bluuebunny/crossref_metadata_2025 huggingface dataset:
To determine morphology after administration of tetracycline and zinc chloride in adult albino rats and prenatal conceptus.
Authors: Muhammad Imran Rathore  , Allah Bachayo Rajar  , Pushpa Goswami
Published: January 2024

Introduction: Administration of tetracycline therapy is controversial during growing age as stated by earlier workers. However the effect of simultaneous administration of tetracycline & Zncl2 on pre-natal concepts has remained undocumented.Objective: To compare the effect on conceptus after maternal ingestion of tetracy-cline and Zncl2 by prospective experimental animal study model using adult albino rats.Methodology: Tetracycline & ZnCl2 was administrated to pregnant female albino rats two times therapeutic dose for 10 days. (from day 8 to day 18 of pregnancy.) Each animal was weighted on day 1, day 8 & day 18 of pregnancy. Abortion resulted on day 18th of pregnancy. Each group of pregnant animal were scarified on day 18 of gestation by overdose of either anesthesia, abdomen opened, uterus & both cornu containing conceptus identified, removed, there weight recorded, crown rump length was measured & was compared with similar value of control animals. The results were statistically analyzed to find out the significance.Result: Maternal administration of tetracycline decreased maternal bodyweight to 38.4 ±0.9gm. However simultaneous administration of ZnCl2 maintained body-weights to 41.4 ±0.7gm. The body weight and crown rump length (CR Length) in conceptus decreased by 4.52 ±0.10gm and 3.06 ±0.09 cm respectively. That tetracy-cline & ZnCl2 administration maintained the body weight & CR length by 5.46 ±0.09 gm and 3.79 ±0.13gm respectively.Conclusion: Pre-natal administration of Tetracycline alone cause reduction in ma-ternal body weight as well as reduction in body weight & CR length of rat conceptus. However simultaneous Zncl2 maintain body weight & CR length leading to growth of the rat conceptus.Keywords: Tetracycline, ZnCl2, Rat Conceptus. Crown Rump Length (CR Length).
Seroprevalence of Hepatitis-B virus and Hepatitis-C virus in pregnant women in Hyderabad.
Authors: Afsheen Qazi  , Bhawani Shanker  , Rajesh Rathi  , Narindar Kumar
Published: January 2024

Introduction: Infections of the hepatitis B virus (HBV) and the hepatitis C virus (HCV) are major global public health problem. Approximately 350 million and 190 million people worldwide are infected with HBV and HCV respectively. 

Objective: To evaluate seroprevalence of hepatitis B and C among pregnant  women of Hyderabad.

Methodology: This prospective cross sectional study conducted at Pathology department of a tertiary care hospital of Hyderabad during Jan 2019 to July 2019. During period of study data of 500 pregnant women recorded on pre structured proforma after taking informed consent. Causes of hepatitis other than B or C virus were excluded. Status of HCV and HBV was confirmed using Elisa method.

Results: showed 7% seropositivity for HCV and 4.2% for HBV among pregnant women.

Conclusion: Among pregnant females, in Hyderabad  there is a higher seropositivity of anti HCV antibodies as compared to HBsAg. Both seropositivity to HBV and HCV was found to be more prevalent in the 30-39 year age group.

Keywords: Pregnant women, Hyderabad, Seroprevalence HCV, Seroprevalence HBV.
Heterotopic pregnancy: A case Report.
Authors: Qamar-un-Nisa  , Hemlata Maheshwari  , Asma Jabeen
Published: January 2024

Heterotopic pregnancy (HP) is a rare phenomenon. It is defined as simultaneous presence of intrauterine and extrauterine pregnancy. A case of HP is discussed. A young patient presented initially with two months amenorrhea and lower abdominal pain. Initial ultrasound showed only 6 weeks intrauterine pregnancy. But, due to increasing severity of pain ultrasound was repeated showing heterotopic pregnancy, which was later confirmed by histopathology.

Keywords: Tubal pregnancy, Ectopic pregnancy, Heterotopic pregnancy .
Frequency, Management and Outcome of Postpartum Hemorrhage at a tertiary care Hospital.
Authors: Nailla Yousuf  , Prof. Farida Farooq  , Khalid Yousuf  , Raisham Ali  , , Farkhana Yasmeen  , Shabana Ramzan
Published: January 2024

Introduction: According to WHO, world estimates of 2017, 295 000 maternal deaths were reported all over the world and maternal mortality rate ranged from UI 99 to 243 per 100 000 live births. There has been 35% reduction since year 2000. Similarly, there has been 51% reduction in maternal mortality rate in Pakistan. 94% of all maternal deaths occur in low and lower middle-income countries. The major complications that account for nearly 75% of all maternal deaths are: severe bleeding mostly Post-Partum Hemorrhage (PPH), Postpartum sepsis, pre-eclampsia and eclampsia and other.

Objective: To find out the frequency of patients presenting with PPH among all patients delivered during the study period, their management and subsequent morbidity and mortality.

Methodology: This retrospective study was conducted between January 2018 to December 2019 at the department of Obstetrics and Gynecology PUMHS Hospital Nawabshah, Benazirabad.  The demography, parity, gestational age, mode of delivery and type of PPH developed as well as treatment for PPH and subsequent morbidity and mortality were all documented. Data analyzed using SPSS version 20.

Results: During study period frequency of PPH was 32.73 per 1000 deliveries, prevalence of primary PPH was 90.51%. Among the causes of PPH, Uterine atony was the leading cause 42/137 (30.65%). 56 (40.87%) patients were managed in the ICU for ventilatory &, inotropic support and septic shock, management. Mortality was 7(5%).

Conclusion:  Majority of patients are of primary PPH and uterine atony remains the most common cause of PPH which requires prompt and timely management as per guidelines.
Bilateral multiple giant juvenile fibroadenomas of breast.
Authors: Ghulam Rasool Memon  , Mairaj Muhammad  , Major Amir Iqbal Ali
Published: January 2024

A case of adolescent girl, with bilateral giant fibroadenomas. On history first appeared as small nodules at the age of eleven years and attempt mass of 1855 grams by seven nodules of various sizes measuring, largest 15 x 14 x 10 cm and smallest 1.5 x 1.5 x 1 in dimensions. Although these developed insidiously over the period of seven years, patient ignored the lesion as well the increased in size. Soon after marriage, her husband realizes that the lesions needs consultation and brought her to Combined Military Hospital Chhor Umerkot.
Ruptured ectopic pregnancy in the rudimentary horn of a Unicornuate uterus. A case report.
Authors: Qamar ur nisa  , Erum Samreen Siddiqui
Published: January 2024

Ectopic pregnancy in rudimentary horn of a Unicornuate uterus is a very rare phenomenon, and usually presents in second trimester with rupture and hemoperitoneum. Diagnosis before its rupture is very challenging.

We are presenting a case report of ruptured ectopic pregnancy in rudimentary horn of a Unicornuate uterus. A 26 years old gravida 4 para 2 with one early miscarriage, having first vaginal delivery and second delivery by Caesarean section due to fetal distress, presented in emergency with 4 months amenorrhea, severe lower abdominal pain for 2 days and signs and symptoms of shock. There was severe anemia and abdominal tenderness. Ultrasound showed, left ruptured ectopic pregnancy with 16 weeks size dead fetus present in the pelvic cavity and massive hemoperitoneum. After resuscitation laparotomy was performed. There was ruptured left rudimentary horn pregnancy. The horn was reserved and uterus was repaired. Multiple blood transfusions were done. Post-operative period remained uneventful.
Gastrointestinal and Hepatic manifestations of COVID-19 in patients attending tertiary care hospital
Authors: Darshan Kumar  , Anoshia  , Zunaira Nawaz  , Muhammad Kunain  , Ali Afsar  , Fatima tuz Zehra
Published: January 2024

Introduction: To evaluate the frequency of Gastrointestinal (GI) symptoms and elucidate the association of GI symptoms and hepatic injury markers with the severity of COVID-19 and mortality.Methodology: Single-centered observational study recruited 160 confirmed COVID-19 positive patients who were admitted in Medical Unit-1/C1 of Civil hospital Karachi, Pakistan from 21 February to 30 April 2021. Data was ana-lyzed using SPSS version 23.0.Objective: To evaluate the frequency of GI symptoms and elucidate the as-sociation of GI and hepatic abnormalities with the severity of COVID-19 and its mortality.Results: Among 160 patients, 20% presented with digestive symptoms; ab-dominal pain (33.1%), and nausea (33.1%) being the most common. GI symptoms and liver injury markers notably ALT, AST, and GGT were signifi-cantly associated with severity of disease (p value<0.05), ICU admissions (p value<0.01), and poor outcomes (p value<0.01).Conclusion: COVID-19 infected patients presenting with GI symptoms and liver dysfunction have a worse prognosis and needs to be addressed on ur-gent basis to avoid complications and reduce mortality.Key words: Covid-19, Hepatic injury, Gastrointestinal symptoms, Liver dysfunction.
Histomorphometric effects of Raphanus Sativus leaf ex-tract on Carbon Tetrachloride induced hepatotoxicity.
Authors: Shazia Parveen  , Sajjad Ali Almani  , Sana Kashif  , Muhammad Shahab Hanif  , Ayesha Asad  , Mozna Talpur
Published: January 2024

Introduction: Carbon tetrachloride (CCl4) adversely affect the structural/ and or functional properties of the hepatic tissue, leading to grave implica-tions. Currently plant-based compounds have gained sufficient space in the treatment of liver diseases. Among such plants is Raphanus sativus, a cru-ciferous plant also commonly called Radish, which has since long been used in traditional medicine.Objective: To evaluate the protective role of Raphanus sativus in CCl4-induced hepatotoxicity through assessment of liver function and oxidative stress markers in albino Wistar rats.Methodology: This Quasi-experimental study was conducted between Sep-tember 2019 to March 2020 at the Postgraduate Research Laboratory Isra University, Hyderabad. Albino Wistar selected by non-random purposive sampling were divided equally into three different groups: Group A (control group), Group B (CCl4 experimental group), and Group C (CCl4 plus Raphanus sativus group). Blood samples were collected through cardiac puncture followed by hepatic histopathological analysis using light micro-scope. Data was analyzed using SPSS version 24, with ANOVA and Post hoc Tukey’s analysis used for comparison of different study variables.Results: Statistically significant rise relative liver weight of group B rats compared with the group A and C rats (P <0.05). Moreover, statistically sig-nificant (P <0.05) rise in serum markers of hepatic functions was observed after CCl4 administration in Group B. Treatment with Raphanus Sativus ad-ministration significantly reduced serum levels of LFTs (p<0.05). There was a significant decline in the plasma levels of oxidative markers in group B while marked histopathological changes like necrosis, sinusoidal dilatation and congestion observed among animals of group B.Conclusion: Raphanus Sativus exerts an anti-oxidative, and hepato-protective effect against CCl4-induced hepatic tissue damage.Keywords: CCl4, Hepato-protective, Raphanus Sativus.
SARS COVID-19 and neurological indicators and its consequences in healthcare provider.
Authors: Bushra Tahreem  , Toba Samreen  , Sana Mehreen
Published: January 2024

In China, as well as other Asian and European countries, the new coronavirus sick-ness (COVID-19) has disseminated quickly. Patients, health experts, and the over-all community are under tremendous mental stress, which can precede to headaches, sleep disorders, depression, and anosmia, among other issues. During the COVID-19 epidemic, experts have established an agreement on the admission of individuals with serious mental disease to mental health facilities. Nonetheless, the COVID-19 has ascended as a severe warning to mental condition around the world due to its rapid spread. The impact of mental health on health practitioners is examined in this article. Review the many neurological signs of the COVID-19 disease as well.

Keywords: COVID-19, Mental health, Cerebrovascular accident, health care provider
Outcome of trial of labor and causes of its failure in patients with previous one lower segment caesarean section
Authors: Rozina Mujeeb Sahito  , Raishem Ali  , Shabana Ramzan  , Rashida Akber  , Mujeeb ur Rehman sahito  , Shehzad Memon
Published: January 2024

Introduction: As per guideline of American College of Obstetricians and Gynecologists, repeat cesarean section should be avoided unless there is absolute contraindication. However, in patients having previous c-section, the trial of oxytocin/prostaglandin for induction of labor has controversial report.Objectives: To determine the outcome of the trial of labor and causes of its failurein patients with a previous one lower segment cesarean section.Methodology: This descriptive cross-sectional study was conducted at Departmentof Obstetrics & Gynecology at Peoples Medical College Hospital, Nawabshah for theperiod of six months from January 2021 to June 2021. During this period 100 patients, aged 20-45 years, with term gestation and history of previous lower segmentcesarean section, having vertex presentation singleton pregnancy were included.Results: The mean age of 100 enrolled patients was 34.69 ±1.44 years. Trial of laborfound successful in 64 women; in 45 (70.3%) there was spontaneous vaginal delivery, 14(21.8%) had forceps delivery and 5 (7.8%) had vacuum delivery. Among 36patients where trial of labor remained unsuccessful, cesarean section was performed. The trial of labor was failed secondary to failed progress of labor (n= 17,47.2%), fetal distress (n=11, 30.5%), scar dehiscence (n=3, 8.3%) and antepartumhemorrhage (n=5,13.8%). There was no mortality of fetus or mother in our study.Conclusion: Trial of labor should always be attempted in women with previous cesarean sections with continuous monitoring, provided there is no absolute contraindication, as it may be successful in most cases.

Keywords: Cesarean Section, Trial of Labor, Failure, lower segment
Role of Beta Blockers and Band Ligation in upper gastrointestinal tract bleeding.
Authors: Luqman Anwar  , Urooj Fatima  , Madiha Mehmood
Published: January 2024

Objective: To sort out the combine role of beta blockers and band ligation in upper gastrointestinal bleeding

Methodology: In this prospective observational study 563 patients were included, (mean age 47 ±6 years, males 69%) with liver cirrhosis and deterioration from Medical ward Mayo hospital Lahore. All the patients had cirrhosis and esophageal varices confirmed by endoscopy. In hospital cirrhotic patients with hypertension and liver cell deteriorations. All the record of betablocker use and band ligation was carefully recorded. Data regarding patient presentation and characteristics were keenly monitored and observe with treatment and improvement as major variables. Mortality was taken as major influential factor. Linear regression model was used.

Results: Overall, there were 426 patients getting pharmacological treatment and have band ligation treatment simultaneously. One Hundred and thirty-seven had gastrointestinal bleeding during study time. Standard deviation of patients who had no recurrence of bleeding from last two years was 67±4. Low level of serum albumin, presence of ascites, and treatment with betablockers were the only independent variables that directly influenced the bleeding. The percentage of patients who had only once bleeding during study period was 23±2 percent. The major effects by be ta blockers were preserving after band ligation of source of bleeding.

Conclusion: This study demonstrates that best treatment of bleeding in upper gastrointestinal tract is beta blockers, with the use of b and ligation where it is needed. Strict monitoring and guidelines should be under consideration before stop the beta blockers upper gastrointestinal bleeding patients.

 Keywords: Beta blockers, Band Ligation, Upper Gastrointestinal Tract
Variations in Serum Ferritin in Different Professionals of Mirpurkhas.
Authors: Chohan Habib-ur-Rehman , Syed Hafeez ul Hassan , Habib Chohan Rehana
Published: January 2024

Introduction: Serum ferritin has been shown to be a good biomarker of body iron stores. Iron is essential mineral that functions to bind oxygen as a part of Heme in Hemoglobin and Myoglobin1. Ferritin, a major protein regulating iron homeostasis, is used as a biomarker for iron status and low grade inﬂammation, which results in free radical damage to cells and tissues18-19. Accordingly, recent studies demonstrated that serum ferritin concentrations are correlated with diabetes mellitus, insulin resistance, metabolic syndrome, ischemic heart disease, cardiovascular disease, and nonalcoholic fatty liver disease (NAFLD) in healthy men and obese patients.

Objective: The study was aimed to evaluate possible variations in serum ferritin levels in different professional of Mirpurkhas.

Methodology: 250 subjects were randomly selected from the local community of Mirpurkhas from OPDs of Civil Hospital Mirpurkhas and Muhammad Medical College Mirpurkhas. Their Serum ferritin was determined by ELISA. And the data was analyzed by SPSS 15.

Results: This was a cross-sectional study. Out of 250 subjects 170 (68%) were male and 80 (32%) were female. The mean age was 55.20 ± 11.046 year the mean height of subjects was 1.6732 ±.09637 meters while the mean weight was estimated as 65.50 ±11.589 kgs. The mean BMI was calculated as 24.2772 ±3.34493 kgs/m2. Serum ferritin was ranged between 46-450 ng/ml of blood with mean serum ferritin 226.32 ± 99.027 ng/ml of blood. Serum Ferritin in male was found 233.59 ±98.366 ng/ml of blood and in female was found to be 210.88 ± 99.268 ng/ml of blood. It was found that the mean serum ferritin in teachers was 181.00 ± 42.312 ng/ml, in doctors 286.67 ±67.788 ng/ml, in farmers 267.91 ±78.188 ng/ml, in laborers 174.40 ±108.939 ng/ml, in house wives 201.14 ±112.797 ng/ml, in Clerks office superintendents 205.50 ±16.338 ng/ml, in peon/ masi/ attendants 233.00 ± 135.262 ng/ml, in unemployed 120.00 ± .000 ng/ml, in retired 304.20 ± 89.084 ng/ml and in Businessmen 193.17 ±89.084 ng/ml. A comparison was made between serum ferritin values of different professionals by applying ANOVA test and found that there is a significant difference between serum ferritin values of different professional with highly significant p=.000 value.

Conclusion: It was found that serum ferritin level was not similar in all profession and different type of work do affect its level inside the body.
Pseudo-neoplastic Lesions of Prostate and the Diagnostic Deception
Authors: Memon Ghulam Rasool , Gul Maria  , Momina Muhammad
Published: January 2024

Introduction: Many pseudo-neoplastic lesions of the prostate gland are recognized. Histologically these lesions mimic the adenocarcinoma of prostate. Pseudo-neoplastic lesions comprise of different glandular and non-glandular or solid patterns. Largely emphasized on the epithelial origin but some stromal and solid lesions are also important. In developing countries, the routine Hematoxylin and eosin (H&E) stain is most commonly used to stain the histological tissue sections. The other stains and molecular studies are not frequently used. The pseudoneoplastic lesions are so obscure and deceptive that sometimes it become very difficult to recognize. The diagnostic facilities both in government and private sector should have at least the facility of immunohistochemical staging to avoid misinterpretations.

Methodology: This retrospective study performed at Muhammad Medical College Mirpurkhas Sindh. 192 specimens of radical prostatectomy (RP) and transurethral resection of the prostate (TURP) received between January 2015 to December 2017 were retrieved for review. All retrieved blocks processed as per standard histopathological techniques. Fresh tissue sections taken and stained with H&E.

Results: All tissue sections reviewed to observe the glandular patterns, their architectural morphology, cytological changes and inflammatory process. The lesions were distinguished on epithelial origin and glandular patterns. Cases of benign prostatic hyperplasia were 169 (88 %), adenosis 06 (3.12 %), reactive hyperplasia 06 (3.12 %), Post atrophic hyperplasia 05 (2.6 %), benign stromal proliferation 02 (1 %) and prostate carcinoma 04 (2%).

Conclusion: Many pseudoneoplastic lesions of the prostate are the mimicker of adenocarcinoma. On H&E stains it sometimes become difficult to differentiate the lesions. The histomorphological diagnosis of these lesions should be facilitated at least by immunohistochemical stains at diagnostic tcenters.t

 

Keywords: Immunohistochemistry, Transurethral resection of prostate (TURP), Radical prostatectomy (RP). Hematoxylin and Eosin (H&E).
An Audit of 138 Patients Admitted with Lump in the Neck in Surgical Department of Services Hospital Lahore, (SIMS)
Authors: Nazar Netasha , Syed Abdul Razzaq , Muhammad Ahmed  , Khalil Sidra
Published: January 2024

Introduction: Neck swellings are very common problem in head and neck region. Causes are highly variable, ranging from simple treatable disease to a metastatic incurable carcinoma. The common causes may differ depending upon the different geographical location, gender and age of the patients. Therefore, the knowledge of local causative factors is important to avoid diagnostic delay. Commonly presenting head and neck masses are due to lymph node, thyroid and salivary gland enlargement. In third world countries, infective causes are most common. Malignant neoplasms were the second most common group. Therefore, frequent audit is necessary for prompt diagnosis and further work up.

Objective: An audit of 138 patients admitted with neck swelling in surgical department of a tertiary care Hospital of Lahore.

Methodology: This cross-sectional study was carried out at Department of Surgery, (unit-1) Services Institute of Medical Sciences Lahore, (SIMS) during January 2014 to July 2015. All patients who presented with neck swelling during study period were included. Diagnosis made after taking clinical history, examination and relevant laboratory work up.

Results: Out of 138 patients with lump in the neck, 93 (67.39%) were female and 45 (32.60%) were male. The commonest swelling is tuberculous lymphadenitis that is 34 (24.63%) and 9 (6.52%) were lymphoma and 4 (3%) with reactive hyperplasia. 49 (35.5%) arose from thyroid (40 benign and 9 malignant). Among the benign swellings, 15 were solitary nodular goiter, 12 were Multinodular goiter and 13 were diffuse thyroid goiter, 11 were Thyroglossal cyst. Other causes included sebaceous cyst 12 (8.69%), lipoma 19 (13.67%), thyroglossal cyst 11 (8%) and carcinoma of thyroid 9 (6.52%)

Conclusion: The most common cause of neck lump is thyroid disease and tuberculous lymphadenitis. Early diagnosis of tuberculosis and goiter is crucial for appropriate management.

 

Keywords: Head and Neck Swellings, Lymph Nodes, Tuberculous lymphadenitis, Goiter
Prevalence of Pre-Diabetic State among Medical Students of Muhammad Medical College
Authors: Mubeen Nasir  , Umair Mustafa  , Sana
Published: January 2024

Introduction: Diabetes is one of the most prevalent disease in Pakistan. Pre-Diabetes is the predisposition to diabetes. This study was conducted to identify the high-risk pre-diabetes individuals and the associated risk factors.

Methodology: A cross section al, descriptive study was conducted among medical students of Muhammad Medical College, Mirpurkhas. Total 100 were identified by using convenience sampling technique, after taking informed consent. WHO recommended procedure Oral Glucose tolerance test were performed and a face to face interview was conducted to collect information to identify associated risk factor by using closed ended pre- tested questionnaire. Data was entered and analyzed by using SPSS version 16.

Result: In total study sample of 100 patients; common age group was 20-22 years (n=49, 49%) and majority were male (n=56, 56%). Family history was present in 64% of study sample. Although all participants were disease free, results of oral glucose tolerance test showed that12% were at pre-diabetic state (FBS>110 &RBS>140). Among these 12 participants, 5(41.7%) were overweight, 4(33.3%) were obese, while 3(25%) were having normal BMI. Among this cohort of prediabetic, 75% have positive family history of diabetes, 50% spend 2-5 hour free with no physical activities, 90.9% take junk food, 91.7% take stress about their family/study and 50% have family history of obesity.

Conclusion: Results of current study showed 12% prevalence of pre-diabetic among medical students. The family history of diabetes, obesity, sedentary lifestyle, stress and use of junk foods are associated risk factors. As a preventive measure, health education should be given to all medical students particularly high-risk group.

 

Key Words: Pre-diabetic state, Oral glucose tolerance test, Overt Diabetes.
Assessment of significant variables to improve admission and teaching learning processes in a medical school.
Authors: Syed Imran Mehmood  , Borleffs Jan C.C.
Published: January 2024

Introduction: Current selection methods in medical schools emphasize academic competence only, somewhat to the detriment of other essential competencies. Academic grades are frequently considered as the predictors of good academic performance in medical schools and therefore many medical schools still select applicants predominantly on this basis.

Objective: To assess this long-standing trend in order to point out the lacunae associated with it and to explore this effect with a view to improve teaching and learning process.

Methodology: During this retrospective longitudinal study, we studied the students (n=539) admitted to the college of medicine, King Khalid University, Saudi Arabia, between 2006 and 2011. During these years study conditions (i.e. admission procedure, study program and assessment) remained unchanged. The scores of higher school certificate (HSC) were correlated with study duration (number of semesters) and grade point average (GPA). Pearson’s correlation and regression analysis were carried out using effect model.

Results: The results of this study do not demonstrate a correlation between HSC scores and study duration (r = -.018). The relationship bet ween HSC scores and cumulative GPA was moderate positive (r = .476). The HSC scores were found to be poor predictors of the subsequent academic performance (R2 = .273).

Conclusions: The HSC score is a poor predictor of the subsequent academic performance. Our intuition, and perhaps our experience, suggests that study time should be positively associated with grades. However, it is not always the case as study duration-grade association may not be true.

 

Keywords: School admission criteria, Medical education, Students, Undergraduate.
Caesarean Scar Endometriosis: What protocols should surgeons follow?
Authors: Madhu Bala Sharma  , Shaista Farooque  , Yasmeen Nawaz  , Ammar Saleem
Published: January 2024

Endometriosis is defined as presence of functional endometrial glands and stroma outside uterine cavity. Caesarean Scar Endometriosis (CSE) is a rare condition and is difficult to diagnose. We are reporting a case of CSE involving skin and subcutaneous tissues. The incidence pathogenesis, diagnosis, treatment and preventive measures are discussed.

Key Words: Endometriosis, Scar, Caesarean Section.
The Significance of the Development of the Salted Fish Industry for Community Economic Growth from an Islamic Economic Perspective (Study on Baai Island, Kampung Melayu, Bengkulu City)
Authors: Novia Sari Yuyun , Yustati Herlina , B Idwal
Published: January 2024

This research was conducted on Baai Island, Malay Village, Bengkulu City. The purpose of this study was to determine the Significance of the Development of the Salted Fish Industry for the Growth of the Community Economy in the Perspective of Islamic Economics. This research is qualitative. Data collection methods through interviews with sellers, workers, and buyers of salted fish in the baai island area. Based on the formulation of the problem in this study, namely: How is the development of the Baai Island salted fish processing industry and how is the impact of the development of the Baai Island salted fish industry on the economy of the community in the perspective of Islamic Economics? The research findings show that the business development carried out is through 2 methods online and in person. The impact of the development of this industry itself is the increased income of the community, the welfare of the Baai Island community, and the fulfilled needs of life.
Potential Novel Treatments for Parkinson’s Disease
Authors: Kanyadan Pooja
Published: January 2024

This review aims to evaluate novel developments in treatments for Parkinson’s disease that focus on slowing, stopping, and/or reversing the neurodegeneration associated with the disease. Parkinson’s disease (PD) is a neurodegenerative disease that affects dopaminergic neurons in the substantia nigra, located in the basal ganglia of the brain. This region also contains high levels of alpha synuclein, a protein found abundantly in the brain due to its important role in neurotransmitter release. α-synuclein has been found to be misfolded and overexpressed in people with PD, which leads to fibril formation and aggregation, which directly interfere with basic cellular processes and results in neurodegeneration. In PD patients, dopaminergic neurons are most affected; therefore, an artificial supply of dopamine must be provided to them via dopamine precursors that can cross the blood-brain barrier. However, these medications fail to slow, stop, or reverse the progression of PD and merely pose as treatments for physical symptoms, such as tremors. Researchers are now focusing on 2 major avenues for new PD treatments: treatments that target α-synuclein aggregates/Lewy body assemblies and treatments that focus on replacement of lost dopaminergic neurons in the brain. The use of antibodies (immunotherapy) to target and clear αsynuclein aggregates or the upregulation of genes that encode autophagic mechanisms to destroy dysfunctional proteins were shown to reduce α-synuclein aggregation and behavioral deficits in mice. Results from clinical trials have shown a 96.5% reduction in the concentration of extracellular α-synuclein aggregates, and doses were well tolerated with no serious side effects. In order to rebuild the neurons that were lost to PD neurodegeneration, a renewable source of dopamine-producing cells that can integrate into the host brain and survive for years is required. More specifically, the reprogramming of astrocytes can be used to develop functional dopaminergic neurons. To reprogram the astrocytes and fibroblasts, the RNA binding protein PTB was suppressed; PTB suppresses numerous neuronal genes required for neuronal maturation, thus, downregulation of PTB generates functional, mature neurons. When in vivo astrocyte reprogramming was performed in a mouse model of PD, researchers found new, successful dopaminergic neurons in the substantia nigra and increased dopamine levels. Although both avenues for treatment require further clinical trials and testing in human subjects, they both hold significant promise in the future.
Recursos violinísticos de la tradición musical de danza de tijeras en Huanta, Ayacucho
Authors: Valiente Estrada Karen Giselle
Published: January 2024

La danza de tijeras presenta una música particular en comparación con otras expresiones musicales de la tradición andina. Su interpretación del violín ha adquirido características propias que se vinculan con una gama de recursos técnico-expresivos, transmitidos a través de la imitación en la tradición aural, y sobre los cuales no hay estudios suficientes. En este trabajo, se aborda el contexto de la práctica tradicional del violín en Huanta, Ayacucho, reconociendo las dinámicas de aprendizaje del instrumento y el rol de liderazgo musical que asume el violinista. Como estudio central, se analizan los recursos melódicos y de ornamentación empleados durante la ejecución del violín, e indicados mediante transcripciones musicales realizadas a partir de una fuente sonora. Paralelamente al reconocimiento de estos recursos, se devela la relación existente entre su concreción sonora en la música y la expresión coreográfica del danzante o dansaq. Los resultados de la investigación permiten observar que la ejecución de los recursos técnico-expresivos en el violín constituye un componente estético sustancial en la tradición musical de la danza de las tijeras.
La enseñanza de la música en su relación con la coordinación óculo manual: una revisión teórica
Authors: Cabello Santillán Yisa Nadia
Published: January 2024

La presente investigación está centrada en la revisión bibliográfica sobre la coordinación óculo manual (COM) en textos orientados a la enseñanza de la música, un tema vinculado a las ciencias de la salud que ha ido ganando espacio durante las dos últimas décadas por su aplicación como recurso pedagógico y metodológico. La investigación se desarrolla en dos partes: en la primera, se hace un reconocimiento del enfoque interdisciplinario en que se encuentra la enseñanza de la música en el siglo xxi y, como marco conceptual, se abordan generalidades sobre el desarrollo psicomotor y la coordinación óculo manual en su relación con la música. En la segunda parte, se presenta un análisis conceptual y disciplinario de estos textos, proponiendo una clasificación de sus acercamientos teóricos. Se distinguen aquí los siguientes: propuestas de enseñanza-aprendizaje enfocadas en el proceso de la lectura musical; materiales generados específicamente para la didáctica del lenguaje musical; y propuestas de ejercicios aplicados a la enseñanza instrumental. En las conclusiones se aprecia cómo estos acercamientos teóricos por parte del educador musical han sido motivados fundamentalmente por el interés en optimizar su calidad de enseñanza.
La ausencia de un lenguaje común: un panorama estético-musical de la composición para cuarteto de guitarras en el Perú
Authors: Baltazar Laguna Marco Agustín
Published: January 2024

El presente trabajo aborda las características estético-musicales del repertorio para cuarteto de guitarras compuesto en el Perú en los últimos veintisiete años, analizado desde los aspectos formal, melódico, armónico y tímbrico. La necesidad del análisis se debe a la heterogeneidad de un corpus significativo de obras y a la búsqueda de criterios interpretativos. En la contextualización, se explora la historia de los cuartetos formados en el país y se devela su relación con las tendencias musicales generales que se han presentado en la composición académica, distinguiendo las diferencias entre una tendencia modernista, que corresponde al siglo xx, y las múltiples tendencias que han ido surgiendo en el siglo xxi. La observación de estos procesos permite determinar la existencia de una pluralidad estética en la composición para cuarteto de guitarras en este espacio y tiempo.
LEAN MANAGEMENT AS AN INNOVATION TO REDUCE COMPLAINT HANDLING TIME IN HOSPITAL
Authors: Munaa Nihayatul , Faiz Faizatul Ummah , Vica Nahardian Vica Rahmawati , Rateh Nali Rateh
Published: January 2024

Customer service is a service product from Hospital X. The better the service at a hospital, the number of complaints will decrease. In the customer service flow for Hospital X there is Complaint Handling and monitoring and evaluation. The purpose of this research is to provide lean management innovation as an effort to reduce the waiting time for complaint handling. In this study the method used was community service with the time period April-July 2023 at Hospital X. The column for patient complaints at the hospital was not clear and detailed. So the added innovation is to cut steps or steps that lack value by creating or adding a complaint menu on the Hospital website. The complaints menu contains information and complaints services
INCREASING PUBLIC KNOWLEDGE THROUGH HEALTH EDUCATION ON RADIO THROUGH TALKSHOWS WITH TITLE “THE ROLE OF VOLUNTEERS IN HELPING COMMUNITIES AFFECTED IN DISASTER” IN PROGRAM 1 RRI MALANG
Authors: Sunaryo Eri Yanuar Akhmad Budi , Evi Nurul , Rahmatika Qory Tiffani
Published: January 2024

Volunteers are individuals who voluntarily donate their time and effort to make a positive contribution to others without expecting financial or material rewards. The roles of volunteers before a disaster (pre-disaster) is as supporters in policy formulation, planning, disaster risk reduction, and community disaster prevention and preparedness. This community service (PKM) aims to provide education about the role of volunteers, especially health volunteers, in helping people affected by disasters. The PKM activity was aimed at listeners of the Kiprah Indonesia program, which was broadcasted on Program 1 of the LPP RRI Malang Culture Channel. This PKM activity took the form of a talk show held live at the Kiprah Indonesia event on the Culture Channel Program 1 RRI Malang 105.3 FM, and was also broadcast via live streaming on the official RRI Malang Youtube channel. The community service (PKM) was carried out on December 29, 2022, by broadcasting live on the Kiprah Indonesia event on Program 1 Culture Channel LPP RRI Malang 105.3 FM. The PKM program was a radio talk show. Health education provided by this radio talk show was expected to increase public knowledge about the disaster management cycle, the definition/understanding of volunteers in disaster management, the working principles of volunteers, the five pillars of volunteers in disaster management, the task/duties of volunteer organizations, volunteer management, and also landslide and flood disaster mitigation. This talskhow also aims to provide mitigation and preparedness measures to deal with disasters, especially floods and landslides
IMPROVING THE QUALITY OF LIFE OF THE ELDERLY THROUGH SCREENING FREQUENCY OF PHYSICAL ACTIVITIES IN MALANG
Authors: Sunaryo Eri Yanuar Akhmad Budi , Zariroh Zirroh Alin
Published: January 2024

Introduction: The welfare of the elderly can be reflected through their health conditions, both physically, spiritually and socially, which allows everyone to live a productive life socially and economically. Modern lifestyles have changed human attitudes and behaviors, including diet, smoking, alcohol consumption and drugs as a lifestyle so that patients with degenerative diseases (diseases due to decreased organ function) are increasing and threatening lives. Purpose: The purpose of this community service is to screen the Frequency of Physical Activity in the elderly. Methods: The methods used are measurement and examination as well as providing education. The method of measuring the Frequency of Physical Activity and counseling about a healthy lifestyle for the elderly in Malang. Results: The results of the screening conducted, of the 55 participants who took part in the examination, found 19 people were often active, 11 people experienced problems related to physical activity with infrequent activity, and 15 people experienced problems very rarely active. Conclusions: This community service runs smoothly and can provide benefits to the community. The results of this community service can be used as a reference for improving the health status of the elderly.
IMPROVING THE QUALITY OF LIFE OF THE ELDERLY THROUGH WEIGHT SCREENING IN MALANG
Authors: Evi Nurul , Setyowati Nurul
Published: January 2024

Introduction: The welfare of the elderly can be reflected through their health conditions, both physically, spiritually, and socially, which allows everyone to live a productive life socially and economically. Modern lifestyles have changed human attitudes and behaviors, including diet, smoking, alcohol consumption and drugs as a lifestyle so that patients with degenerative diseases (diseases due to decreased organ function) are increasing and threatening lives. Purpose: The purpose of this community service is weight screening in the elderly. Methods: The methods used are measurement and examination as well as providing education. The methods used are measurement and examination as well as providing education. The method of measuring body weight and conducting counseling on healthy lifestyles for the elderly in Malang. Results: The results of the screening carried out, of the 55 participants who took part in the examination, found 29 people Normal, 11 people experienced problems related to Weight with Obesity, and 15 people experienced problems less than normal. Conclusions: This community service runs smoothly and can provide benefits to the community. The results of this community service can be used as a reference for improving the health status of the elderly
MEDICAL TEAM SUPPORT FOR TABLE TENNIS EVENT – LPTK CUP XXI UM 2023
Authors: Ramadhan Muhammad Putra , Sishartami Lintang Widya , Aditya Ronal Surya , Rahmatika Qory Tifani , Sunaryo Eri Yanuar Akhmad Budi , Evi Nurul , Masfi Achmad , Afiani Nurma , Widjayanti Yhenti
Published: January 2024

Introduction: LPTK CUP strives to improve relationships and unity among LPTK (Lembaga Pendidikan Tenga Kependidikan) members. It achieves this by merging competitive elements with entertainment to promote a feeling of camaraderie and cooperation. Furthermore, LPTK CUP includes a range of sports competitions, including table tennis. Purpose: This study aims to comprehend the medical team's involvement in providing support during the table tennis event at LPTK CUP XII UM 2023. Method: The medical team is crucial in delivering general and specialized healthcare services (for sports injuries) throughout the table tennis competition at LPTK CUP XXI UM 2023. Additionally, various approaches are employed in this event, including 1) Acquiring Medical Equipment, 2) Collaborating with Relevant Entities, 3) Arranging the Placement of the Medical Team, 4) Conducting Screening and Medical Services, and 4occurredviding Health Education. Result: Most table tennis participants are less than 50 years old. Several injuries occur during the match, namely Abrasion, Shoulder Sprain, and Ankle Sprain. The injury management provided is based on the Rice Method for sports injuries.
UTILIZATION OF SOCIAL MEDIA AS A QUARTER LIFE CRISIS EDUCATION MEDIA
Authors: Rahmayanti Sheilla , Pramudya Dandy Arie , Hayuningrat Fathimah Az-Zahra , Esrarf Lubna Salsabila , Naia Nisrina Alifah , Naia Nisrina Alifah , Ariyanto Khansa Salsabila Putri , Nazilah Yasmin
Published: January 2024

Introduction : Quarter life crisis is an individual's response to moving towards the reality of life in which there is instability, continuous change, various choices and the emergence of panic due to feeling helpless. Life changes like this are accompanied by the emergence of various kinds of emotional reactions such as anxiety, panic, stress, and confusion about goals, as well as doubts about one's own abilities and fear of failure. Methods: in utilizing social media, using qualitative methods, which include collecting data by interviews and delivering material. Purpose: to take an approach involving visual narratives, interviews, and practical solutions in providing a comprehensive view of the quarter life crisis and providing positive value in using social media and having a good impact on oneself. Results: The author's video has its own interest among Instagram users, as evidenced by the author's video views reaching 3,753 and video likes reaching 89 likes. This shows that Instagram users gain knowledge about the quarter life crisis. Conclusion: Currently there are still students who experience changes in emotional reactions such as anxiety, panic, stress, and confusion and doubt about their own abilities. Video about the quarter life crisis by conducting interviews with students to get various perspectives on the quarter life crisis and strategies for dealing with it. The video content will be disseminated via social media such as Instagram.
Memahami Tantangan Shadow Teacher di SLB Rumah Kita Kota Batam
Authors: Ellyzabeth Sinaga  , Desetina Harefa  , Dewi Lidya S  , Riyana Laia  , Agatha Pebrian M Naibaho
Published: January 2024

Sekolah Luar Biasa Rumah Kita adalah lembaga pendidikan untuk anak berkebutuhan khusus yang mengalami masalah dalam memperoleh pendidik dan shadow teacher. Kekurangan pendidik dan shadow teacher menjadi permasalahan yang cukup mendesak untuk di selesaikan. Program studi Pendidikan Kristen Anak Usia Dini melaksanakan Tridarma dan roadmap dengan menjalankan PKM berkualitas dengan program PKM yang menjalin kerjasama perguruan tinggi dengan instansi Pendidikan SLB Rumah Kita Batam dengan melakukan pendampingan pembelajaran di SLB Rumah Kita dalam kegiatan menjadi Guru ABK dan dengan Shadow Teacher dengan tujuan pengembangan SDM dengan luaran PKM berbentuk metode penelitian kualitatif deskripsi di Jurnal ilmiah dalam negeri dengan mengacu kepada spritualitas dan science and technology. Hasil yang diperoleh dari kegiatan PKM ditemukan yaitu peserta PMK yang terdiri dari satu kepala SLB,  dua guru, empat walimurid dan 20 anak berkebutuhan khusus yang dibagi menjadi dua kelas yaitu kelas SD atau SMPLB dan SMALB, berserta Tim PKM yang berjumlah dua puluh empat yang terdiri dari dua dosen dan dua puluh dua mahasiswa Angkatan II, Angkatan IV PK AUD STT Real Batam. PKM ini memberikan solusi masalah shadow teacher yang dibutuhkan di SLB Rumah Kita Batam menjalankan tugas sebagai pendidik sebanyak dua orang mahasiswa dan shadow teacher sebanyak 13 orang dengan melayani siswa sebanyak 13 anak didik, dengan hasil sangat baik yang diperoleh dari kepuasan pihak SLB Rumah Kita terhadap kinerja mahasiswa dalam pelaksanaan PKM tertuang dalam evaluasi kegiatan PKM, dari hasil evaluasi dapat diambil kesimpulan bahwa PKM yang dilakukan sangat membantu SLB Rumah Kita.
Workshop Prokantor, Kantoria, dan Organis di Jemaat GMIT Exodus Oefafi Klasis Kupang Timur
Authors: Victor Arnold  , Orista Mone  , Yuharni Timo  , Selvi Liow  , Niken Nomeni  , Gerlis Ludji Leo  , Elisyena Taopan  , Atni Misa
Published: January 2024

Jemaat GMIT Exodus Oefafi Klasis Kupang Timur adalah salah satu jemaat yang menjadi sasaran  tim Pengabdian masyarakat dan juga salah satu Jemaat yang mau untuk belajar dan terus belajar dalam membenahi diri sebagai gereja yang bernyanyi dan memuliakan nama Tuhan. Penataan dalam pelayanan setiap ibadah memiliki  tuntutan khusus yang harus dipenuhi yaitu penyajian pelayanan Musik Gereja yang baik. Para Pelayan perlu dipersiapkan sebelum tampil untuk memandu Jemaat dalam berbakti kepada Tuhan.  Musik memiliki peran yang sangat penting dalam gereja. Selain itu, mereka juga harus diberikan pemahaman tentang cara memimpin Jemaat dalam bernyanyi. Metode yang digunakan yaitu melalui pendampingan dan pelatihan dari ahli dalam bidang musik. Pengabdian masyarakat ini bertujuan untuk meningkatkan kemampuan dalam bermain alat musik dan juga kemampuan dalam membaca not dan memimpin paduan suara. Setelah dilakukannya pelatihan ini maka hasil dari kegiatan ini adalah adanya perubahan keterampilan dalam memainkan alat musik dan juga ketrampilan dalam memimpin jemaat bernyanyi dan memimpin paduan suara.
Bimbingan Konseling dalam Gereja untuk Mengatasi Kecanduan Game Online pada Anak Remaja
Authors: Titin Aritonang  , Novalina Manik  , Yenti Tamba
Published: January 2024

Di zaman era digital saat ini, banyak anak-anak yang kecanduan game online khususnya di kalangan para remaja. Kecanduan game online merujuk pada kondisi di mana seseorang mengalami ketergantungan yang kuat, akibat dari kecanduan bermain game online yang menimbulkan investasi ekstrim dalam bermain. Oleh karena itu, tulisan ini, akan mendiskusikan bagaimana bimbingan konseling dalam konteks gereja dapat menjadi pendekatan yang berdaya guna dalam mengatasi masalah kecanduan game online pada remaja. Dengan melakukan bimbingan konseling di gereja, maka remaja dapat mengubah cara ketergantungan mereka dalam bermain game online. Penelitian ini menggunakan metode penelitian kualitatif deskriftif dengan pendekatan kajian pustaka. Hasil yang diperoleh antara lain, para remaja yang kecanduan bermain game online berdampak pada berbagai aspek kehidupan remaja seperti kesehatan, psikologi, akademis, sosial, maupun keuangannya. Dengan pendekatan holistik yang mencakup aspek fisik, psikologis, sosial, dan spiritual, maka gereja dapat memberikan solusi yang komprehensif untuk membantu remaja mengatasi kecanduan game online.