bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Komunikasi Pemasaran Jamu Tradisional di Era Teknologi Digitalisasi 4.0
Authors: Daud Rosy Febriani , Novrimansyah Eko Abadi
Published: September 2022

Jamu tradisional sudah tidak asing lagi bagi kita sebagian masyarakat di Indonesia. Jamu tradisional juga memiliki manfaat yang penting dalam kehidupan masyarakat, yakni sebagai warisan budaya lokal dalam bidang kesehatan. Beberapa dekade terakhir, telah terjadi perkembangan teknologi informasi dan internet yang sangat pesat yang mendorong terjadinya revolusi industri 4.0. Perkembangan teknologi ini tidak hanya sekadar membuka interaksi secara luas namun juga mendisrupsi berbagai bidang kehidupan manusia. Fenomena disrupsi memberikan dampak perubahan yang besar dalam berbagai bidang terutama strategi komunikasi pemasaran jamu tradisional. Dalam penelitian ini, peneliti tertarik untuk mengangkat penelitian tentang strategi pemasaran jamu tradisional di era teknologi digitalisasi 4.0. Penelitian ini merupakan penelitian deskriptif kualitatif dengan metode studi kasus. Penelitian deskriptif kualitatif ini mengungkapkan bagaimana strategi komunikasi pemasaran jamu tradisional di era teknologi digitalisasi 4.0. Peneliti memfokuskan penelitian pada strategi komunikasi pemasaran obat tradisional di era tekologi digitalisasi 4.0. dalam meningkatkan penjualan. Peneliti menggunakan teknik sampling purposive dengan mengambil tiga orang informan. Adapun teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan studi dokumentasi.
Pengaruh Budaya Organisasi Terhadap Tata Kelola Perusahaan pada Rumah Sakit di Jabodetabek
Authors: Yosefin  , Rosalina Anna
Published: September 2022

Penelitian ini dilakukan untuk mengetahui seberapa jauh budaya organisasi pada rumah sakit mempengaruhi penerapan good corporate governance pada rumah sakit secara signifikan. Penelitian ini juga ingin mengetahui seberapa jauh tipe kepemilikan mempengaruhi budaya organisasi secara signifikan. Variabel independen yang digunakan dalam penelitian ini adalah budaya organisasi pada rumah sakit yang dijabarkan dalam inovasi, detail, orientasi hasil, orientasi orang, orientasi tim, keagresifan, dan kemantapan. Variabel dependen dalam penelitian ini adalah corporate governance yang dijabarkan dalam fairness, transparancy, accountability, dan responsibility. Penelitian ini menggunakan data primer dari kuisioner yang diberikan kepada 150 responden pada tiga rumah sakit. Setiap rumah sakit diambil sampel 50 responden. Pada setiap rumah sakit, kuisioner kuisioner tersebut diberikan kepada 3 orang manajemen, 7 orang dokter, 32 orang perawat, dan 8 orang staf administrasi. Ketiga rumah sakit yang diteliti adalah RSPAD Gatot Subroto, RSAL Mintoarjo, dan RS St. Carolus. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling. Hipotesis yang digunakan dalam penelitian ini ada dua hipotesis. Uji yang digunakan untuk mengetahui hasil dari penelitian ini adalah statistik deskriptif, uji validitas dan reabilitas, uji kesesuaian model, dan uji hipotesis. Data diproses dan dianalisis menggunakan regresi berganda untuk semua variabel. Hasil dari uji – uji yang dilakukan menunjukkan bahwa budaya organisasi pada rumah sakit tidak mempengaruhi penerapan corporate governance pada rumah sakit secara signifikan. Dan, tipe kepemilikan tidak mempengaruhi budaya organisasi secara signifikan.
Perancangan Sign System SMK Tritech Informatika
Authors: Nasir Reza Asif , Prayogi Rendy
Published: September 2022

Sign system memiliki peran sangat penting dalam penyampaian informasi masa kini, sign system adalah sebuah papan penanda yang mengarahkan dan memberikan sebuah informasi kepada pengunjung dan memberikan kesan keindahan bagi lingkungan. SMK Tritech Informatika adalah sekolah yang berdiri sejak tahun 2010 dan memiliki berbagai pilihan jurusan IT dan mempunyai misi untuk melahirkan generasi yang handal dalam bidang IPTEK, IMTAQ, dan berjiwa kebangsaan. SMK Tritech Informatika belum mempunyai sign system yang memiliki ciri khas yang menunjukkan kesan IT di sekolah tersebut. Konsep perancangan sign system SMK Tritech Informatika adalah menonjolkan kesan teknologi dan IT agar menggambarkan ciri khas SMK Tritech Informatika.
Pengaruh Kinerja Keuangan Terhadap Return Saham pada BRIlife
Authors: Sari Dona Putri Arum , Hartono Arif , Sayidatul Nur
Published: September 2022

Tujuan dari penelitian ini ialah untuk mengetahui apakah Current Ratio (CR), Debt to Equity Ratio (DER), dan Total Asset Turn Over (TATO) berpengaruh terhadap return saham, baik secara individual maupun kombinasi. Catatan keuangan BRI Life pada tahun tersebut dijadikan sebagai populasi penelitian. [Rujukan?] [Rujukan?] Lima laporan keuangan periode 2014-2021 yang telah diaudit secara keseluruhan pada kuartal keempat setiap tahun berikut: 2014, 2015, 2016, 2017, 2018, 2019, 2020, dan 2021 Dalam bentuk neraca, laporan laba rugi, laporan arus kas, dan catatan atas laporan keuangan, laporan keuangan mencakup semua hal berikut. Dalam penelitian khusus ini, proses pengumpulan data menggunakan metode sampel jenuh. Sampel yang diperoleh sesuai dengan kriteria yang ditentukan oleh sebanyak tiga puluh dua perusahaan yang berbeda Teknik analisis yang digunakan ialah deskriptif kuantitatif, dan program statistik yang digunakan ialah SPSS Versi 26. Temuan penelitian ini mengungkapkan bahwa rasio lancar memiliki pengaruh terhadap return saham yang substansial dan menguntungkan, bertentangan dengan hipotesis awal yang diuji. Hal ini menunjukkan bahwa tinggi rendahnya current ratio (CR) keduanya berdampak pada return perusahaan. Bukti yang disajikan dalam penelitian ini mendukung hipotesis kedua, yang menegaskan bahwa Debt to Equity Ratio (DER) memiliki dampak yang cukup besar, baik secara positif maupun signifikan, terhadap return saham. Temuan eksperimen yang dirancang untuk menguji hipotesis ketiga menunjukkan bahwa Total Asset Turnover (TATO) memiliki pengaruh yang berarti yaitu terhadap keuntungan return saham. Hasil penelitian menunjukkan, berdasarkan hasil pengujian simultan, bahwa variabel independen (pengaruh Current Ratio (CR), Debt To Equity Ratio (DER), dan Total Asset Turn Over (TATO)) memiliki pengaruh yang signifikan dan pengaruh simultan terhadap variabel yang diteliti yaitu variabel terikatnya (return saham). Berdasarkan Koefisien Determinasi dan hasil penelitian, variabel bebas yang digunakan dalam penelitian memberikan kontribusi sebesar 53,4%, terlihat dari R square, sedangkan sisanya 46,6% dipengaruhi oleh faktor-faktor yang tidak termasuk dalam variabel penelitian.
Research on the Watchtower Architecture of Overseas Chinese Hometown in Tangjiawan, Zhuhai — Taking Huitong South Watchtowers and Huitong North Watchtowers as Examples
Authors: Junxin Song
Published: September 2022

The architectural design of the watchtowers in the hometown of overseas Chinese in Tangjiawan was affected by social environmental factors and historical factors, which well adapted to the climate of the Tangjiawan area and formed a unique architectural style, representing the characteristics of history and culture at that time. This paper analyzes the architectural function, use function and architectural form of Huitong South watchtowers and Huitong North watchtowers, and preliminarily discusses the regional characteristics of watchtowers in the Tangjiawan hometown of overseas Chinese.
Prediksi Financial Distress Pada Perusahaan Sektor Property dan Real Estate Yang Terdaftar di Bursa Efek Indonesia Periode 2017-2020
Authors: Hanifah Martini  , Setyawasih Rianti
Published: September 2022

This study aims to prove the ability of financial rations in measuring financial distress. The financial ratios used in this study are return on assets, current ratio, debt to assets ratio, and total assets turnover in property and real estate companies listed on the Indonesia Stock Exchange (IDX) period 2017-2020. The research sample was determined by purposive sampling method and Z’-Score with  < 1,23 that obtained 66 data. The data used in the form of secondary data from www.idx.co.id. The method used is multiple linear regression analysis. According to the results of research that has been done, the variabels of are ROA, CR, and TATO had a significant adverse effect, while variabel DAR had a significant positive effect on financial distress
Analisis Kadar Zat Besi (Fe) dan Vitamin C pada Ekstrak Buah Kurma (Phoenix Dactylifera L.)
Authors: Siti Zamilatul Azkiyah , Rahimah Hayatul
Published: September 2022

Buah kurma merupakan salah satu buah yang disebutkan dalam Al-Qur’an maupun beberapa Hadis. Salah satu ayat tentang buah kurna yakni disebutkan dalam Q.S An-Nahl ayat 11 yang artinya:”Dia menumbuhkan bagi kamu dengan air hujan itu tanam-tanaman; zaitun, kurma, anggur dan segala macam buah-buahan. Sesungguhnya pada yang demikian itu benar-benar ada tanda (kekuasaan Allah) bagi kaum yang memikirkan.”Ayat tersebut merupakan petunjuk bagi manusia bahwa buah kurma memiliki manfaat bagi umat manusia. salah satunya yakni ekstrak buah kurma sebagai antioksidan. Dengan demikina, dilakukanlah penelitian ini dengan metode penelitian eksperimental untuk mengetahui kadar besi dan vitamin C pada ekstrak buah kurma.Prosedur penelitian ini yakni ekstraksi dengan preparasi berupa pembuatan simplisia buah kurma dengan metode ekstraksi maserasi menggunakan pelarut etanol 96%. Selanjutnya dilakukan pemisahan menggunakan rotary evaporator dengan suhu 50oC dan memaksimalkan ekstrak kental menggunakan oven dengan suhu 50oC dan penyimpanan dalam desikator.Uji skrining fitokimia menggunakan uji flavonoid, uji fenolik, saponin, terpenoid, dan alkaloid. Uji kadar besi dan vitamin C dilakukan secara kuantitatif menggunakan Spektrofotometer serapan atom untuk uji kadar besi dan Spektrofotometer UV-Vis untuk uji kadar vitamin C. Hasil kadar besi (Fe) rata-rata pada ekstrak buah kurma yakni 0,1392 ppm dan hasil kadar vitamin C pada ekstrak buah kurma yakni 9,696 mg/mL.
Sosialisasi Pengisian Lembar Catatan Perkembangan Pasien Terintegrasi pada Perawat
Authors: Rahmadiliyani Nina , Wardhina Faizah
Published: September 2022

Rumah sakit adalah suatu institusi pelayanan kesehatan yang kompleks, padat pakar, dan padat modal. Kompleksitas ini muncul karna pelayanan rumah sakit menyangkut berbagai fungsi pelayanan, pendididikan penelitian, serta mencakup berbagai tingkatan maupun jenis disiplin, agar rumah sakit mampu melaksanaakan fungsi yang professional baik di bidang teknis medis maupun administrasi kesehatan. Catatan perkembangan pasien terintegrasi merupakan catatan pendokumentasian yang dilakukan oleh tenaga kesehatan untuk melakukan koordinasi atau kolaborasi antar tenaga kesehatan dalam melakukan pendokumentasian pelayanan kesehatan pada pasien. Pelaksanaan program pengabdian ini dilakukan melalui sosialisasi dengan memberikan materi berupa pengisian lembar Catatan perkembangan pasien terintegrasi. Evaluasi pelaksanaan program dilakukan dengan terlebih dahulu memberikan pertanyaan kepada responden sebelum pelaksanaan sosialisasi (pretest) dan kembali memberikan pertanyaan lagi setelah pelaksanaan sosialisasi (posttest). Berdasarkan hasil dari kegiatan pengabdian kepada masyarakat dapat disimpulkan bahwa kegiatan sosialisasi ini dapat meningkatkan pengetahuan perawat mengenai ke catatan perkembangan pasien terintegrasi.
Sosialisasi Implementasi Ekonomi Islam dalam Praktik di Dunia Kerja pada Mahasiswa Baru STEI SEBI Depok
Authors: Arumingtyas Fida , Megaster Tekni , Mardian Sepky
Published: September 2022

Pelaksanaan Pengabdian Kepada Masyarakat (PKM) yang dilaksanakan di Sekolah Tinggi Ekonomi Islam SEBI, Sawangan, Depok, dilatarbelakangi oleh kurangnya pengetahuan dan pemahaman mahasiswa baru STEI SEBI mengenai implementasi ekonomi Islam di dunia kerja. Metode PKM dilaksanakan melalui sosialisasi dengan pendekatan talkshow dengan tujuan agar sosialisasi tersebut mampu diterima oleh mahasiswa baru yang merupakan generasi milenial. Hasil sosialisasi menunjukkan adanya peningkatan menunjukkan adanya peningkatan pengetahuan dan pemahaman mahasiswa baru STEI SEBI terhadap praktik ekonomi Islam di dunia kerja.
Pelatihan Manajemen Usaha dalam Meningkatkan Usaha UMKM Kuliner
Authors: Nasution Jafar , Hardana Ali , Damisa Arti , Rasyid Arbanur
Published: September 2022

Jumlah Usaha Mikro Kecil serta Menengah (UMKM) ialah bagian yang besar dari pelaksana ekonomi secara totalitas. Tetapi pertumbuhan UMKM yang berkaitan dengan kemajuan teknologi masih belum sesuai harapan. Proporsi UMKM yang memakai penjualan online masih rendah. Perihal itu diakibatkan oleh masih banyak UMKM yang belum memahami secara teknis tatacara penjualan online. Tujuan dari kegiatan ini adalah untuk mengembangkan keahlian UMKM dalam manajemen secara universal, pemasaran digital dan pencatatan keuangan. Pengembangan dan peningkatan yang dilakukan berupa pengembangan ketrampilan pembuatan perencanaan pemasaran, pemasaran digital dan pemahaman pencatatan keuangan sehingga dapat berguna dalam mengembangkan usaha yang akan dijalankan di kemudian hari. Partisipan pelatihan sebanyak 34 usaha mikro, sebagian besar merupakan usaha kuliner yang diberi pelatihan manajemen yang mereka butuhkan. Hasil yang diperoleh dari aktivitas ini merupakan terjadinya mitra binaan kuliner yang lebih maju dalam pengelolaan serta penjualan produk secara online.
Pengembangan Skala Usaha Bumdes Tritunggal Mandiri melalui Pemanfaatan Potensi Desa Martadah Baru Kabupaten Tanah Laut
Authors: Risal Semuel , Irawanto  , Misransyah  , Saputra Riky Welli , Asmawatiy Cici , Priono Singgih
Published: September 2022

Badan Usaha Milik Desa (BUMDes) adalah sebuah lembaga usaha desa yang bertujuan untuk memperkuat perekonomian desa dan dibentuk berdasarkan kebutuhan dan potensi sumberdaya yang ada di desa. Minimnya kontribusi BUMDes dalam pertumbuhan ekonomi disebabkan karena terbatasnya kualitas SDM, tata kelola BUMDes, hingga minimnya pemahaman potensi desa yang dimiliki sebagai basis usaha BUMDes. Tujuan pengabdian ini adalah melakukan pengembangan kapasitas pengelolaan BUMDes yang diawali dengan melakukan riset dan pemetaan secara mendalam sehingga BUMDes dikembangkan sesuai dengan potensi lokal, memberikan pengetahuan dan pemahaman bagi para stakeholder desa tentang BUMDes yang sesuai dengan kebutuhan dan potensi yang dimiliki oleh desa, serta mengidentifikasi potensi yang dimiliki desa dan merumuskan bentuk-bentuk usaha yang dapat dilakukan melalui BUMDes serta menginventarisasi rancangan usaha (business plan) prioritas rintisan BUMDes yang berpeluang untuk ditindaklanjuti sebagai usaha BUMDes di desa Martadah Baru. Metode pelaksanaan kegiatan ini adalah dengan melakukan survey, diskusi (FGD) dalam forum pertemuan desa dan perumusan rencana (kerja) usaha. Selain dapat dapat menemukan potensi usaha, meningkatkan pengetahuan dan pemahaman stakeholder tentang pentingnya peran BUMDes, hasil kegiatan ini dapat mengidentifikasi bentuk usaha BUMDes yang sesuai dengan potensi unggulan desa dan merumuskan prioritas rencana bisnis BUMDes, dan merekomendasikan implementasi ditindaklanj untuk usaha ekonomi produktif yang dapat membantu pengembangan ekonomi ekonomi masyarakat desa.
Pemberdayaan Kader Posyandu dalam Sistem Manajemen Pelayanan Kesehatan Ibu Nifas Masa Pandemi Covid-19 di Puskesmas Waisai Kabupaten Raja Ampat
Authors: Sunaeni  , Ismail Zaenab
Published: September 2022

Pandemi Covid-19 berdampak menurunnya layanan Puskesmas, termasuk juga posyandu. Kunjungan akseptor KB dan nifas hanya berkisar 10,9 % dari 9296 orang. Diperlukan kerjasama dari berbagai pihak agar pelayanan kesehatan bagi ibu nifas diakses dengan mudah, meskipun dalam masa pembatasan aktifitas. Tujuan pengabdian agar kader posyandu dapat membantu bidan meningkatkan derajat kesehatan ibu nifas  masa pandemi covid-19 melalui sistem manajemen terpadu terintegrasi dengan pelayanan kesehatan. Metode kegiatan berupa pelatihan bagi kader posyandu, meliputi persiapan, pelaksanaan dan evaluasi. Sasaran kegiatan adalah kader posyandu dan bidan. Pengabdian dilakukan di Puskesmas Waisai Kabupaten Raja Ampat. Hasil pengabdian terjadi peningkatan daya saing yang terlihat dari pengetahuan kader 87 % baik, ketrampilan 80 % baik. Diperlukan upaya secara terus menerus berkelanjutan dalam peningkatan ketrampilan kader posyandu.
Kebijakan Pengupahan Mencekik Kesejahteraan Buruh
Authors: Soemali
Published: September 2022

Kebijakan  pemerintah tentang pengupahan menghapuskan upah minimum sektoral provinsi dan/atau kabupaten/kota merupakan bentuk penghilangan hak dan melemahkan kesejahteraan dan ketidakadilan pekerja/buruh  serta tidak  sesuai Pancasila dan Undang-Undang Dasar 1945. Penerapam kebijakan formula baru dalam penyesuaian penetapan besaran nilai upah minimum provinsi dan/atau kabupaten/kota tahun 2022 terbukti hasilnya lebih  rendah dibandingkan dengan kebijakan lama. Kebijakan pengupahan baru bukan meningkatkan kesejahteraan, tetapi justru merampas dan mencekik hak pekerja/buruh dan keluarganya dalam meningkatkan kesejahteraan guna memenuhi kehidupan yang layak.
The Effect of Internal Control System on Financial Accountability of Regional Public Service Agency of Public Health Center (BLUD Puskesmas) During Covid-19 Pandemic
Authors: Suwardi  , Achmad Choerudin  , Widodo Feriyanto
Published: September 2022

This research aims to study the effect of internal control system (SPI) on Financial Accountability of Regional Public Service Agency of Public Health Center (BLUD Puskesmas). The research took place in Karanganyar Regency of Central Java Province, Indonesia. Data of research was collected from all Public Health Centers (Puskesmas) in Regency during pandemic period. The institutional analysis unit consisted of 21 Puskesmas with 125 respondents. The analysis technique used was a multiple regression. Results: (1) information and communication, and monitoring affect positively the financial accountability, and (2) control environment, risk estimation, and controlling activity do not show significant effectThis research aims to study the effect of internal control system (SPI) on Financial Accountability of Regional Public Service Agency of Public Health Center (BLUD Puskesmas). The research took place in Karanganyar Regency of Central Java Province, Indonesia. Data of research was collected from all Public Health Centers (Puskesmas) in Regency during pandemic period. The institutional analysis unit consisted of 21 Puskesmas with 125 respondents. The analysis technique used was a multiple regression. Results: (1) information and communication, and monitoring affect positively the financial accountability, and (2) control environment, risk estimation, and controlling activity do not show significant effect
Studi Kelayakan Target Raihan Suara Partai Demokrat Untuk Pemilihan Legislatif di Dapil 1 Kota Bandung
Authors: Aan Andi Purnama  , Eka Purwanda
Published: September 2022

Penelitian ini bagaimana pemilihan legislatif dan raihan suara Partai Demokrat dan bagaimana studi kelayakan dari target Partai Demokrat itu sendiri, dengan strategi komunikasi yang baik, sosialisasi, Kegiatan yang terselenggara (event) jaringan  Pemerintah Kota, Kecamatan, Kelurahan bahkan hingga pengurus RT-RW secara tidak langsung Caleg Partai Demokrat dapat dikenal dalam masyarakat dan juga sebaliknya masyarakat juga akan mengenal calegnya. Penyampaian misi dan visi Partai Demokrat juga dilakukan caleg dalam setiap kampanye, baik secara terbuka maupun tertutup. Hal tersebut dilakukan untuk mengenalkan Partai Demokrat kepada masyarakat.
Tanggung Jawab Orangtua Dalam Pelaksanaan Pendidikan di Dalam Keluarga Berdasarkan Ulangan 6:4-9
Authors: Martinus Laia  , Vroly R. Wowor  , Wahyu Juli Suryaningsih  , Sedirman Lawolo  , Rosianna Purba
Published: September 2022

Dalam penulisan ini tujuannya adalah menganalisis tanggung jawab orangtua dalam pelaksanaan pendidikan di dalam keluarga berdasarkan Ulangan 6:4-9. Pendidikan sangat penting dilaksanakan dalam keluarga, oleh karena itu orangtualah yang bertanggung jawab untuk melaksanakannya. Pendidikan utama dan terutama dimulai dari keluarga, namun, seringkali ditemukan sebagian orangtua melalaikan tanggung jawabnya dalam melaksanakan pendidikan bagi anaknya, dikarenakan orangtua beranggapan bahwa mendidik anak merupakan tanggung jawab guru di sekolah. Penulisan ini menggunakan pendekatan metode kualitatif deskriptif, dan mengumpulkan data melalui buku-buku, Alkitab, dan literatur seperti jurnal, berbagai dokumen yang mempunyai keterkaitan dengan yang dibahas. Hasilnya, pertama, orangtua bertanggung jawab untuk memperkenalkan Allah yang benar kepada anaknya melalui pendidikan dalam keluarga. Kedua, orangtua bertanggung jawab untuk mendidik anak secara berkesinambungan. Kesimpulannya orangtua bertanggung jawab untuk memperkenalkan Allah yang benar kepada anak melalui pendidikan dalam keluarga serta orangtua bertanggung jawab untuk mendidik anak secara berkesinambungan.
Kontribusi Istri Nelayan Dalam Meningkatkan Pendapatan Keluarga Inti di Desa Muara Wis Kecamatan Muara Wis Kabupaten Kutai Kartanegara
Authors: Rinda Permaisari  , Gusti Haqiqiansyah  , Erwiantono
Published: September 2022

Penelitian ini bertujuan menganalisis konstribusi pendapatan yang diberikan istri nelayan dalam keluarga dan mengetahui faktor apa saja yang mendorong istri nelayan dalam meningkatkan pendapatan keluarga di Desa Muara Wis. Hasil penelitian ini menunjukkan kontribusi pendapatan istri nelayan yang bekerja sebagai pengolah ikan asin sebesar 35,81% (11 orang) dan yang bekerja sebagai pengolah kerupuk ikan adalah 37,86% (9 orang). Dengan deskripsi nilai tersebut berada pada kategori yang rendah dengan rentang kontribusi 20% - 39%. Artinya kontribusi istri masih belum cukup penting untuk membantu meningkatkan pendapatan keluarga nelayan di Desa Muara Wis. Kemudian faktor yang mendorong istri nelayan bekerja guna meningkatkan pendapatan keluarga di Desa Muara Wis adalah adanya pengaruh dari waktu luang yang dapat dilakukan istri nelayan, pendapatan suami yang belum cukup memenuhi kebutuhan keluarga, dan untuk menambah tingkat kesejahteraan keluarga
Cancer cell-derived exosomes as the delivery vehicle of paclitaxel to inhibit cancer cell growth
Authors: Kanchanapally Rajashekhar , Brown Kristen
Published: September 2022

Delivering water-insoluble drugs, such as paclitaxel (PTX), to the tumor site is a challenge. Exosomes are capable of delivering “cargo” to the target site without causing adverse effects, unlike synthetic nanoparticles. Here, we have prepared PTX-loaded exosomes from breast cancer cells. This formulation is further explored for its activity against breast cancer cell lines. Our data indicate that the exosomes are more efficient than free paclitaxel and liposomal paclitaxel in inhibiting the cancer cell growth. The primary reason for this superior activity is determined to be exosomes’ ability to deliver more amount of drug in the cytosol. However, the exact mechanism by which exosomes deliver the drug across the cell membrane still needs to be explored.
Carta Editorial G18 Director
Authors:   Escuela Superior de Ingeniería y Arquitectura Unidad Tecamachalco del Instituto Politécnico Nacional, Cruz Ramírez Luis Carlos
Published: September 2022

La conservación y la restauración del patrimonio arquitectónico es una línea de investigación en desarrollo, del área que actualmente se denomina ciencia del ambiente construido. Aunque la cantidad de aportaciones aumenta cada año, constantemente se identifican nuevos problemas. El número 18 de la revista Gremium (G18), trae las aportaciones de cinco artículos desde la óptica de editores invitados de números anteriores de nuestra revista. Se explora el patrimonio construido desde los siguientes ejes temáticos: prevención de riesgos, espacio público, estética urbana, el cambio de uso, arqueología prehispánica mexicana, sistemas constructivos a base de tierra y la filosofía de la conservación.
Social Realism in Meena Kandasamy’s Novel The Gypsy Goddess
Authors: Dr Ravindra D. Hajare
Published: September 2022

Social realism, as derived from the Marxist ideology, is something which adheres to reality, avoids romantic embellishments, and creates truthful portraits of life that expose human flaws. In it, we find characters with genuine jobs and problems. It records the life of an average farmer or labourer. The novel the Gypsy Goddess by Meena Kandasamy is an indictment of Communism and atrocities inflicted upon untouchable coolies and paddy workers. Mena Kandasamy presents the fictionalized version of the tragedy, portrayed on the documents taken from history and interviews of people who faced that actual incident. The landlords murder a communist leader. After that, the Dalit labourers go on strike, Dalit workers are forced to work back on farms, and those who refuse are assaulted and punished by the police. The democratic demand for justice by the untouchables farmers of Kilenmani, Tamil Nadu, are faced with a terrible series of actions which prove ‘might is right’, and the poor, helpless farmers are only left to suffer and die due to hostile conditions. The novel is a fine narrative of their plight and the traumatic conditions caused by the violence inflicted upon them.   In brief, it is a fictionalized work on social realism. The present paper is a brief study of events that occur in the lives of Dalit, unprivileged paddy workers and their exploitation by so-called Upper Caste or Landlords and their realistic representation.
Existential Crisis in Hardy’s “Tess’s Lament”: Text, Context, and Psychological Praxis
Authors: Dr Dharmendra Kumar Singh
Published: September 2022

Thomas Hardy is the last of the great Victorian novelists. He is known as one of the best English novelists. He is more well-known for his novels than for his poems. Tess of d’Urbervilles: A Pure Woman Faithfully Presented is one of those hallmarking and time-beating novels, he has written. The unique thing annexed to this novel is that he has composed a non-narrative poem expressing Tess’ deep pain and pang over her loss entitled “Tess’s Lament”, which seems to be it's supplementary. It appears that its miniature presents the whole through the part. Existential crisis, usually considered a complicated event, can be seen as the core of psychology, which comprises emotional, cognitive, and behavioural parts. Both in the poem "Tess's Lament" and in Tess's own life, the psychological practice of existential crises plays a key role. Whatever she does, she feels sad, alone, and helpless. It also makes her feel like her life has no meaning or purpose, and it keeps her from interacting with other people, which upsets the emotional, mental, and behavioural parts of her existence and being.
Identifying disease risk hotspots in buffalo meat (Carabeef) value chain
Authors: BARDHAN D , KUMAR S , KUMAR S , KUMAR N , KHAN R , TALUKDER S , MENDIRATTA S K
Published: September 2022

The study was carried out to quantitatively map and analyse buffalo meat value chains in Uttar Pradesh state ofIndia. The chain actors identified were farmers, peri-urban and urban dairies, aggregators, traders/sub-traders,retailers, restaurants/ roadside stalls and export-oriented abattoirs. Mapping exercise shows that aggregators constitutethe main link between farmers and live animal markets and account for 72% of the total flow of buffaloes tolivestock markets. Sub-traders/traders ship the bulk of the flow from markets to abattoirs. Of the total meat produced,87% is shipped directly to importing countries and the rest (12%) to retailers (local and from other districts). Theresults of quantitative value chain mapping along with the risk pathways in the value chain (as identified by theresearch team) were presented to a panel of experts for rating of each risk factor on two dimensions, viz. â€˜likelihoodof risk factor causing unwanted outcomeâ€™(introduction of pathogenic organism) and â€˜impact of unwanted outcomeâ€™(quality deterioration and adverse health implications for consumers of final meat products), each on a three-pointcontinuum (low, medium and high). The ratings were then used to prepare a two-dimensional risk matrix havingtotal of nine cells. The above exercise identified total of seven major disease risk hotspots in buffalo meat valuechain. Overall, this study provided qualitative evidence of importance of adopting value chain approach in diseaserisk mitigation, by identifying structural deficiencies and vulnerabilities.
Fertility response following ablation-induced follicular wave emergence and ovulation induction in anestrous buffaloes
Authors: HONPARKHE MRIGANK , GANDOTRA VINOD KUMAR , BRAR PARKASH SINGH , MALIK ASLOOB AHMED , DADARWAL DINESH , SINGH JASWANT
Published: September 2022

The fertility response following induction of follicular wave emergence by follicle ablation combined withprogesterone based ovulation synchronization in postpartum anestrous buffaloes was assessed. Postpartum anestrousbuffaloes (n=24) with absence of overt estrus signs categorized as treatment group (Group 1; n=15) and controlgroup (Group 2; n=9). Group 1 was subjected to transvaginal ultrasound-guided follicle ablation on a random dayof the estrous cycle (Day=0) and insertion of CIDR. Seven days later, CIDR was removed and prostaglandin F2Î±analogue was given intramuscularly. GnRH analogue was injected on day 9.5 and fixed-time AI was done 12 h and24 h later. Ultrasonography was performed to follow ovarian structures on different occasions and on day 38 postovulationfor detecting pregnancy. Group 2 did not receive any treatment however, estrus detection in this groupwas done daily by bull parading and visual monitoring followed by AI if found in standing estrus. In treatmentgroup, the follicular wave emergence occurred by 24 h following ablation in 60% buffaloes and in 40% remaininganimals by 48 h. The estrus exhibition was 100 % in group 1 versus 22.2 % in group 2. Mean interval from CIDRremoval to ovulation was 81.2Â±3.08 h and from wave emergence to ovulation was 9.92Â±0.18 days. The first servicepregnancy rate in treatment group was higher than control (66.67% vs 22.2%). The induction of follicular waveemergence through ultrasound guided follicle ablation and progesterone based ovulation synchronization can beused to improve pregnancy rates in anestrous buffaloes.
Effect of controlled internal drug release insert on conception rate of repeat breeder cows
Authors: CHANDEL ANSHUL , SINGH MADHUMEET , KUMAR PRAVESH , SHARMA AKSHAY
Published: September 2022

The present study was aimed at improving the conceptionrate in repeat breeder cows (N=43) suffering from functional form of infertility with the use of controlled internal drugrelease device (CIDR) pre- and post-insemination. Repeatbreeder cows were divided into two treatment, i.e. CIDR-I(n=12) and CIDR-II (n=13), and one control group (n=18).The overall conception rate in first and second treatmentgroup, i.e. 58.33 and 61.54%, respectively, were nonsignificantlyhigher as compared to control group (22.22%).In conclusion, CIDR protocols fared better in achievingconception in repeat breeder cows.
Effect of mother contact and voluntary colostrum suckling on growth, health and stress of neonatal buffalo calves
Authors: CHOUDHARY SANJAY , KAMBOJ M L , JAMWAL SHWETAMBRI , PAL PRASANNA , ARORA DEVAN , INGLE VINAYAK , SINGH PAWAN , LATHWAL S S
Published: September 2022

The aim of present study was to investigate the effect of full mother contact and voluntary colostrum suckling on the health, stress and growth performance of neonatal Murrah buffalo calves. For this, two experiments (exp.) were conducted involving exp.1, 24 mother-calf pairs were divided into three equal groups (eight pairs/each group). In no mother contact (NC) group, weaning was allowed immediately after birth. In restricted mother contact (RC) group, restricted contact was allowed twice daily. In fence-line mother contact (FC) group, calves were in full-time mother contact from birth to day (d) 5 and allowed voluntary colostrum suckling and thereafter fence-line contact. In exp.2, another 24 mother-calf pairs were selected and divided into two groups (12 pairs in each group), with the same conditions as the RC and FC groups in exp.1. Average daily gain, total protein and total Ig concentrations differed between different groups in both experiments. Cortisol levels were lower in FC followed by RC and lowest in NC calves, and similar results were observed in exp.2. It was concluded that the provision of full mother contact along with free choice colostrum suckling from birth to 5 days followed by fenceline mother contact and twice daily suckling at milking time abated the separation and weaning stress and remarkably improved the growth, immune status and health of Murrah buffalo calves as compared to the calves which were allowed only limited contact twice daily or the calves which were weaned at birth.
Modeling and forecasting of milk production in different breeds in Turkey
Authors: YONAR HARUN , YONAR AYNUR , MISHRA PRADEEP , ABOTALEB MOSTAFA , KHATIB ABDULLAH MOHAMMAD GHAZI AL , MAKAROVSKIKH TATIANA , CAM MUSTAFA
Published: September 2022

Identification of milk production is one of the key activities for the Turkish economy in terms of providing economic income for dairy smallholders and meeting consumer demands. This study aims to predict milk production in Turkey using various time series models which are BATS, TBATS, Holt's Linear Trend, ARIMA models, and NNAR. Yearly data from 1991 to 2019 on Milk Production is used in this study. The best time series model is selected from the testing data set (2015 to 2019) based on the lowest Mean Absolute Percentage Error (MAPE). The results of this study showed that the best predicts are obtained for Culture purebred milk production by an ARIMA (1,2,1) model, for Crossbreed milk production by a TBATS Model, for Indigenous milk production by ARIMA (0,2,0) model for total milking cows' production by Holtâ€™s Linear Trend model. Furthermore, these models forecasted an increasing trend in the production of milk from 2020 to 2025. The percentage increases for culture purebred milk, Crossbreed milk production, and Indigenous milk production from 2020 to 2025 are projected to be 40, 20.9 and 10.9%, respectively. Overall, the total milking cows' production is projected to increase by 25% in 2025.
Socio-economic status of Pantja goat rearers of Uttarakhand
Authors: KHADDA B S , SINGH BRIJESH , SINGH S K , SHARMA R K , SHARMA S K , SINGH DEVESH
Published: September 2022

A benchmark survey was conducted to collect the baseline information from the Pantja goat rearers regarding various breeding management practices with special reference to Pantja goats under field condition of Udham Singh Nagar and Nainital districts of Tarai region of the Uttarakhand during a period of two year (April 2015 to March 2017). Majority (90.39%) of goat rearers belonged to Hindu religion, 55.97% of respondents lived in nuclear family with 53.64% having a family size of more than 5 members. Overall literacy rate was 64.96%. Majority of the farmers rearing Pantja goats were from Scheduled castes (43.88%) and 82.95% belonged to the middle age group. Majority of the goat keepers (47.91%) followed animal husbandry as a primary profession and 73.80% were landless. Among the total livestock maintained by the goat keepersâ€™, maximum (81.69%) were goats, 10.84% cattle and 7.47% were buffaloes. The majority of households (71.97%) earned a total income of more than `50,000 followed by 26.36% households with total income between `20,001â€“50,000, 1.55% with a total income between `10,000â€“20,000 and only 0.16% with less than `10,000 per annum.
English Teacher Professional Identity Tensions across Language Schools and Public Universities
Authors: Jawad Golzar  , Mir Abdullah Miri  , Mostafa Nazari
Published: September 2022

While research on language teachers’ identity construction has grown exponentially, little is known about the comparative analysis of language-school and university teachers’ identity construction. This study investigated the identity construction tensions of Afghan English language teachers in two different contexts: language schools and universities. Data were collected from 16 language-school and university teachers through extensive semi-structured interviews. Data analyses indicated similar and different tensions across the two contexts in influencing the teachers’ professional identity construction. Language-school teachers mentioned tensions such as nepotism, low teacher autonomy, and low communication between teachers and policymakers, and university teachers referred to tensions such as large heterogeneous classes, heavy workload, and segregated education. Additionally, both groups lamented over various socio-educational tensions such as the negative impact of war on English learning conceptions, biased perceptions about Afghan teachers, and lack of parental involvement in educational functioning. The study concludes with implications for addressing EFL teachers’ identity tensions.
Viabilidade Econômica da produção de Pimenta-do-reino em pequena escala no município de Tomé-Açu(PA).
Authors: Cardoso Maria Solange , Garcia Wilnalia , Silva Ismael Matos
Published: September 2022

O objetivo do estudo foi analisar por meio dos indicadores Valor Presente Líquido (VPL), Taxa Interna de Retorno (TIR), Relação Benefício-Custo (R B/C) e Ponto de Equilíbrio (PE) a viabilidade econômica e o impacto das variações no preço de venda da cultura da pimenta do reino (Piper nigrum L.). Concluiu-se que a produção de pimenta-do-reino em pequena escala é viável economicamente, pois todos os indicadores mostraram-se positivos, mesmo quando analisados sobre a maior taxa considerada de 10,0% a.a.
Estudo descritivo sobre o emprego em Capanema.PA
Authors: Santana Sanderson de , Silva Joyce Andressa Colares Sales da , Pimentel Gabriela Sousa , Silva Eleci Terezinha Dias da
Published: September 2022

Esta pesquisa visa descrever, de modo quantitativo,os motivos que levam as pessoas a se enquadrarem no grupo de desempregados; verificar se estão procurando emprego; quais as consequências geradas com a perda do emprego e a disposição a encarar novos desafios e superar as dificuldades. Observa-se a importância de um estudo que esclareça e estabeleça bases para difundir o tema do desemprego, e, diante disso, foi analisado a atual situação do desemprego através de questionário a uma amostra de 80 desempregados na cidade de Capanema/PA. Após o resultado da pesquisa obtido, foram analisados os dados para observação dos fatos com o apoio de estatística simples para elaboração de gráficos, tabelas e valores quantitativos.
Patient Awareness about the indications for and complications of sleeve gastrectomy in the western region of Saudi Arabia
Authors: Alzahrani Khalid M. , Faydh Jamal Amin , Althuwaybi Saad Eidhah , Fayez Dakhil Saud Saeed , Althobaiti Fayez Dakhil Allah , Althagafi Bader Abed
Published: September 2022

Introduction and Research Problem: Obesity can be defined as a BMI of 30 kg/m2 or higher. It has been recognized as the 2nd largest cause of avoidable early mortality in the USA. Bariatric surgery is a weight-loss surgical technique that is mostly suggested for morbidly obese individuals (BMI greater than 40) without comorbidities and BMI 35 with comorbidities. The goal of the study was to assess patient awareness about the indications for and complications of, sleeve gastrectomy, as there is an insignificant number of studies related to our topic, in Saudi Arabia. Materials and Methods: An observational cross-sectional study conducted in the western part of Saudi Arabia. The study’s population included all patients of sleeve gastrectomy from the Western Region of Saudi Arabia. The instrument used was an electronic questionnaire, which included questions about knowledge of sleeve gastrectomy indications and complications. Summary of Results: The questionnaire was sent to 451 patients who underwent sleeve gastrectomy, and about 444 patients gave consent to participate. It was found that the participants who were aware of the indications and complications of sleeve gastrectomy before undergoing the procedure were 313 (70.5%) and 303 (68.2%). female patients had significantly more awareness related to the indications (p<0.001) and complications (p=0.001). Patients who had an educational qualification of Masters and above had more awareness regarding indications of SG before surgery than others (p=0.008). Conclusion and Recommendations: According to the findings of our study, knowledge regarding the indications for and complications associated with sleeve gastrectomy is not satisfactory. There is a need to raise public understanding of the indications for and consequences of, sleeve gastrectomy. Key words: Patient awareness, indications, complications, sleeve gastrectomy, Saudi Arabia
Prevalence of Obstructive Sleep Apnea among Patients with Cardiovascular Diseases
Authors: Goweda Reda Abdelmoaty , Elsayed Mahmoud Elshahat , Rady Asmhan Saadeldin , Alnahdi Faisal Saleh , Alqurashi Anas Mohammad , Alessa Turki Talal , Bin Laswad Bassam Musleh , Bin Laswad Azzam Musleh , Althobity Omar Abdulaziz , Alhothali Ammar Safran , Khafagy Abdullah , Metwally Ahmed , Zeid Wael
Published: September 2022

Background: Obstructive sleep apnea (OSA) is the most common sleep disorder that interrupts respiration during sleep. It is associated with increasing cardiovascular disease risk. Aim: To screen for OSA among cardiovascular disease patients. Methods: This is a cross-sectional study that was carried out in Makkah city and 451 patients were recruited. Data of this study was collected using a questionnaire which includes sociodemographic data and STOP-Bang test that consists of 8 questions, and net results of STOP-Bang test scoring was divided into OSA-low risk, OSA-intermediate risk and OSA-high risk. Results: The majority of studied patients were males 315(69.8%), Saudis 370(82%), married 353(78.3%), diabetic 291(64.5%), and their age between 40 to 59 years. 81.4% of the studied patients have OSA-high risk, 9.3% have OSA-intermediate risk while 9.3% have OSA-low risk. The relationship between OSA risk scores and patients’ characteristics shows a statistical significance (p < 0.05) in all patients’ characteristics except using medications for chronic diseases (p 0.228). Conclusion: OSA is highly prevalent among cardiovascular disease patients. Physicians’ awareness regarding screening, diagnosis, and treatment of OSA is essential to prevent cardiovascular disease risks. Keywords: Obstructive Sleep Apnea, Cardiovascular disease
Awareness of benign paroxysmal positional vertigo among the population of Taif city
Authors: Basurrah Mohammed A. , Fageeh Yahya A. , Alziyadi Sultan H. , Alshehri Abdulsalam M. , Alrabie Waleed Khalid , Alruways Meshari M. , Alosaimi Ahmad S. , Alfadli Faisal M.
Published: September 2022

Background: Benign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vestibular vertigo worldwide. Objectives: to evaluate overall knowledge and perception about the disease among the different demographics of the population in Taif city. Methods: a cross-sectional community-based study was done and data was collected via a self-administered Google form questionnaire in Taif city, Saudi Arabia. Data about demographics, knowledge about symptoms of BPPV and how to improve this knowledge were collected. Results: The study included 290 participants; 43.1% were females, 48.3% of them were (18 – 25) years old and 67.6% were university educated. Most (85.9%) of our participants had a history of chronic diseases, 75.9 % of our participants felt dizzy before, 24.1% had a history of Otitis media, and 1.7 % had a history of benign paroxysmal positional vertigo (BPPV). Participants agreed that vertigo is a serious illness, an infectious disease, a rare disease, caused by head trauma, caused by vitamin deficiency, is idiopathic, and lasts from seconds to minutes with a percent of (19.7%, 17.6%, 37.2%, 13.1%, 16.2%, 14.1%, 8.6%, 5.2%) respectively. From the participants’ point of view, awareness can be improved by health practitioners, social media,spreading awareness in companies, spreading awareness in schools, the television, by parents with percentage of (23.6%,28.0%, 11.6%, 20.2%, 16.4%, 0.1%) respectively. Conclusion: A low level of knowledge about vertigo was found among the studied sample. Education level was associated with knowledge level, thus awareness campaigns should be done to raise awareness about BPPV. Keywords: Awareness, benign, paroxysmal, positional, vertigo, Taif
Over time prevalence of illicit substance use in Saudi Arabia
Authors: Alfaifi Abdulrahman , El-Setouhy Maged
Published: September 2022

Illicit substance use disorder is a chronic brain disease. This disease can lead to many negative health outcomes or even death. Recently, Saudi Arabia’s rank was among the top of the world in amphetamine seizures. Drug smuggling as well as conflicts and wars in the surrounding countries might play a role in that. The current paper aimed to review the over time prevalence of illicit substance use in Saudi Arabia. To achieve that, we searched through different databases. We also looked over the United Nations Office on Drugs and Crime (UNODC) reports. The current review found a few articles talking about illicit substance use prevalence in Saudi Arabia; much of that work was about Khat substance. In the end, we concluded that there is a considerable need for further research in this field. Keywords: Khat, amphetamine, cannabis, drug abuse, illicit substance abuse
Paralelização de Algoritmos Genéticos Aplicados ao Problema de Placement em Clusters de Estações de Trabalho
Authors: Knopman Jonas , Aude Júlio S.
Published: September 2022

Este artigo analisa alternativas eficientes de paralelização de algoritmos genéticos aplicados ao problema de placement em circuitos VLSI ou em placas de circuito impresso, considerando o uso de PVM em uma plataforma formada por uma rede de estações de trabalho. Com o objetivo de obter-se inicialmente um algoritmo seqüencial capaz de produzir resultados próximos do ótimo, foi verificado, através de uma análise experimental extensa e detalhada, ser necessário ajustar corretamente os parâmetros de controle do algoritmo. Com estes parâmetros ajustados, o algoritmo mostrou-se bastante adequado à exploração de paralelismo. O artigo apresenta, então, uma proposta de implementação paralela do algoritmo que alcança uma redução significativa da necessidade de comunicação entre os processadores. Esta implementação produziu resultados de mesma qualidade que a versão seqüencial, porém com um speed-up aproximadamente igual a 6 em uma rede composta de 8 estações de trabalho.
Um Sistema de Programação Paralela com Variáveis Compartilhadas para Arquiteturas Distribuídas
Authors: Arantes Luciana Bezerra , Sato Líria Matsumoto
Published: September 2022

Sistemas com Memória Compartilhada Distribuída (DSM) implementam a abstração da memória compartilhada para arquiteturas distribuídas, mas nem sempre oferecem uma linguagem de programação que facilite o desenvolvimento das aplicações. O sistema de programação e processamento CPAR-DSM, aqui apresentado, não só provê o modelo de programação com variáveis compartilhadas, mas também construções de linguagem para expressar o paralelismo, balancear o processamento de laços paralelos e organizar a memória compartilhada de forma hierárquica. Para executar as aplicações numa arquitetura distribuída e simular a existência da memória compartilhada, o suporte de processamento do sistema CPAR-DSM utiliza os mecanismos oferecidos por um sistema DSM, explorando ao máximo o principio da localidade dos dados para obter um melhor desempenho das aplicações.
Pré-processamento de Traces para Auxiliar a Visualização de Programas Paralelos
Authors: Stringhini Denise , Navaux Philippe O. A.
Published: September 2022

O trabalho descreve uma ferramenta de visualização lógica de programas paralelos baseada na análise de traces de execução. A idéia básica consiste em aproveitar as informações fornecidas pela monitoração e que em geral são utilizadas apenas para dirigir animação post-mortem dos programas, e utilizá-las também na montagem das janelas de visualização. Este artigo descreve tanto o pré-processador, quanto as janelas de visualização idealizadas a partir das informações que podem ser obtidas através do pré-processador.