bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural and dielectric properties of Ba0.95Bi0.05Ti1-xFexO3ceramics at x=0.0, 0.1 and 0.2 prepared by solid state method
Authors: Gouitaa Najwa , Lamcharfi Taj-dine , Bouayad Lamfadal , Abdi Farid , Naciri Bennani Mohammed
Published: November 2019

The Ba0.95Bi0.05Ti1-xFexO3 ceramics at (x=0.0, 0.1 and 0.2) were prepared by the solid-state reaction method. The effect of iron substitution on structural and dielectric properties of Ba0.95Bi0.05TiO3 ceramic was studied. These compounds are found to crystallize in only tetragonal phase for x = 0.0 and 0.1 and the mixture of tetragonal and hexagonal phases for x = 0.2. The dielectric properties of Ba0.95Bi0.05Ti1-xFexO3 ceramics at x=0.0, 0.1 and 0.2 of Fe -doping concentration. The dielectric measurements as a function of temperature and frequency are studied and showed two diffuse phase transition and relaxation phenomena. The evolution of dielectric permittivity as a function of the frequency of undoped Ba0.95Bi0.05TiO3 show a relaxation phenomenon for which is displaced to the higher frequencies accompanied by a decrease in dielectric constant when x increase. The Complex impedance Cole-Cole plots showed a negative temperature coefficient of resistivity (NTCR) behavior of the Ba0.95Bi0.05Ti1-xFexO3 materials and increased in grain and grain boundaries resistivity. The relaxation behavior in the test materials is found to be of non-Debye type.
Effect of barium doping on electrical and electromechanical properties of (1-x)(Na0.5Bi0.5)TiO3-xBaTiO3
Authors: Mesrar Mohammed , Lamcharfi Tajdine , Echatoui Nor-Said , Abdi Farid , Ahjyaje Fatima Zahra , Haddad Mustapha
Published: November 2019

The influences of calcination temperature and doping with cobalt in A–site on structural and dielectric properties of CaCu3-xCoxTi4O12 (CCCxTO, x = 0.00, 0.02 and 0.10) ceramics sintered at 1050 0C for 8h were investigated. The ceramic samples are prepared by the conventional solid-state method using high purity oxide powders, and they are calcined at 850 °C, 950 °C and 1050 0C for 4h. The X-ray diffraction (XRD) analysis of pure and doped CCTO samples calcined at 950 °C and 1050 0C showed no traces of any other secondary phases, while impurity phases alongside CCTO phase in the x=0.00 sample calcined at 850 0C was observed. Scanning electron microscopy (SEM) investigation showed an increase in grain size with increasing of Co content and calcining temperature. Dielectric measurements indicated that the dielectric constant of the pure CCTO calcined at 1050 0C/4h has a low value in the frequency range of 1kHz up to 1MHz, whereas the substitution of Co up to x = 0.10 into CCTO caused a huge increase in the dielectric constant value of the calcined samples which is equal to 153419 and 18957 at 950 °C and 1050 0C respectively. The complex impedance analysis of all samples shows a decrease in resistance with an increasing temperature, which suggests a semiconductor nature of the samples
Monoclinic Li2TiO3 Nano-particles via sol-gel method: Structure and impedance spectroscopy
Authors: Krimech Fatima Zahra , Sayouri Salaheddine , Lamcharfi Taj-Edine , Ahjyaje Fatima Zahra
Published: November 2019

Pure phase Li2TiO3 nano-particles were synthesized by the sol-gel method, and the structural properties were examined with X-ray diffraction (XRD) technique. The latter showed that these materials, heat treated at relatively low temperature 900°C during 4h compared to the conventional solid-state reaction which calcination temperature is about 900–1100°C for 10 h; crystallize in the monoclinic phase without the presence of secondary phases. The microstructure of the LT ceramic (sintered at 1100°C) were determined by SEM, and good crystalline nature was observed with an average of granular size 2 μm. Moreover, the impedance spectroscopy showed at a higher temperature of 500°C the low-frequency arc due either to the grain boundary or sample-electrode charge transport processes.
Study of structural and dielectric properties of Nickel-doped BaTiO3 material
Authors: Ed-Dnoub Hafes , El Ghadraoui Ouafae , Zouhairi Mohammed , Harrach Ahmed , Lamcharfi Tajeddine , El Ghadraoui El Houssine
Published: November 2019

In this work, the effect of nickel (Ni) insertion on the structural and dielectric properties of BaTiO3 material was investigated. A series of powders of composition Ba1-xNixTiO3 (x = 0, 0.05, 0.1, 0.15 and 0.20) were synthesized by solid method. The analysis by X-Ray Diffraction (XRD) shows that the obtained compounds crystallize in a phase of perovskite type. All the peaks are indexed in a phase of quadratic symmetry. Characterization by the Scanning Electron Microscope (SEM) indicates a heterogeneous microstructure of the grains. The study by spectroscopy of impedance in the frequency range [500Hz-1MHz] highlighted the effect of the nickel insertion on the transition temperature and the dielectric constant value.
The effects of calcination and doping on structural and dielectric properties of CaCu3-xCoxTi4O12 ceramic
Authors: Hadi Nasr , Lamcharfi Tajdine , Abdi Farid , Echtoui Nor-Said , Harrach Ahmed , Zouhairi Mohammed , Ahjyaje Fatima Zahra
Published: November 2019

The influences of calcination temperature and doping with cobalt in Aâ€“site on structural and dielectric properties of CaCu3-xCoxTi4O12 (CCCxTO, x = 0.00, 0.02 and 0.10) ceramics sintered at 1050 0C for 8h were investigated. The ceramic samples are prepared by the conventional solid-state method using high purity oxide powders, and they are calcined at 850 Â°C, 950 Â°C and 1050 0C for 4h. The X-ray diffraction (XRD) analysis of pure and doped CCTO samples calcined at 950 Â°C and 1050 0C showed no traces of any other secondary phases, while impurity phases alongside CCTO phase in the x=0.00 sample calcined at 850 0C was observed. Scanning electron microscopy (SEM) investigation showed an increase in grain size with increasing of Co content and calcining temperature. Dielectric measurements indicated that the dielectric constant of the pure CCTO calcined at 1050 0C/4h has a low value in the frequency range of 1kHz up to 1MHz, whereas the substitution of Co up to x = 0.10 into CCTO caused a huge increase in the dielectric constant value of the calcined samples which is equal to 153419 and 18957 at 950 Â°C and 1050 0C respectively. The complex impedance analysis of all samples shows a decrease in resistance with an increasing temperature, which suggests a semiconductor nature of the samples.
The commissioner’s perspective: the lived realities of commissioning children’s preventative services in England and the role of discretion
Authors: Body Alison
Published: November 2019

Commissioning remains the dominant process by which England’s state and third sector financial relationships are managed, attracting much criticism and debate. In response, the Civil Society Strategy (HM Government 2018) has called for a renewed focus on collaborative commissioning
arrangements. However, the absence of much comment on commissioners suggests we have not paid enough attention to the role of the individuals who manage these processes. Semi-structured interviews with 15 commissioners, responsible for children’s preventative services, provide new empirical
evidence exploring commissioners’ lived experiences. Drawing on the notion of vertical discretion, which is an individual’s freedom from external control, versus horizontal discretion, which is an individual’s freedom for decision making, this article explores the space for
commissioners’ individual discretion within the commissioning process. Findings highlight that greater consideration of the role discretion has in commissioning processes can add some insight into how more collaborative commissioning arrangements may be achieved at a local level.
Reel by reel: Jan Stanislav Kolár’s narrative poetics in the context of transition to feature-length format in Czech silent cinema
Authors: Kos Martin
Published: November 2019

This article examines the screenwriting practice in Czech silent cinema in the late 1910s and 1920s. It focuses on Jan Stanislav Kolár’s narrative poetics as a case study of specific storytelling choices within the transitional era from one- or two-reelers to the feature-length format in the context of local technological restrictions in exhibition – inevitable breaks of changing film reels in single-projector cinemas. Poetological analysis of Kolár’s Řina (1926) with his other surviving scenarios and pictures shows that meant not only the necessity of adapting to these limitations, but also became a productive way of achieving particular effects on the audience. Semi-independent narrative acts, thrilling moments occurring at the end of the reel, or significant shifts in space and time between two reels were integral parts of his own original stories as well as adaptations of various novels. Nevertheless, the article outlines more general perspective in relation to film reels as structural narrative units and screenwriting practice among Czech filmmakers as well.
Walter Reisch: The musical writer
Authors: Tieber Claus
Published: November 2019

Academy Award-winning Austrian screenwriter Walter Reisch’s (1903–83) career started in Austrian silent cinema and ended in Hollywood. Reisch wrote the screenplays for silent films, many of them based on musical topics (operetta films, biopics of musicians, etc.). He created the so-called Viennese film, a musical subgenre, set in an almost mythological Vienna. In my article I am analysing the characteristics of his writing in which music plays a crucial part. The article details the use of musical devices in his screenplays (his use of music, the influence of musical melodrama, instructions and use of songs and leitmotifs). The article closes with a reading of the final number in the last film he was able to make in Austria: Silhouetten (1936).
Network television writers and the ‘race problems’ of 1968
Authors: Murphy Caryn
Published: November 2019

This article examines the development of television scripts in the crime drama genre within the context of US commercial broadcasting in the network era. In 1968, public discourse around race relations, civil rights and violence reached a height following the assassinations of Martin Luther King, Jr and Robert F. Kennedy, and the release of a government study on urban uprisings by the National Advisory Commission on Civil Disorders. Ironside (1967–75, NBC) and N.Y.P.D. (1967–69, ABC) are two crime dramas that drew on recent events related to black militants and white supremacy in order to appeal to viewers with socially relevant entertainment during this time. The archival records of screenwriters Sy Salkowitz and Lonne Elder make it possible to trace the development of one episode from each series over the course of multiple drafts. This analysis of the script development process explores the relationship between public discourse, industrial context, commercial agendas and creative priorities. Ironside and N.Y.P.D. are both crime dramas, but an examination of both series yields points of divergence which help to illustrate the norms of the network system in terms of act structure, genre tropes, and the oversight of standards and practices.
From dialogue writer to screenwriter: Pier Paolo Pasolini at work for Federico Fellini
Authors: Romanelli Claudia
Published: November 2019

Pier Paolo Pasolini was a poet, novelist, essayist and filmmaker who also worked as a screenwriter for some of the most important Italian directors including Mario Soldati, Mauro Bolognini and Bernardo Bertolucci, to name a few. While Pasolini’s poems, novels and films are widely studied, his work as a screenwriter has not attracted much critical attention. This is partly because Pasolini tended to collaborate with directors whose artistic tastes were very different from his own, making it difficult to understand what he could possibly bring to the films on which he worked. The fact that he took his first steps in the screenwriting teams for which Italian cinema was famous has also contributed to downplay his screenwriting activity. One such example is his contribution to Federico Fellini’s screenplays. Fellini first approached Pasolini because he wished to revise the dialogue in Le notti di Cabiria, which he thought lacked the authentic feel of the language spoken in the Roman slums where the film took place. Although critics have always assumed that Fellini discarded Pasolini’s revisions to his scripts, archival sources tell a different story, revealing Pasolini’s key contribution to Fellini’s work and his eagerness to leave a lasting impression on it.
Molecular and histopathological confirmation of clinically diagnosed lumpy skin disease in cattle, Baghdad Province of Iraq
Authors: Gharban Hasanain A. J. , Al-Shaeli Sattar J. J. , Al-Fattli Hams H. H. , Altaee Muthanna N. K.
Published: November 2019

Aim: This study aimed to confirm the clinically diagnosed cattle with lumpy skin disease (LSD) at Baghdad Province/Iraq from October 2018 to March 2019. Materials and Methods: Molecular polymerase chain reaction (PCR) and histopathology were applied for the detection of LSD among 71 infected cattle issued for slaughter. Results: Pre-slaughter clinical examination showed significant increases (p<0.05) in values of temperature (39.7±0.74°C), pulse (96.42±3.51), and respiratory (33.54±0.63) rates. Enlargement of lymph nodes (prescapular, supramammary, and prefemoral), lacrimation, mucopurulent nasal discharge, salivation, edema in limbs and head among severe infected cases, and marked fall in milk production was seen. An association of LSD to risk factors (age, gender, and areas) showed that there is significant elevation in prevalence of disease in >2-5 years (54.93%) rather than other age groups (>5 and <2 years) in females (73.24%) than males (26.76%); and in sub-rural (42.25%) and rural (39.44%) compared to urban (18.31%) areas. Postmortem examination appeared nodular lesions in upper parts of the digestive system (9.86%), rumen (2.82%), upper respiratory tracts (7.04%), and lung (4.23%). The PCR examination of P32 and thymidine kinase antigenic genes showed 90.14% and 60.56% positive samples, respectively. Histopathological analysis of nodular skin biopsies showed edema, hyperemia, acanthosis, severe hydropic degeneration, and hyperkeratosis in epidermis; whereas, mononuclear cell infiltration, inclusion bodies, and vasculitis seen in the dermis. Conclusion: PCR and histopathology assay could be a potential method to confirm the LSD infection concomitant with clinical examination.
Quantitative evaluation of viral interference among Egyptian isolates of highly pathogenic avian influenza viruses (H5N1 and H5N8) with the lentogenic and velogenic Newcastle disease virus genotype VII in specific pathogen-free embryonated chicken eggs model
Authors: Soliman Mohamed A. , Nour Ahmed A. , Erfan Ahmed M.
Published: November 2019

Background and Aim: Mixed infections of the highly pathogenic avian influenza virus (HPAIV) and Newcastle disease virus (NDV) are considered the most distressing problem of the poultry industry. The problem arises due to the influence of a hidden virus on the replication of another suspected virus. Consequently, misdiagnosis of the real cause of disease may become a source of infection for other healthy stock by transmission and dissemination of the hidden virus. This study aimed to determine the impact of HPAIV and NDV on each other in a specific pathogen-free embryonated chicken egg (SPF-ECE) model. Materials and Methods: HPAIVs (H5N1 and H5N8) and NDVs [avirulent NDV [avNDV] and velogenic NDV [vNDV]) were inoculated into the allantois cavity of SPF-ECE with graded titers (2, 3, and 4 log10 EID50) at 24 and 48 h of incubation, followed by the collection of allantoic fluid. A quantitative reverse transcription real-time polymerase chain reaction was used to determine the viral RNA copies of both viruses. Results: Obvious interference was reported on the growth of NDVs when co-inoculated with AIVs. NDV RNA titers reduction ranged from <3 to 5 log10 to complete suppression, but slight interference with the growth of AIVs occurred. H5N1 RNA titers showed <1-2 log10 reduction when co-inoculated with vNDV compared with the H5N1 control. The interference impact of H5N8 was more powerful than that of H5N1, while vNDV showed more resistance for interference than the avNDV strain. On the other hand, interference of AIVs was not observed except when vNDV was inoculated before H5N1. The interfering impact was increased after 48 h of inoculation, whereas no titer of avNDV was detectable. Conclusion: AIV strains had a powerful effect on NDV growth, regardless of which infection occurred first.
Neuroeducation:An Approach to Brain Plasticity in Learning
Authors: Sousa Léa Barbosa de , Sá Ingrid Soraya De Oliveira , Oliveira Ana Rebeca Soares Maia de , Carvalho Maria das Graças De , Teixeira Marlene Menezes de Souza
Published: November 2019

Neuroscience is a field of science that studies the central nervous system (CNS) as well as its relations with the human body.  It is intricately implicated in the different fields of knowledge, directly interfering in linguistics, the arts, medicine, among others.  Neuropsychology, in turn, deals with the study of the relationship between cognition, behavior and CNS activities, both under normal and pathological conditions.  This study aims to discuss aspects of neuroscience in order to clarify aspects related to how the brain learns and how it behaves in the learning process, so that the quality of pedagogical intervention can be reached.  Keywords: Neuroeducation, Neuroscience, Learning.
‘What can I already do well today?’ Competence development in innovative learning cultures
Authors: Barabasch Antje , Caldart Dominic , Keller Anna
Published: November 2019

Digitalisation and a rapidly changing labour market introduce new demands on competence and these demands reinforce the renewal of Swiss apprenticeship training in businesses. The telecommunication industry is a representative example of the new challenges that vocational education and training faces. This article highlights some new approaches and pathways to apprenticeships. It shows that not only structural conditions need to be adjusted, but also the learning culture of the community of practice, which includes the shared attitudes, values and beliefs of all the actors involved in vocational education and training. As this article indicates, comprehensive changes in the apprenticeships at the enterprise studied have had a substantial impact on the development of competences such as creativity, reflection, autonomous action and initiative-taking.
Factors influencing the intention of students at a selected TVET college in the Western Cape to complete their National Certificate (Vocational) Business Studies programme
Authors: Gaffoor Aasief , Van der Bijl André
Published: November 2019

Student dropout, also called ‘early departure’, is a significant problem in South Africa’s post-school education and training (PSET) landscape, specifically in the technical and vocational education and training (TVET) sector. The challenge of student retention and programme completion (the antithesis of dropping out) is equally significant and important to TVET institutions, the state department responsible (Department of Higher Education and Training) and the South African economy. Early departure negatively influences the success rates of educational institutions. It also influences the chances of personal employment and financial well-being of individual students, causing financial ripple effects on society and government. Students’ decisions to remain or leave college or a programme are influenced by a variety of individual and social factors, both internal and external, including people close to the students and the policies, systems and structures within which students interact. These factors also encompass the quality and friendliness of teachers, social interaction with teachers and peers, and the role played by friends in academic achievement. This article reports on a study of student perspectives on the internal and external factors that influence their retention in, and completion of, a TVET college Business Studies National Certificate (Vocational) (NC(V)) programme in the Western Cape, South Africa. An improved understanding of student experiences, intentions, and decision-making processes leading to persistence provides a foundation for improving student retention and programme completion in a TVET environment.
Agency, access and barriers to post-school education: The TVET college pathway to further and higher learning
Authors: Groener Zelda , Andrews Priscilla
Published: November 2019

Student access to technical and vocational education and training (TVET) colleges and pathways into higher education are critical issues in South Africa. Powell and McGrath (2014) draw on theories of agency to explain why students access TVET colleges. Using sociological and social–psychological theories of agency, our study explores a theoretical perspective on student access to TVET colleges, their barriers, success, and aspirations to study at university. We selected a TVET college in the Western Cape as our research site and interviewed 30 students who had completed the National Certificate in Educare. Our analysis of the data shows that the students had enrolled at the TVET college as an alternative pathway when barriers prevented their access to universities. Evidence shows that they also encountered barriers during the course of their studies but that, despite these barriers, their desire to study at university persisted. Theoretical insights derived from the empirical evidence suggest that student success at TVET colleges may provide them with prior learning and practical work experience in order to gain access to universities.
Handbook of vocational education and training: Developments in the changing world of work. In 2 volumes. Springer: Dordrecht.
Authors: Mulcahy Martin J
Published: November 2019

Why this handbook?The Handbook of vocational education and training: Developments in the changing world of work (‘the Handbook’) is as ambitious as it is significant. The editors have articulated the need for the Handbook as being a consequence of the ‘mushrooming of new journals, the expansion of the volume of research, and the widening of international cooperation by international Vocational Education and Training institutions’.5 The ambition of the Handbook is to provide a comprehensive overview of current thinking and scholarly writing in the field of vocational education and training (VET).
RUANG BERNORMA PADA HIMPUNAN SEMUA FUNGSI TERDEKATI
Authors: Aziz Abdul , Sumanto Y.D. , Solikhin Solikhin , Utomo Robertus Heri Soelistyo
Published: November 2019

In this paper, we discuss that in the approachable functions set can be defined a complete norm. Furthermore, we obtained that all of approachable functions set is a Banach Space.
A SECRET SHARING SCHEME BASED ON MULTIVARIATE POLYNOMIALS
Authors: Hartanto Ari Dwi , Sutjijana Sutjijana
Published: November 2019

A Secret sharing scheme is a method for dividing a secret into several partialinformation. The secret can be reconstructed if a certain number of partial information is collected. One of the known secret sharing schemes is the Shamir’s secret sharing scheme. It uses Lagrange interpolation (with one indeterminate) for reconstructing the secret. In this paper, we present a secret sharing scheme using multivariate polynomials with the secret reconstruction process using the multivariate interpolation formula derived by Saniee (2007). The resulted scheme can be considered as a generalization of the Shamir’s secret sharing scheme.
An elementary proof of Euler’s product expansion for the sine
Authors: Jha Sumit Kumar
Published: November 2019

We give a proof of the Euler’s infinite product for the sine using elementary
trigonometric identities, and Tannery’s theorem for infinite products.
Correlational study of the center of pressure measures of postural steadiness on five different standing tasks in overweight adults
Authors: Prasertsakul Thunyanoot , Kaimuk Panya , Chinjenpradit Wipawee , Charoensuk Warakorn
Published: November 2019

This study applied the posturography framework on five static standing tasks from the Berg Balance Scale (BBS). Thirteen participants were recruited and the trajectory data of the center of pressure (CoP) were collected. To analyze the postural performance, two approaches were taken: the scores from the BBS and statistical analysis. For the statistical analysis, Spearman’s method was applied to determine the correlation of CoP parameters. The results revealed the correlations between CoP parameters in the anterior-posterior (AP) and medial-lateral (ML) directions, and on the statokinesgram (SK) plane for all tasks. To obtain the in-depth detail between normal weight and overweight groups, the differences in the postural control mechanism were defined by correlations of CoP parameters. The Mann-Whitney U test was conducted to define the difference in postural control in terms of difference in weight gain and standing task factors, while Cohen’s d was used to investigate the influence of the difference in standing tasks and weight gain on postural control. The results showed that the correlations of CoP parameters could distinguish the balance impairment in the overweight condition from the normal postural control. Otherwise, the scores of BBS, the Mann-Whitney U test and Cohen’s d did not separate this slightly compensatory movement during equilibrium. Therefore, the correlations of CoP parameters could provide more information to analyze the balance function in each individual, especially in terms of slight compensation.
Remnant Mode Conversion Noise Suppression Using a Surface Mount Device Capacitor
Authors: Lee Seungjin , Lim Jaehyuk , Oh Sangyeol , Lee Jaehoon
Published: November 2019

A novel scheme to suppress the remnant mode conversion noise with a surface mount device (SMD) capacitor on dual back-to-back bent differential lines is proposed. To suppress the remnant mode conversion noise, an additional SMD capacitor is loaded on the differential lines between two bends to equalize even- and odd-mode velocities. The mode conversion noise suppression characteristics of the proposed scheme were analyzed and compared with various schemes. Also, eye diagrams confirmed that the addition of the SMD capacitor suppressed remnant mode conversion noise while preserving differential signal quality in dual back-to-back bent differential lines.
Country-specific euro area government bond yield reactions to ECB’s non-standard monetary policy program announcements
Authors: Fendel Ralf , Neugebauer Frederik
Published: November 2019

This paper employs event study methods to evaluate the effects of ECB’s non-standard monetary policy program announcements on 10-year government bond yields of 11 euro area member states. Measurable effects of announcements arise with a one-day delay meaning that government bond markets take some time to react to ECB announcements. The country-specific extent of yield reduction seems inversely related to the solvency rating of the corresponding countries. The spread between core and periphery countries reduces because of a stronger decrease in the latter. This result is confirmed by letting the announcement variable interact with the current spread level.
Assessment of Mating System in Helianthus annuus and H. petiolaris (Asteraceae) Populations
Authors: Gutierrez Agustina , Scaccia Baffigi Daiana , Poverene Monica
Published: November 2019

Helianthus annuus subsp. annuus and H. petiolaris are wild North American species that have been naturalized in central Argentina. They have a sporophytic self-incompatibility genetic system that prevent self-fertilization but the occurrence of self-compatible plants in Argentina was observed in both species and could in part explain their highly invasive ability. Their geographical distribution coincides with the major crop area. The domestic sunflower is self-compatible, can hybridize with both species and presents a considerable amount of gene flow. The aim of this study is to understand the self-incompatibility mechanism in both wild Helianthus species. Reciprocal crossing and seed production were used to identify self-compatible genotypes, the number and distribution of self-incompatibility alleles within populations and the type and extent of allelic interactions in the pollen and pistil. The behaviour of S alleles within each population was explained by five functional S alleles and one non-functional allele in each species, differing in their presence and frequency within accessions. In both species, the allelic interactions were of dominance/recessiveness and codominance in pollen, whereas it was only codominance in the pistil. Inbreeding effects in wild materials appeared in the third generation of self-pollination, with lethal effects in most plants. The number of S alleles is low and they behave in a similar way of other Asteraceae species. The self-compatibility was addressed to non-functional S alleles introgressed in wild Helianthus plants through gene flow from self-compatible sunflower.
A neonate with mucolipidosis II and transient secondary hyperparathyroidism
Authors: Leyva Carlos , Buch Maria , J. Wierenga Klaas , Berkovitz Gary , Seeherunvong Tossaporn
Published: November 2019

Background

Mucolipidosis II α/β (ML II) is an autosomal recessive disease associated with the abnormality of lysosomal enzyme trafficking.

Case presentation

We present an unusual patient with: (a) marked skeletal anomalies with secondary hyperparathyroidism; (b) serum intact parathyroid hormone level normalized by 7 weeks but abnormally elevated serum alkaline phosphate persisted; and (c) two mutations identified in the GNPTAB gene. One mutation, c.3503_3504delTC, is the most common mutation in ML II. However, the second mutation, c.2896delA, is a rare mutation for which clinical presentation has not been described previously.
Grain size issues in constructicon building – and how to address them
Authors: Zeschel Arne , Proost Kristel
Published: November 2019

Novel formats of construction-based description hold great potential for phenomena that fall through the cracks in traditional kinds of linguistic reference works. On the example of German verb argument structure constructions with a prepositional object, we demonstrate that a construction-based description of such phenomena is superior to existing lexicographic and grammaticographic treatments, but that it also poses a number of new problems. The most fundamental of these relates to the fact that construction-based analyses can be proposed on different levels of abstraction. We illustrate pertinent problems relating to the precise identification of constructional form and meaning and suggest a multi-layered descriptive format for web-based electronic reference constructica that can accommodate these challenges. Semantically, the proposed solution integrates both lumping and splitting perspectives on constructional grain size and permits users to flexibly zoom in and out on individual elements in the resource. Formally, it can capture variation in the number and marking of realised arguments as found in e.g. passives and transitivity alternations. Aspects of the theoretical controversy between Construction Grammar and Valency Theory are addressed where relevant, but our focus is on questions of description and the practical implementation of construction-based analyses in a suitable type of linguistic reference work.
The Opera nova la qual insegna a parlare Turchesco of Pietro Lupis: a Turkish–Italian glossary from about 1520
Authors: Schweickard Wolfgang
Published: November 2019

The article furnishes an edition with philological and lexical comment of the Italian-Turkish glossary Opera nova la qual insegna a parlare Turchesco of Pietro Lupis which dates back to about 1520.
L’intégration du vocabulaire des Documents linguistiques galloromans dans le DEAF électronique
Authors: Glessgen Martin , Dallas Marguerite
Published: November 2019

The exploitation of databases for lexical purposes has undergone extensive development during the first two decades of the 21st century. The methodological implications of this fruitful alliance between corpora and electronic dictionaries nonetheless deserve particular attention, the digital aspects as well as those pertaining to lexicology and metalexicography. The integration of the non-literary vocabulary of the Documents linguistiques galloromans into the database of the Dictionnaire Étymologique de l’Ancien Français (DEAFpré), currently in progress, provides an opportunity to illustrate the demands of a rigorous conception of computer-based lexicography (i. e. based on sound philological principles, ideally innovative, manual treatment of lexemes with a computer-assisted element, concentration on etymological, semantic and syntagmatic aspects). The case-study presented in this article focuses on the potential for interpretation afforded by corpus-based lexicography, its other main aim being an evaluation of the results and the cost in terms of time. The computerised system elaborated for this purpose can be extended to other projects, particularly those focusing on medieval Galloromania.
A second-order discretization for forward-backward SDEs using local approximations with Malliavin calculus
Authors: Naito Riu , Yamada Toshihiro
Published: November 2019

The paper proposes a new second-order discretization method for forward-backward stochastic differential equations.
The method is given by an algorithm with polynomials of Brownian motions where the local approximations using Malliavin calculus play a role.
For the implementation, we introduce a new least squares Monte Carlo method for the scheme.
A numerical example is illustrated to check the effectiveness.
Broadband multi-wavelength optical sensing based on photothermal effect of 2D MXene films
Authors: Zuo Yan , Gao Yerun , Qin Shiyu , Wang Zhenye , Zhou De , Li Zhen , Yu Yu , Shao Ming , Zhang Xinliang
Published: November 2019

Two-dimensional (2D) materials were widely used in sensing owing to the tunable physical or chemical properties. For years, optical sensing attracted a massive amount of attention on account of high accuracy, high security, non-invasive measurement, and strong anti-interference ability. Among the various optical sensing schemes, multi-wavelength optical sensing (MWOS) is an important branch and widely adopted in optical image, spectroscopy, or bio/chemical research. However, no spectral selectivity, limited working wavelength range, or intrinsic instability makes conventional 2D materials unsuitable for MWOS. A new class of 2D materials, known as MXene, exhibits outstanding electronic, optical, and thermal properties, leading to new applications in optical sensing. In this paper, we propose an integrated photothermal optical sensor (PHOS) using Ti3C2Tx MXene films. Thanks to the inherent spectral dependence of Ti3C2Tx MXene over a broadband range, the proposed PHOS can respond to different wavelengths from visible to short-wavelength infrared. Because of the efficient photothermal conversion, the PHOS has a control efficiency up to 0.19 π · mW−1 · mm−1 under 980-nm laser pumping and shows a higher control efficiency under red light (690 nm) irradiation. The measured response time of the proposed PHOS is 23.4 μs. This paper brings MXene into chip-integrated optical sensing fields for the first time and shows the potential applications.
Optical binding of nanoparticles
Authors: Forbes Kayn A. , Bradshaw David S. , Andrews David L.
Published: November 2019

Optical binding is a laser-induced inter-particle force that exists between two or more particles subjected to off-resonant light. It is one of the key tools in optical manipulation of particles. Distinct from the single-particle forces which operate in optical trapping and tweezing, it enables the light-induced self-assembly of non-contact multi-particle arrays and structures. Whilst optical binding at the microscale between microparticles is well-established, it is only within the last few years that the experimental difficulties of observing nanoscale optical binding between nanoparticles have been overcome. This hurdle surmounted, there has been a sudden proliferation in observations of nanoscale optical binding, where the corresponding theoretical understanding and predictions of the underlying nanophotonics have become ever more important. This article covers these new developments, giving an overview of the emergent field of nanoscale optical binding.
Violence and Avoidance Behavior: The Case of the Mexican Drug War
Authors: Balmori de la Miyar Jose Roberto
Published: November 2019

This paper examines the effect of violence, originated from the Mexican Drug War, on avoidance behavior. The analysis uses three different variables to capture avoidance behavior by easiness to do, during the past year: refrained from going out at night (easy-to-avoid), refrained from carrying cash (medium-to-avoid) and refrained from using public transportation (hard-to-avoid). Data comes from different government sources and crime victimization surveys. Results suggest a violence effect of 6.72% on refrained from going out at night, 3.52% on refrained from carrying cash and 1.20% on refrained from using public transportation.
Introducing the Human Rights Violations Dataset for the Kurdish Conflict in Turkey, 1990–2018
Authors: Mousseau Demet Yalcin , Napolitano Justin , Olsen Alex
Published: November 2019

This study introduces a new event dataset on the human rights violations in the Kurdish conflict in Turkey perpetrated by both the State and the armed rebel group, the PKK (the Kurdistan Workers Party), from 1990 to 2018. The dataset codes human rights violation events that victimize civilians, including women and children, identifying the perpetrator, type of victim, type of human right violation, and the place of the violation. The categories of human rights violations include the physical and political rights drawn from the laws and treaties adopted by the U.N., such as killings or deaths of civilians, illegal detention and arrests, and freedom of peaceful assembly. The dataset is useful in examining the trends and motives of perpetrators in committing these violations and for seeking to understand the extent to which state and non-state rebel groups abide by international norms in armed conflicts. The framework of this dataset, although developed for the Kurdish conflict, is applicable and can be extended to other armed conflict cases, facilitating cross-conflict research on a more comparative basis.
Reliable Sn–Ag–Cu lead-free melt-spun material required for high-performance applications
Authors: Jubair Mohammed Mundher , Gumaan Mohammed S. , Shalaby Rizk Mostafa
Published: November 2019

This study investigates the structural, mechanical, thermal and electrical properties of B-1 JINHU, EDSYN SAC5250, and S.S.M-1 commercial materials, which have been manufactured at China, Malaysia, and Germany, respectively. The commercial materials have been compared with the measurements of Sn–Ag–Cu (SAC) melt-spun materials that are only indicative of what can be expected for the solder application, where the solder will have quite different properties from the melt-spun materials due to the effects of melt-spinning technique. Adding Cu to the eutectic Sn–Ag melt-spun material with 0.3 wt.% significantly improves its electrical and mechanical properties to serve efficiently under high strain rate applications. The formed Cu3Sn Intermetallic compound (IMC) offers potential benefits, like high strength, good plasticity, consequently, high performance through a lack of dislocations and microvoids. The results showed that adding 0.3 wt.% of Cu has improved the creep resistance and delayed the fracture point, comparing with other additions and commercial solders. The tensile results showed some improvements in 39.3% tensile strength (25.419 MPa), 376% toughness (7737.220 J/m3), 254% electrical resistivity (1.849 × 10−7Ω · m) and 255% thermal conductivity (39.911 w · m−1 · k−1) when compared with the tensile strength (18.24 MPa), toughness (1625.340 J/m3), electrical resistivity (6.56 × 10−7Ω · m) and thermal conductivity (11.250 w · m−1 · k−1) of EDSYN SAC5250 material. On the other hand, the Sn93.5–Ag3.5–Cu3melt-spun solder works well under the harsh thermal environments such as the circuits located under the automobiles’ hood and aerospace applications. Thus, it can be concluded that the melt-spinning technique can produce SAC melt-spun materials that can outperform the B-1 JINHU, EDSYN SAC5250 and S.S.M-1 materials mechanically, thermally and electrically.
New Exact Axisymmetric Solutions to the Navier–Stokes Equations
Authors: Bogoyavlenskij Oleg
Published: November 2019

Infinite-dimensional space of axisymmetric exact solutions to the Navier–Stokes equations with time-dependent viscosity

ν

(
t
)

$\nu(t)$

is constructed. Inner transformations of the exact solutions are defined that produce an infinite sequence of new solutions from each known one. The solutions are analytic in the whole space ℝ3
and are described by elementary functions. The bifurcations of the instantaneous (for

t
=

t
0

$t={t_{0}}$

) phase portraits of the viscous fluid flows are studied for the new exact solutions. Backlund transforms between the axisymmetric Helmholtz equation and a linear case of the Grad–Shafranov equation are derived.
Magnetogel Nanospheres Composed of Cisplatin-Loaded Alginate/BCyclodextrinas Controlled Release Drug Delivery
Authors: Darini Ali , Eslaminejad Touba , Nematollahi Mahani Seyed Noroddin , Ansari Mehdi
Published: November 2019

Purpose: The main aim of the present study was to design, fabrication and physicochemicalcharacteristics of the magnetogel nanospheres as carriers for Cisplatin in the in vitro environment.Methods: Magnetic nanospheres were synthesized by using a chemical co-precipitation methodand coated by sodium alginate through double emulsion method. Then cisplatin was encapsulatedinto β-cyclodextrin -sodium alginate grafted magnetic nanospheres. The physicochemicalproperties of the sodium alginate grafted magnetic nanospheres were characterized by using FTIR,particle size analyzing, vibrating sample magnetometry, thermogravimetric and SEM analysis.Also the drug entrapment efficiency, content and in vitro release profile were investigated.Results: Size distribution results revealed that the particles size was distributed in the rangeof 50± nm. Also morphological properties showed that particles are separated and sphericalwith the grafted layers of the polymer. The release profile data were in the acceptable rangecompared to the blank (cisplatin solution).Conclusion: It could be concluded that the sodium alginate grafted magnetic nanospheres couldact as a slow and controlled release system to deliver cisplatin.
Preparation and Evaluation of Eudragit® L100 Nanoparticles LoadedImpregnated with KT Tromethamine Loaded PVA -HEC Insertions forOphthalmic Drug Delivery
Authors: Mohammadi Ghobad , Mirzaeei Shahla , Taghe Shiva , Mohammadi Pardis
Published: November 2019

Purpose: The purpose of the present study was to improve the ocular delivery for ketorolactromethamine (KT) used to treat inflammation of the eye.Methods: Eudragit nanoparticles loaded with KT were prepared and incorporated in polyvinylalcohol (PVA) and hydroxyethyl cellulose (HEC) films. Nanoparticles were characterized byFourier transform-infrared (FT-IR), scanning electron microscopy (SEM). Physicochemicalproperties and encapsulation effciency were investigated for nanoparticles. Also, the insertswere evaluated for their physiochemical parameters like percentage moisture absorption,percentage moisture loss, thickness and folding endurance.Results: Mean particle size and zeta potential were in range of 153.8-217 nm and (-10.8) -(-40.7) mV, respectively. The results show that the use of a surfactant has not led to any majorchange on drug loading. The loading increases with the amount of polymer. The insert had athickness varying from 0.072 ± 0.0098 to 0.0865 ± 0.0035 mm. The thicknesses of the insertsand the folding endurance increased with the total polymer concentration. The physicochemicalproperties showed that the Eudragit® L-100 nanoparticles loaded PVA-HEC films could be aneffective carrier for KT.Conclusion: For the first time, inserts of Eudragit nanoparticles were successfully prepared forophthalmic drug delivery system to prevent frequent drug administration and enhance patientcompliance.
Preparation and Characterization of Silk Fibroin Nanoparticles as a Potential Drug Delivery System for 5-Fluorouracil
Authors: Rahmani Hamid , Fattahi Ali , Sadrjavadi Komail , Khaledian Salar , Shokoohinia Yalda
Published: November 2019

Purpose: The aim of this study is to prepare 5-fluorouracil (5-FU) loaded silk fibroin nanoparticles(SFNPs) and to achieve a controlled release delivery system with the high loading capacity. Methods: SFNPs with 1:1, 1:3, and 1:10 ratios of 5-FU to silk fibroin were prepared. SFNPswere characterized by Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD)analysis, Scanning electron microscope (SEM), and Transmission electron microscope (TEM).Loading efficiency, in vitro release, and cell viability were studied for optimal SFNPs. Results: The ratio of 1:1 was optimal formulation with the size and polydispersity index (PDI)of 221.03 nm and 0.093 before freeze drying, and 286.7 nm and 0.154 after freeze dryingby lactose, respectively. The loading efficiency and loading content of this ratio were 52.32%and 34.35%, respectively. FT-IR and XRD analysis indicated the conformational change (fromrandom coil to β-sheet) in the structure of nanoparticles by increasing amount of the drug, whichcaused the smaller size, the higher loading efficiency, and the slower release pattern. The drugloadednanoparticles reached to the half maximal inhibitory concentration (IC50) that werecomparable with free drug on MCF7 (human breast cancer) cell line. Conclusion: This study was planned to achieve a promising controlled release drug deliverysystem for carrying 5-FU, as a potent anticancer drug. SFNPs were found proper candidates fordelivery of a hydrophilic drug such as 5-FU.
The Comparison Between the Mutated HuIFN-β 27-101 and the WildType Interferon β: the Comprehensive In Silico Study to Evaluate theEffect of Mutations on IFN-β
Authors: Balkhi Sayed Sharif , Hojati Zohreh
Published: November 2019

Purpose: Interferon beta (IFN-β) is used to combat multiple sclerosis (MS) disease. CreatingR27T and V101F mutations (mHuIFN-β-27 and mHuIFN-β-101) is one of the tasks performedto improve human interferon beta (HuIFN-β) half-life, function and expression. In this work,the impact of R27T and V101F mutations in recombinant IFN-β on its binding to interferonreceptors were studied by molecular docking.Methods: This work was performed through in silico study. The simulation of mutation wasperformed using the online Rosetta Backrub software and checked using server verify3D.Comparison of access to the solvent of the amino acids in the structures created was performedusing the asaview online server. Also, the effect of mutations on the fold of the protein wasreviewed by the online HOPE server. The molecular docking was performed between HuIFN-βand the external region of IFNAR receptor using the online ClusPro2 protein-protein dockingserver.Results: The comparison of the values of the negative binding energy (ΔGbind) obtained fromprotein-protein molecular docking between IFNAR receptor and HuIFN-β, mHuIFN-β-27,mHuIFN-β-101 and mHuIFN-β-27-101 ligands did not show a significant difference, and thesedifferences do not see any meaningful relationship between them (P > 0.9999).Conclusion: Regarding these results, it can be concluded that these mutations do not have anegative effect on the composition of the complex rHuIFN-β/IFNAR. So, they do not interferewith the binding of the IFN-β to the receptor. It is concluded that the quality of the rHuIFN-β isimproved by introducing these two mutations.