Hubungan antara Kadar Hemoglobin dan Jumlah Leukosit dengan Kejadian Prematuritas di Rumah Sakit Umum Pusat Dr. Hasan Sadikin Bandung
Authors: Saleh Idham Rizali , Mose Johanes C. , Handono Budi 
Published: March 2024

Tujuan: Untuk mengetahui adanya hubungan antara kadar hemoglobin dan kadar leukosit maternal dengan kejadian prematuritas di Rumah Sakit Umum Pendidikan Dr. Hasan Sadikin Bandung. Metode: Rancangan penelitian ini adalah observasional analitik dengan desain studi potong-lintang. Subjek penelitian adalah pasien dengan persalinan pada kehamilan usia 24–42 minggu di Rumah Sakit Umum Pendidikan Dr. Hasan Sadikin Bandung periode Januari – Desember 2019 yang berjumlah 82 pasien. Dilakukan pengumpulan data dari rekam medis pasien berupa usia kehamilan, kadar hemoglobin, kadar leukosit, dan faktor perancu berupa usia, tingkat pendidikan, dan tingkat paritas. Hubungan antara kadar hemoglobin dan jumlah leukosit dengan persalinan prematur dianalisis statistik dengan uji Chi-square. Variabel-variabel perancu akan dikendalikan melalui analisis multivariat dengan regresi logistik. Hasil: Terdapat hubungan yang signifikan antara kadar hemoglobin dan kadar leukosit dengan terjadinya persalinan prematur (p<0,05). Hasil analisis dengan uji regresi logstik menunjukkan bahwa tetap terdapat hubungan bermakna antara kadar hemoglobin (OR 0,27; p<0,05) dan kadar leukosit (OR 3,60; p<0,05) dengan persalinan prematur setelah dilakukan pengendalian faktor perancu. Kesimpulan: Kadar hemoglobin dan kadar leukosit memiliki hubungan yang signifikan dengan kejadian persalinan prematur tanpa dipengaruhi oleh usia, tingkat pendidikan, dan tingkat paritas. Associated Between Hemoglobin and Leukocytes Levels with the Incidence of Prematurity in Dr. Hasan Sadikin General Hospital BandungAbstract Objective: To examine whether an association exists between maternal hemoglobin and leukocyte level and the risk of preterm delivery in Rumah Sakit Umum Pendidikan Dr. Hasan Sadikin Bandung. Method: An analytical cross-sectional study involving 82 pregnant women who delivered at 24 – 42 weeks gestation at Rumah Sakit Umum Pendidikan Dr. Hasan Sadikin Bandung in January – December 2019 was conducted. Gestational age, maternal hemoglobin level, maternal leukocyte level, and confounding factors including age, education level, and parity data were collected from patients’ medical records. The association between maternal hemoglobin and leukocyte level with the risk of preterm delivery was analyzed using Chi-Square test. Multiple logistic regression models were used to control for confounding variables. Result: Maternal hemoglobin and leukocyte level were significantly associated with the risk of preterm delivery (p<0.05). Multiple logistic regression models showed that the associations between maternal hemoglobin level (OR 0.27; p<0.05) and maternal leukocyte level (OR 3.60; p<0.05) with the risk of preterm delivery were still significant after adjusting for confounding variables. Conclusion: Maternal hemoglobin and leukocyte level were significantly associated with the risk of preterm delivery after adjusting for age, education level, and parity. Key word: Hemoglobin, Prematuritas, Leukocyte.