bluuebunny/crossref_metadata_2025 huggingface dataset:
2D‐ and 3D‐Quantitative Structure‐Activity Relationship Studies for a Series of Phenazine N,N’‐Dioxide as Antitumour Agents
Authors: Cunha Jonathan Da , Lavaggi María Laura , Abasolo María Inés , Cerecetto Hugo , González Mercedes
Published: September 2011

Hypoxic regions of tumours are associated with increased resistance to radiation and chemotherapy. Nevertheless, hypoxia has been used as a tool for specific activation of some antitumour prodrugs, named bioreductive agents. Phenazine dioxides are an example of such bioreductive prodrugs. Our 2D‐quantitative structure activity relationship studies established that phenazine dioxides electronic and lipophilic descriptors are related to survival fraction in oxia or in hypoxia. Additionally, statistically significant models, derived by partial least squares, were obtained between survival fraction in oxia and comparative molecular field analysis standard model (r2 = 0.755, q2 = 0.505 and F = 26.70) or comparative molecular similarity indices analysis‐combined steric and electrostatic fields (r2 = 0.757, q2 = 0.527 and F = 14.93), and survival fraction in hypoxia and comparative molecular field analysis standard model (r2 = 0.736, q2 = 0.521 and F = 18.63) or comparative molecular similarity indices analysis‐hydrogen bond acceptor field (r2 = 0.858, q2 = 0.737 and F = 27.19). Categorical classification was used for the biological parameter selective cytotoxicity emerging also good models, derived by soft independent modelling of class analogy, with both comparative molecular field analysis standard model (96% of overall classification accuracy) and comparative molecular similarity indices analysis‐steric field (92% of overall classification accuracy). 2D‐ and 3D‐quantitative structure‐activity relationships models provided important insights into the chemical and structural basis involved in the molecular recognition process of these phenazines as bioreductive agents and should be useful for the design of new structurally related analogues with improved potency.
Affective Disorders
Authors: Beach Steven R. H. , Whisman Mark A.
Published: September 2011

Depression is a heterogeneous disorder with lifetime prevalence of “major depressive disorder” estimated to be 16.2%. Although the disorder is common and impairs functioning, it often goes untreated, with less than adequate response even when treated. We review research indicating the likely value of utilizing currently available, well‐validated, couple‐ and family‐based treatments with depressed individuals, and we provide empirically based treatment decision rules to guide effective application of marital and family interventions for depression in clinical practice. We suggest that traditional forms of couple‐based intervention may be most appropriate for discordant, depressed couples, whereas nondiscordant, or mildly distressed, depressed couples may respond well to forms of intervention that have become available more recently and which focus on strengthening the dyad as a source of support. We also discuss parent training as an intervention for depression and describe briefly the directions for future research to enhance couple‐based treatment for depression.
Catastrophic scapular fractures in Californian racehorses: Pathology, morphometry and bone density
Authors: VALLANCE S. A. , SPRIET M. , STOVER S. M.
Published: September 2011

Reasons for performing study:To enhance understanding of the nature and pathogenesis of scapular fractures in racehorses.

Hypothesis:Scapular fractures in racehorses have a consistent configuration related to sites of pre‐existing stress modelling and remodelling.

Methods:Fractured and intact scapulae collectedpost mortemwere examined visually and with computed tomography (CT). Scapular fracture configuration, bone modelling changes and standardised CT morphometry and density measurements were recorded. Statistical comparisons were made between fractured, nonfractured contralateral and control scapulae.

Results:Thirty‐nine scapulae from 10 Thoroughbred (TB) and 10 Quarter Horse (QH) racehorses were obtained. All 14 fractured scapulae (from 12 horses) had a consistent comminuted fracture configuration. A complete fracture coursed transversely through the neck of the scapula at the level of the distal aspect of the spine (8.9 ± 0.9 cm proximal to the lateral articular margin of the glenoid cavity). The distal fragment of 13 fractured scapulae was split into 2 major fragments by a fracture in the frontal plane that entered the glenoid cavity (2.8 ± 0.4 cm caudal to the cranial articular margin). Focal areas of periosteal proliferation and/or radiolucency were present in the distal aspect of the scapular spine of all fractured and intact contralateral scapulae, but less commonly (P<0.01) in intact scapula from horses without a scapular fracture. Fractured scapulae had 7–10% lower mean density and 46–104% greater density heterogeneity in the spine adjacent to the transverse fracture compared to control scapulae (P<0.03).

Conclusions and clinical relevance:Thoroughbred and QH racehorses have a characteristic scapular fracture configuration that is associated with pre‐existing pathology of the distal aspect of the spine. This location is consistent with scapular stress fractures diagnosed in lame TB racehorses. Catastrophic fracture is the acute manifestation of a more chronic process. Consequently, there are opportunities for early detection and prevention of fatalities.
Digital hypothermia inhibits early lamellar inflammatory signalling in the oligofructose laminitis model
Authors: VAN EPS A. W. , LEISE B. S. , WATTS M. , POLLITT C. C. , BELKNAP J. K.
Published: September 2011

Reasons for performing study: The pathophysiological events inhibited by prophylactic digital hypothermia that result in reduction of the severity of acute laminitis are unknown.

Objectives: To determine if digital hypothermia inhibits lamellar inflammatory signalling during development of oligofructose (OF) induced laminitis.

Methods: Fourteen Standardbred horses were given 10 g/kg bwt OF by nasogastric tube with one forelimb (CRYO) continuously cooled by immersion in ice and water and one forelimb (NON‐RX) at ambient temperature. Lamellae were harvested prior to the onset of lameness (24 h post OF administration, DEV group, n = 7) or at the onset of lameness (OG1 group, n = 7). Lamellar mRNA was purified and cDNA produced for real time‐quantitative PCR analysis of mRNA concentrations of cytokines (IL‐6, IL‐1β, IL‐10), chemokines (CXCL1, CXCL6, CXCL8/IL‐8, MCP‐1, MCP‐2), cell adhesion molecules (ICAM‐1, E‐selectin), COX‐2 and 3 housekeeping genes. Data were analysed (NON‐RX vs. CRYO, NON‐RX vs. archived control [CON, n = 7] lamellar tissue) using nonparametric tests.

Results: Compared with CON, the OG1 NON‐RX had increased (P<0.05) lamellar mRNA concentrations of all measured mediators except IL‐10, IL‐1β and MCP‐1/2, whereas only CXCL8 was increased (P<0.05) in DEV NON‐RX. Within the OG1 group, CRYO limbs (compared with NON‐RX) had decreased (P<0.05) mRNA concentrations of the majority of measured inflammatory mediators (no change in MCP‐1 and IL‐10). Within the DEV group, mRNA concentrations of CXCL‐1, ICAM‐1, IL‐1β, CXCL8 and MCP‐2 were decreased (P<0.05) and the anti‐inflammatory cytokine IL‐10 was increased (compared with NON‐RX limbs; P<0.05).

Conclusions: Digital hypothermia effectively blocked early lamellar inflammatory events likely to play an important role in lamellar injury including the expression of chemokines, proinflammatory cytokines, COX‐2 and endothelial adhesion molecules.

Potential relevance: This study demonstrates a potential mechanism by which hypothermia reduces the severity of acute laminitis, and may help identify molecular targets for future laminitis intervention.
Effects of acute exercise on angiotensin I‐converting enzyme (ACE) activity in horses
Authors: DE MELLO COSTA M. F. , ANDERSON G. A. , DAVIES H. M. , SLOCOMBE R. F.
Published: September 2011

Angiotensin I‐converting enzyme (ACE) level measurement in blood samples is an important tool in human medicine for the detection, treatment and control of diseases such as sarcoidosis and hypertension. Recently ACE has been advocated as being correlated to athletic aptitude in human athletes and a genetic polymorphism has been shown to be responsible for the enzymatic levels in the circulation. The objective of this research was to evaluate the effects of acute exercise in horses in order to increase the understanding of a possible correlation between ACE levels in plasma and performance in equine athletes. A standardised exercise test (SET) to fatigue was conducted on 8 horses and repeated venous blood collections carried out for ACE activity measurements before, during and after the SET. Our results show an increase in ACE activity up to fatigue and a return to baseline values at 30 min post exercise.
Cognitive correlates of performance in advanced mathematics
Authors: Wei Wei , Yuan Hongbo , Chen Chuansheng , Zhou Xinlin
Published: September 2011

Background. Much research has been devoted to understanding cognitive correlates of elementary mathematics performance, but little such research has been done for advanced mathematics (e.g., modern algebra, statistics, and mathematical logic).

Aims. To promote mathematical knowledge among college students, it is necessary to understand what factors (including cognitive factors) are important for acquiring advanced mathematics.

Samples. We recruited 80 undergraduates from four universities in Beijing.

Methods. The current study investigated the associations between students’ performance on a test of advanced mathematics and a battery of 17 cognitive tasks on basic numerical processing, complex numerical processing, spatial abilities, language abilities, and general cognitive processing.

Results. The results showed that spatial abilities were significantly correlated with performance in advanced mathematics after controlling for other factors. In addition, certain language abilities (i.e., comprehension of words and sentences) also made unique contributions. In contrast, basic numerical processing and computation were generally not correlated with performance in advanced mathematics.

Conclusions. Results suggest that spatial abilities and language comprehension, but not basic numerical processing, may play an important role in advanced mathematics. These results are discussed in terms of their theoretical significance and practical implications.
Cross‐ethnic friendships, perceived discrimination, and their effects on ethnic activism over time: A longitudinal investigation of three ethnic minority groups
Authors: Tropp Linda R. , Hawi Diala R. , Van Laar Colette , Levin Shana
Published: September 2011

This research examines cross‐ethnic friendships as a predictor of perceived discrimination and support for ethnic activism over time among African American, Latino American, and Asian American undergraduate participants from a multi‐year, longitudinal study conducted in the United States. Our research builds on prior cross‐sectional research by testing effects longitudinally and examining how relationships among these variables may differ across ethnic minority groups. Results indicate that, over time, greater friendships with Whites predict both lower perceptions of discrimination and less support for ethnic activism among African Americans and Latino Americans, but not among Asian Americans. Implications of these findings for future research on inter‐group contact, minority–majority relations, and ethnic group differences in status are discussed.
Resolving Lambertian surface orientation from fluctuating radiance
Authors: Makris Nicholas C. , Bertsatos Ioannis
Published: September 2011

A maximum likelihood method for estimating remote surface orientation from multi-static acoustic, optical, radar, or laser images is presented. It is assumed that the images are corrupted by signal-dependent noise, known as speckle, arising from complex Gaussian field fluctuations, and that the surface properties are effectively Lambertian. Surface orientation estimates for a single sample are shown to have biases and errors that vary dramatically depending on illumination direction. This is due to the signal-dependent nature of speckle noise and the nonlinear relationship between surface orientation, illumination direction, and fluctuating radiance. The minimum number of independent samples necessary for maximum likelihood estimates to become asymptotically unbiased and to attain the lower bound on resolution of classical estimation theory are derived, as are practical design thresholds.
Formant onsets and formant transitions as developmental cues to vowel perception
Authors: Ohde Ralph N. , German Sarah R.
Published: September 2011

The purpose of this study was to determine whether children give more perceptual weight than do adults to dynamic spectral cues versus static cues. Listeners were 10 children between the ages of 3;8 and 4;1 (mean 3;11) and ten adults between the ages of 23;10 and 32;0 (mean 25;11). Three experimental stimulus conditions were presented, with each containing stimuli of 30 ms duration. The first experimental condition consisted of unchanging formant onset frequencies ranging in value from frequencies for [i] to those for [a], appropriate for a bilabial stop consonant context. The second two experimental conditions consisted of either an [i] or [a] onset frequency with a 25 ms portion of a formant transition whose trajectory was toward one of a series of target frequencies ranging from those for [i] to those for [a]. Results indicated that the children attended differently than the adults on both the [a] and [i] formant onset frequency cue to identify the vowels. The adults gave more equal weight to the [i]-onset and [a]-onset dynamic cues as reflected in category boundaries than the children did. For the [i]-onset condition, children were not as confident compared to adults in vowel perception, as reflected in slope analyses.
Linear frequency modulation photoacoustic radar: Optimal bandwidth and signal-to-noise ratio for frequency-domain imaging of turbid media
Authors: Lashkari Bahman , Mandelis Andreas
Published: September 2011

The development of the pulse compression photoacoustic (PA) radar using linear frequency modulation (LFM) demonstrated experimentally that spectral matching of the signal to the ultrasonic transducer bandwidth does not necessarily produce the best PA signal-to-noise ratio, and it was shown that the optical and acoustic properties of the absorber will modify the optimal bandwidth. The effects of these factors are investigated in frequency-domain (FD) PA imaging by employing one-dimensional and axisymmetric models of the PA effect, and a Krimholtz–Leedom–Matthaei model for the employed transducers. LFM chirps with various bandwidths were utilized and transducer sensitivity was measured to ensure the accuracy of the model. The theory was compared with experimental results and it was shown that the PA effect can act as a low-pass filter in the signal generation. Furthermore, with the PA radar, the low-frequency behavior of two-dimensional wave generation can appear as a false peak in the cross correlation signal trace. These effects are important in optimizing controllable features of the FD-PA method to improve image quality.
Propagation of acoustic waves in a one-dimensional macroscopically inhomogeneous poroelastic material
Authors: Gautier G. , Kelders L. , Groby J. P. , Dazel O. , De Ryck L. , Leclaire P.
Published: September 2011

Wave propagation in macroscopically inhomogeneous porous materials has received much attention in recent years. The wave equation, derived from the alternative formulation of Biot’s theory of 1962, was reduced and solved recently in the case of rigid frame inhomogeneous porous materials. This paper focuses on the solution of the full wave equation in which the acoustic and the elastic properties of the poroelastic material vary in one-dimension. The reflection coefficient of a one-dimensional macroscopically inhomogeneous porous material on a rigid backing is obtained numerically using the state vector (or the so-called Stroh) formalism and Peano series. This coefficient can then be used to straightforwardly calculate the scattered field. To validate the method of resolution, results obtained by the present method are compared to those calculated by the classical transfer matrix method at both normal and oblique incidence and to experimental measurements at normal incidence for a known two-layers porous material, considered as a single inhomogeneous layer. Finally, discussion about the absorption coefficient for various inhomogeneity profiles gives further perspectives.
Medium characterization from interface-wave impedance and ellipticity using simultaneous displacement and pressure measurements
Authors: van Dalen K. N. , Drijkoningen G. G. , Smeulders D. M. J. , Heller H. K. J. , Glorieux C. , Sarens B. , Verstraeten B.
Published: September 2011

The interface-wave impedance and ellipticity are wave attributes that interrelate the full waveforms as observed in different components. For each of the fluid/elastic-solid interface waves, i.e., the pseudo-Rayleigh (pR) and Stoneley (St) waves, the impedance and ellipticity are found to have different functional dependencies on Young’s modulus and Poisson’s ratio. By combining the attributes in a cost function, unique and stable estimates of these parameters can be obtained, particularly when using the St wave. In a validation experiment, the impedance of the laser-excited pR wave is successfully extracted from simultaneous measurements of the normal particle displacement and the fluid pressure at a water/aluminum interface. The displacement is measured using a laser Doppler vibrometer (LDV) and the pressure with a needle hydrophone. Any LDV measurement is perturbed by refractive-index changes along the LDV beam once acoustic waves interfere with the beam. Using a model that accounts for these perturbations, an impedance decrease of 28% with respect to the plane wave impedance of the pR wave is predicted for the water/aluminum configuration. Although this deviation is different for the experimentally extracted impedance, there is excellent agreement between the observed and predicted pR waveforms in both the particle displacement and fluid pressure.
Effects of envelope shape on interaural envelope delay sensitivity in acoustic and electric hearing
Authors: Laback Bernhard , Zimmermann Inge , Majdak Piotr , Baumgartner Wolf-Dieter , Pok Stefan-Marcel
Published: September 2011

The envelope shape is important for the perception of interaural time difference (ITD) in the envelope as supported by the improved sensitivity for transposed tones compared to sinusoidally amplitude-modulated (SAM) tones. The present study investigated the effects of specific envelope parameters in nine normal-hearing (NH) and seven cochlear-implant (CI) listeners, using high-rate carriers with 27-Hz trapezoidal modulation. In NH listeners, increasing the off time (the silent interval in each modulation cycle) up to 12 ms, increasing the envelope slope from 6 to 8 dB/ms, and increasing the peak level improved ITD sensitivity. The combined effect of the off time and slope accounts for the gain in sensitivity for transposed tones relative to SAM tones. In CI listeners, increasing the off time up to 20 ms improved sensitivity, but increasing the slope showed no systematic effect. A 27-pulses/s electric pulse train, representing a special case of modulation with infinitely steep slopes and maximum possible off time, yielded considerably higher sensitivity compared to the best condition with trapezoidal modulation. Overall, the results of this study indicate that envelope-ITD sensitivity could be improved by using CI processing schemes that simultaneously increase the off time and the peak level of the signal envelope.
Verification of two minimally invasive methods for the estimation of the contact pressure in human vocal folds during phonation
Authors: Chen Li-Jen , Mongeau Luc
Published: September 2011

The contact pressure on the vocal fold surface during high pitch or amplitude voice production is believed to be one major source of phonotrauma. Models for the quantitative estimate of the contact pressure may be valuable for prevention and treatment. Various indirect and minimally invasive approaches have been purported to estimate contact pressure. But the accuracy of these methods has not yet been objectively verified in controlled laboratory settings. In the present study, two indirect approaches for the estimation of the contact pressure were investigated. One is based on a Hertzian impact model, and the other on a finite element model. A probe microphone was used for direct measurements of the contact pressure and verifications of the indirect approaches. A silicone replica of human vocal folds was used as a test bed. Consistent contact pressure estimations were obtained using all three methods. The advantages and disadvantages of each approach for eventual clinical applications are described.
In situ calibration of atmospheric-infrasound sensors including the effects of wind-noise-reduction pipe systems
Authors: Gabrielson Thomas B.
Published: September 2011

A worldwide network of more than 40 infrasound monitoring stations has been established as part of the effort to ensure compliance with the Comprehensive Nuclear Test Ban Treaty. Each station has four to eight individual infrasound elements in a kilometer-scale array for detection and bearing determination of acoustic events. The frequency range of interest covers a three-decade range—roughly from 0.01 to 10 Hz. A typical infrasound array element consists of a receiving transducer connected to a multiple-inlet pipe network to average spatially over the short-wavelength turbulence-associated “wind noise.” Although the frequency response of the transducer itself may be known, the wind-noise reduction system modifies that response. In order to understand the system’s impact on detection and identification of acoustical events, the overall frequency response must be determined. This paper describes a technique for measuring the absolute magnitude and phase of the frequency response of an infrasound element including the wind-noise-reduction piping by comparison calibration using ambient noise and a reference-microphone system. Measured coherence between the reference and the infrasound element and the consistency between the magnitude and the phase provide quality checks on the process.
A cocktail party model of spatial release from masking by both noise and speech interferers
Authors: Jones Gary L. , Litovsky Ruth Y.
Published: September 2011

A mathematical formula for estimating spatial release from masking (SRM) in a cocktail party environment would be useful as a simpler alternative to computationally intensive algorithms and may enhance understanding of underlying mechanisms. The experiment presented herein was designed to provide a strong test of a model that divides SRM into contributions of asymmetry and angular separation [Bronkhorst (2000). Acustica 86, 117–128] and to examine whether that model can be extended to include speech maskers. Across masker types the contribution to SRM of angular separation of maskers from the target was found to grow at a diminishing rate as angular separation increased within the frontal hemifield, contrary to predictions of the model. Speech maskers differed from noise maskers in the overall magnitude of SRM and in the contribution of angular separation (both greater for speech). These results were used to develop a modified model that achieved good fits to data for noise maskers (ρ = 0.93) and for speech maskers (ρ = 0.94) while using the same functions to describe separation and asymmetry components of SRM for both masker types. These findings suggest that this approach can be used to accurately model SRM for speech maskers in addition to primarily “energetic” noise maskers.
Sizing up the competition: Quantifying the influence of the mental lexicon on auditory and visual spoken word recognition
Authors: Strand Julia F. , Sommers Mitchell S.
Published: September 2011

Much research has explored how spoken word recognition is influenced by the architecture and dynamics of the mental lexicon (e.g., Luce and Pisoni, 1998; McClelland and Elman, 1986). A more recent question is whether the processes underlying word recognition are unique to the auditory domain, or whether visually perceived (lipread) speech may also be sensitive to the structure of the mental lexicon (Auer, 2002; Mattys, Bernstein, and Auer, 2002). The current research was designed to test the hypothesis that both aurally and visually perceived spoken words are isolated in the mental lexicon as a function of their modality-specific perceptual similarity to other words. Lexical competition (the extent to which perceptually similar words influence recognition of a stimulus word) was quantified using metrics that are well-established in the literature, as well as a statistical method for calculating perceptual confusability based on the phi-square statistic. Both auditory and visual spoken word recognition were influenced by modality-specific lexical competition as well as stimulus word frequency. These findings extend the scope of activation-competition models of spoken word recognition and reinforce the hypothesis (Auer, 2002; Mattys et al., 2002) that perceptual and cognitive properties underlying spoken word recognition are not specific to the auditory domain. In addition, the results support the use of the phi-square statistic as a better predictor of lexical competition than metrics currently used in models of spoken word recognition.
Modeling the eardrum as a string with distributed force
Authors: Goll Erich , Dalhoff Ernst
Published: September 2011

In this paper, an analytical model of the tympanic membrane is introduced where the two-dimensional tympanic membrane is reduced to a one-dimensional string. It is intended to bridge the gap between lumped-element models and finite-element models. In contrast to known lumped-element models, the model takes the distributed effect of the sound field on the tympanic membrane into account. Compared to finite-element models, it retains the advantage of a low number of parameters. The model is adjusted to forward and reverse transfer functions of the guinea-pig middle ear. Although the fitting to experimental data is not perfect, important conclusions can be drawn. For instance, the model shows that the delay of surface waves on the tympanic membrane can be different from the signal transmission delay of the tympanic membrane. In a similar vein, the standing wave ratio on the tympanic membrane and within the ear canal can considerably differ. Further, the model shows that even in a low-loss tympanic membrane the effective area, which commonly is associated with the transformer ratio in a lumped-element and some hybrid circuit models, not only is frequency-dependent, but also different for forward and reverse transduction.
Generalized response of a sphere embedded in a viscoelastic medium excited by an ultrasonic radiation force
Authors: Urban Matthew W. , Nenadic Ivan Z. , Mitchell Scott A. , Chen Shigao , Greenleaf James F.
Published: September 2011

The response of an embedded sphere in a viscoelastic medium excited by acoustic radiation force has been studied in both the time- and frequency-domains. This model is important because it can be used to characterize the viscoelastic properties of the medium by fitting the response to the theoretical model. The Kelvin–Voigt model has been used exclusively in these models. An extension to the previously reported models is described so that any viscoelastic rheological model can be used. This theoretical development describes the generalized embedded sphere response both in the time and frequency domains. Comparing the results from derivations in both domains showed very good agreement with a median absolute error (MAE) ranging from 0.0044 to 0.0072. Good agreement is demonstrated with finite element model simulations and the theory with a MAE of 0.006. Lastly, results for characterization of gelatin and rubber materials with the new theory are shown where the MAE values were used to determine which rheological model best describes the measured responses.
The impact of reverberant self-masking and overlap-masking effects on speech intelligibility by cochlear implant listeners (L)
Authors: Kokkinakis Kostas , Loizou Philipos C.
Published: September 2011

The purpose of this study is to determine the relative impact of reverberant self-masking and overlap-masking effects on speech intelligibility by cochlear implant listeners. Sentences were presented in two conditions wherein reverberant consonant segments were replaced with clean consonants, and in another condition wherein reverberant vowel segments were replaced with clean vowels. The underlying assumption is that self-masking effects would dominate in the first condition, whereas overlap-masking effects would dominate in the second condition. Results indicated that the degradation of speech intelligibility in reverberant conditions is caused primarily by self-masking effects that give rise to flattened formant transitions.
Effects of multiple scattering, attenuation and dispersion in waveguide sensing of fish
Authors: Andrews Mark , Gong Zheng , Ratilal Purnima
Published: September 2011

An ocean acoustic waveguide remote sensing system can instantaneously image and continuously monitor fish populations distributed over continental shelf-scale regions. Here it is shown theoretically that the areal population density of fish groups can be estimated from their incoherently averaged broadband matched filtered scattered intensities measured using a waveguide remote sensing system with less than 10% error. A numerical Monte-Carlo model is developed to determine the statistical moments of the scattered returns from a fish group. It uses the parabolic equation to simulate acoustic field propagation in a random range-dependent ocean waveguide. The effects of (1) multiple scattering, (2) attenuation due to scattering, and (3) modal dispersion on fish population density imaging are examined. The model is applied to investigate population density imaging of shoaling Atlantic herring during the 2006 Gulf of Maine Experiment. Multiple scattering, attenuation and dispersion are found to be negligible at the imaging frequencies employed and for the herring densities observed. Coherent multiple scattering effects, such as resonance shifts, which can be significant for small highly dense fish groups on the order of the acoustic wavelength, are found to be negligible for the much larger groups typically imaged with a waveguide remote sensing system.
Quasi-Gaussian beam analytical basis and comparison with an alternative approach (L)
Authors: Marston Philip L.
Published: September 2011

A superposition of propagating Bessel beams was recently numerically demonstrated to approximate a Gaussian beam and was used to evaluate the scattering by a sphere centered on the focal point of the beam. An analytical beam synthesis used in optics by Agrawal and Pattanayak [J. Opt. Soc. Am. 69, 575–578 (1979)] is found here to be recovered as the weak focusing limit of the quasi-Gaussian beam when evanescent contributions are omitted from the analytical synthesis. The propagating-wave part of the analytical synthesis has similarities to, and differences from, the recent quasi-Gaussian approximation.
Performances of human listeners and an automatic aural classifier in discriminating between sonar target echoes and clutter
Authors: Allen Nancy , Hines Paul C. , Young Victor W.
Published: September 2011

Human listening tests were conducted to investigate if participants could distinguish between samples of target echoes and clutter obtained from a broadband active sonar experiment. For each echo, the listeners assigned a rating based on how confident they were that it was a target echo or clutter. The measure of performance was the area under the binormal receiver-operating-characteristic (ROC) curve, Az. The mean performance was Az = 0.95 ± 0.04 when signals were presented with their full available acoustic bandwidth of approximately 0–2 kHz. It was Az = 0.77 ± 0.08 when the bandwidth was reduced to 0.5–2 kHz. The error bounds are stated as 95% confidence intervals. These results show that the listeners could definitely hear differences, but their performance was significantly degraded when the low-frequency signal information was removed. The performance of an automatic aural classifier was compared against this human-performance baseline. Results of statistical tests showed that it outperformed 2 of 13 listeners and 5 of 9 human listeners in the full-bandwidth and reduced-bandwidth tests, respectively, and performed similarly to the other listeners. Given its performance, the automatic aural classifier may prove beneficial to Navy sonar systems.
Nonlinear acoustic wave equations with fractional loss operators
Authors: Prieur Fabrice , Holm Sverre
Published: September 2011

Fractional derivatives are well suited to describe wave propagation in complex media. When introduced in classical wave equations, they allow a modeling of attenuation and dispersion that better describes sound propagation in biological tissues. Traditional constitutive equations from solid mechanics and heat conduction are modified using fractional derivatives. They are used to derive a nonlinear wave equation which describes attenuation and dispersion laws that match observations. This wave equation is a generalization of the Westervelt equation, and also leads to a fractional version of the Khokhlov–Zabolotskaya–Kuznetsov and Burgers’ equations.
Acoustic inversions for measuring boundary layer suspended sediment processes
Authors: Thorne Peter D. , Hurther David , Moate Benjamin D.
Published: September 2011

Although sound has been applied to the study of sediment transport processes for a number of years, it is acknowledged that there are still problems in using the backscattered signal to measure suspended sediment parameters. In particular, when the attenuation due to the suspension becomes significant, the uncertainty associated with the variability in the scattering characteristics of the sediments in suspension can lead to inversion errors which accumulate as the sound propagates through the suspension. To study this attenuation propagation problem, numerical simulations and laboratory experiments have been used to assess the impact unpredictability in the scattering properties of the suspension has on the acoustically derived suspended sediments parameters. The results clearly show the commonly applied iterative implicit inversion can lead to calculated sediment parameters, which become increasingly erroneous with range, as the sound propagates through the suspension. To address this problem an alternative approach to the iterative implicit formulation is investigated using a recently described dual frequency inversion. This approach is not subject to the accumulation of errors and has an explicit solution. Here the dual frequency inversion is assessed and calculated suspended sediment parameters are compared with those obtained from the iterative implicit inversion.
Sound, infrasound, and sonic boom absorption by atmospheric clouds
Authors: Baudoin Michaël , Coulouvrat François , Thomas Jean-Louis
Published: September 2011

This study quantifies the influence of atmospheric clouds on propagation of sound and infrasound, based on an existing model [Gubaidulin and Nigmatulin, Int. J. Multiphase Flow 26, 207–228 (2000)]. Clouds are considered as a dilute and polydisperse suspension of liquid water droplets within a mixture of dry air and water vapor, both considered as perfect gases. The model is limited to low and medium altitude clouds, with a small ice content. Four physical mechanisms are taken into account: viscoinertial effects, heat transfer, water phase changes (evaporation and condensation), and vapor diffusion. Physical properties of atmospheric clouds (altitude, thickness, water content and droplet size distribution) are collected, along with values of the thermodynamical coefficients. Different types of clouds have been selected. Quantitative evaluation shows that, for low audible and infrasound frequencies, absorption within clouds is several orders of magnitude larger than classical absorption. The importance of phase changes and vapor diffusion is outlined. Finally, numerical simulations for nonlinear propagation of sonic booms indicate that, for thick clouds, attenuation can lead to a very large decay of the boom at the ground level.
Reconstruction of the signal produced by a directional sound source from remote multi-microphone recordings
Authors: Guarato Francesco , Hallam John , Matsuo Ikuo
Published: September 2011

A mathematical method for reconstructing the signal produced by a directional sound source from knowledge of the same signal in the far field, i.e., microphone recordings, is developed. The key idea is to compute inverse filters that compensate for the directional filtering of the signal by the sound source directivity, using a least-square error optimization strategy. Previous work pointed out how the method strongly depends on arrival times of signal in the microphone recordings. Two strategies are used in this paper for calculating the time shifts that are afterward taken as inputs, together with source directivity, for the reconstruction. The method has been tested in a laboratory environment, where ground truth was available, with a Polaroid transducer as source. The reconstructions are similar with both strategies. The performance of the method also depends on source orientation.
Perception of intrusive /r/ in English by native, cross-language and cross-dialect listeners
Authors: Tuinman Annelie , Mitterer Holger , Cutler Anne
Published: September 2011

In sequences such as law and order, speakers of British English often insert /r/ between law and and. Acoustic analyses revealed such “intrusive” /r/ to be significantly shorter than canonical /r/. In a 2AFC experiment, native listeners heard British English sentences in which /r/ duration was manipulated across a word boundary [e.g., saw (r)ice], and orthographic and semantic factors were varied. These listeners responded categorically on the basis of acoustic evidence for /r/ alone, reporting ice after short /r/s, rice after long /r/s; orthographic and semantic factors had no effect. Dutch listeners proficient in English who heard the same materials relied less on durational cues than the native listeners, and were affected by both orthography and semantic bias. American English listeners produced intermediate responses to the same materials, being sensitive to duration (less so than native, more so than Dutch listeners), and to orthography (less so than the Dutch), but insensitive to the semantic manipulation. Listeners from language communities without common use of intrusive /r/ may thus interpret intrusive /r/ as canonical /r/, with a language difference increasing this propensity more than a dialect difference. Native listeners, however, efficiently distinguish intrusive from canonical /r/ by exploiting the relevant acoustic variation.
Transient nearfield acoustic holography based on an interpolated time-domain equivalent source method
Authors: Zhang Xiao-Zheng , Bi Chuan-Xing , Zhang Yong-Bin , Xu Liang
Published: September 2011

Transient nearfield acoustic holography based on an interpolated time-domain equivalent source method (ESM) is proposed to reconstruct transient acoustic fields directly in the time domain. Since the equivalent source strengths solved by the traditional time-domain ESM formulation cannot be used to reconstruct the pressure on the source surface directly, an interpolation function is introduced to develop an interpolated time-domain ESM formulation which permits one to deduce an iterative reconstruction process. As the reconstruction process is ill-conditioned and especially there exists a cumulative effect of errors, the Tikhonov regularization is used to stabilize the process. Numerical examples of reconstructing transient acoustic fields from a baffled planar piston, an impulsively accelerating sphere and a cube box, respectively, demonstrate that the proposed method not only can effectively reconstruct transient acoustic fields in the time domain, but also can visualize acoustic fields in the space domain. And, in the first numerical example, the cumulative effect of errors and the validity of using the Tikhonov regularization to suppress the errors are described.
Acoustic analysis and mood classification of pain-relieving music
Authors: Knox Don , Beveridge Scott , Mitchell Laura A. , MacDonald Raymond A. R.
Published: September 2011

Listening to preferred music (that which is chosen by the participant) has been shown to be effective in mitigating the effects of pain when compared to silence and a variety of distraction techniques. The wide range of genre, tempo, and structure in music chosen by participants in studies utilizing experimentally induced pain has led to the assertion that structure does not play a significant role, rather listening to preferred music renders the music “functionally equivalent” as regards its effect upon pain perception. This study addresses this assumption and performs detailed analysis of a selection of music chosen from three pain studies. Music analysis showed significant correlation between timbral and tonal aspects of music and measurements of pain tolerance and perceived pain intensity. Mood classification was performed using a hierarchical Gaussian Mixture Model, which indicated the majority of the chosen music expressed contentment. The results suggest that in addition to personal preference, associations with music and the listening context, emotion expressed by music, as defined by its acoustical content, is important to enhancing emotional engagement with music and therefore enhances the level of pain reduction and tolerance.
Dynamical energy analysis for built-up acoustic systems at high frequencies
Authors: Chappell D. J. , Giani S. , Tanner G.
Published: September 2011

Standard methods for describing the intensity distribution of mechanical and acoustic wave fields in the high frequency asymptotic limit are often based on flow transport equations. Common techniques are statistical energy analysis, employed mostly in the context of vibro-acoustics, and ray tracing, a popular tool in architectural acoustics. Dynamical energy analysis makes it possible to interpolate between standard statistical energy analysis and full ray tracing, containing both of these methods as limiting cases. In this work a version of dynamical energy analysis based on a Chebyshev basis expansion of the Perron-Frobenius operator governing the ray dynamics is introduced. It is shown that the technique can efficiently deal with multi-component systems overcoming typical geometrical limitations present in statistical energy analysis. Results are compared with state-of-the-art hp-adaptive discontinuous Galerkin finite element simulations.
Aeroacoustic sources of motorcycle helmet noise
Authors: Kennedy J. , Adetifa O. , Carley M. , Holt N. , Walker I.
Published: September 2011

The prevalence of noise in the riding of motorcycles has been a source of concern to both riders and researchers in recent times. Detailed flow field information will allow insight into the flow mechanisms responsible for the production of sound within motorcycle helmets. Flow field surveys of this nature are not found in the available literature which has tended to focus on sound pressure levels at ear as these are of interest for noise exposure legislation. A detailed flow survey of a commercial motorcycle helmet has been carried out in combination with surface pressure measurements and at ear acoustics. Three potential noise source regions are investigated, namely, the helmet wake, the surface boundary layer and the cavity under the helmet at the chin bar. Extensive information is provided on the structure of the helmet wake including its frequency content. While the wake and boundary layer flows showed negligible contributions to at-ear sound the cavity region around the chin bar was identified as a key noise source. The contribution of the cavity region was investigated as a function of flow speed and helmet angle both of which are shown to be key factors governing the sound produced by this region.
A hybrid approach for predicting the distribution of vibro-acoustic energy in complex built-up structures
Authors: Maksimov Dmitrii N , Tanner Gregor
Published: September 2011

Finding the distribution of vibro-acoustic energy in complex built-up structures in the mid-to-high frequency regime is a difficult task. In particular, structures with large variation of local wavelengths and/or characteristic scales pose a challenge referred to as the mid-frequency problem. Standard numerical methods such as the finite element method (FEM) scale with the local wavelength and quickly become too large even for modern computer architectures. High frequency techniques, such as statistical energy analysis (SEA), often miss important information such as dominant resonance behavior due to stiff or small scale parts of the structure. Hybrid methods circumvent this problem by coupling FEM/BEM and SEA models in a given built-up structure. In the approach adopted here, the whole system is split into a number of subsystems that are treated by either FEM or SEA depending on the local wavelength. Subsystems with relative long wavelengths are modeled using FEM. Making a diffuse field assumption for the wave fields in the short wave length components, the coupling between subsystems can be reduced to a weighted random field correlation function. The approach presented results in an SEA-like set of linear equations that can be solved for the mean energies in the short wavelength subsystems.
Detection and rate discrimination of amplitude modulation in electrical hearing
Authors: Chatterjee Monita , Oberzut Cherish
Published: September 2011

Three experiments were designed to examine temporal envelope processing by cochlear implant (CI) listeners. In experiment 1, the hypothesis that listeners’ modulation sensitivity would in part determine their ability to discriminate between temporal modulation rates was examined. Temporal modulation transfer functions (TMTFs) obtained in an amplitude modulation detection (AMD) task were compared to threshold functions obtained in an amplitude modulation rate discrimination (AMRD) task. Statistically significant nonlinear correlations were observed between the two measures. In experiment 2, results of loudness-balancing showed small increases in the loudness of modulated over unmodulated stimuli beyond a modulation depth of 16%. Results of experiment 3 indicated small but statistically significant effects of level-roving on the overall gain of the TMTF, but no impact of level-roving on the average shape of the TMTF across subjects. This suggested that level-roving simply increased the task difficulty for most listeners, but did not indicate increased use of intensity cues under more challenging conditions. Data obtained with one subject, however, suggested that the most sensitive listeners may derive some benefit from intensity cues in these tasks. Overall, results indicated that intensity cues did not play an important role in temporal envelope processing by the average CI listener.