bluuebunny/crossref_metadata_2025 huggingface dataset:
Minimally Invasive Method of Measuring Anti-Müllerian Hormone Level in Dried Blood Spots of Indonesian Infertile Population
Authors: Sini Ivan , Handayani Nining , Tjahjadi Ricky , Wulandari Tri Aprilliana , Afadlal Szeifoul , Polim Arie Adrianus , Sirait Batara , Suheimi Irham , Boediono Arief
Published: March 2024

This study aims to evaluate the certainty of anti-Müllerian hormone (AMH) levels in dried blood spots (DBS) compared to serum AMH. A total of 109 infertile women who planned to undergo their controlled ovarian stimulation cycle were recruited. Serum and DBS samples were collected from each patient for the quantification of AMH levels. Serum AMH was measured with an automated clinical chemistry assay (Roche) while DBS AMH was measured using the Ansh Labs DBS AMH ELISA reagent kit. Mean AMH level in DBS was [Formula: see text][Formula: see text]ng/mL, which ranged from 0.01 to 17.3[Formula: see text]ng/mL, while the mean AMH in serum samples was [Formula: see text][Formula: see text]ng/mL (0.01–10.8[Formula: see text]ng/mL). Comparable accuracy for low AMH quantification was observed between the two methods over basal antral follicle counts (AFC) as a clinical comparator (AUC 86%, cutoff [Formula: see text][Formula: see text]ng/mL, [Formula: see text], [Formula: see text] vs. 85%, cutoff [Formula: see text][Formula: see text]ng/mL, [Formula: see text], [Formula: see text], respectively for DBS and serum sample). Likewise, DBS AMH achieved high concordance for low AMH discrimination in comparison to serum AMH method (AUC 99% vs. 93%, respectively). A strong linear Spearman regression ([Formula: see text], [Formula: see text]) and sufficient agreement (94.5%, mean difference of −1.6, 2.7 to −5.9) was demonstrated among studied groups with mathematical Passing and Bablok regression equation of [Formula: see text]. The confidence interval of intercept (−0.12, 95% CI [−0.29 to −0.01]) and slope (1.80, 95% CI [1.66–1.94]) indicated a constant and proportional difference between the two methods but it was not significant ([Formula: see text]). AMH measurement in DBS could be useful as an alternative approach to screening ovarian reserve through a more convenient remote sample collection.
Resolving the Human-Subjects Status of ML's Crowdworkers
Authors: Kaushik Divyansh , Lipton Zachary C. , London Alex John
Published: March 2024

What ethical framework should govern the interaction of ML researchers and crowdworkers?
Towards Sustainability in Seed Supply for African Catfish, Clarias gariepinus (Burchell, 1822) Culture in Kenya: Lessons from Asian Catfishes Industry
Authors: Barasa James E. , Ouma Don Felix
Published: March 2024

The culture of African catfish, Clarias gariepinus, is constrained by the high mortality of fry, occasioning a shortage of high‐quality seeds for stocking by farmers. Asia, a continent with many success stories for aquaculture, leads in farmed production of some catfishes, a diverse group of 37 different families. Globally, the culture of catfishes ranks fifth in global farmed finfish production. Globally, Vietnam leads in the production and export of farmed striped catfish, Pangasianodon hypophthalmus, with 1,400,000 tonnes produced annually from about 7,000 hectares. Similarly, China farmed the non‐native Channel catfish, Ictalurus punctatus, into the major crop, with a current annual production of 250,000 tonnes. On the contrary, C. gariepinus, the main farmed catfish species in Africa, records low annual yields, with 240,000 tonnes for the whole continent. This paper explores the factors behind the high production of P. hypophthalmus and I. punctatus in Vietnam and China, respectively, and draws lessons for C. gariepinus farmers in Africa. Specifically, the use of differentiated hatchery and nursery husbandry practices was critical in boosting seed production, quantity, availability, and distribution for expanding the culture of P. hypophthalmus in Vietnam. Improvement of fish species through well‐designed genetic improvement programs helped China substantially increase production of I. punctatus. For both species, intensive fish production, as well as the adoption and implementation of suitable policies, increased seed production from hatcheries in both countries. These are discussed as some of the factors that spurred catfish production in the two Asian countries. We argue that if these are adopted by farmers in Africa, they could help improve the production of farmed C. gariepinus on the continent for food and nutrition security as well as generation of livelihood for local communities.
Figure S1 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

Figure S1. PBMC Antibody Staining Performance. (A, B) Histograms showing fluorescence intensity and cell counts when antibodies were used as single-color controls (SC; blue lines) overlaid with staining performance within the full antibody cocktail (multicolor, MC; black lines), in the T/B panel (A) and M/N/D panel (B). The same PBMC donor sample was used for (A and B) and data represent cells gated as singlets, non-RBC, live cells, and the appropriate lymphocyte or monocyte scatter gates. Data were normalized using the time gate to select equal numbers of cells for SC and MC for each marker.
FIGURE 3 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

BMC panel gating strategy. Density plots of the gating strategy used to identify indicated BMC cell types. Arrows denote sequential steps in the gating strategy and are used to visualize the relationships across populations. Canonically gated populations are indicated with brackets, while intermediate steps are indicated with parentheses. Data presented are derived from one representative sample and represent 72,000 CD45+ live single cells.
Supplementary Figure S3 from Identification of Nonfunctional Alternatively Spliced Isoforms of STING in Human Acute Myeloid Leukemia
Authors: Boda Akash R. , Liu Arthur J. , Castro-Pando Susana , Whitfield Benjamin T. , Molldrem Jeffrey J. , Al-Atrash Gheath , Di Francesco Maria Emilia , Jones Philip , Ager Casey R. , Curran Michael A.
Published: March 2024

Representative gating scheme for sorting HEK cells transduced with STING variants.
Soluble Biomarkers of Cerebrovascular Pathologies
Authors: Foley Kate E. , Wilcock Donna M.
Published: March 2024

Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins. With the advancement of imaging and pathological studies, we now understand that VCID is often comorbid with Alzheimer disease. While researchers in the Alzheimer disease field have been working for years to establish and test blood-based biomarkers for Alzheimer disease diagnosis, prognosis, clinical therapy discovery, and early detection, blood-based biomarkers for VCID are in their infancy and also face challenges. VCID is heterogeneous, comprising many different pathological entities (ischemic, or hemorrhagic), and spatial and temporal differences (acute or chronic). This review highlights pathways that are aiding the search for sensitive and specific blood-based cerebrovascular dysfunction markers, describes promising candidates, and explains ongoing initiatives to discover blood-based VCID biomarkers.
THE IMPACT OF TRADE OPENNESS ON INCOME INEQUALITY IN THE FORMER CENTRALLY PLANNED MIDDLE–INCOME ECONOMIES
Authors: Sarıgül Haşmet
Published: March 2024

This study investigates the association between trade openness and income inequality in the former centrally planned middle–income economies over the period 1994–2019. Apart from the full sample, the EU member or candidate middle–income Balkan economies, and the middle–income CIS countries subsamples were used in estimations as benchmark. Foreign direct investment, inflation, government expenditures and gross fixed capital formation control variables are incorporated into the PMG–ARDL model used in the study. Although some individual country or a few panel studies in the literature have investigated the relationship between trade openness and income inequality, to the best of our knowledge, none have examined these issues focusing on the middle–income post-communist economies and its subgroups particularly. The PMG estimation results for the sample including the middle–income Balkan economies reveal that within 1% increase of trade openness, income inequality worsens by 0.27. We suggest these countries to strengthen their income redistribution strategies while pursuing policies that promote integration into the global market.
Toda-Yamamoto Causality Test Between SMEs Loans And Economic Growth: Evidence From Turkiye
Authors: Özgün Fergül
Published: March 2024

In Turkey, SMEs make up the great majority of businesses. Due to their contributions to production, employment, innovation, and export, SMEs are crucial to the process of economic growth. Yet, SMEs' production operations are hampered by financial insufficiencies, which weaken the link between them and economic expansion. For SMEs, who must depend on external financing because of equity capital deficiencies, the loan system is crucial. With the use of Turkey as an example, this study examines the connection between SME loans and economic growth. Analysis was conducted for three different categories, namely loans extended to micro, small, and medium-sized enterprises. Quarterly data for the 2007Q1-2022Q2 period were considered and the Toda-Yamamoto causality test was used. It was determined that the causal relationship between SME loans and economic growth differs depending on the size of the enterprises. The relationship between loans extended to micro-enterprises and economic growth is unidirectional and the direction of the relationship is from growth to loans. Although there is a bidirectional relationship between loans extended to small enterprises and economic growth, it has been found that there is no causal relationship between loans extended to medium enterprises and economic growth.
Analyzing Dataset Annotation Quality Management in the Wild
Authors: Klie Jan-Christoph , Castilho Richard Eckart de , Gurevych Iryna
Published: March 2024

Data quality is crucial for training accurate, unbiased, and trustworthy machine learning models as well as for their correct evaluation. Recent work, however, has shown that even popular datasets used to train and evaluate state-of-the-art models contain a non-negligible amount of erroneous annotations, biases, or artifacts. While practices and guidelines regarding dataset creation projects exist, to our knowledge, large-scale analysis has yet to be performed on how quality management is conducted when creating natural language datasets and whether these recommendations are followed. Therefore, we first survey and summarize recommended quality management practices for dataset creation as described in the literature and provide suggestions for applying them. Then, we compile a corpus of 591 scientific publications introducing text datasets and annotate it for quality-related aspects, such as annotator management, agreement, adjudication, or data validation. Using these annotations, we then analyze how quality management is conducted in practice. A majority of the annotated publications apply good or excellent quality management. However, we deem the effort of 30% of the studies as only subpar. Our analysis also shows common errors, especially when using inter-annotator agreement and computing annotation error rates.
Cyrtandromoea sudhansui (Phrymaceae), a new species from Northeast India
Authors: CHOWLU KRISHNA , SHENOY AKSHATH , NURALIEV MAXIM S.
Published: March 2024

Cyrtandromoea sudhansui, a new species of Phrymaceae, is described and illustrated. The species was discovered in the Eastern Himalayas in 2023 during a botanical survey in Arunachal Pradesh, India. Cyrtandromoea sudhansui is unique within the genus in having blue corolla; it also differs from the other species of Cyrtandromoea in the following combination of morphological traits: winged stem, calyx ca. 1.5 cm long and hairy along ridges, hairy stamens, hairy ovary and style. The new species is assessed as Data Deficient according to the IUCN Red List criteria. The new discovery represents the second species of the genus known in the flora of India, and a new generic record for the state of Arunachal Pradesh and for the mainland India in general.
Three
Authors: Felsenstein Frank
Published: March 2024

A brief overview of Vera’s early years at school. This chapter features a couple of Vera’s journal entries, establishing further information about her education as she grew older and her feelings on her learning.
Four
Authors: Felsenstein Frank
Published: March 2024

An overview of Mope’s years at university, touching on personal familial conflicts and how this affected him in his academic career. This chapter also addresses Mope re-joining his family business.
Eighteen
Authors: Felsenstein Frank
Published: March 2024

Vera spends her summer at the Marks & Spencer staff summer camp, Mope moves into new lodgings due to having been evicted from his old ones. These factors, along with Mope’s passport being confiscated, and delays in their correspondence, lead to the frustration evident in the letters and journal entries. Eventually Mope’s passport is returned, and the two manage to meet up in Czechoslovakia.
Twenty-Two
Authors: Felsenstein Frank
Published: March 2024

Mope contacts the British consulate in the hope of settling in England while still preparing for his mother’s emigration to Palestine. The couple’s correspondence discusses details of their upcoming marriage.
Accuracy of Trauma Surgeons Prospective Estimation of the Injury Severity Score: A Pilot Study
Authors: Mlaver Eli , Meyer Courtney H. , Codner Jesse A. , Solomon Gina , Sharma Jyotirmay , Krause Morgan , Vassy W. Matthew , Dente Christopher J. , Todd S. Rob , Ayoung-Chee Patricia
Published: March 2024

Injury Severity Score (ISS) has limited utility as a prospective predictor of trauma outcomes as it is currently scored by abstractors post-discharge. This study aimed to determine accuracy of ISS estimation at time of admission. Attending trauma surgeons assessed the Abbreviated Injury Scale of each body region for patients admitted during their call, from which estimated ISS (eISS) was calculated. The eISS was considered concordant to abstracted ISS (aISS) if both were in the same category: mild (<9), moderate (9-15), severe (16-25), or critical (>25). Ten surgeons completed 132 surveys. Overall ISS concordance was 52.2%; 87.5%, 30.8%, 34.8%, and 61.7% for patients with mild, moderate, severe, and critical aISS, respectively; unweighted k = .36, weighted k = .69. This preliminarily supports attending trauma surgeons’ ability to predict severity of injury in real time, which has important clinical and research implications.
The Social Justice Core Practices of Philadelphia Educators: A Modified Delphi Study
Authors: Schiera Andrew J. , Carl Nicole Mittenfelner , Marshall-Butler Jasmine
Published: March 2024

To live justice-oriented commitments in teaching practice, approaches spanning Social Justice Teacher Education, the Core Practice Movement, and Context-specific Teacher Preparation might dovetail by identifying “social justice core practices” (SJCPs) novices learn to enact. At the intersection of the situated and critical perspectives underlying these three approaches, this study investigates the SJCPs of Philadelphia educators and how they characterize their contextuality. A modified Delphi study drawing on the expertise of 27 local social justice educators revealed group consensus on 13 SJCPs. Further qualitative analysis surfaced four patterns related to contextuality: SJCPs as responses to macrosociopolitical inequities, manifesting critical praxis; the role of school, district, and professional constraints; the need to situate and adapt SJCPs for the subject area and grade level; and the inseparability of identity and positionality from enactment. From this site-specific approach positioning local educators as experts, implications for teacher education’s role in shaping a more justice-oriented profession are discussed.
Cognitive Reserve and Frontotemporal Disorders: Exploring the Relationship Between Education, Physical Activity, and Cognitive Dysfunction in Older Adults
Authors: Amian Josue G. , Fernandez-Portero Cristina , de la Bella Rocío , Arenilla-Villalba María José , López-Lluch Guillermo , Alarcon David
Published: March 2024

In this study we investigated the relationship between cognitive reserve (CR) proxies, such as education, physical activity (PA), and cognitive dysfunction (CD) in the presence or absence of frontotemporal disorders (FTD). Previous research has suggested that education and PA may delay the onset of CD and reduce the risk of developing dementia. However, it remains unclear whether these CR proxies can protect against CD when FTD is present. We aimed to explore this relationship and determine whether sustained CR may be evident regardless of FTD. We recruited 149 older adults (aged 65–99 years) from community centers where they were voluntarily participating in leisure activities. We used bioelectrical impedance to measure their body composition, and we administered the International PA Questionnaire and the Mini-Mental State Examination to measure their PA and cognitive function, respectively. We used the Frontal Assessment Battery to screen for frontotemporal dementia. Our results showed that people with FTD were older, had lower education, and engaged in less PA, relative to other participants. Regression models revealed that age, education, and PA were significant predictors of FTD. More specifically, FTD was negatively associated with cognitive functioning, and there were significant interaction effects between FTD and education and PA. PA and education were significant predictors of cognitive functioning, and, when values for PA and education were high, they offset the effects of FTD on cognitive function. These findings support impressions that PA and years of education provide an insulating or compensatory effect on cognitive functioning in older adults with executive dysfunction or frontotemporal dementia, highlighting the importance of encouraging both pursuits.
A worthy investment? Investigating alumni perceptions of nonprofit degrees
Authors: Melville-Holder Jo’ann , Stewart Amanda J , Kuenzi Kerry , Walk Marlene , Russell Dylan , McGovern Shannon
Published: March 2024

As students invest in higher education, an assumption of value creation emerges as training and education are expected to yield career and compensation outcomes. Given the growth of nonprofit management education, we see merit in investigating how alumni perceive their degree in terms of the return on their investment of money and time. This study relies on survey data collected from the (project name redacted for anonymity), and joins the Project’s previous findings to elucidate how nonprofit management education is shaping the nonprofit sector’s workforce. Our findings highlight how nonprofit sector commitment, but not work in the sector, influences how graduate alumni view their degree, and that those carrying a higher financial burden from their degree view their degree less favorably. These findings inform administrators of nonprofit degree programs about how students perceive the value of their education and how that perception impacts nonprofit management education as a pipeline for the nonprofit workforce.
Shifting from Individual Opulence to Collective Well-Being: Replacing Luxury and Tourism as Human Stains by Nurturing a Positive Anthropocene
Authors: Cristini Hélène , Woodside Arch G. , Kauppinen-Räisänen Hannele
Published: March 2024

While prior research describes the transformation of luxury from a micro level with an individualistic focus to a macro level with a sustainable foundation, this study anticipates that a radical reconfiguration of individualistic-focused luxury and tourism to a meta level well-being perspective is necessary for nurturing a positive Anthropocene. Therefore, the study constructs the perspective that luxury and tourism can contribute to environmental and human well-being, which is transformative from an individualistic, dolce vita, luxury travel Zeitgeist (i.e., complementing Roth's tragedy, The Human Stain) to collective well-being that is authentic and holistically encompassing the entire ecosystem. The analyses here indicate that human attitudes, beliefs, and actions must change radically in configurations to embrace this meta-level luxury and tourism perspectives. The theoretical and practical reconfigurations include shifting from being selfish to generous, temporal to everlasting, exclusive to inclusive, hubris to humility, and linear to circular.
Impact of scaffolding and hands-on assignments within mechatronics on student learning outcomes of KEEN's entrepreneurial mindset
Authors: Vijayan Vinayak , Fang Shanpu , Barclay Skyler A , Reissman Megan E , Reissman Timothy
Published: March 2024

Scaffolding learning and incorporating hands-on activities are proven pedagogical techniques that improve student engagement. A growing movement within engineering education has been to educate beyond the technical skills and foster an improvement in students’ entrepreneurial mindset. A modified version of a validated self-efficacy tool is used here to assess the impact that scaffolding and hands-on activities within a Mechatronics course have on developing the three student learning outcomes associated with the Kern Entrepreneurial Engineering Network's entrepreneurial mindset: “curiosity,” “connections,” and “creating value” (3Cs). A total of 229 students were considered in this study. Presurveys and postsurveys were used to collect self-efficacy ratings for confidence, success, motivation, and anxiety with respect to each of the 3Cs. Additionally, for comparisons a baseline behavioral tool was assessed along with students self-reported prior experiences relevant to the course and overall time spent on course activities. The group was split into high-performers and low-performers for the purpose of analysis. For all 3Cs, aspects of student perceived confidence and success significantly increased between the presurveys and postsurveys for the entire group. However, student perceived motivation was not significantly improved for any of the 3Cs. Interestingly for “connections,” student perceived anxiety decreased only for the high-performing group. This study suggests that changes in these 3Cs can be identified within a single course when subaspects of the mindset are considered.
Semi–Bone Tunnel Technique Using Double-Row Suture Bridge Combined With Platelet-Rich Plasma Hydrogel for Rotator Cuff Repair in a Rabbit Model
Authors: Zeng Shengqiang , Sun Jiacheng , Qin Bo , Liu Yang , Liu Gang , Deng Kai , Yin Yiran , Bao Dingsu
Published: March 2024

Background:

The approach to managing the footprint area and reconstructing the tendon-bone interface (TBI) is critical for optimal healing.

Purpose:

To evaluate the outcomes of the semi–bone tunnel (SBT) technique using a double-row suture bridge combined with platelet-rich plasma (PRP) hydrogel for rotator cuff repair in a rabbit model.

Study Design:

Controlled laboratory study.

Methods:

A total of 48 New Zealand White rabbits were divided into 4 groups. The supraspinatus tendons were severed at the footprint to create a rotator cuff tear model in the surgical groups. Rabbits were treated with the traditional onto-surface repair (control group), SBT technique (SBT group), and SBT technique combined with PRP hydrogel implantation (SBT+PRP group). The rabbits without surgery were the normal group. At 8 weeks after surgery, macroscopic observation, magnetic resonance imaging (MRI) and micro–computed tomography (μCT) examinations, histological evaluations, and biomechanical tests were performed to assess the curative effects of the given treatments.

Results:

The MRI results showed that the repaired supraspinatus tendon presented a uniform signal, minimal inflammatory response, and the lowest signal-to-noise quotient value in the SBT+PRP group. The μCT results suggested that the SBT technique did not reduce the local bone mineral density in the TBI area compared with the onto-surface repair technique. The histological staining results showed that the regenerated TBI in the SBT+PRP group had a 4-layer structure similar to the natural tissue. The highest values for biomechanical properties were observed in the SBT+PRP group, and there was no significant difference between the SBT+PRP group and normal group.

Conclusion:

The SBT technique presented a better tendon-bone healing effect for rotator cuff tear in the rabbit model compared with the traditional onto-surface repair technique. The specimens in the SBT+PRP group had a similar TBI structure and biomechanical properties to the natural tissue.

Clinical Relevance:

The SBT technique can be an alternative surgical approach for rotator cuff repair, especially for moderate to large tears and cases requiring scaffold implantation.
The burden of complexity: Dealing with measurement and taxation in the Sound Toll registers – a response to Yrjö Kaukiainen
Authors: Scheltjens Werner
Published: March 2024

This paper replies to a research note outlining a method for the conversion of weights and measures in the Danish Sound Toll registers. Whereas Yrjö Kaukiainen argues that the use of values for Danish units of measurement is sufficient, Werner Scheltjens highlights the complexity of pre-modern weights and measures, and raises concerns about the simplification of the measurement and taxation procedures at the customs office in the Danish Sound.
Investigations on mechanical features and mechanical performance of rotary friction welded Al-Cu joint at optimized conditions
Authors: Murugesan Bakkiyaraj , Elaiyarasan U , Ananth Jambulingam , Nagarajan Parasumanna Krishnamurthy
Published: March 2024

In this experimental investigation, rotary friction welding (RFW) was employed to fabricate dissimilar Al-Cu joints, and the RFW variables were rotated against the ultimate tensile strength (UTS) in an effort to strengthen the dissimilar AA1100 and pure copper (Al-Cu) joint using response surface methodology (RSM) with a three-factorial design. Following this, micro-hardness, metallurgical characterization, and fatigue properties studies were done on the dissimilar joints fabricated under the optimized conditions. As a result of this investigation, the UTS of 208 MPa was attained as a maximum as the rotation speed was set at 1800 rpm, the friction time was 10 s, and the forging load was 5 kN. The dissimilar joint exhibits a better fatigue strength of 98.5 MPa when compared to the AA1100 base metal. At optimized conditions, the feature of the fracture image was found to be brittle due to the development of new compounds in the weld interface. A significant dip in micro hardness (52 Hv) was noticed in the region that connects TMAZ and HAZ of the AA1100 side of the dissimilar joint, which was concluded to be the weakest zone as the dissimilar joints were fractured in the same location during the tensile test. The observed results benefit the automotive sector, especially when fabricating components that require effective thermal management and weight reduction, like electrical connectors, heat dissipation systems, and radiators. For heat exchanger applications, improved fatigue strength in dissimilar Al-Cu joints is important because it guarantees longer structural integrity and improved durability.
An estimation of the biomechanical properties of the continent and incontinent woman bladder via inverse finite element analysis
Authors: Silva Maria Elisabete Teixeira da , Pinheiro Fábio André Teixeira , Ferreira Nuno Miguel , Brandão Fernanda Sofia Quintela da Silva , Martins Pedro Alexandre Lopes de Sousa , Parente Marco Paulo Lages , Mascarenhas Saraiva Maria Teresa da Quinta e Costa , Fernandes António Augusto , Natal Jorge Renato Manuel
Published: March 2024

Stress urinary incontinence often results from pelvic support structures’ weakening or damage. This dysfunction is related to direct injury of the pelvic organ’s muscular, ligamentous or connective tissue structures due to aging, vaginal delivery or increase of the intra-abdominal pressure, for example, defecation or due to obesity. Mechanical changes alter the soft tissues’ microstructural composition and therefore may affect their biomechanical properties. This study focuses on adapting an inverse finite element analysis to estimate the in vivo bladder’s biomechanical properties of two groups of women (continent group (G1) and incontinent group (G2)). These properties were estimated based on MRI, by comparing measurement of the bladder neck’s displacements during dynamic MRI acquired in Valsalva maneuver with the results from inverse analysis. For G2, the intra-abdominal pressure was adjusted after applying a 95% impairment to the supporting structures. The material parameters were estimated for the two groups using the Ogden hyperelastic constitutive model. Finite element analysis results showed that the bladder tissue of women with stress urinary incontinence have the highest stiffness (α1 = 0.202 MPa and µ1 = 7.720 MPa) approximately 47% higher when compared to continent women. According to the bladder neck’s supero-inferior displacement measured in the MRI, the intra-abdominal pressure values were adjusted for the G2, presenting a difference of 20% (4.0 kPa for G1 and 5.0 kPa for G2). The knowledge of the pelvic structures’ biomechanical properties, through this non-invasive methodology, can be crucial in the choice of the synthetic mesh to treat dysfunction when considering personalized options.
Industry 5.0: A comprehensive insight into the future of work, social sustainability, sustainable development, and career
Authors: Gamberini Luciano , Pluchino Patrik
Published: March 2024

Industry 5.0 marks a significant transition in the industrial sector, integrating human centricity with technological advancements. It redefines work dynamics, emphasizing social sustainability and sustainable development in shaping career paths. The necessity for equitable workforce training, prioritizing worker well-being alongside technological adaptation, is pivotal. The rapid pace of technological advancement relates to significant investment in talent development, emphasizing the workforce's upskilling and reskilling and the importance of continuous learning to meet these new challenges. It advocates for inclusive and comprehensive training programs that cater to diverse workforce needs. Addressing challenges while leveraging opportunities for social and environmental sustainability is critical for Industry 5.0's success. This transition aims to create a sustainable, inclusive industrial future where technological advancements are harmonized with human values and environmental considerations. This approach sets a new standard for industrial operations and career development, positioning Industry 5.0 as a landmark for modern, responsible, and sustainable industrial practices.
The collaborative use of career information by young people and career advisers: A thematic content analysis of career counselling records
Authors: Milosheva Marina , Robertson Peter , Cruickshank Peter , Hall Hazel
Published: March 2024

This study explores the career information-seeking behaviours of young people and career advisers. These are examined through the interrogation of a secondary data set held by Scotland's national skills agency, Skills Development Scotland. Descriptive and frequency analyses of engagement records from career conversations reveal three key characteristics of information seeking in career advisory settings: prompted information seeking; information seeking on young people's behalf and collaborative information seeking. The original contribution of this study lies in two novel research foci: (a) the identification of distinct patterns of career information-seeking behaviours and colloquial language which signifies that information seeking has taken place and (b) the consideration of young people and career advisers’ collaborative information seeking behaviours and their roles and functions within the career information-seeking process. These findings have implications for the improvement of career services and the development of career information, advice and guidance (CIAG) policies.
Exploring innovative career counselling strategies for universal relevance and sustainability in the Anthropocene era
Authors: Maree Jacobus Gideon
Published: March 2024

This article reflects on several factors that influence the art and science of career counselling in different contexts. An adapted systematic literature review was implemented to examine developments in the career counselling field and to explore innovative career counselling strategies that have universal relevance and sustainability in the Anthropocene era. The continued relevance and functionality of career counselling in South Africa (as an example of a Global South, developing country reflective of the situation globally) is examined. I reflect on a possible theoretical and conceptual framework for career counselling in the ‘career Counsellocene’ era and I argue for an approach that contextualises career counselling in different contexts in the future workplace and meets the career-counselling needs of people in the Anthropocene era. A career-counselling approach is needed that emphasises the importance of eco-awareness in reversing the impact of human abuse on the environment.
Exploring Artificial Intelligence Tool Use in a Nonprofit Workplace
Authors: Hillen Andrew
Published: March 2024

This case study offers examples of the use of artificial intelligence (AI) writing tools at a small nonprofit workplace dispute resolution center. It explores the limits and strengths of these AI tools, as well as the mediation field's concerns around using AI as a replacement for mediation work. Further, it explores the implications of AI tool use for the ethos of the writer and the AI tool itself as well as for the current pedagogy deliberations occurring in the technical writing field at large.
Preparing Future Technical Editors for an Artificial Intelligence-Enabled Workplace
Authors: Mallette Jennifer C.
Published: March 2024

How should instructors adapt technical editing courses to account for generative artificial intelligence (AI)? This article addresses what generative AI means for technical editing pedagogy. While AI tools may be able to address rote editing tasks, expert editors are still needed to provide accessible, ethical, and justice-oriented edits. After reviewing impacts of generative AI on editing praxis, the author focuses on the microcredentials that she built into an editing course in order to address these impacts pedagogically. The goal was to enable students to understand AI, argue for their expertise, and edit from ethical and social justice perspectives.
Evaluation of Psychometric Properties, Construct Validity and Measurement Invariance Across Child's Disability and Gender for the Alabama Parenting Questionnaire APQ-GR (6–18) (Parent Form)
Authors: Marinakis Georgios , Charitaki Garyfalia , Kypriotaki Maria , Markodimitraki Maria
Published: March 2024

The study's main objective was to evaluate the psychometric properties of the Greek version of the Alabama Parenting Questionnaire APQ-GR (6–18) (Parent form). A total number of n = 1118 families were enrolled in the sample. More specifically, n = 1667 parents participated in the study [mothers: ( n = 1051) and fathers: ( n = 616)]. Exploratory Factor Analysis in a sub-sample of parents ( n = 555, comprising of the entire sample) supported a 6-factor model including dimensions of parenting such as Ιnvolvement (I), Positive Parenting (PP), Poor Monitoring/Supervision (PM/S), Inconsistent Discipline (ID), Corporal Punishment (CP) and Other Discipline Practices (ODP) and explained 54.437% of total variance. CFA confirmed the proposed 6-factor model and generated satisfactory goodness of fit indices ( χ2/ df=1.73 < 2 and p = .456, TLI = .983 ≥ 0.95, RMSEA = .056 < .080, CFI = .92 ≥ .90 and SRMR = .035 < .080). No ceiling or floor effects were observed. All nested models were evaluated across the parents' gender and demonstrated a good fit for mothers and fathers. In conclusion, the Greek Alabama Parenting Questionnaire APQ-GR (6–18) (parent form) demonstrated sufficient validity and reliability evidence for assessing parenting practices.
Freedom as cultural-discursive resource
Authors: Shi-xu
Published: March 2024

Humanity has never suffered so much from racial repression, social division and cultural domination as in the contemporary world. Freedom is under the severest attack the mankind has ever seen. Erno and Birk timely seize the issue of human freedom and contend that psychologists must turn their attention to it from a practical, political and interdisciplinary perspective, thereby opening up new avenues to human flourishing and self-actualization. And yet this proposal has given still insufficient heed to the cultural nature of freedom. It is the objective of this essay to argue for and sketch out a cultural-discursive approach that purports to provide not just a systematic and precise account of freedom but also a methodological framework for its research.
Scaling Toward Utopia or Dystopia: Challenges to Preserving Organizational Values Through Growth
Authors: McCluskey Matthew S.
Published: March 2024

In their nascent stages, charter schools formed under competing ideologies. In academic circles, charter schools were envisioned as pedagogical laboratories that would allow for educator- and community-driven school improvement. In other circles, charter schools emerged as a free-market reform driven by accountability, choice, and growth. Amid the neoliberal accountability era, the latter ideology has emerged as a stronger driving force across the educational landscape, particularly amid the proliferation of Charter Management Organizations (CMOs). Based on real events, a charter school founder struggles to hold onto organizational values while scaling from a small charter school to a large CMO.
Modified upside-down technique with Gore tapered iliac limbs for isolated iliac artery aneurysms
Authors: Pennetta Federico Francisco , De Santis Francesco , Millarelli Massimiliano , Diotallevi Nicolò , Chiappa Roberto
Published: March 2024

Purpose

To describe the off-label use of tapered iliac limbs for the treatment of isolated iliac aneurysms with proximal landing zone significantly larger than distal landing zone.

Technique

Inversion of a Gore Excluder tapered leg (W. L. Gore & Associates Inc, Flagstaff, Arizona) with a modified upside-down technique is described. The endoprosthesis, with the olive at the tip of the releasing system previously cut, is inserted in a tip-to-tip fashion into a 15 Fr introducer sheath. The graft is released inside the introducer. An 18 Fr introducer sheath is advanced up to the proximal sealing zone. Following the removal of the 18 Fr dilator, the 15 Fr introducer with the pre-released graft is inserted co-axially into the 18 Fr introducer. A pre-cut 15 Fr dilator is brought up to the endograft and used as a pusher. A pull-back maneuver of the co-axial system, countertractioning with the dilator maintained in position, allows the delivery of the endograft.

Conclusion

This technique might offer a feasible option in case of endovascular exclusion of isolated iliac artery aneurysms with significant landing zone diameter mismatch. Extracorporeal inversion is time-saving and could be safer in terms of graft damage and infection.
From biology to clinical practice: antiproliferative effects of somatostatin analogs in neuroendocrine neoplasms
Authors: Melhorn Philipp , Mazal Peter , Wolff Ladislaia , Kretschmer-Chott Elisabeth , Raderer Markus , Kiesewetter Barbara
Published: March 2024

Somatostatin analogs (SSA), specifically octreotide and lanreotide, have demonstrated antiproliferative effects in patients with neuroendocrine tumors (NET), a group of rare malignancies of diverse origin and presentation. A prominent feature of NET cells is the expression of G protein-coupled receptors called somatostatin receptors (SSTR). Although these SSTR are not uniformly present in NET, they can be instrumental in the diagnosis and treatment of NET. Apart from their application in nuclear imaging and radionuclide therapy, SSA have proven invaluable in the treatment of hormonal syndromes associated with certain NET (antisecretory effects of SSA), but it took more than two decades to convincingly demonstrate the antiproliferative effects of SSA in metastatic NET with the two pivotal studies PROMID and CLARINET. The current review summarizes three decades of SSA treatment and provides an overview of the clinical trial landscape for SSA monotherapy and combination therapy, including clinical implications and quality of life aspects, as well as ongoing fields of research.
Patient-reported outcomes in integrated health and social care: A scoping review
Authors: Hughes Sarah E , Aiyegbusi Olalekan L , McMullan Christel , Turner Grace M , Anderson Nicola , Cruz Rivera Samantha , Collis Philip , Glasby Jon , Lasserson Daniel , Calvert Melanie
Published: March 2024

Patient-reported outcomes (PROs) have potential to support integrated health and social care research and practice; however, evidence of their utilisation has not been synthesised.

To identify PRO measures utilised in integrated care and adult social care research and practice and to chart the evidence of implementation factors influencing their uptake.

Scoping review of peer-reviewed literature.

Six databases (01 January 2010 to 19 May 2023).

Articles reporting PRO use with adults (18+ years) in integrated care or social care settings.

We screened articles against pre-specified eligibility criteria; 36 studies (23%) were extracted in duplicate for verification. We summarised the data using thematic analysis and descriptive statistics.

We identified 159 articles reporting on 216 PRO measures deployed in a social care or integrated care setting. Most articles used PRO measures as research tools. Eight (5.0%) articles used PRO measures as an intervention. Articles focused on community-dwelling participants (35.8%) or long-term care home residents (23.9%), with three articles (1.9%) focussing on integrated care settings. Stakeholders viewed PROs as feasible and acceptable, with benefits for care planning, health and wellbeing monitoring as well as quality assurance. Patient-reported outcome measure selection, administration and PRO data management were perceived implementation barriers.

This scoping review showed increasing utilisation of PROs in adult social care and integrated care. Further research is needed to optimise PROs for care planning, design effective training resources and develop policies and service delivery models that prioritise secure, ethical management of PRO data.
Remediation of Per- and Polyfluoroalkyl Substances in Nonwoven Production and Paper Sectors: A Brief Review
Authors: Newland Ashley , Halamek Jan , Ramkumar Seshadri
Published: March 2024

Per- and polyfluoroalkyl substances are a growing concern in the paper and nonwoven industry, as current research provides alarming results regarding the abundance and persistence of these substances from food packaging producers. It was reported that per- and polyfluoroalkyl substances have been detected in blood serum of thousands of individuals originating from food packaging that contains per- and polyfluoroalkyl substances. In addition, 20–56% of all products tested had detectable levels that immensely contribute to dietary exposure. Paper mills are also a significant source of exposure due to environmental contamination surpassing emission regulations set by the Environmental Protection Agency by over 100,000 parts per trillion. These studies exemplify the necessity for paper-based product producers to not only abide by regulations but also demonstrate the implementation of remediation efforts. With current research on novel remediation techniques and increased restrictions surrounding per- and polyfluoroalkyl substance usage for water repellency, decreased contamination and exposure will be achieved throughout the world. This article serves as a brief review that focuses on the nonwoven manufacturing sector, which includes pulp, paper, and tissue related to per- and polyfluoroalkyl substance contamination in the environment and drinking water sources. This review addresses the statistical evaluation of per- and polyfluoroalkyl substance levels throughout the world from paper and nonwoven product manufacturing, along with remediation methods and legislation to reduce contamination and exposure. To the best of our ability, this important and sensitive subject area has been researched extensively. However, many data gaps are present within the field, and limited studies have been conducted contributing to this brief review, which highlights the importance of further studies surrounding per- and polyfluoroalkyl substances in the paper and nonwoven sectors. This article encompasses all available information in the paper and nonwoven sector regarding per- and polyfluoroalkyl substances that can be used for reference by the general public and by manufacturers in the nonwoven production industry.
Evidence Guiding Commercial Payer Coverage Criteria for Total Ankle Arthroplasty
Authors: Kotlier Jacob L. , Fathi Amir , Ong Meng-Yung , Yazditabar Josh M. , Panoussi Ethan E. , Mayfield Cory K. , Petrigliano Frank A. , Liu Joseph N. , Peterson Alexander B. , Tan Eric W.
Published: March 2024

Background:

Total ankle arthroplasty (TAA), first developed as an alternative to ankle arthrodesis, has become an increasingly popular management option for end-stage ankle arthritis. Prior studies have shown commercial insurance payers base their coverage criteria on limited and low level of evidence research. This study aims to quantify and describe the evidence insurance companies use to support TAA coverage policies.

Methods:

The top 11 national commercial health insurance payers for TAA were identified. A google search was performed to identify payer coverage policies. Policy documents were examined and cited references were classified by type of reference as well as reviewed for level of evidence (LOE). Specific coverage criteria for each individual payer were then extracted. Criteria were compared to assess for similarities among commercial payers. Finally, all references cited by each payer were examined to determine whether they mentioned the specific payer criteria.

Results:

Six of the 11 payers had accessible coverage policies. The majority of cited references were primary journal articles (145, 60.9%) and the majority of references cited (179, 75.2%) were level III or level IV evidence. We found significant homogeneity in coverage criteria among payers. In addition, cited sources inconsistently mentioned specific payer coverage criteria.

Conclusion:

This study demonstrates that commercial insurance payers rely on the relatively low level of currently available scientific evidence when formulating coverage policies for TAA use and adopt criteria that have not been thoroughly analyzed in the literature. More high level of evidence research is needed to help clinicians and insurance companies further refine indications for TAA so that patients who might benefit from the procedure are adequately covered.

Level of Evidence:

Level IV, review.