bluuebunny/crossref_metadata_2025 huggingface dataset:
Surgical Adverse Events for Primary Tumors of the Spine and Their Impact on Outcomes: An Observational Study From the Primary Tumors Research and Outcomes Network
Authors: Laflamme Mathieu , Gasbarrini Alessandro , Rhines Laurence D. , Lazary Aron , Gokaslan Ziya L. , Reynolds Jeremy J. , Luzzati Alessandro , Disch Alexander C. , Chou Dean , Clarke Michelle J. , Wei Feng , Bettegowda Chetan , Rampersaud Y. Raja , Boriani Stefano , Shin John H. , Lord Elizabeth , Sciubba Daniel M. , Laufer Ilya , Sahgal Arjun , Fisher Charles G. , Dea Nicolas ,   on behalf of the AO Spine Knowledge Forum Tumor
Published: February 2025

BACKGROUND AND OBJECTIVES:

Aggressive resection for primary tumors of the spine are associated with a high rate of adverse events (AEs), but the impact of AEs on patient-reported outcomes (PROs) remains unknown and is critical to the shared decision-making. Our primary objective was to assess the impact of surgical AEs on PROs using an international registry. Assessing the impact on clinical outcomes and identifying risk factors for AEs were our secondary objectives.

METHODS:

Patients who underwent surgery for a primary spinal tumor were selected through the Primary Tumor Research and Outcomes Network. Our primary outcome was the impact of AEs on PROs at 3 and 12 months after surgery (measured with Spinal Oncology Study Group Outcomes Questionnaire, Short-Form 36, and EuroQol 5 Dimension). We also assessed the impact on clinical outcomes (local control, surgical margins, readmission, reoperation, and mortality). We stratified our results according to severity of AEs, histology, and type of resection.

RESULTS:

374 patients met inclusion criteria (219 males/155 females). The mean age of the cohort was 48.7 years. The most frequent histology was chordoma (37.3%) followed by chondrosarcoma (8.8%). Sixty-seven patients (17.9%) experienced at least 1 intraoperative AE and 117 patients (31.3%) had at least 1 postoperative AE within 3 months. Overall, 159 patients (42.5%) experienced AEs. The readmission rate was significantly higher in patients who experienced AEs (Any AE: 10.1% vs no AE: 1.9% within 3 months; P = <0.001). PROs were not significantly affected by AEs in most questionnaires. Local control, risk of reoperation, mortality, and achieving preplanned margins were similar between AE groups.

CONCLUSION:

The rate of surgical AEs is considerable in this population. Surgical AEs seem to be associated with a higher number of readmissions, but do not seem to result in significant differences in PROs or in a higher risk of reoperation, mortality, and failure to achieve preplanned margins.
Amyloid-β can activate JNK signalling via WNT5A-ROR2 to reduce synapse formation in Alzheimer's disease
Authors: Fang Kevin , Pishva Ehsan , Piers Thomas , Scholpp Steffen
Published: February 2025

Wnt signalling is an essential signalling system in neurogenesis, with a crucial role in synaptic plasticity and neuronal survival, processes that are disrupted in Alzheimer's disease (AD). Within this network, the Wnt/β-catenin pathway has been studied for its neuroprotective role, and this is suppressed in AD. However, the involvement of the non-canonical Wnt-planar cell polarity (Wnt/PCP) pathway in AD remains to be determined.

This study investigates the role of ROR2, a Wnt/PCP co-receptor, in synaptogenesis. We demonstrate that WNT5A-ROR2 signalling activates the JNK pathway, leading to synapse loss in mature neurons. This effect mirrors the synaptotoxic actions of Aβ1-42 and DKK1, which are elevated in AD. Notably, blocking ROR2 and JNK mitigates Aβ1-42 and DKK1-induced synapse loss, suggesting their dependence on ROR2. In induced pluripotent stem cell (iPSC)-derived cortical neurons carrying a PSEN1 mutation, known to increase the Aβ42/40 ratio, we observed increased WNT5A-ROR2 clustering and reduced numbers of synapses. Inhibiting ROR2 or JNK partially rescued synaptogenesis in these neurons. These findings suggest that, unlike the Wnt/β-catenin pathway, the Wnt/PCP-ROR2 signalling pathway can operate in a feedback loop with Aβ1-42 to enhance JNK signalling and contribute to synapse loss in AD.
Policy Brief 14: Targeting unexplained wealth: Implications of the EU’s 2024 Directive on asset recovery
Authors: Dornbierer Andrew
Published: February 2025

The European Union’s 2024 Directive on Asset Recovery and Confiscation obliges Member States to, among other things, introduce legislative measures to enable the confiscation of “unexplained wealth”.
This policy paper examines Article 16, which contains this obligation, and the powers and restrictions that Member States will need to include in such “unexplained wealth” measures to ensure compliance with the Directive.
In brief, the Directive gives legislators in EU Member States flexibility to decide the scope of their own unexplained wealth measures. At a minimum, they must introduce measures that can be used to target unexplained wealth linked to organised crime.
Member States could, however, adopt broader measures that target unexplained wealth relating to all criminal activity, including corruption.
About this Policy Brief
This publication is part of the Basel Institute on Governance Policy Brief series, ISSN 2624-9669.
You may freely share or republish it under a Creative Commons BY-NC-ND 4.0 licence. Suggested citation: Dornbierer, Andrew. 2024. ‘Targeting unexplained wealth: Implications of the EU’s 2024 Directive on asset recovery.’ Policy Brief 14, Basel Institute on Governance. Available at: baselgovernance.org/pb-14. 
This is a publication of the International Centre for Asset Recovery (ICAR) at the Basel Institute on Governance. ICAR receives core funding from the Governments of Jersey, Liechtenstein, Norway, Switzerland and the UK.
Mapping the evidence on patient-centred outcome measures used in orphan medicinal product reimbursement frameworks: Protocol for a scoping review
Authors: Sangalang Stephanie , Collins Stack Lucy , McGrath Vicky , Pellegrini Mariangela , Somanadhan Suja
Published: February 2025

Background Patient-centered outcome measures (PCOMs) are tools designed to integrate patient perspectives by focusing on outcomes that matter the most to patients. Their importance is pronounced in rare diseases where patients face unique challenges. PCOMs and Orphan Medicinal Product (OMP) reimbursement frameworks are critical for addressing the challenges of rare diseases. Their integration helps ensure that treatments meet patient needs, while being accessible and economically sustainable. This scoping review aims to explore the evidence available on the relationship between PCOMs and OMP reimbursement frameworks. Methods This scoping review will adhere to the Preferred Reporting Items of Systematic Reviews extension for Scoping Review (PRISMA-ScR) and Joanna Briggs Institute guidelines, utilizing a structured six-step framework: (1) defining the research question, (2) locating relevant studies, (3) selecting studies, (4) extracting and organizing data, (5) synthesizing, summarizing, and presenting findings, and (6) engaging in consultation with knowledge users. Inclusion criteria were determined using the population-conceptual-context (PCC) framework. Searches will be conducted in CINAHL, Embase, MEDLINE (via PubMed), PsycINFO, SCOPUS, and the Web of Science. Grey literature will also be explored. Two reviewers will screen the titles and abstracts of the identified studies using a dual review process to ensure rigorous selection of relevant articles. The patterns, advances, gaps, evidence for practice, and research recommendation (PAGER) framework will be applied to summarize the findings. A panel of patient and public involvement (PPI) representatives will be engaged to validate the results and ensure alignment with patient-centered perspectives. Results The results will be reported according to the PRISMA-ScR checklist. Conclusions This scoping review will provide a comprehensive overview of the existing evidence on the relationship between PCOMs and OMP reimbursement frameworks. The findings have the potential to inform policy decisions, shape future research, and enhance the integration of patient-centered perspectives in reimbursement frameworks.
A pilot study to explore utility of electronic informed consent in a low- income setting; the case of a Controlled human infection study in Blantyre, Malawi
Authors: Ngoliwa Clara , Chakwiya Chikondi , Gondwe Joel , Nsomba Edna , Nkhoma Vitumbiko , Reuben Modesta , Chantunga Linda , Liwonde Pemphero , Mangani Edward , Kudowa Evaristar , Makhaza Lumbani , Toto Neema , Sochera Tiferanji , Chikaonda Tarsizio , Morton Ben , Henrion Marc Y.R. , Dula Dingase , Gordon Stephen B. , Chirwa Anthony E.
Published: February 2025

Background Electronic informed consent can improve accuracy, workflow, and overall patient experience in clinical research but has not been used in Malawi, owing to uncertainty about availability, utility, patient data security and technical support. Objectives We aimed to explore the utility of electronic consent (e-consent) in an ongoing human infection study in Blantyre, Malawi. Methods The approved paper consent forms were digitized using Open Data Kit (ODK). Following participant information giving by the research staff, healthy literate adult participants with no audio-visual impairments completed a self-administered e-consent and provided an electronic signature. We dual-consented participants by both paper-based and electronic-consenting. Signed e-consent forms were uploaded to a secure study server. Utility of e-consenting was observed by participation rate, user-friendliness, documentation error rate, and staff perception of the overall consenting process. Results All 109 participants offered e-consenting accepted participation. E-consenting was user-friendly, had no identifiable documentation errors as compared to 43.1% (n 47/109) error rate with paper-based consenting, and ensured data safety, and unravelled areas for consideration. Challenges with e-consenting included difficult digitization of ethics stamped documents, as well as present but infrequent delays of retrieval of e-consent forms. Conclusion E-consenting is feasible, has a utility benefit in a controlled human infection study in Malawi; a low-income country, and can supplement paper-based consenting. Its usefulness can improve the consenting process in research conducted in such settings. Additionally, success of e-consenting requires a careful consideration.
Non-trivial uses of melatonin: Its effects on sleep, jet lag, obesity, migraine, and gastrointestinal disorders
Authors: Wirkijowski Jakub , Wirkijowska Małgorzata , Mędyk Jolanta , Patarocha Yauheniya , Rogulski Michał , Ślusarska Aleksandra , Błasiak Paulina , Mikołajec Patryk , Huk Ruslan , Bilecka Barbara
Published: February 2025

Introduction and aim of the study: Melatonin consumption is steadily increasing. In this literature review, the authors intended to introduce the latest scientific evidence on the influence of the sleep hormone not only on the quality of time spent in bed and jet lag, but also to consider possible other positive impacts. Its eventual effects on headaches, gastrointestinal complaints, or obesity were analyzed.
Materials and methods: The authors searched the scientific literature utilizing search engines such as Science Direct, Cochrane, PubMed, Google Scholar, and UpToDate. The literature review focused on the association of melatonin with issues such as sleep, migraines, GERD, IBS, and jet lag.
Results: Most of the articles reviewed in this study highlighted the positive effects of melatonin supplementation on sleep problems and jet lag. Furthermore, many studies report that it likewise has a beneficial impact on conditions not directly related to sleep, such as obesity, GERD, IBS, or migraine. Nevertheless, the articles emphasize the need for further research to establish treatment protocols and to select an optimal dose.
Acne Vulgaris Management: A Review of First-Line and Advanced Pharmacological Treatments
Authors: Dobrzeniecki Krzysztof , Zygmunt Anna , Karoń Karolina , Karoń Łukasz , Karnas-Bogacka Patrycja
Published: February 2025

Introduction and objective: Acne vulgaris is a common chronic inflammatory skin disease affecting hair and sebaceous follicles, characterized by skin lesions most commonly appearing on the face. Several factors predispose individuals to the development of acne, including hormonal imbalances, genetic predisposition, and the use of certain medications. This review aims to evaluate and summarize first-line and advanced pharmacological treatments for acne vulgaris, highlighting their efficacy, safety, and emerging therapies for optimal management.
Review methods: The literature review utilized databases covering sources from PubMed, Google Scholar, Scopus, and Web of Science using the search terms encompassing the following keywords: ‘acne vulgaris’ and ‘topical retinoid therapy’, ‘benzoyl peroxide’, ‘azelaic acid’, ‘topical antibiotics’, ‘oral antibiotics’, ‘contraceptive agents’, ‘antiandrogen therapy’, ‘isotretinoin’.
Brief description of the state of knowledge: Current treatment methods range from topical therapies (i.e. antibiotics and retinoids) for mild cases to systemic medications (i.e. antibiotics, retinoids, and hormonal) for moderate to severe acne. In most cases, treatment should start with topical therapy.
Summary: Early intervention is crucial to mitigate the risk of scarring and psychosocial consequences. Emerging therapeutic strategies have the potential to enhance treatment outcomes.
The Potential of Antibodies Against the Phosphatidylserine / Prothrombin Complex as a Biomarker in Antiphospholipid Syndrome
Authors: Pasek Piotr , Czyż Witold , Kulbacka Julia , Kacperczyk Julia , Chuncia-Ileczko Marta , Wójcikiewicz Michalina , Arczewski Filip , Dziedzic Karol , Wojszczyk Maciej , Zys Damian , Ryniecka Julia
Published: February 2025

Introduction
Antibodies against the phosphatidylserine/prothrombin complex aPS/PT are autoantibodies recognizing an epitope formed in the phosphatidylserine/prothrombin complex as a result of conformational changes resulting from the combination and not present in any of the initial components of the complex. Its presence is predominantly observed in patients with thrombotic complications, particularly in those suffering from antiphospholipid syndrome (APS), systemic lupus erythematosus (SLE), and other connective tissue disorders. The new epitope is clinically relevant, as it plays a role in the mechanism and effects of autoantibody binding to phospholipids and their cofactors. Testing for aPS/PT, in conjunction with other APS markers, is recommended to assess the risk of thrombotic events.
Purpose
The object of this review is to assess whether aPS/PT complex serves as an effective diagnostic marker in the pathogenesis of complications associated with APS and other connective tissue disorders.
Material and methods
This review evaluates data from medical databases such as PubMed, NCBI or BMJ using the search term ‘aPS/PT’.
Conclusion
The presence of aPS/PT may be considered an independent risk factor for thrombosis. However, further research is needed to fully validate its clinical relevance in various clinical scenarios.
Selected aspects of parenthood in the perception of men – Part I
Authors: Kulmaczewska Magdalena Anna , Krajewska-Kułak Elżbieta , Kułak-Bejda Agnieszka , Bejda Grzegorz , Waszkiewicz Napoleon , Van Damme-Ostapowicz Katarzyna , Rysiak Edyta
Published: February 2025

Aim. The aim was to investigate the attitudes of men who plan to become fathers or not, and who either attend antenatal classes with their wife/partner or do not.
Material and methods. The study included three groups of 200 men: I – those who did not plan to become a father within the next year, II – those who were going to become fathers within the next year but did not attend antenatal classes, III – those who were gping to become fathers within the next year and attended antenatal classes. The original questionnaires were used.
Results. Pregnancy should be planned according to 81.8% of respondents. When it comes to 87.2% of men, they reported that man should support pregnant wife/partner, while 65.5% believed that joint visits to the doctor were pointless. Respondents most often preferred interactions between mother and father with the future child in her womb, such as stroking the belly (43% vs. 29.8%) and talking to the baby (31% vs. 19.8%).
Conclusions. Most men reported pregnancy should be planned. Men had problems with declaring whether the father should be on paternity leave after the birth, and there was no infl uence of the duration of the marriage, the fact of having children, the age of the respondents and education, and the place of residence had infl uence on the above.

Key words: pregnancy, attitudes, men
INGRESSAR NA CARREIRA DOCENTE E OS DESAFIOS DE TORNAR-SE PROFESSOR ALFABETIZADOR
Authors: Santos Livia Nayara Silva , Ferreira Edith Maria Batista
Published: February 2025

Este artigo é resultado de uma pesquisa realizada para a conclusão do curso de Pedagogia, da Universidade Federal do Maranhão (UFMA), durante o segundo semestre de 2023, com o objetivo de analisar as dificuldades enfrentadas pelos professores alfabetizadores iniciantes na docência, que participam do Programa “Alfabetizar Pra Valer”, no município de Urbano Santos, Maranhão. A metodologia utilizada se ancorou na abordagem qualitativa. Para a geração dos dados, fez-se uso da técnica de grupo focal, realizando encontros via Google meet, durante o período de 23 a 27/06/2023, com a participação de seis professores alfabetizadores ingressantes na docência. Os resultados apontaram que a iniciação à docência é uma fase desafiadora, uma vez que exige conciliar aprender a ensinar e ensinar ao mesmo tempo.
MARIA JOSÉ ARAÚJO MOUTA
Authors: Costa Maria Aparecida Alves da , Vasconcelos Cyntia Maria Silva , Guimarães Marília Duarte
Published: February 2025

O texto trata da biografia de Maria José Araújo Mouta, doravante Mazé Mouta, professora que atuou por 25 anos em escolas estaduais na periferia de Fortaleza, especificamente no bairro Conjunto Esperança. Partindo dessa base, o objetivo é compreender a formação e a prática docente de Mazé Mouta na periferia de Fortaleza-Ce. A pesquisa está amparada nos pressupostos teóricos da História Cultural e metodologicamente na História Oral, na qual a narrativa da professora foi a principal fonte de análise para o desenvolvimento de sua história de vida. Os resultados apontam que Mazé Mouta nasceu na região norte do Ceará, na cidade de Massapê, escolarizou-se ainda em casa com os ensinamentos de sua mãe e posteriormente estudou em escolas estaduais, assim como em particulares através da Campanha Nacional de Escolas da Comunidade (CNEC), onde concluiu o Ensino Pedagógico. Ainda, é possível ressaltarmos que sua prática educativa iniciou em escolas de Massapê e posteriormente migrou-se para Fortaleza dedicando-se a escolas de ensino fundamental e médio, na periferia de Fortaleza, atuando principalmente na gestão da Escola Adélia Brasil Feijó no bairro Conjunto Esperança.
Mathematical Modelling: Transforming Concepts Into Reality
Authors: Sahlot Simran , Arora Geeta
Published: February 2025

Mathematical modelling is a powerful tool that bridges the gap between theoretical concepts and real-world phenomena. It involves the development of mathematical equations, algorithms, and computational techniques to describe, analyse, and predict complex systems across various disciplines. Researchers are creating mathematical models based on actual events to meet the demands of this scientific era. The main aim of mathematical modelling is to gain understanding into complex systems, make predictions, and optimize processes. By using mathematical equations, scientists and researchers can simulate and analyse various scenarios, explore the effects of different parameters, and make informed decisions. Mathematical models can provide a better understanding of the given mechanisms governing the system and help uncover relationships and patterns that may not be immediately apparent. Policymakers use mathematical models to inform their choices when deciding on public health interventions like lockdowns, social isolation tactics, and vaccination rollout plans.
EL INCESTO Y EL (HOMO)EROTISMO GÓTICO: UNA PRÁCTICA SEXUAL Y UNA ESTÉTICA INCÓMODAS Y RARAS EN LA HOMOPOÉTICA MASCULINA COSTARRICENSE
Authors: Campos López Ronald
Published: February 2025

En este artículo se analiza hermenéuticamente, por un lado, la deconstrucción del incesto como prohibición, con base en dos poemas de Ioan Vidal (1960) y Gustavo Arroyo (2018). En estos textos, los actantes líricos enuncian, viven y defienden con naturalidad el incesto y el homoerotismo. Estos les permiten desarticular restricciones sociales, morales o familiares, a fin de establecer una relación sexual y existencial más libre y gozosa. Por otro lado, se propone el concepto de (homo)erotismo gótico y su perspectiva pornosatánica. Se estudian con base en poemas de Luis Antonio Bedoya (2015) y Roberto André Acuña Vargas (2022). Esta estética polemiza tabúes como la aparente monstruosidad, patologización o degeneración moral o espiritual de los sujetos homosexuales, hombres que tienen relaciones sexoafectivas con otros hombres y aun intersexuales, con el propósito de girar estos significados y afirmar literaria y políticamente el conocimiento profundo y revitalización emocional del erotismo o amor intermasculino.
NOTE E SPUNTI A PROPOSITO DI CALVINO E LA PSICOANALISI
Authors: Lussana Stefano
Published: February 2025

L’intervento prende le mosse dalla biblioteca dell’autore che contiene due scaffali di libri di psicoanalisi. A questo riguardo si elaborano alcune considerazioni sul rapporto esistente tra le opere dello scrittore e le influenze reciproche con il mondo analitico. Successivamente viene posta l’attenzione su Le città invisibili, un onirigramma che può rappresentare una metafora dell’inconscio creata dall’immaginazione infinita dell’autore.
SCRITTI IN VIAGGIO: DAL DIARIO AMERICANO AL REPORTAGE CINEMATOGRAFICO DI ITALO CALVINO
Authors: Ciancamerla Giulio
Published: February 2025

A partire dal 1959 il rapporto di Italo Calvino con gli Stati Uniti si arricchisce di nuove implicazioni: l’intensa passione giovanile per i film hollywoodiani, l’attenzione verso gli autori americani e l’osservazione della politica oltreoceano si combinano con una “immediata reazione emotiva” di fronte alla società statunitense e alle sue grandi città. Sono molti i testi nati nel quadro del dialogo con “il Paese di Dio”: oltre alle notissime conferenze americane e ad alcuni interventi non sistematici, Calvino ha scritto una serie di diari e dei testi ibridi che sarebbero confluiti in Un ottimista in America, il memoriale-reportage ritirato in fase di bozze. L’intervento ricostruisce i primi dialoghi con l’America e si sofferma su un episodio meno noto della bibliografia calviniana: il commento parlato al documentario America paese di Dio (Luigi Vanzi 1966), un testo che prende le mosse dall’opera “disvoluta” e che si presenta come una descrizione di immagini per “quell’altro mondo che era il mondo”.
L’intervento ricostruisce i primi dialoghi con l’America e si sofferma su un episodio meno noto della bibliografia calviniana: il commento parlato al documentario America paese di Dio (Luigi Vanzi, 1966), un testo che prende le mosse dall’opera «disvoluta» e che si presenta come una descrizione di immagini per «quell’altro mondo che era il mondo».
Mi clítoris se ríe contigo
Authors: Santiago Ortiz Beatriz
Published: February 2025

Lo primero que quería contaros es que –me ha dicho mi amiga que lo diga– yo nací graciosa, nací así. Mi madre durante muchísimo tiempo, cuando venían las vecinas y las amigas, decía: “Ay, es que mi hija Chusa es tan guapa. Y mi hija Bea es tan graciosa”. Que no sé muy bien si nací graciosa o mi madre me hizo graciosa, en realidad, porque su mirada era muy importante para mí. El caso es que esa esa forma de ser la graciosa me ha salvado de muchas cosas. Me ha protegido muchísimo. Ha sido la risa de la protección frente a una infancia un poco dura. La dureza no nos la quita nadie. La vida está llena de cosas muy duras. A veces no, pero la historia de cómo mirarlas o cómo afrontarlas es un poco de lo que yo vengo a hablar esta tarde. Quiero reírme contigo y quiero buscar ese placer. Y quiero que sepas que tu placer nace donde nace la risa y donde nace la risa es en tu clítoris, amiga, y eso es lo que tienes que meterte en la cabeza.
Pasión de las Santas Vírgenes Ágape, Quionia e Irene
Authors: Rivera Garretas María -Milagros
Published: February 2025

Pasión de las Santas Vírgenes Ágape, Quionia e Irene, a las que bajo el silencio nocturno el gobernador Dulcidio furtivamente se acercó anhelando saciarse de sus abrazos; pero, poco antes de entrar, enloqueciendo, en vez de a las vírgenes se puso a besar abrazándolas las ollas y sartenes, hasta que su rostro y su vestimenta se tiñeron de un tizne horrible. Entonces cedió a su compañero Sisinio el poder de castigar a las vírgenes; este, burlado también de modos milagrosos, ordenó finalmente que Ágape y Quionia fueran quemadas juntas e Irene fuera taladrada con saetas.
Literacidad crítica y formación inicial del profesorado en educación infantil.
Authors: González Milea Arasy
Published: February 2025

Desarrollar prácticas desde una literacidad crítica en la etapa de Educación Infantil se presenta como un reto, considerando la complejidad de esta fase educativa. Sin embargo, el primer paso para lograrlo es formar a maestros y maestras capaces de leer el mundo de manera crítica. Esta investigación cualitativa tiene como objetivo conocer en profundidad los cambios en el profesorado de Educación Infantil en formación inicial, tras haber participado en un programa formativo de la asignatura Didáctica de las Ciencias Sociales para la Educación Infantil, fundamentado en las bases de la literacidad crítica. Los resultados muestran que, aunque existen dificultades para delimitar conceptualmente la literacidad crítica y su práctica, tras recibir formación específica en la mencionada asignatura, se observan numerosas experiencias de éxito que demuestran que es posible formar en y para una literacidad crítica, en procesos que se desarrollen de manera más distendida a lo largo del tiempo.
Una investigación sobre la imaginación histórica: diseño e implementación en educación primaria
Authors: Bel Juan Carlos
Published: February 2025

En este artículo presentamos una investigación doctoral desarrollada durante los últimos años sobre el concepto de imaginación histórica en el aprendizaje de la historia. Así, en este texto describimos la estructura de la tesis doctoral y, posteriormente, mostramos el diseño y algunos de los resultados de un estudio de caso incluido en la tesis. Mediante este estudio de caso analizamos cómo una maestra elabora e implementa una unidad didáctica dirigida a desarrollar la imaginación histórica del alumnado, por medio del estudio de diferentes migraciones producidas en España durante el siglo XX. De forma global, todo ello nos permite mostrar cómo hemos abordado un objeto de investigación como el concepto de imaginación histórica en el conjunto de la tesis y, al mismo tiempo, poner el foco sobre cómo se pueden implementar parte de estas ideas y constructos en las aulas de Educación Primaria.
Creatividad y Ciencias Naturales. Una experiencia educativa con maestros en formación
Authors: Pont-Niclos Isabel , Izquierdo-Sanchis Eva , Echegoyen-Sanz Yolanda , Martín-Ezpeleta Antonio
Published: February 2025

En este trabajo se presenta y analiza una experiencia educativa innovadora contextualizada en la formación científica de los futuros maestros, que tiene por objetivo facilitar la asimilación de contenidos científicos (sobre salud y el cuerpo humano) al tiempo que se canaliza la creatividad. En concreto, se diseñaron actividades creativas, tales como la escritura de letras de canciones, la creación de murales interactivos y la grabación de videoclips destinados a un público infantil, de tal manera que estos productos de trabajos de los estudiantes supusieran una transposición didáctica y la generación de recursos para el aula de Primaria. La realización de estas actividades se nutrió del uso de herramientas de inteligencia artificial (IA) y otros recursos digitales, lo cual enriqueció la factura final de todo ello y estimuló la motivación de los estudiantes. Los resultados obtenidos mediante el análisis sistemático de los productos creativos y diferentes instrumentos de evaluación (co-evaluación, auto-evaluación y observación directa) muestran un impacto positivo en la comprensión de los contenidos científicos y el desempeño creativo de los futuros maestros. El artículo concluye reflexionando sobre la pertinencia de integrar la creatividad y la IA en la enseñanza de las Ciencias y la formación del profesorado, así como la idoneidad de conjugar todo ello en procesos de transposición didáctica que impulsen el diseño de materiales didácticos originales y específicos.
Wikireflexió: un espai d’aprenentatge virtual per a la reflexió i comprensió de les fonts teòriques
Authors: Sangrà Toni
Published: February 2025

Les potencialitats educatives i acadèmiques que permet l’eina del Wiki a l’ensenyament universitari són múltiples. L’eina del Wiki consisteix en una pàgina virtual per a l’escriptura col·laborativa, on els estudiants poden anar afegint i canviant els continguts de la pàgina. D’acord amb les seves característiques, conflueixen elements educatius com la interacció entre estudiants i docents, aprofundir en els continguts de les matèries des del diàleg, potenciar la reflexivitat raonada, afavorir l’expressió d’idees pròpies, entre d’altres possibilitats. Per fer-ho, hem dut a terme un espai d’aprenentatge anomenat Wikireflexió, que desenvolupem en el marc d’una assignatura del Grau de Treball Social a la Universitat de Barcelona. Aquesta iniciativa compta amb el reconeixement com a innovació docent del Vicerectorat de Política Docent i del Programa de Recerca, Innovació i Millora de la Docència i l’Aprenentatge (RIMDA) de la Universitat de Barcelona.
En aquest article explorem aquestes potencialitats que permeten millorar la reflexió i la comprensió de lectures bibliogràfiques a través d’aquesta eina virtual. Reflexionem sobre les bases pedagògiques que sostenen aquest espai d’aprenentatge en el context de l’assignatura. A continuació, situem l’activitat del Wiki en el marc de la nostra docència, expliquem el seu desenvolupament i organització i finalment mostrem els resultats que s’estan donant amb l’ús del Wiki.
The London Encounter in “Daisy Miller”: James and the Henley Circle
Authors: Yun Misun
Published: February 2025

Abstract: This article examines how the critics of London: A Conservative Weekly Journal , especially its editor W. E. Henley, influenced James’s revisions of “Daisy Miller,” the implications of which are marked by the omission of the subtitle “a Study” in the New York Edition. Despite their pioneering attention to James’s artistry, London problematized his analytical “impartiality” as a lack of “individuality”—while implying that individuality is a masculine, non-American quality that can animate fiction as a work of art. Caught in this double bind, James was motivated to refine his vision of fiction into an object-oriented, non-dissecting study of character.
Henry James Framed: An Addendum
Authors: Anesko Michael
Published: February 2025

Abstract: Not long after Henry James Framed: Material Representations of the Master was published (2022), a previously unknown charcoal drawing of Henry James came up for auction. This early sketch of James was done by one of his Newport friends, Helena de Kay (later married to Richard Watson Gilder), probably in the Spring of 1872. As such, it would be the second known representation of James, done ten years after his first portrait was taken by John La Farge.
Real-time multi-depth holographic display using complex-valued neural network
Authors: Zhang Yuanzhe , Cheng Dewen , Wang Yesheng , Wang Yongdong , Shan Yuefan , Yang Tong , Wang Yongtian
Published: February 2025

Computer-generated holography (CGH) has made significant advancements and is considered a leading approach for near-eye 3D displays. Recent learning-based CGH methods address the time-quality trade-off of traditional approaches but often face challenges related to efficiency and computational demands, especially with real-valued networks in multi-depth settings. To overcome these issues, this study proposes a residual block-based complex-valued convolutional neural network (ResC-CNN) structure, integrated into a symmetric dual-network framework driven by a diffraction model, for real-time generation of multi-depth holographic displays. This approach enhances the network's ability to handle complex domain calculations in CGH, making the learning process more efficient. A layered depth image (LDI) dataset is also incorporated to improve scene information prediction accuracy. Numerical and optical experiment results indicate that our proposed framework significantly increases the real-time generation frame rate of holograms and enhances the fidelity of displayed details, offering a practical solution for high-quality, real-time multi-depth holographic displays in applications such as augmented reality.
Laser spectroscopy applied in radiocarbon dating with the bomb peak
Authors: Ling Qiang , Zhou Yan , Chen Daru , Varricchio Luca , Detti Amelia , Bartalini Saverio , Guan Zuguang
Published: February 2025

Bomb-peak dating plays a crucial role in forensic applications. By comparing the radiocarbon concentrations of samples containing biological carbon with the bomb-peak curve, their ages can be accurately determined. Accelerator mass spectroscopy (AMS) is currently the most advanced technique for radiocarbon analysis; however, it is hindered by high costs, complex construction, maintenance requirements, and labor-intensive sample preparation. In contrast,
S
aturated absorption
CA
vity
R
ing-down (SCAR) spectroscopy has merged as an innovative, cost-effective, and efficient alternative for radiocarbon analysis. This technique has already demonstrated its competitiveness in biofraction analysis. In this study, we report, for the first time, the application of SCAR spectroscopy in bomb-peak dating. Unlike AMS, SCAR spectroscopy directly measures the concentration of radiocarbon by analyzing the absorption spectrum of 14CO2 gas, eliminating the need for complex graphitization during sample preparation. To evaluate the feasibility of this technique in dating applications, we analyzed various types of samples, including wine, paper, and wood. The radiocarbon ages obtained using SCAR spectroscopy showed reasonable consistency with the age information of these samples, demonstrating its potential as a reliable tool for bomb-peak dating.
Giant structurally modulated intrinsic chirality of quasi-bound states in continuum
Authors: Zhao Wen Kui , Wang Sheng Yi , Jing Yu Hang , Ge Hua , Wang Qiu , Zeng Yong Quan , Jia Bo Wen , Xu Ning
Published: February 2025

Structurally modulated intrinsic chirality is a structural transformation phenomenon in photoresponsive molecules that is commonly utilized in biosensing and chemical analysis. In this study, we proposed an approach to achieve giant intrinsic chirality in a quasi-bound state in the continuum (Q-BICs)-slanted tetramer metasurface, where high Q factors and circular dichroism (CD) coexist. Empowered by the simultaneous resonance between toroidal dipole (TD) and electric quadrupole (EQ) modes, the intrinsic circular dichroism can be effectively tuned via variations in the slant angles of the metasurface. Our work not only addresses the lack of strong chiral materials in nature but also opens up new possibilities in chiroptical sensing, chemical analysis, and biotechnology.
Ultrafast and wide-spectral single-pixel tracking via composite spinning patterns
Authors: Tang Xi , Chen Zhendong , Chen Feifei , Liu Chengmin , Pan Jiayi , Zhang Zibang , Wu Zhoujie , Zhang Qican
Published: February 2025

Target detection and tracking based on single-pixel detectors enable high-speed and long-duration monitoring of fast-moving targets, showing great potential in various applications. However, traditional coding strategies based on digital micromirror devices (DMD) are significantly limited in refreshing speed and spectral response range, hindering their widespread use. Here, we propose an ultrafast and wide-spectral single-pixel tracking approach, which utilizes composite grating patterns encoded onto a spinning mask. By leveraging the continuous properties of coded phase and the wide-spectral transmission of photomasks, we experimentally demonstrate that this method can achieve single-pixel tracking at a speed of 400 kHz, covering a broad spectral range from ultraviolet to near infrared. We believe this cost-effective approach will promote the practical application of the single-pixel tracking technology in fields such as cytology, smart transportation, and others.
Co-existing topological and Volkov-Pankratov plasmonic edge states in magnetized graphene
Authors: Mukherjee Samyobrata , Savchuk Viktoriia , Allen Jeffery W. , Allen Monica S. , Shvets Gennady
Published: February 2025

Graphene placed in a perpendicular magnetic field supports optical modes known as magnetoplasmons which are transversally confined to the graphene layer. Unlike ordinary graphene plasmons, these magnetoplasmonic surface waves are characterized by a band gap corresponding to the cyclotron frequency. In addition, these magnetoplasmon bands are topological, characterized by a non-zero Chern number. This leads to the existence of topologically protected edge states at domain edges where the Chern number changes. Since the Chern number is dependent on the direction of the magnetic field, edge states exist at domain edges across which the magnetic field flips direction. Physically, the magnetic field can only flip direction at gradual domain edges with finite width creating topological heterojunctions. These topological heterojunctions support extra edge states known as Volkov-Pankratov edge states which can enter the band gap and support propagation in both directions. The number of Volkov-Pankratov states at a heterojunction varies as a function of the width of the gradual domain edge.
Randomized-illumination mixed-state single-shot diffractive imaging
Authors: Haham Gil Ilan , Cohen Oren
Published: February 2025

We propose a single-shot diffractive imaging scheme, relying on illuminating an object with several mutually in-coherent modulating probes. The resulting multiplexed diffraction pattern is recorded and used to reconstruct the object. Compared with standard CDI, our method is robust to dynamic range limitations and noise, and the reconstruction process does not stagnate. Compared to other coherent modulating schemes, it enables better single-shot reconstruction and requires less stringent assumptions. We demonstrate the method experimentally in the visible spectral range.
Gender beliefs and norms underlying intimate partner violence stigma among women living in Botswana: Results of an exploratory factor analysis
Authors: Ho-Foster Ari , Machisa Mercilene Tanyaradzwa , Moalusi Lorato Ruth , Christofides Nicola
Published: February 2025

Gender inequitable beliefs, blaming attitudes, externalised and internalised stigma are commonly recognised barriers for intimate partner violence (IPV) survivors seeking help. However, the measurement of IPV stigma, its associations with inequitable gender beliefs and impacts on survivor disclosure, help-seeking behaviours, and mental health outcomes remain understudied. We explored women’s agreement with statements about gendered power dynamics and violence in intimate heterosexual relationships, before identifying and psychometrically testing scales derived for measuring community norms and beliefs underlying stigma to IPV. We used data from a nationally representative sample of 596 women living in Botswana. Exploratory factor analysis (EFA) occurred with responses of IPV survivors, and involved items from the Community Ideas about Gender Relations, Community Ideas about Rape, and Gender Equitable Women Scales. For each EFA identified scale, we estimated reliability (McDonald’s omega (ω)) and correlation with psychosocial outcomes related to IPV stigma. Among IPV survivors, we also considered whether survivors had disclosed their experience of abuse to others prior to the interview. Some 40.9% (n = 244) of women have experienced physical and/or sexual IPV at least once in their lives. Among them, an EFA of 31 gender beliefs and norms identified three latent variables: community norms about male dominance over female partners (C-MDP) (11 items; ω = 0.86); respondent beliefs about male dominance over female partners (I-MDP) (12 items; ω = 0.83); and survivor blaming attitudes (SBA) for the IPV they experienced (8-items; ω = 0.83). Some 15% of survivors had attempted suicide in the past, 8% had disclosed having suicidal thoughts, 49% were considered at risk for depression, and 18% at risk for post-traumatic stress disorder. Survivors who more strongly endorsed C-MDP appeared more likely to have attempted suicide (p = 0.04), and less likely to have disclosed their IPV experience prior to the study (p = 0.002). Survivors who more strongly endorsed SBA appeared more likely to have had suicidal thoughts (p = 0.02) and greater post-traumatic stress symptoms (p = 0.06). C-MDP, I-MDP and SBA appear related to psychosocial and disclosure outcomes. Gendered social norms may play an important role in understanding how survivors experience IPV stigma. We recommend further research into culture-informed practices that act to socialise such norms.
Host plants selection of Centranthera grandiflora Benth. and nontargeted metabolomics analysis of its parasitic and non-parasitic samples
Authors: Jin Song , Li Yuchuan , Ni Jun , Xie Haili , Lei Falin , Liu He
Published: February 2025

According to the previous investigation and research of our group, it was found that Centranthera grandiflora Benth. (C. grandiflora for short) might be a root hemiparasitic plant. The experiments of mixed sowing of C. grandiflora and 9 companion plants that might be hosts were conducted, and the growth, biological yield and other indexes were observed. The results showed that Cyperus iria L. was the best host for C. grandiflora, and when they were mixed sowed, C. grandiflora had a vigorous growth above ground and the haustoria connected obviously below ground, while C. grandiflora could achieve blossoming and fruiting in the same year. Next, nontargeted metabonomics analysis methods were utilized to clarify the differences in metabolites between parasitized and non-parasitized C. grandiflora. A total of 82 metabolites with significant differences were screened. The main upregulated differential metabolites of non-parasitized plants were for plant growth, while that of parasitized plants were functional compounds such as EPA. Out of 82 differential metabolites, 32 were annotated into 37 KEGG pathways. Analysis of the 37 pathways in combination with the differential metabolites showed that in addition to being involved in the synthesis pathway of iridoid terpenes, the up-regulated metabolites of parasitized plants were involved in the synthesis pathways of several functional components, while that of non-parasitic plants were involved in the subsequent catabolism of monoterpenoid compounds, as well as the metabolic pathways of nutrients synthesis and catabolism, energy generation, and phytohormone production required for plant growth.
Examining attitudes about the virtual workplace: Associations between zoom fatigue, impression management, and virtual meeting adoption intent
Authors: Lim Chaeyun , Ratan Rabindra , Foxman Maxwell , Beyea David , Jeong David , Leith Alex P.
Published: February 2025

Impression management is a crucial tactic within the workplace milieu. This study establishes a connection between impression management and the negative self-evaluation stemming from heightened self-monitoring during virtual meetings (VM), which manifests in the form of Zoom (VM) fatigue. We conducted a cross-sectional survey, by recruiting 2,448 U.S.-based workers. Our survey results revealed that facial appearance dissatisfaction is associated with VM fatigue, resulting in lower intention to adopt VM technologies due to decreased perceived usefulness of VM technologies. Furthermore, building upon the Uses and Gratification (UG) perspective and the assumptions of the Social Information Processing (SIP) theory and the Hyperpersonal Model, our findings illuminate that VM fatigue prompts the use of impression management behaviors by using VM features closely linked to dissatisfaction with one’s facial appearance. The results suggest that utilization of impression management features in VMs is driven by needs related to facial appearance concerns, which is associated with impression management. This study extends the concept of impression management to VM environments in the workplace, underscoring the importance of addressing workers’ needs and well-being to foster worker-friendly VM communication environments and promote VM acceptance. This study identifies external factors within the Technology Acceptance Model by integrating the UG perspective, the SIP theory, and the Hyperpersonal Model to understand the mechanisms underlying VM fatigue and adoption in the emerging virtual workplace.
Coastal environmental changes in Ninh Thuan Province, South-Central Vietnam
Authors: Kozhikkodan Veettil Bijeesh , Acharki Siham , Puri Vikram , Teck Vanna
Published: February 2025

Vietnam’s coastal regions are highly vulnerable to natural hazards and human-induced changes, posing significant challenges to their ecological and socio-economic systems. The country’s mangrove vegetation spans its entire coastline and has been depleted for decades in many regions. Notably, Vietnam’s proactive stance on climate change mitigation received significant recognition during the 26th Conference of the Parties (COP26) to the United Nations Framework Convention on Climate Change. This study investigated five critical coastal environmental features (shoreline dynamics, drought conditions, soil salinity trends, mangrove deforestation, and reforestation, as well as spatiotemporal variations in aquaculture and salt farming areas) using satellite data and geospatial analysis. Findings revealed a 58% decline in mangrove areas between 1989 and 2023, with a sharp decline between 1989 and 2001, followed by a gradual recovery. Furthermore, soil salinity along the Ninh Thuan coast indicated a continuous increase, except during the strong La Niña period in 2001. Additionally, aquaculture and salt marshes have expanded significantly, changing land use patterns. These findings highlight the urgent need for integrated coastal zone management to mitigate environmental degradation and enhance ecosystem resilience. Future studies should investigate the socio-economic implications of these changes and evaluate restoration strategies for sustainable coastal development.