bluuebunny/crossref_metadata_2025 huggingface dataset:
Autism Spectrum Conditions (ASC)-Inclusion: an intervention tool for children with autism spectrum disorders (ASD)
Authors: Mougia Vassiliki , Antareli Theodora
Published: December 2019

It is estimated that 5 million people in the EU countries (1% of the population) are in the autism spectrum. ASC-Inclusion is a new tool that has been studied, designed and constantly evolving from a multidisciplinary team of prestigious Universities and Organizations in Europe. It is an online platform that helps children with autism disorders and their carers. The results of its use are particularly important since there is a significant improvement in the socialization of children with autism disorders, improved adaptive behavior at home and at school, improved emotional expression and emotional recognition. Its further development and implementation is expected to have major social and economic repercussions.
Antibiotics overuse and development of antimicrobial resistance
Authors: Elesnitsalis George , Vekil Ioanna
Published: December 2019

Introduction: The increase in the consumption of antibiotics is becoming a significant problem of recent years in Greece. This study focuses in the necessity of antimicrobial stewardship programs in order to reduce antibiotics misuse.
The purpose of this study was to investigate the excessive antibiotics use and the development of antimicrobial resistance, while spotting measures of antibiotic misuse reduction through the implementation of various protocols by health professionals.
Method: A systematic literature review of research articles was performed, using the electronic database Pubmed and search engine Google Scholar. The inclusion criteria were English language, the research methodology, the specific time that the study was conducted (2007-2017). Five hundred and forty-two articles were found and finally 36 research studies were included in the present systematic review covering all of the inclusion criteria.
Results: Mortality in patients with resistant infectious loads is twice as high as patients infected with non-resistant microorganisms. Prolonged hospitalization increases the risk of developing antibiotic resistance. Applying empirical therapy is often ineffective on colonized patients with multidrug resistant bacteria.
Conclusion: The developement of antimicrobial resistance seems to be a constant threat for public health, leading to morbidity and mortality increase. Designing and implementing new and better practices is the most effective way for combating the problem. Continuous search for new solutions, combined with communication strategies between all stakeholders could contribute to a proper use of antibiotics, in order to promote and protect public health.
Dynamiczne skalowanie wielowymiarowe w analizie zmian struktury zatrudnienia w krajach Unii Europejskiej w latach 1999–2016
Authors: Markowska Małgorzata , Sokołowski Andrzej , Strahl Danuta
Published: December 2019

Skalowanie wielowymiarowe to metoda pozwalająca na przedstawienie obserwacji złożonych w przestrzeni o mniejszej liczbie wymiarów (zazwyczaj na płaszczyźnie) w taki sposób, aby macierz odległości liczonych na płaszczyźnie była jak najbardziej podobna do macierzy liczonej w przestrzeni oryginalnej. W pracy przedstawiono propozycję wykorzystania tego podejścia w analizie struktur przestrzenno-czasowych. Struktury są opisane udziałami, zatem nie jest konieczna procedura doprowadzania udziałów do porównywalności ze względu na jednostkę miary. Dla każdej jednostki czasu przeprowadzane jest osobne skalowanie wielowymiarowe. Ciąg wyników pozwala śledzić przemieszczanie się badanych obiektów względem innych w zbiorze. Te trajektorie można aproksymować funkcjami trendu. Rozważany przykład merytoryczny to analiza struktur zatrudnienia w 28 krajach Unii Europejskiej w latach 1999–2016. Struktury te liczone są w podziale na 10 zagregowanych sekcji.
Effects of Natural Geographic Features on the Manufacturing Industry in Sanliurfa, Turkey
Authors: Şahinalp Mehmet Sait
Published: December 2019

Geographical features of a place have an important effect on distribution, location, aglomeration and a variety of industrial activities. Social and economical features, along with natural geographic features such as geology, geomorphology, climate, natural vegetation, soil properties and hydrographic features also have a significant effect on industry. This study aims at determining how physical geographic features affect categories of industrial activities in Sanliurfa. For this purpose, firstly, physical geographic features of Sanliurfa and statistical data on agricultural and industrial activities in Sanliurfa were obtained. Then, effects of these physical features on other economic activities and the influence of those features on the distribution of industrial plants and industrial activities were analysed in terms of distribution, relation and casuality principles. Geological formations in Sanliurfa province occured in Neogene and also in Quaternary. These formations mostly consist of Neogene limestone, Quaternary basaltic volcanic rocks and alluvial soils. Geomorfically Sanliurfa is a slightly hilly place with plateaus and plains. The main river in Sanliurfa is the Euphrates – the biggest river of Turkey. Naural vegatation of Sanliurfa consists of steppe. These physical geographic fetaures of Sanliurfa cause intensive agricultural activites all across the province. Sanliurfa province covers 18,584 km² and 60% of this area is convenient for agriculture. As a consequence, the majority of manucturing industry in Sanliurfa is agro-based, such as food, textile, mill and apparel industries. While these categories constitute 65.43% of all industrial enterprises, the share of enterprises involving stone, clay, glass, and concrete industry is 11%, and lumber and wood industry share is only 2%.
Kierunki przemian gospodarczych gminy Wilkowice w powiecie bielskim w województwie śląskim
Authors: Tkocz Maria
Published: December 2019

Jedną z nowych form zagospodarowania obszarów wiejskich jest tworzenie na ich terenie stref aktywności gospodarczej. Są one jednym z istotnych czynników kształtujących wielofunkcyjność gmin wiejskich. Analiza funkcjonowania takiej strefy w gminie Wilkowice w latach 2006–2018 jest celem niniejszej publikacji. Przedstawiono także czynniki rozwoju gminy Wilkowice w przeszłości. Gmina położona malowniczo na obszarze Bramy Wilkowickiej, na zboczach Beskidu Śląskiego i Małego, rozwijała się dzięki swoim walorom turystycznym i tradycjom uzdrowiskowym. W warunkach gospodarki rynkowej rozwój funkcji turystycznej został zahamowany. Poszukując nowych czynników ożywienia gospodarki, władze gminy rozpoczęły prace nad uruchomieniem strefy gospodarczej położonej z dala od terenów mieszkaniowych i turystycznych. Zaprojektowano strefę o powierzchni około 15 hektarów, wybudowano drogę o długości 1528 m wyposażoną w niezbędne media oraz z dogodnym dojazdem do trasy szybkiego ruchu S-1. W strefie w latach 2011–2018 funkcjonowało 15 nowych zakładów przemysłowych, a kolejne są w budowie. Efekty gospodarcze wynikające z działalności zakładów w strefie, w której jest zatrudnionych około 2 tys. osób, stanowią podstawę do dalszego stałego i zrównoważonego rozwoju gminy, wpływając pośrednio na zintensyfikowanie turystyki poprzez modernizację infrastruktury, powstanie nowych obiektów noclegowych oraz organizację imprez turystycznych. Gmina może być dobrym przykładem wielofunkcyjnego rozwoju, opartego na współistnieniu turystyki i przemysłu.
Planowanie rozwoju lokalnego jako samorządowe narzędzie kształtowania funkcji usługowej gminy Moryń
Authors: Szostak Daniel
Published: December 2019

Artykuł zawiera przegląd zagadnień dotyczących problematyki planowania rozwoju funkcji usługowej na poziomie lokalnym, ze szczególnym uwzględnieniem opracowywania i wdrażania lokalnej strategii rozwoju gminy na przykładzie gminy Moryń. Pokazano korzyści, jakie daje lokalnej gospodarce opracowanie strategii rozwoju funkcji usługowej, oraz wskazano kierunki działania strategicznego na podstawie inwentaryzacji dostępnych zasobów endogenicznych. Ponadto pokazano, jak analizowana gmina drogą ewolucji i przemian strategicznych z realizacji funkcji rolniczej poprzez funkcję rolniczo-usługową przeszła do realizacji funkcji usługowej w dziedzinie turystyki. Badania przeprowadzone na potrzeby niniejszego artykułu stanowią uzupełnienie podobnych badań prowadzonych w innych gminach województwa zachodniopomorskiego oraz w całej Polsce. Problematyka badań nad rozwojem funkcji usługowej dla konkretnej gminy oraz przygotowana na jej potrzeby inwentaryzacja zasobów endogenicznych mają charakter unikatowy i oryginalny.
Hypo- versus hyper-thyroidism in 2 cats: the culprit for miliary dermatitis/hypersensitivity versus growth retardation
Authors: ERDOĞAN Songül , URAL Kerem , ERDOĞAN Hasan
Published: December 2019

In the present case series 2 different cats with diagnosis of hypo- versus hyper-thyroidism with distinct clinical signs were reported. The first case was a 3-month-old male domestic short-hair kitten was presented with a disproportionate dwarfism. Radiographic examination of the long bones revealed epiphyseal dysgenesis and delayed epiphyseal ossification. Congenital primary hypothyroidism was established by low serum total thyroxine. Initial treatment composed of levothyroxine. The second case was referred to the clinic with unresolved dermatological problems. On referral alopecia, extensive crusting and matting of the haircoat were evident. Hyperthyroidism and related military dermatitis was detected based on elevated serum total thyroxine and free T4 levels along with skin punch biopsy results. Therapeutical armamentarium composed of methimazole and hyperimmune milk factor. Early recognition, diagnosis and treatment intervention all resulted in clinical remission and relief of clinical signs accompanied by normal thyroidal function and laboratory results in both cats.
Regional engineering geology: a history of the development of theory and methodology
Authors: Trofimov V. T. , Krasilova N. S.
Published: December 2019

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Membrane-Tethered Mucin-like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus
Authors: Delaveris Corleone , Webster Elizabeth , Banik Steven , Boxer Steven , Bertozzi Carolyn
Published: December 2019

The mechanism(s) by which cell-tethered mucins modulate infection by Influenza A viruses (IAVs) remains an open question. Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic acids of cell-tethered mucins. To elucidate the molecular role of mucins in flu pathogenesis, we constructed a synthetic glycocalyx to investigate membrane-tethered mucins in the context of IAV binding and fusion. We designed and synthesized lipid-tethered glycopolypeptide mimics of mucins and added them to lipid bilayers, allowing chemical control of length, glycosylation, and surface density of a model glycocalyx. We observed that the mucin mimics undergo a conformational change at high surface densities from a compact to an extended architecture. At high surface densities asialo mucin mimics inhibited IAV binding to underlying glycolipid receptors and this density correlated to the mucin mimic’s conformational transition. Using a single virus fusion assay, we observed that while fusion of virions bound to vesicles coated with sialylated mucin mimics was possible, the kinetics of fusion were slowed in a mucin density-dependent manner. These data provide a molecular model for a protective mechanism by mucins in IAV infection, and therefore this synthetic glycocalyx provides a useful reductionist model for studying the complex interface of host-pathogen interactions.
Thermodynamic and Kinetic Parameters for Calcite Nucleation on Peptoid and Model Scaffolds - a Step Toward Nacre Mimicry.
Authors: Nielsen Anne Rath , Jelavic Stanislav , Murray Daniel , Rad Behzad , Andersson Martin , Ceccato Marcel , Mitchell Andrew , Stipp Susan , Zuckermann Ron N. , Sand Karina
Published: December 2019

To establish an approach for a bulk upscaling of a composit material consisting of calcium carbonate and tunable peptoids we here combined three distinct approaches to thoroughly access the underlying kinetic and thermodynamic driving forces for CaCO3 formation on peptoid polymers. We derived the net interfacial free energy for calcite formation on the nanosheets and self-assemblage monolayers of the sheets constituent functional groups (carboxyl, amine and a 1:1 mix) using: nucleation experiments, dynamic force spectroscopy and theoretical modeling (COSMO-RS). We applied nucleation theory to the results and obtain insight into conditions were we can obtain favorable nucleation conditions on the polymers in a highly controlled manner.
Spotting Differences in Molecular Dynamic Simulations of Influenza A M2 Protein-Ligand Complexes by Varying M2 construct, Lipid Bilayer and Force Field
Authors: Kolokouris Dimitrios , Kalenderoglou Iris , Lagarias Panagiotis , Kolocouris Antonios
Published: December 2019

We studied by molecular dynamic (MD) simulations systems including the inwardclosed state of influenza A M2 protein in complex with aminoadamantane drugs in membrane bilayers. We varied the M2 construct and performed MD simulations in M2TM or M2TM with amphipathic helices (M2AH). We also varied the lipid bilayer by changing either the lipid, DMPC or POPC, POPE or POPC/cholesterol (chol), or the lipids buffer size, 10x10 Å2 or 20x20 Å2. We aimed to suggest optimal system conditions for the computational description of this ion channel and related systems. Measures performed include quantities that are available experimentally and include: (a) the position of ligand, waters and chlorine anion inside the M2 pore, (b) the passage of waters from the outward Val27 gate of M2 S31N in complex with an aminoadamantane-aryl head blocker, (c) M2 orientation, (d) the AHs conformation and structure which is affected from interactions with lipids and chol and is important for membrane curvature and virus budding. In several cases we tested OPLS2005, which is routinely applied to describe drug-protein binding, and CHARMM36 which describes reliably protein conformation. We found that for the description of the ligands position inside the M2 pore, a 10x10 Å2 lipids buffer in DMPC is needed when M2TM is used but 20x20 Å2 lipids buffer of the softer POPC; when M2AH is used all 10x10 Å2 lipid buffers with any of the tested lipids can be used. For the passage of waters at least M2AH with a 10x10 Å2 lipid buffer is needed. The folding conformation of AHs which is defined from hydrogen bonding interactions with the bilayer and the complex with chol is described well with a 10x10 Å2 lipids buffer and CHARMM36.
Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation
Authors: Schuster Ramona , Anton Vincent , Simões Tânia , Altin Selver , den Brave Fabian , Hermanns Thomas , Hospenthal Manuela , Komander David , Dittmar Gunnar , Dohmen R Jürgen , Escobar-Henriques Mafalda
Published: December 2019

Mitochondria are essential organelles whose function is upheld by their dynamic nature. This plasticity is mediated by large dynamin-related GTPases, called mitofusins in the case of fusion between two mitochondrial outer membranes. Fusion requires ubiquitylation, attached to K398 in the yeast mitofusin Fzo1, occurring in atypical and conserved forms. Here, modelling located ubiquitylation to α4 of the GTPase domain, a critical helix in Ras-mediated events. Structure-driven analysis revealed a dual role of K398. First, it is required for GTP-dependent dynamic changes of α4. Indeed, mutations designed to restore the conformational switch, in the absence of K398, rescued wild-type-like ubiquitylation on Fzo1 and allowed fusion. Second, K398 is needed for Fzo1 recognition by the pro-fusion factors Cdc48 and Ubp2. Finally, the atypical ubiquitylation pattern is stringently required bilaterally on both involved mitochondria. In contrast, exchange of the conserved pattern with conventional ubiquitin chains was not sufficient for fusion. In sum, α4 lysines from both small and large GTPases could generally have an electrostatic function for membrane interaction, followed by posttranslational modifications, thus driving membrane fusion events.
Factors associated with mortality in persons co-infected with tuberculosis and HIV in Suriname: a retrospective cohort study
Authors: Stijnberg Deborah , Commiesie Eric , Marín Diana , Schrooten Ward , Perez Freddy , Sanchez Mauro
Published: December 2019

Objective. To identify socio-demographic and clinical factors associated with mortality among persons with tuberculosis (TB) and TB/HIV co-infection in Suriname.

Methods. This was a retrospective cohort study using data from the national TB and HIV databases for 2010 – 2015. The survival probability of TB and TB/HIV co-infected patients was analyzed using the Kaplan-Meier estimates and the log-rank test. A Cox proportional hazard model was applied.

Results. The study showed that HIV-seropositivity (aHR: 2.08, 95%CI: 1.48 – 2.92) and older age (aHR: 5.84, 95%CI: 3.00 – 11.4) are statistically associated with higher mortality. For the TB/HIV co-infected patients, TB treatment (aHR: 0.43, 95%CI: 0.35 – 0.53) reduces the risk of death. Similarly, HIV treatment started within 56 days (aHR: 0.15, 95%CI: 0.12 – 0.19) and delayed (aHR: 0.25, 95%CI: 0.13 – 0.47) result in less hazard for mortality; Directly-Observed Treatment (aOR: 0.16, 95%CI: 0.09 – 0.29) further reduces the risk.

Conclusions. The Ministry of Health of Suriname should develop strategies for early case-finding in key populations, such as for HIV and TB in men 60 years of age and older. Implementation of Isoniazid Preventive Therapy for HIV should be pursued. Scaling up TB and HIV treatment, preferably through supervision, are essential to reducing the TB/HIV mortality.
La experiencia: Requisito social para el emprendimiento del optometrista
Authors: Riccardi Palacios Jhonny Gustavo , Zurita Gaibor Javier Antonio , Pérez Muñoz Felicita Damaris , Silva Vega Efraín Orlando
Published: December 2019

Los ojos son uno de los órganos más complejos e interesantes del cuerpo humano. Son además la principal vía para percibir y admirar el mundo exterior. La visión es uno de los sentidos más importantes, puesto que sirven para entender el ambiente en que vivimos e interactuar con él. El objetivo de esta investigación es determinar las principales causas del empirismo dentro del área óptica y el profesional de la optometría. La metodología de trabajo utilizada fue descriptiva y explicativa, dando como resultado a conocer que la población emprende de forma equivocada en cualquier área de inversión sin tomar en cuenta las consecuencias que afectarán las necesidades de los usuarios. Como conclusión se puede determinar que es necesario que los profesionales de la optometría logren incentivar a los usuarios al uso de las ópticas calificadas con los conocimientos adecuados para brindar un servicio de calidad, calidez y eficacia.
Legally relevant messages in the inter-branch analogy of the law
Authors: Bogdan Varvara , Korotkikh Olga
Published: December 2019

The article deals with the specifics and prospects of using legally relevant messages in different branches of law. Also the authors analyze the court cases in order to determine the problems of efficiency of such using. Among the significant factors preventing the application of article 165.1 of the Civil code of the Russian Federation in other branches of law, the authors draw attention to the imperfection of the norm itself, and also emphasize its public nature in some cases. The authors note that the messages as part of the procedure for the seizure of land have legal relevance for their owners. The methodological basis of the research is a set of general scientific and private scientific methods such as: system-structural, analysis, formal-legal, logical and others. Scientific novelty of the research is that the authors, on the basis of theoretical insights, legislation and court cases propose to identify the legally relevant messages in the administrative procedure for searching holders of the seizuring property as appropriate and necessary way of ensuring the rights and lawful interests of these holders.
Humanitarian Access in conditions Armed Conflict: The International Legal Aspect
Authors: Rylskaya Marina
Published: December 2019

The article reveals a number of legal issues related to humanitarian assistance; some of them are being regulated from the point of view of International Humanitarian Law. It is also stressed that the current system of international relations is not always capable of maintaining peace and security, which leads to the shift of the international community's efforts from the level of forceful resolution of conflicts to the format of humanitarian Cooperation.
Investigating the health belief model structures regarding the preventive factors from the occurrence of accidents and injuries in children under 5 years of age in Fasa city
Authors: Dehghani Seyedeh Samaneh , Jafarzadeh Saeedeh , Azadkhah Fatemeh , Bazrafshan Mohammad-Rafi , Harsini Pouyan Afzali , Jeihooni Ali Khani
Published: December 2019

Injuries caused by the accidents are one of the major causes of
death in children under 5 years of age. One of the important indexes of the development
and health optimization in countries is the mortality rate of children
under age 5.
Aim: The purpose of this study is investigating the health belief model structures
regarding the preventive factors from the occurrence of accidents and injuries
in children under age 5.
Material and methods: Present cross sectional descriptive study has been
conducted on 270 mothers having a child under 5 years of age who have referred
to the health centers in Fasa city in 2017. Based on the health belief model, the
information are collected via questionnaires and the obtained data are analyzed
by the multiple regression SPSS-20.
Results and discussion: The predictive structures of this study are the
perceived barriers, perceived susceptibility, perceived benefits and self-efficacy.
The average score of perceived barriers is 62.24, perceived susceptibility is 45.25,
the perceived benefits is 61.22 and the self-efficacy is 50.49. Therefore, the studied
variables predict 33.6% of whole performance. Also, except the perceived
barriers, a significant and direct relationship is observed between the structure of
mothers performance and other structures (P < 0.05).
Conclusions: According to the average scores of awareness and performance
of mothers and other health belief model structures, it is suggested that, training
programs in the form of training packages be performed based on this model in
order to develop the preventive behaviors from the occurrence of accidents and
injuries in children.
Comunicação e Consumo da Cidade: entre espaços construídos e espaços vividos
Authors: Hoff Tânia Cezar , Oliveira Adriana Lima
Published: December 2019

Abordamos, neste artigo, o consumo da cidade a partir da produção de sentidos e de discursos presentes em projetos de reurbanização da região central da cidade de São Paulo, lugar que propicia diálogos, debates e embates característicos do nosso espaço-tempo histórico e nos permite descortinar os discursos institucionalizados sobre áreas urbanas de interesse de várias ordens. Definimos como questão a ser debatida a produção de sentidos sobre a cidade de São Paulo, notadamente aquela promovida no âmbito de projetos de reurbanização, bem como a concepções de cidade que justificam intervenção no centro desta metrópole brasileira. Para tanto, o corpus a ser analisado é formado por três propostas de reurbanização na região central da cidade de São Paulo: Projeto Nova Luz, 2011; Projeto Centro Novo, 2017; e Projeto Campos Elísios Vivo, 2018. Tendo como principal inspiração teórico-metodológica a análise de discurso de linha francesa, mobilizamos estudiosos do campo da comunicação, dos estudos do consumo e da cidade que fundamentam teoricamente nossas reflexões.
Lembrar Virilio, pintor das antiformas
Authors: Quiroga Tiago , Agostineti Kaique
Published: December 2019

Em 10 de setembro de 2018, morria, aos 86 anos, Paul Virilio, vítima de ataque cardíaco, na cidade litorânea de La Rochelle, onde morara desde sua aposentadoria, em 1999, pela École Speciale d’Architecture (ESA) de Paris. A fatalidade e a crescente importância de suas ideias em diversos campos do saber, entre eles o da comunicação, orientam a realização do presente ensaio. Seguindo apontamentos biográficos e marcos conceituais, procura-se rememorar sua obra, sinalizando problemas e hipóteses que, decisivos, nos ajudam a compreender fenômenos contemporâneos. Tal itinerário encontra-se organizado em cinco chaves de leitura: Virilio, filho da guerra total; Pintor das antiformas; Um arquiteto prático da inclinação; O anarcocristão; O crítico da arte tecnológica.
Etnografia em uma "cidade em movimento": O evento Picnik e a ocupação do espaço público em Brasília
Authors: Martinelli Fernanda Casagrande , Oliveira Alice Roberte de
Published: December 2019

O artigo é uma reflexão sobre a economia criativa enquanto um fenômeno urbano, que emerge da interação constante e intensa entre indivíduos. Viver na cidade é participar de uma multiplicidade de hierarquias e de sistemas, de temporalidades e de situações, de agitações e de estímulos, que condicionam estilos de vida, conforme George Simmel (1987) descreve. Através de etnografia no evento Picnik, observamos de que forma a sociabilidade e a ocupação do espaço público brasiliense são favorecidas pela economia criativa.
Application of RAPD Markers on Sex Determination of Papaya (Carica papaya)
Authors: Prihatini Riry , , Noflindawati , Budiyanti Tri
Published: December 2019

Molecular sex determination of five varieties of Indonesian papaya were investigated using RAPD (Random Amplified Polymorphism DNA) markers. Overall, 12 of 14 primers produced polymorphic bands on either several or all tested varieties. The OPC04 and RAPD2 markers could be used determined sex types on all varieties, whereas others primers are only on certain varieties. The Tangkai Ungu variety can be differentiate by markers: OPA11, OPA14, OPC14, RAPD2, RAPD3, and RAPD5; the Lokal Sumani can be determine using markers: OPA01, OPA11, OPA14, OPC01, OPC04, RAPD2, RAPD3, RAPD5, and RAPD6; the Merah Delima could be determined using OPC04, OPN09, RAPD2, and RAPD5; the Dampit could be determined using OPC01, OPC04, RAPD2, and RAPD6; whereas the Sicincing Panjang could be determined using OPA04, OPA11, OPA14, OPC04, RAPD2, and RAPD3.
Perbedaan Respon Seleksi, Kemajuan Seleksi, dan Jumlah Segregan Transgresif Hasil Persilangan Tomat Suka Naungan dengan Tomat Peka Naungan
Authors: Ritonga Arya Widura , Syukur Muhamad , Chozin Muhamad Achmad , Maharijaya Awang , Sobir ,
Published: December 2019

Penelitian ini bertujuan untuk mengevaluasi kemajuan seleksi dan segregan transgresif tanaman tomat generasi awal di bawah naungan. Penelitian ini terdiri atas 2 percobaan, dimana percobaan pertama dilaksanakan pada Juli – Oktober  2016 sedangkan percobaan kedua dilaksanakan pada Agustus – November 2017. Genotipe tomat  SSH3 (suka naungan), 4979 (peka naungan) dan populasi F2 hasil persilangan SSH3 dan 4979 ditanam di Kebun Percobaan IPB, Pasir Kuda, Ciomas, Bogor pada percobaan pertama. Sebanyak 13 genotipe F3 (hasil seleksi populasi F2 pada percobaan 1), genotipe SSH3, genotipe 2979 dan populasi F2 hasil persilangan SSH3 x 4979 ditanam pada percobaan 2. Evaluasi kemajuan seleksi dan segregan hasil persilangan tomat suka naungan dan peka naungan, menunjukkan bahwa karakter jumlah buah dan bobot buah tomat menghasilkan nilai persentase kemajuan seleksi harapan yang tinggi namun menghasilkan persentase kemajuan seleksi yang lebih rendah. Karakter fruit set menghasilkan nilai persentase kemajuan seleksi harapan dan persentase kemajuan seleksi yang sama-sama tinggi. Sementara karakter vegetatif dan karakter buah tomat menghasilkan persentase kemajuan seleksi harapan dan kemajuan seleksi yang sama-sama rendah. Segregan transgresif banyak diperoleh berdasarkan karakter fruit set, lebih sedikit dihasilkan berdasarkan karakter jumlah dan bobot buah per tanaman, dan tidak dihasilkan berdasarkan karakter vegetatif dan karakter buah. Hal ini mengindikasikan bahwa karakter jumlah buah dan bobot buah per tanaman tomat lebih banyak dikendalikan oleh gen-gen non aditif, karakter fruit set lebih banyak dikendalikan gen-gen aditif pada kondisi di bawah naungan, dan tidak terdapat keragaman genetik pada karakter vegetatif dan karakter buah tanaman tomat pada populasi yang digunakan.
Tasas de incidencia y mortalidad por cáncer de mama en el área metropolitana de Bucaramanga en el período 2001-2005
Authors: Osma Zambrano Sonia Esperanza , Uribe Claudia
Published: December 2019

Introducción: El cáncer de mama es un problema de salud pública a nivel mundial; es por eso que conocer las tasas de incidencia y mortalidad en nuestra región es prioritario para evaluar globalmente el estado de salud-enfermedad secundario de esta lesión tumoral. Objetivo: Describir las tasas de incidencia y mortalidad por cáncer de mama en las mujeres del Área Metropolitana de Bucaramanga (AMB) durante el primer quinquenio de funcionamiento del Registro Poblacional de Cáncer del AMB (RPC-AMB) Metodología: Los casos de cáncer de mama invasivos, primarios en mujeres, diagnosticados durante el período 2001-2005 se seleccionaron de la base del RPC-AMB. Los datos de población y mortalidad se obtuvieron del Departamento Administrativo Nacional de Estadística (DANE), Secretaria de Salud Departamental y Registraduría Nacional de la Nación. De la misma manera, se estimaron tasas crudas de incidencia (TC) y mortalidad (TMC) totales y específicas por grupos de edad y las tasas de incidencia estandarizada (TEE) y mortalidad ajustada por edad (TMEE) para el quinquenio correspondiente por el método directo.  Resultados: Se identificaron 999 casos de cáncer de mama invasivo. Se excluyeron del análisis once pacientes después de completarse el segundo proceso de validación. La TC global fue de 37.8/100.000 mujeres y la TEE global  fue de 38.9/100.000 mujeres. La TMC  global fue de 17.3/100.000 mujeres y la TMEE fue de 17.5/100.000 mujeres. La mortalidad acumulada a 5 años por cáncer de mama para la cohorte fue de 44.4 % (IC95% 41.2-47.6). La sumatoria de tiempo de seguimiento fue de 72.520.6 meses o 6.043.4 años, con un  rango interquartil de (37.9-114.6). La densidad de incidencia fue de 4.32 muertes por cáncer de mama invasivo por cada 1.000 mujeres por meses de seguimiento (IC 95% 3.9-4.8). Siendo la densidad de incidencia mayor para las pacientes menores de 44 años con 4.55 (IC 95% 3.61-5.73) y para las mayores de 65 años con 6.18 (IC 95% 5.06-7.55). Conclusión. Este informe determina en forma global el alcance de las medidas de control del problema de cáncer de mama en nuestra región sugiriendo dificultades en el diagnóstico temprano y tratamiento adecuado. Las tasas de mortalidad por cáncer  de mama en el AMB fueron más altas en pacientes mayores de 65 años que en los menores de 44 años. Por lo tanto, es necesario profundizar en los determinantes de mortalidad en estos dos grupos  poblacionales.[Osma-Zambrano SE, Uribe-Pérez CJ. Tasas  de incidencia y mortalidad por cáncer de mama en el área metropolitana de Bucaramanga en el período 2001-2005. MedUNAB 2014; 16(3):101-111]
Tuberculosis en Colombia, de la historia al entendimiento de la enfermedad
Authors: Ordóñez Sánchez Sergio Alexander , López Osma Fernando Augusto
Published: December 2019

Introducción: La Tuberculosis es una de las enfermedades más antiguas que ha afectado al hombre, siendo en el pasado la principal causa de muerte en personas jóvenes y en la actualidad un grave problema de salud pública en Colombia. A pesar de que existen medios preventivos para evitar su incremento en la comunidad, la incidencia de la tuberculosis ha seguido aumentando en nuestro país. Por lo que se requiere reforzar la prevención primaria y secundaria con medidas que lleven a mejorar la calidad de vida de los pacientes, garantizando la eficacia y la oportunidad del diagnóstico bacteriológico y cortando la cadena de transmisión de persona enferma a sana, mediante la búsqueda, localización precoz y tratamiento oportuno. Por tanto, se debe fortalecer las alianzas entre las entidades de salud con el fin de desarrollar e implementar estrategias de participación comunitaria para la prevención y el control de la enfermedad. A pesar de poseer nuevos conocimientos sobre la biología y la epidemiologia de esta entidad, consiguiendo alterar efectivamente la historia natural de la misma, no se ha logrado erradicar la enfermedad definitivamente, debido a múltiples razones, como son, entre otras, la resistencia a fármacos, la asociación con el VIH-SIDA, y las migraciones (desplazados), lo que confiere un reto para lograr los objetivos trazados por los programas de salud pública a nivel  mundial. El objetivo de este artículo es obtener una visión amplia de la enfermedad, desde sus primeras apariciones hasta la actualidad, mediante la revisión de algunos aspectos de la fisiopatología, diagnóstico y tratamiento. Metodología: se realizó búsquedas en bases de datos y motores de búsqueda en el periodo 1978-2014. Fueron seleccionados 128 artículos. Conclusiones: La expansión de la TBC, no es más que el reflejo del profundo deterioro de las condiciones de vida de millones de personas en todo el planeta y continúa siendo una causa importante de morbilidad y mortalidad en el mundo entero, exacerbada en los últimos años por varios factores entre ellos la infección por el virus de la inmunodeficiencia humana y por la emergencia de la multirresistencia.[Ordóñez SA, López FA. Tuberculosis en Colombia, de la historia al entendimiento de la enfermedad. MedUNAB 2014; 16(3):127-142]
Analisis dan Strategi Peningkatan Pendapatan Asli Daerah (PAD) di Kabupaten Gunungkidul
Authors: Nilawati Evi
Published: December 2019

Regional Original Revenue (PAD) has a very large contribution to the Regio-nal Budgeting (APBD) to finance the administration and service processes of govern-ment affairs and regional development. The present research aims to determine how to improve PAD and build strategy of action plan  for increasing it in Gunungkidul Regency. This study used descriptive qualitative method. Informants were taken by purposive sampling. Data collecting techniques are observations, interview with Local Agency Organizations (OPD) which are responsible for PAD generation, and docu-mentations or secondary data, i.e. APBD, PAD, and other relevant data. The results of the study showed that the development of Gunungkidul PAD experienced a significant development as big as 25,97%. The PAD contribution to regional income or fiscal decentralization rate is 11,73%. The strategy to increase the PAD is built by a formulating action plan for accelerating it. Based on this results, it is suggested that the program to increase competency and commitment of regional tax-retribution managers for each revenue management of local agency, provide a program to increase the PAD and implementation of the action plan to increase it, use information and communi-cation technology for the management of each PAD lines, and optimally stakeholders cooperation building.
Nas fissuras da história: o movimento lésbico no Brasil
Authors: Lino Tayane Rogeria
Published: December 2019

Este trabalho tem por objetivo realizar uma síntese histórica do Movimento de Mulheres Lésbicas no Brasil (MLB), a partir da segunda metade do século XX, como um requisito da disciplina História e Teoria em Psicologia Social, oferecida no programa de pós-graduação em Psicologia da UFMG. A revisão de literatura sobre o tema aponta que pouco se tem notícia acerca da emergência dos grupos lésbicos no Brasil, as informações aparecem difusas nos estudos sobre a história do Movimento Feminista (MF) e do Movimento Homossexual (MH), o que exige dos/as leitores/as a construção de uma história dentro da exposição da história. Os registros de movimentos organizados de lésbicas são marcados por negociações permeadas de conflitos, debates,  encontros e desencontros com os movimentos supracitados. Se a história é o resultado da tentativa de uma interpretação de fatos, uma análise de um momento específico, ela nunca será uma verdade única/singular e sim fragmentos de fatos que produzem redes de sentidos e hierarquias sócio-históricas. Portanto, como aponta Foucault (1979), a história instaura regimes de verdades, nestes termos o que a história não diz nunca existiu. Assim a luta pela construção de uma epistemologia da história das mulheres lésbicas busca o reconhecimento da existência, visibilidade e a inserção na vida pública.
Patriarcado e capital: uma união letal para as mulheres
Authors: Gayozo Bruna Aparecida Azevedo , Santos Danielly Fernanda Azevedo
Published: December 2019

A persistência da violência a que as mulheres são submetidas diariamente no Brasil nos indica que este é um problema estrutural e que não se concentra no lócus das relações pessoais apenas. Existe todo um sistema complexo de relações que contribuem e se beneficiam da manutenção do status de inferioridade ao qual fomos educadas. Os corpos femininos são domesticados por uma organização entre sistema capitalista e patriarcado, de forma que todas as transgressões que fogem do que é vantajoso para este sistema é punido violentamente.
Feminismos e violências de gênero: paradoxos e ambiguidades na aplicação da Lei Maria da Penha pelo sistema de justiça
Authors: Nichnig Claudia Regina , Bragagnolo Regina Ingrid
Published: December 2019

A aposta política que os movimentos das mulheres e feministas têm realizado ao eleger os ordenamentos jurídicos como uma estratégia central no combate à “violência doméstica e familiar contra a mulher”, coloca em pauta a necessidade de monitorar as estratégias que os operadores do direito utilizam na aplicação dos dispositivos da Lei Maria da Penha. Assim, a presente artigo aponta elementos para a compreensão de como  operadores do direito tem utilizado a Lei 11.340/2006 no tratamento da “violência doméstica e familiar contra a mulher”. Essa pesquisa descrever o campo de práticas e saberes em torno da aplicação dessa norma jurídica na dinâmica de atendimento da 3ª Vara Criminal e Juizado de Violência Doméstica e Familiar contra a Mulher da Região Metropolitana de Florianópolis, quando ainda não haviam sido criados os Juizados de Violência Doméstica e Familiar contra a Mulher em Santa Catarina. Nesse estudo, apresentamos as tensões, ambigüidades e particularidades evidenciadas tanto nas interpretações jurídicas quanto em seus desdobramentos nas práticas institucionais, visando apontar elementos reflexivas de como se dava a atuação dos operadores do direito em uma instituição da justiça, e como ela se situava em relação às reivindicações políticas dos movimentos feministas.
Kielitietoisuus-käsite ja kieli-ideologiat helsinkiläisten peruskoulujen opetussuunnitelmadiskursseissa
Authors: Suuriniemi Salla-Maaria
Published: December 2019

This article critically explores the discourses surrounding the concept of language awareness in the school-specific curricula of basic schools in Helsinki. The school curricula have been designed at the process of reforming the Finnish national core curriculum for basic education and should be aligned with it. The newest Finnish national core curriculum for basic education came in to effect in 2016. Language awareness is one of the core concepts defining language education in the national curriculum and multilingual learning is an essential part of it. However, results of this study show that the school curricula do not always support multilingual outlook, but instead reflect monolingual practices. The most important theoretical tools in this study are the semiotic processes iconization and erasure defined by Judith T. Irivine and Susan Gal. The data for discourse analysis consists of 92 texts collected from the website http://ops.edu.hel.fi   in August 2018. This article is unique in analyzing school-specific curricula.
Miten kääntäjäkoulutus voi tukea kielenelvytystä?
Authors: Kuusi Päivi
Published: December 2019

In this paper, translator training is discussed as a form of language revitalisation. Translation has the potential to stimulate the development of an underused language, but this potential is often accompanied by a risk of unwanted source-language influence. In translator training, minority language translators learn to control this influence and critically assess their own translation solutions. If translator training succeeds in empowering speakers of an endangered language to translate, and to translate with an awareness of how their translations might influence the development of the minority language, it can justly be considered language policy par excellence.
NARRATION AS A MEANS OF COMMUNICATION IN SELECTED NOVELS BY J.M.COETZEE: WAITING FOR BARBARIANS AND FOE
Authors: Waham Jihad Jaafar , Othoman Wan Mazlini
Published: December 2019

Narrations become very important such that, we tend to try to make others want to fit into them to identify with us, which is why narrative is often used in the recount of events, the past, geared to justify the systems of domination and control evident in the plight of South Africans during the apartheid period. Moreover, the narrative also shelters realities against which the truth can be judged, and they also have some sense or measure of proper world order, against which moral action can be judged. As such, narration point of view can also be determined through the perspective the story is being told. Be it the first person narrative where the author or narrator refers to himself with the personal pronoun of I, me, my, myself, however, this mode of narration may also use second and third-person pronouns in addition to the first-person point. Wherefore, the second Person narrator sees the author or narrator addresses the reader directly as you, and may use the words we and us as well in the process. The third person pronouns still could be used in a novel, in addition, where the narrator or author refrains from using a first or second person and only refers to characters as he or she or it to demonstrate his narrative techniques in this process. To this effect narrative technique employed by J.M. Coetzee’s as accounted in the selected novels used for this paperwork to explore Coetzee’s capabilities of developing a true sense of self as well as communicate to others through the Narration
EXPLORING GENERIC STRUCTURE POTENTIAL OF SELECTED EDITORIALS IN THE MYANMAR TIMES NEWSPAPER
Authors: Kyaw Ae Mon , Zhiying Xin
Published: December 2019

Systemic Functional Linguists introduced Generic Structural Potential (GSP) that can be used to distinguish different social activities of a text. A variety of researches have been conducted on Generic Structural Potential of the editorials of other countries. However, no research has been conducted about the editorials of Myanmar newspaper. Therefore, The Myanmar Times newspaper, written in English, is chosen to carry out a research. The aim of the research paper is to identify the schematic structural elements of the editorials in The Myanmar Times newspaper. The materials are measured using Generic Structure Potential proposed by Halliday and Hason (1985). The result of the study shows that there are two obligatory elements and five optional elements. Heading (H), and Contributing the Writer’s Opinion (O) are obligatory while Picture (P), Caption(C ), Addressing the issue (AI) , Background Information (BI), and Discussing the issue Raised (D) are optional elements. The sequence of the elements follows the procedure H^ (P)^{ *(BI) *(AI) *(D) }^O.
Gestión del paisaje vitivinícola en las Reservas de la Biosfera españolas
Authors: Baraja Rodríguez Eugenio , García de Celis Alipio José , Herrero Luque Daniel
Published: December 2019

Las Reservas de la Biosfera (RB) son ámbitos delimitados con el objetivo de conciliar la conservación de los valores naturales y culturales con el desarrollo sostenible. El presente artículo parte de la hipótesis de que esta figura de la UNESCO puede desempeñar una función clave en la tarea de aunar la conservación de la biodiversidad, el desarrollo territorial y el mantenimiento de los valores culturales asociados a los paisajes de la vid y el vino en entornos frágiles. El principal objetivo es presentar un primer balance de la importancia que desempeñan las Reservas de la Biosfera de España en la gestión del paisaje en general, y del viñedo en particular. Esa aproximación se realiza a partir de la consideración de las estrategias que afectan a los valores paisajísticos del viñedo contenidos en los planes de acción de las reservas. Asimismo, se cartografían y ponderan las superficies vitícolas de estos espacios y se realiza un análisis más en profundidad en aquellos casos en los que el viñedo, por su entidad o singularidad, ocupa un lugar destacado entre los cultivos.
El espacio rural de España: evolución, delimitación y clasificación
Authors: Molinero Hernando Fernando
Published: December 2019

El espacio rural de España es claramente dual: frente a la pérdida de peso del interior se consolida el auge y la densificación de la periferia y de las áreas de influencia urbana; un fenómeno tan llamativo que ha generado una fuerte preocupación por el vaciamiento rural, que, en diverso grado, afecta a una gran parte del continente europeo. El primer objetivo de este artículo es analizar la evolución y delimitación del ámbito rural español, su clasificación y cartografía. El segundo, diagnosticar la situación y valorar los planes para contribuir al desarrollo rural. El análisis ha contado con abundantes informes, trabajos teóricos y aplicados de distintas instituciones, organizaciones y colectivos, además de con una extensa bibliografía. A todo ello se ha superpuesto el tratamiento y procesado de bases de datos demográficos, económicos y sociales cuya representación cartográfica evidencia el fenómeno y su distribución territorial. Como resultado, se clasifica y cartografía el espacio rural español en dos categorías: la del rural profundo y estancado, por un lado, y la del intermedio y dinámico, por otro. Ambas se subdividen en varios tipos.
Análisis relacional en iniciativas socialmente innovadoras. El caso de estudio de Alianza Mar Blava (Ibiza-Formentera)
Authors: Herraiz Lizán Cristina , Vercher Savall Néstor , Esparcia Pérez Javier
Published: December 2019

Los estudios de desarrollo local, durante los últimos años, han recuperado la innovación social cómo perspectiva analítica de los cambios organizativos y procesos de transformación de las relaciones sociales en el territorio. Con ello, surge el interés de cómo estudiar lo intangible de esta dimensión del desarrollo local. A partir de aquí, el capital social cobra especial interés como enfoque teórico para poder interpretar el análisis relacional. Así, mediante el caso de estudio de una iniciativa socialmente innovadora (Alianza Mar Blava, en el área de Ibiza y Formentera), esta investigación identifica la red social de actores relevantes y caracteriza las redes personales y otros atributos de los actores clave (a partir de 35 entrevistas en profundidad). Para ello se utiliza la metodología de Análisis de Redes Sociales, combinando análisis estructural sociocéntrico con análisis atributivo egocéntrico. Los resultados para este caso de estudio ponen de relieve que el poder en la red se encuentra distribuido entre los diferentes perfiles socioprofesionales. Asimismo, los actores con mayor control sobre la red son mujeres y jóvenes con estudios superiores. A modo de conclusión, se reflexiona sobre las dinámicas de innovación y desarrollo que pueden promover redes sociales como las observadas en Alianza Mar Blava.