bluuebunny/crossref_metadata_2025 huggingface dataset:
The Triglycerides and Glucose (TyG) Index Is Associated with 1-Hour Glucose Levels during an OGTT
Authors: Massimino Mattia , Monea Giuseppe , Marinaro Giuseppe , Rubino Mariangela , Mancuso Elettra , Mannino Gaia Chiara , Andreozzi Francesco
Published: January 2023

Background and Objectives: Among individuals with normal glucose tolerance (NGT), subjects with high levels of plasma glucose (≥155 mg/dL) at sixty minutes during an oral glucose tolerance test (1h-OGTT) are at an increased risk of developing type 2 diabetes. We investigated the association between the triglycerides and glucose (TyG) index, a novel marker of insulin resistance, with 1h-OGTT glucose plasma concentrations. Material and Methods: 1474 non-diabetic Caucasian subjects underwent a 75 g OGTT and were divided into two groups according to the cutoff 1h-OGTT plasma glucose < 155 mg/dL (NGT-1h-low) and ≥ 155 mg/dL (NGT-1h-high). The TyG index was calculated as ln [fasting triglycerides (milligrams per deciliter) × fasting blood glucose (milligrams per deciliter)/2]. Multivariable linear and logistic regression analyses were used to establish the contribution of the TyG index to the variability of 1h-OGTT glucose, and how the former affected the risk of being NGT-1h-high. Results: 1004 individuals were NGT-1h-low and 470 were NGT-1h-high. The TyG index was higher for NGT-1h-high (p = 0.001) individuals, and it was an independent factor influencing 1h-OGTT glycemia (β = 0.191, p < 0.001) after correcting for age, sex, and BMI. The TyG index was the strongest marker associated with the risk of being NGT-1h-high (OR = 1.703, CI 95% 1.34–2.17, p < 0.001) when compared with FPG (OR = 1.054, CI 95% 1.04–1.07, p < 0.001) and the HOMA-IR (OR = 1.156, CI 95% 1.08–1.23, p < 0.001). Conclusions: Our study demonstrated that the TyG index, an efficient and cost-effective marker of insulin resistance, is associated with the variability of early post-challenge glucose levels and is an independent marker of being NGT-1h-high.
Welfare Implications of Border Carbon Adjustments on the Trade of Harvested Wood Products
Authors: Liao Xinxin , Ning Zhuo
Published: January 2023

Border carbon adjustments (BCAs) are designed to regulate carbon emissions and reduce carbon leakage. Thus far, BCAs are mainly applied to imported carbon-intensive products. On the other hand, harvested wood products (HWPs) are the extension of forest carbon stocks, whose changes affect a country’s carbon stock level. Nonetheless, the trade of HWPs also raises the problem of carbon leakage when their carbon stocks are exported, which can be partially solved by applying export BCAs. We construct a two-stage game model to analyze the strategy changes of the government and forestry companies under BCAs: the first stage is output competition in a Cournot game similar to the trade of HWPs between New Zealand and China; the second stage is the setting of the tax rate of BCAs by the country. We use the inverse solution method to derive the results of the game. Our results find that the government imposes BCAs on exports of HWPs when the carbon stock value exceeds a threshold. Moreover, the export BCAs on HWPs can effectively reduce the amount of HWPs exported. The results also show that BCAs diminish forestry exporters’ revenues and consumer surplus while having no significant detrimental impact on a country’s welfare. BCAs help include carbon stock values into HWPs’ prices and reduce carbon leakage, which is beneficial for climate change. Thus, exporting countries can maintain their welfare by implementing BCAs, and the forestry companies can respond by improving product quality, enhancing product uniqueness, and reducing production costs.
The Role of Nutrition and Forest-Bathing in the Physical Rehabilitation of Physically Inactive Patients: From the Molecular Aspects to New Nature-Inspired Techniques
Authors: Baker Steven , Gilhen-Baker Melinda , Roviello Giovanni N.
Published: January 2023

Physical rehabilitation plays a fundamental role in the management of individuals with disabilities associated with age-related muscle loss or affected by catastrophic conditions such as trauma, surgery, cancer or other severe pathologies. These events have in common an extended period of physical inactivity. Patients who undergo prolonged bed rest often present with a number of complications; for example, muscle loss that can exacerbate existing conditions determined by sarcopenia, which in turn greatly limits physical functions. The main scope of this work is to summarize certain key strategies for the physiotherapeutic management of physically inactive patients, regardless of the reason behind their prolonged bed rest, with a particular focus on physical rehabilitation, nutrition and forest-bathing. The importance of correct nutrition in counter-acting the loss of muscle mass and consequent function is explored alongside a description of the main nutrients that are needed for muscle regeneration. From a biomolecular perspective, some specific molecular mechanisms associated with physical rehabilitation are also reported not only in the context of physical therapy, but also within nature-inspired techniques, such as forest-bathing as well as body self-healing. Combining a targeted physiotherapeutic approach with an appropriate diet as well as nature-based therapy could thus help with the recovery of bed ridden patients.
Effect of Arbuscular Mycorrhiza Fungus Diversispora eburnea Inoculation on Lolium perenne and Amorpha fruticosa Growth, Cadmium Uptake, and Soil Cadmium Speciation in Cadmium-Contaminated Soil
Authors: Sun Jiahua , Jia Qiong , Li Yi , Dong Kanglong , Xu Shuai , Ren Yanan , Zhang Ting , Chen Jiayuan , Shi Nannan , Fu Shenglei
Published: January 2023

Cadmium (Cd) pollution has become aggravated during the past decades of industrialization, severely endangering human health through its entry into the food chain. While it is well understood that arbuscular mycorrhizal fungi (AMF) have a strong ability to regulate plant growth and Cd uptake, studies investigating how they affect soil Cd speciation and influence Cd uptake are limited. We designed a pot experiment comprising two AMF-inoculant groups (inoculation with Diversispora eburnea or no inoculation), three Cd concentration levels (0, 5, and 15 mg/kg), and two plant species (Lolium perenne and Amorpha fruticosa) to study the effect of AMF Diversispora eburnea on plant growth, Cd uptake, and Cd speciation in the soil. The results revealed that L. perenne exhibited higher productivity and greater Cd uptake than A. fruticosa, regardless of AMF D. eburnea inoculation. However, AMF D. eburnea significantly altered soil Cd speciation by increasing the proportion of exchangeable Cd and decreasing residual Cd, resulting in Cd enrichment in the plant root organs and the elimination of Cd from the polluted soils. Our experiments demonstrate that inoculating plants with AMF D. eburnea is an effective alternative strategy for remediating Cd-contaminated soil.
Gender Discrimination Insights in Romanian Accounting Organisations
Authors: Faragalla Widad Atena , Tiron-Tudor Adriana , Stanca Liana , Deliu Delia
Published: January 2023

The paper investigated gender inequalities in the accounting profession in the specific context of an eastern European country, in the past heavily dominated by men, but now with a substantial number of women. Thus, we used a questionnaire survey explored the relationship between women’s perception of discrimination and institutional and individual characteristics. Institutional factors such as rewards practices, opportunities, and access to top positions in organisations influence women’s perception of gender discrimination. Concerning the intersectionality of individual characteristics interaction, our results revealed that women professionals with higher academic achievement and children are more likely to report discrimination. In contrast, women professionals with a higher-ranking position in organisations and those working in the public sector are less likely to report it compared with those from the private sector. These findings are of interest from a theoretical perspective to those who explore gender-related issues in general and in the case of accounting organisations. They are also helpful from a practical standpoint regarding the management of these accounting organisations, which should ensure gender-equitable policies for employees.
The Time-Lag Effect of Climate Factors on the Forest Enhanced Vegetation Index for Subtropical Humid Areas in China
Authors: Qin Jushuang , Ma Menglu , Shi Jiabin , Ma Shurui , Wu Baoguo , Su Xiaohui
Published: January 2023

Forests represent the greatest carbon reservoir in terrestrial ecosystems. Climate change drives the changes in forest vegetation growth, which in turn influences carbon sequestration capability. Exploring the dynamic response of forest vegetation to climate change is thus one of the most important scientific questions to be addressed in the precise monitoring of forest resources. This paper explores the relationship between climate factors and vegetation growth in typical forest ecosystems in China from 2007 to 2019 based on long-term meteorological monitoring data from six forest field stations in different subtropical ecological zones in China. The time-varying parameter vector autoregressive model (TVP-VAR) was used to analyze the temporal and spatial differences of the time-lag effects of climate factors, and the impact of climate change on vegetation was predicted. The enhanced vegetation index (EVI) was used to measure vegetation growth. Monthly meteorological observations and solar radiation data, including precipitation, air temperature, relative humidity, and photosynthetic effective radiation, were provided by the resource sharing service platform of the national ecological research data center. It was revealed that the time-lag effect of climate factors on the EVI vanished after a half year, and the lag accumulation tended to be steady over time. The TVP-VAR model was found to be more suitable than the vector autoregressive model (VAR). The predicted EVI values using the TVP-VAR model were close to the true values with the root mean squares error (RMSE) < 0.05. On average, each site improved its prediction accuracy by 14.81%. Therefore, the TVP-VAR model can be used to analyze the relationship of climate factors and forest EVI as well as the time-lag effect of climate factors on vegetation growth in subtropical China. The results can be used to improve the predictability of the EVI for forests and to encourage the development of intensive forest management.
Association between Leisure-Time and Commute Physical Activity and Pre-Diabetes and Diabetes in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Authors: Sánchez-Martínez Yuri , Goulart Alessandra , de Almeida-Pititto Bianca , Duncan Bruce , Schmidt Maria , Santos Itamar , Lotufo Paulo , Tebar William , Benseñor Isabela
Published: January 2023

Background: Diabetes is an important public health problem due to its health impairments and high costs for health services. We analyzed the relationship between the domains of physical activity at leisure-time (LTPA) and at commuting (CPA) with diabetes and pre-diabetes in an ELSA-Brasil study. Methods: Data from 11,797 participants (52.5% women, 49.1 ± 7.2 years) were analyzed. LTPA and CPA were measured using the International Physical Activity Questionnaire. Diabetes and pre-diabetes were defined by medical history, medication use to treat diabetes or blood glucose. Logistic regression models were performed to estimate the association between LTPA and CPA with diabetes and pre-diabetes after adjustment for sociodemographic and cardiovascular risk factors. Results: The prevalence of LTPA and CPA was 24.4% and 34%, respectively. Physically active participants at LTPA were less likely to have pre-diabetes (OR = 0.86 [95% CI = 0.77–0.95]) and diabetes (OR = 0.80 [95% CI = 0.69–0.93]), compared with inactive participants. No association between CPA and diabetes/pre-diabetes was observed. LTPA was inversely associated with diabetes among men (OR = 0.73 [95% CI = 0.60–0.89]), but was not associated among women. Women who were active (OR = 0.78 [95% CI = 0.67–0.90]) (OR = 0.79 [95% CI = 0.65–0.95]) at LTPA were less likely to have pre-diabetes, than inactive women. Conclusion: LTPA was inversely associated with diabetes and pre-diabetes in the ELSA-Brasil participants. A different behavior was observed between genders.
The Influence of Parental Mindfulness on Preschool Child Behavior Problems: A Chain-Mediated Model Analysis
Authors: Quan Hehong , He Jingyu , Li Chun
Published: January 2023

This study aimed to examine the associations between parental mindfulness and preschool child behavior problems and to investigate the mediating role of marital satisfaction and coparenting in the relationship between mindfulness and preschool child behavior problems. This was a cross-sectional study in which general sociodemographic data were obtained from 3448 parents of children in grades junior to senior of kindergarten who were assessed using instruments such as the Mindful Attention Awareness Scale (MAAS), the Strengths and Difficulties Questionnaire (SDQ), the ENRICH Marital Satisfaction Scale (TEMSS), and the Parents’ Perceptions of the Coparenting Relationship Questionnaire (PPCR). (1) Mindfulness, preschool child behavior problems, marital satisfaction, and coparenting were significantly correlated with each other, where mindfulness was positively correlated with marital satisfaction and coparenting and significantly negatively correlated with preschool child behavior problems. (2) Mindfulness negatively predicted preschool children’s problem behaviors. (3) Marital satisfaction independently mediated the relationship between mindfulness and preschool child behavior problems. (4) Coparenting also independently mediated the relationship between mindfulness and preschool child behavior problems. (5) Marital satisfaction and coparenting play a chain-mediating role between mindfulness and preschool children’s problem behaviors. Mindfulness predicted preschool child behavior problems, with marital satisfaction and coparenting as mediators.
Community Perceptions of Arsenic Contaminated Drinking Water and Preferences for Risk Communication in California’s San Joaquin Valley
Authors: Boyden Hollynd , Gillan Mayela , Molina Javier , Gadgil Ashok , Tseng Winston
Published: January 2023

Due to chronic exposure to elevated levels of arsenic in drinking water, thousands of Californians have increased risk for internal cancers and other adverse health effects. The mortality risk of cancer is 1 in 400 people exposed to above 10 μg/L of arsenic in their drinking water. The purpose of this community assessment was to understand the perceptions and awareness of the residents and public water representatives in rural, unincorporated farming communities of color in San Joaquin Valley, California. In our research, we asked 27 community informants about their (1) available water sources, (2) knowledge about the health impacts of arsenic, and (3) preferences for risk communication and education regarding the health impacts of arsenic-contaminated drinking water. Through our qualitative coding and analysis, we found that most community informants indicated that there was limited community awareness about the health effects of drinking water with elevated arsenic levels. Preferences for risk communication included using in-language, culturally relevant, and health literate health promotion strategies and teaching these topics through the local K-8 schools’ science curriculum with a language brokerage approach to transfer student knowledge to family members. Key recommendations include implementing these communication preferences to increase community-wide knowledge about safe drinking water.
Exploring Extreme Weather and Recess Policies, Practices, and Procedures in the Canadian Context
Authors: Button Brenton L. G. , Martin Gina
Published: January 2023

The purpose of this study was to explore the different policies, practices, and procedures that are used on weather and recess in the Canadian context. Fifty school websites were examined, and ten key informants were interviewed. Policies, practices, and procedures from school websites were downloaded, and interviews were transcribed verbatim and analyzed using a qualitative content analysis. Fourteen schools had an outwardly facing policy, practice, or procedure for weather and recess. Cold temperatures were the most often cited reason for modifying recess to be indoors, with temperatures ranging from −20 to −40 for complete indoor recess. Precipitation was only found in four online documents but was mentioned as a reason to modify recess by all key informants. Additionally, key informants discussed variability in how recess policies, practices, and procedures were followed. The findings of this study illustrate inconsistencies in both formal and informal school weather and recess policies. With outdoor recess providing numerous opportunities to improve various domains of well-being, it is pertinent to understand the conditions on which it is being modified.
Assessing Perception of Wildfires and Related Impacts among Adult Residents of Southern California
Authors: Masri Shahir , Shenoi Erica Anne , Garfin Dana Rose , Wu Jun
Published: January 2023

Major wildfires and their smoke pose a threat to public health and are becoming more frequent in the United States, particularly in California and other populated, fire-prone states. Therefore, it is crucial to understand how California residents view wildfires and engage in risk-reducing behaviors during wildfire events. Currently, there is a knowledge gap concerning this area of inquiry. We disseminated a 40-question cross-sectional survey to explore wildfire perception and knowledge along with related risk-reducing measures and policies among 807 adult residents in the fire-prone region of Orange County, California. Results demonstrated that nearly all (>95%) participants had (or knew someone who had) previously experienced a wildfire. Female gender, knowing a wildfire victim and reporting to have a general interest/passion for environmental issues were the three factors most strongly associated with (1) wildfires (and smoke) being reported as a threat, (2) participants’ willingness to evacuate if threatened by a nearby wildfire, and (3) participants’ willingness to support a wildfire-related tax increase (p < 0.05). The majority (57.4%) of participants agreed that the occurrence of wildfires is influenced by climate change, with the most commonly reported risk-reducing actions (by 44% of participants) being informational actions (e.g., tracking the news) rather than self-motivated physical safety actions (e.g., using an air purifier) (29%). The results of this study can help to inform decision- and policy-making regarding future wildfire events as well as allow more targeted and effective public health messaging and intervention measures, in turn helping to reduce the risk associated with future wildfire/smoke episodes.
Effect of Amnioguard and Biomesh GTR Membranes with Novabone Putty in the Treatment of Periodontal Osseous Defects—A Communication
Authors: Chakraborthy Priyankar , Ravishankar Potluri Leela , Saravanan Anbukumari Vadivelu , Alzahrani Khalid J. , Halawan Ibrahim F. , Alshammeri Saleh , Alnfiai Mrim M. , Baeshen Hosam Ali , Qattan Sarah Yasser M. , Almarghlani Ammar , Karkala Sunanda Rao , Neelakandan Anila , Patil Shankargouda
Published: January 2023

(1) Background: Guided tissue regeneration was an effective surgical procedure in the management of intrabony defects and has undergone a number of changes in terms of materials and techniques. The aim of this study is to compare AmnioGuard and BioMesh in combination with NovaBone putty in intrabony defects. (2) Methodology: Ten patients who needed regenerative periodontal therapy were randomly allocated into two groups based on the inclusion criteria. These patients were subjected to phase I therapy followed by which Group A patients were treated with AmnioGuard + NovaBone putty whereas Group B with BioMesh + NovaBone putty. The clinical indices were obtained at baseline, 3 months and 6 months post-operatively while radiographic parameters were obtained at 6 months post-op. (3) Results & Conclusion: At six months after surgery, Group B (33% bone gain) showed a statistically significant change from Group A (16% bone gain) in both the clinical and radiographic measures (p < 0.05).
Acute Effects of Fitlight Training on Cognitive-Motor Processes in Young Basketball Players
Authors: Silvestri Fioretta , Campanella Matteo , Bertollo Maurizio , Albuquerque Maicon Rodrigues , Bonavolontà Valerio , Perroni Fabrizio , Baldari Carlo , Guidetti Laura , Curzi Davide
Published: January 2023

Cognitive-motor training could be used to improve open-skill sport performances, increasing cognitive demands to stimulate executive function (EF) development. Nevertheless, a distributed training proposal for the improvement of EFs is increasingly difficult to combine with seasonal sport commitments. This study aimed to investigate whether a massed basketball training program enriched with Fitlight training can improve EFs and motor performance. Forty-nine players (age = 15.0 ± 1.5 yrs) were assigned to the control and Fitlight-trained (FITL) groups, which performed 3 weeks of massed basketball practice, including 25 min per day of shooting sessions or Fitlight training, respectively. All athletes were tested in cognitive tasks (Flanker/Reverse Flanker; Digit Span) and fitness tests (Agility T-test; Yo-Yo IR1). During the intervention, exercise/session perceived effort (eRPE/sRPE) and enjoyment were collected. RM-ANOVA showed significant EFs scores increased in both groups over time, without differences between the groups. Moreover, an increased sRPE and eRPE appeared in the FITL group (p = 0.0001; p = 0.01), with no group differences in activity enjoyment and fitness tests. Three weeks of massed basketball training improved EFs and motor performance in young players. The additional Fitlight training increased the perceived cognitive effort without decreasing enjoyment, even if it seems unable to induce additional improvements in EFs.
Spatial Human Development Index in China: Measurement and Interpretation Based on Bayesian Estimation
Authors: Luo Xiang , Qin Jingjing , Wan Qing , Jin Gui
Published: January 2023

The development of urban agglomerations dominated by the service industry is an important driving force for further sustainable economic growth of China. Spatial analysis marked by population density and regional integration is an essential perspective for studying the human development index (HDI) in China. Based on Bayesian estimation, this paper examines the influence of a spatial factor on HDI by using a spatial hierarchical factor model within the framework of Sen Capability Approach theory, overcoming the neglect of spatial factors and their equal weight in traditional measurement of HDI. On this basis, the HDI including the spatial factor was measured based on the panel data from 2000 to 2018. The results reveal that (1) provinces with high population densities and regional integration have higher rankings and low uncertainties of HDI, which can be attributed to the improvement of education weights; (2) HDI has a certain spatial spillover effect, and the spatial association increases year by year; (3) robust test by using nighttime lighting as an alternative indicator of GDP supports that the spatial correlation is positively related to HDI ranking. The policy recommendations of this paper are to remove the obstacles for cross-regional population mobility and adjust the direction and structure of public expenditure.
Association of Soyfoods or Soybean Products Consumption with Psychological Symptoms: Evidence from a Cross-Sectional Study of Chinese University Students during the COVID-19 Pandemic
Authors: Li Shengpeng , Liu Cong , Song Yongjing , Ma Nan , Lu Jinkui
Published: January 2023

There is a strong association between soyfoods or soybean product consumption and adolescent health, but there are few studies on the association between soyfoods or soybean product consumption and psychological symptoms among university students. To this end, this study investigated the association between soyfoods or soybean products consumption and psychological symptoms among Chinese university students and analyzed the association between them. A three-stage stratified whole-group sampling method was used to administer questionnaires on soyfoods or soybean products consumption and psychological symptoms to 7742 university students in China. Self-assessment questionnaires were also administered to confounding variables such as basic demographic information, family status, parental education, body mass index (BMI), and moderate and vigorous physical activity (MVPA). The chi-square test, one-way ANOVA, and logistic regression analysis were used to explore the association and differences between soyfoods or soybean products consumption and psychological symptoms. The proportion of Chinese university students’ soyfoods or soybean products consumption in ≤one time/week, two–four times/week, and ≥five times/week were 38.81%, 40.24%, and 20.95%, respectively. University students’ psychological symptoms problem detection rate was 16.22%. The detection rate of psychological symptoms was lower among university male students (14.75%) than female students (17.35%), and the difference was statistically significant (χ2 = 9.525, p < 0.01). After adjusting for relevant covariates, students with soyfoods or soybean products consumption ≤one time/week (OR = 1.83, 95% CI:1.52, 2.21) had a higher risk of psychological symptoms compared to university students with soyfoods or soybean products consumption ≥five time/week (p < 0.01). During the COVID-19 pandemic, Chinese university students had lower consumption of soyfoods or soybean products and a higher detection rate of psychological symptoms. There was a negative association between soyfoods or soybean products consumption and psychological symptoms. Our study provides a scientific reference for the government and educational decision-making authorities and suggests that education on eating behavior and dietary guidance should be emphasized among university students in the future to maintain a reasonable consumption of soyfoods or soybean products for better physical and mental health development.
Raising Suicide in Medical Appointments—Barriers and Facilitators Experienced by Young Adults and GPs: A Mixed-Methods Systematic Review
Authors: Osborne Debra , De Boer Kathleen , Meyer Denny , Nedeljkovic Maja
Published: January 2023

The aim of this review was to understand the barriers and facilitators facing GPs and young adults in raising and addressing suicide in medical appointments. A mixed-methods systematic review was conducted of qualitative and quantitative studies. The focus was papers that explored barriers and facilitators experienced by young adults aged 18 to 26, and GPs working in primary care environments. Nine studies met the inclusion criteria. Four studies provided information on young adults’ views, four on GPs, and one considered both GP and young adults’ viewpoints. Nine barrier and seven facilitator themes were identified. Unique to this review was the recognition that young adults want GPs to initiate the conversation about suicide. They see this as a GP’s responsibility. This review further confirmed that GPs lack the confidence and skills to assess suicide risk in young adults. Both findings combined could explain previous results for reduced identification of suicide risk in this cohort. GP training needs considerable focus on addressing skill deficiencies and improving GP confidence to assess suicide risk. However, introducing suicide risk screening in primary care for young adults should be a priority as this will overcome the need for young adults to voluntarily disclose thoughts of suicide.
Bibliometric Analysis in the Field of Rural Revitalization: Current Status, Progress, and Prospects
Authors: Liu Leng , Cao Congjie , Song Wei
Published: January 2023

Rural areas play an important role in global sustainable development. In recent years, however, rural development has experienced global crises, such as issues in public education, health care, roads, water and sanitation, along with environmental pollution and a lack of natural resources. It is therefore important to promote rural revitalization in the process of modernization. To objectively reveal the current research status in the field of rural revitalization, we analyzed relevant publications in the Web of Science from 1991 to 2021. The results are as follows: (1) In the past 30 years, the number of publications on rural vitalization has increased, and the period from 1991 to 2021 can be divided into three stages, the initial period (1991–2004), the development period (2005–2016), and the high-yield period (2017–2021). (2) Research on rural revitalization covered 60 countries or regions around the world, involving a total of 3099 authors. China, the United States, and Canada published most of the articles. (3) High-frequency keywords were migration, management, and urbanization, indicating that scientists considered the role of sustainable urban and rural development, policy formulation, and urbanization. We highlight that for the development of the field of rural vitalization, scientists need to further strengthen theoretical research, fully absorb the development achievements of advanced countries and regions, understand the laws and trends of urban and rural development in their own countries, and explore new paths to achieve rural vitalization.
Predictors of Mental Health Literacy among Parents, Guardians, and Teachers of Adolescents in West Malaysia
Authors: Phoa Picholas Kian Ann , Ab Razak Asrenee , Kuay Hue San , Ghazali Anis Kausar , Ab Rahman Azriani , Husain Maruzairi , Bakar Raishan Shafini , Abdul Gani Firdaus
Published: January 2023

Parents, guardians, and teachers are the informal sources of mental health support that adolescents rely on. Nevertheless, limited mental health knowledge limits their ability and confidence in providing appropriate assistance. This study aims to (1) evaluate the relationship between the roles of parents/guardians and teachers and their responses to discover the common misconceptions on mental health among those providing informal support to adolescents and (2) determine which demographic factors would act as the strongest predictor influencing their mental health literacy (MHL) status. The cross-sectional study recruited 867 parents, guardians, and teachers of adolescents from 24 government secondary schools’ parent–teacher associations via multistage stratified random sampling. Parents, guardians, and teachers’ MHL were evaluated using the Mental Health Knowledge Schedule—Malay Version (MAKS-M). The collected data were analyzed using Pearson’s Chi-squared test to investigate the association between the respondents’ roles and responses. Multiple Regression analysis was used to determine the predictors of MHL. The score of MAKS-M for the current study sample is 73.03% (M = 43.82, SD = 4.07). Most respondents responded incorrectly on Items 1 (employment), 6 (help-seeking), 8 (stress), and 12 (grief). Teachers provided more favorable responses on several items than parents and guardians. Finally, younger age, higher income, knowing someone with mental disorders, and having experience of attending formal training on mental health first aid were the significant predictors of MHL. MHL interventions in Malaysia should cater to older adults of lower socioeconomic status and lesser experience in mental health, specifically highlighting the stigmas on mental health help-seeking behaviors, treatment, and employment concerns, plus the recognition of various mental health diagnoses.
An Integrated System of Multifaceted Machine Learning Models to Predict If and When Hospital-Acquired Pressure Injuries (Bedsores) Occur
Authors: Dweekat Odai Y. , Lam Sarah S. , McGrath Lindsay
Published: January 2023

Hospital-Acquired Pressure Injury (HAPI), known as bedsore or decubitus ulcer, is one of the most common health conditions in the United States. Machine learning has been used to predict HAPI. This is insufficient information for the clinical team because knowing who would develop HAPI in the future does not help differentiate the severity of those predicted cases. This research develops an integrated system of multifaceted machine learning models to predict if and when HAPI occurs. Phase 1 integrates Genetic Algorithm with Cost-Sensitive Support Vector Machine (GA-CS-SVM) to handle the high imbalance HAPI dataset to predict if patients will develop HAPI. Phase 2 adopts Grid Search with SVM (GS-SVM) to predict when HAPI will occur for at-risk patients. This helps to prioritize who is at the highest risk and when that risk will be highest. The performance of the developed models is compared with state-of-the-art models in the literature. GA-CS-SVM achieved the best Area Under the Curve (AUC) (75.79 ± 0.58) and G-mean (75.73 ± 0.59), while GS-SVM achieved the best AUC (75.06) and G-mean (75.06). The research outcomes will help prioritize at-risk patients, allocate targeted resources and aid with better medical staff planning to provide intervention to those patients.
Persistent Increase of Sympathetic Activity in Post-Acute COVID-19 of Paucisymptomatic Healthcare Workers
Authors: Liviero Filippo , Scapellato Maria Luisa , Folino Franco , Moretto Angelo , Mason Paola , Pavanello Sofia
Published: January 2023

Healthcare workers (HCWs) represent a population with a significant burden of paucisymptomatic COVID-19, as the general population. We evaluated autonomic nervous system activity by means of heart rate variability (HRV) in HCWs during health surveillance visits. Short-term electrocardiogram (ECG) recordings were obtained 30 days (IQR 5.25–55.75) after a negative naso-pharyngeal swab for SARS-CoV-2 in 44 cases and compared with ECGs of 44 controls with similar age and sex distribution. Time and frequency domain HRV were evaluated. HCWs who used drugs, had comorbidities that affected HRV, or were hospitalized with severe COVID-19 were excluded. Frequency domain HRV analysis showed a significantly higher low/high-frequency power ratio (LF/HF) in the case study compared with controls (t = 2.84, p = 0.006). In time domain HRV analysis, mean standard deviation of normal-to-normal intervals (SDNN) and root mean square of successive RR interval differences (RMSSD) were significantly lower for cases compared with controls (t = −2.64, p = 0.01 and t = −3.27, p = 0.002, respectively). In the post-acute phase of infection, SARS-CoV-2 produces an autonomic imbalance mirrored by a reduction in HRV. These results are consistent with epidemiological data that suggest a higher risk of acute cardiovascular complications in the first 30 days after COVID-19 infection.
Health Literacy, Social Networks, and Health Outcomes among Mental Health Clubhouse Members in Hawai‘i
Authors: Agner Joy , Meyer Monet , Kaukau Tyra Mahealani , Liu Maileen , Nakamura Lisa , Botero Adriana , Sentell Tetine
Published: January 2023

Health literacy is the ability to obtain and utilize health information to make health-related decisions and to navigate health systems. Although health literacy has traditionally been understood as an individual-level construct, current research is revealing the impact that social networks can have on health literacy. To date, no studies have examined associations between health literacy and social networks among people with serious mental illness (PWSMI), who are at high risk of physical illness and premature mortality. To begin to fill this gap, this study explores associations between health literacy, relationships with health discussion partners, and self-reported health outcomes in a racially diverse sample of Clubhouse members in Hawai‘i. Clubhouses are community mental health centers that promote recovery from mental illness through destigmatization, meaningful activity, and strong social relationships. Health literacy was assessed using two single-item screeners (SILS). In a sample of 163 members, 56.2% reported adequate ability to understand health-related instructions or pamphlets, and 43.3% reported adequate confidence filling out medical forms independently. This is consistent with other health literacy studies with PWSMI in the United States, and indicates lower health literacy within this group than is reported in national averages. Multivariate logistic regression revealed a larger Clubhouse staff social network and completing high school were significantly associated with requiring less help to read materials. Higher age, male gender, and being Native Hawaiian and/or Pacific Islander were associated with less confidence filling out medical forms, while higher self-efficacy was associated with higher confidence filling out medical forms. This study provides preliminary evidence that relationships fostered within Clubhouses are associated with health literacy among PWSMI, and highlights the need for more research to examine how social networks and health literacy interventions can be leveraged in community mental health settings to improve health outcomes within this vulnerable population.
Musculoskeletal Disorder Burden and Its Attributable Risk Factors in China: Estimates and Predicts from 1990 to 2044
Authors: Yu Zeru , Zhang Jingya , Lu Yongbo , Zhang Ning , Wei Bincai , He Rongxin , Mao Ying
Published: January 2023

Musculoskeletal disorders are one of the three major disabling diseases in the world. However, the current disease burden in China is not well-known. This study aimed to explore the burden and risk factors of musculoskeletal disorders in China from 1990 to 2019, predicting the incidence trend from 2020 to 2044. All data were extracted from the Global Burden of Disease Study 2019 (GBD 2019). Joinpoint regression and age–period–cohort (APC) models were selected to analyze the epidemic trend, and descriptive analyses of the time trends and age distributions of risk factors were performed. The Bayesian APC model was used to foresee the incidence trend from 2020 to 2044. The results indicated that the burden of musculoskeletal disorders is higher in women and older adults. Its attributable risk factors were found to be tobacco, a high body mass index, kidney dysfunction and occupational risks. In 2044, musculoskeletal disorders in China showed a downward trend for 35–59-year-olds and a slight upward trend for 30–34- and 65–84-year-olds. The 70–74 year age group saw the largest increase in incidence at 4.66%. Overall, the incidence increased with age. Therefore, prevention and control policies should focus on women and the elderly, and health interventions should be carried out based on risk factors.
A Sensor Placement Strategy for Comprehensive Urban Heat Island Monitoring
Authors: Pathak Prasad , Pandya Pranav , Shukla Sharvari , Sane Aamod , Sengupta Raja
Published: January 2023

Urban heat islands (UHIs) increase the energy consumption of cities and impact the health of its residents. In light of the correlation between energy consumption and health and UHI variations observed at a local level within the canopy layer, satellite-derived land surface temperatures (LSTs) may be insufficient to provide comprehensive information about these deleterious effects. For both LST and air temperatures to be collected in a spatially representative and continuous manner, and for the process to be affordable, on-ground temperature and humidity sensors must be strategically placed. This study proposes a strategy for placing on-ground sensors that utilizes the spatial variation of measurable factors linked to UHI (i.e., seasonal variation in LSTs, wind speed, wind direction, bareness, and local climate zones), allowing for the continuous measurement of UHI within the canopy layer. As a representative city, Pune, India, was used to demonstrate how to distribute sensors based on the spatial variability of UHI-related variables. The proposed method may be helpful for any city requiring local-level observations of UHI, regardless of the climate zone. Further, we evaluate the placement of low-cost technology sensors that use LoRaWAN technology for this purpose, in order to overcome the problem of high costs associated with traditional in-situ weather stations.
Comparison of Long-Read Methods for Sequencing and Assembly of Lepidopteran Pest Genomes
Authors: Zhang Tong , Xing Weiqing , Wang Aoming , Zhang Na , Jia Ling , Ma Sanyuan , Xia Qingyou
Published: January 2023

Lepidopteran species are mostly pests, causing serious annual economic losses. High-quality genome sequencing and assembly uncover the genetic foundation of pest occurrence and provide guidance for pest control measures. Long-read sequencing technology and assembly algorithm advances have improved the ability to timeously produce high-quality genomes. Lepidoptera includes a wide variety of insects with high genetic diversity and heterozygosity. Therefore, the selection of an appropriate sequencing and assembly strategy to obtain high-quality genomic information is urgently needed. This research used silkworm as a model to test genome sequencing and assembly through high-coverage datasets by de novo assemblies. We report the first nearly complete telomere-to-telomere reference genome of silkworm Bombyx mori (P50T strain) produced by Pacific Biosciences (PacBio) HiFi sequencing, and highly contiguous and complete genome assemblies of two other silkworm strains by Oxford Nanopore Technologies (ONT) or PacBio continuous long-reads (CLR) that were unrepresented in the public database. Assembly quality was evaluated by use of BUSCO, Inspector, and EagleC. It is necessary to choose an appropriate assembler for draft genome construction, especially for low-depth datasets. For PacBio CLR and ONT sequencing, NextDenovo is superior. For PacBio HiFi sequencing, hifiasm is better. Quality assessment is essential for genome assembly and can provide better and more accurate results. For chromosome-level high-quality genome construction, we recommend using 3D-DNA with EagleC evaluation. Our study references how to obtain and evaluate high-quality genome assemblies, and is a resource for biological control, comparative genomics, and evolutionary studies of Lepidopteran pests and related species.
Cerebral Folate Metabolism in Post-Mortem Alzheimer’s Disease Tissues: A Small Cohort Study
Authors: Naz Naila , Naqvi Syeda F. , Hohn Nadine , Whelan Kiara , Littler Phoebe , Roncaroli Federico , Robinson Andrew C. , Miyan Jaleel A.
Published: January 2023

We investigated the cerebral folate system in post-mortem brains and matched cerebrospinal fluid (CSF) samples from subjects with definite Alzheimer’s disease (AD) (n = 21) and neuropathologically normal brains (n = 21) using immunohistochemistry, Western blot and dot blot. In AD the CSF showed a significant decrease in 10-formyl tetrahydrofolate dehydrogenase (FDH), a critical folate binding protein and enzyme in the CSF, as well as in the main folate transporter, folate receptor alpha (FRα) and folate. In tissue, we found a switch in the pathway of folate supply to the cerebral cortex in AD compared to neurologically normal brains. FRα switched from entry through FDH-positive astrocytes in normal, to entry through glial fibrillary acidic protein (GFAP)-positive astrocytes in the AD cortex. Moreover, this switch correlated with an apparent change in metabolic direction to hypermethylation of neurons in AD. Our data suggest that the reduction in FDH in CSF prohibits FRα-folate entry via FDH-positive astrocytes and promotes entry through the GFAP pathway directly to neurons for hypermethylation. This data may explain some of the cognitive decline not attributable to the loss of neurons alone and presents a target for potential treatment.
High-Throughput Strategies for the Design, Discovery, and Analysis of Bismuth-Based Photocatalysts
Authors: Prabhakar Vattikuti Surya V. , Zeng Jie , Ramaraghavulu Rajavaram , Shim Jaesool , Mauger Alain , Julien Christian M.
Published: January 2023

Bismuth-based nanostructures (BBNs) have attracted extensive research attention due to their tremendous development in the fields of photocatalysis and electro-catalysis. BBNs are considered potential photocatalysts because of their easily tuned electronic properties by changing their chemical composition, surface morphology, crystal structure, and band energies. However, their photocatalytic performance is not satisfactory yet, which limits their use in practical applications. To date, the charge carrier behavior of surface-engineered bismuth-based nanostructured photocatalysts has been under study to harness abundant solar energy for pollutant degradation and water splitting. Therefore, in this review, photocatalytic concepts and surface engineering for improving charge transport and the separation of available photocatalysts are first introduced. Afterward, the different strategies mainly implemented for the improvement of the photocatalytic activity are considered, including different synthetic approaches, the engineering of nanostructures, the influence of phase structure, and the active species produced from heterojunctions. Photocatalytic enhancement via the surface plasmon resonance effect is also examined and the photocatalytic performance of the bismuth-based photocatalytic mechanism is elucidated and discussed in detail, considering the different semiconductor junctions. Based on recent reports, current challenges and future directions for designing and developing bismuth-based nanostructured photocatalysts for enhanced photoactivity and stability are summarized.
Low Specificity but Dissimilar Mycorrhizal Communities Associating with Roots May Contribute to the Spatial Pattern of Four Co-Occurring Habenaria (Orchidaceae) Species
Authors: Zhang Wenliu , Gao Jiangyun , Shao Shicheng , Li Taiqiang
Published: January 2023

Fungi with orchid roots have been increasingly proven to play important roles in orchid growth, spatial distribution, and coexistence of natural communities. Here, we used 454 amplicon pyrosequencing with two different primer combinations to investigate the spatial variations in the community of OMF and endophytic fungi associates within the roots of four co-occurring Habenaria species. The results showed that all investigated Habenaria species were generalists and the different fungi communities may contribute to the spatial separation of the four Habenaria species. Firstly, the fungal OTUs identified in the roots of the four species overlapped but their presence differed amongst species and numerous distinct OMF families were unique to each species. Second, NMDS clustering showed samples clustered together based on associated species and PERMANOVA analyses indicated that fungi communities in the roots differed significantly between the Habenaria species, both for all endophytic fungi communities and for OMF communities. Third, the network structure of epiphytic fungi was highly specialized and modular but demonstrated lowly connected and anti-nested properties. However, it calls for more soil nutrition and soil fungal communities’ studies to elucidate the contribution of habitat-specific adaptations in general and mycorrhizal divergence.