bluuebunny/crossref_metadata_2025 huggingface dataset:
Aplikasi Go-Qur’an Berbasis Web dan android
Authors: Yaqin Moh. Ainol
Published: May 2022

Hubungan komunikasi antara pihak masyarakat dengan para Ahlu Al-Qur’an yang mengisi suatu kegiatan sangat penting adanya. Akan tetapi masalah yang sering dihadapi pihak masyarakat dalam setiap menghadirkan para Ahlu Al-Qur’an adalah sedikitnya informasi keberadaan para Ahlu Al-Qur’an serta lemahnya komunikasi antara pihak masyarakat dan Ahlu Al-Qur’an itu sendiri. Untuk mengatasi permasalahan yang telah diuraikan sebelumnya maka diperlukan sebuah solusi dalam bentuk pembuatan aplikasi berbasis website dan android untuk bisa menjadi alat komunikasi antara pihak masyarakat dan Ahlu Al-Qur’an. Model yang digunakan untuk untuk membangun aplikasi ini adalah waterfall. Model waterfall memiliki beberapa tahapan yaitu System Engineering, Requirements, Design, Coding, Testing dan Maintenance. Hasil dari penelitian ini adalah sebuah sistem atau aplikasi yang mampu memberikan kemudahan dalam berkomunikasi antara pihak masyarakat dan Ahlu Al-Qur’an secara cepat dan akurat.
DESAIN JALUR EVAKUASI PENGGUNA BANGUNAN PADA KONDISI DARURAT DI GEDUNG FTI- UMI LANTAI IV MENGGUNAKAN ALGORITMA FLOYD WARSHALL
Authors: Herdianzah Yan , Padhil Ahmad , P A. Dwi Wahyuni , Pawennari Andi , Alisayabana Takdir , Mail Abdul , Alimuddin Taufik , Wibowo Sadiq Ardo
Published: May 2022

It is often assumed that occupational safety and health (K3) is a waste, a waste of cost or just a formality that must be fulfilled by the organization. The K3 procedure in a building is very important especially in a multi-storey building, because in a multi-storey building there are risks that cannot be predicted, for example in the event of an earthquake or fire. Based on the legal aspects of OSH which have been stipulated in Law No. 28 of 2002 concerning building construction, the importance of comfort, safety, health and convenience must be owned by a building. This research is about the evacuation route in the Faculty of Industrial Technology Building, Muslim University of Indonesia, Floor IV Using the Floyd Warshal Algorithm. By using the required data such as building plans, room data used per floor, the number of permanent and temporary building occupants, the results of data processing are obtained from the design drawings of the evacuation route, complete with instructions for safe lane during emergencies.
PENERAPAN KESELAMATAN DAN KESEHATAN KERJA PADA PEKERJA BAGIAN PRODUKSI DI INDUSTRI PENCACAH PLASTIK DENGAN MENGGUNAKAN FAULT TREE ANALYSIS
Authors: Myrtanti Reiny , Suardika Ida Bagus
Published: May 2022

CV Rabbani merupakan industri kecil yang bergerak di bidang pengolahan (pencacahan) plastik, dengan produk akhir yang dihasilkan berupa bijih plastik. Saat ini CV Rabbani belum mempunyai unit yang mengelola sistem manajemen keselamatan dan kesehatan kerja (K3) dan pekerja-pekerjanya juga belum dilibatkan dalam upaya menerapkan K3, dikarenakan usaha ini masih merupakan usaha kecil dan memiliki SDM dengan jumlah sedikit (tidak lebih dari 10 orang), serta masih belum adanya kesadaran dalam menerapkan K3 di lingkungan kerjanya. Oleh karena itu, diperlukan adanya evaluasi dan analisis, terutama yang terkait dengan kesehatan dan keselamatan kerja. Tujuan dari penelitian ini adalah untuk mengetahui proses pengelolaan manajemen K3, bahaya kecelakaan kerja dan faktor penyebab kecelakaan kerja yang terjadi di CV Rabbani. Metode yang digunakan dalam penelitian ini adalah Fault Tree Analysis (FTA), merupakan metode yang mudah diterapkan dan digunakan untuk mengidentifikasi potensi bahaya, mengevaluasi faktor penyebab kecelakaan kerja dalam setiap aktifitas perusahaan untuk mengurangi resiko kecelakaan kerja, serta menganalisis proses pengelolaan Sistem Manajemen Keselamatan dan Kesehatan Kerja (SMK3) dengan melibatkan pekerja-pekerja di perusahaan dan diharapkan zero accident dapat tercapai.
STRATEGI KEBERLANJUTAN PASCA PANDEMI COVID-19 PADA INDUSTRI KREATIF BERBASIS PONTENSI DAERAH (Studi Kasus UMKM UD Arshaindo Gresik)
Authors: Narto Narto , Junianto Dwi , HM Gatot
Published: May 2022

Usaha Mikro, Kecil, dan Menengah (UMKM) merupakan industri kreatif yang mampu berkontribusi dalam meningkatkan perekonomian nasional di masa pandemi Covid-19. Industri kreatif yang mengelola hasil potensi daerah diharapkan dapat berperan penting dalam mengurangi dampak global pasca pandemi Covid-19. UD Arshaindo, salah satu UMKM dalam pengelolaan hasil tambak ikan merupakan potensi unggulan di Kabupaten Gresik. Beberapa faktor yang dihadapi selama pandemi, mengakibatkan penurunan tingkat penjualan. Berbagai kebijakan keringanan yang diberikan pemerintah di awal tahun 2022, memberikan peluang bagi para pelaku UMKM untuk bangkit melakukan berbagai peningkatan kinerja. Untuk mengatasi hal tersebut, diperlukan strategi keberlanjutan agar mampu bersaing pasca pandemi Covid-19. Untuk itu diperlukan analisis internal dan eksternal dengan menggunakan metode SWOT melalui pemetaan kekuatan, kelemahan, peluang, ancaman. Tujuan dari penelitian ini adalah untuk mengetahui kondisi UMKM UD Arshaindo pada masa pandemi Covid-19 dan menyusun strategi keberlanjutan pasca pandemi Covid-19 pada industri kreatif berbasis potensi daerah. Hasil penelitian menunjukkan bahwa UD Arshaindo berada pada kuadran V. Alternatif strategi keberlanjutan yang dilakukan adalah penambahan pasokan bahan baku dan mesin produksi untuk menghasilkan produk yang berkualitas, membangun mitra kerjasama dengan pemerintah daerah dalam bidang pemberdayaan pengolahan tambak yang menghasilkan ikan sebagai andalan. bahan baku produk dan retail antar daerah untuk meningkatkan segmentasi pasar dengan memaksimalkan platform teknologi digital.
Chemoenzymatic Synthesis of Asymmetrically Branched Human Milk Oligosaccharide Lacto-N-Hexaose
Authors: Ooi Kai-Eng , Zhang Xiu-Wen , Kuo Cheng-Yu , Liu Ying-Jia , Yu Ching-Ching
Published: May 2022

We herein reported the first chemoenzymatic synthesis of lacto-N-hexaose (LNH) by combining chemical carbohydrate synthesis with a selectively enzymatic glycosylation strategy. A tetrasaccharide core structure GlcNH2β1→3 (GlcNAcβ1→6) Galβ1→4Glc, a key precursor for subsequent enzymatic glycan extension toward asymmetrically branched human milk oligosaccharides, was synthesized in this work. When the order of galactosyltransferase-catalyzed reactions was appropriately arranged, the β1,4-galactosyl and β1,3-galactosyl moieties could be sequentially assembled on the C6-arm and C3-arm of the tetrasaccharide, respectively, to achieve an efficient LNH synthesis. Lacto-N-neotetraose (LNnH), another common human milk oligosaccharide, was also synthesized en route to the target LNH.
Study Protocol for the Peruvian Registry of Advanced Heart Failure (REPICAV)
Authors: Chacón-Diaz Manuel , Laymito Quispe Rocío , Hernández-Vásquez Akram , Vargas-Fernández Rodrigo
Published: May 2022

Background

Heart failure (HF) is a global problem with a high mortality rate, and advanced HF (AHF) represents the stage with the highest morbidity and mortality. We have no local data on this population and its treatment. The aim of this study will be to determine the epidemiological, clinical, therapeutic, and annual survival characteristics of patients diagnosed with AHF treated in hospitals with HF units in the city of Lima, Peru.

Methods and Analysis

An observational, prospective, multicenter study will be conducted with evaluation at baseline and follow-up at 1, 3, 6, and 12 months after study entry. Patients over 18 years of age with AHF seen in referral health facilities in metropolitan Lima will be included. The cumulative mortality during follow-up will be estimated by the Kaplan-Meier method, and Cox regression models will calculate hazard ratios (HRs) and 95% confidence intervals (CI). Likewise, risk ratio (RR) and 95% CI will be estimated using generalized linear models with binomial family and log link function. This study was approved by the Ethics and Research Committee of the National Cardiovascular Institute (Instituto Nacional Cardiovascular “Carlos Alberto Peschiera Carrillo”—INCOR [in Spanish]; Approval report 46/2021-CEI).

Discussion

In Peru, there are no scientific data on the epidemiology of AHF in the population. This means that physicians are not adequately trained in the characteristics of the Peruvian population to identify patients who could be candidates for advanced therapies and to recognize the optimal time to refer these patients to more complex HF units. This study will be the first to examine the clinical-epidemiological characteristics of AHF in Peru with a follow-up of 1 year after the event and will provide relevant information on these observable characteristics for the management of high-complexity patients.
Seasonal Variation in Resource Overlap Between Red Swamp Crayfish (Procambarus clarkii) and Native Species in Poyang Lake Wetland, China
Authors: Wu Jiajia , Chen Huili , Jin Binsong , Winemiller Kirk O. , Wu Shenhao , Xu Wang , Zhang Huan , Wu Xiaoping
Published: May 2022

Biological invasions are a significant component of current global environmental change that affect biodiversity as well as ecosystem processes and services. The red swamp crayfish (Procambarus clarkii) is one of the most invasive species worldwide, with a documented ability to deplete basal food resources and alter the structure of aquatic food webs. The red swamp crayfish has extensively invaded the Poyang Lake wetland, located in the middle reach of the Yangtze River basin. Here, we use an isotopic mixing model (MixSIAR) with data from stable isotope ratios (δ13C, δ15N) to estimate relative contributions of potential resources to the biomass of red swamp crayfish and ten common native species, and we use hierarchical clustering analysis to assess basal resource breadth and interspecific similarity of invasive and native species. We hypothesized that red swamp crayfish and several native species have similar trophic niches and may compete for basal resources. Results from the mixing model demonstrated seasonal variation in the basal resource of all species, including the red swamp crayfish and native snails, prawns, and fishes. Submerged macrophytes and detritus were estimated to be the most important sources during the rising-water season; during the high-water season, emergent macrophytes and detritus were most important; and during the falling-water season, detritus, POM, and floating macrophytes were most important. Resource overlap was substantial between the invasive crayfish and dominant native species, particularly the freshwater snail (Bellamya aeruginosa), indicating the potential exists for negative impact from competition under conditions of resource limitation.
Lactobacillus casei Ghosts as a Vehicle for the Delivery of DNA Vaccines Mediate Immune Responses
Authors: Yu Xiaoli , Wang Li , Yang Xinru , Zhang Songsong , Li Guiwei , Zhang Lanlan , Li Jiaxuan , Wang Xiaona , Zhou Han , Jiang Yanping , Cui Wen , Li Yijing , Tang Lijie , Qiao Xinyuan
Published: May 2022

We developed Lactobacillus casei bacterial ghosts (BGs) as vehicles for delivering DNA vaccines and analyzed their effects on immune responses. Uptake of the plasmids encoding the enhanced green fluorescent protein (pCI-EGFP) and BGs loaded with pCI-EGFP by macrophages was investigated using fluorescence microscopy and flow cytometry. The results showed that pCI-EGFP-loaded L. casei BGs were efficiently taken up by macrophages. Lactobacillus casei BGs loaded with plasmids encoding VP6 protein of PoRV (pCI-PoRV-VP6) significantly upregulated the mRNA expression of interleukin (IL)-1β, IL-10, tumor necrosis factor (TNF)-α, inducible nitric oxide synthase (iNOS), arginase-1 (Arg-1), Mannose receptor (CD206) toll-like receptor (TLR)-2, TLR4, and TLR9 in macrophages. The levels of markers of M1 polarization (IL-10 and TNF-α) and M2 polarization (Arg-1 and CD206) were increased in macrophages incubated with pCI-PoRV-VP6-loaded BGs compared with the control group. The results of the enzyme-linked immunosorbent assay showed that the secretion of IL-1β, IL-10, and TNF-α in macrophages was significantly upregulated compared with the control group. Flow cytometry demonstrated that L. casei BGs loaded with pCI-PoRV-VP6 promoted the maturation of dendritic cells (DCs). Following incubation with pCI-PoRV-VP6-loaded BGs, the mRNA expression levels of IL-1β, IL-6 and interferon (IFN)-γ in DCs were significantly increased. ELISA assay showed the secretion of the IL-1β, IL-6, IFN-γ IL-10 and TNF-α in DCs were upregulated significantly. Thus, L. casei BGs promoted the maturation and activation of DCs. We analyzed the stimulatory capacity of DCs in a mixed lymphocyte reaction with allogeneic T cells. T cell proliferation increased upon incubation with DCs stimulated by BGs. After immunizing mice with BGs loaded with pCI-PoRV-VP6, the specific IgG levels in the serum were higher than those elicited by BGs loaded with pCI-PoRV-VP6. BGs loaded with pCI-PoRV-VP6 on Th1 and Th2 cytokines polarized T cells into the Th1 type and increased the proportion of CD4+/CD8+ T cells. These results indicate L. casei BGs effectively mediate immune responses and can be used as delivery system for DNA vaccination.
Serum Soluble Mediator Profiles and Networks During Acute Infection With Distinct DENV Serotypes
Authors: Coutinho-da-Silva Mikelly Santos , Sucupira Pedro Henrique Ferreira , Bicalho Kelly Alves , Campi-Azevedo Ana Carolina , Brito-de-Sousa Joaquim Pedro , Peruhype-Magalhães Vanessa , Rios Maria , Teixeira-Carvalho Andréa , Coelho-dos-Reis Jordana Grazziela Alves , Antonelli Lis Ribeiro do Valle , Rezende Vitor Bortolo de , Melo Fernanda Ludolf Ribeiro de , Garcia Cristiana Couto , Silva-Andrade Jesuanne Carla , Costa-Rocha Ismael Artur da , Bastos Michele de Souza , Rocha Lucia Alves da , Silva Valderjane Aprigio , Ferreira Ewerton da Silva , Marinho Eveny Perlize Melo , Costa Allyson Guimarães , Gomes Matheus de Souza , Amaral Laurence Rodrigues , Furtado Erilene Cristina da Silva , Silva Eliana Vieira Pinto da , Ramos Bruna Alves , Santos Éder Barros dos , Freitas Maria Nazaré Oliveira , Vasconcelos Pedro Fernando da Costa , Martins-Filho Olindo Assis , Araújo Márcio Sobreira Silva , Ferreira Milene Silveira , Martins Livia Carício
Published: May 2022

A panoramic analysis of chemokines, pro-inflammatory/regulatory cytokines, and growth factors was performed in serum samples from patients with acute DENV infection (n=317) by a high-throughput microbeads array. Most soluble mediators analyzed were increased in DENV patients regardless of the DENV serotype. The substantial increase (≥10-fold) of CXCL10, IL-6, and IFN-γ, and decreased levels of PDGF (<0.4-fold) was universally identified in all DENV serotypes. Of note, increased levels of CXCL8, CCL4, and IL-12 (≥3-9-fold) were selectively observed in DENV2 as compared to DENV1 and DENV4. Heatmap and biomarker signatures further illustrated the massive release of soluble mediators observed in DENV patients, confirming the marked increase of several soluble mediators in DENV2. Integrative correlation matrices and networks showed that DENV infection exhibited higher connectivity among soluble mediators. Of note, DENV2 displayed a more complex network, with higher connectivity involving a higher number of soluble mediators. The timeline kinetics (Day 0-1, D2, D3, D4-6) analysis additionally demonstrated differences among DENV serotypes. While DENV1 triggers a progressive increase of soluble mediators towards D3 and with a decline at D4-6, DENV2 and DENV4 develop with a progressive increase towards D4-6 with an early plateau observed in DENV4. Overall, our results provided a comprehensive overview of the immune response elicited by DENV infection, revealing that infection with distinct DENV serotypes causes distinct profiles, rhythms, and dynamic network connectivity of soluble mediators. Altogether, these findings may provide novel insights to understand the pathogenesis of acute infection with distinct DENV serotypes.
LuxS in Lactobacillus plantarum SS-128 Improves the Texture of Refrigerated Litopenaeus vannamei: Mechanism Exploration Using a Proteomics Approach
Authors: Li Yuan , Qian Yilin , Lou Xiaowei , Hu Zhiheng , Hu Yaqin , Zeng Mingyong , Liu Zunying
Published: May 2022

This study illustrated the texture changes of Shewanella baltica-inoculated Litopenaeus vannamei during refrigerated storage with the exogenous addition of Lactobacillus plantarum SS-128. The group inoculated with SS-128 had an improved texture compared with that inoculated with the luxS-mutant group (ΔluxS). Proteomics were conducted to analyze the protein alterations in L. vannamei and supernatant, respectively. During storage, many texture-related proteins, including myosin heavy chain and beta-actin, were maintained due to luxS. Some endogenous enzymes related to the energy metabolism and hydrolysis of L. vannamei were downregulated. The luxS-induced interaction with S. baltica showed significant changes in the expression of some critical enzymes and pathways. The ATP-dependent zinc metalloprotease FtsH and protease subunit HslV were downregulated, and the oxidative phosphorylation and glycosaminoglycan degradation pathways in S. baltica were inhibited, resulting in the slow deterioration of L. vannamei. By exploring the mechanism underlying SS-128-led manipulation of the metabolism of spoilage bacteria, we clarified the texture maintenance mechanism of luxS in SS-128, providing theoretical evidence for SS-128 application in food preservation.
Reducing Early Antibiotic Use: A Quality Improvement Initiative in a Level III Neonatal Intensive Care Unit
Authors: Morales-Betancourt Catalina , De la Cruz-Bértolo Javier , Muñoz-Amat Bárbara , Bergón-Sendín Elena , Pallás-Alonso Carmen
Published: May 2022

Antibiotic burden is a critical issue in neonatal intensive care units (NICU) and antibiotic use is considered a quality indicator of neonatal care. Our aim was to optimize antibiotic use through a quality improvement (QI) initiative that included revision of departmental protocols and implementation of a surveillance system based on process indicators.

Methods

This is descriptive study of a cohort of all very low birth weight (VLBW) infants admitted to the NICU from 2014 to 2019. A series of QI interventions were made during the study period and included departmental protocols and the implementation of a surveillance system based on process indicators. The primary outcome was the percentage of VLBW infants who had received early antibiotics (ampicillin, gentamicin, or cefotaxime on the day of birth or day 1 or 2 after birth), antibiotics for longer than 3 days (despite negative blood culture), or no antibiotics.

Results

During the study period, a significant relative reduction was seen in the proportion of VLBW infants administered early antibiotics (46%; p < 0.01) and in infants provided antibiotics for longer than 3 days (90%; p < 0.01). Additionally, the percentage of VLBW with “no antibiotics” during their NICU stay increased fivefold (6 to 30%; p < 0.001).

Conclusions

In our NICU, the implementation of a QI initiative that is based on affordable methods to track process indicators and evaluate the results led into a significant reduction in antibiotic exposure in VLBW infants. This approach is easy to implement in other NICUs as well.
The Role of Worldviews in Predicting Support for Recreational Cannabis
Authors: Sammut Gordon , Mifsud Rebekah , Brockdorff Noellie
Published: May 2022

We studied the role of worldviews in the endorsement of proposals for the legalisation of recreational cannabis. Drawing on literature on generalised belief structures, we developed categorical measures for five worldviews drawing on commonalities in the typologies reviewed (Orthodox, Localised, Reward, Pragmatist, and Survivor). We proceeded to study the relative influence of worldviews in support of a range of items concerned with the legalisation of recreational cannabis amongst a randomly generated sample (N = 1000) in Malta. Our findings demonstrate that the Orthodox worldview stands in contrast to all others in opposing the proposals and constitutes the resistance group to legalisation. On the other hand, no other worldview unilaterally supports the proposals albeit these are, on an individual basis, favourably perceived. Our study further demonstrates that proportions of variance accounted for by the worldview measures we adopted are comparable to those exercised by demographic variables demonstrating significance. We propose that the study of worldviews is critical in understanding social and political alliances that come together to support or oppose particular politicised projects or collective courses of action.
On the Choice of the Item Response Model for Scaling PISA Data: Model Selection Based on Information Criteria and Quantifying Model Uncertainty
Authors: Robitzsch Alexander
Published: May 2022

In educational large-scale assessment studies such as PISA, item response theory (IRT) models are used to summarize students’ performance on cognitive test items across countries. In this article, the impact of the choice of the IRT model on the distribution parameters of countries (i.e., mean, standard deviation, percentiles) is investigated. Eleven different IRT models are compared using information criteria. Moreover, model uncertainty is quantified by estimating model error, which can be compared with the sampling error associated with the sampling of students. The PISA 2009 dataset for the cognitive domains mathematics, reading, and science is used as an example of the choice of the IRT model. It turned out that the three-parameter logistic IRT model with residual heterogeneity and a three-parameter IRT model with a quadratic effect of the ability θ provided the best model fit. Furthermore, model uncertainty was relatively small compared to sampling error regarding country means in most cases but was substantial for country standard deviations and percentiles. Consequently, it can be argued that model error should be included in the statistical inference of educational large-scale assessment studies.
High Refractive Index Diphenyl Sulfide Photopolymers for Solar Cell Antireflection Coatings
Authors: Zhang Jingran , Li Baozhu , Song Heran , Zhao Chen , Liang Songfeng , Dong Zhurong , Yu Jie
Published: May 2022

The anti-reflection film can effectively reduce the surface reflectivity of solar photovoltaics, increase the transmittance of light, and improve the photoelectric conversion efficiency. The high refractive index coating is an important part of the anti-reflection film. However, the traditional metal oxide coating has poor stability and complicated processes. To address this issue, we prepared two organic high refractive index (HRI) photopolymers by modifying epoxy acrylic acid with 4,4′-thiodibenzenethiol, which can be surface patterned by nanoimprinting to prepare antireflection coatings. As a result, two modified photopolymers with high refractive index (n > 1.63), high optical transmittance (T > 95%), and thermal stability (Tg > 100 °C) are obtained after curing. In particular, the diphenyl sulfide photopolymer modified by ethyl isocyanate acrylate has a refractive index up to 1.667 cured by UV light. Our work confirms that the organic HRI photopolymer can be obtained by introducing high molar refractive index groups, with potential to be applied as a PV cell power conversion efficiency material.
Optimization Study on Microwave-Assisted Hydrothermal Liquefaction of Malaysian Macroalgae Chaetomorpha sp. for Phenolic-Rich Bio-Oil Production
Authors: Ong Mei Yin , Nomanbhay Saifuddin
Published: May 2022

There are several methods of biomass conversion, including hydrothermal liquefaction (HTL). The implementation of microwave technology in the HTL process is still new, especially on the conversion of marine biomass into bio-crude. In this work, the macroalgae Chaetomorpha sp. was used as the biomass feedstock to produce phenolic-rich bio-oil through microwave-assisted HTL. Chaetomorpha sp. was abundantly found in Malaysia, creating a green tides issue. By utilizing these algae, the green tide issue can be solved and value-added bio-oil is obtained. However, bio-oil from macroalgae has a relatively low heating value, restricting its fuel application. Therefore, it is suggested to be used for bio-polymer synthesis, including bio-based phenol formaldehyde. In this study, the effect of different parameters, such as reaction temperature, preloaded pressure, water-to-algal biomass ratio, and holding time, on both the bio-oil yield and phenolic yield was evaluated. Folin–Ciocalteu method was introduced as the phenolic determination method and the optimal conditions were located by using Response Surface Methodology (RSM). As a results, an optimal biodiesel yield and phenolic yield of 21.47 wt% and 19.22 wt% Gallic Acid Equivalent was obtained at a reaction temperature of 226 °C, 42 bar preloaded pressure and 30:1 water-to-algal biomass ratio after 79 min. Sensitivity analysis also concluded that the water-to-algal biomass ratio is the most influential factor, followed by the preloaded pressure. The FTIR spectrum of the bio-oil produced indicated the presence of different functional group of compounds. In short, Chaetomorpha sp. has been successfully converted into valuable bio-oil through microwave-assisted HTL.
Modelling of Battery Energy Storage System Providing FCR in Baltic Power System after Synchronization with the Continental Synchronous Area
Authors: Groza Edgars , Kiene Santa , Linkevics Olegs , Gicevskis Karlis
Published: May 2022

This paper presents the case study of provisions of frequency containment reserve (FCR) with a battery electric storage system (BESS). The aim of the case study is the evaluation of the technical possibility to provide FCR in Latvian power systems after all Baltic power systems will synchronize with the Continental Europe Synchronous Area (CESA). To simulate the dynamics of BESS capacity and its state of charge (SOC), authors have developed an algorithm and mathematical model (it can be realized in different calculation programs). The case study calculations verified the model. The algorithm is conditionally divided into two parts—FCR provision and SOC recovery–which in turn is divided into three possible models of BESS state of charge recovery options: (1) overfulfillment—exceeding the specified FCR amount, (2) deadband utilization, and (3) BESS charging or discharging through scheduled transactions in intraday power market. The modelling was performed using historic frequency data of Latvian and French power systems. The case study of BESS with charging capacity of 12 MW and stored energy volume of 7 MWh for provision of determined FCR for Latvian power system was considered. The obtained results from the simulation were used in the separate model to evaluate economic feasibility of BESS for FCR.
Social Support and Acculturative Stress of International Students
Authors: Kristiana Ika Febrian , Karyanta Nugraha Arif , Simanjuntak Ermida , Prihatsanti Unika , Ingarianti Tri Muji , Shohib Muhammad
Published: May 2022

Continuing to study abroad brings challenges, apart from academic demands. International students are prone to acculturation stress as a consequence of cultural differences. Many research reports show that social support is a great buffer against experienced stress, but there has thus far been no study that analyzes the real effect of social support on acculturation stress. This meta-analysis study aims to investigate the true effect of social support on acculturation stress of international students based on studies reporting it. A meta-analysis was performed following PRISMA. The electronic databases used were Science-Direct, ERIC, ProQuest, Google Scholar (only for ETD), and opengrey.edu, with the article year limitations being 2009–2019. Eight (8) studies were involved in the meta-analysis. There were three instruments of acculturation stress and five instruments of social support that were used in the different studies. The effect size analysis showed that there was no difference in the effects of eight studies (z = −0.553; SE = 0.497; 95% CI = −1.248–−0.699; p = 0.580). Furthermore, there was no statistically significant moderator variable, the instruments used were quite diverse. The role of a moderator, other than gender, was not used because of limited information from the studies used. Social support plays a major role in reducing acculturation stress in international students. However, studies involving moderator and confounding roles need to be conducted.
Natural Marine Products: Anti-Colorectal Cancer In Vitro and In Vivo
Authors: Han Ningning , Li Jianjiang , Li Xia
Published: May 2022

Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more efficient drugs for clinical trials is vital and urgent. Natural marine compounds, with rich resources and original chemical structures, are applied widely in anticancer treatments. We provide a systematic overview of recently reported marine compounds such as alkaloids, peptides, terpenoids, polysaccharides, and carotenoids from in vitro, in vivo, and clinical studies. The in vitro studies summarized the marine origins and pharmacological mechanisms, including anti-proliferation, anti-angiogenesis, anti-migration, anti-invasion, the acceleration of cycle arrest, and the promotion of tumor apoptosis, of various compounds. The in vivo studies outlined the antitumor effects of marine compounds on colorectal cancer model mice and evaluated their efficacy in terms of tumor inhibition, hepatotoxicity, and nephrotoxicity. The clinical studies summarized the major chemical classifications and targets of action of the clinical drugs that have entered clinical approval and completed approval for marine anticancer. In summary, we present the current situation regarding the application of natural anti-colorectal cancer marine compounds and prospects for their clinical application.
Nutrient Deprivation Coupled with High Light Exposure for Bioactive Chrysolaminarin Production in the Marine Microalga Isochrysis zhangjiangensis
Authors: Ran Xiuyuan , Shen Yuhan , Jiang Dongjian , Wang Chenqi , Li Xinghui , Zhang Haoyu , Pan Yunyun , Xie Chenglin , Xie Tonghui , Zhang Yongkui , Yao Changhong
Published: May 2022

Chrysolaminarin, a kind of water-soluble bioactive β-glucan produced by certain microalgae, is a potential candidate for food/pharmaceutical applications. This study identified a marine microalga Isochrysis zhangjiangensis, in which chrysolaminarin production was investigated via nutrient (nitrogen, phosphorus, or sulfur) deprivations (-N, -P, or -S conditions) along with an increase in light intensity. A characterization of the antioxidant activities of the chrysolaminarin produced under each condition was also conducted. The results showed that nutrient deprivation caused a significant increase in chrysolaminarin accumulation, though this was accompanied by diminished biomass production and photosynthetic activity. -S was the best strategy to induce chrysolaminarin accumulation. An increase in light intensity from 80 (LL) to 150 (HL) µE·m−2·s−1 further enhanced chrysolaminarin production. Compared with -N, -S caused more suitable stress and reduced carbon allocation toward neutral lipid production, which enabled a higher chrysolaminarin accumulation capacity. The highest chrysolaminarin content and concentration reached 41.7% of dry weight (%DW) and 632.2 mg/L, respectively, under HL-S, with a corresponding productivity of 155.1 mg/L/day achieved, which exceeds most of the photoautotrophic microalgae previously reported. The chrysolaminarin produced under HL-N (Iz-N) had a relatively competitive hydroxyl radical scavenging activity at low concentrations, while the chrysolaminarin produced under HL-S (Iz-S) exhibited an overall better activity, comparable to the commercial yeast β-glucan, demonstrating I. zhangjiangensis as a promising bioactive chrysolaminarin producer from CO2.
Seaweed-Derived Polysaccharides Attenuate Heat Stress-Induced Splenic Oxidative Stress and Inflammatory Response via Regulating Nrf2 and NF-κB Signaling Pathways
Authors: Liu Wen-Chao , Zhuang Di-Pai , Zhao Yue , Balasubramanian Balamuralikrishnan , Zhao Zhi-Hui
Published: May 2022

With global warming, heat stress (HS) has become a worldwide concern in both humans and animals. The ameliorative effect of seaweed (Enteromorpha prolifera) derived polysaccharides (SDP) on HS-induced oxidative stress and the inflammatory response of an immune organ (spleen) was evaluated using an animal model (Gallus gallus domesticus). In total, 144 animals were used in this 4-week trial and randomly assigned to the following three groups: thermoneutral zone, HS, and HS group supplemented with 1000 mg/kg SDP. Dietary SDP improved the antioxidant capacity and reduced the malondialdehyde (MDA) of the spleen when exposed to HS, regulated via enhancing nuclear factor erythroid 2-related factor-2 (Nrf2) signaling. Furthermore, the inclusion of SDP reduced the levels of pro-inflammatory cytokines and alleviated HS-induced splenic inflammatory response by suppressing the nuclear factor-kappa B (NF-κB) p65 signaling. These findings suggest that the SDP from E. prolifera can be used as a functional food and/or feed supplement to attenuate HS-induced oxidative stress and inflammatory responses of the immune organs. Moreover, the results could contribute to the development of high-value marine products from seaweed for potential use in humans and animals, owing to their antioxidant and anti-inflammatory effects.
Sticking Together an Updated Model for Temporary Adhesion
Authors: Bertemes Philip , Grosbusch Alexandra L. , Geschwindt Anik , Kauffmann Bob , Salvenmoser Willi , Mertens Birte , Pjeta Robert , Egger Bernhard , Ladurner Peter
Published: May 2022

Non-parasitic flatworms are known to temporarily attach to the substrate by secreting a multicomponent bioadhesive to counteract water movements. However, to date, only species of two higher-level flatworm taxa (Macrostomorpha and Proseriata) have been investigated for their adhesive proteins. Remarkably, the surface-binding protein is not conserved between flatworm taxa. In this study, we sequenced and assembled a draft genome, as well as a transcriptome, and generated a tail-specific positional RNA sequencing dataset of the polyclad Theama mediterranea. This led to the identification of 15 candidate genes potentially involved in temporary adhesion. Using in situ hybridisation and RNA interference, we determined their expression and function. Of these 15 genes, 4 are homologues of adhesion-related genes found in other flatworms. With this work, we provide two novel key components on the flatworm temporary adhesion system. First, we identified a Kringle-domain-containing protein (Tmed-krg1), which was expressed exclusively in the anchor cell. This in silico predicted membrane-bound Tmed-krg1 could potentially bind to the cohesive protein, and a knockdown led to a non-adhesive phenotype. Secondly, a secreted tyrosinase (Tmed-tyr1) was identified, which might crosslink the adhesive proteins. Overall, our findings will contribute to the future development of reversible synthetic glues with desirable properties for medical and industrial applications.
Talaromarins A–F: Six New Isocoumarins from Mangrove-Derived Fungus Talaromyces flavus TGGP35
Authors: Cai Jin , Zhu Xiao-Chen , Zeng Wei-Nv , Wang Bin , Luo You-Ping , Liu Jing , Chen Min-Jing , Li Gao-Yu , Huang Guo-Lei , Chen Guang-Ying , Xu Jing , Zheng Cai-Juan
Published: May 2022

Six new isocoumarin derivative talaromarins A-F (1–6), along with 17 known analogues (7–23), were isolated from the mangrove-derived fungus Talaromyces flavus (Eurotiales: Trichocomaceae) TGGP35. Their structures were identified by detailed IR, UV, 1D/2D NMR and HR-ESI-MS spectra. The absolute configurations of new compounds were determined by the modified Mosher’s method and a comparison of their CD spectra with dihydroisocoumarins described in the literature. The antioxidant, antibacterial, anti-phytopathogenic and inhibitory activity against α-glucosidase of all the isolated compounds were tested. Compounds 6–11, 17–19 and 21–22 showed similar or better antioxidant activity than the IC50 values ranging from 0.009 to 0.27 mM, compared with the positive control trolox (IC50 = 0.29 mM). Compounds 10, 18, 21 and 23 exhibited strong inhibitory activities against α-glucosidase with IC50 values ranging from 0.10 to 0.62 mM, while the positive control acarbose had an IC50 value of 0.5 mM. All compounds showed no antibacterial or anti-phytopathogenic activity at the concentrations of 50 μg/mL and 1 mg/mL, respectively. These results indicated that isocoumarins will be useful to developing antioxidants and as diabetes control agents.
Influences of Mg17Al12 Phase Morphology on the Mechanical Properties of AZ80 Magnesium Alloy Subjected to Aging
Authors: Xu Zuo , Huang Lixin , Li Meng , Zhu Zhihua , Liu Chunhai
Published: May 2022

The influence of Mg17Al12 phase morphology on the mechanical properties of AZ80 magnesium alloy subjected to aging was studied. Scanning electron microscopy, X-ray diffraction analysis and hardness indentation were used to reveal the microstructural evolution and mechanical properties of alloys during aging. The results show that Mg17Al12 phase mostly formed at grain boundaries with discontinuous lamellas morphology during aging at 150 °C. In contrast, continuous short rod and spherical Mg17Al12 particles formed transgranularly as aged at 320 °C. Both the strength of the alloy and elongation under room temperature were slightly improved via 150 °C aging.
Photochemistry of Metal Nitroprussides: State-of-the-Art and Perspectives
Authors: Crespo Paula M. , Odio Oscar F. , Reguera Edilso
Published: May 2022

This contribution summarizes the current state in the photochemistry of metal nitroprussides, which is dominated by the electronic structure of the nitrosyl group. From the combination of p orbitals of the nitrogen and oxygen atoms in the NO+ ligand, a π*NO molecular orbital of relatively low energy is formed, which has π*2px and π*2py character. This is a double degenerate orbital. When the nitrosyl group is found coordinated to the iron atom in the nitroprusside ion, the availability of that low energy π*NO orbital results in light-induced electronic transitions from the iron atom dxy, dxz and dyz orbitals, 2b2 (xy) → 7e (π*NO) and 6e (xz,yz) → 7e (π*NO), which are observed at 498 and 394 nm, respectively. These light-induced transitions and the possibility of NO isomer formation dominate the photochemistry of metal nitroprussides. In this feature paper, we discuss the implications of such transitions in the stability of coordination compounds based on the nitroprusside ion in the presence of water molecules for both 3D and 2D structures, including the involved degradation mechanisms. These photo-induced electronic transitions modify the physical and functional properties of solids where the nitroprusside ion forms part of their structure and appear as an opportunity for tuning their magnetic, electrical, optical and as energy-applied materials, for instance. This contribution illustrates these opportunities with results from some recently reported studies, and possible research subjects, even some not explored, are mentioned.
The influence of adding herbal ingredients to the soft cheese «Adygeisky»
Authors:   South Ural State University, Chelyabinsk, Toshev A.J. , Zobnina A.V. ,   South Ural State University, Chelyabinsk
Published: May 2022

In the article, the authors are trying to prove the positive effect of adding herbal ingredients, namely white sesame flour, to the technology for developing Adygeisky soft cheese. This article presents the beneficial properties of white sesame flour when added to the production of soft cheeses. It has been established that this plant component has a beneficial effect on the body, being a good prevention means. This allows concluding that the addition of vegetable raw materials has prospects for further study and implementation in the production of soft cheeses.
Prospects for using a regional vegetable ingredient in the production of flour confectionery
Authors:   South Ural State University, Shcherbakova E.I. , Sadrieva V.V. ,   South Ural State University
Published: May 2022

The necessity of developing functional additives for flour confectionery products is considered. Rose hips is a regional herbal ingredient that can be used as a functional supplement. The useful properties of rose hips are listed. The positive effects of plant components on the human body are described.
On compliance with regulatory requirements for tea labeling
Authors:   Donetsk National University of Economics and Trade named after Mykhailo Tugan-Baranovsky, Donetsk, Donetsk People's Republic, Kudinova O.V. , Popova O.S. ,   Donetsk National University of Economics and Trade named after Mykhailo Tugan-Baranovsky, Donetsk, Donetsk People's Republic
Published: May 2022

The paper analyzes the labeling of green tea samples for compliance with the requirements of regulatory documentation. Violations of tea labeling for a number of legal documents regarding the completeness and correctness of labeling data have been found.
Art therapy as a technique of social work with the elderly and disabled living in a residential care facility
Authors:   FSBEI HE Magnitogorsk State Technical University named after G. I. Nosov, Ispulova Svetlana Nikolaevna , Pogorelskaya Aleksandra Alekseevna ,   FSBEI HE Magnitogorsk State Technical University named after G. I. Nosov
Published: May 2022

Traditionally, art therapy techniques are considered as tools for the psychologist’s work. However, in recent decades, art therapy has been used not only by psychologists, but also by social therapists, specialists in social work. In this article, the authors reveal the features of art therapy as a technique of social work with the elderly and the disabled in a residential care facility.
Do teachers need a Teacher Rights Commissioner in the Russian Federation?
Authors:   ANO VO ", Rozhko G.B. ,   Moscow Humanitarian University",   , Moscow
Published: May 2022

The author of the article reflects on whether the post of Commissioner for Teachers' Rights is needed in the country.
Russian experience of heat-and energy supply hybrid systems implementation
Authors: Gasho E. , Kiseleva Alexandra , Temerov Andrey
Published: May 2022

The article has examined variants of combined heat supply systems development using solar panels and heat pumps in different climatic zones of Russia. The successful operation of renewable energy sources and heat pumps in Russia still depends on enthusiasts without government support. Rational use of combined and hybrid systems based on renewable sources of energy in these cases might quite possibly lead to more efficient solutions which result in different system`s multiplicative effects.
Electrical energy consumption optimization for fuel and energy complex facilities based on the fuzzy logic model and artificial neural networks
Authors: Rutskov Aleksey , Fedorov IAkov , Volkov Leonid
Published: May 2022

The model of electric power consumption dynamic at the fuel and energy complex has been suggested which possesses properties of forecasting and generation of control actions. The model operation is based on the combined fuzzy neuron networks. The model allows to increase the accuracy of indexes in estimating of future periods for optimization problems solution in comparison to the existing realizations based on regression models. The paper has determined the objective function of optimization on minimum losses of active power together with limitations typical for fuel and energy complex facilities; suggested modified Newton-Raphson algorithm based on fuzzy neuron networks; obtained efficiency assessment of the developed algorithms applied to the simulation models of FECF functioning for short-, medium- and long-term forecasting.
Energy and exergy study of Freon’s R1234yf, R1234ζε for a vapor compression heat pump unit
Authors: Boris Boris , Karnaukh Viktoriia , Biryukov Aleksey
Published: May 2022

This paper has carried out the study of the energy and exergy effectiveness of vapor compression heat pump system for hot water supply. Specific of the study is in the comparative analysis of heat pump systems efficiency which operates on refrigerants of third (hydrofluorocarbons HFC) and fourth (hydrofluoroolefins HFO) generation. The study results have proven the effectiveness of the refrigerant agents of HFO group use.
Development of software for photoelectric system calculation
Authors: Voskresenskaya Svetlana , Bekirov Eskender , Enina A.
Published: May 2022

The article presents the development of the software for photoelectric system calculation which can be used without pretraining. For this purpose, the requirements for software have been formulated and the algorithm of operation composed. The software is realized on JavaScript and the calculations for specific cases are presented.
Calculation of biogas and RDF cofiring
Authors: Trubaev Pavel , Kornilova Natalya
Published: May 2022

The paper suggests the calculation method of combustion when solid and gaseous fuels are cofired. The calculation is suggested to carry out per unit of heat output released during combustion but not per unit of mass or volume of fuel. The method has been tested for evaluation of greenhouse gas emissions during combustion of different fuel types and during waste and landfill gas cofiring. During coal and waste combustion, the CO2 content in products of combustion is around 0,05 m3/MW, for natural gas combustion - 0,028 m3/MW which is 1,8 times lower than for coal firing. During biogas combustion, the carbon dioxide content in the combustion products depends on the methane concentration in biogas and is around 0,04...0,06 m3/MW. The increased CO2 emission during biogas combustion in comparison to natural gas is explained by a high carbon dioxide content in biogas itself. Having in mind that biogas creates a significant greenhouse effect due to methane presence in it the landfill gas utilization, which would have been released into the atmosphere anyway, leads to greenhouse gas emissions decrease by 0,6...1,9 m3/MW of CO2 equivalent.
Solar heating supply of an individual home using an ice accumulating unit
Authors: Marinina Svetlana , Yavorovsky Yuriy , Sultanguzin Ildar
Published: May 2022

The paper has carried out the theoretical examination of the heating system and hot water supply system by using a heat pump which uses as a low-grade heat source a solar panel and ice accumulator. The paper presents the balance calculation of ice accumulation unit and pay-back period for ice accumulation unit, evaluation of the economic feasibility of unit operation by comparing it with the heat supply source alternatives that are commonly available.
Analysis of the efficiency of steam-organic technology with internal regeneration in the organic renkin cycle
Authors: Vorogushina Nadezhda
Published: May 2022

The article discusses the combination of steam-water and organic Rankine cycles, the positive effects of this technology, affecting the ecology and equipment service life. The expediency and efficiency of using the regenerator for different types of saturation curves for a group of organic liquids are considered.
Improvement of environmental conditions and safety of a metropolitan city by energy industrial complex modernization
Authors: Chekhranova Olga
Published: May 2022

This article analyses the current state of the heat and power complex in Krasnoyarsk city. It presents the developed measures for heat supply sources improvement, finding advanced sources, and calculation of their theoretical and practical thermal potential considering economic feasibility. There has been conducted the complex calculation and analysis of coordination between Krasnoyarsk heat supply and sources that use the secondary and low-grade heat.