bluuebunny/crossref_metadata_2025 huggingface dataset:
Simultaneous Quantification of Mometasone Furoate and Formoterol Fumarate in Bulk and Formulations by RP-HPLC Method
Authors: B Sivagami , M Bhaskar , Kumar V Pavan , D Meena , Kumar G Satheesh , R Chandrasekar
Published: January 2024

A simple and robust reversed-phase high pressure liquid chromatographic method was developed and validated for the quantification of Mometasone and Formoterol in bulk and fixed dosage forms. The column utilized for study was Inertsil C18, ODS was chosen for good peak shape. Ambient temperature was found to be suitable for the nature of drug solution. The mobile phase was streamlined with a ratio of 35:65 Methanol: Water was optimized for symmetrical peaks and good resolution. The flow rate was streamlined at 1.0 ml/min because of good peak area, satisfactory retention time and good resolution. Common λ-max was found to be at 278 nm and Injection volume was 20 µl which gave a good peak area. The percentage recovery was found to be 98.0-101.50 was linear and precise over the same range. Both system and method precision was found to be accurate and well within the acceptable limits. Detection limit was found to be 0.25 Mometasone and 0.34 for Formoterol. The analytical method was found linearity over the range of 20-80 ppm of the target concentration for both the drugs. The LOD and LOQ values for Mometasone, was observed to be 0.25 and 0.77 and for Formoterol was in the range of 0.34 and 1.05 consecutively. The analytical method passed both intermediate precision and robustness tests. On both cases, relative standard deviation was well satisfactory. The validation experiments met ICH standards. It inferred the method found to be simple, accurate, precise and linear. The method was found to be having suitable application in routine laboratory analysis with high degree of accuracy and precision.
Nitrosamine Impurity: Management of Unwelcome Guest in Pharma Market
Authors: I. Patel Ajay , K. Mandavia Anjali , J. Vyas Amit , B. Patel Ashok
Published: January 2024

Nitrosamine impurities have been detected in various pharmaceutical products in recent days. Various sartans, ranitidine, nizatidine and metformin have been recalled from the markets due to the high limit of nitrosamine impurities. When assessing the danger of human cancer, pharmaceutical products ability to regulate potentially mutagenic and carcinogenic contaminants is crucial. The risk of their mutagenic and carcinogenic potential has increased with the recent finding of nitrosamine impurities in various commercially available medications. Nitrosamine is the substance deemed to be a potential human carcinogen by the International Agency for Research on Cancer (IARC). Impurities in nitrosamines have been shown to be mutagenic and carcinogenic; even very low exposure levels to these impurities can cause cancer. These impurities may be created by a reagent, catalyst, solvent, or raw materials employed in the manufacturing process and end up in drug substances or drug products. Angiotensin II receptor blocker (ARB) medications with nitrosamine impurities have caused widespread health problems. Risk management of nitrosamine impurity is necessary to control the level of this impurity in drug substance, drug product and APIs. By using risk management tools like fishbone diagram which is used to identify and organize the possible sources of nitrosamines in medicines. For detection of nitrosamine impurity different countries develops their own analytical methods.
Gel Chromatography: A Review Short
Authors: Pandurang Wagh Chetana , Suresh Sharma Shruti , Chaudhari Dhananjay
Published: January 2024

Gel filtration chromatography is a popular and versatile technique that provides high efficiency separation of proteins and biomolecules. Here, the basis of the method is explained and compared with the matrix type. The selection of appropriate study and application methods is also discussed
Evaluation of antidepressant activity of Polyherbal methanolic extract of leaves of Zingiber officinale, Azadirachta indica, Curcuma longa and Hibiscus rosasinesis
Authors: Gopal Makwana , Sachin Kumar Jain , Sudha Vengrelekar
Published: January 2024

Aim: The Present studies were evaluate antianxiety activity of methanolic composite leaves extract of (Zingiber officinale, Azadirachta indica, Curcuma longa and Hibiscus rosasinesis) on administration in rats. Method: Male albino Wistar rat were taken and divided into 5 groups and each group contain 4 rats. Diazepam (1mg/kg) and composite extract (50mg/kg, 75mg/kg and 150mg/kg) were suspended in water and administrate orally. In these studies vehicle/ drugs were given 30min before exposure to experimental model such as actophometer and rotarod. C.E increase locometry actvity and time taken by rat to falling from the rod in actophometer and rotarod. The activity of rat is compared with standard drugs diazepam (1mg/kg). Result: The studied shown that at dose of 50mg/kg, 75mg/kg and 150mg/kg composite extract posse’s significant antidepressant activity.
Isolation, Characterisation and Evaluation of Plastic Degrading Properties of Soil Biofilms Collected from Chennai District
Authors: S R Vijayakrishnan , Parvathi V Deepa , Sumitha R
Published: January 2024

Environmental pollution due to accumulation of synthetic polymers namely plastics is a growing concern which threatens the terrestrial marine flora and fauna. Traditional methods of plastic disposal include incineration and disposal into landfills or water bodies. Incineration of polyethylene, polystyrene leads to emission of a large amount of carbon monoxide which is toxic if inhaled and also a potent greenhouse gas. Degradation of plastic by microorganisms is an efficient and eco-friendly method employed for rapid rate of disintegration. The biofilm present in the contaminated soil survives by adapting to harsh environment by secreting hydrolysing enzymes which are potent in degradation of the accumulated plastics. The present study deals with the isolation, characterisation and evaluation of plastic degrading properties of microorganisms isolated from various soil samples collected from Chennai district. Soil samples were collected aseptically from various locations & isolated by standard plate count method. The isolated organisms were identified by staining methods and characterized by phylogenetic analysis. The organism Pseudomonas aeruginosa and Streptomyces fulvissimus were further subjected to plastic degradation testing. The present study demonstrates the ability of Pseudomonas aeruginosa and Streptomyces fulvissimus to degrade polyethylene sheets.
Microwave Generated Nanocomposites for Solubility Enhancement
Authors: Rohom Ashitosh , Mankar S.D.
Published: January 2024

Nanocomposites is technique used for solubility enhancement. Macro particle are breaking down in micro Nano particle by different technique. Nanocomposites, a high performance material exhibit unusual property combinations and unique design possibilities. With an estimated annual growth rate of about 25% and fastest demand to be in engineering plastics and elastomers, their potential is so striking that they are useful in several areas ranging from packaging to biomedical applications. In this review article we will discuss about solubility enhancement technique like nanocomposite. We will overview about nanocomposite, type of Nanocomposites, method of preparation, advantages, disadvantages, application of nanocomposites.
A Review: The Current Scenario for Tomato Flu
Authors: Sharma Isha , Sharma Neha , Moda Michi , Thakur Mansi , Sharma Kriti
Published: January 2024

The unidentified virus that causes tomato flu is an infectious disease.Tomato-shaped ulcers that appear all over the body and develop into tomatoes in appearance are the infection's disease virus, hence the name "Tomato flu" or "Tomato fever.It primarily affects young children under five.. A "Hand, Foot, and Mouth disease" is tomato flu. HFMD is caused by viruses that belongs enterovirus genus. Coxsackie virus A16is most frequent cause of HFMD. Although there is a low chance that this illness will produce meningitis. Tomato flu is originally discovered in Kerala. Tamil Nadu, Orissa, and the rest of India have not yet seen the effects of the virus outside of Kerala.The majority of clinical manifestations cases are minor. The infection is self-limiting and will go away on its own in 7–10 days.In areas where there are outbreaks, On the basis of the physical examination and clinical history, the diagnosis is made. It typically breaks out in epidemics throughout the spring, summer, and winter. The etiological agent of this infectious disease, its course of therapy, and vaccine are still unknown, and this is an important topic of research right now. The most efficient and affordable methods of preventing viral infections in the general population.There are currently non-antiviral drugs and vaccinations available for the treatment and prevention of tomato flu.COVID-19 has provided valuable lessons for prepare for outbreaks and manage cases under emergency circumstances by repurposing medications and vaccines, which is another way to say that efforts are now being made to control the condition.
Development of a Kinetics Based Onsite Treatment System for Faecal Sludge Treatment and Resource Recovery
Authors: Sakhre Saurabh , Ajantha S , Bisarya Abhishek , Vijay Ritesh , Bhaskaran Krishnakumar
Published: January 2024

The management of faecal sludge in cities without a sewerage system is a challenging problem that requires immediate attention. The high organic and nutrient content, pathogen load, and pharmaceutical residues in faecal sludge necessitate special attention for its treatment to ensure
environmental and public health safety. Onsite treatment of faecal sludge with a focus on resource recovery is a sustainable approach to its management. However, studies in these areas are limited, particularly in the Indian context. In this study, the aim is to generate primary data on the
current status of faecal sludge management in a model region without a sewerage network. Additionally, kinetic parameters were examined to design an anaerobic bioprocess and an engineered system for resource-oriented faecal sludge treatment. One of the wards in Thiruvananthapuram Corporation,
Kerala was selected for the study. Fresh faecal sludge collected from an apartment complex was used for the experimental studies. Anaerobic treatment of fresh faecal sludge was validated in bench-scale experimental bioreactors using different combinations: with mixing without inoculum, with
mixing with inoculum, without mixing without inoculum, and without mixing with inoculum. The primary focus was on monitoring the organic removal efficiency as Chemical Oxygen Demand (COD) of these combinations. Among the four combinations tested the units "without mixing with inoculum"
and "with mixing with inoculum" demonstrated COD removal efficiencies of 20.89% and 18.91%, respectively, with a first-order rate constant of 0.0008 hr-1 for both combinations. The other combinations exhibited comparatively lower COD removal efficiency and rate constants. Since the
combinations with mixing and inoculum showed higher COD removal efficiency, either of them can be adopted for design purposes. Based on these results, a combined anaerobic-aerobic treatment unit is proposed for the treatment of faecal sludge.
Analysis and Proposal for Actors' Roles in Solid Waste Management in the City of Fortaleza (Brazil)
Authors: Júnior Nilo Alves , Pinto Francisco Roberto , Câmara Samuel Façanha
Published: January 2024

The continuous population growth and the high rate of urbanization of cities, added to the growing consumption of products, result in the proportional generation of solid waste that brings various harms, such as air and water pollution, soil contamination and degradation, proliferation
of various diseases and devaluation of urban real estate. In Fortaleza, regardless of its size or number of inhabitants, waste is collected through the action of collectors belonging to the most miserable layers of the population, without adequate preparation to carry out such activity and
by a mega private company hired by the City Hall, with serious doubts about the execution of your work. This article analyzes the roles of public and private actors involved in the solid waste management process in the city of Fortaleza, Brazil, and suggests a new configuration for this operation
that takes into account the needs of the community and more effective and necessary actions such as collection selection, review of waste disposal, use of gas and fertilizer generated in sanitary landfills, and greater attention to the work of collectors. Fortaleza is a capital that generates
millions of tons of solid waste per year, with an obvious difficulty in dealing with this, caused by the inefficiency in solving the associated problems. We used a qualitative methodology for exploratory research, based on interviews with public and private managers related to solid waste
management. We analysed the interviews through Content Analysis, using the Iramuteq software, and unveiled the roles of the different actors.
Impact of Wastewater from Outfall of River on Bitter Gourd: Morphological and Biochemical Studies, Peptide Synthesis and Antioxidant Activity
Authors: Kar Sayanti , Ghosh Indrajit , Ghosh Amitava , Aitch Pritam , Bhandari Gupinath
Published: January 2024

River pollution poses a significant concern for the people of India who heavily rely on river water for daily needs. This study focuses on assessing the status of river pollution in West Bengal, India, with a particular emphasis on a major canal (N22° 39'08.75'' E88°
21'27.60'') near Dakhineswar New Jetty, known for its Kali Temple and frequent ritual activities. The region's dependence on river water is evident in daily life. Analysis of three consecutive years (2016-2018) reveals alarming levels of Total Coliform, reaching up to 8.18 x 106 MPN/100ml
during the premonsoon season. Disturbingly high concentrations of Lead (0.069 mg/L) and Mercury (0.008 mg/L) are recorded. Average Dissolved Oxygen (DO) and Biochemical Oxygen Demand (BOD) are 2.3 mg/L and 7.9 mg/L, respectively, during the premonsoon. The impact of wastewater on Bitter Gourd
(Momordica charantia L.) manifests in detrimental changes to both morphological and biochemical parameters, including total chlorophyll and protein content. Low molecular weight peptide(s) (3.0-0.5 kDa) are extracted, purified, and analyzed through ion exchange resin column, ultra-filtration,
and HPLC. HPLC analysis distinguishes the presence of peptides compared to the control, revealing adverse effects of wastewater. The antioxidant activity of low molecular weight peptide(s) is demonstrated through DPPH scavenging. Bioassays, such as the germination percentage of wastewater-treated
Bitter Gourd seeds, indicate inhibition. The intensified impact of wastewater during the premonsoon season underscores the urgency of addressing river pollution in this region.
Review of the Existing Organic Waste Management Situation in Kerala
Authors: Ekanthalu Vicky Shettigondahalli , Narra Satyanarayana , Jalalipour Haniyeh , Antwi Edward , Singh Vidhi , Narra Mona Maria , Nelles Michael
Published: January 2024

In India, the rapid economic development has resulted in a change in the lifestyle of urban dwellers, which has changed the composition of the waste generated. Due to the high volume of waste generated, the collection, transportation, and disposal stream requires a highly efficient
system. It requires knowledge of what the wastes are comprised of, how they need to be collected and disposed of, and the participation of citizens, local governments, and private entrepreneurs. With the vision to transform Kerala into a garbagefree state and achieve full-scale environmental
health, Kerala has notified the principle of 3Rs in the State Policy on Solid Waste Management. As per Suchitwa Mission annual report 2019-2020, in the year 2019-2020 Kerala has generated 10,044 TPD of Municipal Solid Waste. With a population growth rate of approximately 10.24%, Kerala could
generate 16,565 TPD of waste in 2036. This increase in waste generation could put substantial pressure on the existing waste management system of Kerala. Thus, there is a greater need to investigate alternative waste management options and expand the capacity of the waste management system
in Kerala. Landfills have also been widely unsuccessful in the state of Kerala. According to the Suchitwa mission' s latest data, Kerala has 51 notified dumpsites of which only 31 are in operation and 14 dumpsites have a volume≤ 800 m3. Additionally few dumpsites are very close to human
settlements and located close to each other. In the current article a detailed review of the waste generation, composition, organic waste treatment and disposal methods are made, and gaps in the present waste management practice are outlined. The identified gaps are examined to fulfill the
defined requirements in the solid waste management law of the respective state and the comprehensive rules laid down by the Government of India (Gol) in its Solid Waste Management Rules 2016.
IDENTIFIKASI KOMPETENSI SUPERVISI KEPALA SEKOLAH DI TK KECAMATAN ADIPALA
Authors: Lathifah Inayatul , Baroah Siti
Published: January 2024

Supervisi akademik adalah bantuan professional yang diberikan kepada guru melalui siklus perencanaan sistematis, pengamatan yang cermat, serta umpan balik yang objektif dan segera oleh supervisor. Tujuan dari penelitian ini adalah mengetahui dan mengidentifikasi supervisi akademik yang dilakukan oleh kepala sekolah terhadap guru di TK Kecamatan Adipala. Jenis penelitian ini yaitu deskriptif kuantitatif, dengan subjek penelitian kepala Sekolah TK di Kecamatan Adipala. Teknik pengumpulan data berupa angket, yang dianalisis menggunakan analisis deskriptif kuantitatif dari hasil pengisian angket tersebut, kemudian diolah dan disimpulkan dalam bentuk deskriptif. Temuan dari penelitian ini dapat diidentifikasi supervisi akademik kepala sekolah TK terhadap guru di Kecamatan Adipala pada empat komponen. Pertama, dalam menyusun perencanaan supervisi akademik 86,7% kepala sekolah sudah membuat jadwal supervisi dan rentang pelaksanaannya 40% menyebut dua kali dalam setahun, dan sisanya menyebut satu, tiga, dan empat kali dalam setahun, dan 93,3% sudah menyiapkan instrument. Kedua, melaksanakan supervisi akademik, seluruh kepala sekolah sudah melakukan pengamatan, namun baru 86,7% melakukan wawancara dan 93,3% membuat catatan hasilnya. Ketiga, menyusun laporan hasil supervisi akademik, 86,7% kepala sekolah yang menganalisis dan 93,3% membuat laporan hasil supervisi akademik. Keempat, Menentukan tindak lanjut hasil supervisi akademik terhadap guru, berupa pemberian penguatan dengan pujian, motivasi, isyarat, dan hadiah, serta pembinaan melalui nasihat, diskusi, rapat, dan fasilitasi administrasi KBM.
STUDI AL-QUR’AN TENTANG PERINTAH SHALAT DALAM SURAT LUQMAN AYAT 17
Authors: Dafiniyatul Azizah
Published: January 2024

Pengabaian orang tua terhadap anak terjadi dimana-mana, sehingga banyak anak-anak yang melakukan pelanggaran terhadap norma agama, norma sosial, norma adat dan lain-lainya. Kesibukan orang tua dalam dunia kerja menyebakban anaknya tidak terawat dengan baik dan tidak diperhatikan masalah pendidikannya terlebih dalam perintah sholat. Akhir-akhir ini semakin banyak orangtua yang fokus duniawi saja dan mengesampingkan urusan akhirat. Metode penelitian ini menggunakan studi pustaka (library research) yaitu metode dengan pengumpulan data dengan cara memahami dan mempelajari teori-teori dari berbagai literatur yang berhubungan dengan tafsir surat Luqman ayat 17. Surah Luqman ayat 17 memuat perintah kepada anak untuk mendirikan shalat, karena shalat merupakan rukun islam dan memiliki manfaat yang sangat. Ayat tersebut juga menggambarkan pendidikan yang diberikan oleh Luqman kepada anaknya, sebagai contoh bagi orang tua dalam mendidik anak. Perintah shalat dalam ayat ini mencakup melaksanakan shalat dengan baik, tunduk kepada Allah, dan menghasilkan kesadaran ruhani untuk mencegah perbuatan buruk. Kekhusyukan dalam shalat adalah hal yang penting, sehingga shalat tidak hanya menjadi rutinitas tanpa dampak dan tidak dapat mempengaruhi orang lain secara positif. Dalam konteks pendidikan, mengajak dan membimbing anak dalam beribadah, seperti shalat berjamaah, dapat dimulai dari dalam keluarga. Pentingnya pendidikan tentang shalat dalam keluarga, melaksanakan dengan baik, dan memiliki kesadaran ruhani untuk mencegah perbuatan buruk dan menghadapi ujian dengan kesabaran.
Evaluating Adropine levels in kidney tissue after Methotrexate treatment in rats: a prospective experimental study
Authors: Ahmet Karakeci , Tuncay Kuloglu , Can Acisu Tutku , Ahmet Keles , Tunc Ozan , Osman Vural , Irfan Orhan , Emel Sabaz Karakeci
Published: January 2024

In this study, it was aimed to investigate Adropin levels in kidney tissues after Methotrexate (MTX) administration to identify potential changes following administration of agents with antioxidant/anti–inflammatory potential. Twenty four adult rats male albino Wistar rats were used in this study, and randomly divided into four groups. Control: These rats did not receive any treatment during the 14–day (d) experiment. N–acetylcysteine (NAC): These rats were administered 100 mg·kg-1·day-1 NAC intraperitoneally (i.p.) for 14 d. MTX: A single dose of 20 mg·kg-1 MTX was administered i.p. at the beginning of the study. MTX+ NAC: A single dose of 20 mg·kg-1 MTX was administered i.p. at the beginning of the study, and the rats were given 100 mg·kg-1·day-1 NAC i.p. for 14 d. Total antioxidant, and serum Adropin levels were found to be the lowest in the MTX group while the oxidant levels were significantly lower in the MTX group than in the MTX+NAC group (P<0.001). TUNEL positivity was similar among the groups, and no significant differences were observed. It was considered that these findings have shed light on the role of Adropin in the development of kidney failure following MTX administration.
Peran kendal sebagai kawasan ekonomi khusus dalam transformasi ekonomi: analisis strategis dan implementasi melalui matriks SWOT
Authors: Sarfiah Sudati Nur , Septiani Yustirania , Sugiharti Rr. Retno
Published: January 2024

Since being designated as a Special Economic Zone (KEK), Kendal is expected to be able to become the axis of the economy on the island of Java. The establishment of KEK especially KEK Kendal is expected to stimulate investment and business growth which will have an impact on increasing employment and reducing poverty. Nationally, the purpose of creating KEK is economic equity, especially in terms of income and the competitiveness of national products. The establishment of a special economic zone requires careful preparation and commitment from all interested parties to support the implementation of the area's activities. The preparations include policies and institutions, incentives and financing, as well as infrastructure completeness according to the spatial plan. While special economic zones can offer many benefits, on the other hand many special economic zones have been criticized for their high social and economic costs. The purpose of this research is to formulate an appropriate strategy for the development of the Kendal area as a special economic zone. The SWOT matrix that has been formed has described how the strategy can be carried out in the future.
Robotic ureteroureterostomy for correction of a retrocaval ureter
Authors: Sarfo Frank , Limback Kylie , Sarver Jordan , G Anderson Barrett
Published: January 2024

Introduction: Retrocaval ureter is a rare condition identified in the adult patient usually revealing dilation of the proximal ureter as it passes posterior to the inferior vena cava. The presentation can vary from incidental radiographic findings to declining renal function secondary to hydronephrosis. Management of a retrocaval ureter typically involves surgery in patients who have symptoms or deterioration in renal function.

Case Report: This case report explores the diagnosis and treatment of a retrocaval ureter in a 34-year-old male who was referred to Urology after the detection of right-sided hydronephrosis on computed tomography (CT). Further management included a confirmatory CT, diuretic renogram, and retrograde pyelogram before definitive treatment with robotic ureteroureterostomy.

Conclusion: This case report explores the surgical steps to a robotic-assisted ureteroureterostomy to treat a retrocaval ureter that resulted in significant hydronephrosis and flank pain.
Keberkesanan Pembelajaran Teradun Melalui Penggunaan Aplikasi Web 2.0
Authors: Mokhlis Safiek
Published: January 2024

In line with the rapid development of information and communication technology (ICT), the Ministry of Education Malaysia emphasized the use of technology in teaching and learning activities to make learning experiences more meaningful to students. Institutions of higher learning are encouraged to implement blended learning that can be supported by the use of Web 2.0 applications. The purpose of this study is to explore the effectiveness of blended learning through Web 2.0 applications in a public university. The study utilized qualitative data collection techniques such as interviews and focus group discussions. Subjects of the study consisted of two lecturers and six undergraduate students. The study have identified the steps in applying Web 2.0 in blended learning including preparation, recognizing students’ basic knowledge and experience, identifying the level of interactivity, using appropriate assessment strategies, and reflection. Blended learning with the use of Web 2.0 application is effective in increasing the interaction between lecturers and students, increasing student engagement, enhancing student understanding of a topic, creating a fun learning environment, contributing to self-learning, changing students’ attitude and improving their skills in using ICT. Pedagogy, lecturers, students and infrastructure are the four key aspects that determine the sustainability of Web 2.0 applications in blended learning.
Sodium-glucose Cotransporter 2 Inhibitors in Kidney Transplant Recipients – A Retrospective Single Center Study
Authors: Freitas Joana , Francisco José Teixera , Trigo Miguel , Carvalho Renata , Vilela Sara , Silvano José Luís , Ribeiro Catarina , Malheiro Jorge , Pedroso Sofia , Almeida Manuela , Fonseca Isabel , Martins La Salete
Published: January 2024

Introduction: Considering the rising occurrence of posttranplant diabetes and the elevated cardiovascular burden among transplant recipients, the utilization of SGLT2 inhibitors (SGLT2i) in this group is appealing because of their cardiovascular and renoprotective benefits. Nevertheless, there is a scarcity of evidence for diabetic kidney transplant recipients (DKTRs) owing to concerns about potential renal graft damage and adverse effects. Methods: This retrospective study was devised to assess the effectiveness and safety of SGLT2i in kidney transplant recipients (KTRs). The main focus was on evaluating their impact on parameters such as haemoglobin A1c levels, body mass index (BMI), lipid panel, haemoglobin levels, renal allograft function (estimated glomerular filtration rate) and urirnary protein-to-creatinine ratio. Results: A total of 75 renal transplant patients were included in this investigation. The study spanned a median observation period of 18 (2.0–71.0) months. Median estimated glomerular filtration rate at baseline was 61,9 (26–120) mL/min/1.73 m2 and remained stable throughout the follow-up. Median HbA1c decreased from 7.5 to 7.0% (95% CI; p<0,002). A significant improvement in BMI (95% CI; p<0,001) and lipid panel (95% CI; p<0,05) were also observed. Median haemoglobin rate at baseline was 13,5g/dL and modestly improved at end of follow-up to 13,7g/dL (p=0,12). Regarding urinary protein:creatinine ratio, levels slightly but not significantly rose [+0.05 g/g (p=0,9)]. In a post-hoc subgroup analysis, the rate of urinary tract infections was low (10%). No other side effects were observed during the treatment course. Conclusions:This study demonstrates that the administration of SGLT2i is viable and well-tolerated, with no notable side effects observed in KTRs. However, the question of whether SGLT2i can effectively lower cardiovascular mortality and enhance allograft survival in these patients remains to be explored in subsequent studies.
Creation of a system for designing textile patterns using an iterative function system
Authors: Zhang Chunxia
Published: January 2024

This study conducted research to tackle the issues of inadequate pattern design impacts and pattern distortion in textile pattern design systems. Using the experimental verification method, the iterative function system is tried to be used in the textile pattern design system. Through the iterative function system, the system hardware structure configuration can be improved, the system software function can be optimized, the system operation efficiency can be improved, and the pattern design and textile clarity and accuracy can be guaranteed. The textile pattern design system based on an iterated function system has high practicability in the practical application process, which can better prove the system's efficiency and improve the accuracy of pattern simulation. The fractal pattern created based on fractal theory perfectly combines science and art. These patterns can greatly enrich the pattern types of textiles and shorten the pattern design cycle. At the same time, it also breaks the habitual thinking of the human brain to a certain extent, broadens the thinking and vision for designers, helps designers develop new creative resources, and takes it as the entry point of pattern design in the textile industry, bringing new vitality to textile art design. This paper provides rich experience and guidance for textile pattern design systems based on iterated function systems and enriches the existing literature.
Dampak Minat Baca Terhadap Hasil Belajar Bahasa Indonesia Bagi Siswa SDIT Insan Mulia Karangkobar
Authors: Ramadhani Dita Mulyana , Hafizh Muhamad Raihan
Published: January 2024

belajar siswa kelas tiga di SD IT Insan Mulia Karangkobar. Metode yang digunakan pada penelitian ini yaitu survei dengan pendekatan kuantitatif. Populasi yang digunakan ialah semua siswa kelas tiga dengan jumlah total 25 siswa. Hasil data dikumpulkan menggunakan angket dengan skala yaitu Likert. Analisis data dilakukan dengan teknik regresi sederhana. Penelitian menunjukkan hasil bahwa terdapat kecenderungan efek yang positif antara minat baca siswa terhadap hasil belajar siswa kelas tiga di SD IT Insan Mulia Karangkobar khususnya dalam mata pelajaran Bahasa indonesia. Data yang sudah diolah kemudian menunjukkan hasil yaitu minat baca siswa dengan tingkat status sedang berada pada persentase 44%, kemudian untuk minat baca siswa dengan tingkat status baik berada pada persentase 64%. Berdasarkan kesimpulan data penelitian yang telah didapat dan dikaji, menunjukkan minat baca mempunyai efek atau kecenderungan positif terhadap hasil belajar siswa, terutama dalam konteks ini yaitu mata pelajaran Bahasa Indonesia. Kesimpulan ini diperoleh melalui pengkajian data hasil belajar siswa kelas tiga di SD IT Insan Mulia Karangkobar khususnya untuk mata pelajaran Bahasa Indonesia yang dibuat dalam bentuk persentase
Pembelajaran Multiliterasi dalam Film Teater “I La Galigo”
Authors: Zulham Muhammad , Herdiana Besse , Madeamin Sehe
Published: January 2024

Pembelajaran multiliterasi akhir-akhir ini menjadi sangat menarik karena dengan mempelajari dua atau lebih materi literasi kita dapat melihat bagaimana keterkaitannya dengan materi literasi lainnya. Apalagi dalam pembelajaran sastra dan bahasa, film I La Galigo di tanah Bugis Makassar merupakan film teatrikal yang diakomodir dan dipertunjukkan khusus untuk masyarakat Bugis Makassar di Sulawesi Selatan. Film ini biasanya hanya dibuat untuk mengenang I La Galigo. Namun dalam penelitian ini film akan dikaji sehingga dapat menghasilkan penilaian multiliterat yang terkandung dalam film tersebut. Hasil penelitian ini menunjukkan bahwa pembelajaran multiliterasi secara tuntas dapat dipelajari bahkan dalam film drama atau konteks budaya tertentu Dengan memperhatikan beberapa aspek yaitu sumber informasi tentang I La Galigo, proses peralihan karya tulis ke dalam naskah pertunjukan teater dan juga respon dunia internasional. Pengalihan karya tulis I La Galigo menjadi sebuah naskah pertunjukan teater sangat memperhatikan detail yang diperoleh dari kelompok budaya dan juga Bissu di Sulawesi Selatan. Tidak hanya sebatas dialog, keseluruhan sistem unsur dalam panggung teater tidak menghilangkan nilai-nilai dan gagasan I La Galigo itu sendiri.
Strategi Penerjemah sebagai Mediator Budaya dalam Menerjemahkan Novel Indonesia ke Bahasa Inggris
Authors: Syamsinar Syamsinar , Hasby Muhammad , Hermini Hermini
Published: January 2024

Artikel ini membahas kajian tentang strategi penerjemah dalam menghasilkan karya terjemahan Indonesia-Inggris (karya sastra Indonesia-Inggris) berjudul “Jatisaba”, sebuah novel yang sarat dengan istilah dan ekspresi budaya Jawa (Banyumasan). Karena penerjemah adalah mediator budaya, penelitian ini bertujuan untuk mengungkap lebih jauh strategi seorang penerjemah dalam mentransfer karya bahasa Indonesia yang sarat akan istilah budaya ke dalam bahasa Inggris. Sebuah praktik yang dijalankan oleh agen penerjemahan sastra yang berpotensi memungkinkan pembaca internasional untuk mengapresiasi karya pengarang Indonesia dan mengenal lebih jauh identitas budaya yang dilakukan melalui karya sastra. Agen dalam penelitian ini merujuk pada seorang penerjemah yaitu Christopher Allen Woodrich, seorang penutur asli bahasa Inggris yang dianggap memiliki modal budaya yang cukup pada sastra Indonesia karena latar belakang akademisnya. Sebagai kerangka pemikiran, kajian sosial budaya ini mengadaptasi konsep strategi Bourdieus dalam teori produksi budaya. Sedangkan secara metodologis, wawancara dan pemilihan dokumen digunakan sebagai teknik untuk memperoleh data. Di akhir penelitian, ditemukan bahwa penerjemah menggunakan strategi yang memungkinkan pembaca memahami karya yang diterjemahkan, sekaligus tetap menjaga warna lokalnya. Strategi ini berpotensi membantu meningkatkan visibilitas penerjemah. Selain itu, penelitian ini juga mengungkap bagaimana modal budaya penting bagi praktik penerjemahan.
An Analysis of The Language Variations of Luwunese Through Speech Acts (Fokus: Luwu, North Luwu, and East Luwu)
Authors: Surahim Irsyam , Ramli Aswadi
Published: January 2024

The main objectives of this research were to determine the differences of language variation in the use of regional language  especially  Luwu, North Luwu and East Luwu in South Sulawesi area. The descriptive qualitative research method was applied by the researcher. The research was conducted at Luwu, North Luwu and East Luwu. The researcher describes that variety of luwu, North Luwu and East Luwu. In this research the researcher using purposive sampling, the researcher observed and interviewed all of the respondents  who from Luwu, North Luwu, and East Luwu. The researcher used video recording and field notes to conduct observation. Respondents’ activities and attitudes social was captured on video. Meanwhile, the researcher used field notes to obtain more accurate data. Based on the observation that The language variation in Luwu were different with the language  North Luwu people and East Luwu, because the variation Luwu language has same the similarity language spoken Buginese people and near also from the land of Buginese are. There were several factors that caused language variations of Luwunese including internal factors such as self perception, perception of language, language difficulties , and external factors such as social judgment. The factors divided into three categories: linguistic factors, which cover linguistic difficulties, psychological factors, and environmental factors. As a result, it is suggested that the researcher and reader get to know more about the language variations of Luwunese. By becoming acquainted with the language variations of Luwunese, the people has to study about the language of variety, in order that can helping communicate with the  kind.
Pendampingan Pengembangan Media Pembelajaran Dua Dimensi bagi Guru SMA Negeri 9 Makassar
Authors: Saparuddin Saparuddin , Kaswar Andi Baso , Patongai Dian Dwi Putri Ulan Sari
Published: January 2024

Salah satu faktor penting dalam proses pembelajaran adalah media pembelajaran. Media pembelajaran dapat menjadi perantara suatu pesan agar sampai kepada peserta didik. Pentingnya peran media dalam pembelajaran mengharuskan pendidik harus terampil dalam menyiapkan, membuat dan mengguanakan media pembelajaran. Media pembelajaran membantu dalam penyampaian materi pembelajaran yang kompherensif, inovatif, dan menarik minat, dan antusisasme peserta didik. Tujuan kegiatan ini untuk meningkatkan pengetahuan dan keterampilan guru dalam membuat media dan sumber belajar dua dimensi. Metode pelaksanaan pengabdian pelatihan dan pendampingan penelitian mengacu pada dua kegiatan rancangan. Pertama, persiapan, sosialisasi, analisis kebutuhan, dan administrasi. Kedua, pelaksanaan pelatihan pendampingan. Capaian dari kegiatan ini adalah guru akan terlatih atau memiliki pengetahuan dan keterampilan dalam membuat media presentasi yang menarik seperti infografis, power point, serta peta konsep/Mind Mapping berbasis aplikasi
Pelatihan dan Pendampingan Wirausaha Bagi UMKM Singkong Keju Beku Berbasis Digital
Authors: Al Anshori Fitrah , Hidayat Wahyu , Sohriati Eva
Published: January 2024

Mitra pada kegiatan program kemitraan masyarakat merupakan UMKM singkong keju beku yang telah membuat produk produk dan akan diberikan Pelatihan dan Pendampingan Wirausaha Bagi UMKM Singkong Keju Beku Berbasis Digital, Pelaksanaan kegiatan dilakukan dengan memberikan pelatihan wirausaha berbasis Digital terdiri dari pelatihan penyusunan merk produk dan pendaftarannya, pelatihan membangun merk dan brandingnya, pelatihan pemasaran secara digital dan pengelolaan keuangan dengan baik. Pelatihan dilaksanakan selama bulan september 2022. Hasil dari kegiatan program kemitraan masyarakat berupa terjadi peningkatan pengetahuan dan keterampilan mitra pada kegiatan pelatihan dan pendampingan UMKM singkong keju beku dalam hal pentingnya merk produk, pentingnya memiliki branding sendiri, pentingnya mendaftarkan merk di kemenkumham, dan pentingnya melakukan pemasaran secara digital.
Peningkatan Pengetahuan Masyarakat terhadap Kosmetika yang Aman di Majelis Taklim Al-Jihad, Argapura, Kota Jayapura
Authors: Bakri Nur Fadilah , Lingga Irene S. , Dewi Krisna
Published: January 2024

Kosmetika telah menjadi salah satu kebutuhan primer wanita untuk saat ini. Karena kosmetika digunakan secara rutin maka perlu diperhatikan bahan-bahan yang terkandung dalam kosmetika tersebut, agar yang menggunakan kosmetika terhindar dari bahaya atau efek samping dari bahan-bahan berbahaya yang terdapat didalam kosmetika. Pengabdian ini dilakukan kepada ibu-ibu majelis taklim Al Jihad, Argapura, Kota Jayapura sebanyak 25 orang. Kegiatan ini bertujuan memberikan edukasi kepada ibu-ibu majelis taklim tentang bahaya penggunaan kosmetika secara sembarangan dan memberikan informasi mengenai bahan-bahan berbahaya yang terdapat dalam kosmetika. Peningkatan pengetahuan peserta diukur melalui jawaban pada kuisioner yang dibagikan sebelum (pretest) dan setelah (posttest) pemberian materi. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan peserta terkait bahaya penggunaan kosmetika secara sembarangan dan bahan-bahan berbahaya pada kosmetika. Selain itu peserta juga telah mengetahui cara mengecek produk yang telah memiliki nomor ijin edar BPOM. Ibu-Ibu majelis taklim juga berkomitmen menjadi agen edukasi kepada masyarakat di lingkungan sekitar terkait dengan penggunaan kosmetika yang aman. Temuan penilitian ini adalah masih banyak masyarakat yang belum bisa memilih kosmetika secara aman. Hal ini disebabkan karena kurangnya pengetahuan tentang bahan-bahan berbahaya yang terdapat dalam kosmetika dan ciri-ciri kosmetika yang aman.
Pendampingan Pemanfaatan Akun Belajar.ID Jenjang Sekolah Dasar Kota Palopo
Authors: Hardiana Hardiana , Akramunnisa Akramunnisa , Mahyuddin Mahyuddin
Published: January 2024

Tujuan yang ingin dicapai pada kegitan pengabdian ini adalah melaksanakan edukasi tentang pemanfaatan akun belajar.id kepada operator jenjang Sekolah Dasar lingkup Dinas Pendidikan Kota Palopo. Mitra sasaran peda kegiatan abdimas adalah semua pendidik yang ada pada Sekolah Dasar yang sudah mengaktifkan akun belajar.id nya sehingga mereka dapat mengakses semua flatform dari Kementerian Pendidikan, Kebudayaan, Riset dan Teknologi. Instrumen yang digunakan adalah laptop untuk mengakses akun Belajar.ID. Pengumpulan data melalui observasi. Teknik analisis data yaitu kualitatif deskriptif. Untuk mencapai tujuan dan target ini adalah melakukan pendampingan bersama dengan Dinas Pendidikan terhadap semua operator jenjang Sekolah Dasar lingkup Dinas Pendidikan Kota Palopo. Kegiatan pengabdian ini meliputi: mengedukasi mengenai akun belajar.id, tujuan akun belajar.id dan manfaat akun belajar.id. Setelah pengabdian ini selesai dilaksanakan maka, kami berharap agar semua operator Sekolah Dasar yang ada di Kota Palopo dapat memahami serta membantu para pendidik di Sekolahnya masing-masing untuk mengaktivasi akun belajar.id pendidik di Sekolahnya masing-masing. Temuan dalam pelaksanaan Abdimas adalah pelaksanaan edukasi akun belajar.ID sangat bermanfaat bagi semua guru
Pelatihan Jaringan Dasar Sharing Data dan Remote Access Menggunakan Aplikasi VNC
Authors: Siaulhak Siaulhak , Kurniadi Wisnu , Syafriadi Syafriadi
Published: January 2024

Berkembang Pesatnya kemajuan teknologi saat ini membuat manusia semakin belajar dan belajar untuk memenuhi kebutuhan yang serba ber teknologi. Semakin pesatnya kemajuan teknologi saat ini, semakin bertambahnya juga kebutuhan manusia. Pelatihan Jaringan Dasar Sharing Data dan Remote Access Menggunakan Aplikasi VNC bertujuan untuk meningkatkan keterampilan para siswa-siswi khususnya dalam penguasaan jaringan dasar sharing data menggunakan kabel LAN dan remote access menggunakan aplikasi VNC untuk memudakan dalam pekerjaan. Mitra sasaran pada kegiatan pengabdian kepada masyarakat yaitu siswa-siswi SMA Negeri 2 Luwu. Pengumpulan data melalui evaluasi atau menindak lanjuti pencapaian hasil pelaksanaan kegiatan pelatihan kepada peserta. Hasil kegiatan pelatihan ini dapat meningkatkan keterampilan para siswa-siswi khususnya dalam penguasaan jaringan dasar sharing data menggunakan kabel LAN dan remote access menggunakan aplikasi VNC untuk memudakan dalam pekerjaan. Selama kegiatan dilaksanakan siswa-siswi menerima dan mendengarkan materi yang disampaikan oleh pemateri dengan baik sehingga Ketika siswa-siswi melakukan praktek langsung mereka langsung paham apa yang harus dilakukan dan didampingi oleh tim pelaksana kegiatan. Setelah melakukan praktek dengan didampingi leh tim pelaksana kegiatan, siswa-siswi jadi mengetahui cara melakukan sharing data menggunakan kabel LAN dan cara meremote access menggunakan aplikasi VNC.
Pelatihan dan Pendampingan Pembuatan Yoghurt Bagi Ibu PKK Desa Sicini
Authors: Khaerunnisa Khaerunnisa , Saenab Sitti , Zahrah Siti , Faisal Faisal , Kurnia Nani
Published: January 2024

Tujuan dari pelatihan ini adalah untuk memberikan pengetahuan dan melatihkan keterampilan ibu PKK dalam pembuatan yoghurt serta memberikan informasi tentang manfaat yoghurt dan peluang usaha. Kegiatan dilakukan dengan memberikan materi serta melakukan praktik pengolahan susu menjadi olahan pangan yaitu yoghurt. Metode dalam pelatihan ini adalah ceramah, diskusi, tanya jawab, dan pelatihan dalam pembuatan yoghurt. Diikuti oleh 20 orang peserta ibu PKK Desa Sicini. Hasil yang didapat setelah pelatihan ini yaitu peserta antusias dan paham cara membuat yoghurt, sehingga masyarakat dapat mengaplikasikan dan diharapkan dan dapat menjadi usaha bersama untuk meningkatkan kesejahteraan masyarakat terutama dilingkungan kecamatan parigi
Optimizing the Freedom Teaching Platform Application (PMM) Through the Cluster PAUD Learning Community
Authors: Jumarniati Jumarniati , Fitriani Fitriani
Published: January 2024

Dedication program public this to give experience to Head Schools and PAUD Teachers in use independent platform application teach. Activity devotion done by the author Work The same Department of Education and Culture, City of Pare Pare. Problems main partners is an unprepared institution in accessing PMM applications and uses existing features inside. Objective from activity this is to share information related to the Merdeka Teaching Platform Application and participants capable access and complete topic as well as module until understanding method upload action real. Main partner in devotion This is Community Fostered PAUD Group Ujung sub district and sub district afternoon. Method accompaniment This consists of stage analysis needed partners, mentoring PMM optimization and evaluation achievement activity. Assistance results obtained that participants can access the Merdeka Mengajar Platform, have account study, do topics as well as existing modules in the PMM application as well know how to upload reports.
Pelatihan Aplikasi Webmap Sebagai Upaya Penanggulangan Banjir Pada Sektor Pertanian Desa Jambu Kecamatan Bajo Kabupaten Luwu
Authors: Amir Baso , Fitriani Fitriani , Amri Ariani
Published: January 2024

Kondisi alam semakin tidak pasti dan sulit diprediksi akibat perubahan pola curah hujan dan iklim. Curah hujan yang berlebihan dapat menyebabkan banjir yang merugikan sektor pertanian. Banjir merupakan tantangan alam yang sering dihadapi di sektor pertanian. Tantangan tersebut dihadapi sebagian besar lahan pertanian di Luwu, termasuk di Desa Jambu. Dampak banjir pada lahan sawah di lokasi tertentu yang semakin meluas dan intensif dari tahun ke tahun menimbulkan kerugian yang cukup besar bagi petani. Tujuan dari kegiatan ini adalah untuk memetakan lahan pertanian yang terkena banjir secara partisipatif dengan bantuan aplikasi Webmap. Metode pelaksanaan kegiatan ini meliputi tahap persiapan, tahap pelaksanaan, dan tahap monitoring dan evaluasi. Hasil kegiatan menunjukkan bahwa peserta sangat antusias dengan program kegiatan ini, terbukti dengan respon positif berupa kehadiran 96% peserta pelatihan dan aktifnya kegiatan diskusi selama sosialisasi dan pelatihan berlangsung. Usai pelatihan, para peserta juga mengharapkan tindak lanjut berupa pendampingan dari tim pengabdi untuk meningkatkan keterampilan dengan aplikasi Webmap di bidang lain. Kegiatan ini diharapkan dapat menjadi solusi yang dapat ditawarkan untuk memberikan sistem peringatan dini berbasis pemetaan sehingga penyampaian informasi tentang banjir dapat lebih cepat tersampaikan kepada masyarakat khususnya masyarakat yang memiliki mata pencaharian pertanian untuk mewaspadai bencana banjir.
Lokakarya Pembelajaran Daring Berbasis Learning Manajemen Sistem melalui Kursus Digital
Authors: Zulham Muhammad , Sukmawati Sukmawati , Herdiana Besse
Published: January 2024

Perhatian utama dalam pelatihan Teknologi Informasi (TI) adalah bahwa pelatihan berbasis TI berfokus pada aspek teknis atau aspek point and click dari platform sistem manajemen pembelajaran (LMS) dan perangkat lunak peningkat pedagogi tanpa memperhatikan isi kursus. Pendekatan Lokakarya Pelatihan Kursus Digital (LPKD) yang dibahas dalam artikel ini mengatasi masalah ini dengan mendukung pendekatan yang mengutamakan konten. Pendekatan LPKD merupakan sebuah inisiatif di Universitas Cokroaminoto Palopo yang bertujuan untuk mendukung lembaga melalui proses transisi dari kursus tatap muka (F2F) ke pengajaran Daring. Staf pengajar yang berpartisipasi mengikuti seminar selama seminggu dengan konten kursus tradisional dan pulang dengan konten digital yang dialihkan ke platform LMS yang sesuai. Artikel ini dimaksudkan untuk merangsang refleksi tentang perlunya program dan kegiatan pengembangan profesional yang sistematis untuk membantu Dunia pendidikan tinggi dalam proses transisi dari kursus tradisional ke Daring.