bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of Six Sigma Methodology to Reduce High Defect Rate in Rubber Processing Industry
Authors: Setiawan Shafira Alamanda
Published: February 2025

PT Jaya Makmur is a company that specializing in processing of rubber pipe parts. A high defect rate in the production process has emerged as a critical issue that negatively affecting product quality, company’s reputation, and overall profitability. Defect types such as “Hole” and “Fracture” have been the most prevalent and significant type of defect that occurs in the production amounting to 20% to 30% per month surpassing the 15% threshold. This have led to the defective products being sent to the customers. As a result, the company has faced an increase in number of rework and the need for additional production schedules to meet customer demands, which in return has escalated operational costs. Due to the complexity of the defect patterns, a systematic approach was required to identify, analyze, and address the underlying causes of these defects. Implementing a structured methodology like Six Sigma become important to reduce defect rate and gain customer satisfaction. This would allow the company to maintain its competitive edge in the rubber processing industry by consistently delivering high-quality products. This research was conducted to investigate the root causes of the high defect rate and propose solutions for defect reduction using the systematic approach Six Sigma DMAIC (Define, Measure, Analyze, Improve, Control) methodology. In the Define phase, problem was identified by reviewing internal production data which showed high defect rate that above acceptable limits for certain products, particularly 63MM Z-Joint Ring. Measure phase utilized control charts to monitor the process stability and variability. Pareto analysis showed that the most frequent defects were “Holes” and “Fractures”. To identify the root causes of this significant defect types, fishbone diagram was utilized in Analyze phase. The Improve phase focused on addressing these root causes by implementing targeted solutions. In the final Control phase, the improvements were standardized and monitored through control charts and key performance indicators (KPIs). This to ensure that the production process remained stable and that defect rates continued to decrease over time.
Pengaruh Opini Audit, Temuan Audit, dan Tindak Lanjut Hasil Audit terhadap Tingkat Korupsi: Studi Empiris pada Pemerintahan Kabupaten/Kota di Provinsi Sumatera Barat Tahun 2019-2021
Authors: Muhardimansyah Muhardimansyah , Arza Fefri Indra
Published: February 2025

This study aims to examine the effect of audit opinion, audit findings, and follow-up on the level of corruption. This type of research is causal associative with a quantitative approach. The population used in this study were all district / city local governments in West Sumatra Province in 2019-2021. The sampling technique in this study used a total sampling technique, there were 57 samples used as research samples. The data used in this study are secondary data obtained from the audit results of the Financial Audit Agency of the Republic of Indonesia, the Central Bureau of Statistics, the West Sumatra High Prosecutor's Office and the official website of each agency. The analysis method used is the multiple regression method. The results showed that audit opinion and audit findings have a positive effect on the level of corruption, follow-up on audit results has a negative effect on the level of corruption. Simultaneously, these variables have a significant influence on the level of corruption.
Pengaruh Opini Audit, Reputasi KAP, dan Financial Distress terhadap Auditor Switching
Authors: Abdi Aisha Nabila , Handayani Dian Fitria
Published: February 2025

This study aims to examine the impact of audit opinion, the reputation of the KAP (Public Accounting Firm), and financial difficulties on auditor turnover. The data used in this study consists of annual financial reports from manufacturing companies listed on the Indonesia Stock Exchange (IDX) during the period from 2018 to 2022. The purposive sampling method was applied to select the data. Logistic regression analysis was employed to analyze the data. The study's findings indicate that audit opinion is associated with auditor turnover, while the reputation of the KAP is negatively related to auditor turnover. Additionally, financial difficulties are found to be related to auditor turnover. Future studies could consider including other variables, such as audit fees and audit delays, as well as other factors that might influence auditor turnover.
Lesson Study in Pre-Service Biology Teacher Education at Universitas Riau
Authors: Suryawati Evi , Rahmi Fitri Olvia , Dianti Putri Rahma , Harfal Zaldi , Nengsih Dwi Tira
Published: February 2025

The Teacher Professional Education (TPE) Program aims to train qualified teachers by providing structured training and learning programs through Field Experience Practice (EP), which was implemented in schools in two cycles: EP 1 and EP 2, using the Lesson Study format. Both cycles of EP involved 1 tutor teacher, 2 observer teachers, 1 supervising lecturer, and 5 TPE students. Each cycle goes through 3 phases: Plan, Do, and See. The results of profiling showed that the students' characteristics were kinesthetic and audio-visual. The learning model used is problem-based learning, and based on observations of independent learning activities and collaboration in completing their assignments, all deficiencies are addressed during reflection activities. In the final stage of the learning activities, each party involved in the Lesson Study activities obtained valuable lessons. The supervisors received insights to apply improvements to courses related to the TPE program
PENGEMBANGAN E-LKPD BERBASIS HOTS (Higher Order Thinking Skills) PADA MATA PELAJARAN EKONOMI DI SMA KARTIKATAMA
Authors: Sholiha Sangidatus , Zelpita Dela
Published: February 2025

Evaluasi pembelajaran di SMA Kartikatama Metro masih menggunakan metode konvensional yakni menggunakan kertas lembaran untuk dikerjakan siswa secara manual. Hal ini menyebabkan proses penilaian membutuhkan waktu yang lama sehingga memperlambat penyampaian hasil belajar. Tujuan Penelitian ini yakni untuk menghasilkan aplikasi evaluasi berbasis HOTS (Higher Order Thinking Skills) pembelajaran yang valid dan praktis. Penelitian ini menggunakan pendekatan Research and Development (R&D) dengan model pengembangan ADDIE (Analysis, Design, Development, Implementation, Evaluation) dan subjek penelitian siswa kela X SMA Kartikatama. Teknik pengumpalan dari angket validasi ahli materi, validasi ahli media dan angket respon peserta didik. Hasil penelitian menunjukkan bahwa E-LKPD yang dikembangkan validasi ahli  media dengan skor 95% dan validasi ahli materi  materi 88,5%. Uji kepraktisan menunjukkan respon positif dari peserta didik dengan skor lebih dari 60%. Pengembangan E-LKPD berbasis HOTS ini berhasil mengintegrasikan teknologi digital dalam pembelajaran ekonomi dan mendukung pengembangan kemampuan berpikir tingkat tinggi siswa. Penelitian ini memberikan kontribusi dalam pengembangan media pembelajaran inovatif yang dapat mendukung proses pembelajaran aktif dan berpusat pada siswa
Attitude Towards Green dan Enviromental Friendly Activity sebagai Pendorong untuk Meningkatkan Kunjungan ke Semarang Zoo
Authors: Pamuja Yobel Uri , Athanasius Sentot Suciarto
Published: February 2025

This research aims to determine interest in revisiting green tourist attractions that preserve the animals at Semarang Zoo. A sample of 96 visitors was taken from the population of all Semarang Zoo visitors. The data collection technique was carried out using a questionnaire. The research results showed that respondents were interested in visiting again and were interested in recommending it to others. The two variables attitude towards green or attitude that cares about the environment and environmental friendly activity or activities that care about the environment have a positive and significant effect on interest in returning to visit. Semarang Zoo should be able to increase the natural beauty of the Semarang Zoo tourist attraction. This can be done by rearranging the plants and arranging the animal enclosures so that it is more comfortable for visitors to walk around and spend more time at Semarang Zoo. It would be better if there are more Instagrammable spots and tags for selfie photos and uploading them on social media
Experiences and Challenges of Mothers in Caring for Infants with Delayed Developmental Milestones: A Case of Dodoma Region, Tanzania
Authors:   Department of Clinical Nursing, School of Nursing and Public Health, Department of Public Health, School of Nursing and Public Health, University of Dodoma, Dodoma, Tanzania, Gemuhay Helena Marco , Ali Saada , Kibusi Stephen
Published: February 2025

ABSTRACT
Background: Delayed Developmental Milestones is a physical disability affecting the child development, occurs when the child fails to attain normal milestones compared to other children. Globally, 180-200 million infants have signs of developmental delay, and 86% are from developing countries. In Dar es Salaam, proportion of children with cognitive delay is 12.3%.
Objectives: This study explored the experiences and challenges of mothers in caring for infants with delayed developmental milestones.
Methods: In-depth interviews with ten mothers explored their experiences and identified challenges they encountered while caring for infants with delayed developmental milestones. NVIVO plus software was used for content analysis.
Results: Results showed that parents raising infants with delayed developmental milestones had negative experiences on the cause and types of delayed milestones. They lost hope. They were facing different challenges like lack of specialists, conflict in marriage and stigma.
Conclusion: Mothers of infants with delayed developmental milestones had negative experiences about this problem and they face many challenges in caring the infants.
Depuration of mussels (Pilsbryoconcha exilis) from microplastics using banana peel adsorbents in coastal areas of Indonesia
Authors: Daud Anwar , Birawida Agus Bintara , Ambeng Ambeng , Sila Nurlia , Aziz Muhammad Fahmi , Putro Gurendro
Published: February 2025

Global contamination of the marine environment by plastics has led to the discovery of microplastics in various marine species, including those for human consumption. Depuration reduces the concentration of microplastics and in turn, reduces human exposure to microplastics that enter the human body. This study looked at the effectiveness of microplastic depuration on Pilsbryoconcha exilis using a natural adsorbent from banana peel. An investigation was also conducted on effectiveness by time variation to determine the most viable depuration time. A completely randomised design was employed with two repetitions of mussel treatment for durations of 12, 24, and 36 h. The results showed that the effectiveness of depuration by time variation was fluctuating. The most effective depuration time was 12 h. The highest average concentration of microplastics, 0.555 MPs∙ind–1, occurred after 24 h of depuration, while the lowest, 0.370 MPs∙ind–1, did after 12 h of depuration. Dry banana peel as a depuration adsorbent was proven to reduce the number of microplastics. More research is needed on depuration and the most effective types of adsorbents. Research like this will help many people reduce the quantity of microplastics that enter the body.
Predicting plant establishment: Germination responses of five Arrhenatherion alliance species from two distinct climatic origins
Authors: Pradita Faisal A. , Janicka Maria
Published: February 2025

The lowland hay meadows conservation status is increasingly at risk due to improper management and climate change, threatening plant communities, including Arrhenatherion alliance. As a result, species enrichment is required. However, natural plant self-establishment remains challenging due to the high variability in germination, largely caused by climate factors. Thus, a germination test is suggested before directly sowing local seeds in the field. Therefore, this study aimed to investigate how germination characteristics of five local species are affected by the interplay between species and weather factors, specifically mean temperature and total rainfall during seed filling and ripening. During warm, dry periods, the seed mass of Campanula patula L. and Centaurea jacea L. was higher (0.04 g and 1.87 g, respectively), whereas in wet periods, the seed mass of Achillea millefolium L. (0.10 g), Plantago lanceolata L. (1.24 g), and Tragopogon pratensis L. (7.41 g) was higher. The germination capacity was significantly affected by species-specific factors. Seeds of A. millefolium and T. pratensis during wetter years showed higher germination rates than other species, which exhibited the opposite trend. Additionally, a wetter collection period shortened t50 (time required for 50% germination) in all species except A. millefolium and T. pratensis, while C. patula remained unaffected in both years. A positive correlation was observed between seed mass, germination capacity, and speed, while a negative correlation with t50. Hence, an increase in seed mass leads to a reduced t50 duration. According to our findings, seed mass may serve as a reliable predictor of plant establishment in the field.
Enhancing broiler growth, carcass quality, blood parameters and intestinal microbial load: the role of dietary garlic powder as a natural growth promoter
Authors: Deeb Salma E. , Ashour Elwy A. , Youssef Islam M. , Alshehry Garsa , Abuljadayel Dalia A. , Aljahdali Nesreen , Albaqami Najah M. , Bahnas Marwa M. , Abd El-Hack Mohamed E.
Published: February 2025

This study evaluated the effects of garlic powder (GP) as a natural growth promoter in broiler diets, replacing traditional antibiotics. Four experimental groups of 264-day-old broiler chicks (Ross 308) were established in a fully randomized design experiment. Each group had six replicates, each with eleven unsexed chicks. The treatments were used as follows: The 1st group was the basal diet without any additive (control group). 2nd, 3rd and 4th groups (1 GP, 2 GP and 3 GP) receving basal diet + 1, 2, and 3 g GP/kg feed, respectively. Results demonstrated that 2 and 3 g GP/kg diets significantly improved feed conversion ratio (FCR), while 1 g GP/kg feed led to the greatest gains in body weight, weight gain, and feed intake. Blood analysis revealed elevated total protein, albumin, and A/G ratios across all GP groups, alongside reduced creatinine and ALT levels. The 3 g GP/kg diet notably increased HDL and reduced total cholesterol (TC) and LDL concentrations. Immunoglobulin Y (IgY) levels were highest in birds fed 1 and 3 g GP/kg, with IgM levels peaking in the 1 g GP group. Additionally, the 3 g GP/kg diet enhanced superoxide dismutase (SOD) activity and reduced malondialdehyde (MDA) levels, a marker of oxidative stress. In contrast, the control group exhibited the highest MDA levels.

Additionally, the highest lactic acid bacteria (LAB) and total bacterial count (TBC) are found in the 1 GP group. However, the control group had the highest levels of E. coli. In conclusion, incorporating garlic powder into broiler diets enhanced immune response, blood parameters, overall growth, and gut bacteria counts with optimal effects observed at 1 and 3 g GP/kg.
Investigating the behavioral implications of microplastic exposure in animal species
Authors: Hamidian Amir Hossein , Feizi Meisam
Published: February 2025

Microplastics (MPs) are pervasive pollutants impacting ecosystems worldwide, causing physical harm and behavioral changes in wildlife. MP toxicity mainly depends on size, porosity, weathering, and surrounding compounds. MPs disrupt feeding and metabolism, resulting in reproductive, neurological, and behavioral disorders. These impacts significantly alter ecological niches and reduce animal survival. Understanding these impacts is crucial for assessing the broader ecological effects of plastic pollution and developing effective mitigation strategies. This review investigated 110 papers on quantifying the behavioral consequences of MPs while considering their_physiological basis, emphasizing the significance of these changes and their potential long-term influence on populations and ecosystems. This study thoroughly investigates model species, including plankton, fish, amphibians, crustaceans, pollinators, and mammals. Fish exhibited the most significant behavioral impact, while crustaceans showed the least. Mice, representing mammals, displayed the most severe physiological damage.
Effect of sleep quality on weaning from mechanical ventilation: A scoping review
Authors: Locihová Hana , Jarošová Darja , Šrámková Karolína , Slonková Jana , Zoubková Renáta , Maternová Klára , Šonka Karel
Published: February 2025

Introduction

Mechanically ventilated patients have disturbed sleep.

Aim of the study

To explore whether there is a relationship between successful or unsuccessful weaning of patients and their sleep quality and circadian rhythm.

Materials and Methods

A scoping review. The search process involved four online databases: CINAHL, MEDLINE, ProQuest, and ScienceDirect. Original studies published between January 2020 and October 2022 were included in the review.

Results

Six studies met the inclusion criteria. These studies showed that patients with difficult weaning were more likely to have atypical sleep, shorter REM sleep, and reduced melatonin metabolite excretion. Muscle weakness was an independent factor associated with prolonged weaning from mechanical ventilation and was significantly more frequent in patients with atypical sleep. Heterogeneous patient samples and the methodology of the studies hamper a clear interpretation of the results.

Conclusions

A relationship was found between abnormal sleep patterns, reduced melatonin metabolite (6-sulfa-toxymelatonin) excretion, and unsuccessful weaning. However, the causality is not clear from the existing research.
Expatriates at the Polls: An analysis of predictors affecting voter participation in the 2019 EU Elections
Authors: Stancea Andreea , Ciocîrlan Cecilia , Andrei Despina
Published: February 2025

In the wake of the 2024 elections, far-right parties have capitalized on prevailing social and economic grievances to expand their electoral base. These parties raised issues such as immigration, national security, and economic dissatisfaction to appeal to voters seeking drastic changes from the status quo. This paper focuses on expatriates’ voter turnout in the last 2019 European elections and examines whether the turnout of the European elections is influenced by the period expatriates have been living in another EU country. Additionally, this paper aims at testing if expatriates are more inclined to have an extreme political orientation than non-expatriates. Employing several logistic regression models to examine the effects between different types of determinants and turnout and extreme political orientation, this paper aims at testing to what extent the period of residence, perception of the economic situation, trust and European views influence the expatriates’ voters to go to the polls.
Uniform Distribution of αn Modulo One for A family of Integer Sequences
Authors: Weingartner Andreas
Published: February 2025

We show that the sequence (αn)
n

∈ℬ is uniformly distributed modulo 1, for every irrational α, provided ℬ belongs to a certain family of integer sequences, which includes the prime, almost prime, squarefree, practical, densely divisible and lexicographical numbers. We also give an estimate for the discrepancy if α has finite irrationality measure.
Uniform Dual Approximation to Veronese Curves in Small Dimension
Authors: Schleischitz Johannes
Published: February 2025

We refine upper bounds for the classical exponents of uniform approximation for a linear form on the Veronese curve in dimension from 3 to 9. For dimension three, this in particular shows that a bound previously obtained by two different methods is not sharp. Our proof involves parametric geometry of numbers and investigation of geometric properties of best approximation polynomials. Slightly stronger bounds have been obtained by Poels with a different method contemporarily. In fact, we obtain his bounds as a conditional result.
PERAN BRAND IMAGE MEMEDIASI PENGARUH E-WOM TERHADAP KEPUTUSAN PEMBELIAN PRODUK SMARTPHONE OPPO DI KOTA DENPASAR
Authors: Pratama Muhammad Roni , Kusumadewi Ni Made Wulandari
Published: February 2025

Rapid development of communication technology has made the need for smartphones increasing. This can be seen from the community even more concerned with smartphones than socializing with friends or relatives in the surrounding environment. So that it becomes a great opportunity for smartphone companies to market their products to a wider market share. This study aims to determine the role of Brand image in mediating the influence of E-WOM on the purchase decision of Oppo smartphone products in Denpasar City. This research was conducted on Oppo smartphone products using non-probability sampling methods, especially purposive sampling. The number of respondents in this study were 100 respondents. The results of the analysis of this study are E-WOM has a positive and significant effect on purchasing decisions, E-WOM has a positive and significant effect on Brand image, Brand image has a positive and significant effect on purchasing decisions, Brand image is able to mediate the influence of E-WOM on purchasing decisions Based on the results of this study, it is hoped that Oppo can pay attention to good E-WOM on internet media in the hope of being able to improve Oppo's Brand image so that it influences purchasing decisions.
Keywords: E-WOM; Brand image; Purchase decision
PENGARUH LAYOUT DAN PENJADWALAN PRODUKSI TERHADAP KELANCARAN PROSES PRODUKSI PADA PERUSAHAAN MONTYS HANDYMAN
Authors: Monteski Ammar Rafi , Nurcaya I Nyoman
Published: February 2025

Kelancaran proses produksi perusahaan diperlukan untuk peningkatan efektifitas dan efisiensi operasional perusahaan. Hal tersebut akan berakibat pada output yang dihasilkan perusahaan. Terdapat banyak faktor yang mempengaruhi kelancaran proses produksi diantaranya yaitu layout dan penjadwalan produksi. Penelitian ini bertujuan untuk menjelaskan pengaruh layout dan penjadwalan produksi terhadap kelancaran proses produksi. Layout dan penjadwalan produksi akan secara bersama-sama mempengaruhi kelancaran proses produksi. Lokasi penelitian dilakukan di workshop perusahaan Montys Handyman dengan jumlah populasi dan sampel yang digunakan sebanyak 42 orang karyawan. Pengumpulan data dilakukan menggunakan alat bantu kuesioner yang telah teruji validitas dan reliabilitasnya. Teknik analisis data yang digunakan pada penelitian ini yaitu Analisis Statistik Deskriptif dan Analisis Regresi Linear Berganda. Hasil menunjukkan bahwa layout dan penjadwalan produksi berpengaruh secara positif dan signifikan terhadap kelancaran proses produksi. Implikasi yang dapat diambil pada penelitian ini secara teoritis selaras dengan penelitian-penelitian sebelumnya, dan dapat menjadi tambahan wawasan, refrensi, dan informasi yang mendukung bagi penelitian selanjutnya yang berhubungan dengan pengaruh layout dan penjadwalan produksi terhadap kelancaran proses produksi. Secara praktis pihak perusahaan Montys Handyman dapat meningkatkan fleksibilitas dengan melakukan penyusunan ulang layout, serta meningkatkan ketepatan tersedianya bahan baku dengan cara melakukan komunikasi lebih kepada supplier yang berkaitan dengan bahan baku produksi.
Kata kunci: Layout; Penjadwalan; Proses Produksi
NILAI HEDONIS DAN NILAI UTILITARIAN TERHADAP KEPUASAN PELANGGAN SERTA DAMPAKNYA TERHADAP NIAT MEMBELI KEMBALI
Authors: Seminari Ni Ketut , Rastini Ni Made
Published: February 2025

Angkringan businesses are widely spread both in Denpasar and in the tourist area of Kuta, Badung. A simple business, but popular as a hangout place for young people. The aim of this research is to determine the influence of hedonic value and utilitarian value on consumer satisfaction, as well as their influence on repurchase intentions. The number of respondents in the research was 100 respondents. Research data was analyzed using SEM (Structural Equation Modeling) analysis. The research results show that hedonic value, utilitarian value, and consumer satisfaction have a positive and significant effect on repurchase intentions. Consumer satisfaction is able to mediate hedonic value and utilitarian value on repurchase intentions. Keywords: Hedonic Value; Utilitarian Value; Consumer Satisfaction; And Niat membeli kembali
Hubungan Asupan Gizi dan Pola Asuh Terhadap Kejadian Stunting Pada Balita Usia 2-5 Tahun
Authors: Rahmawati Dwi , Astria Niki
Published: February 2025

Latar Belakang: Stunting, yang dikenal sebagai balita pendek adalah salah satu masalah gizi yang dialami balita di dunia saat ini dan berdampak pada pertumbuhan dan perkembangan intelektual anak. Tujuan: Mengetahui bagaimana pola asuh dan asupan gizi berkorelasi dengan kasus stunting pada balita berusia 2-5 tahun. Metode: Penelitian kuantitatif analitik dengan desain cross-sectional digunakan. Sampling total terdiri dari 55 balita berusia 2-5 tahun yang diambil. Pemeriksaan antropometri tinggi badan dan kuesioner digunakan untuk mengumpulkan data. SPSS digunakan untuk menganalisis data univariat dan bivariat. Hasil: Penelitian menunjukkan bahwa dari 30 (54,5 %) balita yang mengalami stunting 23 (41,8%) memiliki asupan gizi yang buruk. Untuk 18 (32,7 %) balita yang memiliki pola asuh yang buruk, uji statistik menemukan nilai p 0,072 (≥0,05), yang menunjukkan bahwa tidak ada hubungan antara pola asuh dan asupan gizi terhadap stunting pada balita berusia 2-5 tahun di wilayah kerja Puskesmas Muara Madras. Simpulan: terdapat korelasi antara stunting dan asupan gizi, tetapi tidak ada korelasi antara gaya pengasuhan dengan stunting pada anak usia dua hingga lima tahun di wilayah kerja Puskesmas Muara Madras.
Hubungan Kepatuhan Kunjungan Antenatal Care dengan Cara Persalinan di Puskesmas Sukaindah Kabupaten Bekasi
Authors: Sunarto Agus , Fadlina Filda , Agusfar Achmad Zani , Wahyuni Tri
Published: February 2025

Latar Belakang: Persalinan normal adalah proses persalinan melalui vagina dan persalinan Caesar atau Sectio caesarea (SC) yaitu proses mengeluarkan janin melalui irisan pada dinding perut dan rahim. Menurut World Health Organization (WHO) persalinan normal terdapat (79 %) sedangkan persalinan SC terdapat (21.1%) persalinan di Dunia dari (94.5%) kelahiran hidup. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan antara kepatuhan kunjungan ANC dengan cara persalinan di Puskesmas Sukaindah. Metode: Penelitian dengan desain kuantitatif analitik cross-sectional menggunakan metode observasional. Sampel dalam penelitian ini adalah total sampling sebesar 375 responden yang memenuhi kriteria inklusi dan eksklusi . Analisis data secara Chi-square dengan menggunakan SPSS. Hasil: Hasil penelitian menunjukkan angka tertinggi dalam distribusi kepatuhan kunjungan ANC adalah ibu hamil yang tidak patuh kunjungan ANC yaitu sebanyak (53,1%), persentase ibu dengan persalinan spontan atau normal lebih tinggi dibanding ibu bersalin secara sectio caesarea (SC) yaitu sebanyak (67,2%), terdapat (79,7%) ibu yang hamil dalam usia yang aman (20 – 35 tahun), angka paritas tertinggi yaitu pada ibu dengan paritas 2 – 3 kali (74,4%),  etiologi terbanyak yang menyebabkan ibu rujuk bersalin adalah ketuban pecah dini yaitu sebanyak (39,0%). Hasil kepatuhan kunjungan ANC dengan cara persalinan didapatkan nilai p-value 0,000 ( 0,05). Simpulan: Terdapat hubungan yang signifikan antara kepatuhan kunjungan ANC dengan cara persalinan di Puskesmas Sukaindah. Ibu hamil yang patuh mengikuti kunjungan ANC lebih cenderung untuk melahirkan secara normal dibandingkan dengan ibu hamil yang tidak patuh mengikuti kunjungan ANC. Ibu yang tidak patuh melakukan kunjungan ANC lebih berisiko 3,467 kali untuk bersalin secara sectio caesarea.
Passive leg raising test – optimal methodology. A systematic review and meta-analysis (literature review)
Authors: Berikashvili L. B. , Kuznetsov I. V. , Polyakov P. A. , Yadgarov M. Ya. , Ryzhkov P. V. , Yakovlev A. A. , Korolenok E. M. , Likhvantsev V. V.
Published: February 2025

Introduction. The passive leg raising (PLR test) test is a widely used diagnostic test for assessing fluid responsiveness. However, there is no generally accepted methodology describing the details of its implementation.

The objective was to establish criteria for conducting the PLR test based on the diagnostic accuracy of various variations.

Materials and methods. A systematic review and meta-analysis included prospective cohort studies that evaluated the diagnostic accuracy of different PLR test variations. The primary endpoint was the area under the ROC curve (AUROC). The search was conducted up to March 2024 and included «snowball» method. The covariate influence was assessed via univariate meta-regression. The risk of bias was evaluated using QUADAS-2, and evidence certainty was assessed with GRADE.

Results. The meta-analysis included 33 prospective cohort studies, 1,607 critically ill patients The AUROC for the PLR test was 0.882 [0.849; 0.916] (moderate certainty of evidence). Transthoracic and transesophageal echocardiography, transpulmonary thermodilution, and pulse contour analysis showed comparable results for assessing cardiac hemodynamics during PLR test, p = 0.253 (moderate certainty of evidence). Evaluating hemodynamic changes within the first two minutes of the PLR test increased diagnostic accuracy (high certainty of evidence). The starting body position (low Fowler’s position or supine) during the PLR test did not impact diagnostic accuracy (low certainty of evidence). Baseline covariates (age and gender) had no effect on diagnostic accuracy of the PLR test in critically ill patients (high certainty of evidence).

Conclusion. For assessing fluid responsiveness in critically ill patients, the PLR test should include intracardiac hemodynamic assessment within two minutes using any common method. Low Fowler’s position is preferable starting position of the body for PLR test.
Perbandingan Potensi Anti Bakteri Ekstrak Etanol Jahe Merah, Jahe Putih, dan Bangle Terhadap Pertumbuhan Lactobacillus Reuteri Secara In Vitro
Authors: Hujjatusnaini Naini , Astuti Muh Amin  , Dahliyanti  , Purwita Sari  , Nur Khusna
Published: February 2025

Jahe diketahui bermanfaat untuk mengatasi infeksi bakteri pada mulut seperti pada gusi, infeksi padasaluran pernapasan juga bisa mengatasi masalah pencernaan. Agen antibakteri yang terkandung dalamjahe merah (Zingiber officinale var. Runrum), jahe putih (Zingiber officinale var. amarum) dan bangle(Zingiber montanum) dapat melawan bakteri jahat, seperti lactobacillus reuteri. Penelitian ini mengujiperbandingan potensi anti bakteri sedian ekstrak etanol jahe merah, jahe putih, dan bangle terhadappertumbuhan bakteri lactobacillus reuteri. penelitian ini merupakan penelitian eksperimen, terhadapperbandingan potensi antibakteri Jahe merah, jahe putih dan bangle. Terhadap bakteri LactobacillusReuteri dengan diberikan konsentrasi Jahe putih 30%, 40%, 50%, 60%, bangle 4%, 6%, 8%, 10%, 12%,dan Jahe merah 10%, 15%, 20%, 25%, 30% kontrol (+) Yakult 70%, 80%, 90% dan kontrol (-) aquadesdengan selalu memperhatikan kecepatan tumbuhnya bakteri secara spesifik dengan waktu generasi selama3x24 jam inkubasi.Hasil penelitian ini menunjukkan bahwa antibakteri pada control negatif terhadapLactobacillus reuteri lebih efektif dibandingkan dengan jahe merah, jahe putih dan bangle. Pada ekstrakjahe merah konsentrasi 20%, pada ekstrak jahe putih 50% dan pada ekstrak bangle dengan konsentrasi 4%.adalah perbandingan yang paling efektif di lihat dari zona hambat yang terbentuk
Pengaruh Penggunaan Modul Ekologi Terhadap Keterampilan Komunikasi, Kognitif, dan Sikap Mahasiswa Melalui Pembelajaran Berbasis Masalah
Authors: Ginanjar Gigin , Rahayu Maya
Published: February 2025

Pembelajaran yang dilakukan di dalam perkuliahan sangat memerlukan beragam sumber belajar gunameningkatkan kemampuan mahasiswa menjadi lebih baik. selama ini perkuliahan biasanya pembelajaranhanya menggunakan sumber belajar yang tidak banyak variasinya dan cenderung menggunakan satusumber saja, sehingga hasil belajar mahasiswa tidak maksimal. Penelitian ini dilakukan dengan tujuanuntuk meningkatkan hasil belajar mahasiswa menjadi semakin baik khususnya pada keterampilankomunikasi, kognitif dan sikap di Universitas Bina Bangsa. Penerapan modul dalam pembelajarandilakukan dengan rancangan eksperimental semua (quasi eksperiment) kemudian hasilnya dianalisis secaradeksiptif dengan uji statistik anakova menggunakan aplikasi SPSS. Hasil penelitian menunjukan bahwaketerampilan komunikasi, kemampuan kognitif, dan sikap mahasiswa mengalami peningkatan.Berdasarkan uji statistik yang didapat dengan signifikansi 0,000 lebih kecil dari alpha 0,05 (α<0,005)sehingga dapat disimpulkan ada perbedaan pencapaian keterampilan komunikasi, kognitif, dan sikapmahasiswa antara di kelas kontrol dengan perlakuan. Hanya saja berdasarkan nilai gain skor, penggunanmodul ajar berbasis masalah terhadap keterampilan komunikasi (0,17) dan sikap mahasiswa (0,24) beradapada rentang ≤0,3 yang berarti efektifitasnya rendah, sementara pada aspek kognitif (0,54) berada padarentang 0,3 ≤ g ≤ 7 yang nilai keefektifaannya sedang.
Inflammatory myofibroblastic tumors in children: clinical characteristics and treatment outcomes with a focus on targeted therapies
Authors: Yıldırım Ülkü Miray , Kebudi Rejin , Zülfikar Bülent , Bilgiç Bilge
Published: February 2025

Background. Inflammatory myofibroblastic tumors (IMTs) are rare neoplasms in children. Traditionally, surgical resection has been the primary treatment modality with limited efficacy reported for conventional chemotherapy and radiation therapy. Recently, targeted therapies have emerged as potential options for selected cases. This study aimed to evaluate the demographic, clinical, laboratory, and radiological characteristics, as well as treatment outcomes, in children diagnosed with IMTs.
Methods. This study involved a retrospective review of medical records for eight children diagnosed with IMTs between 1990 and 2022. We collected demographic, clinical, laboratory, and radiological data, as well as treatment outcomes. Data on tumor characteristics, surgical procedures, and chemotherapy or targeted therapy treatments were extracted.
Results. The mean age at diagnosis was 9 years. None presented with metastatic disease at the time of diagnosis. Anaplastic lymphoma kinase (ALK) positivity was identified in tumor tissue from five patients. Among the six patients who underwent surgical resection, three achieved negative surgical margins. Of the three patients with positive surgical margins, one underwent re-resection, local and metastatic recurrences were noted in another, and one was started on crizotinib. A patient with an inoperable tumor at diagnosis was initiated on crizotinib and achieved complete remission. Ceritinib was administered to a patient with YWHAE-ROS fusion, resulting in more than 90% reduction in tumor volume. The median follow-up time was 67.5 months. The five-year overall survival and event-free survival rates for the cohort were 85.7% and 72.9%, respectively.
Conclusions. While surgical resection remains the cornerstone of treatment for IMTs, favorable outcomes can be achieved with chemotherapy and targeted therapies in selected cases. Increasing the utilization of targeted therapies may be beneficial, particularly through molecular studies aimed at minimizing the side effects associated with conventional chemotherapy.
Effects of Hormone Therapy on the Uterus: A Review
Authors:   The Mount Sinai Icahn School Of Medicine, Deligdisch Liane
Published: February 2025

Hormonal therapy is presently widely used for numerous health issues of the female population. Oral contraceptives, fertility stimulation, treatment of menopausal symptoms and management of benign and malignant neoplasms of the female genital tract with hormones are highly effective in most cases.
What Happened at the Tepebaşı Theater?
Authors: Yuce Can
Published: February 2025

In 1956, a group of young Turkish poets and writers staged a public protest at Istanbul’s Tepebaşı Drama Theater. The protest against the literary establishment was later portrayed as a communist insurgence by the mainstream press. This article discusses the significance of the protest and its aftermath, and explores the importance of the Cold War context in understanding its long-term consequences regarding Turkish cultural and political history. While the cultural Cold War studies mostly focus on the centre, the competition between the United States and the Soviet Union, and tend to reduce the Cold War’s cultural impact on the periphery to propaganda wars, this article argues that the Cold War’s repercussions on peripheral cultures are more nuanced than the conventional narratives. The public reception of the Tepebaşı Drama Theater protest is an illustrious example of the tensions between culture and ideology on the periphery during the Cold War era.
Penerapan Metode Analytical Hierarchy Process dan Simple Additive Weighting Dalam Penentukan Lokasi Pembuatan Rumah Burung Walet
Authors: Nur Seftiani , Yulianto Fendy , Rahim Abdul
Published: February 2025

Burung walet adalah penghuni khas wilayah tropis dan lembab, yang hidup berkelompok dan membangun sarang dari air liur di gua atau tempat lembab dan gelap. Sarang burung walet memiliki banyak manfaat kesehatan, termasuk mempercepat regenerasi sel, memperkuat sistem kekebalan tubuh, dan menjaga Kesehatan pencernaan, sehingga memiliki nilai jual yang tinggi. Oleh karena itu, budidaya sarang burung walet memerlukan perencanaan yang cermat terkait penentuan lokasi yang tepat untuk memaksimalkan hasil. Penentuan lokasi yang tidak tepat dapat menyebabkan kerugian akibat Gedung walet yang tidak ditempati. Untuk membantu petani walet dalam menentukan lokasi yang tepat, berbagai metode, termasuk pengamatan langsung dan penggunaan aplikasi sistem cerdas dapat digunakan. Sistem cerdas seperti Sistem Pendukung Keputusan (SPK) dapat memberikan rekomendasi menggunakan metode AHP-SAW. Metode AHP memberikan kontribusi dalam pengambilan keputusan dengan mempertimbangakan kriteria yang telah ditentukan, sementara metode SAW digunakan untuk proses perangkingan. Hasil pengujian metode AHP menunjukan akurasi sebesar 63%, sementara kombinasi metode AHP-SAW menunjukan akurasi sebesar 73%. Dengan demikian, kombinasi metode AHP-SAW diharapkan dapat memberikan rekomendasi lokasi yang lebih tepat untuk pembuatan rumah burung walet, sehingga meningkatkan efisien dan hasil budidaya.
Penerapan Deep Learning dengan Mekanisme Attention untuk Meningkatkan Performa Segmentasi Liver dan Tumor pada Citra CT Menggunakan ResUnet
Authors: Eka Putra Zaky Dafalas , Utomo Danang Wahyu
Published: February 2025

Kanker hati merupakan salah satu penyebab kematian paling tinggi di dunia. Dalam mendeteksi kelainan pada hati perlu dilakukan segmentasi untuk mengambil bagian dari hati yang mengalami gangguan. Namun, metode segmentasi manual memakan waktu dan rawan kesalahan. Selain itu, metode tradisional juga sering kali kesulitan menangani variasi bentuk, ukuran, dan tekstur tumor, serta kualitas citra yang heterogen, sehingga mengurangi akurasi segmentasi. Oleh karena itu, penelitian ini mengusulkan penerapan model segmentasi menggunakan mekanisme Attention ResUnet, yang menggabungkan arsitektur residual dan konvolusi berbasis skip connection, ditingkatkan dengan attention untuk meningkatkan akurasi deteksi tumor. ResUnet dirancang untuk meningkatkan akurasi dan stabilitas segmentasi tumor dengan mengatasi masalah vanishing gradient dan meningkatkan kemampuan deteksi fitur kompleks. Dataset citra CT yang digunakan dalam penelitian ini dipra-pemroses melalui windowing untuk fokus pada rentang intensitas organ hati dan menghilangkan organ yang tidak penting. Hasil penelitian menunjukkan bahwa model Residual Unet dengan mekanisme Attention mampu meningkatkan performa segmentasi gambar CT hati dan tumor secara signifikan, mencapai akurasi 99.54% dan nilai Dice sebesar 95% pada segmentasi liver, serta akurasi 99.5% dan nilai Dice sebesar 90% pada segmentasi tumor. Penambahan modul Residual dan Attention secara efektif membantu model menangkap fitur yang relevan, khususnya dalam menangani lesi kompleks dan batas kabur, yang sering menjadi tantangan dalam segmentasi citra medis.
Estrategias de Bioremediación para tratamiento de Contaminantes Emergentes: una visión desde la Fito-remediación
Authors: Peña-Salamanca Enrique J. , Ramírez-Lamus Juan C. , Cabrera-Arana Hernán M. , Jiménez-Bambague Eliana M. , Madera-Parra Carlos A.
Published: February 2025

Introducción: Los contaminantes emergentes (CEs) son una amplia y creciente categoría de sustancias encontradas en el ambiente que solo recién se reconoce como significativos contaminantes del agua. La inhabilidad de las plantas de tratamiento de aguas residuales (PTAR) para remover efectivamente CEs hace necesarios métodos de tratamientos alternativos y ambientalmente amigables.
Objetivo: El objetivo de la revisión es explorar estrategias de bioremediación para contaminantes emergentes usando humedales construidos y el papel de las plantas en la fitoremediación de aguas servidas. Metodología: Considero una revisión bibliográfica usando las bases de datos electrónicas de la biblioteca de la Universidad del Valle, específicamente SCOPUS y ScienceDirect (Elsevier). La búsqueda usó palabras claves como “Contaminantes Emergentes”, “Humedales Construidos” y de “Plantas Tropicales en Fitoremediación” y se priorizaron las publicaciones de los últimos 3 años. Resultados: La remoción de CEs en HCs involucra complejos procesos físicos, químicos y biológicos, los que son influenciados por el diseño y parámetros operacionales del sistema. Los HC varían significativamente en diseño, con las configuraciones que incluyen sistemas de flujo superficial (FS) y subsuperficial (FSS), así como flujo horizontal (FHSS) y vertical (FVSS). Las configuraciones difieren en tipo de medio, profundidad y en la eficiencia del tratamiento. Conclusiones: Esta revisión examina la presencia de CEs en ambientes acuáticos y explora el uso de las plantas en HC como estrategias de fitorremediación. Los hallazgos indican que los HCs son una alternativa sostenible y efectiva con mecanismos de remoción claves -incluyendo biodegradación, adsorción de sustrato y ingreso de macrofita- jugando un papel crucial en eliminar CEs recalcitrantes. El diseño y condiciones operacionales de los HCs impactan significativamente la eficiencia de fitorremediacion.
POLÍTICAS DE INCENTIVO AO ALEITAMENTO MATERNO EM HOSPITAIS E MATERNIDADES: UMA REVISÃO SISTEMÁTICA
Authors: Costa Ísis Bheatriz Nunes Pessoa , Barros Monique Kelly Duarte Lopes
Published: February 2025

Introdução: O Aleitamento Materno, especialmente nos primeiros seis meses de vida, é um fator primordial para o crescimento e desenvolvimento do Recém-Nascido, contribuindo para o vínculo afetivo entre mãe e filho, favorecendo o processo imunológico e psicológico. A prevalência mundial de bebês amamentados exclusivamente é de apenas 38%. No Brasil, 75% começam a ser amamentados desde o nascimento, diminuindo aos três meses de vida pela introdução de fórmulas infantis, apontando a importância de ações que orientem, apoiem e protejam o Aleitamento Materno Exclusivo e a sua duração para a melhores índices. Objetivo: Verificar quais as políticas de incentivo ao aleitamento materno adotadas nos hospitais e maternidades. Método: Trata-se de uma revisão sistemática, seguindo as recomendações do método PRISMA. A pergunta norteadora formulada a partir da estratégia PICO foi: “Quais as políticas de incentivo ao aleitamento materno adotadas nos hospitais e maternidades?”. Foram consultadas as bases de dados PUBMED, MEDLINE, LILACS e SCiELO, entre janeiro a março de 2023. Para as buscas, foram combinados os descritores controlados com os operadores booleanos AND e OR, sendo incluídos somente artigos em língua portuguesa, devido a proposta do estudo em pesquisar as políticas nacionais de incentivo ao AM. Resultados: Foram selecionados 16 artigos, onde destes apenas 6 adotaram políticas de incentivo associados ao aumento das taxas de AME intra-hospitalar e na alta. A Iniciativa Hospital Amigo da Criança foi a estratégia mais presente nos estudos selecionados quanto ao incentivo do aleitamento materno. Conclusão: A IHAC e Método Canguru/Mãe Canguru foram as políticas adotadas por os hospitais e maternidades para o incentivo ao AM identificados nesta revisão sistemática.
Chrystus tu i teraz. Charakterystyka chrystologii protestanckiej i postulaty dla chrystologii katolickiej w ujęciu Alfonsa Nossola
Authors: Lorek Piotr
Published: February 2025

Praca stawia sobie za zadanie przybliżenie refleksji chrystologicznej Alfonsa Nossola (ur. 1932). Znany z zasług na rzecz ekumenizmu duchowny Kościoła rzymskokatolickiego podjął się w swojej pracy naukowej zadania systematyzacji myśli ewangelickiej. Chcąc przybliżyć niektóre wyniki jego aktywności akademickiej powołujemy się na wybrane jego prace. Nossol opracowuje teologicznie myśl protestancką wyszczególniając pięć formalnych i pięć materialnych składowych nauki reformacyjnej. W ten sposób wskazuje na chrystologię jako węzłowy punkt myśli reformacyjnej. Nossol podejmuje się także uchwycenia specyfiki samej chrystologii protestanckiej wydobywając jej sześć charakterystycznych cech. Wreszcie, dostrzegając obecny kryzys chrystologii i inspirując się osiągnięciami chrystologii protestanckiej wysuwa postulaty pod opracowanie integralnej chrystologii katolickiej. Jej celem jest zachowanie ortodoksji i uwzględnienie współczesnych badań naukowych. W końcu Nossol stawia fundamentalne pytanie o to, kim jest dzisiaj Jezus Chrystus. To pytanie o tu i teraz Chrystusa wciąż pozostaje aktualne. Wymaga wysiłku ekumenicznego, który nie tylko uwzględni Sitz im Leben Jezusa, ale także usytuowania samego teologia podejmującego się refleksji chrystologicznej.
Hermeneutyka liturgii: nowy dyskurs teologii i pułap istnienia
Authors: Michalczuk Witali
Published: February 2025

Artykuł jest poświęcony myśli teologicznej ks. Jerzego Klingera, która wynika z doświadczenia liturgicznego. Liturgia jest wyjściową intuicją tego wielkiego prawosławnego teologa. W ramach liturgii nie tylko mistyka eucharystii, ale i sama formuła sztuki staje się paradygmatem myślenia teologicznego. Realizm liturgiczny jako formuła ontologiczna eucharystii i poetyki sztuki w liturgii określa w myśli ks. Klingera wizję Kościoła i dróg jedności podzielonego chrześcijaństwa. Liturgiczną intuicja zostaje przełożona na doświadczenie poezji, która dla tego teologa-poety była nieodmiennie nowym sposobem istnienia i rozumienia.
Krwią radosnego serca pisane. O poezji ks. Jerzego Klingera
Authors: Janocha Michał
Published: February 2025

Jerzy Klinger (1918–1976), wybitny polski teolog prawosławny, był także ciekawym poetą. W ostatnim, czwartym tomie jego Dzieł zebranych, opracowanych przez ks. Henryka Paprockiego (Kraków: Tyniec Wydawnictwo Benedyktynów 2023), znalazły się polskie i rosyjskie wiersze ks. Jerzego Klingera. Wiersze polskie zostały wydane po raz pierwszy, niemal pół wieku po śmierci Autora, co w historii współczesnej poezji polskiej pozostaje zjawiskiem bezprecedensowym. Niniejszy artykuł podejmuje wstępną próbę odnalezienia w nich wątków autobiografii duchowej i intelektualnej. Kolejne części artykułu przywołują wybrane obszary, tematy i źródła jego poetyckiej twórczości: dzieciństwo, milczenie, romantyzm i klasyczność, podróże.