bluuebunny/crossref_metadata_2025 huggingface dataset:
Entrevista al Magistrado Froylán Muñoz Alvarado
Authors: Ramírez Espinoza Martha Aurora
Published: October 2023

El Magistrado Froylán Muñoz Alvarado, se desempeñó como Juez de Distrito y Magistrado Unitario en el estado de Sinaloa, y Juez de Distrito en el estado de Chiapas. Cursó la Licenciatura en Derecho y Maestría en Investigación, en la Universidad Michoacana de San Nicolás de Hidalgo. Asimismo, estudió la especialidad en Derecho Penal, en la Universidad de Salamanca, España. Realizó el Doctorado en Derecho Penal y Política Criminal, en el Instituto Nacional de Ciencias Penales. (INACIPE). También tiene un Doctorado enDerecho Público, en la escuela Libre de Derecho en el Estado de Chiapas e igualmente se encuentra concluyendo el programa de “Doctorado en Ciencias Jurídicas”, en la Facultad de Derecho de laUniversidad Michoacana de San Nicolás de Hidalgo. Actualmente, está iniciando el “Doctorado en Derecho”, en la Facultad de Derecho de la Universidad Nacional Autónoma de México”.
Capítulo Segundo. Presupuesto de Egresos y Gasto Público como Instrumentos de Intervención del Estado en la Economía
Authors: Morales Mendoza Héctor Benito
Published: October 2023

Concluido el desarrollo y análisis de las contribuciones teóricas más destacadas que aportan importantes elementos para explicar la presencia, intervención y comportamiento del Estado en la economía, que como hemos visto es variable dependiendo de la orientación doctrinaria económica imperante, nos ocuparemos ahora del análisis del presupuesto de egresos y del gasto público como importantes elementos de la actividad financiera estatal de carácter instrumental, de la que ahora se ocupa la Economía del Sector Público con independencia de la Economía Política, mediante los cuales el Estado interviene en la economía, a la par de la planeación, del sector paraestatal y de las políticas públicas, entre otros instrumentos ya que si bien en el Estado del laissez faire las funciones a su cargo eran las primordiales liberales, en la etapa del Estado Benefactor se acentuaron y crecieron en número, importancia, proyección e intensidad, para atenuarse denueva cuenta en el transcurso de las tres últimas décadas por efecto de la globalización y el neoliberalismo a conveniencia del mercado o de ciertos sectores de la sociedad.
Editorial
Authors: Carrancá y Rivas Raúl
Published: October 2023

En esta ocasión, la Revista del Posgrado en Derecho, se engalana con una excepcional serie de artículos, muchos de ellos relativos a novedosísimas temáticas.
Concepto de Deontología y Régimen Deontológico Aplicable a la Abogacía en España
Authors: Pérez Fernández Francisco
Published: October 2023

El objetivo de este ensayo es, en primer lugar, realizar una labor de investigación acerca del origen del término deontología, a fin de lograr entender el auténtico sentido del mismo. Además, analizaremos el interesante recorrido histórico que ha seguido la deontología a lo largo del tiempo y que la ha llevado a convertirse en un conjunto de normas jurídicas indispensables de cara a garantizar ciertos derechos. En el desarrollo de este análisis prestaremos especial atención a lo acontecido en España respecto a la creación de las normas deontológicas encargadas de regir el ejercicio de la abogacía, exponiendo también la actual estructura normativa que a día de hoy conforma el marco jurídico de tipo deontológico aplicable a los abogados.
Studies on Properties of Sisal Fiber Reinforced Self Compacting Concrete
Authors: Samy M. Aravinda , Ramasamy Dr. V. , Selvakmar S.
Published: October 2023

Abstract: To evaluate the mechanical properties of self-compacting concrete (M30) with sisal fibers. Self-compacting concrete (SCC) mixes are produced by replacing the cement with Fly ash and with addition of sisal fiber of 0, 0.5%, 1% and 1.5% and length of fibers considered are 5mm, 10mm, and 20mm to the SCC concrete. Sulphonated naphthalene Formaldehyde condensates-based SP is used as water reducing agent. Compressive strength of SCC mix has to be determined at 7, 14 and 28 days. Flexural strength of SCC mix has to be determined at 14 and 28 days. Impact strength of SCC mix has to be determined at 28 days.
A Global Warming and Climate Change is a Major Threat to the Earth and Environment in the Near Future
Authors: Bangar Shubham
Published: October 2023

Abstract: This review article presents compelling evidence that global warming has already begun, and it requires our immediate attention. The accumulated evidence of significant and alarming climate changes on Earth has rapidly grown, especially in the last three decades. Rather than relying primarily on theoretical models, the reality of global warming is supported by an extensive body of observations from various sources. The focus of climate research has shifted from proving global warming's existence to understanding its causes. While it may be challenging to predict the exact extent of damage from global warming, it is clear that its harmful effects on the climate will far outweigh any potential benefits. There is a high probability that human-generated greenhouse gases, particularly carbon dioxide, are the primary drivers of documented global warming and climate change. It is emphasized that much can be done now to mitigate the effects of global warming and associated climate change. The main obstacles in addressing this issue are not the unavailability of technology but the lack of sufficient incentives to implement these technologies more aggressively. This highlights the need for policy measures and collective efforts to tackle the challenges posed by global warming effectively
A Phytochemical study of Bodhivriksha Twaka
Authors: Jitarwal Dr. Ramnarayan , Garg Dr. Naresh , Sharma Prof. Dr. Om Prakash
Published: October 2023

Abstract: Bodhivriksha is an important drug described in detail in Ayurvedic classical texts. Ashwatha, a classical Ayurvedic polyherbal formulation is used for the treatment of Rakatpitta Vikaras, Neelameha, Kaphavikaras, Vatrakta and Yoni Doshas. Ashwatha is used in the form of both single drug and compound formulations. The phytochemical analysis showed the presence of alkaloids, saponins, tannins, terpenoids, steroid, flavonoids and carbohydrates. The present study was to evaluate the phytochemical screening of extracts of Twaka of Bodhivriksha. Study has been shown that this medicinal plant can be used as pharmaceutical adjuvants in the formulation of various dosage forms.
A Tensorized Hierarchical Graph Attention Network for Stock Market Forecasting
Authors: Reddy Yajanth Rami
Published: October 2023

Abstract: Stock market forecasting is a tough mission because of its complex and dynamic nature. Deep learning models have recently been proven to be successful at stock market predictions. Traditional deep learning models, however, frequently disregard the hierarchical structure and temporal relationships of the stock market. Here, we introduce the StockTensor, a brand-new tensorized hierarchical graph attention network for stock market forecasting. StockTensor models the hierarchical structure of the stock market data by constructing a hierarchical graph of stocks. At each level of the hierarchy, StockTensor uses a graph attention network to learn the relationships between stocks and aggregate the information from neighboring stocks. StockTensor also models the temporal dependencies of the stock market data by using a recurrent neural network. The recurrent neural network learns to predict future stock prices based on the current stock prices and the historical stock prices. We evaluate StockTensor on two real-world stock market datasets. The results show that StockTensor outperforms several stateof-the-art stock market forecasting models.
Market Competition in Modern Franchise Retail Business with Traditional Retail Business in Saddu Al-Zari'ah Approach
Authors: Fauziah Fauziah , Arif Widyantono
Published: October 2023

Purpose: This article focuses on examining analysis in Islamic law on the existence of Alfamart and Indomaret minimarkets in Makassar City Methodology/approach: This research is a type of qualitative descriptive research, namely a writing procedure that produces descriptive data Findings: Based on the results of the study, it can be concluded that the existence of Alfamart and Indomaret minimarkets in their trading activities is reviewed in Islamic law including monopoly. Practical implications: As well as in its trading activities, it does not pay attention to business competition and the principle of justice in Islamic law. To prevent the expansion of the two minimarkets, Saddu Al-Zari'ah approach is needed so as not to have a bad impact on its competitors, namely grocery stores and traditional markets. Originality/value: Originality of this research is the subject using a Islamic law for trading activites.
Growth Opportunity, Capital Structure And Profitability On Company Value
Authors: Nufyar Ahmad , Mulyani Erly
Published: October 2023

Purpose: This study has a purpose to decide the impact of growth opportunity, capital structure, and Profitability on firm worth in metal area organizations recorded on the Indonesia Stock Exchange for the period 2017-2021. Methodology/approach: This examination is a kind of causal exploration that utilizes various straight relapse investigations to test the proposed speculation. The population in this study are metal organizations and so forth that are recorded on the Indonesia Stock Exchange in the 2017-2021 period, which are 17 organizations. The testing procedure utilized was purposive examining so the quantity of tests utilized in this review was 70 examples Findings: Wellsprings of information utilized in this study are information sources which are information accessible in the wake of being collected by different gatherings. The aftereffects of this study demonstrate that growth opportunities significantly affect firm worth, while capital structure and profitability significantly affect firm worth. Then growth opportunities, capital structure, and profitability at the same time affect firm worth Practical implications: For additional exploration, it is normal to look at different factors other than Growth Opportunity, Capital Structure, and Profitability and is supposed to build the example to be concentrated so the outcomes obtained are more influential. Originality/value: This research adds a profitability variable to differentiate it from previous research
Riscos Associados ao Uso Não Racional de Anti-Inflamatórios Não Esteroides
Authors: Marinho Ana Maria Oliveira de Sousa , Oliveira André Costa Ferreira de , Lima Glenda Maria Diógenes Santiago de , Bachur Tatiana Paschoalette Rodrigues
Published: October 2023

Os anti-inflamatórios não esteroides (AINEs) são a classe de medicamentos mais utilizada no mundo. A venda livre destes fármacos, sem necessidade de prescrição médica, contribui para a ingestão de doses elevadas e excessivas dessas drogas, o que está associado a diversos efeitos sistêmicos associados à sua toxicidade. Neste contexto, o objetivo do presente estudo foi revisar a literatura científica a fim de elucidar os riscos associados ao uso não racional dos AINEs. Para tal, foi conduzida uma pesquisa bibliográfica nas bases de dados MEDLINE e LILACS. Após a seleção de estudos publicados entre 2018 e 2023, foram incluídos dez artigos na presente revisão. Os resultados dos trabalhos analisados indicam efeitos adversos associados aos sistemas gastrointestinal, dermatológico, neurológico, cardiovascular, renal, hematopoiético, interferindo nos fatores de coagulação, além dos riscos da ingestão de uma dose supra terapêutica na gestação. Portanto, é indiscutível a importância do esclarecimento desses riscos para a população, uma vez estes efeitos adversos interferem diretamente na qualidade de vida dos pacientes. Além disso, os profissionais da saúde precisam estar sempre atentos para os medicamentos utilizados pelos seus pacientes, suas doses e o tempo de utilização, para prevenir a toxicidade causada pelos AINEs.
Intoxicação por Aconitum
Authors: Martins Sara dos Santos , Magalhães Clara Botelho , Carmo Julia Mendes do , Bachur Tatiana Paschoalette Rodrigues
Published: October 2023

O gênero Aconitum (Ranunculaceae) possui mais de 300 espécies em todo o mundo, sendo plantas conhecidas por possuírem poderosos compostos alcaloides e utilizadas, principalmente, na medicina chinesa, para diversos fins terapêuticos. No entanto, o uso de aconitum para fins medicinais deve ser feito com extrema cautela sob supervisão médica, devido à sua toxicidade. O objetivo do presente estudo foi revisar a literatura científica a fim de elucidar os efeitos da toxicidade por acônito, evidenciando os mecanismos fisiopatológicos que desencadeiam esses efeitos. Para tal, foi conduzida uma pesquisa bibliográfica nas bases de dados MEDLINE, LILACS, Web of Science e EMBASE. Após seleção dos estudos publicados entre 2009 e 2022 foram incluídos 14 artigos na presente revisão. Os trabalhos analisados indicam que os principais danos causados por acônito estão associados à cardiotoxicidade e a neurotoxicidade.
Quais as consequências físicas do uso de substâncias anabolizantes para aumentar o rendimento de atletas?
Authors: Guedes Vitor Cavalcante , Machado Maria Tereza Pontes , Bachur Tatiana Paschoalette Rodrigues
Published: October 2023

Os esteroides anabólicos androgênicos (EAA) aumentam a força e a resistência e diminuem a fadiga de seus usuários. Porém, diversas pesquisas já foram conduzidas para demonstrar os efeitos nocivos dessas substâncias à saúde, como alteração hormonal, cardíaca, comportamental e estética. O objetivo desta pesquisa foi elucidar e informar acerca das consequências neurológicas, cardíacas, gonadais e hepáticas do uso crônico dos esteroides anabolizantes androgênicos. Para tal, foi realizada uma busca nas bases de dados MEDLINE e LILACS, tendo sido selecionados 17 artigos para construir esta revisão. O uso de EAA, principalmente, quando excessivo e prolongado, é extremamente prejudicial à saúde dos usuários e causa diversos efeitos colaterais, incluindo prejuízos cardiovasculares, gonadais, hepáticos e neurológicos que podem ser fatais. É de suma importância que os profissionais da saúde tenham conhecimento das dimensões do uso de EAA e da complexa conexão entre o uso crônico dos anabolizantes com o organismo humano. No entanto, apesar dos dados citados, ainda existe uma escassez de estudos retrospectivos abordando o uso não terapêutico de EAA, além de carência de dados epidemiológicos que indiquem a extensão do consumo e dos danos do uso destas substâncias.
The Harmonizing Perspective of Theoretically Theological (Aqidah)-Based and Realistically Fiqhi-Based in Dealing with Pandemics and Plagues
Authors: Bichi Mohammed Abdelhalim
Published: October 2023

This research discusses the issue of pandemics in relation to the perceptions and views of Muslim theologians on the issues of evil and agony. Besides, it discusses the cause-effect relationship between infection and pandemics. It investigates how affliction affects humans as short and long-term chastisement as argued by the Mu’tazila, Asha’irah and Sufis on one hand and other Muslim philosophers on the other. The study discusses how such pandemics are addressed by Muslim scholars’ jurisprudential interpretations in line with worship, financial and urban countermeasures. It also discusses some essential medical and spiritual approaches to be used as preventative countermeasures against pandemics. The study concludes that it is “faith” that motivates humans to be patient and that instills in them essential values and principles for happiness and self-satisfaction.
ELABORACIÓN DE UN CURSO DE POSGRADO SOBRE BIOÉTICA DE LA INVESTIGACIÓN EN LA UNIVERSIDAD DE COSTA RICA
Authors: Granados-Zúñiga Jorge
Published: October 2023

Se describe el proceso de elaboración de un curso sobre bioética de la investigación desde una perspectiva de derechos humanos y con una base metodológica de análisis de problemas seleccionados. Se discute la relevancia de este abordaje en términos de los conocimientos, habilidades y actitudes básicas que se desea inculcar en los estudiantes, así como el papel del docente como facilitador del diálogo, el debate y la discusión democráticos. La propuesta plantea sesiones presenciales y virtuales con objetivos específicos, contenidos y bibliografía recomendada. Se enfatiza, especialmente, que el desarrollo de la propuesta parte de una contextualización costarricense, con el fin de procurar identificar instituciones y prioridades de investigación.
MONITOREO PEDAGÓGICO DE CURSOS EN LÍNEA, UNA PRÁCTICA PARA PROMOVER LA CALIDAD EN LA UNED
Authors: Mora-Vicarioli Francisco , Castro-Granados Alejandra
Published: October 2023

La Universidad Estatal a Distancia (UNED) de Costa Rica es una institución de educación superior que, actualmente hace uso intensivo de algunos medios tecnológicos, en particular, las plataformas de aprendizaje en línea. La implementación de dicha herramienta amerita la creación de mecanismos que promuevan y eleven la calidad de los cursos en línea, prestando atención a criterios específicos previamente definidos. Una estrategia importante para velar por el cumplimiento de dichos criterios es el monitoreo o supervisión pedagógica de los cursos en línea, en el que se realiza una revisión del cumplimiento del profesorado en cuanto a la estructura, la mediación y la atención de espacios de comunicación tendientes a brindar la realimentación necesaria para la mejora continua. En este artículo, se presentan los resultados de una investigación de carácter cualitativo, cuya unidad de análisis son todos aquellos tutores que han formado parte del proceso de monitoreo pedagógico, así como los ejecutores de dicha actividad; en donde, la información fue recolectada por medio de un cuestionario en línea. En ella se busca analizar la relevancia que tiene el monitoreo para las instancias de la universidad y los beneficios que puede aportar a la mejora de los cursos en línea, como parte de la experiencia desarrollada en la UNED. Afortunadamente, en la totalidad de las respuestas recibidas se consideró de alto valor dicha actividad, al posibilitar el mejoramiento continuo, y ofrecer un mejor proceso de aprendizaje a los estudiantes, por lo cual, se contempla que la práctica del monitoreo puede resultar un referente para aquellas instituciones que utilizan la modalidad virtual y desean mejorar la supervisión académica en dichos entornos, así como la realimentación que se le puede brindar al docente en su quehacer.
Acute Myocardial Infarction Mimicking Hypertrophic Cardiomyopathy
Authors: Carvalho Pedro Rocha , Ferreira Catarina , Fontes José Paulo , Moreira José Ilídio
Published: October 2023

This case study presents a 53-year-old male with a history of
myopericarditis who experienced retrosternal pain, shortness of breath,
and sweating. Initial electrocardiogram indicated ST segment elevation
in the inferior leads and T-wave inversion in the lateral leads.
Echocardiogram exhibited marked hypertrophy of the posterior wall (18mm)
and moderate hypertrophy of the infero-septal wall. While biventricular
systolic function was preserved, both the posterior wall and
infero-septal wall displayed regions of hypokinesis. Following
admission, the patient underwent cardiac catheterization, revealing
thrombotic occlusion of the second obtuse marginal branch. Subsequent
monitoring showed no recurrence of chest pain or arrhythmias, and the
patient’s condition remained stable. A follow-up echocardiogram
displayed displayed hypertrophy of the posterior wall (17mm) and a
slight increase in infero-septal wall thickness (13mm). Left ventricular
systolic function exhibited mild depression, characterized by an average
ejection fraction of 44%. Cardiac MRI after three months revealed
normalized wall thickness, persisting regional dysfunction, and
pericardial effusion. This case highlights the dynamic nature of
ventricular wall thickening during acute artery occlusion, indicating
the role of wall edema. It emphasizes the importance of comprehensive
imaging for accurate diagnosis and management of complex cardiac
conditions.
Long-Term Outcomes of Cardioneuroablation with and without Extra-Cardiac Vagal Stimulation Confirmation in Severe Cardioinhibitory Neurocardiogenic Syncope
Authors: Pachon-M Jose , Pachon Enrique Indalecio , Pachón Carlos , Pena Tomás , Lobo Tasso J. , Pachon Juan , Higuti Christian , Zerpa Juan , Pachon Maria , Ortêncio Felipe , Osório Thiago Guimarães , Peixoto Luis
Published: October 2023

Background Cardioneuroablation (CNA) is a novel therapeutic
approach for functional bradyarrhythmias, specifically neurocardiogenic
syncope or atrial fibrillation, achieved through endocardial
radiofrequency catheter ablation of vagal innervation, obviating the
need for pacemaker implantation. Originating in the nineties, the first
series of CNA procedures was published in 2005. Extra-cardiac vagal
stimulation (ECVS) is employed as a direct method for stepwise
denervation control during CNA. Objective This study aimed to
compare the long-term follow-up outcomes of patients with severe
cardioinhibitory syncope undergoing CNA with and without denervation
confirmation via ECVS. Method A cohort of 48 patients,
predominantly female (56.3%), suffering from recurrent syncope (5.1±2.5
episodes annually) that remained unresponsive to clinical and
pharmacological interventions, underwent CNA, divided into two groups:
ECVS and NoECVS, consisting of 34 and 14 cases, respectively. ECVS
procedures were conducted with and without atrial pacing.
Results Demographic characteristics, left atrial size, and
ejection fraction displayed no statistically significant differences
between the groups. Follow-up duration was comparable, with 29.1 ± 15
months for the ECVS group and 31.9±20 months for the NoECVS group
(p=0.24). Notably, syncope recurrence was significantly lower in the
ECVS group (2 cases vs. 4 cases, Log Rank p=0.04). Moreover, the Hazard
ratio revealed a five-fold higher risk of syncope recurrence in the
NoECVS group. Conclusion This study demonstrates that
concluding CNA with denervation confirmation via ECVS yields a higher
success rate and a substantially reduced risk of syncope recurrence
compared to procedures without ECVS confirmation.
An ISGW Millimeter-Wave Filtering Antenna with Four Controllable Radiation Nulls
Authors: Hui Ming , Li Liang , Jiang Pei , Zhang Meng , Wang Yongjie
Published: October 2023

This paper presents a millimeter-wave Integrated Substrate Gap Waveguide
(ISGW) filtering antenna with four controllable radiation nulls, two on
each of its upper and lower stop bands. These radiation nulls can be
adjusted by manipulating the dimensions of the stepped-impedance
resonators (SIRs), complementary U-slots, and passive coplanar parasitic
patches. This filtering antenna has the advantages of separately
controllable radiation nulls and flexible adjustment of selectivity and
gain curve roll-off. The simulation results demonstrate that the antenna
operates at a center frequency of 25.4 GHz, with a relative bandwidth of
14.3% (23.76-27.04 GHz), and achieves a realizable average gain of 7.6
dBi.
Endo-Epicardial ablation of incessant slow monomorphic ventricular tachycardia originating from the left ventricular summit in a patient with cardiac resynchronization therapy defibrillator
Authors: Elizalde-Uribe Ivan Alejandro , Andrade-Cuellar Elias Noel , Robledo-Nolasco Rogelio , Morales-Portano Julieta D. , Manrriquez-Trasviña Carlos , López-Trejo Felipe Israel , Figueroa-Zelaya Ariel Alberto , Lara-Vargas Jorge A. , Rodríguez-Diez Gerardo , Ortiz-Avalos Martin , Gómez-Alvarez Enrique
Published: October 2023

Slow ventricular tachycardia (VT) in patients with ICDs is uncommon, and
its impact is considered minor. However, understanding its long-term
risk is crucial since high-risk patients might benefit from prophylactic
ablation and device programming to reduce inappropriate ICD therapies.
We present the case of a 69-year-old man with a history of acute
myocardial infarction and aborted sudden cardiac death in 2002 underwent
angioplasty with stent placement in the anterior descending artery and
implantation of a CRT-D. He remained in NYHA functional class I. In
2019, he experienced two appropriate shocks for ventricular tachycardia
(VT), and in 2021, three sustained VT events within 24 hours. A catheter
ablation was decided to treat the VT, with a successful endo-epicardial
approach. After 48 hours without VT recurrence, he was discharged. In
the presented case of ischemic cardiomyopathy, an endo-epicardial
approach was crucial for successful ablation of VT originating from the
left ventricular summit. This case emphasizes the need for
individualized ablation strategies in patients with incessant slow VT
and ICDs.
Multi-Omics Panoramic Analysis of HBV Integration, Transcriptional Regulation，Translation, and Epigenetic Modifications in the Classical HBV-Integrated Cell Line PLC/PRF/5
Authors: Chen Xiangmei , Guan Guiwen , Abulaiti Abudurexiti , Chen Chia-Chen , Gu Zhiqiang , Yang Jing , Zhang Ting , Chen Xiaojie , Zhou Zhao , Lu Fengmin
Published: October 2023

Background: The clearance or transcriptional silencing of
integrated HBV DNA is crucial for achieving a functional cure in
patients with chronic hepatitis B (CHB) and reducing the risk of
hepatocellular carcinoma (HCC) development. The PLC/PRF/5 cell line is
commonly used as an in vitro model for studying HBV integration. In this
study, we employed a range of multi-omics techniques to gain a panoramic
understanding of the characteristics of HBV integration in PLC/PRF/5
cells. Methods: Transcriptome long-read sequencing (ONT) was
conducted to analyze characterize the transcriptional activity of
different HBV DNA integrations in PLC/PRF/5 cells. Additionally, data
pertaining to epigenetic regulation such as whole-genome bisulfite
sequencing (WGBS), histone chromatin immunoprecipitation sequencing
(ChIP-seq), and assay for transposase-accessible chromatin using
sequencing (ATAC-seq) were collected to investigate the potential
mechanisms associated with the transcriptional regulation of integrated
HBV DNA. Result: Our findings indicate that transcriptional
activity of integrated HBV DNA in PLC/PRF/5 cells is influenced by
methylation levels of the surrounding host genome near the integration
site. The result indicated that elevated methylation of the adjacent
host genome adversely impacts transcription activity of integrated HBV
DNA. Furthermore, we observed a positive association between histone
modification H3K4me3 and the transcription of integrated HBV DNA. These
results suggest that host may regulate transcriptional activity of
integrated HBV DNA through DNA methylation and histone modifications.
Potentially leading to the silencing of integrated HBV DNA.
Conclusion: Our study brought a better understanding on the
transcriptional regulation of integrated HBV DNA. This knowledge can be
valuable in the development of novel strategy for functional cure of
CHB.
Cather-related right atrial thrombosis: a case series and literature review
Authors: Palomera Raul Cruz , Alvarado Juan Francisco Rodríguez , Fonseca Jorge Guillermo Arenas
Published: October 2023

-Background: Complications associated with central venous
catheters, such as right atrial thrombosis, are a common but poorly
recognized complication. Therefore, it is important to describe the
follow-up and the various forms of treatment along with the responses
associated with it; Because if the approach is delayed, this leads to a
higher rate of complications and morbidity and mortality. -Case
presentation: This case series presented three patients with
catheter-related thrombosis. The first patient was a 55-year-old man who
presented with short bowel syndrome requiring the placement of
parenteral nutrition through a central venous catheter, which was
complicated by thrombosis; During the approach he remained stable, so he
was managed with anticoagulation with an adequate response. The second
case was a 56-year-old woman who presented with chronic kidney disease
and started renal replacement therapy with hemodialysis, but it
progressed poorly with the formation of a thrombus in the Mahurkar
catheter, which caused obstruction of the tricuspid valve, so it was
managed with surgical thrombectomy with a favorable development.The
third patient was a 31-year-old man with chronic kidney disease and
renal replacement treatment with hemodialysis that was complicated by
the generation of a thrombus in the Mahurkar catheter, who was
hemodynamically stable, so he was treated only with anticoagulation with
favorable resolution. -Conclusions: Although there is no
standardized treatment in these patients, the approach and management
must be based on the experience of the medical center in addition to the
characteristics related to the patient and the thrombus, associated with
the patient’s hemodynamic status. Therefore, it is important to
highlight in our series the use of various treatments which were adapted
to the characteristics of the cases that finally led to an adequate
clinical evolution.
The Optimum Fins Length Distribution of Tabular PCM Heat Exchanger
Authors: Mussa Munther , Saleh Hussein Hatem
Published: October 2023

The study aims to find the optimal fin length distribution for improved
heat transfer during melting and solidification in a tubular PCM heat
exchanger designed for heat storage. Three types of horizontal PCM
tabular heat exchangers, all with five longitudinal fins, were studied
numerically. While maintaining a constant heat transfer area, each model
depicts a unique fin length distribution design. The first model, which
serves as the reference design, has a homogeneous fin length
distribution and each fin is 30 mm long. The second model has shorter
upper and side fins and longer lower fins (20 mm for the upper fin, 25
mm for the side fins, and 40 mm for the lower fins). The third model has
long lower fins but shorter than that of second model, short side fins
and no change in upper fin length with reference design (30 mm for upper
fin, 25 mm for side fins and 35 mm for lower fins). The findings
indicate that the second model exhibits the best heat transfer
performance for the melting process, while the first model is most
effective for solidification. Interestingly, the third design emerges as
the optimum choice for both melting and solidification processes.
A qualitative study of the relationship between perceived overtreatment risk and seeking medical services through guanxi
Authors: Zhou Kairu , Chen Li
Published: October 2023

Objective: Perceiving overtreatment risk and seeking medical
services through guanxi are prevalent and closely related in China, but
research has failed to explore the combination of the two. This study
analyses the interaction rule and response patterns between perceiving
overtreatment risk and guanxi among public hospital inpatients in China.
Methods: Fifteen inpatients from different clinical departments
were recruited for semi-structured interviews at a public county
hospital in Province A in China from July to October 2021. Qualitative
research methods were used to collate and analyze the data.
Results: According to the data analysis, four themes emerged:
(1) reasons for reasons for seeking medical services through guanxi, (2)
classification of perception of overtreatment risk, (3) the interaction
between guanxi and perception of overtreatment risk, and (4) suggested
solutions. Guanxi is becoming a collective unconscious act for patients.
Age, income, literacy and health insurance policies affect patients’
perceptions of overtreatment risk. In health care, guanxi and perceiving
overtreatment risk interact with each other as causes and effects.
Conclusion: This study analyzes the dialectical relationship
between medical risk perception and relationship with doctors, aiming to
provide a new paradigm for the study of doctor-patient relationship, to
improve the quality of patient-centered healthcare services, and to
provide a framework and ideas for health policy makers and managers to
improve the design of doctor-patient relationship management system.
Moreover, the lack of intervention by health managers between patients’
medical risk perception and relationship to medical care is not
conducive to the establishment of a harmonious doctor-patient
relationship and a good medical environment in the long run. Therefore,
health administrators should do a good job of publicizing science,
calling on patients to correctly view the relationship between patients
and doctors, and strengthening the joint decision-making and trust
between doctors and patients.
Affective Touch is encoded by pupil dilation as a comprehensive social phenomenon
Authors: Bonino Greta , Mazza Alessandro , Capiotto Francesca , Berti Annamaria , Pia Lorenzo , Monte Olga Dal
Published: October 2023

Affective Touch plays a pivotal role in regulating emotions, fostering
social bonds and nurturing affiliations with others. The emotional and
arousing dimensions associated to Affective Touch are linked to the
activation of the CT- fibres system, an afferent pathway attuned to
those specific features of tactile stimulations which characterize
gentle human caresses, such as touch velocity and the nature of the
stroking source. While previous research has examined the physiological
responses in relation to these individual features of Affective Touch,
no study has explored how they interact to shape autonomic activity. In
this study, we investigated whether and how touch velocity (CT-optimal
vs. CT-suboptimal) and the nature of the touching effector (Human hand
vs. Artificial hand) influenced the participants’ pupil dilation and
their subjective experience during tactile stimulation. We observed a
higher pupil dilation when touch was delivered simultaneously at
CT-optimal speed and by a human hand. This kind of touch invoked a
supralinear enhancement of pupil dilation indicating that the
combination of these two features induced a significantly stronger
autonomic activation than the summed effects of each delivered
separately. Moreover, this specific type of touch was perceived as the
most pleasant compared to all other tactile stimulations. Therefore,
pupil dilation appears to map the positive and pleasant experience of
human-to-human tactile interactions. Collectively, our results support
the notion that the autonomic nervous system encodes the emotional and
hedonic aspects associated with Affective Touch as a complex and
holistic social experience, rather than solely responding to its
low-level sensory properties.
No placebo or ergogenic effect of beetroot juice during virtual-reality 20-min cycling time trials: a randomised, balanced placebo design remote study
Authors: Matta Guilherme , Edwards Andrew , Roelands Bart , Hettinga Florentina , Hurst Philip
Published: October 2023

A large body of evidence has shown that placebo effects of dietary
supplements can improve sport performance. However, very few studies are
conducted outside of the laboratory. This is important given that
placebo effects may be more likely to be induced during highly
controlled, artificial environments in the presence of a researcher. In
the past three years, home-based, virtual-reality cycling has increased
in popularity, where over 3-million athletes train or compete against
athletes worldwide. The aim of this study was to examine placebo effects
of an acute dose of beetroot juice during 20-minute cycling virtual
reality time-trials. In line with the CONSORT statement, we used a
between-participant, randomised balanced placebo design, and recruited
67 trained cyclists who performed 3x20-min cycling time-trials
(familiarisation, baseline and experimental) on a virtual-reality
software at home. During experimental trials, participants were
randomised to one of four groups: 1) told beetroot juice/given beetroot
juice, 2) told beetroot juice/given placebo, 3) told placebo/given
beetroot juice, and 4) told placebo/given placebo, who received
nitrate-rich beetroot juice (containing ~552 mg nitrate)
or nitrate-depleted placebo (containing ~0.2 mg
nitrate). Compared to baseline, performance during experimental
time-trials was not different in any of the groups (effect size range:
0.00 to 0.14). Our results, indicate that placebo effects and beetroot
juice do not improve virtual-reality 20-min cycling time-trial
performance. These results have important considerations for future
research to determine the occurrence of placebo effects and
effectiveness of dietary supplements outside of the laboratory.
At Least Nine CMIP6 Climate Models fail the Historical Experiment Test because they do not accurately reproduce the known occurrence of ENSO events and must be withdrawn
Authors: Potts Keith Alan
Published: October 2023

The Historical Experiment (HE) data in the Intergovernmental Panel on
Climate Change (IPCC) Climate Model Intercomparison Project six (CMIP6)
should demonstrate that all submitted models accurately simulate the
climate of the recent past. I show: none of nine models analysed
accurately creates the known occurrence of ENSO events; no model agrees
with any other; and average aerosol levels of the South East Asian Plume
(SEAP), the South AMerican Plume (SAMP) and the West African Plume (WAP)
are too low. Additionally, the SEAP and the SAMP cause the global
temperature to rise in all nine models and the WAP in six models. Hence
these models and all others which cannot accurately portray the known
occurrence of ENSO events should be withdrawn from CMIP6 until they can
and use of the IPCC Assessment Report six (AR6) should be paused until
the effects of these aerosol plumes on the global temperature is
re-evaluated.
Enhancing Small and Medium Enterprise Performance through Supply Chain Integration: A Case Study of Malaysia
Authors: Talib Nurul Azlinda Chek , Abd Razak Noraznira , Mahmud Nurazree
Published: October 2023

This conceptual paper aims to explore the significant impact of Supply Chain Integration (SCI) on the performance of Small and Medium Enterprises (SMEs) in Malaysia. The paper outlines the key elements of SCI, its importance in today's globalized business environment, and how it can be tailored to meet the unique challenges faced by SMEs in the Malaysian context. By analyzing existing literature and incorporating case studies, this paper provides insights into the potential benefits and challenges of implementing SCI strategies for SMEs in Malaysia. Additionally, it suggests recommendations for policymakers, industry practitioners, and academics to further promote SCI adoption among SMEs in Malaysia.
Financial Well-Being of Micro-Entrepreneurs: A Proposed Conceptual Framework
Authors: Mohd Hidzir Putri Aliah , Ismail Shafinar , Syed Nor Sharifah Heryati , Md Sahiq Aqilah Nadiah
Published: October 2023

The financial well-being of micro-entrepreneurs is a multifaceted concept that encompasses both financial stability and personal satisfaction with one's financial situation. The pandemic experienced by the country has affected people from all walks of life, including micro-entrepreneurs. These self-employed people not only scored the lowest when it comes to financial behaviors but they are also the most vulnerable in terms of financial well-being. This study intends to fill a gap in the literature by looking at the factors that influence micro-entrepreneurs' financial well-being in Malaysia. A systematic review of reviews was conducted through electronic databases between January 2018 and December 2022 using refined search methods, such as the Boolean operator, phrase searching, truncation, wild card, and field code functions, based on enriched keywords: ("FINANCIAL WELL-BEING*" OR “FINANCIAL WELLBEING) AND ("MICRO-ENTREPRENEUR* OR “MICRO-ENTERPRISE*"). Scopus and Web of Science were selected as the two primary databases to search for relevant articles and materials for the review. The results demonstrate the incorporation of several variables into the proposed framework of financial well-being of micro-entrepreneurs, namely social trust, social networks, financial self-efficacy, and financial innovation as a mediator. The proposed framework is derived from the Social Capital Theory and the Social Cognitive Theory, as well as reviews of past empirical studies.
WAQF and Tourism Industry Sustainability: Post-Pandemic COVID-19
Authors: Ismail Shafinar , Ismail Mohammed Izzuddin , Mohd Hidzir Putri Aliah , Ismail Suzila
Published: October 2023

This study attempts to address whether waqf fund, social-cultural, or transversal pillars can contribute to tourism industry sustainability after the COVID-19 pandemic for both Malaysia and Indonesia. Questionnaires were distributed online to the employees who work in the tourism industry. The result indicates that the social-cultural pillar should be the focus of Malaysia and Indonesia for the tourism industry's sustainability after the COVID-19 pandemic. The responses obtained reveal that the respondents believed that better local facilities and infrastructure could improve the social-cultural pillar; therefore, it can pull tourists to travel again. This study contributes to the body of knowledge by conforming that the social-cultural pillar is essential for the tourism sector's Sustainability in both countries. This idea benefits the policymakers, the tourism industry itself, and other stakeholders because it provides an improved understanding of the importance of the social-cultural pillar for the Sustainability of the tourism industry. This study offers useful insight into waqf and tourism industry sustainability in the post-pandemic COVID-19 in Malaysia and Indonesia.
Cybersecurity Awareness on Personal Data Protection Using Game-Based Learning
Authors: Abdullah Zamlina binti , Dahlan Nurazian binti Mior , Dahlan Azlin binti , Irfan bin Ahmad Faris , Arifin Ahmad Samsul
Published: October 2023

The increasing digitalization in modern society has many positive effects on communication, business, education, banking, etc. However, it has also made people more vulnerable to a variety of cybersecurity risks. The rise in cyberattacks raises serious concerns about the lack of basic knowledge and awareness regarding cyber threats such as phishing, malware and password attacks. These cyber-threats can become dangerous for users as they can even cause identity theft and loss of money. The problem arises because lack of awareness of cybersecurity on personal data protection, a lack not a good understanding of how to protect the data, and a lack of knowledge to prevent cyber threats. Thus, this project proposes game-based learning to provide awareness and educate especially the youth on cybersecurity and personal data protection in a fun and effective way. The knowledge gained from the game can be applied to reduce the risks of cybercrimes. Agile methodology has been chosen for this project and has five phases which are requirement, design, development, testing, deployment and review. The enjoyment level of the game is evaluated by using an adaptation of the E-Game Flow Model including concentration, goal clarity, feedback, challenge, autonomy, immersion and knowledge improvement. Findings of enjoyment evaluation showed that the game receives an 82% level of agreeability by the game users. The game increases awareness among game users about cybersecurity. Future work for this game includes adding more levels into the game, covering other cyber threats and enhancing mobile devices.
Assessment of Merger Control in the Philippines
Authors:   Asian Development Bank,   Asian Development Bank
Published: October 2023

Analyzing current merger control measures in the Philippines, this report recommends ways to bring its regime fully in line with international best practices to help promote economic competition and spur productivity. A co-publication between ADB and the Organisation for Economic Cooperation and Development (OECD), it reviews merger legislation, examines the application of merger controls, and looks at relevant cases and decisions. Its recommendations include basing merger decisions on technical assessments, establishing clear adjudication procedures, and guaranteeing procedural transparency to strengthen the integrity and fairness of mergers in the Philippines.
Existence and multiplicity for fractional Dirichlet problem with γ(ξ)-Laplacian equation and Nehari manifold
Authors: da C. , Oliveira D.S. , Agarwal Ravi
Published: October 2023

This paper is divided in two parts. In the first part, we prove coercivity
results and minimization of the Euler energy functional. In the second part,
we focus on the existence and multiplicity of a positive solution of
fractional Dirichlet problem involving the ?(?)-Laplacian equation with
non-negative weight functions in H?,?;? ?(?) (?,R) using some variational
techniques and Nehari manifold.
ดัชนีชี้วัดธรรมชาติในเมือง ไอยูซีเอ็น กรอบวิธีการและตัวชี้วัด
Authors:   IUCN, International Union for Conservation of Nature
Published: October 2023

The IUCN Urban Alliance, a broad coalition of IUCN constituents concerned with the urban dimensions of nature conservation, has unveiled a new knowledge product for measuring the ecological performance of cities: the IUCN Urban Nature Indexes (UNI). Comprising six themes with five indicator topics nested within each theme, the UNI is intended to help policymakers, stakeholders and local communities understand their impacts on nature, set science-based targets for improvement, and monitor progress using science-based measures. By enhancing environmental transparency and accountability, and by focusing on improvement rather than fixed targets, the UNI aims to catalyse local action for nature in all cities.
Carica Papaya Root Extract in Management of Urolithiasis
Authors: Shankar Avinash
Published: October 2023

These days urolithiasis is on progressive rise due to increased urinary solute and altered electrolyte biokinetics. In addition change in dietary composite also made the women equally vulnerable for the presentation. Though surgical removal and lithotripsy are measures available for alleviation of uroliths Clinical manifestation, but recurrence is very common posing encumbrance and agonizing discomfort. In present scenario of available various indigenous drug composite, clinical evaluation of Carica papaya root extract 10-25 ml with Piper nigrum 1-3 daily in empty stomach ensure relief of abdominal colic and passage of uroliths per urethra in majority cases with complete absence of uroliths in USG of KUB or in urine and no recurrence on weekly one dose in 2 yrs of post therapy follow up without any adversity
A Randomized Controlled Trial to Study Efficacy of Amavata Pramathini Vati when given with Vaitaran Basti in the Management of Amavata
Authors: Bhairav  B Tawshikar
Published: October 2023

Amavata is particular type of disease that is mentioned in Ayurveda since the period of Madhavkar, under the category of Vata- Kaphaja disorder. According to Ayurveda, Ama is caused due to malfunctioning of the digestive and metabolic mechanism. Vata is the chief functional operator of the all types of voluntary or involuntary movements of body. Vitiated Vata, Dosha along with Ama is termed as Amavata. It indicates the propulsion of Amaby vitiated Vata throughout body getting lodge in Sandhi sthana (jointareas) producing Amavata. Amavata issucha disease of chronic joint pain and bodyache, accompanied by swelling of some or all of the Synovialjoints. Angamarda (Bodypain), Aruchi (Lossoftaste), Trishna (Thirst), Alasya (Lackofenthusiasm), Gourav (heaviness), Klama (Tirednesswithoutdoingwork), Apaka (Indigestion) and Jwar (fever). Amavata can be correlated with Rheumatoid Arthritis. The prevalence of RA increases between 25-55yrs of age. Chakradatta was first to describe in the treatment for Amavata. He gave Basti chikitsa especially Vaitaran Basti is considered as the chief treatment regimen for Amavata and Amavata Pramathini Vati is a formulation which is prescribed to treat Amavata. The description of Amavata Pramathini Vati is found in Bhaishajya Ratnavali. Amavata Pramathini Vati is a formulation off given drugs Kalmishora, Arkamula, Shuddha Gandhaka, Loha Bhasma And Abhrak bhasma. These drugs play significant rolein reducing the symptoms and to treat the Amavata. The drugs have Vata Kaphaghna property which reduce Vata and Kapha, Doshas from the body and reduces the symptoms of Amavata.