bluuebunny/crossref_metadata_2025 huggingface dataset:
New Pseudomonas Bacterial Strains: Biological Activity and Characteristic Properties of Metabolites
Authors: Sidorova Tatiana M. , Tomashevich Natalia S. , Allahverdyan Valeria V. , Tupertsev Boris S. , Kostyukevich Yuri I. , Asaturova Anzhela M.
Published: July 2023

This paper investigates the antagonistic and plant growth promotion activity of the new indigenous bacteria antagonist strains P. chlororaphis BZR 245-F and Pseudomonas sp. BZR 523-2. It was found that on the 10th day of cultivation, BZR 245-F and BZR 523-2 exhibit an antagonistic activity against F. graminearum at the level of 59.6% and 15.1% and against F. oxysporum var. orthoceras at the level of 50.2% and 8.9%, respectively. Furthermore, the BZR 523-2 strain stimulated the growth of winter wheat seedlings more actively than the BZR 245-F strain. When processing seeds of winter wheat, Pseudomonas sp. BZR 523-2 indicators were higher than in the control: plant height increased by 10.3%, and root length increased by 18.6%. The complex characteristic properties of the metabolite were studied by bioautography and HPLC-MS. Bioautography proved the antifungal activity of phenazine nature compounds synthesized by the new bacterial strains. We qualitatively and quantitatively analyzed them by HPLC-MS analysis of the strain sample metabolites. In the BZR 245-F sample, we found more phenazine compounds of various types. Their total phenazine concentration in the BZR 245-F was more than five times greater than in the BZR 523-2. We defined crucial differences in the quantitative content of the other metabolites. Despite the difference between new indigenous bacteria antagonist strains, they can be used as producers of effective biopesticides for sustainable agriculture management.
Fluorescent Nanoparticle Uptake by Myzocytosis and Endocytosis in Colpodella sp. ATCC 50594
Authors: Sam-Yellowe Tobili Y. , Asraf Mary M. , Peterson John W. , Fujioka Hisashi
Published: July 2023

Colpodella sp. (ATCC 50594) is a free-living biflagellate predator closely related to pathogenic Apicomplexa such as Plasmodium, Cryptosporidium and Toxoplasma gondii. Colpodella sp. (ATCC 50594) obtain nutrients by preying on Parabodo caudatus using myzocytosis. The organization of the myzocytic apparatus and the mechanism of nutrient uptake into the posterior food vacuole of Colpodella species is unknown. In this study, we investigated myzocytosis using light and transmission electron microscopy. We investigated the uptake of 40 nm and 100 nm fluorescent nanoparticles and E. coli BioParticles by Colpodella sp. (ATCC 50594) in a diprotist culture. Transmission electron microscopy was used to investigate the morphology of the tubular tether formed during myzocytosis. E. coli BioParticles were taken up by P. caudatus but not by Colpodella sp. (ATCC 50594). Both protists took up the 100 nm and 40 nm beads, which were observed distributed in the cytoplasm of free unattached Colpodella sp. (ATCC 50594) trophozoites, and also in feeding Colpodella sp. (ATCC 50594) trophozoites and in the pre-cysts. Fragments of the nucleus and kinetoplast of P. caudatus and the nanoparticles were identified in the tubular tether being aspirated into the posterior food vacuole of Colpodella sp. (ATCC 50594). Unattached Colpodella sp. (ATCC 50594) endocytose nutrients from the culture medium independently from myzocytosis. The mechanisms of myzocytosis and endocytosis among Colpodella species may provide important insights into nutrient uptake among the pathogenic apicomplexans.
Status of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review
Authors: Eyang-Assengone Elsa-Rush , Makouloutou-Nzassi Patrice , Mbou-Boutambe Clark , Bangueboussa Félicien , Atsame Julienne , Boundenga Larson
Published: July 2023

Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to provide the scientific community with a summary document showing the mapping of this disease in Gabon. The articles dealing with onchocerciasis, animal reservoirs, surveillance, and elimination were analyzed. Results showed that little research has been performed. Most studies are concentrated in one region (The area of Lastourville). In addition, we observed that the distribution of the disease varies significantly across the country. Indeed, specific environments present a hyper-endemicity of the disease, while others are meso and hypo-endemic. So, we found some departments with a prevalence ranging from 0% to over 20%; within them, villages had infection levels comprising 10% to 60%, indicating potential hotspots. Vectors activities were studied in some areas. This paper showed the challenges encountered in the country to eliminate this disease. One solution is a deeper understanding of the disease’s bioecology to establish effective health policies to eliminate onchocerciasis in Gabon effectively.
Mapping the Spectral and Mineralogical Variability of Lunar Breccia Meteorite NWA 13859 by VNIR Reflectance Spectroscopy
Authors: Bruschini Enrico , Carli Cristian , Tosi Federico
Published: July 2023

We provide the first visible near-infrared (VNIR) reflectance spectroscopy characterization of a sample from the lunar feldspathic breccia NWA 13859. The sample is a 2 mm thick slab with an approximate area of 35 ± 2 cm2. We characterized the spectroscopic variability by choosing and analyzing representative spots throughout the sample. Our results show a distinct spectral contribution from orthopyroxene, which, according to a preliminary mineralogical characterization, should be a minor phase in the sample. In a second step, we measured several spectra along a transect between a clast and the matrix. In order to oversample the signal, the points analyzed along the sample were partly superimposed to each other (80% areal superposition). The same approach was extended to a grid of points covering an area of about 8.6 cm2, with the goal of obtaining a spatial resolution of the spectral parameters higher than the instrument’s spot size. Using this strategy, we obtained 2D maps of spectral parameters, which allowed us to infer the major mineralogical composition of the sample.
Magnetite Talks: Testing Machine Learning Models to Untangle Ore Deposit Classification—A Case Study in the Ossa-Morena Zone (Portugal, SW Iberia)
Authors: Nogueira Pedro , Maia Miguel
Published: July 2023

A comprehensive investigation into the application of machine learning algorithms for accurately classifying mineral deposit types is presented. The study specifically focuses on iron deposits in the Portuguese Ossa-Morena Zone, employing a limited dataset of trace element geochemistry from magnetites. The research aims to derive meaningful methodological and metallogenic conclusions from the obtained results. The findings demonstrate that the combination of a restricted dataset of trace element geochemistry from magnetites with diverse machine learning models serves as a reliable tool for achieving precise classifications of mineral deposit types. Among the machine learning methods evaluated, random forest, naïve Bayes, and multinomial logistic regression emerge as the most accurate classifiers, whereas the support vector machine, the k-nearest neighbour, and artificial neural networks exhibit lower performance scores. By integrating all literature-proposed classifications, and applying them to selected iron deposits, confident classifications were obtained. Alvito and Azenhas are reliably classified as skarns, whereas Monges, Serrinha, and Vale da Arca are classified as either porphyry or a Banded Iron Formation (BIF). Notably, the classification of Orada proves cryptic, encompassing both BIF and volcanogenic massive sulphide (VMS) deposit types. Moreover, the application of machine learning models to pertinent case studies offers valuable insights not only for classifying mineral deposit types but also for discerning mixed or complex origins. This approach provides meaningful results that can aid in the interpretation of mineral deposit types and may facilitate the identification of new mineral exploration targets. The research highlights the robustness of machine learning algorithms in interpreting magnetite data and underscores their potential significance in exploration projects.
Effect of Karst Geomorphology on the Sedimentary Mineralization and Geochemical Distribution of Bauxite: An Example from the Xiaoyuan Area in Qingzhen, Guizhou Province
Authors: Mo Hongcheng , Yang Ruidong , Luo Chaokun , Li Xinzheng , Ji Yanbing , Yang Guiyuan , Zhou Xumei , Gao Chuanqian , Hu Xu , Zeng Zhimeng
Published: July 2023

Bauxite, in central Guizhou, is predominantly karst bauxite, but there is insufficient research on the effect of karst paleogeomorphology on bauxite development. Xiaoyuan bauxite is also a karst bauxite, and high- and low-iron bauxite deposits exist in the study area. This study conducts geological modeling of karst bauxite using controlled-source audio-frequency magnetotelluric (CSAMT) data and drill core data. The effects of karst paleogeomorphology on bauxite deposition and mineralization are evaluated by assessing karst paleogeomorphology, conducting a mineralogical analysis of drill cores at different locations, and determining the geochemical distribution characteristics of the elements in the horizontal and vertical directions. Combined with previous research results, we propose two metallogenic processes of high-iron and low-iron bauxite. The findings are significant for understanding the mechanism of bauxite formation.
Coupling Relationships between Sedimentary Microfacies, Sand Bodies, and Tectonic Fracture Characteristics in Braided River Deltas: A Case Study of the Bashijiqike Formation in the Keshen 2 Area
Authors: Wang Zhuangsheng , Lin Xiaobing , Zhu Songbai , Fan Junming , Zheng Yuchao
Published: July 2023

Fractures are crucial as main natural gas transport channels in tight sandstone reservoirs. In order to reveal the correlation between the combination of fractures in Block Keshen 2 and sandstone, we have collected drilling core data, logging curve data, imaging logging data, and rock thin-section data from the Bashjiqike Formation in the Keshen 2 area, and by classifying and statistically analyzing the different influencing factors of fractures, we have established a correlation between the development of fractures and sandstone thickness, lithology, and sedimentary microfacies. The results reveal the following: (1) frequent vertical superposition and lateral migration occur in the sedimentary sand bodies of the Bashijiqike Formation. Three types of patterns of sand bodies have been identified according to the changes in microfacies. Type I refers to the patterns of sand bodies developed in main subaqueous distributary channels, type II refers to the patterns of sand bodies developed in secondary subaqueous distributary channels or mouth bars, and type III refers to the patterns of sand bodies developed in isolated subaqueous distributary channels; (2) three types of fracture patterns have been described in the various sand bodies of the Bashijiqike Formation in the Keshen area, including high–medium-angle branch-like fracture patterns, medium-angle reticular fracture patterns, and isolated fractures; (3) the coupling relationship among sedimentary microfacies, sand body patterns, and fracture patterns has been established. The high–medium-angle branch-like fracture patterns mainly develop in the main underwater distributary channel and the type I sand body patterns. The medium-angle reticular fracture patterns mainly develop in the secondary underwater distributary channel and mouth bars, as well as the type II sand body patterns. Isolated fractures can occur in all sedimentary microfacies but are sporadically distributed within the three types of sand body patterns. The research results present the regularity of fracture development in fractured reservoirs, which can be applied to oil and gas fields with the same background, providing certain geological evidence for exploration and development.
Revalorisation of Fine Recycled Concrete in Acid Mine Water Treatment: A Challenge to a Circular Economy
Authors: Barba-Brioso Cinta , Martín Domingo , Romero-Baena Antonio , Campos Paloma , Delgado Joaquín
Published: July 2023

Currently, only 50% of concrete produced from construction and demolition waste is being recycled in Europe. This falls short of the European Union’s target of 70% by 2020. Moreover, this figure only considers coarse fractions (>4 mm), as technical issues arise when using fine fractions. In pursuit of a complete circular life for recycled concrete, this investigation explores the potential use of fine fractions to enhance the physicochemical conditions and reduce the element concentration of acid mine drainage. Two trickling sets were prepared using a filter holder, with acidic waters passing through a layer of recycled concrete aggregates. Results revealed an immediate increase in water pH to neutral levels, a reduction in solution oxidation, and the complete, or near-complete retention, of potentially toxic elements by the substrate (with retention percentages of over 99.9% for Al and Fe, between 43.1% and 61.1% for S, over 91.1% for Zn, and over 99.1% for Cu). The experiment also showed a significant increase in Ca levels (tripling the initial value) and some Mg in the water, which could promote the subsequent precipitation of carbonates and the retention of trace metals. In summary, this study demonstrates the effectiveness of using recycled concrete aggregates in a laboratory setting. Further investigation is necessary to evaluate the feasibility of implementing this technique at the pilot scale.
Analysis of Dielectric Parameters of Fe2O3-Doped Polyvinylidene Fluoride/Poly(methyl methacrylate) Blend Composites
Authors: Bafna Minal , Deeba Farah , Gupta Ankit K. , Shrivastava Kriti , Kulshrestha Vaibhav , Jain Ankur
Published: July 2023

In this paper, we report the effect of metal oxide (Fe2O3) loading in different weight ratios (0.5%, 1%, 2%, and 4%) on the structural and electrical parameters, viz., the complex dielectric constant, electric modulus spectra, and the AC conductivity, of polymeric composites of PVDF/PMMA (30/70 weight ratio) blend. The structural and geometric measurements have been analyzed with the help of peak location, peak intensity, and peak shape obtained from XRD as well as from FTIR spectra. The electrical properties have been investigated using an impedance analyzer in the frequency range 100 Hz to 1 MHz. The real parts of the complex permittivity and the dielectric loss tangent of these materials are found to be frequency independent in the range from 20 KHz to 1 MHz, but they increase with the increase in the concentration of nano-Fe2O3. The conductivity also increases with an increased loading of Fe2O3 in PVDF/PMMA polymer blends. The electric modulus spectra were used to analyze the relaxation processes associated with the Maxwell–Wagner–Sillars mechanism and chain segmental motion in the polymer mix.
Rational Design and Multicomponent Synthesis of Lipid–Peptoid Nanocomposites towards a Customized Drug Delivery System Assembly
Authors: Rosalba Thaissa Pasquali F. , Matos Guilherme D. R. , Salvador Carlos Eduardo M. , Andrade Carlos Kleber Z.
Published: July 2023

Nanotechnology has assumed a significant role over the last decade in the development of various technologies applied to health sciences. This becomes even more evident with its application in controlled drug delivery systems. In this context, peptoids are a promising class of compounds for application as nanocarriers in drug delivery systems. These compounds can be obtained efficiently and with highly functionalized structural diversity via the Ugi 4-component reaction (U-4CR). Herein, we report the design of the process control strategy for the future development of lipid–peptoid-based customized drug delivery system assemblies. Over 20 lipid–peptoid nanocomposites were synthesized via the U-4CR in good to excellent yields. These products were successfully submitted to the nanoparticle formation by the emulsification–evaporation process from lipophilic solution and analyzed via Dynamic Light Scattering (DLS). Several molecules generated nanoparticles with a size ≤200 nm, making them good candidates for drug delivery systems, such as in cancer treatment.
Improved Viability of Probiotics via Microencapsulation in Whey-Protein-Isolate-Octenyl-Succinic-Anhydride-Starch-Complex Coacervates
Authors: Liu Qingqing , Lin Chutian , Yang Xue , Wang Shuwen , Yang Yunting , Liu Yanting , Xiong Mingming , Xie Yisha , Bao Qingbin , Yuan Yongjun
Published: July 2023

The aim of this study was to microencapsulate probiotic bacteria (Lactobacillus acidophilus 11073) using whey-protein-isolate (WPI)–octenyl-succinic-anhydride-starch (OSA-starch)-complex coacervates and to investigate the effects on probiotic bacterial viability during spray drying, simulated gastrointestinal digestion, thermal treatment and long-term storage. The optimum mixing ratio and pH for the preparation of WPI-OSA-starch-complex coacervates were determined to be 2:1 and 4.0, respectively. The combination of WPI and OSA starch under these conditions produced microcapsules with smoother surfaces and more compact structures than WPI-OSA starch alone, due to the electrostatic attraction between WPI and OSA starch. As a result, WPI-OSA-starch microcapsules showed significantly (p < 0.05) higher viability (95.94 ± 1.64%) after spray drying and significantly (p < 0.05) better protection during simulated gastrointestinal digestion, heating (65 °C/30 min and 75 °C/10 min) and storage (4/25 °C for 12 weeks) than WPI-OSA-starch microcapsules. These results demonstrated that WPI-OSA-starch-complex coacervates have excellent potential as a novel wall material for probiotic microencapsulation.
Synthesis and Characterization of Bulky Substituted Hemihexaphyrazines Bearing 2,6-Diisopropylphenoxy Groups
Authors: Ivanov Evgenii N. , Almeida-Marrero Verónica , Koifman Oskar I. , Aleksandriiskii Viktor V. , Torres Tomas , Islyaikin Mikhail K.
Published: July 2023

New substituted [30]trithiadodecaazahexaphyrines (hemihexaphyrazines) were synthesized by a crossover condensation of 2,5-diamino-1,3,4-thiadiazole with 4-chloro-5-(2,6-diisopropylphenoxy)- or 4,5-bis-(2,6-diisopropylphenoxy)phthalonitriles. The compounds were characterized by 1H-, 13C-NMR, including COSY, HMBC, and HSQC spectroscopy, MALDI TOF spectrometry, elemental analysis, IR and UV-Vis absorbance and fluorescence techniques.
LCMS/MS Phytochemical Profiling, Molecular, Pathological, and Immune-Histochemical Studies on the Anticancer Properties of Annona muricata
Authors: Abdallah Rehab H. , Al-Saleem Muneera S. M. , Abdel-Mageed Wael M. , Al-Attar Al-Sayed R. , Shehata Youssef M. , Abdel-Fattah Doaa M. , Atta Rahnaa M.
Published: July 2023

Annona muricate is a tropical plant that is well-known for its edible fruit of therapeutic interest. LCMS/MS analyses were applied to identify phytoconstituents of the ethanolic extract of the whole fruits and the aqueous extract of the edible fruit part, in addition to the investigation of their anticancer properties against Ehrlich ascites carcinoma (EAC) in male albino mice. LCMS/MS analyses resulted in the identification of 388 components, representing a wide array of classes of compounds, including acetogenins as the major constituents, alkaloids, flavonoids, and phenolics. Among them, four compounds were tentatively characterized as new compounds (1–4), including an acid derivative, protocatechuic-coumaroyl-quinic acid (1), and three flavonoid derivatives, dihydromyricetin galloyl hexoside (2), apigenin gallate (3), and dihydromyricetin hexouronic acid hexoside (4). Induction with EAC cells resulted in abnormalities in the gene expression of pro-apoptotic genes (Bax and caspase-3) and anti-apoptotic gene (Bcl-2) in the tumor mass. Moreover, microscopic, histopathological, and immune-histochemical examinations of the tumor mass and liver tissues exhibited extensive growth of malignant Ehrlich carcinoma cells and marked hydropic degeneration of hepatocytes and infiltration by tumor cells to liver tissue with marked inflammatory reaction. These abnormalities were markedly ameliorated aftertreatment of EAC mice with A. muricata extracts.
Untargeted Metabolomics Approach Using UHPLC-HRMS to Unravel the Impact of Fermentation on Color and Phenolic Composition of Rosé Wines
Authors: Leborgne Cécile , Meudec Emmanuelle , Sommerer Nicolas , Masson Gilles , Mouret Jean-Roch , Cheynier Véronique
Published: July 2023

Color is a major quality trait of rosé wines due to their packaging in clear glass bottles. This color is due to the presence of phenolic pigments extracted from grapes to wines and products of reactions taking place during the wine-making process. This study focuses on changes occurring during the alcoholic fermentation of Syrah, Grenache and Cinsault musts, which were conducted at laboratory (250 mL) and pilot (100 L) scales. The color and phenolic composition of the musts and wines were analyzed using UV-visible spectrophotometry, and metabolomics fingerprints were acquired by ultra-high performance liquid chromatography−high-resolution mass spectrometry. Untargeted metabolomics data highlighted markers of fermentation stage (must or wine) and markers related to the grape variety (e.g., anthocyanins in Syrah, hydroxycinnamates and tryptophan derivatives in Grenache, norisoprenoids released during fermentation in Cinsault). Cinsault wines contained higher molecular weight compounds possibly resulting from the oxidation of phenolics, which may contribute to their high absorbance values.
Germinated Rice Seeds Improved Resveratrol Production to Suppress Adipogenic and Inflammatory Molecules in 3T3-L1 Adipocytes
Authors: Monmai Chaiwat , Kim Jin-Suk , Baek So-Hyeon
Published: July 2023

Obesity is a major risk factor for a variety of diseases and contributes to chronic inflammation. Resveratrol is a naturally occurring antioxidant that can reduce adipogenesis. In this study, the antiadipogenic and anti-inflammatory activities of resveratrol-enriched rice were investigated in 3T3-L1 adipocyte cells. Cotreatment of dexamethasone and isobutylmethylxanthin upregulated adipogenic transcription factors and signaling pathways. Subsequent treatment of adipocytes with rice seed extracts suppressed the differentiation of 3T3-L1 by downregulating adipogenic transcription factors (peroxisome proliferator-activated receptor γ and CCAAT/enhancer-binding protein α) and signaling pathways (extracellular signal-regulated kinase 1/2 and protein kinase B Akt), this was especially observed in cells treated with germinated resveratrol-enriched rice seed extract (DJ526_5). DJ526_5 treatment also markedly reduced lipid accumulation in the cells and expression of adipogenic genes. Lipopolysaccharide (LPS)-induced inflammatory cytokines (prostaglandin-endoperoxide synthase 2 (COX-2), tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6) decreased in cells treated with DJ526_5. Collectively, DJ526_5 exerts antiadipogenic effects by suppressing the expression of adipogenesis transcription factors. Moreover, DJ526_5 ameliorates anti-inflammatory effects in 3T3-L1 adipocytes by inhibiting the activation of phosphorylation NF-κB p65 and ERK ½ (MAPK). These results highlight the potential of resveratrol-enriched rice as an alternative obesity-reducing and anti-inflammatory agent.
N-Doped Porous Carbon-Nanofiber-Supported Fe3C/Fe2O3 Nanoparticles as Anode for High-Performance Supercapacitors
Authors: Li Li , Xie Fengting , Wu Heyu , Zhu Yuanyuan , Zhang Pinghua , Li Yanjiang , Li Hengzheng , Zhao Litao , Zhu Guang
Published: July 2023

Exploring anode materials with an excellent electrochemical performance is of great significance for supercapacitor applications. In this work, a N-doped-carbon-nanofiber (NCNF)-supported Fe3C/Fe2O3 nanoparticle (NCFCO) composite was synthesized via the facile carbonizing and subsequent annealing of electrospinning nanofibers containing an Fe source. In the hybrid structure, the porous carbon nanofibers used as a substrate could provide fast electron and ion transport for the Faradic reactions of Fe3C/Fe2O3 during charge–discharge cycling. The as-obtained NCFCO yields a high specific capacitance of 590.1 F g−1 at 2 A g−1, superior to that of NCNF-supported Fe3C nanoparticles (NCFC, 261.7 F g−1), and NCNFs/Fe2O3 (NCFO, 398.3 F g−1). The asymmetric supercapacitor, which was assembled using the NCFCO anode and activated carbon cathode, delivered a large energy density of 14.2 Wh kg−1 at 800 W kg−1. Additionally, it demonstrated an impressive capacitance retention of 96.7%, even after 10,000 cycles. The superior electrochemical performance can be ascribed to the synergistic contributions of NCNF and Fe3C/Fe2O3.
Profiling the Antidiabetic Potential of Compounds Identified from Fractionated Extracts of Entada africana toward Glucokinase Stimulation: Computational Insight
Authors: Onikanni Sunday Amos , Lawal Bashir , Munyembaraga Valens , Bakare Oluwafemi Shittu , Taher Muhammad , Khotib Junaidi , Susanti Deny , Oyinloye Babatunji Emmanuel , Noriega Lloyd , Famuti Ayodeji , Fadaka Adewale Oluwaseun , Ajiboye Basiru Olaitan
Published: July 2023

Glucokinase plays an important role in regulating the blood glucose level and serves as an essential therapeutic target in type 2 diabetes management. Entada africana is a medicinal plant and highly rich source of bioactive ligands with the potency to develop new target drugs for glucokinase such as diabetes and obesity. Therefore, the study explored a computational approach to predict identified compounds from Entada africana following its intermolecular interactions with the allosteric binding site of the enzymes. We retrieved the three-dimensional (3D) crystal structure of glucokinase (PDB ID: 4L3Q) from the online protein data bank and prepared it using the Maestro 13.5, Schrödinger Suite 2022-3. The compounds identified were subjected to ADME, docking analysis, pharmacophore modeling, and molecular simulation. The results show the binding potential of the identified ligands to the amino acid residues, thereby suggesting an interaction of the amino acids with the ligand at the binding site of the glucokinase activator through conventional chemical bonds such as hydrogen bonds and hydrophobic interactions. The compatibility of the molecules was highly observed when compared with the standard ligand, thereby leading to structural and functional changes. Therefore, the bioactive components from Entada africana could be a good driver of glucokinase, thereby paving the way for the discovery of therapeutic drugs for the treatment of diabetes and its related complications.
Biogenic Silver Nanoparticles/Mg-Al Layered Double Hydroxides with Peroxidase-like Activity for Mercury Detection and Antibacterial Activity
Authors: Chamanmalik Masira I. , Antony Arnet Maria , Yelamaggad C. V. , Patil Shivaputra A. , Patil Siddappa A.
Published: July 2023

Over the past decade, the attention of researchers has been drawn to materials with enzyme-like properties to substitute natural enzymes. The ability of nanomaterials to mimic enzymes makes them excellent enzyme mimics; nevertheless, there is a wide berth for improving their activity and providing a platform to heighten their potential. Herein, we report a green and facile route for Tectona grandis leaves extract-assisted synthesis of silver nanoparticles (Ag NPs) decorated on Mg-Al layered double hydroxides (Mg-Al-OH@TGLE-AgNPs) as a nanocatalyst. The Mg-Al-OH@TGLE-AgNPs nanocatalyst was well characterized, and the average crystallite size of the Ag NPs was found to be 7.92 nm. The peroxidase-like activity in the oxidation of o-phenylenediamine in the presence of H2O2 was found to be an intrinsic property of the Mg-Al-OH@TGLE-AgNPs nanocatalyst. In addition, the use of the Mg-Al-OH@TGLE-AgNPs nanocatalyst was extended towards the quantification of Hg2+ ions which showed a wide linearity in the concentration range of 80–400 μM with a limit of detection of 0.2 nM. Additionally, the synergistic medicinal property of Ag NPs and the phytochemicals present in the Tectona grandis leaves extract demonstrated notable antibacterial activity for the Mg-Al-OH@TGLE-AgNPs nanocatalyst against Gram-negative Escherichia coli and Gram-positive Bacillus cereus.
Tyrosinase Inhibitors: A Perspective
Authors: Baber Mason A. , Crist Cole M. , Devolve Noah L. , Patrone James D.
Published: July 2023

Due to its integral role in the biosynthesis of melanin in all kingdoms of life, tyrosinase has become an extremely important target for inhibition in several sectors of research including agricultural and cosmetic research. Inhibitors of tyrosinase have made it to the market in the cosmetics industry, but their use has been limited due to conflicting efficacy and potential toxicity, which has led to several small molecules being removed from the market. Undaunted, researchers have continued to pursue tyrosinase inhibitors with varying degrees of success. These pursuits have built an impressive and rich library of research. This review is intended to provide a perspective of the past twenty years (2003–2023) of research on tyrosinase inhibitors by highlighting exemplar molecules and developments.
An Overview of the Nano-Enhanced Phase Change Materials for Energy Harvesting and Conversion
Authors: Pereira José , Moita Ana , Moreira António
Published: July 2023

This review offers a critical survey of the published studies concerning nano-enhanced phase change materials to be applied in energy harvesting and conversion. Also, the main thermophysical characteristics of nano-enhanced phase change materials are discussed in detail. In addition, we carried out an analysis of the thermophysical properties of these types of materials as well as of some specific characteristics like the phase change duration and the phase change temperature. Moreover, the fundamental improving techniques for the phase change materials for solar thermal applications are described in detail, including the use of nano-enhanced phase change materials, foam skeleton-reinforced phase change materials, phase change materials with extended surfaces, and the inclusion of high-thermal-conductivity nanoparticles in nano-enhanced phase change materials, among others. Those improvement techniques can increase the thermal conductivity of the systems by up to 100%. Furthermore, it is also reported that the exploration of phase change materials enhances the overall efficiency of solar thermal energy storage systems and photovoltaic-nano-enhanced phase change materials systems. Finally, the main limitations and guidelines for future research in the field of nano-enhanced phase change materials are summarized.
Ammonium N-(pyridin-2-ylmethyl)oxamate (AmPicOxam): A Novel Precursor of Calcium Oxalate Coating for Carbonate Stone Substrates
Authors: Pintus Anna , Aragoni M. Carla , Carcangiu Gianfranco , Caria Veronica , Coles Simon J. , Dodd Eleanor , Giacopetti Laura , Gimeno Domingo , Lippolis Vito , Meloni Paola , Murgia Simone , Navarro Ezquerra Antonia , Podda Enrico , Urru Claudia , Arca Massimiliano
Published: July 2023

Ammonium N-(pyridin-2-ylmethyl)oxamate (AmPicOxam), synthesized from O-methyl-N-(pyridin-2-ylmethyl)oxamate, was spectroscopically and structurally characterized and assayed as a novel precursor for the protection and consolidation of carbonate stone substrates. An in-depth characterization of treated and untreated biomicritic limestone and white Carrara marble samples was carried out by means of SEM microscopy, X-ray powder diffraction, helium pycnometry, determination of water transport properties, and pull-off tests. The improved solubility (1.00 M, 16.5% w/w) of the title compound with respect to ammonium oxalate (0.4 M, 5% w/w) results in the formation of a thicker protective coating of calcium oxalate (CaOx) dihydrate (weddellite) on marble and biomicrite samples after the treatment with 5% and 12% w/w water solutions, producing a reduction in the stone porosity and increased cohesion. Theoretical calculations were carried out at the DFT level to investigate both the electronic structure of the N-(pyridin-2-ylmethyl)oxamate anion and the hydrolysis reaction leading from AmPicOxam to CaOx.
Enhancing ASP Flooding by Using Special Combinations of Surfactants and Starch Nanoparticles
Authors: Al-Jaber Hasanain A. , Arsad Agus , Bandyopadhyay Sulalit , Abdurrahman Muslim , Abdulfatah Mohammad Yasin , Agi Augustine , Yusuf Suriatie Mat , Abdulmunem Abdulmunem R. , Tahir Muhammad , Nuhma Mustafa Jawad
Published: July 2023

This study aimed to address the challenges faced by mature oilfields in extracting substantial oil quantities. It focused on improving the efficiency of alkaline–surfactant–polymer (ASP) flooding technique, which is a proven tertiary recovery technology, to overcome scaling issues and other hindrances in its large-scale implementation. Appropriate materials and their suitable concentrations were selected to enhance the ASP flooding technique. Special surfactants from Indonesia were introduced to improve the interfacial tension reduction and wettability alteration. Reservoir rock model that resembling Langgak oilfield in Sumatra was utilized, and low-salinity water was employed to mimic the oilfield conditions. Starches derived from cassava nanoparticles (CSNPs) and purple yam nanoparticles (PYNPs) were combined separately with conventional hydrolyzed polyacrylamide (HPAM) polymer to enhance its performance. Sodium hydroxide and sodium carbonate were used as alkaline in final ASP formula. It was demonstrated from this research that only two combinations of ASP formulations have led to improved oil recovery. One combination utilizing PYNPs resulted in 39.17% progressive recovery, while the other combination incorporating CSNPs achieved 35% incremental oil recovery. The ASP combination that resulted in recovery rate of 39.17% was composed of sodium hydroxide (NaOH) at a concentration of 1.28 wt.%, PSC EOR 2.2 (0.98 wt.%), and a combined polymer consisting of HPAM (0.2 wt.%) and PYNPs nano-starch (0.6 wt.%). The second combination led to 35% recovery rate and involved NaOH also at concentration 1.28 wt.%, PSC HOMF (0.63 wt.%), and a combined polymer comprising from HPAM (0.2 wt.%) and CSNPs nano-starch (0.8 wt.%). These findings of this study highlighted the potential of this modified ASP flooding to enhance oil recovery in mature oilfields, thereby offering valuable insights for oil industry.
Manganese Removal Using Functionalised Thiosalicylate-Based Ionic Liquid: Water Filtration System Application
Authors: Basirun Ain Aqilah , Karim Wan Azlina Wan Ab , Wei Ng Cheah , Wu Jiquan , Wilfred Cecilia Devi
Published: July 2023

Aiming at the generation of new functionalised thiosalicylate-based ionic liquids, a polymeric hydrogel consisting of 1-hexylimidazole propionitrile thiosalicylate [HIMP][TS], with a solid biomaterial support based on polyvinyl alcohol (PVA)–alginate beads, was produced. This study aimed to develop a treatment method for removing manganese (Mn) heavy metal from industrial wastewater, which is known to be toxic and harmful towards the environment and human health. The method utilised an adsorption-based approach with an alginate adsorbent that incorporated a functionalised thiosalicylate-based ionic liquid. The synthesised smooth round beads of PVA–alginate–[HIMP][TS] adsorbent were structurally characterised using Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM). The Mn concentration and removal efficiency were evaluated using atomic absorption spectroscopy (AAS). Three important parameters were evaluated: pH, adsorbent dosage, and contact time. During optimisation using the interactive factor design of experiments through the Box–Behnken model, the results showed that the system achieved a maximum Mn removal efficiency of 98.91% at an initial pH of 7.15, with a contact time of 60 min, using a bead dosage of 38.26 g/L. The beads were also tested in an available water filtration prototype system to illustrate their industrial application, and the performance showed a removal efficiency of 99.14% with 0 NTU total suspended solid (TSS) and 0.13 mg/L turbidity analysis. The recyclability of PVA–alginate–[HIMP][TS] beads using 0.5 M HCl resulted in four cycles with constant 99% Mn removal. The adsorption capacity of Mn was also determined in optimum conditions with 56 mg/g. Therefore, the alginate–thiosalicylate-based ionic liquid system is considered an effective and environmentally friendly method for removing Mn heavy metal due to the high removal efficiency achieved.
Ultrasound-Assisted Anthocyanins Extraction from Pigmented Corn: Optimization Using Response Surface Methodology
Authors: Nurkhasanah Annisa , Fardad Titouan , Carrera Ceferino , Setyaningsih Widiastuti , Palma Miguel
Published: July 2023

This study aimed to determine the optimal UAE conditions for extracting anthocyanins from pigmented corn using the Box–Behnken design (BBD). Six anthocyanins were identified in the samples and were used as response variables to evaluate the effects of the following working variables: extraction solvent pH (2–7), temperature (10–70 °C), solvent composition (0–50% methanol in water), and ultrasound power (20–80%). The extraction time (5–25 min) was evaluated for complete recovery. Response surface methodology suggested optimal conditions, specifically 36% methanol in water with pH 7 at 70 °C using 73% ultrasound power for 10 min. The method was validated with a high level of accuracy (>90% of recovery) and high precision (CV < 5% for both repeatability and intermediate precision). Finally, the proposed analytical extraction method was successfully applied to determine anthocyanins that covered a wide concentration range (36.47–551.92 mg kg−1) in several pigmented corn samples revealing potential varieties providing more health benefits.
Unraveling the Mechanisms of Ch-SeNP Cytotoxicity against Cancer Cells: Insights from Targeted and Untargeted Metabolomics
Authors: Estevez Hector , Garcia-Calvo Estefania , Mena Maria L. , Alvarez-Fernandez Garcia Roberto , Luque-Garcia Jose L.
Published: July 2023

Although chitosan-stabilized selenium nanoparticles (Ch-SeNPs) have emerged as a promising chemical form of selenium for anticancer purposes, gathering more profound knowledge related to molecular dysfunctions contributes significantly to the promotion of their evolution as a chemotherapeutic drug. In this sense, metabolites are the end products in the flow of gene expression and, thus, the most sensitive to changes in the physiological state of a biological system. Therefore, metabolomics provides a functional readout of the biochemical activity and cell state. In the present study, we evaluated alterations in the metabolomes of HepG2 cells after the exposure to Ch-SeNPs to elucidate the biomolecular mechanisms involved in their therapeutic effect. A targeted metabolomic approach was conducted to evaluate the levels of four of the main energy-related metabolites (adenosine triphosphate (ATP); adenosine diphosphate (ADP); nicotinamide adenine dinucleotide (NAD+); and 1,4-dihydronicotinamide adenine dinucleotide (NADH)), revealing alterations as a result of exposure to Ch-SeNPs related to a shortage in the energy supply system in the cell. In addition, an untargeted metabolomic experiment was performed, which allowed for the study of alterations in the global metabolic profile as a consequence of Ch-SeNP exposure. The results indicate that the TCA cycle and glycolytic pathways were impaired, while alternative pathways such as glutaminolysis and cysteine metabolism were upregulated. Additionally, increased fructose levels suggested the induction of hypoxia-like conditions. These findings highlight the potential of Ch-SeNPs to disrupt cancer cell metabolism and provide insights into the mechanisms underlying their antitumor effects.
Insight into the Mechanisms of Nitride Films with Excellent Hardness and Lubricating Performance: A Review
Authors: Wu Xinmeng , Jiang Yaohong , Wu Tianhao , Zuo Bin , Bian Shunuo , Lu Kun , Zhao Lijun , Yu Lihua , Xu Junhua
Published: July 2023

Transition metal nitride (TMN) films with excellent hardness and lubricating performance are versatile low dimension materials, which are widely used in various fields including industries, transportation, aerospace, and so on. This paper introduces one film design strategy and provides a review of the mechanisms for strengthening and lubricating nitride films. The design strategy refers to two aspects which determine the structures, the performance, the components, and the chemical constitutions of nitride films The strengthening mechanisms of nitride films are then illuminated in detail, including the solid solution effect, the grain size effect, the secondary phase effect, the stress or stress field effect, the template effect, and the valence electron concentration effect. Five lubricating mechanisms are next summarized, including the easy-shear nature, the tribo-chemical reactions, the lubricious fluorides, the textured contact surface, and the synergistic effect. This paper aims to give a comprehensive introduction for understanding the mechanisms of strengthening and lubrication of nitride films for students and researchers, as well as to understand the current research progress in nitride films for exploring research gaps.
Synergistic Effects of Localized Surface Plasmon Resonance, Surface Plasmon Polariton, and Waveguide Plasmonic Resonance on the Same Material: A Promising Hypothesis to Enhance Organic Solar Cell Efficiency
Authors: Ibrahim Zamkoye Issoufou , Lucas Bruno , Vedraine Sylvain
Published: July 2023

This work explores the utilization of plasmonic resonance (PR) in silver nanowires to enhance the performance of organic solar cells. We investigate the simultaneous effect of localized surface plasmon resonance (LSPR), surface plasmon polariton (SPP), and waveguide plasmonic mode on silver nanowires, which have not been thoroughly explored before. By employing finite-difference time-domain (FDTD) simulations, we analyze the plasmonic resonance behavior of a ZnO/Silver nanowires/ZnO (ZAZ) electrode structure. Our investigations demonstrate the dominance of LSPR, leading to intense electric fields inside the nanowire and their propagation into the surrounding medium. Additionally, we observe the synergistic effects of SPP and waveguide plasmonic mode, contributing to enhanced light absorption within the active layer of the organic solar cell. This leads to an improvement in photovoltaic performance, as demonstrated by our previous work, showing an approximate 20% increase in photocurrent and overall power conversion efficiency of the organic solar cell. The incorporation of metallic nanostructures exhibiting these multiple plasmonic modes opens up new opportunities for improving light absorption and overall device efficiency. Our study highlights the potential of these combined plasmonic effects for the design and optimization of organic solar cells.
Air Stabilization of Li7P3S11 Solid-State Electrolytes through Laser-Based Processing
Authors: Eatmon Yannick , Stiles Joseph W. , Hayashi Shuichiro , Rupp Marco , Arnold Craig
Published: July 2023

All-solid-state batteries (ASSBs) that employ solid-state electrolytes (SSEs) have the potential to replace more conventional batteries that employ liquid electrolytes due to their inherent safety, compatibility with lithium metal and reputable ionic conductivity. Li7P3S11 is a promising SSE with reported ionic conductivities in the order of 10 mS/cm. However, its susceptibility to degradation through oxidation and hydrolysis limits its commercial viability. In this work, we demonstrate a laser-based processing method for SSEs to improve humidity stability. It was determined that laser power and scanning speed greatly affect surface morphology, as well as the resulting chemical composition of Li7P3S11 samples. Electrochemical impedance spectroscopy revealed that laser treatment can produce SSEs with higher ionic conductivities than pristine counterparts after air exposure. Further examination of chemical composition revealed an optimal laser processing condition that reduces the rate of P2S74− degradation. This work demonstrates the ability of laser-based processing to be used to improve the stability of SSEs.
The Ultra-Large-Bandwidth Cascade Full-Stokes-Imaging Metasurface Based on the Dual-Major-Axis Circular Dichroism Grating
Authors: Cheng Bo , Song Guofeng
Published: July 2023

A dual-major-axis grating composed of two metal–insulator–metal (MIM) waveguides with different dielectric layer thicknesses is numerically proposed to achieve the function of the quarter-wave plate with an extremely large bandwidth (1.0–2.2 μm), whose optical properties can be controlled by the Fabry–Pérot (FP) resonance. For the TE incident mode wave, MIM waveguides with large (small) dielectric layer thicknesses control the guided-mode resonant channels of long (short) waves, respectively, in this miniaturized optical element. Meanwhile, for the TM incident mode wave, the propagation wave vector of this structure is controlled by the hybrid mode of two gap-SPPs (gap-surface plasmon polaritons) with different gap thicknesses. We combine this structure with a thick silver grating to propose a circularly polarizing dichroism device, whose effective bandwidth can reach an astonishing 1.65 μm with a circular polarization extinction ratio greater than 10 dB. The full Stokes pixel based on the six-image element technique can almost accurately measure arbitrary polarization states at 1.2–2.8 μm (including elliptically polarized light), which is the largest bandwidth (1600 nm) of the full Stokes large-image element to date in the near-infrared band. In addition, the average errors of the degree of linear polarizations (Dolp) and degree of circular polarizations (Docp) are less than −25 dB and −10 dB, respectively.
Fabrication of Flexible PDMS Films with Micro-Convex Structure for Light Extraction from Organic Light-Emitting Diodes
Authors: Bae Eun-Jeong , Kim Yeon-Sik , Choi Geun-Su , Ju Byeong-Kwon , Baek Dong-hyun , Park Young-Wook
Published: July 2023

In this study, we demonstrated organic light-emitting diodes (OLEDs) outcoupling with a flexible polydimethylsiloxane (PDMS) film with a micro-convex structure using the breath figure (BF) method. We can easily control the micro-convex pattern by adjusting the concentration of polystyrene and the humidity during the BF process. As process conditions to fabricate the micro-convex structure, polymer concentrations of 10, 20, 40, and 80 mg/mL and 60, 70, and 80% relative humidity were used. To evaluate the optical properties, we analyzed the transmission, diffusion, and electroluminescence with or without the micro-convex structure on the OLEDs. The shape and density of the micro-convex structure are related to its optical properties and outcoupling and we have experimentally demonstrated this. By applying a micro-convex structure, it achieved up to a 42% improvement in the external quantum efficiency compared to bare OLEDs (without any light extraction film). We expect the fabricated flexible light extraction film to be effective for outcoupling and applicable to flexible devices.