bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk assessment in biomedical laboratories – occupational safety and health aspects
Authors: Pašalić Arzija , Šegalo Sabina , Maestro Daniel , Biščević-Tokić Jasmina , Jogunčić Anes , Panjeta Mirsad , Hasanefendić Berina
Published: December 2022

Introduction: Laboratory personnel (LP) represent a high-risk group of healthcare workers for whom the primary laboratory environment and specific work activities are a major source of potential exposure to health hazards. This study aimed to evaluate the developed matrix and assess risk based on self-assessment.
Methods: This multicenter, qualitative, and cross-sectional study was conducted on LP employed in biomedical laboratories. The respondents were divided into groups according to their territorial affiliation. The data collection tool used was a six-area questionnaire distributed online through a network of professional associations. For the risk assessment, a matrix was developed with scores ranging from 0 to 650, dividing the risk level into four categories. Descriptive and inferential statistical methods were used for the statistical analysis.
Results: The developed model combined the classification of risk and risk factors with a certainty of p < 0.001. The regression analysis showed that working conditions had the greatest influence on overall risk, followed by physical, biological, and physical hazards. Of the 640 respondents, the medium risk category was the highest in European Union (EU) countries (81.2%). Comparing the values in the high-risk category between the Bosnians and Herzegovinians (BiH) group and the Republic of Serbia, Republic of Northern Macedonia, and Montenegro (SCM) group with the EU group, a doubling (16.6%: 36.7%) and tripling (16.6%: 52.1%) of the proportion was found, respectively (p < 0.001). Overall, 1.7% of the LPs from BiH fell into the high-risk category.
Conclusions: The designed matrix provides a reliable basis for identifying risk predictors in the study population and can serve as a useful tool for conducting risk assessments in biomedical laboratories. The results of the risk assessment indicate significant differences between the studied groups and highlight the need for increased control of BiH workplaces through new regulatory requirements.
Romances e provérbios na literatura portuguesa quinhentista: o caso de «erros por amores»
Authors: Sirgado Ana
Published: December 2022

The verse «que los yerros por amores | dignos son de perdonar» is a constant presence in the Portuguese literature of the 16th century, more or less recreated from a discursive and semantic point of view, and there is still evidence of its use in the 17th century alluding to «Media noche era por filo». However, in cases where this expression appears separated from other elements of the ballad that stars Conde Claros, in works such as Comédia Eufrosina or Comédia Ulissipo by Jorge Ferreira de Vasconcelos or even Comédia dos Estrangeiros by Francisco Sá de Miranda, we might be in the presence of the proverb collected by Gonzalo Correas in the Vocabulario de refranes y frases proverbiales. This study seeks to determine the autonomous circulation of this expression in Portugal, also in the light of new data published here for the first time.
Storytelling as Media Literacy and Intercultural Dialogue in Post-Colonial Societies
Authors: Cruz Maria Teresa , Miranda Madalena
Published: December 2022

This article reflects upon digital storytelling and collaborative media practices as valuable tools for reassessing memory, questioning identity discourses, and unveiling the cultural diversity of contemporary societies. The digital age allows for a constant re-reading and re-mediation of cultural archives by ordinary citizens, namely by younger generations, and for the production and dissemination of alternative narratives about the present. These are crucial opportunities for post-colonial societies to overcome silences around difficult memories that hinder a collective reappropriation of the past, confront some of the current issues on ethnical diversity, and discrimination and reimagine a more inclusive identity. However, taking advantage of this opportunity implies fully recognizing the role of media technology in shaping memory, social individuation and establishing networks, making media literacy and media education crucial aspects of cultural dialogue. Based on the experience of a citizenship project about the post-colonial condition and Afro-European interculturality, this essay reflects on digital storytelling, and co-creative practices as relevant literacy and education strategies for furthering interculturality in contemporary societies.
Panorama sobre turismo de bem-estar: status atual de pesquisas e temas emergentes
Authors: Santos-Silva Letícia Cynara , Souza-Neto Valério , Mayer Verônica Feder
Published: December 2022

O turismo de bem-estar refere-se às relações resultantes de uma viagem que tem como motivo e com esforços intencionais, por parte da oferta e demanda, apoiar e promover a saúde e bem-estar, permitindo a melhora do físico, psicológico, espiritual e/ou social das pessoas. Por conseguinte, mudanças e novas tendências nas condições de oferta e demanda do turismo de bem-estar e novas formas de turismo podem estimular atividades turísticas futuras. Entretanto, a falta de literatura nacional evidencia a necessidade de pesquisa desse tema relevante para o turismo, que se configura ainda mais importante após o mundo ter sido impactado por uma pandemia que afetou o bem-estar geral. Diante desse cenário, o presente artigo objetiva conseguir um panorama das pesquisas de turismo de bem-estar com espectros, resultados e tendências. Para isso, conduziu-se uma revisão sistemática da literatura na busca de artigos científicos nas plataformas Web of Science, Publicações de Turismo e Google Scholar. Os resultados da pesquisa mostraram que a maioria dos artigos se concentrou em trabalhos com turistas ou empreendimentos em países asiáticos, uma vez que mencionam sobre o turismo de bem-estar na perspectiva da oferta e ponto de vista recreativo e utilizam como principais termos turismo de bem-estar, turismo médico e turismo de spa. Ainda mais, observou-se um grande número de publicações nos anos de 2019 e 2021, enquanto o crescimento mais expressivo foi o da revista Journal of Travel & Tourism Marketing e o número mais alto de publicações no ano de 2021 foi a revista Sustainability.
СONTINUUM LEXICAL → LEXICAL-SYNTACTIC → SYNTACTIC SYNONYMY IN THE PROCESS OF CAUSATION OF LANGUAGE-SPEECH ACT (based on the material of modern French fiction)
Authors:   H. S. Skovoroda Kharkiv National Pedagogical University, Lepetiukha Anastasiia
Published: December 2022

The article is dedicated to the studies of lexical, lexical-syntactic and syntactic synonymies from the standpoint of mentalist theory of the French scientist G. Guillaume who presented the process of causation of language-speech act in the form of the trine: mental operations → language → discourse at the level of each component of which function the psychomechanisms (conscious and unconscious cognitive polyoperations of formation and actualization of linguistic signs) ensuring intercepts (stops) of the movement of thought during which simple and complex linguistic signs are formed. It is found that the synonymic relations appearing on the first intersept of the movement of thought are manifested in the discourse in the form of lexical synonymy; syntactic synonymy of the level of syntagma is created on the second intersept and syntactic synonymy of the level of utterance – on the third intersept of the movement of thought; lexical-syntactic synonymy is formed if lexical synonymy transitions to synonymy of the level of syntagm or proposition. As a result of the analysis of the examples of French authors’s prosaic works of the XXth – the beginning of the XXIst centuries at the level of lexems the absolute synonymy characterized by the symmetry of significative and denotative meanings of the lingua-discursive sign, the partial synonymy inherent to lingua-discursive signs with semantic nuances and the desynonymy (pseudosynonymy) (designation of one referent by the lingua-discursive sign with the asymmetry of significative and denotative meanings in the language and in the discourse) are revealed. The conducted analysis allows to make a conclusion that at the level of lexical‑syntactic and syntactic synonymies only the partial synonymy exists because in mono- and polypredicative utterances with lexical-syntactic and syntactic synonymies the complex of virtual (linguistic) referents with the implication of some components and the focalization of new referents is actualized.
Exploring the Current State of North American Graduate Archival Education
Authors: Zhang Jane , Poole Alex H.
Published: December 2022

This article analyzes 65 North American graduate archival education programs' course listings against current professional standards as crystallized in the 2016 Guidelines for a Graduate Program in Archival Studies (GPAS). The study addresses the following research questions: 1) What types of programs list graduate archival education courses?, 2) What types of courses do these graduate archival programs currently list?, 3) To what extent do archival programs' courses conform to GPAS?, and 4) What are the implications of a program's conforming or not conforming to GPAS?

The authors' findings indicate an overriding tendency for graduate archival education programs to be hosted by LIS programs, especially under the auspices of iSchools. They identified a great diversity of graduate archival education programs and course listing combinations. Most important, they analyzed the archival curriculum coverage of 65 graduate archival programs to discern conformance with GPAS curriculum requirements. Although their findings may be used by programs for self-study, they also call into question the overall utility of GPAS and suggest the need for a more flexible approach.
Carbon Radiotheraphy For Head and Neck Cancer: Dosimetric Comparison with Photon Plans
Authors: ERKAL Deniz , KUDAY Sinan
Published: December 2022

Radiation therapy is one of the most widely used treatment methods for tumors. The therapeutic use of carbon ions is more advantageous than other radiotherapy techniquies especially photon-based irradiation due to its physical properties and radiobiological effects, and therefore it has received more attention. One of the most important reasons for that carbon ion beams are more effective than photon beams while minimizing the dose in the normal tissues around the target, it offers an improved dose distribution that leads to sufficient dose concentration in tumors. In addition, the carbon beam reaches its maximum at the end of its range, which increases with depth, and due to this feature, it provides a higher biological efficiency. In radiotherapy studies, Monte Carlo simulation is widely used to determine the dose distributions and to obtain the correct properties of the beams. With MC simulation, it helps to understand the relative biological efficiency as well as the spatial model of energy storages. In this study, a geometry with critical organs (skull, brain, nasopharynx and thyroid) based on a MIRD phantom was modeled with the Monte Carlo simulation tool GATE (vGATE 9.0). In this experiment, the tumor was irradiated with different carbon beam energies and photon beams. The aim is to calculate the energy accumulations in the region and surrounding organs with the MC method, and as a result, to show the dosimetric advantages of carbon radiotherapy over photon radiotherapy.
Effects of Deuteron and Alpha Optical Model Potentials on the Production Cross–Section Calculations of Some Radiobromine Isotopes
Authors: ŞEKERCİ Mert , KAPLAN Abdullah
Published: December 2022

The extensive use of radioisotopes in diverse fields, particularly in medical studies for diagnosis and treatment, is one of the outcomes of evolving technology and improved scientific research. Among the various radioisotopes used for medical purposes, an example that can be highlighted considering their properties and utilization possibilities is radiobromine isotopes. It is obvious that both experimental and theoretical studies make significant contributions to the literature on medically relevant radioisotopes. The cross–section, which is the data connected with the occurrence of a reaction, is one of the theoretical metrics that may provide information to researchers. The framework of this study was constructed by taking into account the importance of radiobromine isotopes in medical applications as well as the effects of some parameters that might have an impact on their production cross–section calculations. In this context, the impact of five deuteron and eight alpha optical model potentials, which are available in the 1.95 version of the TALYS code, on the production cross–section calculations of 75-77Br radioisotopes through some (d,x) and (α,x) reactions have been studied. The obtained calculation results were compared visually and numerically with the experimental data available in the literature for each reaction, and the outputs were interpreted.
Searching for New Supernova Remnant Candidates from the VTSS Survey
Authors: BEKLEN Elif
Published: December 2022

The Virginia Tech Spectral Line Survey (VTSS) Galactic Plane Hydrogen-Alpha Survey has the strong ability to search and discover many different types of objects that cannot be identified clearly on red plates and by other Multi-Wavelength Sky Surveys. Here we make a visual search from the VTSS fields with the supportive surveys of Southern Hydrogen-Alpha Sky Survey Atlas (SHASSA) and MDW Hydrogen-Alpha Sky Survey (MDWS) fields, in the Galactic latitude of |b| between -17 ° and 7 ° for several new optical emission nebulae. Seven candidates were chosen as most likely supernova remnant candidates by their physical shapes and the three of all having [SII]/Hα ratio larger than 0.4, found with T100 photometric observations, are considered to be supernova remnant candidates. Comprehensive optical imaging and spectroscopic observations with multi-wavelength observations will help us to identify the types of all these galactic candidates, more precisely.
Predictors of worsening condition before discharge in patients of the gerontopsychiatric hospital.
Authors: Beltceva Iuliia A , Zalutskaya Natalia Michailovna , Neznanov Nikolai Grigorievich
Published: December 2022

Introduction. Hospitalization of an elderly patient in some cases may be associated with such negative phenomena as social and psychological maladjustment, a decrease in the level of daily functioning, the formation of dependence on a hospital and hospitalism. Often in clinical practice there are patients whose condition suddenly worsens just before discharge from the hospital.
The aim of this study was to analyze the dynamics of the patient's condition in the period preceding the planned discharge from the hospital, to identify various clinical options for worsening the condition, and to search for possible predictors of this adverse event.
Materials and methods. Were examined 181 patients of the department of geriatric psychiatry NMIC PN. V.M. Bekhterev included by the continuous method in accordance with the criteria. The main research methods were clinical-psychopathological and clinical-anamnestic.
Results. Deterioration of condition before discharge was observed in 44.8% of the examined patients and was represented by an exacerbation of the leading mental disorder syndrome, the appearance of new symptoms, somatic decompensation, or a combination of these phenomena. Patients whose condition worsened were characterized by longer hospital stays, more medications prescribed, a higher prevalence of hospitalism and compliance violations. Somatic decompensation developed in patients with a shorter duration of mental illness and was associated with a hidden refusal to take medications, for patients with an exacerbation of symptoms of a mental disorder, irregular drug intake and abuse were more typical.
Conclusion. Elderly patients with a long history of hospitalizations and inpatient care options have an increased risk of deterioration before discharge from the hospital, as a result of which these patients need the earliest possible involvement in rehabilitation and psychotherapeutic measures and rational psychological support at the stage of preparation for discharge.
Prevalence of disadaptive eating behavior among sports university students
Authors: Davletova Nailya Сh. , Tafeeva Elena A.
Published: December 2022

BACKGROUND: Numerous studies have proven the importance of studying the actual nutrition of student youth. However, the prevalence of maladaptive eating behavior (EB) among student-athletes and non-athletes remains unexplored.
AIM: to assess the prevalence of maladaptive EB among students of a sports university.
METHODS: a survey was conducted of 768 students of the Volga Region State University of Physical Culture, Sports and Tourism using the Eating Behavior Assessment Scale (EBAS). Statistical analysis of the results was performed using SPSS Statistics v. 19.0 (IBM, USA).
RESULTS: Оnly 41.11.8% of students of a sports university have no signs of maladaptive EB. The presence of deviations according to the subscales of EBAS was revealed in 72.94.5% of martial artists, 57.84.6% of athletes of complex coordination sports and 55.84.2% of cyclic sports, 55.03.2% of players and 59.43.7% of non-athletes. However, no statistically significant gender differences were found. Clinical symptoms of maladaptive EB were detected in 10.32.3% of non-athletes and 8.61.2% of athletes. At the same time, in student-athletes of individual sports, they were detected 1.7 times more often than in team sports (2=22.36; df=9; р=0.008). Psychological characteristics and stereotypes of behavior characteristic of people with maladaptive EB were found in 33.13.6% of non-athletes and 28.51.9% of student-athletes.
CONCLUSION: Among the university sports students, there is a high prevalence of maladaptive EB among combat athletes. Whereas, among athletes, and female athletes of team sports, as well as young men and women who do not participate in sports, clinical symptoms of maladaptive EB have been relatively uncommon, however, psychological and behavioral stereotypes typical of persons with maladaptive EB are more often detected, which can be considered as a high predisposition to the development of such conditions.
Intra-shift and Inter-shift Dynamics of Stress Index of Regulatory Systems in Medical Personnel of Mobile Emergency Medical Teams in Modern Conditions
Authors: Bolobonkina Tatyana A. , Dement’yev Aleksey  A. , Minaeva Natalya V. , Lapkin Mihail M. , Kulagin Pavel A.
Published: December 2022

INTRODUCTION: In conditions of spread of the new coronavirus infection SARS-CoV-2 (COVID-19), the work regimen and working conditions of the mobile emergency medical teams have changed, the range of occupational hazards has expanded, which led to unfavorable alterations in the functional state of the nervous system of workers.
AIM: To study the influence of the professional activity on the functional state of an organism of medical workers of mobile emergency medical teams in conditions of COVID-19 pandemic.
MATERIALS AND METHODS: Parameters of the functional state of an organism of medical workers of mobile emergency medical teams were studied before, after the work and between shifts in the period from May to October 2021. The extent of centralization of the heart rhythm control was evaluated by use of strain index (SI) of regulatory systems. The sample included 67 workers of mobile teams (21 men and 46 women), 16 doctors and 51 paramedics. The average age of workers participating in the study was 36.28 2.82 years.
RESULTS: By the end of shift, in more than half the medical workers of mobile EMT, SI grew by 74.75 units (p = 0,021). The age (2 = 6.467; р = 0.040) and length of service (2 = 6.069; р = 0.049) influenced the distribution of workers with different SI dynamics on the basis of the results of the work shift. By the beginning of the next shift, in 60.71% of workers included into the study, a significant increase in SI was recorded on average by 74.02 (р = 0.001) compared to the beginning of the previous shift. The influence of length of service on the distribution of workers with different dynamics of SI in the successive shifts into groups was recorded (2 = 7.313; р = 0.026).
CONCLUSIONS: The dynamics of the growth of the strain index of regulatory systems indicates low effectiveness of recovery of the functional state of an organism of workers in the period of scheduled rest. The greatest influence on the growth of parameters was exerted by length of service, which indicates the negative impact of working conditions on the functional state of an organism of workers.
Changes in Metabolic Parameters of Rats in Different Age Periods After Prenatal Stress
Authors: Martyusheva Anna  S. , Subbotina Anastasiya  Yu. , Abramova Anastasiya  Yu. , Alekseeva Irina  V. , Pertsov Sergey  S.
Published: December 2022

INTRODUCTION: Currently, biomedical specialists give special attention to studying the influence of stressogenic factors on an organism of a pregnant woman, the embryonic development of the fetus and the subsequent development of offspring in the early and late ontogenesis. It has been found in a number of studies that prenatal stress can lead to reduction of physical activity and hormonal disorders. The factors leading to disorders in regulation of immune and metabolic homeostasis have been identified. Despite considerable interest in the study of the consequences of prenatal stress, its impact on changes in metabolic intensity in different periods of postnatal ontogenesis in animals of different genders has not been sufficiently studied.
AIM: To study parameters of metabolism intensity in different age periods of postnatal ontogenesis in rats offspring of both genders after intrauterine stress load.
MATERIALS AND METHODS: Stress load was modeled in daily forced swimming of pregnant rats at 1012C for 5 min. Oxygen consumption, carbon dioxide excretion (ml/h/kg), and heat exchange (kcal/h/kg) in male and female rats were determined using a Phenomaster automated modular unit (TSE Systems GmbH, Germany) on the 21st, 30th and 60th day of the ontogenesis. Statistical significance of differences between the studied parameters was assessed using Mann-Whitney U-test for independent groups.
RESULTS: The study parameters of intact animals practically did not differ in the suckling (the 21st day) and infantile period (the 30th day), but significantly decreased in the juvenile period of development (the 60th day). It was found that the intrauterine stress did not lead to statistically significant changes in the absolute values of metabolic parameters as compared to the control, but affected the period of appearance of age-related variations of these parameters in male rats. In these animals, the volumes of oxygen consumption, carbon dioxide excretion, and the level of heat radiation reduced as early as in the infantile period (as compared to 21-day-old rats) and reached the minimum level by the 60th day of the postnatal ontogenesis. In female rats subjected to intrauterine stress, changes in the study parameters in different periods of life were similar to those of intact animals.
CONCLUSION: Therefore, prenatal stress modeled by swimming of female parents in cold water, has a modulating effect on age-related dynamics of metabolic parameters of male rats, which was manifested by the decrease in these parameters in the earlier period of development.
The Role and Significance of Polymorphisms of Certain Genes in Patients with Abdominal Aortic Aneurysm
Authors: Kalmykov Egan , Suchkov Igor’  A. , Kalinin Roman E. , Ne’matzoda Okildyhon , Dodkhoev Jamshed S.
Published: December 2022

INTRODUCTION: To date, many factors that influence the risk and course of abdominal aortic aneurysm (AAA) are not studied. Increasing significance in the etiology and development of AAA is assigned to the existence of some genetic polymorphisms, the role of many of them is not studied either.
AIM: To analyze the existence of association of the abdominal aortic aneurysm with some gene polymorphisms (GPs).
MATERIALS AND METHODS: Gene polymorphisms were analyzed in 20 patients with AAA (study group, SG); 18 men (90%) and 2 women (10%), the mean age 68.1 7.3 years), and in 5 patients without AAA (control group, CG; 4 men (80%) and 1 woman (20%), the mean age 64.2 7.2 years). The frequency of concomitant diseases and risk factors for AAA were determined. The following GPs were studied: : Lys198Asn in the EDN1 gene; C-786T in the NOS3 gene; Leu28Pro in the APOE gene; Val174Ala in the SLC01B1 gene; Thr715Pro in the SELP gene; C807T in the ITGA2 gene; Ser447Ter in the LpL gene; Thr174Met in the AGT gene; Met235Thr in the AGT gene. Statistical analysis was performed using IBM SPSS Statistics 21, correlation analysis ― according to Pearson. The results were considered statistically significant at p 0.05.
RESULTS: In the SG, correlation relationships were identified in Ser447Ter polymorphism in the LpL gene: direct relationships with Lys198Asn polymorphism (r = 0.63; р 0.001) in the EDN1 gene, Leu28Pro (r = 0.70; р 0.001) in the APOE gene and Thr715Pro (r = 0.63; р 0.001) in the SELP gene; a reverse relationship with С786Т polymorphism (r = -0.35; р = 0.006) in the NOS3 gene. The same amount of relationships were found in Leu28Pro polymorphism in the APOE gene: besides with Ser447Ter in the LpL gene, there is also a direct relationship with Lys198Asn (r = 0.70; р 0.001) in the EDN1 gene and Thr715Pro (r = 0.63; р 0.001) in the SELP gene; a reverse relationship with С786Т (r = -0.35; р = 0.006) in the NOS3 gene. Thr715Pro polymorphism in the SELP gene, along with relationships with Ser447Ter (r = 0.63; р 0.001) in the LpL gene and Leu28Pro in the APOE gene, has an additional direct relationship with Lys198Asn (r = 0.55; р 0.001) in the EDN1 gene. Thr174Met polymorphism in the AGT gene has a reverse relationship with Leu28Pro (r = -0.35; р = 0.006) in the APOE gene and direct relationship with Val174Ala (r = 0.40; р = 0.002) in the SLC01B1 gene. With this, Met235Thr polymorphism in the AGT gene has a direct relationship with Val174Ala (r = 0.33; p = 0.011) in the SLC01B1 gene and reverse relationship with C807T in the ITGA2 gene.
CONCLUSION: The existence of direct correlations of some gene polymorphisms in patients with abdominal aortic aneurysm has been established, which indicates their probable role in the development of this pathology and may be used as a screening test for determination of the likelihood for its development.
Comparative Analysis of Personality-Related and Value-and-Meaning-Related Characteristics of Narcological Patients and Healthy Individuals (Abstainers) in Terms of Tertiary Prevention
Authors: Korduban Vladimir V. , Buzik Oleg Zh. , Agibalova Tat'yana V.
Published: December 2022

INTRODUCTION: Achievement of absolute sobriety, its maintenance and preservation are the main tasks of the stage of tertiary prophylaxis of narcological patients.
AIM: To perform a comparative analysis of personality- and value-and-meaning-related characteristics of narcological patients with syndrome of addiction to psychoactive substances, with similar characteristics of healthy individuals without significant experience in use of alcohol and other psychoactive substances (absolute and relative abstainers).
MATERIALS AND METHODS: The age, gender, level of education, experience in use of nicotine in the past and present, leading coping strategies, levels of religiosity and magic thinking have been studied.
RESULTS: Two diametrically opposite images of abstainers were identified: on the one end individuals with higher level of education and lower levels of religiosity and magic thinking, and on the other individuals with lower level of education, but higher levels of religiosity and magic thinking. The group of abstainers is in general characterized by absence of the experience in nicotine use.
CONCLUSION: Taking into account personality- and value-and-meaning-related characteristics helps more accurately determine the goals and directions of psychotherapeutic and rehabilitation measures, to differentiate patients according to rehabilitation programs, increases the level of motivation and adherence to treatment, which in turn leads to a longer and stable remission.
Protective Effects of L-Arginine on Mitochondria of Rat Epididymis in Hyperhomocysteinemia Induced by Prolonged Methionine Load
Authors: Zvyagina Valentina I. , Shumaev Konstantin B. , Belskikh Eduard S. , Uryasyev Oleg M. , Akhmedova Sabina R. , Marsyanova Yulia A. , Shitikova Anna M. , Suchkova Olga N.
Published: December 2022

INTRODUCTION: The study of markers of oxidative stress, metabolites of nitric oxide (II) (NOx) and the balance of carnitine fractions in mitochondria of rat epididymis, permits to evaluate the protective role of L-arginine in experimental hyperhomocysteinemia.
AIM: To study the influence of L-arginine on the parameters of energy metabolism, level of NO metabolites, oxidative modification of proteins and balance of carnitine fractions in mitochondria of the head and tail of rat epididymis in hyperhomocysteinemia.
MATERIALS AND METHODS: In animals of group 1 (n = 8), severe hyperhomocysteinemia (HHcy) was modeled by administration of methionine suspension at a dose of 1.5 g/kg twice daily for 21 days with addition of 1% methionine in drinking water; group 2 rats (n = 8) received suspension base without methionine; animals of group 3 (n = 8) were daily administered L-arginine solution at a dose of 500 mg/kg intragastrically against the background methionine load from day 11 to day 21; group 4 animals (n = 8) were administered L-arginine solution of at a dose of 500 mg/kg for 10 days; group 5 (n = 8) served as a control for group 4 and received drinking water intragastrically. Concentrations of total homocysteine and NOx were determined in serum. In the mitochondrial fraction of the homogenate of epididymis tissues, the level of oxidatively modified proteins (OMP), the concentration of NOx, lactate and carnitine fractions, the activity of lactate dehydrogenase (LDH), superoxide dismutase (SOD), H+-ATPase, succinate dehydrogenase (SDH) were evaluated.
RESULTS: HHcy was accompanied by reduction of the level of NOx in blood serum and mitochondria of epididymis head tissues. In mitochondria of tissues of head and tail of epididymis, a marked reduction of all fractions of carnitine, activity of LDH, H+-ATPase, SDH, increase in the activity of SOD and in the level of OMP were observed. With modeled HHcy, L-arginine reduced the extent of hyperhomocysteinemia, prevented reduction of NOx level in the blood serum and epididymis head and reduced the content of OMP of the epididymis mitochondria.
CONCLUSION: L-arginine introduced in combination with methionine, reduces the extent of severity of hyperhomocysteinemia. The positive effect of L-arginine on increase in the concentration of NOx metabolites in blood serum and mitochondria of epididymis in conditions of methionine load was also confirmed. L-arginine exhibits antioxidant properties, reducing the severity of oxidative stress induced by hyperhomocysteinemia. Differences in the adaptive response to oxidative stress of the mitochondria of the head and tail of epididymis were demonstrated.
Mathematical modeling of the rotor dynamics of a turbomachine on gas foil bearings subjected to vibration
Authors: Nikolaev Vitaly S. , Tishchenko Igor V.
Published: December 2022

BACKGROUND: The use of gas foil bearings is a promising development in the field of turbomachinery due to their economy, autonomous operation capability, and durability. However, gas foil bearings have lower load capacities than other types of bearings. However, turbomachines are complicated, dynamic systems that must meet high standards of safety, sustainability, and durability against external mechanical factors like vibration, shock, etc.
AIM: Development of a mathematical model of rotor dynamics to predict the displacement of the rotor in foil bearings for maintaining separation between the rotor and the housing while being subjected to vibration.
METHODS: A mathematical model of the dynamics of a stiff rotor on gas foil bearings was built and analyzed, taking into account the flexibility of the bearing bushing supports and the housing of the turbomachine. Stationary and transient modes of operation, including the transient modes combined with random vibration, are simulated. The system of ordinary derivatives equations describing the mathematical model was solved by the Rado IIA method. Random vibration was modeled using digital Fourier transformation. The modeling results were analyzed by discrete Fourier transformation and short-time Fourier transformation.
RESULTS AND CONCLUSIONS: Rotor movement trajectories were obtained and the results were compared with authors previous experimental data. Upper bound of maximal displacements was obtained. The maximum values of rotor displacement can be used to set the optimal values of blade tip gaps.
One-stage ventral correction of the secondary thoracolumbar kyphosis in a patient with failed transpedicular fixation of Th12 fracture
Authors: Ostrovskij Vladimir V. , Shulga Alexey E. , Zaretskov Vladimir V. , Bazhanov Sergey P. , Likhachov Sergey V. , Smolkin Alexey A.
Published: December 2022

The main surgical treatment technique of thoracic and lumbar spine acute injuries is transpedicular fixation, the failure of which, according to the literature data, occurs in 1015% of cases. There are no common views on tactics and the surgical technique used to deal with the consequences of unstable transpedicular spondylosynthesis. And the publications devoted to the use of isolated anterior interventions are the least common.
We present a case study of the surgical management of the 71 years old patient with secondary thoracolumbar kyphosis that progressed after failed transpedicular fixation of Th12 fracture. The deformity was corrected with one-stage anterior approach and ventral crew system.
OPTIMIZATION OF CHROMIUM AND LEAD BIOSORPTION IN WASTEWATER USING 33 FACTORIAL DESIGN
Authors: YAZICI Berna , MALKOÇ Semra , ÖZGÖREN Ece , DURSUN Nur
Published: December 2022

In this study removing heavy metals, Cr (III), and Pb (II) from wastewater, Microorganism Trichoderma sp. biosorption was performed using Cr (III), and Pb (II) removal was taken into account. For this study, 3^3 Factorial Experiment Designs were used, and temperature (°C), biosorbent dosage (g/L), and pH were selected as the main factors for Cr (III), and Pb (II) metals and three levels of these factors were determined as low, medium, and high. In this study, which was carried out to increase the metal removal efficiency and biosorption capacity, the main factors and the significance of each interaction of these factors were examined with 3^3 Factorial Design. For this purpose, by conducting Analysis of Variance (ANOVA) via Response Surface Methodology and optimization, more detailed results were obtained regarding the factors affecting the efficiency of metal removal from wastewater.
La independencia judicial en la jurisprudencia del Tribunal de Justicia de la Unión Europea
Authors: Sarmiento Ramírez-Escudero Daniel , Arnaldos Orts Enrique
Published: December 2022

El presente trabajo tiene por objeto analizar el concepto de independencia judicial en la jurisprudencia del Tribunal de Justicia de la Unión Europea, acudiendo, en primer lugar, a una definición general y considerando su anatomía a partir de sus dos manifestaciones principales: su condición de cualidad necesaria los órganos jurisdiccionales para ser considerados como tales en el contexto de la remisión prejudicial y su carácter de condición sine qua non del Estado de derecho. Igualmente, se hacen unas consideraciones sobre las consecuencias de su configuración para el propio ordenamiento jurídico de la Unión así como respecto de su interacción con otros estándares de independencia judicial que dialogan con el comunitario.
The effect of nitrogen, magnesium and iron applications on the nutrient content of parsley
(Petroselinum crispum)
Authors: Yağmur Bulent , Okur Bulnet , Okur Nur
Published: December 2022

The aim of this study is to investigate the effects of different rates of N, Mg and Fe applications on the mineral content of parsley leaves. The experiment was carried out in a greenhouse according to the randomized plot design with three replications. Seven N, Mg and Fe dose treatments were designed as 130, 160, 190, 220, 250, 280 and 310 kg per ha N as ammonium nitrate (33% N), 40, 80, 120, 160, 200, 240 and 280 kg per ha Mg as magnesium sulphate (16% MgO) and 8, 16, 24, 32, 40, 48 and 56 Fe kg per ha as ferrous sulphate (20% Fe). The treatments did not significantly affect phosphorus concentrations in parsley leaves. The nitrogen uptake of the plant increased in all three element applications and the highest N, K and Ca values were determined in nitrogen fertilizer applications. The nitrate amount in the leaves also increased depending on the increasing N rates. The results indicate that the most effective fertilizer in the nutrition of parsley is nitrogen fertilizers and nitrogen doses up to 310 kg per ha did not increase the nitrate amount in parsley above the permissible level.
Štetnost kukuruzne zlatice (Diabrotica virgifera virgifera LeConte) u uvjetima
Authors: Lović Ivan , Sarajlić Ankica , Raspudić Emilija
Published: December 2022

Kukuruzna zlatica (Diabrotica virgifera virgifera LeConte) pripada najvažnijim štetnicima kukuruza. Istraživanje je provedeno u Gorjanima tijekom 2020. godine s ciljem utvrđivanja kako ponovljena sjetva kukuruza utječe na pojavu i brojnost kukuruzne zlatice, razinu oštećenja korijena, tolerantnost biljaka te prinos. Zasijan je hibrid kukuruza OS 378 u dva tretmana (ponovljena sjetva i monokultura tri godine). Štete uzrokovane hranidbom ličinaka utvrđene su očitanjem oštećenja korijena. Tolerantnost biljaka utvrđena je očitanjem veličine korijena i razvoja sekundarnoga korijenja, a let imaga pratio se žutim ljepljivim pločama. Prisutnost kukuruzne zlatice zabilježena je na objema istraživanim parcelama. Prosječna brojnost imaga po danu i mamcu u ponovljenoj sjetvi iznosila je 1,07, a u trogodišnjoj monokulturi 0,99. Oštećenje korijena ocijenjeno je prosječnom ocjenom 0,75 (ponovljena sjetva), odnosno 1,25 (trogodišnja monokultura). Veličina korijena ocijenjena je prosječnim ocjenama 2,50 (ponovljena sjetva) i 3,70 (trogodišnja monokultura), a prosječni porast sekundarnoga korijenja s 3,20 (ponovljena sjetva), odnosno 3,05 (trogodišnja monokultura). Lošije ocjene korijena bile su kod uzgoja kukuruza u trogodišnjoj monokulturi, što ukazuje kako dodatna godina monokulture može uzrokovati veće štete. Prinos kukuruza u ponovljenoj sjetvi bio je viši za 2,53 t/ha u odnosu na trogodišnju monokulturu. Preporuča se izbjegavanje daljnje sjetve kukuruza na ovim površinama te poštivanje višegodišnjega plodoreda.
Marconi Wireless Telegraphy Trialled in Australia
Authors: Moorhead Simon
Published: December 2022

A historic paper from 2010, republished here, describes a demonstration of wireless transmission between Victoria and Tasmania by the Marconi Wireless Telegraph Company in 1906. The subsequent debate and delays in adopting the new wireless communication system highlight the influence of imperial politics on Australian telecommunications, post Federation. The impasse with Marconi over his initial refusal to license his patent was eventually resolved by the creation of Amalgamated Wireless Holdings (AWA) in 1911.
Test-retest reliability of the computerized rotational head impulse test in the pediatric population
Authors: Mittendorf Nicole , Reddy Tarryn Marisca , Heinze Barbara , Kiderman Alex , González Jorge
Published: December 2022

Background: This study aimed to determine the test-retest reliability of the computerized rotational head impulse test (crHIT) as an additional clinical tool to assess horizontal semi-circular canal (HSCC) function in pediatric population.

Methods: To determine the test re-test reliability of the crHIT, the study included 29 normally developing children with a mean age of 12.2 years±2.7 (range: 8-17 years) with no history of vestibular symptoms and disorders. Participants underwent two crHITs within one session and one crHIT in the following session. Each crHIT included one protocol using an earth fixed target. The test-retest reliability was determined using a quantitative research approach with a repeated measures design.

Results: Mean angular vestibulo-ocular reflex (aVOR) gain of 1.01 (session 1), 1.00 (session 2), and 1.01 (session 3) were obtained. Regression analysis revealed no significant difference for leftward rotations within-session (p=0.608) and between-session (p=0.318) for the differences measured. The same was seen for rightward rotations revealing no significant difference within-session (p=0.631) and between-session (p=0.523).

Conclusions: The crHIT is a reliable clinical tool in assessing HSCC functioning in the pediatric population as it demonstrates good test-retest repeatability. The crHIT is a valuable complementary assessment to the video head impulse test (vHIT), since it is well tolerated by children, it is simple to administer and head velocities of >100°/sec are easily attainable. Extending the pediatric vestibular test battery with crHIT can be a valuable diagnostic tool without adding to the overall test time.

 
ART AND SCULPTURE PATTERNS IN CREATING STAGE IMAGES BY ANNA PAVLOVA
Authors: Portnova Таtiana
Published: December 2022

This article is a comprehensive analysis of the development of Anna Pavlova’s creative art in a manner which enables translation of her physical stage roles into production of models and sculptures. The author considers formation and evolution of her creative style: individual performer’s artistic style, choreography manner and type or direction in Russian ballet schools, reflecting the system of thought of the nineteenth and twentieth centuries. Pavlova’s stage roles, not previously reflected in the literature, have been analyzed, a comprehensive scientific assessment and systematic review of choreographic images have been given in relation to figurative interpretation of the main character of the performance, wherein she acted as the artist-dancer-creator
A case report of multiple supernumerary teeth: Post-permanant dentiton or hyperactivity of dental lamina
Authors: Srikanth T  , Sumalatha CH  , Sankeerti Mala B  , Srikanth E  , Gowtham P
Published: December 2022

Supplementary teeth in simple terms could be be defined as those supernumerary teeth which are well aligned in the arch resembling the normal anatomical structures of teeth. There has been evidences of supplementary premolars and molars since from beginning of the civilization. According to Darwin’s theory of evolution which stated that during the course of humans evolution the organs which do not have greater use in regular became vestigial which included the appendix, tail bone, fourth molar. Supernumerary teeth often remain asymptomatic, and only get diagnosed incidentally during a routine dental visit on radiographs. Nevertheless, various complications have been reported in literature related to supernumerary teeth such as disturbed eruption, malpositioning or rotation, root resorption of neighbouring teeth, and development of dentigerous cysts in impacted supernumeraries. Root resorption of neighbouring teeth can be radiographically diagnosed in up to 22.8% of the cases. Here we report an unusual case of multiple supernumerary teeth in a non-syndromic patient of African native.
A review on COVID-19, colonising microflora and microbial links to age-related differences and off-target effect of live vaccines like BCG
Authors: Sangeetha Vani G , Swapna M
Published: December 2022

Age-related expression for a disease is well known. The applicability of such an expression for SARS-CoV-2 prompted this review. Whenever an infection is highly prevalent, the younger age groups get more affected. But this is not seen in COVID-19. The severity of COVID-19 disease is more and sometimes fatal in adults when compared with children and found to be less severe. This shows a striking difference as generally children tend to get more affected with most of the respiratory viruses.

Can this be explained by the differences that are observed in their oro-pharyngeal, lung, nasopharyngeal and gastrointestinal microbiota? This review addresses the potential of resident microbiota for the spectrum of expressions in susceptible population through various mechanisms. In the nasopharynx, where microbial interactions and competition may limit the growth of SARS-CoV-2, children are more extensively colonized with viruses and bacteria than adults. One study found no discernible differences in the nasopharyngeal microbiota between SARS-CoV-2 patients and healthy individuals, whereas other investigations found significant differences in the oro-pharyngeal, lung and gut microbiota between these groups.

There is a reduced load of bacteria in the gut microbiota of the patients who are infected with COVID-19; especially the bacterial phyla such as are found to be very less in the gut but there is relatively a higher load of other organisms such as It is known that have a lot of anti-inflammatory properties and show decreased gastrointestinal ACE-2 expression. The microbiota in the human gastrointestinal tract differs with age. Children’s guts exhibit higher concentrations of These variations in the gut microbiota of patients have also been noted between those who do and those who don’t excrete SARS-CoV-2 in their feces. However, these results, which are based on the gut flora of each patient, may be affected by factors like food, age, use of antibiotics and their immune system. This relation between the gut microbiota and the severity of COVID-19 disease in patients is studied and it is still unclear. Randomized control trials (RCT) of BCG are being conducted to lessen the severity of COVID-19. Oral polio vaccination and the measles-containing vaccine (MCV), in addition to BCG, have been proposed as potential factors in the difference in COVID-19 severity. To lessen the severity of COVID-19, a randomized control trial of the MMR vaccine has been planned. Understanding the mechanism underlying the age-related variations in COVID-19 severity through the colonizing microbial flora and off-target effects of live vaccines (BCG, etc.) would provide important cognizance and open up many opportunities for the management and cure of this novel infection.
A case report: Nocardia otitidiscaviarum bacteraemia in a patient with metastatic lung adenocarcinoma
Authors: Shah Sweta , Thakkar Pooja , Goyle Sandeep , Jadhav Shweta
Published: December 2022

A 73 years old male patient, was admitted with fever, cough and generalised weakness since two to three days. He was diagnosed to have metastatic adenocarcinoma of lung 3 months back and was on chemotherapy. His blood culture grew The patient succumbed to the disease and various other comorbidities that had led to multi-organ failure. Incidence of bacteraemia due to nocardia and the associated common species in India is not known yet. It is imperative to widen the scope of the laboratory and to use diverse laboratory tools for accurate and rapid diagnosis of rare and unconventional pathogens.