bluuebunny/crossref_metadata_2025 huggingface dataset:
Oncological and surgical characteristics of patients with ovarian cancer diagnosed in the main multidisciplinary hospital in Romania
Authors:   Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania, Potorac Alina , Baros Alexandru ,   Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Turcan Natalia ,   Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania, Secara Diana ,   Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Edu Antoine ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Obstetrics and Gynecology, “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania, Mehedintu Claudia ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Department of Obstetrics and Gynecology, “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania, Carp-Veliscu Andreea ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Andreescu Cristina Veronica ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Cirstoiu Monica Mihaela ,   Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: June 2022

Malignant ovarian neoplasms represent a public health issue, being one of the most frequent cancers among women, exhibiting the highest mortality rate. The general purpose of this study lays in the analysis of the metastasizing potential of malignant ovarian neoplasms, the correlation between the histological subtype and the genesis of the metastasis. We present an observational retrospective study spanning over 2 years, between 2018-2019, on 30 admitted patients who were treated for malignant ovarian neoplasms in the department of Obstetrics and Gynecology of Bucharest Emergency University Hospital. The most frequent histopathological subtype encountered in our study has been the high grade serous ovarian carcinoma 46,67%, with 30% presenting poorly differentiated neoplasms (G3), therefore having poor prognosis. A considerable number of patients 56,67% presented ascites (among which 43,33% of patients also exhibited peritoneal carcinomatosis, direct dissemination representing the main metastasizing pathway of malignant ovarian neoplasms in the patients included in our study. From our study we can conclude that patients with ovarian malignant neoplasms are diagnosed in an advanced stage of the disease, when metastasis are already present, with a poor prognosis. This is mainly due to the lack of regular gynecological check-ups in menopausal women and because it is considered that once past the fertile age the gynecological examination no longer represents a necessity.
Management of placenta percreta – case report and clinic experience
Authors:   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania, Secara Diana Cristina ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Mehedintu Claudia ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania, Carp-Veliscu Andreea ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Edu Antoine ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Teodor Oana Mihaela ,   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania, Negru Alice ,   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania, Gradinaru-Fometescu Delia ,   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania, Constantin Traian Vasile ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   “Prof. Dr. Theodor Burghele” Clinical Hospital, Bucharest, Romania, Uzunov Ana Veronica ,   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania,   Doctoral School, University of Medicine and Pharmacy, Bucharest, Romania, Bratila Elvira ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Cirstoiu Monica Mihaela ,   Department of Obstetrics and Gynaecology, University Emergency Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: June 2022

The incidence of placenta percreta is currently increasing. The treatment strategies are not clearly defined as there are a lot of inconsistencies in the literature regarding severity criteria. This pathology has a high risk for massive hemorrhage, therefore it is very challenging to agree on a standardized management. The therapeutic approaches include expectant management with placenta left in situ, conservative management and radical treatment. Cesarean hysterectomy currently represents the approach of choice for this condition, ideally performed by a multidisciplinary team. Conservative alternatives have been proposed to reduce maternal morbidity and maintain future fertility. The expectant management has benefits on reducing uterine perfusion and blood loss, useful in case of bladder or parametrial invasion. Potential late complications of placenta percreta left in situ often require further emergency surgery. Delayed hysterectomy has the aim to overcome these difficulties, but the reported outcomes are still contradictory. For these reasons, the most recent recommendation is not to perform a second elective surgery in a hemodynamically stable patient. In this paper we present the late complications of a case treated by expectative approach and the overall management in our clinic for the last five years with placenta accreta spectrum disorders.
Obesity and pregnancy
Authors:   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania, Melestean-Bratu Madalina-Ioana , Edu Antoine ,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Bujor Mihaela ,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ionescu Oana Maria ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Isopescu Florin ,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Mateescu Radu-Nicolae ,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Carp-Veliscu Andreea ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Dumitrascu Mihai ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Sandru Florica ,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Mehedintu Claudia ,   “Nicolae Malaxa” Clinical Hospital, Bucharest, Romania,   “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: June 2022

Obesity and overweight, the most common metabolic disorders, have an increased incidence among women of reproductive age and represent major risk factors in obstetrics. Maternal obesity predisposes to multiple maternal and fetal complications, like pregnancy-induced hypertension, gestational diabetes, thromboembolic complications, recurrent miscarriages, stillbirth, macrosomia, congenital abnormalities.
Toward RNA Life on Early Earth: From Atmospheric HCN to Biomolecule Production in Warm Little Ponds
Authors: Pearce Ben K. D. , Molaverdikhani Karan , Pudritz Ralph E. , Henning Thomas , Cerrillo Kaitlin E.
Published: June 2022

The origin of life on Earth involves the early appearance of an information-containing molecule such as RNA. The basic building blocks of RNA could have been delivered by carbon-rich meteorites or produced in situ by processes beginning with the synthesis of hydrogen cyanide (HCN) in the early Earth’s atmosphere. Here, we construct a robust physical and nonequilibrium chemical model of the early Earth’s atmosphere. The atmosphere is supplied with hydrogen from impact degassing of meteorites, water evaporated from the oceans, carbon dioxide from volcanoes, and methane from undersea hydrothermal vents, and in it lightning and external UV-driven chemistry produce HCN. This allows us to calculate the rain-out of HCN into warm little ponds (WLPs). We then use a comprehensive numerical model of sources and sinks to compute the resulting abundances of nucleobases, ribose, and nucleotide precursors such as 2-aminooxazole resulting from aqueous and UV-driven chemistry within them. We find that 4.4 billion years ago the limit of adenine concentrations in ponds for habitable surfaces is 0.05 μM in the absence of seepage. Meteorite delivery of adenine to WLPs can provide boosts in concentration by 2–3 orders of magnitude, but these boosts deplete within months by UV photodissociation, seepage, and hydrolysis. The early evolution of the atmosphere is dominated by the decrease in hydrogen due to falling impact rates and atmospheric escape, and the rise of oxygenated species such as OH from H2O photolysis. The source of HCN is predominantly from UV radiation rather than lightning. Our work points to an early origin of RNA on Earth within ∼200 Myr of the Moon-forming impact.
Pulse Profile Variations Associated with Two Glitches of PSR B1822–09
Authors: Liu Jie , Wang Hong-Guang , Shen Zhi-Qiang , Yan Zhen , Tong Hao , Huang Zhi-Peng , Zhao Ru-Shuang
Published: June 2022

We reported two new glitches of PSR B1822−09 that were detected at the Shanghai Tian Ma Radio Telescope. The glitches occurred around MJD 58,025 and 58,474.5, respectively. The shapes of the integrated mean pulse profiles in both the radio-bright (B-mode) and the radio-quiet (Q-mode) modes changed after two glitches. Such changes are probably related to the trigger mechanisms of the glitches. According to the Gaussian fitting to the integrated mean pulse profiles, variations of the integrated mean pulse profiles can be attributed to variations of the Gaussian components. The fitting also indicates that there may be changes in only a part of the Gaussian components after glitches. We proposed an interpretation of the relation between the precursor and the interpulse of PSR B1822−09 according to variations of Gaussian components. We analyzed the cumulative distributions of the glitch sizes and the waiting times of all 14 glitches of PSR B1822−09. The cumulative distribution of the glitch sizes can be fitted well by a power law with an index α of 0.985 ± 0.005. The cumulative distribution of the waiting times follows a Poisson model with a mean waiting time λ of 466 ± 66 days. The correlation coefficient between the waiting times and the sizes of the corresponding preceding glitches is 0.906. In contrast, there is no apparent correlation between the waiting times and the sizes of the corresponding trailing glitches.
A new species of the genus Hypocharassus Mik (Diptera, Dolichopodidae) from Korea
Authors: Kim Young-Kun , Suh Sang Jae
Published: June 2022

The genus Hypocharassus Mik, 1879 has only been recorded in the Nearctic and Oriental regions and, to date, it contains four known species.

Hypocharassus cavitarsussp. n. is described from Korea. This is the first record of this genus in the Palearctic Region. A description of the new species and a key to the Hypocharassus species are presented herein.
Une passion exigeante. Gerhard Mauz et la justice
Authors: Pivert Benoît
Published: June 2022

Gerhard Mauz (1925-2003) fut chroniqueur judiciaire au Spiegel de 1964 à 1990. Dans le domaine de la chronique judiciaire, il fut à la République fédérale ce que Paul Schlesinger avait été pour la République de Weimar : un observateur impitoyable des mœurs judiciaires, un explorateur audacieux des arcanes du psychisme et un journaliste doué d’un indéniable talent littéraire. Les chroniques de G. Mauz ont été réunies dans deux volumes, Die Gerechten und die Gerichteten (1968) et Die großen Prozesse der Bundesrepublik Deutschland (2015). Je montre dans cet article que, si G. Mauz, satisfait aux exigences de ce genre journalistique qu’est la chronique judiciaire, nombre de ses articles se lisent comme de véritables nouvelles psychologiques. Certains constituent des documents sociologiques, d’autres présentent un intérêt pour l’historien. Dans bien des chroniques, Mauz égratigne la justice, mais c’est surtout dans deux volumes d’essais qu’il s’en prend à l’institution judiciaire : Das Spiel von Schuld und Sühne. Die Zukunft der Strafjustiz (1975) et Die Justiz vor Gericht (1990). Il y fait le procès des acteurs de la justice et livre une réflexion sur les zones d’ombre du code pénal et les fondements de la justice pénale. À la mort de Mauz en 2003, Rudolf Augstein saluera une contribution sans équivalent à la culture politique de la République fédérale.
Sculpture et paysage dans le monde grec à l’époque hellénistique première partie : les III e et II e s. av. J.‑C.
Authors: Biard Guillaume
Published: June 2022

La haute époque hellénistique ouvre une phase de réflexion intense sur les rapports entre sculpture et paysage, qui se développe dans trois directions principales : l’artiste intervient parfois directement sur le paysage, modifiant l’apparence d’un site ; il peut également insérer une œuvre dans un paysage pré-existant, dont il modifie la signification ; il peut enfin représenter en sculpture un paysage. Particulièrement importantes à Rhodes, ces recherches répondent à diverses attentes esthétiques : s’il représente d’une manière générale l’ordre du monde et de la société, le paysage est parfois le support d’une narration complexe ou d’une réflexion sur la création.
Une série de faux miroirs étrusques. À propos d’une demande qu’Olof August Danielsson ne fit pas à Ferdinand de Saussure
Authors: Briquel Dominique , Muller Jean-Claude , Mejía Quijano Claudia
Published: June 2022

Un échange de correspondance eut lieu en 1906 entre le linguiste genevois F. de Saussure et l’étruscologue suédois O. A. Danielsson. Dans une version préparatoire d’une lettre de Danielsson à Saussure, qui ne fut pas envoyée sous cette forme et est conservée aujourd’hui à l’université d’Uppsala, Danielsson voulait demander à Saussure d’examiner trois objets du musée Fol de Genève portant des inscriptions étrusques. L’un d’entre eux, un miroir avec la représentation du rapt de Thétis par Pélée, était un faux, ce dont on ne s’était pas avisé à l’époque. Cet objet appartient à une abondante série de faux, apparue à Pérouse en 1865, dont de nombreux exemplaires existent dans des collections actuelles, sans que leur caractère de faux ait été toujours reconnu.
Éditorial – Les services urbains en réseaux au prisme des interdépendances : portées et limites d’une notion de sciences sociales
Authors: Caillaud Kevin , Nessi Hélène , Rulleau Bénédicte
Published: June 2022

Dans le domaine des services urbains en réseaux, la question des « interdépendances » – entendues globalement comme des relations mutuelles, produisant des effets de réciprocité – est longtemps restée secondaire. Elle n’intervenait de manière explicite le plus souvent que pour analyser la vulnérabilité des services et des réseaux et les effets cascade engendrés lors de crises. Néanmoins, depuis une dizaine d’années, cette notion connaît une acuité accrue, notamment sous l’effet des changements globaux et du développement des approches transversales en matière d’action publique. Mais que signifie concrètement cette notion d’interdépendance ? Comment se traduit-elle empiriquement ? Quel(s) intérêt(s) présente-t-elle d’un point de vue heuristique ? Et quels impératifs méthodologiques convoque-t-elle ? C’est à ces questions qu’ambitionne de répondre ce chapitre introductif du numéro spécial de la revue Flux , en ouvrant un espace de dialogue et de réflexion au croisement d’une exploration épistémologique de la notion en sciences humaines et sociales et de six contributions originales. Précisément, ce chapitre permet de clarifier le sens et le contenu de la notion, en insistant sur l’analyse de la « matière » et des formes d’interdépendance.
Des tuyaux qui comptent. Tournant patrimonial et renégociation des relations entre voirie et réseaux d’eau et d’assainissement
Authors: Denis Jérôme , Florentin Daniel
Published: June 2022

Dans un grand nombre de collectivités, la gestion des réseaux techniques d’eau et d’énergie est insérée dans une direction chargée de la voirie. Cette organisation traduit une interdépendance entre le souterrain et la surface qui nourrit des formes de coordination asymétrique, la voirie « dictant » généralement les occasions de travaux, indépendamment des besoins spécifiques des réseaux. Cette hiérarchie des services témoigne de la « sensibilité politique » de la voirie, surface urbaine dont chacun fait l’expérience quotidiennement. S’appuyant sur une enquête qualitative de 18 mois en France métropolitaine, cet article montre que depuis quelques années, cette hégémonie de la voirie est remise en cause par la mise en place progressive de politiques de gestion patrimoniale spécifique aux réseaux, à laquelle s’ajoutent une écologisation de certaines pratiques d’aménagement, et une contrainte budgétaire accrue sur les finances locales. Ce triple processus contribue à une forme de « tournant patrimonial » qui reconfigure les interdépendances au sein de services techniques, et se traduit dans les services par de nouvelles manières de « faire compter » les réseaux techniques d’eau et d’assainissement et leur entretien face à la voirie.
Qualité de la gouvernance et son impact sur l’économie informelle en Tunisie
Authors: Toumi Sofiane
Published: June 2022

L’objectif de cet article est d’identifier la relation entre la qualité de la gouvernance et l’économie informelle, il s’agit de mettre en évidence la contribution des bonnes pratiques de gouvernance à l’atténuation de l’ampleur des activités informelles. Pour cela, nous évaluons d’abord la qualité de la gouvernance en Tunisie en appréciant son état aussi bien au niveau global que local, ensuite nous établissons un état des lieux de la sphère informelle en Tunisie, ses caractéristiques et ses déterminants, puis, nous dégageons le rôle des bonnes pratiques de gouvernance dans la limitation des conséquences néfastes de l’économie informelle. Enfin, à la lumière des analyses faites tout au long de l’article, nous apportons des recommandations permettant de renforcer la qualité de la gouvernance et nous proposons des actions concrètes aidant à relever les défis futurs en matière d’atténuation de l’informalité et de lutte contre la corruption qui ronge l’économie tunisienne.
L’internationalisation des entreprises marocaines en Afrique Subsaharienne : Quels enjeux ?
Authors: Dafir Amine
Published: June 2022

Le Maroc s’est engagé, depuis plusieurs années, à consolider son positionnement sur les marchés africains pour des raisons stratégique, géopolitique et économique. En diversifiant ses actions d’influence, combinant des outils économiques, culturels et religieux, le Maroc vise l’amélioration de sa présence dans les chaînes de valeur du continent et le renforcement de son intégration régionale. Une stratégie qui lui a permis de devenir un investisseur majeur dans l’Afrique Subsaharienne et surtout dans les pays de l’Afrique de l’Ouest. Par conséquent, le Maroc enregistre depuis plusieurs années une tendance croissante des investissements sortants vers les pays de l’Afrique Subsaharienne de telle sorte que ça devient une orientation stratégique des entreprises nationales souhaitant internationaliser leurs activités. D’ailleurs, les pays de l’Afrique Subsaharienne s’accaparent plus que la moitié des stocks d’IDE sortants plaçant le Maroc en tant que deuxième investisseur africain en Afrique Subsaharienne après l’Afrique du Sud. Le présent article cherche à mettre en lumière les enjeux de cette présence accrue des investisseurs marocains en Afrique Subsaharienne et les défis de l’internationalisation des entreprises nationales dans cette zone stratégique pour le pays.
Une évaluation des politiques européennes en direction de l’industrie au Maroc
Authors: Moisseron Jean-Yves , Guesmi Khaled
Published: June 2022

Le présent article à étudier la politique euro-méditerranéenne en faveur de l’industrie au Maroc en interrogeant les acteurs de terrain. Les principaux résultats sont les suivants : la politique européenne concernant l’industrie au Maroc, n’est pas directement centrée sur l’industrie mais plutôt sur l’accompagnement à la mise en place des accords de libre-échange et au développement du commerce. Ces politiques influencent cependant l’industrie en raison de l’impact des accords d’association. Cela est vrai tant dans l’accord de libre-échange, que dans la l’aide européenne, avec les politiques de mise à niveau ou les programmes d’assistance, le programme d’appui à la croissance et à la compétitivité. Le Maroc affiche par ailleurs, une volonté de développer son secteur industriel, notamment grâce à la mise en place de plans successifs. Ceux-ci ont permis de favoriser l’émergence de secteurs comme l’automobile. En ce qui concerne les défis, les besoins locaux et le bien-être des populations, les acteurs interrogés sont globalement d’accord avec les orientations de libéralisation du commerce international du Maroc. Certains souhaitent l’encadrer dans une politique industrielle locale, intervenant surtout dans la qualité de l’environnement économique tout en suscitant l’émergence de groupes industriels nationaux. Les craintes concernent surtout la mise en place de l’ALECA qui risquerait d’accentuer la pression concurrentielle sur l’industrie marocaine. Même si la question du genre est pertinente pour l’analyse de l’industrie, elle n’apparaît pas comme un sujet de préoccupation pour les acteurs.
En plein ciel de gloire. Vie de Guynemer en CII tableaux , dernier volet de Bleu Horizon
Authors: Lemonnier-Delpy Marie-Françoise
Published: June 2022

L’épais volume disparate de Bleu Horizon se clôt sur un scénario de commande rédigé par Roland Dorgelès. « Cette œuvre » dans laquelle Roland Dorgelès, en avant-propos du texte, dit s’être « astreint […] à respecter la vérité » offre un traitement épique de l’engagement de l’aviateur. On interrogera la place de ce scénario dans Bleu Horizon ainsi que les choix scénaristiques opérés par R. Dorgelès.
L’évocation de l’occupation Allemande dans Le Réveil des morts de Roland Dorgelès
Authors: Nivet Philippe
Published: June 2022

Le Réveil des morts de Roland Dorgelès, paru en 1923, est un grand roman sur l’histoire de la « première reconstruction » dans l’Aisne, celle qui a suivi la Première Guerre mondiale. Mais il se réfère également, quoique de manière beaucoup plus succincte, à l’occupation qu’a subie ce département entre 1914 et 1918. Cet article met en valeur les différentes évocations de cette occupation dans le roman : l’existence d’une Kommandantur , la germanisation des odonymes, les déplacements de population au sein des territoires occupés, les relations entre les occupants et les occupés et en particulier la question des enfants de « Boches », ainsi que la politique de terre brûlée pratiquée par les Allemands lors de leur retraite de 1917. Très bien documenté sur les modalités de la reconstruction, Roland Dorgelès semble l’être également sur l’occupation qu’a subie le département, évoquant des thèmes qui avaient sensibilisé l’opinion publique, mais aussi des questions peu connues, comme le rappel de l’allocation versée aux réfugiés pour les évacués.
Le Mystère du Louvre-Lens de Dominique Catteau ou le roman policier mis à mal ?
Authors: Platel Frédéric
Published: June 2022

Stupeur et tremblements : entre Béthune et Douai, dans la ville élue Sous-préfecture du Pas-de-Calais, c’est la consternation, l’émoi : Whodunit , contraction de « whose [has] done it ? », communément traduit par « qui l’a fait ? ». L’expression, substantivée, qui catégorise le roman policier invitant par une série d’indices donnés à identifier un coupable dans une affaire à caractère criminel vaudrait pour le roman de Dominique Catteau, Le Mystère du Louvre-Lens . Du directeur du célèbre musée au commissaire du secteur, tout le monde, jusqu’au criminologue parisien dépêché sur place… et au lecteur lui-même, voudrait débrouiller cette affaire, apporter des réponses aux questions qui se posent, détenir la clé de l’énigme… Mais à regarder de près l’intrigue bâtie par Dominique Catteau, on comprend que déjà ce sont d’autres questions qui se font jour : qui les enquêteurs diligentés pour cette affaire sont-ils vraiment ? Le « qu’a-t-il donc fait ? » ne primerait-il pas le « qui l’a fait ? ». Qu’a fait cet individu dont les agissements tombent sous le coup de la loi ? Et que fait du policier un auteur qui semble afficher de prudentes réserves sur l’intérêt supposé de ce genre, et sur sa pertinence, dans un roman qui paraît bien s’en réclamer ? Conçu sur le mode de l’échappée, Le Mystère du Louvre-Lens nous ramène à nous-mêmes et ne cesse d’interroger… le devenir de l’homme en société, l’état de la société des hommes, le monde comme il va.
Dynamics of $ L^p $ multipliers on harmonic manifolds
Authors: Biswas Kingshook , Sarkar Rudra P.
Published: June 2022

Let $ X $ be a complete, simply connected harmonic manifold of purely exponential volume growth. This class contains all non-flat harmonic manifolds of nonpositive curvature, and in particular all known examples of non-compact harmonic manifolds except for the flat spaces. We use the Fourier transform from [1] to investigate the dynamics on $ L^p(X) $ for $ p > 2 $ of certain bounded linear operators $ T : L^p(X) \to L^p(X) $ which we call "$ L^p $-multipliers" in accordance with standard terminology. Examples of $ L^p $-multipliers are given by the operator of convolution with an $ L^1 $ radial function, or more generally convolution with a finite radial measure. In particular elements of the heat semigroup $ e^{t\Delta} $ act as multipliers. Given $ 2 < p < \infty $, we show that for any $ L^p $-multiplier $ T $ which is not a scalar multiple of the identity, there is an open set of values of $ \nu \in {\mathbb C} $ for which the operator $ \frac{1}{\nu} T $ is chaotic on $ L^p(X) $ in the sense of Devaney, i.e., topologically transitive and with periodic points dense. Moreover such operators are topologically mixing. We also show that there is a constant $ c_p > 0 $ such that for any $ c \in {\mathbb C} $ with $ \operatorname{Re} c > c_p $, the action of the shifted heat semigroup $ e^{ct} e^{t\Delta} $ on $ L^p(X) $ is chaotic. These results generalize the corresponding results for rank one symmetric spaces of noncompact type and harmonic $ NA $ groups (or Damek-Ricci spaces).
The Cauchy problem for coupled system of the generalized Camassa-Holm equations
Authors: Ming Sen , Du Jiayi , Ma Yaxian
Published: June 2022

Local well-posedness for the Cauchy problem of coupled system of generalized Camassa-Holm equations in the Besov spaces is established by employing the Littlewood-Paley theory and a priori estimate of solution to transport equation. Furthermore, the blow-up criterion of solutions to the problem is illustrated. Our main new contribution is that the effects of dissipative coefficient $ \lambda $ and exponent $ b $ in the nonlinear terms to the solutions are analyzed. To the best of our knowledge, the results in Theorems 1.1 and 1.2 are new.
Think Globally, Act Regionally to Optimize Quality Health System Management
Authors: Moopen Alisha , Boucher David , Mandhani Rahul , Arshanapalai Malathi
Published: June 2022

Initiatives to address the quality in health system management have become a global phenomenon. The complexity of providing quality healthcare is arguably unmatched. From the wealthiest of regions to those in the direst conditions, the efficacy of integrating quality management principles and practices is being accepted by executives, practitioners, and governmental authorities alike. This global level of agreement is based on a wealth of knowledge and experience gained over many decades across a multitude of industries. The challenge is instituting the transformative capability of quality management processes into workable systems that will optimize care across healthcare services globally. This paper is based on the perspective that orienting systems to the delivery and ongoing improvement of quality is fundamental to progress. The authors argue that healthcare leaders can affect lasting change by adopting universally proven precepts of quality enterprise wide and executing them across channels to meet expectations across the spectrum of patient and healthcare worker populations.
Call to Action
Authors: McCaskill Angela
Published: June 2022

Low quality healthcare services can hinder economic and social development, result in premature death and disability, and waste human capital. To compound pre-pandemic healthcare access and equity issues, the quality of care that is delivered in low, lower-middle, as well as in high-income OECD countries can be uneven, poorly funded, and without adherence to standardization. COVID-19 has highlighted the importance of high-quality healthcare, while exacerbating many challenges. How services are delivered and the underlying guidance or standards that support the delivery of high-quality care are not necessarily a part of the regular healthcare reform dialog. This position paper introduces a new standard, ISO CD 7101, that seeks to address problems and offer solutions for the quality of healthcare delivered globally. This paper describes the need for such a standard, its history, advantages, and how it answers the global call to action set forth by the OECD, the World Bank, and the World Health Organization.
Effects of Substitution of Fine Aggregate with Recycled Asphalt Pavement on Compressive Strength of Normal Concrete
Authors: Sanchaiwut Masiya , Thumrongvut Jaksada , Pantawee Saksith , Seangatith Sittichai
Published: June 2022

In this research, the compressive strength of concrete utilizing fine recycled asphalt pavement (fine RAP) as fine aggregate substitution for natural sand is investigated at weight percentages of 10, 20, 30, 40, 50, 60, 70, 80, 90 and 100 percent. The compressive strengths of concrete were designed according to ACI 211.1 standard for 18 MPa, 25 MPa, 32 MPa and 40 MPa at 28 days of curing. The compressive strengths of the concrete using fine RAP aggregate in this study were compared to the ones that use the natural aggregate in the same proportions. From the results of the tests, it was found that the compressive strength of concrete using fine RAP is dependent on the amount of Fine RAP used in the mix proportions. Test results also indicated that there is a systematic reduction in the compressive strengths with the increase in the weight percentages of the fine RAP. The relationship between the normalized compressive strength and the weight percentages of the fine RAP were proposed. Finally, a suggested strength reduction factor for the concrete using fine RAP as aggregate was also proposed.
Numerical Simulation of Forging Process of Ultra-High Strength Stainless Steel
Authors: Ma Jian , Gao Qi , Yang Peng , Wang Bao Shan , Zhang Hong Liang , Feng Guang Hong
Published: June 2022

In this work, the forging process of ultra-high strength stainless steel has been simulated based on Simufact Forming. The simulation results show the temperature drop at the ends of the workpiece is obvious, and the strain is difficult to penetrate. Affected by the shape of the workpiece, the strain is mainly located on the surface during the first and second passes of stretching and chamfering, while the strain penetrates toward the center in the middle passes of stretching. It is noted that the degree of dynamic recrystallization (DRX) of center microstructure is insufficient due to the strain is slightly larger than the critical strain of DRX. Affected by temperature field and strain field, dynamic recovery is the main softening mechanism during radial forging.
Dewatering Treatment and Catalytic Application of Sludge by Glow Discharge Plasma
Authors: Li Ting , Huang Shao Yong , Gan Jia Ming , Shao Min Li , Wang Lei
Published: June 2022

In this paper, glow discharge plasma (GDP) was used to remove organic contaminants of sludge and improve sludge dewaterability. Fe-rich sludge as a catalyst combined GDP to form heterogeneous Fenton reaction, which was used to remove 2,4-dichlorophenoxyacetic acid (2,4-D) in aqueous solution. The surface micrographs and chemical composition of Fe-rich sludge was analysed by the Scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS). The effect of initial pH0 on hydrogen peroxide (H2O2) yield in GDP was discussed. The removal of 2,4-D was associated with the synergetic effect of adsorption and oxidative, and hydroxyl radicals (•OH) play a dominant role. This study provides an environmentally-friendly technology to improve sludge dewaterability and a potentially low-cost catalyst for 2,4-D removal in water, which is significant for the reuse of Fe-rich sludge.
Universal Multi-Parametric Model to Design Devices Based on Magneto-Rheological Fluids
Authors: Brunetti Giovanna , Semeraro C. , Olabi Abdul Ghani , Caggiano Mariateresa , Dassisti Michele
Published: June 2022

This paper presents an innovative Universal Multi-Parametric Model for designing devices using Magneto Rheological Fluids based on the explication of relationships between the functional requirements and the corresponding combination of related properties (chemical and physical)A rationale thus results to select the best MRF for a specific application. This might constitute a useful tool providing organized knowledge on the MRF world for scholars and practitioners approaching to the world of MRF technology as well as a support to engineers/designers during the early design tasks.
Optimization of the Metal Nozzle for High-Temperature Extrusion Additive Manufacturing
Authors: Xu Chen Yu , Long Xi Rui , He Yi Wei , Fang Xia , Huang Kun Lan , Huang Ji Gang
Published: June 2022

Material extrusion additive manufacturing (ME-AM) builds 3D models by extruding materials through a nozzle layer by layer. As the development of materials, an increasing demand of the high-temperature extrusion has emerged in additive manufacturing (AM). While the smooth and stable extrusion process at high temperature relies heavily on the nozzle, the optimization study on the metal nozzle is reported in this work. From current brass and steel nozzles, two optimized nozzles (a steel nozzle with brass embedded and a steel nozzle with brass encircled) have been designed and the thermal conductivity has been studied by simulation analysis. Then the thermal deformation of designed nozzles and traditional nozzles have been investigated at the temperature of 410°C. Conducting the extrusion and printing tests, the extrusion performance of the proposed nozzles has been compared to that of traditional nozzles. The results indicate that the proposed nozzles lead to the better thermal distribution as well as the stronger resistance to thermal deformation compared to the traditional brass nozzle. The designed steel nozzle with brass encircled shows the excellent extrusion performance and printing performance.
Changing Spectrum of Acute Encephalitis Syndrome in India and a Syndromic Approach
Authors: Misra Usha K. , Kalita Jayantee
Published: June 2022

Acute encephalitis syndrome (AES) refers to an acute onset of fever and clinical neurological manifestation that includes mental confusion, disorientation, delirium, or coma, which may occur because of infectious or non-infectious causes. Cerebrospinal fluid (CSF) pleocytosis generally favors infectious etiology, and a normal CSF favors an encephalopathy or non-infectious AES. Among the infectious AES, viral, bacterial, rickettsial, fungal, and parasitic causes are the commonest. Geographical and seasonal clustering and other epidemiological characteristics are important in clinical decision making. Clinical markers like eschar, skin rash, myalgia, hepatosplenomegaly, thrombocytopenia, liver and kidney dysfunction, elevated serum CK, fronto-temporal or thalamic involvement on MRI, and anterior horn cell involvement are invaluable clues for the etiological diagnosis. Categorizing the AES cases into neurologic [Herpes simplex encephalitis (HSE), Japanese encephalitis (JE), and West Nile encephalitis (WNE)] and systemic (scrub typhus, malaria, dengue, and Chikungunya) helps in rational utilization of diagnostic and management resources. In neurological AES, cranial CT/MRI revealing frontotemporal lesion is consistent with HSE, and thalamic and basal ganglia lesions are consistent with JE. Cerebrospinal fluid nucleic acid detection test or IgM antibody for JE and HSE are confirmatory. Presence of frontotemporal involvement on MRI indicates acyclovir treatment pending virological confirmation. In systemic AES, CT/MRI, PCR for HSE and JE, and acyclovir therapy may not be useful, rather treatable etiologies such as malaria, scrub typhus, and leptospirosis should be looked for. If smear or antigen for malaria is positive, should receive antimalarial, if negative doxycycline and ceftriaxone should be started pending serological confirmation of scrub typhus, leptospira, or dengue. A syndromic approach of AES based on the prevalent infection in a geographical region may be developed, which may be cost-effective.
COVID-19 and Dementia; Hard to Forget Yet Haunting Forgetfulness!
Authors: Kaliappan Ariyanachi , Gaur Archana , Sakthivadivel Varatharajan , Balan Yuvaraj , Tadi Lakshmi Jyothi Tadi , Sundaramurthy Raja
Published: June 2022

The current pandemic has affected almost everyone worldwide. Although the majority of people survive the illness, bad cognitive repercussions might last a long time, resulting in a lower quality of life and disability, particularly in severe cases. We tried to understand and bring together the various possible mechanisms leading to dementia in COVID-19. The link between COVID-19 and dementia will help public health workers plan and allocate resources to provide better care for a community suffering from sickness and improve quality of life. A conceptual framework for care of infected people in the older age group and care of dementia people is proposed.
Movement Disorder in Demyelinating Disease
Authors: Singh Rashmi , Pandey Sanjay
Published: June 2022

Movement disorders may be one of the neurological manifestations of demyelinating disorders. They can manifest in Parkinsonism or a wide spectrum of hyperkinetic movement disorders including tremor, paroxysmal dyskinesia, dystonia, chorea, and ballism. Some of these disorders occur during an acute episode of demyelination, whereas others can develop later or even may precede the onset of the demyelinating disorders. The pathophysiology of movement disorders in demyelination is complex and the current evidence indicates a wide involvement of different brain networks and spinal cord. Treatment is mainly symptomatic and oral pharmacological agents are the mainstay of the management. Botulinum toxin and neurosurgical interventions may be required in selected patients.
Psychiatry training for medical students: A global perspective and implications for India’s competency-based medical education curriculum
Authors: Gupta Snehil , Menon Vikas
Published: June 2022

Competency-based medical education curriculum (CBME) has received traction worldwide. However, its adoption and implementation have significantly varied across the globe. The National Medical Commission, India (2019) has adopted CBME to improve the quality and content of training of medical students. However, the ongoing COVID-19 pandemic has spawned several challenges implementing the CBME. Therefore, there is a need to reflect on using novel teaching and assessment methods to enrich medical and psychiatric training. In this paper, we aimed to study global trends and characteristics of competency-based psychiatry training programs and how these experiences can be utilized to overcome challenges and facilitate the implementation of CBME in Psychiatry in the Indian context. A literature search was conducted using PubMed and Google Scholar databases. The findings are presented narratively. Psychiatry training for medical students greatly vary across the globe. High-income countries mainly have implemented CBME and have incorporated psychiatry training during the foundation/pre-clerkship period itself. There is more reliance on skill development and flexible and learning-based training vs. time-based training. Various enrichment activities have been incorporated into the medical curriculum to promote and strengthen psychiatry training for medical students, particularly in developed nations, which have yielded positive results. Although the COVID-19 pandemic has adversely affected the medical student’s training, it has reiterated the significance of skill-based education and opened novel avenues for implementing the CBME.Medical educationists need to adapt themselves to provide CBME to the students. Making structural, curricular changes, orienting teachers, and students about the CBME, mentoring teachers, adopting novel training and assessment methods, utilizing enrichment activities, collaborating with educational institutions and technology providers, periodically evaluating the implementation of the CBME, and making appropriate course corrections are essential. In addition, there is a need to address structural barriers, such as lack of workforce, for better realization of the CBME objectives.eriodically evaluating the implementation of the CBME, and making appropriate course corrections are essential. Additionally, there is a need to address structural barriers, such as lack of workforce, for better realization of the CBME objectives.
Development and validation of a peer support programme for the prisoners with mental and substance use disorders in India
Authors: Thekkumkara Sreekanth Nair , Jagannathan Aarti , Muliyala Krishna Prasad , Murthy Pratima
Published: June 2022

Background

The prevalence of mental health problems and substance use disorders is high in prisons. There is a need to develop effective and sustainable models in prison to address their mental health demands.

Aim

The study aimed to develop and validate a peer support programme (PSP) for prisoners with common mental and substance use disorders (SUD).

Method

The PSP was developed by reviewing the literature and expert interviews and validated by seven experts.

Result

The expert interview brought out a total of 10 themes. The final components included in the content of the peer support interventions were information about mental health issues, identification of the cases, basic counseling skills, psycho-education, early warning signs and symptoms, managing substance use by motivational interviewing, and suicidal gatekeeping.

Conclusion

This study describes the development of a comprehensive PSP, and it needs to be tested to examine its feasibility and effectiveness in addressing mental health problems in prison settings.
The Correlation between Lumbosacral Transitional Anatomy and Pars Defect
Authors: Gonzales-Portillo Gabriel S. , Avila Mauricio J. , Rizvi Omar , Dumont Travis M.
Published: June 2022

Background:

Transitional anatomy and pars defects are two common incidental findings seen on imaging of the lumbosacral spine. The purpose of this study was to investigate whether there is a correlation between these two lumbar spine phenomena.

Materials and Methods:

A retrospective review of spinal imaging was conducted of patients presenting with thoracolumbar fractures at our Level I Trauma Center between 2017 and 2018. Computed tomography scans from 260 patients were obtained and assessed for the presence of lumbosacral transitional anatomy and pars defect.

Results:

From the 260 patients reviewed, 16 patients had transitional anatomy (6%) and 20 patients had lumbar non-traumatic pars defect (8%). Only one patient presented with both transitional anatomy and pars defect. Overall, there was no difference in incidence of pars defect whether transitional lumbosacral anatomy was present (5%) or not (6.25%), P = 1.00, Fisher’s exact test.

Conclusion:

The findings suggest that patients with transitional anatomy do not have an increased association with lumbar pars defects.
Retrograde nasal intubation for an anticipated difficult intubation
Authors: Linnet Sharon , Hemanth Natham , Samantaray Aloka , Rao M. Hanumanth
Published: June 2022

A 58-year-old female patient with recurrence of carcinoma in the angle of the mouth on the left side was posted for composite resection and Pectoralis major myocutaneous flap reconstruction. The patient had carcinoma left buccal mucosa 1 year back and had undergone left partial mandiblectomy and radiotherapy. On airway examination (MPG) could not be assessed; on mouth opening one-and-half finger was admitted. There was a 4 cm × 4 cm ulceroproliferative growth in the left angle of the mouth extending to lower lip, which was bleeding on touch. After shifting to the operating theatre, venous access was secured with a with a wide-bore cannula. Standard monitoring was connected and preoxygenation was done. Under strict aseptic precaution under local anaesthesia, trachea located with Touhy's needle. Epidural catheter passed through the needle into the larynx and taken out through the oral cavity and Ryle's tube, which the patient already had for feeds, was pulled and taken out of the oral cavity. Catheter tip was tied to it and pulled out through the nostril and passed through murphy's eye of 6.5 mm (ID ETT) and lower end pulled, thereby pulling ETT into the trachea, cuff was inflated and tube fixed at 25 cm. General anaesthesia was administered. Thorough airway assessment, preparat ion and counselling of patient help in reducing airway-related morbidity and mortality.
Ensuring safe blood supply
Authors: Bhasker P. M. Bala , Williams Susan
Published: June 2022

Background:

The use of unscreened blood exposes the patient to many transfusion-transmitted infections (TTIs) including hepatitis B and C viruses, human immunodeficiency virus (HIV), malaria and syphilis, among others. Thus, blood transfusion demands for meticulous pre-transfusion testing and screening.

Methods:

In this retrospective study carried out from September 2019 to September 2021, 5 mandatory screening tests for TTIs, namely, anti-HIV 1 and 2, anti-hepatitis C virus antibodies, hepatitis surface antigen (HBsAg), serological testing for syphilis and malarial parasite antigen detection were performed.

Results:

From 2019 September to 2021 September, 2576 blood donations (n = 2474; 96% males) were studied. Of these, 529 (20.5%) were from voluntary donors (VD) and 2047 (79.5%) from replacement donors (RD). Thirty-four (1.3%) of the total 2576 blood donors tested positive for one of the TTIs, including 6 (17.6%) VD and 28 (82.4%) RD.

Conclusions:

Strict selection of blood donors is mandatory and the need to increase voluntary blood donations can ensure safe blood supply and reducing the occurrence of TTI.