bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case of Intracranial Space-occupying Lesion Caused by Infection of
AIDS-associated Talaromyces Marnefei
Authors: Tang Xiaoping , Liu Jinxin , Xie Shuyi , Zhang Lieguang , Huang Deyang , Yang Yanhong , Zhang Zhiping , Xiao Yanhua
Published: August 2022

Background:

Talaromyces marneffei (T. marneffei) is a heat-dimorphic fungus that commonly causes fatal opportunistic infections in immunocompromised patients, such as those with human immunodeficiency virus (HIV) infection. In this case report,

Case Presentation:

In this case report we describe a case of intracranial infection of T. marneffei in a
42-year-old AIDS patient. Contrast enhanced MRI showed the left occipital lobe mass with ring enhancement,
MRS showed elevated AAs and Lip waves in the mass. Surgical resection of the occipital
lobe confirmed the lesion to be T. marneffei infection and possibly with tuberculosis after a pathological
examination. Patients with intracranial ring enhancing space-occupying lesions on MRI should be
considered for intracranial T. marneffei infection. Intracranial T. marneffei infection is relatively rarely
reported and recently studied.

Conclusion:

The MRI in this case suggests that ring enhancement mass and elevated AAs and Lip waves are helpful in the diagnosis of T.marneffei infection.
Serological Evidence and Self-reported Outcomes in Patients with Adrenal Insufficiency during the First Waves of COVID-19 in North-East Italy
Authors: Sabbadin Chiara , Falb Mor Peleg , Voltan Giacomo , Tizianel Irene , Padoan Andrea , Betterle Corrado , Basso Daniela , Plebani Mario , Barbot Mattia , Scaroni Carla , Ceccato Filippo
Published: August 2022

Objective:

COVID-19 is a potentially serious new infection first reported in North East
Italy in Spring, 2020. Patients with adrenal insufficiency (AI) have a known increased risk of infections
that could precipitate to adrenal crisis. Even COVID-19-related psycho-social impact could
affect their health, requiring a dynamic adaptation of daily glucocorticoid (GC) therapy. The aim of
this study was to evaluate the incidence of COVID-19 infection and self-reported outcomes in AI
patients after the first pandemic waves.

Methods:

It was an open-label, cross-sectional monocentric study on 84 (65 primary, 19 secondary)
AI patients resident in Veneto and followed-up in our clinical Endocrine Unit. All patients underwent
serological investigation of anti-SARS-CoV2 IgG, answered the purpose-built “ADDICOVID”
questionnaire in August, 2020, and were re-contacted to reevaluate COVID-19 infection
occurrence in March-April, 2021.

Results:

All patients resulted negative to the serological test for anti-SARS-CoV2 IgG at the end of
the first pandemic wave. After the third wave, COVID-19 infection occurred in 8 patients without
the need for hospitalization. Half patients felt an increased risk of COVID-19 infection, significantly
associated with increased stress and GC stress dose. Only one patient reported stress-correlated
adrenal crisis. The majority of AI workers changed working habits, significantly reducing COVID-
19-related stress.

Conclusion:

AI patients did not show an increased incidence of COVID-19, but the perception of
increased COVID-19 infection risk significantly impacted their psychological well-being, working
habits, and GC daily doses. Therapeutic patient education is crucial, especially for AI workers, to
prevent and treat situations that could lead to an adrenal crisis.
Ondergrondse ruimte als vergeten dimensie
Authors: Van den Driessche Jef , Van Speybroeck Kato , Gruijthuijsen Wesley
Published: August 2022

In ons dagelijkse leven bewegen we ons voortdurend en al dan niet bewust doorheen boven- en ondergrondse ruimtes. Ondanks een lange traditie ontbreekt een geïntegreerde visie op ondergrondse ruimtes echter nog vaak. Voor ruimtelijke planners en architecten is de ondergrond eerder onbekend en zelfs onbemind terrein. Nochtans kan doordacht ondergronds ruimtegebruik een troef zijn om duurzamer met de beschikbare, schaarse ruimte om te gaan.
De ondergrondse weg naar duurzame steden
Authors: Debrock Shana , Van Acker Maarten
Published: August 2022

Onze stedelijke ondergrond is onbekend en onbemind terrein, een letterlijke en figuurlijke black box. Nochtans zit de grond onder onze voeten bomvol potentie om bij te dragen aan de creatie van meer duurzame steden.
Ondergrondse parking zkt. herbestemming
Authors: Ilsbroekx Raf , Van Acker Maarten
Published: August 2022

Steden zetten steeds meer in op een duurzame modal shift met meer ruimte voor fietsers, voetgangers, deelmobiliteit en openbaar vervoer, waardoor ook de parkeerbehoefte in de binnensteden gestaag afneemt. Deze transitie vormde de aanleiding voor onderzoek naar de herbestemmingsmogelijkheden en specifieke opportuniteiten voor ondergrondse stadsparkings.
Spelenderwijs in gesprek over voedselbeleid
Authors: Smaal Sara
Published: August 2022

Gemeenten kunnen op allerlei manieren sociale meerwaarde realiseren binnen het voedselsysteem van hun stad of regio, mits zij hierbij nauw samenwerken met burgers en lokale stakeholders. Op basis van haar doctoraatsonderzoek ontwikkelde Sara Smaal een bordspel waarmee stedelijke actoren met elkaar in gesprek kunnen gaan over de sociale impact van voedselbeleid en voedselinitiatieven. In dit artikel legt ze uit hoe de RE-ADJUSTool werkt en blikt ze terug op het creatieve proces dat ze heeft doorlopen.
The Perception of English Vowels by Kurdish EFL Learners
Authors: Hamid Twana Saadi , Salih Shabang Sardar
Published: August 2022

This paper investigates English vowel perception in a formal classroom setting by Central Kurdish (CK) learners of English (i.e. EFL learners at university level in The Kurdistan Region of Iraq). Ten English vowels were used as stimuli: five monophthongs with similar qualities but different quantities. The participants included 30 first year English majors. They were tested while performing a discrimination task. The task to discriminate 50 pairs of RP English vowel contrasts was an AX style task. The RP vowels differed from the CK vowels in both quality and quantity. As stated by the Perceptual Assimilation Model L2, the results demonstrated a variety of assimilation types (PAM-L2). It was more difficult to distinguish between two sets of similar vowels. Furthermore, closer vowel contrasts in the vowel space were more difficult to distinguish. To the best of our knowledge, no previous research has looked into Kurdish EFL students' perceptions of English vowels. The perception of English vowels by these Kurdish English learners mostly agreed with PAM's predictions, and the results of the discrimination task ranged from excellent to poor.
Mining Severe Drug Hypersensitivity Reaction Cases in Pediatric Electronic Health Records: Methodology Development and Applications
Authors: Yu Yuncui , Zhao Qiuye , Cao Wang , Wang Xiaochuan , Li Yanming , Xie Yuefeng , Wang Xiaoling
Published: August 2022

Background

Severe drug hypersensitivity reactions (DHRs) refer to allergic reactions caused by drugs and usually present with severe skin rashes and internal damage as the main symptoms. Reporting of severe DHRs in hospitals now solely occurs through spontaneous reporting systems (SRSs), which clinicians in charge operate. An automatic identification system scrutinizes clinical notes and reports potential severe DHR cases.

Objective

The goal of the research was to develop an automatic identification system for mining severe DHR cases and discover more DHR cases for further study. The proposed method was applied to 9 years of data in pediatrics electronic health records (EHRs) of Beijing Children’s Hospital.

Methods

The phenotyping task was approached as a document classification problem. A DHR dataset containing tagged documents for training was prepared. Each document contains all the clinical notes generated during 1 inpatient visit in this data set. Document-level tags correspond to DHR types and a negative category. Strategies were evaluated for long document classification on the openly available National NLP Clinical Challenges 2016 smoking task. Four strategies were evaluated in this work: document truncation, hierarchy representation, efficient self-attention, and key sentence selection. In-domain and open-domain pretrained embeddings were evaluated on the DHR dataset. An automatic grid search was performed to tune statistical classifiers for the best performance over the transformed data. Inference efficiency and memory requirements of the best performing models were analyzed. The most efficient model for mining DHR cases from millions of documents in the EHR system was run.

Results

For long document classification, key sentence selection with guideline keywords achieved the best performance and was 9 times faster than hierarchy representation models for inference. The best model discovered 1155 DHR cases in Beijing Children’s Hospital EHR system. After double-checking by clinician experts, 357 cases of severe DHRs were finally identified. For the smoking challenge, our model reached the record of state-of-the-art performance (94.1% vs 94.2%).

Conclusions

The proposed method discovered 357 positive DHR cases from a large archive of EHR records, about 90% of which were missed by SRSs. SRSs reported only 36 cases during the same period. The case analysis also found more suspected drugs associated with severe DHRs in pediatrics.
Internet-Delivered Cognitive Behavioral Therapy for Postsecondary Students: Randomized Factorial Trial for Examining Motivational Interviewing and Booster Lessons
Authors: Peynenburg Vanessa , Hadjistavropoulos Heather , Thiessen David , Titov Nickolai , Dear Blake
Published: August 2022

Background

Internet-delivered cognitive behavioral therapy (ICBT) can improve access to mental health care for students, although high attrition rates are concerning and little is known about long-term outcomes. Motivational interviewing (MI) exercises and booster lessons can improve engagement and outcomes in face-to-face cognitive behavioral therapy.

Objective

This study aimed to examine the use of pretreatment MI exercises and booster lessons in ICBT for postsecondary students.

Methods

In this factorial trial (factor 1: web-based MI before treatment; factor 2: self-guided booster lesson 1 month after treatment), 308 clients were randomized to 1 of 4 treatment conditions, with 277 (89.9%) clients starting treatment. All clients received a 5-week transdiagnostic ICBT course (the UniWellbeing course). Primary outcomes included changes in depression, anxiety, and perceived academic functioning from before treatment to after treatment and at the 1-month and 3-month follow-ups.

Results

Overall, 54% (150/277) of students completed treatment and reported large improvements in symptoms of depression and anxiety and small improvements in academic functioning after treatment, which were maintained at the 1-month and 3-month follow-ups. Pretreatment MI did not contribute to better treatment completion or engagement, although small between-group effects favored MI for reductions in depression (Cohen d=0.23) and anxiety (Cohen d=0.25) after treatment. Only 30.9% (43/139) of students randomized to one of the booster conditions accessed the booster. Overall, no main effects were found for the booster. Subanalyses revealed that clients who accessed the booster had larger decreases in depressive symptoms (Cohen d=0.31) at the 3-month follow-up. No interactions were found between MI and the booster.

Conclusions

Rather than offering MI before treatment, clients may experience more benefits from MI exercises later in ICBT when motivation wanes. The low uptake of the self-guided booster limited our conclusions regarding its effectiveness. Future research should examine offering a booster for a longer duration after treatment, with therapist support and a longer follow-up period.

Trial Registration

ClinicalTrials.gov NCT04264585; https://clinicaltrials.gov/ct2/show/NCT04264585
Impact of an Intelligent Screening App on Drug Clinical Trial Screening Process during the COVID-19 Pandemic: An Experimental Study (Preprint)
Authors: Zhang Qian , Li Bin , Guo Runfang , Zhou Huan , Wang Fuzhi , Liu Peng , Liu Yuanyuan , Zhang Xiaolei , Liu Mulin
Published: August 2022

BACKGROUND

During the COVID-19 pandemic, clinical trial recruitment cannot be carried out due to travel restrictions, transmission risks and other factors, resulting in the stagnation of a large number of ongoing or upcoming clinical trials.

OBJECTIVE

An intelligent screening app was developed using artificial intelligence technology to rapidly pre-screen potential patients for phase I solid tumor drug clinical trials.

METHODS

A total of 429 screening process records were collected from 27 phase I solid tumor drug clinical trials at the First Affiliated Hospital of Bengbu Medical College from April 2018 to May 2021. Features of the experimental data were analyzed, and the collinearity (principal component analysis) and strong correlation (χ2 test) among features were eliminated. XGBoost, random forest, and naive Bayes were used to sort the weight importance of features. Finally, the pre-screening models were constructed using classification machine learning algorithm, and the optimal model was selected.

RESULTS

Among the 429 screening records, 246 (62.12%) were screened successfully. After intersecting the top 15 characteristic variables of different feature screening models, 9 common variables were obtained. To verify the performance of different feature subsets in different machine learning models, 9, 12, and 15 feature subsets based on the above 9 important feature variables were studied to select the optimal feature subset. The results showed that optimal performance, accuracy and practicability were achieved using XGBoost with the 12 feature subset.

CONCLUSIONS

Based on the optimal model, we created an online prediction calculator and visualization app -- ISSP (Intelligent Screening Service Platform), which can rapidly screen patients for phase I solid tumor drug clinical trials. As an auxiliary tool, ISSP optimizes the screening process of clinical trials and provides more convenient services for clinical investigators and patients.
Characterizing Consumer Smartphone Apps for Virtual Reality–Based Exposure Therapy: Content Analysis (Preprint)
Authors: Sunkara Charvi , Thakkar Rajvi , Ong Triton , Bunnell Brian E
Published: August 2022

BACKGROUND

In vivo exposure therapy is the most effective treatment for phobias but is often impractical. Virtual reality exposure therapy (VRET) can help overcome critical barriers to in vivo exposure therapy. However, accessible mobile software related to VRET is not well understood.

OBJECTIVE

The purpose of our study is to describe the landscape of accessible smartphone apps with potential utility for clinical VRET.

METHODS

We conducted a content analysis of publicly available smartphone apps related to virtual reality on the Google Play Store and the Apple App Store as of March 2020.

RESULTS

The initial search yielded 525 apps, with 84 apps (52 on the Google Play Store and 32 on the Apple App Store) included for analysis. The most common phobic stimulus depicted was bodies of water or weather events (25/84, 29.8%), followed by heights (24/84, 28.6%), and animals (23/84, 27.4%). More than half of the apps were visually abstract (39/84, 53.5%). Most apps were free to use (48/84, 57.1%), while the rest were free to try (22/84, 26.2%) or required payment for use (14/84, 16.7%), with the highest cost for use being US $6. The average overall app rating was 2.9 stars out of 5, but the number of ratings ranged from 0 to 49,233. None of the 84 apps advertised compliance with the Health Insurance Portability and Accountability Act, offered the ability to monitor data, provided clinician control over variables in the app experiences, or explicitly stated use by or development with clinicians.

CONCLUSIONS

None of the smartphone apps reviewed were explicitly developed for phobia therapy. However, 16 of the 84 included apps were considered ideal candidates to investigate further as part of treatment due to their accessibility, depiction of phobia-relevant stimuli, low or no cost, and high user scores. Most of these apps were visually abstract and free to use, making them accessible and potentially flexible as part of clinical exposure hierarchies. However, none of the apps were designed for clinical use, nor did they provide tools for clinician workflows. Formal evaluation of these accessible smartphone apps is needed to understand the clinical potential of accessible VRET solutions.
Pembuatan Tepung Jagung Kuning Pramasak dengan Proses Nixtamalisasi serta Karakterisasi Produknya
Authors: Nusantoro Bangun P , Haryadi Haryadi , Bintoro Nursigit , Darmadji Purnama
Published: August 2022

The nixtamalization process of maize is an ancient alkaline-temperature process commonly used in the production of maize-related food products. Whole maize grains are heated in a cooker with an alkaline solution. Then the cooked grains are washed with hot tap water and rested for a while to assure a better distribution of moisture within the maize grains. Unfortunately this nixtamalized maize is not done yet. This research investigates the appropriate cooking time and concentration of alkaline solution. Visual assessment, hardness and lightly to flatten on cooked grains are basis of decision. Afterward, the cooked grains are flattened into chips which could be function as by product. Instant corn flour is obtained by grounding dry chips with a hammer mill. Finally, chemical compositions and physicochemical properties of instant cornflour are evaluated to measure its quality. The nixtamalized maize was done after cooking in 90 minutes at 3%w/w Ca(OH)7 solution and yielded 89% instant corn flour. Resulted corn flour had moisture (10,67%), crude protein (9,15%), crude lipid (5,40%), ash (2,55%) and amylose (26,24%). The resulted data of physicochemical properties showed that instant corn flour had colour (L 84,23; a -0,12; b +24,50), bulk density (606 kg/m3), angle of repose (36,49Â°), swelling power (7,03 g/g), water holding capacity (617%) and digestibility 58,69% in 6 hours.
Efek Antifotoksidatif Ekstrak Andaliman (zanthoxylum Acanthopodium Dc.) terhadap Asam Linoleat
Authors: Suryanto Edi , Raharjo Sri , Sastrohamidjojo Harjono , Tranggono Tranggono
Published: August 2022

Andaliman fruit is a seasoning commonly used in traditional food preparation in North Sumatera. It is also well known as a folk medicine source to cure several kind of illness. The objectives of this study were to determine effect of andaliman extract in photooxidation reaction in model systems. Andaliman was extracted sequentially with hexane, acetone and ethanol. The photooxidation reaction system was consisted of linoleic acid (0,03 M) in methanol containing 100 ppm erythrosine as a sensitizer and the reaction mixture was exposed under 4000 lux fluorescent light for up to 5 hours. Ethanol extract (EHSAE) was found to have the highest anti-photooxidative effect, followed by those of acetone extract (ESHA) and hexane extract (EH), respectively. Linoleic acid treated will ESHAE at 500 ppm concentration and 500 ppm Â±-tocopherol showed lower peroxide value compare to the control samples at 5 hours light exposure in room temperature. However, ESHAE showed any difference in it anti-photooxidative effect than that of Â±-tocopherol as a positive control (p<0.05). The study on the extracting solvent effects indicated than the antiphotooxidative components in the fruit andaliman posses stong polar property and easily extracted with polar solvent. The addition of ethanol extract (ESHAE) showed less blanching ability of erythrosine, followed by acetone extract (ESHA) and hexane extract (HE). These result suggest that the ethanolic extract of andaliman contains components having antiphotooxidative activity.
Uji Kinerja Teknologi Kontrol Tepat Guna untuk Peningkatan Kualitas Produksi Sutera Alam
Authors: Sutiarso Lilik , Suyantohadi Atris , Purwanto Hari , Radi Radi
Published: August 2022

The world demand of raw-silk provides a great opportunity to the development of raw-silk production in Yogyakarta. Recently, only 21% of the overall world demand of raw-silk is fulfilled, whereas Indonesia contributes only 0.1% per year. The main problem is the lack of quality of raw-silk. The optimum growth of silkworm depends on micro environments, i.e. temperature, humidity, aeration, and light intensity. The research aimed at designing an automated “on/off” control technology in the silkworm rearing environmental monitoring in the farming system, while the expected result was high-grade quality of cocoon. In the research, two different conditions of silkworm growing environments were compared, i.e. controlled environment (in the rearing box) and uncontrolled environment. The result indicated that there was increase in  the quality of cocoon. Test of cocoons in laboratory showed that the average thickness of cocoons in controlled rearing environment and in rearing environment was 0.033 cm and 0.029 cm, respectively. The percentage of cocoons in controlled rearing environment was higher than cocoons in normal environment.
Isolasi dan Karakterisasi Lesitin Kelapa dan Wijen
Authors: Hudiyanti Dwi , Raharjo Tri Joko , Narsito Narsito , Noegrohati Sri
Published: August 2022

Lecithin is a natural amphiphilic substance which has unique structures. Lecithin molecules are able to aggregate to form a carrier structure known as liposom which is useful for carrying active substances in drug, food and cosmetics. Lecithin is generally derived from soybeans and eggs. Research efforts have been made to seek new sources of lecithin such as from coconut and sesame seeds. This study aimed to determine the character of plant lecithin derived from coconut and sesame seeds. Isolation of lecithin was done by solvent extraction using a mixture of chloroform-methanol (2:1) and characterization was conducted using TLC, FTIR and GCMS. The results indicated that lecithins from coconut and sesame seeds were from cephalin class with hydrophilic group consisted of ethanolamin. The lipophilic parts of coconut lecithin were C12 and C8 and those of sesame seeds lecithin were C18:1 and C18:0.ABSTRAKLesitin merupakan senyawa ampifil alam yang mempunyai struktur unik. Molekul-molekul lesitin dapat beragregasi membentuk suatu struktur sistem pembawa yang disebut liposom dan berguna pada penghantaran bahan-bahan aktif pada obat, makanan dan kosmetika. Lesitin yang selama ini digunakan pada umumnya berasal dari kedelai dan telur. Upaya penelitian telah dilakukan untuk mencari alternatif sumber lesitin baru yang berasal dari kelapa dan wijen. Penelitian ini bertujuan untuk mengetahui karakter lesitin tumbuhan yang berasal dari kelapa dan wijen. Isolasi lesitin dilakukan dengan cara ekstraksi solven menggunakan campuran kloroform-metanol (2:1). Sedangkan karakterisasi meliputi pengujian dengan TLC, FTIR dan GCMS. Hasil menunjukkan bahwa lesitin kelapa dan wijen adalah lesitin dari golongan sefalin dengan gugus hidrofilnya berupa etanolamin. Bagian lipofil untuk lesitin kelapa adalah C12 dan C8, dan untuk lesitin wijen bagian lipofilnya adalah C18:1 dan C18:0.
Stabilitas Sifat Antioksidatif Lidah Buaya (Aloe vera var. chinensis) selama Pengolahan Minuman Lidah Buaya
Authors: Riyanto Riyanto , Wariyah Chatarina
Published: August 2022

Aloe vera had functional properties as an antioxidant due to its flavonoid compound. However, the use of aloe veraextract were less practical, perishable and low acceptability. Therefore, aloe vera would be processed into aloe vera drink. The purpose of this research was to produce acceptable aloe vera drink with high antioxidative effect. Specifically, the objectives of this research were to evaluate antioxidative activity of aloe vera extract, to evaluate antioxidative properties changes during processing of aloe vera drink based on their ability to scavenge DPPH radicals and to inhibite lipid peroxidation, and to determine process conditions that resulted acceptable product. The research showed that aloe vera extract had high antioxidative activity shown by the percentage of Reactive Scavenging Activity (RSA) of 35.17 % and inhibition of lipid peroxidation of 49.53 %. Blanching of aloe vera gel with the higher temperature, produced aloe vera drink with low antioxidative activity. The antioxidative activity in every stage of processing aloe vera drink decreased especially after immersion in NaCl or lime solution. Processing of aloe vera drink with blanching at temperature of 70 °C produced the most acceptable aloe vera drink with high antioxidative activity.ABSTRAKLidah buaya atau aloe vera memiliki sifat fungsional sebagai antioksidan karena mengandung senyawa flavonoid.Penggunaan lidah buaya dalam bentuk ekstrak kurang praktis, mudah rusak dan akseptabilitasnya rendah. Oleh karena itu dilakukan pengolahan gel lidah buaya menjadi minuman lidah buaya. Tujuan penelitian ini adalah menghasilkan minuman lidah buaya dengan sifat antioksidatif dan akseptabilitas tinggi. Secara khusus tujuannya adalah mengevaluasi aktivitas antioksidasi ekstrak lidah buaya, mengevaluasi perubahan sifat antioksidatif lidah buaya selama pengolahan minuman lidah buaya berdasarkan kemampuannya menangkap radikal bebas DPPH dan menghambat peroksidasi lemak, dan menentukan kondisi proses terbaik yang dapat menghasilkan minuman lidah buaya dengan akseptabilitas tinggi. Hasil penelitian menunjukkan bahwa ekstrak lidah buaya memiliki aktivitas antioksidasi dengan persentase Reactive Scavenging Activity (RSA) sebesar 35,17 % dan penghambatan peroksidasi lemak 49,53 %. Blansing gel lidah buaya dengan suhu semakin tinggi menghasilkan minuman lidah buaya dengan aktivitas antioksidasi rendah. Aktivitas antioksidasi pada setiap tahap pengolahan minuman lidah buaya semakin menurun terutama setelah perendaman dalam larutan NaCl atau larutan kapur. Pengolahan minuman lidah buaya dengan suhu blansing 70 oC dapat menghasilkan minuman lidah buaya yang paling akseptabel dengan aktivitas antioksidasi tinggi.
Pendekatan Multivariat untuk Pengukuran Kualitas Tomat (Lycopersicon esculentum) Berdasarkan Parameter Warna Pendekatan Multivariat untuk Pengukuran Kualitas Tomat (Lycopersicon esculentum) Berdasarkan Parameter Warna
Authors: Masithoh Rudiati Evi , Rahardjo Budi , Sutiarso Lilik , Hardjoko Agus
Published: August 2022

In this study, multivariate linear regression (MLR) was used to predict the content of Brix, total carotene, citric acid,and vitamin C of tomato based on RGB color parameters. Tomatoes were stored at 6 °C and 28 °C then their quality parameters were measured. R, G, and B values were measured non-destructively using computer vision system developed in the previous study. Brix, total carotene, citric acid, and vitamin C were determined by conventional procedures in the laboratory. Data analysis showed that the MLR calibration models could be used to predict Brix, total carotene, citric acid, and vitamin C with R2  of  0.77and 0.72, 0.902 and 0.85, 0.71 and 0.77, as well as 0.88 and 0.82 for temperature of 6 °C and 28 °C, respectively.ABSTRAKPada penelitian ini, multivariate linier regression (MLR) digunakan untuk memprediksi kandungan Brix, karoten total,asam sitrat, dan vitamin C dari tomat berdasarkan parameter warna RGB. Tomat disimpan pada suhu 6 °C dan 28 °C kemudian diukur parameter kualitasnya. Nilai R, G, dan B diukur secara non-destructive dari computer vision system yang dikembangkan pada penelitian sebelumnya. Parameter kualitas Brix, karoten total, asam sitrat, dan vitamin C ditentukan secara destructive dengan prosedur konvensional di laboratorium. Analisis data menunjukkan bahwa model kalibrasi MLR dapat digunakan untuk memprediksi Brix, karoten total, asam sitrat, dan vitamin C dengan R2 sebesar0,77dan 0,72, 0,902 dan 0,85, 0,71 dan 0,77, serta 0,88 dan 0,82 untuk suhu 6 °C dan 28 °C secara berturutan.
Peningkatan Aktivitas Antioksidan Superoksida Dismutase pada Tikus Hiperglikemi dengan Asupan Tempe Koro Benguk (Mucuna pruriens L.)
Authors: Retnaningsih Christiana , Darmono Darmono , Widiarnoko Budi , Muis Siti Fatimah
Published: August 2022

Hyperglycemia is associated with oxidative stress and the pathogenesis of diabetic complications. To reduce the hyperglycemia, modern treatment combined with traditional therapies through functional foods need to be considered, particularly to repair the damaged pancreas beta cells. A foodstuff that has a functionality potential is velvet beans (Mucuna pruriens L), espcially when it is in the form of a fermented product, i.e. tempe. The aim of study was to prove the effect of velvet beans tempe intake on blood glucose levels and superoxide dismutase antioxidant status. This research used randomized controlled group pre test- post test design using 50 male Sprague Dawley (SD) rats aged 2-3 months. The rats were subdivided into 5 groups, 10 rats per group, by means of random allocation. Group 1 is negative control (C-), group 2 is positive control (C+), group 3 is X1-TK10%, group 4 is X2-TK20%, group 5 is X3-TK30%. The groups of C+,X1, X2, X3 are induced by 40 mg/kg body weight stereptozotocin dose by intra peritoneal injection. The research was conducted for 30 days. The data were analyzed with Paired T Test, One-way Anova and continued by the Duncan’s Multiple Range Test. The results showed that streptozotocin injection increased the level of blood glucose and reduced the level of serum superoxide dismutase antioxidant activity. Bioassay experiment demonstrated that velvet bean tempe diet reduced the level of blood glucose. On the other hand velvet bean tempe diet improved the level of superoxide dismutase antioxidant activity.ABSTRAKHiperglikemi menimbulkan stress oksidatif dan patogenesis komplikasi diabetes. Untuk menurunkan hiperglikemi perlu dipertimbangkan kombinasi antara pengobatan modern dengan terapi tardisional melalui pangan fungsional guna mengurangi kerusakan sel beta pankreas. Bahan pangan yang memiliki potensi fungsional tersebut adalah biji koro benguk (Mucuna pruriens L) yang difermentasi menjadi bentuk tempe. Tujuan dari penelitian ini adalah untuk membuktikan pengaruh asupan tempe koro benguk terhadap kadar glukosa darah dan status antioksidan serum pada tikus hiperglikemi. Penelitian ini menggunakan 50 ekor tikus jantan jenis Sprague Dawley umur 2-3 bulan. Tikus dibagi ke dalam 5 kelompok dengan cara random alokasi. Kelompok 1 kontrol negatif (C-), kelompok 2 kontrol positif (C+), kelompok 3 adalah X1-TK10%, kelompok 4 adalah X2-TK10%, kelompok 5 adalah X3-TK10%. Tikus kelompok C+, X1, X2, X3 diinduksi streptozotocin (STZ) dengan dosis 40 mg/kg BB secara inta peritoneal. Penelitian dilakukan selama 30 hari. Data dianalisis dengan Paired T test, One way Anova dan dilanjutkan dengan Uji Wilayah Ganda Duncan. Hasil penelitian menunjukkan bahwa STZ meningkatkan kadar glukosa darah dan menurunkan aktivitas antioksidan SOD serum. Hasil analisis in vivo pada tkus menunjukkan bahwa asupan tempe koro benguk menurunkan kadar glukosa darah dan meningkatkan aktivitas antioksidan SOD serum.
Strategi Pengembangan Agroindustri Berbasis Sistem Usahatani Terpadu di Wilayah Pasang Surut (Studi Kasus: Kabupaten Pulang Pisau Provinsi Kalimantan Tengah)
Authors: Massinai Rustan , Sudira Putu , Mawardi Muhjidin , Darwanto Dwidjono Hadi
Published: August 2022

Central Kalimantan province has tidal swampland with total area of about 5.5 million hectares and it is considered as potential area for agricultural development. Basically, the land can be cultivated for food crop, horticulture, estate and livestock as well as. The purpose of this research was to identify both external and internal factors of integrated farming system at tidal swampland in order to develop agro-industry and to formulate alternative strategy for integrated farming system development at tidal swamp land. The research conducted in Maliku, as sub district of Pulang Pisau, Central Kalimantan Province use field descryptive survey on May to December 2011. SWOT  method was then used to analize data. As a result, there are several strategy options for developing integrated farming: a) expansion of cultivated areas, b) develop agro-industry system, c), improve the quality of human resources, d) provide the access for capital and market expansion, e) increase farm capital. Strategic position issued by local government of Pulang Pisau in order to develop integrated farming is located at level of quadrant I or aggressive development so that strategic development that should be conducted involve “growth-oriented strategy” by using strategy of SO with involving the whole power to achieve opportunity.ABSTRAK Kalimantan Tengah mempunyai luas lahan pasang surut berkisar 5,5 juta hektar merupakan lahan potensial untuk pengembangan pertanian. Pada umumnya sebagian besar lahan tersebut dapat diusahakan untuk tanaman pangan, hortikultura, perkebunan dan peternakan. Penelitian ini bertujuan untuk mengidentifikasi faktor internal dan eksternal dalam pengembangan sistem usahatani terpadu di lahan pasang surut untuk mendukung agroindustri dan untuk memformulasikan alternatif strategi dalam pengembangan sistem usahatani terpadu di lahan pasang surut. Penelitian ini di laksanakan di Kecamatan Maliku dan Kecamatan Pandih Batu Kabupaten Pulang Pisau, dengan metode deskriptif, survei pada bulan Mei 2011 sampai dengan Desember 2011. Metode analisis data menggunakan analisis SWOT. Hasil penelitian diperoleh beberapa pilihan strategi yang dapat dilakukan dalam pengembangan usahatani terpadu di Kabupaten Pulang Pisau Kalimantan Tengah adalah; a) perluasan areal tanaman yang diusahakan, b) membangun sistem agroindustri, c) meningkatkan kualitas sumberdaya manusai (SDM), d) memberikan akses permodalan petani dan perluasan pasar,  e) meningkatkan modal usahatani.  Posisi yang sangat strategis untuk Pemerintah Kabupaten Pulang Pisau dalam mengembangkan usahatani terpadu berada pada kuadran I (pertama) atau tahap pertumbuhan yang agresif sehingga strategi pengembangan yang harus dilakukan adalah growth-oriented strategy atau menggunakan strategi SO, yaitu memanfaatkan seluruh kekuatan yang dimiliki untuk merebut dan memanfaatkan peluang yang sebesar-besarnya.
Pengaruh Varietas Apel dan Campuran Bakteri Asam Asetat terhadap Proses Fermentasi Cider
Authors: Caturryanti Dessi , Luwihana Sri , Tamaroh Siti
Published: August 2022

The objectives of the research were evaluate apple variety and acetic acid bacteria ratio used in cider fermentation. Two apple varieties (Manalagi and Rome Beauty) were used and mixed culture of two bacteria species (Acetobacter pasteurianus INT-7 and Acetobacter aceti JCM 7640) were used for inoculation. Apple extract was inoculated by ratio of acetic bacteria 1:1 and 1:2, and etanol substrat of 5 % was added respectivelly, continued aerobic condition at room temperature for 7 days. The result of the reseach indicated that cider fermentation using Rome Beauty variety with mixed culture of A. pasteurianus INT-7 : A. aceti JCM 7640 = 1:2 produced acetic acid 3.11 %, product yield 0.85 g/g and efficiency 60.56 %.ABSTRAKTujuan penelitian ini adalah untuk mengevaluasi pearan varietas apel dan rasio bakteri asam asetat dalam fermen- tasi cider. Dua varietas apel (Manalagi and Rome Beauty) dan dua kultur bakteri (Acetobacter pasteurianus INT-7 and Acetobacter aceti JCM 7640) digunakan dalam penelitian ini. Ekstrak buah apel dinokulasi dengan bakteri asam asetat dengan rasio 1:1 dan 1:2. Sebagai substrat ditambahkan ke dalam medium fermentasi etanol sebanyak 5 %. Fermentasi silakukan secara aerobik pada suhu ruang selama 7 hari. Hasil penelitian menunjukkan bahwa fermentasi cider menggunakan varietas apel Rome Beauty dengan perbandingan A. pasteurianus : A. aceti = 1:2 menghasilkan asam asetat sebanyak 3,11 %, yield produk 0,85 dan efisiensi sebesar 60,56 %.
Adsorption of Methylene Blue on Nano-Crystal Cellulose of Oil Palm Trunk: Kinetic and Thermodynamic Studies
Authors: Mustikaningrum Mega , Cahyono Rochim Bakti , Yuliansyah Ahmad Tawfiequrrahman
Published: August 2022

The adsorption kinetic study of methylene blue using nano-crystal cellulose made from oil palm trunk was investigated. A sample of 0.08 g of nano-crystal cellulose was used to adsorb 300 mL of methylene blue solution, with a varied stirring speed at 100, 200, and 300 rpm. Meanwhile, the concentration of methylene blue was varied at 1, 2, and 3 mg/L. The experimental results showed that the range of adsorption rate constant was 0.0007–0.0130 m/min. For the thermodynamic study, adsorption temperature was varied at 303, 308, 313, and 318 K. The adsorption capacity values for such temperatures were 10.3389, 10.3802, 10.3614, and 10.3464 mg/g, respectively. It was found that ΔH° value of 0.00742 kJ/mol, ΔS° of 0.7758 kJ/mol K and ΔG° value of −242.81 kJ/mol. Based on the curve-fitting using the Henry, Langmuir, and Freundlich isotherm models, this adsorption tended to the Langmuir isotherm model, where the adsorption formed a monolayer covering the surface of the adsorbent. It was also found that the Langmuir affinity constant (KL) value was 4.560 L/mg, and the maximum adsorption capacity (qm) was 8.590 mg/g.
Surface Complexes of Cr(VI) by Eucalyptus Barks
Authors: Khalil Hind , Maarouf Fatima Ezzahra , Khalil Mariam , Saoiabi Sanaa , Bouhlassa Saidati , Saoiabi Ahmed , Hmamou Mhamed , Azzaoui Khalil
Published: August 2022

The sorption mechanism of hexavalent chromium sorption on eucalyptus barks was evaluated as a function of solution pH for different adsorbent dosages, surface coverage, and the amount of adsorbent. The chromium retention was evaluated based on the distribution coefficient (D), and this retention is attributed to  species, which is predominant between pH 1 and 6.5. The biosorption of Cr(VI) ions onto barks achieved at pH 2.0 in the highest sorbet conditions corresponding to [Cr(VI)] = 10–5 mol (V = 100 mL) is examined for various surface coverage. The surface complexes formed between chromate and eucalyptus barks were found to be > S (HCrO4) and > S (CrO4). Logarithmic stability for log K1–1 and the log K10 values of the complexes were measured and found to be -5.93 in acidic medium and -0.76 in alkaline medium, respectively. Pointed out that the adsorption of Cr(VI) on eucalyptus bark was greater than 90% in all cases, Cr(VI) recovery is strongly acidic dependent and shows maximum retention, for various sorbent amounts, at pH around 2, and this retention is attributed to  species, which is predominant between pH 1 and 6.5, the morphological surface of eucalyptus barks were examined by Scanning Electron Microscope (SEM) connected to a micro analyzer EDS.
Distribution of Heavy Metals in Sediments and Soft Tissues of the Cerithidea obtusa from Sepang River, Malaysia
Authors: Kumar Krishnan , Saion Elias , Yap Chee Kong , Balu Prakash , Cheng Wan Hee , Chong Mee Yoke
Published: August 2022

The main purpose of the research was to analyze the distribution of Arsenic (As), Cadmium (Cd), Copper (Cu), Iron (Fe), Nickel (Ni), Cobalt (Co), Mangan (Mn), and Zinc (Zn) in soft tissues, shells, and associated surface sediments of Cerithidea obtusa (C. obtusa) mangrove snails collected from Sungai Besar Sepang. The concentration of iron (Fe) was found to be the highest in relation to other toxic elements in sediments, soft tissues, and shells of C. obtusa. The concentrations of Cu and Zn in soft tissues of C. obtusa were found to exceed the concentrations in sediments, indicating bioaccumulation of these metals. Metal pollution was assessed with the Enrichment Factor (EF), Geoaccumulation Index (Igeo), and Pollution Factor (CF). EF, Igeo, and CF were 0.34 to 22.41, -3.37 to 2.65, and 0.14 to 9.42, respectively. The results indicate that sediments in Sungai Besar Sepang are contaminated with As and Zn. According to the bivalve bioaccumulation results, the soft tissues of C. obtusa act as a macro-concentrator for Cu and Zn. As a result, it is suggested that ongoing monitoring of releases of heavy metals from anthropogenic sources and stricter environmental protection measures should be implemented.
An Attempt of Determining Some Characteristics of the Moroccan Productive System
Authors: Oulad El Fakir Ahmed
Published: August 2022

The purpose of this paper is to determine some characteristics of the production system of the Moroccan economy for a single product (GDP) with annual data from 1999 to 2019. Then, we try to estimate the TFP from a translog production function to compare it with that corresponding to a Cobb-Douglas production function, if possible. The results obtained show the difficulties encountered in these estimations, particularly the multicollinearity between the explanatory variables.
Evaluation of Moodle OER for Junior Course Business Subjects Students at Botswana Open University’s Centre for Open Schooling
Authors: Hamaluba Tommie , Hamaluba Moono
Published: August 2022

The paper shares some of the challenges and lessons learnt during the COVID-19 pandemic in Botswana and how Botswana Open University stayed resiliently. Our focus is on various aspects of ODeL (students and tutors).The paper discuses MOOODLE portal which was piloted at Botswana Open University’s Centre for Open Schooling in 2021 for Junior Secondary School students of business subjects comprising Commerce, Accounting and Office Procedures. This paper drew inspiration from the fact that MOODLE OERs portal is a niche in Open Schools and the that Commonwealth of Learning (COL), among other objectives offers guidance on use of OER in Open Schools. A total of 50 students were selected randomly from BOU’s five regions and one class of 30 students from a conventional Junior School participated in the pilot which ran for six months from April 2021 September 2021. The portal assisted students to keep learning ongoing, as University needed response to Covid19. There was need and urgency at BOU to address the desperate situation Open Schooling found itself in without tangible eLearning infrastructure. The paper is based on the experiences of the piloting students and tutors, their observations, as well as the literature review and draws recommendations from aforesaid.
Teacher Perspectives of Professional Development and the Implementation of Instructional Practice for English Language Learners
Authors: Scales-Judkowitz Cara Nicole , Panesar-Aguilar Sunddip , Kennedy Brenda
Published: August 2022

An increasing number of U.S. teachers of English Language Learners (ELL) across the nation are not receiving adequate in-service training to provide instruction within students’ Zone of Proximal Development (ZPD). Vygotsky’s ZPD is the difference between what a person can achieve when acting alone and what the same person can achieve when acting with support from someone else. ELL instructional practices should be implemented in ELL students’ ZPD to ensure adequate academic performance. A lack of training is a local problem for a school district in the state of Florida. The purpose of this basic qualitative study was to explore the perspectives of ELL teachers regarding the professional development trainings they received to teach ELL students within their ZPD. The two research questions focused on: (a) how elementary teachers implement instructional practices and resources to teach ELL students within their ZPD and (b) what their perspectives are of the professional development they were provided to teach ELL students. A purposeful sample of eight teachers of ELL students in the first through fifth grades participated in individual interview sessions. Using thematic analysis, data were analyzed using open coding and axial coding. The findings revealed participants’ concerns regarding their knowledge and preparation, as well as the professional development they were offered for teaching the ELL students. An in-service training project was created to provide teachers of ELL students with more information regarding strategies, accommodations, and instructional implementation. This study may contribute to positive social change by highlighting areas of concern for further research. Providing in-service training may equip teachers with the skills and knowledge that they need to teach ELL students within their ZPD, which may result in better educational outcomes.
Karakteristik Sistematika Bahan Ajar Pembelajaran Baca Al-Qur'an Metode Qiraati
Authors: Hilda Hilda Fairuzia Khaidaroh , Faizah Nurul , Faizah Nurul
Published: August 2022

Teaching materials are one of the substantial learning elements in achieving learning objectives. This study aims to determine the characteristics contained in teaching materials for learning to read the Qur'an using the Qiraati method. The method used in this study is a qualitative research method. The data in this study include literature or textual data. Judging from the source of the data, the method of data collection is documentary. This study uses a content analysis method, which is a research method used to draw conclusions that can be corrected according to facts by emphasizing a practical-oriented context from conclusions and explanations about actual symptoms and prediction goals. The results showed that there were different characteristics in each volume. First volume 1: eliminating vague readings by getting used to reading open Harakat Fathah, second volume 2: eliminating reckless or oblique readings (short and unclear) by reading Harakat dhummah, kasroh, fathahtain, kasrohtain, dhummahtain and practicing children carefully read long and short with longer lengths, third volume 3: eliminating prolonged or dragging readings by means of reading breadfruit is pressed not extended nor is tawallud and does not lengthen mad thobi'i and the emphasis should not be broken, fourth volume 4: eliminates readings The Qur'an which is fast but not tartil or Tajwid begins by reading nun sukun with a long hum longer than one alif, fifth volume 5: straightening out the mission of volume IV and qolqolah and eliminating the reading of the Qur'an that is not Tajwid and continuing the mission volume IV, sixth volume 6: eliminating the non-Tajwid reading of the Qur'an and continuing the mission of volumes IV and V.
Saberes e fazeres docente na Educação Infantil e as contribuições do Pibid de Pedagogia da UFAL-Campus do Sertão
Authors: Lima Letícia Campos de , Lima Laíse Soares
Published: August 2022

O Programa Institucional de Bolsa de Iniciação à Docência (Pibid) tem modificado as relações entre teoria e prática, aproximando a universidade da escola pública. Nesse sentido, este texto apresenta a relevância do Pibid para formação inicial de professores, por meio da inserção dos licenciandos no cotidiano escolar. A característica metodológica do Programa de Iniciação à Docência é a pesquisa-ação, no qual os bolsistas apropriam-se do processo formativo, reflexivo, analítico-crítico da ação docente. Assim, este trabalho visa identificar as contribuições do subprojeto de Pedagogia da Universidade Federal de Alagoas-Campus do Sertão para a formação inicial docente na Educação Infantil entre 2014 e 2016. Os relatórios das reuniões periódicas de supervisão e os escritos do diário de campo, provenientes da imersão na turma pré-escolar, foram categorizados e utilizados como materiais de suporte analítico. A análise e a interpretação desses materiais resultaram na compreensão de que as reuniões periódicas de supervisão, planejamento e o instrumento de diário de campo são essenciais para uma prática pedagógica pautada na reflexão-ação-reflexão. Os saberes e os fazeres docente da Educação Infantil, impressos nas atividades desenvolvidas pelos bolsistas, revelam abordagens inovadoras que favorecem a formação integral da criança por meio da educação emancipatória, humanizada e dialógica.