bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of neutron scattering kernels for cold neutron reflector materials
Authors: Granada José Rolando , Márquez Damián José Ignacio , Dawidowski Javier , Robledo José Ignacio , Helman Christian , Romanelli Giovanni , Škoro Goran
Published: September 2021

The newest neutron scattering applications are highly intensity-limited techniques that demand reducing the neutron losses between source and detectors. In addition, the nuclear industry demands more accurate data and procedures for the design and optimization of advanced fission reactors, especially for the treatment of fuel and moderator materials. To meet these demands, it is necessary to improve the existing calculation tools, through the generation of better models that describe the interaction of neutrons with the systems of interest. The Neutron Physics Department at Centro Atomico Bariloche (CNEA, Argentina) has been developing over the time new models for the interaction of slow neutrons with materials, to produce scattering kernels and cross section data in the thermal and cold neutron energy region. Besides the studies carried out on neutron moderators, we have recently begun looking at materials that could serve as efficient neutron reflectors over those energy ranges. In this work we present the results of transmission and scattering experiments on diamond nanopowder and magnesium hydride, carried out simultaneously at the VESUVIO spectrometer (ISIS, UK), and compare them with newly generated cross-section libraries.
Relationship between dynamic foot-ground contact area and balance impairments in adolescents with down syndrome
Authors: Khallaf Mohamed E. , Fayed Eman , Sweif Radwa E. , Alsalem Abdulkarem
Published: September 2021

PURPOSE: Down Syndrome (DS) is characterized by intellectual disability, hypotonia, and joint laxity. Physical disability can be an additional problem and manifests as reduced lower limb muscle strength and impaired balance. The objectives of this study were to characterize DS dynamic foot-ground contact area and to study its relationship with balance impairment among adolescents with DS. METHODS: Twenty-eight children and adolescents with DS and 28 non-DS adolescents/children were matched for age and sex. The Oxford Ankle Foot Questionnaire (parents’ version) was used to measure disability related to ankle/foot problems in all subjects. A pressure-sensitive mat was used to assess the contact area and arch index. Also, a Biodex balance system was used for measuring postural stability. RESULTS: There were significant differences between both groups in all domains of the Oxford Ankle Foot Questionnaire, overall contact area, and arch index (p < 0.05). Overall postural stability index was significantly decreased in subjects with DS (p < 0.05). There was a nonsignificant correlation between contact area and postural stability (p > 0.05). CONCLUSION: Adolescents with DS exhibited larger mid-foot and forefoot contact areas with respect to non-DS matched children. Impairment of balance in adolescents with DS is a multifactorial problem not related to changes in the foot contact area.
Imputing missings in official statistics for general tasks – our vote for distributional accuracy
Authors: Thurow Maria , Dumpert Florian , Ramosaj Burim , Pauly Markus
Published: September 2021

In statistical survey analysis, (partial) non-responders are integral elements during data acquisition. Treating missing values during data preparation and data analysis is therefore a non-trivial underpinning. Focusing on the German Structure of Earnings data from the Federal Statistical Office of Germany (DESTATIS), we investigate various imputation methods regarding their imputation accuracy and its impact on parameter estimates in the analysis phase after imputation. Since imputation accuracy measures are not uniquely determined in theory and practice, we study different measures for assessing imputation accuracy: Beyond the most common measures, the normalized-root mean squared error (NRMSE) and the proportion of false classification (PFC), we put a special focus on (distribution) distance measures for assessing imputation accuracy. The aim is to deliver guidelines for correctly assessing distributional accuracy after imputation and the potential effect on parameter estimates such as the mean gross income. Our empirical findings indicate a discrepancy between the NRMSE resp. PFC and distance measures. While the latter measure distributional similarities, NRMSE and PFC focus on data reproducibility. We realize that a low NRMSE or PFC is in general not accompanied by lower distributional discrepancies. However, distributional based measures correspond with more accurate parameter estimates such as mean gross income under the (multiple) imputation scheme.
A reference framework for health and safety in the workplace in China and the European Union: A comparative study
Authors: Zhang HanYuan , Yang Xue , Martínez-Aires Ma Dolores
Published: September 2021

BACKGROUND: Occupational Health and Safety (OHS) has a direct repercussion on the work, social and economic environments. The regulatory frameworks developed by each country are a basic aspect of OHS action policies. OBJECTIVE: This study analyses and compares the differences in OHS regulations in China and the European Union (EU) to identify weaknesses or gaps in the Chinese regulations. METHODS: Firstly, an overview of the OHS situation in the EU and China is carried out to provide context. Following this, a comparison of OHS regulations is conducted by searching different European and Chinese databases. The comparison focuses on several areas: socio-economic issues, accident rates, and the OHS regulatory framework. RESULTS: Since 1989, the EU has produced a broad and comprehensive OHS regulatory framework. Almost 30 years later, its positive impact can be seen in EU accident rates, indicating that this framework might be used as a reference for other territories or countries. China has a complicated system with over 280 OHS legislative regulations, in the form of laws, regulations, rules, integrated regulations, etc. that lead to a mixture and repetition of contents. CONCLUSIONS: The Chinese OHS legislation is still being constructed and complemented, since the two main Chinese OHS laws were approved during the last decade. This contrasts with the mature European framework, as it has been modified and completed over the years.
PERSEPSI, SIKAP DAN PERILAKU MASYARAKAT TERHADAP PROGRAM 3 M DALAM MENGHINDARI PERSEBARAN COVID-19 (Studi kasus Masyarakat Desa Sutawinangun Kecamatan Kedawung Kabupaten Cirebon)
Authors: . Somantri , Al Ghozali Muhammad Iqbal
Published: September 2021

Pandemi Covid-19 dengan eksistensitas tinggi dan penyebarannya signifikan mengharuskan adanya upaya memutus matarantai sebarannya diantaranya dengan 3M (mencuci tangan, memakai masker dan menjaga jarak). Aspek yang dikaji adalah; persepsi, sikap dan perilaku masyarakat terhadap pelaksanaan program 3M dalam menghindari persebaran covid-19 di Desa Sutawinangun Kecamatan Kedawung Kabupaten Cirebon. Penelitian kualitatif dipilih sebagai metode untuk mengekplorasi dan memahami makna yang dianggap berasal dari masalah sosial atau kemanusian, berfokus pada makna individual, dan menerjemahkan komplesitas suatu persoalan. Data deskriptif dikembangkan dari hasil perolehan sejumlah informasi tertulis maupun lisan dari hasil pengamatan. Setelah adanya anggota masyarakat yang terpapar dan dinyatakan zona merah covid-19, kemudian ada rencana relokasi penderita covid di Sutawinangun baru tumbuh kesadaran melaksanakan 3M. Bagaimana agar masyarakat terbuka dan siap bekerjasama pada upaya mempercepat penanganan dan pencegahan virus corona untuk kembali merasakan situasi kondusif. Upaya menyelesaikan pandemi ini mutlak diperlukan dengan 3M dan #dirumahaja dibarengi tindakan kongkret untuk melakukan aktivitas di rumah dalam menjaga kesehatan. Solidaritas masyarakat menjadi faktor penting sebagai modal sosial untuk melawan Covid-19. Masyarakat berfokus menerapkan 3M, pola hidup bersih dan sehat serta mengurangi mobilitas kerumunan dalam masyarakat untuk terhindar dari virus tersebut
Authors: Widyastuti Aviani , Arisanti Ike , Harventy Gina
Published: September 2021

Until now, many schools, especially elementary schools, do not understand how to carry out school financial administration in accordance with Permendagri Regulation 55 of 2008 concerning Procedures for Administration and Preparation of Accountability Reports as well as the Treasurer's budget and tax reporting. One of them is SD Muhammadiyah 4 Batu which is an elementary school that serves basic education teaching and is located in Batu City. The principal of the Muhammadiyah Elementary School in Batu City said that so far the school treasurer had difficulties in preparing the budget. Based on the statement expressed by the principal of SD Muhammadiyah 4 Kota Batu, in order to improve the ability in budgeting, it is deemed necessary to conduct training and assistance in budgeting at SD Muhammadiyah 4 Kota Batu so that the realization of activities can run smoothly. The approach method used is training and mentoring. Direct mentoring activities were carried out at SD Muhammadiyah 4 Batu City. The implementation of the assistance will be continued in the future by looking at the progress report on the financial reports that have been prepared by partners.
Yearning for Tawhid: Three Muslims’ Journeys in Justice Work in the Settler Colonial Context of Toronto
Authors: Ahmed Farah
Published: September 2021

This critical narrative study seeks to explore two central research questions: 1) How do
Muslim peoples understand, approach and engage in social justice work in and around Toronto
and what are their experiences, and 2) What are the ways in which Islam and spirituality
influence, impact and shape their social justice work? Using a lens that involves critical race
theory, anti-colonialism and Islam, I delve deep into my own experiences and perspectives on
Islam, spirituality and social justice work, as well as those of two other Muslim social justice
advocates involved in Indigenous sovereignty, Black liberation and anti-Islamophobia
movements. The findings of this study offer deep critical insights on the state of anti-oppressive
and transformative social work and social justice spaces in the settler colonial context of
Toronto. Central concepts explored in this work include dynamics of anger, significant
relationships and Islamic concepts such as tawhid. It has been completed as partial completion of
the Master of Social Work Program at Ryerson University.
Shear Strength Prediction of FRP-reinforced Concrete Beams Using an Extreme Gradient Boosting Framework
Authors: Kaveh Ali , Dadras Eslamlou Armin , Mahdipour Moghani Roya
Published: September 2021

Despite the importance and accuracy of empirical models, most of the existing models are only accurate on the collected experimental data. Adding new data, or even considering noise or variance in the data leads to loss of model accuracy. The objective of this paper is to alleviate overfitting and develop a more accurate and reliable alternative method using a decision-tree-based ensemble Machine Learning algorithm that uses a gradient boosting framework for the prediction of the ultimate shear strength of FRP-reinforced concrete beams without stirrups. To enhance the robustness of the results, make full use of training samples (without the validation set), and alleviate the randomness in selecting test samples, the K-Fold Cross Validation method is employed. Using a dataset including 205 samples, results show that the extreme gradient boosting framework (XGBoost) providing better prediction. In fact, XGBoost results have higher precision and higher generalization in comparison with the empirical equations, the current design codes of practice, Least Absolute Shrinkage and Selection Operator model (LASSO), and Random Forest model (RF).
ОГЛЯД УКРАЇНОМОВНОГО ПЕРЕКЛАДУ МОНОГРАФІЇ АДАМА ДЖОНСА. ГЕНОЦИД: ВСТУП ДО ГЛОБАЛЬНОЇ ІСТОРІЇ. КИЇВ: ДУХ І ЛІТЕРА, 2020. 696 с.
Authors: Ponomarov Vitalii
Published: September 2021

Книга є своєрідною спробою узагальнення сучасних знань про причини геноциду, його природу, методи та мотиви виконавців.
ЇЖА, ГРОШІ ТА БАРТЕР У ЛЬВІВСЬКОМУ ГЕТТО, СХІДНА ГАЛИЧИНА
Authors: Aleksiun Natalia
Published: September 2021

Ця стаття базується на дослідженні авторкою повсякденного життя у схованці євреїв Східної Галичини за часів німецької окупації.
THE EXPANSION THERMOMETER IN PRESCHOOLERS’ THINKING
Authors: Kampeza Maria , Vellopoulou Angeliki , Fragkiadaki Glykeria , Ravanis Konstantinos
Published: September 2021

Children form representations of concepts, physical phenomena and technical objects which are critical to teaching and learning. In addition, they are familiar with the everyday usefulness of many particular objects, although it is not certain that they associate them with the scientific aspects of their function. In this research, preschoolers’ representations of the expansion thermometer were explored, as well as their ability to distinguish it as a specialized technical tool. The sample consisted of 111 children (53 boys and 58 girls) aged 5-6 years from 9 public kindergartens in Patras, Greece and data were collected through semi-structured individual interviews. The results demonstrated that although some children replied in a satisfactory way to all interview questions, the majority of the children were not able to distinguish the thermometer as a particular object and struggled with its function, so the suggestion for it to be used in curricula and/or educational activity books should be made cautiously. Key words: preschoolers’ representations, expansion thermometer, preschool education, science and technology education.
IMPLEMENTASI TRANSFER LEARNING PADA CONVOLUTIONAL NEURAL NETWORK UNTUK DIAGNOSIS COVID-19 DAN PNEUMONIA PADA CITRA X-RAY
Authors: Wijaya Alexander Eric , Swastika Windra , Kelana Oesman Hendra
Published: September 2021

COVID-19 menjadi salah satu masalah yang besar bagi banyak negara di dunia sejak tahun 2020. COVID-19 dan Pneumonia memiliki kemiripan dalam hal gejala seperti batuk dan sesak napas. Upaya diagnosis COVID-19 dan Pneumonia dilakukan dengan pemeriksaan laboratorium dan juga rontgen dada. Citra hasil x-ray dada pasien COVID-19 memiliki kesamaan dengan hasil x-ray pasien Pneumonia tetapi ahli radiologi berhasil menemukan bahwa terdapat perbedaan antara citra x-ray dada penderita COVID-19 dengan citra x-ray dada pasien Pneumonia dimana terdapat pola seperti kaca yang ditumbuk pada hasil citra X-ray penderita virus Corona.Diagnosis pada citra x-ray dada pasien menggunakan model Deep Learning. Pada penelitian ini juga akan membandingkan performa model Xception menggunakan Transfer Learning dengan performa model Xception tanpa Transfer Learning. Terdapat 4 eksperimen konfigurasi pada model Xception tanpa Transfer yaitu konfigurasi pelatihan layer base model, pelatihan base model, pelatihan custom head model, dan pelatihan pada layer base model serta custom head model. Terdapat 2 eksperimen menggunakan model Resnet50 dan VGG16 tanpa Transfer Learning. Model Xception menggunakan Transfer Learning memiliki performa lebih baik daripada model Xception tanpa Transfer Learning. Keempat eksperimen model Xception tanpa Transfer Learning dan kedua eksperimen dengan model Resnet serta VGG16 memiliki akurasi diatas 85%. Namun keenam model tanpa Transfer Learning tersebut tidak mampu mengenali Pneumonia pada citra x-ray dada pasien.
Bellagio II Report: Terrestrial Applications of Space Medicine Research
Authors: Sides Marian B. , Johnston Smith L. , Sirek Adam , Lee Peter H. , Blue Rebecca S. , Antonsen Eric L. , Basner Mathias , Douglas Grace L. , Epstein Ari , Flynn-Evans Erin E. , Gallagher Michael B. , Hayes Judith , Lee Stuart M. C. , Lockley Steven W. , Monseur Brent , Nelson Nicolas G. , Sargsyan Ashot , Smith Scott M. , Stenger Michael B. , Stepanek Jan , Zwart Sara R.
Published: September 2021

AbstractINTRODUCTION: For over 50 yr, investigators have studied the physiological adaptations of the human system during short- and long-duration spaceflight exposures. Much of the knowledge gained in developing health countermeasures for astronauts onboard the International
Space Station demonstrate terrestrial applications. To date, a systematic process for translating these space applications to terrestrial human health has yet to be defined.METHODS: In the summer of 2017, a team of 38 international scientists launched the Bellagio ll Summit Initiative.
The goals of the Summit were: 1) To identify space medicine findings and countermeasures with highest probability for future terrestrial applications; and 2) To develop a roadmap for translation of these countermeasures to future terrestrial application. The team reviewed public domain literature,
NASA databases, and evidence books within the framework of the five-stage National Institutes of Health (NIH) translation science model, and the NASA two-stage translation model. Teams then analyzed and discussed interdisciplinary findings to determine the most significant evidence-based countermeasures
sufficiently developed for terrestrial application.RESULTS: Teams identified published human spaceflight research and applied translational science models to define mature products for terrestrial clinical practice.CONCLUSIONS: The Bellagio ll Summit identified a snapshot
of space medicine research and mature science with the highest probability of translation and developed a Roadmap of terrestrial application from space medicine-derived countermeasures. These evidence-based findings can provide guidance regarding the terrestrial applications of best practices,
countermeasures, and clinical protocols currently used in spaceflight.Sides MB, Johnston SL III, Sirek A, Lee PH, Blue RS, Antonsen EL, Basner M, Douglas GL, Epstein A, Flynn-Evans EE, Gallagher MB, Hayes J, Lee SMC, Lockley SW, Monseur B, Nelson NG, Sargsyan A, Smith SM, Stenger MB,
Stepanek J, Zwart SR; Bellagio II Team. Bellagio II report: terrestrial applications of space medicine research. Aerosp Med Hum Perform. 2021; 92(8):650669.
IMPROVING TEACHERS' CREATIVITY IN TEACHING DURING THE COVID-19 PANDEMIC THROUGH ASSIGNMENT METHODS IN SLB NEGERI PEMBINA PEKANBARU
Authors: Yasni Yasni
Published: September 2021

Based on the results of pre-research observations conducted by researchers on Monday at Pembina State SLB Pekanbaru, problems were found, namely: There are still teachers who have not been able to apply online learning at home due to limitations in technology. There are still many teachers who apply the learning model with many assignments without paying attention to the situation and conditions during this covid-19 outbreak. Learning is only monotonous and by using creative learning models that are fun and not boring for children, children's character and creativity must continue to be fostered. Giving too much material and tiring children makes children lose their appetite for learning. The type of research is school action research with a sample of 34 teachers at SLB Pembina Pekanbaru. Based on the results of the analysis and discussion, it can be concluded that the creativity of teachers in teaching at SLB Pembina Pekanbaru can be increased through the assignment method. Under these conditions, the level of teacher acceptance increases. Comparison of aspects of teacher creativity in teaching through the assignment method in cycle I and II increased from 58.8% and cycle II to 75.1%.
Townspeople and peasants in social structure Starodub regiment (1654–1781)
Authors: Khrolenok Evgeniy V.
Published: September 2021

The territory of the Starodub regiment is unique in historical terms. Being the center of the region of the Grand Duchy of Lithuania, it was one of its lands able to gain a foothold in the Getman Ukraine. At the same time, Starodubshchina is now the only part of the Hetman region that is part of the Russian Federation. Thus, the region has incorporated traditions, culture and legal customs of all three states, on the border of which it is now located. Despite the considerable interest in the history of the Starodub regiment as a whole, the social history of ordinary rural and urban residents remains poorly understood. The aim of this work is an attempt to illuminate the social situation of the pospolits: townspeople and peasants of the Starodubsky regiment from the moment the Cossack administration was established in the region in 1654 until the population of the region was subordinated to general imperial Russian standards. And also to reveal the characteristic differences of this region. The article was created on the basis of the analysis of various, including little-studied documents stored in the archives of Belarus, Ukraine and Russia, as well as the works of Russian and Ukrainian scientists. The process of establishing city self-government in Starodub and the formation in its midst of a unique elite – noble bourgeois is shown. Many representatives of this social group went through the process of evolution from urban dwellers to Cossack foreman and the subsequent Russian nobility over the indicated period. In addition, the social status of rural residents of the Starodub regiment is described. Which with the establishment of the Cossack administration received personal freedom, but by the end of the 18th century completely lost her. The examples of residents of specific settlements show the methods that the peasants resorted to trying to avoid dependence on large landowners, as well as the process of distinguishing between the pospolits and the Cossack class. At the same time, emphasis was placed on the characteristic differences in the social status of urban and rural residents of the Starodub regiment from other lands that were part of the Russian Empire. The totality of the facts revealed in this way reinforces the main thesis about the complexity and versatility of this Belarusian-Russian-Ukrainian region.
Penyuluhan Gizi Melalui Metode Emo Demo Untuk Mengubah Pengetahuan Kader Tentang Hipertensi
Authors: Nafilah Nafilah , Palupi Fitria Dhenok
Published: September 2021

Informasi yang kurang dan rendahnya pengetahuan mengenai hipertensi dapat menjadi salah satu penyebab hipertensi. Salah satu upaya yang dapat dilakukan untuk mengatasi hal tersebut adalah penyuluhan mengenai hipertensi. Penyuluhan ini bertujuan untuk meningkatkan pengetahuan dan kesadaran masyarakat mengenai alternatif pencegahan hipertensi. Penyuluhan dilakukan menggunakan metode ceramah, pembagian booklet, emo demo dengan 55 responden ibu PKKBD. Metode emo demo yang digunakan bertujuan agar informasi yang diberikan dapat lebih mempengaruhi emosi masyarakat. Emo demo yang diberikan berupa cara membuat sari tempe. Hasil penyuluhan menemukan adanya perbedaan signifikan skor pretest dan postest mengenai pengetahuan hipertensi setelah dilakukan penyuluhan menggunakan metode ceramah, pembagian booklet, dan emo demo. Hasil ini membuktikan bahwa penggunaan ketiga metode tersebut secara bersama - sama efektif dalam meningkatkan pengetahuan hipertensi. Ibu Kader yang mengikuti kegiatan juga ikut aktif dalam pelaksanaan kegiatan penyuluhan. Tim pengabdian masyarakat berharap agar pembuatan sari tempe melalui emo demo tersebut juga dapat disosialisasikan kembali oleh ibu PKKBD kepada masyarakat Desa Argorejo agar dapat diaplikasikan.
Optimasi Promosi Produk Menggunakan Media Sosial pada UMKM Binaan PKKP Kabupaten Blora
Authors: Irawan Candra , Rachmawanto Eko Hari , Susanto Ajib , Sari Christy Atika
Published: September 2021

Saat ini produk UMKM yang dihasilkan oleh kelompok usaha atau industry rumah tangga belum dikenal oleh calon pembeli atau pelanggan yang ada di luar daerahnya dikarenakan promosi yang dilakukan hanya dari cerita orang ke orang lain. Beberapa pelaku sudah menggunakan grup-grup di apalikasi chating, media sosial dan jejaring sosial akan tetapi hanya dilakukan tidak rutin dan belum menggunakan cara yang efektif dalam melakukan promosi dan penjualan. Kendala lain yang dihadapi adalah desain kemasan yang dibuat belum mencirikan produk yang dijual dan belum memberikan informasi yang detail tentang produknya sehingga mengurangi daya tarik pembeli. Tujuan dari program pengabdian ini adalah untuk memberikan pelatihan internet marketing dan design packaging untuk UMKM Binaan PKKP Kabupaten Blora sehingga dapat membuat desain kemasan dan melakukan pemasaran online melalui media sosial dan jejaring sosial.
Peningkatan Kesadaran Masyarakat Terhadap Penyakit Hipertensi dan Gout di Kelurahan Pakuan Baru
Authors: Sutrisno Deny , Okmadini Rena
Published: September 2021

Penyakit tidak menular (PTM) merupakan penyakit yang bersifat kronis dan tidak ditularkan dari orang keorang. PTM terus mengalami peningkatan seiring dengan perubahan pola hidup masyarakat kearah yang kurang seimbang. Faktor resiko PTM di Provinsi Jambi khususnya di RT. 22 Kelurahan Pakuan Baru Kecamatan Jambi Selatan antara lain Nasofaringitis Akut, Hipertensi dan Asam Urat. Hal tersebut disebabkan kurangnya pengetahuan dan kesadaran terhadap bahaya PTM yang menyebabkan deteksi dini. Hal ini juga disebabkan enggannya masyarakat memeriksakan diri selama sebelum merasa sakit. Masalah inilah yang menjadi dasar dilakukannya kegiatan pengabdian berupa pemeriksaan kesehatan secara gratis yang diselingi dengan diskusi seputar kesehatan, khusunya PTM dan kiat-kiat dalam pencegahannya.
PKM Pelatihan Optimasi Pendataan Santri Baru Dengan Framework YII pada Pondok Pesantren Askhabul Kahfi Gunungpati Polaman Kecamatan Mijen Kota Semarang
Authors: Novianto Sendi
Published: September 2021

Informasi saat ini berperan sangat penting sekali di berbagai bidang, baik dibidang perbankan, bisnis, maupun di bidang pendidikan. Pondok pesantren Askhabul Kahfi adalah lembaga pendidikan islam. Dalam pendataan para santrinya, pondok ini sudah menggunakan sistem informasi secara online. Tetapi pada penerapan pendataan santri-santri yang ada disana belum dilakukan secara optimal. Hal ini menyebabkan banyaknya data yang redudansi / duplikasi. Selain itu juga, efek dari data redudansi ini menyebabkan tidak updatenya data yang ada, hal ini menyebabkan informasi antara data yang redudansi menjadi tidak sinkron / tidak sama. Dengan terjadinya hal ini tentunya akan menyebabkan kebingungan bagi pihak yang berhubungan, misalnya informasi ukuran jas calon santri bisa berbeda saat pengukuran dan pembuatannya. Dari informasi yang didapatkan, hal ini karena sistem informasi yang dipakai adalah buatan dari pihak ketiga, hal ini menyulitkan mereka untuk mendapatkan data yang diinginkan sehingga, secara tidak langsung mereka mengkombinasikan data yang ada dengan data manual. Dengan adanya pengenalan framework dalam membangun sistem informasi, diharapkan mereka nantinya dapat mengelola dan mengembangkan sistem informasi yang sesuai dengan keinginan mereka sendiri secara mandiri dan tentunya juga menghindari adanya redudansi data. Dalam prakteknya, setelah mereka mengetahui fungsi dari framework dan komponen pendukung lainnya, mereka dengan mudah dapat membuat aplikasi sederhana untuk dikembangkan lebih lanjut ke aplikasi sistem informasi pendataan yang lebih komplek.
Membangun Etika Bisnis dalam Industri Pariwisata Melalui Program Pengabdian Masyarakat di Ketapanrame, Mojokerto, Jawa Timur
Authors: Pratono Aluisius Hery , Megawati Veni , Mulya Teguh Wijaya , Prima Delta A.
Published: September 2021

Artikel ini bertujuan untuk mengkaji upaya membangun etika bisnis dalam industri pariwisaya melalui program pengabdian masyarakat yang dilaksanakan di Desa Ketapanrame, Mojokerto Jawa Timur. Pelaksanaan program ini menggunakan beberapa pendekatan mulai dari workshop, studi banding, serta self-assessment yang melibatkan partisipasi warga masyarakat. Hasil kajian menunjukan keberhasilan upaya membangun etika bisnis dalam industri pariwisata ditentukan oleh dinamika organisasi pengelola unit usaha termasuk hubungannya dengan para pemangku kepentingan. Selain itu, munculnya wabah Covid-19 menunjukan bahwa lingkungan bisnis yang sangat dinamis sangat menentukan upaya membangun etika bisnis dalam industri pariwisata.
Edukasi Stop Merokok di dalam Rumah di Dusun Krandon, Kwaren, Kecamatan Ngawen, Kabupaten Klaten
Authors: Astuti Fardhiasih Dwi , Nugraheni Aulia Putri
Published: September 2021

Perilaku merokok menjadi salah satu permasalahan kesehatan yang serius. Indonesia menduduki peringkat ketiga dengan jumlah perokok terbanyak di dunia. Berdasarkan data riskesdas 2018 persentase perokok diatas 15 tahun sebanyak 33,8%.  Hasil survey Perilaku Hidup Bersih dan Sehat (PHBS) di Dusun Krandon, Kwaren, Ngawen, Klaten, khususnya indikator tidak merokok di dalam rumah pada masyarakat RT 02 diperoleh sebesar 57% responden yang merokok di dalam rumah. Persentase ini menunjukkan bahwa kesadaran untuk tidak merokok di dalam rumah masih rendah. Pegabdian ini bertujuan melakukan edukasi stop merokok didalam rumah. Metode yang digunakan dalam penngabdian ini adalah eduksi dengan penyuluhan dan pemasangan poster yang dilanjutkan dengan evaluasi. Berdasarkan kegiatan yang telah dilakukan didapatkan hasil bahwa masyarakat antusias dalam kegiatan. Hasil evaluasi masyarakat merasa kegiatan sangat bermanfaat dan dapat meningkatkan pengetahuan tentang bahaya merokok. Peggunaan poster dapat mengingtkan masyarakat untuk tidak merokok didalam rumah. Kegiatan ini merupakan salah satu upaya mengedukasi masyarakat tentang bahaya merokok dan menjadikan masyarakat berperilaku lebih baik dengan berhenti merokok. Kegiatan edukasi perlu ditingkatkan agar masyarakat lebih sehat.
Penggunaan Teknologi Tepat Guna Meja Colet Batik di Rumah Kreatif De Suket
Authors: Amalia Amalia , Tjahyono Rudy
Published: September 2021

Sebagian besar industri batik di Indonesia termasuk ke dalam unit usaha kecil dan menengah (UKM), sehingga membutuhkan peningkatan daya saing UKM melalui pengembangan alat bantu untuk mempermudah proses pembuatan batik. Salah satu proses pembuatan batik yang paling penting adalah pewarnaan. Pewarnaan dengan teknik colet merupakan salah satu teknik praktis, efisien dan memberikan daya tarik bagi produk Batik. Rumah Kreatif De Suket memiliki permasalahan dalam menjalankan usahanya, antara lain keterbatasan alat dalam proses pencoletan dan luas ruang yang sempit. Proses pencoletan dilakukan menggunakan gawangan batik atau terkadang hanya alakadarnya di lantai. Hal ini dapat menghambat produktivitas, serta postur atau posisi kerja yang salah dapat mengakibatkan cidera atau penyakit kerja. Rumah kreatif juga memiliki luas ruang yang sempit sehingga sulit menyimpan peralatan kerja, seperti meja colet yang tersedia di pasaran. Program kemitraan masyarakat ini bertujuan untuk menyelesaikan permasalahan yang dihadapi mitra antara lain mempermudah proses produksi terutama pada bagian pewarnaan dengan teknik colet, memiliki postur kerja yang baik, dan memudahkan penyimpanan pada stasiun kerja pencoletan.
Pendampingan Pembentukan Badan Usaha Milik Desa di Desa Tinting Boyok, Sekadau, Kalimantan Barat
Authors: Nova Kristianus , Arwanto Arwanto
Published: September 2021

Pembentukan Badan Usaha Milik Desa (BUMdes) adalah salah upaya yang ditempuh oleh seluruh perangkat desa untuk meningkatkan pendapatan dan pertumbuhan ekonomi desa. Pembangunan desa melalui pembentukan sarana dan pasarana tersebut dapat meningkatkan perekonomian yang kokoh. Pengamatan di lapangan menunjukkan bahwa BUMdes sangat diperlukan di Desa Tinting Boyok, Sekadau, Kalimantan Barat, mengingat Pendapatan Asli Desa (PADes) berjumlah Rp 0. Pembentukan BUMdes ini bertujuan untuk mendapatkan dana tambahan yang dapat digunakan untuk membantu pembiayaan pembangunan dan perekonomian desa mengingat Desa Tinting Boyok masih berkualifikasi sebagai desa tertinggal. Metode yang digunakan dalam kegiatan ini yaitu menganalisa potensi desa, sosialisasi dan koordinasi serta grup discussion. Beberapa tahapan yang dilaksanakan dalam kegiatan ini berupa pemetaan potensi, sosialisasi BUMDes dan pendampingan. Kegiatan ini mampu mendorong Pemerintah Desa Tinting Boyok meningkatkan pendapatan asli desa melalui pembentukan dan tata tata kelola BUMDes yang baik. BUMDes bergerak di bidang pengelola jual beli hasil panen kelapa sawit di lingkungan desa. Hal ini mengingat Desa Tinting Boyok merupakan pusat jual beli hasil panen kelapa sawit di Kabupaten Sekadau.
Single Entity Behavior of CdSe Quantum Dot Aggregates During Photoelectrochemical Detection
Authors: Subedi Pradeep , Parajuli Suman , Alpuche-Aviles Mario A.
Published: September 2021

We demonstrate that colloidal quantum dots of CdSe and CdSe/ZnS are detected during the photooxidation of MeOH, under broad spectrum illumination (250 mW/cm2). The stepwise photocurrent vs. time response corresponds to single entities adsorbing to the Pt electrode surface irreversibly. The adsorption/desorption of the QDs and the nature of the single entities is discussed. In suspensions, the QDs behave differently depending on the solvent used to suspend the materials. For MeOH, CdSe is not as stable as CdSe/ZnS under constant illumination. The photocurrent expected for single QDs is discussed. The value of the observed photocurrents, > 1 pA is due to the formation of agglomerates consistent with the collision frequency and suspension stability. The observed frequency of collisions for the stepwise photocurrents is smaller than the diffusion-limited cases expected for single QDs colliding with the electrode surface. Dynamic light scattering and scanning electron microscopy studies support the detection of aggregates. The results indicate that the ZnS layer on the CdSe/ZnS material facilitates the detection of single entities by increasing the stability of the nanomaterial. The rate of hole transfer from the QD aggregates to MeOH outcompetes the dissolution of the CdSe core under certain conditions of electron injection to the Pt electrode and in colloidal suspensions of CdSe/ZnS.
OsB9−: An Aromatic Osmium-Centered Monocyclic Boron Ring
Authors: Yu Rui , Pan Sudip , Cui Zhong-hua
Published: September 2021

Transition-metal-centered monocyclic boron wheels are important candidates in the family of planar hypercoordinate species that show intriguing structure, stability and bonding situation. Through the detailed potential energy surface explorations of MB9− (M = Fe, Ru, Os) clusters, we introduce herein OsB9− to be a new member in the transition-metal-centered borometallic molecular wheel gallery. Previously, FeB9− and RuB9− clusters were detected by photoelectron spectroscopy and the structures were reported to have singlet D9h symmetry. Our present results show that the global minimum for FeB9− has a molecular wheel-like structure in triplet spin state with Cs symmetry, whereas its heavier homologues are singlet molecular wheels with D9h symmetry. Chemical bonding analyses show that RuB9− and OsB9− display a similar type of electronic structure, where the dual σ + π aromaticity, originated from three delocalized σ bonds and three delocalized π bonds, accounts for highly stable borometallic molecular wheels.
The Influence of Infection by Different Leishmania (Viannia) braziliensis Isolates on the Pathogenesis of Disseminated Leishmaniasis
Authors: Oliveira Walker N. , Dórea Andreza S. , Carneiro Pedro P. , Nascimento Maurício T. , Carvalho Lucas P. , Machado Paulo R. L. , Schriefer Albert , Bacellar Olívia , Carvalho Edgar M.
Published: September 2021

Disseminated Leishmaniasis (DL) is an emerging and severe form ofLeishmania (Viannia) braziliensisinfection defined by the presence of 10 and up to more than 1,000 skin lesions. The mechanisms underlying parasite dissemination remain unknown. Genotypic differences among species ofL. braziliensishave been associated with different clinical forms of disease. The present work compared the function of monocytes obtained from patients with cutaneous leishmaniasis (CL) and DL in response to infection withL. braziliensisisolates of both these two clinical forms of disease. Mononuclear cells obtained from DL and CL patients were infected with differentL. braziliensisisolates, and numbers of infected cells, parasite load, respiratory burst, TLR2 and TLR4 expression and cytokine production were evaluated. DL isolates infected more monocytes, induced greater respiratory burst, and more cytokine production compared to isolates from CL patients regardless of the origin of monocytes (DL or CL). However, greater parasite multiplication and higher TLR2 and TLR4 expression were seen in monocytes from DL patients compared to CL following infection with DL isolates. Our results indicate the participation of both parasite genotype and host factors in the pathogenesis of DL.
Welcoming Wolves? Governing the Return of Large Carnivores in Traditional Pastoral Landscapes
Authors: Pettersson Hanna L. , Quinn Claire H. , Holmes George , Sait Steven M. , López-Bao José Vicente
Published: September 2021

Wolf populations are recovering across Europe and readily recolonize most areas where humans allow their presence. Reintegrating wolves in human-dominated landscapes is a major challenge, particularly in places where memories and experience of coexistence have been lost. Despite the observed expansion trends, little has been done to prepare communities for the return of these apex predators, or to understand what fosters and perpetuates coexistence. In this study, we present a theoretical framework for resilient coexistence based on four conditions: Effective institutions, large carnivore persistence, social legitimacy, and low levels of risk and vulnerability, nested within the social-ecological systems (SES) concept. To empirically show how the conditions can be manifested and interconnected, and how this knowledge could be used to improve local coexistence capacities, the framework is applied in a case study of human–wolf relations in Spain. We examined three traditionally pastoral landscapes at different states of cohabitation with wolves: uninterrupted presence, recent recolonization, and imminent return. We found that both the perceptions of wolves and the capacity to coexist with them diverged across these states, and that this was largely determined by a diversity of vulnerabilities that have not been recognized or addressed within current management regimes, such as economic precarity and weak legitimacy for governing institutions. Our results illustrate the importance of working in close contact with communities to understand local needs and enhance adaptive capacities in the face of rural transitions, beyond those directly related to wolves. The framework complements emerging tools for coexistence developed by researchers and practitioners, which offer guidance on the process of situational analysis, planning, and resource allocation needed to balance large carnivore conservation with local livelihoods.
Does the Heart Want What It Wants? A Case for Self-Adapting, Mechano-Sensitive Therapies After Infarction
Authors: Richardson William J. , Rogers Jesse D. , Spinale Francis G.
Published: September 2021

There is a critical need for interventions to control the development and remodeling of scar tissue after myocardial infarction. A significant hurdle to fibrosis-related therapy is presented by the complex spatial needs of the infarcted ventricle, namely that collagenous buildup is beneficial in the ischemic zone but detrimental in the border and remote zones. As a new, alternative approach, we present a case to develop self-adapting, mechano-sensitive drug targets in order to leverage local, microenvironmental mechanics to modulate a therapy's pharmacologic effect. Such approaches could provide self-tuning control to either promote fibrosis or reduce fibrosis only when and where it is beneficial to do so.
The Impact of Community Service Experience on the Undergraduate Students’ Learning Curve and Subsequent Changes of the Curriculum- A Quality Improvement Project at a Caribbean Medical University
Authors: Nauhria Samal , Nauhria Shreya , Derksen Irene , Basu Amitabha , Xantus Gabor
Published: September 2021

Background: Community service learning seems to positively impact undergraduate medical students’ practical procedural and communications skills. Events like health fairs also strengthen the bond between healthcare providers and the wider community. Recognizing this mutually beneficial situation, national accreditation agencies and medical boards have recommended incorporating community-based learning in the core undergraduate curriculum. Our university is the first to probe medical students’ perceptions of community service in our region to the best of our knowledge.

Objectives: We sought to analyze the experience of our students to improve the practical value of the curriculum.

Methods: This was a qualitative survey interviewing medical students volunteering at a health fair in a Caribbean Island aimed to screen gross cardio-vascular and metabolic abnormalities in the native adult population. The focus group interviews were processed, transcribed and coded for thematic analyses by independent observers.

Results: Overall, the students perceived CS as an opportunity to improve their clinical procedural and communications skills and to apply theoretical medical knowledge in practice to detect undiagnosed conditions like diabetes mellitus, hypertension and nutritional imbalance.

Pedagogical implications: We have increased practical laboratory sessions by 15% in the new semester to improve our students’ practical skills.

Conclusions: This is the first study that describes how community service may influence the individual learning curve of undergraduate medical students and may serve as a quality improvement tool to guide amendments to the curriculum. We opine that inter-agency, community-focused service promotes social, peer and active learning amongst undergraduate medical students.
The Role of GnIH in Biological Rhythms and Social Behaviors
Authors: Teo Chuin Hau , Phon Brandon , Parhar Ishwar
Published: September 2021

Gonadotropin-inhibitory hormone (GnIH) was first discovered in the Japanese quail, and peptides with a C-terminal LPXRFamide sequence, the signature protein structure defining GnIH orthologs, are well conserved across vertebrate species, including fish, reptiles, amphibians, avians, and mammals. In the mammalian brain, three RFamide-related proteins (RFRP-1, RFRP-2, RFRP-3 = GnIH) have been identified as orthologs to the avian GnIH. GnIH is found primarily in the hypothalamus of all vertebrate species, while its receptors are distributed throughout the brain including the hypothalamus and the pituitary. The primary role of GnIH as an inhibitor of gonadotropin-releasing hormone (GnRH) and pituitary gonadotropin release is well conserved in mammalian and non-mammalian species. Circadian rhythmicity of GnIH, regulated by light and seasons, can influence reproductive activity, mating behavior, aggressive behavior, and feeding behavior. There is a potential link between circadian rhythms of GnIH, anxiety-like behavior, sleep, stress, and infertility. Therefore, in this review, we highlight the functions of GnIH in biological rhythms, social behaviors, and reproductive and non-reproductive activities across a variety of mammalian and non-mammalian vertebrate species.
Eucalyptus Plantation Age and Species Govern Soil Fungal Community Structure and Function Under a Tropical Monsoon Climate in China
Authors: Liu Bing , Qu Zhaolei , Ma Yang , Xu Jie , Chen Pei , Sun Hui
Published: September 2021

Fungi perform crucial roles in nutrient cycles, but there is limited information on how soil fungal communities vary with stand age and tree species. Eucalyptus has been extensively planted in China, which has caused severe soil erosion and water deficiency due to short rotation management. In this study, the fungal community structure and potential function in Eucalyptus plantations with different ages (1–5+ years) and species (Eucalyptus urophylla × Eucalyptus grandis, Eucalyptus camaldulens, and Eucalyptus pellita) under a tropical monsoon climate in China were characterized by Illumina Miseq coupled with FUNGuild analysis. The results showed that the fungal alpha diversity decreased with an increase in the age of the plantation. Plantations of different ages and species formed distinct fungal communities and potential functional structures, respectively (p < 0.05), in which the age of the plantation contributed more to the variations. At high taxonomic levels, the soil fungal community changed from the dominance of orders belonging to Ascomycota (Pleosporales, Chaetothyriales, and Eurotiales) to orders belonging to Basidiomycota (Agaricales, Sebacinales, Cantharellales, and Russulales) with increasing plantation age. The community potential function shifted from the dominance of plant pathogens to a higher abundance of saprotrophs and symbiotrophs. The organic carbon of the soil was the key environmental driver to both the fungal community and potential functional structure. The results provide useful information on the importance of fungi for the management of Eucalyptus plantations.
Current Developments in Detection of Identity-by-Descent Methods and Applications
Authors: Sticca Evan L. , Belbin Gillian M. , Gignoux Christopher R.
Published: September 2021

Identity-by-descent (IBD), the detection of shared segments inherited from a common ancestor, is a fundamental concept in genomics with broad applications in the characterization and analysis of genomes. While historically the concept of IBD was extensively utilized through linkage analyses and in studies of founder populations, applications of IBD-based methods subsided during the genome-wide association study era. This was primarily due to the computational expense of IBD detection, which becomes increasingly relevant as the field moves toward the analysis of biobank-scale datasets that encompass individuals from highly diverse backgrounds. To address these computational barriers, the past several years have seen new methodological advances enabling IBD detection for datasets in the hundreds of thousands to millions of individuals, enabling novel analyses at an unprecedented scale. Here, we describe the latest innovations in IBD detection and describe opportunities for the application of IBD-based methods across a broad range of questions in the field of genomics.
Myeloid-Derived Suppressor Cells Alleviate Renal Fibrosis Progression via Regulation of CCL5-CCR5 Axis
Authors: Qiu Yue , Cao Yirui , Tu Guowei , Li Jiawei , Su Ying , Fang Fang , Zhang Xuepeng , Cang Jing , Rong Ruiming , Luo Zhe
Published: September 2021

Background

Renal fibrosis is inevitable in all progressive chronic kidney diseases (CKDs) and represents a serious public health problem. Immune factors contribute to the progression of renal fibrosis. Thus, it is very possible that immunosuppression cells, such as myeloid-derived suppressor cells (MDSCs), could bring benefits to renal fibrosis. Herein, this study investigated the antifibrotic and reno-protective effect of MDSCs and the possible mechanisms.

Methods

Murine and cell models of unilateral ureter obstruction (UUO) renal fibrosis were used. Bone marrow-induced MDSCs and granulocyte–macrophage colony-stimulating factor (GM-CSF) were pretreated before surgery. Kidney weight, pathological injury, extracellular matrix deposition, and epithelial–mesenchymal transition progression were examined. Transforming growth factor (TGF)-β1)/Smad/Snail signaling pathway involvement was investigated through Western blotting and quantitative PCR (qPCR). Accumulation of MDSC, CD4+ T cell, regulatory T (Treg), and T helper 1 (TH1) cell accumulation, and CCL5 and CCR5 expression level in MDSCs and non-MDSCs were evaluated using flow cytometry.

Results

In vitro- and in vivo-induced MDSCs significantly ameliorated UUO-induced tubulointerstitial fibrosis, inhibited the TGF-β1/Smad/Snail signaling pathway, and enhanced MDSC and Treg infiltration in the kidney while downregulating the TH1 cells. Both in vitro and in vivo experiments confirmed CCL5 elevation in the two MDSC-treated groups.

Conclusion

In vitro- and in vivo-induced MDSCs alleviated renal fibrosis similarly through promoting the CCL5–CCR5 axis interaction and TGF-β1/Smad/Snail signaling pathway inhibition. Our results indicate an alternative treatment for renal fibrosis.