bluuebunny/crossref_metadata_2025 huggingface dataset:
Studying the Immunogenic Properties of Plague Microbe Capsule Antigen F1 Conjugated with Nanoparticles of Colloid Gold and Silver
Authors: Kireev M. N. , Polunina T. A. , Guseva N. P. , Podboronova N. A. , Krasnov Ya. M. , Taranenko T. M.
Published: December 2018

Influence of nanoparticles of colloid gold (CG) and silver (CS) on immunobiological properties of antigens and possibility of their application as adjuvants for antibody formation stimulation were studied. It was shown that F1 capsule antigen of plague microbe conjugated with nanoparticles of CG and CS possesses more strongly expressed immunogenic properties than original F1 antigen independently of the way of injection. Gold and silver sols with antigens are stable, capable to stimulate specific antibody generation subject to less antigen burden, comfortable for use, do not cause general and local reactions. All these facts give the opportunity to use them in immunologic practice as adjuvants when engineering immunobiological preparations.
Emerging and Re-Emerging Infections - a Dozing Volcano
Authors: L’vov D. K.
Published: December 2018

Questions discussed in this work concern the problem of emerging and re-emerging infections, in particular smallpox and avian flu caused by highly virulent strain H5N1. Data presented evidence the real threat that emerging and re-emerging infections pose to public health and the necessity to carry out fundamental investigations in this direction at national and international levels.
Application of PCR for Identification and Interspecific Differentiation of Glanders and Melioidosis Etiological Agents
Authors: Chuhlantsev D. A. , Marakulin I. V. , Darmov I. V.
Published: December 2018

Assessed were possibilities of identification and differentiation of glanders and melioidosis etiological agents by means of PCR method using different nucleotide sequences of the pathogenic Burkholderia. Primers perspective for inclusion in the test-system assigned for detection of glangers and melioidosis etiological agents DNA in environmental samples and biological materials were selected.
HFRS Natural Foci in the Republic of Mordovia
Authors: Churbanova T. A.
Published: December 2018

The landscape-ecologic zoning of HFRS natural foci was carried out. Three zones and 13 natural foci were ear-marked in the territory of the Republic of Mordovia. Places where people can be infected and the indices of HFRS immunity of the community in some natural foci were determined. As a result of epizootiologic investigation it was stated that 4.1 % of rodents were infected by Hantavirus. Continuous monitoring of HFRS natural foci is necessary to carry out modern preliminary prophylactics of this disease.
Epidemiological Regularities o f Plague in India and Substantiation of Measures on Sanitary Protection of Siberia and Far East Territories
Authors: Maramovich A. S. , Kosilko S. A. , Innokentieva T. I. , Voronova G. A. , Nikitin A. Ya. , Basanova L. P. , Okunev L. P.
Published: December 2018

Plague epidemiological situation in India in XX and at the beginning of XXI century is evaluated. The epidemic process is shown to have wavy interrupted course and is divided into periods of annual intensive epidemics, reduction of epidemic activity and sudden development of acute outbreaks on the background of sporadic morbidity absence. Brief characterization of a pulmonary plague epidemic in India in 1994 and undertaken international sanitary and protective measures by the example of Russian Federation and USA is presented. Local outbreaks of pulmonary and bubonic plague in 2002-2004 give evidence of periodically complicated epidemic situation in India. Trend and volume of measures on sanitary protection of territories are substantiated by development of commercial, economical, tourist communications between India and Russia including Regions of Siberian and Far Eastern Federal Districts differing by the degree of plague importation risk.
HFRS Morbidity Dynamics in Federal Districts of the Russian Federation from 2001 to 2007
Authors: Toporkov V. P. , Velichko L. N. , Shiyanova A. E. , Kouklev E. V. , Popov N. V. , Tarasov M. A. , Scherbakova S. A. , Karavaeva T. B.
Published: December 2018

The retrospective epidemiologic analysis of HFRS morbidity carried out from 2001 to 2007 showed that the highest sickness rate was registered in Privolzhsky federal district with 20.4±2.3 average index that exceeded the similar one countrywide 4-fold and the incidence specific weight was 88.0 % of the total number of cases. The indexes of HFRS incidence in the rest 6 dis­tricts were lower than the Russia wide one 3-4-fold and more. During the analyzed period the tendency to increase the HFRS incidence level was observed in Privolzhsky, Ural and Far East districts and in the country.
Comparative Morphometric Analysis of Experimental Plague Infection Caused by Yersinia pestis Strains with Different Genetic Characteristics
Authors: Bugorkova S. A. , Kouklev V. E. , Bugorkova T. V. , Malykhina Z. V. , Kutyrev V. V.
Published: December 2018

Data on adaptive-compensatory process formation in detoxication and adaptation functional systems of test animals during the plague infection modeling were obtained by means of morphometric analysis. The latter included characterization of apudocytes condition in the number of organs. Changes of apudocytes activity and quantity in immunocompetent organs and pulmonary tissue of biomodels were determined. Morphometric indices selected for registration were shown to allow characterizing the severity of experimental infectious process.
Production of Monoclonal Antibodies against Outer Membrane Proteins of Burkholderia pseudomallei, Strain C-141
Authors: Vetchinin S. S. , Kopylov P. C. , Kiseleva N. V. , Baranov A. M. , Baranova E. V. , Galkina E. V. , Borzilov A. I. , Kalachev I. Y.
Published: December 2018

Monoclonal antibodies (MAb) were produced against two B. pseudomallei high-purified membrane proteins with Mr 29 kDa (p29) and 45 kDa (p45). Monoclonal antibodies from culture supernatant fluids of 4F2 and 1G11 clones showed specific interaction with protein moiety of p29 both Burkholderia pseudomallei and Burkholderia mallei in ELISA and Western blotting. However, MAb of 3G4 clone were bound to the LPS-protein structures of these microbial cells. Analysis of interaction of Mabs from 4F2 and 1G11 clones with antigens of different lysates of pathogenic cells confirmed high specificity of these antibodies to p29 membrane protein of B. pseudomallei and B. mallei.
Metal Hypersensitivity in Total Joint Arthroplasty
Authors: Eftekhary Nima , Shepard Nicholas , Wiznia Daniel , Iorio Richard , Long William John , Vigdorchik Jonathan
Published: December 2018

* Metal hypersensitivity has been reported in various case reports and cohort studies. Type-IV (delayed-type) hypersensitivity to various implant metals, most frequently nickel, has been implicated in the pathogenesis of metal hypersensitivity.

* Currently, there are no guidelines for addressing suspected or known metal allergy preoperatively and there is no evidence-based support for either preoperative testing or routine use of hypoallergenic implants.

* Multiple diagnostic modalities are available for the workup of suspected metal hypersensitivity; the 2 most common are patch testing and lymphocyte transformation testing. However, the ability of these tests to diagnose disease and predict outcomes has not yet been demonstrated.

* Further research is warranted to help understand the prevalence, pathology, diagnosis, treatment, and potential avoidance of metal hypersensitivity.
Commonly Missed Injuries in the Patient with Polytrauma and the Orthopaedist’s Role in the Tertiary Survey
Authors: Stevens Nicole M. , Tejwani Nirmal
Published: December 2018

* Up to 81% of missed injuries in the initial evaluation of patients with trauma are orthopaedic in nature, and up to 35% of these injuries require surgical management.

* Systematic tertiary examinations are an integral part of the continuing evaluation of a patient with polytrauma.

* Orthopaedic surgeons should have a prominent role in the tertiary evaluation of patients with trauma.

* Examination should include inspection and palpation of all extremities, with particular attention paid to the hands and feet, where the majority of missed injuries occur.
Being highly productive in the Biomedical Sciences: A qualitative study of motivation and habits of high-throughput researchers
Authors: Nickenig Vissoci Joao Ricardo , Oliveira Aline Chotte de , Gil Nelly Moraes , Calvo Paulo , Stival Ney , Yen Talitha , Haglund Michael , Staton Catherine Ann
Published: December 2018

Background: Quantity, quality, and impact of scientific publications are used to assess national, institutional, and individual levels of research productivity. While the importance of quality research is stressed among the medical research community, minimal research has been conducted on analyzing which factors affect research productivity. Current literature assesses the quality of research institutions rather than that of individual researchers; there is also no research on the difference between high-impact researchers and other researchers. This study, conducted in 2015, sought to investigate the underlying reason for high-throughput authors' success by understanding their similar habits and motivations leading to high productivity.

Methods: The authors conducted a qualitative study via interviews of high-throughput researchers from around the world. Semi-structured interview scripts guided the interviews in accordance to the grounded theory method for qualitative studies. Broad themes from preliminary interviews were identified and explored in subsequent interviews.

Results: Qualitative analysis of participant interviews identified eight major themes: “Writing habits,” “Writing strategy,” “Previous training and writing experience,” “Major driver,” “Balancing volume and impact of publications,” “Ideal and non-ideal conditions,” “Timelines,” and “Role of networking on high-throughput productivity.” These themes are not exclusive nor required qualities of high-throughput researchers but highlight similarities and broadly unifying characteristics of these researchers.

Conclusion:This study identified the common qualities and attitudes of high-throughput researchers. We found common factors in most individuals that can be considered markers of high productivity.
The Effect of Implementing an Aseptic Practice Bundle for Anaesthetists to Reduce Postoperative Infections. Protocol for a Stepped Wedge, Cluster Randomised, Multi-Site Trial. The Anaesthetists Be Cleaner (ABC) Study
Authors: Merry Alan , Gargiulo Derryn A. , Bissett Ian , Cumin David , English Kerry , Frampton Christopher , Hamblin Richard , Hannam Jacqueline , Moore Matthew , Reid Papaarangi , Roberts Sally , Taylor Elsa , Mitchell Simon J.
Published: December 2018

Background: Postoperative infection is a serious problem in New Zealand, and internationally with considerable human and financial costs. Also, in New Zealand, certain factors that contribute to postoperative infection are more common in Māori and Pacific populations. To date, most efforts to reduce postoperative infection have focused on surgical aspects of care and on antibiotic prophylaxis, but recent research shows that anaesthesia providers may also have an impact on infection transmission. These providers sometimes exhibit imperfect hand hygiene and frequently transfer the blood or saliva of their patients to their work environment. In addition, intravenous medications may become contaminated while being drawn up and administered to patients. Working with relevant practitioners and other experts, we have developed an evidence-informed bundle to improve key aseptic practices by anaesthetists with the aim of reducing postoperative infection. The key elements of the bundle are the filtering of compatible drugs, context-relevant hand hygiene practices, and enhanced maintenance of clean work surfaces.
Methods: We will seek support for implementation of the bundle from senior anaesthesia and hospital leadership and departmental “champions”. Anaesthetic teams and recovery room staff will be educated about the bundle and its potential benefits through presentations, written material, and exemplar videos. We will implement the bundle in operating rooms where hip or knee arthroplasty or cardiac surgery procedures are undertaken in a five-site, stepped wedge, cluster randomised, quality improvement design. We will compare outcomes between approximately 5,000 cases before and 5,000 cases after implementation of our bundle. Outcome data will be collected from existing national and hospital databases. Our primary outcome will be days alive and out of hospital to 90 days, which is expected to reflect all serious postoperative infections. Our secondary outcome will be the rate of surgical site infection. Aseptic practice will be observed in sampled cases in each cluster before and after implementation of the bundle.
Discussion: If effective, our bundle may offer a practical clinical intervention to reduce postoperative infection and its associated substantial human and financial costs.
Meson formation in mixed-dimensional t-J models
Authors: Grusdt Fabian , Zhu Zheng , Shi Tao , Demler Eugene
Published: December 2018

Surprising properties of doped Mott insulators are at the heart of
many quantum materials, including transition metal oxides and organic
materials. The key to unraveling complex phenomena observed in these
systems lies in understanding the interplay of spin and charge degrees
of freedom. One of the most debated questions concerns the nature of
charge carriers in a background of fluctuating spins. To shed new light
on this problem, we suggest a simplified model with mixed
dimensionality, where holes move through a Mott insulator
unidirectionally while spin exchange interactions are two dimensional.
By studying individual holes in this system, we find direct evidence for
the formation of mesonic bound states of holons and spinons, connected
by a string of displaced spins – a precursor of the spin-charge
separation obtained in the 1D limit of the model. Our predictions can be
tested using ultracold atoms in a quantum gas microscope, allowing to
directly image spinons and holons, and reveal the short-range hidden
string order which we predict in this model.
Inflows and outflows of mutual funds: a performance comparison of funds offered by traditional banks, insurance companies and mutual fund companies
Authors: Hsieh Lu-Chen , Lin Ying-Shing
Published: December 2018

The transformations in internet technology and financial innovation have led to the prevalence of direct finance, causing indirect finance to contract and concerns among traditional banks and insurance channel operators to seek transformation to innovate traditional services with advanced technology applications. The research compares the sales revenue flows of traditional banks, insurance companies, and mutual fund institutions, using quantile regression methods with five mutual fund factors: Jensen’s indexes, expenses, risks, sizes, and turnover rates. The sample statistics from 2001 to 2016 were evident, showing the results that sales revenue flows of bank and insurance companies did not decrease when compared to institutional fund investors, but instead, grew substantially, owing to the significant relationship of better technological services and financial innovation by banks and insurance companies. The research contribution is to point out that financial industry should focus, review and strengthen its most competitive core services inside, which are less challenged by outside competitors. By adhering to financial innovation and internet technology, it is still possible for traditional banks and insurance channels to gain substantial market shares with concentration on their core competitive services.
Influence of advertisement on customers based on AIDA model
Authors: S. Ullal Mithun , Thonse Hawaldar Iqbal
Published: December 2018

The paper is based on information which is a combination of store advertisement and consumers’ path inside the store along with product information. With this information, the authors find how advertisement affects the behavior of consumers when making the decision. The findings suggest that advertisement has a small impact on customers inside the stores. Null effect is determined, and one standard deviation in advertising has an impact on store traffic by 1.2%. But the impact at a lower end of the model is observed. One standard deviation in advertisement has impacted the store sales by 8.4%. Based on further data mining, the research has found that there is no significant improvement in the number of customers, but the increase in sales is because of the higher quantity of purchases by the existing consumers. However, the effect of advertisement on products placed in the same or nearby shelf is not found, the impact on product varieties in the same segment is also not found. Based on these research findings, the authors find the right approach towards advertisement.The research is limited to consumers of retail industry in a Tier 3 Indian city of a developing geographic segment only.
The role of corporate culture and ethical environment in directing individuals’ behavior
Authors: R. Y. Abu Arrah Tarek , Caglar Dilber , Bayram Pelin
Published: December 2018

This study is aimed at verifying the conception that a strong corporate culture supported with a positive ethical environment is central for directing and guiding the behavior of individuals toward achieving organizational objectives. The rationale for this study stems from the circumstance that formal controls systems suffer from consecutive failures, as the performance of organizations is still suffering from financial collapses. Reasons behind such failures might be related to the insufficient appreciation of the culture-based controls given that formal controls are influenced by the human nature of employees and the affixed moral side.Data subject to analysis are obtained from a judgmental sampling method using a self-completion questionnaire covering the listed companies at Jordan Securities Commission. A factor analysis and a standard multiple regression analysis have been conducted with the aim of proving the hypotheses of the research. The research results show that strong corporate culture supported with a positive ethical environment can direct the behavior of employees for the good of organizations. Results also support the importance of involvement of top management considering its role in filling the gap between the embraced and the workable values and beliefs of an entity.
Management of chronic venous insufficiency of the lower extremities
Authors: Kudykin M. N.
Published: December 2018

The article presents up-to-date information about epidemiology, pathogenesis and clinical manifestations of chronic venous diseases and chronic venous insufficiency of the lower extremities. It discusses the mechanism of action of various phlebotrophic drugs intended for the treatment of symptoms of chronic venous diseases and chronic venous insufficiency and describes the advantages of micronized purified flavonoid fraction for the treatment of all clinical classes of chronic venous diseases.
Topical use of antibiotics in the treatment of wound infections as exemplified by the effects of neomycin
Authors: Rodin A. V. , Danilenkov V. V. , Privolnev V. V.
Published: December 2018

The problem of effective treatment of the local surgical soft tissue infection has not yet been completely solved. The use of topical antibiotics, in particular neomycin, is one of the possible ways to solve this problem. The use of topical drugs that contain neomycin or combinations of neomycin and other antibiotics showed high efficacy of these drugs in the comprehensive treatment of wounds in various pathologies in combination with a low incidence of undesirable reactions.
Painkillers in the outpatient surgery setting Instructions for use of instructions
Authors: Zubkov D. S.
Published: December 2018

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The influence of prolonged antithrombotic therapy on the development of post-thrombotic syndrome in patients with proximal deep vein thrombosis of the lower limbs
Authors: Petrikov A. S. , Dudin D. V. , Zaitsev S. V. , Eirikh V. R. , Belykh V. I. , Shoikhet Ya. N.
Published: December 2018

The article is devoted to the incidence and severity of post-thrombotic syndrome (PTS), the odds ratio (OR) of PTS development in patients with previous proximal deep vein thrombosis (DVT) against the background of prolonged antithrombotic warfarin and sulodexide (SD) therapy (ATT) with due account for safety and development of clinically significant bleeding (CSB) during the year. A total of 130 patients aged 18 to 69 years with acute proximal DVT were enrolled in the comparative prospective study. Group I included 64 patients (31 men and 33 women), who received vitamin K antagonists (warfarin) therapy. Group II included 66 patients (37 men and 29 women), who received sulodexide in 3 months after completing a course of standard ACT (heparins in the acute period with the transition to AVK). The studied parameters included OR, incidence and severity of PTS in patients according to the Villalta scale, and the incidence rate of PTS against the background of prolonged warfarin and sulodexide ATT in 12 months’ time. It was established that the prolonged sulodexide ATT within one year after completing a course of standard ACT in patients with proximal DVT reduced the development of clinical signs of PTS by 22.2% compared to the standard warfarin therapy. At the same time, there is a lower incidence of severe forms of PTS in patients, who underwent proximal venous thrombosis, 17.8% against the background of sulodexide treatment. Thus, the prolonged sulodexide ATT is associated with a 1.7-fold decrease in the risk of the development of both PTS and its severe forms. Therefore, the prolonged use of sulodexide for one year in patients, who underwent proximal DVT, provides an alternative to warfarin and is associated with a lower incidence of PTS, including its severe forms. The prolonged sulodexide ATT is safe and does not cause the development of clinically significant hemorrhagic complications during the year.
Políticas econômicas anticíclicas e seus efeitos regionais e setoriais utilizando um modelo de equilíbrio geral computável inter-regional
Authors: NUNES Marivia de Aguiar
Published: December 2018

Nesta pesquisa, estimaram-se os efeitos de uma política de redução de tributos indiretos. Para tanto, a opção foi pela realização de um exercício, avaliando os efeitos de medidas de incentivo ao consumo implementado pelo governo federal em 2008/2009 em ações anticíclicas. A avaliação utilizou o modelo de Equilíbrio Geral Computável (EGC) adaptado à economia brasileira, o TERM-BR (The Enormous Regional Model). Os resultados apontam para um sucesso relativo das medidas em produzirem resultados positivos na economia brasileira, ainda que sob grande heterogeneidade regional.
O endomarketing como elemento motivador: Estudo de caso do Banrisul
Authors: GIL Daniela
Published: December 2018

Este artigo procura demonstrar a relevância do endomarketing nas organizações, tendo como objetivo descobrir qual a percepção dos funcionários sobre o endomarketing realizado pelo Banrisul. O colaborador satisfeito torna-se um verdadeiro "embaixador da marca", transmitindo, a partir de suas atitudes e informações, uma imagem favorável para os demais públicos da empresa.  O estudo se embasou em referencial teórico sobre endomarketing, comunicação organizacional e gestão de pessoas. A coleta de dados foi realizada por meio um questionário estruturado encaminhado, via e-mail interno, a todo o quadro da Direção Geral da empresa, obtendo respostas de 550 colaboradores, caracterizando uma amostra não probabilística, por conveniência. Contatou-se que os funcionários reconhecem ações de endomarketing realizadas pela empresa visando melhoria de sua qualidade de vida, principalmente no campo da saúde e educação. Entretanto, existe um trabalho de motivação a ser realizado pelo Banrisul, incrementando o feedback aos funcionários, priorizando um canal mais enxuto de informações e criando uma nova ferramenta onde os colaboradores possam emitir suas opiniões, sugestões e comentários à Instituição.
Definição de meta comercial para crédito e projeção de passivos com modelo ARIMA
Authors: BANDEIRA Carlos Eduardo , VIALI Lorí
Published: December 2018

O processo de definição de metas comerciais em instituições financeiras é extremamente particular. Durante seu processo de construção, cada empresa opta por uma opção que maximizará seus resultados e será condizente com sua capacidade e alcance operacionais. Neste sentido, este artigo busca resgatar o passado recente através da análise de séries temporais, valendo-se do modelo paramétrico ARIMA como ferramenta de apoio à tomada de decisão.
Dados dos clientes: uma troca de valor entre empresa e cliente no setor bancário
Authors: ZINN Felipe , JOAS Léo Fernando Krás
Published: December 2018

O crescimento das tecnologias digitais nos últimos anos impulsionou o desenvolvimento de produtos e dispositivos conectados à internet e possibilitou às empresas coletarem cada vez mais dados a respeito de seus clientes. Essa evolução tecnológica permite também que as empresas coletem dados que outrora eram de difícil acesso e reflete em um valioso banco de dados que permite segmentar ou criar novos produtos, aprimorar aqueles já existentes, promover comunicações direcionadas e até reduzir custos com serviços não utilizados. Nesse cenário, o Marketing de Relacionamento apoia-se no Marketing com Bancos de Dados para analisar grandes quantidades de dados a respeito dos clientes sobre preferências e hábitos de consumo, sendo capaz de identificar padrões de consumo, perfis de relacionamento com o cliente e adaptar produtos e serviços para atender diferentes grupos de consumidores. O presente estudo buscou avaliar a percepção do consumidor gaúcho em relação à coleta de seus dados pelas instituições financeiras e os benefícios esperados pelo cliente como troca de valor pelos dados coletados. Motivada pela escassez do tema na literatura nacional e por pesquisas globais publicadas no último ano, a pesquisa identificou que os clientes gaúchos acenam confiança e disposição em compartilhar seus dados com as instituições financeiras, no entanto, não conseguem enxergar um retorno por parte das empresas. Os resultados por ora obtidos contribuem para a disseminação do tema no meio acadêmico e podem ser utilizados para auxiliar gestores na busca pelos dados de seus clientes.
Retos del milenio: la pobreza extrema y el hambre, una reflexión
Authors: Eslava-Eljaiek Pedro
Published: December 2018

A medida que la población mundial crece, los desafíos para suplir las necesidades básicas de una población de más de 7,500 millones de habitantes cobran importancia, sobre todo en aspectos que fueron formulados como retos del milenio por las Naciones Unidas (ONU, 2000) como la disminución de la pobreza extrema y del hambre. A pesar de que el informe de ese mismo organismo señala que en el 2015 esos indicadores se redujeron a más de la mitad, pues cayeron de 1,900 millones en 1990 a 836 millones en 2015 (ONU, 2015), el desafío aún persiste, puesto que las proyecciones de la ONU señalan que en 2020 la población mundial alcanzará los 7,7 mil millones y en 2100 la Tierra tendrá 11,2 mil millones de habitantes; los países en desarrollo fueron los de mayor crecimiento (UNFPA, 2011). Lo anterior indica que los requerimientos proteínicos y otros nutrientes esenciales para el sustento de esa población creciente deben derivarse de fuentes diversas a las del sector agropecuario.
Diagnóstico clínico de monogeneos en alevinos de piscicultura intensiva en Arauca
Authors: Cala Delgado Daniel Leonardo , Álvarez Rubio Norquis Caled , Muñoz Rodríguez Fabián Andrés , Blanco Torres Carlos Alberto , Yunis Aguinaga Jefferson
Published: December 2018

Dentro de las enfermedades biológicas en la piscicultura, se encuentran las causadas por parásitos, principalmente por la clase monogenea, que provocan perdidas en la tasa de crecimiento y altas mortalidades, representando grandes pérdidas económicas en la acuicultura. Se reportó el diagnóstico clínico de parásitos monogeneos en peces producidos bajo sistemas intensivos, implementando tecnología biofloc (BFT) en dos municipios del Departamento de Arauca. El primer caso se dio en la Asociación Piscícola el Vergel, municipio de Arauquita, en alevinos de tilapia roja (Oreochromis spp.). En el municipio de Arauca, en la Granja Experimental Picure (GEP), se presentó la segunda infestación parasitaria en alevinos de yamú (Brycon siebenthalae). En los dos casos, los parámetros de calidad físico-químicas de agua fueron evaluados con equipos y metodologías establecidas, la evaluación macro y microscópica de los peces fueron realizadas en el laboratorio de especies dulce acuícolas de la Universidad Cooperativa de Colombia sede Arauca. Los parámetros de calidad de agua se encontraron en los rangos ideales para la producción de peces, el único valor por debajo de lo recomendado fueron los sólidos decantables. Las lesiones macroscópicas encontradas fueron exoftalmia, ascitis, hemorragias, aletas y piel erosionada, en la evaluación microscópica, se observaron microorganismos parasitarios y por características morfológicas se logró establecer la presencia de monogeneos. Se instauro tratamiento con sal blanca en dosis de 3 g/l de agua, se realizaron cambios del 50 % del volumen total con agua desinfectada tres días antes usando formol a razón de 10 ml/l de agua. La mortalidad fue del 95 % de la población total de tilapia roja y el 100% de los alevinos de yamú. La desinfección del agua y alevinos antes de la siembra es lo más recomendable para evitar problemas ictiopatológicos
Ensuring an efficient transportation infrastructure security system by means of solutions that enable detection of intrusions into protected areas
Authors: Kuzmina N. A.
Published: December 2018

Due to the nature of its operations, the transportation industry in itself is a potential source of danger. In case of unlawful aggressive intrusions the danger becomes real and fraught with grave consequences. The statistics of the last 10 to 15 years show that 50 to 70% of accomplished terrorist attacks were associated with transportation. Individual measures cannot ensure transportation security. The problem must be approached comprehensively and systemically. Transportation security greatly contributes to the national security of the Russian Federation. The Federal Law of February 9, 2007 no. 16-FZ On transportation security, for the first time in Russian practice, raised the question of securing the entire transportation industry of the Russian Federation, established the legal foundations of the activities related to the protection of transportation infrastructure and vehicles against acts of unlawful interference, including those of terrorist nature. For the first time, a single systemic approach to anti-terrorist protection is provided for all means of transportation. The transportation industry is quite vulnerable to terrorist attacks. We are talking about vehicles, transportation lines, stations, vehicles carrying dangerous loads. The vulnerability of transportation is due to the possibility of damage to signalling, automation and communication assets, whose protection is complicated due to the scale and extent of Russia’s railways. Despite the problems and objective difficulties related to the legislation in the area of transportation security, the workers of the Russian railway industry make their best effort to ensure protection of transportation infrastructure and vehicles against acts of unlawful interference. Promptly reacting to other challenges and threats, they ensure reliable operation of the transportation industry, thus preserving the peace and safety of our citizens. This paper examines matters related to ensuring efficient safety of transportation infrastructure. A significant emphasis is placed on the systems that enable detection of intrusions into protected areas of a facility.
Cooperativismo: A Escolha Pelo Coletivo
Authors: Nespolo Nelsa Inês Fabian
Published: December 2018

O texto aborda a iniciativas de ações do cooperativismo, suas práticas e contradições. Aponta o surgimento de outras formas de organização coletiva, definida como economia social e solidaria, com um resgate forte de princípios de coletividade e de democracia interna, e especialmente para enfrentar as diversas situações de desemprego e sobretudo de falta de perspectivas postos de trabalho.
The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets
Authors: Buckley Benjamin J. , Ali Umar , Kelso Michael J. , Ranson Marie
Published: December 2018

Rheumatoid arthritis (RA) is a chronic and progressive inflammatory disease characterized in its early stages by synovial hyperplasia and inflammatory cell infiltration and later by irreversible joint tissue destruction. The plasminogen activation system (PAS) is associated with a wide range of physiological and pathophysiological states involving fibrinolysis, inflammation and tissue remodeling. Various components of the PAS are implicated in the pathophysiology of RA. Urokinase plasminogen activator (uPA) in particular is a pro-inflammatory mediator that appears to play an important role in the bone and cartilage destruction associated with RA. Clinical studies have shown that uPA and its receptor uPAR are overexpressed in synovia of patients with rheumatoid arthritis. Further, genetic knockdown and antibody-mediated neutralization of uPA have been shown to be protective against induction or progression of arthritis in animal models. The pro-arthritic role of uPA is differentiated from its haemodynamic counterpart, tissue plasminogen activator (tPA), which appears to play a protective role in RA animal models. This review summarises available evidence supporting the PAS as a critical determinant of RA pathogenesis and highlights opportunities for the development of novel uPAS-targeting therapeutics.
Gender Differences in Atrial Fibrillation: A Review of Epidemiology, Management, and Outcomes
Authors: Westerman Stacy , Wenger Nanette
Published: December 2018

Atrial fibrillation is the most common sustained cardiac arrhythmia. The scope and impact of atrial fibrillation are wide; it can affect cardiac function, functional status, and quality of life, and it confers a stroke risk. There are sex differences in atrial fibrillation across the scope of the disease process, from epidemiology and causative mechanisms to management and outcomes. The approach to management of atrial fibrillation differs between women and men, and there are sex differences in response to medical therapy and catheter ablation. There are many gaps in our knowledge of the gender differences in atrial fibrillation, and many opportunities for future research.
Antifungal activity in vitro of Sapranthus microcarpus (Annonaceae) against phytopathogens
Authors: De-la-Cruz-Chacón Iván , López-Fernández Nora Yazmin , Riley-Saldaña Christian Anabí , Castro Moreno Marisol , González-Esquinca Alma Rosa
Published: December 2018

Background and Aims: The phytochemistry study of Annonaceae has intensified in the last decades due to the discovery of secondary metabolites with antimicrobial activities. The inhibitory activities of extracts and compounds from these species for phytopathogens are less known. The antifungal activity of Sapranthus microcarpus was determined in vitro against six fungal pathogens of important crops.Methods: Hexane, methanol, and alkaloid extracts of the leaves and root and stem bark of S. microcarpus were evaluated to determine whether they could inhibit the mycelial growth of the phytopathogens. The combined activity of the most active extracts for each phytopathogen was also determined. The alkaloid liriodenine was isolated and identified as an antifungal principle.Key results: All extracts inhibited the growth of the six phytopathogens to some extent. The root bark alkaloid extract showed the highest activity. Fusarium oxysporum f. sp. lycopersici and Curvularia lunata were the most sensitive phytopathogens. Liriodenine was active against all the plant pathogens (minimum inhibitory concentrations of 125-500 nmol ml-1).Conclusions: Sapranthus microcarpus is a native natural resource with great phytochemical potential.
Evaluasi Peraturan Pelayanan Perpustakaan di Perpustakaan Fakultas Ekonomika dan Bisnis UGM
Authors: Maryatun Maryatun
Published: December 2018

Purpose –The purpose of this study was to identify the reasons for due date book returns, borrowers' attitude when exposed to fines, library efforts to minimize fines and evaluate the effectiveness of fines in the library. Design/methodology/approach – This study used descriptive quantitative and qualitative approach. It was conducted at the Library of the Faculty of Economics and Business, Universitas Gadjah Mada. Samples were purposively selected, involving undergraduate and postgraduate students batch 2011, 2012 and 2013 that never got fines and were still active. Findings – Borrowers had some reasons for overdue book returns, such as they forgot renewing the book, the book was booked by another user, they forgot the due date, they had no class to attend, had not finished reading, borrowed in short period of time, as well as other reasons, such as illness, a friend borrowed the book. So the term of the loan for 5 days was considered insufficient for them to read the books. Borrowers had to pay fines directly. If they were not yet able to pay the fines then they would not borrow books. Borrowers knew that overdue books would put other users at a disadvantage. Most of borrowers considered the fine to pay as much as Rp5,000.00 /day/book was high. But a few regarded it low. Borrowers considered that blocking the system was not effective for those who were late paying fines. The most effective effort that could be done in order that the borrower returned the books on time was providing online renewal system.
Pengaruh Tunjangan Fungsional Pustakawan dan Batas Usia Pensiun yang lebih tinggi Terhadap Motivasi Petugas Perpustakaan di Lingkungan UGM untuk menjadi Pustakawan
Authors: Ismulyana Ismulyana
Published: December 2018

Penelitian ini dilatarbelakangi ....
Konsep Perpustakaan, Sikap Pustakawan, dan Book Vandalism dalam Film 'Mr. Bean' Episode 'The Library'
Authors: Mafar Fiqru
Published: December 2018

Film merupakan ...
Ruang produktif dan ruang leisure: bagian dari praktik konsumsi ruang Perpustakaan Pusat Universitas Gadjah Mada oleh pemustaka digital natives
Authors: Fatmawati Endang , Udasmoro Wening , Noviani Ratna
Published: December 2018

Introduction. The practice of library space consumption is very important to be elaborated by using cultural and media perspective, becaus it  elaborates on the problem of why digital native users interpret of space. This article is part of a dissertation research, which describes social practices and space representation by digital native users at UGM library.Data Collection Method. It is a qualitative research with participant observation, interviews, and supporting documentation, involving six informants selected purposively. Analysis Data. Ethnographic approach is carried out by paying attention to the meaning of the actions of the events that occur in digital native users. Results & Discussions. The results showed that UGM library space was used as productive and non-productive space. As productive space means that digital native users leveraged teh space for learning or other activities related to their study. Meanwhile, non-productive space refers to space to spend their leisure activities. The result showed that digital native users in leveraging the space did not correspond to the initial function of the space. There was inconsistency with the representations of space that was originally designed by the UGM library. Digital natives had their own way of leveraging the library space.Conclusion. There are other motivation how digital native users leveraging the library space. In representational space, digital native users have their own interests. Further research should discuss more specifically in revealing reasons of space use from another theories or perspectives.
PREFERENSI PEMUSTAKA DALAM MENYUSUN TUGAS AKHlR (SKRIPSl/ TESIS/DISERTASI) MENGGUNAKAAN SUMBER INFORMASI DATABASE ONLINE
Authors: Suciati Uminurida , Nurhayati Nurhayati , Widayati Widayati
Published: December 2018

The phenomena that appear in the library as an information center, there are twt all of information sources are available in rhe library. It indicates that user has a special consideration ro preparing the theses, and dissertation using the infonnation sources by internet in the Library of the Faculty of Philosophy of Gadjalt Mada University.The purpose of rite research is  analyze rite attributes as a major preferencefor the users who is writing the thesis and dissertation using internet information sources. The attribute that is used in research is the ease factor ro find the information, accessibility, availability of rite library collections. librarian behavior and user behavior.The data thor is used in this research is the primary  data that fouaded  byquestionnaire of respondents who are writing the thesis and dissertation in the library of the Faculty of Philosophy of Gadjah Mada University between 2005 to 2010 academic years . The instmmem are used in this research using SPSS to get the variables that is considered writing thesis and dissertation as well as tofi nd the most coveted combi110tion for the user looking for information source from online diltabases.The result  of the research show that the user references of the informationsourcesfrom onli11e databases however the collections that are available in print in the librtuy of the Faculty of Philosophy of Gadiah Mada University are still needed. Based on the demographic of respondents, the most user who come in the library qf the Faculty of Philosophy of Gadjah Mada University is man in bachelor degree with the rate is 50,8%, 72,9 % are the bachelor degree respondents In productive age between 21-30 years old. and the most respondents is bachelor degree (Sf ) is 55%,While the use of internet is 3-5 hour a day, the use of online darabases as references in write rhe thesis mtd dissertation is 83.1 %. The research show that the users who access of the information sources using online databases in the library of the Faculty of Philosophy of Gadjah Mada University to writes the thesis mul dissertation is more than the users who looks for print reforences in the Library of the Faculty of Philosophy of Gadjah Mada University to writes the thesis and dissertation. The t«ers choose the online databases as a means of accessing i'![ormation because of low cost, the information is up dare, and complete, it can used to shore the in.fonnarion, and easy to use depend use prim collection in the library.
Persepsi Staf Tentang Pengaruh PemberdayaanSumber Daya Manusia, Kompensasi , Dan Lingkungan Kerja Fisik, Terhadap Prestasi Kerja Sumber Daya Manusia pada Perpustakaan Institut Seni Indonesia Yogyakarta
Authors: Bandono Bandono
Published: December 2018

Abstrak
Analisis Tingkat Kepuasan Pemustaka terhadap Kepuasan Layanan pada Perpustakaan Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Gadjah Mada
Authors: Harmoko Sapto
Published: December 2018

This study aimed to find out: User Satisfaction on the Quality of Service of The Library Faculty of  Mathematics and Natural Sciences, Gadjah Mada University Library. Data were collected by using questionnaires as the main method, documentation and interview as a complementary method. Population taken are all users MIPA UGM Faculty Library in April 2010. Samples taken as many as 100 respondents using incidental sampling technique. The analysis used are Qualitative Analysis and Quantitative Descriptive Analysis. Based on the Quantitative Descriptive Analysis, the results obtained can be summarized as follows: The score of assessment criteria based on the average value of 3.64 overall results thus obtained can be categorized that user satisfaction on the quality of library services at the Faculty of Science, GMU is good. Of the 24 indicators under consideration are translated into five sub-variables, namely: tangible, reliability, Responsiveness, Assurance, Empathy. Of the five variables into the user satisfaction in choosing a service to the Faculty of Science, Gadjah Mada University Library which became the main consideration for the variable of tangible, the average value user satisfaction is 3.77, so based on the average value is good. For the dimensions of reliability, the average value user satisfaction is 3.59, so based on the average value is good. For dimensions of responsiveness, the average value user satisfaction is 3.65, so based on the average value is good. For security dimension, the average value user satisfaction is 3.64, so based on the average value is good. For the dimensions of empathy, the average user satisfaction is 3.58, so based On the average value is good.
TEMU KBMBALI INFORMASI BIBLIOGRAFI DENGAN BAHASA ALAMI PADA FIELD JUDUL DAN SUBJEK (Studi Efektivitas katalog Induk Terpasang Perpustakaan UGM)
Authors: Saptari Janu , Purwono Purwono
Published: December 2018

Abtrak
Subjek Artikel Dipesan dan Kesesuaiannya Dengan Klaster Riset
Authors: Maryono Maryono
Published: December 2018

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Evaluasi Kualitas Layanan Perpustakaan FEB Undip Berdasarkan Harapan dan Persepsi Pemustaka dengan Metode LibQUAL
Authors: Fatmawati Endang
Published: December 2018

Library quality services evaluation is an important activity for acadernic libraries. This research is to evaluate service quality library at Economica and Business Faculty of Diponegoro University base on desired and perceived of users with LibQUAL methods. The aims to measurement library service qualityfrom desired and perceived users, and to know service library dimensions don't fullfill desired and perceived users. Quality is defined as "capability" - how good is the library? LibQUAL is effective total survey market to contact research in library to evaluation library quality service. Assessment based on perceived, minimum expectations, and desired. LibQUAL method gives users a chance to tell library where library services need improvement so it can respond to and better manage their expectations. Dimensions in LibQUAL consist of: Service Affect (SA), Library as Place (LP), Personal Control (PC), and Information Access (IA). Population is taken from Diploma III Program; Regular I, and Reguler II students, year 2009/2010 with proporsional stratified random sampling and the total sample is 81 respondents. This research used quantitative method with sumey and evaluation research. Users were asked to complete a questionnaire. Analyze its to know average perceived, minimum, and desired. The distance of the perceived score from the minimum score (P - M) creates a adequacy gap, and from the desired score (P – I) creates a superiority gap. The result shows that library service quality is fuffill minimum expectation of users. This means users had "enough satisfaction" with service perceived.