bluuebunny/crossref_metadata_2025 huggingface dataset:
Heterologous expression of Bacillus subtilis SL-44 glycosyltransferase catalyzed synthesis of ginsenoside Rh2
Authors: Zhang Yufei , Liu Xiaochen , Li Zhiyan , Yue Junsong , Pan Hong
Published: September 2023

In this paper, the synthesis of ginsenoside Rh2 was catalyzed by using heterologous expression of Bacillus subtilis SL-44 glycosyltransferase. The synthesis parameters of ginsenoside Rh2 were optimized by the selection of strains and chemical supplies, the establishment of kinetic equations for the respiration rate of UGT enzyme, the effect of storage temperature on the model, and the glycosylation reaction of ginsenoside PPD with UGT. The effect of Rh2 saturation on the thermal denaturation temperature of the protein was analyzed along with the kinetic properties of the enzyme GE02773 (GE03484) while varying the saturation of Rh2. The results showed that the conversion of ginsenoside Rh2 reached 84% at a temperature of 35℃, pH 8, 5% DMSO, 0.4 of M-UDPG, and 1M-PPD in reaction with GE02773. In this paper, we successfully achieved the efficient synthesis of ginsenoside Rh2, which provides new ways and ideas for the application and synthesis of ginsenoside Rh2, with important practical significance and scientific value.
The development of online and offline integration teaching of mental health education for college students based on sequential quadratic programming algorithm
Authors: Peng Juan , Gao Changfeng , Xia Jing , Li Xiaojun
Published: September 2023

This paper firstly focuses on the automatic detection of mental health in colleges and universities and the sequential quadratic programming algorithm, proposes a psychological abnormality detection model for college students based on the sequential quadratic programming algorithm, and in the feature vectorization process, uses constraint functions and coefficient matrices to process various types of features into vector sequences of length k weeks to help quantify the trajectory of students’ school activities, and trains and establishes a student psychological abnormality detection model. Then, on the technical basis of the psychological abnormality detection model, the mental health education system is constructed, the online and offline integration teaching development is realized through the teaching system, and the performance of the education system is verified. The results show that the average score of the traditional psychological teaching model 1-10 week test is 76.52, compared to the average score of 78.51 in the mental health education system teaching 1-10 test, with an error value of 1.89. This study uses the mental health teaching system to retrieve information on students with current mental health problems at any time, and there this is to realize dynamic online and offline coeducation.
Research on the scene design of virtual reality technology in film and television animation
Authors: Hu Qiaohong
Published: September 2023

In this paper, firstly, we study the modeling of film and television animation based on virtual reality technology and use quadratic polynomial inverse to control the intensity of light source to establish the lighting model. The image alignment is designed for the scene based on multi-resolution decomposition, and the filtered image layer is obtained by calculating the difference between two layers of Gaussian filtered images, and the Laplace pyramid is established to match the image resolution consistently. Then the scene is chunked and locally rendered, and a smooth transition between geometry and texture is achieved by morphing the geometry next to the texture. Finally, the scene effect, LOD detail level and interactive experience effect before and after simplification are compared and analyzed. The scene design of virtual reality technology basically scores 5-6 on each index, while the scene design of common technology only scores 3-4, indicating that the scene design of virtual reality technology works well.
Corpus Analysis as a Means of Meaning Disambiguation: Collocational Analysis of Near-Synonyms of the Verb ‘Destroy’
Authors: Ivanova S. V. , Medvedeva S. N.
Published: September 2023

The current paper is aimed at corpus-based differentiation of near-synonymous lexemes with the meaning ‘to destroy’. The research implies a series of consecutive steps: to discuss synonymy-related problems in modern linguistics; to compile a list of near-synonymous lexemes with the meaning ‘to destroy’ by means of Corpus of Contemporary American English (COCA); to analyze and compare definitions of the chosen verbs in Merriam-Webster Dictionary (MWD); to generate lists of right-context collocates for each of the verbs in COCA; to put the collocates into semantic clusters and compare the obtained clusters. The list of lexemes under study contains such verbs as ‘destroy’, ‘ruin’, ‘break’, ‘obliterate’, ‘raze’, ‘annihilate’, ‘crush’, ‘devastate’, ‘wreck’, and ‘demolish’. As a result, semantic clusterisation of the right-context collocates helped establish that all verbs of the group collocate with the lexemes representing values and threats where destroying values evokes negative feelings and associations while destroying threats is perceived as a positive action. The verb ‘ruin’ is typically used with the clusters ‘meals and food’, ‘holidays’, ‘leisure activities’, ‘entertainment’ and ‘human relations’, meaning deprivation of enjoyment and happiness. The verb ‘break’ has a wide array of collocates resulting in a variety of conventionalized expressions. The results of the corpus-based research of lexical semantics may be helpful to those professionally engaged in second language teaching as well as in translation and lexicographic practice.
Journalism’s Power of Discourse: Be it Through A Periscope or Kaleidoscope
Authors: Roozafzai Z. S.
Published: September 2023

The present research paper delves into the power of journalism’s discourse through a comparative analysis of literary and non-literary journalism. Drawing on the metaphorical imagery of periscopes and kaleidoscopes, the study aims to explore how journalism’s discourse shapes readers’ perceptions and interpretations of events, blurring the line between reality and fiction. The paper adopts a qualitative research approach with a phenomenological design. Through in-depth analysis and interpretation, the study examines the power of fictional and non-fictional journalism, drawing upon the concept of metaphor to describe how the discourse of journalism operates. The research questions are explored within the frameworks of Post-Truth, Linguistic Relativism, and Transcendentalism to gain a comprehensive understanding of the power inherent in these two genres of journalism. The empirical material for this research comprises a wide range of literary and non-literary journalistic texts, including articles, news reports, and narrative journalism pieces. Additionally, scholarly works discussing the impact of journalism’s discourse on readers’ perceptions are included to provide a holistic view of the subject. The study reveals that journalism’s discourse, whether in literary or non-literary form, holds a double-edged power over readers’ minds. Utilizing the metaphorical comparison of periscopes and kaleidoscopes, the research highlights the relative and manipulative nature of journalistic language. Moreover, the power of literary journalism, bolstered by imaginative and creative writing techniques, exerts a profound influence on shaping readers’ worldviews. The research emphasizes the significance of understanding journalism’s power in shaping public opinion and perception. While acknowledging the complexity and nuance of this phenomenon, the study underscores the need for continued research to gain further insight into the workings of journalism’s discourse in a rapidly evolving media landscape.
Bloggers’ Speech Behavior: Analysis and Diagnosis of Personal Traits from the Perspective of Implicit and Functional Pragmalinguistics
Authors: Zaslavnov D. A. , Matveeva G. G.
Published: September 2023

The aim of this paper is to present a comprehensive methodology for conducting both traditional and modified content analysis using transcripts of spoken language from video bloggers as source material. The specific focus of this research centers around video content dedicated to reviewing retro automotive vehicles. The authors delve into two fundamental branches of pragmalinguistics, namely the implicit and functional aspects, while also detailing the analytical techniques employed within these paradigms. The practical application of these methods is illustrated using the oral speeches of the blogger Alexander Chikunov as a case study, providing a clear and tangible demonstration of the process for diagnosing individual personality traits. The initial phase involves an analysis of the material through the lens of implicit pragmalinguistics, encompassing the frequency analysis of speech patterns within the context of selected linguistic strategies, coupled with rigorous statistical data processing. The outcomes pertaining to a specific blogger are subsequently juxtaposed against data from other bloggers within the same genre, thereby facilitating the identification of shared, stereotypical, and unique personality characteristics attributed to the blogger. Moving forward, this article highlights individual traits of the blogger, which were discerned through traditional content analysis techniques. Finally, the study involves an insightful interpretation of the acquired data, culminating in the development of a nuanced portrait of Alexander Chikunov’s speech behavior. A notable aspect of this research lies in its pioneering effort to discern and systematize linguistic features exclusively found within the domain of video blogs. This is achieved by utilizing unscripted spoken language from bloggers as empirical evidence, adding a distinctive dimension to the study’s scientific novelty.
Exploring the Functional and Semantic Fields of ‘Heaven’ and ‘Hell’ Conceptual Metaphors in Media News Headlines
Authors: Filyasova Yu. A.
Published: September 2023

The research aims to conduct a functional analysis of the opposing conceptual metaphors ‘heaven’ and ‘hell’ within English headlines from BBC and The Guardian news between 1999 and 2023. The relevance of this study lies in the need to explore the lexical meaning of fundamental theological terms based on the unreal cognitive constructs in the context of evolving social paradigms. Various research methods were employed, including continuous sampling, classification, thematic analysis, definition analysis, and semantic analysis.

The findings indicate that the conceptual metaphor ‘hell’ possesses a broader semantic field compared to ‘heaven,’ both in terms of definition and function. Metaphorical usage is prevalent, but headlines also feature ‘heaven’ and ‘hell’ within idiomatic, emphatic, allusive, direct, zeugmatic phrases, and contaminations. These metaphors encompass thematic areas with polar connotational meanings:

Hell: Politics (political instability, struggle, political figure replacement, anti-crisis measures), Social life (reforms, discrimination, limitations, mandatory expenses), Crimes (abuses, threats, harassment, assaults, victims), Nature (natural disasters, difficult conditions, environmental catastrophes), Sport (injuries, competition, psychological attacks, overcoming), Entertainment (poor quality service, bad habits, imbalance, disruptions), Travel (unforeseen circumstances, transport collapses), Culture (culture shock).

Heaven: Politics (political decisions, electoral victories), Social life (festivals, feasts, family relations, relationships between generations), Crimes (controversy resolution, search for solutions), Nature (biodiversity, renewal of nature), Sport (victories, lucrative contracts, goal achievement), Entertainment (parties, bright performances, romanticism), Travel (pleasure, rest, nature), Culture (acquaintance with outstanding cultural objects, visiting cultural events).

This research demonstrates that the dichotomous representation of the conceptual metaphors ‘heaven’ and ‘hell’ is marked by polyfunctionality, driven by the universal evaluative component inherent in their meaning, rooted in the implied polarization of the concepts ‘good’ and ‘bad.’ The emotional and moral dimensions contribute to heightened news perception and effective communication within media discourse.
Технические измерения в сварочном и аддитивном производстве
Authors: Стаценко В. Н. , Погодаев А. В.
Published: September 2023

В пособии приведены материалы для проведения лекционных занятий и самостоятельной работы по дисциплине «Технические измерения в сварочном и аддитивном производстве». Включает краткие сведения о стандартизации в области машиностроения, системах классификации и кодирования изделий, системах и видах межотраслевых стандартов, показателей квалиметрии. В разделе метрологических измерений приведены сведения о видах единиц измерения, их эталонах, методах прямых и косвенных измерений, видах их погрешностей, видах средств измерений и их метрологических характеристиках. В разделе основ технических измерений представлены данные по методам и характеристикам измерений основных физических величин, используемых в инженерной практике в области машиностроения. Ключевые слова: стандартизация, кодирование, стандарты, квалиметрия, эталоны, единицы измерений, погрешности, методы, характеристики, физические величины, отсчетные устройства.
Технологические особенности специальных методов сварки
Authors: Стаценко В.Н. , Подберезных А.А. , Малютина В.А.
Published: September 2023

В пособии приведены материалы для проведения лекционных занятий и самостоятельной работы по дисциплине «Специальные методы сварки», изучение которой предусмотрено рабо-чим учебным планом. Включает краткие сведения о методах нетрадиционных способов сварки, а также материалы по технологическим особенностям этих методов сварки для различных конструкций. Предназначено для бакалавров направления подготовки 15.03.01 «Машиностроение». Ключевые слова: холодная, ультразвуковая, взрывом, диффузионная, трением, высокочастотная, термитная сварка, технология особенности.
The effect of weight loss and dietary habits on glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia: a cross-sectional study
Authors: Al-Saeed Abdulghani , Mohamed Nawaf , Al-Sarari Abdulrahman , Osman Huda , Aljeaid Raghad , Al-hissi Shuruq , Hussamuldin Abdulrahman , Al-Qumaizi Reyof , Alzahrani Yara
Published: September 2023

Background: Type 2 diabetes mellitus (T2DM) is a prevalent chronic metabolic disorder associated with substantial mortality and morbidity rates. This study, conducted across various regions of Saudi Arabia (SA), aimed to assess the impact of weight loss and dietary practices on glycemic control among adult individuals with T2DM.
Methods: A cross-sectional study involving 600 adult residents diagnosed with T2DM was carried out through an online questionnaire. Exclusions were made for individuals with type 1 diabetes, those in pregnancy, and those under 18 years old. Data analysis was conducted using the Statistical Package for the Social Sciences, with a significance level set at p ≤ 0.05.
Results: The study cohort comprised 50.2% males, with 32.2% aged 51 years and older, and 42.0% falling into the overweight category. Our findings revealed statistically significant relationships between adhering to a dietary plan and its impact on blood glucose levels (p = 0.001), as well as between dietary habits and blood glucose control (p = 0.047). Furthermore, significant associations were observed between dietary knowledge and skills and blood glucose control (p = 0.001), body mass index (BMI) and blood glucose control (p = 0.001), and weight changes attributed to the current diet and blood glucose control (p = 0.004).
Conclusion: In conclusion, this study underscores the importance of dietary adherence, knowledge, and skills in managing T2DM. Notably, our findings emphasize the significant relationships between following a dietary plan, addressing eating problems, acquiring dietary knowledge and skills, managing BMI, and adapting to weight changes within the context of the current diet, all of which play a pivotal role in achieving optimal glycemic control among adults with T2DM in SA.
Structural Properties of Liquid CaO–SiO2–P2O5 System
Authors: Anh Nguyen Mai , Van Hong Nguyen
Published: September 2023

Crystalline structure of CaO-P2O5-SiO2 system at 3,000 K were investigated by molecular dynamic simulation. The models with different concentrations of P2O5 (5-40 mol%) were constructed by using Born-Mayer-Huggins potentials. The size of models was from 5,270-5,520 atoms. The local environment of elements and glassy-network structure were investigated in detail. The radial distribution functions (RDFs) showed that the average first nearest neighbor distances for Ca-O, P-O and Si-O were of 2.28-2.3Å, 1.56-1.58Å and 1.64-1.68Å, respectively. The BO fraction increases and NBO ratio decreases with the uptrend of the concentration of P2O5. The change of P2O5 content also changes the structures of [SiO4] and [PO4] tetrahedrons clusters.
The Evident of Coupled Spin and Electron-phonon Interactions in Cd2Os2O7 Pyrochlore
Authors: Huy Le Duc , Nghia Nguyen Xuan , Huyen Nguyen Thi , Thi Kim Oanh Vu , Van Minh Nguyen , Thi Minh Hien Nguyen
Published: September 2023

We present the results of the temperature dependence of the Raman spectra of pyrochlore Cd2Os2O7 single crystal in a temperature range of 100-270 K. We found that, among the six observed Raman active modes, the 762 cm-1 phonon has a significant peak shift and asymmetric Fano lineshape. The temperature-dependent of the frequency and full width at half maximum (FWHM) of the phonon shows the kinks near the Néel temperature. The complex temperature-dependent asymmetry Fano parameter and the anomalies of the FWHM below Néel temperature indicate coupling of the 762 cm-1 phonon to both electron and spin degrees of freedom. In addition, we found the Fano asymmetry rapidly drops below the Néel temperature towards its minimum value of ~ 200 K. Thus, at temperature ranging from 200 K to TN, the pyrochlore is suggested to be in an all-in -all-out ordered semimetallic state. We also confirm that Raman scattering temperature dependence provides a simple and powerful method for investigating temperature transitions and coupling in pyrochlore materials.
Thermoelectric Performance of Bi1.8Sb0.2Te3.0 Alloys under High Pressures
Authors: Thi Kim Anh Do
Published: September 2023

The pressure eﬀect on the thermopower has been investigated for the Bi1.8Sb0.2Te3.0  alloys. We have found an anisotropic pressure dependence on the thermopower for p- and n-type Bi1.8Sb0.2Te3.0 at room temperature. Along a-axis, for p-type, the thermopower value increased with increase of pressure at a rate of 13.9 %/Gpa, whereas, along c-axis, itkeeps approximately constant.. The absolue value of the thermopower decreased with pressure along both a- and c-axis for n-type. The power factor increased largely with increase of pressure for p-type Bi1.8Sb0.2Te3.0, while it is approximately constant for n-type.
Reconfigurable Generation of PAM-4 Signal Based on Fano Effect for Optical Interconnect Systems
Authors: The Duong Do , Duy Tien Le , Thi Hong Loan Nguyen , Thanh Nhat Hoang , Trung Thanh Le
Published: September 2023

We present a novel low-power architecture for the generation of multilevel pulse amplitude modulation (PAM-4) signal generation.  A new structure of a micro-ring resonator based on a 4´4 MMI (Multimode interference) coupler is proposed to control the coupling coefficient and Fano shapes. Based on this structure, a high linearity of the transmission is created, compared with the Mach Zehnder Interferometer (MZI) conventional structure. Here, instead of using directional couplers and MZI as shown in the previous reports, in our method only two 4´4 multimode interference structures on silicon on insulator (SOI) waveguides has been used. The new design is compatible and suitable for the current CMOS fabrication technology. In this work, the special design is as follows: one of two MMI couplers is used to be a micro-ring resonator and two segmented phase shifters are used in the micro-ring resonator to generate 4 levels of the PAM-4 signal. The micro-ring resonator is controlled to work at the over-coupled region, so the Fano effect can be generated. This proposed PAM-4 architecture uses the generated Fano effect, therefore an extreme reduction in power consumption can be achieved. A large fabrication tolerance of ±500 nm and a compact footprint of 10´500 µm2 can be carried-out. The device is simulated and optimally designed using the FDTD (finite difference time domain) and EME (Eigenmode Expansion). This architecture can be useful for optical interconnects and data center network applications.
Influence of Calcium on the Structure and Hydrophilic of CaTiO3 Coating on Titanium Implants
Authors: Thanh Tuyen Nguyen Thi , Trung Kien Nguyen Duc , Viet Nguyen Xuan , Thuy Linh Lo Thi , Ngoc Huyen Tran Thi , Mai Anh Nguyen Thi , Lam Nguyen Van , Phong Truong Quoc , Dung Mai Xuan , Bach Dao Hong , Minh Dang Nhat , Wang James , Vuong Pham Hung
Published: September 2023

Calcium titanate (CaTiO3), a multi-metal oxide has received extensive attention in recent years, due to its unique structural features, high chemical stability, strong catalytic activity, inexpensiveness, low toxicity, and easy synthesis. In this work, we have focused our research on and investigated the influence of Ca weight on the microstructure and properties of CaTiO3 films. CaTiO3 films on TiO2 nanotube templates were synthesized using hydrothermal method at 200 oC for 24 h. The TiO2 template was synthesized by anodizing using a Ti plate. The synthesized materials were analyzed on their crystal phase, surface morphology, Raman characterization, surface roughness, and hydrophilic properties by X-ray diffraction (XRD), Raman, scanning electron microscopy (SEM), 3D optical Profilometer, and contact angle measurement. The synthesized film exhibited a morphological transformation from nanotube morphology to nanopillars. Notably, the hydrophilic properties and the surface roughness of the CaTiO3 films were altered after hydrothermal treatment of the TiO2 nanotube template. These findings could potentially lead to the development of highly efficient materials for use in biomedical implants.
Incidence Rateand Risk Factors of Central Line-Associated Bloodstream Infection
Authors: Thi Huong Hao Duong , Minh Dien Tran , Thi Ha Le , Viet Tung Cao
Published: September 2023

Objective: Determination of incidence rates and some risk factors for Central Line-Associated Bloodstream Infection (CLABSI) at the Neonatal Center of Vietnam National Children's Hospital. Methods: 416 neonates who were inserted central line from 01/01/2021 to 30/06/2022 were enrolled in our study. CLABSI was defined as CDC 2017 criteria (LCBI3). The primary factors included obstetric history, perinatal history, characteristics of catheters, duration of catheter placement, etc. Result: A total of 672 central lines were placed in 416 infants. Of these, 32 CLABSI cases were identified. Rates of CLABSI was 5.7 infections per 1000 catheter days. Predisposing factors included duration of catheter placement of more than 28 days (OR = 2.9; 95% CI: 1.03 – 8), abdominal condition (OR = 5.3; 95% CI: 1.5 – 18.6) and steroid used (OR 5.3; CI 1.98 – 14.3). Conclusion: The “CLABSI prevention package” was effective in reducing the CLABSI rate and could be applied in other hospitals.
Applications of Platelet-rich Plasma in the Treatment of Musculoskeletal Injuries
Authors: Thi Thanh Pham , Thi Mai Nguyen , Thi Ngoc Ha Nguyen , Thi Hien Mai , Dac Tu Nguyen
Published: September 2023

The use of platelet-rich plasma (PRP), which has the ability to hasten the repair of soft tissue, cartilage, and bone, has revolutionized musculoskeletal medicine. Applications include treatment of osteoarthritis, tendinopathy, chondropathy, acute and chronic soft tissue injuries, muscle or ligament tears, as well as enhancement of healing of cartilage joints. With the ability to promote safe and natural healing, PRP is considered a promising alternative to surgery. Recently, there is an emerging literature on the beneficial effects of PRP for chronic non-healing tendon injuries and cartilage degeneration. This review article provides an overview of recent basic science and clinical studies on the applications of PRP to the treatment of musculoskeletal injuries.
Current Situation and Factors Related to Stress, Anxiety, and Depression of Pharmaceutical Personnel at Some District Public Health Facilities in Can Tho City, Vietnam in 2021-2022
Authors: Hung Nguyen Phuc , Dieu Phap Le , Yen Phung Phi , Phong Cao Huynh , Huong Vo Thi My
Published: September 2023

During the COVID-19 pandemic, there were numerous studies conducted around the world on stress, depression, and anxiety in medical personnel. However, the research on pharmaceutical staff, who are also a significant contributing force in prevention at the hospital, is still limited. The study was carried out by a cross-sectional descriptive method. A total of 125 pharmacy staff working at the medical facilities were directly interviewed. The χ2 test was used to test the relationship between factors with α = 0.05, and the odds ratio (OR) with a 95% confidence interval was calculated. The obtained results showed that the percentages of stress, anxiety, and depression among pharmacy staff were 67.2%, 12.0%, and 10.4%, accordingly. Situational stress, anxiety, and depression correlated to education levels, monthly income, and weekly working time. This research emphasized the importance of mental health care for health workers. It promoted the state management agency to organize training courses and share soft skills with pharmaceutical staff to overcome difficulties and bad psychology while on duty at the department.
Effects of Citric Acid and Sodium Alginate on the Stability and Dissolution of Clarithromycin Extended-Release Tablet
Authors: Bao Ngoc Tran , Ha Phuong Do , Thi Dieu Nguyen , Thi Duyen Bui , Ngoc Chien Nguyen
Published: September 2023

The pharmacokinetics of clarithromycin (CLR) conventional tablets (T1/2: 5-7 h) demand 2 or 3 doses per day, which is inconvenient for patients. Therefore, a sustained-release CLR tablet is necessary. Based on Klacid MR tablets (AbbVie) composed of citric acid and sodium alginate (Na-ALG), we developed a 24-hour extended-release CLR tablet. Although citric acid had a significant effect on the CLR release profile, the incompatibility of citric acid and CLR was reported (via FT-IR and stability study). Based on the function of Na-ALG in controlling the release and reducing the incompatibility of citric acid and CLR, a process (CLR and citric acid were granulated separately) was proposed. The final tablet formulation showed 1-month stability and dissolution similarity to standard tablets in pH 6.8 medium (f2 > 50).
Hemodynamic and Homeostasis Changes after Continuous Renal Replacement Therapy in Septic Shock Children at Vietnam National Children’s Hospital
Authors: Duy Phuc Tong , Ba Dung Tran , Viet Hung Dau , Anh Tuan Ta , Quang Quan Thieu , Huu Phuc Phan
Published: September 2023

Objectives: This study aims to describe changes in hemodynamics and homeostasis after continuous renal replacement therapy (CRRT) in septic shock children without acute kidney injury. Methods: An observational study was conducted in the pediatric intensive care unit (PICU) at Vietnam National Children’s Hospital from January 2018 to June 2022. Children aged under 18 years old with septic shock and without acute kidney injury who required CRRT were analyzed on demographic factors, baseline clinical and laboratory results, changes in hemodynamics and homeostasis at 6 hours, 12 hours, 24 hours, 48 hours, 72 hours, 4 days and 5 days after CRRT initiation. Results: A total of 125 children (male, 57.6%) were enrolled in the study. The median age was 11.5 months (IQR: 5 – 29). Overall PICU mortality rate at day 28 was 40.8%. Among survivors, there was a statistically significant improvement in heart rate, mean blood pressure, vasoactive inotropic score (VIS), and pH at all mentioned periods after CRRT initiation. Lactatemia statistically significantly decreased after 24 hours of CRRT initiation (p < 0.05). Among non-survivors, there was a statistically significant improvement in heart rate at all the periods and in mean blood pressure at 6 hours and 12 hours, while there was no improvement in VIS, pH, and lactatemia. Conclusion: CRRT played an important role in stabilizing hemodynamics and homeostasis in septic shock children without acute kidney injury.
Screening In Silico Lipase Inhibitory Activity of Various Coumarin Compounds for the Treatment of Obesity
Authors: Thanh Tung Bui , Thi Huong Le , Thi Hong Hanh Nguyen , Hai Ha Nguyen
Published: September 2023

Currently, obesity is one of the most common diseases and accounts for a high rate in many countries. Pancreatic lipase (PL) is the major enzyme secreted by the pancreas that has a direct effect on the formation of monoglycerides and free fatty acids. Inhibition of pancreatic lipase enzyme helps to break down fat, reduce kCal, and lose weight. Coumarins are a group of compounds that are active in obesity. Therefore, our study aimed to evaluate and screen coumarin compounds effective in inhibiting lipase enzyme by molecular docking method. As a result, we obtained eight compounds showing lower binding energy values than the positive control Orlistat and satisfying drug-like properties when evaluating the Lipinski rule of five. After that, these compounds continued to analyze pharmacokinetic and toxicological properties (ADMET) to obtain three compounds with the best results: Peucenidin, Edultin, and Xanthalin with good intestinal absorption, well distributed to tissues, metabolized by the liver, hepatic metabolism, renal excretion, and low toxicity. Therefore, further in vivo and in vitro studies are needed to develop drugs for the treatment of obesity.
Assessment of the dynamics of the quality of life of the population of the Kulundinsky district of the Altai Territory
Authors: Varaksina Natal'ya Vladimirovna , Varaksin Sergei Vladimirovich , Zamyatina Olga Nikolaevna , Koda Egor Aleksandrovich , Zamyatin Ivan Denisovich
Published: September 2023

The article deals with the topical issue of the quality of life of the rural population on the example of the Kulundinsky district of the Altai Territory. The methodology of quality of life research is based on structural functionalism and symbolic interactionism. The study of the quality of life was carried out by both qualitative and quantitative methods, and the components of the quality of life themselves were based on both objective and subjective levels. Methods such as a questionnaire survey of the population, an expert survey in the form of an in-depth interview, a focus group, and document analysis were used in the work. This article presents the results of a sociological study in the period from 2022 to 2023, which allows you to track the small dynamics of the quality of life of the rural population, to detect real changes associated with objective and subjective parameters. The novelty of the study lies in a comprehensive assessment of the dynamics of the quality of life of the rural population of a particular municipality, which allows us to study the issues of the quality of life of the population at a deep level, both at the empirical level and at the level of theoretical generalizations. The results of the sociological research showed that a number of objective components of the quality of life have noticeably increased compared to the previous year, as for the subjective component, we can also state some improvement, since the population feels real care about itself in the person of the district administration, village councils and the government of the region. Special attention should be paid to the need to extrapolate the methodology of this sociological study to other areas of the Altai Territory, which allows the relevant competent authority to track point-defined problems and promptly resolve them.
Survey on protocols focused on adhesion procedures adopted by dentists
Authors: Rodrigues Lorena dos Santos , Mello Paula Sampaio , Almeida Tereza Jacy da Silva , Freitas Mariana Itaborai Moreira , Fraga May Anny Alves , Finck Nathalia Silveira
Published: September 2023

Objective: The aim of the current study is to assess protocols focused on adhesive procedures practiced by dentists who work in Espírito Santo State (ES), based on questionnaire application. Methods: Dentists working in ES were invited to complete a virtual questionnaire about adhesion procedures associated with their clinical practice. Participants’ responses were tabulated for descriptive analysis purposes and compared to each other, based on the success/failure rate in restorative procedures reported by these professionals and on their understanding about the concept of adhesion. Collected data were subjected to statistical analysis based on using the Chi-square or Fisher's exact test, depending on the case. Results: One hundred and eighteen (118) professionals completed the questionnaire. Approximately 83.9% of them reported low failure rate in their restorative procedures, whereas 16.1% reported high failure rate. Moreover, 95.8% of participants reported to know the concept of adhesion, whereas only 4.2% reported not know it. Conclusion: It is possible concluding that, despite the low rate of failure in, and knowledge about, adhesion reported by the herein interviewed professionals, their knowledge about protocols on adhesive procedures to be adopted by dentists in ES remains incipient.
IS CHRISTIANITY STILL UP-TO-DATE? AN ANTHROPOLOGICAL ARGUMENT
Authors: CHIȘ Ioan-Tănase
Published: September 2023

In a world dominated by newness, the question we start with is inevitable: is Christianity still relevant today? For believers and religious affiliates, the question is superfluous; but it falls to them to deliver valid answers, even to such rhetoric. Where will they build their argument from? From a God whom the opposing camp has long since disqualified? We believe that one of the common, valid premises for effective dialogue and constructive criticism is the human being itself. Man is the immediate reality, impossible to neglect, which is the concern of both believers (a being destined to fulfilment through deification, legitimised as a person by God) and non-believers (a being legitimised by itself). The evolution of this being becomes the control lamp of ontological truth and implicitly contains the answer to our question. We have analysed, comparatively, two vectors, two potential directions relevant to human evolution. The first is described in two landmark works of literature, The Abolition of Man and The Brave New World, and the other through a summary of the orthodox Christian anthropological paradigm. In the case study I have developed, I have come to the conclusion that in the manner in which man undergoes a rationalistic immanent reductionism, becoming merely nature, he becomes himself a piece of nature and seals his demise through dehumanization, becoming himself an idol without consciousness. At the same time, if he empowers his inner, spiritual universe and tries to establish himself in the mystery of the personal God by relating correctly to nature, i.e. to the nature within him, he will find himself in the position of the saint who has risen above nature by the spiritual discipline of instincts. Here true reason and full freedom are revealed. So, despite hostile social pressure, Christianity is not only relevant today but, along the lines of this argument, necessary.
MOVEMENT AND ITS STABILITY AS AN ARGUMENT FOR CREATION, IN THE CAPPADOCIAN FATHERS
Authors: BUTE Cristian Florin
Published: September 2023

The Cappadocian Fathers consider that the orderly movement of creatures and, especially, the stability of heavenly bodies is an indication of the existence of the Creator and divine providence. In St. Basil the Great we find a version of the argument of the First Mover from Aristotle, developed also by Thomas Aquinas. In St. Basil the Great and St. Gregory of Nazianz, as in Aristotle, the question of the existence of movement was posed not only in the sense of an original impulse towards movement, but also for the continuation of movement once begun. The sustaining in motion had to have a cause outside the one being moved. And St. Gregory of Nyssa shows that the stability of the movement of heavenly bodies is a witness of divine proneness, as a sign of the specificity of the uncreated, which is unchangeability, in contrast to the attribute of change that dominates the creature. The Cappadocian Fathers do not base faith on reason, but by rational arguments and facts of nature they strengthen the solidarity between faith and reason and clear the obstacles, coming from wrong philosophies, which obstruct the channels through which natural revelation inspires manry
Remote Learning and Stress in Mothers of Students with Attention Deficit and Hyperactivity Disorder during the Covid-19 Lockdown
Authors: Cvitković Daniela , Wagner Jakab Ana , Stošić Jasmina
Published: September 2023

The Covid-19 lockdown and the implementation of remote learning brought challenges to children with ADHD and their parents. This research aimed to examine the spatial and technical preconditions and quality of support for children with ADHD during remote learning and to determine their mothers’ burdens with the children’s school tasks during the first lockdown. Another aim was to determine the degree of academic accommodation of teaching, the mother’s burden with the school tasks, and the impact of the intensity of the children’s difficulties on mothers' stress levels. The study had 61 mothers of children with ADHD, aged 30 to 53, as participants. Data were collected using an online questionnaire. The perspective of mothers showed that spatial conditions were not appropriate for holding online classes. Furthermore, teaching materials during online classes were not adapted to the child’s needs, teachers did not send teaching materials through the available online services in a proper manner, and more than a third of the mothers stated that there was no interactive teaching at all and that there was no individual contact with teachers. Most mothers state that they are burdened with the child’s school tasks more than compared to the period before the lockdown. It has also been shown that attention symptoms, lack of academic accommodations, and school workload have statistically significant effects on maternal stress.
Research from Low-Income and Middle-Income Countries will Benefit Global Health and the Physiotherapy Profession, but it Requires Support
Authors: Sharma Saurab , Verhagen Arianne , Elkins Mark , Brismée Jean-Michel , Fulk George D. , Taradaj Jakub , Steen Lois , Jette Alan , Moore Ann , Stewart Aimee , Hoogenboom Barbara J. , Söderlund Anne , Harms Michele , Pinto Rafael Zambelli
Published: September 2023

Disparities in research publications are common in the physiotherapy and rehabilitation fields.1 A small proportion of published research arises from low-income and middle-income countries (LMICs),1,2 home to 85% of the world’s population. Systems-level, institutional-level, and individual-level factors contribute to these disparities. With urgent and unified actions, global health and the standard of physiotherapy research in LMICs can be improved and strengthened. In this editorial, we will discuss the challenges encountered by researchers from LMICs in conducting and publishing high-quality research and propose potential strategies to address these challenges.
Effects of Psychological Antecedents of Engagement on Organizational Performance: Mediating Role of Employee Engagement
Authors:   School of Management, Universiti Sains Malaysia, 11800, Minden, Gelugor, Penang, Malaysia, Sulaiman Abdullah Adewumi , Abdullah Effendi Azura ,   School of Management, Universiti Sains Malaysia, 11800, Minden, Gelugor, Penang, Malaysia, Aladwan Saif Isam ,   School of Management, Universiti Sains Malaysia, 11800, Minden, Gelugor, Penang, Malaysia
Published: September 2023

This study aims to assess the influence of psychological antecedents of engagement on the performance of public sectored organizations in a developing nation within the context of human resources management and public sector management. The study proposed a conceptual model comprising 7 hypotheses tested with employment of the structural equation modelling-partial least squares. Data was gathered using structured questionnaire from 303 public employees from 10 public sectored organizations in Nigeria. The results revealed that of the three main psychological antecedents of engagement, psychological meaningfulness antecedents of engagement and psychological safety antecedents of engagement directly influenced employee engagement. However, no effect was found for psychological availability antecedents of engagement. The finding also showed that employee engagement mediates the relationship between psychological antecedents of engagement and organizational performance. The most significant effect was established in the relationship between psychological meaningfulness antecedents of engagement and employee engagement. The limitation of this study relates to its generalizability because it focuses on only the public sector organization. Additionally, it is cross-sectional research, and the lack of time which a longitudinal study will have could make the findings broader than it is.
Understanding Lean Awareness Gaps between Management and Operations in an Aerospace Manufacturing Company in Malaysia
Authors:   School of Technology Management and Logistics, Universiti Utara Malaysia, Ahmad Zaidi Mohamad Faizal , Mohd Rosdi Siti Asma' ,   Faculty of Management and Economics, Universiti Pendidikan Sultan Idris, Abd. Hadi Fatimah-Salwa ,   Faculty of Management and Economics, Universiti Pendidikan Sultan Idris, Belal H.M. ,   Liverpool Business School, Faculty of Business and Law, Liverpool John Moores University
Published: September 2023

Lean planning is usually performed by the management team, while lean implementation by the operations team. Lean implementation can be more successful if the gap in lean between the management and operations teams are understood. By knowing the gaps, the right resources can be allocated to the right people doing the right things. This study aims to investigate the gap in lean awareness between both teams. The survey, via Google Form, took place in an aerospace manufacturing company in Malaysia. 360 valid responses received and analyzed with SPSS. Based on the findings, the management team was found to have more working experiences with higher qualifications compared to the operations team. Consistently, the findings have also found the management team has better awareness on lean terminologies, types of waste, and benefits of lean, followed by the technicians and operators, respectively. As a result, there was a clear gap in lean awareness between the management and operations teams. This gap might possibly be influenced by the level of qualifications, and number of experiences. Meanwhile, the findings within the operations team have shown the technicians' awareness on lean is better than the operators. This study implicates that a specific lean awareness program should be designed to suit different level of understanding on lean, for the right people with the right resources. With effective lean program, the implementation will be more successful, and firms can achieve better efficiency and waste reduction.
Managing Organizational Risk to Avoid Dispute For DX
Authors:   IT Dispute Institute of Lessons Learned, 2440803, Yokohama, Japan, Ohtaka Hiroshi
Published: September 2023

Although not only information technology (IT) systems but also collaborative work with IT vendors and IT users are indispensable for digital transformation (DX), disputes between IT vendors and IT users (IT disputes) have often been observed, after the abortions of IT projects and successive claims to compensate for individual losses. The vendors and users waste tremendous resources as well as opportunities, however, the root causes of IT disputes and measures to prevent similar incidents are not clarified. Lessons learned from such disputes have not been identified specifically enough to prevent the same troubles in the future. The goal of this paper is to identify the lessons learned. Applying a new analytical technique for troubled IT project cases, we identify individual root causes and business risks, whose threats have been overlooked by organizations, and derive the lessons learned. We also show specific management practices for avoiding the same disputes based on the lessons learned. Moreover, after showing that current institutes of project management have not considered the risk and have not involved the lessons learned in the management standards, we propose a revised organizational project management standard with specific practices for less loss of our social and economic activities in the future DX era.
Street Politics in Thailand During 2019 To 2022
Authors:   Graduate School, Chulalongkorn University, Bangkok, 10330, Bangkok, Thailand, Zhang Wending
Published: September 2023

The Covid-19 pandemic was adversely affecting Thailand amidst strong attacks especially by the youth groups on the government. The main force of Thai youth protests has made street politics in Thailand different from those of the past. By problematizing this emerging phenomenon, this paper proposes to tackle two research questions. How are the protests in Thailand during the Covid-19 pandemic different from those the past? How does the massive outbreak of protests generate implications for present and future Thailand? Therefore, this paper combines the theories of Radical Politics, Digital Activism and Contentious Politics, adopts qualitative research, mainly through documentary analysis, interviews and questionnaires to conduct a constructive research, to explore the development, changes and implications of street politics in Thailand during 2019 to 2022. This paper argues that the youth protests which took place in recent years have had a huge impact on many aspects of Thailand, but also had their shortcomings which, coupled with the strength of the government’s counter-measures to protests, led to continued but ineffective activities, with multiple conditions ultimately triggering a new period of deadlock in Thai political modernization. The paper tries to explain new methods of protest and counter-measures to protests, illustrating the impacts of social media on protests under the pandemic, and hoping in this way to enrich research on the development of street politics in Thailand and completes the research on the political participation of contemporary youth and its impact.