bluuebunny/crossref_metadata_2025 huggingface dataset:
The interaction of transmission intensity, mortality, and the economy: a retrospective analysis of the COVID-19 pandemic
Authors: Morgenstern Christian , Laydon Daniel , Whittaker Charles , Mishra Swapnil , Haw David , Bhatt Samir , Ferguson Neil
Published: November 2022

The COVID-19 pandemic has caused over 6.4 million registered deaths to date, and has had a profound impact on economic activity. Here, we study the interaction of transmission, mortality, and the economy during the SARS-CoV-2 pandemic from January 2020 to December 2022 across 25 European countries. We adopt a Bayesian vector autoregressive model with both fixed and random effects. We find that increases in disease transmission intensity decreases Gross domestic product (GDP) and increases daily excess deaths, with a longer lasting impact on excess deaths in comparison to GDP, which recovers more rapidly. Broadly, our results reinforce the intuitive phenomenon that significant economic activity arises from diverse person-to-person interactions. We report on the effectiveness of non-pharmaceutical interventions (NPIs) on transmission intensity, excess deaths and changes in GDP, and resulting implications for policy makers. Our results highlight a complex cost-benefit trade off from individual NPIs. For example, banning international travel increases GDP however reduces excess deaths. We consider country random effects and their associations with excess changes in GDP and excess deaths. For example, more developed countries in Europe typically had more cautious approaches to the COVID-19 pandemic, prioritising healthcare and excess deaths over economic performance. Long term economic impairments are not fully captured by our model, as well as long term disease effects (Long Covid). Our results highlight that the impact of disease on a country is complex and multifaceted, and simple heuristic conclusions to extract the best outcome from the economy and disease burden are challenging.
Investigation and Analysis of Absorption in One-Dimensional Dielectric-Metal Photonic Crystal Absorbers
Authors: Alanazi Tarek I.
Published: November 2022

This paper investigates the spectral response of a one-dimensional dielectric-metal photonic crystal absorber. The reflection and absorption spectra are obtained by applying the transfer matrix method (TMM) in the frequency range of 0.1 THz to 10 THz. The effects of influencing factors like the incident angle, thickness and material of the metal and dielectric layers on the absorption spectrum of the absorber are explored. Finally, a high-efficient absorber with a comprehensive free spectral range (FSR) of 1.46 THz and fitness of 2.496 is proposed. The numerical calculations show that high absorption of 99.37% and a high reflection of 3.23% are achievable for the absorber. Therefore, the absorber can be used as a perfect absorber and a perfect reflector over a wide range of frequencies.
Preparation and evaluation of a functional effervescent powder based on inclusion complexes of orange oil and β-cyclodextrin derivatives
Authors: Fadel Hoda , Lotfy Shereen , El-Aleem Fatma Abd , Ahmed Mohamad Sayed , Asfour Marwa , Taleb Sally Abou , Saad Rasha
Published: November 2022

Flavoured functional effervescent powders are becoming increasingly popular by consumers due to their health benefits and easy dissolution. In present study, orange flavoured effervescent powders having functional properties were prepared. Orange oil (O) was blended with different essential oils (EOs) having high antioxidant activity. The orange oil and the O-EOs blends were subjected to gas chromatography-mass spectrometry (GC-MS) analysis and evaluation of radical scavenging activity. Combinations of two water soluble β-cyclodextrine polymers, 2-hydroxypropyl-β-cyclodextrine (2-HP-β-CD) and epihydrin-β-cyclodextrin (EPI-β-CD) were prepared at different molar ratios (3: 1 and 1: 3, F1 and F2, respectively). The O-EOs blends that showed the highest antioxidant activities and best odour qualities were encapsulated with F1 and F2, separately. The orange flavoured inclusion complexes were prepared by freeze drying method. The particle sizes of the inclusion complex powders were in the nanoscale. Characterization of the inclusion complexes nanoparticles were performed by scanning electron microscopy (SEM), Fourier transform infrared microscopy (FT-IR). The results confirmed the successful formation of the inclusion complexes. However, inclusion complex of O-EOs blend with F1 (O-F1C-IC) showed the smallest particle size (113.9 ± 15.9 nm), the more negative zeta potential (-27.1 ± 1.27 mV), the highest encapsulation efficiency (95.51%) and best odour quality. Therefore, it was mixed with an effervescent powder having high acceptable characteristics. The orange flavoured effervescent powder showed superior flowability.
Fabrication and Evaluation of Biodegradable Alginate Bead Controlled Release Fertilizer for the Controlled Release on Nitrogen
Authors: Hwang Dong Ki , Cho Ha Young , Thanh Truong Vu , Kim Hyeri , Kim Hyo Jeong , Jeon Hyeonyeol , Oh Dongyeop X. , Park Jeyoung , Koo Jun Mo
Published: November 2022

Controlled-release fertilizers (CRFs) are a next-generation type of fertilizers, with several advantages over conventional fertilizer. However, using non-degradable and petroleum-based materials in the fabrication of CRFs possess considerable threat to agricultural soils and the environment. Therefore, this study aimed to develop a highly biodegradable, nontoxic, and biocompatible CRFs based on calcium alginate (CaAlg) beads. The results showed that the sphericity of the beads increased with decreasing CaCl2concentration and increasing gelation time. Additionally, there was a significant decrease in the viscosity of sodium alginate (NaAlg) suspension with increasing concentration of urea. Moreover, there was an increase in the urea loading (UL) efficiency and a decrease in the urea release rate of the beads with increasing concentration of CaCl2. Furthermore, carrots grown in the control soil and soil containing urea were larger compared with those grown in soils containing CRF, indicating the controlled release of nitrogen by the CRF. Adding humic acid (HA), poly vinyl acid (PVA), and citric acid to the suspension increased the stability and improved the urea release profile of the CRF. Overall, the fabrication process is easy and could be applied for the mass production of CRFs.
Anemia in patients with hidradenitis suppurativa
Authors: Revankar Rishab , Rojas Mary , Walsh Samantha , Patel Heli , Revankar Nikita , Han Joseph , Parameswaran Anupama
Published: November 2022

IMPORTANCE
Hidradenitis suppurativa (HS) is associated with a number of physical and psychological comorbidities. Studies have suggested an association between HS and anemia; however, this association is not widely understood and may result in delayed diagnosis and treatment and possible increase in morbidity and mortality.
OBJECTIVE
To systematically review and perform a metanalysis regarding the association between HS and anemia, and to characterize the subtypes of anemia associated with HS.
DATA SOURCES
A search of the EMBASE, Medline, Web of Science Core Collection, and Cochrane Central Register of Controlled Trials databases from the time of database inception to September 25, 2022, yielded 313 unique articles.
STUDY SELECTION
All observational studies and randomized controlled trials published in English that examined the odds ratio (OR) of anemia in patients with HS were screened by 2 independent reviewers. Case reports were excluded. Among 313 unique articles, 7 were deemed eligible.
DATA EXTRACTION AND SYNTHESIS
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines facilitated data extraction. The Newcastle-Ottawa Scale (NOS) was used to analyze risk of bias of included studies. In addition to OR and 95% confidence intervals, relevant data on patient demographics and anemia subtypes were also extracted.
MAIN OUTCOMES AND MEASURES
The primary outcome was the OR of anemia in HS patients. This study also attempted to characterize anemia subtypes associated with HS.
RESULTS
In total, 2 case-control and 5 cross-sectional studies featured a total of 11,693 patients. Among the studies, 4 of 7 demonstrated a statistically significant positive association between anemia and HS (ORs, 2.20 [1.42 to 3.41], 2.33 [1.99 to 2.73], 1.87 [1.02 to 3.44], and 1.50 [1.43 to 1.57]), with macrocytic and microcytic subtypes being most common. After adjusting for publication bias, meta-analysis with random effects revealed HS to be associated with increased odds of anemia compared to non-HS groups (OR 1.59 [1.19, 2.11])
CONCLUSIONS AND RELEVANCE
There is a statistically significant positive association between HS and anemia, particularly for the aforementioned subtypes. Patients with HS should be screened for anemia. In case of lower hemoglobin concentration, the anemia of HS patients should be subdivided according to mean corpuscular volume of the red blood cells and further investigated depending on subtype.
Implementation of a telerehabilitation program for oncosurgical patients during the COVID-19 pandemic: perspectives and user satisfaction
Authors: Parraguez Luz Alejandra Lorca , Ribeiro Ivana Leao , Hinojosa Marta Pizarro , Troncoso Jorge Plasser
Published: November 2022

Introduction

Many rehabilitation services in the face of the COVID-19 health emergency have had to adapt face-to-face interventions with remote care through telerehabilitation. We aim to describe the implementation of a telerehabilitation program during the COVID-19 pandemic for patients who are candidates for elective cancer surgery in a low-income Chilean public hospital. Secondarily, describe the perspectives and satisfaction of users with the program.

Material and methods

Correspond to a descriptive and retrospective study. Implementation was measured in terms of, recruitment rate, retention, dropouts, and occurrence of adverse events. User perspectives and satisfaction were evaluated through a survey composed of nine items on a Likert scale with five response options. Descriptive analyses were considered with mean, standard deviation, minimum, maximum, as well as absolute and relative frequency. For patients' perspectives on the program, a qualitative analysis was considered to describe them. The most relevant domains were identified in a text box to illustrate the results.

Results

155 patients were referred to the telerehabilitation program, with 99.3% recruitment, a retention rate of 46.7% and no adverse events reported. In relation to user satisfaction, in general, patients showed good satisfaction with the telerehabilitation program except items 1 and 8 of the survey. Thirty-three patients reported their perspectives on the intervention, represented in 12 domains.

Conclusion

It is possible to implement a telerehabilitation program for oncosurgical patients in the context of preoperative care during the COVID-19 pandemic, with good user satisfaction. Likewise, this study provides guidance for other health institutions that wish to implement a telerehabilitation program.
Forecasting seasonality and trend of tuberculosis prevalence in India using SARIMA-NNAR Hybrid model
Authors: Baikunth Baikunth Kumar Yadav , Su Sunil Kumar Srivastava , Pranveer Pranveer Singh
Published: November 2022

Early detection of tuberculosis (TB) is very important for control and prevention. We aim to study the current status of tuberculosis prevalence in India by applying an appropriate model that can forecast TB incidence by analyzing the seasonality and trends using past time series data. Notified TB incidence data was extracted from open resources, i.e., Central Tuberculosis Division (CTB), Government of India from 2017 to 2019. A SARIMA model and a hybrid model combining SARIMA with Neural Network Autoregressive (SARIMA-NNAR) models were applied to fit the data and forecast the notified TB incidence. Counterfeiting performance parameters, MSE, RMSE, MAE, MPE, MASE, and MAPE were used to analyze the goodness fit of the models. Reported notified TB incidence data of 2020 were used to validate the models. Both models could reasonably predict and forecast the notified TB incidence, but a hybrid model demonstrated better results when compared to the individual models. In the hybrid model, the RMSE, MAE, and MAPE were (5260.359), (3910.648), and (2.080665) respectively whereas in the SARIMA model the corresponding values were (6712.889), (4863.659), and (2.644319) respectively. Therefore, the hybrid model was more effective in predicting the seasonality and trend of TB incidence than the individual SARIMA model. The hybrid model showed better TB incidence forecasting than the SARIMA. This model will help the government to develop better control strategies for the overall management, control, and eradication of the disease.
Going viral: a science communication collaboration in the era of COVID-19 and social media
Authors: Wiles Siouxsie , Morris Toby , Priestley Rebecca
Published: November 2022

On 9 March 2020, two days before the World Health Organization declared COVID-19 a global pandemic, microbiologist and infectious diseases expert Associate Professor Siouxsie Wiles released the first output from her collaboration with cartoonist Toby Morris: an animated GIF (Graphics Interchange Format) known as ‘Flatten the Curve’. The graphic went viral on Twitter with over 10 million impressions in three days. Flatten the Curve was the first of more than 70 graphics produced by the Wiles and Morris collaboration, all designed as accessible visual communication about COVID-19. The graphics, all released under a Creative Commons CC-BY-SA-4.0 license, have been translated into multiple languages, used by communities, politicians, and public health officials around the world, and the collaborators have won multiple awards for their work.
Gear manufacture process by using chilled ductile iron casting
Authors: Guterres Natalino Fonseca D. S.
Published: November 2022

Ductile Iron has been used many times for the manufacture of components by casting, one of them is gears. The gear manufacturing method is one of the determinations of gear performance in service life. Wear and contact fatigue are important cases to consider during gear operation and the cause is surface hardness and dimensional accuracy. The purpose of this study was to investigate the surface behavior and gear profile dimension accurately. Gear chilled casting using an open mold made of silica sand. The chill will be coated to the surface of the mold wall then pouring at a temperature of 1400oC. Chill creates a good cooling rate on the surface to form FeC3 and M7C3 and (FeCrC)7C3, then produce a hardness of 700-994.96HV. Using chill thickness is 0.4mm, the dimensional accuracy of tooth thickness, pitch circular, and addendum circle diameter is very precise after the finishing process.
On the evidence for a statistical-computational gap raised by the Group Testing Problem
Authors:   , Gebhard Oliver
Published: November 2022

Although everyone is familiar with using algorithms on a daily basis, formulating, understanding and analysing them rigorously has been (and will remain) a challenging task for decades. Therefore, one way of making steps towards their understanding is the formulation of models that are portraying reality, but also remain easy to analyse. In this thesis we take a step towards this way by analyzing one particular problem, the so-called group testing problem. R. Dorfman introduced the problem in 1943. We assume a large population and in this population we find a infected group of individuals. Instead of testing everybody individually, we can test group (for instance by mixing blood samples). In this thesis we look for the minimum number of tests needed such that we can say something meaningful about the infection status. Furthermore we assume various versions of this problem to analyze at what point and why this problem is hard, easy or impossible to solve.
A PROSPECTIVE STUDY ON ACUTE LIMB ISCHEMIA - PRESENTATION, MANAGEMENT, OUTCOME- OUR INSTITUTIONAL EXPERIENCE
Authors:   Assistant Professor, Institute Of Vascular Surgery, MMC,Chennai., Mch Ramya , Mch Jayachander ,   Professor, Madras Medical College, Chennai., Venkateshwar R. ,   MCH Vascular Surgery Post Graduate, Madras Medical College, Chennai., Ephreme Noble Collins ,   MCH Vascular Surgery Post Graduate, Madras Medical College, Chennai.
Published: November 2022

Introduction:Acute limb ischemia (ALI) a major vascular emergency defined as sudden decrease in limb perfusion that threatens limb viability. Prompt early recognition and management is need of hour to reduce the morbidity and mortality associated with ALI. The aim of this study is to emphasis on presentation, management and outcome of ALI for better understanding of disease and management Materials And Method: 1. Period Of Study - 10months from OCT 2021 - JULY 2022 2. Total No Of Patients â€“ 100 3. Study method â€“ prospective observational study Results: The study enrolled 100 patients with sudden onset of six Ps (pain, pallor, poikilothermia, pulselessness, paresthesia, paralysis) and treated within 14 days of onset. Mean age group was 47.32 (18-80yrs) and 72% were male and 28% female, among which 66% were lower limb and 34% upper limb ALI. 26%class I, 18% class IIa, 32%class IIb, 24% class III. All patients were primarily treated with anticoagulation and 26 recovered. 36 patients had systemic lytic therapy with inj. Alteplase. 13 CDT were performed. 23 patients underwent thrombo/embolectomy with a balloon catheter (Fogarty). 15 patients underwent surgical bypass following lytic therapy and had successful revascularization of limb. 39 patients finally ended up with amputation in spite of intervention. 4 patients died and all 4 had saddle embolus with B/L LL ALI. Conclusion: In patients presenting with ALI, Major limb salvage ability factors â€“ type and class of ischemia, etiogical factor, time of presentation to vascular specialist.Time is essence in salvaging the limb in ALI â€“ act FAST.Class III ALI interventions have limb salvage ability rate of 17%, reduced the level of amputation and promotes stump healing- decreasing the morbidity.
BACTERIAL AND FUNGAL PATHOLOGIES OF TOMATO (SOLANUM LYCOPERSICUM L.): STATUS OF THE DISEASES AND CONTROL PRACTICES OF FARMERS IN TOGO
Authors:   Ecole Superieure dAgronomie, Universite de Lome, Togo., Banito Agnassim , Bamazi Bitang ,   Ecole Superieure dAgronomie, Universite de Lome, Togo., Tedihou Ekanao ,   Institut Togolais de Recherche Agronomique, Lome, Togo., Kamde Kpatcha ,   Institut Superieur des Metiers de lAgriculture, Universite de Kara, Togo., Tchalla Pouwereou ,   Institut Superieur des Metiers de lAgriculture, Universite de Kara, Togo., Sikirou Rachidatou ,   Institut National des Recherches Agricoles du Benin, Cotonou, Benin.
Published: November 2022

Tomato (Solanum lycopersicum L.) is of great socio-economic Tomato (Solanum lycopersicum L.) is of great socio-economic importance. Unfortunately, its production is limited in Togo by fungal diseases and bacterial wilt caused by Ralstonia solanacearum (Rs). The objectives of the study are to establish the status of major tomato diseases in Togo and control approaches used by the producers. The methodology led to a field survey allowing the evaluation of the incidence of fungal and bacterial diseases of tomato and the identification of their endogenous control methods. In the laboratory, the isolation and identification of the pathogens responsible for these diseases were carried out. The results show that the major diseases of tomato in Togo were, spots, organ decay and wilting plants. The incidence rate of fungal diseases ranges from 18.8% to 75% (fields) and from 0% to 15% (plants). The pathogens responsible are Sclerotium rolfsii (7.5%) Sclerotinia sclerotiorum (1.5%), Alternaria solani (2.5%) and Fusarium oxysporum (4.38%). The incidence rate of Rs wilt is 100% (field) and ranges from 10% to 43.33% (plant). The PCR test revealed that the bacterium responsible for tomato wilt in Togo is Rs belonging to phylotype I, Sequevar 17. Synthetic chemical pesticides are used to control these pathologies, which is a problem for human and animal health and environmental protection. Chemical pesticides have been identified, 60% of which are insecticides and 30% fungicides. The study revealed unproper practices in the management of pesticides in region covered by the research, leading to sanitary risks for farmers.
A STUDY TO ASSESS THE EFFECTIVENESS OF CRYOTHERAPY AS PAIN MANAGEMENT AFTER THE ADMINISTRATION OF CHEMOTHERAPEUTIC AGENTSAMONG CANCER PATIENTS IN SELECTED HOSPITALSOF GANDHINAGAR
Authors:   Associate Professor Apollo Institute of Nursing, Gandhinagar., Chingshubam Jibanlata
Published: November 2022

A Quasi-experimental study was conducted to assess the effectiveness of cryotherapy as pain management after the administration of chemotherapeutic agents amongcancer patients in selected areas of Gandhinagar. The study was conducted among cancer patients receiving chemotherapy in selected areas of Gandhinagar.
SARCOMES PHYLLODES GEANTS : A PROPOS DE DEUX CAS
Authors:   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat., Zineb Aboueddahab , Chaymaa Mohammadine ,   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat., Chaimae Aboueddahab ,   Service Cardiologie Hopital Avicenne Rabat., Hassani Moulay El. Mehdi El. ,   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat Universite Mohamed V, Faculte De Medecine Et De Pharmacie de Rabat., Abdellah Babahabib ,   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat Universite Mohamed V, Faculte De Medecine Et De Pharmacie de Rabat., Guelzim Khalid ,   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat Universite Mohamed V, Faculte De Medecine Et De Pharmacie de Rabat., Jaouad Kouach ,   Service Gynecologie Obstetrique Hopital Militaire Dinstruction Mohamed V Rabat Universite Mohamed V, Faculte De Medecine Et De Pharmacie de Rabat.
Published: November 2022

Les sarcomes phyllodes sont des tumeurs malignes rares du sein, ils font aussi partie du groupe des tumeurs phyllodes. Ils presentent des signes cliniques et mammographiques identiques a ceux des lesions benignes. Letude anatomopathologique associee a limmunohistochimie permet de confirmer le diagnostic. Le traitement de reference est une mastectomie simple ou une tumorectomie large sans curage ganglionnaire. Lassociation dun traitement adjuvant par radiotherapie ou chimiotherapie est encore discutee. Nous rapportons deux cas de sarcomes phyllodes geants.
An Exploration of the Quality Assurance Roles of the Various Regulators of Human Resources for Health Training in Zambia
Authors: Katwizi Kango Mabvuto
Published: November 2022

This inquiry was conducted following reports that questioned the quality of higher education in Zambia, including the quality of Human Resources for Health (HRH) training. One of the notable reports was from research conducted by the Zambia Medical Association (2019). This inquiry built on all these reports by focusing on the roles of the various regulators (also referred to here as Actors) on how their individual and collective roles can play a role in improving the quality of HRH training in Zambia. Ideally, one does not expect to see any challenges in the quality of HRH training because when reading the acts and mandates of the various actors (summarized in Table 1), such as HPCZ, HEA, ZAQA, and local government authorities, there appears to enough authority to provide quality assurance. The inquiry focused on what could have gone wrong and what could have been improved. Keywords: Actors, Human Resources for Health (HRH), Intersectoral collaboration, Quality, Regulators, Training.
Effects of Gadolinium-Based Contrast Agents on the Kidney, Liver, and Heart of Wistar Rats
Authors: Olumide Egbeyemi Oluwafemi
Published: November 2022

The harmless potential of gadolinium-based contrast agent (GBCA) used in MRI studies was remarkable until when gadolinium was detected in the brain, bones, and skin. This study aimed to evaluate the effect of four GBCAs on the liver, heart, and kidney of Wistar rats. Twenty-five (25) male Wistar rats weighing 165-239 g were divided into 4 experimental and control groups after obtaining ethical approval from the Institutional Review Board (IRB) of the Nigerian Institute of Medical Research (NIMR). Specimens in the experimental groups received 2.5 mls / day of one GBCA and the control same normal saline through the lateral tail for 5 days consecutively / week. The Livers, Hearts and Kidneys were harvested 4 weeks following last injection. Pathohistology showed all kidney tissues exposed to Gadopentetate, 80 % to Gadodiamide, and 40 % to Dotarem and Cyclolux were inflamed. Sixty percent Gadodiamide and Doterem to the liver tissue, 50 % and 20 % to Gadopentetate and Cyclolux also inflamed. Samples exposed to Gadopentetate and Dotarem had 50 and 40 % of their heart tissue inflamed. Only those to Gadodiamide and Cyclolux were not affected. Injuries like necrosis, degeneration, and hypertrophy were also noted in all the tissues. All GBCAs were statistically significant in all tissue studied. Gadolinium-based contrast agents had a weak negative correlation with inflamed and degenerated tissues, also a weak positive correlation with hypertrophied tissue, but a moderate positive correlation with necrosis tissues of the kidney, liver, and heart. Keywords: Contrast agents, Heart, Histopathology, Kidney, Liver, Magnetic resonance imaging.
Covid-19 Vaccine Hesitancy in Northern Nigeria
Authors: D.S. Adeniyi,
Published: November 2022

The rapid development of the Covid-19 vaccine candidates through new and improved technologies and the rapidity with which these vaccine candidates were trialed and approved for public administration was highly commendable. However, the rapid administration of the Covid-19 vaccines raises a lot of concern among various world populations. This concern, relating directly to the safety and intents of the big pharmaceutical companies and governments, has led to the greatest form of health promotion initiative resistance in recorded human history. The universal level of hesitancy against the Covid-19 vaccines is now a subject of major concern among public health experts. This study which seeks to identify factors fostering Covid-19 vaccine hesitancy was conducted among the COVID-19 vaccine hesitant populations in Northern Nigeria. Findings from this study indicate that 84% of the study population makes use of the internet and other social media platforms for their news information sources. 42% of the study population would follow the guidance of their healthcare workers on issues relating to the Covid-19 vaccines. Covid-19 vaccine hesitancy in Northern Nigeria is largely fostered by a lack of appropriate information and a huge knowledge gap about the Covid-19 vaccines. It is, therefore, imperative that Government engages the young people of Northern Nigeria as critical stakeholders in the fight against Covid-19 vaccine hesitancy. Proper and tailored health educational programs, and meaningful engagements of religious leaders, parents, and healthcare workers in health promotion activities can help overcome the current challenge of Covid-19 vaccine hesitancy in Northern Nigeria. Keywords: Covid-19, Healthcare Workers, Immunization, Vaccine, Northern Nigeria, Vaccine Hesitancy.
Making the Law Work for Human Resources for Health (HRH) Training in Zambia
Authors: Katwizi Kango Mabvuto
Published: November 2022

There are several institutions in Zambia that play an important role in regulating the quality of higher education, including Human Resources for Health (HRH) training. However, there were reports of overlaps in the legal mandates of these institutions. In 2021, one of the institutions, the Higher Education Authority (HEA), responded to this challenge by successfully facilitating the amendment of the laws that regulated the quality of higher education. This research investigated whether the amended laws were still suitable enough to ensure quality in higher education and in HRH training. Keywords: Actors, HRH, Law, Regulators, Training, Quality.
Access to Finance: Determinants and Limitations to the Demand Side of Finance for Liberia’s Rural Market
Authors: Saye Gbatu Andy
Published: November 2022

This study reviews the theoretical literature regarding determinants and the limitations to the demand side of rural finance in Liberia with the coming into effect of the National Financial Inclusion Strategy (NFIS). The outcome of this study reveals that education, income level, household assets, and agriculture rank as the outstanding drivers of the demand for finance in Liberia’s rural market. Obviously, the demand for financial services in the rural market of Liberia is very high. However, the demand is limited by a litany of factors such as slow economic growth & lack of job opportunities, poor public infrastructure, structural unemployment, few diversification opportunities, seasonality in agriculture, imperfect information & supervision, and poor social protection and market failures. The keywords used by the author in this article encompass creditworthiness, information asymmetry, financial inclusion, Pareto efficiency, poverty alleviation, and rural finance. Keywords: Credit worthiness, Financial inclusion, Information asymmetry, Pareto efficiency, Poverty alleviation, Rural finance.
Relações de gênero nos processos decisórios sobre a água em Ouro Preto/MG
Authors: Rosa Alexsandra Matilde Resende , Guarda Vera Lúcia de Miranda , Alves Kerley dos Santos
Published: November 2022

A integração da perspectiva de gênero na gestão dos recursos hídricos visa a garantir que as experiências e preocupações de homens e mulheres façam parte da preparação, efetivação, controle e avaliação das políticas e programas sobre a água. Tal integração é necessária na medida em que as mulheres são minorias nas altas instâncias decisórias sobre os recursos hídricos, mas são muito afetadas pela escassez deles. Ademais, as mulheres lidam com a água diariamente ao longo de gerações. Também, representam metade da população mundial, e o desenvolvimento sustentável não pode acontecer sem a contribuição de parcela tão significativa da população. Essa pesquisa teve como objetivo identificar a percepção dos gestores da água no município de Ouro Preto/MG quanto à participação das mulheres na gestão. Buscou-se atingir esse objetivo por meio da aplicação de questionários, entrevista semiestruturada e observações nas reuniões dos Órgãos e Conselhos participantes da pesquisa. Foi observada uma maior presença masculina nos cargos gerencias e operacionais dos Órgãos e nos Conselhos Gestores. Apesar de estarem em menor número, as mulheres assumem um posicionamento ativo. Os entrevistados relatam observar uma maior presença de homens nas reuniões, sendo necessárias medidas que incentivem a participação das mulheres. Ainda, foram relatadas diferenças de funções conforme o sexo no ambiente de trabalho. De acordo com a percepção dos conselheiros e trabalhadores, a participação popular, em geral, nos Órgãos e Conselhos, é pouco expressiva. Há a necessidade de cursos de capacitação para garantir uma maior equidade de forças dentro do debate ambiental sobre o assunto, permitindo debates mais equânimes.
Direito humano ao meio ambiente sadio, fake news e princípio jurídico da fraternidade: um caminho possível para a ODS 13
Authors: Porto Carolina Silva , Machado Jaborandy Clara Cardoso , Machado Carlos Augusto Alcantara
Published: November 2022

Levando em consideração os avanços tecnológicos que permitem a disseminação rápida e sem controle de notícias e informações dos mais diversos tipos, o presente artigo busca analisar de que maneira o fenômeno das fake news impacta na concretização do Objetivo de Desenvolvimento Sustentável 13 – ação contra a mudança global do clima. Além disso, investiga de que forma o princípio jurídico da fraternidade, dentro do contexto jurídico-social brasileiro, pode ser um instrumento apto a orientar e efetivar o direito humano ao meio ambiente sadio e, em consequência disso, o ODS 13. A partir disso, desenvolveu-se uma pesquisa baseada no método quantitativo, utilizando abordagem dedutiva e descritivo-argumentativa, elaborada a partir de pesquisa bibliográfica, para concluir que, atualmente, os fatores pecuniários e ideológicos atuam como grande motivadores para a disseminação de notícias falsas e que, por este motivo, o disparo de fake news é um grande óbice à concretização do ODS 13. Dessa maneira, são necessários investimentos – tanto do Estado quanto da sociedade civil – em educação e conscientização da população, para fomentar o senso de coletividade e solidariedade recíproca, típicos de uma sociedade fraterna.
The Doctrine of Fiduciary Obligations in Corporate Law Through the Prism of Fiduciary Legal Relations and the Principles of Justice, Conscience, Reasonableness and Loyalty
Authors: Urazova Hanna
Published: November 2022

Topicality. The relevance of the study is due to the lack of a single approach to understanding fiduciary legal relations in civil studies, which prevents the disclosure of the essence of the doctrine of fiduciary duties; insufficient analysis of the concept of "fiduciary duties", which makes it impossible to determine the content of duties arising from the subject of fiduciary legal relations; the lack of clarification of the essence of the doctrine of fiduciary duties, which prevents its full application to the regulation of civil legal relations, the prosecution of persons who have fiduciary duties.
The purpose of the article is to reveal the essence of the doctrine of fiduciary duties through the prism of fiduciary legal relations and the principles of civil law, in particular, justice, good faith, reasonableness and loyalty, using the example of corporate law.
Research methods. A complex of methods was used in the study of the problem. The theoretical and methodological basis is dialectical, historical and comparative methods, with the help of which the processes of formation, development and application of the doctrine of fiduciary duties in Ukraine and foreign countries were investigated and a complex conceptual and categorical apparatus of this doctrine was developed. Methods of analysis, synthesis, logical generalization, scientific abstraction, and formal-logical methods were used. Using the classification method, groups of fiduciary duties were identified. The method of theoretical generalization made it possible to establish subjects that have fiduciary duties.
Results. An analysis of fiduciary legal relations, their relationship with the doctrine of fiduciary duties, the mechanism of functioning of the latter in the Romano-Germanic and Anglo-American legal systems was carried out; special legal methods of interpretation of legal norms, with the help of which the conceptual principles of the functioning and development of the doctrine of fiduciary legal relations, as well as the directions of its practical implementation in judicial practice, are defined; the norms of the current legislation relating to fiduciary duty in corporate law, the application of the doctrine of fiduciary duty in the practice of the Supreme Court were investigated; the components of the doctrine of fiduciary duties are defined: fiduciary legal relations, fiduciary powers, fiduciary duties, principles of justice, good faith, reasonableness and loyalty; the essence of the doctrine of fiduciary duties in corporate law is revealed.
SEMICARBAZONAS: SEQUÊNCIA DIDÁTICA INTERDISCIPLINAR EM AULAS EXPERIMENTAIS DE QUÍMICA ORGÂNICA E QUÍMICA MEDICINAL
Authors: Oliveira Vanessa , Sá Ingredy , da Silva Georgtown , Santos Victória , Araújo Cleônia , Gonsalves Arlan
Published: November 2022

SEMICARBAZONES: INTERDISCIPLINARY APPROACH IN EXPERIMENTAL CLASSES OF ORGANIC CHEMISTRY AND MEDICINAL CHEMISTRY. Considering the chemical and pharmacological properties of semicarbazones, an interdisciplinary didactic sequence was developed to be applied in experimental classes of undergraduate courses in Pharmacy, Chemistry and related areas. This didactic sequence was planned in three steps, starting from the planning of the target molecule, a semicarbazone derived from helional, to its synthesis, physicochemical characterization (CCD, melting point, FTIR and UV-Vis) and in silico tests of its pharmacokinetic properties using the free software ADMETlab 2.0. The proposed target molecule has as molecular scaffold the 1,3-benzodiaxole nucleus and the semicarbazone function, aiming to obtain a molecule with promising anticonvulsant action and that can be obtained by a low cost and easy to execute methodology, which makes it attractive for use in experimental classes. Thus, the application of this didactic sequence aims to provide undergraduate students the opportunity to experience the process of drug development, applying techniques for planning, synthesis, characterization, and pharmacokinetic evaluation in silico. Besides reinforcing the interdisciplinary teaching of Medicinal Chemistry, applying in an integrated way the theoretical and practical knowledge of the disciplines of Organic Chemistry, Physical Chemistry, Pharmacology and Computational Chemistry.
Baru Seed Extracted Oil (Dipteryx alata Vog.): Chemical Composition and Thermal and Oxidative Stability
Authors: Paulo Linamarys , Fernandes Raquel , Gandra Kelly , Minim Valéria , Minim Luis , Grimaldi Renato , Vidigal Márcia
Published: November 2022

Baru seeds are commonly found in the Brazilian savanna and present potential to be used by the food industry due to their high content of fat. In this sense, this study aimed to determine the physicochemical properties, and chemical composition of baru seed oil. The thermal and oxidative stability, as well as the interfacial properties of the oil were also evaluated. The free fatty acid, peroxide, moisture, density, viscosity and the refractive index of the oil extracted from baru seeds were 0.08% oleic acid, 6.69 meq O2 kg–1 of oil, 0.03%, 0.92 g cm–3, 32.9 mPa s and 1.47, respectively. Since linoleic acid (L), oleic acid (O), palmitic acid (P) and linolenic acid (Ln) are the main fatty acids present in the oil, the most common predominant triacylglycerols in the oil are POO, POL, OOO, OOL, OLL and LLL. The oil extracted from baru seeds presented good thermal and oxidative stability. Moreover, the oil contains high contents of total phenolics and carotenoids. The reduction of oil-water dynamic interfacial tension was promoted by the presence of small molecules. Therefore, the oil extracted from baru seeds presents promising properties for processing in the food industry.
Motivation and Interest in Traveling of Young Traveler During Revenge Tourism
Authors:   Department of Hospitality Management, Universitas Pelita Harapan Jl. M. H. Thamrin Boulevard 1100 Lippo Village Tangerang 15811 - Indonesia, Then Julita , Yulius Kevin Gustian ,   Department of Hospitality Management, Universitas Pelita Harapan Jl. M. H. Thamrin Boulevard 1100 Lippo Village Tangerang 15811 - Indonesia
Published: November 2022

Revenge tourism is a travel trip that is meant to take revenge after the end of the pandemic period and is carried out for those who have previously canceled their tour due to the pandemic. Young travelers are one of the fastest growing and most dynamic markets of the tourism sector in this study, their motivation and interest in traveling are influenced by several factors. The study uses a descriptive quantitative approach with the aim of looking at the motivations of young travelers in traveling after the pandemic ends. With the purposive sampling method, it was found that the motivations that influence young travelers' interest in traveling during revenge tourism are escape motivation, relaxation, strengthening family bonds, self-fulfillment, romance, wish fulfillment, financial security, and leisure time. While the motivation that has no effect is the motivation to play, prestige, social interaction, and educational opportunity.
Studi Kelayakan Bisnis Pembangunan Hotel ABCD dari Aspek Pasar dan Pemasaran
Authors:   Sekolah Tinggi Pariwisata Bogor, Jl. Curug Mekar No. 17, Yasmin. Kota Bogor, Jawa Barat 16113, Indonesia, Hambali Hasan , Prihanto Agus ,   Program Studi D3 Perhotelan, Sekolah Tinggi Pariwisata Bogor Jln. Curug Mekar No. 17,Yasmin. Kota Bogor, Jawa Barat 16113, Indonesia
Published: November 2022

The city of Bekasi is a city of industry, trade, and services making the city of Bekasi suitable to be used as a good investment place. The level of tourist visits that always increases every year makes the level of hotel visits always increases every year. Hotel development requires a large amount of financing, making business studies necessary. This research methodology uses a qualitative descriptive method. The results of the analysis show that the market and marketing aspects include market segmentation, guests from Indonesia and abroad, etc. SWOT includes Strengths of the hotel to be built has many advantages, Weaknesses in the form of traffic jams and Bekasi is not a tourist city, Opportunities high opportunities by looking high demand for rooms, and Threats of having several competitors who already have names. The conclusion from the above analysis can be said that the ABCD hotel from the market and marketing aspects is feasible to build.
Impact of Vitamin D Supplementation on Menstrual Cycle Irregularities
among Women with Polycystic Ovary Syndrome who were Treated with
Metformin: A Systematic Review with Meta-Analysis
Authors: Alenzi Ebtihag O.
Published: November 2022

Background:

There is inconsistency in the evidence about the effect of adding vitamin D
supplements to metformin therapy among women with polycystic ovary syndrome (PCOS).

Objective:

In this systematic review, we described the differences in menstrual cycle irregularities between
women who received vitamin D supplementation and those who didn’t receive vitamin D
among women who diagnosed with PCOS and received metformin.

Methods:

We reviewed previous literature to identify all relevant studies. The included studies' quality
and risk of bias were assessed using the Consolidated Standards of Reporting Trials (CONSORT) and
the Reporting of Observational Studies in Epidemiology (STROBE) instrument. Cochrane's Q-test and
I2 statistic were used to assess the heterogeneity across included studies. The fixed-effect model was
used to calculate the total effect size.

Results:

Six studies were included, involving 633 women diagnosed with PCOS. Supplementation of
vitamin D with metformin could have a significant impact on the improvement of menstrual cycles
compared to receiving metformin alone (OR = 2.11, 95% CI, 1.40- 3.19). There was no evidence of
heterogeneity across included studies. Subgroup analysis showed that the magnitude of the association
increased when only infertile women with PCOS were included (OR = 2.37, 95% CI, 1.52-3.72).

Conclusion:

This evidence suggests the possible benefit of adding vitamin D to metformin in regulating
the menstrual cycle among women with PCOS, especially infertile women.
MATLAB Simulation and Analysis of Effect of Stiffness to Damping Ratio and Variable Road Elevations on Vehicular Driving Comfort and Safety
Authors: Iskandarani Mahmoud Zaki
Published: November 2022

Background and Objective:

In this work, it is proposed that the use of variation in Tire Spring Length (Ls (Tire)), Suspension Spring Length (Ls (Suspension)) together with changes in Sprung Mass Acceleration (SMA), all as a function of Suspension Stiffness to Damping Ratio (k:c) and Road Elevation (E), will provide the required indicators to enable vehicle drive strategy and optimize autonomous vehicle automatic selection.

Methods:

MATLAB simulation is performed using three main k:c ratios (1, 20, 0.27) and three main road elevations (1, 3, 5) to achieve the stated objective of this work.

Results:

It is shown through this work that there is a relationship between spring length variation for both tire and suspension, road elevation, and sprung mass acceleration, such that driving strategy can be optimized according to road profile and k:c ratio using these parameters and the intersection of points between tire spring length variation and suspension spring length variation as a function of time and road elevation. Criteria are established in this research for the design and operation of driving strategy, such that three points of selection are used to enable either comfort or handling mode driving strategy.

Conclusion:

The final findings confirmed that for better handling, the Spring Length Variation Ratio (SLVR) should be less than one, with a steady increase in SMA and a minimum number of intersections between the tire spring length variation curve and suspension spring variation length curve as a function of road elevation and time. The presented work suggested through Tables 6 and 7 criteria to enable design for mode switching of autonomous vehicles as a function of road conditions.
Interventions Undertaken by the Parents in Managing their Youth Abusing Substances in Selected Hospitals, Limpopo Province, South Africa
Authors: Hlahla L.S. , Mothiba T. M.
Published: November 2022

Background:

Parents have a significant influence on managing and reducing the risk of substance abuse in the youth. Parents’ support and responsiveness to substance abuse progressively produce positive outcomes. They are driven by their parental instincts to help and protect their youth. Thus, when their youth abuse substances, they would do all they can to prevent the use of substances by their youth. They may use different methods to manage their youth before considering going to the hospital for help. This study investigated the interventions the parents use in managing their youth at home to make sure that they do not use the substances.

Methods:

A qualitative approach with the phenomenological design was adopted to explore parents’ intervention for youth abusing substances. Parents were purposively selected to participate in the study parents. Data collected through semi-structured interviews were analyzed using Tesch’s steps for qualitative data analysis.

Results:

Parents implemented various interventions to reduce and manage substance abuse in their youth. Some of the interventions included consultations with agents to assist their youth and raise awareness regarding substance abuse's dangers to their youth.

Conclusion:

The study findings have indicated that parents use various methods to ensure that their youth do not use substances. There is a need for regular meetings between parents and health care providers. It is recommended that parents consult with the health care providers on managing their youth abusing substances.
relevance of green branding on competitive strategies in service firms
Authors: Morka Ogor Tessy , Aliku Ifeanyi Harold
Published: November 2022

The study evaluated qualitatively the relevance of green branding in service firms.  Drawing the manufacturing industry perspective. Two objectives were drawn for this bordering on environmental actors and green innovation  as it affects competitive advantage, The extant literature revealed a strong impact of these predator variables on competitive advantage in service industry management. The findings was  that the performance of green innovation, product and process has a positive influence on the performance of the firms, although green innovation process is rarely discussed in the literature, it is very important to highlight the green innovation process, as it is easy to imitate the final product, compared to the process. Recommendations were made on the need to continue to uphold green innovation and major environmental factors to promote firm performance and profitability.