bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating predictive hybrid neural network models in spatiotemporal context: An application on Influenza outbreak predictions
Authors: Furkan Hamed Bin , Ayman Nabila , Uddin Md. Jamal
Published: December 2023

In the rigorous and varied field of infectious disease outbreak modeling, there remains a notable gap in addressing the spatiotemporal challenges present in established models. This study aimed to fill this gap by evaluating four already established hybrid neural network models designed to predict influenza outbreaks, given that influenza is a major infectious disease. These models were analyzed by employing time series data from eight different countries which is a deviation from the original articles to challenge the models with imposed spatial difficulties, in a month-on-month structure to assess their abilities to handle spatiotemporal dependencies. The models' predictions were compared using MAPE (Mean Absolute Percentage Error) and RMSE (Root Mean Squared Error) metrics, as well as graphical representations of the original values and predicted values generated by employed models. The GA-LSTM model yielded the lowest MAPE score of 62.38% followed by GA-ConvLSTM-CNN model with a MAPE score of 66.23% among all the models, and the SARIMA-LSTM model excelled in achieving the lowest average RMSE score of 66.93 as well as reporting the lowest RMSE score for three out of eight countries studied. In this case also, GA-ConvLSTM-CNN model comes in second place with an average RMSE score of 68.46. Considering these results and the ability to follow the seasonal trends of the actual values, this study suggests the SARIMA-LSTM model to be more robust to spatiotemporal challenges compared with the other models under examination.
Association of induced abortion with bipolar disorder and major depression from the UK Biobank: A Propensity Score Matching and Weighting Analysis
Authors: Sun Hao , Huang Jie , Liu Huan , Chen Yanjie , Dong Yongfei , Chu Ziyan , Sun Hongpeng , Tang Zaixiang , Liu Jingfang
Published: December 2023

Background:Female induced abortion is associated with anxiety and depression, However, fewer studies have focused on the association between induced abortion and bipolar disorder and major depression (BDMD).
Objectives: This study aimed to investigate the association between IA and BDMD, and the possible dose-response relationship between them.
Methods: We conducted a cross-sectional study of 13,200 female UK
Biobank participants. Self-reported number of IAs was categorized into two groups: Non-IA and IA, Moreover, we also explored the number of IA episodes. Covariates adjustment, propensity scores matching (PSM), and inverse probability of treatment weighting (IPTW) were conducted to correct and minimize bias.
Results: The IPTW-multivariate logistic regression revealed the OR was 1.25(95%CI:1.19-1.32) and the PSM-multivariate logistic regression revealed the OR was 1.25(95%CI:1.10-1.41) in the IA group, The different number of IAs were also correlated with BDMD,p for trend was <0.05. There was a nonlinear relationship between the number of IAs and the risk of BDMD according to the three-knots restricted cubic spline regression model. Similar conclusions were obtained from the sensitivity analysis.
Conclusion:IA was an independent factor for BDMD, Care for mental health care for women after spontaneous abortion is crucial.
Sp3-rich Porous Carbon for Doublet Layer Supercapacitors
Authors: Bhattacharyya Tamoghna
Published: December 2023

Efficient utilization of alternative energies hinges on the performance and cost of energy storage systems. In the foreseeable future, supercapacitors remain the most promising option for many energy storage applications. But their widespread use is limited by their low energy storage density and relatively high effective series resistance. To date, however, the highest energy density of a carbon-based solid-state supercapacitor is limited up to 139 Wh kg− 1. Here, we report our findings in the synthesis of a sp3 -rich carbon through a simple, one-step process and direct insertion of pyridinic and graphitic nitrogen in an NH3 atmosphere at -780C. Further, the hetero atom doped sp3 -rich carbon materials-based doublet layer supercapacitors with ordered architecture and shorter diffusion path & lower resistance, demonstrated excellent energy density (218.4 Wh kg− 1) with excellent cycling stability. This simple approach to low-cost carbonaceous materials with unique architecture and functionality could be a promising alternative to fabrication of hetero atom doped carbon structures for making next generation high capacitive batteries and hence, high energy storage device.
DFT study on the electronic, structure, magnetic and optical properties of TiO2 anatase
Authors: Sadek Otmane , Touhtouh Samira , Hajjaji Abdelowahed
Published: December 2023

In this work, the electronic structure, magnetic and optical properties of the anatase phase of titanium dioxide (TiO2) were etudiée by the Density Functional Theory (DFT) method, using the GGA+U method. As a result, the magnetic electronic properties show that anatase is a non-magnetic semiconductor with an indirect gap of 3.202. Optical properties such as dielectric function, refractive index, extinction coefficient, reflectivity, absorption coefficient and conductivity were found to be 8.21, 2.91, 1.98, 0.532, 517000 cm-1 and 8.9 fs-1 respectively. These results are in agreement with the available experimental results.
Hydrochemical Characteristics and Genesis of Ore-Rich Brine in the Lingbei Area of the Jiangling Depression, Jianghan Basin
Authors: Liu Yanting , Wang Chunlian , Ding Ting , Liu Dianhe , You Chao , Liu Xue
Published: December 2023

The brine resources in the Jianghan Basin have abundant reserves. In the Lingbei area of the Jiangling Depression, the brine resources from the Late Cretaceous to Lower Eocene strata have high salinity and rich mineral ion resources. These resources exceed the comprehensive utilization grade and some areas even exceed the industrial grade, indicating broad prospects for development and utilization. In this study, twelve brine samples were collected from the Lingbei area of the Jiangling Depression. The chemical characteristics, element correlation, characteristic coefficient, and isotope characteristics of the brine were analyzed based on the test results. The average salinity of the brine samples was 192.05g/L, and the hydrochemical type was chloride. Correlation analysis revealed that water-rock reactions in various underground reservoirs, such as sandstones and basalts, contributed a significant amount of salt materials. The characteristic coefficient analysis indicated obvious characteristics of sedimentary underground brine, good sealing, and high metamorphism. Furthermore, the analysis of δD-δ18O isotopes suggested that the water samples originated from terrestrial atmospheric precipitation, as they were all on the right side of the atmospheric precipitation.
Estimation of evapotranspiration and its components of greenhouse grapevines under drip irrigation in the cold region of northeast China using Dual-source models
Authors: Wei Xinguang , Zheng Siyu , Cui Ningbo , Wang Zhihui , Wang Tieliang , Zha Yuxuan , Bai Yikui
Published: December 2023

Accurate determination of crop evapotranspiration (ET) in the greenhouse is critical for making scientific irrigation decisions and improving water productivity. In this study, the dynamics of grapevine latent heat (LE), ET and its components were monitored from 2017 to 2019, 2021 by using sap flow + micro-lysimeters and environmental monitoring system. The Penman-Monteith dual crop coefficient (PM), Shuttleworth-Wallace (SW) model and modified SW model (SWm) which was proposed considering the effect of the surface resistance difference between wet and dry soil under drip irrigation, were applied to simulate evaporation (E), transpiration (T) and ET. The results showed that SW and SWm models overestimated T (overestimation rate was 3-11%), while the PM model significantly underestimated T (underestimation rate was 9-18%). The simulation accuracy of three models for E was in the order of SWm>SW>PM. Compared with the SW model, SWm model could significantly reduce the simulation error of E and improved the simulation accuracy (R2 is increased from 0.75-0.81 to 0.92-0.94), while PM model had a poor simulation effect on E (R2 is 0.74-0.89, RMSE is 0.16-0.23mm d-1). ET was underestimated by PM model (underestimation rate was 4-38%) but overestimated by SW and SWm models (overestimation rate was 3-33%). All three models had high simulation accuracy for grapevine ET (R2 >0.97, RMSE is 0.25-0.50 mm d-1), and simulation accuracy of ET was in the order of SWm>SW>PM. Therefore, the SWm model is recommended to simulate ET and its components of greenhouse grapevines in the cold region of northeast China.
Optimization Method for Denoising Yarn Tension Signals Based on Empirical Wavelet Transform and Adaptive Wavelet Threshold Denoising
Authors: Peng Laihu , Hou liangmei , Qi Yubao , Li Jianqiang , Zhai Ziyong
Published: December 2023

In the weaving process, yarn tension signals are adversely affected by a considerable amount of uncertain noise sequences, compromising the closed-loop control accuracy of yarn tension. Particularly challenging is the effective preservation of these features when confronted with sudden changes in yarn tension characteristics. To address this issue, we propose an Adaptive Wavelet Threshold Denoising (WTD) optimization method for yarn tension signals based on Empirical Wavelet Transform (EWT). The application of EWT decomposes yarn tension signals into components of different frequencies and scales, with wavelet thresholding used for threshold processing of the decomposed signals. The effectiveness of the proposed method is validated through simulation experiments and on-site data analysis. Results indicate that, compared to the PSO-VMD method and the FastICA method, the SNR after processing with the proposed method is improved by 8.55% and 26.29%, respectively. Root Mean Square Error (RMSE) shows that the denoising result curve of this method fits the simulated data curve more closely, and the sudden changes in the signal characteristics are better preserved. Experimental data verification demonstrates the superior performance of the proposed method in denoising tension signals with three different characteristics, with the SNR being maximally improved by 5.32dB while fully preserving the sudden changes in the signal. The proposed method exhibits excellent denoising effects in experiments on yarn tension signals collected at different speeds on a circular winding machine, with a maximum SNR improvement of 5.29dB. It adapts well to the changes in signals that occur under different operating conditions. This method provides a feasible solution for improving the stability and production efficiency of yarn tension in knitting systems.
Integrated Fault Detection in AC Induction Motors Using Electrical and Vibration Signals
Authors: Hamdi Faouzi , Felahi Saci
Published: December 2023

This article emphasizes the importance of identifying faults in critical components, particularly rotor bars. Rotor bars are integral parts of the motor's rotor assembly, and any damage or faults in these components can significantly impact the motor's overall performance. The main focus of the article is to explore a method for detecting faults in AC induction motors, with a specific emphasis on identifying broken rotor faults. The method involves a systematic approach to fault detection that utilizes both electrical and vibration signals generated by the motor.
Simultaneous dynamic processing strategies of hybrid wire arc additive-milling subtractive manufacturing based on stability region simulation and stiffeners assistance
Authors: Zhang Shuai , Gong Mengcheng , Gao Ming
Published: December 2023

Hybrid wire arc additive-milling subtractive manufacturing (HWMM) represents an innovative digital direct manufacturing approach for crafting intricate and low-volume structural components by using the two processes alternately. In order to solve the question that the chatter easily occurs and results in the instability of the milling due to the dynamic deposition of the HWMM, a modelling of HWMM was developed by the finite element modal analysis in this paper. Then, a stability region dynamic lobe diagram was drawn according to the dynamic model of robotic milling system "rigid tool-flexible workpiece", which can predict the optimal parameters. Within this parameter optimization range, milling tests demonstrated an absence of chatter. Furthermore, the prediction results of randomly selected parameters within the stable region are in good agreement with the experimental data. Notably, the milling vibration mean and Ra values for the externally chattered sample were 10.5 times and 4.1 times higher, respectively, than those of the stable milling sample devoid of chatter in the same region. In addressing the challenge of diminishing optimization window width with increasing deposition height, and to enhance stability, the impact of stiffeners on natural frequency was investigated. The study revealed that the T-shaped and J-shaped stiffeners induced the most substantial increase in natural frequency, presenting a promising avenue for expanding the process window. A simultaneous dynamic milling strategy of HWMM is proposed based on the stability region simulation and stiffeners assistance, which can determine quickly, and broaden the milling window, and improve the accuracy and efficiency.
Extracellular vesicle-mediated transfer of BACH1 from macrophage promotes vascular smooth muscle cell proliferation via suppressing FNDC5 expression
Authors: Tong Ying , Wang Dan-Dan , Lu Tao , Zhou Mei-Hui , Chen Dan , Wu Ya-Xian , Fang Fei , Pang Qing-Feng
Published: December 2023

Objectives: Extracellular vesicles (EVs) derived from macrophages play crucial roles in the proliferation of vascular smooth muscle cells (VSMCs) and hypertensive vascular remodeling. However, the role of BTB and CNC homology 1 (BACH1) in the EVs regulates VSMC proliferation and vascular remodeling is still unclear.
Methods: Normotensive Wistar-Kyoto rat (WKY) and spontaneously hypertensive (SHR) rat were used as animal models. Primary macrophages and VSMCs were used to study the molecular mechanism. Ultracentrifugation was performed to isolate EVs from macrophages collected from WKY rats (WKY-EVs) and SHR rats (SHR-EVs).
Results: The level of BACH1 in SHR-EVs was significantly higher than that in WKY-EVs. Compared with WKYs, the expression of fibronectin type III domain (FNDC5) in SHR VSMCs decreased, while the content of BACH1 increased. Double luciferase reporter analysis showed that FNDC5 was the target gene of BACH1. FNDC5 improved the proliferation-promoting effect of SHR-EVs in VSMCs. Moreover, SHR-EVs inhibited the expression of FNDC5, but promoted proliferation in VSMCs, and these effects were reversed by the treatment with SHR-EVs from the BACH1 knockdown-treated macrophages. Knockdown of BACH1 reversed the down-regulation of FNDC5, hypertension, VSMC proliferation and vascular remodeling in SHR. Repeated intravenous injection of SHR-EVs increased blood pressure and vascular BACH1 contents, and promoted vascular remodeling of WKYs and SHRs, while WKY-EVs decreased vascular BACH1 and weakened hypertension and vascular remodeling of SHR.
Conclusion: Increased BACH1 in the SHR-EVs enhances VSMC proliferation in SHR by inhibiting FNDC5 expression, and that intervening EV-mediated transfer of BACH1 and inhibition of BACH1 expression in macrophages or up-regulation of FNDC5 may be effective therapeutic strategies in attenuating VSMC proliferation in hypertensive vascular remodeling.
Siamese YOLO V5 with Structure coefficient for object-level change detection
Authors: Zhang Yi , Pang Jie , Li Baicheng , Luo Jianfeng
Published: December 2023

Change detection is a task to identify the location and category of change objects in the reference image and the test image within a specific time interval, that can reduce workload and increase efficiency and reliability in applications such as foreign object intrusion, equipment status monitoring, building or natural resource monitoring, military anomaly monitoring, and so on. To deal with the complicated noise such as dithering, weather, lighting, shadows and background noise in the actual situations, this research combined the Siamese network in conjunction with advanced object detection for object-level change detection. The Siamese network with Structure coefficient is used to extract the fusion difference information between the reference image and the test image to be measured to resist the registration error and unrelated interference between images, which is used for YOLO V5 to detect the effective rectangular boxes and category of the change objects. Four public datasets of different scenes include LEVIR-CD, VL-CMU-CD, AICD-2012 and CDNET-2014 are used in multiple comparative experiments, and the experimental results proved that our method achieved higher accuracy than existing object-level methods and less false detections than existing pixel-level methods.
Measurement of air kerma and absorbed dose to water using radiophotoluminescence glass dosimeters with different radionuclide beams.
Authors: MATHUTHU MANNY , JOHN SAMUEL ODUMU OGANA , SEEPAMORE DITHOLE , MASELESELE VINCENT
Published: December 2023

Radiophotoluminescence Glass Dosimeters (RPLGDs) are part of the luminescence family of dosimeters just like Thermoluminescence Dosimeters (TLDs). For years now, Panasonic TLDs have been used for both personal and environmental monitoring in South Africa and have limitations. Although both TLDs and RPLGDs utilise thermoluminescence phenomenon, exceptional properties of RPLGDs are studied. Three radiation sources (i.e., 60Co, 137Cs, & 241Am) were used to characterize the response of RPLGDs when exposed to different radiation doses. Ability of RPLGDs to be read more than once without losing original signal was studied. RPLGDs were investigated for their ability to measure both personal and environmental monitoring. Substitution method was used to determine the reference measurements on all radiation source setups. Two ionization chambers were used as reference detectors and RPLGDs as the Unit Under Test (UUT) on each radiation source setup. Dose rates were used to determine the time of the prescribed radiation doses. RPLGDs were exposed to the same time as the reference detectors to accumulate radiation signal which was corrected to determine air kerma and absorbed dose to water. All the corrections that affected the response of UUT were implemented on the final readings to characterise RPLGDs by comparing with the prescribed dose.
The effects of two high-intensity interval training protocols on serum levels of Glypican-4 in an overweight and obese female population.
Authors: Ramin Amirsasan , dolataabadi parvane , Javad Vakili , S Baker Julin
Published: December 2023

Objectives: The purpose of this study was to investigate the effects of two high intensity training protocols on serum levels of, Glypican-4 in overweight and obese women.
Design, Methods: Thirty-seven overweight and obese females were randomized into three groups, a HIIT (n=12), HICT (n=12) and a control group (n=13). The training groups performed three training sessions per week for a duration of ten weeks. Anthropometric measurements and blood samples were collected at baseline and following ten weeks of training. Statistical analysis was performed using SPSS version 26.
Results: Post ten weeks training, glypican-4 concentration (HIIT: p=.015, HICT: p=.014) HOMA-IR (p<0.001), fasting glucose (p<0.001), fasting insulin (HIIT: p=.015, HICT: P=.037), body weight (p<0.001), body mass index (p=0.001), body fat percentage (p<0.001), FM (p <0.001), WC (p<0.001), WHR (p< 0.001) significantly decreased in the training groups when compared with baseline values. These variables also significantly decreased in the training groups when compared to the control group (p<0.05). There was also a significant group x time interaction effects observed during the analysis, and decreases were also noted when comparisons with the control group were made.
Conclusions: The findings suggest that both HIIT and HICT exercise training protocols effectively decrease glypican-4 concentrations while improving anthropometric profiles in overweight and obese females.
Inducing the Localization of HSP70 to Lipid Rafts by Borna Disease Virus 1 Promotes Its Invasion and Host Cells Apoptosis
Authors: Lei Yang , Yang HongLi , Xu Xiaoyan , Tan Qing , Xiang Yayun , Tan Tingting , Deng Hongmei , Nie Yaxin , Xie Peng
Published: December 2023

The Borna disease virus 1 (BoDV-1) is an emerging zoonotic virus causing severe and mostly fatal encephalitis in humans. Increasing evidence of human infections by BoDV-1 has highlighted the importance of antiviral drugs against BoDV-1. However, the process of BoDV-1 infection and its pathogenic mechanism remain elusive and there are few drugs targeting BoDV-1 infection. Our previous research suggests that BoDV-1 infects cells through lipid-related pathways. Heat shock protein 70 (HSP70) in lipid rafts (LR) has been identified to participate in various viral infections. In this study, we reported that the LR-HSP70-Caspase-3 axis engages BoDV-1 invasion and host cell apoptosis. Mechanistically, the LR inhibitor, Methyl-β-cyclodextrin (MβCD), interferes the localization HSP70 to LR and prevents BoDV-1 entry without reducing cell viability.Furthermore, we confirmed that the HSP70 is recruited into LR after BoDV-1 invasion by HSP70 knockdown and overexpression assays. And the migration of HSP70 to LR weakened the interaction between HSP70 and Caspase-3, which reducing the chaperone protective ability of HSP70 to Caspase-3, increasing the intracellular active Caspase-3 and promoting host cell apoptosis. Importantly, the MβCD treatment can effectively alleviate the symptoms and pathological changes in a model of BoDV-1 encephalitis, suggesting a significant antiviral effect in vivo. Our report reveals the process of BoDV-1 invasion and the mechanisms by which MβCD inhibits the infection, offering potential guidance for the development in the targeted treatment of BoDV-1 infection.
Current status of self-management efficacy and its correlation with post-traumatic growth、resilience in nasopharyngeal carcinoma patients treated with radiotherapy:A cross-sectional study
Authors: Lu Shiyu , Ye Hongfang , Wang Juan
Published: December 2023

Objective To investigate the status of self-management efficacy and its correlation with Post-traumatic Growth and resilience in patients with NasoPharyngeal Carcinoma treated with radiotherapy, and to explore the influencing factors.
Methods In March to December 2022, NasoPharyngeal Carcinoma radiotherapy patients in a Class ⅲ Grade a hospital in Nanjing were selected as the research objects by convenience sampling. The general information Questionnaire, Cancer Self-Management Efficacy Scale, Post-traumatic Growth Rating Scale and 10-item Psychological Resilience Scale were used to investigate the patients. Pearson、Spearman correlation analysis and Hierarchical regression analysis were used to analyze the influencing factors of self-management efficacy of NasoPharyngeal Carcinoma radiotherapy patients.
Results In this study, the current score of self-management efficacy of NasoPharyngeal Carcinoma radiotherapy patients was (93.80±24.13). Pearson correlation analysis showed a positive correlation between self-management efficacy and post-traumatic growth in nasopharyngeal carcinoma radiotherapy patients (r=0.630, P < 0.01), and Spearman correlation analysis showed a positive correlation between self-management efficacy and mental toughness (r=0.509, P < 0.01).The results of hierarchical regression analysis showed that post-traumatic growth and resilience could positively predict the subjects' self-management efficacy after controlling individual characteristics variables, DR2=0.348, and the two could explain 34.8% of the total variables, and the cumulative could explain 47.4% of the total variables.
Conclusions In this study, the self-management efficacy of NasoPharyngeal Carcinoma patients undergoing radiotherapy is at a medium level, and Post-traumatic Growth and psychological resilience are the influencing factors. Medical staff should pay more attention to the negative emotions of patients and adopt reasonable intervention methods to enhance their self-management efficacy.
The association between self-rated autistic traits, social camouflaging, and mental health outcome in Taiwanese anime, game and comic (ACG) doujin creators: An exploratory study
Authors: Kuo Yen-Chun , Ni Hsing-Chang , Liu Chun-Hao
Published: December 2023

Background
Doujin (どうじん) is a Japanese term referred to a circle where people share the same interests, usually something that belongs to Anime, Comics, and Games (ACG) subculture. Individuals who belong to it and create related works, known as ACG doujin creators, are usually described as being socially awkward and are under potential risk of isolation. In such a context, they may theoretically exhibit heightened levels of autistic traits, manifest camouflaging tendencies and consequently have effects on their mental health. Nonetheless, the impact of autistic trait and camouflaging on mental health in this subculture remains significantly underexplored.
Methods
We recruited 183 Taiwanese ACG doujin creators (age ranges from 18 to 41, 146 female and 37 male) via social networking platforms. Participants completed Chinese online surveys assessing socio-demographic information, doujin activities, past psychiatric history, the 35-item Version of Autism-Spectrum Quotient (AQ-35), Chinese version Camouflaging Autistic Traits Questionnaire (CAT-Q-Ch), the General Anxiety Disorder-7 (GAD-7), and the Patient Health Questionnaire-9 (PHQ-9). Linear regression analysis was employed to examine the associations between the aforementioned scales.
Results
Our findings revealed that among ACG doujin creators, there were no significant sex differences in any of the scales examined. Moreover, we observed a positive association between camouflaging behavior and most AQ-35 subscales after controlling of age and sex, with the exception of the mindreading subscale. Additionally, we identified that camouflaging and autistic traits, rather than sex, were significantly linked to higher scores of PHQ-9 and GAD-7.
Conclusions
Through this study, we gained insight into the distinctive characteristics of autistic traits, camouflaging behaviours, and mental health among Taiwanese ACG doujin creators, as the findings are divergent compared to previous research. This topic may hold significant promise for further investigation.
Analysing Spatiotemporal Drought Patterns in Punjab Province, Pakistan, Utilizing SPI and SPEI
Authors: Hussain Anwar , Suliman Muhammad
Published: December 2023

The Standardized Precipitation Index (SPI) and Standardized Precipitation Evapotranspiration Index (SPEI) are applied in this study to examine drought features at different Punjab Province stations. We examine drought occurrence through drought frequency, concentrating on spatial and temporal scales and considering different geomorphologies. A modified Mann-Kendall test and multiple linear regression are used to examine monthly data from 12 weather stations collected between 1980 and 2020. Stations at high elevations have very variable precipitation, which can lead to periodic droughts. Surprisingly, SPEI shows more drought sensitivity than SPI. The severity of the drought has decreased recently, especially after the 1998–2002 peak period. Correlation analysis demonstrates a substantial link between SPI and SPEI at high elevation stations, with Murree displaying the strongest correlation (0.9334) on a one-month time frame, and Bahawalpur exhibiting a comparably lower correlation (0.6824). Positive trends in SPI and SPEI values are revealed by Mann-Kendall trend tests, which are most prominent at higher elevations and on the northern side of Punjab. On a one-month time scale, the Mianwali station has the strongest trend in SPEI (0.1497), whereas Bahawalnagar has negligible trends in both SPI (0.0214) and SPEI (0.0459). At high elevation sites, the frequency of drought is constantly high, and SPEI routinely detects greater drought at low elevations. Similar drought frequencies are shown by both indexes for the northern region of Punjab. The results of a multiple linear regression model demonstrate the significant impact of meteorological variables on monthly mean precipitation, which advances our knowledge of Punjab's spatiotemporal drought dynamics and provides important information for planning for resilience and water resource management.
Spondias mombin flavonoids showed super-binder ability with Downstream Molecular Targets of Parkinson’s Disease: Folkloric-therapy assessment as a Scaffold for Structural Studies in Neurodegenerative disease
Authors: Olanrewaju John A. , Arietarhire Leviticus O. , Soremekun Oladimeji E. , Olugbogi Ezekiel A. , Afolabi Toluwanimi O. , Oyinloye Babatunji E. , Omotuyi Olaposi I. , Russell Steven
Published: December 2023

Spondias mombin (S. mombin), a prominent botanical resource, has garnered recognition within folkloric therapy. Parkinson's disease (PD), characterized by dopaminergic neuron attrition in the substantia nigra, manifests as motor anomalies like tremors, rigidity, and bradykinesia. This study capitalizes on S. mombin's reservoir of 100 characterized phytocompounds and employs computational methodologies to interrogate their potential 35 PD-associated target proteins. Employing a multifaceted approach, we engaged in molecular docking, ADMET predictions, Molecular Mechanics/Generalized Born Surface Area (MM/GBSA) evaluations, Density Functional Theory (DFT), and Molecular Dynamic Simulations (MDS). This comprehensive framework facilitated insightful structural assessments and predictive analyses. Impressively, flavonoids hailing from S. mombin, including quercetin, catechin, ellagic acid, and epicatechin, showcased optimal binding affinities for PD-relevant target proteins. Moreover, these identified ligands exhibited minimal signs of mutagenicity, tumorigenicity, or irritancy, except for quercetin, which displayed elevated tumorigenic potential. Notably, quercetin and dopamine exhibited varying band gap energies, with quercetin the lowest (3.63 eV) and dopamine the highest (5.76 eV) values. MDS result suggests a synergistic outcome based on the RMSD and RMSF graphs for quercetin highlighting it as the best of all including the co-ligand. In a collective sense, our findings present S. mombin as promising reservoirs of active pharmaceutical ingredients, warranting further exploration for novel PD therapeutic avenues. Consequently, this study underscores the enhanced efficacy of phyto-ligands sourced from S. mombin, advocating their optimization as potential drug candidates.
Exploring Economic Adaptations: Qualitative Insights into the Metal Industry Amidst Shifting Towards Renewable Energy
Authors: Reynolds Samantha , Anderson Lily
Published: December 2023

This qualitative study delves into economic adaptations observed within the metal industry in response to the transition towards renewable energy sources. Through semi-structured interviews with key industry stakeholders, the research aimed to uncover strategic shifts, challenges, and opportunities encountered by metal companies amid this transformative phase. The methodology involved in-depth semi-structured interviews, allowing for comprehensive exploration of experiences, perspectives, and strategic maneuvers within the metal industry. Thematic analysis of these interviews offered insights into how companies are adapting their practices to align with the demands of renewable energy technologies. Findings from the study revealed a deliberate shift in the industry's focus towards critical metals essential for renewable energy applications, such as lithium and rare earth elements. This adaptation involves significant investments in retooling production lines and exploring novel extraction methods to meet the burgeoning demand. Challenges related to ensuring a resilient supply chain emerged prominently. The industry faces risks associated with geopolitical tensions and market fluctuations, prompting the exploration of diversified sourcing strategies and alternative reserves to fortify the supply chain against disruptions. The study's limitations lie in its qualitative nature, limiting broader quantitative assessments, and the snapshot nature of the research, capturing dynamics at a specific time frame. Practically, the research offers valuable insights for industry stakeholders, guiding strategic decision-making, supply chain fortification, and market diversification efforts. Socially, the alignment of the industry with renewable energy transitions holds promise for enhanced sustainability and reduced environmental impacts. This study contributes original insights into economic adaptations within the metal industry amidst the shift towards renewable energy sources, offering a nuanced understanding of industry responses and their implications. However, the qualitative approach may limit generalizability, and continuous monitoring is necessary to track long-term industry trends.
A review on medicinal and ethnomedicinal uses, biological features, and phytochemical constituents of Sesbania sesban L. Merr., a nitrogen-fixing plant native to the Republic of Chad
Authors: Mahamat Ousman Brahim , Younes Saoud , Otchom Boy Brahim , Franzel Steven , Hidjazi Al-Djazouli Ouchar Mahamat , Soumaya El Ismaili
Published: December 2023

This study reports on a literature review of the leguminous tree Sesbania sesban (L.) Merr is found in the N'Djamena region, the Republic of Chad. The study focused on S. sesban’s medicinal and ethnomedicinal uses, biological features, and phytochemical constituents to assist in future evaluations. A literature review was conducted using academic websites, such as Science Direct and Springer, online international plant databases, and data from national herbaria. S. sesban is a perennial shrub or tree that measures 3–4 meters in height. This species is becoming rare in Ndjamena but can be found in the rainy season, while in winter, the species occurs mainly in ponds (called in the Chadian dialect "Bouta"), and in the shores of the Chari and Logone rivers. The local inhabitants in Chad use the species as medicine, livestock feed, fuelwood, and for improving soil fertility and repelling desert encroachment. Traditional healers use its leaves to treat breast cancer and edema. S. sesban is an essential species native to the Republic of Chad that needs conservation and valorization. Viewing its importance and rarity in N’Djamena, a strategy for replanting the species in gardens, homes, and fields around Ndjamena and other regions of Chad is recommended.
GALLE (GELİR) ALACAĞI
Authors: SUCU Kübra
Published: December 2023

743 sayılı Medenî Kanun’un kabulünden sonra mazbut ya da mülhak vakıf olarak kurulan zürrî vakıfların malvarlığı üzerindeki hak sahipliği hem 2762 sayılı mülga Vakıflar Kanunu hem de 5737 sayılı Vakıflar Kanunu ile belirli koşullara bağlı olarak muhafaza edilmiştir. Bu kapsamda mazbut ve mülhak vakıflarda vakfın hayrat ve akarlarının onarımı ile vakfiyelerindeki hayrat hizmetlerinin ifasından sonra kalan miktarı ifade eden galle fazlası üzerindeki hak korunmaktadır. Galle fazlasına ilişkin olarak Vakıflar Yönetmeliği’nde ayrıntılı düzenlemelere yer verilmiştir. Söz konusu düzenlemelere göre kişinin galle fazlası alabilmesi için galle fazlası almaya hak kazandığını gösterir bir mahkeme kararına sahip olması gerekmektedir. Belirtmek gerekir ki kişinin böyle bir mahkeme kararı alabilmesi için vakfiyede galle fazlası şartının bulunması ve vakfedenin soyundan gelindiğinin de ispatlanması şarttır. Galle fazlası almaya hak kazanmanın bir diğer şartı ise Kanun gereğince birtakım giderler düşüldükten sonra galle fazlası olarak ödenecek miktarın kalmış olmasıdır. Çalışmada kişilerin eski vakıflarda galle fazlası üzerindeki hak sahipliği kapsamında vakıf ve galle alacağı kavramları üzerinde durularak, galleye müstehik vakıf evladı olduğunun tespiti davasına ilişkin incelemeler yapılacaktır.
Polyphenolic compounds and ascorbic acid of plants of the genus Arctium L. introduced in the M. M. Hryshko National Botanical Garden
Authors: Sokol O. V. , Rakhmetov D. B. , Dzhurenko N. I. , Palamachuk O. P.
Published: December 2023

Purpose. To study the accumulation of catechins, anthocyanins, leucoanthocyanins and ascorbic acid in plants of the genus Arctium, introduced to the M. M. Hryshko National Botanical Garden. Methods. Introduced plants of the genus Arctium were used for the study, namely A. lappa L. (greater burdock), A. tomentosum Mill. (woolly burdock), A. nemorosum Lej. (wood burdock) and A. minus Bernh (lesser burdock). Phytochemical analyses of plant organ samples were carried out at different stages of ontogeny. Free catechins, anthocyanins and leucoanthocyanins were determined by the photocolorimetric method. Results. It was found that second year plants accumulate more catechins than first year plants. Their maximum amount is found in the leaf plates of A. lappa and A. minus in the budding phase (180.0 ± 0.3 and 144.0 ± 0.1 mg%, respectively). The content of leucoanthocyanins in the leaf plates of one­year­old plants varied from 72.0 ± 0.4 (A. lappa) to 660.0 ± 0.6 mg% (A. minus); two­year­old plants – from 18.0 ± 0.6 (A. nemorosum) to 165.0 ± 0.5 mg% (A. lappa). Most of these compounds were found in the leaf blade of A. minus in the first year of vegetation. The amount of anthocyanins in leaf plates of one­year­old plants varied from 9.0 ± 0.1 (A. nemorosum) to 42.0 ± 0.4 mg% (A. minus), in petioles from 9.8 ± 0.06 (A. tomentosum) to 117.0 ± 0.6 mg% (A. minus). In the second year of vegetation, their accumulation ranged from 12.0 ± 0.3 (A. minus) to 42.0 ± 0.6 mg% (A. tomentosum) in leaf plates and from 9.6 ± 0.1 (A. tomentosum) to 48.0 ± 0.1 mg% (A. nemorosum) in petioles. Most anthocyanins were found in the petioles of A. minus from the first year of vegetation. Conclusions. The phytochemical studies established that plants of the Arctium genus, introduced to the
M. M. Hryshko National Botanical Garden, accumulate varying amounts of phenolic compounds during the growing season. The proportion of flavonoids in leaves was found to be related to air temperature. An increase in temperature leads to a decrease in the content of anthocyanins, while an increase in catechins occurs due to a decrease in temperature. The leaf plates of annual plants belonging to the Arctium genus accumulate the highest levels of ascorbic acid.
Formation of productivity of amaranth varieties in the Right Bank Forest Steppe of Ukraine under the influence of MaxiMarin absorbent
Authors: Yatsenko V. V. , Yatsenko N. V., , Rogalskyi S. V. , Sichkar A. O. , Novak Y. V.
Published: December 2023

Purpose. To carry out an economic evaluation of amaranth varieties ‘Kharkivskyi­1’, ‘Helios’ and ‘Sem’ for the application of MaxiMarin absorbent used to compensate for lack of rainfall and uneven moisture in the forest steppe of Ukraine. Methods. During 2021–2023, three varieties of amaranth and MaxiMarin brand absorbent in the form of granules were studied in the field (Uman, 48°46¢N, 30°14¢E) at an application rate of 25 kg/ha. The varieties were evaluated according to the following parameters: weight of leaves, inflorescence and roots, yield of green mass in the flowering and full maturity phases. Amaranth grain yield, protein, fat and starch content were also determined. The methods of analysis of variance and correlation were used. Results. The absorbent applied had a significant effect on the productivity indicators, which were characterized by a significant difference between varieties. In particular, the average increase in the mass of leaves per plant for the studied varieties of amaranth was 12.2%, the mass of inflorescence – 8.9%, or 3.6 g/plant. The variety ‘Kharkivskyi­1’ responded best to the introduction of an absorbent that improved growth conditions, the weight of its inflorescence increased by 12.6%, or 5.3g/plant. The strengthening of growth processes was made possible by the improved deve­lopment of the root system and an increase in its mass, depending on the variety, of 12.3–24.6% (2.1–3.0 g/plant). At the same time, total plant weight increased by an average of 12.4% (11.2–13.3% in different varieties). Green mass yield increased by 13.6–16.5% (4.75–5.75 t/ha) due to the use of absorbent and was in the range of 33.0–40.0 t/ha. The highest values were characterized by the variety ‘Sem’ – 34.3 t/ha
in the control and 40.0 t/ha in the experiments with added absorbent. Its application also caused an increase in the yield of different varieties of amaranth by 0.30–0.38 t/ha or 16.0–18.3% (the most productive was the variety ‘Sem’ – 2.08 and 2.46 t/ha, depending on the variant of the experiment) and a significant decrease in the concentration of protein (by 0.1–10.0%), fats (by 7.4–19.5%) and starch (by 3.2–8.2%). Conclusions. Absorbents are an effective tool for levelling moisture imbalances and ensuring maximum realization of the productive potential of amaranth, but improving the water regime has a negative effect on the accumulation of protein, fats and starch.
Variety testing network of Ivano-Frankivsk region: historical origins and stages of formation
Authors: Melnyk S. I. , Sytnyk V.G. , Makarchuk B. M. , Boiko A.I. , Semysal A.V. , Sydorchuk A.I. , Pankiv V. I.
Published: December 2023

Purpose. To study the historical origins and stages of the formation of the variety testing network of the Ivano-Frankivsk Region, where one of the branches of the Ukrainian Institute for Plant Variety Examination is located.
Methods. The research used general scientific methods, in particular hypothesis, observation, historical methods with elements of extrapolation from the source scientific database, analysis, and the method of synthesis to draw conclusions.
Results. The varieties of plants common in the region meet the criteria of distinctness, homogeneity and stability generally accepted in international practice; they meet the needs of consumers in terms of economic and valuable properties; they do not pose a threat to the environment and human health. The variety testing network of the Ivano-Frankivsk Region was established in 1946 and its activities were coordinated by the Inspectorate of the State Commission for Variety Testing of Agricultural Crops in the Ivano-Frankivsk Region. In 2002, the Ivano-Frankivsk Regional State Centre for Expertise in Plant Varieties was established, which in 2012 became a branch of the Ukrainian Institute for Plant Variety Examination.
Conclusions. The formation of varietal plant resources in the Ivano-Frankivsk Region took place due to the rather long historical stages of formation and development of its varietal testing network.
Yield and grain quality of oat (Avena sativa L.) varieties grown on typical chernozems
Authors: Kalenska S. M. , Fediv R. V.
Published: December 2023

Purpose. To determine the yield potential and grain qua­lity of varieties of oat (Avena sativa L.) as a function of the nutritional and climatic conditions.
Methods. Field, laboratory (grain quality determination) and statistical methods were used in the research.
Results. Using different fertilization systems, seven oat varieties were studied, of which the most productive were ‘Ayvori’, ‘Lehin Nosivskyi’ and ‘Zakat’. The greatest increase in yield due to the use of fertilizers in 2022–2023 (1.24–2.73 t/ha with average increases of 0.32–2.83 t/ha) was observed for the cultivation of the ‘Ayvori’ variety. Additional increases due to the introduction of sulphur, compared to the options where only nitrogen, phosphorus and potassium were used, were observed for the varieties ‘Neptun’ – 0. 26–0.39 t/ha; ‘Lehin Nosivskyi’ – 0.47–0.49; ‘Svitanok’ – 0.23–0.66; ‘Zakat’ – 0.39–0.64; ‘Zubr’ – 0.41–0.54; ‘Albatros’ – 0.58–0.78; ‘Ayvori’ – 0.34–0.66 t/ha. The average yield of the control varieties in 2021–2023 was as follows 2.28 t/ha – ‘Neptun’; 2.64 – ‘Lehin Nosivskyi’; 2.50 – ‘Svitanok’; 2.70 – ‘Zakat’; 2.71 – ‘Zubr’; 2.60 – ‘Albatros’; 2.81 t/ha – ‘Ayvori’. Increasing the rate of nutrient application to the soil helped to improve grain quality. Thus, with the addition of N30P30K30 + N30 BBCH32, the protein content in the grain was within 10.2–10.8%; N60P60K60 + N30 ВВСН32 – 10.4–11.2; N90P90K90 + N30 ВВСН32 – 11.0–11.8; N120P120K120 + N30 BBCH32 – 11.4–12.4%. The addition of sulphur to the fertilization system resulted in a more efficient use of nitrogen and therefore an increase in the protein content of the grain of 1.3–1.8% compared to the options where the rate of macronutrients was the same for all varieties. The content of albumins and globulins was higher in the grain of the control variant (17.0–19.3 and 20.1–21.6% respectively) and did not vary significantly between varieties. The amount of reserve proteins – prolamins and glutelins – increased (from 28.4–30.2 to 34.8–36.2%) with an increase in fertilizer rate, especially with the introduction of N120P120K120S45 + N30.
Conclusions. All investigated oat varieties are highly productive and give yields in the range of 3.33–5.54 t/ha, depending on the fertilizer rate. The variety ‘Neptun’ is slightly lower in yield than the others, but has grain with a significant content of biologically valuable protein fractions. The application of sulphur­containing fertilizers increases yield, improves grain quality and allows a more efficient use of nitrogen, which makes it possible to reduce the basic rate of addition of macronutrients to the soil.
Types of Participants in Administrative Proceedings
Authors: Shkolyk Andriy
Published: December 2023

The paper attempts a critical analysis of the new norms of the Law of Ukraine "On Administrative Procedure", dedicated to the types of participants in administrative proceedings. The relevance of the study is due to the provision of a deeper understanding by the authorized subjects of law enforcement, which will be presented for the first time in a numeral administrative proceeding. At the same time, the article is aimed not only at a deepening of the understanding of new legal categories that have were included to participants in administrative proceedings by national legislator. Also, the expediency of their inclusion to participants is analyzed as well as possible of options for future improvement of the relevant norms of the Law of Ukraine "On Administrative Procedure" are proposed. For this, the comparative legal method is widely used in the analysis, which allows to investigate the origins and prerequisites for the selection of certain types of participants based on European administrative standards and the achievements of foreign legal doctrine, enshrined in the relevant legislative administrative procedure acts. As a result of the conducted analysis, it is recommended to change the concepts applied in the Ukrainian Law in the part of the entities that participate in the general administrative procedure almost completely. At the same time, it is recommended to do this not hastily, but only after the future professional commitment and the initial experience of its enforcement gained in the first period after the entry into force of the Law of Ukraine "On Administrative Procedure".