bluuebunny/crossref_metadata_2025 huggingface dataset:
Bisphosphonates for the prevention of osteoporotic fractures in postmenopausal women with osteopenia: a systematic review and meta-analysis
Authors: Yureneva S. V. , Averkova V. G.
Published: August 2024

BACKGROUND: The lack of sufficient systematization of data on the use of bisphosphonates for primary prevention of osteoporotic fractures in postmenopausal women with osteopenia prompted us to conduct a systematic review with meta-analysis of publications devoted to this problem.AIM: To study the effect of bisphosphonates on bone mineral density (BMD), markers of bone metabolism and fractures in postmenopausal women with osteopenia.

   MATERIALS AND METHODS: A total of 1140 potentially eligible articles were found in the initial publication screening. From the initially identified results, 13 studies were meta-analyzed. The design of the studies selected for meta-analysis was consistent with randomized controlled trials.

   RESULTS: On average, study bisphosphonate preparations compared with placebo increased lumbar spine BMD by 5.54 % (95 % CI 4.44–6.63, I2 = 93.65 %), total hip BMD by 4.53 % (95 % CI 3. 2–5.86, I2=96.32 %), femoral neck BMD by 3.63 % (95 % CI 1.5–5.75, I2=95.9 %), total body BMD by 3.25 % (95 % CI 2.28–4.22, I2=87.87 %), proximal femur BMD by 4.76 % (95 % CI 3.43–6.08, I2 = 88.64 %). There was a statistically significant effect of bisphosphonates on low-energy fractures (OR 0.62; 95 % CI 0.49–0.77), clinical vertebral fractures (OR 0.51; 95 % CI 0.38–0.69), and radiologically confirmed vertebral fractures (OR 0.63; 95 % CI 0.4–0.98).

   CONCLUSION: These results obtained allow us to conclude that bisphosphonates (alendronate, zolendronic acid, ibandronate, resedronate) have a positive therapeutic effect, and their administration is justified in postmenopausal women with osteopenia for the prevention of osteoporotic fractures and increase in BMD.
Features of the course of complicated injury of the lower cervical spine depending on the timing of surgical decompression of the spinal cord
Authors: Statsenko I. A. , Lebedeva M. N. , Palmash A. V. , Lukinov V. L. , Rerikh V. V.
Published: August 2024

Objective. To determine the influence of the urgency of performing surgical decompression of the spinal cord (SC) on the course of acute and early periods of complicated injury of the lower cervical spine.Material and Methods. The results of treatment of 75 patients with acute complicated injury of the lower cervical spine with ASIA A and ASIA B severity of spinal cord injuries were retrospectively analyzed. Two groups were formed, depending on the timing of surgical decompression of the spinal cord after injury. Group I included 33 patients in whom the SC decompression was performed within the first eight hours after the injury, and Group II included 42 patients in whom the SC decompression was performed in more than eight hoursafter the injury.Results. The mean age of patients in Group I was 29 [25; 39] years, in Group II – 35 [30; 42] years (p = 0.129). There were 31 (94.0 %) male patients in Group I and 38 (90.5 %; p > 0.999) in Group II. The time from the moment of injury to decompression of the spinal cordwas 6.1 [5.0; 7.5] hours in Group I and 16.9 [11.8; 39.6] hours in Group II (p < 0.001). Pneumonia developed in 55 % [38 %; 70 %] of patients in Group I and in 86 % [72 %; 93 %] of patients in Group II (p = 0.004). The duration of pneumonia in Group I was 18 [8; 20] days, and in Group II – 28 [20; 39] days (p < 0.001). It was shown that the risk ratio for developing pneumonia in patients with delayed decompression of the spinal cord was 2.08 [1.17; 3.67] times higher (p = 0.01). The duration of mechanical ventilation in Group I was 12 [7; 17] days versus 19 [11; 26] days in Group II (p = 0.001). Maintaining the target blood pressure levels ≥ 85 mm Hg was required in 73 (97.3 %) patients with a duration of hemodynamic support of 6 [3; 10] days in Group I versus 10 [5; 15] days in Group II (p = 0.019). It was shown that SC decompression within the first eight hours after injury reduced the proportion of patients with a SOFA score of 4 points or more by 20 % in the acute period and by 42 % by the fifth day of the early period of injury. Positive dynamic in neurologicalstatus was recorded in 30.0 % [17.0 %; 47.0 %] of patients in Group I and only in 2.0 % [0.0 %; 12.0 %] of patients in Group II (p < 0.001). The duration of treatment in the ICU was 20 [16; 25] days in Group I and 29 [23.5; 41.75] days in Group II (p = 0.001).The total length of hospital stay was 38 [27; 46] days in Group I versus 57 [45.75; 67.50] days in Group II (p < 0.001). Mortality was recordedonly in Group II and amounted to 5.3 %.Conclusion. Decompression and stabilization surgery within the first eight hours after the injury, together with a complex of intensive care measures for acute complicated injury of the lower cervical spine have a significant positive effect on the course of the acute and early periods of traumatic SC disease.
Conserving Sidi Affane mosque: heritage, building archaeology, and historical challenges
Authors: Koreichi Choubeila , Debache-Benzagouta Samira
Published: August 2024

Heritage preservation requires a personalized approach, with a specific date for each element. For historic buildings, especially religious sites, knowing their history, is crucial to maintain authenticity and guide conservation decisions: complex materials and construction techniques, as well as changes over time, make this task essential. Most of the renovation projects in Constantine since 2014, following its designation as the Arab capital of culture, were carried out after the preparatory works, leaving many mosques closed, including the mosque Sidi Affane. A methodology, derived from building archaeology integrates archaeology and architecture and aims to unveil the mosque's mysteries, offering a holistic understanding of its history through interdisciplinary collaboration. Our analysis of Sidi Affane mosque seeks to establish an archaeological-architectural analysis method based on meticulous elevation readings. This approach not only holds scientific significance but also serves a practical purpose by contributing to the preliminary study for the mosque's restoration and enhancement.
On 𝐿𝑝 boundedness of rough Fourier integral operators
Authors: Wu Guoning , Yang Jie
Published: August 2024

In this paper, we deal with the

L
p

L^{p}

boundedness of rough Fourier integral operators

T

a
,
φ

T_{a,\varphi}

with amplitude

a
⁢

(
x
,
ξ
)

∈

L
∞

⁢

S
ρ
m

a(x,\xi)\in L^{\infty}S_{\rho}^{m}

and phase function

φ
⁢

(
x
,
ξ
)

∈

L
∞

⁢

Φ
2

\varphi(x,\xi)\in{L^{\infty}}{\Phi^{2}}

which satisfies a measure condition.
We show that

T

a
,
φ

T_{a,\varphi}

is bounded on

L
p

L^{p}

for

1
≤
p
≤
∞

1\leq p\leq\infty

if

m
<

n
⁢

(

ρ
−
1

)

p

−

ρ
⁢

(

n
−
1

)

2
⁢
p

m<\frac{n(\rho-1)}{p}-\frac{\rho(n-1)}{2p}

when

1
≤
p
≤
2

1\leq p\leq 2

or

m
<

n
⁢

(

ρ
−
1

)

2

−

ρ
⁢

(

n
−
1

)

2

⁢

(

1
−

1
p

)

m<\frac{n(\rho-1)}{2}-\frac{\rho(n-1)}{2}(1-\frac{1}{p})

when

2
≤
p
≤
∞

2\leq p\leq\infty

.
Our main results extend and improve some known results about

L
p

L^{p}

boundedness of Fourier integral operators.
On the singular directions of a holomorphic mapping in P
n(ℂ)
Authors: Wu Nan
Published: August 2024

In this paper, we investigate the existence of singular directions, singular radii and indirect singular points of holomorphic curves
in

P
n

⁢

(
ℂ
)

{P^{n}(\mathbb{C})}

.
α-, β- and γ-duals of the sequence spaces formed by a regular matrix of Tetranacci numbers
Authors: Khan Izhar Ali , Meitei Mayanglambam Udoy
Published: August 2024

The primary objective of this paper is to create a novel infinite Toeplitz matrix by leveraging Tetranacci numbers. This matrix serves as the foundation for defining new sequence spaces denoted asc0⁢(G){c_{0}(G)},c⁢(G){c(G)},ℓ∞⁢(G){\ell_{\infty}(G)}, andℓp⁢(G){\ell_{p}(G)}, where1≤p<∞{1\leq p<\infty}. By utilizing this newly constructed matrix, the paper also explores and examines various algebraic and topological properties inherent to the sequence spacesc0⁢(G){c_{0}(G)},c⁢(G){c(G)},ℓ∞⁢(G){\ell_{\infty}(G)}, andℓp⁢(G){\ell_{p}(G)}for values ofpwithin the range of1≤p<∞{1\leq p<\infty}. At last, we also prove existence theorem with example for infinite systems of differential equations inℓp⁢(G){\ell_{p}(G)}.
Increase in the frequency of melanism in Abert’s Squirrel in Boulder, Colorado
Authors: Barrett Lake H. , Nunes Christian A. , Lehtinen Richard M.
Published: August 2024

In the northern portions of its range, Abert’s Squirrel (Sciurus aberti) has two color morphs: a wild-type gray morph and a melanistic morph. Using camera traps, citizen science data and in-person observations in and near Boulder, Colorado (USA), we compared current color morph frequencies to those reported in a 1969–1971 study. At all study sites, we observed a large and statistically significant increase in the frequency of the melanistic morph compared to historic data. We hypothesize that this increase may be due to selection favoring the melanistic morph in a changing forest environment.
Hermite-Hadamard-type inequalities for generalized trigonometrically and hyperbolic ρ-convex functions in two dimension
Authors: Dragomir Silvestru Sever , Jleli Mohamed , Samet Bessem
Published: August 2024

In this article, we establish Hermite-Hadamard-type inequalities for the two classes of functions

X

±
λ

(

Ω

)

=

{

f
∈

C

2

(

Ω

)

:
Δ
f
±
λ
f
≥
0

}

{X}_{\pm \lambda }\left(\Omega )=\{f\in {C}^{2}\left(\Omega ):\Delta f\pm \lambda f\ge 0\}

, where

λ
>
0

\lambda \gt 0

and

Ω

\Omega

is an open subset of

R

2

{{\mathbb{R}}}^{2}

. We also obtain a characterization of the set

X

−
λ

(

Ω

)

{X}_{-\lambda }\left(\Omega )

. Notice that in the one-dimensional case, if

Ω
=
I

\Omega =I

(an open interval of

R

{\mathbb{R}}

) and

λ
=

ρ

2

\lambda ={\rho }^{2}

,

ρ
>
0

\rho \gt 0

, then

X

λ

(

Ω

)

{X}_{\lambda }\left(\Omega )

(resp.

X

−
λ

(

Ω

)

{X}_{-\lambda }\left(\Omega )

) reduces to the class of functions

f
∈

C

2

(

I

)

f\in {C}^{2}\left(I)

such that

f

f

is trigonometrically

ρ

\rho

-convex (resp. hyperbolic

ρ

\rho

-convex) on

I

I

.
Random walk algorithms for solving nonlinear chemotaxis problems
Authors: Sabelfeld Karl K. , Bukhasheev Oleg
Published: August 2024

Random walk based stochastic simulation methods for solving a nonlinear system of coupled transient diffusion and drift-diffusion equations governing a two-component chemotaxis process are developed.
The nonlinear system is solved by linearization, the system is evolved in time, by small time steps, where on each step a linear system of equations is solved by using the solution from the previous time step.
Three different stochastic algorithms are suggested, (1) the global random walk on grid (GRWG), (2) a randomized vector algorithm (RVA) based on a special transformation of the original matrix to a stochastic matrix, and (3) a stochastic projection algorithm (SPA). To get high precision results, these methods are combined with an iterative refinement method.
The slice sampler and centrally symmetric distributions
Authors: Planas Christophe , Rossi Alessandro
Published: August 2024

We show that the slice sampler generates Markov chains whose variables are mean independent and thus uncorrelated when the target density is centrally symmetric. Skewness instead boosts correlations. Popular implementation algorithms such as stepping-out and multivariate-sampling-with-hyperrectangles add statistical inefficiency, the first in case of multimodality, the second in all circumstances. A new sampler which exploits these structural and algorithmic characteristics to reduce the variance of Monte Carlo estimates is experimented in several sampling problems. An insight into the properties of the product slice sampler is also provided.
Integrating deep convolutional surrogate solvers and particle swarm optimization for efficient inverse design of plasmonic patch nanoantennas
Authors: Hemayat Saeed , Moayed Baharlou Sina , Sergienko Alexander , Ndao Abdoulaye
Published: August 2024

Plasmonic nanoantennas with suitable far-field characteristics are of huge interest for utilization in optical wireless links, inter-/intrachip communications, LiDARs, and photonic integrated circuits due to their exceptional modal confinement. Despite its success in shaping robust antenna design theories in radio frequency and millimeter-wave regimes, conventional transmission line theory finds its validity diminished in the optical frequencies, leading to a noticeable void in a generalized theory for antenna design in the optical domain. By utilizing neural networks, and through a one-time training of the network, one can transform the plasmonic nanoantennas design into an automated, data-driven task. In this work, we have developed a multi-head deep convolutional neural network serving as an efficient inverse-design framework for plasmonic patch nanoantennas. Our framework is designed with the main goal of determining the optimal geometries of nanoantennas to achieve the desired (inquired by the designer) S
11 and radiation pattern simultaneously. The proposed approach preserves the one-to-many mappings, enabling us to generate diverse designs. In addition, apart from the primary fabrication limitations that were considered while generating the dataset, further design and fabrication constraints can also be applied after the training process. In addition to possessing an exceptionally rapid surrogate solver capable of predicting S
11 and radiation patterns throughout the entire design frequency spectrum, we are introducing what we believe to be the pioneering inverse design network. This network enables the creation of efficient plasmonic antennas while concurrently accommodating customizable queries for both S
11 and radiation patterns, achieving remarkable accuracy within a single network framework. Our framework is capable of designing a wide range of devices, including single band, dual band, and broadband antennas, with directivities and radiation efficiencies reaching 11.07 dBi and 75 %, respectively, for a single patch. The proposed approach has been developed as a transformative shift in the inverse design of photonics components, with its impact extending beyond antenna design, opening a new paradigm toward real-time design of application-specific nanophotonic devices.
Fully renewable oxygen barrier films of scCO2-processed thermoplastic starch/sugar alcohol blends
Authors: Luo Qian-li , Wang Zi-yu , Ma Ning , Xu Hong-juan , Huang Ya-qiong , Yeh Jen-taut
Published: August 2024

Excellent oxygen barrier films were prepared by blending very small loadings (<1 wt%) of dihydroxyacetone (DHA), erythritol (ET) or xylitol (XT) in thermoplastic starch (TPS), and/or processing with supercritical carbon dioxide (scCO2) assistance. The minimum oxygen transmission rates (OTR) and all free-volume-hole characteristic (FVH) values of each scCO2-processed TPS/sugar alcohol film series are somewhat smaller than those of corresponding TPS/sugar alcohol film series without scCO2-assistance, and decrease with the decrease in sugar alcohol’s molecular weight. The minimum OTR values acquired for scCO2-processed TPS/DHA and TPS/ET blown films are only 3.6 and 4.3 cm3/m2·day·atm, respectively, which meet the demand of high oxygen barrier films having OTR ≦5 cm3/m2·day·atm. The longitudinal or transversal tensile strengths acquired for each scCO2-processed TPS/sugar alcohol series films are ∼30 % to ∼40 % higher than those of the TPS blown films. Dynamic mechanical relaxations of each TPS/sugar alcohol or scCO2-processed TPS/sugar alcohol film series reveal that the sugar alcohols are compatible with TPS, as their sugar alcohol contents are ≤ the corresponding compatibility values. The decreased OTR and FVH values acquired for TPS/sugar alcohol or scCO2-processed TPS/sugar alcohol films are most likely due to them being scCO2-processed or incorporated with smaller molecular weight of sugar alcohols.
A review of confined impinging jet reactor (CIJR) with a perspective of mRNA-LNP vaccine production
Authors: Zhao Le , Xu Zhiyun , Li Hua , Liu Lu , Chen Songying , Peng Zhengbiao , Wang Guichao
Published: August 2024

In the spotlight of successful breakthrough of the COVID-19 mRNA vaccines, lipid nanoparticles are becoming an important vehicle to deliver a variety of therapeutics. The encapsulation of mRNA using lipids is a self-organizing process that necessitates fast mixing to achieve uniform supersaturation. This is achieved in a confined impinging jet reactor (CIJR) where two input jets collide and fast mix in the mixing chamber. While CIJR is not a new mixing technology, it stands out for its capability to achieve mixing times below a millisecond. This study presents a critical review of major studies concerning CIJRs, starting with the CIJRs’ structures and flow characterization, through experimental and numerical studies, and closing with successful applications in a wide range of chemical/pharmaceutical processes. The detailed mixing principles, scaling-up, and mechanisms of making nanoparticles are discussed focusing mainly on the hydrodynamic aspect. The objective of the review is to supply essential information for the optimized design and operation of CIJRs, catering to both industry and academia.
Phytochemical profile and antioxidant capacity of the endemic species Bellevalia sasonii Fidan
Authors: Tekіn Metin , Kuru İbrahim Selçuk
Published: August 2024

The study investigated total phenolic-flavonoid content, antioxidant activity, and phytochemical compounds across various parts (bulb, stem, leaf, and flower) of the endemic Bellevalia sasonii, commonly known as hyacinth, belonging to the Asparagaceae family. Phenolic content was highest in bulb extracts (117.28 μg GAE) and lowest in stems (45.11 μg GAE). Conversely, leaf extracts exhibited the highest flavonoid content (79.44 μg QEs), while stems showed the lowest (22.77 μg QEs). When the antioxidant activities were compared, by DPPH method leaf = flower > bulb > stem; in ABTS and CUPRAC methods bulb > flower > leaf > stem, respectively. Considering the results in general, it was revealed that bulbs and flowers displayed higher activity, while stem exhibited lower activity compared to other parts. The phytochemical analysis identified 53 active substances, with 27 absent in any extract and 15 detected across all extracts. The distribution of phytochemicals varied among parts, with bulbs, stems, flowers, and leaves also different numbers. The LC-MS/MS analysis revealed prominent metabolites including fumaric acid in leaves, caffeic acid in bulbs, and cosmosiin and quinic acid in flowers. This study provides foundational insights into B. sasonii, an important endemic plant in Türkiye, laying the groundwork for future research on its medicinal and ecological roles.
Self-Reported ICD-11 Personality Disorder Severity in Peruvian Adolescents: Structure, Validity, and Tentative Cutoffs
Authors: Hualparuca-Olivera Luis , Calle-Arancibia Margarita , Caycho-Rodríguez Tomás , Bach Bo
Published: August 2024

Personality disorder (PD) is particularly common in adolescents, which underscores the significance of early screening, diagnosis, and intervention. To date, the definition of PD in the new ICD-11 has not yet been investigated in adolescents. This study therefore aimed to investigate the unidimensionality and criterion validity of self-reported ICD-11 PD features in Peruvian adolescents using the Personality Disorder Severity ICD-11 (PDS-ICD-11) scale. A total of 1,073 students (63% female; age range 12-16 years) were administered the PDS-ICD-11 scale along with criterion measures of personality pathology and symptom distress. The PDS-ICD-11 score showed adequate unidimensionality and conceptually meaningful associations with external criterion variables. The findings indicate that ICD-11 PD features, as measured with the PDS-ICD-11 scale, are structurally and conceptually sound when employed with adolescents. Norm-based cutoffs derived from the present study may be used for clinical interpretation. The PDS-ICD-11 may be employed as an efficient screening tool for personality dysfunction in adolescents.
AUTORIA E AUTORALIDADE: O MOVIMENTO PARATÓPICO DE UM PSEUDÔNIMO
Authors: Ribeiro Carreira Rosangela Aparecida , Nascimento Jarbas Vargas
Published: August 2024

Este trabalho objetiva tratar da questão da utilização do pseudônimo como forma de valorização do dizer e favorecimento de questões ideológicas de forma paratópica com o intuito de demonstrar como a autoria pode ser sustentada paratopicamente com a utilização de um pseudônimo, embasando-se, principalmente, na Análise do Discurso (AD) de Linha Francesa na obra de Maingueneau (2008-2010), aplicando-a na obra de José do Nascimento de Moraes[1], quando da utilização de seu pseudônimo Valério Santiago na obra Puxos e Repuxos (1910) como ponto de partida para reflexões futuras sobre autoria e AD com relação a pseudônimos. Trata-se do primeiro movimento de comunicação para a comunidade acadêmica de parte da pesquisa de doutorado desenvolvida sob o título “A paratopia testemunho-documental e o discurso da negritude em Vencidos de Degenerados”, na qual essa temática surge rapidamente no estudo da obra completa do autor como possibilidade para trabalhos futuros. Nesta análise em particular, demonstra-se que há estratégias de deslizamento, ancoragem e apagamento do autor na construção da imagem de autor dada a Valério Santiago.Palavras-chave: Autoria; pseudônimo; discurso; paratopia.
Patrimônio, memória, tradição, etc: discussão de algumas situações francesas da relação com o passado
Authors: Tornatore Jean-Louis
Published: August 2024

Patrimônio, memória, tradição, etc: discussão de algumas situações francesas da relação com o passado
A dimensão simbólica do design através da representação de mulheres em reclames do Laboratório do Parque Souza Soares (Pelotas/RS)
Authors: Lima Paula Garcia
Published: August 2024

A dimensão simbólica do design através da representação de mulheres em reclames do Laboratório do Parque Souza Soares (Pelotas/RS)
O Paradigma da Reconstituição – a prática do restauro no século XIX
Authors: Rodrigues Paulo Simões
Published: August 2024

O Paradigma da Reconstituição – a prática do restauro no século XIX
A Coleção Marina de Moraes Pires no Arquivo Fotográfico Memória da UFPel: a imbricada história de uma diretora e sua escola
Authors: Michelon Francisca Ferreira , Schmitt Daniela
Published: August 2024

A Coleção Marina de Moraes Pires no Arquivo Fotográfico Memória da UFPel: a imbricada história de uma diretora e sua escola
O lugar da lembrança. Reflexões sobre a teoria da memória coletiva em Paul Ricoeur
Authors: Barash Jeffrey Andrew
Published: August 2024

O presente estudo se dedica a examinar o conceito de memóriacoletiva interrogando-se a respeito da interpretação proposta por Paul Ricoeurem sua obra A memória, a história, o esquecimento O autor apresenta umaleitura crítica da interpretação da memória coletiva em Ricoeur quando estebusca compreender o fenômeno por analogia à memória pessoal e assume orisco, segundo essa leitura, de ocultar as dimensões da memória coletiva queescapam a tal relação analógica. O autor busca então ultrapassar o quadrodessa analogia por uma análise das fontes simbólicas e metapessoais damemória coletiva.Palavras-chave: memória coletiva, símbolo,Paul Ricoeur
ASSESSING DIFFERENCES IN US AND EU APPROACHES TO CONTAINING IRAN’S NUCLEAR AMBITIONS
Authors: Bobkin Nikolay ,   Georgy Arbatov Institute for U.S. and Canada Studies
Published: August 2024

Between 2003 and 2022, European Union (EU) Iran policy was the result of constant course corrections made by EU institutions and member states to contain Iran’s nuclear program. The article makes an attempt to bring some clarity to the differences between Europe and the United States in approaches to the implementation of the 2015 nuclear agreement. This topic is relevant because recent research has focused on the progress of the Joint Comprehensive Plan of Action (JCPOA) rather than on the political process of international resolution of the decades-long Iranian nuclear crisis. The article begins by examining the historical background behind European policy toward the Islamic Republic of Iran, then examines how the U.S. withdrawal from the nuclear agreement undermined European efforts to normalize relations with Tehran, and third, assesses the differences in approaches between the Biden administration and EU to revive the JCPOA. The analysis showed that various initiatives taken by the EU to protect the Iran nuclear agreement did not lead to the expected results due to constant pressure from Washington. However, the conclusion is that transatlantic convergence on the Iranian issue remains much stronger than it appears, even despite disagreements over the Iranian nuclear program. The EU and the US are united in their negative attitude towards the Iranian missile program, regional politics and the human rights situation in Iran.
Nanofibers for Drug Delivery: Design and Fabrication Strategies
Authors: Kalayil Nisha , Budar Aarati Anil , Dave Roshan Kalulal
Published: August 2024

Nanotechnology is an emerging field with substantial scientific and economic potential globally. Researchers are increasingly focusing on creating nanomaterials for diverse applications. This review explores the potential of drug-loaded nanofibers for drug delivery and describes their production methods, including centrifugal jet spinning, plasma-induced synthesis, solution blow spinning (SBS), pressure spinning, and electrospinning. Nanofibers, owing to their extensive surface area relative to their volume, are believed to enhance interactions with target substances and therefore are valuable in numerous applications. This review provides a thorough exploration of fabrication techniques, encompassing fundamental concepts, methods, and material aspects. Furthermore, it provides perspectives on the variables affecting the production and application of nanofibers, such as electrospinning parameters (including electric field intensity, needle size, flow rate, and distance between the needle and collector), solution characteristics (such as polymer concentration, solvent type, conductivity, and viscosity), and environmental factors (such as temperature and humidity). Additionally, an extensive compilation of patents related to nanofiber-based drug delivery systems is presented, showcasing innovations and advancements in the field. The review also examines current clinical trials involving nanofiber technologies, providing insights into their therapeutic potential and translational prospects. This review is aimed at presenting an overview of nanofiber drug delivery systems, and identifying future opportunities and challenges in their development and application.
La pedagogía crítica universitaria: Encuentros educativos interculturales entre la Universidad Nacional y la comunidad de Kachabri, en Costa Rica
Authors: Gómez-Torres Juan Rafael
Published: August 2024

Aim.To underscore the necessity of revising university pedagogy at the National University of Costa Rica (UNA). Discussion. Effective teaching and learning require stepping out of our comfort zones. This involves contextualization and practical application of theories. Therefore, intercultural educational tours are promoted as a didactic approach to develop and evaluate theoretical content of courses related to concepts of distinction, diversity, difference, and exteriority as an ethical proposal and policy. These field trips should be integrated across various courses to promote positive interactions, balance with nature, social justice, and the appreciation of various cosmogonies. Conclusion. The essay concludes by presenting the perspectives of students who have undergone these formative experiences. These students emphasize the significance of such experiences in enhancing educational processes that foster human awareness and connection with nature, integrating them as essential components within various university curricula.
authors at both sides of the list
Authors: Баранчиков Ю.Н.
Published: August 2024

Хотя официальных и постоянных критериев для определения положения вашей фамилии в списке авторов статьи не существует, все чаще в медико-биологических публикациях применяется принцип «крайних авторов». Наилучшим дополнением к нему будет подробное указание вклада каждого автора в создание статьи.

Although there are no official and permanent criteria for determining the position of your name in the list of authors of an article, the principle of “authors at the both sides of the list” is increasingly used in biomedical publications. The best addition to it is a detailed indication of the contribution of each author to the creation of the article.
CARBON FLOWS IN THE ECOSYSTEMS OF THE MIDDLE TAIGA OF CENTRAL SIBERIA
Authors: Панов А.В. , Махныкина А.В. , Урбан А.В. , Зырянов В.И. , Полосухина Д.А. , Кукавская Е.А. , Арясов В.Е. , Колосов Р.А. , Путилин И.Р. , Третьяков П.Д. , Трусов Д.В. , Садыков Р.Т. , Прокушкин А.С.
Published: August 2024

Наблюдаемый рост температуры, вызванный увеличением концентраций климатически активных (парниковых) газов в атмосфере, в первую очередь диоксида углерода (CO2) и метана (CH4), может быть причиной прогнозируемого высвобождения углерода, аккумулированного за тысячелетия на обширных территориях северных широт. Масштабы и длительность ожидаемого эффекта остаются открытым вопросом, что обусловлено спорадичностью количественных оценок потоков углерода. В работе отражены текущий статус, направления и основные результаты многолетних инструментальных исследований потоков углерода в экосистемах подзоны средней тайги Центральной Сибири, на базе Средне-Енисейского стационара Института леса им. В. Н. Сукачева СО РАН (обсерватории ZOTTO). Представлена динамика концентрации СО2и CH4в атмосфере с 2009 по 2020 г. Приведены данные чистого экосистемного обмена СО2для лесоболотных комп­лексов, свидетельствующие, что они выступают поглотителем (стоком) СО2атмосферы. Для репрезентативных экосистем дана оценка почвенных эмиссионных потоков СО2и сезонный ход фотосинтетической ассимиляции углерода доминантами подчиненного яруса растительности. Выявлены закономерности поведения растворенных форм углерода в водах ручьев, дренирующих олиготрофный и эвтрофный болотные массивы в районе исследований, представлены показатели эмиссии СО2с водной поверхности.

The observed increase in temperature, caused by increasing concentrations of climate-active (greenhouse) gases in the atmosphere, primarily carbon dioxide (CO2) and methane (CH4), may be responsible for the projected release of carbon accumulated over millennia in large areas of northern latitudes. The scale and duration of the expected effect remains an open question, due to the sporadic nature of quantitative estimates of carbon flows. The work reflects the current status, directions and main results of long-term instrumental studies of carbon flows in the ecosystems of the middle taiga subzone of Central Siberia, on the basis of the Middle Yenisei experimental station of V. N. Sukachev Institute of Forest, Siberian Branch of the Russian Academy of Sciences (ZOTTO observatory). The dynamics of CO2and CH4concentrations in the atmosphere from 2009 to 2020 are presented. The values of net ecosystem exchange of CO2for forest-swamp complexes are given, indicating that they act as a sink (sink) of atmospheric CO2. For representative ecosystems, an assessment of soil CO2emission fluxes and the seasonal variation in the values of photosynthetic carbon assimilation by dominants of the subordinate vegetation layer are presented. The patterns of behavior of dissolved forms of carbon in the waters of streams draining oligotrophic and eutrophic swamps in the study area were revealed, and the values of CO2emission from the water surface were presented.
LIME TREE IN THE ARBORETUM OF V. N. SUKACHEV INSTITUTE OF FOREST, SIBERIAN BRANCH, RUSSIAN ACADEMY OF SCIENCES EXPERIMENTAL STATION «POGORELSKIY BOR»
Authors: Седаева М.И.
Published: August 2024

В дендрарии экспериментального хозяйства Института леса им. В. Н. Сукачева СО РАН «Погорельский бор» произрастают деревья двух видов лип: европейский вид – липа мелколистная (Tilia cordataMill.) и дальневосточный – л. амурская (T. amurensisRupr.). Высота липы мелколистной 9–16 м, диаметр ствола – 10–36.5 см, л. амурской – соответственно 11.5–14.5 м и 7.5–21.5 см. Растения обоих видов характеризуются высокой зимостойкостью, не повреждаются весенними заморозками и мало заселяются вредителями. Зацветают липы в середине июля при достижении суммы эффективных температур около 800 градусо-дней (42.2–43.0 % от общей tэф> 5 за год) и продолжают цветение в течении 10–17 дней. Плоды-орешки созревают в сентябре. У липы мелколистной орешки имели длину 5.7 мм, ширину 4.4 мм и массу 1000 шт. 23.6 г, семена – соответственно 4.0 мм, 3.0 мм и 14.5 г., у л. амурской эти показатели имели близкие значения – 5.3 мм, 3.9 мм и 23.8 г для орешков, 3.9 мм, 2.6 мм и 16.1 г для семян. Доля пустых семян у липы мелколистной 70 %, а у л. мурской – 30 %. При этом доброкачественность образцов семян обоих видов не превышала 30 %. На территории дендрария имеется естественное возобновление липы, в том числе и семенное. Наиболее обильно оно на расстоянии 50–100 м от материнских растений, где его плотность составляет 25–41 шт./м2.

Two lime tree species: European – small-leaved lime (Tilia cordata Mill.) and Far Eastern – amur lime (Tilia amurensisRupr.) grow in the arboretum of V. N. Sukachev Institute of Forest, Siberian Branch, Russian Academy of Sciences experimental station «Pogorelskiy Bor». Small-leaved lime tree has 9–16 m in height and 10–36.5 cm in diameter, amur lime tree has 11.5–14.5 m and 7.5–21.5 cm, accordingly. Plants of both species are characterized by high winter hardiness, they are not damaged with spring frosts and rarely attacked by pests. The lime trees begin blooming in the middle of July when the sum of effective temperatures reaches about 800 degrees/day (42.2–43.0 % of the total tef> 5 for the year). They continue blooming during 10–17 days. A fruits – lime-capsules ripen in September. The small-leaved lime tree capsules were 5.7 mm in length, 4.4 mm in width and 23.6 g in weight per 1000 pieces, its seeds were 4.0 mm, 3.0 mm and 14.5 g, accordingly. Sizes of amur lime tree capsules and seeds were similar – 5.3 mm, 3.9 mm and 23.8 g for the first ones and 3.9 mm 2.6 mm and 16.1 for the second ones. The part of empty seeds in small-leaved lime tree was 70 % but the part of such seeds in amur lime tree was 30 %. At the same time, the good quality of seed samples of both species did not exceed 30 %. On the territory of the arboretum there is natural regeneration of lime tree, including self-seeding. It is the most abundant at a distance of 50–100 m from the mother plants, where its density is 25–41 pieces per square meter.
Gobernanza electrónica como compleja alternativa de eficiencia administrativa en Gobiernos locales: revisión sistemática de literatura
Authors: Muñoz Castañeda Laura Susana , Quiñones Li Aura Elisa , Sifuentes Pinto Nilsa
Published: August 2024

Public administration, anchored in hierarchies and bureaucracies, demands the decentralization and modernization of activities and tools; therefore, the new information and communication technologies brought about by electronic governance play a crucial role in the analysis and delivery of government results. The purpose of this study was to comprehend the contribution of this governance in local governments through a systematic review of 22 investigations available between 2019 and 2023. This review was conducted using a qualitative approach and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart method. It was identified that regional and local governments within the Public Administration consider physical presence essential for making decisions, communicating information, and correcting failures, with the aim of maintaining government coherence. This approach emphasizes the importance of personalizing care and solutions to ensure equitable participation in state processes. The research revealed that electronic governance is crucial for improving the efficiency of local governments, highlighting the need for effective resource management and the essential role of managers in the implementation of effective and adaptive government practices.
Specific differences in the approach to the use of old testament imagery in early Christian exegesis and iconography
Authors: Nesterova Olga
Published: August 2024

One of the peculiarities of early Christian art was its regular recourse to stories and images borrowed from Old Testament history. Art historians reasonably assume that the use of such images could not have been purely illustrative, and that such images contained a message addressed directly to the Christian flock and available for their understanding, yet not verbalised and therefore not always comprehensive for modern interpreters. Meanwhile, a similar task of an actualising reinterpretation of the content of the Hebrew Scriptures has been successfully accomplished by the so-called typological exegesis, which allowed to consider the characters and events of Old Testament history as "types" (that is, as images that symbolically and prophetically foreshadow the events and realities of the New Testament era) and the entire Old Testament as a prophetic foretelling of the coming of Christ, taught in a mysterious form. It is therefore in the experience of typological exegesis that researchers most often seek the key to understanding the role of Old Testament motifs in Paleo-Christian iconography. However, the formal reference to the existence of a stable tradition of typological interpretation of biblical texts, conveyed to the faithful through catechetical instructions and homilies, does not provide sufficiently convincing grounds for the claim that early Christian iconography, when dealing with Old Testament themes, was guided by these interpretations in the choice of depicted subjects, in assuming that they would be perceived by believers in a specified typological sense. The article deals with the main features of Christian typological exegesis, which did not reduce itself to attributing symbolic meanings to the images of Old Testament history that could be mechanically transferred to the pictorial plane. The internal logic of the development of typological interpretations has been a function of the tasks to which they were subject. The typology, which emerged as instrument of anti-Jewish polemics, sought to prove the messianic role of Jesus Christ as the Son of God, who offered himself as a sacrifice for the atonement of original sin, and the victory of the Christian Church as the new people of God. Both the range of subjects interpreted and the meanings assigned to them, as well as the nature of the connections established between them, were determined in accordance with these objectives. The article shows that these features, which determined the specificity of typological interpretations, were not reflected in the early Christian iconography, the main task of which was to strengthen the trust of the faithful in the salvation and eternal life granted by God. The fundamental difference between the early Christian exegetical and iconographic traditions is especially evident in the different ways in which the same biblical motifs are treated, suggesting that these traditions developed in parallel but independently of each other, even though they had common origins.
Sobre el proceso de formación continua del Estado y las estrategias para estudiar sus configuraciones locales: un aporte teórico-metodológico para la discusión
Authors: Lázaro Parra Andrés Felipe
Published: August 2024

El presente artículo tiene como finalidad presentar el enfoque de formación continua del Estado como una alternativa viable y relevante en el desarrollo de los estudios contemporáneos de este dicho fenómeno. Para tal objetivo, el artículo aborda inicialmente una revisión somera de algunos de los estudios más recientes que sobre el fenómeno estatal se han desarrollado desde el ámbito de las ciencias sociales latinoamericanas, buscando agruparlos por enfoques y estableciendo sus alcances y limitaciones. Seguidamente se enfatiza en los linderos teóricos del enfoque referido, explicando su utilidad para estudiar las configuraciones locales del Estado. Finalmente se establecen claves metodológicas que ayudan a rastrear estas formas novedosas que adquiere la estatalidad, y se dan unas conclusiones generales.
Visiones y transformaciones del Estado, la sociedad y lo público en América Latina: insistir en las preguntas por el Estado
Authors: Piedrahita-Arcila Irene
Published: August 2024

El Estado es uno de esos objetos de investigación que causa incomodidad en las ciencias sociales y en la ciencia política. A pesar de que es virtualmente imposible negar su importancia, la incomodidad suele radicar en preguntas tales como ¿qué tan necesario es el Estado?, ¿qué posibilidades hay de una vida social “más allá del Estado”?, o bien, si ¿su estudio ya está agotado? Y, por ende, ¿sería mejor abandonarlo y focalizar la mirada en otros temas?, ¿en otras preguntas?, ¿en otros objetos? Sin embargo, el Estado vuelve a emerger en las investigaciones.
Anarchist Anti-statism and the Colonial Question in Cuba, 1898-1902
Authors: Cleminson Richard , Doyle Alex
Published: August 2024

This article examines a specific case study —the issues arising from Spanish colonialism and later U.S. imperialism— on Cuba at the turn of the nineteenth century through the lens of the working-class movement of anarchism. Anarchists in Cuba, many of whom were Spanish émigrés, argued that true emancipation came not from patriotism, nationalism and the political form of the state, but through self-organization and the transformation of “the social”. Tensions arose, however, within anarchist newspapers, upon which this article draws extensively, as to whether the pursuance of nationhood was an interim stage in this development or a trap offered by the bourgeois classes to domesticate workers’ demands. The state, nevertheless, was consistently rejected as a desirable medium or end destination.
REDUCTION OF POTENTIAL RADIOLOGICAL RISKS FOR PATIENTS UNDERGOING DIAGNOSTIC EXAMS THROUGH MODIFICATION OF THE X-RAY SPECTRUM
Authors: Cruz Delgado José Santa , Márquez Pachas Fernando , Gonzales-Ccoscco Alberto E. , Carrasco Solís Eduardo , Herrera Castillo Carlos , Patiño Camargo Galo , Alva-Sánchez Mirko
Published: August 2024

The diagnostic medical practice using X-rays significantly contributes to the collective dose worldwide, where the inherent risk in each examination is proportional to the absorbed dose, which is related to deterministic and stochastic effects of ionizing radiation. Therefore, due to the necessity of optimizing each radiological procedure, this study aimed to reduce the absorbed dose in patients undergoing X-ray examinations by evaluating each parameter that modifies the spectral distribution. The Birch and Marshall method was employed to reconstruct and modify the X-ray spectra based on tube voltage, filtration, tube current, anode angle, and energy fluence modulation. By modifying these parameters, it was possible to reduce the absorbed dose in the patient’s skin by up to 38%. The proposed methodology is feasible for implementation in clinical centers, given the availability of copper filters incorporated into X-ray equipment. Additionally, an alternative technique involving tantalum filters is presented, achieving a reduction in absorbed dose of up to 57%. Thus, with the developed methodology, it is demonstrated that it is possible to reduce radiation doses by modifying spectral distributions, reproducing medical images with a significant reduction in the absorbed dose to the patient, while ensuring quality and safety in X-ray diagnostic procedures.
Impact of the simultaneous integration of DER, DR, and BES strategies in a distribution network
Authors: Martinez Peñaloza Alejandra , Duarte César , Osma Pinto German
Published: August 2024

The massive integration of distributed energy resources into electricity networks has produced impacts on voltage profiles and power losses, among others. Nevertheless, demand response programs or energy saving strategies in buildings are initiatives used to improve the demand profile. Therefore, this paper seeks to analyze the impact of the simultaneous integration of distributed energy resources, demand response programs and energy saving strategies in buildings in a distribution network. A co-simulation in Python and PowerFactory is used to simulate operating scenarios automatically. As a result, the simultaneous integration of the initiatives favors parameters such as voltage levels, power losses and transformer loading. However, it is necessary to set limits on the integration of resources to avoid affecting the operation of electricity networks.
Secondary Control Strategy without Communications for Unbalanced Isolated Microgrids
Authors: Salinas Cala Andres Mauricio , Rey López Juan Manuel , Mantilla Villalobos María Alejandra
Published: August 2024

In the context of the energy transition, electrical microgrids have become a key energy solution for isolated zones. For this type of application, low-voltage networks with unbalanced loads are commonly connected. Despite this, many of the hierarchical control strategies presented in the literature have been designed to operate properly only in the presence of balanced loads. For this reason, it is relevant to study how control strategies can be adapted to this scenario, especially those that reduce the dependence on communications to enhance flexibility and reliability. In this sense, this paper presents a secondary layer control strategy that does not require the use of communications to operate in isolated microgrids with unbalanced loads. The strategy guarantees proper performance in terms of power-sharing between the distributed generators of the microgrid. Simulations on Matlab/Simulink are presented to validate the response of proposal.
Operación de microrredes hidro +solar: estado del arte contextualizado al departamento del Chocó.
Authors: Terreros Barreto Jhon Ronald , Garcés Ruiz Alejandro
Published: August 2024

Colombia tiene un gran potencial tanto de generación hidroeléctrica, así como de generación solar fotovoltaica. Por tanto, las soluciones de microrredes (solar+hidro) constituye una oportunidad para electrificar zonas no interconectadas. El control y la operación son dos de los mayores retos en el funcionamiento adecuado de este tipo de microrredes debido a la mezcla de dinámicas rápidas y de baja inercia asociada a los recursos solares, con dinámicas mecánicas lentas asociadas a los sistemas hidroeléctricos. El presente trabajo presenta los avances y el estado del arte de las microrredes (solar+hidro) y su posible aplicación en zonas no interconectadas de Colombia, específicamente para un municipio piloto del departamento del Chocó. Se presenta tanto la tecnología de micro-central hidroeléctrica como de generación hidrocinética como tecnologías clave para los ríos caudalosos ubicados en estas zonas no-interconectadas.