bluuebunny/crossref_metadata_2025 huggingface dataset:
Pendidikan Anak dalam Perspektif Al-Qur’an Al-Karim
Authors: Hadlori Muhamad Abid , Saket Saeed Abdullah Saeed , Tsauri Sidiq Samsi
Published: April 2022

The Qur'an is the greatest holy book that was ever revealed on the surface of the earth, entrusted to the best and most honest people of its time and sent down in the most blessed city on earth. In it is full of instructions for all mankind in order to achieve salvation both in this world and in the hereafter. The scriptures that have been proven from time to time are superior in glory and proven to be strong in authenticity. So it is appropriate for a Muslim to make it a guide in his life. Among the aspects that can be taken from the Qur'an is how the Qur'an describes and explains the educational methods applied to children, showing clearly how Islam treats children as the main goal in Islamic education in order to produce a generation capable of carrying out the task. -Duties and mandates of Muslims in the future. This research is intended to collect explanations of the verses of the Qur'an related to education for children through a literature study approach. With the scope of the research based on the explanation from Taisir Karim Ar-Rahman fi Tafsir Kalam Al-Mannan's commentary book, especially explanations related to the education of children. This research is aimed at returning the educational vision of Muslims back to the guidance of the Qur'an and Al-Sunnah which are proven to be able to create an advanced and strong Islamic civilization by practicing the guidance of the Qur'an and Al-Sunnah and applying it in their lives so as to create generations of people. strong, monotheistic, and noble.
Investigating the impact of cutting down nearby trees on measured values of the atmospheric electric potential gradient data
Authors: Buzás Attila , Bór József
Published: April 2022

A group of trees located at the eastern side of the atmospheric electric potential gradient (PG) measurement site in the Széchenyi István Geophysical Observatory at Nagycenk (NCK) was cut down on the 24th February in 2020. In order to assess the impact of this event on the PG measurements, an electrostatic numerical model was built to model the effect of the removal of trees. Moreover, the PG data recorded between 2017 and 2021 were analyzed. It was found that the PG increased by up to 52% after the trees in question were cut down. Based on the numerical model calculations this enhancement was expected to be larger, 78%. Further investigations concerning the seasonal variation of the PG recorded in 2017–2021 affirm that this increase is not part of the regular seasonal variation of the PG and it is an anomaly most likely caused by the diminished electrostatic shielding effect due to the fewer remaining trees.
STUDI EKSPLANATORI-KONFIRMATORI KEHIDUPAN KRISTEN BERDASARKAN LUKAS 16:19-31 DI KALANGAN HAMBA TUHAN SE-KABUPATEN JEMBER JAWA TIMUR
Authors: Widjaja Soehadi , Purwoko Paulus Sentot , Suharto Daniel , Sukarna Timotius
Published: April 2022

The number of theologies that breathe success appears among God's servants throughout Jember district, which are alleged to have deviated from the biblical Christian life. This encourages this research to be carried out. The aim is to find out how much the level of application, dimensions and background categories that tend to influence the implementation of Christian life based on Luke 16: 19-31 among the servants of God in Jember Regency, East Java. The method used is the quantitative method in the form of explanatory-confirmatory studies of the text of Luke 16: 19-31 and literature studies related to the topic of Christian life as well as examining moderate variables in the form of categories of the background of the object of research. As a result, first, the level of implementation of Christian life based on Luke 16: 19-31 among God's servants throughout Jember district is in the "medium" category (not yet optimal). This is because God's servants in Jember district have been influenced by a theology characterized by success that has distorted the Christian life. Second, the dimensions of the outer and inner life of God's servants who live simply, are the most significant moral and spiritual forces that influence the application of the Christian life based on Luke 16: 19-31.Third, ethnic backgrounds are more dominant in determining the implementation of biblical Christian life, including occupation and age, this is because the majority of God's servants in Jember Regency are Javanese (46.7%) who have long served there, which by themselves can adapt to Javanese people who live simply so they are able to live a Christian life according to the Gospel of Luke 16: 19-31.
TINJAUAN TEOLOGIS SIKAP GEREJA KRISTEN SUMBA TERHADAP STRATIFIKASI SOSIAL YANG ADA DI JEMAAT PAU-UMABARA
Authors: Nugroho Fibry Jati , Praing Umbu Yanto Namu
Published: April 2022

Social stratification is a culture that is still inherent in the life of the Sumba tribe in East Nusa Tenggara. In the culture of the Sumbanese people, social stratification is very important because it will determine the level of one's position in the community. According to the people of Sumba, when the social stratification occurs, there will be a difference between maramba and ata in community life. Because when someone is in the maramba group, he will be seen as a person who has the highest position and deserves respect. But if you are in an ata group, you will be looked down upon because you have a very low position. Likewise what happened in the Pau-Umbara congregation, they still practice social stratification and they believe that with social stratification, everyone will respect each other, respect each other. Through a qualitative approach using descriptive methods, this research examines the attitude of the Sumba Christian Church towards the existing social stratification in the Pau-Umabara congregation. It is found that the Church provides a new understanding of stratification in the congregation.
IMPLEMENTASI HIDUP ORANG BENAR BERDASARKAN MAZMUR 92:1-16 DI KALANGAN JEMAAT GEREJA PANTEKOSTA ISA ALMASIH SE-JAWA BARAT
Authors: Kurniawan Martha Mulyani , Suparti Hana , Sukarna Timotius
Published: April 2022

The diversity of religious people in Indonesia shows how many people recognize God as worthy of worship. All religions teach doctrines that devotees should adhere to. In reality, though, many people profess to be religious but fail to practice the religious teachings that they carry out so much as a wicked person. Even if they do not worship god wholeheartedly, God blesses them. It often makes the congregation feel that the lives of the wicked are more comfortable, while those who live righteously in doing the word of the Lord are walking into a lot of trouble. The purpose of this study is to know the magnitude of the implementation of a righteous person's life, to know which dimension most predominates the implementation of the righteous person, and to know the background category that most determines the implementation of a righteous person's life based on Psalm 92:1-16 among church congregations by the quantitative method. It's a survey method. Research Result: The application of a righteous person's life based on Psalm 92:1-16 in the congregation is surprisingly moderate. The dominant dimension in the application of a righteous person's life based on Psalm 92:1-16 is life for God. The background category of the ones who most determine the lives of the righteous based on Psalm 92:1-16 is education.
SOCIAL ECONOMY ACTORS IN POLAND'S CLIMATE POLICY
Authors: Jędrasik Ilona , Józefiak Marek
Published: April 2022

Climate policy is considered one of the most difficult among public policies due to its complexity, urgency and strong economic impact. Social economy actors have the potential to play an important role in the functioning of this policy. This article presents the role and describes the activities of social economy actors in programming, implementation, scenario planning and evaluation of climate policy in Poland. The article also indicates the products and services produced by these entities in different areas of this policy.
SOCIAL ECONOMY ENTITIES IN HEALTH POLICY
Authors: Raczek Melanie
Published: April 2022

The purpose of this article is to analyze the sectoral health policy with particular emphasis on the activities of social economy entities. This paper deals with the characteristics of health policy and address the problem of the role of social economy entities in health policy programming and its implementation. The paper presents and refers to numerous examples of activities of social economy entities that have an impact on creating health policy. It should be noted that social economy entities play an important role in the process of inventing and implementing changes in health policy in Poland.
THE EDUCATION POLICY AND THE ACTIVITY OF SOCIAL ECONOMY ENTITIES
Authors: Zybała Andrzej
Published: April 2022

The author presents the issue of the role of the social economy entities in education policy. He points at their growing activity in policy formulation and implementation. Their role allows them to influence – directly and indirectly – both of the policy levels as well as influence the market supply in the area of various market services. They play the supplementary role in both domains, but at the same time – what seems to be critical – increase the pace at which the education system adapts to changing reality to live up to the expectations as to educate and raise the creative younger generation. Evidence of this is the structure of their activity, including the diversity of programmes they carry out, which are designed to implement modern teaching methods, support open-mindedness, proper civic culture, etc.
An Analysis of Heritage Speaker Writing Development Over Three Months of Instruction
Authors: Miller Lauren
Published: April 2022

Despite growing numbers of heritage speakers (HS) in all levels of language classrooms, much remains to be understood about how instruction affects acquisition and/or maintenance of a heritage language. The present study adds to this line of research by exploring writing tasks completed by university-level HS of Spanish over the course of a semester to determine which areas HS struggle most with and how this changes as a result of instruction. Results show that error count did decrease, suggesting improvement. The highest proportion of errors came from difficulties with accent marks and other orthography, which also showed the most improvement at the end of the study. Interestingly, accent marks used for purely orthographic reasons (tú vs. tu), did not show the same level of improvement, suggesting that regular patterns may be easier to learn and apply to subsequent production activities in comparison to areas requiring memorization, such as accents differentiating lexical items, non-canonical gender, and vocabulary.
Effect of Climate Change on Wheat Productivity
Authors: Elahi Ihsan , Saeed Uzair , Wadood Abdul , Abbas Amjad , Nawaz Hira , Jabbar Sohail
Published: April 2022

Climate is the average of weather situation in a particular area, which affects all parts of ecosystem. Due to industrialization and urbanization, forests are cutting down and converted into living societies. This change in ecosystem disturbs the balance of ecosystem from decomposers to producers and consumers. Important part of ecosystem is plants (producers) that are energy providers. This alteration affects productivity and sustainability of plants. Wheat is staple food, which is highly affected by temperature and CO2 elevation. It not only affects wheat yield but also make wheat vulnerable to several diseases. High temperature causes a high rate of transpiration, which causes drought that ultimately leads to low productivity. A model was designed on drought conditions and result showed that global warming causes serious drought in 60% of wheat-growing areas of the world. Currently, drought affects 15% of wheat productivity. It was predicted that every 2°C shift of temperature can cause severe water shortage in the coming 20 to 30 years. Water shortage at milking and grain filling stage will affect yield. This chapter includes factors affecting climate, impact on wheat growth, yield, and elevation of carbon dioxide, impact on disease severity, prediction model for temperature rise, and CO2 curve in 2050.
Transgenic Technology Can Accelerate Cotton Breeding: Transgenic ScALDH21 Cotton Significantly Improve Drought Tolerance in Southern and Northern Xinjiang
Authors: Yang Honglan , Zhang Dawei , A. Bozorov Tohir , Waheed Abdul , Wang Jiancheng , Li Xiaoshuang , Daoyuan Zhang
Published: April 2022

Aldehyde dehydrogenases (ALDHs) contribute to cellular protection against oxidative stress. These enzymes are crucial to organisms’ ability to cope with environmental stress. The ALDH21 gene was introduced into upland cotton (Gossypium hirsutum L.) from desiccant-tolerant Syntrichia caninervis moss, created stable genetic transgenic lines. As a result, drought tolerance is increased and yield penalty is reduced in those transgenic lines. The first study to demonstrate overexpression of ALDH21 enhances drought tolerance in cotton under multi-location field experiments is presented here. Cotton genotypes containing ScALDH21 exhibit significant morphological, physiological, and economic benefits. ScALDH21 functions in the physiology of cotton plants to protect them by scavenging ROS and reducing osmotic stress. The yield of transgenic cotton in northern Xinjiang showed up to 10% improvement under full irrigation and up to 18% improvement in deficit irrigation conditions on fields with purple clay loam soils. Additionally, transgenic cotton can be grown in sandy loam soil in southern Xinjiang with an average yield increase of 40% on different irrigation levels in the desert-oasis ecotone. Using ScALDH21 as a candidate gene for cotton improvement in arid and semi-arid regions was demonstrated. In addition, we assessed different irrigation protocols and optimized irrigation methods with minimal water requirements for ScALDH21-transgenic cotton that could be used in production agriculture.
Smoking and the Association with Mental Health
Authors: Mahamud Isse Abdihakim
Published: April 2022

Tobacco use is the largest single cause of preventable mortality and morbidity worldwide and it is strongly associated with a variety of mental illnesses. Smoking is considered as a modifiable risk factor that has a significant impact on physical health, including lung diseases, cardiovascular disease, peptic ulcer disease, reproductive problems, and diminishment of bone minerals. Additionally, smoking is a major global public health issue and mortality is estimated to be around 6 million people per year. The prevalence of smoking in people with mental illness can range from 50 to 85%, and they are much less likely to quit smoking compared to the general population. Nicotine addiction plays a significant role in the maintenance of smoking in people with mental illnesses. Hence, it is important to encourage smoking cessation to reduce the health risk of smoking. In terms of smoking intervention, international guidelines recommend to treat smoking both pharmacological and with behavioral support in mentally ill patients. Furthermore, prevention strategies are also essential to control the harm of smoking at the public and individual levels. This chapter will highlight the effect of smoking and nicotine dependence among people with mental illness and their therapeutic policies to enhance the understanding of prevention and management of tobacco use as well as nicotine dependence.
Sleep Quality and Depression: Does Diabetes Mellitus Affect the Association in Older Patients?
Authors: Kheirkhah Farzan , Alishah Morvarid , Bayani Mohammad Ali , Hosseini Seyed Reza , Ghadimi Reza , Bijani Ali , Moudi Sussan
Published: April 2022

Background: Sleep quality and depression in late adulthood, especially in patients with diabetes mellitus (DM), may affect quality of life and active ageing. Objectives: This research aimed to examine the association between sleep quality, depression, and DM in older adults. Methods: This case-control study is performed on people aged 60 years and over living in Amirkola, north of Iran. Participants were divided into two equal groups randomly, based on DM's status. Sleep quality was assessed using the Pittsburgh sleep quality index, and depression was evaluated using the Geriatric Depression Scale. Results: Totally, 800 older adults were examined. The results showed that in both groups, with or without DM, people with depression had poorer sleep quality (P < 0.001). Logistic regression analysis revealed the significant effect of female gender (OR = 2.36; 95% CI: 1.70 - 3.27) and depression (OR = 1.85; 95% CI: 1.37 - 2.51) on sleep quality of older adults (P < 0.001). Conclusions: Older people with or without diabetes were more likely to present poor sleep if they had depression, and DM didn’t significantly affect sleep quality.
Coil Embolization of a Pseudoaneurysm of the Petrous Internal Carotid Artery Presenting with Otorrhagia: A Case Report and Review of the Literature
Authors: Hosseinzadeh Ahmad , Rasekhi AliReza , Borhani-Haghighi Afshin , Asnaashari Majid , Abdollahifard Saeed , Moein Seyed Arman
Published: April 2022

Introduction: Otorrhagia is not a common manifestation of petrous internal carotid artery (ICA) aneurysm. Besides idiopathic cases, different etiologies, including trauma, infection, and radiation, have been suggested for petrous ICA aneurysms/pseudoaneurysms. However, there is limited experience in the management of this rare aneurysm/pseudoaneurysm with coil embolization. Case Presentation: A 58-year-old man, who was a known case of chronic otitis media, was referred from the otorhinolaryngology ward with intractable bleeding from the right ear. A pseudoaneurysmal lesion (7 mm × 5 mm) was detected in the petrous segment of the internal carotid artery. The patient underwent coil embolization with no complications. Conclusion: To the best of our knowledge, this is the first case of petrous ICA pseudoaneurysm, presenting with only intractable otorrhagia. The patient was successfully treated with coil embolization, with no need for further interventions. Besides, a review of petrous ICA aneurysms or pseudoaneurysms presenting with otorrhagia was performed.
A Structural Equation Modeling Analysis of the Related Factors of Sexual Function and Dyspareunia After Vaginal Birth
Authors: Beheshtinasab Maryam , Rahimi Farinaz , Dabagh Fekri Samaneh , Moridi Azam , Roozbeh Nasibeh , Olfati Fatemeh , Molaei Maryam , Banaei Mojdeh
Published: April 2022

Background: According to the importance of postpartum sexual dysfunctions and their effects of these cases on the quality of life of the couple, this study aimed to determine vaginal postpartum sexual function and dyspareunia. Methods: This descriptive-analytical study was performed on 400 women with a history of natural childbirth in 2020 - 2021 in Hormozgan Province, Iran. The demographic and obstetric checklist, sexual function, and postpartum dyspareunia questionnaires (Carol Scale) were used. For data analysis, “SPSS 18.0” Software and for Partial least squares (PLS) modeling, Smart PLS Software was used. Results: The mean age of the women was 26.74 ± 6.12 years, and the average overall sexual function and postpartum dyspareunia score were 27.18 ± 8.62. All amounts of cross-validated communality indicated the appropriate and acceptable quality of the present research model. The absolute goodness of fit (GOF) for the tested model was 0.41, indicating the tested model's appropriate fit. Age, spouse age, education, the average number of intercourse, and marital satisfaction directly affected sexual function after vaginal birth. In contrast, age, spouse age, education, duration of marriage were indirectly correlated with sexual function after vaginal birth through marital satisfaction (P < 0.01). In the present study, age, spouse, and education had a direct and indirect effect on sexual function after vaginal birth. Conclusions: Poor marital satisfaction can cause sexual dysfunction after vaginal delivery. Therefore, it is hoped that by using the present study results and similar ones to identify the factors affecting sexual function, by training couples and healthcare providers, sexual relations and emotional performance between couples will be established and strengthened more than before.
ensino de filosofia sob o controle da concepção de competências na BNCC
Authors: Soares Helton Lima , Brício Vilma Nonato de
Published: April 2022

O presente artigo objetiva investigar o ensino de filosofia no contexto da Lei nº 13.415/17 e da Base Nacional Comum Curricular (BNCC), em especial da concepção neoliberal que carregam, expressada a partir da ideologia da competência. O artigo esboça, primeiramente, um breve histórico das decisões legais que interferiram no status curricular da filosofia desde a Ditadura Militar, em seguida analisa a BNCC e sua organização a partir da ideia competências e, finalmente, o que restou ao ensino de filosofia nesse cenário. Por meio da revisão bibliográfica e da análise documental, concluímos que a complexidade do campo filosófico não é contemplada na BNCC e sua organização por competências, uma vez que esta busca especialização e instrumentalização, e aquela pensamento crítico, reflexivo, radical e totalizante.
Association between metabolic syndrome and homocysteinemia in ischemic stroke
Authors: Vujnić Milorad , Prtina Alma , Milivojac Tatjana
Published: April 2022

Introduction. Stroke is one of the leading causes of morbidity and mortality worldwide. The relationship between metabolic syndrome (MetS) and homocysteinemia (Hcy) as risk factors for ischemic stroke (IS) is not completely clear. The aim of the study was to determine the frequency of MetS, serum level of Hcy and the frequency of hyperhomocysteinemia (HHcy), as well as their association in patients with IS. Methods. The research included 53 subjects being in rehabilitation after IS and 40 subjects in the control group in rehabilitation due to the back pain problems aged 50-70 years. The diagnosis of the ischemic stroke was established by insight in the medical documentation. All subjects had to have a diagnosis of stroke confirmed by imaging (CT or MR of the endocranium). All subjects in the control group were excluded from the existence of previous stroke, myocardial infarction, angina pectoris and peripheral vascular disease. MetS was defined according to the joint statement from 2009. Results. The frequency of MetS was significantly higher in patients with IS compared to the control group (88.7% vs. 70.0%, p<0.05). The level of Hcy and the frequency of HHcy were increased in the patients with stroke compared to the control group (15.0±5.50 µmol/L vs. 11.2±2.51 µmol/L, p<0.01 and 39.2% vs. 11.4%, p<0.01, respectively). Among patients with IS, those with MetS had higher frequency of HHcy (42.2% vs. 16.7%, p<0.05) and it increased with more individual components of MetS (11.1% in patients with 3 components, 36.8% in patients with 4 components and 64.7% in patients with 5 components, p<0.05). Hcy was also in positive correlation with serum triglyceride level. Conclusion. Our results suggest that MetS and Hcy represent a significant risk factors for IS. It seems that there is an association between these risk factors in pathogenesis of the IS, but further analyses are needed to confirm this hypothesis.
Acute surgical abdomen due to duodenal perforation in an elderly COVID-19 patient
Authors: Detanac Džemail , Zogić Enes , Bihorac Džemil , Detanac Dženana , Ćeranić Lejla , Mujdragić Mehmed , Alihodžić Kemal , Ćorović Irfan
Published: April 2022

Introduction. Since the announcement of the SARS-CoV-2 pandemic, the health system has been facing great challenges. Due to several uncertainties and concerns, surgeons face a huge challenge in solving urgent surgical conditions in order to save a life. Case report. We present a patient with a coronavirus (COVID-19) infection and acute abdomen who was in poor general condition at the time of surgery, septic, all as a result of duodenal ulcer perforation. She did not have a positive RT-PCR at the time of surgery, but the lung CT scan showed highly indicative signs of COVID-19 infection. She had a positive nasopharyngeal swab RT-PCR test for the SARS-CoV-2 virus on the first postoperative day. Conclusion. All suspected COVID-19 patients during surgery should be treated as positive for SARS-CoV-2 virus with the use of all staff protection measures.
Unapređivanje hemijske pismenosti učenika osnovnih škola kroz kontekstualni pristup obradi nastavne jedinice Alkani
Authors: Putica Katarina , Ralević Lidija
Published: April 2022

Organic chemistry represents an essential part of everyday life, but previous research indicates that traditional organic chemistry teaching, which focuses on the transmission of academic content, insufficiently promotes the development of pupils' chemical literacy in this field. Since context-based teaching approach has the potential to improve scientific literacy, in order to compare the effectiveness of the aforementioned teaching approaches in terms of developing elementary school pupils' chemical literacy in the field of organic chemistry, a pedagogical experiment with parallel groups was conducted. The experiment was organized within the elaboration of the teaching unit Alkanes and it encompassed 148 eighth-grade elementary school pupils (76 pupils in the experimental and 72 pupils in the control group). Through the elaboration of the content about alkanes, pupils develop chemical literacy in regard to the structure and nomenclature of these compounds, their physical and chemical properties and oil and its derivatives as energy sources, as well as environmental pollutants. Upon the elaboration of the abovementioned teaching unit, the experimental group achieved a significantly higher overall percentage of correct answers on the test that checked the development of pupils' chemical literacy in regard to alkanes on all three levels (knowledge, application and reasoning), which implies that context-based teaching approach could significantly enhance elementary school pupils' chemical literacy, in the field of organic chemistry.
Estimation of profitability factors of mill companies in Vojvodina
Authors: Tekić Dragana , Mutavdžić Beba , Milić Dragan , Novaković Tihomir , Popov Milana , Mihajlov Zlata
Published: April 2022

The subject of this research is mill companies that operated on the territory of Vojvodina in 2019. The aim of the research is to assess the profitability of the observed companies, as well as financial indicators that affect profitability. A sample of 23 small and medium-sized mills was taken and profitability indicators were calculated: return on assets and return on capital, as well as financial indicators: liquidity, indebtedness, solvency and productivity. Based on the calculated indicators of descriptive statistics, it was determined that the median value of the return on assets was 2.58%, and the median value of the return on capital was 5.56%. The influence of factors on profitability was analyzed by applying regression analysis, and the return on assets and return on capital appeared as dependent variables in the models. The significance of the formed regression models was tested by applying regression variance analysis and it was determined that the model containing the return on assets as a depended variable is statistically significant, while the model containing the return on capital as a dependent variable is not statistically significant. Of the observed profitability factors, only the indebtedness indicator stood out as significant.
Assessment of seed quality of different cabbage lots during aging
Authors: Poštić Dobrivoj , Štrbanović Ratibor , Broćić Zoran , Tabaković Marijenka , Đurić Nenad , Pavlović Nenad , Stanisavljević Rade
Published: April 2022

The aim of the research was to evaluate the influence of the year and the seed lots on the most important indicators of cabbage seed quality. Quality testing of nine different seed lots of Potomac F1 cabbage was performed during three years (2019, 2020 and 2021). Analyses of variance showed a significant effect (p<0.01) of the year (Y), while seed lot (L) and their interaction (Y × L) showed a significant effect (p<0.05) on all observed parameters quality (germination energy, total germination, abnormal seedlings and dead seeds). The strongest correlation between the examined parameters was in the first year and weakened in the second and third years. In the first year as expected, significant positive correlation between germination energy and total germination was found (r = 0.84779, p<0.01). The highly and negative interdependence was achieved between total germination and dead seeds (r = - 0.94363, p<0.001) and abnormal seedlings (r = -0.78019, p<0.05). Also negative interdependence was found between germination energy and dead seeds (r = -0.80000, p<0.01) and abnormal seedlings (r = -0.66144, p<0.05). The germination energy and the total germination of the cabbage seeds considered were found to decrease with the increasing seed age, in contrast to the numbers of their abnormal seedlings and dead seeds which continued to increase with seed aging. The obtained results indicate that the germination of highly hybrid conventional cabbage seeds decreases significantly during aging, as a direct consequence of a very significant increase in the number of abnormal seedlings.
Optimization of anthocyanins extraction process from black soybean seed coat for the preparation of maize-based functional food
Authors: Nikolić Valentina , Žilic Slađana , Simić Marijana , Perić Vesna , Srdić Jelena , Vasić Marko
Published: April 2022

Black soybean seed coat has a considerable content of anthocyanins which can provide a positive effect on the health of the consumers through food products enriched with the extracts of these valuable bioactive compounds. Nevertheless, the use of soybean seed coat, a by-product from soybean processing, additionally valorizes this raw material. The possibility of enrichment of sweet maize grains with anthocyanin extract was investigated. Several procedures with acetic acid were applied in the experiments of anthocyanins extraction from black soybean seed coat. During the marination process, the grains were stained, changing their standard yellow color to a crimson red. Since the brines with the addition of citric acid became cloudy (opalescent) after some time, lactic acid was used as an anthocyanin stabilizer in the continuation of the research. Depending on the extraction conditions, the spectrophotometrically determined content of total anthocyanins in the solution varied from 3541.90 to 5387.70 mg CGE/g d.m., and in the marinated maize grain between 179.89 and 286.05 mg CGE/g d.m. After seven days, the total anthocyanin content in the grain did not increase significantly, so this aging period was selected as optimal for marinating maize products.
Applying a non-parametric efficiency analysis to evaluate farm economic viability
Authors: Miljatović Aleksandar , Vukoje Veljko , Tekić Dragana
Published: April 2022

The aim of this research is to investigate technical efficiency in different types of farming in Republic of Serbia and then to determine achieved level of farm economic viability. The research is based on FADN data from 2020 year. An input-oriented data envelopment analysis method with variable return to scale is used for calculating farm technical efficiency. One output and four input variables are used in the model. Research has shown that farm technical efficiency in Serbia is on relatively low level (0.346). This indicates that there are significant reserves for potentially input reduction, without output reducing. According to types of farming the most efficient farms are the ones involved in horticulture production (0.542), followed by granivores (0.458) and vineyards and fruits (0.433), while the least efficient are dairy production (0.292). It is noticeable that more intensive types of farming have better output-input ratio, which indicates that those farms reached higher economic viability level. Of course, farm economic viability is wider term and further research should be directed at one comprehensive farm economic viability analysis which would take into consideration other relevant productivity indicators as well as profitability, liquidity and stability indicators. Thereby, considering FADN base limitations that are particularly noticeable when calculate liquidity and stability indicators, is necessary to continuously work on data quality improvement and to make the whole system better.
INTEGRATIVE POTENTIAL OF PROJECT ACTIVITIES IN FRENCH LANGUAGE TEACHING AT THE UNIVERSITY
Authors:   Kaluga State University named after K.E. Tsiolkovsky, Gorgarova Ya.Yu.
Published: April 2022

The article deals with the topical problem of implementation of students’ project activities in the process of learning in higher education. Based on the retrospective analysis of the project method formation in the world pedagogical theory and practice, employers’ requirements to university graduates as well as taking into consideration motivational and value characteristics of the modern youth generation, the author comes to the conclusion about the effectiveness of project technologies in forming key competences of a future specialist in the field of teaching foreign languages and presents her own algorithm of project work in French classes.
INFORMATION COMMUNICATION TECHNOLOGIES IN TEACHING ASTRONOMY IN PROFESSIONAL EDUCATION ORGANIZATIONS
Authors:   International Institute of Design and Service, Kondakov S.A. , Degterenko L.N.
Published: April 2022

The problem of using information communication technologies in teaching astronomy in professional education organizations is actualized. Classification of internet resources and specialized software in astronomy is considered, that can be used in the conditions of educational process informatization. Results of a pedagogical experiment aimed at studying the impact of the used internet resources and specialized software on student’s performance are presented. It has been found that application of modern communication technologies and specialized software makes it possible to imitate various processes and phenomena when studying the Universe, making the process of teaching astronomy exiting, interesting, absorbing and increases the motivation to studies and knowledge acquisition.
ACADEMIC CLASSES: CLUSTER INTEGRATION OF SOCIAL PARTNERS
Authors:   Academic Lyceum №. 95 of Chelyabinsk, Emelyanova L.A. , Glazyrina L.A. , Tatyanchenko D.V.
Published: April 2022

The article clarifies and concretizes the postulates of project management in the format of a general education organization. The main positions of the strategic vision of academic classes, characteristics of the content and organization of the technological profile of training with an engineering focus are presented. Special attention is paid to the creation and development of a territorial and multi-sectoral educational and career guidance cluster.
Flexible use of memory by food-caching birds
Authors: Applegate Marissa C , Aronov Dmitriy
Published: April 2022

Animals use memory-guided and memory-independent strategies to make navigational decisions. Disentangling the contribution of these strategies to navigation is critical for understanding how memory influences behavioral output. To address this issue, we studied spatial behaviors of the chickadee, a food-caching bird. Chickadees hide food in concealed, scattered locations and retrieve their caches later in time. We designed an apparatus that allows birds to cache and retrieve food at many sites while navigating in a laboratory arena. This apparatus enabled automated tracking of behavioral variables – including caches, retrievals, and investigations of different sites. We built probabilistic models to fit these behavioral data using a combination of mnemonic and non-mnemonic factors. We found that chickadees use some navigational strategies that are independent of cache memories, including opportunistic foraging and spatial biases. They combine these strategies with spatially precise memories of which sites contain caches and which sites they have previously checked. A single memory of site contents is used in a context-dependent manner: during caching chickadees avoid sites that contain food, while during retrieval they instead preferentially access occupied sites. Our approach is a powerful way to investigate navigational decisions in a natural behavior, including flexible contributions of memory to these decisions.
Opioid analgesia alters corticospinal coupling along the descending pain system in healthy participants
Authors: Tinnermann Alexandra , Sprenger Christian , Büchel Christian
Published: April 2022

Opioids are potent analgesic drugs with widespread cortical, subcortical, and spinal targets. In particular, the central pain system comprising ascending and descending pain pathways has high opioid receptor densities and is thus crucial for opioid analgesia. Here, we investigated the effects of the opioid remifentanil in a large sample (n = 78) of healthy male participants using combined corticospinal functional MRI. This approach offers the possibility to measure BOLD responses simultaneously in the brain and spinal cord, allowing us to investigate the role of corticospinal coupling in opioid analgesia. Our data show that opioids altered activity in regions involved in pain processing such as somatosensory regions, including the spinal cord and pain modulation such as prefrontal regions. Moreover, coupling strength along the descending pain system, that is, between the anterior cingulate cortex, periaqueductal gray, and spinal cord, was stronger in participants who reported stronger analgesia during opioid treatment while participants that received saline showed reduced coupling when experiencing less pain. These results indicate that coupling along the descending pain pathway is a potential mechanism of opioid analgesia and can differentiate between opioid analgesia and unspecific reductions in pain such as habituation.
The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus
Authors: Puri Natasha M , Romano Giovanna R , Lin Ting-Yu , Mai Quynh N , Irannejad Roshanak
Published: April 2022

Dopamine is a key catecholamine in the brain and kidney, where it is involved in a number of physiological functions such as locomotion, cognition, emotion, endocrine regulation, and renal function. As a membrane-impermeant hormone and neurotransmitter, dopamine is thought to signal by binding and activating dopamine receptors, members of the G protein coupled receptor (GPCR) family, only on the plasma membrane. Here, using novel nanobody-based biosensors, we demonstrate for the first time that the dopamine D1 receptor (D1DR), the primary mediator of dopaminergic signaling in the brain and kidney, not only functions on the plasma membrane but becomes activated at the Golgi apparatus in the presence of its ligand. We present evidence that activation of the Golgi pool of D1DR is dependent on organic cation transporter 2 (OCT2), a dopamine transporter, providing an explanation for how the membrane-impermeant dopamine accesses subcellular pools of D1DR. We further demonstrate that dopamine activates Golgi-D1DR in murine striatal medium spiny neurons, and this activity depends on OCT2 function. We also introduce a new approach to selectively interrogate compartmentalized D1DR signaling by inhibiting Gαs coupling using a nanobody-based chemical recruitment system. Using this strategy, we show that Golgi-localized D1DRs regulate cAMP production and mediate local protein kinase A activation. Together, our data suggest that spatially compartmentalized signaling hubs are previously unappreciated regulatory aspects of D1DR signaling. Our data provide further evidence for the role of transporters in regulating subcellular GPCR activity.
Zebrafish airinemes optimize their shape between ballistic and diffusive search
Authors: Park Sohyeon , Kim Hyunjoong , Wang Yi , Eom Dae Seok , Allard Jun
Published: April 2022

In addition to diffusive signals, cells in tissue also communicate via long, thin cellular protrusions, such as airinemes in zebrafish. Before establishing communication, cellular protrusions must find their target cell. Here, we demonstrate that the shapes of airinemes in zebrafish are consistent with a finite persistent random walk model. The probability of contacting the target cell is maximized for a balance between ballistic search (straight) and diffusive search (highly curved, random). We find that the curvature of airinemes in zebrafish, extracted from live-cell microscopy, is approximately the same value as the optimum in the simple persistent random walk model. We also explore the ability of the target cell to infer direction of the airineme’s source, finding that there is a theoretical trade-off between search optimality and directional information. This provides a framework to characterize the shape, and performance objectives, of non-canonical cellular protrusions in general.
Evaluation of commercially-available conductive filaments for 3D printing flexible circuits on paper
Authors: Jangid Aditya R. , Strong E. Brandon , Chuang Jacqueline , Martinez Andres W. , Martinez Nathaniel W.
Published: April 2022

Three commercially-available conductive filaments were evaluated for 3D printing flexible circuits on paper. While all three filaments were printed successfully, the resulting conductive traces were found to have significantly different impedances when characterized by electrochemical impedance spectroscopy. Using a graphite-doped polylactic acid filament, the flexibility of paper-based conductive traces was evaluated, methods of integrating common electrical and electronic components with the conductive traces were demonstrated, and the resistive heating of the traces was characterized. The ability to 3D print conductive traces on paper using commercially available materials opens many opportunities for rapid prototyping of flexible electronics and for integrating electronic circuits with paper-based microfluidic devices.
A DNA barcode survey of insect biodiversity in Pakistan
Authors: Ashfaq Muhammad , Khan Arif M. , Rasool Akhtar , Akhtar Saleem , Nazir Naila , Ahmed Nazeer , Manzoor Farkhanda , Sones Jayme , Perez Kate , Sarwar Ghulam , Khan Azhar A. , Akhter Muhammad , Saeed Shafqat , Sultana Riffat , Tahir Hafiz Muhammad , Rafi Muhammad A. , Iftikhar Romana , Naseem Muhammad Tayyib , Masood Mariyam , Tufail Muhammad , Kumar Santosh , Afzal Sabila , McKeown Jaclyn , Samejo Ahmed Ali , Khaliq Imran , D’Souza Michelle L. , Mansoor Shahid , Hebert Paul D. N.
Published: April 2022

Although Pakistan has rich biodiversity, many groups are poorly known, particularly insects. To address this gap, we employed DNA barcoding to survey its insect diversity. Specimens obtained through diverse collecting methods at 1,858 sites across Pakistan from 2010–2019 were examined for sequence variation in the 658 bp barcode region of the cytochrome c oxidase 1 (COI) gene. Sequences from nearly 49,000 specimens were assigned to 6,590 Barcode Index Numbers (BINs), a proxy for species, and most (88%) also possessed a representative image on the Barcode of Life Data System (BOLD). By coupling morphological inspections with barcode matches on BOLD, every BIN was assigned to an order (19) and most (99.8%) were placed to a family (362). However, just 40% of the BINs were assigned to a genus (1,375) and 21% to a species (1,364). Five orders (Coleoptera, Diptera, Hemiptera, Hymenoptera, Lepidoptera) accounted for 92% of the specimens and BINs. More than half of the BINs (59%) are so far only known from Pakistan, but others have also been reported from Bangladesh (13%), India (12%), and China (8%). Representing the first DNA barcode survey of the insect fauna in any South Asian country, this study provides the foundation for a complete inventory of the insect fauna in Pakistan while also contributing to the global DNA barcode reference library.
Association between laryngopharyngeal reflux and obstructive sleep apnea in adults
Authors: Tamin Susyana , Siregar Dumasari , Hutauruk Syahrial Marsinta , Restuti Ratna Dwi , Rachmawati Elvie Zulka Kautzia , Bardosono Saptawati
Published: April 2022

Background

Obstructive sleep apnea syndrome (OSAS) and laryngopharyngeal reflux (LPR) have been found to coexist in the population. OSAS and LPR also share obesity as an important risk factor. However, the relationship between LPR and OSAS remains unclear. This study aimed to correlate LPR as measured by the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) with OSAS.

Methods

This cross-sectional study included sixty-four subjects who underwent anamnesis to complete the RSI and the Epworth Sleeping Scale (ESS). The subjects were then divided into the OSAS and non-OSAS groups based on the Apnea-Hypopnea Index (AHI) obtained through a polysomnography examination. Both groups underwent a flexible fiberoptic nasopharyngolaryngoscopy examination to determine the RFS. LPR was identified based on the RSI and RFS.

Results

The mean BMI of the OSAS group significantly was higher than the non-OSAS group (p < 0.05). Most of the subjects in the OSAS group exhibited mild-moderate OSAS (AHI 10–29), and severe OSAS occurred in only seven subjects. The mean RSI and RFS values in the OSAS group did not differ significantly from the non-OSAS group (p = 0.34 and p = 0.36, respectively). The proportion of LPR between the mild-moderate OSAS group, the severe OSAS group, and the non-OSAS group did not differ significantly (p = 1.00). RSI and RFS did not significantly correlate with AHI. Based on RSI, the proportion of LPR between the ESS (+) and ESS (-) groups did not significantly differ (adjusted p = 0.062). The proportion of LPR based on RFS was almost equal between the ESS (+) and ESS (-) groups (p = 0.817).

Conclusions

The BMI of the OSAS group was significantly higher than the non-OSAS group. There was no significant difference in RSI and RFS between the OSAS and non-OSAS groups. There was no significant correlation between RSI and AHI, or between RFS and AHI. There was no significant difference in the proportion of RSI between the ESS (+) and the ESS (-) groups.
A Content and Thematic Analysis of Student International Internship Reports: Basis for Designing Alternative Experiential Learning Activities
Authors: Remanente Maria Cecilia
Published: April 2022

Schools design internship programs based on intended learning outcomes, which influence their choice of partner training establishments and setting of training activities and duration. An internship is a form of experiential learning, students acquire many unintended discoveries in completing their tasks and interacting with others. This study examines such intended and incidental learning experiences through content and thematic analysis of the internship reports of 26 students of a higher education institution (HEI) located in Cavite, Philippines, who joined either the Thailand Student Internship Abroad Program (SIAP) or the USA Work and Travel Program in 2018 and 2019. These reports contained student reflections, weekly logs of their training activities, and supervisor feedback. The following nodes or units of analysis were used: type of establishment, training area, intentional learning, incidental learning, courses and activities in school that prepared them for their internship, and the supervisors’ comments on the students’ performance. The findings highlight the importance of developing students’ skills in guest handling, food preparation and styling, guiding and escorting, report preparation, and event coordination in preparation for internship. Further, increased cultural knowledge and sensitivity was needed. These findings were used to improve the HEI internship and skills enhancement program for school year 2021-2022, tempered by current situations, most notably the SIAP suspension and limited implementation of onsite local practicum.  Alternative experiential learning activities were thus proposed.