bluuebunny/crossref_metadata_2025 huggingface dataset:
A suscetibilidade à erosão como foco de análise: o caso da Bacia Hidrográfica do Ribeirão Paraíso, Caiapônia-GO
Authors: Samay Ribeiro Tavares Kássio , Salazar Vieira Alves Isabelle , De Oliveira Mendes Samuel
Published: September 2024

Este estudo objetivou mapear e comparar a suscetibilidade à erosão na bacia hidrográfica do Ribeirão Paraíso, aplicando a metodologia de Crepani et al. (2001) e confrontando-a com os dados da Embrapa (2020). Utilizando álgebra de mapas para integrar variáveis físico-naturais, identificou-se que a suscetibilidade varia de áreas estáveis a moderadamente suscetíveis, com destaque para a predominância de condições medianamente estáveis/suscetíveis. A comparação dos métodos revelou diferenças significativas nos resultados, enfatizando a utilidade de abordagens complementares para uma avaliação mais abrangente. O estudo realça a relevância de estratégias integradas de planejamento e gestão territorial, evidenciando a análise de suscetibilidade como ferramenta indispensável no mapeamento de riscos, essencial para informar a tomada de decisões na conservação e uso sustentável dos recursos naturais.
Análise SWOT para ordenamento territorial no município de Prata do Piauí (PI), Brasil
Authors: Oliveira Araújo Juliana , De Araujo Sousa Francisco Wellington , Moura Ramos José Germano , De Moura Fé Lima Iracilde Maria
Published: September 2024

Para ampliar o conhecimento sobre o município de Prata do Piauí, na perspectiva geográfica, este trabalho tem como objetivo utilizar a análise SWOT, enquanto ferramenta de avaliação desse município, no intuito de inferir suas peculiaridades, a partir da identificação de suas potencialidades traduzidas em “forças e oportunidades”, enquanto suas dificuldades foram consideradas “fraquezas e ameaças”. Como procedimentos metodológicos utilizou-se o método dedutivo; as pesquisas básica, exploratória e qualitativa e a análise SWOT, com apoio de observações de campo e de técnicas de geoprocessamento. Constatou-se que, apesar da representação negativa que as pessoas exprimem sobre o semiárido e suas fragilidades no âmbito socioeconômico e ambiental, Prata do Piauí apresenta características geográficas de grande potencial para o desenvolvimento da atividade turística, principalmente. Diante das várias revisões nas delimitações do semiárido brasileiro, Prata do Piauí continua pertencendo à sub-região de transição semiárida.
Enfermagem de Saúde Mental Perinatal: Construção de um Programa de Aconselhamento
Authors:   Escola Superior de Saúde de Viseu, Alves Patricia , Sequeira Carlos ,   Escola Superior de Enfermagem do Porto, Néné Manuela ,   Escola Superior de Saúde da Cruz Vermelha Portuguesa de Lisboa, Ribeiro Isilda ,   Escola Superior de Enfermagem do Porto
Published: September 2024

Contexto: O Aconselhamento em Enfermagem é uma Intervenção que reúne um conjunto de conteúdos próprios e uma determinada estrutura, tendo em conta o conhecimento científico. O Enfermeiro Especialista Enfermagem Saúde Mental e Psiquiátrica (EEESMP) presta cuidados de apoio e suporte, permitindo a capacitação das grávidas para lidar com as mudanças emocionais associadas à gravidez. Objetivo: Criar programa de aconselhamento em enfermagem de saúde mental perinatal. Metodologia: Estudo qualitativo, exploratório e descritivo através da scoping review e Focus Group. Resultados: Programa implementado nos cuidados de saúde primários, a iniciar-se a partir das 20 semanas de gravidez. Realizadas sessões individuais presenciais e ou formato híbrido (inicial, final e follow-up) e por sessões de aconselhamento em grupo (máximo oito a 10 participantes) em que foram abordadas as temáticas: Promoção da Saúde Mental Perinatal; Estratégias para o bem-estar; Lidar com o pós-parto. Conclusões: O Programa demostrou a importância da Enfermagem de Saúde Mental Perinatal na promoção da saúde da mulher e o contributo do EEESMP na capacitação, na mudança de comportamento e na literacia neste período tão específico do ciclo vital.
Olympics of emotions - a strategy of promoting mental health with adolescents in the school environment
Authors:   School of the Fluminense Federal University, Tavares Cláudia Mara Melo , Carvalho José Carlos Marques ,   Escola Superior de Enfermagem do Porto, Gomes Aline Dias ,   Fundação Municipal de Saúde, Rebello Marcelle Ignácio ,   School of the Fluminense Federal University, Silva Thiago Nogueira ,   School of the Fluminense Federal University, Tavares Marilei de Melo ,   University of Vassouras, Ribeiro Isilda ,   Escola Superior de Enfermagem do Porto
Published: September 2024

Introduction: Psychological suffering among adolescents and strategies for the promotion of mental health exists and is necessary. Aim: To characterize the emotional demands of school adolescents and describe knowledge about protective factors of mental health. Methods: Sociopoetic research with 30 adolescents. Results/Analysis topics: “Questions of interest about emotions and mental health”; “Dealing with stress and anxiety”; “Reflections on conflict resolution and problems faced”; and “Knowledge about protective factors of mental health”. Conclusions: Recreational and artistic activities are powerful for the promotion of adolescent mental health, and can be implemented through the school-health service partnership.
Uma revisão sistemática da literatura sobre redes semânticas de mapas conceituais
Authors: Grandi Roges , Loiola Alba Valeria de Sant'Anna de Freitas , Wives Leandro Krug , Gomes Raquel Salcedo
Published: September 2024

Introdução: O contexto atual de manipulação de informações preconiza tratamento computacional de dados para geração informacional detalhada e precisa no campo acadêmico. Objetivo: Apresentar uma Revisão Sistemática da Literatura (RSL) apoiada por bibliometria sobre redes semânticas de mapas conceituais (RSMC) – redes de significados nos quais os nodos são conceitos pertencentes a uma coleção de mapas conceituais e as arestas são relações semânticas estabelecidas entre esses conceitos. Metodologia: A RSL seguiu a proposta de Kitchenham e foi implementada na ferramenta on-line Parsifal. A fim de fornecer amplitude à pesquisa, foram incluídos na condução metodológica, por meio de um tratamento de metadados, arquivos bib das fontes ACM, da ScienceDirect e da Engineering Village, o que aumentou a quantidade de documentos encontrados e analisados. Resultados: Como resultado verificou-se, em relação ao procedimento bibliométrico especializado, que a adição de bases acadêmicas resultou em um aumento da amplitude da busca em 56,8% e, consequentemente, nos resultados das análises bibliográficas e bibliométricas realizadas. Conclusão: Em relação aos documentos analisados, as conclusões mais relevantes foram: a) que o conceito de RSMC ainda não está formalizado na literatura acadêmica e b) que existe interesse continuado em práticas pedagógicas envolvendo, principalmente, mapas conceituais e, complementarmente, redes semânticas e relações semânticas lexicais no escopo de busca realizado. O estudo ora apresentado pode contribuir para qualificar a prática da revisão sistemática de literatura com a adoção de procedimentos bibliométricos suportados por ferramentas tecnológicas, como é o caso do pacote Bibliometrix.
Non Performing Financing di Masa Pandemi Covid-19 dan Strategi Menghadapinya
Authors: Hasanah Lailatul , Putra Safwira Guna
Published: September 2024

This research aims to answer how the impact of the COVID-19 pandemic on non-performing financing at PT BPRS Dinar Ashri Mataram and what are the strategies for dealing with and mitigating the financing risks. The analysis uses a descriptive qualitative approach. The primary data collected by direct observation and conducting semi-structured interviews with several employees by considering the position and job role of the employee.
The results showed that at the beginning pandemic, NPF ratio increased from 0.65% in 2019 to 0.77% in 2020. However, in 2021 the NPF ratio decreased to 0.70%. This NPF ratio is still safe compared to the average national NPF ratio, this is due to the success of PT. BPRS Dinar Ashri implementing the right mitigation strategy which is, among others, awarenes to do restructuring financing facility which is experiencing a decline business conditions.
Analisis Pengaruh Promosi dan Jaminan Rasa Aman Terhadap Keputusan Memilih Tabungan Mudharabah Bank NTB Syariah Mataram
Authors: Sukmana Abdul Hadi , Muhammad Rido  , Sirrul Hayati
Published: September 2024

Dewasa ini, persaingan di sektor perbankan sudah sangat ketat, dan karena itu, supaya bank dapat bertahan, maka harus memperhatikan kegiatan promosi dan jaminan rasa aman sehingga dapat menarik pelanggan. Penelitian ini bertujuan untuk mengetahui pengaruh promosi, dan jaminan rasa aman terhadap keputusan nasabah menggunakan tabungan mudharabah di PT Bank NTB Syariah Mataram. Sampel penelitian terdiri dari 200 nasabah Bank NTB Syariah Mataram yang dipilih melalui teknik judgment sampling. Regresidengan software SPSS digunakan untuk analisis data dan pengujian hipotesis. Hasil penelitian menunjukkan bahwa promosi dan jaminan rasa aman berpengaruh secara simultan dan parsial terhadap keputusan nasabah menggunakan produk tabungan mudharabah PT Bank NTB Syariah Mataram. Temuan penelitian ini menunjukkan bahwa PT Bank NTB Syariah Mataram harus memperhatikan promosi dan jaminan rasa aman dalam rangka meningkatkan jumlah nasabah tabungan mereka.
ANALISIS PIOTROSKI F-SCORE PADA SAHAM JAKARTA ISLAMIC INDEX 70 PERIODE TAHUN 2019-2021
Authors: Sandiffu’ad Ahmad , Putra Safwira Guna
Published: September 2024

In investing, one of the analyzes that must be carried out by investors is to carry out fundamental analysis. One method that can be used to view company performance, especially the information contained in financial reports, is the Piotroski F-Score. This study relies on secondary data in the form of published company financial reports, then analyzed using a quantitative approach to measure the financial performance of each company. Data analysis was carried out by calculating the nine Piotroski F-Score assessment variables, then giving a score to each of these criteria. The sampling technique used purposive sampling where only 55 companies were included in the sample criteria. The results showed that the use of the Piotroski F-Score was able to show Islamic stocks with good performance as seen from the high Piotroski F-Score values ??for companies included in the Jakarta Islamic Index 70 for the 2019-2021 period. Of the 55 samples analyzed, there were 34 stocks that had scores in the range of 0-3 which were categorized as companies with low performance, investors were recommended to avoid or not invest in these companies. And there are 21 companies that have a score of 4? ???????????? ? 7 which are categorized as companies with medium performance which are eligible for investment.In investing, one of the analyzes that must be carried out by investors is to carry out fundamental analysis. One method that can be used to view company performance, especially the information contained in financial reports, is the Piotroski F-Score. This study relies on secondary data in the form of published company financial reports, then analyzed using a quantitative approach to measure the financial performance of each company. Data analysis was carried out by calculating the nine Piotroski F-Score assessment variables, then giving a score to each of these criteria. The sampling technique used purposive sampling where only 55 companies were included in the sample criteria. The results showed that the use of the Piotroski F-Score was able to show Islamic stocks with good performance as seen from the high Piotroski F-Score values ??for companies included in the Jakarta Islamic Index 70 for the 2019-2021 period. Of the 55 samples analyzed, there were 34 stocks that had scores in the range of 0-3 which were categorized as companies with low performance, investors were recommended to avoid or not invest in these companies. And there are 21 companies that have a score of 4? ???????????? ? 7 which are categorized as companies with medium which are eligible for investment.
PENGARUH PEMBIAYAAN MURABAHAH, TABUNGAN WADI’AH DAN DEPOSITO MUDHARABAH TERHADAP PROFITABILITAS (ROA) PADA BANK NTB SYARIAH KANTOR PUSAT KOTA MATARAM
Authors: Azizoma Rusman , Sumiati
Published: September 2024

This study aims to determine the effect of murabahah financing, wadiah savings and mudharabah deposits on profitability (ROA) at NTB Syariah banks for the 2019–2021 period. This type of research is quantitative research using secondary data from the monthly financial reports of Bank NTB Syariah for the 2019-2021 period and analyzed and processed using SPSS. The results of this study indicate that murabahah financing has a significant effect on profitability (ROA) with a significant level of 0.00 <0.05. Wadiah savings have a significant negative effect on profitability (ROA) with a significant level of 0.002 <0.05. Mudharabah deposits have a significant effect on profitability (ROA) with a significant level of 0.025 > 0.05. an influence contribution of 89.7%.
ANALISIS PENGETAHUAN MASYARAKAT DALAM MENGGUNAKAN PRODUK BANK SYARIAH (STUDI DESA BONDER KECAMATAN PRAYA BARAT)
Authors: Baiq Erma Widiarty  , Imronjana Syapriatama  , Nurul Susianti
Published: September 2024

The main thing in this thesis is that the majority of the people of Bonder Village, West Praya Subdistrict, are Muslims, but the people of Bonder Village, West Praya Subdistrict, make more transactions using conventional banks. In this study, the researcher aims to explain and describe the extent of public understanding of Islamic banks and the products available at Islamic banks in Bonder Village, West Praya District. This type of research is descriptive, namely interviews with the community of Bonder Village, West Praya Subdistrict using qualitative methods that describe the community's knowledge of Islamic bank products. Techniques in data collection, the author uses observation, interviews, documentation with the people of Bonder Village, West Praya Subdistrict and data validity assurance techniques the author uses research, namely tringulation theory, after which the author draws conclusions to conclude all the information that has been obtained. The results of the research can be concluded that first, the people of Bonder Village, West Praya Subdistrict generally do not understand the difference between Islamic banks and conventional banks and second, the people of Bonder Village generally do not understand what the products are in Islamic banks.
PENGARUH LITERASI KEUANGAN DAN INKLUSI KEUANGAN TERHADAP KEPUTUSAN MAHASISWA DALAM MENGGUNAKAN PRODUK DAN JASA BANK SYARIAH
Authors: Ritonga Alawiyah Ade Lazriyani , M. Yarham
Published: September 2024

This research aims to see the effect of financial literacy and financial inclusion on student decisions in using Islamic bank products and services. The type of research used in this research is quantitative with data collection techniques used are questionnaires and questionnaires. The method of determining the sample using the slovin formula obtained 100 research respondents. The data analysis technique uses Structural Equation Modeling (SEM) with the help of SPSS. This study shows that financial literacy and financial inclusion variables have a positive and significant impact on student decisions in using Islamic bank products and services.
This research is expected to be able to change the mindset of students towards the use of products and services of Islamic banks. Then it is expected that students use Islamic financial services not on the basis of literacy or inclusion but pay attention to the application of sharia.
Islamic Corporate Social Responsibility Disclosure, Profitability, and Visibility of Sharia Commercials Bank in Indonesia
Authors: Akmal Denara
Published: September 2024

The purpose of this study is to analyze the effect of profitability and visibility on Islamic Corporate Social Responsibility Disclosure (ICSRD) of Islamic Commercial Banks in Indonesia for the period 2020 – 2022. This research is a quantitative study using secondary data from the Islamic Commercial Bank's Annual Reports and Sustainability Reports. The effects are examined based on content analysis of 9 Islamic Commercial Banks in Indonesia using a  purposive sampling technique. The results showed that profitability and visibility simultaneously had a significant effect on the ICSRD of Islamic Commercial Banks in Indonesia for the period 2020 – 2022. However, partially the profitability did not affect ICSRD. Meanwhile, the visibility has a significant effect on ICSRD partially. The results of this study are expected to provide a reference for Islamic Commercial Banks policymakers to always improve the ICSR to maintain customer confidence in the operations of Islamic Commercial Banks in Indonesia.
Validation of the Jamaican version of the Oral Health Impact Profile (OHIP-14) in adults: JAM-OHIP study
Authors: Brown Michelle Antonette , Thomas Biney , De Souza Juliana Sena , Soares Rech Rafaela , Santosh Arvind Babu Rajendra , Baumgarten Alexandre , Campbell-Blagrove Susanna
Published: September 2024

Background: The Oral Health Impact Profile (OHIP-14) is a widely used tool for measuring the effects of oral health-related quality of life (OHRQoL). However, the validity of the OHIP-14 in the Jamaican context, referred to as the Jamaican Oral Health Impact Profile (JAM-OHIP), has yet to be established. Purpose: To determine the validity of the Jamaican language version of the OHIP in evaluating the OHRQoL of Jamaican adults. Methods: The original English version of the Oral Health Impact Profile (OHIP-14) was translated into the Jamaican language using forward and backward translation. The JAM-OHIP was used to evaluate the OHRQoL of 236 individuals at the University of the West Indies Dental Polyclinic. The overall fit was checked using a chi-square test (p > 0.05), comparative fit index (CFI), Tucker–Lewis index (TLI), root mean square error of approximation (RMSEA), and standardized root mean square residual (SRMR). Results: More DMFT (p < 0.01) was associated with high JAM-OHIP scores, and the most impacted domain was physical pain. Cronbach’s alpha and the standardized item alpha for the JAM-OHIP were 0.82. The overall fitting results for the CFA were χ²(68) = 80.558, p = 0.142, and χ²/g.l. = 1.185. The CFI and TLI were 0.996 and 0.994, respectively. The SRMR was 0.072 and the RMSEA was 0.028 (CI95% = [0.000; 0.050]) p = 0.953. Conclusions: The JAM-OHIP instrument was shown to be reliable and valid for the assessment of OHRQoL in the Jamaican adult population.
Determinant factors of procrastination behavior at work: A case study in the university context
Authors: Sunarta Sunarta , Muafi Muafi
Published: September 2024

Procrastination, or delaying or postponing something frequently, is often found at workplace including university staff. Many factors in personal characteristics, task characteristics, and organizational work settings can cause procrastination. The existing empirical literature on procrastination focuses mainly on student procrastination, with little attention paid to the procrastination patterns of academic staff. Therefore, by using social exchange theory, this study aims to discuss the factors that influence procrastination behavior in academic staff. This research examines the influence of achievement motivation, job satisfaction, and psychological contract fulfillment on procrastination directly or through organizational commitment. The study was conducted through a case study approach. This research uses a quantitative approach with a survey research design of 126 staff at one of the state universities in Yogyakarta. The research instrument was developed from previous research. The data were analyzed using partial least square (PLS) based on structural equation modeling (SEM). The research results show that only achievement motivation and organizational commitment have a negative influence on procrastination. Organizational commitment mediates the influence of achievement motivation on procrastination. Job satisfaction and fulfillment of the psychological contract do not directly influence procrastination yet through organizational commitment. The results of this research provide implications for the role of human resource management in controlling procrastination at work. In the university context, achievement motivation and organizational commitment have a dominant influence in controlling procrastination behavior.
Multiphysics Studies of 3D Plate Fin Heat Exchanger Filled with Ortho-Para- Hydrogen Conversion Catalyst for Hydrogen Liquefaction
Authors: Tang Liangguang , Yamaguchi Doki , Orellana Jose , Tian Wendy
Published: September 2024

A comprehensive 3D Multiphysics model was developed to simulate a plate fin heat exchanger designed for hydrogen liquefaction, incorporating ortho-para- hydrogen conversion catalyst in the hot fin channel. The model encompassed the 3D serrate fin structure, turbulent flow within the cold fin channel, and porous flow through the catalytic hot fin channel. Species transportation within the hot fin channel is coupled with ortho-para hydrogen conversion kinetics, while heat transfer mechanisms between the hot and cold fin channels are rigorously accounted for. Addi-tionally, the state- of- art equation of state is employed to accurately describe the thermodynamic properties of ortho- and para- hydrogen within the model. Numerous operational parameters, including the gas hourly space velocity, cold gas velocity, ortho-para- hydrogen conversion ki-netics, and operating pressure, were systematically varied to identify the kinetic and heat transfer constraints during the heat exchanger operation. The findings revealed that the ortho-para- hy-drogen conversion kinetic parameter predominantly governs operations requiring high gas hourly space velocity, particularly in large- scale hydrogen liquefaction processes. Furthermore, significant pressure drop within the catalytic filled channel was observed, however, operating at higher pressure mitigates this issue while mildly enhancing ortho-para-hydrogen conversion kinetics.
A Review of the Application of Hyperspectral Imaging Technology in Agricultural Crop Economics
Authors: Hu Pengfei , Wu Jinxing , Wu Yanying , Zhang Yi
Published: September 2024

China is a large agricultural country, and the crop economy has an important place in the national economy. The identification of crop diseases and pests, as well as the non-destructive classification of crops, has always been a challenge in agricultural development, hindering the rapid growth of the agricultural economy. Hyperspectral imaging technology combines imaging and spectral techniques, using hyperspectral cameras to acquire raw image data of crops. After correcting and preprocessing the raw image data to obtain the required spectral features, it becomes possible to achieve rapid non-destructive detection of crop diseases and pests, as well as non-destructive classification and identification of agricultural products.
This paper first provides an overview of the current applications of hyperspectral imaging tech-nology in crops both domestically and internationally. It then summarizes the methods of hyper-spectral data acquisition and application scenarios. Subsequently, it organizes the processing of hyperspectral data for crop disease and pest detection and classification, deriving relevant pre-processing and analysis methods for hyperspectral data. Finally, it conducts a detailed analysis of classic cases using hyperspectral imaging technology for detecting crop diseases and pests and non-destructive classification, while also analyzing and summarizing the future development trends of hyperspectral imaging technology in agricultural production.
The non-destructive rapid detection and classification technology of hyperspectral imaging can effectively select qualified crops and classify crops of different qualities, ensuring the quality of ag-ricultural products. In conclusion, hyperspectral imaging technology can effectively serve the ag-ricultural economy, making agricultural production more intelligent and holding significant im-portance for the development of agriculture in China.
Enhancing Strength and Performance of Self-Compacting Concrete for Integration in Department of Public Works and Highways Projects: A Value Engineering Approach
Authors: Rivera John Philip
Published: September 2024

This research paper investigates the enhancement of strength and performance of self-compacting concrete (SCC) for integration in Department of Public Works and Highways (DPWH) projects using a value engineering approach. The study explores key elements of SCC's strength and performance, including mix design optimization, construction practices, and durability considerations. Strategies to optimize SCC's strength, durability, and workability are discussed, emphasizing the benefits of SCC in improving construction efficiency and quality control within DPW infrastructure. The study also identifies challenges and gaps in SCC utilization, such as standardized performance verification and cost considerations, and proposes future directions for advancing SCC technology in civil infrastructure development.
The Level and Limitations of Physical Activity in Elderly Patients with Diabetes
Authors: Biernat Karolina , Marciniak Dominik M. , Mazurek Justyna , Kuciel Natalia , Hap Katarzyna , Kisiel Michał , Sutkowska Edyta
Published: September 2024

Background: Old age and illnesses can limit physical activity (PA). Objectives: To assess the level of PA and its limitations. Design: Cross-sectional study, January and June 2024. Setting: Diabetes Center. Subjects: Patients (N=207) >64 years with diabetes (DM). Methods: Surveying using: IPAQ, Accompanying Survey (AS). The significance was assessed by: Student’s t-test, Mann-Whitney U test, Pearson’s test. The relationships between the IPAQ and the AS results were analyzed based on a meta-analysis model for variable effects, OR with a 95% CI. ROC curve was used to determine the threshold values for age, BMI. Correlations between selected key variables were evaluated using the PCA. Results: The median age: 72 years (65–87), BMI: 28.70 kg/m2 (18.61–49.69). The median PA level: 1,837 MET-min/week (0–9,891). The individuals who obtained insufficient (n=28), sufficient (n=75), and high levels of PA (n=53) were 17.95%, 48.08%, and 33.97%, respectively. Diseases were the main factor limiting PA (53,54%) in patient’s opinion, followed by the lack of a companion or motivation. The meta-analysis found no diseases linked to insufficient PA, but those with BMI > 33.3 kg/m² and over 75 years old more often had insufficient PA. PCA revealed several characteristics that predispose individuals to insufficient PA. Conclusions: People over 75 years of age tend to avoid PA more than younger seniors, leading to its insufficient level, similarly like higher BMI. The individual with DM who has an insufficient level of PA is typically a single, woman, over 75, BMI>33.
CBD-X Extracts in Asthma Management: Reducing Th2-Driven Cytokine Secretion and Neutrophil/Eosonophil Activity
Authors: Aswad Miran , Pechkovsky Antonina , Ghanayiem Narmeen , Dotan Yaniv , Louria-Hayon Igal
Published: September 2024

Background/Objectives: Asthma is a chronic inflammatory disorder of the airways affecting over 10% of the global population. It is characterized by airway inflammation, mucus hypersecretion, and bronchial hyperresponsiveness, driven predominantly by type 2 helper T cells (Th2) and type 2 innate lymphoid cells (ILC2s) in a subset of patients. However, a significant portion of asthmatic individuals present with "type 2-low" asthma, often refractory to standard inhaled corticosteroid (ICS) therapy. Therefore, developing innovative therapeutic strategies has become essential. Recent studies have highlighted cannabidiol (CBD) as a promising anti-inflammatory agent capable of modulating immune responses. This study investigates the therapeutic potential of a high-CBD extract (CBD-X) in asthma; Methods: We evaluated the effects of CBD-X on cells involved in asthma pathogenesis using primary human Th2 cells, neutrophils and asthma mouse model; Results: Our findings indicate that CBD-X extract inhibits Th2 differentiation and reduces the secretion of IL-5 and IL-13, which are crucial cytokines in asthma. Additionally, CBD-X significantly reduces pro-inflammatory cytokines IL-8 and IL-6 in neutrophils and impairs their migration, a critical step in airway inflammation. In a murine asthma model, CBD-X administration led to marked downregulation of IgE and pro-asthmatic cytokines, along with reduced leukocyte, eosinophil, and neutrophil infiltration in lung tissues; Conclusions: These results suggest that CBD-X extract could offer a novel, complementary approach to managing both type 2-high and type 2-low asthma by targeting key inflammatory pathways and modulating immune cell behavior.
Multi-objective Evolutionary Optimization of Transonic Natural Laminar Flow Wing at High Reynolds Number
Authors: Luo Shaojun , Tang Zhili , Chen Yongbin
Published: September 2024

Drag reduction by laminarization, an innovative technology in aerodynamics design, provides the possibility to improve significantly the aerodynamic performance of aircraft and remains to be one of the most promising and effective technologies. In this paper, the design method for transonic natural laminar flow (NLF) wing at high Reynolds number is investigated in details and a new optimization model is established to solve conflicts between the increase of a laminar flow region and the shock wave strength at the trailing edge. In order to numerically handle this competitive situation efficiently, a two-objective hierarchical variable fidelity Pareto evolutionary optimization model based on search space contraction is proposed and implemented. Numerical experiments show that it can capture simultaneously a Pareto front of the two-objectives: a wave drag minimization and a laminar flow region maximization. The results also show that both wave drag and skin friction drag performances of non-dominated Pareto members can be significantly improved via the optimal laminar wing shape and shock wave control device. Nearly 40% of the laminar flow area on the wing surface is achieved at the Reynolds number of 107. It is concluded that the present hierarchical variable-fidelity multi-objective evolutionary optimization method is computationally efficient, and illustrate its potential for solving complex engineering design problems.
Various Grids in Moiré Measurements
Authors: Saveljev Vladimir
Published: September 2024

The moiré effect is typically observed in regular periodic structures and sometimes in random (aperiodic) structures. However, only regular structures were used in measurements. In this study, we propose structures whose images are not regular but not completely random, and resemble a series of lines, such as a grid of dotted lines or a matrix of dots. A relatively simple image processing technique can make the moiré effect in such structures very similar to regular structures. We demonstrated using five different structures (including text) in measurements, with similar results.
Machine Learning Model Trained with Finite Element Modeling Can Predict the Risk of Osteoarthritis: Data from the Osteoarthritis Initiative
Authors: Mononen Mika E. , Liukkonen Mimmi K. , Turunen Mikael J.
Published: September 2024

Objective: Despite long simulation times, recently developed finite element analysis (FEA) models of knee joints have demonstrated their suitability for predicting individual risk of onset and progression of knee osteoarthritis. Therefore, the objective of this study was to assess the feasibility of machine learning (ML) to replicate outcomes obtained from FEA when simulating mechanical responses and predicting cartilage degeneration within knee joint.

Design: Two ML models based on the Gaussian Process Regression (GPR) algorithms were developed. The first model (GPR1) utilized age, weight, and anatomical joint dimensions as predictor variables to predict tissue mechanical responses and cartilage degeneration based on FEA data. The second model (GPR2) utilized age, weight, height, and gender to predict anatomical joint dimensions, which were then used as inputs in the GPR1 model. Finally, the GPR1 and combined GPR1+GPR2 models were used to investigate the importance of clinical imaging when making personalized predictions for knees from healthy subjects with no history of knee injuries.

Results: In the GPR1 model, R2 of 0.9 was exceeded for most of the predicted mechanical parameters. The GPR2 model was able to predict knee shape with R2 of 0.67 - 0.9. Both GPR1 and combined GPR1+GPR2 models offered equally good performance (AUC = 0.73 - 0.74) at classifying patients at high risk for the onset and development of knee osteoarthritis.

Conclusions: In the future, real-time and easy-to-use GPR models may provide a rapid technology to evaluate mechanical responses within knee for researchers or clinicians who have no former knowledge from FEA.
Impact of ADA Guidelines and Medication Shortage on GLP-1 Receptor Agonists Prescribing Trends in the UK: A Time-Series Analysis with Country-Specific Insights
Authors: Ibrahim Ahmed R. N. , Orayj Khalid M.
Published: September 2024

Background: Several GLP-1 receptor agonists (GLP-1 RAs) are used to treat type 2 diabetes (T2DM). Their cardio- and renal protective effects and substantial weight loss have been evident and progressively expanded their role in the American Diabetes Association (ADA) guidelines, which are endorsed by the European Association for the Study of Diabetes (EASD). The increased demand leads to a global shortage. Methods: We utilized a repeated cross-sectional design, drawing data from national prescribing databases, to analyze six GLP-1 RAs: Dulaglutide, Enatide, Liraglutide, Lisenatide, Semaglutide, and Tirzepatide. AutoRegressive Integrated Moving Average (ARIMA) models with exogenous variables were applied to assess trends over time and regions. Results: The prescription rates significantly differ between regions. Wales shows the highest prescribing for most GLP-1 RAs. The ARIMA models indicated a significant increase in their prescribing after ADA guidelines 2022 (e.g., Dulaglutide: Post-ADA effect of 15.22, 95% CI: [12.97, 17.47]). Following GLP-1 RAs shortages in July 2023, the prescribing rates, particularly for Semaglutide, increased (Shortage effect: 74.36, 95% CI: [71.92, 76.80]). Model diagnostics, including the Akaike Information Criterion (AIC) and Durbin-Watson statistics, confirmed the robustness of these trends. Conclusion: Informed decisions should be made by considering prescribing trends before and after important events such as the issuing of new guidelines or safety alerts.
Prioritising Polysomnography in Children with Suspected Obstructive Sleep Apnoea: Key Role of Symptom Onset and Sleep Questionnaire Scores
Authors: Nosetti Luana , Zaffanello Marco , Simoncini Daniela , Dellea Gaia , Vitali Maddalena , Amoudi Hajar , Agosti Massimo
Published: September 2024

Background/Objectives: Obstructive Sleep Apnoea Syndrome (OSA) in children disrupts standard breathing patterns and sleep architecture, potentially leading to severe consequences. Early identification and intervention for OSA are crucial to prevent these issues. This study explored the relationships between waiting times for polysomnography (PSG), clinical history, age at the time of PSG, and PSG outcomes in children; Methods: Two hundred and fourteen children were prospectively enrolled. Data were extracted from medical records on the age at referral for PSG and at the time of its execution, the waiting time for PSG, diagnosis (primary snoring, mild, moderate, and severe OSA), history of snoring and apnoea, medications taken, surgical interventions, passive smoke exposure, and allergies. The records also included the Pediatric Sleep Questionnaire (PSQ); Results: The mean age at referral for PSG was 5.2 (2.8) years, the waiting time for PSG was 5.2 (5.0) months, and the age at the time of PSG was 5.6 (2.8) years. Children with a shorter history of OSA (≤12 months) underwent PSG at an earlier age (4.9 (2.7) years) compared to those with a more extended history (6.0 (2.7) years; p=0.006). A younger age at referral for PSG was associated with a lower PSQ score (r=0.167; p=0.015), a shorter history of apnoea (r=0.216; p=0.003) and snoring (r=0.187; p=0.023), but also with greater OSA severity, expressed as oxygen desaturation index (r=-0.152; p=0.026). In the correlation analysis, the waiting time for PSG, adjusted for age at referral, was longer in children with a prolonged history of apnoea (r=0.195; p=0.023) and snoring (r=0.259; p=0.002) but with a lower PSQ score (r=-0.172; p=0.045); Conclusions: Some children receive delayed treatment, increasing the risk of long-term complications. In evaluating children with suspected OSA, the duration of symptoms and the PSQ score at referral emerge as crucial factors that should be considered to optimise prioritisation for PSG access.
Contextualização sobre o cumprimento das medidas socioeducativas no estado do Mato Grosso: uma revisão da literatura
Authors: Machado Vanuza Gomes Lima , Fensterseifer Daniel Pulcherio
Published: September 2024

Este artigo científico apresenta uma revisão da literatura sobre o funcionamento das medidas socioeducativas no estado do Mato Grosso. O objetivo é investigar como essas medidas estão sendo cumpridas e qual a sua efetividade nesse ambiente em particular. Ademais, os resultados obtidos servirão para contextualizar estudos mais amplos que envolvam o direito à educação de jovens restringidos de sua liberdade. A pesquisa foi conduzida por meio de uma revisão bibliográfica, utilizando critérios de inclusão e exclusão para a seleção dos artigos. A busca foi realizada em bases de dados relevantes, como o Portal de Periódicos da CAPES e a SciELO. Os resultados e as discussões foram apresentados de forma explanatória, permitindo ao leitor avaliar as principais conclusões e implicações derivadas dos estudos revisados. Essa pesquisa contribui para o conhecimento sobre o funcionamento das medidas socioeducativas no Mato Grosso, oferecendo subsídios para a compreensão e aprimoramento desse sistema no contexto local. Os resultados evidenciaram os desafios a serem enfrentados para o aprimoramento do sistema socioeducativo, o qual deve buscar oferecer elementos que possam colaborar para uma formação cidadã dos jovens. Espera-se que os achados desta pesquisa sirvam para contribuir com ações e políticas públicas voltadas para a melhoria e efetividade das medidas socioeducativas no estado mato-grossense.
NON-ALCOHOLIC FATTY LIVER DISEASE AND ECHOCARDIOGRAPHIC PARAMETERS IN YOUNG ADULTS WITH CARDIOMETABOLIC RISK FACTORS
Authors:   Kazan State Medical University, ASATULLINA ZEMFIRA R. , SINEGLAZOVA ALBINA V. ,   Kazan State Medical University
Published: September 2024

Introduction. Non-alcoholic fatty liver disease, the most common chronic liver disease worldwide, may alter cardiac structure and function regardless of obesity, resulting in heart failure. Therefore, the association of changes in liver steatosis indices, as integral indicators of dysmetabolic processes, with changes in echocardiographic parameters is of interest. Aim. To study echocardiographic features in nonalcoholic fatty liver disease and the relationship between hepatic steatosis indices and cardiac structural and functional parameters. Materials and Methods. This “case-control” study performed in Kazan included 142 patients (74 males and 68 females) aged 35 [31-39] years. A full clinical examination was performed, including anthropometry, laboratory work-up, liver ultrasonography, and echocardiography. Non-alcoholic fatty liver disease–liver fat score, hepatic steatosis, and triglyceride and glucose indices were calculated. Data were processed using IBM SPSS Statistics 26. Results and Discussion. Ultrasonography revealed non-alcoholic fatty liver disease in 10.2% of individuals. Increased liver steatosis indices were observed in 64.8% of subjects. We found a simultaneous increase in two indices in 40.3%, and in all three indices in 14% of cases. In patients with non-alcoholic fatty liver disease, in contrast to obese subjects, we observed higher left ventricular myocardial mass (p=0.013), left atrial volume (p=0.033), end-diastolic dimension (p=0.016), end-systolic volume (p=0.022), and a trend towards higher left atrial dimension (p=0.084), interventricular septal thickness (p=0.076), end-diastolic volume (p=0.092), and lower left ventricular ejection fraction (p=0.017). The hepatic steatosis index and triglyceride and glucose index correlated with the cardiac structural and functional parameters (rs=0.176-0.424; p=0.000-0.039). Binary logistic regression demonstrated that higher hepatic steatosis index increased the likelihood of having a high normal left ventricular myocardial mass and high normal stroke volume, while an increase in triglyceride and glucose index was associated with a decrease in stroke volume (R2=0.132; p=0.000). Conclusions. The presence of nonalcoholic fatty liver disease in young adults with cardiometabolic risk factors is associated with changes in cardiac structural and functional parameters. Higher hepatic steatosis index increases the likelihood of a high normal left ventricular myocardial mass and high normal stroke volume, whereas an increase in triglyceride and glucose index increases the likelihood of low normal stroke volume.
Geç Osmanlı’dan Erken Cumhuriyet’e Türkiye’de Sınırların Tarihsel-Sosyolojik İnşası
Authors: Özbey Kerem
Published: September 2024

Sınırların tarihsel-sosyolojik açıdan inşası geleneksel toplumdan modern topluma dönüşüm sürecinde gerçekleştiğinden, Türkiye’de bu dönüşüm Osmanlı’nın son döneminden Cumhuriyet’in erken dönemine karşılık gelir. Bu çalışma, Türkiye’de sınırların tarihsel-sosyolojik açıdan inşasını anlamayı amaçlamaktadır. Osmanlı’dan Cumhuriyet’e geçiş, Türkiye’de sınırların imparatorluktan ulus-devlete, ümmetten ulusa ve coğrafyadan vatana dönüşümünü göstermektedir. Osmanlı’nın son döneminde devleti kurtarmakla sembolize edilen sınırlar, Cumhuriyet’e geçişle birlikte milliyetçilik temelinde Türk ulus-devletini inşa etmenin bir aracına dönüşmüştür. Kemalist Türk devrimi, modern, Batılı ve laik bir Cumhuriyet kurarak Osmanlı-İslami gelenekle arasına bir sınır çekmiştir. Kemalist milliyetçilik, Türk ulusal kimliğini Anadolu topraklarını çevreleyen sınırlar içinde inşa etmiş ve sınırlar bu kimliğin uçlarını oluşturmuştur. Osmanlı’dan Cumhuriyet’e geçiş Müslümanların vatan algılarını dönüştürmüş ve Anadolu toprakları yeni vatanın adı olmuştur. Kemalizm’in laiklik ilkesi, Türkiye’nin İslam dünyasındaki seküler sınırını sembolize etmektedir. “Hudut namustur” ve “anavatan” söylemleri, Türkiye’de sınırların milliyetçi-cinsiyetçi bir şekilde inşa edildiğini göstermektedir. Neticede, Türkiye’de sınırların modernleşme, din, sekülerizm, milliyetçilik, ulusal kimlik ve toplumsal cinsiyet kimlikleri bağlamında inşa edildiği gözlenmiştir.
A Prospective Study of the IlluminOss Photodynamic Nail System for Pelvic Stabilization
Authors: Lozano-Calderon Santiago A. , Gonzalez Marcos R. , Werenski Joseph O. , Quinn Kayla , Freiberger Diana , Raskin Kevin A.
Published: September 2024

Background:

The stabilization of metastatic lesions in the periacetabular region can be successfully performed using percutaneous techniques. Photodynamic nails (PDNs) are among the available tools for stabilization. Data on postoperative complications and functional outcomes are, however, scarce.

Methods:

Patients undergoing percutaneous stabilization using PDNs (IlluminOss Medical) for impending or actual minimally displaced pathological fractures of the pelvis from metastatic bone disease, multiple myeloma, or primary bone lymphoma were enrolled prospectively. Outcomes were assessed preoperatively and postoperatively at the 2-day, 2-week, 6-week, 3-month, 6-month, and 1-year time points. Functional outcomes assessed included the Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function, PROMIS Pain Interference, Combined Pain and Ambulatory Function (CPAF), EuroQol-Visual Analogue Scale (EQ-VAS), and Musculoskeletal Tumor Society (MSTS) scores. Pain was assessed using a VAS.

Results:

A total of 30 patients treated with PDNs were included. The median VAS pain score dropped from 60 points preoperatively to 30 at 6 weeks postoperatively (p = 0.004). The median CPAF score improved from 6 preoperatively to 7 postoperatively at the 6-week mark. The median EQ-VAS score showed significant improvement at 6 weeks (70 versus 50; p = 0.006). The median 2-week PROMIS Pain Interference score was significantly lower than preoperatively (64.1 versus 66.9; p = 0.03). An improvement in the median PROMIS Physical Function score was seen at 6 weeks following surgery compared with preoperatively (37 versus 30.1; p = 0.001). A significant improvement in the MSTS score was seen as soon as 2 days after surgery (77% versus 40%; p < 0.0001).

Conclusions:

Among patients with pelvic bone metastases, multiple myeloma, or primary bone lymphoma, we found that treatment using PDNs resulted in immediate return to ambulation and rapid functional outcome improvement, with low complication rates. In this population, this technique represents a safe alternative to open surgery.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Prediction of Overburden Failure on the Working Face Using Self-Formed Roadway Mining Technology without Coal Pillars Based on Microseismic Monitoring: A Case Study
Authors: Hu Bosheng , Wang Tong , Xie Panshi , Luo Shenghu
Published: September 2024

In this study, the No.S1201-II working face of a coal mine using self-formed roadway mining technology without coal pillars was used as the engineering background, and physical experiments, numerical simulations, and field measurements were employed to study the spatiotemporal evolution laws of overburden fracture and obtain the periodic breaking law of the overburden. The results revealed the following: (1) the working face length increased after roof cutting, which led to an increase in the roadway stress on the side away from the mined area. The roof displacement remained essentially unchanged when the roadway was in the digging and cutting stages. However, the roof displacement continued to increase during the sinking and forming stages. (2) The height of the fall zone before roof cutting was approximately 17.1–19.4 m, which was 4.3–4.8 times the mining height. The maximum heights of the fracture zone on both sides and in the middle of the working face were 103.6–106.4 m and 92.4–96.1 m, respectively, corresponding to 25.9–26.6 and 23.1–24.0 times the mining height, respectively. The height of the fall zone after roof cutting was approximately 18.1 m, which was 4.5 times the mining height. The maximum heights of the fracture zone on both sides and in the middle of the working face were 100.6–105.2 m and 91.3–95.2 m, respectively, corresponding to 25.1–26.3 and 22.8–23.8 times the mining height, respectively. (3) Combined with the ground pressure behaviors and overburden breakage monitored in the field, the fracture budding phase, fracture development phase, and fracture maturation phase were divided according to the characteristics of microseismic events. A criterion for overburden deformation damage based on microseismic energy was proposed. This study provides a reference for the establishment of a microseismic-monitoring system and the application of this technology.
Líneas de investigación de la Universidad
Authors:   Universidad Científica del Sur
Published: September 2024

Lineas de investigación de la Universidad Científica del Sur desarrolladas en el año 2017.
Lineamiento – Convalidación de horas extracurriculares vinculadas con investigación
Authors:   Universidad Científica del Sur
Published: September 2024

Lineamiento – Convalidación de horas extracurriculares vinculadas con investigación. Versión 1.0 (2021). Registro histórico. Ver la versión posterior en: https://repositorio.cientifica.edu.pe/handle/20.500.12805/3693