bluuebunny/crossref_metadata_2025 huggingface dataset:
Ramadan fasting model exerts hepatoprotective, anti-obesity, and anti-hyperlipidemic effects in an experimentally-induced nonalcoholic fatty liver in rats
Authors: Alasmari Abeer A. , Al-Khalifah Abdulrahman S. , BaHammam Ahmed S. , Alshiban Noura M. S. , Almnaizel Ahmad T. , Alodah Hesham S. , Alhussain Maha H.
Published: August 2023

Background:

The epidemic of nonalcoholic fatty liver disease (NAFLD) and its metabolic effects present a serious public health concern. We hypothesized that the Ramadan fasting model (RFM), which involves fasting from dawn to dusk for a month, could provide potential therapeutic benefits and mitigate NAFLD. Accordingly, we aimed to validate this hypothesis using obese male rats.

Methods:

Rats were split into two groups (n = 24 per group), and they were given either a standard (S) or high-fat diet (HFD) for 12 weeks. During the last four weeks of the study period, both S- and HFD-fed rats were subdivided into eight groups to assess the effect of RFM with/without training (T) or glucose administration (G) on the lipid profile, liver enzymes, and liver structure (n = 6/group).

Results:

The HFD+RFM group exhibited a significantly lower final body weight than that in the HFDC group. Serum cholesterol, low-density lipoprotein, and triglyceride levels were significantly lower in the HFD+RFM, HFD+RFM+T, and HFD+RFM+G groups than those in the HFDC group. Compared with the HFDC group, all groups had improved serum high-density lipoprotein levels. Furthermore, HFD groups subjected to RFM had reduced serum levels of aspartate transaminase and alanine transaminase compared with those of the HFD-fed group. Moreover, the liver histology improved in rats subjected to RFM compared with that of HFD-fed rats, which exhibited macro- and micro-fat droplet accumulation.

Conclusion:

RFM can induce positive metabolic changes and improve alterations associated with NAFLD, including weight gain, lipid profile, liver enzymes, and hepatic steatosis.
Development and application of hepatocellular carcinoma risk prediction model based on clinical characteristics and liver related indexes
Authors: Liu Zhi-Jie , Xu Yue , Wang Wen-Xuan , Guo Bin , Zhang Guo-Yuan , Luo Guang-Cheng , Wang Qiang
Published: August 2023

Colitis-associated colorectal cancer (CAC) is defined as a specific cluster of colorectal cancers that develop as a result of prolonged colitis in patients with inflammatory bowel disease (IBD). Patients with IBD, including ulcerative colitis and Crohn’s disease, are known to have an increased risk of developing CAC. Although the incidence of CAC has significantly decreased over the past few decades, individuals with CAC have increased mortality compared to individuals with sporadic colorectal cancer, and the incidence of CAC increases with duration. Chronic inflammation is generally recognized as a major contributor to the pathogenesis of CAC. CAC has been shown to progress from colitis to dysplasia and finally to carcinoma. Accumulating evidence suggests that multiple immune-mediated pathways, DNA damage pathways, and pathogens are involved in the pathogenesis of CAC. Over the past decade, there has been an increasing effort to develop clinical approaches that could help improve outcomes for CAC patients. Colonoscopic surveillance plays an important role in reducing the risk of advanced and interval cancers. It is generally recommended that CAC patients undergo endoscopic removal or colectomy. This review summarizes the current understanding of CAC, particularly its epidemiology, mechanisms, and management. It focuses on the mechanisms that contribute to the development of CAC, covering advances in genomics, immunology, and the microbiome; presents evidence for management strategies, including endoscopy and colectomy; and discusses new strategies to interfere with the process and development of CAC. These scientific findings will pave the way for the management of CAC in the near future.
China’s socialist constitutional identity
Authors: Bui Ngoc Son
Published: August 2023

This article explores the dynamics of China’s socialist constitutional identity. It identifies three disharmonic conditions aminating the dynamics: the competing socialist, liberal, universal, and Confucian commitments internal to China’s Constitution; the external discrepancy between the socialist constitutional commitments and social realities; and the normative gap between socialist and generic constitutional identity. The article further generalizes judicial, legislative, activist, and discursive models of dynamics of China’s socialist constitutional identity. Accordingly, China’s socialist constitutional identity is variously shaped by adjudication, legislation, social movement, and public discourse.
Caso Boate Kiss: lições de um maxiprocesso criminal
Authors: Andrade Mauro Fonseca
Published: August 2023

The paper is the result of a research project dedicated to investigating the criminal maxi-trials phenomena in the Brazilian reality. Its first objective is to check if the Boate Kiss Case fits into this phenomenon, considering the different definitions found in literature. The second objective is to analyze the innovations and problems that occurred during the trial proceedings, leading up to the conviction on December 10th, 2021. As for the methodology, the research adheres to a qualitative approach of applied nature, with an explanatory purpose, and employs bibliographical, documentary and case study methods. The theoretical discussion aims to ascertain whether the Boate Kiss Case qualifies as a criminal maxi-trial. In conclusion, it is pointed out that this case aligns with the concept of a criminal maxi-trial, and legislative changes to better regulate maxi-trials according to the requirements of an expedited and fair criminal proceeding are needed.
THE MULTIFACETED LANDSCAPE OF WTO LAW: A COMPREHENSIVE EXAMINATION OF ITS PRINCIPLES, RULES AND INSTITUTIONAL STRUCTURE
Authors: Abuseridze Giga
Published: August 2023

Giga Abuseridze

E-mail: gabuseridze@cu.edu.ge

Ph.D in Law Caucasus University, Georgia

Riga Stradins University, Latvia

https://orcid.org/0000-0003-2868-8719

 

Abstract: This paper examines the fundamental tenets, regulations, and institutional framework of the World Trade Organization that constitute the intricate landscape of WTO jurisprudence.  The author delves into the intricate and specialized character of WTO law, elucidating a diverse array of topics pertaining to the intersection of international trade and legal principles. Particular emphasis is placed on the foundational principles of equitable trade and the WTO, encompassing matters of legal pluralism and non-discrimination. Drawing upon a comprehensive examination of the multilateral panorama of WTO legislation, the presented paper makes a substantial contribution towards fostering a more profound comprehension of international trade regulation, trade transformation, and extant clearances.
Experimental autoimmune encephalomyelitis of mice: Catalytic cross site-specific hydrolysis of H1 histone by IgG antibodies against H1, H2A, H2B, H3, H4 histones, and myelin basic protein
Authors: Urusov Andrey E. , Aulova Kseniya S. , Dmitrenok Pavel S. , Buneva Valentina N. , Nevinsky Georgy A.
Published: August 2023

Introduction: Histones play crucial roles in chromatin functioning and gene transcription, but they are incredibly harmful in intercellular space since they stimulate systemic inflammatory and toxic responses.Myelin basic protein (MBP) is the most meaningful protein of the axon myelin-proteolipid sheath.Antibodies with different enzymatic activities (abzymes) are substantial and specific features of some autoimmune diseases.

Methods: IgG preparations against individual histones (H1, H2A, H2B, H3, and H4) and MBP were obtained from the blood plasma of experimental autoimmune encephalomyelitis-prone C57BL/6 mice by several affinity chromatographies. These antibodies corresponded to different stages of experimental autoimmune encephalomyelitis (EAE) development: spontaneous, MOG (myelin oligodendrocyte glycoprotein), and DNA-histones complex accelerated onset, acute, and remission stages.

Results: IgG-abzymes against MBP and five individual histones demonstrated unusual complex formation polyreactivity and enzymatic cross-reactivity in the specific hydrolysis of histone H1. All IgGs of 3-month-old mice (zero time) against MBP and individual histones demonstrated from 4 to 23 different H1 hydrolysis sites. The spontaneous achievement of EAE during 60 days led to a powerful change in the type and number of H1 hydrolysis sites by IgGs against five histones and MBP. Treatment of mice with MOG and DNA-histones complex results in alteration in IgGs activities, a change in type, and an increase or decrease in the number of H1 hydrolysis sites compared to zero time. The minimum number (4) of different H1 hydrolysis sites was found for IgGs against Н2B (zero time) and Н2A (MOG treatment), while the maximum (26) – against H1 (MOG treatment).

Conclusion: Generally, it first demonstrated that at different stages of EAE evolution, IgG-abzymes against individual histones and MBP could significantly differ in specific sites and their number of H1 hydrolysis. Possible reasons for the catalytic cross-reactivity and strong differences in the number and type of cleavage sites are discussed.
Enteral nutrition support for children with surgical pathology over the periooperative period
Authors: Borovik Tatiana E. , Fomina Мaria V. , Yatsyk Sergey P. , Bushueva Tatyana V. , Zvonkova Nataliya G. , Gusev Аleksey А. , Skvortsova Vera A. , Sokolov Ina , Guseva Irina M. , Fisenko Andrey P. , Alkhasov Abdumanap B.
Published: August 2023

Introduction. The results of treatment of children who are preparing or have already undergone major surgery depend on many factors, including the nutritional status — the presence/absence of malnutrition.
Aim: to assess the nutritional risk and nutritional status in children with surgical diseases during pre- and postoperative periods.
Materials and methods. A prospective, single-center, non-comparative study included 60 children aged from 1 month to
17.5 years with diseases of the esophagus, intestines, urogenital system, admitted for surgical treatment. In all patients, the anamnestic data of life and disease were analyzed, screening of nutritional risk was assessed according to the validated Russian version of the STRONG-kids screening tool, nutritional status was evaluated using the WHO AnthroPlus program (2009) and the anthropometric indices (Z-scores: weight/age, height/age, BMI/age), the biochemical parameters (concentrations of C-reactive protein, total protein, albumin, prealbumin, transferrin) were estimated.
Results. A high nutritional risk at admission was established in more than half (57%) of patients, moderate — in 36% of patients, low — only in 7% of cases. Malnutrition (Z-score BMI/age from –1 to –3) was diagnosed in 24 (40%) patients, 58% of them suffered from diseases of the esophagus, 37% had pathology of the intestine and 36% — the genitourinary system.
Conclusion. Nutritional risk screening and nutrition status assessment are necessary in all patients admitted to pediatric surgical hospitals for the timely appointment of adequate nutritional support, which will reduce the incidence of postoperative complications and decreasing the length of hospital stay.
Problems of medical and social care for children with autism spectrum disorders
Authors: Terletskaya Rimma N. , Lashkova Anna V. , Chernikov Vladislav V. , Vinyarskaya Irina V. , Kuzenkova Lyudmila M.
Published: August 2023

The aim is to identify, through a sociological survey of legitimate representatives of children with autism spectrum disorders (ASD), the problems that they face in their lives, to further improve the provision of medical and social assistance.
Materials and methods. A survey of legal representatives of ASD minors (aged 1–11 years) was conducted.
Results. The study of the living conditions of a child with autism in the family, the assessment by parents of his state of health, problems arising in the registration of disability, in the provision of medical and rehabilitation assistance and issues of medical and social support made it possible to determine the situation of this group of the child population in modern medical and social conditions. The main problems were the collection of a large number of documents during the registration of disability, the long wait for the day of examination, the remoteness of the location of the medical and social examination bureau, the lack of specialist doctors, the lack of consideration of the individual needs of the child when conducting individual rehabilitation programs, the need to contact various institutions and departments, the lack of medical and social assistance, violation of rights in the provision of medical services to a child with autism.
Conclusion. It is necessary both to expand research aimed at studying etiopathogenetic factors and developing strategies for the prevention and early diagnosis of autistic disorders in childhood, destigmatization, and educational work in society.
Urolithiasis in children: modern possibilities of diagnosis and treatment
Authors: Kyarimov Ibragim A.
Published: August 2023

The incidence and prevalence of urolithiasis have been increased over the last decade. Most kidney stones in children are composed of either calcium oxalate or calcium phosphate and often associated with metabolic disorders. Typical symptoms of urolithiasis in children include abdominal or lower back pain, hematuria, and in acute cases dysuria, fever, or vomiting also occur. Ultrasound of the urinary tract is the first choice for children urolithiasis because it can be used to detect most of symptomatic stones. X-rays or computed tomography are also used. Treatment for kidney stones includes diet, drug therapy, and surgery. Surgical treatments for urolithiasis in children include extracorporeal shock wave lithotripsy, contact lithotripsy, percutaneous nephrolithotomy and open lithotomy. This review describes the epidemiology, etiology, pathogenesis, and clinical symptoms and treatment of urolithiasis in children.
Food Hygiene Rating Scheme Online Display in Wales: Executive summary
Authors:   2CV, Research Community
Published: August 2023

Online is increasingly one of the main channels through which consumers interact with food businesses – and research and purchase journeys will often involve multiple channels (online, face-to-face, telephone). It can feel inconsistent that businesses are required to display FHRS ratings on their premises but not online. Indeed, Consumers could see no reason for a distinction between the information available at the physical premises to those online particularly given the increasing role of online food purchase. Consumers are already quite confident navigating the online landscape when it comes to researching and selecting restaurants and takeaways. They are accustomed to making the most of the information available online to make decisions around food. and are not necessarily demanding additional help. A range of criteria (including reviews; word of mouth) is used to help inform choices and decisions around food and hygiene in particular – but this information is vague, haphazard and unreliable. There is a lack of reliable, credible information about food hygiene in the online space. As many regard the FHRS as independent and credible there is some feeling that it would give online sites a “legitimacy” reviews and recommendations do not. Consumers make quick, off-the-cuff decisions when it comes to selecting and researching food. While they are familiar with and will make (at a glance) use of FHRS ratings on businesses’ physical premises, they are not actively seeking these out online where accessing ratings is currently a more involved process requiring navigation to another website. Consumers strongly support mandated FHRS online display and believe it would both help them make better decisions about food and encourage greater compliance by FBOs. FHRS ratings on FBO websites (and other online resources, like food aggregators) would be a useful addition to consumers’ repertoire of information. Consumers also feel FHRS online would have a positive impact on FBOs from a consumer perspective by making them more compliant. Consumers feel it is important that the ratings displayed online are trustworthy, as well as quick and easy to access. Consumers feel that FHRS ratings should be displayed as prominently online as they are on premises i.e. on the landing page. There is also a call for safeguards to be put in place to ensure FBOs can’t display ‘fake’ ratings.
Information Gain Berbasis Algoritma Naive Bayes Classifier Pada Pemodelan Prediksi Kelulusan
Authors: Budianita Avira
Published: August 2023

Salah satu permasalahan yang dihadapi institusi perguruan tinggi adalah tidak tepatnya waktu kelulusan mahasiswa. Setiap tahunnya, jumlah mahasiswa yang mendaftar tidak sebanding dengan jumlah lulusannya. Hal tersebut yang menjadi tugas program studi dalam memantau akademik mahasiswanya. Program studi perlu memiliki acuan untuk mengantisipasi mahasiswa yang berpotensi tidak lulus tepat waktu. Dewasa ini, banyak sekali metode untuk menyelesaikan berbagai permasalahan teknologi informasi salah satunya dengan data mining. Salah satu teknik dalam data mining yang dapat digunakan untuk memprediksi waktu kelulusan adalah klasifikasi dan salah satu algoritma klasifikasi adalah Naive Bayes Classifier (NBC). Penelitian ini menggunakan algoritma NBC dengan memanfaatkan seleksi fitur Information Gain dalam memprediksi waktu kelulusan mahasiswa. Tujuan dari pemanfaatan seleksi fitur sendiri adalah untuk mengurangi tingkat kompleksitas dan meningkatkan akurasi serta mampu mengetahui fitur-fitur apa saja yang paling berkontribusi terhadap tingkat akurasi. Hasil pengolahan dataset pada RapidMiner dengan menerapkan algoritma NBC dengan seleksi fitur Information Gain menunjukkan peningkatan akurasi dibandingkan dengan menggunakan standar NBC.
Elemental and morphological features of thermally modified clinoptilolite as an efficient sorbent for benzo(a)pyrene extraction from water preceding GC – MS analysis
Authors:   University of Niš, Faculty of Medicine, Serbia, Dimitrijević Marija V. , Miladinović Dragoljub L. ,   University of Niš, Faculty of Medicine, Serbia, Ćirić Slobodan A. ,   University of Nis, Faculty of Sciences and Mathematics, Department of Chemistry, Кrstić Nenad S. ,   University of Nis, Faculty of Sciences and Mathematics, Department of Chemistry, Nikolić Jelena S. ,   University of Nis, Faculty of Sciences and Mathematics, Department of Chemistry, Mitić Violeta D. ,   University of Nis, Faculty of Sciences and Mathematics, Department of Chemistry, Stankov Jovanović Vesna P. ,   University of Nis, Faculty of Sciences and Mathematics, Department of Chemistry
Published: August 2023

Monitoring of benzo(a)pyrene (BaP) levels in water is of great importance because BaP is used as a marker for pollution by other polycyclic aromatic hydrocarbons (PAHs). The elemental and morphological features of clinoptilolite used as a sorbent in dispersive micro-solid phase extraction (D-μ-SPE) of BaP from water samples, before Gas Chromatography – Mass Spectrometry determination (GC – MS) is described. SEM micrographs demonstrated agglomerated particles of Clinoptilolite with no changes in particles, but with increased porosity for Clinoptilolite modified at 300 and 400 oC. The content of elements is lower in thermally modified Clinoptilolite at higher temperatures (300 and 400 oC) than for clinoptilolite treated at 120 oC. After the extraction, EDX analysis of clinoptilolite adsorbed BaP, showed the increased percentage of carbon in the modification prepared at 300 oC, indicating the structure of the applied sorbent is more suitable compared to one treated at 400 oC. Recovery values of surrogate standards demonstrate good extraction efficiency for modification at 300 oC and 400 oC, but cheaper modification (prepared at 300 oC) was selected for BaP analysis.
Multi-element analysis of methanol apple peel extracts by inductively coupled plasma-optical emission spectrometry
Authors:   University of Niš, Faculty of Science and Mathematics, Department of Chemistry, Mitić Snežana S. , Stojanović Branka T. ,   University of Niš, Faculty of Science and Mathematics, Department of Chemistry, Mitić Milan N. ,   University of Niš, Faculty of Science and Mathematics, Department of Chemistry, Pavlović Aleksandra N. ,   University of Niš, Faculty of Science and Mathematics, Department of Chemistry, Arsić Biljana ,   University of Niš, Faculty of Science and Mathematics, Department of Chemistry, Stankov Jovanović Vesna ,   University of Niš, Faculty of Science and Mathematics, Department of Chemistry
Published: August 2023

Apples are among the most popular fruits in the world. They are rich in phenolic compounds, pectin, sugars, and a vast number of inorganics beneficial for the human health. In this study, variations of macroelements and microelements contents of five different apple cultivars peel’s methanol extracts from Serbia were investigated, using inductively coupled plasma-optical emission spectrometry and principal component analysis (PCA). Regarding macro elements, K, Na, Ca and Mg are with the highest contents. The most abundant essential element is Fe. Among toxic and potentially toxic elements, only the presence of Al and Sr is registered. The analyzed samples are classified into five groups by PCA.
Peningkatan Aktifitas dan Kemampuan Berpikir Kreatif Melalui Model Pembelajaran Discovery Learning Berbantuan E-Modul
Authors: Ridho Abu Moh. Rasyid , Setyawan Fariz
Published: August 2023

Penyebab utama rendahnya semangat belajar pada mata pelajaran matematika selama daring dan tatap muka terbatas ini adalah bahan ajar yang kurang menarik dan waktu tatap muka yang terbatas. Dalam pembelajaran yang dilakukan melalui Zoom atau WA grup, guru hanya memberikan penjelasan singkat tentang materi dan contoh soal yang sudah ada di e-learning. Selanjutnya, siswa hanya mengerjakan latihan soal dan diperiksa oleh guru tanpa dikonfirmasi. Siswa kurang diberi kesempatan untuk berpikir, mencari tahu, dan memecahkan sendiri materi yang meraka kerjakan yang berdampak pada rendahnya keaktifan dan kemampuan berpikir kreatif siswa dalam pembelajaran. Penelitian ini bertujuan untuk menemukan bahan ajar interaktif yang bisa diimplementasikan dengan model pembelajaran yang dapat menumbuhkan kemampuan berpikir kreatif dalam pembelajaran tatap muka terbatas dan daring. Metode penelitian ini adalah metode penelitian Tindakan kelas yang terdiri dari 2 siklus. Setiap siklus dilaksanakan 2 kali pertemuan. Subjek dalam penelitian ini adalah siswa kelas VII SMP Negeri 1 Nubatukan sebanyak 16 orang. Instrumen penelitian yang digunakan, yaitu lembar observasi keaktifan dan berpikir kreatif siswa. Hasil penelitian menunjukkan bahwa mengalamai peningkatan keaktifan Siklus I dengan rata-rata 65,63 pada siklus I menjadi 76,58 pada siklus II dan persentase siswa yang aktif sebesar 56,25% pada siklus I menjadi 75% pada siklus II. kemampuan berpikir kreatif siswa mengalami peningkatan dengan rata-rata skor kelas pada siklus I adalah 8,625 menjadi 11 pada siklus II dan persentase jumlah siswa yang cukup berpikir kreatif pada siklus I adalah 37,5% menjadi 62,5% pada siklus II.
PROMOTING THE JUNIOR HIGH SCHOOL STUDENTS’ VOCABULARY KNOWLEDGE THROUGH SEMANTIC MAPPING STRATEGY IN WRITING SKILL
Authors: Mbaki Katarina Alviani , Pusparini Ririn
Published: August 2023

The study investigated how teacher encouraged junior high school student’s vocabulary knowledge by using semantic maps on writing skills and examined what vocabulary knowledge could be promoted by semantic mapping through students' report text writing.  This study used a qualitative method, with the research participants being 35 students of SMPN 28 Surabaya consisting of 17 boys and 18 girls. The instruments used in this study were field notes and students’ report text writing. Field note was used to find out how the teacher implemented semantic mapping to encourage students' vocabulary knowledge in writing skill. At the same time, Student writing was used to answer how students' vocabulary knowledge is in the report text and what vocabulary knowledge was promoted by semantic mapping. The outcome of this study showed that the teacher implemented semantic mapping through several stages, such as introducing brainstorming, categorizing, personalizing, and writing. Furthermore, semantic mapping engaged students' attention to always focus on the learning process, assisted them to prepare ideas and information before writing a report text, explored and connected their vocabulary knowledge to the topic.  In addition, based on the results of student report text analysis, which was done in groups, semantic mapping helped them to encourage vocabulary knowledge, classified vocabulary according to its categories and facilitated students to use vocabulary according to the context in the report text. Semantic mapping encouraged three students' vocabulary knowledge: word recognition, word grouping, and word context. By having good vocabulary knowledge, students could produce appropriate report text writing.
How Learning Effectiveness of Taxation Courses and Tax Brevet Training Influence Career Choice in Taxation?
Authors: Kharisma Resti Putri , Sastradipraja Usman
Published: August 2023

Career choice in the field of taxation is one of the employment issues in the field of taxation. Therefore, the Minister of Finance issued several regulations trying to overcome these problems by carrying out various kinds of innovations. This study aims to determine the effect of the effectiveness of learning tax courses and tax brevet training on career choices in taxation. The type of research used is quantitative. The number of samples in this study were 100 respondents, namely students and alumni who were enrolled in the accounting study program at the Unjani Faculty of Economics and Business. Data collection used a questionnaire and was processed using SPSS 25. The results in this study show that partially the effectiveness of learning tax courses has a positive and significant effect on career choices in taxation, tax brevet training partially has no positive and significant effect on career choices in taxation. Simultaneously the variable effectiveness of learning taxation courses and tax brevet training influences career choices in the field of taxation
Increase Entrepreneurial Intentions: Proactive Personality, Entrepreneurship Education, and Academic Support as Predictors
Authors: Aryaningtyas Aurilia Triani , Risyanti Yustina Denik
Published: August 2023

This study conceptualizes entrepreneurship education and academic support as a moderator to understand the mechanism of the relationship between proactive personality and student entrepreneurial intentions. This study proposes a different proactive personality model as a variable influencing students' entrepreneurial intentions, with entrepreneurship education and academic support as a moderating variable. This influence model has never been studied, especially in Semarang. Some previous researchers tend to explore the influence of these factors separately. Observations from 192 students at ten universities in Semarang were used to test the hypothesized model. The study used a quota sampling technique and data collection was carried out by distributing questionnaires. The effect moderation model was tested using tiered regression analysis, with the Moderated Regression Analysis (MRA) interaction test. The results showed that the effect of proactive personality and entrepreneurial intentions of students was stronger when entrepreneurship education and academic support were included in the interaction. These findings are consistent with existing theory and studies. In addition, as a managerial implication, this study provides advice to tertiary institutions as educational institutions to consider proactive personality, entrepreneurship education, and academic support as necessary factors to encourage student interest in entrepreneurship. Entrepreneurship teaching methods should also be explored further.
Analisis Persepsi Konsumen Terhadap Keputusan Pembelian Pada Perumahan Grand Residence Makale Kabupaten Tana Toraja
Authors: Tapparan Samuel Randy , Justian Justian , Nursita Lisa
Published: August 2023

Abstract

This study aims to determine how consumers' perceptions of purchasing decisions at Grand Residence Makale Housing, Tana Toraja Regency. This type of research is descriptive quantitative research and data collection techniques carried out in this research are field research and library research. The data collection procedure was carried out by means of observation, interviews, and documentation. The types of data used are primary data and secondary data. The percentage of the highest average perception per indicator is 68.4% of all indicators that the Makale Grand Residence housing does have a good or positive perception 

Keywords: Perception, Consumer, Purchase decision.
PENGARUH HARGA DAN KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN PADA CAFE WAI TEMAN MINUM KAMU DI KECAMATAN RANTEPAO KABUPATEN TORAJA UTARA
Authors: Ismail Ahsani Paramita , Pandung Klarita Belo , Tapparan Samuel Randy
Published: August 2023

Abstract

 

This study aims to determine the effect of price and service quality on customer satisfaction at Cafe” Wai Teman Minum  Kamu” in Rantepao District, North Toraja Regency. The type of research used in this research is descriptive quantitative research using multiple regression analysis techniques. The data collection method is by using a questionnaire / questionnaire. The population used are consumers who have come to  Wai Teman Minum Kamu Cafe, while the method used to determine the number of samples is using the Slovin formula as many as 65 people. The results of the study stated that price had a significant effect on customer satisfaction, while service quality had no significant effect on customer satisfaction.  

Keywords: price, service quality and customer satisfaction.

 

Abstrak

 

Penelitian ini bertujuan untuk mengetahui pengaruh harga dan kualitas pelayanan terhadap kepuasan konsumen pada Cafe “Wai Teman  Minum Kamu “ di Kecamatan Rantepao Kabupaten  Toraja Utara. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian deskriptif kuantitatif dengan menggunakan teknik analisis regresi berganda.Metode Pengumpulan data yaitu dengan mengunakan angket /  kuosiener.  Populasi yang digunakan adalah para konsumen yang pernah datang di Café Wai Teman Minum Kamu, sedangkan metode yang digunakan untuk menentukan jumlah sampel adalah menggunakan rumus Slovin sebanyak 65 orang. Hasil penelitian menyatakan bahwa harga berpengaruh signifikan terhadap kepuasan konsumen, sedangkan kualitas pelayanan tidak berpengaruh signifikan terhadap kepuasan konsumen.

Kata Kunci : harga, kualitas pelayanan dan kepuasan konsumen.
Dermatofibrosarcoma Protuberans; Case Report in a Pediatric Patient
Authors:   Hospital Regional “León” del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. León, Guanajuato, México., Sánchez Gutiérrez Karla Itzel , Castro Cortés Samanta ,   Hospital Regional “León” del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. León, Guanajuato, México. Hospital Regional “León” del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. León, Guanajuato, México., Quintero Sierra Manuel Enrique ,   Hospital Regional “León” del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. León, Guanajuato, México. Hospital Regional “León” del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado. León, Guanajuato, México.
Published: August 2023

Dermatofibrosarcoma protuberans (DFSP) is a rare and locally aggressive mesenchymal neoplasm arising from the dermal and subcutaneous tissues. It typically manifests as a slow-growing, firm, protuberant or plaque-like lesion on the skin. DFSP predominantly affects young to middle-aged adults, with a slight predilection for females. This tumor exhibits a distinctive infiltrative growth pattern, characterized by tumor cells invading the surrounding tissues, including the deep subcutaneous layers and the underlying fascia. Histopathologically, DFSP presents characteristic features, such as the presence of spindle-shaped tumor cells arranged in a "storiform" pattern, as well as the presence of a prominent "honeycomb" appearance due to the presence of multinucleated giant cells. Immunohistochemical staining is essential to confirm the diagnosis, with positivity for CD34 being a hallmark of DFSP. Although DFSP rarely metastasizes, its extensive local invasion and high recurrence rate necessitate a wide surgical excision with clear margins as the mainstay of treatment. The use of Mohs micrographic surgery or adjuvant radiation therapy has demonstrated favorable outcomes in cases with challenging anatomical locations or microscopically positive margins. Imatinib mesylate, a tyrosine kinase inhibitor, has also emerged as a promising systemic therapy for advanced or unresectable DFSP, particularly cases with the COL1A1-PDGFB gene fusion, which represents the molecular hallmark of DFSP. Early diagnosis and appropriate management are crucial to achieving optimal outcomes in DFSP. This article provides a comprehensive review of the clinical, histopathological, and molecular aspects of DFSP, highlighting the significance of a multidisciplinary approach to ensure accurate diagnosis and tailored therapeutic strategies for patients affected by this rare dermatological neoplasm.
The Influence of Maybrat Accents towards Eleventh Grade Students English Pronunciation
Authors:   Universitas Mercu Buana Yogyakarta, Teresa Naa Maria , Setyawan Agustinus Hary ,   Universitas Mercu Buana Yogyakarta
Published: August 2023

The research was applying qualitative method and instruments to collect data such as reading text which consisted of some words, phrases and sentences. Collecting data carried out by recording twenty students English reading. The students were at the eleventh grade of SMA Negeri 1 Ayamaru, Maybrat Regency, Southwest Papua Province. The student records were used for analyzing English speech sound in both aspects segmental and suprasegmental of the students’ pronunciation. The result of students record exposed the difference between the students English speech sound and the recognizable English speech sound in English standard variety. It was found that the differences were revealed in vowel sounds and was sounded by the students in English single syllable words. The suprasegmental features were different represented by the student speech sound either in words stress, phonemic stressed, length, loudness and intonation or the pitch / tone and sounds inserted and gliding into single syllable segment.
The Effect of Incremental Capital Output Ratio (ICOR), Labor Force Participation Rate (TPAK) and Index Human Development (IPM) Against Economic Growth in Indonesia
Authors:   Study Masters Program in Economics, Faculty of Economics and Business, Syiah Kuala University Banda Aceh, Indonesia, Junaidi Junaidi , Silvia Vivi ,   Study Masters Program in Economics, Faculty of Economics and Business, Syiah Kuala University Banda Aceh, Indonesia, Abrar M. ,   Study Masters Program in Economics, Faculty of Economics and Business, Syiah Kuala University Banda Aceh, Indonesia
Published: August 2023

The purpose of this study was to examine and analyze the influence of Incramental Capital Output Ratio (ICOR),Labor Force Participation Rate (TPAK), and Human Development Index (IPM) on Economic Growth at 33 provinces in Indonesia during the 2011-2022 period. The research used Panel Data regression, after carrying out the Chow test and Hausman test and Langrange Multiplier test, the estimation used was the Random Effect Model (REM). The results of testing the model with ÿ=5 percent show that ICOR and the Human Development Index have a significant positive effect on Economic Growth in Indonesia, while the Labor Force Participation Rate has no effect on Economic Growth in Indonesia. Therefore, the Indonesian government should be able to make policies that are able to encourage increased investment that needs to be realized and developed so that the capital stock can be optimally utilized to accelerate economic growth. The government should also encourage formal education to increase technical capabilities for more skilled workers so that they can adapt to the required competency needs. Then the Indonesian governmentcan also make policies that are able to encourage the welfare and quality of society to encourage economic growth such as equal distribution of education and health services for all people, in addition to increasing social insurance for all people.
Pengaruh Promosi dan Harga Terhadap Minat Beli Pelanggan PT. Nipsea Paint and Chemicals Cat Nippon Paint
Authors: Sukaryono Dedi
Published: August 2023

ABSTRACT This study aims to determine the effect of promotion and price on customer buying interest at PT. Nipsea Paint And Chemicals deppo Malang. This research is a quantitative study. The population in this study is the consumers of PT. Nipsea Paint And Chemicals Deppo Malang. The sample used was 100 respondents with purposive sampling technique. The data analysis techniques used are validity and reliability tests, classical assumption tests (normality test, multicollinearity, heteroscedasticity, and autocorrelation test, multiple linear regression analysis, simultaneous test (F test), partial test (t test). of Promotion (X1) on Customer Buying Interest (Y). Partially there is a significant effect of Price (X2) on Customer's Buying Interest (Y). Simultaneously there is a positive and significant effect of Promotion (X1) and Appreciation (X2) on Interest Buy Customer (Y).Keywords: Promotion, price and Buying Interest of Customers ABSTRAKPenelitian ini bertujuan mengetahui pengaruh Promosi dan Harga terhadap Minat Beli Pelanggan PT.Nipsea Paint And Chemicals deppo Malang.Penelitian ini merupakan penelitian kuantitatif. Populasi dalam penelitian ini adalah Konsumen PT.Nipsea Paint And Chemicals Deppo Malang. Sampel yang digunakan sebanyak 100 responden dengan teknik pengambilan purposive smpling. Teknik analisis data yang digunakan yaitu uji validitasdan reliabilitas, uji asumsi klasik (uji normalitas, multikolinieritas, heteroskedastisitas, dan uji autokorelasi,analisisregresi linear berganda,uji simultan (uji F), uji parsial (uji t).Hasil penelitian Secara parsial terdapat pengaruh signifikan dari Promosi (X1) terhadap Minat Beli Pelanggan (Y). Secara parsial terdapat pengaruhsignifikan dari Harga (X2)terhadap Minat Beli Pelanggan (Y). Secara simultan terdapat pengaruh yang positif dan signifikan dari Promosi (X1) dan Hargai (X2) terhadap Minat Beli Pelanggan (Y).Kata Kunci: Promosi, harga dan Minat Beli Pelanggan
Pengaruh Gaya Kepemimpinan Dan Motivasi Kerja Terhadap Kinerja Karyawan Pada PT. Tirta Sukses Perkasa Pandaan
Authors: Ananda Anton Ferry , Afif Muhammad , Wahyuni Fia Sari
Published: August 2023

Abstract This study aims to determine the effect of leadership style and work motivation on employee performance at PT. Tirta Success Mighty Pandaan. This research is a quantitative study, the population in this study are employees of PT. Tirta Sukses Perkasa Pandaan and the sample in the study with the incidental sampling technique. The data analysis technique used is validity test, reliability test, classical assumption test and multiple linear regression analysis test. The results of the study show that leadership style has a significant effect on employee performance at PT. Tirta Success Mighty Pandaan. Work motivation has a significant effect on employee performance at PT. Tirta Success Mighty Pandaan. Leadership style and work motivation have a significant effect on employee performance at PT. Tirta Success Mighty Pandaan. Based on the research results, there is a dominant influence on employee performance at PT. Tirta Sukses Perkasa Pandaan namely work motivation. Indicators of work motivation consist of physiological needs, safety needs, social needs, esteem needs and self-actualization needs.Keywords: Leadership style, work motivation, employee performance  Abstraksi Penelitian ini bertujuan untuk mengetahui pengaruh gaya kepemimpinan dan motivasi kerja terhadap kinerja karyawan pada PT. Tirta Sukses Perkasa Pandaan. Penelitian ini merupakan penelitian kuantitatif, populasi dalam penelitian ini adalah karyawan PT. Tirta Sukses Perkasa Pandaan dan sampel pada penelitian dengan teknik pengambilan sampling incidental. Teknik analisis data yang digunakan yaitu uji validitas, uji reliabilitas, uji asumsi klasik dan uji analisis regresi linier berganda. Hasil pada penelitian menunjukkan, bahwa gaya kepemimpinan berpengaruh signifikan terhadap kinerja karyawan pada PT. Tirta Sukses Perkasa Pandaan. Motivasi kerja berpengaruh signifikan terhadap kinerja karyawan pada PT. Tirta Sukses Perkasa Pandaan. Gaya kepemimpinan dan motivasi kerja berpengaruh signifikan terhadap kinerja karyawan pada PT. Tirta Sukses Perkasa Pandaan. Berdasarkan hasil penelitian terdapat pengaruh yang paling dominan terhadap kinerja karyawan pada PT. Tirta Sukses Perkasa Pandaan yaitu motivasi kerja. Indikator pada motivasi kerja terdiri dari  kebutuhan fisiologis, kebutuhan rasa aman, kebutuhan sosial, kebutuhan akan perghargaan dan kebutuhan perwujudan diri.Kata Kunci: Gaya kepemimpinan, motivasi kerja, kinerja karyawan
A CRIANÇA DA EDUCAÇÃO INFANTIL E SEU DIREITO DE PENSAR SOBRE A LINGUAGEM ESCRITA
Authors: Pena Selma Costa , Azevedo Heloísa Helena Oliveira de , Oliveira Douglas Almeida de
Published: August 2023

O artigo discute a necessidade de ações sistemáticas que assegurem as especificidades do trabalho pedagógico direcionado à linguagem escrita com crianças da educação infantil. Resulta de trabalho desenvolvido com narrativas de futuros professores do curso de Pedagogia da Universidade Federal do Pará. Toma como parâmetro teórico, estudos de autores que discutem a linguagem escrita numa perspectiva dialógico-discursiva e a narrativa como dispositivo investigativo. Os resultados indicam que as narrativas possibilitaram discussões sobre modelos de leitura e de leitor construídos ao longo dos anos, a compreensão de algumas polarizações acerca da temática a exemplo da “velha”, mas não resolvida, discussão sobre alfabetizar ou não na educação infantil.
Pelatihan Manajemen Dan Legalitas Usaha Di Gampong Jojo Kecamatan Mutiara Timur Kabupaten Pidie
Authors: Herizal Herizal , Abdullah Husaini
Published: August 2023

Setiap kegiatan usaha yang dilakukan haruslah memiliki pengetahuan yang memadai. Hal ini diperlukan untuk menghindari terjadinya kerugian dalam melakukan kegiatan usaha. Selain itu, legalitas sebuah badan usaha juga diperlukan sebagai legal standing dalam menjalankan usaha, bentuk dari legalitas usaha antara lain nama usaha, ijin operasional dan kepengurusannya. Pelatihan manajemen dan legalitas usaha sangat penting bagi pelaku usaha baik usaha skala yang kecil sampai yang besar. Peningkatan  produktivitas usaha, akan berdampak luas pada perbaikan kesejahteraan masyarakat karena melalui kegiatan usaha tersebut sebagian masyarakat menggantungkan   sumber kehidupannya. Salah satu alternatif  dalam  meningkatkan  produktivitas  usaha adalah dengan  melakukan pelatihan manajemen dan legalitas usaha yang sistemik sehingga akan memberikan dampak yang lebih luas bagi masyarakat.Kata kunci: Manajemen  dan Legalitas
Computer 3D Animation Use and Its Effect on Secondary School Students’ Conceptual Understanding of Mammalian Circulatory System in Kiambu County, Kenya
Authors: Rogers Hassan Bob , Orado Dr. Grace N. , Nasibi Dr. Mary
Published: August 2023

When students lack the basic information required to appreciate specific biological issues, they may believe biology is a difficult subject to learn. It may be easier to teach abstract biological processes or concepts in biology classes with the help of 3D computer animation, which may improve students’ recall and retention of knowledge of the lesson being taught and increase motivation and engagement in the learning process. The main objective of this study was to determine the effect of computer 3D animation in enhancing students ’conceptual understanding of the mammalian circulatory system: structures, functions, and blood circulation in the mammalian heart. The study design was quasi-experimental. In order to gather data before and after treatment, pretests and posttests were given to students placed in the experimental and control groups. One hundred sixty students, eighty in each group, comprised the study’s sample size. The performance of students in the experimental group showed that computerized 3D animation treatment was effective in improving students’ conceptual understanding of the mammalian circulatory system as well as their retention of key biological terminologies as compared to students in the control group taught using conventional techniques, which resulted in no significant change in performance-conceptual understanding. Pretest and post-test items were reviewed by biology teachers and subject experts before being administered to students to validate test items. Additionally, it is advised that teachers be given the fundamental training necessary to operate or handle C3D animations and that C3D animations be made available to teachers and students in school libraries.
Supportive Environment for Better Data Management Stage in the Cycle of ML Process
Authors: Alkhaled Lama , Khamis Taha
Published: August 2023

The objective of this study is to explore the process of developing artificial intelligence and machine learning (ML) applications to establish an optimal support environment. The primary stages of ML include problem understanding, data management (DM), model building, model deployment, and maintenance. This paper specifically focuses on examining the DM stage of ML development and the challenges it presents, as it is crucial for achieving accurate end models. During this stage, the major obstacle encountered was the scarcity of adequate data for model training, particularly in domains where data confidentiality is a concern. The work aimed to construct and enhance a framework that would assist researchers and developers in addressing the insufficiency of data during the DM stage. The framework incorporates various data augmentation techniques, enabling the generation of new data from the original dataset along with all the required files for detection challenges. This augmentation process improves the overall performance of ML applications by increasing both the quantity and quality of available data, thereby providing the model with the best possible input.
 
Received: 16 June 2023 | Revised: 24 July 2023 | Accepted: 9 August 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
Data sharing is not applicable to this article as no new data were created or analyzed in this study.