bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effects of Irrigation and Nitrogen Application on the Water and Nitrogen Utilization Characteristics of Drip-Irrigated Winter Wheat in the North China Plain
Authors: Qin Jingtao , Fan Xichao , Wang Xiaosen , Jiang Mingliang , Lv Mouchao
Published: November 2024

Reducing irrigation and nitrogen fertilizer application while maintaining crop yields is crucial for sustainable agriculture in the North China Plain. To investigate the effects of irrigation and nitrogen application on above-ground nitrogen accumulation (ANA), yield, water consumption, and the water and nitrogen use efficiency of drip-irrigated winter wheat, a three-season field experiment was conducted with four levels of nitrogen fertilizer application (250, 167, 83, and 0 kg hm−2, referred to as N3, N2, N1, and N0, respectively) and three levels of irrigation (80, 60, and 40 mm per irrigation event, referred to as W3, W1, and W1, respectively). Additionally, a control treatment (CK) was set up with almost no irrigation (only 10 mm of fertilizer water for topdressing was applied) at the N3 application level. The results indicated that over the three seasons, the average yield of irrigation treatments was 35.3% higher than that of the CK treatment under the N3 condition. Both irrigation and nitrogen application improved wheat yield and ANA; however, when irrigation exceeded W2 or nitrogen application exceeded N2, their positive effects were negligible. Due to the seasonal depletion of soil nitrogen by low-nitrogen treatments (N1 and N0), along with their other negative effects on soil health, the yields and ANA of N1 and N0 treatments gradually declined over seasons. Increased irrigation promoted evapotranspiration (ET), and when nitrogen application did not exceed N2, higher nitrogen levels also enhanced ET and soil water consumption within ET. Moderately reducing irrigation can enhance water use efficiency (WUE); however, extreme water scarcity can also decrease WUE. Compared to higher irrigation and nitrogen application treatments, the W2N2 treatment showed no significant decrease in either yield or WUE, along with an increase in NPE. Moreover, the NPFP of the N2 treatment was higher than that of the N3 treatment. Consequently, the W2N2 treatment is recommend as the optimal irrigation and nitrogen management strategy under the experimental conditions.
Characterization of Serpin Family Genes in Three Rice Planthopper Species and Their Expression Profiles in Response to Metarhizium Infection
Authors: Zhang Ruonan , Zhong Zichun , He Liyan , Wu Hongxin , He Liuyan , Guo Yujing , Wu Haoming , Xu Xiaoxia , Jin Fengliang , Pang Rui
Published: November 2024

Rice planthoppers, including Nilaparvata lugens, Sogatella furcifera, and Laodelphax striatellus, are major agricultural pests. Serpins, which function as serine protease inhibitors, play a pivotal role in the immune systems of these insects, especially within the Toll signaling pathway and the prophenoloxidase (PPO) cascade. This study presents a comparative analysis of serpin genes among these species, highlighting their roles in immunity and development. Utilizing genomic and bioinformatics approaches, we identified 11, 11, and 14 serpin genes in N. lugens, S. furcifera, and L. striatellus, respectively. Phylogenetic analysis revealed a close evolutionary relationship between these serpin genes and Bombyx mori BmSerpins, emphasizing the functional diversity of the serpin family. Structural analysis confirmed the presence of the reactive center loop (RCL) in all serpin proteins, with the Serpin7 subfamily showing a unique dual RCL configuration. Expression profiling showed species-specific serpin expression patterns across different life stages and adult tissues. Moreover, transcriptional analysis of serpin genes in the three planthoppers following Metarhizium infection uncovered distinct immune regulatory patterns two days post-infection. Notably, the expression of NlSerpin2-2/6, SfSerpin4/6/7-1, and LsSerpin4/5-2/6 was upregulated post-infection, potentially enhancing antifungal capabilities. In contrast, the expressions of NlSerpin1/7-1/9 and LsSerpin1/2/3/8/13 were downregulated, possibly suppressing immune responses. Moreover, Serpin6s, which share a conserved phylogenetic lineage, exhibited enhanced immune activity in response to fungal invasion. These insights into serpin-mediated immune regulation could contribute to the development of novel pest-control strategies.
Self-Reported Antibiotics Usage, Allergies and Resistance of Albanian Patients from a Dental Perspective: A Preliminary Questionnaire-Based Survey
Authors: Zeza Blerina , Kraja Nisrina , Disha Valbona , Cenameri Erdita , Bardhoshi Esat
Published: November 2024

Objectives: The paper aims to assess the level of antibiotic use and the antibiotic types used generally in dentistry and identify self-reported allergies and resistance related to them. Methods: The data were collected between March and May 2024 via an electronic questionnaire on self-reported antibiotic usage, antibiotic allergies and resistances among individual in Albania. Results: A total of 477 individuals (83% females, 17% males) with a mean 33 ± 13 (min 17; max 73) years of age completed the questionnaire. Overall, 88% of the population reported having used antibiotics before the questionnaire, among whom 56% used them for dental reasons. An average of 5% reported being allergic, mainly to the penicillin group, while 5% claimed to have undergone an antibiogram analysis before taking the prescribed antibiotics, with most of them showing resistance to the penicillin group. Conclusions: Based on the findings of this study, the high prevalence of antibiotics usage in dentistry encourages further deepening studies and training adapting global guidelines for antibiotics indications in dentistry to the level of antibiotics allergies and resistances of this specific country.
What Is the Role of Local Antimicrobial Protection for One-Stage Revision for Peri-Prosthetic Hip Infection?
Authors: Romanò Carlo Luca , Bonomo Luigi , Bonomo Giulio , Viale German , Del Sel Hernán , Tezval Mohammad
Published: November 2024

The aim of this review is to investigate the effective role of local antimicrobial protection for one-stage cemented and cementless hip revision surgery. Twelve studies reporting the results of cemented single-stage procedures with a minimum two-year follow-up were reviewed. When pooling together the data, no infection recurrence was observed on average in 83.3% of the patients (a range of 75.0% to 100%). Only two papers included patients treated without the use of antibiotic-loaded bone cement, with an average infection control of 95.9% in a total of 195 patients. This figure appears to be better than the 80.7% infection control obtained by pooling together all the remaining studies. Concerning cementless one-stage revision, a total of 17 studies, reporting on 521 patients, showed an average of 90.0% (range 56.8% to 100%) no infection recurrence at a minimum two-year follow-up. No comparative study investigated cementless revision with or without local antibacterial protection. The pooled data showed an average infection control of 86.7%, without the application of local antibacterials, compared to 90.1% to 100% with local antimicrobial protection, depending on the technology used. No statistical difference could be found, either considering local antibacterial strategies alone or pooled together. No side effects had been reported by any local antibacterial technique. Local antibacterial protection for one-stage hip revision surgery, although safe and largely performed in the clinical setting, appears to still rely mainly on experts’ opinions with no prospective or comparative trial, hence no definitive conclusion can be drawn concerning its effective role in one-stage hip revision surgery.
Antioxidative Status and Meat Quality Traits as Affected by Dietary Supplementation of Finishing Pigs with Natural Phenolics
Authors: Muzolf-Panek Małgorzata , Zaworska-Zakrzewska Anita , Czech Anna , Lisiak Dariusz , Kasprowicz-Potocka Małgorzata
Published: November 2024

This work investigated the effect of a plant-based phenolic supplement on the color, myoglobin forms, lipid oxidation, and antioxidative status of fresh and stored (10 days at 4 °C) meat (Longissimus thoracis et lumborum), as well as the antioxidative status of the blood and liver. The sensory quality of the meat was also evaluated for color, aroma, texture, juiciness, and palatability. Twenty-four finishing pigs, divided into two groups, were fed a basal diet and a diet with a phenolic supplement (0.1%). The supplementation increased the redness of the meat (+36% for a* and +28% for redness index), the myoglobin (Mb) content (+7%), the antioxidant activity, and the juiciness. The treatment increased the antioxidant status of meat, reflected by superoxide dismutase (SOD) activity and total glutathione (GSH + GSSG). The catalase and SOD activities and GSH + GSSG of the blood and liver were also elevated in the supplemented samples when compared to the control group. A significant effect of time was observed for all tested parameters (pH, color attributes, Mb forms, the antioxidant activity, lipid oxidation) except for the Mb content. For the stored samples, only TBARSs (thiobarbituric acid reagent substances) were affected by the diet. The slope of the plot for TBARS changes with time was significantly different between the control and treated groups (p = 0.017), which indicated a significant effect of dietary supplementation. A higher rate of lipid oxidation was observed in the control samples.
Role of Plant Phytochemicals: Resveratrol, Curcumin, Luteolin and Quercetin in Demyelination, Neurodegeneration, and Epilepsy
Authors: Grabarczyk Mikołaj , Justyńska Weronika , Czpakowska Joanna , Smolińska Ewa , Bielenin Aleksandra , Glabinski Andrzej , Szpakowski Piotr
Published: November 2024

Polyphenols are an important group of biologically active compounds present in almost all food sources of plant origin and are primarily known for their anti-inflammatory and antioxidative capabilities. Numerous studies have indicated their broad spectrum of pharmacological properties and correlations between their increased supply in the human diet and lower prevalence of various disorders. The positive effects of polyphenols application are mostly discussed in terms of cardiovascular system well-being. However, in recent years, they have also increasingly mentioned as prophylactic and therapeutic factors in the context of neurological diseases, being able to suppress the progression of such disorders and soothe accompanying symptoms. Among over 8000 various compounds, that have been identified, the most widely examined comprise resveratrol, curcumin, luteolin and quercetin. This review focuses on in vitro assessments, animal models and clinical trials, reflecting the most actual state of knowledge, of mentioned polyphenols’ medicinal capabilities in epilepsy, demyelinating and neurodegenerative diseases of the central nervous system.
Reliability of a Portable Fixed Dynamometer During Different Isometric Hamstring Assessments
Authors: Woodbridge Ryan , Ryan Chloe , Burkitt Josh , Ye-Lee Dana , Cronin John
Published: November 2024

Hamstring strain injuries are one of the most common non-contact injuries in sport. Hamstring strength and asymmetry are two key modifiable risk factors for hamstring strain injuries; therefore, it seems important to find reliable tests for assessing hamstring strength. The purpose of this study was to determine the within- and between-session reliability of a portable fixed dynamometer for measuring hamstring strength using three different protocols. Fourteen male participants completed three hamstring isometric protocols across three testing occasions separated by seven days. Peak force, mean force and impulse all had good to excellent within- and between-session reliability for the standing hamstring, supine 90:90 and standing 90:20 assessment (CV = 2.6–11.7%, ICC = 0.74–0.99), while peak rate of force development had moderate to excellent relative consistency (ICC = 0.64–0.90) and unacceptable absolute consistency (CV = 17.1–36.6%). The 90:20 assessment produced significantly higher values (33.4–47.3%) compared to the standing and 90:90 assessments for peak force, mean force and impulse. It appears that a portable fixed dynamometer can reliably measure a range of force–time metrics during three different hamstring assessments; however, the results of the tests cannot be used interchangeably and practitioners comparing hamstring force capability between individuals/research studies need to be cognizant of this and proceed with caution.
Exploring Multisource Remote Sensing for Assessing and Monitoring the Ecological State of the Mountainous Natural Grasslands in Armenia
Authors: Ayvazyan Grigor , Muradyan Vahagn , Medvedev Andrey , Khlghatyan Anahit , Asmaryan Shushanik
Published: November 2024

Remote sensing (RS) is a compulsory component in studying and monitoring ecosystems suffering from the disruption of natural balance, productivity, and degradation. The current study attempted to assess the feasibility of multisource RS for assessing and monitoring mountainous natural grasslands in Armenia. Different spatial resolution RS data (Landsat 8, Sentinel-2, Planet Scope, and multispectral UAV) were used to obtain various vegetation spectral indices: NDVI, NDWI, GNDVI, GLI, EVI, DVI, SAVI, MSAVI, and GSAVI, and the relationships among the indices were assessed via the Spearman correlation method, which showed a significant positive correlation for all cases (p < 0.01). A comparison of all indices showed a significant high correlation between UAV and the Planet Scope imagery. The comparisons of UAV with Sentinel and Landsat data show moderate and low significant correlation (p < 0.01), correspondingly. Also, trend analysis was performed to explore the spatial–temporal changes of these indices using Mann–Kendall statistical tests (MK, MKKH, MKKY, PW, TFPW), which indicated no significant trend. However, Sen’s slope as a second estimator showed a decreasing trend. Generally, it could be proved that, as opensource data, Sentinel-2 seemed to have better alignment, making it a reliable tool for the accurate monitoring of the ecological state of small mountainous grasslands.
A Method to Improve Underwater Positioning Reference Based on Topological Distribution Constraints of Multi-INSs
Authors: Xiong Yuyu , Yang Gongliu , Wen Zeyang
Published: November 2024

This study investigates a data fusion method for underwater multi-inertial navigation based on topological distribution constraints, aimed at improving the positional accuracy of navigation systems on ships, and generating an underwater position reference. First, the state equation of single-axis rotational inertial navigation system (SRINS) is introduced to compensate for the equivalent gyroscope zero bias caused by gravity and magnetic field. Second, a flexible lever error equation based on the influence of flexural deformation angles between SRINSs is proposed. Third, by using the position difference between SRINSs as a measurement, the state and measurement equations of a centralized Kalman filter are analyzed. We conducted two sets of car experiments to verify the proposed data fusion method and a data acquisition system was used to synchronously collect measurement data from three SRINSs. Experimental results show that the proposed method can effectively improve overall positioning accuracy, with the root mean square (RMS) of longitude error reduced by approximately 8.4360%, latitude error RMS reduced by approximately 6.9174%, and overall positioning error RMS reduced by approximately 9.9492%. In certain conditions where other positioning methods are unavailable, such as underwater navigation, the proposed RINSs data fusion method can provide a highly reliable position reference.
An ICN-Based Delay-Sensitive Service Scheduling Architecture with Stateful Programmable Data Plane for Computing Network
Authors: Wei Ranran , Han Rui
Published: November 2024

The Computing Network is an emerging paradigm that integrates network and computing resources. One of its goals is to satisfy the requirements of delay-sensitive services through network scheduling capabilities. However, traditional TCP/IP networks are deficient in accurately being aware of requirements and performing flexible routing based on service levels. Information-Centric Networking (ICN) addresses these issues through its flexible protocol design and content-based routing mechanism. Additionally, the integration of Software-Defined Networking (SDN) technology further enhances its routing flexibility. Therefore, this paper proposes an ICN-based delay-sensitive service scheduling architecture with an SDN stateful programmable data plane. The network nodes are first layered based on the type of computing clusters they are linked with, and then within each layer, they are divided into several domains according to delay constraints. Then, the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) algorithm, combined with the Best-Worst Method (BWM) weighting method, is adopted to evaluate the candidate clusters, and the corresponding scheduling strategy is executed in the stateful programmable data plane. The simulation results show that compared with other scheduling architectures and traditional TOPSIS with the Entropy Weight Method (EWM), the proposed architecture and algorithm show significant advantages in reducing the overall delay of service requests and improving the scheduling success ratio, as well as the load balance of the computing clusters.
The Diagnostic Accuracy of Overnight Oximetry for Pediatric Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis
Authors: Incerti Parenti Serena , Bartolucci Maria Lavinia , Fiordelli Andrea , Gigola Pierangelo , Paganelli Corrado , Alessandri-Bonetti Giulio
Published: November 2024

Polysomnography (PSG) is the gold standard for the diagnosis of pediatric obstructive sleep apnea (OSA); however, high costs and limited availability restrict its use for routine screening. This systematic review and meta-analysis investigated the accuracy of overnight oximetry for the diagnosis of pediatric OSA. Studies evaluating overnight oximetry against PSG-derived apnea-hypopnea index (AHI) in subjects aged ≤18 years were considered in the qualitative analysis and evaluated with the QUADAS-2 tool. Only oximetry parameters adopted by at least four studies using the currently accepted diagnostic thresholds for pediatric OSA (AHI of 1, 5 and 10 events/h) were included for quantitative analyses. A bivariate meta-analysis was used to estimate sensitivity and specificity, as well as to construct summary receiver operator characteristic curves. The positive and negative predictive values were calculated. A total of 28 studies (9122 participants) were included in qualitative analyses. Only 3% oxygen desaturation index (ODI3) was eligible for the quantitative analyses (six studies, 1276 participants). As OSA severity increases sensitivity, specificity and the negative predictive value also increase, reaching values of 79%, 84%, and 89% at AHI ≥ 10, respectively. Oximetry displays a good performance as a screening tool for pediatric OSA, especially with moderate-to-severe disease. ODI3 is particularly effective at ruling out OSA in children who test negative.
Enhancement of Skin Anti-Wrinkling Effects of Arthrospira maxima Phycocynobilin by Combining with Wheat Bran Extract
Authors: Koh Eun-Jeong , Kim Taeho , Ryu Yong-Kyun , Lee Won-Kyu , Sunwoo In-Yung , Ro Hyang Seon , Jeon Gibeom , Kim Gyu Rae , Lee Hyeon Yong , Choi Woon-Yong
Published: November 2024

Despite the many beneficial effects of phycocyanobilin (PCB) on human skin, its cosmetic applications have not been extensively investigated owing to its light and temperature sensitivity. This is the first report of PCB extract (SP) derived from marine Arthrospira maxima having skin anti-wrinkling effects associated with antioxidant efficacy and reduction of intracellular reactive oxygen species (ROS) production. We obtained 46.63 ± 1.72 mg PCB/g dry weight of A. maxima in SP through an ethanol extraction process. PCB extracts showed strong effects in increasing collagen synthesis and decreasing matrix metalloproteinases (MMP-1) production. Interestingly, skin anti-wrinkling effects of the PCB extracts were significantly increased by the addition of wheat bran extracts (WB), up to 20–30% of the effects of PCB at all concentrations, possibly due to the synergistic effects of soluble globulins and other active substances in WB. Moreover, the mixture of SP and WB (SPWB) greatly reduced cell cytotoxicity to approximately 15% of that of PCB. SPWB upregulated and downregulated the expression of collagen type I α1 (Col1A1) and MMP-1, respectively, although the downregulation of MMP-1 was higher than that of Col1A1. The optimal SPWB concentration for maintaining the highest skin anti-wrinkling effects was 0.5 mg/mL. We show that SPWB holds promise as a vegan cosmaceutical.
Theoretical Optimization Method of Tunnel Lining in Fractured Rock Mass Based on Rock Classification and Hoek–Brown Criterion
Authors: Shen Caihua , Zeng Zhikang , Zhu Jun
Published: November 2024

Considering the effect of surrounding rock on lining in the design of tunnel lining within fractured rock masses is challenging, particularly in accurately predicting the reserved deformation of the tunnel. This study bases a rock mass classification method and the established Hoek–Brown (H-B) strength criterion to assess the deformation characteristics of the surrounding rock. It establishes a more scientifically rigorous theoretical calculation method for the reserved deformation of tunnel linings that accounts for the rock–lining interaction. An optimization design approach for the lining structure, based on the synergistic effect and considering the stress safety of the concrete lining and the rock’s displacement release rate, is proposed. Case analysis is utilized to validate the safety of the lining design in the study section through computational verification. The recommended optimized lining parameters are identified: the support time is initiated when the tunnel wall’s surrounding rock deforms by 9 mm, and the lining thickness is optimized to 47 cm, which is approximately 36.5% less than the pre-optimization thickness. This precise optimization of support timing and lining thickness enhances both the safety and economic efficiency of the Wufengshan Tunnel. The method allows for the calculation of the optimal combination of support time and lining thickness tailored to different surrounding rock conditions, offering significant reference value for tunnel lining optimization.
Stakeholder Perspectives on Safety Issues in Collaborative Mobile Robots: A Case Study of Quadruped Robot Applications in a Smart Factory
Authors: Go Eutteum , Lee Jun Hyoung , Kim So Yeong , Lee Jong Sup , Kim Hyung Hwan , Lim Joong Yeon
Published: November 2024

With the development of Industry 4.0, collaborative mobile robots are becoming increasingly prevalent in industrial settings, raising important safety considerations in human–robot interaction environments. This study examines the safety issues in collaborative mobile robotics through a case study of a smart factory utilizing quadruped robots. This research aims to contribute to the development of safety management strategies by identifying potential risk factors and analyzing the differences in risk perception among stakeholders. A survey was conducted among 93 operators in the factory to identify the main risk factors, followed by a Delphi study with four groups of experts: robot operators, safety management experts, robot developers, and academic experts. The Kruskal–Wallis and Mann–Whitney U tests were used to analyze the statistical significance of differences in perception between the groups. The results showed that collision and deviation from the path were the most concerning risk factors. Significant differences were found in the perceptions of several hazards between expert groups, with academic experts rating most hazards highly while robot developers rated them relatively low. The findings highlight how background knowledge and experience influence risk perception in collaborative robotics. These varying perspectives should be considered when developing safety management strategies for mobile robots in industrial settings, suggesting the importance of multi-stakeholder collaboration and targeted educational programs.
Mineral Content in Initial and Follow-On Infant Formulas in Poland: Nutrient Adequacy and Comparison with Breast Milk
Authors: Purkiewicz Aleksandra , Mumtaz Wajeeha , Tońska Elżbieta , Pietrzak-Fiećko Renata
Published: November 2024

In the present study, the content of selected micro- and macrominerals in conventional and specialist infant formulas (IFs) available on the Polish market was assessed and compared with breast milk from different periods of lactation. The content of minerals was assessed against established standards, compared to label guidelines, and the estimated coverage of daily requirements for selected minerals among infants. The study material consisted of fourteen types of initial, follow-on, and specialist IFs. Minerals—Na, K, Ca, Mg, Fe, Zn, Cu, and Mn were determined by the atomic absorption spectroscopy (AAS) method and P—by colorimetric method. The specialist formula S1 stood out in terms of Ca, Mg, and Mn, and S6 in terms of Na and K compared to other IFs (p < 0.05). Human milk contained lower contents of each element relative to all infant formulas. Regarding the European Commission’s recommendations, most types of IFs met standards for mineral content. In 12 IFs, the marked Fe content was lower than that declared by the manufacturer, and the difference ranged from 5 to more than 50%. All of the initial and five specialist IFs covered the need for all minerals among infants, while follow-on reported coverage lower than standards for Mg, Na, K, Fe, and Mn. Infant foods should be strictly controlled, and periodic checks on the determination of levels of selected ingredients in IFs are recommended to obtain products that resemble human food to the highest possible degree.
Red Wines from Consecrated Wine-Growing Area: Aromas Evolution Under Indigenous and Commercial Yeasts
Authors: Niculescu Violeta-Carolina , Sandru Daniela , Botoran Oana Romina , Sutan Nicoleta Anca , Popescu (Stegarus) Diana Ionela
Published: November 2024

The aromatic profile of red wines is influenced by various factors, among them being distinguished the pedoclimatic ones, the variety, or the production technology. In the winemaking process, the use of different yeast strains can lead to obtaining wines with specific or conventional aromas (commercial strains), but also to the production of wines with a regional character using local strains. This study focuses on the analysis and comparison of the compounds that offer aromas in five wine varieties (Pinot noir, Feteasca Neagra, Burgund Mare, Syrah, and Novac) from Recaș, Romania, obtained through microvinification under the influence of several types of starter strains (Enartis Ferm SC, Viniferm Sensacion, SCR297, SCR462). The concentrations of polyphenols and anthocyanins, as well as their antioxidant activity, were monitored, resulting in significant values, mainly using autochthonous strains isolated from local plantations. A total of 30 aroma compounds were identified, maximum amounts being noted in the assortments where SCR297/SCR462 yeasts were used within the fermentation process. From a sensory point of view, a lower floral modulation was found when using commercial Enartis Ferm SC Saccharomyces cerevisiae yeasts. In conclusion, it the importance was demonstrated of isolated strains from the region used in fermentation processes, resulting in more aromatic and locally specific red wines.
Modeling and Compensation of Stiffness-Dependent Hysteresis Coupling Behavior for Parallel Pneumatic Artificial Muscle-Driven Soft Manipulator
Authors: Zhang Ying , Qi Huiming , Cheng Qiang , Li Zhi , Hao Lina
Published: November 2024

The parallel driving soft manipulator with multiple extensors and contractile pneumatic artificial muscles (PAMs) is able to operate continuously and has varying stiffness, achieving smooth movements and a fundamental trade-off between flexibility and stiffness. Owing to the hysteresis of PAMs and actuator couplings, the manipulator outputs display coupled hysteresis behaviors with stiffness dependence, causing significant positioning errors. For precise positioning control, this paper takes the lead in proposing a comprehensive model aimed at accurately predicting the coupled hysteresis behavior with the stiffness dependence of the soft manipulator. The model consists of an inherent hysteresis submodule, an actuator coupling submodule, and a stiffness-dependent submodule in series. The asymmetrical hysteresis nonlinearity of the PAM is established by the generalized Prandtl–Ishlinskii model in the inherent hysteresis submodule. The serial actuator coupling submodule is dedicated to modeling the actuator couplings, and the stiffness-dependent submodule is implemented with a fuzzy neural network to characterize the stiffness dependence and other system nonlinearities. In addition, an inverse compensator on the basis of the proposed model is conducted. Experiments demonstrate that this model possesses high accuracy and good generalization, and its compensator is effective in decoupling and mitigating hysteresis coupling of the manipulator. The proposed model and control methods significantly improve the positioning accuracy of the pneumatic soft manipulator.
Byproducts as a Sustainable Source of Cosmetic Ingredients
Authors: Machado Manuela , Silva Sara , Costa Eduardo M.
Published: November 2024

The cosmetic industry has been driven to implement sustainable practices that can help it overcome its high carbon footprint and intensive raw material extraction needs. The adoption of circular economy and bioeconomy concepts within the industry has been regarded as a solution for this problem, and within these concepts, byproducts’ incorporation in the cosmetics production chain, either as bioactive or as a structural component, is only a logical step. With this in mind, this review aims to provide an overarching view of the application of byproducts in cosmetics with emphasis not only on their potential biological properties but also on all the regulations and societal and economic impacts associated with byproducts’ incorporation into cosmetics and how they can help this industry.
The Effect of the Nordic Hamstring Curl Training Program on Athletic Performance in Young Football Players
Authors: Adıgüzel Niyazi Sıdkı , Koç Murat , Öztürk Barışcan , Engin Hakan , Karaçam Aydın , Canlı Umut , Orhan Bekir Erhan , Aldhahi Monira I.
Published: November 2024

Background: This study aimed to determine the effect of the Nordic hamstring curl training (NHCT) program on athletic performance elements such as linear speed, change of direction (COD), jump performance (CMJ), and eccentric muscle strength (Nordic Hamstring Curl Breaking Point Angle—NHCBP) in young football players. Methods: The study group consisted of 40 male football players who were actively trained and had no previous eccentric training experience or reported any injuries. The participants were randomly divided into a training group (TG = 20) and a control group (CG = 20). The TG performed the NHCT program twice a week for eight weeks, in addition to their standard football training. The CG continued with standard football training. Results: The study findings revealed no statistically significant differences in the interaction between group and time in 10, 20, and 30 m sprint performance. However, statistically significant differences were found in CMJ performance in terms of group–time interaction (F = 19.99, p < 0.001, η2 = 0.52), COD (F = 11.10, p < 0.004, η2 = 0.38), and NHCBP (F = 6.14; p < 0.02; η2 = 0.25). After the eight-week NHCT program, the experimental group showed improvements of 18% in CMJ performance, 8% in COD performance, and 25% in NHCBP performance. Conclusions: The NHCT program significantly increased hamstring muscle strength in football players, and this increase positively affected players’ linear speed and change of direction performance. NHCT has the potential to enhance athletic performance in football.
Emotion-Driven Music and IoT Devices for Collaborative Exer-Games
Authors: Álvarez Pedro , García de Quirós Jorge , Fabra Javier
Published: November 2024

Exer-games are interactive experiences in which participants engage in physical exercises to achieve specific goals. Some of these games have a collaborative nature, wherein the actions and achievements of one participant produce immediate effects on the experiences of others. Music serves as a stimulus that can be integrated into these games to influence players’ emotions and, consequently, their actions. In this paper, a framework of music services designed to enhance collaborative exer-games is presented. These services provide the necessary functionality to generate personalized musical stimuli that regulate players’ affective states, induce changes in their physical performance, and improve the game experience. The solution requires to determine the emotions that each song may evoke in players. These emotions are considered when recommending the songs that are used as part of stimuli. Personalization seeds based on players’ listening histories are also integrated in the recommendations in order to foster the effects of those stimuli. Emotions and seeds are computed from the information available in Spotify data services, one of the most popular commercial music providers. Two small-scale experiments present promising preliminary results on how the players’ emotional responses match the affective information included in the musical elements of the solution. The added value of these affective services is that they are integrated into an ecosystem of Internet of Things (IoT) devices and cloud computing resources to support the development of a new generation of emotion-based exer-games.
Sensitivity Analysis of Different Hydrothermal Characteristics in the Variable Thermodynamic Processes of Soft Clay Rock
Authors: Wang Tao , Lin Huixi , Ren Kexiong , Gao Jian , Wang Di
Published: November 2024

Artificial ground freezing technology is the most important construction method of complex water-bearing soft clay rock. The thermodynamic properties of soft clay rock are important evidence for the design and construction of space resources development, and the variable hydrothermal parameter can directly affect the uncertain thermodynamic properties of soft clay rock. In this work, an array of field experiments on the soft clay rock are carried out, and the anisotropic spatial variations of hydrothermal parameters of soft clay rock are obtained. The statistical variability characteristics of variable hydrothermal parameters are estimated. A stochastic coupling model of soft clay rock with heat conduction and porous flow is proposed, and the uncertain thermodynamic properties of soft clay rock are computed by the self-compiled program. Model validation with the experimental and numerical temperatures is also presented. According to the relationship between anisotropic spatial variations and statistical variability characteristics for the different random field correlation models, the effects of the autocorrelation function, coefficient of variation, and autocorrelation distance of variable hydrothermal parameters on the uncertain thermodynamic properties of soft clay rock are analyzed. The results show that the proposed stochastic analysis model for the thermal characteristics of soft clay rock, considering the spatial variability of frozen soil layers, is scientifically reasonable. The maximum standard deviation of average thickness is 2.33 m, and the maximum average temperature is 2.25 °C. For the autocorrelation function, the most significant impact comes from DBIN. For the coefficient of variation, the most significant impact comes from thermal conductivity. Different variations of hydrothermal parameters have different effects on the standard deviation of soft clay rock temperature. The biggest influence is the thermal conductivity, while the lowest influence is the specific heat capacity.
Mechanical Sealing Method for Laboratory-Scale Hydraulic Fracturing Tests of Granite Rocks Under High-Temperature and High-Pressure Conditions
Authors: Hongwei Zhang , Zhaoying Chen , Chuanhong Zhou , Qingshuai Yang , Xusheng Rui , Shijun Wang
Published: November 2024

Deep hot dry rock (HDR) geothermal energy is a widespread and sustainable renewable energy that could be extracted for the decarbonisation of electricity generation. Measurements are essential for hydraulic fracturing in HDR monitoring, which can be used for assessing the current state and predicting the future performance of geothermal systems. However, a major challenge is that it is difficult to implement hydraulic fracturing for HDR under high-temperature and high-pressure (HTHP) conditions. Similarly, it is hard to conduct laboratory-scale hydraulic fracturing experiments under HTHP due to the sealing failure of injection pipes in boreholes. Therefore, in this paper, we proposed a novel sealing technique by using a wedge-shaped structure for sealing injection pipes under HTHP environments. By conducting numerical simulations and experimental verifications, we discovered that (1) compression stress should be applied on the seal to achieve pre-sealing. Specifically, a compression displacement of between 2 mm and 6 mm is suggested. (2) Copper material with good ductility, high-temperature bearing performance, and excellent thermal expansion is preferred for manufacturing the seal components. (3) Heating-induced thermal expansion of sealing is conducive to re-sealing rocks.
Enhanced Short-Term Temperature Prediction of Seasonally Frozen Soil Subgrades Using the NARX Neural Network
Authors: Zeng Chao , Liu Xiao , Chen Liyue , He Xianzhi , Kang Zeyu
Published: November 2024

Accurate prediction of subgrade temperatures in seasonally frozen regions is crucial for understanding thermal states, frost heave phenomena, stability, and other critical characteristics. This study employs a nonlinear autoregressive with exogenous input (NARX) network to predict short-term subgrade temperatures in the Golmud-Nagqu section of China’s National Highway 109. The methodology involves preprocessing subgrade monitoring data, including temperature, water content, and frost heave, followed by developing a temperature prediction model. This tailored NARX neural network, compared to the traditional BP neural network, integrates feedback and delay mechanisms for monitoring data, offering superior memory and dynamic response capabilities. The precision of the NARX model is assessed with the backpropagation (BP) network, indicating that the NARX neural network significantly outperforms the BP model in both precision and stability for temperature prediction in seasonally frozen subgrades. These findings suggest that the NARX model is a valuable tool for accurately predicting subgrade temperatures in seasonally frozen regions, offering significant insights for practical engineering applications.
Analysis of Fractional Resonant Controllers for Voltage-Controlled Applications
Authors: Heredero-Peris Daniel , Lledó-Ponsati Tomàs , Chillón-Antón Cristian , Montesinos-Miracle Daniel , Melendez-Frigola Joaquim
Published: November 2024

This paper investigates the application of fractional proportional–resonant controllers within the voltage control loop of grid-forming inverters. The use of such controllers introduces an additional degree of freedom, enabling greater flexibility in manipulating frequency trajectories. This flexibility can be harnessed to improve tracking error and enhance disturbance rejection, particularly in applications requiring precise voltage regulation. The paper conducts a conceptual stability analysis of ideal fractional proportional–resonant controllers using the Nyquist criterion. A tuning procedure based on robustness criteria for the proposed controller is also addressed. This tuning strategy is used to compare different controllers under the same conditions. In addition, a sensitivity analysis is provided, comparing the performance of fractional proportional–resonant controllers with traditional proportional–resonant controllers equipped with harmonic compensation. The controller’s formulation and performance are validated through simulations and tested with a 20 kVA inverter under high non-linear loads. Compared to classical control approaches, the fractional tuning parameter enhances tracking performance, reduces phase delay, and improves disturbance rejection. These improvements are achieved with a controller designed to minimise computational demands in terms of memory usage and execution time.
A MediaPipe Holistic Behavior Classification Model as a Potential Model for Predicting Aggressive Behavior in Individuals with Dementia
Authors: Galanakis Ioannis , Soldatos Rigas Filippos , Karanikolas Nikitas , Voulodimos Athanasios , Voyiatzis Ioannis , Samarakou Maria
Published: November 2024

This paper introduces a classification model that detects and classifies argumentative behaviors between two individuals by utilizing a machine learning application, based on the MediaPipe Holistic model. The approach involves the distinction between two different classes based on the behavior of two individuals, argumentative and non-argumentative behaviors, corresponding to verbal argumentative behavior. By using a dataset extracted from video frames of hand gestures, body stance and facial expression, and by using their corresponding landmarks, three different classification models were trained and evaluated. The results indicate that Random Forest Classifier outperformed the other two by classifying argumentative behaviors with 68.07% accuracy and non-argumentative behaviors with 94.18% accuracy, correspondingly. Thus, there is future scope for advancing this classification model to a prediction model, with the aim of predicting aggressive behavior in patients suffering with dementia before their onset.
Redefining Women’s Bodies from the Perspective of Iranian Contemporary Female Artists
Authors: Karami Paria
Published: November 2024

In contemporary art, the representation of the “body”, particularly the female body, has emerged as a crucial site of feminist critique and exploration. This is especially evident in the works of Iranian female artists, who challenge prevailing local and global discourses surrounding female embodiment. This study examines how artists such as Shirin Neshat (b. 1957), Parastou Forouhar (b. 1962), and Shadi Ghadirian (b. 1974) use their art to redefine representations of women’s bodies within the socio-political context of post-revolutionary Iran. The restrictive post-revolutionary environment, marked by mandatory hijab laws and stringent social codes for women, has profoundly impacted artistic expression. These artists navigate this complex landscape, utilizing their work to contest both the imposed limitations and the Western gaze that often reduces Iranian women to stereotypes. By interrogating these artistic representations through a feminist lens, this paper explores the intersection of gender, politics, culture, and artistic expression, examining how these artists contribute to a broader redefinition of the female body in contemporary feminist art. This study employs a qualitative, descriptive–analytical approach grounded in feminist theory, including perspectives beyond Western thought, to analyze how these Iranian artists navigate, subvert, and reimagine traditional representations of women. By analyzing specific works, this study aims to offer a nuanced understanding of how these artists challenge both Iranian and global audiences to reconsider the boundaries of gender, identity, and power within their specific cultural and historical context.
Essential Trace Elements in the Human Metabolism
Authors: da Silva José Armando L.
Published: November 2024

A few trace elements are absolutely essential for the human metabolism, despite their low levels in the organism [...]
A Novel Quinoline Inhibitor of the Canonical NF-κB Transcription Factor Pathway
Authors: Ntavaroukas Panagiotis , Michail Konstantinos , Tsiakalidou Rafaela , Stampouloglou Eleni , Tsiggene Katerina , Komiotis Dimitrios , Georgiou Nikitas , Mavromoustakos Thomas , Manta Stella , Aje Danielle , Michael Panagiotis , Campbell Barry J. , Papoutsopoulou Stamatia
Published: November 2024

The NF-κB family of transcription factors is a master regulator of cellular responses during inflammation, and its dysregulation has been linked to chronic inflammatory diseases, such as inflammatory bowel disease. It is therefore of vital importance to design and test new effective NF-κB inhibitors that have the potential to be utilized in clinical practice. In this study, we used a commercial transgenic HeLa cell line as an NF-κB activation reporter to test a novel quinoline molecule, Q3, as a potential inhibitor of the canonical NF-κB pathway. Q3 inhibited NF-κB-induced luciferase in concentrations as low as 5 μM and did not interfere with cell survival or induced cell death. A real-time PCR analysis revealed that Q3 could inhibit the TNF-induced transcription of the luciferase gene, as well as the TNF gene, a known downstream target gene. Immunocytochemistry studies revealed that Q3 moderately interferes with TNF-induced NF-κB nuclear translocation. Moreover, docking and molecular dynamics analyses confirmed that Q3 could potentially modulate transcriptional activity by inhibiting the interaction of NF-κB and DNA. Therefore, Q3 could be potentially developed for further in vivo studies as an NF-κB inhibitor.
Genetic Insights into Congenital Cardiac Septal Defects—A Narrative Review
Authors: Cervantes-Salazar Jorge L. , Pérez-Hernández Nonanzit , Calderón-Colmenero Juan , Rodríguez-Pérez José Manuel , González-Pacheco María G. , Villamil-Castañeda Clara , Rosas-Tlaque Angel A. , Ortega-Zhindón Diego B.
Published: November 2024

Congenital heart diseases (CHDs) are a group of complex diseases characterized by structural and functional malformations during development in the human heart; they represent an important problem for public health worldwide. Within these malformations, septal defects such as ventricular (VSD) and atrial septal defects (ASD) are the most common forms of CHDs. Studies have reported that CHDs are the result of genetic and environmental factors. Here, we review and summarize the role of genetics involved in cardiogenesis and congenital cardiac septal defects. Moreover, treatment regarding these congenital cardiac septal defects is also addressed.