bluuebunny/crossref_metadata_2025 huggingface dataset:
Sensitivity and diversity analysis of Nilakottai ecotype tuberose under ethyl methane sulphonate exposure: Morphological variations and antioxidant activity
Authors: Sripriya Malepati S N V S Bhargavi , Chitra R , Ganga M , Kalaiyarasi R , Boopathi N Manikanda , Uma D , Mirunalini S P
Published: January 2025

The Nilakottai ecotype, a renowned indigenous variety of tuberose cultivated by farmers in the Dindigul district, is distinguished by its unique fragrance. To further enhance the floral characteristics of this tuberose ecotype, mutation breeding was undertaken at Tamil Nadu Agricultural University, Coimbatore. The present study involved 11 treatments, each replicated 3 times, using a CRD (completely randomized design). The results revealed that the LD50 for the Nilakottai ecotype with ethyl methane sulphonate (EMS) was 0.42 %. As the EMS concentration increased, there was a reduction in both sprouting and survival, with a 38.2 % and 56.24 % decrease respectively, at the highest concentration. Morphological parameters such as root length, shoot length, leaf length, leaf width and the number of leaves also showed a decrease of 78.80 %, 71.16 %, 87.29 %, 61.90 % and 62.99 % respectively, compared to the control at 1.0 % EMS. Pollen viability studies indicated a reduction in viability with increasing EMS concentration, showing 85.74 % viability in the control group and only 31.54 % at 1.0 % EMS. Analysis of antioxidant enzymes revealed a significant increase in catalase (CAT), peroxidase (POD) and superoxide dismutase (SOD) levels with higher EMS concentrations. Overall, EMS had a pronounced effect on various traits, including germination, growth and antioxidant activity.
Pink Pigmented Facultative Methylotrophs (PPFMs) improve rooting in black pepper (Piper nigrum L.) cuttings and mitigate drought stress
Authors: ManjuBhargavi Yarlagadda , Rajan S Anu , Chitra N , Soumya V I , Beena R , Anith K N
Published: January 2025

Black pepper, a major spice cultivated across the globe, is droughtsensitive, and water stress often results in plant fatality. Pink Pigmented Facultative Methylotrophs (PPFMs), the plant growth-promoting phyllosphere bacteria, can induce physiological changes in plants, making them more tolerant to various stresses. PPFMs from phyllosphere of black pepper were isolated, characterized and, screened for plant growth promotion and drought stress mitigation in black pepper. Sixty PPFM isolates were obtained by leaf imprinting and plating on 5 % PEG 6000 amended Methanol Mineral Salts medium. Screening of isolates for plant growth promotion was based on producing indole acetic acid, gibberellic acid, extracellular ammonia and 1-aminocyclopropane-1-carboxylate deaminase activity in vitro. The influence of three best performing isolates, identified by 16SrRNA sequencing as Methylobacterium aerolatum PNPPFM60, Methylorubrum aminovorans PNPPFM59 and Methylorubrum zatmanii PNPPFM44, on growth and establishment of black pepper cuttings was investigated. M. aerolatum PNPPFM60 recorded the highest biometric parameters. After the foliar application on 90th DAP the soil moisture level was maintained at field capacity for 15 days and then irrigation was withdrawn. The control plants showed symptoms of drought after 3 days of withdrawing irrigation while the PPFM treated plants remained green with higher RWC and higher cell membrane integrity till 7th day. The antioxidant enzymes were highest in plants treated with M. aerolatum PNPPFM60. PPFMs could improve growth of black pepper and mitigate drought stress in early stages of establishment of black pepper and has the potential to be developed as a bioformulation.
Impact of drone technology on agriculture - farmers' perception analysis
Authors: Barathkumar R , Selvanayaki S , Deepa N , Kannan P , Prahadeeswaran M
Published: January 2025

Unmanned aerial vehicles (UAVs), or drones, are revolutionizing agricultural practices by enhancing precision and efficiency in crop management. This study examines the impact of drone technology on agriculture in Coimbatore district, Tamil Nadu, focusing on farmers' perceptions and the extent of drone adoption. Covering a sample size of 120 farmers, the research explores various aspects of drone usage, including its benefits and challenges. Key advantages include reduced chemical usage, improved crop monitoring, precise irrigation, increased yields and water conservation. Government initiatives like the Kisan Drone program support the adoption of agricultural drones through subsidies and financial aid. However, high initial costs, technical complexity and regulatory barriers limit widespread adoption, particularly among small and marginal farmers. Custom hiring centres and enhanced government support are identified as potential solutions. Statistical methods such as binary logistic regression, propensity score matching and factor analysis are used to analyze adoption patterns and barriers. Findings reveal that drone spraying is the most common application, with higher awareness and adoption rates among educated farmers. The study concludes with recommendations to improve accessibility, reduce costs and expand training programs to benefit farmers across all socioeconomic segments.
Od „źródła muz” do siedziby pogańskiego tyrana. Bizancjum w wybranych ossolińskich starych drukach XV–XVII wieku
Authors: Szymański Konrad K.
Published: January 2025

W kolekcji starych druków Ossolineum znajduje się wiele dzieł opisujących historię i kulturę Bizancjum. Możemy znaleźć tu pierwsze drukowane opisy zdobycia Konstantynopola w 1453 roku, XV-wieczne przedstawienia bizantyńskiej stolicy, opisy drogocennych ilustrowanych greckich manuskryptów, jak również polskie relacje z podróży na Wschód z przełomu XVII i XVIII wieku. Metoda i cel: Analiza treści omawianych tu woluminów pozwala ukazać, jak na przestrzeni XV–XVII stulecia Konstantynopol z ostatniego bastionu chrześcijańskiej tradycji i kultury antycznej stał się egzotyczną siedzibą pogańskiego tyrana. „Źródło muz”, gdzie humaniści poszukiwali cennych manuskryptów, i repozytorium świętych relikwii, dokąd zmierzali liczni pielgrzymi, stało się bazarem orientalnych rozmaitości, pełnym tajemnic, niezwykłych przypraw i obcych zwyczajów. Wnioski: Niniejsze rozważania prezentują, jak od XVI stulecia tematyka prac dotyczących obszarów wschodniego Rzymu, przechodząc do sfery badań naukowych jako historia „greckiego cesarstwa”/ Bizancjum, w wymiarze popkulturowym zastępowana była szerszym zainteresowaniem nad Orientem. Podejmowana w wybranych starych drukach tematyka uwidacznia, jak w oczach nowożytnych Europejczyków Cesarstwo Wschodniorzymskie nieuchronnie traciło te cechy swego dawnego oblicza, z którymi Zachód mógłby się identyfikować. Bizancjum stawało się coraz bardziej światem obcym, skomplikowanym i wydumanym. Prezentowane tutaj woluminy omówiono również pod względem fizycznym, przybliżając sylwetki ich dawnych właścicieli oraz ich bibliotek.
Zagadkowy rękopis muzyczny PL-Pu Rpm7642 i znaleziony w nim spis muzyków jezuickich z pierwszej połowy XVIII wieku
Authors: Walter-Mazur Magdalena
Published: January 2025

Cele artykułu: rozpoznanie zawartości rękopisu (repertuar, proweniencja, datowanie; wartość informacyjna w kontekście historii kultury muzycznej Rzeczpospolitej); ustalenie pochodzenia spisu muzyków i identyfikacja muzyków. Metody: metody krytyki zewnętrznej i wewnętrznej źródła muzycznego, metody historyczne. Wyniki: ustalenie, że rękopis PL-Pu Rpm7642 składa się z fragmentów ośmiu innych, powstałych przynajmniej w trzech różnych ośrodkach rękopisów, przybliżone ustalenie ich repertuaru; wskazanie na przyczynę tak nietypowej zawartości: związku z działalnością prof. Adolfa Chybińskiego, najprawdopodobniej poprzedniego właściciela rękopisu; zidentyfikowanie spisu muzyków jako pochodzącego z krakowskiej bursy muzycznej jezuitów, datowanego na rok 1735 – oprócz muzyków znanych z innych źródeł badany rękopis przynosi informacje o czterech nowych muzykach oraz uzupełnia dane na temat ośmiu już wcześniej odnotowanych.
Hearing exotic smooth structures
Authors: Cavenaghi Leonardo F. , do Ó João Marcos , Sperança Llohann D.
Published: January 2025

This paper explores the existence and properties of basic eigenvalues and eigenfunctions associated with the Riemannian Laplacian on closed, connected Riemannian manifolds featuring an effective isometric action by a compact Lie group. Our primary focus is on investigating the potential existence of homeomorphic yet not diffeomorphic smooth manifolds that can accommodate invariant metrics sharing common basic spectra. We establish the occurrence of such scenarios for specific homotopy spheres and connected sums. Moreover, the developed theory demonstrates that the ring of invariant admissible scalar curvature functions fails to recover the smooth structure in many examples. We show the existence of homotopy spheres with identical rings of invariant scalar curvature functions, irrespective of the underlying smooth structure.
Supplier selection models using fuzzy hybrid methods in the clothing textile industry
Authors: Lahdhiri Mourad , Jmali Mohamed , Babay Amel , Ahlaqqach Mustapha , Hlyal Mustapha
Published: January 2025

Application of models for supplier assessment and selection in the clothing industry remains relatively underexplored. To fill this gap, this research study introduces the following fuzzy hybrid models for evaluating and selecting suppliers for clothing manufacturing firms: fuzzy set theory, Analytic Hierarchy Process method–fuzzy-Technique for Order of Preference by Similarity to Ideal Solution (AHP–fuzzy-TOPSIS), AHP–fuzzy-Weighted Sum Model (WSM), and AHP–fuzzy-Weighted Product Mean (WPM). Criteria weights were established utilizing these models, which were applied to identify the optimal supplier. A practical study was conducted within a clothing firm to evaluate the effectiveness of these fuzzy hybrid models. The main results reveal that the AHP–fuzzy-TOPSIS model outperforms the AHP–fuzzy-WSM and AHP–fuzzy-WPM models in selecting the optimal alternative. Indeed, this approach has the potential to be adapted to different industrial sectors, considering the specific criteria and conditions that govern their supplying processes.
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA)
Authors: Buchta Christoph , De la Salle Barbara , Marrington Rachel , Aburto Almonacid Andrés , Albarède Stéphanie , Badrick Tony , Bullock David , Cobbaert Christa M. , Coucke Wim , Delatour Vincent , Faria Ana Paula , Geilenkeuser Wolf-Jochen , Griesmacher Andrea , Huggett Jim F. , Ianovska Viktoriia , Kammel Martin , Kessler Anja , Körmöczi Günther F. , Meijer Piet , Miranda Armandina , Patel Dina , Pezzati Paola , Sandberg Sverre , Schennach Harald , Schweiger Christian R. , Schwenoha Karin , Spannagl Michael , Sung Heungsup , Thelen Marc , Weykamp Cas , Zeichhardt Heinz , Restelli Veronica , Perrone Lucy A.
Published: January 2025

External quality assessment (EQA) enhances patient safety through the evaluation of the quality of laboratory-based and point of care testing. Regulatory agencies and accreditation organizations utilize the results and the laboratory’s response to them as part of assessing the laboratory’s fitness to practice. In addition, where EQA samples are commutable and the assigned value has been determined using reference measurement procedures (RMPs), EQA data contributes to the verification of metrological traceability of assays as part of the post-market surveillance of in vitro diagnostic (IVD) medical devices (IVD-MDs). More broadly, the scientific and medical communities use EQA data to demonstrate that medical laboratory examination procedures are fit for clinical purposes, to evaluate common reference intervals, and inclusion of data in clinical databases. Scientific groups, the IVD industry, reference laboratories and National Metrology Institutes can work with EQA providers to identify measurands, which should urgently be supported by the development of reference materials or methods. The ability of health systems to respond effectively to fast-evolving medical challenges, such as the Coronavirus Disease-19 (COVID-19) pandemic, is reliant on EQA to demonstrate confidence in the performance of new laboratory methods and testing services. EQA providers are uniquely positioned to assess the performance of IVD-MDs in addition to individual laboratories and testing sites. Although the primary focus of EQA providers remains the improvement of the performance of individual laboratories, there are many stakeholders who benefit from EQA performance data.
Efficient ecological function optimization for endoreversible Carnot heat pumps
Authors: Su Yiwen , Chen Lingen , Ge Yanlin , Feng Huijun
Published: January 2025

According to the definition of exergy-based efficient ecological-function (EBEEF) which is proposed as product of exergy-based ecological-function (EF) and coefficient of performance (COP) in previous literature, this paper applies the EBEEF to analyze and optimize performance of endoreversible Carnot heat-pumps (ECHPs). Via the ECHP cycle model established in previous literature, EBEEF expression for ECHP cycle model is deduced, relationships among the EBEEF and heating load (HTL) and COP are researched, and performance comparison for ECHP cycle working at the maximum EBEEF and the maximum EF conditions are performed. Results show that relationships among the EBEEF and the HTL and COP are parabolic like ones and the design points of the larger COP and HTL should be selected for designing heat pumps. When the maximum EBEEF is taken as primary objective, the optimized ECHP cycle can improve its COP and reduce its entropy-generation-rate by sacrificing a small amount of its HTL. The EBEEF not only considers the trade-off between the HTL and entropy-generation-rate, but also considers the trade-off between HTL and COP.
Metacavities by harnessing the linear-crossing metamaterials
Authors: Wu Jiaju , Guo Zhiwei , Qi Xin , Wei Qian , He Li , Fang Kai , Sun Yong , Li Yunhui , Chen Yuguang , Jiang Haitao , Chen Hong
Published: January 2025

The formed optical cavity mode intensively relies on the size and geometry of optical cavity. When the defect or impurity exists inside the cavity, the formed cavity mode will be destroyed. Here, we propose a metacavity consisting of arrays of linear-crossing metamaterials (LCMMs) with abnormal dispersion, where each LCMM offers both the directional propagation channel for all incident angles and the negative refraction across its neighboring LCMMs. Such metacavity can be efficiently excited by a point source, where the excited wave vector components propagate along the same optical path in the cavity. More importantly, the proposed metacavity possesses the remarkable feature of partial defect immunity and geometry robustness. Assisted by two-dimensional transmission lines with loaded-circuit elements, a metacavity with partial defect immunity has been experimentally realized. Our work offers a new avenue for designing optical resonators excited by the point source in integrated photonics, which is very useful for high-efficiency filters, ultrasensitive sensors, and enhancement of light–matter interactions.
Eye Movements during Measurements of Visual Vertical in the Poststroke Subacute Phase
Authors: Arima Yasuaki , Nakamura Kae , Mori Kimihiko , Hashimoto Shingo , Wakida Masanori , Ishii Hironori , Hase Kimitaka
Published: January 2025

The subjective visual vertical (VV), the visually estimated direction of gravity, is essential for assessing vestibular function and visuospatial cognition. In this study, we aimed to investigate the mechanisms underlying altered VV perception in stroke participants with unilateral spatial neglect (USN), specifically by examining their eye movement patterns during VV judgment tasks. Participants with USN demonstrated limited eye movement scanning along a rotating bar, often fixating on prominent ends, such as the top or bottom. This suggests a reflexive response to visually salient areas, potentially interfering with accurate VV perception. In contrast, participants without USN showed broader scanning around the center of the bar. Notably, participants with USN without frontal lobe lesions occasionally exhibited extended scanning that included the bar’s center, which was associated with accurate VV judgments. These findings suggest that (1) a tendency to fixate on peripheral, prominent areas and (2) frontal lobe involvement in disengaging and redirecting spatial attention may influence VV perception in USN. Based on these results, targeted rehabilitation strategies that encourage individuals with USN to extend their visual scanning beyond prominent endpoints and include central areas could improve VV accuracy. This study highlights the specific eye movement behaviors contributing to VV misperception, emphasizing the importance of training that broadens scanning to improve VV perception effectively.
Neural correlates of perceptual plasticity in the auditory midbrain and thalamus
Authors: Ying Rose , Stolzberg Daniel J. , Caras Melissa L.
Published: January 2025

Hearing is an active process in which listeners must detect and identify sounds, segregate and discriminate stimulus features, and extract their behavioral relevance. Adaptive changes in sound detection can emerge rapidly, during sudden shifts in acoustic or environmental context, or more slowly as a result of practice. Although we know that context- and learning-dependent changes in the sensitivity of auditory cortical (ACX) neurons support many aspects of perceptual plasticity, the contribution of subcortical auditory regions to this process is less understood. Here, we recorded single- and multi-unit activity from the central nucleus of the inferior colliculus (ICC) and the ventral subdivision of the medial geniculate nucleus (MGV) of male and female Mongolian gerbils under two different behavioral contexts: as animals performed an amplitude modulation (AM) detection task and as they were passively exposed to AM sounds. Using a signal detection framework to estimate neurometric sensitivity, we found that neural thresholds in both regions improved during task performance, and this improvement was largely driven by changes in firing rate rather than phase locking. We also found that ICC and MGV neurometric thresholds improved as animals learn to detect small AM depths during a multi-day perceptual training paradigm. Finally, we reveal that in the MGV, but not the ICC, context-dependent enhancements in AM sensitivity grow stronger during perceptual training, mirroring prior observations in the ACX. Together, our results suggest that the auditory midbrain and thalamus contribute to changes in sound processing and perception over rapid and slow timescales.

Significance statementWhat a listener hears depends on several factors, such as whether the listener is attentive or distracted, and whether the sound is meaningful or irrelevant. Practice can also shape hearing by improving the detection of particular sound features, as occurs during language or musical learning. Understanding how changes in sound perception arise in the brain is important for developing strategies to optimize healthy hearing, and for treating disorders in which these processes go awry. We report that neurons in the auditory midbrain and thalamus exhibit rapid shifts in sound sensitivity that depend on the sound’s behavioral relevance, and slower improvements that emerge over several days of training. Our results suggest that subcortical areas make an important contribution to flexible hearing.
Sickly Sweet
Authors: Lau Courtney
Published: January 2025

A sickly sweet scent lingers in Arnold Genthe’s Old Chinatown photographs (1896–1906). Genthe, a German immigrant who was known for his portraits of presidents of the United States and prominent businessmen, began his artistic career by taking pictures on the streets of San Francisco’s Chinatown. While Genthe’s archive is celebrated for its soft-focus pictorialist style, less attention has been paid to the racialized discourse on Chinese atmospheres that produced this aesthetic effect. Contextualizing these images within the US anxiety about the “yellow peril” in the early twentieth century, which rendered the Chinese as noxious to the national atmosphere, this essay demonstrates that Genthe’s style emerged from these racialized fears of toxic air. Moving between the photographer’s images, his published memoir, and contemporaneous public health records, I chart an irresolvable sickly sweet scent in this visual archive through a method that I term “atmo-speculation.” Focusing on a lesser-known portrait by Genthe of an anonymous nude woman, I trace fetid air as a critical aesthetic through which we can sense insurgent forms of Chinese femininity in the US. Augmenting recent scholarship on minoritarian form, which approaches race through affect and sensation, I argue that feminist sensorial engagements with Genthe’s Old Chinatown photographs disturb national ideals of contained citizenship.
Deterrence, Assurance, and Countermeasures
Authors: Chen Xin-You , Lin Thung-Hong , Chen Chih-Jou Jay
Published: January 2025

This study examines the consequences of US House Speaker Nancy Pelosi’s 2022 Taiwan visit and China’s military response, using survey data from 2,027 respondents in Taiwan and 4,575 in Shanghai. The visit achieved its goals: assuring Taiwan’s public and creating a deterrent effect on China’s public. In response, China’s military exercises aimed to alleviate domestic concerns about US involvement (counter-deterrence) and to undermine Taiwan’s confidence in US assurances (counter-assurance). The exercises had a slight counter-assurance effect but no significant counter-deterrence. This study highlights the complex interplay between military and non-military strategies in the Taiwan Strait’s security environment and their roles in geopolitical stability.
Green Extractivism’s New Frontiers
Authors: Deberdt Raphael
Published: January 2025

The scramble for critical minerals needed for the low-carbon transition stretches from Congolese cobalt mines to plans for extracting ores from asteroids and the deep seabed. Companies are also reopening old mines to extract the increasingly valuable and strategically important minerals. These intensifying activities threaten to sacrifice vulnerable ecosystems and populations in the name of saving the planet.
The Democratic Challenges in Global Governance of AI
Authors: Erman Eva , Furendal Markus
Published: January 2025

Artificial intelligence is bound to have a significant impact on societies and global politics. Given that everyone is affected by the advent of AI technology, its development and deployment should arguably be under democratic control. This essay describes the global AI governance regime complex that has developed in recent years, and discusses what should be democratically governed, who should have a say, and how this should happen. The answers to these questions depend on why we value the democratic ideal and what reasons there are to extend it to the AI domain.
The ‘Global’ in Anti-Gender Mobilization
Authors: Chen Yo-Ling
Published: January 2025

Campaigning against transgender rights, Taiwan’s No Self ID movement has borrowed charged rhetoric from Western counterparts. Yet polls show it has yet to win over public opinion.
The Right of Dissent
Authors: Commager Henry Steele
Published: January 2025

Excerpted from an essay by Henry Steele Commager in the October 1955 issue of Current History.
“Interested by nobody but Mary Crawford”
Authors: Gilligan Christina J.
Published: January 2025

Christina J. Gilligan, “‘Interested by nobody but Mary Crawford’: Identification and Critique in Mansfield Park” (pp. 157–181)

Critics often characterize Jane Austen’s Mansfield Park (1814) as a conservative outlier in her oeuvre. In this article, I argue that Mansfield Park represents a shift not in Austen’s ethico-political commitments but rather in the way she affectively structures the novel in relation to the protagonist. While in Sense and Sensibility and Pride and Prejudice, Austen aligns merit and attention in her identificatory heroines, in Mansfield Park, she affords heroic attention to Fanny Price while reserving heroic merit for Mary Crawford. Through this bold decoupling of attention from merit, Austen destabilizes the way meaning is communicated in her novels. No longer can readers rely on an only slightly qualified affective identification with the heroine to comprehend the novel’s project. Rather, readers must now engage for themselves in the kind of critical reading practices modeled by Mary and by Austen’s earlier heroines to grasp Mansfield Park’s critiques both of the Bertram family’s abuse of Fanny and of Fanny’s own limited ethical program. These critiques are bodied forth not through Fanny, who secures her marriage to Edmund through her own unethical reading failures, but instead through Mary, who shares the novel’s commitment to taking seriously the injustices of gender-based precarity and whose open-ended escape from Mansfield has been critically mischaracterized as a punishment for misbehavior.
Grob iz starijeg željeznog doba s groblja Nakovana – Zmijna (poluotok Pelješac)
Authors: Perkić Domagoj , Potrebica Hrvoje , Dizdar Marko , Pamić Ivan
Published: January 2025

Prapovijesno gradinsko naselje Grad u Nakovani jedno je od najistaknutijih naselja iz brončanog i željeznog doba na južnom dijelu istočnojadranske obale. O njegovoj važnosti kao i kompleksnom kulturnom krajoliku u kojem se nalazi, osim do sada pronađene materijalne ostavštine, svjedoče i brojne kamene gomile koje se nalaze u okolici Grada, posebno na brdu Zmijnoj. S obzirom na pretpostavljenu kontinuiranu naseljenost Grada sve do kraja željeznog doba, očekivalo se i postojanje ravnih grobova, što su istraživanja provedena 2020. godine i potvrdila. Na južnim padinama brda Zmijne otkrivena su dva groba na ravnom smještena u blizini mlađih kamenih gomila. Grob smješten pri vrhu brda, na osnovi pronađenih nalaza, datiran je u starije željezno doba. Ostatci više pokojnika bili su položeni u prirodnu udubinu i pokriveni većim kamenim blokovima. U grobu su, osim keramičkih ulomaka, pronađeni predmeti nakita i nošnje koji upućuju na kulturne kontakte sa zaleđem te prostorom zapadnog Balkana na kojem je starije željezno doba obilježeno razvojem glasinačke kulture.
A Snapshot of Food Insecurity & Health Among: University of Waterloo Undergraduate Students
Authors: Andrade Lesley , Hussain Sanaa , Pepetone Alexandra , Qutub Mona , Kirkpatrick Sharon
Published: January 2025

There is no abstract for this submission.
The Artificial Intelligence Dilemma: Navigating Ethics in Healthcare
Authors: Mullaj Elen
Published: January 2025

The integration of Artificial Intelligence (AI) into healthcare represents a transformative shift towards more accurate and efficient patient care, highlighted by advancements in disease detection, treatment adherence, and patient interaction. However, this technological evolution introduces significant ethical dilemmas, including concerns over empathetic care provision, data security, and bias in clinical decision-making. This literature review critically examines these ethical challenges and proposes potential solutions to ensure AI's beneficial integration into healthcare without compromising patient well-being. The exploration into AI's capacity for empathetic care reveals its limitations to cognitive empathy, suggesting a complementary role to human providers rather than a replacement. Data privacy concerns underscore the imperative for secure handling and consent mechanisms in the utilization of patient information, amidst the risk of misuse by large corporations. Furthermore, the review addresses AI-induced biases, advocating for diverse data representation and algorithmic transparency to mitigate discrimination and enhance treatment efficacy across varied populations. While acknowledging the potential of AI to revolutionize healthcare, this paper advocates for a cautious and ethically informed approach to its adoption, emphasizing the need for comprehensive legislation, stakeholder engagement, and ongoing scrutiny to safeguard against the erosion of trust and equity in patient care.
Creating a Personal Learning Environment through Information Behavior Inspired by Teacher’s Feedback
Authors: Janiūnienė Erika , Stonkienė Marija , Šupa Maryja
Published: January 2025

Teacher’s feedback, accompanied by student self-reflection, promotes the integration of learning environments and the creation of a personal learning environment for students. The analysis of both pedagogical and technological discourses of personal learning environments draws attention to the importance of the student’s information behavior in the creation of a personal learning environment.
This study examines students’ information behavior, initiated by the teacher’s feedback. An exploratory study (survey, n=111) showed that the teacher’s feedback stimulates self-reflection among the participants and is associated with a clear personalization of some of the study participants’ learning needs. Teacher’s feedback stimulates information seeking. Information behavior inspired by teacher’s feedback builds their personalized learning environment through information seeking and creation of information/learning products. It has been pointed out that consistency of teacher’s feedback is important for information seeking and for making sense of and using information. Teacher’s feedback inspires cooperative information behavior. This demonstrates the importance of students’ social self-reliance, both in the sharing of feedback information and in learning, searching, selecting information resources, and creating information/learning products. At the same time, it demonstrates the objectives, the means of the social dimension of the participants’ personal learning environment. The study of the technological aspects of information behavior showed that technology is most often used for information seeking, information organization and social interaction. The study showed the interactive use of university and external technological platforms.
An Exclusively Urban Phenomenon? Radical Agrarianism in Political Practice of Interwar Fascism : A Case Study of Slovakia
Authors: Hruboň Anton , Ristveyová Katarína
Published: January 2025

Fascism is frequently considered to be a political movement associated with cities. The article attempts to contest this idea through a case study, which illustrates the agrarian-focused drive of fascism by profiling two fascist organisations in interwar Slovakia. It stresses agrarianism as a core factor of their political practice. The case study is based on an analysis of Rodobrana (1923–1929), a paramilitary organisation of Hlinka’s Slovak People’s Party, which became a significant pioneering fascist movement in Slovakia, and the National Fascist Community (1926–1938), the most notable political party representing nationwide Czechoslovak fascism. Even though both streams were written down in history as relatively unsuccessful cliques of cads, their palingenetic discourse, based on radicalised agrarian thought, helped create an atmosphere that resulted in the acceptance of the latter measures adopted by Hlinka’s Slovak People’s Party’s regime (confiscation of properties belonging to the “political parvenus”, Aryanisation of Jewish assets, agrarian reforms, and the programme of Slovak national socialism).
Relationship between the amount of blood transfusion and the amount of iron chelation with blood and salivary ureum levels in children with beta thalassemia major
Authors: Pradypta Putu Gyzca , Titien Indah , WM Putri Kusuma
Published: January 2025

Introduction: Patients with thalassemia experience a synthesis of one of the beta chains of the globin gene, resulting in reduced hemoglobin formation. Patients with beta-thalassemia major require routine transfusions and iron chelation. Both of these cause impaired kidney function. This study aims to determine the relationship between the amount of blood transfusion and the amount of iron chelation with blood urea and saliva levels in children with beta-thalassemia major.
Methods: An observational cross-sectional study was conducted at Moewardi Hospital, Solo using patients with beta-thalassemia major as subjects, taken by consecutive sampling from September to November 2018. The data on blood transfusion, iron chelation, and blood urea levels were obtained from medical records. Unstimulated saliva was taken in the morning. The urease method was used to assess the salivary urea levels and all data was analyzed using Pearson correlation analysis.
Result: The results showed the mean amount of transfusion was 71.9 ± 34.3, the amount of iron chelation 61.0 ± 32.1, blood urea levels 4.41 ± 1.1 mg / dL, and salivary urea levels 35.6 ± 12.5 mg / dL. Correlation analysis showed a positive correlation between the amount of blood transfusion and the amount of iron chelation with blood and saliva urea levels. There was also a positive correlation between blood urea and saliva levels.
Conclusion: It can be concluded that the amount of blood transfusion and iron chelation affects urea levels in blood and saliva in children with beta-thalassemia major. The close correlation between blood and saliva urea indicates that salivary urea can be used as an alternative assessment of blood urea.
Determinants of patient satisfaction after total knee arthroplasty (TKA): a literature review
Authors: Putera Anggi Dwi , Hasan Muhamad , Riyadli Muhammad , Fakhry Muhammad Nadlir
Published: January 2025

Link of Video Abstract: https://youtu.be/VANVlW_pP94
 
Background: The most common form of degenerative joint disease is osteoarthritis. Concomitant with the increased prevalence of osteoarthritis, the incidence of total knee arthroplasty (TKA) also rises. Total knee arthroplasty (TKA) is a surgical procedure for replacing an abnormal knee joint with artificial materials. Total knee arthroplasty (TKA) is a cost-effective orthopedic surgery with good patient outcomes. This literature review aimed to elaborate on the determinants of patient satisfaction after TKA surgery.
Methods: This literature review was carried out by searching studies in three online databases consisting of Google Scholar, PubMed, and Wiley Online Library using the keywords “total knee arthroplasty”, “total knee replacement”, “osteoarthritis”, “satisfaction”, and “determinants” to specify our study results. Appropriate studies were then carried out through a narrative synthesis analysis.
Results: The satisfaction of patients after two broad components determines TKA. Internal and external. The internal component consists of the patient's age, gender, personality, expectations, comorbidity, the severity of the disease, and other factors such as BMI, economic and educational class. While the external component consists of anesthesia and pain management, surgery technique, implant or prosthesis type, post-operative rehabilitation and length of hospital stay. Therefore, the surgical technique, including its indications, alternatives, prospective results, and risk of issues, must be fully discussed between doctors and patients to maintain patient satisfaction following TKA.
Conclusion: The determinant of patient satisfaction following TKA surgery can be classified into internal components (patient-related factor) and external components (surgery-related factor). Although important, patient satisfaction shouldn't be the determining factor for evaluating the efficacy of surgical treatments and patient care.
Development of novel wound dressing based collagen/chitosan/nigella sativa on blood leukocyte profile and malondialdehyde levels in incision wounds
Authors: Ary Andini  , Nastasya Nunki  , Ersalina Nidianti  , Devyana Dyah Wulandari  , Sharida Fakurazi
Published: January 2025

Introduction: Nigella sativa for wound dressing has never been developed already. It could be incorporated into collagen and chitosan as composite dressing to accelerate wound repair. This study aimed to analyze the effect of collagen/chitosan/Nigella sativa composite dressing for incision wound care in differential leukocyte count and serum malondialdehyde (MDA) levels.
Methods: Collagen/Chitosan/Nigella sativa composite dressing was synthesized by mixing collagen and chitosan solution with Nigella sativa oil in various concentrations, which were divided into four main groups such as N (1:1:0 w/w/w), IL (2:2:1 w/w/w), IM (1:1:1 w/w/w), and IH (1:1:2 w/w/w). Leukocyte profiles, including basophile, eosinophil, neutrophil stabs, neutrophil segments, lymphocytes, and monocytes, were observed using blood smear methods on the 3rd and 14th days. A serum malondialdehyde (MDA) assay was conducted using a UV-VIS spectrophotometer.
Results: Differential leukocyte count decreased from the 3rd and 14th days, except lymphocyte count, which continued higher on the 14th day. The serum MDA assay revealed decreased levels from the 3rd and 14th days.
Conclusion: Incision wound care using collagen/chitosan/Nigella sativa dressing could reduce the inflammation phase and accelerate the wound healing process.
Body mass index and total testosterone level in obese male pre-diabetic patients: correlation with homeostasis model assessment of insulin resistance
Authors: Decroli Eva , Aprilia Dinda , Kam Alexander , Rahmadi Afdol
Published: January 2025

Link of Video Abstract: https://www.youtube.com/watch?v=zABLxwmAXtA
 
Introduction: Men with comorbidities are typically more likely to have testosterone insufficiency. In this study, total testosterone levels in obese male pre-diabetic patients will be correlated with body mass index and a homeostasis model assessment of insulin resistance (HOMA-IR).
Methods: This investigation is a cross-sectional analytical observational study. Insulin resistance was measured by HOMA-IR. Enzyme link immunosorbent assay (ELISA) was used to measure the total testosterone levels. 35 obese male patients who were also pre-diabetic had these signs evaluated.
Results: In this study, 35 obese male individuals with a family history of type 2 diabetes mellitus and an average age of 31.91 were included (3.79). The total testosterone level was 328.72 (94.94), the mean BMI was 33.12 (4.11) kg/m2, the HOMA-IR was 3.64 (1.00), and testosterone levels were lowered (300 ng/dl) in 48% of the individuals. In male pre-diabetic individuals, there was a strong negative connection between BMI and Total Testosterone levels (r = -0.567, p=0.001). In male pre-diabetic patients, there was a significant negative connection between HOMA-IR and total testosterone levels (r = -0.671, p=0.001).
Conclusion: In pre-diabetic obese male patients, there was a strong inverse relationship between total testosterone level and BMI. In obese male pre-diabetic individuals, there is a substantial negative association between HOMA-IR and total testosterone level.
The association between blood culture findings and increased procalcitonin levels in burn patients at the burn unit of RSUD Dr. Soetomo Surabaya
Authors: Zakanito Marelno , Saputro Iswinarno Doso , Zarasade Lobredia
Published: January 2025

Link of Video Abstract: https://www.youtube.com/watch?v=ftHR9-tAQxs
 
Background: Normally, blood procalcitonin is generally undetectable in healthy individuals. However, blood procalcitonin levels can be detected in severe bacterial infections, especially sepsis. Blood culture is the gold standard for diagnosing sepsis; however, it takes 24-48 hours to obtain the results, making it difficult to administer antibiotics early.
Method: This is a cross-sectional observational retrospective analytic study. A total sampling method was used, where all burn patients who were treated at the Burns Unit at RSUD Dr. Soetomo Surabaya from 2020 to 2022 and met the inclusion criteria were enrolled if the data was complete. All burn patients treated at the Burn Unit of Dr. Soetomo Surabaya Hospital who underwent examination of blood procalcitonin levels and blood culture were included. Data collection was carried out by recording medical records. The data obtained from the research was entered into a table and then processed with SPSS 26 for Windows.
Result: There are a total of 84 patients, predominantly male (n=63; 75%). There were 79 patients with burns of more than 10% (94%). Out of 84 patients, 46 (54.8%) had bacteria or fungi in their blood culture, and 34 patients (40.5%) showed an increase in blood procalcitonin with levels of more than 2 ng/ml. There is an association between the presence of bacteria or fungi in blood culture and increased procalcitonin levels in the blood (p-value <0.05)
Conclusion: The most common bacteria found in blood cultures of burn patients in this study was gram-negative bacteria Acinetobacter baumannii. There is a significant relationship between the discovery of bacteria or fungi in blood culture and increasing blood levels of procalcitonin.
The profiles of mandibular fracture patients in the emergency ward of the head and neck surgery division in Dr. Soetomo General Hospital Indonesia
Authors: Rusdiansaputra Ferry , Wibowo Marjono Dwi
Published: January 2025

Link of Video Abstract: https://youtu.be/dT_k0C9UhI0
 
Background: Maxillofacial fracture is one of the most common injuries in trauma patients, especially in patients with traffic accident mechanisms. In this study, we aim to analyze the profile of patients with maxillofacial fractures, especially mandibular fractures, who came to tertiary hospitals.
Methods: Observational descriptive study to evaluate the profile of mandibular fracture patients who came to the Emergency Department of the Head and Neck Surgery Division of Dr. Soetomo General Hospital Surabaya in 2022. Data were analyzed using SPSS version 23.0 for Windows.
Results: Subjects were grouped according to age, sex, and mechanism of trauma. The most prevalent gender was male. The age group with the highest prevalence of accidents was 11-20 years (32.5%). Most maxillofacial traumas were caused by traffic accidents (92.5%). Associated trauma was found in 65% of subjects. Mandibular fractures tend to occur as part of multiple maxillofacial fractures compared to a single maxillofacial fracture, which is as much as 65%. The most common location of the fracture line in the mandible is the mandibular parasymphysis, which accounted for 33.3% of all samples. The most common mandibular fracture lines were 2 lines (47.5%).
Conclusion: Mandibular fractures are more likely to be part of multiple maxillofacial fractures than a single maxillofacial fracture and are often accompanied by concomitant trauma to other organs than a single trauma.
Multiple re-exploration due to excessive bleeding due to coagulopathy after aortic valve replacement in patients with chronic asymptomatic hepatitis B infection: A case report
Authors: Napitupulu Rindu Anggara Parulian , Soenarto Ratna Farida , Heriwardito Aldy
Published: January 2025

Link Of Video Abstract: https://youtu.be/RelpPxOynWw
 
Background: Postoperative bleeding following cardiac surgery represents a recognized and significant complication, particularly in patients with asymptomatic hepatitis B infection who have undergone open-heart procedures with a cardiopulmonary bypass machine (CPB). Patients requiring re-exploration due to bleeding face elevated mortality risks due to detrimental factors associated with the procedure, such as bleeding, transfusions, hypoperfusion resulting from cardiac tamponade or blood loss, multiple organ ischemia, and organ failure. The aim of this article is to discuss perioperative preparations specific to cases of patients with chronic hepatitis B undergoing open-heart surgery.
Case Presentation: This case study revolves around a 53-year-old Asian male who had been slated for aortic valve replacement. Transthoracic echocardiography (TTE) uncovered severe aortic regurgitation with vegetation at the non-coronary cusp (NCC) and right coronary cusp (RCC), accompanied by chamber dilatation. The patient was under Tenofovir therapy for his chronic yet asymptomatic hepatitis B infection. The surgical procedure utilized a cardiopulmonary bypass machine (CPB), but multiple re-explorations were necessitated due to excessive bleeding attributed to post-surgery coagulopathy.
Conclusion: Postoperative bleeding following cardiac surgery represents a widely recognized and serious complication, particularly in patients with asymptomatic hepatitis B infection who have undergone open-heart procedures with CPB. CPB has been extensively documented to stimulate the generation and release of various vasoactive substances and cytotoxic mediators, disrupting "rebalanced hemostasis" and leading to coagulopathy.
Interleukin-17 expression is associated with survival in pediatric osteosarcoma
Authors: Riza Muhammad , Salimo Harsono , Wasita Brian , Widyaningsih Vitri , Purwanto Bambang , Utomo Pamudji , Soestrisno Soestrisno , Hakim Fikar Arsyad , Zahidah Fairuz , Wayanshakty Janur
Published: January 2025

Link of Video Abstract: https://youtu.be/qXGE9z-UpDs
 
Background: Osteosarcoma is a cancerous tumor that develops from bone-forming mesenchymal cells. The cause of osteosarcoma appears to be multifaceted, and cytokine production is a potential causative factor. T helper 17 cells are responsible for producing the cytokine interleukin 17 (IL-17), and its association with cancer progression remains a subject of ongoing debate. This study aimed to analyze IL-17 expression before and after neoadjuvant chemotherapy and the relationships between prognostic factors and survival.
Methods: We investigated the expression of IL-17 in osteosarcoma tissues from 22 pediatric patients who underwent neoadjuvant chemotherapy. Histopathological and immunohistochemical methods were used to assess IL-17 expression prior to the patients undergoing neoadjuvant chemotherapy. IL-17 expression before chemotherapy was classified as low or high based on the median data. Survival was calculated using the Kaplan–Meier survival analysis with the log-rank test.
Result: The following characteristics were found to be associated with longer survival: male, age > 10 years old, distal location of tumor, low-grade tumor, and tumor with no metastasis; however, there were no statistically significant differences (p > 0.05). Binary logistic analysis showed that high expression of IL-17 based on the median data before neoadjuvant chemotherapy (>1.62%) were significantly associated with reduced survival (p = 0.010). The mean estimated overall duration of survival was 19.4 months (95% confidence interval (CI): 14.5-24.3) for low IL-17 expression and 14.0 months (95%CI: 8.3–19.7) for high IL-17 expression based on the median data. There was no statistically significant difference in the overall survival (p > 0.05).
Conclusion: High expression of IL-17 before neoadjuvant chemotherapy after neoadjuvant chemotherapy were associated with poor survival among pediatric osteosarcoma patients. These findings suggest that IL-17 is a potential prognostic biomarker for pediatric osteosarcoma.