bluuebunny/crossref_metadata_2025 huggingface dataset:
Mathematical modeling of pollution of underground aquifers due to mining of minerals
Authors: Pukish Arsen , Mandryk Oleh , Arkhypova Liudmyla , Syrovets Serhii , Hryniuk Diana
Published: September 2024

Purpose. The research aims to create a mathematical model of salt contamination spreading through underground aquifers in the event of depressurization of the hydrocarbon production well crater for further assessment of environmental and economic damage from these processes. Methods. To predict the environmental and economic damage from salt contamination, the distribution of concentrations of harmful substances was investigated, taking into account the number of supply sources and their intensity over time, based on situ studies at the Rybalske Oil Field, Okhtyrskyi District of Sumska Oblast in Ukraine, where there were technological failures wells, accompanied by open fountains with the release of large amounts of highly mineralized water and the formation of craters. Mathematical modelling methods were used to process the data from the study of accidental technogenic pollution of underground aquifers. Findings. Based on real data from the study of the processes of potential salt contamination spread in fresh aquifers as a result of accidents at hydrocarbon production facilities, a mathematical model of salt contamination spreading in drinking groundwater in the event of depressurization of an oil field well crater has been developed. Potential economic losses in case of possible groundwater contamination with highly mineralized solution, which can into drinking groundwater aquifers, are substantiated. It has been established that in connection with the occurrence of an emergency situation due to the release of formation water to the surface in the territory of oil and gas fields, the formation of technogenic meromictic reservoirs is possible, which is confirmed by the example of the Rybalske Oil Field. It is proved that the total mineralization of crater water increases linearly with depth of the reservoir occurrence, and a similar dependence is characteristic of the chloride ion content. Originality. For the first time, a multicomponent mathematical model of mineral salt migration processes in underground freshwater aquifers in the case of depressurization of a meromictic reservoir has been developed. Practical implications. The research results obtained using numerical methods make it possible to predict the processes of spreading harmful substances in drinking underground aquifers as a result of emergencies at oil and gas fields, taking into account the number of sources of pollutants penetrating the study area, the heterogeneity of properties of the environment into which the harmful substance enters, and to assess the dynamics of changes in the concentration of these substances and time with further assessment of environmental and economic damage from these processes.
Change in the qualitative composition of non-metallic mineral raw materials as a result of blasting operations
Authors: Saik Pavlo , Dreshpak Oleksandr , Ishkov Valerii , Cherniaiev Oleksii , Anisimov Oleh
Published: September 2024

Purpose. The research purpose is to study the change in the qualitative composition of granite before and after blasting operations to determine its compliance with the criteria of marketable products. Methods. X-ray phase and X-ray structural research methods are used to study changes in the mineral composition of granites before and after blasting operations. To separate magnetic and non-magnetic fractions of the selected granite samples, a three-roller RST magnetic separator is used. X-ray phase research is conducted using a DRON-3 diffractometer. Additionally, an analysis of the unit cell dimensions of the quartz crystal lattice was conducted, and the dislocation density along the corresponding crystallographic planes was studied. Findings. It has been determined that after blasting operations, granite mass is redistributed from coarse fractions of 1-20 mm to small fractions of 0-1 mm with an increase in the latter by 4.2%. It has been found that the biotite content decrea-ses naturally and consistently, and the quartz content increases correspondingly in products in the following series: magnetic separator drum (90%, 2%) → lower roller (72%, 14%) → upper roller (55%, 31%) → non-magnetic product (48%, 34%) before blasting operations. Therefore, despite significant differences in the magnetic favorability of these two mineral phases, they are present in all magnetic separation products (with the exception of quartz in the non-magnetic product): magnetic separator drum → lower roller → upper roller. Originality. It has been established that along the crystallographic directions 101 and 211, the maximum gradient of dislocation density increase in the quartz crystal lattice in granite samples before blasting operations is observed during the transition from the lower roller product to the upper roller product, amounting to 1.55·1010 and 6.63·1010 cm-2, respectively. After blasting operations, in granite samples along the same directions, the maximum gradient of dislocation density increase is observed between the upper roller product and the non-magnetic product, amounting to 3.01·1010 and 4.67·1010cm-2. As a result of the thermodynamic impact of blasting operations, the weighted average dislocation density value along crystallographic planes 101 and 211 in the quartz crystal lattice increases by 47.21 and 25.72%, respectively. Practical implications. Understanding the quality characteristics of marketable products after blasting operations will contribute to optimizing the stages of further processing of non-metallic mineral raw materials (two-, three- or four-stage crushing) and expanding the scope of granite applications. This increases its competitiveness in the building materials market by reducing the costs for additional processing with a reduction in the labor intensity of the process.
Research on purification of tailings solutions from metal impurities at lead dust processing enterprises
Authors: Altaibayev Bagdat , Tussupbayev Nessipbay , Kenzhetaev Zhiger , Baigenzhenov Omirserik , Khabiyev Alibek , Tyulyubayev Zekail , Leksin Alexey
Published: September 2024

Purpose. The research aims to develop a technology for tailings solution purification using membrane nanofiltration to reduce waste volume and enterprise costs by reusing the purified water. Methods. The research uses polyamide nanofiltration membranes on a semi-industrial plant. The nanofiltration process is conducted at a pressure of 3.5 MPa with 30% permeate yield. The chemical composition of the solutions is analyzed using atomic-absorption and chemical methods. Findings. Removal of 69% arsenic, 68.5% zinc and 95.7% iron has been achieved under optimal conditions. The purified solution with a residual sulphuric acid concentration of ~3.5 g/l can be used again for leaching lead dust. The concentrated metal solution allows for additional zinc extraction. The use of technology reduces waste volumes by more than 30% and reduces the enterprise’s recycling costs. Originality. The research proposes a new environmentally friendly nanofiltration technology for tailings solution purification that can effectively remove heavy metals and extract valuable components. This approach uniquely integrates membrane nanofiltration at an optimized pressure of 3.5 MPa, achieving high removal rates of heavy metal ions such as As³⁺, AsO4³⁻, Zn²⁺, Fe²⁺, and Fe³⁺, while reducing waste by 30% and enabling the reuse of sulfuric acid and water in the leaching process, leading to significant cost and resource savings. Practical implications. Implementation of the proposed technology at lead dust processing enterprises reduces the costs of wastewater treatment, reduces the waste volume and allows for the reuse of water and acids in the production process.
Association of cardiac autonomic nerve function with serum zinc, calcium and magnesium in female hypothyroid patients
Authors: Mannan Mahua , Sultana Shamima , Sarkar Bipasha , Sarkar Nandita
Published: September 2024

Background: Hypothyroidism is related to impaired cardiac autonomic nerve activity with altered levels of serum Zinc (Zn), Calcium (Ca) ‍and Magnesium (Mg).Altered Serum Zn,Caand Mg levels are also associated with autonomic imbalance and may raise cardiovascular risk.Heart rate variability (HRV) is an important marker for assessing cardiac autonomic nerve function(CANF). Objectives: To evaluate the association of serum Zn, Cal and Mglevels withCANF in female hypothyroid patients. Methods: This analytical cross-sectional study was conducted on 40 female hypothyroid patients aged 18-45 years. Thirty apparently healthy women were control. Serum Zn, Ca and Mg levels were estimated by autoanalyzer and CANF was assessed by time domain analysis of HRV recorded by Power Lab 8/35 AD Instruments, Australia. Statistical analysis was done by Independent sample‘t’ test, One way ANOVA followed by post-hoc Bonferroni test and Pearson’s correlation coefficient test. Results: Among time domain parameters of HRV, standard deviation of the RR intervals (SDRR), coefficient variation of RR interval (CVRR), SD rate, standard deviation of the difference between successive RR intervals (SDSD), square root of mean squared differences of successive RR intervals (RMSSD), proportion of RR interval with duration >50 ms (pRR50%) were significantly lower (p<0.05) in all  hypothyroid patients as compared to control. On correlation analysis, serum Zn, Ca and Mg were significantly positively correlated with SDSD(p<0.01, p<0.001,p<0.01) RMSSD(p<0.01, p<0.001, p<0.01), pRR50%(p<0.01, p<0.01, p<0.05)and serum Ca was also positively correlated with SDRR(p<0.05) in hypothyroid patients.  Conclusion:Serum ZnCa and Mg were associated with cardiac autonomic dysfunction. in female hypothyroid patients.
J Bangladesh Soc Physiol 2023;18(1): 27-34
Creencias sobre medidas preventivas y desinformación sobre la COVID-19 en una ciudad al sur del Perú
Authors: Pilco-Ferreto Nesstor , Vela-Quico Alejandro Felix , Ponce-Cusi Richard
Published: September 2024

Objetivo: Evaluar las creencias e información sobre la COVID-19 en jóvenes y adultos de Ilo, Perú. Material y métodos: Se realizó una investigación cualitativa utilizando como técnica las entrevistas y como instrumento una guía de entrevista semiestructurada. Para la obtención de los códigos, se trabajó con una aproximación inductiva con preguntas abiertas relacionadas a las medidas de prevención de la COVID-19. Para el análisis de datos cualitativos, se utilizó el programa QDA Miner Lite versión 2.0.9. Resultados: Los jóvenes y adultos muestran conocimientos sobre las medidas de prevención como la vacunación, el uso de mascarillas, el distanciamiento social y el uso de medidas preventivas de acuerdo al riesgo de enfermar. Asimismo, manifiestan desconfianza, molestia y sentimientos de obligación. Las plataformas digitales y las redes sociales fueron los medios de información preferidos, así como la opinión de los especialistas. Conclusiones: En este estudio predominó una desconfianza sobre las vacunas, influenciada por la rapidez de su desarrollo y la falta de información clara sobre su eficacia, así como en el uso de las mascarillas y el distanciamiento social. La desinformación a través de redes sociales ha contribuido a la desconfianza y escepticismo.
Pendampingan Komunitas Belajar Mini Produktif SDN Kolpajung 2 Pamekasan Melalui E-Kombel Sebagai Upaya Mewujudkan Ekosistem Pendidikan Inklusif
Authors: Zayyadi Moh , Lanya Harfin , Linarsih Yanti , Mansyur Muhammad Umar , Rizqiyah Tsalitsatur , Rochmadyan Nabillah Ayuditya
Published: September 2024

Tujuan pengabdian ini adalah memberikan pendampingan komunitas belajar mini produktif SDN Kolpajung 2 Pamekasan melalui E-Kombel sebagai upaya mewujudkan ekosistem pendidikan inklusif.  Kegiatan ini dilaksanakan di SDN Kolpajung 2 Pamekasan dengan fokus pada implementasi komunitas belajar. Metode pelaksanaan kegiatan yang digunakan dalam pengabdian kepada masyarakat adalah refleksi awal, perencanaan, perancangan E-Kombel sebagai inovasi, lokakarya atau pelatihan, implementasi IPTEKS, pendampingan dan evaluasi, serta keberlanjutan program. Dengan kegiatan pendampingan ini, sekolah sangat terbantu dalam pelaksaaan komunitas belajar, baik komunitas belajar internal maupun secara eksternal. E-Kombel sebagai aplikasi berbasis IT yang sangat efektif untuk menambah waktu terbatas di Sekolah dapat dilaksanakan di rumah. E-Kombel menjadikan komunitas lebih keren dan canggih dan dokumen administrasi tersimpan lebih aman daripada secara manual. Ada beberapa saran dan masukan dari peserta pengabdian adalah adanya diharapkan bisa lebih banyak lagi pengaplikasian E-kombel untuk mewujudkan ekosistem Pendidikan Inklusif di sekolah
The Correlation of PD-L1 Overexpression With Tumor Budding In Cervical Carcinoma
Authors: Lestari Desak Putu Oki , Analysa Analysa , Armerinayanti Ni Wayan , Riasa I Nyoman Putu , Artha I Gusti Alit
Published: September 2024

Background: Several studies have proven the relationship between PD-L1, which is known as an immunotherapy target, and poor prognosis. The presence of a tumor budding (TB) group tumor outside the main tumor is also associated with a poor prognosis. The purpose of this study was to determine the relationship between PD-L1 and the grade of TB in cervical carcinoma. Methods: The design of this research is a case-control study with a retrospective approach. The sample is from a paraffin block of the primary cervical cancer tumor from the results of surgery in Balimed Denpasar Hospital between 2020 and 2023. From the statistical formula for the case-control study, a minimum sample of 15 is obtained for the case group with the criteria of high-grade TB, while 15 people were in the control group with low-grade TB. Immunohistochemistry (IHC) PD-L1 is positive if the membrane or cytoplasm is brown, and is negative if there is no brown color on the membrane or cytoplasm. Inferential statistics were used to evaluate the relationship between PD-L1 overexpression and low- and high-grade TB in cervical carcinoma using a chi-square test. Results: The results of this research revealed (p = 0.273) that there was no correlation between PD-L1 expression and high- and low-grade TB. Overexpression of PD-L1 was associated with a 2.250-fold increased risk of high-grade TB (OR = 2.250 with a 95% confidence interval of 0.103–1.915). Conclusions: The severity of TB does not correlate with PD-L1 expression. The functions of PD-L1 and other variables in the carcinogenesis of TB development are the cause of this weak association.
Necrosis area, Tumor Size, and Lymph Node of Breast Cancer
Authors: Laili Kharima , Pratiwi Sari Eka , Ilmiawan Muhammad In'am , Trianto Heru Fajar , Fitrianingrum Iit
Published: September 2024

Background: Breast cancer is the leading cause of cancer deaths in women worldwide in 2020. The high mortality rate is often influenced by various reasons, one of which is patients's prognosis. One of the prognostic factors is necrosis area, caused by hypoxic tumor tissue that can affect tumor growth and metastasis. Therefore, this study aims to determine the relationship between necrosis area with tumor size and lymph node metastasis in breast cancer patients. Methods: This study was an observational analytic with a cross-sectional approach. This research was conducted at the Anatomical Pathology Laboratory of Dr Soedarso Pontianak General Hospital and the Microscopy Laboratory of the Faculty of Medicine Tanjungpura University from September until November 2022. The study sample was 55 slides of Formalin-Fixed Paraffin-Embedded (FFPE). The study was conducted by observing the preparations under a microscope and then analyzed using ImageJ and SPSS software. The independent variable in this study was the necrosis area in the tumor microenvironment, and the dependent variables were tumor size and lymph node metastasis in breast tissue. Results: All study samples were female patients with invasive ductal carcinoma. Breast cancer tends to occur in patients aged 48-55 years. The highest percentage of necrosis area was 21% and the most diagnosed breast tumor size and lymph node metastasis were stage T4 and stage N2. Spearman's rho correlation test showed that there was no relationship between necrosis area and tumor size (p = 0.122; r = 0.16) and lymph node metastasis (p = 0.637; r = 0.18). Conclusions: There is no correlation between necrosis area with tumor size and lymph node metastasis of breast cancer patients in the Anatomical Pathology Laboratory at Dr Soedarso Pontianak General Hospital.
Optimizing Prostate Cancer Radiotherapy: Advanced Machine Learning in Virtual Patient-Specific Plan Verification-Review Study
Authors: Komalasari Rita
Published: September 2024

Background: Virtual patient-specific plan verification in radiotherapy is critical to ensure precise dose delivery while minimizing healthy tissue exposure, particularly in prostate cancer treatments. Prior studies, however, have overlooked the physical implications of predictor features and lacked comprehensive decision support tools, leading to gaps in understanding and practical application. This research aims to bridge these gaps by providing a nuanced understanding of predictor features, exploring advanced automatic feature extraction methods, emphasizing model reliability, and proposing a comprehensive decision support tool. Our objective is to optimize radiotherapy protocols, ensuring safer and more effective treatments for patients undergoing prostate cancer therapy. Methods: This research employs a literature review approach. An extensive literature study served as the foundation. Results: Our study reveals that understanding the physical implications of predictor features significantly enhances prediction accuracy. Utilizing Convolutional Neural Networks (CNN) models for automatic feature extraction improves prediction performance, providing robust and transferable results. Conclusions: By emphasizing model reliability through the integration of treatment plan parameters, our approach ensures stable predictions across diverse patient cases. The proposed decision support tool offers clinicians detailed insights into predicted dose deliverability, facilitating informed decision-making for patient-specific treatment plans. Through these advancements, our research contributes to the optimization of radiotherapy protocols, ensuring safer and more effective treatments for patients undergoing prostate cancer therapy.
Identification of CDH4 Gene Copy Number Alteration and Its Association with Clinical Profile of Colorectal Cancer Patient
Authors: Ayu Dewi Ni Nyoman , Rompis Andreliano Yosua , Mulyawan I Made , Ekawati Ni Putu , Sun H Sunny
Published: September 2024

Background: The genes cadherin 4 (CDH4), Kirsten rat sarcoma viral oncogene homolog (KRAS), V-Raf murine sarcoma viral oncogene homolog B (BRAF), and microsatellite instability (MSI) each play a role in the development of colorectal cancer (CRC). CDH4 gene is located in chromosome 20q13.33 and its amplification or gain is the earliest mutational event found in the majority of CRC and colon polyps. This study aimed to identify copy number alteration in the CDH4 gene and its association with the clinical profile of CRC patients, including gender, age, tumor location and differentiation, frequency of BRAF and KRAS mutations, and MSI status. Methods: The DNA was extracted from 50 tumors and adjacent normal tissues based on the manufacturer’s instructions. Detection of MSI status was carried out by pentaplex polymerase chain reaction (PCR) and PCR products were size separated by capillary electrophoresis (CE) using an ABI 310 Genetic Analyzer. Both KRAS and BRAF mutations were identified by PCR and sequencing while CDH4 copy measurement was measured using TaqManTM Copy Number Assay. Results: Our findings showed 22 (44%) samples with no changes in the copy number of CDH4 gene. Interestingly, 21 (42%) cases had an amplification of the CDH4 gene or CDH4 gene gain, and seven (14%)  cases decreased in CDH4 gene expression or CDH4 gene loss. We found an association between changes in the CDH4 gene and gender (p=0.001). However, there was no association between changes in the CDH4 gene and age (p=0.979), tumor location (p=0.145) and differentiation (p=0.648), the frequency of BRAF (p=0.171) and KRAS mutations (p=0.184) and MSI status (p=0.923). Conclusions: Copy number alteration in CDH4 gene in CRC patients and this alteration is significantly associated with gender. Further studies with a larger number of samples are essential to confirm this result and to identify the cause of CDH4 copy number alteration and its biological significance.
IInduction of G2/M Phase Block and Apoptosis by Kaempferol in Human Sarcoma Cells
Authors: Ishiki Manabu , Yoshii Miho , Kanamori Masahiko
Published: September 2024

malignant cells has interested us to seek new strategies for the treatment of sarcoma. Flavonoids have been recently claimed to exert anti-cancer effects. We focused on the flavonoid kaempferol, to determine whether it induces apoptosis of sarcoma cells in vitro. Methods: We examined cell growth using a CCK-8 assay, morphology, cell cycle analysis, and the apoptosis or differentiation effects of kaempferol on cultured human osteosarcoma MG-63 cells. All experiments were performed at least three times in duplicates. The ANOVA and independent sample t-test were used for the comparison of the continuous variables Results: Kaempferol (50 μM), adversely affected the proliferation of MG-63 cells. Anti-proliferative action of kaempferol appeared to be linked to apoptotic cell death based on the morphological changes depicting nuclear fragmentation. Cell cycle analysis demonstrated the induction of G2/M phase arrest and an enhanced sub-G1 population. However, the intracellular alkaline phosphatase (ALP) activity was observed to have been stimulated. This apoptosis might be associated with cell differentiation of the cells in the early stage. Conclusions: This study demonstrates that kaempferol inhibited the growth of MG-63 cells in vitro. G2/M phase arrest and induction of intracellular ALP activities in the early phase are observed. These findings indicate that kaempferol may present as an additional pharmacological tool for the treatment of human sarcoma cells.
Marginal Excision as a Surgical Treatment for The Schwannoma of Posterior Aspect of Femur: A Case Report
Authors: Raditya Risang Haryo , Wiratnaya I Gede Eka
Published: September 2024

Introduction: Schwannoma is a benign nerve sheath neoplasm attached to a peripheral nerve that often develops in the middle-aged population. It usually presents as an asymptomatic mass at first but can be transformed into a pain, swelling, neurologic, or mechanical symptom in several patients. In this study, we are reporting a case of a schwannoma of the posterior aspect of the thigh, in a young adult male. Case Presentation: We reported a 31-year-old male complained of sharp pain, tingling sensation, and mechanical block in the posterior aspect of the right thigh. Radiological imaging showed the tumor of the posterior aspect of the right thigh, with associated soft tissue edema, the cortex is not invaded. Surgical resection was performed on the patient and the tumor was excised with marginal excision surgery technique. Conclusions: The schwannomas of the femur can successfully be excised with no postoperative complications. There is no sign of a recurrent tumor in six months after the procedure.
Characteristics and Survival of Patients with WHO Grade 4 Diffuse Glioma in Dharmais National Referral Cancer Hospital
Authors: Tadjoedin Hilman , Suryana Kresna Dharma , Rosalina Rosalina , Hartono Bryan Arista , Widarta Oskar Ady , Dewin Nikrial , Andriani Rini
Published: September 2024

Background: The WHO grade 4 diffuse glioma are extremely aggressive and account for over 60% of adult Central Nervous System (CNS) tumors. The diagnosis and management pose significant challenges due to the need for comprehensive evaluation and holistic treatment approaches. This study aims to determine the clinical characteristics of WHO grade 4 diffuse glioma in Indonesia and the overall survival as a secondary goal. Methods: This is a retrospective cohort study of all WHO grade 4 glioma patients from 2017 to 2022 at Dharmais National Cancer Hospital, Jakarta, Indonesia. Demographic characteristics were presented descriptively. Kaplan-Meier plot was used to evaluate the median survival. Results: Twenty-eight patients were eligible for this study. The median age group is 45 years old, with equal male and female prevalence. Headache was the most prevalent primary symptom. The therapy following surgery was radiotherapy (RT) with chemosensitizer (82.1%) and RT alone (14.3%) with both followed by adjuvant chemotherapy. There was one patient (3.6%) underwent palliative therapy. The median survival of all patients was 10 months, whereas 10 months in RT with the chemo-sensitizer group and 1 month in RT only group. There was no statistically significant difference between RT with and without chemotherapy sensitizer in terms of survival rates. Conclusions: Our study reports a younger median age of WHO Grade 4 diffuse glioma. Male subjects were equivalent to females. Median OS was 10 months and were longer in RT with the chemosensitizer group. Further multicentered and at the genetic level investigation was needed, to achieve optimal outcomes.
THE PROBLEM OF THE DEVELOPMENT AND FEATURES OF STRESS RESISTANCE OF MILITARY OFFICERS OF THE NATIONAL GUARD OF UKRAINE
Authors:   The National academy of hte National Guard of Ukraine, Voloshko Serhii
Published: September 2024

A theoretical generalization of the problem of stress resistance of military personnel was carried out. The essence, psychological features of modern socio-psychological technologies for the formation of stress resistance of servicemen undergoing military service in the units of the National Guard of Ukraine under the influence of professional and psychological factors are determined.
LEGAL REGULATION OF THE PROCEDURE FOR TREATMENT WITH PRISONERS OF WAR DURING MARTIAL LAW
Authors:   National Defence University of Ukraine, Kyshkan Vadym
Published: September 2024

The article examines the norms of international humanitarian law in force in Ukraine regarding prisoners of war and the history of their implementation in the Ukrainian legal field. A thorough analysis of the norms of international humanitarian law and their implementation in national legislation is made. The legal regulation of the treatment of prisoners of war during martial law is considered. Attention is focused on the treatment of prisoners of war during martial law or hostilities, observance of their rights and performance of their duties. Threats of possible violations of the rights of prisoners of war are identified. In particular, it is noted that prisoners of war may be subjected to torture and ill-treatment, and may be used as labour without providing them with proper working conditions. The main reasons for the violation of the rights of prisoners of war are given: military operations, unwillingness to comply with international law, and imperfect national legislation. The article identifies the importance of compliance with international law on the treatment of prisoners of war. In order to address the problem of violations of the rights of prisoners of war, it is necessary to ensure compliance with international law, improve national legislation, and create mechanisms for monitoring the observance of the rights of prisoners of war.
APPLICATION OF METHODOLOGICAL PROVISIONS OF MANAGEMENT CONSULTING DURING INSPECTIONS OF MILITARY UNITS OF THE NATIONAL GUARD OF UKRAINE
Authors:   National academy of hte National Guard of Ukraine, Osypenko Stanislav , Zhelnovach Oleksandr ,   National Academy of the National Guard of Ukraine, Pysarevskyi Serhii ,   National Academy of the National Guard of Ukraine
Published: September 2024

The expediency of applying the methodological provisions of the theory of management consulting to improve the efficiency of inspections of military units is analysed. The article considers a step-by-step sequence of inspections with consideration of the theory of management consulting. Organisational and methodological recommendations for each stage of the audit are proposed.
PROSPECTS FOR CREATING A MILITARY POLICE IN UKRAINE TO ENSURE DISCIPLINE AND LEGALITY AMONG MILITARY PERSONNEL: GENESIS, CURRENT STATE AND PLACE IN THE STRUCTURE OF THE SECURITY AND DEFENCE SECTOR
Authors:   The National academy of hte National Guard of Ukraine, Morkvin Dmytro , Batsamut Volodymyr ,   National Academy of the National Guard of Ukraine, Hokh Iryna ,   National Academy of the National Guard of Ukraine
Published: September 2024

The author examines the prospects of creating military police in Ukraine. The differentiation of the functions of the military police from the law enforcement functions of other formations and the military law enforcement service has been conducted. The draft law on the establishment of the military police is analyzed. The author examines regulatory legal acts and provides proposals for amending them in the context of the creation of the military police. It is emphasized that the military police should become a powerful formation for combating crime in the security and defence sector, as well as for preventing disciplinary and administrative offences committed by military personnel. The international experience of military police activities has been presented. It is noted that the activities of the military police must comply with NATO standards. It is determined that the most appropriate way is to create military police within the structure of a military formation with law enforcement functions � the National Guard of Ukraine � in order to comply with the principle of independence and impartiality, as well as taking into account the experience of NATO member states.
CURRENT ISSUES OF THE REAR SERVICES TECHNICAL MEANS APPLICATION BY THE UNITS OF THE NATIONAL GUARD OF UKRAINE WHILE PERFORMING ASSIGNED TASKS
Authors:   National academy of hte National Guard of Ukraine, Pavlenko Serhii , Smahin Oleh ,   National Academy of the National Guard of Ukraine
Published: September 2024

The main reasons for the emergence of current problems of the use of technical means of logistics services by the National Guard of Ukraine units while performing the assigned tasks. The functions of the National Guard of Ukraine are analysed, including: separate and emphasise the specificity of the tasks performed in comparison to other military and law enforcement formations; demonstrate the similarity of the functions of the National Guard of Ukraine to those of the Armed Forces of Ukraine. The article summarises the current problems of technical means used by logistics services of the National Guard of Ukraine units while performing the assigned tasks.
PECULIARITIES IN SOCIOMETRICALLY VARIED SERVICEMEN'S ATTITUDES TOWARDS LEADERSHIP MANIFESTATIONS IN MILITARY TEAMS
Authors:   National academy of hte National Guard of Ukraine, Tovma Ihor , Tovma Mykola ,   National Academy of the National Guard of Ukraine
Published: September 2024

An analysis of theoretical scientific research on the state of leadership in modern military units, including the proposal of constructive manifestations of leadership identified from the professional experiences of the servicemen in the National Guard of Ukraine, along with the identification of peculiarities noted between the attitudes of servicemen with different sociometric statuses, specifically in regards to authorities (manifestations of leadership) within military teams.
МОДЕЛЬ ФОРМУВАННЯ ГОТОВНОСТІ МАЙБУТНІХ ФАХІВЦІВ З ТУРИЗМУ ДО ДІЯЛЬНОСТІ У ПРОФЕСІЙНОМУ ІНФОРМАЦІЙНОМУ ПРОСТОРІ
Authors: Парій Світлана
Published: September 2024

The presented material of this study is a justification and experimental verification of the effectiveness of the model of training future tourism specialists for activities in the professional information space. The basis of the developed model of training future specialists is their readiness for activities within the information space of tourism. According to the hypothesis and purpose of the research, the readiness of future specialists to work in the professional infospace is a multidimensional phenomenon and includes a number of individual components, including motivational, cognitive, technological, personal, and complex indicators.
The results of checking the effectiveness of the developed model of formation of readiness are presented through indicators of the level of formation of the components of the readiness of future tourism specialists for activities in the professional information space and a comprehensive indicator. The distribution of students according to the following levels of formation of readiness components at the ascertainment and control stages of the research was determined: creative, reconstructive, reproductive. The probability of differences in the results of students in the control and experimental groups at both stages of the study was assessed using the Fisher angular transformation criterion.
It has been proven that, according to the results of the control section, the indicators of the formation of the components and the comprehensive indicator of the readiness of future specialists of the control and experimental groups at the end of the study have statistically significant differences. This indicates the presence of a close relationship between the implemented measures of the formative experiment (theoretical and practical mastering of the special course, individual content modules and topics from information systems and technologies in tourism) and the improvement of the formation of the components of the readiness of future tourism specialists to work within the professional space of tourism. The average indicators of the formation of readiness components and the corresponding complex indicator were significantly higher among the students of the experimental group. The effectiveness of the hypothesis formulated at the beginning of the research and the effectiveness of the model of training future tourism specialists for activities in the professional information space have been fully confirmed.
НАВЧАЛЬНЕ ПРОГРАМУВАННЯ В КОНТЕКСТІ РЕФЛЕКСІЇ РОЗУМОВИХ ДІЙ ТА ЇХ ФОРМАЛІЗАЦІЯ ПРОГРАМНИМ КОДОМ
Authors: Головін Микола , Головіна Ніна , Гузачов Дмитро
Published: September 2024

The paper examines the problem of improving programming learning through optimization of reflection accompanying the writing of software code. Reflection, as control of the logic of thinking, is an important mechanism of critical thinking in educational and professional activities. The purpose of this research is the formation of optimized, conceptual, concise schemes of reflection, which will allow to successfully cope with the tasks of educational practical programming. To realize the goal, an analysis of educational practical activities in programming was carried out in the context of their reflection on the example of creating a computer model of a simple physical phenomenon. The choice of programming as an activity for analyzing critical thinking reflection is due to the fact that this activity is well formalized. The essence of critical thinking reflection is revealed here in a refined and transparent form. Modeling gives the thinking process its own contrast, because in mental activity, in addition to algorithmic senses, additional physical ones also appear. Programming a model of a physical process here is a kind of research ground. Reflection is considered through the prism of cyclical mental processes in terms of formal logic with reference to the evolution of the structure of declarative knowledge. The final instance of this analysis was the formalization of reflection actions in laconic schemes, both the processes themselves and the structure of knowledge. An important part of the work is the connection of mental actions with the corresponding materialized activity. This relationship was also succinctly depicted on the corresponding diagram. The clear, short, expressive formalization of critical thinking actions presented in the work, in connection with materialistic actions, in laconic schemes could be used by education seekers to optimize learning and form protocols of abstract-logical and cause-and-effect thinking. The developed reflection schemes can be considered as a methodical means of learning that allows you to avoid cognitive traps and optimize educational activities both in the field of practical programming and in natural fields of knowledge, where practical actions to create or debug artificial objects of high complexity are expected.
ВИКОРИСТАННЯ ВІРТУАЛЬНОЇ ЛАБОРАТОРІЇ LABSTER ДЛЯ ВИВЧЕННЯ ХІМІЇ В ТЕХНІЧНОМУ УНІВЕРСИТЕТІ
Authors: Гулай Ольга , Шемет Василина , Мороз Ірина , Саварин Павло , Кабак Віталій
Published: September 2024

Immersive virtual labs represent a digital paradigm in education that meets the needs and preferences of today’s students. The main advantage is the ability to conduct laboratory and practical work in the physical absence of educational equipment or the inability to use it, which is especially important in the context of martial law restrictions in Ukraine. The article analyzes the experience of using the Labster web platform, which provides virtual laboratory simulations of natural sciences. The virtual laboratory was used in the educational process of Lutsk National Technical University when teaching chemical disciplines in the autumn semester of the 2023-2024 academic year.
The virtual simulation tasks "Introduction to Groups of the Periodic Table" were offered to students as an alternative option for extracurricular independent work. 146 1st year students were registered, of which 99 (67.8%) completed the test, and 47 (32.2 %) partially passed it. The results of the surveys are presented, the first was conducted immediately after work, the second was a questionnaire on the comprehensibility of the content and the perception of the usefulness of Labster modeling – about three weeks after the completion of the Labster simulation.
Based on the analysis of the answers of students, the main advantages of using a virtual laboratory are established - gaining new educational experience, improving the knowledge and digital skills of students. Virtual simulations increased students' engagement and confidence. The advantage of working in a virtual laboratory is personalized learning. The main obstacles to using Labster are highlighted: low level of English proficiency (Labster does not involve the use of Ukrainian content) and insufficient digital skills to navigate in the virtual space.
It is recommended to use virtual simulations not as a substitute for classroom practical exercises, but as a modern tool to supplement them.
ANALYSIS OF THE RESULTS OF SIMULATIVE MODELLING OF THE INFORMATION SECURITY SYSTEM IN THE CORPORATE NETWORKS OF HIGHER EDUCATION INSTITUTIONS
Authors: Gasimov Vagif , Ismailov Balami
Published: September 2024

The analysis shows that the insufficient level of information security in service networks is the main cause of huge losses for enterprises. Despite the appearance of a number of works to solve this problem, there is currently no unified system for assessing information security. This shows that this problem has not yet been sufficiently studied and relevant. This work is one of the steps towards creating a system for assessing information security in service networks.
The purpose of the work is to develop an algorithm and simulation model, analyze the results of the simulation model to determine the main characteristics of the information security system (ISS), providing the ability to completely close all possible channels of threats by controlling all unauthorized access (UA) requests through the protection mechanism (PM).
To solve the problem, a simulation method was applied using the principles of queuing systems (QS). This method makes it possible to obtain the main characteristics of the ISS from the UA with an unlimited amount of buffer memory (BM). Models, an algorithm and a methodology for the development of ISS from UA are proposed, which is considered as a single-phase multi-channel QS with an unlimited volume of BM. The process of obtaining simulation results was implemented in the GPSS World modeling system and comparative analyzes of the main characteristics of the ISS were carried out for various laws of distribution of output parameters. At the same time, UA requests were the simplest flows, and the service time was subject to exponential, constant and Erlang distribution laws.
Conducted experiments based on the proposed models and algorithm for analyzing the characteristics of the ISS from the UA as a single-phase multi-channel QS with unlimited waiting time for requests in the queue confirmed the expected results. The results obtained can be used to build new or modify existing ISS in corporate networks for servicing objects for various purposes. This work is one of the approaches to generalizing the problems under consideration for systems with an unlimited volume of BM. Prospects for further research include research and development of the principles of hardware and software implementation of ISS in service networks.
The international cooperative relationship model based on social network analysis and game theory
Authors: Zhu Kailin , Ibrahim Ahmad Zubir bin
Published: September 2024

This article regards international cooperative trade as a typical organisational cooperation paradigm and behavioural process. The correlation characteristics between multinational enterprises were studied using dynamic game theory. The focus was on resource dependence and collaborative relationships between different types of enterprises. Cooperation and mutual confrontation are game strategies of international industry collaboration organisations. The expected returns, resource dependence, and realistic collaboration costs determine the final consequences of strategic evolution. Resource dependence affects the rate at which the behavioural decisions adopted by participants tend to reach equilibrium strategies. The diversity of collaborations between firms makes strategic evolution more complex. Finally, this article provides relevant suggestions on international cooperative relations based on social network analysis and game theory.
Grau de concordância entre instrumentos laboratoriais e não-laboratoriais na estratificação do risco cardiovascular
Authors: Andrade Beatriz Pimentel de Oliveira , Fialho Milena Henriques , Gomes José Victor Ribeiro Silva , Ruiz Kananda Oliveira Garcia , Amaral Mariela Svízzero , Drumond Rafael Fonseca , Ribeiro Vitor de Oliveira , Damázio Laila Cristina Moreira
Published: September 2024

Objetivo: Avaliar o grau de concordância entre o Escore de Risco Cardiovascular de Framingham e a calculadora do programa HEARTS, em sua versão com uso do IMC, na estratificação do Risco Cardiovascular (RCV) em pacientes diabéticos e/ou hipertensos na Atenção Primária à Saúde (APS). Metodologia: Estudo transversal, exploratório e epidemiológico, com uma amostra de conveniência de 89 indivíduos selecionados em 10 Unidades Básicas de Saúde de um município brasileiro de médio porte. Os escores foram aplicados nos pacientes e o grau de concordância foi analisado através do Coeficiente Kappa. A análise bivariada das variáveis independentes foi realizada por meio do Qui-Quadrado. Resultados: Na população estudada, houve predominância das faixas de risco “elevadas” (>10%), para ambos os sexos em nas duas escalas. A calculadora HEARTS apresentou baixo poder de discriminação dos pacientes com riscos cardiovasculares mais elevados (>10%). A análise bivariada mostrou relação positiva entre faixa etária geriátrica, pressão arterial elevada e presença de hipertensão em mulheres com RCV mais elevado no ERG,  mas não encontrou correlações na HEARTS. O índice de concordância Kappa entre os dois escores foi de 0,06. Conclusão: Houve concordância mínima entre os escores, além de um comportamento diferente em relação aos critérios utilizados no cálculo do RCV. Torna-se importante o incentivo de estudos nacionais para calibrar e validar calculadoras de RCV que correspondem à realidade brasileira, de modo a tornar acessível ferramentas facilitadoras para o cálculo do RCV na APS.
Eficácia das terapias cognitivo-comportamentais no tratamento do transtorno de estresse pós-traumático: Uma revisão de literatura
Authors: Aragão João Victor Alves de , Cruz Mário Jorge Souza , Oliveira Bianca Cardoso , Souza Júlia da Cunha Pereira de , Gonçalves Rodrigo Vitorino , Gama Maria Eduarda Carvalho Nogueira da , Del’Arco Gabriela Carvalho , Brigido Carlos Eduardo Pinheiro Leal , Silva Ana Clara Guerra , Cruz Lanna Luiza Ferreira  da , Costa Henrique Souza , Hannesch Alexia
Published: September 2024

O Transtorno de Estresse Pós-Traumático (TEPT) é uma condição psiquiátrica grave que pode surgir após a exposição a eventos traumáticos, como violência, desastres naturais ou acidentes graves. As Terapias Cognitivo-Comportamentais (TCC) têm sido amplamente estudadas e recomendadas como tratamento de primeira linha para o TEPT devido à sua eficácia comprovada na redução dos sintomas. Esta revisão de literatura tem como objetivo examinar a eficácia das TCC no tratamento do TEPT, focando em modalidades específicas como a Terapia de Exposição Prolongada (TEP), a Terapia Cognitiva (TC) e a Terapia de Processamento Cognitivo (TPC). A TEP envolve a exposição gradual e controlada aos estímulos traumáticos, enquanto a TC foca na reestruturação cognitiva para alterar crenças disfuncionais relacionadas ao trauma. A TPC combina elementos de exposição e reestruturação cognitiva, ajudando os pacientes a processar memórias traumáticas e modificar pensamentos negativos. Estudos recentes indicam que essas abordagens são eficazes na redução dos sintomas de TEPT, como reexperiência, evitação e hipervigilância, e na melhoria da qualidade de vida dos pacientes. No entanto, a eficácia pode variar dependendo de fatores individuais, como a gravidade do trauma e a presença de comorbidades, e contextuais, como o ambiente de tratamento. Esses achados destacam a necessidade de personalização do tratamento e de mais pesquisas para otimizar as intervenções e garantir que sejam acessíveis e eficazes para diversas populações.
Nanomateriais à base de carbono: Oportunidades e desafios na Medicina
Authors: Fonseca Lara Cruvinel , Figueiredo Bárbara Queiroz de , Caixeta Bruna Silveira , Faria Ana Paula Gonçalves , Caixeta Marcelo Eduardo
Published: September 2024

O carbono era um dos elementos mais importantes para a Terra e os humanos. Havia muitos alótropos diferentes do elemento carbono. O grafeno, que era bidimensional e tinha um átomo de espessura do elemento carbono, era um nanoporo natural e o material mais pesquisado do século XXI. O grafeno era um dos materiais mais importantes usados ​​no campo dos nanomateriais. Ele tinha propriedades térmicas, ópticas, elétricas e mecânicas superiores. Era um material extraordinariamente leve e forte entre todos os materiais conhecidos, e também era um material que poderia ser facilmente modificado para a área desejada. Neste artigo, foi visto que o nanoporo de grafeno e o material de grafeno estariam entre os materiais mais importantes no campo da saúde no futuro. No campo da saúde, esse grafeno à base de carbono e a descoberta de nanoporos de grafeno foram pesquisados ​​e usados ​​por muitas disciplinas, como o tratamento de muitas doenças, aplicações de administração de medicamentos, biotecnologia, tratamento de doenças hereditárias e até mesmo para criar biossensores a serem usados ​​para detectar doenças. O grafeno e seus derivados eram materiais significativos que podiam ser usados ​​no campo da saúde e se tornou o material mais essencial dos últimos tempos, pois sua estrutura mostrou estabilidade ao entrar no corpo. Era compatível com células e podia se mover rapidamente nas células com sua natureza pequena e porosa. Devido à sua estrutura, esse material era a única substância que poderia substituir todos os materiais usados ​​no campo da saúde.