bluuebunny/crossref_metadata_2025 huggingface dataset:
PERBANDINGAN PERTUMBUHAN TANAMAN PORANG (Amorphophallus muelleri) AGROFORESTRY DAN MONOKULTUR PADA KELOMPOK TANI SARI BUNGA KAYU KABUPATEN LUWU TIMUR
Authors: Maria Maria , Ayu Srida Mitra , Lani Lani
Published: February 2022

This study aims to determine the comparison of the growth of porang plants managed by agroforestry and monoculture. This research took place from April to May 2021. The data was collected in the form of primary data and secondary data. This study was a completely randomized design consisting of 2 treatments and eight replications on agroforestry and monoculture land so that there were 32 experimental units. Treatment using media M1=Soil (100%) and M2=Soil + husk charcoal. Furthermore, analysis of variance (Manova) was carried out; the analysis of variance showed that on agroforestry land, the treatment had a very significant effect on stem height and substantially impacted the number of leaves. In contrast, in monoculture, the treatment significantly impacted stem height and had no significant effect on the number of leaves. Based on the results of the research, the best porang plant growth was found on agroforestry land that used soil + husk charcoal in terms of plant height parameters and a number of leaves with an average plant height value of 27.2 cm and gave the best results on the number of leaves with an average value of 3 strands. At the same time, the lowest porang plant growth was on monoculture land with an average plant height value of 19 cm and the number of leaves with an average value of 1 strand.
Running activity, preparation and participation in marathon runs by amateurs between the age of 42-51 – a case study
Authors: Chryczyk Katarzyna , Mirek Waclaw , Mirek Katarzyna , Ozimek Mariusz , Čepička Ladislav
Published: February 2022

Aim. In the research, we looked for the relationship between the level of training activity and aerobic capacity as well as the result in the marathon run by an amateur aged 42-51. Materials and Methods. A progressive test was used to determine the threshold speed and load of the training activity. A 10- year period was analysed among amateur runners between the age of 42 and 51. The annual and DSP (Direct Start Preparation) training activity loads were determined. The strength of the relationship between the applied load of training activity and the result in the marathon was assessed, as well as the effectiveness of forecasting the result in the marathon. Results. An average annual volume over 2,500 km (194 hours) was found. During the DSP period, there was definitely an increase in workload. On average, in the DSP, the sub-threshold, threshold and supra-threshold measures constituted 65.7%- 19.4%-14.9%, respectively. A strong correlation was found between the result in the marathon and the annual volume, as well as the supra-threshold measures. Conclusions. The examined person presented a high level of activity, which allowed to maintain a high and stable level in the marathon and a high level of efficiency expressed by the VO2max indicator. The high assessment of the progressive test in estimating the result in the marathon was confirmed.
Distanční výuka - krok vpřed nebo krok vzad?
Authors: Hořká Zuzana
Published: February 2022

Přechod na distanční výuku znovu otevřel otázku metodiky výuky cizích jazyků. Zimní semestr 2020/21 proběhl celý on-line, což se stalo výzvou zejména pro studenty prvních ročníků, kteří museli zvládnout přechod na zcela jinou formu studia, aniž by se mohli osobně seznámit s vysokoškolským prostředím. Vedení Matematicko-fyzikální fakulty se vzhledem k situaci na jaře 2020 rozhodlo přijmout všechny zájemce o studium bez přijímacích zkoušek, což do prvního ročníku přivedlo české i zahraniční studenty se značnými rozdíly ve znalosti angličtiny. Situace byla nová i pro vyučující, kteří přišli o možnost na tradičním úvodním soustředění předat studentům informace a doporučit jim úroveň kurzu angličtiny podle jejich znalostí.Článek shrnuje zkušenosti z prvního semestru vyučovaného pouze distanční formou. Rozborem anonymního dotazníku studentů kurzů prvního ročníku Anglický jazyk pro mírně pokročilé (přibližně A2/B1 podle CEFR) a Anglický jazyk pro středně pokročilé (přibližně B2/C1 podle CEFR) se snaží vyhodnotit používané aktivity a navrhnout zlepšení pro případnou on-line výuku v dalších semestrech.
Socialisation of Adolescents with Cognitive Disorders through Emotional Intelligence
Authors: Vovchenko Olha A. , Lytvynova Nataliia A. , Tsekhmister Yaroslav V. , Hoshovska Dariia T. , Vichalkovska Natalia K.
Published: February 2022

Objective: To study the influence of the development of emotional intelligence of adolescents with CDs through the involvement of their parents and teachers in socialisation. The emotional sphere of adolescents with cognitive disorders (CDs) is no less important than correcting their cognitive development. The methods that allow fixing the patients' ability to recognise emotions don't realise the functioning of their emotional sphere.

Method: Questionnaires were used for diagnosing the emotional interaction of parents and teachers with adolescents with CD, the questionnaire for measuring the socialisation of adolescents "How adapted I am to life" by A. Furman, statistical analysis ANOVA, correlation analysis r of Pearson, content analysis of the qualitative data.

Results: Standardised questionaries developed that reflect the formation of emotional intelligence of the adolescent with CDs through the interaction with their parents and teachers. Empirical data obtained while research resulted in statistically significant correlations of emotional intelligence between parents, teachers and psychologists and social adaptation measured via Furman questionary. It was found that the positive emotional interaction and tactile support of adolescents with CDs with their parents increases the level of social adaptation. Similar correlations were found in teachers' emotional interaction with the adolescents with CDs. The number of parents who showed a low emotional and tactile interaction with adolescents was 20%.

Conclusions: Detected statistically significant correlations proved that the high role of the participation of parents and teachers in the process of forming emotional intelligence contributes to the successful socialisation of adolescents with cognitive disorders.
http://www.bioinformation.net/018/97320630018050.htm
Authors:   Department of Medical Biochemistry, Dr. A.L.M PG Institute of Basic Medical Sciences, University of Madras, Chennai, Tamil Nadu, India, Daniel Priscilla
Published: February 2022

Insulin resistance is linked to impaired cell metabolism and survival in the peripheral tissues, as well as increased oxidative stress and activated inflammatory responses. Chronic High fat diet insulin resistant to exposure results in liver damage, impaired glucose homeostasis, hyperinsulinemia, late pancreatic-cell failure to generate insulin due to cell exhaustion, and subsequent hyperglycaemia, all of which are hallmarks of Type 2 Diabetes Mellitus (T2DM). Therefore, it is of intrest to document a short review on the impact of a high-fat diet with insulin resistance.
Transforming subjectivity When aiming for mutually transformative processes in research with children
Authors: Marschall Anja
Published: February 2022

The aim of this paper is to investigate how children use their participation in research as apotential transformative social practice in everyday life. The concept of transformative socialpractice will be discussed in relation to the notion of transformation.Through empirical examples provided by Holly (12) and Oliver (11), the article argues thatresearch processes open up possibilities for understanding ourselves (researchers andparticipants) in new ways.‘Life Mapping’ - as dialogical method in research with children - will be presented and reflectedupon as a way for children to develop different understandings of themselves, their families, andeveryday life. This emphasizes the connection between the use of child-relevant methodologies andhow specific children can bring dialogues from the research process in to play in their everydaylives.Data is drawn from a qualitative study and is a part of a PhD project studying children’s everydaylives with two households as a result of parental divorce. The project involves ten children aged 8-12 and their parents.
The trajectory of food as a symbolic resource for international migrants
Authors: Morasso Sara Greco , Zittoun Tania
Published: February 2022

This paper explores the trajectories of food and how culinary practices evolve over time in relation to a migrant’s experience. Our focus is on international mothers adjusting to life in London. We identify a connection between eating practices and evolving identities. In line with a stream of research in cultural psychology, we consider food as a symbolic resource mobilized by migrants to provide some material support to their processes of adaptation to a new country. In this respect, we introduce the notion of malleable symbolic resource in order to highlight the ductility of food in relation to an individual’s evolving personal culture. On this basis, we propose to describe ductile trajectories of food in relation to three important steps: where food and eating practices come from; with whom food is consumed and for what goal it is chosen.
New Tools in Social Practice: Learning, Medical Education and 3D Environments
Authors: Ludvigsen Sten , Fjuk Annita
Published: February 2022

Learning with different kinds of ICT-based tools is an important issue in today's society. In this article we focus on how design of technology rich environments based on state of the art learning principles can give us new insights about how learning occur, and how we can develop new types of learning environments. Medical education constitutes the subject domain. There has been a considerable effort to develop 3D technologies in this field, and the article provides a careful review of how these technologies are applied. There is, however, a substantial gap between these advances and the use of technologies in medical education. Related work proposes individualistic assumptions or metaphors that do not focus explicitly on learning and technology mediation. Based on theoretical analysis of previous literature in the field we argue that there is a need for a new unit of analysis that includes the relationship between individual and collective activity and the role of technology herein. The socio-cultural and especially activity theory is taken as the perspective which gives the possibility to develop the argumentation about the unit of analysis. The unit of analysis also has implications for design of 3D environments. The design principles are elaborated upon and examples are given in relation to an application called Matador (Medical Advanced Training in an Artificial Distributed Environment). Matador is aimed at developing a simulation environment for training in emergency medicine.
Caring Power – Coercion as Care
Authors: Svensson Kerstin
Published: February 2022

The article analyses the compulsory care of drug misusers in Sweden. An historical analysis of this field of work as a part of the Swedish welfare state highlights historically changing legislations, institutions, understandings and practices. Following Foucault, it is argued that it is impossible to distinguish between power and care and that confusion about coercive care is a result of not acknowledging power. Empirical studies of current social work point to the significance of different institutional settings. The author's study of the Swedish probation service shows that social workers and clients may adopt different positions in relation to each other and that their experiences of the practice of social work depend on the congruence or disparity between these positions. The problematic role of motivation in coercive care is highlighted. While some scholars claim that motivation is not possible in coercive institutions, the author relates motivation to the caring power arguing that social work is always aimed at normality and that care is exercised to achieve normality. The promise of an improved life situation may make people in need of help adapt to the demands of the helper, and the caring power can be seen as a way to provide help for individuals who do not realize that they are in need of care.
Epidemiological, Clinical, Etiological and Therapeutic Study of Drug eruption in HIV-infected patients in the two Accompaniment Care Unit and Advice of Bamako, Mali
Authors: Karabinta Yamoussa , Niangaly Dienebou , Traore Chata , Konate Issa , Karambe Tenin , Tall Koureissi , Guindo Binta , Gassama Mamadou , Diakite Mamoudou , Dicko Adama Anguissa , Seudjip Nono Lydie Joelle , Faye Ousmane
Published: February 2022

Background: The increase in prescriptions of antiretrovirals (ARVs) implies the increasing occurrence of side effects, including skin manifestations. The objective of this work was to identify the epidemiological and therapeutic aspects of drug eruptions during ARV treatment in the support and counseling units (SCU) of commune IV of the district of Bamako. Material and methods: In a documentary study, the data of patients living with HIV (PLHIV) followed in the SCUs between January 2008 and December 2010, i.e. 3 years, in strict respect of their confidentiality were collected. Parameters of interest included epidemiological, clinical and therapeutic characteristics. Results: The frequency of drug eruptions was 2.85% of cases, ie 50 patients out of 1748 PLWHA. Women accounted for 76% of cases with a sex ratio of 0.32. The mean age was 30.8 ± 11.46 years with extremes ranging from 5 to 60 years. PLHIV were in WHO clinical stage III, or 48% of cases. The mean time to onset of drug eruption was 23.5 ± 17.7 days. Common clinical manifestations were pruritus (24%), rash (22%) and Lyell’s syndrome (12%). 96% of patients (48 cases) were on ARVs, of which 78% were on nevirapine and 14% on efavirenz. The treatment was symptomatic. Conclusion: Antiretrovirals are sources of drug eruption despite their benefits in the treatment of HIV/AIDS. Rigorous monitoring is essential to prevent these harmful effects.
Hidden Consequences: Examining the Impact of NIL on Athlete Well-Being
Authors: Harris Hailey A. , Brison Natasha T. , Dixon Marlene A.
Published: February 2022

With the NCAA's NIL policy changes, many athletes will likely need to solve the issue of brand management, with many of them assuming the role themselves. Taking on this role will likely lead to even more investment in their athlete identity (i.e., role engulfment), which has negative consequences for the athlete (Hatteberg, 2020). Guided by the literature on role engulfment, this article investigates the hidden effects NIL may have on collegiate athletes and their well-being, along with various branding and legal implications.
Language Ideologies and Policies at Work: Obstructing Arabic Instruction from the French Colonial Era to the Present
Authors: Chakrani Brahim
Published: February 2022

This article analyzes France’s language policies regarding Arabic instruction, considering the historical relationship with the Arabic language and its speakers, from colonial to postmodern eras. The polemic surrounding Arabic instruction in the schools of the republic is not a nascent political development regarding minority linguistic rights, but, rather, a byproduct of ideologically motivated educational policies that aim to marginalize the role of Arabic, both within the Arab world and the French diaspora. The debate demonstrates the centrality of language ideologies in shaping France’s identities, both nationally and abroad, and the maintenance of French as well as Arabic, the language of France’s largest minority. France has historically promoted the dominance of the French language, including Francophonie’s inception (Kasuya 2001; Vigouroux 2013) in the post-independence era and laïcité in modern-day France (Tetreault 2021). Analyzing current political debates in France shows that the circulating ideologies that characterizes teaching Arabic is not born in a vacuum, but, rather, it continues a legacy of contention that has characterized France’s relationship with the Arabic speaking world.
A comparative study of bacterial diversity based on effects of three different shade shed types in the rhizosphere of Panax quiquefolium L.
Authors: Wang Xianchang , Guo Xu , Hou Lijuan , Zhang Jiaohong , Hu Jing , Zhang Feng , Mao Jilei , Wang Zhifen , Zhang Congjing , Han Jinlong , Zhu Yanwei , Liu Chao , Sun Jinyue , Shan Chenggang
Published: February 2022

Background

Shading is an important factor affecting the cultivation of American ginseng, as it influences crop quality and yield. Rhizosphere microorganisms are also crucial for normal plant growth and development. However, whether different shade types significantly change American ginseng rhizosphere microorganisms is unknown.

Methods

This study evaluated the rhizosphere soils of American ginseng under traditional, high flag and high arch shade sheds. High-throughput 16S rRNA gene sequencing determined the change of rhizosphere bacterial communities.

Results

The microbial diversity in rhizosphere soils of American ginseng significantly changed under different shading conditions. The bacteria diversity was more abundant in the high arch shade than flat and traditional shades. Different bacterial genera, including Bradyrhizobium, Rhizobium, Sphingomonas, Streptomyces and Nitrospira, showed significantly different abundances. Different shading conditions changed the microbial metabolic function in the American ginseng rhizosphere soils. The three types of shade sheds had specific enriched functional groups. The abundance of ATP-binding cassette (ABC) transporters consistently increased in the bacterial microbiota. These results help understand the influence of shading systems on the rhizosphere microecology of American ginseng, and contribute to the American ginseng cultivation.
Unraveling the hidden paleobiodiversity of the Middle Devonian (Emsian) crinoids (Crinoidea, Echinodermata) from Poland
Authors: Ausich William I. , Salamon Mariusz A. , Płachno Bartosz J. , Brachaniec Tomasz , Krawczyński Wojciech , Boczarowski Andrzej , Paszcza Karolina , Łukowiak Magdalena , Gorzelak Przemysław
Published: February 2022

Most previous publications on Devonian crinoids from the Holy Cross Mountains in Poland have concentrated on crinoid columns, and until now, little has been published about crinoid cups and calyxes. Herein, five crinoid taxa are described from an abundant occurrence of aboral cups and partial crowns from the Bukowa Góra Member (Emsian) in the Holy Cross Mountains of southern Poland. The following taxa are described:Bactrocrinitessp.,Codiacrinus sevastopuloisp. nov.,Halocrinites geminatus(Bohatý, 2005),Halocrinites schlotheimiiSteininger, 1831, and a single brachial plate from a flexible crinoid placed in Flexibiliaincertae sedis. Simple discoid holdfasts are also present encrusted to cylindrical stromatoporoids. These taxa are the first crinoids described from the remains of partial crowns from Emsian strata of Poland.
Clinicopathological Study of Spectrum of Muscle Disorders in a Tertiary Care Hospital
Authors: Sharma Mayank , Bijwe Sanjay R , Chavhan Snehal V , Rathod Arvind E
Published: February 2022

Introduction: The diagnostic approach to muscle disorders is often challenging due to paucity of literature, unavailability of ancillary facilities, affordability and improper sample collection. The role of pathologist in terms of categorising the muscle biopsy interpretation with limited resources plays an imminent role in guiding clinicians for further therapeutic approach. Aim: To analyse spectrum of various muscle disorders and to relate their clinical and histopathological findings. Materials and Methods: This was observational retrospective as well as prospective study of 63 muscle biopsies received during 10 years period from June 2009 to June 2019, at Department of Pathology in Grant Government Medical College, Mumbai, India. Slides of muscle biopsies received prior to June 2017 were restained and reviewed while muscle biopsies after this period were studied prospectively. Various histomorphological and histopathological (fascicular architecture, variation in size and shape of fibers, necrosis and degenerative/regenerative changes, nuclear characteristics, type and distribution of inflammatory cells along with interstitial changes) features were studied in detail and the findings were compared with similar previous studies. These findings when clubbed together with clinical, biochemical and Electromyography (EMG) findings, to guide the path towards appropriate diagnosis. Results: The present study evaluated and analysed 63 muscle biopsies, clinically, histopathologically and histomorphologically. Mean age was 30.6 years, 43 (68.25%) patients were males and 20 (31.75%) patients were females. A number of 12 (19.04%) patients were clinically diagnosed as having limb- girdle muscular dystrophy, followed by 9 (14.28%) patients as inflammatory myositis. Eight patients (12.69%) were diagnosed as Polymyositis (PM), five (7.93%) as Dermatomyositis (DM), one (1.58%) patient each of juvenile DM and inclusion body myositis. Histopathologically, the cases diagnosed were PM- 14 cases (22.22%) followed by muscular dystrophy (excluding limb-girdle muscular dystrophy)- 12 cases (19.04%) and limb- girdle muscular dystrophy- 9 cases (14.28%). conclusion: Although molecular and genetic studies are need of hour, histomorphological features helps in proper categorisation of cases, however close liaison between pathologist and clinicians is essential and histopathological findings should only be interpreted in light of clinical manifestations and laboratory findings.
Laparoscopic Pyeloplasty in Paediatric Age Group with Standard Adult Sized Laparoscopic Instruments
Authors: Gupta Sandeep , Khare Eeshansh , Pal Dilip Kumar
Published: February 2022

Most paediatric patients attend Urology Outpatient Department with diagnosis of pelviureteric junction obstruction. Now-a-days laparoscopic pyeloplasty is increasingly been used for the pelviureteric junction obstruction in paediatric patients. In the present case series, four paediatric patients of pelviureteric junction obstruction with age group of six, seven, eight and 12 years underwent laparoscopic pyeloplasty with adult sized laparoscopic instruments with ports size of 5 mm and 10 mm. Outcomes were measured in terms of mean operative duration, mean hospital stay and complications and improvement in Glomerular Filtration Rate (GFR). Mean operative duration was 211 min , mean blood loss of 96.25 mL and mean hospital stay was 5.75 days. Mean preoperative and mean postoperative GFR (at three months) were 53.19 mL/min and 55.35 mL/min respectively. In postoperative period one patient had increased drain output of more than 250 mL up to postoperative day three. All four patients had minor complications like postoperative fever on postoperative and ileus which were managed conservatively. Mean postoperative follow up duration was six weeks when Double-J (DJ) stent was removed. All patients had good outcome in terms of being asymptomatic and decreased hydronephrosis on follow-up renal ultrasonography and increased function of operated kidney on renal scan at three months. Based on intraoperative and postoperative observations, adult sized laparoscopic instruments can be used with ease with changes in port position and length of instrument inserted , adult sized laparoscopic instruments can be a useful armamentarium for paediatric laparoscopic pyeloplasty in cases of unavailability or intraoperative instrumental damage.
Effect of Incisional Negative Pressure Wound Therapy Following Incisional Hernia RepairA Randomised Controlled Trial
Authors: Mondal Arindam , Ali Manwar S , Galidevara Indira , Arumugam Murugan
Published: February 2022

Introduction: Incisional hernia is one of the common complications following abdominal surgery in patients undergoing laparotomy. Various surgical procedures are performed by creating a potential space and placing a foreign body (mesh), which may render the wound susceptible for many postoperative complications. It is clinically important to evaluate the efficacy of Incisional Negative Pressure Wound Therapy (INPWT) in reducing wound complications. Aim: To compare the efficacy of INPWT dressing with traditional gauze dressing in reducing postoperative complications following meshplasty in incisional hernia repair. Materials and Methods: This was a hospital-based randomised controlled trial, conducted in the Department of General Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India, from October 2013 to July 2015. 64 consenting patients with incisional hernias undergoing meshplasty were included in this study. After being randomised into the two study groups, they had their postoperative wounds dressed with either INPWT (Group A) for five days, or traditional gauze (Group B) based dressings. Operative parameters like duration of surgery, type of dissection and type of skin sutures used were studied and analysed. Also, postoperative outcomes like Surgical Site Infection (SSI), seroma, duration of drain, hospital stay were analysed using Chi-square or Fisher’s-exact test. Results: Out of total 64 patients, there was a statistically significant reduction in the volume of drain (p=0.004) and duration of wound drainage (p=0.029) with the use of INPWT. There was also a reduction in the incidence of SSI (6.7% vs 17.6%) and seroma (6.7% vs 11.8%) and the duration of postoperative hospital stay (6.03±1.99 days vs 7.09±2.31 days) in the INPWT group, which were however not statistically significant. Age, comorbidities, Body Mass Index (BMI), duration of surgery, type of dissection and type of skin sutures were not found to have any effect on the parameters assessed. Conclusion: Incisional negative pressure wound therapy in postoperative wounds, following meshplasty for incisional hernia significantly reduces the volume and duration of wound drainage. It also reduces the incidence of SSI, seroma and the duration of hospital stay
Association of Severity of Coronary Artery Disease with Left Ventricular Diastolic Dysfunction among Diabetics with Stable Ischaemic Heart Disease: A Cross-sectional Study from Odisha, India
Authors: Mishra Sura Kishore , Santra Avradip , Mishra Trinath Kumar
Published: February 2022

Introduction: Ischaemic Heart Disease (IHD) is one of the most common co-morbidity among Indian population, so is Diabetes Mellitus (DM). IHD is associated not only with systolic, but also with Diastolic Dysfunction (DDFx) of Left Ventricle (LV). However, there is scarcity of data correlating the severity of Coronary Artery Disease (CAD) with LV DDFx. Aim: To assess the severity of CAD in diabetic stable IHD patients with normal LV systolic function (LV Ejection fraction ≥50%) and it’s association with degree of DDFx. Materials and Methods: A prospective cross-sectional study was conducted over a period of one year, in a tertiary care hospital of Odisha, India among diabetic stable IHD patients. Grades of DDFx were assessed among the study population, using Transthoracic Echocardiography (TTE). Subsequently, severity of CAD was assessed, using invasive Coronary Angiography (CAG) using The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score. Next, grades of DDFx were correlated with severity of IHD. Results: Among a total of 93 diabetic stable IHD patients with normal LV ejection fraction, 76.3% were males and the mean age was 60.7±8.9 years. Majority presented with chronic stable angina (59, 63.4%). Hypertension (50, 53.7%), followed by dyslipidaemia (36, 38.7%) and renal dysfunction (19, 20.4%) were the most common co-morbidities. Majority of patients had grade I (39.8%), followed by grade II (17.2%), and grade III (9.7%) DDFx. On invasive CAG, 39.8% had a SYNTAX score of ≤ 22, 36.6% had a score of 23-32, and 23.6% had a score of ≥33. Grades of DDFx were found to be significantly higher among the patients with greater SYNTAX score. Conclusion: Among diabetic stable IHD patients, greater the severity of CAD on CAG, higher were the grades of DDFx
The Relationship between Oral Microbiome and SARS-CoV-2
Authors: Alghamdi Samar
Published: February 2022

The oral microbiome represents an important part of the human microbiome. It has an important function to protect against the colonization of extrinsic bacteria, affecting systemic health. On the other hand, the most common oral diseases such as caries, gingivitis, and periodontitis, are based on microorganisms. After the gut microbiome, the oral microbiome is the second largest microbial population in the body. It has the potential to affect the onset and progression of a variety of localized and systemic disorders, including viral infections, especially those that enter the body through the oropharynx. Pandemics like SARS and coronavirus disease 2019 (COVID-19) have impacted negatively on economies and people around the world in recent years, making viral infection one of the most common and dangerous health problems. Despite being one of many respiratory viruses that use the oropharynx as their primary replication site, the novel pandemic human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19 disease has yet to be determined. PubMed, Medline, Google Scholar, Science Direct, Scopus, and Web of Science databases were among the search engines used up to December 1, 2021. For published data, search terms included 'Microbiome', 'COVID-19,' ' Oral Microbiome changes in COVID-19,' dysbiosis in COVID-19', or 'SARS-CoV-2'. This concise review aimed to see if there was a link between the oral microbiome and SARS-CoV-2.
Post-COVID- 19 Mucormycosis: A Review
Authors: Patil Hemant , Spoorthy Mamidipalli Sai
Published: February 2022

Background and Aims: After being affected by a severe second wave of COVID-19 with numerous cases and deaths, India is now facing new challenges due to the disease. One of these is the feared complication of rhino-orbital mucormycosis in post-infectious individuals. Case reports and research studies on this association are on the rise. Our goal is to conduct a comprehensive literature review to evaluate the distinctiveness of individuals with mucormycosis and COVID-19.

Methods: A literature search was done on the following databases: PubMed, Google Scholar, and Cochrane Library using the following keywords like COVID 19, Mucormycosis, Mucor, Novel coronavirus, and SARS CoV-2, a systematic.

Results: Studies have shown that history of diabetes mellitus and steroid treatments were the common possible factors for the increased post-covid-19 mucormycosis.  Hyperglycemia secondary to uncontrolled hyperglycemic states like DM and immunosuppression secondary to covid-19 infection, steroid use form a vicious cycle causing mucormycosis.

Conclusion: Increased incidence of mucormycosis in India post-COVID infection appears to be due to a triad of diabetes, irrational steroid use, and COVID-19 itself. To decrease the frequency of deadly mucormycosis in patients with COVID-19, all attempts should be made to preserve optimal sugar levels in the body, and the use of corticosteroids should be restricted and should be given as per recommended by ICMR.
Consequences of Organ Transplant in Donors and Recipients
Authors: Saha Soumi , Banait Shashank
Published: February 2022

Organ Transplant has developed marvelously at a rapid pace and has become a major lifeguard. It has increased the survival rate of patients but certain complications are worth not ignorance .They should be treated as soon as possible for betterment of lifestyle, which otherwise may land up in life threatening conditions. A combined multiorgan transplant may offer a lower rate of graft rejection and lesser dependence on immunosuppressants. After transplant course can be followed by a few complications that can be early, late, and severe. Nevertheless, keeping a watch , regular follow ups and managing can determine the post operative cause of graft rejection. However, there has been a major increase in the demand for potential organs which is unable to met with the limited supply of donors. This hassle has left more patients in the country helpless. The shortage of existing organ crisis has deprived a lot of people from leading a better life and that gave rise to life time dependence on costly medical procedures like dialysis. Implementation of certain procedures of awareness and educational approach to people, about donating more organs on their consent, rewarding a gift of life to the people in need. This review has jotted down a few complications , that can arise post operative from the donor and recipient point of view, alongside the benefits associated with it . There’s no doubt Organ Transplant is a boon and a curse, but it has increased the life style of patients, family and friends.
Hepatic Encephalopathy and Challenges in Elderly –An Updated Review
Authors: Bhutda Shricha , Bhutda Sakshi , Sharma Ritika , Kumar Sunil
Published: February 2022

Hepatic encephalopathy, a type of brain disorder induced by hepatic dysfunction and portal system blood starvation. HE is the serious consequence of chronic liver disease that causes changes in individual behaviour, awareness, perception, activity performed. Depending on the severity, this split in two types: covert hepatic encephalopathy and overt hepatic encephalopathy. Most often utilised criteria for rating HE are the West Haven criteria (WHC). Septicaemia, GI hemorrhage, diuretic overdose, and dehydration, these risk factors are for the hepatic encephalopathy. The diagnosis is primarily clinical, but there are other possible causes for the altered state of mind. These patients have the poorer results, drop standard of living, and elevated hospital care utilization, inflicting financial and emotional load on caregivers. Other possible causes for the change in behavior consciousness should be ruled out, therefore the diagnosis is mainly clinical. Other possible causes for the altered mental state have been ruled out therefore the diagnosis is mainly clinical. The three major HE types are as follows: Acute liver failure leads to type A HE. Portosystemic bypass/shunting causes Type B HE. Cirrhosis-related HE of type C. Ammonia cannot be removed effectively due to liver dysfunction portosystemic collaterals. As a result, increased the level of NH3 in blood plasma & breaches the BBB, resulting in brain damage edema. The patient's mental state, musculoskeletal system, and mood/behavior are all affected by the symptoms of HE. These symptoms might range in severity, but they can start highly light.
Risk Factors for Nearsightedness during early Life, Childhood and Adolescence
Authors: Sharma Prachi , Kher Praveena
Published: February 2022

Nearsightedness is an essential public health issue that affects people worldwide. Nearsightedness is becoming more common, posing a significant socioeconomic burden. High nearsightedness that worsens over time might result in sight-threatening ocular problems. As a result, it's critical to avoid early-onset nearsightedness from escalating to high pathological nearsightedness. According to recent epidemiological studies, increased outside time is a significant modifiable environmental component that prevents young children against nearsightedness: outdoor light intensity, chromaticity during the day, and Vit. D levels may all play a role in this protective effect. This article summarises the possible protective relation between outdoor duration and nearsightedness. In light of new research, various environmental risk factors like near-work activities, the season of birth, smoking habits in parents, and birth order are also explored. This will allow for the implementation of preventative measures such as health education. Nearsightedness has grown significantly more widespread in recent decades, with certain highly educated groups, like students of law and medical fraternity, having nearsightedness rates of up to 80%. An increase in the number of instances of a high level of nearsightedness has been seen, which corresponds to the growth in nearsightedness. Myopia is said to be caused by multiple etiologies , High nearsightedness in early life is associated with high nearsightedness prevalence later in adulthood. Environmental variables such as greater academic pressure, more desk vocations, and urbanisation may be major drivers in current school nearsightedness trends, as seen by the rapid growth in nearsightedness prevalence observed in several parts of the world.
A Rare Entity of Desmoid Tumour: A Review
Authors: Bhagwat Yash , Kediya Anup
Published: February 2022

Desmoid tumors are a rare monoclonal, fibrotic boom characterized by a variable and conventional scientific course. Desmoids are invasive and related to a high clot recurrence rate and no longer have cancerous activity. Desmoids are identified with the valuable resource of changes in the β-catenin gene  A.P.C.

There are many troubles regarding the appropriate cure for victims with desmoid tumors. Rema the debate still; the surgical cure is the clinical way, without multiplying and related with significant attribute loss.

Therefore, the software of a multifunctional examination with multimodality therapy sorts the foundation of care for these patients. Waiting possibly be the most fabulous administration in some asymptomatic patients

Patients with desmoids positioned at the mesentery or head and neck should showcase life-threatening troubles and choose more excellent aggressive therapy. This evaluation article describes cure preferences and administration techniques for sufferers with desmoid tumors with a middle of interest on advanced disease.

Postoperative radiotherapy reduces the nearby recurrence rate in situations of worried surgical margins. Because of the heterogeneity of the biological behavior of desmoids, including prolonged periods of constant ailment or spontaneous regression, therapy desires to be individualized to optimize nearby tumors to manipulate and retain patients' exceptional of life.

Desmoids are hence an amazing uncommon tumor thing. Desmoids manifest between the age of 15 and 60 years. Still, in unique at some factor of late puberty, along with the maximum age of 30 yrs. 2 different kinds of desmoid tumors are shown. Except for spreading desmoid tumor oocarnce, there is a high-quality relation of desmoids...It can be related to the potential of persistent liver tissue damage and contamination accompanied by the beneficial aid of liver resuscitation. Meiotically lively liver cells, covered thru another environment, is most probable susceptible to hereditary stability is lost, and most cancers development.
Transvaginal Sonoelastography on Benign Masses of Cervix
Authors: Pattabiraman Suhasini , Dhande Rajasbala Pradeep , Varma Amruta Dinesh , Mishra Gaurav
Published: February 2022

Cervix is the lowermost portion of the uterus. Benign pathologies of the uterus mostly occur in women falling under the conceptive age profile. Frequently exhibited symptoms are excessive bleeding, menorrhagia and pain during menstruation or coitus. Sonoelastography in comparison to the sonography alone is a rather recent development and is easily affordable and available. This makes it ideal for use as a first – look diagnostic tool to determine the nature of the cervical mass without unnecessary invasive or expensive examinations. There is an urgent need for early differentiation of benign masses from malignant ones as it impacts the type of treatment administered, its efficacy, prognosis, and lifestyle post-treatment. This review aims to evaluate the accuracy of transvaginal sonography in correctly diagnosing benign masses of cervix from malignancy, and thus gives an overview of the evolution of its application in routine clinical practice. As seen in the review, only studies performing strain elastography have been taken into consideration with strain ratio being a focal point as this is a quantifiable unit, used for measurement of tissue elasticity. This gives us comparable results regarding the diagnostic precision of transvaginal elastography in cervical masses. Gold standard is used is histopathological diagnosis.
Stigma Associated with Mental Health Problems: A Review
Authors: Kasturkar Pooja R. , Gawai Jaya , Sebastian Sr. Tessy , Gomase Kavita , Patil Manoj
Published: February 2022

Stigma is the negative attitude towards a distinguishing  negative trait or personal feature. Although there have been inflow of efficient and feasible mental health therapies and programs and medical advances, nothing could be effective to reduce stigma. Stigma results in negative outcomes including difficulties with employment, poor social life and a decreased quality of life and self-esteem. Health care professionals and community people have to raise voices against stigma. Effective way of tackling mental illness stigmas are speaking out freely about mental disorders, avoid self-stigma, avoid labeling and discrimination, avoiding   use of insolent language for mentally ill and  get proper treatment. Poor mental health literacy and stigmatizing attitudes towards mental illness is more among community members so there is need to prevent the mental illness stigma in community and educate the people regarding mental health and measures to tackle mental illness stigma.
Anti-VEGF Therapy in Ophthalmology
Authors: Sharma Aanchal , Banait Shashank
Published: February 2022

Angiogenesis is when the growth of new blood vessels occurs from the pre-existing vasculature, occurring in both healthy and pathological conditions.Usually, there is a balance maintained between angiogenesis regulators (angiogenesis promoting factors and angiogenesis inhibiting factors), but when this balance is lost, there is either too much or too little angiogenesis. VEGF (Vascular endothelial growth factor) and its receptor (VEGFR) are critical regulators of angiogenesis that promote it.It has been seen that it plays a significant role in the regeneration mechanism of blood vessels,  inflammation of body tissues, cancer states, and wound healing. Various pathological conditions show increased VEGF activity.Nowadays, there has been increased use of anti-VEGF drugs, which target the vascular endothelial growth factor and slow down its action. The application of this therapy in ophthalmology is also becoming wider and wider. The implications of anti-VEGF dungs are cancers, rheumatological disorders,  macular edema, various retinopathies, glaucoma, etc. 

Anti-VEGF treatment comprises of three main drugs, namely-Avastin, Lucentis, and Eylea. Their efficiency has been proven to be equal with varying manufacturing costs, packaging, and associated risks.These are the brand names for bevacizumab, ranibizumab, aflibercept, respectively, which have helped us achieve different milestones in treating all kinds of retinal diseases. Several other diseases like iris neovascularization, age-related macular degeneration (AMD), corneal diseases also have been treated using anti-VEGF drugs. Like all drugs,  anti-VEGF drugs also have some limitations and side effects, including short half-life, systemic side effects; therefore, the development of new drugs still goes on.
Antifungal Susceptibility Pattern of Candida albicans and Non Candida albicans Species Isolates at a Tertiary Care Hospital in India
Authors: Gupta Sanjo , Gadekar Hemant B.
Published: February 2022

Vulvovaginal candidiasis (VVC) is a widespread fungus that affects women of all ages. After bacterial vaginosis, vulvovaginal candidiasis is the second most prevalent cause of vaginitis, affecting 40% of women with vaginal discharge. Candida is a fungus that is one of the most common opportunistic fungi in humans. The samples were processed using standard Candida isolation techniques. Candida species were identified using germ tube tests and Candida agar media. On Mueller Hinton Agar (MHA) supplemented with 2 percent glucose and 0.5 g/ ml methylene blue dye, the disc diffusion method was employed to investigate antifungal sensitivity. Candida albicans was responsible for 42 (36.3%) of the 350 Candida isolates, followed by Candida glabrata (24.1%), Candida tropicalis (22.5%), Candida krusei (12.3%), and Candida parapsilosis (12.3%). (9.7 percent). With a sensitivity pattern of 106/116, amphotericin Bis is the most effective antifungal medication against Candida isolates (91.3 percent). The resistance to ketoconazole, on the other hand, was the highest (20.6 percent). In light of the rising tide of antimicrobial resistance to fungal medicines, the current study suggests that species-level identification of Candida isolates should be encouraged.
Assessment of 8-Hydroxy 2-Deoxyguanosine as Salivary Biomarker for Periodontitis Patients with or without Diabetes Mellitus
Authors: Kumar M. Ashwin Shravan , Jeevitha M. , Jayaraman Selvaraj
Published: February 2022

Aim: The aim of this study is to assess the levels of 8-hydroxy-2 deoxyguanosine as a salivary biomarker for periodontitis with or without diabetes mellitus.

Study Design: Cross-sectional study

Materials and Methods: 30 patients were included in the study and were categorised into three groups: periodontal health (Group a), patients with periodontitis without diabetes mellitus (Group b) and patients with periodontitis only (Group c). Unstimulated salivary samples were taken. The OHdG concentration was evaluated using Sandwich-enzyme linked immunosorbent assay by commercially available human OHdG 96 well ELISA kit. The data were statistically analysed by One-Way -ANOVA. The Newman-Keuls multiple comparison test was used to test the significance at the levels of p<0.05.

Results: Salivary OHdG concentration in periodontal health, periodontitis with diabetes mellitus (P+DM), Periodontitis only (P) were analysed.  Salivary OHdG concentration was found to be significantly higher (p<0.05) in periodontitis with diabetes mellitus (38±2.82 ng/L) when compared with periodontitis only (20.5±2.12 ng/L) and also when compared with healthy controls (11.5±2.12 ng/L).

Conclusion: Diabetic patients with periodontitis have increased 8 hydroxy 2 deoxyguanosine than non-diabetic counterparts. Thus salivary 8 hydroxy 2 deoxyguanosine is an effective non-invasive biomarker to assess periodontitis among patients.
Chemotherapy Induced Secondary Spontaneous Pneumothorax in a Female with Endometrial Cancer- A Case Report
Authors: Naik Srinivas , Mohammad Shazia , Acharya Sourya , Acharya Neema , Varma Anuj
Published: February 2022

Endometrial cancer is one of the leading causes of death in post- menopausal women. It has significant impact on mortality and morbidity of women in the post-menopausal age group often requiring Hysterectomy along with Chemotherapy. Chemotherapy can be used to treat endometrial cancer with hematogenous metastases. Chemotherapy induced secondary pneumothorax is a rare complication. We present a case of a 68-year-old female patient with endometrial cancer who had pulmonary metastasis and was subjected to carboplatin, paclitaxel-based chemotherapy. During the fourth cycle she developed tension pneumothorax. This case highlights the importance of knowledge of life-threatening complications of chemotherapy regimens, so that the treating of physician/oncologists are ready to tackle these anticipated conditions.
Knowledge and Applicational use of Modified Monomer Acrylic Denture Base Resin among Dental Practitioners: A Survey
Authors: Christopher Varusha Sharon , Reader Rakshagan V. , Jeevitha M. , Jeyaraman Selvaraj
Published: February 2022

Several modifications to the denture base PMMA resins have been tried in recent years to improve the physico-mechanical and biological qualities. Polymer and monomer alterations are two types of modifications that can be found. Advances in polymer science have resulted in innovative polymers with higher impact strength and fatigue resistance, high-impact polymers and fiber-reinforced polymers, for example. This survey tries to determine the level of knowledge and awareness on the applications of these modified monomers in acrylic denture base resin among dental practitioners.