bluuebunny/crossref_metadata_2025 huggingface dataset:
The System of the Criminal Code of the Russian Federation
Authors:   Ural State Law University named after V.F. Yakovlev, Schelkonogova Elena
Published: August 2023

Introduction. The relevance of the research topic is determined by the need to consider the Criminal Code of the Russian Federation as a system-based construct and its correlation with the category of the branch of criminal law. The paper explores the questions of whether these concepts are synonymous and what the difference is between them. The purpose of the work is to substantiate the thesis about the independent nature of the Criminal Code of the Russian Federation, its difference from other branches of criminal law, and the existence of its own system. The study of the General and Special Parts of the Criminal Code of the Russian Federation as the constituent elements of the system of the Criminal Code of the Russian Federation is carried out. Methods. The scientific analysis of the Criminal Code of the Russian Federation as a system is carried out using ontological and axiological approaches, the method of system analysis, as well as comparative legal and historical methods. As a result of the study, the author comes to the conclusion that the Criminal Code of the Russian Federation consists of a set of articles but not rules of law. The philosophical correlation of the norms of criminal law with the category of the singular allows concluding that it belongs to an independent system of the branch of criminal law.
The Formation of Strategic Directions for the Prevention of Drug Addiction Among Young People at the Present Stage
Authors:   Belgorod Law Institute of the Ministry of Internal Affairs of Russia named after I.D. Putilin, Sarychev Alexander , Karaulova Ekaterina ,   Belgorod State National Research University, Arkhiptsev Ivan ,   Belgorod Law Institute of the Ministry of Internal Affairs of Russia named after I.D. Putilin
Published: August 2023

Introduction. The current situation in the Russian Federation in the field of illicit trafficking and illegal consumption of narcotic drugs, as well as psychotropic substances, poses a serious threat to public health, the country’s economy, law and order, and state security. To date, there are problems both in the legislative framework related to the fight against drugs, and in the educational process of institutions of learning. In this regard, it is necessary to name the purpose of the study, which is to take urgent measures aimed at improving preventive work with young people. Methods. The study is based on such methods as logical, systematic, formal-legal, as well as the methods of analysis, synthesis and other methods of scientific knowledge. Results. On the basis of the study, it is revealed that to combat drug addiction among young people, it is necessary to form strategic directions for the prevention both in the legislative framework related to the fight against drugs and in the bringing-up process of educational organizations. Conclusions. To effectively combat this problem, it is necessary to pay special attention to preventive work. The implementation of such prevention is entrusted to the internal affairs bodies, the bodies and institutions (organizations) of the healthcare system, education, social protection, youth affairs, the commissions for minors and the protection of their rights, in whose activities numerous violations continue to occur that negatively affect the general state of the fight against drug addiction.
The Impact of the Court’s Inner Conviction on the Evaluation of Evidence: A Civilizational Approach
Authors:   Volgograd State University, Azarova Ekaterina
Published: August 2023

Introduction. In criminal proceedings, the inner conviction of the court has a direct impact on the evaluation of evidence. In criminal proceedings, the process of proof is of key importance at all stages of the proceedings. Evidence in the Russian criminal process means any information, the sources of their reception, as well as the methods of their detection, collection, fixation, and verification, based on and in accordance with criminal procedure law, to establish the circumstances in issue. The main condition for making a legal and reasonable decision in a court case is to establish the event that occurred as it actually took place. Therefore, it is important to use the institution of the discretion of the court as the basis for resolving court cases. The author in the paper sets the goal of the study, which consists of substantiating the impact of the court’s inner conviction on the evaluation of evidence. Methods. The methodological framework consists of the methods of historicism, systematicity, and comparative law. Results. The author’s position, justified in the work, is based on knowledge of the criminal process. Conclusions. As a result of the study, it has been revealed that the inner conviction of the court is considered as a moral guarantee of the administration of justice, acting as a determinant in making decisions in accordance with conscience and moral categories. The process of proof is the main one in relation to the formation of the inner conviction of the court. The reason for this kind of subordination is related to the dependence of the proof process on the parties to the criminal case. The judge evaluates the evidence based on the level of legal culture and his or her inner beliefs.
Using the Internet as an Aggravating Circumstance: Is It a Civilizational Transformation or Prejudices of the Past?
Authors:   Volgograd State University, Perekrestov Vadim , Dechert Andrey ,   Volgograd State University
Published: August 2023

Introduction. The paper discusses the current problems of modern criminal law concerning the introduction of some qualifying features that establish a special way of committing a crime on the Internet. The proposals aimed at introducing a new aggravating circumstance into Part 1 of Article 63 of the Criminal Code of the Russian Federation are substantiated: “the commission of a crime using information and telecommunication networks, including the Internet.” In this regard, the purpose of the study is the analysis of the impact of information technology on the stability of the development of society through the establishment of criminal law prohibitions. The question is raised about the goals and objectives of introducing new provisions of criminal law establishing enhanced criminal liability for crimes on the Internet. Methods. Using the comparative legal method of scientific research as the main one, the authors trace the development of theoretical and legislative ideas about the impact of information technologies on public relations, analyze controversial issues of modern criminal law science, clarify and correct previously formed positions on the need to introduce new elements of crime. Results. Based on the conducted research, the opinion is substantiated about the absence of a systematic approach in the formation of the norms of Articles 110 of the Criminal Code of the Russian Federation, 1281 of the Criminal Code of the Russian Federation, and 133 of the Criminal Code of the Russian Federation, taking into account the interpretation of the norms of the criminal law proposed by the authors. Conclusions. It is advisable to amend the Criminal Code of the Russian Federation by excluding the feature “using information and telecommunications networks, including the Internet” from the Special Part. In addition, to eliminate the contradictions caused by the provisions under consideration, Part 1 of Article 63 of the Criminal Code of the Russian Federation should be supplemented with “the use of information and telecommunication networks, including the Internet.” The authors conclude that the new sign of crime slows down the civilizational transformation of criminal law norms, which does not allow timely responses to the challenges of modern reality.
Analysis of the Influence of Abiotic Factors on the Development of Microalgae in the Hyperhaline Kuyalnyk Estuary (Ukraine, the Black Sea Northwestern Coast)
Authors: Shikhaleyeva G. M. , Ennan A. A.-A. , Tsarenko P. M. , Kiryushkina G. M.
Published: August 2023

Investigations were carried out in the ecosystem of the Kuyalnyk estuary during high water period in 2004-2007. Relationships between the species diversity
of microalgae and their quantitative characteristics (cell numbers and biomass) and abiotic factors, including hydrophysical (water temperature, transparency, and suspended matter content), meteorological (precipitation
sum), and hydrochemical (water salinity, the content of nitrogen, phosphorus, and silicon inorganic compounds, dissolved oxygen, readily oxidized organic matter, and pH) ones, were analyzed in different seasons. It has been shown that the biomass of microalgae in the Kuyalnyk estuary during vegetation season from April until October 2004-2007 correlated well with water level (r = -0.69) and water salinity (r = 0.71), and also with the content of mineral phosphorus (r =
0.77). The correlation with other abiotic factors was not so significant and depended on season.
Adaptation of Biological Cycles of Fishes in the Tendra, Yahorlyk Bays and Adjacent Waters of the Black Sea to Environmental Changes Related to Recent Climate Changes
Authors: Tkachenko P. V.
Published: August 2023

The article briefly describes the main changes of the meteorological processes in the considered region over the last 10 years as compared with the long-term meteorological data since 1950s. Adaptations of the biological cycles
of different fish species in the Tendra and Yahorlyk bays and adjacent waters of the Black Sea under the influence of climate changes over the last 10-30 years are considered. It was established that the most notable changes took place owing to changes of the thermal regime and wind activity. The appearance of new fish species in these water areas under the influence of weather conditions and increase
of the rare species occurrence are discussed.
Changes in Hormonal Status of Aboriginal Fishes under the Impact of Agricultural Runoffs
Authors: Potrokhov O. S. , Zinkovskiy O. G. , Khudiyash Yu. M. , Vodianitskiy O. M.
Published: August 2023

Changes of cortisol, triiodothyronine, and thyroxine content in the blood plasma of perch, ruff, rudd and bleak under the impact of agricultural runoff from the adjacent territories to the water bodies were studied. Under the long-term exposure to the contaminated water, the weight and size of fish their growth rates specimens significantly decreased. The hormonal responses to the polluted waters impact are species-specific and partly depend on the ecological features of the species. Under the chronic impact of the polluted water, the cortisol content in blood plasma decreases and triiodothyronine content increases as compared to the control. The fishes occurring in the surface water layers create the thyroxine reserve in blood, and fishes which prefer the near-bottom layers use it to increase the triiodothyronine content. After treatment of the fields close to the reservoir with pesticides, the ruff and rudd develop the active stress reaction, the cortisol and thyroxine content in blood significantly increases. According to the considered indicators, the bleak is the most resistant to agricultural runoffs or possesses the ability to avoid toxic water pollution.
Otredades Comunicologías de los sures
Authors: Contreras Baspineiro Adalid
Published: August 2023

Un emprendimiento como el que Adalid Contreras Baspineiro pone a consideración del lector, adquiere invalorable importancia en tanto retoma el impulso contestatario de las construcciones narrativas promotoras de la revalorización de la diversidad, como pilar esencial para la construcción de una teoría propia del estar en un entorno asediado por la vecindad de una catástrofe planetaria de la cada vez más próxima extinción de la especie de los sapiens, a causa de la perpetuación del modelo homocéntrico del desarrollo heredado de la modernidad capitalista con su discurso centrado en la prevalencia absoluta de la razón y la mirada lineal del progreso. Un aporte añadido por Contreras Baspineiro a sus textos, es que estos rehúyen el simplismo y la depreciación lingüística a la cual viene incitando la seudo comunicación a través de redes, plataformas y aplicaciones. Sus escritos, como los de Luís Ramiro Beltrán, Néstor García Canclini, Jesús Martín-Barbero y otros maestros con cuya obra resulta equiparable la del autor, nos dan la magnífica oportunidad de adentrarnos en una recopilación imperdible por su alcance provocador al desentrañamiento de los nudos conceptuales que mantenían blindada la teoría de la comunicación al más mínimo cuestionamiento de sus premisas.
A checklist of the dacine fruit flies (Diptera, Tephritidae, Dacinae) of Mozambique
Authors: De Meyer Marc , Bota Luis , Daniel Beatriz , Mussumbi Mirene , Vandenbosch Myriam , Canhanga Laura , Cambula Elias , Mansell Mervyn , Cugala Domingos , Virgilio Massimiliano
Published: August 2023

Here we present a checklist of all records of dacine fruit flies (Diptera: Tephritidae: Dacinae) from Mozambique, based on verified specimen records in natural history collections and literature records. In total, 57 Dacinae species are recorded from Mozambique, of which only one is considered endemic. This relatively low species diversity compared to other African countries appears to be related to incomplete sampling. For each species the localities from which it was recorded are given (including geocoordinates), or a general distribution is provided. The checklist is discussed briefly in terms of species richness, endemism and geographic distribution.
Mitophagy induction using Oligomycin/Antimycin A v1
Authors: Uoselis Louise
Published: August 2023

Mitophagy induction in HeLa cells using Oligomycin/Antimycin A.
qRT-PCR sample preparation v1
Authors: Uoselis Louise
Published: August 2023

Protocol for qRT-PCR sample preparation for analysis using a RotorGeneQ machine (Qiagen).
Measuring mitophagy via FACS with mtKeima reporter v1
Authors: Uoselis Louise
Published: August 2023

Preparation of samples for measuring mitophagy levels using mtKeima reporter by fluorescence activated cell sorting (FACS).
Inducing proteostasis stress using G-TPP v2
Authors: Uoselis Louise
Published: August 2023

Inducing proteostasis stress in HeLa cells with G-TPP to analyse proteostasis protection and repair.
Western blotting using the BioRad Criterion Blotter system v1
Authors: Uoselis Louise
Published: August 2023

Protocol for performing an SDS-PAGE Western blot analysis using the BioRad Criterion Blotter system.
Miltenyi Biotec: Adipose Tissue Dissociation -- University of Minnesota TMCs v1
Authors: Biotec Miltenyi
Published: August 2023

Dissociation of human adipose tissue using Miltenyi dissociation kit Catalog #130-105-808 and Protocol #140-004-708.02
Preparing mitochondrial samples for immunoblot analysis v1
Authors: Uoselis Louise
Published: August 2023

Protocol for preparation of mitochondrial samples for immunoblot analysis.
Mitophagy induction using Difereprone v1
Authors: Uoselis Louise
Published: August 2023

Mitophagy induction in HeLa cells using Difereprone (DFP).
Reverse-phase high pH fractionation (using Thermo Fisher, Cat# 84868) v1
Authors: Uoselis Louise
Published: August 2023

This protocol uses the Pierce™ High pH Reversed-Phase Peptide Fractionation Kit (Thermo Fisher, Cat# 84868)
Left atrial myxoma — difficulties in diagnosis, determination of treatment tactics in an older patient: clinical case
Authors: Alekseeva Sofya V. , Liseev Alexey A. , Tretyakova Natalya S.
Published: August 2023

BACKGROUND: Myxoma is one of the most common benign neoplasms of the heart. The most characteristic localization is the inter-atrial septum in the region of the oval window. Clinically, myxoma can be represented by obstructive, thromboembolic, non-specific symptoms. However, the absence of pathognomonic signs is the reason for the late diagnosis and treatment.
CLINICAL CASE DESCRIPTION: A 78-year-old female patient was hospitalized at the department of cardiology for examination, correction of therapy, and determination of indications for diagnostic coronary angiography. During a routine examination, echocardiographic data revealed a formation in the left atrial (LA) cavity. To clarify the diagnosis and determine the treatment strategies, the patient underwent magnetic resonance imaging of the heart with gadolinium, which verified this formation as an LA myxoma measuring 1012 mm. Considering the age of the patient, the presence of concomitant pathology, and absence of complications of myoxoma (obstructive and thromboembolic), the patient was further observed.
CONCLUSION: LA myxomas have clinical manifestations; however, quite often, they are accidental findings in echocardiographic studies. Surgical removal of the tumor is currently the main treatment method. The absolute indications for surgical treatment are large tumors and presence of complications (embolic and obstructive). However, in older patients, who, according to imaging methods, have small tumors and concomitant somatic diseases, dynamic follow-up appears suitable to assess the progression of tumor growth and determine the timing of surgical treatment.
Spontaneous anterior coronary interventricular artery dissection in a young woman in the late postpartum period: clinical case
Authors: Anokhina Alena R. , Matyushin Gennady V. , Ustyugov Sergei A. , Kharkov Evgeny I. , Savchenko Elena A. , Vlasov Petr N. , Okhrimchuk Vadim V. , Skorobogatov Valentin V. , Popova Ekaterina V. , Karaev Elnur B. , Tsibulskaya Natalya Yu. , Ryabkov Evgeny I.
Published: August 2023

BACKGROUND: Cardiovascular complications during pregnancy and postpartum period are rare but often fatal. The causes and mechanisms of the development of such complications are not fully understood. Spontaneous dissection of the coronary artery against the background of the influence of sex hormones is one of the mechanisms for the development of acute coronary syndrome in the postpartum period. The false lumen of the intramural hematoma overlaps the true lumen, causing arterial obstruction, leading to acute myocardial hypoxia. Thus, awareness that the pathophysiology of spontaneous coronary artery dissection differs from that of acute coronary syndrome associated with atherosclerotic plaque rupture is important, and these patients require different treatment approaches. Currently, an unambiguous and precise strategy for this pathology has not been established, which is why difficulties remain in the management of these patients and choosing treatment strategies.
CLINICAL CASE DESCRIPTION: The article describes a complex clinical case of the development of acute myocardial infarction in the postpartum period in a young woman without risk factors against the background of spontaneous dissection of the coronary artery, complicated by cardiogenic shock, which required emergency percutaneous coronary intervention and stenting of the infarct-dependent artery. The postoperative period proceeded with complications, and extracorporeal membrane oxygenation was required. However, an integrated approach and correctly chosen treatment strategies help stabilize the patients condition.
CONCLUSION: Currently, no unambiguous and precise strategy of treatment has been established, so difficulties remain in the management of patients and decision making. In our opinion, an individual patient approach should be followed, taking into account the general state of the organism, type and volume of dissection, consequences and complications, and experience and technical capabilities of the clinic.
Educação Matemática Inclusiva: o que Mostram as Pesquisas Publicadas Entre 2013 e 2018 em Periódicos com Qualis em Ensino
Authors: Morás Nadjanara Ana Basso , Antunes Francieli Cristina Agostinetto , Nogueira Clélia Maria Ignatius
Published: August 2023

Nos últimos anos, o número de alunos apoiados pela Educação Especial que frequentam a escola regular comum cresceu significativamente, como apontado pela Política Nacional de Educação Especial na Perspectiva da Educação Inclusiva. Crescimento perceptível, também, quando analisadas as publicações acerca de Inclusão dos alunos no sistema educacional em periódicos da área de Ensino. Esses aumentos motivaram este estudo, que teve como objetivo identificar quais níveis de ensino e quais deficiências têm sido foco das pesquisas em Educação Matemática Inclusiva. Realizou-se uma pesquisa bibliográfica em periódicos com Qualis A1, A2 e B1 em Ensino, exclusivamente, de artigos que interessam à Educação Matemática Inclusiva, publicados entre os anos de 2013 e 2018, buscando o termo ‘inclusão’ nos títulos, resumos e palavras-chave. Por meio dessa análise, constatamos que as pesquisas foram levadas a cabo em diferentes níveis de ensino, com exceção da Educação Infantil, e têm maior concentração nos níveis da Educação Básica, anos iniciais e finais do Ensino Fundamental (antes chamados de Ensino Fundamental I e II). Além disso, verificamos que grande parte das pesquisas tinham como objetivo estudar a surdez e a baixa visão ou cegueira.
Palavras-chave: Inclusão. Educação Matemática. Educação Especial. Níveis de Ensino.
AbstractIn recent years, the number of students supported by Special Education who attend common regular schools has grown significantly, as pointed out by the National Policy on Special Education from the Inclusive Education Perspective. A growth that is noticeable too, when analyzing publications about the Inclusion of students in the educational system in journals on the field of Education. These increases motivated this study, which aimed to identify which levels of education and which disabilities have been the focus of research on Inclusive Mathematics Education. A bibliographic research was carried out in journals with Qualis A1, A2, and B1 in Teaching, exclusively, of papers which concern Inclusive Mathematics Education, published between 2013 and 2018, searching for the term 'inclusion' in its titles, abstracts, and keywords. Through this analysis, we were able to find that the research was carried out at different levels of education, except for Early Childhood Education, and has a greater concentration on the levels of Basic Education, initial and final years of Elementary School (previously called Elementary School I and II). Additionally, we found that most of the research aimed to study deafness and low vision or blindness.
Keywords: Inclusion. Mathematics Education. Special Education. Levels of School Education.
As Origens do Estudo Dirigido
Authors: Santana Rogério Joaquim
Published: August 2023

Esse artigo é parte de uma pesquisa exploratória ainda em curso, estritamente bibliográfica sobre as origens da atividade do Estudo Dirigido (ED). Por meio de referências em artigos e livros brasileiros, produzidos pela Campanha de Aperfeiçoamento e Difusão do Ensino Secundário (CADES) que tratam do ED, procuramos indícios de suas origens a fim de fazer a reconstituição da sua origem no início dos anos 1900 até as sugestões dos autores e professores que defendiam sua aplicação nas formações de professores e nas salas de aula até meados de 1970. Até o momento da confecção desse artigo apuramos que o ED, teve muitas interpretações e distorções discutidas neste artigo e ainda carecem de novas pesquisas para melhor compreensão do Estudo Dirigido.
Palavras-chave: Estudo Dirigido. Método de Ensino. História da Educação Matemática.
Abstract This article is part of an ongoing exploratory research, strictly bibliographical, on the origins of the Directed Study (ED) activity. Through references in Brazilian articles and books, produced by the Campaign for the Improvement and Diffusion of Secondary Education (CADES) that deal with DE, we look for evidence of its origins in order to reconstitute its origin in the early 1900 s to the suggestions of the authors and teachers who defended its application in teacher training and in classrooms until the mid-1970 s. Until the writing of this article, we verified that the DE, had many interpretations and distortions discussed in this article and still lack new research to improve it. understanding of Directed Study.
Keywords: Directed Study. Teaching Method. History of Mathematics Education.
Valued and Valuing Globality
Authors:   University of Wrocław, Institute of Cultural Studies, Poland Poland, Nobis Adam
Published: August 2023

The aim of the article is to analyze the connections between understanding and evaluating globality. The analysis employs the conception of the axiosemiotic sphere developed by Stanisław Pietraszka. According to this conception, meanings enable the expression of values and values enable the valorization of meanings. I analyze selected examples of understanding and evaluating globality from various discourses: scientific, corporate, journalistic, journalistic, religious, and curatorial. I come to three conclusions. The first: the links between meanings and values entail that the change of meanings is accompanied by a change of values and the change of values is accompanied by a change of meanings. Second: meanings not only express values but also determine each other’s content. Thus, changing one meaning changes other meanings. Third: values not only valorize meanings, but they valorize each other, determining their valence. And so, globality is sometimes valorized with other values, but in other situations it becomes the basis for evaluation itself. There are also contexts in which globality and other values valorize each other, determining their valence.
Pengaruh Blended Learning Enriched Virtual Model Terhadap Hasil Belajar Materi Konflik Sosial Di SMA
Authors: Djagom Donatus , Kuswandi Dedi , Praherdhiono Henry
Published: August 2023

To keep up with the latest developments in science and technology, schools must use teaching strategies that are in line with modern times. One of them is the Blended learning Enriched Virtual Model (BLEV), which is a mixed model that is enriched through features in Google Classroom for learning needs. To test this model with social conflict material, the experimental group applied the model and the control group. Quantitative approaches and quasi-experimental procedures are used to explore the effect of one on the other under controlled conditions. The results showed that there were differences between the two groups. According to this study, students who use the virtual mixed learning model have superior learning outcomes than the traditional mixed learning model. It has also been shown that using an enriched virtual blended learning paradigm can expose students to the topic of social conflict. Therefore, the use of an enhanced virtual blended learning paradigm is highly recommended for students, especially in social conflict content.AbstrakUntuk mengikuti perkembangan ilmu pengetahuan dan teknologi terkini, sekolah harus menggunakan strategi pengajaran yang sesuai dengan zaman modern. Salah satunya adalah Blended learning Enriched Virtual Model (BLEV) yaitu sebuah model campuran yang diperkaya melalui fitur-fitur di Google Classroom untuk kebutuhan pembelajaran. Untuk menguji model tersebut dengan materi konflik sosial, maka kelompok eksperimen menerapkan model tersebut dan kelompok kontrol. pendekatan kuantitatif dan prosedur kuasi-eksperimental digunakan untuk mengeksplorasi pengaruh satu terhadap yang lain dalam keadaan terkendali. Hasil penelitian menunjukkan bahwa ada perbedaan antara kedua kelompok tersebut. Menurut penelitian ini, siswa yang menggunakan model pembelajaran campuran virtual lebih unggul hasil belajarnya daripada model pembelajaran campuran tradisional. Juga telah ditunjukkan bahwa menggunakan paradigma pembelajaran campuran virtual yang diperkaya dapat memaparkan siswa pada topik konflik sosial. Oleh karena itu, penggunaan paradigma blended learning virtual yang disempurnakan sangat dianjurkan bagi siswa, terutama pada konten konflik sosial.
Analisis Persepsi Mobile Learning Readiness Dengan Menggunakan Technology Acceptance Model Dalam Pembelajaran Bahasa Jawa
Authors: Pangestu Sulih Aji , Setyosari Punaji , Kuswandi Dedi
Published: August 2023

Technological developments in the current era are growing rapidly. Disruptive innovation from this technological development penetrates human needs in various fields, especially in the field of education. Regulations on technological developments in the field of education become learning innovations to remain effective and efficient in their utilization. The application of Mobile Learning requires a readiness analysis that must be considered from the Perceived Ease of Use and Perceived Usefulness variables. This research is an exploratory study with the technology acceptance model (TAM). The aim is to find out the extent of the level of acceptance of the use of media, especially at the junior high school education level. In the acquisition of overall results data reviewed from several aspects namely Student Readiness, Perceived Ease of Use and Usefulness get very good acceptance from the learners. It is proven that the use of media can be accepted by learners who are in accordance with the needs. Furthermore, it is important for educational institutions and teachers to pay attention to learners' perception of Ease of Use and Usefulness on the use of Mobile Learning. Proper support and provision of relevant and useful content can help learners' readiness level in adopting and utilizing Mobile Learning effectively in the learning process.AbstrakPerkembangan teknologi pada era sekarang yang semakin berkembang pesat. Inovasi secara disrupsi dari perkembangan teknologi ini merambah pada kebutuhan manusia dalam berbagai bidang khususnya dibidang pendidikan. Regulasi pada perkembangan teknologi dalam bidang pendidikan menjadi inovasi pembelajaran agar tetap efektif dan efisien dalam pemanfaatannya. Penerapan Mobile Learning ini membutuhkan analisis kesiapan yang harus diperhatikan dari variabel Perceived Ease of Use dan Perceived Usefulness. Penelitian ini merupakan penelitian eksploratif dengan model penerimaan teknologi (TAM). Tujuan untuk mengetahui sejauh mana tingkat penerimaan pada penggunaan media khususnya di tingkatan pendidikan Sekolah Menengah Pertama. Pada perolehan data hasil keseluruhan ditinjau dari beberapa aspek yakni Student Readiness, Perceived Ease of Use dan Usefulness mendapatkan penerimaan yang sangat baik dari para pebelajar. Hal ini terbukti bahwa penggunaan media dapat diterima oleh pebelajar yang sesuai dengan kebutuhan. Selanjutnya penting bagi institusi pendidikan dan pengajar untuk memperhatikan persepsi pebelajar tentang Ease of Use dan Usefulness pada penggunaan Mobile Learning. Dukungan yang tepat dan penyediaan konten yang relevan dan bermanfaat dapat membantu tingkat kesiapan pebelajar dalam mengadopsi dan memanfaatkan Mobile Learning secara efektif dalam proses pembelajaran.
Drivers of Student Technology Readiness in Using Cloud Accounting to Improve Student Performance
Authors:   the Department of Accounting, Universitas Negeri Jakarta, Indonesia, Musyaffi Ayatulloh Michael , Oli Mario Colega , Afriadi Bambang
Published: August 2023

Cloud technology can make the learning process easy and done anywhere. However, in its use, some students feel anxious and prefer learning using offline software. This research targets students in Indonesia who study cloud accounting in computer accounting courses and introductory accounting. Researchers used the census method to get respondents, so a sample of 131 respondents was obtained. The incoming data is then tested for validity and reliability using PLS (partial least square) with the help of smartpls 3.0. After that, an analysis of technology readiness was carried out using technology readiness index (TRI), which consisted of optimism, innovativeness, insecurity, and discomfort. The results show that most students have medium technology readiness, with motivational factors such as optimism and innovativeness having a very high category. At the same time, the inhibiting factors in adopting technologies such as insecurity and discomfort are in the medium category. Most students also have the characteristics of explorers who like new technology, so cloud accounting is welcomed with great enthusiasm. However, based on the characteristics of male and female students, the technological readiness of male students is better than that of female students. One aspect that is lacking is the aspect of insecurity. Female students are worried when the assignments given do not reach their lecturers. So, cloud accounting service providers should provide an ecosystem that can facilitate all students. In addition, the findings of this study can also be helpful for lecturers to carry out learning by looking at the TRI from students so that learning can be more effective.
Production Model to Increase the Level of Order Fulfillment through the Implementation of Lean Tools and Ergonomics in SMEs of the Textile Sector
Authors:   Facultad de Ingeniería, Universidad de Lima, Perú, Rafael-Abad Antoni , Ancalle-Polanco Alexis , Quiroz-Flores Juan Carlos , Collao-Diaz Martin , Flores-Perez Alberto
Published: August 2023

This research work was born from a common problem in most textile manufacturing companies, which is the non-fulfillment of orders. A Peruvian textile manufacturing company dedicated to the production of baby clothes was taken as a case study. In this case study, an in-depth diagnosis will be carried out to identify the causes that lead to the company's inability to fulfill orders on the defined dates. Once the causes have been identified, we will proceed to evaluate the methodologies to be implemented to increase the order fulfillment indicator. The most relevant indicators to know if the objective for which the research was carried out was met are order fulfillment, which the current KPI was 71.31% and with the improvement turned out to be 81.32%; machine availability, which the initial diagnosis was 81.5% and the final diagnosis was 89.28%; efficiency in the ironing area, which started with 87.88% and ended with 92%; and finally the percentage of a defective product, which started with 10% in the stamping area and 12% in the cleaning area and ended with 5% in both areas.
Assessing the Major Aspects and Implications of Telerehabilitation Services: A Bibliometric Analysis
Authors: Alyacoubi Osama Khalil , Ulfa Maria , Dewi Arlina
Published: August 2023

Telerehabilitation has emerged as a promising option for delivering rehabilitation services to individuals with physical impairments, but its effectiveness, efficiency, and economic implications are not yet fully understood. This study explores the relationship between telerehabilitation services and various aspects of healthcare delivery, including treatment, quality, outcome, and delivery of telerehabilitation. The Scopus database (https://www.scopus.com) with the term "Telerehabilitation Services" from 2012 to 2021 was used to gather the most recent evidence for this type of research: qualitative research on telerehabilitation services. Studies reporting on clinical outcomes and delivery of healthcare topics were included in the selected publications. VOSviewer, MAXQDA Analytic Plus, and Nvivo 12 Plus analytical tools assisted data analysis and extraction procedures. The findings indicated that telerehabilitation directly impacts health, with a very strong correlation value of 0.962644. Therapy, Aged, Stroke, Telemedicine, COVID-19, Treatment, Quality, Outcome, and Delivery also showed a strong correlation ranging from 0.851146 to 0.921129. Telerehabilitation services had a significant relationship with technology, physiotherapy, and feasibility, with a correlation ranging from 0.427715 to 0.572538. Challenges include the need for appropriate technology and infrastructure, data privacy and security concerns, and the potential for technology-related errors. Telerehabilitation significantly influenced healthcare delivery, including stroke, COVID-19, treatment, quality, outcome, delivery, technology, physiotherapy, and feasibility. Challenges remain, and further research is needed to evaluate cost-effectiveness in different settings and populations. Technology can enhance patient outcomes with proper planning, training, and support.
A study on clinical and arterial blood gas parameters before and after tube thoracostomy among cases of primary and secondary spontaneous pneumothorax
Authors: Sen Subhajit , Kundu Somenath , Chatterjee Surajit
Published: August 2023

Pneumothorax is a common respiratoryemergency that requires active interventions in many cases specially Tube thoracostomy. Objective of the present study is to find out changes in clinical and arterial blood gas parameters in primary and secondary pneumothorax following tube thoracostomy at different time intervals.

Total 30 cases, Primary spontaneous pneumothorax (PSP) 11 and secondary spontaneous pneumothorax (SSP) 19. Clinical parameters: pulse rate, blood pressure, respiratory rates, oxygen saturation (SpO2).

ABG analysis: pH, partial pressure of carbon dioxide (pCO2), partial pressure of oxygen (pO2), AaDO2. Time interval: pre tube thoracostomy, 1hour and 24hours after thoracostomy and after tube removal.

PSP was found more in young patients (mean 34.18), SSP in older patient (mean 52.68), (P=0.001). Among clinical parameters statistically significant changes were seen in pulse rate, (P<0.001) respiratory rate (P<0.001) in both groups, in both cases tachycardia and tachypnea decreased. Diastolic blood pressure in SSP group (P<0.01), SO in SSP group (P<0.05). There is an increase in mean arterial pressure from pre thoracostomy compared to in 1hr, 24hr and at removal. Which statistically significant in SSP group.

In PSP group hypoxaemia was present in 54.54% patients before giving chest tube, after 1 hour of tube thoracostomy only 18.18% cases had mild hypoxaemia. In SSP group 68.42% cases presented with hypoxaemia initially, after tube removal 26.31% cases had mild hypoxaemia.No significant changes in other blood gas parameters were seen in either groups.

The impact of tube thoracostomy on primary and secondary pneumothorax are mainly reflected on clinical parameters rather than blood gas parameters.
Recursos para impugnar autos en la fase intermedia del proceso penal: ¿por qué son importantes?
Authors: Espinosa Molina Jonathan Israel
Published: August 2023

El presente artículo analizará la posibilidad de agregar un recurso idóneo y eficaz que revea los errores que pueden ocurrir durante la etapa intermedia del proceso penal en específico dentro de los autos de llamamiento a juicio, de sobreseimiento sin acusación fiscal y el de exclusión probatoria. De esta manera, se analizará que los autos mencionados son trascendentales dentro del proceso penal ecuatoriano, por lo que contar con un recurso que revea los vicios adjetivos y sustantivos son imperativos para prevenir vulneraciones a los derechos de las partes y garantizar una mejor tramitación de la justica.
Neuroprotective Effects of Isolated Fraction from Sapindus laurifolia Extract in Hippocampal Neuronal HT22 Cells
Authors: Bandaru Nagaraju , Ramu A. , Vidhyadhara S.
Published: August 2023

Glutamate is a major endogenous excitatory neurotransmitter in the brain and contributes to the development of neurodegenerative diseases by excessive activation. The purpose of the present study was to determine the neuroprotective effect of Sapindus laurifolia (MESL) Fraction A against glutamate-induced oxidative stress and to assess the underlying mechanism. MESL Fraction A was subjected to a neuroprotective effect assay in HT22 mouse hippocampal cells. The mechanism underlying the neuroprotective effect of MESL Fraction A was evaluated by assaying Reactive Oxygen Species (ROS) levels, intracellular Ca2+ levels, mitochondrial membrane potential and glutathione level and antioxidant enzyme activity in HT22 cells. MESL Fraction A significantly decreased glutamate-induced death of HT22 cells (88.23 ± 1.65% relative neuroprotection). MESL Fraction A reduced the intracellular ROS and Ca2+ levels and increased the glutathione level and glutathione reductase and glutathione peroxide activities. Moreover, MESL Fraction A attenuated the mitochondrial membrane potential in HT22 cells. These results suggested that MESL Fraction A exerts a neuroprotective effect against oxidative stress HT22 cells, which was mediated by its antioxidant activity.
Neuroprotective Potential of Bacopa monnieri, Camellia sinensis and Curcumin on Chlorpyrifos Exposed Drosophila melanogaster
Authors: Pratap Singh Mahendra , Hamid Humera , Himalian Ranjana
Published: August 2023

The popular treatment approaches of neurodegenerative diseases are generally for symptom management, but unfortunately, there is no significant curative approach present so far that can signifcantly reduce its progression. Indian traditional medicine is being used alone or in a combination of herbs to fight against these diseases. The commonly used herbs/traditional medicine(s) for this purpose are Bacopa monnieri (Brahmi), Curcuma longa (curcumin) and Camellia sinensis (green tea). In the present study, herbs were judged for its free radical scavenging activity through DPPH free radical scavenging assay, Total Phenolic Content (TPC) and also Total Flavonoid Content (TFC). Among them, green tea exhibited highest total phenolic content and also higher total flavonoid content (99.667±3.547 mg GA/g and with 7.633±2.532 mg QE/g, respectively) followed by Bacopa monnieri and Curcumin. In this context, Green tea showed maximum free radical scavenging activity than curcumin followed by Brahmi (GT>CUR>BM). These herbs were evaluated to check their potential in the improvement of the climbing ability of flies and acetylcholinesterase enzyme activities using Drosophila melanogaster (fruit flies). In this study, fruit flies were fed normal food, chlorpyrifos contaminated food and also chlorpyrifos (Chlor) along with individual herbs as mentioned above (Chlor+GT, Chlor+CUR, Chlor+BM). Interestingly, we found that the free radical scavenging activity and antioxidant activities, of Brahmi (97%) has the highest improvement in climbing activity as compared to green tea (90%) followed by curcumin (86%) and organisms treated with these herbs show a trend BM>GT>CUR. Moreover, Brahmi also exhibited maximum improvement in AChE activities as compared to curcumin and green tea and showed a trend BM>CUR>GT.
Bio-Antioxidants Protect the Buffalo Bone Marrow Derived Mesenchymal Stem Cells against Oxidative Stress Induced During Freeze-Thaw Cycle
Authors: Kaur Navjot , Sharma M. , Lonare M. K. , Udehiya R. , Singh D.
Published: August 2023

The present investigation was planned to evaluate the effect of curcumin (CUR) and resveratrol (RES) on oxidative stress indicators (LPO, O2- radical, ROS and TPC), antioxidant status (GSH, GPx, SOD, CAT and GST) and cytotoxicity markers (ALP, LDH, GGT and CK-MB) in mesenchymal stem cells (MSCs) derived from buffalo bone marrow during the freeze-thaw cycle of one month. MSCs were isolated and cultured in high glucose DMEM supplemented with 15% FBS. MSCs were found to be positive for alkaline phosphatase (AP) activity and stem cell markers (CD73 and OCT4). Results revealed a significant reduction in (pâ‰¤0.05) in oxidative stress parameters and cytotoxicity markers, while, the levels of cellular antioxidants were found to be significantly increased (pâ‰¤0.05) in CUR/RES alone and in combination groups as compared to the control group. In conclusion, the addition of bioantioxidants in the cryopreservation medium has improved the post-thaw cell recovery through suppression of oxidative stress-induced during the freeze-thaw cycle.
Toxicological Evaluation of the Repeated Dose Administration of the Ethanolic Extract of Azolla microphylla in Wistar Albino Rats
Authors: Kunnathupara Bhaskaran Sreenath , Kannappan Poornima , Muneeswari Perumalsamy , Madathil Rashmy
Published: August 2023

Azolla microphylla is an easily cultivable aquatic plant with the commendable nutritious property. Recent reports on Azolla species emphasize the therapeutic potential of the plant extracts. Moreover, the same genus of plant also had displayed antioxidant potential owing to its free radical scavenging tendency. Although these attributes were identified, a study investigating the toxicological property of different dosages of ethanolic extract of A. microphylla (EAM) is not yet reported. Thus the present study aims for the in vivo toxicological evaluation of the EAM in Wistar strain of rats. Daily doses of 0, 250, 500, 1000 and 2000 mg/kg body weight of EAM were administered orally to group-I, group-II, group-III, group-IV & group-V rats, respectively for 14 days. Biochemical and histopathological studies were established through standard methods. The acute toxicity results suggest the non-toxic nature of the extract supported with the absence of mortality and toxic symptoms until 72 h of observation. The results of sub-acute toxicity study in the extract-treated rats (group-II to group-IV) indicate non-significant changes to the biochemical (total protein, AST, ALT, LDH, albumin, globulin, urea, creatinine, cholesterol, & triglycerides), hematological (Hemoglobin, RBCs, WBCs, platelets, monocytes, lymphocytes, & neutrophils), and histopathological observations when compared to the control group of rats. However, group-V rats were treated with 2000 mg/kg b.w. exhibited statistically significant variations to most of the biochemical and hematological parameters although no mortality/physical toxic signs were reported till the end of the experimental period. Thus, the sub-acute toxicity results suggest that the extracts were non-toxic and safe to rats between 250-2000 mg/kg b.w. concentration under 14 days observational period. Moreover, as there was no mortality upto 2000 mg/kg b.w., 50% lethal dose (LD50) could not be determined, and hence it is considered to be greater than 2000 mg/kg/day.
Protective Effects of Quercetin against Rotenone Induced Histopathological and Biochemical Alteration in Testes of Mice
Authors: Jain Juli , Hasan Whidul , Singh Yadav Rajesh , Jat Deepali
Published: August 2023

The present work aimed to investigate the protective role of quercetin against rotenone-induced testes damage at the level of oxidative stress and histological alteration. Reproductive toxicity was induced in mice by oral treatment of rotenone, 5 mg/kg body weight daily for 60 days, dissolve in sunflower oil as a vehicle. The quercetin was orally administered 30 mg/kg body weight daily for 60 days along with rotenone. The results of the current study showed that rotenone significantly reduced the Reduced glutathione (GSH) content and decreased the activities of Catalase (CAT) and Superoxide dismutase (SOD) and increased the oxidative markers such as Lipid peroxidation (LPO), and Nitric Oxide (NO) in rotenone treated group as compared to control. Co-administration of quercetin along with rotenone significantly reduced LPO and NO in the testes of mice when compared to rotenone alone group, increased the content of GSH, enhanced activities of CAT, and SOD when compared to rotenone the only group. The results of histological studies of the rotenone treated group showed a reduced number of germ cells, sperms loss, abnormality in seminiferous tubules, and degeneration of interstitial cells was found in the rotenone treated group as compared to control. While co-administration of quercetin reverses these adverse effects. The results of the current study clearly indicated that rotenone exerts harmful effects on the testes and co-administration of quercetin along with rotenone significantly protects damage caused by rotenone.