bluuebunny/crossref_metadata_2025 huggingface dataset:
India’s National Rural Health Mission (NRHM): Examining the Scope and Impact
Authors: Maimuna Maimuna , M Sameer Babu
Published: December 2024

Background: The National Rural Health Mission (NRHM), initiated in 2005, seeks to enhance access to healthcare and improve health outcomes for rural communities in India, explicitly emphasising maternal and child health.

Objective: This article assesses the National Rural Health Mission‘s effects on child development, focusing on significant initiatives like promoting institutional births, immunization efforts, and community involvement through Accredited Social Health Activists(ASHAs).

Method: By examining various studies and reports, this research highlights its objectives, functioning, major schemes and notable advancements in child health metrics, including declines in infant mortality rates (IMR) and rises in vaccination coverage. Nonetheless, issues such as insufficient infrastructure and high out-of-pocket costs persist.

Results: The results indicate the need for integrating child health initiatives within more extensive public health strategies to guarantee sustained development and better health outcomes for children in rural regions. National Rural Health Mission is one of the significant health related initiatives of Govt. of India. The National Rural Health Mission (NRHM) is a strategic initiative aimed at improving the health outcomes of rural communities through a comprehensive and inclusive approach. The mission’s core objectives focus on reducing maternal morbidity and child mortality, ensuring equitable access to affordable healthcare services, and strengthening primary healthcare systems to make medical care universally accessible. It also prioritizes the prevention and management of both communicable and non-communicable diseases through integrated healthcare delivery. Additionally, the NRHM emphasizes stabilizing population growth while addressing critical areas such as maternal and child health, adolescent health, and family planning, thereby fostering holistic and sustainable health development in rural areas.
Enhancing Grade 1 Pupils’ Classroom Engagement Through the Use of Zoology-Imagery Approach in Teaching Mathematics
Authors: Hornido Renie Carl R. , Baluyos Genelyn R. , Adolfo Crisfer A.
Published: December 2024

Mathematics has long been recognized as one of the most challenging subjects in education. The Philippines has consistently shown low performance in global Mathematics assessments, as the 2018 Programmed for International Student Assessment (PISA) highlights. This study examined the effectiveness of the Zoology-Imagery Approach in teaching mathematics to enhance classroom engagement among Grade 1 pupils in a public elementary school in Ozamiz City, Misamis Occidental, during the academic year 2023-2024. Using classroom- based action research, 31 pupils were selected through purposive sampling. Data collection involved a researcher-made test, and statistical analysis included mean, standard deviation, t-test, and thematic analysis. Results showed that the Zoology-imagery approach in teaching mathematics subject was a highly effective teaching strategy and has demonstrated a significant impact in enhancing pupils’ classroom engagement and involvement. Furthermore, the zoology-imagery approach significantly improved classroom engagement and motivation to learn mathematics and fostered pupils’ mathematical power. It is recommended to integrate this approach into educational practices to enhance pupils’ engagement, academic performance, and learning outcomes.
Views of Teachers Towards Use of Dialogue and Argumentation in the Mathematics Classroom
Authors: Munyati Lovemore
Published: December 2024

In the realm of Mathematics education, the use of dialogue and argumentation as pedagogical approach has gained significant attention in recent years. Research shows that the views of the teachers in the use of dialogue and argumentation teaching approach play a crucial role in shaping the learning experience for students. Therefore, the purpose of this study was to investigate the views of teachers towards use of dialogue and argumentation in the Mathematics classroom. The study employed a quantitative approach that used structured questionnaire for data collection from a sample of 100 Mathematics teachers selected from 72 secondary schools in Gutu district of Masvingo Province in Zimbabwe using a judgemental or purposive (non-probability) sampling strategy. Two statistical metrics namely the mean and the standard deviation were used for data analysis. Results of the study show that there is a general agreement among teachers that dialogue and argumentation is an effective approach to the teaching Ordinary level Mathematics. The main study limitation is that it only used a quantitative approach, which may have affected the depth and breadth of data collected about the views of teachers towards use of dialogue and argumentation in the mathematics classroom. The results of this study have implications on both practice and policy about the views of teachers towards use of dialogue and argumentation in the Mathematics classroom.
The Untold Stories of Green Marketing: Combating Greenwashing and Promoting Genuine Sustainability
Authors: Aragon Kristine Ann P. , Dioso Christine Joy B. , Melliza Geraldine Dimple P.
Published: December 2024

This research aims to analyse the processes of green marketing, that is the simultaneous occurrence of genuine sustainable marketing and the phenomenon of ‘greenwashing’ in consumer markets. Since the awareness of environmental issues increases, green marketing is becoming more popular in its strategies. Nevertheless, greenwashing or a situation in which companies make misleading statements to give a positive image of the environmental friendliness they are not, hinders consumer confidence, and undermines the genuine ESG approaches. Furthermore, the study highlights the role of managing transparency and the process of authenticating the communication message with the intention of increasing consumers’ confidence in their purchase decisions. Finally, it offers a practical course of action for firms and institutions combating the dangers of greenwashing and fostering the development of more rigorous sustainable practices in the market.
Old rats are not inferior to young ones in their ability to adapt to repeated sequential exposure to copper sulfate pentahydrate
Authors: Bozhkov Anatoly , Akzhyhitov Rustam , Dobrianska Nataliia , Bozhkov Аndrii
Published: December 2024

Abstract. The quality and longevity of life depend on the ability of a biological system to adapt to the continuously changing environmental factors. However, why the success of adaptation varies among individuals and whether there are differences in adaptive reserves between young (3 months old) and aged (20 months old) animals remains unclear. To address these questions, we investigated the relationship between the temporal characteristics of exposure (sequential injection of different doses of copper sulfate pentahydrate, CuSO₄*5H₂O) and adaptive success in young and aged Wistar rats. In addition, the potential to enhance adaptive capacity by a biologically active substance based on exometabolites of Pleurotus ostreatus and Saccharomyces cerevisiae (referred to as the "mix- factor") was evaluated. Adaptation success was assessed using Kaplan–Meier survival analysis and haematological and biochemical homeostasis parameters in surviving animals, 1.5 months after exposure to an increased dose of CuSO₄*5H₂O (0.50 mg/g liver). We found that rats exposed to repeated sequential doses of CuSO₄*5H₂O at a pre-adaptive concentration of 0.23 mg/g liver (33% of the lethal dose), followed by an increased dose, fall into three groups based on their capacity to adapted to the toxic effects successfully. The haematological and biochemical parameters of successfully adapted animals did not differ significantly from those of control animals. Furthermore, the temporal pattern, i.e., the number of pre-adaptation exposures to low doses, influenced resistance to the effects of higher compound doses, indicating hormesis. Aged rats exhibited an adaptive capacity comparable to young rats, demonstrating the ability to undergo hormesis and adapt to the increased dose of CuSO₄*5H₂O. The biologically active "mix- factor" (administered to rats after exposure to pre-adaptive doses of CuSO₄*5H₂O) had a minimal effect on the proportion of aged animals successfully adapting to the subsequent increased dose of CuSO₄*5H₂O, compared to the group of young rats.
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Keywords: age, hormesis, adaptation, pre-adaptation, copper sulfate pentahydrate
Producción agrícola colombiana: variables y factores de anticipación estratégica
Authors: Bolaños-Núñez José Medardo , Osorio-Isaza Vladimir
Published: December 2024

El artículo ofrece una exploración detallada de las variables que influyen en la producción agrícola en Colombia con un enfoque en la anticipación estratégica; esto, a través de la búsqueda de literatura académica y científica, que permitió identificar y analizar las variables teóricas, intermedias y empíricas relevantes en el estudio del sector agrícola. En primer lugar, se revisan las variables teóricas fundamentales que proporcionan el marco conceptual para entender la producción agrícola y la anticipación estratégica; a continuación, se exploran las variables intermedias, que actúan como mediadoras entre la teoría y la práctica, facilitando la comprensión de los mecanismos subyacentes que influyen en el sector agrícola colombiano; finalmente, se examinan las variables empíricas específicas, que permiten una comprensión más concreta de la realidad agrícola del país y su capacidad para anticipar y gestionar los riesgos. Como reflexiones se tiene el análisis enfocado a la comprensión de estas variables y factores que interactúan entre sí y con el entorno ambiental, influyendo en los procesos de toma de decisiones y planificación en el sector agrícola. Se concluye la importancia de una visión integral y estructurada de las variables y factores de anticipación estratégica para informar y orientar la toma de decisiones y políticas que promuevan un desarrollo agrícola sostenible y resiliente en el país.
A reduced-bias weighted least squares estimation of the extreme value index
Authors: Ocran By E , Minkah R. , Doku-Amponsah K.
Published: December 2024

In this paper, we propose a reduced-bias estimator of the EVI for Pareto-type tails (heavy-tailed) distributions. This is derived using the weighted least squares method. It is shown that the estimator is asymptotically unbiased, asymptotically consistent and asymptotically normal under the second-order conditions on the underlying distribution of the data. The finite sample properties of the proposed estimator are studied through a simulation study. The results show that it is competitive to the existing estimators of the extreme value index in terms of bias and Mean Square Error. In addition, it yields estimates of g > 0 that are less sensitive to the number of top-order statistics, and hence, it alleviate the problem of selecting an optimal tail fraction to some extent. The proposed estimator is further illustrated using practical datasets from pedochemical and insurance.
From high to low
Authors: IJsselstijn Marcel , Zomer Jeroen
Published: December 2024

In this article the authors draw on three case studies in testing the merits of an alternative peatland reclamation model – namely, from high to low – put forward by several authors in recent years. According to this new model, the drainage of the peatlands started from peat mounds built on top of the dried out peatland, rather than by digging ditches from natural waterways (low) to the centre of the peatland (high). Archaeological and other data for all three case studies – IJsselmonde, Roderwolde and Zeevang – have been analysed as systematically as possible. Roderwolde qualifies as a kind of comparative study. It, too, was considered indicative of an alternative reclamation model but, thanks to extensive archaeological research, we have a fairly detailed picture of this reclamation. In short, it proceeded in accordance with the established model and the peat mounds are a secondary phenomenon. Based on an analysis of the data for IJsselmonde and Zeevang, we conclude that there is as yet no evidence to support the existence of an alternative model. In fact, although the data are incomplete, the drainage methods appear to be consistent with the established model. As in Roderwolde, the peat mounds are a secondary phenomenon: they were created at a time when the peatlands had already subsided considerably as a result of drainage, but large-scale embankment building had not yet taken place.
Natural Pain Relief : Herbal Dark Chocolate For Menstrual Pain
Authors: Geeta R. Zine  , Samruddhi M. Deokar  , Sagar A. Kirtane  , Snehal J. Mhase
Published: December 2024

Individuals have a greater affinity for chocolate than for any other type of food, yet they often have a dislike for medications. Consequently, the objective of this study was to create a chocolate infused with herbal components, specifically designed to alleviate menstrual cramps. Primary dysmenorrhea (PD) is a common problem among women in their reproductive years that can negatively impact their quality of life. About 55% of women experience dysmenorrhea. One of the foods that can reduce menstrual pain is dark chocolate. Other herbal ingredients such as ginger, termeric, mint leaves, almond, cinnamon and honey are also known to reduce pain. However, research on combination of dark chocolate with herbal ingredients has not been conducted. Therefore, this study aims to determine the effectiveness of dark chocolate with herbs in reducing menstrual pain. Dark chocolate can be used as an alternative to overcome pain during menstruation time because it contains many benefits in the health sector. Chocolate contains copper which used by the body to synthesize collagen and neurotransmitters called endorphins. Endorphin hormone would be a analgesic and natural sedative so as to reduce the intensity of pain such as menstruation pain. Dark chocolate contains more cocoa, making it the best choice to get the health benefits. A physiochemical analysis was conducted on herbal chocolate to identify the presence of proteins, carbohydrates, and glycosides, which indicate the existence of various biomolecular components within the chocolate. This makeschocolate a non-pharmacological alternative for alleviating dysmenorrhea.The purpose of this study was to investigated the influence of dark chocolate on reducing mentrual pain in primary dysmenorhea.
Detection of Synthetic Audio Using MFCC Features and Machine Learning Techniques
Authors: S. Sinduja  , N. Narmadhavarshini  , S. Yasotha
Published: December 2024

Deepfake content, generated or modified using advanced AI to mimic authentic media, spans across audio, video, images, and text, presenting escalating challenges in detection due to its increasing realism. Recent research has focused on addressing this issue using the Fake-or-Real dataset, a comprehensive benchmark for detecting deepfake media. By leveraging machine learning algorithms, researchers have demonstrated promising advancements in identifying deepfake audio, with the VGG-16 model achieving notable accuracy in feature extraction and classification tasks. Furthermore, support vector machines (SVM) and gradient boosting models have shown exceptional performance on specific subsets of the dataset, effectively distinguishing between real and synthetic audio. These findings highlight the potential of combining robust datasets and advanced algorithms to counter the growing threat of deepfake media in diverse applications.
A Review on Plant Monitoring System using ESP8266
Authors: Bhoomika C  , Ankith I N  , Karthik S Kashyap  , Karthik  , Dr. Ganesh V N
Published: December 2024

Every nation has engaged in agriculture for a very long time. The science and skill of growing plants is called agriculture. The main factor in the rise of sedentary human civilization was agriculture. Agriculture has always been done by hand. Since the world is moving toward new technology and applications, it is imperative that agriculture follow suit. However, there are currently obstacles in agriculture as a result of rural-to-urban migration. Therefore, we have suggested an IOT and smart agriculture solution to address this issue. Agriculture, which is considered a science and a skill of plant cultivation, has been practiced throughout history in every nation. Technology is evolving in today’s world, and agriculture must likewise keep up with the times. A key component of smart agriculture is IoT. Sensors from the Internet of Things (IoT) are utilized to supply the data that is required for agricultural areas. Using wireless sensor networks to monitor agriculture and gather data from multiple sensors placed at different locations and transmitted over wireless protocols is the primary function of the Internet of Things. Node MCU powers smart agriculture through the use of IoT systems. The increasing demand for effective water management in agriculture in recent years has drawn a lot of attention to smart farming systems. Water use, crop output, and sustainability have all increased as a result of the integration of Internet of Things (IoT) technologies with farming systems, which has created new opportunities for real-time monitoring and control. The farming system uses the PIR (Passive Infrared Sensor) to identify the presence of animals nearby. Determining the soil’s water content is mostly dependent on the soil and moisture sensor. By keeping an eye on the outside temperature, the temperature sensor offers important information about the surrounding environment. IoTbased smart agriculture is a cutting-edge method of farming that makes use of technology to maximize agricultural productivity. Manual labor and antiquated methods, which were frequently labor-intensive and ineffective, were key components of the conventional agricultural approach.
Review on Preparation and Evaluation of Herbal Hair Tonic
Authors: Mrs. Sanskruti Shantaram Sapate  , Prof. Dr. Akshay M. Kasambe
Published: December 2024

These days, people are interested in hair preparation and conditionar materials such as hair tonic, shampoos, hair gel, hair tonic spray, conditioners formulations containing herbal extracts. Hair tonic is a product used to style or fashion the hair. The objective of gift examine study involves preparation of herbal hair tonic with aid of the using coconut oil, hibiscus, aloe vera, amala, tulsi, reetha, jojoba oil, rosemary oil and its evaluation for antibacterial, antifungal and strengthness of activity. The final instruction of these ingredients is formulated in batches with alternate in concentration. Every formulation is tested right effects for antifungal, antibacterial and strengthness of hair activity. The formulation having different concentration were characterised for proximate analysis such as acid insoluble ash, good consistency properly spreadibility, Ph, water, soluble ash, insoluble ash, homogeneity, appearance.
Hair is crown for the everyone because functions for hair providing protection, warmth, beauty and the support. Loss of hair is a universal most serious problem for everyone. That has been estimated to affected between 0.2 and 2% the world population. This study aimed involves preparation of herbal hair tonic from virgin coconut oil extract of a mix of nine herbs which is important or benifecial as herbal hair tonic
A Review on Detection of Nutrients of Soil Using NPK and Moisture Sensors
Authors: Shravani  , Shetty Diya Nithyananda  , Raghavendra M O  , Ramu Shivappa Hirur  , Tenson Jose
Published: December 2024

With an emphasis on the combination of NPK (nitrogen, phosphorus, and potassium) and moisture sensors, this review paper explores the critical role that contemporary sensor technology plays in identifying soil nutrients and moisture levels. Precision agriculture, which seeks to optimize irrigation and fertilization techniques based on real-time data, depends on accurate measurement of these parameters. The study looks at different kinds of moisture and NPK sensors, describing how they operate and how they are used in agricultural settings. There are various advantages to incorporating these sensors into farming operations. One of the biggest benefits is increased agricultural yields since optimal plant growth is ensured by accurate fertilizer and moisture management. Another important advantage is cost effectiveness; farmers can save input costs and boost profitability by eliminating excessive fertilization and irrigation. Additionally, efficient resource usage promotes sustainable farming methods, which improve soil health and lessen environmental deterioration. The content of vital nutrients in the soil can be determined using NPK sensors. These sensors allow farmers to customize their fertilization plans to match the unique requirements of their crops by giving them real-time information on the levels of nitrogen, phosphorus, and potassium. This accuracy guarantees that plants get the appropriate quantity of nutrients at the right time, leading to improved crop yields and reduced environmental impact. This paper identifies the need for developing superior systems for soil monitoring to strengthen precision agriculture, crop production, and sustainable farming.
La circulation des livres dans l’espace post-yougoslave : territoires, politiques du livre et stratégies éditoriales
Authors: Madelain Anne
Published: December 2024

Après l’éclatement violent de la Fédération yougoslave en 1991 et la fin du régime socialiste, le monde professionnel du livre s’est réorganisé à l’intérieur des nouvelles frontières étatiques et nationales, tant dans la zone linguistique de l’ex-serbo-croate que dans les territoires où dominent le slovène, le macédonien et l’albanais. Les grandes entreprises publiques combinant activités d’édition, d’impression et de distribution ont laissé la place à une multitude d’acteurs privés plus ou moins pérennes. Les États successeurs de la Yougoslavie ont tenté de redéfinir les circuits de distribution du livre autant que les formes de légitimité à l’intérieur des nouvelles frontières. Pourtant, l’étroitesse des marchés, la proximité linguistique et culturelle ainsi que les nouvelles coopérations post-yougoslaves ont incité, dès le début des années 2000, éditeurs, auteurs ou distributeurs à élargir leurs territoires de diffusion malgré des difficultés matérielles et politiques. Par ailleurs, l’information bibliographique est un domaine où la coopération s’est révélée nécessaire, autant pour gérer les fonds patrimoniaux que pour documenter les parutions récentes. Cet article se penche sur plusieurs exemples de tensions entre l’affirmation d’un territoire national – et souvent linguistique – de production/diffusion du livre et des phénomènes qui lui échappent ou la contredisent.
« Élever des citoyens d’un monde sans frontières ». L’évolution de l’édition jeunesse indépendante russe, 2003-2024
Authors: Delacroix Ostromooukhova Bella
Published: December 2024

Cet article est centré sur un petit ensemble de maisons d’édition jeunesse russes, apparues entre 2003 et 2013, qui se réclament d’une position critique vis-à-vis de la « production de masse » commerciale des grandes maisons d’édition nationales. Leur portefeuille éditorial, ancré dans le marché mondial de littérature jeunesse, vise à promouvoir une littérature véhiculant des « valeurs humanistes » afin de populariser l’idée de « citoyen d’un monde sans frontières ». L’article analyse les stratégies de légitimation utilisées par les fondateurs et fondatrices de ces maisons d’édition afin d’affirmer leur autonomie par rapport aux grandes entreprises et à l’État ; les oscillements de cet ensemble entre le pôle de l’édition restreinte et celui de la production commerciale ; la façon dont elles construisent et négocient leur présence tant sur le territoire national que sur le marché « occidental ». Fragilisées et menacées de répressions par le durcissement autoritaire du régime politique russe, les maisons d’édition étudiées jouent sur l’équilibre subtil entre confidentialité et renommée, en créant et en élargissant sans cesse des communautés de pensée qui incluent professionnels du livre et lectorat.
Circulation of the French language literature and the Croatian publishers in transition and post-transition periods
Authors: Mikšić Vanda , Sindičić-Sabljo Mirna
Published: December 2024

Cet article est basé sur une recherche dont l’objectif est de déterminer les modalités de circulation de la littérature de langue française traduite en croate à partir de 1991. Nous nous intéressons principalement à la place de la littérature de langue française dans les catalogues des maisons d’édition croates, aux critères de sélection des titres à traduire, aux subventions disponibles, à la coopération avec les différents acteurs du champ littéraire et aux stratégies marketing utilisées pour promouvoir les livres traduits. Après une présentation de l’industrie de l’édition croate et des traductions littéraires du français entre 1991 et 2020, nous traitons et analysons les données recueillies par le biais d’une enquête adressée aux éditeurs croates via la plateforme en ligne LimeSurvey. Ensuite, nous présentons nos conclusions concernant la circulation des textes littéraires français dans la culture croate à partir de 1991, la position de la littérature traduite dans la culture et la société croates, les conditions sociales de la production littéraire, la logique du marché, la structure du champ littéraire et la circulation transnationale des textes littéraires.
Anxiety and depression in primary knee osteoarthritis patients: are they related to clinical features and radiographic changes?
Authors: Abd Elhamid Yasmin A. , Elazkalany Ghada S. , Niazy Marwa H. , Afifi Angie Y.
Published: December 2024

Introduction

Osteoarthritis (OA) is a worldwide, disabling condition, more prevalent in older people. Although anxiety and depression disorders are common in OA and may affect compliance with treatment, both disorders are still underrecognized and undertreated. The present study aimed to screen for anxiety and depression among patients with primary knee OA, and to study the relationship between Hospital Anxiety and Depression Scale (HADS) score and different disease parameters.

Material and methods

Fifty patients fulfilling primary knee OA classification criteria were recruited for the study, and 50 age- and sex-matched healthy individuals served as a control group. Medical history was taken, clinical examination was done, and pain intensity was assessed using the Visual Analogue Scale. The 6-minute walk test was used for functional status assessment, and plain X-ray knees were scored according to the Kellgren and Lawrence classification system. Participants completed the HADS questionnaire.

Results

Twenty-nine patients were female (58%) and 21 were male (42%). The mean HADS score was significantly higher in OA patients than controls (p = 0.001). The mean HADS-A (Anxiety) score was statistically significantly higher in OA patients than controls (p < 0.001). Anxiety was more frequent in patients (44%) than in controls (10%) (p < 0.001). In regression analysis, female sex could be considered as a predictor for each of HADS-A and HADS-D (Depression) (b: 0.4, 0.3; t: 3.28, 2.2; p = 0.002, 0.03; CI: 1.3–5.6, 0.2–4.4), respectively, while knee giving way was considered as a predictor for HADS-A (b: 0.34, t: 2.8, p = 0.007, CI: 0.96–5.87).

Conclusions

The results of the present study showed that anxiety level rather than depression was significantly higher in patients with primary knee OA than in controls. Female sex could be considered as a predictor for each of HADS-A and HADS-D, while knee giving way was considered as a predictor for HADS-A.
Key personal insights and changing needs of osteoarthritis patients: an international quantitative survey analysis
Authors: Szekanecz Zoltan , Osadcii-Zaiat Diana , Bajkó András , Minda Hajnalka , Szerencsés Dóra
Published: December 2024

Introduction

Osteoarthritis (OA) presents significant challenges, imposing limitations on patients’ daily activities. Factors such as restricted mobility, sedentary lifestyles, social isolation, and weight gain can exacerbate the difficulties faced by these individuals. Our study aimed to identify the needs and personal challenges faced by individuals with OA, and the impact of the COVID-19 pandemic.

Material and methods

The research included a quantitative survey and a workshop involving a Scientific Leader Team. The quantitative survey was conducted among 400 patients in Bulgaria, Romania, Serbia, and Kazakhstan. All enrolled participants had experienced chronic musculoskeletal pain due to OA for at least three years and had received treatment with topical or oral medications. The cross-country workshop, conducted via Zoom, brought together prominent rheumatologists to discuss the survey results and explore patient support opportunities with healthcare providers.

Results

Over 60% of respondents reported that poor locomotor function adversely affected their daily activities. More than 50% stated that they had delayed treatment due to concerns about potential side effects, while over half expressed a desire for rapid pain relief. Approximately 30% of patients reported an increase in musculoskeletal complaints following the onset of the COVID-19 pandemic. The proportion of online consultations rose significantly, increasing from 5% before the pandemic to 12% during it, before stabilizing at 9% in the post-pandemic period.

Conclusions

Patients with OA face considerable limitations in their daily lives, with a strong prefe­rence for immediate pain relief. Concerns about side effects lead many to postpone treatment. Over-the-counter anti-inflammatory creams and prescription oral anti-inflammatory drugs are the most used therapies. The pandemic negatively affected OA symptoms. Furthermore, the use of online channels for OA patient care increased during the COVID-19 pandemic.
Immunobiologics in juvenile dermatomyositis: a systematic review of promising therapeutic advances
Authors: Rocha Aline Maria de Oliveira , Ribeiro Gabriel Fidelis , Silva Juliana Capecce
Published: December 2024

Introduction

To identify the most effective treatment for juvenile dermatomyositis (JDM), considering efficacy, safety, impact on patients and improvement in their quality of life.

Material and Methods

A systematic review was carried out comparing known treatments and immunobiological therapies, evaluating clinical improvement, adverse events and prognosis. The MEDLINE, PubMed, LILACS and Cochrane Library databases were used with children aged 0 to 18 diagnosed with JDM. The PRISMA 2020 statement was followed throughout the process.

Results

The immunobiologics studied were rituximab (RTX) and anti-tumor necrosis factor drugs and used the Disease Activity Score to skin, Childhood Myositis Assessment Scale and Manual Muscle Testing tools. There was no difference in the response when RTX was used (early or late). The anti-TNF studies were carried out in a population that was refractory to the initial treatment and showed a significant improvement in muscle and skin disease activity.

Conclusions

For severe or refractory disease, biologics tend to be the medication with the best therapeutic response.
Nanomaterials in Medicine: Advancing Drug Delivery, Diagnostics, and Therapeutics
Authors: Kader Nasreen
Published: December 2024

Nanomaterials have revolutionized various fields of medicine, providing innovative solutions for drug delivery, diagnostics, vaccines, and regenerative therapies. The aim of this review is to explore the diverse applications of nanomaterials in medicine, highlighting their potential to enhance treatment efficacy, improve patient outcomes, and address complex medical challenges. Through successful applications like Doxil and Abraxane, nanotechnology has demonstrated its ability to improve targeted drug delivery, while lipid nanoparticles have played a pivotal role in the development of mRNA vaccines for COVID-19. Nanomaterials offer unique advantages, such as their small size, tunable surface properties, and the ability to cross biological barriers, which enable precision therapies and improved diagnostic sensitivity. However, this review also addresses the challenges associated with nanomaterials, including safety concerns, potential toxicity, long-term biodegradability, and the regulatory hurdles that must be overcome for clinical translation. As researchers work to develop biocompatible and biodegradable materials, new opportunities arise in personalized medicine, stimuli-responsive nanomaterials, and theranostics that combine diagnosis and therapy into a single platform. In conclusion, while nanotechnology in medicine offers immense potential for future medical innovations, addressing safety and regulatory challenges will be crucial for the broader adoption of nanomaterials in clinical practice. This review emphasizes the need for continued research and development to realize the full potential of nanomedicine in improving healthcare outcomes globally.
ABORDAGEM FAMILIAR NA ATENÇÃO PRIMÁRIA: ESTUDO DE CASO DE UMA FAMÍLIA NO MUNICÍPIO DE TAIOBEIRAS, MINAS GERAIS, BRASIL
Authors: Silva Igor Matheus de Novais , Santos Larissa Alves , Soares Aruanda Kalinca Teixeira
Published: December 2024

Objetivo: Este estudo tem como objetivo descrever a utilização das ferramentas de abordagem familiar como parte do processo diagnóstico situacional de uma família de um município do norte de Minas Gerais. Método: Utilizou-se as ferramentas Genograma, Ecomapa, Ciclo de vida familiar, F.I.R.O., P.R.A.C.T.I.C.E., Plano Terapêutico Singular e Conferência familiar em 10 atendimentos domiciliares, tendo a paciente índice o diagnóstico de Esquizofrenia simples (CID 10 - F20.6). Resultados: Foram articuladas intervenções multidisciplinares de profissionais da Unidade Básica de Saúde, do NASF-AB e do Serviço Social do município, nas áreas de Enfermagem, Farmácia, Odontologia, Medicina, Psicologia, Assistência Social, Fisioterapia e Nutrição. O uso das ferramentas e o olhar crítico multidisciplinar possibilitou a execução de ações que perpassam a assistência curativa, favorecendo o entendimento das individualidades de cada membro familiar, os papéis de cada um e a forma como enfrentam seus conflitos. Conclusão: Evidenciou-se a abordagem familiar como um meio de interação e compreensão das relações entre os indivíduos, além de permitir o estabelecimento de vínculo e o entendimento do processo saúde-doença.
SENI TULIS ARAB DI NUSANTARA: PERKEMBANGAN KALIGRAFI ISLAM DI INDONESIA PASCA KEMERDEKAAN (1945–1985)
Authors: Ridwanuloh Luki , Umam Muhammad Mufti Najmul , Mulyana Agus
Published: December 2024

Penelitian ini menjelaskan tentang sejarah serta perkembangan seni kaligrafi Islam, serta perkembangannya di Indonesia pasca kemerdekaan hingga tahun 1985. Bagaimana sejarah Kaligrafi? Bagaimana sejarah kaligrafi pada masa pra kemerdekaan? Bagaimana perkembangan kaligrafi pada tahun 1945-1985 perkembangan kebudayaan Islam berupa seni Islam yaitu kaligrafi. Penelitian ini akan menjelaskan perkembangan kaligrafi pasca kemerdekaan yang mengambil kasus Quran Pusaka, perlombaan kaligrafi pada ajang MTQ, serta lahirnya lembaga kaligrafi pertama di Indonesia, Metodologi yang digunakan dalam penulisan penelitian ini adalah metodologi penelitian historis dan dalam penelitian ini, peneliti fokus pada sumber pustaka atau library research, yaitu penelitian yang mengungkap fakta lewat data pustaka. Adapun penelitian mengambil dua teori yang digunakan diantaranya, Teori Challenge and Response dari Arnold. J. Toynbee, Dan Teori Fungsionalism dari Bronislaw K. Malinowski. Hasil penelusuran dari berbagai kajian ilmiah mengungkapkan bahawa penulis Quran Pusaka Republik Indonesia adalah Prof. H.M Salim Fachry yang merupakan seorang kaligrafer, Quran Pusaka Republik Indonesia sendiri menjadi awal perkembangan kaligrafi di Indonesia pasca kemerdekaan. Dan yang mendirikan lembaga kaligrafi pertama di Indonesia adalah Drs. Didin Sirojuddin A.R. dengan nama Lembaga Kaligrafi Al-Quran (LEMKA)
KONTRIBUSI KERAJAAN MUGHAL TERHADAP PERKEMBANGAN ISLAM DI ANAK BENUA INDIA
Authors: Nurcahya Yan , Hambaliana Dandie , Solehudin Solehudin
Published: December 2024

Consist The Mughal Empire, also known as the Moguls or Moghuls, was a state that ruled Afghanistan, Balochistan, and most of India between 1526 AD and 1857 AD. Mughal is the Indo-Aryan version of the word Mongol, as it was part of the Timurid dynasty from Central Asia. Officially the Mughal people were Muslims. In this period three great kings were formed: the Ottomans in Türkiye, the Shafavids in Persia, and the Mughals in India. The Mughals controlled the entire region, causing significant changes in the Islamic world. Babur was the first to establish an Islamic kingdom in India, and his son, Nashiruddin Humayun (1530-1539 AD), succeeded him. Muslims in India are considered a minority, and their influence is felt across various religions. Muslims were considered a minority within Islam, and their influence was further spread by Mughal rule. It was during this period that Islam spread and developed in the Indian Subcontinent. In terms of methodology, historical research is the study of various historical sources, both primary and secondary. From the paper presented, we can see the contribution of the Mughal Empire to the development of Islam in the Indian Subcontinent in various aspects at that time, including; Politics, Education, Science, Literature, Architecture, Technology and City Development.
Gerakan Filantropi Pendidikan Dompet Dhuafa Tahun 1999-2011
Authors: Basthomi Imam
Published: December 2024

Salah satu topik yang menarik untuk dibahas di Indonesia adalah mengenai Filantropi Islam. Indonesia sebagai negara dengan jumlah penduduk muslim yang besar memiliki banyak lembaga filantropi Islam. Lembaga filantropi Islam memiliki peran dalam mensejahterakan umat, termasuk dalam bidang pendidikan. Kualitas pendidikan tidak dapat dicapai oleh satu pihak saja, tetapi harus ada beberapa pihak yang bekerja sama. Penelitian ini mengeksplorasi bagaimana Dompet Dhuafa sebagai salah satu lembaga filantropi Islam di Indonesia dapat berkontribusi dalam bidang pendidikan. Penelitian ini dilakukan dengan menggunakan pendekatan kualitatif dengan penjelasan deskriptif. Metode pengumpulan data dan cara menganalisis menggunakan metode sejarah (heuristik, kritik, interpretasi, historiografi). Penelitian ini menemukan bahwa Dompet Dhuafa memiliki peran vital dalam bidang pendidikan. Dompet Dhuafa dalam bidang pendidikan, memberdayakan dana filantropi untuk pemberian beasiswa dan pendirian lembaga pendidikan serta pengembangan mutu pendidikan.
Поиск новых катаклизмических переменных в различных рентгеновских и оптических каталогах
Authors: Галиуллин И.И.
Published: December 2024

Катаклизмические переменные (КП) — это двойные системы, в которых белый карлик аккрецирует вещество со звезды-компаньона, заполняющей свою полость Роша. Многочисленные КП проявляют себя на оптических кривых блеска как переменные источники. Более того, аккреция может приводить к вспышкам, которые видны в оптических кривых блеска, особенно у немагнитных КП. Я рассматриваю современный многоволновой подход к классификации новых КП среди звездных объектов, основанный на “рентгеновской главной последовательности”, фазовом простран- стве отношения рентгеновского и оптического потоков и оптическом цвете Gaia (BP–RP). Используя этот метод, мож- но выявить множество новых кандидатов в КП при перекрестном сопоставлении различных рентгеновских каталогов, данных о собственном движении Gaia и базы данных оптических переменных объектов Zwicky Transient Facility. В работе я рассуждаю о недавно открытых новых магнитных и немагнитных КП, включая затменно-переменные ис- точники типа AM CVn и period bouncer. Эти результаты показывают, что многоволновой подход может быть мощным инструментом для поиска аккрецирующих двойных систем в рентгеновских и оптических каталогах.

Cataclysmic variables (CVs) are binary systems in which a white dwarf accretes matter from a Roche-lobe-filling companion star. Numerous CVs can be seen in optical light curves as periodic sources. Moreover, accretion can result in outbursts, which are visible in their optical light curves, especially in non-magnetic CVs. I review a modern multiwavelength approach to classifying new CVs among stellar objects based on an X-ray main sequence, a phase space of X-ray-to-optical flux ratio, and a Gaia optical (BP–RP) color. Using this method, it is possible to identify a dozen new CV candidates in a cross-match of different X-ray catalogs, Gaia proper motion data, and the optical Zwicky Transient Facility database. I discuss the recently discovered new magnetic and non-magnetic CVs, including an eclipsing AM CVn and the period-bouncer CV. These results show that a multiwavelength approach can be a powerful tool for searching for accreting binary systems in X-ray and optical catalogs.
Students’ preference for dentistry: effective factors and personality analysis
Authors: Temur Katibe Tuğçe , Katırcıoğlu Alper
Published: December 2024

Aims: The aim of this study was to understand the personality traits and occupational preferences of dental students and to
evaluate the possible relationships between these two factors.
Methods: In this study, research was conducted on volunteer students studying at Niğde Ömer Halisdemir University Faculty
of Dentistry in the 2023-2024 academic year. The research questions and the Eysenck Personality Questionnaire Revised/
Shortened Form (EKA-GGK) were administered to the participants through face-to-face interviews. Sociodemographic
characteristics, reasons for choosing a profession and personality traits of the students were evaluated.
Results: 20.32% of the participants preferred dentistry because it is ta prestigious profession in the society, followed by
financial return (18.32%) and job guarantee (14.97%). There was no significant relationship between the results of the Eysenck Personality Scale and the reasons for choosing dentistry as a profession (p>0.05). In the study, the neuroticism sub-dimension was found to be significantly higher in female participants than in male participants (p=0.017). Extraversion, psychoticism nd lying sub-dimensions did not show a significant difference according to variables such as gender, age, number of siblings, mother’s education level and income level. However, it was observed that the level of father’s education was effective on the extraversion score; children of fathers who graduated from high school had higher extraversion scores compared to children of fathers with secondary school or lower education level (p=0.045).
Conclusion: Social status and financial return were the most important reasons for students to choose dentistry, while family
desire was less effective. The results of the Eysenck Personality Scale showed that the students were generally emotionally
balanced, open to social relationships, compliant with social norms and non-aggressive individuals.
Office type vital teeth bleaching: presentation of four cases
Authors: Salık Mehmet , Bakır Elif Pınar , Bakır Şeyhmus
Published: December 2024

The tooth color, which is primarily determined by the dentin tissue, is also influenced by the color, transparency, and thickness of the enamel. Color changes in teeth that occur over time due to intrinsic or extrinsic factors are a significant aesthetic issue that requires treatment. Discoloration, especially in the front teeth, leads to a loss of self-confidence in patients, and as a result, they are unable to smile comfortably. It is usually possible to remove extrinsic stains, which are associated with poor oral hygiene and the consumption of certain foods and beverages throughout the day, using mechanical cleaning methods. In the removal of intrinsic stains, vital whitening (bleaching) is preferred over more invasive treatment methods. Vital tooth whitening, which is considered a minimally invasive approach, includes procedures performed by the dentist in the office (in-office) or at home by the patient under the dentist's guidance. In both applications, the active ingredient in the materials used is hydrogen peroxide( H²O²) or carbamide peroxide. These agents can be used alone or in combination with activation methods such as heat or light. The aim of this study is to demonstrate the effectiveness of in-office whitening treatments in various discoloration cases.
Judicial Jurisdiction of the Iraqi State Council: A Comparative Study withThe Saudi Board of Grievances
Authors: Fayadh Ali Mukhlif Hammad
Published: December 2024

Judicial oversight is one of the most important safeguards to ensure the principle of legality, which requires that the administration respect the law in its actions and decisions. Respect for the law by the administration can only be achieved through judicial oversight of its activities. This oversight is one of the strongest contemporary guarantees to uphold the principle of legality. States regulate judicial oversight of administrative actions in two main ways: the first involves establishing a single judicial entity responsible for resolving all disputes, including administrative disputes (known as the unified judiciary system), while the second approach establishes two separate judicial bodies, one responsible for resolving administrative disputes and the other for civil disputes among individuals subject to private law (known as the dual judiciary system).Iraq adopted the dual judiciary system when the Administrative Judiciary Court was established in 1989. On the other hand, in the Kingdom of Saudi Arabia, the creation of the Administrative Judiciary was linked to the establishment of the Board of Grievances in 1373 AH (1953 AD).
The Fundamental Principlesof Predestination and Obligation After Choice in The Hanafi School: A Jurisprudential Study
Authors: Al-Samarrai Omar Taha Khalil
Published: December 2024

The aim of the research is to elucidate the foundational principles of necessity and obligation, which have been distinguished by several key philosophical concepts formulated by the Hanafi school through the issues used to understand necessity and obligation after choice. It highlights the content of the principles of necessity and obligation, and the obligation principle, which indicates that individuals are obliged to act based on ethical values and principles, subject to surrounding conditions and circumstances. The importance of the study lies in shedding light on the concept of necessity and obligation after choice, as it holds significant importance in the Hanafi school, which is one of the major schools of Islamic jurisprudence. The Hanafi school focuses greatly on understanding the legal, ethical, and moral consequences of human choices and actions. The study primarily followed a descriptive-analytical-inductive methodology, integrating it with a historical methodology that includes studying the historical context of the foundational principles in the Hanafi school, and a comparative methodology, comparing individual narratives in Hanafi traditions and foundational principles with similar principles in other groups. The study concluded with several findings, the most prominent of which is that the principle of foundational rules of necessity and obligation after choice is considered an important principle in the Hanafi school and in Islamic jurisprudence in general.