bluuebunny/crossref_metadata_2025 huggingface dataset:
Studies on heterosis, correlation and genetic advance parameters for seed yield and its related traits in Indian mustard [Brassica juncea (L.) Czern and Coss.]
Authors: MOHD SALMAN  , MAHAK SINGH  , HARSHIT TRIPATHI  , PAWAN KUMAR  , SWAPNIL DWIVEDI  , SURENDRA KUMAR  , R P VYAS
Published: November 2023

Twenty eight genotypes (21 F1 + 7 parents) of Indian mustard were evaluated for 10 traits viz., days to 50% flowering, days to maturity, plant height (cm), length of main raceme (cm), number of siliquae/plant, number of primary branches/plant, number of secondary branches/plant, oil content (%), 1000-seed weight (g) and seed yield/plant (g). Analysis of variance revealed that the genotypes differed genetically for all the characters and thus has helped in selection of parents for the breeding programmes.
Genotype x environment interaction through AMMI analysis in sesame genotypes
Authors: BHAGWAT SINGH  , RAJANI BISEN
Published: November 2023

The present study investigates the magnitude of GxE interaction and stability of sesame genotypes over theenvironments. The results indicated that for seed yield/plant, the ASV values ranged from 0.186 to 2.363. Accordingly, genotypes SAVITRI, TMV-4, SSD-5, DSS-9 and RAJESHWARI were considered to be most stable, while YLM-17, CHANDANA, NIRMALA, USHA and PT-1 were less stable genotypes.
Effect of lime and FYM on growth, yield and quality of soybean (Glycine max) grown in acid soils of Nagaland
Authors: A K SINGH  , A O ENGRALA  , AVINIE NAKHRO
Published: November 2023

The experiment was conducted during kharif season for three years to assess the impact of lime and FYM onsoybean. Application of lime and FYM enhanced grain yield by 79% and 33%, respectively over control. Similar trend was observed with respect to haulm yield, oil content, protein content and nutrient NPK uptake.
Foliar application of water soluble fertilizers in summer groundnut in a Vertisols
Authors: B S YEANGI  , ROOPA  , U IRAMMA GOUDAR  , P NAGARAJU
Published: November 2023

A field experiment was carried out during summer season to know the effect of water soluble fertilizers on theperformance of groundnut (cv. TAG 24) in Vertisols of Northern Transition Zone of Karnataka. Application of FYM+ 100% RDF + foliar spray of fertilizers at 30, 45 and 60 days after sowing (DAS) recorded 7.35% higher pod yieldover application of 100% RDF and was on par with the treatment receiving FYM + 85 % RDF + foliar spray offertilizers at 30, 45 and 60 DAS and recorded the highest B:C ratio.
Conversion of castor shell into a value added compost
Authors: S K SHAH  , A L JAT  , A M PATEL  , D K PATEL  , D N TEJAN  , A G DESAI
Published: November 2023

Castor shell is rich in lignin material and takes a long time to decompose. Therefore, it is necessary evolveprocedures that can hasten this process so that the shell could be used as compost. The compost heaps were prepared in four treatment combinations (T1: castor shell + 10% dung slurry; T2: castor shell + dung slurry + 2% urea solution + 0.5% SSP; T3: castor shell + dung slurry + microbial consortium @ 1 kg/t; and T4: castor shell + dung slurry + 2% urea solution + 0.5% SSP + microbial consortium @ 1 kg/t. The N (1.2%) and P (1.4%) in T4, and K (1.5%) T1 were maximum. Micronutrients, Fe (4000 ppm) in T3 and Zn (68 ppm) in T4 were maximum.
Effect of imposed terminal drought on yield, yield attributing traits and aflatoxin contamination in groundnut (Arachis hypogea L.)
Authors: HASANALI NADAF  , G CHANDRASHEKHARA  , B N HARISH BABU
Published: November 2023

Sixty six genotypes of groundnut were screened under drought stress conditions. Yield, yield attributes andaflatoxin content were estimated at harvest. Reduction in yield and yield attributing traits, except for number of primary branches and amount of aflatoxin contamination under drought stress as compared to normal moisture condition, was observed.
Influence of soil moisture conservation practices and planting geometry on growth, yield and economics of safflower (Carthamus tinctorius L.)
Authors: KUMAR LAMANI  , G SOMANAGOUDA  , S R SALAKINKOP
Published: November 2023

A field experiment was conducted to study the influence of soil moisture conservation practices and plantinggeometry on growth, yield and economics of safflower under northern dry zone (Zone-3) of Karnataka. Tied ridges(1,061 kg/ha) and plant geometry of 45 x 20 cm (1,093 kg/ha) recorded significantly higher seed yield. Similar trendwas noticed with respect to gross returns and net returns.
Integration of pre and post-emergence herbicides for weed management in irrigated groundnut (Arachis hypogaea L.)
Authors: T PARTHIPAN
Published: November 2023

Field experiment was conducted during kharif 2018 to evaluate suitable integrated weed management practicesfor effective weed control in groundnut. Pre-emergence application of pendimethalin 30EC+imazethapyr 2EC (1.0kg/ha) followed by one manual weeding at 25-30 days after sowing recorded higher weed control efficiency and pod yield than other treatments.
Performance of castor (Ricinus communis L) hybrids and varieties under rainfed conditions in Alfisols
Authors: R MOHAN KUMAR  , YAMANURA
Published: November 2023

An experiment was conducted to study the performance of seven hybrids/varieties of castor for their adaptabilityand yield potentiality. GCH-8 recorded significantly higher seed yield of castor (2369 kg/ha) and was statisticallysuperior over rest of the cultivars. Seed yield of GCH-8 in each harvest was 961, 698 and 710 kg/ha at primary,secondary and tertiary spikes respectively.
Standardization of fertigation schedule for rabi castor (Ricinus communis L.) under drip irrigation
Authors: A V RAMANJANEYULU  , A MADHAVI  , M V NAGESH KUMAR  , T L NEELIMA  , M VENKATA RAMANA  , A SRINIVAS
Published: November 2023

Fertigation @ 30 kg N during 10-55 days after sowing (DAS); 40-50 kg N during 56-85 DAS; 20-30 kg N during86-115 DAS and 20 kg N/ha during 116-145 DAS resulted in significantly higher seed yield of castor (3351 to 3356kg/ha), higher water use efficiency (8.79-8.82 kg/ha/mm) and nitrogen use efficiency (27.9 kg/ha).
Mechanized cultivation in safflower (Carthamus tinctorius L.)
Authors: PRITAM O BHUTADA  , S B GHUGE  , S A SHINDE  , S V PAWAR
Published: November 2023

The un-replicated field experiment was conducted with two sets of treatments (mechanization and farmer'spractice) in safflower. Mechanized cultivation in safflower recorded significantly higher yield of safflower than farmer practice. The seed yield increase was 24% under mechanized condition than farmer's practice. Energyproductivity (kg/MJ) was higher (0.49) under mechanized cultivation compared to farmer's practice (0.28).
Role of seed age in screening for salt tolerance of sunflower at germination
Authors: LAKSHMI PRAYAGA  , P LAKSHMAMMA  , C SARADA
Published: November 2023

Three sunflower hybrid seeds of known age (3, 2 and 1 month old) seeds of DRSH-1, KBSH-44, CO-2respectively were tested for salt tolerance by conducting germination studies in 200, 250, 300, 350 mM NaCl atmonthly intervals. Results differed when seeds of same age were compared with seeds of mixed age. Therefore, for valid comparisons, the seeds should essentially be of same age.
Bayesian Inference and Simulation for Logarithm Transformed (LT) Method Using Stan
Authors: Mohammed H AbuJarad  , Eman AbuJarad  , Athar Ali Khan
Published: November 2023

In this article, the researchers set up one and two parameters life model called the Logarithm Transformed Exponential Distribution (LTE) and Logarithm Transformed Weibull Distribution (LTW). The researchers give extensive consequence of the survival function and hazard rate function. To fit this model as survival model and hazard rate function the researchers adopted to use Bayesian approach. A real survival data set is used to illustrate this work. Application is done by R and Stan, then a comparison of the two models is conducted by using LOO package to find the best model and simulation. R and Stan codes have been given to actualize censoring mechanism via optimization and also simulation tools.
Metaverse and its potential applications
Authors: Purushotham A Naga Sai , Pinisetti Swami Sairam
Published: November 2023

Metaverse is a community-owned online digital platform that enables augmented reality and virtual reality interaction between users. It does not belong to a single dealer and is not dependent on any specific hardware. The decentralized metaverse, that is supported by technologies like artificial intelligence (AI), computer vision, virtual reality, blockchain, etc., is made possible by digital currencies and NFTs. Users can create digital avatars that are representative of themselves to explore their environment by combining various technologies.

The concept of the metaverse has grown in popularity recently as 5G networks have developed a more fast and augmented reality (AR) and virtual reality (VR) technologies have been used more frequently. Because of the outbreak of COVID-19, which has made maximum number of individuals work from their homes, individuals are now greatly conscious of the fact that it may disrupt their day-to-day life. With all this at the place, adding to Facebook's latest entry in the market was observed by the investors and daily basis internet consumers throughout the world.
Effect of crude fibre additives ARBOCEL and VITACEL on the physicochemical properties of granulated feed mixtures for broiler chickens
Authors: Urban Jakub , Michalczuk Monika , Batorska Martyna , Marzec Agata , Jaroszek Adriana , Bień Damian
Published: November 2023

Objective: The aim of the study was to evaluate the physicochemical properties (nutrient composition, pH, water content and activity, sorption properties) and mechanical properties (compression force and energy) of granulated feed mixtures with various inclusion levels of crude fibre concentrates ARBOCEL and VITACEL for broiler chickens, i.e. +0.0% (control group - group C), +0.3%, +0.8%, +1.0%, +1.2%.Methods: The feed mixtures were analyzed for their physicochemical properties (nutrient composition by near-infrared spectroscopy, pH with the use a CP-401 pH meter with an IJ-44C glass electrode, water content was determined with the drying method and activity was determined with the Aqua Lab Series 3, sorption properties was determined with the static method) and mechanical properties (compression force and energy with the use TAHD plus texture analyzer). The Guggenheim-Anderson-de Boer (GAB) model applied in the study correctly described the sorption properties of the analyzed feed mixtures in terms of water activity.Results: The fibre concentrate type affected the specific surface area of the adsorbent and equilibrium water content in the GAB monolayer (p≤0.05) (significantly statistical). The type and dose of the fibre concentrate influenced the dimensionless C and k parameters of the GAB model related to the properties of the monolayer and multilayers, respectively (p≤0.05). They also affected the pH value of the analyzed feed mixtures (p≤0.05). In addition, crude fibre type influenced water activity (p≤0.05) as well as compression energy (J) and compression force (N) (p≤0.001) (highly significantly statistical) of the feed mixtures.Conclusion: The physicochemical analyses of feed mixtures with various inclusion levels (0.3%, 0.8%, 1.0%, 1.2%) of crude fiber concentrates ARBOCEL or VITACEL demonstrated that both crude fiber types may be used in the feed industry as a feedstuff material to produce starter type mixtures for broiler chickens.
Effect of pre-slaughter fasting time on carcass yield, blood parameters and meat quality in broilers
Authors: Wu Xuezhuang , Zhou Yahao , Lu Zhentao , Zhang Yunting , Zhang Tietao
Published: November 2023

Objective: The aim of this study was to evaluate the effect of pre-slaughter fasting time on carcass yield, meat quality, blood parameters and glucose metabolism in broilers.Methods: Four hundred and fifty Arbor Acres (AA) broilers at 42 days of age were divided into 5 groups with 6 replicates in each group and 15 chickens as one replicate. Following this period, broilers from each group were distributed among five groups according to preslaughter fasting period as 4, 8, 12, 16, or 20 h.Results: With increasing fasting time, the carcass yield (p<0.01), the breast muscles yield (p<0.01) and the thigh yield (p<0.01) of the broilers were all linearly increased. With increasing fasting time, the L* values (p<0.01), cooking loss (p = 0.020), moisture content (p<0.01) in the leg muscles linearly downregulated, while the drip loss (p = 0.043), pH45 min (p<0.01) and pH24 h (p<0.01) were linearly upregulated. A trend for a lower (p = 0.071) shear force in the leg muscles was also observed in broilers fasted for longer time. Similar results were also found in breast muscles. The different fasting treatments did not influence the breast muscles glycogen content (p>0.10), while the increase of fasting time resulted in a linear decrease of the blood glucose (p = 0.021) and, more specifically, the glycogen content of the liver and leg muscles (p<0.001). With increasing fasting time, the aspartate transaminase (p<0.01), uric acid (p<0.01), and triglycerides (p<0.01) in serum linearly downregulated, while the alanine aminotransferase was linearly upregulated.Conclusion: The results of this study show a significant influence of fasting time on carcass yield and meat quality in broilers. Moderate fasting (8 to 12 h) before slaughter can reduce the weight loss of broilers. Prolonged fasting (≥16 h) increased body weight loss, decreased slaughtering performance and fluctuating blood indexes of broilers.
Carcass characteristics, meat quality, sensory palatability and chemical composition of Thai native cattle grazing in lowland and Phu Phan mountain forest
Authors: Gunun Nirawan , Kaewpila Chatchai , Suwannasing Rattikan , Khota Waroon , Khejornsart Pichad , Phoemchalard Chirasak , Laorodphan Norakamol , Kesorn Piyawit , Gunun Pongsatorn
Published: November 2023

Objective: The aim of this study was to assess the effect of Thai native cattle grazing in the lowland or mountain forest on carcass characteristics, meat quality, sensory palatability, and chemical composition.Methods: Twelve male Thai native cattle with an average weight of 110±10 kg are allowed to be grazing in the lowland or Phu Phan mountain forest during the rainy season in northeastern Thailand.Results: The carcass characteristics, meat pH, and meat color were unaffected by treatment (p>0.05). The boiling loss was lower in the cattle grazing on the mountain forest (p = 0.027). The cattle grazing in the mountain forest had increased shear force (p = 0.039), tenderness (p = 0.011), and flavor intensity (p = 0.003). The protein and fat were higher (p<0.001 and p = 0.035, respectively) in cattle grazing in the mountain forest. The different grazing systems of the cattle had no effect (p>0.05) fatty acids in meat, except for capric acid (C10:0) and lauric acid (C12:0), which were higher (p = 0.046 and p = 0.049, respectively) when the cattle were grazing in the mountain forest. The different grazing systems did not influence (p>0.05) the unsaturated fatty acids in meat.Conclusion: Thai native cattle grazing in the Phu Phan mountain forest in the rainy season improves meat quality, sensory evaluation, and chemical composition.
Roman Medan: Analisis Potret Sosial dalam Karya Sastra Masa Revolusi Indonesia di Sumatera Timur, 1945-1949
Authors: Utari Melly Tria
Published: November 2023

This article aims to elucidate the role of the literary work "Roman Medan" in depicting the socio-historical landscape of the Indonesian Revolution in East Sumatra. Employing a historical methodology and a social history approach, this research leverages various written sources, including "Roman Medan" stories published during the Indonesian Revolution era, newspapers, and supplementary literature. Despite the pervasive turmoil during the Revolution, authors and prominent figures did not remain silent; they endeavored to navigate through armed conflicts and diplomatic channels. In the context of East Sumatra, these efforts culminated in the creation of "Roman Medan." Unfortunately, these literary works have received limited attention, even though "Roman Medan" constitutes an authentic cultural product of the local community, offering profound insights into the lives of the people. The findings underscore that the conditions prevailing during the Revolution provided literary inspiration for authors. Through "Roman Medan" they conveyed the spirit of nationalism and offered a glimpse into the daily lives of individuals during this transformative period. Consequently, "Roman Medan" serves as a valuable resource for understanding the social realities of the Indonesian Revolution in East Sumatra.
Analisis Uji Beda Gaya Hidup Mahasiswa Urban dan Rural Terhadap Perubahan Perilaku di Fakultas Kedokteran Universitas Prima Indonesia
Authors: Nasution Zahrah Fadhilla , Gusbakti Rusip  , Fiska Maya Wardhani
Published: November 2023

This research aims to examine the influence of urban and rural backgrounds on the lifestyle choices and behavioral changes among medical students. The study addresses the question of how different backgrounds shape the students' lifestyles and behavioral patterns. A quantitative approach was employed, involving a sample of 100 medical students (50 from urban areas and 50 from rural areas). Data were collected through a questionnaire and analyzed using a t-test to compare the differences between the two groups. The findings indicate significant variations in lifestyle choices and behavioral changes between urban and rural medical students, with rural students exhibiting higher levels of consumerism and more pronounced behavioral shifts. The study concludes that the students' urban or rural backgrounds play a crucial role in shaping their lifestyles and behaviors, emphasizing the need for contextual considerations in educational interventions and support systems.
Peningkatan Kemampuan Membaca Pemahaman Menggunakan Metode SQ3R pada Siswa SMK Kahuripan 1 Jakarta
Authors: Sembiring Anjelita , Sjafei Irna
Published: November 2023

There are two aims of this research, namely: 1) describing the procedures for development learning using the SQ3R method which can improve abilities students' reading comprehension, 2) there is an increase in reading ability students' understanding using the SQ3R method. This type of research is qualitative descriptive. The data source in this research is the informant, namely the teacher Indonesian language class XII SMK Kahuripan 1 Jakarta, namely Mrs. Laili Lufti Yuli, S. Pd and class XII students. The data is in the form of an increase in reading ability understanding using the SQ3R method in students at SMK Kahuripan 1 Jakarta. Data collection techniques in this research are interviews, student observation, tests/performance, and and using questionnaires. Characteristic analysis techniques qualitative. Research results regarding improving reading ability understanding using the SQ3R method in students at SMK  Kahuripan 1 Jakarta divided into three, namely: 1) increasing students' liking for language lessons Indonesia, 2) increase in reading comprehension ability results, 3) increase student activities in learning Indonesian.
Effectiveness and Safety After a Switch to Tildrakizumab: A Real World Multicenter Italian Study in Psoriasis
Authors: Di Brizzi Eugenia Veronica , Buononato Dario , Benvenuto Pierfrancesco , Argenziano Giuseppe , De Pasquale Rocco , Fiorella Carmen Silvia , Gioffrè Claudia , Musumeci Maria Letizia , Palazzo Giovanni , Zichichi Leonardo , Balato Anna
Published: November 2023

Introduction: Tildrakizumab is a humanized IgG1κ monoclonal antibody targeting the p19 subunit of interleukin (IL)-23, approved in 2018 for the treatment of patients with moderate-to-severe chronic plaque psoriasis.

Objectives: This study aimed to evaluate the effectiveness, safety and survival of tildrakizumab in the medium term (48 weeks) in psoriatic patients failure to previous biologic treatment in a real world setting.

Methods: This was a retrospective, multicenter observational study that included adult patients with moderate-to-severe plaque psoriasis, failure to previous biologic therapy, consecutively treated with tildrakizumab. PASI and BSA values were recorded at baseline, at 12 and 48 weeks of treatment. Safety and tolerability of tildrakizumab were investigated by examining the presence of any adverse events.

Results: Overall 51 patients were enrolled. Baseline disease severity was moderate to severe with a mean PASI score of 19.2 ± 8.5, mean BSA of 16 ± 10.4, and mean DLQI of 18.2 ± 6.8. A significant reduction in the mean PASI score was detected at 12 weeks of tildrakizumab therapy (3.5 ± 2.7, p < 0.001), with a further improvement at week 48 (0.6 ± 1.5, p < 0.001). At week 12, there was a great improvement in BSA score for all groups (p <0.001) with further increase at week 48. The effectiveness was confirmed also by DLQI assessment, with a significant decrease at week 12 and even more at week 48 (p <0.001).

Conclusions: This study confirms the effectiveness of tildrakizumab in daily clinical practice in patients with moderate-to-severe plaque psoriasis.
Asuhan Keperawatan Ny. N dengan Gangguan Persepsi Sensori: Halusinasi Pendengaran Di Ruang Dewi Kunti RSJ Prof Dr. Soerojo Magelang
Authors: Rodini Rodini , Thoyibah Thoyibah
Published: November 2023

Halusinasi merupakan suatu gejala gangguan jiwa di mana klien merasakan suatu stimulus yang sebenarnya tidak ada. Klien mengalami perubahan sensoripersepsi; merasakan sensasi palsuberupa suara, penglihatan, pengecapan, perabaan, atau penciuman. Pada gangguan halusinasi penglihatan misalnya, klien melihatsuatu bayangan menakutkan, padahal tidak ada bayangan tersebut. Salah satumanifestasi yang timbul adalah halusinasi membuat klien tidak dapat memenuhi kehidupannya sehari-hari. Halusinasi merupakan salah satu dari sekian bentuk psikopatologi yang paling parah dan membingungkan. Secara fenomenologis, halusinasi adalah gangguan yang paling umum dan paling penting. Selain itu, halusinasi dianggap sebagai karakteristik psikosis. Cukup tingginya jumlah klien yang dirawat dengan masalah utama Gangguan Halusinasi Pendengaran di Rumah Sakit Jiwa Prof Dr Soerojo Magelang yaitu bulan Agustus 2020 – Desember 2020, maka dibutuhkan perawat untuk melakukan asuhan keperawatan dengan memperhatikan aspek bio-psikososial-kultur dan spiritual, merupakan hal pokok yang melatar belakangi penulis mengambil kasus Gangguan Halusinasi Pendengaran. Tujuan dari penulisan Laporan Studi Kasus ini adalah memperoleh pengalaman nyata dalam merawat atau melakukan asuhan keperawatan pada klien dengan Halusinasi Pendengaran dengan menggunakan tahap-tahap proses keperawatan. Metode yang digunakan dalam penulisan Laporan Studi Kasus ini menggunakan metode deskriptif yaitu wawancara, observasi, study dokumentasi dan literatur. Diagnosa keperawatan yang didapat yaitu Halusinasi Pendengaran. Untuk dapat mencapai hasil yang optimal bisa dicapai yaitu apabila proses keperawatan dilakukan secara komprehensif yang ditunjang oleh adanya kerja sama dengan klien, keluarga, perawat dan tim kesehatan lainnya sehingga apa yang diharapkan bisa tercapai
Counterfactual Probability
Authors: Schultheis Ginger ,   Journal of Philosophy Inc.
Published: November 2023

Stalnaker’s Thesis about indicative conditionals says, roughly, that the probability one ought to assign to an indicative conditional is equal to the probability that one ought to assign to its consequent conditional on its antecedent. Skyrms’s Thesis about counterfactual conditionals says, roughly, that the probability that one ought to assign to a counterfactual conditional equals one’s rational expectation of the chance, at a relevant past time, of its consequent conditional on its antecedent. In this article, I develop a new uniform theory of conditionals that allows us to derive a tenable version of Skyrms’s Thesis from a tenable version of Stalnaker’s Thesis, together with a chance-deference relating rational credence to beliefs about objective chance.
Interview with Ned Block, New York University
Authors: Block Ned ,   The Yale Philosophy Review
Published: November 2023

Professor Block has written extensively on a number of topics in the philosophy of mind, from consciousness to cognitive science, and is particularly known for his work on Functionalism. Many of his papers are collected in Consciousness, Functionalism, and Representation (2007). This interview was conducted in New Haven on March 6th, 2007.
Cox10 Novel Variant in a Lebanese Female Patient with Congenital Cataracts
Authors:   Department of Pediatrics, Neurometabolic Unit, Saint George University Medical Center, Lebanon., Ghassan HMAIMESS , Ghewa EL-ACHKAR ,   Faculty of Medicine, Saint George University of Beirut, Lebanon., Naji HAMOUCHE ,   Department of Pediatrics, Neurometabolic Unit, Saint George University Medical Center, Lebanon., Marie-Therese EID ,   Department of Pediatrics, Neurometabolic Unit, Saint George University Medical Center, Lebanon., Aimee ABI SAAB ,   Faculty of Medicine, Saint George University of Beirut, Lebanon., Pierre HAGE ,   Department of Pediatrics, Neurometabolic Unit, Saint George University Medical Center, Lebanon., Andre MEGARBANE ,   Department of Human Genetics, Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Lebanon., Mamdouha BARMADA ,   Neuromuscular Pathology department, American University of Beirut, Lebanon., Hicham MANSOUR ,   Department of Pediatrics, Neurometabolic Unit, Saint George University Medical  Center, Lebanon.
Published: November 2023

Mitochondrial disorders can present with a very wide clinical variability depending on the affected gene. Novel mutations in mitochondrial diseases are being identified more frequently than the past decades in the Lebanese population, where these disorders rank as the most common inborn errors of metabolism. Here we describe a novel COX10 variant in a female patient from south Lebanon, presenting with congenital cataracts, failure to thrive, microcephaly, global developmental delay and behavioral problems. The patient carries a not reported before missense mutation in the COX10 gene (c.514A>G p.(Thr172Ala)), confirming the diagnosis of a homozygous COX10 variant, in favor of Leigh syndrome The cataracts finding. This is to our knowledge the first reported patient with COX10 mutation presenting with congenital cataracts; thus, adding to the clinical spectrum of this disease.
Application of molecular methods in optimizing clinical management of patients with pulmonary multidrug resistant tuberculosis in Tanzania
Authors:   , Mbelele Peter
Published: November 2023

Rifampicin or multidrug-resistant tuberculosis (RR/MDR-TB) accounts for considerable morbidity and mortality. Differences among Mycobacterium tuberculosis complex (MTBC) species may predict drug-resistance or treatment success. This thesis aimed at identifying MTBC at species level, their drug-resistance patterns, and mycobactericidal effect of different regimens in patients treated for RR/MDR-TB and drug-susceptible (DS-TB). This was a cross sectional study nested in a longitudinal design that followed patients on RR/MDR-TB and DS TB treatment for 4 months. While RR/MDR-TB patients received bedaquiline with or without an injectable-aminoglycoside based regimen, DS-TB patients received a fixed-dose combination comprised of rifampicin-isoniazid-pyrazinamid-ethambutol (RHZE). The genotype MTBC assay was used to identify MTBC species. WGS-based drug resistant mutations predicted the minimum-inhibitory-concentration (MIC) of antibiotics measured in the MycoTB-Sensitire™ assay. An isolate was categorised as resistant and susceptible if it had a MIC above and at or below the epidemiological-cut-off (ECOFF) value, respectively. Non linear-mixed effects modelled the MTBC killing rates measured by Tuberculosis molecular bacterial load assay and culture. The median MIC at their 25th and 75th interquartile range (IQR) were compared using Mann-Whitney U test. Among 126 patients, 89 (71%) had positive culture whereas 87 (98%) were identified as M. tuberculosis. Overall, mutant (gNWT-R) MTBC isolates correlated with MIC values above the ECOFF. For instance, the median MIC (µg/mL) for rifampicin-gNWT-R strains was > 4.0 (IQR; 4.0 – 4.0) compared to 0.5 (IQR; 0.38 – 0.50) in non-mutant (gWT-S, p < 0.001); isoniazid-gNWT-R > 4.0 (IQR; 2.0 – 4.0) compared to 0.25 (IQR; 0.12 – 1.00) among gWT-S (p = 0.001); ethionamide-gNWT-R 15.0 (IQR; 10.0 – 20.0) compared to 2.50 (IQR; 2.50 – 5.00) among gWT-S (p < 0.001). There were no detectable mutations in genes previously known to confer fluoroquinolones, aminoglycosides, capreomycin, bedaquiline, delamanid, linezolid, clofazimine, cycloserine, and p aminosalicylic acid resistance. Compared to the adjusted M. tuberculosis killing rate of -0.17 (95% CI; -0.23 to -0.12) for the injectable without bedaquiline reference regimen, the killing rates were -0.62 (95% CI; -1.05 to -0.20) log10 eCFU/mL for the injectable with bedaquiline containing regimen (p = 0.019), -0.35 (95% CI; -0.65 to -0.13) log10 eCFU/mL for the all-oral bedaquiline-based regimen (p = 0.054), and -0.29 (95% CI; -0.78 to +0.22) log10 eCFU/mL for RHZE (p = 0.332). The detected M. tuberculosis was susceptible to core drugs including bedaquiline, fluoroquinolones, linezolid, and clofazimine, supporting their central use in the RR/MDRTB treatment regimens. M. tuberculosis killing rates were higher among patients who received bedaquiline but were further improved with addition of an injectable aminoglycoside.
The Correlation Of Medication Adherence In Patients With Type 2 Diabetes And The Incident Of Hypertension In Primary Health Care Setting
Authors:   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Boy Elman , Hasibuan Risky Ananda ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Hanifah Aqilah ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Oktavanny Eka Retning ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Auliati Octari ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Yussuf Murrizaldy ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Muhammad Izza Sagi ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Yondhi Yondhi ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Fadmadani Anisa ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Ayuni Ceri Permata ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara, Efeliani Lifea ,   Medical Faculty Of Universitas Muhammadiyah Sumatera Utara
Published: November 2023

The global incidence and prevalence of type 2 diabetes mellitus has continued to increase over the past three decades and is expected to triple by 2030.1 Based on data from the World Health Organization (WHO), in 2021, 1.28 billion adults worldwide have hypertension.4 In relation to type 2 DM therapy, patient non-compliance in undergoing treatment can cause failure to control blood sugar levels and can cause cardiovascular complications.5 Objective: To determine the relationship between adherence to medication consumption in people with type 2 diabetes mellitus and the incidence of hypertension. Methods: This study used an analytical descriptive method with cross sectional design. Sampling used consecutive sampling techniques with the sample size obtained using the Slovin formula, where the population was 447, resulting in a total sample of 218 respondents who made the inclusion and exclusion criteria. Primary data was obtained from the Medication Adherence Rating Scale-10 (MARS-10) questionnaire which was filled in by the respondent and the respondent’s blood pressure was checked by automatic sphygmomanometer Kenz AC-05P. Data was analyzed using SPSS-25 software with the chi- square test. Results: From 218 respondents, 80 respondents were non-adherent in taking medication and suffered from hypertension (90.9%) and 8 respondents were non-adherent in taking medication and did not suffer from hypertension (9.1%). There were 29 respondents who adhered to taking medication and suffered from hypertension (22.3%) and 101 respondents who adhered to taking medication and did not suffer from hypertension (77.7%). These results obtained a p-value of 0.000 <0.05, which means there is a relationship between adherence to drug consumption in patients with type 2 diabetes mellitus and the incidence of hypertension. Conclusion: There is a relationship between adherence to drug consumption in patients with type 2 diabetes mellitus and the occurrence of hypertension at Puskesmas Sentosa Baru and Puskesmas Sering in Medan City.
Pengaruh Faktor Lingkungan terhadap Eksplorasi Sumber Daya Alam dan Perubahan Iklim
Authors: Judijanto Loso , Yusuf Ramdan , Abdillah Rizky
Published: November 2023

Penelitian ini menyelidiki jaringan hubungan yang rumit antara faktor lingkungan, eksplorasi sumber daya alam, dan perubahan iklim di Indonesia. Penelitian ini menyelidiki peran faktor geologi, topografi, dan iklim dalam membentuk kegiatan eksplorasi sumber daya alam dan dampaknya terhadap lingkungan. Melalui analisis kuantitatif dan kualitatif, penelitian ini mengungkapkan bahwa faktor-faktor lingkungan ini secara signifikan mempengaruhi kelayakan, biaya, dan keberlanjutan proyek-proyek eksplorasi. Selain itu, studi ini juga menggarisbawahi kontribusi substansial dari eksplorasi sumber daya, khususnya industri batubara dan minyak, terhadap emisi gas rumah kaca dan deforestasi. Meskipun Indonesia telah memperkenalkan berbagai kebijakan dan inisiatif untuk mengurangi dampak lingkungan, tantangan dalam penegakan hukum dan kepatuhan masih ada. Temuan penelitian ini menekankan perlunya transisi menuju sumber energi yang lebih bersih dan kerangka kerja peraturan yang lebih kuat untuk mengatasi tantangan lingkungan yang ditimbulkan oleh eksplorasi sumber daya alam di Indonesia. Penelitian ini memberikan wawasan penting bagi para pembuat kebijakan, pemangku kepentingan industri, dan pendukung lingkungan hidup yang berusaha menyeimbangkan pembangunan ekonomi dengan pelestarian lingkungan hidup.
The Influence of Social Media Influencers on Generation Z Consumer Behavior in Indonesia
Authors: Erwin Erwin , Saununu Siska Jeanete , Rukmana Arief Yanto
Published: November 2023

Through a quantitative approach, this study examines how social media influencers affect Indonesian Generation Z consumer behavior. A heterogeneous group of 450 participants, ranging in age from 16 to 24, was involved, reflecting a range of genders, socioeconomic backgrounds, and geographic locations. The results show that social media influencers have a big influence on people's decisions to buy, as 85% of participants acknowledged. The majority platform, Instagram, accounted for 75% of the total, with individuals using social media for two hours a day on average. The most popular content categories (65%) were product and lifestyle reviews, highlighting the significance of authenticity. Transparency (72.5%) and authenticity (67.5%) were important trust-building qualities; on the other hand, inconsistent brand endorsements (30%) and a lack of financial transparency (22.5%) eroded confidence. Sponsored material worked very well (80%), and 60 percent of users preferred partnerships that were authentic. Strong positive correlations between sponsored content, consumer behavior, and influencer engagement were found via regression analysis (R-squared = 0.754). The findings offer significant perspectives for marketers seeking to maneuver through the impactful terrain of Generation Z in Indonesia.
Existence and uniqueness of weak solutions to parabolic problems with nonstandard growth and cross diffusion
Authors: Arumugam Gurusamy , Erhardt Andre H.
Published: November 2023

We establish the existence and uniqueness of weak solutions to the parabolic system with nonstandard growth condition and cross diffusion, $$\displaylines{ \partial_tu-\text{div}a(x,t,\nabla u)) =\text{div}|F|^{p(x,t)-2}F),\cr \partial_tv-\text{div}a(x,t,\nabla v))=\delta\Delta u, }$$ where \(\delta\ge0\) and \(\partial_tu,~\partial_tv\) denote the partial derivative of u and v with respect to the time variable t, while \(\nabla u\) and \(\nabla v\) denote the one with respect to the spatial variable x. Moreover, the vector field \(a(x,t,\cdot)\) satisfies certain nonstandard p(x,t) growth, monotonicity and coercivity conditions.

For more information see https://ejde.math.txstate.edu/Volumes/2020/123/abstr.html
Global solutions for fractional viscoelastic equations with logarithmic nonlinearities
Authors: Cabanillas Lapa Eugenio
Published: November 2023

In this article we study a fractional viscoelastic equation of Kirchhoff type with logarithmic nonlinearities. Under suitable conditions we prove the existence of global solutions and the exponential decay of the energy.

For more information see https://ejde.math.txstate.edu/Volumes/2020/125/abstr.html
Kant and Analysis
Authors: Lewin Michael , Williamson Timothy
Published: November 2023

In the current dialogue between two authors with different views on analysis, philosophy, and the use of labels, the leading question is: How should one understand the expression ‘analytic philosophy’? Lewin argues that as there are no generally agreed tenets and methods of what is being called ‘analytic philosophy’, the name is to be replaced by a more specific one or abandoned. Williamson defends the use of this phrase, claiming that it is quite serviceable, as it relates to a broad tradition of influence, while it is not even required to adhere to the method of analysis in any distinctive sense. Lewin counters that, in this case, ‘analytic philosophy’ is too empty. One could heal this by conceptual analysis of ‘analytic philosophy’ — but then Kant, for whom philosophy is inherently analytic, would be a proponent of analytic philosophy. Another option is to follow Ryle’s ideal of a label-free, coherent and honest thinking. As Lewin argues, Williamson’s views seem at least partially to agree with Kant’s conception of the difference between philosophy and history of philosophy as well as empirical analysis and the underlying empirical realism. Williamson replies that he uses ‘analytic philosophy’ in its current meaning, which is not composed of the meanings of ‘analytic’ and ‘philosophy’. The current use is different from the earlier ones and not applicable to Kant. He argues against the transcendental idealism and the coarse-grained distinction between analytic and synthetic and a priori and a posteriori that requires an update.
Kant als metaphilosophischer Skeptizist?
Authors: Minkin Daniel
Published: November 2023

Throughout history, both philosophers and non-philosophers have doubted that philosophical positions qua philosophical positions are justified and that philosophy is a rational enterprise. Today, such doubts are grouped under the term “Metaphilosophical Skepticism”. Nicholas Rescher, in his book Strife of Systems, includes Kant among the proponents of this kind of skepticism. I want to argue that while Rescher is wrong, Kant has con­tributed to a new version of such skepticism. In the first step, I characterize the basic idea of metaphilosophical skepticism in more detail and identify a version of this idea, which I call “Second-Stage-Skepticism” and on which I will focus. In the following part, I reconstruct Rescher’s reading of Second-Stage-Skepticism as well as his reasons for considering Kant to represent this version. My main claim in this part will be that there is no reading of the mentioned basic idea that makes Rescher’s view reasonable. In the third step, I introduce a newer form of metaphilosophical skepticism — “Third-Stage Skepticism” — and conjecture that this form can be seen as inspired by Kant’s thought on philosophical diversity. Finally, I point out a way to reject this newer form.
Nghiên cứu lớp phủ bê tông siêu tính năng (UHPC) liên hợp bản mặt thép để sửa chữa mặt cầu Thăng Long
Authors: Trần Bá Việt , Lương Tiến Hùng
Published: November 2023

Thang Long bridge, after many years of operation with increasing traffic volume, leads to the steel face plate of the bridge not ensuring the conditions of stiffness and deflection within the allowable limit. After scientific conferences and experimental studies, it was shown that the solution "using Ultra High Performance Concrete (UHPC) technology associated with orthogonal steel decks to form composite lightweight deck slabs" design selection to repair Thang Long bridge deck. In order to successfully apply UHPC coating in this project, it is necessary to determine the technological parameters such as: flow, setting time, rheology and shrinkage according to actual construction conditions at site ( temperature and humidity). In addition, other physical and mechanical properties of UHPC must be determined such as compressive strength, tensile strength, elastic modulus and dry shrinkage. This study has determined the technological parameters for the construction of UHPC coating during the period from August 25, 2020 to December 31, 2020 to meet the technical requirements of the Thang Long bridge deck repair project.
INFLUÊNCIA DO ICMS ECOLÓGICO (ICMS-E) NAS DESPESAS COM SANEAMENTO
Authors: Santana Elivaldo Ribeiro de , Silva Ricardo Freitas da Silva , Duarte Júlio Cesar Messias Duarte , Sousa Vera Lúcia Cardoso de Sousa
Published: November 2023

O objetivo neste trabalho foi fazer uma análise comparativa dos gastos municipais em saneamento após sua inclusão como critério de repasse do ICMS-e no Estado de Mato Grosso do Sul. Foram utilizados dados dos gastos em saneamento de quarenta e sete municípios sul mato grossenses com área de cerrado superior a 50%. O recorte temporal foi de 2003 a 2017, a despesa agrupada em três intervalos de cinco anos (2003 a 2007; 2008 a 2012 e 2013 a 2017). O instrumento analítico utilizado foi o Teste t de Student para amostras independentes, com intervalo de confiança de 95%, ou seja, com um nível de confiança de 5% (p < 0,05). O Teste t de Student mostrou que existe diferença estatisticamente significativa na média do gasto público municipal com a função saneamento do período 2008 a 2012 em comparação ao período de 2013 a 2017 (t = -2,880 (gl = 4,357) e p = 0,041), resultado corroborado pelo estudo de Ferreira, et al., (2015). Essa evidência revela que existe a possibilidade de que o gasto municipal com saneamento seja influenciado por políticas públicas ambientais como o repasse diferenciado do ICMS-e. O resultado do Teste t dos dois períodos de cinco anos que antecedem a implementação do saneamento como critério de repasse do ICMS-e (2003 a 2007 e 2008 a 2012), não apresentou diferença estatisticamente significativa (t = -0,341 (gl = 8) e p = 0,742). Os dois períodos não são marcados por gastos municipais elevados na função saneamento, portanto, é natural que não haja grandes diferenças em suas médias.
EFEITOS DA PANDEMIA NA COLETA SELETIVA EM RIO VERDE - GO
Authors: Lopes Adriana , Pereira Luciane
Published: November 2023

O aumento dos riscos de contaminação pela COVID-19 é uma preocupação mundial, principalmente no ambiente urbano e suas interações. Os métodos de prevenção ainda encontram obstáculos e um dos fatores agravantes é a falta de conhecimento sobre o contágio, devido a doença ser recente. Um dos temas ainda pouco abordado é a destinação de resíduos sólidos e a propagação do vírus. Dentro deste contexto, há muitos questionamentos sobre como realizar adequadamente a coleta seletiva com segurança sanitária. O objetivo geral deste estudo foi analisar os efeitos da pandemia do coronavírus nas atividades da coleta seletiva no município de Rio Verde (GO). Os objetivos específicos foram: (a) investigar os procedimentos adotados pela população e pela cooperativa durante o período de isolamento social e (b) identificar as dificuldades encontradas na realidade atual (“novo normal”), bem como as consequências na produtividade da cooperativa. Para isso, foram analisadas pesquisas anteriores e realizadas entrevistas com o responsável pela cooperativa. Dentre os resultados, foi constatado o decréscimo na produtividade de coleta de materiais recicláveis, houve mudanças significativas na condução das atividades realizadas na cooperativa, estratégias foram estabelecidas para evitar a disseminação do novo coronavírus e parte dos primeiros casos foram encontrados em bairros circunvizinhos ao roteiro pré-estabelecido pela cooperativa.
Solidarity-Based Content Sharing on Social Media: A Closer Look at the Language Style among Millennial Social Platform Users
Authors: Saragih Mandra , Aisyaroh Yola Ayudi
Published: November 2023

Social Media platforms have shaped diverse linguistic issues through informal language use, language adaptation and change, linguistic creativity and global communication. The current study reveals the issues about investigating about language style and linguistic form of solidarity expression used by the millennial community on social media platforms. Thirty respondents who aged about 23-43 years old considered as millennial participated in this study and inquired through open-ended questionnaire.  The data was probed by using grounded theory proposed by Creswell. The findings exposed that language style were realized for certain communication purposes and based-social context oriented, solidarity expression was shown through a different linguistic form to reveal ideas, feeling, empathy, caring, respect, moral justice and kinds of arguments. after deeply investigated, there were four types of language styles that are dominantly used by millennial on this social media platform, namely formal language style, informal language style, slang language style and colloquial language style, unfortunately, many people abuse social media as a platform for venting their anger and their disappointment by using disrespectful language and behaviors are frequently observed online. Consequently, this scholarly paper also provides advice on the user of social media platform must possess a range of skills including linguistic knowledge, sociocultural knowledge, and the ability to use language in appropriate ways depending on the specific communicative context.
Educational Supervision: An Analysis of Models, Approaches, And Techniques of Educational Supervision in Higher Education
Authors: Nur Rochbani Ita Tryas , Nurdianingsih Fitri
Published: November 2023

This research aims to conduct research by applying descriptive analysis techniques using library research. Testing the validity of the data was carried out by triangulating the data from references, both in terms of method and in terms of sources.

The results of this research indicate that the implementation of educational supervision should not only be carried out by lecturers but also apply to the entire academic community, including education staff. The involvement of all components of the academic community through various models, approaches and techniques of educational supervision by lecturers, rectors, education staff, foundations, students, the community and government is very necessary for the progress of a higher education institution.