bluuebunny/crossref_metadata_2025 huggingface dataset:
Pages of the history of Vinnytsia Psychoneurological Hospital in book memorabilia
Authors: Mazur O. P.
Published: October 2022

Annotation. The article presents publications on the history of medical psychology and psychiatry with proprietary stamps "Library of Vinnytsia District Hospital", which are stored in the fund of National Pirogov Memorial Medical University, Vinnytsya Scientific Library.
PROFESSIONAL DEVELOPMENT OF PRIMARY SCHOOL TEACHERS IN THE SYSTEM OF METHODICAL WORK OF INSTITUTIONS OF GENERAL SECONDARY EDUCATION
Authors: Shabala Y. A.
Published: October 2022

The article theoretically substantiates the foundations of the professional development of primary school teachers in the system of methodical work of institutions of general secondary education, in particular, the definition of the concept «professional development of primary school teachers in the system of methodical work of institutions of general secondary education» is specified, which we understand as a managed dynamic process, which is inherently aimed at achieving a high level of professional development and develops according to scientific principles and approaches in specific pedagogical conditions, with the use of developed and adapted learning models in accordance with the requirements of the digital society, the concept of the New Ukrainian School, updating the system of methodical work and crisis conditions. Recommendations are given for the purpose of positive dynamics of professional development of primary school teachers in the methodical work system of general secondary education institutions.
MAY THE HONEYCOMB ARCHITECTURAL DEVIATIONS REFLECT THE BEES ENGINEERING PROWESS?
Authors: Pokutsa Alexander , Zaborovskyi Andriy
Published: October 2022

This study affords the experimental evidences elucidate the putative mechanism of the bee comb establishing. Furthermore, the first time discerned skewed triangular prism in the bottom of the cells ab initio built up by Apis mellifera carpatica indicates that the traditional rhombic dodecahedra is not mandatory element of the comb architecture. The revealed oddity is inherent to about one third of the whole number of the cells constitute the analyzed patterns. The building abnormality presumably developed from the primeval manner of cells construction and may be triggered with the volatile natural factors e.g. geographic location and climatic zone, variety of floral shapes, duration of active season as well as bee race. Disclosed constructional diversity mirror the reaction of the colonies on the highlighted disturbances and might be stipulated by the bees’ ability to engineering prowess.
مدخل إلى الفقه المقارن
Authors: هاروش أيمن محمد
Published: October 2022

مر الفقه الإسلامي بأطوار تاريخية عدة تطور فيه من حيث الشكل والمضمون، فبدأ بالاجتهاد زمن الصحابة والتابعين، ثم انتقل لظهور المدارس الفقهية والمذاهب، ثم صار إلى التقليد المحض، ثم ظهر الفقه المقارن في شكله البدائي، ثم تطور في عصرنا حتى صار من أبرز ملامح الدور الفقهي المعاصر ظهور الدراسة الفقهية المقارنة. اعتمد الفقه المقارن المعاصر على دراسة المسائل الخلافية بين المذاهب مع بيان أدلة كل مذهب، والقواعد الأصولية التي أقام عليها مذهبه، ثم مناقشة كل مذهب في أدلته، وبيان قوتها وضعفها، ووجه الاستدلال وانسجامه مع قواعد الأصول، ثم الترجيح وفق قواعد البحث العلمية. لقد كان لظهور الفقه المقارن أثر كبير في إثراء المكتبة الفقهية، وتوسعة العقلية الفقهية عند الباحثين، وتقريب كبير بين المذاهب، وإزالة حدة التعصب المذهبي، وإنصاف العلماء في خلافاتهم، وصقل الملكية الفقهية عند الباحثين، ونقل القواعد الأصولية من التنظير إلى التطبيق العملي. وفي هذا البحث نقدم مدخلًا للفقه المقارن، نبين فيه مفهوم الفقه المقارن، وتاريخ نشأته، وفوائده، ومنهج البحث فيه، والملاحظات عليه، ونقدم توصيات للباحثين في الفقه خصوصًا وفي الخلاف عمومًا.
Translation of Collaborative Dementia Care Management into Different Healthcare Settings: Study Protocol for a Multicenter Implementation Trial (DCM:IMPact)
Authors: Platen Moritz , Hoffmann Wolfgang , Rädke Anika , Scharf Annelie , Mohr Wiebke , Mühlichen Franka , Michalowsky Bernhard
Published: October 2022

Background:

Collaborative care models for people living with dementia (PwD) have been developed and evaluated, demonstrating safety, efficacy, and cost-effectiveness. However, these studies are based on heterogeneous study populations and primary care settings, limiting the generalizability of the results. Therefore, this study aims to implement and evaluate collaborative care across various healthcare settings and patient populations.

Objective:

To describe the study design of this multicenter implementation trial.

Methods:

This single-arm, multicenter, longitudinal implementation study will be conducted in five different healthcare settings, including 1) physicians’ networks, 2) dementia networks, 3) counselling centers, 4) hospitals, and 5) ambulatory care services. Eligibility criteria are: having a formal dementia diagnosis or having been screened positive for dementia and living community-dwelling. The staff of each healthcare setting identifies patients, informs them about the study, and invites them to participate. Participants will receive a baseline assessment followed by collaborative individualized dementia care management, comprising proven safe, effective, and cost-effective modules. Over six months, specially-qualified nurses will assess patients’ unmet needs, transfer them to individualized care plans, and address them, cooperating with various healthcare providers. A follow-up assessment is conducted six months after baseline. Approximately 60–100 PwD per setting per year are expected to participate. Differences across settings will be assessed regarding acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness.

Results:

We expect that acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness will vary by patients’ sociodemographic and clinical characteristics and unmet needs in each setting.

Conclusion:

The results will provide evidence highlighting differences in the implementation of collaborative care in various healthcare settings and demonstrating the settings with the highest need, best conditions for a successful implementation, and highest (cost-)effectiveness, as well as the population group that benefits most from collaborative care.

Trial registration:

German Clinical Trials Register: DRKS00025074. Registered 16 April 2021-retrospectively registered.
Skin microcirculation reactivity to local thermal hyperaemia in patients with COVID-19 — A pilot observational study
Authors: Glazkov A.A. , Ulbashev D.S. , Borshchev G.G. , Pulin A.A. , Glazkova P.A. , Kulikov D.A.
Published: October 2022

BACKGROUND: Endothelial dysfunction and microvascular disturbances are suggested to play a key role in higher morbidity and worse prognosis in patients with COVID-19 and cardiometabolic diseases. OBJECTIVE: Study was aimed to establish relationships between the skin microcirculation parameters and various clinical and laboratory indicators. METHODS: The study included 18 patients with moderate disease according to WHO criteria. Skin microcirculation measurements were performed by laser Doppler flowmetry using a heating test on the hairy skin of the right forearm. RESULTS: Baseline perfusion only correlated with C-reactive protein (Rs = 0.5, p = 0.034). Microcirculation indices characterising the development of hyperaemia during the first minute of heating (LTH1 and AUC60) showed significant correlations (Rs from 0.48 to 0.67, p < 0.05) with indices of general blood analysis and blood coagulation (fibrinogen, D-dimer, haemoglobin, erythrocyte count and haematocrit). Indexes characterising the dynamics of hyperaemia development over longer time intervals showed correlation with the glomerular filtration rate (Rs = 0.6, p = 0.009). CONCLUSION: Known COVID-19 risk factors (haemorheological parameters, age) are correlated with the microvascular reactivity to heating in patients with COVID 19. We suggest that, prospectively, the method of laser Doppler flowmetry could be used for non-invasive instrumental assessment of microcirculatory disorders in patients with COVID-19.
Circ_HECW2 regulates ox-LDL-induced dysfunction of cardiovascular endothelial cells by miR-942-5p/TLR4 axis
Authors: Wei Wenbo , Tang Min , Wang Qi , Li Xiaoming
Published: October 2022

BACKGROUND: Coronary artery disease (CAD) is a common coronary artery disease. The functional mechanism of circular RNA (circRNA) HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 (circ_HECW2, hsa_circ_0057583) in ox-LDL-treated human cardiac microvascular endothelial cells (hCMECs) is still unclear. METHODS: Expression levels of circ_HECW2, microRNA (miR)-942-5p, and toll-like receptor 4 (TLR4) were analyzed by quantitative real-time PCR (qRT-PCR) and western blot assays. Cell proliferation and apoptosis were analyzed by 5-ethynyl-2’-deoxyuridine (EdU) assay, cell counting kit-8 (CCK8) assay, and flow cytometry, respectively. Tube formation assay was performed to analyze the angiogenesis of cells. Luciferase reporter and RNA pull-down assays were performed to analyze the target relationship among circ_HECW2, miR-942-5p and TLR4. RESULTS: Circ_HECW2 and TLR4 expression levels were up-regulated and miR-942-5p expression was decreased in the serum of CAD patients and oxidized low-density lipoprotein (ox-LDL)-induced hCMECs. Knockdown of circ_HECW2 enhanced cell proliferation and inhibited cell apoptosis in ox-LDL-treated hCMECs. MiR-942-5p was the target of circ_HECW2 and directly targeted TLR4. Moreover, the effect of circ_HECW2 knockdown could be weakened by anti-miR-942-5p, and TLR4 could restore the function of miR-942-5p on cell damage of ox-LDL-induced hCMECs. CONCLUSION: Circ_HECW2 could regulate ox-LDL-induced cardiovascular endothelial cell dysfunction through targeting miR-942-5p/TLR4 axis.
Cancer and Vascular Comorbidity Effects on Dementia Risk and Neuropathology in the Oldest-Old
Authors: Lachner Christian , Day Gregory S. , Camsari Gamze Balci , Kouri Naomi , Ertekin-Taner Nilüfer , Boeve Bradley F. , Labuzan Sydney A. , Lucas John A. , Thompson E. Aubrey , Siddiqui Habeeba , Crook Julia E. , Cabrera-Rodriguez Janisse N. , Josephs Keith A. , Petersen Ronald C. , Dickson Dennis W. , Reichard R. Ross , Mielke Michelle M. , Knopman David S. , Graff-Radford Neill R. , Murray Melissa E.
Published: October 2022

Background: Dementia, vascular disease, and cancer increase with age, enabling complex comorbid interactions. Understanding vascular and cancer contributions to dementia risk and neuropathology in oldest-old may improve risk modification and outcomes. Objective: Investigate the contributions of vascular factors and cancer to dementia and neuropathology. Methods: Longitudinal clinicopathologic study of prospectively followed Mayo Clinic participants dying≥95 years-old who underwent autopsy. Participants were stratified by dementia status and compared according to demographics, vascular risk factors, cancer, and neuropathology. Results: Participants (n = 161; 83% female; 99% non-Hispanic whites)≥95 years (95–106 years-old) with/without dementia did not differ based on demographics. APOE ɛ2 frequency was higher in no dementia (20/72 [28%]) versus dementia (11/88 [12%]; p = 0.03), but APOE ɛ4 frequency did not differ. Coronary artery disease was more frequent in no dementia (31/72 [43%]) versus dementia (23/89 [26%]; p = 0.03) associated with 56% lower dementia odds (odds ratio [OR] = 0.44 [confidence interval (CI) = 0.19–0.98]; p = 0.04) and fewer neuritic/diffuse plaques. Diabetes had an 8-fold increase in dementia odds (OR = 8.42 [CI = 1.39–163]; p = 0.02). Diabetes associated with higher cerebrovascular disease (Dickson score; p = 0.05). Cancer associated with 63% lower dementia odds (OR = 0.37 [CI = 0.17–0.78]; p < 0.01) and lower Braak stage (p = 0.01). Conclusion: Cancer exposure in the oldest-old was associated with lower odds of dementia and tangle pathology, whereas history of coronary artery disease was associated with lower odds of dementia and amyloid-β plaque pathology. History of diabetes mellitus was associated with increased odds of dementia and cerebrovascular disease pathology. Cancer-related mechanisms and vascular risk factor reduction strategies may alter dementia risk and neuropathology in oldest-old.
Associations of Pulmonary Function with MRI Brain Volumes: A Coordinated Multi-Study Analysis
Authors: Frenzel Stefan , Bis Joshua C. , Gudmundsson Elias F. , O’Donnell Adrienne , Simino Jeannette , Yaqub Amber , Bartz Traci M. , Brusselle Guy G. O. , Bülow Robin , DeCarli Charles S. , Ewert Ralf , Gharib Sina A. , Ghosh Saptaparni , Gireud-Goss Monica , Gottesman Rebecca F. , Ikram M. Arfan , Knopman David S. , Launer Lenore J. , London Stephanie J. , Longstreth W.T. , Lopez Oscar L. , Melo van Lent Debora , O’Connor George , Satizabal Claudia L. , Shrestha Srishti , Sigurdsson Sigurdur , Stubbe Beate , Talluri Rajesh , Vasan Ramachandran S. , Vernooij Meike W. , Völzke Henry , Wiggins Kerri L. , Yu Bing , Beiser Alexa S. , Gudnason Vilmundur , Mosley Thomas , Psaty Bruce M. , Wolters Frank J. , Grabe Hans J. , Seshadri Sudha
Published: October 2022

Background: Previous studies suggest poor pulmonary function is associated with increased burden of cerebral white matter hyperintensities and brain atrophy among elderly individuals, but the results are inconsistent. Objective: To study the cross-sectional associations of pulmonary function with structural brain variables. Methods: Data from six large community-based samples (N = 11,091) were analyzed. Spirometric measurements were standardized with respect to age, sex, height, and ethnicity using reference equations of the Global Lung Function Initiative. Associations of forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and their ratio FEV1/FVC with brain volume, gray matter volume, hippocampal volume, and volume of white matter hyperintensities were investigated using multivariable linear regressions for each study separately and then combined using random-effect meta-analyses. Results: FEV1 and FVC were positively associated with brain volume, gray matter volume, and hippocampal volume, and negatively associated with white matter hyperintensities volume after multiple testing correction, with little heterogeneity present between the studies. For instance, an increase of FVC by one unit was associated with 3.5 ml higher brain volume (95% CI: [2.2, 4.9]). In contrast, results for FEV1/FVC were more heterogeneous across studies, with significant positive associations with brain volume, gray matter volume, and hippocampal volume, but not white matter hyperintensities volume. Associations of brain variables with both FEV1 and FVC were consistently stronger than with FEV1/FVC, specifically with brain volume and white matter hyperintensities volume. Conclusion: In cross-sectional analyses, worse pulmonary function is associated with smaller brain volumes and higher white matter hyperintensities burden.
The Impact of Foreign Direct Investment on Environmental Quality in ASEAN Countries
Authors: Sitthivanh Phoumyxay , Srithilat Khaysy
Published: October 2022

Purpose: The purpose of this paper is to examine the impact of foreign direct investment (FDI) on environmental quality in ASEAN countries, the most FDI-attractive region. Design/methodology/approach: This study using the panel time series Pedroni cointegration approach with Fully Modified Ordinary Least Square and Dynamic Ordinary Least Square. This research analyses data from nine ASEAN countries from 2005 to 2018. Findings: The paper finds that there is cointegration between the variables studied in the study. In addition, long-term economic growth and FDI have a significant impact on ASEAN’s environmental quality. Panel granger causality results also reveal a bidirectional causality between FDI and trade openness, growth in the GDP, fuel consumption, and the population in ASEAN. Foreign direct investment is important not only for promoting economic growth and development in ASEAN countries, but it also helps to improve environmental quality in the region. Research limitations/implications: Due to data availability constraints, the study cannot include Myanmar data.
India’s Solar Energy Transition: a perspective of an accountability crisis
Authors: Banerjee Soham
Published: October 2022

India’s announcement at the Glasgow Climate Conclave in 2021, regarding the nation’s short- and long-term climate actions portrayed an ambition of becoming a green leader in the years to come. The article discusses how accountability has broad horizons which in turn is linked with legitimacy, often neglected in research and when incorporated, in relevance to India’s solar energy transition will revolve around accountability crisis. An accountability–legitimacy framework is created in which the Indian solar energy paradigm is tested where the major findings are solar uptake discrepancies, pertinent to four typologies of legitimacy—technocratic, bureaucratic, financial, and discursive.
Implications of Carbon Border Adjustment Mechanism: a case of India’s exports to European Union
Authors: Sharma Vatsala , Gupta Khushi
Published: October 2022

Globalization has integrated national and regional economies into a single vast global economy opening up several prospects of growth and dynamic development, largely because of increased opportunities for international trade (Surugiu, et al. 2015). Now governments around the world have liberalized their trade and financial markets, resulting in intensified flow of goods, capital and services within countries, providing economic benefits. However, this has also resulted in degrading of Earth’s environment. The situation has become so grim, that the occurrence of climate-induced natural hazards is now a frequent event. Carbon neutrality (or net zero emission) has been proposed as a solution to anthropogenic climate change and more countries are committing to reach carbon neutrality by the middle of this century. An example of these is the European Union (EU), which wants to become the first region in the world to commit to net zero emissions by 2050. Its carbon neutrality strategy document, ‘European Union Green Deal (EUGD)’, along with other provisions includes taxing imported goods based on carbon embodied in production, known as Carbon Border Adjustment Mechanism (CBAM). The CBAM suggests taxing the difference between carbon embodied in domestically produced and imported goods. The adjustment mechanism is based on the idea that a price on carbon consumption will encourage countries to adopt cleaner technologies in production process, along with avoiding carbon leakages to other countries with relaxed environmental standards. This paper tries to understand the concept, rationale, proposed working and discussions around CBAM. It also tries to examine the possible effect of CBAM on carbon intensive and trade exposed (CITE) sectors in India. The paper concludes that iron and steel will be the sectors most affected from CBAM in India and suggests that India and EU must harness increased international cooperation (through Free Trade Agreement) to fulfill twin purposes of economic development and environmental conservation.
Experiences in the return-to-work process of workers having suffered occupational injuries in small and medium size enterprises
Authors: Audet Jessika , Lecours Alexandra , Nastasia Iuliana
Published: October 2022

BACKGROUND: Small and medium-sized enterprises (SMEs) represent 95 % of businesses and are economically essential. When occupational injuries occur, scientific literature suggests that the return-to-work (RTW) success rate is proportional to the size of enterprises and the way RTW is managed may put workers in SMEs at risk. As most studies on RTW organizational practices have been conducted with large enterprises, little is known about how RTW is managed in SMEs. OBJECTIVE: The aim of this study was to explore SME’s organizational practices in the RTW process of workers having suffered an occupational injury. METHODS: Semi-structured phone interviews were conducted with 15 participants from 3 different stakeholder categories (i.e., SME representatives, workers, and healthcare professionals) in order to explore their experiences regarding RTW in SMEs. Data were analyzed using a phenomenological analysis strategy. RESULTS: SMEs’ organisational practices evoked by participants gather in three themes: 1) Reducing the risks of occupational injuries (i.e., ensuring injury prevention), 2) Managing occupational injuries (i.e., dealing with the initial occupational injury, handling administrative aspects of work disability, and being actively involved in the RTW process), and 3) Preventing consequences of occupational injuries (i.e., adapting operations following injuries). CONCLUSION: Organizational practices for RTW are used diversely in SMEs. Proposed lines of action adapted to the realities and needs of SMEs may be beneficial to hundreds of thousands of workers, enterprises and professionals involved in the RTW process.
Dough kneading exposure at the kitchen workstation: Influence on handgrip strength and implications for therapy in hand rehabilitation
Authors: Khan Lubna , Shetty Mamta , Kherada Shifa , Kava Reema , Kazi Mubina , Walankar Prachita , Mullerpatan Rajani
Published: October 2022

BACKGROUND: Dough kneading is a commonly performed activity in the kitchen, which influences hand grip strength. OBJECTIVES: To study the influence of dough kneading exposure on hand grip strength and to evaluate the effect of dough kneading intervention on hand grip strength with the purpose of recommending dough kneading as a therapeutic exercise for improving hand grip strength. METHODS: One hundred and fifty healthy females with varying levels of exposure to dough kneading, stratified as occupational dough kneaders, habitual dough kneaders and non-kneaders, were studied. Hand grip strength of all participants was measured with a standard protocol using the Jamar dynamometer. Hand grip strength of occupational, habitual and non-kneaders was compared. Non-kneaders followed a 6-week intervention of dough kneading and grip strength was recorded post-intervention. RESULT: Comparison of hand grip strength between the three groups revealed significant difference (p value < 0.001). Linear contrast analysis, revealed the least hand grip strength in non-kneaders compared to habitual and occupational dough kneaders, with occupational dough kneaders presenting maximum hand grip strength (p value < 0.001). Significant improvement was demonstrated in hand grip strength post-intervention in non-kneaders (p value < 0.001). CONCLUSION: Findings suggest that exposure to dough kneading has a positive influence on hand grip strength. Hand grip strength of non-kneaders was lowest compared to habitual and occupational kneaders. Kneading intervention improved hand grip strength and hence can be used therapeutically as a safe, low cost exercise in hand rehabilitation.
Structure of the Blood Brain Barrier and the Role of Transporters in the movement of substrates across the barriers
Authors: Singh Ankul , Vellapandian Chitra
Published: October 2022

The blood brain barrier present in brain capillaries constitutes an essential barrier mechanism for normal functioning and development of the brain of structural integrity besides neuronal function. The structure and function of the BBB are summarised besides the physical barrier formed by the endothelial tight junctions, and the transport barrier resulting from membrane transporters and vesicular mechanisms. The presence of tight junctions between adjacent endothelial cells restricts the permeability and movement of molecules between extracellular fluid and plasma. It is divided into luminal and abluminal where each solute must cross both membranes. The roles of the neurovascular unit are outlined, especially the astrocyte endfeet, pericytes, and microglia. Five different systems of facilitative transport are found in the luminal membrane and are specific for a few substrates. Nonetheless, two major facilitative carriers (System L and y+) are located in both membranes asymmetrically. In contrast, several Na+ dependent transport systems transport amino acids against its concentration gradient present in the abluminal membrane, where the sodium pump Na+/K+-ATPase is highly expressed. The trojan horse mechanism is also favoured in drug delivery by employing molecular tools to bind the drug and its formulations. In the current work, we have revised the prevailing knowledge on the cellular structure of the BBB and the transport systems present exclusively for each substrate, and the need to find transporters with modifications that facilitate the transport of various drugs. Nevertheless, the blending of the classical pharmacology with nanotechnology needs to be focussed on promising results to rule out the BBB passage for the new generation of neuroactive drugs.
High diversity and transmission dynamics of HIV-1 non-C subtypes in Bangladesh
Authors: Sarker Md. Safiullah
Published: October 2022

BACKGROUND. Genetic diversity and molecular epidemiology of HIV are directly relevant to HIV transmission. We report here the genetic diversity and transmission dynamics of non-C subtypes of HIV-1 strains detected in Bangladeshi key populations. 

RESULTS. Sequence analysis of _gag_ gene revealed four subtypes A1, B, D, G and nine CRFs (01_AE, 02_AG, 09_cpx, 10_CD, 15_AE/B, 13_cpx, 14_BG, 22_01_A1 and 25_AGU). Most of these non-C strains were detected in returnee migrant workers from different parts of the world. Phylogenetic analysis showed that the Bangladeshi HIV-1 strains detected in migrant workers and their wives and local sex workers shared common ancestries.

CONCLUSIONS. Identification of the multiple subtypes indicates high diversity of non-C HIV-1 variants circulating in Bangladesh which might have been imported by migrant workers from multiple geographical areas.
Biology Undergraduate Students’ Views of Assessment:
Authors: Pereira Diana , Santos Patrícia , Aguiar Cristina , Flores Maria Assunção
Published: October 2022

This paper draws on data from research focusing on assessment methods, its purposes and effects, effectiveness and fairness, as well as student participation and feedback. In total, 124 Biology undergraduate students participated in the study. Data were collected through questionnaires and focus groups. Findings reveal written test as the most used method and that students associate assessment mainly with a summative purpose. Although students report they negotiate some assessment-related aspects with their teachers, in general they do not participate in self and peer assessment. Feedback is clearly recognized an important feature in the assessment process. Implications of the present findings are discussed.
THE RELATIONSHIP BETWEEN FEAR OF COVID-19 AND ADHERENCE FOR PEOPLE WITH END STAGE RENAL DISEASES WITH HEMODIALYSIS
Authors: Astuti Nining Puji , Baidhowy Arief Shofyan , Nugroho Erlangga Galih Zulva
Published: October 2022

Patients with End-Stage Renal Disease (ESRD) are highly vulnerable with the multiple comorbidities that make them susceptible to adverse outcomes with COVID-19. Over 2 million people worldwide receive maintenance hemodialysis (HD) at outpatient centers. In Indonesia, people have to come to dialysis centre at hospital for maintenance dialysis although in pandemic. Governments have been trying to fight the outbreak, by enacting various restrictions to maintain social distancing and effectively preventing the spread of infection among HD centre, healthcare personnel, and patients is essential to ensure the continued delivery of dialysis to ESRD patients but this condition affect in mental health people with hemodialysis such as fear of covid-19. The present study aimed to understand the relationship between fear of covid-19 and adherence people with hemodialysis to maintaining hemodialysis at hospital. The study group of the research consisted of 60 patients with hemodialysis were selected by the purposive sampling method. The research method is the correlational survey model. Data was obtained using the Demographic Information Form, fear of covid-19 scale and The End Stage Renal Disease Adherence Questionnaire (ESRD-AQ). Group comparison analysis revealed that women experienced higher levels of fear of the coronavirus. While those with postgraduate education reported significantly lower levels of fear of the coronavirus than those with other education levels. Fear of the coronavirus did not differ according to the age range, income level, and marital status of the participants. According to the results of the correlation analysis, a positive correlation between the fear of coronavirus and adherence people with hemodialysis to take medication at hospital was found.
Rational control of the temperature of vortex energy separator under destabilizing influence
Authors: Kulik Anatoliy , Dergachov Kostiantyn , Pasichnik Sergiy , Sokol Dmytro
Published: October 2022

The object of study in this article is the formation process of a rational control of the temperature of a vortex energy separator under destabilizing influences. The subject matter of the article is the process of forming a dichotomous tree by two-digit predicates from diagnostic models a vortex energy-separator device as a rational control object when destabilizing influences appear, and its further recovery. The goal is to develop an analytical approach to the formation of digital algorithms for the rational control of cold and hot air flow temperatures of a vortex energy separator. The tasks are to study the features of the process in the vortex energy-separator device; to describe a rational control system of the vortex energy-separator device; to analyze the experimental characteristics of the vortex energy-separator device; to form linear mathematical models of the nominal mode of the vortex energy-separator device; to develop linear diagnostic models that describe the inoperable states of the vortex energy separator as a rational control object; to form logical signs of diagnosing using diagnostic models, to develop recovering algorithms for the vortex energy separator. The methods used are transfer functions, discrete state space, forming production rules, two-digit predicate equations, dichotomous trees, diagnosing and recovering the operability of dynamic objects. The following results were obtained: the vortex energy-separation process features analysis, the rational control system structure and function description, the experimental characteristics analysis, the development of mathematical models, diagnostic and recovering tool development for the emergency operation process of a vortex energy separator as a rational control object for a given destabilizing influence set. Conclusions. Scientific novelty is the development of an analytical approach to the development of rational control of the vortex separation process of the air flow under the significant influence of various kinds of destabilizing influences.
Carcinoma epidermóide de amígdala pós-transplante cardíaco - relato de caso
Authors: Giffhorn Hélcio , Pifer K. E. , Almeida R. S. , Ferreira M. J. A. , Ribeiro E. J. , Rossi P. R. F. , Pereira M. A. A. , Bueno R. R. L. , Andrade P. M. P. , Simões J. C. , Loures D. R. R.
Published: October 2022

Paciente de 52 anos submetida a transplante cardíaco ortotópico em maio de 1991, tendo apresentado como complicação tardia o surgimento de carcinoma epidermóide de amígdala. O diagnóstico inicial foi de neoplasia metastática de sítio primário desconhecido porque o tumor primário somente manifestou-se após 6 meses do surgimento da metástase à distância. A incidência de neoplasia no primeiro ano pós-transplante cardíaco é pouco freqüente, assim como o carcinoma epidermóide de amígdala na populações normal. Não encontramos relato de caso na literatura entre pacientes submetidos a transplante cardíaco e apresentando carcinoma epidermóide de amígdala.
Abdome agudo obstrutivo por metástase de melanoma maligno: relato de caso
Authors: Ros Carlos Teodósio Da , Silva Fabiano Ligório da , Guedes Ernesto de Paula , Hartmann Antônio A.
Published: October 2022

Apresentamos o caso de um paciente com obstrução intestinal aguda causada por metástase de melanoma maligno intestinal, o qual tinha sido submetido, dois anos antes, à ressecção de um melanoma maligno na região dorsal. Trata-se de uma neoplasia infreqüente cujo sítio metastático, do caso em questão, é ainda mais raro.
Decisão médica ética em casos de pacientes terminais
Authors: Koseki Nancy Mineko , Bruera Eduardo
Published: October 2022

Os profissionais da saúde que cuidam de doentes terminais muitas vezes enfrentam a angústia, o dilema de decidir qual a melhor conduta para estes pacientes, quando iniciar, manter ou suspender um determinado tratamento. Muitas decisões interferem direta ou indiretamente no processo de morte, podendo antecipá-la, apesar de não ser esta a intenção primária. Neste artigo, fazemos uma breve revisão sobre os princípios éticos básicos que direcionam o processo de “decisão” que pode resultar em dois amplos caminhos de ação em relação ao tratamento. Apresentamos alguns casos como ilustração para discutir estas considerações éticas e teológicas.
Competitiveness of the Commodity Indonesian Coffee Beans the International Market
Authors: Adnan Adnan , Teniro Alwin , Zainudin Zainudin -
Published: October 2022

The Geographical Indication Program (IG) with the application of fairtrade standardization has been launched by the Indonesian government in 2001, to increase the competitiveness of local products in the international market. This study seeks to identify the strength of competitiveness and the position of Indonesian bean coffee commodities in the international market and each of the national markets of the importing country. Panel data used during the period 2010-2021 covered 11 exporter countries and 6 importer countries, analyzed with the RCA index. The results showed that Coffee not Roasted or Decaffeinated has strong competitiveness in the international market and some national markets of importing countries, and competitiveness is weak for Coffee Roasted, not Decaffeinated. The competitiveness position of the two coffee bean commodities is in the 6th position. The occurrence of a positive correlation between the contribution of exports and the competitiveness of coffee beans indicates the positive impact of the IG program and suggests that the position of competitiveness be improved through the provision of adequate and affordable organic production facilities, farmer counseling, and partnership and promotion cooperation.
Peran Cyberloafing Terhadap Produktivitas Karyawan Dengan Kesehatan Mental Sebagai Pemediasi
Authors: Triyanti Triyanti , Amelia Windharti , Maharani Anita , Pandu Thenry Linda Sharron
Published: October 2022

This study aims to determine the effect of Cyberloafing and Productivity with Mental Health as a mediator. This research uses a quantitative approach method and the sample is taken using a random probability sampling technique with the population being employees of companies in Indonesia that carry out cyberloafing. Data collection was done online using google form and resulted in 193 responses that could be used. The results showed that all hypotheses were not supported, which means that cyberloafing had no effect on mental health and productivity. Further testing with Multi-Group Analysis (MGA) found that the characteristics of the respondents showed different results. In male respondents, cyberloafing had a positive effect on productivity. The respondents from service industry employee group also showed similar results, cyberloafing had a positive effect on productivity. Meanwhile, in respondents with married status showed that cyberloafing had a negative effect on mental health and productivity. These interesting findings from the test results on different characteristics of respondents can enrich studies on cyberloafing, mental health and employee productivity. The results obtained from this study are expected to provide benefits for company management in regulating internet use policies during working hours to ensure employee productivity is maintained.
Magnetic Resonance Imaging (MRI) Features in Diagnosing Tumefactive Demyelinating Lesion.
Authors: Foo See Yun , Rahim Nurul Hafidzah , Mohd Mustapha Aida Widure Mustapha , Mohd Zaini Noraini Rose
Published: October 2022

Background: A demyelinating lesion can present as a space occupying lesion in Magnetic Resonance Imaging (MRI) brain. Lesions that have diameter greater than 2 cm is referred as tumefactive demyelinating lesion. These lesions can mimic a brain tumor, namely glioma or primary central nervous system lymphoma.
Case presentation: We present two female patients over 30 years old who presented with limb weakness. Their MRI demonstrated typical appearance of a solitary, incomplete rim enhancing lesion that involved the subcortical white matter with minimal mass effect. Also, the rim of enhancement opened to the grey matter. Due to their typical appearance, biopsy was not performed. The lesions in both patients reduced in size upon follow up after treatment commencement and currently recovering.
Conclusion: In this case report, we focus on discussing the MRI features of tumefactive demyelinating lesion and its main differentials, which are central nervous system lymphoma (CNSL) and glioma.
INFLUENCE OF BUSH LOAD WITH SHOOTS OF KRASNOSTOP AZOS VARIETY ON GRAPES AND WINE QUALITY
Authors:   Anapa Zonal Experimental Station of Viticulture and Winemaking – branch of the Federal State Budgetary Scientific Institution ", Kurdenkova E.K. ,   North Caucasus Federal Scientific Center of Horticulture, Viticulture, Winemaking", Akhmedova J.A. ,   Anapa Zonal Experimental Station of Viticulture and Winemaking – branch of the Federal State Budgetary Scientific Institution "North Caucasus Federal Scientific Center of Horticulture, Viticulture, Winemaking"
Published: October 2022

The results of studies on the optimal load of bushes with shoots on fruitfulness, productivity of a grapevine plant and quality indicators are presented. The purpose of the work is to identi-fy the optimal load that allows you to manage the productivity, quality of grapes and wine of Krasnostop AZOS variety. The work was car-ried out in the industrial vineyards of the Temryuk district of the Krasnodar Territory, st. Starotitoravskaya agricultural firm LLC "Fana-goria-South". The objects of research were grapes and wine material from the Krasnostop AZOS variety. The area of the experimental plot is 1 ha. Planting scheme: 3×2 m. The shape of the bushes is a spiral high-stem cordon. The grape culture is own-rooted. Agrotechnical studies were carried out according to generally accepted methods in viticulture. Wine materials were prepared by the method of microwine-making according to National Standsrt 52523-2006. Three load rates were tested: 35, 40, 46 pcs/bush. In terms of fruitfulness, variants with a load of 40 and 35 shoots per bush were iden-tified as the best (the percentage of fruitful shoots was 87 and 88). According to the coef-ficient of fruiting (K1) and fruitfulness (K2), a variant with a load of 46 shoots per bush stood out, and had the following indicators ‒ 1.6, respectively 1.9. According to the yield size, the variant with a maximum load of 46 shoots per bush ‒ 16.8 t/ha with a low mass concentra-tion of sugars in the berry juice (22.7 g/dm3) was selected. High sugar values were recorded in the variant with a low load (35 shoots per bush) ‒ 24.4 g/dm3. The concentrations of ti-tratable acids differed slightly in all variants of the experiment. The highest tasting score of 8.3 was obtained in the variant with a load of 35 shoots per bush.
AGROBIOLOGICAL ASSESSMENT AND YIELD OF AUTOCHTHONIC DON GRAPE VARIETIES IN THE COLLECTION IN 2021
Authors:   All-Russian research Ya.I. Potapenko institute for viticulture and winemaking - branch of Federal state budget scientific institution «Federal Rostov agricul-tural research centre», Naumova L.G. , Ganich V.A. ,   All-Russian research Ya.I. Potapenko institute for viticulture and winemaking - branch of Federal state budget scientific institution «Federal Rostov agricul-tural research centre»
Published: October 2022

The results of observations and studies of au-tochthonous Don varieties in 2021 at the Don ampelographic collection named after Ya.I. Potapenko (Novocherkassk, Rostov region). Varieties were studied in grafted, covering cul-ture. The object of research were 22 varieties of grapevine of different directions of use and time of maturation. The most of the studied varieties had a percentage of blossoming buds from 60 to 80%, with the exception of 8 varie-ties having from 81.1 to 90% of blossoming buds, to the lower side – one variety – Sivolistny (32.9% of blossoming buds). The percentage of fruitful shoots varied in a wide range, from 28 to 82%, while the majority of varieties (73% of the studied) had this indicator – below 50%. The largest average bunch weight was in the technical variety Bezymyanny Donskoy (567 g), the table variety – Shi-lokhvosty (531 g), the universal variety – Krestovsky (406 g). The yield of varieties was different, and varied in a wide range, from 1.1 kg/bush (Sivolistny) to 8.7 kg/bush (Bes-sergenevsky 10). The yields of more than 100 c/ha had varieties – Bessergenevsky 10, Bezymyanny Donskoy, Shilokhvosty, Sibirkovy, Durman, Shampanchik 2, Pukhlya-kovsky. According to the harvest conditions, there were 9 varieties with high and medium sugar content of berry juice in each group, 1 variety was with low sugar content, and 2 with very low sugar content. Very high sugar con-tent of berry juice was in one variety – Svetlo-listniy (23.4 g/100 cm3). According to titratable acidity: high acidity was noted in 6 varieties, the most of varieties (12) had medium acidity (from 7 to 9 g/dm3), 3 varieties had low acidity (4–6 g/dm3). According to the results of the research, it can be preliminarily identified as promising in terms of yield and quality of grapes for winemaking among technical and universal varieties – Bezymyanny Donskoy, Bessergenevsky 10, Sibirkovy, Durman, Sham-panchik 2, Pukhlyakovsky.
Black Media Reporting on Theater, Dance, and Jazz Clubs in Canada: From Shuffle along to Rockhead’s Paradise
Authors: Thompson Cheryl , Jabouin Emilie
Published: October 2022

Canada has a history of de facto Jim Crow (1911–1954). It also has a historical Black press that is intimately connected to Black America through transnational conversations, and diasporic migration. This article argues that Canada’s Black newspapers played a pivotal role in promoting Black performance during a time when they were scarcely covered in the dominant media. Drawing on news coverage from the 1920s through 1950s of black dance, musicals, and jazz clubs this article examines three case studies: Shuffle Along (1921–1924), the first all- Black Broadway musical to appear at Toronto’s Royal Alexandra Theater, Alberta-born dancer Len Gibson (1926–2008), who revolutionized modern dance in Canada in the 1940s and 1950s, and the Montreal jazz club Rockhead’s Paradise (1928–1980), a pivotal site

in the city’s Little Burgundy, a Black neighborhood that thrived in the 1930s through 1950s. The authors argue that when Black people were excluded from and/or derogatorily portrayed in the dominant media, Canada’s Black press celebrated collective achievement by authenticating Black performance. By incorporating Canada’s Black Press into conversations about Jim Crow and performance, we gain a deeper understanding of Black creative output and resistance during the period.
Can Assembly Performance and Work Environment be Jointly Optimized? An Example Discreet Event Simulation Study
Authors: Neumann Patrick , Medbo P
Published: October 2022

We demonstrate here how discreet event simulation can be used to integrating ergonomics into design processes. In this case we test the effect of two different ways of organizing work within a conventional production line layout. We pay special attention to the sensitivity of the system to human factors such as work autonomy and reduced work pace. Results indicate the general superiority of a ‘dual-cell’ over a ‘chase-the-rabbit’ organization in accommodating human variability. The study shows how human considerations can be tested in the design process using flow simulation.

 Keywords:  Flow, Simulation, Production System Design,   Psychosocial Conditions, Work Organization 
A Case Study of the Ergonomic Consequences of Engineering Decisions
Authors: Neumann Patrick , Kihlberg S. , Medbo P. , Winkel Jorgen
Published: October 2022

This paper presents a case study of the ergonomic consequences of engineering change.  Within the context of a project to re-design an electronics assembly system a decision was made to automate transportation functions.   A manual batch-cart system was changed to a line-system with automatic conveyors. 
A Study on the Effect of Social Distancing on Offline Consumption Patterns: A Case Study about Convenience Store
Authors:   The Korean Production And Operations Management Society, Park Jihyun , Lee Seungjun , Ryu Seungwan
Published: October 2022

Amid the continuous spread of the COVID-19 pandemic, analyzing how social distancing policies affect customers' consumption patterns is a critical issue in offline retailers' operation management. This study investigates the changes in customers' consumption behavior since COVID-19 imposed restrictions, using sales data of convenience stores in 2019 and 2020. Mainly, we conduct an empirical study on how the social distancing policy affects consumers'purchasing behavior. The regression result reveals that the reinforcement of the social distancing policy positively affects the weekly sales of convenience stores. In addition, the social distancing policy negatively interacts with the region's population density to harm the weekly sales of convenience stores. This study contributes to the literature by analyzing consumption behavior using actual offline consumption data of people within the framework of the Institution Theory. The result of this study can help offline retailers establish inventory management and operation strategies.
Proposal of Logistics Service Evaluation Framework from the Perspective of Service Purchase
Authors:   The Korean Production And Operations Management Society, Pyun Jebum , Choi Donghyun , Kim Seungbeom
Published: October 2022

In this study, we analyze the logistics service process for the improvement of win-win cooperation and competitiveness of the logistics industry ecosystem., and based on this, we propose an evaluation framework that can entrust the final logistics service. In the process of providing logistics services, an LLP may enter into a consignment contract with a partner (supplier) to perform a part of the logistics service. Therefore, this study proposes a method to analyze the various functions provided from the perspective of the process, rather than the industry classification based on the framework act on logistics policies. In addition, from the perspective of service purchase and supply, we propose an evaluation framework that can be referred to in the creation of a business ecosystem and strategic nurturing of the logistics industry. To this end, AHP analysis was performed through expert inverview to derive evaluation priorities in four aspects: the importance of the business, profit of the LLP, profit of the partner(supplier), and resilience.