bluuebunny/crossref_metadata_2025 huggingface dataset:
Radix entomolaris – A case report
Authors: Felipe Davini  , Rodrigo Sanches Cunha  , Carlos Eduardo Fontana  , Claudia Fernandes de Magalhães Silveira  , Carlos Eduardo da Silveira Bueno
Published: August 2022

A comprehensive knowledge on the root canal anatomy is a basic prerequisite for the endodontic treatment successful. Mandibular molars may have an additional root located lingually (radix entomolaris) or buccally (radix paramolaris). In the literature, this anatomy variation is considered rare in Caucasian populations. Awareness and understanding of the presence of unusual external and internal root canal morphology contributes to the successful outcome of the root canal treatment.Objective and case report: The purpose of this study was to report a clinical case of successful endodontic treatment in a mandibular molar with pulp necrosis and characterized as radix entomolaris in which the use of magnification and ultrasonic tips (the “microsonics concept”) was fundamental to the management of the variations in the internal anatomy. Conclusion: A better understanding of the root canal morphology is essential for endodontic treatment success, as well as the use of technologic advancements in Endodontics including computed tomography, ultrasonic tips and the operating microscope.
Effect of staining agents on color change of composites
Authors: Mateus Rodrigues Tonetto  , Carolina Santezi Neto  , Cristina Magnani Felício  , Patrícia Aleixo dos Santos Domingos  , Edson Alves de Campos  , Marcelo Ferrarezi de Andrade
Published: August 2022

Composite resins are materials that can present color changing when exposed to pigments. Objective: The aim of this study was to evaluate, in vitro, the color changing of composites after immersion in different substances for different periods. Material and methods: Two microhybrid composite resins: Charisma (Heraeus – Kulzer) and Opallis (FGM) were used. Red wine and acai pulp were also used as immersion medium. For this study, 32 specimens with 10 mm of diameter and 2 mm of thickness were used, divided into 4 groups: Group 1 – Opallis composite immersed in red wine solution; Group 2 – Opallis composite immersed in acai berry pulp solution; Group 3 – Charisma composite immersed in red wine solution; Group 4 – Charisma composite immersed in acai berry pulp solution. The specimens were evaluated in the following time periods: T0 – baseline, T1 – 24 hours, T2 – 48 hours, T3 – 72 hours and T4 – 96 hours. For the assessment of staining, a spectrophotometer for colorimetry was used (Color Guide 45 / 0, PCB 6807 BYK-Gardner Gerestsried GmBH, Germany), and the values obtained were transferred to a computer and recorded according to CIELAB system. Results: The data were evaluated using Kruskal-Wallis non-parametric tests with the following ���ΔE mean values for � �the immersion periods of 24, 48, 72 and 96 hours, respectively: G1 – 7.35, 7.84, 9.04,10.48; G2 – 2.92, 4.15, 4.30, 4.64; G3 – 3.14, 7.35, 8.13, 8.43, G4 – 4.49, 5.99, 6.92, 6.76. Conclusion: Red wine showed a higher tendency toward altering the composite color than acai berry pulp. In addition, no significant difference was found concerning to the behavior of the two composite resins. Concerning to the immersion time periods, significant differences were only observed among the groups in the 24 hour time period.
Self-medication in health students from two Brazilian universities
Authors: Cláudio Maranhão Pereira  , Vírginia Farias Alves  , Patricia Freire Gasparetto  , Danilo Santos Carneiro  , Delprina de G. Rocha de Carvalho  , Felipe Eduardo Ferreira Valoz
Published: August 2022

Self medication is a component of self care and it is considered as primary public health resource in health care system. It can be defined as use of non-prescription medicines by people on their own initiative. Dentists, together with doctors and veterinarians, comprise the professional classes that may and must prescribe medications for their patients. On the other hand, the nursing professionals are the ones who more administer drugs to patients in the ambulatory and hospital. Objective: This study was aimed to find out the frequency of self medication in selected university students, to find out the difference in the proportions of self medication between dentistry and nursing students, as well to evaluate the students’ knowledge of harmful effects of self medication and common problems of students that use the self medication. Material and methods: We were applied 209 questionnaires among dentistry students from the 3rd to 8th semesters at the Paulista University/Goiânia and 542 among nursing students from the 3rd to 8th semesters at the Estacio de Sa University of Goiás. Results and conclusion: In the present study was observed a high rate of self-medication among undergraduate students in the health area, particularly among the dentistry and nurse students. The result was alarming because the professional him/herself who should educate patients and dissuade them from this practice is a habitual user; it makes it more difficult to aspire to the future inhibition and reduction of this practice that is so harmful to health.
Dental esthetic self-perception of Brazilian dental students
Authors: Gabrielle de Carli da Silva  , Eduardo Dickie de Castilhos  , Alexandre Severo Masotti  , Sinval Adalberto Rodrigues-Junior
Published: August 2022

Esthetics in dentistry aims to improve the patients’ self-esteem and satisfaction regarding how beautiful and attractive they feel. However, patients and dental professionals may perceive the concept of esthetics differently instead, which may cause the dissatisfaction of the patient with the results of the treatment. Objective: This cross-sectional observational study aimed to verify the esthetic self-perception of undergraduate dental students regarding their own smile. Material and methods: A questionnaire, designed by Goldstein [10] to measure the patients’ self-perception and satisfaction, regarding their smiles, was applied to undergraduate students of different semesters of the School of Dentistry of the Federal University of Pelotas. Results: Our results showed that women are more dissatisfied with their smiles than men. Students attending different semesters worried somehow about the esthetics of their smiles and revealed the wish of having whiter teeth. Most students are satisfied with the shape of their teeth. Ninety two percent of the students feel self-confident regarding to smile, 90% believe someone else has a better smile, 87% look at the smile of models in fashion magazines, 71% wish to have whiter teeth and 80% wish to have rather a bigger or smaller teeth. Conclusion: Undergraduate dental students have a positive self-perception of their smile. Women are less satisfied than men. Students of the earlier semesters wish to have whiter teeth than students from the later semesters.
Survey on jaw fractures occurring due to domestic violence against women
Authors: Thiago Serafim Cesa  , Regiane Benez Bixofis  , Jean Carlos Della Giustina  , José Luis Dissenha  , Maria Isabela Guebur  , Glória A. L. Huber  , Laurindo Moacir Sassi
Published: August 2022

Violence against women has become a public health problem, and the dentist is the main responsible for the treatment of their victims, since numerous cases with a high incidence of impaired maxillomandibular complex occurred. Objective: The aim of this study was to analyze the prevalence and evolution of jaw fractures in woman due to domestic violence. Material and methods: The medical files from the Hospital and Maternity of São José dos Pinhais/PR (HMSJP) was searched for female patients diagnosed with jaw fractures caused by trauma, considering the aggressor and the prevalence in the period from January 2001 to May 2003. Results: There were 23 women with jaw fractures, aged from 15 to 43 years. Nasal fractures were the most prevalent, followed by the zygomatic complex and mandible fractures. The husbands were the main responsible for the attacks. The fractures treated by reduction had satisfactory bone consolidation. Conclusion: Patients with jaw fractures had favorable bone consolidation after being submitted to surgical treatment. Nasal fractures were the most prevalent type and the husband was most responsible for the attacks.
Comparative study among Dentistry undergraduates and Forensic Odontology postgraduate students through smile photographs for human identification
Authors: Rhonan Ferreira da Silva  , Laíse Nascimento Correa Lima  , Leandro Brambilla Martorell  , Mauro Machado do Prado  , Luiz Francesquini Júnior  , Eduardo Daruge Júnior
Published: August 2022

The execution of forensic odontology technique for human identification depends on the existence of dental files produced ante-mortem (dental records, clinical notes, radiographs or dental casts). However, when these are not present, other sources of dental data should be searched, such as photographs of the smile. Objective:To compare the performance of undergraduates of Dentistry and postgraduate students of Forensic Odontology to execute human identification through the analysis of photographs of the smile based on decisive dental parameters. Material and methods: Forty Dentistry undergraduates of a School of Dentistry (20 presenting history of orthodontic treatment and 20 without treatment were photographed as follows: 1) extraoral photograph of posed smile, at frontal position and; 2) intraoral photograph, at frontal position. Using these 40 pairs of photographs, four tests were prepared (A, B, C and D) which were sent to both 12 undergraduates of Dentistry and 12 postgraduate students of Forensic Odontology both from another
Single-cone obturation technique: a literature review
Authors: Andréa Cardoso Pereira  , Celso Kenji Nishiyama  , Lidiane de Castro Pinto
Published: August 2022

The technique of single-cone obturation is a technique that uses only the master cone. There have been an increase in its use, especially by employing larger cones with larger taper sizes that best match the geometry of rotary nickel-titanium systems (NiTi), not requiring the use of accessory cones, thus reducing the time spent in endodontic obturation. Objective: To review the literature on this technique and to compare it with other existing techniques, as well as to elucidate its advantages and disadvantages. Literature review: The single-cone obturation technique enables an easier and faster endodontic obturation. However, regarding to the aspects such as the obturation quality, apical microleakage and bacterial penetration, this technique is similar to or lower than others. Conclusion: This technique has the advantage of saving time during the filling of the root canal. However, further studies are necessary to evaluate its prognosis, especially in canals with complex anatomy.
Review of pulp therapy in primary teeth
Authors: Allan Abuabara  , Bruno Monguilhott Crozeta  , Flares Baratto-Filho
Published: August 2022

It is extremely important for the dentist the knowledge of the signs and symptoms caused by inflammation of the pulp of primary tooth, especially when the issue is either to keep or extract it. Objective: To develop a guide to assist dentists in the diagnosis and management of pulp therapy of primary teeth. Methodology:The protocols of the American Association of Pediatric Dentistry (reviewed in 2009), the British Society of Pediatric Dentistry (reviewed in 2006) and Cochrane Library (August of 2011) were sought for the best evidence to assist managers and professionals in the most appropriate decisions for their patients. Conclusion: Regardless of the decision concerning to the primary tooth and to the different treatment modalities, attention should be directed to the prognosis of the tooth in question, by restoring its health and function.
The Effect of Whole Blood and Bone Marrow with the Addition of
Pyrimidine-2,4(1h,3h)-dione Thietanyl Derivatives on Free Radical
Oxidation
Authors: Meshcheryakova Svetlana , Kayumova Aliya , Kang Yang , Shumadalova Alina , Vinogradova Yulia , Khuzin Dinislam , Ziyakaeva Klara , Kiseleva Olga , Gabdulkhakova Irina , Beylerli Ozal , Gareev Ilgiz , Sufianov Albert , Sufianova Galina , Ahmad Aamir , Yang Guang , Guo Zidan
Published: August 2022

Background:

It is relevant to study the general patterns and identify non-specific mechanisms
of body protective and adaptive reactions violation, which can lead to the various pathological processes
and develop principles for the correction of these disorders. One of the therapy and prevention directions
is the search for new medicines. In recent years, new derivatives of pyrimidine bases have been synthesized
and studied. Pyrimidine-based medicines have a membrane-stabilizing and immunomodulatory effect
and can normalize metabolic disorders and increase the oxidative activity of leukocytes. Disruption
of the free radical oxidation processes, the generation of reactive oxygen species and lipid peroxidation,
including in whole blood and bone marrow, has gained importance in recent years.

Methods:

Each reaction was monitored by thin layer chromatography. 1H, 13C, and 15N NMR spectra
were recorded (chemical shifts were expressed as δ-values). We studied the effect of 6-methyl-3-(thietan-
3-yl)pyrimidine-2,4(1H,3H)-dione on the generation of reactive oxygen species (ROS) in the whole
blood and bone marrow using the study of whole blood spontaneous and stimulated chemiluminescence
(CL). CL methods make it possible to quickly and easily assess the studied material (whole blood, bone
marrow) effect on free radical oxidation. Using CL methods, it is possible to reveal the presence of
medicines' pro- or antioxidant properties, opening up new possibilities in the search for substances with
antioxidant properties and comparing their activity.

Results:

Alkylation of 6-methylpyrimidine-2,4(1H,3H)-dione by 2-chloromethylthiirane in protic solvents
in the presence of alkali leads to the formation of an N-thietane derivative. NMR spectroscopy
showed that 6-methylpyrimidine-2,4(1H,3H)-dione was alkylated at position 3. The oxidation reactions
of N-(thietan-3-yl)pyrimidine-2,4(1H,3H)-dione were studied, and it was determined that, depending on
the excess of the oxidizing agent and the duration of the process, N-(1-oxothietan-3-yl)- or N-(1,1--
dioxothietan-3-yl)pyrimidine-2,4(1H,3H)-diones were formed. The effects of free radical oxidation processes
of new biologically active pyrimidine-2,4(1H,3H)-diones were studied.

Conclusion:

New pyrimidine-2,4(1H,3H)-diones increase the general adaptive capabilities of the body
and have protective effects in extreme conditions.
Assessing the Influence of Salvia triloba on Memory Deficit Caused by
Sleep Deprivation in the Context of Oxidative Stress
Authors: Massadeh Adnan M. , Alzoubi Karem H. , Melhim Amal M. , Rababa’h Abeer M.
Published: August 2022

Background:

Learning and memory deficit has been reported to be correlated to oxidative
mutilation in the hippocampus. Moreover, sleep deprivation (SD) mitigates memory via distressing
oxidative stress balance. In the current report, the prospective neuroprotective role of oral sage (Salvia
triloba) extract on cognitive impairment induced by chronic SD was investigated.

Methods:

The SD was induced in adult male Wistar rats employing a modified multiple platform (8
h/day; for six weeks). Simultaneously, S. triloba extract (375 mg/kg, orally) was administered for six
weeks. Thereafter, the Radial Arm Water Maze test was utilized to evaluate spatial learning and
memory. Moreover, activities of different hippocampal antioxidant parameters: glutathione peroxidase
(GPx), oxidized glutathione (GSSG), reduced glutathione (GSH), catalase, superoxide dismutase
(SOD), and the thiobarbituric acid reactive substance (TBARS) were measured in rats’ hippocampus.
Moreover, the level of brain derived neurotrophic factor (BDNF) was assessed.

Results:

Current results illustrate that chronic SD significantly compromised both memories, shortand
long-term, while sage extract inhibited these consequences. Moreover, sage extract remarkably
stabilized the antioxidant enzyme levels, which were decreased by SD, such as: SOD, catalase, and
GPx (P <0.05), and remarkably augmented the GSH/GSSG ratio in SD rats (P < 0.05). However, no
substantial alterations of GSH, TBARS or BDNF levels (P > 0.05) were seen with sage extract administration.

Conclusion:

Chronic treatment with sage extract (S. Triloba) precluded SD-induced memory impairment
by regularizing antioxidant parameters levels in rats’ hippocampus.
Outcomes of Revision Arthroplasty for Hip Joint Infection in Matched
Groups of HIV-Positive and HIV-Negative Patients
Authors: Triapichnikov Alexander S. , Ermakov Artem M. , Malkova Tatiana A.
Published: August 2022

Background:

Several studies reported on periprosthetic infection after primary THA in
HIV-positive patients, but very few showed the results of its revision.

Objective:

The aim was to compare primary and secondary clinical outcomes after revision arthroplasty
for hip joint infection in matched groups of HIV-infected and HIV-negative patients.

Methods:

Using the hospital database, thirteen HIV-positive patients (13 infected hips) and thirteen
HIV-negative patients of the matched control group (13 infected hips) were identified and their records
were studied retrospectively. They underwent revision surgery aimed at infection arrest and
total hip replacement due to infection developed after primary THA or infected spacers. Harris Hip
Score, reinfection rate, limb shortening, and definite outcomes were evaluated with Wilcoxon,
Mann-Whitney, and Chi-squared tests.

Results and Discussion:

Spacers with antibiotics were implanted in patients of both groups at the
first step of revision, except for one HIV-infected patient who had resection arthroplasty. The mean
follow-up was 29.4 ± 2.7 and 33. ± 2.9 months for the HIV-group and control group, respectively.
Three patients of the HIV-group completed two-stage revision arthroplasty versus ten patients from
the control group. Re-infection rate was higher in the HIV-group. At final follow-ups, the mean
HHS was significantly different (53 ± 3.2 points in the HIV-group versus 79.14 ± 3.1 points in the
control group) along with limb length discrepancy (3.71 ± 0.43 versus 1.4 ± 0.32).

Conclusion:

Both primary and secondary clinical outcomes of revision arthroplasty for hip joint infection
in HIV-positive patients were significantly worse than in the matched group of HIVnegative
patients. Revisions in HIV-positive group resulted in a higher reinfection rate, a small
number of definite two-stage revisions, and lower functional scores.
Current Overview on the Role of Nanoparticles in Water Desalination Technology
Authors: Shivalingam Chitra , Mohan Laksita , Ganapathy Dhanraj , Shanmugam Rajeshkumar , Pitchiah Sivaperumal , Ramadoss Ramya , Sundramoorthy Ashok K.
Published: August 2022

Background:

Nanoparticles based thin-film has remarkable challenges in water desalination.
Carbon allotropes (carbon nanotubes, graphene sheets, and fullerene), metal and metal oxide nanoparticulates
(titanium dioxide, silver, copper oxide, alumina, zinc oxide, and metal-organic framework, silica,
halloysite, zeolite, aquaporin and cellulose) are the out breaking materials for water desalination. Advanced
materials in membrane forms are impacting the desalination processes in terms of reverse osmosis,
forward osmosis, pervaporation, membrane distillation, and electrodialysis.

Objective:

The main objective of this review is to provide a comprehensive overview of the various
methods of water desalination and the role of nanoparticles in this regard.

Methods:

We discussed the overall studies describing the process of desalination, viz. distillation, osmosis,
freeze-thaw desalination, electrodialysis, membranes, various types of nanoparticles used in desalination,
current techniques in desalination, membrane technology with Algae treatment, environmental issues
in desalination, future scopes and trials.

Conclusion:

Various polymeric membranes with graphene/carbon derivatives and nano-particulate integrated
membranes are gaining enormous attention in the field of membrane technology for the desalination
process. Nanoparticulate impregnated, and natural algae conjugated polymeric membranes may provide
a plethora of possibilities for membrane filtration technology in the near future.
YBX1 Promotes MSC Osteogenic Differentiation by Activating the
PI3K/AKT Pathway
Authors: Chen Jiayu , Liu Zhanliang , Zhang Huicheng , Yang Yongqian , Zeng Huangxiang , Zhong Rongwei , Lai Shangdao , Liao Hongxing
Published: August 2022

Introduction:

Bone metabolism has an essential role in the bone disease, but its specific mechanism remains unclear. Y-Box Binding Protein 1 (YBX1) is a gene with broad nucleic acid binding properties, which encodes a highly conserved cold shock domain protein. Previous studies have shown that YBX1 is closely related to cell differentiation. However, the function of YBX1 in osteoblast differentiation of bone marrow mesenchymal stem cells (MSCs) was unclear.

Method:

To explore the effect and specific mechanism of YBX1 in osteogenic differentiation of MSCs, we used PCR, Western blot, Alizarin red Staining, alkaline phosphatase (ALP) assays, and siRNA knockdown in our research. We found that YBX1 gradually increased during the process of osteogenic differentiation of MSCs. YBX1 siRNA could negatively regulate the MSCs osteogenic differentiation. Mechanistic studies revealed that YBX1 knockdown could inhibit PI3K/AKT pathway. Furthermore, the specific agonist (SC79) of PI3K/AKT pathway could restore the impaired MSCs osteogenic differentiation which was mediated by YBX1 knockdown. Taken together, we concluded that YBX1 could positively regulate the osteogenic differentiation of MSCs by activating the PI3K/AKT pathway.

Results and Discussion:

These results helped us further understand the mechanism of osteogenesis and revealed that YBX1 might be a selectable target in the bone repair field.

Conclusion:

Our study provides a new target and theoretical basis for the treatment of bone diseases.
Propuesta de un sistema postal de control de calidad para el sistema de planificación de tratamiento en teleterapia usando dosímetro OSL nanodot
Authors: Rodríguez Horna Ángel , Guzman Calcina Carmen Sandra , Montoya Zavaleta Modesto , Márquez Pachas José Fernando , Aymar Alejos Jesús , Méndez Velásquez Juan Abraham , Roa Dante , Alva Sanchez Mirko , Santa Cruz Delgado José , Villaverde Herrera Jessenia Brillit
Published: August 2022

Objetivo: Implementar un Sistema Postal de Control de Calidad para verificar el Sistema de Planificación de Tratamiento en Teleterapia usando dosímetros Al2O3 :C, basados en la tecnología de luminiscencia ópticamente estimulada (OSL-Optically Stimulated Luminescence), comercialmente conocidos como OSLD nanoDotTM. Materiales y Métodos: Se utilizó un maniquí que contiene dosímetros OSLD nanoDotTM, (Al2O3 :C), previamente caracterizados y calibrados para la energía de un haz de rayos x de 6.0 MV generados en un acelerador lineal, los valores de dosis absorbida fueron medidos con: una cámara de ionización Semiflex, electrómetro PTW – Freigburg, geometrías 3D de radiación, tales como: Geometría simple (campo abierto a 0º y 25º), Geometría compleja (tres campos abiertos a 0º, 90º y 270º) y Geometría combinada (campo y diversas variaciones de giro de Gantry), utilizando campos cuadrados (6cm2), circulares (diámetro 6cm), oblicuos (6cm x 6cm) e Irregulares, pesos iguales y filtros de cuña virtual en diferentes regiones del haz de fotones. Resultados: Los valores de la caracterización de los OSLD nanodot fueron: homogeneidad (0.9999), por desvanecimiento en el tiempo (0.9989), por corrección de agotamiento (0.9985), de reproducibilidad (0.9953), por dependencia angular (0.9925) y por linealidad (1.0000) para un rango de dosis absorbida 100cGy a 200cGy.  Las evaluaciones en las diferentes regiones del haz, en medio homogéneo, fueron las siguientes: Geometría simple (Incertidumbre: 3.01%), Geometría compleja (Incertidumbre: 2.16%) y Geometría Combinada (Incertidumbre: 2.62%) Conclusiones: Los resultados obtenidos se encuentran dentro de los valores de tolerancia, concluyendo que así el OSLD nanoDot TM es un dosímetro altamente confiable, además de su conveniencia en su integración en un programa de auditoria dosimétrica postal.
Evaluación de un sistema de calefacción por suelo radiante implementado en un módulo educativo-experimental construido con materiales alternativos a escala pequeña para la enseñanza superior
Authors: Alpaca Rendón Orlando Jesús
Published: August 2022

En el presente estudio se desarrolló un módulo experimental de un sistema de calefacción por suelo radiante por agua, para el laboratorio de termo-fluidos de la Universidad Católica de Santa María, con el cual se pretende comprobar si es posible emular el principio de funcionamiento térmico de este tipo de sistemas de climatización en un periodo menor a las dos horas de duración (debido a la alta inercia térmica de los sistemas radiantes y a la duración limitada de las prácticas en laboratorio), utilizando materiales alternativos que faciliten la construcción, mantenimiento y asequibilidad del módulo, manteniendo la capacidad de poder realizar pruebas experimentales de diversa índole relacionadas al suelo radiante, de manera que se evalúe la viabilidad de poder utilizar un módulo como un medio experimental con fines educativos para este tipo de sistemas. Para responder la interrogante del presente estudio, las pruebas experimentales realizadas estuvieron enfocadas en monitorear las temperaturas del suelo, del agua y del interior de la cámara de pruebas, así como el tiempo transcurrido. Los resultados muestran que, utilizando una temperatura del agua de 60°C por 60 minutos, se registraron incrementos en la temperatura interior de hasta 6.5°C, seguidamente, tras el apagado del sistema y renovación del aire interior, se registró una caída en la temperatura interior de 1.1°C durante un periodo de 30 minutos. Se implementó al módulo de manera que éste pueda ser manipulado tanto mediante una interfaz de usuario en una computadora, como sin el uso de ésta.
Laboratory Service Process Checklist: Preventive Measures to Increase Blood Glucose Test Accuracy
Authors: Setyawan Yudi , Wardhani Viera
Published: August 2022

The accuracy of the blood glucose test results is an essential measurement for hospital quality since it affects the plan, decision, and outcome of the treatment. This study aimed to develop a checklists model to improve the laboratory results accuracy. The checklist development is based on the laboratory services processes covering pre-analytic, analytic, and post-analytic stages, which are implemented in all blood glucose test requests during the study period (65 examinations), the first week of October 2020. The implementation resulted in no incidence of test inaccuracy when conformed with patient clinical information. The staff expressed that completing the checklist is quick and easy to complete (3-5 minutes) and beneficial. The problem occurs when staff works alone, causing delays in completing the checklist. Therefore, regular monitoring and evaluation are suggested to ensure compliance and divide the checklist into two stages. The pre-analytic stage is first carried out for all patients, followed by the analytical and post-analytic stages because the last two activities were located on different floors. In short, checklists are effective as preventive measures to increase the conformity of laboratory examination results with patient clinical information.
Hospital's Dental Clinic Service Readiness in Facing Covid-19
Authors: Kurniawan Gladys , Hakim Lukman , Al Rasyid Harun , Djauhari Thontowi
Published: August 2022

This research was conducted to find the root of the problem and the solution to the inactivity of X Hospital Dental Clinic since the Covid-19 pandemic. The findings from the study are expected to be an input for the hospital to be able to immediately reopen Dental Clinic services. The research design used descriptive analysis of observation data, interviews, and literature study. The Fishbone Diagram combined with 5 WHYs is used to find the root of the problem. Determination of problem solutions using the CARL method (Capability, Accessibility, Readiness, and Leverage) through the Forum Group Discussion (FGD). The results showed that the root cause of the inactivity of X Hospital Dental Clinic since the Covid-19 pandemic was the unavailability of infrastructure in accordance with the minimum standards. Therefore, X Hospital needs to procure appropriate infrastructure and support the X Hospital Dental Clinic facilities in providing services during the Covid-19 pandemic. This procurement must be adjusted to the conditions of the space and environment around the Dental Clinic and the capabilities of the hospital. The proposed adjustment is a modification to the infrastructure that will be provided and the existing Dental Clinic facilities. The infrastructure that must be provided is related to air circulation, practice room management, and patient procedures.
An Intervention Mapping Approach to Developing a Stroke Literacy Video for Recent Stroke Survivors: Development and Usability Study
Authors: Denny Mary Carter , Ancer Leal Andrea , Montiel Tahani Casameni , Wynne Keona J , Edquilang Gabrielle , Vu Kim Yen Thi , Vahidy Farhaan , Savitz Sean I , Beauchamp Jennifer ES , Sharrief Anjail
Published: August 2022

Background

Most vascular events after stroke may be prevented by modifying vascular risk factors through medical and behavioral interventions. Stroke literacy—an understanding of stroke symptoms, risk factors, and treatment—likely contributes to vascular risk factor control and in turn stroke recurrence risk. Stroke literacy is the lowest among adults belonging to racial and ethnic minority populations in the United States. Video-based interventions targeting stroke literacy may help acute stroke survivors understand stroke and subsequently reduce the risk of stroke recurrence. However, the failure of prior stroke literacy interventions may be due in part to the fact that the interventions were not theory-driven. Intervention mapping (IM) provides a framework for use in the development, implementation, and evaluation of evidence-informed, health-related interventions.

Objective

We aimed to develop a video-based educational intervention to improve stroke literacy in hospitalized patients with acute stroke.

Methods

The 6-step iterative process of IM was used to develop a video-based educational intervention and related implementation and evaluation plans. The six steps included a needs assessment, the identification of outcomes and change objectives, the selection of theory- and video-based intervention methods and practical applications, the development of a video-based stroke educational intervention, plans for implementation, and evaluation strategies.

Results

A 5-minute video-based educational intervention was developed. The IM approach led to successful intervention development by emphasizing stakeholder involvement, generation and adoption, and information retainment in the planning phase of the intervention. A planned approach to video adoption, implementation, and evaluation was also developed.

Conclusions

An IM approach guided the development of a 5-minute video-based educational intervention to promote stroke literacy among acute stroke survivors. Future studies are needed to assess the use of technology and digital media to support widespread access and participation in video-based health literacy interventions for populations with acute and chronic stroke. Studies are needed to assess the impact of video-based educational interventions that are paired with stroke systems of care optimization to reduce the risk of stroke recurrence. Furthermore, studies on culturally and linguistically sensitive video-based stroke literacy interventions are needed to address known racial and ethnic disparities in stroke literacy.

International Registered Report Identifier (IRRID)

RR2-10.1371/journal.pone.0171952
Mixed reality in Modern Surgical and Interventional Practice: a narrative review of the literature (Preprint)
Authors: Vervoorn Mats T. , Wulfse Maaike , Van Doormaal Tristan P.C. , Ruurda Jelle P. , Van der Kaaij Niels P. , De Heer Linda M.
Published: August 2022

BACKGROUND

Mixed reality and its potential applications have gained increasing interest within the medical community over the recent years. The ability to integrate virtual objects into a real-world environment within a single video-see-through display is a topic that sparks imagination. Given these characteristics, mixed reality could facilitate preoperative and pre-interventional planning, provide intraoperative and intra-interventional guidance, and could aid in education and training, thereby improving the skill and merit of surgeons and residents alike.

OBJECTIVE

In this narrative review, we provide a broad overview of the different applications of mixed reality within the entire spectrum of surgical and interventional practice and elucidate on potential future directions.

METHODS

A targeted literature search within the PubMed, Embase and Cochrane databases was performed regarding the application of MR within surgical and interventional practice. Studies were included if they met the criteria for technological readiness level 5 and as such had to be validated in a relevant environment.

RESULTS

A total of 59 studies were included and divided into studies regarding Preoperative and Interventional Planning, Intraoperative and Interventional Guidance and Training and Education.

CONCLUSIONS

Overall experience with mixed reality is positive. Main benefits of MR seem to be related to improved efficiency. Limitations primarily seem related to constraints associated with head-mounted display. Future directions should be aimed at improving head-mounted display technology, incorporation of mixed reality within surgical microscopes and robot and design of trials to prove superiority.

CLINICALTRIAL

N/A
Social Support in a Diabetes Online Community: A Mixed Methods Content Analysis (Preprint)
Authors: Da Moura Semedo Cidila , Bath Peter , Zhang Ziqi
Published: August 2022

BACKGROUND

Diabetes patients may experience different needs according to their diabetes stage. These needs may be met via online health communities (OHCs), where individuals seek health-related information and exchange different types of social support. Understanding what social support categories that may be more important for different diabetes stages may help diabetes online communities (DOCs) to provide more tailored support to online users.

OBJECTIVE

This study aimed to explore and quantify the categorical patterns of social support observed on a DOC, taking into consideration users’ different diabetes stages, including Prediabetes, Type 2 Diabetes (T2D), T2D with insulin treatment, and T2D remission.

METHODS

Data were collected from one of the largest DOC in Europe, Diabetes.co.uk. Drawing on a mixed methods content analysis, a qualitative content analysis was conducted to explore what social support categories could be identified in users’ posts. A total of 1841 posts were coded by five human annotators according to a modified version of the Social Support Behaviour Code (SSBC), including seven different social support categories: achievement, congratulations, network support, seeking emotional support, seeking informational support, providing emotional support, and providing informational support. Then, quantitative content analysis was conducted using chi-squared post hoc analysis to compare the most prominent social support categories across the different stages of diabetes.

RESULTS

Overall, seeking informational support (32.9%) and providing informational support (32.4%) were the most frequent categories exchanged among users. The overall distribution of social support categories was significantly different across diabetes stages (χ218=287.2; P<.001). Prediabetes users sought more informational support than other stages (P<.001), while there were no significant differences in categories posted by T2D users (P>.001). T2D insulin users provided more informational and emotional support (P<.001), and T2D remission users exchanged more achievement (P<.001) and network support (P<.001) than other stages.

CONCLUSIONS

This is the first study that highlights what, how and when different types of social support may be beneficial for different stages of diabetes. These findings may provide novel insights to multiple stakeholders about how these categories can be strategically used and leveraged to support diabetes management.
Design, Development, and Usability Evaluation of a Voice App Experience for Heart Failure Management (Preprint)
Authors: Barbaric Antonia , Munteanu Cosmin , Ross Heather , Cafazzo Joseph
Published: August 2022

BACKGROUND

The use of digital therapeutics (DTx) in the prevention and management of medical conditions has increased through the years with an estimated 44 million people using one as part of their treatment plan in 2021, nearly double the amount from last year. DTx are commonly accessed through smartphone apps, but offering these treatments through additional platforms can improve the accessibility of these interventions. Voice apps are an emerging technology in the digital health field; not only have they the potential to improve DTx adherence but also can create a better user experience for some user groups.

OBJECTIVE

This research aimed to identify the acceptability and feasibility of offering a voice app for a chronic disease self-management program. The objective of this project was to design, develop, and evaluate a voice app of an already existing smartphone-based heart failure self-management program, Medly, to be used as a case study.

METHODS

A voice app version of Medly was designed and developed through a user-centered design process. We conducted a usability study and semi-structured interviews with representative end users (n=8) at the Peter Munk Cardiac Clinic in Toronto General Hospital to better understand the user experience. A Medly voice app prototype was built using a software development kit in tandem with a cloud computing platform. The voice app was verified prior to the usability study and validated through user interaction and feedback. Both quantitative and qualitative data was collected and analyzed using a mixed methods triangulated convergence design.

RESULTS

Saturation was successfully achieved with the usability study, which involved eight heart failure participants. Almost all (7 out of the 8) participants were satisfied with the voice app and felt confident using it, although half of the participants were unsure about using it in the future. Six main themes were identified: changes in physical behaviour, preference between voice app and smartphone, importance of music during voice app interaction, lack of privacy concerns, desired reassurances during voice app interaction, and helpful aids during voice app interaction. These findings were triangulated with the quantitative data and concluded the main area for improvement was related to ease of use; design changes were then implemented to better improve the user experience.

CONCLUSIONS

This work offers preliminary insight into the acceptability and feasibility of a Medly voice app. We believe that offering Medly on multiple platforms (smartphone, voice user interface device) will not only increase user uptake, but also allow some patients to more easily interact with the program. With rapid advancements in voice user interfaces, we believe voice apps will play an integral role when providing access to DTx for chronic disease management.
Bedarfsanalyse Qualifizierungsoffensive. Endbericht an das Bundesministerium für Digitalisierung und Wirtschaftsstandort (BMDW)
Authors:   Technopolis | Austria, Dudenbostel Tobias , Heckenberg David
Published: August 2022

Seit 2011 unterstützt das Bundesministerium für Digitalisierung und Wirtschaftsstandort (BMDW) mit dem Programm Qualifizierungsoffensive bzw. Forschungskompetenzen für die Wirtschaft den systematischen Auf- und Ausbau von Kompetenzen von Unternehmen und ihrer Mitarbeiter*innen in den Bereichen Forschung, Technologie, Entwicklung, Innovation und Digitalisierung. Das Programm wird von der FFG administriert und umfasst heute Konsortialprojekte zwischen Wissenschaft und Wirtschaft von verschiedener Länge und Intensität (Innovationscamp S, M, und Digital Pro Bootcamp) sowie den Digital Skills Scheck. Im März 2022 hat das BMDW Technopolis mit der Durchführung einer Bedarfsanalyse zum Programm beauftragt. Die Studie ist zentral von einer durch das BMF initiierten Änderung in den Rahmenbedingungen des Programms motiviert: durch die neue Förderrichtlinie „Forschungs-, Technologie- und nnovationsrichtlinie – Humanressourcen“ können in Zukunft keine Personalkosten für die an den Schulungen teilnehmende Mitarbeiter*innen von Unternehmen gefördert werden. Damit stellt sich die Frage, was das für die Attraktivität des Programms bzw. der Förderinstrumente bedeutet und wie die Instrumente angepasst werden könnten, sodass Unternehmen weiterhin ihre Mitarbeiter*innen über diese Formate fortbilden. Darüber hinaus beantwortet die Studie Fragen zu Hemmnissen für die Teilnahme, zur thematischen und methodischen Ausgestaltung der Instrumente und präsentiert weiteres Feedback der Unternehmen und anderer Akteure (z.B. wissenschaftliche Einrichtungen, Clusterorganisationen oder regionale Innovationsagenturen).
Manejo reproductivo en bovinos lecheros para estudiantes de Medicina Veterinaria y Zootecnia
Authors:   Facultad de Medicina Veterinaria y Zootecnia, Hernández Cerón Joel
Published: August 2022

Se trata de un libro académico que ofrece a los estudiantes de la carrera de medicina veterinaria y zootecnia, particularmente a los interesados en ganado bovino, conocer las técnicas de diagnóstico y tratamientos de los desórdenes reproductivos. Desde el punto de vista zootécnico la información contempla a tres grupos de animales: vacas posparto, vacas sin servicio en el día seis posparto y vacas gestantes; analizando para cada uno de ellos la mejor manera de lograr la eficiencia reproductiva en sistemas de manejo intensivo. Con base en ello se encontrará también una descripción de los métodos de control artificial de la reproducción, que comúnmente son utilizados durante la práctica profesional en las instalaciones de un hato lechero.
Covid Future Prediction Using Machine Learning
Authors: Lakkakula Sai Sri Bhavya , Maddukuri Sai Naga Durga , Neelam Shivani , Ramasubramanian Dr. M.
Published: August 2022

Abstract: The Machine Learning models have long been used in numerous software application domains which demanded the identification and prioritization of adverse factors for a threat. Several prediction methods of machine learning domain are being popularly used to handle forecasting or soothsaying problems.Machine learning (ML) based forecasting methods have proved their significance to anticipate in perioperative outcomes to improve the decision making on the future course of actions. This study substantially demonstrates the capability of Machine Learning models to forecast the number of forthcoming patients,death cases and also recovered cases of COVID-19 which is presently considered as a implicit trouble to humanity. In particular, four standard forecasting supervised machine learning models, such as linear regression (LR), least absolute shrinkage and selection operator (LASSO), support vector machine (SVM), and exponential smoothing (ES) have been used in this study to forecast the dangerous factors of COVID-19 that we have previously discussed. Three types of predictions are made by each of the models, such as the number of recently infected cases, the number of death, and the number of recoveries in the coming 10 days. The results have been proved that the exponential smoothing (ES) performs exceptionally well among all the used models followed by LR and LASSO which performs better in forecasting the new confirmed cases, death rate as well as recovery rate, while SVM performs inadequately in all the prediction scenarios given the available dataset that has been collected from various resources.
The Analysis of Influencing Factors and Longitudinal Trend in subjective academic achievement: Focusing on affective characteristics
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Jinsu , Chung Hyewon
Published: August 2022

Objectives The purpose of this study was to analyze the longitudinal effect of affective characteristics of adolescents on academic achievement.
Methods To do this, hierarchical linear growth model was applied to the 1st to 3rd year of the 1st panel by the Korean Children and Youth Panel Survey 2018 (KCYPS 2018).
Results First, academic achievement increased linearly over the years. Second, the initial status of academic achievement appeared to be higher as creativity, monthly average income, and father's final education were higher. And emotional problems, life satisfaction, and number of siblings showed negative effect on the initial status. Third, it was found that academic enthusiasm had a significant effect on both initial status and change rate of academic achievement. Especially for the girls, the rate of change in academic achievement was in a positive direction.
Conclusions It is expected to provide basic data to discuss various teaching and learning methods for increasing academic achievement by improving students' intrinsic and affective characteristics.
An Analysis of Research Trends on Mentalizaiton: A Review of Journals in Korea
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kang Min-Jin , Lee Jee-Yon
Published: August 2022

Objectives The purpose of this study is to systematically understand the characteristics of mentalization and provide implications for future research by overviewing domestic research trends related to mentalization, which are considered one of the important cognitive-emotional abilities.
Methods For this purpose, 46 papers related to mentalization published in KCI-registered journals related to major counseling in Korea from 2001 to 2020 were analyzed for the year of publication, research subjects, research topics and analysis methods, measurement tools, research types, and psychological problem variables.
Results First, mentalization research has been on a marked increase since 2017, and the subjects of the study were mainly focused on adults. Second, in terms of research methods, all but five literature studies and three qualitative studies were all quantitative studies. Looking at this by research analysis method, 18.5 pieces (48.7%) of regression analysis were used the most, followed by 14 pieces (36.9%) of structural analysis. Third, by research topic, 34 studies on variable relations were the most common (73.9%), followed by 5 studies (10.9%) and 4 studies (8.7%) on scale development. Fourth, the most widely used measurement tool in relation to the measurement tool was the ‘mentalization questionnaire’, followed by SRMQ and Ments. Finally, most of the studies confirmed the role of mentalization in the relationship with other psychological variables using mentalization as a parameter, followed by 4 studies (11.8%), 2 studies (5.9%), and 3 studies (8.8%), respectively.
Conclusions Based on the results of this study, the main implications of mentalization research and suggestions for future research were discussed.