bluuebunny/crossref_metadata_2025 huggingface dataset:
OS USO DE PRECEDENTES COMO GARANTIA DA SEGURANÇA JURÍDICA NOS PROCESSOS ADMINISTRATIVOS
Authors: Braga Cristina Alves da Silva , França Vladimir da Rocha
Published: April 2023

O presente artigo tem como escopo analisar os impactos da ausência de precedentes administrativos no processo decisório frente ao princípio constitucional da segurança jurídica no sistema jurídico brasileiro. Para isso, analisa-se a incompatibilidade do teor das decisões com a norma constitucional e infraconstitucional vigente, através de uma metodologia de análise qualitativa com abordagem hipotético-dedutiva de caráter descritivo e analítico. Nesse contexto, objetiva-se discorrer sobre a necessidade da criação de parâmetros decisórios para resguardar um possível esvaziamento do texto constitucional decorrente da utilização de princípios como fundamento basilar de decisões.
SINUS LIFT COM USO DE BIOMATERIAL HA SINTÉTICO: RELATO DE CASO CLÍNICO
Authors: Oliveira Leonildo de Almeida
Published: April 2023

A reconstrução do processo alveolar na região posterior de maxila é muito frequente, para a reabilitação funcional e estética de pacientes edêntulos parciais ou totais com implantes dentários. E vem se tornando uma realidade cada vez mais segura, dessa forma, conhecer as características destes tecidos e biomateriais é fundamental para o sucesso. A maioria dos autores estudados relataram que o sucesso do Sinus lift com uso do biomaterial HA sintético na formação óssea é significativo, afirmaram ainda que nesses estudos houve formação de osso novo com largas lacunas de osteócitos rodeadas por partículas de HA e várias células multinucleadas foram encontradas nas superfícies das partículas da mesma. Podemos concluir que, conforme autores pesquisados, existe uma alta taxa de sucesso de osteointegração dos implantes com uso do biomaterial HA sintético como enxertia em seio maxilar. No entanto, alguns critérios para a obtenção de enxertos com alta previsibilidade de sucesso devem ser observados, tais como: capacidade de produzir osso por proliferação celular de osteoblastos viáveis transplantados ou por osteocondução das células ao longo da superfície enxertada, capacidade de formação óssea pela  células mesenquimais recrutada, remodelação do osso inicialmente formado no osso lamelar maduro, manutenção do osso maduro sem perda ao longo da função, capacidade de estabilizar implantes quando colocados simultaneamente com o enxerto, baixo risco de infecção, facilidade de aquisição, baixa antigenicidade e alto nível de segurança. Constatou-se que característica mais importante da hidroxiapatita seja a osteocondutividade, a qual induz crescimento ósseo no interior do enxerto, promovendo a estabilidade e manutenção do volume do implante.
DA INCONSTITUCIONALIDADE DA IMPOSIÇÃO DO REGIME DA SEPARAÇÃO DE BENS AO MAIOR DE 70 ANOS
Authors: Araújo Júnior João Batista de
Published: April 2023

O casamento é uma instituição que tem todas as regras já estão prontas, ou seja, os direitos e obrigações estão previamente estabelecidos que, em razão da característica da incondicionalidade que possui o casamento, não podem os nubentes antes de casar alterar essas regras. Uma das poucas matérias no casamento, que a legislação permite a vontade dos nubentes imperar, é em relação ao direito patrimonial no casamento.    Todavia, existem situações em que a lei proíbe essa escolha e, uma delas é o casamento do maior de 70 anos  que é obrigado a casar pelo regime da Separação Obrigatória de bens. Esse artigo analisar essa intervenção na vontade do idoso.
CONSEQUÊNCIAS DA POLIFARMÁCIA NA QUALIDADE DE VIDA DOS PACIENTES GERIÁTRICOS
Authors: Anderi Stephanie , Oliveira Caio Amaral , Oliveira Gabriela Alves Leite da Luz , Penedo Mariana Moreira , Gonçalves Matheus Hybner , Figueiredo Júnior Hélcio Serpa de
Published: April 2023

Polifarmácia é o termo no qual o indivíduo faz uso de cinco ou mais medicamentos concomitantemente. O uso de multimedicamentos pode trazer mais malefícios do que benefícios se não analisado rigorosamente todas as medicações, o paciente idoso pode desencadear maiores problemas, não só fisiológicos, mas também rotineiros, afetando diretamente na sua qualidade de vida. O objetivo desta revisão integrativa foi analisar a consequência que a polifarmácia afeta na qualidade de vida de pacientes geriátricos. Foram feitas buscas por artigos já existentes nas seguintes plataformas PubMed e Lilacs, sendo um total de 25 artigos incluídos após aplicação de critérios de inclusão e exclusão.  De acordo com a revisão, observou-se que o maior impacto do uso de cinco ou mais medicamentos seria o risco aumentado de interações medicamentosas. Diante dos estudos analisados consideramos também que idosos no qual possuem menos condições financeiras estão mais propensos a tomar mais medicamentos, e que pacientes com multimorbidades estão mais susceptíveis a fazerem interações medicamentosas. Por fim, foi evidenciado que o médico ao prescrever medicamentos deve ter uma atenção maior para não supermedicar o paciente idoso e levá-lo a possíveis problemas maiores dos já existentes.
POLÍTICAS PÚBLICAS DE AGRICULTURA FAMILIAR: CONTEXTO E INFLUÊNCIA DO PROGRAMA NACIONAL DE ALIMENTAÇÃO ESCOLAR (PNAE) E DO BOLSA FAMÍLIA
Authors: Pordeus Marcel Pereira , Rolim Francisca Alynne Ribeiro , Nunes Katianne Jamilia Oliveira , Caetano Wildeson de Sousa , Pordeus Caio Leonam Vieira , Alves Sidrack Rack Moraes , Silva Eduardo Diniz Sousa e , Araújo Adriana Muniz
Published: April 2023

Este artigo tem por foco o contexto do PNAE – Programa Nacional de Alimentação Escolar e o Bolsa Família na agricultura familiar e, tendo por população os filhos de agricultores que moram e trabalham na zona rural. Desse fato, este estudo problematiza a conjuntura das políticas públicas para a agricultura e sua influência na manutenção das condições básicas de vida para alunos e população em geral. Para tanto, o combate à fome com políticas sociais, a exemplo do Programa Brasil Sem Miséria, fomentam aspectos para subsistência e qualidade mínima de vida aos alunos e pais de família. Nesse viés, abranger a significância desta temática, fomenta a discussão e propõe reflexão nos aspectos inerentes às políticas públicas, seus embates e as resoluções que delas acompanham.
OS EFEITOS DA MUSICOTERAPIA NO TRATAMENTO ONCOLÓGICO INFANTO-JUVENIL EM AMBIENTE HOSPITALAR
Authors: Vasconcelos Wislen Paiva de , Rocha André Sousa , Khouri Mauro Michel El , Mesquita Antônia Juliana Ferreira
Published: April 2023

A temática investigada tem como ênfase os aspectos terapêuticos da música assim como os efeitos terapêuticos ofertados para a promoção do bem-estar e manejo da dor dos pacientes em tratamento oncológico infanto-juvenil. Objetivou-se analisar quais os efeitos terapêuticos da musicoterapia em ambiente hospitalar da oncologia infanto-juvenil. Trata-se de um estudo bibliográfico, do tipo revisão integrativa de literatura. Para sua execução, foram definidas quatro etapas operacionais descritas na literatura. Elaborou-se a seguinte questão norteadora: Quais os efeitos terapêuticos da musicoterapia no tratamento da oncologia infanto-juvenil em ambiente hospitalar? A busca foi realizada nos meses de setembro, outubro e novembro de 2022, a partir das bibliotecas e bases de dados: Biblioteca Virtual em Saúde – (BVS), Brazilian Journal of Health Review – BJHR, União Brasileira das Associações de Musicoterapia - UBAM –, Brazilian Journal of Music Therapy (BRjmt) Revista Brasileira de Musicoterapia, Scientific Eletronic Libraly Online (SciELO), Periódicos Eletrônicos em Psicologia (PEPSIC) e United State National Library of Medicine (MEDLINE) via BVS. Foram utilizados os descritores cadastrados nos Descritores em Ciências da Saúde (DeCS) e no National Library of Medicine (NIH) da Medical Subject Headgins (MESH) via PubMed: Musicoterapia; Oncologia; Hospital; MusicTherapy; Oncology; hospital. Para sua junção, fez-se uso do operador booleano “and”. Têm-se, então, dois artigos selecionados e tabulados, no período de 2014 a 2020, em distintos periódicos, que demonstram algumas características concernentes às investigações. Os resultados apontaram para o consenso de que a musicoterapia pode fazer parte do atendimento na pediatria oncológica nos hospitais como terapia alternativa e auxiliar para o manejo das dores. Portanto, é fato, que existe uma carência de musicoterapeutas, necessitando de mais cursos e especializações na área, para enfim ser vista como alternativa viável, a fim de que seja disponibilizada dentro das políticas públicas e dos equipamentos disponíveis pelo Estado.
PERFIL DE GESTANTES ASSISTIDAS NO PRÉ-NATAL EM UMA USF
Authors: Lima Severino Aguinaildo , Coutinho Diógenes José Gusmão
Published: April 2023

A gravidez pode ser o único contato que uma mulher em idade reprodutiva tem com os serviços de saúde, trata-se, portanto, de valiosa oportunidade para intervenções direcionadas à promoção da saúde da mulher como um todo. Acompanhar o desenvolvimento do bebê durante os nove longos meses de gestação é maravilhoso, nenhuma invenção do ser humano, por mais completa e evoluída que seja, chega aos pés da magia que é o encontro de duas células num ambiente propício a formar um novo ser completinho, pronto para chorar e mamar. Esse estudo tem como objetivo descrever um estudo do tipo descritivo transversal quantitativo sobre o Pré-natal e os cuidados que uma mulher deve ter durante a gestação. A análise dos resultados aqui apresentados corresponde ao levantamento realizado as 121 gestantes entre ano de 2015 a 2016 no PSF “X”. Assim como objetiva identificar o perfil socioeconômico e demográfico das gestantes atendidas na USF. A assistência à gestante necessita de total atenção por parte dos profissionais de saúde e dos que elaboram políticas públicas de saúde. Do total das 121 gestantes avaliadas, dentre essas gestantes 28% eram adolescentes até 20 anos. Entre essas 34 gestantes menores de 20 anos, 13 gestantes tinham menos de 16 anos, consideradas de risco pelo Ministério da Saúde. Os dados foram coletados através de um questionário semi-estruturado. Na análise dos dados verificou-se que 100% dos enfermeiros afirmam que os recém-nascidos sentem dor, sendo ela avaliada por meio de alterações fisiológicas, comportamentais e emocionais, porém apenas 7% afirmam fazer uso de escalas multidimensional. O pré-natal é a assistência que se dá à mulher a partir do momento em que ela descobriu que está gravida, o médico ou Enfermeiro procuram assistir e se preciso for, diagnosticar e tratar doenças preexistentes ou desenvolvida durante o Pre natal, oportunizando realização de um diagnóstico precoce de qualquer alteração tanto da mãe quanto do feto para que dentro das possibilidades existentes hoje elas possam ser corrigidas.
TRANSMISSÃO VERTICAL DO HIV - ANÁLISE DO CONHECIMENTO DOS ENFERMEIROS DO MUNICÍPIO SALINAS DA MARGARIDA – BA
Authors: Rosario Vivian Santana do , Rosario Nailton Roque Santana do
Published: April 2023

A síndrome da imunodeficiência adquirida (AIDS) consiste em um grande problema contemporâneo da saúde publica. Trazendo implicações para a sociedade e suas dimensões. No Brasil, de 2000 a 2014, foram notificadas 84.558 gestantes infectadas com o HIV, com maior índice nas regiões Sudeste (41,1%), Sul (31,1%) e Nordeste (15,4%). Como consequência percebesse um aumento do numero de casos de Transmissão vertical para HIV infantil. Denomina- se transmissão vertical (TV), situação na qual ocorre infecção do recém-nato durante a gestação, o parto ou por meio da amamentação. O enfermeiro é responsável por elaborar o plano de assistência de enfermagem na consulta de pré-natal, baseadas nas necessidades identificadas, priorizando-as, implantando as intervenções, fazendo orientações e encaminhamentos a outros serviços. Visando prestar a assistência de enfermagem e acompanhamento do pré-natal adequadamente, portanto Cabe ao enfermeiro, Realizar ações educativas do ponto de vista biológico para diagnosticar, prevenir e intervir precocemente junto às gestantes. A pesquisa foi realizada no município de salinas da margarida com os Enfermeiros das Unidades de Saúde da Família, com o intuito de investigar se esses profissionais seguiam as precauções universais do SUS para pacientes com HIV/AIDS. Se os mesmos obtinham conhecimento sobre as leis de amparo a criança e adolescente. Ficando evidente a necessidade de estes profissionais serem reclicados e buscarem novos conhecimentos a cerca do tema proposto. O presente estudo tratou acerca do conhecimento do profissional de enfermagem no direito do RN em não ser contaminado na amamentação de puerperais com HIV/AIDS, descrevendo as principais ações desenvolvidas pela enfermagem no âmbito de prevenir a transmissão vertical do vírus HIV da gestante para o RN, quais as medidas profiláticas a serem adotada pela equipe e procedimentos adequado, na busca de minimizar a contaminação do Vírus HIV para o RN. Enfocando o direito universal á vida e saúde com os princípios da equidade e a integralidade garantidos pelo sistema único de saúde (SUS) constituído pelo ECA.
APPROCHE PROXIMOLOGIQUE EN RÉANIMATION POLYVALENTE : NOTRE EXPÉRIENCE AU CENTRE MÉDICAL DIAMANT DE LUBUMBASHI (CMDL) / RDC
Authors: Christian Nantulu , Lucien Somwa Muhemedi , Evelyne Mputu Kalambayi , Kahambwe Kaya , Milinganyo Eddy Wasso , Mita Kasongo , Esther Onosomba Shako , Mshita Fahmi , Nurin Tajdin , Rosette Disashi , Nathy Lumbu , Patience Yandoli , Namegabe Franck Zirhumana , Panzu Patrick Muanda , Nsimire Berth Barhayiga , F R Iteke
Published: April 2023

Introduction : Le but est de montrer l’importance de l’intégration de cette approche dans notre environnement afin non seulement de redorer l’image de nos services de réanimation, mais aussi d’ajouter une autre dimension si importante dans la prise en charge des patients en état critique.

Méthodologie : Étude prospective à visée descriptive axée sur les données d’entretien entre le personnel soignant et les proches des patients admis au service de réanimation polyvalente du CMDL qui applique depuis 12 mois une approche de prise en charge psychosociale des patients graves. Etaient inclus, 3 parents désignés par le patient ou la famille en cas d’inconscience de ce dernier ou pour d’autres raisons personnelles.                                                                                  La collecte des données étaient faites directement à l’aide d’un questionnaire pré établi regroupant les items de l’approche psychosociale du service, analysé et traité par Excel 2016.

Résultats : 90 proches avaient participé à nos entretiens en raison de 3 proches au moins par famille de 1er, 2 ème, et 3 ème degré. L’âge moyen était de 43 ± 15,4 ans, avec un Sex Ratio de 1,7.                                                                                             Parmi les principaux éléments de perception négative : L’admission d’un parent reste l’objet de fatalité (39%) ; la restriction des visites (66%) ; le refus des soins (7 %). Par contre, les principaux éléments de perception positive ressortent : L’importance de l’annonce du pronostic basée sur les scores validés (97%) ; l’emplacement du service ne l’isolant pas véritablement d’autres services (97%) ; ainsi que les réunions biquotidiennes de briefing sur l’évolution quotidienne de leurs parents (100   Le niveau de satisfaction globale de cette approche ressentie par les proches est de 98,4%. Certaines raisons expliquant le manque des maximas sont : le refus personnel de voir son parent en état critique, la peur d’une fausse route lors de  l’alimentation d’un proche, ainsi que la pudeur de participer au bain d’un parent et les horaires contraignants. 

Conclusion : Ce travail montre une importance capitale de cette approche médico -psychosociale améliorant sensiblement la perception des proches dont les parents sont en état critique, diminuant de surcroît leur stress, et rapprochant d’avantage le patient de son entourage malgré la gravité de son état. D’autres approches sont nécessaires afin d’humaniser d’avantage les oins des patients en état critique témoignés par leurs proches
Pola Asuh Orangtua dalam Meningkatkan Perkembangan Bahasa Anak Usia Dini
Authors: Winarsih Yayuk , Lenny Lelly , Susanti Ni Putu Ari Dessy Ari , Yunitasari Septiyani Endang
Published: April 2023

Penelitian ini di latar belakangi oleh kondisi siswa TKIT Bunga Mufiidah yang mengalami keterlambatan bicara dan bahasanya. Tujuan dari penelitian ini adalah untuk menelaah dan mendeskripsikan pola asuh yang dapat meningkatkan perkembangan bicara dan bahasa anak dari pola asuh orangtua yang permisif dan pola asuh orangtua yang demokratis. Penelitian ini menggunakan metode kualitatif studi kasus. Pengumpulan data dilakukan melalui metode observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa pola asuh demokratis dapat meningkatkan perbendaharaan kosa kata/bahasa anak, sehingga anak mampu berbicara dan berkomunikasi sederhana dengan teman sebayanya, gurunya, dan orangtua di rumah.
A Study of College English Writing Teaching Based on Dynamic Assessment
Authors: SUN YAJIE
Published: April 2023

For a long time, college-level English writing teaching in China has relied mainly on summative tests, which provide a single and rigid evaluation criteria and limit students' all-around development of writing ability. However, with the current reform of college English teaching, the single assessment method cannot cater to the changing needs of the new teaching model, which emphasizes the cultivation of students' ability to use language. To address this issue, this paper proposes introducing the notion of dynamic assessment into English writing classes at the college level. Dynamic assessment emphasizes the assessment of the learning process and feedback of teaching information, which can lead to a comprehensive, scientific, and reasonable assessment system that plays a crucial role in realizing teaching objectives. Based on Vygotsky's sociocultural theory of mind, this paper presents scaffolding strategies for each stage of writing in college English writing teaching and learning. These strategies serve as a foundation for constructing a theoretical dynamic assessment model in Chinese non-English majors' writing classes. By introducing dynamic assessment into college English writing teaching, this paper aims to explore new methods that increase the efficiency of college English writing teaching and promote college students' English writing ability to adapt to the reform of new requirements for college English teaching.
Financial Flexibility and Investment Efficiency
Authors: SUN SISI
Published: April 2023

In recent years, the external financing environment of enterprises has deteriorated, especially since the impact of the COVID-19 epidemic, which has further limited external financing opportunities for enterprises. Therefore, it is imperative to adopt effective financial strategies to promote enterprise growth. This paper examines the influence mechanism of financial flexibility on the investment efficiency of new generation listed companies in the information technology industry from 2017 to 2020. Using the adjustment path analysis method, the paper constructs and verifies the role path of "financial flexibility → investment efficiency" to explore the impact of financial flexibility on investment efficiency and its effect on enterprise growth. The status quo of financial flexibility and investment efficiency of listed companies in the new generation of information technology industry is analyzed descriptively using stata16.0 statistical software. The paper proposes a hypothesis and constructs a multiple linear regression model to examine the influence of financial flexibility on investment efficiency. The empirical results show that the new generation of IT enterprises face challenges such as low capital flexibility and investment efficiency, particularly insufficient investment. Financial flexibility can help enterprises cope with capital demands under uncertain circumstances and improve the efficiency of enterprise investment. Therefore, in the market environment, enterprises should retain financial flexibility while strengthening internal control to improve investment efficiency and meet the needs of enterprise growth. The government and financial sector should promote supply-side structural reform in the financial sector, raise the level of regional financial development, and provide a favorable environment for external financing of strategic emerging industries such as the next-generation information technology industry.
How Efficiently Can Infant Stock Markets Exhibit the Random Walk? Evidence From Malawi
Authors: Chunga Joseph Paul , Ping Yu
Published: April 2023

It is no secret that the Malawi Stock Exchange (MSE) is still in its infancy. In 2011, the Malawi government in conjunction with the World Bank launched the Financial Sector Technical Assistance Project (FSTAP). The project targeted an improvement in financial literacy and also the automation of trading on the MSE to an advanced stage so as to improve market efficiency. This paper investigated the weak form and semi-strong efficient market hypotheses on the Malawi Stock Market in the wake of such a project with aid of parametric and non-parametric tests. The weak form efficiency of the market is tested by the application of Lo and MacKinlay’s Variance ratio test, the Cumby-Huizinga autocorrelation test and the Phillips-Perron unit root test. An adjustment to the methodology suggested by Borges (2009) is employed to ascertain the presence of market anomalies and by extension test out semi-strong form of efficiency. The paper employed more recent and comprehensive data stretching back to January 2010 through to June, 2022, amounting to 12years and 6months. Results are in support of weak form efficiency. However, the paper found significant evidence against semi-strong efficiency of the MSE. Calendar effects like day-of-the-week effect and turn-of-the-year effect were deemed to be absent from the market but turn-of-the-month effect was existent. Results of applying the Fama and French three-factor model to a time series regression reveal the presence of size and value effects. As such, the paper concludes that the Malawi Stock Market is weak-form efficient but semi-strong inefficient.
Analisis Kelayakan Usaha Setia Coffee
Authors: Zannibar Faisal Abi , Suliawati Suliawati , Arfah Mahrani
Published: April 2023

Tren minuman yang berbahan dasar kopi dan varian kopi dari bebagai jenis merek atau brand sangat diminati oleh semua kalangan mulai dari anak anak hingga orang dewasa. Hal ini dikarenakan Indonesia merupakan salah satu negara dengan tingkat konsumsi kopi tertinggi di dunia. Kota medan salah satu kota dengan jumlah penduduk terpadat ke tiga di indonesia oleh karena itu gerai atau coffee shop juga menjamur di kota ini. Dengan begitu membuka usaha dengan menyajikan menu utama coffee dengan keunikannya akan sangat laris di pasar, jumlah konsumen coffee sangat banyak agar dapat memenuhi permintaan konsumsi kopi yang semakin tinggi maka pengusaha memerlukan jenis usaha coffee shop dengan konsep yang berbeda untuk menarik perhatian serta ciri khas tersendiri dari usahanya. Untuk menarik pelanggan, usaha ini berada dijalan setia luhur kota medan, kecamatan medan helvetia. Dalam penelitian ini dilakukan analisis kelayakan usaha terhadap perancangan atau kelayakan usaha coffee yang diberi nama setia coffee berdasarkan aspek finansialnya apakah layak untuk dilanjutkan dengan begitu akan dicari berapa lama priode pengembalian modal, Probability Index tingkat pertumbuhan IRR, dan hasil penelitian ini menunjukkan bahwa payback periode usaha ini adalah 3 tahun, probability index (2,66) dan tingkat pertumbuhan IRR adalah 24,05% . dan usaha ini dinyatakan layak untuk dijalankan atau dilanjutkan.
Klasterisasi Penyakit HIV/AIDS di Jawa Barat Menggunakan Algoritma K-Means Clustering
Authors: Rosida Wina , Wijaya Yudhistira Arie
Published: April 2023

HIV (Human Immunodeficiency Virus) adalah virus yang menyerang system kekebalan tubuh  yang dapat melemahkan kemampuan tubuh melawan infeksi dan penyakit. Sedangkan AIDS (Acquired Immune Deficiency Syndrome) adalah kondisi di mana HIV sudah pada tahap infeksi akhir. Prevalensi kasus HIV/AIDS masih menjadi masalah kesehatan di Indonesia. Pada tahun 2017 angka tertinggi infeksi HIV/AIDS di Indonesia yaitu di DKI Jakarta (46.378 orang), diikuti Jawa Timur (33.043 orang), Papua (25.586 orang), Jawa Barat (24.650 orang), dan Jawa Tengah (18.038 orang). Secara nasional, Jawa Barat masih termasuk kedalam empat provinsi dengan kasus HIV/AIDS tertinggi. Hal ini menunjukan bahwa HIV/AIDS sudah menjadi ancaman bagi masyarakat luas karena selain mengancam nyawa penderitanya, penyakit ini berisiko terhadap penularan yang akan semakin meneingkat. Meningkatnya kasus HIV/AIDS dapat menjadi masalah dalam kejiwaan penderitanya, karena penyakit ini dapat menimbulkan dampak negative berupa masalah fisik, psikologis, sosial dan spiritual yang menyebabkan ODHA (Orang dengan HIV AIDS) menjalani kehidupan dengan penuh tekanan. Dalam penelitian ini dilakukan perhitungan menggunakan algoritma K-Means dengan Optimize Parameters Grid pada data kasus penyebaran HIV/AIDS pada tahun 2019-2021 bersumber dari Dinas Kesehatan Provinsi Jawa Barat. K-Means merupakan salah satu algoritma dalam data mining yang bisa digunakan untuk pengelompokan/clustering suatu data. Adapun data yang digunakan dalam penelitian ini sebanyak 971 record. Tujuan penelitian ini dilakukan untuk mengetahui cluster dari penyebaran penyakit HIV/AIDS sebagai salah satu upaya untuk membantu pemerintah dalam menekan angka kasus HIV/AIDS di provinsi Jawa Barat.
The Concept of Social Entrepreneurship as a Form of Social Motives and Career Paths according to a Psychosocial Perspective
Authors: Yulianah
Published: April 2023

The notion of social entrepreneurship can offer answers to social problems prevalent in today's society, particularly in entrepreneurship and social innovation. The idea of social entrepreneurship is a brand-new and interesting research area that piques the interest of the vast majority of scholars currently working in the field. In the context of social entrepreneurship, this review aims to isolate pertinent research issues in social psychology. This investigation takes a qualitative approach and makes use of descriptive research tools. Due to the many investigative research, individual qualities, societal motivations, and a specific vocational identity were some of the possible psychosocial elements discovered necessary for this sort of entrepreneurship. In addition, various perspectives on society, organizational goals, and psychosocial aspects of organizational behaviour were incorporated.
Reverse and Green Logistics Implementation for Sewage Treatment Plant Installation of “BELLA” Apartment Building
Authors: Rivaldy M. Labib , Dian Sua Pratama Bayu
Published: April 2023

Industrial and household operations mostly produce liquid waste that can harm the environment without further processing or processing. "Bella" Apartment is an apartment building located in one of the big cities in Indonesia, called Surabaya. The waste generated from this building comes from household activities such as toilet waste, laundry waste and kitchen waste. The purpose of this study is to minimize costs and increase the income of business owner.  This study used a qualitative descriptive method with 3 informants.  Based on financial analysis over the past 12 months, the management often complains about the high consumption of water so that the total cost of water paid to the water provider becomes higher and the owner's concern for the environment. water used in public facilities is taken from water sources for washing vehicles, washing clothes and other activities. In this study, the design of the Sewage Treatment Plant will be carried out, calculating the installation costs, the savings that can be obtained so that it can increase revenue, how to process secondary waste and maintenance from the sewage treatment plant, and the implementation of the Reverse Logistics concept in handling waste.  Reduce the amount of operating costs from electricity and Water costs to increase revenue.
Increasing the Potential of Tourism Destinations Through Combining the Principles of Sustainability and Innovation
Authors: Aziza Ismatillaevna Fayzieva , Dian Sua Pratama Bayu , Elya Rohimi Upit
Published: April 2023

The COVID-19 pandemic has had a significant impact on the tourism industry worldwide. Many countries are experiencing significant declines in tourist numbers and tourism revenues. The purpose of this study is to analyze the increase in the potential of tourism destinations through the combination of sustainable principles and innovation. This research is qualitative research carried out using the literature review method by searching for secondary information from various websites that are searched via the internet. In order to increase the potential of tourism destinations through combining the principles of sustainability and innovation, it is important to consider and promote environmental and social sustainability, as well as preserving local cultural heritage. This can help create tourism that is sustainable and profitable for all parties involved, including local communities, tourists, and the environment. Combining the principles of sustainability and innovation can increase the potential of tourism destinations. This research has the implication that by considering sustainable and innovative aspects in the development of tourist destinations, this research provides insight into how the application of sustainable principles and innovation can increase the attractiveness, sustainability, and success of tourist destinations.
Capital Market Reactions to The Covid 19 Pandemic
Authors: Umayi Ananda Woro , Gursida Hari , Indrayono Yohanes
Published: April 2023

This study aims to determine and analyze the capital market's reaction to the Covid 19 Pandemic in biotechnology companies listed on the Nasdaq. The method used in this study uses a type of quantitative method. This study uses an event study. The sampling method in this study was carried out using a non-probability random sampling approach. The announcement of the COVID-19 pandemic by the WHO and the commitment to produce a COVID-19 vaccine have had a significant impact on abnormal stock returns and trading volume activities of biotech companies listed on the NASDAQ stock market. However, there is no significant effect on the liquidity of biotech company stocks. In addition, the announcement of the COVID-19 pandemic also affected the volatility of biotech company stocks. In contrast, the announcement of a commitment to producing a COVID-19 vaccine did not significantly impact the volatility of biotech company stocks. So, it shows that the NASDAQ stock market reacts sensitively to announcements about the COVID-19 pandemic and efforts to produce COVID-19 vaccines by biotech companies. This shows that the COVID-19 pandemic has significantly impacted the stock market, especially in the biotechnology sector. The event study approach is used to test the market with a semi-strong form of market efficiency by demonstrating that the stock price reflects all published information (all publicly available information).
Kehidupan Spiritual Lansia di Lembaga Sosial Cinta Ibu Tresna Werdha di Nagari Cubadak Kabupaten Lima Kaum Batu
Authors: Zunnuraini Rezni , Afrinaldi Afrinaldi , M Iswantir , Yarni Linda
Published: April 2023

This research departs from the theory which suggests that religious spirituality increases in the elderly, namely by increasing religious activities and activities, such as participating in recitations. Apart from preparing themselves to face death, this is also done by the elderly to discover the meaning and importance of life. According to Danah Zohar and Ian Marshall, spiritual comes from the Latin word Spiritus which means something that gives life or vitality to a system. Spiritual religion as one of the foundations that must be owned by every human being in order to make the soul as an insanul kamil in the context of life in accordance with the shari'ah that has been determined by Allah SWT so that the soul is maintained in a state of nature and purity. While what is meant by old age is the age that is approaching the end of the human life cycle in the world. Age in this stage starts from the 60's until the end of life. This stage where aging and decline occur in the form of cumulative changes in living things, including the body, tissues and cells that experience a decrease in capacity.This research was conducted through a qualitative descriptive method, namely a method that gives a systematic description of the situation that occurred in the field. The key informants are the elderly who are in PSTWKSI, and the supporting informants in this study are elderly caregivers. In collecting the data needed, the authors carried out interviews with key informants and supporting informants, as well as to corroborate statements from informants, the authors also made observations. Then the data that has been obtained will be processed using descriptive analysis techniques.Based on the results of this study, it was found how the religious spiritual life of the elderly in the aspects of obligatory and sunnah observance of elderly worship performed together (in congregation) or alone is quite good. Discipline of the elderly in doing the tasks that have been set or by doing it because of their own desires is also quite good. The honesty of the elderly to the people around them is not good, such as to their friends or to caregivers. And the caring attitude towards the elderly in PSTWKSI is quite good.
Students’ Perception on the Using of Google Translate in Translation Class at the 4th Semester of English Departemet of UIN Sjech M. Djamil Djambek Bukittinggi
Authors: Febyola Febyola , Eliza Eliza , Reflinda Reflinda , Roza Veni
Published: April 2023

The using of Google Translate in translation class has been an issue whether it has to be avoided or not. The problem of this research was different perceptions among English students about the using of Google Translate in translation class. The purpose of this research was to find out students’ perception on the using of Google Translate in translation class based on cognitive, affective, and connative aspect. This research used a quantitative approach witha survey design. The population of this study were the students who had taken translation class at the fourth semester of English Departement in academic year 2021/2022 consisting of 37 students from 4 classes. The researcher used total sampling because the population are less than 100 students. Instrument of this research was questionnaire which consisted of 30 items. The researcher did the validity instrument through three experts. In analyzing the data, the researcher used quantitative descriptive analysis. Total percentage of data analysis was 67.07% for cognitive aspect, 69.77% for affective aspect, 57.99% for connative aspect. The average of three percentage was 64.94%. This percentage was good criteria. It means that the perception of the students was good. Thus, the result of the research showed that students who had taken translationclass dominantly agree the use of Google Translate in translation class.
EUROPEAN LEGAL FRAMEWORK OF RURAL DEVELOPMENT POLICY
Authors: Maksimović Sekulić Nina , Vujić Tamara , Stankovic Milan
Published: April 2023

New social demands, opportunities in the green economy, opportunities opened up by digital technology, and the consequences of the COVID-19 pandemic and the spread of remote work have again drawn attention to rural areas. In 2020, the European Commission conducted a public consultation on the long-term vision for rural areas. Support for rural areas is already provided under several EU policies, which contributes to their balanced, fair, green and innovative development. To support the implementation of the action plan, the common agricultural policy (CAP) and the cohesion policy will be of particular importance, which will be accompanied by a whole range of policies from other areas.The aim of this paper is an analysis of the EU legal framework of rural development policy, together with an analysis of the further development of the LEADER approach. Finally, a special focus is placed on the analysis of documents (long-term vision for the EU’s rural areas) that deal with the future of rural development in the EU.
Adaptive neural network observer‐based filtered backstepping control for nonlinear systems with fuzzy dead‐zone and uncertainty
Authors: Shahriari‐kahkeshi Maryam , Jahangiri‐heidari Mohsen , Shi Peng
Published: April 2023

This study proposes a high gain observer‐based filtered backstepping control scheme for nonlinear systems with unknown dynamics and dead‐zone constraint. Majority of the previously papers describe dead‐zone by the conventional certain models, assume that all state variables are available and invoke the backstepping or conventional dynamic surface control (CDSC) approaches for controller design. This work describes the dead‐zone by the fuzzy model, invokes radial basis function neural network (RBFNN) to model the unknown functions and proposes a RBFNN‐based high gain observer to estimate unmeasurable states. To avoid the complexity explosion in the backstepping approach and eliminate the sensitivity to the time‐constant of the first‐order filters in the CDSC, a nonlinear tracking differentiator (NTD) with finite time convergence property is used instead of the first‐order filters in the CDSC to obtain derivative of the virtual inputs. Moreover, the error compensation mechanism and auxiliary signal are proposed to eliminate the influence of the filtering error and input nonlinearity, respectively. Despite the fuzzy dead‐zone, the proposed scheme makes the closed‐loop signals uniformly ultimately bounded. In comparison with the existing results, (i) some assumptions like certain model of dead‐zone and full state measurement are removed, (ii) “explosion of complexity” and sensitivity to the time constant of the first‐order filters are eliminated, (iii) effect of the filtering error and input nonlinearity are compensated, (iv) number of adjustable parameters and online computational burden are decreased effectively. Simulation results on the two well‐known examples verify the effectiveness and applicability of the proposed new design technique.
Single‐Orientation Epitaxy of Quasi‐1D Tellurium Nanowires on M‐Plane Sapphire for Highly Uniform Polarization Sensitive Short‐Wave Infrared Photodetection
Authors: Wei Xin , Wang Shiyao , Zhang Nannan , Li Yubin , Tang Yue , Jing Hongmei , Lu Jiangbo , Xu Zhuo , Xu Hua
Published: April 2023

Tellurium (Te), an elemental van der Waals semiconductor, has intriguing anisotropic physical properties owing to its inherent quais‐1D crystal structure. Synthesizing ultrathin Te crystal with uniform orientation is important to its large‐scale device applications, but that remains a great challenge. Herein, the nanoscale grooves‐induced unidirectional epitaxy growth of 1D Te nanowires via physical vapor deposition on the annealed m‐plane sapphire is demonstrated. By enhancing the annealing temperature from 1000 to 1300 °C, nanoscale grooves on m‐plane sapphire arising along the [100] direction and gradually distinct, and the corresponding Te nanowires grown on them turns from random to uniform, finally achieving nearly 95% unidirectional Te nanowires. The as‐grown Te nanowires possess high crystallinity with clearly chiral helical chains along the c‐axis direction and reveal thickness‐tunable bandgap with prominent linear‐dichroic. As results, the Te nanowire‐based photodetectors demonstrate a broadband photoresponse from visible (532 nm) to short‐wave infrared (2530 nm), with high responsivity of 327 A W−1 as well as strong and uniform polarization sensitivity (anisotropic ratio = 2.05) to 1550 nm light. The high crystallinity and superior anisotropy of Te nanowires, combined with the orientation‐controlled preparation endows it with great feasibility for constructing chip‐scale multifunctional optoelectronic devices.
Multichannel Single‐Photon Emissions with On‐Demand Momentums by Using Anisotropic Quantum Metasurfaces
Authors: Jia Shangtong , Li Yongkang , Xue Zeyang , Chen Kangyao , Li Zhi , Gong Qihuang , Chen Jianjun
Published: April 2023

Photon momentums and their control are important for carrying quantum information and increasing information capacities. It is a great challenge to freely control multiple momentums of single photons based on only phase‐dependent schemes in isotropic metasurfaces because exact manipulations of interference phases and precise alignments between quantum emitters and metasurfaces are involved. Here, an anisotropic metasurface, in which anisotropic rather than isotropic nanoscatterers are arranged anisotropically, is proposed to freely control multiple momentums of single photons. In the metasurfaces, the phase‐independent and phase‐dependent schemes are used to independently control spin angular momentums (SAMs) and linear momentums (LMs), respectively. The phase‐independent scheme allows robust alignment between quantum emitters and metasurfaces. The anisotropic design amends geometrical phases for oblique emissions, providing larger ranges (up to 53°) for tailoring LMs. In experiments, three‐channel single‐photon emissions with independent SAMs and LMs are demonstrated. The introduction of anisotropic nanoscatterers and anisotropic arrangements of nanoscatterers is a more general design method for metasurfaces, and it could provide more flexibility to freely and efficiently tailor single‐photon emissions.
Palladium‐Percolated Networks Enabled by Low Loadings of Branched Nanorods for Enhanced H2 Separations
Authors: Hu Leiqing , Chen Kaiwen , Lee Won‐Il , Kisslinger Kim , Rumsey Clayton , Fan Shouhong , Bui Vinh T. , Esmaeili Narjes , Tran Thien , Ding Yifu , Trebbin Martin , Nam Chang‐Yong , Swihart Mark T. , Lin Haiqing
Published: April 2023

Nanoparticles (NPs) at high loadings are often used in mixed matrix membranes (MMMs) to improve gas separation properties, but they can lead to defects and poor processability that impede membrane fabrication. Herein, it is demonstrated that branched nanorods (NRs) with controlled aspect ratios can significantly reduce the required loading to achieve superior gas separation properties while maintaining excellent processability, as demonstrated by the dispersion of palladium (Pd) NRs in polybenzimidazole for H2/CO2 separation. Increasing the aspect ratio from 1 for NPs to 40 for NRs decreases the percolation threshold volume fraction by a factor of 30, from 0.35 to 0.011. An MMM with percolated networks formed by Pd NRs at a volume fraction of 0.039 exhibits H2 permeability of 110 Barrer and H2/CO2 selectivity of 31 when challenged with simulated syngas at 200 °C, surpassing Robeson's upper bound. This work highlights the advantage of NRs over NPs and nanowires and shows that right‐sizing nanofillers in MMMs is critical to construct highly sieving pathways at minimal loadings. This work paves the way for this general feature to be applied across materials systems for a variety of chemical separations.
Oral metagenomes from Native American Ancestors reveal distinct microbial lineages in the pre‐contact era
Authors: Honap Tanvi P. , Monroe Cara R. , Johnson Sarah J. , Jacobson David K. , Abin Christopher A. , Austin Rita M. , Sandberg Paul , Levine Marc , Sankaranarayanan Krithivasan , Lewis Cecil M.
Published: April 2023

Objectives

Limited studies have focused on how European contact and colonialism impacted Native American oral microbiomes, specifically, the diversity of commensal or opportunistically pathogenic oral microbes, which may be associated with oral diseases. Here, we studied the oral microbiomes of pre‐contact Wichita Ancestors, in partnership with the Descendant community, The Wichita and Affiliated Tribes, Oklahoma, USA.

Materials and Methods

Skeletal remains of 28 Wichita Ancestors from 20 archeological sites (dating approximately to 1250–1450 CE) were paleopathologically assessed for presence of dental calculus and oral disease. DNA was extracted from calculus, and partial uracil deglycosylase‐treated double‐stranded DNA libraries were shotgun‐sequenced using Illumina technology. DNA preservation was assessed, the microbial community was taxonomically profiled, and phylogenomic analyzes were conducted.

Results

Paleopathological analysis revealed signs of oral diseases such as caries and periodontitis. Calculus samples from 26 Ancestors yielded oral microbiomes with minimal extraneous contamination. Anaerolineaceae bacterium oral taxon 439 was found to be the most abundant bacterial species. Several Ancestors showed high abundance of bacteria typically associated with periodontitis such as Tannerella forsythia and Treponema denticola. Phylogenomic analyzes of Anaerolineaceae bacterium oral taxon 439 and T. forsythia revealed biogeographic structuring; strains present in the Wichita Ancestors clustered with strains from other pre‐contact Native Americans and were distinct from European and/or post‐contact American strains.

Discussion

We present the largest oral metagenome dataset from a pre‐contact Native American population and demonstrate the presence of distinct lineages of oral microbes specific to the pre‐contact Americas.
Preclinical characterization and IND‐enabling safety studies for PNT001, an antibody that recognizes cis‐pT231 tau
Authors: Foster Kelly , Manca Matteo , McClure Kim , Koivula Pyry , Trojanowski John Q. , Havas Daniel , Chancellor Sarah , Goldstein Lee , Brunden Kurt R. , Kraus Allison , Ahlijanian Michael K.
Published: April 2023

BACKGROUND

The cis‐conformer of tau phosphorylated at threonine‐231 (cis‐pT231 tau) is hypothesized to contribute to tauopathies. PNT001 is a humanized, monoclonal antibody that recognizes cis‐pT231 tau. PNT001 was characterized to assess clinical development readiness.

METHODS

Affinity and selectivity were assessed by surface plasmon resonance and enzyme‐linked immunosorbent assay. Immunohistochemistry (IHC) was performed with brain sections from human tauopathy patients and controls. Real‐time quaking‐induced conversion (RT‐QuIC) was used to assess whether PNT001 reduced tau seeds from Tg4510 transgenic mouse brain. Murine PNT001 was evaluated in vivo in the Tg4510 mouse.

RESULTS

The affinity of PNT001 for a cis‐pT231 peptide was 0.3 to 3 nM. IHC revealed neurofibrillary tangle‐like structures in tauopathy patients with no detectable staining in controls. Incubation of Tg4510 brain homogenates with PNT001 lowered seeding in RT‐QuIC. Multiple endpoints were improved in the Tg4510 mouse. No adverse findings attributable to PNT001 were detected in Good Laboratory Practice safety studies.

DISCUSSION

The data support clinical development of PNT001 in human tauopathies.