bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of equine corneal endothelium after exposure to 0.05% brilliant blue - an in vitro study
Authors: Andrade M.C.C. , Moreno T.M. , Muccillo M.S. , Pigatto J.A.T. , Camilo E.V.
Published: October 2019

ABSTRACT The aim of this study was to evaluate the immediate effects of 0.05% brilliant blue on corneal endothelium of horses. Thirty-eight corneas of 19 horses, male or female, of different ages were studied. Corneas were randomly divided into two groups. Group 1: Corneal endothelium was covered with 0.3mL of brilliant blue 0.05% for 60 seconds followed by rinsing with a balanced salt solution. Group 2: Corneal endothelium was covered with BSS for 60 seconds. The corneas were excised with an 8mm trephine and prepared to analyze posterior endothelial surface using a light microscope (24 corneas) and a scanning electron microscope (14 corneas). The equine posterior corneal endothelium surface observed by optical microscopy and scanning electron microscopy revealed a continuous layer of polygonal cells of uniform size and shape in both the control and treatment groups. Due to non-normal residuals at ANOVA mean comparison, a generalized linear model was utilized at 5% level of significance. The chi-square test stated that treatment and control group were not different statistically. The 0.05% brilliant blue did not cause damage to equine corneal endothelium.
Protocols for preparation of platelet rich plasma (PRP) in Quarter Horses
Authors: Miranda Stephania , Costa Maria Fernanda Mello , Rebouças Natália , Ramos Márcia T. , Lessa Daniel A.B. , Alencar Nayro X.
Published: October 2019

ABSTRACT: This study compared two protocols for preparation of platelet rich plasma (PRP) and evaluated the association between manual and automated methods for platelet count using a prospective study design. Eight clinically healthy Quarter Horses had venous blood samples collected at rest. After collection, blood samples were centrifuged twice, using two different protocols including a period of sample resting, either at the start or at the end of the protocol. Platelet counting at the start of the protocol, during, and after obtaining PRP was conducted manually or with an automated counter, followed by comparison of the two methods. In order to investigate platelet degranulation during the protocol, vascular endothelial growth factor (VEGF) was measured at each preparation stage. The protocol with sample resting before centrifugation yielded a more concentrated PRP, and the study verified that both manual and automated methods are comparable and can be used interchangeably for platelet counting. VEGF concentration did not differ significantly between protocols, or among protocol stages. The results indicate that choice of protocol for PRP preparation will affect the quantity of platelets in the final product, although platelet degranulation was not observed as evidenced by the stable VEGF concentrations measured. A larger yield of non-degranulated platelets in PRP is desirable since more α-granules will be present, therefore Protocol II is recommended. Both manual and automated counts reliably allow clinicians to obtain platelet counts and the choice of utilizing a manual or automated method is unlikely to interfere with evaluation of the final PRP product.
Diagnosis and treatment of latent tuberculosis infection in patients undergoing treatment with immunobiologic agents: a four-year experience in an endemic area
Authors: Lopes Diana Maria de Almeida , Pinheiro Valéria Goes Ferreira , Monteiro Helena Serra Azul
Published: October 2019

ABSTRACT Objective: To describe the incidence of active tuberculosis and the occurrence of adverse events after isoniazid treatment in patients with latent tuberculosis infection (LTBI) who also had chronic inflammatory diseases and were treated with immunobiologic agents in an endemic area in Brazil. Methods: The diagnosis of LTBI was based on anamnesis, clinical examination, chest X-ray, and a tuberculin skin test (TST). Patients received prophylactic treatment (isoniazid for six months) in accordance with the Brazilian guidelines. Results: A total of 101 patients were evaluated between July of 2011 and July of 2015. Of those, 55 (54.46%) were women (mean age, 53.16 ± 1.76 years) and 46 (45.54%) were men (mean age, 45.39 ± 2.13 years). A total of 79 patients (78.22%) were being treated with immunobiologic agents and 22 (21.78%) were being treated with immunomodulatory or immunosuppressive agents. In the screening for LTBI, 53 patients (52.48%) had a TST induration ≥ 10 mm. Chest X-ray findings consistent with LTBI were observed in 36 patients (35.64%). Isoniazid preventive therapy was effective in 96 (95.05%) of the 101 patients evaluated. It is of note that 84 (83.17%) of the patients experienced no adverse effects from the use of isoniazid and that 83 (98.81%) of those patients completed the prophylactic treatment (p = 0.002). Active tuberculosis was diagnosed in 5 (6.33%) of the 79 patients treated with immunobiologic agents and in 1 (4.55%) of the 22 patients treated with other immunomodulators/immunosuppressants. Conclusions: A six-month course of isoniazid proved to be safe and effective in the treatment of LTBI, which is essential to reducing the risk of developing active tuberculosis.
Use of dupilumab on the treatment of moderate-to-severe asthma: a systematic review
Authors: Bassani Cíntia , Rossi Larissa , Siveris Kaian , Sferelli Rafaella Lorenzon , Saraiva Leonardo , Tanno Luciana Kase
Published: October 2019

SUMMARY OBJECTIVE The objective of this article was to conduct a systematic review of the treatment of moderate-to-severe asthma by administrating Dupilumab. METHODS A search on the online databases EBSCO, Scielo, PubMed, Medline Bireme, Lilacs, and The New England Journal of Medicine was conducted, publications from 2010 to 2018 were selected. The inclusion criteria were articles which contained control groups, tested the validity of Dupilumab, and verified the response of patients through controlled tests. For the search of such articles, the following keywords were used: “Dupilumab”, “asthma”, “Bronchial Asthma” AND “Asthma, Bronchial” AND their correspondent in Portuguese “asma”, “Asma brônquica” and “Asma brônquica”. The exclusion criteria were literature reviews, news, articles without control groups, articles on different subjects, Dupilumab studies on other diseases, articles concerning asthma without the use of Dupilumab, and repeated articles on the databases were discarded. RESULTS The literature considers that the medication shows a good response for the treatment of moderate-to-severe asthma and assists in the improvement of lung function, aside from resulting in few side effects. It presents good efficacy, safety, and tolerance by patients. CONCLUSIONS Dupilumab is promising for the treatment of asthma, whereas conventional therapy is deemed to be insufficient. More additional studies are needed to confirm the long-term safety and effectiveness.
DEVELOPMENT AND VALIDATION OF A SMARTPHONE EDUCATIONAL GAME REGARDING HEALTHY LIFESTYLE HABITS FOR ADOLESCENTS
Authors: Moura Thais Norberta Bezerra de , Moreira Thereza Maria Magalhães , Sousa Alcilene Dalília de , Santos Neto Antonino Calisto dos , Sousa Renan Xavier e , Lima Luisa Helena de Oliveira
Published: October 2019

ABSTRACT Objective: to elaborate and validate the content and appearance of an educational game regarding healthy lifestyle habits for adolescents Method: methodological study carried, in 2016 out in Picos (Brazil). In order to develop the initial version of the game, a survey gathered scientific information and the content. In the end, the game was divided into: home screen and the living room, kitchen and the square scene, where the sports scene was inserted. To validate the instrument, 15 experts were selected, who evaluated the content, didactics and appearance of the game. Ten adolescents evaluated the appearance and usability. In addition, one questionnaire was used for the specialists and another for the adolescents. The Content Validation Index was used to validate the game, which considered the instrument and the items as validated when an index ≥ 0.78 was obtained. Results: the room scene had access to the kitchen and the square. The sport scene was designed for physical activity and the purchase of food, which would be consumed in the kitchen scene. The experts gave the game a Content Validation Index of 0.88 for the item "objectives", 0.87 for "structure and presentation" and 0.99 for "relevance", reaching a overall Content Validation Index of 0.89. For adolescents, the item "appearance" reached the index 0.97 and for the other items, 1.0 and overal index of 0.99. Conclusion: the game was validated in terms of content and appearance and could be validated clinically with adolescents as an incentive to adopt protective behaviors for their health.
CONJURAR EL ACCIDENTE DE NACER Migración, población, nacionalidad y ciudadanía
Authors: Caggiano Sergio
Published: October 2019

La atribución de nacionalidad es un dispositivo estatal clave para codificar y regular la movilidad humana. Es parte sustantiva de la producción de población (Foucault) que los Estados llevan adelante en procesos dinámicos y conflictivos, estructurados por valores de clase y género. El artículo revisa acciones de cuatro Estados en dos situaciones que involucran migrantes procedentes de Bolivia en Argentina y en España. El otorgamiento o no de nacionalidad a in- y emigrantes y a sus hijos impacta en las prácticas ciudadanas y el ejercicio de derechos de actuales y de futuros ciudadanos. Así, de cara a lo que algunos autores señalan como formas de emancipación de la ciudadanía respecto de la nacionalidad, el principal aporte del artículo es exponer, en dirección inversa, intervenciones que refuerzan este vínculo. Los datos empíricos resultan de un trabajo de campo etnográfico multisituado y de revisión de fuentes secundarias y documentos institucionales entre 2005 y 2015.
“LIBERTAÇÃO”, “CARIDADE” E O REGIME DA TROCA COM DEUS*
Authors: Garcia Ypuan
Published: October 2019

Este artigo, oriundo de trabalho de campo etnográfico realizado entre os anos de 2013 e 2016 com cristãos pertencentes a uma comunidade católica na cidade de São Paulo/SP, aborda a problemática concernente à “libertação” e à “caridade” por meio do denomino de regime da troca com Deus. Argumentarei que a consideração da caridade enquanto uma dádiva “livre” - na qual se renuncia à retribuição porque se espera uma recompensa futura que culmina na vida eterna, isto é, a libertação em termos soteriológicos – seria, no caso desses católicos, um equívoco. No regime da troca com Deus, a caridade liberta porque a libertação (e/ou liberdade) é definida como vínculo (aliança ou comunhão) com Ele, em lugar de autonomização e emancipação. Por isso, as ações caritativas localizam a presença divina no aqui e agora e são determinadas por formas específicas de retribuição a Ele.
O direito à poética na aula: sonhos de tinta
Authors: Corazza Sandra Mara
Published: October 2019

RESUMO O texto parte da docência como invenção de currículo e de didática, por meio da tradução transcriadora. Introduz a categoria do sonho para pensar uma poética de aula, constituída da necessidade dos acontecimentos. Defende o direito de sonhar com o trabalho de artistagem, feito sobre o arquivo da docência e no ato de sua escrita e leitura. Mostra que, por meio da pesquisa, nos encontros entre a imagem fantasiosa de aula e a razão, produzimos sonhos de tinta enquanto um modo factível de lidar com a urgência de forjar outra virtualidade de utopia: uma nova encenação do desejo de docência - primeiro ponto de um programa de defesa e de contra-ataque que franqueie condições para desacabrunhar a vontade de poesia. Conclui que, irreverentes e turbulentos, diante do real que nos é apresentado, talvez só assim possamos ser demiurgos: sonhar imagens de noite e fantasiar conceitos de dia, para transformar a nossa dor de professor em um adorno dourado tão delicado como a asa da cigarra.
A autonomia das universidades federais na execução das receitas próprias
Authors: Caetano Eduardo Ferreira da Silva , Campos Ivete Maria Barbosa Madeira
Published: October 2019

RESUMO O artigo teve como objetivo analisar se as Instituições Federais de Ensino Superior (IFES) exercem sua autonomia de gestão financeira assegurada na Constituição Federal de 1988, diante das diversas mudanças nas regras gerais do processo orçamentário do governo federal. Pretendeu ainda focar no quanto as universidades federais têm autonomia para executar os recursos angariados com seus esforços para financiar seu custeio e investimento. Este estudo teve como cerne a Emenda Constitucional nº 95, de 2016, e suas implicações no orçamento das IFES, na execução de fontes próprias, na redução de verbas e na sua utilização pelo Governo Michel Temer, para contingenciar recursos financeiros de custeio e das fontes próprias das IFES.
Rede Escola Pública e Universidade: produção do conhecimento para/com as lutas educacionais
Authors: Goulart Débora Cristina , Cássio Fernando L. , Ximenes Salomão Barros
Published: October 2019

RESUMO A irrupção dos secundaristas no estado de São Paulo relaciona-se a um tipo de ação coletiva que, embora recente, encontra lastro em outros movimentos de caráter antineoliberal e anticapitalista deste século, com formas de ação e dinâmicas de organização inspiradas no repertório autonomista. Há tempos um movimento social não expressava tamanho poder de mobilização, ruptura e resistência no Brasil quanto as ocupações escolares. Este artigo recupera alguns aspectos da resistência à política de reorganização escolar no estado de São Paulo, entre 2015 e 2016, e discute as estratégias de resistência surgidas das ocupações, alicerces para uma renovação das lutas por uma educação democrática no Brasil. Particularmente, tratamos da interação entre os movimentos estudantis, as universidades públicas e o sistema de justiça no contexto das ocupações escolares. Conforme dito no artigo, tal articulação constituiu um campo fértil de resistência e de solidariedade, de onde emergiu a Rede Escola Pública e Universidade (Repu). A Repu propõe o estreitamento das relações entre as universidades públicas e os movimentos de luta pela educação pública, constituindo espaço singular para a produção do conhecimento e para a ação política cujos limites e potencialidades são apresentados e discutidos.
Diagnóstico de enfermagem baixa autoestima situacional em pessoas com estomia: estudo de acurácia diagnóstica
Authors: Melo Marjorie Dantas Medeiros , Queiroz Cintia Galvão , Freitas Luana Souza , Silva Isabelle Pereira da , Xavier Suênia Silva de Mesquita , Costa Isabelle Katherinne Fernandes
Published: October 2019

RESUMO Objetivo Verificar a acurácia das características definidoras do diagnóstico de enfermagem baixa autoestima situacional em pessoas com estomia. Método Estudo transversal e descritivo desenvolvido em duas etapas. A primeira foi realizada com 90 pessoas com estomia, procedendo às análises descritivas dos dados coletados. Na segunda fase, verificou-se a inferência diagnóstica com juízes enfermeiros. Resultados A frequência do diagnóstico de enfermagem baixa autoestima situacional foi baixa (23,3%). Entre as características definidoras, prevaleceram: verbalizações autonegativas (33,3%), comportamento indeciso (28,8%) e comportamento não assertivo (26,1%). As mais sensíveis foram comportamento indeciso (71,0%) e expressões de sentimento de inutilidade (71,0%). Conclusão Observou-se que o diagnóstico de enfermagem baixa autoestima situacional pode ser identificado nas pessoas com estomia, e que há características definidoras nesse diagnóstico que melhor predizem e aumentam a chance da sua ocorrência. Nesse sentido, ressalta-se a importância da assistência de enfermagem no processo de adaptação e autoestima.
Premature Termination of a Randomized Controlled Trial on Image-Guided Stereotactic Body Radiotherapy of Metastatic Spinal Cord Compression
Authors: Suppli Morten Hiul , Munck af Rosenschold Per , Dahl Benny , Berthelsen Anne Kiil , Engelholm Svend Aage , Pappot Helle
Published: October 2019

Lessons Learned

It is possible to plan and treat some patients with stereotactic body radiotherapy (SBRT) in a timely fashion in an acute setting. Advanced and, in some indications, already implemented technologies such as SBRT are difficult to test in a randomized trial.

Background

Stereotactic body radiotherapy (SBRT) in metastatic spinal cord compression (MSCC) could be an alternative to decompressive surgery followed by fractionated radiotherapy.

Methods

In a randomized, single-institution, noninferiority trial, patients with MSCC were assigned to stereotactic body radiotherapy of 16 Gy in 1 fraction or decompression surgery followed by fractionated radiotherapy of 30 Gy in 10 fractions. Primary endpoint was ability to walk by EQ5D-5L questionnaire. Based on power calculations, 130 patients had to be included to be 89% sure that a 15% difference between the treatment arm and the experimental arm could be detected.

Results

Ten patients were accrued in 23 months, with six patients allocated to surgery and four patients to stereotactic body radiotherapy. The trial was closed prematurely because of poor accrual. One patient undergoing surgery and one patient undergoing stereotactic body radiotherapy were unable to walk at 6 weeks. Two patients were not evaluable at 6 weeks.

Conclusion

A randomized, phase II, clinical trial comparing surgery followed by fractionated radiotherapy or image-guided SBRT of MSCC was initiated. SBRT was shown to be feasible, with three out of four patients retaining walking function. The trial was determined futile as a result of low accrual.
Mechanical property modeling of aluminium nanocomposite reinforced with carbon nanotubes
Authors: Hosseyni Khorasgani Seyed Morteza , Dashtbayazi Mohammad Reza
Published: October 2019

In this study, the mechanical properties of an aluminium matrix nanocomposite reinforced with carbon nanotubes (CNTs) are modeled by using the finite-element method (FEM). The mechanical properties include the Young’s modulus, yield strength and rupture strength of the nanocomposites. The effects of the volume fraction of the CNTs, interfacial type and loading direction on the mechanical properties are studied. The FEM results for the mechanical properties of the nanocomposite are compared with the results of experimental data and the micromechanical models. The FEM predictions for the mechanical properties for different volume fractions of the CNTs provide better results than the micromechanical models. When the volume fraction of the CNTs increases from 0 to 2 vol%, the Young’s modulus, the yield strength and the rupture strength of the nanocomposite increase by 18, 18 and 29%, respectively. Due to random dispersion of the CNTs in the aluminium matrix, the mechanical properties are approximately the same in different directions. The results show that the friction interface is weaker than the adhesion interface and then the friction interface causes the mechanical properties of the nanocomposite to weaken.
Deformation behaviour and failure criteria of plastic concretes under compression stresses
Authors: Wang Siwei , Wang Wenxue , Liu Handong
Published: October 2019

Plastic concrete is a ductile building material, made of aggregate, cement, water and bentonite clay mixed at a high water/cement ratio. To explore its deformation behaviour and failure criteria, we tested plastic concrete samples under uniaxial, biaxial, conventional triaxial and true triaxial compression. The characteristics of the stress–strain and axial strain–volumetric strain curves of plastic concrete samples were investigated. There were three types of stress–strain curve: softening, plasticising and hardening. A deformation parameter was introduced to quantitatively evaluate the curve type and the steepness of the descending post-peak portion. Under multiaxial compression, the volume of the specimens decreased, reaching a minimum, then expanded. Failure occurred in the weakest lateral confinement direction. The octahedral shear strain and peak strain showed a linear relation at failure, and the correlation coefficient decreased with increasing bentonite content. The failure rule between the octahedral shear stress and normal stress is presented.
Gender mainstreaming in the Nepalese rural transport sector: working towards transformative change
Authors: Hada Jun Dongol
Published: October 2019

Nepal is progressive in mainstreaming gender equality and social inclusion in the rural transport sector. Research studies were conducted using qualitative methods to assess the extent to which people living within the zone of influence of road and bridge projects have benefitted in two rural districts, namely, Ramechhap and Okhaldhunga. The projects in these districts were successful in meeting the quantitative targets. The project's targeting approach to provide employment to women and disadvantaged groups in construction projects had very positive impacts on their livelihoods. With increased incomes, people could send their children to schools, add wealth and start small businesses. However, heavy domestic duties constrain women's potential to participate fully in road/bridge construction. (For full participation, a worker is expected to work in road/bridge construction for 90 days in a year; the wages earned would fulfil their food sufficiency for a year for an economically poor family.) Project quotas for women in user committees have increased their representation, but they are hardly influencing decisions. Participation in training is at times constrained by factors such as women's domestic duties and distance to training venues. These wider issues need more attention in accommodating the specific needs, constraints and vulnerabilities of women to bring genuine transformations in the lives of women.
Kinetic Approach to Determine 3-Amino Methyl Hexanoic Acid in Pharmaceutical Formulations
Authors: Siddiqui Farhan Ahmad , Sher Nawab , Naz Asia , Hasan Najmul , Shah Shabana Naz , Shehzad Muhamad
Published: October 2019

A simple and sensitive colorimetric spectrophotometric method based on application of chemical kinetics was produced and developed for the quantitative determination of 3-amino methyl hexanoic acid (pregabalin) in bulk and pharmaceutical preparations. Ninhydrin, a chromogenic agent was reacted with pregabalin at 70 °C and the absorbance was measured at 575 nm and kinetic correlation was evaluated between absorbance and time. The initial-rate, rate-constant and fixed-time (80 min) methods were employed for the estimation of pregabalin in the range of 10-30ug mL-1 which showed good correlation >0.9990 in all three cases with LOQ values ranging from 1.2-1.5 mL-1and LOD values ranging from 0.76-0.95 mL-1. Method validation was carried out using ICH recommendations and the variables were evaluated and optimized. The newly developed method has useful applications to determine pregabalin in pharmaceutical formulation with good recovery (98.38 to 102.12 %t) and precision (RSD < 1.4 %). Standard free energy changes and association constant were found to be 1.212 X 103 and -4.747, respectively, as determined by the Benesi-Hildebrand equation. Keywords: Colorimetric determination, pregabalin, ninhydrin, charge transfer complex.
The influence of mother-infant skin-to-skin contact on bonding and touch
Authors: Potgieter Karen Louise , Adams Fasloen
Published: October 2019

INTRODUCTION: Early skin-to-skin contact is a biological need of new born infants. Preliminary research informs us that this contact directly and indirectly influences the mother-infant relationship. This relationship in turn forms the basis of the infant's social-emotional development. This study investigated South African mother-infant dyads with varying exposure to early skin-to-skin contact and the influence on bonding and touch within the mother-infant relationship. METHOD: Contact over the first 24 hours and bonding were measured within one week postpartum. At six to eight weeks postpartum, the bonding assessment was repeated together with objective analysis of mother-infant touch during face-to-face interaction and mothers' self-reported use of affectionate touch in daily routine. FINDINGS: No correlation was found between a longer duration of skin-to-skin contact and bonding within one week postpartum. A positive correlation was identified between two hours or more of skin-to-skin contact and bonding as well as a higher rating of affectionate touch during feeding at six to eight weeks postpartum. This was substantiated by an increase in touch during face-to-face interaction. CONCLUSIONS: Early skin-to-skin contact positively influences mother-infant bonding and touch at six to eight weeks postpartum. Further more stringent research is however required to confirm these findings. Key words: Skin-to-skin contact, mother-infant relationship, bonding, maternal-infant touch, breastfeeding, affectionate touch, social emotional development
Resilience in occupational therapy students
Authors: de Witt Patricia Ann , Monareng Luther , Abraham Aaishah AH , Koor Safiyya , Saber Rizwana
Published: October 2019

At the University of the Witwatersrand, occupational therapy undergraduate students perceived their programme to be more stressful than similar health science education programmes, resulting in students experiencing mental health issues. Thus, the purpose of this study was to determine the level of resilience and stress and health behaviours of students registered in the undergraduate Occupational Therapy programme. A descriptive quantitative cross-sectional on-line survey design was used, replicating an American study of nursing students by Ahern. Permission was obtained from Ahern to use the same battery of data collection tools: demographic questionnaire, the resiliency scale; the perceived stress visual analogue scale and the health behaviours questionnaire. Once ethical clearance was obtained, the data collection battery plus an information sheet was mailed electronically to 205 students. The three questionnaires were scored as prescribed and all other data were analysed descriptively. The Kruskal-Wallis ANOVA was used to test the significant difference between the variables and Spearman's rank order correlation coefficient to determine associations between the questionnaires as well as the subtests. One hundred and seventeen questionnaires were analysed. Results indicated high stress levels within this cohort, with the major stressor being academic. Most students reported a medium level of resilience and the health behaviour questionnaire revealed a low risk. There was no significant difference between the different years and the only variables found to have a significant association was stress over the year increasing risk-taking behaviours. It was concluded that all students could benefit from some resilience training. Those who lived away from home and had poor social support were the most vulnerable. Key words: Resilience, Stress, Occupational therapy students
Introducing early active mobilisation following flexor tendon repair in the context of care in a developing country: A randomised feasibility study
Authors: Naudé Amy Buttle , de Klerk Susan
Published: October 2019

INTRODUCTION: Flexor tendon injuries remain one of the most difficult hand injuries to manage post-operatively. Early active mobilisation protocols are considered 'best practice' internationally but have not been well researched in the developing country context. The feasibility of such research, and use of these protocols, need to be determined by considering the potential for improved functional outcomes for patients, together with various contextual and resource challenges PURPOSE: To explore aspects of feasibility related to the recruitment, consent and retention rates in consideration of a future definitive Randomised Control Trail. In addition, preliminary results of an early active therapy protocol compared to an early passive therapy protocol were reported on, together with patient satisfaction and demographics METHODS: A parallel randomised pilot trial design was used. Thirty-one participants were recruited into one of two therapy groups (active or passive). Fourteen of these participants completed their therapy and eight-week assessments including: Total Active Motion, grip strength, the Michigan Hand Questionnaire and the Smith Hand Function Evaluation. 95% Confidence intervals examined feasibility data. Non-parametric data analysis was done primarily using medians and ranges RESULTS: Feasibility results of 37% recruitment rate, 97% consent rate and 45% retention rate, did not meet the criteria for success, deeming a trial in the present design, not feasible DISCUSSION: Due to the dearth of research from public health clinical settings in developing countries, this study contributes rich contextual data, but the challenges discussed need to be addressed before further research will achieve success Key words: Feasibility studies, recruitment-, consent-, and retention rates, early active rehabilitation, activity and participation
UV Crosslinking of Suspension Cells for eCLIP v1
Authors: Van Nostrand Eric , Yeo Gene
Published: October 2019

Profiling of RNA binding protein targets in vivo provides critical insights into the mechanistic roles they play in regulating RNA processing. The enhanced crosslinking and immunoprecipitation (eCLIP) methodology provides a framework for robust, reproducible identification of transcriptome-wide protein-RNA interactions, with dramatically improved efficiency over previous methods. Here we provide a step-by-step description for UV crosslinking of suspension cells to prepare them for eCLIP experiments.
KARİYER TEKERİ MODELİNE DAYALI GRUP MÜDAHALE PROGRAMININ ÜNİVERSİTE ÖĞRENCİLERİNİN KARİYER UYUMUNA ETKİSİ
Authors: Dönmezoğulları Cem , Yeşilyaprak Binnur
Published: October 2019

Bu
çalışmada kariyer tekeri modeline dayalı grup müdahalesinin üniversite
öğrencilerinin kariyer uyumuna etkisi incelenmiştir. Araştırmada deney grubu
Ankara üniversitesi Eğitim Bilimleri Fakültesi Rehberlik ve Psikolojik
Danışmanlık bölümü 4.sınıf tan gönüllü 9 öğrenci seçilerek oluşturulmuştur.
Araştırmada ön-test ve son-test, tek gruplu deneysel bir desen kullanılmıştır. Deney
grubuna 5 hafta boyunca oturumlar halinde grup müdahalesi uygulandı. Grup
uygulamasının başında ve sonunda Kariyer Geleceği Ölçeği uygulanmıştır.
Öğrencilerin kariyer uyumu öntest ve sontest puanları arasında anlamlı bir
farklılığın olup olmadığını belirlemek amacıyla Wilcoxon Testi kullanılmıştır. Araştırma
sonucunda deney grubundaki öğrencilere uygulanan kariyer tekeri modeline dayalı
kariyer uyumu programının öğrencilerin kariyer uyumunu arttırdığı görülmüştür.
Dönüştürücü Liderliğin İş Becerikliliği Üzerindeki Etkisi: Akademisyenler Üzerinde Bir Uygulama
Authors: Kerse Gökhan , Babadag Mustafa
Published: October 2019

Günümüzün
rekabet dünyasında örgütleri başarıya ulaştıracak faktörler arasında çalışanlar
önemli bir yere sahiptir. Özellikle çalışanların proaktif davranışlarının bu
konudaki katkısı yadsınamaz. Bu nedenle proaktif davranış olarak
değerlendirilen iş becerikliliği kavramı bu araştırmanın çalışma konusunu
oluşturmakta ve bu kapsamda da dönüştürücü liderliğin iş becerikliliği
üzerindeki etkisi değerlendirilmeye çalışılmaktadır. Bu değerlendirmeyi
yapabilmek için 138 akademik personelden anket yöntemi ile veri toplanmış ve
veriler istatistiki paket programları ile analiz edilmiştir. Analizler
sonucunda dönüştürücü liderliğin iş becerikliliğini pozitif yönde ve anlamlı
olarak etkilediği tespit edilmiştir. Ayrıca dönüştürücü liderliğin iş
becerikliliğinin alt boyutlarını da (görev becerikliliği, bilişsel beceriklilik
ve ilişkisel beceriklilik) pozitif yönlü ve anlamlı olarak etkilediği sonucuna
ulaşılmıştır.
Y Kuşağı Bilgi Çalışanları: Duygusal Zeka ile Örgütsel Bağlılık İlişkisi Üzerinde Öz-Yeterliliğin Rolü
Authors: Aydogmus Ceren
Published: October 2019

Bu
araştırma, Y Kuşağı bilgi çalışanlarının duygusal zekâları ile örgütsel
bağlılıkları ilişkisi üzerinde öz-yeterlilik düzeylerinin etkisini inceleyen
bir model sunmaktadır. Araştırmanın örneklemini, Ankara ilindeki üç
üniversitede yer alan tekno-parklarda bulunan 37 teknoloji şirketinde görev
yapan 591 Y Kuşağı bilgi çalışanı oluşturmaktadır. Araştırma verileri anket
tekniği kullanılarak toplanmıştır. Araştırma değişkenlerinin ölçülmesinde
Duygusal Zekâ,  Öz-yeterlilik ve Örgütsel
Bağlılık ölçekleri kullanılmıştır. Ölçeklerin geçerlilikleri doğrulayıcı faktör
analizi ile test edilmiştir. Değişkenler arasındaki ilişkiyi belirlemek için
korelasyon analizi, aracılık rolünü tespit etmek için ise yapısal eşitlik
modellemesinden yararlanılmıştır. Elde edilen bulgular Y Kuşağı bilgi
çalışanlarının duygusal zekâlarının öz-yeterlilik ve örgütsel bağlılıklarını
olumlu yönde etkilediğini göstermektedir. Y Kuşağı bilgi çalışanlarının
öz-yeterlilikleri ile örgütsel bağlılıkları arasında olumlu ve anlamlı bir
ilişki tespit edilmiştir. Sonuç olarak, Y Kuşağı bilgi çalışanlarının duygusal
zekâlarının örgütsel bağlılıkları üzerindeki etkisinde öz-yeterlilik
düzeylerinin tam aracılık etkisine sahip olduğu belirlenmiştir.
Liderlikte Ortak Vizyon Oluşturma Davranışının İşletme Performansına Etkisinde Duygusal Zekanın Düzenleyici Rolü
Authors: Koca Ballı Ayşe İpek , Kılıç Kemal Can
Published: October 2019

Çalışmanın
amacı; kadın girişimcilerin etkili liderlik davranışlarından biri olan ortak
vizyon oluşturma davranışının işletme performansına etkisinde duygusal zekanın
düzenleyici rolü olup olmadığını belirlemektir. Araştırma tanımlayıcı türde
tasarlanmış olup gerekli veriler, anket yöntemi ile toplanmıştır. Adana,
Mersin, Osmaniye ve Hatay illerinde faaliyet gösteren kadın girişimciler
çalışmanın evrenini oluşturmaktadır. Çalışma kapsamında 535 kadın girişimciye
anket uygulanmış, anket sonuçları analize tabi tutulmuştur. Araştırma
sonucunda,  ortak vizyon oluşturma
davranışının işletme performansı üzerinde pozitif bir etkiye sahip olduğu
görülmüştür. Bununla birlikte ortak vizyon oluşturma davranışı ile işletme
performansı ilişkisinde duygusal zekanın düzenleyici bir rolü olduğu tespit
edilmiştir. Böylece ortak vizyon oluşturma davranışının varlığının duygusal
zekanın daha yüksek olduğu durumlarda işletme performansına daha fazla katkı
sağladığı ortaya konmuştur.
Yoğrulmuş Killerde Dayanım ve Deformasyon Parametrelerinin Düşen Koni ve Veyn Deneyleri ile Belirlenmesi
Authors: GÜLEN Murat , KILIÇ Havvanur
Published: October 2019

Yoğrulmuş ve örselenmemiş killi zeminlerin drenajsız kayma mukavemeti pratik olarak veyn deneyi ile belirlenebilmektedir. Diğer bir pratik deney olan düşen koni deneyi ile de yoğrulmuş kohezyonlu zeminlerin drenajsız kayma mukavemetine geçiş yapılabilmektedir. Ancak bu geçiş sırasında bir düşen koni faktörüne (K) ihtiyaç duyulmaktadır. Deneysel verilerle kalibre edilen koni faktörü, farklı su muhtevaları için hesaplanan drenajsız kayma mukavemetleri ve kritik durumdaki boşluk oranları kullanılarak drenajlı kayma mukavemeti açısına geçiş yapılmaktadır. Bu çalışmada, yoğrularak hazırlanan farklı endeks özelliklere sahip kohezyonlu zemin örnekleri üzerinde, literatürde önerilen yöntemlerden faydalanılarak sıkışabilirlik ve mukavemet parametreleri pratik olarak belirlenmiştir. Aynı zeminler için ödometre ve üç eksenli basınç deneylerinden ile elde edilen sıkışabilirlik ve mukavemet parametreleri ile karşılaştırılarak uygulanan yöntemin kullanılabilirliği değerlendirilmiştir.
AXIOLOGICAL ASPECT OF STUDENT PROFESSIONAL TRAINING: MATCHING DEMAND AND OFFERS OF LABOR MARKET
Authors: N. Ganieva Yoldyz , V. Kiryakova Aida , Gladkikh G. , V. Lopanova Elena , N. Sazonova Anzhelika , V. Mitina Galina , B. Shirokikh Oksana
Published: October 2019

The purpose of the article: The Relevance of the study is determined by modern trends in the development of the labor market, based on demand and supply of goods - a graduate of the University. At the same time, student’s professional training in the educational process of the University is traditionally carried out based on the basic values of the specialist's individual, due to the need for them, and the demand and supply of the labor market are determined by the demand for a specialist as an intellectual resource of production.

Materials and methods: The methodology of this study is based on the innovative content of professional training of a University student, focused on the needs of a specialist in professional self-affirmation as a personal and social value corresponding to the demand and supply of the labor market, presented in the concept of cultural competency-based approach to training, in the theory of changes in the labor market, in projects of future changes in the labor market, where demand and supply for the training of a modern competent specialist are used as driving forces.

Results of the research: the algorithm of designing cognitive, motivational, behavioral, emotional components of the values of the student’s professional training is justified and their compliance with the demand and supply of the labor market is proved. Knowledge about the value aspects of a University student’s professional training, about the features of their compliance with the labor market’s demand and supply, will help to avoid, localize or eliminate problems in the real educational process.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of an axiological aspect of student professional training: matching demand and offers of labor market is presented in a comprehensive and complete manner.
DIFFERENTIATED APPROACH PROBLEMS TO INNOVATIVE DEVELOPMENT MANAGEMENT IN RUSSIAN REGIONS
Authors: V. Rajskaya Marina , A. Sagdeeva Anzhella , A. Gusarova Irina , V. Panteleeva Yuliya , V. Malysheva Tatyana , G. Ershova Irina
Published: October 2019

The purpose of the article The purpose of the study is to determine the features of factors’ development and systematization affecting the degree of innovation activity and efficiency of projects in the Russian regions.

Materials and methods: The main research methods used in the article are the method of description, which allowed determining of the level and trends of Russian regions’ innovative development; the method of cluster analysis for regions’ classification by innovative activity’s parameters in order to identify the characteristics and determine the directions of the target differentiated approach to the development of innovation.

Results of the research: The article presents the analysis of innovative development dynamics of the Russian regions’ industrial sector; the tendencies of scientific and innovative activity’s financing in the Federal districts; the regions’ classification by the parameters of innovative activity in order to identify the characteristics of innovations’ development and commercialization.

Applications: This research can be used for universities, teachers, and students.

Novelty/Originality: In this research, the model of differentiated approach problems to innovative development management in Russian regions is presented in a comprehensive and complete manner.
Las exportaciones de plátano como una estrategia de desarrollo rural en Colombia
Authors: Carvajal-García Marcela , Zuluaga-Arango Paula , Ocampo-López Olga Lucía , Duque-Gómez Daniela
Published: October 2019

Este artículo busca identificar oportunidades en mercados internacionales para el plátano fresco y transformado de origen colombiano, a partir del análisis de información obtenida de fuentes secundarias en el que son analizadas las variables de tendencias de consumo, estadísticas de producción, exportación e importación, normativa, restricciones y requisitos técnicos, para el periodo 2013-2017, a las cuales son aplicados los criterios de clasificación de los modelos Uppsala y Vernon. Se identifican los productos con mayor demanda y los países con superior probabilidad de acceso, como propuesta para su incorporación en la estrategia competitiva para los productores y transformadores de plátano en Colombia. El estudio concluye que el producto en fresco presenta una demanda significativa, al igual que productos transformados como plátano congelado, chips y harina de plátano, que pueden ser comercializados con mejores resultados en el mercado norteamericano y europeo.
Las zonas francas en Colombia: desarrollo empresarial y regional 2009 - 2016
Authors: Arévalo-Luna Guillermo Alexander , Arevalo-Lizarazo Guillermo Alejandro
Published: October 2019

Las zonas francas son un instrumento de política comercial que genera empleo, inversión y exportaciones, gracias a incentivos tributarios que reciben las empresas localizadas en su interior. El objetivo del artículo es examinar hasta qué grado en el periodo 2009-2016 la política de zonas francas contribuyó a concentrar los factores de producción y polarizar el crecimiento en las regiones centrales al tiempo que aumentó la disparidad regional, dadas las diversas limitaciones de carácter geográfico y de dotación factorial en las distintas regiones del país. El estudio utiliza el método analítico-descriptivo de fuentes estadísticas públicas y privadas. La hipótesis propuesta es la siguiente: aunque las zonas francas contribuyen a generar empleo, atraer inversión y aumentar las exportaciones, también fomentan el aumento de la disparidad regional. El estudio concluye que las políticas públicas estatales complementarias a la de zonas francas deberán contribuir a atenuar las desigualdades territoriales en favor de las regiones periféricas con mayor atraso relativo.
Cartografía y Nación en América Latina (siglos XIX y XX): una aproximación a los casos de Argentina, México y Colombia.
Authors: Delgado Juan David , Osorio Merchán Yelitza
Published: October 2019

El presente artículo tiene por objetivo aproximarse a la manera en cómo la geografía y la historia han abordado la relación entre producción cartográfica y formación del Estado-nación en Argentina, México y Colombia durante el siglo XIX y parte del XX. Por medio de una revisión de algunos autores sobre el tema, se pretende mostrar la existencia de una transformación en la manera de abordar la historia de la cartografía en América Latina. Dicho cambio, se manifiesta en el hecho de considerar el mapa como algo que no solo se refiere al estado de la técnica en un periodo específico, vinculándolo al mundo de la representación y de las relaciones de poder, como instrumento clave en la consolidación geopolítica de los estados-nacionales latinoamericanos. Se busca además evidenciar algunas líneas de trabajo común, así como identificar temas específicos según país.
Cartografía Social como recurso metodológico para el análisis patrimonial. Experiencias de mapeo en Miramar (Córdoba, Argentina)
Authors: Martin Silva Valeria Belén , Zabala Mariela Eleonora , Fabra Mariana
Published: October 2019

Se presenta una reflexión en torno a la Cartografía Social como propuesta teórica-metodológica participativa de investigación para el estudio, valoración y gestión integral del patrimonio arqueológico, partiendo de una experiencia de trabajo de campo en la localidad de Miramar de Ansenuza (Córdoba, Argentina). En el mismo aplicamos la técnica del mapeo colectivo, estableciendo un diálogo entre trabajadores del museo, vecinos, turistas e investigadores sobre patrimonio, desde una perspectiva colaborativa y transdisciplinaria, para analizar las oportunidades y desafíos que nos ofrece la Cartografía Social para el abordaje de las relaciones entre comunidades sobre patrimonio y el territorio. Se concluye que a partir de las prácticas cartográficas críticas y participativas realizadas se fueron abriendo camino nuevas formas de entender el espacio habitado que priman el sentir de la comunidad local en la construcción del paisaje cultural local. En este sentido, se busca aportar nuevas estrategias metodológicas para la investigación patrimonial.
El territorio habitado. Parkour, motricidades y afectos en la ciudad de Quito
Authors: Vásconez Vaca Dennis Javier
Published: October 2019

El presente artículo es una reflexión sobre movimiento corporal y afectividades en la ciudad de Quito, a través de una observación profunda y una larga reflexión sobre estos temas desde la óptica del parkour, práctica motriz dedicada a recorrer los espacios urbanos de la forma más fluida y eficaz posible por medio únicamente del cuerpo. A través de la experiencia de aprendizaje y práctica del parkour, entre las actividades del colectivo Étre Fort, este estudio indaga en las transformaciones que conlleva el ejercicio de esta disciplina sobre la ciudad, su producción espacial y su territorio habitado, a la vez que reflexiona sobre los elementos afectivos que surgen en dicha práctica y su papel en estas transformaciones.
Lo urbano y los espacios vacíos en la Amazonia como elementos en la producción de cartografías nacionales de Colombia
Authors: Aponte Jorge
Published: October 2019

Las representaciones que tradicionalmente tenemos de la Amazonia omiten o minimizan los fenómenos urbanos que han sido parte fundamental de su configuración territorial, dejándonos la imagen de “espacios vacíos”, “incógnitos” o “salvajes”, que encierran selvas exuberantes, ampliamente diversas en fauna y flora, pero que no tienen dueños o habitantes civilizados y, por lo tanto, sus riquezas pueden ser aprovechadas por quienes describen el territorio. Sin embargo, esos mismos espacios se encuentran internamente demarcados por poblaciones que por lo menos en la representación cartográfica ponen en cuestión el discurso del vacío, lo cual evidencia que la construcción de dichos vacíos se encuentra enmarcada en disputas por el control territorial en las cuales borrar o no representar formas humanas de habitación, así como establecer enclaves urbanos, bien sea en la práctica o solo en la representación, resulta funcional para el ejercicio de apropiación territorial. En este sentido, como parte del inicio exploratorio de esta investigación, reflexionaré sobre el papel de la ciudad en la producción espacial amazónica y las formas como lo urbano ha sido representado en el marco de las disputas asociadas a la consolidación de los espacios territoriales Estado-nacionales en la Amazonia, enfatizando particularmente en los ejercicios simbólicos de representar a Colombia en la Amazonia. Para ello, trabajaremos a partir del análisis y la deconstrucción del mapa, siguiendo la propuesta metodológica de Bryan Harley (2005), e intentaremos comprender los sentidos y razones de la representación iconográfica de lo urbano en algunos mapas que incluyen la región amazónica a finales del siglo XIX.
Produção de mudas de alface sob diferentes substratos e proporções de casca de arroz carbonizada
Authors: Freitas Gilson Araújo de , Barros Hélio Bandeira , Dos Santos Manoel Mota , Do Nascimento Ildon Rodrigues , Costa Jefferson da Luz , Da Silva Rubens Ribeiro
Published: October 2019

O sucesso na produção de alface é iniciado pela obtenção de mudas de boa qualidade, pois se mal formadas darão origem a plantas com produção abaixo de seu potencial genético. Assim, objetivou-se avaliar a produção de mudas de alface sob diferentes substratos e proporções de casca de arroz carbonizada. O delineamento experimental foi inteiramente casualizado, com quatro repetições. Os tratamentos foram dispostos em esquema fatorial 4x5, sendo quatro tipos de substratos (PlantHort I, PlantHort II, PlantHort IIIe substrato comercial Plantmax®) e cinco níveis palha de arroz carbonizada (0, 25, 50, 75, 100%). As características orfofisiológicas avaliadas foram teor de clorofila a e b, área foliar, área foliar específica, razão da área foliar, razão da massa foliar, caulinar e radicular aos 24 dias após a semeadura. A adição de proporção crescente de casca de arroz carbonizada promove redução nas características morfofisiológicas das mudas de alface. Independente da proporção de casca, os substratos PlantHort I, PlantHort II e PlantHort III, promovem maior produção e distribuição equilibrada de fotoassimilados na parte aérea/raiz, em comparação ao substrato Plantmax®, que ssegura nessa condição apenas o crescimento do sistema radicular em detrimento do aéreo. Os substratos alternativos proporcionam produção de mudas de alface de melhor qualidade em detrimento do substrato comercial Plantmax®.