bluuebunny/crossref_metadata_2025 huggingface dataset:
UNIVERSITY STUDENTS’ ONLINE FOOD DELIVERY (OFD) USAGE INTENTION: INVESTIGATING THE ROLE OF SENSORY MARKETING AND PERCEIVED BENEFITS
Authors: Shun Han Kong , Abdul Rahman Abdul Rais , Tamby Chik Chemah , Jaafar Siti Nur’afifah
Published: July 2024

Background and Purpose: The increase of mobile phone usage in Malaysia had contributed to the increasing habit of purchasing food through online food delivery (OFD) service platforms. Sensory marketing is a conceptual strategy that helps to appeal to human five senses. It is utilized as promotion made on social media using ads or attractive photos in order to attract customers to order food through the social media platform. This study aims to investigate the role of sensory marketing (sight and touch) and perceived benefits (convenience and product variety) to predict university students’ online food delivery (OFD) usage intention.
 
Methodology: Structural equation modelling is used to accomplish the objectives of this study with the analyses of 400 university students who were surveyed through Google form application.
 
Findings: The findings concluded that both sensory marketing and perceived benefits influence university students’ OFD usage intention. The strongest predictor of OFD usage intention among students is ‘touch’ element representing sensory marketing followed by convenience (perceived benefits), product variety (perceived benefits) and sight (sensory marketing).
 
Contributions: The findings contribute to the relevant literature by improving the knowledge of online food delivery (OFD) usage intention and it may be beneficial to the foodservice providers for continuous improvement of their business.   
 
Keywords: Sensory marketing, perceived benefits, online food delivery app.
 
Cite as: Shun Han, K., Abdul Rais, A. R., Tamby Chik, C., & Jaafar, S. N. (2024). University students’ online food delivery (OFD) usage intention: Investigating the role of sensory marketing and perceived benefits. Journal of Nusantara Studies, 9(2), 297-317. http://dx.doi.org/10.24200/jonus.vol9iss2p297-317
CHINESE HIGH-PERFORMING UNIVERSITY STUDENTS’ SELF-EFFICACY AND SELF-PRIDE IN LEARNING ENGLISH AS A FOREIGN LANGUAGE
Authors: Liu Meihua , Liu Junxia
Published: July 2024

Background and Purpose: Both self-efficacy and self-pride play an important role in second/foreign language learning. Yet, they have seldom been researched simultaneously in the same context in relation to language learning. The current study aimed to examine Chinese high-performing university students’ English learning self-efficacy and self-pride and their predictive effects on the students’ English performance.
 
Methodology: 520 Chinese high-performing university students completed the 5-item Self-Pride Scale, the 3-item English Learning Self-Efficacy Scale and a background questionnaire, 14 of whom were interviewed.
 
Findings: Major findings were: a) the participants generally had a high level of English learning self-efficacy and self-pride, b) female students had significantly greater English learning self-efficacy and self-pride, c) English learning self-efficacy was significantly positively correlated with self-pride, d) both English learning self-efficacy and self-pride were significantly positively correlated with and predicted the students’ English performance, and e) the participants identified several causes for their English learning self-efficacy and self-pride.
 
Contributions: This study was one of the few that explored the relationship between English learning self-efficacy and self-pride and their predictive effects on students’ English performance. The findings thus provide insights for developing self-efficacy and self-pride in students to improve their learning of a second/foreign language.
 
Key words: Self-efficacy, self-pride, English performance.
 
Cite as: Liu, M., & Liu, J. (2024). Chinese high-performing university students’ self-efficacy and self-pride in learning English as a foreign language. Journal of Nusantara Studies, 9(2), 420-440. http://dx.doi.org/10.24200/jonus.vol9iss2pp420-440
DEALING WITH LANGUAGE VARIATION IN A SOURCE TEXT: MALAY SKETCHES AND ITS MALAY TRANSLATION
Authors: Haroon Haslina
Published: July 2024

Background and Purpose: Although translation generally involves the transfer of meaning from the source language (L1) to the target language (L2), it may also involve a third language or L3, that is, any other language(s) found in either the source or target text. Language variation in a source text presents a challenge to translators, as they need to deal with both L1 and L3. This paper aims to explore the issue of language variation in a source text to see how L3 is rendered in translation. More specifically, the aim is to explore how L3 segments in French, Latin and Italian in a text in English entitled Malay Sketches are dealt with when the text is translated into Malay, and to determine the effects resulting from the solutions taken by the translators.
 
Methodology: L3 in Malay Sketches are first identified. These L3 segments are subsequently mapped to their counterparts in the Malay translation, Gelagat & Ragam Orang Melayu. This mapping results in source language-target language pairs, which are then analysed to determine the solutions taken by the translators. These solutions are categorised based on the framework of translation solutions in L3 translation by Corrius and Zabalbeascoa (2011).
 
Findings: It was found that L3 translation generally involves substitution in which L3 is translated into Malay. Consequently, language variation, a defining feature of the source text, becomes invisible in the Malay translation.
 
Contributions: This study hopes to contribute to and expand current discourse on L3 in translation, especially in view of the fact that scant attention had been paid to L3 translation in Malaysia. 
 
Keywords: Malay Sketches, language variation, multilingual text, third language, translation.
 
Cite as: Haroon, H. (2024). Dealing with language variation in a source text: Malay Sketches and its Malay translation. Journal of Nusantara Studies, 9(2), 537-556. http://dx.doi.org/10.24200/jonus.vol9iss2pp537-556
SECURITISING HEALTH CRISES ON REGIONAL COOPERATION: HINDERING OR FACILITATING COOPERATION?
Authors: Mohd Azmi Nadirah
Published: July 2024

The securitisation theory (ST) often gives rise to the debate on the positive and negative dimensions of security. ST is frequently quoted in this debate to explore what happens when threats are labelled as a security issue. The positive and negative points in the debate on ST are closely related to migration, environment, and health. However, like other international relations (IR) theories, the ST debate often fails to reflect the voices and experiences of different regional contexts. This article contributed to the securitisation debates by adding the perspectives and experiences of the Southeast Asia region by applying critical literature review analysis, using primary and secondary sources data collection. Although public health challenges are global phenomena, the way they are addressed may vary across geographical regions. The article reviews the consequences of securitising on contagious diseases in Southeast Asia as the region is often associated with distinctive political cultures that shape the governing norms. Securitisation has clearly made a positive impact on the health security cooperation in the region. Instead of encouraging state-centric thinking, the securitisation of health crises has prompted ASEAN countries to be more region-centric, ultimately challenging the regional norms that have historically obstructed cooperation across the nations.
 
Keywords: ASEAN, health security, regional cooperation, securitisation theory, Southeast Asia.
 
Cite as: Mohd Azmi, N. (2024). Securitising health crises on regional cooperation: Hindering or facilitating cooperation. Journal of Nusantara Studies, 9(2), 557-576. http://dx.doi.org/10.24200/jonus.vol9iss2pp557-576
Temporal implementation of a regional referral pathway in transthyretin cardiac amyloidosis: Emilia-Romagna experience
Authors: Longhi Simone , Biagini Elena , Guaraldi Pietro , Carigi Samuela , Dossi Marco Currò , Bartolotti Michela , Gardini Elisa , Merli Elisa , Marzo Francesca , Luisi Giovanni Andrea , Postiglione Emanuela , Serenelli Matteo , Tugnoli Valeria , De Gennaro Riccardo , Caponetti Angelo Giuseppe , Gagliardi Christian , Saturi Giulia , Ponziani Alberto , Perugini Enrica , Rinaldi Rita , Barbieri Andrea , Bonatti Silvia , Ariatti Alessandra , Leuzzi Chiara , Codeluppi Luca , Serra Walter , Allegri Isabella , Lanati Gianluca , Terracciano Chiara , Cortelli Pietro , Galiè Nazzareno , Boriani Giuseppe
Published: July 2024

Aims

Transthyretin cardiac amyloidosis (ATTR-CA) is a rare and progressive cardiomyopathy caused by amyloid fibril deposition in myocardial tissue. Diagnostic challenges have historically hampered timely detection. Recent advances in noninvasive diagnostic techniques have facilitated ATTR-CA diagnosis. We aimed to examine the development of a regional network for the diagnosis and management of ATTR-CA and describe a cohort of patients with ATTR-CA, investigate diagnostic pathways and assess clinical outcomes according to diagnosis periods.

Methods

We performed a survey study analyzing answers from 11 cardiology centers and we conducted a retrospective study including patients with ATTR-CA attending a referral center between 1 January 2012 and 31 December 2022, and categorized by the period of diagnosis (2012–2016 and 2017–2022).

Results

Over the years, a growing number of patients reached a diagnosis and were treated in the surveyed nonreferral centers of the region. The retrospective study showed a more significant diagnostic delay in the earlier period rather than the later one [13.4 (5–30.2) vs. 10.6 (5.0–17.9) months, P = 0.04]. Patients diagnosed after 2017 showed a greater survival rate than those diagnosed earlier (P = 0.02). In the multivariate analysis, the year of diagnosis from 2017 remained independently associated with mortality [hazard ratio (HR) 0.46, 95% confidence interval (CI) 0.28–0.79; P = 0.005].

Conclusion

This study emphasized the shift toward noninvasive diagnostic criteria. It revealed a positive impact on patient survival and disease management with the use of disease-modifying therapies and diagnostic developments in more recent years. The findings underscore the importance of disease awareness and networking to reduce diagnostic delays and enhance patient journeys for ATTR-CA.
The influence of sex on heart failure mortality
Authors: Colombo Davide , Mercurio Valentina , Klersy Catherine , Temporelli Pierluigi , Rossi Andrea , Carluccio Erberto , La Rovere Maria Teresa , Dini Frank Lloyd L , Nappi Rossella , Acquaro Mauro , Greco Alessandra , Turco Annalisa , Schirinzi Sandra , Scelsi Laura , Ghio Stefano
Published: July 2024

Aims

Little research has investigated how sex may affect the prognosis of patients with chronic heart failure (HF). The present study was aimed at exploring sex-specific differences in prognosis in a cohort of patients with chronic HF, categorized according to severity of left ventricular dysfunction (HFrEF, HFmrEF and HFpEF), right ventricular (RV) dysfunction and ischemic (IHD) or nonischemic (no-IHD) etiology.

Methods

This retrospective analysis included 1640 HF patients of whom 24% were females, 759 patients had IHD, 1110 patients had HFrEF, 147 patients had HFmrEF and 383 patients had HFpEF. The median follow-up period was 63 months (25th–75th 27–93).

Results

In the no-IHD group, no statistically significant sex differences emerged regarding survival, regardless of age and severity of cardiac dysfunction. In contrast, in the IHD group, females had a significantly lower event rate than males in the age group between 65 and 79 years [hazard ratio (HR) 0.39; 95% confidence interval (CI): 0.86–0.18; P < 0.01]; in addition, a lower event rate was observed in females compared with males among patients with HFrEF (HR 0.47; 95% CI: 0.88–0.25; P < 0.01), among patients without RV dysfunction (HR 0.58; 95% CI: 1.02–0.33; P = 0.048) and among patients without diabetes (HR 0.44; 95% CI: 0.84–0.23; P < 0.01).

Conclusion

In nonischemic patients there was no difference between males and females in terms of survival whereas in patients with ischemic etiology survival was better in females among elderly patients, in HFrEF patients, in the absence of RV dysfunction and in the absence of diabetes.
Mineralization of equine proximal sesamoid bones precedes articular cartilage and fibrocartilaginous enthesis maturation in early postgestational development
Authors: Okudaira Mana , Cresswell Erin N. , Wollman Caroline W. , McDonough Sean P. , Engiles Julie B. , Reesink Heidi L.
Published: July 2024

OBJECTIVE

To describe the development and maturation of equine proximal sesamoid bones (PSBs) in fetuses and young horses using radiography, microcomputed (micro)-CT, and histology.

METHODS

A descriptive study. Forelimb PSBs from 12 equids ranging in age from 105 days of gestation to 540 days postgestation were evaluated. Radiography was used for preliminary assessment of metacarpophalangeal joint and PSB mineralization, and micro-CT imaging was performed to assess mineralized PSBs. Tissue volume, bone volume fraction, height, width, depth, trabecular thickness, and anisotropy were quantified from midplanar micro-CT sections in 3 dimensions. Midsagittal PSB histologic sections stained with H&E and Safranin O/Fast Green were used to determine the ratio of ossification center to cartilage template size and to describe the formation and development of the cartilage template, ossification center, spherical growth plate, articular cartilage, and entheses.

RESULTS

Mineralization of equine PSBs is associated with cartilage canals and a spherical growth plate that undergoes endochondral ossification during the late gestation to early postgestational period. The apical, flexor, basilar, and articular ossification fronts demonstrate morphologic variability. Structural organization of the articular cartilage and entheses occurs concurrently with the development of an underlying plate of compact bone. At 540 days postgestation, the fibrocartilaginous entheses of the flexor cortex of the PSB had yet to mature.

CONCLUSIONS

Equine PSBs mineralize predominantly by endochondral ossification during the late gestation to early postgestational period. Mineralization precedes maturation of the articular cartilage and fibrocartilaginous entheses.

CLINICAL RELEVANCE

The postgestational maturation of the PSB and its surrounding tissues may predispose young horses to developing lesions at these sites, such as apical avulsion fractures, warranting further investigation.
Identify The Relationship Between Scientific Writing Skills and Cognitive Skills During Laboratory Activities
Authors: Rahayu* Dita Puji , Meiliyanti Meiliyanti , Rabbani Annas
Published: July 2024

The lack of understanding about how scientific writing skills influence students' cognitive skills during laboratory activities. This study aimed to assess scientific writing skills and cognitive skills and explore their relationship among 49 first-semester science teacher candidates enrolled in a practical course on measurement tools and methods from February to June 2023. Cognitive skills were evaluated using reported response scores. Descriptive analysis revealed a spectrum of scientific writing skills, ranging from excellent to poor, among the participants, alongside generally low cognitive abilities. However, upon conducting correlation tests, it was found that there was no significant relationship between the ability to write reports and the response values (Sig = 0.117 0.05, rcount = 0.227 rtable = 0.281). The research findings suggest that scientific writing skills exhibit variance across different practical subjects, and notably, the ability to write reports does not appear to correlate with response scores. These insights shed light on the complex interplay between scientific writing proficiency and cognitive abilities during laboratory activities, urging further exploration into pedagogical strategies to enhance both skill sets in science education
Dynamic Evaluation of the Merdeka Curriculum: Unveiling the Effectiveness of Science Lesson Planning, Implementation and the Response of Junior High School Students
Authors: Henukh Anderias , Riandi Riandi , Setiawan* Agus , Rochintaniawati Diana , Irvani Asep Irvan , Suba Joey M
Published: July 2024

Merdeka curriculum is an education initiative in Indonesia that gives educators the flexibility to create learning that is more in-depth and suited to the needs of learners. This curriculum focuses on strengthening character and developing essential competencies, allowing students to go deeper into concepts and develop skills that are relevant to the challenges of the times. However, there are many obstacles in its implementation, especially in science learning, so it needs to be analyzed more deeply. The purpose of the research is to describe the planning, implementation, assessment, and students' responses to the implementation of the Merdeka curriculum in junior high school science subjects. The method used in this research is descriptive-quantitative. The subjects of this study were junior high school science teachers and students in grade VII in one of the private schools in the city of Bandung. The instruments used in this study were observation sheets and questionnaires. Based on the data analysis above, it can be concluded that the average score of science learning planning in the independent curriculum is 3.15, so it is in the good enough category. The average score of the science learning assessment obtained is 2.5, so it can be said that teachers still do not carry out learning assessments well. The average for all aspects of learner response has a good category, namely 73.62%. Thus, it is suggested that the teacher prepare everything related to learning activities to the maximum so that maximum results can be obtained
Textual Patterns and Virality in X: An Analysis of Engagement in Telenovela Posts
Authors: Ferreira William , Lima Jefferson
Published: July 2024

X, previously known as Twitter, boasts 556 million active users and is widely used by businesses to engage with their audiences. In our study, we focused on TV Globo's telenovela "Terra e Paixão" broadcast in 2023, to analyze the impact of textual patterns on post virality using natural language processing techniques. Techniques like sentiment analysis, Part-Of-Speech Tagging, reinforcement scoring, TF-IDF, semantic similarity, and cosine similarity were utilized to identify attributes that contribute to a post's success, aiming to enhance marketing strategies. We employed language models like BERT, RoBERTa, and e5 in our analysis. Our findings indicate that while various metrics affect post engagement, the challenge remains complex. Textual characteristics, although essential, do not fully explain a publication's popularity, underscoring the need for a multifaceted approach to understanding social media dynamics.
Pengaruh Hexagon Fraud terhadap Fraudulent Financial Statement pada Perusahaan BUMN yang Terdaftar di Bursa Efek Indonesia Periode 2017-2021
Authors: Sarmiah  , Raharjo Teguh Budi , Astutie Yanti Puji
Published: July 2024

Tujuan penelitian ini yaitu menguji pegaruh dari hexagon fraud terhadap fraudulent financial statement yang diproksikan enam komponen diantaranya tekanan, opportunity, rasionalization, capability, arrogance, serta kolusi. Terpilihnya perusahaan BUMN yang terdftar di BEI untuk periode 2017-2021 sebagai populasi penelitian hasilnya diperoleh sebanyak 13 sampel perusahaan dengan jumlah 65 unit analisis diambil berdasarkan purposive sampling dan dibantu alat analisis SPSS 22. Hasil penelitian membuktikan dimana kompone opportunity melalui nature of industry dan tekanan melalui external pressure berpengaruh pada fraudulent financial statement. Sebaliknya, komponen tekanan diukur melalui financial stability dan financial target; kemudian rasuonalization melalui change in auditor; capability melalui pergantian direksi; arrogance melalui number of CEO picture; dan kolusi melalui political connection tidak berpengaruh terhdap fraudulent financial statement.
Analisis Perbandingan Kinerja Karyawan Nissan Datsun Tegal Sebelum dan Sesudah Pelatihan
Authors: Hidayati Norma Nurul , Herwinarni Yuniarti
Published: July 2024

Penelitian ini bertujuan untuk meneliti menganalisis perbandingan kinerja karyawan se­belum dan sesudah pelatihan. Variabel yang digunakan dalam penelitian yaitu sebelum pe­la­tihan dan sesudah pelatihan sebagai variabel independen, dan kinerja sebagai variabel de­pen­den. Hipotesis dalam penelitian ini adalah H0: tidak terdapat perbedaan kinerja karyawan se­belum dan sesudah pelatihan dan Ha: terdapat perbedaan kinerja karyawan sebelum dan se­su­dah pelatihan. Penelitian ini menggunkan penelitian kuantitatif. Sumber data dalam pe­ne­li­ti­an ini yaitu data primer dimana metode pengumpulan data menggunakan metode kue­sio­ner yang disebar kepada seluruh karyawan Nissan Datsun Tegal. Jumlah sampel yang digu­na­kan berjumlah 30 responden.. Hasil penelitian ini menunjukkan bah­­wa ada pengaruh pe­ning­ka­tan kinerja sebelum dan sesudah pelatihan dilakukan. Hal ini me­n­jelaskan bahwa kinerja kar­yawan tidak hanya didukung oleh keinginan untuk bekerja, na­mun penunjang terbesar un­tuk pencapaian kinerja yang maksimal adalah pada pemberian pe­latihan oleh perusahaan.
Error Correction Model (ECM) For Macroeconomic Factors And LQ45 Stock Price Index
Authors: Yohanes Andri Putranto B  , Bernadette Robiani  , Mukhlis  , Siti Rohima
Published: July 2024

This research aims to test the causal effects of the inflation rate empirically, the Rupiah exchange rate against the United States Dollar, and world crude oil prices on the LQ45 stock price index. In its testing, this research uses the Error Correction Model (ECM) and uses data every month from 2000 to 2022. The research results show that the inflation rate, exchange rate and world gold prices significantly affect the LQ45 stock price index. Furthermore, the inflation rate and exchange rate have a negative influence on the LQ45 index. Not optimal company growth due to high inflation and exchange rates will affect public market share demand, thereby reducing share prices. Then, world crude oil prices positively influenced the LQ45 index. These results support previous research findings that changes in world crude oil prices positively affect stock market prices in developing countries.
The Seafood Restaurant Industry's Big Success?
Authors: Suryawan Ian Nurpatria
Published: July 2024

Innovative performing behaviour depends on the employee's personality; becoming innovative is the behaviour of an employee to create, recognise, and implement something new and bring profit to the company. Leaders' styles can be essential to increasing innovation in their work. This study was conducted at five seafood restaurants in North Jakarta with 60 respondents. Purposive sampling was the method of sampling. The questionnaires were distributed from early January 2024 to the end of January 2024. data were analysed using path analysis statistical tools. The target criteria for this research are employees from the staff level to middle-level managers from seafood restaurants who have worked for at least two years. This research shows that motivation and innovation performance do not significantly affect employee performance; the most influential factor in this study is the leader style.
Optimization of Process Parameters for Healthy and Nutritious Instant Ready-to-Cook Black Soybean Dal Premix
Authors: Rai Sweta ,   G.B.Pant University Of Agriculture And Technology
Published: July 2024

This study focuses on optimizing the process parameters for producing an antioxidant-rich, ready-to-cook black soybean dal, encompassing the stages of soaking, cooking, drying, and grinding. Black soybean seeds were soaked in aqueous solutions containing 0.5%, 1.0%, 1.5%, and 2.0% concentrations of NaCl and NaHCO3 separately, with soaking durations ranging from 2 to 12 hours at 30°C.
Nutritional and Sensory Properties of Cookies Produced from Flour Blends of African Walnut (Tetracarpidium Conophorum), Justicia Carnea and Wheat
Authors: Uchenna Enyi Chukwunwike ,   University Of Agriculture And Environmental Science Umuagwo
Published: July 2024

This study aims to evaluate the nutritional and sensory properties of cookies produced from flour blends of African walnut (Tetracarpidium conophorum), Justicia carnea and wheat.
A Comparison Study of Cryopreservation of Seminal Fluid between Flinders Technology Associates (FTA-card) and Swab for Multiplex Short Tandem Repeats (STR) Analysis
Authors: Namaa Dhuha Salim , Al-Janabi Thooalnoon Younes , Al-Sammarraie Halah Khalid Ibrahim , Mahdi Asia Abd-Alatief , AL-Rubai Haider K.
Published: July 2024

Background Whatman™ FTA (Flinders Technology Associates) is a form of card soaked in chemicals that denatures proteins while protecting DNA and ensuring the safe handling of dried body fluid spots (blood, semen, and saliva) and buccal cells. To this day, these cards are still infrequently used in forensic science. Therefore, reference samples including biological material may be collected on FTA cards for genetic analysis that have been widely used for DNA preservation and analysis, particularly in forensic sciences and genetic studies. The goal of the study was to evaluate the effects of cryopreservation on DNA quantitative and short tandem repeats (STR) profiling by comparing the yield and quality of DNA extracted before and after cryopreservation  using FTA card and swabs in the forensic analysis. The mean total DNA concentration and the purity of seminal fluid from FTA-cards and swabs before and after sperm cryopreservation were measured by using nano-drop spectrophotometer (93.688 ± 12.5) (90.94 ± 13.9) ng/ µl; ( 221.07 ± 20.97)( 135.47 ± 19.6) ng/ µl respectively. Also a highly significant difference (p<0.001) was detected when the results of concentration DNA on FTA card were compared with dilution using wash media before and after sperm cryopreservation. Whereas significant difference (p<0.05) was observed between DNA concentration on FTA card with and without dilution after sperm cryopreservation. STR loci were present in the majority of data, particularly in FTA-card and swab samples where results explained that 100% of STR profiles were present in all 15 loci, both before and after sperm cryopreservation. In contrast to the conventional method of storing and analyzing STR profiling, it can be concluded that seminal fluid samples taken by FTA card and swabs can be taken and stored for a time by cryopreservation, leads to maintaining DNA integration in the field of criminal research.
Prevalence of Extended-Spectrum ß-Lactamases (ESBLs) and AmpC ß-Lactamases in Clinical Isolates of Multiple Drug-Resistant Escherichia coli
Authors: Al-Hasani Halah M.H. , Al-Rubaye Dalal S. , Abdelhameed Alyaa
Published: July 2024

The current study aims to investigate the prevalence of extended-spectrum ß-lactamases (ESBLs) and AmpC β-lactamases in multiple-drug-resistant Escherichia coli (e.g., multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR)) collected from hospitalized patients in Baghdad. The results showed that the prevalence of ESBLs among E.coli isolates was high. From the total 113 E.coli isolates, 75 (66.37%) were ESBL-producing, while 38 (33.63%) were non-ESBL-producing. Out of 75 ESBL-positive isolates, 39 (52%) were obtained from females and 36 (48%) from males. Additionally, 43 (57.33%) isolates were collected from urine samples, and the highest production of ESBLs was obtained from the age group 41–60 years (29.33%). Moreover, out of 111 MDR E.coli, 64 (57.66%) exhibited a positive ESBL test, while 47 (42.34%) did not. Out of 24 XDR E.coli isolates, 11 (45.83%) demonstrated positive ESBLs, while 13 (54.17%) showed negative ESBLs. The antimicrobial susceptibility test results showed that positive ESBL E.coli isolates were more drug-resistant than negative ESBL isolates. The positive ESBLs of  E.coli exhibited a higher resistance rate to the β-lactam antibiotics and showed a co-resistance to non-β-lactam antibiotics. Phenotypic detection of AmpC β-lactamase by the screening of cefoxitin-resistant isolates revealed that 43 (38.05%) isolates were considered positive for AmpC β-lactamase production. However, the PCR technique gives different results. In conclusion, the prevalence of ESBL and AmpC β-lactamase producing E. coli is rapidly increasing among clinical isolates of MDR, XDR, and possibly PDR E.coli.
Determining the Genetic Markers of Schizophrenia using Molecular Diagnosis
Authors: Ismaeel Haneen M. , Badro Hayba , Khazaal Ali Q. , Ahmed Najwa Shihab
Published: July 2024

Schizophrenia poses a considerable disease burden, notwithstanding its relatively low incidence rate. The escalation in population size and mean age has led to a substantial rise in the incidence of illness linked to schizophrenia, particularly in countries with moderate levels of prosperity. Therefore, it is necessary to find a way to detect and recognize the illness as fast as possible to stop the consequences from occurring and stop symptoms from appearing before they even start. Within this study’s scope, fifteen distinct primers were selected randomly to determine whether or not they could recognize schizophrenia. To accomplish this, a Randomly Amplified Polymorphic DNA-polymerase chain reaction (RAPD-PCR) was conducted utilizing DNA samples obtained from individuals afflicted with the condition and those in good health. The outcomes of the gel electrophoresis and subsequent analysis revealed that solely three primers including C12, E02 and E03 exhibited monomorphic characteristics. However, it was observed that 80% of the primers, precisely eleven out of fifteen, exhibited polymorphism. The results indicated that among the 15 primers tested, the primer labeled as H01 failed to generate any detectable bands. Subsequent examination of the polymorphic primers revealed that the primer efficiency varied between 0 and 0.0755, while the discrimination power ranged from 0 to 20 percent. The study observed variations in the frequency of disease occurrence between patients and healthy individuals. H05 primer utilization yielded three distinct polymorphic bands exhibiting diverse lengths. The band exhibiting the greatest length measured 1190 bp, whereas the other two bands had 480 and 430 bp lengths respectively. The two polymorphic bands exhibited 100% prevalence in the patient population while being completely absent in the healthy control group. Based on the available data, it appears that utilizing this primer to identify schizophrenia is a valid and valuable claim. Overall, DNA-based diagnostics may overlook a number of difficulties as laboratories have the ability to extract DNA from various sources easily. In this scenario, molecular and genetic techniques may be crucial for diagnosing some diseases.
Investigation of Anti-inflammatory and Antioxidant Activities of Promising 1,4,5-Trisubstituted Pyrazoles Derivatives of Chalcone Ditosylates
Authors: Kumar Varun , Rao Chennu MM Prasada , Arora Pragi
Published: July 2024

Patients suffering from chronic pain and inflammatory disorders need novel COX-2 inhibitors to be developed with minimum toxicity to the kidneys, heart, and gastrointestinal tract and with excellent anti-inflammatory activity. The current study centers on an array of 1,4,5-trisubstituted pyrazoles produced via the reaction of ditosylates of chalcones with hydrochloride salt of phenylhydrazine. Chalcone was reacted with HTIB to produce a variety of derivatives of α, β chalcone ditosylates. Phenylhydrazine hydrochloride treatment of these chalcone ditosylates produced distinct 1,4,5-trisubstituted pyrazoles. The conversion process is mediated by 1,2-aryl migrations. IR, 1NMR, and elemental analysis were used to characterize the compounds after they had been purified by recrystallization. Using ascorbic acid as a reference, the DPPH (1,1-diphenyl-2-picrylhydrazyl) technique was used to assess the compounds' in vitro antioxidant activity. The paw edema technique caused by Carrageenan was utilized to assess the compounds' in vivo anti-inflammatory properties. The standard medication used was diclofenac sodium. A plethysmograph was used to measure the volume of the rats' paws. When compared to the standard, the compounds V5D5PH5 and V7D7PH7 showed modest antioxidant activity. When the synthetic pyrazoles were examined for their in vivo anti-inflammatory properties, substances V4D4PH4 and V7D7PH7 outperformed the reference. Here, we attempted to create new, safe, and effective drugs for the treatment of inflammatory disorders and pain by utilizing synthetic pyrazole moiety derivatives. Simple experimentation is used in the proposed study to improve pharmacological activity and yields. In the near future, chalcone ditosylate derivatives will be a powerful tool for selective modification.
Novel Development of Phytomedicine and its Innovative Formulation of Guava Leaf Extract Chocolates for Various Incredible Therapeutic Activities
Authors: Prabhakar T , Selvi D Baggiya , Sreedhar Chandanam , Jha Deepak Kumar
Published: July 2024

Incorporating guava leaf powder into chocolate is a creative way to boost its nutritional profile and potentially add a unique flavour. Guava leaf powder, being rich in soluble dietary fibre and vitamin C, can indeed enhance the health benefits of chocolate. Soluble dietary fibre can aid in digestion and promote gut health. Thus, the present study was to achieve an innovative formulation, i.e., guava leaf chocolates containing guava leaf extract and effective ingredients, which could be a way to entrap all the benefits of the guava leaf into an easy-to-consume formulation by increasing patient compliance and therapeutic outcomes. Response Surface Methodology (RSM) has been used here to optimise the formulation. RSM allows us to systematically vary the levels of these ingredients and analyse their impact on sensory attributes such as taste, texture, aroma, hardness, and overall acceptability. The use of various batches (F1 to F15) suggested a systematic approach to formulation adjustment, likely involving tweaking ingredient proportions and processing parameters to achieve the desired sensory attributes. The inclusion of physico-chemical analysis confirmed the stability of the formulation, ensuring product quality and consistency. And the results were felt within satisfactory a range, which indicates that the formulation was stable and suitable for its intended purpose, potentially for therapeutic applications. Furthermore, highlighting the eco-friendliness, ease of handling, and positive sensory attributes such as sweetness and flavour can contribute to the overall appeal of the product. By meeting these criteria, the formulation not only meets functional requirements but also aligns with consumer preferences and environmental considerations.
Numerical Solution of European Put Option for Black-Scholes Model Using Keller Box Method
Authors: Mardianto Lutfi , Putra Gusrian , Pratama Benediktus Ivan , Putri Endah R. M.
Published: July 2024

In this study, we propose to determine option pricing by using Black-Scholes model numerically. The Keller box method, a numerical method with a box-shaped implicit scheme, is chosen to solve the problem of pricing stock options, especiallyÂ European-put option. This option pricing involves several parameters such as stockÂ price volatility, risk-free interest rate and strike price. The numerical stability of theÂ method is checked using Von Neumann stability before the simulation is conducted. TheÂ influence of interest rates, volatility, and strike price on the option price state that theÂ higher the value of the interest rate parameter, the lower the option price value, whileÂ the greater the value of stock price volatility and strike price, the higher the option price.
Afectación de la crisis sanitaria (COVID 19) a la compra pública de alimentos de la agricultura familiar desde un enfoque de género: una comparación entre la región de Joinville (Brasil) y Nariño (Colombia)
Authors: Correa Kerber Gabriella Natallia , Zimermann Bail Suiany , Da Silva Dalonso Yoná , Goyes Moreno Isabel , Cecilia Torres Aura , Falcão Leal Brotero Duprat Mariana , Resende Yamamoto Gabriela
Published: July 2024

La pasada crisis sanitaria mundial evidenció el papel fundamental de la agricultura familiar y las políticas de compras pública para garantizar el derecho humano a la alimentación adecuada. En este análisis documental, se compararon las experiencias de compras públicas (2019 a 2022), en una región de Brasil y otra de Colombia, de la agricultura familiar, desde una perspectiva de género, con el objetivo de identificar desafíos y buenas prácticas. Entre los hallazgos, se destaca que, aunque ya existen políticas estructuradas para las compras públicas en Brasil, la realidad regional señaló desafíos en el período. Se señalaron los avances en Colombia, con la expedición de la Ley 2046 de 2020. En ambos países se evidenció el bajo rol de la mujer en la titulación de las propiedades rurales y en la toma de decisiones, aunque se evidencia su participación en la fuerza productiva rural familiar.
Tanslocación recíproca familiar. Doble mosaicismo autsómico y sexual
Authors: Delacruz Jairo A
Published: July 2024

En una familia el padre es portador de una translocación recíproca o balanceada entre 2 cromosomas; los 2 hijos de 5 y 6 años, respectivamente, presentan trisomía parcial de uno de estos cromosomas y monosomía parcial del otro. Un tercer hijo abortado a la semana 20 presentó en los fibroblastos la misma translocación del padre y un complemento sexual XY, pero en los linfocitos el grupo B fue normal, y curiosamente el complemento sexual era XX/YY. El cariotipo materno fue normal. Es la primera vez que se informa un doble mosaicismo autosómico y sexual.
Transmisión intrafamiliar de Shigella flexneri después de un brote en una guardaría de Cali
Authors: Koopman James S
Published: July 2024

En una guardería para niños de 3 a 7 años se estudió un brote de diarrea febril, debido a alimentos manipulados por una portadora convaleciente de Shigella flexneri. Se averiguó si había habido casos secundarios clínicos en las casas de los 56 niños enfermos a raíz de este brote y en las familias que compartían servicios sanitarios y cocinas, y solo se encontró transmisión importante en los miembros más inmediatos de la familia. Este hecho sugiere que la introducción de Shigella en la familia no es fácil y que sería posible reducir la transmisión intradomiciliaria de Shigella flexneri evitando su introducción con medidas tales como provisión adecuada de agua y control de alimentos.
Problemas de la terapéutica en Colombia
Authors: Gómez Héctor J
Published: July 2024

Artículo sin abstract disponible
Púrpura trombocitopénica idiopática en niños
Authors: Pereira Fabio D
Published: July 2024

La púrpura trombovitopénica idiopática de los niños (PTI) es una enfermedad benigna, autolimitada y con desaparición espontánea en la mayoría de los casos. Se presenta una revisión de la epidemiología, cuadro clínico, diagnóstico y tratamiento de la enfermedad, enfatizando la controversia que existe respecto al uso de esteroides, suprarrenales.
Hipermagnesemia neonatal como resultado del tratamiento de la Toxemia Materna
Authors: Rey Humberto , Miranda Reynaldo , Cifuentes Rodrigo
Published: July 2024

Se estudió el efecto en el recién nacido del Sulfato de Magnesio (MgSO4) administrado a madres toxémicas durante el trabajo de parto. Se estudiaron 35 madres toxémicas y 40 normales (grupo control) con los productos respectivos. Las madres toxémicas habían recibido MgSO4 a razón de 800-1000 mg por hora durante 24 horas. Se determinó la magnesemia, cuando había más de 5 cm de dilatación cervical, obteniendose un promedio de 2.89 +/- .54 mEq/L. El grupo control tuvo un Mg sérico de 1.39+/-0.18 mEq/L. En los recién nacidos los niveles de Mg en el cordón fueron de 2.72 +/- 1.25 mEq/L y 1.52 +/- 0.23 mEq/L para los hijos de toxémicas y controles respectivamente.
Apendicits aguda. Uso de Antibióticos
Authors: González Armando , Villareal Rubén , Ochoa Jorge Ernesto , Carvajal Reynaldo , Llanos Guillermo
Published: July 2024

Se analizareon las historias clínicas de 434 pacientes operados de apendicitis aguda en el Hospital Universitario del Valle en Cali, Colombia, en el período comprendido entre el 1o de enero de 1976 y el 31 de 1977. El propósito fundamental de este artículo es analizar la administración de antibióticos con apendicitis aguda no complicada y complicada.
Comparación de dos métodos para aprendizaje de los cuidados port-operatorios en casa
Authors: Pardo de Vélez Graciela
Published: July 2024

Se presentan resultados significativamente superiores del aprendizaje con unidades de autoinstrucción para los cuidados en casa de 39 pacientes o sus acompañantes respecto a otros 36 pacientes o sus acompañantes, quienes asistieron en grupo a las presentaciones con sonovisos y demostraron un aprendizaje superior a 80%. A la vez, se observa que l aprendido es realizado por la mayoría de ellos.
Mortalidad materna en el Hospital Universitario del Valle
Authors: Díaz Rodrigo
Published: July 2024

Los registros del Hospital Universitario del Valle (HUV) en Cali, durante 10 años, 1969-1978. muestran que hubo 79.9 nacimeintos y 358 muertes maternas, es decir una tasa de mortalidad materna de 4.47 por 1000 nacidos vivos. Este estudio establece la infección como la causa principal de muerte.
La familia, la salud y los servicios de salud en Colombia
Authors: Echeverri Óscar
Published: July 2024

Artículo sin abstract disponible
Renutrición en el niño: Cambios infecciosos, bioquímicos y hematológicos
Authors: Reyes Marco A. , McMurray David N. , Watson Ronald R.
Published: July 2024

En el Hospital Universitario del Valle (HUV), EN Cali, se admitieron 43 niños con desnutrición severa (kwashiorkor, 21; marasmo, 11; y mixta, 11) para estudio y tratamiento a base de una dieta hiperproteica e hipercalórica. La diarrea fue el problema infeccioso más común que se observó durante la recuperación nutricional, especialmente en los niños con kwashiorkor, pero además hubo infecciones de la piel y de los tractos respiratorio y urinario. Más de la mitad tenía parasitismo intestinal. Los datos bioquímicos y hematológicos en todos mostraron anemia moderada, colesterol bajo, en el suero disminución de las proteínas, la albúmina, el hierro y la transferrina, pero de manera más significante en el grupo con kwashiorkor. Los niños permanecieron hospitalizados entre 4 y 6 semanas, tiempo en el cual se procuró educar a las madres en hábitos alimenticios mejores. Cuando regresaron al hogar se observaron durante un año; 2 niños murieron por procesos infecciosos, 2 volvieron al grado III de desnutrición, pero aproximadamente 80% se conservaron bien o con grados leves o moderados de desnutrición. Los parámetros hematológicos y bioquímicos, al final del año estaban en límites normales.
Extractos del XIV Congreso de la Asociación Colombiana de Ciencias Biológicas
Authors: Barreto Pablo
Published: July 2024

I. Bioquimica y Fisiología.II. EcologíaIII. Genética y ReproducciónIV. Microbiología, Parasitología V. Morfologia y Taxonomia.
Las publicaciones científicas.
Authors: Barreto José Fernando , Barreto Pablo
Published: July 2024

El aporte de un científico a la ciencia, en general, y a su especialidad, en particular, depende sustancialmente de la publicación de sus conocimientos.La investigación se inicia y concluye en la literatura científica. Lo primero, porque el estudio de las contribuciones que otros hayan hecho en determinado campo permite, a quien inicia un proyecto, definir con mayor precisión el problema objeto de su cuidado. Y lo segundo, porque todo trabajo debe dar como fruto un aporte a la literatura científica especializada para que los esfuerzos y hallazgos del equipo investigador se puedan conocer, valorar y duplicar con el propósito de validarlos.
Recursos neuroquirúrgicos en el sur-occidente de Colombia
Authors: Zuñiga Arcesio
Published: July 2024

Se hizo un inventario de los recursos humanos y físicos existentes en el sur-occidente colombiano, para la práctica de la neurocirugía, desde Agosto 1 de 1977 a Julio 31 de 1978. En ese período se realizaron procedimientos quirúrgicos de los cuales 349 en el Hospital Universitario del Valle (HUV) en Cali, 151 en la Clínica del Instituto de Seguros Sociales (ISS) y el resto en clínicas particulares. Del total 222 fueron traumas craneanos; 133, laminectomías, aneurismas, 27; tumores, 28 y el resto por otros procedimientos. En el momento del estudio había 12 neurocirujanos, 4 residentes en entrenamiento y 4 hospitalarios en el ISS. De las 71 camas especializadas, 50 pertenecían al ISS y 21 al HUV; con una productividad de 3 y 16 egresos quirúrgicos por cama y por año, respectivamente. Se observó una relación más o menos constante de 4 procedimientos quirúrgicos por cada 100 consultas externas. Hay una franca subutilización de los recursos neuroquirúrgicos razón por la cual parece conveniente programar mejor la formación de especialistas.
Interacción diarrea-desnutrición
Authors: Levy Farín Alberto
Published: July 2024

La enfermedad diarreica aguda constituye una de las principales causas de morbi-mortalidad en los niños menores de 5 años de los países en desarrollo. La presente publicación tiene por objeto analizar los mecanismos de interacción entre diarrea y desnutrición y plantear soluciones al problema que estén al alcance de los países subdesarrollados, haciendo especial énfasis en el manejo dietético e hidratación oral del niño con diarrea.
Extractos de la Literatura Médica Mundial
Authors: Guillen Maria Alejandra
Published: July 2024

Terapia con Hidralazina oral para la hipertensión pulmonar primaria. La incidencia del cáncer de endometrio en relación con el uso de anticonceptivos orales.Hepatitis Viral: Avances y problemas. El manejo del asma severo agudo.La epidemiología de la enterocolitis necrotizante: un estudio de casos y controles.Hiperparatiroidismo primario.Farmacoterapia del Asma bronquial.Banco de sangre en el pequeño hospital.Los efectos del embarazo y los esteroides contraceptivos en la función de la vesícula.La enfermedad diverticular en el colon.Síndrome del prolapso de la válvula mitral: espectro y terapéutica.Giardiasis.La relación de la dieta con el colesterol de lipoproteína de alta densidad en hombres maratonistas, trotadores e inactivos de edad mediana.Las estrategias en el tratamiento de las infecciones sistémicas por hongos.Adelantos en el tratamiento de la obstrucción de los conductos biliares: colangiografia transhepatica percutanea y colangiopancreatografia retrograda por endoscopia.Complementos de vitaminas y minerales en el tratamiento de enfermedades del hígado.
Mosquitos comunes en Cali, Colombia.
Authors: Fajardo Paulina , Arias Amelia
Published: July 2024

Mediante un método sencillo de encuesta se logró averiguar cuales son las especies de mosquitos más comunes en la Ciudad de Cali. Casi 90% de los ejemplares capturados correspondian al género culex, dentro del cual C. nigripalpus y C. quinquefasciatus fueron las especies más comunes. Se confirmó la presencia en el área urbana de 2 representantes del género Anopheles. Se informa la reinvasion en el Valle del Cauca, a partir de 1978, de la especie Aedes aegypti.
La historia clínica orientada por problemas.
Authors: Gutierrez Javier
Published: July 2024

Se revisa la manera de elaborar una historia clínica orientada por problemas, y se enseña cómo hacerla mediante un ejemplo práctico. Entre sus ventajas sobresalen que mejora el cuidado del paciente, y crea en el médico mismo y en el estudiante de medicina una serie de actitudes de análisis, síntesis, sistematización, honestidad y empleo del método científico, más útiles para el ejercicio profesional, que los mejores conocimientos cambiantes transmitidos por los profesores.
Anemia Aplastica en niños
Authors: Sardi Alirio , Pereira Fabio
Published: July 2024

De 1977 a 1980 en el Hospital Universitario del Valle en Cali fue posible estudiar 9 casos de anemia aplástica que ocurrieron en niños de ambos sexos entre 5 y 12 años de edad. En este artículo se presentan los hallazgos clínicos, los datos de laboratorio, la evolución y las medidas terapéuticas que se tomaron en estos casos.