bluuebunny/crossref_metadata_2025 huggingface dataset:
Experiências vivenciadas da residência pedagógica em tempos de pandemia: contribuição na formação docente
Authors: Velôso Jaqueline da Rocha , Laureano Lenilda de Fátima de Jesus , Stropa Jusinei Meireles , Cunha Geremias Dourado da
Published: August 2022

O presente trabalho por objetivo relatar as experiências vivenciadas durante seis meses da participação do residente licenciando em Química no Programa de Residência Pedagógica (PIRP), entre o período de outubro do ano de 2020 a março de 2021, cujo propósito é o preparo do acadêmico para o mercado de trabalhado sendo oportuno na relação teoria e prática. O projeto do Residência nesse módulo foi executado remotamente, visando a segurança dos acadêmicos e alunos da instituição campo em período de pandemia do Covid-19 (Sars-CoV-2). Deste modo para o cumprimento das atividades dos residentes os mesmos tiveram que se adequar ao ensino a distância onde contaram com o uso de diversas ferramentas tecnológicas, assim como o PowerPoint®, Canva® e OBS studio®, para o preparo de materiais, confecções de telas e áudios em que foram gravados. Durante a produção das videoaulas utilizou-se diversos aplicativos para a edição, sendo eles KineMaster®, YouCut-Video Editor® e Video Transcoder®. Após as edições das videoaulas utilizou-se a ferramenta do Youtube® para as postagens das mesmas, facilitando a chegada destes materiais até os alunos da escola-campo. Os links das videoaulas produzidas com conteúdo e exercícios eram disponibilizados nos grupos do WhatsApp em que estavam presentes, os alunos da escola- campo, o preceptor e os residentes inseridos nessa escola. Para as observações e preparação de equipe utilizou-se a plataforma do Google Meet®. Considera-se que a experiência do residente nesse período de ensino remoto, teve bastante relevância preparando-o em sua caminhada “docente” aperfeiçoando para diversas situações de ensino.
CLIL for the teaching of History and English in Secondary Education: How to complete the existing materials
Authors: Vela Rodrigo Alberto Ángel
Published: July 2022

The importance of CLIL can be understood by the new demands in education and the changing social forces that affect the use of languages in applied contexts today. Therefore, the use of appropriate materials is basic. The aim of this paper is two-fold. Firstly, to establish the key elements of CLIL, reviewing the theoretical frameworks informing this methodology to identify its basic characteristics. Secondly, to examine to what extent they are applied in the teaching of History through a real example of a textbook for 2nd year of Secondary Education. To fulfil both aims, a list of nine criteria has been developed to be used as a relevant tool for teachers when choosing potentially effective materials. This tool will be inspired in the guidelines of two CLIL models in terms of SLA and content support. Finally, possible niches for improvement will be detected, always in order to increase students’ motivation.
On some aspects of the use of the trust management in the Russian Federation as a tool to prevent conflicts of interest
Authors: Gorokhova Svetlana Sergeevna
Published: July 2022

The subject of the study is the norms of Russian administrative law regulating the obligation for state and municipal employees (and some other categories of persons) to transfer securities, participation shares, shares in the authorized (stock) capitals of organizations to trust management, within the framework of the institute for the prevention and control of conflicts of private and public interests in the process of these persons performing their direct responsibilities. In the course of this study, the author intentionally does not address the issues of civil law regulation of the trust management agreement, focusing on the organizational and administrative side of the studied relations, nevertheless, stating that the application of civil law norms to administrative relations is also not free from a number of problems. The main conclusions of the study are the following points. The Federal Law "On Combating Corruption" prescribes certain categories of persons to transfer securities belonging to them, etc., to trust management if possession of them leads or may lead to a conflict of interests. This norm is variably duplicated in a number of laws and by-laws. At the same time, a number of laws establish the obligation for designated persons to transfer their valuables to trust management, due to the occurrence of a conflict of interests, others assume unconditional transfer. Article 12.3 of the Law "On Combating Corruption" contains a reference to civil legislation regulating the trust management of property as a civil contract. This determines additional issues related to the application of civil legislation in the context of administrative and legal relations. Based on judicial practice, the transfer of property to trust management does not limit the right of the founder of the management to dispose of the management object. In this regard, there are reasonable doubts about the effectiveness of the transfer of conflict-prone property by employees and other persons, in simple trust management, as a way to prevent (prevent) conflicts of interest.
Questioning on Several Forms of Fascism
Authors: Sumah Stefan , Sumah Anze
Published: July 2022

The concept of fascism has been defined quite precisely by researchers in the field of political science and sociology, who also defined its main features or characteristics. However, with the word fascism (and its derivatives, e.g. fascists, fascist…) members of the left often label their opponents, thus, this is word is often misused. In essence, fascism is a word that has become synonymous with the word totalitarianism. With the analysis that was based on similar characteristics we concluded that totalitarianisms of both poles (if the classical left–right political spectrum is applied) exhibit more common features than, for instance, totalitarianisms and classical dictatorships, which are also often called fascist or semi-fascist regimes. Thus, German Nazism (often also presented as one of the forms of fascism) and Russian Bolshevism (as one of the extremes forms of socialism) or Titoism in Yugoslavia have more in common than e.g. German Nazism and Pinochet’s dictatorship in Chile or the dictatorship of colonels in Greece (both also frequently referred to as fascistic regimes or semi-fascist regimes). Using the word fascism is often not so much about denoting the actual content as it is more for political propaganda and slandering the opponent. If it was based on actual characteristics, fascism (fascist, fascists…) could become an adjective to denote all totalitarianisms (left fascism, right-wing fascism, Islamic fascism…).
Post-Kantian Perfectionism. A Study in the Political Thought of German Idealism, from Leibniz to Marx
Authors: Moggach Douglas
Published: July 2022

The political salience of policy issue arenas related to the movement of people, including immigration, citizenship, and asylum, has increased in recent decades and is likely to continue to escalate for the foreseeable future, because of both real dynamics of migration flows and because of political dynamics including reactions to the Covid-19 pandemic. Existing governance regimes at the global, regional, and national levels somewhat order the migration issue arena and do much humanitarian good, but they also generate new problems and injustices. The perception of disorder in migration and citizenship are likely to continue to present challenges for liberal democracy and for international cooperation. This article outlines the contours of challenges of governing the movement of people since the end of the Cold War.
Shaping Pluralistic Cohesive Societies
Authors: Mohamed Ghouse Mike
Published: July 2022

This paper aims to prepare an individual to function effectively in a constantly changing multi-faith, multi-cultural, multi-racial, multi-ethnic, and multi-everything society with minimum conflicts. Pluralism is a new subject with a focus on its effect on different aspects of life in building cohesive societies where no one has to live in apprehension or fear of the other. Pluralism means respecting the otherness of others in religion, culture, politics, and the workplace. You may see people of different faiths, races, cultures, and ethnicities interacting, working, studying, intermingling, playing, and marrying each other. A decade from now, you may not see the monopoly of a race or cultural groups in the workplace, place of worship, school, bus, train, theater, library, or other public gatherings. These interactions between people not familiar with each other’s culture lend themselves to misunderstandings and are bound to create conflicts. As responsible members of society, we must prepare ourselves to prevent possible challenges and lay a foundation for the effective functioning of institutions where every human feels secure about his faith, race, ethnicity, culture, language, political or sexual orientation, or any other uniqueness. Exclusive communities will become a thing of the past. If you live amidst others, you should also respect the otherness of others, as you expect them to do the same for you.
Income Earner Status and Couple Type and Its Impact on Marital Satisfaction
Authors: Ratnasari Yudiana , Fatheya Fath
Published: July 2022

The rise of opportunities for females to work outside household settings in Indonesia has changed the division of traditional roles and responsibilities among married couples and thus may affect the quality of marital relationships. This study aims to observe how income earner status (single or dual earner) within families and couple type play roles in marital satisfaction. The participants comprised 224 spousal couples who are analyzed individually and together to categorize couple types measured using the Relational Dimension Instrument and Couple Satisfaction Index. Results indicate that for income earner status, no significant predominant effect on marital satisfaction was observed. The average marital satisfaction scores between couples with single- and dual-income statuses were insignificantly different, suggesting that dual- or single-income status does not have a direct effect on marital satisfaction. Based on couple type, traditional and separated types showed the highest marital satisfaction mean scores and lowest marital satisfaction scores among other types, respectively. These results reveal that interdependence and conflict resolution communication are important aspects in determining marital satisfaction levels among the Indonesian couples who participated in this study.
On the Reproductive Biology of Alkanna tinctoria (Boraginaceae)
Authors: Yankova Elina , Grancharova Petka , Nikolova Rozalia
Published: July 2022

In the present study main parameters of reproductive biology as features of embryological structures and processes as well as the pollen and seed viability of Alkanna tinctoria, an endangered useful species of Bulgarian flora were established. In its studied Bulgarian populations pollen viability above 90% and seed viability – between 32% and 64% were determined. The anthers are tetrasporangiate and their wall develops according to Dicotyledonous-type, consisting of an epidermis, fibrous endothecium, an ephemeral middle layer and secretory tapetum. The microsporogenesis is simultaneous and in the anthers tetrahedral and isobilateral microspore tetrads are formed. The mature pollen is threecelled at shedding stage. The ovule is anatropous, teniunucellate, unitegmic. Embryo sac (ES) develops according to the Polygonum (monosporic)-type. The embryo development follows the Asterad-type. The endosperm in the mature seeds has been completely consumed. As a result of the present study A. tinctoria is characterized as a sexually reproducing species.
Natural killer (NK) cell-derived extracellular-vesicle shuttled microRNAs control T cell responses
Authors: Dosil Sara G , Lopez-Cobo Sheila , Rodriguez-Galan Ana , Fernandez-Delgado Irene , Ramirez-Huesca Marta , Milan-Rois Paula , Castellanos Milagros , Somoza Alvaro , Gómez Manuel José , Reyburn Hugh T , Vales-Gomez Mar , Sánchez Madrid Francisco , Fernandez-Messina Lola
Published: July 2022

Natural killer (NK) cells recognize and kill target cells undergoing different types of stress. NK cells are also capable of modulating immune responses. In particular, they regulate T cell functions. Small RNA next-generation sequencing of resting and activated human NK cells and their secreted extracellular vesicles (EVs) led to the identification of a specific repertoire of NK-EV-associated microRNAs and their post-transcriptional modifications signature. Several microRNAs of NK-EVs, namely miR-10b-5p, miR-92a-3p, and miR-155-5p, specifically target molecules involved in Th1 responses. NK-EVs promote the downregulation of GATA3 mRNA in CD4+ T cells and subsequent TBX21 de-repression that leads to Th1 polarization and IFN-γ and IL-2 production. NK-EVs also have an effect on monocyte and moDCs (monocyte-derived dendritic cells) function, driving their activation and increased presentation and costimulatory functions. Nanoparticle-delivered NK-EV microRNAs partially recapitulate NK-EV effects in mice. Our results provide new insights on the immunomodulatory roles of NK-EVs that may help to improve their use as immunotherapeutic tools.
Prolonged β-adrenergic stimulation disperses ryanodine receptor clusters in cardiomyocytes and has implications for heart failure
Authors: Shen Xin , van den Brink Jonas , Bergan-Dahl Anna , Kolstad Terje R , Norden Einar S , Hou Yufeng , Laasmaa Martin , Aguilar-Sanchez Yuriana , Quick Ann P , Espe Emil KS , Sjaastad Ivar , Wehrens Xander HT , Edwards Andrew G , Soeller Christian , Louch William E
Published: August 2022

Ryanodine receptors (RyRs) exhibit dynamic arrangements in cardiomyocytes, and we previously showed that ‘dispersion’ of RyR clusters disrupts Ca2+ homeostasis during heart failure (HF) (Kolstad et al., eLife, 2018). Here, we investigated whether prolonged β-adrenergic stimulation, a hallmark of HF, promotes RyR cluster dispersion and examined the underlying mechanisms. We observed that treatment of healthy rat cardiomyocytes with isoproterenol for 1 hr triggered progressive fragmentation of RyR clusters. Pharmacological inhibition of Ca2+/calmodulin-dependent protein kinase II (CaMKII) reversed these effects, while cluster dispersion was reproduced by specific activation of CaMKII, and in mice with constitutively active Ser2814-RyR. A similar role of protein kinase A (PKA) in promoting RyR cluster fragmentation was established by employing PKA activation or inhibition. Progressive cluster dispersion was linked to declining Ca2+ spark fidelity and magnitude, and slowed release kinetics from Ca2+ propagation between more numerous RyR clusters. In healthy cells, this served to dampen the stimulatory actions of β-adrenergic stimulation over the longer term and protect against pro-arrhythmic Ca2+ waves. However, during HF, RyR dispersion was linked to impaired Ca2+ release. Thus, RyR localization and function are intimately linked via channel phosphorylation by both CaMKII and PKA, which, while finely tuned in healthy cardiomyocytes, underlies impaired cardiac function during pathology.
Locally adaptive temperature response of vegetative growth in Arabidopsis thaliana
Authors: Clauw Pieter , Kerdaffrec Envel , Gunis Joanna , Reichardt-Gomez Ilka , Nizhynska Viktoria , Koemeda Stefanie , Jez Jakub , Nordborg Magnus
Published: July 2022

We investigated early vegetative growth of natural Arabidopsis thaliana accessions in cold, nonfreezing temperatures, similar to temperatures these plants naturally encounter in fall at northern latitudes. We found that accessions from northern latitudes produced larger seedlings than accessions from southern latitudes, partly as a result of larger seed size. However, their subsequent vegetative growth when exposed to colder temperatures was slower. The difference was too large to be explained by random population differentiation, and is thus suggestive of local adaptation, a notion that is further supported by substantial transcriptome and metabolome changes in northern accessions. We hypothesize that the reduced growth of northern accessions is an adaptive response and a consequence of reallocating resources toward cold acclimation and winter survival.
Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome
Authors: Yildirim Murat , Delepine Chloe , Feldman Danielle , Pham Vincent A , Chou Stephanie , Ip Jacque , Nott Alexi , Tsai Li-Huei , Ming Guo-Li , So Peter TC , Sur Mriganka
Published: July 2022

Human cerebral organoids are unique in their development of progenitor-rich zones akin to ventricular zones from which neuronal progenitors differentiate and migrate radially. Analyses of cerebral organoids thus far have been performed in sectioned tissue or in superficial layers due to their high scattering properties. Here, we demonstrate label-free three-photon imaging of whole, uncleared intact organoids (~2 mm depth) to assess early events of early human brain development. Optimizing a custom-made three-photon microscope to image intact cerebral organoids generated from Rett Syndrome patients, we show defects in the ventricular zone volumetric structure of mutant organoids compared to isogenic control organoids. Long-term imaging live organoids reveals that shorter migration distances and slower migration speeds of mutant radially migrating neurons are associated with more tortuous trajectories. Our label-free imaging system constitutes a particularly useful platform for tracking normal and abnormal development in individual organoids, as well as for screening therapeutic molecules via intact organoid imaging.
Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression
Authors: Liu Qiangqiang , Luo Qian , Feng Jianyu , Zhao Yanping , Ma Biao , Cheng Hongcheng , Zhao Tian , Lei Hong , Mu Chenglong , Chen Linbo , Meng Yuanyuan , Zhang Jiaojiao , Long Yijia , Su Jingyi , Chen Guo , Li Yanjun , Hu Gang , Liao Xudong , Chen Quan , Zhu Yushan
Published: August 2022

DBC1 has been characterized as a key regulator of physiological and pathophysiological activities, such as DNA damage, senescence, and tumorigenesis. However, the mechanism by which the functional stability of DBC1 is regulated has yet to be elucidated. Here, we report that the ubiquitination-mediated degradation of DBC1 is regulated by the E3 ubiquitin ligase SIAH2 and deubiquitinase OTUD5 under hypoxic stress. Mechanistically, hypoxia promoted DBC1 to interact with SIAH2 but not OTUD5, resulting in the ubiquitination and subsequent degradation of DBC1 through the ubiquitin–proteasome pathway. SIAH2 knockout inhibited tumor cell proliferation and migration, which could be rescued by double knockout of SIAH2/CCAR2. Human tissue microarray analysis further revealed that the SIAH2/DBC1 axis was responsible for tumor progression under hypoxic stress. These findings define a key role of the hypoxia-mediated SIAH2-DBC1 pathway in the progression of human breast cancer and provide novel insights into the metastatic mechanism of breast cancer.
La confianza de Francisco de Goya: A la luz de tres perspectivas feministas
Authors: Burlando Bravo Giannina Leonora
Published: July 2022

Este ensayo describe una particular experiencia estética, basada en la obra gráfica La confianza, de Goya, perteneciente a la serie de los Caprichos e invenciones, que son paisajes de pesadilla que ilustran la crisis social de la época de las Luces. Desde aquí, desarrollaré una hermenéutica personal que avanza por tres escenarios teóricos sobre lo que implicaría la confianza de una mujer en otra, a partir del soporte de imagen. Las diversas tesis teóricas se sitúan en la órbita del pensamiento feminista de actualidad y en donde se representarán a tres autoras: Muraro, Despentes y Braidotti. Finalmente, este dispositivo de interpretación permitirá relevar el arte de Goya a propósito de una posible revisión de crítica social sobre la virtud de la confianza.
El Carnicero del Rey O el real método para el cultivo de la vida
Authors:   Universidad de Macau, Moeller Hans-Georg
Published: July 2022

Este ensayo sugiere una lectura alternativa del relato del “Cocinero Ding” en el Zhuangzi. Se arguye que esta famosa historia puede ser leída como una crítica del ritual y la política en la China antigua, así como del violento régimen de domesticación que ellas representaron. El relato invierte satíricamente la invisibilización ritual de la matanza de humanos y bestias, y parodia así el sadismo del “real método para el cultivo de la vida” al hacer que un carnicero realice la matanza ritual frente al gobernante y no a sus espaldas. El ensayo combina aproximaciones literarias, filosóficas y sinológicas en un esfuerzo por balancear la rigurosidad histórica con la relevancia filosófica.
Pornografía y redes sociales, espacios de intervención con jóvenes, ante la violencia sexual
Authors:   Facultad de Estudios Sociales y del Trabajo. Universidad de Málaga, Málaga (España), Arredondo Quijada Rafael , Olivares Alvarez Sara ,   Asociación Cívica para la Prevención (ACP), Málaga (España), Luna Cerezo Elvira ,   Asociación Cívica para la Prevención (ACP), Málaga (España)
Published: July 2022

En un contexto social en el que las plataformas de pornografía y las redes sociales son tan accesibles para los jóvenes y su control es tan escaso, se hace necesario analizar el impacto que esta accesibilidad tiene sobre su aprendizaje acerca de la conducta sexual, la manera de relacionarse con sus iguales y la vulnerabilidad ante la violencia sexual. Se lleva a cabo una investigación sobre los nuevos hábitos sexuales en la juventud a un total de 449 jóvenes, (47,7% hombres, 51,7% mujeres y un 0,6% otros). Los resultados muestran que un 78,6% ha consumido pornografía en alguna ocasión, siendo el género masculino el que más con un 56,7%, representando la edad de 12 años la que marca un mayor porcentaje (16,8%). Y en lo que refiere a obtener información sobre sexualidad, uno de cada tres entrevistados (33,4%), expresa que es a través de internet. A su vez un 31,5% de las mujeres indica haber tenido que bloquear a menudo su red social ante la insistencia para quedar. Estos datos evidencian como la utilización de pornografía y el uso de redes sociales se convierten en espacios prioritarios de intervención en lo que a la sexualidad refiere.
Inversión Social para la sostenibilidad: Aportes desde Urbanismo Social para la prevención del deterioro físico y social en nuevos barrios de interés social
Authors:   Fundación Urbanismo Social, Santiago (Chile), Monardes Morales Pía , Lowick-Russell Avalos Jenny ,   Fundación Urbanismo Social, Santiago (Chile), Carraha Molina Juan ,   Fundación Urbanismo Social, Santiago (Chile), Gallo Hernández Emilia ,   Fundación Urbanismo Social, Santiago (Chile)
Published: July 2022

A través de programas públicos de vivienda centrados en la entrega de subsidios a la demanda, el Estado Chileno se ha concentrado durante las últimas décadas en el desafío de reducir el déficit habitacional cuantitativo que afecta a la población más vulnerable del país. Esta estrategia obtuvo resultados positivos en términos de cobertura, sin embargo, el escaso énfasis en la calidad ha provocado que muchas familias abandonaran las viviendas y barrios tras poco tiempo de ocupación. La respuesta de programas como el Fondo Solidario de Elección de Vivienda, ha sido incorporar el acompañamiento social a las familias para fortalecer la construcción social de los nuevos barrios. Sin embargo, la inversión social no supera el 2% del total del proyecto, y descansa sobre indicadores de cumplimiento que no reflejan un real involucramiento de los beneficiarios. Frente a esto, Fundación Urbanismo Social desarrolló el Modelo de Urbanismo Social Preventivo, que busca prevenir el deterioro físico y social de los nuevos barrios de interés social, buscando que las personas se sientan felices en ellos a través del fortalecimiento de los vínculos comunitarios, las organizaciones sociales y la identidad territorial. Este artículo discute sus alcances y el resultado de su evaluación en el tiempo.
Evaluating the baseline auscultation abilities of second-year chiropractic students using simulated patients and high-fidelity manikin simulators: A pilot study
Authors: da Silva-Oolup Sophia A. , Giuliano Dominic , Stainsby Brynne , Thomas Joshua , Starmer David
Published: August 2022

Objective

To assess the ability of 2nd-year students to identify normal and abnormal findings during cardiac and lung auscultation using high-fidelity manikin simulators and standardized patients. A secondary objective was to assess students' perceived competence and confidence in their abilities.

Methods

This was a descriptive pilot study of randomly selected 2nd-year students at 1 chiropractic training program. Participants were asked to perform cardiac and lung auscultation on high-fidelity manikins (2 stations) and standardized human patients (2 stations) with normal and abnormal auscultation sounds. Participants described the auscultated sound as “abnormal” or “normal” and were also asked to score their confidence in describing the sound and competence in performing auscultation on a 100-mm visual analog scale. Descriptive statistics were calculated for all study variables.

Results

Thirty-two students (23 women and 9 men) were included. For lung auscultation, 15.6% were incorrect on the human subject and 6.2% were incorrect on the manikin. For cardiac auscultation, 62.5% were incorrect on the human subject and 40.6% were incorrect on the manikin. Confidence mean scores ranged from 34.8 to 60. Competence mean scores ranged from 34.8 to 50.

Conclusion

Results identified that 2nd-year students from 1 institution were correct in identifying an abnormal sound during lung auscultation but reported low levels of perceived competence or confidence in their responses. They performed poorly on cardiac auscultation and reported low perceived confidence and competence in their abilities to perform cardiac auscultation and identify sounds.
Vetiver Floating Wetlands for Dyeing Effluent
Authors: Aarthy M. , Banu K. Sara Parwin , Karthikeyan G. , Suganya K. , Haripriya S.
Published: August 2022

As a result of industrialization, the degree of global water contamination has drastically grown in recent decades. Both rich and developing nations are seeing this worldwide trend, although the later are experiencing it more pronouncedly. Due to its extraordinary and distinctive morphological and physiological characteristics, the Vetiver Floating Wetlands (VFWs), which is based on Vetiver grass (Chrysopogon zizanioides), has been successfully used as a phytoremediation tool to remediate both polluted water like municipal wastewater such as sewage effluent, landfill leachate, urban runoff, drainage channels, industrial wastewater such as food processing factories, and contaminated land (mine overburden and tailings, solid waste dumps). This study focuses on the use of hydroponics and floating wetlands to clean contaminated dyeing effluent. This study aims to find the efficiency of Vetiver Floating wetlands over various physio-chemical parameters in Dyeing effluent. The study was laid down in Tamil Nadu Agricultural University, Coimbatore in 2022 during the month of April- May. The effluent was diluted to different concentrations namely 25%, 50%, 75% and 100%. Various parameters were analyzed in these treatments in Dyeing effluent. The samples were collected at 15 days interval analyzed for one month. In Dyeing effluent, 50% concentration of the effluent showed better results over Vetiver Floating Wetlands and the removal efficiency was greater at this particular concentration.
Economics of Wet Seeded Rice as Influenced by Alternate Wetting and Drying Irrigation Regimes and Weed Management
Authors: Reddy N. Prathap , Sagar G. E. Ch. Vidya , Yakadri M. , Reddy M. Malla , Madhavi A. , Reddy S. Narender
Published: August 2022

An experiment was conducted at College Farm, Professor Jayashankar Telangana State Agricultural University, Rajendranagar, Hyderabad during rabi 2020-21 and 2021-22.The experiment was laid out in split plot design with two factors i.e., irrigation regimes (I1 : Farmers practice (continuous flooding of 2-5 cm from 3-4 days after sowing), I2: AWDI at 5 cm depletion of ponded water, I3: AWDI at 10 cm depletion of ponded water and I4: AWDI at 15 cm depletion of ponded water) and weed management practices (W1: Control (Unweeded check), W2: Pyrazosulfuron ethyl (10% WP) 20 g ha-1 PE fb Penoxsulam (1.02%) + Cyhalofop butyl (5.1%) 120 g ha-1 PoE, W3:Pyrazosulfuron ethyl (10% WP) 20 g ha-1 PE fb Penoxsulam (1.02%) + Cyhalofop butyl (5.1%) 120 g ha-1 PoE + Mechanical weeding at 45 DAS and W4: Weed free (Mechanical weeding at 15, 35 and 55 DAS with line weeding). Among the irrigation regimes, cost of cultivation and gross returns were highest in farmers practice (continuous flooding of 2-5 cm from 3-4 days after sowing) and lowest in AWDI at 15 cm depletion of ponded water. Net returns and B:C ratio was highest in AWDI at 5 cm depletion of ponded water and lowest net returns and B:C ratio  was recorded in AWDI at 15 cm depletion of ponded water. Among weed management practices highest cost of cultivation, gross returns were achieved in weed free (mechanical weeding at 15, 35 and 55 DAS with line weeding) and lowest cost of cultivation and gross returns was achieved in Control (unweeded control). With respective to herbicide application highest gross returns, net returns and B:C ratio were achieved in pyrazosulfuron ethyl (10% WP) 20 g ha-1 PE fb penoxsulam (1.02%) + cyhalofop butyl (5.1%) 120 g ha-1 PoE + mechanical weeding at 45 DAS.
Impact of Media Information in the Development of Novel Coronavirus Symptoms without the Disease: Nocebo Phenomenon
Authors: Hegde Vinanthi , Maheshbabu N.
Published: July 2022

Introduction: Nocebo works on the human belief system, believing that one can be infected with Covid can be understood by Nocebo.

Purpose:  The purpose of this research study was to see if the media showing coronavirus news can influence the development of covid-19 symptoms without the disease.

Methods: This study adopted a Qualitative Research Design. For this study, 9 participants were interviewed. Thematic analysis was used for coding the data.

Results: Results of the study indicated that fear threat was noticed throughout the pandemic which aroused anxiety in their life which also included, fear of infection, loss of loved ones, and inaccessibility to various things. This fear threat seems to be aroused from the constant media influence, and there are studies that support the results. 

Conclusion: The responses received from the participant indicated fear and anxiousness as major factor for developing the symptom.
Trends and Distribution of In-Hospital Mortality Among Pregnant and Postpartum Individuals by Pregnancy Period
Authors: Admon Lindsay K. , Ford Nicole D. , Ko Jean Y. , Ferre Cynthia , Kroelinger Charlan D. , Kozhimannil Katy B. , Kuklina Elena V.
Published: July 2022

This cross-sectional study investigates trends in death rates and proportion of deaths by pregnancy period among pregnant and postpartum individuals from 1994 to 2019.
A comparable truth baseline improves truth/lie discrimination
Authors: Bogaard Glynis , Nußbaum Madeleine , Schlaudt Laura Sophie , Meijer Ewout H. , Nahari Galit , Vrij Aldert
Published: July 2022

In a comparable truth baseline (CTB), a knowingly truthful baseline statement is compared to a statement of interest, and deviations in verbal details possibly indicate deceit. In two experiments, we investigated whether a CTB can improve truth/lie discrimination when verbal details are coded by independent raters (Experiment 1) and when judged by naive observers (Experiment 2). In addition, we investigated whether lie tellers would calibrate their lies to match the detailedness of their baseline. Results showed no evidence of calibration. As expected, truths were more detailed than their corresponding baselines, while lies were less detailed. Significant differences emerged for spatial, visual and action details. Experiment 2 did not show that a CTB improved observers' lie detection accuracy. Taken together, our results showed that a deviation in details from a CTB may serve as a helpful aid in lie detection.
AMA survey finds patients want their medical information private
Authors: Knopf Alison
Published: July 2022

The eroding confidentiality of medical information—all of it, not just that relating to substance use disorders (SUDs)—is a major concern of patients, a survey by the American Medical Association (AMA) has found.
Precisely Targeted Nano‐Controller of PD‐L1 Level for Non‐Small Cell Lung Cancer Spinal Metastasis Immunotherapy
Authors: Zhou Lei , Liang Haifeng , Ge Yuxiang , Ding Wang , Chen Qing , Zhang Taiwei , Xiao Lan , Li Yulin , Dong Jian , He Xiaowen , Xue Fengfeng , Jiang Libo
Published: July 2022

Although immune checkpoint inhibitors (ICIs) have been widely applied to treat non‐small cell lung cancer (NSCLC), a significant proportion of patients, especially those with spinal metastasis (NSCLC‐SM), are insensitive to anti‐programmed death 1 (PD‐1)/programmed death ligand 1 (PD‐L1) ICIs. A drug delivery nano‐controller of PD‐L1 that targets NSCLC‐SM can solve this problem, however, none have been developed to date. In this study, it is shown that integrin β3 (β3‐int) is strongly upregulated in NSCLC‐SM. Its inhibitor RGDyK promotes PD‐L1 ubiquitination, indicating the potential application of RGDyK as a new PD‐L1 inhibitor in nano‐controller and a targeting peptide for NSCLC‐SM treatment. According to the synergistic effect of photodynamic therapy and ICIs on T‐cell activation through the release of tumor antigens, RGDyK‐modified and zinc protoporphyrin (ZnPP)‐loaded mesoporous silicon nanoparticles (ZnPP@MSN‐RGDyK) are fabricated. The ZnPP@MSN‐RGDyK nanoparticles precisely target β3‐int to inhibit PD‐L1, exhibiting high photodynamic therapy efficiency, and excellent immunotherapeutic effects in an NSCLC‐SM mouse model. Collectively, the findings indicate that ZnPP@MSN‐RGDyK is a promising immunotherapeutic agent for treating NSCLC‐SM.
Highly Orientated Perovskite Quantum Dot Solids for Efficient Solar Cells
Authors: Chen Jingxuan , Jia Donglin , Zhuang Rongshan , Hua Yong , Zhang Xiaoliang
Published: July 2022

Perovskite quantum dots (PQDs) have emerged as competitive optoelectronic materials for photovoltaic applications due to their ideal bandgap energy, high defect tolerance, and solution processability. However, the highly dynamic surface and imperfect cubic structure of PQDs generally result in unfavorable charge‐carrier transport within the PQD solids and serious nonradiative recombination. Herein, a highly orientated PQD solid is demonstrated using precursor engineering accompanied by a chemical stripping treatment (CST). A combination of systematic experimental studies and theoretical calculations is conducted to fundamentally understand the resurfacing of PQDs using the CST approach. The results reveal that the highly ordered PQDs can result in a high orientation of PQD solids, significantly promoting charge‐carrier transport within the PQD solids. Meanwhile, the ideal cubic‐structured PQD with an iodine‐rich surface dramatically decreases surface trap states, thereby substantially diminishing trap‐assisted nonradiative recombination. Consequently, the inorganic PQD solar cell delivers a power conversion efficiency of up to 16.25%. This work provides a feasible avenue to construct highly orientated PQD solids with improved photophysical properties for high‐performance optoelectronic devices.
All‐In‐One Integrated Multifunctional Broadband Metasurface for Analogue Signal Processing, Polarization Conversion, Beam Manipulation, and Near‐Field Sensing
Authors: Liu Baiyang , Du Jiachen , Jiang Xiaonan , Li Yin , Wong Sai‐Wai , Cheng Qiang , Cui Tie Jun , Zhang Qingfeng
Published: July 2022

Programmable metasurface, or reconfigurable intelligent surface is one of the most promising strategies to enhance communication and sensing capacities via arrays of reconfigurable meta‐atoms. The functionalities of conventional programmable metasurfaces are usually limited, and active meta‐atoms are connected with steering‐logic board through cables, which makes the whole system inconvenient for installation and stable use. Here an all‐in‐one integrated multifunctional metasurface for various application purpose is proposed. The integration of metasurface and steering‐logic board produces an all‐in‐one system, which makes it compact, low profile, and stable. The novel meta‐atom structure provides all‐in‐one functionalities, including 1) dispersion‐reconfigurable spatial phaser for analogue signal processing, 2) polarization conversion, 3) beam steering and orbital angular momentum generation for high‐speed communication and, 4) near‐field scanning for sensing. The proposed metasurface also has a broadband property, which is operating from 9.5 to 10.5 GHz with 10% relative bandwidth. Such a design integrates functionalities of signal processing, communication, and sensing in a single programmable metasurface, which makes it especially useful for integrated sensing and communication toward next‐generation wireless networks.
Regio‐ and Stereospecific Desulfinylative Chlorination of Spiroaziridine Oxindoles at Spiro‐Center for Formal [3+2]‐Cycloaddition with CS2: Sequential One‐Pot Synthesis of (−)‐Spirobrassinin
Authors: Biswas Anurag , Hajra Saumen
Published: July 2022

A regioselective and stereocontrolled strategy affording spirothiazolidine‐2‐thiones with enantiopurity of 90 to >99% ee has been developed via formal [3+2]‐ cycloaddition of CS2 and 3‐(aminomethyl)‐3‐chloro‐indolin‐2‐one, synthesized in situ by desulfinylative chlorination of N‐tert‐butylsulfinyl spiroaziridine oxindoles. The protocol has been further utilized in the sequential one‐pot gram‐scale synthesis of enantiopure (−)‐spirobrassinin (>99% ee), a cruciferous phytoalexin with diverse biological activities.

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Over 15% Efficiency PbS Quantum‐Dot Solar Cells by Synergistic Effects of Three Interface Engineering: Reducing Nonradiative Recombination and Balancing Charge Carrier Extraction
Authors: Ding Chao , Wang Dandan , Liu Dong , Li Hua , Li Yusheng , Hayase Shuzi , Sogabe Tomah , Masuda Taizo , Zhou Yong , Yao Yingfang , Zou Zhigang , Wang Ruixiang , Shen Qing
Published: July 2022

Lead sulfide colloidal quantum dot solar cells (CQDSCs), the next generation of photovoltaics, are hampered by non‐radiative recombination induced by defects and an electron‐hole extraction imbalance. CQDSCs have three interfaces: CQD/CQD, electron transport layer (ETL)/CQD, and CQD/hole transport layer (HTL), and modifying one of these interfaces does not fix the problem stated above. Here, coordinated control and passivation of the three interfaces in PbS CQDSCs are presented and it is shown that the synergistic effects may improve charge transport and charge carrier extraction balance and minimize non‐radiative recombination simultaneously. A facile method is developed for epitaxially growing an ultrathin perovskite shell on the CQD surface to passivate the CQD/CQD interface, resulting in CQD absorber layers with long carrier diffusion lengths. With the introduction of organic films with adjustable electrical characteristics, the influence of ETL/CQD interfacial modifications on carrier transport and recombination is investigated. An excessive increase in the electron extraction rate reduces the fill factor and solar efficiency, as discovered. Therefore a modified layer is created at the CQD/HTL interface to promote hole extraction, which enhances charge extraction balance and passivates the interface. Finally, PbS CQDSCs exhibit a power conversion efficiency of 15.45%, a record for Pb chalcogenide CQDSCs.
Net global warming potential and greenhouse gas intensity in organic and conventional wheat‐based farming systems
Authors: Sainju Upendra M. , Hatfield Patrick G. , Ragen Devon
Published: July 2022

There is a need of information about global warming potential in wheat (Triticum aestivum L.)‐based organic and conventional farming systems. We evaluated net global warming potential (NGWP) and greenhouse gas intensity (GHGI) in the organic farming system (OFS) using sheep grazing to control weeds without N application and the conventional farming system (CFS) with herbicide, pesticide, and N applications in three crop phases of a 5‐yr crop rotation from 2013–2014 to 2015–2016 in the northern Great Plains. Crop phases were winter wheat after lentil (Lens culinaris L.) (W‐L), winter wheat after sweet clover (Melilotus officinalis L.) cover crop (W‐C), and lentil after winter wheat (L‐W) in a 5‐yr rotation of safflower (Carthamus tinctorius L.) and sweet clover cover crop intercrop–sweet clover cover crop–winter wheat–lentil–winter wheat. Carbon sequestration rate at the 0‐to‐120‐cm depth from 2009 to 2015 was greater in OFS with W‐C than other treatments. The CO2 equivalent of N2O + CH4 fluxes was greater in OFS with L‐W than other treatments, except in CFS with L‐W in 2014–2015 and 2015–2016. The CO2 equivalent of N fertilization was greater in CFS, but CO2 equivalent of CH4 flux due to enteric fermentation from sheep was greater in OFS. Both NGWP and GHGI were lower in OFS with W‐C than other treatments. Organic farming system using sheep grazing to manage weeds in winter wheat following cover crop can reduce NGWP and GHGI compared with CFS with chemical inputs in dryland farming.
Multivariate and multiharvesting trial for agronomic traits in the genetic resources of guineagrass
Authors: Carvajal‐Tapia Juliana Isabel , Vivas‐Quila Nelson Jose , Barahona Rolando , Sandoval Burbano Karol Michelle , Castiblanco Valheria
Published: July 2022

The diversity and use of forages and grasslands for animal feeding are essential in tropical livestock systems. Seasonal changes are mainly marked by variations in precipitation patterns. Grasslands are managed as perennial crops and therefore must be resilient to tolerate both dry and rainy seasons. The integration of animal production with the genetic aspects of forages is important for helping to identify resilient alternatives for sustainability in livestock systems. This study developed a multivariate and multiharvesting trial (MHT) for plant height, green forage weight (GFW), and dry matter yield (DMY) in a diversity panel of 130 accessions of guineagrass [Megathyrsus maximus (Jacq.) B.K. Simon & S.W.L. Jacobs] established in the Patía Valley of Colombia. Our study aims to identify interactions among weather conditions and different genotypes for agronomic variables as well as identify outstanding accessions for their productivity and adaptability. The entry mean heritability values were .88, .47, and .39 for the traits plant height, GFW, and DMY, respectively. The genetic correlations among different harvests ranged .5–.9 for plant height and .2–.9 for GFW. Heritability and genetic correlations suggest that plant height and yield are largely influenced by plant genetic effects. The correlation among plant height and yield was .42 for GFW and .33 for DMY. Negative correlations were not found in the agronomic behavior of the materials among the harvests under rainy and dry conditions. The MHT analyzed under the methodology of factor analysis revealed that accessions 16062 and 6982 stood out consistently for plant height, GFW, and DMY across different harvests. These findings strengthen processes in the search for resilient forages in the transition toward eco‐efficient livestock production and provide knowledge on which agronomic variables and forage materials to select, according to criteria of interest to both producers and plant breeders.
Exergoenvironmental damages assessment in a desert‐based agricultural system: A case study of date production
Authors: Hesampour Reza , Hassani Mehrdad , Yildizhan Hasan , Failla Sabina , Gorjian Shiva
Published: July 2022

Developing countries, especially those in hot and dry areas, need more attention to achieve sustainable development as they apply excessive inputs in production processes. The present study aims to quantify the amount of environmental emissions and determine the most appropriate pattern of energy use in the date (Phoenix dactylifera L.) production process using thermodynamic analysis. The information was gathered through questionnaires and face‐to‐face interviews. From the results, cumulative exergy and energy demand for one Mg of date fruit production were calculated as 697 and 1640 MJ, respectively. Carbon dioxide emission was also measured at 197 kg Mg–1. Moreover, cumulative exergy consumption illustrated that manure and diesel fuel consumption is high, though diesel fuel and N consumption are given the most cumulative energy demand. Renewability indicator, cumulative degree of perfection, and the recoverable exergy ratio value of the date fruit production process were calculated as 0.62, 2.68, and 4.32, respectively. The date's chemical exergy value was calculated to be 14.96 MJ kg–1. Dates have a high chemical exergy value because of their high carbohydrate content and low water content. As a result, crop chemical combinations have a direct impact on the production process. The total direct greenhouse gas emissions induced by the inputs consumption were 310.02 kg Mg–1. Emissions to air, soil, and water were 308.76, 5.60 × 10−1 and 6.96 × 10−1 kg Mg–1. In general, date production in Khuzestan province is partially renewable.
Eine sp‐Kohlenstoffhaltige Leitfähige Metallorganische Gerüstverbindung als Photokathode für die Photoelektrochemische Wasserstoffentwicklung
Authors: Lu Yang , Zhong Haixia , Li Jian , Dominic Anna Maria , Hu Yiming , Gao Zhen , Jiao Yalong , Wu Mingjian , Qi Haoyuan , Huang Chuanhui , Wayment Lacey J. , Kaiser Ute , Spiecker Erdmann , Weidinger Inez M. , Zhang Wei , Feng Xinliang , Dong Renhao
Published: July 2022

Metallorganische Gerüstverbindungen (englisch metal–organic frameworks, MOFs) sind aufgrund ihrer hohen Porosität von großem Interesse für eine Vielzahl von Anwendungen in der Katalyse und Gastrennung. Eine begrenzte Anzahl an aktiven Zentren sowie das Verhalten als elektrischer Isolator machen den Einsatz von MOFs als aktives Photokathodenmaterial für die photoelektrokatalytische Wasserstoffproduktion allerdings nicht möglich. Wir berichten hiermit von der Entwicklung eines gestapelten, leitfähigen, zweidimensional‐konjugierten MOFs (englisch 2D conjugated MOF, 2D c‐MOF) welches aktive sp‐Kohlenstoffzentren enthält. Der MOF Cu3HHAE2 basiert auf einem makrozyklischen Aryl‐Alkin Liganden, welcher via CuO4 Einheiten verknüpft ist. Dieser sp‐Kohlenstoff haltige 2D c‐MOF zeigt Halbleitereigenschaften und eine breite Absorption bis in den nah‐infraroten Bereich (1600 nm). Erstmalig kann dank der hohen Anzahl an Dreifachbindungen Cu3HHAE2 als MOF‐Photokathode für die photoelektrochemische (PEC) Wasserstoffentwicklung verwendet werden. Verglichen mit anderen strukturell definierten, co‐Katalysator freien organischen Photokathoden, zeigt er eine Rekordphotostromdichte für die Wasserstoffentwicklung von ≈260 μA cm−2 bei 0 V gegen die reversible Wasserstoffelektrode (englisch reversible hydrogen electrode RHE).