bluuebunny/crossref_metadata_2025 huggingface dataset:
Obtención de biomodelos personalizados para el análisis mecánico estructural de hueso trabecular con y sin porosidad
Authors: Sánchez-Cervantes Arturo , Urriolagoitia-Sosa Guillermo , Romero-Ángeles Beatriz , Maya-Anaya Daniel , Germán-Carcaño Jesús Manuel , Urriolagoitia-Calderón Guillermo Manuel
Published: February 2025

Las nuevas tecnologías computacionales y los avances en ingeniería han permitido desarrollar biomodelos numéricos para la simulación de sistemas biológicos (huesos). Estos modelos matemáticos permitirán realizar estudios más detallados para diagnosticar a tiempo afecciones (osteoporosis). La biomecánica se encarga de la descripción y estudio de los componentes mecánicos, además de encargarse del estudio, análisis y descripción de los movimientos del cuerpo humano. Con el diseño de biomodelos numéricos que tengan características que se asemejen a la estructura real del hueso y el uso de elementos finitos, los resultados serán muy cercanos a las condiciones reales del cuerpo humano. El análisis numérico utilizado para simular condiciones específicas es de gran ayuda para determinar tratamientos médicos o sustituir elementos biológicos por prótesis.
Análisis microbiológico de harina de grillo de una marca comercial mexicana
Authors: Fuentes-Guardiola Lucia Teresa , García-Martínez Oswaldo , Castrejón-Antonio Jesús Enrique , Landeros-Gálvez Elsa Carolina , Ochoa-Fuentes Yisa María
Published: February 2025

Los insectos como parte de la alimentación humana han tenido gran auge en los últimos años dadas las ventajas que ofrece, tanto nutricionales como su impacto mínimo al medio ambiente. Al ser una fuente alternativa de alimentación relativamente nueva para la mayoría de la población del mundo; aún no se encuentra regulada en lo que a su producción, procesamiento y comercialización respecta, por lo que tampoco existen protocolos que aseguren la inocuidad de los mismos. En este estudio se realizó un análisis microbiológico a una marca comercial de harina de grillo (Acheta domesticus L.) disponible en plataformas de venta en línea en México. Se analizaron tres lotes distintos y se obtuvieron conteos por debajo de los límites señalados por la NOM-247-SSA1-2008 de mesófilos aerobios y de mohos; las pruebas para coliformes totales y fecales resultaron negativas y se detectó la presencia de Salmonella spp.
Supervivencia por cáncer de mama en mujeres beneficiarias del seguro popular en San Luis Potosí, México
Authors: Terán-Figueroa Yolanda , García-Díaz Janeth , Gutiérrez-Enríquez Sandra Olimpia , Alcántara-Quintana Luz Eugenia , Luna-Arias Juan Pedro , Gaytán-Hernández Darío
Published: February 2025

Se analizó la supervivencia en pacientes con cáncer de mama beneficiarias del Seguro de Salud Popular en San Luis Potosí, de 2007-2012. Estudio cuantitativo observacional, transversal y retrospectivo, incluyó 502 casos de cáncer de mama. Se utilizaron curvas de Kaplan-Meier, prueba de log rango (Mantel-Cox) y un modelo multivariado mediante regresión de Cox. Hubo mayor supervivencia en mujeres con estatus receptor de estrógenos positivo que las de negativo. Las de receptor de estrógeno o receptor de progesterona positivo, que recibieron una dosis más alta de radioterapia, estaban en un decil más alto del nivel socioeconómico, tuvieron un menor riesgo de morir en comparación con aquellas que no lo fueron; las de estadio IIA tuvieron un menor riesgo de morir que las de estadio IV. La supervivencia está relacionada con: estatus receptor de estrógeno y progesterona, estadio del cáncer, nivel educativo, dosis de radioterapia y nivel socioeconómico.
Óptimo técnico y económico en pollos Cobb 500 bajo sistema intensivo
Authors: Velázquez-Villalva Héctor Hugo , Rebollar-Rebollar Samuel
Published: February 2025

El objetivo fue determinar el nivel óptimo técnico y económico en pollos Cobb 500 bajo sistema intensivo a siete semanas, mediante una función de producción polinómica de segundo grado. Los datos provinieron de 168 pollos asignados aleatoriamente en 42 repeticiones con cuatro aves de julio a septiembre de 2023 en el área avícola del Centro Universitario UAEM Temascaltepec. Las variables fueron ganancia de peso semanal y consumo de alimento. La máxima producción y máxima ganancia se obtuvo con 9.9 y 7.0 kilogramos de alimento y un peso vivo final de 3.3 y 3.0 kilogramos. Al nivel óptimo técnico, el costo, ingreso total y ganancia fueron 87.3, 148.5 y 61.2 pesos y al óptimo económico de 61.6, 133.8 y 72.4 pesos, promedio por pollo. Se deduce que el peso máximo del pollo no significó el máximo valor monetario. El avicultor debería vender las aves al peso del nivel óptimo económico.
Uji Aktivitas Antioksidan Daun Sirsak (Annona muricata L) Berdasarkan Tempat Tumbuh
Authors: Mega Yulia  , Halimah Nur
Published: February 2025

Sirsak merupakan tumbuhan tropis yang dapat hidup di dataran tinggi juga di dataran rendah.  Daun ini diketahui memiliki aktivitas antioksidan.  Kandungan metabolit sekunder daun sirsak yaitu alkaloid, fenolik, flavonoid, steroid dan saponin. Lingkungan tempat tumbuh akan mempengaruhi kandungan metabolit sekunder pada tumbuhan yang nantinya akan berpengaruh kepada aktivitas yang dihasilkan. Pada penelitian ini sampel diambil di 2 daerah berbeda yaitu Bukittinggi mewakili dataran tinggi dan Payabungan mewakili dataran rendah. Tujuan penelitian ini adalah untuk mengetahui bagaimana tempat tumbuh memengaruhi aktivitas antioksidan. Metode penelitian yaitu sampel diekstraksi maserasi menggunakan pelarut etanol destilasi. Aktivitas antioksidan diukur menggunakan metode DPPH dengan spektrofotometri UV-Vis dengan standart vitamin C. Dari hasil penelitian diketahui aktivitas antioksidan dengan nilai IC₅₀ untuk ekstrak daun sirsak Bukittinggi sebesar 360,49 ppm dan ekstrak daun sirsak Panyabungan sebesar 804,09 ppm. Kesimpulan bahwa ekstrak daun sirsak Bukittinggi (dataran tinggi) mempunyai nilai aktivitas antioksidan yang lebih kuat dibandingkan ekstrak daun sirsak Panyabungan (dataran rendah).
Uji Efektivitas Ekstrak Etanol Daun Kersen (Mutingia calabura L.) Sebagai Antikolesterol Pada Mencit Putih Jantan (Mus musculus)
Authors: Natasha Adelia , Brata Andy , Muin Dona
Published: February 2025

Hiperkolesterolemia adalah peningkatan kadar kolesterol LDL puasa tanpa disertai peningkatan kadar Trigliserida. Salah satu tanaman yang bermanfaat menurunkan kadar kolesterol yaitu daun kersen (Mutingia calabura L.) diketahui mengadung flavonoid, alkaloid tanin dan saponin. Penelitian bertujuan untuk mengetahui efektivitas ekstrak daun kersen (Mutingia calabura L.)  serta dosis yang efektif dalam menurunkan kadar kolesterol pada mencit putih jantan (Mus musculus). Metode yang digunakan pretest-posttes control grup desain, dibagi menjadi 5 kelompok. K- I sebagai kontrol negatif (Na. CMC 0,5%), K-II sebagai kontrol positif (Simvastatin), K-III sebagai kelompok dosis I (dosis 70mg/KgBB), K-IV sebagai kelompok dosis II (dosis 140mg/KgBB), K-V sebagai kelompok III  (dosis 210mg/KgBB). Penginduksi diberikan selama 7 hari, kemudian dilanjutkan dengan pemberian perlakuan selama 7 hari terhitung setelah pemberian penginduksi. Data yang diperoleh dianalisis menggunakan One-Way ANOVA didapatkan nilai Sig. p=0,000 <0,05, Kemudian dilanjutkan dengan uji Post Hoc Duncan. Dari penelitian diperoleh bahwa ekstrak etanol daun kersen pada dosis III, II dan I secara berturut-turut dengan persentase penurunan 30,4%, 29,16%, dan 21,66 % memiliki efektivitas dalam menurunkan kadar kolesterol pada mencit putih jantan (Mus musculus). Disimpulkan bahwa ekstrak etanol daun kersen (Mutingia calabura L.) memiliki efektivitas sebagai penurun kadar kolesterol dengan dosis yang efektif adalah dosis III.
Pola Penyimpanan Obat High Alert Pada Rumah Sakit Di Kota Bengkulu
Authors: Iqoranny Susilo Avrilya , Khasanah Heti Rais , Febrianti Penny
Published: February 2025

Obat High Alert merupakan salah satu golongan obat yang dalam pemberiannya perlu kewaspadaan tinggi bagi tenaga farmasi karena sering menyebabkan terjadi kesalahan-kesalahan serius dan obat yang berisiko tinggi menyebabkan Reaksi Obat yang Tidak Diinginkan (ROTD). Untuk menghindari kesalahan-kesalahan pemberian obat yang terjadi maka, pengaturan penyimpanan obat untuk obat High Alert harus diperhatikan, karena kesalahan pengobatan terkadang terjadi karena kesalahan pengambilan obat dari rak penyimpanan obat. Penelitian dilakukan untuk melihat kesesuaian penyimpanan obat High Alert berdasarkan standar prosedur operasional yang ada di Rumah Sakit Kota Bengkulu. Pada penelitian ini digunakan metode observasi langsung pada Rumah Sakit yang dijadikan sampel dengan menggunakan lembar observasi melalui sistem check list, kemudian dilakukan perhitungan persentase standar penyimpanan obat High Alert. Hasil penelitian menunjukan kesesuaian penyimpanan obat High Alert berdasarkan Standar Operasional Penyimpanan di Rumah Sakit Kota Bengkulu untuk kriteria pelabelan berwarna merah pada kemasan maupun tempat obat (40%), penyimpanan secara terpisah (60%), FEFO/FIFO (100%), Alfabetis (80%), Jenis Sediaan Obat (100%), Suhu (100%). Pada penilaian kesesuaian penyimpanan obat High Alert. Pada indikator penyimpanan berdasarkan pelabelan berwarna merah pada kemasan maupun tempat obat masih terdapat obat yang tidak berlabel dan pada indikator penyimpanan secara terpisah diberikan jarak 1 wadah masih terdapat obat High Alert dalam kategori LASA yang disimpan secara berdekatan.
Radiopharmaceuticals Based on Somatostatin Analogs and Technetium-99m Radionuclide for Diagnosis of Neuroendocrine Tumors: a Literature Review
Authors:   A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Centre, Obninsk, Russia, Tishchenko V.K. , Vlasova O.P. ,   A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Centre, Obninsk, Russia,   National Medical Research Radiological Center, Moscow, Russia, Ivanov S.A. ,   A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Centre, Obninsk, Russia,   Рeoples Friendship University of Russia, Moscow, Russia, Kaprin A.D. ,   National Medical Research Radiological Center, Moscow, Russia,   Рeoples Friendship University of Russia, Moscow, Russia,   P.A. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Moscow, Russia
Published: February 2025

Introduction

Somatostatin receptor imaging capabilities

Radiopharmaceuticals based on somatostatin receptors agonists and technetium-99m

Radiopharmaceuticals based on somatostatin receptors antagonists and technetium-99m

Conclusion
Implementasi Kebijakan Pencegahan Pencemaran Dan Kerusakan Lingkungan
Authors: Hayati Winta , Ismayani Author
Published: February 2025

Tanggung jawab pengelolaan lingkungan berada pada pemerintah dalam arti tidak diserahkan kepada orang perorang warga negara atau menjadi Hukum Perdata. Tanggung jawab pengelolaan lingkungan ada pada Pemerintah yang membawa konsekuensi terhadap kelembagaan dan kewenangan bagi pemerintah untuk melakukan pengelolaan lingkungan menjadi bagian dari Hukum Administrasi. Metode penelitian yang digunakan dalam penelitian ini adalah penelitian normatif, menekankan fungsi AMDAL sebagai instrumen pencegahan pencemaran dan kerusakan lingkungan dalam penelitian normatif, pemprosesan bahan hukum secara sistematisasi hukum. Bahan-bahan hukum kemudian dianalisis secara kualitatif, menganalisis dengan berpikir sistematis untuk memberikan jawaban dari masalah. Program-program di bidang penaatan lingkungan ini mencakup: pengendalian pencemaran dan perusakan lingkungan dan pengembangan kapasitas pengelolaan. Dengan adanya perkembangan kehidupan, tentunya kebutuhan juga akan sangat berkembang termasuk kebutuhan eksploitasi sumber daya alam yang berlebihan, kerusakan lingkungan karena faktor manusia ini bisa berupa adanya penebangan secara liar yang menyebabkan kebakaran hutan, banjir dan tanah longsor, dan pembuangan sampah di sembarangan tempat yang dapat merusak ekosistem darat maupun laut. instrumen dalam izin lingkungan meliputi Analisis Mengenai Dampak Lingkungan Hidup, Upaya Pengelolaan Lingkungan Hidup, dan Upaya Pemantauan Lingkungan Hidup (UKL/UPL). Prinsip dari perizinan lingkungan sebagaimana diatur dalam UUPPLH pada dasarnya mengamanatkan pada setiap usaha dan/atau kegiatan yang wajib memiliki dokumen Amdal atau UKL-UPL wajib memiliki izin lingkungan. Upaya utama yang harus dilakukan dalam pengelolaan lingkungan hidup adalah pencegahan pencemaran dan kerusakan lingkungan, dimana dalam pasal 1 angka (2) UUPPLH menyatakan bahwa salah satu upaya pencegahan adalah dengan melakukan pengawasan yang sistematis dan terpadu terhadap izin lingkungan.
Pengaruh Lingkungan dan Beban Kerja terhadap Kinerja Pegawai PDAM Tirta Silaupiasa Kisaran
Authors: Manja Erni
Published: February 2025

Penelitian ini bertujuan untuk menganalisis pengaruh lingkungan kerja dan beban kerja terhadap kinerja pegawai PDAM Tirta Silaupiasa Kisaran. Penelitian ini menggunakan metode kuantitatif dengan sifat asosiatif, di mana populasi yang digunakan adalah pegawai PDAM Tirta Silaupiasa Kisaran. Analisis data dilakukan menggunakan regresi linier berganda dengan alat uji SPSS 27.0.
Hasil penelitian menunjukkan bahwa lingkungan kerja memiliki pengaruh yang signifikan terhadap kinerja pegawai, dengan nilai t-hitung sebesar 7,606 dan signifikansi 0,000. Setiap peningkatan satu satuan dalam lingkungan kerja akan meningkatkan kinerja pegawai sebesar 1,671 satuan. Sementara itu, beban kerja tidak memiliki pengaruh yang signifikan terhadap kinerja pegawai, dengan nilai t-hitung sebesar 1,841 dan signifikansi 0,072. Uji F menunjukkan bahwa lingkungan kerja dan beban kerja secara simultan berpengaruh signifikan terhadap kinerja pegawai dengan nilai F-hitung sebesar 37,145 dan signifikansi 0,000. Nilai Adjusted R Square sebesar 0,616 menunjukkan bahwa 61,6% variasi dalam kinerja pegawai dapat dijelaskan oleh lingkungan kerja dan beban kerja, sedangkan sisanya 38,4% dipengaruhi oleh faktor lain di luar model penelitian.
Dengan hasil penelitian ini diharapkan manajemen PDAM Tirta Silaupiasa Kisaran lebih meningkatkan kualitas lingkungan kerja untuk mendorong kinerja pegawai. Selain itu, penelitian selanjutnya dapat memasukkan variabel lain yang berpotensi memengaruhi kinerja pegawai guna memperoleh hasil yang lebih komprehensif.
ANALISIS PENGARUH RASIO KEUANGAN TERHADAP PERTUMBUHAN LABA ( STUDI KASUS PADA PERUSAHAAN CONSUMER GOODS)
Authors: Bahagia India
Published: February 2025

This study uses independent variables, namely Current Ratio, Debt to Asset Ratio and Net Profit Margin with the dependent variable namely Profit Growth. The object of research is Consumer Goods companies listed on the Indonesia Stock Exchange for the period 2020 – 2022. The sample selection was carried out using a purposive sampling technique and a sample of 33 companies was obtained. The purposes of this study are: Test and analyze the effect of the current ratio on profit growth during the Covid-19 pandemic in consumer goods companies listed on the Indonesia Stock Exchange for the period 2020 – 2022. Test and analyze the effect of the debt to asset ratio on profit growth during the pandemic covid-19 in consumer goods companies listed on the Indonesia Stock Exchange for the 2020 – 2022 period. Test and analyze the effect of net profit margin on profit growth during the Covid-19 pandemic for consumer goods companies listed on the Indonesia Stock Exchange for the 2020 – 2022 period. After conducting research using the multiple linear analysis method, it can be concluded: 1. Current Ratio (CR) has no effect on company profit growth during the co-19 pandemic. 2. Debt to Asset Ratio (DAR) has no effect on company profit growth during the co-19 pandemic. 3. Net Profit Margin (NPM) has no effect on company profit growth during the co-19 pandemic.
A gestão do pré-natal na atenção primária em saúde: Um relato de experiência
Authors: Andrade Filho Antonio Carlos Farias de , Cavalcante Sônia Ávila , Moura Lucas Eliel Beserra , Weyne Karla Maryana Lima Loiola , Campos Jocileide Sales
Published: February 2025

Este artigo tem como objetivo relatar os resultados da experiência formativa vivenciada por alunos do curso de Medicina do Centro Universitário Unichristus. O intuito foi identificar situações problemas com estabelecimento de prioridades por meio de critérios epidemiológicos, nas Unidades de Atenção Primária à Saúde (UAPS), no município de Fortaleza. Este projeto foi dividido em três etapas. Primeiramente realizou-se uma Oficina de Gestão da Atenção Primária à Saúde com profissionais da Secretaria Municipal de Saúde, professores e alunos. Entre os temas elencados pelos grupos de trabalho, destacou-se como um dos mais prevalentes a Baixa Adesão de Pré-Natal. No segundo momento, sob orientação dos preceptores da UAPS, ficou definido que as atividades de intervenção ocorreriam junto aos Agentes Comunitários de Saúde (ACSs). Foi elaborado um formulário relativo à identificação e solução dos problemas encontrados na UAPS. Além disso, realizou-se uma aula sobre pré-natal, gestação e contracepção para os ACSs. E por fim, foi conversado com a equipe gestora da Unidade acerca dos indicadores em saúde do equipamento em questão e das demandas dos usuários, assim como dos serviços realizados pela equipe multiprofissional e os resultados alcançados. Na última etapa da atividade, em reunião na Faculdade, foram discutidos os resultados das intervenções realizadas. É possível afirmar que somando-se ao rico aprendizado dos quatro meses de atendimentos nas UAPS, participar dessa experiência formativa, possibilitou uma apropriação maior dos conhecimentos relativos à Política Nacional de Atenção Básica, buscando identificar demandas e planejar ações interventivas em saúde, tendo como referência os indicadores locais e nacionais.
Perfil clínico epidemiológico da lesão medular em centro de reabilitação em Teresina, Piauí
Authors: Silva Laura Ravena Veloso , Peres Kalyna Alves , Leal Noélia Maria de Sousa , Mendes Alice Lima Rosa , Melo Suely Moura , Borges Andressa Mayara Bastos Abreu , Pimentel Leonardo Halley Carvalho
Published: February 2025

O objetivo desse estudo foi avaliar as causas e etiologias das lesões, identificar o perfil clínico e demográfico dos pacientes, além de comparar a evolução clínica dos diferentes tipos de lesões. Para isso, foi realizado um estudo transversal, descritivo de delineamento quantitativo, por meio da análise de prontuários médicos de pacientes atendidos em um Centro de Reabilitação em Teresina-PI no período compreendido entre novembro de 2023 a fevereiro de 2024. Foram coletados dos prontuários, aspectos como o perfil clínico e as variáveis sociodemográficas, tais como: gênero, raça, estado civil e faixa etária. Foram analisados 51 casos na capital do Piauí. A prevalência foi de indivíduos do sexo masculino com a faixa etária de 18 a 30 anos de idade. Observou-se também que a lesão traumática foi a mais prevalente na amostra com 45 casos. Foi possível notar que houve uma variação no nível da lesão, sendo 18 casos em nível cervical, 13 em nível lombar e 20 em nível torácico. Em relação à incontinência urinária, notou-se que a maior parte dos pacientes apresentou essa condição na admissão. Além disso, o principal mecanismo de lesão medular nos pacientes analisados foi por meio de acidentes de trânsito, seguido pela lesão medular ocasionada por ferimentos por arma de fogo. Concluiu-se que na amostra analisada, houve maior prevalência de lesão em nível torácico, acompanhado de incontinência urinária na admissão, e a principal causa foi traumática (acidentes de trânsito).
Neurogenomics at scale
Authors:   , Hop Paul Jurriaan
Published: February 2025

The work described in this thesis sought to uncover genetic and epigenetic factors contributing to neurodegenerative disease, identify genes involved in epigenetic regulation, and develop methodology and tools to facilitate this research. This work culminated in the discovery of DNA methylation signatures associated with ALS, novel rare variants contributing to ALS and Parkinson’s disease, and genes involved in DNA methylation regulation. Additionally, it describes the development of methodology and R packages to enhance the quality control and analysis of large-scale DNA methylation and sequencing datasets.
Incidental Findings on MRI Brain Imaging in Pilots from the Canadian White Matter Hyperintensity Study
Authors: Danho Sharef , Saary Joan
Published: February 2025

BACKGROUND: Incidental neuroanatomical findings are commonly identified during brain MRI completed clinically, for research, or for other purposes, including aircrew screening. Such findings range from benign to pathological and some may be disqualifying for flight duties. We present a series of cases with incidental neuroanatomical findings identified in Royal Canadian Armed Forces (RCAF) aircrew during the Canadian White Matter Hyperintensity research study, and the subsequent aeromedical evaluation undertaken to manage them. Our study group performed 48 brain MRI scans on 42 RCAF pilots and 6 aviation physiology technicians and parajumpers. Participants were men ages 25–70 with a mean age of 39.

CASE SERIES: Incidental neuroanatomical findings were detected in four pilots, with six distinct findings (four vascular abnormalities, one arachnoid cyst, and one nonspecific nodule). All cases were asymptomatic. After evaluation of the findings of each case by a medical consortium, including an aeromedical neurologist, all pilots were cleared for ongoing duties with no restrictions.

DISCUSSION: The rate and nature of incidental findings in RCAF members in the White Matter Hyperintensity Study is consistent with that found in both the general population and in other military pilot populations. There is no international standard for screening or management of incidental findings; therefore, we recommend an approach that involves a case-by-case evaluation of the findings by a multidisciplinary medical team, with careful identification and consideration for high-risk features.

Danho S, Saary J. Incidental findings on MRI brain imaging in pilots from the Canadian White Matter Hyperintensity Study. Aerosp Med Hum Perform. 2025; 96(3):255–259.
Cochlear Implants in Aviators
Authors: Schall David G.
Published: February 2025

INTRODUCTION: Cochlear implants (CIs) have revolutionized the management of deafness. Combined with newborn screening, children are being identified earlier and rehabilitated with CIs, allowing them to be mainstreamed in the education system. The aviation community has begun to see a new generation of pilots who are now seeking careers in aviation with the use of CI.

METHODS: A literature review using the Ovid Medline database was conducted. A search for airmen within the Federal Aviation Administration (FAA) Airman Medical Certification System with a diagnostic code for CIs was reviewed up to the year 2021.

RESULTS: There are no studies to date documenting airmen with CIs. The FAA has certified 42 airmen with Cis, including 10 with First Class Medical Certificates. Airmen with CIs have been able to successfully pursue careers in aviation from general aviation to commercial airline pilot in the United States.

DISCUSSION: CIs are used for both bilateral and single-sided deafness and are becoming more prevalent within the general population. Applicants with CIs are now seeking careers in aviation in increasing numbers. The FAA has successfully certified airmen from Class III to Class I airline pilots. It requires appropriate evaluation and screening, including a medical flight test to document adequate communication, recognition of alarms within the cockpit, and the ability to communicate with air traffic control.

Schall DG. Cochlear implants in aviators. Aerosp Med Hum Perform. 2025; 96(3):260–263.
Actigraphy-Driven Biomathematical Fatigue Modeling in British Military Rotary-Wing Pilots
Authors: Pelham Andrew , Van Tongeren Martie , Arnold Heidi , Cocco Pierluigi
Published: February 2025

INTRODUCTION: A study of fatigue in British military rotary-wing pilots was conducted to determine the utility of actigraphy-driven fatigue modeling in the military rotary-wing environment.

METHODS: A total of 48 pilots were recruited across the 3 military services of the United Kingdom. Objective fatigue was predicted using wearable actigraphy and the Sleep Activity Fatigue Task Effectiveness (SAFTE) fatigue model. Subjective data were collected from daily questionnaires completed by the study subjects, including an assessment of their own fatigue level using Samn-Perelli Scale scores. The relationship between these two data sets was then assessed with correlation and linear regression modeling.

RESULTS: There were 38 men and 2 women recruited. The mean age was 36.4 yr (standard deviation ± 6.5, range 26–52 yr). In total, 200 flights were undertaken, with a mean flight time of 156 min (± 77.1, range 15–480); the mean landing time of these flights was 18:45 (range 11:00–02:30). The data included 37 d of pilots deployed on exercise. SAFTE scores were shown to decline for night flying, especially if landing after 22:00. With increasing subjective levels of fatigue, the relationship between SAFTE and Samn-Perelli Scale scores in subjects weakened.

DISCUSSION: Actigraphy-driven modeling has a role in specific aspects of military rotary-wing aviation. Consideration should be given to its use in specific scenarios, including night-flying and flights undertaken when deployed on exercise.

Pelham A, Van Tongeren M, Arnold H, Cocco P. Actigraphy-driven biomathematical fatigue modeling in British military rotary-wing pilots. Aerosp Med Hum Perform. 2025; 96(3):206–211.
Occupational Physical Requirements for Astronauts
Authors: St-Martin Philippe , Lalonde François , Bouchard-Lévesque Félix , Dionne Isabelle J.
Published: February 2025

INTRODUCTION: Through the Artemis program, space agencies and astronauts are preparing for extended durations in space and on planetary surfaces, expanding their occupational tasks. Although standardized laboratory tests are effective in assessing health and mitigating deconditioning, their reliability in forecasting occupational performance is uncertain. Consequently, a recent shift in exercise testing has emerged, shifting focus from health-oriented criteria to operational performance. This involves identifying the physical demands associated with components of an astronaut’s tasks and determining a minimum level of performance, referred to as Physical Employment Standards. The aim of this systematic review is to provide an updated overview of the scientific literature on astronaut occupational tasks and physiological requirements.

METHODS: A search was conducted spanning from 1970 to October 2023. Articles meeting the inclusion criteria underwent screening using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for an evidence-based systematic review.

RESULTS: There were 10 studies selected for inclusion in the current review and pertinent information was extracted. There were 14 tasks physiologically assessed: ambulation on various terrains, physical abilities field, device operations/activity board, re-entry and landing, hatch opening, capsule egress, recovery from fall, jump down, ladder climb, material transfer, emergency crewmember drag, hand drilling, construction wrenching, and upper-limb weighted tasks.

DISCUSSION: Physical Employment Standards for astronauts have yet to be established; however, certain tasks have been identified, enabling tailored occupational assessments for astronauts, increasingly recognized as tactical athletes. The results of this literature review lay the foundations for scientific task analysis and the development of operational physical tests for astronauts.

St-Martin P, Lalonde F, Bouchard-Lévesque F, Dionne IJ. Occupational physical requirements for astronauts. Aerosp Med Hum Perform. 2025; 96(3):234–250.
Non trivial zeros of the Riemann zeta function
Authors: OUKIL Walid
Published: February 2025

In this paper, we consider the representation of the Riemann zeta function $\zeta$ defined by Abel's summation formula. We show that $|\zeta(s)|\neq 0$ for any point $s\in \mathbb{C}$ such that $\Re(s)\in (\frac{1}{2},1)$.
GEFT Scheduling to Maximize Value of Current Infrastructure and Upside Potential
Authors: Suppes Adam , Suppes Galen
Published: February 2025

Passenger end-to-end transit times can be reduced by more than 50% using existing rail infrastructure when scheduling is simultaneously advanced with implementation of multimodal ground-effect flight transit (GEFT) railcars. Initial implementations would increase ridership and better utilize existing trains with an emphasis on outskirt suburban locations with as few as three new vehicles. The more-evolved modes of operation use dynamically-forming trains of single railcars traveling down the line as a wave with single railcars leaving and joining the wave; it is made possible by ground-effect technology that increases speed, energy efficiency, and stealth of single railcars. GEFT attain efficient aerodynamic suspension over railway tracks, reducing both drag and rolling losses toward replacing steel wheels with tires. The aerodynamic suspension reduces stress on tracks toward higher speeds on marginal tracks with tires rather than steel wheels. The tires: a) enable multimodal vehicles to efficiently turn around on roads and slabs, b) expand seamless routing to include both railways and highways, and c) reduce noise.
THE ROLE OF HUMAN RESOURCE MANAGEMENT IN SERVICE QUALITY IMPROVEMENT OF HOTEL BUSINESSES
Authors: Greasidou Maria , Valachis Ioannis
Published: February 2025

In order a hotel business to achieve a long-term quality performance, it should train, empower and actively involve the employees in the service process. Therefore, the involvement of Human Resourse Management (HRM) department is imperative. The purpose of this study is to explore the level that HRM basic approaches are applied by hotels, particularly those fundamental requirements that might enhance quality service provision. Furthermore, the paper is examining the individual and unique characteristics of the hotel units, such as size, categorization etc., in an effort to reveal possible diversions and correlations according to the HRM implemented philosophy. According to the research findings, the examined hotels adopt a range of agreed HR policies and practices that are more likely to create organizations aiming to compete on the basis of high-quality services. Moreover, the hotels that apply greater HRM principles are those of great capacity. This can be explained due to the large number of hotel employees; their number, along with the fact that hospitality is a labour-intensive industry, necessitates HRM practices to play an important role in service quality provision. One more interesting finding arising from this research is that the category of the hotel does not play an important role at the degree that a hotel applies HRM best practices.
Struktur Komunitas Fitoplankton dan Tingkat Pencemaran di Danau Dendam Tak Sudah, Kota Bengkulu
Authors: Putri Inten Diana
Published: February 2025

Dendam Tak Sudah Lake (DDTS) is an aquatic ecosystem and nature reserve located in Dusun Besar Village, Singgaran Pati District, Bengkulu City. Its presence serves not only as a tourist destination and irrigation water supply for rice fields but also as a habitat for phytoplankton. The land use changes around the DDTS Nature Reserve have impacted the water quality of the lake, and phytoplankton are among the biota affected by these pressures. This study aims to assess the phytoplankton community structure and the pollution level in DDTS. The research was conducted by identifying and counting each phytoplankton species found and analyzing water quality. The results of the study showed that the phytoplankton richness in DDTS consisted of 20 species, including 8 species from the Bacillariophyceae class, 6 species from the Chlorophyceae class, 2 species from the Cyanophyceae class, and 4 species from the Euglenophyceae class. The highest phytoplankton abundance was found at the inlet with 1,135.2 individuals/l, followed by the midlet with 1,095.6 individuals/l, and the outlet with 997.2 individuals/l. The diversity index values were high (2.6-2.8), the evenness index was high (0.95-0.96), and dominance was low (0.07-0.08). The saprobic coefficient in DDTS was classified as β-Meso/Oligosaprobic, indicating that the water quality is lightly polluted, with a saprobic index value ranging from 0.6 to 0.87.
Culture-based characterization of gut microbiota in inflammatory bowel disease
Authors: Park Hyunjoon , Yeo Soyoung , Lee Taekyu , Han Yumin , Ryu Chang Beom , Huh Chul Sung
Published: February 2025

Inflammatory bowel disease (IBD) is characterized by disruptions in the gut microbiome. While most studies on gut dysbiosis in IBD rely on sequencing-based methods, we employed a streamlined culturomics approach to obtain a more comprehensive understanding of gut microbiota imbalance in patients with IBD that may not be captured by sequencing alone. A total of 367 bacteria were identified at the species level, including 211 species from ulcerative colitis patients, 164 species from Crohn’s disease (CD) patients, and 263 species from healthy individuals. Consistent with our 16S rRNA gene amplicon sequencing results, a significant decrease in microbial diversity and a severe imbalance, especially in CD patients, were also observed in the culture-based analysis. Our culturomics approach provided additional insights, highlighting dysbiosis in unique anaerobic and Gram-negative species in CD patients. Moreover, species-level findings for Bifidobacterium and Enterobacterales emphasized specific species expansions in IBD patients. Notably, Mediterraneibacter gnavus, Thomasclavelia ramosa, Parabacteroides merdae, and Collinsella aerofaciens are of particular clinical interest due to their correlation with inflammatory biomarkers. This comprehensive analysis underscores the value of integrating a culture-based approach with a genome-based approach to provide complementary insights and therapeutic targets in IBD.
Prevalence and family function associated with suicide-related behaviors in vocational college population of southern China: the mediating role of depression
Authors: Wang He , Zhong Yingyu , Wang Yueyun
Published: February 2025

Background

Suicide is positively associated with a range of psychological risk factors such as family function and depression. However, it remains unclear if depression mediates the association between family function and suicide in Chinese adolescents.

Methods

We enrolled 14263 students from Shenzhen Polytechnic College, China. Family function, depression and suicide were assessed in these students by self-report measures, respectively. With path analysis and logistic regression, the mediating role of depression in the association between family function and suicide was analyzed.

Results

In this study, the detection rate of suicide-related behaviors among vocational school students was 12.19%, among which the detection rates of suicide idea, suicide plan and suicide attempt were 11.59%, 4.26% and 2.70%, respectively. Depression played a significant mediating role in the influence of family function on suicide-related behaviors.

Conclusions

Poor family function might increase the risk of suicide-related behaviors in vocational school students, and this effect was partly realized by affecting their mental health. Improving family function could not only improve adolescent’s psychological status, but also reduce their suicide-related behaviors.
Economic autonomy as a determinant of physical activity behavior in Chinese older adults
Authors: Liu Yuanheng , Luo Xianglin , Xu Hao
Published: February 2025

Background

The physical activity of the old people is affected by many factors, and the economic situation is an important factor affecting the physical activity. However, the relationship between economic autonomy and physical activity patterns among older adult Chinese has not been fully studied.

Objective

To investigate the association between different types of economic autonomy and physical activity patterns among Chinese older adults aged 60 and above.

Methods

Cross-sectional analysis of 1,961 participants from the 2018 China Health and Retirement Longitudinal Study (CHARLS). Economic autonomy was categorized into autonomous and non-autonomous groups. Physical activity was assessed through type, frequency, duration, and purpose, using validated questionnaires.

Results

Economic autonomy showed positive associations with low and moderate-intensity physical activities (p < 0.05). However, economically non-autonomous individuals demonstrated higher participation in high-intensity physical activities, primarily due to work-related demands (78.7%). The frequency of physical activity was significantly different among economic autonomy groups (p < 0.01).
Mind–body therapy for cardiometabolic risk in U.S. middle-aged Black adults: a scoping review
Authors: Martin Danielle A. , Hook Jane , Kim Sunny Wonsun , Larkey Linda , Lee Rebecca E.
Published: February 2025

Background

In the U.S., Black adults do not achieve the same life expectancy as their White counterparts, and this is attributable in large part to the development of cardiovascular disease (CVD). Mind–body therapy (MBT) interventions demonstrate improvements in cardiometabolic risk (CMR) factors that promote CVD, with increased feasibility and acceptability in the general population. Less known is the feasibility, acceptability, and evidence of reduction in CMR factors in the U.S. Black population with MBT.

Purpose

This study aimed to synthesize the current state of research regarding MBT on CMR factors in middle-aged U.S. Black adults and identify gaps in the literature. Research Question 1: What types of studies have been conducted (study design, theoretical framework, and cultural relevance)? and Research Question 2: What is the feasibility and acceptability and effectiveness of MBT in Black adults for CMR reduction?

Methods

Following PRISMA-ScR guidelines, a review of three databases was conducted. Our inclusion criteria were articles that (1) describe empirical research; (2) assessed a MBT intervention in middle-aged (35–64) adults with a minimum of 60% Black adult participants for CMR reduction; and (3) written in English. Independent reviewers selected articles for inclusion and data extraction, with a third reviewer providing consensus.

Results

Fourteen articles met the eligibility criteria (n = 14). Characteristics included randomized controlled trials (8, 57.1%); single-arm (3, 21.0%); mixed methods (3, 21.0%); sample size (17–375); mean age range 43–64; female (6, 42.8%); theoretical framework (4, 28.6%); culturally adapted (7, 50.0%); and studies demonstrating feasibility and/or acceptability (7, 50.0%). Of the seven articles assessing CMR physiologic factors, five studies observed significant improvement. For the 11 studies assessing CMR psychological factors, 6 studies had statistically significant results and 3 studies identified trends toward positive statistical outcomes.

Implication

A growing body of literature across research stages demonstrating acceptability, and feasibility, and evidence of effectiveness for selected outcomes of MBT in middle-aged Black adults with CMR factors shows promise. Future research recommendations include greater recruitment of Black men for MBT studies, larger sample sizes, and utilizing culturally adapted interventions for engaging Black adults in MBT for reduced CMR factors.
The coronal line region of active galactic nuclei
Authors: Rodríguez-Ardila Alberto , Cerqueira-Campos Fernando
Published: February 2025

Forbidden coronal lines has traditionally called the attention due to the high-energy photons required for their production (IP >100 eV, where IP is the ionisation potential of the transitions that originate the line). As such, they are regarded as the most highly ionised component of Active Galactic Nuclei (AGN). For decades, it was thought that they were only formed in the inner portions of the narrow line region (NLR). Nowadays, due to the larger sensitivity of the detectors and the availability of integral field unit (IFU) spectrographs, that emission in addition to the nuclear component is found to be extended up to a few kiloparsecs away from the active centre. In this review, we highlight the most important aspects of the coronal emission and discuss the recent developments in the field. In particular, we emphasize the discovery that they can be used to determine the mass of the central supermassive black hole, to reconstruct the SED, as well as to trace the most energetic feedback component of the ionised gas in AGN.
Impacts of organizational support on rice farmers’ adoption of green production technologies—implications for food security and environmental sustainability
Authors: Zhang Xu , Zhang Yuhan , Liu Yang , Ye Feng , Liao Wenmei
Published: February 2025

Introduction

The relentless focus on maximizing production has exacerbated ecological challenges, including agricultural surface pollution, soil crusting, and farmland degradation, which increasingly threaten sustainable development. Agricultural green production technologies are essential for balancing food security with environmental sustainability.

Methods

This study examines the role of organizational support in fostering farmers’ adoption of agricultural green production technologies, using survey data from 1,426 rice farmers in Jiangxi Province, China. Ordered logit and moderated mediation models reveal a robust positive effect of organizational support on agricultural green production technology adoption, even after addressing endogeneity concerns.

Results and discussion

The findings highlight that the effect of organizational support is more pronounced among farmers with agricultural insurance and those primarily engaged in farming. Mechanistic analysis shows that operation scale partially mediates the relationship between organizational support and agricultural green production technology adoption, accounting for 7.76% of the total effect. Furthermore, social capital acts as a positive moderator, amplifying the impact of organizational support on the operation scale and, subsequently, on agricultural green production technology adoption. These results underscore the need to enhance organizational support measures, promote moderate-scale farming, and cultivate social capital as critical strategies for advancing green agricultural practices.
Numerical Analysis of Aerodynamic and Thermal Performance of Streamline Heat Pipe Heat Exchanger Assisted by Fins
Authors: Qi Weicheng , Lyu Yuanwei , Zeng Honggang , Zhang Jingyang , Wang Fenming
Published: February 2025

This study numerically explores the feasibility of a streamlined heat pipe heat exchanger in precooling technology in supersonic vehicles. Emphasis has been placed on the role of fins installed in the condensation section in affecting the aerodynamic and thermal characteristics of the streamline heat pipe heat exchanger. The results show that the installation of fins in the condensation section effectively improved the overall heat transfer capacity of the streamline heat pipe heat exchanger. The temperature drop with fins is up to 685 K, which is 20 K larger than the case without fins. Simultaneously, fins resulted in 6.4% and 25.4% increases in the pressure loss coefficient in the evaporation and condensation section compared to the case without fins. The aerodynamic and thermal characteristics are closely related to the mass flow rate of intake air and kerosene (RP-3). The pressure drop and temperature drop are positively related to the mass flow rate of RP-3. In contrast, as the qa increases, the heat exchange per qa decreases, and the temperature of the air outlet of the evaporation section increases correspondingly. In the evaporation section, as the qRP-3 increases, the temperature drop in the condensation section first increases and then remains unchanged, and its pressure loss coefficient decreases. The temperature drop in the intake air is positive and related to the qRP-3. The results obtained in this study are significant because they can provide technical support in the high performance of heat exchangers.
Exploration of Solar Power System Integration for Sustainable Air Transportation—A Case Study for Seaplane Air Taxi Operations
Authors: Liscouët-Hanke Susan , Mir Mohammad , Bashir Musavir
Published: February 2025

To reduce the environmental impact of airborne transportation, the aeronautic community investigates smaller aircraft with short-range operations (such as training aircraft, air taxis, or commuter aircraft) as technology incubators. This paper contributes to this effort by presenting an analysis framework and a detailed case study for integrating an auxiliary solar power system for air taxi operations. The solar power system conceptual design and analysis framework is improved to capture important effects for more realistic analysis for smaller aircraft, such as allowing the solar power system’s efficiency to be estimated as a function of aircraft mission parameters (temperature, speed, cloudiness) and providing a detailed view of the new system’s weight estimation considering potential physical integration scenarios. A detailed analysis of Harbour Air’s seaplane air taxi operations and the DHC-2 Beaver is performed using this enhanced design framework. The results show that the solar power system output exceeds the required secondary electrical power for 86% of the mission in one season; hence, it provides the potential to supplement a hybrid electric propulsion system. Secondly, the authors designed experiments to investigate the sensitivity of technology uncertainties for one critical mission. The results show that a small fuel burn reduction can be achieved with current technologies, with a promising trend of more savings with increasing system efficiency. Also, the results show that accumulated over a season’s operation, the CO2 emissions from the aircraft can be reduced. The findings indicate that integrating solar power systems can supplement traditional power sources and improve ground operations: specifically, solar energy could power a zero-emission and autonomous air-conditioning system while parked. Overall, integrating solar power into seaplane air taxi operations, even as a retrofit, presents a viable strategy for achieving more sustainable air transportation.