additionally, four damaged LCUs received new tips and were tested again. Kruskal-Wallis H and One-Way ANOVA tests were used for statistical analysis.

Results:

Cleaning the LCUs’ tips showed significant improvement, an average increase of 8.2%. However, some units increased by up to 47% in irradiance and energy values. Replacing the damaged tip with a new one significantly improved the output of the LCUs, increasing light energy by up to 73%. The barrier used in this study caused 7% reduction in the energy delivered by the LCUs. The statistical analysis showed that cleaning the LCUs and replacing their damaged tips resulted in a significant increase in energy (p<0.05).

Conclusion:

Unclean or damaged LCUs’ tips can drastically reduce the light output of the LCUs, reducing the quality of the composite restorations. Clinicians are strongly recommended to regularly monitor, clean and maintain their curing lights.
Immunosuppressive Effect of Mesenchymal Stromal Cells is Enhanced by IL-1α from Oral Squamous Cell Carcinoma Cells
Authors: Morimoto-Ito Hiroe , Mizuno-Kamiya Masako , Umemura Naoki , Inagaki Yoshinori , Takayama Eiji , Kawaki Harumi , Muramatsu Yasunori , Sumitomo Shinichiro , Kondoh Nobuo
Published: July 2019

Background:

We have already reported that mouse Oral Squamous Carcinoma Cells (OSCCs) Sq-1979 specifically enhance the immunosuppressive activity of mesenchymal 10T1/2 cells via the functional soluble factor (s).

Objective:

In this report, we attempted to identify soluble factor(s) mediating the immunosuppression of Sq-1979 cells.

Methods:

L5-11 cells are a variant established from the metastatic lymph nodes of Sq-1979-implanted mice. Unlike parental Sq-1979 cells, however, L5-11 cells lack promotion of immunosuppressive activity in 10T1/2 cells. In order to identify cytokine mRNAs specifically expressed in Sq-1979 cells but not in L5-11 cells, cDNA microarray was performed. Conditioned medium from Sq-1979 cells (CM) was absorbed by several different neutralizing antibodies (abs) against the corresponding cytokines. The absorbed CM was then co-cultured with 10T1/2 cells and anti-CD3 antibody-stimulated mouse spleen cells. The Interferon (IFN) -γ producing capability of the stimulated spleen cells was evaluated using Enzyme-Linked Immunosorbent Assay (ELISA). By using a specific cytokine product instead of CM in this co-culture system the source of the immunosuppressive effect was identified.

Results:

The expression of Ccl2, Ccl7, Il1-α, IL1f6 and Il6 mRNAs was specifically elevated in Sq-1979 cells compared to L5-11 cells. The suppression of the IFN-γ producing capability of stimulated spleen cells in the co-culture system was specifically alleviated by absorbing the CM with anti-IL-1α ab. We further demonstrated that the immunosuppressive effect of CM in the co-culture system could be completely substituted by IL-1α protein (50 pmol/ ml).

Conclusion:

The immunosuppressive function of 10T1/2 cells is specifically promoted by IL-1α, secreted by Sq-1979 cells.
Dynamic Consolidation of Virtual Machine: A Survey of Challenges for Resource Optimization in Cloud Computing
Authors: Kani A.M. Serma , Paulraj D.
Published: July 2019

Background::

Virtualization is an efficient technology that accelerates available data center to
support efficient workload for the application. It completely based on guest operating system which keeps
track of infrastructure that keeps track of real time usage of hardware and utilization of software.

Objective::

To address the issues with Virtualization this paper analyzed various virtualization terminology
for treating best effective way to reduce IT expenses while boosting efficiency and deployment
for all levels of businesses.

Methods:

This paper discusses about the scenarios where various challenges met by Dynamic VM
consolidation. Dynamic conclusion of virtual machines has the ability to increase the consumption
of physical setup and focus on reducing power utilization with VM movement for stipulated period.
Gathering the needs of all VM working in the application, adjusting the Virtual machine and suitably
fit the virtual resource on a physical machine. Profiling and scheduling the virtual CPU to another
Physical resource. This can be increased by making live migration with regards to planned schedule
of virtual machine allotment.

Results::

The recent trends followed in comprehending dynamic VM consolidation is applicable either
in heuristic-based techniques which has further approaches based on static as well as adaptive
utilization threshold. SLA with unit of time with variant HOST adoption (SLATAH) which is dependent
on CPU utilization threshold with 100% for active host.

Conclusion::

The cloud provider decision upon choosing the virtual machine for their application also
varies with their decision support system that considers data storage and other parameters. It is
being compared for the continuous workload distribution as well as eventually compared with
changing demands of computation and in various optimization VM placement strategies.
The Effect of Proteinuria on Antinuclear Antibody Assay Results in Patients with Glomerulonephritis
Authors: Sarfaraz Sabahat , Anis Sabiha , Ahmed Ejaz , Muzaffar Rana
Published: July 2019

Background:

Glomerulonephritis mostly results from dysregulated immune system. Impaired immune mechanisms can be primary or secondary to an autoimmune disorder. Antinuclear antibodies (ANA) are hallmark of autoimmunity and are frequently present at high titer (≥ 1: 160). ANA are characterized via anti-double stranded deoxyribonucleic acid (dsDNA) and antiextractable nuclear antigen (ENA) antibodies for the identification of underlying autoimmune disease. Heavy proteinuria can affect assessment of autoantibodies hence special attention is required for the definitive diagnosis in such cases.

Objective:

Our aim was to determine impact of heavy proteinuria on ANA titer, anti-dsDNA and anti-ENA antibodies in glomerulonephritis patients.

Methods:

150 glomerulonephritis patients were enrolled in this study. All had antinuclear antibodies, samples were tested for anti-dsDNA and anti-ENA. ANA titer of ≥1:160 was taken significant. Proteinuria was assessed by spot protein/creatinine ratio. Data was analyzed using SPSS software version. 20

Results:

Heavy proteinuria was present in 119(79%) patients. Low ANA titer(≤1:80) was present in 37(25%) patients. Of 33 patients with heavy proteinuria and low ANA titer, ANA was characterized in 11 patients. These include anti-dsDNA(two), anti-SSA(four), anti-Sm (one), antihistones( one), anti-RNP(two), anti-Pm-Scl(one) and anti-ribosomal P protein (two).There was no significant difference in the prevalence of various autoantibodies in patients with high or low ANA titer with heavy proteinuria.

Conclusion:

This study highlights the importance of low ANA titer in glomerulonephritis patients in the setting of heavy proteinuria. Significant protein loss may alter actual titer of autoantibodies. Hence in this scenario clinically correlation along with ANA characterization via specific autoantibodies is required for adequate patient management.
Recent Advances in Preparation and Application of Functionalized Mesoporous Materials
Authors: Liu Jianghong , Wei Xiaohang , Yuan Dandan , Ren Jingwei , Xue Jian
Published: July 2019

Functionalized mesoporous materials are widely used in the environmental field
due to their excellent adsorption and catalytic properties. The materials with different functions
are obtained by modifying mesoporous materials. In this paper, the preparation methods
of functional mesoporous materials with functional groups, metal doping and acid modified
were presented. This review focused on the main features and applied prospects of functionalized
mesoporous materials under three producing methods. Recent advances of functionalized
mesoporous materials in the fields of adsorption and catalysis have been summarized.
Adsorption mainly refers to the treatment of heavy metals, organic contaminant, dyestuff
and CO2. Finally, the trends and application foreground of functionalized mesoporous
materials were elaborated in this paper, which provided reference and guidance for the development
of functional mesoporous materials.
Some Morphological and Functional Aspects of Chronic Osteomyelitis in Patients with Neurogenic Foot Deformities
Authors: Sudnitsyn A. S. , Shchurova E. N. , Varsegova T. N. , Stupina T. A. , Migalkin N. S.
Published: July 2019

Relevance. Neurological disorders are one the most frequent cause for developing of chronic foot inflammation. Analysis of pathological picture of chronic osteomyelitis in patients with neurogenic foot deformities, including cases of spina bifida, is not adequately addressed.Purpose of the study — to examine morpho-functional aspects of chronic osteomyelitis in patients with multicomponent foot deformities and with spina bifida.Materials and Methods. The present paper is based on the study of 30 patients with multicomponent neurological foot deformities complicated by chronic osteomyelitis who had medical history of spina bifida (myelomeningocele type). Histology was used to examine resected fragments of affected bone tissue, bone sequestration and skin adjacent to osteomyelitis area. Laser doppler flowmetry was used to study capillary cutaneous blood flow on plantar foot surface. Thermal and pain sensitivity was assessed by electric sensimeter in L4, L5, S1 dermatomas on the right and on the left sides.Results. Biopsy skin specimens harvested at osteomyelitis area demonstrated signs of parakeratosis, absence of stratum lucidum, epidermis acanthosis with 25% thickness increase (р = 0,04), 2,2 times increase of density for microvessels of the dermis (р = 0,73Е-4) and increased rate of capillary blood flow at 81,6±14,2% (р = 0,0004), fibrosis and dermis thinning at 19,1% (р = 0,03), 1,37 times increase in bulk density of perspiratory glands (р= 0,04), loss of adipose tissue and degeneration of nerve fibers in the majority of nerve stems of the dermis. Above factors were accompanied by disorders in thermal and pain sensitivity in 100% of cases and in 29% of those sensitivity was missing. Morphological picture of bone tissue in osteomyelitic area was manifested by multiple destruction cavities with pyogenic membrane, granular tissue of varying maturity, combined chronic and acute stages of the process, and by poor restorative bone formation.Conclusion. Disorders or lack of thermal and pain sensitivity in dermatomas L4, L5, S1, of safety sense and motion control, resulting chronic load on atypical foot segments, as well as patho-histological skin alterations contribute to ulcer formation and osteomyelitis in patients with spina bifida and multicomponent foot deformities. Morphological picture of foot bony tissue at osteomyelitic site indicates typical patho-morphological signs of chronic inflammation with poor restorative bone formation.
Changes in the Structure and Mechanical Properties of the Bone after Puncture Cryoablation: Experimental Study
Authors: Belyaev A. M. , Prokhorov G. G. , Sushnikov V. A. , Artemyeva A. S. , Arkhitskaya A. A. , Chuglova D. A.
Published: July 2019

Purpose of the study — to evaluate possible impact of cryoablation on a healthy bone and to identify probable causes of postoperative fractures.Materials and Methods. The authors performed cryoablation of the femur in the experiment on 8 mature rabbits of Soviet Chinchilla (SC) breed with a follow up for up to two months. Anitrogenous cryoprobe of 1.5 mm in diameter was introduced into the femur through a perforation hole. The bone was completely frozen up to -180°С in two cycles with continuous thermometry. Pathomorfological examinations were performed after 7 and 55 days along with assessment of bone hardness. Preparation of material stipulated sawing the bone at the fracture site along the bone axis. One half-bone was used for histological examination, and another one — for measuring mechanical properties by local pressing of a diamond indenter onto the bone at certain applied force. The distance between measurement points along the bone was 250 μm. Statistical processing included variance significance analysis using t-test.Results. The authors reported bone fractures at the site of cryodestruction in all animals in one week after the procedure. Statistical analysis of the measurements and histological examination demonstrated that freezing of the entire bone diameter up to -180°С results in its complete destruction. Strength reduction around the fracture site corresponded to the temperature distribution area in the range from -9ºС to -15ºС. However, areas of cooling below -40ºС exhibited some bone segments with normal hardness. Mosaic pattern of strength reduction is explained by microcirculation disorders. Histology confirmed thrombosis of intraosseous blood vessels in the area of cryotherapy. The first focal signs of osteomalacia emerged by the end of the first week after cryoablation. Subsequently, the bone preserved its regenerative properties, but by the end of the second month after the procedure the histogenesis was still not completed and the bone did not regain its strength.Conclusion. The authors believe that a limited number of cases, the specific features of the angioarchitecture of animal bones and their ability to produce a heavy periosteal response do not allow to apply obtained quantitative outcomes of the present study to clinical situations. However, complete freezing of the entire bone diameter inevitably results in fracture formation.
Metabolomic Study of Three Species in Zingiberaceae Family based on 1H-NMR
Authors: Wahyuni Dinar Sari Cahyaningrum , Kristanti Magdalena , Marliyana Soerya Dewi , Rinanto Yudi
Published: July 2019

Zingiberaceae is an economical plant and widely used as traditional medicines. Its rhizomes have been reported to have biological effects due to their metabolites content. However, metabolites profiling in Zingiberaceae has been little reported comprehensively. Therefore, this study aimed to profile primary and secondary metabolite of three species Zingiberaceae rhizomes (Zingiber amaricans BI, Zingiber officinale Roscoe, and Alpinia purpurata (Vieill.) K.Schum using 1H-NMR-based metabolomic approach. All samples were collected from local farmer located in Nguter, Sukoharjo, Central Java. Multivariate statistical analysis and ANOVA applied to measure the differences. It resulted that metabolite profiling discriminated between Zingiber and Alpinia samples. Fructose, α-glucose, β-glucose, sucrose, malic acid, alanine, valine, and shogaol contributed in discrimination between Z. amaricans BI, Z. officinale Roscoe, and A. purpurata (Vieill.) K.Schum. Sugar (α-glucose, β-glucose, fructose, and sucrose) and malic acid were significantly higher in Alpinia than in Zingiber samples. Relative concentration of amino acids (alanine and valine) and shogaol were significantly higher in Z. officinale. This result might be useful for databases and supplementary informations in Z. amaricans, Z. officinale, and A. purpurata taxonomy classifications.
EFL Teachers’ Awareness, Practices and Challenges of Teaching English Communicatively in Oman Post Basic Education Schools
Authors: Sawafi Amira Al , Humaidi Dr. Salma Al , Al Mekhlafi Dr. Abdo Mohamed
Published: July 2019

This study investigated the perceived knowledge and actual practice of Communicative Language Teaching (CLT) among post basic education teachers in Omani schools, along with the influence of gender and length of teaching experience years on teachers’ practice of this approach. It also explored the different challenges faced by teachers when implementing CLT. A total of 122 EFL Omani teachers took part in this study. The respondents completed the following: (1) a twenty-five item questionnaire concerning CLT principles; and (2) a questionnaire regarding the challenges of CLT. The results revealed that Omani EFL teachers have a high degree of awareness of the principles of CLT. However, they practice this approach at a moderate level, while their gender and length of teaching experiences have little impact on their actual practice of this approach. The findings further indicated that the implementation of CLT in Omani classrooms is hindered by: (1) teachers’ lack of training in CLT; (2) lack of time to prepare communicative activities; (3) students’ low levels of proficiency in English; (4) large class sizes; and (5) difficulties assessing the linguistic aspects of the language. This resulted in the drawing up of a number of recommendations.
ANTIBACTERIAL ACTIVITY OF BAWANG DAYAK (ELEUTHERINE SP.) AND TAWAS UT (AMPELOCISSUS SP.) FROM CENTRAL KALIMANTAN AGAINST PROPIONIBACTERIUM ACNES
Authors: ARDHANY SYAHRIDA DIAN
Published: July 2019

Objective: The aim of the present study was to investigate phytochemical screenings and the in vitro effect antibacterial of BD (Eleutherine Sp.) and TU (Ampelocissus Sp.) against Propionibacterium acnes.Methods: The antibacterial activity was investigated against Propionibacterium acnes by well diffusion method.Results: Preliminary phytochemical screenings of BD ethanolic extract were found positive alkaloid, saponin, tannins, and steroid while TUpositive flavonoid, saponin, tannins, steroid, and triterpenoid. Antibacterial activity against Propionibacterium acnes of ethanolic extract BD with concentration 25 mg/ml and 50 mg/ml showed the zone of inhibition 3.23 mm and 7.8 mm with category weak activity while ethanolic extract TU with same concentration showed zone of inhibition 10 mm (weak activity) and 16.3 mm (moderate activity) which mean ethanolic extract TU have better antibacterial activity. A combination ethanolic extract of both with variant ratio showed a zone of inhibition 6.7 mm (1:1), 3.9 mm (1:2), and 3.63 mm (2:1).Conclusion: In this present study showed the highest potential antibacterial activity against propionibacterium acnes is an ethanolic extract of TU and The best ratio combination is 1:1. Furthermore, this study needs more research with variant concentration so that may be possible to be used as natural anti-acne formulations.
Observing and drawing the Sun: research-based insights to assess science communication practices aimed at children
Authors: Anjos Sara , Aibeo Alexandre , Carvalho Anabela
Published: July 2019

Knowing how specific publics understand and experience science is crucial for both researchers and practitioners. As learning and meaning-making develop over time, depending on a combination of factors, creative possibilities to analyze those processes are needed to improve evaluation of science communication practices. We examine how first grade children's drawings expressed their perceptions of the Sun and explore their views of a major astronomical body within their social, cultural and personal worlds. We then examine how the observation of the Sun through a telescope led to changes in graphical representations, and how learning and meaning evolved after several months.
IMPROVEMENT BONDING QUALITY OF SHOE USING QUALITY CONTROL CIRCLE
Authors: Beatrix Meike Elsye , Triana Novera Elisa
Published: July 2019

Shoe industry development in the era of globalization is currently overgrowing. Therefore, every company should be able to compete strictly with other companies that produce the same products. Quality maintenance is having to be done by the company to survive in business competition. PT. ABC is a manufacturer of sports shoes. The company has a problem with bonding shoes not achieved company standard in the year 2017. This paper is focused on the improvement of bonding shoe quality by using a method of Quality Control Circle which applying quality control tools are like check sheet, Pareto diagram, fishbone diagram, and 5W + 1 H. Based on the research results obtained percentage improvements of quality bonding test of 21.15%. Cement stripping on the midsole is the most significant number of the bonding test failure in Laboratory that is as much as 26.33% or 218 prs from the total collapse of the overall bonding shoes. Based on the background, the purpose of this research is to find out the root causes of the failure of bonding test shoes. The limitations of this research are only improving processes in the department, which makes the bonding shoe quality does not achieve the company standard. After doing the analysis using the quality control tools and making the improvement process in the whole areas that the percentage of the bonding test cement stripping on midsole could be increased to 5.18%. Analysis of the results obtained by applying the method of Quality Control Circle is the improvement of the quality of the bonding shoe. So, the trust customers against the company may be obtained that would eventually increase the number of orders to the company.
PERCEPTION OF NEIGHBORHOOD AROUND THE REAL ESTATE PHYSICAL BOUNDARY
Authors: Utami Tin Budi
Published: July 2019

The presence of real estate in South Tangerang cannot be separated from a surrounding settlement or new settlements that grew later. Regulation and design are more set-in real estate planning so that real estate tends to form an enclave for security and social image. Forming some type of physical boundary with surrounding residential of real estate perceived vary both by residents and outside the real estate. This study aims to map out how the perception of the surrounding community to the physical boundaries of real estate on a cluster pattern made by the developer, with research sites in Bintaro Jaya, South Tangerang. The method used observation and structured interviews with communities. The surrounding community has very positively responded to the presence of real estate, but the relationship with the institution is perceived as not useful because of the boundary design is more detrimental for them. Their participation in the plan has not been well accommodated so that access is closed unilaterally by the developer.The presence of real estate in South Tangerang cannot be separate from a surrounding settlement or new settlements that grew later. Regulation and design are more set-in real estate planning so that real estate tends to form an enclave for security and social image. Forming some physical boundary with surrounding residential of real estate perceived vary both by residents and outside the real estate. This study aims to map out how the perception of the surrounding community to the physical boundaries of real estate on a cluster pattern made by the developer, with research sites in Bintaro Jaya, South Tangerang. The method used observation and structured interviews with communities.The surrounding community has very positively responded to the presence of real estate, but the relationship with the institution is perceived as not useful because the boundary design is more detrimental for them. Their participation in the plan has not been well accommodated so that access is closed unilaterally by the developer.
Influence of different functionalization methods of multi-walled carbon nanotubes on the properties of poly(L-lactide) based nanocomposites
Authors: Vukic Nevena , Ristic Ivan , Marinovic-Cincovic Milena , Radicevic Radmila , Pilic Branka , Cakic Suzana , Budinski-Simendic Jaroslava
Published: July 2019

This paper presents influence of the type of carbon nanotube
functionalization on properties of poly(L-lactide) (PLLA) based
nanocomposite materials. For this purpose surface modifications of
multi-walled carbon nanotubes (MWCNTs) were performed by chemical and
irradiation techniques, while thermo gravimetric analysis, UV-Visible and
Fourier-transform infrared (FT-IR) spectroscopies confirmed successful
covalent functionalization. Series of PLLA bionanocom-posites with different
contents of functionalized MWCNTs (0.7; 1.6; 2.1 wt%), were synthesized via
ring-opening solution polymerisation of L-lactide. FT-IR analysis confirmed
that grafting of L-lactide, under controlled condition, is possible to
perform starting from the surface of functionalized MWCNTs. From
differential scanning calorimetry results it was concluded that even low
contents of chemically and irradiation functionalized MWCNTs had a
significant effect on thermal properties of the prepared nanocomposites,
raising the values of melting and glass transition temperatures.
Thermogravimetric analysis (TGA) has shown that the degradation onset
temperature for composites with chemically functionalized MWCNTs, was much
higher than that for the neat poly(L-lactide) sample and composites with
irradiation functionalized MWCNTs. Morphology studies by scanning electron
microscopy (SEM) and transmission electron microscopy (TEM) indicated that
poly(L-lactide) covered surfaces and separated functionalized MWCNTs. Good
dispersion of carbon nanotubes in polymer matrix enabled conductivity of
synthesized materials, as determined by conductivity tests.
PENCAPAIAN KRITERIA KETUNTASAN MINIMAL DALAM PEMBELAJARAN SOSIOLOGI DI SMA KOTA PADANG
Authors: Muammar Muammar
Published: July 2019

Artikel ini membahas tentang strategi pencapaian KKM dalam pembelajaran Sosiologi di SMA Kota Padang. KKM pada mata pelajaran Sosiologi yang ditetapkan di SMA Kota Padang tergolong tinggi, sedangkan dari segi ketercapaian rendah. Namun guru tetap mengusahakan nilai peserta didik mencapai KKM yang telah ditetapkan di sekolah. Dalam hal ini guru sebagai perencana dan imlementator memiliki strategi pencapaian yang berbeda-beda dalam pencapaian KKM. Strategi pencapaian KKM pada pembelajaran Sosiologi ditinjau dari proses pembelajaran, ketersediaan sumber belajar dan proses penilaian. Oleh karena itu, penelitian ini dianalisis dengan menggunakan teori struktural fungsional Talcoth Parsons yang dikenal dengan skema AGIL. Penelitian ini merupakan penelitian dengan pendekatan kualitatif deskriptif. Pemilihan informan dilakukan dengan pemilihan teknik purposive sampling dengan jumlah informan 29 orang. Pengumpulan data dilakukan dengan observasi, wawancara mendalam dan studi dokumentasi. Data yang telah terkumpul dilakukan triangulasi sumber dan dianalisis dengan mengacu pada model analisi Miles dan Huberman. Hasil penelitian ini menunjukkan bahwa strategi yang dilakukan dalam mencapai KKM dalam pembelajaran Sosiologi adalah pertama, guru memvisualisasikan model, metode dan media pembelajaran yang bervariasi untuk meningkatkan pemahaman peserta didik. Kedua, memfasilitas sumber belajar, dan menyediakan fasilitas yang mendukung proses pelaksanaan proses pembelajaran Sosiologi seperti proyektor, tv dan komputer. Ketiga, melakukan proses penilaian yang otentik, dimana guru melakukan penilaian sikap, pengetahuan, dan keterampilan. Dalam hal ini guru dan pihak sekolah menerapkan formula yang berbeda-beda agar tercapai KKM yang telah ditetapkan.
PENERAPAN MODEL PEMBELAJARAN TUTOR TEMAN SEBAYA DI SMAN 1 PASAMAN
Authors: Nurlizawati Nurlizawati
Published: July 2019

Penelitian ini bertujuan untuk mengimplementasikan pembelajaran lesson study dengan memfasilitasi tumbuhnya komunitas belajar melalui tutor teman sebaya pada mata pelajaran sosiologi di SMA Negeri 1 Pasaman Barat. Penelitian ini merupakan penelitian tindakan kelas (PTK), yang bertujuan untuk meningkatkan kemampuan kolaboratif (colaboration) dan komunikatif (communication) siswa sebagai aspek 4C yang harus dikembangkan pada peserta didik di abad 21. Penelitian ini akan dilaksanakan di kelas XI IPS SMA Negeri 1 Pasaman Barat. Hasil Penelitian yang diharapkan adalah pertama pada aspek kognitif siswa dapat lebih mudah memahami materi karena melalui tutor teman sebaya akan terbangun perilaku potensial melalui pengorganisasian materi pembelajaran secara mandiri dalam bentuk mencari pertolongan dan memberi pertolongan selama proses belajar secara lebih intensif karena jarak psikologis yang minimal antara tutor dan tutee. Kedua, pada aspek afektif akan terjadi hubungan interaksi yang lebih erat antara peserta didik dan guru. Ketiga, Pada aspek keterampilan diharapkan akan terjadi peningkatan kemampuan kolaboratif dan komunikatif peserta didik. Pada akhirnya diharapkan pelaksanaan lesson study selama penelitian, juga telah mempererat kolegalitas antara tim peneliti dan guru mitra, membentuk mutual learning (saling belajar), terbentuknya komunitas belajar dan meningkatkan profesional guru sebagai pendidik dan pengajar
Application of Indigenous AMF from ex-coal Mining Soil Combined with Phosphorus Fertilizers to Improved Oil Palm Seedling Growth (Elaeis guineensis Jacq.)
Authors: Duaja Made Deviani , Kartika Elis , Lizawati Lizawati
Published: July 2019

Opencast mining caused heavy deforestation and barren land in Jambi. This ex-mining land must be reclaimed by planting crops based on biofertilizers containing mycorrhizae, this is a potential alternative that provides benefit both agronomy plant and ecosystem specially replanting with oil palm. Those are the technology for reclamation ex-coal mining soil. This research aim is to examine the effect of four combinations indigenous isolate of Arbuscular Mycorrhizae Fungi (AMF), which is originated from ex-coal mining soil that combined with Phosphorous fertilizers to minimize utilizing P fertilizer at oil palm pre-nursery, to improve soil fertility, and seedling growth. Hence, this research was arranged in factorial experiment with 2 factors, using a complete randomized design with three replications. The first factor is five different mycorrhizae isolates, representing a broad range of endomycorrhizae fungi, there are: without indigenous AMF, isolate of Glomus sp. 3, isolates of Glomus sp. 6, isolates of Glomus sp. 15 and isolates of Glomus sp. 16. The second factor is P fertilizer: control (without P fertilizers), fertilizer dosage P 25%, 50%, 75%, and 100%. Variables measured are shoot height, number of leaves per plant, total leaf area per plant, and plant stem diameter. The data were analyzed by analysis of variance to see whether there was an interaction between the MVA isolate and the P fertilizer dosage. The result showed a significant effect on palm oil seedling growth, shoot height, number of leaves per plant, total leaf area per plant but there is no interaction on the stem diameter. Plants that are inoculated with mycorrhizae have greater P content in leaves than those not inoculated. The types of isolated Glomus sp.3 and dosage P 75% of recommended dosage, give the best seedling growth. This research concluded that inoculation with AMF could minimize P fertilizers doses.
VULNERABILITY OF ELDERLY IN THEIR HOME ENVIRONMENT AT HIGH DENSELY SETTLEMENT
Authors: Pramitasari Diananta , Sarwadi Ahmad
Published: July 2019

Abstract_ This study basically aims to examine the vulnerability of the elderly when they are using the space in their home within a high densely settlement. Due to the high density of the urban settlement, the condition of the elderly living unit that located in the middle of settlement area is questioned. Under the condition of lack of space, actually two questions are appeared. First question is “how do the elderly residents use the space for their daily life?”. Moreover, the second question is about “is the room as well the home environment good enough for supporting the elderly daily activities and maintaining their health?” These questions are actually directing to necessary of examining the vulnerability the elderly in their own home. This study was carried out through conducting field observation and doing the individual interview in two neighborhoods located at the city center of Yogyakarta City. By interviewing the elderly residents this study identified the room or spaces that most frequently used the senior residents during their lives inside their own home. The identification then proceeds in to the assessment of the space condition especially related to the natural lighting and ventilation. This study found that in urban settlement with high density and aging population, there was subtle vulnerability existed in the spaces within the elderly’s home that most frequently used. This vulnerability was sourced at the conditions of natural lighting and fresh air ventilation that performed by the home environment properties. These physical aspects of the space considered significant since the resident houses were in very limited urban spaces. Although the vulnerability is subtle or slight, this condition indicates that the elderly residents’ health is really threatened.Keywords: Elderly; Home Environment; High Densely Settlement; Use of Space; Vulnerability.
Designed of Automatic Egg Incubator Based on Atmega328p Microcontroller
Authors: Fauzi Fauzi
Published: July 2019

Telah berhasil dilakukan sebuah perancangan ruangan penetas telur otomatis dengan memanfaatkan sensor DHT-11 yang berbasis mikrokontroler ATMega328p. Sistem ini dirancang sehingga suhu dan kelembaban ruangan pentetas tersebut dapat diatur secara otomatis. Otomatisasi pengontrolan sistem ini cukup kompleks dan membutuhkan berbagai komponen terintegrasi dengan kemampuan pembacaan masukan, pemrosesan data dan pengontrolan keluaran secara bersamaan dan terprogram. Sistem ini nantinya akan diaplikasikan untuk keperluan industri peternakan unggas. Penelitian ini berguna bagi peternak untuk melakukan proses pengontrolan penetasan dimana suhu dan kelembaban ruangan penetas secara otomatis akan diatur suhu dan kelembaban dengan sendirinya sehingga memudahkan peternak sebab tidak memerlukan pengamatan khusus terhadap suhu ruang dan kelembabannya. Sistem utama pada mesin penetas telur otomatis ini adalah sensor DHT-11 untuk mendapatkan nilai suhu dan kelembabannya dan data dari sensor tersebut akan diproses oleh sebuah mikrokontroler lalu ditampilkan nilainya pada LCD. Ketika suhu terlalu tinggi, maka kipas akan menyala dan lampu akan mati, sedangkan jika suhu lebih rendah dari set point maka lampu menyala kembali dan kipas akan mati. An automatic egg hatching room has been successfully designed by using the DHT-11 sensor based on the ATMega328p microcontroller. The system is designed so that the temperature and humidity of the plant room can be adjusted automatically. Automation of controlling this system is quite complex and requires various integrated components with the ability to read input, data processing and controlling output simultaneously and programmed. The system will later be applied to the needs of the poultry farming industry. This research is useful for farmers to carry out the hatching control process where the temperature and humidity of the incubator will automatically be regulated by temperature and humidity by itself so as to make it easier for farmers because it does not require special observations on the room temperature and humidity. The main system in this automatic egg incubator is the DHT-11 sensor to get the value of temperature and humidity and the data from the sensor will be processed by a microcontroller and displayed on the LCD. When the temperature is too high, the fan will turn on and the light will turn off, whereas if the temperature is lower than the set point, the light will turn on again and the fan will turn off. Keywords: ATMega328p, Sensor suhu, Adruino Uno, PentetasTelur.
Participatory budgeting in Portugal: development prospects
Authors: Gavrilova N. V.
Published: July 2019

Introduction. The relevance of the study is caused by the spread of participatory budgeting practices in Russia and abroad. In 2017 the joint project ‘Development of initiative budgeting in the Russian Federation’ of the Ministry of Finance of the Russian Federation and the World Bank has been launched. More than 50 Russian regions are involved in this project today. In March 2018 the need to develop citizen engagement was reflected in state program of the Russian Finance Ministry ‘Public Finance Management and Regulation of Financial Markets’. Since citizen participation in the budget process is still new, scholars and practitioners take interest in foreign experience, in particular, in the mechanisms used in European countries. Portugal is of a particular interest because the only nationwide practice of participatory budgeting is being implemented there.

Materials and methods. The article is based on the comparative historical analysis and case-study method. Academic articles, thematic books and monographs, official websites of the state and local authorities of Portugal, specialized online-participation portals, reports of foreign experts at the Moscow Financial Forum 2018 were involved as sources. The author also relied on oral information received from the representatives of the Branding and Communication Department of Lisbon during an in-person meeting at the City Hall in June, 2018.

Results. The historical and political context of the development of modern mechanisms of direct democracy in Portugal was identified. The nationwide program, national programs of school and youth participatory budgeting are analyzed. The specificity of the projects, the target audience and the results within each of the directions are described. Special attention is paid to the city of Lisbon, in which several crowdsourcing and participatory practices are implemented.

Discussion and conclusions. The most original approaches that are interesting from the point of view of the procedures used for engaging citizens or specifics of local issues that are presented for discussion in the framework of participatory practices are identified.
PENGARUH KEPEMIMPINAN, HUBUNGAN KERJA DAN LINGKUNGAN KERJA FISIK TERHADAP DISIPLIN KERJA KARYAWAN
Authors: Sugiantara I Wayan , Ardana I Komang
Published: July 2019

Business competition in the field of tourism accommodation causes corporate leaders and employees, especially lodging places, are required to always act professionally. The purpose of this study are (1) to determine the leadership style, work relationship and physical work environment simultaneously have a significant effect on employee work discipline, (2) to know the leadership style, work relationship and physical work environment partially have a significant effect on employee work discipline , (3) to find out the leadership style, work relationship and physical work environment dominantly have a significant influence on employee work discipline. This research was conducted in Alam Kulkul Boutique Resort Kuta-Bali which is engaged in tourism accommodation using census method (total sampling) in determining a sample of 65 respondents, through multiple linear regression analysis techniques. The results of the analysis prove that leadership, work relationships and physical work environment simultaneously have a positive and significant effect on employee work discipline. Leadership, work relations and physical work environment partially have a positive and significant effect on employee work discipline. The work environment has a dominant and significant positive effect on employee work discipline.

Keywords: leadership, work relationships, physical work environment and work discipline
ANALISIS POTENSI EKONOMI KABUPATEN KARANGASEM DAN BANGLI
Authors: Utami Ni Kadek Sri , Abundanti Nyoman
Published: July 2019

The purpose of this study is to find out the leading sectors and sectors that have the potential to be developed in Karangasem and Bangli Regencies. This research is descriptive quantitative research conducted in Karangasem and Bangli Regencies using Regency GRDP data for 2015-2017. The analysis technique used in this study is the Overlay analysis and the Klassen Typology. Based on the analysis of the potential of the area with the Overlay analysis and the Klassen Typology, the leading economic sectors in Karangasm Regency consist of the construction, transportation and warehousing sectors, as well as providing accommodation and drinking meals, while in Bangli Regency consists of the processing, construction and large trade industries and retail; car and motorcycle repair. Sectors that have the same potential to be developed in Karangasem and Bangli Regencies are economic sectors that fall into the category of potential, developing, and underdeveloped.

Keywords: regional potential, overlay, classification typology
MODERN TECHNOLOGIES AND DIAGNOSTICS IN TREATMENT OF NEUROENDOCRINE TUMORS OF THE PANCREAS
Authors: Maistrenko N. A. , Romashchenko P. N. , Lysanyuk M. V.
Published: July 2019

The article presents the results of investigation and treatment of 124 patients with neuroendocrine tumors of the pancreas (NET P): insulinima (68 cases), gastrinoma (43 cases), rare forms of tumor (13 patients). It was stated that clinical manifestations of NET P resembled the signs of neurological and gastroenterological diseases. Thus, the terms of detection would be prolonged during pre-admission stage and this validated the reasonability of well-timed application of current laboratory methods of diagnostics. An appropriate clinic neuroendocrine syndrome could be confirmed in 93-96% of patients. The authors showed that available diagnostic technique of NET P were the helical computer tomography and endoscopic ultrasound study with sensitivity 75% and 91%, respectively. It was rational to complete study with the data of intraoperative sonography for final tumor localization and its assessment in relation to the connection with pancreas duct and vessels. At the same time, it could be used in case of suspicion to multiple neoplasia. Angiography in combination with arterial-stimulated blood sampling from the hepatic vein and positron emission tomography with 18-fluorodeoxyglucose were the additional methods of diagnostics concerning the main forms of limited hyperinsulinism and generalized forms of NET P. Immunohistochemical study of removed pancreas tumor was the main method of morphological verification of the diagnosis and it’s used to develop the further strategy of postoperative treatment for patients. The surgical method of treatment of patients with NET P allowed elimination of clinical laboratory manifestations of neuroendocrine syndrome and getting general cumulative 5-year survival (69,3±4,7%) of radically operated patients.
VALUE OF ANATOMICAL INTRACRANIAL RESERVE IN SURGICAL TREATMENT OF INJURIES AND DISEASES OF THE BRAIN
Authors: Shchedrenok V. V. , Moguchaya O. V. , Potemkina E. G. , Zakhmatov G. .. , Kotov M. A. , Sebelev K. I.
Published: July 2019

The authors proposed to evaluate the quantity of anatomical intracranial reserve according to morphometric measurements in axial projection by means of helical computer tomography data of bitemporal distance, width of the tentorial opening, diameter of the foramen magnum and mutual correlation of these parameters in points. This method showed a high accuracy (92%) and predictive value (85%) in determination of terms and volume of complex treatment of 140 victims with craniocerebral injury, 120 patients with primary tumors of the brain and 110 patients with acute disorder of cerebral circulation.
TREATMENT OF COLORECTAL CANCER COMPLICATED BY INTESTINAL OBSTRUCTION USING THE METHOD OF «FAST-TRACK» RECOVERY
Authors: Denisenko V. L. , Gain Yu. M.
Published: July 2019

A medical trend which is currently gaining strength includes the complex treatment based on the concept of «fast-track» recovery in oncology. An application of modern high-tech approaches allowed minimizing the terms of treatment, shortening economic costs and getting the highest final results. It provides a high quality treatment. Given method could exclude an interim treatment stages, sufficiently reduces terms of general treatment and rehabilitation of patients and could succeed in high quality of life for the patients in short- and long-term period. The authors present the results of successful clinical surgery of 78 patients using this method in public health.
SIDE-TO-END ANASTOMOSIS IN LOW ANTERIOR RECTAL RESECTION
Authors: Shelygin Yu. A. , Budtuev A. S. , Pikunov D. Yu. , Rybakov E. G. , Fomenko O. Yu. , Sevost’Yanov S. I.
Published: July 2019

The authors have launched a prospective randomized study aimed to make a comparison of functional results of formation of straight coloanal (control group) and side-to end (main group) anastomosis in case of low anterior rectal resection since 2012. Each group consisted of 40 patients undergoing operation concerning uncomplicated rectal cancer of medium-ampullar section of rectum. It was noted that patients of the main group had lower stool frequency in postoperative period. A function of the interior sphincter was less damaged and the rate of compliance of rectum was high.
REMOTE 3-YEAR RESULTS OF APPLICATION OF «INDIRECT» WAYS OF REVASCULARIZATION IN PATIENTS WITH CHRONIC ISCHEMIA OF LOWER EXTREMITIES
Authors: Chervyakov Yu. V. , Staroverov I. N. , Borisov A. V. , Nersesyan E. G. , Vlasenko O. N. , Lavlinskiy S. N.
Published: July 2019

There are several ways of «indirect» revascularization such as revascularizated osteotrepanation of shinbone and lumbar sympathectomy (LS) for treatment of patients with chronic ischemia of lower extremities. They appeared to be sufficiently effective for the patients with II stage of the disease. Patients with critical ischemia (III stage) had persistent positive results after lumbar sympathectomy during 3-year period only in 33% of cases and using revacularized osteotrepnation - 46%. The difference in efficacy of treatment using LS and standard conservative therapy is statistically low significant, so that isn’t allowed recommending the sympathectomy for treatment of III stage ischemia. The method of revascularizated osteotrepanation of shinbone showed a reliably better result, therefore this way is reasonable to apply in surgery in case of III stage ischemia.