bluuebunny/crossref_metadata_2025 huggingface dataset:
Overview of Plasmodium spp. and Animal Models in Malaria Research
Authors: Gozalo Alfonso S , Robinson Christen K , Holdridge Julie , Franco Mahecha Olga L , Elkins William R
Published: June 2024

Malaria is a parasitic disease caused by protozoan species of the genus Plasmodium and transmitted by female mosquitos of the genus Anopheles and other Culicidae. Most of the parasites of the genus Plasmodium are highly species specific with more than 200 species described affecting different species of mammals, birds, and reptiles. Plasmodium species strictly affecting humans are P. falciparum, P. vivax, P. ovale, and P. malariae. More recently, P. knowlesi and other nonhuman primate plasmodia were found to naturally infect humans. Currently, malaria occurs mostly in poor tropical and subtropical areas of the world, and in many of these countries it is the leading cause of illness and death. For more than 100 y, animal models, have played a major role in our understanding of malaria biology. Avian Plasmodium species were the first to be used as models to study human malaria. Malaria parasite biology and immunity were first studied using mainly P. gallinaceum and P. relictum. Rodent malarias, particularly P. berghei and P. yoelii, have been used extensively as models to study malaria in mammals. Several species of Plasmodium from nonhuman primates have been used as surrogate models to study human malaria immunology, pathogenesis, candidate vaccines, and treatments. Plasmodium cynomolgi, P. simiovale, and P. fieldi are important models for studying malaria produced by P. vivax and P. ovale, while P. coatneyi is used as a model for studying severe malaria. Other nonhuman primate malarias used in research are P. fragile, P. inui, P. knowlesi, P. simium, and P. brasilianum. Very few nonhuman primate species can develop an infection with human malarias. Macaques in general are resistant to infection with P. falciparum, P. vivax, P. malariae, and P. ovale. Only apes and a few species of New World monkeys can support infection with human malarias. Herein we review the most common, and some less common, avian, reptile, and mammal plasmodia species used as models to study human malaria.
Rodents Used for the Propagation of Hookworms and Haemonchus contortus
Authors: DeMarco George J
Published: June 2024

Helminthiasis due to hookworm infestations in humans and Haemonchus contortus in sheep cause untold levels of disease and economic losses worldwide. Drug resistance is an ever-growing problem with pathogenic helminths. Thus, there is a critical need for new treatment strategies for hookworms and H. contortus that depends on animal models. Because hookworms and H. contortus are obligate parasites, they can only be maintained using live animals. This review describes use of the Syrian golden hamster to propagate hookworms and Mongolian gerbil to propagate H. contortus.
Development of a Model of Tubulointerstitial Fibrosis Using Transient Unilateral Renal Ischemia and Delayed Contralateral Nephrectomy in Domesticated Cats
Authors: Lourenço Bianca N , Dickerson Vanna M , Brown Cathy A , Rissi Daniel R , Heathcote Jennifer M , Hare Jonathan E , Brown Scott A , Schmiedt Chad W
Published: June 2024

Tubulointerstitial fibrosis is a classic histologic feature of chronic kidney disease (CKD) in cats and a final common pathway toward end-stage renal disease. Domesticated cats have been used in models of ischemia-induced renal fibrosis. The objective of this study was to evaluate the performance of 2 variations of a transient unilateral renal ischemia and delayed contralateral nephrectomy model of tubulointerstitial fibrosis in cats. Purpose-bred, young adult, domesticated cats underwent 90 min of surgically induced ischemia to the right kidney followed by delayed contralateral nephrectomy performed 21 d (RI-CN21d group; n = 10) or 90 d postischemia (RI-CN90d group; n = 12). Control cats underwent sham surgery followed by left nephrectomy 21 d after (sham-CN group; n = 3). Renal functional parameters, including glomerular filtration rate and serum creatinine concentration, were evaluated before and after surgeries. The right kidneys were harvested 120 d postischemia/sham. Renal histology with lesion scoring and histomorphometry for quantification of smooth muscle actin immunolabeling and collagen staining were performed on harvested kidneys. Severe acute kidney injury prompted euthanasia after left nephrectomy in 5/10 (50.0%), 2/12 (16.7%), and 0/3 (0%) of cats in the RI-CN21d, RI-CN90d, and sham-CN groups, respectively. A significant decrease in glomerular filtration rate by day 120, relative to baseline, occurred in cats in the RI-CN21d group (P < 0.001) and RI-CN90d group (P < 0.001) but not the sham-CN group (P = 0.76). All but one cat in the ischemia groups were azotemic at the study end. Kidneys subjected to ischemia had higher interstitial inflammation, tubular atrophy, and fibrosis scores compared with sham-operated kidneys. There were significant increases in smooth muscle actin immunolabeling and collagen staining in these kidneys, relative to the contralateral kidneys. In summary, 90 min of unilateral renal ischemia and delayed contralateral nephrectomy induced histologic and biochemical changes consistent with CKD in cats. A 90-d period between ischemia and nephrectomy resulted in improved survivability of the model.
Overview and Approaches for Handling of Animal Models of Leishmaniasis
Authors: Suckow Mark A , Bolton Iris D , McDowell Mary Ann
Published: June 2024

Leishmaniasis, a disease of global relevance, results from infection with the protozoan parasite, Leishmania, which is transmitted to susceptible hosts through the bite of sand flies. Multiple forms of leishmaniasis may occur, including cutaneous, mucocutaneous, and visceral. Research with animal models remains an important approach to help define basic pathophysiologic processes associated with infection and disease. In this regard, mice and hamsters represent the most commonly used models. The severity of leishmaniasis in animal models depends on several factors, including genotype of the host and parasite and the dose and route of administration of the parasite to the host, and severity of outcome may range from subclinical to severe illness. This review provides basic background on leishmaniasis, relevant animal models, the pathophysiology and clinical signs in animals used as models of leishmaniasis, and general approaches to mitigate risk to personnel.
Endothelial Cell Dysfunction: Onset, Progression, and Consequences
Authors: Naderi-Meshkin Hojjat , Setyaningsih Wiwit Ananda Wahyu
Published: June 2024

Endothelial cell dysfunction is a complex process involving various causes, early and late events, and subsequent consequences. This review provides an overview of each aspect and outlines therapeutic interventions targeting these stages. Causes of endothelial dysfunction encompass a spectrum of risk factors including hypertension, diabetes, smoking, obesity, inflammation, oxidative stress, and genetic predispositions. Early events such as endothelial activation, inflammatory response, and dysregulated vasomotor tone precede late events like oxidative stress, endothelial apoptosis, and microvascular rarefaction. The consequences include endothelial remodelling, neovascularization, organ dysfunction, and clinical manifestations, highlighting the diverse impacts across multiple systems. While depicted linearly, the progression of endothelial dysfunction is dynamic, influenced by various factors such as the underlying cause and affected vascular bed. Understanding these dynamics is crucial for tailoring therapeutic interventions, ranging from lifestyle modifications to targeted therapies, to address the underlying causes and effects effectively. Here we provide comprehensive understanding of endothelial cell dysfunction that is essential for developing strategies to mitigate the impact of this dysregulation on health and cardiovascular diseases progression.
MGST1 May Regulate the Ferroptosis of the Annulus Fibrosus of Intervertebral Disc: Bioinformatic Integrated Analysis and Validation
Authors: Huo Zhenxin , Li Dawei , Zhang Kaihui , Yan Bingshan , Zhang Tongxing , Li Zhenhua , Huang Shengbo , Liu Yue , Xu Baoshan
Published: June 2024

Background: The objective of this research was to identify differentially expressed genes (DEGs) related to ferroptosis in the annulus fibrosus (AF) during intervertebral disc degeneration (IDD). Methods: We analyzed gene data from degenerated and normal AF obtained from the GSE70362 and GSE147383 datasets. An analysis to determine the functional significance of the DEGs was conducted, followed by the creation of a network illustrating the interactions between proteins. We further analyzed the immune infiltration of the DEGs and determined the hub DEGs using LASSO regression analysis. Finally, we identified the hub ferroptosis-related DEGs (FRDEGs) and verified their expression levels using Real-time quantitative polymerase chain reaction (RT-qPCR), Western blot, Immunohistochemical Staining (IHC), and Immunofluorescence (IF). Results: By analyzing the GSE70362 and GSE147383 datasets, we identified 118 DEGs. In degenerative AF groups, we observed a significant increase in immune infiltration of resting memory CD4+ T cells. LASSO regression analysis revealed 9 hub DEGs. The construction of a Receiver Operating Characteristic (ROC) curve yielded an Area Under the Curve (AUC) value of 0.762. Furthermore, we found that MGST1 is a hub gene related to ferroptosis. Our examination of immune infiltration indicated that MGST1 primarily influences macrophage M0 in different immune cell expression groups. Finally, our observations revealed a marked upregulation of MGST1 expression in the degenerated annulus fibrosus tissue. Conclusion: Our findings indicate an upsurge in MGST1 levels within degenerative AF, potentially playing a crucial role in the exacerbation of IDD. These findings provide a foundation for further exploration of the pathological mechanisms underlying IDD and offer potential drug targets for intervention.
Chronic Alcohol Exposure Alters the Levels and Assembly of the Actin Cytoskeleton and Microtubules in the Adult Mouse Hippocampus
Authors: Gao Da-Peng , Wang Lu-Wan , Xie Dong-Lin , Li Qiong , Yu Zhi-Peng , Tang Zi-Hang , Cui Ke-Ke , Cai Yu
Published: June 2024

Background: Alcohol abuse, a prevalent global health issue, is associated with the onset of cognitive impairment and neurodegeneration. Actin filaments (F-actin) and microtubules (MTs) polymerized from monomeric globular actin (G-actin) and tubulin form the structural basis of the neuronal cytoskeleton. Precise regulation of the assembly and disassembly of these cytoskeletal proteins, and their dynamic balance, play a pivotal role in regulating neuronal morphology and function. Nevertheless, the effect of prolonged alcohol exposure on cytoskeleton dynamics is not fully understood. This study investigates the chronic effects of alcohol on cognitive ability, neuronal morphology and cytoskeleton dynamics in the mouse hippocampus. Methods: Mice were provided ad libitum access to 5% (v/v) alcohol in drinking water and were intragastrically administered 30% (v/v, 6.0 g/kg/day) alcohol for six weeks during adulthood. Cognitive functions were then evaluated using the Y maze, novel object recognition and Morris water maze tests. Hippocampal histomorphology was assessed through hematoxylin-eosin (HE) and Nissl staining. The polymerized and depolymerized states of actin cytoskeleton and microtubules were separated using two commercial assay kits and quantified by Western blot analysis. Results: Mice chronically exposed to alcohol exhibited significant deficits in spatial and recognition memory as evidenced by behavioral tests. Histological analysis revealed notable hippocampal damage and neuronal loss. Decreased ratios of F-actin/G-actin and MT/tubulin, along with reduced levels of polymerized F-actin and MTs, were found in the hippocampus of alcohol-treated mice. Conclusions: Our findings suggest that chronic alcohol consumption disrupted the assembly of the actin cytoskeleton and MTs in the hippocampus, potentially contributing to the cognitive deficits and pathological injury induced by chronic alcohol intoxication.
Wide Spectrum of Bradyarrhythmias and Supraventricular Tachyarrhythmias in Sportsmen: Run Forrest, Run?!
Authors: Kampka Zofia , Drabczyk Mateusz , Piłka Nina , Orszulak Michał , Rycyk Maciej , Mizia-Stec Katarzyna , Wybraniec Maciej T.
Published: June 2024

The intricate relationship between sports participation and cardiac arrhythmias is a key focus of cardiovascular research. Physical activity, integral to preventing atherosclerotic cardiovascular disease, induces structural, functional, and electrical changes in the heart, potentially triggering arrhythmias, particularly atrial fibrillation (AF). Despite the cardiovascular benefits, the optimal exercise amount remains unclear, revealing a J-shaped association between AF and exercise. Endurance athletes, particularly males, face elevated AF risks, influenced by age. Risk factors vary among sports modalities, with unique physiological responses in swim training potentially elevating AF risk. Clinical management of AF in athletes necessitates a delicate balance between rhythm control, rate control, and anticoagulation therapy. Sport-induced bradyarrhythmias, including sinus bradycardia and conduction disturbances, are prevalent among athletes. Managing bradycardia in athletes proves challenging due to its complex and not fully understood pathophysiology. Careful consideration is required, particularly in symptomatic cases, where pacemaker implantation may be necessary for sinus node dysfunction. Although pacing is recommended for specific atrioventricular (AV) blocks, milder forms often prevail without restricting sports participation. This review explores the nuanced relationship between exercise and tachy- and bradyarrhythmia in athletes, addressing the challenges clinicians face when optimizing patient care in this distinctive population.
Profil Metabolik Rumen In Vitro Pakan Silase Kulit Ubi Kayu dari Berbagai Lama Penyimpanan
Authors: Raguati Raguati , Afzalani Afzalani  , Rahmi Dianita  , Yun Alwi  , Atika Oktaliza
Published: June 2024

This research aims to determine how long cassava peel silage can be stored while maintaining its fermentability in the rumen and its suitability as animal feed. The study was conducted at the Laboratory of Animal Nutrition and Forage, Faculty of Animal Science, University of Jambi. The material used in the research was cassava peel silage, molasses, EM4, and water. The study used a design with four treatments and five replications: P0 - silage without storage, P1 - silage stored for one week, P2 - silage stored for two weeks, and P3 - silage stored for three weeks. The variables observed in this study were pH, total gas, dry matter digestibility (DMD), organic matter digestibility (OMD), VFA, and microbial protein (MP). Data analysis was performed using the SPSS program, and if there was a significant difference between treatments, Duncan's test was carried out. The results showed that the treatment had a significant effect (P<0.05) on pH and an insignificant effect (P>0.05) on DMD, OMD, gas production, VFA, and microbial protein (MP). Based on the average results of the research, which were pH 6.25-6.71, DMD 66.47-72.19%, OMD 74.45-78.38%, total gas 69.00-76.80 ml, VFA 0.729-1.149 µM, and MP 481.080-526.220 mg/g. It can be concluded that cassava peel silage can be stored for up to three weeks without interfering with rumen metabolisms.
 
Key words: Cassava Peel Silage, Rumen Metabolism, Storage Time, In Vitro
 
ABSTRAK
Penelitian ini bertujuan untuk mengetahui seberapa lama penyimpanan silase kulit ubi kayu agar silase ini masih bisa dimanfaatkan sebagai pakan ternak yang tidak mengganggu fermentabilitas di rumen. Materi digunakan adalah silase kulit ubi kayu, kulit ubi kayu diperoleh dari pembuatan keripik ubi kayu. Bahan yang digunakan untuk pembuatan silase kulit ubi kayu pada penelitian ini adalah, molases, EM4 dan air secukupnya. Penelitian menggunakan Rancangan dengan 4 perlakuan 5 ulangan. P0 : Silase tanpa disimpan P1 : Silase disimpan selama 1 minggu P2 : Silase yang disimpan selama 2 minggu P3 : Silase yang disimpan selama 3 minggu. Peubah yang diamati pada penelitian ini terdiri pH, Total Gas, Kecernaan Bahan Kering (KcBK), Kecernaan Bahan Organik (KcBO), Total VFA (TFVA), ME dan Protein Mikroba (PM). Analisa data Data dianalisis dengan menggunakan program SPSS. Jika terdapat perbedaan antar perlakuan dilanjutkan dengan uji jarak Duncan (DMRT). Hasil penelitian ini perlakuan berpengaruh nyata(P<0,05) terhadap pH dan berpengaruh tidak nyata(P>,0,05) terhadap KcBK, KcBO, Produksi Gas, VFA dan Protein Mikroba. Rataan pH  6,25-6,71.; KcBK 66,47-72,194%; KcBO 74,45-78,38%; Total gas 69,00- 6,80 ml, VFA 0,729-1,149 µM; PM  481,080-526,220 mg/g. Kesimpulan penelitian ini silase kulit ubi kayu yang disimpan hingga 3 minggu tidak mengganggu metabolic rumen sehingga masih layak untuk dikonsumsi ternak.
 
Kata kunci: Silase Kulit Ubi Kayu, Metabolik Rumen, Lama Penyimpanan, In Vitro
Pengelolaan Sumberdaya Alam Pantai Batu Pinagut
Authors: Botutihe Nur Meyla Ulfiana
Published: June 2024

The research was carried out in Boroko Village, North Bolang Mongodow Regency with the aims of: (1) collecting data on natural resources on the Batu Pinagut coastline (2) Describing the potential for developing natural resources on the Batu Pinagut coastline (3) Analyzing policies on damage control. Determination of the sample using purposive sampling technique. Data was collected using observation, interview, documentation and document recording techniques. The results of the research show: (1) Batu Pinagut Beach has coastal resource potential that has been developed, namely biological resources and non-biological resources (2) management of coastal resources in Pemuteran Village includes tourism coral reef conservation in terms of tourism service training (3) Resource policy needs regulations are enforced, so that there is balance, preservation and continuity of resources. The rules do not apply to all areas, but to areas needed for the spawning and breeding of marine biota. To manage this area, it is necessary to have a conservation area that is equally understood and recognized by every stakeholder, stakeholders, fishermen, government, community and government. The rules and policies that are implemented involve stakeholders which become a culture that develops in society so that protection/conservation areas become a necessity and are implemented consciously by the community.
Keywords : Batu Pinagut Beach, Coastal Natural Resources
Internet of Things (IoT) dalam Estuarine Ecosystem: Kajian Bibliometrik
Authors: Oten Irvan
Published: June 2024

Kajian ini bertujuan untuk menganalisis dan menyelidiki literatur ilmiah yang berkaitan dengan penerapan Internet of Things (IoT) dalam konteks ekosistem muara. Ekosistem muara adalah lingkungan yang kompleks dan penting, yang sering kali menjadi titik fokus dalam upaya konservasi dan pengelolaan lingkungan. Dengan kemajuan teknologi IoT, terdapat potensi besar untuk menyatukan, mengelola, dan melindungi ekosistem muara dengan lebih efektif. Penelitian ini menyajikan hasil kajian bibliometrik dari 500 judul dengan kata kunci Internet of Things Estuarine Ecosystem pada sistem pencarian menggunakan Publish or Perish (PoP) dan VOS Viewer, menghasilkan meliputi tren penelitian, topik utama, dan menyembunyikan pengetahuan yang dapat menjadi panduan bagi peneliti yang tertarik dalam bidang Internet of Things (IoT). Tren penelitian yang berhubungan dengan kata kunci Internet of Things Ekosistem Muara diperoleh dalam 5 (lima) kata tren penelitian yaitu prediksi , pembelajaran mendalam ,  laguna, Sensor , Teknologi dan Informasi yang diharapkan dapat merangsang diskusi dan inovasi lebih lanjut dalam penerapan IoT untuk menjaga ekosistem ekosistem muara.
Kata Kunci: Internet of Things (IoT) , ekosistem muara, kajian bibliometrik
Chinese students' social experiences at a university in the United Kingdom
Authors: Zhang Yan
Published: June 2024

In UK universities, Chinese students make up the largest proportion of the international student population: Despite this, few qualitative studies have explored the socialization experiences of Chinese students; with research on Chinese students on one-year taught masters programmes being particularly scarce (Zhang, 2020). This paper explores how Chinese students on one-year taught master's programmes at UK universities experience socialization and what influences shape and affect their experiences. Two focus group interviews were conducted and thematic analysis was used to explore their experiences in depth. The two most important themes reported here are "Environmental factors influencing social experiences" and "Personal factors influencing the social experience‘’. Evidence from the focus group interviews suggests that environmental and personal factors shape the social experiences of Chinese students and that there is specificity, complexity and diversity in their experiences. This study contributes to helping Chinese students on one-year taught master's programmes in UK universities to have a better social experience and informs support measures in UK universities.
The Replication Dilemma: Potential Challenges in Measuring Replication Value—A Commentary on Isager, Van’t Veer, & Lakens (2024)
Authors: Fillon Adrien Alejandro , Chandrashekar Subramanya Prasad
Published: June 2024

The authors (Isager, Van‘t Veer, & Lakens, 2024) start with the main assumption that researchers' efforts toward replications are constrained by resources, and they propose a simple, practically scalable framework of research replication value that guides the researchers and the scientific community at large intending to achieve bigger bang for the buck. Specifically, the authors propose a framework that combines citation impact and sample size of the original articles as a metric for assessing replication value. This implies that original studies with higher scores on this metric can be prioritized for replication efforts. We thoroughly agree with the authors' assumption, and indeed support the view of working towards an optimal framework that helps the community achieve maximum research impact from the replication efforts. In this commentary, we propose to discuss three important limitations that have to be considered before using such metrics.
Emotional Intelligence of GPT-4 Large Language Model
Authors: Vzorin Gleb , Bukinich Alexey M. , Sedykh Anna , Vetrova Irina , Sergienko Elena
Published: June 2024

Current neural network models can demonstrate reasonable-looking behavior, considered by some developers and researchers human-like. For example, a large language model GPT-3 is susceptible to human-like cognitive biases. Yet there is no data of such models solving emotional intelligence (EI) tasks. They are connected to the abilities that has been previously considered as specifically human EI is an important aspect of human communication. The ability to understand and respond to emotional cues is essential for effective communication. Therefore, it is crucial to determine the ways AI models such as ChatGPT demonstrate EI. The present research aims to measure the EI of GPT-4, a large language model trained by OpenAI. Russian version of the Mayer–Salovey–Caruzo Emotional Intelligence Test sections B, C, D, F, G and H were used in this research. High points were obtained in Understanding emotions scale and Strategic EI. Mean points are obtained in Managing emotions scale. Low and less reliable values are obtained in Using emotions to facilitate thought scale. Thus, GPT-4 seems already capable of identifying emotions in text and describing techniques for managing them. However, complex cases and irregular situations requiring emotions qualitative analysis would be a hard task for GPT-4
Into the unknown: Maternal responsiveness influences young children’s support-giving expectations of fathers but not unfamiliar others.
Authors: Jia Chenglong , SHEN YUAN , Zhu Ling , Sun Li , Du Kelin , Qin Jinliang
Published: June 2024

Interactions with primary caregivers shape children’s expectations of interactions with others, but the mechanism is not clear yet. We included Han Chinese children aged 5–6 (N = 121, 61 boys) from a city in East China and tested their support-giving expectations of mothers, fathers, and unfamiliar others after observing mother-child interactions with different levels of maternal responsiveness. Across two studies, we found that children’s support-giving behavior and willingness expectations decreased significantly in the unresponsive condition for mothers and fathers but not for unfamiliar others. The results suggest that relationship type between children and interaction partners moderates the effects of maternal responsiveness on children’s expectations of partners’ support-giving. They shed light on how young children understand and represent interpersonal interactions.
Kulturen der künstlichen Intelligenz. AI Assemblages und die Transformationen des Alltags
Authors: Bareither Christoph
Published: June 2024

Artificial Intelligence is one of the keywords of our time, and AI systems are currently initiating numerous transformations in various areas of everyday life. How can cultural anthropology and “Empirische Kulturwissenschaft” at the interface with digital anthropology contribute to understanding these transformations and to shap-ing social and cultural negotiation processes around AI? To answer this question, this article develops the concept of AI assemblages, which aims to illuminate the dynamics of sociotechnical relations between human and more-than-human actors or compo-nents surrounding AI systems. Assemblage thinking allows to reflect upon and describe numerous “small” transformations of everyday life connected to AI without uncritically reproducing grand narratives of sociotechnical change and upheaval. On a more gen-eral level, analyzing AI assemblages is a way to study cultures of AI, that is, to study “a whole way of life” (Williams) in which routines, relationships, and cultural orders are increasingly shaped by AI systems. Three examples illustrate this perspective: AI as-semblages in memory culture (virtual survivor testimonies in Holocaust remembrance), in popular culture (social media and their algorithms), and in academic culture (gen-erative AI in academic research and teaching).
Literatura źródłem związków frazeologicznych. Słownik
Authors: Piela Agnieszka
Published: June 2024

Literature is one of the oldest sources of phraseology. In the Polish phraseological resource, and not only in Polish, but there are also expressive associations of writer's provenance, the roots of which date back to antiquity. Importantly, this source is still alive and open, as evidenced by new constructions of this type entering the social circulation. Connections formed under the influence of various literary texts represent a sparsely investigated aspect of the Polish phraseological stratum. So far, there has been no elaboration showing the richness of the discussed phraseologies and explaining their literary origin. The presented collection, containing a total of 140 units of language, fills this gap in Polish lexicography. The book delineates the connections documented within both general and specialized dictionaries, as well as elucidates relationships newly incorporated into this lexicon, such as "plume dance," "waiting for Godot," "Dantean scenes," "heart of darkness," "Kafkaesque situation," "rabbit relatives and friends," "to rejuvenate hearts," "lion's share," "small apocalypse," "Mrożek would not have invented it," "order of souls," "lonely white sail," "skin and bones," "shadow streak," "The Three Brothers Budrys," and "call of blood". In native linguistics, there lacks a distinct designation for fixed constructions with a literary lineage. Consequently, the author introduces the term "literatureism" and its classifications: "lexical literature" and "phraseological literature." The main purpose of the publication is to present the meanings and etymology of the indicated fragment of phraseology. Studying the literary origins of currently operative expressions appears crucial, as the rationale behind many of them becomes increasingly obscure to users of the Polish language. Consequently, there exists a risk of their eventual obsolescence.
PROGRAM KEMITRAAN KELOMPOK MASYARAKAT UNTUK MENCEGAH DAN MENGONTROL HIPERTENSI DENGAN EFFLEURAGE BACK MASSAGE DI PUSKESMAS SANANWETAN KOTA BLITAR
Authors: Sepdianto Tri Cahyo , Suprajitno Suprajitno , Ciptaningtyas Maria Diah
Published: June 2024

Hipertensi merupakan penyakit tidak menular dengan kasus yang terus mengalami peningkatan tiap tahunnya. Deteksi dini hipertensi dan pengelolaan hipertensi melalui pola aktivitas dan nutrisi serta managemen non farmakologi lainnya seperti effleurage back massage sangat penting untuk mengontrol tekanan darah pada penderita hipertensi. Tujuan pengabdian ini untuk meningkatkan pengetahuan dan ketrampilan kader dalam mencegah dan mengelola hipertensi. Metode yang digunakan adalah pemberdayaan Masyarakat melalui kegiatan penyuluhan tentang hipertensi, deteksi dini dan pengelolaan hipertensi serta pelatihan managemen non farmakologi dengan effleurage back massage untuk mengontrol tekanan darah pada penderita hipertensi. Kegiatan diikuti oleh 25 kader POSBINDU PTM di wilayah Puskesmas Sananwetan Kota Blitar. Hasil kegiatan menuunjukkan terjadi peningkatan pengetahuan kader dalam mencegah dan mengelola hipertensi. Ketrampilan kader dalam mangemen non farmakologi melalui effleurage back massage juga mengalami peningkatan.  Effleurage Back Massage merupakan salah satu managemen non farmakologi yang dapat diterapkan dengan mudah olek kader POSBINDU PTM kepapada pasien hipertensi untuk mengontrol tekanan darah dan mencegah komplikasi.
Ecological footprint and the wealth of people from a socio-ecological point of view
Authors: Mulyawan Muhammad Fathurrahman , Antriyandarti Ernoiz , Son Ho Ngoc
Published: June 2024

With time it is getting more difficult to solve environmental issues as several people are unaware of the current environmental concerns. Using the ecological footprint analysis, people can know their daily use of natural resources. Therefore, this study aims to determine the ecological footprint of people in Solo, Indonesia. We applied the Ecological Footprint Test to the 152 respondents that consist of students, academicians and ordinary people. Through survey and questionnaire, this study found the relationship between different statuses of occupation and determined which category was more eco-friendly. Furthermore, this study hypothesized about the effects of education level on the use of natural resources and explained that educational level does affect the use of natural resources. Regression analysis was used to examine the determinant of ecological footprint score of the Solo people. The result showed that the estimated parameter of education has positively significant to the ecological footprint of the people of Solo. The higher the education, the higher the ecological footprint score of the Solo people. This is indirectly related to mobility and the goal of earning more income for those with higher education. Therefore, their consumption of natural resources is higher than that of ordinary people. TheÂ  economic improvement is directly proportional to increases in income and natural resources.JEL ClassificationÂ P18; Q01; Q30To cite this article: Mulyawan, M. F., Antriyandarti, E., & and Son, H. N. (2024). Ecological footprint and the wealth of people from a socio-ecological point of view. Journal of Socioeconomics and Development, 7(1), 14-23. https://doi.org/10.31328/jsed.v7i1.4218
The role of social variables on growth in South of Sumatera: A dynamic panel data analysis
Authors: Meilinda Riska Putri , Kurniawan Mahrus Lutfi Adi
Published: June 2024

Policy makers in all countries have an orientation towards economic growth and identify the factors that influence growth. This study applies social variables in the economic growth model, this is inseparable from the views of classical and neoclassical economists that human resources play an important role in economic growth. The research gap is applying short-term and long-term estimates of social variables to the economic growth model in South Sumatra Province. Research using dynamic panel data on the GMM system. The results showed that the human development index (HDI) as a proxy for human capital has a positive effect on economic growth in the short and long term, another result, the labor force, unemployment and poverty consistently have a negative effect on growth in South Sumatra Province in the short and long term. The implication of this research is to improve the quality and quantity of education and health facilities and policy for education to improve cognitive skills because it can produce a labor force with high skills. Sustainable fiscal policy and pro-poor visions and encouraging investment to create more jobs.JEL ClassificationÂ C31; I25; H75To cite this article: Meilinda, R. P., & Kurniawan, M. L. A (2024). The role of social variables on growth in South of Sumatera: A dynamic panel data analysis. Journal of Socioeconomics and Development, 7(1), 68-76. https://doi.org/10.31328/jsed.v7i1.4984
Price fluctuations and market integration of fresh skipjack tuna in Indonesia
Authors: Rahim Abd. , Hastuti Diah Retno Dwi , Malik Abdul , Sabar Wardihan , Irwandi Irwandi
Published: June 2024

Price fluctuations significantly impact the market integration of fresh skipjack tuna. This study employed quantitative methods, analysing time-series data sourced from publicly available secondary outlets. Skipjack price fluctuations were estimated through multiple regression analysis, while skipjack market integration was assessed using the Index of Market Connection (IMC). The research findings indicate that skipjack tuna prices in Indonesia, at the retail, wholesale, and producer levels, are positively influenced by past fluctuations in skipjack prices. However, changes in skipjack prices at the wholesale level do not directly affect retail prices. In the short term, there is relatively high market integration between producer and wholesale markets, as well as between wholesale and retail markets. Producers and wholesale markets function as price-makers, while there is relatively low market integration between the producer and retail markets, where producers act as price-takers. For the market to function optimally, it needs to be wholly interconnected. In the long run, there is no integration in the skipjack market. Efficient marketing distribution requires improved access to infrastructure, including roads, land, and sea transportation. Furthermore, the establishment of a digital marketing system is essential for obtaining quick information on the prices of fishery products, spanning from producer markets, such as fish auctions, to wholesale and retail markets.JEL ClassificationÂ D82; Q11; Q22To cite this article: Rahim, A., Hastuti, D. R. D., Malik, A., Sabar, W., & Irwandi (2024). Price fluctuations and market integration of fresh skipjack tuna in Indonesia. Journal of Socioeconomics and Development, 7(1), 1-13. https://doi.org/10.31328/jsed.v7i1.5085
Sustainability analysis and development strategy of crystal guava tourism: An evidence from Bojonegoro Regency, Indonesia
Authors: Hartono Rio Cahyo , Efani Anthon , Susilo Susilo
Published: June 2024

Tourism in Indonesia holds immense potential for bolstering national income and fostering economic growth. Agrotourism, an emerging sector, intertwines tourism activities with agriculture, exemplified by the guava crystal orchads in Padang Village, Bojonegoro Regency. Despite its promise, the full potential of this agrotourism destination remains untapped. A mixed-method approach was employed in a study to assess its sustainability comprehensively. Quantitative data was initially collected and analyzed using multidimensional scaling (MDS), followed by SWOT analysis. Findings indicate that while the ecological dimension demonstrates strong sustainability, other aspects such as the economy exhibit room for improvement. Consequently, various sustainability formulation strategies are proposed. The S-O strategy advocates collaboration with external stakeholders under favorable terms, while the W-O strategy emphasizes heightened promotional efforts and collaborative ventures to enhance human resource quality. Moreover, the S-T strategy entails intensifying promotional activities to counter competitors, whereas the W-T strategy focuses on enhancing accessibility, diversifying product offerings, and fostering collaborations to tackle challenges effectively. Implementation of these strategies is anticipated to furnish managers and policymakers with a pragmatic framework to enhance the sustainability. In essence, stakeholders can propel the crystal guava orchard agrotourism towards greater sustainability, thereby contributing significantly to the economic advancement of the region.JEL ClassificationÂ A14; Q26; Z30To cite this article: Hartono, R. C., Efani, A., & Susilo. (2024). Sustainability analysis and development strategy of crystal guava tourism: An evidence from Bojonegoro Regency, Indonesia. Journal of Socioeconomics and Development, 7(1), 77-88. https://doi.org/10.31328/jsed.v7i1.5440
Rural Tourism as a Tool for Sustainable Development of the Srem District in Serbia
Authors: Kosanović Nada , Bartula Mirjana
Published: June 2024

The beginning of the twenty-first century is characterized by nu­merous changes in all areas of life. These changes give us the right to antici­pate some global trends in the field of economy and business of the popula­tion in rural areas. Contemporary trends in the field of business in rural areas actualize tourism as the most important component of integral rural devel­opment and indicate that significant changes are expected in that area. The twenty-first century will be a period in which the needs and expectations of domestic and foreign demand will become increasingly refined, therefore it will be necessary for rural tourism to represent a combination of different as­pects and a value perception of the presentation of rural life. Family farms will be differentiated by the success of product and area branding, while intan­gible marketing assets such as brands, market knowledge, relationship with customers, and distribution coverage, will become a significant value of the region. The main goal of the research is to assess the potential and opportuni­ties for the development of a new program of rural tourism in the Srem District in Serbia based on sublimated and analyzed indicators for seven municipal­ities, which will contribute to the affirmation and development of rural tour­ism in the region.has been a decline in overnight stays and accommodation in Bulgaria. There is a recovery trend after the COVID-19 pandemic and a slight increase in both indicators. Revenue from overnight stays increases after 2020. There is a promising trend related to the development of the tourism sector.
Archaeological Sites and Local Renaissance: Enlightening Italy’s Inner Rural Areas – The Case Study of the 21 Villages in the Madonie Park, Sicily
Authors: Lombardo Luisa
Published: June 2024

In Italian inner rural areas, archaeology emerges as the thread that connects past and present, revealing the cultural and historical roots of often overlooked small villages. These settlements, like the Madonie District and its 21 villages, nestled in picturesque landscapes, hold archaeological treasures that, if properly rehabilitated and valorized, can trigger a social, economic, and cultural revival. Archaeology can play a pivotal role in reigniting the vi­tality of these communities with the contribution of technological innovation. Using augmented and virtual reality and emerging technologies, it is possible to immerse oneself in antiquity and have immersive experiences that allow the perception of inner rural areas history in new ways that revitalize existing sites but also enable the experience of what no longer exists, digitally recon­structing structures and realities lost over the centuries. This can attract visi­tors eager to uncover the authentic charm and intrinsic history of these places and can transform them into smart villages.
Art Nouveau Style as a Discursive Strategy for Tourism Promotion. The Case of the City of Oradea
Authors: Porumb Andra-Teodora , Oniţa Adina Săcara , Benea Ciprian-Beniamin
Published: June 2024

The paper analyzes how the Art Nouveau style has become a pri­mary element of tourism promotion and the brand of the City of Oradea, a city with a rich history and cultural tradition located on the western border of Romania, as well as the importance it occupies in building the image of this tourist destination and the city’s identity. With a unique architectural her­itage, the city of Oradea has become the most important Art Nouveau city in Eastern Europe, currently competing with famous cities such as Nancy, Barce­lona, Brussels, and Vienna and aspires to the status of a predilection destina­tion, to become a place tourists dream of. The speech that outlines the image of this destination is impregnated with marks of subjectivity; it appeals to ele­ments of history, tradition, culture and music, creating bridges between peo­ple and building an effective relationship with potential tourists.
Strength in Transition: Resilience of Sustainable Energy vs. Fossil Energy
Authors: Dias Rui , Chambino Mariana , Alexandre Paulo
Published: June 2024

Promoting clean energy sources necessitates global cooperation through cross-border collaboration, knowledge sharing, and resource alloca­tion. A global imperative exists to transition towards a cleaner, sustainable en­ergy mix to combat climate change and maintain environmental equilibrium. This study assesses the influence of fossil energy prices (Brent Crude Spot, WTI, FTSE 350 Oil, Gas & Coal, EURO STOXX Oil & Gas) on sustainable energy prices (Geothermal Index, Solar Energy Index, NASDAQ OMX Bio Clean Fuels Index, Wind Energy Index, WilderHill Clean Energy Index) in both stable and turbu­lent market conditions. This study suggests that sustainability and innovation in green energy significantly impact fossil fuel-related indexes. During chal­lenging periods, sustainable energy markets gain prominence, while “dirty” energy indexes exhibit varying degrees of influence. Remarkably, the Wilder­Hill Clean Energy Index plays a central role in shaping both fossil fuel and sus­tainable energy indexes. These findings underscore the growing trend to­wards greener and more sustainable investments, emphasizing sustainabili­ty’s substantial sway over financial markets.
Implementation of Next-Generation Firewalls in Modern Networks
Authors: Pavlović Milan , Zajeganović Marija , Milivojević Milan
Published: June 2024

The primary function of any firewall is to assist in protecting against unwanted or malicious traffic entering or leaving a network. How­ever, as threats evolve and become increasingly challenging to detect, net­work security must remain equally sophisticated. In addition to access control, Next-Generation Firewalls can block modern threats such as advanced mal­ware and application-layer attacks. This paper will present the fundamen­tal characteristics of Next-Generation Firewalls and their implementation in modern networks, particularly their use in IoT. First, the concept of Next-Gen­eration Firewalls will be explained, highlighting significant improvements they have over previous generations of firewalls, and the reasons for imple­menting them. Next, the authors will provide an overview of Next-Generation Firewall architectures. Special attention will be given to the use of Next-Gen­eration Firewalls in the context of IoT.
Strategic Integration of E-commerce and Franchising
Authors: Manaresi Angelo
Published: June 2024

The primary objective of this article is to discern the strategy im­plications arising from the incorporation of e-commerce by franchisors with­in franchise networks. Following interviews with key informants, an experi­ment was conducted to investigate the franchisees’ willingness to continue investing in the franchise network after the franchisor introduces an e-com­merce platform that excludes them. The long-term repercussions of inte­grating e-commerce into franchising networks include a diminished willing­ness among franchisees to sustain their investments. This may differ from the short-term acceptance of the franchisor’s e-commerce initiative, primarily at­tributable to the substantial power imbalance between franchisor and fran­chisee, as well as short-term inertia inherent in relation-specific investments and franchise contracts. A significant challenge faced by franchisors is the choice between establishing a profit-sharing model or, ideally, a mutually beneficial win-win arrangement with franchisees. Alternatively, the strategy may consider allocating more resources to directly operated stores.
Civil Servant Status and Labor Relations
Authors: Çukaj (Papa) Lirime , Pekmezi Iris , Miha Elsa
Published: June 2024

Albania, as a signatory of the Stabilization and Association Agreement, is legally obligated to meet European standards, even for pub­lic administration. This modest work attempts to provide a regulatory over­view of the status of public administration employees, the impact of politi­cal forces on sustainability, and the continuity of employment relationships of civilian servants. The primary goal of the entire regulatory system governing the status of civil servants is to establish uniform regulation for all positions related to the ex­ercise of public authority and responsibility for safeguarding the overall in­terests of the state. Simultaneously, it aims to strengthen legal protection, impartiality of civil servants, political independence, job stability, profes­sionalism, efficiency, and the optimal protection of individual rights and le­gitimate expectations of citizens from public administration. This work seeks to highlight these elements as reflected in Law No. 152/2013, as amended, also bringing to light the shortcomings or issues related to the implementation of this law. In the paper, an evolution of public administration has been reflected up to the present day, highlighting the issues related to recruitment, and move­ments within and outside public institutions. Efforts to establish sustainabil­ity in administrative positions through career progression, and staff moti­vation based on job performance, which should be objective and serve the purpose for which such a system has been established, are discussed. We have also endeavored to address these elements related to the status of civ­il servants in this work.
A Systematic Literature Review of Malcolm Baldrige National Quality Award (MBNQA)
Authors: Dima Thaleia , Glykas Michael
Published: June 2024

Many organizations measure and assess organizational perfor­mance as a business excellence strategy and make quality a key element of their overall business philosophy, as quality leads to improved business per­formance. In an increasingly turbulent and competitive business environ­ment, numerous organizations have adopted business excellence frame­works to obtain and monitor progress toward business excellence. Devel­oped in the USA, the Malcolm Baldrige Award is a prominent award con­cerning quality management. This paper reviews approximately 90 jour­nals from different countries, and most of the researchers use the criteria of the Malcolm Baldrige National Quality Award (MBNQA) to gauge organi­zational performance. The paper aims to present the Malcolm Baldrige Na­tional Quality Award (MBNQA) and compare it with even two well-known business excellence models in the world: the Deming Prize and the European Foundation for Quality Management (EFQM) to show what criteria the au­thors can apply to enhance Business Excellence Models (BEMs).