bluuebunny/crossref_metadata_2025 huggingface dataset:
PERLINDUNGAN HUKUM TERHADAP PEREMPUAN DAN ANAK AKIBAT KEKERASAN SEKSUAL DALAM LINGKUP KELUARGA DI INDONESIA
Authors: Diana Ayu Zeqwelin Ebestina
Published: September 2024

Perempuan dan Anak merupakan insan yang memerlukan perlindungan khusus karena lebih rentan terkena dampak kejahatan mengingat mereka adalah makhluk yang dianggap lemah dalam melakukan perlawanan terhadap kejahatan. Akhir-akhir ini, kejahatan terhadap anak dan perempuan meningkat khususnya dalam lingkup keluarga. Keluarga yang merupakan tempat pertama pertumbuhan bagi anak seharusnya memberikan jaminan perlindungan bukan malah menjadi tempat pertama yang memberikan trauma dan pengalaman buruk akibat kekerasan seksual. Banyak aturan hukum yang mengatur mengenai perlindungan hukum bagi anak dan perempuan namun apakah peraturan yang dibuat sudah cukup untuk menjamin perlindungan hukum bagi perempuan dan anak?. Kekerasan seksual dalam lingkup keluarga merupakan hal yang perlu disorot, untuk itu hukum harus terus menerus meningkatkan perannya dalam membasmi kekerasan seksual terhadap anak dan perempuan.
Unilateral facial asymmetry: Do not forget to look at the subcutaneous tissue
Authors: Yadav Vandana , Kumar Ishan , Yadav Nidhi , Aggarwal Priyanka , Verma Ashish
Published: September 2024

Parry–Romberg syndrome is a rare cause of hemifacial atrophy with associated other systemic complaints including neurological symptoms. Diagnosis is based on history and clinical examination supported by imaging. Here, we report a case of a 10-year-old female presenting with gradually progressive left hemifacial atrophy for 2 years and describe the clinical and imaging findings of the patient.
Cystic hemorrhagic intracranial metastasis in prostatic carcinoma
Authors: Gulati Vaibhav , Honarmand Amir Reza , Stachelek Gregory C.
Published: September 2024

Several patterns have been identified related to intracranial metastasis presentation of prostate cancers; however, their pattern of presentation remains controversial, and a broad consensus remains to be established. Cystic, hemorrhagic lesions, although rare, are an important identity for radiologists to be aware of. We present the case of a 59-year-old male with prostatic carcinoma who developed extra-axial hemorrhagic intracranial metastasis along with a brief review of literature.
PENGARUH LAMA PEMANASAN TERHADAP SIFAT FISIKOKIMIA DAN AKTIVITAS ANTIOKSIDAN EKSTRAK VCO DARI CAMPURAN KUNYIT, JAHE GAJAH, BAWANG PUTIH DAN DAUN SIRIH (THE INFLUENCE OF HEATING DURATION ON THE PHYSICOCHEMICAL PROPERTIES AND ANTIOXIDANT ACTIVITY OF VCO EXTRACT FROM A MIXTURE OF TURMERIC, GINGER, GARLIC, AND BETEL LEAF)
Authors: Wibowo Muhamad Agus , Pitri Sela Rahma , Ardiningsih Puji , Jayuska Afghani
Published: September 2024

The addition of spices to herbal oil increases bioactivity and physicochemical properties. Turmeric, ginger, garlic, and betel leaf are herbal plants that have the potential to enhance the antioxidant activity and physicochemical properties of herbal oil. This study aims to evaluate the effect of heating temperature on the phytochemical content, physicochemical properties, and antioxidant activity of VCO-based herbal oil with the addition of these spices. The research methods include phytochemical analysis, physicochemical analysis, and antioxidant activity testing using the DPPH method. The herbal oil was prepared at 100°C with a ratio of herbal plants to VCO of 4:30, and heating durations of 15, 30, 60, and 120 minutes were varied. The results show the presence of flavonoids, terpenoids, saponins, phenolics, and alkaloids in the herbal oil, while VCO contains flavonoids, terpenoids, saponins, and alkaloids, with the addition of herbal plants providing additional phenolic compounds. Physicochemical testing of the herbal oil formulations with heating durations of 15; 30; 60; and 120 minutes respectively shows water content of 0.0923; 0.0189; 0.0165; and 0.0123%, density of 0.98522; 1.02854; 1.55110; and 1.1227 g/mL, acidity level of 4.12; 4.80; 4.28; and 4.38, free fatty acid content of 0.0018; 0.0021; 0.00162, and 0.0029%, and peroxide value of 0.0021; 0.0035; 0.0035; and 0.0042 meq/kg. The IC50 value obtained from the antioxidant activity testing of the herbal oil formulation with a heating duration of 60 minutes is 577.3 ppm, while for VCO, the IC50 obtained is 1029.6 ppm. This indicates that the addition of spices and herbal plants can enhance the bioactivity of VCO-based herbal oil formulations. The addition of spices and herbal plants increases phytochemical content and antioxidant activity, but longer heating durations may decrease the physicochemical properties of herbal oil formulations
Macroscopic Assembly of Materials with Engineered Bacterial Spores via Coiled-Coil Interaction
Authors: Korbanka Lucas , Kim Ju-An , Sim Seunghyun
Published: September 2024

Herein, we report macroscopic materials formed by an assembly of engineered bacterial spores. Spores were engineered using a T7-driven expression system to display a high density of pH-responsive self-associating proteins on their surface. The engineered surface protein on the spore surface enabled pH-dependent binding at the protein level and enabled the assembly of granular materials. Mechanical properties remained largely constant with changing pH, but erosion stability was pH-dependent in a manner consistent with the pH-dependent interaction between the A-coils. Our finding utilizes synthetic biology for designs of macroscopic materials and illuminates the impact of coiled-coil interaction across various length scales.
Compensational Effects of 4-tert-Butylpyridine Additive for PTAA Hole Transport Material Using a Spontaneous Perovskite Passivator in Perovskite Solar Cells
Authors: Nishimura Naoyuki , Kanda Hiroyuki , Murakami Takurou N.
Published: September 2024

Development regarding hole transport material (HTM) plays an important role in the further development of perovskite solar cells (PSCs). Typical HTMs are organic semiconductors; therefore, dopants are required to enhance the hole collection properties of PSCs. One typical set of dopants used is lithium bis(trifluoromethylsulfonyl)imide (Li-TFSI) combined with 4-tert-butylpyridine (TBP). The primary role of TBP is to dissolve Li-TFSI, yet the effects of TBP independent of those of Li-TFSI remain elusive, especially when combined with poly[bis(4-phenyl)(2,4,6-trimethylphenyl)amine] (PTAA), a promising HTM possessing the advantage of thermal stability. To investigate the effects of TBP, we employed n-octylammonium TFSI (OA-TFSI) room-temperature ionic liquid (RTIL) additive for PTAA with a calibrated TBP concentration. The recently emerged OA-TFSI additive functions as a spontaneous perovskite passivator; during the deposition of the HTM solution containing the OA-TFSI additive, the OA cations spontaneously passivate the perovskite, effectively suppressing defects on the perovskite surface. As OA-TFSI is an RTIL, the necessity of TBP for dissolving OA-TFSI in the HTM solution is potentially negated, unlike Li-TFSI. Indeed, the OA-TFSI without TBP exhibited relatively high power conversion efficiencies (PCEs) in PTAA-based n–i-p-structured PSCs of up to 22.0%, exploiting the effective spontaneous perovskite passivation. However, TBP addition to the HTM solution resulted in compensational effects on the photovoltaic (PV) performance. TBP addition improved the uniformity of the PTAA HTM layer, contributing to an increased fill factor, and TBP addition presumably hampered spontaneous perovskite passivation and caused energy loss between the perovskite and PTAA, which decreased the open-circuit voltage. Consequently, the PSCs with optimal TBP addition exhibited a PV performance similar to that without TBP addition (e.g., highest PCE of 21.6%). The obtained insights provide valuable guidance regarding the use of additives for PTAA HTMs, which can be a bottleneck for PTAA-based PSC development, thus contributing to the further development of PSCs.
The Energetics of Electron Transfer in Redox-DNA Layers Mimics that of Redox Proteins
Authors: Zheng Zhiyong , Grall Simon , Kim Soo Hyeon , Chovin Arnaud , Clément Nicolas , Demaille Christophe
Published: September 2024

Redox-DNA layers have recently demonstrated unique properties, such as reorganization energy of electron transfer that can be tuned with DNA length or hybridization, and completely suppressed under nanoconfinement. These dis-coveries, attributed to the changes in the solvation of the redox marker and/or fast chain dynamics, provide a unique opportunity to use electrochemical measurements as a tool to address open questions in ion solvation and to clarify the origin of low reorganization energies reported in protein electron transfer. Here, high-scan-rate, variable-temperature cyclic voltammetry, analyzed using the Marcus formalism and molecular dynamics simulations, reveals that the total free energy barrier of electron transfer consists of two additive elements: the reorganization energy of the partially desolvated redox marker and the energy cost for solvation changes of the redox marker at the solid/liquid interface. These results may have profound implications for our understanding of electron transfer and solvation effects in fast-moving molecules, providing opportunities for better design of artificial photosynthetic systems, biosensing, and ener-gy conversion devices.
Competitive co-diffusion as a route to enhanced step coverage in chemical vapor deposition
Authors: Haridas Choolakkal Arun , Niiranen Pentti , Dorri Samira , Birch Jens , Pedersen Henrik
Published: September 2024

Molecules with a lower mass diffuse faster than heavier molecules in a mixture of gases at local thermodynamic equilibrium. We hypothesize that this phenomenon can be used to improve film uniformity and step coverage in chemical vapor deposition (CVD). Our concept is to add a heavy inert molecule as a diffusion additive to enhance the diffusion of the reactive gas species. We verify this by adding a co-flow of Xe in a thermal CVD process for boron carbide using a single source precursor. When adding a co-flow of Xe to the process we noted an increase in step coverage from 0.71 to 0.97 at 550 °C in 10:1 aspect ratio feature. The concept was further validated by depositing in lateral high aspect ratio chips with 500 nm gap height, rendering a penetration depth of about 25 μm with maintained material homogeneity into the structure. The results show that competitive co-diffusion with a heavy inert gas is a viable route to conformal CVD films.
DNA nanotechnology in the undergraduate laboratory: Toehold-less strand displacement in switchback DNA
Authors: Madhanagopal Bharath Raj , Chandrasekaran Arun Richard
Published: September 2024

Dynamic DNA nanostructures that reconfigure into different shapes are used in several applications in biosensing, drug delivery and data storage. One of the ways to produce such structural transformations is by a process called strand displacement. This laboratory experiment demonstrates a strand displacement reaction in a two-stranded DNA nanostructure called switchback DNA by the addition of a third strand. In this process, the difference in the affinity between the component DNA strands is used to convert switchback DNA into conventional duplex DNA. Students are introduced to the concept through gel electrophoresis and quantitative analysis of DNA nanostructure reconfiguration. The experiment presented here follows a series of DNA nanotechnology-based exercises in an undergraduate setting and is tailored for adaptation in a chemistry, biology, or biochemistry laboratory with minimal costs.
Closed-loop chemical recycling of a biobased poly(oxanorbornene-fused γ-butyrolactone)
Authors: Harsevoort Eva , Cioc Razvan , Lutz Martin , Thevenon Arnaud , Bruijnincx Pieter
Published: September 2024

New polymers, properly designed for end-of-life and efficiently formed from renewable carbon, are key to the transition to a more sustainable, circular plastics economy. Ring-opening polymerization (ROP) of bicyclic lactones is a promising method for the production of intrinsically recyclable polyesters, but most lactone monomers lack an efficient synthesis route from biobased starting materials, even though this is essential to sustainably account for material loss during the life cycle. Here-in, we present the exceptionally rapid and controlled polymerization of a fully biobased tricyclic oxanorbornene-fused γ-butyrolactone monomer (M1). Polyester P(M1) was formed in low dispersity (Đ = 1.2 – 1.3) and controllable molecular weight up to Mn = 76.8 kg mol−1, and exhibits a high glass transition temperature (Tg = 120 °C). The orthogonal olefin and lactone functionalities offer access to a wide range of promising materials, as showcased by post-polymerization modification by hydrogenation of the olefin, which increased polymer thermal stability by over 100 °C. Next to rapid hydrolytic degrada-tion and solvolysis, the poly(oxanorbornene-fused γ-butyrolactone) could be cleanly chemically recycled back to the mono-mer (CRM), in line with its favorable ceiling temperature (Tc) of 73 °C. The DFT-computed ΔH° of ring-opening with methanol of γ-butyrolactone-based monomers provided a model to predict Tc, and the DFT-computed and X-ray crystal struc-ture-derived structural parameters of M1, hydrogenated analogue M1-H2 and regioisomer M2 offered insights into the struc-tural descriptors that cause the high polymerizability of M1, which is key to establishing structure-property relations.
Transgender Erasure
Authors: Rehaag Sean , Verman Alex
Published: September 2024

This paper explores the experiences of transgender refugee claimants in Canada’s refugee status determination system by using mixed methods: quantitative analysis of data obtained from the Immigration and Refugee Board (IRB), reviews of published and unpublished decisions, country condition documentation packages and IRB guidelines, as well as interviews with refugee lawyers. Using these methods, we explore how credibility arises in transgender refugee claims, noting the impact of medicalization and country conditions materials on transgender claims, and drawing parallels between medical gatekeeping and credibility assessments in refugee claims. We identify potential explanations for low recorded numbers of transgender claims as rooted in data-gathering and decision-making practices that are misaligned with transgender experiences, and we offer policy recommendations to overcome this mismatch. Though transgender refugee claims appear to be largely successful in recent years, longstanding patterns of exclusion and erasure as policy nevertheless lead many transgender claimants to experience the refugee determination process as traumatic and transphobic, resulting in unaccounted-for complications and challenges to practice.
IDENTIFICACIÓN DE LOS FACTORES CLAVE PARA LA VIABILIDAD DEL EMPRENDIMIENTO FEMENINO PERMANENTE EN QUINTANA ROO
Authors: Hernández Beltrán Rocío , Espinoza Crisanto Deysi Del Rocío , Moreno García Blanca Verónica , Beltrán López Robert
Published: September 2024

El presente estudio tuvo como escenario de estudio la ciudad de Chetumal, Quintana Roo. El objetivo consistió en demostrar los principales motivos de los emprendimientos femeninos, las barreras a las que se enfrentan, así como las habilidades utilizadas durante este proceso. Para tal fin se realizó una investigación cualitativa con un diseño no experimental, a través de un cuestionario que respondiera las razones de emprendimiento, las limitantes y las estrategias que se emplean para alcanzar el éxito en sus negocios. Esta investigación responde que la principal razón de emprendimientos en las mujeres es la independencia y necesidad económica, aunado a esto los principales obstáculos son la falta de financiamiento, la corrupción y la cultura que demerita sus logros; sin embargo las mujeres emprendedoras destacan por utilizar estrategias que les permiten aminorar el impacto de dichas limitantes a sus negocios, tales como: la pertenencia a asociaciones, uso de tecnologías, colaboración y oportunidad a sus colaboradores. Por último, resalta la importancia de transmitir la idea de empoderamiento femenino a través del emprendimiento, dicho propósito representa para las emprendedoras un éxito alcanzado.
Artificial hard substrata from the Belgian part of the North Sea and their influence on the distributional range of species
Authors: Zintzen Vincent , Massin Claude
Published: September 2024

A comprehensive list of the macrospecies recorded on ten shipwrecks from the Belgian Part of the North Sea is presented. The historical records of these species in the area are also reviewed to address the potential role of shipwrecks in providing habitats for species typically associated with hard substrata. The current pooled species richness for Belgian shipwrecks consists of 224 spp., including 12 fish species. Among these species, 46 are new records to the Belgian fauna. Species on shipwrecks fulfil a gap in the regional distribution of sessile and mobile epibenthos. The records of several species are interrupted in the Southern Bight of the North Sea, simply because their habitats, natural hard substrata, are rare in this area and poorly studied. Another consequence of the presence of hard substrata offered by artificial sources is the increase in the distributional range of several species. Due to the presence of artificial substrata, a total of 12 southern species presented an extension of their known geographical range to the North.
Aphids on Ammophila arenaria in Belgium: first reports, phenology and host range expansion
Authors: Vandegehuchte Martijn L. , De la Peña Eduardo , Bonte Dries
Published: September 2024

Short notes don't have an abstract.
Transition Probabilities, Oscillator and Line Strengths in Sc XIX
Authors: Uddin Zaheer , Kaleem Muhammad , Javaid Saba , Zafar Roohi
Published: September 2024

Scandium XIX ion is a member of the isoelectronic sequence of Li-like ions. Numerical coulomb approximation and quantum defect theory have been used to calculate energies, quantum defects & transition probabilities, oscillator, and line strengths of Sc XIX ion for the transitions ns → mp, np → ms, np → md, and nd → mp Rydberg series. The energies of Sc XIXX ions up to n = 5 are given in the NIST database and the literature. We used quantum defect theory and determined the energies and quantum defects up to n = 30. The energies and quantum defects of 125 levels are reported for the first time. Sc XIX ion's transition probabilities, oscillator, and line strengths were compared with the corresponding values in the NIST database of spectral lines. The NIST database contains data of only seventy-six spectral lines. Only six spectra lines have percent uncertainties of more than 10%. The results of the remaining seventy spectral lines agree well with the NIST values. Almost 1800 transition probabilities, oscillators, and line strengths are new.
Computer Simulation of Adsorption of C60 Fullerene Molecule on Reconstructed Si(100) Surface
Authors: Urolov Ikrom Z. , Umarov Farid F. , Yadgarov Ishmumin D. , Rakhmanov Ganiboy T. , Jabborov Khayitmurod I.
Published: September 2024

The adsorption of the C60 fullerene molecule has been studied in various configurations on a reconstructed Si(100) silicon surface. Among fullerenes, fullerene C60 is of particular importance since it has the most stable form and consists of 60 carbon atoms. Monocrystalline silicon has the diamond structure, the size of its crystal lattice is 5.43 Å. The MD-simulation calculations have been performed using the open source LAMMPS MD-simulator software package and the Nanotube Modeler computer program. The Tersoff interatomic potential has been used to determine the interactions between the Si-Si, C-C and Si-C atoms. The adsorption energy of the C60 molecule on the reconstructed Si(100) surface, the bond lengths and the number of bonds formed depend on the adsorption geometry, i.e. at what point on the substrate the molecule is adsorbed and in what configuration.
Comparison of 2D and 3D p-n Junction Differential Conductance and Diffusion Capacitance
Authors: Dadamirzaev Muhammadjon G. , Kosimova Mamura O. , Boydedayev S.R. , Makhmudov Azamat S.
Published: September 2024

In the fabrication of 3D p-n junctions, doping or surface modification caused by ion injection changes the electrical properties and crystal structure of the semiconductor. In addition, as the size of the semiconductor device decreases, various quantum effects are gradually appearing in them. This shows that the scope of application of classical device theory is now limited. In recent years, two-dimensional (2D) materials with amazing atomically fine properties have attracted great interest. The electrostatic field properties of some 2D p-n junctions, such as WS2, MoS2, MoSe2, WSe2, and black phosphorus (BP), open the door to new possibilities for semiconductors. Changes in the diffusion capacitances and differential conductance’s of 2D p-n junctions under the influence of an microwave field, and the diffusion capacitances and differential conductance’s of 2D and 3D p-n junctions the change of conductivities under the influence of microwave field is compared.
Interactions of Amyloid Fibrils with Functional Proteins: Modulating Effect of Polyphenols
Authors: Trusova Valeriya , Tarabara Uliana , Gorbenko Galyna
Published: September 2024

The elucidation of interactions between functional proteins and amyloid fibrils is crucial for understanding the molecular basis of amyloid diseases, which are characterized by protein misfolding and aggregation. Polyphenols, due to their diverse biological properties, have garnered attention for their potential to modulate these protein-fibril interactions, thereby influencing disease progression and offering therapeutic possibilities. In this study, we investigated the effects of quercetin and its binary combinations with other polyphenols on the binding affinity between cytochrome c, in both its reduced and oxidized forms, and amyloid fibrils of insulin and apolipoprotein A-I. Our results demonstrate that quercetin complexation with cytochrome c decreases the binding affinity of insulin fibrils for both forms of the protein, while increasing the affinity for apolipoprotein A-I fibrils. This modulation was attributed to competitive or allosteric effects exerted by quercetin on cytochrome c. Additionally, while binary combinations of quercetin with other polyphenols did not reduce the affinity of insulin fibrils for oxidized cytochrome c, they did decrease the affinity in the case of reduced counterpart. These findings highlight the selective and significant impact of polyphenolic compounds on the interactions between amyloid fibrils and functional proteins, suggesting potential pathways for therapeutic intervention in amyloid-related disorders.
PENGEMBANGAN MEDIA PEMBELAJARAN STATISTIKA DAN PROBABILITAS BERBASIS APLIKASI ANDROID UNTUK MENDUKUNG PEMBELAJARAN HYBRID
Authors: Wicaksana Dinar Anggit
Published: September 2024

Pada masa new normal membuat pembelajaran hybrid menjadi salah satu yang wajib dimanfaatkan dalam melakukan transfer ilmu pengetahuan kepada mahasiswa. Berdasarkan hasil ujian statistika dan probabilitas semester genap tahun 2023 menunjukkan bahwa 55% mahasiswa menerima nilai cukup (C). Mahasiswa masih kesulitan dalam menganalisis uji hipotesis, analisis regresi dan korelasi. Penelitian ini bertujuan menghasilkan produk media pembelajaran statistika berbasis android yang dapat mendukung pembelajaran hybrid. Jenis penelitian ini adalah model Research and Development. Produk divalidasi oleh dua ahli yaitu ahli materi dan ahli media pembelajaran. Instrumen yang digunakan berupa angket dengan menggunakan skala likert. Diperoleh hasil validasi untuk produk media pembelajaran statistika mahasiswa teknik informatika universitas semarang adalah sebesar 3,35 dengan kategori sangat valid.
Physicochemical properties and radical scavenging activity of whey protein
hydrolysate by conjugation with lactose
Authors: Julmohammad N. , Roslan J. , Mohd Razali U.H. , Chin S.Y.
Published: September 2024

Whey protein isolate (WPI) was hydrolysed to whey protein hydrolysate (WPH) using
alcalase produced by Bacillus licheniformis at 65℃ for 3 hrs with an enzyme-to-substrate
ratio of 1:50. The WPI and WPH were then conjugated with lactose via Maillard reaction
by heating the solution at 95°C for different heating time which were 0 hr, 1 hr, 2 hrs, 3
hrs and 4 hrs. The objectives of this study were to characterise the physicochemical
properties (pH value, browning intensity, degree of glycation and Fourier transform
infrared spectroscopy) of conjugation of WPI and WPH with lactose and to analyse the
antioxidant activity of WPI and WPH after conjugation with lactose. The pH value and
degree of glycation of WPH-Lactose for all different heating times was higher compared
to WPI-Lactose. The antioxidant activity of WPH-Lactose conjugate was higher compared
to WPI-Lactose conjugate as shown in the analysis of ABTS+
radical scavenging activity
which was 2.37% for WPI-Lactose and 12.68% for WPH-Lactose that have been heated
for 4 hrs. However, the antioxidant activity of WPH was high even though without the
conjugation with lactose. Hence, findings showed that WPH can be used as a potential
ingredient for encapsulating bioactive compounds due to its high antioxidant activity.
Survival kinetics of Alicyclobacillus acidoterrestris spores in thermally processed
pineapple-mango blend juice
Authors: Md. Hazmi N.A. , Mahmud Ab Rashid N.K. , Abdul Karim Shah N.N. , Sulaiman A.
Published: September 2024

The presence of Alicyclobacillus acidoterrestris (AAT) spores in pineapple and mango
juices has been reported in the industry. Thermal resistance of AAT spores to
pasteurisation treatment poses a serious threat to the tropical juice industry. This study
investigates the influence of formulation (pineapple, mango, 70% mango-30% pineapple
and 50% mango-50% pineapple), total soluble solid (10 - 15°Bx), and pH (3.58-3.70) on
AAT (ATCC®49025TM) spores’ survivor after processing at 85 - 95°C. As the
temperature rises to 85℃ and 90℃, 1 log reduction of the spores was observed after
treatment for 5 mins. Spore concentration for each juice showed a sharp decrease when
the temperature reached 95℃, which resulted in a significant reduction (P<0.05) of 3 to 4
log CFU/mL. Significant reductions in pH and total soluble solids of juice samples were
noticed in all formulations and D-values of AAT spores heated at 85°C (14.1 - 16.6 mins)
were significantly reduced by double when heated at 90°C (5.8 - 6.7 mins) (P<0.05).
Weibull’s model shows a good fit to AAT spores thermal inactivation behaviour in
pineapple-mango juice blends tested in this study with the lowest value of Mean Squared
Error (MSE) and Accuracy Factor (Af) close to unity (0.07 ≤ MSE ≤ 0.48; 0.88 ≤ Af ≤
1.19) compared to first-order model (0.17 ≤ MSE ≤ 3.41; 1.07 ≤ Af ≤ 2.34).
Halal authentication: Fourier transform infrared spectroscopy and multivariate
calibration application for pork gelatin analysis in gummy candy
Authors: Supandi S. , Septiana A.D. , Kusumadewi N. , Fatmawati S.
Published: September 2024

Gelatin is a substance obtained from the partial hydrolysis of collagen, which is derived
from connective tissue, animal bones, and the skin of vertebrate animals, especially pork
and cows. Therefore, this study aimed to find out whether the gelatin contained in gummy
candy products in the Pasar Baru Bekasi is halal and not from pork. Fourier transform
infrared (FTIR) spectrophotometer was combined with principal component analysis
(PCA) and partial least square (PLS). The results of the score plot showed that the gelatin
of pork and cows was found in different quadrants. Samples 3 and 4 were in quadrant 3,
indicating similarities with bovine, while 1 and 2 were in their own quadrants, which
shows that they were not obtained from pork or beef. The multivariate regression curve
showed that the pattern of linear absorbance changes along with gelatin concentrations of pork and cows.
Usage of Psilocybin to Treat Huntington's Disease: A Research Protocol
Authors: Duan Cynthia , Farkhondehpay Navid , Safa Viana , Yuan Emma
Published: September 2024

Introduction: Huntington’s Disease (HD) is a progressive, neurodegenerative disease that causes significant amounts of neuron death in the brain. It is a genetic disorder, resulting from the over-repetition of the CAG sequence in the gene that codes for the huntingtin protein. Currently, there are no viable cures or treatments to slow or stop the progression of this disorder, making it a target candidate for treatment research. However, given the difficulty and complexity of in treating the genetic cause of HD in adults, a more viable approach may involve treating the resulting neurodegeneration with neuroprotective compounds, such as psilocybin. As such, our study proposes the usage of psilocybin to treat HD due to its neuroprotective, neurotrophic, and neuroplastic effects, resulting in a decreased rate of neuron loss and increased synaptic density. Methods: We propose an in-vivo experiment using several groups of zQ175 knock-in (KI) mice, which will mimic HD in the mice. Following 8 weeks, the mice’s brains will be extracted at different time intervals to analyze the progression of neuronal death using histology and immunohistochemistry, which should inform us about the progression of HD in the different groups of mice. Moreover, throughout this experiment, the motor control of the mice will be observed using the rotarod test, the raised beam test, and the footprint test. Data from these tests will act as behavioral markers for HD, providing an alternate source of information on the progression of HD in the mice. Expected Results: KI mice are expected to have lower rates of neuronal death, higher amounts of synaptic density, and higher scores on average across the three motor behavior tests, compared to the non-treated KI mice. Discussion: These results could provide insight into potential treatments for slowing the progression of HD. If successful, possible next steps could be to determine the efficacy of psilocybin in clinical trials for HD. Conclusion: This study is expected to provide information on the usage of psilocybin as a treatment for HD. If the expected results are obtained, psilocybin may help improve the quality of life for those afflicted with HD.
A Study on the Application of Audible Thinking Combined with Case Teaching Method in the Teaching of Nursing Room Visits for Trained Nurses
Authors: Luo Xiuying
Published: September 2024

Objective: To investigate the effect of using audible thinking combined with the case teaching method in the teaching of nursing checkups for regulation nurses. Methods: The period was April 2023–April 2024, and a randomized controlled group study was carried out in which 76 regulation nurses in our hospital were randomly divided into a research group and a control group, with 38 regulation nurses in each group. The control group used conventional teaching methods, and the research group used audible thinking combined with the case teaching method, comparing the two groups’ independent learning ability scores, assessment scores, and teaching satisfaction. Results: Independent learning ability score: after teaching, the research group was significantly higher than the control group (P < 0.05); Assessment results: the research group was considerably higher than the control group (P < 0.05); Teaching satisfaction: the research group was significantly higher than the control group (P < 0.05). Conclusion: The use of audible thinking combined with the case teaching method in the teaching of nursing room visits for trained nurses can improve independent learning ability and assessment results and increase teaching satisfaction.
The Effect of Predictive Nursing Intervention on Cardiac Function and Clinical Outcomes in CCU Patients with Acute Myocardial Infarction After Interventional Therapy
Authors: Wang Tingting , Xia Cui
Published: September 2024

Objective: To evaluate the impact of predictive nursing on the care of acute myocardial infarction (AMI) patients in the Coronary Care Unit (CCU) after interventional therapy. Methods: From September 2021 to September 2023, 84 AMI patients admitted to the CCU were randomly divided into two groups: the experimental group (42 patients) received predictive nursing, and the reference group (42 patients) received conventional nursing. Cardiac function and clinical outcomes were compared between the groups. Results: Before nursing, there was no difference in cardiac function between the two groups (P > 0.05). After nursing, the cardiac function of the experimental group was better than that of the reference group (P < 0.05). The clinical outcomes of the experimental group were better than those of the reference group (P < 0.05). Before nursing, there was no difference in psychological scores between the two groups (P > 0.05). After nursing, the psychological scores of the experimental group were lower than those of the reference group (P < 0.05). Conclusion: Predictive nursing can improve the cardiac function and clinical outcomes of AMI patients after interventional therapy and can also regulate patients’ negative psychological states.
The Predictive Value of NLR, IL-6, CRP, and PCT in Mycoplasmal Pneumonia with Complicated Myocardial Injury
Authors: Yang Yanping , Yang Lili , Nie Xueping , Li Wei , Chi Kangle
Published: September 2024

Objective: To evaluate the dynamic changes in neutrophil-to-lymphocyte ratio (NLR), interleukin-6 (IL-6), C-reactive protein (CRP), and procalcitonin (PCT) levels in children with Mycoplasma pneumoniae pneumonia (MPP) complicated by myocardial injury and to determine their predictive value both individually and in combination. Methods: 150 children diagnosed with MPP at Jiujiang Maternal and Child Health Hospital between June 2023 and June 2024 were selected. Patients were divided into the myocardial damage group (MD group, n = 65) and the non-myocardial damage group (non-MD group, n = 85), based on the presence of myocardial injury. Ninety hospitalized children without MPP served as the control group (Con group). Myocardial enzyme profile indicators, including lactate dehydrogenase (LDH), α-hydroxybutyrate dehydrogenase (α-HBDH), aspartate aminotransferase (AST), high-sensitivity cardiac troponin I (hs-cTnI), creatine kinase (CK), and creatine kinase-MB (CK-MB), were measured using a chemiluminescent immunoassay analyzer. Serum NLR, IL-6, CRP, and PCT levels were determined using appropriate analyzers. The correlation between these markers and myocardial enzyme indicators was analyzed using Spearman correlation analysis. Multivariate logistic regression was applied to identify risk factors for myocardial injury in MPP patients. Results: Serum levels of NLR, IL-6, CRP, and PCT in the MD and non-MD groups were significantly higher than in the Con group (P < 0.05), with the MD group showing higher levels than the non-MD group (P < 0.05). These markers were positively correlated with myocardial enzyme indicators. Logistic regression identified elevated NLR, IL-6, CRP, PCT, LDH, α-HBDH, AST, hs-cTnI, CK, and CK-MB as risk factors for myocardial injury in MPP patients (P < 0.05). Conclusion: Elevated levels of NLR, IL-6, CRP, PCT, and myocardial enzymes are significant risk factors for myocardial injury in children with MPP, offering valuable insights for prevention and prognosis.
Pengaruh Green Product dan Green Marketing Terhadap Keputusan Pembelian Produk the Body Shop
Authors: Aprilia Nur Aini Iftinia , Widiawati Diah , Hardiani Sunaryati
Published: September 2024

The purpose of this study is to examine how the influence of green products influences purchasing decisions, how the influence of green marketing influences purchasing decisions, the simultaneous influence of green products and green marketing on purchasing decisions, and which of the green products and green marketing has a greater influence on purchasing decisions using a sample of 100 people. Respondents were drawn from the female population of Malang who had purchased items from The Body Shop. Random sampling technique is used for sampling. Multiple linear regression analysis is used in data analysis to test hypotheses and produce green product has a positive and significant impact on purchasing decisions, green marketing has a positive and significant impact on purchasing decisions, green product and green marketing both have a positive and significant impact on purchasing decisions, green product and green marketing both have a positive and significant impact on purchasing decisions, and green marketing has a dominant influence on purchasing decisions.
Purchasing Intension: Effect of Shopee Paylater and Shopee Loans Features
Authors: Sugito Pudjo , Yulehinin Firsty , Kamaluddin Kamaluddin , Nirwana Nirwana
Published: September 2024

The aim of this study was to investigate how shoppe paylater and shoppe loan features affected purchasing intent. To determine which of the two independent research factors had the greatest influence on purchasing interest. This study's population consists of Merdeka University Malang students. To acquire primary data, a simple random sample procedure was applied. There were 80 students who responded. The primary data was also analyzed using the structural equation model-SmartPLS. According to these findings, the Shopee Paylater and Shopee Loans features have a significant impact on purchase intention both partially and simultaneously. Interestingly, shopee loans have a dominant effect on purchasing decisions. However, the research findings still require external validity by conducting other studies with different populations to generalize the findings more broadly.
Peran kepemimpinan transformasional, komitmen organisasi dan budaya organisasi terhadap kinerja pegawai
Authors: Hikmah Lailatul , Mujaya Alivia , Triatmanto Boge
Published: September 2024

This research aims to analyze the role of transformational leadership, organizational commitment, organizational culture on employee performance at the Malang City P3AP2KB Social Service. The data collection technique used a questionnaire with a sample of 60 respondents who worked at the Malang City P3AP2KB Social Service. The analytical tool used is the multiple linear analysis test. The results of the description of a picture in this study state that the independent variable transformational leadership has the highest score (mean) across all indicators of the other independent variables with more agree answers. In this way, the transformational leadership of the Malang City P3AP2KB Social Service has been very good and achieved. The results of the analysis in this study show that transformational leadership, organizational commitment, and organizational culture have a significant effect on the performance of Malang City P3AP2KB Social Service employees. Organizational commitment has a dominant influence on employee performance at the Malang City P3AP2KB Social Service.
Luxury Vehicle Enthusiast: A Customer Loyalty Analysis in Jakarta
Authors: Amelia Tifa Noer , Manungsong Swastika Feranti , Jahja Adi Susilo
Published: September 2024

This study aims to determine whether customer relationship management, public relations, and experiential marketing can affect customer loyalty. This study was conducted on luxury vehicle consumers in Jakarta. The study used a random sampling of 200 respondents. The research analysis technique is multiple linear regression using SPSS software. The results show that in both partial and simulant tests the model shows that customer relationship management, public relations, and experiential marketing effectively predict consumer loyalty. These findings show that the character of Jakarta as the capital city and the center of development in Indonesia impacts creating loyalty based on field assessment. About 50% of other variables need to be tested to strengthen factors that increase loyalty and show luxury vehicle enthusiasm in Jakarta. This research specifies an automotive distributor in Jakarta that specializes in luxury vehicles. Unlike the common vehicle customer, it is more manageable to maintain customer enthusiasm for luxury cars based on customer relationship management, public relations, and experiential marketing strategy.
Menguji Likuiditas dan Leverage: Dampaknya terhadap Financial Distress dan Firm Value di BEI
Authors: Limonu Rayhandani , Monoarfa Mohamad Agus Salim , Dungga Meriyana Franssisca
Published: September 2024

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh Likuiditas dan Leverage terhadap Financial Distress dan Firm Value (Studi pada Perusahaan Sektor Transportasi yang terdaftar di BEI Periode 2018-2022). Teknik pengambilan sampel dalam penelitian ini menggunakan teknik purposive sampling, Adapun populasi dalam penelitian adalah seluruh perusahaan sektor transportasi yang terdaftar di Bursa Efek Indonesia selama 5 periode sehingga diperoleh sampel sebanyak 110 sampel. Jenis data yang digunakan adalah data sekunder dan teknik analisis data menggunakan metode Two Stage Least Square (2SLS) dengan bantuan program SPSS 26. Berdasarkan hasil penelitian dan analisis data menunjukkan bahwa Likuiditas dan Leverage secara parsial dan simultan berpengaruh terhadap Financial Distress. Likuiditas, Leverage dan Financial Distress secara parsial dan simultan berpengaruh terhadao Firm Value.
Financial Performance: A Study of CAR and FDR Impact on ROA in Indonesian Islamic Banks
Authors: Sulistyorini Ery , Sarasmitha Citra , June Cindy Getah Tresna , Jauhari Burhanuddin
Published: September 2024

This research analysis the influence of CAR and FDR on ROA in Sharia Banks during the COVID-19 Outbreak. The phenomenon behind this research is global economic uncertainty due to the pandemic which affects the stability and financial performance of banks, especially Islamic banks. There is a research gap in understanding how financial variables such as CAR and FDR affect ROA in the midst of crisis conditions. This research uses financial report data from Islamic banks in Indonesia during the pandemic period, and the analysis method uses multiple regression. The research results show that CAR and FDR have a significant influence on ROA. These findings indicate that Islamic banks need to maintain and increase CAR and manage FDR well to maintain healthy financial performance. The discussion in this research emphasizes the importance of increasing capital, optimizing financing, and strict regulatory supervision as policy steps that can be implemented. Thus, this research makes an important contribution to the Islamic finance literature and provides practical recommendations for Islamic bank management and regulators to maintain financial stability and health in times of crisis.Keywords: Capital, profitability, sharia banking, COVID-19 pandemic.
Analisa Rencana Anggaran Pelaksanaan terhadap Rencana Anggaran Biaya pada Pekerjaan Struktur Bawah Proyek Rumah Sakit Universitas Surabaya
Authors: Kinasih Adristi Lintang , Sucipto Sucipto
Published: September 2024

Biaya merupakan faktor krusial dalam seluruh tahapan proyek konstruksi. Estimasi biaya perencanaan sangat penting dalam manajemen biaya. Kontraktor menghitung RAB dengan perkiraan biaya satuan 𝑚2 di lapangan, sedangkan biaya yang digunakan kontraktor di lapangan selama pembangunan proyek disebut RAP. Tujuan penelitian yaitu untuk mengevaluasi perbandingan antara RAB dengan RAP proyek Rumah Sakit Universitas Surabaya, dengan metode membandingkan pengalaman selama proses lelang dengan analisis koefisien berdasarkan gambar kerja dan upah borongan dari data RAP, AHSP dan kurva S. Hasil analisis menunjukkan RAP lebih rendah daripada RAB, dengan selisih 8,12%. Hal ini mengindikasikan potensi pengeluaran yang melebihi estimasi awal dalam tahap perencanaan proyek dan diperlukan evaluasi oleh stakeholder terkait untuk meninjau kembali strategi anggaran dan pengelolaan sumber daya guna maksimalkan penggunaan dana dan kelancaran proyek.
Analysis of Heavy Equipment Productivity in the Solo - Yogyakarta - NYIA Kulon Progo Toll Road Construction Project Section 1 Package 1.1
Authors: Ayu Kurniawati Shevi Adelia , Putra I Nyoman Dita Pahang
Published: September 2024

Proyek jalan tol Solo - Yogyakarta - NYIA Kulon Progo terletak di Jawa Tengah yang melewati pemukiman penduduk setempat, sehingga akses kendaraan alat berat akan terbatas. Penelitian ini bertujuan untuk mengetahui spesifikasi dan produktivitas alat berat pada STA 14+000 - 15+000 dengan menggunakan metode deskriptif kuantitatif. Alat berat yang diteliti adalah excavator, dump truck, bulldozer, vibratory roller, sheep foot roller, dan motor grader. Setelah dilakukan perhitungan, hasil produksi alat per jam adalah sebagai berikut: dump truck 3,56 m3/jam; excavator 65,94 m3/jam; bdozer 468 m3/jam; vibratory roller 105,67 m3/jam; sheep foot roller 105,67 m3/jam; motor grader 156,61 m3/jam. Durasi pekerjaan galian tanah adalah 58 hari, pekerjaan timbunan tanah 60 hari, dan pekerjaan geotextile dan timbunan LPA 60 hari dengan total durasi yang dibutuhkan untuk pekerjaan tanah adalah 178 hari atau 5,9 bulan 2 hari lebih cepat dari waktu yang direncanakan.
Economic Feasibility Analysis Based on Optimal Cash Flow Planning on the A. Road Construction Project
Authors: Mahrusah Safira , Putra I Nyoman Dita Pahang
Published: September 2024

Capital resources play an important role in a project. The optimization of working capital effectively and efficiently can have a major effect on achieving the maximum profit value for the contractor. Therefore, controlling cash flow is very important. One alternative that can be used to obtain maximum profit is the right scheduling. This study aims to plan scheduling optimally using the Ms.Poject ap`plication by utilizing float time. Where the utilization of float time uses a scheme with  25% down payment and without down payment. The float time variations used are 0%, 50% and 100%. An economic feasibility analysis was conducted to review the NPV, BCR, and ROI values. From the analysis results, the greatest profitability was obtained in the alternative without a down payment using 100% float. With an NPV value of Rp16,164,849,630, BCR value of 1.0651, and ROI value of 6.51%. It can be concluded that this alternative has maximum profitability.
Critical Discourse Analysis of Increasing Subsidized Fuel Price in 2022 by President Joko Widodo
Authors: Natasya Afrilia Ernes , Widodo Suko , Isnaini Santi
Published: September 2024

This research aims to uncover the meaning and ideology in the text of the speech as well as uncover the motives of certain interests related to President Joko Widodo's policy of increasing subsidized fuel prices. The method used is explanatory qualitative, the research object used is a transcript of the text of the speech on the increase in subsidized fuel prices on September 3 2022 by President Joko Widodo through triangulation. The results of the research show that in the text of the speech President Joko Widodo mentioned the word protect, but this diction was not in line with the data also conveyed in the text that the increase in subsidized fuel prices was caused by an increase in the APBN and inappropriate targets for subsidized fuel consumption enjoyed by the well-off. These two reasons for the increase in subsidized fuel prices actually illustrate the government's powerlessness in prioritizing the welfare of the people who should be prioritized in obtaining subsidized fuel.