bluuebunny/crossref_metadata_2025 huggingface dataset:
El General Francisco Franco’s “The Power of Beliefs”
Authors: Rodríguez Barrueta Nydia Paola
Published: October 2022

This study analyzes and shows the elements of Francisco Francos’ various speeches and manner in which he targeted people's beliefs and conduct. His prime targets were the higher education organizations, educators and college students. Franco believed they needed to be indoctrinated in order to eradicate the republican beliefs from the previous Spanish administration. Thus he directed his propaganda towards them. His yearning to reach out to teachers and students was evident in Discurso pronunciado por S.E. El Generalísimo Franco, Jefe del Estado Español con motivo de la inauguración del presente curso escolar y de la Ciudad Universitaria de Madrid. The totalitarian vocabulary of the text comprises a utopian vision of reality and covert techniques of persuasion as well as control that, when combined, provided a potent weapon of manipulation. Taking into account both the era’s historical setting and the current political climate, this critical discourse analysis of the speech selected incorporates Wodak’s historical discourse approach with other approaches to analyze topoi in critical discourse. We see in the findings of this article how the combinations of a charismatic leader and power of speech play an important role in obtaining support of the population, even when it is against their own personal interest and well-being.
Reimagining Woman and Nature Beyond Dualism in Ann Jellicoe’s The Rising Generation
Authors: ŞAHİN GÜLTER Işıl
Published: October 2022

Ecofeminist philosophy has developed sophisticated critiques of the structures in western patriarchal culture that contribute to the continuing domination and oppression, not only of women but of nature as well. Drawing on ecofeminism’s critique of dualist structures as its principle guiding paradigm, this paper aims to explore how Ann Jellicoe comes to terms with the anti-dualist insights of ecological feminism in The Rising Generation (1969). The central issues that occupy and motivate ecofeminists, including the domination of women by men and humanity’s misappropriation of nature, are also Jellicoe’s primary concerns in the play. Jellicoe endeavors to depict characters and settings in a manner that rejects dualisms and embraces multiplicity, offering the basic conditions required for alternative representations of all the categories concerned, ‘woman,’ ‘man,’ ‘nature,’ and ‘culture’. In doing so, Jellicoe reconceptualizes the female/male and nature/culture relationships in configurations other than the traditional oppositions produced by the dualist strategy. In light of those preliminary observations, this paper indicates that in The Rising Generation, Jellicoe adopts an anti-dualist strategy to promote an egalitarian and pluralistic point of view through which all oppressive forms of domination within a culture can be unlocked.
Disfigural Dynamisms of the Pictographic Theater: Towards a Deleuzian Phenomenology of the Embodied Comics Experience
Authors: SHORES Corry
Published: October 2022

Vivian Sobchack’s Merleau-Pontian phenomenology of embodied film experience is applicable, with certain modifications, to the embodied comics experience, especially when considering her analyses of Gestalt closure, bodily affectivity, and synaesthesia. We adopt these concepts yet with a different aim, namely, to account for shocking, disorienting, and decompositional embodied comics experiences of dramatically deformed bodies. For this task, we employ Gilles Deleuze’s philosophy of shocking sensations and their role in promoting the “body without organs.” While it can be depicted in comics, like it is in Francis Bacon’s paintings, the visual experience of such a figure may also communicate these disordering forces to the viewing reader’s body as well, thereby shockingly disrupting their own inner workings. We test the potential applicability of these Deleuzian concepts by examining deformational bodies in Peter Bagge, Mary Fleener, and Craig Thompson, which will demonstrate the potential aptness of a Deleuze-inspired analysis of physiological shocks in the comics experience.
МЕТОДОЛОГІЧНІ ОСНОВИ ДОСЛІДЖЕННЯ ДУХОВНОГО ПОТЕНЦІАЛУ ТЕРИТОРІАЛЬНИХ ГРОМАД: ТЕРМІНОЛОГІЯ
Authors: Дороніна Майя Степанівна , Іванова Ольга Юріївна , Доронін Андрій Віталійович
Published: October 2022

Economic instability, increasing social problems, uncertainty of economic guidelines for the development of Ukraine indicate the need to review the problems and prospects for the development of economic science and practice. The purpose of the article is to determine the content of the main terms in the study of the spiritual potential of territorial communities. The main hypothesis of the study was the assumption that clarifying the essence and content of the terminology of the subject area of the study will provide constructive discussions regarding the definition of the main problems and prospects for its development. Presenting main material. The loss of controllability of the development of the spiritual potential of territorial communities requires a review of the technologies of its research based on methodological pluralism, focused on determining the possibilities of transforming an economy focused on the production of goods into an economy of expanded reproduction of potential human abilities to respond to the increase in non-traditional situations in life. Originality and practical significance of the research. The effectiveness of such a reaction depends on the managers' ability to diagnose the spiritual potential of subordinates, activate their desire to generate unique ideas for overcoming crises. Conclusions and prospects for further research. The effectiveness of using the spiritual potential of territorial communities depends on the constructive dialogue of the parties interested in its development. The initial stage of the dialogue should be to agree on the essence and content of the main terms. In further research, it is necessary to focus attention on the definition of such methodological constructions as a detailed analysis of unique situations, culturodigm, diagnostic technology of personal and collective spiritual potentials of members of the territorial community.
ЕКСТЕРНАЛІЇ УПРАВЛІННЯ РЕФЛЕКСІЄЮ ФІНАНСОВОЇ ТА СОЦІАЛЬНО-ЕКОНОМІЧНОЇ СИСТЕМ
Authors: Ліхоносова Ганна Сергіївна
Published: October 2022

In connection with the growth of innovation management positions, the need to master reflexive methods of introducing innovations into financial and complex socio-economic systems acquires a characteristic role, especially in strategic periods. It was established that in today's turbulent economic conditions, the development of externalities of their management is a prerequisite for the effective functioning of financial and socio-economic systems. The purpose of the article is to identify visible and invisible principles of externality of reflection management of financial and socio-economic systems and to determine the level of readiness of elements of financial and socio-economic systems for the process of innovation. The subject of the study is modern trends in the spread of financial tension, changes in the financial-economic and socio-economic systems, new threats to the spread of externalities of reflection management. The hypothesis of the research is the influence of the consequences of financial and economic deformations on the trends of modifications of the externalities of reflection management at different levels. Methods used in the research: comparison, comparison, systematic and analytical approaches, generalization and classification, dialectical and formal logic. Presenting main material. It was determined that the resource component of innovative reflection is the basis for determining the degree of readiness of the financial and socio-economic systems for the implementation of innovativeness and the formation of strategic management decisions. Approbation and verification of the obtained theoretical conclusions was carried out by conducting a survey of a certain circle of respondents from among the expert environment and the environment of practicing specialists. The main characteristics of the management of innovative reflection of socio-economic systems are revealed: the effectiveness of methods of innovative reflection, the degree of importance of types and forms of reflection for innovative activity, the influence of barriers on the implementation of innovative reflection, the influence of factors on the effectiveness of management of innovative reflection, the influence of the ability to reflect on the success of innovative activity The originality and practical significance of the obtained results lies in the possibility of applying the provided recommendations to improve management and financial control procedures, improve the efficiency of business processes of economic entities in modern conditions. Conclusions. The management of the reflection of financial and socio-economic systems is a multi-level complex of successive management decisions regarding the transformation of management externalities, the formation of an analytical basis for evaluating the reflection of financial and socio-economic systems in order to implement the parameterization of self-development mechanisms of socio-economic systems.
РОЛЬ УПРАВЛІННЯ КЛАСТЕРАМИ У РОЗВИТКУ ЕКОНОМІКИ КАЗАХСТАНУ
Authors: Бідельманова Мадіна Майданівна
Published: October 2022

The priority task is to ensure a sustainable competitive national economy based on the introduction of advanced technologies, ecologically clean, safe production, product quality management systems, and resource conservation systems. The purpose of the article is to reveal the approach to the formation of regional industrial policy based on the creation of cluster schemes on the example of automobile manufacturing in the East Kazakhstan region. The methodological basis of the research was logical methods of information processing, methods of system analysis, abstract-logical method for formulating conclusions. The main research hypothesis is that clusters should unite geographically close groups of interdependent companies. The co-location of firms contributes to the formation and enhancement of value-creating advantages resulting from a network of interactions between firms. Presenting main material. The article reveals the prospects of the cluster organization of the national economy of Kazakhstan, the essence and structure of the cluster. Based on the results of the analysis of indicators of socio-economic development of the East Kazakhstan region, the prerequisites for the creation of an automotive cluster have been determined. Originality and practical significance of the research. Indicators of socio-economic development of the East Kazakhstan region allowed it to be used as a platform for the development of an automotive cluster. The supply of Kazakh cars to the countries of Central Asia and Transcaucasia can bring the country more than $1 billion in additional export revenue per year. Conclusions and prospects for further research. At this stage, the problem of ensuring sustainable growth of the economy of the Republic of Kazakhstan by increasing the competitiveness of its industrial products at the world, national and regional levels becomes paramount. Economic science faces the task of developing an industrial policy mechanism, the main goals of which are to ensure sustainable growth rates and increase competitiveness.
АНАЛІЗ ПРИВАБЛИВОСТІ ВІДНОВЛЮВАНОЇ ЕНЕРГЕТИКИ В ОКРЕМИХ КРАЇНАХ
Authors: Корогодова Олена Олександрівна , Черненко Наталя Олександрівна , Моісеєнко Тетяна Євгенівна , Глущенко Ярослава Іванівна
Published: October 2022

The increasing importance of crises, such as the crisis caused by russia's invasion of Ukraine, has a significant impact on the formulation of policies for energy development in this area and the use of renewable energy sources. This issue is especially relevant for states that depend on energy supplies from other countries or have transit flows of resources on their territory. This article aims to analyze the experience of individual countries concerning the development of renewable energy and determine future directions and practical recommendations for Ukraine's development of green energy. Subject of study. The subject of the study is the process of transformation of energy policy based on the use of alternative energy sources in different regions of the world. The methodological basis and information base of the research are legislative and regulatory documentation, current scientific and applied research, and statistical information. The article uses a number of methods, including analysis, synthesis, comparison and generalization. Socio-economic processes of renewable energy policy formation were studied in dynamics. A tabular format is used to compile the data to improve clarity. Also, the research was conducted in accordance with the features of the system approach and structural-functional analysis. The hypothesis of the study dealt with the possibility of using the experience of obtaining significant results in the development of renewable energy in certain parts of the world to develop the appropriate policy in Ukraine. Presenting main material. Groups of countries with the existing potential of solar, wind and hydrogen energy, and a separate group of countries that, due to climatic conditions and economic opportunities, can implement several types of alternative energy, are highlighted. In terms of the beginning of military activities and the destruction of a significant part of the energy infrastructure, Ukraine has to assist in the development of alternative energy sources such as wind, water and solar power. The originality and practical significance of the study is due to the analysis of the development processes of renewable energy, taking into account the characteristics of different countries. Research conducted and practical recommendations developed provide an opportunity to contribute to the formulation of policy for development of the Ukrainian economy during this period of crisis and post-crisis. Conclusions. Among the studied world leaders in the implementation of renewable energy, groups of countries with the existing potential of solar, wind and hydrogen energy, and a group of countries that, due to climatic conditions and economic opportunities, can implement several types of alternative energy should be singled out.
Development of “No Anemia No Stunting” (Si NaNing) Modules and Application in Efforts to Prevent Stunting in Archipelago Regions
Authors: Aminin Fidyah , Kristianto Jusuf , Rianda Dewi Puspa , Haryadi Haryadi , Cintiani Jeni Cesi
Published: October 2022

The average prevalence of stunting toddlers in Indonesia from 2005 to 2017 is 36.4%. Incidence of stunting toddlers (short) is a major nutritional problem faced by Indonesia. Stunting cases in the Riau Islands reached 24 percent of the number of babies born in 2018. One of the causes of stunting is the lack of nutrients fulfilment during pregnancy, including anemia in pregnancy. Currently, there is no media module and application for stunting prevention health promotion. The purpose of the study was to determine the effectiveness of the "No Anemia No Stunting" (Si NaNing) application and the Si NaNing Module on stunting prevention. The study was conducted in Tanjungpinang City in May-November 2020. The research design was quasi-experimental with pre-posttest with control group design. The instrument used is a structured questionnaire. Data collection is during the pre test and post test. The population is all pregnant women in Tanjungpinang City. The sample is 30 respondents/pregnant women from Independent Practice of Midwives in Tanjungpinang City. Data analysis used Dependent T Test for the intervention group (application) and Wilcoxon for the control group (module). The results showed that there was a significant difference in knowledge (p value 0.001), attitude (p value 0.001), and motivation (p value 0.001) in pregnant women before and after being given health education using the Si NaNing application. Meanwhile, in the module group, only motivation (p value 0.000) had a significant difference.
Plantas Nativas da Medicina Tradicional Brasileira: Uso Atual e Necessidade de Proteção
Authors: Brandão M. G. L. , Gomes C. G. , Nascimento A. M.
Published: October 2022

Apesar do secular emprego de muitas plantas nativas na medicina tradicional, raros são os exemplos de produtos registrados no Brasil com essas espécies. Neste estudo, são apresentados dados históricos e atuais sobre 23 plantas medicinais nativas do Brasil, usadas na medicina tradicional de Minas Gerais e inscritas na Farmacopéia Brasileira. O estudo mostra o quanto as empresas brasileiras e as dos demais países ricos em biodiversidade têm investido pouco no desenvolvimento e patenteamento de produtos da sua própria flora medicinal, confirmando a necessidade de estímulos à validação e proteção dessas plantas.
Education of Fish Detection Tools (Fish Finder) to Fishermen in Dusun XI Percut Sei Tuan Village, Deli Serdang Regency
Authors: Manurung Vindy Rilani , Khairunnisa  , Siregar Rizky Febriansyah , Dewinta Astrid Fauziah , Hasibuan Julia Syahriani
Published: October 2022

Traditional fishermen in Dusun XI, Percut Village, Deli Serdang Regency, North Sumatra Province, using rawai fishing gear, nets, and hand line instead of other technological gear. Sea tides also influence fisherman's ability to get out of sea; when the river mouth reaches high tides, fishermen will go to sea; when the river mouth recedes, fishermen can not go to sea. Fishermen are frequently returned to sea with little results, especially in the absence of technological application. Education is important, and advances in fish finder technology can help fishermen catch more fish by making it easier to use. The implementation method is theoretical and practical, with the formation of an actually trying to implement committee team occurrence through educational methods with theoretical media attention, as well as practical activities such as fisherman group discussions and joint operation demonstration activities in the field. Fishermen in Dusun XI, Percut Village, Deli Serdang Regency benefit significantly from using a fishfinder tool and helping in increasing fish catches, according to data monitoring and assessment.
Growth and Development Factors of Infants and Maternal Conditions During Pregnancy for the Eruption of the First Deciduous Teeth (Literature Review)
Authors: Ginting Rehulina , Tarigan Yesica Elisabeth
Published: October 2022

Tooth eruption is a condition in which the cusp or incisal of the tooth emerges through the gingiva, but not exceeding 3mm above this level after the corona is formed. The first human tooth that erupts is the mandibular primary central incisor, which is the reference for the eruption of others, including the primary and permanent teeth, that support the growth of the jaw, face, mastication, swallowing, speech, and aesthetics. Furthermore, tooth eruption is influenced by the growth and development of the fetus during pregnancy. Maternal conditions during pregnancy such as age, level of education, physical condition, and nutritional intake affect fetal nutrition which indicates the level of growth and development in the form of head circumference, birth weight, and height that affect the eruption time of the mandibular deciduous central incisor. During pregnancy, the maternal preparation to be considered is the age which might range from 20-35 years, adequate nutritional intake of carbohydrates, folic acid, protein, vitamin C, vitamin D, and minerals, prevention of physical fatigue, intelligence in choosing nutrition, and abstaining from alcohol and caffeine consumption. This study aims to provide information/education on the preparation of pregnant women for the eruption of the mandibular primary central incisor which is part of the infant's growth and development.
Hyaluronic Acid And Its Role In Periodontal Healing
Authors: Wulandari Pitu , Amalia Martina , Budi  , Simanjuntak Rio , Satria Denny
Published: October 2022

Hyaluronic acid is known as hyaluronan or hyaluronate, which has the function of increasing the mediator of periodontal regeneration. Hyaluronate acid has many roles in the early stages of inflammation, such as providing a structural framework through the interaction of hyaluronate with fibrin clots that modulate host inflammation and infiltration of the extracellular matrix of cells at the wound site so that this material becomes a therapeutic material used in various fields, especially in the field of periodontics. All periodontal tissues have shown the presence of hyaluronate, which is specifically concentrated in non-mineral tissues such as gingiva and periodontal ligament, which affects the growth, development, and repair of tissues in periodontal disease. The role of hyaluronic acid in periodontal healing will be discussed in this article.
Relationship of the soil chemical properties (pH, C-Organic And Cec) to the production of potato (Solanum Tuberosum L.)at Karo District
Authors: Evandra Naufal , Razali  , Damanik M. Madjid
Published: October 2022

The research aims to determine the relationship of soil chemical properties (pH, C-organic, and Cation exchange capacity) to the productivity of potato in Karo Regency. The research was started from June till August 2021. The research was conducted using a survey method and soil sampling conducted by stratified random sampling technique (low-high productivity). The 32 samples were taken of 5 sub-districts (Berastagi, Merdeka, Kabanjahe, Tigapanah, Simpangempat) in Karo Regency. Regression tests were performed using the SPSS (Statistical Package for the Social Sciences) version 25 program to obtain the relationship between the soil chemical properties and the productivity of potato (Solanum tuberosum L.). On results research shows that the chemical properties of the soil (pH, C-organic and CEC) simultaneously affected potato productivity by 24.9%. Partially, soil pH has an influence and is correlated with potato (Solanum tuberosum L.) productivity.
The Relationship Of The Land Physical Characteristic To The Productivity Of Potato (Solanum Tuberosum L.) At Karo Regency
Authors: Nabilla Putri Aninda  , Razali  , Supriadi
Published: October 2022

The research aims to determine the relationship’s of the lands’s physical characteristic (temperature, soil texture, soil moisture, slope, and planting direction) to the productivity of potato (Solanum tuberosum L.) at Karo Regency. The research was started from June 2021 to August 2021. This research was conducted using a survey method at 5 sub-districts (Berastagi, Merdeka, Kabanjahe, Tigapanah, Simpangempat) at Karo Regency using Stratified random sampling with potato productivity (low-high productivity) as consideration. The results showed that the physical characteristic of land (temperature, soil texture, soil moisture, slope, and planting direction) simultaneously affected potato productivity, 51% of potato productivity were affected by the characteristics of the land. Partially: temperature, slope, and soil moisture affect the potato productivity. Temperature and slope were positively correlated with potato productivity.
First record of Syrphophilus bizonarius (Gravenhorst, 1829) (Hymenoptera, Ichneumonidae, Diplazontinae) from Algeria
Authors: Ait Amar S. , Benoufella–Kitous K. , Medjdoub–Bensaad F. , AlHussain Kareem A. A.
Published: October 2022

The subfamily Diplazontinae (Hymenoptera, Ichneumonidae) has been little studied in Algeria. Following our study in the region of Tizi–Ouzou from March to May 2020, we report the presence of the species Syrphophilus bizonarius (Gravenhorst, 1829) for the first time in this country, starting from a single male individual that emerged from a hoverfly pupa of Episyrphus balteatus (De Geer, 1776) (Diptera, Syrphidae, Syrphinae).
E-Marketing of Agriculture Commodities: Challenges and Prospects for Marginal and Small Farmers in India
Authors: Jena Damodar , Mohapatra Debasish , Pani et. al. Saswat Kumar
Published: October 2022

The existing agricultural market system borne operational inefficiency and is challenged with several problems which marginal and small farmers face. Due to a lack of infrastructure, storage capacity, connectivity, and alternatives to sell produce at a fair price, the government of India tried to connect farmers across the country through an electronic platform i.e. E-NAM in 2016. Prior to the government intervention in the electronic-platform domain, several Private initiatives have been taken through a business model such as ITCe-choupal, Ninjacart, and a few others. The electronic trading platform is an attempt to transform the market system. Rural producers need to connect with consumers and traders. The paper is based on two research questions: a) what is the state of e-marketing in India and Odisha and grey area if any?; b) What are the challenges and prospects of e-marketing in agriculture faced by marginal and small farmers? The paper has adopted a descriptive approach by reviewing the existing literatures, secondary reports, policy documents, and case studies. It was found that strengthening the institutional governance, bring innovation, and adopting risk among the farmers are the key important bases for the success of the institutions. It was also observed that lack of participation and awareness among the farmers, and lack of extension remains a bottleneck for the success of marketing institutions. The existence of E-NAM is at a nascent stage and it needs strong stakeholder support to function effectively.
Quantitative ultrasound radiomics in predicting response to neoadjuvant chemotherapy in patients with locally advanced breast cancer: Results from multi-institutional study
Authors: DiCenzo Daniel , Quiaoit Karina , Fatima Kashuf , Bhardwaj Divya , Sannachi Lakshmanan , Gangeh Mehrdad , Sadeghi-Naini Ali , Dasgupta Archya , Kolios Michael , Trudeau Maureen , Gandhi Sonal , Eisen Andrea , Wright Frances , Hong Nichole Look , Sahgal Arjun , Stanisz Greg , Brezden Christine , Dinniwell Robert , Tran William T. , Yang Wei , Curpen Belinda , Czarnota Gregory  J.
Published: October 2022

Background: This study was conducted in order to develop a model for predicting response to neoadjuvant chemotherapy (NAC) in patients with locally advanced breast cancer (LABC) using pretreatment quantitative ultrasound (QUS) radiomics. 

Methods: This was a multicenter study involving four sites across North America, and appropriate approval was obtained from the individual ethics committees. Eighty-two patients with LABC were included for final analysis. Primary tumors were scanned using a clinical ultrasound system before NAC was started. The tumors were contoured, and radiofrequency data were acquired and processed from whole tumor regions of interest. QUS spectral parameters were derived from the normalized power spectrum, and texture analysis was performed based on six QUS features using a gray level co-occurrence matrix. Patients were divided into responder or nonresponder classes based on their clinical-pathological response. Classification analysis was performed using machine learning algorithms, which were trained to optimize classification accuracy. Cross-validation was performed using a leave-one-out crossvalidation method. 

Results: Based on the clinical outcomes of NAC treatment, there were 48 responders and 34 nonresponders. A K-nearest neighbors (K-NN) approach resulted in the best classifier performance, with a sensitivity of 91%, a specificity of 83%, and an accuracy of 87%. 

Conclusion: QUS-based radiomics can predict response to NAC based on pretreatment features with acceptable accuracy.
Ethical, Stigma, and Policy Implications of Food Addiction: A Scoping Review
Authors: Cassin Stephanie , Buchman Daniel Z , Leung Samantha E. , Kantarovich Karin , Hawa Aceel Christina , Carter Adrian , Sockalingam Sanjeev
Published: October 2022

    

The concept of food addiction has generated much controversy. In comparison to research examining the construct of food addiction and its validity, relatively little research has examined the broader implications of food addiction. The purpose of the current scoping review was to examine the potential ethical, stigma, and health policy implications of food addiction. Major themes were identified in the literature, and extensive overlap was identified between several of the themes. Ethics sub-themes related primarily to individual responsibility and included: (i) personal control, will power, and choice; and (ii) blame and weight bias. Stigma sub-themes included: (i) the impact on self-stigma and stigma from others, (ii) the differential impact of substance use disorder versus behavioral addiction on stigma, and (iii) the additive stigma of addiction plus obesity and/or eating disorder. Policy implications were broadly derived from comparisons to the tobacco industry and focused on addictive foods as opposed to food addiction. This scoping review underscored the need for increased awareness of food addiction and the role of the food industry, empirical research to identify specific hyperpalatable food substances, and policy interventions that are not simply extrapolated from tobacco. 
Antioxidative effect of metformin on valproic acid induced hepatoxicity in male rats
Authors: Intesar Tarik Numan  , Nadia Hameed Mohamed  , Zainab Khalid Ali
Published: October 2022

Metformin is 1,1-dimethylbiguanide hydrochloride, is the first-line therapy for type 2 diabetes. Additionally, several studies focused on the role of metformin in antioxidant activities for the treatment of hepatic disorders. The experimentally

 

 -based result on valproic acid's liver injury, a front-line medicine for the treatment of epilepsy, attracted a lot of interest. As a result, the effect of metformin on valproic acid-induced redox disturbances in rat hepatic tissue was studied. metformin at 250 mg/kg dose was administered via oral gavage for 30 days, and valproic acid at a dose of 400 mg/kg was administered by intraperitoneal route starting from the twenty-second day of the experiment, for eight days to induce hepatotoxicity. Treatment with metformin reduced valproic acid-enhancing alanine aminotransferase, aspartate aminotransferase activities. Tissue levels of malondialdehyde in the liver tissue of valproic acid-treated rats significantly increased (P-value < 0.05) whereas glutathione decreased. The coadministration of metformin with valproic acid significantly decreased the malondialdehyde levels and increased glutathione levels (P-value < 0.05). Finally, metformin protected rats from valproic acid-induced hepatotoxicity, improved antioxidant status, and reduced hepatic oxidative stress.
Evaluating the Reliability of MM-PB/GB-SA Method for the Protein-Ligand Binding Free Energies Using Penicillopepsin-Inhibitor ligands
Authors: Twana Salih
Published: October 2022

An accurate prediction of the ligand-receptor binding free energies (ΔG) is a critical step in the early stages of rational drug design. The Molecular Mechanics-Generalized Born Surface Area (MM-GBSA) method is a popular

 

approach to estimate ΔG. However, correlations between the predicted and the experimental ΔG are variable. The goal of this study is to investigate various approaches to optimize accuracy of the MM-GBSA method. A molecular dynamic (MD) simulations protocol was applied using penicillopepsin receptor against its inhibitor ligands, repeated 50 times for each complex system. After that, ΔG of the five inhibitors were predicted using MM-GBSA method. Moreover, a diverse ΔG values were calculated from the replicate MD simulations of each system. The results were showed correlations not only between the predicted and the experimental binding affinities of the systems but also between the predicted values and root-mean-square deviation. In addition, statistical analysis was evaluated the sample size.
Degitalization of Medical Record Administration Services at Dian Rapha Medika Toraja Clinic
Authors: Hirman  , Nahiruddin  , Imasita  , Nahlah  , Gunawan Andi
Published: October 2022

In the world of health, the management of administrative documents, especially medical records, is a very important thing to do. Management of medical records in collaboration with information technology can improve services effectively and efficiently in managing information data quickly and avoiding delays in service. Until now, the Dian Rapha Medika Toraja Clinic still uses manual medical record administration management with several existing obstacles. This causes health services that should be handled quickly cannot be carried out. Therefore, the researcher is interested and aims to design a website-based medical record administration management system at the Dian Rapha Medika Clinic Toraja. This study uses the waterfall model design method, which consists of 1) Needs Analysis, 2) System Design, 3) Implementation, and 4) Testing. The data collection techniques in this design are 1) Interview and 2) Observation. The results of this study indicate several advantages when using digitization of administrative services for medical colleagues at Dian Rapha Medika Toraja clinic, namely: 1) assisting in digitally documenting patient medical record data; 2) input of patient medical record data is easier and faster; 3) facilitate doctors in analyzing the patient's medical records; 4) searching for patient medical record data is easier and faster; 5) storage of medical record data is more concise and well-structured due to the integration of patient data and medical records so that it can accelerate administrative management at the clinic.
Impacts of Covid-19 on Migrants and Refugees
Authors: Baitha Subhash Kumar , Tyagi Rinkal , Chatterjee Souvik
Published: October 2022

Since the 1970s, in the aftermath of new social movements, the concept of refugees and migration in international politics has dominated both the academic discipline and public debates. According to the United Nations High Commissioner for Refugees, more than 82.4 million people worldwide were forcibly displaced from their homes by the end of 2020, either as internally displaced persons (IDPs) or as refugees, as a result of violent conflict, persecution, famine, or natural disasters. Even in normal times, the lives of refugees and migrants are fraught with difficulties, but in the midst of an  pandemic like Covid-19, this problem has taken on new dimensions. The only way to avoid the pandemic is to take precautions and maintain a safe distance from one another. These precautions are extremely difficult for refugees and migrants to take amidst a global pandemic. Keeping in mind the international efforts and the problems faced by refugees and migrants, this paper is an attempt to comprehend the challenges faced by refugees and migrants during Covid-19 and what global efforts have been made to mitigate the pandemic's impact on refugee and migrant life.
ON THE SPECIFICITY OF THE OBLIGATIONS OF THE PARTIES TO NEIGHBORHOOD LEGAL RELATIONS
Authors: АМИНЕВА Айгуль Юлаевна
Published: October 2022

The existence of good neighborhood relations is based on the scrupulous performance by each of the parties of their obligations, which ultimately results in the observance of an order based on law.Purpose: to analyze the problems of legal regulation of the  bligations of the parties to neighborhood legal relations, their characteristics and content. In the course of the study, general scientific and specificscientific (legal and dogmatic, interpretation of legal norms, and others) research methods are used. Results: it is established that, to date, there is no legal definition of the obligations of neighbors,the obligations of the parties to neighborhood legal relations are separately enshrined in various normative acts, including in sources of public branches of law. It is concluded that an obligation of a partyin neighborhood legal relations should be understood as a measure of proper behavior of one person (neighbor) established by law, agreement of the parties or custom in order to satisfy the interestsof another person (another neighbor), provided with the possibility of applying coercive measures. The main purpose of fulfilling civil law obligations of the neighbors is to ensure the observance of the rightsand legal interests of the parties to neighborhood legal relations, in which the conduct of each party to this legal relationship will not exceed the permissible limits, established by law, including sanitary,urban planning, building, technical regulations and standards, either by any agreement of the parties or by customs in force in a particular t erritory.
FORWARDING ACTIVITIES IN THE FIELD OF POSTAL SERVICES
Authors: САПЕГА Вячеслав Александрович
Published: October 2022

Currently, there is no scientific justification for the legal nature of postal forwarding services, despite the fact that their existence is reflected in Article 1 of the Federal Law of June 30, 2003 No. 87-FZ «On Forwarding Activities». There are no unanimous opinions on the correlation of postal services with forwarding, regulated by the rules of Ch. 41 of the Civil Code of the Russian Federation. This constrains the development of legislation in this area of legal regulation and relevant segments of transport and communication markets. Purpose: to develop a scientific idea of the bases of legal regulation of forwarding activities in the field of postal services. Methods: empirical methods of comparison, description, interpretation; theoretical methods of formal and dialectical logic; specific scientific methods: legal modeling, legal-dogmatic and interpretation of legal norms. Results: the article proposes solutions to the problem of the correlation of postal services with forwarding activities. It is proved that at present there is no distinction between these types of services, especially in the case of sending parcels. It is proved that sending parcels cannot be a communication service because there is no information component necessary for communication. It is proposed to consider services related to the delivery of parcels as forwarding services in the field of postal communications. It is also proposed to legally distinguish this type of service and communication services and to formulate the generic concept of «postal service».
SUBJECTS OF RESEARCH ACTIVITIES: FROM TRADITIONAL CONCEPTS TO CIVIL SCIENCE
Authors: СЕРОВА Ольга Александровна
Published: October 2022

Scientific and technological development of the country is one of the key tasks of the Russian Federation. Competitiveness in the global market for high-tech and knowledge-intensive products needs to be improved. That national objective can not be achieved without legal institutions capable of regulating that relationship. The issue of legal personality is topical and of considerable practical importance in the context of new technological challenges. Purpose: to determine the characteristics of the legal status of subjects involved in research activities. Methods: the author applies theoretical methods of formal and dialectical logic; empirical methods of description and interpretation; as well as specific scientific methods: juridical-dogmatic and interpretation of legal norms. Results: the main forms of research activities are identified, including the description of the phenomenon of «civil science». The requirements to subjects carrying out research activities, features of their legal status are determined. The distinguishing features of civil science are identified as a phenomenon that is not legally enshrined in Russian law.
MODIFICATION OF THE ELECTORAL LEGISLATION IS THE IMPERATIVE OF OUR TIMES
Authors: МАЛЫЙ Александр Фёдорович , НИГМЕТЗЯНОВ Алмаз Альбертович
Published: October 2022

The article discusses the issues of modernization of the electoral legislation implemented in the last few years. The factors that caused the appearance of innovations and their content are considered. A significant role in this process was played by the political component, the increased confrontation between two approaches to understanding the future of Russia: strengthening state principles and following liberal ideas. Attention is focused on the innovations that appeared in the conditions of the pandemic. A brief summary of them is given. Purpose: to show the modification of the electoral legislation in Russia in connection with the political and epidemiological situation in the country, to demonstrate the possibility of solving current problems by reflecting them in the statutory legal regulation. Methods: the comparative method is used to compare the norms of electoral law. The method of formal logic allows to show the relationship of political and epidemiological components in the modification of electoral legislation. The formally legal method is applied in the process of evaluating the innovations of electoral law. The result of the study is that the legislator is obliged to take into account political, socio-economic, epidemiological conditions when forming the legal basis of elections. A popular vote is the only way to express the will of the people and to ensure that voters trust their representatives in the policies pursued by the authorities.
ON THE CLASSIFICATION OF RISK CONTRACTS AS SPECIAL CIVIL LAW STRUCTURES
Authors: Атнабаева Юлия Вилевна
Published: October 2022

The development of market relations is accompanied by an increase in the needs of participants in civil law relations for contractual forms that ensure the redistribution of risks. At the same time, the established list of legally enforceable contractual forms containing elements of a risk nature seems to be very flexible and does not meet the requirements of civil turnover. The main trend of reforming Russian civil legislation is the complication of both the system of risk contracts and their legal structure itself, in particular, new civil law constructions of risk contracts have emerged (a contract for compensation of losses, an option contract). These circumstances make it necessary to systematize them, to identify the features inherent in certain types of risk contracts. Purpose: comprehensive analysis and identification of signs of special civil law constructions of risk contracts, as well as the author's classification of risk contracts. Methods: general scientific and special research methods are used such as dialectical, comparative legal, formal logical, system analysis and synthesis. Results: the study helps to identify the multiplicity of classification criteria that can be reduced to two groups of grounds: general and special, on the basis of which special civil law constructions of risk contracts are distinguished.
DELEGATION OF POWERS WITHIN THE SYSTEM OF PUBLIC AUTHORITY
Authors: ПАШКОВА Татьяна Валерьевна
Published: October 2022

The relevance of the topic of the article is due to the amendments to the Constitution of the Russian Federation that entered into force on July 4, 2020, and enshrined, in particular, the principle of the unity of the system of public authority in the Russian Federation (Part 3 of Article 132). The amendments provide for the need to change the existing legislation and adopt normative acts regulating in more detail the relations within the unified system of public authority between its levels - federal, regional, municipal, as well as the implementation of the principle of the unity of the system of public authority, its impact on the mechanism for transferring powers between the levels of public authority. The purpose of this article is to analyze the current legislation and the relations that are developing in practice on the transfer of powers between the levels of public authority of the Russian Federation. Methods: analysis of legal regulation, formal legal, comparative legal. Results: the article identifies the components of the system of public authority in the Russian Federation, the mechanisms for the transfer of powers between the levels of public authority. It is revealed that the amendments to the Constitution of the Russian Federation and the legislation adopted in the development of their provisions have consolidated the relations existing in practice on the transfer of powers between the federal, regional and municipal levels.
ON THE ISSUE OF PROTECTING THE IMAGE OF A CITIZEN
Authors: БАЛЯКИНА Елена Борисовна
Published: October 2022

In 2006, Article 152.1, devoted to the protection of the image of a citizen was introduced into the Civil Code of the Russian Federation. This rule alone does not seem to be sufficient to fully and effectively address the problems associated with the use and protection of the image of a citizen. Active use of social networks facilitates the dissemination of photos containing the image of a citizen, including without his consent, as well as containing a modified image of the citizen, which may affect his honor, dignity, or violate his business reputation. Modern technology makes it easy to change the image of a citizen in photographs or videos, for example, by imposing a digital mask, the concept of which is not in Russian legislation. There is also no clear legal regulation of relations in which another person uses the image of a citizen, including for profit. Purpose: to conduct a comprehensive study of the problems of legal protection of the image of a citizen and the identification of problems of legal regulation of its use, the development of proposals for improving the legislation on the protection of the image of a citizen. Methods: dialectical method of cognition, comparative-legal, formal-legal, system-analytical, logical. Results: the author gives her definition of the digital mask and makes proposals for the protection of the image of a citizen when placing material on the Internet.