bluuebunny/crossref_metadata_2025 huggingface dataset:
Ophthalmic Artery Occlusion and Subsequent Retinal Fibrosis From a Calcium Hydroxylapatite Filler Injection
Authors: Oh Daniel J. , Jiang Yi , Mieler William F.
Published: April 2019

Purpose:

We report a case of an otherwise healthy 48-year-old woman presenting with acute vision loss after injection of a soft-tissue filler in the glabellar region with calcium hydroxylapatite microspheres (Radiesse, Merz North America, Inc) with 9 months of follow-up.

Methods:

Fundus photographs and spectral-domain optical coherence tomography (SD-OCT) were obtained at presentation, at 4 months of follow-up, and at 9 months of follow-up.

Results:

Acutely, the retina was characterized by significant pallor and thickening but evolved into diffuse retinal fibrosis and atrophy. The patient had no light perception at presentation and did not recover any visual function.

Conclusions:

Few case reports have described calcium hydroxylapatite filler injections leading to orbital and ocular complications. This is the first case report illustrating dense fibrotic and atrophic retinal changes on fundus photography, fluorescein angiography, and SD-OCT. While various facial fillers have been reported to have serious ocular consequences, we illustrate the acute and subsequent sequelae of an ophthalmic artery occlusion from calcium hydroxylapatite microspheres.
Clinical Effectiveness of Switching Between Ranibizumab and Aflibercept in Treatment of Neovascular AMD: US Real-World Outcomes
Authors: Dugel Pravin U. , Griner Raymond , Ferreira Alberto , Milnes Fran , Lotery Andrew J.
Published: April 2019

Purpose:

The purpose of this article is to examine visual acuity (VA) outcomes and treatment patterns in neovascular age-related macular degeneration (nAMD) eyes switching between ranibizumab and aflibercept in routine clinical practice.

Methods:

Electronic medical records were used to identify nAMD eyes receiving ranibizumab or aflibercept with 12 months’ follow-up since switching antivascular endothelial growth factor (anti-VEGF) therapy. The primary outcome compared mean change in VA between switch and Month 12 to test the noninferiority of switching from ranibizumab to aflibercept vs aflibercept to ranibizumab. Comparing the number of injection/noninjection visits was the key secondary objective.

Results:

A total of 269 eyes switching from ranibizumab to aflibercept and 83 switching from aflibercept to ranibizumab were included. The mean change in VA (letters) after 12 months in eyes switched from ranibizumab to aflibercept, and from aflibercept to ranibizumab, was –1.56 and 0.21, respectively ( P = .65). The adjusted difference (95% confidence interval) of mean change at Month 12 was 1.29 (–2.97 to 5.55; P = .55), confirming the noninferiority of ranibizumab. The mean (±SD) number of injections during follow-up was 8.67 (±2.63) for eyes switching from aflibercept to ranibizumab and 7.79 (±2.77) for ranibizumab to aflibercept ( P = .01).

Conclusions:

Switching between anti-VEGFs is not associated with clinically relevant differences in VA at 12 months in routine clinical practice.
A preliminary study of the multilingual dictionary Gujin Shilin (Kokeum Seklim) of the Joseon Dynasty: Its compilation background, structure, content and value
Authors: Lee Kyeongwon , Yurn Gyudong , Lee Sujin , Kim Taewoo
Published: April 2019

Gujin Shilin 古今释林 is a multilingual dictionary, published in 1789 by Yi Ui-Pong (李义凤). The initial motivation for publishing the book was to supplement the incompleteness of other commentary books on Zhuzi Yulei 朱子语类, including Yi Hwang’s (李滉) Yulujie 语录解. At last, Yi Ui-Pong completed his project as an unabridged encyclopedia of East Asian languages based on more than 1500 Jingshiziji 经史子集 (classics, history, philosophy and collections of belle letters) of China and Korea. The book has been understudied because of its enormous number of entries, its inaccessibility due to the many languages used within, and its lack of readability due to typos and variant letters. Therefore, the goal of the present paper is to analyze the background of the publication of Gujin Shilin, and its structure, content and research value. Gujin Shilin contains vocabulary from Mongolian, Manchu, Japanese, Vietnamese, Thai as well as Korean and Chinese from different historical periods. These can be used as invaluable data for the study of international studies involved in each field, including the phonological changes that the Asian languages have gone through, the interrelation among Asian languages and their mutual influences, the linguistic life, culture and custom shared by the ‘Chinese character cultural sphere’ countries and the study of the variant Chinese characters.
Navigating Social Relationships with Mentors and Peers: Comfort and Belonging among Men and Women in STEM Summer Research Programs
Authors: Daniels Heather A. , Grineski Sara E. , Collins Timothy W. , Frederick Angela H.
Published: April 2019

Gender disparities in science, technology, engineering, and mathematics (STEM) are well documented, yet little is known about how women and men students establish social relationships with research mentors and peers and how that shapes their experiences in STEM. We conducted a series of interviews with 17 undergraduate students from a Hispanic majority institution regarding their participation in STEM-focused summer research programs at nine universities. Differences in levels of comfort in relationships were present when comparing men and women. Women students expressed comfort in relationships with mentors who provided psychosocial mentoring, were available to answer questions, and were of the same gender; they expressed some social discomfort in informal interactions with mentors. Men students felt comfortable with mentors who provided limited guidance, little psychosocial mentoring, and opportunities for informal interactions. In terms of peer relationships, women sought out the confidence of a few similar peers, while men were comfortable with a wide variety of peers. Men’s greater comfort with social relationships seemed to reflect their affinity with the masculine-dominated culture of STEM. For women, cultivating safe spaces through relationships with supportive peers and working with same-gender faculty mentors seemed to mitigate some of the discomforting aspects of their STEM research experiences.
Inclusive Teaching
Authors: Dewsbury Bryan , Brame Cynthia J.
Published: April 2019

Over the past two decades, science, technology, engineering, and mathematics (STEM) faculty have been striving to make their teaching practices more inclusive and welcoming to the variety of students who enter college. However, many STEM faculty, even those at teaching-focused institutions, have been educated in a traditional environment that emphasizes research and may not include classroom teaching. This can produce a deficit in training that leaves many STEM faculty feeling uncertain about inclusive teaching practices and their essential undergirding principles. This essay describes an online, evidence-based teaching guide ( https://lse.ascb.org/evidence-based-teaching-guides/inclusive-teaching ) intended to help fill this gap, serving as a resource for science faculty as they work to become more inclusive, particular with regard to differences in race, ethnicity, and gender. The guide describes the importance of developing self-awareness and empathy for students as a precursor to considering classroom practices. It also explores the role of classroom climate before turning to pedagogical choices that can support students’ sense of belonging, competence, and interest in the course. Finally, the guide suggests that true inclusivity is a community effort and that instructors should leverage local and national networks to maximize student learning and inclusion. Each of these essential points is supported by summaries of and links to articles that can inform these choices. The guide also includes an instructor checklist that offers a concise summary of key points with actionable steps that can guide instructors as they work toward a more inclusive practice. We hope that the guide will provide value for both faculty who are just beginning to consider how to change their teaching practices and faculty seeking to enrich their current efforts.
GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73
Authors: Lalioti Maria-Eleni , Arbi Marina , Loukas Ioannis , Kaplani Konstantina , Kalogeropoulou Argyro , Lokka Georgia , Kyrousi Christina , Mizi Athanasia , Georgomanolis Theodore , Josipovic Natasa , Gkikas Dimitrios , Benes Vladimir , Politis Panagiotis K. , Papantonis Argyris , Lygerou Zoi , Taraviras Stavros
Published: April 2019

A distinct combination of transcription factors elicits the acquisition of a specific fate and the initiation of a differentiation program. Multiciliated cells (MCCs) are a specialized type of epithelial cells that possess dozens of motile cilia on their apical surface. Defects in cilia function have been associated with ciliopathies that affect many organs, including brain and airway epithelium. Here we show that the geminin coiled-coil domain-containing protein 1 GemC1 (also known as Lynkeas) regulates the transcriptional activation of p73, a transcription factor central to multiciliogenesis. Moreover, we show that GemC1 acts in a trimeric complex with transcription factor E2F5 and tumor protein p73 (officially known as TP73), and that this complex is important for the activation of the p73 promoter. We also provide in vivo evidence that GemC1 is necessary for p73 expression in different multiciliated epithelia. We further show that GemC1 regulates multiciliogenesis through the control of chromatin organization, and the epigenetic marks/tags of p73 and Foxj1. Our results highlight novel signaling cues involved in the commitment program of MCCs across species and tissues.

This article has an associated First Person interview with the first author of the paper.
The gastric sieve of penaeid shrimp species is a sub-micron nutrient filter
Authors: Pattarayingsakul Werawich , Pudgerd Arnon , Munkongwongsiri Natthinee , Vanichviriyakit Rapeepun , Chaijarasphong Thawatchai , Thitamadee Siripong , Kruangkum Thanapong
Published: April 2019

Unlike vertebrates, the penaeid shrimp stomach is of ectodermic origin and is thus covered by a cuticle that is sloughed upon molting. It is composed of two chambers, here called the anterior and posterior stomach chambers, ASC and PSC respectively. The PSC contains a filtration structure variously called a pyloric filter, filter press, gastric filter or gastric sieve (GS) and the latter will be used here. The GS resembles an elongated, inverted-V, dome-like, chitinous structure with a midline ridge that is integral to the ventral base of the PSC. The dome surface is covered with a carpet-like layer of minute, comb-like setae bearing laterally-branching setulae. This carpet serves as a selective filter that excludes large partially-digested food particles but allows smaller particles and soluble materials to enter hepatopancreatic ducts that conduct them into the shrimp hepatopancreas (HP) where further digestion and absorption of nutrients takes place. Although the GS function is well known, its exclusion limit for particulate material has not been clearly defined. Using histological and ultra-structure analysis, we show that the GS sieve pore diameter is approximately 0.2-0.7 μm in size, indicating a size exclusion limit (SEL) of substantially less than 1 μm. Using fluorescent microbeads we show that particles of 1 μm diameter could not pass the GS but that those 0.1 μm diameter did pass through to accumulate in longitudinal grooves and move onto the HP where some were internalized by tubule epithelial cells. We found no significant differences in these sizes between the species Penaeus monodon and Penaeus vannamei or between juveniles and adults in P. vannamei. This information will be of value for design of particulate feed ingredients such as nutrients, therapeutic drugs and toxin-absorbing materials that may selectively target the stomach, intestine or HP of cultivated shrimp.
HIV, syphilis and hepatitis B coinfections in Mkushi, Zambia: a cross-sectional study
Authors: Katamba Cibangu , Chungu Theresa , Lusale Chisali
Published: April 2019

Background: Human immunodeficiency virus, syphilis and hepatitis B virus (HBV) are major global public health problems. They are sexually transmitted diseases with overlapping modes of transmission and affected populations. The aim of this study is to assess the seroprevalence of HIV 1, hepatitis B virus and syphilis coinfections among newly diagnosed HIV individuals aged 16 to 65 years, initiating on antiretroviral therapy, in Mkushi, Zambia.

Methods: A total number of 126 sera were collected from HIV 1 infected patients attending Mkushi district hospital/ART clinic for antiretroviral therapy initiation. Hepatitis B surface antigen test and serologic test for syphilis were conducted between March and May 2018.

Results: Of the 126 participants, hepatitis B surface antigen (HBsAg) was detected with a prevalence of 9.5% among newly diagnosed HIV infected patients, while that of syphilis was as high as 40.5% in this same population group. Three patients recorded HIV coinfections with both syphilis and hepatitis B virus (2.4%) at the same time. After analysis, the results indicate that there was no significant association between gender for both dependent variables: HIV/syphilis or HIV/hepatitis B virus coinfections (alpha significance level > 0.05). Those who had a history of syphilis infection in the past were more likely than those who had none to be HIV-syphilis coinfected (53.6% vs 34%, respectively; odd ratio [OR] 2.236; 95% confidence interval [CI] 1.045 – 4.782).

Conclusion: The high prevalence rates for HIV, HBV, and syphilis coinfections strongly indicate the need for HBV and syphilis screening for HIV infected individuals. Furthermore, the high number of patients previously treated for syphilis who retest positive for syphilis in this study calls for use of the Venereal Disease Research Laboratory test to identify true syphilis infection (titers ≥ 1:8 dilutions, strongly suggestive).
Understanding the role of neutrophils in chronic inflammatory airway disease
Authors: Jasper Alice E , McIver William J , Sapey Elizabeth , Walton Georgia M
Published: April 2019

Airway neutrophilia is a common feature of many chronic inflammatory lung diseases and is associated with disease progression, often regardless of the initiating cause. Neutrophils and their products are thought to be key mediators of the inflammatory changes in the airways of patients with chronic obstructive pulmonary disease (COPD) and have been shown to cause many of the pathological features associated with disease, including emphysema and mucus hypersecretion. Patients with COPD also have high rates of bacterial colonisation and recurrent infective exacerbations, suggesting that neutrophil host defence mechanisms are impaired, a concept supported by studies showing alterations to neutrophil migration, degranulation and reactive oxygen species production in cells isolated from patients with COPD. Although the role of neutrophils is best described in COPD, many of the pathological features of this disease are not unique to COPD and also feature in other chronic inflammatory airway diseases, including asthma, cystic fibrosis, alpha-1 anti-trypsin deficiency, and bronchiectasis. There is increasing evidence for immune cell dysfunction contributing to inflammation in many of these diseases, focusing interest on the neutrophil as a key driver of pulmonary inflammation and a potential therapeutic target than spans diseases. This review discusses the evidence for neutrophilic involvement in COPD and also considers their roles in alpha-1 anti-trypsin deficiency, bronchiectasis, asthma, and cystic fibrosis. We provide an in-depth assessment of the role of the neutrophil in each of these conditions, exploring recent advances in understanding, and finally discussing the possibility of common mechanisms across diseases.
Recent developments in psychosocial interventions for borderline personality disorder
Authors: Temes Christina M , Zanarini Mary C
Published: April 2019

Borderline personality disorder (BPD) is a serious psychiatric disorder that affects multiple symptomatic domains and is associated with an increased risk of suicidality. Several empirically supported treatments for BPD have been developed in recent years for adults with BPD. More recent work has focused on tailoring or applying (or both) these existing treatments to specific patient populations, including patients with certain types of comorbidity (for example, BPD and post-traumatic stress disorder or antisocial personality disorder) and younger patients. Other work has involved developing treatments and models of treatment delivery that address concerns related to access of care. Relatedly, new adjunctive and technology-assisted interventions have been developed, adding to the growing repertoire of treatment options for these patients. Advances in the last several years address specific treatment needs and offer cost-efficient options for this diverse patient population.
Human aldose reductase unfolds through an intermediate.
Authors: Sekhon Gurprit , Singh Ranvir
Published: April 2019

Background: Human aldose reductase (hAR) converts glucose to sorbitol under hyperglycemic conditions. Aldose reductase is first and rate limiting enzyme of polyol pathway. Under hyperglycemia, increased flux of glucose through this pathway has been implicated in development of secondary complication in diabetes. Due to this clinical implication, aldose reductase attracted considerable attention from drug discovery perspective. In spite of extensive characterization of the biochemical and structural context, little is known about the unfolding behavior of aldose reductase. This study reports equilibrium unfolding studies of human aldose reductase.

Methods: We carried out thermal and chemical induced equilibrium unfolding studies of human aldose reductase monitored by circular dichroism and tryptophan and ANS fluorescence spectroscopy. 

Results: Thermal unfolding studies present a classical picture of two state unfolding from native to unfolded state. The data was used to derive thermodynamic parameters and study thermostability of aldose reductase. Urea and GuHCl induced equilibrium unfolding studies led us to discover an intermediate state, which gets populated at 3.5-4.0 M and 0.7-2 M of urea and GuHCl, respectively. Thermodynamic parameters from chemical induced unfolding are in agreement with those obtained from thermal unfolding.

Conclusion: This study revealed that aldose reductase unfolds from native to unfolded state via an intermediate. Assessment of thermodynamic stability of native, intermediate and unfolded state shows that three states are separated by significant energy barriers that ensure cooperativity of unfolding. As hAR functions in cells which are under osmotic and oxidative stress, these in vitro findings may have implications for its native conformation under physiological state.
Requirements elicitation for a blockchain vaccine supply chain management web/mobile application
Authors: Mindila Agnes N. , Wafula Joseph M. , Ratemo Harriet A. M. , Tabu Collins , Charo Joyce , Silali Catherine
Published: April 2019

Background: This paper presents the processes carried out to be able to develop/gather the complete and right requirements to developing a secure and effective blockchain system for the vaccine supply chain. The paper hence presents the requirements elicitation activity of the Blockchain web/mobile application for vaccine supply chain.

Methods: A mixed-methods methodology was applied. The methods employed were; document review, survey, focus group workshops, interviews, observation, brainstorming, brainwriting Unified Modeling Language and system dynamics.

Results: The paper present results of each of the methods used in requirements elicitation for eight themes, namely: temperature monitoring; quality, suitability and capacity of transport facilities; information systems and supportive management functions; storage quality, suitability and capacity; maintenance of cold-chain equipment; vaccine distribution; vaccine management policies and stock management. The results presented gave understanding of the operation of the existing vaccine supply chain and the requirements for the blockchain web/mobile application for vaccine supply chain. 

Conclusions: The requirements for the development of the desired vaccine supply chain web/mobile application were captured and documented.
Monitoring and forecasting of socio-economic development of regions based on the analysis of satellite images (on the example of solid waste disposal facilities and their impact on the environment)
Authors: Казарян Маретта , Kazaryan Maretta , Рихтер Андрей , Rihter Andrey , Шахраманьян Михаил , Shahraman'yan Mihail , Недков Румен , Nedkov Rumen
Published: April 2019

The object of research in this monograph is the objects of waste disposal (reduced OZO), simply put, garbage dumps, which are studied by space monitoring methods through digital processing of space images (concepts and approaches, techniques and models, programs and algorithms, educational guidelines, etc. d.). At the same time, the described approaches can be applied not only to OZO, but also to the majority of other objects on the earth's surface, therefore OZO are considered as examples of their applicability.
The monograph discloses the idea of using space information as a tool for monitoring the socio-economic development of the country.
The book is of interest to scientists and specialists in the field of geoinformatics, geophysics, regional economics, as well as for a wide range of readers.
The book can be used as an educational tool for teachers, students and specialists in space monitoring, practical image processing, problems of solid household and industrial waste as one of the basic factors for the development of the socio-economic structure of the state.
Chrześcijańskie braterstwo w świeckim społeczeństwie. Refleksje na podstawie nauczania Josepha Ratzingera
Authors: Łużyński Wiesław
Published: April 2019

Podstawowe wartości współczesnych społeczeństw, takie jak godność i prawa człowieka, równość, solidarność i sprawiedliwość, wyrosły z chrześcijaństwa. Braterstwo również należy do tych wartości, a jego źródłem jest Ewangelia Chrystusa. Według interpretacji J. Ratzingera, jest to wezwanie do opuszczenia naszego własnego ja i zwrócenia się do wspólnoty kościelnej, ponieważ chrześcijaństwo polega na „byciu dla innych”. Chrześcijanie uczą się braterstwa w Kościele, parafiach i wspólnotach apostolskich. Służą innym, ucząc ich braterstwa poprzez misję i zaproszenie dla braterskiej wspólnoty oraz poprzez agape i cierpienie. Chrześcijaństwo wnosi do wspólnoty obywatelskiej teologicznie uzasadnioną ideę braterstwa i doświadczenia wspólnoty w strukturach kościelnych.
Reminiscência e metafísica em Platão
Authors: Trabattoni Franco
Published: April 2019

Nos mais recentes debates críticos acerca da filosofia de Platão, a doutrina da reminiscência tem suscitado um interesse comparativamente menor em relação aos outros temas tratados na obra do pensador ateniense. Grande parte dos estudiosos modernos tende a considerar a reminiscência um método de pesquisa, bem como a marginalizar a referência a dois mundos e o trânsito da alma entre eles. O que pretendo demonstrar neste artigo é que não só a teoria da reminiscência é a condição de possibilidade necessária das nossas operações cognitivas (e não um método de pesquisa), como também o é apenas e só em virtude da sua valência metafísica.
‘Sex Trafficking’ as Epistemic Violence
Authors: Chapman-Schmidt Ben
Published: April 2019

While the American Allow States and Victims to Fight Online Sex Trafficking Act of 2017 (FOSTA) has been heavily criticised by researchers and activists for the harm it inflicts on sex workers, many of these critics nevertheless agree with the Act’s goal of fighting sex trafficking online. This paper, however, argues that in American legal discourse, ‘sex trafficking’ refers not to human trafficking for sexual exploitation, but rather to all forms of sex work. As such, the law’s punitive treatment of sex workers needs to be understood as the law’s purpose, rather than an unfortunate side effect. This paper also demonstrates how the discourse of ‘sex trafficking’ is itself a form of epistemic violence that silences sex workers and leaves them vulnerable to abuse, with FOSTA serving to broaden the scope of this violence. The paper concludes by highlighting ways journalists and academic researchers can avoid becoming complicit in this violence.
A criação de Institutos de Educação no Brasil como parte de uma história conectada da formação de professores
Authors: Vidal Diana Gonçalves , Rabelo Rafaela Silva
Published: April 2019

O presente artigo tem como objetivo discorrer sobre o papel tanto da New Education Fellowship (NEF) quanto do Teachers College (TC) da Columbia University como centros de legitimação da educação enquanto campo acadêmico emergente e como epicentros de redes de trabalho na educação. Para tanto, exploramos a constituição dos Institutos de Educação do Rio de Janeiro e de São Paulo nos anos 1930 entrelaçada ao movimento da Educação Nova, buscando evidenciar conexões, perscrutando a circulação de sujeitos e ideias no que podemos considerar uma história conectada da formação de professores. Baseamo-nos em bibliografia correlata e em fontes tais como revistas pedagógicas, programas de ensino e relatórios. A discussão aponta para uma trama de relações que interligava sujeitos e lugares nos anos 1920 e 1930, desempenhada por instituições como a NEF e o TC, que se constituíam em territórios sociais e epistemológicos congregados sobre a produção de repertórios acerca da Educação Nova.
Modernidade e minorias religiosas. Os arquivos da Igreja Lusitana (séculos XIX-XX)
Authors: Afonso José António , Silva António Manuel S. P.
Published: April 2019

A emergência em Portugal de correntes religiosas de matriz anglicana ao longo do século XIX corporizou-se, a partir de 1880, na Igreja Lusitana Católica Apostólica Evangélica, uma confissão religiosa formada do encontro de um conjunto de clérigos católicos insatisfeitos com o rumo doutrinal e a praxis litúrgica, pastoral e social da Igreja Católica Romana com movimentos protestantes e evangélicos que entretanto germinavam em vários pontos do País. Escorada nesta identidade de transição, a Igreja Lusitana pautou a sua atuação por forte investimento na educação popular e na criação de dispositivos promotores do ensino, do estímulo ao livre pensamento e da socialização assente nos princípios cristãos mas também de uma cidadania consciente e interventiva. Neste texto pretendemos, por um lado, apresentar, em termos genéricos, os fundos arquivísticos da Igreja Lusitana conservados, a par de uma importante hemeroteca e biblioteca históricas, e, por outro lado, apresentar o processo de criação do Arquivo Histórico desta igreja, evidenciando os constrangimentos e os resultados conseguidos até ao presente, salientando, deste modo, a sua crescente importância e valorização para o estudo e compreensão do papel das minorias religiosas na construção da modernidade.
Methodo Penido: estado e município na luta pela alfabetização na sociedade de Minas Gerais, no final do século XIX
Authors: Gonçalves Neto Wenceslau , De Carvalho Carlos Henrique
Published: April 2019

A partir da década de 1890, em Minas Gerais, observa-se preocupação governamental com a instrução pública, tentando superar o analfabetismo e criar estrutura para o progresso da educação, com edição da lei de instrução pública (1892) e do regulamento escolar (1893). Estimulou-se também outras práticas, como a publicação do Methodo Penido, de Agostinho Penido, que foi publicado em 1890 e largamente distribuído entre as escolas mineiras. No entanto, não se tem notícia de qualquer exemplar remanescente desse método e nem de estudos sobre seu autor. Foram utilizadas fontes do Arquivo Público Mineiro e do Arquivo Municipal de Ouro Preto. Buscou-se recuperar a trajetória de Agostinho Penido, do processo de avaliação, premiação e adoção do método por parte do governo e da difusão posterior do mesmo. Percebe-se a importância da alfabetização na sociedade mineira do início da República e a participação de intelectuais da educação na busca de alternativas para seu enfrentamento.
Saberes históricos prescritos na BNCC para o ensino fundamental: tensões e concessões /Historical knowledge prescribed at BNCC for elementary school: tensions and concessions
Authors: Franco Aléxia Pádua , Silva Junior Astrogildo Fernandes da , Guimarães Selva
Published: April 2019

O artigo analisa a configuração do ensino e aprendizagem de História na BNCC- Base Nacional Comum Curricular de História para o ensino fundamental em fase de implantação pelo Ministério da Educação nas redes de ensino do Brasil. Na introdução contextualizamos o processo de elaboração, as tensões e disputas políticas em torno da seleção dos conteúdos. Na sequencia refletimos sobre as prescrições do como e do que ensinar e, na ultima parte, analisamos o PNLD como um instrumento de politica pública que assume o papel de controle e cerceamento da autonomia docente no contexto escolar.PALAVRAS-CHAVE: História, currículo, ensino fundamental
Ensinar e aprender Geografia na Base Nacional Comum Curricular (BNCC) / Teaching and learning geography in the National Curriculum Common Base (BNCC)
Authors: Guimarães Iara Vieira
Published: April 2019

Neste artigo, realizamos uma discussão a respeito da configuração que a Geografia apresenta na Base Nacional Comum Curricular (BNCC). Nossa motivação é pautada tanto pela recente aprovação e homologação pelo Ministério da Educação do referido documento, quanto pelas questões que envolvem seu processo de debate e implementação junto aos professores atuantes nas escolas brasileiras. A delimitação do contexto político nacional em que foi construído o documento bem como a conotação de currículo presente no texto configuram o cenário sobre o qual levantamos questões para discussão e análise. Defendemos a importância de se considerarem os professores como os principais profissionais a serem consultados em qualquer política pública de ensino que intencione mudar as práticas pedagógicas, seus conteúdos curriculares, os materiais escolares e os processos de ensino-aprendizagem. Salientamos a especificidade da Geografia como componente curricular fundamental para a formação cidadã sendo, portanto, imprescindível em todos os segmentos da educação básica brasileira.PALAVRAS-CHAVES: Geografia Escolar. Currículo. Base Nacional Comum Curricular-BNCC.
A New Perspective on Neutrosophic Differential Equation
Authors: R.Sumathi I. , Mohana Priya V.
Published: April 2019

In this paper the Neutrosophic ordinary differential equation of first order via neutrosophic numbers is epitomized. We also intend to define the neutrosophic numbers and their (Î±, Î², Î³)-cut. Finally a numerical example is given to demonstrate its practicality andÂ Â Â Â Â Â Â Â Â Â Â Â  effectiveness of the differential equation involving neutrosophic numbers.Â
A Single Server Queue with Immediate Feedback, Working Vacation and Server Breakdown
Authors: M Varalakshmi , V M Chandrasekaran , M C Saravanarajan
Published: April 2019

This paper deals with analyze of a single server queueing system with immediate feedbacks and working vacation. Upon arrival if the customer sees the server to be busy then it joins the tail end of queue. Otherwise if server is idle, the customer gets into service. After completion of service, the customer is allowed to make an immediate feedback in finite number. Busy server may fail for a short interval of time. Using supplementary variable technique the steady state results are deduced. Some system performance measures are discussedÂ Â
A Statistical Study on Impact of Facebook Usage of Engineering Students at VIT
Authors: C Keerthika , Raghavan Manisha , V.M Chandrasekaran
Published: April 2019

This study aims to find the influence that Facebook plays as a social networking medium on engineering students at an undergraduate level in VIT, Vellore. Facebook, a prominent online social media and networking site was founded and launched in 2004 by Mark Zuckerberg. Facebook has been under the scanner to study the influence it has on human emotional health, social life and mental health. Facebook has grown to become one of the most prevalent Social Networking Sites (SNS) in this era. A lot of previous studies have tried to study the role Facebook has played not only on students or adolescents but also on adults and all. During this study, we have tried to see the role that Facebook plays in an engineering undergraduate student’s life especially the extent to which it affects the students’ academic performance. Various studies have shown that Facebook plays a major role in influencing emotions, moods and attitudes of students. We aim to understand the role that Facebook plays buy administering a survey amongst students in the University and analyse the extent to which students are affected by using it. The survey constituted of 16 questions and was administered to about 250 respondents belonging to the undergraduate engineering student pool. The method of sampling done was simple random sampling and data analysis was done using SPSS.
A Treatise on Ordinary Least Squares Estimation of Parameters of Linear Model
Authors: Mahaboob B. , Venkateswarlu B. , Narayana C. , Ravi sankar J. , Balasiddamuni P.
Published: April 2019

This research article primarily focuses on the estimation of parameters of a linear regression model by the method of ordinary least squares and depicts Gauss-Mark off theorem for linear estimation which is useful to find the BLUE of a linear parametric function of the classical linear regression model. A proof of generalized Gauss-Mark off theorem for linear estimation has been presented in this memoir.  Ordinary Least Squares (OLS) regression is one of the major techniques applied to analyse data and forms the basics of many other techniques, e.g. ANOVA and generalized linear models [1]. The use of this method can be extended with the use of dummy variable coding to include grouped explanatory variables [2] and data transformation models [3]. OLS regression is particularly powerful as it relatively easy to check the model assumption such as linearity, constant, variance and the effect of outliers using simple graphical methods [4]. J.T. Kilmer et.al [5] applied OLS method to evolutionary and studies of algometry.
A Treatise on Testing General Linear Hypothesis in Stochastic Linear Regression Model
Authors: Narayana C. , Mahaboob B. , Venkateswarlu B. , Ravi sankar J. , Balasiddamuni P.
Published: April 2019

The main objective of this research article is to propose test statistics for testing general linear hypothesis about parameters in stochastics linear regression model using studentized residuals, RLS estimates and unrestricted internally studentized residuals. In 1998, M. Celia Rodriguez -Campos et.al [1] introduced a new test statistics to test the hypothesis of a generalized linear model in a regression context with random design. Li Cai et.al [2] provide a new test statistic for testing linear hypothesis in an OLS regression model that not assume homoscedasticity. P. Balasiddamuni et.al [3] proposed some advanced tools for mathematical and stochastical modelling.
Detection of Epileptic Seizure Using Wavelet Analysis based Shannon Entropy, Logarithmic Energy Entropy and Support Vector Machine
Authors: Harlalka Vasudha , Pradip Puntambekar Viraj , Raviteja Kalugotla , Mahalakshmi P.
Published: April 2019

Epilepsy is a prevalent condition, mainly affecting the nervous system of the human body. Electroencephalogram (EEG) is used to evaluate and examine the seizures caused due to epilepsy. The issue of low precision and poor comprehensiveness is worked upon using dual tree- complex wavelet transform (DT-CWT), rather than discrete wavelet transform (DWT). Here, Logarithmic energy entropy (LogEn) and Shannon entropy (ShanEn) are taken as input features. These features are fed to Linear Support Vector MachineÂ Â Â Â  (L-SVM) Classifier. For LogEn, accuracy of 100% for A-E, 99.34% for AB-E, and 98.67% for AC-E is achieved. While ShanEn combinations give accuracy of 96.67% for AB-E and 95.5% for ABC-E. These results showcase that our methodology is suitable for overcoming the problem and can become an alternate option for clinical diagnosis.Â Â
An Improved Multiplication Algorithm
Authors: Subha S. , . .
Published: April 2019

Multiplication is commonly used arithmetic operation in computers. An algorithm is proposed to perform multiplication of positive numbers using law of indices. The two inputs  A and B are represented as binary numbers. Iteratively, the number A is multiplied with the bits in B. The coefficients of the partial products are accumulated. These coefficients are represented as binary numbers, the result coefficients are calculated. The proposed algorithm is simulated using Quartus 2 tool for two four bit inputs. An improvement in timing by 18%  with comparable power consumption and increased area is observed for input of four bits. The proposed algorithm can be extended for n-bit inputs.
Equitable Power Domination Number of Mycielskian of Certain Graphs
Authors: Banu Priya S. , Parthiban A. , Srinivasan N.
Published: April 2019

Let  be a simple graph with vertex set  and edge set . A set  is called a power dominating set (PDS), if every vertex   is observed by some vertices in  by using the following rules: (i) if a vertex  in  is in PDS, then it dominates itself and all the adjacent vertices of  and (ii) if an observed vertex  in   has  adjacent vertices and if   of these vertices are already observed, then the remaining one non-observed vertex is also observed by  in . A power dominating set    in   is said to be an equitable power dominating set (EPDS), if for every  there exists an adjacent vertex   such that the difference between the degree of  and degree of  is less than or equal to 1, i.e., . The minimum cardinality of an equitable power dominating set of  is called the equitable power domination number of  and denoted by . The Mycielskian of a graph  is the graph  with vertex set  where , and edge set  In this paper we investigate the equitable power domination number of Mycielskian of certain graphs.
Energy Potent Shortcut Tree Routing in Zigbee Networks
Authors: Rajeshkanna B. , Anitha M.
Published: April 2019

ZigBee is an international standard for low-power and low-data rate WPAN. ZigBee works on IEEE 802.15.4 MAC and physical layers. Its network layer is liable to facilitate routing in networks. To provide a near optimal routing path as well as to balance the load and energy over the nodes, Energy-efficient shortcut tree routing (ESTR) protocol suggested an optimization method with three criteria such as minimum hop-counts, minimum congestion and maximum link quality. This paper proposes an Energy potent shortcut tree routing (EPSTR) that adds one more criterion called minimum failure-transmissions with EPSTR’s criteria. The values for these criteria can be derived from the neighbor table data of a node. Performance evaluation reveals that EPSTR appreciably expands the network lifetime and shows better routing performances compared to ESTR.
On WS Closed and WS Open Maps in Topological Spaces
Authors: A Sajjanar Veeresha , M. Ittanagi Basavaraj
Published: April 2019

New type of closed and open maps called ws-closed and ws-open maps in topological spaces are introduced and studied. During this process some of their properties have been investigated. Also we introduce ws*-closed and ws*-open maps in topological spaces and discuss some properties.
Performance Comparison of Routing Protocols for Underwater Sensor Networks
Authors: Memon Komal , Bohra Nafeesa , K Shaikh Faisal
Published: April 2019

There is a great demand of an Underwater Sensor Networks (UWSNs) in applications of water monitoring and offshore exploration. In such applications, network comprises of multiple sensor nodes which are deployed at different locations and depths of water. Sensor nodes perform collective tasks such as data collection and data transmission to other nodes or Base Station (BS). The bottom nodes are located at depth of water, and are not able to communicate directly with the surface level nodes, these nodes require multi-hop communication with appropriate routing protocol. Therefore, an energy efficient routing protocols are used for such scenarios, which is necessary as well as challenging task. As sensors are battery operated devices, which are really problematic to recharge or replace. The error and propagation path delays are high in acoustic channels therefore underwater communication is much effected. Realizing the circumstances, more attention has been given to compare energy efficient routing protocols which comparatively consume low energy and achieve high throughput. This paper, comprises of analysis and comparison of existing UWSN based efficient energy routing protocols. Based upon the analysis and comparison, VBF and DBR have been proposed that fulfill the requirements. The analysis is done on NS-2 and for comparison, the performance metrics which are evaluated are: Packet delivery Ratio (PDR), energy consumption, throughput and average End to End (E2E) delay. The results show that VBF protocol consume very large amount of energy as compared to DBR protocol. Whereas DBR protocol have characteristics like low energy consumption, minimum delay high PDR and high throughput than VBF protocol.
Ethnic Conflict and Economic Cooperation in the Borderlands: Burma, Thailand, and the Karen
Authors: Siriyanun Sirinya , Tipparat Bubpasiri Dr.
Published: April 2019

Since 1949, the Karen ethnic minority has been engaged in an armed uprising against the Burmese government, and this uprising has defined Thai-Burmese border relations. Despite its length and impact, this conflict is easily overlooked, and has been willfully ignored by Thailand, Burma, and the international community in the optimism surrounding the start of the ASEAN Economic Community. Documentary research and interviews with participants in the conflict demonstrate that the Karen, and the armed nonstate groups which represent them, maintain the ability to end any sustained cross-border cooperation between Thailand and Burma. As such, a resolution to the conflict is necessary if the ASEAN Economic Community, and the various other projects that Thailand and Burma have envisioned for the border region, is to succeed.
Crop Recommender System for the Farmers using Mamdani Fuzzy Inference Model
Authors: Kuanr Madhusree , Kesari Rath Bikram , Nandan Mohanty Sachi
Published: April 2019

Recommender systems provide suggestions to the users for choosing particular items from a large pool of items. The purpose of this study is to design a collaborative recommender system for the farmers for recommending giving prior idea regarding a crop which is suitable according to the location of the farmer based on weather condition of the previous months. The proposed system also recommends other seeds, pesticides and instruments according to the preferences in farming and location of the farmers while purchasing the seeds through online. It uses cosine similarity measure to find the similar user according the location of the farmer and fuzzy logic for predicting the yield of rice crop for Kharif season in state Odisha, India. The proposed system is implemented in Mamdani Fuzzy Inference model. The results reveal that it provides prior idea regarding a crop before sowing of seeds.Â Â
A Survey of User Preferences on Biometric Authentication for Smartphones
Authors: Syabila Zabidi Nur , Mohd Norowi Noris , Wirza O.K. Rahmat Rahmita
Published: April 2019

The search for improving users’ security needs, awareness and concerns in the context of mobile phones still has been conducting in today’s society. Biometric systems identify a person or verify the identity of a person using purportedly unique physical traits or behaviour of that individual. In order to understand user requirements for biometric authentication, it is important to focus on several key issues, including the importance of smartphones in implementing biometric authentication, users’ general knowledge and perception towards biometric authentication, and users’ trust and practice when using different biometric technology for securing their smartphone’s data. A preliminary study in the form of an online survey was conducted. The idea of this study was to conduct a survey on users about their general knowledge and perceptions towards different biometric authentication on smartphones. The results of the study indicate that smartphone is an important tool in implementing biometric authentication. Moreover, users knew what biometric technology is and they are not reluctant to use them. Furthermore, users knew how to protect their smartphone’s data and practice the related preventions. The results are expected to give an insight of deploying biometric technology into mobile devices and further researching onto others biometric authentication.
Evaluation of Anaerobic Digester for Treating Tannery Effluent by Water Displacement Method
Authors: Sasivarman B. , Rajeshkannan M. , Sowmiya V. , Subashchandrabose E. , Swetha R.
Published: April 2019

At hand, be a lot of process to production of leather, such as soaking, liming, degreasing, pickling and tanning process. This makes huge quantity of waste water manufacture from tannery industry. Tannery effluents are additional cause to the environment. An Indian tannery industry generates the tannery effluent regarding 50,000 m3/ day. As a result, treating tannery effluent is the majority chief assignment to save the adjacent area and to get better fresh water. In this exploration the sample from the tanning industry waste water undergo Biological behavior development, typically tanning industry waste water is an effectual within the organichealingprogression. In this learningalongsideby means of the waste matter, the activated slush from Sewage Treatment Plant is additional as a seeding material in the proportion of 95%, 90%, 80%, 70%, 60%, 50%, replacein the 500ml serum bottle in addition to closed tightly to keep up Anaerobic situation and evaluate their biogas production day by day. The 60% activated sludge and the 40% tannery waste waters Mixture gave the high yield of biogas and degraded the macrobiotic contaminants efficiently. From this study, it is observed that activated Sludge is use as seeding materials to biodegrade the natural pollutant at hand in the tannery waste water.
Nominal Aggregate Size an Index to The Resilient Modulus Value of Hot Mix Asphalt
Authors: S. Neham Sahar
Published: April 2019

Properties and performance of hot mix asphalt are highly affected by aggregate as it is consists of 85 to 95 percent by weight and 75 to 85 percent by volume mineral aggregate. Resilient modulus was a very important parameter used either as input data in the procedure of pavement design or to evaluate the relative quality of materials. This research study the effect of nominal aggregate size on the resilient modulus value with different variations  such as tested temperature, percent of asphalt cement and filler content, load duration, and asphalt viscosity. Results under different variables showed that nominal aggregate size has a significant effect on the resilient modulus value as well as resilient modulus value decreases by (21.04% - 26.66%) when the nominal aggregate size increases from 19mm to 25mm while it decreases by (22.43 - 29.50%) when the nominal aggregate size increases from 25mm to 37.3mm.