bluuebunny/crossref_metadata_2025 huggingface dataset:
On the mechanism of instability in a two-layer system with limited solubility of components
Authors:   Institute of Continuous Media Mechanics UB RAS, Mizev А. I. , Mosheva Е. А. ,   Institute of Continuous Media Mechanics UB RAS, Oshchepkov V. O. ,   Institute of Continuous Media Mechanics UB RAS
Published: June 2021

A two-layer system of miscible liquids is a common model system in studies of both fundamental and applied problems in hydrodynamics that associated with stratified media. Rayleigh-Taylor instabilities or double diffusive one can lead to a disturbance in mechanical equilibrium if both or at least one of the components dissolved in each of the layers are initially unstable stratified. The situation when both components have a stable initial density distribution is believed that absolutely stable and, usually, is not considered by researchers. This paper experimentally demonstrates the possibility of developing instability in such systems and proposes a physical mechanism based on the dependence of the solubility of one of the components on the concentration of the second component. It is shown that the evolution of the density profile, the possibility of the development of instability, and the properties of the arising convective motion are determined by the initial position of the system on the parameters plane of the solubility diagram.
Electromagnetic measurement of level and conductivity of non-ferrous metals
Authors:   Institute of continuous media mechanics UB RAS, Losev G. L. , Eltishchev V. A. ,   Institute of continuous media mechanics UB RAS
Published: June 2021

The paper presents the developed electromagnetic non-invasive level and electrical conductivity sensors for non-ferrous and alkali metals. The influence of the geometry of the installations on the measurement accuracy was experimentally determined. The limits of permissible errors in the positioning of the sensors relative to the analyzed volumes of metals are established.
Experimental study of rheological properties of liquids for hydrofracturing
Authors:   Institute of Continuous Media Mechanics UB RAS, Efremov D. V. , Bannikova I. A. ,   Institute of Continuous Media Mechanics UB RAS, Bayandin Y. V. ,   Institute of Continuous Media Mechanics UB RAS, Krutikhin E. V. ,   POLYEX, Zhuravlev V. A. ,   POLYEX
Published: June 2021

The work is devoted to the study of the rheological behavior of proppant carrier fluids used for hydraulic fracturing (HF) technology in order to increase oil recovery, including from hard-torecover oil and gas reserves, in a wide range of deformation rates using viscometers of various designs. Rheological properties were studied for proppant carrier fluids based on guar and Surfogel grade D, (type 70–100, produced by JSC “Polyex”) with comparable shear rate 128 s–1. Quasistatic experiments to determine the values of the dynamic viscosity of the liquids under study were carried out using a falling ball viscometer (according to the Stokes method). Using an original viscometer, consisting of two coaxial cylinders (rotary rheometer), the dynamic viscosity of surfogel was investigated in a wide range of shear rates. The viscoelastic properties of surfactants were studied using a Physica MCR501 rheometer, which has a plane-to-plane measuring system and allows rheological studies in rotational and oscillatory modes. A comparison of the rheological properties of fluids based on the guar and the viscoelastic surfactant is carried out and it is established that a fluid based on the viscoelastic surfactant has a higher dynamic viscosity and does not lose its elastic properties, which is an certain advantage over a fluid based on the guar.
Structure, physical and chemical properties of near-surface layers of optical materials modified by treatment in hydrogen plasma
Authors:   Perm Nanotechnologies LLC, Salgaeva U. O. , Volyntsev A. B. ,   Perm State University, Mushinsky S. S. ,   Perm Scientific-Industrial Instrument Making Company
Published: June 2021

The present paper aims to investigate the structure and properties of the near-surface layers of optical materials modified by treatment in hydrogen plasma (H-plasma). For this the quartz and soda-lime glasses, lithium niobate (LN) as delivered and LN after proton exchange were used. The structure and properties of the near-surface layers of optical materials were investigated by IR spectroscopy, Raman spectroscopy, X-ray diffraction analysis, atomic force microscopy, mode spectroscopy, scanning electron microscopy, and wet chemical etching. During the treatment in H-plasma the hydrogen penetrated into the near-surface layers and caused increasing the number of defects in the structure of materials. Changes of the shape and intensity of the absorption peaks of OH–-groups and the θ/2θ- curves recorded from the LN samples processed in H-plasma were inconsequent, probably due to the thin modified layer. For the first time, a huge volume “swelling” (above 10 %) of the near-surface layers of LN and soda-lime glass after the processing in H-plasma was revealed. Also for the first time, the formation of thin strained layers on the surface of the LN after treatment in H-plasma was shown; the density reduction of the near-surface layers of the LN modified in H-plasma was described; the features of blistering and flaking were found on the surface of LN and soda-lime glass after their treatment for a long time (120–150 min). For the first time, the multilayer structure of the near-surface region of the LN was detected after treatment in H-plasma. In this paper we proposed the model of changes the structure and properties of LN after the treatment in H-plasma. The model explains the experimental results obtained in this study and previously published studies of other research groups. Due to the high concentration in the near-surface layers of optical materials after the H-plasma treatment, hydrogen predominantly forms pores and bubbles. Presumably the compounds of the Li2O–Nb2O5 system with a low Li content formed in the near-surface region of LN after the treatment in H-plasma. Modification of near-surface layers of optical materials in hydrogen plasma could be used to form elements of integrated-optical circuits, particularly the diffraction gratings.
On a role of anisotropy and nonlinear diffusive effects during the construction of waveguides in the lithium niobate
Authors:   Perm State University, Demin V. A. , Petukhov M. I. ,   Perm State University, Ponomarev R. S. ,   Perm State University,   Perm Federal Research Center UB RAS, Topova A. V. ,   Perm State University
Published: June 2021

Direct numerical simulation of a process of hydrogen diffusive intrusion into the lithium niobate monocrystal is fulfilled with reference to the manufacturing two-channel system of waveguides. The calculations were carried out according to the technology of waveguides production, taking into account the presence of several stages, which at first include the material saturation with the protons by treating the working surface with the melt of benzoic acid, and then annealing the sample. The contribution of the nonlinear diffusion to the process of the waveguide shaping is analyzed. It is shown that the formation of a stepped waveguide boundary is significantly influenced by the procedure of monocrystal annealing. Heretofore, the annealing stage was not quantitatively investigated. It can be emphasized that the attention has not been paid to the possible role of the annealing on formation of the sharper boundary between the waveguide and its mother substrate. A theoretical model of anisotropic diffusion in a solid material is constructed on the basis of experimental data, which indicate the presence of a transitional surface layer with pronounced regular mesostructural directions in the polished lithium niobate monocrystal. Based on the derived equations, the waveguides shape in a cross-section was simulated numerically for different values of inclination angle of the main axes with respect to the cut lines of the crystal. It is demonstrated that in the region of the waveguide bifurcation, when at the stage of protons intrusion the interaction of diffusive fluxes is possible, the diffusion anisotropy can lead to a breakdown of the waveguides symmetry, which can affect their optical properties.
Frozen wave simulation by the lattice Boltzmann method
Authors:   Perm State University, Volodin I. V. , Alabuzhev A. A. ,   Institute of Continuous Media Mechanics UB RAS
Published: June 2021

The dynamics of two-layer system of immiscible liquids under the action of horizontal linear vibrations in the field of gravity was investigated. The numerical simulation was carried out by the lattice Boltzmann method (LBM) with model D2Q9. For the first time LBM was used to achieve the appearance of frozen wave (quasi-stationary relief) at the interface of two fluids. There are two types of boundary conditions for the sidewalls: a periodic condition for comparison with analytical results and no-slip condition for comparison with experiments. Various computational domains were considered. Both cases with the same viscosities of both phases and different viscosity ratios were studied. HCZ model was used to describe two-phase system and the interface of two liquids. The presence of a frozen wave on the interface of liquids was found. The dependence of liquids viscosity on the relief was studied. The obtained critical wave number coincides well with the theoretically predicted value for liquids with the equal viscosity and vanishing viscosity. The results of numerical calculations show a weak viscosity effect for a more viscous lower liquid. However, the destabilizing effect of viscosity is more significant for a more viscous upper liquid.
Simulation of oil cooling of a submersible motor using a heat exchanger
Authors:   Perm National Research Polytechnic University, Gizatullin R. R. , Peshcherenko S. N. ,   Perm National Research Polytechnic University, Lykova N. A. ,   «Novomet-Perm»
Published: June 2021

Submersible motors are part of submersible oil production pumps that convert electrical energy, which is supplied through a cable from VSD, into mechanical energy of pump rotation. Currently, in about 30% of cases, the failure of an electrical submersible pump is due to a failure of the submersible motor. One of the main causes of failures is overheating of the stator winding insulation. Overheating of submersible oil-filled electric motors occurs because more heat is generated inside the motor than is removed through its outer surface. To intensify the heat removal, it is proposed to connect a heat exchanger in series with the motor and to organize the circulation of the oil in a closed loop. Both in the submersible motor and in the heat exchanger, oil flows along the annular gap along the inner surface of the housing, the oil channel is closed through a hole inside the shaft. The aim of the work is to select such a configuration of the annular channel, in which its length would be minimal. Intensification of heat removal by increasing the speed of the coolant is not advisable, because requires the motor to be equipped with a powerful pump for pumping oil, which will become an additional source of heat. Therefore, it was decided to increase the surface area of the annular channel through which heat, through the body of the installation, is removed to the well fluid. A series of calculations was performed for heat exchangers with smooth walls, with fins (perpendicular to the flow direction), and with spiral grooves (which additionally increase the length of the trajectory of oil particles and the time of their thermal contact with the stacks of the heat exchanger body). Computational fluid dynamics calculations showed that heat exchangers made according to the first two design options removed less than half of the heat. According to the third option, the oil was cooled practically to the temperature of the well fluid with a heat exchanger length of about 10% of the submersible motor length.
THE ONEIRIC SPACE OF KAZUO ISHIGURO’S NOVEL ‘THE BURIED GIANT’
Authors:   Immanuel Kant Baltic Federal University, Mikheikina Alina A.
Published: June 2021

The article provides a detailed study of the fictional space of Kazuo Ishiguro’s novel The Buried Giant. There are identified the features that give this aspect of the chronotope of the novel an oneiric character. Particular attention is paid to the analysis of certain loci of the novel’s fictional space, their toponymic and semiotic characteristics. Among the artistic means that actualize the oneiric space in the text, there are distinguished the peculiarities of the narrative level (first-person narration, representation of the events through the consciousness of the characters) and the features of the artistic expression and visualization of the novel’s fictional world: incorporation of mythological elements, metaphorization and generalization of the fictional space, emphasis on its horizontal and vertical organization. Some of the mythological characters are considered in the paper in terms of the additional meanings they contribute to the novel. Some motifs actualized by incorporation of mythological elements are also examined. A comprehensive analysis allowed us to reveal that the oneiric nature determines the topological characteristics of the novel. In addition, the oneiric space in The Buried Giant performs the function of representing the work of mnemonic mechanisms, which determines the connection of the considered aspect of poetics with the author’s intention, as well as with the theme of memory, characteristic not only of the analyzed novel but of the writer’s works as a whole. The study has also revealed an analogy in the representation of the chronotope with previous works by Kazuo Ishiguro, which allows us, among other things, to conclude that the actualization of the oneiric space is an important feature of the author’s artistic method.
THE VOICE PHENOMENON IN BECKETT’S FRENCH-LANGUAGE SHORT STORIES
Authors:   Southern Federal University, Semenchenko Iurii I.
Published: June 2021

The article deals with the specific features of the voice phenomenon representation and the peculiarities of its functioning in French-language short stories written by Beckett, namely in Premier amour (First Love), Le calmant (The Calmative) and Au loin un oiseau. The abovementioned texts allow us, on the one hand, to demonstrate the genesis of the writer’s artistic and aesthetic principles of representing the studied phenomenon, which were later reflected in theatrical, radio and television plays, and, on the other hand, – to shed light on the specificity of the literary world of these texts. The research conducted allows us to conclude that in all the analyzed texts the voice is captured in different forms of representation and has a varying (from text to text) functionality. In Premier amour, there is a feminine voice asking to restore the corporeality and individuality of its origin. However, the stamp of convulsiveness in the heroine’s voice paradoxically has its source not in the corporeal but in the ideal. In Le calmant, the protagonist’s feebleness, expressed by the signs of his corporeal conditions, is doubled by his aphony, which thus transcends one of the most important motifs for Beckett’s writing – that of human weakness. This motif also reveals here another shade of meaning – weakness as a ‘respite’ from the suffering which human existence bears. Finally, in Au loin un oiseau we see a ventriloquist character. Due to the ‘I’ living inside, the ‘He’ is becoming similar to ventriloquists. Unlike them, however, his speaking capacity is under control of the narrator.
WILLIAM BLAKE IN THE SOVIET RECEPTION: FORMING THE IMAGE OF ‘REVOLUTIONARY ROMANTIC’
Authors:   ‘Analitika Rodis’ Publishing House, Serdechnaia Vera V.
Published: June 2021

The article is devoted to a scantily explored aspect of the Russian reception of William Blake: the justification of the poet in Soviet criticism as a ‘revolutionary Romanticist’. The purpose of the article is to characterize strategies for understanding the heritage of William Blake by Soviet critics. Soviet Blake was officially ‘born’ in 1957 – after the World Peace Council’s decision on celebrations of the poet’s bicentennial. Blake, with a reputation tainted by the Symbolists, needed serious justification in Soviet literary criticism. The arguments for his justification were the revolutionary pathos of his poems, his democratic background and his humanism. It was important to emphasize Blake’s proximity to the working class. To introduce Blake into the literary field of Soviet criticism, it was necessary to justify his religiosity; the key to this justification was his humanism and the democracy of his faith. Blake’s prophetic poems were interpreted as the product of creative decline generated by the poet’s tragic social loneliness. Soviet criticism condemned Balmont’s translations and praised Marshak’s ones. Making Blake primarily a revolutionist, Soviet critics came to unexpected comments close to vulgar sociologism. In Soviet criticism, Blake was a missing link in the development of the ‘revolutionary’ chain of anti-tyrannical poetry. The author of the paper collects and classifies references to Blake in Soviet literary and artistic criticism, introduces some little-known facts of reception, classifies and generalizes the Soviet view of Blake as a ‘revolutionary Romanticist’, characterizes the genesis and content of this approach. The author applies the cultural-historical and comparative-historical methods as well as the principles of receptive aesthetics.
SPECIAL FEATURES OF GRAPHIC NOVELS TRANSLATION
Authors:   Perm State University, Khrustaleva Mariya A. , Klimova Aleksandra S. ,   Perm State University
Published: June 2021

The article deals with one of the issues in the study of creolized text – the special features of graphic novels translation. These are explored based on the translation from Spanish into Russian made by the authors of the paper for the literary work Wrinkles (Spanish: Arrugas) written by Paco Roca. The authors consider cognitive discourse analysis to be the main approach to the translation of the abovementioned graphic novel. It gives an opportunity not only to justify the researchers’ translation decisions but also to convey the author’s idea and his personal perception of the world in a more complete and accurate way. The frame method, which is regarded as an adequate mode of the concept structural organization, makes it possible to build the sphere of concepts of the source text. The concepts of MEMORIA (memory) and VEJEZ (old age) are considered the key concepts of the graphic novel because, as it was found at the stage of pre-translation analysis, they create its artistic space. The frame analysis of the fundamental concepts of the source text and the identification of semantic correlations between the language representants make it possible to translate the researched literary work. Based on the research results, the authors draw a conclusion about the special features of graphic novels translation and the effectiveness of applying the cognitive discourse analysis to the translation of such works. The study concludes with an outline of the prospects for further research on graphic novels, a new literary genre that represents an unusual combination of fine art, literature and cinematography.
‘WHY’ QUESTIONS AS A COHESIVE FACTOR IN ‘WATERLAND’ BY G. SWIFT
Authors:   Perm State University, Gladkova Katerina Yu.
Published: June 2021

The article deals with the problem of relation of two linguistic categories – interrogativity and text cohesion – in a literary text. The aim of the research is to study the role of ‘why’ questions in text cohesion in Waterland by G. Swift. As part of the study, a database of interrogative contexts was formed, which includes general questions, special questions and disjunctive questions. Methods of semantic analysis, stylistic analysis, contextual analysis, syntactical analysis were used in the research process. The paper provides the results of analysis conducted to reveal the functions of ‘why’ questions in text cohesion on the micro-level (lexical and semantical cohesion, syntactical cohesion) and macro-level (plot and composition, imagery, themes and idea) of the literary text. There were found means of text cohesion such as lexical and syntactical repetitions. On the level of lexis, such various types of repetition were discovered as complete lexical repetition, partial repetition, synonymic and antonymic repetition, deixis, repetition of the interrogative adverb ‘why’. On the level of syntax, the analysis demonstrates a tendency to formal incompleteness of interrogative structures, on the one hand, which allows us to assume an implicit type of text cohesion, and, on the other hand, a tendency to formal complexity of interrogative structures, with parenthetic clauses, adverbial participial phrases and homogeneous parts of the sentence being frequently used. Stylistic analysis of ‘why’ questions shows that anaphora, antithesis, syntactical parallelism, parenthesis, ellipsis and aposiopesis are among the means of text cohesion in the text under consideration. The analysis of the novel on the macro-level demonstrates that ‘why’ questions function in the plot development, facilitate semantical cohesion between chapters, form thematical and conceptual unity of the literary text, and serve to promote the unity of imagery. The author concludes that ‘why’ questions facilitate the processes of semantical and syntactical compression, which are considered the main mechanisms of text production.
KNOWLEDGE AND USAGE OF LOCAL LEXIS IN PERM KRAI: 1980s – 1990s vs 2020
Authors:   Perm State University, Erofeeva Elena V. , Yushkova Svetlana E. ,   Perm State University
Published: June 2021

The article discusses the changes that have occurred over the past 30 years in the knowledge and usage of local lexical units in Perm Krai. In the 1980s – 1990s, T. I. Erofeeva carried out a study of native speakers’ competence in local lexis (localisms) and its dependence on the speakers’ social parameters. The questionnaire method was used for collecting the material, the ANOVA method was applied for its analysis. The authors of the article conducted a similar study using the same lexical material at the present time. Comparison of the results received in the 1980s – 1990s and in 2020 showed that the level of knowledge and usage of localisms in Perm Krai has markedly reduced; moreover, the number of social factors that have statistically significant influence on the knowledge and usage of localisms has decreased: at present, both the knowledge and the use of localisms are only affected by one of the factors considered – the ‘age’ factor. The received result can be explained by two reasons: firstly, opening of territorial and social boundaries in the current context leads to a decrease in the number of local lexical elements in speech; secondly, the set of Perm Krai localisms has changed over the past 30 years. In both cases, changes in the language and its use are observed.
CHARACTERISTICS OF THE POLYSEMIC NOUN «REAL’NOST’» IN RUSSIAN NEWSPAPER TEXTS
Authors:   Lomonosov Moscow State University, Shuchun Zhang
Published: June 2021

In this paper, the abstract noun real’nost’ is studied based on the newspaper texts included in the electronic corpus ‘Russian Newspapers of the End of the 20th Century’, developed by the Laboratory for General and Computational Lexicology and Lexicography, Lomonosov Moscow State University. The studied word, as well as other polysemic nouns formed with the productive suffix -ost’, may obtain regular concrete meanings besides the meaning of abstract attribute. Due to the polysemic nature of this particular type of nouns, contexts play a rather significant role in understanding and studying them. The purpose of the paper is to identify the semantic and contextual characteristics of the given noun while being used in different meanings in newspaper texts. Based on the corpus data, we have revealed the most frequently used meaning of the word and the contextual characteristics of each particular meaning. The study has shown that in Russian newspaper texts created in the late 20th century, the concrete meaning of the word real’nost’ demonstrates a considerably higher usage frequency than its abstract meaning. The noun also developed a third meaning, as a result of which it can be used in the plural form. In addition, the studied word has been analyzed in a comparative perspective. When it is used in the position of the subject or an actant in original texts in Russian, its abstract meaning can only be expressed by predicates or attributes (subordinate clauses) in Chinese. This proves that the Russian language has a comparatively higher level of ‘communicative fragmentation’, which is mainly based on nouns formed with the suffix -ost’.
MODERN POETIC DISCOURSE: THE LINGUISTIC NATURE OF HERMETICISM
Authors:   Samara National Research University, Kuchumova Galina V.
Published: June 2021

The paper provides review of the monograph by Ekaterina Evgrashkina The Semiotic Nature of Semantic Uncertainty in Modern Poetic Discourse (based on German and Russian poetry), published in the Russian language as part of the series NEUERE LYRIK. Interkulturelle und interdisziplinäre Studien. Herausgegeben von Henrieke Stahl, Dmitrij Bak, Hermann Korte, Hiroko Masumoto und Stephanie Sandler. BAND 5. Berlin: Peter Lang, Internationaler Verlag der Wissenschaften, 2019. 173 s. ISBN 978- 3-631-78193-7. The monograph deals with the main trends of German and Russian poetry of the last decades. The focus is on the phenomenon of hermetic poetry. Modern authors consciously choose writing strategies such as literary improvisation, language play, and various intermedial inclusions. The first chapter ‘The problem of poetic meaning’ provides a theoretical framework for the field of research. It introduces the definitions of discourse, the concepts ‘language games’ (developed by L. Wittgenstein), ‘text / discourse’, ‘text / work’, dialogical dimensions of poetic text. The second chapter ‘Semiotics of modern poetry’ covers the concept ‘mobile semiosis’ (J. Baudrillard) and some others. In hermetic poetic discourse, generation of meaning is based on mobile semiosis, in which the relationship of stability between the signifier and the signified is called into question. In The Role of the Reader, Umberto Eco describes two models of the reader, different strategies for interpreting text. Susan Sontag denies the possibility of final interpretation of a text, she suggests eroticism of art instead of hermeneutics. The third chapter ‘Linguistic installations’ considers various manifestations of poetic Hermeticism in modern poetry, the experience of concrete and visual poetry in German: Timm Ulrichs (1940), Klaus Peter Dencker (1941), Barbara Köhler (1959), Werner Herbst (1943–2008), Anatol Knotek (1977), Herta Müller (1953). The final chapter ‘The self-reflexive discourse’ deals with the trend of modern poetry towards free verse and construction of new complex poetic forms. The process of occasional word formation is shown in the lyrical texts by German poets Thomas Kling (1957–2005), Lutz Seiler (1963), Konstantin Ames (1979), Lioba Happel (1957), Thomas Böhme (1955), and by Russian authors Polina Andrukovich (1969), Alexander Ulanov (1963), Dmitry Vorobyov (1979). In poetic discourse, the constitution of the poetic subject correlates with the introduction of new elements of culture into the poetic text. Such innovations do not lead to a mechanical increment of the elementary meaning, but to a structural transformation of the whole picture. The reviewed monograph is significant in that it provides theoretical understanding of individual poetic practices and the analysis of specific empirical material – the latest German and Russian poetry.
COVID-19 Diagnoses: A Source of Immanent Value and Novelty
Authors: Rosengarten Marsha
Published: June 2021

Although the body is fundamental to observation and feeling, its experience of infection is regarded by the biomedical sciences and, for the most part, the social sciences as relatively obtuse. The body is situated as a mere object of inquiry, as if its intricate and highly complex dynamics indicate that it is no more than an imperfect animated machine and, concomitantly, infection simply a change to its normative mechanisms. In this Position Piece, I ask: what might be afforded to the problematic diagnosis of communicable infection and to global health strategies of containment if the body were appreciated as an active participant in diagnoses? To do so, I take up the ‘pluralist panpsychist’ proposition that bodies think. Counter to the view that thinking is the preserve of the human mind and that value is an ‘after’ ascribed to a given fact or situation, I experiment with the idea that the body’s sensory awareness can be thought as a creative source of immanent values. Drawing on a series of empirical examples primarily focused on the perceived novelty of COVID-19, I offer a preliminary sketch of how revaluing the body as involved in decision-making and novelty might enrich the scope of biomedical and social diagnoses.
Long noncoding RNA FAM225B facilitates proliferation and metastasis of nasopharyngeal carcinoma cells by regulating miR-613/CCND2 axis
Authors: Dai Weijun , Shi Yi , Hu Weiqi , Xu Chenjie
Published: June 2021

Growing evidence has suggested that abnormally expressed long non-coding RNAs (lncRNAs) play critical regulatory roles in nasopharyngeal carcinoma (NPC)  pathogenesis. Family with sequence similarity 225 member B (FAM225B) is a novel lncRNA that has been implicated in several human cancers, yet its role in the context of NPC remains largely unclear. The aim of this study was to determine the expression level of FAM225B and its clinical significance in NPC patients. We observed a remarkable increase of FAM225B in NPC tissues and cell lines compared with controls. Also, highly expressed FAM225B was closely correlated with advanced TNM stage, distant metastasis, and poor overall survival. Interestingly, loss-of-function analysis revealed that FAM225B knockdown significantly inhibited tumor growth in vitro and in vivo, and decreased the migratory and invasive capacity of NPC cells. Mechanically, FAM225B functioned as an endogenous sponge by competing for miR-613 binding to up-regulate CCND2 expression. More importantly, rescue experiments further demonstrated that the suppressive impacts of FAM225B knockdown on cell proliferation, migration and invasion were significantly reversed after CCND2 overexpression. Taken all together, these findings highlight FAM225B as an oncogene that promotes NPC proliferation and metastasis through miR-613/CCND2 axis.
My new protocol v1
Authors: Frolova Monika
Published: June 2021

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Integration of a cargo brick v1
Authors: Carolyn N Bayer not provided , Rennig Maja , Ehrmann Anja , Norholm Morten
Published: June 2021

SEGA, the Standardized Genome Engineering Architecture, is a comprehensive strain collection that enables genome engineering by combining only two reagents: a DNA fragment that can be ordered from a commercial vendor and a stock solution of bacterial cells followed by incubation on agar plates. Recombinant genomes are identified by visual inspection using green-white colony screening akin to classical blue-white screening for recombinant plasmids. The modular nature of SEGA allows precise multi-level control of transcriptional, translational, and post-translational regulation. The SEGA architecture simultaneously supports increased standardization of genetic designs and a broad application range by utilizing well-characterized parts optimized for robust performance in the context of the bacterial genome This protocol describes the process of integrating a SEGA cargo brick. A cargo brick is integrated using tetA counterselection. This protocol also applies to integration of other bricks using tetA counterselection, e.g. splitting tetA.
Integration of a control brick v1
Authors: Carolyn N Bayer not provided , Rennig Maja , Ehrmann Anja , Norholm Morten
Published: June 2021

SEGA, the Standardized Genome Engineering Architecture, is a comprehensive strain collection that enables genome engineering by combining only two reagents: a DNA fragment that can be ordered from a commercial vendor and a stock solution of bacterial cells followed by incubation on agar plates. Recombinant genomes are identified by visual inspection using green-white colony screening akin to classical blue-white screening for recombinant plasmids. The modular nature of SEGA allows precise multi-level control of transcriptional, translational, and post-translational regulation. The SEGA architecture simultaneously supports increased standardization of genetic designs and a broad application range by utilizing well-characterized parts optimized for robust performance in the context of the bacterial genome This protocol describes to process of integrating a SEGA control brick. A control brick is integrated using galK counterselection.
Microfluidic Chip Production v1.1 v2
Authors: De Rop Florian , Aerts Stein , Poovathingal Suresh
Published: June 2021

Protocol for producing microfluidic chips used in HyDrop experiment.
Peculiarities of Children’s Imitation of Media Рersons in Parasocial Relations
Authors: Chaplinskaya Iuliia
Published: June 2021

In the modern world popular media personalities are becoming the role models for teenagers. Adolescents build parasocial relationships with them and then try to imitate the stale behavior of those media personalities. We do not know for sure which media personalities modern children choose to follow. We also do not know exactly how imitation takes place in parasocial relationships. That is why we set ourselves the goal to investigate the implementation of the mechanism of imitation in parasocial relations of Ukrainian high school students.
In November-December 2020, we surveyed 170 people from 11 regions of Ukraine according to the author’s questionnaire "Mechanisms of Parasociality" (Chaplinska-Naidenova). The study raised the question of the formation and functioning of parasocial relations. This article presents its results related to the manifestation of the mechanism of imitation at the level of frequency analysis.
First of all, we found that the most popular types of media people among young people are musicians (31.8 %), bloggers (26.5 %), actors (11.8 %), cartoon characters (5.9 %) and heroes of the series (2.9 %). Secondly, we can state the fact that adolescents do choose the media persona as a role model (64.7 %). Third, imitation can be individual or collective (group). Lastly, the parasocial imitation is based on the child’s desire not only to self-identify, but also to take a status position in the reference group through demonstrations of behavior patterns of a successful model (media personalities).
We see the limitations of our study in the fact that issues related to imitation are purely assertive and external in nature and do not reflect differences in the internal experiences or values of respondents under the influence of parasocial relations. We see further perspectives in the study of illusory mechanisms of parasociality.
The effect of Euribor on banking profitability: evidence from the Spanish banking system
Authors: Boto-García David , Álvarez Antonio , Baños Pino José Francisco
Published: June 2021

This paper studies the relationship between the Euribor rate and the return on average assets (ROAA) of the Spanish banking sector. We use quarterly time series data for the period 1995-2016. Our analysis also controls for bank factors, market concentration, the macroeconomic environment and time effects. The main purpose is to examine how the sector's ROAA varies with the slope of the yield curve. We find evidence of an inverse relationship between the Euribor rate and profitability. We also show that banking profitability is pro-cyclical and is positively related to the stock of performing loans and the national 10-year bond yield.
The Biological Effectiveness and Medical Significance of Far Infrared Radiation (FIR)
Authors: Lin Li-Chi , Lin Yi-Ying
Published: June 2021

The electromagnetic waves constitute different wavelengths of light from which Far infrared (FIR) is beneficial for living cells. Extensive studies and trials have been conducted over the last two decades in multidimensional biological domains to identify its unlimited health benefits. FIR radiations improve the microcirculation of the human body, stimulate cell growth, penetrate through skin tissues non-invasively, create intramolecular vibrations create an overall healthy metabolism, which ultimately affects overall improved cardiac and metabolic activity. This phenomenon is used to explore different pathological conditions to identify their significance in the medical field. In this review, we explored the biological effectiveness and the medical significance of Far infrared radiation (FIR) in murine melanoma Cell Growth, Lymphedema, airborne viruses, Cardiac diseases, Wound healing and burns, Autonomic Activities, Hemodialysis, Allergic Rhinitis, Aesthetic medicine, textiles, and other domains such as obesity and gut microbiota.
Percepción empresarial de la pandemia por COVID-19 y su impacto en el turismo: un análisis cualitativo del destino Extremadura, España
Authors: Sánchez-Rivero Marcelino , Rodríguez-Rangel María Cristina , Ricci-Risquete Alejandro
Published: June 2021

La pandemia de la COVID-19 ha provocado importantes perturbaciones en el sector turístico. Esta situación ha obligado a los agentes sectoriales a adoptar importantes medidas, pero también ha generado nuevas oportunidades de negocio. A partir de herramientas de análisis cualitativo, este trabajo analizó la percepción de los empresarios del sector sobre la pandemia por COVID-19 y esbozó las medidas que se deben adoptar para ayudar a la recuperación del sector en Extremadura, un destino turístico emergente de interior en el suroeste de España. Los resultados muestran que la principal preocupación de los empresarios es el impacto económico que la crisis está teniendo en sus negocios, además de las principales medidas que los empresarios turísticos solicitan para superar esta situación.
Virus Corona (SARS-CoV-2) penyebab COVID-19 kini telah bermutasi
Authors: Parwanto Edy
Published: June 2021

Telah dikemukakan bahwa virus corona menjadi penyebab COVID-19.(1) Virus corona yang dimaksud yaitu SARS-CoV-2, sedangkan COVID-19 kependekan dari corona virus disease-19. COVID-19 adalah penyakit yang disebabkan oleh SARS-CoV2 yang muncul awal Desember tahun 2019 di Wuhan, China. Sifat virus corona tersebut mudah menginfeksi manusia dan mudah menyebar hampir keseluruh penjuru dunia. Oleh karena itu terjadilah wabah (pandemi) COVID-19.

Seiring berjalannya waktu, virus corona mengalami mutasi gen. Mutasi gen merupakan perubahan gen secara spontan dan bersifat turun menurun dari partikel virus induk ke partikel virus anakannya. Kita mengetahui bahwa gen virus corona terusun atas rangkaian ribo nucleic acid  (RNA), oleh karena itu virus corona digolongkan sebagai virus RNA. Rangkaian gen pada virus corona tersebut menyusun genom virus corona. Genom virus corona mengandung 29 903 nukleotida (nt). Komponen genom virus corona yaitu 5’ untranslated region (5‘ UTR), rangkaian gen virus corona pengkode protein dan  3’ untranslated region (3’ UTR). Bagian 5’ UTR  terdapat pada up stream (pangkal) sedangkan 3’ UTR terdapat di bagian down stream (ujung), keduanya tidak mengkode protein. Secara berurutan dari arah up stream ke down stream, rangkaian gen virus corona terdiri atas gen ORF 1ab, gen S, gen ORF 3a, gen E, gen M, gen ORF 6, gen ORF 7a, gen ORF 7b, gen ORF 8, gen N, gen ORF 10.(2)
TERRA DOS MORTOS, LUGAR DOS VIVOS: O CEMITÉRIO SANTANA COMO PATRIMÔNIO CULTURAL DA CIDADE DE GOIÂNIA (GO)
Authors: Carvalho Daniele Roberta Oliveira de , Rodrigues Ruber P. A. , Silva Mary Anne Vieira
Published: June 2021

A partir da ampliação do conceito de patrimônio ocorrido a parir da segunda metade do século XX, o presente artigo pretende investigar quando e como os cemitérios foram incluídos no rol de bens culturais passiveis de patrimonialização. Para tanto, recorremos à História da cultura Material como norteador teórico-metodológico e às Cartas Patrimoniais como suporte documental para a presente análise. O Cemitério Santana na cidade de Goiânia (GO) é o lócus escolhido para abordarmos aspectos inerentes às perspectivas que foram salutares para a entrada dos cemitérios na lista do patrimônio histórico cultural – sobretudo a memória e a estética. Do ponto de vista da análise estética, buscamos nos postulados dos filósofos Longino, Edmund Burke e Immanuel Kant a ideia de sublime aplicada na interpretação da arte tumular do referido cemitério.
O EXPRESSIONISMO E O ESPÍRITO DE SUA ÉPOCA
Authors: Teixeira Eduardo De Souza , De Camargo Robson Corrêa
Published: June 2021

Este ensaio tem por objetivo considerar a vertente artística conhecida como Expressionismo, que teve seu auge do final do século XIX ao início do século XX, enquanto portadora do espírito de sua época. Para tal fim, apoia-se na Psicologia Analítica de Carl Gustav Jung (1875-1961), com o intuito de perceber elementos arquetípicos nas obras de arte da vanguarda expressionista.
A MEMÓRIA NOS GUIA: TRAJETOS E TREJEITOS DE UMA FESTA RELIGIOSA NO POVOADO DO BACALHAU – GOIÁS
Authors: Quadros Eduardo , Barbosa Raquel Miranda
Published: June 2021

Este artigo aborda uma festa religiosa dedicada a Nossa Senhora da Guia, que perpassa gerações em um pequeno povoado chamado Bacalhau, distrito da Cidade de Goiás. O texto situa as práticas devocionais mantidas pelos leigos e leigas, os usos e interesses da devoção, mesmo quando o templo católico do local estava em ruínas. Demonstra-se, com o cruzamento das fontes, que o festejo forneceu uma identidade ao povoado, ainda não reconhecida pelas políticas patrimoniais em curso na antiga capital goiana.
LINGUAGEM, APRENDIZAGEM E ENSINAMENTO NA PRÉ-HISTÓRIA MÍTICA DE A GUERRA DO FOGO (1981)
Authors: Silva Ademir Luiz da
Published: June 2021

Nesse artigo analisaremos de que forma a questão do ensino e da aprendizagem se dava no período pré-histórico, conforme representado no filme A Guerra do Fogo, lançado em 1981, com direção de Jean-Jacques Annaud. A partir de uma narrativa de aventura, com nítida relação com o mito grego de Prometeu, refletiremos sobre a importância da linguagem e da comunicação para transmissão de conhecimentos, num período marcado pela existência de grupos humanos em etapas de desenvolvimento simultâneas, porém diferenciadas.
A MEMÓRIA SOCIAL ATRAVÉS DO JORNAL FUNDINHO CULTURAL: CRÔNICAS DA CIDADE DE UBERLÂNDIA
Authors: Viana Nildo , Junqueira Ivanilda
Published: June 2021

A memória social se manifesta sob múltiplas formas, oferecendo ao pesquisador diversas possibilidades de recuperação da mesma. A partir da contribuição dos autores que desenvolveram reflexões teóricas sobre memória social, buscamos, no presente artigo, compreender as recordações do bairro Fundinho e da cidade de Uberlândia através do material publicado, especialmente as crônicas, no Jornal Fundinho Cultural. A partir da análise pudemos compreender a relação entre o processo de modernização e a constituição de “lugares de memória”, dentre os quais, alguns permanecem na paisagem urbana da cidade. A luta pela memória se manifesta sob diversas formas e a análise empreendida permitiu perceber algumas de suas principais formas de manifestação. Uma dessas formas é a existente entre o processo de modernização e a resistência revelando uma luta cultural tendo como palco o espaço urbano, o lugar de reprodução da vida cotidiana e suas recordações.
PAISAGEM NA ARTE: ANOTAÇÕES SOBRE A ESTÉTICA DA NATUREZA EM GOETHE E CARUS
Authors: Arraes Esdras Araujo
Published: June 2021

Reflete-se sobre a articulação entre a ideia de natureza e a representação da paisagem, em literatura e pintura, no período entre a segunda metade do século XVIII e as primeiras décadas do Oitocentos. Considera-se inicialmente o tratamento literário da paisagem feita pelo poeta alemão Johann Wolfgang von Goethe, com foco em seu romance epistolar Os sofrimentos do jovem Werther. A seguir, aborda-se o entendimento de Carl Gustav Carus sobre a paisagem e natureza apresentado em seu opúsculo Briefe über Landschaftsmalerei (“Cartas sobre pintura de paisagem”). Percebe-se que em ambos os casos, a apreensão sensível da natureza se dá por formas estéticas e científicas.
MEMÓRIAS E HISTÓRIAS SOBRE O DESENVOLVIMENTO DO COMÉRCIO DA VILA OPERÁRIA EM GOIÂNIA
Authors: Porto Alline Vieira
Published: June 2021

O presente artigo apresenta uma construção historiográfica sobre o desenvolvimento comercial da Vila Operária em Goiânia. Buscamos estabelecer a relação entre memória e história, dando enfoque às narrativas e representações dos moradores sobre a principal avenida do bairro, a Avenida Bernardo Sayão. Metodologicamente, utilizamos a História Oral como fonte primordial para o resgate da memória urbana local, partindo do uso de narrativas compartilhadas por moradores antigos e comerciantes locais. As narrativas possibilitaram estabelecer práticas sociais e identidades construídas nesse local, que permitiram descrever a formação e consolidação do comércio do bairro, e apreender um pouco da história de Goiânia.
O PROCESSO DE MODERNIZAÇÃO NO BAIRRO DE SANTO ANTÔNIO NA PRIMEIRA METADE DO SÉCULO XX: O CASO DA PRAÇA DA INDEPENDÊNCIA
Authors: Barros Gleicielly , Alves de Albuquerque Mariana Zerbone
Published: June 2021

Metodologicamente pautado na História Urbana, este artigo busca analisar os processos de mudança empreendidos na malha urbana do Bairro de Santo Antônio, tomando a longeva Praça da Independência, conhecida por Pracinha do Diário, como referencial principal. São analisadas, a partir desta, as reformas modernizantes, realizadas na primeira metade do século XX, com ênfase na década de 1930; bem como as tensões decorrentes do convívio com a modernidade, que pairava na cidade do Recife dos anos 1900-50; e o processo de gentrificação no período demarcado.
CONTABILIDADE REGULATÓRIA VERSUS CONTABILIDADE SOCIETÁRIA: UM ESTUDO DO NÍVEL DE COMPARABILIDADE NAS DISTRIBUIDORAS ASSOCIADAS À ABRADEE
Authors: Monteiro José Augusto De Medeiros , Almeida Fábia Araújo de , Carvalho Esdras Dos Santos
Published: June 2021

Este estudo teve como objetivo verificar se existem diferenças estatisticamente significantes e qual o nível de comparabilidade entre os valores contábeis regulatórios e societários divulgados pelas companhias de distribuição de energia elétrica. A amostra estudada foi formada por 38 das 41 distribuidoras associadas à Associação Brasileira de Distribuidores de Energia Elétrica (ABRADEE), responsáveis por fornecerem energia elétrica a 99,6% dos consumidores brasileiros no ano de 2019. Para a análise estatística inferencial, realizou-se o teste de comparabilidade para amostras emparelhadas de Wilcoxon, considerando um nível de significância de 1% e, objetivando verificar o nível de comparabilidade, utilizou-se o índice de comparabilidade de Gray (1980). Os resultados indicaram que apenas o Patrimônio Líquido não apresenta diferenças estatisticamente significantes e, além disso, o nível de comparabilidade entre as duas contabilidades é muito baixo, considerando a média, ocorreram apenas 3 casos materialmente comparáveis. Verificou-se que, na média, os números regulatórios referentes às variáveis ativo, passivo e patrimônio líquido superaram os valores societários correspondentes. O lucro líquido, por sua vez, foi a única variável a exibir resultados societários superiores aos valores regulatórios. Para essa variável, a maior parte das companhias estudadas revelou valores contábeis societários 15% maiores ou menores que os regulatórios durante o período estudado. A materialidade das divergências encontradas revela um problema para os usuários da informação contábil do setor elétrico, que podem ser induzidos a tomar decisões divergentes de acordo com o conjunto de informação contábil consultado.