bluuebunny/crossref_metadata_2025 huggingface dataset:
Lauburus, espirales y laberintos en los proyectos arquitectónicos de Jorge Oteiza
Authors: Sarasola Rubio Fátima
Published: March 2021

Al contemplar la obra de Jorge Oteiza, se abre ante nosotros un universo estético lleno de enlaces moleculares, sonemas, tartes, unidades Malevich, diedros, triedros y frontones vascos; crómlechs, círculos, esferas, huevos, espirales y laberintos, que el escultor analiza y entreteje, en su lucha por recuperar la herencia ancestral del hombre vasco.El contenido simbólico de estas imágenes arquetípicas y su gran valor plástico, conforman un “sustrato formal y mágico”, con el que el escultor trata de recomponer una compleja documentación, que conecta el proceso artístico desde la prehistoria vasca, hasta los movimientos del arte del siglo XX. Oteiza nunca abandona estas reflexiones, y espirales y laberintos le acompañan en la génesis de algunos de sus proyectos arquitectónicos como el de la Capilla en el Camino de Santiago, el Instituto Internacional de Investigaciones Estéticas Comparadas para San Juan de Luz o el del Cementerio de Ametzagaña, en San Sebastián.
Los proyectos no materializados del arquitecto Diego Méndez en el Real Sitio de El Pardo
Authors: Cantarero García Guadalupe
Published: March 2021

Entre la documentación inédita sobre el Real Sitio de El Pardo perteneciente al arquitecto Diego Méndez se encuentran en su archivo privado proyectos no publicados que nunca se llegaron a realizar.El presente artículo (1) describe estos proyectos y pone de manifiesto cómo éstos hubieran afectado al entramado histórico y al contexto paisajístico madrileño de haberse desarrollado así como cual hubiera sido la repercusión en un pueblo que deja de ser tal en el año 1951. Los planos aquí presentados han permitido vincular estos proyectos dentro del Plan de Ordenación Urbana de El Nuevo Pueblo de El Pardo (1941-1952).
Hemorrhages Seen on Brain Images After Mild Traumatic Brain Injury May Increase the Risk of Post-concussion Syndrome
Authors:   Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran, Eslamparast Seddigheh , Rehianian Zoheir ,   Neuroscience Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran, Ramezani Sara ,   epartment of Neurosurgery, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Published: March 2021

Background and Aim: Mild Traumatic Brain Injury (mTBI) mostly develops the symptoms that may persist for over three months known as Post-Concussion Syndrome (PCS). However, the PCS potential risk for mTBI victims is not well-identified. Here, we investigated the putative risk factors of PCS. Methods and Materials/Patients: In a cross-sectional study, we collected (HIS) the demographic, clinical, and radiological data using the hospital information system in 388 mTBI patients who passed at least 3 months since the onset of their injury and referred to Poursina hospital from March 2017 to December 2018. The patients were examined to diagnose PCS by a general physician using the phone interview via the Rivermead Post-concussion Symptoms Questionnaire (RPQ). The subjects were separated into groups with and without PCS. Data were analyzed by parametric t-test, Chi-square test and multiple logistic regression. Results: One-hundred ninety one out of 388 mTBI patients consented to complete the RPQ and around 59% of cases experienced PCS. There was no significant difference in the demographic variables and past medical history between groups. However, the previous psychological disease was particularly associated with PCS (P>0.043). Length of hospitalization, functional outcome during discharge, and post-resuscitation consciousness did not show any significant association with PCS (P<0.05). Interestingly, initial abnormal brain scan, fronto-temporal lesion, and accompanied hematoma (hemorrhages) were identified as risk factors of mTBI-induced PCS. The risk of PCS was found to increase by 7.2 times in mTBI patients demonstrated as an abnormality in their initial brain scans (P<0.001). A directly proportional relationship was found between the occurrence of the syndrome and the fronto-temporal lesion (P<0.017). Accompanied hematoma enhanced the risk of PCS by 2.6 times (P<0.04). Conclusion: This study emphasized the significance of early brain scan data for the prediction of PCS and the necessity of proper follow-up care for the at-risk population. The reported data from this study might be applied as an objective trajectory to measure PCS in those who simulated PCS for the litigation.
Hearing status of children under five years old in Jatinangor district
Authors: Wijana Wijana , Abrianto Frino , Boesoirie Shinta Fitri , Dermawan Arif
Published: March 2021

Background: Hearing is one of the most influential factors in children developmental process. The critical period of hearing and speech development begins in the first 6 months of life and continues until the age of 3 years. World Health Organization estimates that one to three in a thousand births have sensorineural hearing loss (SNHL). Early detection of hearing loss is substantial so that the diagnosis can be established and appropriate intervention can be done earlier. Purpose: To determine the hearing status in children under five years of age in Jatinangor. Method: A cross-sectional observational study with 240 subjects under the age of five in 12 Integrated Healthcare Center (Posyandu) in Jatinangor. Examinations included parental interviews, Behavioral Observation Audiometry (BOA), Otoacoustic Emissions (OAE), and tympanometry tests. Result: One child (0.4%) had moderate conductive hearing lossin the left ear, 1 child (0.4%) had bilateralsevere SNHL, and 7 children (2.9%) had profound bilateral SNHL. Conclusion: The incidence of hearing loss in children under five in Jatinangor was 3.8%, with bilateral profound SNHL asthe highest number, and the most common cause were prenatal Toxoplasma, Rubella, Cytomegalovirus (CMV) dan Herpes simplex virus (TORCH) infections.Keywords: children under-five, early detection, hearing status ABSTRAKLatar belakang: Pendengaran merupakan salah satu faktor yang sangat berpengaruh dalam proses perkembangan anak. Periode kritis perkembangan pendengaran dan berbicara dimulai dalam 6 bulan pertama kehidupan dan terus berlanjut sampai usia 3 tahun. Badan kesehatan dunia memperkirakan satu sampai tiga dalam seribu kelahiran terdapat kejadian gangguan dengar jenis sensorineural. Deteksi dini gangguan dengar penting untuk dilakukan sehingga diagnosis dapat ditegakkan dan intervensi yang tepat dapat dilakukan sedini mungkin. Tujuan: Untuk mengetahui status pendengaran pada anak usia bawah lima tahun di kecamatan Jatinangor. Metode: Penelitian observasional potong lintang dengan subjek penelitian 240 anak usia bawah lima tahun di 12 Pos Pelayanan Terpadu (Posyandu) Kecamatan Jatinangor. Dilakukan pemeriksaan meliputi wawancara orangtua anak, tes Behavioral Observation Audiometry (BOA), tes Otoacoustic Emissions (OAE) dan tes timpanometri. Hasil: Didapatkan 1 anak (0,4%) mengalami gangguan dengar konduktif derajat sedang pada telinga kiri, 1 anak (0,4%) mengalami gangguan dengar sensorineural derajat berat bilateral, dan 7 anak (2,9%) mengalami gangguan dengar sensorineural derajat sangat berat bilateral. Kesimpulan: Angka kejadian gangguan dengar pada balita di kecamatan Jatinangor sebesar 3,8% dengan gangguan dengar terbanyak berupa sensorineural derajat sangat berat bilateral, dan latar belakang penyebab terbanyak adalah infeksi prenatal Toxoplasma, Rubella, Cytomegalovirus dan Herpes simplex virus (TORCH).
KEPEMIMPINAN MOTIVASI DAN KOMPENSASI PENGARUHNYA TERHADAP KINERJA (STUDI PADA BADAN PENGELOLA PAJAK DAN RETRIBUSI DAERAH KOTA LUBUKLINGGAU SUMATERA SELATAN)
Authors: Susanto Yohanes , Hendrik Hendrik
Published: March 2021

This study aims to examine the effect of leadership, motivation and compensation on employee performance at the local tax and retribution management body in Lubuklinggau City, with a sample of 38 respondents from employees. shows, partially there is a positive and significant influence of each exogenous variable on the endogenous variables, namely the variables of leadership, motivation and compensation have an effect on employee performance, and simultaneously the four exogenous variables jointly affect employee performance. However, partially the compensation variable is more dominant in influencing employee performance. Management implication, that either simultaneously or partially each variable affects employee performance, however the most dominant variable compensation is therefore it is suggested that management pay attention to the compensation structure in order to improve performance.
Geomechanics substantiation of pillars development parameters in case of combined mining the contiguous steep ore bodies
Authors: Takhanov Daulet , Muratuly Berikbol , Rashid Zhuldyz , Kydrashov Adilzhan
Published: March 2021

Purpose. Determining the actual dimensions of the protecting and crown pillars of ore bodies by seismic survey and assessing the possibility of rock mass collapse and fracturing at the lower levels of the Zhairemskoye field. Methods. An integrated approach is used, which involves the analysis of complete ore bodies development during the combined mining. To determine the geological strength index (GSI) and rock mass rating (RMR), the mass structure is studied, as well as the survey is executed of rock fracturing on the contours of mine workings at levels of +288, +240, +192, +144 m. In addition, the physical and mechanical properties of rocks are refined using the RocLab software. Using the numerical modelling of the self-caving process, when mining the protecting and crown pillars, the processed results of numerical modelling are analysed and the possible zones of the mass deformation are assessed based on the Phase2 software. Findings. It has been determined that during the mining of ore bodies 4 and 6, protecting pillars between the quarry and the underground mine, crown pillars between the levels up to the level of +144 m, the rock displacements are possible along glide surfaces. It has been revealed that the haulage workings of levels +240 and +192 m fall into the zone of possible displacements influence, and the rock pillar between ore bodies 4 and 6 will be exposed to inelastic deformations during the mining of crown pillars to the level of +144 m. It has been found that after the crown pillar development between the levels of +240 and +192 m for ore body 6, the rock pillar destructions are possible between ore bodies 4 and 6, since during the modelling, displacements of more than 2 mm are observed. In this case, the destruction processes are possible in the rock pillar upper part. Originality.A geomechanical assessment of the rocks tendency to caving is given and problem areas of stability during the mining of ore bodies 4 and 6 in the Zhairemskoye field are identified. Practical implications. The stable parameters of protecting and crown pillars have been substantiated, which is an important aspect in the design/efficient technology of mining the contiguous ore bodies. Keywords: engineering seismic, ore body, pillar, level, iron, manganese
Determination of the efficacy of azithromycin on biofilm-forming uropathogenic Escherichia coli isolated from urinary tract infection samples
Authors: Ahsan Sunjukta , Alam Nur E , Sirajee Ahmed Salman
Published: March 2021

The ability of E. coli to form complex surface-associated communities, called biofilms, contribute to its resistance and persistence in Urinary Tract Infection (UTI). In the present study, the ability of uropathogenic E. coli (n=30) isolated from UTI patients to form biofilm and the concentration of Azithromycin to inhibit or kill planktonic and biofilm phase bacteria were investigated. Effects of sub-Minimum Inhibitory Concentration (MIC) of Azithromycin on biofilm formation was investigated. An attempt was also taken to identify the quorum sensing molecule released by E. coli in biofilm. Among the 30 isolates, 6 (20%) were very strong, 8 (26.67%) were strong, 13 (43.33%) were moderate and 3 (10%) were weak biofilm producers. MIC and MBC (Minimum bactericidal concentration) of planktonic phase bacteria were determined and compared with MRC (Minimum regrowth concentration) and MBEC (Minimum biofilm eradication concentration) of biofilm population. MIC values ranged between 0.5 μg/ml to greater than 512 μg/ml. MBC values were measured for ten isolates and the range found was between 8-64 μg/ml. It was found that MRC values were 2-256 times greater than MIC values and MBEC values were 16-256 times greater than corresponding MBC values. After subjecting sub MIC Azithromycin levels to 10 selected isolates, 6 lost the ability to form curli fimbriae and 2 lost their capability of motility in planktonic stage, but none of this ability was lost in biofilm stage. Viable cell count of planktonic cells incubated in sub MIC Azithromycin concentration showed significant decrease of cell number whereas the number of planktonic cells without antibiotic increased significantly. In contrast, for biofilm forming cells, no change in cell number was seen with progressing time for either the presence or absence of antibiotic indicating that biofilm formation could not be inhibited by sub MIC concentrations of Azithromycin. It can be implied that Azithromycin is not the proper drug of choice for eradication of biofilm formed by E. coli. The present study failed to identify the quorum sensing molecule released by the test isolates by the method employed.

Dhaka Univ. J. Biol. Sci. 30(1): 1-11, 2021 (January)
Relationship among islamic dress, religious values and altruistic behavior
Authors: Khanam Mahfuza
Published: March 2021

The present study explored the relationship among Islamic dress, religious values and altruistic behavior. For the study, a total of 120 individuals (60 males and 60 females) were taken by purposive and convenient sampling method. The age of the participants was ranged from 18 to 26 years. To measure altruistic behavior, a pile of loose papers, some books, eraser, etc. and to measure the religious values of the participants, the Allport-Vernon-Lidzey Value Scale were applied on participants selected from different categories. Results showed that dress is significantly correlated with religious values and altruistic behavior. Significant differences have been found in both religious values and altruistic behavior between the participants wearing secular dress and Islamic dress and between male and female respondents. Significant interaction effect also has been found between dress and gender. Result revealed that the participants wearing Islamic dress have more religious values (M =37.31, SD = 6.89) and they show greater altruistic behavior (M = 5.48, SD =1.64) than those wear Secular dress (M =34.41, SD = 6.64 and M = 4.15, SD = 1.54) respectively. In terms of gender difference, it has been found that boys reported significantly less religious values (t = -2.14, p < .01) and greater altruistic behavior (t = 4.59, p <0.05) in comparison to girls.

Dhaka Univ. J. Biol. Sci. 30(1): 13-21, 2021 (January)
Effects of organic manures on the growth and yield of malabar nut (Justicia adhatoda L.)
Authors: Rahman S , Nishi KN , Muslim M , Rahman MK
Published: March 2021

A pot (7 kg soil/pot) experiment was carried out to evaluate the growth performance of malabar nut (Justicia adhatoda L.) as influenced by different organic manures. Manures were (a) ACI, (b) FDA, (c) GTS, (d) Green life, (e) Kaji, (f) Majim, (g) Shebok, (h) Shufola, (i) Cowdung, and (j) Water hyacinth, applied at the rate of 10 ton/ha. There were eleven treatments and three replications. Pots were arranged in a completely randomized design (CRD). To evaluate the growth performance viz. height, leaf number, leaf area, and leaf area index, girth, and branches were recorded at 15 d intervals up to harvest. Plants (90 d old) were harvested as root, stem, and leaf. Fresh and dry weights of root, stem, and leaf were recorded. The highest height (80.90 cm), leaf number (28.70 no./plant), leaf area (175.77cm2/plant), leaf area index (0.462) were observed in water hyacinth. The lowest height (42.20 cm), leaf number (13.70 no./plant), leaf area (45.58 cm2/plant), and leaf area index (0.12) were recorded in control. Maximum fresh and dry weights (root, stem, and leaf) were 129.19 g/plant and 57.97 g/plant found in water hyacinth, respectively. Results concluded that the overall growth and yield were achieved better in water hyacinth manure.

Dhaka Univ. J. Biol. Sci. 30(1): 79-86, 2021 (January)
Regulatory elements in the upstream region of metallothionein gene in tilapia species
Authors: Alam Mohammad Shamimul , Jahan Israt , Rahman Sadniman , Jahan Hawa , Fatema Kaniz
Published: March 2021

Tilapia is a hardy fish which can survive in water bodies polluted with heavy metals. Metal resistance is conferred by higher expression of metallothionein gene (mt) in many organisms. Level, time and tissue-specificity of gene expression is regulated through transcription factor binding sites (TFBS) which may be present in the upstream, downstream, or even in the introns of a gene. So, as a candidate regulatory region, the 5’upstream sequence of mt gene in three tilapia species, Oreochromis aureus, O. niloticus and O. mossambicus was studied. The targeted region was PCR-amplified and then sequenced using a pair of custom-designed primer. A total of only 2.7% variation was found in the sequenced genomic region among the three species. Metal-related TFBS were predicted from these sequences. A total of twenty eight TFBS were found in O. aureus and twenty nine in O. mossambicus and O. niloticus. The number of metalrelated TFBS predicted in the targeted sequence was significantly higher compared to that found in randomly selected other genomic regions of same size from O. niloticus genome. Thus, the results suggest the presence of putative regulatory elements in the targeted upstream region which might have important role in the regulation of mt gene function.

Dhaka Univ. J. Biol. Sci. 30(1): 95-103, 2021 (January)
Correlation of Duration of Hair Loss with Trace Element Level in Hair Loss Patients
Authors: Rahman Farhana , Akhter Qazi Shamima , Yeasmin Nahid , Sultana Farhana , Tabassum Sabira , Habib Tamanna Binte , Akter Tahmina , Akter Sunjida , Seraj Zulfiquar , Khan Md Fardous
Published: March 2021

Background: Hair loss is a worldwide problem with significant prevalence in the developed countries. Although many pathophysiological factors have been involved in the development of hair loss, its etiology is still unclear. Trace elements.

Objective: To assess duration of hair loss with serum iron level in alopecia.

Methods: This cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during January 2017 to December 2017. Serum iron level was estimated by flame atomic absorption spectrophotometry of thirty five newly diagnosed hair loss patients aged 18 to 45 years were study group and thirty five ages, sex and BMI matched healthy subjects were control group. Both male and female was assessed by analyzing time. In this study, the duration of hair loss was 1 to 18 months. Duration of hair loss in study group was divided in two groups such as ≤2 months and >2 months. Patients were selected from Department of Dermatology and Venerology, Dhaka Medical College Hospital, Dhaka. For statistical analysis Unpaired Student’s‘t’ test, Chi square tests and Pearson’s correlation coefficient (r) tests were performed.

Results: In this study, serum iron level showed negative correlation with the duration of disease in study group.

Conclusions: From this study, it is concluded that serum iron deficiency is associated with duration of hair loss patients.

J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 29-32
Effect of Chemotherapy on Liver Function During Induction of Remission in Children with Acute Lymphoblastic Leukemia Receiving Standard Protocol
Authors: Jannat Meftahul , Morshed AKM Amirul , Anwer Sayeeda , Islam Shahnoor
Published: March 2021

Objective: The present study was undertaken to assess liver function (using markers like SGPT, serum bilirubin, prothrombin time, serum albumin) in children suffering from Acute Lymphoblastic Leukemia.

Materials & Methods: This study was carried out in the Department of Pediatric Hematology & Oncology, Dhaka Medical College Hospital, Dhaka, over a period 12 months from the day of approval of the protocol. All acute lymphoblastic leukaemia children admitted in Pediatric Hematology & Oncology Department in Dhaka Medical College Hospital and receiving chemotherapy of standard protocol for induction of remission were the study population. A total of outcome variable was hepatotoxicity resulting from chemotherapy given for induction of remission.

Result: The mean age of the children was 4.4 years (range 2- 8 years). Males were a bit higher in the series with male to female ratio being 11:9. Liver function tests before therapy revealed that none of the children exhibited raised serum billirubin and only 2(4.5%) children had increased SGPT. However, 50% of the children had raised prothrombin and 43.2% had reduced serum . albumin. Liver function tests after therapy after induction of remission shows that 9(20.5%) children exhibited raised serum billirubin, the proportion of children with raised prothrombin remained almost same as before but the status of serum billirubin improved to some extent. However, proportion of children with raised SGPT was increased to 25%. Comparison of liver function in children after therapy during induction of remission with that before induction did not show any significant difference, except that the serum SGPT was significantly raised during induction of remission (p < 0.001).

Conclusion: The study concluded that the current therapy for induction of remission of ALL cases does not produce any toxic effect on liver. Although, enzymes like SGPT take a sharp rise during induction of remission, it is transient and does produce any deleterious effect on liver.

J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 33-37
Mediating Role of Organizational Commitment: A Study of NADRA, Multan Region
Authors: Kashmiri Tanveer , Mehran Malik Muhammad , Hussain Nazar , Pasha Ahmad Tisman
Published: March 2021

The purpose of this study is to investigate how employee compensation and job satisfaction influence employee performance. And more importantly, this study examines the mediating effect of the organizational commitment between employee compensation, job satisfaction and employee performance. Based on the prior studies conducted on employee compensation, job satisfaction, employee performance and organizational commitment, an integrated conceptual framework on employee compensation, job satisfaction, employee performance and organizational commitment was developed. The convenience sampling technique was employed in this study, and a sample drawn was consisted of 375 NADRA employees serving in Multan region. The sample was focused on the employees working in the NADRA Multan region. For more robust testing of the theory organizational commitment was included as mediating variable. For testing of mediation effect Process by Andrew F. Hayes was used with the assistance of SPSS version 23. Research findings revealed that the impacts of employee compensation and job satisfaction on employee performance are positive and significant. And organizational commitment as a mediating variable mediates the relationships between employee compensation, job satisfaction and employee performance. The mindsets of the today employees are changing, and they are more conscious about their relationships with the organizations, they love to share their good and bad experiences with the organizations. Today, it is very important for organizations to know the feelings of the employees about their organizations. This study suggests the organizations by tuning employee compensation, job satisfaction variables they may impact on the performance of the employees. And by introducing organizational commitment they may also change the relationships between employees and organization. Variables part of this study were not old constructs, but it is new for the graphical location where I conducted this study because there was no similar study available here. This study is only focused on NADRA Multan region, other geographical locations or industries may be used to more clearly understand the brand evangelism construct. Also, comparative studies can be performed for different organizational ladders and geographical locations.
A PSICODINÂMICA DO SOFRIMENTO, DO PRAZER E DO TRABALHO
Authors:   UEMG - Universidade do Estado de Minas Gerais - Unidade Frutal, FIGUEIREDO Mari Lúcia , ÁVILA Lazslo Antonio ,   FAMERP - Faculdade de Medicina de São José do Rio Preto
Published: March 2021

The present investigation focuses on the idea that work can be both in the area of health and pathology, both in suffering and pleasure, being always displayed with a double role: work can be structured as it can also happen, it can cause dignity but it can also deteriorate and be alienating. This study aims to present the integration of body and mind and the search for knowledge about the causes of illness and the ways of healing. As a research methodology, we combine the technique of bibliographic review with the psychodynamics of work, which is characterized by the analysis of the psychic processes mobilized by the encounter between the subject and the impositions generated by the organization of work. We have a powerful reference for this reference to psychoanalysis. As a result of this study, it contributes to the analytical listening of suffering and to the construction and strengthening of knowledge, the causes of symptoms and the ways of healing.
An In Vitro Analysis of the Antifungal Effect of Nystatin and Fluconazole Incorporated into Tissue Conditioner with and Without Using Varnish Containing Self-cured Resin and 1,1,1-Trichloroethane
Authors: Ghasemi Shima , Raeesi Safa , Sadr Katayoun , Kiafar Azra , Babaloo Amir Reza
Published: March 2021

Background: Incorporating antifungal drugs into liners has been proposed to treat denture stomatitis. Varnish application on tissue conditioners can decrease the porosities and irregularities, biofilm, and pathogens adhesion. In this study, we evaluated the effect of varnish application on releasing the antifungal drugs incorporated into tissue conditioners. Methods: Pure form of nystatin and fluconazole were mixed into tissue conditioner powder separately at 5% wt/wt concentration and prepared according to manufacturer’s instruction. Then, disk-shaped specimens (5 mm in diameter and 1 mm in thickness) were prepared at 30 nystatin and 30 fluconazole specimens. Varnish (containing 50 mL of 1,1,1-trichloroethane and 3 ml of self-cured resin) was applied on the surface of 15 disks of each drug and the other specimens were used as the control group (without varnish). Next, the disks were put in agar plates cultured with standard Candida albicans and incubated for 7 days. Mean inhibition diameter for each disk was measured with digital caliper at 24 hours, 3 days, and 7 days. Each step was performed in triplicate. Data was analyzed with one-way ANOVA and Friedman, Wilcoxon, and Mann-Whitney U tests. Results: The mean inhibition diameter (MID) at days 1, 3, and 7 in fluconazole without varnish group was 12.63, 3.90, and 3.67, respectively; in fluconazole with varnish was 3.00, 2.50, and 2.50, respectively; in nystatin without varnish was 5.78, 3.90, and 3.87, respectively; in nystatin with varnish group was 2.50, 0.00, and 0.00, respectively. fluconazole without varnish group exhibited significantly higher MID and nystatin with varnish group had lower MID. Conclusions: In this experimental study, fluconazole was more effective than nystatin. In groups without varnish, antifungal effect continued up to day 7. Using varnish in tissue conditioner can decrease antifungal effect.
The Role of PGC1-1a in Modulating Oxidative Stress, Cardiovascular Risk Factors, and Cellular Metabolism in Cardiomyocytes
Authors: Ahmadi Ali
Published: March 2021

1
Somatic Mutations in Exons 10, 11, and 16 of the RET Protooncogene in Medullary Thyroid Carcinoma Patients
Authors: Shakiba Elham , Hedayati Mehdi , Majd Ahmad , Movahedi Monireh
Published: March 2021

Introduction: Medullary thyroid carcinoma (MTC) comprises nearly 5% of all cases of thyroid cancer (TC). Aberrant activation of RET (rearranged during transfection) signaling via somatic mutations is the basic molecular mechanism of MTC tumorigenicity. In this study, we determined the incidence of RET gene mutations in exons 10, 11, and 16 in Iranian patients. Methods: A total of 33 patients undergoing thyroidectomy at Imam Khomeini hospital of Tehran, Iran and diagnosed with MTC were enrolled. For investigating mutations in exons 10, 11, and 16, DNA was extracted from tumor tissues, and the genes were amplified by polymerase chain reaction (PCR) and then sequenced. Results: Out of 33 patients, 20 (60.6%) subjects had mutations in one of the examined exons (10, 11, and 16). According to our results, the "ATG918ACG" mutation in codon 918 had the highest rate. Conclusion: Testing RET mutations can be beneficial in clinical evaluation and treatment management of MTC patients.
Phylogenetic Study of VP6 Gene of Bovine Rotavirus A and Molecular Survey of Bovine Rotaviruses B and C, and Human G and P Genotypes of Rotavirus A in Calves in Iran
Authors: Nazaktabar Ahmad , Madadgar Omid
Published: March 2021

Background: Rotavirus (RV) is one of the most important causes of diarrhea in the calf and human neonates. Rotaviruses are divided into nine different serogroups, of which group A is more important compared to other groups. Objective: This study was performed because of the lack of information about the importance and prevalence of bovine rotaviruses B (RVB) and C (RVC) and human genotypes of rotavirus A (RVA) in the bovine population in Iran. Phylogenetic analysis of VP6 of bovine RVA was the second aim of the present study. Materials and Methods: A total of 581 stool specimens were collected from diarrheic calves of 14 provinces and were analyzed by reverse transcription polymerase chain reaction (RT-PCR) and 485 of them were investigated by PAGE electrophoresis to determine the frequency of three rotaviruses A (RVA), B (RVB), and C (RVC). The presence of human G and P genotypes in Iranian bovine population was also evaluated using semi-nested multiplex RT-PCR. Results: RVA was detected by RT-PCR (VP6 gene detection) in 16.2% (94/581) and by PAGE in 22.16% (108/485) and no positive cases of RVB and RVC were confirmed by polyacrylamide gel electrophoresis (PAGE). This study showed that non-A RV groups (B and C) have little role in calf diarrhea in Iran. The results of the phylogenetic study of VP6 sequences of rotaviruses A identified in this study showed that they all belonged to genotype I2 and were classified into three different branches. Specimen isolated in Zanjan showed the highest difference (maximum identity of 94%) with other sequences and clustered along with the Japanese strain, R22. Human G and P genotypes were not found in the studied samples. Conclusion: The results showed that non-A rotaviruses and human genotypes of RVA are of little importance in calf rotavirus diarrhea in Iran. Also, there is the first phylogenetic study of rotavirus A VP6 protein in Iran.
Planejamento urbano no município de Juazeiro do Norte, Ceará: concepções de desenvolvimento urbano em questão
Authors: Van den Brule David Melo
Published: March 2021

É possível perceber dois ideais em torno da cidade: a cidade-mercado e a cidade-direito (SANTOS JUNIOR 2007). Partindo dessa perspectiva, o presente trabalho, fruto de nossa tese de doutorado, objetivou identificar como a concepção de desenvolvimento urbano foi abordada no Plano Diretor do município de Juazeiro do Norte-CE (1997-2000), bem como na compreensão de pessoas vinculadas à gestão municipal daquele período, por meio de entrevistas realizadas entre os anos de 2016 a 2019. Quanto aos resultados, vimos que o PDDU (1997-2000) foi marcado por sua aproximação com a ideia de empreendedorismo urbano, especialmente quando se observam as linhas estratégicas traçadas no documento. Já para nossos entrevistados, de modo geral, a ideia do bem-estar aparece como propósito do desenvolvimento urbano, aspecto que vai desde a garantia ao acesso à infraestrutura até a ideia de gerar mais acesso à saúde, educação, moradia, segurança e saneamento.
Strategic Planning of Information Systems for Mosque in Indonesia
Authors: Maulani Galih Abdul Fatah , Sapril Mubarok Teten Mohamad
Published: March 2021

Anticipating the era of Society 5.0, communities and organizations are required to have integrated and comprehensive information access, including the management of mosques in Indonesia. This study aims at providing a strategic planning in the form of a portfolio for future application of mosques management information system services. This study was conducted with reference to Ward and Peppard’s strategic plan for information systems, which included SWOT analysis, critical success factor method and McFarlan’s strategic grid. The results showed the mosque management must have several applications, mapped into 4 quadrants (strategic, high potential, key operation, and support). It is expected that this application portfolio can help managers of mosques in Indonesia provide faster, more accurate, and more accountable information.
J.Co Donuts & Coffee’s Consumer Satisfaction
Authors: Permana Intan
Published: March 2021

This research dicusses customer satisfaction. Researcher will use desriptive design in advance to get insight and understanding about research problem, and then the result from descriptive design will be used as input for conclusive research is 66 respondents. The result of this research shows that customers will be satisfacted to consumption J.Co Donuts, J.Pops Baby Donuts, J.Coffee, J.Cool and J.Club if J.Co Donuts & Coffee offered the good innovation attributes, change behavior, suitability of offering and quality of service.
ANALISA KUALITAS PELAYANAN, KEPERCAYAAN DAN KEAMANAN TERHADAP TINDAKAN PEMBELIAN PRODUK SECARA ONLINE
Authors: Handaruwati Indah
Published: March 2021

This study will examine the Analysis of Service Quality, Trust and Safety of Online Purchasing Actions. The purpose of this research is to find out how far the role of service quality, trust and security will be in online purchasing and to provide an overview of consumer behavior when considering making a purchase. This study uses a questionnaire as a research instrument to obtain data from consumers who make online purchases with a total sample of 30 people. The analysis tool that will be used is Multiple Linear Regression to test the effect of the independent variable on the dependent variable. The results of the multiple linear regression equation are obtained Y = 0.256 0.613+ 0.115+ e Based on the regression equation, the variables of Service Quality, Trust and Safety all have an influence on Online Purchasing Actions. Results of the F-test. From testing using the F test, it was found 76.513. This figure means that the effect of Service Quality, Trust and Security on Online Purchasing Actions is 76,513. Meanwhile, from the results of the t test there is a relationship between service quality factors of 4,657, security of 6,628, and trust of 4,751. Of the three factors, the security factor is the dominant influence.

 Keywords: Quality of service, Trust, Security and Online Purchasing Actions
Democracy, Good Governance, and the Phenomenon of Corruption in Nigeria
Authors: Yakubu J. Ademola
Published: March 2021

Democracy is a concept that has been recognized as an acceptable mode of governance. Embedded in this idea however are different approaches with respect to the attainment of this objective. The faults’ inherent in some of these approaches led to the recognition of ‘good governance’ as a more acceptable concept in the description of the governance concept. Corruption is a negation of the ideals of democracy and good governance. This paper seeks to show how corruption has destroyed the fabric of ‘democracy’ and ‘good governance’ and the pursuit of the fundamental values of freedom, happiness, peace and order in the Nigerian society.
Hubungan Motivasi Belajar, Bimbingan Akademik dengan Prestasi Akademik Mahasiswa Jurusan Pendidikan Bahasa dan Sastra Indonesia, Fakultas Bahasa dan Seni, Universitas Negeri Manado
Authors: Meruntu Oldie Stevie
Published: March 2021

Abstrak. Penelitian ini bertujuan: (1) mengetahui hubungan motivasi belajar dengan prestasi akademik mahasiswa Jurusan Pendidikan Bahasa dan Sastra Indonesia, Fakultas Bahasa dan Seni Universitas Negeri Manado dan (2) mengetahui hubungan antara bimbingan akademik dengan  prestasi  akademik  mahasiswa  Jurusan  Pendidikan  Bahasa  dan  Sastra  Indonesia, Fakultas  Bahasa  dan  Seni  Universitas  Negeri  Manado.  Metode  yang  digunakan  dalam penelitian ini adalah metode kuantitatif dengan jenis rancangan korelasional. Populasi penelitian ini adalah mahasiswa semester III, V, dan VII yang berjumlah 420 orang, sedangkan sampel penelitian berjumlah 41 mahasiswa, yang diambil secara acak dari setiap semester tersebut. Hasil penelitian yang telah dilakukan, menunjukkan: (1) terdapat hubungan yang positif  antara  motivasi  belajar  dengan  prestasi  akademik  mahasiswa  Jurusan  Pendidikan Bahasa dan Sastra Indonesa, Fakultas Bahasa dan Seni, Universitas Negeri Manado. Hasil penelitian menunjukkan bahwa angka korelasi yang diperoleh dari kedua variabel ini sebesar 2,063. Dari hasil pengujian tampak bahwa r hitung 2,063 lebih besar dari r tabel 0,308. Dengan demikian, korelasinya signifikan. (2) Terdapat hubungan yang positif antara bimbingan akademik dengan prestasi akademik mahasiswa Jurusan Pendidikan Bahasa dan Sastra Indonesia, Fakultas Bahasa dan Seni, Universitas Negeri Mamando. Hasil menunjukkan hubungan yang sangat positif antara motivasi belajar dengan prestasi akademik menunjukkan angka 2,27.  Jika dihubungkan dengan r tabel sebesar 0,308, sedangkan r hitung adalah 2,27. Tampak bahwa r hitung lebih besar dari r tabel, sehingga hubungannya signifikan.Kata Kunci: Hubungan, Motivasi Belajar, Bimbingan Akademik, Prestasi Akademik
Pemertahanan Bahasa Tontemboan di Kalangan Pemuda Desa Mokobang Kecamatan Modoinding Kabupaten Minahasa Selatan
Authors: Otay Brenda C. , Pesik Nikolas , Pangemanan Nontje J.
Published: March 2021

Abstrak.  Masalah  yang  dihadapi  bahasa  Tontemboan     Mokobang saat  ini  adalah kuatnya  pengaruh  bahasa  melayu  Manado  (BMM)  sehingga  frekuensi  berbahasa  daerah pemuda   sudah   sangat   menurun   hal   ini   sangat   mempengaruhi   pemertahanan   bahasa Tontemboan dikalangan pemuda. Tujuan penelitian ini ialah untuk mendeskripsikan penggunaan   bahasa   Tontemboan   di   kalangan   pemuda   Desa   Mokobang   Kecamatan Modoinding  Kabupaten  Minahasa  Selatan.  Metode  yang  digunakan  dalam  penelitian  ini adalah metode deskriptif kualitatif. Sumber data penelitian ialah pemuda berusia 15-30 tahun. Untuk mengumpulkan data, teknik yang digunakan adalah teknik simak, teknik cakap, teknik catat serta teknik rekam. Hasil penelitian menunjukkan bahwa BT masih bertahan ketika BT digunakan terhadap orang yang lebih tua dalam situasi baik akrab maupun tidak akrab, juga terhadap oran yang berusia sebaya/lebih muda dan akrab dengan remaja.Kata Kunci:    Pemertahanan, Bahasa Tontemboan, Kalangan Pemuda
Pembelajaran Menulis Teks Editorial Melalui Penerapan Strategi Pemodelan Pada Siswa Kelas XII SMA Negeri 1 Tahuna
Authors: Karimang Non Evelin , Ratu Donal M , Pangemanan Nontje J.
Published: March 2021

Abstrak: Tujuan penelitian ini adalah:  1) menggambarkan penerapan strategi pemodelan dalam pembelajaran menulis teks editorial pada  siswa kelas X SMA Negeri 1 Tahuna dan 2)  menggambarkan kemampuan menulis teks editorial siswa kelas XII SMA Negeri 1 Tahuna melalui penerapan strategi pemodelan.Metode yang digunakan dalam penelitian ini adalah metode deskriptif analitik. Sumber data penelitian adalah siswa kelas XII IPSa, yang berjumlah 23 orang. Teknik penelitian menggunakan pengamatan dan tes. Cara analisis data memadukan cara analisis deskriptif dan kuantitatif .    Hasil  penelitian menunjukkan: 1)  penggunaan strategi pemodelan dalam menulis teks editorial memberikan kesempatan yang begitu besar kepada siswa terlibat secara aktif dalam pembelajaran menulis. Penggunaan strategi pemodelan yang digunakan dalam pembelajaran menulis teks editorial pada siswa kelas XIIA SMA Negeri 1 Tahuna memfokuskan kegiatan siswa pada menelaah dan menulis teks editorial. 2) Kemampuan siswa menulis teks editorial dengan strategi pemodelan adalah 81.71% atau berada pada kategori mampu. Nilai rata-rata siswa secara klasikal yang dicapai siswa melampaui Kriteria Ketuntasan Minimal (KKM) yang ditentukan guru bahasa Indonesia di kelas XII SMA Negeri 1 Tahuna, yakni 78%, maka nilai rata-rata yang dicapai oleh siswa ini secara klasikal melampaui ketuntasan minimal. Kata Kunci: Pembelajaran, Menulis, Strategi Pemodelan
Alih Kode Guru dalam Pembelajaran Bahasa Indonesia Kelas VIII A SMP Negeri I Remboken
Authors: Mamahit Yossy Jonathan , Palar Wimsje Revlin , Meruntu Oldie Stevie
Published: March 2021

Abstrak. Bahasa Indonesia merupakan bahasa pengantar di dalam kegiatan belajar-mengajar di kelas. Namun, dalam penggunaannya di kelas, guru masih saja beralih kode. Tujuan penelitian ini ialah untuk mendeskripsikan alih kode yang terjadi dalam penggunaan bahasa Indonesia guru dalam interaksi belajar mengajar serta untuk mengejar faktor penyebab terjadinya alih kode. Metode yang digunakan dalam penelitian ini ialah metode kualitatif. Untuk megumpulkan data, teknik yang digunakan ialah observasi dan rekam. Untuk menganalisis data, teknik yang digunakan ialah transkrip data rekaman reduksi data. Sumber data penelitian ialah guru bidang studi bahasa Indonesia. Hasil penelitian menunjukan bahwa bentuk-bentuk alih kode yakni alih kode bentuk kalimat, alih kode antar kalimat dan alih kode intra kalimat muncul dalam pembelajaran dalam kelas oleh guru. (1) Alih Kode yang terjadi dalam penggunaan bahasa Indonesia oleh guru di kelas adalah alih kode bahasa melayu Manado (BMM); (2) Bahasa Indonesia yang digunakan adalah Bahasa Indonesia Baku (BIB) yang bercampur kode dengan BMM bahkan campur kode antara BIB, BII, dan BMM; (3) Alih kode terjadi pada konteks yang berkaitan dengan kehidupan siswa. Selain itu, faktor penyebab alih kode juga terbukti mempengaruhi guru sehingga muncullah alih kode dalam kegiatan belajar mengajar dalam kelas.Kata Kunci: : Alih Kode, Pembelajaran, Bahasa Indonesia
Makna Spiritual dan Unsur Stilistika dalam Mantra Ngeroras Adat Hindu Bali di Desa Werdhi Agung
Authors: Suwija Dessy Najenia , Katuuk Kamajaya Al , Rotty Viktory Nicodemus Joufree
Published: March 2021

Penelitian ini bertujuan untuk mengungkapkan makna Spiritual dan Unsur Stilistika yang terdapat dalam mantra Ngeroras. Metode yang digunakan yakni metode deskriptif kualitatif dan dengan teknik pengumpulan data observasi dan wawancara, sedangkan dengan teknik analisis data berupa pengumpulan data, reduksi data, penyajian data, verivikasi dan penegasan kesimpulan. Berdasarkan analisis data didapatkan bahwa, makna spiritual yang ada dalam upacara negeroras meliputi : 1) makna dari mantra Amet Toya Hening (mengambil air jernih) adalah diharapkan dengan air yang disiramkan ke tempat atma atau roh yang dingeroras akaan bersih dan suci. 2) makna spiritual dari Mapinton atau Mapajati diharapkan apabila upacara ngeroras di laksanakan dapat berlangsung dengan baik dan roh leluhur yang dingeroras mendapatkan kedamain, kebebasan, ketenang, dan kesempurnaan. 3) makna spiritual dari ngilenin padudusan diharapkan dewa surya yang agung dengan kilauan yang merah dapat hadir dalam acara ngeroras dan memberi kesemarakan kedalam acara ngeroras tersebut. 4) makna spiritual dari pitra puja diharapkan atma atau roh leluhur dapat mencapai surga akhirat tanpa penderitaan. 5) makna spiritual dari pitra puja diharapkan atma suci mendapatkan tempat di Moksa dan tak terlahir kembali atau mendapat keabadian di akhirat tanpa ada siksaan. 6) makna spiritual dari pitra puja diharapkan atma suci mendapatkan ketenangan yang abadi. 7) makna spiritual pitra puja diharapkan atma suci mendapatkan kebahagian abadi di akhirat. 8) makna spiritual pitra puja diharapkan atma suci mendapatkan pengampunan dari hyang widhi. 9) makna spiritual pralina maknanya agar atma suci mencapai moksa dan menyatu dengan ida sang hyang widhi wase dan tanpa suka duka. 10) makna spiritual nganyud sekah diharapkan atma setelah kematian akan tetap mengingan menyebut om dan ingat kepada ida sang hyang widhi wase dengan kekuatan dan keabadiannya serta mengingan bahwa karma phala selalu mengikuti hingga di akhirat nanti. Sedangkan unsur stilistika dalam mantra ngeroras yaitu: repitisi, tautotes, asonansi, aliterasi, hiperbola, pararima, dan anaphora.
Korelasi Kompetensi Pedagogik Guru PAI dengan Motivasi Belajar Peserta Didik Di Sekolah Inklusi
Authors: Suliwati Suliwati
Published: March 2021

This study aims to determine whether there is a correlation between the pedagogical competence of Islamic Education Teachers and the learning motivation of students in Islamic Education subjects in inclusive schools at SMP IT Nidaul Hikmah, Salatiga in the academic year 2018/2019. The subjects in this study were 62 students of class VII B and VIII B including students with special needs with disabilities and learning difficulties (slow learner). This approach of research is a quantitative correlation. The method used to obtain data or information by using a questionnaire or questionnaire sheet. The analysis used in this research is using descriptive analysis and the product-moment correlation hypothesis testing which is assisted by the application program SPSS version 25.00. The results of this study showed that the pedagogical competence of Islamic Education teachers in the very low category was 3.2%, the low category was 27.9%, the moderate category was 48.4% and the high category was 20.9%. The learning motivation of students in the Islamic Education subject in the very low category was 27.4%, the low category was 27.4%, the moderate category was 33.9% and the high category was 11.3%. The correlation between Islamic Education teacher pedagogical competence and learning motivation in the Islamic Education subjects based on the calculation of the correlation stated that the null hypothesis (Ho) was rejected and the alternative hypothesis (Ha) was accepted with the value of > r table with 0.495 > 0.244. Indicated that the correlation between the Islamic Education teacher pedagogical competence and students learning motivation in Islamic Education subjects has a positive moderate category and significant correlation.
Pengaruh Penerapan Standar Komunikasi Defisit Perawatan Diri terhadap Kemandirian Merawat Diri pada Pasien Skizofrenia di Ruang Rawat Inap Delta Rumah Sakit Jiwa Daerah Provinsi Jambi
Authors: W Rd Hari Periza , Yanti Rahmi Dwi , Putri Vevi Suryenti
Published: March 2021

Schizophrenic is a disease that affects the brain and causes strange, disturbed thought, perception, emotion, movement, and behavior. These case made patient experiencing significant self-care deficit, causing patients did not pay attention to hygiene. The nursing tread to deal the patient with schizophrenic is the application of self-care deficit communication standard. This study aimed to indicated the influence of applying self-care deficit communication strategies to self-care independence in schizophrenic patient. This study used quantitative research by using pre pre-experiment design, with one group pretest posttest was used. The number of samples were 20 persons. This study used purposive sampling technique. It was conducted on January 1th - 15th 2020. The data were collected by an instrument in the form of observation sheets. It were analyzed by the Wilcoxon test. The findings, The average self-care independence before implementing the self-care communication deficit standard with an average value (3.00) to (4.00) after the application of communication standards is given. There is a difference in the application of the self-care deficit communication standard with a P-value = 0.001