bluuebunny/crossref_metadata_2025 huggingface dataset:
Metal Halide Perovskite-based Heterojunctions for Green Ammonia Production: Material Engineering and Mechanistic Features
Authors: Malavasi Lorenzo , Tedesco Costanza , Simbula Angelica , Pau Riccardo , Saba Michele , Speltini Andrea , Profumo Antonella , Merlo Francesca , Armenise Vincenza , Listorti Andrea , Alothman Asma , Gregori Luca , Mosconi Edoardo
Published: October 2024

Designing innovative photocatalysts for nitrogen photofixation is becoming crucial for the development of carbon neutral ammonia production. Metal halide perovskites (MHPs) have been demonstrated to be effective materials to run a wide range of photoredox reactions mediated by solar light. Herein, we develop an innovative heterojunction based on the vacancy-ordered double perovskite Cs2SnBr6 and carbon nitride nanosheets and demonstrate its ability in running the nitrogen photofixation reaction to produce ammonia. We explore the full compositional range for the Cs2SnBr6/g-C3N4 system and identify an optimal range providing an ammonia evolution rate up to 260 μmol g-1 h-1, the highest value reported to date for a MHP-containing catalyst. Mechanistic insight into the photofixation reaction promoted by the heterojunction was obtained through a combination of advanced spectroscopy and computational modelling. Efficient ammonia production stems from an effective charge transfer from the perovskite to the nitrogen vacancies on the carbon nitride enabled by the absence of self-trapped excitons in Cs2SnBr6 which also provides additional reactive sites through bromide vacancies. This work, reporting an efficient MHP-based heterojunction for nitrogen photofixation and a clear definition of the underlying reaction mechanism, provides a catalyst design strategy that may pave the way for sustainable ammonia production.
Controlling Electrostatics to Enhance Conductivity in Structured Electrolytes
Authors: Hennes Logan , Behringer Chloe , Farshad Mohsen , Schaefer Jennifer L. , Whitmer Jonathan K.
Published: October 2024

Solid-state electrolytes are currently being explored as a safe material capable of addressing consumer energy-storage demands. Solid polymer electrolytes, in particular, offer a high energy density and improved safety when compared to liquid-based electrolytes, but tend to have a significantly lower ionic conductivity. We hypothesize structured ionic liquids can enhance conductivity. Here, we explore the performance of these materials through coarse-grained molecular dynamics simulation. While we observe similar phase behavior (incorporating solid, smectic, and liquid phases) to that seen in experiments, we also observe significantly more mobility in the cationic species compared to the anionic species before the system reaches an arrest transition. We further discuss how the general results within this paper can guide further studies and target the design of new highly conductive solid electrolytes with the potential to enable the use of multivalent ionic species as ion conductors.
Easily Accessible and Solution-Stable Ni(0) Precatalysts for High-Throughput Experimentation
Authors: Thomas Gilian , Cruise Odhran , Peel-Smith Daelin , Pipaon Fernandez Nahiane , Killeen Charles , Leitch David
Published: October 2024

We report the synthesis, characterization, and catalytic applications of N,N’-diaryl diazabutadiene (DAB) Ni(0) complexes stabilized by alkene ligands. These complexes are soluble and stable in several organic solvents, making them ideal candidates for in situ catalyst formation during high-throughput experimentation (HTE). We used HTE to evaluate these Ni(0) precatalysts in a variety of Suzuki and C–N coupling reactions, and they were found to have equal or better performance than the still ‘industry-standard’ Ni(0) source, Ni(COD)2.
GEOSPATIAL ANALYSIS OF HYDROLOGIC RESPONSE UNITS OF FLOOD INUNDATION AT DIFFERENT SUB-BASINS PARAMETERS IN TERENGGANU WATERSHED, MALAYSIA
Authors: Alkali Mohammed , Sufiyan Ibrahim , Dahiru M.K.
Published: October 2024

Flood is one of the natural events in our environment. It destroys and displaces naturally existing structures found within the Hydrologic Response Units (HRUs). These include the Land Cover/Land use, Soil structure and the topography or the terrain. The method applied was the used of ArcSWAT to determine those flooded sub-basins by simply delineating the whole watershed into different sub-basin parameters. The result proves that what determines the flood influence was the area of the sub-basin that contained the HRUs not the HRUs itself. Once the sub-basin was inundated, the flooded streams within the sub-basins were calculated as flood impact. in this analysis 5 number of sub-basins were flooded in the watershed of Terengganu. Sub-basin number 3 has the highest flood impact with 14,699 hectares and sub-basin number 5 has the lowest total flood impact of 968.82 hectare.
Effect of Adding Probiotic Yeast and Fermentation Time on Probiotic Tempeh Characteristics
Authors: Qibty Mari'ah , Yulianto Wisnu Adi , Pujimulyani Dwiyati
Published: October 2024

Tempeh is one of the foods made from soybean seeds or other ingredients that are processed through fermentation. Tempeh currently circulating in the community does not contain probiotic yeast, the addition of probiotic yeast is intended to provide probiotic properties to tempeh. From previous studies, yeast isolates from radishes and tomatoes have been identified as potential probiotic yeasts. This study aimed to determine the effect of adding the type of probiotic yeast isolate and fermentation time on the number of fungi, the number of yeasts, pH, antioxidant activity, and the level of preference by panelists for the resulting probiotic tempeh. This study used a completely randomized design with a factorial pattern. The first factor was the type of probiotic inoculum (Saccharomyces boulardii, yeast isolate LBK K, yeast isolate TMT 2), and the second factor was incubation time (0 hours, 24 hours, and 48 hours). The analysis included the number of fungus and yeast (plate count agar), antioxidant activity (radical scavenging activity (%), and preference level for probiotic tempeh. The data obtained were analyzed for variance (ANOVA) at a 95% confidence level. If there was a significant difference between each treatment was continued with Duncan's multiple range test (DMRT). The results showed that adding probiotic yeast type and a long incubation time affected the microbiological properties, antioxidant activity, and panelist preference. The most preferred tempeh was tempeh with the addition of LBK K isolate with an incubation time of 48 hours with a pH of 5.46, the total number of fungi was 6.62 log CFU/g, the total amount of yeast was 8,63 log CFU/g, the antioxidant activity was 18.58% RSA. Tempeh, with the addition of LBK K yeast isolate, has the potential as a probiotic food.
Pengaruh Konsentrasi ZnCl2 dan Metode Pemanasan terhadap Karakteristik Serbuk Simplisia Sambiloto (Andrographis paniculata)
Authors: Suryani Lilis , Putra Danis Aprianto , Fitri Ichlasia Ainul
Published: October 2024

Proses pemanasan dalam pembuatan simplisia sambiloto mengakibatkan degradasi klorofil. Peningkatan stabilitas klorofil dapat dilakukan dengan pembentukan kompleks mettaloklorofil dengan logam yang lebih stabil seperti Zn. Keberhasilan pembentukan Zn-klorofil juga dipengaruhi oleh metode pemanasan, diketahui proses blanching mengakibatkan banyak klorofil yang terlarut dalam medium, sehingga dalam penelitian ini digunakan metode pemanasan oven dan autoklaf. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi reagen ZnCl2 dan metode pemanasan terhadap karakteristik kimia, dan fisik bubuk simplisia sambiloto yang dihasilkan.
Cara pembuatan simplisia sambiloto dilakukan melalui tahapan sortasi, penggilingan, pengayakan, pencampuran dengan ZnCl2 (0, 200, 300, 400, dan 500 ppm), pemanasan (oven dan autoklaf), dan pengeringan. Bubuk simplisia sambiloto yang dihasilkan dianalisis kadar air, kadar abu, kadar klorofil, warna dan stabilitas warnanya. Rancangan yang digunakan dalam penelitian ini adalah Rancangan Acak Kelompok (RAK) dengan 2 faktor. Data yang diperoleh dianalisis variansi dan jika berpengaruh nyata dilanjutkan dengan DMRT.
Hasil penelitian menunjukkan bahwa variasi metode pemanasan dan konsentrasi ZnCl2 berpengaruh nyata terhadap kadar abu, klorofil, intensitas warna hijau, dan stabilitas warna, namun tidak berpengaruh nyata terhadap kadar air bubuk simplisia sambiloto. Bubuk simplisia sambiloto yang berkadar klorofil tinggi dapat dihasilkan dengan konsentrasi reagen ZnCl2 200 ppm dan metode pemanasan dengan autoklaf dan mempunyai kadar klorofil 420.94 mg/100 g bb, kadar air 7.13 % bb, kadar abu 15.41 % bk, dan intensitas warna hijau -2,58.
Pengaruh Penambahan Ekstrak Kulit Buah Naga Merah dan Variasi Konsentrasi Starter Terhadap Karakteristik Soygurt
Authors: Kartikaningrum Ayu Rara , Setiyoko Agus , Slamet Agus
Published: October 2024

Soygurt adalah produk dari hasil fermentasi susu kedelai menggunakan bakteri asam laktat. Salah satu faktor penting yang menentukan kualitas soygurt adalah konsentrasi starter. Kulit buah naga merah (Hylocereus polyrhizus) mengandung senyawa antioksidan yang lebih besar dibandingkan daging buahnya. Tujuan dari penelitian ini adalah untuk menghasilkan soygurt yang ditambah ekstrak kulit buah naga merah dengan sifat fisik dan kimia yang disukai oleh panelis serta mengandung antioksidan. Metode yang digunakan adalah penelitian eksperimen dengan Rancangan Acak Lengkap (RAL) dengan dua faktor yaitu konsentrasi penambahan ekstrak kulit buah naga merah 0%, 2%, 4%, 8% dan variasi konsentrasi starter yaitu Lactobacillus bulgaricus, Streptococcus thermophilus, dan Lactobacillus acidophilus (1:1:1) 5% dan 7%. Sifat-sifat yang dianalisa meliputi nilai warna L*a*b*, pH, viskositas, dan tingkat kesukaan panelis pada semua perlakuan dan kadar abu, kadar protein, total asam laktat, dan aktivitas antioksidan pada perlakuan terbaik. Hasil penelitian menunjukkan penambahan ekstrak kulit buah naga merah pada level tertentu dan konsentrasi starter berpengaruh nyata terhadap sifat fisik (nilai L*, nilai a*, viskositas, pH) dan tingkat kesukaan panelis terhadap terhadap penampakan, warna, aroma, rasa, dan penerimaan secara keseluruhan. Soygurt dengan penambahan ekstrak kulit buah naga 4% dan starter sebanyak 5% merupakan produk yang paling disukai oleh panelis dan memiliki nilai warna L* 64,28; nilai warna a* 6,83; nilai warna b* 13,15; pH 4,41; viskositas sebesar 111,46 cP; dan aktivitas antioksidan 29,67 %RSA dengan kadar abu 0,58 %bb; kadar protein 3,64 %bb; keasaman 1,23% yang telah sesuai SNI.
THE IMPORTANCE OF THE SPECTROPHOTOMETRIC ANALYSIS METHOD IN THE STUDY OF THE COMPOSITION OF SUBSTANCES
Authors: Ibodulloeva M.I  , Misirova Z.M.
Published: October 2024

This article discusses the importance of the spectrophotometric analysis method, one of the physico-chemical analyses, for studying the composition of substances.
School Leaders Promoting Teachers’ Wellness: A Lebanese Case Study
Authors:   ,   Lebanese American University -- Chouran Beirut, Nassereddine Sana
Published: October 2024

Lebanon is facing a lot of challenges including the aftermath of the COVID-19 pandemic and Beirut’s massive explosion, political impasse and growing conflict, economic downturn, the current war and many more. These challenges are affecting everyone including teachers’ wellness. This is an issue because teachers’ wellbeing not only affects teachers, but everyone involved in the educational system, from leaders and principals all the way down to individual students. This brings attention to the fact that wellness is crucial; hence, it should be prioritized and supported. Therefore, the aim of this study is to investigate the factors influencing teachers’ wellness and examine how these factors impact the school’s practices to promote teachers’ wellness under a transformational leadership style. To achieve this, I conducted an exploratory case study in a typical middle-class Lebanese private school located in south Lebanon. Using a mixed-methods approach encompassing quantitative and qualitative methods including observations, document analysis, interviews, and questionnaire, the study identified eight main themes aligning with the dimensions of teachers’ wellness. These dimensions include physical, emotional, social, environmental, occupational, intellectual, financial, and spiritual wellness. The qualitative data revealed 63 practices undertaken by the school to foster teachers’ wellness during times of crises. As for quantitative analysis, the statistical data of 89 teachers’ responses unveiled a strong correlation among almost all practices across the various dimensions of teachers’ wellness. Notably, these practices were mostly focused on fostering teachers’ job satisfaction. The practical strategies identified for promoting teachers’ wellness during crises can enhance leadership approaches, empowering educators to navigate challenges effectively. Prioritizing teachers’ wellness based on these findings can create a nurturing environment that benefits both teachers and students, fostering a culture of wellness within educational communities.
Culturas políticas de las emergentes capas medias cubanas
Authors: Gamez Irenia , Hernández Castro Hiriam
Published: October 2024

¿Cómo están navegando las emergentes capas medias cubanas las intrincadas realidades de una sociedad marcada tanto por aspiraciones democratizadoras como por desigualdades crecientes? Este artículo busca responder a esta pregunta, poniendo bajo el lente las experiencias y perspectivas de los individuos que han hallado oportunidades en el negocio del arrendamiento turístico internacional en La Habana. Dando una mirada a las transformaciones post-90, el estudio explora cómo estos cambios han influenciado y, a la vez, han sido reflejados en las culturas políticas de las capas medias emergentes. Se trata de una discusión que no solo destaca lo nuevo, sino que también rescata elementos persistentes en el tejido cultural y político cubano.
Em defesa da nação e da moralização da política
Authors: Salomão Arthur
Published: October 2024

O objetivo geral deste artigo consiste em analisar o protagonismo da altaclasse média brasileira nas manifestações pelo impeachment de Dilma Rousseff (2015-16). Partindo da literatura que identifica uma presença sobrerepresentada dessa camada social na campanha pró-impeachment, nossos objetos são, mais especificamente, os interesses de classe e a matriz ideológica que significou o discurso das manifestações pelo impeachment. Para isso, discutimos inicialmente o papel decisivo da alta classe média na conformação da oposição ao lulismo e as motivações de sua revolta contra as políticas neodesenvolvimentistas dos governos do PT. Em seguida, analisando os dados sobre a composição social dos protestos e o discurso dos manifestantes expresso em cartazes e palavras de ordem, procuramos sustentar que três elementos ideológicos organizaram os manifestantes e significaram as mobilizações hegemonizadas pela alta classe média: o antipetismo, a luta contra a corrupção e o nacionalismo lavajatista. Por consequência, sustentamos que, naquele contexto particular, a alta classe média, insatisfeita com a postura dos tucanos na crise, encontrou sua representação política na Operação Lava Jato e o lavajatismo encarnou o “partido” em defesa do Brasil.
The Nutritional Status of Breastfeeding Mothers and Breastfeeding Adequacy in Indonesia: A Systematic Review
Authors: Rachmadiani Ainindya Pasca , Nadhiroh Siti Rahayu
Published: October 2024

Background: One of the basic capitals for the formation of quality human beings is the consump­tion of breast milk. The amount of breast milk produced is highly dependent on the mother's diet. This study aimed to identify the relationship between the nutritional status of breastfeeding mothers and breast milk adequacy in Indonesia.
Subjects and Method: This was a systematic review using PICO model to formulate the research question. Population= breastfeeding mothers. Intervention= adequate BMI and MUAC. Comparation= poor BMI and MUAC. Outcome= breast milk adequacy. The database used is Google Scholar with keywords “Anthropometry” OR “BMI” OR “Breastfeeding mothers” OR “breast milk adequacy” OR “Indonesia”. There were 10 cross-sectional studies and 2 cohort studies published in 2011-2023 that met the inclusion criteria.
Results: There is mostly a relationship between the nutritional status of breastfeeding mothers as measured by BMI and MUAC with the adequacy of breast milk.
Conclusion: The adequacy of breast milk can be influenced by the nutritional status of the mother while breastfeeding. The nutritional status of breastfeeding mothers is no less important than the nutritional status of pregnant women so that risks such as stunting do not occur.
Dynamics and prognostic repeatability of qualitative and quantitative blood characteristics in patients with new coronavirus infection
Authors: Slesareva T. A. , Kuzmina A. A. , Alekseenko A. V. , Tarasova O. L. , Dyleva Yu. A. , Belik E. V. , Uchasova E. G. , Bazdyrev E. D. , Hoffman L. S. , Gruzdeva O. V.
Published: October 2024

The study presents the possibility of using clinical blood test indicators characterizing the red hematopoietic germ in diagnosing the severity of the clinical condition of patients with COVID-19.

Aim: Dynamic monitoring of changes in the quantitative and qualitative characteristics of erythrocytes and reticulocytes to identify parameters that characterize the severe course of a new coronavirus infection in patients with cardiovascular pathology.

Material and Methods. The study included 94 patients with a confirmed diagnosis of a novel coronavirus infection (NCI), hospitalized in the department for the treatment of patients with CVD and COVID-19 with intensive care unit on the basis of the Academician L.S. Barbarasha between February and March 2022. Clinical blood analysis was performed on the 1st, 3rd and 7th day of hospitalization. Whole blood with K2EDTA was studied on a Sysmex XN-1000 hematological analyzer.

Results. To determine the diagnostically significant indicators of a clinical blood test, patients were divided into 2 comparison groups: group 1 – 71 people with a mild infection, group 2 – 23 people with moderate, severe and extremely severe NCI. On the first day of observation, 70% of patients in the group of unfavorable course were diagnosed with anemia, while in the group of mild course, 38% of patients were diagnosed. In patients with unfavorable development of the disease, normoblastemia was observed, which, according to the results of regression analysis, increased the risk of an unfavorable course by 5 times OR 0.24 (95% CI 0.07–0.884). Also in the severe group, there was a decrease in hemoglobin saturation of reticulocytes, which was expressed in deficient Ret-He and negative Delta-Hb values. Using binary logistic regression, it was found that a negative Delta-Hb 6 times increases the risk of an unfavorable course of NCI, OR 6.18 (95% CI 1.971–19.3).

Conclusion. The parameters of a clinical blood test that characterize the hemoglobinization of reticulocytes reflect the severity of the course of a new coronavirus infection and can be used to assess the clinical condition of patients with this infection.
The effect of chronic predatory stress on the histostructure of the rat liver
Authors: Andreeva I. V. , Vinogradov A. A. , Simakov R. Yu. , Natalskiy A. A. , Turkova M. A.
Published: October 2024

One of the topical issues of modern circulatory physiology is the study of the peculiarities of the influence of chronic emotional stress on the histostructure of the liver.

Aim: To study changes in the histostructure of the liver in the simulation of chronic predatory stress.

Methodology and Research Methods. The study was conducted on 60 male Wistar rats weighing 220–370 g, divided into control and experimental groups of 30 rats each. Modeling of chronic predatory stress was performed according to the method of V.E. Zeilikman et al. (2021). Histological examination of the liver was performed in animals of the control and experimental groups. The preparations were stained with hematoxylin-eosin.

Results. Under conditions of chronic predatory stress, stress-induced changes develop in the liver of rats. Transformation of hepatocytes occurs with the development of dystrophic changes, expansion and fullness of sinusoidal capillaries with compression of hepatic beams and destruction of hepatic lobules, a decrease in the parenchymal-stromal ratio. Foci of foamy accumulation of macrophages appear without signs of necrosis, single or group apoptotic hepatocytes. Necrotic foci are formed. The number of Kupffer cells and binucleated hepatocytes increases.

Conclusion. With chronic predatory stress, the processes of dystrophy, necrosis and apoptosis of hepatocytes, signs of phagocytosis and regenerative processes, and decreased immune protection develop in the liver of rats.
Effect of hydrocortisone on the course of leprosic infection in an experiment
Authors: Gennatulina G. N. , Saroyants L. V.
Published: October 2024

Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae), accompanied by a violation of various parts of the immune system. In this regard, the development of an experimental model of leprosy may be based on the creation of an artificial defect of the macrophage link, in particular, using glucocorticoids. 

Aim: To develop and characterize a model of generalized leprosy infection in mice against the background of prolonged administration of hydrocortisone.

Material and methods. To conduct the study, the following groups were formed: the control group – 50 mice infected by the Shepard method; the experimental group – 50 mice similarly infected against the background of hydrocortisone administration. Hydrocortisone was administered intramuscularly in a single daily dose of 25 mg/kg on the first day 2 hours before infection with M. leprae suspension, then in the form of four courses of 2 weeks at two-week intervals.

Results. The administration of hydrocortisone led to an acceleration of the reproduction of mycobacteria in the paw pad compared with the control (without hydrocortisone). The generalization of leprosy infection is confirmed by the presence of lepromatous structures in the form of granulomas from macrophages with a high content of M. leprae in liver, spleen, lungs and kidneys.

Conclusion. This model allows us to study the properties of the pathogen and the mechanisms of pathogenesis of the disease, and to screen pharmacological drugs with potential anti-leprosy activity in the future.
Sample size for assessing a diagnostic accuracy of AI-based software in radiology
Authors: Bobrovskaya T. M. , Vasilev Yu. A. , Nikitin N. Yu. , Vladzimirskyy A. V. , Omelyanskaya O. V. , Chetverikov S. F. , Arzamasov K. M.
Published: October 2024

Introduction. Determining the minimum sample size for solving various tasks is an extremely important and at the same time unexplored problem. There are many methods, but most of them are not applicable for AI-based software validation.

Aim: To consider a methodology for determining a balance of classes “norm”/ “abnormality” and propose a statistical approach to determine the data amount necessary for testing AI-based software (validation).

Material and Methods. The results of AI-based software were analyzed using dataset of mammograms. Mammograms were classified by the presence of breast cancer (“abnormality”) and the absence of breast cancer (“norm”). The general set contains 123,301 unique studies. The original balance of classes in the study was “norm” 89.3%/“abnormality” 10.7%. As the results of AI-based software (ML-algorithm), a probability of the presence of pathology in the entire study was taken. The following values were used as empirical data (GT): 0 – in case of Bi-RADS classes 1 or 2 diagnosed by a doctor, and 1 – in case of Bi-RADS classes 3, 4, 5. Each data sample is transferred to AI-based software for processing. Quality metrics are calculated based on its results: AUC ROC. All the described actions were repeated 10,000 times for all the studied balances of “norm”/”abnormality”. Based on the results of AUC ROC calculations, mean values were calculated for different random data series with the same balances. Mean AUC ROC values were subjected to analysis.

Results. A maximum value of the coefficient of variation of AUC ROC values for 10% “abnormality” share is achieved at the number of studies equal to 190; for the 20% share, it is 80 studies; for the 30% share – 120 studies, for the 40% share – 110 studies, and for the 50% share – 70 studies.

Conclusion. Summarizing the conducted study results, it can be concluded that when testing AI-based software, it is necessary to consider that the number of studies reflecting the greatest heterogeneity of AUC ROC values (the largest deviation from the mean value) is different for various class balances. If the purpose of validation is to establish the worst-case behavior of AUC ROC values, then for the studied AI-based software, the “abnormality” share should be 10%, and the number of studies 190. If the validation is carried out under conditions of a limited amount of data, then the “abnormality” share should be 50% and the number of studies equal to 70.
Clinical and dynamic features of bipolar affective disorder in patients with chronic coronary artery disease
Authors: Lebedeva E. V. , Schastnyy E. D. , Simutkin G. G. , Nonka T. G. , Vasilieva S. N. , Repin A. N.
Published: October 2024

Introduction. Currently, the study of comorbidity, which is characteristic of the clinical picture of modern patients, is relevant. This also applies to psychiatric disorders in cardiovascular diseases, which are common, affect social functioning and determine the clinical and biological characteristics of patients and prognosis. Bipolar disorder and coronary heart disease are one example of such a comorbidity. Recent evidence suggests that up to 40% of patients with bipolar disorder die from cardiovascular disease.

Aim: To study the frequency of bipolar disorders and their clinical and dynamic features in patients with chronic coronary artery disease with the assessment of seven-year survival rates.

Material and Methods. Patients with confirmed chronic coronary artery disease, aged 35–70 years, living in Tomsk and the Tomsk Region: the main group (with identified mood disorders, diagnosed by a psychiatrist, n = 262) and the comparison group (without mood or other mental disorders, n = 291). The Hamilton Depression Scale for Seasonal Affective Disorders was used to assess depressive symptoms. The survival tables and Kaplan – Meier methods were used to assess survival, survival curves were compared using the Mantel – Cox logrank test.

Results. The frequency of bipolar disorder among hospitalized patients with chronic coronary artery disease was three times higher than that in the population. Depressive symptoms in bipolar disorder did not differ clinically from those in other mood disorders. The prognostic signs indicating the risk of bipolar disorder include: family history with mental disorders, atypical specification of depression, earlier age of onset of depression, high multimorbidity with mental (anxiety disorders, dependence syndrome due to alcohol, nicotine) and physical diseases. According to a retrospective assessment, coronary artery disease in half of the cases developed against the background of bipolar disorder. During the 7-year follow-up period, the number of cases of bipolar disorder doubled compared to the beginning of the study. Patients with bipolar disorder had more frequent acute myocardial infarction and had clinically more significant functional classes of angina pectoris and heart failure.

Conclusion. During the 7-year follow-up period, the number of patients with bipolar disorder doubled. Patients with this comorbidity had an unfavorable prognosis in terms of survival (62.5%) compared with individuals without mood disorders.
Towards a Theory of Emotional Autonomy
Authors: White Tony
Published: October 2024

The author challenges the emotional contagion theory and proposes an alternative of emotional autonomy. He critiques how the contagion theory is faulty logic because it assumes different individuals may experience identical emotions, rather than each having their own phenomenological experience even though the outward signs may look similar. A way of ascertaining individual experiences of emotions is suggested, followed by an example of the experiences of pain, before the conclusion that we should adopt within the literature the assumptions of emotional autonomy.
Transactional Analysis Proficiency Awards for Adolescents
Authors: Connors Sam
Published: October 2024

A comprehensive review of how adolescence is a period of major transition is followed by the suggestion that a transactional analysis programme that has been running internationally for several years might usefully be introduced into UK schools, and readers are invited to become involved.
A STUDY OF INTERNET ADDICTION AMONG ADOLESCENTS AND THEIR BEHAVIOURAL PATTERNS
Authors: Azeem Md Aman , Md Fahimuddin , Vali Karanam Mahaboob
Published: October 2024

This study aims to explore the phenomenon of internet addiction among adolescents and their behavioural patterns. Data for the study was gathered through in-depth interviews with five hundred seventy children, ages twelve to seventeen, who reported excessive internet use and its detrimental effects. The research design utilised in the study was qualitative. The data was analysed using the thematic analysis method to find themes and patterns about internet addiction and how it affects children's behaviour. The results showed that internet addiction among children in India is a growing concern and affects their behaviour patterns in several ways, including neglect of studies and physical activity, social isolation, anger issues, frustration, lack of respect towards elders, unrealistic dreams and demands, cyberbullying, and risky online behaviour, etc. The findings suggest increased awareness and education about the dangers of excessive internet use and support for adolescents and their families.
WATER QUALITY OF YAMUNA RIVER AT PRAYAGRAJ, U.P., INDIA
Authors: Nath Satyendra , Pandey Jigyasa , Nath Shailendra , Sam Sapna , Masih Shalini
Published: October 2024

Rivers are an essential part of our biosphere which is essential for the overall development of the present civilization. The present study was carried out to analyze the water quality at selected sites of river Yamuna in Prayagraj (Allahabad) city during January 2019 to May 2019. Samples were collected and analyzed for assessing the water quality characteristics as pH, turbidity, alkalinity, Ca 2+ hardness, Mg 2+ hardness, Cl- and Sulpate. The obtained results were compared to the standards limits of BIS. Analysis results showed that pH, turbidity, alkalinity, sulphate, Chloride of water was found within the permissible limits while Calcium and magnesium hardness values are higher than the permissible limits of BIS standards. The possible causes of deteriorating of Yamuna water due to discharged of untreated water and other human activity.
INTRANSIGENCE AND SELF-IDENTITY IN NAVARIA'S NEW CUSTOM
Authors: M. Ramalingam  , Dr. N. Ranjithkumar  , Dr. S. Ramanathan
Published: October 2024

The shot story New Custom crystal clearly expose the prevailing caste system in ourcountry. Though everything may change, the caste system in India will never change. Ever if our India become a developed country, it is hard for our people to get away from this ridiculous practice of casteism. Ajay Navaria has beautifully brings about that no one can erase casteism from the mind of people, such as the people of Rajgarh in the story New Custom. Action that are taken to prevent casteism remains only a printed text , it doesnt come into practice and it won’t unless the antibiotic enters in, which is education. Well educated and scholarly men will never think of it.thats how the protagonist of this short story be like. He has been portrayed as a pure, and good hearted soul .it is true that unless we change the belief, we could not change ones character. The belief of a person can be changed only by Education. Education is the ligh ,which eliminate the darkness which abound the society.
ADVANCED TECHNIQUES IN MULTI-LABEL TEXT CLASSIFICATION: INTEGRATION OF BETA ANT COLONY AND DEEP LEARNING APPROACHES
Authors: Shrivastava Amit , Rakesh Kumar
Published: October 2024

The rapid growth of unstructured textual data in various domains has necessitated the development of sophisticated techniques for multi-label text classification. Traditional methods often struggle with handling the complexity and interdependence of multiple labels, leading to suboptimal performance. This paper presents an advanced approach that integrates the Beta Ant Colony Optimization (BACO) algorithm with deep learning techniques for multi-label text classification. The BACO algorithm effectively explores the feature space and selects relevant features by leveraging pheromone trails, while the deep learning model captures intricate patterns and relationships within the textual data. The integration of these two methodologies aims to enhance the efficiency and accuracy of multi-label classification tasks, particularly in domains where label dependency is prominent. Empirical evaluations on benchmark datasets demonstrate that the proposed hybrid approach outperforms existing state-of-the-art techniques in terms of precision, recall, F1-score, and computational efficiency. The findings suggest that combining heuristic optimization algorithms with deep learning can significantly improve multi-label text classification performance, providing a robust solution for real-world applications.
Introduction to Interactive Video-Based E-Learning to Improve Critical Thinking Skills in Vocational High School Students
Authors: Irwan Irwan
Published: October 2024

This Community Service (PKM) activity aims to introduce interactive video-based e-learning to improve critical thinking skills in Vocational High School (SMK) students. Critical thinking skills are essential in facing the challenges of the world of work, especially for vocational school graduates. This activity was conducted online through the Zoom application, involving vocational school teachers as the main participants. The training focuses on using interactive videos as a learning medium that integrates interactive elements such as reflective questions, simulations, and problem-solving tasks to stimulate active student engagement. The evaluation was carried out through pre-test and post-test tests that showed a significant improvement in students' critical thinking skills, with an average post-test score of 80, an increase from 65 in the pre-test. In addition, a survey of teachers showed that 85% of participants benefited from using interactive videos to make learning more engaging and effective. However, some challenges related to internet infrastructure and students' technical ability to access video were identified. As a solution, materials are also provided offline. The results of this activity show that interactive video-based e-learning effectively improves the critical thinking skills of vocational school students. Hopefully, this method can be adapted more widely in the context of vocational education and contribute to developing the quality of education in Indonesia.
Artificial intelligence (AI) in Medicine: A cross-sectional study of undergraduate medical students’ knowledge, attitudes, and perceived importance of Artificial Intelligence.
Authors: Muhammad Abdullah  , Hamza Khaliq  , Yasir Yaqoob  , Menahal  , Sameen Rafique  , Pakeeza Naeem
Published: October 2024

Objective: To assess the knowledge and perceptions of AI among medical students in a public sector medical college of Punjab, Pakistan. Study Design: Cross-sectional study. Period: January 2024 to March 2024. Methods: With sample size of 137 convenient sampling technique was used, questionnaire was generated and data was collected from 1st year to final year via online Google forms. Then, data analysis was done using IBM SPSS software version 26. Results: 137 students participated in the study. Majority of the students 123(89.8%) were aware of Artificial Intelligence and its fascinating tools; some out of them 57(41.6%) also knew about Machine Learning & Deep learning and their applications in medical field 87(63.5%). Some of them 44(33.6%) believed that AI will be a burden on medical practitioners but majority 107(78.1%) of the students are willing to work on AI. Conclusion: Many students knew much about AI and they had good perception regarding AI functioning in the medical field. They are keen to master the skills of AI and they are looking forward to utilize these tools in their medical studies as well as during healthcare practice.
ORIENTAÇÃO SEXUAL PARA PAIS DE PESSOAS COM DEFICIÊNCIA
Authors: Costa Filho José Andrade , Balbino Luan de Sousa , Sá Izabela Cristina Alves Soares
Published: October 2024

A literatura científica registra a sexualidade de forma ampla, difusa e histórica, uma vez
que ela se manifesta na sua dimensão total, abarcando as esferas biológica, psicológica e social.
Nessa perspectiva, a sexualidade não se limita ao prazer sexual, mas se manifesta sobretudo
pelo toque e em todas as formas de expressão de afeto. Ao abordar esse tema, percebe-se que o
exercício do papel sexual e afetivo da pessoa com deficiência é negligenciado ou esquecido, em
detrimento de mitos e preconceitos produzidos pela cultura e transmitidos, principalmente, pela
família, erguendo barreiras atitudinais e impedindo a vivência íntegra dessas pessoas. Nesse
sentido, este trabalho classifica-se como estudo descritivo, com o modelo de relato de experiência, vivenciado por um grupo de estudantes de psicologia da Universidade Estadual da Paraíba,
no projeto de extensão Orientação Sexual para Pais de Pessoas com Deficiência, financiado
pela UEPB na cota 2022/23. As intervenções realizadas tiveram como objetivo geral orientar
os responsáveis de PcDs no que concerne à dimensão da sexualidade, bem como a produção de
estratégias ao abordar esse assunto no contexto familiar. Por sua vez, o público-alvo das ações
se concentrou na Associação de Pais e Amigos dos Excepcionais de Campina Grande, Paraíba
– APAE CG. A metodologia foi pensada sob um viés de acolhimento e executada a partir de 7
rodas de conversa, com temáticas e dinâmicas semi-estruturadas, que ganharam forma a partir
das demandas relatadas pelos participantes. A partir deste trabalho foi possível promover o entendimento dos pais sobre a sexualidad
POLÍTICAS PÚBLICAS E SUSTENTABILIDADE: A gestão do meio ambiente e o desafio na sociedade contemporânea
Authors: Moreira Bruna Silva dos Santos
Published: October 2024

RESUMO
Esta pesquisa tem por objetivo discorrer sobre as políticas públicas e gestão de sustentabilidade do meio ambiente no desafio enfrentado pela sociedade contemporânea. Foi desenvolvido um estudo qualitativo, descritivo e bibliográfico. A relação entre gestão pública e desenvolvimento sustentável tem sido estudada em profundidade através de uma revisão da literatura global. Os resultados revelaram como a gestão pública está ligada aos objetivos de desenvolvimento sustentável como a previsão, a estratégia e a institucionalização, juntamente com a monitorização. Concluiu-se que o enfoque na gestão pública e na sua integração com o desenvolvimento sustentável é crucial para o funcionamento eficaz das instituições governamentais, com ênfase no planejamento, controle e execução adequados, bem como na manutenção sustentável dos serviços públicos e na administração eficiente dos recursos econômicos.
Palavras-chave: Políticas Públicas. Sustentabilidade. Gestão.
ANÁLISE CRÍTICA DO FORNECIMENTO DE MEDICAMENTOS PELO PODER PÚBLICO: UM ENFOQUE SOBRETUDO JUDICIAL
Authors: Santos Luiz Henrique Alves
Published: October 2024

O direito à saúde no ordenamento jurídico brasileiro está previsto no artigo 196 da Constituição Federal e é uma parte intrínseca ao bom funcionamento da sociedade. Trata-se de uma garantia universal e uma extensão do direito à vida. Ocorre que devido às limitações orçamentárias e ao quadro de insegurança jurídica – o que se tem, na realidade, é o descumprimento de preceitos fundamentais elencados na própria Constituição Federal. Com efeito, os tribunais superiores brasileiros procuram afastar este cenário de insegurança jurídica, uniformizando entendimentos quanto a responsabilidade de cada ente federativa no fornecimento de medicamentos, esclarecendo os limites de competência para cada um, bem como traçando uma linha consciente da separação dos poderes. Em seu agir, fixam teses de repercussão geral e informativos jurisprudenciais quanto a concessão de medicamentos não padronizados, aqueles representados pelo termo “off-label” e os de uso experimental. O que motivou o início da pesquisa foram as observações empíricas do pesquisador, notadamente pelo seu período de atuação no Poder Judiciário Brasileiro. Por essa via, então, o presente estudo tem como objetivo o estudo do fornecimento de medicamentos no âmbito judicial e o papel do Estado. Para a construção metodológica do trabalho, foi utilizada uma abordagem qualitativa, com busca doutrinária e de artigos científicos, centralizada na análise jurisprudencial sobre o tema abordado
A Carta de Direitos Fundamentais e a jurisprudência do Tribunal de Justiça da União Europeia sobre trabalhadores migrantes deslocados
Authors: Saldanha Jânia
Published: October 2024

Resumo: A Carta de Direitos Fundamentais da União Europeia (CDFUE) constitui um importante avanço histórico da proteção dos direitos humanos, a qual consolidou e ressaltou a evolução desses direitos ao longo do tempo e a universa
lidade dos valores compartilhados pela humanidade.
Los Derechos del Consumidor y los Derechos Humanos: una especial referencia a la Carta de Derechos Fundamentales de la Unión Europea y a la Constitución Nacional de los Estados Latinoamericanos
Authors: Labrano Roberto Ruiz Díaz
Published: October 2024

Resumen: Los derechos del consumidor, al igual que los derechos humanos, tuvieron origen en la necesidad de hacer valer el respeto a la persona frente al creciente poder del Estado y del mercado, en la creencia efectiva y con base fáctica que, de no oponerse derechos fundamentales a esos factores de poder, la debilidad del ciudada no aislado se transforma en indefensión y abandono. Al igual que en los derechos
humanos, los derechos del consumidor asumen carácter transversal, por cuanto sus
disposiciones de protección son en general comunes a las reconocidas por todos los Estados. Tanto los derechos humanos como los derechos del consumidor forman
parte esencial de la protección de la vida y actividad de las personas en su vida en la sociedad y en sus derechos económicos. Los derechos del consumidor tienen su pro
pia dinámica, conforme la evolución de los bienes y servicios de los que se sirve, por lo cual su protección debe evolucionar y adaptarse a las nuevas realidades como los desafíos que representan las nuevas tecnologías que son puestas a su alcance.
Palabras claves: Derechos del Consumidor. Derechos Humanos. Carta de Derechos Fundamentales de la Unión Europea.
Penerapan Digital Marketing sebagai Upaya Peningkatan UMKM Keripik Pepaya di Desa Lubuk Enau
Authors: Zafitry Herlin , Triyani Nina Eka , Aziz Muhammad Ichsan , Hildayanti Siti Komariah , Pebriani Reny Aziatul , Kospa Herda Sabriyah Dara
Published: October 2024

The ever-evolving technological transformation can produce innovations that attract public attention over time. Digital marketing is a form of effort that uses digital media, such as the internet, to promote and market a brand. However, the lack of understanding of village communities regarding sales in the market is a problem that needs to be understood. Lubuk Enau Village is a place for community service activities. This social service activity was carried out by KKN-Thematic students of the Faculty of Economics, Universitas Indo Global Mandiri, in the context of Sustainable Entrepreneurship Development Efforts in Lubuk Enau Village. This guidance is expected to make it easier for MSME economic actors to create a marketplace that aims to sell processed culinary products such as Instagram, Facebook, WhatsApp, and other e-commerce. Increasing online sales promotions aims to expand the marketing of papaya chips so that it can increase the economy of business actors.
Perbaikan Aspek Produksi, Manajemen dan Hukum Kelompok UMKM “Tuty Collections”
Authors: Saefullah Encep , Mukhlis Ahmad , Hifni Mohammad
Published: October 2024

Permasalahan mitra sasaran kelompok UMKM “Tuty Collections” meliputi proses produksi masih dikerjakan secara manual, sehingga produk yang dihasilkan belum terstandarisasi, desain dan model produk belum banyak variasi, jumlah mesin jahit yang dimiliki masih kurang, sehingga mempengaruhi jumlah produksi yang dihasilkan, pengetahuan dan keterampilan SDM mitra dalam pengelolaan usaha masih minim, belum memiliki legalitas operasional usaha, keterampilan mitra dalam pemasaran masih minim dan metode penjualan masih secara konvensional, belum menggunakan media digital, sehingga volume penjualan sulit naik. Dengan menggunakan metode kronologis, pelaksanaan kegiatan ini menghasilkan peningkatan jumlah produksi dan penjualan produk mitra sebesar 75% dan diperolehnya legalitas hukum operasional usaha dalam bentuk NIB.
Pelatihan Pembelajaran Numerasi Berdiferensiasi Menggunakan Media Digital bagi Guru Sekolah Dasar Luar Biasa (SDLB)
Authors: Lutfianto Moch. , Lestariningsih Lestariningsih , Hartanto Wido
Published: October 2024

The challenges faced by teachers, ranging from the diverse cognitive abilities of each student to unique learning styles, cause the numeracy learning process in Special Elementary Schools (SDLB) to become increasingly complex. Meanwhile, several studies and discussion results show that teachers' ability to design differentiated numeracy learning using digital media is still low. Hence, community service was carried out with the aim of developing the abilities of SDLB teachers in designing differentiated numeracy learning using digital media for teachers at SDLB Muhammadiyah in Gresik. Service activities start from preparation, socialization, training, application of technology, to mentoring and evaluation. The training activity was carried out for three days at school, and at the end of the activity, participants were asked to fill out an activity questionnaire. Based on the results of activity questionnaires and interviews with teachers, it can be seen that teachers' knowledge in differentiated numeracy learning is developing well. They design differentiated learning based on the results of the initial assessment given to students. Furthermore, teachers' skills in using digital media have also increased. Therefore, we can conclude that this service activity can enhance teachers' skills in designing differentiated numeracy learning through the use of 3D flipbook digital media.
Strategi Pemasaran Inovatif untuk Menarik Wisatawan ke Wisata Pemandian Jang Oden
Authors: Pamukti Hakiki , Sari Lilis Permata , Rossi Lola Valentina , Saputri Selfi , Gumano Hendry Natanael , Purnamasari Endah Dewi , Anggraini Leriza Desitama
Published: October 2024

Salah satu desa yang memiliki potensi wisata di Kabupaten Lembak adalah Desa Kemang. Wisata Pemandian Jang Oden merupakan destinasi wisata dengan keindahan alam yang unik, namun karena kurangnya pemasaran sehingga kurang diketahui banyak wisatawan.Oleh karena itu, strategi pemasaran yang inovatif perlu diperkenalkan untuk meningkatkan kunjungan wisatawan. Metodologi yang digunakan dalam kegiatan ini adalah pendekatan partisipatif dan penerapan strategi pemasaran inovatif yang efektif. dilakukan melalui penggunaan media sosial seperti Instagram untuk mempromosikan destinasi wisata tersebut. Pemasaran Google Maps juga digunakan untuk meningkatkan aksesibilitas. Paket promosi refreshing dilengkapi fasilitas karaoke gratis dapat menjadi daya tarik tambahan. Hasil dari pengabdian ini berdampak positif setelah dilakukan pemasaran di Instagram, menunjukkan bahwa strategi ini efektif dalam meningkatkan kesadaran dan kunjungan wisatawan ke destinasi wisata ini.