bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Ischemic Optic Neuropathy and Internal Carotid Artery Dissection: A Systematic Review
Authors: Ripa Matteo , Shah Neeraj Apoorva , Schipa Chiara , Aceto Paola , Donati Tommaso
Published: April 2024

Background: To evaluate and review the current evidence regarding the association between ischemic optic neuropathy (ION) and internal carotid artery dissection (ICAD). Methods: We systematically reviewed studies according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (PRISMA), searching three databases (Scopus, Pubmed, and Embase) for relevant articles that clearly described the correlation between ION and ICAD. All studies that examined the association between ICAD and the development of ION were synthesized. Quality assessment using the Newcastle–Ottawa Scale (NOS) and Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports and Case Series were conducted. Results: Our search yielded 198 manuscripts published in the English language. Following study screening, fourteen studies were selected. The number of participants with ION following ICAD ranged from one to four, with sixteen patients experiencing either anterior ION, posterior ION, or a combination of both. The anterior or posterior ischemic optic neuropathy (AION and PION) patients’ ages were 48.75 ± 11.75 and 49.62 ± 12.85, respectively. Fourteen out of sixteen patients experienced spontaneous ICAD, whereas the traumatic etiology was ascertained in two patients. Conclusions: Hence, albeit rare, ophthalmologists should consider ICAD a potential cause of ION, especially in young adults with concomitant cephalic pain and vision reduction.
Increased Risk of Breakthrough SARS-CoV-2 Infections in Patients with Colorectal Cancer: A Population-Based Propensity-Matched Analysis
Authors: Alsakarneh Saqr , Jaber Fouad , Qasim Hana , Massad Abdallah , Alzghoul Hamza , Abboud Yazan , Dahiya Dushyant Singh , Bilal Mohammad , Shaukat Aasma
Published: April 2024

Background/Objectives: This study aimed to investigate the association between colorectal cancer (CRC) and the risk of breakthrough respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vaccinated patients with CRC. Methods: This retrospective cohort study used the TriNetX research network to identify vaccinated patients with CRC. Patients were matched using propensity score matching (PSM) and divided into patients with CRC and control (without history of CRC) groups. The primary outcome was the risk of breakthrough SARS-CoV-2 in vaccinated patients. The secondary outcome was a composite of all-cause emergency department (ED) visits, hospitalization, and death during the follow-up period after the diagnosis of COVID-19. Results: A total of 15,416 vaccinated patients with CRC were identified and propensity matched with 15,416 vaccinated patients without CRC. Patients with CRC had a significantly increased risk for breakthrough infections compared to patients without CRC (aOR = 1.78; [95% CI: 1.47–2.15]). Patients with CRC were at increased risk of breakthrough SARS-CoV-2 infections after two doses (aOR = 1.71; [95% CI: 1.42–2.06]) and three doses (aOR = 1.36; [95% CI: 1.09–1.69]) of SARS-CoV-2 vaccine. Vaccinated patients with CRC were at a lower risk of COVID-19 infection than unvaccinated CRC patients (aOR = 0.342; [95% CI: 0.289–0.404]). The overall composite outcome (all-cause ED visits, all-cause hospitalization, and all-cause death) was 51.6% for breakthrough infections, which was greater than 44.3% for propensity score-matched patients without CRC (aOR = 1.79; [95% CI: 1.29–2.47]). Conclusions: This cohort study showed significantly increased risks for breakthrough SARS-CoV-2 infection in vaccinated patients with CRC. Breakthrough SARS-CoV-2 infections in patients with CRC were associated with significant and substantial risks for hospitalizations.
Incidence of a Multicomponent Physical Exercise Program on Body Composition in Overweight or Obese People Aged 60 Years or Older from Chile
Authors: Pleticosic-Ramírez Yazmina , Mecías-Calvo Marcos , Arufe-Giráldez Víctor , Navarro-Patón Rubén
Published: April 2024

This research aimed to explore the changes produced in body mass index (BMI), fat mass percentage (FMP), muscle mass percentage (MMP), and visceral fat percentage (VFP) in 60-year-old or over overweight or obese people after a multicomponent exercise program. This quasi-experimental study involved 70 overweight or obese older people between 60 and 86 years old (M = 73.15; SD = 5.94) who were randomly assigned to a control group (CG, n = 35) and an experimental group (EG, n = 35). At the beginning and at the end of the intervention program, anthropometric and body composition data were collected. The results showed an increase in BMI after the intervention in the CG (p = 0.010) and a decrease in the EG (p < 0.001). The results regarding the FMP indicate a significant decrease in the EG (p < 0.001) after the intervention, as occurs with the VFP (p = 0.003). The MMP increased in the EG (p < 0.001) after the intervention program. Regarding gender, statistically significant differences were found in the MMP after the intervention (p = 0.025), with higher percentages in men in the EG. VFP decreased in both men (p = 0.005) and women (p = 0.019) in the EG. From the results obtained, we can say that a 6-month multicomponent program produces a decrease in BMI, FMP, and VFP and an increase in MMP in its participants. This type of intervention seems to produce a greater increase in muscle mass in men than in women and a decrease in VFP in both genders.
Characteristics and Environmental Indications of Grain Size and Magnetic Susceptibility of the Late Quaternary Sediments from the Xiyang Tidal Channel, Western South Yellow Sea
Authors: Xia Fei , Liu Dezheng , Zhang Yongzhan
Published: April 2024

To reveal the characteristics and environmental indications for the combination of the grain size and magnetic susceptibility of coastal sediments, we provided a necessary basis for further study on their genetic mechanisms. Based on the data of grain size and magnetic susceptibility of the 36.10 m long core 07SR01 sediments in the Xiyang tidal channel of western South Yellow Sea, we analyzed their variations and correlations and further revealed their environmental indications and corresponding regional sedimentary evolution via the combination of the aforementioned analysis results, the reinterpretation results of the sedimentary sequence and the age of core 07SR01 and shallow seismic profiles, and the findings of climate and glacial–eustatic cycles during Late Quaternary. The three stages of the sedimentary evolution of the Xiyang tidal channel between marine isotope stage (MIS) 7 and MIS 5 were summarized as follows: First is the stage of marginal bank and riverbed developments in the tidal estuary under a relatively high sea level and strong hydrodynamic conditions during MIS 7 (core section: 36.10–26.65 m). The sediments deposited in this stage were mainly affected by the paleo-Changjiang River and characterized by a coarse grain size (mean: 4.02 Φ) and relatively high magnetic susceptibilities (mean: 27.06 × 10−8 m3·kg−1), with small fluctuations which were strongly and positively correlated with the sand component. Second is the stage dominated by fluviolacustrine and littoral environments with the weak hydrodynamics during MIS 6–5, in which the climate changed from cold and dry to warm and humid as the sea level rose after a drop (core section: 26.65–15.77 m). The sediments deposited in this stage were characterized by a fine grain size (mean: 5.27 Φ) and low magnetic susceptibilities with minor variations (mean: 10.83 × 10−8 m3·kg−1) which were weakly and positively correlated with the coarse silt component. Third is the stage of delta front in the tidal estuary with a relatively high sea level and strong hydrodynamics during MIS 5 (core section: 15.77–0 m). The sediments deposited in this stage were strongly influenced by the paleo-Yellow River and characterized by a relatively coarse grain size (mean: 4.86 Φ), and high magnetic susceptibilities (mean: 37.15 × 10−8 m3·kg−1) with large fluctuations which were weakly and positively correlated with the sand and coarse silt components.
Numerical Study on the Swimming and Energy Self-Sufficiency of Multi-Joint Robotic Fish
Authors: Liang Guodu , Xin Zhiqiang , Ding Quanlin , Liu Songyang , Ren Liying
Published: April 2024

Energy is one of the primary challenges in the long-term operation of robotic fish. The research on combining wave energy-harvesting technology with robotic fish for energy supplementation is not extensive, and there is insufficient comprehensive analysis on energy harvesting from waves and energy costs during swimming. Therefore, the energy self-sufficiency of multi-joint robotic fish is investigated by employing the coupling method of smoothed particle hydrodynamics (SPH) and multi-body dynamics in this study. A reversible energy conversion mechanism is applied to the robotic fish, serving as a driving system during swimming and as a power take-off (PTO) system during energy harvesting. The energy costs of the multi-joint robotic fish under various undulation parameters (including amplitude, frequency, and body wavelength) are analyzed, along with an examination of the influence of the PTO system on energy harvesting. The results show that, compared to the undulation amplitude and body wavelength, the undulation frequency has the greatest impact on swimming efficiency and energy costs, with low-frequency swimming being advantageous for efficient energy utilization. Additionally, the damping coefficient of the PTO system directly affects energy-harvesting efficiency, with higher energy-harvesting power achievable with an optimal PTO system parameter. Through a comprehensive analysis of energy costs and energy harvesting, it is concluded that the achievement of energy self-sufficiency for multi-joint robotic fish in marine environments is highly feasible.
Corona-Associated Mucormycosis: Case Series Reports and Review of the Literature
Authors: Fitero Andreea , Negrut Nicoleta , John Harrie Toms , Ferician Anca , Marian Paula
Published: April 2024

During the COVID-19 pandemic, a significant increase in cases of mucormycosis was observed in COVID-19 patients, especially in India, but not exclusively. The presented cases highlight the heterogeneous nature of mucormycosis, emphasizing the importance of recognizing predisposing factors, such as immunosuppression, due to comorbidities or medication. Diagnosing mucormycosis poses a challenge due to nonspecific clinical manifestations, requiring a multidisciplinary approach for accurate diagnosis. Treatment involves a multi-pronged approach centered around the early initiation of antifungal therapy alongside surgical intervention and the management of underlying conditions, with an emphasis on controlling immunosuppression. Understanding the relationship between COVID-19 and predisposing factors for mucormycosis is fundamental for developing prevention and treatment strategies.
The Diversity and Community Composition of Three Plants’ Rhizosphere Fungi in Kaolin Mining Areas
Authors: Xiao Wenqi , Zhang Yunfeng , Chen Xiaodie , Sha Ajia , Xiong Zhuang , Luo Yingyong , Peng Lianxin , Zou Liang , Zhao Changsong , Li Qiang
Published: April 2024

Mining activities in the kaolin mining area have led to the disruption of the ecological health of the mining area and nearby soils, but the effects on the fungal communities in the rhizosphere soils of the plants are not clear. Three common plants (Conyza bonariensis, Artemisia annua, and Dodonaea viscosa) in kaolin mining areas were selected and analyzed their rhizosphere soil fungal communities using ITS sequencing. The alpha diversity indices (Chao1, Shannon, Simpson, observed-species, pielou-e) of the fungal communities decreased to different extents in different plants compared to the non-kauri mining area. The β-diversity (PCoA, NMDS) analysis showed that the rhizosphere soil fungal communities of the three plants in the kaolin mine area were significantly differentiated from those of the control plants grown in the non-kaolin mine area, and the extent of this differentiation varied among the plants. The analysis of fungal community composition showed that the dominant fungi in the rhizosphere fungi of C. bonariensis and A. annua changed, with an increase in the proportion of Mycosphaerella (genus) by about 20% in C. bonariensis and A. annua. An increase in the proportion of Didymella (genus) by 40% in D. viscosa was observed. At the same time, three plant rhizosphere soils were affected by kaolin mining activities with the appearance of new fungal genera Ochrocladosporium and Plenodomus. Predictive functional potential analysis of the samples revealed that a significant decrease in the potential of functions such as biosynthesis and glycolysis occurred in the rhizosphere fungal communities of kaolin-mined plants compared to non-kaolin-mined areas. The results show that heavy metals and plant species are the key factors influencing these changes, which suggests that selecting plants that can bring more abundant fungi can adapt to heavy metal contamination to restore soil ecology in the kaolin mining area.
Discovery of a Unique Set of Dog-Seroreactive Coccidioides Proteins Using Nucleic Acid Programmable Protein Array
Authors: Koehler Megan A. , Song Lusheng , Grill Francisca J. , Shubitz Lisa F. , Powell Daniel A. , Galgiani John N. , Orbach Marc J. , Robb Edward J. , Chung Yunro , Williams Stacy A. , Murugan Vel , Park Jin-gyoon , LaBaer Joshua , Lake Douglas F. , Magee D. Mitchell
Published: April 2024

Valley Fever (VF), caused by fungi in the genus Coccidioides, is a prevalent disease in southwestern and western parts of the United States that affects both humans and animals, such as dogs. Although the immune responses to infection with Coccidioides spp. are not fully characterized, antibody-detection assays are used in conjunction with clinical presentation and radiologic findings to aid in the diagnosis of VF. These assays often use Complement Fixation (CF) and Tube Precipitin (TP) antigens as the main targets of IgG and IgM reactivity, respectively. Our group previously reported evidence of over 800 genes expressed at the protein level in C. posadasii. However, antibody reactivity to the majority of these proteins has never been explored. Using a new, high-throughput screening technology, the Nucleic Acid Programmable Protein Array (NAPPA), we screened serum specimens from dogs against 708 of these previously identified proteins for IgG reactivity. Serum from three separate groups of dogs was analyzed and revealed a small panel of proteins to be further characterized for immuno-reactivity. In addition to CF/CTS1 antigen, sera from most infected dogs showed antibody reactivity to endo-1,3-betaglucanase, peroxisomal matrix protein, and another novel reactive protein, CPSG_05795. These antigens may provide additional targets to aid in antibody-based diagnostics.
High Risk, Constrained Return: Impact of Student Loans on Agricultural Real Estate
Authors: Diosdado Leobardo , Lacombe Donald , Hudson Darren
Published: April 2024

A farming household’s decision to continue producing agricultural commodities within the United States is influenced by a multitude of factors. Thus, this study seeks to examine whether the outstanding student loan balance of any member within a farming household may explain why the total number of acres devoted to the production of agriculture in the United States continues to decline. Panel data from the 2007–2009 Survey of Consumer Finances are analyzed via a fixed effect model to estimate the effect of outstanding student loan balances on farmland acreage owned, controlling for other factors like farm income, debt, and land prices. The results suggest that for each additional dollar of outstanding student loan debt, there is an associated decrease of 0.0064 acres in total farmland ownership. This suggests that student loan debt may also be a factor in the decline in real estate devoted to agriculture production. The estimated effect is both economically and statistically significant. This study contributes to the literature on the risks and constraints associated with farming households that own or seek to procure additional acres of agricultural producing real estate.
Transformation of the Ukrainian Stock Market: A Data Properties View
Authors: Plastun Alex , Hariaha Lesia , Yatsenko Oleksandr , Hasii Olena , Sliusareva Liudmyla
Published: April 2024

This paper investigates the evolution of the Ukrainian stock market through an analysis of various data properties, including persistence, volatility, normality, and resistance to anomalies for the case of daily returns from the PFTS stock index spanning 1995–2022. Segmented into sub-periods, it aims to test the hypothesis that the market’s efficiency has increased over time. To do this different statistical techniques and methods are used, including R/S analysis, ANOVA analysis, regression analysis with dummy variables, t-tests, and others. The findings present a mixed picture: while volatility and persistence demonstrate a general decreasing trend, indicating a potential shift towards a more efficient market, normality tests reveal no discernible differences between analyzed periods. Similarly, the analysis of anomalies shows no specific trends in the market’s resilience to the day-of-the-week effect. Overall, the results suggest a lack of systematic changes in data properties in the Ukrainian stock market over time, possibly due to the country’s volatile conditions, including two revolutions, economic crises, the annexation of territories, and a Russian invasion leading to the largest war in Europe since WWII. The limited impact of reforms and changes justifies the need for continued market reform and evolution post-war.
Spatiotemporal Pattern and Drivers of Ecological Quality in Inner Mongolia
Authors: Li Shouwei , Qu Shufeng , Zhang Guoming , Zhou Yuantao , Sun Xuran , Li Jiaxue , Zhang Shanshan
Published: April 2024

With the escalating global climate change and frequent human activities, Inner Mongolia, as a crucial ecological barrier in the Beijing-Tianjin-Hebei region, Bohai Economic Rim, and even the whole country, confronts many ecosystem issues. To reveal the intricate interplay between natural processes, human activities, and policy interventions shaping the region’s ecological landscape, we provide a comprehensive analysis of ecological quality in Inner Mongolia from 2002 to 2021. Key findings include: (1) The research uncovers an overall improvement in ecological quality across Inner Mongolia, albeit with certain regions exhibiting a pattern of deterioration followed by improvement, particularly notable in the central part of the province. (2) Cropland, shrub, grassland, barren, wetland, and water are decreasing, while impervious, and forestland are increasing. (3) Precipitation, temperature, and elevation are significant drivers affecting the quality of the ecological environment. Interestingly, while human production and activities have altered ecological conditions, factors like GDP, population density, and night lighting index do not directly impact environmental quality significantly. This underscores the intricate interplay among various factors within the socioeconomic system, highlighting its complexity. (4) Based on these findings, our policy recommendations include strengthening ecological monitoring and management, promoting sustainable urban development, conducting public education and awareness campaigns, and fostering stakeholder collaboration for data sharing and collective understanding. Adopting sustainable management strategies is essential for promoting ecological resilience and mitigating environmental degradation in Inner Mongolia, not only benefiting the local ecosystem but also contributing to national and global environmental well-being.
Early Identification and Dynamic Stability Evaluation of High-Locality Landslides in Yezhi Site Area, China by the InSAR Method
Authors: Lian Baoqin , Wang Daozheng , Wang Xingang , Tan Weijia
Published: April 2024

In mountainous regions, high-locality landslides have the characteristics of a latent disaster process with a wide disaster range, which can easily cause large casualties. Therefore, early landslide identification and dynamic stability evaluation are significant. We first used multi-temporal synthetic aperture radar data to detect potential landslides at Yezhi Site Area during the 2015–2020 period, identifying and mapping a total of 18 active landslides. The study area was found to have an average deformation rate between −15 and 10 mm/y during the period. Then, time series and spatiotemporal deformation characteristics of landslides were examined using interferogram stacking and small baseline interferometry techniques. The results show that the majority of the landslide deformations detected exhibit a periodic variation trend, and the study area was in a slow deformation state before 2017. Finally, combined with detection results, Google Earth optical images, and field investigations, it is concluded that the main factors affecting the time series deformation and spatial distribution of landslides in the study area are rainfall, geological factors, and engineering activities. The results of this study provide valuable technical references and support for early identification and dynamic stability evaluation of regional active landslides in complex terrain, especially for high-locality landslides.
Mechanical Behavior of Selective Laser Melting (SLM) Parts with Varying Thicknesses in a Saline Environment under Different Exposure Times
Authors: Akhtar Maaz , Samiuddin Muhammad , Muzamil Muhammad , Siddiqui Muhammad Ali , Khan Rashid , Alsaleh Naser A. , Siddiqui Ali Khursheed , Djuansjah Joy , Majeed Arfan
Published: April 2024

A promising method for additive manufacturing that makes it possible to produce intricate and personalized parts is selective laser melting (SLM). However, the mechanical properties of as-corroded SLM parts are still areas of concern. This research investigates the mechanical behavior of SLM parts that are exposed to a saline environment containing a 3.5% NaCl solution for varying lengths of time. The exposure times chosen for this study were 10 days, 20 days, and 30 days. The results reveal that the tensile strength of the parts is significantly affected by the duration of exposure. Additionally, the study also examined the influence of porosity on the corrosion behavior of the parts. The analysis included studying the mass loss of the parts over time, and a regression analysis was conducted to analyze the relationship between exposure time and mass loss. In addition, the utilization of scanning electron microscopy (SEM) and X-ray photo spectroscopy (XPS) techniques yielded valuable insights into the fundamental mechanisms accountable for the observed corrosion and mechanical behavior. It was found that the presence of corrosion products (i.e., oxide layer) and pitting contributed to the degradation of the SLM parts in the saline environment. This research emphasizes the importance of considering part thickness in the design of SLM components for corrosive environments and provides insights for enhancing their performance and durability.
On an Anisotropic Logistic Equation
Authors: Gasiński Leszek , Papageorgiou Nikolaos S.
Published: April 2024

We consider a nonlinear Dirichlet problem driven by the (p(z),q)-Laplacian and with a logistic reaction of the equidiffusive type. Under a nonlinearity condition on a quotient map, we show existence and uniqueness of positive solutions and the result is global in parameter λ. If the monotonicity condition on the quotient map is not true, we can no longer guarantee uniqueness, but we can show the existence of a minimal solution uλ* and establish the monotonicity of the map λ⟼uλ* and its asymptotic behaviour as the parameter λ decreases to the critical value λ^1(q)>0 (the principal eigenvalue of (−Δq,W01,q(Ω))).
Non-Invasive Diagnostic Tests for Portal Hypertension in Patients with HBV- and HCV-Related Cirrhosis: A Comprehensive Review
Authors: Celsa Ciro , Veneziano Marzia , Di Giorgio Francesca Maria , Cannova Simona , Lombardo Antonino , Errigo Emanuele , Landro Giuseppe , Simone Fabio , Sinagra Emanuele , Calvaruso Vincenza
Published: April 2024

Clinically significant portal hypertension (CSPH) in patients with compensated advanced chronic liver disease indicates an increased risk of decompensation and death. While invasive methods like hepatic venous–portal gradient measurement is considered the gold standard, non-invasive tests (NITs) have emerged as valuable tools for diagnosing and monitoring CSPH. This review comprehensively explores non-invasive diagnostic modalities for portal hypertension, focusing on NITs in the setting of hepatitis B and hepatitis C virus-related cirrhosis. Biochemical-based NITs can be represented by single serum biomarkers (e.g., platelet count) or by composite scores that combine different serum biomarkers with each other or with demographic characteristics (e.g., FIB-4). On the other hand, liver stiffness measurement and spleen stiffness measurement can be assessed using a variety of elastography techniques, and they can be used alone, in combination with, or as a second step after biochemical-based NITs. The incorporation of liver and spleen stiffness measurements, alone or combined with platelet count, into established and validated criteria, such as Baveno VI or Baveno VII criteria, provides useful tools for the prediction of CSPH and for ruling out high-risk varices, potentially avoiding invasive tests like upper endoscopy. Moreover, they have also been shown to be able to predict liver-related events (e.g., the occurrence of hepatic decompensation). When transient elastography is not available or not feasible, biochemical-based NITs (e.g., RESIST criteria, that are based on the combination of platelet count and albumin levels) are valid alternatives for predicting high-risk varices both in patients with untreated viral aetiology and after sustained virological response. Ongoing research should explore novel biomarkers and novel elastography techniques, but current evidence supports the utility of routine blood tests, LSM, and SSM as effective surrogates in diagnosing and staging portal hypertension and predicting patient outcomes.
Serum Malondialdehyde-Modified Low-Density Lipoprotein as a Risk Marker for Peripheral Arterial Stiffness in Maintenance Hemodialysis Patients
Authors: Liu Wei-Nung , Hsu Yi-Chiung , Lu Chia-Wen , Lin Ssu-Chin , Wu Tsung-Jui , Lin Gen-Min
Published: April 2024

Background and Objectives: Peripheral arterial stiffness (PAS), assessed by brachial-ankle pulse wave velocity (baPWV), is an independent biomarker of cardiovascular diseases (CVD) in patients on maintenance hemodialysis (HD). Malondialdehyde-modified low-density lipoprotein (MDA-LDL), an oxidative stress marker, has been linked to atherosclerosis and CVD. However, the association between serum MDA-LDL and PAS among HD patients has not been fully elucidated. This study aimed to examine the association of serum MDA-LDL with PAS in HD patients and to identify the optimal cutoff value of serum MDA-LDL for predicting PAS. Materials and Methods: A cross-sectional study was conducted in 100 HD patients. Serum MDA-LDL was quantified using an enzyme-linked immunosorbent assay (ELISA), and baPWV was measured using a volume plethysmographic device. Patients were divided into the PAS group (baPWV > 18.0 m/s) and the non-PAS group (baPWV ≤ 18.0 m/s). The associations of baPWV and other clinical and biochemical parameters with serum MDA-LDL were assessed by multivariable logistic regression analyses. A receiver operating characteristic (ROC) curve analysis was performed to determine the optimal cutoff value of serum MDA-LDL for predicting PAS. Results: In multivariable logistic regression analysis, higher serum MDA-LDL, older age, and higher serum C-reactive protein [odds ratios (ORs) and 95% confidence intervals: 1.014 (1.004–1.025), 1.044 (1.004–1.085) and 3.697 (1.149–11.893)] were significantly associated with PAS. In the ROC curve analysis, the optimal cutoff value of MDA-LDL for predicting PAS was 80.91 mg/dL, with a sensitivity of 79.25% and a specificity of 59.57%. Conclusions: Greater serum MDA-LDL levels, particularly ≥80.91 mg/dL, were independently associated with PAS in HD patients. The findings suggest that oxidative stress plays a crucial role in the pathogenesis of PAS, and targeting MDA-LDL may be a potential therapeutic strategy for reducing cardiovascular risk in HD patients.
Immobilization of Perylenetetracarboxylic Dianhydride on Al2O3 for Efficiently Photocatalytic Sulfide Oxidation
Authors: Liang Jiahao , Wang Jie , Hou Hao , Xu Qingzhu , Liu Wei , Su Chenliang , Sun Hongli
Published: April 2024

Perylenetetracarboxylic dianhydride (PTCDA) derivatives have received significant attention as molecule photocatalysts. However, the poor recyclability of molecule-type photocatalysts hinders their widespread applications. Herein, immobilization of PTCDA on Al2O3 was achieved by simply physical mixing, which not only dramatically improved their recyclability, but also surprisingly improved the reactivity. A mechanism study suggested that the photo-exited state (PTCDA*) of PTCDA could promote the oxidation of thioanisole to generate PTCDA•−, which sequentially reduces oxygen to furnish superoxide radicals to achieve the catalytic cycle. Herein, the immobilization support Al2O3 was able to facilitate the strong adsorption of thioanisole, thereby boosting the photocatalytic activity. This work provides a new insight that the immobilization of organic molecular photocatalysts on those supports with proper adsorption sites could furnish highly efficient, stable, and recyclable molecular-based heterogeneous photocatalysts.
Nanoporous Au Behavior in Methyl Orange Solutions
Authors: Pinna Andrea , Pia Giorgio , Melis Nicola , Prato Mirko , Cutrufello Maria Giorgia , Sogne Elisa , Falqui Andrea , Pilia Luca
Published: April 2024

Nanoporous (NP) gold, the most extensively studied and efficient NP metal, possesses exceptional properties that make it highly attractive for advanced technological applications. Notably, its remarkable catalytic properties in various significant reactions hold enormous potential. However, the exploration of its catalytic activity in the degradation of water pollutants remains limited. Nevertheless, previous research has reported the catalytic activity of NP Au in the degradation of methyl orange (MO), a toxic azo dye commonly found in water. This study aims to investigate the behavior of nanoporous gold in MO solutions using UV-Vis absorption spectroscopy and high-performance liquid chromatography. The NP Au was prepared by chemical removal of silver atoms of an AuAg precursor alloy prepared by ball milling. Immersion tests were conducted on both pellets and powders of NP Au, followed by examination of the residual solutions. Additionally, X-ray photoelectron spectroscopy and electrochemical impedance measurements were employed to analyze NP Au after the tests. The findings reveal that the predominant and faster process involves the partially reversible adsorption of MO onto NP Au, while the catalytic degradation of the dye plays a secondary and slower role in this system.
Mechanochemical Solid-State Immobilization of Photofunctional Dyes on Amorphous Silica Particles and Investigation of Their Interactive Mechanisms
Authors: Kimura Reo , Chatani Sunao , Inui Masahiko , Motozuka Satoshi , Yamada Iori , Tagaya Motohiro
Published: April 2024

Amorphous silica particles (ASPs) have been reported to exhibit bioactive properties and are becoming the focus of attention as bioceramics. However, their interactions with proteins in living organisms remain to be understood and need to be investigated in order to achieve wider applications. Our research group found that chlorine (Cl)-containing ASPs are useful for protein immobilization. Photofunctional dyes (fluorescein (FS−), methylene blue (MB+)) that have the carboxy and amino groups as the main functional groups were immobilized on the Cl-containing ASPs via the mechanochemical method as the model molecule and their spectral properties were used to investigate and discuss the organic/inorganic interfacial bonding states. In FS−, the oxygen atoms of the carboxy groups in the molecule were immobilized by the hydrogen bonds with the silanol groups on the ASPs surfaces, indicating that there is an optimum Cl content for the immobilization as the monomer state. In the case of MB+, as the Cl concentration in the ASPs increases, the immobilization via the electrostatic interactions between the Cl in the ASPs and the terminal dimethylamino group, and the hydrogen bonding between the N atoms of the MB+ hetero ring and the particle silanol group were enhanced. These results mainly suggest that the protein adsorption system occurs through the hydrogen bonding between the carboxy groups of the protein and the silanol groups on the particles and via electrostatic interactions between the amino groups of the protein and the dissociated silanol groups and the contained Cl at the particles. Thus, the spectral characterization using dyes as probes is expected to predict the protein interactions with the amorphous silica particles.
A Systematic Genotoxicity Assessment of a Suite of Metal Oxide Nanoparticles Reveals Their DNA Damaging and Clastogenic Potential
Authors: Solorio-Rodriguez Silvia Aidee , Wu Dongmei , Boyadzhiev Andrey , Christ Callum , Williams Andrew , Halappanavar Sabina
Published: April 2024

Metal oxide nanoparticles (MONP/s) induce DNA damage, which is influenced by their physicochemical properties. In this study, the high-throughput CometChip and micronucleus (MicroFlow) assays were used to investigate DNA and chromosomal damage in mouse lung epithelial cells induced by nano and bulk sizes of zinc oxide, copper oxide, manganese oxide, nickel oxide, aluminum oxide, cerium oxide, titanium dioxide, and iron oxide. Ionic forms of MONPs were also included. The study evaluated the impact of solubility, surface coating, and particle size on response. Correlation analysis showed that solubility in the cell culture medium was positively associated with response in both assays, with the nano form showing the same or higher response than larger particles. A subtle reduction in DNA damage response was observed post-exposure to some surface-coated MONPs. The observed difference in genotoxicity highlighted the mechanistic differences in the MONP-induced response, possibly influenced by both particle stability and chemical composition. The results highlight that combinations of properties influence response to MONPs and that solubility alone, while playing an important role, is not enough to explain the observed toxicity. The results have implications on the potential application of read-across strategies in support of human health risk assessment of MONPs.
Nitrogen-Doped Porous Carbon Derived from Covalent Triazine Framework for Catalytic Oxidation of Benzyl Alcohol
Authors: Pan Xin , Zhu Yanan , Yang Yongchang , Zhu Qianqian
Published: April 2024

The catalytic oxidation of alcohols is an important transformation in the chemical industry. Carbon materials with a large surface area and N doping show great promise as metal-free catalysts for the reaction. In this study, a rich N-containing covalent triazine framework polymerized by cyanuric chloride and p-phenylenediamine was used to synthesize N-doped porous carbon with the assistance of a pore-forming agent—NaCl. First, the mass ratio of the polymer/NaCl was optimized to 1:9. Then, the influence of the pyrolysis temperatures (700–1000 °C) on the materials was studied in detail. It was found that the carbon materials were gradually exfoliated by molten salt at high temperatures. XRD and Raman characterizations showed them with a certain graphitization. The optimal doped carbon CNN-1-9-900 achieved the highest surface area of 199.03 m2g−1 with the largest pore volume of 0.29 cm3g−1. Furthermore, it had a high N content of 9.9 at% with the highest relative proportion of pyridinic/graphitic N. Due to the synergistic effect between the surface area and pyridinic/graphitic N, CNN-1-9-900 showed the best performance for benzyl alcohol oxidation with TBHP at moderate conditions, and the process also worked for its derivatives.
Linear Fiber Laser Configurations for Optical Concentration Sensing in Liquid Solutions
Authors: Soares Liliana , Perez-Herrera Rosa Ana , Novais Susana , Ferreira António , Silva Susana , Frazão Orlando
Published: April 2024

In this study, different configurations based on linear fiber lasers were proposed and experimentally demonstrated to measure the concentration of liquid solutions. Samples of paracetamol liquid solutions with different concentrations, in the range from 52.61 to 201.33 g/kg, were used as a case-study. The optical gain was provided by a commercial bidirectional Erbium-Doped Fiber Amplifier (EDFA) and the linear cavity was obtained using two commercial Fiber Bragg Gratings (FBGs). The main difference of each configuration was the coupling ratio of the optical coupler used to extract the system signal. The sensing head corresponded to a Single-Mode Fiber (SMF) tip that worked as an intensity sensor. The results reveal that, despite the optical coupler used (50:50, 60:40, 70:30 or 80:20), all the configurations reached the laser condition, however, the concentration sensing was only possible using a laser drive current near to the threshold value. The configurations using a 70:30 and an 80:20 optical coupler allowed paracetamol concentration measurements with a higher sensitivity of (−3.00 ± 0.24) pW/(g/kg) to be performed. In terms of resolution, the highest value obtained was 1.75 g/kg, when it was extracted at 20% of the output power to the linear cavity fiber laser configuration.
Complex Environment Based on Improved A* Algorithm Research on Path Planning of Inspection Robots
Authors: Zhang Yilin , Zhao Qiang
Published: April 2024

The proposed research aims to accomplish an improved A* algorithm for mobile robots in complex environments. In this novel algorithm, the guidance of environment information is added to the evaluation function to enhance the adaptability of the algorithm in complex environments. Additionally, to solve the problem of path smoothness, the optimal selection rules for child nodes and the bidirectional optimization strategy for path smoothing are introduced to reduce redundant nodes, which effectively makes the search space smaller and the path smoother. The simulation experiments show that, compared with the colony algorithm and Dijkstra algorithms, the proposed algorithm has significantly improved performance. Compared with the A* algorithm, the average planning time is reduced by 17.2%, the average path length is reduced by 2.05%, the average turning point is reduced by 49.4%, and the average turning Angle is reduced by 75.5%. The improved A* algorithm reduces the search space by 61.5% on average. The simulation results show that the effectiveness and adaptability of the improved A* algorithm in complex environments are verified by multi-scale mapping and multi-obstacle environment simulation experiments.
Buddhist Cultural Exchange between Paekche and Ancient Japan: A Comparative Analysis of the Archaeological Remains from the Wooden Pagoda Site at Asukadera and Śarīra Reliquaries from Paekche Temple Sites
Authors: Lee Byongho , Naoto Isahaya
Published: April 2024

This article provides a critical review of the results of the Asuka Historical Museum’s excavation of the Asukadera wooden pagoda site in Japan since 2015, and its implications for Buddhist cultural exchange in East Asia. The second section examines the Asuka Historical Museum’s categorization and scientific analysis of the beads, pearls, horse gear, earrings, gold and silver artifacts, mica, and śarīra containers. We assert that most objects excavated from the Asukadera wooden pagoda site are relics from the Asuka era (538–710), when the pagoda was first established in 593, and only a limited number of artifacts, such as the śarīra [relics] container, were added after the wooden pagoda was burned down in 1196. The third section compares the archeological remains from the Asukadera wooden pagoda site and the reliquary objects from the Paekche Wanghŭng-sa site (577) and Mirŭk-sa site (639), which have been conventionally considered to be its models. What the relics from these three historical sites have in common is that they include clothing accessories nobles wore as they participated in the Buddhist rituals of enshrining the śarīra in a wooden pagoda. However, some differences in the metallic craft items, such as crowns and belts, were still found between Paekche and Japan, which was due to the difference in costume styles in the respective countries at the time. Also, horse gear and lamellar armor unearthed from Asukadera sites was not found in Paekche temple sites, but is similar to earlier Japanese kofun (megalithic tumuli) grave goods, which provides evidence that as Buddhism was transferred to Japan from Paekche, it was not accepted in completely the same form.
Improvement of Phased Antenna Array Applied in Focused Microwave Breast Hyperthermia
Authors: Wang Xuanyu , Xi Zijun , Ye Ke , Gong Zheng , Chen Yifan , Wang Xiong
Published: April 2024

Focused microwave breast hyperthermia (FMBH) employs a phased antenna array to perform beamforming that can focus microwave energy at targeted breast tumors. Selective heating of the tumor endows the hyperthermia treatment with high accuracy and low side effects. The effect of FMBH is highly dependent on the applied phased antenna array. This work investigates the effect of polarizations of antenna elements on the microwave-focusing results by simulations. We explore two kinds of antenna arrays with the same number of elements using different digital realistic human breast phantoms. The first array has all the elements’ polarization in the vertical plane of the breast, while the second array has half of the elements’ polarization in the vertical plane and the other half in the transverse plane, i.e., cross polarization. In total, 96 sets of different simulations are performed, and the results show that the second array leads to a better focusing effect in dense breasts than the first array. This work is very meaningful for the potential improvement of the antenna array for FMBH, which is of great significance for the future clinical applications of FMBH. The antenna array with cross polarization can also be applied in microwave imaging and sensing for biomedical applications.
Evaluating Vascular Depth-Dependent Changes in Multi-Wavelength PPG Signals Due to Contact Force
Authors: Lambert Cause Joan , Solé Morillo Ángel , da Silva Bruno , García-Naranjo Juan C. , Stiens Johan
Published: April 2024

Photoplethysmography (PPG) is a non-invasive method used for cardiovascular monitoring, with multi-wavelength PPG (MW-PPG) enhancing its efficacy by using multiple wavelengths for improved assessment. This study explores how contact force (CF) variations impact MW-PPG signals. Data from 11 healthy subjects are analyzed to investigate the still understudied specific effects of CF on PPG signals. The obtained dataset includes simultaneous recording of five PPG wavelengths (470, 525, 590, 631, and 940 nm), CF, skin temperature, and the tonometric measurement derived from CF. The evolution of raw signals and the PPG DC and AC components are analyzed in relation to the increasing and decreasing faces of the CF. Findings reveal individual variability in signal responses related to skin and vasculature properties and demonstrate hysteresis and wavelength-dependent responses to CF changes. Notably, all wavelengths except 631 nm showed that the DC component of PPG signals correlates with CF trends, suggesting the potential use of this component as an indirect CF indicator. However, further validation is needed for practical application. The study underscores the importance of biomechanical properties at the measurement site and inter-individual variability and proposes the arterial pressure wave as a key factor in PPG signal formation.
Batch Specular Plane Flatness Measurements Based on Phase Measuring Deflectometry
Authors: Li Zhuotong , Wang Dongxue , Liu Lei , Zhang Xiaodong
Published: April 2024

Flatness is a critical parameter in the manufacturing industry, directly impacting the fit and overall product performance. As the efficiency of manufacturing continues to advance, there is an increasing demand for more accurate and efficient measurement techniques. Existing methods often struggle to strike a balance between precision and efficiency. In response, this article introduces a novel approach that is capable of achieving high-precision and rapid measurements concerning multiple surfaces. By enhancing the traditional phase measuring deflectometry (PMD) method, employing a matching technique based on polar lines and normal vector constraints to address discrete surface measurement challenges, and implementing a plane pre-positioning method to tackle low efficiency in binocular matching and solving, we successfully performed swift and synchronized measurements for a large batch of specular surfaces and obtained the three-dimensional surface profile of each measured surface. Through experimental validation, the method proposed in this paper can perform the batch measurement of specular planes while maintaining high measurement accuracy.
The Uncertainty Assessment by the Monte Carlo Analysis of NDVI Measurements Based on Multispectral UAV Imagery
Authors: Khalesi Fatemeh , Ahmed Imran , Daponte Pasquale , Picariello Francesco , De Vito Luca , Tudosa Ioan
Published: April 2024

This paper proposes a workflow to assess the uncertainty of the Normalized Difference Vegetation Index (NDVI), a critical index used in precision agriculture to determine plant health. From a metrological perspective, it is crucial to evaluate the quality of vegetation indices, which are usually obtained by processing multispectral images for measuring vegetation, soil, and environmental parameters. For this reason, it is important to assess how the NVDI measurement is affected by the camera characteristics, light environmental conditions, as well as atmospheric and seasonal/weather conditions. The proposed study investigates the impact of atmospheric conditions on solar irradiation and vegetation reflection captured by a multispectral UAV camera in the red and near-infrared bands and the variation of the nominal wavelengths of the camera in these bands. Specifically, the study examines the influence of atmospheric conditions in three scenarios: dry–clear, humid–hazy, and a combination of both. Furthermore, this investigation takes into account solar irradiance variability and the signal-to-noise ratio (SNR) of the camera. Through Monte Carlo simulations, a sensitivity analysis is carried out against each of the above-mentioned uncertainty sources and their combination. The obtained results demonstrate that the main contributors to the NVDI uncertainty are the atmospheric conditions, the nominal wavelength tolerance of the camera, and the variability of the NDVI values within the considered leaf conditions (dry and fresh).