bluuebunny/crossref_metadata_2025 huggingface dataset:
The overall correlation of quasar anomalies is the touch-stone of its valid theories

III.
Authors: Yang YunBiao
Published: January 2025

According to the idea formed in Paper 1, the root cause of the various strange phenomena of quasars is based on the quasar world, which is composed of anti-matter, a region that restricts the behavior of moving (anti-) particles in an anti-gravitational interaction. This idea is based on the entire correlation of quasar anomalies. It can be argued that this entire correlation is the key, even the touch-stone whether it is true or not, of any new physical theory to explain quasar phenomena. The existing theoretical framework of physics, which provides explanations for quasar anomalies, clearly does not have this entire correlation. Therefore, the overall anomaly of quasars shows that our physical framework is no longer suitable for describing that distant world. Only under the framework of a reasonable new theory can the various strangeness of quasars be restored to normal! Qualitative theoretical analysis shows that in the real environment of superluminal motion, various anomalies of quasars (only caused by subluminal physical perspective) are not only normal, but also mutually consistent. Astronomical observations have shown that in the quasar world, the separation of various high-energy and dense structures has become the majority, which does not conform to the basic logic of the establishment of supermassive balck holes (SMBH). The source of quasar energy, explained by the existing SMBH accretion disk model, also has obvious flaws. Under the theoretical framework of faster-than-light physics, the anti-matter celestial model has basically reached the entire correlation with the faster-than-light structure separation phenomenon, energy mode (luminance mystery) and unilateral jet mode of quasars.
Ambiguous Justice: Native Americans and the Law in Southern California, 1848-1890
Authors: Gunther Vanessa Ann
Published: January 2025

In 1769, Spain took action to solidify control over its northern New World territories by establishing a series of missions and presidios in what is now modern California. To populate these remote establishments, the Spanish crown relied on Franciscan priests, whose role it was to convince the Native Californian population to abandon their traditional religious practices and adopt Catholicism. During their tutelage, the Indians of California would be indoctrinated into Spanish society, where they would learn obedience to the church and crown. The legal system of Southern California has been used by Anglo populations as a social and demographic tool to control Native Americans. Following the Mexican-American War and the 1849 Gold Rush, as California property values increased and transportation corridors were established, Native Americans remained a sharply declining presence in many communities, and were likely to be charged with crimes. The sentences they received were lighter than those given to Anglo offenders, indicating that the legal system was used as a means of harassment. Additionally, courts chronicled the decline of the once flourishing native populations with each case of drunkenness, assault, or rape that appeared before the bench. Nineteenth-century American society had little sympathy for the plight of Indians or for the destruction of their culture. Many believed that the Indians of Southern California would fade from history because of their inability to adapt to a changing world. While many aspects of their traditional culture have been irreparably lost, the people of southern California are, nevertheless, attempting to recreate the cultures that were challenged by the influx of Europeans and later Americans to their lands.
The Daring Trader: Jacob Smith in the Michigan Territory, 1802-1825
Authors: Crawford Kim
Published: January 2025

A fur trader in the Michigan Territory and confidant of both the U.S. government and local Indian tribes, Jacob Smith could have stepped out of a James Fenimore Cooper novel. Controversial, mysterious, and bold during his lifetime, in death Smith has not, until now, received the attention he deserves as a pivotal figure in Michigan’s American period and the War of 1812. This is the exciting and unlikely story of a man at the frontier’s edge, whose missions during both war and peace laid the groundwork for Michigan to accommodate settlers and farmers moving west. The book investigates Smith’s many pursuits, including his role as an advisor to the Indians, from whom the federal government would gradually gain millions of acres of land, due in large part to Smith’s work as an agent of influence. Crawford paints a colorful portrait of a complicated man during a dynamic period of change in Michigan’s history.
A pecuária no Brasil e em Goiás: retratos do Censo Agropecuário 2017
Authors: Silva Edson Batista da
Published: January 2025

Este texto analisa os dados do Censo Agropecuário-2017, especificamente as variáveis de produção pecuária segundo distintos grupos de área. Para tanto, utilizou-se de pesquisa bibliográfica, documental e da internet. Os resultados demonstram a eficiência e a eficácia dos pequenos estabelecimentos agropecuários. Neles, apesar do menor domínio de terras, se concentram a criação de animais de distintos ramos da pecuária. Os grandes edifícios rurais não são sinônimo de produção imponente, a despeito da alta concentração de áreas. Os grupos sem área, facilmente nomeados de grupos sem-terra, sinalizam assentimento do Estado com sujeitos sociais desterrados. Eles, mesmo nestas condições, desenvolvem atividades produtivas. Os médios estratos também têm algum vulto nos ramos da pecuária. Depreende-se a perpetuação no Brasil da terra utilizada como reserva de valor, reserva patrimonial e o descumprimento da função social da terra. Igualmente, a urgência da reforma agrária, o estabelecimento de um limite de propriedade, com democratização do direito à terra e ao território, para garantia da justiça social, distribuição de renda e democratização do campo brasileiro.
Smíšené instrumenty a zákaz použití některých druhů zbraní za ozbrojených konfliktů
Authors: Ondřej Jan
Published: January 2025

Mixed instruments combine the elements of disarmament law and humanitarian law. The concept of disarmament embraces a partial or complete reduction and elimination of weapons and armed forces. Disarmament defined in the broad sense includes a range of measures which do not lead to the act of giving up weapons in itself, but facilitate their reduction or modification, restrict proliferation of weapons, their tests, etc. In principle, disarmament is based on political aspects.
On the other band the aim of humanitarian law in the broad sense is the protection of victims of armed conflicts, prohibition of specific methods and means of warfare, etc. There are several international treaties which include disarmament and humanitarian aspects – The Chemical Weapons Convention of 1993, The Anti-Personnel Mines Convention of 1997, The Convention on Cluster Munitions of 2008. Some elements of both areas of international law are included in The Biological Weapons Convention of 1972 (disarmament convention) and The Certain Conventional Weapons Convention of 1980 (humanitarian law convention). As for the prohibition of weapons, the most efficient way would be to impose an unconditional ban. For example, only a complete ban on anti-personnel mines would substantially prevent their indiscriminate effects and profound destructive impacts on civilian population.
Isolation, identification, and in silico characterisation of antimicrobial peptides from mangrove plants, Suaeda nigra and Suaeda maritima
Authors: Gathala R P , Yamini U , Gudivada M
Published: January 2025

Infectious diseases continue to be the primary cause of death, representing a significant public health issue globally. While antibiotics are an effective remedy, bacterial infections have developed resistance to these drugs, resulting in antibiotic treatment failure. Hence there is a quest for novel antibacterial agents from natural sources, including plants and other creatures. Plants possess the tendency to synthesise substances to defend themselves from challenging surroundings. This has prompted the investigation of antimicrobial peptides that are commonly derived and possess strong efficacy against pathogens. Moreover, the utilisation of mangroves in traditional medicine is garnering significant attention due to its reputation as an exceptional reservoir of bioactive substances for the treatment of cancer, diabetes, and others. Therefore, the current study concentrated on identifying the antimicrobial peptides from Suaeda nigra and Suaeda maritima. The analysis of leaf proteomes in S. nigra and S. maritima showed that the 15 and 20 KDa peptides exhibited strong antimicrobial activity, which were identified as Alpha-2-purothionin precursor and Vicin-like antimicrobial peptides-2-2-like proteins. The physicochemical characterization of Alpha-2-purothionin and Vicin-like antimicrobial peptides shows respective molecular weights of 14557.8 and 16353.78 Da. As well as their pI values were calculated as 5.13 and 6.11. The 3D structural analysis revealed that the Alpha-2-purothionin precursor and Vicin-like antimicrobial peptides showed an accurate model more similar to the templates PDB ID: 1nbl and PDB ID: 1fxzA. This study concluded that the identified proteins have significant antimicrobial potential against bacterial and fungal species, and their predicted structures were reliable.
Medale Stefana Batorego. Uwagi ikonograficzne
Authors: Rokita Jan Gustaw
Published: January 2025

The author of this paper discusses twenty-six works of art, including medals, coins, portrait engravings, emblems as well as specimens of woodcarving and sculpture. Apart from a detailed analysis of the medallic legacy of Stefan Batory, the aim of this study is to find and describe works of art that a medallic artist might have been exposed to when commissioned by the king or his immediate circle to fashion a medal. Having identified direct sources of inspiration for seventeenth-century artists, it has been possible to offer a better explanation of how Stefan Batory promoted his own indisputable political or military achievements.
The Category of Strangeness in the Jewish Tradition
Authors: Szczerbiński Waldemar
Published: January 2025

The phenomenon of strangeness seems to be a timeless and universal problem. The feeling of alienation was especially experienced by the Jews living in the diaspora. However, the aim of this article is not to discuss the attitude of other nations towards Jews as strangers but, on the contrary, to show the attitude of Jews towards non-Jews in the biblical, rabbinic, modern and contemporary context. The analyses of the category of strangeness seem to be particularly relevant and significant in the context of the ongoing war in Israel.
Alegoria szczęśliwego panowania pędzla Jana Reisnera z łazienki ogrodu włoskiego zamku w Żółkwi
Authors: Kossowski Maciej Dariusz
Published: January 2025

Jan Reisner’s painting from the castle in Żółkiew has been referred to on several occasions in art history literature, but the personifications depicted there were erroneously identified. In this paper, the author challenges the assertions made earlier. An iconographic analysis combines all elements of the composition into a coherent whole, thus revealing novel, hitherto unknown symbolism of the representation. The painting allegorically anticipated the state of affairs in the country after king Jan III’s return from the autumn campaign of 1684, while the choice of theme demonstrates the painter’s in-depth knowledge of antiquity, which he drew on when creating the work. Also, the allegorical import of the piece dictated where the painting would be exhibited, as the location was anything but insignificant. The painting was placed in the baths of the Italian garden of the king’s residence in Żółkiew, and hung in the middle room above the bed, as stated in the inventory of 1726, a fact established and reported for the first time in this study. These new findings have raised the cultural and artistic value of the work.
UNLOCKING THE POTENTIAL: MEDIATING EFFECT OF CUSTOMER ENGAGEMENT AND ONLINE SHOPPING MOTIVATION ON MMO PLAYERS' WILLINGNESS TO PAY MORE
Authors: Çam Selim
Published: January 2025

This study aims to investigate the effect of MMO players' addiction levels on their willingness to pay. It examines this effect by mediating online shopping motivation and customer engagement variables. The impact of environmental factors on willingness to pay, even when the level of dependency remains fixed, has been investigated with online shopping motivation and customer engagement. We collected data on the attitudes and perceptions of online game participants through a questionnaire. Data suitable for the study were obtained from 772 people. According to this sample size, the power of the study was calculated as 96.5%. After the participants' demographics were explained, the analyses were performed with SEM. The results confirm that willingness to pay is affected by the level of online game addiction. Among online shopping motivations, early adoption, stimulation-seeking, and customer engagement variables, both separately and together, increase consumers' willingness to pay. This paper provides a clear view on behaviour of an increasing number of online gamers by examining the purchasing and payment behaviour of MMO players.
TURKISH BANKS' NON-INTEREST INCOME AND THE IMPACT OF THE CBRT REGULATIONS
Authors: Demirboğa Olcay , Şengül Aykut
Published: January 2025

Banks, which serve to facilitate the transfer of funds between deficit and surplus positions, seek to maximize their income in order to maximize their profits. In order to achieve this, banks attach great importance to the generation of non-interest income as well as interest and fee income, which represent their primary sources of revenue. In this study, we analyze the impact of potential determinants of non-interest income in the Turkish banking sector on non- interest income using a panel data set. Accordingly, this study analyses the determinants of non-interest income in the Turkish banking sector using a data set of 19 banks and 11 years. The analysis demonstrates that bank-specific variables, including the net interest margin, loans-to-assets ratio, asset growth rate, capital adequacy ratio, return on equity, and the inflation rate, significantly and negatively impact non-interest income. In contrast, changes in the return on assets and gross domestic product have a positive and significant effect on primary income. Furthermore, the CBRT's regulations on fees, charges and commissions in 2020 are anticipated to influence the non-interest income ratio of the Turkish banking sector, particularly that of public banks. Moreover, the study may also contribute to the academic literature on potential regulatory policies that could impact the primary income of banks.
KADIN İSTİHDAMINI ETKİLEYEN EKONOMİK VE MALİ FAKTÖRLER: TÜRKİYE GENELİ VE SEGE BÖLGELERİ İÇİN PANEL VERİ ANALİZİ
Authors: Akgül Yılmaz Gülay , Nalbant Efe Gözde
Published: January 2025

Türkiye’de 2023 yılı itibarıyla %31,3 olan kadın istihdam oranının çok düşük düzeylerde olduğu gerek %65,7 olan erkek istihdam oranı ile gerekse %51,1 olan OECD ülkeleri kadın istihdam ortalaması ile kıyaslandığında net bir şekilde görülmektedir. Nüfusun yarısını oluşturan kadınların istihdam oranının artırılması kadınların güçlendirilmesinin yanı sıra toplumun ve ekonominin güçlenmesi başka deyişle kalkınma ve ulusal refah açısından önem arz etmektedir. Bu çalışmanın amacı, Türkiye’de kadın istihdamını artırıcı kamu mali, ekonomik ve sosyal politikalarına yön verecek şekilde kadın istihdamı üzerinde etkili olduğu kabul edilen ekonomik ve mali faktörlerin gerek Türkiye ölçeğinde gerekse Sanayi ve Teknoloji Bakanlığı tarafından oluşturulmuş Sosyo Ekonomik Gelişmişlik Endeksine (SEGE) göre belirlenen dört alt bölge itibarıyla etkilerini ortaya koymaktır. Analizlerde, mali alana ilişkin kişi başına düşen vergi ile kişi başına düşen eğitim ve sağlık harcamalarına yer verilerek, kadın istihdamını artırmada mali politika araçlarının etkileri, bireysel vergi yükü ve beşeri sermayeyi geliştirmeye yönelik kamu harcamaları perspektifinden ortaya koyulmaya çalışılmıştır. 2009-2020 dönemi İBBS Düzey-2 verileri ile önce Türkiye geneli için gerçekleştirilen analiz daha sonra dört SEGE bölgesinin her biri için tekrarlanmıştır. Böylece farklı sosyoekonomik gelişmişlik düzeyine sahip her bir bölgede kadın istihdamının artırılması yönünde etkili olan faktörler belirlenerek bölgesel düzeyde farklılaştırılmış politika ve uygulamaların gerçekleştirilebilmesine yönelik bulgular ortaya koyulmaya çalışılmıştır.
Law and Economics Scholarship in Malaysia
Authors: Khong Dennis W. K. , Kong Erica X.W.
Published: January 2025

This article reports law and economics activities from Malaysia or by Malaysians. It surveys the resulting literature and identifies selected personalities who have contributed to advancing law and economics research in Malaysia. Other past activities, such as organising an online conference for the Asian Law and Economics Association in 2020, are recounted. It notes the extent to which Malaysian universities offer law and economics courses. The Malaysian government’s requirement for regulatory impact statements is the right direction to instill further interest in law and economics in government officers. Finally, some existing challenges and opportunities for future development are examined for future actions.
Sustainability as a business opportunity: a corpus-assisted discourse analysis of sustainable finance discourse
Authors: Nervino Esterina , Lan Ge , Cheung Joyce Oiwun
Published: January 2025

As sustainability becomes increasingly embedded in the practices of financial institutions worldwide, financial discourse is also adapting to reflect the new related societal values. This study aims to identify the discursive strategies employed by banks to frame their leadership in sustainability, present their sustainable products and services as business opportunities, and explore the development of dialogic relationships between banks and clients. Employing a corpus-assisted discourse analytical approach, a dataset of 2 million words comprised of sustainability-related reports publicly available on banks’ websites was analysed. The findings indicate a growing recognition of the significance of diversity and inclusion in senior leadership positions, with an observed increase in the representation of women. Moreover, banks position themselves as service providers and catalysts for transforming associated risks into business opportunities, leveraging various factors such as financial success, positive culture, and strong support for customers and employees. In terms of the bank-client relationship, the findings reveal a shift towards empowering clients and acknowledging their agency, encouraging them to make informed decisions and take charge of their financial well-being. This research sheds light on the evolving discursive practices within the realm of sustainable finance and provides valuable insights for both academia and the business sector.
Leveraging mutually shared knowledge through translanguaging in EMI classrooms: combining multimodal conversation analysis with interpretative phenomenological analysis
Authors: Tai Kevin W. H. , Li Linhong
Published: January 2025

Recent research has examined how teachers utilize translanguaging to tap into students’ out-of-school knowledge and students’ prior learnt content knowledge to scaffold students’ learning of new content knowledge. This study addresses a research gap by examining how teachers can maximize the utilization of mutually shared knowledge, which is not accessible to individuals outside the classroom community, through translanguaging to consolidate students’ content learning. The data is derived from a larger project conducted in Hong Kong secondary English-Medium-Instruction mathematics classrooms. Multimodal Conversation Analysis (MCA) is employed to analyse classroom interactions, triangulated by video-stimulated-recall interviews analysed with Interpretative Phenomenological Analysis (IPA). We argue that establishing a translanguaging space allows teachers to capitalize on the shared sociocultural knowledge intrinsic to classroom communities, which shapes content instruction and forges meaningful relationships with students. We also highlight the significance of combining MCA with IPA to gain a deeper understanding of specific translanguaging moments and the reasoning behind incorporating mutually shared sociocultural knowledge into classroom interactions, which cannot be attained solely through the description of interactional sequences.
Gene mining, recombinant expression and enzymatic characterization of N-acetylglucosamine deacetylase
Authors: Qiu Min , Dai Xiaohui , Hu Jiliang , Zhang Jianlong , Liu Qiang , Luan Jiabao , Zhou Qingmei , Xia Yu , Zhang Kunxiao , Liu Weiwei
Published: January 2025

Objectives

Glucosamine (GlcN) is an important bioactive substance that is widely used in medicine, dietary supplements, cosmetics, and other fields. The traditional method of producing GlcN is mainly through chitosan hydrolysis catalyzed by strong acid, but this process is usually accompanied by environmental pollution and high energy consumption. Therefore, the development of green and efficient production methods of glucosamine has become the focus of current research.

Methods

In this study, N-acetylglucosamine (GlcNAc) was used as the substrate to facilitate the enzymatic synthesis of GlcN by deacetylase. Four deacetylases (TkDAc, PkDAc, PpDAc and AbDAc) were selected from marine thermophilic microorganisms, and Escherichia coli (E. coli) was used as the host for recombinant expression.

Results

The soluble expression of PpDAc was poor, so several groups of solubilizing labels were tried, and the results showed that the soluble expression of recombinant plasmid ArsC-PpDAc carrying pro-solubilization labels was greatly improved.

Conclusions

The effects of temperature and pH on enzyme activity were investigated by single factor analysis. Kinetic parameters further revealed that ArsC-PpDAc exhibited the highest catalytic activity, with a Kcat/Km value of 7.29, and achieved a conversion rate of over 95 %. The condition of ArsC-PpDAc was optimized, and the results showed that ArsC-PpDAc showed good tolerance to organic solvents, and its catalytic activity was not significantly affected.
Scaling of ventral hippocampal activity during anxiety
Authors: Cerquetella Carlo , Gontier Camille , Forro Thomas , Pfister Jean-Pascal , Ciocchi Stéphane
Published: January 2025

The hippocampus supports a multiplicity of functions, with the dorsal region contributing to spatial representations and memory, and the ventral hippocampus (vH) being primarily involved in emotional processing. While spatial encoding has been extensively investigated, how the vH activity is tuned to emotional states, e.g. to different anxiety levels, is not well understood. We developed an adjustable linear track maze (aLTM) for male mice with which we could induce a scaling of behavioral anxiety levels within the same spatial environment. Using in vivo single-unit recordings, optogenetic manipulations and population-level analysis, we examined the changes and causal effects of vH activity at different anxiety levels. We found that anxiogenic experiences activated the vH and that this activity scaled with increasing anxiety levels. We identified two processes that contributed to this scaling of anxiety-related activity: increased tuning and successive remapping of neurons to the anxiogenic compartment. Moreover, optogenetic inhibition of the vH reduced anxiety across different levels, while anxiety-related activity scaling could be decoded using a linear classifier. Collectively, our findings position the vH as a critical limbic region that functions as an ‘anxiometer’ by scaling its activity based on perceived anxiety levels. Our discoveries go beyond the traditional theory of cognitive maps in the hippocampus underlying spatial navigation and memory, by identifying hippocampal mechanisms selectively regulating anxiety.

Significant statementThis study reveals how the ventral hippocampus (vH) functions as an "anxiometer", tuning its activity to different anxiety levels. Using an adjustable linear track maze (aLTM) for mice, we demonstrated that vH activity scales with increased anxiety. By recording single-neuron activity and performing optogenetic manipulation of vH during the aLTM task, we identified key neuronal mechanisms for neuronal scaling during anxiety. Additionally, a linear classifier was used to highlight anxiety-related activity scaling. Our findings advance the understanding of hippocampal function beyond spatial navigation and memory, offering new insights into how the brain regulates anxiety at the neuronal level.
E-Learning-Based Collaborative as an Effort to Reduce High School Students' Misconceptions of Heat
Authors: Haryono Heny Ekawati , Jatmiko Budi , Prahani Binar Kurnia , Zayyadi Moh. , Kaniawati Ida , Kurtuluş Muhammed Akif
Published: January 2025

The purpose of this study was to determine the effect of E-learning-based collaborative learning in reducing students' misconceptions about class heat material. This study used a pre-experimental design with a one-group pretest-posttest design. The sampling technique used purposive sampling. The sample used was 300 grade XI high school students. Student misconceptions were analyzed using the CRI (Certainty of Response Index) method. The results showed that student misconceptions decreased by 26.50% from an average of 54.00% before learning to 27.50% after implementing E-learning-based collaborative learning. Based on the results of the hypothesis test, it can be concluded that e-learning-based collaborative learning has proven effective in reducing high school students' misconceptions regarding the concept of heat. The novelty of this study lies in the integration of cooperative learning with an e-learning platform that is specifically designed to reduce misconceptions about the idea of heat at the Senior High School.
Development of Solar System Teaching Aids with Manipulative Virtualization Concrete and Digital Augmented Reality
Authors: Wiyanto Wiyanto , Miftakhul Falah Muhammad , Ardian Awaluddin  , Muhammad Sholikhan
Published: January 2025

Teaching aids are used to explain the concept of science learning in the form of real objects. Along with the development of Information and Communication Technology (ICT), the specifications for teaching aids need innovation, especially digital access and Augmented Reality (AR) based virtualization, which are currently growing rapidly. This research aims to develop a solar system teaching aids with manipulative virtualization concrete and digital AR. The ADDIE Research and Development (R and D) model has been applied to achieve the objectives of this study. The stages of this research were carried out through the stages of Analysis, Design, Development, Implementation and Evaluation. This research has produced a solar system teaching aids with manipulative virtualization concrete and digital AR. The results of the validation of content experts are 88%, validation of media and technology experts are 86% and teacher or user responses are 88%. The three validations reached the very feasible criteria. The average percentage of the validation score is 87.33% or the criteria are very feasible. It is concluded that the solar system teaching aids with manipulative virtualization concrete and digital AR are valid to be used in science learning to improve the science concepts comprehensions, especially solar system.
A very low carbohydrate diet improved metabolic profile in congenital generalized lipodystrophy type 4
Authors: Chakraborty Sayantan , Roy Subhankar , Das Debaditya , Chatterjee Sayantani , Sahana Pranab Kumar , Mukhopadhyay Satinath
Published: January 2025

A 17-year-old girl presented with recurrent attacks of acute pancreatitis, associated with severe hyperglycemia and hypertriglyceridemia, despite being on intensive insulin therapy for the last 10 years. She had severe acanthosis nigricans, generalized loss of subcutaneous fat and prominent veins over extremities. The serum levels of glucose and triglyceride did not reduce significantly, even with maximally tolerated doses of metformin (2 g), pioglitazone (45 mg) and fenofibrate (160 mg), not uncommonly seen in poor rural families in West Bengal, India. A detailed dietary recall revealed a very high carbohydrate intake (70% of total calorie) with very low protein and fat intake. A switch to a very low carbohydrate (30% of total calorie) diet led to a remarkable improvement in glucose and lipid profiles (the daily insulin requirement came down by 50% and triglyceride level came down to 600 mg/dL from 950 mg/dL). A whole-exome sequencing study confirmed congenital generalized lipodystrophy type 4. A carbohydrate restriction strategy may improve difficult-to-control glycometabolic profile in lipodystrophic subjects on high-carbohydrate diet.

Learning points

Lipodystrophy should be suspected in patient presenting with hyperglycemia, hypertriglyceridemia and low BMI.

A very low carbohydrate diet (30% of total daily calorie intake) may significantly improve glucose and lipid profiles in patients with lipoatrophic diabetes.

Blood glucose may be the most important initial step to control hypertriglyceridemia and risk of pancreatitis in this group of patients.
ИЗМЕНЧИВОСТЬ НЕКОТОРЫХ СЧЕТНЫХ ПРИЗНАКОВ И ПОЛИМОРФИЗМ ФРАГМЕНТА МИТОХОНДРИАЛЬНОЙ ДНК, ВКЛЮЧАЮЩЕГО ГЕН ND1, СИГОВ ГРУППЫ COREGONUS LAVARETUS SENSU LATO ИЗ ВОДОЕМОВ СЕВЕРА ЕВРОПЫ
Authors: СЕНДЕК Д.С. , БОЧКАРЕВ Н.А. , ЗУЙКОВА Е.И. , НОВОСЕЛОВ А.П. , ТИТОВ С.Ф. , АЛЕКСЕЕВ М.Ю. , БОЗНАК Э.И. , ИЛЬМАСТ Н.В.
Published: January 2025

Филогеографический и морфологический анализы сигов Coregonus lavaretus Европы, уровень полиморфизма гена nd1 мтДНК свидетельствуют об относительно древнем происхождении некоторых популяций, населяющих водоемы западнее Ютландии. Высказывается предположение, что часть популяций в Европе представляют собой остатки первичной волны расселения основателей из Центральной Сибири (бассейн р. Лены). В более поздние волны миграций сигов из Сибири, синхронизированные по времени с событиями повторяющихся нижнечетвертичных оледенений, к западу от Урала расселялись они из нижнего течения крупных водотоков Западной Сибири (реки Обь, Енисей), которые эволюционировали относительно независимо от сигов из Центральной Сибири. В результате повторяющихся событий расселений из разобщенных приледниковых рефугиумов с востока и запада на географическом пространстве Восточной Европы от Балтийского моря до р. Печоры гаплотипы сигов оказались сильно перемешаны. Помимо естественно-исторических причин на картину распределения генетической изменчивости в природных популяциях сигов Восточной Европы в последние десятилетия оказали влияние рыбоводные мероприятия по акклиматизации и/или искусственному поддержанию отдельных популяций.

Phylogeographic and morphological analyzes of the whitefish Coregonus lavaretus of Europe, the level of polymorphism of the mtDNA nd1 gene indicate a relatively ancient origin of the populations inhabiting water bodies west of Jutland. It is suggested that these populations in Europe represent remnants of the primary wave of settlement by founders from Central Siberia (Lena River basin). In later waves of whitefish migrations from Siberia, synchronized in time with the events of repeated Lower Quaternary glaciations, whitefish settled west of the Urals from the lower reaches of large watercourses of Western Siberia (Ob River, Yenisei River), which evolved relatively independently of whitefish from Central Siberia. As a result of repeated events of settlement from disconnected periglacial refugia from the east and west, in the geographical space of Eastern Europe from the Baltic Sea to the Pechora River, whitefish haplotypes were greatly mixed. In addition to natural-historical reasons, the distribution of genetic variability in natural whitefish populations in Eastern Europe in recent decades has been influenced by fish hatchery activities for acclimatization and/or artificial maintenance of populations/species.
Jara, Margarita; Zariquiey, Roberto; Valenzuela, Pilar y Escobar, Anna María (Eds.). (2023). Spanish Diversity in the Amazon. Dialect and Language Contact Perspectives. Leiden: Brill
Authors: Diaz Romero Camilo Enrique
Published: January 2025

En el estudio de los fenómenos de lenguas en contacto en América del Sur, uno de los temas de interés se cimenta sobre la relación de las lenguas indígenas con las lenguas romances hegemónicas, vínculo que, a nivel histórico, lleva estableciéndose desde hace varios siglos (Triana y Antorveza, 1987). Si bien existen propuestas de un conjunto andino de variedades del español, que resultan de una destacada influencia de continuos dialectales del quechua (Arboleda, 2000; Andrade, 2019; Stewart, 2020), aún son escasos los reportes del contacto con lenguas de la Amazonía. En ese contexto, este libro ofrece un panorama inicial sobre los desarrollos emergentes de esto último mediante la exposición de estudios de investigadores que trabajan con comunidades residentes en Perú, Colombia y Ecuador.
Editorial 93 La importancia de la epistemología en la investigación en administración y organizaciones
Authors: Saavedra-Mayorga Juan Javier
Published: January 2025

Innovar es reconocida como una revista destacada en los campos de las ciencias sociales, la administración y la contabilidad en Iberoamérica. A diferencia de las revistas o magazines institucionales, que difunden los resultados de la investigación y la docencia que se realiza en determinadas facultades, universidades o asociaciones profesionales, esta es una publicación de carácter científico y por lo tanto está dirigida a una comunidad disciplinar e investigativa más amplia. De ahí que uno de nuestros principales criterios para la publicación de los artículos que ingresan al proceso de evaluación sea la validez científica de sus resultados.
Efectos financieros y creación de valor de las pymes durante la pandemia por COVID-19: un análisis desde los flujos de efectivo
Authors: Palacio Bran Isabel Cristina , Correa García Jaime Andrés , Correa Mejía Diego Andrés
Published: January 2025

La pandemia por covid-19 afectó a la población en general deteniendo casi por completo la economía a nivel global, por lo que es fundamental identificar las implicaciones organizacionales que tuvo a partir de las cifras contables. El propósito de este artículo es analizar el impacto financiero y la creación de valor ocasionado por la crisis de la covid-19 en las pymes de Colombia, a través del estado de flujos de efectivo (efe). Para ello, se utilizó una muestra de 11.908 pymes durante 2019 y 2020. Se aplicó la técnica de bootstrapping para calcular la diferencia de medianas de diversos indicadores financieros relacionados con el efe. Los resultados evidencian que el sector más afectado esta crisis fue el de servicios con mayor declive financiero; la diferencia de medianas muestra variaciones estadísticamente. significativas en sus actividades operacionales. Este trabajo aporta a la literatura académica, ya que evalúa el impacto financiero a partir del efe de las pymes colombianas durante una época de crisis empresarial, además de servir de apoyo a posteriores investigaciones o en la planeación de estrategias empresariales en tiempos de incertidumbre.
Intención de las organizaciones para implementar inversión socialmente responsable: un enfoque ampliado de la teoría del comportamiento planificado (TCP)
Authors: Almanza Junco Carlos Alberto , Pulido-Ramírez María del Pilar , Pascagaza Corredor Yefri Manuel
Published: January 2025

La inversión socialmente responsable (ISR) es fundamental para lograr la sostenibilidad empresarial. Este estudio examina los factores que influyen en la intención y el comportamiento de ISR en pymes de servicios colombianas, aplicando una extensión innovadora de la teoría del comportamiento planificado (TCP). Mediante un diseño no experimental, transversal y correlacional, se encuestó a 413 gerentes para analizar las relaciones entre actitudes, normas subjetivas y control conductual percibido. El modelo TCP se amplió con variables contextuales como presiones externas y facilitadores en la adopción de prácticas de ISR. Los resultados, obtenidos mediante modelado de ecuaciones estructurales (PLS-SEM), revelan que el control conductual percibido es el predictor más fuerte de las intenciones de ISR, seguido por normas subjetivas y actitudes. Adicionalmente, se descubrió que presiones externas y facilitadores influyen en la posterior adopción de comportamientos concretos de ISR. Sin embargo, su adopción responde más a presiones que a convicciones organizacionales siendo esta la principal limitante para adoptarlos. Este estudio confirma la utilidad de la TCP para examinar la adopción de ISR en empresas y destaca la relevancia de incorporar variables contextuales al modelo. La investigación contribuye significativamente a la comprensión de la ISR en economías emergentes y proporciona implicaciones prácticas para organizaciones y formuladores de políticas interesados en fomentar inversiones sostenibles.
Factores asociados al uso de la banca digital en pequeños agronegocios de la región central de Colombia
Authors: Romero-Sánchez Diego , Barrientos Fuentes Juan Carlos , Barrios Dursun
Published: January 2025

La implementación de servicios bancarios digitales ha traído consigo ventajas significativas para las organizaciones, entre las cuales se destacan la obtención de respuestas instantáneas, la capacidad de gestionar de manera autónoma los servicios y la reducción de tiempos y costos. A pesar de estos avances, el sector agrario representa una de las industrias con menor adopción tecnológica y limitada inclusión financiera. Por ende, el propósito de esta investigación se centró en identificar los factores vinculados a la adopción de la banca digital por parte de productores agrarios de la región central de Colombia. Para ello, se realizó un modelo de ecuaciones estructurales, lo que permitió determinar la intención de uso de la banca digital por medio de cinco variables latentes, evaluadas por medio de veinte variables observables. Se encontró que la expectativa de esfuerzo, la influencia social, las condiciones facilitadoras y el hábito afectan positivamente la intención de usar los servicios financieros digitales. Los productores agrarios perciben la banca digital como útil, cómoda, fácil de implementar y con influencia de su entorno social. La percepción positiva hacia la banca digital entre productores sugiere un potencial para mejorar eficiencia financiera y promover desarrollo rural e inclusión, requiriendo políticas de accesibilidad y capacitación.
Escenas de la vida bohemia de Henri Murger: arte y modus vivendi revolucionario
Authors: Farías Duque Luis Alberto , Salvarani Pometto Silvana
Published: January 2025

El presente artículo examina el primer tomo del texto Scènes de la vie bohème (1851) del autor francés Henri Murger, con el propósito de entender cómo esta obra recoge un ideal artístico y un modo de vida acontecido en París, a partir de la década de 1840, a través del cual se pone de manifiesto que la figura del artista entra en conflicto con los valores de la sociedad burguesa. Usando como respaldo teórico los estudios de Elme-Marie Caro (1871), Pierre Bourdieu (1997), Jaime Álvarez Sánchez (2003) y Walter Benjamin (2012), se plantea como hipótesis que el modus vivendi de los personajes de la novela constituye una fuerza de resistencia simbólica contra las características de la naciente sociedad de mercado.
Modern Marvel: The Otay River Bridge
Authors: Fister Gale Sarah
Published: January 2025

The Otay River Bridge, a 1-km-long (0.6 mi), four-lane highway that spans the Otay River Valley in San Diego County, Calif., was a proving ground for precast concrete segmental construction. The resulting bridge delivers exceptional quality and durability with beautiful lines at a reasonable cost, all while having minimal impact on the local environment.
Built using the balanced-cantilever method, the bridge is only the second in California to employ segmented precast concrete. This bridge won three 2008 PCI Design Awards, including Best Bridge with Spans More Than 150 Feet, the All-Precast Concrete Solution Award, and the Harry H. Edwards Industry Advancement Award.
Project Spotlight: Precast concrete enables rapid replacement of Minneapolis bridge
Authors:   Precast/Prestressed Concrete Institute
Published: January 2025

The new St. Anthony Falls Bridge opened to traffic on September 18, 2008, just 339 days after notice to proceed. The 10-lane interstate bridge is a major commuter route in Minneapolis, Minn., and provides the main trucking link through the state. The new 1223-ft-long (372.8 m) bridge features high-strength, high-performance concrete for the post-tensioned box girder superstructure with a precast concrete main span of 504 ft (154 m). Separate parallel structures carry northbound and southbound traf- fic, each comprising two box girders joined together to provide a 90 ft 4 in.–wide (28 m) deck. The team of Flatiron-Manson Joint Venture, with FIGG as the design engineer, was selected by Mn/DOT in a best-value process.
Project Spotlight: Students use beer, kite to erect concrete pyramid
Authors:   Precast/Prestressed Concrete Institute
Published: January 2025

In an attempt to prove the feasibility of using kites to move stones and beer to prepare the site, Maureen Cummings and Ed Van O’Linda, developers and pro- ponents of the theory; Gary McGavin, a professor of architecture at California State Polytechnic University, Pomona; and Doug Mooradian of the Precast/ Prestressed Concrete Manufacturers Association of California (PCMAC), among others, put the theory to test.
Effects of Age-specific Fertility Trends on Overall Fertility Trends: United States, 1990–2023
Authors: Driscoll Anne K , Hamilton Brady
Published: January 2025

This report examines the role of age-specific trends in fertility rates in the decline in the number of births and of general and total fertility rates.
ПРИСТРІЙ ДЛЯ АВТОМАТИЗОВАНОГО КОНТРОЛЮ МІРИ КИСЛОТНОСТІ ВОДИ У СИСТЕМІ ОХОЛОДЖЕННЯ
Authors: Удолатій В. Б.
Published: January 2025

Анотація. Стійкість енергетичного встаткування до агресивного впливу охолоджуючих речовин, в основному, забезпечується шляхом добору й використання корозійно-стійких матеріалів. В існуючих реаліях підвищення корозійної стійкості енергетичного встаткування можливо лише за умови правильної організаціїї процесу охолодження на підґрунті достовірного вимірювання достатньої та  необхідної кількості величин якості додаткової й циркуляційної води. Тобто параметрів, які характеризують процеси відкладань на теплопередаючих поверхнях і корозії. Обґрунтовано вдосконалення схемотехнічного рішення датчику визначення міри кислотності охолоджувальної води.  Науково-технічне завдання, яке створено запитом практики, вирішується тим, що пропонований волоконно-оптичний рН-метр, що складається з основи,  віддзеркалюючого шару, основного світловоду, коаксіального світловоду з літієвого скла, первинного та вторинного розгалужувачів, електрооптичних фільтрів, джерело та фотоприймача випромінювання. Основна відмінність від найближчого аналога полягає у застосуванні  основного світловоду револьверного типу.Застосування револьверного світловода у сполученні з оболонкою з літієвого скла дасть змогу у рН-метрі пропонованої конструкції досягти більшої величини чутливості, компенсацію впливу дестабілізуючих факторів за рахунок використання ідентичних матеріалів та збільшення діапазону вимірів величини кислотності середовища. Впровадження до складу суднових інформаційно-вимірювальних систем запропонованого рН-метра дозволить адекватно й вірогідно оцінювати кількісні параметри охолодної води та створювати умови для їх раціонального технічного використання і діагностування об'єктів суднової енергетичної установки.
Specific immunohistochemical expression of Mmp-26 in prostatic adenocarcinoma
Authors: SILVA ROMILDO LUCIANO DA , PAES FRANCISCO LUÍS A. , SILVA SANDRA MARIA S. DA , SANTOS FABIANO , SANTANA EDUARDA S. DE , SILVA NETO JACINTO DA C.
Published: January 2025

Abstract Matrix metalloproteinases (MMP) have been identified as biomarkers for several diseases, including cancer. The increase in the expression of these enzymes has been related to greater tumor aggressiveness. MMP-26 is expressed constitutively in the endometrium and some cancer cells of epithelial origin. However, there is a lack of studies on its expression on prostatic carcinoma. In this study, the evaluation of MMP-26 reactivity by immunohistochemistry (IHC) was carried out in 150 paraffinized samples representative of benign and malignant prostatic lesions. 70 of the 150 samples showed IHC immunopositivity, being more prevalent in carcinoma cases (44 out of 70 cases) with moderate and strong intensity. The expression and intensity of the MMP-26 reaction showed a significant association with total PSA values. As expected, serum PSA levels were higher in cases of carcinoma than in prostatic hyperplasia or atrophy. Studies have demonstrated the potential of MMP-26 as a tumor marker, and our results have shown that its immunoexpression was useful to differentiate a group of benign and malignant samples in prostate tumors. This characteristic can assist in the predictive assessment and, consequently, in the development of new strategies for the diagnosis, prognosis, and treatment of prostate cancer.
Morphometric analysis of extraocular muscles and proptosis by computed tomography in Graves’ orbitopathy
Authors: Watanabe Erika Mayumi , Cavazzana Ronan Yudi , Ribeiro Douglas de Aguiar Manso , Brandão Lorena Candido , Haddad Ana Victória , Corrente José Eduardo , Trindade André Petean , Jorge Eliane Chaves
Published: January 2025

Abstract Objective: To assess the prevalence of changes on computed tomography (CT) in Graves’ orbitopathy (GO) and to correlate those changes with disease activity, as well as with clinical and biochemical variables. Materials and Methods: This was a retrospective study, conducted at a tertiary hospital, of clinical, biochemical, and imaging data from consecutive patients with GO who underwent at least one orbital CT scan between July 2012 and December 2020. A single observer quantified the thickness of the extraocular muscles and the degree of proptosis. Clinical and biochemical variables were analyzed to determine whether they correlated with CT changes, GO activity, and GO severity. Results: Our sample included data from 67 patients with GO (134 orbits), 50 (74.6%) of whom were female. There were positive correlations between the clinical activity score and increase in thyroid-stimulating factor/free thyroxine, between the severity of GO and the increase in the thickness of the extraocular muscles, and between the degree of proptosis and muscle thickness. Conclusion: Orbital CT proved effective in detecting thickening of the extraocular muscles and proptosis in patients with GO, changes that correlated significantly with clinical and biochemical variables. Muscle thickening was associated with the severity of GO and could be a biomarker of the risk of vision loss.
Non-neoplastic and neoplastic scrotal pathologies on magnetic resonance imaging: a pictorial essay
Authors: Caetano Thiago de Oliveira , Schuch Alice , Pedrollo Ivan Morzoletto
Published: January 2025

Abstract Magnetic resonance imaging is an essential tool for the assessment of the scrotum, particularly in cases with inconclusive ultrasound findings. It has a great capacity to differentiate between intratesticular and extratesticular lesions, as well as between neoplastic and non-neoplastic lesions. By providing an accurate characterization of lesions, magnetic resonance imaging plays a crucial role in preoperative tumor staging and decision-making. This pictorial essay highlights the key non-neoplastic and neoplastic testicular pathologies, as evaluated by magnetic resonance imaging. The recognition of these pathologies underscores the role the radiologists play in the care of patients with scrotal lesions, by providing an appropriate evaluation of the relevant imaging characteristics.