bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of handheld optical sensors and drone-acquired multispectral images for yield estimation
Authors:   Instituto Mexicano de Tecnología del Agua, Gordillo-Salinas Víctor Manuel , Villeda-Monsalvo Alondra ,   Grupo de Investigación & Evaluación Agrícola TECO S.A. de C.V, Arista-Cortes Juan ,   Instituto Mexicano de Tecnología del Agua, Flores-Velázquez Jorge ,   Colegio de Postgraduados
Published: September 2024

Introduction:Chlorophyll in wheat leaves is linked to grain yield, and measuring its reflectance allows predicting crop yield. Objective: To evaluate the potential of GreenSeeker (GS) and SPAD502+ sensors, and spectral images acquired with an infrared camera fitted on an unmanned aerial vehicle (UAV) to estimate grain yield in wheat. Methodology: Variable nitrogen concentrations were applied, and readings were taken with SPAD502+ and direct GS on wheat during the thickened sheath and heading phenological stages. Simultaneously, aerial images were captured with a multispectral camera to determine vegetation indices. Results: The comparison between measured and estimated yields with optical sensors shows that GS presented the best fit, with a coefficient of determination (R2) of 0.86 in thickened sheaths. The fit with the green normalized difference vegetation index (GNDVI) was better in heading (R2 = 0.89). Limitations of the study: Sensors with higher spectral resolution and earlier crop stages should be evaluated to estimate yield earlier. Originality: The study shows the potential of optical sensors to estimate yield, thereby overcoming the time and economic resource limitations entailed in conventional methods. Conclusions: GNDVI and GS are reliable, fast and non-destructive options to forecast wheat grain yield; however, UAVs allow scaling up crop monitoring and reducing the time to obtain field information.
Community entrepreneurship development (CED) as a strategy for poverty reduction and security in Nigeria
Authors: Poi, Godwin
Published: September 2024

Poverty and insecurity are pressing concerns in Nigeria, where a significant portion of the population live below the poverty line and face threats to their personal safety. This study investigated the potential of community entrepreneurship development as a strategy for reducing poverty and enhancing security in Nigeria. The study reviewed extant literature and analysed secondary data from reputable sources such as government reports, academic journals, and international organisations, to explore the relationship between community entrepreneurship development, poverty reduction, and security outcomes in Nigeria. The results indicate that existing initiatives that are aimed at developing community entrepreneurship can significantly contribute to poverty reduction in Nigeria, especially in rural regions where economic opportunities are limited. It found that entrepreneurial activities can increase household incomes, improve food security, and enhance access to basic services, thereby reducing poverty rates. Furthermore, the findings indicate that community entrepreneurship development can contribute to improved security outcomes by reducing youth unemployment, a key driver of social unrest and crime.
Keywords:  Community Entrepreneurship, Community Development, Poverty, Security.
University of the Third Age in A Limiting Social Exclusion of the Elderly: A Case Study in Poland
Authors: SOBOLEWSKA-PONIEDZIAŁEK Ewa , Niewiadomska Anna
Published: September 2024

The discourse on multidimensional consequences of the growing dynamics with regard to the population ageing process has continued unabated for several decades. Although it is often dominated by analyses pointing to the negative economic consequences of the growing proportion of elderly people, awareness of the inevitability of demographic change direction has brought a new perspective on meeting the needs of this social group. Research shows that elderly people often experience social exclusion, which can further exacerbate an often difficult situation due to the various types of limitations faced with age. In order to counteract exclusion as well as to activate and integrate seniors, the concept of establishing universities of the third age (U3A) has been introduced. This form of activity met with great interest and spread in a fairly short time, creating a platform for many initiatives. Nevertheless, the issue of the functioning of Universities of the Third Age as an entity offering various forms of support for the elderly is not a very common subject of research. Therefore, it is worth adding to the scope of knowledge on how these entities can reduce the scale of marginalization of seniors. The main aim of this paper is to describe the scope of third-age universities with particular emphasis on the functions they perform in the context of counteracting the social exclusion of seniors. In order to achieve this goal, an example of the functioning of these units in Poland was used, presenting key data showing the development of such institutions, the profile of participants, the area of activity and the main sources of funding. The research method used is desk research, while the data subject to analysis was taken from the Central Statistical Office (CSO) public statistics.
Bimekizumab (Bimzelx)
Authors: CADTH
Published: September 2024

Reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada’s federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses bimekizumab (Bimzelx), 160 mg/mL, solution for subcutaneous injection.
Indication: The treatment of adult patients with active psoriatic arthritis (PsA). Bimzelx can be used alone or in combination with a conventional nonbiologic disease-modifying antirheumatic drug (cDMARD) (e.g., methotrexate).
Consumption patterns of sugar-sweetened beverages among tertiary institution students in Abeokuta, Nigeria and their association with the risk of developing type 2 diabetes using FINDRISC
Authors: Akinbule Oluwafunke O. , Adenusi Sultan A. , Olurin Temitayo K.
Published: September 2024

Background: Increased consumption of Sugar-Sweetened Beverages (SSBs), with overweight and obesity have been associated with the risk of developing type-2 diabetes mellitus (T2DM). Aims: This study was aimed at assessing the pattern of consumption of SSBs and factors associated with the risk of developing T2DM within ten years among emerging adults in Abeokuta, (Nigeria). Methods: A cross-sectional survey of 350 students in public tertiary institutions in Abeokuta was undertaken using stratified random sampling. Data on SSBs consumption pattern and risk of developing T2DM was obtained using validated questionnaire. Height, weight and waist circumference (used to assess abdominal obesity (AO) were measured using standard procedures. Body mass index (BMI/BMI-for-age) was calculated. Fischer’s exact test and binary logistic regression were employed to test for associations among variables. Results: Most (62.9%) of the respondents were female and within the age-range of 20-24 years. Carbonated drinks were the most commonly consumed SSB (99.7%). Participants consuming carbonated drinks more than twice weekly had higher rate of overweight (27.3%) and obesity (12.0%). Consuming fruit drinks (OR = 15.2, 95% CI = 1.971, 117.400), malt drinks (OR = 3.2, 95% CI = 1.862, 5.571), and other beverages (OR = 2.9, 95% CI = 1.293, 6.899) more than twice weekly increased the odds of developing diabetes. Conclusion: The high prevalence of SSB consumption among the study population highlights the need for interventions to reduce consumption and mitigate associated health risks, including overweight, obesity, and T2DM.
A JORNADA DA BILIRRUBINA: ENTENDENDO E GERENCIANDO A ICTERÍCIA EM RECÉM-NASCIDOS
Authors: Silva Audrea Andressa Canever , Detoni Fernanda Rabello , Souza Luiza Cunha de , Souza Raycia
Published: September 2024

A icterícia neonatal é uma condição comum em recém-nascidos, caracterizada pelo acúmulo de bilirrubina no sangue, resultando em uma coloração amarelada da pele e mucosas. Essa condição pode ocorrer devido a diversas causas, sendo as mais frequentes a icterícia fisiológica, que surge devido à imaturidade hepática, e a icterícia patológica, que pode ser decorrente de condições como incompatibilidade sanguínea (ex: Rh ou ABO), infecções, distúrbios metabólicos ou hematológicos. Este artigo revisa os principais mecanismos subjacentes à icterícia neonatal, os métodos diagnósticos para sua avaliação e as estratégias de manejo recomendadas. A icterícia fisiológica geralmente se resolve espontaneamente sem intervenção médica, mas a icterícia patológica requer uma abordagem mais detalhada para tratar a causa subjacente e prevenir complicações, como o kernicterus. Os métodos diagnósticos incluem a medição dos níveis de bilirrubina sérica e a avaliação clínica do padrão de icterícia. O tratamento pode envolver fototerapia para reduzir os níveis de bilirrubina e, em casos mais graves, exsanguíneotransfusão. A compreensão abrangente das causas, diagnóstico e tratamento da icterícia neonatal é crucial para a gestão eficaz e a melhoria dos resultados clínicos nos recém-nascidos.
INCLUSÃO TECNOLÓGICA NA EDUCAÇÃO PROFISSIONAL INTEGRADA AO ENSINO MÉDIO EM RIO BRANCO: O USO DAS PLATAFORMAS MOODLE E GOOGLE MEET
Authors: Lima Adriana Alves de
Published: September 2024

Este estudo tem como objeto a implantação do Ensino Médio Integrado à Educação Profissional na área da saúde no Estado do Acre, especificamente no município de Rio Branco, através dos cursos de Enfermagem, Estética e Saúde Bucal ofertados pela Rede Pública Estadual de Educação. O objetivo central é investigar as razões pelas quais a implementação desse modelo educacional não foi concluída até o final de 2019, conforme previsto. A metodologia adotada combina revisão bibliográfica com pesquisa de campo realizada na Escola Técnica em Saúde Maria Moreira da Rocha, utilizando como corpus a experiência do ensino integrado na instituição. O estudo é de natureza qualitativa, exploratória, e baseia-se nas abordagens teóricas de Moura (2007), Rehem (2009) e Saviani (1987). Os resultados apontam que, para que a integração entre a educação profissional e a educação básica seja efetiva, é necessária mais do que uma decisão política formalizada por decreto; é imprescindível um trabalho pedagógico coletivo dentro das escolas, aliado à formação continuada dos docentes e à garantia de efetivação profissional. Além disso, identificou-se que a alta rotatividade de professores, a falta de financiamento adequado e a escassez de insumos para estágios supervisionados são barreiras que comprometem a qualidade da formação profissional integrada. Conclui-se que a efetiva integração entre educação básica e profissional depende de ações pedagógicas e estruturais que envolvam investimento contínuo na formação docente e no suporte material.
DE NOITES E BOLEROS: A POESIA DA CANÇÃO LATINO-AMERICANA E AS IMAGENS IDENTITÁRIAS NO IMAGINÁRIO SOCIAL
Authors: Lima Adriana Alves de
Published: September 2024

Este artigo realiza uma análise discursiva das canções latinas "Noche de Ronda," "La Barca," e "Bésame Mucho," interpretadas pelo cantor mexicano Luis Miguel Gallego Baster, com o objetivo de investigar as múltiplas representações identitárias da América Latina no imaginário social. A pesquisa busca entender como esses discursos poéticos, marcados por uma linguagem passional e melodramática, contribuíram para consolidar uma visão estereotipada da região no panorama cultural internacional, frequentemente retratada como uma terra de sujeitos homogêneos. A metodologia adotada baseia-se na Análise do Discurso, utilizando como fundamentação teórica os estudos de Canclini (1997), Bhabha (1998), Hall (2005), Santiago (2000), Todorov (1982), e Gomez-Peña (1997), que auxiliam na compreensão da pluralidade e fragmentação das identidades latino-americanas. O estudo conclui que as letras dessas canções revelam sujeitos pós-modernos, fragmentados e heterogêneos, questionando a ideia de uma América Latina singular e apontando para a complexidade cultural e identitária da região.
FIBRILAÇÃO ATRIAL: UMA REVISÃO DA LITERATURA FOCADA NOS MECANISMOS PREDISPONENTES
Authors: Simões Luiz Alberto Ribeiro , Gandra Sara Amorim , Generoso Tatiane Otoni Silva , Colares Thamires Aparecida Fernandes
Published: September 2024

A fibrilação atrial (FA) é considerada a arritmia mais frequente a ser tratada na prática clínica e está associada a um risco potencial aumentado de óbito, acidente vascular cerebral e embolia periférica. O estudo Global Burden of Disease mostra que a prevalência estimada de FA é de até 33,5 milhões de pacientes. A identificação de fatores de risco modificáveis ​​para o surgimento da FA e medidas preventivas adequadas podem desempenhar um papel significativo na melhoria da saúde dos pacientes e na redução dos gastos do sistema de assistência médica. Vários mecanismos, incluindo a remodelação elétrica e estrutural do tecido atrial, foram propostos para contribuir para o surgimento de FA. Este artigo de revisão da literatura discute os fatores predisponentes na FA, como estilo de vida sedentário e hábitos alimentares, considerando seus diferentes mecanismos patogênicos.
INSUFICIÊNCIA DA VALVA AÓRTICA: ASPECTOS CLÍNICOS, DIAGNÓSTICOS E TRATAMENTO
Authors: Ardisson Giulia Machado Caldeira , Souza Thiago Ribeiro de
Published: September 2024

Esta revisão narrativa de literatura reuniu artigos publicados preferencialmente em inglês, espanhol, francês e português nos últimos cinco anos na base de dados PUBMED com o objetivo de revisar a insuficiência da valva aórtica, abordando sua etiologia, fisiopatologia, diagnóstico e manifestações clínicas. A insuficiência da válvula aórtica (IVA), ou regurgitação aórtica, ocorre quando a válvula aórtica não fecha durante a diástole, permitindo o refluxo de sangue da aorta para o ventrículo esquerdo. Isso resulta em sobrecarga volumétrica, dilatação e hipertrofia do ventrículo esquerdo, podendo causar disfunção ventricular e insuficiência cardíaca. As principais causas de IVA incluem endocardite infecciosa, dissecção aórtica, degeneração valvar, febre reumática e aneurismas da aorta ascendente. A condição pode ser assintomática por anos, com sintomas como dispneia, fadiga e angina surgindo em estágios mais avançados. O diagnóstico é feito principalmente por ecocardiografia, que avalia a válvula e a função ventricular. A progressão da doença é influenciada por fatores como idade, hipertensão e doenças do tecido conjuntivo, e o prognóstico depende da gravidade e da disfunção ventricular associada.
TERAPIAS ANTIOXIDANTES NO MANEJO DA DOENÇA DE ALZHEIMER: UMA REVISÃO INTEGRATIVA
Authors: Ferreira Tainan Gomes , Sales Elvis Bezerra de Souza , Rios César Henrique de Miranda Lana , Campigotto Roberto Spadoni
Published: September 2024

A Doença de Alzheimer (DA) é uma condição neurodegenerativa complexa caracterizada por deterioração cognitiva progressiva e acúmulo de placas amiloides e emaranhados neurofibrilares. As terapias antioxidantes têm sido estudadas como uma abordagem potencial para mitigar o estresse oxidativo associado à patogênese da DA. Esta revisão integrativa visa avaliar a eficácia das principais terapias antioxidantes no manejo da DA, incluindo vitamina E, coenzima Q10, polifenóis, curcumina e ácido lipoico. Através da análise de ensaios clínicos, estudos pré-clínicos e revisões sistemáticas, foram identificados efeitos diversos dessas terapias, com alguns mostrando potencial neuroprotetor e outros apresentando benefícios clínicos limitados. Os resultados sugerem que, embora existam indícios de eficácia, os efeitos terapêuticos das intervenções antioxidantes são variáveis e dependem de fatores como a formulação, a dosagem e a fase da doença. A combinação de antioxidantes com outras modalidades terapêuticas pode oferecer uma abordagem mais abrangente no tratamento da DA. Futuras pesquisas são necessárias para padronizar protocolos de tratamento, explorar mecanismos subjacentes e avaliar a eficácia das terapias antioxidantes em diferentes subgrupos de pacientes.
EFICÁCIA DE PROTOCOLOS DE CUIDADO PALIATIVO EM PACIENTES COM DOENÇAS CRÔNICAS: UMA REVISÃO INTEGRATIVA
Authors: Carminate Camila Baquieti , Pinheiro Mariana Torres , Vieira Brenda Gomes , Veloso João Henrique Teixeira
Published: September 2024

O cuidado paliativo tem se consolidado como uma abordagem essencial para melhorar a qualidade de vida de pacientes com doenças crônicas, focando na gestão de sintomas e suporte integral ao paciente e à família. Esta revisão integrativa avalia a eficácia de diversos protocolos de cuidado paliativo na gestão de doenças crônicas, com ênfase em sua capacidade de proporcionar alívio dos sintomas, melhorar a qualidade de vida e atender às necessidades psicossociais dos pacientes. A metodologia incluiu uma análise sistemática de estudos publicados em bases de dados científicas como PubMed, Scopus e Web of Science, abrangendo a literatura de 2010 a 2023. Os critérios de inclusão abrangeram estudos que investigaram a eficácia de intervenções paliativas em pacientes com doenças crônicas, enquanto estudos focados exclusivamente em cuidados paliativos oncológicos foram excluídos. Os resultados indicam que os protocolos de cuidado paliativo são eficazes na redução dos sintomas, na melhora da qualidade de vida e na satisfação dos pacientes. Contudo, a variabilidade na implementação e nos desfechos observados sugere a necessidade de mais pesquisas para padronizar e otimizar esses protocolos. A revisão conclui que, apesar dos avanços significativos, há uma necessidade contínua de desenvolvimento e avaliação de protocolos para atender melhor às complexas necessidades dos pacientes com doenças crônicas.
Estrategias para mejorar la gestión de competencias laborales en las PYMES
Authors: Cevallos Gorozabel Elizabeth Mercedes
Published: September 2024

El propósito de este artículo es desarrollar estrategias para mejorar la gestión de competencias laborales en las pequeñas y medianas empresas (pymes) del cantón Esmeraldas. Se proponen dos estrategias principales: un plan de aprendizaje y desarrollo que ofrece educación y preparación a los colaboradores a través de programas de formación en línea, y la rotación de puestos de trabajo, que permite adquirir nuevas habilidades desde diferentes roles, identificando áreas de mejora y necesidades de desarrollo para ascender a posiciones de mayor responsabilidad. El enfoque metodológico utilizado es descriptivo, con un diseño de campo no experimental. La muestra consistió en treinta empleados administrativos de empresas constructoras  del cantón Esmeraldas. La recopilación de datos se realizó mediante un cuestionario de 10 ítems con respuestas tipo escala Likert. Los datos fueron analizados estadísticamente utilizando frecuencias absolutas y relativas, así como medidas de tendencia central y desviación estándar, presentados en tablas. Los resultados sugieren que las estrategias implementadas están diseñadas para promover el desarrollo de competencias en los empleados, alineándose con las necesidades y procesos del entorno para mejorar la competitividad de las organizaciones.
Aportes Académicos: Investigaciones Penales desde Esmeraldas
Authors: Cevallos Gorozabel Elizabeth Mercedes , Castillo Cevallos Carolina Elizabeth
Published: September 2024

El artículo presenta una colección de trabajos realizados por un grupo de alumnos de la Maestría en Derecho Penal, que forman parte de la serie "Aportes académicos: Investigaciones Penales desde Esmeraldas". Estos ensayos abordan temas de actualidad en el campo del derecho penal y se presentan como contribuciones a la sociedad esmeraldeña. Los participantes exploran diversas temáticas, desde una perspectiva histórica hasta cuestiones contemporáneas, destacando la evolución del pensamiento jurídico penal y su impacto en la sociedad. Se enfatiza la importancia de comprender el delito como una construcción cultural y jurídica que se ha adaptado a lo largo del tiempo. Además, se resalta el esfuerzo y dedicación de los alumnos, así como el reconocimiento recibido por parte de la comunidad académica. El objetivo principal de estos trabajos es contribuir a una mejor comprensión y solución de los problemas actuales en el ámbito del derecho penal, mientras se promueve la continuación del proyecto para completar la colección sobre cada una de las áreas del derecho. Esta serie de investigaciones representa un aporte significativo para la comunidad de Esmeraldas, proporcionando herramientas teóricas y prácticas que pueden influir positivamente en la formulación de políticas y en la administración de justicia penal. La continuidad del proyecto promete enriquecer el debate académico y profesional, fomentando una comprensión más profunda del derecho penal y su aplicación en la sociedad actual.
Nacimiento, mortalidad y sobrevivencia de la empresa mexicana
Authors: Ruiz Ramírez Héctor
Published: September 2024

El presente documento tiene como objetivo hacer una descripción de la dinámica demográfica de la empresa mexicana, es decir, su nacimiento, muerte y supervivencia de 2008 a 2021, observando este comportamiento en la micro, pequeña y mediana empresas (MiPymes) mismas que se vieron afectadas en su producción y empleo por la pandemia ocasionada por el COVID-19. Se inicia con la revisión de la literatura relacionada con las MiPymes y la demografía empresarial y posteriormente se recopilaron estadísticas mexicanas producidas por el Instituto Nacional de Estadística y Geografía (INEGI) que han servido de base para realizar un análisis descriptivo y numérico gráfico sobre la muerte, nacimiento y sobrevivencia de la empresa por tamaño, el impacto que hubo en ellas por la pandemia y su efecto en el empleo.
Diseño de una intervención familiar a partir del modelo sistémico
Authors: Galán Rello Daniel
Published: September 2024

En el campo de la acción social, la intervención con familias en riesgo de exclusión social es prioritaria. La evaluación del riesgo del sistema familiar busca identificar elementos que amenacen el bienestar y funcionamiento familiar, detectando factores de riesgo y, por otro lado, factores protectores que ayudan a mitigar estos riesgos y promover el bienestar familiar. El modelo de intervención sistémico considera a la familia como un sistema complejo de subsistemas interrelacionados. Adoptando una perspectiva holística, se analizan tanto los problemas familiares como su contexto social más amplio para desarrollar estrategias efectivas y centradas en fortalecer a la familia. Estas estrategias son adaptadas a las necesidades específicas de cada familia para maximizar su efectividad.
La familia en constante transformación: un análisis desde la perspectiva actual
Authors: Rodríguez Valladolid Natalia , Galán Rello Daniel
Published: September 2024

El concepto de familia ha evolucionado significativamente, dando lugar a estructuras más diversas y dinámicas. Los cambios sociales, demográficos y culturales han generado nuevos desafíos para las familias, como la conciliación entre la vida personal, laboral y familiar, el cuidado de los mayores y la solidaridad intergeneracional. La crisis de los cuidados, agravada por la desigualdad de género en las tareas domésticas, ha puesto de manifiesto la necesidad de implementar políticas públicas que promuevan la corresponsabilidad y el apoyo a las familias. Es fundamental replantear los roles entre hombres y mujeres y redistribuir las responsabilidades de cuidado para lograr una mayor equidad y bienestar social. La familia del futuro requiere de un enfoque integral que combine políticas públicas, cambios culturales y una mayor participación de todos los miembros de la sociedad.
RISK STRATIFICATION OF POSTOPERATIVE ASYMPTOMATIC ST-SEGMENT DEPRESSION IN PATIENTS WITH ACUTE CHOLECYSTITIS
Authors:   Belarusian State Medical University, D. S. Herasimionak , S. I. Kuznetsova ,   Belarusian State Medical University, N. P. Mitkovskaya ,   Belarusian State Medical University
Published: September 2024

Background. Despite the successes in the prevention and treatment of diseases of the circulatory system, mortality from ischemic heart disease (IHD) among the population of the Republic of Belarus occupies a leading position. Late seeking of medical care by patients with coronary artery disease may be due to the peculiarities of the course of the disease, asymptomatic episodes of myocardial ischemia, which do not allow timely suspicion and prevention of an impending coronary catastrophe without conducting instrumental studies and assessing cardiovascular risk. Acute surgical pathology of the abdominal organs can serve as a stress trigger that will worsen the course of asymptomatic coronary atherosclerosis and lead to the manifestation of an ischemic event. Aim. To assess the incidence and develop a prognostic model for the occurrence of ST segment depression on the resting electrocardiogram (ECG) in patients after cholecystectomy in the early postoperative period. Material and methods. The study included patients with moderate, high and very high risk of cardiovascular complications according to the recommendations of the European Society of Cardiology [1], who had indications for urgent cholecystectomy. Ischemic depression of the ST segment was considered to be an oblique or horizontal depression with a depth of 0.05 mV or more in the standard leads and 0.1 mV or more in the precordial leads, measured at a point 60-80 ms from the point of transition of the S wave to the ST segment. Results and discussion. In patients who underwent cholecystectomy but did not use cardioprotective therapy, ST segment depression on the ECG was more common on the 4th day after surgery. The prevalence of ischemic ST segment depression was higher in both standard and precordial leads. An increase in the incidence of new episodes of myocardial ischemia by day 4 in patients after cholecystectomy without concomitant cardioprotective therapy was also revealed. A model was developed to estimate the likelihood of episodes of ST segment depression after emergency cholecystectomy in the early postoperative period. Conclusion. In patients after cholecystectomy in the early postoperative period, episodes of ST segment depression were recorded on the resting ECG. The frequency of asymptomatic episodes of ischemia was higher in the group of patients who underwent cholecystectomy, where no additional cardioprotective therapy was prescribed.
A CLINICAL CASE OF SUCCESSFUL HEART CONDUCTION SYSTEM PACING AFTER RADIOFREQUENCY ABLATION OF MAHEIM TRACT IN A PATIENT WITH ATRIOVENTRICULAR BLOCK AND ARRHYTHMOGENIC CARDIOMYOPATHY
Authors: V. Kadochkin , D. Pilant , K. Drozdovski , E. Rudich
Published: September 2024

The article presents a clinical case of heart conduction system pacing (left branch of bundle (LBB)area) after radiofrequency ablation (RFA) of an accessory pathway with rare localization and features (Maheim tract) in a patient with atrioventricular block (AV-block) and arrhythmogenic cardiomyopathy. We have also covered the issues of diagnosis and management of the ventricular pre-excitation syndrome determined by Maheim tract and prospects of the new method of physiological electrocardiostimulation, i.e. of LBB areapacing.
REVISED EUROPEAN TASK FORCE CLINICAL RECOMMENDATIONS FOR DIAGNOSIS OF ARRHYTHMOGENIC CARDIOMYOPATHY (2023)
Authors: S. Komissarova , N. Rineiska , A. Efimova , N. Chakova
Published: September 2024

In order to improve the diagnosis of arrhythmogenic cardiomyopathy (ACM) in 2023, leading European experts validated new recommendations and a consensus report with augmented criteria for diagnosis of ACM (based on modified ITF criteria 2010 and Padua criteria 2020). The article highlights the crucial aspects of diagnosis and practical experience of novel criteria for the recognition of various phenotypes of ACM.
WHAT IS THE QUESTION. WHAT TO DO ABOUT OXIDATIVE STRESS OR WHAT IS THE CAUSE OF PREMATURE AGING OR WHETHER YOU NEED TO TAKE THE ANTIOXIDANTS.
Authors:   Belarusian State Medical University, Vadim. G. Tsapaev
Published: September 2024

The original meaning of the word medicine is to know, understand, comprehend, distinguish. It is the comprehension and understanding of the processes occurring in the patient’s body that is the basis for recognizing the disease and choosing treatment for the disease. Modern medical science has two forms: medicine itself as the treatment of a sick person and healthcare as a complex of public organizational and managerial measures aimed at maintaining public health. Given the undoubted synergy of these two humanitarian foundations, it should be recognized that the dominance of social forms of medicine has an inhibitory effect on individual medicine. At the same time, individual health care is a priority for the individual. Modern scientific opinions are based on stereotypes derived from statistical conclusions, and not on an understanding of the pathogenetic mechanisms of diseases and their healing. This is largely facilitated by the uncontrolled circulation of unprofessional pseudoscientific information on the Internet and the media. As a result, ideas about the essence of diseases and methods of therapy are formed in the form of primitive clichés of the “good and bad” type. Such stereotypes include views on oxidative processes in the body and especially on antioxidants: “Reactive oxygen species are very bad, antioxidants are good.” In this article we would like to present a scientific point of view on this issue, drawing on the achievements of physiology and biochemistry, especially since this section of science is intensively developing at the present time.
Nova arheološka saznanja s prostora Prigorja
Authors: Mavrović Mokos Janja , Ovčarić Franka , Šejić Laura
Published: September 2024

U članku ćemo predstaviti nove rezultate arheoloških istraživanjai terenskih pregleda obavljenih u sklopu projekta „Transfernopodručje od Sutle preko gornjeg toka rijeke Save tijekombrončanog i željeznog doba – TRANS RIVERS“ financiranogaod strane Hrvatske zaklade za znanost na prostoru Prigorja.Spomenut ćemo i sva dosadašnja istraživanja bilo zaštitna ilisustavna, kao i sve slučajne nalaze predane u razne muzeje izvremena prapovijesti na spomenutome području. Cilj nam jepokazati kako je taj slabo istraženi prostor bio vrlo važan u prapovijesnimvezama i komunikacijama zbog blizine Save koja jebila jedna od žila kucavica u protoku roba, ideja i sirovina. Predstavitćemo stratigrafski kontekst i nalaze iz prve sustavnoistražene kasnohalštatske kuće iz Svetoga Križa te iz drugogadjelomično istraženoga objekta koji se naslanja na prvi. Ta sustavnaarheološka istraživanja provode se u Svetome Križu od 2019., a u radu ćemo obuhvatiti sve podatke završno s istraživanjimaprovedenima tijekom 2022. Iste je godine istražen i jedankasnobrončanodobni objekt na novootkrivenome lokalitetuGračec. Lokalitet je otkriven u sklopu terenskoga pregleda tijekomprve godine provedbe projekta. Predstavit ćemo smještajnaselja Gračec, stratigrafske odnose unutar istraženoga objektate nalaze koji upućuju na to da je riječ o lokalitetu iz vremenamlađe faze kulture polja sa žarama. To je prvi cjelovito istraženistambeni objekt iz spomenutoga razdoblja sa širega prostora,što s pouzdanom stratigrafijom, nalazima iz zatvorenoga kontekstai radiokarbonskim datumima tvori temelj za nove spoznajes kraja kasnoga brončanog doba.
New epigraphic confirmation of governor’s strator from Salona
Authors: Matijević Ivan
Published: September 2024

During archaeological excavations of the city walls south ofthe cemeterial basilica at Kapljuč in Salona in 2021, a fragmentof a stele was discovered. The stele was erected during theLate Principate period in this part of the so-called Northernnecropolis by Aurelius Candidianus. He likely commemorated hiswife, whose name has not been preserved. Candidianus servedas a strator in the governor’s officium in Salona. Although he didnot specify his unit affiliation, it can be assumed to have beenone of the five auxiliary units stationed in Dalmatia at that time.
Fars, Kürt ve Arap Dillerindeki Türkler ve Türkiye Türkçesinde Arap, Acem ve Kürtler
Authors: Akbalaban Cengiz
Published: September 2024

For nearly a thousand years, Turks, Persians, Arabs and Kurds have lived and continue to live together with each other. The idioms, proverbs, words and expressions they have produced mutually about each other have been brought together in this study. Mixed methods were used in the study. Scans were made with both document analysis and also compilation was carried out through face-to-face interviews. As a result of the study, 147 items were identified in Arabic, 213 in Persian and 88 in Sorani Kurdish regarding Turks. These words were classified according to both their field of use and meaning. The data obtained as a result of the classifications were shown with graphs and their comments were made. As a result, it was revealed that the most words were in Persian, Arabic and Sorani Kurdish, respectively. As a result of the study, it was determined that there were 72 items related to Arabs, 33 to Persians/Iranians and 36 to Kurds in Turkish. As in other languages, the words in Turkiye Turkish were classified and commented in terms of meaning and theme. Keywords: Arabian langugae, Turkey Turkish, image study, Persian language, Kurdish langugae.
DINÂMICA DOS PORTOS GRANELEIROS DA SOJA NA AMAZÔNIA BRASILEIRA: O CASO DE SANTARÉM E ITAITUBA, PARÁ
Authors: Benassuly Barros Márcio Júnior
Published: September 2024

A presente pesquisa tem como objetivo analisar a dinâmica da instalação dos portos graneleiros da soja na Amazônia legal, tendo como ênfase os municípios de Santarém e Itaituba, Pará, Brasil. A metodologia aplicada está amparada em uma pesquisa quantitativa e qualitativa, o que consistiu no levantamento documental, bibliográfico, utilizando a técnica de trabalho de campo com entrevistas de moradores locais, trata-se de um estudo de caso. Os principais resultados indicam que, com a instalação do Terminal de Graneis Sólidos da Cargill em Santarém (2003) e de cinco Estações de Transbordo de Cargas (ETC) em Miritituba/Itaituba, a partir de 2014, houve uma série de mudanças de natureza sociais – econômicas – territoriais, afetando o cotidiano de populações em Santarém e Itaituba
PRESSÕES EM TERRAS INDÍGENAS PELA ATIVIDADE MINERÁRIA NA AMAZÔNIA BRASILEIRA
Authors: Gaspar Aquino Ronaldo Darlan , Moraes Ribeiro Mônica , Pontes Altem Nascimento
Published: September 2024

A Amazônia é conhecida pela sua complexidade de ecossistemas, riquezas minerais e território de povos indígenas, onde ocorrem diversos conflitos socioambientais. O objetivo do estudo foi analisar as pressões em terras indígenas causadas pela atividade minerária localizadas no estado do Pará. Os dados foram adquiridos em base de dados de órgãos oficiais brasileiros. Para a análise e tratamento dos dados foram utilizadas a álgebra de mapas e estatística descritiva para assim gerar o Índice de Pressão Mineral (IPM). Os resultados apontam que 90% das terras indígenas, são regularizadas, as maiores pressões são causadas pela atividade garimpeira e pela exploração do ouro. Cerca de 50% da extensão total das terras indígenas estudadas foi classificada com IPM Alto e Muito Alto. Os dados permitiram evidenciar que as terras indígenas mais vulneráveis para a atividade de mineração são a Menkragnoti, Baú, Apyterewa, Arara, Xikrin do Rio Catete, Terra Sai-Cinza, Parque do Tumucumaque, Riu Paru D’este, Trombetas/Mapuera e Manhudá/Mapuera. Assim, este estudo pretende fomentar a ação para novas pesquisas sobre essa temática, bem como apoiar ações e estratégias de instituições diversas que lutam pela sustentabilidade da Amazônia.
Uncovering anti-inflammatory potential of Lantana camara Linn: Network pharmacology and in vitro studies
Authors: Khairan Khairan , Maulydia Nur B. , Faddillah Vira , Tallei Trina E. , Fauzi Fazlin M. , Idroes Rinaldi
Published: September 2024

Lantana camara Linn contains a diverse array of metabolites that exhibit therapeutic potential. The aim of this study was to evaluate the potential of L. camara leaves, which were collected at the Ie-Seu'um geothermal area in Aceh, Indonesia, as an anti-inflammatory through network pharmacology and in vitro analysis. The ethanolic extract derived from L. camara underwent identification utilizing gas chromatography-mass spectrometry (GC-MS) to verify chemical constituents for drug-likeness properties. The evaluation of anti-inflammatory activity included network pharmacology and a series of in vitro investigations using two methods: protein inhibition and albumin denaturation assays. The findings revealed that the extract contained a domination of terpenoids and fatty acids class, which met the evaluation criteria of drug-likeness. Network pharmacology analysis identified the top five key proteins (peroxisome proliferator-activated receptor gamma, prostaglandin G/H synthase 2, epidermal growth factor receptor, hypoxia-inducible factor 1-alpha, and tyrosine protein kinase-Janus kinase 2) involved in inflammation-related protein-protein interactions. Gene ontology enrichment highlighted the predominance of inflammatory responses in biological processes (BP), cytoplasm in cellular components (CC), and oxidoreductase activity in molecular functions (MF). In vitro analysis showed that the extract inhibited protein activity and protein denaturation with inhibitory concentration (IC50) values of 202.27 and 223.85 ppm, respectively. Additionally, the extract had antioxidant activity with DPPH- and ABTS-scavenging IC50 values of 140 ppm and 163 ppm, respectively. Toxicological assessment by brine shrimp lethality assay (BSLA), yielding a lethal concentration (LC50) value of 574 ppm (essentially non-toxic) and its prediction via ProTox 3.0 that indicated non-active in hepatotoxicity, carcinogenicity, immunotoxicity, mutagenicity, and cytotoxicity. These results suggested that L. camara holds noteworthy effectiveness as a potential candidate for complementary medicine in the realm of inflammatory agents, warranting further investigation in clinical settings.
Predictores de sobrepeso y obesidad en conductores de taxi
Authors: Yambay Bautista Xavier , Aguirre Quezada María Alejandra , Pogyo Morocho Gloria Luzmila , Godoy Durán Elvia Narcisa
Published: September 2024

Introducción: Los conductores de taxi están propensos a una serie de factores de riesgo asociados a múltiples enfermedades, producto del sometimiento a estilos de vida no saludables. Objetivo: Estimar factores predictores del sobrepeso y obesidad en conductores de taxi, según variables socioeconómicas y dimensiones del estilo de vida. Metodología: Estudio cuantitativo, observacional, transversal, explicativo, llevado a cabo en un universo de 131 taxistas hombres, que trabajan en la ciudad de Azogues-Ecuador, aplicando la Escala del Estilo de Vida junto con la medición del peso y la talla de los participantes para obtener el índice de masa corporal. El análisis estadístico recurrió a métodos univariados (frecuencias, medidas de tendencia y dispersión) y multivariados (regresión logística binomial). Resultados: participantes de 35 a 42 años (45.8%), casados (90.84%), conducen más de 8 horas diarias (72.5%), con sobrepeso u obesidad (83.2%), llevan un estilo de vida no saludable global del 86.3%. La regresión logística mostró buen ajuste del modelo para las 3 variables incluidas: alimentación (OR = 1.53), apoyo interpersonal (OR = 0.454) y horas de conducción diarias (OR = 4.078). Discusión: Ser conductor de taxi es una actividad de riesgo para la salud que puede generar sobrepeso u obesidad, condiciones que pueden ser predichas por factores del estilo de vida y por condiciones laborales propias de esta actividad.
Knowledge and Practice of Mothers on Child Feeding Practices and Child Survival Strategies in Ibadan
Authors: Muyide Abimbola Magret , Sanusi Rasaki Ajani
Published: September 2024

Background and Objective: In spite of the recognition of the impact of optimal Infant and Young Child Feeding (IYCF) practices and Child Survival Strategies (CSS) for child health, Nigeria still remains one of the five countries that account for about 50% of under-five mortality in the world. This study was therefore conducted to assess the knowledge and practice of mothers on child feeding practices and child survival strategies in Ibadan.
Method: This descriptive cross-sectional study was done using a structured interviewer administered questionnaire to obtain information from 960 mothers of under-five children recruited from three Local Government Areas of Ibadan. Information was collected on mother’s socio-demographic characteristics, knowledge and practice of breastfeeding, complementary feeding, growth monitoring, oral rehydration therapy, immunization, food fortification, female education and vitamin A supplementation. Data analysis was done using SPSS version 21.
Result: Majority of the mothers got information regarding child nutrition and care from hospitals (85.9%). 44.5% of respondents practiced exclusive breast feeding. Only 51.5% of mothers practiced the recommended age of complementary food introduction at 6 months. Of all respondents, 74.5% had an average knowledge, 19.5% had good knowledge and only 6.0% poor knowledge of IYCF while 39.7% had poor practice and 60.3% had good practice of IYCF. For CSS, 71.4% had average knowledge, 10.4% had good knowledge and 18.2% poor knowledge while 10.2% had poor practice and 89.8% had good practice of CSS.
Conclusion: Knowledge of IYCF was higher than practice while level of practice of CSS was higher than its knowledge. Only education and source of information had a statistical significance with both IYCF and CSS. Although respondents demonstrated adequate practice of most of the components of CSS, there were gaps in knowledge, which was the direct opposite for IYCF. Also, the study reaffirms the importance of education and source of information in the knowledge and practice of IYCF and CSS.

Key words: Child survival, Child Feeding, Mothers, Knowledge, Practice
The Role of Tyrosine Kinases in Cancer: Signal Transduction Mechanisms and Therapeutic Targets
Authors: Rajeswari Aruna , Bhavani Balaprakash
Published: September 2024

Tyrosine kinases are key mediators in cellular signaling, governing essential processes such as growth, differentiation, metabolism, and apoptosis. In cancer, these kinases often become dysregulated due to mutations, overexpression, or autocrine-paracrine signaling, leading to uncontrolled cell proliferation and tumor development. Receptor tyrosine kinases (RTKs), a prominent subset, are frequently implicated in cancer, with many tumors exhibiting dependency on aberrant RTK signaling. This dependency has made RTKs a major focus for targeted cancer therapies, particularly through the development of small molecule tyrosine kinase inhibitors (TKIs). Despite the initial success of these inhibitors in clinical settings, the emergence of resistance remains a significant hurdle, often leading to relapse. Advances in technology are now facilitating the identification of novel RTK inhibitors, aiming to overcome resistance and improve therapeutic outcomes. This abstract highlight the importance of understanding the signal transduction mechanisms of tyrosine kinases and emphasizes their potential as therapeutic targets in the ongoing battle against cancer.

Key words: Tyrosine kinase, Cancer, signaling, Inhibitor, drugs
Exploring the Relationship between Parenting Stress, Resilience, and Self-Efficacy of First Aid for Home Accidents in Mothers with 0-4-Year-Old Children
Authors: Özkan Sevil , Bülbül Şahan
Published: September 2024

Objective: To determine the relationship between parenting stress, resilience, and self-efficacy of first aid for home accidents in mothers with 0-4-year-old children.
Materials and Methods: The study population comprised mothers in Turkey with children between 0 and 4 years old. The effect size was calculated based on existing literature, resulting in a value of 0.31 for Cohen's d. The G*Power 3.1.9.7 program was used to estimate the sample size, which was determined to be 66 individuals. A 20% increase was added to allow for people dropping out, making a final sample size of 80. The data were collected between March and June 2024 using the Information Form, Parenting Stress Scale (PSS), The Brief Resilience Scale (BRS), and the Self-Efficacy of First Aid Scale for Home Accidents (SEFASHA). The data were analysed using the SPSS 22.0 program, employing descriptive statistics and parametric or non-parametric tests for comparative data.
Findings: The study found that the average PSS score was influenced by factors such as age, place of residence, health status, education level, and history of accidents or injuries during the mother's childhood at home (p<0.05). Educational status and education life as a source of information about home accidents-first aid also affected the average SEFASHA score (p<0.05). The correlation between the average PSS and SEFASHA scores was positive and significant (r=0.030, p<0.05).
Conclusion: The study's findings determined that different variables affected mothers' PSS and SEFASHA mean scores and that there was a relationship between PSS and SEFASHA. In this context, the findings obtained on the subject are of great importance for the field of study and also emphasize the need for further research.

Key words: Mothers with 0-4-year-old, Parenting stress, Resilience, Self-efficacy of first aid for home accidents
Exploring Leadership Development Amongst Students Engaged in Residence Hall Council
Authors:   University of Maryland, College Park, Pierre Darren , Dunn Allison ,   Texas A&M University
Published: September 2024

Students learn how to be a leader and how to develop their leadership capacity as they participate in shared experiences or learning communities, many of which are facilitated by student affairs professionals through campus activities programs. For large numbers of college students, their first learning community, and subsequent path to future campus involvement, is their residential community. This qualitative study explored how participating in a residence hall council impacted students’ conceptualization of leadership and their individual leadership development. Two overarching themes emerged. First, students do in fact build leadership capacity, motivation, and leadership efficacy from participating in collaborative, learning community environments, such as a hall council. Second, the role and behaviors of the learning community advisor matter, providing practical considerations for all student affairs practitioners.
Evaluation of the Effect of Fuel Subsidy Removal on Academic Staff Productivity in Tertiary Institutions in Rivers State
Authors: N. W. Uchechi, , S. W. Ebere, , K. O. Sheila,
Published: September 2024

The study evaluated the effect of fuel subsidy removal on academic staff productivity in tertiary institutions in Rivers State. Three research questions and three hypotheses guided the study. This study adopted the descriptive survey design. The population of the study consisted of 3,154 academic staff from the three Universities in Rivers State. The sample size for this study was 340 respondents. The instrument used for data collection was a questionnaire titled: “Effect of Fuel Subsidy Removal on Academic Staff Job Productivity Questionnaire (EFSRASJPQ)”. Pearson’s Product Moment Correlation Coefficient method established the yielded reliability index of 0.89. Mean and standard deviation were used to answer the research questions while ANOVA was used to test hypotheses at a 0.05 level of significance. The study revealed that the removal of fuel subsidy affects the commuting costs of academic staff, demotivates academic staff and affects staff punctuality in Rivers State University, University of Port Harcourt and Ignatius Ajuru University of Education Nigeria. The study recommended that University managements should establish a transport support system or give allowances to academic staff to offset the increased commuting expenses.