bluuebunny/crossref_metadata_2025 huggingface dataset:
Longitudinal research on the dynamics and internal mechanism of female entrepreneurs’ passion
Authors: Fu Xiaorong , Ran Yaling , Xu Qian , Chu Tianshu
Published: November 2022

Based on Vallerand’s dualistic model of passion, this study theorizes and empirically examines the temporal dynamics of two types of entrepreneurial passion in female entrepreneurs, harmonious entrepreneurial passion (HmEP) and obsessive entrepreneurial passion (ObEP), and examines the mechanisms by which entrepreneurial effort0 and fear of failure influence the temporal dynamics of entrepreneurial passion. Using data collected from a three-wave, lagged survey of female entrepreneurs, we employed Mplus to build a latent growth model for entrepreneurial passion and built a cross-lag model of the relationship between entrepreneurial passion, entrepreneurial effort, and fear of failure. We found that female entrepreneurs’ HmEP and ObEP present different temporal dynamics. Furthermore, the temporal dynamics of HmEP are achieved through changes in entrepreneurial effort, whereas the temporal dynamics of ObEP are achieved through changes in current entrepreneurial effort and fear of failure in the next stage. Therefore, due to traditional gender stereotypes and varying motivations to engage in entrepreneurship, the two entrepreneurial passions have different dynamic evolution processes. Our results underscore the importance of effort and fear of failure in stimulating the dynamics of female entrepreneurial passion.
Integrative systemic and family therapy for social anxiety disorder: Manual and practice in a pilot randomized controlled trial (SOPHO-CBT/ST)
Authors: Hunger-Schoppe Christina , Schweitzer Jochen , Hilzinger Rebecca , Krempel Laura , Deußer Laura , Sander Anja , Bents Hinrich , Mander Johannes , Lieb Hans
Published: November 2022

Social anxiety disorders (SAD) are among the most prevalent mental disorders (lifetime prevalence: 7–12%), with high impact on the life of an affected social system and its individual social system members. We developed a manualized disorder-specific integrative systemic and family therapy (ISFT) for SAD, and evaluated its feasibility in a pilot randomized controlled trial (RCT). The ISFT is inspired by Helm Stierlin’s concept of related individuation developed during the early 1980s, which has since continued to be refined. It integrates solution-focused language, social network diagnostics, and genogram work, as well as resource- and problem orientation for both case conceptualization and therapy planning. Post-Milan symptom prescription to fluidize the presented symptoms is one of the core interventions in the ISFT. Theoretically, the IFST is grounded in radical constructivism and “Cybern-Ethics,” multi-directional partiality, and a both/and attitude toward a disorder-specific vs. non-disorder-specific therapy approach. SAD is understood from the viewpoint of social systems theory, especially in adaptation to a socio-psycho-biological explanatory model of social anxiety. In a prospective multicenter, assessor-blind pilot RCT, we included 38 clients with SAD (ICD F40.1; Liebowitz Social Anxiety Scale, LSAS-SR > 30): 18 patients participated in the ISFT, and 20 patients in Cognitive Behavioral Therapy (CBT; age:M = 36 years,SD = 14). Within-group, simple-effect intention-to-treat analyses showed significant reduction in social anxiety (LSAS-SR; ISFT:d = 1.67; CBT:d = 1.04), while intention-to-treat mixed-design ANOVA demonstrated the advantage of ISFT (d = 0.81). Per-protocol analyses supported these results. The remission rate based on blind diagnosticians’ ratings was good to satisfactory (Structured Clinical Interview, SCID; 78% in ST, 45% in CBT,p = 0.083); this has yet to be verified in a subsequent confirmatory RCT. The article will present the ISFT rationale and manual, including a special focus on multi-person settings, and the central findings from our pilot RCT.
Traumatic chain: Korean–American immigrants’ transgenerational language and racial trauma in Native Speaker
Authors: Ahmad Muhammad Sohail , Nawaz Shazmeen , Bukhari Zainab , Nadeem Mubashar , Hussain Rana Yassir
Published: November 2022

The premise of this study is to look at the intergenerational transferal of language and racial trauma of Asian immigrants in general and Korean–American immigrants in particular to a western country, the United States of America. This study investigates trauma from a psychological standpoint, based on Chang-Rae Lee’s novel Native Speaker. In describing a marker of citizenship, the novel’s title also points to who is the native language speaker and who is a native of a country, and why one who is not may be excluded. The Korean immigrants’ vulnerability to the English language and racial differences highlights their status as minority “others,” and they suffer from transgenerational trauma. As a result of transgenerational traumatic effects, Henry (the protagonist) has various traumatic side effects such as dysphasia, aphasia, and parasomnia and finally leaves no stone unturned to recuperate from trauma. The Trauma of the Unspeakable theory by Michelle Balaev is used in this article to show how trauma affects people’s minds.
Coping with weight stigma: Validation of the Persian brief coping responses inventory with Iranian adolescents sample
Authors: Kargari Padar Leila , Asgharnejad Farid Ali Asghar , Fathali Lavasani Fahimeh , Farahani Hojjatollah , Gharaei Banafsheh
Published: November 2022

Individuals who are overweight or obese encounter frequent weight-related stigma experiences, which are associated with negative health outcomes. In this regard, the Brief Coping Responses Inventory (BCRI) was developed as a measure of core coping responses to weight stigma, with 10 items loading on two subscales of reappraisal and Disengagement coping. The current study aimed to examine the psychometric properties of the Persian BCRI with 253 Iranian school-attending youth (Mage = 15.38, SD ± 0.50; 53% female) who had BMI score over 30. The results of the confirmatory factor analysis supported the originally proposed two-factor model (RMSEA = 0.028; CFI = 0.996; TLI = 0.994), which yielded acceptable internal consistency based on various reliability measures such as Cronbach’s alpha coefficients (0.79 and 0.88 for reappraisal and disengagement factors, respectively) and demonstrated the expected convergent and divergent associations with external correlates of interest (e.g., anxiety, depression, and body dissatisfaction scores). This study was also the first one worldwide to examine and report that the originally proposed two-factor model of the BCRI is invariant across gender groups, which allows for examining mean differences in BCRI scores across gender groups. Overall, our results indicated that the BCRI is a valid and reliable measure with a solid factor structure, which could be used to examine the coping reactions to weigh related stigma experiences among youth samples in Iran. Our results may encourage future studies on the psychometrics of the BCRI with other Iranian samples (e.g., university students, community, and clinical samples).
Association between the reactivity of local cerebral oxygen saturation after hypo-to-hypercapnic tests and delirium after abdominal surgery in older adults: A prospective study
Authors: Song Jie , Cheng Chen , Sheng Kui , Jiang Ling-Ling , Li Yun , Xia Xiao-Qiong , Hu Xian-Wen
Published: November 2022

Objective

This study aimed to investigate the correlation between changes in regional cerebral oxygen saturation (rSO2) and postoperative delirium in older adults undergoing major abdominal surgery.

Materials and methods

This prospective study enrolled older adults scheduled for elective major abdominal surgery at the Second Affiliated Hospital of Anhui Medical University from August 2021 to January 2022. The change in rSO2 from baseline was determined using the hypo-to-hypercapnic test. The main study outcome was the occurrence of postoperative delirium.

Results

A total of 101 participants were included for analysis, of whom 16 (15.8%) developed postoperative delirium. Compared with non-delirium participants, the mean arterial pressure and heart rate were not significantly different in the postoperative delirium group at T0, T1, T2, T3, T4, and T6 (all Pinteraction > 0.05), but the delirium group had lower pH, lower PaO2, and higher lactate levels at T4, T5, and T6 (all Pinteraction < 0.05). rSO2 at T0, T1, T2, T3, T4, and T6 was 69.0 (63.2–75.2), 70.7 ± 7.3, 68.2 ± 7.5, 72.1 ± 8.0, 69.9 ± 7.8, 67.4 ± 7.2, and 71.7 ± 8.1, respectively. The postoperative change in rSO2 during the hypercapnia test (TΔrSO2%) was 6.62 (5.31–9.36). Multivariable analysis showed that the Cumulative Illness Rating Scale (odd ratio, OR = 1.89, 95% confidence interval, CI: 1.10–3.25, P = 0.021), preoperative albumin levels (OR = 0.67, 95% CI: 0.48–0.94, P = 0.022), rSO2 at T4 (OR = 0.61, 95% CI: 0.41–0.89, P = 0.010), and postoperative TΔrSO2% (OR = 0.80, 95% CI: 0.66–0.98, P = 0.028) were independently associated with postoperative delirium in older adults undergoing elective abdominal surgery.

Conclusion

The rSO2 measured at T4 and postoperative TΔrSO2% were independently associated with postoperative delirium in older adults undergoing elective abdominal surgery.
Healthcare professionals' perception and satisfaction with mental health tele-medicine during the COVID-19 outbreak: A real-world experience in telepsychiatry
Authors: Roncero Carlos , Remon-Gallo Diego , Casado-Espada Nerea , Aguilar Lourdes , Gamonal-Limcaoco Sinta , Gallego María Teresa , Bote Berta , Montejo Angel Luis , Buch-Vicent Barbara
Published: November 2022

Background

The use of telemedicine is increasingly being implemented, showing numerous benefits over other methods. A good example of this is the use of telemedicine following the breakdown caused by the COVID-19 pandemic. Previous experiences with telemedicine (TM) have not been significantly explored in relation to the professionals' own perspectives.

Objective

Identify and explore the perceptions and interests of mental health professionals who have performed TM during the period of pandemia.

Methods

A questionnaire on mental health professionals' perceptions of and satisfaction of TM, the Font Roja Work Satisfaction Questionnaire, was adapted and used. Data collected included 112 Psychiatric Service professionals who conducted TM in March 2020, after the country had been under lockdown for 10 weeks. Over 12.000 medical consultations were carried out by the phone, showing an overwhelming response to this method.

Results

High levels of satisfaction were recorded amongst professionals. TM would function as a complement to the traditional system of face-to-face visits (n-112, f-109, 96.5%). Only 9.7% (f-11) believed that digital or virtual interventions would completely replace face-to-face visits. 60.8% did not consider this monotonous work. The older the health workers were, the more satisfied they felt during their follow-up telephone consultation. The greater the previous experience, the more satisfaction was shown. There were gender differences: female mental health workers reported a greater level of comfort.

Conclusion

TM can be implemented with less effort, but it requires time, methods, and resources to be managed. Satisfaction among professionals is high, especially among those with more clinical experience. Patient satisfaction must be contrasted against this.
Adaptation among aged care and disability service providers in response to the COVID-19 pandemic: Lessons for the future
Authors: Seivwright Ami , Kaleveld Lisette , Meltzer Ariella , Atkins Mariana , Varadharajan Meera , Campbell Perri , Callis Zoe , Wilson Erin
Published: November 2022

Aged care and disability service organizations are critical infrastructure. However, in 2020, restrictions were introduced to reduce the infection risk of the coronavirus disease 2019 (COVID-19), and these organizations needed to quickly devise COVID-safe ways of working to continue to meet the needs of their clients. To investigate how these organizations adapted their service delivery and which innovations they felt were worthwhile for sustaining beyond the COVID-19 pandemic, interviews were undertaken with representatives from 26 aged care and disability service organizations across three states in Australia (Western Australia, New South Wales, and Victoria). Findings revealed that organizations adapted their practices across three key innovation areas: (1) developing new approaches or expanding existing services, particularly around food provision, social connection, information dissemination, and technology support; (2) modifying the mode of service delivery, through safe in-person contact or offering alternative online services; and (3) reducing bureaucracy and introducing remote working. A common theme across all service innovations was the strong focus on providing clients and staff with choice and control. Moving forward, many organizations wanted to integrate and maintain these innovations, as they were associated with additional benefits such as increased client health and safety, service flexibility, and sufficient human resources to serve clients. However, continued maintenance of some initiatives require additional resourcing. The continuation of COVID-19 pandemic adaptations and, indeed, ongoing innovation, would therefore be facilitated by greater flexibility of funding to allow organizations and their clients to determine the service types and modes that best meet their needs. Further, these innovations have implications for sector-wide best practice.
Core functions and forms of Bright IDEAS: A multi-methods evaluation of the adoption of an evidence-based psychosocial training program through iterative adaptation
Authors: McNeal Demetria M. , Sahler Olle Jane Z. , Noll Robert B. , Fairclough Diane L. , Voll Megan E. , Bhat Shubha , Morrato Elaine H.
Published: November 2022

Background

Despite efforts to widely disseminate interventions designed to increase access to quality supportive care to pediatric cancer patients and their families, many of these interventions fail to meet expectations once deployed in real-life clinical settings. This study identifies the functions and forms of Bright IDEAS: Problem-Solving Skills Training, an evidence based psychosocial intervention for caregivers of children recently diagnosed with cancer, to identify pragmatic program adaptations in its real-world clinical implementation. We compare intervention adoption before and after adaptations to the Bright IDEAS training program as part of a national training program designed to disseminate the intervention.

Methods

209 pediatric psychosocial oncology practitioners representing 134 unique institutions were trained during 10 in-person 8-hour workshops (2015–2019). Functions and forms of Bright IDEAS were identified, and adaptations made to the training agenda and curriculum based on practitioner feedback following implementation in local institutions. Mixed method evaluation included longitudinal surveys at 6- and 12-months post training; and qualitative interviews among a subgroup of practitioners (N = 47) to understand and compare perspectives on intervention adoption and barriers to implementation before and after adaptations to the Bright IDEAS training program. The RE-AIM framework was used to guide dissemination evaluation.

Results

A total of four adaptations were tailored to the identified forms of the intervention: case studies; pre-training reading materials; training videos; and letters of institutional support from primary supervisor. Pre- and post-training adaptations to the Bright IDEAS training program were mapped to RE-AIM constructs. Quantitative findings demonstrate that adaptations appeared to improve adoption and usage overall.

Conclusion

This study provides insight into how contextual factors influence psychosocial practitioners' capacity to adopt, implement, and maintain Bright IDEAS in the clinical setting. This study demonstrates the use of real-time stakeholder feedback to guide intervention translation from research to practice settings.
Analysis of the available funds supporting marine activities in some key European Mediterranean countries
Authors: Gambino Monica , Accadia Paolo , Costantini Marco , Gomei Marina , Malvarosa Loretta , Sabatella Evelina Carmen , Sabatella Rosaria Felicita
Published: November 2022

The study presented in this article analyzed qualitative and quantitative data on the performance of the European Maritime and Fisheries Fund (EMFF) based on the information reported in the European Union (EU) List of Operations updated to December 2020. Each EMFF measure and type of financial support were divided into three broad categories of subsidies according to their main objectives and scope: capacity enhancing, beneficial, or ambiguous. Capacity enhancing is defined as funds that could incentive overcapacity or overfishing. Beneficial refers to subsidies that have a positive impact on fish stocks and the environment. Ambiguous subsidies correspond to funds that may lead to positive or negative impacts on the environment depending on how they are designed and implemented. The assessment revealed the asymmetric distribution of EMFF resources in the Mediterranean region. In the six member states investigated, EMFF support is concentrated on a limited number of more easily accessible measures from an administrative and financial point of view. Most of the allocated funds are classified as capacity enhancing; other frequently used measures are in the ambiguous category. Small-scale vessels using static gear and accounting for the largest part of the Mediterranean fleets received a negligible share of specific funds for promoting environmentally sustainable fisheries. Most investments are concentrated on larger trawlers to support the temporary cessation of fishing activities and scrapping operations. Further qualitative analysis based on the findings and recommendations of previous reports evaluating the use of EMFF as well as interviews with beneficiaries highlighted that complex administrative procedures and legal uncertainty in the interpretations of some articles of the EMFF regulations are the main reasons for the asymmetric performance of the EMFF measures. The dispersion of responsibilities among European, national and regional authorities, and an evident lack of coordination among them are the main shortcomings that were identified. The limited use of advance payments, the lack of capacity, and technical assistance and obstacles to accessing financial instruments have penalized most of the projects that are focused on innovation, diversification, and environmental sustainability.
A comprehensive review on advances in storage pest management: Current scenario and future prospects
Authors: Guru P. N. , Mridula D. , Dukare Ajinath Shridhar , Ghodki Bhupendra M. , Paschapur Amit Umesh , Samal Ipsita , Nikhil Raj M. , Padala Vinod Kumar , Rajashekhar Mandla , Subbanna Avupati R. N. S.
Published: November 2022

Modernization of the agricultural production system led to a significant increase in annual food production intended to meet the ever-growing consumer demand. In many countries, most of the food grains produced is stored for contingency and regular supply. These stored grains, in general, are directly or indirectly infested by insects, resulting in severe grain damages and storage losses, thus, causing a threat to food safety and security. Although a variety of insect management options, such as physical, mechanical, biological, and chemical methods, are available, fumigation has been practiced for decades in storage. However, opportunities for fumigation are narrowing after the phase-out of methyl bromide. Besides, safe food and health concerns paved the path for green chemistry and non-chemical management practices. This review includes the list of stored-grain insects and their detection methods. The different management strategies such as the modern storage structures (hermetic and low-pressure storages), modified or controlled storage atmosphere, application of ozone as fumigant, irradiation, and physical options are presented. Further, the details on sustainable biological options, such as semiochemicals, natural enemies, biopesticides, and entomopathogenic nematodes, are supplemented. The use of inert dusts as grain protectant and in combination with the biological entity is included. Studies on alternative fumigants', novel management options, such as molecular biology tools (RNAi and CRISPR) and nanotechnology in stored grain protection, are also highlighted. This review helps the reader to understand the overall factors affecting grain storage and the different options to manage the insects causing storage losses.
Culture and characterization of canine and feline corneal epithelial organoids: A new tool for the study and treatment of corneal diseases
Authors: Bedos Leila , Wickham Hannah , Gabriel Vojtech , Zdyrski Christopher , Allbaugh Rachel A. , Sahoo Dipak Kumar , Sebbag Lionel , Mochel Jonathan P. , Allenspach Karin
Published: November 2022

In this study, we isolated and cultured canine and feline 3D corneal organoids. Samples derived from corneal limbal epithelium from one canine and one feline patient were obtained by enucleation after euthanasia. Stem cell isolation and organoid culture were performed by culturing organoids in Matrigel. Organoids were subsequently embedded in paraffin for further characterization. The expression of key corneal epithelial and stromal cell markers in canine and feline organoids was evaluated at the mRNA level by RNA-ISH and at the protein level by immunofluorescence (IF) and immunohistochemistry (IHC), while histochemical analysis was performed on both tissues and organoids using periodic-acid Schiff (PAS), Sirius Red, Gomori's Trichrome, and Colloidal Iron stains. IF showed consistent expression of AQP1 within canine and feline organoids and tissues. P63 was present in canine tissues, canine organoids, and feline tissues, but not in feline organoids. Results from IHC staining further confirmed the primarily epithelial origin of the organoids. Canine and feline 3D corneal organoids can successfully be cultured and maintained and express epithelial and stem cell progenitor markers typical of the cornea. This novel in vitro model can be used in veterinary ophthalmology disease modeling, corneal drug testing, and regenerative medicine.
Barriers to mental health help-seeking in veterinary professionals working in Australia and New Zealand: A preliminary cross-sectional analysis
Authors: Connolly Caitlin Elizabeth , Norris Kimberley , Dawkins Sarah , Martin Angela
Published: November 2022

Despite higher reported rates of mental ill-health than the general population, professionals working in the animal care industry have low reported rates of help-seeking behavior. Potential factors involved in veterinary professionals' reluctance to seek help include stigma toward mental ill-health, practical barriers to accessing supports, and a cultural normalization of symptoms in the industry. This preliminary study sought to explore these factors in a sample of veterinarians, veterinary nurses, and veterinary technicians and examine effects of gender, years' experience, and practice location. A total of 408 veterinary professionals working in Australia and New Zealand completed an online survey between June and December 2021 measuring perceived stigma, practical barriers to mental health help-seeking, perceptions of normalized psychopathology and sickness presenteeism. Results indicated moderate levels of both perceived stigma and barriers to mental health help-seeking. Interestingly, psycho/pathology (e.g., burnout, fatigue, and sickness presenteeism) was perceived to be a normalized aspect of the profession by majority of respondents. Although no effect of gender or geographic location were observed, stage of career did have an effect on findings. Early career veterinary professionals were identified as more vulnerable to perceived stigma and barriers to care. The practical and research implications of the findings are discussed and include the need for mental health to be more centrally incorporated into the veterinary curriculum and professional development. Also discussed is an agenda for future research aimed at improving the mental health and wellbeing of professionals working in the animal care industry.
Application of a Posttreatment to Improve the Viability and Antifungal Activity of Trichoderma asperellum Biomass Obtained in a Bioreactor during Submerged Cultivation
Authors: Senkovs Maris , Dzierkale Marija Tereze , Rimkus Alina , Grigs Oskars , Nikolajeva Vizma
Published: November 2022

T. asperellum MSCL 309 was used in the study. T. asperellum was grown in the stirred bioreactor under submerged cultivation. The resulting biomass was filtered to obtain a thick biomass. The viability and antifungal activity of T. asperellum biomass samples were determined simultaneously by studying the colonization of the malt extract agar medium surface and its competitiveness with the plant pathogenic fungus Fusarium graminearum using in vitro dual culture experiments. Treatment with starch, alone or in combination with copper (II) sulphate and/or hydrochloric acid did not significantly affect fungal viability compared to control. An important factor in maintaining viability was the addition of hydrochloric acid, which significantly increased the storage life of biomass. In all post-treatments, F. graminearum was overgrown with T. asperellum in seven days, and accordingly, the larger the area occupied by T. asperellum, the smaller the area of F. graminearum colonization. Viability and antifungal activity of T. asperellum persisted throughout the experiment, at least for eight weeks. All the post-treatment methods we studied improved the viability and antifungal activity of Trichoderma, at least in terms of the area of the colonized surface. For the development of long-term viable and active T. asperellum preparations, we recommend the use of acidification of T. asperellum biomass obtained by submerged fermentation.
Fossil Fruits of Ceratophyllum from the Upper Eocene and Miocene of South China
Authors: Xu Shenglan , Song Hanzhang , Xiang Helanlin , Liu Weiqiu , Quan Cheng , Jin Jianhua
Published: November 2022

Ceratophyllum L. is a cosmopolitan genus of perennial aquatic herbs that occur in quiet freshwaters. Fossils of this genus have been widely reported from the Northern Hemisphere, most of them occurring in the temperate zone. Here, we describe two species of fossil fruits discovered from subtropical areas of China. The fossil fruit discovered from the upper Eocene Huangniuling Formation of the Maoming Basin is designated as C. cf. muricatum Chamisso, and fruits discovered from the Miocene Erzitang Formation of the Guiping Basin are assigned to the extant species C. demersum L. The discovery of these two fossil species indicates that Ceratophyllum had spread to South China by the late Eocene and their distribution expanded in subtropical China during the Miocene.
Beneficial Effect of Paeonol on Antibiotic-Associated Inflammatory Response in Mice with Diarrhea
Authors: Kang Bohyung , Park Do Hwi , Lee Myong Jin , Jeon Chan-Yong , Kang Ki Sung , Choi You-Kyung
Published: November 2022

Diarrhea is a common adverse effect of antibiotics particularly that acts on anaerobes. Moutan Radicis Cortex (MRC) is an herbal medicine used for its anti-inflammatory and antibacterial actions. The purpose of this study was to analyze the active components of MRC to determine their effect on antibiotic-associated diarrhea (AAD) and anti-inflammatory effects. Of the various components of MRC, seven compounds (gallic acid, oxypaeoniflorin, paeoniflorin, ethyl gallate, benzoic acid, benzoylpaeoniflorin, paeonol) were identified and assessed for anti-inflammation effects. Paeonol was found to effectively reduce nitric oxide production and levels of IL-6 and TNF-α in a concentration-dependent manner. Paeonol also effectively reduced the mRNA expression level of IL-6, IL-1β, and TNF-α. Western blotting analysis confirmed the reduction of COX-2 and NF-κB levels; p-p38 MAPK levels increased in the presence of a low concentration (25 μM) of paeonol but decreased in the presence of a high concentration (50 μM). In the mouse model of lincomycin-induced AAD, all experimental groups treated with paeonol (25, 50, and 100 mg/kg concentrations) showed diminished diarrhea status scores. Finally, the expression levels of TNF-α and IL-4 were reduced compared with those in the control group. Therefore, paeonol may have active compounds of MRC to alleviate the diarrhea symptoms of AAD and reduce inflammatory mediators. Other components of the MRC extract could contribute to its known anti-inflammatory and antibacterial activity and should be tested for their possible activity.
Influence of Classroom Colour Environment on College Students’ Emotions during Campus Lockdown in the COVID-19 Post-Pandemic Era—A Case Study in Harbin, China
Authors: Tao Weiyi , Wu Yue , Li Weifeng , Liu Fangfang
Published: November 2022

Campus lockdown during COVID-19 and the post-pandemic era has had a huge negative effect on college students. As a vital part of interior teaching spaces, colour deeply influences college students’ mental health and can be used for healing. Nevertheless, research on this topic has been limited. Based on colour psychology and colour therapy, this paper discusses the relationship between interior teaching space colours (hue and brightness) and emotions among college students. The HAD scale and questionnaire survey method were used. It was concluded that: (1) Anxiety and depression were prominent among the college student population during the quarantine of the university due to the epidemic. (2) Warm colours have an advantage over both cold and neutral colours in creating pleasure, relaxation, and mental attention, with the second in line being the cold and the last being the neutral. Warm colours make it pleasant for individuals while cold colours boost attention. (3) When subjects have higher values of anxiety and depression, they are less satisfied with the colour of the teaching space. (4) In most cases, there is no significant difference in the colour preference of teaching spaces across the gender, grade, and major groups, with females having a higher preference for warm high-brightness classrooms than males. These findings provide crucial ideas for future interior teaching space design and enrich the theories in colour psychology.
Inhibition of Glucose Uptake Blocks Proliferation but Not Cytotoxic Activity of NK Cells
Authors: Picard Lea Katharina , Littwitz-Salomon Elisabeth , Waldmann Herbert , Watzl Carsten
Published: November 2022

Tumor cells often have very high energy demands. Inhibition of glucose uptake is therefore a possible approach to limit the proliferation and survival of transformed cells. However, immune cells also require energy to initiate and to maintain anti-tumor immune reactions. Here, we investigate the effect of Glutor, an inhibitor of glucose transporters, on the function of human Natural Killer (NK) cells, which are important for the immunosurveillance of cancer. Glutor treatment effectively inhibits glycolysis in NK cells. However, acute treatment with the inhibitor has no effect on NK cell effector functions. Prolonged inhibition of glucose uptake by Glutor prevents the proliferation of NK cells, increases their pro-inflammatory regulatory function and reduces the stimulation-dependent production of IFN-γ. Interestingly, even after prolonged Glutor treatment NK cell cytotoxicity and serial killing activity were still intact, demonstrating that cytotoxic NK cell effector functions are remarkably robust against metabolic disturbances.
Interfacial Microstructure and Mechanical Properties of Pressureless Sintered SiC Ceramic and Stainless Steel Joints Brazed by AgCu/AgCuTi Alloy
Authors: Ma Qiang , Li Shengguo , Chen Yongwei , Pu Juan , He Peng
Published: November 2022

A high-quality joint of pressureless sintered SiC ceramic (PS-SiC) and stainless steel brazed by AgCu/AgCuTi brazing alloy was realized. The effects of brazing temperature and holding time on the interfacial microstructure and mechanical properties of PS-SiC-stainless steel were analyzed. During brazing, Fe and Cr diffused into a brazing seam, and the typical interfacial microstructure of joints brazed at 890 °C for 15 min was stainless steel/Cr5Si3 + FeSi2 + Ag(s,s)/Cr5Si3 + FeSi2 + Ag(s,s) + Cu(s,s) + TiSi2 + TiC/FeSi2 + Ag(s,s) + Cu(s,s) + TiSi2/Ag(s,s) + Cu(s,s) + SiC/PS-SiC ceramic. Cu-Fe system improved the toughness of the joint, and the shear strength of the joint increased to ~67 MPa. With increasing brazing temperature and holding time, the element Fe continued diffusing into the brazing seam, and the uniformity of Cu-Fe system became worse. Then Cu(s,s) infiltrated into the surface layer of PS-SiC ceramic and FeSi2 brittle phase gathered in the brazing seam. Then, the brittleness of the joint increased and the shear strength of the joint decreased.
Rotationally Adjustable Hyperthermia Applicators: A Computational Comparative Study of Circular and Linear Array Applicators
Authors: Yildiz Gulsah , Yilmaz Tuba , Akduman Ibrahim
Published: November 2022

Microwave breast hyperthermia (MH) aims to increase the temperature at the tumor location with minimal change in the healthy tissue. To this end, the specific absorption rate (SAR) inside the breast is optimized. The choice of the MH applicator design is important for a superior energy focus on the target. Although hyperthermia treatment planning (HTP) changes for every patient, the MH applicator is required to be effective for different breast models and tumor types. The linear applicator (LA) is one of the previously proposed applicator designs with linearly arranged antennas; however, it suffers from low focusing ability in certain breast regions due to its unsymmetrical geometrical features. In this paper, we propose to radially adjust the LA to obtain alternative excitation schemes without actually changing the applicator. Antipodal Vivaldi antennas were utilized, and the antenna excitations were optimized with particle swarm optimization (PSO). The comparison of the rotated and the fixed linear applicator, between 12-antenna circular and linear applicators, and finally, between a 24-antenna circular applicator are provided. Within the 12 rotation angles and two target locations that were analyzed, the 135° axially rotated linear applicator gave a 35% to 84% higher target-to-breast SAR ratio (TBRS) and a 21% to 28% higher target-to-breast temperature ratio (TBRT) than the fixed linear applicator. For the deep-seated target, the 135° rotated linear applicator had an 80% higher TBRS and a 59% higher TBRT than the 12-antenna circular applicator, while the results were comparable to the 24-antenna circular applicator.
A Machine Learning Challenge: Detection of Cardiac Amyloidosis Based on Bi-Atrial and Right Ventricular Strain and Cardiac Function
Authors: Eckstein Jan , Moghadasi Negin , Körperich Hermann , Weise Valdés Elena , Sciacca Vanessa , Paluszkiewicz Lech , Burchert Wolfgang , Piran Misagh
Published: November 2022

Background: This study challenges state-of-the-art cardiac amyloidosis (CA) diagnostics by feeding multi-chamber strain and cardiac function into supervised machine (SVM) learning algorithms. Methods: Forty-three CA (32 males; 79 years (IQR 71; 85)), 20 patients with hypertrophic cardiomyopathy (HCM, 10 males; 63.9 years (±7.4)) and 44 healthy controls (CTRL, 23 males; 56.3 years (IQR 52.5; 62.9)) received cardiovascular magnetic resonance imaging. Left atrial, right atrial and right ventricular strain parameters and cardiac function generated a 41-feature matrix for decision tree (DT), k-nearest neighbor (KNN), SVM linear and SVM radial basis function (RBF) kernel algorithm processing. A 10-feature principal component analysis (PCA) was conducted using SVM linear and RBF. Results: Forty-one features resulted in diagnostic accuracies of 87.9% (AUC = 0.960) for SVM linear, 90.9% (0.996; Precision = 94%; Sensitivity = 100%; F1-Score = 97%) using RBF kernel, 84.9% (0.970) for KNN, and 78.8% (0.787) for DT. The 10-feature PCA achieved 78.9% (0.962) via linear SVM and 81.8% (0.996) via RBF SVM. Explained variance presented bi-atrial longitudinal strain and left and right atrial ejection fraction as valuable CA predictors. Conclusion: SVM RBF kernel achieved competitive diagnostic accuracies under supervised conditions. Machine learning of multi-chamber cardiac strain and function may offer novel perspectives for non-contrast clinical decision-support systems in CA diagnostics.
Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial
Authors: Barajas-Torres Guadalupe Carolina , Klünder-Klünder Miguel , Garduño-Espinosa Juan , Parra-Ortega Israel , Franco-Hernández María Isabel , Miranda-Lora América Liliana
Published: November 2022

Sugary soft drinks modify salivary pH and favor bacterial proliferation and are associated with the development of caries. Information on the effects of consuming carbonated drinks without sucrose is limited. Methods: In this crossover clinical trial, salivary and dental biofilm pH were determined at 0, 5, 10, 15, 30, 45, and 60 min after the participants (n = 18) ingested a soft drink with sucrose, a soft drink with aspartame/acesulfame K, carbonated water, and plain water on different days. Dental biofilm cultures were conducted at 0- and 120-min. Results: Salivary pH decreased significantly after ingestion of the sucrose-containing soft drink when compared with the other types of beverages (median difference, −0.3–−0.4, p ≤ 0.05), and the greatest difference was found with mineral water. A greater bacterial proliferation (Colony Forming Units [CFU]) was observed after ingestion of the drink with sucrose (↑310 × 103 CFU, p ≤ 0.01), followed by the drink with aspartame/acesulfame K (↑160 × 103 CFU, p ≤ 0.01) and carbonated water (↑60 × 103 CFU, p ≤ 0.05). No significant changes in bacterial proliferation were observed after the consumption of natural water. Conclusions: Ingestion of sucrose-containing soft drinks favors the acidification of salivary pH and the bacterial proliferation of dental biofilm. Although to a lesser extent, soft drinks containing aspartame/acesulfame K also favor bacterial proliferation.
Investigation of Changes in Spermatozoon Characteristics, Chromatin Structure, and Antioxidant/Oxidant Parameters after Freeze-Thawing of Hesperidin (Vitamin P) Doses Added to Ram Semen
Authors: Yeni Deniz , Güngör Şükrü , Avdatek Fatih , Gülhan Mehmet Fuat , Olğaç Kemal Tuna , İnanç Muhammed Enes , Denk Barış , Taşdemir Umut
Published: November 2022

We conducted this study to determine the potential cryopreservative effects of different hesperidin (vitamin P; H) doses on ram semen after freeze-thawing. Semen samples were obtained from Sönmez rams using an artificial vagina. The samples were divided into six groups: control, 10, 50, 100, 250, and 500 µg/mL H (C, H10, H50, H100, H250, and H500, respectively). At the end of the study, sperm motility and kinetic parameters, acrosome integrity (AI), mitochondrial membrane potential (MMP), viability, lipid peroxidation levels (LPL), chromatin damage, oxidant parameters, and antioxidant parameters were assayed. None of the doses of H added to the semen extender showed any enhancing effects on progressive motility compared to C (p > 0.05). In fact, H500 had negative effects (p < 0.05). Moreover, AI was the highest at the H10 dose, while LPL values were the lowest at the same dose (p < 0.05). The doses of H10 and H50 added to the Tris extender medium showed positive effects on sperm cell chromatin damage. Consequently, we can say that H doses used in this study are not effective on semen progressive motility, but the H10 dose is effective on AI and chromatin damage by reducing LPL.
Temperature Rise Calculation of Magnetic Core Considering the Temperature Effect of Magnetic Properties in an Electrical Steel Sheet
Authors: Wang Zhen , Xu Kai , Du Yufeng
Published: November 2022

The magnetic properties of electrical steel sheets are affected by magnetization patterns, working temperature, and external pressure. In order to study the temperature effect of electrical steel sheets on the temperature rise of a transformer core, in this paper, based on the magnetic property test system of an electrical steel sheet, the permeability and loss of a 50AW600 grain non-oriented electrical steel sheet and a 30ZH120 grain oriented electrical steel sheet under different temperatures and excited frequencies were measured, and the influence of temperature on the properties of the material was analyzed. A magneto-thermal iterative coupling method considering the temperature effects of magnetic properties in the electrical steel sheet was investigated. Based on the above measurement data and iterative coupling method, the temperature distribution of the core of a 500-kV power transformer was simulated and analyzed, and compared with the simulation results of the traditional coupling method without considering the temperature effect of the electrical steel sheet. Magneto-thermal coupling simulation under no-load operation is a symmetrical problem. It was found that the temperature of the hottest spot of the transformer core calculated by the magneto-thermal iteration method proposed in this paper was significantly reduced, the temperature of the hottest spot on the core column was about 45 °C, and the temperature of the hottest spot on the upper and lower yoke was about 39 °C, which provides an effective simulation method for accurately calculating the temperature rise distribution of electrical products such as transformers.
Mercadotecnia en redes sociales de los restaurantes de cocina fusión más importantes de Quito
Authors: Jarrín Gallegos Diego
Published: November 2022

Los restaurantes requieren tener presencia en plataformas especializadas y redes sociales para hacer visible su oferta de servicio y captar la atención de su audiencia. En este contexto, el objetivo fue analizar la aplicación de las redes sociales como herramienta de mercadeo de los restaurantes de cocina fusión más importante de Quito según la plataforma turística Tripadvisor. Se determinaron las redes sociales más utilizadas por estos negocios, para posteriormente calcular y describir el engagement que obtuvieron en los últimos meses de 2020 en las dos redes sociales de mayor uso, y comprobar si la utilización de la publicidad de contenidos influyó en esta métrica. En Instagram, 58.82% de los negocios obtiene un engagement igual o superior a 4%; mientras que, en Facebook 26.47% obtuvieron un engagement igual o superior a 1%. Se evidenció que un número representativo de los 34 restaurantes de este estudio, registraron un porcentaje apropiado de engagement.
Les lieux de culte mithriaques face aux chrétiens dans la Rome tardo-antique
Authors: Mahieu Vincent
Published: November 2022

The issue of the Late Antique Roman Mithraism’s topographical network and the impact of the spreading of Christianity on these realities has long been an object of interest. In particular, this took place in the context of the– sometimes highly ideologically laden – investigation of the link between this growing religion and the “ Mysteries of Mithra” – to borrow the title of F. Cumont’s work. Despite the paradigmatic shifts in historiography and the fact that new, mainly archeological, data emerged during the last decades, the debate isn’t closed. An in-depth and dispassionate study is required. After a preliminary step involving the compilation of the Mithraic places of worship attested in the fourth-and fifth century Rome and the sharing of some findings drawn from it, this paper firstly proposes a series of considerations on the argument of a competition with the Church network. This is followed by a meticulous examination of the case of three mithraea (S. Clemente, S. Prisca and Castra Peregrinorum/ S. Stefano in Rotondo) whose end is regularly related to an intervention of Christians. The inquiry demonstrates that a competitive strategy in the churches settlement cannot be inferred – likenesses in the dynamics of both worships being possible explanatory factors – and that the data related to the three mithraea do not allow to favour the option of a Christian action, and drafts an innovative hypothesis (the “ritual closure”) in order to explain the material ending of these mithraea.
Diaries of Women in Captivity. The Internment of German and Austrian Civilians during the First World War as Depicted in the Testimonies of Gertrud Köbner, Helene Schaarschmidt and Helene Fürnkranz
Authors: Leclerc Hélène
Published: November 2022

Durant la Première Guerre mondiale, la France, comme d’autres belligérants, a interné les populations civiles ressortissantes des pays en guerre contre elle. L’un de ces camps d’internement français fut le couvent de Garaison (Hautes-Pyrénées), destiné plus spécifiquement à accueillir des familles, des femmes et des enfants. Dès 1915, après leur rapatriement en Allemagne ou en Suisse, trois femmes internées à Garaison (deux Allemandes, Gertrud Köbner et Helene Schaarschmidt, et une Autrichienne, Helene Fürnkranz) publièrent chacune un témoignage de cette expérience sous la forme de journaux-récits qui constituent une formidable source documentaire pour l’historien. Cet article propose une analyse comparée de ces trois textes et examine les caractéristiques du genre diarique, sa construction, l’intérêt de ce type de documents et les spécificités du journal, notamment féminin, en temps de guerre.
Vox Populi. Listening and Witnessing in German-Jewish War Diaries Written During the Third Reich
Authors: Augustyns Annelies
Published: November 2022

Times of crisis, such as war, which are characterized by drastic changes and fractures in daily life, call for reflection and explanation. The diary is a popular genre in this respect and is even described as “ the most appropriate written form in times of crisis”. (Nebel : 1948, p. 6) Not only reflecting, but also witnessing becomes highly important in the context of conflict and war. Diary authors endeavor to collect what seem at first sight to be unimportant details to record what has been said, what (rumors) circulated in their time, etc. These have significant value because they reflect the mood prevailing in the city and express the opinion of the population at that time – the so-called “ vox populi”. Diaries therefore represent a micrological archive of daily life which will be scrutinized by a close reading of German-Jewish war diaries written during the Third Reich. The focus will be on diary entries from Willy Cohn and Walter Tausk from Breslau that start from the beginning of the Second World War (September 1939) and run to the day of their deportation in November 1941. The analysis in the first part will revolve around three main topics : the opinions of ordinary people during war, the availability of information combined with criticism of the newspapers, and the consciousness (or not) of the fate of the Jewish citizens. The second part will reflected on the question of the genre of the diary and whether the diaries discussed here can be seen as war diaries.