bluuebunny/crossref_metadata_2025 huggingface dataset:
UM VOO SOBRE AS ESCOLAS CRIMINOLÓGICAS E SUAS POSSÍVEIS CONTRIBUIÇÕES PARA A ANÁLISE DE PROGRAMAS DE REMIÇÃO DA PENA PELA LEITURA NO BRASIL
Authors: Antunes Tormin Liana , Pinto Coelho Saulo , Macedo Miranda Bartira
Published: June 2023

O presente estudo faz uma reflexão sobre as possíveis contribuições das escolas criminológicas para a remição da pena pela leitura. Especificamente, busca elucidar subsídios teóricos relevantes para práticas de análise, planejamento e implementação de tais programas de remição. Realiza-se uma sistematização panorâmica (um voo panorâmico) sobre as escolas criminológicas, visando a uma análise organizada de suas características e das respectivas implicações na compreensão das finalidades e norteamentos que devem guiar políticas de remição de pena. Como principais resultados, organizam-se subsídios teóricos no campo da criminologia para apurar a efetividade do Programa Remição da Pena pela Leitura como instrumento de política criminal e assistência educacional no estado de Goiás. Tais subsídios criminológicos devem ser pensados em complementariedade com as referências do constitucionalismo contemporâneo, com o modelo constitucional de processo configurado pela Constituição de 1988 e com a abordagem dos ciclos de políticas públicas.
O “CABO DE GUERRA” DA REGULAMENTAÇÃO DO NOVO FUNDEB
Authors: Arcaro Conci Luiz Guilherme , Talpai Bruno Luis
Published: June 2023

No ano de 2020, o direito à educação foi alvo de uma importante pauta no Congresso Nacional: a aprovação do Novo Fundeb (EC. 108/2020) e a sua regulamentação. Este artigo tem por objetivo discutir, a partir da abordagem de direito e políticas públicas, calcado em uma análise descritiva, o processo de aprovação da emenda constitucional, comparando os processos de transição dos fundos. Far-se-á a análise da movimentação dos atores políticos e interesses envolvidos na construção do texto de regulamentação do Novo Fundeb demonstrando os expedientes governamentais e parlamentares de movimentação política no processo legislativo, utilizados tanto para aprovação de Emendas á Constituição quanto para a sua regulamentação, de modo a compreender o papel dos agentes políticos e as estratégias utilizadas para concretização do direito à educação.
INCENTIVOS FISCAIS COMO INSTRUMENTO DE POLÍTICAS PÚBLICAS À LUZ DO ENFOQUE CRÍTICO DO CONSTITUCIONALISMO CONTEMPORÂNEO
Authors: Lolli Eduardo Henrique , de Oliveira Pinto Coelho Saulo
Published: June 2023

Este artigo se propõe a analisar os incentivos fiscais como instrumento de políticas públicas e os principais desafios para que sirvam efetivamente à concretização dos direitos fundamentais, numa abordagem interdisciplinar, que conjuga o campo de públicas (Ciência Política), o enfoque crítico do constitucionalismo democrático contemporâneo (Direito Constitucional) e a perspectiva da extrafiscalidade (Direito Tributário e Financeiro). O problema subjacente à pesquisa consiste no conflito retórico de narrativas entre governos mais austeros em termos de responsabilidade fiscal no que tange a práticas de incentivos e outros que acentuam o aspecto positivo daqueles instrumentos tributários, sem que haja embasamento empírico suficiente a respaldar uma ou outra conclusão. Para tanto, parte-se de referenciais teóricos como o ciclo de políticas públicas e a importância singular da fase de avaliação baseada em evidência científica; o constitucionalismo do espetáculo enquanto diagnóstico crítico da experiência constitucional contemporânea; a boa administração pública enquanto direito fundamental e, por fim, as ideias de extrafiscalidade e do avesso do tributo para compreender os incentivos fiscais e a decorrente renúncia de receitas como faces da mesma moeda e também instrumentos para concretização de direitos fundamentais, bem como os desafios que esses instrumentos apresentam para a efetividade dos objetivos constitucionais em jogo. A hipótese ventilada neste artigo é a de que, inseridos os incentivos fiscais na dinâmica do ciclo de políticas públicas, a fase de avaliação dos resultados desses instrumentos tributários é aquela que apresenta maiores desafios para sua concretização prática, em detrimento da efetividade daqueles incentivos. O objetivo deste trabalho, portanto, consiste em identificar desafios que se apresentam para contornar essa síndrome de inefetividade (ou de efetividade degenerada), bem como apresentar contribuições teóricas que permitam avançar na direção da efetividade dos incentivos fiscais. Este artigo se vale do método de pesquisa bibliográfica e da revisão da literatura sobre o tema. Por fim, confirma-se a hipótese levantada e conclui-se que, sem avaliação criteriosa acerca da efetividade dos incentivos fiscais como instrumento de políticas públicas, estes tendem a apresentar efeitos negativos à concretização dos direitos fundamentais que, no plano do discurso constitucional, visam a satisfazer.
INCLUSÃO ESCOLAR DE PESSOAS COM DEFICIÊNCIA NO CENÁRIO EDUCACIONAL BRASILEIRO SOB O VIÉS NEOLIBERAL
Authors: De Jesus Pereira Letícia , Rossignoli Marisa
Published: June 2023

O presente trabalho aborda as consequências do novo liberalismo (neoliberalismo) para a educação, mormente para a educação especial de pessoas com deficiência. Assim, tem-se como objetivo geral analisar a inclusão escolar de pessoas com deficiência no Brasil, considerando o discurso neoliberal. Partindo de tais premissas tem-se como problema: quais são as principais consequências do discurso neoliberal para a educação especial sob a perspectiva inclusiva? Os procedimentos metodológicos adotados consistem em estudos bibliográficos, amparados em livros, artigos científicos e demais textos acerca do neoliberalismo e educação especial inclusiva, bem como na pesquisa documental, especialmente dos textos normativos que regulamentam as Políticas Nacionais de Educação Especial no Brasil. Apresenta-se uma pesquisa com abordagem qualitativa, apoiada em uma análise construída a partir de um estudo do conhecimento na área. Conclui-se que as escolas regulares que se dizem inclusivas apenas pela efetivação de matrículas de pessoas com deficiência, na grande maioria das vezes não possuem qualquer apoio que promova o pleno desenvolvimento dessas pessoas, provocando, portanto, a sua marginalização, já que a educação, sob o viés neoliberal, é apenas um produto voltado à satisfação do mercado com a produção de mão de obra.
GARANTIA DE DIREITOS E JUDICIALIZAÇÃO: MEDIDAS SOCIOEDUCATIVAS EM MEIO ABERTO NO RIO DE JANEIRO
Authors: De Oliveira Antonio Carlos , Rizzini Irene
Published: June 2023

Este texto apresenta os principais resultados de uma pesquisa realizada no Rio de Janeiro em 2017 com foco sobre as medidas socioeducativas em meio aberto dirigidas à população adolescente a quem se atribui autoria de ato infracional. Propõe-se a discutir aspectos da execução deste serviço que transitam entre a judicialização e a garantia de direitos dos/as adolescentes atendidos/as. Os autores analisam processos referentes às medidas socioeducativas de Liberdade Assistida (LA) e de Prestação de Serviço à Comunidade (PSC), junto aos Centros de Referência Especializado em Assistência Social (CREAS) do município do Rio de Janeiro, com base na análise de dados que constam nos Planos Individuais de Atendimento (PIAs) e nos prontuários dos/das adolescentes. A pesquisa contribui para a reflexão sobre em que medida as ações inscritas na execução da política pública tendem a responder a um processo estrito de judicialização e/ou a promover a efetivação de direitos humanos e a proteção sócioassistencial dos/das adolescentes e suas famílias.
A EFICÁCIA DO PETI NO COMBATE AO TRABALHO INFANTIL NO BRASIL
Authors: Monteiro de Brito Filho José Claudio , Rocha Ferreira Vanessa , Castro Laís
Published: June 2023

O presente artigo se propõe a discutir a implementação do Programa de Erradicação do Trabalho Infantil (PETI) como política pública eficaz no combate ao trabalho infantil. Trata-se de pesquisa teórica, com a utilização do método dedutivo, eminentemente bibliográfica e documental, por meio de livros pré-selecionados, assim artigos científicos acerca do tema. No primeiro item, discute-se o trabalho infantil e as políticas públicas de inclusão socioeconômicas existentes voltadas para essa finalidade. No item subsequente, analisa-se as particularidades do Programa em si. O terceiro e último item é voltado para o objeto de pesquisa: discutir a eficácia do PETI no combate ao trabalho infantil no Brasil. Por fim, apresentam-se as considerações finais da pesquisa.
PROCESSO ESTRUTURAL E POLÍTICAS PÚBLICAS: O CASO DO PARQUE NACIONAL SERRA DA CAPIVARA
Authors: Carneiro Baldivieso Pablo Enrique , Carneiro Baldivieso Saul
Published: June 2023

O presente artigo tem por objetivo analisar, por meio do estudo de caso, a relação existente entre a concretização de uma política pública e a utilização do processo judicial estrutural. O problema desenvolvido será: Em que medida o processo estrutural pode intervir em políticas públicas ambientais, sem ofender o princípio da separação dos poderes? Partindo deste problema, desenvolve-se a seguinte hipótese: É possível a utilização do processo estrutural na contribuição de instituição de políticas públicas ambientais sem ofensa ao princípio da separação de poderes. Assim, será utilizado o método lógico-dedutivo na pesquisa acadêmica, por meio do estudo de casos, especialmente, o caso do Parque Nacional da Serra da Capivara.
A ADOÇÃO TEORIA DA TRÍPLICE HÉLICE COMO POLÍTICA PÚBLICA
Authors: Giolo Junior Cildo , Saraiva José Sérgio
Published: June 2023

A pandemia causada pela COVID 19, e os seus efeitos econômicos, sociais e políticos, trouxe a discussão da necessidade de inovação, da escolha de prioridades e da busca de cooperação de todas as áreas do conhecimento. Diante desta emergência de saúde e seus reflexos no desenvolvimento das nações, surgiu a necessidade de reinvenção de ideais e de modelos. Neste diapasão, a utilização da teoria do tríplice hélice (academia, iniciativa privada e estado), passa a ser um paradigma a ser seguido como política pública em diversas áreas, como sendo uma nova-velha forma de se buscar grandes soluções para grandes problemas.
O PAPEL DO MINISTÉRIO PÚBLICO NO DESENVOLVIMENTO DE POLÍTICAS SOCIAIS: REVISÃO BIBLIOGRÁFICA DE ARTIGOS ACADÊMICOS (2015 A 2020)
Authors: Suzuki Natália Sayuri , Bernardi Kalil Renan
Published: June 2023

A elaboração e a implementação de políticas públicas, não raro, requerem a participação de atores jurídicos. No Brasil, o Ministério Público tem sido uma das instituições que contribuem para o desenvolvimento de políticas públicas - especialmente, as sociais – desde a promulgação da Constituição de 1988. Diante disso, o objetivo desse artigo é apresentar uma revisão bibliográfica de trabalhos acadêmicos recentes que considera essa atuação do Ministério Público. Para isso, foram elencados artigos disponíveis no Portal da Capes e produzidos entre os anos de 2015 e 2020. Desse modo, foi possível observar que ainda são poucos os trabalhos que se dedicam a essa temática nos periódicos com melhores classificações, o que permite concluir que há possibilidades de expansão e aprofundamento de uma agenda de pesquisa que envolva o Ministério Público e a sua relação com as políticas públicas no país.
Política Nacional de Desenvolvimento de Pessoas
Authors: Alves Caminha Alana , Silva Ferreira Milagres Cleiton
Published: June 2023

A Política Nacional de Desenvolvimento de Pessoas (PNDP) da administração pública federal surgiu como resultado de um esforço do Estado Brasileiro na realização de mudanças voltadas à modernização das instituições públicas federais, por meio do incentivo ao desenvolvimento e aproveitamento das competências do seu quadro de servidores. Entretanto, em se tratando das Instituições Federais de Ensino Superior (IFES), vários são os desafios para a efetiva implementação da política, em virtude da complexidade que abrange os ambientes organizacionais das IFES. Portanto, este estudo objetiva analisar os desafios de implementação da PNDP nas IFES brasileiras com base em pesquisa bibliográfica realizada na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) sobre trabalhos acadêmicos produzidos no âmbito das IFES, no período de 2013 a 2023. Foi utilizada a perspectiva de lentes de análise de Yanow (1990), que busca identificar os fatores intervenientes na implementação de uma política pública por meio de quatro lentes: relações humanas, estrutural, política e sistêmica. Dessa forma, foram analisados os resultados de 11 estudos que evidenciaram desafios diversos para o alcance das finalidades da PNDP nos ambientes dessas instituições, dentre eles, destacaram-se os desafios de ordem estrutural e de relações humanas. Os resultados apontam que a implementação efetiva da PNDP nas IFES brasileiras demanda uma atuação direcionada do órgão central e do próprio quadro de gestores e servidores das instituições, considerando as suas especificidades no sentido de sugerir e adotar metodologias compatíveis com o seu ambiente organizacional.
Illegal Labour Activity: Trends in State Risk Minimization
Authors: Orlova L. N. , Lifanovskaya O. V.
Published: June 2023

Illegal labour activity is a multi-sided notion, which shows a whole set of processes dealing with arising, realizing and terminating labour relations between worker and employer, in case infringement of law and formal standards takes place. The goal of the research is to work out trends of lowering risks of illegal labour activity in national and sectoral aspects. The authors formed the methodological basis of the research by materials of investigations in the field of economic security and shadow economy, illegal and informal labour activity and risk management. Statistic and analytical materials of international and national statistic services were used as information foundation of the research. In the research the authors used general-scientific and specific economic methods that allow us to study the problem of illegal labour activity in a complex way, for instance, content-analysis, statistic analysis, revealing cause and effect links. Serious attention was paid to finding reasons and consequences of illegal labour activity and key branches of economy, where processes of illegal labour activity are the most obvious. Practical importance of the research is connected with using tools of risk management in state regulation and identifying measures of counteraction and barring cases of illegal labour activity. According to the authors state regulation in the field of illegal labour activity shall be based on monitoring and analysis of social and economic situation, forecasting trends and specification of plans of social and economic development.
Econometric Methods of Substantiating Steps Aimed at Passing to the Stage of Extended Population Reproduction in Russisa
Authors: Tikhomirov N. P. , Tikhomirova T. M.
Published: June 2023

The article studies approaches to substantiate lines in social and economic policy of Russia aimed at passing to the stage of extended population reproduction, which became possible after revealing econometric methods of dependence of demographic process intensity indicators on living conditions in the country. As such indicators the authors used maximum and standardized rates of population growth depending only on age birth and death factors and net-coefficient of reproduction. Specific features of their content and methods of their estimation were provided, as well as yearly figures of these indicators in Russia in 2000–2020. Options of econometric models were shown that describe regularity of these indicators changeability depending on factors characterizing living conditions in the country. By using factors of indicator flexibility necessary changes in living conditions were roughly estimated, which could provide transition from depopulation to sustainable growth in population in Russia. The authors critically analyzed the results that are characterized by serious discrepancy in indicators assessing necessary positive changes in living conditions needed to overcome the demographic crisis. It was shown that the most trustworthy estimations correspond to the standardized growth rate.
Approaches to Assessing Knowledge Level of Business-Organization
Authors: Kukushkin S. N , Kalenov O. E.
Published: June 2023

The article assesses the level of knowledge of business - organization with regard to transformation processes taking place in conditions of new economy development. Key stages of business-organization evolution were studied: pre-industrial, industrial and post-industrial, as well as the transition period to economy of knowledge. Specific features of creating and exchanging knowledge at each of the mentioned stages were shown. A model of organization in economy of knowledge was put forward, whose distinguishing feature is priority of organizational culture, knowledge and intangible factors, flexible specialization, relevant management and innovation character of all business-processes, as well as implementation of two key goals: maximum satisfaction of customer needs and development of personal abilities. The authors substantiate specificity of knowledge with regard to its dubious nature and propose methodological approach to assessment of the organization level of knowledge, which is based on analysis of 16 indicators combined in 4 groups: dynamics of business-organization development, system of education and training of personnel, scientific and technical and innovation potential, information system and information support of business-organization. In conclusion algorithm of estimating the index of knowledge level is described and advantages of this method are demonstrated.
Severity of COVID-19 in Pregnant Women: A Review on the Potential
Role of Regulatory T Cells
Authors: Saghafi Nafiseh , Mahmoudi Mahmoud , Momtazi-Borojeni Amir Abbas , Mirzaeian Sara , Tavasolian Fataneh , Sathyapalan Thozhukat , Abdollahi Elham , Sahebkar Amirhossein
Published: June 2023

As a physiological condition, pregnancy may cause temporary alterations in
the hematological, cardiopulmonary, and immune responses, affecting the maternal susceptibility
to viral infections. Pregnant women are vulnerable to infection with the influenza
A virus, hepatitis E virus, MERS CoV, and SARS CoV. The agent of Coronavirus
disease (COVID-19) is the SARS coronavirus (SARS CoV-2), which affects the
cells upon binding to the angiotensin-converting enzyme-2 (ACE2). However, ACE2 expression
is elevated in the placental tissue. However, surprisingly, COVID-19 infection
in pregnant women tends to have a lower severity and mortality. Therefore, it is interesting
to find the immunological mechanisms related to the severity of COVID-19 in pregnancy.
Regulatory T cells (Tregs) are a subset of CD4+T cells that may play a central role
in maintaining maternal tolerance by regulating immune responses. Pregnancy-induced
Tregs are developed to control immune responses against paternal antigens expressed by
the semi-allograft fetus. The role of uncontrolled immune responses in COVID-19 pathogenesis
has already been identified. This review provides insight into whether pregnancy-
induced regulatory T-cell functions could influence the severity of COVID-19 infection
during pregnancy.
High TLX1 Expression Correlates with Poor Prognosis and Immune
Infiltrates in Patients with Lung Adenocarcinoma
Authors: Zhao Liang , Zheng Haiping , Chen Feng , Lu Huasong , Yu Qian , Yan Xuexin , Chen Xinyu , Zhang Qianyu , Bu Qing
Published: June 2023

Background:

To develop optimal personalized therapy for lung
adenocarcinoma (LUAD), potential biomarkers associated with the prognosis are
urgently needed. It is unclear what role T Cell Leukemia Homeobox 1 (TLX1) plays in
LUAD.

Objective:

In this study, TLX1's relationship with LUAD was investigated using TCGA
database analysis, bioinformatics analysis, and experimental validation.

Methods:

We examined the expression of TLX1 in pan cancer and LUAD, the
relationship between TLX1 expression and clinical features, immune infiltration, its
diagnostic and prognostic value, as well as TLX1 related pathways. The analysis
included various statistical methods, including the Kaplan-Meier method, Cox regression
analysis, GSEA, and immune infiltration analysis. TLX1 expression in LUAD cell lines
was validated using qRT-PCR.

Result:

In LUAD patients, high expression of TLX1 was associated with T stage
(P<0.001). High TLX1 expression was associated with worse overall survival (OS) (HR:
1.57; 95% CI: 1.18–2.1; P=0.002). And TLX1 HR: 1.619; 95% CI: 1.012-2.590; P=0.044)
was independently correlated with OS in LUAD patients. TLX1 expression was
associated with the pathways, including Rho GTPase effectors, DNA repair, TCF
dependent signaling in response to WNT, signaling by Nuclear Receptors, signaling by
Notch, chromatin-modifying enzymes, ESR-mediated signaling, cellular senescence,
and transcriptional regulation by Runx1. TLX1 expression was correlated with aDC,
Tcm, and TReg cells. The expression of TLX1 was significantly increased in LUAD cells
compared to BEAS-2B cells.

Conclusion:

An association between high TLX1 expression and poor survival and
immune infiltration was found in LUAD patients. There may be a potential role for TLX1
in diagnosis, prognosis, and immunotherapy for LUAD.
Cerebellopontine Angle Lipoma with Contralateral Sudden Deafness: A Case Report and Review of Literature
Authors: Tang Xuxia , He Xiao , Ge Xinting , Chen Jingjing
Published: June 2023

Background:

Cerebellopontine angle lipoma is a rare tumor that composes less than 1% of all CPA tumors. There has been no recorded case of unilateral CPA/IAC lipoma with sudden contralateral deafness yet.

Case presentation:

We report a 52-year-old man diagnosed with right cerebellopontine angle lipoma and combined left total deafness. Pure-tone audiometry revealed total sensorineural deafness in his left ear and moderate sensorineural deafness in the right ear. The patient was treated with glucocorticoids, batroxobin, and other symptomatic treatments. There was no substantial improvement in hearing after 14 days’ treatment.
Discussion： We chose conservative treatment for him. It is advised to wear hearing aids in the right ear and to undergo regular imaging monitoring.

Conclusion:

Treatment options for such patients should be chosen by taking into account the degree of bilateral hearing loss, the size and location of the tumor, the possibility of preserving hearing during surgery, the functional level of the patient's facial nerve, and other factors.
Mycobacterium Tubercular Mediated Inflammation and Lung Carcinogenesis: Connecting Links
Authors: Vashishth Abhay , Shuaib Mohd , Bansal Tanya , Kumar Shashank
Published: June 2023

Lung cancer is a leading cause of death among all the cancer worldwide and it has the highest occurrence and mortality rates. Mycobacterium tuberculosis (MTB) induced tuberculosis has been known as one of the risk factors for lung carcinogenesis. The exact mechanism of MTB is understood to date. Several research and epidemiological studies about the link between tuberculosis and lung cancer exist. It has been proposed that tuberculosis causes chronic inflammation, which increases the risk of lung cancer by creating a favorable environment. EGFR downstream signaling promotes constitutive activation of TKIs domain due to the mutation in exon 19 and exon 21 (L858R point mutation), which leads to cell proliferation, invasion, metastasis, and angiogenesis, causing lung adenocarcinoma. Several other studies have shown that human monocyte cells infected by MTB enhance the invasion and cause induction of epithelial-mesenchymal transition (EMT) characteristics in lung cancer cell co-culture. This review article has tried to draw a relationship between chronic tuberculosis and lung carcinogenesis.
Optimizing Patient-Reported Outcome Collection and Documentation in Medical Music Therapy: Process-Improvement Study
Authors: Rodgers-Melnick Samuel N , Block Seneca , Rivard Rachael L , Dusek Jeffery A
Published: June 2023

Background

To measure the effectiveness of nonpharmacologic interventions delivered during clinical care, investigators need to ensure robust and routine data collection without disrupting individualized patient care or adding unnecessary documentation burden.

Objective

A process-improvement study was undertaken to improve documentation consistency and increase the capture of patient-reported outcomes (PROs; ie, stress, pain, anxiety, and coping) within a medical music therapy (MT) team.

Methods

We used 2 Plan-Do-Study-Act (PDSA) cycles to improve documentation processes among an MT team (13.3 clinical full-time equivalent staff). Trainings focused on providing skills and resources for optimizing pre- and postsession PRO collection, specific guidelines for entering session data in the electronic health record, and opportunities for the team to provide feedback. Two comparisons of therapists’ PRO collection rates were conducted: (1) between the 6 months before PDSA Cycle 1 (T0) and PDSA Cycle 1 (T1), and (2) between T1 and PDSA Cycle 2 (T2).

Results

Music therapists’ rates of capturing any PRO within MT sessions increased significantly (P<.001) from T0 to T1 and from T1 to T2 for all domains, including stress (4/2758, 0.1% at T0; 1012/2786, 36.3% at T1; and 393/775, 50.7% at T2), pain (820/2758, 29.7% at T0; 1444/2786, 51.8% at T1; and 476/775, 61.4% at T2), anxiety (499/2758, 18.1% at T0; 950/2786, 34.1% at T1; and 400/775, 51.6% at T2), and coping (0/2758, 0% at T0; 571/2786, 20.5% at T1; and 319/775, 41.2% at T2). Music therapists’ feedback and findings from a retrospective analysis were used to create an improved electronic health record documentation template.

Conclusions

Rates of PRO data collection improved within the medical MT team. Although the process improvement in this study was applied to a nonpharmacologic MT intervention, the principles are applicable to numerous inpatient clinical providers. As hospitals continue to implement nonpharmacologic therapies in response to the Joint Commission’s recommendations, routine PRO collection will provide future researchers with the ability to evaluate the impact of these therapies on pain relief and opioid use.
Integrating Generative AI in Healthcare Organisations: Opportunities, Challenges, and Deployment Strategies (Preprint)
Authors: Tan Si Ying , Tan Si Ying , Jin Xin , Hong Wei Zhen , Phua Jason , Keck Camille , Chen Elya , Chew Emily Hwee Hoon , Lau Jacqueline Xiao Xuan , Yip Alexander
Published: June 2023

UNSTRUCTURED

The recent advent of large language models (LLMs), such as ChatGPT, has revolutionised the world of AI and brought the vast potential of generative AI to the fore of many sectors, including healthcare. In this commentary, we discuss opportunities, challenges and strategies of tapping into generative AI, such as the case of enterprise-level LLMs for health system development. Notably, we identified patient outcomes improvement, better patient engagement, healthcare delivery enhancement, healthcare costs reduction and facilitation of research and education in healthcare as some of the opportunities that healthcare organisations could reap from the adoption of generative AI. We also analysed the challenges that healthcare organisations should understand and consider when adopting generative AI, namely, clinical safety, bias and discrimination, transparency and interpretability, data privacy, integration with existing health systems and impacts to the incumbent healthcare workforce. We proposed four different strategies that healthcare organisations could adopt in institutionalizing generative AI. These include adopting a sandbox approach, investing in infrastructure and human capital, building accountability mechanisms in data curation and capacity building for the incumbent healthcare workforce.
Obturator definitif dengan two-piece hollow bulb pada defek pasca hemimaksilektomi
Authors: S Rudy , Wahyuningtyas Endang , Ismiyati Titik
Published: June 2023

Keganasan sering kali terjadi di daerah rongga mulut dan biasanya dirawat melalui tindakan hemimaksilektomi. Tindakan hemimaksilektomi menimbulkan adanya defek yang membuat adanya celah antara rongga mulut dan rongga nasal, sehingga menyebabkan penderita kesulitan saat melakukan fungsi normal seperti menelan dan berbicara. Peran prostodontis dalam menangani adanya defek pada maksila adalah merehabilitasi struktur intra dan ekstra oral untuk memulihkan fungsi normal pengunyahan, fonetik, proses penelanan, dan estetika. Masalah utama rehabilitasi defek yang besar pada maksila adalah berat protesa, sehingga protesa tidak retentif. Tujuan dari laporan kasus ini adalah pembuatan obturator definitif dengan hollow bulb untuk merehabilitasi fungsi pengunyahan, fonetik, proses penelanan, dan estetika. Kasus pasien wanita 24 tahun, tersisa gigi 11, 12, 13, 14, 15, 16, 17, dan 18 disertai dengan defek pada maksila sebelah kiri pasca hemimaksilektomi dengan klasifikasi Aramany klass I. Perawatan yang dipilih adalah pembuatan obturator definitif dengan two-piece hollow bulb dari bahan resin akrilik. Kesimpulan dari laporan kasus iniadalah obturator definitif dengan two-piece hollow bulb dari bahan resin akrilik dapat merehabilitasi defek pada maksila pasca hemimaksilektomi sehingga mengembalikan fungsi pengunyahan, fonetik, proses penelanan, dan estetika.
Overdenture sebagai preservasi tulang alveolar dan retensi gigi tiruan rahang bawah
Authors: Sy Haris Okta Akbar , Kusuma Heriyanti Amalia , Indrastuti Murti , Wahyuningtyas Endang
Published: June 2023

Overdenture merupakan gigi tiruan lepasan sebagian atau lengkap yang didukung oleh satu atau lebih gigi, akar gigi asli, atau implan gigi. Keuntungan penggunaan overdenture adalah menghambat resorpsi tulang alveolar serta memperoleh retensi dan stabilitas yang maksimal. Terhambatnya resorpsi tulang alveolar terjadi karena adanya akar gigi yang dipertahankan. Beberapa jenis penyangga overdenture yang dapat digunakan untuk menambah retensi dan stabilitas adalah bare root, magnet, dan coping. Tujuan dari studi kasus adalah untuk mengkaji penggunaan overdenture sebagai preservasi tulang alveolar dan retensi gigi tiruan rahang bawah. Pasien wanita berusia 52 tahun datang ke klinik Prostodonsia RSGM Prof. Soedomo ingin dibuatkan gigi tiruan dengan keluhan estetik, kesulitan mengunyah dan tidak jelas waktu berbicara. Gigi yang tersisa pada rahang atas hanya gigi 25 dengan kondisi nekrosis, sedangkan pada rahang bawah gigi yang tersisa adalah gigi 31 pulpitis ireversible, gigi 32 karies profunda, gigi 35 nekrosis, gigi 41 dan 42 karies dentin, gigi 43 nekrosis. Tatalaksana kasus adalah kaping pulpa gigi 32, penumpatan gigi 32, 41, dan 42, perawatan saluran akar gigi 25, 31, 35, dan 43, pembentukan bare root pada gigi 25, pegangan magnet pada gigi 35 dan 43, pemasangan short coping pada gigi 31. Insersi menunjukan retensi dan stabilitas gigi tiruan baik. Pada saat kontrol, pasien merasa puas karena gigi tiruan tersebut dapat memperbaiki estetis, fungsi pengunyahan dan bicara. Kesimpulan dari penggunaan overdenture magnet dan coping dapat mencegah terjadinya resopsi tulang alveolar serta meningkatkan retensi gigi tiruan rahang bawah.
Pengaruh aplikasi wound dressing kepompong ulat sutera (Bombyx mori) terhadap kepadatan kolagen dan kekuatan tarik luka insisi kulit
Authors: Indrapradana Adyaputra , Hasan Cahya Yustisia , Dwirahardjo Bambang
Published: June 2023

Kepompong ulat sutera (Bombyx mori) merupakan material yang sangat biokompatibel dan memiliki kemampuan regenerasi yang baik terhadap jaringan tubuh manusia dan studi terkini juga menunjukkan bahwa material ini digunakan sebagai wound dressing. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan wound dressing dari kepompong ulat sutera terhadap kepadatan kolagen dan kekuatan tarik luka pada penyembuhan luka insisi kulit. Tikus Wistar jantan sesuai kriteria inklusi sebanyak 28 ekor dibagi secara acak ke dalam 4 kelompok,masing-masing kelompok 7 ekor, berdasarkan waktu dekapitasi dan berdasarkan bahan dressing (dressing kasa sebagai kelompok kontrol dan kepompong ulat sutera sebagai perlakuan). Masing-masing tikus mendapatkan insisi sepanjang 3 cm di kulit punggung tikus dan dijahit 3 simpul simple interrupted dengan benang nylon 4.0. Luka insisi pada punggung tikus ditutup dengan bahan dressing sesuai dengan kelompoknya. Pengamatan kepadatan kolagen dan kekuatan tarik luka dilakukan pada hari pengamatan ke-7 dan ke-14. Uji statistik independent t-test menunjukkan kepadatan kolagen kelompok wound dressing kepompong ulat sutera (bombyx mori) lebih padat dari kelompok kontrol, baik pada pengamatan hari ke-7 (p = 0,000) dan ke-14 (p = 0,000). Kekuatan tarik kelompok wound dressing kepompong ulat sutera (bombyx mori) lebih tinggi dari kelompok kontrol, baik pada pengamatan hari ke-7 (p = 0,000) dan ke-14 (p = 0,000). Penggunaan wound dressing kepompong ulat sutra meningkatkankepadatan kolagen dan kekuatan tarik penyembuhan luka insisi kulit tikus Wistar secara signifikan. Semakin padat kolagen akan meningkatkan kekuatan tarik.
Tatalaksana lesi oral untuk mendukung asupan nutrisi pasien toxic epidermal necrolysis
Authors: Christine Helen , Dewi Tenny Setiani , Permatasari Dewi Kania Intan
Published: June 2023

Toxic Epidermal Necrolysis (TEN) merupakan reaksi kulit yang berat akibat hipersensitifitas berupa gangguan mukokutaneus akut ditandai epidermolisis lebih dari 30% luas permukaan tubuh disertai gangguan sistemik dan dapat mengancam jiwa. Asupan nutrisi yang adekuat sangat penting untuk pemulihan dari kerusakan jaringan, terutama asupan protein. Keterlibatan mukosa rongga mulut pada TEN berupa lesi erosi pada membran mukosa yang menimbulkan kesulitan makan. Seorang wanita berusia 31 tahun dirujuk dari bagian Ilmu Kesehatan Kulitdan Kelamin dengan keluhan lecet dan gelembung berisi cairan jernih pada hampir seluruh tubuh disertai nyeri menelan sehingga pasien sulit makan sejak 2 hari yang lalu. Pasien didiagnosis TEN ec suspect fenitoin, diazepam dan asam mefenamat. Anemia defisiensi Fe, infeksi saluran kencing, drug induced liver injury, hipoalbuminemia dan hiponatremia. ditemukan dari hasil pemeriksaan laboratorium. Pemeriksaan ekstra oral menunjukan seluruh wajah, leher dan dada terdapat makula kecoklatan disertai daerah erosi pada bagian leher, mata anemis, sklera non ikterik, bibir atas dan bawah bengkak disertai krusta sanguinolenta. Pemeriksaan intra oral ditemukan lesi erosif eritema multipel pada hampir seluruh mukosa rongga mulut. Diagnosis kerja yaitu lesi oral terkait Toksik EpidermalNekrolisis. Terapi yang diberikan berupa kompres bibir larutan dexametason bergantian dengan NaCl 0,9% serta pemberian chlorhexidine gluconate 0,2% mouthwash. Seminggu kemudian pasien mengalami perbaikan dan dapatmakan makanan biasa. Kesimpulan dari penanganan dini yang adekuat terhadap manifestasi oral pasien TEN akan mendukung kondisi sistemik dengan meningkatnya asupan nutrisi sebagai bagian dari perawatan komprehensif.
Gambaran cone-beam computed tomography pada kasus Cleidocranial Displasia
Authors: Nursari Efie Mariyam , Priaminiarti Menik , Kiswanjaya Bramma , Fauziah Eva , Bachtiar-Iskandar Hanna H
Published: June 2023

Cleidocranial dysplasia (CCD) merupakan kelainan herediter yang mempengaruhi tulang dan gigi serta diwariskan secara autosomal. Meskipun radiograf dua dimensi dapat memberikan informasi diagnosis CCD, namun memiliki keterbatasan distorsi geometrik dan superimposisi. Laporan kasus ini memaparkan dua kasus CCD yang berbeda dan mengevaluasi gambaran radiograf dengan menggunakan modalitas pencitraan Cone-Beam Computed Tomography (CBCT) dengan tujuan untuk memberikan gambaran radiografis lengkap melalui CBCT sebagai salah satu alatpenunjang diagnosis yang memberikan rekonstruksi akurat, sehingga diharapkan dapat membantu dalam menegakkan diagnosis dan menentukan rencana perawatan. Dua orang pasien berusia dua belas dan sembilan tahun dikonsultasikan dari bagian Ilmu Kedokteran Gigi Anak untuk melakukan pemeriksaan pencitraan 3D CBCT. Temuan radiografik gigi multiple supernumerary di rahang atas dan bawah serta keterlambatan pertumbuhan gigi-gigi permanen pada kedua pasien, serta adanya kelainan tumbuh kembah pada struktur kranium, tulang-tulang wajah, maksila dan mandibula. CBCT mengatasi kelemahan atau kekurangan pada radiograf dua dimensi, khususnya evaluasi dalam arah bukolingual. Pencitraan 3D CBCT memungkinkan rekonstruksi yang akurat dan dari beberapa pandangan sagital, koronal dan aksial dari gigi supernumerari sehingga dapat dengan tepat menentukan jumlah, posisi, morfologi mahkota dan juga hubungannya dengan gigi permanen yang berdekatan sehingga memudahkan dalam menentukan rencana perawatan.
Pengaruh ekstrak biji pepaya (Carica papaya Linn) terhadap tingkat inflamasi gingivitis (studi in vivo pada Rattus norvegicus)
Authors: Suryono Suryono , Pahlevi Muhammad Reza , Afifah Nisaul , Prayitno Prayitno
Published: June 2023

Gingivitis adalah peradangan gingiva yang disebabkan oleh akumulasi plak subgingiva. Plak akan meningkatkan aktivitas sel fagosit dan mediator inflamasi. Infiltrasi sel inflamasi terutama neutrofil polimorfonuklear akan menyebabkan inflamasi yang dapat diamati secara klinis. Indeks gingiva menunjukkan derajat inflamasi pada gingivitis. Penurunan indeks gingiva dapat disimpulkan sebagai penyembuhan peradangan. Pengobatan gingivitis adalah scaling, root planning, dan terapi obat anti inflamasi non steroid (NSAID). Terapi menggunakan NSAID merupakan upaya untuk memodulasi respon host pada inflamasi. Biji pepaya dapat digunakan untuk memodulasi respon inang karena mengandung flavonoid, saponin, dan polifenol yang memiliki efek antiinflamasi, antibakteri dan antioksidan. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak biji pepaya terhadap derajat inflamasi pada gingivitis tikus wistar. Tiga puluh ekor tikus wistar dibagi menjadi 5 kelompok yaitu kontrol negatif, kontrol positif, dan tiga kelompok ekstrak biji pepaya dengan konsentrasi 0,2%, 2% dan 20%. Gingivitis diinduksi dengan menempatkan ligatur sutera retentif plak pada gigi seri mandibula dan Aggregatibacter actinomycetemcomitans inokulasi sulkus gingiva. Ekstrak diterapkan dua kali sehari. Tikus didekapitasi pada hari kedua dan kelima kemudian dibuat preparat histologi fragmen gingiva. Perbedaan yang signifikan diamati pada indeks gingiva antara kelompok perlakuan dan kontrol negatif. Penelitian ini juga menemukan penurunan indeks gingiva setelah perawatan dengan ekstrak biji pepaya. Kemudian disimpulkan bahwa ekstrak biji pepaya dapat menghambat inflamasi dan menurunkan derajat inflamasi pada gingivitis tikus wistar.
SECONDARY HOST PLANTS OF WATER LILY APHID, RHOPALOSIPHUM NYMPHAEAE (HEMIPTERA: APHIDIDAE) IN SERBIA
Authors: Milenković Darija , Žikić Vladimir , Stanković Saša S. , Lazarević Maja , Petrović-Obradović Olivera , Ilić Milošević Marijana
Published: June 2023

The water lily aphid is a cosmopolitan species that feeds on various plants. Its primary hosts are Prunus species from which they migrate to their secondary hosts – aquatic and semi-aquatic plants. So far, in Serbia, Rhopalosiphum nymphaeae is recorded to attack only three plant species as secondary hosts. In our study, conducted in September 2020, we have researched the association of water lily aphid with secondary hosts in wetland habitats. A total of 44 samples were collected from 16 localities. In addition to the plant species previously reported, in this study 11 secondary hosts are documented for the first time in Serbia. The most common trophic association of R. nymphaeae was with Salvinia natans which was registered in 13 localities. There is a high possibility of finding new records of secondary hosts, therefore, more research is needed to complete the information about the water lily aphid and its hosts in Serbia.
Conspiraciones en la democracia
Authors: Fernández Vega José
Published: June 2023

La difusión de distintos tipos de teorías paranoicas parece tener una influencia creciente en la opinión pública de las democracias contemporáneas. Se intenta revisar aquí algunas fuentes clásicas que podrían explicar los orígenes y alcances de estas formas de pensar la política. A partir de la revisión de diversas aportaciones, como las de historiadores o teóricos como Freud, Popper y Canetti, se intentará desentrañar algunas características del pensamiento conspirativo sobre la sociedad. Para actualizar el tema se recurre también a reflexiones de pensadores como Eco y Bobbio, entre otros. Según se argumenta, la crisis de legitimidad de nuestros sistemas políticos proporciona un trasfondo para la proliferación de explicaciones paranoicas, alimentadas también por la despolitización y el predominio de las demandas subjetivas en la arena pública.
Las interacciones en segunda persona: pragmática afectiva y normatividad
Authors: Pérez Miguel Ángel
Published: June 2023

En lo que sigue esbozo tres posibles vías de desarrollo de la propuesta de Pérez y Gomila sobre la perspectiva de la segunda persona de la atribución mental que, en su conjunto, dejan ver la importancia de caracterizar finamente las relaciones entre lo mental y lo normativo en la perspectiva de la segunda persona. Las tres vías que propongo parten, aunque van más allá, de algunos hallazgos de la teoría de la pragmática afectiva. Me centraré en los casos de interacción en segunda persona más que en las atribuciones en segunda persona y adoptaré como caso paradigmático la relación que se establece entre un bebé y su cuidadora.
Emociones, interacción humana y poder: comentarios a Social Cognition and the Second Person in Human Interaction, de Diana Pérez y Antoni Gomila
Authors: Rojas-Velásquez Diana
Published: June 2023

En este comentario destaco algunas virtudes de la propuesta de Diana Pérez y Antoni Gomila en Social Cognition and the Second Person in Human Interaction y planteo dos preguntas. La primera es acerca del papel de las emociones básicas en las interacciones uno a uno a nivel grupal e intergrupal. La segunda se refiere a la influencia que tienen las posiciones de poder en las relaciones humanas y la forma en que éstas alteran o modifican la lectura de los estados mentales.
Percepciones de estudiantes de magisterio sobre la escritura académica
Authors: Adoumieh Coconas Nour , Nin Rachel , Báez Yamely
Published: June 2023

El objetivo de este artículo es analizar las percepciones sobre escritura académica y su posible puesta en práctica, luego de un conjunto de actividades de enseñanza explícita. La metodología se centró en una investigación de campo y de alcance descriptivo. Se aplicó un cuestionario solicitando diez afirmaciones sobre el proceso de escritura académica como estrategia autorreflexiva a fin de crear un perfil identitario de los sujetos después de un proceso formativo. Los informantes de este estudio fueron un grupo de veintidós estudiantes de magisterio del Instituto Superior de Formación Docente Salomé Ureña (ISFODOSU), de República Dominicana. Las afirmaciones fueron tratadas con la técnica del análisis de contenido para lo cual se crearon categorías inductivas. Los datos se procesaron con MAXQDA 2022. Los resultados revelaron que los estudiantes que transitan por talleres de alfabetización académica muestran mayor interés por la escritura y la investigación, son conscientes de la complejidad de estos procesos y de los esfuerzos implicados en el logro de los objetivos.
Detection of Unhealthy Citrus Leaves using Deep Neural Network
Authors: Saaquib Mohammad Aftab
Published: June 2023

Abstract: This research paper presents a novel approach for detecting unhealthy citrus leaves using deep neural networks (DNNs). By leveraging convolutional neural networks (CNNs) and a comprehensive dataset of healthy and diseased citrus leaf images, we train a robust model for accurate classification. Data augmentation and transfer learning techniques are employed to enhance the model's performance. Extensive evaluation demonstrates the superiority of our approach. Our automated method contributes to plant health monitoring, facilitating timely interventions and optimizing crop yield for sustainable agriculture
Analysis of Drinking Water Quality in Honakere Hobli
Authors: K P Preetham , T G Pavan Gowda , A Sahana , J K Shridhara , Mahadevaiah Dr. T.
Published: June 2023

Abstract: Water is the most essential and valuable natural gift to mankind as well as the producer and consumer of this planet. Without water there would have been no life, hence it is a matrix of life.It is vital for many aspects of economic and social development. To analyse water quality, different approaches like statistical analyses of individual parameters, multi-stressors water quality indices. Rivers are the lifeline of living beings and constitute an integral part of both rural and urban communities as a source of drinking and cooking purposes. Water used by the public must be free from disease-causing bacteria, toxic chemicals, and excessive amounts of minerals and organic matter. It is important to test the suitability of water quality for its intended purpose, whether it is livestock watering, irrigation, spraying, or drinking water. The purpose of this section is to provide water quality testing information for the village of Nagamangala Taluk that will assist residents using a water supply. It provides information on the importance of water quality monitoring. Out of 20 villages, 8 villages’ water samples are not ideal for drinking purposes because of the higher concentration of TDS, TH, Cl, Ca, SO4, Fe, alkalinity, Mg, and Cd is more in that water samples. And other village water samples are suitable for drinking purposes. Since most of the families from the economically weaker sections of the society directlyconsume the tap water supplied by the village water supply system without any treatment.However, it is important to monitor the quality of drinking water regularly in rural areas where there is more population growth.
Curiosity dalam kehidupan sehari-hari
Authors: Bayuningrum Wardah Arum
Published: June 2023

One important thing to achieve the best academic results, one important thing is needed, namely curiosity. Curiosity isrequiredtoobtainnewinformationandisconsideredthedrivingforceinvolvedinmakingnewconnectionsbetween ideas, perceptions, concepts, and representations. This article aims to review research on the role of curiosity in everyday life. We review conducted on 20 research results published in international journals between 2000 and 2017. The review results show that curiosity has an essential and consistent role in inﬂuencing a person’s life positively or negatively. Someone who has a high curiosity aspect, then that person will explore information, willingness and desire to search for information, have adventures with information, and be more active in asking other people.
Hubungan komitmen afektif dengan iklim organisasi dimediasi oleh organizational citizenship behaviour pada karyawan
Authors: Ilmawati Vitavela
Published: June 2023

Organizational environment can affect organizational productivity. The interaction of employees with the organizational environment is referred to as organizational climate. Organizational climate is influenced by affective commitment and organizational citizenship behaviors. The purpose of this study was to determine the relationship between affective commitment and organizational climate mediated by organizational citizenship behaviors. Research subjects 174 staff. Data retrieval using random sampling technique and the method of Mediating Multiple Regression analysis. Collecting data using the Clior Scale to measure the organizational climate variable, the OCQ Scale to measure the affective commitment variable and the OCB Scale to measure the organizational citizenship behavior variable. The results show that organizational citizenship behaviors can mediate the relationship between affective commitment and organizational climate. This study shows that affectively committed employees can reduce negative aspects in the company so that they will show OCB behavior by complying with all company regulations and maintaining good relations with all members of the organization then it can create a positive organizational climate for the company.