bluuebunny/crossref_metadata_2025 huggingface dataset:
PARENT COMMUNITY AS SUBJECT OF FORMATION OF PRESCHOOLERS' HEALTH SAVING PRACTICES
Authors: Antonova N L
Published: June 2022

This paper has presented a sociological research conducted in Yekaterinburg in 2012. Objects of that research were parents and their preschool children. The results have shown that there were some problems with formation of children’s health saving practices: disturbances in daily routine, balanced nutrition and domination of passive leisure. Children's community reproduces only sanitary standards. The solution is to develop a single health saving space, which includes children, parents and preschool educational institutions, and to form a new system of interaction between them.
SACRED ECOLOGY AND TRADITIONAL KNOWLEDGE OF PEOPLES OF THE NORTH (PROBLEM STATEMENT)
Authors: Terebikhin N M
Published: June 2022

The article has presented an analysis of foreign and national philosophical-scientific and religious-mythological origins of formation of a subject-problem field of sacred ecology as one of the directions of modern ecological discourse. The author has developed his theoretical model of sacred ecology unfolding the system of interrelations between religion (cult), ethnicity (ethnic mentality), nature carcass and society’s culture. Sacred ecology as the most general knowledge about Home (micro- and macrocosm) is a special synthetic form of traditional knowledge and ceremonial practices. The conceptual results of the author’s long-term research in the field of sacred geography and ecology of the European Russian North indigenous peoples (Nenets and Saami) have been represented.
ECOLOGO-PHYSIOLOGICAL CHARACTERISTICS OF CARBOHYDRATE-LIPID METABOLISM AND THYROID STATUS IN SCHOOLCHILDREN LIVING IN NORTHERN REGION
Authors: Kozlova L A
Published: June 2022

High body mass and obesity are of interest as a medical and social problem of the XXI century. Already at school age, many children have high body mass and obesity, one can state metabolic abnormalities in the serum lipids, carbohydrates, thyroid status. In the study, there have been examined 112 schoolchildren-nonresidents living in the Khanty-Mansiysk Autonomous Okrug: 44 - with high body mass and obesity, 68 - with normal body mass. In the group of the persons with high body mass and obesity, there have been determined reliably higher indices of general cholesterol, low-density lipoproteins, triglycerides (TG), glucose, glycohemoglobin and thyreotrophin and reliably lower indices of high-density lipoproteins and T3. There has been observed a positive correlation between glucose concentration and content of glycohemoglobin in blood (r = 0.983, p = 0.000), general cholesterol (r = 0.455, p = 0.002), triglycerides (r = 0.389, p = 0.034), free thyroxin (r = 0.314, p = 0.038). The level of glycohemoglobin correlated with the content of general cholesterol (r = 0.477, p = 0.001), triglycerides (r = 0.381, p = 0.038). The schoolchildren with high body mass and obesity had higher indices of carbohydrate-lipid metabolism and the thyroid status compared to the control group, what could cause a cascade of metabolic pathological states in young adult life period in the future.
SPIRITUAL-MORAL RESOUCES OF MENTAL MEDICINE
Authors: Sidorov P I
Published: June 2022

In the article, there have been considered the conceptual-methodological approaches to assessment of spiritual-moral components of a set of mind and mental health, mental medicine and preventology; directions of institutionalization and tasks of service and system monitoring of mental health; instruments and technologies of mental medicine making it a strategic scientific paradigm; the spiritual-moral typology of personality and syndromology of animogenesis; diagnostic evolution of synergetic inversion in mental medicine; the need to develop a united corpus of ethics codes of the system of community service (physicians and educators, social workers and priests) and introduction of the innovative complex blockmodular ethical program into high school educational work.
ONE-WAY ANALYSIS OF VARIANCE (ANOVA) IN STATA SOFTWARE
Authors: Unguryanu T N , Grjibovski A M
Published: June 2022

In the article, we have presented theoretical principles of one-way analysis of variance (ANOVA) for comparisons of three or more independent groups. Examples of the use of ANOVA with manual calculations using formulas have been given as well as algorithms of the use of ANOVA in STATA software. Special consideration has been given to the assumptions which have to be tested as well as the ways to present the results in research papers.
ENVIRONMENTAL SITUATION AND TRACE ELEMENT STATUS OF CHILDREN AGED 1-3 YEARS IN UNURBANIZED TERRITORY OF RUSSIAN EUROPEAN NORTH
Authors: Bakaeva E A , Eremeyshvili A V
Published: June 2022

With the use of the method of inverse voltammetry, we have analyzed some specific features of trace element status of children aged 1-3 years in Troitsko-Pechorsk of the Komi Republic taking into account the content of these elements in the environment (drinking water, snow cover). It has been found that the permissible content of zinc was observed in biosubstrates of 40 % of the examined children, copper - in 15 %, lead - in 20 %, and cadmium - in 65 %. The detected changes in the trace elements exchange in the examined children serve as a basis for formation of different diseases.
MENTAL ECOLOGY OF SOCIAL MIND
Authors: Sidorov P I
Published: June 2022

In the article on the basis of the synergetic bio-psycho-socio-spiritual methodology of mental ecology and mental medicine, there has been considered the design of virtual images and narrative meanings through the example of the modern English serial “Sherlock”. There have been described the phenomenology and mechanisms of realization of pathoplastic factors of mental ecology of the Anglo-Saxon world personified in the figure of the central character and accumulating urgent characteristics of social mind and mental health, social and personality identity. There has been grounded the necessity of adaptive development of social mind and introduction of mental health system monitoring allowing to assess effectiveness of mechanisms of morality interiorization and its translation to the level of individual morals.
PSYCHOMOTOR REACTIONS OF SERVICEMEN OF UNCONVENTIONAL UNITS IN PROGRESS OF SERVICE AND COMBAT MISSIONS
Authors: Beskaravayny E B , Gudkov A B , Belozerov S P , Beskaravaynaya A V
Published: June 2022

Individual psychomotor reactions in servicemen of special forces in the dynamics of performance of their service and combat missions have been studied. The data on personality psychological properties and functional processes in the nervous system of the servicemen in reference to different service length has been presented. The study has found that the reliability coefficient in the samples tended to decrease, but at all the studied stages, it was statistically significantly higher in the more experienced servicemen. There have been analyzed the most important parameters of responses to visual stimuli.
DISTRIBUTION OF SOMATOTYPES AND TIME OF SEXUAL DEVELOPMENT OF YOUNG PEOPLE IN URBAN AND RURAL AREAS OF ALTAI REGION
Authors: Filatova O V
Published: June 2022

The antropometric and body composition examination of 500 healthy young people (17-21 years old) - residents of Barnaul and the Altai Territory countryside has been performed. Differences in physical status of the Altai Territory young people depending on residence in urban or rural areas have been detected, they were manifested in a bigger body length, weight, girth of chest, hip circumference, leg length of the city dwellers. A somatotypological analysis has revealed predominance of a normosthenic somatotype among the examined persons. Young men living in the rural areas had a more andromorphous constitution, more timely tempo of sexual development. The results will constitute a basis of the formed Altai regional database.
MAXILLOFACIAL TRAUMA IN CHILDREN
Authors: Bragina V G , Gorbatova L N
Published: June 2022

In the review, we have examined the issues of maxillofacial traumatism in children and adolescents both in Russia and abroad. It has been noted that domestic researchers did not pay sufficient attention to this issue, although the problem of traumatism is still urgent. Special attention in prevention of maxillofacial injuries in children should be given to social factors.
MENTAL ETHNIC ECOLOGY OF HYSTERIC DEMONIC DISORDERS
Authors: Sidorov P I , Medvedeva V V , Davydov A N
Published: June 2022

Etiopathogenetic basis of social and mental epidemies is constituted by bio-psycho-socio-spiritual factors predetermining ways of appearance and mechanisms of development of mass induced nervous-mental disorders which early forms were given the name «hysteric demonic disorders»: shamanistic disease, “mannarik”, arctic hystery, singultation, “sheva”, “lishinka”, “kila” etc. There have been separated clinical forms and pathogenesis of induced states and diseases, factors and forms of traditional intellectual culture influencing social epidemies development features.
LIPID PROFILE IN MEN OF KOMI AND YAKUT ETHNIC GROUPS WITH OVERWEIGHT AND OBESITY
Authors: Lyudinina A Yu , Potolitsyna N N , Solonin Yu G , Osadchuk L V , Gutorova N V , Petrova P G , Troev I P , Ostobunaev V V , Boyko E R
Published: June 2022

A comparative study of lipid metabolism in 152 men representing two populations of indigenous residents of the Russian North - Komi and Yakut - with normal and overweight or obesity has been carried out. There were detected differences in their lipid profiles. The men from the Yakut ethnic group with the body mass index (BMI) 18.4 < BMI < 25 kg/m 2 had higher concentrations of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C) and low levels of high density lipoprotein cholesterol (HDL-C) (p < 0.001), what indicated a more atherogenic background in comparison with the Komi group. The study of lipid metabolism in subjects of different ethnic groups with BMI > 25 kg/m 2 showed a similar picture. Higher percentage of palmitoleic acid in the total pool of lipids was observed in the Yakut men compared to that in the Komi volunteers, and the level of the palmitoleic acid correlated with BMI in the men of both ethnic groups (p
DESCRIPTION OF RISK FACTORS OF NON-INFECTIOUS MORBIDITY AMONG POPULATION OF SURGUT CITY
Authors: Loginov S I , Tretyak A S , Hodosova D A , Umarov E D , Batraeva M V
Published: June 2022

The objective was to study behavioral risk factors of non-infectious diseases, such as physical activity (PA), smoking, food, use of alcoholic beverages in case of a sampled unity of permanent Surgut-dwellers. 2 256 people have been interrogated in an ecological-sociological research by means of telephone interviews. 2 000 people’s samples were processed - 1 000 men and 1 000 women of five age categories: 18 29 years, 30-39 years, 40-49 years, 50-59 and older than 60. Dependence (F = 50.274; p < 0.001) between the indicators of health and PA of the respondents, between PA and presence of children in a family (F = 45.549; p < 0.001) has been revealed. The PA level depends on education (F = 17.130; p < 0.001) and profession (F = 60.273; p = 0.012). Dependences between PA and a marital status (F = 1.128; p = 0.288) have not been revealed. Gender distinctions have not been revealed in PA (F = 2.903; p = 0.313), between PA and heart insufficiency (F = 1.376; p = 0.241), ischemic illness (F = 0.554; p = 0.457), smoking (F = 2.239; p = 0.265), myocardial infarction (F = 4.249; p = 0.047).
EPIDEMIOLOGY OF COMMUNITY-ACQUIRED PNEUMONIA IN ARKHANGELSK
Authors: Bedilo N V , Vorobyova N A , Ismaylova N V , Veshchagina N A
Published: June 2022

A retrospective analysis of 411 medical records of patients with diagnosed community-acquired pneumonia and treated in an in-patient department in 2010-201 1 has been carried out. Morbidity and mortality data in the Arkangelsk region have been also analyzed. It has been found that the incidence rate and hospital mortality in our region were at the national level and the mortality rate exceeded that. The patients with community-acquired pneumonia were predominantly persons older than 45 years. The proportion of severe community-acquired pneumonia in the hospital was 27 %. Chronic alcoholism accompanied 57 % of the severe pneumonia cases.
ENDOPROTHESIS REPLACEMENT OF HIP AND KNEE JOINTS: EPIDEMIOLOGICAL ASPECTS AND EFFECT ON QUALITY OF LIFE
Authors: Borisov D B , Kirov M Yu
Published: June 2022

Total hip and knee replacements are effective surgical interventions which eliminate pain and improve functions in patients with end-stage degeneration of the hip or knee joints. In this article, we have considered epidemiology of hip and knee replacement, projects for demand of arthroplasties in the future, changes in health-related quality of life and factors that influence long-term results after surgery.
HUMAN PROTEIN BLOOD COUNT DISORDERS UNDER IMPACT OF AROMATIC HYDROCARBONS
Authors: Zaytseva N V , Zemlyanova M A , Tarantin A V
Published: June 2022

The review considers the influence of the most common aromatic hydrocarbons (benzene, toluene, styrene, xylene) polluting the environment and being a risk factor for various health disorders, including metabolic changes in the protein profile of the human body.
AROMATIC AMINO ACIDS METABOLISM IN HUMANS EXPOSED TO EXPERIMENTAL SEVERE ACUTE SHORT-TERM NORMOBARIC HYPOXIA
Authors: Chernykh A A
Published: June 2022

In aviation, acute hypoxia is one of the most dangerous factors affecting humans, and developing new ways of increasing human hypoxic resistance in severe acute hypoxia remains important. In this work we have studied particular features of proteinogenous aromatic amino acids metabolism in volunteers breathing hypoxic gas mixture containing 9 % of O 2. We have shown that the healthy volunteers exposed to experimental hypoxia in postprandial state significantly decreased plasma levels of free tyrosine and phenylalanine in the early recovery period. We hypothesized that these amino acids being precursors for mediators and hormones (dopamine, epinephrine, norepinephrine) can play a significant role in increasing hypoxic resistance in humans.
MOBBING SYNDROME: MENTAL ECOLOGY OF DESTRUCTIVE PROFESSIOGENESIS
Authors: Sidorov P I
Published: June 2022

Mobbing has entered reference books as the syndrome including harassment and insult of employees in the workplaces for the purpose of constraint for dismissal. In the framework of the synergetic methodology, fractal dynamics of mobbing sociogenesis, psychogenesis and somatogenesis have been separated. Approaches to early diagnostics and prevention in the framework of the strategies of adaptive professiogenesis formation have been explained. A system approach to development of preventive-correctional and treatment-rehabilitation medico-psychosocial programs has been proposed.
MONITORING OF CONGENITAL MAXILLOFACIAL DEVELOPMENTAL ANOMALIES IN CONDITIONS OF ADVERSE EFFECT OF ENVIRONMENTAL FACTORS
Authors: Tekutskaya E E , Gusaruk L R
Published: June 2022

An ecological-population monitoring of congenital maxillofacial developmental anomalies (lip and palate cleft) through the example of the Krasnodar Territory with use of medical documentation, data of demographic statistics and ecological examinations according to the geoecological card of the Northern Caucasus and the Medical-ecological atlas of the Krasnodar Territory has been carried out. A method of the environment ecological state estimation considering quantitative values of polluting emissions from stationary sources in the atmospheric air, harmful substances as a part of sewage dumped in open reservoirs, territorial pesticide loadings on soil has been used. Lead (II) content in biological media of the parents of the children with congenital developmental anomalies has been estimated, it amounted to: in blood serum - from 0.102 to 0.365 mg/dm 3; in saliva - from 0.220 to 0.380; in gastric secretion - from 0.180 to 0.273; in urine - from 0.110 to 0.300; in hepatic exudate - from 0.232 to 0.300 mg/dm 3. In blood of 60 % of the examined mothers and in 45 % of the children with congenital developmental anomalies, cadmium (II) content was 0.005 ± 0.001 mg/l. For the districts of the Krasnodar Territory, a statistical analysis of connections between the indicators of environmental contamination and frequencies of birth of children with congenital maxillofacial developmental anomalies has been made.
CHARACTERISTIC OF ATMOSPHERIC SUSPENSIONS COMPOSITION IN STATE RESERVE “BASTAK”
Authors: Golokhvast K S , Revutskaya I L , Lonkina E S , Pamirskiy I E , Gulkov A N , Khristoforova N K
Published: June 2022

The paper has presented the first results of a microscopic examination of suspended air nano- and microparticles contained in snow of the Federal State Budgetary Institution «State Nature Reserve “Bastak”», Jewish Autonomous Oblast, Far East Federl Area, in winter 2011-2012. In the natural protection zone, different man-made particles have been found.
DYNAMICS OF PULMONARY VENTILATION INDICATORS IN ANNUAL CYCLE IN CHILDREN OF PRIMARY SCHOOL AGE, RESIDENTS OF THE EUROPEAN NORTH
Authors: Smolina V S
Published: June 2022

During a year (in winter, spring, summer and autumn) the spirographic survey of one and the same group of healthy children (33 boys and 32 girls of primary school age, natives of the Arkhangelsk) was conducted. It has been detected that the increased utmost and reserve functional abilities of external respiration in children aged 8-9 years in the transition period from the warm season to the cold season (autumn) are observed. The increased minute pulmonary ventilation in the surveyed children is connected mostly with the increased respiratory volume rather than with respiration rate.
HEALTHCARE-ASSOCIATED AND COMMUNITY-ACQUIRED DIARRHEA IN ARKHANGELSK REGION
Authors: Krieger E A , Samodova O V , Titova L V , Gordienko T A
Published: June 2022

Introduction. Diarrheal diseases remain one of the leading causes of community-acquired infections. In Russia, their role in healthcare-associated infections is poorly understood. The study aimed to analyze incidence and prevalence of diarrheal diseases in children living in the Arkhangelsk region and those in Russia. Methods. The incidence of community-acquired diarrhea (CAD) and healthcare-associated diarrhea (HAD) in Russia and in the Arkhangelsk region presented by Rospotrebnadzor between 2000 and 2011 has been studied. Repeated point-prevalence surveys were performed to assess prevalence of HAI in the Arkhangelsk Regional Pediatric Hospital from 2006 to 2011. Results. The incidence of CAD in the Arkhangelsk region was revealed to be 1.2 times higher than that in Russia. More than the half of the patients were children. On the average, up to 50% of diarrhea cases were of unknown etiology. Prevalence of HAD in the Regional Pediatric Hospital varied between 0.5% and 2.8%. Diarrhea was one of the most common healthcare-associated infections. Conclusions. Diarrheal diseases remain to be a serious public health problem in Russia due to their high incidence among children and laboratory shortcoming.
TRENDS OF SUICIDE MORTALITY IN ADOLESCENCE AND ITS RELATIONSHIP WITH ALCOHOL CONSUMPTION IN MURMANSK REGION
Authors: Shelygin K V , Zenin E N , Bulancev I G
Published: June 2022

The dynamics of suicide mortality in adolescence and its relationship with the level of alcohol consumption in the Murmansk region have been analyzed. The method of autoregression and integrated moving average (ARIMA) was used. The alcohol attributiveness of the male population mortality has been revealed.
FORMATION OF PATIENT RIGHTS PROTECTION SYSTEMS IN FOREIGN COUNTRIES
Authors: Tsyganova O A , Svetlichnaya T G
Published: June 2022

In the article, a comparative analysis of the patient rights protection practice pattern in the developed countries has been presented. 8 national and 38 foreign literary sources have been analyzed. It has been detected that the system of patient rights protection in foreign countries was more often presented by three components: a patient rights commissioner acting apart from state agencies; professional ethical committees; collegiate authorities for medical activities control. In establishing of patient-oriented healthcare, a significant part is played by professional medical and patients· public organizations.
FEATURES OF UROGENITAL CHLAMYDIOSIS AND MYCOPLASMOSIS PREVALENCE IN MILITARY PERSONNEL
Authors: Gubernitskaya S V
Published: June 2022

The paper presents an analysis of the results of a medical and sociological cross-sectional study of urogenital tract pathogens prevalence (Mycoplasma genitalium, Ureaplasma urealyticum and Chlamydia trachomatis) among sailors. A survey of 676 anonymous seamen aged 18-55 years and laboratory testing of clinical samples (first morning urine portion) with the use of the method of polymerase chain reaction in real time have been done. The causative agents of urogenital infections were detected in 18.3 % of the seamen: Ureaplasma urealyticum - in 10.7 %, Mycoplasma genitalium - in 3.8 %, Chlamydia trachomatis - in 3.1 %, mixed infection - in 0.7 %. Prevalence of Ureaplasma urealyticum и Chlamydia trachomatis in the military men was lower and that of Mycoplasma genitalium infection was higher than among the population of Russia and the developed countries of the world.
COMPARATIVE STUDY OF THE UTERINE TUBES SMOOTH MUSCLE MORPHOPHYSIOLOGICAL ORGANIZATION IN ECTOPIC PREGNANCY AND IN HEALTHY NONPREGNANT WOMEN
Authors: Zashikhin A L , Istomina N G , Agafonov Yu V , Baranov A N
Published: June 2022

Smooth muscle cells (SMC) of the human uterine tube isthmus have been studied in two groups — healthy nonpregnant women who underwent surgical sterilization and patients with ectopic (ampullar) pregnancies. The method of target cell dissociation was used. An analysis was performed using the methods of morphometry and quantitative histochemistry (including the analysis of nuclear DNA content, and cytoplasmic protein content). Three types of myocytes with different structural-metabolic parameters have been revealed. The comparative analysis of intact and affected SM of the tubal isthmus demonstrated changes in the structure of leiomyocytes population, optic density of cytoplasmic protein and proliferative activity of myocytes.
ANALYSIS OF INTERNATIONAL LEGISLATION REGULATING PATIENTS’ RIGHTS PROTECTION
Authors: Tsyganova O A , Svetlichnaya T G , Trofimov V V
Published: June 2022

A comparative analysis of the international legal acts for protection of patients’ rights from the period of the system’s formation (mid-20th century) until the present time has been presented in the article. Characteristics of international and the European declarations, charters, guidelines that served the regulatory basis for the development of national legislations for patients’ rights have been given.
CHEMICAL POISONINGS IN ARKHANGELSK CHILDREN AND ADOLESCENTS AND MAIN WAYS OF THEIR PREVENTION
Authors: Varakina Zh L , Vyazmin A M , Sannikov A L , Golenishcheva T V , Plaksin V A
Published: June 2022

There have been considered the main tendencies of chemical poisonings in children and adolescents of the City of Arkhangelsk according to sex, age, kind of toxic agents. All the sex-age characteristics of the reasons and circumstances of poisonings have been analyzed: the boys were mostly exposed to voluntary poisonings with alcohol and its substitutes, the girls — to accidental poisonings (mainly with medicaments). The main ways of prevention of acute poisonings among children and adolescents in the region have been proposed.
BEHAVIORAL RISK FACTORS OF BRONCHOPULMONARY PATHOLOGY IN KOLA NORTH MINERS
Authors: Syurin S A , Rocheva I I
Published: June 2022

The effect of adverse behavioral factors on development of chronic bronchopulmonary diseases (CBPD) has been studied in 841 workers engaged in the underground mining of coppernickel ore. The study has shown that the most pronounced negative impact was caused by smoking. It manifested itself both in a decrease in the number of healthy individuals and in an increased risk of chronic bronchitis and chronic obstructive pulmonary disease progress. Excessive alcohol consumption, physical inactivity and obesity did not significantly affect the CBPD risk. However when combined with smoking, they heightened its negative pneumotropic action. It has been concluded that early detection and management of modifiable CBPD non-productive risk factors were an effective way to improve respiratory health of the Kola North miners.
CLERKSHIP’S OCCUPATIONAL STRESS EVALUATION RELIABILITY
Authors: Bukhtiyarov I V , Rubtsov M Yu , Chesalin P V
Published: June 2022

During a hygienic, psychological and physiological complex study, objective interrelationships between modern office workers work intensity and psychological, as well as the cardio-vascular and the central nervous system functional state changes, have been established. These changes indicated occupational stress development against mental work intensity increase. A complex of methods (including computer programs of psychological tests) for occupational stress manifestations detection at the prenosological stage and prevention have been selected.
EXPERIENCE OF ANTICOAGULANT CLINIC’S WORK IN ARKHANGELSK
Authors: Rogozina A S , Vorobyova N A
Published: June 2022

It is known that use of indirect anticoagulants (IAC) is the main method of treatment and prevention of thrombosis and thromboembolism in patients. Bleeding is the most important and dangerous complication of treatment with indirect anticoagulants. The incidence of bleeding during treatment IAC is 0.9 to 2.7 %, fatal bleeding constitutes 0.07 to 0.7 %, and hemorrhagic strokes account for 2 % of all bleeding. Therefore, the aim of our study was to evaluate quality of therapy with indirect anticoagulants of patients observed in the Northern Branch of the Hematology Research Center (HRC) in Arkhangelsk. According to the results of our study, frequency of hemorrhagic complications (GC) against long-term treatment of NAC was 7.8 % (95 % CI: 7.8 - 9.4) (n = 94), fatal bleeding as a hemorrhagic stroke constituted 0.1 % during 2.5 years of observation. The number of patients who achieved therapeutic hypocoagulation exceeded 60 % (n = 721). Such factors as taking Cordarone (p = 0.019), use of generic coumadin Russia (p = 0.05), ambulatory monitoring of the international normalized ratio (INR) (p = 0.028) as well as dosages of NAC influenced hemorrhage progression statistically significantly, the main factors reflected in bleeding and level of anticoagulation (INR less than 1.6) were the dose of NAC (p = 0.004) as well as control of the INR (p = 0.001). Taking into account the main factors influencing the level of anticoagulation, it is possible to reduce the number of bleeding cases and prediction of NAC doses. This approach will improve commitment to the NAC therapy of different specialists and enhance quality of patients’ life.
MODERN PROBLEMS OF PERIODIC MEDICAL EXAMINATIONS HOLDING AND ASSESSMENT OF HEALTH OF WORKING POPULATION ACCORDING TO EXAMINATION RESULTS
Authors: Prokopenko L V , Sokolova L A
Published: June 2022

Periodic medical examinations (PME) of working population exposed to impact of harmful and dangerous factors of working environment do not provide timely detection of occupational pathologies, what results in progress of persistent loss of occupational capacity in the period of occupational activities. Among the reasons of the situation, there is absence of lists of persons subjected to PME, data on working conditions for assessment of antecedent risk of occupational disease progress, as well as approved methods for assessment of their health indicators according to PME results and establishment of cause-effect relations of disease progress with working conditions. The study of the results of PME of population working in the Arkhangelsk industrial complex has allowed to determine indicators of PME completeness, quality, to calculate medical-biological health indicators for examined contingents, to establish cause-effect relations between disease progress and working conditions.
UROLITHIASIS PREVALENCE IN ULYANOVSK REGION, RISK FACTORS, EARLY DIAGNOSTICS
Authors: Klochkov V V , Ermolaeva S V , Klochkov A V , Kurashov A V
Published: June 2022

The water indicators: mineralization, rigidity, chromatic-ity are risk factors in urolithiasis formation. Potable water with excessive mineralization, rigidity, chromaticity should be exposed to cleaning and filtration in order to prevent formation of stones in the kidneys. In areas with a high risk of urolithiasis, it is necessary to examine population with use of the “Litos-sistema”. That allows to carry out early diagnostics, effective preventive maintenance and urolithiasis treatment.
THE CORRELATION OF HEART RATE VARIABILITY DYNAMICS AND ELECTROCARDIOGRAM DISPERSION MAPPING IN HUMANS BY LONG-TERM MONITORING IN RESTING STATE
Authors: Zenchenko T A , Poskotinova L V , Medvedeva A A , Khorseva N I
Published: June 2022

The monitoring of performance of dispersive electrocardiogram mapping and heart rate variability in 30 healthy volunteers aged from 18 to 59 years in a state of rest was done. It was found that micro-amplitude variations of elec trocardiogram have periodic characteristics, and these fluctuations are largely determined by changes in the balance of the autonomic nervous system. Increased electrical and ion-metabolic instability of right atrium is associated with increased heart rate variability and its vagal component, and the level of micro-amplitude fluctuations variation of velocity characteristics of the initial ventricular depolarization front -with the weakening of parasympathetic activity.
CONDITION OF NONSPECIFIC ADAPTABLE REACTIONS OF THE ORGANISM AND HEALTH LEVELS AT VARIOUS MODES OF EXTREME CRYOGENIC TRAININGS
Authors: Agajanyan N A , Bykov A T , Medalieva R KH
Published: June 2022

Influence of various modes of repeated extreme general air cryogenic trainings at t = —110±5 °С on the levels of health determined by types of nonspecific adaptable reactions and a condition of reactance, is studied. The parallel group analysis with the fixed dose (only 10 sessions lasting 2,5-3 minutes) and a choice of investigated out of almost healthy persons and patients with initial stages of diseases in remission stage on the basis of requirements to a method of open stratification randomization was carried out. The received results show possibility of positive modulation of types of the adaptive reactions, being nonspecific basis of higher levels of health, practically at all three modes of cryogenic influences. Gender features of influence of extreme cryogenic trainings on the states of health (health, intermediate state, illness) are revealed determined by types of adaptive reactions of an organism and corresponding levels of reactance that it is necessary to consider when choosing a procedure mode.
IMPROVING THE MEDICAL ACTIVITY OF PARENTS OF CHILDREN WITH SERIOUS DISEASES
Authors: Svetlichnaya T G , Larionova N S
Published: June 2022

This article presents the results of a qualitative study using focus-group discussion to collect data and content analysis of the information of the answers of informants as an analytical tool to identify the main causes of poor health activity of parents of children with serious diseases and to develop the main directions of its improvement. 18 women aged 30-55 years, parents and close relatives of children with serious diseases, medical and social workers took place in discussion. Focus group discussion revealed a social and professional policies of all representatives, allowed to come to a consensus about a common reason for the low medical activity of parents of children with serious diseases and to suggest ways to improve it.
EFFECTIVENESS OF EDUCATIONAL PROGRAM “THE SCHOOL OF WEIGHT CORRECTION” IN WOMEN, ARKHANGELSK
Authors: Postoeva A V , Bakhtina Z E , Dvoryashina I V
Published: June 2022

The aim of the study was to assess the effect of the educational program “The School of Weight Correction”. Methods. The panel study has been done and included women who participated in the program “The School of Weight Correction” from the 1 st of January till the 31 st of July, 2010 with subsequent observation during six months. We analyzed anthropometric and laboratory data before and after six months. Results. After 6 months there were estimated the reduction of body mass (-11.32 kg , 95 % CI: -9.24; -13.4), body mass index (-2.74 kg/m 2; 95 % CI: -0.69; -6.18), waist (-9.76 cm; 95 % CI: -7.13; -12.39) and hip (-12.66 cm; 95 % CI: -6.28; -19.04) circumferences, mass (-5.86 kg; 95 % CI: -0.11; -11.84) and volume (-4.69 %; 95 % CI: -3.3; -6.08) of fat tissue, systolic (-12.97 mm Hg; 95 % CI: -4.18; -21.76) and diastolic (-9.55 mm Hg; 95 % CI: -5.68; -13.41) blood pressure, and total cholesterol (-1.1 mmol/l; 95 % CI: -0.63; -1.57). Greater basal waist circumference, longer disease duration and greater basal level of total cholesterol were significantly associated with the better waist circumference reduction. Initial body mass (OR = 1.16; 95 % CI: 1.02; 1.33), smoking habits (OR for ex-smokers = 0.17; 95 % CI: 0.04; 0.8); OR for current smokers = 0.05; 95 % CI: 0.00; 0.7) significantly influenced refusals of follow-ups. Conclusions. ”The School of Weight Correction” was effective in reduction of body mass, waist and hip circumference, blood pressure and level of total cholesterol after 6 months.
GENETIC POLYMORPHYSM IN THE GENE OF METHYLTETRAHYDROFOLATREDUCTAZA AND ITS IMPACT ON PLASMA HOMOCYSTEINE LEVEL AND ON LONG-TERM EFFECTS OF ACUTE MYOCARDIAL INFARCTION
Authors: Mukhina P N , Vorobyova N A , Belyakova I V
Published: June 2022

Hipergomocystenemia (HHC) is a significant risk factor for cardiovascular deseases. According to research in HHC incidence of acute myocardial infarction (AMI) increases by 3-4 times. There are hereditary and acquired causes of HHC. One of the reasons is the presence of inherited genetic polymorphisms in the MTHFR gene. According to research conducted by us, the level of homocysteine (HC) plasma at the time of admission was higher than the reference values in 75 % of cases (95 % CI: 60-86). On the 14th day of flow above the AMI level of HC reference values was observed in 73 % (95 % CI: 57-84) cases. The level of HC in patients with homozygous MTHFR gene polymorphism was significantly higher than in patients with heterozygous polymorphism, or without it on the first day of flow of AMI (p = 0.028), and on the 14th day course of acute myocardial infarction (p = 0.001.) In assessment of the long-term outcome after coronary flow AMI endpoints (development of re-infarction, unstable angina, stroke, repeat revascularization, death from CHD), there has been established a clear correlation between the presence of genetic polymorphisms in the MTHFR gene and the development of re-infarction (p = 0.04), the need to repeat revascularization (p = 0.003), the development of unstable angina (p = 0.001). In patients with homozygous polymorphism in the gene encoding MTHFR, re-infarction occurred more frequently (p = 0.021). These data suggest HHC, as one of the most important risk factors for AMI, as well as a higher level of HHC and more severe course of acute myocardial infarction in patients with the presence of polymorphisms in the MTHFR gene.
KNEE JOINT OSTEOARTHROSIS: PROBLEMS AND SOCIAL SIGNIFICANCE
Authors: Matveev R P , Bragina S V
Published: June 2022

This review highlights the social and epidemiological features of osteoarthrosis, with an emphasis on gonarthrosis. It shows the problems of this pathology in the pathogenic, diagnostic, therapeutic and social terms. The social significance of osteoarthrosis is determined by growth of associated invalidity and disability, especially in older age groups, as well as by a sharp decrease of quality of life in this disease. Disability in elderly patients with knee arthrosis is comparable to that of patients suffering from the cardiovascular diseases, and higher than in other diseases in this cohort of patients. Gonarthrosis reduced quality of life of up to 80 % of patients, and disability was diagnosed in 10-21 % of the cases. Timely and effective treatment for osteoarthrosis has enormous social and economic significance.
MECHANISMS OF RESPIRATORY FUNCTION CHANGES AS RESULT OF AUTUMN AND WINTER AIR TEMPERATURE FALL
Authors: Shishkin G S , Ustyuzhaninova N V
Published: June 2022

In the study, there have been examined the mechanisms of external respiration changes in 20 healthy young men living in Western Siberia during an autumn and winter air temperature fall. Spirography and measuring of the lung volumes were performed in a warm room and after a 30 minutes stay in the open air in natural conditions, when the air temperature was from 0 ° to -30 °C at different times. It has been discovered that under the inspiratory air temperature fall, the tidal volumes also decreased. That raised dilution of the inspiratory air in warm alveolar gas and stabilized temperature in the lungs respiratory regions. At the same time, a decrease in the tidal volume led to a decrease in minute ventilation and alveolar oxygen partial pressure in the alveoli. The latter was compensated by an increase in the lung respiratory regions airiness, which increased ventilation efficiency and the lung diffusion capacity. Therefore, the homeostatic respiratory function and thermoregulation were coordinated.
LEVEL OF REGIONAL SOCIAL AND ECONOMIC DEVELOPMENT AND LABOR SAFETY INDICATORS IN MURMANSK REGION
Authors: Karnachev I P , Nikanov A N , Koklyanov E B
Published: June 2022

Calculation of incompletely produced gross regional product in case of a fatal occupational accident in the Northwestern Federal District (NFD) has been done. The territorial indicators were high in the Vologda region and the Komi Republic. Eight NFD regions of ten including the Murmansk region are in the group of high and better-than-average levels of social and economic conditions’s opportuneness for occupational safety.
RISK FACTORS AND REGIONAL CAUSES OF URINARY SYSTEM DISEASES IN CHILDREN IN PRIMORYE
Authors: Luchaninova Valentina Nikolaevna , Ni A , Pogodaeva T V , Bykova O G , Koval'chuk V K , Semeshina O V , Luchaninova V N , Nee A , Pogodaeva T V , Bykova O G , Kovalchuk V K , Semeshina O V
Published: June 2022

Prevalence, dynamics, and regional causes of the urinary tract diseases in children in the Primorsky Krai have been studied. We used epidemiological, hygienic, clinical and statistical methods. The paper has given the results of the analysis of the urinary system incidence in the children in the Primorye Territory in 1998 - 2010. It has been found that the kidney incidence in the children was characterized by an expressed increase. Designed unfavorable prognosis: in next five years, frequency of the urinary tract infections is expected to increase by 3 times in children, by 2 times - in adolescents, and the chronic renal failure-by 2.5 times. Causes of development of the kidney disease are: high frequency of congenital malformations of the urinary system, poor anthropotechnogenic situation and climatic conditions in some areas, inadequate and poor nutrition, mild low-mineralized water supply systems with deficiency of many nutrients. Knowledge of objective data on the incidence allowed to make grounded management decisions regarding implementation of the scientific program for formation of groups at risk and early diagnostics of the urinary system diseases in the Primorye Territory with use of prognostic evaluation tables for neonatal screening.
INNOVATIVE ENVIRONMENTAL AND EPIDEMIOLOGIC TECHNOLOGIES OF ASSESSMENT OF DIOXINS IMPACTS ON CHILDRENS HEALTH
Authors: Revich Boris Aleksandrovich , Sergeev O V , Shelepchikov A A , Revich B A , Sergeyev O V , Shelepchikov A A
Published: June 2022

The town of Chapaevsk in the Samara region remained one of the most notorious hotspots of dioxin pollution in Russia for many years. The levels of dioxins and other persistent organic pollutants (POPs) content in blood and breast milk of the town residents have been monitored since 2003. A longitudinal study of effects of dioxin pollution on physical and sexual development of boys has also begun in 2003. Levels of dioxins and POPs content in blood were measured annually in a cohort of 516 boys. This study documented a relationship between the POP levels in blood and the distance between the residence of the subjects and the source of the dioxin pollution. The POP content levels in blood were higher for the children who received breast milk (TEQ2005 = 24.5; 95 % CI 20.5 - 28.6) than for the children who received artificial feeding (TEQ2005 = 19.1; 16.5 - 22.1). The lower levels of dioxins and PCBs content were observed in the blood of the boys with higher BMI. The higher levels of POPs content in blood were observed among the boys whose families had vegetable gardens (TEQ2005 = 24.5; 23.6 - 27.3) compared to those whose families did not have gardens (TEQ2005 = 20.6;
18.9 - 22.4). The researchers observed correlations between the indicators of the boys physical development and the levels of dioxins and PCB content in their organisms. The levels of POPs content in the blood of the boys varied greatly from very low to very high, but the median levels were considerably higher than those observed in Europe and the USA.
CORRECTION OF DISORDERS OF PSYCHOPHYSIOLOGICAL FUNCTIONS IN SPECIALISTS OF HAZARDOUS OCCUPATIONS BY WAY OF ASSOCIATED USE OF VARIOUS MODAL FACTORS
Authors: Starostin О А , Soloviev А G , Barachevsky Yu Е , Musaev R B
Published: June 2022

48 specialists of hazardous occupations rehabilitated in connection with progress of psychogenic nonpathologic neurotic manifestations have been examined. In the main group (28 men), combinations of physical factors (thermal procedures, vibromassage, aromatherapy, colorrhythmther-apy, music therapy) were used. The total number of daily 25-35-minute sessions was 12-14. In the comparison group (20 men), traditional physiotherapeutic procedures were administered. The rehabilitation period was of the same length in both groups, but the total length of used physiotherapeutic procedures in the comparison group was three times as much. It has been established that for persons with signs of psychogenic nonpathologic neurotic manifestations, different disorders of psychophysiological mechanisms were characteristic. Administration of correction programs with use of combinations of physical factors was accompanied by high speed and accuracy of senso-motor reactions (р = 0.002), sensor systems’ lability (р = 0.037), improvement of nervous processes balance (р = 0.011), physical actions co-ordination (р = 0.006).
CONCEPTUAL APPROACH TO ASSESSMENT OF EXPERTS’ FUNCTIONAL STATUS IN THEIR PROFESSIONAL ACTIVITY
Authors: Maslov N B , Bloschinsky I A , Galushkina E A , Rogovanov D Y
Published: June 2022

Based on systematic analysis of published data and our own data, there has been worked out and introduced a concept of neurophysiological processes that developed during fatigue, over-fatigue of experts in their professional activities. The concept serves as an objective base for dynamic assessment and prediction of the experts’ functional status and health. It has been shown and proved that transition from fatigue to over-fatigue reduced protective inhibition, the effect of "disinhibition" developed, and as a consequence, speed and mobility of nervous processes increased. Volatility and differentiation inhibition increased. With further intensification of over-fatigue, the earlier formed neurophysiological changes were strengthened. Later they were joined by an equalizing phase, and then by a paradoxical phase as initial manifestations of protective inhibition. Asthenic-neurotic states were clinically diagnosed.
PERCEPTION OF GROUP AND ORIENTATION TO INTERACTION OF STUDENTS OF MEDICAL HIGHER EDUCATIONAL INSTITUTION AT INITIAL TRAINING STAGE
Authors: Zashikhina V V , Goldobina Т А , Tsyganok Т V , Pashchenko V P , Lebedev А V , Yushmanova L S
Published: June 2022

Types of orientation to interaction and kinds of perception of a group in second-year students of a medical higher educational institution have been studied. It has been established that the type of perception of the group was mostly affected by the education level, the kind of orientation to interaction was affected by education success. Among the students, there prevailed the pragmatic type of perception of the group; at the Faculty of Dentistry, most students had dominating individualistic motivations. The collectivistic type of perception of the group was characteristic of the low-successful students. Orientation to a task prevailed in the students with medical and non-medical vocational secondary education.
MODERN MODELS OF RISK STRATIFICATION OF CARDIAC OPERATIONS
Authors: Shonbin A N , Bystrov D Olegovich , Zavolojin A S , Duberman B L , Elizarov M V , Yarkovoy M A
Published: June 2022

To provide more accurate stratification models, one should systematically review the figures. In 2010, there was a re-organized multicenter study team of researchers from Papworh Hospital (Cambridge, UK). The project EuroScore II involved 154 centers from 43 countries. One of three Russian centers participating in the project was the Department of Cardiac Surgery of the City Hospital N 1 named after E. E. Volosevitch, Arkhangelsk. Purpose. Participation in a multicenter study EuroScore II for development of modern models of risk stratification of cardiac operations. Methods. There were examined 113 patients over 18 y.o. operated in May-June 2010. Complicated (nonlethal) postoperative period in patients who underwent myocardial revascularization, was observed in 19.5 % of cases, heart valves replacement / repair - in 21.1 %, the combined procedure - in 45.5 %, ascending aorta and aortic arch replacement / repair - in 0 % of cases respectively. Predicted hospital mortality among the patients who underwent myocardial revascularization was 3.7 %, heart valves replacement / repair - 5.3 %, the combined procedure - 18.2 %, ascending aorta and aortic arch repair - 100 % respectively. Conclusions. Use of scale EuroScore I may become less relevant, because there is an expansion of indications for cardiac surgery, due to improved surgical techniques, anesthesia and technical equipment provision. Scale EuroScore II may allow better assessment of cardiac surgery risk.
URGENT PROBLEMS OF CONGENITAL HEART DISEASES IN ADULTS. LITERATURE REVIEW
Authors: Maltseva E V , Martyushov S I
Published: June 2022

In the literature review, there have been considered issues of organization of medical aid to patients over 18 years old with congenital heart diseases, peculiarities of the disease natural course, quality of life, gestation course and delivery, social aspects, rehabilitation of the patients. According to the data from published scientific papers, articles and monographs, concerning the problems of adults’ congenital heart diseases, a conclusion has been made that possibilities of rehabilitation of adult patients with congenital heart diseases and as consequence improvement of quality and increased expectation of life remain not enough studied, in spite of high achievements of modern medicine in this sphere.
DYNAMICS OF CARDIAC RHYTHM VEGETATIVE REGULATION INDICES IN TRAWLER FLEET FISHERMEN IN ARCTIC FISHERY
Authors: Khugaeva S Grigor'evna , Boyko I M , Marunyak S V , Mosyagin I G
Published: June 2022

In our research, 81 fishermen have been examined in order to study the dynamics of physiological characteristics during the 6-month voyage in the Arctic winter climatic conditions on one of the ships of the Arkhangelsk Trawler Fleet. It has been detected that ship work professional experience growth led to increased impact of the sympathetic vegetative nervous system on cardiac rhythm. The dynamics of indices describing the vegetative nervous system functional state concerning the cardiac rhythm depended significantly on the age of the fishermen and the voyage period.