bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementing I-CBT (Moodgym) for African Students with Symptoms of Low Mood During the Covid-19 Pandemic: A Qualitative Feasibilty Study
Authors: Ncheka Joyce Msumba , Menon J. Anitha , Davies E Bethan , Paul Ravi , Mwaba Sidney O C , Mudenda John , Wharrad Heather , Tak Harsa , Glazebrook Cris
Published: October 2023

Background
Online therapies have been shown to be effective in improving students’ mental health. They are cost-effective and therefore have particular advantages in low-income countries like Zambia where mental health resources are limited. This study aimed to explore the perceived impact of the COVID-19 pandemic and the feasibility of implementing an iCBT intervention (‘moodgym’) to improve resilience in vulnerable Zambian students.
Methods The study was a qualitative interview study. Participants identifying as having symptoms of low mood and completing a baseline, online survey (n=620) had the option to volunteer for a semi-structured interview to explore views about their experience of the pandemic and the acceptability and perceived benefits and limitations of using moodgym.
Results A total of 50 students (n= 24 female, n=26 male) participated in the study. One theme with 4 sub-themes, captured the severe emotional and social impact of the COVID-19 pandemic. A second, very strong theme, with 5 sub-themes, reflected the considerable negative effects of the pandemic on the students’ educational experience. This included the challenges of online learning. The third theme, with three subthemes, captured the benefits and acceptability of moodgym, particularly in terms of understanding the relationship between thoughts and feelings and improving academic performance.
The fourth theme described the technical difficulties experienced by students in attempting to use moodgym.
Conclusion COVID-19 caused fear and impacted wellbeing in vulnerable students and severely impaired the quality of students’ educational experience. The findings suggest that moodgym might be a valuable support to students in a low income country.
Multimodality Imaging of Medical Resins: a Comprehensive Research Catalog
Authors: Fu Weibo , Way Ashley , Hernandez Mauricio , Meyer Travis
Published: October 2023

Background:
Additive manufacturing describes the process of creating and printing three-dimensional products. In medicine, stereolithography remains one of the most commonly used additive manufacturing techniques. At present, few studies have sought to quantify the imaging properties of stereolithography resins, which would allow for standardization and streamlining of medical research in additive manufacturing. The aim of this study is to quantify and catalog imaging properties of commercially available FormLabs stereolithography resins via computer tomography, magnetic resonance imaging, and ultrasound.
Methods:
Fourteen unique stereolithography resins offered by Formlabs (Somerset, MA) were selected based on their clinical utility. Each resin was subject to a tri-modality investigation through computer tomography, magnetic resonance imaging, and ultrasound imaging. Image analysis was performed by two separate board-certified radiologists using the picture archiving and communication system. Results of this analysis were aggregated and organized onto data tables.
Results:
Of the fourteen resins evaluated by computed tomography, twelve were found to have radiological properties that were within one standard deviation (σ) of a known type of body tissue, in Hounsfield Units. When the same fourteen resins were evaluated by magnetic resonance imaging, little variability was observed between each resin in image intensity. Of the fourteen resins evaluated through ultrasound, imaging revealed little variability with no significant points of comparison with human tissue.
Conclusion:
Our investigation confirms that computed tomography is an ideal method for comparing imaging properties of stereolithography resins with those of human tissue. A comprehensive catalog of imaging properties for stereolithography resins allows clinical investigators to standardize future research studies, decreasing inter-observer variability and improving research outcomes for new devices and phantom models in medicine.
Up to 200% underestimation of cumulative methane emission from individual landfills uncovers tens of Tg of overlooked annual emission worldwide
Authors: Wang Yao , Yin Ke , Fang Mingliang , Guo Yuliang , Pi Xiaoqing , Wang Yijie , He Hongping , Lou Ziyang , Fei Xunchang
Published: October 2023

Landfill methane (CH4) emissions account for ~ 10% of all anthropogenic CH4 emissions globally, amounting to ~ 50 Tg/year. Contrasted by “top-down” atmospheric inversion results, the mainstream “bottom-up” emission inventories, which use the Intergovernmental Panel on Climate Change’s (IPCC) model, exhibit significant bias due to inaccurate a priori decay constant (k) estimations. We improved the k estimation method by incorporating composition- and environment-specific corrections, which are readily integrated into the IPCC’s model. We demonstrate that the accuracies of CH4 emission predictions are significantly improved by using the corrected k values, which are benchmarked against the atmospheric inversion results. We extend the emission estimations to landfills worldwide and reveal up to 209% underestimation in individual landfills and several tens of Tg/year of potentially overlooked CH4 emission globally. Our findings highlight the importance of prioritizing landfill CH4 emission monitoring and reduction as one of the most cost-effective mitigation options to achieve current climate goals.
From combinatorial maps to correlation functions in loop models
Authors: Grans-Samuelsson Linnea , Jacobsen Jesper Lykke , Nivesvivat Rongvoram , Ribault Sylvain , Saleur Hubert
Published: October 2023

In two-dimensional statistical physics, correlation functions of the O(N)O(N) and Potts models may be written as sums over configurations of non-intersecting loops. We define sums associated to a large class of combinatorial maps (also known as ribbon graphs). We allow disconnected maps, but not maps that include monogons. Given a map with nn vertices, we obtain a function of the moduli of the corresponding punctured Riemann surface. Due to the map’s combinatorial (rather than topological) nature, that function is single-valued, and we call it an nn-point correlation function. We conjecture that in the critical limit, such functions form a basis of solutions of certain conformal bootstrap equations. They include all correlation functions of the O(N)O(N) and Potts models, and correlation functions that do not belong to any known model. We test the conjecture by counting solutions of crossing symmetry for four-point functions on the sphere.
Fault diagnosis of low-speed heavy load super large rolling bearing based on deep learning
Authors: Li Simin , Wang Hongchao
Published: October 2023

The conventional eigenvalue alarm mode has a high rate of false alarm and missed alarm for the low-speed heavy load super large rolling bearing. Besides, the traditional signal processing method such as envelope spectral analysis is difficult to extract its fault characteristic frequencies, resulting in a high rate of false diagnosis and missed diagnosis. In order to solve the above problems, an intelligent diagnosis method for the low-speed heavy load super large rolling bearing based on deep learning is proposed. The proposed method mainly utilizes the strong robustness of deep learning algorithm to the quality of original vibration data in the field of fault diagnosis. Firstly, an effective signal acquisition scheme is designed to solve the problem that the signal characteristics of low-speed heavy load super large rolling element bearing are difficult to be acquired. Then, the collected data are randomly divided into training sets, verification sets and test sets by using data enhancement technology. Subsequently, input the divided training set samples into 1-dimensional convolution neural network (1DCNN) deep learning model for learning and training to construct the 1DCNN learning model and set network structure parameters. Meanwhile, the optimal training model is obtained by validating the updating effect of model parameters through validation set. Finally, the test data is input into the trained model to realize intelligent diagnosis. Effectiveness of the proposed method is verified by the vibration data of a wind power main bearing.
Response of two aquatic plant species to metallic nanoparticles and their potential for phytoremediation
Authors: Ebrahimbabaie Parisa , Smith Anthony , Zahran Elsayed M. , Jones James , Pichtel John
Published: October 2023

Certain plants have been identified with the capability to take up metallic and metal oxide nanoparticles (ENPs), thus suggesting their potential role in phytoremediation. The reported study evaluated the response of two aquatic plants, sedge (Carex rostrata) and cattail (Typha latifolia), on their exposure to Ag, ZnO, TiO2, BiVO4/Pd, and Cu2O/Pd nanoparticles over 15 weeks. Plant physiological responses (chlorophyll content, carbonic anhydrase (CA) activity, leaf area, production of new shoots, and root length) varied according to the plant species and ENP type. By week 15, sedge treated with BiVO4/Pd ENP had a high chlorophyll content and increased CA activity and leaf area compared to the control. In contrast, cattail had reduced chlorophyll levels and number of new shoots when exposed to exogenously applied BiVO4/Pd. Highest sedge chlorophyll content at week 15 was measured in the mixed-ENPs, Cu2O, and Ag (53.2, 35.8, and 32.7%, respectively, greater than the control). The ZnO ENPs were beneficial for sedge chlorophyll content, cattail shoot production and root length. The mixed-ENPs treatment imparted positive effects to several sedge properties (CA and new shoots) and cattail (chlorophyll, leaf area, and root length). Additional research is needed to assess the capabilities of different aquatic plant species to tolerate metal-based ENPs for remediation purposes.
The implication of Brexit on the financial market of the European Union and its regulation – legal and institutional aspects
Authors: Wicha Agnieszka
Published: October 2023

The Article tackled with the topic of the impact of Brexit on the EU financial market. The most important changes were identified and defined. Among different types of  implications the Author chose those which were important for the shape of the EU financial market. The Article identified all crucial changes in the EU law regulating financial market. In the Article there was the analysis of the single passport rule in the context of Brexit and the sability of equivalency mechanism in this context. The changes in BMR and EMIR implied by Brexit were analysed.
Migration Policy is Heading Down a Beaten Track. Comment on the Judgment of the European Court of Human Rights in the R.R. and others v. Hungary Case of 5 July 2021
Authors: Kun-Buczko Magdalena
Published: October 2023

In July 2021, the Grand Chamber of the European Court of Human Rights (ECHR) delivered a judgment in the R.R. v. Hungary case which perpetuates previous case law on obligations in providing migrants with international protection. The judgment is also of critical importance in view of the Common European Asylum System.  

The ECHR has confirmed that Hungary had failed to full its obligations in providing migrants with international protection especially when it comes to the length of time applicants were deprived of their liberty and the extent of the protection afforded to the pregnant applicant and her minors.
Психологические особенности несовершеннолетних преступников: возможности психологической диагностики
Authors: Степанюк Екатерина А.
Published: October 2023

В статье рассмотрен вопрос о психологических особенностях преступности несовершеннолетних. Актуальность обуславливается увеличением подростковых правонарушений одиночно и в группах и необходимостью психологической работы по их профилактике. Несовершеннолетние правонарушители – это большая проблема в нашем обществе. Они могут стать угрозой для окружающих и самих себя, а также могут стать причиной социальных проблем. В разделе «Теоретическое обоснование» автор анализирует типы несовершеннолетних преступников, объективные и субъективные причины преступлений, факторы и условия причин, из-за которых подросток может встать на путь правонарушений и как формируются различные подростковые преступные и противоправные группировки. Рассмотрен вопрос как влияет организация досуга детей и подростков на формирование системы жизненных ориентаций и что из этого следует. Были обозначены основные методы по выявлению подростков «группы риска», которые были созданы такими исследователями как: Сурикова, Кеттел, Кук-Медлей, Орел и др. Методы направлены для диагностики определения личности, склонности к различным формам девиантного и саморазрушительного поведения, поиска ощущений, враждебности, поведения в трудных ситуациях. Рассмотрены способы профилактики в работе с ними, включая комплексы мер для данного мероприятия и способы профилактики групп. В разделе «Обсуждение результатов» автор приходит к выводу о том, что молодые люди, не являющиеся зрелыми личностями, имеют большую податливость на манипуляции преступных группировок и взрослых, которые занимаются преступлениями. Понимание психологических особенностей несовершеннолетних преступников является важным шагом в борьбе с подростковой преступностью. Необходимо оказывать систематическую помощь детям и подросткам, которые подвержены риску встать на путь правонарушений, а также создавать условия для предупреждения таких ситуаций. Поскольку данная проблема остается одной из наиболее актуальных в нашем обществе, работа с ней должна быть постоянной и всесторонней.
Межличностная интолерантность к неопределенности взрослых детей в связи с особенностями стиля воспитания матери
Authors: Найденова Елизавета В.
Published: October 2023

Введение. В статье изучается вопрос наличия взаимосвязи между интолерантностью к неопределенности взрослых детей и особенностями воспитания, которые демонстрировали их матери. В современном мире множество людей сталкиваются с различными стрессовыми ситуациями и вызовами, связанными с изменениями в работе, взаимоотношениями, повседневной жизнью. Неопределенность и неясность в стрессовых ситуациях могут вызывать тревогу и эмоциональное напряжение, что сказывается на межличностном взаимодействии, приводя к конфликтам или отдалению людей. В связи этим является важным выявление возможных детерминант формирования межличностной интолерантности к неопределённости. В работе впервые изучается вопрос наличия влияния стиля материнского воспитания на формирование особенностей восприятия их детьми неоднозначности в межличностном взаимодействие. Методы. Выборку исследования составили 100 респондентов в возрасте от 18 до 25 лет. 1. В исследовании были применены следующие методики: авторский опросник по выявлению директивного стиля воспитания и гиперопеки в детстве и юношестве, опросник «Подростки о родителях» в адаптации Вассермана, Горьковой, Ромициной (2004), Новый опросник толерантности к неопределенности Корниловой (2010). Результаты. Показано наличие значимых взаимосвязей между показателем межличностной интолерантности к неопределенности и враждебностью, а также непоследовательностью в воспитании, которые применяли матери респондентов. Также были обнаружены значимые различия в показателях межличностной интолерантности к неопределенности у исследуемых с высокими и низкими показателями гиперопеки. Обсуждение результатов. Существует преемственность интолерантности к неопределенности и влияние особенностей социальных контактов на её формирование. Нетолерантные к неопределенности матери могут применять специфические для них способы воспитания детей, формируя при этом у них межличностную интолерантность к неопределенности. В заключение автор приходит к выводу о вероятном влиянии враждебности, непоследовательности и гиперопеки матери на проявление у её уже выросших детей нетерпимости к неопределенности в межличностных отношениях.
Социальная активность студентов в университете: ее проявления, значение и взаимосвязь с коммуникативными навыками и установками
Authors: Вашумирская Дарья В.
Published: October 2023

Введение. Социальная активность в рамках университетской жизни включает в себя совокупность отношений студентов, задействованных в образовательном процессе, научной деятельности, внеучебных мероприятиях, самоуправлении и межличностном общении. Актуальность изучения социальной активности обусловлена современными реалиями: общество справляется с последствиями пандемии, а университеты перешли из дистанционного в очный формат обучения. Изучение роли социальной активности в учебной деятельности позволит ответить на вопрос: «Нужно ли мотивировать студентов на общение и активную социальную жизнь?».  Цель исследования – определить влияние социальной активности студентов на их успешность в ученой деятельности. Методы. В исследовании приняли участие 75 студентов в возрасте от 17 до 24 лет. Нами было использовано авторское анкетирование, направленное на определение сходства и различия между социально активными и менее социально активными студентами. Для изучения различий между ними были выбраны следующие методики: «Диагностика типа коммуникативной установки» и «Коммуникативные и организаторские склонности (КОС)». Обработка эмпирических данных проводилась с помощью математической статистика (количественный анализ, корреляционный анализ по Спирмену). Результаты. Были выявлено, что общение с другими студентами влияет на чувство принадлежности к университету, и на учебную успеваемость. Степень общения оказалась отрицательно связана с общим уровнем негативных установок и положительно с уровнем коммуникативных навыков. Обсуждение результатов. В ходе анализа исследований установлено, что социальная активность студентов положительно влияет на их успеваемость в учебе, а также на их чувство принадлежности к университету. Можно сделать вывод, что необходимо способствовать студенческой социальной активности в рамках университетской жизни с помощью улучшения коммуникативных навыков студентов.
Review on PCSK9: A Pertinent Therapeutic Target in Cardiovascular Disease
Authors: Singh Sonia , Jha Manas Kumar
Published: October 2023

A Proprotein convertase subtilisin/kexin type-9 is considered a zymogen, extensively
found in the liver. PCSK9 is found in circulation in the plasma, where it attaches to low-density
lipoprotein (LDL) receptors on the cell surface, is internalized, and subsequently directs the receptors
to be degraded by lysosomes. Investigations of naturally or organically found PCSK9
gene variations, which generated high levels of plasma LDL cholesterol deviations and varied
atherosclerosis proportion factors, released floods of pharmaceutical along with biological and
live sciences research into the world. Significant advances in our understanding of the physiological
control of PCSK9 led quickly to the development of biological inhibitors of PCSK9 that are
now available for purchase. These inhibitors decreased LDL cholesterol levels with other improved
cardiovascular outcomes. The current manuscript will show the rapid development of
PCSK9, beginning with its discovery as a novel gene and progressing through its use as a therapeutic
target, followed by its testing on animals and humans and, eventually, its use in outcome
trials and clinical applications.
Abusive use of Zolpidem as a Result of COVID-19 and Perspectives of
Continuity of the Problem in the Post-Pandemic Period
Authors: de Lima Wesley Dawison , da Silva Michael Douglas , de Souza Costa Eurico , Pinheiro Francisco Irochima , de Azevedo Eduardo Pereira , Cobucci Ricardo Ney , de Paiva Cavalcanti José Rodolfo Lopes , Guzen Fausto Pierdoná
Published: October 2023

Zolpidem is a non-benzodiazepine hypnotic drug that works as a positive modulator of
Gamma-Amino Butyric Acid-A (GABA-A) receptors, with high selectivity for α1 subunits. Given this
selective binding, the drug has a strong hypnotic activity. Social isolation during the SARS-CoV-2
pandemic has contributed to increased rates of anxiety, depression, and insomnia. As a result, studies
have pointed to a possible increase in the indiscriminate use of drugs with sedative effects, such as
Zolpidem, during the pandemic. The aim of this work was to present prospective evidence that warns
of the possibility of the abusive use of Zolpidem even after the pandemic. High rates of addiction to
this drug have been reported around the world after the emergence of the coronavirus. Data from the
National Survey on Drug Use and Health and from Medicaid support the continuing growth in prescription
and indiscriminate use of Zolpidem during the pandemic and afterward. Therefore, there is
enough evidence to support the indiscriminate use of this drug since the beginning of the pandemic.
Rates of indiscriminate use of sedatives may continue to increase in the post-pandemic period, especially
if strict control measures are not taken by health authorities.
A review on Punarnavadi Kwath : An Ayurvedic polyherbal formulation for Chronic Kidney Disease (CKD)
Authors: Santosh Panwar  , Ram Kishor Joshi  , Udai Raj Saroj
Published: October 2023

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural abnormalities, or impaired excretory renal function suggestive of a loss of functional nephrons. Most patients with CKD are at risk of accelerated cardiovascular disease and death. Punarnavadi Kwath is a formulation, which contains nine medicinal plants viz. Boerhavia diffusa, Barberis aristate Dc. Curcuma longa, Zingiber officinale Roxb, Terminalia chebula Retz. Tinospora cordifolia (Willd.), Plumbago zeylanica Muell Arg, Clerodendron serratum, Cedrus deodara (Roxb) Loud. These herbs have the potential to treat symptoms of CKD like inflammation and pain other than that, the goal of treatment is to improve kidney function, reduce symptoms and prevent complications. This review paper emphasized on a comprehensive information for each herb of Punarnavadi Kwath because pharmacology, mechanism of actions based on various preclinical studies, safety precautions along with the current research potential of the herb. At the same time, the probable pharmacodynamic action of drugs is drawn to know the imperative for optimal and safe utilization of the herb, are discussed in this review paper.
Critical review of the utilization of Panchagavya in the form of Nutraceuticals
Authors: Vasavi Totawar (Madurwar)
Published: October 2023

Background: In India Cow represents Mother Earth and is commonly called as ‘Gaumata’ because of its nourishing nature. In Ayurveda, since ancient time’s cow products have been used for a healthy body, therapeutic purposes and pharmaceutical processes. Panchagavya is a mixture prepared by using five ingredients derived from Cow. The three direct ingredients are cow dung, cow urine and cow milk and the two derived products are ghee and curd each of which represents ‘Gavya’ i.e., obtained from Gou (Cow). Each Gavya can be used individually or in combination with other products.  Any product generated from food sources having additional health advantages in addition to the essential nutritional content contained in foods is considered as a Nutraceutical. The long standing consumer acceptability of nutraceuticals is brought about by their association with conventional medicine. Although the idea of nutraceuticals has grown in popularity recently, it has its roots in the traditional Ayurvedic medicine of ancient India. Aims and Objectives: This work is a modest attempt to employ Panchagavya as a kind of nutraceutical.  Materials and Methods: Various books and review articles were referred to carry out this review. Results and Conclusion:  A number of illness, including obesity, dietary and gastrointestinal tract abnormalities, leucoderma, wound healing, leucorrhoea, hepatitis, TB, ulcer, chemical intoxication, as well as other bacterial, fungal and viral infections, are advised for Panchgavya therapy. Nutraceuticals are substances that have physiological benefits or provide protection against chronic diseases. Using this concept, Panchgavya can be used as a kind of nutraceutical.
Infertility related to tubal factor and its management in Ayurveda
Authors: Piyusha Pandey  , Shikha Sharma
Published: October 2023

Infertility is defined as a failure to conceive with in one or more year of regular and unprotected coitus. Many causes are responsible for female infertility in which 30- 40% case are related with tubal blockage.[1] Fallopian tubes are very important structure of Artavavaha Srotas as they carry Bija Rupi Artava. Bija undergoes fertilization process within the fallopian tube. Due to tubal blockage Bija and Shukra are not able to meet in fallopian tube and it hampers process of fertilization and female does not able to conceive. Ayurveda has been successful in treating infertility since several thousand years. If we emphasize on tubal blockage according to Ayurvedic aspects we find that it occurs due to Vatakapha dominated Tridoshaj condition as Vata is responsible for Samkocha, Kapha for Shopha and Pitta for Paka. So, in Ayurvedic management we do local treatment in the form of Uttar Basti with certain drug which has property of Vatakaphanashaka and Tridoshaghna and it could remove the blockage by reaching up to the minute channels.
A review on importance of Rajaswala Paricharya
Authors: Raihana Ahmed Choudhury  , Yanbeni Humtsoe
Published: October 2023

Women in the reproductive age group experience a variety of conditions related to the menstrual cycle, such as menorrhagia, dysmenorrhea, irregular menses, PCOD, endometriosis, etc., which seriously affect their health and happiness as well as being extremely detrimental. It also increased the prevalence of infertility. As a result, there is a pressing need to educate the public, regarding the numerous Paricharyas (ways of living) recommended by Ayurveda to keep the Doshas in balance, which maintains health in turn. Ayurveda advises women to adhere to "Paricharyas" conduct that should be followed at various stages of life, such as Rajaswala, Garbhini, and Sootika, in order to improve their health and quality of life. The Rajaswala Paricharya is the one that receives the least attention. This subject was chosen because it was noted that modern science has described fatigue and lower abdomen pain as having an impact on the menstrual cycle and its related symptoms, although Ayurveda has not specified such symptoms.
Sharir Kriyatamak study of role of Rakta Vridhi in Vyanga and its treatment with Asriksravnam Purva Baladi Lepam
Authors: Sourabh Sharma  , Manu Sharma  , Aakriti Jamwal
Published: October 2023

Background: In Ayurveda all skin ailments are mostly mentioned in Kustha and Kshudra Roga. The disease Vyanga is a type of Kshudra Roga. It may manifest with various sign and symptoms like Mandalam Visrijati, Niruja, Tanu, Shyava lesion over face. In the pathogenesis various Nidanas like Krodha, Shoka, Shrama etc. are responsible for disease Vyanga. In Ayurveda, for the treatment of this disease so many remedies as internal and external applications, Shodhana therapy like Raktamokshana are described. Aim: Sharir Kriyatamak study of role of Rakta Vridhi in Vyanga and its treatment with Asriksravnam Purva Baladi Lepam. Study design: The Study was single arm, open clinical trial. Sample size: Total number of patients taken for the study was 30 excluding dropouts. Intervention: Asriksravnam followed by local application of Lepa consisting Bala, Atibala, Madhuka, Haridra. Procedure was repeated after every 7 days for 10 sittings. Duration: 70 days Follow up: After every 7 days following procedure. Observations and Results: The observations recorded in the clinical trials were assessed and results were drawn which shows the treatment given to the patients. Overall response is found to be significant for some parameters. Conclusion: Clinical response of the treatment Asriksravnam Purva Baladi Lepam have given best results for parameters like Daha, Kandu, Shyava Varna.
Ayurvedic management of Ruddhapatha Kamala (Obstructive Jaundice) - A Case Study
Authors: Bhargav HM  , Madhava Diggavi  , Puja Yadav
Published: October 2023

Biliary obstruction[1] refers to blockage of any duct that carries bile from the liver to the gallbladder or from the gallbladder to the small intestine. The clinical setting of the failure of biliary flow may be due to obstruction by mechanical means or by metabolic factors in the hepatic cells. The discussion of metabolic causes of biliary obstruction is very complex; the pathogenesis is not always clearly defined. While on the other hand, the condition Ruddha Patha Kamala in Ayurveda is the nearest possible clinical correlation to biliary obstruction wherein the flow of Pitta is obstructed by Kapha.[2] A structural / physical complete blockage of biliary flow needs a surgical intervention while if the cause is due to metabolic compromise or a partial block, the condition can be reversed effectively through Ayurvedic medications. Here is a case of obstructive jaundice, with a h/o cholecystectomy 20y back and H/O ERCP 5y back, treated successfully with Ayurvedic medications and some diet modifications for about 42 days. A combination of Avipatthikara Churna, Shweta Parpati, Yava Kshara and Katuki Churna was the intervention given. Mulaka Yusha twice a day along with bland diet was advised as Pathya. By the end of 42 days, the LFT report turned completely normal and the patient felt very healthy subjectively. There exists a need in the current times to critically understand the treatment techniques and principles of traditional medicine systems and to make use of them in treating certain conditions where the other conventional medicine systems fail.
An insight towards the Ayurvedic management of Trigeminal Neuralgia - A Single Case Report
Authors: Pooja Shivashimpar  , Prashanth AS
Published: October 2023

One of the unpleasant conditions affecting the fifth cranial nerve, trigeminal neuralgia causes extreme unilateral pain in the areas served by its branches, along with stiffness in the temporal mandibular joint. Anticonvulsants, tricyclic antidepressants, and other surgical procedures are used to treat trigeminal neuralgia in contemporary medicines Initial adverse effects that are frequently experienced are ataxia, diplopia, nausea, and drowsiness. According to ancient Ayurvedic texts, this condition is closely related to the Sannipatika disease Ananthavata. Even the name suggests that the Vatadosha is highly vitiated. Anantavata is one of the 11 varieties of Shirorogas described by Acharya Sushruta. The treatment is based on Tridosha. The goal of the current study is to determine how effective Ayurveda medicine in Trigeminal neuralgia.
Ayurvedic treatment regime of Ovarian Cyst: A Case Report
Authors: Deepika  , J.K. Panda  , Suniti Tanwar
Published: October 2023

Introduction: Ovarian cysts are fluid-filled sacs that develop on or within the ovaries, which are part of a woman's reproductive system. Most ovarian cysts are benign (non-cancerous) and do not cause any symptoms. However, in some cases, ovarian cysts can grow larger, rupture, become painful, or cause other complications. Hormonal contraceptives and Surgery only the treatment follow by modern system of medicine. A hormonal contraceptive contributes untoward effect. In Ayurveda it can be correlated with Granthi (Kaphaja Granthi). Methods: In this present case study, a 36 years old woman patient consulted to the OPD with the complaint of Pelvic pain come and go, Bloating in the abdomen, Changes in menstrual patterns, and Pain during sexual intercourse. She had also brought her ultrasonography (USG) and finding suggested a right ovarian complex cyst measuring 36mm×36mmx34mm. She was supposed to be treated with traditional ayurvedic formulations; the case was treated for three months with a combination of different traditional Ayurvedic drugs, with the goal of relieving symptoms and dissolving the ovarian cyst. This patient was treated with traditional Ayurvedic formulations like Varunadi Kashyam, Guggulu Panchapala Churnam, Dashmoola Kwatha, Ajmoodadi Choorna. Result: Only Ayurvedic medicines were used during the course of the treatment. Follow-up USG showed complete disappearance of cyst and symptoms also subsided to a great extent. Discussion: The present study emphasizes the role of Ayurveda in bringing a positive result in the management of ovarian cyst.
Efficacy of Shrungatak Modak and Jatifal Oil in Ksheenshukrata w.s.r. to Oligospermia – A Single Case Study
Authors: Sunil Sadashiv More  , Ashlesha Suresh Bankar
Published: October 2023

Infertility is defined as the failure of a couple to achieve a pregnancy with regular unprotected sexual intercourse after 12 months or more. A recent study status on Infertility states that, 50% is related to reproductive anomalies or disorders in the male, in which 90% of male infertility problems are related to Oligospermia and other abnormalities in semen analysis. However, there are number of treatments like hormonal therapies, intrauterine Insemination and test tube baby. Available but it is cost effective and not surety is there. That is the reason today to explore Ayuerveda are mediator to treat this type of condition. As per Ayurveda, Oligospermia can be considered as Ksheenashukra. In Ksheenashukra there is diminished level of Shukra in the infertile couples. In Auervedic texts many herbal preparations mentioned in management of Ksheenashukra. Here a Single case were taken to evaluate the effectiveness of Shrungatak Modak to treat a Ksheenashukra.
Management of Chronic Kidney Disease - An Ayurveda Case Study
Authors: Aggarwal Ankita , Sokiya Gracy , Sharma Gaurav
Published: October 2023

CKD has become a common disease with a high Prevalence rate of nowadays [1] in people including young individuals, with dialysis and renal transplant as its mainstream healing treatment, but due to low financial backgrounds among large percentage of individuals in India, everyone cannot afford to live a good quality of life. Hence, every individual is not a candidate for renal transplant or dialysis. So, to overcome this issue, an alternate has to be taken keeping in mind a healthy life which is the need of hour. CKD, i.e., Chronic Kidney Disease itself indicates chronicity with irreversible damage to the kidneys due to main leading factor in many cases nowadays as a major cause which is Hypertension and Diabetes mellitus type 2, which clinically presents as symptomless sometimes in initial stages and further presents with pedal edema, decreased appetite, nausea, difficulty in micturition/decreased urine output, frothy/foamy urine, fatigue.[2] Usually it is manifested through various lab investigations such as kidney function test in which increase in serum urea levels, serum creatinine and other are seen i.e., a waste product made by our muscles, also Kidney’s one of the vital function is production of erythropoietin[3] gets hampered due to underlying cause results in decline in Hb levels. So, to overcome this Punarnavadi Mandoor along with other were advised to the patient. Here the focus is on improvement in various Hematological levels before and after treatment of CKD, by giving Renogrit tablet, Punarnavadi Mandoor, Corighan Vati etc., having special effect on kidneys/as renoprotective.
Clinical efficacy of Jaloukavacharana (Leech Therapy) in Thrombosed External Haemorrhoids – A Case Study
Authors: Rakhy M  , Sreenath PS
Published: October 2023

Jalaukavacharana or Leech therapy is medicinal leech therapy which is used in a variety of inflammatory conditions. It is indicated in Raktaja and Pittaja Vikaras. Its mode of action depends on the injection of leech saliva into patient's tissues during the process of blood sucking. Leech’s saliva contains numerous bioactive constituent which possesses anti-inflammatory, analgesic, thrombolytic, anti-coagulant and blood circulation enhancing properties. Thrombosed hemorrhoid is an emergency condition that occurs due to high venous pressure associated with severe pain in the anus. In the present study a thrombosed external haemorrhoids is managed with Jaloukavacharana and its efficacy was observed.
Pharmacognostical and phytochemical studies on leaves of Tagetes erecta Linn.
Authors: Pankaj Chaudhary
Published: October 2023

Background: Tagetes erecta Linn. (Asteraceae) is a well-known plant for its antihypertensive, antioxidant, antidiabetic, aphrodisiac, and hepatoprotective properties. To investigate the pharmacognostic, physicochemical, and phytochemical determinations of this plant's leaves. Materials and Methods: The macroscopic characteristics of the leaves, such as size, colour, surface characteristics, texture, fracture characteristics, and odour, were studied pharmacognostically. The cellular characteristics of the drug were studied using a microscope on both the intact leaves and the powdered drug. According to WHO guidelines, extractive values, loss on drying (LOD), total ash, water-soluble and acid-insoluble ash, and moisture content of Tagetes erecta leaves powder were determined. For the various phytoconstituents, preliminary phytochemical screening and qualitative chemical examination studies have been conducted. Results: TLC analysis revealed the presence of alkaloids, glycosides, flavonoids, steroids, saponins, and tannins. Microscopic examination revealed the presence of xylem vessels, vascular bundles, and phloem fibres. Conclusion: To authenticate, standardise, and avoid adulteration in the raw material, pharmacognostical and preliminary phytochemical screening of Tagetes erecta leaves will be beneficial. The diagnostic microscopic characteristics and physicochemical data will aid in the creation of a monograph. The chromatographic fingerprinting profile can be used to standardise Tagetes erecta leaf extracts and formulations.
Motivations and challenges of women entrepreneurs: Experiences of small businesses in Dhangadhi City of Nepal
Authors: Bhatta Ghanshyam , Baijal Sanjay , Kannoujia Suman
Published: October 2023

Entrepreneurship is recognized as a crucial factor in the economic progress and poverty reduction of the world. It is a formidable engine of business activities that promotes innovation and takes advantage of new opportunities. The purpose of this paper is to investigate the motivations and challenges of women entrepreneurs in small business of Dhangadhi City Nepal. Descriptive research design is used and the data were analyzed using factor analysis and descriptive statistical tool. The study conducted on 50 women entrepreneurs of Dhangadhi city who were purposively selected and used structured questionnaire with the help of survey method. The profile of women entrepreneurs shows information about their age, marital status, cast, religion, education, types of business, sources of capital and types of family they belongs too. The results shows that among the various reasons for starting the business, motivated from friends is most significant factor to start the business to women entrepreneurs. Therefore, the trade exhibition and business meetings in local level should be encouraged. Regarding the motivating factors the self interest of women entrepreneurship is found important inspiring factor. Thus, the family members should encourage. Whereas, regarding the various challenges, the high level of competition in same nature of business is found major problem to them. Therefore, the business should be undertaken in new area with innovative ideas. Moreover, this study could be milestone for future researchers, policy makers, academician, owners and women entrepreneurs
Social Inclusion through Affirmative Action Programs under Corporate Social Responsibility: A Case Study of TATA Steel Limited
Authors: Chakraborty Utpal Kumar , . Vinamrta
Published: October 2023

The Indian economy is benefitted through the huge working age demographic dividend of India but this group of population also became the prime responsibility area for the Indian Government. Indian development is also subjected to criticism for widening the inequalities range. It has been said that to bring long term change in reducing inequality a country must worked upon its employment structure. For reducing the inequality many steps have been taken Indian government in order to boost up the social inclusion scenario. The Indian economy system is incomplete without its private sector and change in employment structure cannot be achieved without the help of the private sector companies. The private sector companies have also taken responsibility and working through affirmative actions in order to strengthen social cohesion and to bring social equity and economic development in India. Many Indian private sector companies have been working on special programmes focused on Scheduled Castes and Scheduled Tribes Communities youths skill development and entrepreneurship development through their Corporate Social Responsibility (CSR) programmes. This article is developed on the basis of secondary data sources and taken the case of TATA Steel Affirmative Action (AA) Policy and their CSR projects to show some of the best practices in India and its impact on social inclusion of the target groups on the chosen four heads of Employment, Employability, Entrepreneurship and Education under the affirmative action programme of TATA Steel. Although there is an increasing trend for the number of beneficiaries belonging to the Scheduled Caste (SC) and Scheduled Tribe (ST) community in TATA Steel CSR projects but their share in the workforce of TATA Steel is still not even one percent increase per year in last five financial year.
Ethical Aspects of the Assisted Biomedical Reproductive System with Special Attention to the Legislation of the Republic of Srpska
Authors: Jotanović Radenko , Miškić Mirjana
Published: October 2023

The achievements of modern medicine have expanded the range of controversial situations in doctrine and the practice of Family Law. A special ethical issue is concerned with parenthood as a result of assisted reproductive technologies. Many questions arise from this problem, such as the issue of who has the right to achieve parenthood through biomedical-assisted fertilization. Another important ethical question is: “Do children born this way have the right to know their biological origin?” Ultimately, the final question is whether biological and sociological parenting can be reconciled. How can this contradiction be resolved? The authors will try to give possible solutions to the mentioned problems considering solutions from comparative law and the needs of the current situation. All proposals de lege ferenda are given from the perspective of solutions and shortcomings of the family and reproductive legislation of the Republic of Srpska.
Animal Ethics and Aesthetics Revisited
Authors: Grušovnik Tomaž , Liponik Vesna
Published: October 2023

This paper aims to establish a different (transspecies) model of (animal) ethics by challenging one of the dominant paradigms of contemporary ethics (and aesthetics), namely the ethics of otherness. The ethics of otherness, striving for openness and the avoidance of appropriation, pushes the animal into representability and ineffability, marking it as “wholly other”, which consequently leads to the impossibility of any kind of communication and mutual understanding, even self-understanding. It is in this context that the problem of anthropomorphism arises, a problem that is crucially linked to the central issue that feeds the ethics of otherness, the fear of uncanny proximity. Our thesis is that the most appropriate path to resolving the problem is not to try to undo the irresolvable tension between distance and proximity (to find a way out of the confrontation with the animal, either through the logos or through something that is supposed to transcend the logos), but rather the deconstruction of these attempts at transcendence that are the root of the issue. The relationship with the other can then be understood from the recognition of this paradox, an intertwining of understanding and misunderstanding, distance and proximity, or distant proximity.
Overview of Animal Dehumanization in the Context of Changing Capitalism
Authors: Beroš Marin , Mandić Maja
Published: October 2023

Animals have been our companions since the beginning of time. Unfortunately, with each new civilizational “leap”, the gap between humans and animals widens. From the initial position of equality, we began to see animals as slaves, then as machines, and finally just as numbers. This relationship between animals and humans is gradually deteriorating, and the trend is particularly pronounced with the rise of industrial capitalism, as it exacerbated the “dehumanization” of animals, as well as the simultaneous “animalization” of humans. In that sense, the goal of this paper is modest - it seeks to draw attention to recurrent themes in the evolution of the animal-human relationship across history and to warn how the development of capitalism affects the same relationship. Furthermore, since at the beginning of the 21st century capitalism seems to be going through new fundamental changes, we think it is the right time to pose some questions on the future of this relationship.
Animals and Us, Us as Animals
Authors: Strahovnik Vojko
Published: October 2023

The field of animal ethics in philosophy has seen a variety of approaches since its recent resurgence. In this discussion, J. M. Coetzee’s book The Lives of Animals serves as a focal point. Two contrasting responses to Coetzee’s work are presented. The first response takes a traditional approach to the animal question, which aims to prevent suffering, improve animal welfare, and reject speciesism. The second response is more radical and emphasizes that the animal question is not just about animals, but also about us, human animals. This approach helpfully highlights the limitations of rational, philosophical thought when it comes to understanding the complexity of the animal question and ascribes the limitation to the phenomenon of the difficulty of reality.
Constructing the Infant Body: The Intervention of the Educated, Male Physician in Eighteenth-Century Infant Diet
Authors: Moore Alyssa
Published: October 2023

Drawing on medical advice literature, this paper examines the cultural history of the body in infancy in eighteenth-century England. This period saw the increasing professionalization of the medical field, particularly regarding children’s health, as an emerging profession of educated, male physicians sought to establish their exclusive authority on the medical market. As England’s medical market of the time was largely unregulated, these educated physicians competed with apothecaries, midwives, and female nurses for paying customers. Physicians argued that the disorderly, undisciplined nature of the infant body was incongruent with Enlightenment virtues, and therefore required a greater degree of medical management. Emerging out of this discourse were popular advice books which emphasized preventative measures in already-healthy infant patients. They were authored by a growing profession of educated, medical experts and were addressed to a lay audience of parents and child caretakers. This paper examines three immensely popular pamphlets authored by three physicians, Thomas Beddoes, George Armstrong, and William Cadogan. All three emphasized in their tracts the importance of maternal breastfeeding to the infant diet, citing Enlightenment ideals, humoral theory, and even the supernatural elements of breastmilk to support this claim. To bring the child body firmly under the control of the medical establishment, they argued that uneducated, lay practitioners, who were overwhelmingly female, received no formal education in the sciences and thus possessed little understanding of the nuances and complexities specific to the infant body. Parents were also incapable and deficient, at least to some degree, in the formal knowledge necessary to prevent illness in their infant children, and thus should rely on the physician’s expertise regarding the care of the infant body.