bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerapan Perluasan Keputusan Tata Usaha Negara Sebagai Upaya Dalam Penegakan Hukum Administrasi dan Kaitannya Dengan Prinsip-Prinsip Good Governance (Sebagaimana Diatur Dalam Pasal 87 UU No. 30 Tahun 2014 tentang Administrasi Pemerintahan)
Authors: Ahmad Fauzi
Published: April 2023

Lahirnya Undang-Undang Nomor 30 Tahun 2014 tentang Administrasi Pemerintahan menjadikan objek gugatan Peradilan Tata Usaha Negara semakin luas. Salah satunya adanya tindakan faktual yang termasuk ke dalam Keputusan Tata Usaha Negara. Pemberlakuan tindakan faktual menjadikan banyak interpretasi bagi penegak hukum dalam menentukan pelanggaran hukum yang dilakukan pejabat tata usaha negara. Tindakan faktual memberikan interpretasi yang beragam sehingga dapat menimbulkan penyalahgunaan kewenangan sehingga tidak terwujudnya good governance. Paradigma good governance memiliki prinsip akuntabilitas, sehingga segala perbuatan pejabat tata usaha negara dapat dipertanggungjawabkan. Salah satunya pertanggungjawaban di hadapan hukum karena telah mengeluarkan suatu keputusan tata usaha negara. Hal ini dapat mewujudkan tujuan dari good governance tersebut. Good governance selalu melekat dengan ciri negara hukum dan demokratis, segala tindakan pejabat tata usaha negara harus berdasar hukum. Oleh sebab itu, diperlukan peraturan pemerintah untuk memperjelas para penegak hukum dalam menafsirkan tindakan faktual. Pejabat tata usaha negara juga dapat menjalankan tugas sehingga good governance dapat terwujud.
Evaluation of Patient Data Protection in the Implementation of the E-Health Program in the City of Surabaya
Authors: Megawati Suci , Epriliantor Deby Febriyan , Mahdiannur Muhamad Arif , Sidik Rizky Muhammad , Fajar Muhammad Kharis
Published: April 2023

The city of Surabaya has implemented the e-health program since 2014. Protection of patient data is the most important aspect in evaluating e-health health programs. The research objective is to analyze the evaluation of patient personal data protection in e-health programs. The research method uses descriptive qualitative with a case study research strategy. Data collection techniques used a mixed-method approach. The research results show that the protection of patient data in the implementation of the E-Health Program in the city of Surabaya is reviewed from indicators (1). Guarantee of Patient Data Confidentiality service recipient version; (2). E-Health Application Security; (3). Efforts to Convince Users in Using E-Health; (4). E-Health Service Application Security from Irresponsible Parties; (5). Patient Personal Data Guarantee program implementation version.
Preparation and Characterization of a Clay-Based Ceramic Membrane for Tannery Wastewater Treatment
Authors: Muazu Abubakar  , Norhayati Ahmad
Published: April 2023

In this work, a porous clay-based ceramic membrane was developed from locally sourced clay from Nigeria. The clay was ground and sieved through 100 μm size. The chemical, mineralogical, thermal and particle size properties of the clay were determined using XRF, XRD, TGA/DTA and PSD respectively. Starch composition from 10-25 wt% was added to the clay and thoroughly mixed with water. The dough was cast on a potter’s wheel. The produced membranes were fired at a temperature of 900 °C. The maturation properties of the fired clay were determined using bulk density and apparent porosity. Multi-point BET was used to determine the pore characteristics of the membranes. The flexural strength of the produced membrane was determined using a three-point bending test. The microstructure of the fired clay was recorded using FESEM. Membranes produced from the clay were used for the treatment of tannery wastewater. The XRF result shows that the clay contains high silica and alumina. Also, the XRD results show the clay contains many peaks of montmorillonite and other peaks of feldspar and quartz. The BET shows that the pore size of the membranes produced was in the mesoporous range. From water quality test, it shows that the locally sourced clay can be used to produce ceramic membranes for filtration and separation applications.
Structural Elucidation of the Masp1 and Masp2 Protein from Nephila Pilipes Web Via Bioinformatics Approaches
Authors: Anwardi Jamil  , Amirul Ridzuan Abu Bakar  , Nurul Husna Khairuddin
Published: April 2023

Major ampullate spidroin (MaSps) from orb-weaver spp spider has recently gained interest due to its exceptional characteristics. The biomechanical and biochemical properties from MaSps offer potential in harvesting and exploiting MaSps as a promising bio-based product. However, the current research on the structural elucidation focused more onto the Nephila clavipes spider web rather than the Nephila pilipes which are more common in this region. Herein, this study integrates the used of computational power and algorithm to elucidate the 3D protein morphology of MaSp1 and MaSp2 of Nephila pilipes dragline silk protein using nearly complete amino acid sequences obtained from the protein database. In silico homology modelling via Phyre2, SWISS-MODEL and RaptorX was adopted to predict the protein structure of MaSP-1 and 2 using proteins threading, automated comparative modelling of three-dimensional (3D) protein structures and deep learning approaches. Consequently, we described a thorough 3D protein models of MaSp1 and MaSp2 with a higher percentage of coils, α-helix and a low percentage of β-sheet on repetitive regions of MaSp1 and MaSp2. The results of this current work provide insights into Bioinformatics potentials in engineering spider silk-based biomaterial and bridging the most apparent gaps in the knowledge of MaSp1 and MaSp2.
The Cutting Edge of Vibration Energy Harvesting Technology
Authors: Ruzlaini Ghoni  , Mohd Tarmizi Ibrahim  , Nik Fakhri Nek Daud  , Ammar Husaini Hussian  , Shaiful Rizalmee Wahid  , Ahmad Farid Ridhwan Zakaria  , Hamdan Azmi Abdul Aziz
Published: April 2023

Energy harvesting has been around for more than a decade, with continual research tackling the issues of charging and powering up electronic gadgets. Because of its multiple advantages, such as greater mobility and a longer lifespan, the notion of energy harvesting has acquired broad popularity. Researchers are investigating methods to harness the energy created by vibrations from various materials and transducers as part of the energy conservation movement. This paper examines major advancements in vibration energy collecting during the last 15 years. It focuses on the many processes used to collect vibration energy, such as piezoelectric, electromagnetic, electrostatic generators, and MEMs techniques, as well as power management circuits, to enhance various elements of vibration energy harvesting devices from diverse sources. While the research on vibration energy harvesting has grown significantly, this work summarises significant achievements in the subject over the last 15 years and updates prior review publications.
Zero-Biasing Split Ring Resonator using Metamaterial Element for High Gain Superstrates Ultra-Wideband Antenna
Authors: Nur Amirah Othman  , Mohd Aminudin Jamlos  , Wan Azani Wan Mustafa  , Mohd Faizal Jamlos  , Mohamad Nur Khairul Hafizi Rohani  , Syahrul Affandi Saidi  , Hidayath Mirza
Published: April 2023

Complex materials with artificial structures known as metamaterials (MTM) have unique properties that draw several scientists to use them in a variety of research fields. In addition, MTM can go beyond some of the restrictions placed on tools used in technical practise while improving the characteristics of microwaves. The Internet of Things (IoT) application calls for the construction of zero-index Split Ring Resonator (SRR) MTM element superstrates with an ultra-wideband antenna. Keep in mind that the MTM simulates behaviour that is not found in nature, namely the zero-reflection phase (dB) on the resonance frequency. For this project, an antenna with an SRR MTM unit cell operating at 2.70 GHz is built. The SRR has four inductance-related loops (r1, r2, r3, and r4), and gaps (slots) are added to the ring to produce the capacitance effect. Parametric research has been done for the SSR in the interim to identify the best design with zero indexes, permittivity and permeability at the desired frequency. The MTM unit cells array design's 7 x 4 and 10 x 5 dimensions achieved a dB of 0° at the 2.70 GHz frequency range. A 7 x 4 MTM unit cell makes up the first design, MTM Antenna Design 1, which at 2.70 GHz recorded a gain of 5.70 dB and a return loss (S11) of -20.007 dB. The return loss (S11) at a frequency of 2.70 GHz was -19.734 dB in the second design, an MTM antenna consisting of 10 x 5 MTM unit cells, which recorded a gain of 5.66 dB.
The Role of Banking in Reducing Poverty in 30 Indonesian Provinces
Authors: TRIDEWI Afifa Wahyu , ISMAIL Munawar , SUSILO Susilo
Published: April 2023

The line of thought in this research is about the role of banking in its role in reducing poverty in Indonesia. In accordance with Article 4 No. 10 of 1998 concerning banking, that banking supports the implementation of national development in order to increase equity, economic growth, and national stability towards improving people's welfare. The data used in this study is secondary data in the form of panel data from 2000 to 2018, namely savings, credit, GDP, poverty, inflation, and unemployment data. The analytical model used in this study is a multiple regression model of panel data
Analysis of the Influence of Digitalization on UMKM Growth (Case Study of Bangka Belitung and Yogyakarta UMKM)
Authors: ILYAS Rahmat
Published: April 2023

UMKMs in Indonesia have an important role for the Indonesian economy. Currently, UMKM are an alternative to new employment opportunities to reduce the impact of unemployment in Indonesia. In addition, UMKM also play an important role in driving Indonesia's economic growth rate. During the ongoing Covid-19 pandemic occur moment In this case, UMKM activities experience various challenge at a time opportunity for growth Indonesian economy. Experienced challenges _ among them lack of introduction to digitization, adaptation to the development of the digital world and not have potential HR who can enter the digital world. study this is study descriptive quantitative, explained how The effect of digitalization on the growth of UMKM in the provinces of the Bangka Belitung Islands and Yogyakarta. Focus Study this UMKM in the provinces of Bangka Belitung and Yogyakarta Islands. the number of samples in this study 38 9 . The results of the research show that variable knowledge digitization take effect to UMKM growth , seen from t count value 8.131 > 1.967, value significant ie 0.000 < 0.05. variable digitization marketing take effect to see the growth of UMKM from t test results show 2.058 <t- table 1.967 value significance of 0.040 <0.05. Variable digitization sale take effect to UMKM growth with t value 9.100 <1.967, significance of 0.000 <0.05. variable digitization payment take effect to see the growth of UMKM from score t value 5.042 > 1.97 significance of 0.000 <0.05.
The Role of Indigenous Institutions in the Implementation of the Malacca Agricultural Revolution Development Program (RPM) in Umatoos Village, West Malacca District, Malacca Regency
Authors: BRIA Albertus , TAMUNU Lenny M. , SAYRANI Laurensius P.
Published: April 2023

The Malaka Agricultural Revolution Program (RPM) has not optimally involved all elements of the Umatoos Village community, while one of the institutions in the village that is capable of mobilizing the community is a traditional institution through the fukun-fukun (tribe head). This research is qualitative with a phenomenological approach. The location of this research was Umatoos Village, West Malaka District, Malacca Regency with 14 informants. The type of research data is qualitative and quantitative, with primary and secondary data sources. Data collection techniques using observation, interviews. Document searches were analyzed using data analysis techniques from Bungin (2012:70). The role of Indigenous Institutions in the implementation of the Malacca Agricultural Revolution Development Program (RPM) in Umatoos Village, West Malaka District, Malacca Regency was analyzed using the opinion of Mintzberg (1973:51) where there are three roles carried out in the organization with the findings that; (a) the interpersonal role of the Umatoos Village customary institution is not utilized for its role as Figurehead, Leader and Liaison Manager, (b) an informational role where the Umatoos Village customary institution is not utilized for its role as monitor, disminator and rapporteur and (c) the Umatoos Village customary institution is not utilized role as a decisional role. The inhibiting factors for the role of traditional institutions in implementing the development of the Malacca Agricultural Revolution (RPM) in Umatoos Village were; (a) the role of village customary institutions as village partners is not utilized, (b) there is no program/activity design and (c) the lack of resources.
Results of the re-introduction of the Griffon Vulture (Gyps fulvus) in Vrachanski Balkan Nature Park, Bulgaria – completion of the establishing phase 2010–2020
Authors: Stoyanov Georgi , Peshev Hristo , Kmetova–Biro Elena , Stoynov Emilian , Ivanov Ivelin , Vangelova Nadya , Nikolova Zlatka , Mitrevichin Emanuil , Grozdanov Atanas
Published: April 2023

The current study analyses and presents the results of the ten-year establishment phase of the Griffon Vulture (Gyps fulvus) local re-introduction in Vrachanski Balkan Nature Park, north-western Bulgaria. Between 2010 and 2020, 61 rehabilitated and captive-bred Griffon Vultures from Spain, France and several European zoos were released from an acclimatisation aviary. The first successful breeding in the wild was reported in 2015. Thus, the species has been restored as a nesting species in the area after more than 60 years of absence. In 2020, the local population accounted for some 55–70 individuals, consisting of about 20–23 breeding pairs in three-five separate colonies and two frequently-used roosting sites. Forty-two chicks fledged from 2010 to 2020, at an average breeding success of 0.46 chicks/territorial pair and productivity of 0.62 fledglings/breeding pair. The mortality rate is calculated at 0.34; an additional 0.07 of the released individuals have never been seen or found. The local nucleus of the Griffon Vulture now covers a territory of 1,478.58 km², calculated as a 95% home range, while the 50% core area is 9.07 ± 5.73 km2 (range 2.12–22.89 km2). With these results, we consider the establishment phase of the re-introduction of the species in Vrachanski Balkan Nature Park as completed.
Dataset for mosquitoes (Diptera, Culicidae) from State Route 905-Mile Marker 2, Key Largo, Monroe County, Florida, USA
Authors: Boehmler Michael , Murray Heidi , DeMay David , Rogers Adriane , Hribar Lawrence
Published: April 2023

The Florida Keys Mosquito Control District has used dry ice-baited light traps to monitor mosquito populations on Key Largo since 2003. This paper describes the methodology of trapping, the habitat and the dataset of adult mosquito populations from 18 years of weekly monitoring from a single site on Key Largo, Monroe County, FL, USA.

This data paper provides previously unpublished data from a single trapping location in Key Largo, Florida. Two new species have been added to previously-published data from this trapping site.
Une anthropologie des relations
Authors: Lasida Elena
Published: April 2023

La conversion écologique à laquelle nous invite l’encyclique Laudato si’ constitue un véritable changement de paradigme qui place la relation au cœur de l’existence : une invitation à concevoir la relation non pas comme un moyen pour vivre, mais comme la vie elle-même. Ce changement suppose une « dés-instrumentalisation » et une « endogénéisation » de la relation. Cette démarche sera esquissée à l’aide de trois approches qui seront mises en dialogue : celle sous-jacente dans la conversion écologique, celle associée à la valeur économique, et celle véhiculée par la mésologie. En guise de conclusion, l’expérience pratique du label Église verte servira pour illustrer une démarche de conversion écologique fondée dans la dimension relationnelle de la vie.
On some new vector valued sequence spaces $ E(X, \lambda, p) $
Authors: Duyar Osman
Published: April 2023

To define a new sequence space and determine the Köthe-Toeplitz duals of this sequence space, characterizing the matrix transformation classes between the defined sequence spaces and classical sequence spaces has been an important area of work for researchers. Defining and examining a new vector-valued sequence space is also a considerable field of study since it generalizes classical sequence spaces. In this study, new vector-valued sequence spaces $ E(X, \lambda, p) $ are introduced. The Köthe-Toeplitz duals of $ E(X, \lambda, p) $ spaces are identified. Also, necessary and sufficient conditions are determined for $ A = (A_{nk}) $ to belong to the matrix classes $ (E(X, \lambda, p), c(q)) $; where $ A_{ nk}\in B(X, Y) $, $ X\in \{c, \ell_\infty\} $ and $ Y $ is any Banach spaces.
A Breakthrough With Machine Learning in Real-Time Environments
Authors: Gracewell Jeffin
Published: April 2023

Over the past few years, machine learning (ML) has seen potential growth globally and has contributed a huge role in technological advancements. With improved learning mechanisms, the ML algorithms have provided huge breakthroughs and enhancements in solutions for the real-time global challenges that persist. With large amounts of digital data evolving each day, ML algorithms have evolved as the right-to-go approach, to provide technological breaks though by overruling the traditional methods. The chapter aims to briefly review the overview of ML algorithms and highlight the different applications under various segments where ML has contributed to providing breakthrough solutions. The applications that are to be discussed from different segments are healthcare, businesses, government, security, agriculture, industry, and the educational sector. The objective of the chapter is to provide the readers with a better understanding of how ML applications are used in different segments and the advancements it brings to modern technology.
AI for IoT Application
Authors: Pise Ganesh Shivaji , Babar Sachin D.
Published: April 2023

The popularity of the Internet of Things (IoT) has increased due to the development of faster internet networks and more advanced digital devices (Smarter Hardware), such as sensors integrated into a microcontroller. Currently, sensors and other digital devices used in diverse geographical sectors, such as agriculture, hospitals, smart homes, and smart cities, generate and share vast quantities of data. These IoT data must be collected and mined using AI for knowledge management (AI). Collaboration between AI and IoT results in intelligence system automation. This continuum will influence all emerging industries, including healthcare, transportation, manufacturing, and retail. IoT devices generate vast quantities of data, and AI will aid in more intelligent data planning for various IoT applications. In the software engineering and technical research processes, AI techniques are utilized for automatic problem solving and problem identification.
Automation of System Infrastructure Upgrade or Downgrade Using AI
Authors: Jonnalagadda Chiranjeevi Nageswarababu
Published: April 2023

Building recommendation systems and automating their implementation for businesses is the key to a better business environment. It will be helpful to businesses to save on infrastructure costs, get better performance, and upgrade or downgrade systems automatically based on live processing data. The proposed solution is to calculate the upgrade or downgrade of CPU, RAM, disk type, network speed, etc., based on live data of usage automatically. Using cloud platforms or standalone systems and servers, the system infrastructure can be upgraded, downgraded, or customized based on application needs. Using the system alerts, one can get inputs on CPU, RAM, disk usage, network speed, etc. to run automation scripts using AI to achieve the proposed solution. It will be helpful to businesses to save on infrastructure costs, get better.
RezFind
Authors: K. Srikanth , Mishra Dibya Nandan , Pujari Pratyusha , Sravya Pingili , K. Vishal , Chenna Sankalp
Published: April 2023

A typical job posting on any job-hunting portal like Linkedin, Naukri, Indeed, etc., will receive many resumes. Screening a resume manually is a tedious process involving huge costs. Screening resumes also consumes a lot of time for the hiring managers. Sometimes, because of the massive numbers, a few qualified resumes don't get noticed, leading to considerable loss to both the company and a loss of opportunity for the applicant. This study uses advanced natural language processing to automate the resume screening process. It also describes a data mining method to extract relevant information like the eligible applicant's name, contact, and email. RezFind provides a unique scoring system that gives a similarity score between the job description and the resume to keep it very specific to the job posting instead of a generic screening. This process allows keeping the uniqueness of each job role, and the screening quality increases by having a specific job description.
Evaluating Environmental Crimes Through the Prism of Criminological Theories
Authors: Mohanta Abhinash , Sneha  , Muduli Himanshu Sekhar
Published: April 2023

Humans and society are structured on cyclical routines, recurrent happenings, and patterns. Our brains are so wired for this habit that we frequently detect chaotic patterns when none exist. Environmental crimes are no different—we hear about different forms of environmental crimes on a daily basis. Crimes like poaching, wildlife killing, pollution, artificial forest fires, illegal logging, and the list go long. Addressing the topic academically is necessary to know this particular type of crime, and what triggers the perpetrators to commit such offenses. Criminology has always been supportive as a step towards every social science subject. So, in that sense, it's necessary to learn about environmental crimes through the prism of criminological theories. The chapter provides detailed insight with the help of a systematic review of major criminological theories in environmental crimes. The need for the chapter is crucial because before getting into the paradox of addressing and punishing such crimes, it's necessary to address the genesis of such crimes.
Situation of Women and Girls Displaced by the Violence of the Boko Haram Terrorist Group in Nigeria
Authors: Rodríguez María José Jiménez , Mugica Saioa Erro
Published: April 2023

This research aims to analyse the situation in Maiduguri, capital of Borno State, northeastern Nigeria, one of the areas hardest hit by the violence perpetrated by the terrorist group Boko Haram, which has led to the forced displacement of thousands of people who have fled their homes to safer places such as camps for internally displaced persons or refugees. Using a qualitative methodology, within the interpretative paradigm, the aim is to find out whether actions are being developed to promote gender equality and equal opportunities, to analyse the degree of involvement and awareness of the community regarding the importance of gender equality and finally, and how we could contribute from international development cooperation to improve the situation of displaced women. Thanks to the needs assessment carried out in this research, it is possible to detect existing shortcomings and draw conclusions that will serve as a basis for the design of a proposal for social intervention aimed at achieving gender equality through the promotion of women's autonomy in the Maiduguri IDP camp.
The Transformation Framework for Geopolitical Analysis/Middle East's Geopolitical Events
Authors: Trad Antoine Toni
Published: April 2023

This chapter uses the author's applied holistic mathematical model (AHMM) to support geopolitical analysis (GA) activities and decision-making in the context of eXtreme crisis (XC), like the one that has been striking Lebanon for more than five decades. GA needs a polymathic in-depth structure that can be abstracted with a generic GA Concept (GAC). The AHMM for GA (AHMM4GA) was already used to analyze the origins of the destabilization of the Middle East's area (MEA) and especially in the case of the directed wars on Lebanon. This destabilization resulted in extremely violent destruction and immigration of its minorities; especially in the period between the years 1943 and 1982, which was already analyzed by the author and was identified as phases I and II (or LDWPI and LDWPII). In this chapter, the focus is on the period between the years 1982 and 1990 (or LDWPIII), that followed the LDWPII.
Analysis of the Capacity of ChatGPT in Relation to the Educational System of the Dominican Republic
Authors: Bueno Johan Manuel Tapia
Published: April 2023

In recent years, artificial language model technology has advanced remarkably, offering a wide range of applications in various fields, including education. ChatGPT is one of the most advanced artificial language models currently available, and its ability to generate coherent and realistic responses to questions has raised concerns about its impact on the education system. In this article, the capacity of ChatGPT in relation to the education system is analyzed, and the implications of its use in teaching are discussed.
A contribution from Umberto Veronesi Foundation
Authors: Tonelli Chiara
Published: April 2023

Dear Editor,I have read with great interest your Editorial “Science in Ukraine is bleeding”. As a scientist, I strongly feel that researchers should pay both human and scientific attention to the tragedy occurring to Ukrainian scientists, since the Russian invasion [...].
Exploring the Molecular Mechanism of Radix Astragali on Colon Cancer Based on Integrated Pharmacology and Molecular Docking Technique
Authors: Jiang Yong , Chang Yao-Dan , Wang Meng , Sun Yan-Ping , Bi Yu-Jin , Wang Zhi-Bin , Kuang Hai-Xue
Published: April 2023

Objective:

The objective of this study was to study the mechanism of Radix Astragali on colon cancer by integrated pharmacology and molecular docking technique.

Methods:

Integrative pharmacology-based research platform of traditional Chinese medicine (TCMIP) V2.0 was used to obtain the chemical components and corresponding targets of Radix Astragali and the target information of colon cancer to create the main target network of drugs and diseases. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis was carried out using Hiplot website, and the interaction network of “Traditional Chinese Medicine-component-target-pathway” was established, and molecular docking with main targets was carried out for the key components.

Results:

Twenty-seven chemical constituents of Radix Astragali, their 254 corresponding targets, and 44 colon cancer-related targets were obtained. Through proteins interacting, 70 nodes were obtained as core targets. GO analysis showed that it mainly acts on lipid metabolism, nuclear receptor activity, phagocytic cup, etc. KEGG pathway analysis showed that it was mainly enriched in the estrogen signaling pathway, C-type lectin receptor signaling pathway, PI3K-Akt signaling pathway, etc. The multidimensional network, quantitative estimate of the drug, and molecular docking showed that the main targets are AKT1, BCL2, and CDK6, and the key components involved are kumatakenin, astragaloside VIII, and choline.

Conclusion:

Kumatakenin, Astragaloside VIII, Choline and other compounds of Radix Astragali may affect colon cancer by acting on AKT1, BCL2 and other targets, thereby regulating estrogen signaling pathway, C-type lectin receptor signaling pathway, PI3K-Akt signaling pathway and so on. Those will provide theoretical reference for future research on the material basis and mechanism of its pharmacodynamics.
A Study of Acute Kidney Injury in COVID-19
Authors: Narayanashetty Satyanarayana , Bellary Vaibhav S. , Rajanna Avinash H. , Rao Nishkala U
Published: April 2023

Background:

Severe acute respiratory syndrome-coronavirus-2 responsible for the pandemic of COVID-19 has been one of the biggest challenges faced by humankind. The virus predominantly affects the respiratory system. However, the continued study of the disease since the beginning of this pandemic has evolved our understanding of COVID-19 which showed varied presentations with multisystem involvement, leading to acute myocardial infarction, stroke, pulmonary embolism due to its prothrombotic nature as well as acute kidney injury (AKI).

Objectives:

(1) To determine the incidence of AKI in COVID-19 (2) To correlate AKI with the outcome of the COVID-19 patients.

Materials and Methods:

The present study involves 200 patients who were suffering from COVID-19 admitted to a hospital in Bengaluru during the period of June 2020–May 2021, fulfilling the inclusion criteria were analyzed and appropriate data were collected after obtaining informed consent.

Results:

Majority of the subjects belonged to >50 years of age group. Among the recruited subjects, 117 (58.5%) were male and 83 (41.5%) were female, 170 patients were discharged and 30 patients died. The mean urea levels were 37.82 ± 23.68 mg/dl and mean creatinine values were 0.95 ± 0.85 mg/dl. The urea levels among the COVID-19 patients who were discharged was 35.98 ± 20.27 mg/dl and among those who died was 52.22 ± 38.01 mg/dl, respectively, and this was statistically significant (P = 0.00). The creatinine levels were 0.88 ± 0.44 mg/dl and 1.32 ± 1.76 mg/dl among the COVID-19 patients who got discharged and expired, respectively, and this too was statistically significant (P = 0.00).

Conclusion:

The patients suffering from COVID-19 who had developed AKI at the time of presentation had a poor prognosis as well as increased risk of mortality.
Occurrence and Risk Factors for Acute Kidney Injury in Patients Hospitalized with Acute Pyelonephritis, and their Clinical Outcomes: A Single Center Study from Northern India
Authors: Seth Saksham , Bhat Nucksheeeba Aziz , Sheikh Rayees Yousuf , Keshwani Puja , Mehta Pranav
Published: April 2023

Background:

Acute kidney injury (AKI) associated with acute pyelonephritis (APN) is considered rare. This study is conducted to find out the occurrence and risk factors for AKI in patients hospitalized with acute pyelonephritis and their clinical outcomes.

Materials and Methods:

All inpatients with APN from December 2018 to May 2020 were included.

Results:

A total of 95 patients were included. Escherichia
coli was the most common organism grown. At presentation, 79/95 (83.2%) patients had renal dysfunction. 31/79 (39.2%) patients required hemodialysis. AKI was 2.4 times common in men; P = 0.013. The mean duration of fever in patients with and without renal dysfunction was 8.30 ± 2.72 and 5.31 ± 0.91 days, respectively; P < 0.001. 73/79 (92.4%) patients with AKI had anemia as against 2/14 (14.2%) patients without AKI; P < 0.001. AKI developed in 100% of the patients with known chronic kidney disease (CKD) at baseline and 41.6% of the patients with normal baseline kidney function; P < 0.001. Diabetes mellitus was present in 29/79 (36.7%) patients with AKI and 6/16 (37.5%) patients without AKI; P = 0.31. Hospital stay in days was 11.65 ± 5.9 and 5.81 ± 0.91, respectively, in patients with and without renal dysfunction; P < 0.001. 6/95 (6.3%) patients died. All six patients had renal dysfunction. At 3 months, renal functions normalized in 38/79 (48.1%) patients and 8/31 (25.8%) patients remained dialysis-dependent.

Conclusions:

AKI is a common complication of APN. It is usually reversible with early and appropriate management. Male gender, anemia, bilateral pyelonephritis, baseline CKD, and delayed presentation to hospital are associated with increased risk of AKI. It is associated with an increased risk of dialysis, hospitalization days, and mortality.
A Retrospective Observational Study of Presentation, Diagnosis, and Management of Patients with Genitourinary Tuberculosis in a Tertiary Care Hospital of India
Authors: Krishna Vivek , Mylarappa Prasad , Rathnakar Surag Kajoor , Janna Rakesh K. , Priyatam K.
Published: April 2023

Objectives:

To study the clinical features, diagnostic methods, and management of genitourinary tuberculosis (GUTB).

Methods:

This retrospective study included 117 patients with GUTB admitted over a period of 10 years. The analysis of the patients was done in terms of presentation, organ involved, diagnostic methods, and management. The 6-month anti-tubercular treatment (ATT) was given to all patients, which included isoniazid, rifampicin, and ethambutol/pyrazinamide. Follow-up period was 1–10 years.

Results:

The mean age of the patients was 32.5 ± 6.4 years with a male: female ratio of 1:1.51. The majority of the patients presented with irritative voiding symptoms (66.47%) and hematuria (47.6%). The common infected organs were kidney (64.9%), ureter (27.35%), urinary bladder (17.09%), prostate (3.4%), and epididymis (5.19%). 25.6% of patients had positive chest X-ray, and 61.2% of the patients had positive Mantoux test. The diagnostic positivity rate for polymerase chain reaction, urine Mycobacterium
tuberculosis culture test, and urine acid-fast bacilli test was 67.7%, 35.4%, and 21.6%, respectively. 71 (60.13%) of the patients needed surgical intervention. After medical therapy, the adverse reactions noted were abnormal liver function in four cases, pruritus in three cases, and skin eruption in one case. Among the total of 117 patients followed over a period of 1 year to 10 years, none recurred.

Conclusion:

In a retrospective study of 117 patients with GUTB, majority had bladder symptoms, 60.13% needed surgery, and all were treated with 6-month course of ATT regimen consisting of isoniazid, rifampicin, and ethambutol/pyrazinamide, with none showing recurrence during the period of 1–10 years of follow-up.
In-Patient Morbidity and Mortality Patterns among Patients with Diabetes in Southwest Nigeria: A Multicenter Prospective Study
Authors: Olamoyegun Michael A. , Ala Oluwabukola A. , Ojo Olubukola A. , Akinlade Akinyele T. , Ajani Gbadebo D. , Enikuomehin Christianah A.
Published: April 2023

Background:

Diabetes is a disease of public concern with increasing hospital admissions and mortality in developing countries. Hence, we aimed to determine the patterns of in-hospital morbidity and mortality in patients admitted for diabetes.

Methods:

A prospective multicenter analysis of the causes of hospital admission and death among patients with type 2 diabetes who were admitted from diabetic clinic and emergency units over a 3-month period in selected tertiary hospitals in southwest, Nigeria was conducted. Data analysis was performed using the SPSS version 21.0.

Results:

A total of 341 patients with diabetes were admitted with a mean age of 59.6 ± 15.6 years and overall mortality of 14 deaths (4.4%). Almost three-fifths (59.5%) were previously known patients with diabetes with a mean duration of 52.44 ± 30.02 months. Two hundred and thirty-one (70.9%) patients were admitted through the emergency units and others through outpatient clinics. The duration of hospital stay ranged from 1 to 135 days, with a mean duration of 24.5 ± 14.7 days. The diabetes-related indications for admission were hyperglycemic crisis (diabetes ketoacidosis [DKA] and hyperglycemic hyperosmolar state [HHS]) (59.8%), diabetic foot ulcer [DFU], (11.7%), hypoglycemia (7.6%), and infections (7.3%). Among the diabetes-related diagnoses, 100%, 77.8%, 50.0%, 41.7%, and 28.3% of patients with chronic kidney disease, stroke, DFU, DKA, and HHS respectively stayed longer than 10 days on admission.

Conclusion:

Diabetes still contributes high cause of morbidity in our hospitals but with a reduced mortality compared to previously reported figure. Hence, continued emphasis on early diagnosis with improvements in diabetes care will help to improve diabetes outcomes.
A Comparative Study of Bacteriological Profile and Outcomes in Infective Exacerbation of Chronic Obstructive Pulmonary Disease and Bronchial Asthma
Authors: Nagaraja B. S. , Chandrashekar Arjun P. , Menon Anindita
Published: April 2023

Background:

According to the Global Burden of Disease 2018, chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, and in India, COPD is the second leading cause of death among noncommunicable diseases. Among India’s 1.31 billion people, about 6% of children and 2% of adults have bronchial asthma. Infective exacerbations of both COPD and Bronchial asthma are common. However, there are some differences in the bacterial spectra between the two conditions, and profiling the bacteria responsible for the exacerbations will help in choosing appropriate antibiotics and also to combat the issue of drug resistance.

Aims:

(1) To analyze the bacteriological profile of patients with infective exacerbation of COPD and bronchial asthma. (2) To study the outcomes among these patients.

Subjects and Methods:

The study was a prospective observational study conducted from November 2019 to May 2020 in Bangalore Medical College and Research Institute on 50 patients diagnosed with acute exacerbation of COPD and 50 patients diagnosed with an exacerbation of bronchial asthma. Detailed history, physical examination, and standard laboratory tests were done on admission. Sputum samples were collected from the patients and analyzed by Gram staining and microscopy and also by culture. The differences between the two groups were analyzed. The progression of the disease and the outcomes were observed.

Results:

100 patients were included in our study, 50 each in COPD and bronchial asthma. The study was conducted in hospitals attached to BMCRI. Bacteriological profile was assessed by sputum culture and antibiotic sensitivity in the COPD and asthma groups, respectively. In our study, in the COPD group, majority (80%) of patients were males, the mean age was 64.34 ± 9.876, and 80% were smokers with 20% having exposure to biomass. The most common growth in COPD exacerbation was Streptococcus pneumoniae (18%) followed by Haemophilus influenzae and Klebsiella pneumoniae. Mortality in COPD exacerbation was 12%. In the asthma group, female preponderance was seen (54%), mean age was 40.64 ± 13.11. Majority of patients were cases of childhood asthma. Growth was seen in 32% of exacerbations and the most common organism was Streptococcus pneumoniae. Mortality was 4% and importantly due to comorbidities.

Conclusions:

Bacterial exacerbations are more common in COPD, while it is not so in bronchial asthma. Viral exacerbations and atypical bacterial exacerbations are more common and asthma associated with pneumonia is the cause for culture growth. Mortality is considerably low in the asthma group compared to COPD exacerbations.
On Being a Physician to Celebrities!
Authors: Naik Sadananda B.
Published: April 2023

It is rewarding but often very challenging to be the physician to a celebrity and there are many virtues as well as shortcomings in this position of importance. This is a short write-up on what it takes to be a doctor to a celebrity.
Epidemiological Features of Healthcare-associated Acinetobacter baumannii Infections in Taiwan During 2008 − 2019
Authors: Hsieh Chi-Jeng , Yu Chia-Peng , Liang Chun-Yu , Liao Min-Tser , Liu Li-Chun , Lin Fu-Huang
Published: April 2023

Background:

Acinetobacter baumannii can reside in humans without causing infection or symptoms but can opportunistically cause community and nosocomial infections. Few studies from Taiwan have used national-level data to investigate antibiotic resistance rates of A. baumannii infections in the intensive care units (ICUs) of medical centers.

Aim:

This study determined the number of infection sites of A. baumannii and the resistance rates of carbapenem-resistant A. baumannii (CRAB) infections in ICUs in Taiwan, and identified trends over time, variations of infection site, and factors associated with resistance.

Methods:

This study used the database provided by Taiwan's Centers for Disease Control. Yearly, Taiwan Nosocomial Infections Surveillance System Surveys from 2008 to 2019 were analyzed, including data on the site of infection and resistance rates of A. baumannii and patient and hospital characteristics.

Results:

On average, 21 hospitals as medical center/year participated in the survey, and 6803 A. baumannii isolates were identified. All isolates were health care-related infections. The most frequent sites of infection were the urinary tract (50.6%), respiratory tract (19.6%), bloodstream (18.2%), surgical wounds (4.3%), and others (7.4%). Infection rates were the highest in the urinary tract in 2019 (63.6%; P < 0.001). On average, the rate of carbapenem resistance was 66.6% (95% confidence interval: 63.1–70.1) among ICU patients at medical centers. Considerable regional differences were observed, with the highest rates of resistance in the central regions. Higher resistance rates were observed between 2019 and 2020 COVID-19 pandemic (74.2%).

Conclusion:

This is the first report on the prevalence of health care-related A. baumannii infection in Taiwan in 2008–2019. Several invasive diseases, such as urinary tract infections, are associated with higher rates of carbapenem resistance. The resistance rate of CRAB in Taiwan is exceptionally high. The current big-data-derived findings may inform future surveillance and research efforts in Taiwan.
Acute Cardiopulmonary Decompensation Following Ethanol Sclerotherapy under General Anesthesia
Authors: Chen Yen-Chu , Lai Hou-Chuan , Huang Yi-Hsuan
Published: April 2023

Ethanol sclerotherapy is a therapeutic method commonly applied to address low-flow vascular malformations. However, numerous complications, including hemodynamic instability, may develop after ethanol injection. We present a case who experienced cardiopulmonary instability during intraoperative percutaneous ethanol injection under general anesthesia and spontaneously recovered 5 min after ethanol injection. The toxic effects of the treatment were associated with the injection volume and may be related to ethanol-induced pulmonary vasoconstriction and transient right ventricular dysfunction. Prompt and proper management, including providing supportive treatment, decreasing pulmonary vascular resistance with pulmonary vasodilators, and improving right ventricular function, should be carefully prepared to minimize the progression of cardiovascular collapse.
Optimization of New Energy Vehicle Road Noise Problem Based on Finite Element Analysis Method
Authors: Mao Fujun
Published: April 2023

In the use of new energy vehicles, user experience has always been the key project of major manufacturers. At present, the research on user experience focuses on the posture performance of the vehicle itself, and less attention is paid to road noise. Therefore, this study takes the road noise problem of new energy vehicles as the object. The finite element analysis method is chosen for modeling. And the research on the optimization of road noise is carried out. After modeling, the correctness of the model was tested, and all four modes were controlled within the modal error range of 5%. When the new energy vehicle based on this model ran at 80 km/h, the peak road noise was reduced by about 11 dB(A). In addition, after optimizing the tire, the peak value decreased by 4 dB(A). After optimizing the transverse stinger of the rear suspension, the Z-bending mode was increased by 22.3 Hz. Compared with the previous basic scheme, the optimization effect was obvious. When the optimized new energy vehicle ran at a speed of 60 km/h, the peak value is reduced by about 5 dB(A) on the rough road with a frequency of 65 Hz. The results showed that, under the proposed method, the road noise problem was improved, the peak value of the problem was eliminated, and the expected acceptable range was reached.
Prevalência da mutação causadora da Paralisia Periódica Hipercalêmica em equinos da raça Quarto de milha na região centro norte do Paraná
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Silva Leticia Canali da , Mafra Gustavo Fernandes ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Pires Amanda Marcondes ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Faccio Alice Ribeiro ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Greco Henrique Moretti ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Romani Isaac ,   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil.
Published: April 2023

A Paralisia Periódica Hipercalêmica (HYPP) é uma doença causada pela mutação no gene SCN4A resultando em fraqueza muscular, contrações involuntárias e hipercalemia, podendo levar a óbito. O objetivo do estudo foi avaliar a prevalência da mutação causadora da HYPP na região centro norte do Paraná em equinos QM das modalidades de laço e três tambores. Após a coleta de pelo da cauda de 52 animais, as amostras foram encaminhadas para extração, quantificação, amplificação por primers específicos do gene SCN4A e sequenciamento em laboratório terceirizado. Os resultados revelaram que nenhum dos animais apresentou a mutação causadora do HYPP.
Atividades Lúdicas: uma experiência do Programa Criança Feliz
Authors:   Centro Universitário Ingá – Uningá, Maringá, PR, Brasil., Borges Giovanna Solcia
Published: April 2023

Este trabalho é resultado da atividade proposta do PIESC II-Atividades Lúdicas no Desenvolvimento das Potencialidades Humanas proposto pela Uningá, foi desenvolvida no CRAS-Centro de Referência de Assistência Social de Alvorada do Sul-PR, em atividades propostas através do Programa Criança Feliz um Programa do Governo Federal, que atende gestantes e crianças de 0 a 3 anos, com média de 80 famílias, conta com 4 visitadores. O trabalho é desenvolvido através de visitas domiciliares e contatos via WhatsApp para contato e retorno das atividades propostas.
Formation of marketing environment in agro-industrial complex
Authors:   Kazakh Research Institute of Economy of Agro-Industrial Complex and Rural Development, Rustembayev B. E. , Abdigul G. K. ,   S. Seifullin Kazakh Agro Technical University, Amangeldiyeva Zh. A. ,   L.N. Gumilyov Eurasian National University
Published: April 2023

One of the main directions of development of the country's economy is the domestic agro-industrial complex. Currently, agricultural industry faces many problems, including high depreciation of its fixed assets, lack of production resources and shortage of qualified personnel, since most of them are concentrated in households, which in turn reduces the level of economic activity and product quality. The goal is to study economic mechanism of functioning of the marketing environment to improve the efficiency of functioning of enterprises in agricultural sector. The article discusses the features of marketing services in the field of agro-industrial production. The object of the study is the agriculture of the Akmola region of Kazakhstan. Methods – statistical analysis using sectoral information from official statistics and publications in scientific literature, secondary information, commodity policy technologies. Result – internal and external factors influencing the organization of marketing activities of the Akmola region in sectors of the AIC, trends in potential demand, sales volume, competitive advantages are analyzed, appropriate proposals are prepared. Conclusions – at the regional level, information is provided on consumer preferences, strengths and weaknesses of competitors, forecasting changes in market conditions. The marketing approach is the process of creating a product, determining the price, marketing and promotion strategies. In modern conditions of the need to expand the capabilities of the agricultural economy on the background of lack of financial resources for agro-industrial production entities, in order to increase competitiveness, their own marketing programs should be developed and implemented. The most important, in the opinion of the authors, at the present time are the provision of information and consulting support to commodity producers, as well as attracting investment in agricultural sector.