bluuebunny/crossref_metadata_2025 huggingface dataset:
The Emergence and Impact of Regional Research University Collaborations: The Rapidly Changing Landscape in University Research and Innovation
Authors: Duncan R.V. , Holloway James P. , Lange Richard A.
Published: January 2024

Regional universities are expanding rapidly in their research impact today. More generally, these universities are emerging rapidly in their significance and in their ability to produce rapid positive social change. Many national laboratories have developed research opportunities and
shared governance through major research university collaborations, with an emphasis on nearby educational institutions. This is expanding state-of-the-art research facilities in less populated regions of the United States that were under-capitalized in research infrastructure in the past.
Many regional research universities today are both Carnegie R1 (very high research) universities and Minority Serving Institutions, particularly R1 and Hispanic Serving Institutions (HSI). Twenty-one such educational institutions across the United States, including the University of South
Florida, which launched the National Academy of Inventors (NAI) over a decade ago, are both Carnegie R1 universities and HSIs. Given the shift in the demographics of the United States, these minority-serving R1 research universities are likely to gain in their influence, impact, and prestige
rapidly over the years to come. This paper provides a summary of the NAI panel discussion and more background information on this important topic.
Yörük Mutfak Kültürünün Sürdürülebilirliği: Engeller, Çözüm Önerileri ve Gastronomi Turizmi Açısından Değerlendirilmesi (Sustainability of Yoruk Culinary Culture: Obstacles, Solution Proposals and Its Evaluation in Terms of Gastronomy Tourism)
Authors: YILDIRIM Oya , KARACA Oya Berkay
Published: January 2024

Çalışmada, Yörük mutfak kültürünün sürdürülmesinin önündeki engelleri tespit etmek, kültürün sürdürülebilmesi ve gelecek kuşaklara aktarımı için çözüm yolları sunabilmek ve bölge gastronomisi için önemini ortaya koymak amaçlanmıştır. Nitel araştırma yöntemlerinden görüşme yönteminin kullanıldığı çalışmada veriler yarı yapılandırılmış görüşme formu ile toplanmıştır. Araştırmanın evrenini Mersin ve Adana il sınırları içerisinde yaşayan Yörük kökenli vatandaşlar oluşturmaktadır. Amaçlı örnekleme yöntemlerinden kartopu örnekleme yöntemi kullanılarak 01 Haziran 2022-05 Temmuz 2023 tarihleri arasında 20 kişi ile yüz yüze görüşmeler gerçekleştirilmiştir. Elde edilen veriler MAXQDA programına aktarılmış ve içerik analizine tabi tutulmuştur. Araştırma sonucunda, Yörük mutfak kültürünün sürdürülmesinin önündeki engeller; ekonomik, yaşam şekli ve kültür aktarımı ile ilgili engeller olmak üzere üç kategoride toplanmıştır. Yaşam koşullarının değişmesi, kentleşme ve kültürü sürdürmek için uygun ortamların bulunamaması ilk üç engel olarak belirlenmiştir. Kültürü sürdürebilmek için en önemli çözüm önerisi ise kültürel öğelerin yeni nesillere doğru aktarılması şeklinde tespit edilmiştir. Yörük mutfak kültürünün bölgenin yerel lezzetleri ile tanınmasında etkili olacağı ve yerel ürünlere ilgi duyan turistler için bir çekim unsuru olacağı araştırmanın bulguları arasındadır.
Konaklama İşletmelerinde Çevresel Tutku Algısının Küresel Sosyal Sorumluluğa Etkisi (The Effect of Perception of Environmental Passion on Global Social Responsibility in Accommodation Businesses)
Authors: GÜDÜL Ayşegül , SAĞIR Mehmet
Published: January 2024

Günümüzde özellikle insan kaynaklı faaliyetlere bağlı olarak çevresel sorunların artması herkesin önlem almasını gerektirirken, işletmeler de bu sorunların azalmasına yardımcı olmalıdır. Turizm sektörünün çevreyle etkileşiminin ve verdiği zararın fazla olması göz önüne alındığında sektör çalışanlarının çevresel tutkuya ve küresel sosyal sorumluluk davranışına sahip olması beklenmektedir. Bu çalışmanın amaçları dahilinde, çevre dostu 5 yıldızlı konaklama işletmeleri yöneticilerinin küresel sosyal sorumluluk ve çevresel tutkusu arasındaki ilişki düzeyleri araştırılmış, aralarında pozitif ve anlamlı bir ilişki olduğu tespit edilmiştir. Aynı zamanda çevresel tutkunun küresel sosyal sorumluluk üzerinde etkisi araştırılmış, anlamlı ve pozitif etkisi olduğu sonucuna ulaşılmıştır. Demografik özelliklerin çevresel tutku algısında anlamlı fark ortaya koyup koymadığının da araştırıldığı bu çalışmada, cinsiyet, eğitim düzeyi ve mevcut iş yerinde toplam çalışma süresi değişkenlerinde anlamlı farklılık olduğu, yaş, medeni durum ve yönetici düzeyine göre anlamlı farklılık olmadığı sonucuna ulaşılmıştır.
Gastronomic Tourism of Türkiye: A Study on the Polish Market
Authors: EREN Erdi , ÇOŞKUN Kemal , TAŞÇI Tamer
Published: January 2024

Gastronomy is defined as a discipline that studies the preparation, presentation, and consumption of food and beverages within the framework of the relationship between food and culture. Gastronomy tourism focuses on the search for new flavors in new locations to improve one's physical and mental health. Türkiye hosts a wide variety of tourism types and opportunities with its historical texture, natural beauty, and rich cultural pool. Gastronomy tourism is one of these rich tourism opportunities. Türkiye hosts millions of tourists from various countries around the world every year. In 2022, approximately 2.2% of foreign visitors to Türkiye were Polish tourists. This study determined the preferences and opinions of Polish tourists regarding Türkiye's gastronomy tourism market. According to the data obtained, 101 male and 282 female participants indicated that Turkish cuisine and Turkish gastro-tourism have an essential place in the world, gastronomic elements are an important factor in their preference for Türkiye, they find Turkish cuisine predominantly delicious and affordable, döner kebab and Turkish coffee are the most well-known food and beverages from Turkish cuisine, and the participants are planning to revisit Türkiye for gastronomy tourism. As a result of the study, gastro-tourism-oriented recommendations were given to the sector for Turkish cuisine to take a more active role in the country's tourism and for the Polish market to be utilized more effectively.
Yeni Bir Araştırma Alanı Olarak Dijital Oyunlarda Gastronomi (Gastronomy in Digital Games as a New Research Area)
Authors: ISLAKOĞLU Ünal Gönen , ÖZÇETİN Mehmet
Published: January 2024

Literatürde gastronomi konulu dijital oyunları inceleyen bir çalışmaya rastlanamaması sebebiyle bu araştırma gastronomi konulu oyunları araştırmayı amaçlamıştır. Bu bağlamda nitel araştırma yöntemi benimsenmiş olup Steam platformunda “aşçılık” etiketiyle satışa sunulmuş olan 428 bilgisayar oyunu arasında “En İyiler” ve “En Çok Satanlar” listelerinin ilk 25 sırasında yer alan oyunlar araştırmanın örneklemini oluşturmaktadır. Oyunların çoğunlukla işletme yönetimi tarzında simülasyonlar olduğu ve müşteriler tarafından beğenildiği görülmüştür. Ayrıca iki listenin kesişim kümesinde yer alan oyunlar belirlenmiş ve satışa sunulduğu etiketler kelime bulutu aracılığıyla analiz edilmiştir. Son olarak kesişim kümesinde yer alan oyunların iki listede yer aldığı sıranın ortalaması hesaplanarak yeni bir sıralama oluşturulmuş ve yeni sıralamada ilk üçte bulunan oyunlar detaylı bir şekilde incelenmiştir. Araştırmanın bir kazanımı olarak gastronomi ile dijital oyunlar arasındaki ilişkinin kurulmasına öncülük ederek yeni araştırmalar için önerilerde bulunulmuştur.
Gastronomik Bir Miras Trakya Kuskusu; Çatalca Örneği (Thracian Couscous as Gastronomic Heritage; The Case of Çatalca)
Authors: AKSU Kemal , SARPER Fulya
Published: January 2024

Türk mutfağında geleneksel üretim metotları kullanılarak hazırlanan ürünlerden biri kuskustur. Kendine özgü araç-gereçleri, imece usulü hazırlık süreci ve yüksek besin değerine sahip olmasıyla diğer ürünlerden ayrılmaktadır. Özellikle Trakya bölgesinde Balkan göçmeni nüfusun yoğun yaşadığı bölgelerde geleneksel üretimi devam eden kuskus, nüfusun yaşlanması ve genç nüfusun ilgisini kaybetmesi dolayısıyla kaybolma ve unutulma tehlikesindedir. Bu sebeple kuskus yapımının devam ettiği Trakya’nın doğudaki başlangıç noktası olan İstanbul ili Çatalca ilçesinde görüşmeler gerçekleştirilerek güncel durum hakkında bilgi alınmıştır. Amaçlı örnekleme yöntemlerinden ölçüt örnekleme yönteminin kullanıldığı bu çalışmada Çatalca ilçesinde bulunan 35 kırsal mahallenin muhtarlarıyla görüşülmüş ve 9 mahallede kuskus yapımının artık devam etmediği öğrenilmiştir. Kuskus yapımı devam eden mahallelerden 50 yaş ve üzeri 18 katılımcı ile yarı yapılandırılmış görüşmeler yapılmıştır. Görüşmeler sonucunda literatürde yer almayan buharda pişirilip kurutma sürecinin katılımcılar aracılığıyla aktarımı sağlanmıştır. Katılımcılar yaşlı nüfusun artık kuskus yapmakta zorlandığı ve gençlerin hazır market ürünlerine yöneldiğini, kuskus yapan aile sayısının azaldığını belirtmişlerdir.
Ekonomik Krizler ve Pandeminin Türk Turizm Sektörüne Etkilerinin İncelenmesi (Investigation of The Effects of Economic Crises and Pandemic on Turkish Tourism Sector)
Authors: TÜRKMEN N. Ceren
Published: January 2024

Bacasız sanayi olarak da adlandırılan turizm sektörü, Türkiye için yapısal-kronik ödemeler dengesi açıklarının azaltılması, döviz geliri elde edilmesi, istihdam olanaklarının yaratılması gibi hususlar açısından bakıldığında kritik öneme sahip sektörlerden biridir. Bu çalışma, turizm sektörünün ekonomik kalkınma açısından kritik önemine odaklanmakta ve Türk turizm sektöründe yaşanan ekonomik krizlerin ve 2020 pandemisinin makroekonomik etkilerini incelemektedir. 1994, 2001, 2008 finansal krizleri ve 2020 pandemi sürecinin sektöre olan etkileri hem kavramsal hem de karşılaştırmalı bir bakış açısıyla ele alınmıştır. Krizlerin yapıları, nedenleri, süreçleri ve Türk ekonomisi üzerindeki etkileri, turizm sektörü üzerinde nasıl bir değişim oluşturduğu irdelenmiştir. Krizlerin ve pandeminin firmalar, istihdam, döviz, faiz oranları üzerinde yarattığı olumsuzluklar da ele alınarak, bu olayların sektörü nasıl etkilediği ve bunlara nasıl adaptasyon sağlandığı üzerinde durulmuştur. Makale, turizm sektörünün krizlerin etkisi altındaki çeyrek yüzyılı aşkın bir döneminin incelenmesi ile özgün bir katkı sağlamaktadır. Bu bağlamda, krizlerin Türk turizmine olan etkileri analitik olarak değerlendirilmiş ve bu bulgular ışığında öneriler sunulmuştur.
Invariant approach to the driven Jaynes-Cummings model
Authors: Bocanegra-Garay Ivan Alejandro , Hernández-Sánchez L. , Ramos-Prieto Irán , Soto-Eguibar Francisco , Moya-Cessa Héctor Manuel
Published: January 2024

We investigate the dynamics of the driven Jaynes-Cummings model, where a two-level atom interacts with a quantized field and both, atom and field, are driven by an external classical field. Via an invariant approach, we are able to transform the corresponding Hamiltonian into the one of the standard Jaynes-Cummings model. Subsequently, the exact analytical solution of the Schrödinger equation for the driven system is obtained and employed to analyze some of its dynamical variables.
Training on Digital Marketing and Redesign of Ecoenzyme Product Packaging Enhances the Productivity of ‘Sri Tanjung SMEs’
Authors: Maulida Faishal Hilmy , Kusuma Yudhistya Ayu , Shanti Mardhatillah
Published: January 2024

Sri Tanjung is one of the Small & Medium-Sized Enterprises (SMEs) operating in a green economy in Sukosari Village, Kasembon District, Malang Regency. The SMEs make a variety of eco-enzyme-based soaps. This community service aims to address the production and marketing-related issues that Sri Tanjung SMEs deal with. Observation and training tailored to the requirements of Sri Tanjung SMEs constitute the method adopted. Among the conclusions reached are the necessity to enhance manufacturing capacity, which is still constrained by a shortage of human resources; the fact that sales of soap only satisfy local demands using traditional techniques; and the fact that human resources still lack marketing technology skills. Conclusions and suggestions that can be made include training on the usage of Google Business and Google Ads, as well as training on the production and marketing aspects of digital marketing through social media (marketing aspect).
Analysis of The Effect of Brand Image and Perceived Quality on Customer Loyalty Through Customer Satisfaction as an Intervening Variable (Case Study PT. Sempurna Sukses Sejati)
Authors: Sherly Sherly
Published: January 2024

To improve the company's performance in overcoming the tight competition in the stationery industry at this time, research should be conducted on how the brand image of ESCO products in the minds of consumers and how the perception of the quality of ESCO products according to consumers who use them. This research was conducted to find out how far the ESCO brand products have developed in the community and whether they can compete in the market with various brands and similar products. Therefore, this study also wants to analyse the extent to which consumers are loyal to the brand and how far the satisfaction has been obtained. Consumer satisfaction is something that can encourage consumers to be more loyal to a brand and consumer loyalty to the brand is very important for the company because it will bring long-term profit and benefits to the company's products in the future.
Analysis, Findings, and Recommendations for Needs/Problems Assessment and Clustering of UMKM Assisted by CDA Unit Binus University
Authors: Heriyati Pantri , Dewanti Retno
Published: January 2024

Center For Business and Empowerment (CBSE) has committed to synergize and support the CDA Binus University. Coaching activities for Binus University-assisted MSMEs will develop from the previous activities which focused on providing competency and expertise training to Binus University-assisted MSME players by Binus University lecturers. As for improving the coaching program and to be more focused, CDA wants the MSME participants to be clusterized/categorized and then assessed or assessed their needs. The development model of computerization and needs assessment as well as the development of empowerment programs and curriculum for MSMEs assisted by BINUS hang includes 4 main stages and 1 reporting stage.
Analysis of The Effect of Electronic Customer Relationship Management and Perceived Value on E-Customer Loyalty Through E-Customer Satisfaction on XYZ.Com
Authors: Wijaya Deborah , Dewanti Retno
Published: January 2024

Electronic Customer Relationship Management is an integrated CRM function with the use of an online environment to identify, attract and retain an organization’s customers. E-CRM has an important role in addressing the challenges that exist in the e-commerce industry and certainly affect the success of e-commerce. In an online business, perceived value is something that must be maintained, that it can become a company's advantage in competing. The purpose of this research is to identify the effect of Electronic Customer Relationship Management (E-CRM) and Perceived Value in increasing customer satisfaction and loyalty. This study used the method SEM-PLS with respondents as mush as 111 respondents. The results are significant againts Electronic Customer Relationship and Perceived Value on E-Customer Satisfaction and E-Customer Loyalty in JABODETABEK customer of XYZ.com.
Disaster Preparedness from House for Earthquake-Prone Area in Sukabumi Area, West Java
Authors: Sofiana Yunida , Retnaning Nabilla , Chadijah Siti
Published: January 2024

Indonesian territory is located in a region that is prone to earthquake disasters. Therefore, there is a need to educate the community about emergency scenarios related to earthquake disasters since they can happen at any time. One of the preventive measures that can be taken is how the community can arrange the interior of the house so that the house is safer and prevent the furniture from endangering the occupants of the house in the event of a disaster, especially an earthquake. This community service's goal is to foster community interaction through the creation of a furniture arrangement workshop inside the home to decrease risk. The strategy is implemented through a session on home organization. The strategy used takes the form of a workshop on how to set up homes safely. From the results of the workshop, it is envisaged that the community would be better able to comprehend how to arrange furniture in the home to prevent accidents. Workshops are provided in the form of pictures and tutorials along with examples of before and after arrangements to help the community better understand the layout of furniture that is under safety.
Decadal changes in land use and land cover: impacts and their influence on urban ecosystem services
Authors: Nayak Deeksha , Shukla Anoop Kumar , Devi Nandineni Rama
Published: January 2024

The steady growth of cities alters the urban environmental pattern and functions, posing significant challenges to urban ecological as well as environmental governance. Under this setting, analyzing the relationship between urban growth and ecological services is critical for management and policy-related sustainable urban development. The primary goal of this research is to analyse the dynamic urbanization and its influence on urban ecosystem services via changes in LULC of Mangaluru city agglomeration, India. For five decades (1980,1990, 2000, 2010, and 2022), the ecosystem service values (ESVs) are analysed using remote sensing data and Geographic Information System (GIS) techniques corresponding with the global value coefficient (VC) to estimate total ecosystem service values (ESVt) and individual ecosystem service function change. The study shows that ecosystem service values (ESVs) declined by US$ 116.89 million to US$ 85.14 million due to 9.54 and 63.44% decreases in agricultural land and wasteland/shrubland between 1980 and 2022. In terms of individual ecosystem service functions, regulating services increased from 1980 to 2022, with nutrient cycling (45.64%), raw material (15.59%), and erosion control (12.13%) contributing the most. The loss in total and certain individual ESV in the study landscape necessitates immediate action to improve urban ecosystem sustainability via proper planning and policy.
Grób podporucznika artylerii konnej Królestwa Polskiego Bonawentury Kuźniczowa w kolegiacie łowickiej – przyczynek do genealogii rodziny Kuźniczowów
Authors: Kamińska Monika , Szczepanek Anita , Wrzosek Jakub
Published: January 2024

Grób Bonawentury Kuźniczowa, zmarłego w 1829 r. żołnierza Wojska Polskiego, został znaleziony w jednej z krypt katedry w Łowiczu. Zachowane wyposażenie grobu może uzupełnić studia nad umundurowaniem Wojska Polskiego okresu Królestwa Kongresowego. Powód, dla którego żołnierz został pochowany w ówczesnej kolegiacie, pozostaje nieznany. Przeprowadzona kwerenda stała się jednak przyczynkiem do odtworzenia drzewa genealogicznego rodziny Kuźniczowów.
Wartość historyczna więziennych listów biskupa Czesława Kaczmarka do prymasa Stefana Wyszyńskiego (1951–1953)
Authors: Gryz Ryszard
Published: January 2024

W artykule podjęto próbę oceny wartości merytorycznej dziewiętnastu więziennych listów biskupa Czesława Kaczmarka do prymasa Stefana Wyszyńskiego. Nie trafiły one do adresata, lecz w ręce oficerów śledczych komunistycznego aparatu bezpieczeństwa w czasie między aresztowaniem w styczniu 1951 roku a pokazowym procesem hierarchy we wrześniu 1953 roku. Treść obejmuje opis warunków więziennych, listę zarzutów, metod śledztwa i fabrykowania dowodów oraz prezentację strategii obronnej biskupa, a także ewolucji jego stanu psychofizycznego. Korespondencja biskupa do prymasa umożliwi analizę źródeł archiwalnych pochodzących z przewlekłego postępowania pseudodowodowego.
Salzburskie pochodzenie łacińskiego tekstu Pontificale Plocense I
Authors: Misiarczyk Leszek
Published: January 2024

Artykuł przedstawia syntetyczne wyniki badań porównawczych tekstu łacińskiego Pontificale Plocesne I (PP) z kodeksami z Bambergu (B) i Vendôme (V). Taka metoda analiz została zastosowana po raz pierwszy w badaniach nad Pontyfikałem Płockim i stanowi uzupełnienie wcześniejszych studiów. Analizy porównawcze wykazały, że 60 z wszystkich 81 obrzędów obecnych w Pontyfikale Płockim występuje w kodeksach B i V dokładnie w takiej samej wersji albo tylko z niewielkimi zmianami, co daje 74% zgodności. 12 obrzędów z Pontyfikału Płockiego nie występuje w ogóle w kodeksach B i V (14,8%), natomiast pozostałe 9 (11%) występuje w rękopisach B i V, ale ich tekst jest inny niż PP. Ponieważ wiadomo, że kodeksy B i V powstały w Salzburgu, ogromna liczba podobieństw Pontyfikału Płockiego z B i V wskazuje wyraźnie, że jego tekst łaciński reprezentuje wersję salzburską PRG, a nie moguncką. Wyniki tych badań zaskakują całkowicie, gdyż do tej pory nikt nie sugerował pochodzenia tekstu Pontyfikału Płockiego z kręgu Salzburga ani wpływów kościelnych stamtąd na Płock w XII wieku, co nie jest dowodem na to, że dokładnie tam został spisany.
Polysulfone and cellulose acetate-based membranes' potential application to photocatalytic membrane reactors
Authors:   National Research and Development Institute for Industrial Ecology, Constantin Lucian Alexandru , Constantin Mirela Alina ,   National Research and Development Institute for Industrial Ecology, Ionescu Ioana Alexandra ,   National Research and Development Institute for Industrial Ecology, Puiu Maria Diana ,   National Research and Development Institute for Industrial Ecology
Published: January 2024

Polysulfone (Psf) and Cellulose acetate (Ac-Cel) based membranes were synthesized via immersion precipitation–phase inversion techniques, starting from initial polymeric solutions with concentrations of 8%, 10%, and 12%. Each membrane was characterized from a morphological point of view by scanning electronic microscopy and from compositional point of view by thermal analyses. Hydrodunamic characteristics were also determined for all membranes using both ultrapure water and real municipal wastewater. Obtained results proved that polysulfone and cellulose acetate based membranes are potential candidates to be used for advanced treatment of municipal wastewater using photocatalytic membrane reactors.
Investigation of mesh independence in numerical modeling of sharp-crested weirs at different heights
Authors:   Konya Technical University, Yildiz Ali
Published: January 2024

Mesh independence is a term used in numerical analysis and simulation to refer to a situation where the numerical solution of a problem is insensitive to changes in the size or density of the computational mesh used to discretize the problem domain. In other words, a numerical solution is said to be mesh independent if it remains stable and accurate even when the mesh is refined. This is important because the accuracy and stability of numerical simulations depend on the quality of the mesh used to discretize the problem domain. The shape, size, and number of meshes used while performing numerical modeling in accordance with flow physics in the solution of hydraulic problems significantly affect the result. In this study, a total of 12 experiments were carried out for 4 different discharge values (Q=5 L/s, 10 L/s,15 L/s and 20 L/s) for sharp-crested weirs with three different weir heights (P=20 cm, 30 cm and 40 cm). Numerical models of each experimental setup with four different mesh sizes (m=1.25 mm, 2.50 mm, 5.00 mm and 10.00 mm) were created with the ANSYS-Fluent program. Numerical analyses were performed using the grid resolution method to obtain a mesh size-independent result where the mesh size would not affect the results after the specified error rate.
Experimental and numerical modeling of bridge piers having a different numbers of axis
Authors:   Konya Technical University, Kayhanlar Goknur Elif Yarbasi , Yarar Alpaslan ,   Konya Technical University
Published: January 2024

The interaction of bridge piers and currents with each other is mutual. As a result of this interaction, it has been determined that one of the main causes of damage to bridges is the scouring of bridge piers. One of the factors on which the scouring procedure depends is the flow velocity. For this reason, in this study, the velocity distributions that occur before the bridge piers, which are positioned as single axis and double axis, were examined physically and numerically. In experimental studies, the reading values obtained by using ADV were compared with the results obtained from the ANSYS-Fluent package program used in numerical modeling. The performance of the model used and the effects of placing the piers as single axis and double axis were evaluated. As a result of the study, it was determined that the ANSYS used in determining the flow velocity area was very compatible with the experimental results and that the flow velocity acting in the system obtained by placing the bridge piers as a single axis is larger.
Carbon Nanotubes for Targeted Therapy: Safety, Efficacy, Feasibility and
Regulatory Aspects
Authors: Gupta Babita , Sharma Pramod Kumar , Malviya Rishabha
Published: January 2024

It is crucial that novel and efficient drug delivery techniques be created in order to improve the pharmacological
profiles of a wide variety of classes of medicinal compounds. Carbon nanotubes (CNTs) have recently
come to the forefront as an innovative and very effective technique for transporting and translocating
medicinal compounds. CNTs were suggested and aggressively researched as multifunctional novel transporters
designed for targeted pharmaceutical distribution and used in diagnosis. CNTs can act as vectors for direct
administration of pharmaceuticals, particularly chemotherapeutic medications. Multi-walled CNTs make
up the great majority of CNT transporters, and these CNTs were used in techniques to target cancerous cells. It
is possible to employ Carbon nanotubes (CNTs) to transport bioactive peptides, proteins, nucleic acids, and
medicines by functionalizing them with these substances. Due to their low toxicity and absence of immunogenicity,
carbon nanotubes are not immunogenic. Ammonium-functionalized carbon nanotubes are also attractive
vectors for gene-encoding nucleic acids. CNTs that have been coupled with antigenic peptides have the potential
to be developed into a novel and efficient approach for the use of synthetic vaccines. CNTs bring up an
enormous number of new avenues for future medicine development depending on targets within cells, which
have until now been difficult to access. This review focuses on the numerous applications of various CNT
types used as medicine transport systems and on the utilization of CNTs for therapeutical purposes.
Bibliometric Analysis to Improve Combined Treatment Strategies for
Glioblastoma in America
Authors: Molina-García José , Vázquez David , Piñón Ernesto , Portilla Alonso , Tena-Suck Martha Lilia , Lee Angel , Rubio Carmen
Published: January 2024

Introduction:

Bibliometric analysis quantitatively examines scientific literature to extract
insights. This article has conducted such analysis on glioblastoma multiforme (GBM) treatment articles.
GBM, a prevalent brain tumor, is typically treated with surgery, radiation, and chemotherapy.

Objectives:

The article aimed to bibliometrically analyze articles discussing combined GBM treatment
to identify impactful research areas and encourage collaboration.

Materials and Methods:

The study encompassed a comprehensive search in the Scopus database,
spanning articles published from 1974 to 2022. Inclusion criteria encompassed research conducted in
the Americas, both clinical and experimental. A total of 772 articles were collected and categorized
based on their primary focus on combined treatment approaches.

Results:

Clinical studies constituted 52% of articles, suggesting a slight dominance. The analysis unveiled
key research moments, including a 1998 focus shift and a pivotal 2005 study on temozolomide-
radiation combination. Top journals, trends, and authors were identified, with the USA
leading in contributions.

Discussions:

Despite high brain tumor incidence, research distribution discrepancy is concerning.
Regional epidemiological studies have been endorsed. The dominance of US and German authors in
GBM collaboration has raised equity issues due to budget and GDP disparities limiting Latin American
representation.

Conclusion:

GBM research in the region is dominated by the USA, while contributions from Latin
American countries remain limited. The absence of comprehensive epidemiological studies on GBM
in Latin America is concerning, considering the evident impact of the disease in the region. This underscores
the urgent need for increased research participation and collaboration to advance the understanding
and treatment of GBM across Latin American nations.
Method Development and Validation for Simultaneous Detection of
Corticosteroids, Small Peptides, SARMs and Quaternary Ammonium
Drugs in Camel Urine for Doping Control Applications
Authors: Nalakath Jahfar , P.T. Rasik , O.K. Praseen , P. Shamil , Selvapalam N. , Nagarajan E.R.
Published: January 2024

Background:

Detection and identification of a wide range of drugs, including small peptides,
corticosteroids, selective androgen receptor modulators (SARMs), and quaternary ammonium
drugs (QADs), are imperative across several domains, particularly in anti-doping analysis, given the
potential misuse of these substances in animal sports, there is an urgent demand for an allencompassing
screening method to effectively identify these compounds.

Objective:

To develop a robust and sensitive high-resolution method for simultaneous screening of
small peptides, corticosteroids, SARMs, and QADs using liquid chromatography accurate mass spectrometry
in post-race urine samples. This method integrates a streamlined single-stage extraction
approach, significantly enhancing efficiency and adaptability for screening drugs across various classes.

Methods:

The method development and validation involved a comprehensive solid-phase extraction
protocol, which included a sequential elution for corticosteroids, small peptides, SARMs, and QADs.
Chromatographic separation was achieved using a reverse-phase C18 column, and the analysis was
performed using liquid chromatography - high-resolution accurate mass spectrometry.

Results:

The developed method was validated using a selection of drugs representing each class. The
method exhibited robustness and sensitivity, enabling the simultaneous screening of the specified
drug classes. The flexibility inherent in the proposed extraction and analysis method allows for
seamless integration of new drug candidates eliminating the need for method redevelopment.

Conclusion:

A versatile and effective screening method was successfully developed and validated for
the simultaneous detection of small peptides, corticosteroids, SARMs, and QADs. The method's ability
for retrospective analysis of emerging drugs using full scan HRMS enhances its utility. This method holds
great promise across various fields where accurate and comprehensive drug screening is imperative.
An Approach for Evaluation and Recognition of Facial Emotions Using
EMG Signal
Authors: Maity Sourav , Veer Karan
Published: January 2024

Background:

Facial electromyography (fEMG) records muscular activities from the facial
muscles, which provides details regarding facial muscle stimulation patterns in experimentation.

Objectives:

The Principal Component Analysis (PCA) is mostly implemented, whereas the actual or
unprocessed initial fEMG data are rendered into low-spatial units with minimizing the level of data
repetition.

Methods:

Facial EMG signal was acquired by using the instrument BIOPAC MP150. Four electrodes
were fixed on the face of each participant for capturing the four different emotions like happiness,
anger, sad and fear. Two electrodes were placed on arm for grounding purposes.

Results:

The aim of this research paper is to propagate the functioning of PCA in synchrony with the
subjective fEMG analysis and to give a thorough apprehension of the advanced PCA in the areas of
machine learning. It describes its arithmetical characteristics, while PCA is estimated by implying the
covariance matrix. Datasets which are larger in size are progressively universal and their interpretation
often becomes complex or tough. So, it is necessary to minimize the number of variables and
elucidate linear compositions of the data to explicate it on a huge number of variables with a relevant
approach. Therefore, Principal Component Analysis (PCA) is applied because it is an unsupervised
training method that utilizes advanced statistical concept to minimize the dimensionality of huge datasets.

Conclusion:

This work is furthermore inclined toward the analysis of fEMG signals acquired for four
different facial expressions using Analysis of Variance (ANOVA) to provide clarity on the variation
of features.
Uji Antimikroba Ekstrak Kapang Endofit RLC 5 Akar Tanaman Kayu Jawa (Lannea coromandelica (Houtt.) Merr.)
Authors:   Prodi Farmasi Fakultas Farmasi Institut Sains dan Teknologi Nasional (ISTN), Bahri Saiful , Christy Theodora ,   Prodi Farmasi Fakultas Farmasi Institut Sains dan Teknologi Nasional (ISTN), Nanda Setiawan Yulius ,   Prodi Farmasi Fakultas Farmasi Institut Sains dan Teknologi Nasional (ISTN), Septianingsih Vina ,   Prodi Farmasi Fakultas Farmasi Institut Sains dan Teknologi Nasional (ISTN), Ikhsan Muhammad ,   Prodi Biologi Fakultas Sains dan Teknologi Universitas Islam Negeri (UIN) Syarif Hidayatullah, Triutami Feby ,   Kelompok Studi Generation of Microbiology and Molecular (GENOM) Universitas Islam Negeri (UIN) Syarif Hidayatullah, Noviyanti Annisa ,   Kelompok Studi Generation of Microbiology and Molecular (GENOM) Universitas Islam Negeri (UIN) Syarif Hidayatullah, Permata Utari Andini Putri ,   Kelompok Studi Generation of Microbiology and Molecular (GENOM) Universitas Islam Negeri (UIN) Syarif Hidayatullah, Ramadhan Firdaus ,   Laboratorum Mikrobiologi Fakultas Farmasi Institut Sains dan Teknologi Nasional (ISTN)
Published: January 2024

Java root (Lannea coromandelica (Houtt.) Merr.) contains many saponins, steroids and alkoloids which are known to have potential as antimicrobials. This study aims to examine the antimicrobial activity of isolates of endophytic molds from the roots of Javanese wood plants with RLC code 5 against pathogenic fungi and bacteria. The research was carried out by rejuvenating RLC 5 isolates for 7 days and then carrying out macroscopic and microscopic characteristics. Fermentation was carried out for 21 days to reach the stationary phase in producing secondary metabolites, then extraction was carried out from the fermented RLC 5 isolate using a vacuum rotary evaporator. The metabolite screening test was carried out by testing for flavonoids, saponins, tannins, alkaloids, and triterpenoids and steroids. Antimicrobial testing was carried out using the disc diffusion method to see the clear zones that formed. The results showed that the endophytic mold RLC 5 is a mold of the genus Penicillium which is capable of synthesizing secondary metabolites in the form of saponins, alkaloids and steroids. The antimicrobial properties of the supernatant extract of the RLC 5 mold isolate were stronger than the biomass extract, with inhibition zones respectively of 9.03 mm, 11.09 mm and 19.83 mm against Candida albicans, Malassezia furfur and Trichophyton mentagrophytes and 12.51 mm and 13.03 mm against Bacillus subtilis and Escherichia coli. Thus, RLC 5 mold has the potential to become a fungicide and biostatic antibiotic for pathogenic microbes. Keyword : Antimicrobial, Endophytic mold, Lannea coromandelica, Java Wood Plant, RLC 5 isolate
Efektivitas Aktivitas Antibakteri Ekstrak Etanol 70% Daun Mimba (Azadirachta indica A. Juss) Dari Praya Lombok Tengah Dan Seyegan Sleman Yogyakarta Terhadap Staphylococcus aureus Dan Escherichia coli Secara In Vitro Serta Skrining Fitokimia
Authors:   Departemen Biologi, Jurusan Biologi Industri , Fakultas MIPA Universitas Ahmad Dahlan, Yogyakarta, Indonesia, Ary Widodo Ageng , Hendriyani Irmatika ,   Departemen Kimia Farmasi, S1 Farmasi, Fakultas Ilmu Kesehatan Universitas Muhammadiyah Mataram, Mataram, Indonesia
Published: January 2024

Nimba (Azadirachta indica A. Juss) is a plant that is widely used as traditional medicine and contains a class of flavonoid compounds, saponins, tannins and polyphenols. This study aims to determine the differences in the class of antibacterial compounds contained in plants and the activity of 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss) from Seyegan, Sleman, Yogyakarta and Praya, Central Lombok, Lombok against Escherichia coli and Staphylococcus aureus. Extraction of nimba leaves (Azadirachta indica A. Juss) using 70% ethanol as a solvent. The extract was tested on Escherichia coli and Staphylococcus aureus bacteria. Minimum Inhibitory Concentration (MIC) was tested using the liquid dilution method, variations in the concentration of sample solution 50% w/v, 25% w/v, 12.5% w/v, 6.25% w/v, 3.125% w/v and 1.56% w/v , the minimum kill concentration (MBC) was determined from the lowest observed concentrations on McConkey's medium for Escherichia coli and Blood Agar for Staphylococcus aureus. Phytochemical screening of the 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss ) was carried out with a tube to determine the class of active compounds in the 70% ethanol test of neem leaves (Azadirachta indica A. Juss ) from different growing sites. The results of 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss) could not be determined because the test solution looked cloudy. Meanwhile, the KBM of 70% ethanolic extract of nimba (Azadirachta indica A. Juss ) on Escherichia coli bacteria was 25% w/v of 70% ethanol extract of nimba (Azadirachta indica A. Juss ) leaves from Seyegan, Sleman, Yogyakarta and 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss ) from Praya, Central Lombok, Lombok is 25%w/v. Minimum kill concentration against Staphylococcus aureus was 6.25% w/v 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss) from Seyegan, Sleman, Yogyakarta and 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss) from Praya, Central Lombok, Lombok is 6.25% b/. The test results of the 70% ethanol extract of nimba leaves (Azadirachta indica A. Juss) from Seyegan, Sleman, Yogyakarta and Praya, Central Lombok, Lombok contained flavonoid compounds, saponins, tannins, and polyphenols. Keyword : Antibacteria, Nimba (Azadirachta indica A.Juss), Escherichia coli, Staphylococcus aureus.
Bridging the Mind and Body
Authors: Shumaker Jasmine , Yohannes Semhar , Sannella Lydia
Published: January 2024

Academic libraries and campus food pantries are on the front lines of feeding college students experiencing food insecurity.  Academic libraries are uniquely positioned to address these students. Food pantries located in academic libraries have many advantages over traditional food pantries, such as longer hours, greater accessibility, and staff with more customer service experience.

This paper will focus on the budding partnership between the University of Maryland, Baltimore County’s Albin O. Kuhn Library and Retriever Essentials, the on-campus food access initiative. We will examine the campus demographics, specifically campus food insecurity statistics, and how that contributes to the overall need for the Library mini pantry space. In addition, we will also discuss ways to identify key partners, the ideal location, and the best pantry model to implement. 

The urgency of this initiative encourages us to include “tips to getting started” at your own campus. Usage statistics will also be briefed, and best practices, including the need to include culturally inclusive foods, will be reviewed as well as our next steps for the mini pantry.
Grassroots Inquiry through Reading Groups in Academic Libraries
Authors: Kuecker Elliott , McGinn Emily
Published: January 2024

Reading groups organized within academic libraries offer an interdisciplinary/undisciplined space for academics to discuss scholarly readings without the typical expectations associated with reading within the academy. Unlike reading for coursework or in order to write, which positoins the reader as a suspicious critic, reading as a community interested in a shared topic of inquiry opens up new avenues for interpretation and collaboration. This article describes some history of reading groups, how they are related to libraries, and theories of reading that help explore why reading groups create a sense of grassroots inquiry. It also offers practical advice for those interested in creating academic reading groups in their library.
Cardiovascular Comorbidities in COVID-19: Comprehensive Analysis of Key Topics (Preprint)
Authors: Markovič Rene , Ternar Luka , Trstenjak Tim , Marhl Marko , Grubelnik Vladimir
Published: January 2024

BACKGROUND

The interrelation between COVID-19 and various cardiovascular and metabolic disorders has been a critical area of study. There is a growing need to understand how comorbidities such as cardiovascular diseases (CVDs) and metabolic disorders affect the risk and severity of COVID-19.

OBJECTIVE

The objective of this study is to systematically analyze the association between COVID-19 and cardiovascular and metabolic disorders. The focus is on comorbidity, examining the roles of CVDs such as embolism, thrombosis, hypertension, and heart failure, as well as metabolic disorders such as disorders of glucose and iron metabolism.

METHODS

Our study involved a systematic search in PubMed for literature published from 2000 to 2022. We established 2 databases: one for COVID-19–related articles and another for CVD-related articles, ensuring all were peer-reviewed. In terms of data analysis, statistical methods were applied to compare the frequency and relevance of MeSH (Medical Subject Headings) terms between the 2 databases. This involved analyzing the differences and ratios in the usage of these terms and employing statistical tests to determine their significance in relation to key CVDs within the COVID-19 research context.

RESULTS

The study revealed that “Cardiovascular Diseases” and “Nutritional and Metabolic Diseases” were highly relevant as level 1 Medical Subject Headings descriptors in COVID-19 comorbidity research. Detailed analysis at level 2 and level 3 showed “Vascular Disease” and “Heart Disease” as prominent descriptors under CVDs. Significantly, “Glucose Metabolism Disorders” were frequently associated with COVID-19 comorbidities such as embolism, thrombosis, and heart failure. Furthermore, iron deficiency (ID) was notably different in its occurrence between COVID-19 and CVD articles, underlining its significance in the context of COVID-19 comorbidities. Statistical analysis underscored these differences, highlighting the importance of both glucose and iron metabolism disorders in COVID-19 research.

CONCLUSIONS

This work lays the foundation for future research that utilizes a knowledge-based approach to elucidate the intricate relationships between these conditions, aiming to develop more effective health care strategies and interventions in the face of ongoing pandemic challenges.
Effects of mobile health intervention based on behavioral integrated model on cognitive and behavioral changes in gestational weight management: Randomized controlled trial (Preprint)
Authors: You Hua , Zhou Meng , Wang Li , Ge Jinjin , Zhao Shiqi
Published: January 2024

BACKGROUND

The key to gestational weight management intervention involves health-related behaviors, including dietary and exercise management. Behavioral theory-based interventions are effective in improving health-related behaviors. However, evidence for mobile health interventions based on specific behavioral theories is insufficient and their effects have not been fully elucidated.

OBJECTIVE

To examine the effects of gestational mobile health intervention on psychological cognition and behavior for gestational weight management, using an integrated behavioral model as the theoretical framework.

METHODS

This study was conducted in Tertiary maternity hospital and conducted as a single-blind randomized controlled trial (RCT) in Changzhou, Jiangsu Province, China. Using the behavioral model, integrated with the protection motivation theory and information–motivation–behavioral skills model (PMT-IMB model), the intervention group received mobile health intervention using a self-developed app from 14 to 37 gestational weeks, whereas the control group received routine guidance. Psychological cognition and behaviors related to weight management during pregnancy were main outcomes, which measured at baseline, and at second and third trimesters of pregnancy using a self-designed questionnaire. Generalized estimation and regression equations were used to compare the outcome differences between the intervention and control groups.

RESULTS

In total, 302 participants (83.9%) underwent all measurements at three time points (intervention group: 150, control group: 152). Compared with the control group, the intervention group had significantly higher scores for information, perceived vulnerability, response cost, and exercise management in the second trimester, while their scores for perceived vulnerability, response cost, and diet management were significantly higher in the third trimester. Repeated measurement analysis results revealed that the time and group effects on information and response cost were statistically significant for psychological cognition, while only group effects were detected for perceived vulnerability (adjusted B=0.669, 95% CI: 0.050–1.288, p = 0.034). Moreover, the time and group effects on exercise management and total points were statistically significant for weight management behavior.

CONCLUSIONS

The intervention program was effective in increasing psychological cognitions and healthy behaviors among Chinese pregnant women. This study provides new evidence supporting the effectiveness of mobile intervention based on behavioral science theory in gestational weight management.

CLINICALTRIAL

Chinese Clinical Trial Registration Center (ChiCTR2100043231)
Leveraging Large Language Models for Improved Patient Access and Self-Management: Assessor-Blinded Comparison Between Expert- and AI-Generated Content (Preprint)
Authors: Lv Xiaolei , Zhang Xiaomeng , Li Yuan , Ding Xinxin , Lai Hongchang , Shi Junyu
Published: January 2024

BACKGROUND

While large language models (LLMs) such as ChatGPT and Google Bard have shown significant promise in various fields, their broader impact on enhancing patient health care access and quality, particularly in specialized domains such as oral health, requires comprehensive evaluation.

OBJECTIVE

This study aims to assess the effectiveness of Google Bard, ChatGPT-3.5, and ChatGPT-4 in offering recommendations for common oral health issues, benchmarked against responses from human dental experts.

METHODS

This comparative analysis used 40 questions derived from patient surveys on prevalent oral diseases, which were executed in a simulated clinical environment. Responses, obtained from both human experts and LLMs, were subject to a blinded evaluation process by experienced dentists and lay users, focusing on readability, appropriateness, harmlessness, comprehensiveness, intent capture, and helpfulness. Additionally, the stability of artificial intelligence responses was also assessed by submitting each question 3 times under consistent conditions.

RESULTS

Google Bard excelled in readability but lagged in appropriateness when compared to human experts (mean 8.51, SD 0.37 vs mean 9.60, SD 0.33; P=.03). ChatGPT-3.5 and ChatGPT-4, however, performed comparably with human experts in terms of appropriateness (mean 8.96, SD 0.35 and mean 9.34, SD 0.47, respectively), with ChatGPT-4 demonstrating the highest stability and reliability. Furthermore, all 3 LLMs received superior harmlessness scores comparable to human experts, with lay users finding minimal differences in helpfulness and intent capture between the artificial intelligence models and human responses.

CONCLUSIONS

LLMs, particularly ChatGPT-4, show potential in oral health care, providing patient-centric information for enhancing patient education and clinical care. The observed performance variations underscore the need for ongoing refinement and ethical considerations in health care settings. Future research focuses on developing strategies for the safe integration of LLMs in health care settings.