bluuebunny/crossref_metadata_2025 huggingface dataset:
MOLECULAR DOCKING AND BIOLOGICAL ACTIVITY OF N- (4-METHOXY)-BENZOYL-N’-PHENYLTHIOUREA AND N-(4- TRIFLUORO)-BENZOYL-N’-PHENYLTHIOUREA AS ANTIBREAST CANCER CANDIDATES
Authors: D. Kesuma  , Siswandono  , A. Kirtishanti
Published: June 2022

Current breast cancer therapy does not always work optimally, and cases of resistance have been reported. Therefore, it is imperative to develop new effective drugs with minimal side effects through predictions of the epidermal growth factor receptor (EGFR) signalling pathway inhibition. Among chemicals with the potential as anticancer candidates for breast cancer are phenylthiourea derivatives. In this study, two phenylthiourea derivatives were synthesized: N- (4-methoxy)-benzoyl-N'-phenylthiourea and N-(4-trifluoromethyl)-benzoyl-N'-phenylthiourea. These compounds were docked with the EGFR receptor (code: 1M17.pdb) to predict their cytotoxic activity in silico using AutoDock tools. Furthermore, the microculture tetrazolium technique (MTT) was used to investigate in vitro cytotoxicity against MCF-7 cells. The in silico test revealed that the compounds N-(4-trifluoromethyl)-benzoyl-N'-phenylthiourea and N- (4-methoxy)-benzoyl-N'-phenylthiourea had a binding score of -8.2 and -7.3 kcal/mol, respectively, and the in vitro cytotoxic activity testing showed IC50 values of 0.37 mM and 0.38 mM, demonstrating significant EGFR inhibitory activity in MCF-7 cells. Therefore, it can be concluded that N-(4-trifluoromethyl)-benzoyl-N'-phenylthiourea has better cytotoxic activity than N-(4-methoxy)-benzoyl-N'-phenylthiourea.
INVESTIGATION OF THE CONVERSION PROCESS OF CALCIUM CHLORIDE OF SODA PRODUCTION DISTILLER LIQUID IN THE PRESENCE OF MIRABILITE AND THENARDITE
Authors: Anarbayev A.A. , Ormanova G.M. , Kabylbekova B.N. , Kucharov B. Kh. , Kenzhekhanova M. B.
Published: June 2022

The production of soda in the world is accompanied by a large amount of hard-to-recycle liquid waste (distiller liquid) in the form of a solution of CaCl2 and NaCl salts. To solve the problems of the soda industry, some countries of the world approach in different ways, liquid waste is drained into the seas and rivers. In some cases, distiller liquid is partially processed into calcium chloride or liquid road mixtures, building materials, etc. However, the disposal of liquid and solid waste from the soda industry does not always solve environmental problems in this region. In this regard, studies of the conversion of calcium chloride of distiller liquid using sodium sulphate of a mirabilite:thenardite mixture in various ratios have been carried out. It was found that the excess sodium sulphate and its stoichiometry lead to the jointprecipitation of calcium and sodium sulphates. In the process of conversion of calcium chloride with sodium sulphate in the ratio of natural mirabilite:thenardite = 100:0 occurs intensively due to the rapid dissolution of Na2SO4·10H2O. Conversion of calcium chloride at a norm of 0.92-1.0 and a temperature of 50-60°C at various ratios of mirabilite:thenardite shows that in the process of conversion of calcium chloride, the degree of conversion is reached to a maximum of 97% and at an optimum temperature of 50 °C, the stoichiometric norm of sodium sulphate 1.0 and the duration of 60 minutes. A further increase in temperature does not affect the degree of conversion of calcium chloride
Peningkatkan Motivasi Dan Wawasan Siswa Melalui Fieldtrip Observation
Authors: Hulu Fasaaro , Dewi Tisrin Maulina , Surahman Fadli , Sanusi Rahmat , Khairiyah Karunia Yulinda , Ristiani Ristiani
Published: June 2022

Pembelajaran learning from home (LFH) pada masa pandemic covid 19, siswa mendapat penurunan motivasi belajar; siswa tidak bisa keluar rumah dan tidak dapat berinteraksi secara langsung dengan guru atau teman saat belajar. Pendampingan peserta didik ini bertujuan untuk meningkatkan motivasi dan wawasan belajar siswa, melalui learning outdoor activities di tempat wisata Eco-edupark reserve Panbil Batam. Learning outdoor activities ini diikuti oleh 87 siswa. Siswa dibagi dalam 5 kelompok yang terdiri dari kelas kecil dan kelas besar dan setiap kelompok didampingi oleh tenaga pendidik. learning outdoor activities ini dapat meningkatkan motivasi, rasa ingin tahu yang tinggi dan membangun bakat siswa. Mendapat pengetahuan yang baru, mengamati hewan, membuat catan lapangan dan dapat mempresentasikan kegiatan yang telah dilakukan. Siswa memperoleh wawasan baru,  bersosial, kerjasama dan peduli lingkungan. Hasil dari pendapingan ini, wawasan, motivasi belajar dan kreatifitas siswa meningkat ditunjukkan pada hasil awal pengetahuan siswa, 60% dan akhir, 90%
Inovasi lengkuas Sebagai Produk Makanan Ringan dan Tambahan Pendapatan di Desa Sukamulya
Authors: Moh. Wahyu Aminullah  , Muhni Pamuji  , Dina Fitria
Published: June 2022

This community service is carried out with the aim of optimizing the use of galangal and community empowerment in Sukamulya Village in increasing income in a sustainable manner. The method used in this activity is by direct counseling and training to the community and making galangal innovations into galangal chips. The results obtained are that the large potential of galangal must be balanced with optimal utilization by processing it first rather than selling it directly to agents. This is also supported by the enthusiasm of the community in improving welfare. The need for collaboration in terms of marketing and sales from various parties, both local governments, communities, campus parties, and other stakeholders in order to improve the community's economy, and promote healthy snacks in the midst of this COVID-19 pandemic situation. This service can indirectly increase people's knowledge in managing the potential of galangal; cultivate the mindset of collaborating to form a community that has the potential to increase people's economic income; and efforts to produce galangal chips as souvenirs from Sukamulya village.
Workshop PTK dan Penulisan Proposal bagi Guru Madrasah Aliyah (MA) Badrul Islam Gulung ulung
Authors: Dedi Aprianto  , Muhammad Arfa  , Sasih Gunalan  , Hariono  , Bayu Aji Pamungkas
Published: June 2022

Doing a community service on workshop on the perspectives of Classroom Action Research (CAR) along with writing its proposal towards Islamic Senoir High School’s  teachers is based on urgent necessity letting them develop their knowledge on CAR as well as their writing skills of CAR’s proposal. It is worthy that workshop program is considered as an effective imput for the teachers to do CAR as one the parts of those’s instructional responsibility in purpose of improving learning-teaching activities in his/her classroom. CAR must have been as an important problem-solver to make the classroom’s problem up by doing it that it would have yielded the potential methods to undertake an effective classroom’s activities. The methods used used is based on the solution offered, giving the perspectives on CAR along with traning the teachers to write its proposal. This community program suggests that workshop on Classroom Action research was favorably conducted. It was assessed through questionnaires to require the teachers’ perception on workshop activities, namely their perception on knowledge and understanding on the perspectives of CAR 2.9. Furthermore the teachers’ competency on proposal writing activities were assessed 2.8. the assessment was adapted on Likert’s scale (1-4).
Prospects for Russian-Mongolian cooperation in the eyes of the citizens of the two countries
Authors: Litvinova Tatiana N. , Tsetsenbileg Tseveeniy , Zhelezniakov Aleksandr S.
Published: June 2022

The paper analyzes the results of sociological research conducted in Russia and Mongolia in order to identify the views of citizens of the two countries on the Russian-Mongolian relations and the prospects for the Greater Eurasian Partnership. In Mongolia, a field survey was conducted in 6 aimags (n=692); in Russia, an Internet survey was conducted (n=624), which was supplemented by expert views (n=27). The results showed high indices of mutual positive perception of Russians and Mongols (⁓81) among the countries of Eurasia. The study revealed a high level of interest and awareness of Mongols about Russia. Highlighting the priorities of economic development, the respondents named them based on the specialization of their country: for Russia – industry, science, tourism, energy; for Mongolia – animal husbandry, industry, tourism, education. It shows the objective need for rapprochement and establishment of trade, transport and energy cooperation on the basis of the international division of labor. It is the pragmatic and friendly relations as a result of long-term ties that serve as the basis for intercivilizational interaction between Russia and Mongolia in the context of integration processes in Eurasia.
Professions: Socio-Technological Dimension (Experience Of Methodological Analysis)
Authors: Toschenko Zhan T.
Published: June 2022

The article proposes to implement a special theoretical and methodological analysis, which is still little used in empirical research on various forms and types of professional activity. This analysis does not coincide with the officially existing classification, which includes and characterizes 450 professions (or 9 enlarged professional groups). The proposed approach is based on the classification of professions on the basis of their socio-technological measurement, which involves the use of such indicators as the subject of labor, the content and nature of labor, the conditions, means and methods for its implementation, taking into account the influence of the external environment and assessing the achieved indicators. Based on this approach, the article characterizes four groups of professions: man-technology, man-nature. man-man, man-creativity. This approach allows one to more deeply describe and understand the meaning of the profession, to reveal its essence and quality, to enrich ideas about the potential of each profession. And what is especially important - such an approach will make it possible to more clearly and substantively decide for each of these groups of professions, based on their general and special characteristics - how to really participate in solving such an important socio-economic task of the ongoing technological revolution - the growth of labor productivity, the rationalization of employment, increase in production efficiency.
Patrimonialism In Official Relations Of Russian Officials: On The Materials Of Pre-Revolutionary Empirical Studies
Authors: Chevtaeva Natalya
Published: June 2022

The reactualization of the little-known empirical research experience of ordinary provincial bureaucracy in pre-revolutionary Russia is presented. conducted by the magazine "Sputnik official" from 1911 to 1914. The analysis of questionnaires sharpens the problem: the evaluation of the official's work does not depend on the expectations of the population, but is entirely determined by the benevolence of the boss. It is necessary to cancel the infamous "third point" of the Civil Service Charter, when at the sole discretion of the chief, any objectionable official can be dismissed. Overcoming official disenfranchisement, involving independent commissions in solving personnel issues, developing social control on the part of society, providing the population with a greater share of self-government to understand the complexity of public administration – this is the way to establish trust between society and an official. The inclusion in the scientific arsenal of the experience of the formation of the sociology of officialdom in Russia demonstrates the heuristic value of studying the life world of this professional group; it allows us to understand which organizational and personal factors can become a brake, which are the driver of good governance, proper public administration in the interests of society.
About University Autonomy in Institutional Execution
Authors: Klucharev Grigoriy A.
Published: June 2022

The principle of university autonomy and academic freedom laid down by Wilhelm von Humboldt, one of the founders of modern higher education in Europe, does not just take root in Russian higher education. The state (federal) administration, which we called “institutional execution”, determines the main forms of university activity. Nevertheless, the entry into the Bologna process (USE, GIFO, educational loans, etc.), the successful implementation of the 5-100 and 2030 megaprojects allow us to talk about the sustainable development of higher professional education. The issue of access to quality education and overcoming inequalities is discussed.
Gender Differences in Grade 12 Mathematics Performance: Gauteng Province, South Africa
Authors: Letsoalo ME
Published: June 2022

Abstract This methodological, comparative and quantitative study aimed to compare the mathematics performance of male and female mathematics learners in Gauteng Province. The Umalusi council supplied the dataset used in this study, and it contained (18484 [46.63%] males, 21558 [53.84%] females and 1 [0.00%] undisclosed). The result from Pearson’s chi-square test indicated that male and female learners who enrolled for mathematics had comparable chances of passing Grade 12 (p = 0.061). Unadjusted (β = −2.667, p < 0.001, 95% CI : −3.120 to −2.215) and adjusted (β = −2.649, p < 0.001, 95% CI : −3.099 to −2.198) regression models indicated that males performed significantly better than their female counterparts in mathematics. This study recommended that a mathematics learning intervention be used at an early stage in a learner’s educational career. There is a need to conduct similar studies (using the latest data available) in all other South Africa’s provinces to validate the results presented by this study.
Seasonal Variation of GPS Accuracy and Precision in Forest Road Mapping
Authors: Abdi E. , Soofi Mariv H. , Mashayekhi Z. , Deljouei A. , Rahbarisisakht S.
Published: June 2022

GPS receivers are frequently used for engineering activities in forests; however, a number of factors, including natural barriers (mountain and tree canopy) in the forested areas, affect their accuracy. The aim of this study was to evaluate the accuracy and precision of a consumer-grade GPS (Colorado 300) receiver in road mapping. For this purpose, a length of 12.2 km of main forest road was selected in the Hyrcanian forest, northern Iran, and a ground truth map was extracted from the National Cartographic Center maps. The forest road was mapped in four seasons for three days to evaluate the seasons’ effects on the location accuracy and five- and ten-meter buffers were used for the same purpose. The results of two-way ANOVA showed that there were significant differences in the precision and accuracy of the GPS receiver due to the season. The best and worst mean accuracy and precision were in spring (24.45 m and 24.97 m) and autumn (56.10 m and 53.65 m), respectively. The findings showed a positive effect of averaging (5-61% improvement in relation to season) on the position accuracy. Also, ANOVA did not show any significant differences between the overlay lengths due to season in both the five-and ten-meter buffers. It can be concluded that consumer-grade GPS receivers could meet forestry needs. The averaged accuracies in spring are acceptable for many forestry applications and satisfy the mapping requirements.
A Review on the Mechanization of Date Palm Cultivation
Authors: Nourani A. , Garbati Pegna F.
Published: June 2022

Date palm is important cultivation for arid regions and its cultivation is expanding, though challenges to its modernization still remain partially unsolved: the mechanization of the most important farming operations is not fully developed, though various attempts have been carried out over time. The aim of this review paper is to provide an overview of the most characterizing research works directed at mechanizing farm operations for date palms in the three main morphological zones: crown, trunk, and roots. Various parameters such as maneuverability, working height, payload, cost, and working capacity have been considered by different authors for the performance analysis of their proposals, though safety is considered by all the main drivers of the research. The projects that have been developed and the relevant results can provide a useful reference for those who want to engage in further developing this sector or in applying some of the more effective proposed solutions. In order to promote this field of research, these attempts of mechanization of date palm cultivation need to concretize it with commercialised devices and machines mainly by strengthening the channels of technology transfer between the university and the socio-economic world on the one hand, and by encouraging the industry to adopt these research results, on the other.
STANDARDISASI PARAMETER NON SPESIFIK DAN SPESIFIK EKSTRAK ETANOL DAUN JAMBLANG (Syzygium cumini (L.) Skeels)
Authors: Ulfah Maria , Kurniawan Ricky Chandra , Erny Metalia
Published: June 2022

ABSTRACT

The content of active compounds and the quality of extracts cannot be guaranteed to always be in a

constant amount, so it is necessary to standardize. This study aims to prove the ethanol extract of

jamblang leaves (Syzygium cumini (l.) Skeels) fulfill the standardization of non-specific and specific

parameters as a natural medicine. The ethanol extract of jamblang leaves was extracted by extracting

using ultrasonic methods The extract was tested for non-specific parameters including: determination

of water content, total ash content, acid insoluble ash content, drying losses and heavy metal

contamination. Whereas the specific parameter tests include: identity, organoleptic extract,

compounds dissolved in water and ethanol, and chemical content. Test results were analyzed

descriptively and compared to standard parameters. The results of non-specific parameters showed a

moisture content of 8.04 ± 2.83%, a total ash content of 3.81 ± 1.95%, an acid insoluble ash content of

0.54 ± 0.73%, a drying loss of 9.08 ± 3.01, metal contamination Pb
FORMULASI SPRAY GEL EKSTRAK ETANOL BIJI KEDELAI (Glycine max) SEBAGAI SEDIAAN KOSMETIK TABIR SURYA
Authors: Akbar M_Rifki Pratama_Kharisma , Hanik Faza Putri_Maulina , Shabrina Ayu , Zulfa Elya
Published: June 2022

ABSTRACT

Skin damage caused by free radicals disturbs the health of human skin that needs protection.

Soybean extract showed that its SPF value was 6,93 on concentration of 0,5%. The purpose of this

study was to determine the effect of variation concentrations of Soybean Seed Ethanol Extract

(SSEE) on spray gel characteristic and sunscreen activity in vitro. Soybean seeds were extracted by

maceration method using 96% ethanol solvent. Extracts obtained were made into spray gel

preparation with variations of SSEE concentration were 2% (F1), 4% (F2), 6% (F3). SSEE spray

gel was tested for organoleptic, homogeneity, pH, viscosity, spraying pattern and sunscreen

activity test. Data from organoleptic, homogeneity, viscosity, pH and spray patterns and sunscreen

activity were analyzed descriptively while viscosity was analyzed using linear regression. The

spray gels were homogenous with thick texture, and brownish yellow color also distinctive aroma

of soybean seeds. Based on the test results, variations concentrations of SSEE did not affect the

spray gel characteristics except the viscosity that decreased. Sunscreen activity test showed that

SPF values were 13.82 (F1), 13.96 (F2) and 14.54 (F3) included maximal protection.

Keywords: soybeans, sunscreen, spray gel, in vitro
PENGANTAR REDAKSI
Authors: Redaksi Pengantar
Published: June 2022

Assalamualaikum Wr.WbAlhamdulillah seiring dengan perjalanan Fakultas Farmasi Universitas Wahid Hasyim Semarang, Jurnal Ilmu Farmasi dan Farmasi Klinik (JIFFK) telah memasuki tahun ke-17 semenjak penerbitan perdana tahun 2004. Kami tetap berharap bahwa JIFFK dapat memberikan kontribusi bagi perkembangan ilmu farmasi dan farmasi klinik. Kami berharap bahwa JIFFK ini dapat digunakan sebagai wadah bagi para peneliti, akademisi dan pemerhati ilmu farmasi dan farmasi klinik untuk mempublikasikan hasil penelitian atau pemikirannya. Demi menjaga eksistensi dan sustainabilitas JIFFK kami senantiasa memohon sumbangan tulisan atau artikel dari para peneliti. Kami selalu berusaha untuk dapat meningkatkan kualitas dari setiap penerbitan JIFFK ini, karena kami memiliki cita-cita supaya JIFFK dapat terakreditasi dari dikti. Akhir kata kami sampaikan terima kasih yang sebesar-besarnya kepada semua pihak yang telah membantu terlaksananya penerbitan ini. Kritik dan saran kami nantikan dari pembaca sekalian demi perbaikan dan kemajuan JIFFK.Wassalamu’alaikum Wr. Wb
PERBEDAAN KADAR FLAVONOID TOTAL EKSTRAK DAUN SALAM (Syzygium polyanthum) DENGAN METODE REFLUKS DARI BEBERAPA JENIS PELARUT DAN AKTIVITAS ANTIBAKTERI
Authors: Hastuti Yuliana Dewi , Kunti Mulangsri Dewi Andini
Published: June 2022

ABSTRACTBay leaves that it contains flavonoid compounds can inhibit the growth of Escherichia coli bacteria causes diarrhea. Hot extraction method can extract more compounds in the plants, particularly are heat stable. This study aimed to determine the different of total flavonoid content and antibacterial activity against Escherichia coli from bay leaves extracts that extracted with some solvent by reflux. The bay leaves extract was extracted with 70% ethanol, 96% ethanol, and methanol solvent. The spectrophotometric method was used to determine of total flavonoid contents at λmax 431,5 nm and operating time 30 minutes with AlCl₃ reagent. The disc diffusion method was used antibacterial activity test with chloramphenicol as a positive control and dimethyl sulfoxide as negative control. Analysis data of total flavonoid content with One Way Anova statistics, meanwhile the zone of inhibition from antibacterial activity test analysed by Two Way Anova continued with Tukey. The total flavonoid content of bay leaves extract (ethanol 70%, ethanol 96%, and methanol) were 6,089; 5,028; 4,052 mgQE/gram extract. There was significant difference of total flavonoid content between variation solvent and the most highest at 70% ethanol. Different extraction solvent and concentration serial of bay leaves extract showed significant difference and the most highest zone of inhibition at extract with 96% ethanol solvent.Keywords: antibacterial activity, bay leaf (Syzygium polyanthum), total flavonoid content, reflux
PENGARUH JENIS MINYAK NABATI TERHADAP KARAKTERISTIK FISIK SEDIAAN BALSAM STICK EKSTRAK ETANOL DAUN KERSEN (Muntingia calabura L.)
Authors: Nugrahaeni Fitria , Widayanti Ari , Primatama Gede Andika
Published: June 2022

ABSTRACTCherry leaves extract contain flavonoids which function as anti-inflammatory can be formed into stick balm preparations. The Stick balm is a preparation in the form of a stick consisting of a mixture of oil, wax and fat with a composition such that it can produce hardness and melting pont of as needed. The different properties of fatty acids in each type of oil can affect the physical properties of the balsam stick preparation in the form of melting point and hardness. This study aimed to determine the effect of adding olive oil, virgin coconut oil, castor oil, jojoba oil on the physical properties of the stick balm of Muntingia calabura L leaf extract. Physical characteristic of stick balm includes organolepti, homogeneity, melting point, hardness, and pH test. The results showed that all formulas met the physical characteristics of stick balms but each formula had differences in melting point, hardness, adhesion, and pH. The formula with the addition of olive oil showed the highest melting points and hardness at 55.3ºC and 8.16 mm. The results of statistical data was sig <0.05. This means that there are differences in melting point and hardness in each equation. Based on obeservations, it was concluded that the addition of vegetable oil to the balsam stick formulation affected the melting point and hardness.Keywords: hardness, melting point, Muntingia calabura L, olive oil, stick balm
The Development of Local History Learning Model Based on Progressivism to Promote Historical Thinking Skills
Authors: Fikri Asyrul , Mahdum Mahdum , Isjoni Isjoni
Published: June 2022

The issue is that history is generally taught in schools in a conventional manner, relying solely on textbook explanations and attempting to gather facts about what happened in the past. As a result, history classes have always come to be associated with memorization and recollection of past events, making it harder for students to acquire higher-order thinking abilities like historical thinking. To distribute the potential that students must possess, relevant paradigms, methods, tactics, models, and processes must be used to develop historical thinking abilities. The goal of this research is to develop a local history learning model based on the progressivism paradigm that will aid students in improving their historical thinking abilities. This study is a development studies project based on Thiagarajan, Semmel, and Semmel's 4D development design. The research stage is modified according to the needs and goals of the study. Interviews, open questionnaires, validation sheets, and historical thinking skills tests were used to gather data for the study. This study enlisted the participation of 160 students from Riau University's history education program. Our study's findings show that the local history learning model based on the progressive paradigm was valid and reliable as a learning model in local history learning and had a significant impact on students at Riau University's think historically. The summative evaluation indicated that the progressivism-based local history learning model was extremely effective in improving higher-order thinking abilities like historical thinking. Therefore, educators, including lecturers and teachers, may utilize this progressive
Development of WELIA (Website Linguistic Intelligence Assessment) for Class II Students of Elementary School
Authors: Kurniaman Otang , Noviana Eddy , Kurniawan Kurniawan , Mulyani Eva Astuti , Permana Dede , Sari Intan Kartika
Published: June 2022

The development of technology in the world of education is able to change technology-based education, thus the purpose of this research is to develop WELIA as an application that is able to measure the linguistic intelligence of students in elementary schools. The novelty in the research is designing WELIA (Website Linguistic Intelligence Assessment) which is used to assess or measure the linguistic intelligence of elementary school students using technology. The results showed that the average score of 3 practitioner validators on 11 components showed a figure of 81.81% - 93.18% with a very decent category level. The first practitioner validator gave an assessment with a very feasible category of 11 assessment components, so that a percentage value of 81.81% was obtained for media assessment. Expert validators on 11 components showed a score of 84.09% - 88.63% with a very feasible category level. The first expert validator gave an assessment with a very feasible category of 11 assessment components, so that a percentage value of 84.09% was obtained, it can be concluded that WELIA can be used to assess the linguistic intelligence of elementary school students.
Pengembangan Sistem Penggerak Roda pada Mekanisme Kerja Alat Uji Suspensi Menggunakan Motor BLDC
Authors: Junior Sumadi Haliman Abrahan , Anugrah Putri Sri Sasmita , Ka'ka Simon , Mukhtar Mukhtar
Published: June 2022

On a four-wheeler it takes comfort in driving. Using functional suspension systems to maximize performance from vehicles. The specific function of suspension that consists of absorbing oscillation and surprise vibrations, supporting weights, maintaining geometric wheels, adding traction to the wheel, and carrying on the braking style. The BLDC motor is one of the types of synchronous motors where the magnetic field produced by the stator and the magnetic field produced by the rotor spins at the same frequency. In writing this final assignment was used by the BLDC motor in order to control the velocity of the propulsion system on a conveyor test device to move the belt conveyor. The motor BLDC is controlled by a high power brushledd controlled which has an average voltage of 48 [v], an average of 35 [a], and an average power of 1000 [w]. The power supply is supplied from a power supply capable of producing 50 [v] tension and a current of 30 [a]. The suspension test came with a 16x2 LCD to show a junction for the shock junction of the springs, and was equipped with logger data to store the junction when the current charge used a 1 - centimeter roadblock against the springs. The junction mostly comes in a suspension with a pressure of 1-3 [bar] which is 6.4 [mm]. Based on the research and discussions it may be concluded that suspension devices could move the wheels of vehicles with additional loads and fixed speed and could identify the junction with the body of vehicles using the logger data.
Superusers of Self-Paced Online Learning on OpenWHO
Authors: Utunen Heini , Mattar Lama , Piroux Corentin , Ndiaye Ngouille , Christen Paula , Attias Melissa
Published: June 2022

Introduction: OpenWHO provides open-access, online, free and real-time learning responses to health emergencies, which includes capacitating healthcare providers, first liners, medical students and even the general public. During the pandemic and to date, an additional 40 courses for COVID-19 response have led to a massive increase in the number of learners and a change in user’s trends. This paper presents initial findings on enrollment trends, use and completion rates of health emergency courses offered on OpenWHO. Methods: The enrolment data statistics were drawn from OpenWHO’s built-in reporting system, which tracks learners’ enrolments, completion rates, demographics and other key course-related data, This information was collected from the beginning of the OpenWHO launch in 2017 up until October 2021. Results: Average course completion rate on OpenWHO including all courses and languages was equal to 45.9%. Nearly half (46.4%) of all OpenWHO learners have enrolled in at least 2 courses and 71 000 superusers have completed at least 10 courses on the platform. Conclusion: WHO’s learning platform during the pandemic registered record high completion rates and repeat learners enrollment. This highlights the massive impact of the OpenWHO online learning platform for health emergencies and the tangible knowledge transfer and access to health literacy.
Determining the Set of Items to Include in Breast Operative Reports, Using Clustering Algorithms on Retrospective Data Extracted from Clinical DataWarehouse
Authors: Boukobza Adrien , Wack Maxime , Neuraz Antoine , Geromin Daniela , Badoual Cécile , Bats Anne-Sophie , Burgun Anita , Koual Meriem , Tsopra Rosy
Published: June 2022

Medical reports are key elements to guarantee the quality, and continuity of care but their quality remains an issue. Standardization and structuration of reports can increase their quality, but are usually based on expert opinions. Here, we hypothesize that a structured model of medical reports could be learnt using machine learning on retrospective medical reports extracted from clinical data warehouses (CDW). To investigate our hypothesis, we extracted breast cancer operative reports from our CDW. Each document was preprocessed and split into sentences. Clustering was performed using TFIDF, Paraphrase or Universal Sentence Encoder along with K-Means, DBSCAN, or Hierarchical clustering. The best couple was TFIDF/K-Means, providing a sentence coverage of 89 % on our dataset; and allowing to identify 7 main categories of items to include in breast cancer operative reports. These results are encouraging for a document preset creation task and should then be validated and implemented in real life.
PeterPandemic: A Serious Game for Pandemic Management
Authors: Karthan Maximilian , Kreuder Annika , Frick Ulrich , Pryss Rüdiger , Schobel Johannes
Published: June 2022

The COVID-19 situation shows that a deep understanding of how pandemics spread and how they can be managed is important in a multitude of domains. Various studies have shown that students benefit from game-based learning approaches. Therefore, we introduce the concept of a web-based serious game to teach students important aspects when dealing with pandemic situations.
Ethical, Legal and Social Implications in a Nursing Field Study in Bavaria
Authors: Waibel Ann-Kathrin , Seifert Nadine , Swoboda Walter
Published: June 2022

The Institute DigiHealth of the University of Applied Sciences Neu-Ulm is planning ELSI guidelines and legal policies on data protection and making ethics requests for the CARE REGIO project, founded by the Bavarian State Ministry for Health and Care. CARE REGIO’s joint project aims at reforming the care system with digital solutions.
Assessing Disparities in COVID-19 Testing Using National COVID Cohort Collaborative
Authors: Lyu Jinyan , Cui Wanting , Finkelstein Joseph
Published: June 2022

With NCATS National COVID Cohort Collaborative (N3C) dataset, we evaluated 14 billion medical records and identified more than 12 million patients tested for COVID-19 across the US. To assess potential disparities in COVID-19 testing, we chose ten US states and then compared each state’s population distribution characteristics with distribution of corresponding characteristics from N3C. Minority racial groups were more prevalent in the N3C dataset as compared to census data. The proportion of Hispanics and Latinos in N3C was slightly lower than in the state census. Patients over 65 years old had higher representation in the N3C dataset and patients under 18 were underrepresented. Proportion of females in the N3C was higher compared with the state data. All ten states in N3C showed a higher representation of urban population versus rural population compared to census data.
Applying Participatory Design Mixed-Methods Approaches to Refine Twitter-Based Social Support Interventions for African Americans and Hispanic Family Caregivers of Persons with Dementia
Authors: Yoon Sunmoo , Broadwell Peter , Alcantara Carmela , Davis Nicole , Sun Frederick F. , de Planell Saguer Maria D. , Nho Joo Young , Mittelman Mary
Published: June 2022

We applied mixed-methods to refine our first version of the Twitter message library (English 400, translated into Spanish 400) for African Americans and Hispanic family caregivers for a person with dementia. We conducted a series of expert panels to collect quantitative and qualitative data using surveys and in-depth interviews. Using mixed methods to ensure unbiased results, the panelists first independently scored them (1 message/5 panelist) on a scale of 1 to 4 (1: lowest, 4: highest), followed by in-depth interviews and group discussions. Survey results showed that the average score was 3.47, indicating good to excellent (SD 0.35, ranges from 1.8 to 4). Quantitative surveys and qualitative interviews showed different results in emotional support messages.
Need of Equity in Virtual Mental Health in Canada in the Times of COVID-19
Authors: Kundi Bushra , El Morr Christo
Published: June 2022

We have conducted a systematic review on the use of virtual care for mental health purposes in Canada during COVID-19. Our review shows that existing infrastructures in Canada need to be adapted for eMental Health services to be offered proactively to the population. Equity is key for successful implementation.
CAREPATH: Developing Digital Integrated Care Solutions for Multimorbid Patients with Dementia
Authors: Pournik Omid , Ahmad Bilal , Lim Choi Keung Sarah N. , Khan Omar , Despotou George , Consoli Angelo , Ayadi Jaouhar , Gilardi Luca , Laleci Erturkmen Gokce Banu , Yuksel Mustafa , Gencturk Mert , Gappa Henrike , Breidenbach Martin , Mohamad Yehya , Velasco Carlos A. , Cramaiuc Oana , Ciobanu Cristiana , Gómez Jiménez Elena , Avendaño Céspedes Almudena , Alcantud Córcoles Rubén , Cortés Zamora Elisa Belén , Abizanda Pedro , Steinhoff Antje , Schmidt-Barzynski Wolfgang , Robbins Timothy , Kyrou Ioannis , Randeva Harpal , Ferrazzini Lionello , Arvanitis Theodoros N.
Published: June 2022

CAREPATH project is focusing on providing an integrated solution for sustainable care for multimorbid elderly patients with dementia or mild cognitive impairment. The project has a digitally enhanced integrated patient-centered care approach clinical decision and associated intelligent tools with the aim to increase patients’ independence, quality of life and intrinsic capacity. In this paper, the conceptual aspects of the CAREPATH project, in terms of technical and clinical requirements and considerations, are presented.
Parameters of variability of indicators of physique and productivity of Holstein cows depending on the level of milk yield
Authors: Konte A. , Karlikova Galina
Published: June 2022

Abstract. The purpose of research - to explore the genetic variability parameters of features the physique and productivity of Holstein cows, depending on the level of their milk yield. Research methods. The SELEX database was used. Animals (1610 heads) were divided into 3 groups according to milk yield per 1 lactation: 1 – milk yield no more 7500 kg, 2 – 7501–9000 kg, group 3 9001 kg of milk and more. Correlograms are based on R scripts in R-Studio. Results. Cows of the 3rd group are taller (p ≤ 0,001), with a deeper body (p ≤ 0,001), a wide rear and a greater udder depth (p ≤ 0,001). In group 3, milk yield and protein are higher (p ≤ 0,01). Animals of group 2 are taller (p ≤ 0,001), with high hind lobes, longer teats (p ≤ 0,001), and deep udders (p ≤ 0,01). In group 2, r according to the ratio: height in the sacrum / depth of the udder (0,58). Animals of the 3rd group - height in the sacrum / milky type (0,77), strength / depth of the body (0,63), height, width of the buttocks / height of the posterior lobes (0,62…0,60). In group 1, r between signs: height of the rear lobes / position of the hindquarters and depth of the udder (0,72...0,79), length of the front lobes / height of the hind lobes, udder depth / central ligament (0,60). According to the milk protein h² in animals of groups 2 and 3 0,52...0,74. Animals of the 3rd group have a high h² in terms of height, body depth, heel and udder height, body strength and udder depth. In group 2, high h² in terms of the depth of the body, the position of the rear, the angle of the hind legs from the side, the location of the front nipples, the length of the nipples, and the strength of the physique. Scientific novelty. The use of digital technologies in the evaluation of animals makes it possible to more accurately establish the relationship between the characteristics of the productivity of dairy animals and the physique and contributes to an increase in milk yield, the qualitative composition of milk and the longevity of cows.
Peran Guru PAI Dalam Mengembangkan Sumber Belajar PAI di SMP Negeri 2 Rejang Lebong
Authors: Mutiara sendi Okni aisa , Karolina Asri
Published: June 2022

Learning assets become the fundamental wellspring of learning in the execution of educator learning plays a significant part in the achievement of learning. The reason for this study needs to discover how the job of PAI instructors in creating PAI learning assets in SMP Negeri 2 Rejang Lebong. The strategies utilized subjectively by information assortment through talk with methods, perceptions and documentation and broke down utilizing miles et al approach are information decrease, information show and end withdrawal. This examination inferred that the job of PAI educators in creating PAI learning assets in SMP N 2 Rejang Lebong is by overseeing classes planning learning as per the metari to be instructed. Different learning assets will be utilized in the learning system adjusted to the material to be conveyed. Learning assets like printed books, modules, lks, pictures, then, at that point, it can likewise be with ecological items in schools, trees, or other plants.the utilization of instructor handbooks, lks, modules, existing books, mosques or mosques, then, at that point, school and educator conditions, online books or diaries, recordings, pictures, films that will give material. The learning media utilized in creating PAI learning assets in SMP Negeri 2 Rejang Lebong is the utilization of powert focuses, sound, pictures, banners, cardboard, radio, film, video.
TINJAUAN HUKUM TERHADAP KEABSAHAN PENYELESAIAN KLAIM PERJANJIAN ASURANSI MELALUI EX GRATIA DALAM PERSPEKTIF TEORI KEPASTIAN HUKUM
Authors: Faridy  , Mushafi
Published: June 2022

Artikel ini mengkaji tentang keabsahan penyelesaian klaim perjanjian asuransi melalui ex-gratia. Penyelesaian klaim perjanjian asuransi melalui nonlitigasi yaitu dengan cara negosiasi, mediasi melalui Badan Mediasi dan Arbitrase Asuransi Indonesia (BMAI), Ajudikasi dan Arbitrase. Akan tetapi belakangan mulai banyak perusahaan-perusahaan asuransi dalam menyelesaian klaim perjanjiannya menggunakan ex gratia. Dalam Undang-undang Nomor 40 Tahun 214 tentang Asuransi tidak ditemukan pasal yang menjelaskan ex gratia sebagai salah satu sarana penyelesaian klaim perjanjian asuransi. Begitu juga dalam Undang-Undang Nomor 30 Tahun 1999 tentang Arbitrase Dan Alternatif Penyelesaian Sengketa tidak ditemukan ketentuan yang jelas. Untuk itulah, melalui penelitian ini akan diungkap dan dianalisis keabsahan hukum penggunaan ex gratia sebagai wahana penyelesaian klaim perjanjian asuransi.

Kata Kunci: Keabsahan, Klaim Perjanjian Asuransi, Ex Gratia dan Kepastian Hukum
PENGATURAN TERHADAP PERSONAL GUARANTEE SEBAGAI JAMINAN PEMBERIAN KREDIT DI PT. BANK RIAU KEPRI CABANG TEMBILAHAN
Authors: Subhan
Published: June 2022

Penelitian ini bertujuan untuk menganalisis pengaturan dan prosedur pemberian fasilitas kredit dengan menggunakan jaminan Personal Guarantee sebagai jaminan dan upaya Bank Riau Kepri Cabang Tembilahan sebagai kreditur jika ada dibitur yang gagal memenuhi kewajibannya (wanprestasi). Jenis penelitian ini adalah yuridis empiris. Hasil penelitian dan pembahasan menemukan bahwa Pengaturan dan Prosedur Pemberian Fasilitas Kredit dilakukan dengan memperhatikan peraturan perundang-undangan yang berlaku khususnya yang berkaitan dengan Kitab Undang-Undang Hukum Perdata dan Undang-Undang Hak Tanggungan, dimana terkait dengan jaminan personal guarantee diterapkan kepada Debitur yang nilai pinjamannya melebihi wewenang pimpinan cabang Bank Riau Kepri Cabang Tembilahan. Jaminan Personal Guarante dilakukan dengan memperhatikan legalitas penjamin itu sendiri. Upaya yang dilakukan oleh PT. Bank Riau Kepri terhadap Kreditur yang gagal mememuhi kewajibannya dilakukan terlebih dahulu dengan upaya internal, yaitu penyelematan kredit dengan upaya Rekstrukturisasi Kredit, jika upaya internal gagal maka dilakukan dengan upaya eksternal dimana dengan melibatkan Pihak Kejaksaan Negeri Indragiri Hilir dengan dasar MoU antara Bank Riau Kepri Cabang Tembilahan dengan Kejaksaan Negeri Indragiri Hilir, dan jika upaya musyawarah dan mufakat dengan melibatkan pihak kejaksaan tetap gagal, maka selanjutnya Bank Riau Kepri menyerahkan penagihannya kepada Direktorat Jenderal Kekayaan Negara/Kantor Pelayanan Kekayaan Negara dan Lelang (DJKN/KPKNL). Kemudian KPKNL menerbitkan surat perintah penjualan barang sitaan. Surat tersebut diberitahukan secara tertulis kepada debitur atau penjamin sebagai upaya terakhir. Penjualan barang sitaan tersebut dapat dilakukan dengan cara melalui pelelangan, penjualan tidak melalui lelang atau penebusan.
Phenolic profile, antioxidant, DNA protection, acetylcholinesterase, butyrylcholinesterase and urease inhibition activities of Coriandrum sativum L. leaf, seed and flower extracts
Authors: OZEN Tevfik , YENIGUN Semiha , TOKA Mehmet
Published: June 2022

In this study, chemical content, antioxidant activities, enzyme inhibition activities, and DNA protection activities of extracts obtained from different solvents of the Coriandrum sativum leaf, flower and seed were determined. Total phenol and flavonoid contents of C. sativum leaf, seed and flower hexane extracts were higher than water, methanol, ethanol and ethyl acetate extracts. The highest anthocyanin content was found in the flower part of C. sativum. From the antioxidant activity tests, total antioxidant activity of flower aqueous extract, reducing power of seed aqueous extract, H2O2 scavenging activity of leaf ethyl acetate extract, OH˙ radical scavenging activity of leaf hexane extract, free radical scavenging activity of flower methanol extract, metal chelate activity of leaf ethyl acetate extract, superoxide anion scavenging activity of leaf aqueous extract and lipid peroxidation inhibition activity of the leaf ethyl acetate extract had the highest. It was found that the urease inhibition activity of the seed methanol extract and the acetylcholinesterase and butyrylcholinesterase inhibition activities of the seed ethanol extract presented effective inhibition activity as 80.30±0.20%, 112.83±10.75 µg/mL, and 334.28±23.09 µg/mL, respectively. The leaf hexane, flower ethyl acetate, and leaf methanol extracts showed the highest DNA protection activities with values of 71.86%, 70.89%, and 69.38%, respectively. According to the phytochemical content and biochemical activity results, this study is a valuable report proving that the C. sativum plant is a natural effective product.
La entrada de las bigtech en el negocio bancario: un análisis coste-beneficio
Authors: Padilla Jorge
Published: June 2022

La entrada de las bigtech puede transformar el negocio bancario de manera radical, en especial, los mercados de pagos y de crédito al consumo y a pymes. Aunque es de esperar que dicha entrada estimule la competencia en beneficio de los clientes de la banca minorista, también puede dar lugar a mercados crediticios aún más concentrados y aumentar la inestabilidad financiera. Que el resultado neto para la economía y, en particular, para los consumidores y las empresas sea positivo dependerá en buena medida de la actuación de reguladores y autoridades de competencia.
CURBING CHILD MARRIAGE AMONGST MUSLIMS IN MALAYSIA: TOWARDS LEGAL REFORM
Authors: Samuri Mohd Al Adib , Mohd Awal Noor Aziah , Abu Bakar Muhamad Abral
Published: June 2022

Child marriage is considered by the international community to be a violation of human rights, particularly the right to education and sexual and reproductive healthcare. Unfortunately, there are some Muslim countries in the world, including Malaysia, that has legalised this practice. Laws such as the Islamic family laws in all Malaysian states stipulate legal avenues for underage children to get married, provided they obtain permission from the Sharia court. Therefore, in order to end this harmful practice in Malaysian Muslim society, this article will discuss child marriage under Malaysian Islamic family law and propose a legal reform for Islamic family law regarding marriageable age and court procedure. This article examined international law instruments related to child marriage, Malaysian civil and Islamic laws, and reported cases to understand the legal complexities of child marriage in Malaysia. This article found that there is an urgent need for international agencies, Malaysian federal and state governments, religious authorities, and civil society movements to commence initiatives that address this issue to curb child marriage amongst Muslims in Malaysia, particularly through reforming Islamic family law in all states.
Peran Kepala dan Komite Sekolah Dalam Membangun Citra Positif Madrasah Diniyah
Authors: Pebriany Srie Amanah , Sanusi Nunung
Published: June 2022

Kesimpulan dari hasil penelitian ini menunjukan bahwa peran public relations dalam membangun citra MDTA Nurul Athfal menurut teori peran Dozier & Broom, yaitu 1) peran public relations sebagai penasehat ahli, peran ini dilakukan atas kerjasama komite sekolah serta kepala dalam memberi masukan dalam menyelesaikan konflik yang terjadi di sekolah, 2) peran public relations sebagai fasilitator komunikasi, peran ini dilakukan untuk menjembatani pihak internal dengan pihak eksternal sekolah MDTA Nurul Athfal ataupun sebaliknya, 3) peran public relations sebagai fasilitator proses pemecahan masalah, peran ini dijalankan komite sekolah dengan pelayanan sekolah kepada masyarakat yang direalisasikan dalam beberapa kegiatan, 4) peran public relations sebagai Teknisi komunikasi, dalam hal peran sebagai teknisi komunikasi ini diartikan oleh komite sekolah sebagai peng aplikasian dari semua program-program yang  sudah direncanakan.