bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure S3 from Parallel Signaling through IRE1α and PERK Regulates Pancreatic Neuroendocrine Tumor Growth and Survival
Authors: Moore Paul C. , Qi Jenny Y. , Thamsen Maike , Ghosh Rajarshi , Peng Justin , Gliedt Micah J. , Meza-Acevedo Rosa , Warren Rachel E. , Hiniker Annie , Kim Grace E. , Maly Dustin J. , Backes Bradley J. , Papa Feroz R. , Oakes Scott A.
Published: April 2023

Scrambled CRISPR controls do not decrease INS1 tumor burden
Supplementary Data from Curatopes Melanoma: A Database of Predicted T-cell Epitopes from Overly Expressed Proteins in Metastatic Cutaneous Melanoma
Authors: Lischer Christopher , Eberhardt Martin , Jaitly Tanushree , Schinzel Cornelia , Schaft Niels , Dörrie Jan , Schuler Gerold , Vera Julio
Published: April 2023

Contains further information on raw data, its sources and processing (NGS pipeline, tissue lists and selection). We also provide supporting information on the selected genes and their expression patterns in the relevant tissues.
Supplementary Figure 1 from Macrophage-Derived IL1β and TNFα Regulate Arginine Metabolism in Neuroblastoma
Authors: Fultang Livingstone , Gamble Laura D. , Gneo Luciana , Berry Andrea M. , Egan Sharon A. , De Bie Fenna , Yogev Orli , Eden Georgina L. , Booth Sarah , Brownhill Samantha , Vardon Ashley , McConville Carmel M. , Cheng Paul N. , Norris Murray D. , Etchevers Heather C. , Murray Jayne , Ziegler David S. , Chesler Louis , Schmidt Ronny , Burchill Susan A. , Haber Michelle , De Santo Carmela , Mussai Francis
Published: April 2023

Supplementary Figure 1: M1-Macrophage infiltrate neuroblastoma
Table S1 from Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway
Authors: Xia Yingfeng , Ye Bingwei , Ding Jane , Yu Yajie , Alptekin Ahmet , Thangaraju Muthusamy , Prasad Puttur D. , Ding Zhi-Chun , Park Eun Jeong , Choi Jeong-Hyeon , Gao Bei , Fiehn Oliver , Yan Chunhong , Dong Zheng , Zha Yunhong , Ding Han-Fei
Published: April 2023

List of genes regulated by the PHGDH inhibitor NCT-503
Supplementary Data from Metabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway
Authors: Xia Yingfeng , Ye Bingwei , Ding Jane , Yu Yajie , Alptekin Ahmet , Thangaraju Muthusamy , Prasad Puttur D. , Ding Zhi-Chun , Park Eun Jeong , Choi Jeong-Hyeon , Gao Bei , Fiehn Oliver , Yan Chunhong , Dong Zheng , Zha Yunhong , Ding Han-Fei
Published: April 2023

Supplementary Figures: SF1, MYCN amplification vs SGOC gene expression; SF2, MYCN activates SGOC gene expression; SF3, ATF4 activates SGOC gene expression; SF4, MYCN and ATF4 form a positive feedback loop; SF5, MYCN sensitizes neuroblastoma cells to PHGDH inhibition; SF6, PHGDH inhibition induces metabolic stress response. Supplementary Materials and Methods
Supplementary Data S1-S5, Table from Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
Authors: Morcelle Carmen , Menoyo Sandra , Morón-Duran Francisco D. , Tauler Albert , Kozma Sara C. , Thomas George , Gentilella Antonio
Published: April 2023

Supplementary experiments demonstrate that equivalent results to those obtained in RKO cells are also obtained in HCT 116 cells, that the RPL5 antibody precipitation of the IRBC complex is specific and that ribosome biogenesis is upregulated in MYC induced cells.
Figure S2 from S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma
Authors: Xiao Yiren , Zhao Hongjuan , Tian Lei , Nolley Rosalie , Diep Anh N. , Ernst Anne , Fuh Katherine C. , Miao Yu Rebecca , von Eyben Rie , Leppert John T. , Brooks James D. , Peehl Donna M. , Giaccia Amato J. , Rankin Erinn B.
Published: April 2023

S100A10 and ANXA2 expression in ccRCC.
Supplementary Text from Toward Personalized Computer Simulation of Breast Cancer Treatment: A Multiscale Pharmacokinetic and Pharmacodynamic Model Informed by Multitype Patient Data
Authors: Lai Xiaoran , Geier Oliver M. , Fleischer Thomas , Garred Øystein , Borgen Elin , Funke Simon W. , Kumar Surendra , Rognes Marie E. , Seierstad Therese , Børresen-Dale Anne-Lise , Kristensen Vessela N. , Engebraaten Olav , Köhn-Luque Alvaro , Frigessi Arnoldo
Published: April 2023

Supplementary text to the main article detailing mathematical model, model initialisation and parametrisation, computational details and overview of clinical data .
Figure S8 from The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11
Authors: Liu Tong , Jiang Le , Tavana Omid , Gu Wei
Published: April 2023

SLC7A11 interacts with the standard form of CD44
Figure S5 from The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11
Authors: Liu Tong , Jiang Le , Tavana Omid , Gu Wei
Published: April 2023

OTUB1 is overexpressed in human cancers
Supplementary Data from Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc− Activity
Authors: McCormick Patrick N. , Greenwood Hannah E. , Glaser Matthias , Maddocks Oliver D.K. , Gendron Thibault , Sander Kerstin , Gowrishankar Gayatri , Hoehne Aileen , Zhang Tong , Shuhendler Adam J. , Lewis David Y. , Berndt Mathias , Koglin Norman , Lythgoe Mark F. , Gambhir Sanjiv S. , Årstad Erik , Witney Timothy H.
Published: April 2023

Supplementary Methods and Figures 1 - 6. Fig. S1 shows effect of TBHP treatment on ROS and [18F]FSPG uptake in ovarian cancer cell lines; Fig. S2 illustrates the relationship between glutamate and cystine concentrations on [18F]FSPG uptake; Fig. S3 quantifies [U-13C6, U-15N2]cystine labeling of M+8 GSSG; Fig. S4 indicates extensive disulfide exchange between cystine and NAC; Fig. S5 depicts doxorubicin-mediated alterations in tumor cell redox state and [18F]FSPG; and Fig. S6 illustrates changes in [18F]FSPG and [18F]FDG tumor retention after doxil treatment of mice.
Figure S1 from Radiation Drives the Evolution of Orthotopic Xenografts Initiated from Glioblastoma Stem–like Cells
Authors: McAbee Joseph H. , Rath Barbara H. , Valdez Kristin , Young Dejauwne L. , Wu Xiaolin , Shankavaram Uma T. , Camphausen Kevin , Tofilon Philip J.
Published: April 2023

higher magnification of xenograft histology
Figure S3 from DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs
Authors: Oshima Go , Poli Elizabeth C. , Bolt Michael J. , Chlenski Alexandre , Forde Martin , Jutzy Jessica M.S. , Biyani Neha , Posner Mitchell C. , Pitroda Sean P. , Weichselbaum Ralph R. , Khodarev Nikolai N.
Published: April 2023

Failure of DNMT 1/3B double-knockout cells to produce liver metastases.
Figure S1-S2 from DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs
Authors: Oshima Go , Poli Elizabeth C. , Bolt Michael J. , Chlenski Alexandre , Forde Martin , Jutzy Jessica M.S. , Biyani Neha , Posner Mitchell C. , Pitroda Sean P. , Weichselbaum Ralph R. , Khodarev Nikolai N.
Published: April 2023

Plasmid map of CRISPR vector and deletion schematic for CFdel cells
Supplementary Data from Time-Resolved MRI Assessment of Convection-Enhanced Delivery by Targeted and Nontargeted Nanoparticles in a Human Glioblastoma Mouse Model
Authors: Stephen Zachary R. , Chiarelli Peter A. , Revia Richard A. , Wang Kui , Kievit Forrest , Dayringer Chris , Jeon Mike , Ellenbogen Richard , Zhang Miqin
Published: April 2023

Supplementary Figure S1 provides a representative TEM image of NPCP-CTX and corresponding histogram presenting the core diameter distribution.
Table S5 from Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells
Authors: Erber Johanna , Steiner Joachim D. , Isensee Jörg , Lobbes Leonard A. , Toschka André , Beleggia Filippo , Schmitt Anna , Kaiser Rainer W. J. , Siedek Florian , Persigehl Thorsten , Hucho Tim , Reinhardt Hans C.
Published: April 2023

Table S5 contains data of the GSEA analysis.
Supplementary Data from Time-Resolved MRI Assessment of Convection-Enhanced Delivery by Targeted and Nontargeted Nanoparticles in a Human Glioblastoma Mouse Model
Authors: Stephen Zachary R. , Chiarelli Peter A. , Revia Richard A. , Wang Kui , Kievit Forrest , Dayringer Chris , Jeon Mike , Ellenbogen Richard , Zhang Miqin
Published: April 2023

Supplementary Figure S2 provides Volume of distribution data for a syngeneic GL261 glioma model.
Supplementary Data from Immuno-oncological Efficacy of RXDX-106, a Novel TAM (TYRO3, AXL, MER) Family Small-Molecule Kinase Inhibitor
Authors: Yokoyama Yumi , Lew Erin D. , Seelige Ruth , Tindall Elizabeth A. , Walsh Colin , Fagan Patrick C. , Lee Jack Y. , Nevarez Robin , Oh Joanne , Tucker Kathleen D. , Chen Marissa , Diliberto Amy , Vaaler Heather , Smith Kristen M. , Albert Amanda , Li Gary , Bui Jack D.
Published: April 2023

Included are additional material and methods, biochemical and functional data demonstrating target specificity and engagement, flow cytometry gating strategies, histograms, and analyses, and TME cytokine data.
Supplementary Figure S1 from Loss of E-Cadherin Inhibits CD103 Antitumor Activity and Reduces Checkpoint Blockade Responsiveness in Melanoma
Authors: Shields Bradley D. , Koss Brian , Taylor Erin M. , Storey Aaron J. , West Kirk L. , Byrum Stephanie D. , Mackintosh Samuel G. , Edmondson Rick , Mahmoud Fade , Shalin Sara C. , Tackett Alan J.
Published: April 2023

Figure S1- B16.Ecad and B16.Vector lung metastases in Rag 1-/- mice
Supplementary Table S1 from BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents
Authors: Kanakkanthara Arun , Kurmi Kiran , Ekstrom Thomas L. , Hou Xiaonan , Purfeerst Emma R. , Heinzen Ethan P. , Correia Cristina , Huntoon Catherine J. , O'Brien Daniel , Wahner Hendrickson Andrea E. , Dowdy Sean C. , Li Hu , Oberg Ann L. , Hitosugi Taro , Kaufmann Scott H. , Weroha S. John , Karnitz Larry M.
Published: April 2023

Excel data file of RNA-seq from OVCAR-8 cells transfected with luciferase vs CDK12 siRNAs.
Figure S19 from Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
Authors: Housley Stephen N. , Nardelli Paul , Carrasco Dario I. , Rotterman Travis M. , Pfahl Emily , Matyunina Lilya V. , McDonald John F. , Cope Timothy C.
Published: April 2023

LD1 analysis of all neuronal parameters
Figure S13 from Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
Authors: Housley Stephen N. , Nardelli Paul , Carrasco Dario I. , Rotterman Travis M. , Pfahl Emily , Matyunina Lilya V. , McDonald John F. , Cope Timothy C.
Published: April 2023

ASIC2 immunostaining of proprioceptive sensory neurons receptor endings
Figure S12 from Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
Authors: Housley Stephen N. , Nardelli Paul , Carrasco Dario I. , Rotterman Travis M. , Pfahl Emily , Matyunina Lilya V. , McDonald John F. , Cope Timothy C.
Published: April 2023

Nav1.6 immunostaining of proprioceptive sensory neurons receptor endings
Supplementary Data from Adhesion of T Cells to Endothelial Cells Facilitates Blinatumomab-Associated Neurologic Adverse Events
Authors: Klinger Matthias , Zugmaier Gerhard , Nägele Virginie , Goebeler Maria-Elisabeth , Brandl Christian , Stelljes Matthias , Lassmann Hans , von Stackelberg Arend , Bargou Ralf C. , Kufer Peter
Published: April 2023

Table S1. Designs, primary results, and incidences of neurologic adverse events of the five clinical studies with blinatumomab of which data was used in present analysis; Table S2: Multivariate analyses of blinatumomab-treated patients with r/r NHL or r/r ALL.
Supplementary Table 3 from IL26, a Noncanonical Mediator of DNA Inflammatory Stimulation, Promotes TNBC Engraftment and Progression in Association with Neutrophils
Authors: Trotter Timothy N. , Shuptrine Casey W. , Tsao Li-Chung , Marek Robert D. , Acharya Chaitanya , Wei Jun-Ping , Yang Xiao-Yi , Lei Gangjun , Wang Tao , Lyerly Herbert Kim , Hartman Zachary C.
Published: April 2023

List of significant gene symbols
Supplementary Data from MYC Drives Group 3 Medulloblastoma through Transformation of Sox2+ Astrocyte Progenitor Cells
Authors: Tao Ran , Murad Najiba , Xu Zhenhua , Zhang Peng , Okonechnikov Konstantin , Kool Marcel , Rivero-Hinojosa Samuel , Lazarski Christopher , Zheng Pan , Liu Yang , Eberhart Charles G. , Rood Brian R. , Packer Roger , Pei Yanxin
Published: April 2023

Figure S1 shows MYC driven tumors generated from early postnatal cerebellar cells. Figure S2 shows IHC staining of tdt+ or tdt- MYC-driven tumors. Figure S3 shows gene expression of mouse MYC-driven tumors compared to that of human medulloblastomas. Figure S4 shows properties of Sox2+/Aldh1L1high, Sox2+/Aldh1L1low and Sox2+/Aldh1L1neg cells. Figure S5 shows properties of Sox2+/CD133+, Sox2+/CD133- or Sox2-/CD133+ cells. Figure S6 shows gene expression of SOX family members in tumors or normal cerebellar cells. Figure S7 shows that LDHA is a potential target for treating human MYC-amplified medulloblastoma.
Supplementary Data from Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma
Authors: Abdul Pari Ashik Ahmed , Singhal Mahak , Hübers Corinne , Mogler Carolin , Schieb Benjamin , Gampp Anja , Gengenbacher Nicolas , Reynolds Louise E. , Terhardt Dorothee , Géraud Cyrill , Utikal Jochen , Thomas Markus , Goerdt Sergij , Hodivala-Dilke Kairbaan M. , Augustin Hellmut G. , Felcht Moritz
Published: April 2023

This file consists of supplementary figures (SF) 1-11 consisting of: SF1: Melanoma cells express ANGPT2 (A-F). SF2: Melanoma cell-expressed Angpt2 does not modulate tumor cell proliferation (A-B). SF3: Tumor cell knockdown of Angpt2 does not impact growth of primary tumors (A-J). SF4: Angpt2-depletion in melanoma cells does not affect primary tumor microenvironment (A-F). SF5: Angpt2-depletion alters pathways governing metastasis and oxidative stress (A-B). SF6: Angpt2 knockdown in tumor cells affects the cellular redox balance (A-G). SF7: Tumor cell-expressed Angpt2 alters mitochondrial dynamics (A-E). SF8: Tumor cell-expressed Angpt2 promotes metastasis (A-G). SF9: Tumor cell-expressed Angpt2 does not affect early stages of metastasis in vitro (A-H). SF10: Silencing of Angpt2 impairs invasion through the basement membrane and transmigration across the endothelial barrier (A-H). SF11: Silencing of Angpt2 reduces in vitro colony formation (A-F).
Supplementary Data from Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
Authors: Henderson Fiona , Johnston Hannah R. , Badrock Andrew P. , Jones Emrys A. , Forster Duncan , Nagaraju Raghavendar T. , Evangelou Christos , Kamarashev Jivko , Green Michael , Fairclough Michael , Ramirez Irene Barinaga-Rementeria , He Shuning , Snaar-Jagalska B. Ewa , Hollywood Katherine , Dunn Warwick B. , Spaink Herman P. , Smith Michael P. , Lorigan Paul , Claude Emmanuelle , Williams Kaye J. , McMahon Adam W. , Hurlstone Adam
Published: April 2023

Figures S1-S9
Tables S3-S8 from Transcriptomics Associates Molecular Features with 18F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma
Authors: Kwee Sandi A. , Tiirikainen Maarit , Sato Miles M. , Acoba Jared D. , Wei Runmin , Jia Wei , Le Marchand Loic , Wong Linda L.
Published: April 2023

Gene set overlap analysis results
Table S1 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

Pathway analysis after intersection of DNA methylation and RNAseq
Table S1 from Transcriptomics Associates Molecular Features with 18F-Fluorocholine PET/CT Imaging Phenotype and Its Potential Relationship to Survival in Hepatocellular Carcinoma
Authors: Kwee Sandi A. , Tiirikainen Maarit , Sato Miles M. , Acoba Jared D. , Wei Runmin , Jia Wei , Le Marchand Loic , Wong Linda L.
Published: April 2023

Functional Annotation Cluster Results
Figure S7 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

Effect of preoperative COX2 inhibition in combination with IL-6 neutralization on metastasis, recurrent tumor, and CTCs
Figure S4 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

Pathways and biology functions targeted by DNMT3B in cancer metastasis
Figure S3 from Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
Authors: So Jae Young , Skrypek Nicolas , Yang Howard H. , Merchant Anand S. , Nelson George W. , Chen Wei-Dong , Ishii Hiroki , Chen Jennifer M. , Hu Gangqing , Achyut Bhagelu R. , Yoon Esther C. , Han Liying , Huang Chuanshu , Cam Margaret C. , Zhao Keji , Lee Maxwell P. , Yang Li
Published: April 2023

DNMT3B targeted molecules and pathways comparing MFP-met with primary tumors
Supplementary Figures from Prostaglandin E1 Inhibits GLI2 Amplification–Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth
Authors: Wu Fujia , Zhang Chenze , Zhao Chen , Wu Hao , Teng Zhaoqian , Jiang Tao , Wang Yu
Published: April 2023

Supplementary Figure S1. Generation and characterization of cell lines for high content screening and GLI-luciferase reporter assays. Supplementary Figure S2. A high content screening identifies compound candidates that inhibit GLI2 ciliary localization. Supplementary Figure S3. Additional prostaglandins were examined in the GLI-luciferase reporter assay using 3T3/GLI-luc/GLI2 cells. Supplementary Figure S4. Comparative examination of dose-dependent effects of the prostaglandins identified from high content screening on the GLI-luciferase reporter activity mediated by SMO-WT, SMO-D473H and SMO-W535L respectively. Supplementary Figure S5. Examination of prostaglandins against SHH-N/SAG-induced HH pathway activity. Supplementary Figure S6. A CRE-luciferase reporter assay was used to examine cAMP-PKA levels. Supplementary Figure S7. Generation and examination of EP4 knockout monoclonal cell lines. Supplementary Figure S8. Examination of the expression of EP receptors and the activity of PGE1 in DAOY cells and growth comparison of wild-type DAOY cells and GLI2-overexpressed DAOY cells. Supplementary Figure S9. Molecular analyses of Med-113FH and Med-314FH xenografts. Supplementary Figure S10. Examination of the activities of PGE1 metabolites. Supplementary Figure S11. Examination of additional clinical prostaglandins.
Supplemental figure 6 from Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy
Authors: Santana-Magal Nadine , Farhat-Younis Leen , Gutwillig Amit , Gleiberman Annette , Rasoulouniriana Diana , Tal Lior , Netanely Dvir , Shamir Ron , Blau Rachel , Feinmesser Meora , Zlotnik Oran , Gutman Haim , Linde Ian L. , Reticker-Flynn Nathan E. , Rider Peleg , Carmi Yaron
Published: April 2023

Proteins associated with myeloid dendritic cells positively correlate with improved survival of melanoma patients
Supplemental figure 5 from Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy
Authors: Santana-Magal Nadine , Farhat-Younis Leen , Gutwillig Amit , Gleiberman Annette , Rasoulouniriana Diana , Tal Lior , Netanely Dvir , Shamir Ron , Blau Rachel , Feinmesser Meora , Zlotnik Oran , Gutman Haim , Linde Ian L. , Reticker-Flynn Nathan E. , Rider Peleg , Carmi Yaron
Published: April 2023

Tumor-infiltrating dendritic cells promote, in a contact-dependant manner, secretion of lytic granules by CD8+ T cells.
Supplementary Figure S6 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Characterization of SCH-resistant, N-Ras mutant melanoma cells
Supplementary Figure S3 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Analysis of IGF-1R mRNA expression and 3D spheroid growth assays in parental and SCH-resistant cells
Supplementary Figure S2 from Resistance to MAPK Inhibitors in Melanoma Involves Activation of the IGF1R–MEK5–Erk5 Pathway
Authors: Benito-Jardón Lucía , Díaz-Martínez Marta , Arellano-Sánchez Nohemi , Vaquero-Morales Paloma , Esparís-Ogando Azucena , Teixidó Joaquin
Published: April 2023

Phospho-receptor tyrosine kinase arrays and effect of lapatinib and trastuzumab in cell resistance to SCH
Supplementary Data from Genome-Wide RNAi Screen Identifies PMPCB as a Therapeutic Vulnerability in EpCAM+ Hepatocellular Carcinoma
Authors: Takai Atsushi , Dang Hien , Oishi Naoki , Khatib Subreen , Martin Sean P. , Dominguez Dana A. , Luo Ji , Bagni Rachel , Wu Xiaolin , Powell Katie , Ye Qing-Hai , Jia Hu-Liang , Qin Lun-Xiu , Chen Jinqiu , Mitchell Gary A. , Luo Xiaoling , Thorgeirsson Snorri S. , Wang Xin Wei
Published: April 2023

Supplementary Experimental Methods, References and Figure Legends.
Table S2 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Table S2. Image features that are significantly associated with patient overall survival outcome in univariate survival analysis in the National Lung Screening Trial (NLST) dataset. Features are dichotomized by the median value. P values are calculated using Ward test. CI, confidence interval; HR, hazard ratio.
Figure S9 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S9 Example of gene set enrichment analysis (GSEA) result correlating mRNA expression with image-derived stroma cell number and lymphocyte number, while patient IDs are randomly shuffled twice.
Figure S7 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S7 Illustration of Delaunay triangle construction.
Figure S6 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S6. Validation of macrophage detection results in whole-slide image nuclei segmentation and classification by HD-Staining model.
Figure S4 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S4 Whole-slide image nuclei segmentation and classification by HD-Staining model.
Figure S3 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S3 Confusion matrix between true labels and predicted labels, in 5 major lung adenocarcinoma subtypes respectively.
Figure S1 from Computational Staining of Pathology Images to Study the Tumor Microenvironment in Lung Cancer
Authors: Wang Shidan , Rong Ruichen , Yang Donghan M. , Fujimoto Junya , Yan Shirley , Cai Ling , Yang Lin , Luo Danni , Behrens Carmen , Parra Edwin R. , Yao Bo , Xu Lin , Wang Tao , Zhan Xiaowei , Wistuba Ignacio I. , Minna John , Xie Yang , Xiao Guanghua
Published: April 2023

Supplemental Figure S1 Illustration of 100 patches extraction from the Region of Interest (ROI) circled by pathologists.
Figure S6 from BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1
Authors: Zong Dan , Gu Jiajia , Cavalcante Giovanna C. , Yao Weilong , Zhang Guojing , Wang Shaomeng , Owonikoko Taofeek K. , He Xia , Sun Shi-Yong
Published: April 2023

ZBC260 and dBET at low concentration ranges do not synergize with TRAIL in decreasing the survival of H460 cells, but do so at high concentration ranges, likely due to the inability to decrease c-FLIP and Mcl-1 at low concentrations
Supplementary Figures from Genome-Wide Screening and Functional Analysis Identifies Tumor Suppressor Long Noncoding RNAs Epigenetically Silenced in Hepatocellular Carcinoma
Authors: Xu Feiyue , Li Chi Han , Wong Chi Hin , Chen George G. , Lai Paul Bo San , Shao Shengwen , Chan Stephen L. , Chen Yangchao
Published: April 2023

Supplementary Figure 1. Validation of the lncRNA microarray data using qRT-PCR. Supplementary Figure 2. Expression levels of DZnep-induced lncRNAs in a panel of HCC cell lines and non-tumor cell lines. Supplementary Figure 3. Expression levels of DZnep-induced lncRNAs in paired human HCC tissues and adjacent non-tumor tissues. Supplementary Figure 4. High specificity of ChIP assay in measuring true interaction between EZH2 and the promoters of EZH2 targeted genes. Supplementary Figure 5. Inhibition of TCAM1P-004 and RP11-598D14.1 with siRNAs promoted cell proliferation. Supplementary Figure 6. Knockdown of TCAM1P-004 and RP11-598D14.1 with shRNAs inhibited cell apoptosis, promoted colony formation ability and transformation ability, and stimulated tumor growth in xenograft mice model. Supplementary Figure 7. Overexpression of TCAM1P-004 and RP11-598D14.1 repressed cell colony formation and transformation abilities, and tumor growth in xenograft mice model. Supplementary Figure 8. Overexpression of TCAM1P-004 or RP11-598D14.1 promoted apoptosis in subcutaneous tumors derived from Hep3B cells. Supplementary Figure 9. Inhibition of TCAM1P-004 or RP11-598D14.1 could induce tumorigenesis of non-tumor MIHA cells. Supplementary Figure 10. KEGG pathway enrichment analysis of TCAM1P-004 and RP11-598D14.1 regulated genes. Supplementary Figure 11. qRT-PCR validated signaling pathways related to TCAM1P-004 and RP11-598D14.1. Supplementary Figure 12. Expression of DDIT and PFKFB4 in HCC cell lines and HCC tumor samples. Supplementary Figure 13. Expression of PFKFB4 in HCC tumor samples. Supplementary Figure 14. Alignment analysis between lncRNA TCAM1P-004 and RP11-598D14.1. Supplementary Figure 15. EZH1 showed no significant role in HCC.
Supplementary Data from Genome-Wide Screening and Functional Analysis Identifies Tumor Suppressor Long Noncoding RNAs Epigenetically Silenced in Hepatocellular Carcinoma
Authors: Xu Feiyue , Li Chi Han , Wong Chi Hin , Chen George G. , Lai Paul Bo San , Shao Shengwen , Chan Stephen L. , Chen Yangchao
Published: April 2023

Supplementary Figure Legends
Supplementary Table 6 from Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma
Authors: Atkins Isabelle , Kinnersley Ben , Ostrom Quinn T. , Labreche Karim , Il'yasova Dora , Armstrong Georgina N. , Eckel-Passow Jeanette E. , Schoemaker Minouk J. , Nöthen Markus M. , Barnholtz-Sloan Jill S. , Swerdlow Anthony J. , Simon Matthias , Rajaraman Preetha , Chanock Stephen J. , Shildkraut Joellen , Bernstein Jonine L. , Hoffmann Per , Jöckel Karl-Heinz , Lai Rose K. , Claus Elizabeth B. , Olson Sara H. , Johansen Christoffer , Wrensch Margaret R. , Melin Beatrice , Jenkins Robert B. , Sanson Marc , Bondy Melissa L. , Houlston Richard S.
Published: April 2023

Supplementary Table 6: Genes and their TWAS P-values for association with (a) GBM glioma (b) non-GBM glioma. s.d., standard deviation. Detailed are the S-MultiXcan P-value for association between gene expression and GBM/non-GBM risk and the corresponding Z-scores quantifying this relationship (e.g. a positive score indicates increased gene expression increases risk of GBM or non-GBM glioma). N and Nindep indicate the total number of single-tissue results used for S-MultiXcan analysis and the number of independent components after singular value decomposition, respectively. "p_i_best" and "t_i_best" correspond to the best single-tissue P-value and tissue model respectively, accordingly "p_i_worst" and "t_i_worset" correspond to the worst. "eigen_max" and "eigen_min" correspond to the maximum and minimum eigenvalue in the covariance matrix respectively, with "eigen_min_kept" corresponding to the minimum eigenvalue that survived thresholding.
Supplementary Table 5 from Transcriptome-Wide Association Study Identifies New Candidate Susceptibility Genes for Glioma
Authors: Atkins Isabelle , Kinnersley Ben , Ostrom Quinn T. , Labreche Karim , Il'yasova Dora , Armstrong Georgina N. , Eckel-Passow Jeanette E. , Schoemaker Minouk J. , Nöthen Markus M. , Barnholtz-Sloan Jill S. , Swerdlow Anthony J. , Simon Matthias , Rajaraman Preetha , Chanock Stephen J. , Shildkraut Joellen , Bernstein Jonine L. , Hoffmann Per , Jöckel Karl-Heinz , Lai Rose K. , Claus Elizabeth B. , Olson Sara H. , Johansen Christoffer , Wrensch Margaret R. , Melin Beatrice , Jenkins Robert B. , Sanson Marc , Bondy Melissa L. , Houlston Richard S.
Published: April 2023

Supplementary Table 5: Table of module color with module size and associated Z-statistics. Modules were created by clustering according to the Amygdala tissue using WGCNA11. These modules of gene number "moduleSize" were applied to each tissue in turn and the Z-statistic ("Zsummary.pres") is a quantitive measure of module preservation relative to Amygdala. (a) Anterior cingulate cortex (BA24); (b) Caudate (basal ganglia); (c) Cerebellar Hemisphere; (d) Cerebellum; (e) Cortex; (f) Frontal Cortex (BA9); (g) Hippocampus; (h) Hypothalamus; (i) Nucleus accumbens (basal ganglia); (j) Putamen (basal ganglia); (k) Spinal cord (cervical c-1); (l) Substantia nigra.
Figure S2 from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate
Authors: Xie Jianjiang , Ye Jianheng , Cai Zhiduan , Luo Yong , Zhu Xuejin , Deng Yulin , Feng Yuanfa , Liang Yingke , Liu Ren , Han Zhaodong , Liang Yuxiang , Zheng Yu , Mo Rujun , Zhuo Yangjia , Wu Yongding , Jiang Funeng , Zhu Jianguo , Wu Chin-Lee , Zhong Weide
Published: April 2023

Figure S2 showed the increased GPD1 expression was seen in cancer patients in TCGA database and GPD1 overexpression enhanced the anti-proliferation ability of metformin in vitro.
Figure S1 from GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate
Authors: Xie Jianjiang , Ye Jianheng , Cai Zhiduan , Luo Yong , Zhu Xuejin , Deng Yulin , Feng Yuanfa , Liang Yingke , Liu Ren , Han Zhaodong , Liang Yuxiang , Zheng Yu , Mo Rujun , Zhuo Yangjia , Wu Yongding , Jiang Funeng , Zhu Jianguo , Wu Chin-Lee , Zhong Weide
Published: April 2023

Figure S1 showed the expression of GPD1 and GPD2 in cells were determined by Western blot.
Figure S7 from A Versatile ES Cell–Based Melanoma Mouse Modeling Platform
Authors: Bok Ilah , Vera Olga , Xu Xiaonan , Jasani Neel , Nakamura Koji , Reff Jordan , Nenci Arianna , Gonzalez Jose G. , Karreth Florian A.
Published: April 2023

This Figure shows Pten restoration data obtained from an additional shPten cell line.
Figure S6 from A Versatile ES Cell–Based Melanoma Mouse Modeling Platform
Authors: Bok Ilah , Vera Olga , Xu Xiaonan , Jasani Neel , Nakamura Koji , Reff Jordan , Nenci Arianna , Gonzalez Jose G. , Karreth Florian A.
Published: April 2023

This Figure shows the testing of the functionality of the CHC, rtTA3, and Tyr-CreERt2 alleles in murine melanoma cell lines.
Figure S1 from A Versatile ES Cell–Based Melanoma Mouse Modeling Platform
Authors: Bok Ilah , Vera Olga , Xu Xiaonan , Jasani Neel , Nakamura Koji , Reff Jordan , Nenci Arianna , Gonzalez Jose G. , Karreth Florian A.
Published: April 2023

This Figure shows the appearance of melanomas as well as the survival and tumor number of the different chimera models.
Figure 2S from A Versatile ES Cell–Based Melanoma Mouse Modeling Platform
Authors: Bok Ilah , Vera Olga , Xu Xiaonan , Jasani Neel , Nakamura Koji , Reff Jordan , Nenci Arianna , Gonzalez Jose G. , Karreth Florian A.
Published: April 2023

This Figure shows the efficiency of Pten silencing using Cre/loxP, shRNA and CRISPR as well as chimera contribution of targeted ES cells.
Supplementary Data from Therapeutic Potential of the miRNA–ATM Axis in the Management of Tumor Radioresistance
Authors: Rezaeian Abdol-Hossein , Khanbabaei Hashem , Calin George A.
Published: April 2023

S Table 1
Supplementary Data from Y Chromosome LncRNA Are Involved in Radiation Response of Male Non–Small Cell Lung Cancer Cells
Authors: Brownmiller Tayvia , Juric Jamie A. , Ivey Abby D. , Harvey Brandon M. , Westemeier Emily S. , Winters Michael T. , Stevens Alyson M. , Stanley Alana N. , Hayes Karen E. , Sprowls Samuel A. , Ammer Amanda S. Gatesman , Walker Mackenzee , Bey Erik A. , Wu Xiaoliang , Lim Zuan-Fu , Zhu Lin , Wen Sijin , Hu Gangqing , Ma Patrick C. , Martinez Ivan
Published: April 2023

Table S1 to S4; Figures S1 to S12
Supplementary Data from Cellular Senescence Promotes Skin Carcinogenesis through p38MAPK and p44/42MAPK Signaling
Authors: Alimirah Fatouma , Pulido Tanya , Valdovinos Alexis , Alptekin Sena , Chang Emily , Jones Elijah , Diaz Diego A. , Flores Jose , Velarde Michael C. , Demaria Marco , Davalos Albert R. , Wiley Christopher D. , Limbad Chandani , Desprez Pierre-Yves , Campisi Judith
Published: April 2023

Supplementary Data supporting the manuscript.
Table S1, S2, S3 and S4; Figure S1, S2,and S3 from An Allosteric PRC2 Inhibitor Targeting EED Suppresses Tumor Progression by Modulating the Immune Response
Authors: Dong Hongping , Liu Shaojun , Zhang Xuejie , Chen Sheng , Kang Lijing , Chen Yanni , Ma Shichao , Fu Xianlei , Liu Yanchao , Zhang Hailong , Zou Bin
Published: April 2023

Data for article support. Supplementary Table 1. Antibody used for ELISA and WB; Supplementary Table 2. Primers used for quantitative Real-time RT-PCR; Supplementary Table 3. BR-A selectivity across a panel of kinases; Supplementary Table 4. EED-BR-001 Data collection and refinement statistics; Supplementary Figure 1. BR-001 decreases global H3K27 methylation. Inhibition of H3K27 methylation in cells treated with different concentrations of BR-001 was measured. KATO III and SNU16 cells were treated with BR-001 for 3 days at the indicated concentrations. Levels of H3K27me3 in cell lysate was detected using ELISA . All experiments were repeated three times and representative data are shown; Supplementary Figure 2. BR-001 suppress tumor growth in mouse xenograft and syngeneic models. Effect of BR-001 on body weight in Karpas422 xenograft (A), Pfeiffer xenograft (B) and murine CT26 models (C) (n=10). The data are shown as mean {plus minus} SEM; Supplementary Figure 3. Flow cytometry analysis of tumor-infiltrating lymphocytes (TILs). Counts of MDSCs (A), NK cells (B), TAMs (C) , CD45+ cells (D), CD3+ cells (E) and CD4+ cells (F) in fresh tumors collected at the last day of BR-001 dosing (Figure 4D, n=10). The data are shown as mean {plus minus} SEM
Table S4 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

Experimentally analyzed DLC1 mutants
Supplementary Tables from Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis
Authors: Singh Mohini , Venugopal Chitra , Tokar Tomas , McFarlane Nicole , Subapanditha Minomi K. , Qazi Maleeha , Bakhshinyan David , Vora Parvez , Murty Naresh K. , Jurisica Igor , Singh Sheila K.
Published: April 2023

Supplementary information depicting n numbers of in vivo experiments, primer sequences, and top drug hits.
Supplementary Figures from Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis
Authors: Singh Mohini , Venugopal Chitra , Tokar Tomas , McFarlane Nicole , Subapanditha Minomi K. , Qazi Maleeha , Bakhshinyan David , Vora Parvez , Murty Naresh K. , Jurisica Igor , Singh Sheila K.
Published: April 2023

Supplementary figures of additional heatmaps generated from the RNA sequencing analyses, snapshots of dysregulated BMIT genes within KEGG and GO datasets, and futher Apomorphine analyses.
Table S2 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

Summary for missense, nonsense, and frame-shift mutations of various tumor types
Table S1 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

RT-PCR primers for mutagenesis
Supplementary Dataset S2 from Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis
Authors: Singh Mohini , Venugopal Chitra , Tokar Tomas , McFarlane Nicole , Subapanditha Minomi K. , Qazi Maleeha , Bakhshinyan David , Vora Parvez , Murty Naresh K. , Jurisica Igor , Singh Sheila K.
Published: April 2023

Heatmaps depicting dysregulated BMIT genes in cellular processes
Figure S1-3 from Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
Authors: Wang Dunrui , Qian Xiaolan , Sanchez-Solana Beatriz , Tripathi Brajendra K. , Durkin Marian E. , Lowy Douglas R.
Published: April 2023

DLC1 and NF1 mutations in various tumor types
Figure S3 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

Knockdown of EphA2 and EphA3 alters cell cycle and increases apoptosis in recurrent GBM.
Supplementary Data from Cancer-Induced Muscle Wasting Requires p38β MAPK Activation of p300
Authors: Sin Thomas K. , Zhang Guohua , Zhang Zicheng , Zhu James Z. , Zuo Yan , Frost Jeffrey A. , Li Min , Li Yi-Ping
Published: April 2023

Supplementary figures
Figure S1 from Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma
Authors: Qazi Maleeha A. , Vora Parvez , Venugopal Chitra , Adams Jarrett , Singh Mohini , Hu Amy , Gorelik Maryna , Subapanditha Minomi K. , Savage Neil , Yang Jiahe , Chokshi Chirayu , London Max , Gont Alexander , Bobrowski David , Grinshtein Natalie , Brown Kevin R. , Murty Naresh K. , Nilvebrant Johan , Kaplan David , Moffat Jason , Sidhu Sachdev , Singh Sheila K.
Published: April 2023

Protein expression of EphA2, EphA3, CD133, CD15, Bmi1, Sox2, FoxG1 and ITGA6 in GBM.
TableS3 from FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy
Authors: Manfrini Nicola , Mancino Marilena , Miluzio Annarita , Oliveto Stefania , Balestra Matteo , Calamita Piera , Alfieri Roberta , Rossi Riccardo L. , Sassoè-Pognetto Marco , Salio Chiara , Cuomo Alessandro , Bonaldi Tiziana , Manfredi Marcello , Marengo Emilio , Ranzato Elia , Martinotti Simona , Cittaro Davide , Tonon Giovanni , Biffo Stefano
Published: April 2023

Proteomics of purified FAM46C/FNDC3A complex
Supplementary Methods from A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier
Authors: Hilfenhaus Georg , Mompeón Ana , Freshman Jonathan , Prajapati Divya P. , Hernandez Gloria , Freitas Vanessa M. , Ma Feiyang , Langenbacher Adam D. , Mirkov Snezana , Song Dana , Cho Byoung-Kyu , Goo Young Ah , Pellegrini Matteo , Chen Jau-Nian , Damoiseaux Robert , Iruela-Arispe M. Luisa
Published: April 2023

Methods and Reagents
Supplementary Figure 7 from A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier
Authors: Hilfenhaus Georg , Mompeón Ana , Freshman Jonathan , Prajapati Divya P. , Hernandez Gloria , Freitas Vanessa M. , Ma Feiyang , Langenbacher Adam D. , Mirkov Snezana , Song Dana , Cho Byoung-Kyu , Goo Young Ah , Pellegrini Matteo , Chen Jau-Nian , Damoiseaux Robert , Iruela-Arispe M. Luisa
Published: April 2023

Determination of niclosamide stability and approach for counting lung metastatic nodules
Supplementary Methods from A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents
Authors: Sapkota Yadav , Wilson Carmen L. , Zaidi Asifa K. , Moon Wonjong , Fon Tacer Klementina , Lu Lu , Liu Qi , Baedke Jessica , Dhaduk Rikeenkumar , Wang Zhaoming , Chemaitilly Wassim , Krasin Matthew J. , Berry Fred B. , Zhang Jinghui , Hudson Melissa M. , Robison Leslie L. , Green Daniel M. , Yasui Yutaka
Published: April 2023

Supplementary Methods
Supplementary Figure 3 from A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier
Authors: Hilfenhaus Georg , Mompeón Ana , Freshman Jonathan , Prajapati Divya P. , Hernandez Gloria , Freitas Vanessa M. , Ma Feiyang , Langenbacher Adam D. , Mirkov Snezana , Song Dana , Cho Byoung-Kyu , Goo Young Ah , Pellegrini Matteo , Chen Jau-Nian , Damoiseaux Robert , Iruela-Arispe M. Luisa
Published: April 2023

Effects of positive hits on endothelial barrier, cytoskeletal organization and tumor cell motility
Supplmentary text from Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting
Authors: Cheung Phyllis F. , Neff Florian , Neander Christian , Bazarna Anna , Savvatakis Konstantinos , Liffers Sven-Thorsten , Althoff Kristina , Lee Chang-Lung , Moding Everett J. , Kirsch David G , Saur Dieter , Bazhin Alexandr V. , Trajkovic-Arsic Marija , Heikenwalder Mathias F. , Siveke Jens T.
Published: April 2023

Supplementary figure legends and supplementary tables
Figure S5 from Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting
Authors: Cheung Phyllis F. , Neff Florian , Neander Christian , Bazarna Anna , Savvatakis Konstantinos , Liffers Sven-Thorsten , Althoff Kristina , Lee Chang-Lung , Moding Everett J. , Kirsch David G , Saur Dieter , Bazhin Alexandr V. , Trajkovic-Arsic Marija , Heikenwalder Mathias F. , Siveke Jens T.
Published: April 2023

Nanostring PanCancer Immune profiling analysis and validation.
Supplementary Data 4 from Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
Authors: Kimmel Gregory J. , Dane Mark , Heiser Laura M. , Altrock Philipp M. , Andor Noemi
Published: April 2023

Simulation shown in Fig. 4D
Supplementary Data 2 from Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
Authors: Kimmel Gregory J. , Dane Mark , Heiser Laura M. , Altrock Philipp M. , Andor Noemi
Published: April 2023

Simulation parameters
Supplementary Data 1 from Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
Authors: Kimmel Gregory J. , Dane Mark , Heiser Laura M. , Altrock Philipp M. , Andor Noemi
Published: April 2023

Simulated 1D growth patterns
Figure S1 from Fibroblast-Derived IL33 Facilitates Breast Cancer Metastasis by Modifying the Immune Microenvironment and Driving Type 2 Immunity
Authors: Shani Ophir , Vorobyov Tatiana , Monteran Lea , Lavie Dor , Cohen Noam , Raz Yael , Tsarfaty Galia , Avivi Camila , Barshack Iris , Erez Neta
Published: April 2023

Figure S1 complements Figure 1 in showing the specific upregulation of IL-33 in metastases-associated fibroblasts
Figure S1 from Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines
Authors: Valiente Manuel , Van Swearingen Amanda E.D. , Anders Carey K. , Bairoch Amos , Boire Adrienne , Bos Paula D. , Cittelly Diana M. , Erez Neta , Ferraro Gino B. , Fukumura Dai , Gril Brunilde , Herlyn Meenhard , Holmen Sheri L. , Jain Rakesh K. , Joyce Johanna A. , Lorger Mihaela , Massague Joan , Neman Josh , Sibson Nicola R. , Steeg Patricia S. , Thorsen Frits , Young Leonie S. , Varešlija Damir , Vultur Adina , Weis-Garcia Frances , Winkler Frank
Published: April 2023

This figures describes the use of the BrMPanel for brain metastasis research
Table S3, Table S4 from YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
Authors: Shim Jenny , Lee Jasmine Y. , Jonus Hunter C. , Arnold Amanda , Schnepp Robert W. , Janssen Kaitlyn M. , Maximov Victor , Goldsmith Kelly C.
Published: April 2023

RNA sequencing data
Table S1 from Dietary Fructose Promotes Prostate Cancer Growth
Authors: Carreño Daniela V. , Corro Néstor B. , Cerda-Infante Javier F. , Echeverría Carolina E. , Asencio-Barría Catalina A. , Torres-Estay Verónica A. , Mayorga-Weber Gonzalo A. , Rojas Pablo A. , Véliz Loreto P. , Cisternas Pedro A. , Montecinos Viviana P. , San Francisco Ignacio F. , Varas-Godoy Manuel A. , Sotomayor Paula C. , Castro Maite A. , Nualart Francisco J. , Inestrosa Nibaldo C. , Godoy Alejandro S.
Published: April 2023

Biological/clinical parameters (patient age, PSA levels, Gleason score) and glucose and fructose levels in benign and PCa patients.
Figure S2 from Dietary Fructose Promotes Prostate Cancer Growth
Authors: Carreño Daniela V. , Corro Néstor B. , Cerda-Infante Javier F. , Echeverría Carolina E. , Asencio-Barría Catalina A. , Torres-Estay Verónica A. , Mayorga-Weber Gonzalo A. , Rojas Pablo A. , Véliz Loreto P. , Cisternas Pedro A. , Montecinos Viviana P. , San Francisco Ignacio F. , Varas-Godoy Manuel A. , Sotomayor Paula C. , Castro Maite A. , Nualart Francisco J. , Inestrosa Nibaldo C. , Godoy Alejandro S.
Published: April 2023

Glut(s) expression PC-3 cell line-derived xenograft model.