bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S4 from Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer
Authors: Yokoyama Yuichiro , Watanabe Toshiaki , Tamura Yusuke , Hashizume Yoshinobu , Miyazono Kohei , Ehata Shogo
Published: April 2023

Overexpression of DUSP5 accelerates apoptosis of CRC cells (related to Figure 6).
Supplementary Tables S1-S2 from [18F]fluorothymidine PET Informs the Synergistic Efficacy of Capecitabine and Trifluridine/Tipiracil in Colon Cancer
Authors: Kim Seog-Young , Jung Jin Hwa , Lee Haeng Jung , Soh Hyunsu , Lee Sang Ju , Oh Seung Jun , Chae Sun Young , Lee Jai Hyuen , Lee Seung Jin , Hong Yong Sang , Kim Tae Won , Moon Dae Hyuk
Published: April 2023

Table S1 shows RT-PCR primer sequence list. Table S2 is the summary of the in vitro and in vivo data
Supplementary Tables S1-S5, Figure S1 from Androgens Are Differentially Associated with Ovarian Cancer Subtypes in the Ovarian Cancer Cohort Consortium
Authors: Ose Jennifer , Poole Elizabeth M. , Schock Helena , Lehtinen Matti , Arslan Alan A. , Zeleniuch-Jacquotte Anne , Visvanathan Kala , Helzlsouer Kathy , Buring Julie E. , Lee I-Min , Tjønneland Anne , Dossus Laure , Trichopoulou Antonia , Masala Giovanna , Onland-Moret N. Charlotte , Weiderpass Elisabete , Duell Eric J. , Idahl Annika , Travis Ruth C. , Rinaldi Sabina , Merritt Melissa A. , Trabert Britton , Wentzensen Nicolas , Tworoger Shelley S. , Kaaks Rudolf , Fortner Renée T.
Published: April 2023

Supplementary Table S1 provides details on each of the participating studies, including recruitment period, fasting status at blood collection and storage temperature of blood specimens, number of matched controls per case, and the matching criteria employed in each study. Supplementary Table S2 shows the blood sample fraction available, the assays used for androgen measurement, and laboratory coefficients of variation. Supplementary Table S3 includes the geometric means of hormone concentrations by cohort after log2 transformation and standardization. Supplementary Table S4 provides the case characteristics for each of the participating cohorts. Supplementary Table S4 shows the odds ratios (ORs) and 95% confidence intervals (95% CIs) for quintiles of androgen concentrations and overall invasive EOC and serous invasive EOC. Supplementary Figure S1 is a forest plot showing the odds ratios (ORs) and 95% confidence intervals (95% CIs) for a doubling of androgen concentration and Type I EOC in a sensitivity analysis restricted to EOC cases with grade data.
Supp tables 1-5 from Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation
Authors: Bhagat Tushar D. , Chen Si , Bartenstein Matthias , Barlowe A. Trevor , Von Ahrens Dagny , Choudhary Gaurav S. , Tivnan Patrick , Amin Elianna , Marcondes A. Mario , Sanders Mathijs A. , Hoogenboezem Remco M. , Kambhampati Suman , Ramachandra Nandini , Mantzaris Iaonnis , Sukrithan Vineeth , Laurence Remi , Lopez Robert , Bhagat Prafulla , Giricz Orsi , Sohal Davendra , Wickrema Amittha , Yeung Cecilia , Gritsman Kira , Aplan Peter , Hochedlinger Konrad , Yu Yiting , Pradhan Kith , Zhang Jinghang , Greally John M. , Mukherjee Siddhartha , Pellagatti Andrea , Boultwood Jacqueline , Will Britta , Steidl Ulrich , Raaijmakers Marc H.G.P. , Deeg H. Joachim , Kharas Michael G. , Verma Amit
Published: April 2023

Supp Table 1: MDS Patient Disease Characteristics Supp Table 2: Pathways affected by hypermethylation in MDS stroma Supp Table 3: Genes that are methylated and underexpressed in MDS stroma Supp Table 4. MDS patient characteristics for primary MSC sample isolation Supp table 5: WNT Targets
Supplementary information from Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits
Authors: Barbazán Jorge , Alonso-Alconada Lorena , Elkhatib Nadia , Geraldo Sara , Gurchenkov Vasily , Glentis Alexandros , van Niel Guillaume , Palmulli Roberta , Fernández Beatriz , Viaño Patricia , Garcia-Caballero Tomas , López-López Rafael , Abal Miguel , Vignjevic Danijela Matic
Published: April 2023

Word file containing supplementary methods and references
Movie S4 from Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits
Authors: Barbazán Jorge , Alonso-Alconada Lorena , Elkhatib Nadia , Geraldo Sara , Gurchenkov Vasily , Glentis Alexandros , van Niel Guillaume , Palmulli Roberta , Fernández Beatriz , Viaño Patricia , Garcia-Caballero Tomas , López-López Rafael , Abal Miguel , Vignjevic Danijela Matic
Published: April 2023

Movie S4 from Liver Metastasis Is Facilitated by the Adherence of Circulating Tumor Cells to Vascular Fibronectin Deposits
Supplementary Table S2 from Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor
Authors: Gustafsson Robert , Jemth Ann-Sofie , Gustafsson Nina M.S. , Färnegårdh Katarina , Loseva Olga , Wiita Elisée , Bonagas Nadilly , Dahllund Leif , Llona-Minguez Sabin , Häggblad Maria , Henriksson Martin , Andersson Yasmin , Homan Evert , Helleday Thomas , Stenmark Pål
Published: April 2023

Parameters for calculation of Z'.
Supplementary Materials and Methods from SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells
Authors: Kurtsdotter Idha , Topcic Danijal , Karlén Alexandra , Singla Bhumica , Hagey Daniel W. , Bergsland Maria , Siesjö Peter , Nistér Monica , Carlson Joseph W. , Lefebvre Veronique , Persson Oscar , Holmberg Johan , Muhr Jonas
Published: April 2023

This file contains additional description of western blot analysis, immunohistochemistry, antibodies, Sox21 targeting in mouse, bioinformatics, in utero electroporation, proliferation, senescence and cell death assays, NPC cultures and assays, and qRT-PCR.
Supplementary figures from β-Catenin Is a Candidate Therapeutic Target for Myeloid Neoplasms with del(5q)
Authors: Li Liping , Sheng Yue , Li Wenshu , Hu Chao , Mittal Nupur , Tohyama Kaoru , Seba Amber , Zhao You-Yang , Ozer Howard , Zhu Tongyu , Qian Zhijian
Published: April 2023

Supplemental Figure 1. Indo suppresses beta-catenin expression. (A) Luciferase reporter assay of beta-catenin transcription activity. (B) beta-catenin expression in MDSL and UoC-M1 cells after Indo treatment for 72 hours. *, P <0.05. Supplemental Figure 2. Indo induces apoptosis of human MDSL, UoCM1 and KG1 cell lines with a del(5q). The histograms of the flow cytometric analysis of apoptosis of leukemia cell lines treated with 100μM Indo. Supplemental Figure 3. beta-catenin suppression induces apoptosis of human MDSL, UoCM1 and KG1 cell lines with a del(5q). The histograms of the flow cytometric analysis of apoptosis of leukemia cell lines expressing PLKO or PLKO-beta-catenin shRNAs.
Supplementary Data from Noninvasive Interrogation of DLL3 Expression in Metastatic Small Cell Lung Cancer
Authors: Sharma Sai Kiran , Pourat Jacob , Abdel-Atti Dalya , Carlin Sean D. , Piersigilli Alessandra , Bankovich Alexander J. , Gardner Eric E. , Hamdy Omar , Isse Kumiko , Bheddah Sheila , Sandoval Joseph , Cunanan Kristen M. , Johansen Eric B. , Allaj Viola , Sisodiya Vikram , Liu David , Zeglis Brian M. , Rudin Charles M. , Dylla Scott J. , Poirier John T. , Lewis Jason S.
Published: April 2023

Supplemental data detailing the methods and results for the synthesis and in vitro characterization of the radioimmunoconjugates, longitudinal PET imaging and ex vivo analyses in various models described within the main text.
Supplemental Figure 5 from Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis
Authors: Tang Yun-Chi , Yuwen Hui , Wang Kaiying , Bruno Peter M. , Bullock Kevin , Deik Amy , Santaguida Stefano , Trakala Marianna , Pfau Sarah J. , Zhong Na , Huang Tao , Wang Lan , Clish Clary B. , Hemann Michael T. , Amon Angelika
Published: April 2023

DL-PDMP inhibits the proliferation of myeloid leukemia cell lines.
Supplementary Figure Legends from Pharmacokinetics and Pharmacodynamics-Based Mathematical Modeling Identifies an Optimal Protocol for Metronomic Chemotherapy
Authors: Ciccolini Joseph , Barbolosi Dominique , Meille Christophe , Lombard Aurélie , Serdjebi Cindy , Giacometti Sarah , Padovani Laetitia , Pasquier Eddy , André Nicolas
Published: April 2023

Legends of Figures S1-4
Supplementary information from E3 Ligase cIAP2 Mediates Downregulation of MRE11 and Radiosensitization in Response to HDAC Inhibition in Bladder Cancer
Authors: Nicholson Judith , Jevons Sarah J. , Groselj Blaz , Ellermann Sophie , Konietzny Rebecca , Kerr Martin , Kessler Benedikt M. , Kiltie Anne E.
Published: April 2023

Supplemental figures 1-5: S1 - Identification of MRE11 truncation by mass spectrometry and western blot quantification from Fig 1A. S2 - Western blots of protein levels after chloroquine treatment and densitometry of MRE11 levels after PAN and cycloheximide from Fig. 2C,D S3 - Additional cell death analysis by FACS and western blotting supportive of Figs 2 and 3A, S4 - quantification of western blots in Figure 5B, S5 - Additional western blots supportive of data in Figure 6, and data for generation and characterisation of stable cell lines, with further presentation clonogenic assays for cell lines used in Fig 6.
Supplementary Tables from Vitamin D3 Prevents Calcium-Induced Progression of Early-Stage Prostate Tumors by Counteracting TRPC6 and Calcium Sensing Receptor Upregulation
Authors: Bernichtein Sophie , Pigat Natascha , Barry Delongchamps Nicolas , Boutillon Florence , Verkarre Virginie , Camparo Philippe , Reyes-Gomez Edouard , Méjean Arnaud , Oudard Stéphane M. , Lepicard Eve M. , Viltard Mélanie , Souberbielle Jean-Claude , Friedlander Gérard , Capiod Thierry , Goffin Vincent
Published: April 2023

This file contains the list of antibodies (Table S1), and the sequences of primers (Table S2) and siRNAs (Table S3)
Supplementary Materials & Methods from A Metastatic Mouse Model Identifies Genes That Regulate Neuroblastoma Metastasis
Authors: Seong Bo Kyung A. , Fathers Kelly E. , Hallett Robin , Yung Christina K. , Stein Lincoln D. , Mouaaz Samar , Kee Lynn , Hawkins Cynthia E. , Irwin Meredith S. , Kaplan David R.
Published: April 2023

Further details of materials & methods provided in supplementary data.
Figure S6 from LPA Induces Metabolic Reprogramming in Ovarian Cancer via a Pseudohypoxic Response
Authors: Ha Ji Hee , Radhakrishnan Rangasudhagar , Jayaraman Muralidharan , Yan Mingda , Ward Jeremy D. , Fung Kar-Ming , Moxley Katherine , Sood Anil K. , Isidoro Ciro , Mukherjee Priyabrata , Song Yong Sang , Dhanasekaran Danny N.
Published: April 2023

LPA-stimulated HIF1α is an early response
Supplemental materials from Software for the Integration of Multiomics Experiments in Bioconductor
Authors: Ramos Marcel , Schiffer Lucas , Re Angela , Azhar Rimsha , Basunia Azfar , Rodriguez Carmen , Chan Tiffany , Chapman Phil , Davis Sean R. , Gomez-Cabrero David , Culhane Aedin C. , Haibe-Kains Benjamin , Hansen Kasper D. , Kodali Hanish , Louis Marie S. , Mer Arvind S. , Riester Markus , Morgan Martin , Carey Vince , Waldron Levi
Published: April 2023

Supplementary Methods and Example Analyses. This file provides additional detail on the MultiAssayExperiment data class, methods of preparation of the TCGA objects, methods and additional results for the example analyses. It includes Supplemental Figures 1-2 (Mogsa enrichment scores for Hallmark gene sets), Supplemental Figure 3 (correlation between copy number, mRNA, and protein profiles for the NCI-60 cell lines), Supplemental Table 1 (comparison between the features of MultiAssayExperiment and MultiDataSet), Supplemental Table 2 (summary table of TCGA datasets), and Supplemental Table 3 (elements of the MultiAssayExperiment data class).
Supplemental Figures from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Figure S1. Immunohistochemistry analysis of mILC1-iFOXO3.A3 tumors & primary tumor size upon detection of metastasis. Figure S2. Foxo1, Foxo3 and Foxo4 expression levels and depletion in mILC1. Figure S3. Immunohistochemistry analysis of mILC1-shFOXOs tumors & primary tumor size upon detection of metastasis. S4-5 3D Spheroid formation of human breast cancer cells / Expression of catalase and Sod2 in mILC1. Figure S6. FOXOs control PI3K signaling feedback in human cancer cells. Figure S7. Restoring GFR-signaling in mILC1-shFOXOs cells is insufficient to rescue cell proliferation and stress kinase induction. Figure S8. FOXOs mediated gene expression influences a plethora of cellular processes.
Supplementary Figure 5 from PDLIM2 Is a Marker of Adhesion and β-Catenin Activity in Triple-Negative Breast Cancer
Authors: Cox Orla T. , Edmunds Shelley J. , Simon-Keller Katja , Li Bo , Moran Bruce , Buckley Niamh E. , Bustamante-Garrido Milan , Healy Nollaig , O'Flanagan Ciara H. , Gallagher William M. , Kennedy Richard D. , Bernards René , Caldas Carlos , Chin Suet-Feung , Marx Alexander , O'Connor Rosemary
Published: April 2023

Related to Figures 5 and 6: Contains images of PDLIM2 immunocytochemistry staining of PDLIM2-negative TNBC cell lines not included in Figure 5 and additional analysis of TN Breast cells under adhesion versus suspension conditions. Protein expression and quantification of β-catenin phosphorylated on Ser675 are also shown. Immunofluorescence images of HA-PDLIM2 overexpressed in BT549 cells are included.
Figure S2 from FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Authors: Hornsveld Marten , Smits Lydia M.M. , Meerlo Maaike , van Amersfoort Miranda , Groot Koerkamp Marian J.A. , van Leenen Dik , Kloet David E.A. , Holstege Frank C.P. , Derksen Patrick W.B. , Burgering Boudewijn M.T. , Dansen Tobias B.
Published: April 2023

Foxo1, Foxo3 and Foxo4 expression levels and depletion in mILC1.
Figures S1, S2, S3, S4, S5, and S6 from Novel SEC61G–EGFR Fusion Gene in Pediatric Ependymomas Discovered by Clonal Expansion of Stem Cells in Absence of Exogenous Mitogens
Authors: Servidei Tiziana , Meco Daniela , Muto Valentina , Bruselles Alessandro , Ciolfi Andrea , Trivieri Nadia , Lucchini Matteo , Morosetti Roberta , Mirabella Massimiliano , Martini Maurizio , Caldarelli Massimo , Lasorella Anna , Tartaglia Marco , Riccardi Riccardo
Published: April 2023

Characterization of ependymoma lines (S1); Nested two-round PCR for detection of SEC61G-EGFR gene fusion (S2); Expression of mutant EGFR in patient- and xenograft-derived lines (S3); EGFR signaling in MD and MI ependymoma lines and effects of EGFR TKIs (S4); antiproliferative effects of EGFR TKIs in EPV-FL and EPV-FL-MI lines (S5); EGFR labeling of intracranial EPP and EPP-MI tumor sections of AEE788-administered mice (S6).
Figure S2 from The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation
Authors: Weissmann Simon , Cloos Paul A. , Sidoli Simone , Jensen Ole N. , Pollard Steven , Helin Kristian
Published: April 2023

Supplementary Figure S2 shows data from starved mouse neural stem cells, overlaps of CIC bound genes in all studied cell lines as well as size exclusion chromatography and immunostaining for proteins co-purified with CIC.
Figure S6 from miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway
Authors: Salem Mohamed , O'Brien Jacob A. , Bernaudo Stefanie , Shawer Heba , Ye Gang , Brkić Jelena , Amleh Asma , Vanderhyden Barbara C. , Refky Basel , Yang Burton B. , Krylov Sergey N. , Peng Chun
Published: April 2023

Relationship between FOXA2 or VCAN mRNA levels and patient survival.
Supplemental Files from Alternatively-Activated Macrophages Upregulate Mesothelial Expression of P-Selectin to Enhance Adhesion of Ovarian Cancer Cells
Authors: Carroll Molly J. , Fogg Kaitlin C. , Patel Harin A. , Krause Harris B. , Mancha Anne-Sophie , Patankar Manish S. , Weisman Paul S. , Barroilhet Lisa , Kreeger Pamela K.
Published: April 2023

Supplemental File contains 8 Figures: SF1 shows a schematic of the co-culture device, SF2 shows additional details of PLSR model and validation of MIP-1β, SF3 shows validation of MIP-1β impact on SELP/P-selectin in mesothelial cell lines, SF4 shows CD24 expression in HGSOC lines, SF5 shows additional CD24 data for HGSOC lines and validation of CD24 siRNA knockdown, SF6 shows additional IHC of in vivo tissues for P-selectin, SF7 shows the impact of ascites on additional HGSOC lines, and SF8 shows additional immunofluorescent images of P-selectin in HGSOC patients. There are also 4 Tables: ST1 lists genes differentially expressed in LP-9 with AAM co-culture, ST2 lists soluble factors in Bioplex arrays that were not detected, ST3 provides CCR1 and CCR5 qRT-PCR results, and ST4 details the prognostic impact of CD24 in HGSOC patients.
Movie S1 from An Oncolytic Virus Expressing a T-cell Engager Simultaneously Targets Cancer and Immunosuppressive Stromal Cells
Authors: Freedman Joshua D. , Duffy Margaret R. , Lei-Rossmann Janet , Muntzer Alice , Scott Eleanor M. , Hagel Joachim , Campo Leticia , Bryant Richard J. , Verrill Clare , Lambert Adam , Miller Paul , Champion Brian R. , Seymour Leonard W. , Fisher Kerry D.
Published: April 2023

Time-lapse sequence of uninfected control cultures of DLD, NHDF, and T cells.
Supplementary Figure S2 from Extracellular Citrate Affects Critical Elements of Cancer Cell Metabolism and Supports Cancer Development In Vivo
Authors: Mycielska Maria E. , Dettmer Katja , Rümmele Petra , Schmidt Katharina , Prehn Cornelia , Milenkovic Vladimir M. , Jagla Wolfgang , Madej Gregor M. , Lantow Margareta , Schladt Moritz , Cecil Alexander , Koehl Gudrun E. , Eggenhofer Elke , Wachsmuth Christian J. , Ganapathy Vadivel , Schlitt Hans J. , Kunzelmann Karl , Ziegler Christine , Wetzel Christian H. , Gaumann Andreas , Lang Sven A. , Adamski Jerzy , Oefner Peter J. , Geissler Edward K.
Published: April 2023

Krebs cycle activity in the presence of extracellular citrate and absolute citrate levels.
Supplementary Data from DDX3 Activates CBC-eIF3–Mediated Translation of uORF-Containing Oncogenic mRNAs to Promote Metastasis in HNSCC
Authors: Chen Hung-Hsi , Yu Hsin-I , Yang Muh-Hwa , Tarn Woan-Yuh
Published: April 2023

Figure S1. DDX3 expression is correlated with cell invasive activity and ATF4 expression. Figure S2. Microarray-identified genes are enriched for pro-metastatic genes and ATF4 targets, and DDX3 is required for migration and ATF4 expression in all of the HNSCC cell lines examined. Figure S3. DDX3 and ATF4 are required for EMT gene expression. Figure S4. DDX3 does not regulate ATF4 protein stability. Figure S5. DDX3 regulate ATF4 translation independent of ER Stress. Figure S6. The DDX3/CBC/eIF3 complex directly activates the translation of uORF-containing mRNAs in vitro and in vivo. Figure S7. RT-qPCR analysis of luciferase mRNAs in the in vivo translation assay. Figure S8. The CBC and eIF3 complexes are involved in the translation of uORF-containing mRNAs. Table S1. List of sense shRNA or siRNA sequences Table S2. Univariate and multivariate cox regression analyses in HNSCC patient samples. Table S3. List of genes that showed more than two-fold changes upon DDX3 knockdown. Table S4. GO terms enriched in DDX3 knockdown-upregulated or -downregulated genes analyzed by DAVID software. Table S5. List of upstream transcription factors potentially involved in DDX3-regulated genes predicted by IPA software. Table S6. Percentages of siDDX3-downregulated, DDX3-upregulated or non-target genes overlapping with uTIS or non-uTIS genes from TIS-db or with uORF-containing genes from uORFdb. Table S7. Percentages of CBP20 CLIPs or eIF3 CLIPs overlapping with DDX3 CLIPs or eIF4A3 CLIPs. Table S8. Percentages of DDX3 CLIPs, CBP20 CLIPs, eIF3 CLIPs or eIF4A3 CLIPs overlapping with uTIS or non-uTIS genes from TIS-db.
Supplementary Figure S5 from TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis
Authors: Deng Chengcheng , Lin Yu-Xin , Qi Xue-Kang , He Gui-Ping , Zhang Yuchen , Zhang Hao-Jiong , Xu Miao , Feng Qi-Sheng , Bei Jin-Xin , Zeng Yi-Xin , Feng Lin
Published: April 2023

Supplementary Figure S5 from TNFRSF19 Inhibits TGFβ Signaling through Interaction with TGFβ Receptor Type I to Promote Tumorigenesis
Supplementary files from MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis
Authors: Trissal Maria C. , Wong Terrence N. , Yao Juo-Chin , Ramaswamy Rahul , Kuo Iris , Baty Jack , Sun Yaping , Jih Gloria , Parikh Nishi , Berrien-Elliott Melissa M. , Fehniger Todd A. , Ley Timothy J. , Maillard Ivan , Reddy Pavan R. , Link Daniel C.
Published: April 2023

Supplementary Materials and Methods// Supplementary Figure 1. Supporting Figure 1. MIR142 mutations attenuate miR-142-3p and miR-142-5p functions.// Supplementary Figure 2. Supporting Figure 2. Mir142 loss alters differentiation in mature hematopoietic populations.// Supplementary Figure 3. Supporting Figure 3. Mir142 loss alters differentiation in MPPs and HSCs.// Supplementary Figure 4. Supporting Figure 4. Mir142-/- bone marrow exhibits reduced repopulating activity with a loss of HSC lymphoid potential.// Supplementary Figure 5. Supporting Figure 7. Mir142 loss enhances IDH2R172K disease initiating capacity.
Table S2 from Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547
Authors: Kas Sjors M. , de Ruiter Julian R. , Schipper Koen , Schut Eva , Bombardelli Lorenzo , Wientjens Ellen , Drenth Anne Paulien , de Korte-Grimmerink Renske , Mahakena Sunny , Phillips Christopher , Smith Paul D. , Klarenbeek Sjoerd , van de Wetering Koen , Berns Anton , Wessels Lodewyk F.A. , Jonkers Jos
Published: April 2023

Mutations (SNVs) identified for RTKs and genes involved in the MAPK-ERK signaling pathway in the donor, vehicle- and AZD4547-treated tumors.
Supplementary Figures S1-5 from Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547
Authors: Kas Sjors M. , de Ruiter Julian R. , Schipper Koen , Schut Eva , Bombardelli Lorenzo , Wientjens Ellen , Drenth Anne Paulien , de Korte-Grimmerink Renske , Mahakena Sunny , Phillips Christopher , Smith Paul D. , Klarenbeek Sjoerd , van de Wetering Koen , Berns Anton , Wessels Lodewyk F.A. , Jonkers Jos
Published: April 2023

Supplementary Figures S1-5 show additional information regarding the Fgfr2-Tbc1d1 fusion, the effect of AZD4547 on established WESB and WESB-Fgfr2 tumors and tumor-derived cells, the causes of death observed with the different AZD4547 treatment schedules, differential gene expression analysis of multiple RTK family members and the overview of insertions in genes across all tumors used in this study.
Figure S1 from TRIM59 Promotes Gliomagenesis by Inhibiting TC45 Dephosphorylation of STAT3
Authors: Sang Youzhou , Li Yanxin , Song Lina , Alvarez Angel A. , Zhang Weiwei , Lv Deguan , Tang Jianming , Liu Feng , Chang Zhijie , Hatakeyama Shigetsugu , Hu Bo , Cheng Shi-Yuan , Feng Haizhong
Published: April 2023

Effects of FOXG1 knockdown on TRIM59 expression
Appendix from Metabolic Imaging of the Human Brain with Hyperpolarized 13C Pyruvate Demonstrates 13C Lactate Production in Brain Tumor Patients
Authors: Miloushev Vesselin Z. , Granlund Kristin L. , Boltyanskiy Rostislav , Lyashchenko Serge K. , DeAngelis Lisa M. , Mellinghoff Ingo K. , Brennan Cameron W. , Tabar Vivian , Yang T. Jonathan , Holodny Andrei I. , Sosa Ramon E. , Guo YanWei W. , Chen Albert P. , Tropp James , Robb Fraser , Keshari Kayvan R.
Published: April 2023

Details of patient data, QC data, and kinetic model
Supplementary Table S1 from Replication Protein A Availability during DNA Replication Stress Is a Major Determinant of Cisplatin Resistance in Ovarian Cancer Cells
Authors: Bélanger François , Fortier Emile , Dubé Maxime , Lemay Jean-François , Buisson Rémi , Masson Jean-Yves , Elsherbiny Abdelhamid , Costantino Santiago , Carmona Euridice , Mes-Masson Anne-Marie , Wurtele Hugo , Drobetsky Elliot
Published: April 2023

Supplementary Table S1 documents clinical and genetic characteristics of ovarian cancer cell lines.
Supplementary Figure S2 from Replication Protein A Availability during DNA Replication Stress Is a Major Determinant of Cisplatin Resistance in Ovarian Cancer Cells
Authors: Bélanger François , Fortier Emile , Dubé Maxime , Lemay Jean-François , Buisson Rémi , Masson Jean-Yves , Elsherbiny Abdelhamid , Costantino Santiago , Carmona Euridice , Mes-Masson Anne-Marie , Wurtele Hugo , Drobetsky Elliot
Published: April 2023

Supplementary Figure S2 depicts quantification of S phase duration using EdU labelling in ovarian cancer cell lines.
Supplementary Figure S4A-C from Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG24-DFO[89Zr] for Tumor-Specific PET/CT Imaging
Authors: Stangl Stefan , Tei Lorenzo , De Rose Francesco , Reder Sybille , Martinelli Jonathan , Sievert Wolfgang , Shevtsov Maxim , Öllinger Rupert , Rad Roland , Schwaiger Markus , D'Alessandria Calogero , Multhoff Gabriele
Published: April 2023

Histological section of benign fibroblat hyperplasia (A), H&E (B), and Hsp70 (C) immunohistochemical staining
Supplementary Figure 5A-E from Preclinical Evaluation of the Hsp70 Peptide Tracer TPP-PEG24-DFO[89Zr] for Tumor-Specific PET/CT Imaging
Authors: Stangl Stefan , Tei Lorenzo , De Rose Francesco , Reder Sybille , Martinelli Jonathan , Sievert Wolfgang , Shevtsov Maxim , Öllinger Rupert , Rad Roland , Schwaiger Markus , D'Alessandria Calogero , Multhoff Gabriele
Published: April 2023

In vitro characterization of TPP-PEG24-DFO[89Zr]. KD analysis (A), IC50 (B), internalization kinetics (C), short-term (D) and long-term (E) time-activity analysis
Table S3-S6 from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Authors: Hiller Björn , Hoppe Anja , Haase Christa , Hiller Christina , Schubert Nadja , Müller Werner , Reijns Martin A.M. , Jackson Andrew P. , Kunkel Thomas A. , Wenzel Jörg , Behrendt Rayk , Roers Axel
Published: April 2023

This file contains histology of skin and skin lesions of RNaseH2EKO mice with intact or defective Trp53 alleles.
Tables S1 to S4 from miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis–Associated Genes
Authors: Croset Martine , Pantano Francesco , Kan Casina W.S. , Bonnelye Edith , Descotes Françoise , Alix-Panabières Catherine , Lecellier Charles-Henri , Bachelier Richard , Allioli Nathalie , Hong Saw-See , Bartkowiak Kai , Pantel Klaus , Clézardin Philippe
Published: April 2023

Table S1 shows clinical and pathological characteristics of breast cancer patients. Table S2 shows association of miR-30s expression levels in primary breast tumors with clinicopathological characteristics of breast cancer patients. Table S3 shows prognostic value of miR-30s in breast cancer for RFS. Table S4 shows in silico targets of miR-30 family members.
Supplementary Figure Legends from miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis–Associated Genes
Authors: Croset Martine , Pantano Francesco , Kan Casina W.S. , Bonnelye Edith , Descotes Françoise , Alix-Panabières Catherine , Lecellier Charles-Henri , Bachelier Richard , Allioli Nathalie , Hong Saw-See , Bartkowiak Kai , Pantel Klaus , Clézardin Philippe
Published: April 2023

Legends to Supplementary Figures S1 to S11.
Supplementary Figures (S1-S7) from Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer
Authors: Ubellacker Jessalyn M. , Baryawno Ninib , Severe Nicolas , DeCristo Molly J. , Sceneay Jaclyn , Hutchinson John N. , Haider Marie-Therese , Rhee Catherine S. , Qin Yuanbo , Gregory Walter M. , Garrido-Castro Ana C. , Holen Ingunn , Brown Janet E. , Coleman Robert E. , Scadden David T. , McAllister Sandra S.
Published: April 2023

Supplemental Figure 1 shows the tumor masses of the subcutaneous tumors shown in Figure 1, as well as the flow cytometry gating strategy of M/OCP populations and the osteoclast differentiation assay experimental schematic. Supplemental Figure 2 shows representative images and the flow cytometry gating strategy for the in vitro osteoclast differentiation assay demonstrated in Figure 2. Supplemental Figure 3 shows that ZA inhibits breast cancer metastasis in a manner that is counteracted by G-CSF in intratibial injections, subcutaneous bone marrow functional assays, and with intracardiac injections of the B1 cell line following pre-treatment with Ctl or ZA and/or recombinant G-CSF. Supplemental Figure 4 shows the tumor masses of the subcutaneous tumors shown in Figure 4, as well as the plasma ALP and NTX concentrations in nude mice with and without ZA treatment. Supplemental Figure 5 shows the representative images and quantifications of the in vitro osteoclast differentiation assay with whole bone marrow from Ctl- or ZA- donors. Supplemental Figure 6 shows the volcano plots, heatmaps of differentially expressed genes, and gene ontology categories for the RNA-sequencing analysis of whole bone marrow from mice treated with Ctl, ZA, G-CSF, or ZA+G-CSF. Supplemental Figure 7 shows the determination of cut point analyses for the plasma G-CSF concentrations and patient outcome data shown in Figure 7.
Figure S1 from Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin
Authors: Hiller Björn , Hoppe Anja , Haase Christa , Hiller Christina , Schubert Nadja , Müller Werner , Reijns Martin A.M. , Jackson Andrew P. , Kunkel Thomas A. , Wenzel Jörg , Behrendt Rayk , Roers Axel
Published: April 2023

Efficient inactivation of RNase H2 in the epidermis, and skin phenotype of Rnaseh2EKO mice.
Supplemental Tables S1-S7 from Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer
Authors: Ubellacker Jessalyn M. , Baryawno Ninib , Severe Nicolas , DeCristo Molly J. , Sceneay Jaclyn , Hutchinson John N. , Haider Marie-Therese , Rhee Catherine S. , Qin Yuanbo , Gregory Walter M. , Garrido-Castro Ana C. , Holen Ingunn , Brown Janet E. , Coleman Robert E. , Scadden David T. , McAllister Sandra S.
Published: April 2023

Functionally enriched gene ontology (GO) terms and differentially enriched genes for the RNA-sequencing tables and heatmaps included in the manuscript text.
Supplementary Data from CSTF2-Induced Shortening of the RAC1 3′UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder
Authors: Chen Xin , Zhang Jia-Xing , Luo Jun-Hang , Wu Song , Yuan Gang-Jun , Ma Ning-Fang , Feng Yong , Cai Mu-Yan , Chen Ri-Xin , Lu Jun , Jiang Li-Juan , Chen Jie-Wei , Jin Xiao-Han , Liu Hai-Liang , Chen Wei , Guan Xin-Yuan , Kang Tie-Bang , Zhou Fang-Jian , Xie Dan
Published: April 2023

Supplementary Figure S1. Identification of 3'UTR shortening of RALA and RAC1 from UCB, colorectal carcinoma, hepatocellular carcinoma and non-small cell lung cancer samples. Supplementary Figure S2. RAC1 with short 3'UTR promotes tumorigenesis and produces more protein due to evasion of miRNA-mediated repression. Supplementary Figure S3. Screening of APA factors that contribute to the PAS selection of RAC1 in UCB. Supplementary Figure S4. CSTF2 regulates colony formation and invasiveness abilities of shorter RAC1 isoform in UCB. Supplementary Table S1. PDUI value calculated from DaPars analysis of 15 pairs of UCB and adjacent normal bladder tissues. Supplementary Table S2. KEGG pathway analyses of APA genes identified from RNA-Seq. Supplementary Table S3. RAC1 genomic mutations identified from TCGA UCB database. Supplementary Table S4. Correlation between the expression of CSTF2 and clinicopathologic characteristics of UCB patients
Supplementary Table S1-S3 from Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer
Authors: Su Wenmei , Feng Shumei , Chen Xiuyuan , Yang Xia , Mao Rui , Guo Chunfang , Wang Zhuwen , Thomas Dafydd G. , Lin Jules , Reddy Rishindra M. , Orringer Mark B. , Chang Andrew C. , Yang Zhixiong , Beer David G. , Chen Guoan
Published: April 2023

Supplementary Tables S1-S3. S1: MIR22HG level and clinical variables from validation set of 101 LUADs measured by qRT-PCR. S2: genomic alterations of lung cancer cell lines used in this study. S3: Primer and siRNA sequences, as well as antibodies used in this study.
Supplementary Method from Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer
Authors: Su Wenmei , Feng Shumei , Chen Xiuyuan , Yang Xia , Mao Rui , Guo Chunfang , Wang Zhuwen , Thomas Dafydd G. , Lin Jules , Reddy Rishindra M. , Orringer Mark B. , Chang Andrew C. , Yang Zhixiong , Beer David G. , Chen Guoan
Published: April 2023

Supplementary Methods about RNAs extraction and quantitative real-time RT-PCR, proteins extraction, immunoblot analysis and tissue array, cell cycle analysis by flow cytometry, and MIR22HG lentiviral expression construct transfection.
Figure S4 from Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
Authors: Moses Michael A. , Kim Yeong Sang , Rivera-Marquez Genesis M. , Oshima Nobu , Watson Matthew J. , Beebe Kristin E. , Wells Catherine , Lee Sunmin , Zuehlke Abbey D. , Shao Hao , Bingman William E. , Kumar Vineet , Malhotra Sanjay V. , Weigel Nancy L. , Gestwicki Jason E. , Trepel Jane B. , Neckers Leonard M.
Published: April 2023

Effect of JG98 on endogenous or exogenous FL-AR/ARv7 protein/target gene expression; cell lysate input for Figure 4A
Figure S1 from Targeting the Hsp40/Hsp70 Chaperone Axis as a Novel Strategy to Treat Castration-Resistant Prostate Cancer
Authors: Moses Michael A. , Kim Yeong Sang , Rivera-Marquez Genesis M. , Oshima Nobu , Watson Matthew J. , Beebe Kristin E. , Wells Catherine , Lee Sunmin , Zuehlke Abbey D. , Shao Hao , Bingman William E. , Kumar Vineet , Malhotra Sanjay V. , Weigel Nancy L. , Gestwicki Jason E. , Trepel Jane B. , Neckers Leonard M.
Published: April 2023

Structure of C86 and its effects on endogenous or exogenous FL-AR/ARv7 protein/target gene expression and VCaP viability
Supplementary movie1 from Optimized Dosing Schedule Based on Circadian Dynamics of Mouse Breast Cancer Stem Cells Improves the Antitumor Effects of Aldehyde Dehydrogenase Inhibitor
Authors: Matsunaga Naoya , Ogino Takashi , Hara Yukinori , Tanaka Takahiro , Koyanagi Satoru , Ohdo Shigehiro
Published: April 2023

The bioluminescence of cultured Aldh3a1::Luc- expressing 4T1 cells was recorded using a real-time monitoring system. The ALDH-positive populations of Aldh3a1::Luc-expressing 4T1 cells were cultured on VECELL 3D inserts. This VECELL 3D insert was co-cultured into 35 mm culture dish which were seeding the cells treated with 100 nM dexamethasone for synchronization of their circadian clocks.
Supplementary Methods from p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Authors: Kajiwara Chihiro , Fumoto Katsumi , Kimura Hirokazu , Nojima Satoshi , Asano Keita , Odagiri Kazuki , Yamasaki Makoto , Hikita Hayato , Takehara Tetsuo , Doki Yuichiro , Morii Eiichi , Kikuchi Akira
Published: April 2023

Additional methods used in this study.
Supplementary Figure 6 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

AICDA CRISPR1 and CRISPR2 mutations.
Supplementary Figure S2 from p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Authors: Kajiwara Chihiro , Fumoto Katsumi , Kimura Hirokazu , Nojima Satoshi , Asano Keita , Odagiri Kazuki , Yamasaki Makoto , Hikita Hayato , Takehara Tetsuo , Doki Yuichiro , Morii Eiichi , Kikuchi Akira
Published: April 2023

DKK3-CKAP4 signaling-dependent activation of Akt.
Supplementary Figure 3 from The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
Authors: El Kadi Najwa , Wang Luo , Davis April , Korkaya Hasan , Cooke Alexander , Vadnala Varun , Brown Noah A. , Betz Bryan L. , Cascalho Marilia , Kalemkerian Gregory P. , Hassan Khaled A.
Published: April 2023

APOBEC and AICDA expression after exposure to gefitinb.
Supplementary Figure S1 from p63-Dependent Dickkopf3 Expression Promotes Esophageal Cancer Cell Proliferation via CKAP4
Authors: Kajiwara Chihiro , Fumoto Katsumi , Kimura Hirokazu , Nojima Satoshi , Asano Keita , Odagiri Kazuki , Yamasaki Makoto , Hikita Hayato , Takehara Tetsuo , Doki Yuichiro , Morii Eiichi , Kikuchi Akira
Published: April 2023

Expression of DKK1 and DKK3 in public database.
Supplementary table S5 from Targeting USP7 Identifies a Metastasis-Competent State within Bone Marrow–Resident Melanoma CTCs
Authors: Vishnoi Monika , Boral Debasish , Liu Haowen , Sprouse Marc L. , Yin Wei , Goswami-Sewell Debalina , Tetzlaff Michael T. , Davies Michael A. , Oliva Isabella C. Glitza , Marchetti Dario
Published: April 2023

Genomic profiling and clinical significance of patient-derived Lin-neg/Melan-A+ CTC-enriched population through AmpliSeq Ion Torrent DNA sequencing platform
Fig, S1 from RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis
Authors: Zeng Fanxin , Chen Xiao , Cui Weiyi , Wen Wei , Lu Fujian , Sun Xueting , Ma Dongwei , Yuan Ye , Li Zezhong , Hou Ning , Zhao Hong , Bi Xinyu , Zhao Jianjun , Zhou Jianguo , Zhang Yan , Xiao Rui-Ping , Cai Jianqiang , Zhang Xiuqin
Published: April 2023

Figure S1. High levels of RIPK1 Expression shows Poor Prognosis. (A) Relative levels of RIPK1 expression in CRC on different tumor stages (n = 40). (B) Relative levels of RIPK1 expression between alive (n=30) and death (n=8) in CRC.
Supplementary Figure 3 from Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell–Cell Biophysical Properties in Prostate Cancer
Authors: Rubenstein Cynthia S. , Gard Jaime M.C. , Wang Mengdie , McGrath Julie E. , Ingabire Nadia , Hinton James P. , Marr Kendra D. , Simpson Skyler J. , Nagle Raymond B. , Miranti Cindy K. , Warfel Noel A. , Garcia Joe G.N. , Arif-Tiwari Hina , Cress Anne E.
Published: April 2023

ECM proteolysis, α6 integrin, and E-cadherin expression in 3D Matrigel invasive networks
Supplementary Data from Zebrafish MITF-Low Melanoma Subtype Models Reveal Transcriptional Subclusters and MITF-Independent Residual Disease
Authors: Travnickova Jana , Wojciechowska Sonia , Khamseh Ava , Gautier Philippe , Brown Daniel V. , Lefevre Thomas , Brombin Alessandro , Ewing Ailith , Capper Amy , Spitzer Michaela , Dilshat Ramile , Semple Colin A. , Mathers Marie E. , Lister James A. , Steingrimsson Eiríkur , Voet Thierry , Ponting Chris P. , Patton E. Elizabeth
Published: April 2023

Supplementary File comprising of Supplementary Material and Methods, Supplementary References and Supplementary Figures S1-S7. Figure S1: IHC of melanoma and proliferation markers; Figure S2: Images of fish used for bulk RNA-seq, Figure S3: Heatmaps of most variable genes and MITF target genes; Figure S4: describes transcriptome comparison of the three melanoma models; Figure S5: apoptosis at the site of melanoma regression; Figure S6: fish used for low cell number and single cell RNA-seq; Figure S7: MITF-independent cells present in residual disease and primary tumour.
Supplementary Data from ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer
Authors: Vartanian Steffan , Lee James , Klijn Christiaan , Gnad Florian , Bagniewska Maria , Schaefer Gabriele , Zhang Donglu , Tan Jenille , Watson Sara A. , Liu Liling , Chen Honglin , Liang Yuxin , Watanabe Colin , Cuellar Trinna , Kan David , Hartmaier Ryan J. , Lau Ted , Costa Michael R. , Martin Scott E. , Merchant Mark , Haley Benjamin , Stokoe David
Published: April 2023

Supplementary methods and figure legends
Supplementary Data from Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer
Authors: Silberman Alon , Goldman Omer , Boukobza Assayag Odeya , Jacob Adi , Rabinovich Shiran , Adler Lital , Lee Joo Sang , Keshet Rom , Sarver Alona , Frug Julia , Stettner Noa , Galai Sivan , Persi Erez , Halpern Keren Bahar , Zaltsman-Amir Yehudit , Pode-Shakked Ben , Eilam Raya , Anikster Yair , Nagamani Sandesh C.S. , Ulitsky Igor , Ruppin Eytan , Erez Ayelet
Published: April 2023

Supplementary Figures 1-5 further support our findings regarding the contribution to the maintenance of intracellular pH for ASS1 downregulated cancer cells
Supplementary Tables from S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma
Authors: Xiao Yiren , Zhao Hongjuan , Tian Lei , Nolley Rosalie , Diep Anh N. , Ernst Anne , Fuh Katherine C. , Miao Yu Rebecca , von Eyben Rie , Leppert John T. , Brooks James D. , Peehl Donna M. , Giaccia Amato J. , Rankin Erinn B.
Published: April 2023

Document contains Supplemental Table 1-4ï¼šSupplementary Table S1 and Supplementary Table S2 shows the gene expression profile in 786-O and M62 cell transfected with shSCM1 and shAXL1. Supplementary Table S3 shows the List of genes with >2 fold change in 786-O and M62 cells with AXL knockdown. Supplementary Table S4 shows the List of genes with >2 fold downregulation in 786-O and M62 cells with AXL knockdown.
Figure S3 from S100A10 Is a Critical Mediator of GAS6/AXL–Induced Angiogenesis in Renal Cell Carcinoma
Authors: Xiao Yiren , Zhao Hongjuan , Tian Lei , Nolley Rosalie , Diep Anh N. , Ernst Anne , Fuh Katherine C. , Miao Yu Rebecca , von Eyben Rie , Leppert John T. , Brooks James D. , Peehl Donna M. , Giaccia Amato J. , Rankin Erinn B.
Published: April 2023

Genetic knockdown of AXL in ccRCC cells reduces plasmin production in vitro.
Figure S7 from The Deubiquitylase OTUB1 Mediates Ferroptosis via Stabilization of SLC7A11
Authors: Liu Tong , Jiang Le , Tavana Omid , Gu Wei
Published: April 2023

The loss of OTUB1 induces ferroptosis in UM-UC-3 cells
Supplementary Data from N6-Methyladenosine Modulates Nonsense-Mediated mRNA Decay in Human Glioblastoma
Authors: Li Fuxi , Yi Yang , Miao Yanyan , Long Wenyong , Long Teng , Chen Siyun , Cheng Weisheng , Zou Changye , Zheng Yueyuan , Wu Xingui , Ding Junjun , Zhu Kaiyu , Chen Delin , Xu Qiongcong , Wang Jinkai , Liu Qing , Zhi Feng , Ren Jian , Cao Qi , Zhao Wei
Published: April 2023

Supplementary Figures and Methods
Supplementary Table 2 from An ERG Enhancer–Based Reporter Identifies Leukemia Cells with Elevated Leukemogenic Potential Driven by ERG-USP9X Feed-Forward Regulation
Authors: Aqaqe Nasma , Yassin Muhammad , Yassin Abed Alkader , Ershaid Nour , Katz-Even Chen , Zipin-Roitman Adi , Kugler Eitan , Lechman Eric R. , Gan Olga I. , Mitchell Amanda , Dick John E. , Izraeli Shai , Milyavsky Michael
Published: April 2023

Supplementary Table 2
Supplementary Figures S5-S6 from DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs
Authors: Oshima Go , Poli Elizabeth C. , Bolt Michael J. , Chlenski Alexandre , Forde Martin , Jutzy Jessica M.S. , Biyani Neha , Posner Mitchell C. , Pitroda Sean P. , Weichselbaum Ralph R. , Khodarev Nikolai N.
Published: April 2023

Supplemental Figures S5-S6. Distribution of CpG sites, transcription start site and methylation-dependent CTCF binding region in DLK1-MEG9 region.
Figure S9 from Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
Authors: Housley Stephen N. , Nardelli Paul , Carrasco Dario I. , Rotterman Travis M. , Pfahl Emily , Matyunina Lilya V. , McDonald John F. , Cope Timothy C.
Published: April 2023

Immunostaining of sensory neurons in dorsal root ganglia
Supplementary Figure 4 from Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity
Authors: Leonetti Daniela , Estéphan Hala , Ripoche Natacha , Dubois Nolwenn , Aguesse Audrey , Gouard Sébastien , Brossard Lisa , Chiavassa Sophie , Corre Isabelle , Pecqueur Claire , Neunlist Michel , Hadchity Elie , Gaugler Marie-Hélène , Mahé Maxime M. , Paris François
Published: April 2023

SupFigure4
Supplementary Figure 2 from Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity
Authors: Leonetti Daniela , Estéphan Hala , Ripoche Natacha , Dubois Nolwenn , Aguesse Audrey , Gouard Sébastien , Brossard Lisa , Chiavassa Sophie , Corre Isabelle , Pecqueur Claire , Neunlist Michel , Hadchity Elie , Gaugler Marie-Hélène , Mahé Maxime M. , Paris François
Published: April 2023

SupFigure2
Supplementary Figure 1 from Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity
Authors: Leonetti Daniela , Estéphan Hala , Ripoche Natacha , Dubois Nolwenn , Aguesse Audrey , Gouard Sébastien , Brossard Lisa , Chiavassa Sophie , Corre Isabelle , Pecqueur Claire , Neunlist Michel , Hadchity Elie , Gaugler Marie-Hélène , Mahé Maxime M. , Paris François
Published: April 2023

SupFigure 1
Figure Legends from Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
Authors: Housley Stephen N. , Nardelli Paul , Carrasco Dario I. , Rotterman Travis M. , Pfahl Emily , Matyunina Lilya V. , McDonald John F. , Cope Timothy C.
Published: April 2023

Supplemental Figure Legends
Table S1-S9 from MYC Drives Group 3 Medulloblastoma through Transformation of Sox2+ Astrocyte Progenitor Cells
Authors: Tao Ran , Murad Najiba , Xu Zhenhua , Zhang Peng , Okonechnikov Konstantin , Kool Marcel , Rivero-Hinojosa Samuel , Lazarski Christopher , Zheng Pan , Liu Yang , Eberhart Charles G. , Rood Brian R. , Packer Roger , Pei Yanxin
Published: April 2023

RNA-Seq analysis
Supplementary Table 1 from IL26, a Noncanonical Mediator of DNA Inflammatory Stimulation, Promotes TNBC Engraftment and Progression in Association with Neutrophils
Authors: Trotter Timothy N. , Shuptrine Casey W. , Tsao Li-Chung , Marek Robert D. , Acharya Chaitanya , Wei Jun-Ping , Yang Xiao-Yi , Lei Gangjun , Wang Tao , Lyerly Herbert Kim , Hartman Zachary C.
Published: April 2023

CRISPR screen results
Table S3 from Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
Authors: Henderson Fiona , Johnston Hannah R. , Badrock Andrew P. , Jones Emrys A. , Forster Duncan , Nagaraju Raghavendar T. , Evangelou Christos , Kamarashev Jivko , Green Michael , Fairclough Michael , Ramirez Irene Barinaga-Rementeria , He Shuning , Snaar-Jagalska B. Ewa , Hollywood Katherine , Dunn Warwick B. , Spaink Herman P. , Smith Michael P. , Lorigan Paul , Claude Emmanuelle , Williams Kaye J. , McMahon Adam W. , Hurlstone Adam
Published: April 2023

From UPLC-MS, metabolites extracted in non-aqueous solvent whose abundance in V12RAS RGP or V12RAS VGP skin differs significantly when compared to wild-type skin.
Table S2 from Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
Authors: Henderson Fiona , Johnston Hannah R. , Badrock Andrew P. , Jones Emrys A. , Forster Duncan , Nagaraju Raghavendar T. , Evangelou Christos , Kamarashev Jivko , Green Michael , Fairclough Michael , Ramirez Irene Barinaga-Rementeria , He Shuning , Snaar-Jagalska B. Ewa , Hollywood Katherine , Dunn Warwick B. , Spaink Herman P. , Smith Michael P. , Lorigan Paul , Claude Emmanuelle , Williams Kaye J. , McMahon Adam W. , Hurlstone Adam
Published: April 2023

From microarray analysis, genes from VGP melanocyte neoplasia whose transcripts are significantly up- or down-regulated compared to wild-type tissue that are associated with lipid metabolism and are not differentially expressed also in BRAFV600E or V12RAS RGP samples.