bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Pemasaran Tabungan Junior di PT. Bank Syariah Indonesia KCP Medan Marelan
Authors: Perdana Siregar Anri Akta , Atika Atika
Published: September 2024

Junior savings service is currently one of the service the best provided by the bank to support bank operasional activities become more effective and efficient. The goal is to facilitate the performance of a product bank service, so as to increase customers based on the number of customers of Bank syariah indonesian users of Junior savings reached around 50% responding to this, Bank Syariah indonesian seeks to improve and mainttain the quality of service provided to attract customers. The problem in this research what is the Bankâ€™s strategy that is an obstacle to improving the quality of Junior savings service. The purpose of this research is to find out the strategy of Bank Syariah indonesian in improving service quality and to find out what are the obstacles for Bank Syariah indonesian in improving the quality of junior savings services and to find out what are the solutions for Bank Syariah indonesian in facing obstacles to improve the quality junior savings services. Banking. The method used in this research is a field study, this method is used to find out how far the suitability between the theories used is with the actual situation of the object under study. In this field study using interviews and observation. And the type of research used is descriptive qualitative research as a whole it can be concluded from this research is the strategy of Bank Syariah Indonesian in improving service quality, namely launching "New junior savings Bank Syariah indonesian".
Analisis Pengaruh Utang Luar Negeri Dan Pengeluaran Pemerintah Terhadap Pertumbuhan Ekonomi Indonesia
Authors: Humairah Zaskya
Published: September 2024

This study was conducted to determine and analyze the effect of external debt and government spending on economic growth, in this case GDP. The sample used is time series data from the period 1985-2014 on foreign debt, government spending and GDP ( Gross Domestic Product) taken from World Bank data. The sample in this study berjumalh 30 data that will be used as the object of research. The dependent variable in this study is economic growth using data on Indonesia'S GDP, while the independent variable is the external debt and expenditure of the Government of Indonesia. To see the effect of independent variables and dependent variables, researchers perform multiple linear regression analysis test also perform classical assumption test. Based on the research results obtained, it can be seen that simultaneously foreign debt and government spending have a significant effect on Indonesia's economic growth. Furthermore, partially, foreign debt has a positive and significant effect on economic growth, and government spending also has a positive and significant effect on Indonesia's economic growth.Â Â
Pengaruh Kecakapan Pribadi Dan Kecakapan Sosial Terhadap Keberhasilan Usaha Di Pusat Perbelanjaan Pasar Petisah Medan
Authors: Rachmahlija Selfia , Lestari Nasution Annio Indah , Aslami Nuri
Published: September 2024

The existence of small and Medium Enterprises (SMEs) in developing countries can be said to be the backbone of a country's economy. The success of small and medium enterprises (SMEs) has proven to be able to move the wheels of the nation's economy and reduce the number of unemployed in the country. In this study, researchers see the phenomenon that personal skills and social skills in business actors in the Petisah market is very minimal. In addition, there are also some efforts that look forward and crowded and some vice versa. This study aims to determine how the influence of personal skills and social skills on the success of businesses in the shopping center petisah medan market with respondents totaling 91 businesses selected through a simple random sampling technique. This study is an associative quantitative research. The variables of this study are personal skills and social skills and business success which consists of 7 dimensions, namely capital increase, production, number of customers, business expansion, expansion of marketing areas, improvement of physical facilities and business income. The research Data were analyzed using multiple linear regression analysis techniques and the results showed R^2 = 0.602 ; F = 66.521p_1= 0.573 p_2 = 0.932 the skills of business actors contributed 60.2% to the success of the business, personal skills and social skills have a positive and significant effect on business success. The results of this study are expected to provide an understanding of self-regulation and good communication skills and affect the success of the business so that business actors and prospective business actors can further develop it for the sake of a successful business undertaken.
Konversi Buku Ajar Pendidikan Agama Islam ( PAI) SMP Menjadi Modul Berbasis Contextual Learning
Authors: Nihaya Wajihan , Nurzannah Nurzannah
Published: September 2024

One of the integral parts of the national curriculum is religious learning. In Indonesia itself, the subject of Islamic Religious Education is required to be studied by students from elementary, middle, high school, to tertiary level, both in formal and non-formal schools, especially in schools that In fact, this madrasah research uses a qualitative descriptive method, which is a research method that utilizes qualitative data and is described descriptively. Research related to the conversion of Islamic Religious Education textbooks has produced a product in the form of a learning module for class 7 at junior high school level which specifically focuses on odd semester material and consists of 5 chapters. The process of converting textbooks into modules requires several stages to reach the finishing process.
Penggunaan Media Grafis Dalam Pembelajaran Fiqih Untuk Mempermudah Pemahaman Siswa Kelas 9 di MTsN Karo
Authors: Tarigan Iga Mawarni Br , Kasduri Mario
Published: September 2024

In the learning process, teachers must use the right materials and media, because they are an important part of the process of learning that can facilitate student understanding, one of the learning media that can help students understand is the graphic media. The study aims to find out how the use of graphic media in Fiqih learning to facilitate the understanding of 9th grade students at MTsN Karo. The type of research conducted by researchers is a type of qualitative research with a descriptive qualitative approach. The data obtained in the form of photographs, documentation and interviews. The results of the study are research on the use of graphic media in Fiqih learning at MTsN Karo has found that it is effective in facilitating the learning of students of Class 9. The use of graphic media by teachers and students is crucial because it can significantly improve the learning process. Teacher and student motivation in using the graphic medium is also important, because it helps them understand the material better and engage with the teacher's explanation. The study also found that the use of the graphical media increases student interest and involvement, making it a significant and beneficial factor in learning. The study concludes that graphic media can be a useful tool in teaching Fiqih.
Pengaruh Online Marketing, Simpati, Dan Inovasi Brand Terhadap Keputusan Pembelian di Warung ATK Purnima
Authors: Hendry Raja Saul Marto
Published: September 2024

The ATK industry is one of the fastest growing sectors, including one of the emerging stores in Rantauprapat, Warung ATK Purnima. Warung ATK Purnima is present as one of the major players in providing various ATK products. In an increasingly competitive context, factors such as online marketing, sympathy, and brand innovation play a crucial role in shaping consumer purchasing decisions. ATK industry is a sector that continues to grow and has an important role in meeting the aesthetic and personal care needs of the community. Demand for ATK products continues to increase along with increased consumer awareness of the appearance and health of the skin. By providing a variety of quality ATK products, this store has managed to attract the attention of consumers and build a positive image. Warung ATK Purnima is famous for its emphasis on product innovation. Through careful research and development, the store is always introducing new and high-quality products, in line with the latest ATK trends. By creating a comfortable, friendly and interactive shopping environment, the store has managed to build good relationships with customers, create loyalty and support the growth of its business.
Analisis Perbandingan Kinerja Keuangan Sebelum Dan Sesudah Spin-Off Dengan Metode RGEC Studi Kasus BCA Syariah di Indonesia
Authors: Syawaluddin Rizalul Muslih , Nurlaila Nurlaila , Hasibuan Nur Fadhilah Ahmad
Published: September 2024

This research aims to compare the financial performance of Bank BCA Syariah before and after the spin-off. This type of research is quantitative research with the data source used is secondary data. This research uses BCA Syariah bank annual financial report data for 2008-2021. The research sample is Bank BCA Syariah 2008-2021. Data processing and analysis techniques using Descriptive Statistical Analysis, Normality Test and Hypothesis Testing using Paired Sample T-Test and Wilcoxon Signed Rank Test. The program used for calculations uses SPSS version 25 and then the results from SPSS are interpreted. The research results show that there is a comparison of financial performance seen from the NPF, FDR, GCG, ROA and ROE variables before and after the spin-off at BCA Syariah 2008-2021.
Analisis Strategi Pemasaran Dalam Meningkatkan Jumlah Kepesertaan Bukan Penerima Upah (BPU) Studi Kasus BPJS Ketenagakerjaan Cabang Padangsidempuan
Authors: Harahap Sovia , Nawawi Zuhrinal M. , Inayah Nurul
Published: September 2024

Membership of Non-Wage Recipients in BPJS Ketenagakerjaan at the Padangsidempuan Branch office has decreased in 2019. Many branch offices have not been able to achieve the participation target, especially Non-Wage Recipient membership. The lack of knowledge of these self-employed workers regarding BPJS Employment considers that BPJS Employment is only for formal workers only those who work with agencies or companies and interactions and information related to membership of non-wage earners are limited, making it difficult for workers. The type of research used by researchers is field research using a qualitative approach. Data collection techniques used by researchers are interviews and observation. The results of this study are that Employment BPJS implements a marketing strategy that is able to change employment conditions by taking advantage of existing opportunities and minimizing threats from outside the company. The strategies used are extensification, intensification, and retensification strategies. And other efforts made by Employment BPJS to expand membership are taken through the private sector in providing protection for workers. Conduct intensive educational and outreach activities to business actors and workers to increase awareness. Regarding improving the quality of services, BPJS Employment has optimized the simplification and standardization of claims processes and services that are safe and very easy through the JMO (Jamsostek Mobile) application, and Bukalapak Asik (service without physical contact), as well as increasing engagement and retention with participants.
Profil Gaya Belajar Ditinjau Dari Tipe Kepribadian Disc
Authors: Sihai Non , Romiaty Romiaty , Feronika Nopi , Sukarningsi Susi
Published: September 2024

Gaya belajar merupakan pola pikir khusus individu dalam menerima, mengolah informasi dan mempelajari keterampilan baru. Tujuan dari penelitian ini adalah untuk mengetahui gambaran gaya belajar ditinjau dari tipe kepribadian DISC. Metodologi penelitian menggunakan penelitian survei dan menganalisisnya. Hasil dari penelitian menunjukkan bahwa: (1) Tipe Kepribadian Dominance memiliki gaya belajar Visual sebanyak 8%, Auditory 5% dan Kinestetik 10%; (2) Tipe Kepribadian Influence memiliki gaya belajar Visual sebanyak 5%, Auditory 5% dan Kinestetik 8%; (3) Tipe Kepribadian Steadiness memiliki gaya belajar Visual sebanyak 24%, Auditory 3% dan Kinestetik 21%; (4) Tipe Kepribadian Compliance memiliki gaya belajar Visual sebanyak 3%, Auditory 0% dan Kinestetik 8%. Kesimpulannya adalah mahasiswa program studi Bimbingan dan Konseling memiliki tipe kepribadian Steadiness sebanyak 17 orang dari 38 responden dengan  gaya belajar visual dan kinestetik. Artinya bahwa mereka memiliki tipe kepribadian yang sangat menyukai proses, mau tekun berusaha, loyalitas dan mampu bekerja sama secara tim. Mereka lebih mudah untuk mempelajari materi secara visual dan praktek langsung.
Incremental Content of Accounting Information when Local Options of IFRS are Applied: Empirical Evidence from an Emerging Economy
Authors: Boonyanet Wachira , Promsen Waewdao
Published: September 2024

This study aims to assess the incremental useful information provided by accounting data when Thai listed companies were temporarily exempted from certain TFRS standards due to the COVID-19 pandemic. The analysis covers 2,504 observations of the companies listed on the Stock Exchange Thailand from 2018 to 2021, spanning two years before and after the pandemic. The study uses market-based performance including Tobin’s Q, book value per share, market value per share, and price per book as proxies to gauge the information value. Descriptive statistics and multiple regression are used to analyze the data, and the study employs IQR and Boxcox techniques to validate the data. The overall results suggest that accounting information provides incremental value on market-based performance both pre and post-the-temporary exemption from TFRS. Earnings per share emerged as the most significant factor influencing market-based performance, followed by cash flows of investing activities, both before and after the relief. Market value per share was perceived by investors as the most crucial measure of incremental information from accounting data, followed by book value per share. Companies that paid dividends showed a significant relationship with all firm values post the relief period. Finally, fair value accounting is one of the vital topics being scrutinized when there are signs of economic turmoil. These findings are particularly beneficial for stock markets in emerging economies.
Review of Research and Key Recommendations for the Safe Use of Oral Anticancer Drugs
Authors: Агафонова Юлия Андреевна , Снеговой Антон Владимирович , Омельяновский Виталий Владимирович , Вахрушева Татьяна Сергеевна , Гребенникова Ольга Петровна , Сельчук Владимир Юрьевич
Published: September 2024

Введение. Международным профессиональным сообществом созданы специализированные программы менеджмента, рекомендации и инструкции, разработанные для медицинских работников и пациентов, принимающих пероральные формы противоопухолевых лекарственных препаратов (ПОЛП). Однако в русскоязычном сегменте исследований и научной литературы имеется ограниченное количество фрагментарных данных по безопасной практике применения пероральных ПОЛП.
Цель. Обозначить ключевые аспекты безопасности терапии пероральными ПОЛП, а также привести перечень рекомендаций по безопасному применению, предназначенных для использования как пациентами, так и медицинскими работниками. Авторы рекомендуют к использованию структурированные рекомендации The MASCC Oral Agent Teaching Tool (MOATT) ассоциации Multinational Association of Supportive Care in Cancer (MASCC) и адаптированные для самостоятельного применения пациентом рекомендации «Oral Chemotherapy Education» ассоциации The National Community Oncology Dispensing Association (NCODA). Авторами данной статьи осуществлен перевод и адаптация рекомендаций MASCC, которые доступны на официальном сайте ассоциации на русском языке для практического применения и проведения дальнейших исследований.
Prognostic Multifactorial System Predicting Risk of Metastasis in Uveal Melanoma
Authors: Яровая Вера Андреевна , Левашов Илья Андреевич , Яровой Андрей Александрович
Published: September 2024

Введение. Прогнозирование течения увеальной меланомы (УМ) подразумевает анализ клинических, морфологических и генетических особенностей опухоли — многочисленных и разнородных по своей природе факторов. Отсутствие единого прогностического подхода затрудняет стратификацию рисков метастазирования УМ как в клинической практике, так и при информировании пациента о прогнозе заболевания, что обуславливает актуальность в разработке собственного прогностической системы.
Цель. Разработка комплексной системы индивидуального прогнозирования риска метастазирования УМ с учетом клинических, морфологических и молекулярно-генетических факторов.
Материалы и методы. Всего были отобраны данные 202 пациентов c УМ. В качестве первичного метода лечения в 57 % случаев проводилась энуклеация (n = 115), в 43 % случаях (n = 83) — лучевая терапия. При органосохраняющем лечении материал для цитологического и молекулярно-генетического исследования был получен с помощью тонкоигольной аспирационной биопсии (ТИАБ). Оценивались ключевые клинические (размер и локализация опухоли, пол и возраст), морфологические (клеточный тип и инвазия в цилиарное тело) и молекулярно-генетические (мутации в генах EIF1AX, SF3B1, PPARG, MYC) факторы.
Результаты. Средний срок наблюдения составил 42 мес. (медиана 35, min 1, max 182). В данный период было отмечено 78 случаев метастазирования (39 %). Были определены факторы, статистически значимо (p < 0,01) влияющие на риск метастазирования УМ: размер, локализация и клеточный тип опухоли, мутации в генах EIF1AX, PPARG, MYC.
Выводы. Разработанная комплексная система прогнозирования риска метастазирования увеальной меланомы, учитывающая эти факторы, позволила стратифицировать риск метастазирования по баллам и выделить три достоверно различающихся между собой (p < 0,01) категории прогноза: «неблагоприятный», «средний» и «благоприятный». Система требует валидации на данных других пациентов с УМ.
Mimicry in Oncology: A Rare Clinical Case of Inflammatory Pseudotumor of the Liver
Authors: Бусько Екатерина Александровна , Козубова Ксения Вячеславовна , Кулиш Анна Васильевна , Багненко Сергей Сергеевич , Любимская Эльвира Сергеевна , Климашевский Валерий Фёдорович
Published: September 2024

Воспалительная псевдоопухоль печени — редкое поражение с неспецифическими клиническими и лучевыми признаками. Данное заболевание представляет интерес в связи с отсутствием патогномоничной лучевой картины, вследствие этого имитацией злокачественного поражения и возможными ошибками в дифференциальной диагностике. Нами представлено клиническое наблюдение мужчины 47 лет со спонтанным регрессом воспалительной псевдоопухоли печени. Целью клинического наблюдения являлась демонстрация мультимодальной визуализации рассматриваемого заболевания. Несмотря на редкую встречаемость и широкий полиморфизм, врачам различных специальностей следует знать о данной патологии и включать в дифференциально-диагностический ряд при постановке диагноза и выборе тактики дальнейшего ведения пациента.
The Potential of Sentinel Lymph Node Biopsy Using the Fluorescent ICG Method in the Staging and Treatment of Skin Melanoma
Authors: Титов Константин Сергеевич , Джамилов Шерали Раджабалиевич , Лебединский Иван Николаевич , Сорокина Маргарита Викторовна , Гурьева Полина Михайловна , Греков Дмитрий Николаевич
Published: September 2024

Введение. Своевременные диагностика и эффективное лечение меланомы кожи являются весьма актуальными, поскольку имеется неуклонный рост ее заболеваемости, а также смертность от данной злокачественной опухоли существенно превышает значения, зафиксированные при других онкологических заболеваниях кожи. Биопсия сигнального лимфатического узла (БСЛУ), как уточняющая диагностика, может приводить к индивидуализации прогноза заболевания и к изменению стадии опухолевого процесса с назначением эффективной адъювантной таргетной или иммунотерапии, которые повышают вероятность полного излечения данных пациентов.
Материалы и методы. В настоящей статье проанализированы данные выполнения БСЛУ флуоресцентным методом с ICG при локализованной меланоме кожи в клинической практике ГБУЗ ММНКЦ им. С.П. Боткина ДЗМ. Проанализированы данные о 54 пациентов с локальными стадиями меланомы кожи туловища и конечностей (Ib-IIС ст., ЕСOG 0-1), которым была проведена операция: иссечение опухоли кожи с БСЛУ флуоресцентным методом с применением индоцианина зеленого (ICG). В дальнейшим оценивалось течение послеоперационного периода и проводились контрольные обследования через 3 и 6 мес., с целью исключения локо-регионарных рецидивов.
Результаты. По данным срочного патоморфологического исследования, микрометастазы выявлены у 3 (6 %) пациентов, а по данным же планового ИГХ исследования, метастатическими оказались лимфатические узлы (ЛУ) у 8 (15 %) пациентов. Отсутствие микро- и макрометастатического поражения ЛУ (рN0) у 43 (79 %) пациентов. Ни у одного из пациентов послеоперационных осложнений не наблюдалось, аллергических реакций также не выявлено. При контрольных обследованиях у группы с отсутствием поражения ЛУ (pN0) признаков локо-регионарного рецидива выявлено не было. Три пациента с выявленным прогрессированием при контрольных обследованиях были из группы с позитивными сигнальными лимфатическими узлами (СЛУ).
Выводы. По данным оценки нашего опыта, флуоресцентная методика с применением индоцианина зеленого (ICG) для детекции СЛУ при локальной меланоме кожи туловища и конечностей безопасна и высоко эффективна. Данная методика позволяет точно, а главное своевременно, стадировать меланому кожи и подбирать оптимальную и персонализированную тактику дальнейшего лечения и наблюдения.
PAPEL DO ENFERMEIRO OBSTÉTRA NO CUIDAR DA MULHER NO CLIMATÉRIO
Authors: Neves Gabriela , Vilares Sara , Galhanas Ana , Frias Ana
Published: September 2024

O organismo feminino, quando entra no climatério, sofre mudanças físicas em diversos órgãos e tecidos decorrentes do declínio hormonal provocado pela disfunção ovárica. A qualidade de vida durante o climatério relaciona-se diretamente com a durabilidade, frequência e intensidade das manifestações físicas, influenciando a vida emocional da mulher. É uma altura marcada por adaptações e reajustes de estilos e hábitos de vida, sendo difícil para algumas mulheres aceitar e reconhecer a nova realidade pessoal. Um ambiente compreensivo e respeitador para com a mulher é importante para que esta consiga aceitar as mudanças físicas, adquira autoestima e seja capaz de desassociar esta fase como um declínio do seu valor enquanto mulher. Enquanto profissionais de saúde, a assistência à mulher no climatério implica prestar apoio neste percurso de aceitação e adaptação, capacitando-a através da transmissão de informação, com o objetivo de ajudar a mesma a compreender as mudanças do seu organismo e a preservar e melhorar a sua qualidade de vida. O Enfermeiro desempenha um papel fundamental no apoio à mulher no climatério, que engloba educação para a saúde, o suporte emocional e a promoção de saúde, com o objetivo de proporcionar à mulher uma melhor qualidade de vida durante esta transição.
Capacity Building Sebagai Upaya Pemberdayaan Kapasitas Ekonomi Lokal di KWT Sekar Asri
Authors: Purwandari Heru , Fadilah Umi Nurul , Zefanya Michelle Lola , Kinanti Lu’lu’ Hiswari , Samudra Samudra , Purwandari Heru , Furoida Dian Ashfi
Published: September 2024

Pembangunan pertanian harus melibatkan seluruh lapisan masyarakat, termasuk perempuan. Perempuan dapat melakukan banyak hal jika mereka diorganisir dan dilatih dengan baik. Salah satu program pemerintah untuk mensejahterakan petani adalah program Kelompok Wanita Tani (KWT). Aksi pengembangan masyarakat dilakukan di KWT Sekar Asri yang terletak di Desa Ciherang, Kecamatan Dramaga, Kabupaten Bogor. Pengembangan ini dilaksanakan pada bulan Februari hingga Mei 2024. Tujuan dari kegiatan ini yaitu mengidentifikasi potensi dan permasalahan, aktor yang terlibat, jaringan mitra serta merancang upaya pengembangan (kapasitas, jaringan, komunikasi, informasi, dan edukasi dengan pelibatan teknologi). Metode yang digunakan pada program ini yaitu penyampaian materi dan demonstrasi langsung. Program ini terdiri dari kunjungan perkenalan dengan mitra dan mengidentifikasi masalah yang dihadapi mitra, penyusunan program berdasarkan masalah bersama mitra, pelatihan pembukuan dan pengenalan sosial media sebagai media pemasaran, penentuan packaging bersama mitra, serta pelatihan pembuatan konten.
Desestabilização de pacientes psiquiátricos com bipolaridade em fase maníaca no mês de agosto: uma revisão bibliográfica
Authors: Azevedo Luiza Moura de Souza , Silva Uanderson Pereira da , Silveira Francis Moreira da
Published: September 2024

Introdução: O transtorno bipolar é uma condição psiquiátrica com episódios alternantes de mania e depressão. Na fase maníaca, os pacientes apresentam euforia intensa, hiperatividade, comportamento impulsivo e redução do sono, o que torna a gestão clínica desafiadora. O mês de agosto, que representa o fim do inverno e o início da primavera no Hemisfério Sul, pode ser crítico, devido às transições climáticas e ambientais que impactam a estabilidade emocional dos indivíduos. Objetivo: Analisar a possível correlação entre a desestabilização de pacientes com transtorno bipolar, durante a fase maníaca, e o mês de agosto. Método: Foi realizada uma pesquisa qualitativa, do tipo revisão de literatura. A busca das fontes foi feita nas bases de dados: Scientific Electronic Library Online (Scielo); Biblioteca Virtual em Saúde (BVS), Pubmed, Scopus e PsycINFO, envolvendo o período de 2014 a 2024. Resultados: As mudanças sazonais influenciam o humor e os ciclos de sono, que são fatores críticos na regulação do humor em pacientes com transtorno bipolar. O mês de agosto, em muitos lugares, é marcado por alta exposição solar, o que pode desencadear ou exacerbar episódios maníacos. Conclusões: A quebra de rotina, viagens ou eventos sociais intensos podem ser estressores que desestabilizam pacientes em fase maníaca.
Recent Advances in Orthodontics
Authors: Vaibhav T D , Hameed Faizee K.M. Shahul , Jyosthna A. , Dhayananth L. Xavier , Ranganathan Sukanya
Published: September 2024

This review highlights the progress in orthodontics. Advances in the field have enhanced diagnostic efficiency and streamlined treatment planning. Modern technologies such as computer applications, electronic dental models, artificial intelligence, and cephalometric applications give orthodontists a significant advantage over traditional diagnostic methods. The stereolithography technique offers valuable diagnostic insights, predicts surgical outcomes, and assists in creating surgical guides. CAD/CAM technology enables the milling of virtual arch forms and lingual retainers, reducing chair time. Laser innovations improve the efficiency of etching, bonding, and even accelerate orthodontic tooth movement. Additionally, developments in brackets and archwires have made significant strides. Ultimately, it is up to the clinician to utilize these advancements wisely to achieve optimal aesthetic results for patients.
Cigány bűnelkövetők vagy „cigánybűnözés”?
Authors: Tóth Csaba
Published: September 2024

The author explores the professional and political interpretations of the term which connects ethnicity with criminality.
Ahol nem fúj a változás szele
Authors: Vucseta Zoltán
Published: September 2024

The author comments on the career-patterns of the Hungarian police force.
A Reflection of Community Dilemmas Driven by the Advent of Coronavirus in Eclectic Rural Contexts in South Africa
Authors: Sithole-Tetani Ntombophelo , Qotoyi Andile , Kang’ethe Simon Murote
Published: September 2024

In the 2020-2021 epoch, South Africa faced the arduous challenge of fighting COVID-19 due to limited resources. This paper reflects how the disease affected communities in eclectic rural contexts in South Africa. This article applied a review of the literature methodology. The researchers drew their literature from journal articles, book chapters, and informal community conversations amid the researchers’ experiential intuition. The article reflects that South African rural communities faced coronavirus-driven dilemmas due to the following factors: Society being subjected to conflicting messages, a state of stigma and stigmatisation, misleading information packaging, fear associated with failure to understand the disease’s aetiology and epidemiology; and states of poverty associated with loss of several business closures and termination of employment; the phenomenon of myths and misinformation; scepticisms and conspiracies; as well as a manifestation of various forms of love deficit. This article recommends that social service professionals such as psychologists, counsellors, and social workers be on the frontline to conduct psychotherapeutic education to communities to build their resilience to fight the coronavirus. The study provides scientific data on the historical glimpse of the impact of pandemics in rural communities of South Africa. It prepares societies for other pandemics that may come in the future.

Keywords: Community Dilemmas, Coronavirus, Myths, Entrepreneurial Spirit, Fear.
Generative tools of AI in education
Authors: Mironova Julija , Riiascshenko Viktoria , Bondarenko Andrey , Kinderis Remigijus , Verdenhofa Olga
Published: September 2024

Since generative tools of Artificial Intelligence appeared in education, ongoing discussion arose. Still, higher education institutions argue if generative tools can be used, and if yes, what exactly can be accepted. The purpose of this study is to investigate for what exactly students use the generative tool Chat GPT in their studies, as well as to determine if there is a statistically significant difference between students representing different fields of study in terms of usage of Chat GPT in general, as well as in evaluation of the knowledge. The objectives of the study are to research recent scientific findings, as well as to analyze the results of the survey created by authors, which was distributed in Latvia, Lithuania, Ukraine, Bulgaria and Uzbekistan. Methods of the study are analysis of the recent findings and statistical analysis of the survey. To test hypotheses, the authors employed the Kruscal-Wallis non-parametric test for both hypotheses, where authors tested if there are statistically significant differences between answers of students from different education fields. The final results highlight the use of Chat GPT by students in higher education.
Comment on “Excluding Primordial Black Holes as Dark Matter Based on Solar System Ephemeris”
Authors: Cline James M.
Published: September 2024

It was recently claimed (https://arxiv.org/pdf/2408.10799) that solar system ephemeris data can exclude primordial black hole (PBH) dark matter in the mass range 1018–1022 g. I show that this conclusion is based on an implausible, implicit assumption; namely the uncertainty on the solar system mass within 50 au is as small as the uncertainty on the mass of the Sun. Correcting for this error, I find that ephemeris data can only constrain PBH’s with mass below 1016 g, which is already excluded by constraints on their evaporation via Hawking radiation. Correcting a further error concerning the time-averaged rate of such fluctuations nullifies even this weaker constraint.
Well-balanced Hydrodynamics for the Piecewise Parabolic Method with Characteristic Tracing
Authors: Zingale Michael
Published: September 2024

Well-balanced reconstruction techniques have been developed for stellar hydrodynamics to address the challenges of maintaining hydrostatic equilibrium during evolution. I show how to adapt a simple well-balanced method to the piecewise parabolic method for hydrodynamics. A python implementation of the method is provided.
Determination of the Abundance of Mercury from the Hg ii Line at 5677.10 Å in Late B-type Stars. VI. HD 173524 (46 Dra)
Authors: Monier Richard
Published: September 2024

The weak line of Hg ii located at 5677.10 Å is used to measure the mercury abundance in the most massive component of the SB2 HgMn star HD 173524 (46 Dra). This line is detected at 3σ above the noise in the adjacent continuum. The synthesis of this line, confirms a large overabundance of mercury, about +5.00 dex, which is less than the excess derived from the 3983.93 Å line in earlier studies. Spectrum synthesis yields estimates of the abundance deficiencies/excesses for sixteen other elements. Helium, carbon, oxygen, magnesium, silicon, chromium and iron are depleted. Phosphorus, titanium, manganese, gallium, strontium, yttrium, zirconium and barium are overabundant. Platinum is very overabundant. For several elements, these new abundances differ from earlier measurements.
The Effect of Foreign Portfolio Investments on Istanbul Stock Exchange BIST-30 Analysis
Authors: Orta Kenan
Published: September 2024

This chapter presents the findings of a study which aimed to investigate the effect of foreign portfolio investments in companies traded in the BIST-30 index after the 2008 crisis on the market value, stock closing price and stock return of companies. Another aim of this study was to examine the effects of macroeconomic variables such as real effective exchange rate, CPI index and current account deficit. For these purposes, daily stock changes, market value and foreign share data of Borsa İstanbul BIST-30 companies for the years 2010-2014 were collected. In the study, six different models were tested. Although the findings of the research differ from model to model, they provide information about the general tendencies of foreigners. The findings shed light on the effects of portfolio investments on the market value of companies for investors and researchers.
Analyzing the Impact of Information Features on User Continuance Intent in Recommendation Systems
Authors: Li Weikai
Published: September 2024

Under the protection of recent legislation, users are increasingly opting to disable personalized recommendation features in applications. This study, for the first time from an information perspective, draws on Psychological Reactance Theory and Innovation Resistance Theory to explore the impact of the semantic characteristics of personalized recommendation information on users' intentions to continue using the application. A contextual analysis based on the intensity of social media use is conducted. Empirical evidence is derived from cross-sectional data of Chinese users. The results indicate that information characteristics affect users' perceived freedom risks and threats, inhibiting their intention to continue using the application. The intensity of social media use moderates this inhibition. As one of the earliest studies to explore discontinuing personalized recommendations, the research deepens the understanding of how recommendation systems affect users' behaviors. It provides feasible insights for developers to optimize recommendation systems.
Investigation and Modelling of Barriers in Adoption of Blockchain Technology for Accounting and Finance
Authors: Chavali Kavita , V. V. Ajith Kumar , Mavuri Sudha , Tiwari Chandan Kumar , Pal Abhinav
Published: September 2024

Blockchain technology has attracted considerable attention from both academicians and industry players in different industries, such as accounting and finance, because of its transformative potential of re-engineering the process of operation and enhancing the level of required transparency in these industries. However, despite the various possibilities of transforming the accounting and finance sectors, there are still numerous challenges that hinder the further development of blockchain technology in the domain. The various obstacles to the adoption of blockchain in accounting and finance are interconnected and include a diverse set of issues related to technology, organization, regulations, and knowledge. To overcome these obstacles, it is necessary to take a comprehensive approach that includes improving technical proficiency, encouraging cooperation among stakeholders, negotiating intricate regulations, and cultivating a culture of innovation and adaptation within enterprises.
Efficacy of Psidium guajava (L.) Leaves Extract Against Spodoptera frugiperda J.E. Smith (Lepidoptera: Noctuidae) Larvae
Authors: Soomro D. M. , Ahmed A. M. , Khoso F. N. , Kubar M. I. , Ali A. , Abbasi F.
Published: September 2024

Purpose: Fall armyworm (FAW) Spodoptera frugiperda J.E Smith is an invasive pest of maize crops that has been recently reported in Pakistan (2019). Synthetic insecticides are the main choice of local farmers to control this deadly pest, but with continuous use of these pesticides health and environmental issues have arisen, which demands an alternative control measure. Considering this pest’s significance, this study was conducted to determine the potentiality of Guava (Psidium guajava L.) against the third instar larvae of S. frugiperda; which is considered an effective repellent effect.Research Method: The P. guajava leaves were extracted with methanol, ethyl acetate, n-hexane, and chloroform; each extract was prepared at different concentrations of 125, 250, 500, and 1000 ppm. Later, the larval mortality was recorded at different intervals of 24, 48, 72, and 96 hrs, and antifeedant activity at 24 hrs.Findings: The highest mortality of 92.86% was observed on methanol extract at 1000ppm after 96 hrs. The mortality on all crude extracts and at every concentration increased at different intervals of the observation and reached the maximum at 96 hrs. However, the LC50 and LC90 values of 154.77 and 865.3ppm after 96 hrs were recorded in methanol. Similarly, the highest antifeedant activity was 87.5% recorded in methanol at 1000ppm, and the lowest antifeedant activity of 22.58% was noted in chloroform extracts at 125ppm concentration. It showed that the antifeedant activity relied on a concentrated dose; meanwhile, the P. guajava with methanol crude extracts successfully stopped the feeding activity of S. frugiperda.Originality/ Value: Therefore, based on the obtained results, the P. guajava leaf extracts are highly recommended, particularly for their extraction with methanol and n-hexane which showed the highest larval mortality and antifeedant activity of S. frugiperda.
Effect of Processing Millets on the Glycemic Index Variability and Development of Digital-ready Reckoner for Consumers
Authors: Azeez T. B. , Keerthana G. Amuthu , Aswini M. , Kiruthigha V. , Subhalakshmi S. U.
Published: September 2024

Purpose: Millets, as nutri-cereals, offer potential health benefits aiding in the prevention of metabolic disorders like diabetes, obesity, CVD etc. Recognizing their significance, the UN has designated 2023 as the International Year of Millets to enhance global awareness and consumption. To validate their efficacy for individuals with metabolic disorders, the question arises: “Are millets good for individuals suffering from metabolic disorders.”Research Method: Millets were purchased from the markets of the Dindigul and Theni districts. This study examines the morphological characteristics, nutrient, phytonutrient composition, and In vitro glycemic index of Finger millet and Kodo millet in unpolished (UP), semi-polished (SP), and polished (P) forms. Furthermore, the study involved standardizing eight dishes using UP millets, calculated their nutrient content and estimated the dietary fibre and In vitro glycemic index. A digital-ready reckoner was developed based on these findings.Findings: The results indicated that the nutrient, phytonutrient composition and In vitro glycemic index were promising in the unpolished Finger and Kodo millet. The estimated GI values of the millet dishes ranged from 29±0.09 to 39±0.17. Standardized dishes made from unpolished ragi and varagu fall under the low glycemic index according to the GI classification.Research Limitations: The result revealed that ratooning of rice can be possible in non-saline soil where available water is present otherwise it’s not possible in high-saline soil as well as water deficit areas.Practical Value: The Developed ready reckoner will be of use to the public to create awareness of the differential processing of millets and to understand that the degree of polishing is of utmost importance; otherwise, the bitter truth is millets are also obesogenic.
Ebi3 Binding to IFN-γ and IL-10 Limits Their Function
Authors: Scott Ellen N , Ye Cheng , Yano Hiroshi , Lipatova Zhanna , Brunazzi Erin , Vignali Kate M , Workman Creg J , Vignali Dario A A
Published: September 2024

EBV-induced gene 3 (Ebi3) is a β subunit within the IL-12 cytokine family that canonically binds to α subunits p19, p28, or p35 to form the heterodimeric cytokines IL-39, IL-27, and IL-35, respectively. In the last decade, the binding partners for Ebi3 have continued to expand to include IL-6 and the other IL-12 family β subunit p40, revealing the possibility that Ebi3 may be able to bind to other cytokines and have distinct functions. We first explored this possibility utilizing an in vivo mouse model of regulatory T cell–restricted deletions of the subunits composing the cytokine IL-35, p35, and Ebi3, and we observed a differential impact on CD8+ T cell inhibitory receptor expression despite comparable reduction in tumor growth. We then screened the ability of Ebi3 to bind to different cytokines with varying structural resemblance to the IL-12 family α subunits. These in vitro screens revealed extracellular binding of Ebi3 to both IFN-γ and IL-10. Ebi3 bound to IFN-γ and IL-10 abrogated signal transduction and downstream functions of both cytokines. Lastly, we validated that extracellular complex formation after mixing native proteins resulted in loss of function. These data suggest that secreted partnerless Ebi3 may bind to cytokines within the extracellular microenvironment and act as a cytokine sink, further expanding the potential immunological impact of Ebi3.
Structure of a Human Monoclonal Antibody in Complex with Outer Surface Protein C of the Lyme Disease Spirochete, Borreliella burgdorferi
Authors: Rudolph Michael J , Chen Yang , Vorauer Clint , Vance David J , Piazza Carol Lyn , Willsey Graham G , McCarthy Kathleen , Muriuki Beatrice , Cavacini Lisa A , Guttman Miklos , Mantis Nicholas J
Published: September 2024

Lyme disease is a tick-borne, multisystem infection caused by the spirochete Borreliella burgdorferi. Although Abs have been implicated in the resolution of Lyme disease, the specific B cell epitopes targeted during human infections remain largely unknown. In this study, we characterized and defined the structural epitope of a patient-derived bactericidal monoclonal IgG (B11) against outer surface protein C (OspC), a homodimeric lipoprotein necessary for B. burgdorferi tick-mediated transmission and early-stage colonization of vertebrate hosts. High-resolution epitope mapping was accomplished through hydrogen deuterium exchange–mass spectrometry and X-ray crystallography. Structural analysis of B11 Fab-OspCA complexes revealed the B11 Fabs associated in a 1:1 stoichiometry with the lateral faces of OspCA homodimers such that the Abs are essentially positioned perpendicular to the spirochete’s outer surface. B11’s primary contacts reside within the membrane-proximal regions of α-helices 1 and 6 and adjacent loops 5 and 6 in one OspCA monomer. In addition, B11 spans the OspCA dimer interface, engaging opposing α-helix 1′, α-helix 2′, and loop 2–3′ in the second OspCA monomer. The B11-OspCA structure is reminiscent of the recently solved mouse transmission blocking monoclonal IgG B5 in complex with OspCA, indicating a mode of engagement with OspC that is conserved across species. In conclusion, we provide a detailed insight into the interaction between a functional human Ab and an immunodominant Lyme disease Ag long considered an important vaccine candidate.
TLR7-Induced Mitochondrial Reactive Oxygen Species Production in Monocyte-derived Dendritic Cells Drives IL-12–Dependent NK Cell Activation and Enhances Antitumor Immunity
Authors: Paladhi Ankush , Daripa Samrat , Nath Arghya , Hira Sumit Kumar
Published: September 2024

Dendritic cell (DC)–based vaccines are promising immunotherapies for cancer. Although DC-based therapies are known to activate tumor-specific T cells, the interplay between DCs and NK cells in this setting is not fully understood. In this study, we demonstrated a novel TLR7/ mitochondrial reactive oxygen species (mROS)/IL-12 axis that drives potent NK cell responses against tumors. We showed that TLR7 activation by imiquimod in peripheral blood monocyte-derived CD11c+ DCs triggered mROS production, leading to enhanced IL-12 secretion and subsequent NK cell activation, as evidenced by increased IFN-γ production and tumor cell cytotoxicity. Notably, mROS neutralization abrogates NK cell–mediated tumor cell lysis, and TLR7-mediated DC activation of NK cells occurs independently of MyD88, suggesting involvement of the noncanonical NF-κB pathway. Our findings provide a rationale for targeting the TLR7/mROS/IL-12 axis to enhance the efficacy of DC-based cancer immunotherapy.
Reconciling the pain with gain of Church leadership conflict in Zimbabwe
Authors: Tagwirei Kimion
Published: September 2024

Since time immemorial, there has been demonisation of conflict that entangles Church leaders and congregants in Zimbabwe. Innumerable publications have exposed multifarious negative effects of ecclesial conflicts, such as dividing the parties involved, splitting churches and creating space for dubious and cultist opportunists to take up leadership positions at the expense of gullible believers. While this happens, focusing on the negative consequences of conflict prolongs the hurt and pain, while delaying healing, closure, peace and development. Thus, the positive effects of conflict represent a critical gap in need of attention. Employing qualitative literature review, biblical peace and conflict management principles, this submission reconciles the aforementioned downsides with the upsides of Church conflict, such as necessitating introspection and exposing hidden issues that need attention. It finds conflict unavoidable, yet sometimes destructive, constructive and indicative that certain issues must be addressed. All in all, it recommends that Church leaders should not delay, or rub off, but manage conflict and upgrade their conflict management as well as peace building skills in view of biblical precepts to stay progressive in any situation.Contribution: This article reconciles the negative with the positive effects of Church leadership conflicts to achieve ecclesial and community development.