bluuebunny/crossref_metadata_2025 huggingface dataset:
STRATEGI MENINGKATKAN VOLUME PENJUALAN KRIPIK TEMPE DI MASA PANDEMI PADA HOME INDUSTRY SUMBER AGUNG, PETORAN, JEBRES, SURAKARTA
Authors: Desma Rahadhini Marjam , Lamidi Lamidi
Published: February 2022

Kegiatan pengabdian kepada masyarakat ini, mengambil obyek home industry Sumber Agung di Petoran, Jebres, Surakarta. Tujuan dilakukan pengabdian untuk memberikan pelatihan dan penyuluhan kepada pengelola home industry Sumber Agung agar mampu beradaptasi terhadap perubahan tehnologi informasi, dalam upaya mengelola dan mengembangkan usahanya, serta membantu memberikan solusi untuk mengatasi permasalahan yang dihadapi, khususnya pada aspek pemasaran produk.Beberapa permasalahan yang dihadapi, antara lain: 1) pada masa pandemi covid 19 penjualan kripik tempe mengalami penurunan yang sangat signifikan, sekitar 50%. 2) proses pengirisan tempe hanya dilakukan secara manual, padahal dalam kondisi normal dapat menghabiskan bahan baku kedelai 70 kg/hari, akibatnya tidak efisien dalam produksi, 3) pemilik belum memahami makna pentingnya branding dan packing. Metode pelaksanaan pengabdian ini dengan melakukan pendampingan dalam bentuk pelatihan dan penyuluhan pada home industry Sumber Agung. Secara tehnis dengan mengadakan pelatihan penggunaan media sosial (whatsapp, facebook dan instagram) dan penyuluhan tentang pentingnya memahami branding dan packing. Hasil dari kegiatan pendampingan ini, facebook yang digunakan ”Kripik Sumber Agung” dan instagram yang digunakan “Sumberagungsolo”. Luaran dari kegiatan pengabdian ini, artikel pengabdian yang dimuat di Jurnal Pengabdian Terakreditasi Nasional.

 Kata kunci: kripik tempe, pendampingan, sosial media
Szállodai létesítmények robbantások elleni védelmének lehetőségei
Authors: Lukács László , Balogh Zsuzsanna
Published: February 2022

A terrorista-támadások során az elkövetők célja a lehető legnagyobb pusztítás mellett, hogy tettük minél szélesebb körű publicitást kapjon. Ehhez az egyik széleskörűen alkalmazott eszköz a robbanóanyag, amelyet akár rejtetten, akár erőszakos úton, például tehergépjárművel áttörve juttatnak el a tervezett célponthoz, célpontba. A támadások olyan helyszínekre irányulnak, ahol sokan, sok helyről érkezve tartózkodnak egy helyen. Az elmúlt évek eseményei bizonyítják, hogy a kedvelt turistacélpontok szállodai létesítményeiben is történtek ilyen merényletek. A tanulmányban e létesítmények védelmi szintjének, fizikai biztonságtechnikai eszközökkel történő fokozásának lehetőségeit foglaljuk össze bizonyítva, hogy a külső esztétikum és a magas hatásfokú védelem ma már kölcsönösen biztosítható.
Zömítő tompahegesztéssel toldott betonacél szálak alkalmazhatóságának vizsgálata
Authors: Harangozó Dóra , Harrach Dániel
Published: February 2022

Rendeltetés, szerkezet, anyaghasználat és mobilitás szerint különféle létesítmények állnak a hadiipar szolgálatában. Jelen cikk a betonacél-erősítésű konstrukciókkal foglalkozik, amelyek például hidak, csarnokok, védő és kiszolgáló épületek szerkezetében fordulnak elő. Mivel a betonacél szálak hosszúsága gyártásilag – különösképp a nagyobb átmérőjűek esetében – korlátozott, illetve a gazdaságos felhasználás érdekében sok esetben szükséges az egyes szálak toldása, aminek lehetőségeit európai szabványok szabályozzák. Jelen kutatás célja a hazai viszonylatban még nem alkalmazott betonacél toldási módjának alkalmazási kockázatértékelése és az esetleges teherbírás-csökkenés okainak feltárása laboratóriumi vizsgálatokkal. Zömítő tompahegesztéssel toldott betonacél szálak keresztirányú szakítóvizsgálatát, illetve átfogó anyagvizsgálatát végeztük el a kötéstípus pontos tulajdonságainak meghatározása érdekében. Megállapítottuk, hogy a hegesztett szálak egytengelyű húzó igénybevétellel szembeni ellenállása átlagosan körülbelül 80%-aaz alapanyagénak, illetve a hajlított tartó teherbírását is nagyjából ilyen mértékben befolyásolja a toldott szálak alkalmazása. A hagyományos metallográfiai vizsgálatok eredményei megfelelnek a vonatkozó szabványok előírásainak, így a vizsgált technológia a kockázati tényezők körültekintő figyelembevételével alkalmazható az említett szerkezetekben.
Szivárgáshidraulikai vizsgálatok a Kolon-tó vízgyűjtőjén
Authors: Koch Dániel , Kutassy Emese , Nagy Tamás
Published: February 2022

A Duna–Tisza közi homokhátságon időről időre vízgazdálkodási problémák jelennek meg. Ezek elsődleges kiváltó oka a részben antropogén hatásnak, részben pedig természeti folyamatoknak köszönhető talajvízszint-süllyedés. A talajvízszint-süllyedés a vizes élőhelyeken, mezőgazdasági és erdőgazdasági területeken egyaránt gondot okoz, és konfliktusokhoz vezet a tavak üzemeltetési kérdéseiben. Ezek a negatív hatások érintik a Kolon-tavat is, amely a Kiskunság kiemelt jelentőségű édesvízi mocsara. A Kolon-tó térségében jelentkező vízhiány távlatilag öntözési szükségleteket támaszthat a tó vízgyűjtőjén. Az ilyen irányú hatásokat próbáljuk előre jelezni a vízgyűjtőjére készített hidrodinamikai modell segítségével. A tárgyi modellvizsgálatok célja annak feltárása, milyen várható hatást gyakorol ezen a területen a vízszintpotenciál-eloszlásra, ha azzal számolunk, hogy a talajvízkészletet érintő rendszeres öntözési vízkivételre kerül majd ott sor.
Biden Cancels Keystone XL: How Alberta’s Local Media Is Framing the News
Authors: Mastantuono Samantha
Published: February 2022

Climate change mitigation is frequently presented as a binary trade-off between economic development and environmental protection, particularly in Canadian news. The economic value and “necessity” of the oil sands is often used as a justification for perpetual extractivism and further expansion of energy infrastructure. News media have an important role in delivering information and shaping public opinion on large-scale issues in society, including the issue of climate change.

This Major Research Paper explores Alberta’s local news media’s reaction to the cancellation of the Keystone XL pipeline by examining the narratives used in their reporting of the news. I highlight the importance of studying Canadian local news influence on public perception of issues, as this is often not adequately represented in environmental communications research. I conducted an exploratory content analysis of articles from three local news publications, the Calgary Herald, the Red Deer Advocate, and the Lethbridge Herald. The findings suggest economic arguments that justify oil sands expansion largely overshadow pro-environment representation of the issue. This study also uncovers high use of victim narratives that perpetuate extractivism by using “us versus them” populist rhetoric in storylines.
Search-and-Rescue Algorithm: Detecting Access Holes in Disaster Rubble
Authors: Kong Christopher
Published: February 2022

[Para. 1 of Summary]

Soon after our species began constructing buildings thousands of years ago we also had to start dealing with our
homes and other buildings collapsing – whether the result of natural forces such as earthquakes or typhoons, or the
effect of human causes such as sabotage, warfare or just plain shoddy workmanship. A grave consequence of
structural collapse is the fact that people often find themselves trapped and injured within rubble, all too often dying
before they can be found and extricated.
DE NUESTRA IDENTIDAD COMO MUJERES VIEJAS: Cuerpo, sexualidad y resiliencia
Authors: Meza Márquez Consuelo
Published: February 2022

El libro Reinvención de nuestra identidad como mujeres viejas. Cuerpo, sexualidad y resiliencia muestra los signos y los juicios de la edad en la narrativa cultural, una en la que se encuentran entretejidos los elementos simbólicos que nos construyen como cuidadoras de otros y una concepción de fealdad y desecho de nuestras vejeces. La sexualidad entre los viejos se considera tabú, se niega, no se le nombra e incluso se considera una especie de estigma o perversión. En esta reflexión, acompañadas de nuestras hermanas/pares, la resiliencia es la capacidad para superar nuestra condición de otredad, de diferencia frente a esa mística de la juventud y reinventarnos como mujeres que hemos recuperado el gozo de ser mujeres viejas, sujetas de deseos eróticos y protagónicos.
LECTURAS DIVERSAS SOBRE LA PRENSA EN MÉXICO, SIGLOS XIX Y XX
Authors: Solís Hernández Oliva , Ramírez Hurtado Luciano , Jaime Espinosa María Elizabeth
Published: February 2022

Lecturas diversas sobre la prensa en México, siglos XIX y XX reúne los esfuerzos de varios investigadores que se han abocado a estudiar los medios impresos periódicos desde distintos ángulos del fenómeno, novedosos abordajes teóricos y aproximaciones metodológicas desde distintas disciplinas de las ciencias sociales. Comprende una docena de textos que agrupan múltiples dimensiones y dan cuenta de cambios sociales e ideológicos fundamentales con una perspectiva histórica, desde estudios de caso de algunas empresas, actores y proyectos periodísticos, hasta llegar a tópicos que revisten una enorme actualidad, como son las voces y representaciones femeninas y feministas en periódicos y revistas, roles de género focalizados en anuncios publicitarios, pasando por espacios de la prensa como escenario de la crítica cinematográfica y la censura teatral, así como la prensa como fuente para reconstruir la vida cotidiana, la atmósfera social y cultural, e incluso momentos clave del desarrollo de instituciones eclesiásticas, además de museísticas. Los límites geográficos se funden en un ir y venir entre la capital del país y ciudades de provincia como Querétaro, Guadalajara y Aguascalientes, transitando por cortes y periodizaciones en el tiempo donde se abarca la restauración de la república, el Porfiriato, la Revolución mexicana y la etapa posrevolucionaria.
VIDAS DE SANGRE: Mujeres en la narrativa mexicana del crimen
Authors: Fourez Cathy
Published: February 2022

Con un corpus de novelas, cuentos y crónicas publicados, en gran parte, entre 2010 y 2016, y cuyos cimientos se trazan desde un México brutal y bárbaro, en Vidas de sangre se tratará de entender cómo son narrados los antecedentes y los efectos de la violencia vigente sobre la vida cotidiana de las mujeres; de estudiar lo que dicen estos textos a propósito de la sociedad mexicana y de las relaciones de género entre los individuos; de observar cómo expresan e interpretan la permanencia y la intensificación de los “modelos” de lo femenino; y también de destacar cómo revelan que la violencia vivida y sus múltiples perfiles perturban, desplazan lo que se esperaría, en la práctica normativa, de lo femenino. Por eso, nos parece atinado identificar, describir y examinar varias representaciones de mujeres en la violencia del México ultracontemporáneo a través de las literaturas policíacas, y más precisamente con el apoyo de una producción que llamaremos “relatos del crimen”, los cuales van de la ficción a la investigación periodística.
The Farmers' Perceptions of Processed Morage Leaf Pudding in Padang Village (Case study in Padang Village, Manggeng District, Aceh Barat Daya Regency)
Authors: Maulidin Maulidin , Dedy Darmansyah
Published: February 2022

Moringa is a plant which has a myriad of benefits, Moringa leaves which have complete nutritional content are very good for daily consumption to meet protein for the body, especially children in their infancy. This research was conducted in the village of Padang, Manggeng District, Southwest Aceh Regency, the purpose of this study was to find out how farmers' perceptions of processed Moringa leaf pudding in the village of Padang. From the research results, it is known that farmers' perceptions of processed Moringa leaves can be categorized as good, from the highest total value of the overall research results obtained a perception value of 92.67%, and the lowest value of 82.67%, this value indicates that farmers' perceptions of processed leaves Moringa is good and can be used for food to meet daily nutritional needs. The conclusion drawn in this study is that Moringa is a plant that contains a lot of nutrients that is easy to process as food and has an attractive color and good taste.
Emergence of non-choleragenic Vibrio infections in Australia
Authors: Harlock Michelle , Quinn Stewart , Turnbull Alison R
Published: February 2022

Vibrio infection was rarely reported in Tasmania prior to 2016, when a multistate outbreak of Vibrio parahaemolyticus associated with Tasmanian oysters was identified and 11 people reported ill. Since then, sporadic foodborne cases have been identified following consumption of commercially- and recreationally-harvested oysters. The increases in both foodborne and non-foodborne Vibrio infections in Tasmania are likely associated with increased sea water temperatures. As oyster production increases and climate change raises the sea surface temperature of our coastline, Tasmania expects to see more vibriosis cases. Vibriosis due to oyster consumption has been reported in other Australian states, but the variability in notification requirements between jurisdictions makes case and outbreak detection difficult and potentially hampers any public health response to prevent further illness.
Allelopathic activity of Azadirachta indica A.Juss. on Handroanthus serratifolius (Vahl) S.Grose
Authors: Nascimento Gabriel Messias da Silva , Leandro Cícero dos Santos , Alcântara Bruno Melo de , Miranda de Oliveira Francisco Alex , Silva Viviane Bezerra da , Bezerra José Weverton Almeida , Lacerda Sírleis Rodrigues , Silva Maria Arlene Pessoa da
Published: February 2022

Allelopathy involves the direct or indirect, stimulating or inhibiting action, promoted by substances called allelochemicals which, when released into the environment, can interfere positively or negatively in the development and germination of surrounding species. The objective of this work was to evaluate the allelopathic potential of Azadirachta indica A.Juss (Meliaceae) leaves on seed germination and seedling development of Handroanthus serratifolius (Vahl) S.Grose (Bignoniaceae). The experimental design used was completely randomized with four treatments and a control group (distilled water). Each treatment consisted of four replicates of 15 seeds each. The aqueous extract was prepared by grinding 250 g of fresh leaves in 1 L of distilled water, where further dilutions were made at concentrations of 25%, 50%, 75% and 100%. Germination rate, germination speed index (IVG), radicle length and stem length were analyzed. In addition to the pH and osmolarity of the extracts. And the phytochemical prospection to determine the main classes of secondary metabolites. Seed germinability was only affected by the extract at 100% concentration. It was also observed a reduction in the length of the stems and radicles of seedlings subjected to extracts at the highest concentrations. The observed effect may be due to the presence of alkaloids, flavonoids and phenolic compounds, since these compounds have proven action on the development of seedlings.
Análise da composição e distribuição da arborização de ruas como ferramenta para o planejamento urbano
Authors: Pinheiro Maiara Aparecida , Costa Danilo Ribeiro da , Dutra Felipe Bueno , Francisco Bruno dos Santos , Teração Bruna Santos , Perussi Gabriel , Viveiros Emerson , Silva José Mauro Santana da
Published: February 2022

O planejamento urbano de um município, quando bem realizado, resulta em aumento da qualidade de vida dos munícipes via diversos fatores, como melhor mobilidade urbana, conforto térmico e até benefícios na saúde. Diante do aumento da urbanização e seu impacto no meio ambiente, bem como a necessidade da criação de políticas públicas, o objetivo do trabalho foi avaliar a situação do planejamento urbano do bairro Jardim Aeroporto do município de Itu, São Paulo, Brasil. Foi realizado o inventário e georreferenciamento dos indivíduos arbóreos de 22 vias. Para análise da distribuição espacial, os dados foram avaliados utilizando-se o índice de Kernel e o índice de grau de atenção. Foram amostrados 338 indivíduos arbóreos distribuídos em 26 famílias e 47 espécies, sendo a espécie Murraya paniculata (L.) Jack, de origem exótica a mais frequente (15,68%) . Apenas uma via apresentou nível de atenção baixo, as demais ficaram entre médio e alto nível de atenção (n=21). Além disso constatou-se um déficit de 1352 árvores no bairro. Os resultados mostram que as vias do bairro Jardim Aeroporto têm distribuição desigual de indivíduos arbóreos com uma quantidade considerável de espécies exóticas utilizadas na arborização regional. A proximidade entre algumas árvores e sua distribuição em áreas de risco na cidade mostram como muitas vezes não há um planejamento urbano de longo prazo, podendo causar riscos à integridade física de imóveis e munícipes quando associados ao manejo inadequado das espécies.
Relação entre o nível de atividade física e seus reflexos na saúde mental e na qualidade de vida da população durante a pandemia de COVID-19
Authors: Leão Marcos , Lavorato Victor Neiva , Oliveira Renata Aparecida Rodrigues de , Rosado Daniela Gomes , Jardim Isabela Alcântara Barretto Araújo , Isoldi Mauro Cesar , Miranda Denise Coutinho de
Published: February 2022

A diminuição dos níveis de atividade física, o aumento do estresse e a queda no convívio social estão diretamente relacionadas à redução da qualidade de vida. O objetivo do presente estudo foi verificar se o nível de atividade física afeta a qualidade de vida de adultos durante a pandemia da Covid-19. Foi realizado um estudo descritivo em indivíduos de ambos os gêneros, sendo aplicados três questionários, um que avalia o nível de atividade física (IPAQ), o outro que analisa a percepção subjetiva da qualidade de vida (WHOQOL) e um terceiro, que avalia a percepção do efeito da pandemia na qualidade de vida. Foi visto que 46,16% dos participantes eram pouco ativos; aproximadamente 65% relataram piora na saúde mental e na qualidade de vida, sendo observadas alterações nos domínios físico, ambiental e social. Não foi possível relacionar a prática de atividade física com altos índices de qualidade de vida, mas observa-se que a pandemia influenciou negativamente a saúde mental e a qualidade de vida da população. Fazem-se necessários novos estudos e novas análises para melhor compreender essa relação entre a qualidade de vida e a atividade física em um cenário de pandemia.
Residual da adubação fosfatada e efeito da inoculação com Azospirillum brasilense em milho verão consorciado com gramínea em região de cerrado
Authors: Dickmann Lourdes , Nakao Allan Hisashi , Modesto Viviane Cristina , Sanches Izabela Rodrigues , Andreotti Marcelo
Published: February 2022

A crescente necessidade de ter sistemas de produção agrícolas sustentáveis, faz com que o agronegócio busque estratégias para atender o aumento da demanda por matérias-primas animais e vegetais, impulsionando o maior uso da terra. O trabalho teve como objetivoavaliar o efeito residual da adubação fosfatada sobre o crescimento e produtividade do milho com e sem inoculação de A. brasilense e da produção de massa seca do capim-marandu em consórcio. O experimento foi desenvolvido em área exprimental pertencente à FE/UNESP, em Selvíria, MS. O solo foi classificado como Latossolo Vermelho distrófico típico argiloso. Os experimentos de consórcio de milho com U. brizantha cv. Marandu (capim-marandu) foram desenvolvidos nas safras de 2013/14 e 2015/16. O delineamento experimental foi o de blocos casualizados, com quatro repetições, em esquema fatorial 5 x 2. Avaliou-se o efeito residual de níveis de adubação fosfatada (0; 30; 60; 120 e 240 kg ha-1 de P2O5), aplicados a lanço na semeadura da aveia preta em junho de 2013, com ou sem a inoculação das sementes de milho com A. brasilense. De acordo com os resultados obtidos, a inoculação das sementes de milho por A. brasilense e a adubação fosfatada residual não resultaram em efeitos positivos sobre o crescimento, componentes da produção e produtividade de grãos de milho consorciado com capim-marandu. Por sua vez, o capim-marandu foi beneficiado pela inoculação, nas sementes de milho, produzindo maior massa de parte aérea em áreas inoculadas com A. brasilense.
Effect of a diamond-like carbon film on the mechanical and surface properties of microwave-cured polymethylmethacrylate
Authors: Silva Pâmela Lopes Pedro da , Lemos George Azevedo , Sousa Frederico Barbosa de , Sobrinho Argemiro Soares da Silva , Queiroz José Renato Cavalcanti de , Batista André Ulisses Dantas
Published: February 2022

Introduction: Microwave-cured polymethylmethacrylate (MCPM) are commonly used in dentistry due low cost, transparency and easy handling. However, do not have a long useful life, due to their chemical fragility and low hardness and wear resistance. Aim: Assessing the effect of a diamond-like carbon (DLC) film coating on the mechanical and surface properties of MCPM. Methodology: The MCPM samples were divided into control (Gc) and treatment (Gt) groups, and were subjected to flexural strength (n=18), wear resistance (n=18) tests, and to topography and surface roughness (Ra) analysis by three-dimensional optical profilometry (n=18). The films were deposited by plasma-enhanced chemical vapor deposition. Differences between groups were assessed by the Mann-Whitney and t tests using a 5% significance level (p<0.05). Results: The Gt had higher surface roughness (0.108 ± 0.01µm) than the Gc (0.038 ± 0.01µm), with p<0.0001. No significant difference (p=0.606) in flexural strength was found between Gt (103.3 MPa) and Gc (105.3 MPa). No significant difference was found between the groups in terms of straightness (Gt: 0.006 ± 0.0059 mm and Gc 0.005 ± 0.0052mm, p=0.774) or indentation depth (Gt: 29.974 ± 8.69µm and Gc: 28.169 ± 5.71µm, p=0.610) after the wear test. Conclusion: Coating the MCPM surface with a DLC film affected the surface roughness, with no effects on flexural strength and wear resistance. New studies are suggested to better understand these effects, perhaps with variations in the deposition parameters such as coating thickness or on the sp3/sp2 ratio.
Functional Foods as the Prospective Therapeutic Option in Chronic Diseases. A Systemic Review
Authors: Nazir Anum , Itrat Nizwa , Saleem Muhammad Awais , Nisa Mahr Un , Shahid Aleena , Mushtaq Zain , Rafey Hafiz Abdul
Published: February 2022

Chronic diseases become the leading cause of more than 50% of deaths around the world. The real reason is inflammation behind all chronic diseases like chronic kidney disease, ischemic heart disease, diabetes, and hypertension. There are several functional foods which involve in the management and treatment of many diseases because they provide nutrition and potential health benefits. Bioactive compounds in functional foods are responsible for all these health benefits present in them. The nutritional, physiological, and immunological properties of Nutraceutical foods promise health-promoting as well as disease-preventing potential. Natural food commodities such as whole-grain cereals, fruits and vegetables, nuts, healthy fats, low-fat dairy products, and some other nutraceutical compounds such as herbs and spices provide health benefits by promoting wellness, protecting against the diseases and their complications, slowing, or omitting the disease progression, promote healthy gut health, prevent from deficiencies, and help in to sustain the healthy lifestyle. The purpose of this systemic review was to describe the effects and outline some promising potentials of functional foods against disease prevention and treatment.
PENGARUH PERILAKU KEPEMIMPINAN, KOMPETENSI PROFESIONAL DAN LINGKUNGAN KERJA NON FISIK TERHADAP KINERJA GURU (Studi Pada SMA Se-Kecamatan Batalaiworu Kabupaten Muna)
Authors: Sarpan Wa Ode , Hatani La , Suleman Nursaban Rommy
Published: February 2022

The purpose of this research is to test and explain the influence of leadership behavior, professional competence and non-physical work environment on teacher performance. This research approach is quantitative with a positivist paradigm. Data was collected by cross-section by using a questionnaire. The population of this study were all 141 teachers at SMA in Batalaiworu District, Muna Regency. The sample size was determined using a purposive sampling technique, namely teachers who were civil servants (PNS), so that a sample of 118 people was obtained. The analytical tool used is Multivariate Regression Analysis. The results showed that leadership behavior, professional competence and non-physical work environment simultaneously had a positive and significant effect on teacher performance. Then leadership behavior partially positive and significant effect on teacher performance. Professional competence partially has a positive and significant effect on teacher performance. and the non-physical work environment has a positive and significant effect on teacher performance. This means that the more leadership behavior, professional competence and non-physical work environment increase, the teacher's performance will increase significantly.
PERAN KEPUASAN KERJA DALAM MEMEDIASI PENGARUH LINGKUNGAN KERJA, GAYA KEPEMIMPINAN DAN BUDAYA ORGANISASI TERHADAP KINERJA PEGAWAI: Studi Kasus di Badan Pendapatan Daerah Kabupaten Muna
Authors: Harmin Harmin , Samdin Samdin , Sukotjo Endro , Hakim Adnan , Masri Muhammad
Published: February 2022

This study aims to explain and examine the effect of the work environment, leadership style, organizational culture on job satisfaction and employee performance, job satisfaction on employee performance, then examine and explain the role of job satisfaction in mediating the influence work environment, leadership style, and organizational culture on employee performance. This research approach is survey with explanatory research design. The data was collected in a cross-sectional manner using an instrument in the form of a questionnaire. The population in this study were all 49 Civil Servants (PNS). The sampling technique is a saturated sample (census) where the entire population is used as the research sample. The data analysis technique to answer the research hypothesis is Partial Least Square (PLS).The results showed that the work environment had a significant effect on job satisfaction, but the work environment had no effect on employee performance, leadership style had a significant effect on job satisfaction and employee performance, organizational culture had a significant effect on job satisfaction and employee performance. Then job satisfaction had a significant effect on employee performance. In addition, the results of this study indicate that job satisfaction acts as a complete mediation the influence of the work environment on employee performance. Then job satisfaction does not mediate (no mediation) the influence of leadership style on employee performance. Furthermore, job satisfaction acts as a partial mediation the influence of organizational culture on employee performance.
The Kanerva Model for Sparse Distributed Memory and the Architecture of the Cerebellum
Authors: Prager Richard
Published: February 2022

It is interesting to compare the connectivity in Kanerva’s sparse distributed memory model with the connectivity in the cerebellum.
Seeing Images
Authors: Petersson Sonya , Dahlgren Anna
Published: February 2022

In the cultural heritage digital archive, descriptive metadata makes images (re)searchable. Text-based searches seek terms that match metadata terms or terms referring to aspects of images that have previously been considered essential to select and describe in metadata terms. Such considerations are bound up with historically changing institutional agendas, ideas about user preferences, and implementation of metadata standards. This study approaches image accessibility from a different perspective. It aims to investigate how the infrastructure of the digital archive, comprising metadata and interface, intervenes with, circumscribes as well as enables, the images’ visibility and knowledge-producing capacity. The starting points are: first, that images in digital archives, exemplified by the online image collections in Alvin and DigitaltMuseum, are mediated, mediating, and “mixed” media objects that simultaneously represent the past and the present; second, that the digital archive in a media history of images functions as both a tool and an object of research. Using the platforms as tools of research, this study is based on test searches that aim to find viable search strategies for mixed media objects. The chosen search terms represent media-historically significant and common traits such as images that are combined with text and images that represent and/or mediate other images. The study discloses that the platforms give both false negatives and false positives. They do not support searches that focus media terms and relations between media elements. These problems are further related both to heterogenous metadata practices and to the simultaneously restricted and broad image concept behind them. As objects of research, both platforms are considered in relation to a future construction of a media history of images, where the digital archive is a particular node. The study demonstrates how the “hypermedial” environment associated with new media is prefigured by media interrelations in analog images – or images that are accessible as mediated through the archive’s interface and as policed by the archive’s metadata structure.
Decellularized Tissues for Wound Healing: Towards Closing the Gap Between Scaffold Design and Effective Extracellular Matrix Remodeling
Authors: Solarte David Víctor Alfonso , Güiza-Argüello Viviana Raquel , Arango-Rodríguez Martha L. , Sossa Claudia L. , Becerra-Bayona Silvia M.
Published: February 2022

The absence or damage of a tissue is the main cause of most acute or chronic diseases and are one of the appealing challenges that novel therapeutic alternatives have, in order to recover lost functions through tissue regeneration. Chronic cutaneous lesions are the most frequent cause of wounds, being a massive area of regenerative medicine and tissue engineering to have efforts to develop new bioactive medical products that not only allow an appropriate and rapid healing, but also avoid severe complications such as bacterial infections. In tissue repair and regeneration processes, there are several overlapping stages that involve the synergy of cells, the extracellular matrix (ECM) and biomolecules, which coordinate processes of ECM remodeling as well as cell proliferation and differentiation. Although these three components play a crucial role in the wound healing process, the ECM has the function of acting as a biological platform to permit the correct interaction between them. In particular, ECM is a mixture of crosslinked proteins that contain bioactive domains that cells recognize in order to promote migration, proliferation and differentiation. Currently, tissue engineering has employed several synthetic polymers to design bioactive scaffolds to mimic the native ECM, by combining biopolymers with growth factors including collagen and fibrinogen. Among these, decellularized tissues have been proposed as an alternative for reconstructing cutaneous lesions since they maintain the complex protein conformation, providing the required functional domains for cell differentiation. In this review, we present an in-depth discussion of different natural matrixes recently employed for designing novel therapeutic alternatives for treating cutaneous injuries, and overview some future perspectives in this area.
The Roles of Noncoding RNAs in the Development of Osteosarcoma Stem Cells and Potential Therapeutic Targets
Authors: Liu Jinxin , Shang Guanning
Published: February 2022

Osteosarcoma (OS) is the common bone tumor in children and adolescents. Because of chemotherapy resistance, the OS patients have a poor prognosis. The one reason of chemotherapeutic resistance is the development of cancer stem cells (CSCs). CSCs represent a small portion of tumor cells with the capacity of self-renewal and multipotency, which are associated with tumor initiation, metastasis, recurrence and drug resistance. Recently, noncoding RNAs (ncRNAs) have been reported to critically regulate CSCs. Therefore, in this review article, we described the role of ncRNAs, especially miRNAs, lncRNAs and circRNAs, in regulating CSCs development and potential mechanisms. Specifically, we discussed the role of multiple miRNAs in targeting CSCs, including miR-26a, miR-29b, miR-34a, miR-133a, miR-143, miR-335, miR-382, miR-499a, miR-1247, and let-7days. Moreover, we highlighted the functions of lncRNAs in regulating CSCs in OS, such as B4GALT1-AS1, DANCR, DLX6-AS1, FER1L4, HIF2PUT, LINK-A, MALAT1, SOX2-OT, and THOR. Due to the critical roles of ncRNAs in regulation of OS CSCs, targeting ncRNAs might be a novel strategy for eliminating CSCs for OS therapy.
Online Internal Temperature Sensors in Lithium-Ion Batteries: State-of-the-Art and Future Trends
Authors: Jinasena Asanthi , Spitthoff Lena , Wahl Markus Solberg , Lamb Jacob Joseph , Shearing Paul R. , Strømman Anders Hammer , Burheim Odne Stokke
Published: February 2022

The temperature of the lithium-ion battery is a crucial measurement during usage for better operation, safety and health of the battery. In-situ monitoring of the internal temperature of the cells is an important input for temperature control of battery management systems and various other related measurements of the battery, such as state-of-charge and state-of-health. Currently, most commercial battery management systems rely on the surface temperature measurements of the cell. However, the internal temperature is comparatively higher than the surface temperature due to heat generation within the cell and lower heat rejection compared to the surface; therefore, accurate internal temperature monitoring methods are essential to improve our knowledge of battery safety and health. This paper reviews the most recent studies of various online internal temperature monitoring techniques under two main themes of hard sensors and soft sensors. The hard sensors include sensors that need to be inserted into the cell and other methods that use contact-less measuring techniques to infer the internal temperature. The soft sensors include estimators/observers that use surface measurements and various models to estimate the internal temperature. More focus is given to the soft sensors due to the lack of an existing, in-depth review of these. These methods are analyzed in detail with their accuracy, implementation, measurement frequency, and the common challenges and benefits are discussed. Further, possible future trends in internal temperature sensing are also discussed.
A Portable Molecularly Imprinted Sensor for On-Site and Wireless Environmental Bisphenol A Monitoring
Authors: Beduk Tutku , Gomes Matilde , De Oliveira Filho José Ilton , Shetty Saptami Suresh , Khushaim Walaa , Garcia-Ramirez Ricardo , Durmus Ceren , Ait Lahcen Abdellatif , Salama Khaled Nabil
Published: February 2022

The detection of pollutant traces in the public and environmental waters is essential for safety of the population. Bisphenol A (BPA) is a toxic chemical widely used for the production of food storage containers by plastic industries to increase the storage ability. However, the insertion of BPA in water medium leads to serious health risks. Therefore, the development of low-cost, practical, sensitive, and selective devices to monitor BPA levels on-site in the environment is highly needed. Herein, for the first time, we present a homemade portable potentiostat device integrated to a laser-scribed graphene (LSG) sensor for BPA detection as a practical environmental pollutant monitoring tool. Recently, there has been an increasing need regarding the development of graphene-based electrochemical transducers (e.g., electrodes) to obtain efficient biosensing platforms. LSG platform is combined with molecularly imprinted polymer (MIP) matrix. LSG electrodes were modified with gold nanostructures and PEDOT polymer electrodeposition to create a specific MIP biomimetic receptor for ultrasensitive BPA detection. The sensing device has a Bluetooth connection, wirelessly connected to a smartphone providing high sensitivity and sensitivity (LOD: 3.97 nM in a linear range of .01–10 µM) toward BPA. Two commercial bottled water samples, tap water, commercial milk, and baby formula samples have been used to validate the reliability of the portable sensor device.
Genomic Characteristics and Pan-Genome Analysis of Rhodococcus equi
Authors: Song Yang , Xu Xinmin , Huang Zhenzhou , Xiao Yue , Yu Keyi , Jiang Mengnan , Yin Shangqi , Zheng Mei , Meng Huan , Han Ying , Wang Yajie , Wang Duochun , Wei Qiang
Published: February 2022

Rhodococcus equi is a zoonotic pathogen that can cause fatal disease in patients who are immunocompromised. At present, the epidemiology and pathogenic mechanisms of R. equi infection are not clear. This study characterized the genomes of 53 R. equi strains from different sources. Pan-genome analysis showed that all R. equi strains contained 11481 pan genes, including 3690 core genes and 602 ~ 1079 accessory genes. Functional annotation of pan genome focused on the genes related to basic lifestyle, such as the storage and expression of metabolic and genetic information. Phylogenetic analysis based on pan-genome showed that the R. equi strains were clustered into six clades, which was not directly related to the isolation location and host source. Also, a total of 84 virulence genes were predicted in 53 R. equi strains. These virulence factors can be divided into 20 categories related to substance metabolism, secreted protein and immune escape. Meanwhile, six antibiotic resistance genes (RbpA, tetA (33), erm (46), sul1, qacEdelta 1 and aadA9) were detected, and all strains carried RbpA related to rifamycin resistance. In addition, 28 plasmids were found in the 53 R. equi strains, belonging to Type-A (n = 14), Type-B (n = 8) and Type-N (n = 6), respectively. The genetic structures of the same type of plasmid were highly similar. In conclusion, R. equi strains show different genomic characteristics, virulence-related genes, potential drug resistance and virulence plasmid structures, which may be conducive to the evolution of its pathogenesis.
Dissecting the Polygenic Basis of Primary Hypertension: Identification of Key Pathway-Specific Components
Authors: Maj Carlo , Salvi Erika , Citterio Lorena , Borisov Oleg , Simonini Marco , Glorioso Valeria , Barlassina Cristina , Glorioso Nicola , Thijs Lutgarde , Kuznetsova Tatiana , Cappuccio Francesco P. , Zhang Zhen-Yu , Staessen Jan A. , Cusi Daniele , Lanzani Chiara , Manunta Paolo
Published: February 2022

Introduction and Objectives

Genome-wide association studies have identified a high number of genetic loci associated with hypertension suggesting the presence of an underlying polygenic architecture. In this study, we aimed to dissect the polygenic component of primary hypertension searching also for pathway-specific components.

Methods

The polygenic risk score (PRS) models, based on the UK biobank genetic signals for hypertension status, were obtained on a target Italian case/control cohort including 561 cases and 731 hyper-normal controls from HYPERGENES, and were then applied to an independent validation cohort composed by multi-countries European-based samples including 1,284 cases and 960 hyper-normal controls.

Results

The resulting genome-wide PRS was capable of stratifying the individuals for hypertension risk by comparing between individuals in the last PRS decile and the median decile: we observed an odds ratio (OR) of 3.62, CI = [2.01, 6.32] (P = 9.01E-07) and 3.22, 95% CI = [2.06, 5.10] (P = 6.47E-08) in the target and validation cohorts, respectively. The relatively high case/control ORs across PRS quantiles corroborates the presence of strong polygenic components which could be driven by an enrichment of risk alleles within the cases but also by potential enrichment of protective alleles in the old normotensive controls. Moreover, novel pathway-specific PRS revealed an enrichment of the polygenic signal attributable to specific biological pathways. Among those the most significantly associated with hypertension status was the calcium signaling pathway together with other mainly related such as the phosphatidylinositol/inositol phosphate pathways.

Conclusions

The development of pathway-specific PRS could prioritize biological mechanisms, according to their contribution to the genetic susceptibility, whose regulations might be a potential pharmacological preventive target.
An Upper Paleolithic Perforated Red Deer Canine With Geometric Engravings From QG10, Ningxia, Northwest China
Authors: Zhang Yue , Doyon Luc , Peng Fei , Wang Huimin , Guo Jialong , Gao Xing , Zhang Shuangquan
Published: February 2022

Personal ornaments are key archaeological remains to investigate prehistoric symbolic systems, and, whenever hard animal remains were used for their manufacture, explore topics on the status attributed to faunal resources by past human groups. Since the onset of the Upper Paleolithic, animal tooth pendants have been widely used in Eurasia as personal adornments or grave goods. However, only two Late Paleolithic Chinese sites have yielded such adornment types until today, i.e., Zhoukoudian Upper Cave, near Beijing, and Xiaogushan, in the Liaoning Province. Here, we present results from the multidisciplinary analysis of a perforated animal tooth from QG10, a multi-stratified archaeological site located on the Ordos Plateau between the arid and sub-arid belts of Northwest China. Although only partially preserved, zooarchaeological analysis indicates the tooth is a right upper canine of a female red deer (Cervus elaphus). Scraping marks on the labial aspect suggest the tooth was extracted from the animal maxillary shortly after its death. Technological analysis of the perforation confirms it was made by rotation with the help of a lithic point hafted onto a drill. The root and occlusal aspect of the tooth were further modified with five sets of notches and incisions, including four incisions making a hashtag pattern on the occlusal aspect. Technological and morphometric analyses indicate these sets were made by two, perhaps three, individual, i.e., one left-handed and one, perhaps two right-handed, with different tools and techniques. Use wear analysis suggests that the adornment was affixed to the body with the tooth crown facing upward. Finally, chemical characterization of red and black residues still adhering to the root indicates that hematite and charcoal may have been used in the production of an adhesive that would have helped stabilize the personal ornament on the body. Collectively, our results and interpretations shed a new light on the complexity of Late Glacial symbolic system carried by populations living in Northern China. We argue this perforated red deer tooth was introduced in the site following a number of social exchanges over long distance and a long period of time rather than producedin situ.
Evaluation of the Rock Uplift Pattern in the Central Yunnan Subblock, SE Tibetan Plateau: Based on the Bedrock Channel Profile
Authors: Yu Liang , Dong Youpu , Zhou Weiwei , Zhang Dongyue , Wang Dan , Yu Huayu , Ren Yangyang , Li Jiangtao
Published: February 2022

The uplift pattern of the southeastern Tibetan Plateau is strongly related to the topographic evolution stemming from the India–Eurasia collision. However, whether strain is localized along major faults that bound large tectonic blocks or is accommodated across regions has been strongly debated. In this study, we used stream power incision models to obtain the distribution pattern of the channel steepness indices to understand the rock uplift pattern across the area, as increased channel steepness indices often correlate with the rock uplift rates. In this study, the river longitudinal profiles were analyzed to obtain the distribution of the channel steepness indices in the Central Yunnan subblock. The results suggested very weak correlations between the steepness indices and the lithology, precipitation, sediment flux, or channel concavity indices. Along the Xiaojiang strike–slip fault and the interior subblock, the uplift rate was slower, while the northern part had uplifted faster and was controlled by thrust fault systems. The channel steepness increased gradually from south to north. Thus, the distribution pattern of the normalized channel steepness, ksn, index within the Central Yunnan subblock provides notable support for the argument for the thrusting transformation-limited extrusion model of the Tibetan Plateau.
The Seismic Early Warning System of Mexico (SASMEX): A Retrospective View and Future Challenges
Authors: Suárez Gerardo
Published: February 2022

The earthquake early warning system of Mexico, SASMEX, has 30 years of uninterrupted and successful operation. During this time, the system recorded ∼9,800 earthquakes and broadcast 111 alerts. Alerting was simplified recently, avoiding the emission of two types of alerts. Only earthquakes above a magnitude threshold, dependent on distance to the target city are alerted. SASMEX disseminates early warnings using dedicated receivers, public loudspeakers, multi-hazard radios, and participating TV and radio stations. It is estimated that ∼25 million people receive alert messages from SASMEX. Cell-broadcasting messaging, necessary for the timely delivery of alerts, is not implemented by the local cellular phone operators. The addition of cell phone communication would increase the number of users benefitting from the system. SASMEX does not publish ground motion predictions at the time of issuing the alert.Instead, it distributes a map of peak ground acceleration in Mexico City ∼1 minute after the arrival of strong motion, via electronic messaging. The accepted practice for the population in general is to evacuate at the sound of the alert. This is useful in schools and low-rise buildings, where people are generally drilled to evacuate rapidly. It is not effective in high-rise buildings and where large numbers of people concentrate. Finding protection and not trying to evacuate may be a better option, as it is recommended by other seismic early warning systems. The damaging 19 September 2017 earthquake underlined the difficulties of alerting earthquakes at close distances. Using a different sound of the alert or a countdown may be advisable, so people understand they have less time than normally assumed. There are few social studies on the use of the alert. It is suggested to conduct these studies to explore better ways to use and communicate the seismic alert, including automatic processes to shut down hazardous facilities.