bluuebunny/crossref_metadata_2025 huggingface dataset:
Medicolegal implications and regulatory frameworks of regenerative orthopaedics - A systematic review
Authors:   ACS Medical College and Hospital, Dr MGR Educational and Research Institute, Paul Prince M , Jeyaraman Madhan , Nallakumarasamy Arulkumar , Jeyaraman Naveen , Khanna Manish
Published: April 2023

Review question / Objective: Analyzing the literature and data on medicolegal implications, issues, and challenges of regenerative orthopaedics globally as well as in India. P – Published literature on medicolegal implications and regulatory frameworks on regenerative orthopaedics. I – Regenerative therapies in orthopaedics. C – No comparator group. O – Medical legal implication of regenerative orthopaedics. Condition being studied: Medicolegal implications and regulatory frameworks in regenerative orthopaedics.
FEATURES OF THE FORMATION OF THE PRODUCTION STRATEGY
IN MODERN CONDITIONS
Authors: Bondarenko Т. N.
Published: April 2023

This article discusses the main features of the formation of the production strategy and technical policy of modern enterprises. The main directions of its development are determined taking into account the new economic conditions.
INCREASING LABOR PRODUCTIVITY: CHALLENGES AND ACHIEVEMENTS
Authors: Biryukova L. V.
Published: April 2023

The article is devoted to the study of the problem of increasing labor productivity for the purposes of ensuring sustainable economic development of modern Russia. The factors of labor productivity growth are determined; the results of the implementation of the national project "Labor Productivity" on the example of the Khabarovsk Territory are investigated. The reasons constraining the growth of labor productivity are revealed.
PLANNING OF MARKETING ACTIVITIES OF A SERVICE COMPANY
Authors: Zimin A. S.
Published: April 2023

Services as an intangible asset play a significant role in the field of socio-economic development. Currently, the service sector, like many other business sectors in the Russian Federation, is undergoing serious changes. The trends of its development are determined by the influence of factors of the marketing macro- and microenvironment of functioning. At this stage of the development of the market system, success can accompany only those companies that clearly understand the specifics of the formation of the marketing environment of the company, and are also engaged in improving the planning system in this area. The article discusses the experience of developing a marketing plan for catering enterprises of LLC "Signor Tomato", Khabarovsk.
ORGANIZATION OF PUBLIC POWER IN THE SUBJECTS
OF THE RUSSIAN FEDERATION
Authors: Lebedeva Yu. N.
Published: April 2023

The relevance of the topic of the article is due to the current state of public authorities and local self-government in the context of the adoption of a new federal law on the general principles of the organization of public power in the subjects of the Russian Federation. The changes in the regulations on municipal government are characterized.
The Hα Luminosity Function of Galaxies at z ∼ 4.5
Authors: Bollo Victoria , González Valentino , Stefanon Mauro , Oesch Pascal A. , Bouwens Rychard J. , Smit Renske , Illingworth Garth D. , Labbé Ivo
Published: April 2023

We present the Hα luminosity function (LF) derived from a large sample of Lyman break galaxies at z ∼ 4.5 over the GOODS-South and North fields. This study makes use of the new, full-depth Spitzer/IRAC [3.6] and [4.5] imaging from the GOODS Re-ionization Era wide-Area Treasury from the Spitzer program. The Hα flux is derived from the offset between the continuum flux estimated from the best-fit spectral energy distribution, and the observed photometry in IRAC [3.6]. From these measurements, we build the Hα LF and study its evolution providing the best constraints of this property at high redshift, where spectroscopy of Hα is not yet available. Schechter parameterizations of the Hα LF show a decreasing evolution of Φ∗ with redshift, increasing evolution in L
∗, and no significant evolution in the faint-end slope at high z. We find that star formation rates (SFRs) derived from Hα are higher than those derived from the rest-frame UV for low SFR galaxies but the opposite happens for the highest SFRs. This can be explained by lower mass galaxies (also lower SFR) having, on average, rising star formation histories (SFHs), while at the highest masses the SFHs may be declining. The SFR function is steeper, and because of the excess SFR(Hα) compared to SFR(UV) at low SFRs, the SFR density estimated from Hα is higher than the previous estimates based on UV luminosities.
Multifluid Simulations of Upper-chromospheric Magnetic Reconnection with Helium–Hydrogen Mixture
Authors: Wargnier Q. M. , Martínez-Sykora J. , Hansteen V. H. , De Pontieu B.
Published: April 2023

Our understanding of magnetic reconnection (MR) under chromospheric conditions remains limited. Recent observations have demonstrated the important role of ion–neutral interactions in the dynamics of the chromosphere. Furthermore, the comparison between the spectral profiles and synthetic observations of reconnection events suggests that current MHD approaches appear to be inconsistent with observations. First, collisions and multithermal aspects of the plasma play a role in these regions. Second, hydrogen and helium ionization effects are relevant to the energy balance of the chromosphere. This work investigates the multifluid multispecies (MFMS) effects on MR in conditions representative of the upper chromosphere using the multifluid Ebysus code. We compare an MFMS approach based on a helium–hydrogen mixture with a two-fluid MHD model based on hydrogen only. The simulations of MR are performed in a Lundquist number regime high enough to develop plasmoids and instabilities. We study the evolution of the MR and compare the two approaches including the structure of the current sheet and plasmoids, the decoupling of the particles, the evolution of the heating mechanisms, and the composition. The presence of helium species leads to more efficient heating mechanisms than the two-fluid case. This scenario, which is out of reach of the two-fluid or single-fluid models, can reach transition region temperatures starting from upper-chromospheric thermodynamic conditions, representative of a quiet Sun scenario. The different dynamics between helium and hydrogen species could lead to chemical fractionation and, under certain conditions, enrichment of helium in the strongest outflows. This could be of significance for recent observations of helium enrichment in the solar wind in switchbacks and coronal mass ejections.
A new trapdoor spider of Cyclocosmia Ausserer, 1871 from southern China (Araneae, Halonoproctidae)
Authors: Yu Kun , Li Changze , Zhang Shuyuan , Zhang Feng
Published: April 2023

The genus Cyclocosmia Ausserer, 1871 previously included ten species from North America and Asia, six of which have been recorded from China.

A new species, Cyclocosmia ruyi Yu & Zhang sp. n., is described and diagnosed, based on both sexes from Guangxi Province, China. Morphological characters for the early stages of juveniles of the new species are also provided.
Une géographie du recrutement des maîtres de conférences en France : trajectoires des candidats et spatialisation des recrutements
Authors: Alamel Alexis , Marega Oumar
Published: April 2023

Au cours des trois dernières décennies, les réformes successives opérées dans l’enseignement supérieur et la recherche (ESR) ont transformé le paysage universitaire français. L’augmentation du nombre d’universités et d’antennes universitaires avait pour but de répondre à la massification du nombre d’étudiants qui s’élèvent à 2,7 millions en 2020, soit une hausse de 26 % entre 2000 et 2020. Toutefois, cette croissance du public estudiantin ne s’est pas nécessairement accompagnée d’une hausse du nombre de postes d’enseignants chercheurs (EC) titulaires. Se focalisant sur les sections 23 (géographie) et 24 (aménagement-urbanisme) du Conseil national des universités (CNU), cet article propose une lecture spatialisée du recrutement des maîtres de conférences (MCF) entre 2013 et 2020. En exploitant les données fournies par le wiki des sections 23 et 24, 200 recrutements sont analysés. L’objectif de ce travail est de mettre en exergue les trajectoires (im-) mobiles des MCF recrutés, de proposer une géographie régionalisée et localisée des universités pourvoyeuses de futurs EC et de celles qui recrutent, et ceci dans un contexte de prise de poste de plus en plus tardive dans la carrière des individus. En conclusion, l’article élargit le débat sur la précarisation des postulants au corps de MCF en encourageant à l’étude des trajectoires individuelles et spatialisées de ces individus.
Une lettre inédite de Karl Marx à Jules Guesde sur la France, l’« Orient » et l’« Occident » (1879)
Authors: Ducange Jean-Numa
Published: April 2023

Les marxismes de Chine sont très peu pris en considération en France. Cet article expose quelques hypothèses expliquant cet état de fait et rappelle l’importance de la référence marxiste en Chine à tous les niveaux, des plus hautes instances de l’État à des intellectuels plus ou moins isolés. L’article suggère également quelques pistes pour une analyse marxiste des réalités chinoises aujourd’hui, multiformes, qui empêchent de dresser un état des lieux schématique de l’évolution contemporaine du pays (Chine « capitaliste » ou « socialiste », etc.). Il suggère, au-delà du présent dossier, de poursuivre des recherches sur ces multiples dimensions.
Ernst Bloch : le philosophe marxiste dissident de la RDA
Authors: Münster Arno
Published: April 2023

Converti au marxisme, en 1919, dans le sillage de György Lukacs, exilé, dès mars 1933, en fuyant le nazisme, en Suisse, en France, en République tchèque et finalement aux États-Unis (1938-1949), Ernst Bloch, auteur du Principe espérance , décide en février 1949 de retourner en Europe et d’accepter la chaire de professeur d’histoire de la philosophie que lui offrait l’Allemagne de l’Est, à l’université de Leipzig. Après avoir appuyé tout d’abord, dans ses conférences, non sans un certain enthousiasme, le projet de la « construction du socialisme », Ernst Bloch sera pourtant vite déçu de la politique des dirigeants de la RDA qui, comme Walter Ulbricht, étaient complètement alignés sur les positions de l’Union soviétique et imitaient, avec zèle, les méthodes staliniennes. Accusé de « révisionnisme » et de liens avec le groupe oppositionnel de W. Harich, préconisant une voie « allemande » et démocratique vers le socialisme, il sera interdit d’enseignement, dès avril 1957. Il quittera la RDA en août 1961, une semaine avant la construction du Mur de Berlin.
Aux sources de la marxologie : david riazanov et l’institut marx-engels
Authors: Dieuleveux Jean
Published: April 2023

En s’appuyant sur l’historiographie russe la plus récente, cet article retrace le parcours de l’académicien soviétique David Riazanov, de son premier engagement aux côtés des populistes russes à son exécution lors des grandes purges. L’article se concentre principalement sur la contribution essentielle de Riazanov à la fondation de la « marxologie » scientifique à travers la création de l’Institut MarxEngels de Moscou en 1921. En présentant l’éditeur de la première MEGA tant comme un érudit marxiste respecté que comme un militant inflexible opposé à l’emprise de Staline sur le parti, l’article traite également des enjeux inhérents à toute recherche marxologique, comme la difficile articulation entre approche scientifique et impératif politique.
Du sens commun à son « noyau sain ». L’historicité du sens commun selon Gramsci
Authors: Rouquayrol Louis
Published: April 2023

Gramsci avance, dans ses Cahiers de prison , un certain nombre de propositions sur le sens commun. À partir d’elles, on peut penser une méthode qui permettrait de construire une histoire du sens commun et une histoire de la philosophie comme pratique de transformation du sens commun. Cinq thèses, en particulier, sont examinées : 1) tous les hommes sont philosophes ; 2) l’histoire de la philosophie livre une histoire déformée du sens commun ; 3) le sens commun est affecté de différents niveaux de profondeur historique ; 4) il existe un noyau sain du sens commun (le bon sens) ; 5) la transformation du sens commun engage un processus moléculaire par lequel un individu s’élève à la conscience critique de ses propres manières de penser, de sentir et d’agir.
Les témoins de la séparation, les cicatrices parlantes
Authors: Tonoyan Artur
Published: April 2023

L’auteur, psychologue et inscrit à l’Institut de psychanalyse de Paris, où il suit sa formation, s’est engagé comme psychologue volontaire pour soutenir les soldats arméniens engagés sur le champ de bataille dans le Caucase pendant la guerre déclenchée par la République d’Azerbaïdjan. Il développe ici le récit d’une psychothérapie avec un soldat blessé puis transféré dans le centre de réhabilitation mentale de l’armée arménienne à Dilijan. Il s’appuie sur la théorie que Freud a développée après la fin de la première guerre mondiale, avec Ferenczi et d’autres, considérant que le psychotraumatisme de guerre est en lien avec une situation douloureuse et traumatique déjà vécue pendant l’enfance. Il travaillera avec le soldat à propos de successions d’associations puis de rêves survenant par rapport à la cicatrice récente et une autre ancienne datant de ses deux ans.
En guise d’introduction
Authors: Fontaine Marion
Published: April 2023

Cet article présente le contenu des « Lectures » 2020 des Cahiers Jaurès .
Quid après les lois de Moore et de Koomey ?
Authors: Mazauric Vincent , Auffèves Alexia , Ezratty Olivier , Ciliberto Sergio
Published: April 2023

Pendant près de cinquante ans, les lois de Moore et de Koomey ont caractérisé les progrès continus des performances computationnelles des microprocesseurs, et accompagné – voire fondé – l’exceptionnelle croissance de l’industrie du semi-conducteur. Ainsi, les ordinateurs sont devenus de plus en plus petits et de moins en moins coûteux, tout en étant de plus en plus rapides et puissants, alimentant ainsi un perpétuel « effet rebond » du secteur des technologies de l’information et de la communication (TIC) qui n’est toujours pas arrivé à « satiété » ! Néanmoins, les fabricants de microprocesseurs se heurtent, depuis quelques années, aux limites physiques des hypothèses qui avaient permis de conjecturer la loi de Koomey. Si bien que l’avenir de l’industrie des semiconducteurs, et plus généralement du secteur des TIC, doit désormais se construire au-delà de la loi de Moore. Dans le même temps, la massification actuelle a conduit à identifier le secteur des TIC comme étant largement intensif en énergie électrique, et donc fortement émissif en CO 2 , mais aussi extractif en matériaux critiques, alors qu’il était perçu comme « immatériel » il y a encore quelques années de cela. Pour envisager le rôle que peuvent jouer les technologies de l’information et de la communication en tant que réponse aux enjeux du développement durable, il faut donc relativiser le concept de performance computationnelle et revenir au lien entre information et énergie, qui a été énoncé, y compris dans le contexte digital, bien avant la loi de Moore. Les lois de Moore et de Koomey n’apparaissent alors que comme des « sentiers » conjoncturels menant à la maturité thermodynamique, qui est mesurée par une tendance vers la réversibilité. Afin que le « data deluge » ne se transforme pas en « mur de l’énergie », d’autres paradigmes devront être envisagés pour accompagner les futurs défis à relever par un secteur des technologies de l’information et de la communication engagé sur la voie de la soutenabilité.
La place du numérique dans la transition énergétique
Authors: Guérassimoff Gilles
Published: April 2023

La transition énergétique est sur tous les fronts pour œuvrer à la limitation des effets du changement climatique. Le numérique est un candidat qui semble tout désigné pour contribuer à l’aboutissement de cette transition, vu l’adéquation entre l’urgence climatique et le dynamisme du développement du secteur. Pour tenter d’évaluer la place du numérique dans la transition énergétique, il est important de définir en premier lieu le périmètre de la notion de numérique. Ensuite, il est nécessaire de quantifier son impact énergétique pour évaluer les applications qui seront bénéfiques à cette transition. Enfin, il ne faut pas occulter les risques et les limites de son déploiement. Quelques exemples sont évoqués pour illustrer les domaines privilégiés de son application.
Le rôle de la flexibilité dans le système électrique d’aujourd’hui et de demain
Authors: Burtin Alain
Published: April 2023

L’électricité ne se stocke pas. Il faut la produire, la transporter et la distribuer quand on en a besoin. Il faut pour cela disposer de marges et de leviers de flexibilité afin d’assurer l’ajustement physique de l’offre et de la demande d’électricité à chaque instant, en respectant des critères prédéfinis de sécurité et de fiabilité des réseaux électriques. La décarbonation des mix électriques avec le développement massif des EnR modifie en profondeur les fondamentaux d’exploitation des systèmes électriques, dont les besoins de flexibilité augmentent pour pouvoir gérer la variabilité des EnR, tandis que les principales sources de flexibilité constituées par les centrales conventionnelles se réduisent. Dans cet article, nous abordons la montée des enjeux de flexibilité dans le système électrique d’aujourd’hui et les leviers actionnés pour y répondre, les adaptations nécessaires pour atteindre les objectifs européens à l’horizon 2030, ainsi que les perspectives post-2030.
Black soldier fly larvae (Hermetia illucens) as a meat replacer in a burger patty
Authors: Bessa L.W. , Pieterse E. , Marais J. , Hoffman L.C.
Published: April 2023

Black soldier fly larvae (BSFL) have shown potential as a functional and safe food ingredient. However, there are still limited studies demonstrating its application in food. The aim of this study was to determine whether BSFL could partially/fully replace beef in a burger patty. Five different treatments were investigated to determine which percentage of BSFL inclusion could compare to control beef patties in terms of nutrition, colour, pH, water activity, texture, and shelf-life stability (15-day, 4 °C). Treatments consisted of a beef patty (control) and four different BSFL treatments with partial/full replacement of beef with BSFL (25, 50, 75 and 100%). It was found that BSFL could not fully replace beef in a burger patty, as the 100% BSFL patty could not hold its structure upon forming or cooking. Partial replacement of beef with BSFL was found to be more successful, with only the raw 75% BSFL patties being significantly softer than the control (P<0.01). The control treatment was higher (P<0.01) in protein, fat (dry matter) and moisture than all the BSFL treatments. Texture profile analysis indicated that the treatments had little effect on hardness, gumminess, and springiness on the raw patties, however, the changes became evident upon cooking. While the BSFL patties had lower cooking losses than the control patty, they were darker in colour and had a softer texture (P<0.01). Overall, the 25% BSFL patty was the closest to the control patty, and further developments are recommended to improve the formulation to mimic a 100% beef patty more closely.
Aflatoxin in peanuts and maize: an overview on occurrence, regulations, prevention, and control methods
Authors: Ahmad M. , Han Z. , Kong Q.
Published: April 2023

Aflatoxins belong to a group of highly carcinogenic mycotoxins, produced mainly byAspergillus flavus andAspergillus parasiticus in various agricultural food commodities. It is hard to eliminate them from food and feed due to their high stability. Aflatoxin contamination in food grains, particularly peanut and maize, continues to cause significant health concerns in the population of developing nations. They can be fatal to humans and animals. Several actions can be taken to protect both humans and animals by following all applicable laws and regulations controlling aflatoxins, preventing pre- and post-harvest contamination, reducing the synthesis of aflatoxins, decontamination, and detoxification. This review will focus on the occurrence of aflatoxins, factors affecting aflatoxin production, worldwide regulations of aflatoxins, adverse effects on health and economy, prevention, and control strategies for aflatoxins, specifically in peanuts and corn, to assure food safety and security. This review is intended to be educational not just for health-conscious consumers but also for authorities in the field to pave the path for future research to address the gaps in knowledge about mycotoxins and food safety.
Fixed-time synchronization of nonlinear coupled memristive neural networks with time delays via sliding-mode control
Authors: Geng Xingting , Feng Jianwen , Zhao Yi , Li Na , Wang Jingyi
Published: April 2023

This article focuses on achieving fixed-time synchronization (FxTS) of nonlinear coupled memristive neural networks (NCMMN) with time delays. We propose a novel integrable sliding-mode manifold (SMM) and develop two control strategies (chattering or non-chattering) to achieve FxTS. By selecting appropriate parameters, some criteria are established to force the dynamics of NCMMN to reach the designed SMM within a fixed time and remain on it thereafter. Additionally, they provide estimations for the settling time (TST). the validity of our results is demonstrated through several numerical examples.
Onset of triple-diffusive convective stability in the presence of a heat source and temperature gradients: An exact method
Authors: Yellamma  , Manjunatha N. , Khan Umair , Elattar Samia , Eldin Sayed M. , Chohan Jasgurpreet Singh , Sumithra R. , Sarada K.
Published: April 2023

In the current work, in the presence of a heat source and temperature gradients, the onset of triple-diffusive convective stability is studied for a fluid, and a fluid-saturated porous layer confined vertically by adiabatic limits for the Darcy model is thoroughly analyzed. With consistent heat sources in both layers, this composite layer is subjected to three temperature profiles with Marangoni effects. The fluid-saturated porous region's lower boundary is a rigid surface, while the fluid region's upper boundary is a free surface. For the system of ordinary differential equations, the thermal surface-tension-driven (Marangoni) number, which also happens to be the Eigenvalue, is solved in closed form. The three different temperature profiles are investigated, the thermal surface-tension-driven (Marangoni) numbers are calculated analytically, and the effects of the heat source/sink are studied in terms of corrected internal Rayleigh numbers. Graphs are used to show how different parameters have an impact on the onset of triple-diffusive convection. The study's parameters have a greater influence on porous layer dominant composite layer systems than on fluid layer dominant composite layer systems. Finally, porous parameters and corrected internal Rayleigh numbers are stabilize the system, and solute1 Marangoni number and ratio of solute2 diffusivity to thermal diffusivity of fluid are destabilize the system.
On efficient numerical approaches for the study of the interactive dynamics of fractional eco-epidemiological models
Authors: George Reny , Rezapour Shahram , Alharthi Mohammed Shaaf , Aljohani A. F. , Günay B.
Published: April 2023

The present study aims to consider a mathematical eco-epidemiological model involving two fractional operators. To this end, we provide approximate solutions to these fractional systems through the application of a numerical technique that is based on the rule of product integration. This feature contributes greatly to the efficiency and effectiveness of both methods. We have also presented some theoretical discussions related to the equilibrium points of the system. Further, several numerical simulations are presented in order to illustrate the impact of choosing different parameters on the dynamics of the model. It is demonstrated that the obtained numerical results are completely consistent with the expected theoretical results. Moreover, both techniques can be used to solve other problems in epidemiology and describe other problems in the future. The article's model has never been studied via the employed fractional operators, and this is a distinct point for our work and other existing research.
Existence theory for a third-order ordinary differential equation with non-separated multi-point and nonlocal Stieltjes boundary conditions
Authors: Alsulami Mona
Published: April 2023

This study develops the existence of solutions for a nonlinear third-order ordinary differential equation with non-separated multi-point and nonlocal Riemann-Stieltjes boundary conditions. Standard tools of fixed point theorems are applied to prove the existence and uniqueness of results for the problem at hand. Further, we made use of the fixed point theorem due to Bohnenblust-Karlin to discuss the existence of solutions for the multi-valued case. Lastly, we clarify the reported results by means of examples.
L’expérience américaine. À propos de quelques Vierges romanes conservées aux États-Unis
Authors: Kargère Lucretia
Published: April 2023

Cet article présente le résultat d’observations techniques et d’analyses scientifiques de sculptures romanes en bois polychromé dans les collections de musées aux États-Unis. Une étude approfondie de la polychromie originale de quatre sculptures du Metropolitan Museum of Art de New York sert de point de départ pour une meilleure connaissance des matériaux utilisés et de leur mise en œuvre à cette époque. Seront principalement présentées : la Vierge en majesté provenant des environs d’Autun ; la Vierge en majesté d’Auvergne dite Vierge Guennol ; la Vierge en majesté connue sous le nom de Vierge Morgan ; la Vierge en majesté dite de Montvianeix. Le raffinement des techniques sur les quatre sculptures allant de l’application de simples couleurs monochromes à des superpositions plus complexes de couches opaques et translucides à base de protéine ou d’huile, en passant par l’addition d’éléments en verre ou en métal, démontre la sophistication des œuvres étudiées. D’intérêt certain est l’identification de reliefs en étain et d’un colorant rouge issu d’un insecte, le Kerria lacca (Kerr), que l’on commence juste à découvrir sur des œuvres du xiie siècle. De surcroît, le rapprochement stylistique souvent évoqué entre la Vierge de Montvianeix et celle dite Morgan est confirmé par l’observation de procédés de fabrication communs, dont certains se retrouvent sur la Vierge de Heume-l’Église en Auvergne.
La polychromie de la sculpture médiévale française, xiie-xve siècles. Bilan des examens et analyses entrepris au C2RMF
Authors: Le Hô Anne-Solenn , Pagès-Camagna Sandrine
Published: April 2023

Au cours des trente dernières années, les études sur la polychromie médiévale se sont multipliées, au point qu’aujourd’hui, au C2RMF, les analyses de polychromie se sont généralisées et qu’une étude est presque toujours concomitante à chaque restauration de sculptures polychromées. Les examens et les analyses ont apporté à ces études un éclairage scientifique majeur sur la nature des matériaux, leur usage et le rendu des couleurs. Le présent article propose d’appréhender la polychromie médiévale française, en approfondissant notre connaissance des techniques picturales et décoratives utilisées grâce au bilan des résultats obtenus au C2RMF sur plus d’une centaine de sculptures en pierre et bois.
La Vierge à l’Enfant, dite Notre-Dame de Bonnes-Nouvelles (Toulouse, musée des Augustins)
Authors: Faunières Dominique , Pagès-Camagna Sandrine , Riou Charlotte
Published: April 2023

Notre-Dame de Bonnes-Nouvelles, Vierge à l’Enfant du xive siècle conservée au musée des Augustins de Toulouse (RA 511), a retrouvé récemment des témoins importants de son exceptionnelle polychromie. Un décor peint, riche et complexe, a pu être ainsi redécouvert. Sur le manteau de la Vierge, un semis de paons, de branchages fleuris et de motifs floraux en accolade sur un fond blanc contraste avec les fleurs de lis dorées sur un fond bleu du revers. Le voile de la Vierge, qui enveloppe également l’Enfant, présente des aigles dorées et des fleurettes stylisées, là encore sur un fond blanc. Le rouge de la robe offrait une touche d’éclat supplémentaire à cet ensemble d’un raffinement extrême.
Digital Marketing in Cultural Heritage
Authors: Carignani Francesco , Clemente Laura , Iodice Gesualda , Bifulco Francesco
Published: April 2023

The contemporary cultural scenario is called upon to face challenges deriving from the intersection between social and technological variables, and to develop new strategic trajectories capable of stimulating the interest and involvement of a new audience of digital natives. If assisted with effective marketing strategies, metaverse and virtual platforms can become a fundamental strategic tool for cultural players to build a lasting and solid relationship with their reference stakeholders and with a new target audience. This chapter analyses the role that digital and immersive technologies can have in increasing participation and engagement of young adult customers.
Metaverse and Cultural Marketing in Hospitality and Tourism
Authors: Kumar Sanjeev , Dhiraj Ankit , Hassan Shuaibu Chiroma Chiroma
Published: April 2023

Metaverse is a thirty-year-old term, but a new formation. Metaverse is termed the 4th era of networking and computing – thereby succeeding mainframes (Ball, 2022). The Chapter will analyse the metaverse from two perspectives; it will look at the metaverse as a marketing tool and, or promote and sell goods and services in the hospitality industry; to use the metaverse as a marketing strategy in cultural marketing, and the future implications of metaverse on the hospitality industry as a whole. The global tourism and hospitality industry, currently, is experiencing some significant transformations due to certain disruptive innovations in the digital spheres across the globe – this includes the ‘metaverse'. Similarly, the notions of the ‘metaverse' as well as its virtual reality experiences have altered people's perspectives radically on the future of technology and its potential impacts on the tourism and hospitality industries.
Redefining Marketing Rules Through Smart Devices
Authors: Bathla Devesh , Bathla Raina , Gaikwad Dashrath , Kaur Navneet
Published: April 2023

In the 21st century, wearable innovation has purchased new advancements which has helped wearables to take off in the mechanical market. The Bluetooth headset, with the assistance of new Bluetooth innovation, was introduced in the year 2002 by Nokia. The headset permitted clients to get calls without utilizing their hands. This headset accomplished extraordinary prevalence in that time and still numerous clients are utilizing it. Further in 2007, sportswear brands like Nike and technology giants like Apple made a wellness following unit which is utilized to follow the development of the clients. With the assistance of shoe installed tracker, clients can see the ongoing, separation secured, calories burned, and speed expended through exercise on the Nano screen of iPod. While it is intended to study the awareness of Smart Wearables, it is also synthesized to identify the key perceptions about smart wearables in the study. It is further being analysed to check the influence of digital marketing in purchase decision for Smart wearables with specific focus on all digital platforms.
Growth in Agricultural Productivity
Authors: Sapolaite Vaida , Balezentis Tomas
Published: April 2023

This study examines agricultural total factor productivity (TFP) from theoretical and empirical perspectives. Specifically, the measures, relevant data, and major sources of the TFP growth are discussed. Using the sector-level growth and productivity data from the EU KLEMS, EUROSTAT, FAOSTAT, and USDA databases, the TFP growth in the EU countries over 1996–2019 is considered. The sources of the TFP growth are analyzed. The results suggest that agricultural TFP increased in almost all EU countries over the period covered. TFP growth appears as an important component of labour productivity and value-added growth in the EU agriculture. The differences among the databases considered are noted in the sense of input and output levels and TFP growth rates.
FLAIRR-Seq: A Method for Single-Molecule Resolution of Near Full-Length Antibody H Chain Repertoires
Authors: Ford Easton E , Tieri David , Rodriguez Oscar L , Francoeur Nancy J , Soto Juan , Kos Justin T , Peres Ayelet , Gibson William S , Silver Catherine A , Deikus Gintaras , Hudson Elizabeth , Woolley Cassandra R , Beckmann Noam , Charney Alexander , Mitchell Thomas C , Yaari Gur , Sebra Robert P , Watson Corey T , Smith Melissa L
Published: April 2023

Current Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) using short-read sequencing strategies resolve expressed Ab transcripts with limited resolution of the C region. In this article, we present the near-full-length AIRR-seq (FLAIRR-seq) method that uses targeted amplification by 5′ RACE, combined with single-molecule, real-time sequencing to generate highly accurate (99.99%) human Ab H chain transcripts. FLAIRR-seq was benchmarked by comparing H chain V (IGHV), D (IGHD), and J (IGHJ) gene usage, complementarity-determining region 3 length, and somatic hypermutation to matched datasets generated with standard 5′ RACE AIRR-seq using short-read sequencing and full-length isoform sequencing. Together, these data demonstrate robust FLAIRR-seq performance using RNA samples derived from PBMCs, purified B cells, and whole blood, which recapitulated results generated by commonly used methods, while additionally resolving H chain gene features not documented in IMGT at the time of submission. FLAIRR-seq data provide, for the first time, to our knowledge, simultaneous single-molecule characterization of IGHV, IGHD, IGHJ, and IGHC region genes and alleles, allele-resolved subisotype definition, and high-resolution identification of class switch recombination within a clonal lineage. In conjunction with genomic sequencing and genotyping of IGHC genes, FLAIRR-seq of the IgM and IgG repertoires from 10 individuals resulted in the identification of 32 unique IGHC alleles, 28 (87%) of which were previously uncharacterized. Together, these data demonstrate the capabilities of FLAIRR-seq to characterize IGHV, IGHD, IGHJ, and IGHC gene diversity for the most comprehensive view of bulk-expressed Ab repertoires to date.
Awareness and use of Maternal and Child Health-Care Services among People of Dagbadna Karu Local Government of Nasarawa State
Authors: Olorunfemi Olaolorunpo , Itula Maryjane
Published: April 2023

Background and Aim:

Maternal health care services are critical to reducing maternal fatalities and should be available throughout the health system due to their importance in ensuring safe motherhood and the overall well-being of families and communities. The purpose of this research is to ascertain the level of Maternal and Child Health (MCH) awareness and utilization among residents of Nasarrawa State’s Dagbadna Karu Local Government Area.

Materials and Methods:

Purposive sampling was used to determine the sample size (n = 286) for a descriptive cross-sectional study that ran from September 2022 to December 2022. Statistical Package Service Software (SPSS) version 23.0 was used to analyze the data, which included tables, percentages, and Chi-square test statistics at the 0.05 level of significance.

Results:

With a mean age of 29.6 years, 42% of the participants were between the ages of 33 and 38. In comparison, 255 of the participants (89.5%) were married, while 14 (4.9%) were unmarried. The most common level of education is secondary education, which is held by 111 respondents, or 38.8%. This study found a high level of awareness (196.6, 68.7%) but a low level of utilization of MCH Care Services (137.5, 48.1%). It also demonstrates that participants’ knowledge and utilization of maternal and child healthcare services are not significantly related (Chi-square (χ2)= 8.867, df = 1, P = 0.012).

Conclusions:

The primary goal of MCH Services remains to ensure that every woman maintains optimal health throughout pregnancy and puerperium, with a healthy mother and baby at the end of pregnancy, and to support the child’s health throughout infancy and childhood. As a result, this research suggests a strategy for increasing community participation and, ultimately, sustaining and improving the quality, usability, and accessibility of maternal health care services provided by government agencies in both rural and urban areas.
Efficacy Outcomes of Tenecteplase versus Alteplase in Patients with Ischemic Stroke in Therapeutic Window: Experience from a Single Institution
Authors: Chandra Amit , Raina Adnan Firdous , Wani Maqbool , Ganie Hilal , Dar Waseem , Yaqoob Arjimand , Asimi Ravouf
Published: April 2023

Background and Aim:

The World Health Organization estimated that 15 million people throughout the world suffer stroke every year. Only 5%–10% of all acute ischemic stroke (AIS) patients presenting to emergency departments (EDs) are eligible for and receive thrombolytic therapy. This study was conducted to assess and compare the efficacy and safety profile of thrombolysis with tenecteplase (TNK) with that of alteplase among patients with AIS who were eligible for thrombolysis.

Materials and Methods:

This was a hospital-based prospective observational study. All the patients who presented with AIS within the time window period of ≤4.5 h to ED of Sher-i-Kashmir Institute of Medical Sciences, Soura, from September 2018 to March 2021, were screened for eligibility of thrombolysis by TNK. A total of 76 patients were enrolled; among which 42 were thrombolysed with TNK and 34 patients were thrombolysed with alteplase. These data were compared with departmental data of patients thrombolysed by alteplase during July 2015–July 2017. Inclusion and exclusion criteria used in the study were as per the American Heart Association/American Stroke Association guidelines for thrombolysis. Efficacy and safety were assessed and compared of the two drugs.

Results:

After 24 h of thrombolysis, early neurological improvement occurred in 62% of TNK patients compared to only 35% of patients from alteplase group, which was significant statistically (P < 0.05). An excellent functional outcome, defined as the Modified Rankin Scale (mRS) of 0–1 at 3 months of discharge, was seen in 67.6% of TNK and 48.5% of alteplase group. A poor recovery, defined as the mRS of 4–6 at 3 months of follow-up, was seen in 16% and 21% in TNK and alteplase group patients, respectively.

Conclusion:

TNK appears to be characterized by a better safety and efficacy profile than alteplase; however, further multicenter studies and randomized controlled trials are required to confirm our preliminary findings.
The effect of dexmedetomidine on wake-up test quality when muscle relaxants are not used: A randomized control trial
Authors: Sultan Wesameldin A. , Afify Noha A.
Published: April 2023

Background and Aims:

Stagnara wake-up test is a simple reproducible neuromonitoring method during spinal surgery which replaces the evoked potential monitoring in the absence of neuromonitoring facilities. Dexmedetomidine (DEX) effect on the intraoperative wake-up test is still unclear. The present study was conducted to evaluate the effectiveness of DEX on the quality of wake-up test during spinal correction surgery.

Methods:

A randomized controlled study was carried out over 62 patients randomized into two equal groups planned for elective minimally invasive corrective spine surgery. Instead of atracurium administration in the control group, patients in the experimental group were administered titrated continuous intravenous infusion of DEX at a dose of 0.2–0.7 μg/kg/hour. Lidocaine 2% spray around the vocal cords was done in both the groups to facilitate toleration of the endotracheal tube.

Results:

The DEX group showed statistically significant longer duration and better quality of the wake-up test. Statistically significant better haemodynamic state, a lower amount of intraoperative sedatives and higher amount of intraoperative analgesics were also evident in the DEX group. The postoperative Ramsay sedation scale was significantly lower in the DEX group just after extubation.

Conclusion:

The DEX use has shown an improving effect on the wake-up test quality, with slightly prolonged wake-up time. The present work supports the use of DEX as an adjuvant drug alleviating the need for the neuromuscular blockade, inducing a better haemodynamic profile, exhibiting better sedation and improving the awakening condition.
Comparison of continuous erector spinae plane block and thoracic paravertebral block for postoperative analgaesia in patients undergoing modified radical mastectomy: A randomised controlled non-inferiority trial
Authors: Sharma Lovepriya , Bhatia Pradeep , Mohammed Sadik , Sethi Priyanka , Chhabra Swati , Kumar Mritunjay
Published: April 2023

Background and Aims:

Modified radical mastectomy (MRM) is associated with significant postoperative pain for which many blocks including thoracic paravertebral (TPV) block are being used. Erector spinae plane (ESP) block is a recently described technique. We planned to compare the efficacy and safety of ultrasound-guided continuous ESP and TPV blocks for postoperative analgaesia following MRM.

Methods:

Sixty-six patients belonging to American Society of Anaesthesiologists physical status I and II, aged 25–85 years, undergoing MRM were enrolled and randomly allocated into two groups. Ipsilateral block was given preoperatively at T3 or T4 level with 20 ml of 0.5% ropivacaine and 50 μg fentanyl. Infusion of 0.5% and 0.2% ropivacaine with fentanyl 2 μg/ml at a rate of 5 ml/hr was continued during intraoperative and postoperative period, respectively. Pain was assessed using visual analogue scale (VAS) till 24 hours. Block performance time, time to first rescue analgaesia, total amount of rescue analgaesic consumed, the incidence of procedure-related and postoperative complications, failure rate and patient satisfaction score were also recorded. Data collected were analysed using the Chi-square test or Student’s t-test with the help of SPSS 22.0.

Results:

Demographics, baseline vitals, VAS scores both at rest and on movement, block performance time, time to first rescue analgaesia, the total amount of rescue analgaesia and patient satisfaction score were comparable in both groups (P value > 0.05). No complications were observed in either group.

Conclusion:

In patients undergoing MRM, continuous catheter technique ESP block is as efficacious and safe as TPV block for providing prolonged postoperative analgaesia.
Neck Circumference is Associated with General and Central Obesity in Young Indian Adults
Authors: Raju Aruna , Santhanakrishnan Niveatha , Sathiyaseelan Manikandan
Published: April 2023

Background:

Obesity has been a major concern due to its increasing prevalence and associated metabolic complications. Body mass index (BMI) assesses general obesity, but it does not distinguish between muscle and fat accumulations, so using only BMI can lead to an erroneous result. Waist circumference (WC), a marker of central obesity, predicted mortality risk better than BMI. However, WC can be affected by abdominal distension, is time-consuming, and may not be culture-sensitive. Neck circumference (NC) is devoid of these disadvantages and is believed to be an index of upper body fat distribution. This study aimed to assess the association of neck circumference with general and central obesity and to identify the cut-off points for evaluating obesity in young adults using NC.

Material and Methods:

Height, weight, waist, and hip circumference were measured to determine BMI and waist-hip ratio. NC was measured at the level of the mid-cervical spine and mid-anterior neck in a standing position with the arms hanging freely. For males with a laryngeal prominence, NC was measured just below the prominence.

Results:

In total, 357 (170 male and 187 female) young, healthy Indian adults aged 18–25 participated. Neck circumference (NC) is significantly associated with BMI and WC in both genders. We found the best cut-off for male and female participants to be ≥34 cm and ≥30.5 cm, with a sensitivity of 88.3% and 84.4% for assessing obesity.

Conclusion:

NC may be a better alternative to BMI and WC as a marker to assess obesity since it is more practical, simple, inexpensive, time-saving, and less invasive.
The Role of Travel Time on Hospital Utilization in the Islands Area: A Cross-Sectional Study in the Maluku Region, Indonesia, in 2018
Authors: Ipa Mara , Laksono Agung Dwi , Wulandari Ratna Dwi
Published: April 2023

Background:

Maluku region is one of the vulnerable areas in Indonesia, and this region has extreme geographical conditions with thousands of islands. The study aims to analyze the role of travel time to a hospital in the Maluku region in Indonesia.

Material and Methods:

This cross-sectional study analyzed the 2018 Indonesian Basic Health Survey data. The research included 14,625 respondents by stratification and multistage random sampling. The study used hospital utilization as an outcome variable and the travel time to the hospital as an exposure variable. Moreover, the study employed nine control variables: province, residence, age, gender, marital status, education, employment, wealth, and health insurance. The study performed binary logistic regression to interpret the data in the final analysis.

Results:

The result shows a relationship between travel time and hospital utilization. Someone with a travel time of 30 min or less to the hospital has a 1.792 (95% CI 1.756–1.828) higher probability than those with a travel time of more than 30 min. The results of this analysis find that shorter travel time to the hospital has a better possibility of hospital utilization. In addition, the study also found eight control variables to have a significant relationship with hospital utilization.

Conclusion:

Shorter travel time to the hospital is more likely to be utilized in the Maluku region.
Social Support Status of the Elderly Population in Selected Villages in a Central India District
Authors: Khandre Ruchita R. , Raut Abhishek , Mundra Anuj
Published: April 2023

Background:

Social support has been considered an important social determinant of health because it assists individuals in reaching their physical and emotional needs. The current study was proposed to assess the social support status of the elderly in rural central India.

Material and Methods:

This observational cross-sectional study was conducted in selected four villages in central India on 460 elderly individuals for 5 months (Aug-Dec 2021) with the use of the MSPSS (Multi-dimensional Scale Perceived Social Support) questionnaire. Univariate analysis and multivariate analysis were carried out using R software.

Result:

Out of 460, 37 (8.04%) of the elderly were found to have low, 177 (38.47%) were moderate, and 246 (53.48%) were having high social support. The result showed age and education of the elderly were significantly associated with social support.

Conclusion:

Intergenerational activities, provision and strengthening of social platforms, and the addition social support components with comprehensive geriatric assessment can improve the current status.