bluuebunny/crossref_metadata_2025 huggingface dataset:
Heavy-ion radiation-induced colitis and colorectal carcinogenesis in Il10-/- mice display co-activation of β-catenin and NF-κB signaling
Authors: Suman Shubhankar , Moon Bo-Hyun , Datta Kamal , Kallakury Bhaskar V. S. , Fornace Albert J.
Published: December 2022

Space radiation-induced gastrointestinal (GI) cancer risk models for future interplanetary astronauts are being developed that primarily rely on quantitative animal model studies to assess radiation-quality effects of heavy-ion space radiation exposure in relation to γ-rays. While current GI-cancer risk estimation efforts are focused on sporadic GI-cancer mouse models, emerging in-vivo data on heavy-ion radiation-induced long-term GI-inflammation are indicative of a higher but undetermined risk of GI-inflammation associated cancers, such as colitis-associated cancer (CAC). Therefore, we aimed to assess radiation quality effects on colonic inflammation, colon cancer incidence, and associated signaling events using an in-vivo CAC model i.e., Il10-/- mice. Male Il10-/- mice (8–10 weeks, n = 12/group) were irradiated with either sham, γ-rays or heavy-ions (28Si or 56Fe), and histopathological assessments for colitis and CAC were conducted at 2.5 months post-exposure. qPCR analysis for inflammation associated gene transcripts (Ptges and Tgfb1), and in-situ staining for markers of cell-proliferation (phospho-histone H3), oncogenesis (active-β-catenin, and cyclin D1), and inflammation (phospho-p65NF-κB, iNOS, and COX2) were performed. Significantly higher colitis and CAC frequency were noted after heavy-ion exposure, relative to γ and control mice. Higher CAC incidence after heavy-ion exposure was associated with greater activation of β-catenin and NF-κB signaling marked by induced expression of common downstream inflammatory (iNOS and COX2) and pro-proliferative (Cyclin D1) targets. In summary, IR-induced colitis and CAC incidence in Il10-/- mice depends on radiation quality and display co-activation of β-catenin and NF-κB signaling.
CCT6A knockdown suppresses osteosarcoma cell growth and Akt pathway activation in vitro
Authors: Zeng Weiquan , Wu Meizhu , Cheng Ying , Liu Liya , Han Yuying , Xie Qiurong , Li Jiapeng , Wei Lihui , Fang Yi , Chen Youqin , Peng Jun , Shen Aling
Published: December 2022

We assessed the role of the protein-coding gene chaperonin-containing TCP1 subunit 6A (CCT6A) in osteosarcoma, as this is currently unknown. Using data from the R2 online genomic analysis and visualization application, we found that CCT6A messenger ribonucleic acid (RNA) expression is increased in osteosarcoma tissue and cells. Transfection of CCT6A small interfering RNA into cultured osteosarcoma cells revealed that CCT6A knockdown attenuates cell growth, cell viability, cell survival, and induced apoptosis and cell cycle progression at the G0/G1 phases. Moreover, CCT6A knockdown downregulated phospho-protein kinase B (p-Akt), cyclinD1 and B-cell lymphoma-2, whereas upregulated Bcl-2-associated X-protein expression. Thus, CCT6A knockdown inhibits cell proliferation, induces cell apoptosis, and suppresses the Akt pathway.
Effect of SGLT-2 inhibitors on body composition in patients with type 2 diabetes mellitus: A meta-analysis of randomized controlled trials
Authors: Pan Runzhou , Zhang Yan , Wang Rongrong , Xu Yao , Ji Hong , Zhao Yongcai
Published: December 2022

Objective

Type 2 diabetes mellitus(T2DM) is closely related to sarcopenic obesity(SO). Body composition measurement including body weight, body mass index, waist circumference, percentage body fat, fat mass, muscle mass, visceral adipose tissue and subcutaneus adipose tissue, plays a key role in evaluating T2DM and SO. The weight reduction effect of sodium-glucose cotransporter 2(SGLT-2) inhibitors has been demonstrated. However, there are warnings that SGLT-2 inhibitors should be used with caution because they may increase the risk of sarcopenia. The effect of SGLT-2 inhibitors on body composition in T2DM is inconclusive. In this work, a meta-analysis of randomized controlled trials was conducted to evaluate the effect of SGLT-2 inhibitors on body composition in T2DM.

Methods

PubMed, the Cochrane Library, EMbase and Web of Science databases were searched by computer. All statistical analyses were carried out with Review Manager version 5. 3. Results were compared by weight mean difference(WMD), with 95% confidence intervals(CI) for continuous outcomes. A random effects model was applied regardless of heterogeneity. The I2statistic was applied to evaluate the heterogeneity of studies. Publication bias was assessed using Funnel plots.

Results

18 studies with 1430 participants were eligible for the meta-analysis. SGLT-2 inhibitors significantly reduced body weight(WMD:-2. 73kg, 95%CI: -3. 32 to -2. 13, p<0. 00001), body mass index(WMD:-1. 13kg/m2, 95%CI: -1. 77 to -0. 50, p = 0. 0005), waist circumference(WMD:-2. 20cm, 95%CI: -3. 81 to -0. 58, p = 0. 008), visceral fat area(MD:-14. 79cm2, 95%CI: -24. 65 to -4. 93, p = 0. 003), subcutaneous fat area(WMD:-23. 27cm2, 95% CI:-46. 44 to -0. 11, P = 0. 05), fat mass(WMD:-1. 16kg, 95%CI: -2. 01 to -0. 31, p = 0. 008), percentage body fat(WMD:-1. 50%, 95%CI:-2. 12 to -0. 87, P<0. 00001), lean mass(WMD:-0. 76kg, 95%CI:-1. 53 to 0. 01, P = 0. 05) and skeletal muscle mass(WMD:-1. 01kg, 95%CI:-1. 91 to -0. 11, P = 0. 03).

Conclusion

SGLT-2 inhibitors improve body composition in T2DM including body weight, body mass index, waist circumference, visceral fat area, subcutaneous fat area, percentage body fat and fat mass reduction, but cause adverse effects of reducing muscle mass. Therefore, until more evidence is obtained to support that SGLT-2 inhibitors increase the risk of sarcopenia, not only the benefit on body composition, but also the adverse effect of the reduction in muscle mass by SGLT-2 inhibitors in T2DM should be considered.
Listeria motility increases the efficiency of epithelial invasion during intestinal infection
Authors: Wortel Inge M. N. , Kim Seonyoung , Liu Annie Y. , Ibarra Enid C. , Miller Mark J.
Published: December 2022

Listeria monocytogenes (Lm) is a food-borne pathogen that causes severe bacterial gastroenteritis, with high rates of hospitalization and mortality. Lm is ubiquitous in soil, water and livestock, and can survive and proliferate at low temperatures. Following oral ingestion of contaminated food, Lm crosses the epithelium through intestinal goblet cells in a mechanism mediated by Lm InlA binding host E-cadherin. Importantly, human infections typically occur with Lm growing at or below room temperature, which is flagellated and motile. Even though many important human bacterial pathogens are flagellated, little is known regarding the effect of Lm motility on invasion and immune evasion.

Here, we used complementary imaging and computer modeling approaches to test the hypothesis that bacterial motility helps Lm locate and engage target cells permissive for invasion. Imaging explanted mouse and human intestine, we showed that Lm grown at room temperature uses motility to scan the epithelial surface and preferentially attach to target cells. Furthermore, we integrated quantitative parameters from our imaging experiments to construct a versatile “layered” cellular Potts model (L-CPM) that simulates host-pathogen dynamics. Simulated data are consistent with the hypothesis that bacterial motility enhances invasion by allowing bacteria to search the epithelial surface for their preferred invasion targets. Indeed, our model consistently predicts that motile bacteria invade twice as efficiently over the first hour of infection.

We also examined how bacterial motility affected interactions with host cellular immunity. In a mouse model of persistent infection, we found that neutrophils migrated to the apical surface of the epithelium 5 hours post infection and interacted with Lm. Yet in contrast to the view that neutrophils “hunt” for bacteria, we found that these interactions were driven by motility of Lm—which moved at least ~50x faster than neutrophils. Furthermore, our L-CPM predicts that motile bacteria maintain their invasion advantage even in the presence of host phagocytes, with the balance between invasion and phagocytosis governed almost entirely by bacterial motility. In conclusion, our simulations provide insight into host pathogen interaction dynamics at the intestinal epithelial barrier early during infection.
Greek doctors during the COVID-19 pandemic: Transnational migration or stasis?
Authors: Gkolfinopoulos Andreas , Krannich Sascha
Published: December 2022

In this article, we investigated how the pandemic actually influenced decisions of migration/mobility of highly skilled EU migrants. We took a closer look at physicians in Greece and Germany, because they can be seen as a very mobile migrant group, which is highly demanded by the labour market of the health industry as doctors in hospitals, clinics or universities in both countries and beyond. Based on the opposed theoretical concepts of ‘transnational mobility or migration’ and ‘stasis,’ we conducted in-depth interviews with selected Greek doctors before and during the COVID-19 pandemic. The results of this study indicate that the pandemic has mainly had little impact on the migration/mobility of interviewed Greek doctors. Rather, economic demand on the health market seems to be more important than the impact of the pandemic on mobility, long-term migration or stasis.
From ‘digital nomadism’ to ‘rooted digitalism’: The remote work and im/mobilities of IT professionals in times of COVID-19
Authors: Cangià Flavia , Wassmer Sabrine , Davoine Eric , Salamin Xavier
Published: December 2022

This article explores the interplay between digital work and mobility through a look at the career trajectories, remote work practices and im/mobilities of professionals in the information technology (IT) sector. We draw upon a qualitative study conducted with IT professionals who work remotely for Swiss or Swiss-based international companies. IT professionals have been pioneers in practising virtual work long before the outbreak of the COVID-19 crisis and have long engaged in various forms of mobility, including tourism and labour migration. A focus on their remote work and im/mobility practices can shed light on the possibilities and challenges of the virtualization of work, especially in the context of the pandemic. We discuss how geographical immobility, combined with digital technology, becomes important in building a career and a personal life, staying ‘rooted’ and reconstituting the boundaries between work and non-work.
Keeping calm and carrying on: International students in lockdown
Authors: Gomes Catherine
Published: December 2022

What has been the impact of COVID-19 lockdowns on international students and how have they coped with living, often in isolation, in a foreign country? This article examines the challenges and coping strategies of current and recently graduated higher degree by research (HDR) international students in the Australian city of Melbourne through a transient migration lens. Through interviews with eight international students during one of Melbourne’s lockdown periods, this pilot study provided participants the opportunity to explain that not only were they dealing with the difficulties posed by lockdowns (e.g., loneliness and lack of sense of belonging) but doing so while balancing non-lockdown-related issues as students and transient migrants (e.g., passing their degree courses). Students interviewed however also revealed that they made the most out of lockdowns while taking charge of their own well-being by working towards their postgraduate futures and using the time to discover new non-study-related talents (e.g., watercolouring). The results of this study provide international education stakeholders and higher education institutions with ways of moving forward in the student support space.
A qualitative study of international students’ sexual health information behaviours: The case of Chinese men who have sex with men
Authors: Chang Shanton , Kuang Peng , Trumpour Sabrina
Published: December 2022

There has been an increase in HIV diagnoses among Chinese men who have sex with men international students (CMISs) in Australia. However, there is not a lot of understanding about the sexual health information of this cohort of transient students. There are often assumptions of low sexual health literacy and other vulnerabilities made about this cohort, but the actual cultural and systemic barriers are not well understood. In particular, there is a lack of understanding about their sexual health information behaviours. Data were collected through semi-structured in-depth interviews among ten CMISs in Australia, recruited from social dating apps and snowballing methods. Within this sample, there was a diversity in CMISs’ prior sexual health knowledge, sources of sexual health information and engagement with the Australian LGBTIQA+ community. A key concern amongst those interviewed was a lack of in-depth knowledge about the Australian health system. This article challenges some of the assumptions about CMISs’ sexual health information behaviours and calls for a more nuanced approach when engaging with them. In order to provide relevant and timely sexual health information to CMISs, these results point to four areas for attention and improvement. These are use of peer mentoring, messaging disseminated through Chinese social media, activating a more inclusive LGBTIQA+ community and increasing awareness about the Australian health system.
Digital Experiences of International Students: Challenging Assumptions and Rethinking Engagement, Shanton Chang and Catherine Gomes (eds) (2021)
Authors: Zhao Xinyu (Andy)
Published: December 2022

Review of: Digital Experiences of International Students: Challenging Assumptions and Rethinking Engagement, Shanton Chang and Catherine Gomes (eds) (2021)

Abingdon and New York: Routledge, 228 pp.,

ISBN 978-0-36722-635-0, p/bk, £34.99
Experimental studies of linear quadratic regulator (LQR) cost matrices weighting to control an accurate take-off position of bicopter unmanned aerial vehicles (UAVs)
Authors: Prakosa Jalu Ahmad , Wang Hai , Kurniawan Edi , Agmal Swivano , Kholili Muhammad Jauhar
Published: December 2022

Controller design for airplane flight control is challenged to achieve an optimum result, particularly for safety purposes. The experiment evaluated the linear quadratic regulator (LQR) method to research the optimal gain of proportional-integral-derivative (PID) to hover accurately the bicopter model by minimizing error. The 3 degree of freedom (DOF) helicopter facility is a suitable bicopter experimental simulator to test its complex multiple input multiple output (MIMO) flight control model to respond to the challenge of multipurpose drone control strategies. The art of LQR setting is how to search for appropriate cost matrices scaling to optimize results. This study aims to accurately optimize take-off position control of the bicopter model by investigating LQR cost matrices variation in actual experiments. From the experimental results of weighted matrix variation on the bicopter simulator, the proposed LQR method has been successfully applied to achieve asymptotic stability of roll angle, although it yielded a significant overshoot. Moreover, the overshoot errors had good linearity to weighting variation. Despite that, the implementation of cost matrices is limited in the real bicopter experiment, and there are appropriate values for achieving an optimal accuracy. Moreover, the unstable step response of the controlled angle occurred because of excessive weighting.
Numerical and experimental study of mixed flow pump as turbine for remote rural micro hydro power plant application
Authors: Mejiartono Sarid , Hikmawan Muhammad Fathul , Nugraha Aditya Sukma
Published: December 2022

The use of a pump as opposed to a turbine/pump as turbine (PAT) for off-grid electrification applications is one of the important ways to be considered in efforts to equalize electrical energy in Indonesia. The main problem in PAT applications is how to predict pump performance if applied as a turbine to find out its best characteristics and efficiency points. This study discusses a method to find pump performance specifications when using a pump with a mixed flow type as a turbine for Micro Hydro Power Plants. The numerical method by utilizing computational Fluid Dynamics (CFD) based software simulations that have been proven to be accurate according to previous studies was selected for use in obtaining predictions of the pump characteristics as turbines. Then the PAT characteristics of the CFD simulation results are validated by conducting direct testing. The results of the CFD numerical simulation using ANSYS Fluent software show the performance curve of a mixed flow pump operated as a turbine at various rotating speeds. The highest efficiency for each rotating speed ranges from 35-40%. The test results directly show the PAT characteristics, that the performance range is close to the numerical simulation results with a difference of 10%.
Effect of lightning mast placement on underground power cable jacket stress within high voltage substations
Authors: Nazih Mostafa
Published: December 2022

This study aims to investigate the impact of lightning masts placement on underground cables within high voltage substations. While the subject of lightning discharges near to underground cables has been covered with open cable runs and wind farms in many papers, this study focuses on lightning events within high voltage substations considering the associated effective zones, which were not covered in the available literature. Substations built within areas prone to high lightning activity experience frequent discharges that cause the potential rise of the earthing system into hundreds of kilovolts. The potentials propagating within the soil and the earthing grid affect underground cables jackets terminated within the substation. The numerical analysis of the problem is carried out using Current Distribution, Electromagnetic fields, Grounding and Soil structure analysis (CDEGS) software engine for different configurations of lightning mast placements with varied separation, electrode placement and length, soil resistivity, and lightning current. Study findings indicate that provision of lightning masts/down conductors as far as possible or at least twice the effective zone radius from cable termination/route electrodes ensures relatively lower stress voltages. Electrodes with effective zone radius length placed as close as possible to lightning masts further reduce the attainable jacket stress voltages.
Dewatering requirements assessment for the Central Kalimantan NCP open pit gold mine
Authors: Anatoly Nico , Rofikoh Siti
Published: December 2022

One of the most critical aspects of open pit mining is the dewatering and mine drainage systems. The NCP Open Pit Gold Mine is located in Central Kalimantan. This study area has a range of rainfall intensities and durations from moderate to heavy. Good dewatering is required to manage runoff water and reduce runoff from entering the pit and mine front loading. The study used daily rainfall intensity data from 1994 to 2018. Using the Mononobe Method, the hydrological data for this area were evaluated by determining the value of the rainfall intensity plan. According to the evaluation of rainfall data from 1994 to 2018, the research area saw a rainfall intensity of 86.23 mm/day over a two-year return period. The majority of water extracted from mines is from precipitation and runoff rather than groundwater. An open channel was made around the open pit, flowing water naturally into the sump to reduce water entering the mining area. The water was pumped into the settling pond with 520 m3/hour and 780 m3/hour capacity pumps.
AFTER 16 YEARS: AN UPDATE CHECKLIST OF HERPETOFAUNA ON THE NATUNA ISLANDS, INDONESIA
Authors: Herlambang Alamsyah E. N. , Riyanto Awal , Munir Misbahul , Hamidy Amir , Kimura Kaeda , Eto Koshiro , Mumpuni Mumpuni
Published: December 2022

Since the last list of amphibians and reptiles of the Natuna Islands was published nearly 20 years ago, here we provide an updated species list of the herpetofauna of these remote Indonesian islands. We compiled and summarized data from the available literature, and from our own studies conducted in 2011, 2012, 2013, 2017, and 2019. In total, 120 species of amphibians and reptiles were recorded for the Natuna Islands, which included 28 new records and six endemics. Over the past eight years, four species new to science were described from these islands, and they are: Cnemaspis mumpuniae, Cnemaspis sundainsula, Cyrtodactylus hikidai, and Cyrtodactylus rosichonariefi.
A CITIZEN SCIENCE CASE STUDY TO CHART INDONESIAN BIODIVERSITY: UPDATING THE DIVING BEETLE FAUNA OF BALI (COLEOPTERA: DYTISCIDAE)
Authors: Suprayitno Nano , Narakusumo Raden Pramesa , Sarino Sarino , Setyo Budi Anang , Hendrich Lars , Hájek Jiří , Balke Michael
Published: December 2022

We present new data on the geographical distribution of 16 species of diving beetles collected by an Indonesian citizen scientist in Bali. Copelatus oblitus Sharp, 1882, C. regimbarti Branden, 1884, C. sumbawensis Régimbart, 1899, and Hydroglyphus laeticulus (Sharp, 1882) are recorded for the first time from the island. We summarize what is known about the species’ distributions and habitats in Indonesia and beyond, and provide distribution maps and photographs of the sampling sites and habitus of the species. This work serves as a best practice template between individual local citizen scientists with local and international scientists.
Problems of Indexing in Documentation and Mapping of Rock Art Sites
Authors:   Higher School of Economics, Yu. Svoysky , I. Abolonkova ,   Kuzbass Museum-Reserve “Tomskaya Pisanitsa”, E. Levanova ,   Institute of Archaeology RAS
Published: December 2022

In early 21st century, there were a number of tendencies in the search for rock art, mainly due to the development of digital technologies. The development of documentation and analysis tools (mapping of sites using drones and GNSS receivers, digital photography, three-dimensional modeling of individual sites elements) allowed researchers to start a continuous (rather than a selective) process documentation on the new technological base, using elements of a system approach. The next stage of these studies, to the extent that the quality of the documentation is maintained, is to accumulate knowledge about rock art in geographical information systems and databases. However, existing indexing systems of sites do not withstand the new digital reality and, for various reasons, are not suitable for use in digital information systems. The article summarizes the experience of creation of indexing systems in the studies of the beginning of the 20th — beginning of the 21st century. The authors present the principles of “topographic” indexing system, based on ignoring semantics and chronological attribution of images and thus separating the documentation of rock art from its interpretation.
Archaeological Analogies to the Traditional Costume Elements in the Eastern Hindukush Area
Authors:   Russian State University for the Humanities, S. Yatsenko , S. Kaverin ,   Paleoethnology Research Center
Published: December 2022

The article analyzes 22 details of the costume of Kafirs and partially the Kalasha of Hindukush which have close analogies among related ancient Iranian-speaking peoples of Pre-Islamic time. The Indo-Scythians and Kushans, who created large powers nearby in the 1st c. BC — 1st c. AD, have the most of such analogies. These peoples had an impact on the clothing of the local Indo-Iranians and, probably, participated in their ethnic history. The infl uence of the ancient Iranian peoples, who lived closer to the Hindukush, manifested itself in large costume accessories, as well as in headdresses and hairstyles. It is also easy to explain the presence of similar elements in the “world empire” of the Achaemenids and among such an active people in the early Middle Ages as the Sogdians. However, many details of the costume of the somewhat isolated societies of the highlands with their simple rural life did not find analogies in the ceremonial art for the elite of various Iranian peoples. Collaboration between a cultural anthropologist and an archaeologist seems to be important to solve this problem. New methods of such joint research are proposed.
Dating of the Iron Buckles, Plaques on the Belt and Hooks of the Middle Ages Period from the Middle Volga Region (based on the Materials of the Ostolopovo Settlement in Tatarstan)
Authors:   Kazan State Institute of Culture, K. Rudenko
Published: December 2022

The article deals with iron buckles, plaques on the belt and hooks from the excavations of the Ostolopovo settlement in Tatarstan. It existed in the 11th — 12th centuries. The Ostolopovo settlement was one of the settlements in the central part of the Volga Bulgaria, located on the way from the center of the state to the Kama River, which was the most important trade route of Bulgaria. The settlement was investigated in 1969 and 1997–2013. It is distinguished by a unique stratigraphy, which is associated with the peculiarities of the functioning of the settlement. This settlement existed for a short time — from the end of the 10th century to the second half of the 12th century. The heyday of the settlement fell on the second half of the 11th — the fi rst half of the 12th century. During the excavations, 40 iron buckles, plaques on the belt and hooks were found. The peculiarity of these artifacts was that they were made according to samples that came to the Bulgars from Southern Siberia. Their prototypes were items of the Askiz archaeological culture. Such fi nds are typical for the Bulgar archaeological sites of the pre-Mongol period. In addition, Bulgar copies of Askiz originals spread beyond the borders of Volga Bulgaria. They are found among the medieval Mari, Udmurts, Permians, Mordovians. Th erefore, finding out the time of existence of such items is very important for dating the archaeological materials of the entire Volga-Kama region. Well-dated layers of the Ostolopovsky settlement allow this to be done. The analysis of the finds showed that they begin to occur in the third stratigraphic layer, which dates back to no earlier than the middle — second half of the 11th century. It contained a few items from a belt with an iron buckle and plaques on the belt that adorned it. Most of the finds come from the second layer, which was formed from the turn of the 11th–12th centuries until the second third of the 12th century. They are notable for their improved form design, which also included decoration of the surface with ornaments and possibly silver inlay. Finds of this type are no longer found in the upper horizon of the second layer. Thus, the period of the use of the Bulgar derivatives of Askiz products in the Ostolopovo settlement is the second half of the 11th — the second third of the 12th century. According to stratigraphy, the greatest use of such artifacts was in the first half of the 12th century.
Imagery of the Kurteke Rock-Shelter (Estern Pamir)
Authors:   Institute of Archaeology and Ethnography SB RAS, L. Zotkina , N. Sayfulloev ,   A. Donish Institute of History, Archaeology and Ethnography at the National Academy of Sciences of Tajikistan
Published: December 2022

The Kurteke rock-shelter images in the Eastern Pamirs were discovered in 1958. Later, in 1960, V.A. Ranov studied the paintings as well as the archaeological layers. After a signifi cant break, the fieldwork at the site was resumed in 2018 and 2019. Integrated interdisciplinary research led by S.V. Shnaider clarifi es the chronology of the stratifi ed Kurteke site, the paleoenvironmental features of the region and provides new data on the time of human occupation of the Eastern Pamir. Earlier, as part of general studies on this site, we published new fi ndings on the rock paintings presented on the two walls of the rock-shelter. This article focuses on generalization of currently available data on Kurteke murals. V.A. Ranov noted that the state of preservation of the images is extremely poor: most of them are not identifi able and look like blurring red mineral pigment. DStretch color filtering treatment allowed us to clarify some contours and details of the images, necessary for further interpretation. It is worth noting that some of the pigment spots visible without processing acquired clearer contours. The other part of spots neither in the field, nor on the photos without color filtration was not even recorded. Moreover, after treatment it is difficult to correlate the majority of paintings with concrete imagery and to find parallels to them.
Main Results of Archaeological Work in the Surkhandarya River Basin in Uzbekistan
Authors:   Northwestern University, Yu. Tan , A. Berdimuradov ,   Institute of Archaeology, Uzbekistan Academy of Sciences, M. Khasanov ,   Institute of Archaeology, Uzbekistan Academy of Sciences, Ji. Wang ,   Northwestern University
Published: December 2022

Archaeological excavations in the Surkhandarya River Basin show that the nomadic graves of the Rabat necropolis located in the foothill hilly areas of Northern Bactria belong to the second half of the 1st c. BCE — the fi rst half of the 2nd c. CE. This is probably a site of the great Yuezhi. Above-ground burials in naus-type crypts dating from the same period were found on the ruins of the settlement, near the flat part of the Surkhandarya valley, most likely belong to the Yuezhi before the formation of the Kushan Empire. The two types of graves, differing in their form and burial rite, location area, etc., only confirm the fact that the Great Yuezhi and Kushans of the Imperial era are not exactly the same ethnic groups. The discovery of Serkharakat, Chinartep and other necropolises in the upper reaches of the Surkhandarya River confirmed our assumptions about the patterns of distribution of ancient monuments and additionally reveals the diversity of cultural groups of the period from the pre-imperial Yuezhi to the Kushan Empire.
Medieval Mongolian Burials, Investigated in the Egiin-Gol Valley (Northern Mongolia)
Authors:   Altai State University, A. Tishkin , T.-O. Iderkhangai ,   Ulaanbaatar State University, D. Tsend ,   Ulaanbaatar State University,   Altai State University, S. Orgilbayar ,   Ulaanbaatar State University, B. Amgalanbat ,   National center for cultural heritage Mongolia, P. Erdenepurev ,   Ulaanbaatar State University,   Altai State University, B. Bamchimeg ,   Ulaanbaatar State University
Published: December 2022

In the summer of 2018, as part of a joint Mongolian-Russian expedition organised by staff from Ulaanbaatar and Altai Universities, archaeological research was carried out in the Egyin-gol valley (Hutag-Undur somon of the Bulgan aimag of Mongolia). The planned work included the excavation of four burials from Mongolian times in the localities of Ikh Khutul and Elst Khutul. This article presents the results of such activities in detail. Particular attention is paid to the recorded gravestones and grave structures, as well as the position and orientation of buried people. These data reflect the specifics of the implemented ritual in comparative analysis with the materials of other medieval graves discovered and excavated in the valley of Egijn Gol. There is a good prospect of studying and generalising information about archaeological sites from Mongolian times in an area which was planned to be flooded by a reservoir during the construction of a hydroelectric power station.
Wymagania dotyczące zawartości substancji szkodliwych w wyrobach rynkowych z tworzyw sztucznych i gumy. Cz. I. Opakowania, w tym materiały i wyroby z tworzyw sztucznych przeznaczone do kontaktu z żywnością
Authors: Kolasa Dorota , Samsonowska Katarzyna , Kaszuba Alicja , Stępkowska Aneta , Wróbel Justyna , Wróbel Kamil , Lach Jakub
Published: December 2022

Dokonano przeglądu aktualnych aktów prawnych nt. bezpieczeństwa produktów wprowadzanych na rynek Unii Europejskiej. Przegląd, dotyczący (w części I) przepisów w zakresie kontroli substancji szkodliwych w wyrobach opakowaniowych wykonanych (lub zawierających elementy) z tworzyw sztucznych, obejmuje zarówno akty prawne UE, jak i akty krajowe transponujące regulacje unijne do polskiego prawa w tym zakresie.
Ink based on poly(3,4-ethylene dioxythiophene), poly(sulfonostyrene) and silver nanoparticles (PEDOT/PSS/SNP) blends for fabrics printing
Authors: Shahrim Nur'Aishah Ahmad , Hafiz Nur Nadia Mohd , Ahmad Zuraida , Buys Yose Fachmi , Sarifuddin Norshahida
Published: December 2022

The influence of co-solvents such as: dimethylsulfoxide (DMSO), isopropyl alcohol (IPA), ethylene glycol (EG), ethanol (EtOH) and deionized water (DI) on the properties of ink based on poly(3,4-ethylene dioxythiophene), poly(sulfonostyrene) and silver nanoparticles (PEDOT/PSS/SNP) blends was investigated. The ink was obtained by the ultrasonic dispersion method by mixing PEDOT, PSS and SNP and then adding co-solvents. The ink was applied to the cotton fabric by printing method. The structure, electrical and functional properties of fabrics were investigated. The increase in electrical conductivity was found as a result of the phase separation between PEDOT and PSS due to the use of co-solvents. SEM micrographs showed good adhesion of the ink to the cotton fiber, which was confirmed by the FTIR method. The developed ink has great application potential, especially in electronic devices for biomedical purposes.
The kinetic degradation of LDPE films subjected to aggressive environments
Authors: Kashi Imad , Zeghouan Ouahida , Moussaceb Karim
Published: December 2022

The effect of natural and thermo-oxidative aging on the structure and physicochemical properties of LDPE films stabilized with hindered amine light stabilizers (HALS) was investigated. Based on multiple linear regression analysis (MLRA) mathematical models to predict the lifetime of the LDPE were developed. Four statistical criteria were used to evaluate the developed models: residual variance, coefficient of determination, Student's test and the Fisher-Snedecor test. The half-life times predicted by the mathematical models were found to be statistically significant (p < 0.05).
Aqueous emulsions from oxidized polyethylene waxes stabilized with non-ionic agents
Authors: Krysztofik Łukasz , Osowiecka Blandyna , Liszyńska Barbara , Zieliński Janusz , Zakarzecki Marcin
Published: December 2022

The stable emulsions from oxidized polyethylene waxes with the use of various non-ionic emulsifiers from the group of fatty alcohol ethoxylates with HLB in the range 11−16 were obtained. The effectiveness of the emulsification was assessed by measuring the dispersed phase particle size and the emulsion stability. The highest emulsifying efficiency was achieved using a non-ionic emulsifier with HLB of 16.3.
The Use of Visual Learning Media in The Development Optimization of Children with Mild Mental Retardation
Authors: Puspitaloka Viny Anggradini , Putro Khamim Zarkasih , Rukmana Tri , Elvia Fifi
Published: December 2022

Children with mild mental retardation are different from normal children in general. Mild mentally retarded children have learning difficulties evident in the academic field. Therefore, to teach learning materials to children with mild mental retardation, teachers need to provide learning media. One of them is visual media. So this study aims to analyze the use of visual learning media in optimizing all aspects of the development of mild mentally retarded children. This research uses the literature review method with thematic structure data collection techniques and Critical appraisal analysis techniques. In this study, all results obtained in the reviewed literature showed that visual learning media significantly influenced the development of children with mild mental retardation. The visual learning media used in the research that has been carried out are blocks, counting boards, drawing cards, word walls, busy books, and picture crosswords. This is undoubtedly very helpful for teachers in the learning process because visual media can contain various learning materials to increase the interest and enthusiasm for learning of children with mild mental retardation.
The Role of the Teacher In Managing Child Emotions At American Academy Casablanca School Morocco
Authors: Kamil Nurhusni , Sultan Haseena
Published: December 2022

Emotions are the most basic thing in a person. Emotional management needs to be done early on, especially for anyone so that emotions can be controlled in a better direction. In early childhood emotions need to be managed even when starting to enter school age. Many impacts will occur if a child is not able to manage his emotions properly. Emotions generated by children can be caused by many factors such as external and internal factors. The method used in this research is qualitative with a case study approach. In this study the teacher who will be the object of this research is 1 teacher. The criteria are teachers who teach early childhood aged 4-5 years who are included in group B. The purpose of this research is to see the teacher's role in managing children's emotions at the American Academy Casablanca in Morocco. Data collection techniques using interviews and questionnaires. The results of the study show that there is a teacher's role in managing children's emotions during play activities in learning activities in the classroom. There are several ways and methods that are applied by the teacher so that children are able to control their emotions in a better direction, such as the teacher will give advice to children when children are angry or sad. The next step is the teacher will use the ttime-out method if the first step cannot make the child control his emotions with the teacher's expectations.
ICO and IPO Markets: An Overview and Prospects
Authors:   The Department of World Finance, Faculty of International Economic Relations, Finance University under the Government of the Russian Federation, Abrekov Magomed , Vlasov Andrey ,   National Research University Higher School of Economics (HSE University),   The Center for Institutional Evolutionary Economics and Applied Problems of Reproduction, Institute of Economics of the Russian Academy of Sciences (IE RAS)
Published: December 2022

The purpose of this work is to study the investment capital markets by analysing the IPO and ICO procedures, identifying the main trends, leading sectors and comparing their volumes. The methodological basis was a retrospective analysis of the development of various forms of investment attraction (IPO and ICO). The main research methods were deduction, induction, synthesis and logical analysis. This article examined the main trends taking place in the IPO and ICO markets; key types of used blockchain platforms were identified; the leading countries and sectors in terms of the amount of funds raised are presented. The ICO market showed high growth rates in 2013–2018, but did not reach volumes comparable to the IPO market. Most of the projects that used the ICO (digital token issuance) procedures chose the Ethereum blockchain system as a platform, implemented projects in the fintech and IT industries, infrastructure development and decentralized applications (DApps). The leading states, residents, which have carried out the largest number of ICO procedures, are the USA, Singapore, United Kingdom and Hong Kong. In the IPO market, the largest volume of funds was attracted by projects from such sectors as finance, consumer services, oil and gas, industry and healthcare. The US remains the main platform chosen by companies for IPOs. The US is followed by the UK, China and Hong Kong
Convergence of Income Inequality in Russia’s Regions
Authors:   Russian Academy of National Economy and Public Administration (RANEPA), Polbin Andrey ,   Deputy Head of the International Laboratory for Mathematical Modeling of Economic Processes Gaidar Institute for Economic Policy, Ivakhnenko Tatiana ,   Russian Academy of National Economy and Public Administration (RANEPA)
Published: December 2022

In this paper we test convergence of income inequality in Russia’s regions for the period 1995–2020. To do this, conditional and unconditional beta convergence models for the regional Gini index are evaluated on cross-sectional and panel data using time and spatial effects. Estimates of the models show that both conditional and unconditional convergence of income inequality takes place in Russia’s regions. It is shown that the rate of convergence varies significantly within the considered period: the levels of income inequality in the regions converged most strongly at the beginning of the period with a gradual slowdown in the rate of convergence in subsequent periods. This result may be related to the recovery growth and redistribution policy in the 2000s, as well as the consequences of the 2014 crisis. The use of the same initial characteristics, such as GRP per capita, level of education and population, accelerates convergence. Spatial effects are statistically significant for models of unconditional, but not conditional convergence, but do not affect the estimates obtained. When considering a panel data structure with the inclusion of fixed time effects, convergence estimates increase for both unconditional and conditional convergence
Vietnam and Russia: Mutual Economic Cooperation in Changing Geopolitical and Geo-Economic Conditions
Authors:   Institute of Economics of the RAS, Vardomskiy Leonid
Published: December 2022

The issues of mutual economic relations between Vietnam and Russia (SRV) in the context of global transformations are studied. In Soviet times, it was based on technical and financial assistance to the USSR, which was determined by ideological proximity and geopolitical interests. Market transit and the orientation of the new Russia to the West sharply reduced the volume of economic interaction. In the 2000s, during the recovery growth and the transition to a multi-vector foreign policy, mutual trade relations began to grow, but they were much slower in terms of trade with regional partners. In the last decade, the role of geopolitics has increased again, and, above all, the peculiarities of relations between both countries with China and the United States. Over the years of cooperation between the SRV and the Russian Federation, an extensive system of relations at the political level has been built. But this does not create a sufficient incentive for the development of economic relations. At the level of business structures directly involved in their construction, the influence of global geopolitical processes and geo-economic conditions is felt more strongly. The situation for mutual economic ties has deteriorated greatly in the face of harsh Western sanctions. The study showed that geo-economic conditions of cooperation can be improved by developing institutions that mutually promote commercial proposals to each other’s markets and create business models for their implementation
Intervención Conductual Online para el Control Glucémico en Diabetes Mellitus Tipo 2: Estudio de caso.
Authors: Ramirez Perez Jonathan Israel , Reynoso Erazo Leonardo
Published: December 2022

El objetivo del presente estudio fue evaluar la eficacia de un programa de intervención conductual en las Conductas de Adherencia al Tratamiento No Farmacológico (CATNF) y el control glucémico en un paciente con DMT2. Se describe un estudio de caso. Masculino de 65 años que reporta dificultades para modificar hábitos alimentarios y descontrol de su enfermedad, reportando glicemias postprandiales entre 200 y 300 mg/dl. Se aplicó una intervención conductual de 11 sesiones dividida en tres fases: evaluación, tratamiento y seguimiento. Se realizaron mediciones diarias de glicemia capilar en ayunas y postprandial nocturna y un reporte semanal de consumo de alimentos. Se efectuaron análisis visuales y se calculó el tamaño del efecto para las mediciones entre fases. La intervención promovió una disminución en los niveles de glicemia en ayunas y postprandial, con tamaños del efecto medio. Además, hubo una disminución en la frecuencia del consumo de alimentos chatarra y aumentó el consumo de frutas y verduras. Dichos cambios se mantienen a dos meses de seguimiento.  Los resultados muestran la eficacia de la intervención para aumentar las CATNF y promover la disminución de niveles de glucosa.  La eficacia se atribuye a la información proporcionada en la psicoeducación, que generó patrones de pensamiento con relación a las consecuencias del comportamiento, así como la sensibilidad y vulnerabilidad percibida. Además, las técnicas de autocontrol contribuyeron a la producción de la intención y la motivación para ejecutar y mantener los comportamientos objetivo.
Educación emocional en el balonmano Morvedre.
Authors: Corrales Camuñas Ana , García Lluch José Joaquín , Sales Rubio Pascual José
Published: December 2022

El artículo describe una experiencia en educación emocional en deporte, en concreto con once jugadoras de un equipo infantil femenino de balonmano. El principal objetivo, es integrar la educación emocional a lo largo de toda la competición, con una tarea semanal para cada partido o jornada, que se realiza individualmente a través de unos cuadernillos emocionales elaborados para la intervención y que sirven de base para realizar dinámicas grupales breves. Los cuestionarios TMMS-24 y EAF, sirvieron de pre y post evaluación de la intervención, cuyos resultados muestran cambios significativos en variables como la actitud hacia el juego duro y la victoria, así como en atención emocional. Se concluye que, un buen trabajo psicológico continuo a lo largo de la temporada, poniendo el acento y fijándose en un mejor aprovechamiento del tiempo de las jugadoras en las instalaciones y una involucración de padres y técnicos en la misma actividad, puede ayudar a los/las jóvenes deportistas a mejorar ciertas habilidades emocionales y, por lo tanto, su rendimiento y bienestar en pista.
Explorando nuevas formas de enseñar los fundamentos técnicos de la marcha atlética
Authors: González Fernández Mª Dolores , Vives-Ribó Joan
Published: December 2022

Este trabajo describe una experiencia profesional consistente en la aplicación de las indicaciones comunicativas del modelo ‘Cadena de la Conciencia’ (Vives, 2011), por parte de las entrenadoras de un club de atletismo, en la modalidad de marcha atlética. Esta disciplina tiene un claro componente técnico, y la ejecución incorrecta puede conllevar descalificación por parte del jurado de la competición. De ahí la importancia de optimizar los aprendizajes iniciales para conseguir los automatismos adecuados. Para ello, se adaptaron las consignas del modelo en los entrenamientos específicos dedicados a la técnica. Los cambios más relevantes consistieron en la explicitación de los objetivos, el uso de palabras clave para concentrar, la limitación de las correcciones al objetivo planteado, y el uso del diálogo en la evaluación final para generar conciencia sobre los aprendizajes. Se concluye que el modelo es aplicable para la enseñanza de la marcha atlética, y se plantean estudios futuros para valorar los efectos sobre el aprendizaje y sobre la motivación y la confianza de los atletas.