bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of genetic factors in the development of thrombosis in cancer patients
Authors: Özkan M. , Koçyigit I. , Dikilitas M. , Özkul Y. , Sari I. , Karaca H. , Emirogullari F. , Eser B. , Er O. , Unal A.
Published: August 2020

e22227

Background: Thromboembolism is frequent in patients with cancer. Although it is known that several acquired factors take place in this process, the role of the genetic factors is controversial. In this study we analysed the most common genetic polymorphisms which have a role in the development of thrombosis. Methods: Study population consists of 292 (158 with thrombosis and 134 without thrombosis) patients treated between 2004 and 2008. Thrombosis was diagnosed by clinically and radiological measures in any time during the course of disease. Factor V Leiden G1691A, Prothrombin G20210A, Methlene Tetra Hydrofolate Reductase (MTHFR) C677T and Plazminogen Activator Inhibitor (PAI-1) 4G/5G were analysed with PCR-RFLP (Polymerase Chain Reaction- Restriction Fragment Length Polymorphism). Results: In the study group 48 and 1 patient had heterozygot and homozygot polymorphism for Factor V Leiden G1691A respectively. In the control group 32 heterozygot and 1 homozygot polymorphism and there was no statistically significant differents between study and control group (p=0,462).For Protrombin G20210A 11 and 4 heterozygot polymorphism were observed in control and study group respectively. While there was 1 homozygot polymorphism in study group there was no in control group and the difference between two groups was not statistically significant (p=0,198). For MTHFR C677T, 48 and 24 heterozygot polymorphism, 15 and 12 homozygot polymorphism were observed in study and control group respectively. The difference between two groups were statistically significant (p=0,04). There was no statistically significant difference between two groups for PAI-1 4G/5G polymorphisms (p=0,362). In subgroup analyses, statistically significant difference was found only in MTHFR C677T polymorphism in patients with GI cancer and with and without thrombosis (p=0,028). Conclusions: The studies investigating the relationship between genetic factors and thrombosis revealed controversial results. However, we found no genetic factor relevant to thrombosis other than MTHFR C677T polymorphism. Further studies investigating genetic and acquired factors in the development of the thrombosis in detail are warranted for documenting clearly the role of genetic polymorphisms.

No significant financial relationships to disclose.
Identification and characterization of SP cells in human lung adenocarcinoma SPC-A1 cells
Authors: Zhu Y. , Chen L.
Published: August 2020

e22230

Background: There has been an increasing interest in recent years in the role stem cells play in health and disease. With an extensive understanding of their biology, a major role for stem cells in the malignant process has been proposed and the existence of cancer stem cells(CSCs) has been confirmed in hematopoietic malignancies, brain cancer, and solid organ malignancies including breast, prostate, colon, and pancreatic cancer. Lung cancer is the leading cause of cancer mortality in most large cities of China. It is possible that lung cancer contains cancer stem cells responsible for its malignancy. The aim of this study is to identify, characterize and enrich the CSC population that drives and maintains lung adenocarcinoma growth and metastasis. Methods: Side population (SP) cell analysis and sorting were applied to established human lung adenocarcinoma cell line and an attempt to further enrich them by preliminary serum-free culture before fluorescence activated cell sorting(FACS) was done. Stem cell properties of SP cells were evaluated by their proliferative index, colony-forming efficiency, tumorigenic potential, bi-differentiation capacity and the expression of common stem cell surface markers. Results: Lung cancer cells could grow in a serum-free Medium (SFM) as non-adherent spheres similar to neurospheres or mammospheres. The proportion of SP cells in cell spheres was significantly higher than that in cells grown as monolayers. SP cells had a greater proliferative index, a higher colony-forming efficiency and a greater ability to form tumor in vivo. SP cells were both CCA positive and SP-C positive while non-SP cells were only SP-C positive. Flow cytometric analysis of cell phenotyping showed that SP cells expressed CD133 and CD44, the common cell surface markers of cancer stem cells, while non-SP cells only expressed CD44. Conclusions: SP cells existed in human lung adenocarcinoma cell lines and they could be further enriched by preliminary serum-free culture before FACS sorting. SP cells possessed the properties of cancer stem cells.

No significant financial relationships to disclose.
Low frequency of RAS and absence of FLT3-ITD gene mutations in patients with Myelodysplastic Syndromes in India: AIIMS experience
Authors: Chaubey R. , Sazawal S. , Mahapatra M. , Saxena R.
Published: August 2020

e22231

Background: Chromosomal abnormalities and molecular detection has potential importance for diagnosis and prognosis of MDS, although the mechanisms underlying the development of MDS and their progressive evolution to AML are still largely unknown. Since, no studies have been reported from India on the prevalence of N-RAS, K- RAS point mutation in codon 12 and FLT3-ITD mutations in patients with MDS, we undertook this study. Methods: DNA and RNA were extracted from bone marrow /peripheral blood. Using RT-PCR the patients were screened for length mutations in FLT3 gene. PCR-RFLP and nested PCR-RFLP were used for the detection of point mutation in codon 12 of N-RAS and K-RAS. Results: A total of 53 patients (median age 39 yrs, range 9–78yrs; M: F 2:1; median TLC-3.9×109/l, range 0.8–116 ×109/l Median platelet count- 87 ×109/l, range 1–349 ×109/l, Median hemoglobin -6.8 g/dl, range 2.7- 16.1 g/dl, were studied. One out of 53 patients (2%) was found positive for N-RAS and four patients were positive for K-RAS (8%) mutation. FLT3-ITD mutation was studied in 47 patients; all the patients were found negative. The mean observation of all the patients was 30 months and the median overall survival was 28 months. Nine patients died during follow up. The presence of N-RAS codon 12 mutation was associated with the poor survival. FLT3-ITD mutation was not observed in any of our cases, which is in contrast to 3% reported from the West. Conclusions: Thus, it appears that the RAS and FLT3 mutations are uncommon in MDS patients in India.

No significant financial relationships to disclose.
HER2 status testing by immunohistochemical and fFluorescence in situ hybridization in China
Authors: Tao W. , Zefei J. , Xuan Z. , Xiaobing L. , Shaohua Z. , Ge S. , Min Z. , Shikai W. , Santai S.
Published: August 2020

e22233

Background: HER2 gene overexpression is associated with aggressive breast cancer and poor clinical prognosis. Humanized anti-HER2 monoclonal antibody trastuzumab, which is targeted HER2 protein has showed to improve overall survival in patients with HER2-positive breast cancer in both the metastatic and adjuvant settings. There are some differences in HER2 positive rate among difference reports in China. This study tested HER2 status by immunohistochemistry(IHC) and fluorescence in situ hybridization (FISH) and compared HER2 testing at central and regional laboratories in China. Methods: Assessment of HER2 status was performed by FISH using the HercepTeast kit at central laboratory and by IHC using commercial available anti-HER2 probe in formalin-fixed and paraffin-embedded tissue section of 280 breast cancer samples. IHC HER2 testing was performed on 149 samples in the central laboratory. IHC HER2 testing was performed on 80 samples at both central laboratory and regional laboratory. Results: 280 samples were tested 373 times testing by IHC and FISH. The results were showed in table 1 . 80 samples was tested by IHC at central and regional laboratory and testing results of 36.4% samples were accordant (K=0.038). 94.1% IHC3+ at central laboratory were HER2 FISH positive and 83.3% IHC 3+ at regional laboratory were HER2 FISH positive. 86.7% IHC 2+ at central laboratory were HER2 FISH positive and 62.7% IHC 2+ at regional laboratory were HER2 FISH positive. 17 samples were observed HER2 FISH positive in the 27 IHC 0/1+ tested at regional laboratoty. So good correlation was obsearved between FISH HER2 status and IHC results from central laboratory but not from regional laboratory. Conclusions: This study emphasized the important of accurate HER2 testing. HER2 FISH test should be performed for the IHC 2+ samples. Even HER2 FISH test maybe performed for IHC 0/1 sample according to clinical characteristics in China in order to make the patients have targeted therapy chance.

[Table: see text]

No significant financial relationships to disclose.
Efficacy results from the ToGA trial: A phase III study of trastuzumab added to standard chemotherapy (CT) in first-line human epidermal growth factor receptor 2 (HER2)-positive advanced gastric cancer (GC)
Authors: Van Cutsem E. , Kang Y. , Chung H. , Sawaki A. , Lordick F. , Hill J. , Lehle M. , Feyereislova A. , Bang Y.
Published: August 2020

LBA4509

The full, final text of this abstract will be available in Part II of the 2009 ASCO Annual Meeting Proceedings, distributed onsite at the Meeting on May 30, 2009, and as a supplement to the June 20, 2009, issue of the Journal of Clinical Oncology.

[Table: see text]
Breast cancer molecular profiles and tumor response of neoadjuvant doxorubicin and paclitaxel: The I-SPY TRIAL (CALGB 150007/150012, ACRIN 6657)
Authors: Esserman L. J. , Perou C. , Cheang M. , DeMichele A. , Carey L. , van 't Veer L. J. , Gray J. , Petricoin E. , Conway K. , Berry D.
Published: August 2020

LBA515

The full, final text of this abstract will be available in Part II of the 2009 ASCO Annual Meeting Proceedings, distributed onsite at the Meeting on May 30, 2009, and as a supplement to the June 20, 2009, issue of the Journal of Clinical Oncology.

[Table: see text]
A randomized, phase III study of carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in relapsed platinum-sensitive ovarian cancer (OC): CALYPSO study of the Gynecologic Cancer Intergroup (GCIG)
Authors: Pujade-Lauraine E. , Mahner S. , Kaern J. , Gebski V. , Heywood M. , Vasey P. , Reinthaller A. , Vergote I. , Pignata S. , Ferrero A.
Published: August 2020

LBA5509

The full, final text of this abstract will be available in Part II of the 2009 ASCO Annual Meeting Proceedings, distributed onsite at the Meeting on May 30, 2009, and as a supplement to the June 20, 2009, issue of the Journal of Clinical Oncology.

No significant financial relationships to disclose.
A randomized, phase III study (AGO-OVAR-9, GINECO-TCG, NSGO-OC-0102): Gemcitabine-paclitaxel-carboplatin versus paclitaxel-carboplatin as first-line treatment of ovarian cancer (OC): Survival of FIGO stage I-IIA patients
Authors: Herrstedt J. , Huober J. , Priou F. , Müller H. , Baekelandt M. , Kurzeder C. , Pfisterer J. , Stähle A. , Ray-Coquard I. , du Bois A.
Published: August 2020

LBA5510

The full, final text of this abstract will be available in Part II of the 2009 ASCO Annual Meeting Proceedings, distributed onsite at the Meeting on May 30, 2009, and as a supplement to the June 20, 2009, issue of the Journal of Clinical Oncology.

[Table: see text]
Longitudinal Changes in Hematologic Parameters Among Transgender People Receiving Hormone Therapy
Authors: Antun Ana , Zhang Qi , Bhasin Shalender , Bradlyn Andrew , Flanders W Dana , Getahun Darios , Lash Timothy L , Nash Rebecca , Roblin Douglas , Silverberg Michael J , Tangpricha Vin , Vupputuri Suma , Goodman Michael
Published: August 2020

Context

The effect of gender-affirming hormone therapy (HT) on erythropoiesis is an area of priority in transgender health research.

Objective

To compare changes in hematologic parameters and rates of erythrocytosis and anemia among transgender people to those of cisgender controls.

Design

Longitudinal observational study.

Participants and Setting

We compared 559 transfeminine (TF) and 424 transmasculine (TM) people enrolled in 3 integrated health care systems to matched cisgender referents.

Interventions and Outcome

Hormone therapy receipt was ascertained from filled prescriptions. Hemoglobin (Hb) and hematocrit (Hct) levels were examined from the first blood test to HT initiation, and from the start of HT to the most recent blood test. Rates of erythrocytosis and anemia in transgender participants and referents were compared by calculating adjusted hazard ratios and 95% confidence intervals (CI).

Results

In the TF group, there was a downward trend for both Hb and Hct. The corresponding changes in the TM cohort were in the opposite direction. TM study participants experienced a 7-fold higher rate (95% CI: 4.1–13.4) of erythrocytosis relative to matched cisgender males, and an 83-fold higher rate (95% CI: 36.1–191.2) compared to cisgender females. The corresponding rates for anemia were elevated in TF subjects but primarily relative to cisgender males (hazard ratio 5.9; 95% CI: 4.6–7.5).

Conclusions

Our results support previous recommendations that hematological parameters of transgender people receiving HT should be interpreted based on their affirmed gender, rather than their sex documented at birth. The clinical significance of erythrocytosis following testosterone therapy, as well as anemia following feminizing HT, requires further investigation.
Metabolomic Profiling After a Meal Shows Greater Changes and Lower Metabolic Flexibility in Cardiometabolic Diseases
Authors: Yu Elaine A , Yu Tianwei , Jones Dean P , Ramirez-Zea Manuel , Stein Aryeh D
Published: August 2020

Context

Metabolic flexibility is the physiologic acclimatization to differing energy availability and requirement states. Effectively maintaining metabolic flexibility remains challenging, particularly since metabolic dysregulations in meal consumption during cardiometabolic disease (CMD) pathophysiology are incompletely understood.

Objective

We compared metabolic flexibility following consumption of a standardized meal challenge among adults with or without CMDs.

Design, Setting, and Participants

Study participants (n = 349; age 37-54 years, 55% female) received a standardized meal challenge (520 kcal, 67.4 g carbohydrates, 24.3 g fat, 8.0 g protein; 259 mL). Blood samples were collected at baseline and 2 hours postchallenge. Plasma samples were assayed by high-resolution, nontargeted metabolomics with dual-column liquid chromatography and ultrahigh-resolution mass spectrometry. Metabolome-wide associations between features and meal challenge timepoint were assessed in multivariable linear regression models.

Results

Sixty-five percent of participants had ≥1 of 4 CMDs: 33% were obese, 6% had diabetes, 39% had hypertension, and 50% had metabolic syndrome. Log2-normalized ratios of feature peak areas (postprandial:fasting) clustered separately among participants with versus without any CMDs. Among participants with CMDs, the meal challenge altered 1756 feature peak areas (1063 reversed-phase [C18], 693 hydrophilic interaction liquid chromatography [HILIC]; all q < 0.05). In individuals without CMDs, the meal challenge changed 1383 feature peak areas (875 C18; 508 HILIC; all q < 0.05). There were 108 features (60 C18; 48 HILIC) that differed by the meal challenge and CMD status, including dipeptides, carnitines, glycerophospholipids, and a bile acid metabolite (all P < 0.05).

Conclusions

Among adults with CMDs, more metabolomic features differed after a meal challenge, which reflected lower metabolic flexibility relative to individuals without CMDs.
Ambulance Emergency Response Optimization in Developing Countries
Authors: Boutilier Justin J. , Chan Timothy C. Y.
Published: August 2020

Improving Ambulance Response Times in Developing Urban Centers
The impact of COVID-19 on residents, relatives and staff in care homes
Authors: Ashurst Adrian
Published: August 2020

We are now only beginning to realise the long-term implications of living alongside COVID-19. Adrian Ashurst investigates the impact of social distancing guidelines and restricted visitation
Difficult conversations: nutritional needs of care home residents with advanced dementia
Authors: Aldridge Zena , Parry-Hughes Maggie , Dening Karen Harrison
Published: August 2020

The decline of a person with dementia can be unpredictable, and decisions regarding nutrition and dietary needs can be a particular area of concern. Zena Aldridge, Maggie Parry-Hughes and Karen Harrison Dening discuss some of the challenges associated with the provision of appropriate nutritional support for people with advanced dementia
Moore-Penrose inverse of some linear maps on infinite-dimensional vector spaces
Authors: Pablos Romo Fernando , Cabezas Sánchez Víctor
Published: August 2020

The aim of this work is to characterize linear maps of infinite-dimensional inner product spaces where the Moore-Penrose inverse exists. This MP inverse generalizes the well-known Moore-Penrose inverse of a matrix $A\in \text{Mat}_{n\times m} ({\mathbb C})$. Moreover, a method for the computation of the MP inverse of some endomorphisms on infinite-dimensional vector spaces is given. As an application, the least norm solution of an infinite linear system from the Moore-Penrose inverse offered is studied.
Optimization of noncollinear AOTF design for laser beam shaping
Authors: Yushkov Konstantin B. , Chizhikov Alexander I. , Makarov Oleg Yu. , Molchanov Vladimir Ya.
Published: August 2020

Optimization of a wide-angle paratellurite acousto-optic tunable filter (AOTF) is performed for applications in laser beam shaping systems. The AOTF configuration with annular transfer function is analyzed. It is demonstrated that the optimal AOTF design for single-frequency operation as a narrow-band spatial frequency filter is obtained at acoustic propagation angle of 5.6° relative to the [110] axis. The optimal design for maximization of AOTF resolution in multifrequency laser beam shaping operation mode is obtained at acoustic propagation angle of 13.8°.
Autocorrected preconditioning regularization inversion algorithm for an atmospheric turbulence profile
Authors: Cheng Zhi , He Lixin , Zhang Xin , Mu Chao , Tan Ming
Published: August 2020

Atmospheric turbulence profiles have great significance for adaptive optics, astronomical observations, laser propagation in atmospheres, and free space optical communications. The two-aperture differential scintillation method is a recent approach for analyzing remote-sensing atmospheric turbulence profiles that utilizes active beacons to make it suitable for different measurement situations. The relationship between differential scintillation and atmospheric turbulence profiles can be modeled using the Fredholm integral equation. To address this ill-posed integration problem, the discrete forward observation equation is first analyzed to obtain better integration intervals and measurement intervals needed for inversion. Then an autocorrected preconditioning conjugate gradient normal residual (PCGNR) algorithm is proposed to acquire atmospheric turbulence profiles. The algorithm contains a developed autocorrection strategy that incorporates incremental differences, adaptive thresholds, and weighted averages to correct for artefacts and marginal errors that arise from the PCGNR method. Compared with other regularized methods, the proposed autocorrected PCGNR method is more accurate and robust in the presence of noise.
Single graphene derivative layer as a hole transport in organic solar
cells based on PBDB-T:ITIC
Authors: Amargós-Reyes Olivia , Caballero-Quintana Irving , Maldonado José-Luis , Nicasio-Collazo Juan , Romero-Borja Daniel
Published: August 2020

A layer of fluorinated reduced graphene oxide (FrGO), as an alternative
hole transport (HTL) in organic solar cells (OSCs) based on a
PBDB-T:ITIC active layer, is reported. OSC configuration is
ITO/HTL/PBDB-T:ITIC/PFN/FM; FM is Field’s metal, a
eutectic alloy deposited at room atmosphere. PEDOT:PSS,
FrGO/PEDOT:PSS, and FrGO are tested as HTLs; the average efficiencies
of 8.8, 8.2, and 5.3%, respectively, are reached. Inhomogeneity of the
FrGO layer is determined as the main factor that affects the
photovoltaic behavior and stability. Device stability is very
acceptable, sometimes with a superior behavior than data previously
reported; FM also could potentially contribute to this enhanced
stability.
SOFISM: Super-resolution optical fluctuation image scanning microscopy
Authors: Sroda Aleksandra , Makowski Adrian , Tenne Ron , Rossman Uri , Lubin Gur , Oron Dan , Lapkiewicz Radek
Published: August 2020

Super-resolution optical microscopy is a rapidly evolving scientific field dedicated to imaging sub-wavelength-sized objects, leaving its mark in multiple branches of biology and technology. While several super-resolution optical microscopy methods have become a common tool in life science imaging, new methods, supported by cutting-edge technology, continue to emerge. One rather recent addition to the super-resolution toolbox, image scanning microscopy (ISM), achieves up to twofold lateral resolution enhancement in a robust and straightforward manner. To further enhance ISM’s resolution in all three dimensions, we present and experimentally demonstrate here super-resolution optical fluctuation ISM (SOFISM). Measuring the fluorescence fluctuation contrast in an ISM architecture, we obtain images with a

×
2.5

lateral resolution beyond the diffraction limit along with an enhanced axial resolution for a fixed cell sample labeled with commercially available quantum dots. The inherent temporal averaging of the ISM technique enables image acquisition of the fluctuation correlation contrast within millisecond-scale pixel dwell times. SOFISM can therefore offer a robust path to achieve high-resolution images within a slightly modified confocal microscope, using standard fluorescent labels and reasonable acquisition times.
You need a thick skin in this game: Journalists’ attitudes to resilience training as a strategy for combatting online violence
Authors: Martin Fiona R. , Murrell Colleen
Published: August 2020

In recent years, resilience training has been recommended as a way to protect news workers from the impact of reporting on traumatic events. However, do journalists see it as a useful tool in dealing with online abuse and harassment? This article explores Australian journalists’ conceptions of resilience training, via a thematic analysis of interviews, and their concerns about its effectiveness in addressing digital violence. The study adopts an ethics of care framework for understanding the uses of resilience training in journalism education for increasing dialogic interaction with audiences. It finds that while some journalists understand resilience training’s relationship to positive mental health, the majority are not clear about its potential and how it might be taught. Our analysis also reveals normative beliefs about journalists’ need to develop ‘a thick skin’ against interpersonal and coordinated violence online. Overall, the article raises questions about how journalists might be better oriented to not only self-care but also collective care.
Worlds of Journalism: Journalistic Cultures Around the Globe, Thomas Hanitzsch, Folker Hanusch, Jyotika Ramaprasad and Arnold S. de Beer (eds) (2019)
Authors: Bebawi Saba
Published: August 2020

Review of: Worlds of Journalism: Journalistic Cultures Around the Globe, Thomas Hanitzsch, Folker Hanusch, Jyotika Ramaprasad and Arnold S. de Beer (eds) (2019)

New York: Columbia University Press, 448 pp.,

ISBN 978-0-23118-643-8, p/bk, $35.00,

ISBN 978-0-23118-642-1, h/bk, $105.00,

ISBN 978-0-23154-663-8, e/bk, $34.99
The Future Foreign Correspondent, Saba Bebawi and Mark Evans (2019)
Authors: Greste Peter
Published: August 2020

Review of: The Future Foreign Correspondent, Saba Bebawi and Mark Evans (2019)

Sydney: Palgrave Macmillan, 120 pp.,

ISBN 978-3-03001-667-8, h/bk, €49.99,

ISBN 978-3-03001-668-5, e/bk, €42.79
Practice, performance and the archive: Cases from Indian classical music genres
Authors: Deo Aditi , Subramanian Lakshmi
Published: August 2020

Given their emphasis on oral pedagogy and improvisatory approaches, Indian classical music genres present a challenge for constructing historically nuanced studies of musical practices, shifts in them over time and their links to broader developments. Much scholarship on Indian classical music tends to maintain loyalties to disciplinary silos such as social and cultural history, cultural studies and ethnomusicology, often sacrificing aspects of the spectrum of musical experiences. The dispersed nature of musical networks has meant that the archive for studying the phenomena of listening to, learning and disseminating music is fragmented, mobile and multi-local, not easy to capture with conventional methodologies of historical reconstruction or even purely ethnographic fieldwork. A central concern that drives the articles in this issue is a focus on exploring musical sound, repertoire and practices as archives. Such a focus raises two kinds of challenges. One is the identification of archives that can capture the ephemerality and immediacy of these musical practices; the other is the question of interpretive methods that can faithfully reflect the aesthetic and affective dimensions of musical practice. The contributors to this Special Issue explore a range of historical records centred on music – notations, compilations, repertoires, biographies, texts, anecdotes, performances, recordings, pedagogic tools – as their primary archives. Drawing upon disciplinary insights from cultural history, ethnomusicology and sound studies, and often in conversation with musicians and listeners, they offer conceptual and methodological lenses for reading such archives productively.
Technological conversations with the past: Musicians, connoisseurs and the audio archive of Hindustani khayal music
Authors: Deo Aditi
Published: August 2020

This article draws upon ethnographic interviews with musicians and archivists to unpack the symbolic, material and pedagogic modes through which contemporary listeners engage with khayal recordings of the past. Even as khayal thrives as a contemporary field of performance, the genre is associated deeply with notions of tradition and heritage. In this context, practitioners and connoisseurs consider twentieth-century master-musicians as frequent points of reference, and their recordings as authoritative expositions of the genre. Accumulated since the beginning of the twentieth century when sound technologies arrived in India, these recordings constitute the audio archive for the genre of khayal. The last two decades have seen attention towards making it accessible to interested audiences, primarily through the affordances of digital technologies. The article addresses questions such as: in what ways are past recordings translated and absorbed as part of khayal’s present? What are the implications of changes in technologies, sonic expectations and musical trends over the past several decades for such translations? And, more broadly, how do recorded sounds that have traversed technological and musical changes participate in the configuration of tradition as a contemporary phenomenon?
In conversation
Authors: Vaidyanathan Rama , Viswanath Kaladharan
Published: August 2020

Rama Vaidyanathan is a leading exponent of Bharatanatyam, a popular classical dance form of South India. Trained under the renowned Guru Saroja Vaidyanathan and the legendary dancer Yamini Krishnamurthy, Rama Vaidyanathan is undoubtedly one of the most profound performers of her generation in the world of dance in India. Kaladharan Viswanath is a leading writer and dance critic and their conversation reveals some deeper insights into the philosophy and practice of Rama Vaidyanathan’s dance and its intersection with music.
Indigenous stewardship as a lifeway1
Authors: Avalos Natalie
Published: August 2020

As the decade closes, Indigenous peoples have re-emerged as a critical voice advocating not just for environmental justice but for an entirely different way of living and being with the world. As the descendants of the original inhabitants of lands now dominated by others, they are often entangled in ongoing struggles to protect their lands and sovereignty. Settler colonialism is now famously understood as a structure, not an event, meaning that colonial projects must be continually re-inscribed through discursive and juridical means in order to naturalize Indigenous dispossession. As a religious studies scholar, I am interested in the ways Native peoples in the United States operationalize religious action as an expression of refusal – a refusal to acquiesce their religious lifeways and rights to their lands.
Reimagining Attawapiskat: Indigenous youth voices, community engagement and mixed-media storytelling
Authors: Wiebe Sarah Marie , Gilpin Erynne M. , Butet-Roch Laurence
Published: August 2020

Widely circulating textual and visual discourses that represent communities shape public perception and awareness. This article discusses a research collaboration between Indigenous and non-Indigenous researchers and artists to reflect on co-creating the Reimagining Attawapiskat project with youth artists. Attawapiskat is an Indigenous community that became the focus of widespread media attention following several State of Emergency declarations due to factors ranging from inhabitable housing conditions to escalating suicide attempts. Informed by Indigenous storytelling research methods and arts-based community-engaged research, the mixed-media storytelling approach advanced here aims to challenge and interrupt mainstream media narratives that frame Attawapiskat as a troubled community constantly in crisis. This collaboration contends with the shadows of Canada’s settler-colonial context through community stories that counter hegemonic portrayals. Reimagining Attawapiskat sheds light on the nuances of community health in Attawapiskat through a collection of youth voices and place-based digital stories that centre Cree life, well-being and culture.
The coral aquarium: A review of Coral Empire by Ann Elias
Authors: Han Lisa Yin
Published: August 2020

Review of: The coral aquarium: A review of Coral Empire by Ann Elias

Coral Empire: Underwater Oceans, Colonial Tropics, Visual Modernity, Ann Elias (2019)

Durham, NC: Duke University Press, 296 pp.,

ISBN 978-1-47800-382-3, p/bk, $26.95
BENTUK DAN MEKANISME PERENCANAAN KEUANGAN DAERAH YANG PARTISIPATIF GUNA MEWUJUDKAN AKUNTABILITAS PUBLIK
Authors: Sulistiawan Anggit , Ispriyarso Budi , Ristyawati Aprista
Published: August 2020

Daerah dalam mengatur dan mengurusi sendiri urusan pemerintahan daerah meliputi desentralisasi fiskal, ekonomi, politik dan administrasi. Keempat elemen desentralisasi ini dimaksudkan untuk mencapai good governance, salah satu unsur dari good governance adalah akuntabilitas publik, yang dapat diwujudkan dengan penerapan pelaksanaan pembangunan daerah berdasarkan perencanaan, pengelolaan, dan pertanggungjawaban keuangan daerah yang baik dalam rangka mengelola dana APBD secara transparan, ekonomis, efisien, efektif dan akuntabel. Penelitian ini mengunakan metode penelitian yuridis normatif dengan mengkaji sumber data dari literatur hukum dan kajian kepustakaan. Penelitian ini bertujuan mengetahui bentuk dan mekanisme perencanaan keuangan daerah, serta pola perencanaan keuangan daerah yang partisipatif guna mewujudkan akuntabiltas publik. Perencanaan keuangan daerah yang baik tentunya mengedepankan transparansi, ekonomis, efisien, dan efektif serta partisipatif dengan melibatkan partisipasi masyarakat dan dapat di pertanggungjawabkan kepada pemerintah dan masyarakat.
HUBUNGAN AGAMA DAN NEGARA MENURUT PANCASILA DAN UNDANG-UNDANG DASAR NEGARA REPUBLIK INDONESIA TAHUN 1945
Authors: Shaleh Ali Ismail , Wisnaeni Fifiana
Published: August 2020

Tulisan ini membahas tentang hubungan agama dan Negara menurut Pancasila dan Undang Undang Dasar 1945. Hubungan antara agama dan Negara  senantiasa menghadirkan sebuah konsekuensi hukum di Indonesia yang berlandaskan ketuhanan yang maha esa, menegaskan bahwa Negara atas nama Konstitusi mengurusi urusan agama dan kepercayaan, sehingga menghadirkan pluralisme hukum di dalam menjalani politik hukum yang harmonis. Negara secara aktif dan dinamis harus menyokong setiap individu-individu sehingga terciptanya kerukunan umat beragama dan tercapai lah hubungan ideal yang di harapkan oleh pendiri Negara.
PERLINDUNGAN HUKUM TERHADAP NASABAH ATAS PENYELENGGARAAN LAYANAN PERBANKAN DIGITAL
Authors: Tarigan Herdian Ayu Andreana Beru , Paulus Darminto Hartono
Published: August 2020

Semakin tingginya persaingan di industri perbankan Indonesia, mendorong banyak bank meningkatkan kualitas pelayanan kepada nasabah dengan memamfaatkan perkembangan teknologi informasi. Inovasi layanan dalam penggunanan teknologi informasi mendorong perbankan untuk memasuki era layanan perbankan digital. Namun, berkembangnya layanan perbankan digital juga meningkatkan resiko yang akan dihadapi oleh bank. Tujuan dari penelitian ini adalah untuk memberikan gambaran penyelenggaraan layanan perbankan digital serta perlindungan nasabah atas resiko dari layanan perbankan digital. Metode yang digunakan penelitian ini adalah metode penelitian hukum yuridis empiris. Hasil dari penelitian ini menunjukan bahwa penyelenggaraan layanan perbankan digital diatur oleh Peraturan OJK No.12/POJK.03/2018 yang merupakan perlindungan preventif terkait perlindungan nasabah. Adanya Peraturan OJK ini diharapkan bank sebagai penyelenggara layanan perbankan digital selalu mengedepankan menejemen risiko dalam penggunaan teknologi informasi. Perlindungan represif berupa pertanggungjawaban pihak bank atas pengaduan dari nasabah pengguna layanan perbankan digital.
KEBIJAKAN KRIMINAL MENGENAI PEMBERIAN GANTI KERUGIAN TERHADAP KORBAN SALAH TANGKAP
Authors: Rohman Syarif Abdul , Rozah Umi
Published: August 2020

Sistem Peradilan Pidana (SPP) Indonesia menggunakan pendekatan due process of law yang bertujuan untuk menegakkan hukum dan keadilan di masyarakat. Kenyataannya yang terjadi saat ini yaitu masih sangat banyak terjadi tindakan aparat penegak hukum yang justru mencederai hukum dan keadilan yang salah satunya adalah tindakan salah tangkap.Permasalahan dalam artikel ini, yaitu mengenai formulasi saat ini dan yang akan datang tentang ganti kerugian terhadap korban salah tangkap. Metode penelitian menggunakan penelitian yuridis normatif atau studi kepustakaan.Kedudukan korban salah tangkap dalam sistem peradilan pidana Indonesia ternyata relatif kurang diperhatikan, dan belum memberikan perlindungan secara langsung terhadap korban. Ketentuan hukum mengenai perlindungan terhadap korban salah tangkap tersebut meliputi Undang-undang tentang Kekuasaan Kehakiman, Udang-undang tentang Hak Asasi Manusia, KUHP, KUHAP dan Peraturan Pelaksanaanya. Lemahnya kemampuan profesionalisme penyidik, berupa pelanggaran terhadap prosedur upaya paksa yang tidak menghormati asas praduga tidak bersalah, kekeliruan tindakan identifikasi korban pembunuhan yang tidak akurat, serta adanya kekhilafan hakim atau kekeliruan yang nyata dalam mempertimbangankan yudex facti pengadilan, merupakan faktor penyebab terjadinya salah tangkap dalam tindak pidana pembunuhan. Kebijakan Pemberian Ganti Kerugian Terhadap Korban Salah Tangkap.
KEBIJAKAN FORMULASI PERTANGGUNGJAWABAN PIDANA KORPORASI TERHADAP PERBUATAN TRADING IN INFLUENCE SEBAGAI TINDAK PIDANA KORUPSI
Authors: Sari Ratna Kumala , Jaya Nyoman Serikat Putra
Published: August 2020

Salah satu jenis tindak pidana korupsi yang akhir-akhir ini diperbincangkan yaitu trading in influence. Terlebih pada saat ini tindak pidana trading in influence tidak dilakukan hanya oleh seseorang, melainkan suatu korporasi yang sudah terstruktur dan memiliki visi yang kuat. Mengingat trading in influence menjadi bagian dari tindak pidana korupsi, maka diperlukan kebijakan formulasi hukum pidana khususnya mengenai formulasi tindak pidana. Jenis korupsi ini yang sebenarnya sudah diatur dalam UNCAC, tetapi belum dirumuskan dalam ketentuan hukum positif Indonesia meskipun sudah diratifikasi. Berdasarkan hal tersebut, dalam penelitian ini merumuskan permasalahan yaitu: 1) Bagaimana kebijakan formulasi pertanggungjawaban pidana korporasi terhadap perbuatan trading in influence dalam hukum positif di Indonesia saat ini? dan 2) Bagaimana pertanggungjawaban pidana korporasi terhadap perbuatan trading in influence sebagai tindak pidana korupsi yang akan datang? Penelitian ini menggunakan metode yuridis normatif. Hasil penelitian menjelaskan bahwa saat ini formulasi hukum pidana trading in influence tidak terdapat dalam Kitab Undang-Undang Hukum Pidana; Undang-undang Nomor 31 Tahun 1999 jo Undang-undang Nomor 20 Tahun 2001 tentang Pemberantasan Tindak Pidana Korupsi. Sementara dalam konsep KUHP yang sedang dibahas saat ini telah merumuskan perbuatan trading in influence, sehingga dapat mengakomodir kekurangan dalam peraturan perundang-undangan yang berlaku saat ini.
PERAN BADAN NASIONAL PENANGGULANGAN TERORISME DALAM PEMBERANTASAN TERORISME DI INDONESIA
Authors: Zulfikar Muhammad , Aminah Aminah
Published: August 2020

Terorisme merupakan suatu tindak pidana atau kejahatan luar biasa yang menjadi perhatian dunia sekarang ini terutama di Indonesia. Terorisme yang terjadi akhir-akhir ini memiliki keterkaitan ideologis, sejarah dan politis serta merupakan bagian dari dinamika lingkungan strategis pada tataran global dan regional. Kendatipun aksi terorisme yang terjadi di berbagai daerah dalam beberapa tahun terakhir ini kebanyakan dilakukan oleh orang Indonesia dan hanya sedikit aktor-aktor dari luar. Penelitian ini mengunakan metode penelitian yuridis normatif dengan mengkaji sumber data dari literatur hukum dan kajian kepustakaan. Penelitian ini bertujuan mengetahui tentang peran BNPT dan pihak-pihak yang berwenang dalam pemberantasan terorisme serta peran masyarakat, organisasi masyarakat yang ada di Indonesia dalam upaya menangani terorisme. Yaitu mencermati perkembangan kekinian, BNPT terus menggalang berbagai elemen bangsa untuk bersama melawan radikalisme, menggalakkan kontra radikalisasi, terus bersinergi dengan lembaga pemerintah lainnya serta berbagai media untuk menyatukan dan menyamakan persepsi dalam menghadapi ancaman tersebut. Adapun Peran dari media dalam pemberantasan terorisme tidak cukup efektif untuk menyeimbangkan dan memurnikan media massa dari paham radikalisme, sinergitas peran dengan berbagai pihak juga sangat diperlukan. Olehnya diperlukan peran masyarakat, organisasi masyarakat, khususnya Kepala Daerah, tokoh politik, dan para ulama yang ada di setiap daerah secara aktif ikut berpartisipasi dalam kegiatan pemberantasan terorisme di Indonesia.
ANALISIS YURIDIS PERLINDUNGAN HUKUM TENAGA MIGRAN KORBAN PERDAGANGAN MANUSIA OLEH PEMERINTAH INDONESIA
Authors: Yusitarani Safrida
Published: August 2020

Pekerja migran Indonesia memberikan kontribusi besar terhadap perekonomian Indonesia. Mengingat Indonesia merupakan negara asal pekerja migran kedua terbesar se-ASEAN. Berbagai peraturan telah dibuat sebagai bentuk upaya perlindungan oleh pemerintah Indonesia. Namun masih banyak ditemukan masalah yang muncul, diantarnaya adalah perdagangan manusia. Metode penelitian dalam artikel ini yaitu yuridis normatif dengan menggunakan pendekatan undang-undang (statue approach) dan pendeketan konseptual (conceptual approach). Data yang digunakan dalam penulisan ini adalah data sekunder, yaitu buku-buku perpustakaan, peraturan perundang-udangan, karya ilmiah, artikel-artikel, serta dokumen yang berkaitan dengan materi penelitian. Upaya pemerintah memberantas perdagangan manusia terhadap tenaga kerja Indonesia antara lain mengeluarkan berbagai instrumen hukum, melakukan kerjasama bilateral, cregional, maupun multilateral terutama negara tujuan penempatan TKI, dan bekerja sama dengan lembaga non pemerintahan. Upaya pemerintah dalam memberikan perlindungan hukum kepada TKI korban perdagangan manusia adalah dengan pemberian restitusi dan kompensasi, layanan konseling dan pelayanan atau bantuan medis, bantuan hukum dan pemberian informasi serta menjamin pemenuhan hak-hak TKI korban perdagangan manusia, seperti kerahasian identitas hingga hak untuk mendapatkan rehabilitasi.
Penegakan Hukum Keimigrasian Terhadap Penyalahgunaan Visa Izin Tinggal Kunjungan Lewat Batas Waktu (Overstay) Pada Warga Negara Asing
Authors: Muhlisa Aisyah Nurannisa , Roisah Kholis
Published: August 2020

Imigrasi merupakan instansi yang berwenang menyelenggarakan pengawasan lalu lintas orang masuk dan keluar dari wilayah Indonesia. Pemerintah Indonesia berupaya mendukung pertumbuhan ekonomi melalui sektor pariwisata guna meningkatkan sumber devisa. Sehingga pemerintah memberikan bebas visa kunjungan singkat kepada warga negara asing. Visa merupakan izin (persetujuan) untuk masuk, berwujud cap dan paraf yang dibubuhkan oleh pejabat perwakilan bersangkutan pada paspor pemohon. Orang asing yang masuk ke Indonesia memanfaatkan kemudahan bebas visa kunjungan dengan melakukan pelanggaran keimigrasian seperti penyalahgunaan batas waktu izin tinggal untuk melaksanakan kegiatan-kegiatan yang tidak sesuai aturan hukum keimigrasian. Penelitian ini bertujuan mengkaji penegakan hukum oleh keimigrasian kepada orang asing yang melakukan penyalahgunaan visa kunjungan lewat batas waktu.  Hasil penelitian ini melihat bagaimana penegakan hukum keimigrasian bertindak sesuai Undang-Undang Nomor 6 Tahun 2011 tentang Keimigrasian dan Peraturan Presiden Nomor 21 Tahun 2016 tentang Bebas Visa Kunjungan, dengan cara pengawasan kelengkapan prosedur administratif izin tinggal kunjungan orang asing, dan menindak secara administratif kepada yang melanggar izin tinggal dengan mengenakan kepada orang asing membayar biaya beban, dan pemulangan kenegara asal.
Perkembangan Sistem Pemerintahan dan Konsep Kedaulatan Pasca Revolusi Perancis Terhadap Hukum Internasional
Authors: Christmas Sandy Kurnia , Purwanti Evi
Published: August 2020

Revolusi Perancis merupakan sebuah peristiwa yang menyebabkan perubahan sosial dan pergeseran budaya politik. Revolusi ini membentuk paham-paham seperti Liberalisme, Demokrasi, dan Nasionalisme yang berdampak pada perubahan sistem pemerintahan dan kedaulatan. Bagaimana pola sistem pemerintahan Pra-Revolusi Perancis, serta apa perubahan yang berdampak membawa perkembangan hukum internasional Pasca Revolusi Perancis. Artikel ini bertujuan untuk mengkaji secara historis bagaimana sebuah peristiwa sejarah membawa perubahan yang signifikan terhadap pola sistem pemerintahan yang sampai sekarang digunakan. Metode penelitian ini menggunakan penelitian hukum normatif, dimana pengkajian menggunakan pendekatan konseptual dan pendekatan historis. Hasil penelitian ini menyimpulkan bahwa paham-paham yang terbentuk saat terjadinya Revolusi Perancis, seperti Liberalisme, Demokrasi, dan Nasionalise berdampak besar terhadap perubahan sistem pemerintahan yang lebih mengutamakan kepentingan rakyat serta perkembangan hukum internasional. Pola sistem pemerintahan Pra-Revolusi Perancis berbentuk Monarki nyatanya banyak mengalami kegagalan dan dianggap terlalu menekan rakyat. Adanya perubahan terhadap pola sistem pemerintahan yang dipicu oleh Revolusi Perancis dianggap sebagai revolusi rakyat karena banyak menciptakan berbagaii bentuk tatanan konsep negara yang baik yang menjadi cita-cita rakyat yang berpengaruh hingga sekarang.
Kebijakan Hukum Pidana dalam Pengaturan dan Penanggulangan Ujaran Kebencian (Hate Speech) di Media Sosial
Authors: Azhar Ahmad Faizal , Soponyono Eko
Published: August 2020

Perkembangan teknologi dan informatika berdampak pada kebebasan berpendapat dan penyampaian informasi di Indonesia seringkali meresahkan individu maupun kelompok seperti Suku, Agama, Ras, Antar Golongan. Tujuan penulisan ini membahas Kebijakan Hukum Pidana Dalam Pengaturan Dan Penanggulangan Ujaran Kebencian (Hate Speech) di Media Sosial masa saat ini dan masa yang akan datang. Kebijakan hukum pidana penyebaran ujaran kebencian dalam KUHP; UU Nomor 1 Tahun 1946; UU Nomor 1/PNPS Tahun 1965; UU Nomor 40 Tahun 1999; UU Nomor 32 Tahun 2002; UU Nomor 40 Tahun 2008; UU Nomor 19 Tahun 2016 masih banyak terdapat kelemahan yuridis dan dari kebijakannya belum sistemik, dan belum mampu maksimal dalam menaggulangi kejahatan penyebaran ujaran kebencian melalui sarana sistem hukum pidana. Pada konsep KUHP yang sedang digagas telah mengakomodir seluruh kekurangan yang terdapat dalam peraturan perundang-undangan saat ini sebagai pengaturan dan penanggulangan ujaran kebencian.
Red Cell Distribution Width (RDW) as a Marker of Disease Activity in Patients with Hairy Cell Leukemia
Authors: Chrobák Ladislav , Žák Pavel , Podzimek Karel , Stránský Pravoslav
Published: August 2020

Red cell distribution width (RDW) was examined in 18 patients with hairy cell leukemia (HCL) treated with 2- chlorodeoxyadenosine (2-CdA), in 5 patients treated with Interferon alpha (IFN-alpha) and in 9 patients subjected to splenectomy. Out of 18 patients treated with 2-CdA one patient was excluded of the study because of association of HCL with acquired sideroblastic anemia. In the remaining 17 patients the mean value of RDW before terapy was 18.8% (range 13.5% to 25.0%) and dropped after successful theapy after 6 to 12 months to the mean value of 13.6% (range 11.2% to 17.9%) and after 18 months to 13.4% (range 12.6% to 14.7%) (p = 0.00015 and p = 0.00049 respectivelly). The hemoglobin level increased from the mean value of 119 g/l (range 99 g/l to 157 g/l) before therapy to the mean value of 145.9 g/l (range 127 g/l to 172 g/l) after 6 to 12 months and after 18 months to 147.8 g/l (range 132 g/l to 168 g/l) (p = 0.000017 and p = 0.00036 respectively). The same trend was observed in the group of patients treated with IFN-alfa. The RDW decreased from the mean value of 21.3% (range 18.8% to 28.7%) to the mean value of 15.3% (range 12.4% to 16.7%), (p = 0.031). The hemoglobin level increased in this group of patients from the mean value of 115 g/l (range 98 g/l to 127 g/l) to the mean value of 136 g/l (range 127 g/l to 146 g/l) (p = 0.031). In 9 patients in complete hematologic remission 34 to 293 months after splenectomy the mean value of RDW was 13.9% (range 13.0% to 15.5%). Conclusion: Increased RDW in HCL is associated with active disease and is reversible after successful therapy. This phenomenon has not been reported in the literature yet. Preliminary results show that the increase of RDW may be due to the dyserythropoiesis.
Themata in science and in common sense
Authors: Marková Ivana
Published: August 2020

Human thinking is heterogeneous, and among its different forms, thinking in dyadic oppositions is associated with the concept of themata. Gerald Holton characterises themata as elements that lie beneath the structure and development of physical theories as well as of non-scientific thinking. Themata have different uses, such as a thematic concept, or a thematic component of the concept; a methodological (or epistemological) thema; and a propositional thema. Serge Moscovici has placed the concept of themata in the heart of his theory of social representations which is based on ‘natural thinking’ and on forms of daily knowing, including common sense. In this article I shall explore some features of thematic concepts and of methodological themata in scientific theories and in common sense. More specifically, I shall refer to the significance of the methodological (or epistemological) thema the Self and Other(s) in common-sense thinking and in social practices.