bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 2 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Authors: Liu Lucy , Nam Sangkil , Tian Yan , Yang Fan , Wu Jun , Wang Yan , Scuto Anna , Polychronopoulos Panos , Magiatis Prokopios , Skaltsounis Leandros , Jove Richard
Published: April 2023

Supplementary Figure 2 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Supplementary Figure 3 from Densely Granulated Murine NK Cells Eradicate Large Solid Tumors
Authors: Liu Rebecca B. , Engels Boris , Arina Ainhoa , Schreiber Karin , Hyjek Elizabeth , Schietinger Andrea , Binder David C. , Butz Eric , Krausz Thomas , Rowley Donald A. , Jabri Bana , Schreiber Hans
Published: April 2023

PDF file - 323K
Supplementary Figure 1 from Oxidation-Mediated DNA Cross-Linking Contributes to the Toxicity of 6-Thioguanine in Human Cells
Authors: Brem Reto , Karran Peter
Published: April 2023

PDF file, 90K, Xanthine oxidase levels in cell lines.
Supplementary Video 1 from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

MOV file - 2.5MB, Video for the mice receiving vehicle (day 80 after tumor cell injection via tail vein)
Supplementary Methods from CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies
Authors: Chen Shuang , Dai Yun , Pei Xin-Yan , Myers Jennifer , Wang Li , Kramer Lora B. , Garnett Mandy , Schwartz Daniella M. , Su Florence , Simmons Gary L. , Richey Justin D. , Larsen Dustin G. , Dent Paul , Orlowski Robert Z. , Grant Steven
Published: April 2023

PDF file - 108K
Supplementary Figure Legend from Genetic Ablation of Cav1 Differentially Affects Melanoma Tumor Growth and Metastasis in Mice: Role of Cav1 in Shh Heterotypic Signaling and Transendothelial Migration
Authors: Capozza Franco , Trimmer Casey , Castello-Cros Remedios , Katiyar Sanjay , Whitaker-Menezes Diana , Follenzi Antonia , Crosariol Marco , Llaverias Gemma , Sotgia Federica , Pestell Richard G. , Lisanti Michael P.
Published: April 2023

PDF file - 72K
Supplementary Figure Legends 1-3 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells
Authors: Du Xiaoli , Qian Xiaolan , Papageorge Alex , Schetter Aaron J. , Vass William C. , Liu Xi , Braverman Richard , Robles Ana I. , Lowy Douglas R.
Published: April 2023

PDF file - 56K
Supplementary Figure 3 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells
Authors: Du Xiaoli , Qian Xiaolan , Papageorge Alex , Schetter Aaron J. , Vass William C. , Liu Xi , Braverman Richard , Robles Ana I. , Lowy Douglas R.
Published: April 2023

PDF file - 1MB, Expression of CAV1 or the combination of low CAV1 with low DLC1 do not affect the prognostic significance of lung cancer patients in Director's challenge cohort
Supplementary Methods from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 61K
Supplementary Figure 2 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 143K, Identification of the interaction partners for Xpf in DT40 cells.
Supplementary Figure 2 from SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma
Authors: Bareiss Petra M. , Paczulla Anna , Wang Hui , Schairer Rebekka , Wiehr Stefan , Kohlhofer Ursula , Rothfuss Oliver C. , Fischer Anna , Perner Sven , Staebler Annette , Wallwiener Diethelm , Fend Falko , Fehm Tanja , Pichler Bernd , Kanz Lothar , Quintanilla-Martinez Leticia , Schulze-Osthoff Klaus , Essmann Frank , Lengerke Claudia
Published: April 2023

PDF file, 127K, Treatment of OVCAR-3 cells with an alternative SOX2 shRNA construct.
Supplementary Figure S3 from Peroxiredoxin-2 Represses Melanoma Metastasis by Increasing E-Cadherin/β-Catenin Complexes in Adherens Junctions
Authors: Lee Doo Jae , Kang Dong Hoon , Choi Mina , Choi Yang Ji , Lee Joo Young , Park Joo Hyun , Park Yoon Jung , Lee Kyung Wha , Kang Sang Won
Published: April 2023

Supplementary Figure S3 -�PDF file 79K, Quality control of antibodies against adherens junctional proteins
Supplementary Figure 2 from A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
Authors: Zhou Bingsen , Su Leila , Hu Shuya , Hu Weidong , Yip M.L. Richard , Wu Jun , Gaur Shikha , Smith D. Lynne , Yuan Yate-Ching , Synold Timothy W. , Horne David , Yen Yun
Published: April 2023

PDF file - 44K, Supplemental figure 2: NMR validation of Pocket 5.
Figure S6 from Hbo1 Is a Cyclin E/CDK2 Substrate That Enriches Breast Cancer Stem-like Cells
Authors: Duong MyLinh T. , Akli Said , Macalou Sira , Biernacka Anna , Debeb Bisrat G. , Yi Min , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

Figure S6: Salinomycin treatment induces a shift from CD44hi/CD24lo population to CD44hi/CD24hi population in LMW-E-expressing tumors.
Supplementary Table 1 from Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A
Authors: Bascom Jamie L. , Radisky Derek C. , Koh Eileen , Fata Jimmie E. , Lo Alvin , Mori Hidetoshi , Roosta Neda , Hirai Yohei , Bissell Mina J.
Published: April 2023

PDF file, 48K, PCR primers used in study.
Supplementary Figure 1 from Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A
Authors: Bascom Jamie L. , Radisky Derek C. , Koh Eileen , Fata Jimmie E. , Lo Alvin , Mori Hidetoshi , Roosta Neda , Hirai Yohei , Bissell Mina J.
Published: April 2023

PDF file, 3359K, Effect of Epim on ductal length, terminal endbuds, and lobuloalveolar structure formation.
Supplementary Figure 1 from Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Authors: Huo Shuaidong , Ma Huili , Huang Keyang , Liu Juan , Wei Tuo , Jin Shubin , Zhang Jinchao , He Shengtai , Liang Xing-Jie
Published: April 2023

PDF file - 100K, Characterization of 15 nm Au@citrate nanoparticles
Supplementary Table 1 from Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures
Authors: Ju Xiaoming , Ertel Adam , Casimiro Mathew C. , Yu Zuoren , Meng Hui , McCue Peter A. , Walters Rhonda , Fortina Paolo , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

PDF file - 220KB, Analysis of gene copy number of isogenic prostate cancer cell lines.
Supplementary Figure 1 from ABL Regulation by AXL Promotes Cisplatin Resistance in Esophageal Cancer
Authors: Hong Jun , Peng DunFa , Chen Zheng , Sehdev Vikas , Belkhiri Abbes
Published: April 2023

PDF file - 696K, Real-time RT-PCR data
Supplementary Methods, Tables 1 - 6, Figures 1 - 5 from APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma
Authors: Leonard Brandon , Hart Steven N. , Burns Michael B. , Carpenter Michael A. , Temiz Nuri A. , Rathore Anurag , Vogel Rachel I. , Nikas Jason B. , Law Emily K. , Brown William L. , Li Ying , Zhang Yuji , Maurer Matthew J. , Oberg Ann L. , Cunningham Julie M. , Shridhar Viji , Bell Debra A. , April Craig , Bentley David , Bibikova Marina , Cheetham R. Keira , Fan Jian-Bing , Grocock Russell , Humphray Sean , Kingsbury Zoya , Peden John , Chien Jeremy , Swisher Elizabeth M. , Hartmann Lynn C. , Kalli Kimberly R. , Goode Ellen L. , Sicotte Hugues , Kaufmann Scott H. , Harris Reuben S.
Published: April 2023

PDF file - 481K, Table S1: Cell line information Table S2: Quantitative PCR primer and probe sequences. Table S3: Non-malignant tissues tested Table S4: Early stage serous ovarian tumors used in sequence analyses Table S5: Additional ovarian tumor specimens analyzed Table S6: Microarray analysis of APOBEC3 and select control gene probe sets in ovarian TCGA data Figure S1: Polynucleotide cytosine deaminase expression in ovarian cell lines. Figure S2: Endogenous DNA deaminase activity in APOBEC3B high and low cell lines. Figure S3: Endogenous APOBEC3B activity on alternate dinucleotide substrates. Figure S4: Polynucleotide cytosine deaminase expression in ovarian primary samples. Figure S5: Polynucleotide cytosine deaminase expression in ovarian TCGA samples by RNAseq.
Supplementary Figure Legend from Targeting Sonic Hedgehog-Associated Medulloblastoma through Inhibition of Aurora and Polo-like Kinases
Authors: Markant Shirley L. , Esparza Lourdes Adriana , Sun Jesse , Barton Kelly L. , McCoig Lisa M. , Grant Gerald A. , Crawford John R. , Levy Michael L. , Northcott Paul A. , Shih David , Remke Marc , Taylor Michael D. , Wechsler-Reya Robert J.
Published: April 2023

PDF file - 43K
Supplementary Methods from Gut Microbiota Protects against Gastrointestinal Tumorigenesis Caused by Epithelial Injury
Authors: Zhan Yu , Chen Po-Ju , Sadler William D. , Wang Fuyuan , Poe Sara , Núñez Gabriel , Eaton Kathryn A. , Chen Grace Y.
Published: April 2023

PDF file - 103K, Description of additional methods and procedures used in the study. Also includes primer sequences.
Supplementary Table 2 from Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas
Authors: Jin Genglin , Reitman Zachary J. , Duncan Christopher G. , Spasojevic Ivan , Gooden David M. , Rasheed B. Ahmed , Yang Rui , Lopez Giselle Y. , He Yiping , McLendon Roger E. , Bigner Darell D. , Yan Hai
Published: April 2023

PDF file-23KB, D-2HG in cell line lysate samples, as assessed by LC-MS/M
Supplementary Table 1 from Disruption of Wild-Type IDH1 Suppresses D-2-Hydroxyglutarate Production in IDH1-Mutated Gliomas
Authors: Jin Genglin , Reitman Zachary J. , Duncan Christopher G. , Spasojevic Ivan , Gooden David M. , Rasheed B. Ahmed , Yang Rui , Lopez Giselle Y. , He Yiping , McLendon Roger E. , Bigner Darell D. , Yan Hai
Published: April 2023

PDF file-22KB, D-2HG in primary human glioma tissue samples, as assessed by LC-MS/MS
Supplementary Figure Legend from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 114K
Supplementary Figure 7 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 1205K, Figure S7. Treatment of HER2 amplified cell lines with LJM716/ trastuzumab combinations is synergistic in a subset of cell lines.
Supplementary Figure 2 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 268K, Figure S2. LJM716 inhibits HER3 mediated PI3K signaling.
Supplementary Figure 3 from DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Authors: Cao Jianzhong , Song Yongmei , Bi Nan , Shen Jie , Liu Wenyang , Fan Jing , Sun Guogui , Tong Tong , He Jie , Shi Yuankai , Zhang Xun , Lu Ning , He Yinghua , Zhang Hongyu , Ma Kelong , Luo Xiaoying , Lv Lei , Deng Hui , Cheng Jing , Zhu Jingde , Wang Luhua , Zhan Qimin
Published: April 2023

PDF file - 78K, DNA methylation status of the miR-886 promoter in NCI-H69, NCI-H209 and NCI-H524 cell lines.
Supplementary Figure 2 from Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
Authors: Liu Yu-Peng , Liao Wen-Chi , Ger Luo-Ping , Chen Jiun-Chin , Hsu Tai-I , Lee Yu-Cheng , Chang Hong-Tai , Chen Yu-Chia , Jan Yi-Hua , Lee Kuen-Haur , Zeng Yu-Hao , Hsiao Michael , Lu Pei-Jung
Published: April 2023

PDF file, 70K, PI3K inibitor blocked serum-induced Akt phosphorylation.
Supplementary Figure 1 from Intestinal Bacteria Modify Lymphoma Incidence and Latency by Affecting Systemic Inflammatory State, Oxidative Stress, and Leukocyte Genotoxicity
Authors: Yamamoto Mitsuko L. , Maier Irene , Dang Angeline Tilly , Berry David , Liu Jared , Ruegger Paul M. , Yang Jiue-in , Soto Phillip A. , Presley Laura L. , Reliene Ramune , Westbrook Aya M. , Wei Bo , Loy Alexander , Chang Christopher , Braun Jonathan , Borneman James , Schiestl Robert H.
Published: April 2023

PDF file - 226K, Relative Abundance of Indicator Bacterial Phylotypes in Mice Fecal bacteria of age- and litter-matched SPF-N and SPF-S mice (n = 4-5 for each type) were subjected to an indicator analysis.
Supplementary Figure 4 from Characterization of Rearrangements Involving the ALK Gene Reveals a Novel Truncated Form Associated with Tumor Aggressiveness in Neuroblastoma
Authors: Cazes Alex , Louis-Brennetot Caroline , Mazot Pierre , Dingli Florent , Lombard Bérangère , Boeva Valentina , Daveau Romain , Cappo Julie , Combaret Valérie , Schleiermacher Gudrun , Jouannet Stéphanie , Ferrand Sandrine , Pierron Gaëlle , Barillot Emmanuel , Loew Damarys , Vigny Marc , Delattre Olivier , Janoueix-Lerosey Isabelle
Published: April 2023

PDF file - 144K, Insert size distributions of fragment lengths after capture and paired-end sequencing for the 10 samples studied
Supplementary Materials and Methods from FGFR1 Is Essential for Prostate Cancer Progression and Metastasis
Authors: Yang Feng , Zhang Yongyou , Ressler Steven J. , Ittmann Michael M. , Ayala Gustavo E. , Dang Truong D. , Wang Fen , Rowley David R.
Published: April 2023

PDF File - 82K, Supplemental data show FGFR1 knockout effects on prostate development, flow chart for mouse breeding, in situ hybridization controls, and TUNEL staining results.
Supplementary Materials and Methods from Novel Recombinant Human B7-H4 Antibodies Overcome Tumoral Immune Escape to Potentiate T-Cell Antitumor Responses
Authors: Dangaj Denarda , Lanitis Evripidis , Zhao Aizhi , Joshi Shree , Cheng Yi , Sandaltzopoulos Raphael , Ra Hyun-Jeong , Danet-Desnoyers Gwenn , Powell Daniel J. , Scholler Nathalie
Published: April 2023

Supplementary Materials and Methods - PDF file 113K, Additional experimental procedures including Western Blot, Flow Cytometry, and Xenograft models
Supplementary Figure 1 from RANKL Expression, Function, and Therapeutic Targeting in Multiple Myeloma and Chronic Lymphocytic Leukemia
Authors: Schmiedel Benjamin Joachim , Scheible Carolin Andrea , Nuebling Tina , Kopp Hans-Georg , Wirths Stefan , Azuma Miyuki , Schneider Pascal , Jung Gundram , Grosse-Hovest Ludger , Salih Helmut Rainer
Published: April 2023

PDF file - 184K, (A) The RANKL antibodies MIH23 and MIH24 specifically bind to RANKL. Binding of MIH23 and MIH24 to surface expressed RANKL was determined by FACS using RANKL transfectants (L-RANKL) and control cells (L cells). Shaded peaks, specific mAb (MIH23 and MIH24); open peaks, isotype controls (mouse IgM and mouse IgG2b, respectively). (B) MIH23 and MIH24 block RANK-RANKL interaction. RANKL transfectants and the parental controls were stained with RANK-Ig (shaded peaks) or human IgG1 (open peaks) followed by anti-human-PE and investigated by FACS. Dotted line: staining after preincubation with the indicated RANKL mAb; dashed line: after preincubation with mouse IgM and mouse IgG2b as respective isotype controls. (C) Sensitivity and specificity of the sandwich ELISA for detection of sRANKL. The indicated serial dilutions of rRANKL in culture medium were analyzed as described in the methods section. X represents 100ng/ml rGITRL as control. The dotted line represents the chosen detection limit of 0.05ng/ml. Means of triplicates with standard deviations are shown. (D, E) MM cell lines do not display RANKL protein on the surface despite expression of mRANKL mRNA. The indicated MM cell lines were analyzed for RANKL surface and mRNA expression by FACS (D) and RT-PCR (E) as described in the methods section. Results obtained with RANKL transfectants and parental cells are shown as controls.
Supplementary Figure S3 from Novel Recombinant Human B7-H4 Antibodies Overcome Tumoral Immune Escape to Potentiate T-Cell Antitumor Responses
Authors: Dangaj Denarda , Lanitis Evripidis , Zhao Aizhi , Joshi Shree , Cheng Yi , Sandaltzopoulos Raphael , Ra Hyun-Jeong , Danet-Desnoyers Gwenn , Powell Daniel J. , Scholler Nathalie
Published: April 2023

Supplementary Figure S3 - PDF file 345K, Strategies for isolation of anti-B7-H4 scFvs from a new yeast-display scFv library derived from ovarian cancer patients
Supplementary Figure 4 from β-Catenin Signaling Is a Critical Event in ErbB2-Mediated Mammary Tumor Progression
Authors: Schade Babette , Lesurf Robert , Sanguin-Gendreau Virginie , Bui Tung , Deblois Geneviève , O'Toole Sandra A. , Millar Ewan K.A. , Zardawi Sara J. , Lopez-Knowles Elena , Sutherland Robert L. , Giguère Vincent , Kahn Michael , Hallett Michael , Muller William J.
Published: April 2023

PDF file - 135K, Loss of endogenous β-catenin in ErbB2KI-derived mammary tumor cells (TM15 c10-2 and c7-2) impairs their invasion capacity in vitro.
Supplementary Figures 1 - 5 from Supramolecular Nanoparticles That Target Phosphoinositide-3-Kinase Overcome Insulin Resistance and Exert Pronounced Antitumor Efficacy
Authors: Kulkarni Ashish A. , Roy Bhaskar , Rao Poornima S. , Wyant Gregory A. , Mahmoud Ayaat , Ramachandran Madhumitha , Sengupta Poulomi , Goldman Aaron , Kotamraju Venkata Ramana , Basu Sudipta , Mashelkar Raghunath A. , Ruoslahti Erkki , Dinulescu Daniela M. , Sengupta Shiladitya
Published: April 2023

PDF file - 314K, Characterization of PI103-cholesterol conjugated (S1); Characterization of PI828-cholesterol conjugated (S2); Characterization of PI103-cholesterol conjugate (S3); Synthesis and characterization of PI103-encapsulated nanoparticles (S4); In vivo efficacy of PI828-SNPs in 4T1 breast cancer BALB/c mice bearing 8 day old subcutaneous tumors (S5).
Supplementary Figure Legends from Mathematical Modeling of Tumor Cell Proliferation Kinetics and Label Retention in a Mouse Model of Lung Cancer
Authors: Zheng Yanyan , Moore Helen , Piryatinska Alexandra , Solis Trinidad , Sweet-Cordero E. Alejandro
Published: April 2023

PDF File - 49K, Percentage of BrdU+ cells for each sample, colored by mouse.
Supplementary Figure 2 from Mathematical Modeling of Tumor Cell Proliferation Kinetics and Label Retention in a Mouse Model of Lung Cancer
Authors: Zheng Yanyan , Moore Helen , Piryatinska Alexandra , Solis Trinidad , Sweet-Cordero E. Alejandro
Published: April 2023

PDF File - 18K, Percentage of BrdU+ cells for each sample, colored by mouse.
Supplementary Methods from Kinetic Modeling–Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network
Authors: Vera Julio , Schmitz Ulf , Lai Xin , Engelmann David , Khan Faiz M. , Wolkenhauer Olaf , Pützer Brigitte M.
Published: April 2023

PDF file - 267K, Includes regulatory map construction data, core regulatory module, tumor cell population, model calibration, model simulations, and appropriate references
Supplementary Table S1 from A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
Authors: Lau Ted , Chan Emily , Callow Marinella , Waaler Jo , Boggs Jason , Blake Robert A. , Magnuson Steven , Sambrone Amy , Schutten Melissa , Firestein Ron , Machon Ondrej , Korinek Vladimir , Choo Edna , Diaz Dolores , Merchant Mark , Polakis Paul , Holsworth Daniel D. , Krauss Stefan , Costa Mike
Published: April 2023

Supplementary Table S1 - PDF file 18K, Tankyrase inhibitor potency and selectivity
Supplementary Figure S4 from A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
Authors: Lau Ted , Chan Emily , Callow Marinella , Waaler Jo , Boggs Jason , Blake Robert A. , Magnuson Steven , Sambrone Amy , Schutten Melissa , Firestein Ron , Machon Ondrej , Korinek Vladimir , Choo Edna , Diaz Dolores , Merchant Mark , Polakis Paul , Holsworth Daniel D. , Krauss Stefan , Costa Mike
Published: April 2023

Supplementary Fig. S4 - PDF file 724K, G007-LK effects in mice at toxic doses.(A) Higher magnification view, compared to Fig. 6C, of the ileum (H&E stained section) showing villous blunting (between arrow and arrowhead), fusion, and neutrophilic inflammation within the lamina propria and lumen (above arrowhead) in a mouse treated with 60 mg/kg G007-LK IP QD for 10 days. (B) Systemic inflammatory and protein-losing enteropathy responses in blood samples from mice treated with 60 mg/kg or 100 mg/kg G007-LK IP QD for 10 or 9 days, respectively, as indicated. The upper graph shows absolute neutrophil counts (Neut) and percentage of immature neutrophils (Bands), and the lower graph depicts serum albumin levels
Supplementary Video 3 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Authors: Pérez de Castro Ignacio , Aguirre-Portolés Cristina , Fernández-Miranda Gonzalo , Cañamero Marta , Cowley Dale O. , Van Dyke Terry , Malumbres Marcos
Published: April 2023

AVI file - 500KB, Time-lapse live imaging of H2B-EGFP-expressing, control MEFs undergoing normal cell cycle.
Supplementary Figure 5 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
Authors: Pérez de Castro Ignacio , Aguirre-Portolés Cristina , Fernández-Miranda Gonzalo , Cañamero Marta , Cowley Dale O. , Van Dyke Terry , Malumbres Marcos
Published: April 2023

PDF file - 133KB, Characterization of Aurora-A null skin.
Supplementary Video 1 from Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
Authors: Costea Daniela Elena , Hills Allison , Osman Amani H. , Thurlow Johanna , Kalna Gabriela , Huang Xiaohong , Pena Murillo Claudia , Parajuli Himalaya , Suliman Salwa , Kulasekara Keerthi K. , Johannessen Anne Chr. , Partridge Max
Published: April 2023

MP4 file - 752K, 1. Time-lapse microscopy of CAF1 plated onto collagen I showing the diversity of CAF movement, with a predominance of motile cells with longer tracks. Images were captured every 10 mins and analysed using IMARIS software. The centre of each CAF is marked by a grey square. Migration was visualized by a track that changes colour in time as shown by the scale lower right corner. Examples of highly motile CAF are shown in the left quadrants and less motile CAF at the junction of the upper and lower left quadrants. Quantification of the migration is shown in supplementary Table ST1.
Supplementary Figure 2 from PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
Authors: Badoual Cécile , Hans Stéphane , Merillon Nathalie , Van Ryswick Cordélia , Ravel Patrice , Benhamouda Nadine , Levionnois Emeline , Nizard Mevyn , Si-Mohamed Ali , Besnier Nicolas , Gey Alain , Rotem-Yehudar Rinat , Pere Hélène , Tran Thi , Guerin Coralie L. , Chauvat Anne , Dransart Estelle , Alanio Cécile , Albert Sebastien , Barry Beatrix , Sandoval Federico , Quintin-Colonna Françoise , Bruneval Patrick , Fridman Wolf H. , Lemoine Francois M. , Oudard Stephane , Johannes Ludger , Olive Daniel , Brasnu Daniel , Tartour Eric
Published: April 2023

PDF file - 3.4MB, Relationship between PDL-1 expression and survival
Supplementary Figure 1 from PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
Authors: Badoual Cécile , Hans Stéphane , Merillon Nathalie , Van Ryswick Cordélia , Ravel Patrice , Benhamouda Nadine , Levionnois Emeline , Nizard Mevyn , Si-Mohamed Ali , Besnier Nicolas , Gey Alain , Rotem-Yehudar Rinat , Pere Hélène , Tran Thi , Guerin Coralie L. , Chauvat Anne , Dransart Estelle , Alanio Cécile , Albert Sebastien , Barry Beatrix , Sandoval Federico , Quintin-Colonna Françoise , Bruneval Patrick , Fridman Wolf H. , Lemoine Francois M. , Oudard Stephane , Johannes Ludger , Olive Daniel , Brasnu Daniel , Tartour Eric
Published: April 2023

PDF file - 2.6MB, Characterization of PD1+CD45+ cells
Supplementary Methods , Figure Legends 1-8, Tables 1-3 from EGFR/JIP-4/JNK2 Signaling Attenuates Cetuximab-Mediated Radiosensitization of Squamous Cell Carcinoma Cells
Authors: Eke Iris , Schneider Lydia , Förster Claudia , Zips Daniel , Kunz-Schughart Leoni A. , Cordes Nils
Published: April 2023

PDF file - 109K, Supplementary Table S1. Plating efficiencies of SCC cells differ between 2D and 3D cell culture conditions cell line-dependently. Supplementary Table S2. JIP-4, Grb2 and STE20-like kinase bind to EGFR in untreated FaDu 3D cell cultures as determined by immunoprecipitation and subsequent mass spectrometry. Supplementary Table S3. Knockdown of JIP-4 and JNK2 in combination with Cetuximab synergistically impact on radiation survival of SCC cells
Supplementary Figure Legend, Table 1 from Synergistic Induction of Adaptive Antitumor Immunity by Codelivery of Antigen with α-Galactosylceramide on Exosomes
Authors: Gehrmann Ulf , Hiltbrunner Stefanie , Georgoudaki Anna-Maria , Karlsson Mikael C. , Näslund Tanja I. , Gabrielsson Susanne
Published: April 2023

PDF file - 136K, List of antibodies used in this study.
Supplementary Methods from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 23K, Contains a detailed version of methods used for the internalization assays shown in Figure S5.
Supplementary Figure 3 from Synergistic Induction of Adaptive Antitumor Immunity by Codelivery of Antigen with α-Galactosylceramide on Exosomes
Authors: Gehrmann Ulf , Hiltbrunner Stefanie , Georgoudaki Anna-Maria , Karlsson Mikael C. , Näslund Tanja I. , Gabrielsson Susanne
Published: April 2023

PDF file - 22K, Increased proliferation of follicular helper T cells following exosome injection.
Supplementary Figure 4 from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 180K, The association between Trop-2 and β1 integrins occurs independently on β1 activation or adhesion to ECM ligands.
Supplementary Table 3 from Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas
Authors: Paugh Barbara S. , Zhu Xiaoyan , Qu Chunxu , Endersby Raelene , Diaz Alexander K. , Zhang Junyuan , Bax Dorine A. , Carvalho Diana , Reis Rui M. , Onar-Thomas Arzu , Broniscer Alberto , Wetmore Cynthia , Zhang Jinghui , Jones Chris , Ellison David W. , Baker Suzanne J.
Published: April 2023

XLS file, 10K, Histopathology of PDGFRa-driven tumors.
Supplementary Figure Legends from Bone Marrow–Derived CD11b+Jagged2+ Cells Promote Epithelial-to-Mesenchymal Transition and Metastasization in Colorectal Cancer
Authors: Caiado Francisco , Carvalho Tânia , Rosa Isadora , Remédio Leonor , Costa Ana , Matos João , Heissig Beate , Yagita Hideo , Hattori Koichi , da Silva João Pereira , Fidalgo Paulo , Pereira António Dias , Dias Sérgio
Published: April 2023

PDF file - 40K, Legend for Supplementary Figures S1 and S2
Supplementary Table 3 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

XLSX file - 337K, Excel sheet containing the list of compounds from Supplemental Figure 9.
Supplementary Figure 7 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 53K, 7A, Inhibitors of Akt could not block growth inhibition induced by E2 in MCF-7:5C cells. MCF-7:5C cells were treated with vehicle (0.1% EtOH), E2 (10-9 mol/L), LY294002 (10-6mol/L), and E2 (10-9 mol/L) plus LY294002 (10-6mol/L) respectively. Cells were harvested after 7 days treatment and total DNA was determined using a DNA fluorescence quantitation kit. 7B, Inhibitor of MAPK could not block growth inhibition induced by E2 in MCF-7:5C cells. MCF-7:5C cells were treated with vehicle (0.1% EtOH), E2 (10-9 mol/L), U0126 (5x10-6 mol/L), and E2 (10-9 mol/L) plus U0126 (5x10-6 mol/L) respectively. Cells were harvested after 7 days treatment and total DNA was determined using a DNA fluorescence quantitation kit. All data shown were representative of at least three separate experiments with similar results.
Supplementary Figure 6 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 82K, 6A, The c-Src inhibitor blocked tumor necrosis factor (TNF) super family genes induced by E2. MCF-7:5C cells were treated with vehicle (0.1% DMSO), E2 (10-9 mol/L), 4-OHT (10-6 mol/L), E2 (10-9 mol/L) plus 4-OHT (10-6 mol/L), PP2 (5x10-6 mol/L), E2 (10-9 mol/L) plus PP2 (5x10-6 mol/L) respectively for 72 hours. Cells were harvested in TRIzol. LTA (TNF super family member 1) gene was detected by real-time PCR. P<0.001, ** compared with control. 6B, LTB (TNF super family member 3) gene was detected by real-time PCR. P<0.001, ** compared with control. 6C, TNFα activated apoptotic pathways in MCF-7:5C cells. MCF-7:5C cells were treated with vehicle (H2O) and TNFα (5ng/mL) for 24 hours. Cell lysates were harvested. Pro-apoptotic pathways PARP and Caspase-9 were examined by immunoblotting with primary antibodies. Immunoblotting for beta-actin was detected for loading control. 6D, TNFα inhibited MCF-7:5C cell growth. MCF-7:5C cells were treated with vehicle (H2O) and TNFα (5ng/mL) for 7 days. Cells were harvested and total DNA was determined using a DNA fluorescence quantitation kit. P<0.001, ** compared with control. All the data shown were representative of at least three separate experiments with similar results.
Supplementary Figure 4 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 76K, The c-Src inhibitor blocked apoptosis-related genes induced by E2. MCF-7:5C cells were treated with vehicle (0.1% DMSO), E2 (10-9 mol/L), 4-OHT (10-6 mol/L), E2 (10-9 mol/L) plus 4-OHT(10-6 mol/L), PP2 (5x10-6 mol/L), E2 (10-9 mol/L) plus PP2 (5x10-6 mol/L) respectively for 72 hours. Cells were harvested in TRIzol for real-time PCR. 4A, PPP1R15A (GADD34) gene. 4B, BCL2L11 (Bim) gene. 4C, NUAK2 gene. 4D, PMAIP1 (Noxa) gene. P<0.001, ** compared with control. All the data shown were representative of at least three separate experiments with similar results.
Supplementary Figure Legend from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

PDF file - 125K
Supplementary Figure 1 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 77K, 1A, The c-Src inhibitor blocked E2 activated non-genomic pathway. MCF-7:5C cells were treated with vehicle (0.1% DMSO), E2 (10-9 mol/L), PP2 (5x10-6 mol/L), E2 (10-9 mol/L) plus PP2 (5x10-6 mol/L) respectively for 10 minutes and the cell lysates were harvested. Phosphorylated MAPK and c-Src were examined by immunoblotting with primary antibodies. Immunoblotting for total MAPK and c-Src were used for loading controls. 1B, E2 rapidly activated MAPK and c-Src. MCF-7:5C cells were treated with vehicle (0.1% EtOH) and E2 (10-9 mol/L) for different time points as indicated and the cell lysates were harvested. Phosphorylated MAPK and c-Src were examined by immunoblotting with primary antibodies. Immunoblotting for total MAPK and c-Src were used for loading controls. 1C, E2 stimulated c-Src after 24 hours treatment. MCF-7:5C cells were treated with vehicle (0.1% EtOH) and E2 (10-9 mol/L) for different time points as indicated and the cell lysates were harvested. Phosphorylated c-Src was examined by immunoblotting with primary antibody. Immunoblotting for total c-Src was used for loading control. 1D, Quantification of Annexin V binding assay. MCF-7:5C cells were treated with vehicle (0.1% DMSO), E2 (10-9 mol/L), 4-OHT (10-6 mol/L), E2 (10-9 mol/L) plus 4-OHT (10-6 mol/L), PP2 (5x10-6 mol/L), E2 (10-9 mol/L) plus PP2 (5x10-6 mol/L) respectively for 72 hours and the cells were harvested for Annexin V binding assay through flow cytometry. The percentage of Annexin V binding was compared with control. P<0.05, * compared with control. All the data shown were representative of at least three separate experiments with similar results.
Supplementary Figure 10 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

PDF file - 880K, Volcano plots for 28 FDA approved cancer drugs of interest.
Supplementary Table 3 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: April 2023

PDF file - 64K, Gene array data summary.
Supplementary Table 2 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: April 2023

PDF file - 65K, Gene array data summary.
Supplementary Figure 2 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: April 2023

PDF file - 69K, iNOS induced expressions of Wnt signaling pathway related-genes. A, A pair of SW480 cell lines was generated that stably overexpressed hiNOS (SW480-iNOS), compared with its control cell line (SW480-GFP), which were used for the SuperArray analysis. Expressions of Wnt signaling pathway related-genes (114 genes) in SW480-iNOS compared with SW480-GFP is shown. Cells were incubated for 24 hours and total RNA was isolated for the SuperArray analysis. B, In SuperArray analysis, the red + spots indicate a gene expression ratio >1.5 of SW480-iNOS / SW480-GFP cells, whereas the green + sign indicates a ratio < 1.5 of SW480-iNOS / SW480-GFP cells.
Supplementary Figure 1 from Nitric Oxide Production Upregulates Wnt/β-Catenin Signaling by Inhibiting Dickkopf-1
Authors: Du Qiang , Zhang Xinglu , Liu Quan , Zhang Xianghong , Bartels Christian E. , Geller David A.
Published: April 2023

PDF file - 100K, Expressions of iNOS, DKK1 and Beta-catenin in human cancer tissues. A, HE staining of human tissue specimen was obtained from 4 patients with colon cancer. Scale bars, 50 microM. B, P21 CIP1/WAF1 gene expression in colon cancer tissues was compared with normal adjacent tissues determined by qRT-PCR. C, Primary human breast cancer specimens were stained with the indicated antibodies specific to iNOS, DKK1 and Beta-catenin by immunofluorescent analysis. Scale bars, 20 microM.
Supplementary Tables 1 - 19 from A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
Authors: Sheltzer Jason M.
Published: April 2023

XLSX file - 143K, Supplemental Table S1. GO terms enriched among genes correlated or anti-correlated with aneuploidy in MEFs. Supplemental Table S2. GO terms enriched among genes correlated or anti-correlated with karyotypic heterogeneity in cancer cell lines. Supplemental Table S3. GO terms enriched among genes correlated or anti-correlated with aneuploidy in MEFs, as determined by GSEA Supplemental Table S4. GO terms enriched among genes correlated or anti-correlated with karyotype heterogeneity in cancer cell lines, as determined by GSEA Supplemental Table S5. GO terms enriched among genes similarly affected by cancer and aneuploidy in primary cells. Supplemental Table S6. GO terms enriched among genes differentially affected by cancer and aneuploidy in primary cells. Supplemental Table S7. Enrichment of transcription factor motifs in the promoters of CIN-correlated genes. Table S8. GO terms enriched among genes correlated or anti-correlated with doubling time in cancer cell lines. Table S9. GO terms enriched among genes that are more strongly correlated or anti-correlated with CIN than with doubling time. Table S10. Metabolic pathways enriched among metabolites that are correlated or anti-correlated with karyotypic heterogeneity in cancer cell lines. Table S11. Metabolic pathways enriched among metabolites that are correlated or anti-correlated with doubling time in cancer cell lines. Supplemental Table S12. GO terms enriched among genes upregulated or downregulated by chromosome transfer into HCT-116 cells. Supplemental Table S13. Enrichment of transcription factor motifs in the promoters of genes upregulated or downregulated by chromosome transfer. Supplemental Table S14. The PCNA25 gene signature. Supplemental Table S15. The TRI70 gene signature. Table S16. The HET70 gene signature. Table S17. Stratification of patient risk by proliferation and aneuploidy-related gene signatures in published clinical cohorts. Table S18. Stratification of patient risk by the HET5 gene signature (training set). Table S19. Stratification of patient risk by the HET5 gene signature (test set).
Supplementary Table 1 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling
Authors: Schackmann Ron C.J. , Klarenbeek Sjoerd , Vlug Eva J. , Stelloo Suzan , van Amersfoort Miranda , Tenhagen Milou , Braumuller Tanya M. , Vermeulen Jeroen F. , van der Groep Petra , Peeters Ton , van der Wall Elsken , van Diest Paul J. , Jonkers Jos , Derksen Patrick W.B.
Published: April 2023

PDF - 56K, Clinicopathological characteristics of 298 invasive ductal breast cancers studied for the expression of p120.
Supplementary Methods from Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses
Authors: Mitchem Jonathan B. , Brennan Donal J. , Knolhoff Brett L. , Belt Brian A. , Zhu Yu , Sanford Dominic E. , Belaygorod Larisa , Carpenter Danielle , Collins Lynne , Piwnica-Worms David , Hewitt Stephen , Udupi Girish Mallya , Gallagher William M. , Wegner Craig , West Brian L. , Wang-Gillam Andrea , Goedegebuure Peter , Linehan David C. , DeNardo David G.
Published: April 2023

PDF file - 91K
Supplementary Figures 1 - 3 from Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses
Authors: Mitchem Jonathan B. , Brennan Donal J. , Knolhoff Brett L. , Belt Brian A. , Zhu Yu , Sanford Dominic E. , Belaygorod Larisa , Carpenter Danielle , Collins Lynne , Piwnica-Worms David , Hewitt Stephen , Udupi Girish Mallya , Gallagher William M. , Wegner Craig , West Brian L. , Wang-Gillam Andrea , Goedegebuure Peter , Linehan David C. , DeNardo David G.
Published: April 2023

PDF file - 177K, Targeting TAMs decreases TICs. Macrophages directly promote chemoresistance. Efficacy of targeting CSF1R in combination with chemotherapy.
Supplementary Table 3 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Table 3 � XLXS file 39K, Patient/xenograft biomarker comparison
Supplementary Table 2 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Table 2 � XLXS file 18K, STR Results
Supplementary Table 11 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Table 11 � XLXS file 36K, Treatment response concordance between patient and xenograft
Supplementary Table 10 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Table 10 � XLXS file 35K, Metastasis rates in xenograft lines
Supplementary Fig 3 from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Supplementary Fig 3 � PDF file 31K, Demonstration of histological stability
Supplementary Figure 3 from Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics
Authors: Luo Ming , Zhao Xiaofeng , Chen Song , Liu Suling , Wicha Max S. , Guan Jun-Lin
Published: April 2023

PDF file, 492K, Genotyping of recipient mammary fat pads following transplantation as well as TUNEL assay for luminal and basal acini sections derived from Ctrl, MFCKO, and MFCKD mice.
Supplementary Figures 1 - 2 from IL-18–Primed Helper NK Cells Collaborate with Dendritic Cells to Promote Recruitment of Effector CD8+ T Cells to the Tumor Microenvironment
Authors: Wong Jeffrey L. , Berk Erik , Edwards Robert P. , Kalinski Pawel
Published: April 2023

PDF file - 40K, Chemokine receptor expression on peripheral blood-isolated DCs (S1); IL-18 synergizes with K562 tumor cell recognition in inducing NK cell expression of DC-attracting chemokines (S2).
Supplementary Figure Legends from Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway
Authors: Aggarwal Monika , Banerjee Taraswi , Sommers Joshua A. , Iannascoli Chiara , Pichierri Pietro , Shoemaker Robert H. , Brosh Robert M.
Published: April 2023

PDF file, 108K.
Supplementary Figure 3 from Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924
Authors: Blank Jonathan L. , Liu Xiaozhen J. , Cosmopoulos Katherine , Bouck David C. , Garcia Khristofer , Bernard Hugues , Tayber Olga , Hather Greg , Liu Ray , Narayanan Usha , Milhollen Michael A. , Lightcap Eric S.
Published: April 2023

PDF file - 121K, Distribution and Reproducibility of Scores from SMARTpool Interactions with MLN4924 in A375 Melanoma Cell Line
Supplementary Table 2 from FGFR4 Promotes Stroma-Induced Epithelial-to-Mesenchymal Transition in Colorectal Cancer
Authors: Liu Rui , Li Jingyi , Xie Ke , Zhang Tao , Lei Yunlong , Chen Yi , Zhang Lu , Huang Kai , Wang Kui , Wu Hong , Wu Min , Nice Edouard C. , Huang Canhua , Wei Yuquan
Published: April 2023

PDF file, 71K, Clinico-pathologic parameters of colorectal cancer patients.