bluuebunny/crossref_metadata_2025 huggingface dataset:
The Altotiberina Low-Angle Normal Fault (Italy) Can Fail in Moderate-Magnitude Earthquakes as a Result of Stress Transfer from Stable Creeping Fault Area
Authors: Vadacca Luigi
Published: April 2020

Geological and geophysical evidence suggests that the Altotiberina low-angle (dip angle of 15–20 ° ) normal fault is active in the Umbria–Marche sector of the Northern Apennine thrust belt (Italy). The fault plane is 70 km long and 40 km wide, larger and hence potentially more destructive than the faults that generated the last major earthquakes in Italy. However, the seismic potential associated with the Altotiberina fault is strongly debated. In fact, the mechanical behavior of this fault is complex, characterized by locked fault patches with a potentially seismic behavior surrounded by aseismic creeping areas. No historical moderate (5 ≤ Mw ≤ 5.9) nor strong (6 ≤ Mw ≤ 6.9)-magnitude earthquakes are unambiguously associated with the Altotiberina fault; however, microseismicity is scattered below 5 km within the fault zone. Here we provide mechanical evidence for the potential activation of the Altotiberina fault in moderate-magnitude earthquakes due to stress transfer from creeping fault areas to locked fault patches. The tectonic extension in the Umbria–Marche crustal sector of the Northern Apennines is simulated by a geomechanical numerical model that includes slip events along the Altotiberina and its main seismic antithetic fault, the Gubbio fault. The seismic cycles on the fault planes are simulated by assuming rate-and-state friction. The spatial variation of the frictional parameters is obtained by combining the interseismic coupling degree of the Altotiberina fault with friction laboratory measurements on samples from the Zuccale low- angle normal fault located in the Elba island (Italy), considered an older exhumed analogue of Altotiberina fault. This work contributes a better estimate of the seismic potential associated with the Altotiberina fault and, more generally, to low-angle normal faults with mixed-mode slip behavior.
Physical Parameters and Contrasts of Wooden Objects in Lacustrine Environment: Ground Penetrating Radar and Geoelectrics
Authors: Fediuk Annika , Wilken Dennis , Wunderlich Tina , Rabbel Wolfgang
Published: April 2020

We investigate how suitable ground penetrating radar (GPR) and geoelectrics are to prospect the remains of submerged wooden archaeological constructions in the water column. For this purpose, we determined the contrasts of electric resistivity and dielectric permittivity from measurements on present-day wood samples, serving as simplified approximations of water saturated and undegraded archaeological wood. As common substitutes of hard and soft construction wood, we investigated oak and spruce wood. The electric resistivity and dielectric permittivity were determined with increasing moisture content from small-scale electric and GPR measurements using a Wenner alpha array and a 2 GHz Palm antenna in a watering experiment. In a water-saturated state, resistivity values of <270 Ωm and relative dielectric permittivity values of >20 were observed. The anisotropy effects and deviations of the wood species were seen to be up to 30%. On the basis of this, the relative material contrasts of wood with respect to fresh water, sand, and clay were calculatedand compared to values found in the literature for seismic contrasts. Geoelectric, GPR, and seismic measurements show contrasts of 0.3 to 0.8, −0.4 to 0.2, and −0.24 to 0.35, depending on the surrounding material and structural orientation of the wood. The highest contrasts were found for wood in fresh water, followed by clayey and sandy subsoils. On the basis of the determined contrasts, analytical calculations were performed showing that an object of 0.5 m diameter can be detected at depths between 0.5 m and 1.5 m with geoelectrics (Schlumberger) and at depths between 0.5 m and 3 m with ground penetrating radar measurements (400 MHz).
Global High-Resolution Magnetic Field Inversion Using Spherical Harmonic Representation of Tesseroids as Individual Sources
Authors: Baykiev Eldar , Yixiati Dilixiati , Ebbing Jörg
Published: April 2020

In this study, we present a novel approach combining the advantages of tesseroids in representing geophysical structures though their voxel-like discretization features with a spherical harmonic representation of the magnetic field. Modelling of the Earth lithospheric magnetic field is challenging since part of the spectra is hidden by the core field and the forward modeled field of a lithospheric magnetization is always biased by the spectral range used. In our approach, a spherical harmonic representation of the magnetic field of spherical prisms (tesseroids) is used for high-resolution magnetic inversion of lithospheric field models. The use of filtered spherical harmonic models of the magnetic field of each tesseroid ensures that the resulting field matches the spectral range of the input data. For the inversion, we use the projected gradient method. The projected gradient method easily allows us to assign an initial guess (i.e., a-priori assumption) for the inversion and avoids negative values of susceptibilities. The latter is providing more plausible models since induced magnetization is assumed to be dominant over the continents and, for the oceans, a remanence model can be subtracted. We show an application of the technique to a synthetic dataset and a satellite-derived lithospheric field model where the model geometry is based on seismic information. We also demonstrate a proof-of-concept for high-resolution tile-wise inversion for the Bangui anomaly in Africa.
Low-Risk Planned Out-of-Hospital Births: Characteristics and Perinatal Outcomes in Different Italian Birth Settings
Authors: Campiotti Marta , Campi Rita , Zanetti Michele , Olivieri Paola , Faggianelli Alice , Bonati Maurizio
Published: April 2020

Background: The present observational study aimed to describe women and delivery characteristics and early birth outcomes according to planned out-of-hospital delivery and to compare this information with comparable planned in-hospital deliveries. Methods: 1099 healthy low-risk women who delivered out-of-hospital between 2014 to 2018, with a gestational age of 37–42 completed weeks of pregnancy, with single, vertex babies whose birth was expected to be vaginal and spontaneous were enrolled. Moreover, a case-control study was designed comparing characteristics of these births to a matched 1:5 sample. Results: living in a medium city (RR 1.81, 95% CI 1.19–2.74), being multiparous (RR 1.66, CI 1.09–2.51), having the first child at ≥35 years old (RR 1.84, CI 1.02–3.33), not working (RR 1.77, CI 1.06–2.96), not being omnivorous (RR 1.80, CI 1.08–3.00), and not smoking (RR 2.53, CI 1.06–6.07) were all related to an increased chance of delivering at home compared to in a freestanding midwifery unit. The significant factors in choosing to give birth out-of-hospital instead of in-hospital were living in a large or medium city (OR 2.20; 1.75–2.77; OR 2.41; 1.93–3.02) and having a secondary or higher level of education (OR > 2 for both parents). Within the first week of delivery, 6 of 1099 mothers and 19 of 1099 neonates were hospitalized. Conclusions: out-of-hospital births in women with low-risk pregnancies is a possible option that needs to be planned, monitored, regulated, and evaluated according to healthcare control systems in order to work, as in hospitals, for the safest and most effective care to a mother and her neonate(s).
Beyond Mistreatment at the Relationship Level: Abusive Supervision and Illegitimate Tasks
Authors: Stein Maie , Vincent-Höper Sylvie , Schümann Marlies , Gregersen Sabine
Published: April 2020

According to the concept of abusive supervision, abusive supervisors display hostility towards their employees by humiliating and ridiculing them, giving them the silent treatment, and breaking promises. In this study, we argue that abusive supervision may not be limited to mistreatment at the relationship level and that the abuse is likely to extend to employees’ work tasks. Drawing upon the notion that supervisors play a key role in assigning work tasks to employees, we propose that abusive supervisors may display disrespect and devaluation towards their employees through assigning illegitimate (i.e., unnecessary and unreasonable) tasks. Survey data were obtained from 268 healthcare and social services workers. The results showed that abusive supervision was strongly and positively related to illegitimate tasks. Moreover, we found that the relationship between abusive supervision and unreasonable tasks was stronger for nonsupervisory employees at the lowest hierarchical level than for supervisory employees at higher hierarchical levels. The findings indicate that abusive supervision may go beyond relatively overt forms of hostility at the relationship level. Task-level stressors may be an important additional source of stress for employees with abusive supervisors that should be considered to fully understand the devastating effects of abusive supervision on employee functioning and well-being.
Neurocognitive Inhibitory Control Ability Performance and Correlations with Biochemical Markers in Obese Women
Authors: Wen Huei-Jhen , Tsai Chia-Liang
Published: April 2020

Inhibitory control, the ability to suppress prepotent responses and resist irrelevant stimuli, is thought to play a critical role in the maintenance of obesity. However, electrophysiological performance related to different inhibitory control processes and their relationship with motor response inhibition and cognitive interference and potential biochemical mechanisms in middle-aged, obese women are as yet unclear. This work thus compared different neurocognitive Go/Nogo and Stroop task performance in healthy sedentary normal-weight and obese women, as well as their correlation with biochemical markers. Twenty-six healthy, sedentary obese women (obese group) and 26 age-matched (21–45 years old) normal-weight women (control group) were the participants, categorized by body mass index and percentage fat, as measured with dual-energy X-ray absorptiometry. They provided a fasting blood sample and performed two cognitive tasks (i.e., Go/Nogo and Stroop tasks) with concomitant electrophysiological recording. The N2 and P3 waveforms of event-related potential (ERP) were recorded. Although the between-group behavioral performance was comparable, the obese group relative to the control group showed significantly longer N2 latency and smaller P3 amplitude in the Stroop task and smaller N2 and P3 amplitudes in the Go/Nogo task. Significant inflammation response indices (e.g., CRP, leptin, adiponectin/leptin ratio) were observed in the obese group. The Nogo P3 amplitude was significantly correlated with the adiponectin/leptin ratio. These findings indicate that healthy obese women still exhibit deviant neurophysiological performance when performing Go/Nogo and Stroop tasks, where the adiponectin/leptin ratio could be one of the influencing factors for the deficit in neural processes of motor response inhibition.
Moral Obligation, Public Leadership, and Collective Action for Epidemic Prevention and Control: Evidence from the Corona Virus Disease 2019 (COVID-19) Emergency
Authors: Yang Liu , Ren Yang
Published: April 2020

To investigate the effect of villagers’ moral obligation and village cadres’ public leadership on villagers’ collective action for epidemic prevention and control, against the background of the corona virus disease 2019 (COVID-19) emergency in China, we constructed models based on the institutional analysis and development (IAD) framework and employed principal component analysis (PCA) and ordered probit regression, drawing on survey data from 533 villagers in Henan province adjacent to the COVID-19 origin province, Hubei, China. The results indicate that: (1) generally, both moral obligation and public leadership as well as their constituent indicators contributed positively to collective action for COVID-19 prevention and control; (2) moreover, moral obligation and public leadership can strengthen each other’s positive role in collective action for COVID-19 prevention and control. Based on the above findings, this paper suggests that villagers’ moral obligation can be perfected through internalizing epidemic prevention and control norms into the villagers’ moral norms by the way of villagers mastering the rural public health governance scheme. In addition, public leadership can be improved through professional training of village cadres and by motivating village elites to run for village cadres. With improved villagers’ moral obligation and village cadres’ public leadership, collective action for epidemic prevention and control could be more likely to be realized.
The Investigation of Gender Differences in Subjective Wellbeing in Children and Adolescents: The UP&DOWN Study
Authors: Esteban-Gonzalo Sara , Esteban-Gonzalo Laura , Cabanas-Sánchez Verónica , Miret Marta , Veiga Oscar L.
Published: April 2020

Objective: Based on a three-factor model of subjective wellbeing (evaluative, hedonic and eudemonic), the purpose of this study was to analyze gender differences in children and adolescents through three different subjective wellbeing indicators. Method: The sample comprised 1.407 children and adolescents from Cadiz and Madrid (Spain), in the framework of the UP&DOWN study. Life satisfaction was measured with the subjective happiness scale, positive and negative affect were measured with the positive and negative affect schedule, and purpose in life was assessed with the children’s hope scale. Results: Linear regression models indicate the existence of significant gender differences only in adolescents, with higher scores among girls in positive affect (p = 0.016) and negative affect (p < 0.001) but with lower scores in purpose in life (p = 0.024). Conclusions: These results highlight the role of gender as an important factor in explaining differences in subjective wellbeing. Additionally, results indicate that gender differences in subjective wellbeing are observed in adolescents, but not in children, suggesting that the gender gap in subjective wellbeing begins at the age of 12. Mental health practitioners should pay attention to these findings in order to implement screening methods and interventions focused on these needs.
Risk Attitude, Contract Arrangements and Enforcement in Food Safety Governance: A China’s Agri-Food Supply Chain Scenario
Authors: Hou Jing , Wu Linhai , Hou Bo
Published: April 2020

Frequent food safety problems in recent years have seriously affected China’s public health. The complexity, diversity, and technicality of food safety problems are intertwined, which constantly promotes the Chinese government and the food industry to explore effective food safety governance mechanisms. As the dominant form of vertical coordination in agri-food supply chain, contract farming is conducive to promoting farmers’ safe production behavior, improving food quality and safety, and ensuring public health. However, the low contract performance rate seriously restricts the effect of contract farming on reducing the risk of food safety in China. This paper empirically investigates the role of farmers’ risk attitude and contract arrangements in their enforcement. The data is derived from a household survey and economic field experiment of fruit farmers participating in contract farming in Anhui and Jiangsu provinces of China. We measure farmers’ risk attitude by using an economic field experiment, and examine how risk attitude and contract arrangements affect contract enforcement with a probit model. The results show that contract enforcement is significantly (1% level) influenced by farmers’ risk attitude. Farmers with greater risk aversion and loss aversion and farmers who are more accurate in evaluating probability information are more likely to fulfill the contract. Additionally, most contract arrangements have a significant effect on contract enforcement at the 5% level. Contract arrangements with floor pricing, bonus, and long duration are related to a higher rate of farmers’ contract performance. Furthermore, the factors influencing contract enforcement differ based on the levels of farmer’ risk attitude. The findings of the study may be conducive to formulating relevant agricultural policy to influence farmers’ decision-making and thus improving food safety and ensuring public health.
Association between Working Hours and Self-Rated Health
Authors: Jeon Jongha , Lee Wanhyung , Choi Won-Jun , Ham Seunghon , Kang Seong-Kyu
Published: April 2020

This study compared the association between working hours and self-rated health (SRH) according to sex, socioeconomic status, and working conditions. In all, 25,144 participants were selected from the Korea National Health and Nutrition Examination Survey (KNHANES), conducted from 2010 to 2018. The risks of poor SRH, according to working hours, were investigated using multiple logistic regression. Both short and long working hours were associated with poor SRH. Men working short hours and women working long hours were at risk of poor SRH. Workers with fewer than nine years of education were at risk of poor SRH when working short hours, whereas workers with more than nine years of education were at risk when working long hours. Similarly, simple laborers were at risk of poor SRH when working short hours, while managers and professional workers were at risk when working long hours. When working for short hours, paid employees were at risk of poor SRH. Workers with a non-fixed work schedule showed no risk of poor SRH when working long or short hours. In conclusion, workers working short hours with low education and workers working long hours with high education were at risk of poor SRH. Working conditions were significantly related to the association between SRH and working hours.
Reduced Cross-Shift Lung Function and Respiratory Symptoms among Integrated Textile Factory Workers in Ethiopia
Authors: Tefera Zele Yifokire , Kumie Abera , Deressa Wakgari , Moen Bente E. , Bråtveit Magne
Published: April 2020

Chronic respiratory symptoms and reduction in lung function has been described as a common health problem among textile workers in low- and middle-income countries. The objective of this study was to measure lung function and respiratory symptoms among workers from an integrated textile factory. A comparative cross-sectional study design with a cross-shift lung function measurement was performed in 306 cotton dust exposed workers from an integrated textile factory and 156 control workers from a water bottling factory. An integrated textile factory typically has four main production departments (spinning, weaving, finishing, and garment) that process raw cotton and manufacture clothes or fabrics. Respiratory symptoms were assessed by adopting the standard American Thoracic Society questionnaire. Descriptive statistics and logistic and linear regression analysis were used. The prevalence of respiratory symptoms was significantly higher among textile workers (54%) than in controls (28%). Chronic cough, chest tightness, and breathlessness were significantly higher among textile workers (23%, 33%, and 37%, respectively) than in the control group (5%, 17% and 6%, respectively). Breathlessness was the most prevalent chronic respiratory symptom with highest adjusted odds ratio 9.4 (95% CI 4.4–20.3). A significantly higher cross-shift lung function reduction was observed among textile workers (123 mL for FEV1 and 129 mL for FVC) compared with the control group (14 mL for FEV1 and 12 mL for FVC). Thus, workers’ respiratory health protection programs should be strengthened in textile factories.
Associations between Length of Stay in Long Term Care Facilities and End of Life Care. Analysis of the PACE Cross-Sectional Study
Authors: Collingridge Moore Danni , Payne Sheila , Keegan Thomas , Deliens Luc , Smets Tinne , Gambassi Giovanni , Kylänen Marika , Kijowska Violetta , Onwuteaka-Philipsen Bregje , Van den Block Lieve
Published: April 2020

Long term care facilities (LTCFs) are increasingly a place of care at end of life in Europe. Longer residence in an LTCF prior to death has been associated with higher indicators of end of life care; however, the relationship has not been fully explored. The purpose of this analysis is to explore associations between length of stay and end of life care. The analysis used data collected in the Palliative Care for Older People in care and nursing homes in Europe (PACE) study, a cross-sectional mortality follow-back survey of LTCF residents who died within a retrospective 3-month period, conducted in Belgium, England, Finland, Italy, the Netherlands and Poland. Primary outcomes were quality of care in the last month of life, comfort in the last week of life, contact with health services in the last month of life, presence of advance directives and consensus in care. Longer lengths of stay were associated with higher scores of quality of care in the last month of life and comfort in the last week of life. Longer stay residents were more likely to have advance directives in place and have a lasting power of attorney for personal welfare. Further research is needed to explore the underlying reasons for this trend, and how good quality end of life care can be provided to all LTCF residents.
Depressive Symptoms and Sleep Disturbance in Female Nurses with Atopic Dermatitis: The Korea Nurses’ Health Study
Authors: Kim Bohye , Jung Heeja , Kim Jiyoung , Lee Jisun , Kim Oksoo
Published: April 2020

Although the prevalence of atopic dermatitis is high in nurses, there is a lack of research on the relationship between atopic dermatitis and depressive symptoms and sleep disturbance among female nurses. This study aimed to determine the effects of atopic dermatitis on depressive symptoms and sleep disturbance in female nurses. We analyzed the data of the Korea Nurses’ Health Study, a large-scale prospective cohort study. A total of 20,613 female hospital nurses aged 20–45 years who participated in the Module 1 of Korea Nurses’ Health Study between July 2013 and November 2014 were included. The chi-square test, t-test, and multivariate ordinal logistic regression analysis were conducted for statistical analysis. The prevalence of atopic dermatitis among female nurses was 11.6%. The levels of depressive symptoms and sleep disturbance were higher in nurses with atopic dermatitis than those without atopic dermatitis. Nurses with atopic dermatitis were 1.16 times more likely to have depressive symptoms and 1.35 times more likely to have sleep disturbance than those without atopic dermatitis after adjusting for confounding variables. The results of this study suggest that additional support should be considered for nurses with atopic dermatitis to improve the occupational environment for managing and preventing the exacerbation of symptoms.
Effects of a Workplace-Based Virtual-Run Intervention Among University Employees
Authors: Wattanapisit Apichai , Amaek Waluka , Promma Watcharawat , Srirug Phatcharawadee , Cheangsan Uchane , Khwanchum Satit , Chadakorn Wattana , Eardmak Kanittha , Chadakorn Narumon
Published: April 2020

Virtual runs (real running or walking activities using online recording platforms) have been popular in the digital age and could have the potential to promote physical activity (PA) in workplaces. We investigated the effects of a virtual-run intervention (VRI) on PA and body compositions among university employees. A three-phase intervention was conducted over 6 months: 0 (pre-intervention), 1 (during intervention), and 2 (post-intervention). Exercise stages of change were assessed in phases 0 and 2. Body compositions (body weight, body mass index, fat mass, percentage of fat mass, fat-free mass, and percentage of fat-free mass) were assessed in phases 0, 1, and 2. Running and walking times were recorded through a mobile application. Forty-seven participants completed the VRI. The number of participants at the maintenance stage increased from 34.04% in phase 0 (n = 16) to 63.83% in phase 2 (n = 30). None of the changes in body compositions were significant (p > 0.05). The median running and walking time among participants at the maintenance stage was 151.85 (interquartile range, 109.15) min/week. Future research should focus on approaches to improve the efficacy of VRIs and their effects on health outcomes.
A Model for Improving Diet Quality within Child Nutrition Programs: The U.S. Army’s Child and Youth Services Healthy Menu Initiative
Authors: Hanson Jennifer , Joyce Jillian , Laursen Denise , Paez Paola
Published: April 2020

The U.S. Army’s Child, Youth, and School Services (CYS), which has the capacity to serve more than 70,000 meals/snacks per day, is a geographically dispersed system with facilities worldwide. This case report is a description and evaluation of the implementation of a major food program initiative within the CYS system. In collaboration with Kansas State University, the Healthy Menu Initiative was established to standardize the system’s menus, reflect the guidance contained within the 2015–2020 Dietary Guidelines for Americans, and take into account the Child and Adult Care Food Program regulations that went into effect on 1 October 2017. Food storage space, food service equipment, product availability, food safety considerations, and staff shortages have all proven to be challenges in the development and implementation of the menus. Participant acceptance has been an issue in some instances, and special diet requirements add to the workload of the staff. To overcome these challenges, input was solicited from CYS management, care providers, food service staff, and participant families, as well as participants themselves. Taste testing and classroom cooking activities have been developed to increase acceptance, and over 500 CYS food program staff have attended in-depth training sessions to support the initiative. Overall, the initiative has been well received, and there has been an improvement in the diet quality of the foods served within the program. This improvement is noteworthy, as optimal growth and development during childhood and adolescence are reliant on sound nutrition.
Workplace Violence and Its Effects on Burnout and Secondary Traumatic Stress among Mental Healthcare Nurses in Japan
Authors: Kobayashi Yudai , Oe Misari , Ishida Tetsuya , Matsuoka Michiko , Chiba Hiromi , Uchimura Naohisa
Published: April 2020

Workplace violence (WPV) in healthcare settings has drawn attention for over 20 years, yet few studies have investigated the association between WPV and psychological consequences. Here, we used a cross-sectional design to investigate (1) the 12-month prevalence of workplace violence (WPV), (2) the characteristics of WPV, and (3) the relationship between WPV and burnout/secondary traumatic stress among 599 mental healthcare nurses (including assistant nurses) from eight hospitals. Over 40% of the respondents had experienced WPV within the past 12 months. A multivariate logistic regression analysis indicated that occupation and burnout were each significantly related to WPV. Secondary traumatic stress was not related to WPV. Our results suggest that WPV may be a long-lasting and/or cumulative stressor rather than a brief, extreme horror experience and may reflect specific characteristics of psychological effects in psychiatric wards. A longitudinal study measuring the severity and frequency of WPV, work- and non-work-related stressors, risk factors, and protective factors is needed, as is the development of a program that helps reduce the psychological burden of mental healthcare nurses due to WPV.
Shallow Landslide Susceptibility Mapping: A Comparison between Logistic Model Tree, Logistic Regression, Naïve Bayes Tree, Artificial Neural Network, and Support Vector Machine Algorithms
Authors: Nhu Viet-Ha , Shirzadi Ataollah , Shahabi Himan , Singh Sushant K. , Al-Ansari Nadhir , Clague John J. , Jaafari Abolfazl , Chen Wei , Miraki Shaghayegh , Dou Jie , Luu Chinh , Górski Krzysztof , Thai Pham Binh , Nguyen Huu Duy , Ahmad Baharin Bin
Published: April 2020

Shallow landslides damage buildings and other infrastructure, disrupt agriculture practices, and can cause social upheaval and loss of life. As a result, many scientists study the phenomenon, and some of them have focused on producing landslide susceptibility maps that can be used by land-use managers to reduce injury and damage. This paper contributes to this effort by comparing the power and effectiveness of five machine learning, benchmark algorithms—Logistic Model Tree, Logistic Regression, Naïve Bayes Tree, Artificial Neural Network, and Support Vector Machine—in creating a reliable shallow landslide susceptibility map for Bijar City in Kurdistan province, Iran. Twenty conditioning factors were applied to 111 shallow landslides and tested using the One-R attribute evaluation (ORAE) technique for modeling and validation processes. The performance of the models was assessed by statistical-based indexes including sensitivity, specificity, accuracy, mean absolute error (MAE), root mean square error (RMSE), and area under the receiver operatic characteristic curve (AUC). Results indicate that all the five machine learning models performed well for shallow landslide susceptibility assessment, but the Logistic Model Tree model (AUC = 0.932) had the highest goodness-of-fit and prediction accuracy, followed by the Logistic Regression (AUC = 0.932), Naïve Bayes Tree (AUC = 0.864), ANN (AUC = 0.860), and Support Vector Machine (AUC = 0.834) models. Therefore, we recommend the use of the Logistic Model Tree model in shallow landslide mapping programs in semi-arid regions to help decision makers, planners, land-use managers, and government agencies mitigate the hazard and risk.
Long-Term Employment Outcomes among Female Cancer Survivors
Authors: Ekenga Christine C. , Kwon Eunsun , Kim BoRin , Park Sojung
Published: April 2020

Advances in early detection and treatment have led to a growing population of female cancer survivors, many of whom are of working age. We examined the relationship between cancer and long-term (>5 years) employment outcomes in a nationally representative sample of working-age women in the United States. Data from nine waves of the Health and Retirement Study were used to examine employment status and weekly hours worked among cancer survivors (n = 483) and women without cancer (n = 6605). We used random slope regression models to estimate the impact of cancer and occupation type on employment outcomes. There was no difference in employment status between cancer survivors and women without cancer at baseline; however, during follow-up, cancer survivors were more likely to be employed than women without cancer (odds ratio (OR) = 1.33, 95% confidence interval (CI): 1.11–1.58). Among 6–10-year survivors, professional workers were less likely (OR = 0.40, 95% CI: 0.21–0.74) to be employed than manual workers. Among >10-year survivors, professional workers averaged fewer weekly hours worked (−2.4 h, 95% CI: −4.4–−0.47) than manual workers. The impact of cancer on long-term employment outcomes may differ by occupation type. Identifying the occupation-specific mechanisms associated with the return to work will be critical to developing targeted strategies to promote employment in the growing female cancer survivor population.
Evaluating Spatial Accessibility to General Hospitals with Navigation and Social Media Location Data: A Case Study in Nanjing
Authors: Qian Tianlu , Chen Jie , Li Ang , Wang Jiechen , Shen Dingtao
Published: April 2020

Spatial accessibility to general hospitals is an important indicator of the convenience and ability of residents to obtain medical services. Therefore, developing a model for measuring accessibility to general hospitals by multiple transportation modes is necessary. In this study, considering that the increase in travel time will reduce the attractiveness of general hospitals, we used the Two-Step Floating Catchment Area with the Gaussian attenuation function, in which the supply was presented by capacity of hospitals (i.e., number of beds), and the demand was presented by population in each grid derived with social media data mapping real-time locations of active users. The Gaussian Two-Step Floating Catchment Area (Ga2SFCA) simulates the attenuation tendency of the general hospital service capabilities over transit time. To obtain a highly precise understanding of accessibility to hospitals, transit time on Baidu Maps’ navigation service was used as the impedance condition, and the study area was divided into 1 square kilometer grids as the basic unit of research. Taking Nanjing city as a case study, it is found that the accessibility distribution shape changes from a multi-centered circular pattern to a multi-peak distribution, as the time threshold increases. By comparing the accessibility among 11 districts varying from main urban area to suburbs, the accessibility to general hospitals in Nanjing is significantly regionally unbalanced in both travel modes. By calculating and mapping the Modal Accessibility Gap (MAG) of the two travel modes, different modes of transportation resulted in different general hospital accessibility distributions. Generally, private car is superior in access to general hospitals to public transit in most areas. In the central area, public traffic may not contribute to the access to medical services as much as we thought, rather it plays a role in areas far from hospitals along metro lines and bus routes.
The Influence of Continuous Improvement of Public Car-Sharing Platforms on Passenger Loyalty: A Mediation and Moderation Analysis
Authors: Ma Fei , Guo Dan , Yuen Kum Fai , Sun Qipeng , Ren Fuxia , Xu Xiaobo , Zhao Chengyong
Published: April 2020

Public car-sharing is a growing business model that contributes to sustainable transportation and urban development. The continuous improvement of public car-sharing platform to garner passenger loyalty is vital for a car-sharing platform’s success. This study applied perceived value theory, trust theory, and transaction cost theory to construct a structural equation model in order to explain passenger loyalty. Data from 755 surveys were collected using stratified sampling in mainland China. The estimated results of the theoretical model show that the relationship between continuous improvement and passenger loyalty is mediated by passenger perceived value, passenger trust, and transaction costs. Consequently, a multi-group analysis is conducted to analyze the moderation effects of passenger’s license and car-sharing experience on the theoretical model. The results show that some of the path coefficients are significantly different between these sub-groups. This indicates that platforms should provide differentiate services for passengers based on the purpose of using car-sharing and usage experience. This study provides new theoretical insights into understanding passenger loyalty with respect to public car-sharing and provides policy recommendations for the sustainable development of public car-sharing.
COVID-19 Pandemic and the Crisis of Health Systems: The Experience of the Apulia Cancer Network and of the Comprehensive Cancer Center Istituto Tumori “Giovanni Paolo II” of Bari
Authors: Silvestris Nicola , Moschetta Antonio , Paradiso Angelo , Delvino Antonio
Published: April 2020

On 11 March 2020, the World Health Organization declared a new disease caused by a novel virus characterized by rapid human-to-human transmission and named severe acute respiratory syndrome coronoavirus-2 (SARS-CoV-2) a pandemic. In terms of this ongoing international scenario, we report the situation in Apulia, a region of southern Italy that, as of April 2, has not yet been overwhelmed by this health emergency. In particular, we consider the care models that have been adopted, especially those that manage the requests of cancer patients.
Acute and Chronic Dopaminergic Depletion Differently Affect Motor Thalamic Function
Authors: Di Giovanni Giuseppe , Grandi Laura Clara , Fedele Ernesto , Orban Gergely , Salvadè Agnese , Song Wei , Cuboni Eleonora , Stefani Alessandro , Kaelin-Lang Alain , Galati Salvatore
Published: April 2020

The motor thalamus (MTh) plays a crucial role in the basal ganglia (BG)-cortical loop in motor information codification. Despite this, there is limited evidence of MTh functionality in normal and Parkinsonian conditions. To shed light on the functional properties of the MTh, we examined the effects of acute and chronic dopamine (DA) depletion on the neuronal firing of MTh neurons, cortical/MTh interplay and MTh extracellular concentrations of glutamate (GLU) and gamma-aminobutyric acid (GABA) in two states of DA depletion: acute depletion induced by the tetrodotoxin (TTX) and chronic denervation obtained by 6-hydroxydopamine (6-OHDA), both infused into the medial forebrain bundle (MFB) in anesthetized rats. The acute TTX DA depletion caused a clear-cut reduction in MTh neuronal activity without changes in burst content, whereas the chronic 6-OHDA depletion did not modify the firing rate but increased the burst firing. The phase correlation analysis underscored that the 6-OHDA chronic DA depletion affected the MTh-cortical activity coupling compared to the acute TTX-induced DA depletion state. The TTX acute DA depletion caused a clear-cut increase of the MTh GABA concentration and no change of GLU levels. On the other hand, the 6-OHDA-induced chronic DA depletion led to a significant reduction of local GABA and an increase of GLU levels in the MTh. These data show that MTh is affected by DA depletion and support the hypothesis that a rebalancing of MTh in the chronic condition counterbalances the profound alteration arising after acute DA depletion state.
HIV-1 and Amyloid Beta Remodel Proteome of Brain Endothelial Extracellular Vesicles
Authors: András Ibolya E. , Sewell Brice B. , Toborek Michal
Published: April 2020

Amyloid beta (Aβ) depositions are more abundant in HIV-infected brains. The blood–brain barrier, with its backbone created by endothelial cells, is assumed to be a core player in Aβ homeostasis and may contribute to Aβ accumulation in the brain. Exposure to HIV increases shedding of extracellular vesicles (EVs) from human brain endothelial cells and alters EV-Aβ levels. EVs carrying various cargo molecules, including a complex set of proteins, can profoundly affect the biology of surrounding neurovascular unit cells. In the current study, we sought to examine how exposure to HIV, alone or together with Aβ, affects the surface and total proteomic landscape of brain endothelial EVs. By using this unbiased approach, we gained an unprecedented, high-resolution insight into these changes. Our data suggest that HIV and Aβ profoundly remodel the proteome of brain endothelial EVs, altering the pathway networks and functional interactions among proteins. These events may contribute to the EV-mediated amyloid pathology in the HIV-infected brain and may be relevant to HIV-1-associated neurocognitive disorders.
Neuroprotective Properties of Resveratrol and Its Derivatives—Influence on Potential Mechanisms Leading to the Development of Alzheimer’s Disease
Authors: Wiciński Michał , Domanowska Anna , Wódkiewicz Eryk , Malinowski Bartosz
Published: April 2020

The lack of effective Alzheimer’s disease treatment is becoming a challenge for researchers and prompts numerous attempts to search for and develop better therapeutic solutions. Compounds that affect several routes of the neurodegeneration cascade leading to the development of disease are of particular interest. An example of such substances is resveratrol and its synthetic and natural derivatives, which have gained popularity in recent years and show promise as a possible new therapeutic option in the approach to Alzheimer’s disease treatment. In this article, the state of the art evidence on the role of resveratrol (RSV) in neuroprotection is presented; research results are summarized and the importance of resveratrol and its derivatives in the treatment of Alzheimer’s disease are underlined. It also focuses on various modifications of the resveratrol molecule that should be taken into account in the design of future research on drugs against Alzheimer’s disease.
Chondrogenic Potential of Pellet Culture Compared to High-Density Culture on a Bacterial Cellulose Hydrogel
Authors: Grigull Nele Pascale , Redeker Julia Isabelle , Schmitt Bärbel , Saller Maximilian Michael , Schönitzer Veronika , Mayer-Wagner Susanne
Published: April 2020

Cell-based approaches of cartilage lesions use different culture systems to obtain optimal cell quality. Pellet cultures with high cellular density (HD) are the gold standard to keep chondrocytes in a differentiated stage. Bacterial cellulose (BC) hydrogel is discussed to prevent cellular aging and dedifferentiation. The hypothesis of this study was that HD culture on BC hydrogel (HD hydrogel) might reach the chondrogenic potential of pellet culture (pellet). Human articular osteoarthritic (OA) and non-osteoarthritic (non-OA) chondrocytes were cultured for seven days within pellets and compared to HD hydrogel and HD polystyrene. Gene expression analysis and histological assessment were performed. We observed no significant change of COL2A1 expression by the culture system (pellet, HD hydrogel and HD polystyrene) but a significant change of COL2A1/COL1A1-ratio, with the highest ratio in pellets. Chondrocytes on HD hydrogel showed an elevated expression of MMP13 and on polystyrene an increased expression of COL1A1 and MMP13. The patterns of gene expression changes observed in OA and non-OA chondrocytes in reaction to the different culture systems were similar in those two cell groups. Pellet cultures moreover formed a histomorphologically superior neocartilage. Concluding, human chondrocytes kept the potential to express COL2A1 in all HD culture systems. However, pellets excelled in a higher COL2A1/COL1A1-ratio, a higher extracellular matrix deposit and in not developing degeneration and dedifferentiation markers. This underlines the superiority of pellet culture in maintaining the chondrogenic potential of human chondrocytes in vitro.
Security and Privacy of QR Code Applications: A Comprehensive Study, General Guidelines and Solutions
Authors: Wahsheh Heider A. M. , Luccio Flaminia L.
Published: April 2020

The widespread use of smartphones is boosting the market take-up of dedicated applications and among them, barcode scanning applications. Several barcodes scanners are available but show security and privacy weaknesses. In this paper, we provide a comprehensive security and privacy analysis of 100 barcode scanner applications. According to our analysis, there are some apps that provide security services including checking URLs and adopting cryptographic solutions, and other apps that guarantee user privacy by supporting least privilege permission lists. However, there are also apps that deceive the users by providing security and privacy protections that are weaker than what is claimed. We analyzed 100 barcode scanner applications and we categorized them based on the real security features they provide, or on their popularity. From the analysis, we extracted a set of recommendations that developers should follow in order to build usable, secure and privacy-friendly barcode scanning applications. Based on them, we also implemented BarSec Droid, a proof of concept Android application for barcode scanning. We then conducted a user experience test on our app and we compared it with DroidLa, the most popular/secure QR code reader app. The results show that our app has nice features, such as ease of use, provides security trust, is effective and efficient.
Competing Vegetation Structure Indices for Estimating Spatial Constrains in Carabid Abundance Patterns in Chinese Grasslands Reveal Complex Scale and Habitat Patterns
Authors: Tsafack Noelline , Fattorini Simone , Benavides Frias Camila , Xie Yingzhong , Wang Xinpu , Rebaudo François
Published: April 2020

Carabid communities are influenced by landscape features. Chinese steppes are subject to increasing desertification processes that are changing land-cover characteristics with negative impacts on insect communities. Despite those warnings, how land-cover characteristics influence carabid communities in steppe ecosystems remains unknown. The aim of this study is to investigate how landscape characteristics drive carabid abundance in different steppes (desert, typical, and meadow steppes) at different spatial scales. Carabid abundances were estimated using pitfall traps. Various landscape indices were derived from Landsat 8 Operational Land Imager (OLI) images. Indices expressing moisture and productivity were, in general, those with the highest correlations. Different indices capture landscape aspects that influence carabid abundance at different scales, in which the patchiness of desert vegetation plays a major role. Carabid abundance correlations with landscape characteristics rely on the type of grassland, on the vegetation index, and on the scale considered. Proper scales and indices are steppe type-specific, highlighting the need of considering various scales and indices to explain species abundances from remotely sensed data.
Prognostic Value of Neutrophil-To-Lymphocyte Ratio and Platelet-To-Lymphocyte Ratio for Renal Outcomes in Patients with Rapidly Progressive Glomerulonephritis
Authors: Mae Yukari , Takata Tomoaki , Ida Ayami , Ogawa Masaya , Taniguchi Sosuke , Yamamoto Marie , Iyama Takuji , Fukuda Satoko , Isomoto Hajime
Published: April 2020

Background: Rapidly progressive glomerulonephritis (RPGN) is a syndrome characterized by a rapid decline in renal function that often causes end-stage renal disease. Although it is important to predict renal outcome in RPGN before initiating immunosuppressive therapies, no simple prognostic indicator has been reported. The aim of this study was to investigate the associations of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) to renal outcomes in patients with RPGN. Methods: Forty-four patients with a clinical diagnosis of RPGN who underwent renal biopsy were enrolled. The relationships between NLR and PLR and renal outcome after 1 year were investigated. Results: NLR and PLR were significantly higher in patients with preserved renal function in comparison to patients who required maintenance hemodialysis (p < 0.05 and p < 0.01, respectively). An NLR of 4.0 and a PLR of 137.7 were the cutoff values for renal outcome (area under the curve, 0.782 and 0.819; sensitivity, 78.4% and 89.2%; specificity, 71.4% and 71.4%, respectively). Furthermore, an NLR of 5.0 could predict recovery from renal injury in patients requiring hemodialysis (area under the curve, 0.929; sensitivity, 83.3%; specificity, 85.7%). Conclusion: NLR and PLR could be candidates for predicting renal outcomes in patients with RPGN.