bluuebunny/crossref_metadata_2025 huggingface dataset:
Choroid plexus APP regulates adult brain proliferation and animal behavior
Authors: Arnaud Karen , Oliveira Moreira Vanessa , Vincent Jean , Dallerac Glenn , Dubreuil Chantal , Dupont Edmond , Richter Max , Müller Ulrike C , Rondi-Reig Laure , Prochiantz Alain , Di Nardo Ariel A
Published: September 2021

Elevated amyloid precursor protein (APP) expression in the choroid plexus suggests an important role for extracellular APP metabolites such as sAPPα in cerebrospinal fluid. Despite widespread App brain expression, we hypothesized that specifically targeting choroid plexus expression could alter animal physiology. Through various genetic and viral approaches in the adult mouse, we show that choroid plexus APP levels significantly impact proliferation in both subventricular zone and hippocampus dentate gyrus neurogenic niches. Given the role of Aβ peptides in Alzheimer disease pathogenesis, we also tested whether favoring the production of Aβ in choroid plexus could negatively affect niche functions. After AAV5-mediated long-term expression of human mutated APP specifically in the choroid plexus of adult wild-type mice, we observe reduced niche proliferation, reduced hippocampus APP expression, behavioral defects in reversal learning, and deficits in hippocampal long-term potentiation. Our findings highlight the unique role played by the choroid plexus in regulating brain function and suggest that targeting APP in choroid plexus may provide a means to improve hippocampus function and alleviate disease-related burdens.
O método Cooper, a mídia impressa e a emergência da corrida de rua como prática de saúde no Brasil: uma história de controvérsias e disputas
Authors: Tiburtino Glauber , Gatto Alice
Published: September 2021

O presente artigo se propõe a debater o surgimento da corrida de rua no Brasil como uma prática de saúde que, posteriormente, passou a ser vista com ressalva e desconfiança. Pesquisadores e historiadores do esporte datam a década de 1970 como um marco da expansão da corrida de rua ao redor do mundo. No Brasil, a Copa do Mundo do México teve relevância nessa adesão, uma vez que a utilização do método Cooper pela seleção brasileira de futebol recebeu destaque midiático e a prática rapidamente ganhou aderência nas ruas. O próprio Dr. Kenneth Cooper orientava a corrida como uma das principais fontes de longevidade. Entretanto, essa atividade se mostrou controversa à medida que acidentes e mortes passaram a ocorrer no desempenho de sua prática. Nossa análise centra-se nessa controvérsia e toma por base os olhares e narrativas de meios de comunicação impressos do Rio de Janeiro nas décadas de 1970 e 1980 e da literatura científica em relação a essa disputa de sentidos da corrida de rua como atividade segura e saudável ou de risco.
Expediente
Authors: História da Mídia Associação Brasileira De Pesquisadores de
Published: September 2021

Expediente
The Influence of Respiratory Component on Satisfaction with Physical Therapy after Cardiosurgical Interventions
Authors:   National university of physical training and sport of Ukraine. 1, Fizkultury St., Kyiv 02000, Ukraine, Vitomskyi V. V. ,   Scientific-Practical Medical Center For Pediatric Cardiology And Cardio Surgery, Ministry Of Health Of Ukraine. 28/1, Chornovola St., Kyiv 01135, Ukraine
Published: September 2021

The purpose of the study was to investigate the effect of additional respiratory physical therapy on the level of satisfaction with physical therapy among patients after cardiac surgery. Materials and methods. The study involved 150 patients. The patients were randomly divided into three groups: control (respiratory physical therapy was limited to cough), group of incentive spirometry (in classes with a physical therapist patients performed additional 3 approaches of 10 breaths through the simulator; they received recommendations for hourly performance of a similar number of cycles of exercise), a group of patients who received additional respiratory physical therapy with positive expiratory pressure in the form of exhalation into a bottle of water through a tube (number of repetitions and recommendations are similar to those received by the previous group). All groups underwent the same protocol of mobilization and use of therapeutic physical exercises in the procedure of therapeutic gymnastics. Performing exercises with breathing simulators began on the first postoperative day. Results and discussion. A questionnaire (17 questions) was used to assess the satisfaction with physical therapy. The survey was conducted on the seventh postoperative day. The answers were distributed on a 5-point Likert scale from 1 point to 5 points. The key preoperative indicators and time indicators of surgical interventions of the examined groups did not differ significantly. Analysis of satisfaction with physical therapy revealed a high level in all items of the questionnaire. Statistical differences between the groups were found in only three items of the questionnaire, but they were not related to either the use of equipment or diligence in treatment or the content of physical therapy. The overall score of the questionnaire did not differ in groups according to the Kraskel-Wallis criterion, and Me indicators (25%; 75%) were in the control group – 81 (77; 85) points, in the group of stimulating spirometry – 81 (72; 85) points in the group with positive expiratory pressure – 79 (73; 84) points (χ2 = 4.560; p = 0.102). Conclusion. Additional respiratory physical therapy did not affect the overall satisfaction rate and results of most items of the questionnaire. The differences found in the three items did not indicate any effect of the use of respiratory physical therapy on the level of satisfaction, as higher scores in these items were in the control group. All items in the questionnaire received high scores
Changes in the Functional Indicators of Female Students Based on the Implementation of Individual and Motivational Levels of the Swimming Training System
Authors:   Kherson State University. 27, University St., Kherson 73009, Ukraine, Hluhov I. H. , Pityn M. P. ,   Ivan Boberskiy Lviv State University of Physical Culture. 11, Kostiushko St., Lviv 79000, Ukraine, Drobot K. V. ,   Kherson State University. 27, University St., Kherson 73009, Ukraine, Hluhova H. H. ,   Kherson State University. 27, University St., Kherson 73009, Ukraine
Published: September 2021

The lack of qualitative justification of organizational and methodical support of swimming training process from the standpoint of objective criteria ensuring of health and functional preparedness of student youth determines the relevance of the proposed area of research. The purpose of the study was to establish changes in indicators of functional preparedness of higher educational institutions students based on the implementation of training programs at different individual and motivational levels of the swimming training system. Materials and methods. The study involved girls aged 18-20 years old of Kherson State University. There were four experimental groups representing different individual and motivational levels of swimming (experimental group 1, n=23 girls; experimental group 2, n=26; experimental group 3, n=23; experimental group 4, n=21 respectively) and the control group (n=29) with general lessons. All programs (experimental and control) were designed for 18 lessons during the first semester, the duration of a single lesson was 60 minutes. Changes in body length and weight, heart rate at rest, blood pressure and pulse pressure, Robinson’s, Cardu’s, Kettle’s, Skibinsky’s, Hildenbrant’s, Stange’s and Genche’s indices, Life index and Rosenthal’s test were studied. Results and discussion. Determining the initial level of functional indicators of female students of all experimental groups and control groups gave grounds to the confirmation that the indicator of their values is within the age norm for people who do not do sport. Slightly higher indicators of heart rates at rest for experimental group representatives were obtained. This is due to higher requirements for the cardiovascular and oxygen and transport system of girls in performance of physical activity and specifics of swimming means. Preliminary assumptions, that the absence of maximum physical loads is not able to significantly affect blood pressure, heart rate at rest, a number of indices for both experimental and control training programs, have been confirmed. Conclusion. The qualitative content of physical culture and sports lessons before entering the higher educational institutions forms a certain basis of functional preparedness. It is expressed in indicators at rest and is characterized by optimization of the activity of vital organs and systems of students and can be slightly corrected due to the use of training programs at various individual and motivation levels of the swimming training system for students of higher educational institutions
Simple Interrupted and Continuous Interlocking Suturing Techniques Comparison in Maxillofacial Trauma – A Randomized Controlled Trial
Authors: C H Mahabaleshwara , Francis Mariea , Kumar D Prasanna , Amudhan C R Thamil , Pethkar Radhika , B Shravani
Published: September 2021

Aim: To compare the efficacy of simple interrupted and continuous interlocking suturing techniques using 3-0 vicryl (polyglactin) sutures. Method: The study sample included 20 patients (16 males and four females) with maxillofacial trauma requiring ORIF (Open Reduction and Internal Fixation) of maxilla or mandible fractures. They were randomly allocated to two groups (Group A and Group B). Patients in the age group of 20-50 years, requiring ORIF under local anesthesia or general anesthesia through an intraoral approach and incision measuring 4-6 cm were included in the study. Exclusion criteria included patients requiring extra-oral incisions, comminuted fractures with acute illness, infection, pregnancy, immune compromised conditions and patients not willing to participate in the study. Surgical site was closed in single layer using 3-0 vicryl sutures. Intraoperatively, time taken for suturing, wound dehiscence and wound healing were monitored on third, seventh and 30th day post-operatively. Results: In terms of time taken for suturing, dehiscence of wound and wound healing, continuous interlocking sutures showed superior results than that of simple interrupted sutures. Conclusion: Even though simple interrupted suturing is an easy technique, continuous interlocking suturing technique showed superior results. However, surgeons operating maxillofacial trauma may have their own point of view and selection of technique depends on individual preferences.
Comparative Evaluation of 0.1% Octenidine Mouthwash with 0.2% Chlorhexidine Mouthwash in Prevention of Plaque and Gingivitis – A Clinicomicrobiological Study
Authors: Sadanandan Sowmya , S Suhas , Venugopal Sanjay , Karur Kavitha
Published: September 2021

Background: Our study aimed to assess the efficacy of 0.1% Octenidine mouthwash as an anti-plaque agent and to assess its effect on gingival inflammation and staining of teeth when compared to 0.2% chlorhexidine gluconate by evaluating the impact on plaque and gingival inflammation as well as on microbial load. Materials and Methods: A three week double blind study was conducted on 69 subjects, aged 20-50 years, with moderate to severe gingivitis. The study population was divided into three groups with 23 subjects in each group: Group A - control subjects received only scaling, Group B received 0.2% chlorhexidine gluconate in addition to scaling and Group C received 0.1% Octenidine mouthwash along with scaling. Clinical and microbiological parameters were recorded at baseline, on 14th day and on 21st day. Subjective and objective criteria were assessed on the 14th day and 21st day. Results: There was a statistically significant reduction in all the tested parameters within all the three groups and between the groups from baseline to 21st day. The highest mean reduction in all the parameters was seen in subjects using 0.1% Octenidine. On comparison with the control group, subjects using the mouthwashes (Group B and Group C) had better improvement in clinical and microbiological parameters from baseline to 21st day. On comparison with chlorhexidine, Octenidine mouthwash significantly reduced plaque (p<0.05) and showed better patient acceptability. However, it was comparable to chlorhexidine in other two tested parameters. Conclusion: Owing to Octenidine’s pronounced and comparable antibacterial properties, it can be a promising candidate for the use in antiseptic mouthwashes.
Epidemiology of malaria in Al-Tameem Province, Iraq, 1991-2000
Authors: Kadir M. A. A. , Ismail A. K. M. , Tahir S. S.
Published: September 2021

To determine the rates of malarial infection in different areas of Al-Tameem province, we conducted a cross-sectional study from 1991 to 2000. We found an overall infection rate of 0.76% by Plasmodium vivax. Infection rates were highest in Dibis district [1.12%], followed by infections from outside the province [0.93%] and in Hawija district [0.89%], Kirkuk [0.62%] and Dakok [0.17%]. Rates of infection varied by year with the lowest rate in 1991 [0.02%] and the highest rate in 1996 [1.84%]. All ages were represented, with the highest rate of infection among 21-30-year-olds. Males had a slightly higher rate of infection [0.78%] than females [0.73%]
Selected epidemiological features of human brucellosis in Yazd, Islamic Republic of Iran: 1993-1998
Authors: Salari M. H. , Khalili M. B. , Hassanpour G. R.
Published: September 2021

Brucellosis is a significant health problem in countries where control of zoonoses is inadequate. During 1993-98, we analysed sera and cultures from 792 suspected brucellosis patients who presented with histories of fever, chills, night sweating, weakness, malaise and headache to the referral hospital in Yazd. Cases were investigated by tube agglutination test [TAT] and 2-mercaptoethanol test [2-MET] and a questionnaire was completed for each. TAT titre was > / = 1: 1 60 for 745 patients [94.1%] and 2-MET was positive for 42 [5.3%]. Of 745 confirmed cases, 460 were from 1996-1997. Prevalence was highest in summer [39.5%] and more common males than among females. Prevalence was highest among those aged 10-19 years [27.7%]. Most patients had a history of infected cheese, milk and milk product consumption [98%]
Epidemiology of acute renal failure in hospitalized patients: experience from southern Saudi Arabia
Authors: Al Homrany M.
Published: September 2021

Despite advances in health care, morbidity and mortality associated with acute renal failure [ARF] remain high. This study determined the frequency and etiology of ARF in hospitalized patients in Saudi Arabia over 2 years. Of the 150 cases of ARF, 38.0% were community-acquired and 62.0% hospital-acquired. The main cause was acute tubular necrosis [ATN] in 93 patients, due to sepsis [24.7%], ischaemia [12.7%], rhabdomyolysis [mainly from road traffic accidents] [10.7%], drugs [7.3%] and malaria and snake-bites [4.6%]. Overall, 40% died, 48% made a full recovery and 1 patient [0.7%] became dialysis-dependant. Factors associated with poor prognosis were: age 60+ years, community-acquired ARF, peak blood urea nitrogen > 160 mg/dL, duration of ARF > 1 week, need for dialysis and associated chronic liver disease
The diabetes prevention and control programme of the Islamic Republic of Iran
Authors: Azizi F. , Gouya M. M. , Vazirian P. , Dolatshahi P. , Habibian S.
Published: September 2021

Diabetes mellitus has become a monumental problem and a major health concern throughout the world. We report on the programme developed by the Islamic Republic of Iran for control and management of diabetes, which involves screening for type 2 diabetes in adults at risk and a systematic approach for delivery of health care to people with diabetes
Screening for type 2 diabetes in the Iranian national programme: a preliminary report
Authors: Azizi F. , Guoya M. M. , Vazirian P. , Dolatshati P. , Habbibian S.
Published: September 2021

Diabetes mellitus is a significant threat to public health. It is estimated that more than 1.5 million people with diabetes live in the Islamic Republic of Iran. We report on the preliminary results of the national programme for the prevention & control of type 2 diabetes which began in 1996. The pilot project has so far been instituted in 17 provinces. Of 595 717 people aged 30 years and over, 247 518 were classed as at risk and 3.6% had diabetes, 4.3% of women and 2.6% of men. Diabetes prevalence varied from 1.3% in rural areas to 14.5% in large cities. Early detection and control strategies are aimed at diminishing the heavy burden of diabetes
Hyperhomocysteinaemia, hyperlipidaemia and risk of venous thromboembolism in Shiraz
Authors: Zamani A. , Omrani G. R. , Lankarani K. B.
Published: September 2021

To assess the risk of venous thromboembolism [VTE] associated with hyperhomocysteinaemia [hyper-Hcy] and hyperlipidaemia, we performed a case-control study. Fasting total homocysteine [Hcy], triglyceride and cholesterol levels were assessed in 43 patients with VTE and 43 controls. Mean Hcy level was significantly higher in the test group. Odds ratio [OR] for VTE in patients with hyper-Hcy was 2.7, with the association stronger in women and those under 50. The OR for those with both hypertriglyceridaemia and hypercholesterolaemia was significantly greater in those under 50. Increased risk for venous thrombosis was found among those under 50 having both lipid abnormalities
Teoría del marco relacional: Un enfoque postskinneriano de la cognición y el lenguaje humanos
Authors:   University of Nevada, Reno, NV, United States, Hayes Steven C. , Barnes-Holmes Dermot ,   Ghent University, Ghent, Belgium, Roche Bryan ,   National University of Ireland, Maynooth, Ireland
Published: September 2021

El lenguaje humano y el uso que hacemos de él para comunicarnos o entender el mundo requiere derivar relaciones entre acontecimientos: por ejemplo, si A=B y A=C, entonces B=C. La teoría del marco relacional sostiene que esas interpretaciones son el núcleo de cualquier psicología del lenguaje y la cognición. Desde una edad muy temprana, los seres humanos aprenden relaciones de similitud, diferencia, comparación, tiempo, etc., y modifican lo que hacen en una situación determinada en función de la relación derivada de esta con otras situaciones y lo que saben de ellas. Este volumen va más allá de la teoría y proporciona las herramientas empíricas y conceptuales necesarias para llevar a cabo un análisis experimental de prácticamente todos los temas sustantivos del lenguaje y la cognición humanos, tanto básicos como aplicados. Como sugiere el término “postskinneriano”, este volumen estimula a la psicología conductual al repensar muchas de las formulaciones teóricas específicas de su líder histórico más prominente, especialmente en el ámbito del lenguaje y la cognición proponiendo nuevas direcciones. La necesidad de un análisis pragmático del lenguaje y la cognición es conmensurable a las extensiones y aplicaciones de tal formulación. Este libro será de interés no sólo para los teóricos de la conducta, sino también para los psicólogos cognitivos, terapeutas, educadores y cualquier persona que se interese por la conducta humana.
Evaluation of Aquifer Porosity And Hydraulic Conductivity From Empirical Equations Using Geoelectrical Sounding Measurements In Piramagroon Area NE-Iraq
Authors: Amin Abdulla Karim
Published: September 2021

Application of Vertical Electrical Sounding (VES) with Schlumberger array as a low-cost technique and veritable method in groundwater exploration is more suitable for hydrogeological survey of sedimentary basins. This method is regularly used to solve a wide variety of ground water problems and hydraulic parameters. The main objective of this research therefore, is to evaluate aquifer porosity and hydraulic conductivity using the empirical equations of porosity and hydraulic conductivity with resistivity conducted in the continuation of the adjacent Sharazoor basin. For this purpose, four profiles were taken in studied area (Piramagroon district), and each profile includes five VES points of measurements. Then each VES was interpreted manually as well as by IPI2 win program for determining aquifer depth ranging from (40 m.) to (80 m.) in piramagroon district) and resistivity values range between (37.0 Ω.m) to (102 Ω.m), which are substituted in the empirical porosity-resistivity and hydraulic conductivity-resistivity equations for evaluating aquifer porosity and hydraulic conductivity of the studied area. The estimated aquifer porosity values range along the studied area  range between (21%) to (39 %), and for hydraulic conductivity values range from (1 m/day) to (4 m/day), which shows the increasing of the both aquifer porosity from the top of uplifted subsurface layers underlying the piramagroon district toward both limbs according to increasing of rock fragments (gravel, pebble) and (sand sediments) and decreasing of clay content overlying upper part of Middle Tanjero Formation.
Leyendo una Currícula de Ciencias Naturales en un Abordaje Freiriano: el Caso de los Diseños Curriculares de la Provincia de Buenos Aires, Argentina
Authors: Defago Alejandra , Ithuralde Raúl Esteban
Published: September 2021

La provincia de Buenos Aires sancionó sus Diseños Curriculares para la Educación Secundaria Orientada entre los años 2010 y 2012. En estos se sostiene que para la Educación en Ciencias Naturales que ésta tiene como objetivo la formación para la participación ciudadana y que las Ciencias son actividades sociales y humanas situadas histórica y culturalmente. Estas definiciones dejan el camino abierto para que, en las aulas, se puedan desarrollar prácticas que se acerquen progresivamente a la Educación Popular en esta área. En este trabajo presentamos los resultados de observaciones de clases de Ciencias Naturales que reconocemos que trabajan en perspectiva freiriana, identificando elementos clave necesarios para esta integración. Hallamos que las estrategias privilegiadas para interpretar los Diseños Curriculares en un abordaje emancipatorio son: el llevar adelante una educación situada, recuperando problemáticas de los grupos sociales que asisten a la escuela y pensada desde la justicia curricular, y el construir vínculos con la comunidad.
Inventory of the Kirillo-Belozersky Monastery (1615): An Experience of Using Spectrosonal Visualization to Reconstruct the History of the Text
Authors:   St. Petersburg Institute of History of the Russian Academy of Sciences, St. Petersburg, Russian Federation, Lyakhovitskii Evgeny A.
Published: September 2021

The article describes the results of a codicological study of the Inventory of the Kirillo-Belozersky (St. Cyrill of Beloozero) Monastery (1615). The main codicological problem for the researchers posed by this monument is its numerous and asynchronical edits. It is possible to identify edit layers by studying the ink by means of spectrosonal imaging in near-IR wavelength region of the spectrum. This method is based on the property of inks (except those with a carbon base) to acquire transparency beyond the visible region of the spectrum (after 700 nm). As additional information, visually observed (in natural indirect daylight) color differences between inks have been used, as well as color estimation using a digital portable microscope Dinolite with Dinoscope software. As a result of the study, the main stages of work on the Inventory have been established. A significant part of the marginalia are in the same ink and handwriting as the main text: brown, with moderate transparency in near-IR wavelength region. Thus, the text was probably supplemented in the course of creation. This edit was accompanied by the text on the insert sheets made in ink that is slightly translucent in the IR region of the spectrum and has a dark brown color. The same ink was used in the main text of the manuscript. When the main text was rewritten in 1616-1617, it was compiled in a codex and significantly revised for the first time. The marker of this revision stage is light brown and yellowish-brown ink with high degree of transparency in IR wavelength region of the spectrum. In addition to the editing, the notebooks are numbered in the same light brown ink. The edit of this layer mainly included clarifications to the items description. The next significant revision of the inventory text, marked with brown ink that has low transparent in the IR wavelength region of the spectrum, refers to the period after July 22, 1621. Most of these edits, as well as the earlier ones, were devoted to clarifying descriptions, to clarifying location of objects, and to describing the monastery’s acquisitions and losses. Apparently, the later stage of editing is associated with the use of gray-brown ink, similar in spectral behavior to the ink of the main text. The record of the contribution of Prince Khvorostinin made in 1622–23 was written in this ink.
V. N. Weber’s Diary on the Work of the Russian-Swedish Grade Measurement Expedition to the Svalbard Archipelago in 1901
Authors:   Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Syktyvkar, Russian Federation, Filippova Tatyana P.
Published: September 2021

The article concentrates on the study of historical experience of the Russian science in the development of the Arctic and the northern territories. The object of its analysis is the travel diary of the geologist, Doctor of Geological and Mineralogical Sciences (1937), employee of the Geological Committee of Russia,Valerian Nikolaevich Weber (1871–1940), a participant of the Russian-Swedish expedition on grade measurement on the Svalbard archipelago in 1901, stored in fond no. 58 “The Geological Committee of the Mining Department” of the Russian State Historical Archive. The Russian-Swedish grade measurement expedition to the Svalbard archipelago was carried out in 1899-1901 and became one of the major international scientific projects for studying the Arctic space at the turn of the 20th century. The results of this expedition went down in the history of the Arctic studies, and its results laid the foundations for the modern study of polar territories. The travel diary of V.N. Weber covers the period from May 27, 1901 to August 18, 1901 and describes the activities of the Russian researchers on board of the icebreaker Yermak in 1901. This documentary source is a unique historic monument, not only revealing the history of the expedition research, but also showing all its events in assessment and interpretation of a participant. In Soviet historiography such sources were considered supplementary, but modern trends in of historical scholarship allow us to analyze such documents as independent subjects of study. Travel diaries are kept in order to preserve the memory and for practical purposes of the expedition. Such sources usually have rich information potential, representing various aspects of the expedition’s activities; regular travel notes reflect, as a rule, a consistent course of events, providing valuable retrospective information for research. The diary of V.N. Weber details the route of the research party, the living conditions and daily life of the expedition participants, their scientific activities and the research results. Analysis of the diary demonstrates what efforts won great results for the Russian scientific community in the development of the Arctic territory in the early 20th century. This document, being a valuable source for scientific study and comprehension of the Arctic, helps the modern generation to understand this unique historical experience.
“Killed in An Explosion in the House of the Supreme Ruler”: Concerning the Analysis of Death Records of the Officers of the Admiral A. V. Kolchak’s Convoy, August 27, 1919
Authors:   Omsk State Technical University, Omsk, Russian Federation, Petin Dmitrii I. , Stelmak Maksim M. ,   Historical Archive of Omsk Region, Omsk, Russian Federation
Published: September 2021

The study is devoted to the analysis of a group of unknown sources from the Historical Archive of the Omsk Region (fond of the Omsk Spiritual Consistory) that are being introduced into scientific use for the first time. These documents are associated with a tragic incident that resulted in the death of seven lower ranks, who provided security for Admiral A. V. Kolchak in Omsk. The contemporaries’ memoirs have served as an auxiliary source in the study. The relevance of this work is justified by contradictions in modern historiographic discussion regarding the cause of the explosion in the vicinity of the private residence of the Supreme Ruler in Omsk on August 25, 1919, as well as by great interest of the national scientific community in his person. Anthropological approach, principle of consistency, historical-systemic and comparative-historical method have served as methodological basis for the study. This theoretical totality suggests two points. First, consideration of the identified vital records as a natural consequence of the work of the Institute of the Russian Orthodox Church; second, critical comparative analysis of the new data and previous developments in historiography. The identified records have made it possible to establish the exact number of servicemen who died as a result of the tragedy, as well as their names, belonging to the service category of the lower ranks of the White Army, date of death, place and date of the funeral service and burial. The authors point out that the analyzed sources are also of key importance for studying the last days of the Omsk poet Yuri (Peter Ivanovich) Sopov, one of the victims of the explosion. In the conclusion, the thesis is emphasized of the need for basic and contextual use of vital records as a valuable documentary source on the past for conducting research on various aspects of the history of the Civil War. This publication may be of interest to specialists in source studies, researchers of the Civil War in the East of Russia, state security agencies of the anti-Bolshevik authorities, biography of Admiral A. V. Kolchak, local Omsk history.
Influence of Russian Modernization on the Management System in the Komi Region in the 18th Century
Authors:   Komi Republican Academy of State Service and Administration, Syktyvkar, Russian Federation, Gagieva Anna K.
Published: September 2021

The article addresses major issues of influence of the modernization on the management system in the Komi region in the 18th century The relevance of the study is due to the fact that today in historical science there are a number of interesting concepts explaining interaction and mutual influence of all levels of government, both central and local. This refers to the theory of modernization, which allows us to identify local variants in regional management and to emphasize their alternativeness against the industry morphology. In this case, the state actively included the annexed territories into socio-economic relations and active administrative and state construction. The Komi region, as well as its neighboring regions, experienced a transfer of management technologies from the center and its neighboring regions, which resulted in formation of several local forms of management. The first one was represented by heads of administrative structures, officials of the uezd administration. Their main functions were administrative and economic, judicial and supervisory. Their sphere of responsibility varied and changed to follow the trend of strict regulation of their activities; all adjustments were made exclusively by the governor. Alongside with this first group, there was peasant volost administration, which had been operating on the territory of the Komi region for a long time. Its main functions lay in solving fiscal, land, economic, residential and other issues. Both were administrating authorities, constantly changing in the studied period. The second local administrative structure was represented by managers and employees of industrial enterprises: Seregovo saltworks and Kazhym metal works (mines in Nyuvchim, Nyuchpas and Kazhym). The key functions of their employees were administrative and economic, supervisory, and supply ones. Their sphere of responsibility varied and was adjusted by the plant owners. Yet another local model, characteristic for the 18th century, was represented by officers and heads of garrison offices in military camps. Their main activity was solution of various defense and supply tasks. When analyzing the influence of modernization on these elements of management in the Komi region in the 18th century, its progressive convergence should be noted. There was a complex administrative and managerial framework. Its formation was influenced by impulses coming to the periphery (in our case to the Komi region) from the central government.
State of Human Resources in the Regional Food Industry in the First Post-War Years: 1946–48
Authors:   South-West State University, Kursk, Russian Federation, Vorontsov Roman S. , Korovin Vladimir V. ,   South-West State University, Kursk, Russian Federation
Published: September 2021

The article is based on the analysis of a wide range of documentary sources reflecting qualitative characteristics of production personnel of regional food industry enterprises. The authors consider the problems of industry staffing in the first years following the end of the Great Patriotic War. The historiography of the topic is represented by publications on various aspects of national industry development, which take into account modern achievements of historical science and development of source base. However, assessment of qualification and social maturity of human resources, material conditions of work, and influence of all these factors on the efficiency of food industry have not yet been subject of special research. The territorial framework of the study is limited the Kursk region in its borders prior to 1954. On this territory, which was a part of the Central Black Earth economic region of the RSFSR, the food industry was a traditional and developing branch of production, as it had its own potent raw material base. The solution of staffing problems in the post-war years was significantly affected by the region’s front-line situation, which has influenced the nature of the tasks to be solved. The main sources are executive directives of government bodies and record keeping materials of enterprises, which characterize the state of the industry human resources. The documentary materials used in preparation of this article have been identified by the authors in the fonds of the Russian State Archive of Economics and in the State Archive of the Kursk Region. They reveal the multi-factorial process of providing the food industry, the main branch of regional economy, with competent employees. The authors have analyzed the content of the documents and presented, on the basis of archival sources, a general overview of the human resources in the industry in the post-war years of reconstruction and modernization. The most informative, from the point of view of the designated topic, are the regional archival fonds. The documentary sources used in the preparation of the article address the situation with personnel in the regional food industry in 1946–48 years quite objectively. Their introduction into scientific use contributes to authoritative depiction of personnel policy implemented locally in the days of post-war economic recovery.
Review of the Personal Fund of Grand Duke Sergey Alexandrovich in the State Archive of the Russian Federation
Authors:   Perm State National Research University, Perm, Russian Federation, Sofjin Dmitriy M. , Sofjina Marina V. ,   Perm State Institute of Culture, Perm, Russian Federation
Published: September 2021

This article presents an overview of the personal fund of Grand Duke Sergey Alexandrovich, a member of the Russian Imperial House, the younger brother of Emperor Alexander III, an outstanding state, military and public figure who held the posts of Moscow Governor-General, Commander of the Moscow Military District, Chairman of the Imperial Orthodox Palestine Society. The fund, formed and described in the Soviet era, contains 160 cases, including youth and adult personal diaries of the fund-builder, epistolary, educational and official documents, photographs and other illustrative materials, and other documents. Various groups of storage units of the fund are analyzed, the features of each group and its information potential, the quantitative and qualitative characteristics of the materials, the source analysis of the most important documents is given. Special attention is paid to the diaries of Grand Duke Sergey Alexandrovich and the letters of his correspondents, among which the most significant historical sources should be recognized as the letters of his nephew, Emperor Nicholas II, his cousin and friend, Grand Duke Konstantin Konstantinovich, Ober-Procurator of the Most Holy Synod Konstantin Pobedonostsev, a former teacher of the fund-builder. These documents, among other things, cover important issues of state policy, show the behind-the-scenes side of making certain decisions in the leadership of the country. The fund also deposited letters and telegrams from other outstanding Russian figures – Alexander III, Commander-in-Chief of the Guard Troops and the Petersburg Military District Grand Duke Vladimir Alexandrovich, Minister of the Interior Vyacheslav von Plehve, Minister of War Aleksey Kuropatkin, Minister of Justice Nikolay Muravyov, Metropolitan Sergius of Moscow. Among the official documents, it is particularly necessary to highlight the reports of the Moscow commandant to Grand Duke Sergey Alexandrovich as the Moscow Governor-General, given at the time of celebrations during the coronation of Nicholas II. These materials shed additional light on the organizational aspects of the last coronation in the history of the Russian Empire. The fund has a fairly extensive collection of illustrative material, primarily photographs, including photographs taken personally by Grand Duke Sergey Alexandrovich. A significant array of storage units of the fund has already been put into scientific circulation, and some materials have been published. At the same time, many documents still require research.
The Siberian Church Council: Experience of Modern Archeography
Authors:   The Siberian Church Council: Experience of Modern Archeography, Sushko Aleksey V.
Published: September 2021

The article is a review of a documents collection “The Siberian Council Meeting of 1918: Materials” repared by the well known Omsk church historian Dmitry Vladimirovich Olikhov. It was published in Moscow in 2020. It contains an informative introductory article on the Siberian Council and publishes its documents known at present date, as well as materials from the periodicals and memoirs. The article emphasizes the relevance of the book and its scientific significance. Institutional and historical-anthropological approaches provide scientific basis to the documents collection and, accordingly, to this article devoted to its analysis. The principles of consistency and determinism have made it possible to characterize the publication, considered as a phenomenon of science with its particular structure and at the same time as a part of the historical scholarship. Due to specifics of the topic, the main scientific method used in this publication is problematic. The article contains critical remarks and considerations on the introductory article prefacing the analyzed documents collection. It offers its opinions on main initiators of the Tomsk Council and its results. The article disputes the author-compiler’s point of view that the Siberian Council managed to avoid political extremes. Drawing on the analysis of documentary materials from the said collection, the author of the article claims that the Tomsk Council Meeting created conditions for consolidation of right-wing politicians and religious leaders on anti-Bolshevik platform. Despite his expressed criticism, the author of this article is of the opinion that publication of generally available materials on the Siberian Council Meeting and similar publications on the All-Ukrainian Church Council and the South-Eastern Church Council create opportunities for comparative historical analyses of these church forums. In conclusion the article expresses hope that the established source base should allow us to expect an appearance of new articles and monographs on the development of the conciliar principle in the Russian Orthodox Church during the Civil War in Russia.
Dönüştürücü Liderliğin Örgütsel Çeviklik Üzerine Etkisi
Authors: ERDEM BALCI Beyza , ERBAY Elif Özge
Published: September 2021

Bu araştırmanın temel amacı dönüştürücü liderlik ile örgütsel çeviklik arasındaki ilişkiyi perakende sektörü çalışanları bağlamında incelemektir. Literatüre bakıldığında liderlik kavramına dair pek çok çalışmaya rastlanmakta, örgütsel çeviklik faaliyetlerine ilişkin çalışmaların oldukça sınırlı olduğu görülmektedir. Bu doğrultuda sürekli değişen iş dünyasında örgütlerin ihtiyacı olan çevik yaklaşımın gerçekleşebilmesi için dönüştürücü liderlik özellikleri ile ilişkili olabileceği düşünülmüş ve buradan hareketle bu çalışmanın literatüre katkı sağlaması amaçlanmıştır. Vurgulanmak istenen nokta, örgüt içindeki yöneticilerin liderlik özelliklerine dönüştürücü liderlik özelliklerinin de dahil edilmesiyle çevik örgütlere dönüşümünde başarılı bir şekilde gerçekleştirilebileceğidir. Bu bağlamda, bu çalışma ile çevik bir yapıya geçmeyi planlayan örgütlere de yapılanma süreçlerine dair önerilerle katkı sağlanabileceği düşünülmektedir.
FİRMALARIN SOSYAL MEDYA KULLANIMLARININ AĞ, SEKTÖR VE FİNANSAL PERFORMANS AÇISINDAN ARAŞTIRILMASI: BIST UYGULAMASI
Authors: ÖZEVİN Onur
Published: September 2021

Çalışmanın amacı Borsa İstanbul’da işlem gören firmaların sosyal medya kullanım tercihlerinin sosyal medya ağı, sektör ve finansal performans açısından araştırılmasıdır. Araştırma BIST 100 endeksinde işlem gören şirketlerin 2019 yılı sonu verileri ile sınırladır. Çalışma sonucunda şirketlerin en çok tercih ettikleri sosyal medya ağı “Linkedin” olarak tespit edilmiştir. Araştırmaya dâhil 11 sektör içinde sosyal medyayı en aktif kullanan sektörler “ulaştırma ve haberleşme” sektörü ile “toptan ve perakende ticaret” sektörleridir. Araştırmaya konu olan şirketler içinde her bir şirket ortalama 3,5 farklı sosyal medya ağı hesabına sahiptir. Bu sayı sosyal medyayı aktif kullanan grupta 4,5 iken aktif olmayan grupta ise 2,30’dur. Sonuçlar, sosyal medyayı aktif kullanan firmaların “Fiyat/Kazanç oranı”, “Firma Değeri/Net Satışlar oranı”, “Piyasa Değeri” ve “Özsermaye Karlılığı” oranlarının, aktif kullanmayan firmalara göre anlamlı şekilde farklılaştığını göstermektedir. Araştırılan diğer finansal oranlarda anlamlı bir farklılık bulunamamıştır.
TÜRKİYE CUMHURİYET MERKEZ BANKASI REZERVLERİNİN HEGY TESTİ İLE MEVSİMSELLİK ANALİZİ
Authors: ŞEKER Kudbeddin
Published: September 2021

Bu çalışmada Türkiye Cumhuriyet Merkez Bankası rezervlerinde mevsimsel etkinin tespiti amaçlanmıştır. Böylece mevsimsel birim köklerin tahmini ile birim kök giderme yöntemi, verilerin buna göre modellenmesi ve tahmini daha tutarlı olacaktır. Bunun için 1983:2 - 2020:4 yılları arası Türkiye Cumhuriyet Merkez Bankası rezerv miktarına ait üçer aylık veriler kullanılmıştır. Bu verilerden oluşan zaman serisinin mevsimsel etkiye sahip olup olmadığı HEGY (1990) tarafından kullanılan mevsimsel birim kök testi ile araştırılmıştır. TCMB rezerv serisi için HEGY testi ile yapılan mevsimsel birim kök testi analizi sonucunda, sıfır frekansta tüm modellerde birim kök içerdiği görülmüştür. Yarıyıllık frekansta sabit terim ve mevsimsel kukla değişkenleri ile sabit terim + trend ve mevsimsel kukla değişkenlerin bulunduğu modellerde mevsimsel birim kök mevcuttur. Ayrıca ¼ ve ¾ çeyrek yıllık frekanslarda belirtilen tüm modeller için mevsimsel birim kökün olmadığı tespit edilmiştir.
Covid-19 Türk Sigorta Sektörünü Nasıl Etkiledi?
Authors: MERAL Hasan
Published: September 2021

2020 yılı başından itibaren tüm dünyayı tesiri altına alan Covid-19 pandemisi küresel ekonomiyi derinden etkilemiş, Türkiye ekonomisi de bu süreçte önemli kayıplar yaşamıştır. Türk sigorta sektörü 2020 yılında diğer birçok sektörün aksine güçlü bir büyüme performansı göstermiş ve teknik sonuçlarını iyileştirmiştir. Bununla birlikte, teknik sonuçlardaki iyileşmenin aksine Türk sigorta sektörünün uzun yıllardır süregelen yapısal problemleri pandemi döneminde de varlığını sürdürmüştür.

Çalışmada, Türk sigorta sektörünün 2016-2020 yılları arasındaki performansı hayat dışı ve hayat branşları ayrımında, entropi ağırlıklandırmalı TOPSIS yöntemi ile analiz edilmiş, pandemi etkisi altındaki 2020 yılı performansı diğer yıllar ile karşılaştırılmıştır. Uygulama sonuçlarına göre, hayat dışı branş en yüksek performansı 2020 yılında, hayat branşı ise 2018 yılında göstermiştir. Bu bağlamda, Covid-19 pandemisinin Türk sigorta sektöründe hayat dışı branşın performansı üzerinde herhangi bir olumsuz etkisinin olmadığı, hayat branşının performansını ise sınırlı da olsa negatif şekilde etkilediği sonucuna ulaşılmıştır.
Physical, Mechanical and Thermal Properties of Red Pine Wood-Gypsum Particleboard
Authors: KAYA Ali İhsan , YALÇIN Ömer Ümit , TÜRKER Yasemin
Published: September 2021

Physical, mechanical and some thermal properties of gypsum-wood mixture particleboards were analyzed for specimens which were prepared in different proportions previously conditioned at 23 ˚C and 65% relative humidity. Water absorbtion (WA) and thickness swelling (TS) properties were measured after soaked in water for 24 hours. Furthermore, the increment of wood particle was increased the water absobtion values around 28.5 % and 2.1% thickness swelling values, respectively. However, the reduction of gypsum ratio was negatively effected the mechanical resistance of the boards. The highest MOR, MOE and internal bond (IB) values were observed in the C1 code board with 4.73 MPa, 27.04 MPa and 0.97 N/mm2 respectively. The thermal conductivty of wood-gypsum boards were ranged from 0.7404-0.5021 W/mK. The highest density was found in C1 type board as 1.333 kg/m³ and also the highest thermal coductivity was observed at the same sample. Besides, the highest surface temprature which was passed to opposite side of flame source, was found in C5 as 141.7 oC after 300 seconds. However, the lowest value was observed in C1 type board as 93.3 ˚C after 300 seconds.
Eff ect of nebivolol and carvedilol on the functional state of patients with chronic heart failure and preserved left ventricular ejection fraction
Authors: Tregubov V. G. , Khilkevich P. V. , Shubitidze I. Z. , Pokrovskii V. M. , Yukhnova N. V.
Published: September 2021

Objective. Compare the eff ect of combination therapy with nebivolol or carvedilol on the functional state of patients with chronic heart failure (CHF) and preserved ejection fraction (pEF) of the left ventricle (LV). Material and methods. The study involved 80 patients with diastolic CHF, who were randomized into two groups. In group I was appointed of nebivolol (7.7 ± 2.4 mg/day, n = 40), in group II — carvedilol (30.5 ± 8.7 mg/day, n = 40). As part of the combination therapy, quinapril was prescribed (13.7 ± 2.7 mg/day, n = 40 and 13.5 ± 2.6 mg/day, n = 40), and if indicated — atorvastatin (15.3 ± 4.6 mg/day, n = 17 and 16.2 ± 5.2 mg/day, n = 17) and acetylsalicylic acid in the intestinal soluble shell (96.4 ± 13.4 mg/day, n = 14 and 93.8 ± 13.3 mg/day, n = 13), respectively. Initially and after 6 months of therapy were carried out: quantitative assessment of regulatory-adaptive status (RAS) (by means of a sample of cardiac-respiratory synchronism), echocardioscopy, treadmill test, test with a six-minute walk, subjective assessment of quality of life, determination of the level of the N-terminal fragment of the brain natriuretic peptide in blood plasma, daily monitoring of blood pressure. Results. Both schemes of combined therapy comparably improved the structural and functional state of the heart, controlled arterial hypertension. In comparison with carvedilol, nebivolol diff ered positive eff ect on the RAS, more increased tolerance to physical activity and improved quality of life. Conclusion. In patients with CHF pEF LV in combination therapy, the use of nebivolol, in comparison with carvedilol, may be preferable due to the more pronounced positive eff ect on the functional state.