bluuebunny/crossref_metadata_2025 huggingface dataset:
Marine algal flora of Graciosa Island, Azores
Authors: Neto Ana I. , Parente Manuela I. , Botelho Andrea Z. , Prestes Afonso C. L. , Resendes Roberto , Afonso Pedro , Álvaro Nuno V. , Milla-Figueras David , Neto Raul M. A. , Tittley Ian , Moreu Ignacio
Published: October 2020

The macroalgal flora of Graciosa (central group of Azores archipelago) is poorly known, with only 116 species recorded so far (authors personal data). The published information reflects occasional collections from sporadic field visits to the Island. To overcome this, a thorough investigation under the Expedition “GRACIOSA/2004”, the Campaigns “PADEL/2006”, “MACROBIOLMOL/2014” and “PIMA-BALA/2017” involving sample collecting and presence data recording, was undertaken over an area of 19 km2 encompassing littoral and sublittoral levels down to about 40 m around the Island. This paper lists the taxonomic records and provides information on species ecology and occurrence around the Island improving the knowledge of the Azorean macroalgal flora at both local and regional scales.

A total of 1692 specimens belonging to 250 taxa of macroalgae (and including 55 taxa identified only at the genus level) are registered, comprising 166 Rhodophyta, 36 Chlorophyta and 48 Ochrophyta (Phaeophyceae). From these, 195 are identified to the species level (126 Rhodophyta, 31 Chlorophyta and 38 Ochrophyta) and comprise 156 native, 20 of uncertain origin and 14 introductions to the Island. Predaea feldmannii subsp. azorica Gabriel is an Azorean endemic, whereas Codium elisabethiae O.C. Schmidt, Botryocladia macaronesica Afonso-Carrillo, Sobrino, Tittley & Neto, Phyllophora gelidioides P.Crouan & H.Crouan ex Karsakoff and Laurencia viridis Gil-Rodríguez & Haroun represent Macaronesian endemics. Seventy-nine species are newly recorded to the algal flora of the Island.
Marine algal (seaweed) flora of Terceira Island, Azores
Authors: Neto Ana I. , Prestes Afonso C. L. , Álvaro Nuno , Resendes Roberto , Neto Raul M. A. , Moreu Ignacio
Published: October 2020

As for many other Azorean Islands, the macroalgal flora of Terceira (belonging to the central group of the archipelago) is poorly known, the published information reflecting occasional collections of sporadic visitors to the island. In order to overcome this and contribute to improve the knowledge of Azorean macroalgal flora at both local and regional scales, a thorough investigation was conducted. Both collections and presence data recordings were undertaken at the littoral and sublittoral levels down to approximately 40 m around the island, covering a total area of approximately 49 km2. This paper lists the taxonomic records and provides information on each species’ ecology and occurrence on the Island’s littoral.

A total of 418 specimens (including taxa identified only to genus level) belonging to 147 taxa of macroalgae, comprising 95 Rhodophyta, 33 Chlorophyta and 19 Ochrophyta (Phaeophyceae) are registered. Of these, 113 were identified to species level (73 Rhodophyta, 24 Chlorophyta and 16 Ochrophyta), encompassing 35 new records for the Island (27 Rhodophyta, 6 Chlorophyta and 2 Ochrophyta). Most species are native, including the Macaronesian endemisms Codium elisabethiae O.C.Schmidt, Millerella tinerfensis (Seoane-Camba) S.M.Boo & J.M.Rico and Phyllophora gelidioides P.Crouan & H.Crouan ex Karsakoff. Eight species are introduced and 15 have uncertain origin.
Immunomodulatory effect of melatonin supplementation in experimental diabetes
Authors: Ivankiv Yana I. , Oleshchuk Oleksandra M.
Published: October 2020

Aim: To investigate the effect of melatonin on the immunomodulatory response in experimental type 1 and 2 diabetes mellitus.

Methods: Experiments were performed on male rats (180–200 g), purchased from the Experimental Animal Holding,. Animals were maintained in standard diet conditions. Two pathological states were simulated on male rats: experimental type 1 and type 2 diabetes. Melatonin was introduced from 14 to 23 days of experiment intraperitoneally. Levels of immunoglobulin classes A, M and G (Ig A, M, G), circulating immune complexes (CIC), interleukin 1β (EE), interleukin 6 (IL-6), and tumor necrosis factor (TNF-a) were measured.

Results: We demonstrated that melatonin in case of immune hyperactivity, can, provide a suppressive effect and is able to enhance immune reactivity under conditions of its limitation, indicating the immunostimulating activity. Furthermore, we found that administration of melatonin decreased inflammatory responses by mediating the levels of immunomodulatory factors, including TNF-α, IL-1β and IL-6.

Conclusion: Melatonin is a positive regulator of immune system, may be a potential therapeutic agent, it has no reported side effects.
Prison Sentencing and Criminal Activity: A Dynamic Model
Authors: Pelletan Jacques
Published: October 2020

Un modèle dynamique d’allocation temporelle entre activités légales et illégales est proposé dans cet article, en considérant ces activités comme substituables. L’impact à long terme de l’emprisonnement sur l’activité criminelle est plus particulièrement analysé. Deux prolongements sont discutés : une inflation des sanctions pour les récidivistes et un recours à des sanctions « éducatives ». JEL: J22, K14, K42
L’intégration de l’économie belge dans les chaînes de valeur mondiales : le rôle des exportateurs et de leurs fournisseurs domestiques
Authors: Hambÿe Caroline , Michel Bernhard
Published: October 2020

La réorganisation des processus de production au cours des dernières décennies en chaînes de valeur de plus en plus fragmentées au-delà des frontières pose de nouveaux défis pour l’analyse de l’intégration de la Belgique dans l’économie mondiale. Dans cet article, nous examinons la participation et la position de la Belgique dans les chaînes de valeur mondiales sur base de données macro-sectorielles issues d’un tableau entrées-sorties auxquelles nous avons associé des données individuelles par entreprise pour mieux cerner les rôles joués par les entreprises manufacturières hautement exportatrices et celles peu ou pas exportatrices. La prise en compte de cette hétérogénéité permet de montrer (i) qu’au sein des branches manufacturières, le processus de production des entreprises hautement exportatrices diffère de celui des autres entreprises, (ii) que ces entreprises manufacturières hautement exportatrices sont plus intégrées dans les chaînes de valeur mondiales et (iii) que leurs exportations génèrent une valeur ajoutée domestique considérable et de nombreux emplois en Belgique, dont une part substantielle dans des entreprises non manufacturières. Codes JEL : C67, F14, F15, F16
Participation aux échanges internationaux et caractéristiques des entreprises
Authors: Dhyne Emmanuel , Duprez Cédric
Published: October 2020

Au cours des dernières décennies, les processus de production se sont fragmentés tant au niveau international qu’au niveau domestique. Si la dimension internationale de ce phénomène a été largement documentée dans la littérature, la dimension domestique, au-delà des relations intersectorielles documentées dans les matrices Input-Output est moins souvent analysée du fait de la faible disponibilité de données microéconomiques documentant les relations entre entreprises. L’objet de cet article est de documenter ces relations B2B au niveau microéconomique en Belgique et d’identifier l’intégration directe et indirecte des entreprises belges aux chaînes globales de valeur. Nos analyses montrent que cette fragmentation et la plus ou moins grande participation aux échanges internationaux génèrent des gains de productivité. Codes JEL : D22, F61, L23
Position des entreprises dans la chaîne de valeur, productivité, salaires et profits : qu’en dit la littérature ?
Authors: Mahy Benoît , Rycx François , Vermeylen Guillaume , Volral Mélanie
Published: October 2020

Les processus de production sont devenus de plus en plus fragmentés durant ces trois dernières décennies, menant à l’émergence de ce qu’il est convenu d’appeler des chaînes de valeur mondiales (CVM). Cette fragmentation concerne particulièrement les petites économies ouvertes comme la Belgique. Dhyne et Duprez (2015) ont ainsi montré que 82 % des entreprises commerciales belges ont produit, entre 2002 et 2012, des biens et services qui étaient directement ou indirectement exportés. Dans ce contexte, cet article propose d’aborder la littérature qui concerne les effets de la participation des firmes dans les CVM, surtout sous l’angle de la position qu’elles occupent dans ces chaînes. Ces effets sont analysés en termes de productivité et de partage de la rente entre salaires et profits. Nous nous focalisons sur les études menées au niveau de la firme, et accordons une importance particulière aux résultats empiriques en lien avec l’économie belge. Classification JEL : F61, J24, D30, D40, J50
Upstreamness, wages, and workers’ origin: A review of the literature
Authors: Fays Valentine , Mahy Benoît , Rycx François
Published: October 2020

Durant ces dernières décennies, les processus mondiaux de production de biens et de services sont devenus de plus en plus fragmentés. Cette fragmentation, particulièrement prononcée au sein des petites économies ouvertes telle que la Belgique, a entraîné l’émergence de chaînes de valeur mondiales (CVM). Parallèlement, l’immigration nette dans les pays de l’OCDE est demeurée positive, et ce depuis les années 1960. Par ailleurs, entre 2000 et 2017, le nombre de résidents nés à l’étranger (c’est-à-dire les migrants de première génération) a augmenté de plus de 50% au sein des pays de l’OCDE (OCDE, 2018). Sur base de ces constats, cet article vise à fournir un aperçu de la littérature concernant le lien entre la position (plus ou moins en amont) des firmes dans les chaînes de valeur et l’écart de salaires entre travailleurs natifs et migrants. A cette fin, nous abordons tout d’abord les sources potentielles d’inégalités de salaires basées sur l’origine des travailleurs. Ensuite, nous présentons les principaux résultats relatifs à l’impact de la position de la firme dans les CVM sur le salaire des travailleurs en général, puis plus particulièrement sur les inégalités de salaires entre travailleurs natifs et migrants. Ce faisant, nous consacrons une attention particulière aux résultats empiriques concernant l’économie belge. Classification JEL : J15, J31, F16
Trade, GVCs, and wage inequality: Theoretical and empirical insights
Authors: Gagliardi Nicola , Mahy Benoît , Rycx François
Published: October 2020

Une question importante dans les débats actuels concerne la concomitance entre la croissance des inégalités de revenus au sein des économies avancées et l’exposition croissante de ces économies au commerce international. Cet article contribue à ces débats en fournissant une synthèse de la littérature théorique et empirique traitant de l’influence de la mondialisation sur un aspect particulier des disparités de revenus, à savoir les inégalités salariales. Une attention particulière est accordée au rôle du commerce, en particulier aux exportations et aux importations, ainsi qu’aux chaînes de valeur mondiales. L’analyse souligne la nécessité d’examiner en profondeur plusieurs mécanismes interdépendants pour répondre avec précision aux préoccupations en matière d’inégalités induites par le commerce. Classification JEL: F11, F12, F14, F16, F66, J31
Merci à nos relecteurs, réviseurs et correcteurs ! ou Comment fonctionnons-nous
Authors: Naszályi Philippe
Published: October 2020

Notre revue contre vents et marées depuis 1965, • pense que la recherche en gestion n’est pas le monopole des anglo-américains, • refuse les contributions, qu’acceptent pourtant des revues encore francophones et souvent mieux « rankées « que nous, qui ne sont que de mauvais « remakes » souvent mal traduits d’ailleurs de pensées américanisées, • favorise les jeunes auteurs et les auteurs aux cultures et pratiques différentes du « main stream », et de ce fait a permis de faire émerger nombre de respectables « professeurs » • a tenu, durant cette crise à ne pas modifier sa rigueur unique et son fonctionnement international Toutes les propositions qui nous sont adressées, sont analysées par TROIS évaluateurs dont au moins, n’est pas hexagonal Après les différents échanges entre auteur(s) et évaluateurs, le texte définitif est ensuite adressé à DEUX RELECTRICES pour • la langue, • l’orthographe, • la vérification de toutes les sources et références bibliographiques contenues par chaque article. Je mets au défi les évaluateurs, rankeurs , et autres « classeurs » de revues de trouver une telle rigueur ailleurs !
L’impact des caractéristiques du comité d’audit sur la détresse financière
Authors: Jarrar Hajer , Lefebvre Quentin , Salloum Charbel , Gebrayel Elias
Published: October 2020

L’objet de cette recherche est de déterminer l’impact des caractéristiques des comités d’audit sur les banques libanaises saines et en détresse financière. Quatre caractéristiques des comités d’audit seront analysées : la taille, la composition, la fréquence des réunions et l’expertise financière des membres. L’échantillon comprend 54 banques libanaises. La variable de rentabilité a permis de déterminer si une banque est en situation de détresse financière ou pas. Nos résultats montrent que la détresse financière des banques est liée de manière négative et significative à la fréquence des réunions du comité d’audit et à la taille de la banque.
Comment associer la DSI et les Métiers pour exploiter au mieux les données que génère toute activité humaine ?
Authors: Chauvin Stéphanie , Igonetti Jean-Baptiste
Published: October 2020

Les techniques de détection de connaissances permettent d’améliorer la compréhension de phénomènes croisés. À destination des utilisateurs profanes des statistiques et de la data science, cet article présente une mécanique pour accélérer la détection de diagnostics pertinents pour les métiers, pour la prise de décision et permet d’interroger certains concepts des sciences de gestion en rapport avec la résistance aux changements ou la montée en compétence des utilisateurs.
L’impact de la digitalisation sur l’écosystème d’affaires de la Supply chain
Authors: Couzineau-Zegwaard Elizabeth
Published: October 2020

Cet article a pour vocation de comprendre l’impact de la digitalisation sur la supply chain à partir de l’exemple de Control Towers. Pour décrypter les conséquences de ces évolutions, nous avons mobilisé les concepts d’écosystèmes d’affaires et de firmes pivots et mis en œuvre la méthode DELPHI auprès d’un panel de 13 experts. Les premiers résultats montrent une évolution importante des jeux ‘acteurs au sein de l’écosystème avec en particulier le transfert de rôle de firme pivot vers les entreprise SSII capables de mettre à disposition des acteurs les Control Towers, plateformes centrales de la gestion, de la traduction et de la mise à disposition des données à l’ensemble de l’écosystème, promettant ainsi la visibilité de l’ensemble de la supply chain.
Vie privée et intimité
Authors: Levy Yann , Tarnaud Laurent
Published: October 2020

La digitalisation, et le Web 2.0 en particulier, ont considérablement développé les possibilités d’interactions entre les individus, aussi bien dans le cadre d’échanges interpersonnels qu’entre les marques et leurs publics. Avec ces possibilités, les problématiques liées à la protection de la vie privée n’ont cessé de s’amplifier pour devenir une préoccupation centrale, tant dans la recherche en marketing, qu’à l’échelle managériale, et au regard du droit. Si ces trois univers ont développé des cadres définitionnels du concept de vie privée, et des mesures de sa protection qui leur sont propres, des différences considérables subsistent et complexifient les chances d’en avoir une vision consensuelle et en adéquation avec la représentation que s’en font les individus. Ainsi, la vie privée définie par le droit ne semble pas intégrer le caractère digital spécifique au web 2.0. Elle n’est, de plus, pas systématiquement la même que celle observée par les professionnels, qui définissent le respect de la vie privée de leur client par l’obtention de leur consentement. À nouveau, ces visions diffèrent de celle décrite par les utilisateurs qui associent et confondent la vie privée avec un autre concept, celui d’intimité, paradoxalement très minoritaire dans les textes de loi. Au moyen d’une méthodologie différente de celles habituellement utilisées dans la recherche sur la vie privée, nous proposons une nouvelle approche, basée sur la théorie des représentations sociales, par laquelle nous interrogeons les individus sur leur définition de la vie privée, de l’intimité et de la version digitale de ces deux concepts afin d’en déterminer les similitudes, les distinctions et les liens entre les visions des chercheurs, des managers, du droit et enfin des utilisateurs.
Évolution du style motivationnel des enseignants au cours de leur première année d’enseignement
Authors: André Amaël
Published: October 2020

Basée sur la théorie de l’autodétermination, cette recherche vise à la fois à étudier l’évolution du style motivationnel des enseignants débutants au cours de leur année de stage et à identifier les éventuels obstacles à son évolution. Une méthodologie mixte a été utilisée. Le style perçu de 126 enseignants stagiaires a d’abord été mesuré par questionnaire en début, milieu et fin d’année. Ensuite, des entretiens semi-directifs ont été conduits avec 12 d’entre eux afin de mieux comprendre les évolutions quantitatives. Les résultats indiquent que les trois dimensions du style perçu évoluent différemment au cours de l’année. Si les niveaux de structure et d’implication interpersonnelle augmentent, le soutien de l’autonomie reste stable. Malgré des croyances initiales plutôt favorables au soutien de l’autonomie, face à la réalité des classes, les enseignants perçoivent souvent ce dernier comme peu adapté pour favoriser l’engagement de leurs élèves.
The Role of Fire in the Posthumous Customs of Podlachia on the Border of Poland and Belarus
Authors: Wawrzeniuk Joanna
Published: October 2020

In this article, I would like to describe the role of fire in the customs of All Souls’ Day in the Easter period called przewody or radunica. The burning of the fires most commonly took place overnight at home and in cemeteries to illuminate the way for the transmigration of souls so they would not harm the living. The reflection of special respect for fire is known from the funeral rites from the area of Podlachia in the Middle Ages. It also served as a basic element of the ritual related to cyclical visits to the dead, as evidenced by the remains of charcoals or ash. Different kind of sources from the Middle Ages and modern times, from the region of eastern Poland (Podlachia and Belarus, in particular) shall be used to confirm that the rite lasted for many years.
Aproximación a Yehudá Amijai
Authors: Bejarano Escanilla Ana Maria
Published: October 2020

La Literatura hebrea en Israel experimentó una fuerte conmoción en los años cincuenta con la aparición de las primeras voces individualistas en la prosa y en la poesía, después de haber estado dominada por la izquierda socialista durante los años treinta y cuarenta. Una de esas voces individualistas fue la de Yehudá Amijai que ha llegado a ser una de las principales figuras de la poesía hebrea moderna. El artículo que aquí se presenta es una visión de conjunto de la personalidad y de la obra poética de Amijai, así como de la realidad social y literaria en la que surgió y continuó escribiendo después.
Los poemas de Šelomoh ibn Gabirol en el ritual de Pesaḥ según las haggaḏôṯ John Rylands y Sarajevo
Authors: Cano Maria José
Published: October 2020

Se recogen y cotejan los nueve poemas de Ibn Gabirol que aparecen en dos haggaḏôṯ de Pesaḥ de origen sefardí, la de Sarajevo y la de John Rylands. Las variantes encontradas no son relevantes, fundamentalmente consisten en el empleo de escritura plena.
Movimiento mesiánico hispano-portugués: Badajoz 1525
Authors: Carrete Parrondo Carlos , Moreno Koch Yolanda
Published: October 2020

Se presenta una carta fechada en Badajoz el 30 de marzo de 1528, firmada por el inquisidor de dicha ciudad y dirigida al rey de Portugal, en la que se expone una anómala situación socio-religiosa sobre un tardío movimiento mesiánico.
Cantar de los Cantares Rabbâ 4, 7-8. Edición crítica
Authors: Girón Luis F.
Published: October 2020

Se presenta la edición crítica de Cantar de los Cantares Rabba 4,7-8, sobre la base del texto del Ms. Kaufmann n2 27 de Budapest, procedente de la gĕnizâ, con aparato de variantes de otros seis textos entre manuscritos y ediciones.
Versión manuscrita de la copla sefardf La castidad de José
Authors: Hassán Iacob M.
Published: October 2020

Presentación y remisiones bibliográficas de las varias coplas sefardíes de tema josefino, inventario de textos sefardíes del ms. Heb. 8º 3191 de la JNUL de Jerusalén, edición en caracteres latinos y estudio de la versión aljamiada de la copla La castidad de José incluida en dicho manuscrito (fols. 9b-1Ob ), noticia de otras dos versiones inéditas de dicha copla, todo ello a propósito de la mención, en un articulo de hace años de F. Diaz Esteban, de la primera versión publicada de la copla en cuestión.
Una curiosa inscripción hebrea del siglo XIX en el Castillo de Guadamur (Toledo)
Authors: López Álvarez Ana María , Palomero Plaza Santiago
Published: October 2020

En el castillo de Guadamur situado a 14 km. de Toledo, construido en el reinado de Enrique IV de Castilla por don Pedro López de Ayala el «el mozo», existe una inscripción hebrea bajo el artesonado de la habitación conocida como «árabe», con los versículos 2-4 y la primera palabra del 5. del Salmo 30, realizada durante la restauración del citado castillo en el siglo XIX. Posiblemente el conde de Cedillo que colaboró en la restauración con el dueño del castillo en esa época, don Carlos Morenes y Tord, Barón de las Cuatro Torres y Conde del Asalto, se inspiró en una inscripción similar existente en la galería de mujeres de la Sinagoga del Tránsito y hoy perdida en gran parte.
Jewish Altitudes to Christian Power in Medieval Spain
Authors: Assis Yom Tov
Published: October 2020

La actitud de los judíos frente al poder cristiano en la España medieval está profundamente influenciada por dos factores: la tradicional actitud judía hacia los gobiernos no judíos en el exilio y las condiciones cambiantes de la posición de los judíos en cualquier tierra o periodo dados. El importante papel desempeñado por los judíos en los dos grandes reinos de Castilla y Aragón los acercó más que nunca a las cortes cristianas. Las fuentes legales hebreas reflejan el respeto y amistad que sentían los líderes judíos hacia la realeza y los reyes en la peninsula ibérica.
«Duelos os dé Dios ... e avrá christiandad». Nueva página sobre el criptojudaísmo castellano
Authors: Carrete Parrondo Carlos , Moreno Koch Yolanda
Published: October 2020

Este artículo presenta un análisis del proceso inquisitorial incoado contra el judaizante Ginés de Moya, vecino de Cuenca, en el año 1490. Se incluye además un cuadro genealógico y el comentario de un médico judío, vecino de Huete (Cuenca), que consideramos de especial interés para una mejor comprensión del criptojudaismo castellano.
Tamsulosin plus a new complementary and alternative medicine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: Results from a retrospective comparative study
Authors: Fusco Ferdinando , Creta Massimiliano , Trama Francesco , Esposito Fabio , Crocetto Felice , Aveta Achille , Mangiapia Francesco , Imbimbo Ciro , Capece Marco , La Rocca Roberto , Mirone Vincenzo , Longo Nicola
Published: October 2020

Background: We aimed to compare the efficacy of tamsulosin 0.4 mg once a day alone and the combination therapy involving tamsulosin 0.4 mg once a day plus the complementary and alternative medicine consisting of vitamins (C and D), herbal products (Cucurbita maxima, Capsicum annum, Polygonum capsicatum) and amino acid L-Glutamine bid in patients with lower urinary tract symptoms related to benign prostatic hyperplasia (LUTS/BPH). Methods: We performed a retrospective matched paired comparison. The clinical records of LUTS/BPH patients who underwent medical therapy with tamsulosin 0.4 mg/day plus the complementary and alternative medicine consisting of vitamins (C and D), herbal products (Cucurbita maxima, Capsicum annum, Polygonum capsicatum) and amino acid L-Glutamine bid between January 2019 to September 2019 were reviewed (Group 1). These patients were compared in a 1:1 fashion with LUTS/BPH patients who underwent therapy with tamsulosin 0.4 mg/day alone (Group 2). Total, storage, voiding and Quality of Life (QoL) international prostate symptom (IPSS) score, as well as overactive bladder (OAB)-v8 score and treatment- related adverse events recorded at 40 days follow-up in both groups were compared.Results: At 40 days follow-up mean total, storage, voiding and QoL IPSS sub-scores as well as OAB-v8 score significantly improved in both groups. Intergroup comparison showed statistically significant lower mean total IPSS score (11.6 vs 12.4, p = 0.04) mean storage IPSS sub-score (6.5 vs 7.5, p = 0.01), and mean OAB v8 score (16.7 vs 18.8, p = 0.03) in patients in the Group 1. Conclusions: The combination of tamsulosin 0.4 mg/die plus the complementary and alternative medicine consisting of vitamins (C and D), herbal products (Cucurbita maxima, Capsicum annum, Polygonum capsicatum) and amino acid LGlutamine bid provides statistically significant advantages in terms of storage LUTS improvements in patients with LUTS/BPH compared to tamsulosin 0.4 mg/day alone. These findings are preliminary and further prospective studies on a greater number of patients are needed to confirm it.
Bone pain palliation outcomes and possibility of Radium-223 re-treatment in mCRPC
Authors: Frantellizzi Viviana , Lazri Julia , Pontico Mariano , Pani Arianna , De Vincentis Giuseppe
Published: October 2020

Objective. Bone secondary localizations from metastatic castration-resistant prostate cancer are associated with an increase in mortality and a reduction in the patient’s quality of life. Radium-223 is a targeted alpha-therapy approved for the treatment of mCRPC (metastatic castration resistant prostate cancer) patients with symptomatic bone metastases. To our knowledge, no previous study has been performed assessing the bone pain palliation outcomes following Radium-223 therapy. Materials and Methods. A mCRPC patient with symptomatic bone localizations and relevant bone pain symptoms has been subjected to Radium-223 treatment. Pain was assessed over time from the first administration of Radium-223 to follow-up. Results. After Radium-223 treatment, patient showed a significant BPI (Brief Pain Inventory) decline from 7 to 4 and a concomitant partial regression of multiple bone hot spots in the bone scan exam. Three months after the last infusion of Radium-223, further BPI decline (from 4 to 2) with bone scan depicting stable disease was observed. However, after 6 months from Radium-223 treatment end, BPI increased from 2 to 10. Conclusions. Taking into account the effectiveness on bone pain relief and the low toxicity profile showed by Radium-223 treatment, we encourage further analysis on large cohort to investigate the clinical outcome after Radium-223 treatment, in terms of bone pain palliation, together with the possibility of Radium-223 re-treatment in selected patients..
Transperitoneal and retroperitoneal approach in laparoscopic partial nephrectomy for posterior cT1 renal tumors: A retrospective, two-centers, comparative study
Authors: Ferakis Nikolaos , Katsimantas Antonios , Charalampogiannis Nikolaos , Paparidis Spyridon , Rassweiler Jens Jochen , Gozen Ali Serdar
Published: October 2020

Objectives: To compare perioperative, oncological and functional outcomes of Laparoscopic Transperitoneal Partial Nephrectomy (LTPN) and Retroperitoneal Laparoscopic Partial Nephrectomy (LRPN) for posterior, cT1 renal masses (RMs). Materials and methods: Databases of two urologic institutions applying different laparoscopic surgical approaches on posterior cT1 RMs between June 2016 and November 2018 were retrospectively evaluated. Data on patient demographics, perioperative data and tumor histology were collected and further analyzed statistically. Results: Each group consisted of 15 patients. Baseline characteristics were comparable in each group. When compared to LTPN, LRPN was associated with significantly shorter operative time (OT) (115 min versus 199 min, p < 0.05). No significant differences were detected in the other outcomes. Conclusions: LRPN is associated with a significantly shorter OT compared to LTPN for posterior cT1 RMs. Both surgical approaches are safe, feasible and credible, demonstrating optimal results.
The impact of tumor invasion to muscularis mucosaevascular plexus on patient outcome in pT1 bladder urothelial carcinoma
Authors: Sahan Ahmet , Gerin Fatma , Garayev Asgar , Bozkurtlar Emine , Çubuk Alkan , Ozkaptan Orkunt , Ertas Kasım , Tanıdır Yıloren , Cam Haydar Kamil , Tınay Ilker
Published: October 2020

Objectives: T1 bladder cancer has a wide range of tumor behavior and lamina propria invasion depth has a high potential risk of disease progression. To evaluate the patient outcome according to the tumor invasion to the muscularis mucosae-vascular plexus (MM-VP) in pT1 bladder urothelial carcinoma (BUC). Materials and methods: This study is a retrospective analysis of patients consecutively recorded from 2007 to 2013. A total of 93 patients with a history of primary pT1 BUC and complete follow-up were included. We used a pathological substaging system according to the tumor invasion regarding the MM-VP: pT1a (invasion above MM-VP) and pT1b (MM-VP invasion). We evaluated recurrence-free survival (RFS), progression- free survival (PFS), disease-specific-survival (DSS) based on this sub-staging system. Results: Pathological evaluation regarding the MM-VP invasion revealed 53 patients (57%) as pT1a BUC and 40 patients (43%) as pT1b BUC. The mean follow-up was 78.8 months. During the follow-up period; 60 patients (64.5%) had tumor recurrences, 32 patients (34.4%) had progression to invasive disease, 18 patients (19.4 %) died during follow-up related to the BUC. In 29 (54.7%) of pT1a and in 31(77.5%) of pT1b tumors, the recurrent disease was recorded during the followup period (p = 0.023). DSS rates at 5 years for pT1a and pT1b were 80.2% and 60.8%, respectively. PFS, RFS, and DSS rates were similar for pT1a/pT1b and did not reach statistical significance (p > 0.05). Conclusions: Sub-staging of pT1 BUC according to the MM-VP invasion showed a limited impact on the outcome in our patient cohort. However, the presence of pT1b disease caused a significantly higher rate of recurrence.
Respiratory symptoms and associated risk factors among under-five children in Northwest Ethiopia: community based cross-sectional study
Authors: Andualem Zewudu , Taddese Asefa Adimasu , Azene Zelalem Nigussie , Azanaw Jember , Dagne Henok
Published: October 2020

Introduction: Acute respiratory infections are still a major public health problem resulting in morbidity and mortality among under-five children. This study aims to assess the extent of respiratory symptoms and associated risk factors among under-five children in Gondar city, Northwest Ethiopia. Methods: A community-based cross-sectional study was carried out from February to June 2019. From 792 study participants, data were collected via face to face interviews by using a semi-structured pre-tested questionnaire. Data were entered in Epi Info version 7 then exported to Stata 14.00 for analysis. Binary (Bivariable and Multivariable) logistic regression analysis was used to test the association of explanatory and outcome variables. Variables with p<0.05 were considered as significantly associated with the outcome variable.Results: The prevalence of respiratory symptoms among under-five children was 37.5% at [95% (CI: 34.3-41)]. Uterine irritability during pregnancy [AOR = 1.89 at 95% CI: (1.11-3.23)], physical exercise during pregnancy [AOR = 0.60 at 95% CI: (0.41-0.89)], using wood and coal for heating [AOR = 2.42 at 95% CI: (1.65-3.53)], cockroaches infestation [AOR = 1.95 at 95% CI: (1.36 – 2.90)], presence of new carpets [AOR = 2.38 at 95% CI: (1.33-4.29)], damp stain [AOR = 2.45 at 95% CI: (1.02-2.69)], opening windows during cooking [AOR = 0.58 at 95% CI: (0.36 - 0 .93)], living less than 100 m heavy traffic [AOR = 1.94 at 95% CI: (1.16-3.27)], and living less than 100 m (unpaved roads/streets) [AOR= 2.89 at 95% CI: (1.89-4.55)] were significantly associated with respiratory symptoms.Conclusion: The prevalence of respiratory symptoms among under-five children was relatively high in the study area. Personal and environmental characteristics influencing symptom occurrence were identified. Respiratory symptoms will be minimized by reducing exposure to indoor and outdoor air pollution and enhancing housing quality.
A novel homozygous frameshift mutation in MNS1 associated with severe oligoasthenoteratozoospermia in humans
Authors: Li Yong , Wang Wei-Li , Tu Chao-Feng , Meng Lan-Lan , Hu Tong-Yao , Du Juan , Lin Ge , Nie Hong-Chuan , Tan Yue-Qiu
Published: October 2020

Oligoasthenoteratozoospermia (OAT) refers to the combination of various sperm abnormalities, including a decreased sperm count, reduced motility, and abnormal sperm morphology. Only a few genetic causes have been shown to be associated with OAT. Herein, we identified a novel homozygous frameshift mutation in meiosis-specific nuclear structural 1 (MNS1; NM_018365: c.603_604insG: p.Lys202Glufs*6) by whole-exome sequencing in an OAT proband from a consanguineous Chinese family. Subsequent variant screening identified four additional heterozygous MNS1 variants in 6/219 infertile individuals with oligoasthenospermia, but no MNS1 variants were observed among 223 fertile controls. Immunostaining analysis showed MNS1 to be normally located in the whole-sperm flagella, but was absent in the proband's sperm. Expression analysis by Western blot also confirmed that MNS1 was absent in the proband's sperm. Abnormal flagellum morphology and ultrastructural disturbances in outer doublet microtubules were observed in the proband's sperm. A total of three intracytoplasmic sperm injection cycles were carried out for the proband's wife, but they all failed to lead to a successful pregnancy. Overall, this is the first study to report a loss-of-function mutation in MNS1 causing OAT in a Han Chinese patient.
Management of Hand Spasticity with Ultrasound-guided Ethyl Alcohol Injection to the Deep Branch of the Ulnar Nerve
Authors: Chang Min Cheol , Boudier-Revéret Mathieu
Published: October 2020

Patients with stroke commonly experience limb spasticity, which can prevent functional recovery and cause functional disability, due to muscle tightness and joint stiffness in the affected limb. Using the ability of ultrasound (US) to visualize nerves, we successfully performed US-guided neurolysis of the motor branch of the ulnar nerve in Guyon's canal, while avoiding injury of its sensory branch, in a 63-year-old woman with upper limb poststroke spasticity. We believe that our method has the merit of precluding the development of neuropathic pain, following injury to the sensory branch of the ulnar nerve. Moreover, our method reduces operation time and perioperative pain.
In vitro Demonstration of Melanoma Metastasis in Lymph Nodes of Prepared Specimens Using a Light-emitting Diode-based Multispectral Photoacoustic Ultrasound Imaging System
Authors: Ohta Tomoyuki , Shirakawa Takako , Okada Shinya , Ishii Naohiro , Kiryu Shigeru
Published: October 2020

Although an excellent photoacoustic (PA) ultrasound method has been reported for the evaluation of lymph node melanoma metastasis in animal experiments, it remains to be evaluated in clinical trials. Recently, we performed PA ultrasound assessment using light-emitting diodes to detect metastatic melanoma in the lymph nodes of specimens prepared for microscopic examination. The PA effect was not obvious in amelanotic melanoma, but was seen in melanotic melanoma by PA imaging (PAI) and histopathological correlation in cases of primary melanotic melanoma accompanied by metastatic lymph nodes, including the coexistence of amelanotic melanoma and melanotic melanoma. Clinical workup should be performed with not only PAI but also conventional ultrasonography in cases with metastasis related to amelanotic transformation, which would likely be missed by PAI alone.
Impacted Fish Bone in Buccal Space Associated with an Abscess
Authors: Rayudu Naren Kishore , Palla Santosh , Vaaka Phani Himaja Devi , Rao Dagilla Priyanka
Published: October 2020

Fish bone impaction in buccal space abscess is an uncommon dental scenario. A case of young adult with partially edentulous state contributing to this emergency is presented. The history, clinical imaging findings, surgical procedure, and checklist for clinical assessment are briefly described. The point-of-care ultrasonography (POCUS) was used in our case to identify, locate, and perform an ultrasonography-guided removal of impacted fish bone in consolidated abscess of the buccal space. The role of POCUS in cases of dental swellings or uncommon emergencies is emphasized in clinical settings.
Abdominal Ultrasound in the Detection of an Incidental Paraganglioma
Authors: Chen Hsiao-Ting , Cheng Yung-Yin , Tsao Teng-Fu , Peng Cheng-Ming , Hsu Jeng-Dong , Tyan Yeu-Sheng
Published: October 2020

Paraganglioma is a tumor that originates from neuroendocrine cells of the sympathetic or parasympathetic systems. Patients may suffer from headaches, palpitations, diaphoresis, and hypertension due to catecholamine excess or symptoms from the mass effect of the tumor. In the absence of typical symptoms of catecholamine excess, the diagnosis of a nonfunctional paraganglioma is often delayed. Herein, we report a case of a 63-year-old female patient with a nonfunctional paraganglioma which is an accidental finding during investigation of a fever. Abdominal ultrasonography incidentally detected this lesion as a complex, solid, cystic mass in the left suprarenal retroperitoneum.
Preoperative Diagnosis of a Torsioned Accessory Spleen
Authors: Yoshida Miki , Saida Tsukasa , Masuoka Souta , Urushibara Aiko , Chiba Fumiko , Masumoto Kouji
Published: October 2020

We report a case of a 12-year-old boy with an accessory spleen torsion. He presented with left-sided abdominal pain after trauma. A 4 cm oval mass without contrast enhancement was detected on contrast-enhanced computed tomography (CT), and ultrasound (US) showed a 4 cm oval mass below the spleen. The mass mainly consisted of high echoes similar to the spleen; the central part showed irregularly low echoes. Subsequent follow-up daily US examinations showed gradual expansion of the central low echoes with conspicuous hyperechoic dots. Discontinuation of the branch from the splenic artery to the mass was observed, both, on US and CT. These findings led to the diagnosis of a hemorrhagic infarct caused by torsion of the accessory spleen. Laparoscopy showed adherence of the accessory spleen to the omentum and colon by twisting four times around its axis. It was resected and confirmed the diagnosis of a torsioned accessory spleen.
Sonographic Assessment of Some Abdominal Organs in Children with Sickle Cell Disease in Ilorin, Nigeria
Authors: Muftaudeen Basirat , Eze Joseph C. , Sidi Muhammad , Miftaudeen Mutiat Nike
Published: October 2020

Background:

The irregular sickle cells can block blood vessels, causing tissue and organ damage and in most cases presented with pain as a result of organ ischemia. Ultrasonography is an easily available instrument for investigating abdominal organs which are most commonly affected by sickle cell disease (SCD). This study was aimed to assessing liver, gall bladder, spleen, and kidney in children with SCD in Ilorin, Kwara State.

Methods:

A prospective cross-sectional study was conducted among children with SCD in Ilorin from September 2017 to April 2018. An ethical approval was obtained from the Human Research and Ethics Committee of the Kwara State Ministry of Health. In this study, 106 children with SCD and 106 normal children for control were included. Abdominal ultrasound scan was performed on all the selected subjects and the findings were recorded on the data capture sheet. Descriptive and inferential statistic was used in the data analysis, SPSS version 20 was used and the P = 0.05.

Results:

In the children with SCD, hepatomegaly was found in 45 (42.5%), 29 (27.4%) had coarse echo pattern of liver and 16 (15.1%) had hyperechoic liver, 5 (4.7%) had gallbladder stone, 2 (1.9%) had gallbladder sludge, and 6 (5.6%) had thickened gallbladder wall. Twenty-five (23.6%) had splenomegaly, and 7 (6.6%) had autosplenectomy. Four (3.8%) showed reduced corticomedullary differentiation in each kidney, five (4.7%) in each kidney had mild calyceal dilatation. One (0.9%) had mild calyceal dilatation with reduced corticomedullary differentiation with accompanying loss of renal sinus fat.

Conclusion:

Abdominal ultrasound imaging for patients with SCD showed a high incidence of abdominal abnormalities, especially in solid organs such as liver, kidney, and spleen.
Renal Volumetry-based Prediction of the Presence of Accessory Renal Artery
Authors: Qaseem Syed Mohammad Danish , Singhal Anoop , Ghonge Nitin P.
Published: October 2020

Background:

The objective was to validate the hypothesis and evaluate whether the presence or absence of accessory renal artery can be predicted on the basis of volumetric parameters of kidney and diameter of the main renal artery (mRA).

Methods:

This retrospective analysis was performed in a total of 60 kidneys in 30 patients, who had computed tomographic (CT) angiography. The kidneys were segregated into control and study groups depending on the absence or presence of accessory renal artery. The total renal volumes were measured using renal length, breadth, and height in mm3. The renal artery diameters were also measured in mm, in the postostial segment. Renal volume/renal artery diameter (V/d) was measured for each kidney in two groups, and the difference in mean V/d values (in mm2) in two groups was measured for statistical significance.

Results:

The mean V/d value in the study group with presence of the accessory renal artery was found to be 23,444.7 mm2 (range: 16,229.1–32,490.0). The V/d value in the control group with the absence of accessory renal artery was found to be 19,717.15 mm2 (range: 13,704.6–28,000.0). The mean values in the two groups showed a statistically significant difference in the V/d with a P value of 0.001 (P < 0.05).

Conclusion:

The study suggests that the possibility of the presence of the accessory renal artery is directly proportional to the total renal volume and inversely proportional to the diameter of mRA. The use of integrated volumetric parameter (V/d) is therefore likely to play a key role in the prediction of the presence of accessory renal artery on imaging studies. Renal volumetry on CT angiography may help predict the presence of accessory renal artery and thus may have implications on renal Doppler studies.
A Primary Care Provider’s Guide to Management of Neurogenic Lower Urinary Tract Dysfunction and Urinary Tract Infection After Spinal Cord Injury
Authors: Milligan James , Goetz Lance L. , Kennelly Michael J.
Published: October 2020

Neurogenic lower urinary tract dysfunction (NLUTD), previously termed neurogenic bladder dysfunction, is a common secondary complication of spinal cord injury (SCI). It is associated with significant morbidity, reduced quality of life, increased health care costs, and mortality. Primary care providers (PCPs) play an important role in optimizing urohealth over the life span. This article will review NLUTD in SCI, its complication, surveillance, and management. PCPs should be aware of SCI-related NLUTD, its complications, management, and surveillance recommendations, and when to refer to a specialist.
A Primary Care Provider’s Guide to Managing Respiratory Health in Subacute and Chronic Spinal Cord Injury
Authors: Reyes Maria Regina L. , Elmo Mary Jo , Menachem Brandon , Granda Sara Mercedes
Published: October 2020

Respiratory complications following spinal cord injury (SCI) have remained the leading cause of death across the lifespan and are one of the most common reasons for hospitalization. Complications from altered respiratory physiology after SCI include atelectasis, pneumonia, venous thromboembolic disease, and sleep-disordered breathing. The risk for complications is greater with higher SCI levels and severity, and mortality from pneumonia is heightened compared to the general population. Optimal primary care for individuals with SCI includes appropriate surveillance for SCI-specific respiratory disease, key preventive care including promotion of influenza immunization and respiratory muscle training, and early identification and treatment of pneumonia with institution of aggressive secretion management strategies. The respiratory physiology and specific management of respiratory complications after SCI is reviewed.
STUDIES IN INHERITANCE IN SUGAR CANE
Authors: Cowgill H. B.
Published: October 2020

Resumen en inglés.
THE MOTTLING DISEASE OF CANE AND THE SUGAR PRODUCTION OF PORTO RICO
Authors: Figueroa C. A.
Published: October 2020

Resumen en inglés.
INSECTS AND MOTTLING DISEASE
Authors: Graywood Smyth E.
Published: October 2020

Resumen en inglés.
DINÁMICA POBLACIONAL DE LA ALEVILLA DEL DORSO DE DIAMANTE, PLUTELLA XYLOSTELLA (L.) (LEPIDOPTERA: PLUTELLIDAE), EN REPOLLO BAJO CONDICIONES DE INTERCALADO, CONTROL BIOLÃ"GICO Y ASPERSIONES CON PRODUCTOS A BASE DE BT
Authors: Ángel L. González-Rodríguez  , Raúl Macchiavelli
Published: October 2020

Se realizó un estudio (1998-99) en la Subestación Experimental Agrícola de Juana Díaz (EEA-UPR) para determinar la dinámica poblacional de Plutella xylostella (L.) en repollo de monocultivo y en dicultivos sustitutivos tipo relevo de repollo/tomate o repollo/wedelia. En 1998, se crearon subparcelas tratando la mitad de las parcelas principales con productos a base de Bt. Todos los tratamientos se asperjaron con Bt en 1999 excepto por las parcelas del control en monocultivo. Se liberaron avispillas de Cotesia plutellae Kurdjumov, un parasitoide de larvas de P. xylostella, para el control biológico por inundación. El tomate como planta acompañante mostró una tendencia a reducir las poblaciones de P. xylostella, redujo el parasitismo por C. plutellae y compitió con el repollo causando la producción de cabezas más pequeñas y menos numerosas en el policultivo. Las aspersiones con Bt redujeron la densidad poblacional de P. xylostella, pero éstas permanecieron por encima de 0.5 larvas por planta durante las etapas críticas de acopamiento y desarrollo de las cabezas, permitiendo así daños cosméticos a la cabeza. El parasitismo por C. plutellae fue de 65.3 y 11.6% en el monocultivo sin Bt en 1998 y 1999, respectivamente. El parasitoide no pudo regular el crecimiento poblacional de su hospedero en este estudio. La leguminosa Crotalaria juncea, utilizada como borde, no mejoró el parasitismo por C. plutellae. Se discute la interpretación y aplicación de los resultados.
NEW RECORDS OF NATURAL ENEMIES OF THE PEPPER WEEVIL, ANTHONOMUS EUGENII CANO (COLEOPTERA: CURCULIONIDAE), IN PUERTO RICO
Authors: Eduardo Correa-Galíndez  , Arístides Armstrong  , Carlos Cruz  , Edwin Abreu
Published: October 2020

Two parasitoid species (Catolaccus hunteri and Urosigalphus mexicanus) were recovered from the larvae of A. eugenii from samples collected at Lajas, Puerto Rico.