bluuebunny/crossref_metadata_2025 huggingface dataset:
Utility of Alternative Promoters for Foreign Gene Expression Using the Baculovirus Expression Vector System
Authors: Bruder Mark R. , Aucoin Marc G.
Published: November 2022

The baculovirus expression vector system (BEVS) is a widely used platform for recombinant protein production for use in a wide variety of applications. Of particular interest is production of virus-like particles (VLPs), which consist of multiple viral proteins that self-assemble in strict stoichiometric ratios to mimic the structure of a virus but lacks its genetic material, while a significant amount of effort has been spent on optimizing expression ratios by co-infecting cells with multiple recombinant BEVs and modulating different process parameters, co-expressing multiple foreign genes from a single rBEV may offer more promise. However, there is currently a lack of promoters available with which to optimize co-expression of each foreign gene. To address this, previously published transcriptome data was used to identify promoters that have incrementally lower expression profiles and compared by expressing model cytoplasmic and secreted proteins. Bioinformatics was also used to identify sequence determinants that may be important for late gene transcription regulation, and translation initiation. The identified promoters and bioinformatics analyses may be useful for optimizing expression of foreign genes in the BEVS.
Changes in the Cervical Microbiota of Women with Different High-Risk Human Papillomavirus Loads
Authors: Camargo Milena , Vega Laura , Muñoz Marina , Sánchez Ricardo , Patarroyo Manuel Elkin , Ramírez Juan David , Patarroyo Manuel Alfonso
Published: November 2022

The cervical microbiota is essential in female sexual health, and its altered states seem to have a central role in the dynamic of high-risk papillomavirus (hrHPV) infections. This study aimed to evaluate the variation in bacterial communities’ compositions according to hrHPV. We collected two samples per woman, with a difference of 12 ± 1 months between them, and performed a follow-up on 66 of these women. The viral load (VL) of the hrHPV was estimated by quantitative PCR (qPCR), then it was normalized (using the HMBS gene as reference) and transformed to the Log10 scale to facilitate the interpretation. The VL was categorized as Negative, without hrHPV copies; Low, less than 100 hrHPV copies; Medium, between 100 to 102 hrHPV copies; and High, >102 hrHPV copies. The microbiota composition was described through the Illumina Novaseq PE250 platform. The diversity analyses revealed changes regarding the hrHPV VL, where women with low VL (<100 hrHPV copies) presented high diversity. The community state type (CST) IV was the most common. However, in women with high VL, a lower association with Lactobacillus depletion was found. Lactobacillus gallinarum and L. iners were the most abundant species in women with high VL, whereas women with low VL had a 6.06 greater probability of exhibiting Lactobacillus dominance. We identified conspicuous differences in the abundance of 78 bacterial genera between women with low and high VL, where 26 were depleted (e.g., Gardnerella) and 52 increased (e.g., Mycoplasma). A multilevel mixed-effects linear regression showed changes in the diversity due to the interaction between the measurement time and the VL, with a decrease in diversity in the second follow-up in women with low VL (Coeff. = 0.47), whereas the women with medium VL displayed an increase in diversity (Coeff. = 0.58). Here, we report for the first time that the cervical microbiota is influenced by the number of copies of hrHPV, where a decrease in the abundance of Lactobacillus, greater diversity, and enrichment of bacterial taxa is relevant in women with low VL.
Wastewater-Based Epidemiology Mitigates COVID-19 Outbreaks at a Food Processing Facility near the Mexico-U.S. Border—November 2020–March 2022
Authors: Innes Gabriel K. , Schmitz Bradley W. , Brierley Paul E. , Guzman Juan , Prasek Sarah M. , Ruedas Martha , Sanchez Ana , Bhattacharjee Subhadeep , Slinski Stephanie
Published: November 2022

Background: Wastewater-based epidemiology (WBE) has the potential to inform activities to contain infectious disease outbreaks in both the public and private sectors. Although WBE for SARS-CoV-2 has shown promise over short time intervals, no other groups have evaluated how a public-private partnership could influence disease spread through public health action over time. The aim of this study was to characterize and assess the application of WBE to inform public health response and contain COVID-19 infections in a food processing facility. Methods: Over the period November 2020–March 2022, wastewater in an Arizona food processing facility was monitored for the presence of SARS-CoV-2 using Real-Time Quantitative PCR. Upon positive detection, partners discussed public health intervention strategies, including infection control reinforcement, antigen testing, and vaccination. Results: SARS-CoV-2 RNA was detected on 18 of 205 days in which wastewater was sampled and analyzed (8.8%): seven during Wild-type predominance and 11 during Omicron-variant predominance. All detections triggered the reinforcement of infection control guidelines. In five of the 18 events, active antigen testing identified asymptomatic workers. Conclusions: These steps heightened awareness to refine infection control protocols and averted possible transmission events during periods where detection occurred. This public-private partnership has potentially decreased human illness and economic loss during the COVID-19 pandemic.
What’s Next for Flu? Out-of-Season Circulation of Influenza Viruses in Southern Italy, August 2022
Authors: Loconsole Daniela , Centrone Francesca , Aprile Valerio , Sallustio Anna , Casulli Daniele , Accogli Marisa , Sacco Davide , Zagaria Riccardo , Chironna Maria
Published: November 2022

The COVID-19 pandemic has modified the seasonal pattern of respiratory infections. The objective of the present study is to characterize the out-of-season circulation of influenza viruses and an influenza outbreak that occurred in southern Italy in August 2022. Nasopharyngeal swabs collected from patients with influenza-like illnesses (ILI) were tested for the presence of influenza and other respiratory viruses. Epidemiological investigations on 85 patients involved in an influenza outbreak were performed. Sequencing and phylogenetic analysis of hemagglutinin genes was undertaken on samples positive for influenza A. In August 2022, in the Apulia region (Italy), influenza A infection was diagnosed in 19 patients, 18 infected with A/H3N2 and one with A/H1N1pdm09 virus. Seven influenza-positive patients were hospitalized with ILI. A further 17 symptomatic subjects, associated with an influenza outbreak, were also tested; 11 were positive for influenza A/H3N2 virus. Phylogenetic analysis of 12 of the A/H3N2 sequences showed that they all belonged to subclade 3C.2a1b.2a.2. The A/H1N1pdm09 strain belonged to subclade 6B.1A.5a.2. The out-of-season circulation of the influenza virus during the summer months could be linked to changing dynamics in the post-COVID-19 era, as well as to the impact of climate change. Year-round surveillance of respiratory viruses is needed to monitor this phenomenon and to provide effective prevention strategies.
Specific Binding and Endocytosis of Liposomes to HEK293T Cells via Myrisoylated Pre-S1 Peptide Bound to Sodium Taurocholate Cotransporting Polypeptide
Authors: Hinuma Shuji , Fujita Kazuyo , Kuroda Shun’ichi
Published: November 2022

(1) Background: Sodium taurocholate cotransporting polypeptide (NTCP) functions as a key receptor for the hepatitis B virus (HBV) infection. Analyzing HBV and NTCP interaction is an important issue not only for basic research but also for the development of anti-HBV therapeutics. We developed here a novel model system to analyze the interaction of NTCP with liposomes instead of HBV. (2) Methods: Liposomal binding and endocytosis through NTCP in HEK293T cells were achieved by serial treatments of HEL293T cells transiently expressing NTCP-green fluorescence protein (GFP) fusion protein with a synthetic biotinylated pre-S1 peptide (Myr47-Bio) and streptavidin (SA) complex (i.e., Myr47-Bio+SA) followed by biotinylated liposomes. By this procedure, binding of [biotinylated liposomes]-[Myr47-Bio+SA]-[NTCP-GFP] was formed. (3) Results: Using this model system, we found that liposomal binding to NTCP on the cell surface via Myr47-Bio+SA was far more efficient than that to scavenger receptor class B type 1 (SR-B1). Furthermore, liposomes bound to cell surface NTCP via Myr47-Bio+SA were endocytosed into cells after cells were cultured at 37 °C. However, this endocytosis was suppressed by 4 °C or cytochalasin B treatment. (4) Conclusions: This model system will be useful for not only analyzing HBV entry mechanisms but also screening substances to prevent HBV infection.
Experimental Investigation of Mechanisms of Droplet Entrainment in Annular Gas-Liquid Flows: A Review
Authors: Cherdantsev Andrey V.
Published: November 2022

Entrainment of liquid from the film surface by high-velocity gas stream strongly affects mass, momentum and heat transfer in annular flow. The construction of basic assumptions for simplified physical models of the flow, as well as validation of numerical models, requires detailed experimental investigation of droplet entrainment process and the preceding stages of film surface evolution. The present paper analyzes the achievements and perspectives of application of various experimental approaches to qualitative and quantitative characterization of droplet entrainment. Optical visualization in at least two planes simultaneously may provide enough information on transitional liquid structures and detaching droplets, given that the side-view image is not obscured by the wall film. A planar LIF technique is not suitable for this purpose, since real objects are hidden by curved agitated interface and replaced by optical artifacts. To characterize the waves evolving into the transitional liquid structures, film thickness measurements in the plane of the wall are necessary. Such measurements can be achieved by intensity-based optical techniques, such as Brightness-Based LIF, near-infrared or X-ray attenuation techniques, combined with the side-view observations.
An Automated Machine Learning Engine with Inverse Analysis for Seismic Design of Dams
Authors: Hariri-Ardebili Mohammad Amin , Pourkamali-Anaraki Farhad
Published: November 2022

This paper proposes a systematic approach for the seismic design of 2D concrete dams. As opposed to the traditional design method which does not optimize the dam cross-section, the proposed design engine offers the optimal one based on the predefined constraints. A large database of about 24,000 simulations is generated based on transient simulation of the dam-foundation-water system. The database includes over 150 various dam shapes, water levels, and material properties, as well as 160 different ground motion records. Automated machine learning (AutoML) is used to generate a surrogate model of dam response as a function of thirty variables. The accuracy of single- and multi-output surrogate models are compared, and the efficiency of the design engine for various settings is discussed. Next, a simple yet robust inverse analysis method is coupled with a multi-output surrogate model to design a hypothetical dam in the United States. Having the seismic hazard scenario, geological survey data, and also the concrete mix, the dam shape is estimated and compared to direct finite element simulation. The results show promising accuracy from the AutoML regression. Furthermore, the design shape from the inverse analysis is in good agreement with the design objectives and also the finite element simulations.
Anti-Clogging Performance Optimization for Shunt-Hedging Drip Irrigation Emitters Based on Water–Sand Motion Characteristics
Authors: Qin Cheng , Zhang Jinzhu , Wang Zhenhua , Lyu Desheng , Liu Ningning , Xing Shaobo , Wang Fei
Published: November 2022

To improve the irrigation quality and anti-clogging performance of the emitter, it is necessary to design and optimize its flow channel structure. The shunt-hedging drip irrigation emitter (SHDIE) flow channel is a new type of flow channel. Using computational fluid dynamics, by setting different conditions (such as particle size and injection position), the motion trajectory of sand particles and flow field distribution characteristics of the shunt-hedging flow channel were simulated. According to the simulation results, a new anti-clogging structural optimization scheme was proposed, and physical experiments verified its feasibility. The results showed that the flow index of the original flow channel (SHDIE1) and optimized flow channel (SHDIE2) were 0.479 and 0.486, respectively, which mainly relied on the shunting and hedging of water flow to energy dissipation. For sand particles with diameters of 0.05, 0.10, and 0.15 mm, the average values of the velocity amplitude ratio, η, were 0.9998, 0.9994, and 0.9991, respectively; the average values of the velocity phase difference, β, were −0.143°, −0.320°, and −0.409°, respectively. A larger sand particle diameter led to worse followability and a higher risk of blocking the channel. When the sand particles collided with the sensitive region of the flow channel, their movement direction would suddenly change, entering the vortex area. After colliding with the sensitive region of edge A, the maximum probability of sand particles entering the vortex area was increased to 87.5%, and then they stayed in the vortex area under the effect of the sensitive regions of edges B and C. After the sensitive regions were removed, the motion trajectories of sand particles became regular and smooth. The optimized flow channel’s (SHDIE2) anti-clogging performance was greatly improved by 60%, with a 1.46% loss of hydraulic performance. This study can provide theoretical support for designing the high anti-clogging emitter.
Big Data as the subject of a transaction in civil turnover under the law of the Russian Federation
Authors: Kravchenko Artur G. , Ovchinnikov Aleksey I. , Rabets Anna P. , Chekulaev Sergey S.
Published: November 2022

The article aims to investigate the issues concerning the definition of the big data concept, as well as the problem of civil turnover of big data in the legislation of the Russian Federation. Approaches to this definition enshrined in doctrinal legal acts and investigated in the legal literature are analyzed. The features and peculiarities of big data are considered. The conclusion about the need to legislate the basic categories in the field of big data to clarify the place of this object in the system of objects of civil rights is made. The study has also analyzed the risks of including big data in civil law turnover. Given the results, substantially practical approaches to regulating civilized forms of big data circulation should be the established mechanisms of civil liability for the use of big data that have resulted in derogation or limitation of the rights of citizens.
Kajian Hukum terhadap Pelaku Tindak Pidana Kecelakaan Lalu Lintas yang Dilakukan Anak di Bawah Umur dalam Perspektif Kriminologi Studi pada Satlantas Polres Pelabuhan Belawan
Authors: Rachwi Ritonga Muhammad , Ediwarman Ediwarman , Sutiarnoto Sutiarnoto
Published: November 2022

Modernization is not only in the field of electronics, but also in the field of transportation. As a result of this modernization, many young people, especially children, are affected. The role of parents to monitor the growth and development of a child is very much expected in living life in the era of modernization. In the case file Number: BP/01/I/2017/Traffic. Police Report Number: LP/0204/244/XII/2016/LL contains a case of a traffic accident crime committed by a minor that caused the death of a pedestrian. Based on research and file analysis, the diversion step is a step taken by the Belawan Harbor Police Traffic Unit in resolving the traffic accident case committed by minors and is guided by Law No. 11 of 2012 and Supreme Court Regulation No. 4 of 2014 about diversion and procedures for its implementation. Factors that cause traffic accidents committed by minors in the jurisdiction of the Belawan Harbor Police Traffic Unit, namely; parental permission, a child's habits, long distance travelled, the child's living environment and the child's social environment. The prevention efforts of the Belawan Harbor Police Traffic Unit in preventing accidents carried out by minors were hindered by the COVID-19 pandemic. However, the efforts of the Belawan Harbor Police Satlantas in handling the case file Number: BP/01/I/2017/Traffic. Police Report Number: LP/0204/244/XII/2016/LL should be appreciated and imitated by other police, because it prioritizes preventive action by taking a policy of diversion.
Kajian Hukum Terhadap Anak Yang Melakukan Tindak Pidana Narkotika Dalam Perspektif Kriminologi Studi di Polresta Deli Serdang
Authors: Akbar Simatupang Rajarif Syah , Siagian Abdul Hakim , Zulyadi Rizkan
Published: November 2022

This study aims to find out the causal factors, modus operandi and prevention efforts of children who commit narcotics crimes in the perspective of criminology in Deli Serdang Police.. This research uses normative legal methods by using a normative juridical approach (Legal Reseach) to obtain secondary data conducted by research and interview, to obtain primary data through library materials and invitees. The results showed that the legal study of children who commit narcotics crimes in the perspective of criminology, based on indicators are as follows: First, the causative factors of narcotics crimes committed by children are internal factors (factors obtained by children from the family and from within the child themselves and external factors (factors obtained from the environment, association, economic situation and cultural influences abroad). Second, the modus operandi carried out by children in committing narcotics crimes is carried out in groups and individuals, the child can use narcotics by lying to parents in terms of material (pocket money) to commit criminal acts of theft. Third, the efforts and prevention so that narcotics crimes committed by children are not repeated through the existence of legal policies consisting of repressive and preventive efforts by the Deli Serdang Police.
Implementasi Peraturan Menteri Dalam Negeri No 41 tahun 2012 tentang Pedoman Penataan Pemberdayaan Pedagang Kaki Lima di kelurahan Suka Maju Kecamatan Medan Johor
Authors: Aziz Ahmad Robiul , Zainuddin Zainuddin , Hartono Budi
Published: November 2022

The arrangement of street vendors is felt to be very important to create an orderly and comfortable atmosphere for the people of Medan Johor village. The chaotic and disorganized situation that occurred around the Medan Johor sub-district was caused by street vendors who were not well organized. To find out the implementation of the Minister of Home Affairs Regulation No. 41 of 2012 concerning Guidelines for the Empowerment of Street Vendors in Suka Maju Village, Medan Johor Subdistrict, this research was conducted. The focus of the research is on implementing the policy of the Minister of Home Affairs Regulation. Structuring the empowerment of street vendors requires evaluation and relocation. The purpose of this study is to determine the extent to which Ministerial Regulation No. 41 of 2012 is applied to the Suka Maju sub-district, Medan Johor sub-district. Data was collected through observational studies, interviews and documentation studies. Further analysis is carried out. The methodology in this research is descriptive qualitative. The results of the study show that there is a need for more optimal socialization. This study concludes that the relocation of street vendors in Suka Maju sub-district, Medan Johor sub-district has not run optimally and that many traders still do not want to be relocated to places that have been provided by the Suka Maju sub-district, Medan Johor sub-district.
Analisis Kinerja Rencana Pembangunan Jangka Menengah Daerah (RPJMD) Kabupaten Padang Lawas Utara Tahun 2019-2023
Authors: Siregar Minta Ito , Adam Adam , Isnaini Isnaini
Published: November 2022

This study aims to analyze the form of evaluating the performance of the North Padang Lawas Regency Regional Medium-Term Development Plan (RPJMD) for 2019-2023 and analyze the inhibiting factors for the 2019-2023 Regional Medium-Term Development Plan (RPJMD) Performance Evaluation of North Padang Lawas Regency. The form of research used in this research is descriptive research with observation data collection techniques, documentation studies and interviews. While the data analysis used is descriptive analysis. The results of this study indicate that the evaluation of the Performance of the Regional Medium-Term Development Plan (RPJMD) of North Padang Lawas Regency for 2019-2023 shows that there are contradictory facts with the maximum efforts that have been made by the North Padang Lawas Regency Bapelitbang in the preparation and control but have not shown maximum results, especially on KPI improvement. Although the term of the RPJMD has not yet expired, every year there are evaluation aspects that can be seen. In other words, there are factors that hinder the implementation of the targets that must be achieved in the North Padang Lawas Regency RPJMD for 2019-2023. Furthermore, there are seven obstacles to the Regional Medium-Term Development Plan (RPJMD) of North Padang Lawas Regency for 2019-2023. These seven obstacles are basically what makes the targets set every year have not been implemented, such as the target in 2019 where North Padang Lawas seeks to implement the concept of building and 2020 with the concept of serving invisible. This can be seen from the KPI, especially the aspects of poverty and stagnant investment development. Then From the six aspects of performance evaluation that Dunn put forward, each aspect still has problems that need to be studied further. This is homework for Bapelitbang North Padang Lawas Regency in meeting the targets and targets of the RPJMD at least until the end of the period in 2023. Suggestions from this research are: the need for regulation socialization and collaboration with every stakeholder interested in strategic design, and it needs to be integrated where Bapelitbang who become the executor of the task need to improve their ability in supervision and control.
Perlindungan Hukum terhadap Pemegang Hak Merek Minyak Biawak yang Ditiru
Authors: Pakpahan Emir Syarif Fatahillah , Nababan Febyola , Dianawati Lili
Published: November 2022

The purpose of this study was to find out the legal provisions or regulations regarding trademark rights according to the trademark law, violations and legal protection of registered trademarks and legal protection against holders of the rights to the copy of the Biawak oil mark. The research is focused on the legal protection of the rights holders of the lizard oil brand. In order to approach this problem, a reference to the theory of legal protection and the theory of legal certainty is used. Data was collected through document analysis, interviews and observations using a qualitative approach. Based on the findings in the field that the Legal Provisions or Regulations Regarding Mark Rights according to the Trademark Law are regulated in the Trademark Law and Geographical Indications. Violation and Legal Protection of registered Marks, may be subject to criminal, civil, and administrative law sanctions. Legal Protection for Copyright Holders of Imitated Biawak Oil. In this case, it demands compensation and the cessation of all use of the mark. The Commercial Court was sued (Article 76 paragraph 1 and paragraph 3 of the Trademark and Geographical Indication Law.
Hubungan Tingkat Kontrol Diri dengan Perilaku Konsumtif pada Remaja Penggemar Kpop di Komunitas ONCE Medan
Authors: Bogenvile Valen , Rosandi Tania , Siregar Doharma Indawaty , Siagian Ria Wulandari , Sinurat Yunika Maria , Dwi Putra Achmad Irvan
Published: November 2022

This study was intended to find out the relationship between self-control and Consumtive behavior in teenagers k-pop fans in the ONCE community Medan. The research subject used in this study were 100 teenagers k-pop fans in the ONCE community at medan using purposive sampling technique. This study used quantitative method, data collection used 40-item of self-control scale and 40-item of psychological consumtive behavior scale. The assumption test consisted of normality test and linearity test. The data were analyzed using Pearson Product Moment correlation test with the SPSS version 25.0 for Windows. The data analysis showed a negative correlation between between self-control and consumtive behavior in teenagers k-pop fans in the ONCE community Medan with pearson product moment coefficient of correlation r= -0,384 dan sig sebesar 0,000 (p <0,05). These results indicate that the research hypothesis is accepted. Meanwhile, the effective contribution of self-control in influencing consumptive behavior is 14.7 percent. From these results, it is concluded that the hypothesis, which stated that there is a negative relationship between selfcontrol and consumtive behavior is acceptable.
Analisis Fungsi Subbagian Humas Sekretariat Dewan dalam Meningkatkan Kinerja Dewan Perwakilan Rakyat Provinsi Aceh
Authors: Lestari Aula , Husna Cut Asmaul
Published: November 2022

The purpose of this study was to identify the function of public relations in the DPRA Secretariat in order to improve management performance. The extent to which the public relations sector of the DPRA secretariat has developed the existing public relations function into a more varied function with the aim of improving the relevant agencies is also studied in this study. The problem is focused on the performance of the public relations division of the Aceh Provincial DPRD. The method used in this study is a qualitative approach, where the procedures in the research produced are descriptive data, namely words or written answers from several sources and the results of direct observations in the field. Natural objects or natural settings are objects used in qualitative research which are often referred to as naturalistic research. Based on the results of the study, it can be concluded that the functions of the Public Relations, Protocol, and Publication Section of the Aceh DPR Secretariat have been carried out properly and in an orderly manner. The DPRA Public Relations Secretariat regulates its duties and functions slightly differently, but still in accordance with the applicable laws and regulations. This can be seen from the division of tasks and functions of public relations into several points, each of which has different and interconnected tasks and functions. Of course, public relations, protocols and publications have an impact on improving the performance of the Aceh DPR, but more specifically in this regard, consistency in fighting for people's aspirations and establishing relationships with the media in collaboration with the Aceh Provincial DPRD.
Pemikiran Politik Thomas Hobbes Dalam Serial Drama Squid Game
Authors: Elyta Elyta , Hertanto Hertanto
Published: November 2022

In 2021, South Korea will make the Squid Game drama series with the mystery horror genre. The research will look at the political thinking of Thomas Hobbes in this series with the aim of analyzing the form of natural consciousness, social contract in the form of the State which is broadcast through storylines, dialogues and descriptions of the situation in the Korean drama series Squid Game. This article is a literature study on the state of nature, social contract and the concept of the state from Thomas Hobbes' political thought through the drama series Squid Game produced from South Korea. His opinion of the state is scary, cruel, and obeyed like Leviathan to make the disorderly state of human nature controllable. Human nature is homo homini lupus or humans are wolves to each other. The social contract according to Thomas Hobbes is an agreement between the people and the state, but the state is not bound by the social contract. The state/king position is above the social contract, the state has absolute authority or is called the king, it cannot be wrong. This study concludes that in the Korean drama series Squad Game, there is a thought by Thomas Hobbes which states the importance of absolute state power to create perfection. Peace can be obtained by presenting fear to the individual through the State, conflict will be avoided, society will be subject to the law with fear that is continuously maintained by the State.
Analisis Kualitas Pelayanan Publik pada Dinas Perpustakaan dan Arsip Provinsi Sumatera Utara
Authors: Siahaan Riana , Isnaini Isnaini , Adam Adam
Published: November 2022

This study aims to analyze the quality and factors that influence public services at the Library and Archives Service of North Sumatra Province. The services available at the North Sumatra Provincial Library and Archives Service are public services, children's services, deposit services, reference services, digital services and mobile library services. The research method used is descriptive research with a qualitative approach. Data collection techniques used observation, study documentation and interviews. Data analysis used descriptive analysis. The results of this study indicate that the quality of public services at the Library and Archives Service of North Sumatra Province refers to Zeithaml's theory, namely from the dimensions: 1) Reliability (reliability); 2) Responsiveness (responsiveness); 3) Assurance (guarantee); 4) Empathy (empathy); 5) Tangibles (physical evidence). Everything has been done well, but the Tangibles dimensions (physical evidence) have not been maximized in the form of the problematic INSLISLITE application, the room temperature is not cold enough, the room lacks lighting. Factors that affect Public Service Services at the Library and Archives Service of North Sumatra Province are: 1) Inadequate facilities; 2) Budget that has not been maximized.
Pengaruh Kecerdasan Emosi dan Kepribadian Hardiness terhadap Resiliensi Belajar pada Masa Pandemi Pada Siswa MAN Asahan
Authors: Lutfiah Aisyah , Menanti Asih , Hasanuddin Hasanuddin
Published: November 2022

This study aims to determine the effect of emotional intelligence and personality hardiness on learning resilience. This research is a quantitative study, using a research sample of 95 people, taken in total from the research population. Sampling with total sampling technique. Data analysis used multiple regression analysis. The results showed that (1) There was a significant positive effect of emotional intelligence on learning resilience, seen from the value of the determinant coefficient (Rx1.y) = 0.633 with p = 0.000 < 0.050, meaning that there was a positive influence of emotional intelligence on learning resilience; (2) There is a significant positive effect of hardiness personality on learning resilience as seen from the value of the determinant coefficient (Rx2.y) = 0.413 with p = 0.000 < 0.050, meaning that there is a positive influence of hardiness personality on learning resilience; (3) there is a significant positive effect of emotional intelligence and personality hardiness on learning resilience seen from the value of the determinant coefficient (Rx1.x2.y) = 0.539 with p = 0.000 < 0.050, meaning that there is a positive relationship between emotional intelligence and personality hardiness on learning resilience. The percentage of contribution given by the influence of emotional intelligence and personality hardiness simultaneously on learning resilience is 29.1%.
Perbedaan Motivasi Belajar Dan Minat Belajar Antara Siswa Yang Belajar Daring Dan Luring Pada Pelajaran Bahasa Indonesia Di SMP Swasta Katolik Budi Murni 3 Medan
Authors: Munte Sonni Willi , Fadilah Risydah , Lubis Rahmi
Published: November 2022

This study uses a quantitative approach, with the sampling technique used is accidental sampling. The population in this study amounted to 216 and the sample from class VIII was 54 which was divided into 2 groups, namely 27 data from each group. The analytical method used to analyze the data obtained in this study uses the Mann Whitney U analysis method. This type of research uses the theoretical basis of learning motivation and interest in learning based on aspects of the theory of Martaniah (2006) and Slameto (2013). The results of this study indicate that the significance value of Mann Whitney U is 0.924, which means that the difference between learning motivation in students who study online and offline is rejected. Thus, the results of the study in the interest in learning group showed the significance value of Mann Whitney U was obtained at 0.808, which means that there is no difference between students' interest in learning when studying online and offline, meaning that this study was rejected because it was not in accordance with the initial hypothesis.
Perlindungan Hukum terhadap Hak Pendesain Industri Atas Gugatan Pembatalan Pendaftaran Desain Industri (Studi Putusan MA No. 407.K/PDT.SUS/HKI)
Authors: Nugraha Aga Rudiansyah , Nadirah Ida , Limbong Ferry Susanto
Published: November 2022

The purpose of this study is an attempt to analyze the legal protection of industrial design rights over lawsuits for cancellation of industrial design registrations. The research method used is using normative legal research methods with literature study data collection techniques, the analysis of this research is decision analysis. The result of this research is that the legal protection for the rights of industrial designers who have registered for the lawsuit for the cancellation of the registration of industrial designs is that the legal protection against the lawsuit for cancellation can be given through the registration mechanism. Protection can be obtained if an industrial design has been registered. This makes it easier to prove and protect even though the principle is from the emergence of industrial design matters. An industrial design right certificate can be issued at the Director General of Intellectual Property Rights which has an important role as proof of ownership for industrial design rights so that it does not have an element of novelty. The conclusion of this study is the legal considerations of the Supreme Court judges on the lawsuit for the cancellation of industrial design rights which have been registered in the Supreme Court's decision no. 407.K/PDT.SUS/HKI/2019 has fulfilled a sense of justice because it does not have a juridical basis and provides legal protection to registered industrial design rights as well as legal certainty if the plaintiff who files a lawsuit for the cancellation of the registered industrial design right cannot prove that the industrial design rights are in accordance with the applicable laws and regulations.
Pengaruh Disiplin Kerja dan Motivasi Kerja terhadap Kinerja Aparatur Sipil Negara pada Sekretariat Dewan Perwakilan Rakyat Kota (DPRK) Subulussalam
Authors: Pratama Tio Harry , Purba Amir , Kusmanto Heri
Published: November 2022

This study aims to determine the effect of work discipline and work motivation on the performance of ASN at the Secretariat of DPRK Subulussalam. The hypothesis proposed is that work discipline and work motivation have a significant effect on the performance of ASN at the DPRK Subulussalam Secretariat. The variables studied consisted of work discipline and work motivation as independent variables and performance as the dependent variable. The method of collecting data is by means of a list of questions. Method of data analysis using multiple linear regression method. The results showed that work discipline had a positive and significant effect on the performance of the ASN Secretariat of DPRK Subulussalam. The better the employee's work discipline, the higher the performanceThe variables of work discipline and work motivation together have a significant effect on the performance of the ASN Secretariat of DPRK Subulussalam. Variations in employee performance can be explained by work discipline and motivation of 95.00%, while the remaining 5.00% is explained by other factors, such as communication, leadership and other factors that are not explained in this research model.
Implementasi Kebijakan Asean-China Free Trade Area (ACFTA) dalam Meningkatkan Kualitas Pelayanan Kepabeanan Belawan, Sumatera Utara
Authors: Suryanto Fajar , Hartono Budi , Dwiana Ressi
Published: November 2022

This study aims to determine the implementation of the ACFTA policy and the factors that influence the implementation at the Medium Customs Type, Customs and Excise Controlling and Servicing Office of Belawan, North Sumatra. The method used is descriptive qualitative with data collection is done through observation, interviews and documentation. Meanwhile the data analysis techniques used are data collection, data reduction, data presentation, and drawing conclusions. Based on the results of the study, it is known that the implementation of the Asean-China Free Trade Area (ACFTA) Policy in Improving the Quality of Services for Medium Customs Type, Customs and Excise Controlling and Servicing Office of Belawan, North Sumatra, North Sumatra still need improvement because communication and bureaucratic structure have not gone well, which is influenced by This is due to the absence of Standard Operating Procedures (SOP), wide fragmentation, different understandings between employees, the absence of special channels related to handling COO constraints, limited socialization and competence of Information Services officers. Meanwhile, those that support implementation are Disposition and Resources which are influenced by organizational culture factors, incentives, infrastructure, internal control, age, information disclosure and performance contracts.
Kualitas Pelayanan Pegawai dalam Pembuatan E-KTP di Dinas Kependudukan dan Pencatatan Sipil Kutacane, Aceh Tenggara
Authors: Rifaldi Rifaldi , Harahap R. Hamdani , Hartono Budi
Published: November 2022

The purpose of this paper is to analyze the quality of E-KTP public services at the Southeast Aceh Regency Population and Civil Registration Service, and the two factors that hinder the E-KTP service at the Southeast Aceh Regency Population and Civil Registration Service. The method used in this study is descriptive with qualitative research instruments with observations, documentation studies and interviews. While the data analysis used descriptive analysis. The results showed that the quality of E-KTP public services which refers to Zeithaml's theory from the tangible dimension (physical evidence/infrastructure), realibility (reliability), responsiveness (responsiveness), assurance (guarantee), empathy (empathy) shows, the quality of public services E-KTP at the population and civil registration office of Southeast Aceh Regency has been running but is still not good or still not optimal. The inhibiting factors for E-KTP public services at Disdukcapil include inadequate human resources, limited financial resources, inadequate facilities and infrastructure, and lack of employee commitment. To improve the quality of public services, the E-KTP Disdukcapil must improve infrastructure, place employees in accordance with competence, increase employee discipline, and in service there should be no discrimination and prioritize service users/community.
Penegakan Hukum Tindak Pidana Pencurian dengan Kekerasan di Wilayah Hukum Kepolisian Sektor Medan Labuhan
Authors: Rahmadysah Andi , Ramadhan M. Citra , Zulyadi Rizkan
Published: November 2022

This study aims to determine the legal regulation of criminal acts with violence in the Indonesian legal system, the obstacles and efforts of the Medan Labuhan Sector Police in eradicating the crime of theft with violence. The research method used is normative juridical with a qualitative approach. The results of the study found that the regulation of the crime of theft with violence is regulated in Article 365 of the Criminal Code, and the crime of theft with violence is included in the category of traditional crimes that are disturbing to the community. There are two obstacles, namely internal obstacles consisting of the lack of human resources (HR) budget for investigations and investigations, minimal Crime facilities or facilities, Members of the Criminal Investigation Unit of the Medan Labuhan Police who always exchange / move to other places (Mutations). External factors, namely the culture of low community legal compliance, weak synergistic institutional relations, wide and high population, urbanization, the influence of narcotics and gambling that occur in the Medan Labuhan sub-district. Non-penal efforts are carried out by taking pre-emptive and preventive actions, while the penal efforts carried out by the Medan Labuhan Police are to carry out investigations, examinations, detentions, and arrests as well as investigations by applying criminal law as the ultimum remedium for criminal law enforcement.
Peran Dukungan Keluarga dan Stres Kerja terhadap Work – life balance pada Paramedis Keperawatan Wanita di Rumah Sakit Kota Medan
Authors: Fatimah Putri , Effendy Sjahril , Lubis Rahmi
Published: November 2022

The research aims to examine the role of family support and job stress to work – life balance among women nursing paramedic at Medan city hospital. This research used quantitative method. Total 324 women nursing paramedic at Medan city hospital participated in this research. The measurement conducted by using family support scale, job stress scale and work – life balance scale. Data on this research was analyzed using regression test. The results of this research show that there was the role of family support and job stress to work – life balance among women nursing paramedic at Medan city hospital cause statistic shows that F value 90.602 > F table 19.493 and p = 0,000 < 0,050. Another result this research approve that there was the role of family support to work – life balance among women nursing paramedic at Medan city hospital cause statistic shows that T value 10.910 > T table 1.967 and p = 0,000 < 0,050. and result this research approve that there was the role of job stress to work – life balance among women nursing paramedic at Medan city hospital cause statistic shows that T value -8.260 > T table 1.967 and p = 0,000 < 0,050. Another result is perceived family support of women nursing paramedic at Medan city hospital categorized as high, experienced job stress women nursing paramedic at Medan city hospital categorized as high and work – life balance of women nursing paramedic at Medan city hospital categorized as low. Therefore, it is recommended that further research be carried out with qualitative methods or mixed design and consider other variables
Sentimento de comunidade e integração social de jovens camponeses no ensino superior
Authors: Silva Alexsandra Maria Sousa , Morais Ximenes Verônica
Published: November 2022

O objetivo foi compreender como se desenvolve o sentimento de comunidade no contexto rural e a integração social dos jovens na universidade. O método foi misto. Utilizou-se a Escala de Integração Social no Ensino Superior – Revisada e Aumentada (EISES-R), a Escala de Sentimento de Comunidade e entrevistas semiestruturadas. Os participantes foram jovens camponeses regularmente matriculados em uma instituição de ensino superior. Os dados foram analisados por meio do SPSS 2.1, e do Atlas ti 5.2. O sentimento de comunidade pode sofrer interferências da migração, no entanto não guarda relações com a inserção desse jovem na universidade.
Exegese et dialectique chez Plotin: quelques remarques methodologiques
Authors: Marsola Mauricio Pagotto
Published: November 2022

No tratado 10 (V 1), 8, ao examinar a questão da constituição das hipóstases inteligíveis, Plotino observa que tais teses não são novas, mas há muito enunciadas pelos filósofos anteriores e notadamente por Platão. De tal modo, sua investigação acerta de tais temas constitui-se como uma exegese dos antigos e dos diálogos platônicos. No início da interrogação acerca da eternidade e do tempo no tratado 45 (III 7), Plotino observa a necessidade de examinar o que os antigos filósofos disseram acerca da temática investigada, propondo um exame doxográfico a fim de que se possa obter “por si mesmo” uma compreensão adequada sobre o tempo a partir de seu paradigma, a eternidade. Nesse sentido, nossa proposta é de elaborar uma breve investigação acerca da possibilidade de articulação desses dois textos plotinianos por meio de alguns elementos presentes no tratado 20 (I 3), Sobre a dialética. De tal modo, pretende-se obter uma aproximação de alguns procedimentos metodológicos do pensamento de Plotino.

 

Palavras-chave: Exegese, Dialética, Método Filosófico, Leitura dos Antigos, Plotino.
Sementes para uma leitura transcendental da filosofia do neoplatonismo tardio
Authors: Lima Danillo Costa
Published: November 2022

Segundo uma leitura bem estabelecida da história da filosofia, a “revolução copernicana” ou “virada transcendental” que ocorre na filosofia moderna, atingindo maturidade no pensamento de Immanuel Kant, teria abolido a possibilidade da metafísica como ciência. Vemos, no entanto, imediatamente em seguida à crítica kantiana o florescimento de um novo modo de pensar a disciplina filosófica da metafísica em chave transcendental, já purificada pela crítica kantiana: o que o scholar Paul Redding chama de ‘idealismo transcendental forte’. Neste artigo, investigo algumas sementes que possibilitam pensar no Neoplatonismo Tardio de Proclo como antecipando alguns elementos dessa abordagem comumente atribuída exclusivamente a metafísicos pós-kantianos.

 

Palavras-chave: Neoplatonismo, Proclo, Idealismo Transcendental, Metafísica.
O estatuto da vida contemplativa e ativa na mística especulativa de Mestre Eckhart com base no Sermão 86, a excelência de Marta sobre Maria
Authors: Alves Moises , Calixto Pedro
Published: November 2022

O seguinte artigo tem como objetivo apresentar a interpretação realizada pelo filósofo e místico alemão Mestre Eckhart, das figuras de Marta e Maria no sermão de número 86 A Excelência de Marta sobre Maria. Apoiado neste sermão, faremos algumas análises filosóficas dos conceitos de vida contemplativa e vida ativa, pois compreendemos que ao realizar a interpretação da superioridade de Marta sobre Maria, Mestre Eckhart estabelece um novo paradigma interpretativo da vida contemplativa e ativa na filosofia medieval.

Palavras-chaves: Mestre Eckhart. Mística. Vida contemplativa. Vida ativa. Marta e Maria.