bluuebunny/crossref_metadata_2025 huggingface dataset:
Peningkatan Ekonomi Keluarga Melalui Pemanfatan Limbah Rumah Tangga Menjadi Minuman dengan Nilai Ekonomis (Studi kerjasama dengan Dinas Lingkungan Hidup Pemerintah Kota Tangerang)
Authors: Wicaksono Baghas Budi , Satrianto Heri , Kusnawan Agus , Andy Andy
Published: November 2022

Penelitian ini bertujuan untuk mengilustrasikan pengabdian kepada masyarakat yang telah diimplementasikan oleh Tim Dosen Fakultas Bisnis Universitas Buddhi Dharma yang mengambil topik ekonomi lingkungan. Dalam rangka menjalankan salah satu fungsi tridharma tersebut, Tim Dosen Universitas Buddhi Dharma didukung oleh Dinas Lingkungan Hidup Pemerintah Kota Tangerang dalam implementasi program pemberdayaan masyarakat di Kelurahan Periuk RW 09. Adapun tema pada pengabdian masyarakat, yakni pengelolaan limbah rumah tangga berupa limbah makanan menjadi minuman yang sehat dan memiliki nilai Ekonomi. Berdasarkan program pengabdian pada masyarakat, terdapat beberapa identifikasi masalah, yakni sebagai berikut : (1) Warga RW 09 Kelurahan Periuk belum memiliki pengetahuan mengenai ekonomi sirkular dan pengolahan limbah rumah tangga, (2) Warga RW 09 belum memiliki mitra yang mumpuni dalam melakukan pengolahan limbah rumah tangga secara berkelanjutan, (3) Warga RW 09 Kelurahan periuk belum memiliki infrastruktur ataupun peralatan dalam praktik pengolahan limbah rumah tangga. Adapun ditinjau dari program pengabdian kepada masyarakat yang telah dilaksanakan, yakni memiliki hasil sebagai berikut : (1) Warga RW 09 merasakan manfaat yang signifikan dari adanya program pengolahan limbah rumah tangga, (2) Warga RW 09 memiliki mitra dalam program ekonomi sirkular dan pengolahan limbah rumah tangga serta hilirisasi produk, (3) Warga RW 09 dibekali dengan peralatan untuk membuat pupuk kompos, akses terhadap pengelolaan bank sampah, serta komunitas dengan RW di kelurahan lain dalam hal kerjasama ekonomi sirkular.
Pelatihan Produk Bioteknologi untuk Praktikum Biologi Bagi Guru SMP di Kabupaten Tanggamus Propinsi Lampung
Authors: Handayani Kusuma , Ekowati Christina , Kanedi Sumardi, M.
Published: November 2022

Improvements in the quality of education from year to year are always strived for, both at the elementary, secondary, and tertiary levels. Efforts to improve the quality of education are influenced by the curriculum, textbooks, learning media, learning methods, and evaluation systems. The teacher as one of the spearheads in the community learning process does not escape the problem which is a problem for all levels of society. In the field, there are still many junior high school science teachers who have an inadequate background in Biology, especially in the field of Biotechnology. From the results of the initial survey, it can be seen that the condition of junior high school (SMP) teachers, especially in the field of science studies in Tanggamus Regency, that knowledge about the manufacture of fermented products is very minimal. Therefore, training is needed, so that junior high school science teachers can enrich Biology teaching materials related to biotechnology. This training activity is expected to be useful in helping science teachers in enriching learning materials in the field of biology in junior high schools and provide input for related institutions in improving the quality of teachers to become professionals. This service activity is carried out with several activities, namely lectures and direct practice of making biotechnology products such as kefir, yogurt, and tempeh. Evaluation of these activities will be carried out at the beginning of the training, during the training process, and at the end of the training. more than 50% of there were 3 participants at the time of the posttest
ANALISIS KINERJA KEUANGAN MENGGUNAKAN METODE ECONOMIC VALUE ADDED (EVA) DAN FINANCIAL VALUE ADDED (FVA) (STUDI KASUS PADA RUMAH SAKIT MITRA KELUARGA TAHUN 2017-2021)
Authors: Oktavia Sri Nur , Hartati Nani
Published: November 2022

Perusahaan yang bergerak dalam bidang kesehatan salah satu yaitu Rumah Sakit Mitra Keluarga. Rumah sakit yang bergerak pada bidang kesehatan serta beroperasi hampir di seluruh Indonesia dan sebagai salah satu rumah sakit terbesar di Indonesia. Di masa pandemi seperti sekarang ini rumah sakit harus mampu bersaing dengan rumah sakit lainnya, seperti dengan cara rumah sakit harus bisa meningkatkan kinerjanya, kinerja dalam melayani pasien atau bahkan kinerja keuangannya. Kondisi keuangan rumah sakit yang tidak stabil tentunya sangat berdampak besar terhadap kinerja keuanga rumah sakit.  Sehingga perlu dilakukan pengukuran kinerja untuk mengetahui kekuatan dan kelemahan rumah sakit. Kinerja keuangan suatu perusahaan dapat dinilai dengan menggunakan beberapa alat analisis keuangan, salah satunya pengukuran kinerja berdasarkan nilai (Value Based) yaitu Economic Value Added (EVA) dan Financial Value Added (FVA).    Tujuan dari penelitian ini adalah untuk mengetahui gambaran kinerja keuangan pada Rumah Sakit Mitra Keluarga yang diukur menggunakan metode Economic Value Added (EVA) dan Financial Value Added (FVA) pada tahun 2017 sampai dengan tahun 2021. Metode penelitian yang digunakan adalah metode penelitian kuantitatif, sumber data yang diperoleh adalah data sekunder. Metode pengumpulan data menggunakan metode dokumentasi dan metode studi kepustakan. Hasil penelitian ini menunjukkan bahwa kinerja keuangan Rumah Sakit Mitra Keluarga tahun 2017 sampai 2021 menggunakan metode Economic Value Added (EVA), Rumah Sakit tidak mampu menciptakan nilai tambah ekonomi yang mengarah pada kinerja yang buruk (EVA<0). Tetapi kinerja keuangan Rumah Sakit yang diukur menggunakan Financial Value Added (FVA) menghasilkan kinerja yang baik karena Rumah Sakit sudah mampu menghasilkan nilai tambah finansial (FVA>0).
PENERAPAN METODE SIMPLE ADDITIVE WEIGHTING UNTUK PENILAIAN DAN EVALUASI KEHADIRAN KARYAWAN PADA PRESENSI BERBASIS QR CODE (STUDI KASUS RITMALL)
Authors: Pertiwi Noviarsih Indah , Suharsono Teguh Nurhadi , Pakpahan Andy Victor
Published: November 2022

RitMall One Stop IT Solution merupakan suatu perusahaan yang bergerak  di bidang jasa pembuatan aplikasi website. Terdapat kendala yang dihadapi pada presensi karyawan di perusahaan ini yaitu dalam presensi karyawan masih dilakukan secara tertulis belum menggunakan sistem terkomputerisasi. Presensi merupakan sebuah pengambilan data guna mengetahui jumlah kehadiran karyawan pada suatu Instansi Pemerintah / Perusahaan. Telah dilakukan analisis pada perusahaan RitMall, dimana kendala yang sering terjadi diantaranya mengisi presensi masih menggunakan kertas dengan cara tanda tangan pada setiap karyawan. Dan terjadi kelemahan dalam kehadiran karyawan untuk mendata kehadiran perbulan akibat laporan presensi yang kurang tepat dan akurat serta dalam penilaian kehadiran sulit untuk ditentukan sebagai bahan evaluasi. Oleh karena itu, dirancanglah sebuah sistem presensi qr code karyawan berbasis website yang memberikan kemudahan dalam presensi dan mempermudah untuk mengelola data karyawan serta dalam penilaian kehadiran karyawan sebagai evalusi maka menerapkan metode Simple Additive Weighting (SAW) untuk mempermudah dalam penilaian karena metode SAW melakukan perhitungan normalisasi dan perangkingan untuk menentukan karyawan mana yang terbaik dalam kehadirannya.
PERANCANGAN SISTEM INFORMASI PERSEDIAAN BARANG MENGGUNAKAN METHODOLOGI SCRUM (STUDI KASUS: MINI MARKET IBU WATI)
Authors: Aspahani Syifa , Purnama Asep Muhammad Indra
Published: November 2022

Peran sistem informasi sangat diperlukan di era globalisasi saat ini untuk mendukung berbagai jenis aktivitas. Diantaranya membagikan informasi yang efektif dan akurat, mengelola data perusahaan dalam jumlah tidak sedikit dengan baik, serta membantu perusahaan membuat keputusan yang tepat dalam mengembangkan strategi dan kebijakan perusahaan. Minimarket sayuran merupakan UMKM yang bergerak di bidang kebutuhan pokok  yang tepatnya berlokasi di Jalan Cikutra, Pasar Cikutra. Saat ini aktivitas pengelolaan data Minimarket Sayuran masih dilakukan secara manual. Setiap aktivitas keluar dan masuk barang hanya di catat sesuai dengan persediaan barang dagangan yang tersisa, atau terkadang hanya menggunakan kwitansi sebagai bukti barang keluar dan masuk. Pada jenis kegiatan persediaan ini, terdapat potensi keterlambatan pelaporan persediaan dan kesalahan pencatatan mutasi persediaan karena banyaknya jenis persediaan barang yang berbeda-beda. Dengan adanya sistem ini, dimulai dari proses pendataan barang keluar masuk, hingga pelaporan menjadi terkomputerisasi. Dalam penelitian ini menggunakan methodologi scrum.
Controlled aqueous two-phase droplet generation by pressure-assisted microfluidic flow focusing
Authors: Moon Byeong-Ui , Jones Steven G. , Hwang Dae Kun , Tsai Scott
Published: November 2022

We present a technique that generates droplets using ultralow interfacial tension aqueous two-phase systems (ATPS). Our method combines a classical microfluidic flow focusing geometry with precise frequency-controlled inlet pressure, to form monodisperse ATPS droplets. The dextran (DEX) disperse phase enters through the central inlet with variable on-off pressure cycles controlled by a pneumatic solenoid valve. The continuous phase polyethylene glycol (PEG) solution enters the flow focusing junction through the cross channels at a fixed flow rate. The on-off cycles of the applied pressure, combined with the fixed flow rate cross flow, make it possible for the ATPS jet to break up into droplets. We observe different droplet formation regimes with changes in the applied pressure magnitude and timing, and the continuous phase flow rate. We also develop a scaling model to predict the size of the generated droplets, and the experimental results show a good quantitative agreement with our scaling model. Additionally, we demonstrate the potential for scaling-up of the droplet production rate, with a simultaneous two-droplet generating geometry. We anticipate that this simple and precise approach to making ATPS droplets will find utility in biological applications where the all-biocompatibility of ATPS is desirable.
Optimalisasi Perencanaan Tambang Berdasarkan Pemilihan Kebutuhan Alat Berat Untuk Mencapai Target Produksi di Tambang Besar (TB 2.2) Tempilang Front 1 Kec. Tempilang Mitra PT Timah (Persero) Tbk
Authors: Supriyadi Supriyadi , Mardiah Mardiah , Akuan Abrianto
Published: November 2022

Mining activities in TB 2.2 TempilangSite was conducted by Bahtera Sarindo Utama as a partner of PT Timah (Persero) Tbk.The method and technology used in mining site was Mechanical Mine as an alternative of conventional open pit mining which had been applied to overcome  a great lack of hydraulic mining. There were several problems occurred in tin mining activities of TB 2.2 Tempilang included less of cycle time of gravel pump per day due to several problems that appeared in mine site such as gravel pump were often broken, Front Work landslides, so the production activity was inefficient. Mine planning of Mining mechanical methods plan Mechanics in TB 2.2 TempilangSite had production target of 320 m3 / h or 5,760 m3 / day. Therefore it was necessary to optimize the mining design to make it more efficient. The study included the election needs of load haulage equipment  and conveyance based fleet to achieve production targets.Based on the results obtained, the need of equipment in hydraulic mine method  for IDH work Front 1 to achieve production target was4 units of hydraulic pump, 4 units of gravel pump, 3 units of Excavators and 4 units of Articular Dump Truck  with the total production of 5,976 m3 / day, and  if using mechanical mine methodthe needs of load haulage equipment and conveyance for IDH removal was 1 fleet, 2 units of CAT 320D2 Excavator and 6 units of CAT 740B ADT with a total production of 6588.00 m3 / day with the production rate at 9.20 % greater than hydraulic mine and fleet 2 such us 1 unit of 345D CAT Excavator and 6 units of CAT 740B ADT 6 with the total production of 6468.12 m3/ day with the production rate at 7.60% greater than hydraulic mine.Based on the results obtained, mine lifetime of TB 2.2 TempilanFront 1 was 6,13 years using hydraulic mine method, 5,57 years for Mechanical mine of fleet 1 and 5.67 years for fleet 2. From these results suggested, that would better to use mechanical mine method in the removal of IDH in TB 2.2 Tempilang. With the availability of load haulage equipments and conveyance would counduct with fleet 1.
Analisa Kestabilan Lereng Menggunakan Metode Fellenius Secara Manual dan Software Slide Rocscience 6.0 (Studi Kasus : TB 1.42 Pemali PT Timah (Persero) Tbk
Authors: Tiambunan Damos , Irvani Irvani , Fahraini Ferra
Published: November 2022

A hill slope is a part of a mining, especially mining by Open Pit Method. The TB 1.42 Pemali PT Timah (Persero)Tbk, which is often referred as the TB 1.42 applies the open it method in its mining, hence the condition of the hill slope greatly influences the mining Safety because hill slope instability can cause avalance. Hance, the hill slope stability has to be calculated.The calculation is performed to get the value of the safety factor (FK) and to understand the slope’s condition. This calculation can be done using yheFelleniusMethod, either manually or using,SoftwareSlideRocscience 6.0. The FelleniusMethod requires the shear strength parameter in the calculation, therefore a laboratory testing is performed using direct shear test ASTM D-3064-04. This test generates the value of cohesion (c),the angle of internal friction (ɸ) and the soil density (γ) of a soil sample taken from the field.Basedon the research the front south slope TB 1.42 Pemali have sandy loam lithology (Slope LT01), clay (Slope LT02 dan LT03), and gravelly clay (slope LT04). Based on the Fellenius Method, the value of FK for the slope is affected by the slope’s angle and shear strength parameter ( c and ɸ). The analysis conducted in this study showed that of the four slopes that are observed, there are two unstable slopes, which are slope LT02 with FK amounted to 0,809  (manual) and 0,877  (slide), which is unstable ; and the slope LT03 with FK amounted to 1,056 (manual) and 1,070 (slide), which is in critical condition. In order to solve the instability of the slope, PT Timah (Persero) Tbk. Can alter the slope’s geometry and install a grouted tieback anchors at unstable slopes.
Evaluasi Keserasian Kerja Alat Gali Muat dan Alat Angkut Guna Pencapaian Target Produksi Batugamping 350.000 ton/bulan pada Pit 242 Bukit Karang Putih PT Semen Padang (Persero) di Kecamatan Lubuk Kilangan Sumatera Barat
Authors: Adilah M.Arief , Tono E.P.S.B Taman , Andini Delita Ega
Published: November 2022

The tendency of increasing demand for limestone as one of the raw materials for making cement, it is necessary to have appropriate mining to fulfill these needs. The importance of synchronization of loading and hauling equipments in working optimally and efficiently will influences the ability of mechanical devices in productivity. Match factors can find out the comparison of the number of loading and hauling equipment working in mining operations. Analysis of the calculation of match factors based on the circulating time of mechanical devices and the number of devices operating, data taken 30 times a month in July 2018. The primary data such as; circulation time of mechanical devices, resistance factors, bucket and vessel real capacity, effective working time of devices and number of devices, while secondary data such as; devices specifications, devices and operator work time, layout maps, rainfall and company production targets. The research method used is the calculation and analysis of quantitative data on factors that influence the ability of mechanical devices in production. The production target for limestone mining in pit 242 is 350,000 tons / month using a Hitachi ex 2500-6 Excavator unit synchronized with five units of Dumptruck Komatsu HD 785-7. Current devices production capability is 262,198.66 tons / month with a value factor of 0.80. The problem that occurs is not yet achieved the planned production target, this is due to the still low effective working time and work efficiency as a result of existing constraints. Efforts to increase production can be done by improving the effective working time of initially 637.99 minutes per day to 707.30 minutes per day or 81.29% of the total available working time, adding the number of bulk filling to 6 times and adding transportation equipment as many as two units, so that production increased to 361,415.82 tons per month and the value of the match factor for mechanical devices increased to 0.96.
Optimalisasi Shaking Table Dalam Pencucian Bijih Timah Low Grade Di PPBT Pemali Kabupaten Bangka PT Timah Tbk
Authors: Nasution1 Siti Halimah , Irvani Irvani , Rosita Alfitri
Published: November 2022

Tin ore processing is carried out by one of the companies namely Pemali PPBT or Tin Ore Processing Center. PPBT uses SHP feeds (leftover processing results) as material used with standard levels of ± 20% Sn. This feed will then be processed first using a water table, where the results of this process are concentrated, middling and tailing products. Concentrate with high levels while middling ranges from ± 5% Sn. This feed middling air table will be processed again with the shaking table. The increase in levels that occurred during the washing process with the shaking table only increased by 10-15%. This is because there are still many looses of minerals which are followed towards middling and tailings. Therefore it is necessary to increase the level with the trial method on setting the shaking table variables such as the washing water rate of three trials namely 4,201.7 liters / hour, 2835.3 liters / hour and 829.9 liters / hour, and on the variables slope three times the test is 2.8ᵒ, 3.8ᵒ and 4.7ᵒ. As a result of this process, the shaking table has increased levels from before processing 4-6% Sn, after being processed in the shaking table in PPBT it has increased by 10-40% Sn. Optimization of Sn and recovery levels in the right shaking table for the type in PPBT is the washing water rate of 2835.3 liters / hour with levels of 40.64% Sn and recovery of 63.6%. Slope of 3.8ᵒ with a level of 22.16% Sn and recovery of 57.0%. In combination No. 6 (3.8ᵒ and 829,9 liters / hour) with levels of 40.36% Sn and recovery 49.7%.
Identifying the drivers of structural complexity on Hawaiian coral reefs
Authors: McCarthy OS , Smith JE , Petrovic V , Sandin SA
Published: November 2022

Habitat structural complexity is created by biotic and abiotic processes that operate over a range of scales. This can be seen clearly on coral reefs, where corals and reef geomorphology create structure from mm to km scales. Here, we quantified the relative contribution of biotic and abiotic structures to habitat complexity using ‘Structure from Motion’, a technology that allows accurate 3D models of environments to be reconstructed from overlapping photographs. We calculated the linear fractal dimension of these models using a virtual analogue of a profile gauge. By adjusting the spacing between profile gauge rods, we partitioned structural complexity into a series of scale intervals. We identified scales that were most indicative of coral cover (0.5-16 cm) and reef geomorphology (16-256 cm). We found that reefs in the Main Hawaiian Islands have more complexity at finer scales than reefs in the Northwest Hawaiian Islands, which we attribute to the latitudinal gradient in coral cover along the archipelago. At coarser scales, islands at each end of the archipelago have sites with high structural complexity, with less complexity in the center of the archipelago. These differences are consistent with geologic factors shaping island uplift, subsidence, and reef formation. In addition, we found that different coral genera and morphologies display unique patterns of fractal dimension, with branchingPoritescorals creating the greatest amount of habitat structure at nearly all scales. This study demonstrates how multi-scale approaches can be used to identify the processes responsible for reef structural complexity and changes in structure over time.
A Case Study of General Education Using Classic English Novels: Focusing on Seoul Theological University's 〈H+Reading Classics and Debate〉
Authors:   The Korean Society of Culture and Convergence, Ahn Dong Hyun , Kim Jin Kyeong
Published: November 2022

This paper aims to re-evaluate classical literature’s fundamental role in liberal education, and propose convergent education that incorporates more English novels. Modern curricula in American universities have systematized the use of classical literature, and since the 2000’s, classical literature has had a significant role in general education in Korea. However, with new focus in convergence education, interest in classical reading education has been dwindling. In order to analyze the possible benefits of classical reading education through English novels, this paper examines two Seoul Theological University courses. These courses show that novels have advantages over other classical literature or genres by being more approachable and interesting. Furthermore, novels are appropriate for convergence education as they deal with complex subjects from many different fields that converge together. English novels in particular are especially beneficial as they allow students to experience foreign cultures and broaden their horizons. For these reasons, we propose that English novels be more actively used in classical reading education.
The Use of the Michael Chekhov Technique to Create a Role
Authors:   The Korean Society of Culture and Convergence, Kim Kyujin
Published: November 2022

This study aims to investigate Michael Chekhov Technique to find a concrete way to create a variety of roles beyond everyday self. The actor tends to copy themselves and reduce the diversity of acting during role creation. Thus, Michael Chekhov emphasizes intuitively imagining and embodying invisible elements, avoiding duplicating themselves. Then, he suggests approaching a character through higher self, which means the many ‘I’s and the expanded body-mind. Among the twenty Michael Chekhov techniques, this research intensively focuses on the principles and processes of Quality, Personal Atmosphere, Psychological Gesture, and Imaginary Center and Body, which can be directly applied to building a role. These techniques actively answer the following questions: ‘How will the character move?’, ‘What space will the role be surrounded?’, ‘What psychological movement will be inside the role?’, ‘What center and body will the character embody?’ Although the points are different, all the skills help the actor speak and move beyond their psycho-physical habits and, by awakening the actor’s higher self, express the inner essence and personality of the role sincerely and colorfully.
The Effect of Influencer Characteristics on WOM Intention (Word of Mouth Intention) among Adolescents
Authors:   The Korean Society of Culture and Convergence, Park Sanhee , Kim Kiyoon
Published: November 2022

This study explored factors influencing influencer channel usage among teenagers who started using mobile media and started forming social relationships through media. According to the results of the analysis, it was found that topicality and reliability, which are perceptions of influencer channels, had a positive (+) effect on self-congruence. It was found that the professionalism of the influencer channel did not affect the self-congruence. In addition, the feeling of homogeneity with the influencer was found to have a positive (+) effect on satisfaction with the influencer channel and word of mouth intention, and satisfaction was found to have a positive (+) effect on word of mouth intention. As a result, it was analyzed that the positive perception of influencers among adolescents has an important effect on future purchase, satisfaction, and word of mouth intentions.
The Analysis of the Relationship among Health Concerns, Regular Physical Activity, Food Consumption Behavior and Health Indicators Applying Complex Sample Design
Authors:   The Korean Society of Culture and Convergence, Park Jaeahm
Published: November 2022

The purpose of this study is to analyze the relationship among health concerns, regular physical activity, food consumption behavior and health indicators. The complex sample design including weight, stratification, cluster variables was applied using the raw data of the 2020 consumer behavior survey for food by Korea rural economic institute. This study found followings through the complex sampling frequency analysis, complex sampling Chi-square, complex sampling regression. First, the high health concerns group showed the higher regular physical activity participation than low health concerns group. Second, the high health concerns group showed the higher healthy eating, safe eating, food label use, food information use than low health concerns group. Third, regular physical activity group showed higher healthy eating, safe eating, food label use, food information use than non-regular physical activity group. Fourth, regular physical activity group showed lower BMI and higher subjective health recognition than non-regular physical activity group.
The Links between Executive Functions, Reading Comprehension and Second Language Proficiency in Learners of English as an Additional Language: Pilot Study
Authors: Alrushoud Ibtehaj , Wang Rui , Ellefson Michelle
Published: November 2022

Many children struggle to comprehend grade-level texts in their first and additional languages despite having adequate decoding and good additional language proficiency. Recent studies often attribute monolingual's poor comprehension to weak executive functions. However, little research has investigated this association in children speaking more than one language. In this small-scale study, eight 9-to -10-year-old (Mage=9.99 years, SD= 0.40 years) learners of English as an Additional Language completed executive functions (indexed by measures of working memory, inhibition and cognitive flexibility), reading comprehension and decoding (words and non-words) in Arabic and in English, and additional language proficiency tasks. Results indicated a positive correlation between Arabic nonword decoding and inhibition efficiency as well as cognitive flexibility efficiency and English language proficiency. Further, findings showed a positive significant association between children’s ability to decode words and non-words in both languages as well as a strong correlation between English words and non-words with English comprehension.
Web Based Health Check Application for Water Management Systems via SNMP Protocol
Authors: Yıldız Hilal , Balta Musa
Published: November 2022

The purpose of this article is to develop a system that will enable the monitoring of smart water systems over the network. In this study, firstly why this system is needed is explained and then the developed application is explained. As described in chapter I, each network must be monitored by its administrators to detect potential cyber-attacks and faults. In critical infrastructures, this is a mandatory condition. Otherwise, a possible cyber-attack or faults in the network may lead to the suffering of thousands of people. The application developed for these reasons has been designed according to user criteria, taking into account the previous applications, as explained in section II. With the developed application, the Critical Infrastructures National Testbed Center water management network can be monitored using the web-based and SNMP protocol, and possible abnormal situations can be easily detected.
The Prolegomena To Christian Missiology
Authors: Soegianto Soegianto , Sibagaring Miduk Sampetua
Published: November 2022

The title of this research article is The Prolegomena To Christian Missiology which discusses evangelism that must be carried out by Christians without exception, God's people are required not only to theorize but to carry out the commands that the Lord Jesus assigned to every believer. The purpose of writing this scientific article is to open up insight to the reader so that they have a broad determination and insight into the notion of evangelism. The conclusions from this study describe the following: first, faithful believers are disciples who are ready to plow and do not look back. Second, every believer must have ideas and actions in proclaiming the truth of God's Word. The Bible is a mission book from the Old Testament to the New Testament. The history of missions is the history of salvation in Christ Jesus the Messiah, the Son of God.
Hubungan Indeks Massa Tubuh (IMT) dengan Tingkat Keparahan Disminore
Authors: Siscadarsih Indraswari , Amanullah Rizqi , Latansyadiena Wafda Ardhian
Published: November 2022

Introduction: Several studies have shown that women who have overweight and obese tend to have more severe dysmenorrhea than women with a normal BMI. The results of the preliminary study that have been carried out, obtained information that students who lived in the Yogyakarta Ministry of Health Poltekkes dormitory for more than six months have a prevalence of underweight of 20.13% and overweight of 25.62%. Purpose: The purpose of this study was to determine the relationship between BMI and the severity of dysmenorrhea. Methods: This research is quantitative using primary data sources with a cross-sectional design. The sample in this study were students of the Department of Midwifery. Sampling using non-probability sampling method by purposive sampling as many as 311 people. Result: The analysis of this study was carried out using multivariate. The results of this study indicate that there is a significant relationship between BMI and dysmenorrhea (p=0.006). In respondents with dysmenorrhea, the OR for having severe dysmenorrhea in obese respondents was 6.3 times, compared to respondents with normal weight. Conclusion: BMI in adolescents with obesity affects the severity of dysmenorrhea so physical activity and nutritional intake need to be considered to reduce body weight.
cleanSURFACES® intervention reduces microbial activity on surfaces in a senior care facility
Authors: Wright Justin R. , Ly Truc T. , Brislawn Colin J. , Chen See Jeremy R. , Anderson Samantha L. C. , Pellegrino Jordan T. , Peachey Logan , Walls Christine Y. , Bess Jessica A. , Bailey Anne L. , Braun Katie E. , Shope Alexander J. , Lamendella Regina
Published: November 2022

As one of the top public health challenges outlined by the Centers for Disease Control (CDC), estimates report that hospital acquired infections (HAIs) claim the lives of 99,000 Americans and cost healthcare providers over $28 billion each year. In addition to underlying conditions related to age, elderly patients in long-term care facilities are at an elevated risk of acquiring HAIs. A large percentage of HAIs is attributable to contaminated surfaces and medical devices. To that end, this study utilized a metatranscriptomic sequencing workflow (CSI-Dx™) to profile active microbial communities from surfaces in the HJ Heinz Community Living Center, a long-term care facility in the Veterans Affairs Pittsburgh Health Care System. Swabs were collected from high-touch surfaces (Keyboard, Ledge, Workstation on Wheels, Worksurfaces) before (Baseline) and after cleanSURFACES® were installed at 4 timepoints (Day 1, Day 7, Day 14, and Day 30). Microbial richness was significantly reduced after cleanSURFACES® intervention (Wilcoxon test with Holm correction, p=0.000179). Beta diversity results revealed distinct clustering between Baseline and Post-intervention samples (Adonis, p<0.001). Reduction in bacterial (Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis) and fungal (Malassezia restricta, Candida albicans, Candida glabrata, and Candida orthopsilosis) expression of opportunistic pathogens was observed. Additionally, a subset of taxa (Corynebacterium, Cutibacterium acnes, and Ralstonia pickettii) was present in specific Post-intervention timepoints and surface types. This study revealed decreased microbial activity, highlighting the potential for the combinatorial application of cleanSURFACES® and regular decontamination practices to reduce the prevalence of microbes causing HAIs.
Finnish and Estonian teachers’ views on the nature of intelligence
Authors: Ronkainen Rina , Kuusisto Elina , Eisenschmidt Eve , Tirri Kirsi
Published: November 2022

The purpose of this study was to investigate Finnish (n= 226) and Estonian (n= 347) teachers’ views on the nature of intelligence. The study utilized a survey that included a qualitative, open-ended question about teachers’ definition of intelligence and the quantitative inventory Implicit Theories of Intelligence (ITI). We then employed a convergent mixed-method design to understand teachers’ views on the nature of intelligence. These views were divided into four main categories: the multidimensional nature of intelligence, manifestational nature of intelligence, developmental nature of intelligence, and creative nature of intelligence. Teachers from both countries highlighted cognitive features, such as memory, information processing, and problem-solving skills, as a part of the multidimensional nature of intelligence. In addition, teachers viewed intelligence as developmental when measured with the ITI inventory, indicating that intelligence is considered incremental. Lastly, when triangulating the qualitative and quantitative data of teachers’ views on the nature of intelligence, only one statistically significant difference was found. Teachers with an entity view of intelligence also mentioned entity features in their own descriptions. The results showed that teachers views’ on the nature of intelligence are rather broad; however, in future studies, teacher interviews and classroom observation might provide even more profound understanding of teachers’ views on this topic.
Gender discrimination in the business school’s C-suite? Evidence from aggregate decomposition approaches
Authors: Caudill Steven B. , Mixon Franklin G. , Faria João Ricardo , Santoyo Julissa Y.
Published: November 2022

Workplace discrimination continues to at least be perceived as a problem by faculty and staff in higher education. The current study extends the academic literature in this area by exploring the possibility of gender discrimination in the wages of academic deans. Using data on deans’ salaries from more than 200 colleges and schools of business in the U.S., we focus our analysis on aggregate decompositions from both the usual Oaxaca-Blinder decomposition approach and the newer inverse probability weighting technique. Aggregate decomposition results from both the usual Oaxaca-Blinder decomposition approach and inverse probability weighting fail to support the existence of gender discrimination in administrative wages in academia. They do, however, support new theoretical research asserting that the publicness of academic administrators’ salaries works to circumvent any wage discrimination based on gender or race.
Metformin use and mortality and length of stay among hospitalized patients with type 2 diabetes and COVID-19: A multiracial, multiethnic, urban observational study
Authors: Miao Emily , Zhang Kaleena , Liu Jianyou , Lin Juan , Yoo Donna , George Claudene J.
Published: November 2022

Introduction

Diabetes mellitus is a common comorbidity among patients with coronavirus disease 2019 (COVID-19). Diabetic patients with COVID-19 have a two-fold increased risk of death and tend to have more severe infection compared to the general population. Metformin, a first-line medication for diabetes management, has anti-inflammatory and immunomodulatory effects. Previous studies focusing on metformin and COVID-19 clinical outcomes have had mixed results, with some showing a mortality benefit or decreased complications with metformin use. To date, few studies have analyzed such outcomes among a diverse, multiracial community.

Methods

This was a retrospective review of patients with Type 2 diabetes and a confirmed COVID-19 infection admitted to an urban academic medical center from January 1, 2020 to May 7, 2020. Baseline characteristics were collected. The primary outcomes of the study were in-hospital mortality and length of stay (LOS).

Results

A total of 4462 patients with Type 2 diabetes and confirmed COVID-19 were identified. 41.3% were Black, and 41.5% were Hispanic. There were 1021 patients in the metformin group and 3441 in the non-metformin group. Of note, more participants in the metformin group had comorbid disease and/or advanced diabetes. We found no statistically significant differences between the metformin and non-metformin group in in-hospital mortality (28.1% vs 25.3%, P=0.08) or length of hospital stay in days (7.3 vs. 7.5, P=0.59), even after matching patients on various factors (29.3% vs. 29.6%, P=0.87; 7.7 vs. 8.1, P=0.23).

Conclusion

While patients had more comorbid disease and advanced diabetes in the metformin group, there were no significant differences with regard to in-hospital mortality or length of stay due to COVID-19 compared to the non-metformin group. Prospective studies are needed to determine if there is clinical benefit for initiating, continuing, or re-initiating metformin in patients hospitalized with COVID-19.
Dissecting lncRNA-mRNA competitive regulatory network in human islet tissue exosomes of a type 1 diabetes model reveals exosome miRNA markers
Authors: Fang Tian , Xue Gong , Jianjun Wu , Wei Long , Xiaomeng Zhang , Fan Yang
Published: November 2022

Background

Emerging evidence shows that exosomes play a crucial role in the occurrence and development of diabetes and its complications. The molecules in exosomes can be regarded as important markers for the diagnosis of diseases. However, it is presently unclear the pathological association mechanism between exosomes and diabetes.

Results

In this study, transcriptome data and lncRNA regulatory association data of human pancreatic islet-derived exosome were integrated to construct the ceRNA network. Network analysis revealed that lncRNA with differential expression were primarily involved in islet insulin secretion signaling pathways, including Hippo, TGF-beta, Wnt, FOXO, Neurotrophin and ErbB signaling pathway. Further, combined with miRNA mediated competitive regulation and differential expression analysis results, potential markers of diabetes were revealed and validated in independent datasets. Finally, we analyzed the mechanisms of diabetes based on the competitive regulatory association and function of lncRNA.

Conclusion

Our results suggest that lncRNA such as lncRNA PVT1, LINC00960 and hsa-miR-107 might be involved in inflammation response in T1DM, and the former lncRNA chose in the present study may serve as novel biomarkers and potential targets for the diagnosis and treatment of T1DM.
Determination of iFGF23 Upper Reference Limits (URL) in healthy pediatric population, for its better correct use
Authors: Brescia Vincenzo , Fontana Antonietta , Lovero Roberto , Capobianco Carmela , Marsico Stella Vita , De Chirico Tiziana , Pinto Carla , Varraso Lucia , Cazzolla Angela Pia , Di Serio Francesca
Published: November 2022

Background

The measurement of Fibroblast growth factor 23 (FGF23) may be useful in the diagnosis and management of abnormal phosphate metabolism in both patients with preserved renal function or with chronic kidney disease (CKD). FGF-23 tests differ considerably by molecule assayed (iFGF23 or cFGF23), analytical performance and reference ranges. We establish iFGF23 Upper Reference Limits (URL) in apparently healthy pediatric individuals using automated immunochemiluminescent assay.

Methods

We measured the levels of plasma iFGF23 from 115 samples from apparently healthy pediatric subjects [59 (51.3%) individuals were male; median age 10 years (range 1–18)] included in an observational study conducted at Policlinico University Hospital of Bari. The method used for the iFGF23 assay was immunochemiluminescent sandwich assay developed by DiaSorin on the Liaison XL platform. Statistical calculation of 95% reference interval, right-sided (CLSI C28-A3) and verification of age and sex covariables was performed for the calculation of the URL.

Results

The URL concentration of iFGF23 was 61.21 pg/mL (58.63 to 63.71, 90% CI). No significant differences were found between the median concentrations of iFGF23 differentiated by sex and age.

Conclusions

The dosage of iFGF23 is important both for the differential diagnosis of the various forms of rickets, and for the subsequent monitoring of the effectiveness of drug treatment. We have established the URL for the iFGF23 Liaison test in apparently healthy pediatric subjects. The availability of iFGF23 pediatric reference values will allow a better clinical use of the test.
Effect of maternal body mass index on the steroid profile in women with gestational diabetes mellitus
Authors: Sun Yanni , Zhu Bo , Meng Xingjun , Yin Binbin , Wu Kaiqi , Liu Yifeng , Zou Dandan , Xue Jianyou , Sun Xiao , Zhang Dan , Ma Zhixin
Published: November 2022

Objective

To explore the effect of maternal body mass index (BMI) on steroid hormone profiles in women with gestational diabetes mellitus (GDM) and those with normal glucose tolerance (NGT).

Methods

We enrolled 79 women with NGT and 80 women with GDM who had a gestational age of 24–28 weeks. The participants were grouped according to their BMI. We quantified 11 steroid hormones profiles by liquid chromatography-tandem mass spectrometry and calculated the product-to-precursor ratios in the steroidogenic pathway.

Results

Women with GDM and BMI<25kg/m2 showed higher concentrations of dehydroepiandrosterone (DHEA) (p<0.001), testosterone (T) (p=0.020), estrone (E1) (p=0.010) and estradiol (E2) (p=0.040) and lower Matsuda index and HOMA-β than women with NGT and BMI<25kg/m2. In women with GDM, concentrations of E1 (p=0.006) and E2 (p=0.009) declined, accompanied by reduced E2/T (p=0.008) and E1/androstenedione (A4) (p=0.010) in the BMI>25 kg/m2 group, when compared to that in the BMI<25 kg/m2 group. The values of E2/T and E1/A4 were used to evaluate the cytochrome P450 aromatase enzyme activity in the steroidogenic pathway. Both aromatase activities negatively correlated with the maternal BMI and positively correlated with the Matsuda index in women with GDM.

Conclusions

NGT women and GDM women with normal weight presented with different steroid hormone profiles. Steroidogenic pathway profiling of sex hormones synthesis showed a significant increase in the production of DHEA, T, E1, and E2 in GDM women with normal weight. Additionally, the alteration of steroid hormone metabolism was related to maternal BMI in women with GDM, and GDM women with overweight showed reduced estrogen production and decreased insulin sensitivity compared with GDM women with normal weight.
Distribution and bioaccumulation of trace metals in urban semi-arid mangrove ecosystems
Authors: Robin Sarah Louise , Marchand Cyril , Mathian Maximilien , Baudin François , Alfaro Andrea C.
Published: November 2022

Mangrove ecosystems are known to act as filters for contaminants between land and sea. In New Caledonia, urbanization has increased along the coastline during the last decades. However, the impact of urbanization on contaminant cycling in mangrove forests has remained unexplored. In this study, we investigated trace metals (TM) dynamics in an urban mangrove soil and their transfer to mangrove tissues for the two dominant mangrove species in New Caledonia: Avicennia marina and Rhizophora stylosa. The results suggest that decades of urban rainwater runoff from an upper neighborhood induced large variations of mangrove soil physico-chemical properties compared to a control mangrove site sharing the same geological watershed. The urban mangrove site had a neutral pH and low salinity in the upper soil, while the control mangrove site presented acidic pH and a salinity ranging from 24 to 62 g L−1. Most TM were significantly less concentrated in the urban mangrove soil varying from 1.3 ± 0.3 μg g−1 at the urban site and 1.9 ± 0.5 μg g−1 at the control site for Cd, to 30 ± 8 mg g−1 and 49 ± 11 mg g−1 for Fe at the urban and control site, respectively. However, higher root bioconcentration factors were measured for As, Cd, Co, Cr, Fe, Mn, Ni, and Pb in the urban mangrove soil (1.7 ± 0.9, 0.14 ± 0.06, 0.23 ± 0.13, 0.042 ± 0.026, 0.088 ± 0.057, 0.47 ± 0.39, 0.21 ± 0.12, and 0.25 ± 0.09, respectively) compared to the control mangrove soil (0.11 ± 0.03, 0.041 ± 0.016, 0.045 ± 0.021, 0.010 ± 0.004, 0.013 ± 0.007, 0.094 ± 0.030, 0.022 ± 0.011, and 0.12 ± 0.03, respectively). The bioavailability of TM in the urban mangrove soil may be favored by suboxic conditions associated to less Cl-TM complexes and pyrite-TM complexes in the soil. Only Cu, Pb, Ti, and Zn, usually associated with urbanization, were more concentrated in the urban mangrove soil with mean concentrations of 27 ± 4, 17 ± 2, 4,571 ± 492, and 62 ± 12 μg g−1 at the urban site, respectively, and 21 ± 4, 10 ± 3, 2,834 ± 541, and 57 ± 12 μg g−1 at the control site, respectively. No significant difference in translocation factors was measured between the two sites, evidencing a regulation of TM translocation to the upper tissues by mangrove trees.
Population genetic structure analysis and identification of backfat thickness loci of Chinese synthetic Yunan pigs
Authors: Qiao Ruimin , Zhang Menghao , Zhang Ben , Li Xinjian , Han Xuelei , Wang Kejun , Li Xiuling , Yang Feng , Hu Panyang
Published: November 2022

Yunan is a crossed lean meat pig breed in China. Backfat thickness is the gold standard for carcass quality grading. However, over 14 years after breed registration, the backfat of Yunan thickened and the consistency of backfat thickness decreased. Meanwhile, no genetic study has been ever performed on Yunan population. So, in this study we collected all the 120 nucleus individuals of Yunan and recorded six backfat traits of them, carried out population genetic structure analysis, selection signals analysis and genome-wide association study of Yunan pigs with the help of their founder population Duroc and Chinese native Huainan pigs, to determine the genomic loci on backfat of Yunan. Genetic diversity indexes suggested Yunan pigs had no inbreeding risk while population genetic structure showed they had few molecular pedigrees and were stratified. A total of 71 common selection signals affecting growth and fat deposition were detected by FST and XP-CLR methods. 34 significant loci associated with six backfat traits were detected, among which a 1.40 Mb region on SSC4 (20.03–21.43 Mb) were outstanding as the strong region underlying backfat. This region was common with the results of selection signature analysis, former reported QTLs for backfat and was common for different kinds of backfat traits at different development stage. ENPP2, EXT1 and SLC30A8 genes around were fat deposition related genes and were of Huainan pig’s origin, among which Type 2 diabetes related gene SLC30A8 was the most reasonable for being in a 193.21 Kb haplotype block of the 1.40 Mb region. Our results had application value for conservation, mating and breeding improvement of backfat thickness of Yunan pigs and provided evidence for a human function gene might be reproduced in pigs.