bluuebunny/crossref_metadata_2025 huggingface dataset:
Perinatal Outcome of Babies Delivered to Eclamptic Mothers: A Prospective Study from a Nigerian Tertiary Hospital
Authors:   Departments of Paediatrics, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Nigeria, George Innocent O. , Jeremiah Israel ,   Department of Obstetrics and Gynaecology, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Nigeria
Published: October 2023

Background: Eclampsia is a leading cause of maternal and perinatal mortality in Nigeria. Preventive and interventional measures have been shown to reduce maternal mortality and morbidity with no significant beneficial effect on neonatal outcomes. The aim of this study is to assess the perinatal outcome of eclampsia at the University of Port-Harcourt Teaching Hospital (UPTH). Materials and methods: This prospective, cross-sectional study was conducted on 88 consecutive patients presenting with antepartum eclampsia at the UPTH between 1st January 2007 and 31st December 2008. A protocol was developed and used to collect information about socio-demographic characteristics, mode of delivery, perinatal complications and outcome. Data collected was entered into a spread sheet using SPSS 15.0 for Windows® statistical software which was also used for analysis. Chi square was used to test relationship between variables. P value<0.05 was considered statistically significant. Results: There were a total of 5488 deliveries at the University of Port-Harcourt Teaching Hospital from January 2007 to December 2008. Of these, 5,310 were live births while 404 were perinatal deaths giving perinatal mortality rate of 73.6 per 1000 live births. Eighty eight (1.6%) of the mothers were eclamptic. Eight (9.1%) were booked, 80 (90.1%) were unbooked. The mean gestational age at delivery was 35.1 ± 4.2 weeks. The main mode of delivery was by emergency caesarian section in 49 (55.7%) of the patients. Others were spontaneous vertex delivery (34.1%), assisted vaginal breech delivery (6.8%) and instrumental vaginal delivery (3.4%). Fifty four babies (61.4%) were admitted into the Special Care Baby Unit. Indications for admission include prematurity (n=23), low birth weight (n=10), severe birth asphyxia (n=12), neonatal jaundice (n=4) and neonatal sepsis (n=5). There were 37 perinatal deaths giving a perinatal mortality rate of 411 per 1000 live births. Of the mortalities, 19 were intrauterine foetal deaths, while 18 were early neonatal deaths. Causes of death include severe birth asphyxia (n=6), respiratory distress syndrome (n=4), prematurity (n=4), neonatal jaundice (n=1) and sepsis (n=3). Conclusion: Eclampsia is a major contributor of perinatal mortality and morbidity in Nigeria. Detection and appropriate management of preeclampsia is critical to reduce the risk of eclampsia.
A 28-Days Sub-Acute Toxicity Study in Swiss Albino Mice to Evaluate Toxicity Profile of Neurotol Plus (Mannitol and Glycerol Combination)
Authors:   Intellectual Scientific Divison, R & D Centre, Venus Remedies limited, 51-52 Industrial Area, Panckula, Haryana, India, Sehgal Rajesh , Tamta Anupama , Chaudhary Manu
Published: October 2023

Osmotic agents are still the most common treatment options available for controlling intracranial pressure (ICP). Combining Mannitol and Glycerol provides a better alternative and is currently available as best therapy used for increased ICP. The aim of this work was to study the effects of repeated dosing (28 days) of Mannitol 20% and Glycerol 10% combined formulation, Neurotol plus on safety profile. A twenty eight days sub-acute toxicity study was conducted at three different dose levels of 5ml/kg, 10 ml/kg and 20 ml/kg. Mice were randomly divided into four groups of six animals each. Physical parameters, biochemical parameters related to liver toxicity & nephrotoxicity and hematological parameters were studied as end point of evaluation. We also carried out histopathlogical studies to assess any organ specific toxicity. The present study demonstrated that there were either no or very minimal changes (at high dose) were observed on various physical, biochemical and hematological parameters between Neurotol plus and control group. In conclusion the data of present study suggest that the combination of Mannitol and Glycerol is not associated with any serious adverse effects and is safe therapeutic choice for ICP reduction.
An evaluation of the unconsolidated hydrogeologic units in the south-central Flathead Valley, Montana
Authors:   Montana Bureau of Mines and Geology, Bobst A. , Rose J. , Berglund J.
Published: October 2023

An evaluation of the work that has been done at the BFF site. Stratigraphy (including downhole geophysics) from a 1600 ft well drilled in 2021 into the tertiary sediments underlying the deep aquifer. Water-quality results from wells in the tertiary, deep aquifer, confining layer, and shallow aquifer. Aquifer tests and hydrograph analysis of the shallow aquifer, confining layer, deep aquifer, and tertiary sediments. Evaluation of using TEM and MT surficial geophysical techniques.
Analisis Evaluasi Kelayakan Finansial pada Saga Fitness di Kecamatan Tenggarong Seberang Kabupaten Kutai Kartanegara
Authors: Herawati Herawati
Published: October 2023

Operasi dan ekspansi yang efisien membutuhkan penilaian iklim bisnis yang konstan. Kesehatan fiskal perusahaan adalah ukuran penting dari keberhasilannya. Faktor keuangan biasanya hanya salah satu dari sekian banyak faktor yang diperhitungkan dalam evaluasi. Studi ini mengkaji situasi keuangan Saga Fitness di Tenggarong Seberang, Kabupaten Kutai Katanigara, dari tahun 2020-2025. Studi ini dilakukan untuk mengevaluasi kelangsungan hidup jangka panjang Saga Fitness antara tahun 2020 dan 2025. Dengan mewawancarai pemilik perusahaan, Endah Tri Wahyuni, pendekatan kuantitatif deskriptif dapat dilakukan. Titik impas, periode pengembalian modal, dan nilai sekarang bersih adalah komponen dari analisis kelayakan finansial. Analisis titik impas menunjukkan bahwa setelah hanya lima tahun beroperasi, Saga Fitness menghasilkan keuntungan dari penjualan produknya. Profitabilitas ditunjukkan dengan rasio kotor 90% dan margin kontribusi Rp 1.194.443.600. Dengan total pendapatan sebesar Rp 2.438.884.096 sejauh ini di tahun 2018, Saga Fitness memiliki lebih dari cukup uang untuk menutupi semua biaya operasionalnya. Profitabilitas awal Saga Fitness sangat menggembirakan untuk kesuksesan dan pertumbuhan perusahaan di masa depan. Perhitungan ROI menunjukkan bahwa Saga Fitness membutuhkan waktu 3,0 tahun, atau 3,6 bulan, untuk mengembalikan investasi awal mereka. Temuan ini memvalidasi kelayakan finansial Saga Fitness karena nilai pengembaliannya sesuai dengan umur ekonomis komersial bersih dari investasi tersebut. NPV dari keuntungan selama lima tahun terakhir adalah sebesar Rp 1.138.996.843. Temuan ini menunjukkan kepraktisan dan penerimaan pendekatan ini; oleh karena itu, pendekatan ini dapat digunakan untuk sisa investigasi.
Heterosis for yield and yield attributing traits in tomato (Solanum lycopersicum L.)
Authors: Kumar Kiran , Sharma Dhananjay , Singh Jitendra , Chandel Nisha
Published: October 2023

Six diverse lines of tomato were crossed with four testers inline x tester (L×T) cross design to investigate the extent ofheterosis for yield and its contributing traits in tomato. Thepresent investigation was carried out under AICRP onVegetable Crops at Horticultural Research cum InstructionalFarm, Department of Vegetable Science, IGKV, Raipur (C.G.)during rabi 2017-18. A high degree of heterosis wasobserved for most of the characters under investigation.High per se performance with remarkable heterosis wereexpressed by PR x 14/TLCV-3, KA x 15/TLCV-2, H-86 x 14/TLCV-3, KA x 14/TLCV-3 and H-24 x 14/TLCV-1 for higherfruit yield, however, a high degree of heterosis for othertraits in desired direction was also observed
Response to selection through introgression breeding in onion (Allium cepa L.)
Authors: Gupta Amar Jeet , Mahajan V , Singh SR , Sheemar G , Singh Major
Published: October 2023

Development of suitable varieties of onion with high yieldas well as good shelf life through crossing between longand short-day onion was carried out at the Research Farmof ICAR-Directorate of Onion and Garlic Research,Rajgurunagar, Pune in collaboration with ICAR-CITH,Srinagar. A total of 135 crosses were made between available15 exotic onion varieties and 9 short day lines at ICARCITH,Srinagar. The crosses were evaluated in their F2generation and further selection were continued up to F5generation. The experiment was laid out in randomized blockdesign with three replications during rabi seasons toinvestigate the genetic variability and response to selectionamong all the crosses. Top seven progenies which wereselected on the basis of high yield in F2 generation whichwere also good performers in F3 generation with high yieldand other desirable traits. The selected crosses were foundfree from doubles and bolters in F3 generation. This indicatesthe selection done from F2 to F3 generation is effective fordouble and bolter bulbs which certainly helps to increasethe marketable bulb yield. High degree of variation wasobserved for all the traits studied and the difference betweenphenotypic and genotypic coefficient of variation was foundto be narrow for most of the traits. More than 30% marketableyield enhancement was observed in four progenies viz.,Couger × DOGR-595, Reforma × DOGR-595, Mercedes ×Bhima Super and Collina × DOGR-597 in comparison withbest check Bhima Shakti (41.17 t/ha) in F3 generationwhereas, more than 50 t/ha marketable yield was recorded infour progenies viz., Basic × RGO-53, Couger × DOGR-595,Mercedes × Bhima Super and Reforma × DOGR-595 in F3generation.
Performance of parthenocarpic lines of brinjal (Solanum melongena L.) in net house and open field during the rainy season
Authors: Sarangal Anupama , Sidhu Mohinder Kaur , Dhatt Ajmer Singh
Published: October 2023

Brinjal carries facultative parthenocarpy that is affected byseasonal variation and the environment of cultivation.Twenty-four parthenocarpic genotypes involving threeparthenocarpic hybrid checks and one non-parthenocarpicvarietal check (Punjab Neelam) were included to assess theirperformance under net house and open-field conditionsduring the rainy season. The genotypes, environments, andtheir interactions affected the performance of all the traitsunder investigation. Among the genotypes, PC-104-13-3,PC-104-13-1, PC-104-12-2, PC-104-3-1, PC-133-1, PC-136-4,PC-115-1, and non-parthenocarpic check Punjab Neelam hadbeen the best for vegetative growth, while 93213-PC-2-1and 93213-PC-2-3 for earliness and yield-related traits. Ingeneral, all the vegetative, flowering, fruiting, and yieldrelatedtraits flourished better under net house conditionsas compared to open field conditions. Interaction effectsbetween environment and genotype indicated that 93213-PC-2-1 and 93213-PC-2-3 were earlier for days to first harvest(35.0 and 38.0 days), at the top for the number of flowers percluster (10.67 and 11.33, respectively), the number of fruitsper cluster (6.67 and 7.00, respectively) and the maximumnumber of marketable fruits per plant (25.51 and 28.03,respectively), when grown under net house conditions. Themaximum and statistically at par average fruit weight wasobserved in PC-104-13-1 (298.33 g) and parthenocarpichybrid check Nikki (291.67 g) in net house conditions. Theparthenocarpic genotypes PC-123-1 (2.89 kg), PC-2016-6-2(2.87 kg), PC-1-12-2 (2.78 kg), PC-104-13-1 (2.64 kg), PC-17-1(2.61 kg), parthenocarpic hybrid checks Shelly (2.74 kg) andNikki (2.73 kg), and Amaron check (2.55 kg) displayed at parmarketable fruit yield per plant under net house conditions.In all, the marketable yield and its related traits during therainy season were affected by the environment of cultivation,where the parthenocarpic genotypes performed better innet house conditions in brinjal.
Inheritance of white seed coat colour in sponge gourd [Luffa cylindrica (L.) Roem.]
Authors: Munshi AD , Singh Jogendra , Sureja AK , Behera TK , Choudhary H , Dey SS
Published: October 2023

Sponge gourd (Luffa cylindrica Roem.), also known asdishrag gourd, dishcloth gourd, loofah gourd, andsmooth loofah is a very popular vegetable grown underlow input condition in the tropical and subtropicalregions. The other vernacular names of sponge gourdin India are kali tori, ghia tori, toria, nemia, chiori,dhundul, thuppa heera kayi, ghosali, gilka, bhol or tarada.It is an important component of cropping system duringpre-kharif and kharif seasons in North Indian plain regionas it has the ability to set fruits at extremely hightemperature prevailing during May-June and is cultivatedboth on commercial scale and in kitchen gardens. Thesponge gourd is grown in many parts of the world butis more common crop in China and other Asian countries.
Evidence confirms the occurrence of stenospermocarpic seedless fruit development in pointed gourd (Trichosanthes dioica Roxb.)
Authors: Karmakar Pradip , Bhardwaj DR , Singh BK , Chaubey T , Singh Vikas , Singh PM , Behera TK
Published: October 2023

Pointed gourd (Trichosanthes dioica) is a perennial andvegetatively propagated cucurbitaceous vegetable grownfor its tender fruits, and the occurrence of harder seedsreduces consumers’ preference. The present study wasundertaken to understand the mechanism of seedless fruitdevelopment in pointed gourd. The period of rapid fruitgrowth and development in pointed gourd took placegenerally 3-7 days after pollination due to faster cell divisionand cell enlargement. Significantly higher fruit growthrecorded in seeded clone as compare to seedless clones(49.1% for fruit length, 16.7% for fruit diameter and 55.2%for fruit weight) at harvestable fruit maturity but at the sametime no significant differences found at initial stage of fruitdevelopment. The occurrence of various mechanisms ofseedless fruit development such as vegetativeparthenocarpy, stimulative parthenocarpy andstenospermocarpy have been studied in details throughdifferent pollination treatments in both seeded and seedlessclones. In seedless clone, the growth/development of seedwas normal for first 3-4 days after pollination and becomeabnormal (aborted and degenerated embryo, shriveled anddisintegrated cotyledons, traces of aborted seeds yellowishwhitein colour and zero per cent seed germination) indicatethe existence of fertilization and subsequent abortion offertilized embryo which confirms the occurrence ofstenospermocarpic seedlessness and absence of stimulativeparthenocarpy in pointed gourd.
Influence of planting time and mulching on yield and quality of direct sown muskmelon (Cucumis melo L.) under low tunnel
Authors: KR Anusha , Singh Kulbir , Sardana Virender , Sharma Sat Pal , Singh Rajinder
Published: October 2023

An investigation was undertaken to study the impact ofdate of sowing and mulching under low tunnel conditionson the growth, yield and quality of direct sown muskmelonduring 2019-20 and 2020-21 at Vegetable Research Farm andBiochemical Laboratory of Punjab Agricultural University,Ludhiana. Treatments were comprised of four dates ofsowing (15th November, 15th December, 15th January underlow tunnels and 15th February in open conditions) and twomulch treatments (black polythene mulch and non-mulch).Muskmelon hybrid, MH-27 planted on 15th November gavehigher number of fruits (4.0), highest total yield (216.6 q/ha),ascorbic acid (22 mg/100g) and dry matter (8.6 %). 15th Januaryplanting gave highest vine length (186.8 cm), maximum fruitdiameter (17.6 cm), maximum fruit weight (830.3 g) and TSS(12 °Brix). Mulched plants exhibited better growth, yieldand quality when compared with non-mulch plants. It isconcluded that muskmelon sown under low tunnel on 15thNovember with black polythene mulch offers higher yieldand maximum net returns and B: C ratio.
Generation mean analysis unveils genetic effects controlling major yield traits in okra [Abelmoschus esculentus (L.) Moench].
Authors: Yadav RK , ND Vinay , Behera TK , A Talukdar1 A Talukdar , Lata Suma , Das Anjan
Published: October 2023

The present study on generation means analysis was carriedout to uncover genetics of yield traits in okra. To determinethe nature and magnitude of gene action six generations(P1, P2, F1, F2, BC1 and BC2) of cross Pusa Sawani x PusaBhindi- 5 was assessed. The results revealed that bothadditive and dominance gene effects were significant ingenetic control of yield traits. However, the magnitude ofdominance gene effects was significant and higher for seedgermination per cent, days to first flower, node to first flower,number of fruiting nodes, plant height and fruit yield perplant. Therefore, heterosis breeding would be effective toimprove these traits. Additive genetic effect was significantfor days to 50 per cent flower, inter-nodal length, number ofprimary branches, fruit length, fruit diameter and fruit weight.Result of scaling tests confirmed the role of non-allelicinteraction in genetic control of all the yield traits analysed.The opposite sign of dominance (h) and dominance xdominance interaction (l) for many yield traits suggestedrole of duplicate type of epistasis, while few charactersexhibited complementary type of epistasis. For improvingtraits with higher fixable (additive and additive x additive)component of genetic variation, pedigree method of breedingwould be useful. For traits showing significant values ofboth additive and non-additive gene effects, improvementcan be done by either recurrent selection or bi-parentalmating system in segregating generations followed byselection.
Effect of drip irrigation scheduling on yield attributes and water productivity of bitter gourd-cabbage-cowpea cropping sequences
Authors: Bahadur Anant , Singh Shekhar , Singh DK , Chaurasia SNS
Published: October 2023

Enhanced water and nutrient use efficiency, crop yield withsuperior quality can be achieved by adopting drip irrigationand fertigation system in vegetables. Drip irrigation studywas carried out in bitter gourd, cabbage and cowpea cropsequences respectively during Kharif, Rabi and Zaidseasons. Treatment comprised of four drip irrigationscheduling i.e., drip irrigation at 100% ET or 75% ET withirrigation scheduling daily or alternate day. Conventionalfurrow irrigation was also kept as control. In bitter gourd,maximum fruit yield of 143.00 q/ha was recorded with dripirrigation scheduling daily at 100% ET, whereas maximumWUE (4.657 q/ha/cm) was recorded in drip irrigationschedule at alternate day with 75% ET. Similarly, in cabbage,drip irrigation scheduling daily or alternate day with 100%ET registered 36.18% and 34.78% higher head yield,respectively over surface irrigation. In summer season, mostof the growth and yield parameters in cowpea weresignificantly enhanced with drip irrigation at 100% ET.However, most of the yield parameters recorded under 100%ET daily or 100% ET with alternate day were noticed at par.These two treatments have registered 22.8% and 18.4%higher yield over conventional irrigation. In cowpea, WUEunder drip irrigation system were 1.54 to 1.69 times higherthan the surface irrigation. It was concluded from presentstudy that drip irrigation at 100% ET daily or alternate daysignificantly enhanced the productivity of bitter gourd,cabbage and cowpea, however maximum WUE were reportedwith 75% ET.
Punjab Kheera Hybrid-11 (PKH-11): A new hybrid of parthenocarpic gynoecious cucumber (Cucumis sativus L.) for poly-net house cultivation
Authors: Dhall RK
Published: October 2023

Cucumber (Cucumis sativus L.) is one of the mostimportant cucurbitaceous salad vegetable crops grownextensively in tropical and sub-tropical parts of India.Its primary centre of origin is India (Zeven and Deweb1982) and secondary centre of diversification is China(De Candolle 1882). It is grown throughout the worldand is the fourth most important vegetable crop aftertomato, cabbage and onion (Tatlioglu 1993).
Identification of potential chilli (Capsicum annuum L.) accession as a rootstock for managing bacterial wilt disease in bell pepper
Authors: PK Nischay , Ponnam Naresh , Acharya Gobinda Chandra , Barik Satyaprakash , V Sandeep , Kumari Meenu , P Srinivas , Sahoo Gouri Shankar
Published: October 2023

Bacterial wilt caused due to Ralstoniapseudosolanacearum is pervasive across the majorpepper growing parts of world and impede production.It is reported that 30-100% yield losses in crops wasdue to bacterial wilt (James et al. 2003). Ralstoniapseudosolanacearum is highly heterogeneous bacterialpathogen cause wilting of important crops (Smith et al.1995). These pathogen propagules remain viable andactive in soil for several years making the control almostimpossible through any means of cultural managementlike crop rotation, involvement of biological agents aswell as chemical treatments especially in the regionswhere repeated and protected cultivation is undertaken(Thakur et al. 2014).
A new strain of Papaya ring spot virus infecting ivy gourd (Coccinia grandis L.) in India
Authors: K Nagendran , SK Manoranjitham , G Karthikeyan
Published: October 2023

Ivy gourd (Coccinia grandis L.) plants showing virus likesymptoms such as mosaic mottling and thickening of leaflamina were collected from Tindivanam, Tamil Nadu. ThroughReverse transcription polymerase chain reaction, infectionof potyvirus was confirmed with the yield of desiredamplicon (~1.0 kb) using universal primer pair. Sequenceanalysis of amplified product showed the infection of Papayaring spot virus (PRSV). Further association of PRSV wasconfirmed with PRSV specific primer pair (GK PRSV F/R).The nucleotide sequence analysis showed identity of coatprotein region shared only 84% with PRSV isolate fromThailand in BLAST analysis. In phylogenetic analysis, PRSVinfecting ivy gourd formed a separate cluster from otherPRSV isolates. This confirms the association of distinct strainof PRSV on Ivy gourd in India.
Biocontrol effects of endophytic and rhizospheric bacteria against the root pathogen Fusarium oxysporum of hot pepper (Capsicum annum L.)
Authors: Fentahun Gezahign , Kibret Mulugeta , Stotaw Baye , Asrat Atrsaw
Published: October 2023

Plant disease needs to be controlled to keep the quality ofproducts and the abundance of food produced by farmersall over the world. Hot pepper production in Ethiopia hasbeen reduced from time to time. This is mainly due to theoutbreak of different diseases especially fusarium wilt inthe hot pepper growing areas. The objective of this studywas to isolate and characterize Plant Growth PromotingBacteria from the hot pepper rhizosphere and internal tissueswith potential biocontrol activity against Fusariumoxysporum. Thirty healthy and vigorous hot pepper plantswith intact roots and soil from the rhizospheric region werecollected randomly from hot pepper growing areas of YimaliKebele. A total of 23 endophytic and rhizospheric bacteriawere isolated from the hot pepper root and rhizosphericsoil. The combined endophytic and rhizospheric bacteriashowed a significant effect on the growth of F. oxysporumthan single isolates (P d”0.05). The bacteria isolated fromMarkofana hot pepper varieties of black clay soil showed abetter antagonistic effect on F. oxysporum than bacteriaisolated from local hot pepper varieties of reddish sandysoil. A significant percentage of inhibition between combinedendophytic and rhizospheric bacteria [endophytic (GE) +rhizospheric (GR) isolates] compared to GE+GE and GR+GR(P =0.002) was obtained. Antagonistic bacterial isolates wereable to produce different hydrolytic enzymes such aschitinase, protease, and cellulase. Bacillus species showedbetter antagonistic performance and decreased radial growthof F. oxysporum than Pseudomonas species.
Induction of chlamydospores to enhance the shelf-life in Trichoderma asperellum using phosphorus deficient medium
Authors: Maurya Sudarshan , Singh DP , Naik SK , Pandey KK
Published: October 2023

immense group of microbes habituating especially fungaland bacterial microorganisms and these soil microbeshave ability to transform complex compounds intosimpler that enter again the ecosystem as well as theyalso mobilize, biotransformation and bioaccumulationprocesses of nutrients, micronutrient and heavy metalsin the soil (Gadd 1993). Morphological behaviour andactivity of the microbes highly influenced by theenvironmental factors and nutrient stress such asdrought, heat, salinity, cold, can have a devastating impacton microbial activities as well as on plant growth andcrop yield (Suzuki et al. 2014). Multiple tip-formationsnear the hyphal apex in filamentous fungi especially inAspergillus nidulans and Neurospora crassa due toenvironmental and nutritional stress and this phenomenonhappened due to disturbance of the process of tipextension and such aberration might be potential benefitsin increasing the number of exploratory branchesemanating from a mycelium to tackle risk of theenvironmental factors (Markham 1992).
Dynamics of anthocyanin and chlorophyll content in red fruited okra var. Kashi Lalima
Authors: Karmakar Pradip , Sagar Vidya , Singh PM
Published: October 2023

An experiment was conducted with the objectives to study the dynamics of anthocyanin and chlorophyll content at various stages of fruit growth and development in the red fruited okra variety Kashi Lalima and also to evaluate nutritional quality at harvestable maturity stage. Anthocyanin and total chlorophyll content of the fruits of Kashi Lalima studied with the help of spectrophotometer at various stage of fruit growth i.e., starting from zero days after anthesis (0 DAA) to 35 DAA. It has been observed that chlorophyll is the only pigment detected in the mature ovary at the time of anthesis, while no anthocyanin is detected at 0 DAA. Traces of anthocyanin detected only at 2 DAA and the content in gradually increased up to 8 DAA (3.90 mg/100g FW) i.e., during harvestable stage for fresh vegetable. At this point of time fruits are scarlet red in colour. Fading of coloration start at 10 DAA and significant discoloration observed at 35 DAA (1.99 mg/100g FW). On the other hand significant amount of chlorophyll was also reported from 0 DAA to 35 DAA.This study provides the insight of the red coloration of the fruit of Kashi Lalima, pattern of anthocyanin pigmentation and identification of the appropriate stage of harvesting for better nutritional quality.
A review of the status of the Herring Gull Larus argentatus in Spain
Authors: Álvarez-Laó C
Published: October 2023

The Herring Gull Larus argentatus is considered a regular but scarce visitor to Spain, but its detailed status is uncertain. Here I present a compilation of published (primarily annual bird reports) and unpublished information (internet forums, direct communications by local ornithologists, ringing recoveries) to clarify the distribution and numbers of Herring Gulls in Spain, and their origins. More detailed information on age composition and phenology is presented for Asturias (NW Spain), perhaps the region where the species is most studied. According to ring recoveries (n = 43), the majority of Herring Gulls visiting Spain belong to the subspecies L. a. argenteus (mainly from the British Isles), with only 7% coming from breeding areas of the Nordic subspecies L. a. argentatus. Most observations occur in autumn and winter, being scarcer in spring and summer, and numbers vary between years. Two-thirds of birds recorded were in their first two years of life, with adults comprising only a quarter of the total. Ringing recoveries suggest Herring Gulls were more common in Spain 30+ years ago than at present. Data from winter censuses in Asturias between 2002 and 2007 gave a mean proportion of 1.06% Herring Gulls amongst the Yellow-legged Gull L. michahellis contingent. It is estimated that between 250 and 400 Herring Gulls are present in Asturias in mid January, and between 500 and 700 in the whole of Spain at the time of the winter censuses. There are two possible but unconfirmed attempts of breeding.
Heart Disease Prediction under Machine Learning and Association Rules under Neutrosophic Environment
Authors: El-Douh Ahmed A. , Lu SongFeng , Abdelhafeez Ahmed , Ali Ahmed M. , Aziz Alber S.
Published: October 2023

Early identification and precise prediction of heart disease have important implications for preventative measures and better patient outcomes since cardiovascular disease is a leading cause of death globally. By analyzing massive amounts of data and seeing patterns that might aid in risk stratification and individualized treatment planning, machine learning algorithms have emerged as valuable tools for heart disease prediction. Predictive modeling is considered for many forms of heart illness, such as coronary artery disease, myocardial infarction, heart failure, arrhythmias, and valvar heart disease. Resource allocation, preventative care planning, workflow optimization, patient involvement, quality improvement, risk-based contracting, and research progress are all discussed as management implications of heart disease prediction. The effective application of machine learning-based cardiac disease prediction models requires collaboration between healthcare organizations, providers, and data scientists. This paper used three tools such as the neutrosophic analytical hierarchy process (AHP) as a feature selection, association rules, and machine learning models to predict heart disease. The neutrosophic AHP method is used to compute the weights of features and select the highest features. The association rules are used to give rules between values in all datasets. Then, we used the neutrosophic AHP as feature selection to select the best feature to input in machine learning models. We used nine machine learning models to predict heart disease. We obtained the random forest (RF) and decision tree (DT) have the highest accuracy with 100%, followed by Bagging, k-nearest neighbors (KNN), and gradient boosting have 99%, 98%, and 97%, then AdaBoosting has 89%, then logistic regression and Naïve Bayes have 84%, then the least accuracy is support vector machine (SVM) has 68%.
Incarner les récits de la Boîte aux lettres : mettre en oeuvre des archives personnelles pour se raconter
Authors: Tessier Eugénie
Published: October 2023

Le trio musical acadien Les Hay Babies lançait en 2020 leur troisième album, Boîte aux lettres, un projet né de la découverte d’une collection de lettres personnelles datées de 1965 et signées par une mystérieuse Jackie. À travers la manipulation de ces objets de mémoire, le projet des Hay Babies mène à une exposition singulière et intime du récit de cette Acadienne originaire de Moncton et déménagée à Montréal pour y faire sa vie. Dans ce texte, je m’interroge sur la dimension performative de l’archive en tant qu’objet sous le prisme du concept de reenactment, une réflexion étayée par les interventions médiatiques des Hay Babies ainsi que des critiques et journalistes dans la presse musicale. En prenant principalement pour cas la chanson Les vieilles filles, j’observe ensuite comment les représentations historiques suscitées par les pratiques de mises en oeuvre déployées par le groupe donnent lieu à un processus réflexif et intersubjectif par lequel ces dernières en viennent à se raconter.
DÉ-GÉNÉRATION-ELLES – trauma et transmission intergénérationnelle : un projet photographique artistique à partir des archives des rescapées du génocide arménien
Authors: Choulakian Lucia
Published: October 2023

L’expérience des femmes arméniennes lors du génocide arménien de 1915 reste largement méconnue et écartée des discours courants. L’artiste Lucia Choulakian, née en Acadie et descendante de la quatrième génération des rescapées du génocide arménien, cherche à comprendre et à exprimer ce trauma qui lui a été transmis. C’est alors par un projet photographique, de nature autobiographique, Dé-génération-elles, qu’elle aborde ce trauma transgénérationnel. Le projet se base sur des photographies de femmes tatouées arméniennes, rescapées du génocide arménien, trouvées dans les archives. Cet article présente le processus de création de l’oeuvre Dé-génération-elles afin de démontrer comment les dispositifs théoriques et pratiques se sont entrecroisés et souligner l’apport des théories et des archives dans l’élaboration de son travail artistique sur la transmission du trauma. Suite à une mise en contexte historique et méthodologique, son processus créateur est présenté de façon chronologique.
Vers une reconstitution de la mobilité des Acadiennes à l’époque de l’industrialisation : l’émigration familiale et l’exode rural vus à travers l’analyse longitudinale
Authors: Deschambault Lauraly , Haché-Chiasson Noémie , Kennedy Gregory
Published: October 2023

Cette analyse de type longitudinale expérimentale vise à retrouver les Acadiennes de la paroisse civile de Dundas, au sud-est du Nouveau-Brunswick dans la région de Kent, et à identifier leurs déplacements tout au long de leur vie afin de mieux comprendre les migrations effectuées par les femmes à l’époque de l’industrialisation. Une reconstitution des parcours de vie de quatre échantillons d’Acadiennes entre 1871 et 1921 est effectuée à partir d’une variété de sources historiques incluant des actes de mariage, des registres de baptême ainsi que les recensements canadiens et américains. Les résultats témoignent de l’ampleur de l’émigration aux États-Unis, mais également de la mobilité locale, régionale et interprovinciale. L’importance du réseau familial était primordiale. D’ailleurs, une proportion considérable des femmes sont restées sédentaires toute leur vie et il y a également une mobilité de retour à la campagne. Cette analyse préliminaire témoigne du potentiel d’utiliser les archives pour analyser la mobilité des femmes avant le mariage, dans le contexte d’une émigration familiale, et aussi après le décès de leurs conjoints. En fin de compte, une analyse approfondie des expériences des Acadiennes apporte beaucoup de nuances à notre compréhension des tendances migratoires et de la notion d’exode rural en Acadie du Nouveau-Brunswick à cette époque.
Le transhumanisme au service de l’idéologie du travail : un nouvel instrument de l’exploitation capitaliste ?
Authors: Fauvel Guillaume
Published: October 2023

Avec la division cognitive du travail qui accompagne l’évolution néolibérale des sociétés, l’efficacité ne résulte plus de la parcellarisation des processus de production en des tâches simples, répétitives et rigoureusement délimitées, mais de la capacité des forces de travail à investir dans leurs facultés d’apprentissage, d’innovation et d’adaptation afin de les maximiser en suivant les besoins perpétuels de l’appareil de production et sa dynamique de changement continu. En cela le transhumanisme représenterait le meilleur instrument dont dispose aujourd’hui le néolibéralisme pour atteindre l’objectif ultime d’une dépolitisation totale des individus et de la société au profit d’une économisation intégrale des individus et de la société. En véhiculant l’idéal d’une « augmentation technologique de l’humain », le transhumanisme enrôlerait l’individu à investir son humanité en la comprenant uniquement en termes de capital humain pour mieux la faire entrer intégralement sur le marché économique comme source d’adaptation à ce nouveau milieu dans lequel la compétition généralisée doit être perçue comme « naturelle ». Cela apparenterait le transhumanisme à une forme particulière de propagande au service de « l’idéologie du travail » de Jacques Ellul, développée par le néolibéralisme.
Architects of the Information Society
Authors: Garfinkel Simson L.
Published: October 2023

This book, published in celebration of the 35th anniversary of MIT's LCS, chronicles its history, achievements, and continued importance to computer science.

The Massachusetts Institute of Technology's Laboratory for Computer Science (LCS) has been responsible for some of the most significant technological achievements of the past few decades. Much of the hardware and software driving the information revolution has been, and continues to be, created at LCS. Anyone who sends and receives email, communicates with colleagues through a LAN, surfs the Web, or makes decisions using a spreadsheet is benefiting from the creativity of LCS members.LCS is an interdepartmental laboratory that brings together faculty, researchers, and students in a broad program of study, research, and experimentation. Their principal goal is to pursue innovations in information technology that will improve people's lives. LCS members have been instrumental in the development of ARPAnet, the Internet, the Web, Ethernet, time-shared computers, UNIX, RSA encryption, the X Windows system, NuBus, and many other technologies.This book, published in celebration of LCS's thirty-fifth anniversary, chronicles its history, achievements, and continued importance to computer science. The essays are complemented by historical photographs.
An anciently diverged family of RNA binding proteins maintain correct splicing of ultra-long exons through cryptic splice site repression
Authors: Siachisumo Chileleko , Luzzi Sara , Aldalaqan Saad , Hysenaj Gerald , Dalgliesh Caroline , Cheung Kathleen , Gazzara Matthew R , Yonchev Ivaylo D , James Katherine , Chadegani Mahsa Kheirollahi , Ehrmann Ingrid , Smith Graham R , Cockell Simon J , Munkley Jennifer , Wilson Stuart A , Barash Yoseph , Elliott David J
Published: October 2023

We previously showed that the germ cell specific nuclear protein RBMXL2 represses cryptic splicing patterns during meiosis and is required for male fertility. It has remained unknown whether RBMXL2 evolved its role in splicing repression to deal with the transcriptionally permissive environment of meiosis or might fulfil a function required in all cells. RBMXL2 evolved from the X-linked RBMX gene, which is silenced during meiosis due to sex chromosome inactivation. Here we find that like RBMXL2, RBMX primarily operates as a splicing repressor in somatic cells, and specifically regulates a distinct class of exons that exceed the median human exon size. RBMX protein-RNA interactions are enriched within ultra-long exons, particularly within genes involved in genome stability, and RBMX represses the selection of cryptic splice sites that would compromise gene function. These similarities in overall function suggested that RBMXL2 during meiosis might replace the otherwise ubiquitous RBMX protein. To test this prediction we carried out inducible expression of RBMXL2 and the more distantly related RBMY protein in somatic cells, finding each could rescue aberrant patterns of RNA processing in response to RBMX depletion. The C-terminal disordered domain of RBMXL2 is sufficient to rescue proper splicing control after RBMX depletion. Our data indicate that RBMXL2 replaces RBMX during meiosis, and these proteins have maintained parallel roles that must have been conserved over at least 200 million years of mammalian evolution. We propose RBMX family proteins are important for the splicing inclusion of ultra-long exons because these are particularly susceptible to disruption by cryptic splice site selection.
Exploring Hydroponics and the Associated Technologies for Use in Medium-and Small-scale Operations: A Review
Authors: Verma Rajesh Chandra , Chaithanya G.  , Sachan Prashun , Thilagam P. , Bahadur Raj , Kumar Neeraj , Singh Bal Veer , Mahesha K. N.
Published: October 2023

Hydroponics, the science of soilless agriculture, has emerged as a pivotal paradigm in modern cultivation practices, addressing myriad challenges of traditional farming and offering avenues for high-efficiency, sustainable food production. This review delves into the anticipated future directions of hydroponics, capturing its interdisciplinary evolution. Central to this trajectory is the integration of Artificial Intelligence (AI) and machine learning, aiming to augment precision in every facet of hydroponic cultivation, from nutrient balance to disease prediction. Complementing technological advancements is the burgeoning realm of genomics, poised to craft crop varieties intrinsically optimized for hydroponic conditions, promising both enhanced yields and improved nutritional profiles. Sustainability remains an unwavering focus, with innovative methodologies underscoring recycling and resource optimization, ensuring minimal waste and maximal output. The synergistic amalgamation of hydroponics with other agricultural models, notably aquaponics, paints a picture of integrated, multi-tiered ecosystems that not only boost productivity but also bolster ecological resilience. Such integrations herald a future where farming transcends singular methodologies, evolving into harmonized systems that capitalize on the strengths of individual disciplines. In essence, the horizon of hydroponics is not one of mere technical advancement but represents a holistic evolution, seamlessly melding technology, biology, and ecology. This review aims to provide a comprehensive overview of these trajectories, offering insights into the potentialities and promises that the future of hydroponics holds.
Exploring real-world symptom impact and improvement in well-being domains for tardive dyskinesia in VMAT2 inhibitor-treated patients via clinician survey and chart review
Authors: Meyer Jonathan M. , Chepke Craig , Bera Rimal B. , Pérez-Rodríguez M. Mercedes , Lundt Leslie , Franey Ericha G. , Dhanda Rahul , Benning Betsy , Bron Morgan , Yonan Chuck
Published: October 2023

Introduction

Two vesicular monoamine transporter 2 (VMAT2) inhibitors are approved in the United States (US) for the treatment of tardive dyskinesia (TD). There is a paucity of information on the impact of VMAT2 inhibitor treatment on patient social and physical well-being. The study objective was to elucidate clinician-reported improvement in symptoms and any noticeable changes in social or physical well-being in patients receiving VMAT2 inhibitors.

Methods

A web-based survey was offered to physicians, nurse practitioners, and physician assistants based in the US who prescribed valbenazine for TD within the past 24 months. Clinicians reported data from the charts of patients who met the inclusion criteria and were allowed to recall missing information.

Results

Respondents included 163 clinicians who reviewed charts of 601 VMAT2-treated patients with TD: 47% had TD symptoms in ≥2 body regions, with the most common being in the head or face and upper extremities. Prior to treatment, 93% of patients showed impairment in ≥1 social domain, and 88% were impaired in ≥1 physical domain. Following treatment, among those with improvement in TD symptoms (n = 540), 80% to 95% showed improvement in social domains, 90% to 95% showed improvement in physical domains, and 73% showed improvement in their primary psychiatric condition.

Discussion

In VMAT2-treated patients with TD symptom improvement, clinicians reported concomitant improvement in psychiatric disorder symptoms and in social and physical well-being. Regular assessment of TD impact on these types of domains should occur simultaneously with movement disorder ratings when evaluating the value of VMAT2 inhibitor therapy.
Kindergarten Vaccination Status in California After Changes to Medical Exemption Policy
Authors: Delamater Paul L. , Buttenheim Alison M. , Salmon Daniel A. , Schwartz Jason L. , Omer Saad B.
Published: October 2023

This study evaluates changes in medical exemptions and geographic distribution of kindergarteners in California not up to date on vaccination after changes to state legislation.
Survival Trend in Individuals With De Novo Metastatic Prostate Cancer After the Introduction of Doublet Therapy
Authors: Corsini Christian , Garmo Hans , Orrason Andri Wilberg , Gedeborg Rolf , Stattin Pär , Westerberg Marcus
Published: October 2023

Importance

Recently, life-prolonging treatments for patients with advanced prostate cancer have been introduced in clinical practice.

Objective

To investigate if the introduction of doublet therapy is associated with changes in survival on a population-basis.

Design, Setting, and Participants

This nationwide population-based cohort study used data from the Prostate Cancer data Base Sweden from 2008 to 2020. Men registered with de novo metastatic castration-sensitive prostate cancer (mCSPC) were included.

Exposure

The proportion of men with mCSPC who received doublet therapy, ie, androgen deprivation therapy plus androgen receptor pathway inhibitor drugs or chemotherapy was assessed.

Main Outcomes and Measures

Standardized overall survival, taking age, comorbidity, and cancer characteristics into consideration, was estimated by use of a parametric survival model.

Results

A total of 11 382 men were included in this study (median [IQR] age, 74.0 [68-81] years). There was a shift toward less advanced prostate cancer during the study period with a decrease in median (IQR) prostate-specific antigen at diagnosis in men with mCSPC from 145 (39-571) ng/mL to 107 (27-426) ng/mL. Upfront treatment with doublet therapy in these men simultaneously increased from 1% (7 of 991) in 2016 to 44% (402 of 922) in 2020. The adjusted 5-year overall survival increased from 26% (95% CI, 25%-28%) from 2008 to 2012 to 35% (95% CI, 31%-40%) from 2017 to 2020. During the first 5 years after diagnosis, there was an increase in mean survival of 6 months, from 2.7 (95% CI, 2.6-2.8) years from 2008 to 2012 to 3.2 (95% CI, 3.1-3.1) years from 2017 to 2020.

Conclusions and Relevance

In parallel with improvements in treatment of advanced prostate cancer, a clinically meaningful increase in mean survival was observed in men with de novo mCSPC in Sweden between 2008 and 2020 in this study.
Technical note: A collision prediction tool using Blender
Authors: Guyer Gian , Mueller Silvan , Wyss Yanick , Bertholet Jenny , Schmid Remo , Stampanoni Marco F. M. , Manser Peter , Fix Michael K.
Published: October 2023

Non‐coplanar radiotherapy treatment techniques on C‐arm linear accelerators have the potential to reduce dose to organs‐at‐risk in comparison with coplanar treatment techniques. Accurately predicting possible collisions between gantry, table and patient during treatment planning is needed to ensure patient safety. We offer a freely available collision prediction tool using Blender, a free and open‐source 3D computer graphics software toolset. A geometric model of a C‐arm linear accelerator including a library of patient models is created inside Blender. Based on the model, collision predictions can be used both to calculate collision‐free zones and to check treatment plans for collisions. The tool is validated for two setups, once with and once without a full body phantom with the same table position. For this, each gantry‐table angle combination with a 2° resolution is manually checked for collision interlocks at a TrueBeam system and compared to simulated collision predictions. For the collision check of a treatment plan, the tool outputs the minimal distance between the gantry, table and patient model and a video of the movement of the gantry and table, which is demonstrated for one use case. A graphical user interface allows user‐friendly input of the table and patient specification for the collision prediction tool. The validation resulted in a true positive rate of 100%, which is the rate between the number of correctly predicted collision gantry‐table combinations and the number of all measured collision gantry‐table combinations, and a true negative rate of 89%, which is the ratio between the number of correctly predicted collision‐free combinations and the number of all measured collision‐free combinations. A collision prediction tool is successfully created and able to produce maps of collision‐free zones and to test treatment plans for collisions including visualisation of the gantry and table movement.