bluuebunny/crossref_metadata_2025 huggingface dataset:
A chat about sedentarism in adolescence
Authors: Silva Regina Márcia Ferreira , Felício Cinthia Maria , Ferreira Júlio César , Noll Matias
Published: November 2024

The research was conducted on students and the external community - people with no academic or functional ties to the Federal Institute of Goiás Câmpus Itumbiara, Brazil. As a remote, hour-long complementary activity, our aim was to perform an educational practice using active methodologies to deal with the concepts of integral human formation and understanding the importance of physical aspects as a part of it, and physical activity and inactivity in adolescence in the context of the COVID-19 quarantine period. The activity involved 22 participants, including technical course students integrated to high school and higher courses, and external community. The educational practice adopted two active methodologies (conversation circle and gamification) utilizing technology that enabled remote meetings (Google Meet). We suggest the use of conversation wheel and games to maintain a constant dialogue about physical inactivity, with adolescent population, for awareness about the harmful effects of physical inactivity.
A presença de mulheres na Educação Profissional e Tecnológica
Authors: Rocha Simone de Souza Silva , Mansur André Fernando Uébe , Prates Daniela medeiros de Azevedo
Published: November 2024

Neste artigo, analisa-se como se constituem as desigualdades de gênero entre as estudantes da Educação Profissional e Tecnológica de uma instituição de ensino brasileira. A coleta de dados realizou-se por meio de questionários e oficinas. Para a análise das informações, utilizou-se como base a técnica de Análise de conteúdo. Os resultados evidenciam que há desigualdade de gênero e preconceito em relação às mulheres em cursos técnicos integrados da unidade pesquisada. Constatou-se também que as estudantes pesquisadas estão passando por um processo de desconstrução social, em busca de equidade de gênero.
Pensamento computacional na formação de professores de matemática
Authors: Lacerda de Abrantes Maria Gracielly , Alves do Rego Barros Rafael José
Published: November 2024

No contexto das discussões sobre a incorporação do Pensamento Computacional (PC) na educação básica, um dos principais desafios atuais está na formação de professores que proporcione o desenvolvimento de atividades que sejam solucionadas utilizando as técnicas do PC. A Base Nacional Comum Curricular (BNCC) homologada em 2018, na área de matemática e suas tecnologias, aborda o pensamento computacional como mais um objeto do conhecimento a ser explorado por professores de matemática em suas aulas. Com isso, despertou a investigação deste estudo para uma análise curricular dos cursos de graduação em Matemática como forma de identificar se o currículo ofertava componentes curriculares na área da computação e se estas componentes apontavam elementos do pensamento computacional a ser desenvolvido habilidades inerentes a formação teórica e prática do professor de matemática. Os resultados apresentados estão no formato de quadros, a partir de uma análise documental dos projetos políticos de curso focando na grade curricular, deste modo, observa-se a necessidade de reformulação da grade curricular das graduações em Matemática em prol de atender a necessidade da Educação Básica com o pensamento computacional, além disso, uma definição consistente do Pensamento Computacional e sua aplicação para a resolução de problemas no ensino básico.
A produção científica sobre Educação Profissional e Tecnológica
Authors: Nascimento Fernando Honorato , Pereira Marlene de Paula
Published: November 2024

O objetivo deste trabalho foi quantificar e qualificar a produção científica relacionada à EPT, utilizando-se para tal a técnica de pesquisa denominada “Cienciometria”. Adotou-se como plataforma de pesquisa o banco de dados da Coleção Principal do Web of Science (WoS) e como marco temporal o período de 1945 a 2021. A busca foi realizada no mês de julho de 2022. Como resultado foram encontrados 885 documentos, publicados na Core Colection. Deste total, 51,64% são de artigos originais de pesquisa básica e/ou aplicada. Do total de artigos encontrados, 64 reportaram o Brasil como país de origem dos pesquisadores. Contudo, apenas 38 trataram especificamente sobre EPT. Conclui-se que é necessário o desenvolvimento e aplicação de pesquisas relativas a EPT, no mundo e, especialmente, no Brasil.
A microbiologia no currículo dos cursos de Ensino Médio Integrado dos Institutos Federais no Rio Grande do Sul
Authors: Wille Caroline Neugebauer , Escott Clarice Monteiro , Pizzato Michelle Camara
Published: November 2024

Considerando a relevância do ensino médio integrado e a importância da Microbiologia para a compreensão da realidade e a formação humana integral, o objetivo deste trabalho foi investigar como esse conteúdo é retratado nos currículos e o potencial impacto dessa abordagem na formação dos estudantes. Para tanto, foi realizada pesquisa documental abrangendo os IFs presentes no estado do Rio Grande do Sul, englobando Projetos Pedagógicos de Curso, ementas e planos de ensino, sendo os últimos avaliados segundo a Análise de Conteúdo. Constatou-se que, apesar do esforço em desenvolver os conteúdos de Microbiologia em uma perspectiva integrada, é necessário avançar nas práticas pedagógicas promovendo a compreensão da realidade em sua totalidade e superando dicotomias entre formação profissional e básica, teoria e prática.
Systematic Review of Gaps in Single Case Design Research: Evaluation of Study Quality and Rigor Using the Single Case Analysis and Review Framework
Authors: Elliott Tyler-Curtis , Ayres Kevin , Hart Joseph , Ledford Jennifer
Published: November 2024

As the use of single case research design (SCRD) to answer socially significant research questions increases, so too should the rigor and quality of those designs. Higher rigor and quality decreases the chance of threats to internal validity and increases the chance of replication, both of which are critical to determining the effectiveness of an intervention. We conducted a systematic review of systematic literature reviews (k =18) that scored the quality and rigor of SCRD papers using the Single Case Analysis and Review Framework (SCARF; Ledford et al., 2023). On a continuous rigor/quality scale of 0-4, the 1,251 articles in all included reviews obtained an average of 2.14 with a standard deviation of 0.62 suggesting large gaps in the rigor/quality of SCRD. We discuss the implications of these gaps and offer recommendations for researchers to increase the rigor and quality of their SCRD studies.
Connected Lives
Authors: Diamond Ruth
Published: November 2024

This is the third in a series of articles about women who played important roles leading to the founding of the American Center for the Alexander Technique (ACAT). The first article in this series, “Connected Lives,” AmSAT Journal, no. 17 (Fall 2020), was devoted to Ethel Webb, who taught in Alexander’s practice in New York from 1914 to 1922 and participated in the training of Frank Pierce Jones. The second article, “Margaret Naumburg and the Alexander Technique, Part 2,” AmSAT Journal, no. 18 (Spring 2021), focused on Naumburg’s introduction of the Technique into New York classrooms and the early history of the Alexander Technique in New York City. This article explores the life of Irene Tasker, who met Naumburg and Webb in Rome in 1913 at the first international Montessori Training. Tasker was F.M. Alexander’s assistant, and she and Webb edited Alexander’s books. She introduced the Technique into childhood education, and she was the first to teach it in a group, using everyday activities.
Expressive and apparent changes in law
Authors: Suska Marek
Published: November 2024

The types of changes in law specified in the theory and practice of interpretation have been analyzed in the article. So far, normative and explanatory changes have been specified therein; in the former the legislator’s goal is to change the scope of rights or obligations, in the latter – to improve the pragmatic features of the legal text. In the author’s opinion, the above typology does not provide a full picture of the goals for which changes in the law aremade. When reflecting on changes in law, one should notice their expressive and apparent aspects. Changing the law may be a way of expressing approval or disapproval of a certain state of affairs; it may also be merely a deception of public opinion regarding the solution of a certain problem. In addition to normative and explanatory changes, we can also distinguish expressive and apparent changes.
Impact assessment of draft regulation and consultation process
Authors: Grzelak-Bach Katarzyna
Published: November 2024

In a democracy, societal participation is crucial and can take various forms, one of which is the involvement of stakeholders in the legislative process. Projects subject to consultations should precisely define the impact of proposed regulations on citizens and the legal environment, as well as the anticipated costs and benefits. A key component of the consultation process is the precise presentation of analyses and data confirming the justification of the regulations, making the Regulatory Impact Assessment (RIA) form an essential element of the project justification. Such transparency allows for the shaping of public policies in a way that minimizes potential controversies and social discontent. The role of the Government Analysis Center, operating as one of the auxiliary bodies of the Prime Minister, is also to ensure coordination of the legislative activities of the Council of Ministers regarding prepared regulatory impact assessments. This entails verifying whether the obligation to subject the project to public consultations has been fulfilled and whether procedures and deadlines have been adhered to.
Common Turkic folk geographical terms of the Kyzylkum region
Authors:   South Kazakhstan University, Mingbaev Nurlan Zh. , Avdonin Vladimir V. ,   Tashenev University
Published: November 2024

The article deals with the general Turkic toponymy of the Kyzylkum region, in particular, the folk geographical terms present in the topography of this territory. Despite the harsh climatic conditions of the desert, this territory has been developed by man since ancient times, which proves the presence of historical toponyms and ethnonyms. The toponymy of the region is characterized by the active participation of various folk geographical terms in the structure of landscape names. Folk geographic terms kum, tau, bulak, kol, sai, aryk, kudyk, suat, ozen, keshu, oi, boget, ashy, kesik, and others were an inexhaustible source for designating orographic, hydrographic and other objects. The richness and diversity of the region’s toponymic system was directly related to the economic activities of its original inhabitants. Transhumance of the desert natives required a detailed knowledge of the features of the physical and geographical structure of their own habitat, taking into account the natural and climatic conditions and landscape specifics of the entire territory of animal pasturing, i.e. deserts, mountains, rivers, lakes, springs, watering holes, fords and crossings, as well as the exact language designation of these objects. Thus, economic activity contributed to the fact that a nomadic tribe knew its territory thoroughly, down to small objects, and created a developed toponymic system. The collected toponymic material is considered in the lexical-semantic, etymological and linguo-geographical aspects in order to identify specific units that are generally characteristic of common Turkic folk geographical terms. In the process of studying a number of oronyms, hydronyms, dromonyms, gephyronyms, it was established that, in this territory, despite the flatness of the terrain, there were many oronyms with components tau (mountain), tobe (hill). In addition, contrary to logic, a significant number of hydronyms was found in the desert with components, kudyk (well), suat (place of watering hole), bulak (spring). The term kesik, literally “cut”, which was used to designate barchans with sharp, as if cut edges that one can meet in the sandy desert, was described for the first time. Also, common Turkic structural formations were identified that arose according to the type: numeral + term. The use of sacred numerals in the structure of toponyms with folk geographical terms denoting the conditional meaning of plurality was established. In the etymological aspect, special attention was paid to the consideration of the dromonym Yassykeshu, which correlates with the name of the medieval polysonym Yassy, an important city on the segment of the Great Silk Road passing through Kyzylkum. Its scientific etymology has not yet received a positive decision.
A substantiated etymology was proposed, which allows to clarify the lost history of
origin and the obscured semantics of the polysonym Yassy.
Uso de redes sociais e saúde mental: um estudo qualitativo com adolescentes de Salvador e Região Metropolitana, Bahia
Authors: Santana Ramiro Rodrigues Coni , Dantas Bianca Alves , Costa Idylla Katheryn Santos , Conceição Luciana Guerra , De Lucena Thiago Viana , Casales Isabela da Silva
Published: November 2024

INTRODUÇÃO: Este estudo investigou como adolescentes da Região Metropolitana Salvador percebem as repercussões do uso de redes sociais em sua saúde mental. MÉTODO: Utilizou-se um desenho qualitativo, foram entrevistados 20 adolescentes, de 14 a 17 anos, sobre suas experiências com redes sociais como Facebook, Instagram e TikTok. RESULTADOS E DISCUSSÃO: Os dados indicam que o uso excessivo dessas plataformas está associado a problemas de saúde mental, como ansiedade, depressão e baixa autoestima. Os adolescentes relataram que a comparação social, especialmente em relação a padrões de beleza, impacta negativamente sua autoestima e pode levar a comportamentos autolesivos. A pandemia de COVID-19 intensificou o uso das redes, exacerbando problemas emocionais devido ao isolamento social. No entanto, atividades físicas e hobbies foram mencionados como estratégias para mitigar esses efeitos negativos. CONCLUSÕES: Conclui-se que, embora as redes sociais ofereçam benefícios, como acesso a informações sobre saúde mental, autocuidado e aprendizagem de temas variados, é crucial promover um uso consciente e equilibrado para proteger o bem-estar emocional dos adolescentes. Programas de conscientização e políticas públicas são necessários para educar sobre os impactos do uso prolongado das redes sociais e incentivar práticas mais saudáveis.
Nuclei Isolation and Clean-Up using GentleMACS and Anti-Nucleus Microbeads v1
Authors: Köchl Fabian
Published: November 2024

Obtaining a clean nuclei suspension for subsequent single-nuclei RNA sequencing can be challenging. Especially liver nuclei suspensions are prone to high ambient RNA content. Alternative nuclei clean up methods like Fluorescence-activated Cell Sorting can stress nuclei, decrease nuclei quality and are time consuming and need specialized equipment. To overcome these challenges we applied a simple protocol for isolating and cleaning up nuclei for single-nuclei RNA sequencing using the GentleMACS Octo dissociator coupled with anti-Nucleus microbeads cleanup. The following protocol has been successfully tested for Rat, Mouse and Minipig liver as well as Mouse brain.
Site-specific incorporation of BpF into ubiquitin-like proteins (UBLs) in E. coli v2
Authors: Sandy Zac
Published: November 2024

This protocol details the site-specific incorporation of BpF into ubiquitin-like proteins (UBLs) in E. coli. The use of a photo-crosslinkable residue within UBLs enhances the detection of weak and transient protein-protein interactions. This protocol provides a general workflow for the production of such protein probes, followed by methods to detect specific protein interactions using targeted or proteomic approaches. This protocol is linked to the PLOS ONE protocols manuscript "Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions".
Intraarticular injection of fast blue v1
Authors: Goodwin George , Denk Franziska
Published: November 2024

Protocol for injection of fast blue into the knee joint cavity for retrograde labelling of intraarticular afferents.
Phenol-chloroform extraction for museum hides using Phase lock gel v1
Authors: Vargas Karla
Published: November 2024

This protocol outlines a method for extracting high-quality DNA from museum-preserved hides using a phenol/chloroform extraction process and phase lock gel tubes to optimize yield and purity. The procedure involves a multi-step workflow beginning with ethanol soaking to remove salts, followed by mechanical homogenization and enzymatic digestion of the sample to release nucleic acids. DNA is then purified through successive rounds of phenol/chloroform extraction using phase lock gel to efficiently separate phases and minimize contamination. Precipitated DNA is pelleted, rinsed with ethanol, and air-dried before being resuspended in low TE buffer for downstream applications. This method is tailored for challenging archival specimens, ensuring maximum DNA recovery while minimizing degradation and contamination.
Group housed home cage monitoring for assessment of activity in mice v1
Authors: Goodwin George , Denk Franziska
Published: November 2024

This protocol describes how to use the home cage analyser developed by Actual Analytics to measure activity in group-housed mice.
Coletânea de estudos avançados em direito - Turma 2023: Programa de Pós-doutorado em Direito Instituiçoes e Negócios – PPGDIN – UFF
Authors: Martins Guilherme Magalhães
Published: November 2024

A Coordenação do Programa de Pós-graduação em Direito, Instituições e Negócios da Universidade Federal Fluminense – PPGDIN/UFF, tem a honra de apresentar a COLETÂNEA DE ESTUDOS AVANÇADOS DO PROGRAMA DE PÓS-DOUTORADO EM DIREITO INSTITUIÇOES E NEGÓCIOS – PPGDIN – UFF, obra jurídica fruto da pesquisa dos pós-doutorados, Nagib Slaib Filho, Irineu Carvalho de Oliveira Soares, Otto Gerstenberger Junior, Carla Izolda Fiuza Costa Marshall e Sidney Rosa da Silva Junior, além da contribuição do pós-doutorando Renato Cerceau.

O trabalho jurídico publicado envolve temas de relevância na sociedade contemporânea, como o capitulo BREVE HISTÓRIA DOS FUNDAMENTOS NORMATIVOS DAS CORTES CONSTITUCIONAIS, desenvolvido pelo Pesquisador Nagib Slaib Filho; o texto O DIREITO À IMPENHORABILIDADE DO BEM DE FAMÍLIA E A ANTINOMIA RELACIONADA AO FIADOR NOS CONTRATOS DE LOCAÇÃO COMERCIAL, desenvolvido pelo Pesquisador Irineu Carvalho De Oliveira Soares; a redação DIREITOS FUNDAMENTAIS DA EDUCAÇÃO: A EFETIVIDADE DOS PROGRAMAS PÚBLICOS EDUCACIONAIS ENTRE 2012 E 2022, escrito por Otto Guilherme Gerstenberger Junior; a contribuição O ESTADO DA ARTE DO MERCADO DE CRÉDITO DE CARBONO: PERSPECTIVA DE UMA ARQUITETURA REGULATÓRIA NO BRASIL, proposto por Carla Izolda Fiuza Costa Marshall e, o capítulo INDISPONIBILIDADE, INTERESSE PÚBLICO E LIMITES DO CONSENSO: NOVOS BALIZAMENTOS PARA UMA SOCIEDADE MODERNA, produzido por Sidney Rosa da Silva Junior. O livro consta ainda o capítulo APLICABILIDADE DO CÓDIGO DE DEFESA DO CONSUMIDOR NO MERCADO DE PLANOS DE SAÚDE, desenvolvido por Plinio Lacerda e por Renato Cerceau.

O PPGDIN agradece a todos o compartilhamento do conhecimento específico e pela contribuição cientifica inédita, que está sendo apresentado a comunidade acadêmica.
Breve história dos fundamentos normativos das cortes constitucionais
Authors: Slaibi Filho Nagib , Souza Neto Cláudio Pereira de
Published: November 2024

O texto apresenta a conceituação e função da Corte Constitucional, apresentando sua evolução de atuação nas culturas estadunidense, europeia e brasileira. Aponta a criação judicial (e não legislativa) da ideia de hierarquização do qual resultou o controle da constitucionalidade das leis nos EUA. Na Europa, discute o pensamento predominante quando da elaboração dos textos magnos e na instituição do controle de constitucionalidade. Em seguida, demonstra as características históricas absolutamente ímpares do processo constitucional do Brasil, embora derivadas dos sistemas europeu e norte americano.
Direitos fundamentais da educação: a efetividade dos programas públicos educacionais entre 2012 e 2022
Authors: Gerstenberger Junior Otto Guilherme , Val Eduardo Manuel
Published: November 2024

A investigação aborda a influência das empresas de educação superior no desenvolvimento socioeconômico do país durante o período de 2012 a 2022. A pesquisa é justificada pela necessidade de aprofundar o estudo dessa temática, alinhada à linha de pesquisa do Programa de Pós-Graduação Stricto Sensu da Universidade Federal Fluminense, com ênfase na sua abrangência e impacto social na realidade dos cidadãos. O estudo possui uma abordagem interdisciplinar, englobando as áreas das ciências econômicas, do direito, da administração de empresas, da educação e da sociologia, com especial atenção à consciência social e à sustentabilidade. O objetivo central fora fornecer uma visão macro e técnica de todos os elementos que influenciam o desenvolvimento do segmento de empresas de educação superior. Para alcançar esse propósito, o estudo realizou uma abrangente revisão de literatura específica, trazendo à tona dados e análises relevantes para o tema. A relação entre as empresas de educação superior e o direito é de extrema relevância no contexto estudado. O direito desempenha um papel fundamental na regulamentação e supervisão das atividades empresariais, garantindo a qualidade da educação, a proteção dos estudantes e a preservação dos interesses da como um todo. O direito também engloba a legislação sobre acesso à educação e políticas de inclusão, o que é particularmente relevante no contexto socioeconômico estudado. A criação de programas de financiamento estudantil, como o FIES (Fundo de Financiamento Estudantil) e o PROUNI (Programa Universidade para Todos), é uma iniciativa jurídica voltada para possibilitar o acesso ao ensino superior por parte de estudantes de baixa renda, contribuindo assim para a redução de desigualdades sociais.
O estado da arte do mercado de crédito de carbono: perspectiva de uma arquitetura regulatória no brasil
Authors: Marshall Carla Izolda Fiuza Costa , Flores Nilton Cesar
Published: November 2024

O artigo promove reflexão acerca dos parâmetros a serem utilizados para o mercado de crédito de carbono no Brasil, com vistas à sua inserção mundial. Nesse âmbito aborda o sistema normativo utilizado e a legislação, específica, em vigor à época da pesquisa, trazendo à baila análise do mercado de forma abrangente, no que tange aos dois tipos existentes. A metodologia adotada, em síntese, se deu por meio de pesquisa qualitativa, bibliográfica descritiva, documental e normativa, de forma a possibilitar o entendimento e a interferência na realidade investigada. A investigação dispôs como objetivos gerais de análise do mercado brasileiro e suas perspectivas, identificando se a regulação existente era suficiente para dar cumprimento às metas climáticas, e, quais, eventuais mudanças seriam necessárias para que o Brasil transforme seu potencial em riqueza e se insira no mercado internacional, a partir da análise do aparato normativo. Como resultado foi possível verificar que, ainda, não há regulação para o mercado de crédito de carbono no Brasil, o que se constitui num desafio a mais a ser ultrapassado, mas que há iniciativas que visam alterar o panorama atual. Nessa vertente, o mercado de crédito de carbono, cuja representatividade tem sido ampliada no contexto das nações e o Brasil precisa ser orientada de modo a ser preservada, mas, também, trazer recursos geradores de desenvolvimento econômico. Nesse contexto, imprescindível a elaboração de normas que regulem esse mercado e se insiram no ambiente internacional.
Indisponibilidade, interesse público e limites do consenso: novos balizamentos para uma sociedade moderna
Authors: Silva Junior Sidney Rosa da , Martins Plínio Lacerda
Published: November 2024

O presente trabalho busca situar um novo modelo de balizamentos da consensualidade no âmbito da sociedade moderna a partir de uma análise funcional-sistémica sobre os limites das observações jurídicas o gerenciamento de conflito realizado fora do modelo jurisdicional estatal. Nesse contexto, verifica-se as razões pelas quais os caminhos da autocomposição e da jurisdição estatal acabam sendo sempre insuficientes quando utilizados de forma isolada, demonstrando-se espaços a serem ocupados por cada um desses mecanismos de gerenciamento de conflitos. Em seguida se analisa a evolução de conceitos como indisponibilidade e interesse público para identificar os motivos pelos quais a indicação de seu conteúdo sempre restou bastante controvertida. Por fim, propõe-se um novo modelo para balizar a consensualidade face a uma visão atualizada das funções sociais da indisponibilidade, lastreado em um enfoque mais procedimental do que ontológico.
STUDY OF THE HISTORIOSOPHY OF THE WORKS OF TARAS SHEVCHENKO AT THE MILITARY HIGH SCHOOL
Authors:   Military Institute of Telecommunications and Informatization Heroes of Kruty, Kyiv, Ukraine, Logvinenko Nataliia
Published: November 2024

At various times in our history the Word of T. Shevchenko played an important role in the formation of the national consciousness of Ukrainians, in the struggle for the defense of their country, for truth, independence and a better future for the Ukrainian people. The poet's artistic heritage is a historical source from which we draw deep knowledge about our past. Kobzar's prophecies become our present. The poet's knowledge of the history of his native land fascinates, amazes, arouses respect and the desire to imitate him in studying the history of Ukraine. To organize integrated seminars "Poetic historiosophy of T. Shevchenko" in the course of the academic discipline "History of Ukraine and Ukrainian culture" in the military higher education institution is motivated by its content, since the significance of the creative activity of Kobzar is only mentioned in the context of the development of the culture of the Ukrainian people during the period of national revival in the first half of the 19th century. First of all, we find out the meaning of the concept of historiosophy and the peculiarities of T. Shevchenko's poetic historiosophy through the study of the scientific investigations of Ukrainian scientists and scholars. It is common knowledge that T. Shevchenko's deep interest in the history of Ukraine is noticeable in all periods of his work. The poet admires the history of the Cossacks, with whom he felt an organic unity. He sings of Cossack victories, victorious battles with the enemy on land and at sea, heroic figures of Cossack leaders, mourning the Zaporozhian past. The article highlights the generalized content of cadet studies on historiography, poetic historiosophy of T. Shevchenko as a way of in-depth study of his creative activity, the past and future of the Ukrainian people, popularization of his national idea. The word of T. Shevchenko still sprouts in our formidable present, awakens the people to fight for the defense of their native Ukraine.
THE ORIGIN AND DEVELOPMENT OF GERMAN TARAS SHEVCHENKO SCIENCE
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Marchuk Karyna
Published: November 2024

Taras Shevchenko is a writer who is known throughout the world. His works have been translated into many languages. However, the article focuses on the spread of Taras Hryhorovych's work in Germany, translations of his works into German. The article is devoted to the study of influence of Taras Hryhorovych on German culture, mainly literature. The main ways of spreading Kobzar's work were highlighted in the article. The first way was the spread through the work of German figures who lived in the territory of modern Ukraine. Interest in Taras Shevchenko also grew because of the Germans' love for the beauty of folk songs. Ukrainian figures also contributed to the spread of the artist's works. They made linear prose translations, provided materials, and helped in every way. The first mention of Shevchenko in Germany dates back to 1843. The magazine included a brief bibliographic information about Shevchenko's poem "Haidamaky". This first mention can be considered the beginning of German Shevchenko studies. Georg Obrist was the first translator of Taras Shevchenko's works. His goal was not to provide the best possible translation, but above all to interest professional translators and literary critics. Victor Umlauf von Frankvel, K.-E. Franzos and Yulia Virginia continued to work on translations and were significantly ahead of their predecessor. The article examines the achievements and shortcomings of Shevchenko's German translations. The general interest in the work of the Ukrainian writer was studied. The ways of spreading his creativity were not easy. Both German and Austrian writers and translators, as well as Ukrainian and Western European writers, joined the work. And thanks to their joint efforts and hard work, Ukrainian literature became known to the world.
Proteomic analysis of synergetic neuroprotective effect of adenosine, thiamine, niacin and cyanocobalamin in pathophysiology of diabetic polyneuropathy
Authors: Gromova O. A. , Torshin I. Yu. , Moiseenok A. G.
Published: November 2024

Background. Neurotransmitter adenosine and B-group vitamins have neuroprotective, remyelinizing and anti-neuroinflammatory properties. Despite the studies of these molecules for decades, the molecular mechanisms of their synergistic effect on neuroinflammation processes are unexplored and not systematized.

Objective: to establish the molecular mechanisms of synergism of adenosine, thiamine, niacin and cyanocobalamin in counteracting the pathology of diabetic polyneuropathy (DPN).

Material and methods. The molecular mechanisms of action of adenosine, thiamine (vitamin B1), niacin (vitamin PP) and cyanocobalamin (vitamin B12) in the pathophysiology of DPN were determined using functional analysis of genomic and proteomic databases.

Results. The analysis of 20,180 annotated proteins of the human proteome identified 504 vitamin-PP-dependent, 22 vitamin-B1-dependent, 24 vitamin-B12-dependent and 50 adenosine-dependent proteins. The proteins of the human proteome were detected, the activity or levels of which are important for reducing neuroinflammation, remyelination, neurogenesis, biosynthesis of neuronal adenosine triphosphate, myelin homeostasis, neuroplasticity, neutralization of homocysteine, regeneration of nerve fibers and maintaining the endothelium of the microvascular bed.

Conclusion. The discovered molecular mechanisms of synergism of the studied molecules are of fundamental importance for comprehension of the processes of neuroinflammation regulation and remyelination to prevent diabetic polyneuropathy and other neurodegenerative diseases.
Human genetic diversity and income inequality
Authors: Kilinc Mustafa , Kilinc Zeynel Abidin
Published: November 2024

This paper examines whether human genetic diversity is relevant to understand income inequality differences across countries. It extends the existing genetics-development studies in the literature to the relationship between genetics and inequality. The results obtained from 147 countries indicate that there is a statistically significant U-shaped relationship between genetic diversity and inequality. An important mediating factor in this relationship can be the level of trust in society. Genetic homogeneity can increase mutual support, aid, and cooperation in society. Hence, higher levels of genetic homogeneity can be associated with higher trust levels, which improves income equality. In addition, the relationship between genetics and the innovation capacity of societies can be another causal mechanism relating genetics to inequality.
Laboratory and instrumental parameters associated with the risk of death in the long-term follow-up period in patients after myocardial infarction
Authors: Mushikhina Natalia A. , Gorbatenko Elena A. , Teploukhova Alina I. , Yaroslavskaya Elena I. , Larionova Olga N.
Published: November 2024

BACKGROUND: In patients who successfully survived the 1st year after myocardial infarction, the risk of death remains elevated.
AIM: To determine laboratory and instrumental parameters of myocardial remodeling associated with a lethal outcome in the long-term follow-up period in patients 1 year after myocardial infarction.
MATERIAL AND METHODS: The study included 184 patients 12 months after myocardial infarction: the first group — living patients at the 5-year follow-up point (n=160), the second group — deceased patients at the 5-year follow-up point (n=24). A comparative analysis of inflammation and myocardial dysfunction biomarkers, as well as echocardiographic parameters reflecting the types of left ventricular remodeling, linear dimensions of the cavities and wall thickness of the heart, chamber volumes, and ventricular systolic function was retrospectively performed. After assessing the distribution of quantitative data, the Student's t-test or Mann–Whitney U-test and the χ2 criterion for categorical data were used. The model was built on the basis of logistic regression. The ROC curve, the Hosmer–Lemeshow test, and the bootstrap method were used to assess the model itself and its reliability.
RESULTS: Patients in the second group were older (p=0.007), and more often had myocardial infarction with ST-segment elevation during hospitalization (p 0.001). Twelve months after myocardial infarction, a multidirectional pattern of changes in the level of N-terminal brain natriuretic propeptide was revealed: a decrease was registered in the first group, while an increase was registered in the second group. In the dynamics of the second group, the index of end-diastolic volume (p=0.014) and the size of left ventricular asynergy were higher (p=0.043), and the ejection fraction was lower (p=0.015) than in the first group. The model for predicting 4-year mortality in patients who survived myocardial infarction during the 1st year included such parameters as the index of the left ventricular end-diastolic volume, the content of the N-terminal fragment of the natriuretic peptide and the presence of concentric hypertrophy of the left ventricle.
CONCLUSION: In patients who survived 1 year after myocardial infarction, the long-term risk of death is associated with a set of parameters reflecting left ventricular remodeling and the development of heart failure.
Simulation of Scalar Wave Propagation with High-Order Temporal and Spatial Accuracy by a New Multi-Axial Staggered-Grid Finite-Difference Scheme
Authors: Zhou Hongyu , Zhang Lele , Zhang Yabing
Published: November 2024

Staggered-grid finite-difference (SFD) stencils are extensively applied for scalar wavefield simulations and inversions in seismology because of their easy implementation and effectiveness of propagating the wave in heterogeneous media. The conventional SFD (CSFD) stencil adopts second-order temporal and high-order spatial finite-difference operators to approximate the partial derivatives inside the wave equation. The spatial SFD operator only adopts grid points along one orthogonally axial direction to approximate the spatial partial derivative along that direction. Therefore, increasing the number of grid points along the axis will not improve the temporal accuracy. To simultaneously enhance the temporal and spatial accuracy, we propose a new multi-axial SFD (MASFD) stencil, which consists of grid points along three directions for each partial derivative in space. The MASFD weightings (coefficients) are derived by preserving the dispersion relation of the scalar wave in the frequency–wavenumber domain. We prove that increasing the number of the grid points of the new stencil can simultaneously reach high-order accuracy in time and space. The performance of the new MASFD scheme is compared with the CSFD schemes by quantitative dispersion analyses, stability analyses, and numerical examples. Our comprehensive comparisons demonstrate that the MASFD scheme can be more accurate than the CSFD ones because of improved temporal accuracy. Under comparable accuracy, the MASFD scheme can be more efficient than the CSFD ones because the MASFD scheme can adopt larger time steps to perform stable wave extrapolation.
Front Cover
Authors: The Ohio Academy of Science
Published: November 2024

No abstract available.
Knowledge, attitudes, and practices of gynaecologists and paediatricians regarding newborn hearing screening in Odisha
Authors: Behera Dipika , Nandurkar Aparna
Published: November 2024

Background: Gynaecologists and paediatricians are crucial in detecting hearing loss at the first level of intervention. These healthcare workers are the ones who initially interact with infants and their parents. Therefore, they must understand the risk factors for newborn hearing loss and have a positive attitude toward early intervention.  There were few studies conducted to evaluate the Knowledge Attitude and Practices (KAP) of New Born Hearing Screening (NBHS) among paediatricians and other physicians in Western countries and few in the Indian context.  Thus, the current study aims to compare and examine the knowledge, attitudes, and practices of gynaecologists and paediatricians regarding newborn hearing screening in Odisha.
Methods: A survey questionnaire containing 45 close-ended and 5 open-ended questions was developed. This questionnaire was validated by paediatricians, gynaecologists, and audiologists and then applied among 300 professionals in Odisha.
Results: In all the sections it was found that paediatricians have greater knowledge than gynaecologists, however, both professionals have a positive attitude towards NBHS in Odisha. Mann-Whitney U test revealed significant differences in knowledge, attitudes, and practices among paediatricians and gynaecologists in Odisha.
Conclusions: From this survey, it can be concluded that most of the paediatricians know more about paediatric hearing loss in comparison to gynaecologists, while both of them have positive attitude in implementing NBHS in Odisha. An awareness should be created among both the professionals about NBHS, effect of hearing loss and to whom they can refer for NBHS, which will benefit the newborns and their parents.
A cross sectional study of prevalence and association of sensorineural hearing loss in patients with type 2 diabetes mellitus
Authors: M. K. Vybhavi , V. Srinivas , Muddaiah Dechu
Published: November 2024

Background: Diabetes mellitus (DM) is a chronic metabolic disorder associated with various long-term complications and among them hearing loss is one of the underestimated comorbidity. Objectives were to evaluate the prevalence of sensorineural hearing loss (SNHL) and to determine the association of age, gender, duration and control of DM with hearing loss.
Methods: A total of 130 patients aged 30-65 years with type 2 DM were included in this cross-sectional study. All patients were subjected to detailed history taking, ear, nose and throat examination followed by pure tone audiometry and measurement of glycosylated haemoglobin (HbA1c) levels.
Results: In this study, SNHL was seen in 70.76% of patients. Statistically significant association was found between the older age group, longer duration of DM and SNHL (p=0.00 and 0.002). Significant association was also seen between the severity of hearing loss and HbA1c levels with p=0.01.
Conclusions: Our study showed a high prevalence (70.76%) of SNHL among type 2 diabetic patients and evidently demonstrated significant association between age of the patients, duration of diabetes and SNHL as well as the association between glycemic control and the severity of hearing loss.
Large thyroglossal duct cyst with a long term evolution: a case report
Authors: Serrano-Trejo Isabel , Luna-Peteuil Zelik , Naranjo-Gonzalez Ana C. , Luna-Ortiz Kuauhyama
Published: November 2024

A 57-year-old male presented with a progressively enlarging mass in the anterior cervical region, persisting for 41 years without accompanying symptoms. Physical examination revealed a well-defined, mobile, soft mass measuring 16×15×15 cm, not fixed to deep tissues, and extending from the medial edge of the sternocleidomastoid muscle. Computed tomography scan showed a cystic lesion involving the hyoid bone, suggestive of a thyroglossal duct cyst. The patient underwent a Sistrunk procedure, with dissection from the base of the tongue to the sternal notch. He was discharged six hours after surgery without any complications and had a closed drainage system removed during a subsequent outpatient visit.
An incongruous occurrence: rare case of a huge sinonasal neurofibroma
Authors: Malhotra Vikas , Sethi Deepika , Mahajan Nidhi , Chatterjee Moudipa , Aggarwal Nitish
Published: November 2024

Neurofibromas (NF) are benign peripheral nerve sheath tumors that arise from schwann cells and intraneural fibroblasts. Solitary NF are extremely rare with only a few reported cases in the literature that involve the nasal cavity and paranasal sinuses. Due to its slow growth and the non-specific nature of the symptoms, its clinical presentation and diagnosis is often delayed. Here we present a case of a 65 year old female with left sinonasal neurofibroma which was surgically managed in our department successfully. It was 9.5 cm in greatest dimension and weighed 380 gm which is the largest amongst the available published reports that we could find.
A case report of nasal lobular capillary hemangioma and its management
Authors: K. Vybhavi M. , V. Srinivas
Published: November 2024

Nasal lobular capillary hemangioma is a benign vascular lesion marked by epistaxis and nasal obstruction. The nasal cavity is a relatively rare location as lobular capillary hemangiomas commonly occur in the oral cavity. They are termed as lobular capillary hemangioma based on the histopathological features of anastomosing capillary networks arranged in lobular architechture. We report a case of 40 year old female with history of left nasal obstruction and recurrent epistaxis since 2 months. Examination of nose revealed a protruding reddish coloured mass on the left side and CT scan of nose and paranasal sinuses showed the mass arising from the anterior part of nasal septum along with nasal spur. Patient underwent surgical excision of the mass along with spur removal under general anesthesia. Histopathology demonstrated vascular proliferative lesion consistent with hemangioma. The diagnosis of capillary hemangioma must always be taken into account while considering the differential diagnosis of bleeding mass in the nasal cavity.
The application of oral-motor learning principle in a patient with severe communication disabilities: a case study experience
Authors: Biswas Saheli , Adhikary Rumela , Hasan Abu , Chatterjee Indranil
Published: November 2024

Oral-motor learning principle uses by speech therapists to assist in the rehabilitation of motor impaired patients. To assess the application of oral-motor learning principle in severe communication disability. A case of age 7 years 7 month /male was diagnosed with severe intellectual disability secondary to spastic cerebral palsy with seizure disorder with visual impairment. 20 therapy sessions were provided, 45 minutes in each session. The goal of the therapy was to achieve functional communication skills up to single word level (5-10 words) in day-to-day clinical situations. Non speech oral motor exercises using oral motor sensory integration tool kits were used to improve vegetative functions and to reduce sialorrhea. Both the tactile kit and speech kit were used simultaneously. All the targets chosen had showed improvement of vegetative functions, reduced drooling and improved speech and language skills. It is concluded that oral motor sensory integration tool kits can be a standardized tool in treating oral motor deficits effectively.
Role of MMPs in connective tissue breakdown and periodontal disease: A Review
Authors: Sharma Ena , Goyal Radhika , Krishna Sreejith , Sangha Ruhee , Thind Simaran , Kaur Maninder
Published: November 2024

Matrix metalloproteinases (MMPs) are a group of zinc-dependent enzymes that play a critical role in the degradation of extracellular matrix components, including collagen, elastin, and proteoglycans, making them central to tissue remodeling processes. In the context of periodontal disease, MMPs are key mediators of connective tissue breakdown and alveolar bone destruction, driven by chronic inflammation. This review focuses on the role of MMPs in periodontal disease, highlighting their regulation, activation mechanisms, and the interplay with inflammatory cytokines such as interleukins and tumor necrosis factor-alpha (TNF-α). Furthermore, the review discusses the contribution of specific MMPs, including MMP-1, MMP-8, and MMP-9, in periodontal tissue degradation and explores potential therapeutic approaches to inhibit MMP activity to prevent periodontal disease progression. By understanding the molecular basis of MMP involvement in periodontal pathology, this review aims to provide insights into novel therapeutic strategies aimed at mitigating connective tissue breakdown in periodontal disease.
Evaluating the performance of ErbaQik sickle cell rapid test card with HPLC method
Authors: Lalla Poonam , Rughwani Vinky , Chugh Manoj
Published: November 2024

Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by the presence of abnormal hemoglobin, primarily hemoglobin S (HbS), resulting from a point mutation in the β-globin gene. ErbaQik Sickle Cell Rapid Test Card developed by Transasia Diagnostics Pvt Ltd will aid in rapid detection of Sickle cell disease particularly in resource & laboratory infrastructure limited settings.

To ensure the accuracy of ErbaQik Sickle Cell Rapid Test Card, a robust validation was conducted and compared with gold standard HPLC method to check the sensitivity, specificity, precision and clinical utility.

This study was conducted under the guidance of Consultant Paediatrician, from Dec 2023 to Feb 2024 at Nagpur center run by Thalassemia and Sickle cell Society of India in collaboration with Rughwani Child Care Centre to evaluate the performance of ErbaQik Sickle Cell Rapid Test Card with HPLC method which is the benchmark for comparison in this study. A total of 181 blood samples were analyzed for hemoglobin variants.

The evaluation of the ErbaQik Sickle Cell Rapid Test Card produced significant findings For Sickle-SS 32 samples were tested, all of which were correctly identified, yielding a sensitivity and specificity of 100%. Similarly 27 Trait-AS samples were all accurately detected, maintaining 100% sensitivity and specificity. These results indicate the test's high reliability and precision in identifying Sickle Cell Disease and Trait conditions. For Wild-Normal samples, the test was performed on 120 samples resulting in 100% sensitivity and specificity. In the case of Thalassemia samples, only 2 samples were tested, with 1 correctly identified, resulting in a sensitivity and specificity of 50%.

The ErbaQik Sickle Cell Rapid Test Card demonstrated high sensitivity and specificity for detecting Sickle Cell Disease (SS) and Trait (AS), aligning with gold-standard methods like HPLC.