bluuebunny/crossref_metadata_2025 huggingface dataset:
Wilsons Disease Presenting as Acute Fulminant Hepatic Failure
Authors: Raja Kolluru Karthik
Published: April 2021

Wilson’s disease (WD) is a genetic disorder characterised by mutations in copper metabolism. Adenosine triphosphate (ATPase) ATP7B gene is responsible for disturbance in copper metabolism that leads to accumulation of copper mainly in liver and also in extra hepatic organs (like brain, cornea, heart and kidney).1 Heavy metal accumulation in brain (mainly in basal ganglia) leads to neuropsychiatric manifestations.2 Kayser Fleischer (KF) ring is golden brown ring distributed along the periphery of cornea. It is due to abnormal deposition of copper in the Descemet’s membrane of cornea. Kayser Fleischer (KF) ring is a pathognomonic sign of Wilson’s disease. Fulminant hepatic failure can be the first presentation of WD. Patients presenting with fulminant Wilson’s disease (FWD) clinically present as acute liver failure with encephalopathy and coagulopathy. The mortality of patients is high and orthotropic liver transplantation is the only option, which has been shown effective in patients with Fulminant Wilson’s disease.3 We are report a case of a young male who presented as acute liver failure first time in life and later was diagnosed as FWD.
Entrevista: Edicléa Mascarenhas
Authors: Mascarenhas Edicléa , Jesus Edna Maria de
Published: April 2021

A proposta desta entrevista foi dialogar com a Prof.ª Dr.ª Edicléa Mascarenhas, da UERJ, acerca dos desafios e perspectivas da Pedagogia Hospitalar. A entrevista foi realizada via on-line pela Prof.ª Dr.ª Edna Maria de Jesus, em janeiro de 2021.
ONLINE EDUCATION IN LANGUAGE LEARNING/TEACHING IN UNIVERSITIES: THE COVID-19 AND DIGITAL TRANSFORMATION
Authors: KÜÇÜKLER Halil
Published: April 2021

The Covid -19 pandemic has no doubt changed and fast-tracked the way digital transformation in language learning and teaching is being conducted in higher institutions of learning. Research questions were asked to students and teachers on a voluntary basis to collect substantial data needed to illustrate the influence of digital transformation in foreign language learning and teaching and reveal the effect of digital practice on students. The participants were 103 students and 35 lecturers at the English department at the Komrat University in Gagavuzia. The instrument used for data collection was survey questions. According to the results obtained, 42% of the participants believed that the online platform was foolproof during exams. On the other hand, 71,7% stated that they did not believe that the online platform was more interactive or convenient. These results reveal that higher education institutions involved in teaching on the digital platform need additional skills to ensure they engage students interactively and professionally.
Wetland Fires and Its Environmental Conditions
Authors: Lestari Mona , Andarini Desheila , Camelia Anita , Novrikasari Novrikasari , Nandini Rizka Faliria , Fujianti Poppy
Published: April 2021

Today, many wetlands have been converted into agricultural, industrial, and residential areas. This conversion of land functions creates new problems for the environment and human, one of which is land fires. The results of land fires can also cause other problems that results in losses in various fields, such as human health, the economy, and other fields. The emergence of smog as a result of land fires can cause respiratory problems, disruption of the transportation system, conflicts between neighboring countries, and the others. South Sumatra Province is one of the largest contributors to the haze as a result of land fires, especially its wetlands. Ogan Ilir Regency is one of the areas in South Sumatra Province which has extensive wetlands and fires frequently occur. Fires are caused by triggering factors, one of which is natural factors such as a prolonged dry season, availability of water supply, and intensity of rainfall. This study is an analytic descriptive study that aimed to provide an overview of environmental conditions on land, the majority of which are wetlands which experienced fires in Ogan Ilir Regency in 2019. The environmental conditions studied included soil and vegetation types. The data obtained will be displayed through tables and graphs, then interpreted and analyzed descriptively. The type of data used is secondary data in the form of a report by the Regional Disaster Management Agency Ogan Ilir Regency related to land fires in OI Regency and processed using the Geographic Information System (GIS) application. The results of the analysis show that the area of land fires that mostly occurred in North Indralaya District was 382,7 hectares with a total of 144 hotspots. The burnt area was dominated by peat soil (53%) and scrub vegetation (43%).
Kiai dan Strukturasi Kekuasaan di Pandeglang, Banten
Authors: Hikmawan M. Dian , Godjali M. Rizky , Indriyany Ika Arinia
Published: April 2021

Posisi Kiai dianggap merupakan salah satu kunci penting dalam memahami struktur masyarakat Indonesia. Pada penelitian ini Kiai dilihat sebagai subjek politik dari agensi dan struturasi kekuasaan di Pandeglang. Kharisma dan ketokohan Kiai mampu membuat struktur baru dalam kekuasaan daerah. Keterlibatannya dalam urusan publik membuatnya menjadi agen baru dalam wacana isu publik. Dengan analisis yang lebih ditekankan pada aspek kultural untuk melihat fungsi sosial politik yang diperankan oleh Kiai, penelitian ini menjadi hal yang sangat menarik untuk ditinjau lebih jauh. Dengan metode kualitatif dan pendekatan fenomenologi hermeneutik, penelitian ini mengungkapkan banyak makna dalam melihat struktur kekuasaan yang ada dan memberikan pemaknaan baru dalam melihat relasi kekuasan dalam politik lokal.  Maka dari itu, penelitian ini memberikan gambaran lainnya bahwa ditengah maraknya kekuasaan politik lokal yang dipenuhi dengan oligarki, hasil riset ini menawarkan jalan baru dalam sebuah struktur kekuasaan melalui agensi yang mampu mendorong struktur kekuasaan agar membawa wacana-wacana publik ke permukaan.
Conceptual comparison of the ecogeography-based algorithm, equilibrium algorithm, marine predators algorithm and slime mold algorithm for optimal product design
Authors: Yıldız Betül Sultan , Patel Vivek , Pholdee Nantiwat , Sait Sadiq M. , Bureerat Sujin , Yıldız Ali Rıza
Published: April 2021

Vehicle component design is crucial for developing a vehicle prototype, as optimum parts can lead to cost reduction and performance enhancement of the vehicle system. The use of metaheuristics for vehicle component optimization has been commonplace due to several advantages: robustness and simplicity. This paper aims to demonstrate the shape design of a vehicle bracket by using a newly invented metaheuristic. The new optimizer is termed the ecogeography-based optimization algorithm (EBO). This is arguably the first vehicle design application of the new optimizer. The optimization problem is posed while EBO is implemented to solve the problem. It is found that the design results obtained from EBO are better when compared to other optimizers such as the equilibrium optimization algorithm, marine predators algorithm, slime mold algorithm.
Surface modification of a magnesium alloy by electrical discharge coating with a powder metallurgy electrode
Authors: Elaiyarasan Uthirapathi , Satheeshkumar Vinaitheerthan , Senthilkumar Chinnamuthu
Published: April 2021

The present paper elucidates an experimental study on the surface modification of a ZE41 A magnesium alloy by electrical discharge coating (EDC) process with a tungsten carbide-copper (WC-Cu) powder metallurgy (PM) electrode. Investigated EDC parameters were compaction load, current and pulse on time. Measurement of coating characteristics such as material transfer rate (MTR) and surface roughness (Ra) were undertaken on the coated workpiece. As the design of experiment, response surface methodology was applied and analysis of variance (ANOVA) test was completed to study the influence of process parameters. Mathematical models were developed for coating characteristics to optimize the parameters. In this study, the reliability of the regression model is considered satisfactory with a value larger than 99 %. It was found from the study that the current plays a vital role in increasing the material transfer rate and minimizing the surface roughness of the coated surface followed by compaction load and pulse on time. Various studies such as scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) were carried out to determine the characteristics of the coated layer. These analyses confirmed the presence of the electrode materials in the coated surface.
Distribution of multiple sclerosis lesions detected by brain magnetic resonance imaging in Erbil city
Authors: Tawfeeq Dina , Dawood Shawnam
Published: April 2021

Background and objective: Many epidemiological studies and clinical manifestation studies of multiple sclerosis have been done in Iraq. Up to our knowledge, no such observational study to the radiological feature of the multiple sclerosis lesion has been done yet in Erbil in comparison to other worldwide studies. This study aimed to assess the distribution of multiple sclerosis lesions in brain regions detected by magnetic resonance imaging among Erbil population. Methods: This was a cross-sectional study conducted at the College of Medicine, Hawler Medical University, from April 2018 to July 2019. A review of magnetic resonance imaging scans of the brain of 120 patients was done. Special attention was directed toward identifying the variance in multiple sclerosis lesions distribution in the brain regions and their MR signal intensity characteristics. Results: Periventricular lesions were observed in more than 90% of the study sample. The next common was juxtacortical lesions (24.8%), followed by corpus callosum lesions (16.8 %), while brain stem lesions were the least observed proportions. No significant difference was detected in the distribution of multiple sclerosis lesions among ethnicities and genders, except for basal ganglia lesions, which were significantly more common in women (P = 0.016).The magnetic resonance imaging signal intensity of the lesion was significantly variable among disease duration. Conclusion: The T2 hyper intense lesions were most commonly seen in the periventricular region. Juxtacortical and corpus callosum lesions were also frequently observed. The proportions of the brain stem and cerebellum lesions appeared to be lower in comparison to previous studies. Keywords: Multiple Sclerosis; Magnetic Resonance Imaging; Distribution; Lesion.
Clinicopathological study and immunohistochemical evaluation of cyclin D1 in adenomatous polyps
Authors: Abdulhameed Tenya , Jaff Zheen , Maaruf Nali
Published: April 2021

Background and objective: There are many histological types of colorectal polyps. Most of these polyps are benign epithelial polyps harboring very low risks of cancerous changes. Adenomatous polyps are the most known cancer precursors. Cyclin D1 gene amplification and or overexpression occurs in many human cancers. Cyclin D1 participates potentially in the multistep process of colorectal carcinogenesis. The present study aimed to assess the clinicopathological features of colorectal polyps and evaluate the significance of immunohistochemistry expression of cyclin D1 in adenomatouse polyp as a marker for predicting malignant transformation. Methods: A total of 180 cases of colorectal polyps were collected from Rizgary teaching Hospital and some private laboratories in Erbil, Kurdistan Region, Iraq, from January 2013 to January 2018. All cases underwent polypectomy by colonoscopy for removal of the polyp. Only cases presented with a single polyp were included. The histopathological diagnosis was revised, and the polyps were divided into four subtypes; inflammatory, hyperplastic, juvenile, and adenomas. All adenoma specimens were stained using IHC technique with cyclin D1. Results: Out of the 180 cases, the results showed that 70(38.9%) were adenomatous polyps, 56(31.1%) were hyperplastic polyps,40(22.2%) were juvenile polyps, and 14(7.8%)were inflammatory polyps. Cyclin D1 nuclear staining was detected in 24 (34.2%) adenomas. Statistical significant relations between cyclin D1 expression with male gender and with high grade dysplasia were found. Conclusion: Adenoma was the most common type among colorectal polyps. Cyclin D1 was shown to be aberrantly expressed in colorectal adenomas and may play a role in the early stages of adenoma carcinoma development. Keywords: Colorectal polyp; Cyclin D1; Adenoma.
Will African Federalism Work?; African Unity Twelve Years Later
Authors: Logan Rayford W. , Bissell Richard E.
Published: April 2021

Excerpts from Current History essays published in the 1960s and 1970s.
La cláusula Romeo y Julieta (art. 183 quater del Código penal) cinco años después: perspectivas teóricas y praxis jurisprudencial
Authors: Ramos Vázquez José Antonio
Published: April 2021

En este trabajo se estudia la cláusula Romeo y Julieta del Código penal español, es decir, la exención prevista en el art. 183 quater para aquellos supuestos en que el menor de 16 años ha consentido tener relaciones sexuales con una persona próxima a él por edad y grado de desarrollo y madurez. Este análisis se hace desde dos puntos de vista: el estudio de las posiciones doctrinales existentes hasta el momento (de un lado) y el análisis sistemático de todas las sentencias que han recaído hasta el momento en aplicación de dicha cláusula. A través de ese doble análisis, el lector tendrá una visión clara de qué problemas plantea el precepto y, sobre todo, cómo se está aplicando en la praxis jurisprudencial.
UYKU VE UYANIKLIK BRUKSİZMİ OLAN BİREYLERDE UYKU KALİTESİNİN ARAŞTIRILMASI
Authors: TINASTEPE Neslihan , İŞCAN İpek
Published: April 2021

Amaç:

Bruksizmin
birçok uyku bozukluğu ile ilişkili olabileceği düşünülmektedir. Ancak bruksizmi
olanlarda uyku kalitesi hakkında çok az bilgi bulunmaktadır. Bu araştırmanın amacı
uyku ve uyanıklık bruksizmi bulunan bireylerde uyku kalitesinin araştırılmasıdır.

Gereç ve yöntemler:

Çalışma yaşları 18 ile 35 arasında
değişmekte olan, 351’i (%60) kadın ve 234’ü (%40) erkek olmak üzere toplam 585
dişhekimliği fakültesi öğrencisi ile yapıldı. Uyku bruksizmi tanısında Amerika
Uyku Tıbbı Birliği (AUTB)  tanı
kriterleri kullanıldı. Uyanıklık bruksizmi varlığı öğrencilere yöneltilen son 1
ay içerisindeki diş gıcırdatma farkındalıklarına yönelik soru ile
belirlendi.Öğrencilerin uyku kalitesi belirlenirken Pittsburgh Uyku Kalitesi
İndeksi (PUKİ), gündüz uykululuk derecesi belirlenirken EPWORTH uykululuk
ölçeği (EUÖ) kullanıldı.

İstatistiksel analizler için IBM SPSS
Statistics 22 (IBM SPSS, Türkiye) programı kullanıldı. Çalışma verileri
değerlendirilirken tanımlayıcı istatistiksel metodların (Ortalama, Standart
sapma, frekans) yanı sıra Mann Whitney U, Ki-Kare testi kullanıldı. Anlamlılık
p<0.05 düzeyinde değerlendirildi.

Bulgular:

Ki-kare testinin sonuçları, uyku ve
uyanıklık bruksizmi olan öğrencilerle olmayanlar arasında uyku kalitesi
açısından istatistiksel olarak anlamlı bir fark olmadığını gösterdi. (p˃0.05)
Uyku bruksizmi olan öğrencilerde gündüz aşırı uykululuk görülme oranı (%46.4),
uyku bruksizmi olmayan öğrencilerden (%37.2) istatistiksel olarak anlamlı
düzeyde yüksek bulundu.(p:0.027; p<0.05).

Sonuç:
Bruksizmi olan öğrenciler ile olmayanlar arasında uyku kalitesi açısından
farklılık bulunmazken, uyku kalitesi bileşenlerinde bazı farklılıklar vardır.

Anahtar
kelimeler: uyku bruksizmi, uyanıklık bruksizmi, uyku kalitesi,
parafonksiyon
DENTOALVEOLAR TRAVMA SONUCUNDA OLUŞAN ÖN DİŞ KRON KIRIKLARININ DİŞİN KIRIK PARÇASININ YENİDEN YAPIŞTIRILMASI TEKNİĞİ İLE TEDAVİSİ: DERLEME
Authors: ŞERMET ELBAY Ülkü , ELBAY Mesut , UÇAR Gül
Published: April 2021

Amaç: Bu çalışmanın amacı, ön dişlerde meydana gelen kron kırıklarının tedavisinde,
kırık fragmanın reataçmanı yöntemi kullanılması ile ilişkili olarak yayınlanmış
teknikler, uygulamalar ve materyalleri inceleyen literatürün derlenmesidir. Gereç ve Yöntemler: Pubmed, Google Scholar,
LILACS, Web of Science ve Scopus veritabanlarında  ‘dental trauma’, ‘fragment reattachment techniques’, fracture strength’,’ storage medium’,
‘laser etching’, ‘dentin-bonding agent’, ‘composite resin’ anahtar kelimeleri
kullanılarak yapılan tarama sonucunda, reataçman tekniği ile ilişkili 314 adet
makaleye ulaşılmıştır. Araştırmaya klinik ve laboratuar çalışmaları dahil
edilirken, olgu raporları, derlemeler, özetler ve yayınlanmamış bildiriler dahil
edilmemiştir. Çalışmaya dahil edilen yayınlar, 2 araştırmacı tarafından
ayrıntılı olarak gözden geçirilmiş ve veriler mevcut literatür taraması için
değerlendirilmiştir.Bulgular: Bu derlemede kriterlere uygun olan 35 in-vitro araştırma, 1 adet hem
klinik hem de laboratuar testleri içeren araştırma ve 1 adet klinik
araştırmadan oluşan 37 adet makale incelenmiştir. İncelenen çalışmaların
sınırları dahilinde, kırık parçanın taşıma ortamı, kırık parça yapıştırılırken
kullanılan materyaller ve aşındırma yöntemleri değerlendirildiğinde, sağlam
dişlere benzer kırılma dayanımına sahip dişlerin elde edildiği tespit
edilmiştir.Sonuçlar:  Estetik olarak
hasta ve ebeveynlerin memnuniyet oranlarının yüksek olması ile birlikte, klinik
ve radyografik durum değerlendirmesinin birlikte yapıldığı uzun dönem
sonuçların verildiği prospektif çalışma sayısının sınırlı olduğu tespit
edilmiştir.

Anahtar Kelimeler: dental travma, ‘kırık parçanın yeniden yapıştırılması’, ‘kırılma
dayanımı’, ‘depolama ortamı’, ‘dentin-bonding ajanı’
Farklı Periodontal Hastalık Tiplerinde Tükürük ve Dişeti Oluğu Sıvısı Developmental Endothelial Locus-1 (Del-1) ve Lymphocytw function-associated antigen-1 (LFA-1) Seviyelerinin Değerlendirilmesi
Authors: MUTAFCİLAR Emine , KAYIS Seyit , HAKKI Sema
Published: April 2021

Amaç: Bu
çalışmanın amacı; farklı yıkım paterni gösteren periodontal hastalığa sahip
bireylerde nötrofil adezyon yolağının sıkı adezyon basamağında düzenleyici
sitokinler olan Developmental Endothelial
Locus-1(Del-1) ve Lymphocyte
function-associated antigen-1(LFA-1) tükürük ve dişeti oluğu sıvısı
seviyelerinin değerlendirilmesidir.Gereç ve Yöntemler:Selçuk
Üniversitesi, Diş Hekimliği Fakültesi Periodontoloji Anabilim Dalı’na başvuran
sağlıklı ve sigara içmeyen 42 birey çalışmaya dahil edildi. Klinik ve
radyolojik muayene sonucu Grade B periodontitis(n=23) ve Grade C
periodontitis (n=19) grubuna dahil edilen bireylerin sondlama cep
derinliği(SCD), klinik ataçman seviyesi(KAS), plak indeks(Pİ), gingival
indeks(Gİ), sondlamada kanama yüzdesi(SKY) gibi klinik kayıtlarının alınmasını
takiben tükürük ve dişeti oluğu sıvısı(DOS) örnekleri toplandı. Del-1 ve LFA-1
sitokin seviyeleri ELISA yöntemi ile değerlendirildi. İstatistiksel analiz için
gruplar arası karşılaştırmalarda Mann-Whitney U testi kullanıldı.p<0.05
istatistiksel anlamlılık düzeyi olarak belirlendi.Bulgular::Klinik parametreler değerlendirildiğinde; SCD, Pİ ve SKY değerleri
anlamlı şekilde, KAS ve Gİ değerlerinin anlamlı olmaksızın Grade C periodontitis
grubunda yüksek olduğu görüldü.ELISA analizleri sonucu LFA-1 ve Del-1 tükürük
ve DOS seviyelerinde gruplar arasında anlamlı fark izlenmedi.Proenflamatuvar LFA-1
tükürük ve DOS seviyelerinin, görece daha şiddetli periodontal hastalığa sahip
bireylerin bulunduğu Grade C grubunda daha yüksek olma eğiliminde olduğu
görüldü.LFA-1 antogonisti olarak bilinen Del-1 tükürük seviyelerinin Grade
B grubunda, DOS Del-1 seviyelerinin ise Grade C grubunda yüksek olma
eğilimi olduğu tespit edildi.Sonuçlar:Bu çalışma ile, nötrofillerin transendotelyal
migrasyonunda rol oynayan Del-1 ve LFA-1 sitokin düzeylerinin periodontal
hastalık şiddeti ile ilgili bilgi verebileceği ancak bu sitokinlerin
periodontal hastalıktaki rollerinin kesin olarak belirlenebilmeleri için ileri
çalışmalara ihtiyaç olduğu görülmektedir.Anahtar Kelimeler:Dişeti
Oluğu Sıvısı,Periodontitis, Sitokin, Tükürük
Çocuklarda Genel Anestezi Altında Uygulanan Diş Tedavileri ile İlgili YouTube™ Videolarının İçerik Analizi
Authors: ÖZTÜRK Gülce , GÜMÜŞ Hüsniye
Published: April 2021

Amaç: Bu çalışmada YouTubeTM platformunda bulunan çocuklarda genel anestezi altında diş tedavisi ile ilgili videoların bilgi içeriği kalitelerini değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: YouTubeTM video paylaşım sitesine “çocuklarda genel anestezi altında diş tedavisi” ve “genel anestezi altında diş tedavisi” terimleri girilerek tarama yapılmıştır. Arama sonucunda 113 video olduğu belirlenmiş ve hariç tutma kriterleri uygulandıktan sonra toplam 24 video değerlendirmeye alınmıştır. Her bir video tek bir araştırmacı tarafından izlenmiş ve bu videolara ait izlenme, beğenilme, beğenilmeme ve yorum sayıları, videonun süresi (dakika), videonun yüklendiği tarihten beri geçen gün ve video kaynağı bilgileri kaydedilmiştir. Video içerik kalitesinin sınıflandırılabilmesi için 8 parametreden oluşan bir puanlama sistemi kullanılmıştır. İstatistiksel değerlendirme için Kruskall Wallis testi, Mann-Whitney U testi ve Spearman korelasyon analizi kullanılmıştır. İstatistiksel anlamlılık değeri p<0,05 olarak alınmıştır.
Bulgular: YouTubeTM platformunda yer alan çocuklarda genel anestezi altında diş tedavisi ile ilgili videoların 3412.83 ± 6082.48 defa izlendiği, 10.13 ± 14.38 defa beğenildiği, 0.96 ± 1.93 defa beğenilmediği ve bu videolara 3.79 ± 9.81 adet yorum yapıldığı belirlenmiştir. Tüm videolardan 11’inin zayıf kalitede bilgi içeriğine, 10’unun orta kalitede bilgi içeriğine ve 3’ünün iyi kalitede bilgi içeriğine sahip olduğu belirlenmiştir. İyi kalitede bilgi içeriğine sahip videoların video süresinin, beğenilme sayısının, izlenme oranı ve bilginin güvenilirliği skorlarının kötü kalitede bilgi içeriğine sahip videolardan anlamlı derecede yüksek olduğu (p<0,05) ancak orta kalitede bilgi içeriğine sahip videolar ile aralarında anlamlı farklılık olmadığı belirlenmiştir (p>0,05).
Sonuç: Çocuklarda genel anestezi altında diş tedavisi ile ilgili YouTube ™ platformunda yer alan videolar bilgi sağlama yönünden yetersizdir. Bu nedenle hekimler ebeveynleri doğru ve güncel bilgileri edinebilmeleri için uygun ve profesyonel kaynaklara yönlendirmelidir.
El buen vivir y la inclusión: Una reflexión desde la legislación educativa ecuatoriana
Authors: Chamorro-Pinchao Christian Xavier , Loor-Cedeño Genesis Noemi , Agreda-Gómez Julia Stefanía
Published: April 2021

El presente artículo pretende reflexionar sobre la concordancia entre el las concepciones del buen vivir, la inclusión y la legislación educativa ecuatoriana, en los planteamientos generales del currículo 2016. La relevancia del trabajo radica en que el currículo ecuatoriano del 2016 guía la formación de las personas que habitan en la sociedad, en razón de lo cual es importante analizar su alineación con el buen vivir, como paradigma de desarrollo constitucional y con los principios de la inclusión, como garante de equidad social. Como proceso metodológico, se realiza una revisión documental que contempla el periodo 2008-2016, expuesta en tres epígrafes: Aproximación al buen vivir desde el Ecuador, fundamentos de la inclusión educativa, y revisión del currículo ecuatoriano desde el buen vivir y la inclusión. Como resultados surge que, en el componente armonía interna, el currículo ecuatoriano aborda, desde lo didáctico y metodológico, el desarrollo del estudiantado como un ser integral; en el componente armonía social no se conceptualiza, dentro del currículo, el respeto de una manera concreta y como bien básico del ser humano; y, el componente de armonía con la naturaleza no se apoya en acciones concretas que permitan su desarrollo dentro del currículo. Se concluye que el currículo ecuatoriano refleja esa pretensión de transformar la sociedad; no obstante, no se proponen acciones concretas para alcanzar una educación inclusiva, concordante con las dimensiones analizadas del buen vivir. Por lo tanto, es necesario un plan de acciones viables que aporten al proceso de construcción de una educación inclusiva, concordante con el buen vivir.
Propuesta de una técnica de comprobación de objetivos de aprendizaje para unidades didácticas mediante el uso de software
Authors: Poltronieri-Méndez Sarita , Garita-González Gabriela
Published: April 2021

Objetivo. El estudio tiene el objeto de proponer una técnica de revisión para la comprobación de los objetivos de aprendizaje en la unidad didáctica, en contraste con la propuesta curricular de la asignatura de la Universidad Estatal a Distancia (UNED, Costa Rica). Metodología. Presenta un enfoque mixto, que hace uso de dos herramientas principales la sistematización de la experiencia por el orden en que sucedió y el grupo focal con 14 personas expertas (11 mujeres y 4 hombres) que realizaron un análisis de confiabilidad del diseño propuesto. Análisis de resultados. El principal hallazgo fue la validación de una técnica de revisión que apoya el proceso de producción de una unidad didáctica. Esta consiste en un proceso de seis pasos que emplea, entre ellos, una rúbrica de evaluación e indicadores, que permiten reflejar el resultado final en un porcentaje de comprobación del desarrollo de los objetivos de aprendizaje de una asignatura en una unidad didáctica. Conclusión. Es posible transformar un proceso, habitualmente, manual a una forma semi automatizada por la incorporación del paquete informático Microsoft® Office Excel, que facilita una comprobación parcial o total de los objetivos desarrollados en la UD y contribuye a la estandarización de procesos actuales.
Jóvenes y elecciones democráticas. Una investigación-acción cogenerativa con un grupo de estudiantes de secundaria
Authors: Salinas-Valdés Juan José , Torres-Lillo Benjamín , Tapia-Henríquez Mario
Published: April 2021

Este artículo presenta los resultados de una investigación-acción cogenerativa, cuyo objetivo de indagación fue valorar un módulo didáctico diseñado a partir de la elección presidencial chilena de 2017, el cual estuvo destinado al desarrollo de competencias ciudadanas y al incentivo de las expectativas de participación electoral futura en jóvenes de secundaria. Para llevarla adelante, se estableció una asociación colaborativa entre el equipo investigador profesional y un docente del sistema escolar, según los planteamientos de Greenwood y Levin. En concreto, veintinueve estudiantes indagaron y debatieron durante cuatro semanas en torno a las propuestas de los diversos candidatos y candidatas, así como respecto a las cuestiones socialmente vivas asociadas a ellas. Posteriormente, se exploró en sus ideas sobre las actividades realizadas, mediante cuestionarios, entrevistas semiestructuradas y un grupo de discusión. Complementariamente, se realizaron observaciones de clases y se entrevistó al docente. Tras ello, la información obtenida fue tratada a partir del método de análisis cualitativo de contenido. Los resultados apuntan a la eficacia del módulo implementado en el desarrollo de competencias ciudadanas y a una alta valoración del estudiantado respecto a la discusión de la realidad social en clases en un ambiente de respeto por las diversas opiniones. Por su parte, las conclusiones establecen una serie de fortalezas y debilidades a tener en cuenta en sus futuras aplicaciones. Asimismo, destacan el rol activo del alumnado y la importancia de debatir cuestiones socialmente vivas en la formación ciudadana, por lo que se sugiere considerar tales elementos en la nueva asignatura chilena de ciudadanía.
Effect of metal concentration on growth and luminescence of luminous bacteria strains isolated from golfo de Nicoya, Costa Rica
Authors: Vega-Corrales Luis , Marín-Vindas Carolina
Published: April 2021

Luminescence in bacteria is catalyzed by luciferase. When these microorganisms are exposed to toxic substances, the bioluminescent enzyme system can be inhibited. The objective of this study was to analyze the potential that these microorganisms offer as native bioindicators of coastal marine pollution. The dynamics of luminescence intensity by visual classification and the effect of metal concentration on the growth and luminescence of 25 strains of luminescent bacteria, isolated during 2016 from seawater samples from the gulf of Nicoya, Costa Rica, was evaluated by the disk diffusion method. The sensitivity of each strain to different concentrations (0.1, 0.5 and 1 mg mL-1) of Cd, Cu, Cr, Pb and Zn was determined by its bioluminescent phenotype. In susceptible strains, a range of metal concentrations less than the growth inhibitory concentration affected the expression of luminescence. Strains with intense luminescence and defined zones of luminescence inhibition were considered to have greater potential as native bioindicators for monitoring environmental toxicity. More studies are required to determine the minimum concentrations that inhibit growth and luminescence with respect to the tested metals and other potentially toxic substances for the coastal marine ecosystems of Costa Rica.
A Health-Literacy Intervention for Early Childhood Obesity Prevention: A Cluster-Randomized Controlled Trial
Authors: Sanders Lee M. , Perrin Eliana M. , Yin H. Shonna , Delamater Alan M. , Flower Kori B. , Bian Aihua , Schildcrout Jonathan S. , Rothman Russell L. ,   Greenlight Study Team
Published: April 2021

BACKGROUND AND OBJECTIVES:

Children who become overweight by age 2 have greater risk of long-term obesity and health problems. The study aim was to assess the effectiveness of a primary care–based intervention on the prevalence of overweight at age 24 months.

METHODS:

In a cluster-randomized trial, sites were randomly assigned to the Greenlight intervention or an attention-control arm. Across 4 pediatric residency clinics, we enrolled infant–caregiver dyads at the 2-month well-child visit. Inclusion criteria included parent English- or Spanish-speaking and birth weight ≥1500 g. Designed with health-literacy principles, the intervention included a parent toolkit at each well-child visit, augmented by provider training in clear-health communication. The primary outcome was proportion of children overweight (BMI ≥85th percentile) at age 24 months. Secondary outcomes included weight status (BMI z score).

RESULTS:

A total of 459 intervention and 406 control dyads were enrolled. In total, 49% of all children were overweight at 24 months. Adjusted odds for overweight at 24 months (treatment versus control) was 1.02 (95% confidence interval [CI]: 0.63 to 1.64). Adjusted mean BMI z score differences (treatment minus control) were −0.04 (95% CI: −0.07 to −0.01), −0.09 (95% CI: −0.14 to −0.03), −0.19 (−0.33 to −0.05), −0.20 (−0.36 to −0.03), −0.16 (95% CI: −0.34 to 0.01), and 0.00 (95% CI −0.21 to 0.21) at 4, 6, 12, 15, 18, and 24 months, respectively.

CONCLUSIONS:

The intervention resulted in less weight gain through age 18 months, which was not sustained through 24 months. Clinic-based interventions may be beneficial for early weight gain, but greater intervention intensity may be needed to maintain positive effects.
Two new species of Octomeria (Pleurothallidinae) from Cordillera del Cóndor, Zamora Chichinpe, Ecuador
Authors: Vélez-Abarca Leisberth , Jiménez Marco M. , Baquero Luis E.
Published: April 2021

Two new species of orchids, Octomeria pacii, and O. panguiensis are described and illustrated from Cordillera del Cóndor, Ecuador; likewise, information is provided on their distribution, habitat, and conservation status. These species differ from other species in the genus by their floral and vegetative characteristics and their apparent reproductive strategy of cleistogamy. Octomeria pacii is similar to Octomeria deceptrix, but differs in the caespitose habit, the ramicauls compressed along their entire length, the narrowly elliptical leaves, the autogamous flowers, the translucent white sepals suffused with magenta and the obovate, white lip, marked with magenta. Octomeria panguiensisis similar to O. werneri, but differs by the larger, shortly repent plants with lanceolate leaves, the cleistogamous flowers, the translucent white-colored sepals, the 5-veined lateral sepals and the oblong-trilobed lip with the apical lobe tridentate

Keywords: self-compatibility, self-pollination, cleistogamy, Octomeria deceptrix, Octomeria werneri
Contrasting metamorphic and post-metamorphic evolutions within the Algyő basement high (Tisza Mega-unit, SE Hungary). Consequences for structural history
Authors: Kondor Henrietta , M Tóth Tivadar
Published: April 2021

The Algyő High (AH) is an elevated crystalline block in southeastern Hungary covered by thick Neogene sediments. Although productive hydrocarbon reservoirs are found in these Neogene sequences, numerous fractured reservoirs also occur in the pre-Neogene basement of the Pannonian Basin. Based on these analogies, the rock body of the AH might also play a key role in fluid storage and migration; however, its structure and therefore the reservoir potential is little known. Based on a comprehensive petrologic study in conjunction with analysis of the spatial position of the major lithologies, the AH is considered to have been assembled from blocks with different petrographic features and metamorphic history. The most common lithologies of garnet-kyanite gneiss and mica schist associated with garnetiferous amphibolite are dominant in the northwestern and southeastern parts of the AH. The first regional amphibolite facies metamorphism of the gneiss and mica schist was overprinted by a contact metamorphic (metasomatic) event during decompression in the stability field of kyanite. Garnet-bearing amphibolite experienced amphibolite facies peak conditions comparable with the host gneiss. Regarding the similarities in petrologic features, the northwestern and southeastern parts of the area represent disaggregated blocks of the same rock body. The central part of the AH area is characterized by an epidote gneiss-dominated block metamorphosed along with a greenschist-facies retrograde pathway as well as a chlorite schist-dominated block formed by greenschist-facies progressive metamorphism. The independent evolution of these two blocks is further confirmed by the presence of a propylitic overprint in the chlorite schists. The different metamorphic blocks of the northwestern, southeastern and central parts of the AH probably became juxtaposed along post-metamorphic normal faults developed due to extensional processes. The supposed brittle structural boundaries between the blocks could have provided hydrocarbon migration pathways from the adjacent over-pressured sub-basins, or could even represent suitable reservoirs.
Dry matter, protein, and energy digestibility of diets for juvenile Pacific white leg shrimps (Litopenaeus vannamei) reared at different salinity levels
Authors: Méndez-Martínez Yuniel , Gucić Milena , Martínez-Córdova Luis Rafael , Civera-Cerecedo Roberto , Ricque-Marie Denis , Cortés-Jacinto Edilmar
Published: April 2021

ABSTRACT: This study evaluated the effect of low, medium, and high-water salinity (5, 35, and 50 ppt) on the apparent dry matter, protein, and energy digestibility of two formulated and six commercial diets for juvenile whiteleg shrimp, Litopenaeus vannamei, in a 120-day trial. Digestibility was determined in vivo using chromic oxide as an inert diet marker. Hydrostability in pellets varied from 86.8% to 99.9%; dry matter digestibility varied from 49.1% to 64.1%; protein digestibility showed greater variations at all salinities (56.9%-85.8%); and energy digestibility ranged from 70.1 to 86.4%. Salinity had a significant effect on dry matter, protein, and energy digestibility. Using a principal component analysis (PCA) with a covariance matrix, our findings suggested that the E2 (fishmeal-based formulation) diet and 35 ppt salinity provided optimum hydrostability and digestibility to Pacific white leg shrimp juveniles.
Interaction of acetyl-CoA carboxylase enzyme inhibiting herbicides with auxin herbicides on ryegrass
Authors: Polito Rubens Antonio , Pasqualotto Larissa , Dysarz Rafael , Cinelli Rafaela , Heck Tamara , Nunes Anderson Luis
Published: April 2021

ABSTRACT: This study aimed to evaluate the antagonistic effect of the mixture ofacetyl coenzyme-A carboxylase (ACCase) enzyme inhibiting herbicides and auxin herbicides in Lolium multiflorum and to determine mechanisms to mitigate this possible effect. The first experiments were conducted by associating the herbicide clethodim (108 g a.i. ha−1), quizalofop-p-ethyl (54 g a.i. ha−1), and clethodim + quizalofop-p-ethyl (108+54 g a.i. ha−1) with 2,4-D (1005 g a.e. ha−1) or triclopyr (720 g a.e. ha−1), in addition to the sole application of the respective graminicides. Another experiment included clethodim (54; 81; 108; 162; 216 g a.i. ha−1), quizalofop-p-ethyl (27; 40.5; 54; 81; 108 g a.i. ha−1), and clethodim + quizalofop-p-ethyl (54+27; 81+40.5; 108+54; 162+81; 216+108 g a.i. ha−1) mixed with 2,4-D (1005 g a.e. ha−1), or triclopyr (720 g a.e. ha−1), in addition to the control treatments without herbicide application. In the second experiment, herbicides clethodim (108 g a.i. ha−1), quizalofop-p-ethyl (54 g a.i. ha−1), and clethodim + quizalofop-p-ethyl (108+54 g a.i. ha−1) in combination with the herbicides 2,4-D (1005 g a.e. ha−1) or triclopyr (720 g a.e. ha−1)had malathion (1000 g a.i. ha−1) or glyphosate (720 g a.e. ha−1) mixed, in addition to the sole applications of the graminicides. The herbicide clethodim + quizalofop-p-ethyl did not present an antagonistic interaction with the auxin herbicides, and obtained 85% weed control. To obtain control similar to the sole application of this graminicide, the dose of the herbicide clethodim needs to be increased by 20%. However, the mixture of the herbicide quizalofop-p-ethyl with 2,4-D and triclopyr affects the ryegrass control. The use of strategies that increase the absorption of ACCase herbicides or the inhibition of P450 enzymes are ways to mitigate the antagonistic effect caused by the association of the two auxin herbicides.
Ideal temperature and storage period for commercial potato cultivars selected for frying
Authors: Cruz Renata Ranielly Pedroza , Pereira Ariana Mota , Ribeiro Wellington Souto , Freire Ana Izabella , Costa Franciscleudo Bezerra da , Zanuncio José Cola , Finger Fernando Luiz
Published: April 2021

ABSTRACT: Potatoes for industrial processing must have high dry matter, low sugar and free from damage or disease. The objective was to determine the ideal temperature and storage period of commercial cultivars for frying. Tubers of Asterix and Cronos cultivars were stored in a cold chamber (Gallant CMC4 Premium) inside plastic boxes at 6 and 8 °C with 85 to 95% humidity for 180 days. Accumulated mass loss (PMA), alcohol insoluble solids (SIA), total soluble sugars (AST), non-reducing sugars (ANR), reducing sugars (AR), polyphenoloxidase activity (PPO) and enzymatic and non-enzymatic browning were analyzed. The PMA of Asterix at 6 and 8 ºC and Cronos at 6 °C was higher. The SIA of both cultivars stored at 6 ºC were lower and AST, AR and ANR higher. Those parameters of Cronos and Asterix did not differ between temperature or storage period. The browning was greater in the fried sticks of Asterix and Cronos stored at 6 ºC (4 to 5) for 60 and 90 days and at 8 °C (2 to 3) for 180 days, respectively. The ideal temperature and storage period for Asterix and Cronos cultivars is 8 ºC for a maximum of 120 days due to non-enzymatic browning.
O paradigma indiciário para análise de narrativas
Authors: Leandro Everaldo Gomes , Passos Cármen Lúcia Brancaglion
Published: April 2021

RESUMO Neste artigo objetiva-se apresentar contribuições do paradigma indiciário para a análise de narrativas em pesquisas do campo da Educação. O paradigma indiciário, estudado e utilizado pelo historiador italiano Carlo Ginzburg, possibilita interpretar a realidade, algumas vezes opaca, em busca de características menos vistosas, de indícios que permitam decifrá-la e compreendê-la. Porém, constatou-se que há uma utilização restrita do paradigma indiciário no Brasil, e por esse motivo surgiram perguntas: que contribuições o paradigma indiciário traz para a análise de narrativas? E que elementos considerar, à procura de indícios? Esta pesquisa é de cunho teórico e constitui-se como um recorte da tese de doutorado do primeiro autor.
Memoriais e narrativas na formação de educadores da saúde: escritas de si, acompanhamento e mediação biográfica
Authors: Reis Alessandra Martins dos , Souza Elizeu Clementino de
Published: April 2021

RESUMO As narrativas de educadores da saúde configuram-se como dispositivo que favorece a compreensão de aprendizagens experienciais no espaço formativo da Pós-Graduação em Educação na Saúde. Seu contexto de inserção são as Residências em Saúde, espaços de formação que integram o ensino e os serviços do Sistema Único de Saúde (SUS) no Brasil. Ancorados em princípios da pesquisa (auto)biográfica e na utilização de memoriais, objetiva-se discutir questões relacionadas ao processo de acompanhamento, suas interfaces com as escritas de si e as disposições de investigação-formação mobilizadas pela escrita de memoriais de três educadores no campo da formação em saúde, na condição de preceptores no Programa de Residências da Fundação Estatal Saúde da Família (FESF-SUS) na Bahia. As experiências de cuidado e de educação em equipes multiprofissionais são colocadas em reflexão nos memoriais de formação de educadores da saúde como processo de mediação do vivido e das relações entre formador e formandos, por meio das narrativas de experiências, com ênfase no desenvolvimento pessoal e profissional no contexto da formação em saúde.
Biografia e temporalidades: prática historiográfica e o ensino de história
Authors: Cardoso Michele Gonçalves
Published: April 2021

RESUMO O presente artigo tem como objetivo propor reflexões sobre a escrita biográfica e seus tensionamentos com o campo da pesquisa/ensino de história. Compreendendo que o empreendimento biográfico é resultado de uma escrita fundamentalmente atravessada por temporalidades diversas, percebemos na artificialidade dessa escrita sua potencialidade para analisarmos os descontínuos da vida humana e suas relações no tempo/espaço. Deste modo, buscamos destacar importantes aspectos do diálogo entre história e biografia, evidenciando novos aportes teóricos e metodológicos que contribuem, ainda, para a revisitação de seu uso e de sua produção para o ensino de história.
A abordagem “Histórias de vida em formação” como superação da dupla armadilha do conceito sem vida e da vida sem conceito
Authors: Lainé Alex
Published: April 2021

RESUMO Este artigo pretende mostrar como realizar um processo eminentemente formativo, fundamentado em uma prática concreta de histórias de vida em grupo num contexto de formação. Por esses termos entendemos um processo por meio do qual cada narrador engaja-se em algo que lhe auto represente e que se transforma com vistas a aumentar o seu poder de aprender. Em paralelo, a visão de cada participante sobre o seu ambiente é modificada. As condições éticas, deontológicas e metodológicas necessárias para este tipo de trabalho são especificadas ao mesmo tempo em que o autor sublinha a importância da dialética que se desdobra entre a implicação individual de cada participante e o coletivo.
Massive thrombosis and phlegmasia cerulea dolens while taking rivaroxaban: case report and review
Authors: Chemello Diego , Rosa Larissa , Araujo Amanda Faria de , Araujo Pedro Cargnelutti de , Pereira Luiz Carlos Carneiro , Hillesheim Suélen Feijó , Saffi Marco Aurélio Lumertz
Published: April 2021

Abstract Our study describes a fatal case of phlegmasia cerulea dolens and massive venous thrombosis in a patient taking rivaroxaban regularly to treat cerebral venous sinus thrombosis. Blood tests samples were positive for lupus anticoagulant. The unique evolution of the case, as well as the positivity for lupus anticoagulant, raises the possibility of an acquired hypercoagulation syndrome. We highlight the fact that the test recommended as the first line for lupus anticoagulant diagnosis (dilute Russell viper venom time) is the most affected by rivaroxaban, leading to a high prevalence of false-positive results. We also discuss potential diagnoses for the current case and review the current state-of-the-art of use of the novel oral anticoagulation agents in this unusual situation. So far, there are no recommendations to use such agents as first options in cerebral venous sinus thrombosis or in hypercoagulation syndromes.
Repercussão da doença arterial periférica na tolerância ao exercício e na qualidade de vida de idosos e o papel da fisioterapia cardiovascular: artigo de revisão
Authors: Lourenço Ana Leticia Gonçalves , Silva Josicléia Leôncio da , Leite Jéssica Costa
Published: April 2021

Resumo A doença arterial periférica tem como principal sintoma a claudicação intermitente, fator que resulta em incapacidade funcional, comprometendo a qualidade de vida. Esta revisão objetivou fazer um levantamento sobre os impactos ocasionado pela doença nos idosos, investigando as possíveis contribuições da fisioterapia cardiovascular. Para isso, realizou-se uma busca nas bases de dados MEDLINE, LILACS, SciELO, Scopus, Science Direct e PEDro, a qual identificou 7.587 estudos. Desses, sete atenderam aos critérios de elegibilidade, sendo então agrupados e analisados conforme o nível de evidência, grau de recomendação e qualidade metodológica. Pôde-se observar um considerável impacto da doença sobre a tolerância ao exercício e a qualidade de vida. Quanto à abordagem terapêutica desses desfechos, os estudos relataram que houve melhora na deambulação e na qualidade de vida, aumento da capacidade funcional e redução da dor. No que se refere à modalidade de tratamento, a maioria das pesquisas incluíram exercícios aeróbicos.
Fatores associados ao enfrentamento da pandemia da COVID-19 por pessoas idosas com comorbidades
Authors: Souza Filho Zilmar Augusto de , Nemer Camila Rodrigues Barbosa , Teixeira Elizabeth , Neves André Luiz Machado das , Nascimento Marcia Helena Machado , Medeiros Horacio Pires , Panarra Bruna Alessandra Costa e Silva , Lima Paula Andreza Viana , Gigante Vanessa Calmont Gusmão , Oliveira Vera Lúcia Gomes de
Published: April 2021

Resumo Objetivo identificar fatores associados ao enfrentamento da pandemia da COVID-19 por pessoas idosas com e sem comorbidades. Método estudo descritivo, transversal, com pessoas idosas (n=569), entre 60 e 80 anos, com ou sem comorbidades, nas cinco regiões do Brasil. Coleta de dados com questionário virtual e análise com base na estatística descritiva e inferencial. Resultados os resultados mostram que 351, (61,68%), referem comorbidade. Houve associação significativa entre os grupos nas variáveis: faixa etária (p=0,017), realizar alguma atividade laboral (p≤0,001), pensamento da possibilidade de ser infectado pelo novo coronavírus (p≤0,001), concordar com medidas de prevenção adotadas para o distanciamento social (p≤0,001), se informar por outro meio de comunicação além da televisão (p≤0,001). Conclusão e implicações para a prática os idosos com comorbidades pensam na possibilidade de ser infectado pelo novo coronavírus, concordam mais com as medidas de distanciamento social e se informam mais. Nesse sentido, indica-se a realização de pesquisas com ênfase nos idosos sem comorbidade, para direcionar melhor os cuidados de saúde em tempos de pandemias.