bluuebunny/crossref_metadata_2025 huggingface dataset:
NARRATIVAS APRENDENTES EM UM CONTEXTO EM (TRANS)FORMAÇÃO
Authors: Martins José Lauro , Silva Bento Duarte da , Silva Valdirene Cássia da , Porto Junior Francisco Gilson Rebouças
Published: July 2017

A cibercultura e seus sistemas de comunicação imprimem uma nova amplitude à sociedade e exigem um novo modo de estudar, perceber e refletir sobre a força da comunicação e da educação, como processos de expressão da participação social, na contemporaneidade. Esse movimento legitima a pluralidade da comunicação e as transformações culturais, promovidas pelas tecnologias contemporâneas, que inauguram a essência social cotidiana: ensinar e aprender num território interativo, hipertextual e em rede, onde os sujeitos protagonizam transformações que determinam novos rumos a sociedade, em decorrência, sobretudo, da presença massiva das tecnologias digitais.
Assim sendo, os sujeitos postos nesse processo festejam o novo corpo social híbrido e diáfano que se faz e provocam metamorfoses nos mais diversos aspectos da vida humana, por meio de permutabilidades e deslocamentos constantes.  Assim, complexa e híbrida, a cultura contemporânea é decorrente do deslocamento de um mundo concebido em termos binários, no qual cada povo é um povo distinto de outro pela singularidade de seus traços culturais (BHABHA, 2001). Como consequências da pluralidade da comunicação e das transformações culturais, expandem-se as relações sociais, políticas, econômicas e culturais, e possibilitam novas formas de discursos, produção de significados e interações pessoais.
Nesse contexto, a informação e o conhecimento são projetados em uma dimensão horizontal de poder, quebra-se a dimensão hegemônica da informação por via de mão única, dando origem a novos atores - plurais, autônomos, anárquicos - e interações sociais mais livres, colaborativas e de caráter social perene. O contexto em questão é palco de novas relações e novas trocas de afetividades instantâneas que apresentam uma cultura ciber, marcada pela complexidade e pelo hibridismo, afetando o sujeito e seus vínculos sociais e culturais, nos processos instituídos pela comunicação, educação e tecnologias, possibilitando transformações: nos modos de ser e estar; nas interações e práticas sociais com os outros e na produção do conhecimento.
AVALIAÇÃO DA DIALOGIA EM FÓRUNS DE CURSO ONLINE: processo dialógico na formação de comunidades de sentidos
Authors: Martins José Lauro , Silva Valdirene Cassia da
Published: July 2017

Neste trabalho apresentamos os resultados parciais de uma pesquisa que procurou responder ao seguinte questionamento: os fóruns online têm sido por si mesmo um instrumento de aprendizagem ou mais uma burocracia com pouca eficiência pedagógica? Para isso analisamos a dialogia nos fóruns de estudos online de um curso de formação continuada de professores, numa abordagem quanti-qualitativa. Os resultados sinalizaram que os processos postos nos fóruns online se constituem uma coletânea de mensagens burocráticas sem as interações esperadas, comprometendo com isso a aprendência.
PLATAFORMAS EDUCOMUNICATIVAS ONLINE: o caso das rádios para crianças na Espanha e Portugal
Authors: Barbeito Veloso María Luz , Perona Páez Juan José
Published: July 2017

Este artículo explora la oferta sonora y los contenidos complementarios de las emisoras infantiles españolas y portuguesas que desarrollan su actividad en Internet. La investigación se adentra en el estudio de un fenómeno en expansión –sólo en España han visto la luz cuatro operadores de este tipo desde 2011- y evalúa hasta qué punto estas radiowebs se están convirtiendo en plataformas educomunicativas en línea. El análisis revela un marcado uso del podcast, al tiempo que evidencia cómo la música y la ficción –cuentos e historias breves- se erigen en los principales estandartes de unas redes alternativas a la oferta generalista.
MÍDIAS EDUCATIVAS “MAIS MULHERES”: um centro de documentação interdisciplinar de gênero e comunicação em Palmas, Tocantins, Brasil
Authors: Gonçalves Maia Marcos Felipe , Trindade Rocha José Damião , Meriqui Rodrigues Mariana
Published: July 2017

Aborda o projeto Mídias educativas mais mulheres do município de Palmas, Tocantins. Objetiva compreender a experiência da implantação de um Centro de Documentação sensível para as temáticas de gênero no cenário da Comunicação Social. Conclui destacando esse espaço como sendo de formação continuada, interdisciplinar e de atuação política.
A Concepção de Estado e a Administração Pública no Brasil no Âmbito do Plano Diretor de Reforma do Estado
Authors: Faria José Ricardo Vargas de , Faria José Henrique de
Published: July 2017

O presente ensaio teórico objetivou formular as bases para uma análise da chamada Reforma do Estado, incorporando também o estudo das transformações ocorridas no aparelho de Estado. Procurou-se evitar as opções tradicionalmente observadas na literatura administrativa que percebem as mudanças nas formas de administração pública como incorporações de técnicas das empresas privadas ou mesmo inovações surgidas da necessidade de resolver problemas de operação. Esta revisão pode tornar possível o questionamento dos objetivos anunciados pela Reforma do Estado no Brasil e a elucidação de outros não anunciados. O sentido das transformações pelas quais passa o Estado brasileiro passa pela análise das forças políticas (e suas alianças), seus projetos e ações. Observa-se que os períodos denominados de “modernização gerencial”, segundo o discurso oficial do Plano Diretor de Reforma do Estado, estão associados à abertura de novos campos e à flexibilização e melhoria das condições para aportes de capitais tanto nacionais quanto internacionais.
INFLUÊNCIA DA PODA DE FORMAÇÃO SOBRE O CICLO FENOLÓGICO DE PIMENTEIRAS EM VASO
Authors: Cruz Renata Ranielly Pedroza , Bezerra Ana Carolina , Travassos Amadeu Pimentel , Da Silva Eliane Nunes , Finger Fernando Luiz , Ribeiro Wellington Souto
Published: June 2017

Este estudo teve como objetivo determinar o efeito da poda de formação sobre o ciclo fenológico de dois genótipos de pimenteira para fins ornamentais: Pirâmide Ornamental (Capsicum frutescens) e Biquinho(Capsicum chinense). A primeira poda foi realizada quando as plantas apresentavam quatro a cinco pares de folhas verdadeiras. Os cortes foram realizados logo após o primeiro par de folhas apicais completamente expandidas. Quando as plantas iniciaram as brotações laterais e estas já estavam com mais de 5 cm, foi realizada a segundapoda, retirando o excesso de brotações laterais e mantendo apenas aquelas mais vigorosas de forma a se obter os seguintes tratamentos: plantas com duas hastes, plantas com três hastes e plantas sem poda (controle). Durante a condução do experimento, as pimenteiras foram avaliadas quanto à precocidade, caracterizada pelo tempo compreendido entre o plantio e a comercialização. A poda retardou em 15 e 10 dias a precocidade dos genótipos Biquinho e Pirâmide Ornamental, respectivamente. No entanto, a fase de frutificação e maturaçãonão foram alteradas, com exceção do genótipo Biquinho conduzido em duas hastes que retardou em 5 dias a fase de maturação.
Pensamiento crítico en los alumnos de la Universidad Nacional de Trujillo- 2014
Authors: Pando Tamara
Published: June 2017

La presente investigación se realizó con el propósito de determinar el desarrollo del pensamiento crítico a través de un programa de lectura comprensiva en los alumnos de la Universidad Nacional de Trujillo 2014 El estudio fue de tipo cuasi-experimental dentro de lo cual se tuvo el diseño pretest y postest con dos grupos, con una muestra de 72 alumnos, 30 hombres y 42 mujeres. Se procedió en primer lugar a la evaluación de los alumnos con el pretest en forma individual y con tiempo de 1 hora. A partir de entonces se procedió a aplicar el programa de lectura comprensiva de textos. Al finalizar la aplicación del programa se procedió a la aplicación del post-test. Se hicieron uso de los métodos cuantitativos, que se emplearon antes y después de la experiencia; y el método explicativo, para investigar acerca de las causas del porqué nuestro estudiante universitario no critica en los diversos espacios sociales del mundo que lo rodea. Los resultados obtenidos muestran que luego de aplicar el post-test al grupo experimental y control, se incrementaron significativamente los porcentajes en los niveles, literal, inferencial y crítico; por lo tanto existe una relación estadística positiva. Se concluye que la aplicación del programa de lectura comprensiva de textos desarrolla significativamente el pensamiento crítico en los alumnos, la cual debe ser reforzada desde el nivel educativo, con la finalidad de lograr competencias laborales y asegurar la empleabilidad de los estudiantes.Palabras claves: Programa de lectura comprensiva de textos, pensamiento crítico.DOI: http://dx.doi.org/10.21503/CienciayDesarrollo.2016.v19i2.09
Médiaműveltség az USA-ban – egy bostoni példa
Authors: Dóra László
Published: July 2017

Az Amerikai Egyesült Államokban is kiemelten fontos terület az iskolai oktatásban a médiaműveltség. A tengerentúlon az úgynevezett Thoman-modell az egyik leginkább elfogadott formája a médiaműveltség tanításának. Az amerikai iskolákban a modell javaslatai alapján a gyerekek gyakorlati feladatot is kapnak és ennek teljesítésén keresztül maguk is át tudják élni, hogyan működik a tömegkommunikáció a gyakorlatban. A médiaműveltségnek már számos leírása ismert Európában. Az Egyesült Államokban is hasonlóan gondolkoznak róla, és van egy régóta ismert modellje is, amelyet az oktatásban használnak. Egy bostoni szakközépiskolában gyakorlat közben is megﬁgyelhető, hogy a tengerentúlon mire helyezik a hangsúlyt a tömegkommunikáció értelmezése kapcsán.
Depersonalization of personal data and «big data» technology (bigdata)
Authors: Mavrinskaya Tatiana Vladimirovna , Loshkaroyv Andrey Viktorovich , Churakova Ekaterina Nikolavna
Published: June 2017

The question of the citizens' personal data processing is very important, and the solution for this problem should be the adoption of legislation expressly regulating the activities of personal data operators. The authors considered one of the most effective approaches to personal data protection – anonymization, as well as identified two developments to adoption of legislation. Anonymization not only protects the interests of the state and, first and foremost, the citizens, but it is also a mechanism that will allow advertising, insurance and other companies to improve the quality of their products and services.
Government regulation of gambling business
Authors: Stepasyuk Sergey Arkadyevich
Published: June 2017

The article deals with the problems of modern gambling business in the Russian Federation, political and legal, civil and economic aspects of state politics development in the field of activities regulation. The Federal Law regulating the activity of gambling business has been analyzed. The author has offered some developments of gambling business in the Russian Federation in order to increase the revenues to the budgets of the regions; to increase the attractiveness of the Russian resorts; to create more job opportunities and to eradicate unemployment.
Major economic problems of the company and possible ways to solve them
Authors: Semenov Aleksey Semenovich
Published: June 2017

This article describes major economic problems of the company and possible ways to solve them. Major economic problems of the company have been identified by economic analysis. The author has used Sabitskaya’s methodology to implement the analysis.
Management of transport system development (on thе ехаmрlе of Moscow city)
Authors: Kolgin Aleksandr Andreevich
Published: June 2017

This article describes the problem of the organization of transport system and measures taken by the government. These measures can help to create a rational system of transport in the city.
Beyond Efficiency: Value Frameworks for Public Administration
Authors: Rosenbloom David H.
Published: July 2017

Considering tradition and modernity in public administration encourages us to focus on the field's normative dimensions. Tradition teaches us that efficiency has not always been a dominant or default value for organizing public administration. Although efficiency rose to dominance in the 1930s, as with tradition, today it is contested by a plethora of competing public administrative values. Because there is no agreed upon framework for analyzing and organizing these values, this article offers a format for categorizing them and ordering their relationships to one another based on whether they are intrinsic, ancillary, or extrinsic to agency core missions.
A STUDY TO ASSESS THE LEVEL OF MENTAL HEALTH AMONG B.Sc NURSING FIRST YEAR STUDENTS IN SRM COLLEGE OF NURSING, KATTANKULATHUR.
Authors: S Dhanalakshmi , Mathiazhakan Ushapriya , M Hemamalini
Published: July 2017

Objectives: The present study aimed to determine the level of mental health adopted by 1st year B.Sc. nursing students.Methods: A total of 50 1st year B.Sc., nursing students were selected using non-probability convenient sampling technique. The tools used for data collection were William C. Menninger mental health assessment scale, and socio-demographic pro forma.Results: The studies revealed that 40 (80%) students have moderate mental health, 10 (20%) students have good mental health, and none of them have poor mental health. There is a significant association between the level of mental health among nursing students and with their demographic variable sex.Conclusion: The nurse administrator should plan and organize an educational program for nursing students, to prepare them to cope up with any stressful situations. Hence, the researcher emphasizes the need for more research to improve the level of mental health and by applying the research finding for future.
PICTOGRAM-BASED INFORMATION LEAFLET IN PATIENTS WITH PSORIASIS
Authors: Satheendran Swapna , Nagappa Anantha Naik , Pai Sathish
Published: July 2017

Objective: The objective of the study was to evaluate the impact of an information leaflet on the knowledge of disease in patients with psoriasis. Methods: A total of 50 patients with psoriasis on different treatment regimens were selected in the study. The pre- and post-test design (quasi-experimental design) was conducted for user testing of information leaflets (Baker Able design) which covered risk factors, signs and symptoms, and treatment options. The knowledge of psoriasis was assessed before and after the administration of the information leaflet and was compared using paired t-test. Results: At the follow-up interview, it was observed that patients were well informed about their skin disease but had less awareness about the risk factors and methods to cope with the disease. The overall user-testing knowledge assessment mean scores were observed to have significantly improved with p<0.001 after the introduction of the leaflet. Conclusion: The overall user opinion regarding the content of the leaflets was good. This study shows that an information leaflet given to patients with psoriasis can significantly improve their knowledge of the disease.
ISONIAZID THE CULPRIT BEHIND TOXIC OPTIC NEUROPATHY
Authors: Ommurugan Balaji , Bhattacharjee Dipanjan , Patil Navin
Published: July 2017

Literature regarding toxic optic neuropathy (TON) due to isoniazid (INH) is scarce. This diagnosis is often missed, leading to unnecessary delay in institution of corrective measures. Often, this delay can worsen the patient’s vision, with a high likelihood of development of serious damage to the patient’s vision. We report a case of a 49-year-old gentleman, afflicted with meningeal tuberculosis, who developed visual disturbances following the administration of antitubercular therapy. The patient’s vision improved dramatically following INH’s withdrawal. This case highlighted the need to keep INH as a possible cause for TON, especially if vision does not improve following ethambutol’s withdrawal. Further, this case attests to the need for thorough and periodic visual examinations in patients receiving antitubercular therapy.
SYNTHETIC ROUTES AND NATURAL SOURCES OF 2-PYRIDONE DERIVATIVES AND THEIR PHARMACOLOGICAL ACTIVITY
Authors: M Vijey Aanandhi , V Ravichandiran , Misra Prem Shankar
Published: July 2017

Objective: 2-pyridone is a well-known heterocyclic ring having significant biological and medical application. The molecular structures and various activities of 2-pyridone derivatives as well as their syntheses and natural occurrence are analyzed and reviewed, and their reactivity toward various nucleophiles is discussed.Methods: 2-pyridone derivatives, first naturally obtained and described as early as before the 19th century, have been attracting increasing attention in view of their high reactivity as building blocks for the preparation of compounds of various classes due to their selective transformations with different reagents. Much information describing the natural occurrence, synthesis and the significant biological activity of 2-pyridone compounds are scattered throughout the literature. There are short chapters dealing with the synthesis and activity of 2-pyridone derivatives.Results: After compiling the above material, the abundance of certain heterocyclic ring and nature of typical chemical transformations applied in current drug synthesis. It is likely this results from the abundance of these heterocycles in natural products such as alkaloids and various synthetic derivatives revealing different biological activity. This might suggest a classical approach to drug design where substrate analogs gain inspiration from existing natural ligands.Conclusions: The data considered in this review clearly demonstrate the high synthetic potential of 2-pyridone derivatives. Many biologically active heterocyclic compounds have been obtained based on this heterocyclic ring. This suggests that 2-pyridone can be used in the design of novel highly effective pharmaceuticals with a broad spectrum of bioresponses.
FORMULATION AND EVALUATION OF SELF-EMULSIFYING DRUG DELIVERY SYSTEM OF ETORICOXIB
Authors: Saurabh Surendra Singh , Issarani Roshan , Bp Nagori
Published: July 2017

Objective: In the present dissertation work, the aim was to prepare self-emulsifying drug delivery systems (SEDDS) of etoricoxib to improve its solubility with a view to enhance its oral bioavailability.Methods: The prepared SEDDS was the concentrate of drug, oil, surfactants, and cosurfactant. The formulation was evaluated for various tests such as solubility, globule size, thermodynamic stability study, pH determination, ease of dispersibility, uniformity index, drug content, in-vitro release study, and in-vitro permeation study.Results: The optimized formulation F6 showed drug release (79.21±2.73%), droplet size (0.546 μm). In vitro drug release of the F6 was highly significant (p<0.05) as compared to the plain drug.Conclusion: All formulations of etoricoxib SEDDS were showed faster dissolution than plain drug (p<0.05), mean bioavailability of etoricoxib increase in respect to the plain drug. The F6 can be further used for the preparation of various solid SEDDS formulations.
STUDY ON QUALITY OF LIFE ASSESSMENT IN DIABETIC RETINOPATHY AMONG PATIENTS WITH TYPE 2 DIABETES
Authors: Vijayan Meenu , Jose Rose , Jose Sruthy , Abraham Suja , Joy Jintu
Published: July 2017

Objective: The aim was to study the vision-related quality of life (QOL) for diabetic retinopathy (DR) among patients with Type 2 diabetes and to assess the direct medical cost of different treatment modalities. Methods: It was based on an individual-based analysis of QOL before and after the treatment for DR. The main objective of the study was to compare QOL between patients based on the different treatment modalities using vision function questionnaire (VFQ)-25, to evaluate the direct medical cost for DR patients undergoing different treatment modalities and to compare the cost and QOL of different treatment modalities in samples with non-proliferative DR (NPDR)/proliferative diabetic retinopathy (PDR) macular edema. The population included were patients with Type 2 diabetes with NPDR, with clinically significant macular edema and PDR, patients diagnosed to have diabetes above 5-year duration, adult patients, ocular pain those who are on regular follow-up and those who are willing to be a part of study. A total of 256 patients were selected out, of which 141 patients were satisfied the study criteria and participated in the study. Data relevant to the voice-related QOL study were obtained and recorded using VFQ-25 questionnaire. Other data relevant to the study were obtained and recorded in a semistructured data collection form by interviewing the patient or their caregivers and by direct examination of patient’s medical record. Expenditure was calculated in Indian Rupees. Results: After comparing the baseline QOL with QOL after treatment, it was found that the overall QOL of the study samples in accordance with the treatment undergone was found to be improved. The overall QOL had improved after the treatment for all samples and major improvement was seen on dependency, social functioning (SF), and mental health (MH). Conclusion: The overall QOL had improved after the treatment for all samples and major improvement were seen on dependency, SF, and MH. In conclusion, the study analyzed that intravitreal bevacizumab therapy is the cheapest one and with the comparatively same clinical outcome when compared with intravitreal ranibizumab therapy for macular edema cases in patients with NPDR and PDR.
ANTIDERMATOPHYTIC ACTIVITY OF STREPTOMYCES CACAOI SUBSP. CACAOI. M20
Authors: T Janaki
Published: July 2017

Objective: This study is an approach to find the alternative drug for the dermatophytosis because some of the existing antibiotics cause toxicity and also found expensive. Methods: There were 25 actinomycetes isolated from the soil sample of the mangrove, Avicennia marina from Ariyankuppam backwater area, Puducherry. Among the 25 isolates, the most active isolate, M20 was selected initially based on its antifungal activity, and it was checked for antidermatophytic activity against three dermatophytes, Microsporum gypseum, Trichophyton mentagrophytes, and Epidermophyton floccosum by agar plug method, well diffusion method followed by food poisoning technique. Release of volatile compounds from the isolate M20 has also been tested. Ultraviolet (UV)-vis spectral analysis of partially purified yellow compound fraction was done. Results: The isolate M20 actively controlled the growth of dermatophytes by agar plug method in the primary screening, well diffusion method in the secondary screening. The isolate was identified as Streptomyces cacaoi sub sp. cacaoi by 16sRNA sequencing analysis. The 10% (10 ml) culture filtrate of the isolate M20 was found to control the radial growth of these three dermatophytic fungi by food poisoning technique. Volatile compounds of the isolate M20 affected the mycelial growth of M. gypseum tremendously. Complete arrest of growth of M. gypseum was noticed with the combination of both volatile and non-volatile antibiotic compound of the isolate M20. The partially purified compound fraction (yellow) (0.5 mg/6 mm disc) inhibited the growth of M. gypseum (12 mm), and it was compared with the standard antibiotic clotrimazole (0.5 mg/6 mm disc), whose inhibition on M. gypseum was only 6 mm. UV-vis spectral analysis revealed the compound belonged to nucleoside antibiotics. Conclusion: It is evident that the mangrove actinomycetes are potential for preparing biomedicines for human welfare.
SYNTHESIS, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITIES OF ETHYL 2-(2-CYANO-3- (SUBSTITUTED PHENYL)ACRYLAMIDO)-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATES
Authors: K Madhavi , G Sree Ramya
Published: July 2017

Objective: Objective of the study was to synthesize and evaluate a series of novel compounds, ethyl 2-(2-cyano-3-(substituted phenyl)acrylamido)- 4,5-dimethylthiophene-3-carboxylates, for in vitro antioxidant and in vivo anti-inflammatory activities.Methods: Ethyl 2-(2-cyano-3-(substituted phenyl)acrylamido)-4,5-dimethylthiophene-3-carboxylates were synthesized by knoevenagel condensation of active methylene group of ethyl 2-(2-cyanoacetamido)-4,5-dimethylthiophene-3-carboxylate with substituted benzaldehydes. The synthesized compounds were evaluated for their in vitro antioxidant properties in three different models, viz., reduction of 1,1-diphenyl-2-pycrylhydrazyl free radical, scavenging of nitric oxide free radical, and ferric ion-induced lipid peroxidation using rat brain homogenate. Few selected compounds with good antioxidant properties were pharmacologically evaluated for anti-inflammatory activity by carrageenan-induced rat paw edema model.Results: Clean and efficient synthetic procedure was used for the preparation of series of compounds. The structures of synthesized compounds were confirmed by infrared, 1H nuclear magnetic resonance and mass spectra. The antioxidant activity data revealed that the compounds of ethyl 2-(2-cyano-3-(substituted phenyl)acrylamido)-4,5-dimethylthiophene-3-carboxylate containing phenolic substitution showed greater antioxidant activity. Hence, the active compounds were evaluated for anti-inflammatory activity and found to possess good activity. The percentage inhibition of rat paw edema obtained for the evaluated compounds was in the range of 70.2-83.1, comparable to the standard drug diclofenac (85.0%).Conclusion: The use of inexpensive, eco-friendly and readily available reagents, easy work-up and high purity of products makes the procedure a convenient and robust method for the synthesis of title compounds. The compounds of ethyl 2-(2-cyano-3-(substituted phenyl)acrylamido)-4,5- dimethylthiophene-3-carboxylate containing phenolic substitution showed greater antioxidant and anti-inflammatory activities.
POLYPHARMACY IN ELDERLY PATIENTS AND THEIR PROBLEMS
Authors: Fauziyah Siti , Radji Maksum , Andrajati Retnosari
Published: July 2017

Aging and diseases associated with aging is a condition associated with old age. An important approach to maintaining health status and physical examination in geriatric patients is very important, including nutrition problems, sight, hearing, urine containment, balance and fall prevention, osteoporosis, and polypharmacy. The use of polypharmacy will give some impact on the elderly, including increasing the improper treatment, adverse drug reactions (ADRs), and some of the problems that affect the changing nature of the pharmacokinetics and pharmacodynamics of drugs. Aging in the elderly with some diseases, the possibility of getting more number of drugs consequently has the potential to improve prescribing patterns that are not appropriate and contribute to ADRs and hospitalizations. This review will describe the effect of polypharmacy in elderly patients.
THE EFFECT OF TWEEN 80, PALM KERNEL OIL, AND ITS CONVERSION PRODUCT ON IN VITRO PENETRATION ENHANCEMENT OF INDOMETHACIN THROUGH RABBIT SKIN
Authors: Arianto Anayanti , Amelia Rizki , Bangun Hakim
Published: July 2017

Objective: Objective of the study was to evaluate the effect of Tween 80, palm kernel oil (PKO), and its conversion products (hydrolyzed and transesterificated products) on the in vitro rabbit skin penetration of indomethacin from hydrocarbon ointment base.Materials and Methods: In vitro penetration of indomethacin through hairless rabbit skin from hydrocarbon ointment base (white petrolatum) was evaluated using a diffusion cell. The effects of Tween 80, PKO, and its conversion products at various concentrations were evaluated.Results: The higher of the concentration of Tween 80 until 5%, the higher of the indomethacin penetration. However, at the concentration above 5%, the penetration was decreased with the increasing concentration of Tween 80 used. The amount of indomethacin penetrated increased with the increasing of the concentration of PKO and its conversion products used. Hydrolyzed product showed the higher indomethacin penetration enhancing effect than PKO. Transesterificated product showed the highest penetration enhancing effect. However, the combination of Tween 80 with transesterificated product showed lower penetration enhancing effect compared to transesterificated product only.Conclusion: Tween 80 at low concentrations, PKO, and its conversion products could be used to enhance indomethacin penetration.
EXTRACTION OF PHENOLIC COMPOUNDS AS ANTIOXIDANTS FROM SOME PLANTS AND THEIR CYTOTOXIC ACTIVITY AGAINST BREAST CANCER CELL LINE
Authors: Omran Rabab , Taee Zahraa Mal , Jassani Mohammed Jal , Hashim Hayder O
Published: July 2017

Objective: The objective of the study was to study the antioxidants and cytotoxic activities of phenolic extracts of some plants against breast cancer and normal cell lines.Methods: Phenolics were extracted from different parts of some plants (15) such as seeds, fruits, leaves, and rhizomes using methanol: ethanol: HCl: Distilled water at a ratio 50:29:1:20 (v:v:v:v). The contents of phenolics and flavonoids were estimated using gallic acid and quercetin as standards, respectively. The antioxidant activity was determined by 2,2ˋ-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging assay. Phenolic flavonoids were partially purified by adsorption chromatography using a silica gel column from selected plants and assayed their cytotoxic activity against breast cancer cell line Michigan Cancer Foundation-7 (MCF-7) and a normal cell line of non-tumorigenic fetal hepatic cell line (WRL-68).Results: The Cinnamomum zeylanicum extract had the highest phenolic and flavonoid contents were followed by Lawsonia inermis, Citrullus colocynthis, Syzygium aromaticum, Peganum nigrum, and Phoenix dactylifera. The antioxidant activity of Curcuma longa, P. dactylifera, C. colocynthis, Solanum melongena, and C. zeylanicum extracts had the highest ability to scavenge the free radicals. The acetone fraction of P. dactylifera and C. colocynthis extracts had the minimum inhibition dose that kills 50% of cells inhibitory concentration 50 values 156.91 μg and 1055.06 μg against MCF-7 and 372.86 μg and 153.8 μg against WRL-68, respectively. While the S. melongena extract had less effect on both cell lines.Conclusions: Phenolics as antioxidant substances had moderate or variable effectiveness on normal and cancer cell lines, and the highest concentrations were cancerous poison impact may be on normal cells over than cancer cells.
GAS CHROMATOGRAPHY 􀇧 MASS SPECTROMETRY ANALYSIS OF ESSENTIAL OIL COMPOSITION OF CLERODENDRUM SERRATUM L.: A TRADITIONAL PLANT OF INDIA
Authors: Tiwari Raj Kumar , M Udayabanu , Chanda Silpi
Published: July 2017

Objective: Clerodendrum serratum (L.) belonging to family Verbenaceae, commonly known as Bharangi, is a popular plant across various communities of India. Gas chromatography-mass spectrometry (GC-MS) is a unique technique to prospect various volatile principles and semivolatile compounds.Materials and Methods: The phytoconstituents present in the root of n-hexane extract were evaluated by GC-MS using Clarus 500 mass spectrometer.Results and Discussions: A total of 15 constituents were identified and characterized from the roots of C. serratum L. All the 15 compounds were tabulated with their retention time, percentage peak area, molecular formula, molecular weight, and Chemical Abstracts Service number. Out of all the compounds, 60% comprises the oxygenated compounds. Compound hexadecanoic acid, methyl ester, and benzene, 1,3-bis(1,1-dimethylethyl) showed highest percentage about 6.5 and 74.9, respectively.Conclusion: This study showed the presence of 15 compounds ranging from alkane, alkene as longest chain along with ester, aromatic and nonaromatic hydrocarbons.
CLOPIDROGEL INDUCED LEUKOCYTOCLASTIC VASCULITIS
Authors: Patil Navin , O Balaji , Rao Karthik , A Talha , Chaitan Chaitan
Published: July 2017

Cutaneous adverse drug reactions are very common in a hospital setting while treating patients. Drug-induced vasculitis is a very common form of vasculitis affecting all age groups, and many drugs have been implicated in causing vasculitis. Clopidogrel is an antiplatelet drug used in the management as well as prevention of coronary artery disease. It is known to cause various side effects ranging from bleeding, gastrointestinal disturbances, to skin rashes. Leukocytoclastic vasculitis is a form of hypersensitivity vasculitis and is very rarely seen with clopidogrel. Hence, we report a case of clopidogrel-induced leukocytoclastic vasculitis in an old male patient after coronary stenting.
STUDY THE POTENTIAL ANTIOXIDANT EFFECT OF VITAMIN D3 SUPPLEMENTATION ON THE LEVEL OF EXTRACELLULAR SUPEROXIDE DISMUTASE IN ASTHMATIC PATIENTS
Authors: Abbas Rasha Saadi , Abdulridha Manal Khalid , Shafek Mostafa Abdalfatah
Published: July 2017

Objective: This study was designed to evaluate the potential antioxidant effect of vitamin D3 supplementation in chronic asthma patients.Methods: A total of 44 candidate patients were diagnosed with asthma allocated as Group 1 includes 20 patients assigned to receive conventional therapy for asthma and Group 2 includes 24 patients assigned to receive conventional therapy for asthma plus 2000 IU vitamin D3 tablet for 3-month period. Furthermore, 30 apparently healthy subjects were included in the study as a control group. Pulmonary function test, serum 25-hydroxy vitamin D levels, serum extracellular superoxide dismutase (SOD3) levels were measured before and after 3 months therapy.Results: The mean forced expiratory volume in 1 second (FEV1) both the measured and the percentage of predicted value showed a highly significant increase after 3 months treatment compared to pre-treatment value in both study groups (p<0.01). When compared to pre-treatment value, there was no significant increase in forced expiratory volume in one second to forced vital capacity ratio (FEV1/FVC) in Group 1 (p>0.05), nevertheless, Group 2 showed highly significant increase after 3 months (p<0.01). Approximately, 90-96% of adult asthmatic patients revealed vitamin D deficiency (<20 ng/ml). Post-treatment with adjuvant vitamin D3 therapy, 25% of patients obtained acceptable level of vitamin D sufficiency (≥30 ng/ml). After 3 months of the treatment, Group 1 patients showed a significant decrease in mean SOD3 level compared to pre-treatment level (p<0.05), while Group 2 patients showed a significant increase in mean SOD3 level compared to pre-treatment level (p<0.05).Conclusion: Most of the asthmatic patients revealed vitamin D deficiency and supplementation with vitamin D3 reduce oxidative stress burden in those patients.
Habitar la ciudad
Authors: Mansur Garda Juan Carlos
Published: July 2017

Recibido: 14/10/2015 • Aceptado: 02/02/2017

En este texto se busca ahondar en la noción del habitar para comprender qué es habitar la ciudad. A lo largo de este artículo se advierte que más allá de ocupar un espacio, habitar es vivirlo de forma creativa, simbólica y libre, y señala como elementos fundamentales del habitar el «cuidado», el «amparo», el «arraigo» y el «encuentro». Estos elementos permiten comprender que habitar es un ethos  y las ciudades son la manifestación de nuestra forma de expresar nuestros deseos e intereses por nosotros mismos, por los demás y por las cosas que nos rodean, por esto, se habita la ciudad cuando se hace ciudadanía, y se encarnan nuestras relaciones sociopolíticas y económicas, que se reflejan en las formas arquitectónicas y urbanas de las ciudades.
Spectral Efficiency Analysis of GSM Networks in South-South Nigeria
Authors: Elechi Promise , Alalibo T. A.
Published: July 2017

In this paper, the technique of multiplicity was used to analyse GSM network capacity in Nigeria. An evaluation of Enhanced stochastic knapsack was used as an approach for resource sharing in multiservice by adopting the Erlang Loss Model in analyzing the SMS capacity. The offered traffic that is Lost Traffic based was used to dimension the system resources. To actualize this work, measurements were conducted in Benin City and Port Harcourt to determine the best signal characterization of the southern part of Nigeria. Based on the measurement data, a model was developed to predict the traffic intensity of the region. Comparisons were carried out on the different types of frequency hopping and the variant DFH based power was applied in improving the spectral efficiency of the network. The results showed that the spectral efficiency increased, as the number of cell per cluster decreased. The optimal value of the number of cell in the cluster caused reduced interference, since the reduced interference could allow the users to achieve higher rates.
Condenser Heat Recovery For Combined Cooling-Heating and Power Generation using Isentropic Fluid
Authors: Dubey Kaushalendra Kumar , Mishra R. S.
Published: July 2017

The thermodynamic study of combined cooling, heating and power generation system with the recovery of heat source from the condenser of 1MW thermal power plant. The R-134a working fluid based Organic Rankine Cycle (ORC) is introduced in the proposed thermodynamic analysis and the provision of parabolic trough collector is recommended for solar heating purpose. The analysis of the system shows thermal efficiency and multiple effects like Heating- Cooling and Power through heat recovery of thermal power plant. This analysis also express the resulting process heat obtained and the cooling effect of solar integrated as well as non-solar integrated system. The results conclude that the thermal efficiency as well as heating-power and cooling effects increases by 30-40% in the case of solar integrated as compare to without solar system.
Using Electric Current as a Weed Control Method
Authors: Sahin Hasan , Yalınkılıc Mehmet
Published: July 2017

Weed struggle has an important place in agricultural production. The widespread use of chemicals in this struggle is due to its easy applicability, its short-term results, and its economic efficiency. However, the negative effects of these chemicals on the environment and human health have been recognized, and the interest in non-chemical struggle methods has also increased. One of the non-chemical methods of struggle is using electric energy. In this work, which is carried out by passing the electric current through the plant, it is aimed that ended the vital activity of weed (cress), as a result of electric current flowing through it. The experimental setup prepared for use in operation consists of a voltage regulator with 1-300 V steps and copper conductors which will contact the plants. In the experiments, weed seeds germinated under suitable conditions were placed on the board to complete the electric circuit and the circuit was completed by passing current through the plants that the copper conductor tips contacted. As a result of the experiments, plants were observed to lose their vitality about 70% when 100 volts of electricity was applied over the body for 300, 420 and 540 seconds. On the other hand, when electric energy was applied as 200 volts and 300 volts for 300, 420, and 540 seconds, respectively, the vital activity of the plants close to 100% was ended.
Neuro-Fuzzy Approach to Forecast Wind Power in Portugal
Authors: H.M.I. Pousinho  , V.M.F. Mendes  , J.P.S. Catalão
Published: July 2017

The increased integration of wind power into the electric grid, as nowadays occurs in Portugal, poses new challenges due to its intermittency and volatility. Hence, good forecasting tools play a key role in tackling these challenges. In this paper, a neuro-fuzzy approach is proposed for short-term wind power forecasting in Portugal. Results from a real-world case study are presented. A thorough comparison is carried out, taking into account the results obtained with other approaches. Conclusions are duly drawn.
Performance Evaluation of Microgrid Management Function in KERI pilot plant
Authors: Jong-Yul Kim  , Jin-Hong Jeon  , Seul-Ki Kim
Published: July 2017

As  usual,  the  microgrid  operates  in  grid-connect mode,  but,  when  a  fault  occurs  in  the  upstream  grid,  it  should disconnect  and  shift  into  islanded  operation  mode.  In  grid-connect  mode,  the  controlling  power  flow  at  PCC  is  necessary management  function  rather  than  the  frequency  and  voltage. However, the controlling the frequency and voltage is asked in islanded    mode.    To    achieve    these    management    goals appropriately,    the    cooperative    control    strategy    among microsources  is  needed.  This  supervisory  control  action  is executed   at   MMS.   In   this   paper,   the   cooperative   control strategy   of   microgrid   components   is   presented   and   the management performance is evaluated by using microgrid pilot plant.  The  pilot  plant  consists  of  the  PV,  PV/Wind  Hybrid system,  BESS,  diesel  generators,  and  RLC  loads,  which  are connected to 380V low voltage lines. The test results show that the  proper  control  strategy  can  ensure  stability  of  microgrid  in islanded  mode  and  maintain  the  power  flow  of  PCC  at  desired value successfully.
Energy saving in road tunnels by means of transparent tension structures
Authors: A. Peña García  , L.M. Gil-Martín  , A. Espín Estrella  , F. Aznar Dols
Published: July 2017

The high and constant rate of energy
consumption in road tunnels has led researchers to look for
more and more efficient lamps and luminaries. The solutions
developed have partially contributed to energy saving but
consumption is still high, specially in the threshold zone which
requires very high levels of luminance, and the solutions found
still have important contras like colour performance. In this
work, we present a completely different solution: the extension
of the “threshold zone” out of the tunnel by means of a
transparent tension structure to let visible solar radiation go into
the tunnel and achieve the required levels of luminance during
daytime without any kind of electrical lighting.
Risk Assessment for Cloud Computing
Authors: Sivasubramanian Yogeshwaran , Ahmed Syed Zubair , Mishra Ved Prakash
Published: July 2017

Abstract—The broad implementation of cloud computing has brought a dramatic change to multiple industries, which derives from the development of the Internet-related technologies. Cloud service providers have untangled a lot of issues to maintain a robust quality of service. Despite the utilization of proficient techniques in resource management that has made optimal planning possible, as one resource is allocated to multiple users the risk of resources unavailability in cloud computing is still present. The level of risk is evaluated based on the probability of an incident occurring, which is mapped against the estimated negative impact. The probability of an incident occurring can be determined by the threat exploiting the vulnerability. All though a zero-risk scenario is impractical, effective risk assessment strategies equipped with efficient mitigation mechanisms can decrease the negative impact. As of now there are three types of cloud computing systems public, private and hybrid each with different levels of security. Most In this paper, we examine the various risk assessment models with regards to a Cloud Computing and touching upon Information Assets and Risk, Privacy and Confidentiality Concerns, Data Governance.

 IndexTerms—Cloud Computing,Risk Assessment,Risk Impact. Risk Management
Cloudlet Networks Performance Analysis and Improvement
Authors: Hassan Jameela Abdulla , Al-Dosari Fahad
Published: July 2017

Abstract— Cloud computing is a Participation in the process and storage operations across distant servers that are shared by many organizations and users and thus be transferred from an application to a service. The organization can share data over the Internet and user can pay only for the resources that will be used only. While cloud computing has disadvantages, there are some advantages for cloudlets have over cloud computing which include: lower network latency and users having full ownership of the data shared. When the need of data to be stored in the servers grows quickly, the workload in every resource will grow too. So, we need a load balancing algorithm and the load balancing is important issue in the cloud environment. Load balancing defined as a technique that divides the extra load equally across all the resources to ensure that no one resource overloaded. . So the performance of the cloud can be improved by having an excellent load balancing strategy. For that we will discuss the existing load balancing algorithms in cloud computing and propose algorithm to improve round robin algorithm by CloudAnalyst simulator  based on a factor of  response time and processing time  and the proposed algorithm was found to be best in response time and processing time when we compare it with round robin algorithms.

 

Index Terms— Cloud Computing, CloudAnalyst, Load Balance, Mobile Cloud Computing, Cloudlet Networks.
Tội phạm tình dục tại Đồng Nai qua giám định y pháp trong 3 năm từ 2010 đến 2012
Authors: Luu Hung Sy , Tran Hoang Van , Nguyen Anh Tuan , Trinh Ha Xuan
Published: June 2017

Tội phạm tình dục hiện đang tăng nhanh gây ảnh hưởng sâu sắc đến sức khỏe của nạn nhân. Nghiên cứu được thực hiện tại trung tâm Pháp Y Đồng Nai trong thời gian từ 01/01/2010 đến 30/10/2012, chúng tôi thu thập được 354 nạn nhân. Số nạn nhân ở lứa tuổi dưới 15 là 63,1%; từ 16 - 25 là 33,3%; hiếm gặp trên 36 tuổi. Trong đó 4,8 % số nạn nhân đến khám ngay sau khi bị nạn; trong 12h là 18,6%; sau 24h là 15,1% và 13% nạn nhân đến khám sau 1 tháng. Số nạn nhân bị thương tích ở các vị trí ngoài vùng sinh dục chiếm 4,9%; chủ yếu gặp xây sát da tay, chân. Rách màng trinh chiếm tỷ lệ 66,9% bao gồm rách cũ và mới; tụ máu màng trinh chiếm 13,8%. Có 33,1% số nạn nhân không rách màng trinh.
Nota editorial
Authors: Bautista Álvaro
Published: June 2017

Nota Editorial
How Do We Meet the Challenge of Whiplash?
Authors: Elliott James M. , Walton David M.
Published: July 2017

A previous special issue of JOSPT (October 2016) discussed whiplash in terms of the clinical problems and current research surrounding prevention, biomechanics of injury, emergent care, imaging advancements, recovery pathways and prognosis, pathogenesis of posttrauma pain, acute and chronic management, and new predictive clinical tools. While great strides have been made in the field of whiplash and are continuing in earnest, a key group of clinicians and academics have recognized that inconsistent outcomes in published literature hamper our ability to meaningfully synthesize research findings, leading to results of systematic reviews that provide very few concrete clinical recommendations. We are optimistic that improved outcomes for people with whiplash-associated disorder (WAD) are attainable in the near future, as interdisciplinary research efforts continue to align internationally, new mechanisms are identified and explored, and advanced statistical techniques allow complex questions to be answered in clinically meaningful ways.

J Orthop Sports Phys Ther 2017;47(7):444–446. doi:10.2519/jospt.2017.0106