bluuebunny/crossref_metadata_2025 huggingface dataset:
Alterações Neuropsicológicas no Transtorno Bipolar
Authors: Assunção Izabely Lima , Coelho Déborah Calado , Meinertz Eduarda Felipe , Costa Fábio Mendonça da , Regadas Mariana Silva , Carreiro Matheus , Dias Maria Teresa , Salomão Vitor Palmeira , Tramontin Ingrid Monteiro , Farias Luan Pinho , Rodrigues Júlia Barbosa , Nascimento Andressa Barros de Sousa , Castro Kaline dos Santos Kishishita , Gonçalo Sarah Mota , Britto Maria Fernanda de Lima , Vale Raíssa Thaynana Torres
Published: June 2022

O transtorno bipolar (TB) é uma das patologias psiquiátricas consideradas mais graves, e com uma taxa alta de suicídio entre os portadores. Os sintomas podem variar de leves a graves de acordo com o tipo de transtorno bipolar, seja ele tipo I ou II. O Objetivo desta revisão sistemática é levantar dados e informações a respeito das alterações que o TB causa na vida das pessoas que possuem essa patologia.  A metodologia utilizada para o levantamento dos dados, foram a pesquisa de artigos em bases de dados como Pubmed, Scielo, e Google Acadêmico, compreendendo os anos de 2015 a 2022. Os resultados encontrados foram unânimes em relação às consequências e danos que o TB causa aos portadores, dentre eles, a influência sobre as funções cognitivas, e comportamentais dos indivíduos, desde a fase infantil. Podemos concluir que os achados dessa revisão contribuem e servem como um suporte para o conhecimento e conscientização sobre a importância do diagnóstico precoce e possíveis tratamentos, para que os sintomas sejam amenizados, e consequentemente o sofrimento dos portadores também.
Os desafios do microempreendedor: uma análise pós pandemia do Covid-19
Authors: Santos Aline Batista dos , Santos Camila Silva Evangelista dos , Costa Denis Honorato
Published: June 2022

Este artigo refere-se aos desafios enfrentados durante o período de pandemia que estamos vivenciando no mundo e os impactos gerados na vida das micro e pequenas empresas. O ano de 2020 marcou a história da humanidade com o surgimento de um dos piores eventos que atingiu o mundo e afetou negativamente a economia inclusive no Brasil. A pandemia provocada pelo Coronavírus (Covid-19), obrigando diversos setores da economia a se reinventarem, diante dos inúmeros desafios impostos pelas consequências do vírus em toda cadeia produtiva e consumidora, levando-os a inovação ou até mesmo falência. O objetivo é discutir estratégias através das limitações impostas pelo isolamento social. Para composição desta revisão da literatura, foram realizadas busca entre fevereiro a maio, por material científico relacionado as principais Bases de Administração, por meio de bases de dados como: Google Acadêmico. Foram selecionados artigos e livros com texto disponível na íntegra que tivessem relação com o tema proposto, escritos em português, em consulta às bases metodológicas administrativas, com base trabalhos publicados nos últimos 02 anos. Inicialmente foram listados em torno de 7.130 resultados de artigos com as respectivas palavras-chaves: Pandemia da Covid-19; Dificuldades financeiras; Microempreendedores. Onde 16 destes foram escolhidos aleatoriamente, mas que estivessem diretamente ligados ao tema deste trabalho. Consideramos que as estratégias de marketing digital se consolidam como uma realidade no mercado atual, configurando-se como meio rápido, barato e eficaz de empresas com menor grau de investimento alavancarem seus faturamentos. Ou seja, o avanço tecnológico continua sendo a melhor alternativa para os empreendedores.
Liderança e o impacto da saúde mental no clima organizacional
Authors: Oliveira Priscila Tomé de , Ferreira Priscilla Tavares , Costa Denis Honorato
Published: June 2022

Alta porcentagem de profissionais não tem suporte voltado à saúde mental, o que influencia a pessoa humana, causando o afastamento de colaboradores, contudo, a ausência de motivação traz sensação de inércia profissional, pois o clima organizacional impacta a saúde emocional dos indivíduos. Um líder deve ter a habilidade de motivar pessoas de forma positiva, ser capaz de separar a emoção de todas as interações e regular os ânimos da equipe. Apresentar o clima organizacional de uma empresa com objetivo de proporcionar experiências positivas com base em aspectos motivacionais, evitando assim o absenteísmo, incentivando o desenvolvimento pessoal para que com resiliência e motivação possa exercer sua função sem que desenvolva síndromes e/ou abalos psicológicos. Para composição desta revisão da literatura, foram realizadas busca entre fevereiro a maio, por material científico relacionado a liderança e o impacto da saúde mental no clima organizacional, por meio de bases de dados como: Pubmed e Google Acadêmico. Foram selecionados artigos e livros com texto disponível na íntegra que tivessem relação com o tema proposto, escritos em português ou inglês, em consulta às bases metodológicas de dados em administração de empresas. Após leitura dos resumos, 24 artigos foram selecionados, para compor o corpo estrutural dessa revisão. Um colaborador que obtém reconhecimento, motivação e uma boa liderança, é capacitado de resiliência e flexibilidade para lidar com situações estressantes, transições e crises, e assim estar hábil a empenhar-se mais no seu trabalho para obter o crescimento pessoal e profissional, gerando assim benefício para empresa e bem-estar ao colaborador.
Perfil microbiano em resposta a implementação de plano de capacidade plena na unidade referência de tratamento de queimados em Sergipe
Authors: Santos Larissa Sá dos , Rodrigues Mariana de Vasconcelos Barreto , Costa Rômulo Carvalho , Silva Francisca Roberta Oliveira , Santos Beatriz Oliveira , Oliveira Rosa Carolina Santos de , Câmara Ana Cláudia de Brito , Cintra Bruno Barreto
Published: June 2022

Objetivo: O estudo tem como objetivo descrever o perfil microbiano dos internos em Unidade de Tratamento de Queimados (UTQ) do Hospital de Urgência de Sergipe (HUSE) em resposta à implementação do Plano de Capacidade Plena (PCP) entre novembro de 2021 e março de 2022 em comparação com o apresentado pela mesma unidade de janeiro de 2020 a outubro de 2021, quando não haviam pacientes PCP. Método: Trata-se de um estudo retrospectivo, descritivo, com abordagem quantitativa, sendo realizada a análise de dados através dos prontuários existentes na UTQ do HUSE, com foco no perfil de infecção microbiana dos pacientes internados no período de novembro de 2021 e março de 2022. Resultados: Foram avaliados 298 prontuários, sendo 290 provenientes de pacientes queimados e 8 de pacientes não queimados remanejados para a unidade. Desses, foram feitas 47 coletas de culturas, com presença de 43 bactérias (91,5%) e 4 fungos (8,5%). No comparativo entre os dois grupos estudados, o microrganismo mais prevalente no período sem o PCP foi a Acinetobacter baumannii complex (38,2%) e a Stenotrophomonas maltophilia prevaleceu (30,8%) no grupo exposto por 5 meses ao plano, destacando-se a detecção de fungos como Candida tropicalis (7,7%) e Trichosposon asahii (7,7%) Conclusão: Apesar de se tratar de um estudo com amostragem baixa, é possível perceber uma mudança de padrão no perfil microbiano da unidade, abrindo espaço para bactérias e fungos oportunistas mais resistentes aos antibióticos tradicionalmente utilizados na unidade.
Infraestructura econômica e probabilidade de probreza na Paraguai
Authors: Cuenca López Anibal David , Camargos Teixeira Evandro
Published: June 2022

O objetivo deste estudo é analisar o efeito do acesso à infraestrutura econômica sobre a probabilidade de os indivíduos estarem abaixo da linha de pobreza no Pa-raguai em 2018. Para tal, foi estimado um modelo logístico ordenado multinível em dois níveis, individual e departamental. Os resultados indicam que o acesso aos serviços de infraestrutura econômica é primordial para a diminuição da probabili-dade de pobreza no Paraguai. Por conseguinte, denota-se a importância da elevação dos investimentos em infraestrutura, sejam públicos ou privados, com o intuito de elevar a qualidade de vida dos cidadãos paraguaios.
Exploring the duration of exports: evidence from Cote d'Ivore
Authors: Brice Adou Niango Sika Antoine , Socrates Majune Kraido
Published: June 2022

This paper investigates the effect of urbanization on export duration in Cote d’Ivoire using HS 6-digit level bilateral export data between Cote d’Ivoire and 155 countries from 1996 to 2018. We found that the mean and median duration of exporting in Cote d’Ivoire are 1.8 years and 1 year, respectively. Using a discrete-time logit model with random effects, we established that urbanization in the importing country reduces survival of Ivorian exports, specifically, in Sub-Saharan Africa, and in low- and middle-income countries. Urbanization in Europe and Central Asia and in high-income countries improves survival of Ivorian exports, while the internal urbanization index has not contributed to maintain export duration.
Increasing Complexity: Australia’s foreign policy links with Latin America, 1973 to 2019
Authors: Esposto Alexis , Abbott Malcolm , Tran My
Published: June 2022

This paper provides an analysis of the evolution of engagement and trade between Australia and Latin America. These regions are seen as competitors, but trade and engagement has recently increased. We examined this growth from the 1970s, by analysing trade, foreign direct investment, and migration and tourism flows. This article investigates how both parts of the world have engaged and dealt with international conflicts, either in terms of diplomatic or multilateral cooperation. The paper concludes that there are many possible channels for cooperation and further trade and engagement open to both.
Does export destination matter for the economic growth of Ghana?
Authors: Baidoo Samuel Tawiah , Baajike Franklin Bedakiyiba , Ayesu Enock Kojo , Takyi Paul Owusu
Published: June 2022

This study investigates whether export destination matters for economic growth. This important question is answered by utilising annual time series data spanning the period 1996–2018 on Ghana. Two main export destinations for Ghana – sub-Saharan Africa (SSA) and Europe and Central Asia (ECA) regions are selected for the analysis. The results from the autoregressive distributed lag (ARDL) model show that, export destinations really matter for economic growth. Specifically, exports to the SSA region is not growth enhancing in the long-run, but exports to the ECA region is growth enhancing in both the short- and long-run. Based on the findings, we provide policy suggestions, which seek to improve economic growth through exports for consideration.
Study of diacetyl-water clusters using Raman scattering and theoretical calculations
Authors: Jumabaev А. , Hushvaktov H. , Absanov A. , Norkulov A. , Iltizarov B.
Published: June 2022

In this work, the intermolecular interactions of diacetyl and water molecules were studied using the vibration spectrum. The Raman scattering spectra obtained in the range of 500– 2000 cm−1 were analyzed and compared with the results of calculations. For the first time аlso, the charge density distribution and 3D potential energy graphs are examined using simulations for diacetyl molecules. With the increase in the number of molecules at the formation of molecular clusters with the water molecule, the saturation of the intermolecular interaction energy corresponding to a single Н-bond is observed. This corresponds to DA+(Н2O)3 molecular clusters and allows one to conclude that this cluster is stable relative to the others.
Изучение относительной прочности связи f-, s- и d-электронов редкоземельных лантаноидов
Authors: Эшкабилов Н.Б. , Курбаниязов А.С.
Published: June 2022

Исследованы относительные прочности связи различных электронных конфигураций редкоземельных элементов. Обнаружена общая тенденция упрочнения связи электронов 4f по сравнению со связью электронов 5d. Показано, что, чем больше заряд ядра, тем прочнее связь электронов 4f по сравнению с валентными электронами 5d, обладающими большим главным квантовым числом. Ключевые слова: спектры, редкоземельные элементы, электронные связи, относительная прочность, электронная конфигурация, электронные оболочки, потерянные электроны, энергетическая выгодность.
Влияние γ-облучения на механизм переноса тока в прямой ветви вольтамперной характеристики Al–p-CdTe–Mo структуры
Authors: Ачилов А.С. , Кабулов Р.Р.
Published: June 2022

Рассматривается влияние облучения γ-квантами на механизм переноса тока в структуре Al-p-CdTe-Mo с протяженной базой (w = 120 μm). Показано, что прямая ветвь ВАХ структуры Al-p-CdTe-Mo до и после облучения описывается степенной зависимостью J ~ Vβ с двумя участками: на участке D β = 1.2, a на участке F β = 3.45. Определенная из прямой ветви ВАХ величина удельного сопротивления ρ  2.1×107 Ωcm слоя p-CdTe хорошо соответствует величине удельного сопротивления исходной пленки p-CdTe. Экспериментально наблюдаемый на втором участке (F) прямой ветви ВАХ резкий рост тока также подтверждает, что фронтальный гетеропереход (n+-p-гетеропереход Al-n- Al2O3-p-CdTe) по качеству намного превосходит тыльный гетеропереход (p-n-переход p-CdTe-n-MoO3-Mo).
Получение пленок CoSi2/SiO2/Si(111) методом лазерного напыления и их электрофизические свойства
Authors: Умирзаков Б.Е. , Бекпулатов И.Р. , Игамов Б.Д. , Турапов И.Х. , Фаттахов А.З.
Published: June 2022

В данном исследовании определен оптимальный режим формирования таблетки CoSi2 методом высокотемпературного прессования. Пленку CoSi2/SiO2/Si(111) получали напылением CoSi2 на подложку SiO2/Si(111) под действием твердотельного импульсного лазера. Изучение зависимости энергии поглощенных пленкой фотонов от длины волны падаюших фотонов показало, что ширина запрещенной зоны чувствительна к длинам волн в видимой и ИК-областях. Рентгеноструктурный анализ системы CoSi2/SiO2/Si(111), сформированной при термическом нагреве, показал, что пленка CoSi2 имеет поликристаллическую структуру. Элементный состав и ширину запрешенной зоны пленки CoSi2 различной толщины определяли методом растровой электронной микроскопии. Для пленки CoSi2 толщиной ≈3 монослоев ширина запрещенной зоны составляет ~0.8 эВ, а для массивной пленки CoSi2 ~0.6 эВ.
An analytical study on early kick detection and well control considerations for casing while drilling technology
Authors: Elsayed Said K. , Azab Hany M. , Salem Adel M. ,   Faculty of Petroleum and Mining Engineering, Suez University, Suez 43528, Egypt
Published: June 2022

Casing while drilling (CwD) technology is designed to reduce drilling time and expenses by improving the wellbore stability, fracture gradient, and formation damage while reducing the exposure time. However, for the purpose well control, the wellbore geometry and volumes differ from those obtained via a conventional drilling technique, thereby requiring a different approach. This study discusses well control principles for CwD operations. It presents a simplified method for evaluating the maximum kick tolerance and allowable well shut-in time for both conventional and CwD techniques using a mathematical model. Preliminary results revealed that the use of CwD leads to an annulus pressure loss three times higher than that observed in the conventional drilling. In addition, the kick tolerance is reduced by 50% and the maximum allowable well shut-in time is reduced by 65%, making an early kick detection system necessary.
Exploring the topological effect of linear and cyclic macroCTAs during polymerization-induced self-assembly (PISA)
Authors: Yin Depeng , Xu Wen , Zhang Hualong , Liu Chao , Hong Chunyan ,   CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei 230026, China
Published: June 2022

Polymerization-induced self-assembly (PISA) is a robust strategy for the syntheses of block copolymer nano-objects with various morphologies. Although PISA has been extensively studied, the use of cyclic macromolecular chain transfer agents (macroCTAs) as the hydrophilic block has not been reported. We explored the effects of macroCTA topology on the polymerization kinetics and morphologies of block copolymer assemblies during reversible addition-fragmentation chain transfer (RAFT) dispersion polymerization. To this end, linear and cyclic poly (ethylene oxide) (PEO) with 4-(4-cyanopentanoic acid) dithiobenzoate (CPADB) groups were synthesized and used as CTAs to mediate the RAFT polymerization of benzyl methacrylate (BzMA) and 2,3,4,5,6-pentafluorostyrene (PFSt) under PISA formulation. Interestingly, the nucleation period of the linear PEO is slightly shorter than that of its cyclic analog, and the cyclic hydrophilic segment leads to a delayed morphological transition during PISA.
Acute Generalized Exanthematous Pustulosis;
A Case Report
Authors: Melarosa Putu Resika , Supradnyan Harry
Published: June 2022

Introduction: Acute generalized exanthematous pustulosis (AGEP) is a severe allergic skin reaction associated with substance use. Not all drugs cause an AGEP reaction. The incidence of AGEP is extremely rare compared to other drug allergies. Therefore, correct identification and proper history acquisition are important for the purpose of providing appropriate and prompt treatment to patients, improving good prognosis and reducing mortality.
Case Presentation: A 17 years antique male affected person, got here with leader proceedings of purple spots at the palms and ft observed with the aid of using itching. Red spots seem after the affected person takes the drug. The affected person became given remedy withinside the shape of oral antihistamines, intravenous steroids, and topical steroids. The affected person became discharged from the health center in excellent condition.
Conclusion: Acute Generalized Exanthematous Pustulosis is a skin disorder that is generally caused by drugs and has a good prognosis because it can heal by itself.

Key words: acute generalized exanthematous pustulosis, drug eruption, skin, disease.
Comparative Study Between Instrumental Assisted Soft Tissue Mobilization and Static Stretching on Delayed Onset of Muscle Soreness in Young Adult Female
Authors: Shinde Shrikrishna , Jethwa Ketki , Pawar Devanshi
Published: June 2022

Aim:To compare the effect of IASTM and static stretching on delayed onset muscle soreness in young females.
Objectives:To find out the effectiveness of instrumental assisted soft tissue mobilization on reducing delayed onset of muscle soreness (DOMS). To find out the effectiveness of static stretching on reducing delayed onset of muscle soreness (DOMS). To compare the effectiveness of instrumental assisted soft tissue mobilization and static stretching on reducing delayed onset of muscle soreness (DOMS).
Methodology:In this comparative study, 40 young adult females who fulfilled the inclusion criteria were recruited from MVP’S college and research center.Subjects were then divided into 2 groups: GROUP A: IASTM and GROUP B: Static stretching.
First of all, DOMS was induced in each subject using exercise protocol. Then the treatment was given for the next 3 days. Outcome measures of NPRS, ROM of ankle dorsiflexion and Y balance scale were evaluated before and after each treatment session.
Results:ANOVA was found significant when the data was compared within the groups as well as Unpaired t test was found significant when data was compared between the groups.
Conclusion:This study concluded that IASTM and static stretching both are effective for delayed onset of muscle soreness. It was found that both IASTM and static stretching decreases pain, increase range of motion and balance. Clinically and statistically IASTM was found more effective than static stretching.

Key words: DOMS, IASTM, Static stretching, gastrocnemius, NPRS.
Evaluation And Management of Postoperative and
Post Anesthesia Concerns in Adults
Authors: Babu Sajja Ravindra , Archana Puligari , Sucharith Marka
Published: June 2022

Background: Postoperative effects are problems that can happen after undergoing surgery but which were not intended. The most common postoperative effects include fever, infection, pulmonary embolism, deep vein thrombosis, bleeding etc. Post anesthesia effects are the problems that may occur after injecting anesthesia in the body for temporary loss of sensation or awareness. Effects are treated accordingly with supportive medications.
Objective: To evaluate and mange postoperative and post anesthesia concerns in adults.
Methods: A prospective observational study, which was conducted on 60 postoperative and 80 post anesthesia patients. Data was collected by using a structured data collection from November 2021 to April 2022 and then statistically analyzed.
Result: 60 postoperative and 80 post anesthesia patients were observed. Out of 60 postoperative patients 70% of with co morbid conditions and 30% without comorbid conditions. Patients with comorbid conditions show more effects than patients without comorbid conditions. The group of above 58 years shows 34% postoperative effects and most effected. Out of 80 Post anesthesia patients, 20 were GA, 20 were LA, 20 were RA and 20 were MAC. In this, general anesthesia shows more effects than other anesthesia.
Conclusion: This study indicated that Postoperative effects in patients with comorbid conditions are more than in patients without co morbid conditions above 50 years shows more effects. In post anesthesia effects, general anesthesia shows more effects than regional, regional shows more effects than MAC, MAC shows more effects than local anesthesia. Postoperative and post anesthesia effects are treated with supportive medications.

Key words: Postoperative concerns, Post anesthesia concerns, Management, General anesthesia, Local anesthesia, Regional anesthesia and MAC/Sedation.
Effectiveness of Otago Exercise Versus Task Oriented Progressive Resistance Strength Training on Balance and Functional Performance in Stroke Patients
Authors: Satish Valiv Aishwarya , Bhore Vrushali
Published: June 2022

BACKGROUND: Stroke is one of the main causes of adult disability worldwide and global health problem. Due to ongoing neurological sequelae post stroke patients have a two-fold higher risk of falling than other people with same age or gender. Around 85% of these patients have residual symptoms of paralysis post stroke, which predisposes them for fall. Balance disorders reduces the independence and level of participation in community. As the stroke patients balance is impaired and can lead to complications such as fall, knowing the questions related to balance and gait will be important in order for these two physical capabilities to be better understood in hemiparetic patients. Promising interventions that could be beneficial to improve the aspects of gait include fitness training, high intensity therapy and repetitive task training.
AIM: The aim of this study is to compare the effectiveness of Otago exercise versus Task oriented progressive resistance strength training on balance and functional performance in stroke patients.
METHOD: 30 hemiplegic stroke patients able to ambulate independently will be taken for the study. The subjects were divided in two groups. Pre-test assessment (Berg balance scale, timed up and go test) will be taken. Group A will be given Task oriented progressive resistance strength training with Conventional Physiotherapy and Group b will be given Otago exercise program fifty minutes each session three times per week for 4 weeks. Then post-test assessment (Berg balance scale, timed up and go test) will be taken.
RESULT: Statistical analysis was done within group using paired t test, which showed significant improvement post exercise protocol in both the groups with p value 0.001. Statistical analysis done between the group using unpaired t test, which showed significant improvement in Group B compared to Group A, with the effect size for group A is 4.89 for BBS and 3.24 for TUG and the effect size for group B is 7.47 for BBS and 4.69 for TUG. Which shows Group B is better than Group A.
CONCLUSION: Otago exercise and Task oriented progressive resistance strength training were significant in terms of clinical outcome and both shows equal p- value of 0.001. the effect size of group B for BBS and TUG is more as compared to group A BBS and TUG, which shows group B is more effective.

Key words:Stroke, Otago exercise program, Task oriented progressive resistance strength training, balance, functional performance, BBS, TUG.
Effectiveness of Foam Rolling Versus Static Stretching on Pain, Hip Adduction ROM in ITB Tightness in Athletes
Authors: Raikwar Supriya , Athavale Neeraj
Published: June 2022

Background: Foam rolling is a relatively new technique in improving ranges and reduction in pain so its effectiveness has to be studied.
Study Design: 1week interventional comparison study
Objectives: To assess & compare the pre and post interventional results of a 1week Static Stretching programme in one group versus Foam Rolling programme in other group on ITB tightness in athletes.
Methods: Forty male subjects were enrolled in study out of which forty male subjects (age group 19-25 years) having ITB tightness defined by active hip adduction test, nobles test and Ober’s test were included and randomly assigned to foam rolling and static stretching groups (20each). Active hip adduction, VAS values measurements pre, mid and post-intervention were taken. Foam rolling: Subject did continuous rolling of ITB on the foam roller, from the ischial tuberosity to the lateral knee for 1minute.
Static stretches: For the static stretch the subjects placed their leg behind normal leg with their knee extended and their ankle neutral in standing posture. Subjects were then instructed to lean sideways from the hip, with their spine in neutral until a stretch was felt in the lateral thigh in ROM which were highly significant on analysis
Results: Unpaired t-test for comparison of one week findings of both static stretching and foam rolling group showed significant changes with p=0.00, there is significant variation in mean observed for static stretching and foam rolling
Conclusion: This study revealed that both foam rolling and Static stretching were effective techniques for increasing hip adduction ROM and reducing pain showing improvement but Foam rolling produced more significant results as compared to static stretching group over a week intervention plan

Key words: Myofascial release; active hip adduction; autogenic inhibition; Foam Rolling; Static Stretching .
Evidence of Barriers to Evidence-Based Physiotherapy Practice in Central Africa
Authors: Sharma Krishna Nand
Published: June 2022

Physiotherapists are responsible for assessment, planning, and implementation of rehabilitative programmes. Being part of medical team, it becomes important for them to use research findings in their practice. Evidence-Based-Physiotherapy practice is gaining attention across the globe. However, there are still barriers that hinder its practice. This mini-review explores recorded evidence of barriers to evidence-based-physiotherapy practice in the central African countries.

Key words: Physiotherapy, Research, Barriers, Evidence-Based-Physiotherapy, Evidence-Based-Practice, Central Africa.
Serum Lactate Dehydrogenase: A Possible Metabolomics Biomarker for the Early Detection of Head and Neck Cancer Lymph Node Metastasis
Authors: Meena Pushpa , Sharma Anjali , Meena Dalpat
Published: June 2022

Head and neck cancer (HNC) appears with one of the most recurring sites of cancer, and the percentage of metastases is also high in both localized region and distant areas. Diagnosis of metastases is correlated with poor prognosis, with a median survival of about 10 months. Therefore, early diagnosis is of utmost significance in the treatment of HNC. Metabolomics study targeting altered metabolic pathways exhibits a promising approach for discovering early novel noninvasive targets and biomarkers in HNC lymph node metastasis. An increased level of Lactate dehydrogenase (LDH) has been observed as a major diagnostic metabolomics biomarker for poor survival among HNC patients. It is also recommended as a more efficient biomarker of metastasis. For present study serum samples were collected from healthy controls (n=10) and HNC patients with and without lymph node metastasis (n=10 each). Prepared serum samples were analyzed by UV-spectrophotometer. Further, obtained data were analyzed using the one-way ANOVA test. Significant difference (p<0.05) was reported in the levels of serum metabolites between healthy control group and HNC lymph node metastasis (p<0.0006). Comprehensively, this study provides valuable insights in alteration of serum LDH enzyme level in early diagnosis and prediction of HNC. We proposed LDH could be used as an early metastasis biomarker in screening HNC lymph node metastasis patients.

Key words:Head and neck cancer, Lymph node metastasis, Metabolomics, Lactate dehydrogenase (LDH), Serum .
COMBINING EXTENDED PRODUCER RESPONSIBILITY (EPR) AND DEPOSIT REFUND SYSTEM (DRS) POLICY FOR HIGHER RECOVERY AND RECYCLING OF PLASTIC BOTTLES AND SACHET WATER WASTE: APPLICATION OF VENDING MACHINE AND DESIGNATED RETURN DEPOT CENTRE IN LAGOS, NIGERIA
Authors: Allen-Taylor K. O.
Published: June 2022

Waste management (Plastic, PET Bottle, Can, and Glass Bottle, mostly from drink and beverage packages) is an important issue in today's world, as the volume of waste increases daily. This is especially important in developing countries like Nigeria, where there are no strong institutionalized frameworks for waste management, and as a result, increasing waste poses a threat to human well-being. Given the increase in population in these countries, it is necessary to adopt sustainable and practical solutions. Especially in Lagos, where the environmental problem of plastic waste is on the rise. Although the government is making commendable efforts to reduce the increasing volume of plastic waste in the state, they are insufficient, as it has been reported that plastic waste accounts for 15% of total waste volume according to the Lagos state waste characterization index. However, with the rise in various environmental problems caused by plastic waste, this paper proposed combining the extended producer responsibility (EPR) and deposit refund system (DRS) to achieve a high rate of recovery and recycling of waste plastic bottles and sachets. The innovative approach used green technology (vending machine) as well as indigenous knowledge are practical solutions in Lagos state. The paper is also significant because it intends to implement the developed solution in a dense urban and rural setting in Lagos, which can be replicated in other states in Nigeria. Furthermore, the components discussed in this paper are elements that allow the proposed concept to function effectively and efficiently. The proposed concept will serve as a link between Lagos and Nigeria's current linear economy and the future circular economy of plastic production and management.
REVIEWING THE CONCEPT WASTE HIERARCHY GUIDELINE AND THE ENVIRONMENTAL PROBLEM OF WASTE MANAGEMANET IN LAGOS STATE, NIGERIA
Authors: Allen-Taylor K. O.
Published: June 2022

Environmental and human health problems associated with waste are not limited to littering, pollution, disposal etc. Over the years waste has become a major problem in many developing countries as their population increases. As the volume of waste continues to increase in Lagos State, there is a need to adopt an efficient sustainable policy framework such as the Waste Framework Directive 2008/98/EC (WFD) - also known as the Waste Hierarchy Guideline – that will help resolve part of the plastic waste problems in Lagos State. In this review article, Lagos is used as a case study due to its growing population, urbanization, and industrialization. This literature examines the environmental problems caused by the failure to implement the Waste Hierarchy Guideline as a policy that allows the pursuit of proper waste disposal, management, and environmental protection in Lagos State. As a result, the paper recommends incorporating waste hierarchy options into Lagos state waste management policies to achieve resource conservation, an aftercare-free waste treatment system, and protection for mankind (human health) and the environment.
Urgensi Pendidikan Shalat pada Anak dalam Keluarga; Studi Analisis H?adîth tentang Hukuman bagi Anak Tidak Shalat
Authors: Mustofa Ali , Ishak Ishak
Published: June 2022

The family is the primary educational environment for children. In Islam, education must make people who devote themselves to worship God. And worship was first required is prayer because prayer is pillar of religion. Inside are virtue and wisdom to who do it well as threat to the left. Little kid is not obligated to pray, but the family (parents) have a responsibility and obligation to educate their children, to invite children to pray after a seven year old child, and hit if not want to do the prayer at the age of ten years. But before hitting, parents also need to have educating prayer before age ten. Although the children were not required to prayers, but parents should always pay attention and control the execution of a child prayers. Education prayers in these children very well have implications for the psychological, physical, and social child. Moreover, if the study is successful, the prayer will become a necessity. So the psychiatric, physical, and social child always running stable until in adulthood.
Psikologi Belajar Anak; Telaah Kritis Dinamika Belajar Anak
Authors: Arifin Zainur
Published: June 2022

Learning is a means islamic education people, therefore, learning is a process of behavior change that comes from experience. Learning to not only remember but broader than that, the experience, not a mastery learning outcome results of the exercise but behavior change, learning activities can be lived (experienced) by a person who is learning and can also be observed by others. Psychology of children’s learning is the process of guidance to learners towards the formation of a good muslem personal (perfect man). The success of the students are not separated development of Learning child socio-emotional development of learning children In identity, development of children study in consciousness morality in children, biological development and perceptual learning child physical development children study implications for healthcare and nutrition children all of it as the assessment centers children’s learning.
Peran Supervisi Pendidikan dalam Meningkatkan Profesionalitas Guru
Authors: Ma'sum Muhammad Asrori
Published: June 2022

A conducive and dynamic learning can not deny the role of the teacher as an intermediary of transfer of knowledge to learners. But in reality not a few of the teachers encountered some obstacles that cause less maximal implementation of teaching and learning process. Seeing the facts and phenomena, the teacher is a teacher who is part of human resources components that must be nurtured and developed continuously in the hope to perform its functions professionally. This is where the necessary supervision of education to supervisi and improve teaching and learning process conducted by teachers. The step of the education supervisor should be more focused on how a supervisor and principal can condition the supervisid teacher to cooperate with the supervisor, because the teacher's lack of optimal teaching needs to be discussed between teacher and supervisor and principal so that input from the discussion with teachers is useful for performance improvement teacher in the future.
Standar Bahasa yang Benar antara Bahasa dan Sintak
Authors: Masykur Muhammad Zakki
Published: June 2022

Language is regularly and systematically used by the language user. Basically, language is spoken utterance, verbal arbiter, symbol, symbol, and the signs used in language contain meaning related to life situation and real human experience. If given the understanding of the language, there will be differences of opinion among the linguists. This happens because so wide the scope of the language itself. The development that occurs in the community will also affect the development of the language itself. In its development language requires a method of language itself. And should the standard language itself. How to standard the correct language itself. Whether hasrus corresponds to nahwu, or there is a measure of its own. Departing from this problem we are from a group of 2 modern linguistic courses and its application to Arabic language learning will discuss about the correct language standard between language and nahwu.
Teori Kites dalam Pola Asuh Anak
Authors: Suradi Ahmad
Published: June 2022

Child care pattern must be done with good education, if done wrongly, it will have an impact that is not good for the development of soul and body, and of course also will impact on the surrounding environment. This can be seen from some phenomenon that recently rampant happened. Child care pattern should be done with a good education, if done wrongly, it will have an impact that is not good for the development of the soul and body, and of course also will have an impact on the surrounding environment. Regarding self-preservation, Islam has actually given a warning to humans. The role that humans must perform consists of two paths, namely the horizontal path and the second vertical path. When viewed from various forms of parenting, in essence almost the same. For example autopsy, over protection, over discipline. Domination, favoritism, parental and authoritarian ambition, all emphasize excessive attitudes of power, discipline and obedience.
Tasawuf Education as the Effort of Spiritual and Character Building Capability
Authors: Mustofa Ali
Published: June 2022

Education has role to provide human resources to have high intelctual, spiritual, and having good morals. However, the education has not succeeded as general. There many youths and tenagers misbehave such as interfere general tranquility such as: drunkenness, irregular racing, and adultery. This shows how weak their spiritual and morals. In othersides, non formal education, such as tasawuf is able to create human to be faith and have good morals. The kinds of tasawuf education are syari’ah, thariqah, haqiqah and ma’rifat. meanwhile tasawuf material is practicing wirid, praying and fasting, which aims to integrate body and soul, feeling the meaning of cleanliness heart and the whole character and then achieving the ma’rifat. In tasawuf education, the murshid or teacher teaching, guiding, and training his disciples in order to achieve the intended purpose, namely purification of soul (tazkiyah al-nafs), cleansing of heart (tasfiyah al-qalb) and self-approach to Allah (taqarrub ila allah). The tasawuf education methods which are not found in general education are muhasabah, talqin, mujahadah, and khalwat. Therefore, tasawuf education causes human spiritual characteristic, such as the ability to transcend, sanctify daily experience, and use spiritual potentials to solve problems, ability to be seen in various virtues, and cultivate good morals towards Allah, himself, fellow, environment and nation.
Implementasi Pendekatan Eklektik berbasis Sharing Zone
Authors: Bali Muhammad Mushfi El Iq , Rohmah Lailatur
Published: June 2022

This research aims to determine the effort of guidance in implementing an eclectic approach to foster children. This research was conducted because some students who have difficulty in facing life problems in boarding schools. Through this Sharing Zone activity, students can share story with guidance so they can relieve and solve the problem well. The guidance can provide guidance and direction to their students so that they can be more enthusiastic in undergoing some tiring activities and overcome some problems of their life in Islamic boarding schools. Various personalities of students in boarding schools give some little difficult for guidance to face their students. The Eclectic Approach based on Sharing Zone in Nurul Jadid Islamic Boarding School exactly Al-Hashimiyah Region really produces maximum results. So that the learning spirit existence of students will be maintained in undergoing the intense activities.
Pendekatan Hermeneutika Khaled M. Abou el- Fadl untuk Membedakan antara Ajaran Otoritas dan Otoritarianism
Authors: Unsi Baiq Tuhfatul
Published: June 2022

Islamic law faces trauma of modernity and colonialism which has an impact on the emergence of authoritarian attitudes in treating texts. Authoritarianism is the act of locking will of God, or will of text in a certain determination, and then presenting that determination as a given, definite, absolute, and decisive. According to the analysis of Khaled M. Abou el-Fadl, this phenomenon, especially about the discourse of Islamic law, is the result of mistakes in taking methodological procedures related to the relationship between author, text and reader. The reader that locks the text in a certain meaning, it has damaged the integrity of the author and text itself. In the dimension of authoritarian interpretation, dominant problem in determining is at reader level. Methodology offered by Khaled is a negotiative hermeneutic, where between three text-author-reader elements must be negotiated, pressure point is more on reader without annulling two other elements. Because for him, reader is always experiencing changes and dynamics throughout his life. In addition, readers also have an interest in text. This is due to human being as reader who gives his voice and meaning to text. Three things are needed to maximize this negotiative hermeneutic performance; competence and text validation, determination of meaning and concept of representation.
IMPLEMENTASI PEMBELAJARAN KITAB KUNING MELALUI MODEL PEMBELAJARAN FLIPPED CLASSROOM
Authors: Wijaya Mu’alim , Hasanah Nafilatul
Published: June 2022

In this study explaining the implementation of yellow book learning based on flipped classroom in the Islamic boarding school of Nurul jadid, Zaid bin Tsabit (K) daughter. This research was motivated by the ineffectiveness of santri when studying the Book of Yellow. After being studied more deeply, it turned out that the main factor that caused this was because the learning model carried out by Ustadz was still classic, namely using the lecture model, as a result many santri were sleepy during activities. Therefore, researchers tried using a new learning model, namely the flipped classroom model. This research is a qualitative research carried out in the nurul jadid Islamic boarding school in the zaid bin tsabit (k) region of women, especially the class members of the Takhossus Diny Institute with a sample of 17 people. Flipped classroom is a learning model that is slightly different from the usual, that is before conducting the learning process in the class of students / students learn the subject matter in advance, and teaching and learning activities in the classroom are filled with work and discussing material or problems that students have not understood. Data collection methods in this study include: observation, interviews and documentation.
ANALISIS PERATURAN MENTERI PENDIDIKAN DAN KEBUDAYAAN REPUBLIK INDONESIA NOMOR 22 TAHUN 2016 TENTANG STANDAR PROSES PENDIDIKAN DASAR DAN MENENGAH SERTA IMPLIKASINYA DALAM PEMBELAJARAN PAI DI SEKOLAH
Authors: Hidayat Tatang , Kosasih Aceng
Published: June 2022

Learning process, as one of the core activities in education, is very prominent in realizing national education goals. However, in reality, despite the standard education process has been formulated, the learning process in Indonesia is still poorly developed. The purpose of this discussion is to analyze the regulations of the Minister of Education and Culture of the Republic of Indonesia Number 22 Year 2016 regarding process standards in Primary and Secondary Education and their implications on Islamic Religious Education (PAI) learning in schools. This study uses a qualitative approach and analytical method. Based on the results of the discussion, the primary and secondary education process standards listed in the regulation Number 22 Year 2016 are reliable and comprehensive. The learning principle with a scientific approach has implications on the wholeness of PAI learning process, as the subject is required to be understood comprehensively, not partially. To accomplish this, PAI teachers must use approaches, strategies, methods, techniques, tactics and learning models that are in harmony with the learning material that is delivered, so that an effective and efficient learning process will be achieved.
IMPLEMENTASI PENJAMINAN MUTU MADRASAH
Authors: Prayoga Ari , Widad Azhar Lujjatul , Marliana Elin , Mukarromah Ima Siti , Ruswandi Uus
Published: June 2022

Quality control in the management of education is faced with constraints of limited educational resources. Therefore we need an effort to control quality in the form of guarantees, so that all aspects related to education services provided are in accordance with or exceeding national education standards. This paper aims to describe the implementation of education quality assurance in Madrasah Aliyah An-Najiyah Bandung, including; implementation of madrasah quality assurance, quality implementation obstacles, and solutions in overcoming obstacles to implementing quality assurance in Madrasah aliyah An-Najiyah Bandung. This research uses a qualitative approach through descriptive methods. The data collection techniques using in-depth interviews, observation, and literature study. The results showed that; first, In terms of quality assurance in terms of the eight national education standards in Madrasah Aliyah An-Najiyah, Bandung, it is at a good standard level and even exceeds the minimum service standard so that it becomes a distinct advantage for this madrasa. High competitive power makes the process of implementing quality assurance more stringent. Second, the internal obstacle that arises is the absence of a special quality assurance institution internal to the institution that controls all aspects of quality assurance. Third, the solution to the obstacles that arise will be minimized if institutionally already built.
EFEKTIVITAS PENERAPAN METODE AL-MIFTAH LI AL-ULUM DALAM BELAJAR MEMBACA BUKU KLASIK DI PP. NURUL JADID PAITON PROBOLINGGO
Authors: Rozi Fathor , Zubaidi Ahmad
Published: June 2022

Al-Miftah li al Ulum is a fast method of reading a classical book that was initiated directly by a senior teacher at the Sidogiri Islamic Boarding School in Pasuruan, including one of the learning methods that has an extraordinary appeal towards learning to read the classical book because it uses brief explanations but understands and how to memorize Arabic lafadz positions and formulas which are packaged in Indonesian verses.

Reading the classical book becomes a rare habit. This might be due to the fact that there is no or less interesting method used. Along with the emergence of some interesting methods of reading classical book, the students seemed to find a new paradigm in learning the yellow book.

Based on the background above, what we want to know is about the effectiveness of the application of the al-Miftah li al-Ulum method in learning to read the classical book in Madrasah Diniyah Fatimatuzzahro’ PP. Nurul Jadid Islamic Boarding School Paiton Probolinggo.

Furthermore, according to its type, this research is a qualitative case study type using observation, documentation, and interview methods in the process of collecting data. While the data analysis is an interactive analysis of Miles & Huberman by reducing data, displaying data, verifying data, and finally making conclusions.