bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PENGARUH FAKTOR-FAKTOR MASUKAN SISTEM OPERASIONAL TERHADAP DINAMIKA PERKEMBANGAN PERUSAHAAN, KASUS PERUSAHAAN INDUSTRI MIKRO BUBUK KOPI
Authors: Suroyo
Published: March 2020

Penelitian ini bertujuan untuk menguji pengaruh faktor-faktor masukan sistem operasional terhadap dinamika perkembangan perusahaan (perkembangan nilai produksi) pada perusahaan industri mikro bubuk kopi di Kelurahan Bukit Apit Puhun, Kecamatan Guguk Panjang, Kota Bukittinggi. Populasi penelitian adalah seluruh pengusaha industri mikro bubuk kopi di Kelurahan Bukit Apit Puhun, Kecamatan Guguk Panjang, Kota Bukittinggi, yaitu sebanyak 75 pengusaha industri mikro bubuk kopi. Karena populasi penelitian tidak terlalu banyak, maka penelitian ini mengambil seluruh populasi penelitian sebagai sampel penelitian. Penelitian ini menghasilkan dua hasil penelitian. Pertama, perkembangan kemampuan memperkerjakan tenaga kerja (X1), perkembangan gaji tenaga kerja (X2), perkembangan penguasaan teknologi dan peralatan produksi (X3), perkembangan kemampuan mendesain produk (X4), perkembangan total asset (X5), perkembangan permintaan pasar (X6), perkembangan kemampuan menyediakan bahan baku (X7), perkembangan harga bahan baku (X8), dan perkembangan penguasaan informasi dan ilmu manajemen (X9) secara bersama- sama (uji F) sebesar 86% mempengaruhi dinamika perkembangan perusahaan (perkembangan nilai produksi) perusahaan industri mikro bubuk kopi di Kelurahan Bukit Apit Puhun, Kecamatan Guguk Panjang, Kota Bukittinggi. Sedangkan sisanya dinamika perkembangan perusahaan (perkembangan nilai produksi) perusahaan industri mikro bubuk kopi di Kelurahan Bukit Apit Puhun, Kecamatan Guguk Panjang, Kota Bukittinggi dipengaruhi sebesar 14% oleh faktorfaktor yang tidak diketahui dan tidak termasuk dalam model penelitian ini. Kedua, faktor perkembangan permintaan pasar (X6) dan perkembangan penguasaan informasi dan ilmu manajemen (X9) paling berpengaruh terhadap
STRATEGI PERGURUAN TINGGI DALAM MENINGKATKAN JIWA KEWIRAUSAHAAN PADA MAHASISWA STMIK MITRA KARYA BEKASI
Authors: Anita Novialumi
Published: March 2020

Penelitian ini mendeskripsikan hasil penelitian yang bertujuan untuk mengetahui strategi apa yang digunakan perguruan tinggi dalam meningkatkan jiwa kewirausahaan mahasiswa dan untuk mengetahui kendala apa saja yang dihadapi perguruan tinggi dalam peningkatan jiwa kewiraushaan. Dalam pengumpulan data, peneliti menggunakan metode wawancara, dan dokumentasi yang dimana metode tersebut dilakukan untuk memperoleh data secara jelas dan rinci. Hasil penelitian menjelaskan bahwa ada beberapa strategi yang digunakan oleh STIMIK Mitra Karya Bekasi dalam meningkatkan jiwa kewirausahaan mahasiswa. Strategi tersebut meliputi: kuliah kewirausaan, KKN-usaha, magang kewirausahaan, dan program kreatif mahasiswa. Dalam melaksanakan strategi tersebut pastinya di dalamnya terdapat beberapa kendala dalam prosesnya. Kendalakendala tersebut adalah jiwa kewirausahaan yang lemah, kurangnya tanggung jawab para mahasiswa dalam tugas yang diberikan, kurang pemantauan, dan yang paling utama adalah masalah dana.
ANALISIS PENGARUH GAJI DAN TUNJANGAN KESEJAHTERAAN TERHADAP PRODUKTIVITAS KERJA KARYAWAN OPERATION DEPARTMENT PT. EXPORT LEAF INDONESIA.
Authors: Setiyo Utomo
Published: March 2020

Tujuan penelitian adalah untuk mengetahui pengaruh antara gaji dan tunjangan kesejahteraan karyawan terhadap produktivitas kerja karyawan Operation Department PT. Export Leaf Indonesia, dan untuk mengetahui pengaruh yang paling dominan di antara gaji dan tunjangan kesejahteraan karyawan terhadap produktivitas kerja karyawan Operation Department PT. Export Leaf Indonesia. Populasi sebanyak 628 responden. Namun, karena tenaga kerja permanen hanya 28 orang akan diambilkan jumlah tenaga permanen semuanya sebagai sampel. Jadi besar sampel dalam penelitian ini sebanyak 28 responden. Metode kuisioner digunakan sebagai pengumpul data dan dianalisis dengen metode regresi linier berganda. Hasil penelitian menunjukkan bahwa: 1) Ada pengaruh yang signifikan secara parsial antara gaji dan tunjangan kesejahteraan terhadap produktivitas kerja diketahui dari t hitung gaji = 2,529 > t tabel = 2,048 (Sig. = 0,018 < a = 0,05) dan t hitung tunjangan = 2,705 > t tabel = 2,048 (Sig. 0,012 < a = 0,05). 2) Ada pengaruh secara serentak antara gaji dan tunjangan kesejahteraan terhadap peningkatan prestasi kerja karyawan diketahui dari F hitung = 14,292 > F tabel = 3,39. dan 3) Diketahui pengaruh paling dominan di antara gaji dan tunjangan kesejahteraan adalah pengaruh gaji terhadap produktivitas kerja berdasarkan koefisien regresi yang lebih besar yaitu sebesar 0,821 dibandingkan dengan koefisien regresi tunjangan kesejahteraan sebesar 0,759.
PENGARUH STRATEGI PEMASARAN TERHADAP PENINGKATAN PENJUALAN PADA PERUSAHAAN
Authors: Fajar Azzam Pasha Akhmad
Published: March 2020

Tujuan penelitian ini adalah untuk mendeskripsikan adanya pengaruh strategi pemasaran terhadap peningkatan penjualan pada perusahaan. Pendekatan yang digunakan dalam penelitian ini adalah dengan metode pengumpulan data. Metode ini dilakukan dengan dua cara yiatu dengan studi kepustakaan dan studi lapangan. Data diperoleh dalam penelitian ini dari wawancara terhadap 15 orang alumni STIE Tribuana yang telah menjadi wirausaha. Dengan menganalisis hasil survey ddengan berdasarkan kegiatan penelaahan dan kajian teori-teori yang ada pada literature yang telah dikumpulkan, responden menganggap penting penggunaan strategi pemasaran pada perusahaannya agar perusahaannya dapat berkembang dan berjalan dengan baik sejalan dengan teknologi pada saat ini
NEW MODEL OF THE VERTICAL CRUSTAL MOVEMENTS IN THE AREA OF POLAND
Authors: Kowalczyk Kamil
Published: March 2020

In 2003 the fourth levelling campaign has been finished in Poland. This campaign, together with the previous
one carried out in 1974–1982, gave a very good opportunity to determine the land uplift in the area of Poland. The paper describes
shortly the third and fourth campaigns, the computation of the relative land uplift, computation of land uplift referred to the mean
sea level and modeling the land uplift by the least-squares collocation method. Obtained results are compared with the computation
done by the Institute of Geodesy and Cartography in 1986.
The Frequency Drift and Fine Structures of Solar S-bursts in the High Frequency Band of LOFAR
Authors: Zhang PeiJin , Zucca Pietro , Wang ChuanBing , Bisi Mario M. , Da̧browski Bartosz , Fallows Richard A. , Krankowski Andrzej , Magdalenic Jasmina , Mann Gottfried , Morosan Diana E. , Vocks Christian
Published: March 2020

Solar S-bursts are short duration (<1 s at decameter wavelengths) radio bursts that have been observed during periods of moderate solar activity, where S stands for short. The frequency drift of S-bursts can reflect the coronal density variation and the motion state of the electron beams. In this work, we investigate the frequency drift and the fine structure of the S-bursts with the Low Frequency Array (LOFAR). We find that the average frequency drift rate of the S-bursts within 20–180 MHz could be described by df/dt = −0.0077f
1.59, combined with previous results in low frequency. With the high time and frequency resolution of LOFAR, we can resolve the fine structures of the observed solar S-bursts. A fine drift variation pattern was found in the structure of S-bursts (referred to as solar Sb-bursts in this paper) during the type-III storm on 2019 April 13, in the frequency band of 120–240 MHz. The Sb-bursts have a quasiperiodic segmented pattern, and the relative flux intensity tends to be large when the frequency drift rate is relatively large. This kind of structure exists in about 20% of the solar S-burst events within the observed frequency range. We propose that the fine structure is due to the density fluctuations of the background coronal density. We performed a simulation based on this theory that can reproduce the shape and relative flux intensity of the Sb-bursts. This work shows that the fine structure of solar radio bursts can be used to diagnose the coronal plasma.
Shock Drift Acceleration of Ions in an Interplanetary Shock Observed by MMS
Authors: Hanson E. L. M. , Agapitov O. V. , Vasko I. Y. , Mozer F. S. , Krasnoselskikh V. , Bale S. D. , Avanov L. , Khotyaintsev Y. , Giles B.
Published: March 2020

An interplanetary (IP) shock wave was recorded crossing the Magnetospheric Multiscale constellation on 2018 January 8. Plasma measurements upstream of the shock indicate efficient proton acceleration in the IP shock ramp: 2–7 keV protons are observed upstream for about three minutes (∼8000 km) ahead of the IP shock ramp, outrunning the upstream waves. The differential energy flux of 2–7 keV protons decays slowly with distance from the ramp toward the upstream region (dropping by about half within 8 Earth radii from the ramp) and is lessened by a factor of about four in the downstream compared to the ramp (within a distance comparable to the gyroradius of ∼keV protons). Comparison with test-particle simulations has confirmed that the mechanism accelerating the solar wind protons and injecting them upstream is classical Shock Drift Acceleration (SDA). This example of observed proton acceleration by a low-Mach, quasi-perpendicular shock may be applicable to astrophysical contexts, such as supernova remnants or the acceleration of cosmic rays.
Micro-elimination of HCV as a possible therapeutic strategy: our experience and a review of literature
Authors: Bojovic Ksenija , Simonovic-Babic Jasmina , Mijailovic Zeljko , Milosevic Ivana , Jovanovic Maja , Ruzic Maja , Cvejic Pasic Tatjana , Svorcan Petar , Petrovic Milena , Jordovic Jelena
Published: March 2020

Background: Serbia has an intermediate estimated prevalence of chronic hepatitis C (CHC) infection, approximately 1.13%, with hepatitis C remaining one of the leading causes of liver-related morbidity and mortality in Serbia with impaired quality of life and overwhelming cost of treating its complications As the availability of new treatment options and resources for screening remains limited, micro-elimination of CHC becomes a top priority.

Methods: Review of the available published data related to the clinical and epidemiological situation of the hepatitis C infection in Serbia, including the unpublished data from the databases of four major reference centres in Serbia (Clinical Center Serbia, Clinical Center Niš, Clinical Center Vojvodina and Clinical Center Kragujevac).

Results: Currently in Serbia, micro-elimination appears to be realistic in the patients with haemophilia, who represent a small, well-defined subpopulation, under constant monitoring by the healthcare system. Other feasible targets for micro-elimination of CHC infection in Serbia are patients on hemodialysis, prisoners and people who inject drugs.

Conclusions: Micro-elimination is feasible in Serbia, especially in the subpopulation of patients with haemophilia. This may represent an initial step towards achieving the WHO objective to eliminate hepatitis C infection by 2030.
Similarity in Case Fatality Rates (CFR) of COVID-19/SARS-COV-2 in Italy and China
Authors: Porcheddu Rossella , Serra Caterina , Kelvin David , Kelvin Nikki , Rubino Salvatore
Published: March 2020

As of 28 February 2020, Italy had 888 cases of SARS-CoV-2 infections, with most cases in Northern Italy in the Lombardia and Veneto regions. Travel-related cases were the main source of COVID-19 cases during the early stages of the current epidemic in Italy. The month of February, however, has been dominated by two large clusters of outbreaks in Northern Italy, south of Milan, with mainly local transmission the source of infections. Contact tracing has failed to identify patient zero in one of the outbreaks. As of 28 February 2020, twenty-one cases of COVID-19 have died. Comparison between case fatality rates in China and Italy are identical at 2.3. Additionally, deaths are similar in both countries with fatalities in mostly the elderly with known comorbidities. It will be important to develop point-of-care devices to aid clinicians in stratifying elderly patients as early as possible to determine the potential level of care they will require to improve their chances of survival from COVID-19 disease.
Les inégalités d’accès à l’enseignement supérieur français
Authors: Herbaut Estelle
Published: March 2020

Résumé Avec l’allongement de la scolarité, les inégalités sociales d’accès à l’enseignement supérieur sont devenues une préoccupation majeure de la recherche sur la stratification sociale. Cet article vise à décrire empiriquement le développement des inégalités tout au long de l’enseignement secondaire pour expliquer les inégalités d’accès à l’enseignement supérieur français. En se fondant sur le panel d’élèves du second degré 1995, il estime que les inégalités d’accès au supérieur résultent à 81 % d’inégalités dans l’obtention du baccalauréat. Confirmant l’aspect cumulatif de la scolarité, l’accumulation de résultats scolaires négatifs pendant le secondaire contribue largement à la sous-représentation des élèves défavorisés parmi les bacheliers. Les données montrent aussi que les trajectoires des élèves avec des difficultés scolaires initiales similaires divergent largement selon le niveau d’instruction des parents, confirmant l’hypothèse de l’avantage compensatoire. À l’inverse, un effet de renforcement, menant à des trajectoires divergentes entre bons élèves, suivant l’origine sociale, est aussi mis en évidence pour l’accès aux filières prestigieuses du supérieur et vient compléter l’hypothèse de l’avantage compensatoire. Ces résultats soulignent la nécessité de considérer les interactions entre performance scolaire et milieu social pour appréhender le développement des inégalités tout au long de la scolarité.
La haute fonction publique entre organisations, professions et patrons
Authors: Gally Natacha
Published: March 2020

Résumé Cet article réactualise les observations empiriques formulées il y a plus de cinquante ans sur l’organisation corporatiste de la haute fonction publique en France en les réinsérant dans une analyse comparée des marchés du travail administratifs. En nous appuyant sur les travaux de Neil Fligstein, nous proposons de considérer les marchés du travail administratifs comme des constructions institutionnelles, produits des interactions entre trois types d’acteurs : des groupes professionnels, des organisations administratives et des dirigeants politiques. Nous construisons ensuite trois idéaux-types de marchés du travail administratifs pouvant servir de guide à la comparaison des trajectoires d’institutionnalisation de la haute fonction publique dans différents pays.
Entre desserrement et resserrement du verrou de l’État
Authors: Le Lidec Patrick
Published: March 2020

Résumé Cet article explore les transformations du modèle d’administration territoriale français et les processus de migration de l’autorité depuis le milieu des années 1970 à partir des mobilisations de deux grandes catégories d’acteurs : les élus locaux, leurs associations et leurs relais institutionnels au Sénat, d’une part ; les hauts fonctionnaires des administrations centrales, et particulièrement ceux du ministère du Budget, d’autre part. Il cherche à identifier les contextes et mécanismes qui ont permis la conversion d’asymétries ponctuelles de pouvoir en asymétries plus durables, qui ont modifié les trajectoires de réforme. Il met en évidence une dynamique de desserrement du verrou de l’État, qui court depuis le milieu des années 1970 jusqu’au milieu des années 1990, et connaît son apogée avec le vote des lois de décentralisation. Il montre a contrario pourquoi l’adoption de l’euro s’est traduite par un recul très net de l’autonomie budgétaire et fiscale des collectivités et par l’adoption de politiques de fusions de collectivités, et comment la crise des dettes souveraines a amplifié ce resserrement du verrou de l’État.
Conceptualizing LEAD
Authors: Salinitri Geri , Pizzo Dana L. , Furlong Kathleen
Published: March 2020

At a critical point in education, teachers are the agents that can positively affect the outcomes of all learners. Preparing teachers to understand youth and the challenges they face through globalization, economic uncertainties, and social inequities must begin in Teacher Education programs. L.E.A.D. (Leadership Experience for Academic Directions) is a service-learning program designed from a need to reach marginalized and vulnerable youth, to aid in closing the achievement gap, and advocating for social justice and inclusion. This chapter highlights the conceptualization of L.E.A.D. based on research, theory, and practice.
Service-Learning
Authors: Palazzolo Alyssa N.
Published: March 2020

This chapter explores the theoretical underpinnings of service-learning. A brief overview of past and current definitions of service-learning, and its defining elements and benefits to all stakeholders will be explored. This chapter will also frame Leadership Experience for Academic Direction (L.E.A.D.) in the service-learning context through a discussion of the process facilitated through the program (preparation, action, reflection, demonstration) based on literature. Within the L.E.A.D. program, teacher candidates conduct a needs assessment, prepare a project proposal, and compile all information from planning and resources into a final project that showcases their learning.
LEAD Legacy Projects
Authors: Palazzolo Alyssa N. , Pizzo Dana L.
Published: March 2020

The L.E.A.D. Program implements two Legacy Projects, annually: Power of Potential Youth Conference and Challenge Cup. Both events are planned, organized, and facilitated by teacher candidates with the goal of engaging in-risk youth in various capacities. Taking place in the fall, the Power of Potential Youth Conference allows local high school students to explore some of their options for life after secondary school through a series of presentations and workshops focusing on Financial Literacy, Healthy Active Living, and Career Exploration. Taking place each spring, Challenge Cup is an outdoor event that fosters leadership, character development, and self-confidence in local secondary students. Students participate in a series of physical activities throughout the day which focus on building team-work, community, and leadership skills. This chapter explores how both L.E.A.D. Legacy Project events support secondary students outside of the classroom. The planning and organization of both events will be explained.
Structure of LEAD in the Secondary Panel
Authors: Nahaiciuc Ruxandra Bianca
Published: March 2020

This chapter provides readers with an applied example of the L.E.A.D. Program for Teacher Candidates within the secondary panel. This intrinsic case study explores a compensatory school's student success solution through an increase of Student Success Literate (SSL) Student Teachers. Their presence and conscious efforts contribute to the overall implementation of the school's student success strategies, adapted from Adlai Stevenson High School's intervention model. The five main themes that emerged were: i) the collective is a benefit; ii) visibility and accountability; iii) shift in teaching approaches; iv) increased individual support; and, v) holistic education. Research findings indicate how the L.E.A.D. program shapes teachers into mindful educators equipped with foundational knowledge that bolsters student success and provides an accurate depiction of the working structure of the program in the secondary panel.
LEAD Testimonials
Authors: Palazzolo Alyssa N.
Published: March 2020

Through service-learning courses, the University of Windsor's Faculty of Education seeks to provide meaningful learning opportunities in different areas of education for teacher candidates. This chapter includes a summary of a Master's thesis research study that, in part, explored the impact of the experiences secondary teacher candidates had in the L.E.A.D. Program, and how their experience impacted their efficacy with diverse student populations. The important themes that emerged from their reported experiences were practical experience, empathy and understanding, social learning, and life-long learning. This chapter also includes a compilation of testimonials from both elementary and secondary teacher candidates that were collected at various points after their graduation.
Transformational Learning Theory and Service-Learning Projects
Authors: Kornacki Gillian
Published: March 2020

This chapter investigates the University of Windsor's service-learning program Leadership Experience for Academic Direction's (L.E.A.D.) impact on teacher candidates' perceptions of teaching in-risk students. The L.E.A.D. program focuses on introducing teacher candidates to the Ministry of Ontario's Student Success initiatives and reflective teaching practices, and places teacher candidates with Student Success Teachers, allowing teacher candidates to learn from in-risk youth. This study adopted a qualitative approach using Interpretative Phenomenological Analysis (IPA) to examine the lived experience of graduates of the L.E.A.D. program. Five graduates of the L.E.A.D. program who are currently practicing secondary teachers in southwestern Ontario were interviewed in one focus group and one individual interview. The responses indicated themes of the importance of relationship building with students, the value of school support systems, the positive impact of L.E.A.D. coursework, and altered efficacy and perceptions of teaching in-risk youth.
Deep Learning in Cybersecurity
Authors: Imamverdiyev Yadigar N. , Abdullayeva Fargana J.
Published: March 2020

In this article, a review and summarization of the emerging scientific approaches of deep learning (DL) on cybersecurity are provided, a structured and comprehensive overview of the various cyberattack detection methods is conducted, existing cyberattack detection methods based on DL is categorized. Methods covering attacks to deep learning based on generative adversarial networks (GAN) are investigated. The datasets used for the evaluation of the efficiency proposed by researchers for cyberattack detection methods are discussed. The statistical analysis of papers published on cybersecurity with the application of DL over the years is conducted. Existing commercial cybersecurity solutions developed on deep learning are described.
A Literature Review on Automation Testing Using Selenium+Sikuli
Authors: Lathwal Ashish
Published: March 2020

Automation testing is a methodology that uses an application to implement the entire life cycle of the software in less time and provides efficiency and effectiveness to the testing software. In automation testing, the tester writes scripts and uses any suitable application software to test the software application. Automation is basically an automated process that is comprised of lots of manual activities. In other words, automation testing uses automation tools like Selenium, Sikuli, Appium, etc., to write test script and execute test cases, with no or minimal manual involvement required while executing an automated test suite. Usually, automation testers write test scripts and test cases using any of the automation tool and then groups test several cases. Here, we will discuss a neat case study explaining the automation testing using a hybrid test script.
Rule Base Simplification and Constrained Learning for Interpretability in TSK Neuro-Fuzzy Modelling
Authors: Rajab Sharifa
Published: March 2020

Neuro-fuzzy systems based on a fuzzy model proposed by Takagi, Sugeno and Kang known as the TSK fuzzy model provide a powerful method for modelling uncertain and highly complex non-linear systems. The initial fuzzy rule base in TSK neuro-fuzzy systems is usually obtained using data driven approaches. This process induces redundancy into the system by adding redundant fuzzy rules and fuzzy sets. This increases complexity which adversely affects generalization capability and transparency of the fuzzy model being designed. In this article, the authors explore the potential of TSK fuzzy modelling in developing comparatively interpretable neuro-fuzzy systems with better generalization capability in terms of higher approximation accuracy. The approach is based on three phases, the first phase deals with automatic data driven rule base induction followed by rule base simplification phase. Rule base simplification uses similarity analysis to remove similar fuzzy sets and resulting redundant fuzzy rules from the rule base, thereby simplifying the neuro-fuzzy model. During the third phase, the parameters of membership functions are fine-tuned using a constrained hybrid learning technique. The learning process is constrained which prevents unchecked updates to the parameters so that a highly complex rule base does not emerge at the end of model optimization phase. An empirical investigation of this methodology is done by application of this approach to two well-known non-linear benchmark forecasting problems and a real-world stock price forecasting problem. The results indicate that rule base simplification using a similarity analysis effectively removes redundancy from the system which improves interpretability. The removal of redundancy also increased the generalization capability of the system measured in terms of increased forecasting accuracy. For all the three forecasting problems the proposed neuro-fuzzy system demonstrated better accuracy-interpretability tradeoff as compared to two well-known TSK neuro-fuzzy models for function approximation.
DICE
Authors: Djaouti Damien
Published: March 2020

This article deals with serious game design methods. More specifically, it focuses on the following question: is there any universal series of steps to design a serious game? Or is the availability of several different design methods unavoidable? To try to answer this question, we will study a corpus of ten design methods suited to Serious Games. Most of these theoretical tools are coming from or aimed to industry professionals. This literary review will allow us to perform a comparative analysis over the various steps used by these methods, in order to build a generic model for the design process of Serious Games: the Design / Imagine / Create / Evaluate (D.I.C.E.) model.
Marketing Analytics for Customer Engagement
Authors: Nagaraj Samala
Published: March 2020

Customer engagement is the buzz word in marketing discipline today. Engaging customers has never been as effective before the emergence of marketing analytics and its application. Marketing analytics coupled with social media and brand communities has given rise to improved innovative ways to engage customers across various service industries. The integration of marketing analytics with artificial intelligence (AI) has enhanced marketers understanding of customer engagement. The present article is a viewpoint on the various applications of marketing analytics for customer engagement. The present article focuses on the evolution of marketing analytics, its various models and application in various forms of customer engagement. The article highlights the future applications of analytics and concludes with the importance of marketing analytics for marketers in increasing customer engagement.
Ecotoxicological Modeling of Organic Chemicals for Their Acute Toxicity in Algae Using Classification and Toxicophore-Based Approaches
Authors: Khan Kabiruddin , Ojha Probir Kumar
Published: March 2020

To study the relationship between toxicity of organic chemicals (OCs) with their structural and physicochemical features, the authors have developed a linear discriminant analysis (LDA) model for the classification of organic chemicals based on their acute observed toxicity in algae. This is done by employing a sufficiently large dataset of 352 chemicals following the strict Organization for Economic Cooperation and Development (OECD) guidelines for the quantitative structure-activity relationship (QSAR) validation. Additionally, 3D toxicophore models were generated to explore for the presence of common features contributing to the toxicity making chemicals a major concern for the future. Both of the models were rigorously validated following stringent validation criteria such as Wilks' λ statistic, canonical index (Rc), squared Mahalanobis distance, and chi-squared. Finally, a confusion matrix was employed to check for the quality of classification/prediction obtained for the LDA and pharmacophore models both in the training and the test sets.
A Bidirectional Reasoning Based on Fuzzy Interpolation
Authors: Jin Shangzhu
Published: March 2020

In order to deal with both the “curse of dimensionality” and the “sparse rule base” simultaneously, an initial idea of hierarchical bidirectional fuzzy interpolation is presented in this article, combining hierarchical fuzzy systems and forward/backward fuzzy rule interpolation. In particular, backward fuzzy interpolation can be employed to allow interpolation to be carried out when certain antecedents of observation variables are absent, whereas conventional methods do not work. Hierarchical bidirectional fuzzy interpolation is applicable to situations where a multiple multi-antecedent rules system needs to be reconstructed to a multi-layer fuzzy system and any sub-layer rule base is sparse. The implementation of this approach is based on fuzzy rule interpolative reasoning that utilities scale and move transformation. An illustrative example and application scenario are provided to demonstrate the efficacy of this proposed approach.
Surface Finite Element for Imperfect Interface Modeling in Elastic Properties Homogenization
Authors: Sokolov Alexander Pavlovich , Schetinin Vitaliy Nikolaevich , Kozlov Mikhail Yurievich
Published: March 2020

The paper presents a mathematical model of a finite element for modeling imperfect interface conditions for two contacting surfaces. The element is used in the numerical implementation of the Asymptotic Averaging Method (AAM) for the determination of effective elastic properties of composite materials under investigation. Numerical experiments are carried out to calculate the elastic properties taking into account the adhesion layer using a displacements field jump condition at the phase boundary. Results are compared with adhesion modeling using an additional bulk phase.
Performance of D-Limonene/Ethanol in the Selective Recovery of PE from LDPE/VMPET/PET Laminates
Authors: Escasa Karl Vincent H. , Alindayu Ricardo II C. , Riña Gabrielle Mae G. , Mopon Jr. Marlon L. , Tumolva Terence
Published: March 2020

The prevalent sachet economy in the Philippines has led to the country becoming the third largest polluter of oceans in the world. The sachets used for packaging are made of plastic laminates which typically consist of varying polymeric layers combined with other modifiers to improve barrier properties. In this study, applicability of D-limonene and ethanol as solvent/non-solvent pair for the separation of polyethylene (PE) from vacuum-metallized polyethylene terephthalate (VMPET) and polyethylene terephthalate (PET) was established. PE recovery from LDPE/VMPET/PET laminates were calculated to be 50.79% w/w.
Electrochemical Immunosensor Based on Highly Sensitive Amino Functionalized Graphene Nanoplatelets-Modified Screen Printed Carbon Electrode
Authors: Badruzaman Nurul Azurin , Mohd Azmi Mohd Azraie , Said Nur Azura Mohd
Published: March 2020

We presented here the development of an immunosensor based on graphene nanoplatelets-modified screen printed carbon electrode (SPCE) with incorporated rabbit IgG on the amino functionalized surface area. In order to improve sensitivity of working electrode, graphene-nanoplatelets solution was fabricated onto surface carbon working electrode. The effect of different (3-aminopropyl) triethoxysilane (APTES) concentrations (0.125, 0.5, 2 and 8% (v/v)) and incubation time of silanization (30, 60 and 90 min) were studied and compared. An electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) were used to characterize our immunosensor based. It is showed that the optimum APTES concentration which provides higher surface coverage and electron transfer rate was 2% concentration (v/v) at 60 min of incubation time. The modified surface was then evaluated by measuring immobilized rabbit IgG via indirect assay using horseradish peroxidase labelled secondary antibody. The optimum detection immobilized IgG was 0.05 mg/mL. These results indicate the potential for amino functionalized graphene nanoplatelets-modified SPCE in detecting protein biomarkers.
Buckling Analysis of Stiffened Cone-Cylinder Intersection Subjected to External Pressure
Authors: Ismail Mohd Shahrom , Ifayefunmi O. , Md Fadzullah Siti Hajar Sheikh
Published: March 2020

This paper aims to examine the influence of ring stiffener reinforcement on the buckling behavior of cone-cylinder intersection subjected to external pressure. Three different stiffener locations were analyzed; they are (i) cone-cylinder intersection, (ii) cone mid-section, and (iii) cylinder mid-section. Internal and external stiffeners are used in the study. Buckling strength of the stiffened cone-cylinder intersections were obtained with the aid of FE analyses for all the cases above. Cone-cylinder intersections are modelled as elastic-perfectly plastic of Hiduminium alloy (HE-15). Validations of the present results with the published experimental data were presented. Result indicates that the introduction of stiffener reinforcement in externally pressurized cone-cylinder intersections seemed to be desirable in a preliminary design process, thus promotes a stronger shell to resist buckling.
Preliminary Study of Corrosion Behavior on Carbon Steel Rebar in Mortar Mixed with Tin Slag as Partial Substitute Cementious Material under 3.5% NaCl Environment Using Electrochemical
Authors: Ashari Afif Shidqi , Cahyadi Agung , Riastuti Rini
Published: March 2020

Tin slag is one of smelting waste that has not been utilized yet. As substitutional, cementious material in concrete replaced the function due to its similar oxide existence with Ordinary Portland Cement (OPC) such as SiO2, CaO, Al2O3, and Fe2O3. The objective of this research is to evaluate the corrosion behavior on the surface of carbon steel rebar due to the effect of partial substitution of tin slag in mortar. In this research, final tin slag added with ratio of 0.1, 0.2, 0.3 from total cement. The concrete had been cured for 28 days of immersed in NaCl 3.5% solution for 6 days. The corrosion behavior against steel reinforcement inside concrete measured by Electrochemical Impedance Spectroscopy (EIS) method and the result shows that 20% tin slag from the total of cement give the most competitive corrosion resistance than the others.
The Effect of Stand - Off Distance on the Mechanical Properties of TIG Butt Joints of 316 Stainless Steel
Authors: Gnedi Hala M. , Snoussi Khawla T. , Taher Abulmaali M.Y. , Sharef Thoria G. , Arebi Yousef
Published: March 2020

The objective of this study is to investigate and determine the effect of the stand-off distance (distance between the welded plates) on the mechanical properties of the Tungsten Inert Gas (TIG) welded joints. Butt TIG welding was performed for 316 stainless steel (SS) by using different pre welding stand-off distances with fixing the other parameters (thickness of welded plates, voltage, current, groove shape, and scanning speed). The influence of the stand-off distance parameter was examined by using tensile test, hardness test in the three different regions (base metal, heat effected zone, and molten zone), non-destructive testing (including visual inspection, liquid pentrant and X – ray) and microscopic examinations. Results show that the stand-off distance is one of the most important geometrical parameters of the Butt welded joints to end by good mechanical properties. It is found that the optimum stand-off distance was about 1 mm (shows the highest hardness results), but still there were some defects in some spots in the molten metal zone which caused a decrease in the hardness values in these locations. The 2 mm stand-off distance shows reasonable results, and the worst case was recorded for the 0 mm stand-off distance condition. Generally the hardness values of the heat affected zone in all conditions were the highest when compared to both metal welding zone and the base metal zone.
Mechanical Properties Research of Carbon Fiber Composite Laminates
Authors: Zhao Hong Wang , Liu Xiao Gang , Kent Abraham
Published: March 2020

This paper expounds the basic theory of composite mechanics, and discusses the damage forms, damage analysis and failure criteria of composite materials. Then, the basic mechanical properties of unidirectional CFRP laminates with different layers, including modulus of elasticity, strength and so on, were obtained through a large number of experiments. Based on the experimental data, the relationship between the number of layers and the properties of materials was studied. The brittle fracture process of CFRP laminates was simulated by finite element analysis based on progressive damage model and compared with the force-displacement curves obtained by experiments. The validity of progressive damage model was proved.
A Literature Review of Bacterial Drug Resistance
Authors: Wang Zi Qi
Published: March 2020

This paper summarizes the use of antibiotics and the current situation of bacterial resistance and explores the specific causes of bacterial resistance. Several commonly used and emerging detection techniques are described and compared. Finally, several measures and methods to reduce bacterial resistance are proposed.
Application of Biological Target Fishing Technology in Drug Discovery
Authors: Ye Xian Zhi
Published: March 2020

Target fishing, a cutting-edge technology for drug research and development, plays a significant role in drug discovery. Varieties of methods for finding small-molecule drug targets have come into being driven by genomics, proteomics, bioinformatics and other technologies. These new methods are mainly based on the expression of gene or protein and proteins properties, including affinity and stability and so on. A serious challenge for the most widely used small molecule drugs is the discovery and identification of biological (and potential therapeutic) targets. Herein, we enumerate five biological target fishing techniques, including surface plasma resonance (SPR) techniques, random photo modified probes, drug affinity responsive target stability, fishing-rod strategy, and photo affinity labeling. And then we introduces the principles of operation, practical applications in the biological field of five methods, and analysis of their shortcomings.
Analysis of Building Construction Materials and Environmental Technology of Labrang Monastery
Authors: Gao Qi , Meng Xiang Wu , Luo Dai Wei , Whitehand J.W.R.
Published: March 2020

Labrang Monastery is the only main monastery of the Gelug Sect of Tibetan Buddhism in Gannan area. From the perspective of building materials and technology, this paper carries out literature research and fieldwork in order to comb and summarize the main construction of monastery buildings and common building materials. Furthermore, it systematically analyses the architectural phisics, (acoustics, optics and thermotics) of monastery buildings via methods such as research, servey and data analysis. These above have positive referential value for the protection and renovation of Labrang Monastery and the modern design of regional religious buildings as well.
Permeable Brick Material and Process Selection Based on Sponge City Construction
Authors: Wei Zi Yao
Published: March 2020

Based on the background of sponge city, this paper discusses the necessity of studying permeable bricks from the permeable pavement, reviews the research on permeable bricks of industrial waste in China and abroad. Based on the mutual exclusion of materials and permeable bricks, a comparative analysis was carried out. Finally, the optimal permeable brick bricking method and a new type of cementing material—geopolymer were proposed.
Experimental Study on Effect of Disc Form on Soil Failure State of Expanded Piles under Horizontal Force
Authors: Qian Yong Mei , Song Yu Chen , Jin Yu Jie , Moshoeshoe Thato Molomo Pius
Published: March 2020

In this paper, test method of half-section small-scale model with indoor undisturbed soil is used to study the effect of difference disc forms on bearing mechanism of concrete disc piles and soil failure state around piles under horizontal force. The model piles with different disc cross-section forms were designed under the condition of undisturbed soil, and loading test was carried out to analyze soil failure state around the pile. The results show that: under the action of horizontal force, soil around the pile is cracked along the midline; asymmetric bearing disc is more reasonable than symmetrical bearing disc. The minimum load difference between the disc end fillet and the disc tip fillet is less than 5%. The curved end of bearing disc has little effect on the horizontal bearing capacity of concrete expanded disc pile.
Study on Microscopic Characteristics and Physical and Mechanical Parameters of Carbonaceous Rocks
Authors: Luo Jun Hui , Mi De Cai , Ye Qiong Yao , Sun Guan Hua , Chen De Qiang
Published: March 2020

In order to study the distribution of carbonaceous rocks in Guangxi, and reveal the microstructure of carbonaceous rocks, and explore the laws of physical and mechanical properties of carbonaceous rocks, and study the characteristics of carbonaceous rocks, the Regional division of the typical carbonaceous rocks in Guangxi was carried out. Subsequently, an electron microscopy scan test was conducted to analyze the microstructure characteristics of carbonaceous mudstone, shale and limestone. At the same time, the mineral composition of the carbonaceous rock, the chemical composition test was analyzed, and the physical and mechanical parameters test was conducted. Finally, the microscopic classification of carbonaceous rocks was linked to the physical and mechanical parameters. The results show that: (1) Guangxi carbonaceous rocks can be divided into three typical areas: Hechi District, Baise District and Liuzhou District. (2) The microstructure of carbonaceous limestone in Guangxi was mostly scaly, the mineral crystals of carbonaceous mudstone microstructure were mainly petal-like, and the clay minerals of carbonaceous shale microstructure was striped. (3) The microscopic chemical elements of Guangxi carbonaceous rocks were mainly carbon, silicon, and mineral components were mainly illite, and the illite content was linear with density.
Process Simulation of Carboniferous Volcanic in Jinlong Area, Junggar Basin
Authors: Wang Ya Ning , Ma Yu Chen , Li Gan Lu , Fahmita Rini
Published: March 2020

The Jinlong area is located in the northwestern margin of Junggar Basin. Volcanic is widely distributed in Carboniferous layers, showing well petroleum resources prospects. The distribution of volcanic reservoirs is obviously controlled by the distribution characteristics of volcanic lithofacies. Therefore, through the analysis of core observation, thin section identification, data of well logging and mud logging, and interpretation of seismic data, this paper studies process simulation of Carboniferous volcanic in the Jinlong area, which is located in the northwestern margin of Junggar Basin. Based on the characteristics of volcanic materials and comparison of profile facies, the paper restores distribution characteristics of lithofacies of Carboniferous in the study area: The study area mainly develops volcanic lithofacies such as effusive phase and explosive phase. The thickness between wells varies greatly, which is affected by eruption mode and fault development. The vertical and horizontal changes of lithofacies are discontinuous and the phase transformation is fast. The volcanic activity of Carboniferous gradually weakened. There are multiple volcanic eruption centers in each period, which are controlled by crack and distributed in beads. In addition, an intermediate-mafic composite volcanic-crack eruption edifice was developed in the southern zone of the study area. Because of strong tectonism in the area near the crater, there are many dissolvable components in volcanic, which can form favorable hydrocarbon reservoir bodies and become the most favorable target zone in the Jinlong area.
Air Purification System on Reduction of CO2 Concentration Using Low Temperature Liquefaction
Authors: Cao Wen Sheng , Bluth Christoph
Published: March 2020

For a closed working environment, the CO2 content in the air in a closed space will rise continuously due to personnel breathing and some equipment or electronic devices, and even exceed the allowable content in the normal working environment. In order to prevent the CO2 content from exceeding the standard in the closed working environment, the method of low temperature liquefaction is used to separate the CO2 in the air. Through simulation calculation and comparison of key parameters of the process of using cascade liquefaction and nitrogen expansion liquefaction to reduce CO2 concentration in air, it is concluded that it is feasible to use cryogenic liquefaction method to separate carbon dioxide from air to purify air and improve air quality in confined space.
A Spontaneous RAG1 Nonsense Mutation Unveils Naturally Occurring N-Terminal Truncated RAG1 Isoforms
Authors: Burn Thomas N , Lee Kyutae D , Dawany Noor , Robertson Tanner F , Fisher Megan R , Bassing Craig H , Behrens Edward M
Published: March 2020

The RAG1 and RAG2 proteins are essential for the assembly of Ag receptor genes in the process known as VDJ recombination, allowing for an immense diversity of lymphocyte Ag receptors. Congruent with their importance, RAG1 and RAG2 have been a focus of intense study for decades. To date, RAG1 has been studied as a single isoform; however, our identification of a spontaneous nonsense mutation in the 5′ region of the mouse Rag1 gene lead us to discover N-truncated RAG1 isoforms made from internal translation initiation. Mice homozygous for the RAG1 nonsense mutation only express N-truncated RAG1 isoforms and have defects in Ag receptor rearrangement similar to human Omenn syndrome patients with truncating 5′ RAG1 frameshift mutations. We show that the N-truncated RAG1 isoforms are derived from internal translation initiation start sites. Given the seemingly inactivating Rag1 mutation, it is striking that homozygous mutant mice do not have the expected SCID. We propose that evolution has garnered RAG1 and other important genes with the ability to form truncated proteins via internal translation to minimize the deleterious effects of 5′ nonsense mutations. This mechanism of internal translation initiation is particularly important to consider when interpreting nonsense or frameshift mutations in whole-genome sequencing, as such mutations may not lead to loss of protein.
Ultra sound as I see it
Authors: Wood E. J.
Published: March 2020

No abstract avialable.
The use of Entonox in conjunction with the physiotherapy treatment of burns
Authors: Runnalls M. J. , Stephan M. W.
Published: March 2020

No abstract available.
Unusually long survival of an adult patient with atypical teratoid/rhabdoid tumor of the sellar region: A follow-up report
Authors: Almalki Mussa , Altwairgi Abdullah , Orz Yasser
Published: March 2020

Atypical teratoid/rhabdoid tumor (AT/RT) is a rare and very aggressive central nervous system neoplasm that is most often seen in infants and young children. The prognosis remains poor, with a median survival time of <1 year. Here, we report a follow-up on a case of AT/RT that originated in the sellar and suprasellar region in a 42-year-old female patient with unusually long survival.