bluuebunny/crossref_metadata_2025 huggingface dataset:
Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766)
Authors: Wigmore E M , Clarke T-K , Howard D M , Adams M J , Hall L S , Zeng Y , Gibson J , Davies G , Fernandez-Pujals A M , Thomson P A , Hayward C , Smith B H , Hocking L J , Padmanabhan S , Deary I J , Porteous D J , Nicodemus K K , McIntosh A M
Published: August 2017

Major depressive disorder (MDD) is a heritable and highly debilitating condition. It is commonly associated with subcortical volumetric abnormalities, the most replicated of these being reduced hippocampal volume. Using the most recent published data from Enhancing Neuroimaging Genetics through Meta-analysis (ENIGMA) consortium’s genome-wide association study of regional brain volume, we sought to test whether there is shared genetic architecture between seven subcortical brain volumes and intracranial volume (ICV) and MDD. We explored this using linkage disequilibrium score regression, polygenic risk scoring (PRS) techniques, Mendelian randomisation (MR) analysis and BUHMBOX. Utilising summary statistics from ENIGMA and Psychiatric Genomics Consortium, we demonstrated that hippocampal volume was positively genetically correlated with MDD (rG=0.46, P=0.02), although this did not survive multiple comparison testing. None of the other six brain regions studied were genetically correlated and amygdala volume heritability was too low for analysis. Using PRS analysis, no regional volumetric PRS demonstrated a significant association with MDD or recurrent MDD. MR analysis in hippocampal volume and MDD identified no causal association, however, BUHMBOX analysis identified genetic subgrouping in GS:SFHS MDD cases only (P=0.00281). In this study, we provide some evidence that hippocampal volume and MDD may share genetic architecture in a subgroup of individuals, albeit the genetic correlation did not survive multiple testing correction and genetic subgroup heterogeneity was not replicated. In contrast, we found no evidence to support a shared genetic architecture between MDD and other regional subcortical volumes or ICV.
Investigation of mass transfer limitations in simultaneous esterification and transesterification of triglycerides using a heterogeneous catalyst
Authors: Bhoi Rohidas , Singh Dheerendra , Mahajani Sanjay
Published: August 2017

Schematic representation of the concentration profile of methanol across all the interfaces in a FBR.
Microchip electrophoresis utilizing an in situ photopolymerized Phos-tag binding polyacrylamide gel for specific entrapment and analysis of phosphorylated compounds
Authors: Yamamoto Sachio , Himeno Miyuki , Kobayashi Masaya , Akamatsu Miki , Satoh Ryosuke , Kinoshita Mitsuhiro , Sugiura Reiko , Suzuki Shigeo
Published: August 2017

A method was developed for the specific entrapment and separation of phosphorylated compounds using a Phos-tag polyacrylamide gel fabricated at the channel crossing point of a microfluidic electrophoresis chip.
Hyperspectral depth-profiling with deep Raman spectroscopy for detecting chemicals in building materials
Authors: Cho Youngho , Song Si Won , Sung Jiha , Jeong Young-Su , Park Chan Ryang , Kim Hyung Min
Published: August 2017

Hyperspectral Raman spectroscopy was combined with reference subtraction method to measure toxic chemicals inside building materials and their spatial distribution.
A single-round selection of selective DNA aptamers for mammalian cells by polymer-enhanced capillary transient isotachophoresis
Authors: Hirose Kazuki , Tsuchida Maho , Asakura Hinako , Wakui Koji , Yoshimoto Keitaro , Iida Keisuke , Sato Makoto , Shibukawa Masami , Suganuma Masami , Saito Shingo
Published: August 2017

A single-round DNA aptamer selection for mammalian cells was successfully achieved for the first time using a capillary electrophoresis (CE)-based methodology.
Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets
Authors: Huang Guangzao , Yuan Mingshun , Chen Moliang , Li Lei , You Wenjie , Li Hanjie , Cai James J. , Ji Guoli
Published: August 2017

The application of machine learning in cancer diagnostics has shown great promise and is of importance in clinic settings.
Defined tetranuclear coinage metal chains
Authors: Kaub Christoph , Lebedkin Sergei , Bestgen Sebastian , Köppe Ralf , Kappes Manfred M. , Roesky Peter W.
Published: August 2017

Heterodimetallic gold/copper and gold/silver complexes were synthesized, and feature an unprecedented V-shape or linear MAu2M (M = Cu, Ag) setup in the solid state. Photoluminescence properties of the complexes strongly depend on the metal.
pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates
Authors: Ji Xingyue , De La Cruz Ladie Kimberly C. , Pan Zhixiang , Chittavong Vayou , Wang Binghe
Published: August 2017

Carbon monoxide prodrugs with triggered release profiles are highly desirable for targeted CO delivery to minimize their untoward side-effects.
A highly efficient 2D exfoliated metal dichalcogenide for the on-farm rapid monitoring of non-esterified fatty acids
Authors: Tuteja Satish K. , Neethirajan Suresh
Published: August 2017

Liquid phase exfoliation of 2D MoS2and bioconjugation with NEFA antibodies to develop a biointerface over the SPE.
From aqueous speciation to supramolecular assembly in alkaline earth-uranyl polyoxometalates
Authors: Falaise Clément , Hickam Sarah M. , Burns Peter C. , Nyman May
Published: August 2017

Macrocation and macroanion Sr-uranyl hybrid capsules self-assemble into an ionic lattice, presenting the fourth largest inorganic unit cell reported.
Activation of C–H bonds by rare-earth metallocene-butyl complexes
Authors: Grindell Richard , Day Benjamin M. , Guo Fu-Sheng , Pugh Thomas , Layfield Richard A.
Published: August 2017

The stable metallocene-butyl complexes [(CpMe)2M(nBu)]2(M = Y, Dy) were synthesized and their reactivity towards to ferrocene and bulky N-heterocyclic carbenes investigated.
Characterization of the HCN⋯CO complex and its radiation-induced transformation to HNC⋯CO in cold media: an experimental and theoretical investigation
Authors: Kameneva Svetlana V. , Tyurin Daniil A. , Feldman Vladimir I.
Published: August 2017

Radiation-induced transformations of the astrochemically important HCN⋯CO complex in cold media result in highly efficient isomerization to the HNC⋯CO complex.
Enhancing thermoelectrochemical properties by tethering ferrocene to the anion or cation of ionic liquids: altered thermodynamics and solubility
Authors: Aldous Leigh , Black Jeffrey J. , Elias Maximo C. , Gélinas Bruno , Rochefort Dominic
Published: August 2017

The thermoelectrochemistry of ferrocene tethered to anions and cations expands current theory to entropy changes involving zwitterions and adjacent charges.
Modulation of ICT probability in bi(polyarene)-based O-BODIPYs: towards the development of low-cost bright arene-BODIPY dyads
Authors: Gartzia-Rivero Leire , Sánchez-Carnerero Esther M. , Jiménez Josue , Bañuelos Jorge , Moreno Florencio , Maroto Beatriz L. , López-Arbeloa Iñigo , de la Moya Santiago
Published: August 2017

Bi(polyarene)-based O-BODIPYs, a valuable and tunable scaffold for photonics.
Solar-driven simultaneous steam production and electricity generation from salinity
Authors: Yang Peihua , Liu Kang , Chen Qian , Li Jia , Duan Jiangjiang , Xue Guobin , Xu Zisheng , Xie Wenke , Zhou Jun
Published: August 2017

A hybrid energy utilization technology using solar energy for desalination and extracting electricity from an evaporation induced salinity gradient is presented.
Chemisorption of CO2by chitosan oligosaccharide/DMSO: organic carbamato–carbonato bond formation
Authors: Qaroush Abdussalam K. , Assaf Khaleel I. , Bardaweel Sanaa K. , Al-Khateeb Ala'a , Alsoubani Fatima , Al-Ramahi Esraa , Masri Mahmoud , Brück Thomas , Troll Carsten , Rieger Bernhard , Eftaiha Ala'a F.
Published: August 2017

A novel oligochitosan/DMSO system as a green sorbent for CO2capturing.
Quantitative profiling of innate immune activation by viral infection in single cells
Authors: Timm Andrea C. , Warrick Jay W. , Yin John
Published: August 2017

We have identified critical aspects of the competition between a virus and its host's immune-response, within single-cells using fluorescent reporters.
Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
Authors: Cornaglia Matteo , Lehnert Thomas , Gijs Martin A. M.
Published: August 2017

A review of the latest research on microfluidic devices forC. elegansanalysis reveals a clear potential for their fruitful application in high-throughput and high-content screening contexts.
mRNA–miRNA bipartite network reconstruction to predict prognostic module biomarkers in colorectal cancer stage differentiation
Authors: Motieghader Habib , Kouhsar Morteza , Najafi Ali , Sadeghi Balal , Masoudi-Nejad Ali
Published: August 2017

Biomarker detection is one of the most important and challenging problems in cancer studies.
An in-depth study into the growth aspects and characteristic properties of ethyl 4-amino benzoate: a potential candidate for electro-optical applications
Authors: Krishna Anuj , Vijayan N. , Sonia Sonia , Vij Mahak , Sridhar B. , Soumya H. , Singh Budhendra , Das Subhasis , Maurya K. K.
Published: August 2017

We present the bulk growth and characterization of an EPAB crystal using a single zone transparent resistive furnace.
Synthesis and analysis of the anticancer activity of Ru(ii) complexes incorporating 2-hydroxymethylidene-indene-1,3-dione ligands
Authors: Tsovaltzi E. , Malamidou-Xenikaki E. , Dalezis P. , Hatzidimitriou A. , Lazarides T. , Trafalis D. , Sarli V.
Published: August 2017

Piano-stool Ru(ii) complexes incorporating 2-hydroxymethylidene-indene-1,3-dione ligands exhibit promising anticancer activity against four human ovarian cancer cell lines.
Covalent modification of biological targets with natural products through Paal–Knorr pyrrole formation
Authors: Kornienko Alexander , La Clair James J.
Published: August 2017

This review examines the extent to which natural systems have adopted the Paal–Knorr reaction to engage nucleophilic amine groups within biological targets.
Small molecule-driven directional movement enabling pin-hole free perovskite film via fast solution engineering
Authors: Gao Li-Li , Zhang Ke-Jie , Chen Lin , Chen Ni , Li Cheng-Xin , Li Chang-Jiu , Yang Guan-Jun
Published: August 2017

Small molecules (helium) driven directional diffusion movement precipitates pin-hole free perovskite films and high efficiency solar cells.
Anion photoelectron spectroscopy of free [Au25(SC12H25)18]−
Authors: Hirata Keisuke , Yamashita Keishiro , Muramatsu Satoru , Takano Shinjiro , Ohshimo Keijiro , Azuma Toshiyuki , Nakanishi Ryuzo , Nagata Takashi , Yamazoe Seiji , Koyasu Kiichirou , Tsukuda Tatsuya
Published: August 2017

The adiabatic electron affinity of [Au25(SC12H25)18]0 was experimentally determined to be 2.2 eV by anion photoelectron spectroscopy.
Laser flash photolysis of nanocrystalline α-azido-p-methoxy-acetophenone
Authors: Sarkar Sujan K. , Gatlin DeVonna M. , Das Anushree , Loftin Breyinn , Krause Jeanette A. , Abe Manabu , Gudmundsdottir Anna D.
Published: August 2017

Irradiation of nanocrystals of azide1results in a solid-to-solid photoreaction that forms imine2in high chemical yield.
An enzymatic strategy to asymmetrically branched N-glycans
Authors: Calderon Angie D. , Zhou Jun , Guan Wanyi , Wu Zhigang , Guo Yuxi , Bai Jing , Li Qing , Wang Peng George , Fang Junqiang , Li Lei
Published: August 2017

Using a set of glycosidases and glycosyltransferases, an enzymatic strategy was developed to prepare asymmetricN-glycans excluding any chemical procedures.
A photoactivatable photochromic system serves as a self-hidden information storage material
Authors: Li Yuanyuan , Li Kai , Tang Ben Zhong
Published: August 2017

A photoactivatable self-hidden information storage material was designed and facilely synthesized, which makes the recorded information safe and covert.
Synthesis and immunochemical evaluation of a novel Neisseria meningitidis serogroup A tetrasaccharide and its conjugate
Authors: Harale Kishore R. , Rout Jeetendra K. , Chhikara Manoj Kumar , Gill Davinder S. , Misra Anup Kumar
Published: August 2017

A tetrameric repeating unit of capsular polysaccharide of Neisseria meningitidis serogroup A was synthesized which mimicked natural polysaccharide in immunochemical analysis.
Green synthesis of silver nanoparticles using seed extract of Alpinia katsumadai, and their antioxidant, cytotoxicity, and antibacterial activities
Authors: He Yangqing , Wei Fenfei , Ma Zhanying , Zhang Hao , Yang Qian , Yao Binghua , Huang Zhengrui , Li Jie , Zeng Cun , Zhang Qian
Published: August 2017

A rapid green approach for synthesizing of silver nanoparticles using Alpinia katsumadai seed extract is described and their antioxidant, antibacterial and cytotoxicity activities evaluated.
Influence of melt-draw ratio on the crystalline behaviour of a polylactic acid cast film with a chi structure
Authors: Xu Ruijie , Xie Jiayi , Lei Caihong
Published: August 2017

Herein, polylactic acid cast films were prepared with different melt-draw ratios via an extrusion casting process. The oriented structure appeared at first and then a chi structure crystal was formed at higher MDR.
Scalable synthesis of carbon stabilized SiO/graphite sheets composite as anode for high-performance Li ion batteries
Authors: Zhang Qianliang , Lin Ning , Xu Tianjun , Shen Kangze , Li Tieqiang , Han Ying , Zhou Jie , Qian Yitai
Published: August 2017

Various carbon coated SiO/graphite composites are fabricated through in situ polymerization and followed by annealing for high-performance Li-ion batteries.
The ethanol mediated-CeO2-supported low loading ruthenium catalysts for the catalytic wet air oxidation of butyric acid
Authors: Wang Yanmin , Yu Chaoying , Meng Xu , Zhao Peiqing , Chou Lingjun
Published: August 2017

The Ru/CeO2-A catalyst shows the higher activity for CWAO of butyric acid because of the adding of absolute ethanol.
Cs2CO3-promoted cross-dehydrogenative coupling of thiophenols with active methylene compounds
Authors: Chen Qian , Wang Xiaofeng , Wen Chunxiao , Huang Yulin , Yan Xinxing , Zeng Jiekun
Published: August 2017

α-Sulfenylation of carbonyl compounds has been achieved via Cs2CO3-promoted aerobic cross-dehydrogenative coupling of thiophenols with active methylene compounds.
Noncytotoxic polycaprolactone-polyethyleneglycol-ε-poly(l-lysine) triblock copolymer synthesized and self-assembled as an antibacterial drug carrier
Authors: Zhou Chuncai , Zhou Xinyu , Su Xiaokai
Published: August 2017

The PCL35-b-PEG45-b-EPL23 vesicles perform well in vitro drug release and antibacterial activity against Gram− and Gram+ bacteria with low cytotoxicity.
Dynamic/quasi-static stab-resistance and mechanical properties of soft body armour composites constructed from Kevlar fabrics and shear thickening fluids
Authors: Qin Jianbin , Zhang Guangcheng , Zhou Lisheng , Li Jiantong , Shi Xuetao
Published: August 2017

Soft body armour composites were constructed by combining Kevlar fabrics with different quantities of shear thickening fluid (STF).
Copper-catalyzed cyanothiolation to incorporate a sulfur-substituted quaternary carbon center
Authors: Huang Yubing , Li Xianwei , Wang Xu , Yu Yue , Zheng Jia , Wu Wanqing , Jiang Huanfeng
Published: August 2017

A copper-catalyzed cyanothiolation of N-tosylhydrazones with thiocyanates to generate α-arylthioalkanenitriles bearing sulfur-substituted quaternary carbon center atoms has been achieved.
The mechanism of transmethylation in anisole decomposition over Brønsted acid sites: density functional theory (DFT) study
Authors: Zhang Jiajun , Fidalgo Beatriz , Kolios Athanasios , Shen Dekui , Gu Sai
Published: August 2017

An acid catalyst promotes transmethylation in anisole decomposition through a dual electrophilic attack mechanism, lowering intrinsic energy barriers by up to 60 kcal mol−1.
A nitrogen rich polymer as an organo-catalyst for cycloaddition of CO2to epoxides and its application for the synthesis of polyurethane
Authors: Verma Shailesh , Kumar Gaurav , Ansari Amamudin , Kureshy Rukhsana I. , Khan Noor-ul H.
Published: August 2017

A nitrogen-rich cyanuric–urea polymer (CUP) was synthesized in a single step under solvent free conditions.
Organic–inorganic hybrid electrolytes from ionic liquid-functionalized octasilsesquioxane for lithium metal batteries
Authors: Yang Guang , Chanthad Chalathorn , Oh Hyukkeun , Ayhan Ismail Alperen , Wang Qing
Published: August 2017

Ionic liquid-based solid electrolytes with outstanding room-temperature ionic conductivity and excellent electrochemical stability are developed for all-solid-state Li metal batteries.
High-rate capability of Na2FePO4F nanoparticles by enhancing surface carbon functionality for Na-ion batteries
Authors: Ko Jesse S. , Doan-Nguyen Vicky V. T. , Kim Hyung-Seok , Petrissans Xavier , DeBlock Ryan H. , Choi Christopher S. , Long Jeffrey W. , Dunn Bruce S.
Published: August 2017

Na-ion charge-storage kinetics of polyol-derived Na2FePO4F are enhanced by using a nanocomposite comprising nanoparticles and reduced graphene oxide.
Chemically fluorinated graphene oxide for room temperature ammonia detection at ppb levels
Authors: Kim Yeon Hoo , Park Ji Soo , Choi You-Rim , Park Seo Yun , Lee Seon Yong , Sohn Woonbae , Shim Young-Seok , Lee Jong-Heun , Park Chong Rae , Choi Yong Seok , Hong Byung Hee , Lee Jung Hun , Lee Wi Hyong , Lee Donghwa , Jang Ho Won
Published: August 2017

Detection of ppb level ammonia at room temperature is demonstrated using chemically fluorinated graphene oxide (CFGO). Fluorine adatom extremely enhances ammonia sensing capabilities through the changes of the charge distributions on adjacent functional groups, resulting in the variation in gas adsorption energies.
Rational design of multi-shelled CoO/Co9S8 hollow microspheres for high-performance hybrid supercapacitors
Authors: Wang Yaping , Zhu Ting , Zhang Yifang , Kong Xiangzhong , Liang Shuquan , Cao Guozhong , Pan Anqiang
Published: August 2017

Multi-shelled CoO/Co9S8 spheres were synthesized as hybrid supercapacitor materials due to the synergistic effect of CoO and Co9S8.
A two-photon-activated prodrug for therapy and drug release monitoring
Authors: Liu Peilian , Li Bowen , Zhan Chenyue , Zeng Fang , Wu Shuizhu
Published: August 2017

A two-photon-activated prodrug has been developed for drug release monitoring and photo-controllable therapy.
Metallic oxide nanocrystals with near-infrared plasmon resonance for efficient, stable and biocompatible photothermal cancer therapy
Authors: Dou Kang , Zhu Wenwen , Zou Yousheng , Gu Yu , Li Jubin , Zhang Shengli , Liu Zhuang , Zeng Haibo
Published: August 2017

The synthesized MoO2 nanocrystals exhibit excellent photothermal temperature elevation of about 37.5 °C under 808 nm laser irradiation, and tumor inhibition effects with an inhibition rate of up to 80.45% as a photothermal therapy agent against 4T1 cancer cells.
Even and odd oligothiophene-bridged bis-naphthalimides for n-type and ambipolar organic field effect transistors
Authors: Riaño Carnerero A. , López Espejo G. , Mancheño Real M. J. , Eckstein B. , González-Cano R. C. , Melkonyan F. S. , Facchetti A. , Marks T. J. , Casado J. , López Navarrete J. T. , Segura J. L. , Ponce Ortiz R.
Published: August 2017

Which effect directs supramolecular packing? π–π stabilizing interactions between two NDI units or dipole–dipole couplings?
AIE-active 9,10-bis(alkylarylvinyl)anthracences with pendent diethoxylphosphorylmethyl groups as solution-processable efficient EL luminophores
Authors: Sun Qikun , Qiu Xu , Lu Yuansheng , Xu Xin , Wang Honghong , Xue Shanfeng , Yang Wenjun
Published: August 2017

An AIE luminophore with pendent diethoxylphosphorylmethyl groups was used as solution-processed EL emitter and emitted 596 nm of orange light with peak current and external quantum efficiencies up to 9.4 cd A−1 and 3.9%, respectively.
Epanechnikov kernel for incomplete data
Authors: Mesquita D.P.P. , Gomes J.P.P. , Souza Junior A.H.
Published: August 2017

The Epanechnikov kernel (EK) is a popular kernel function that has achieved promising results in many machine learning applications. Although the EK is widely used, its basic formulation requires fully observed input feature vectors. A method is proposed to estimate the EK when these input vectors are only partially observed, i.e. some of its features are missing. In the proposed method, named expected EK, the expected value of the kernel function is estimated given the distribution of the data and the observed values of the feature vectors.
Long‐channel In0.7Ga0.3As/In0.52Al0.48As quantum‐well MOSFETs on InP substrate with record μn_eff = 6960 cm2/V‐s
Authors: Son S.‐W. , Shin S.H. , Park J.H. , Baek J.‐M. , Kim D.‐K. , Lee J.‐H. , Kim T.‐W. , Kim D.‐H.
Published: August 2017

Long‐channel In0.7Ga0.3As/In0.52Al0.48As quantum‐well (QW) metal‐oxide‐semiconductor field‐effect‐transistors (MOSFETs) on InP substrate have been fabricated and characterised. The fabricated device with Lg = 4 μm exhibits excellent maximum transconductance (gm_max) in excess of 0.48 mS/μm at VDS = 0.95 V, together with reasonably good electrostatic integrity of drain‐induced‐barrier‐lowering < 40 mV/V and subthreshold‐swing <100 mV/decade. Besides, the effective mobility (μn_eff) of the same device has been extracted, revealing that the device in this work yields excellent μn_eff = 6960 cm2/V‐s at room temperature. To the knowledge of the authors, the value of μn_eff in this work is the highest in any surface‐channel InGaAs MOSFET technology.
Intra‐operative ultrasound‐based augmented reality guidance for laparoscopic surgery
Authors: Singla Rohit , Edgcumbe Philip , Pratt Philip , Nguan Christopher , Rohling Robert
Published: August 2017

In laparoscopic surgery, the surgeon must operate with a limited field of view and reduced depth perception. This makes spatial understanding of critical structures difficult, such as an endophytic tumour in a partial nephrectomy. Such tumours yield a high complication rate of 47%, and excising them increases the risk of cutting into the kidney's collecting system. To overcome these challenges, an augmented reality guidance system is proposed. Using intra‐operative ultrasound, a single navigation aid, and surgical instrument tracking, four augmentations of guidance information are provided during tumour excision. Qualitative and quantitative system benefits are measured in simulated robot‐assisted partial nephrectomies. Robot‐to‐camera calibration achieved a total registration error of 1.0 ± 0.4 mm while the total system error is 2.5 ± 0.5 mm. The system significantly reduced healthy tissue excised from an average (±standard deviation) of 30.6 ± 5.5 to 17.5 ± 2.4 cm3 (p < 0.05) and reduced the depth from the tumor underside to cut from an average (±standard deviation) of 10.2 ± 4.1 to 3.3 ± 2.3 mm (p < 0.05). Further evaluation is required in vivo, but the system has promising potential to reduce the amount of healthy parenchymal tissue excised.
On finite‐level dynamic quantisation of event‐triggered networked systems with actuator fault
Authors: Duan Kai , Cai Yunze , He Xing , Zhang Weidong
Published: August 2017

This study addresses the networked control problem for event‐triggered systems with quantisation effect and actuator fault. A new type of finite‐level dynamic logarithmic quantiser is proposed here. Firstly, when the actuator is subjected to deterministic fault and time delay occurs in the network between the sensor and the controller, stability analysis and stabilisation of the system are accomplished. Secondly, suppose the actuator is subjected to stochastic fault and there is packet dropout in the network between the sensor and the controller, the asymptotic stability of the system is analysed, and a mean‐square feedback controller is designed. Finally, simulation studies are made to verify the effectiveness of the presented method.
Force and torque model utilising transfer‐matrix theory for a novel electrodynamic suspension reaction sphere
Authors: Chen Anlin , Zhang Ming , Zhu Yu , Huai Zhouyu , Yang Kaiming , Hu Chuxiong , Hu Jinchun
Published: August 2017

This study presents a force and torque model utilising transfer‐matrix theory for a novel electrodynamic suspension reaction sphere (EDSRS), which features a compact structure and low cost. A motor in the EDSRS is unfolded along the directions of the circumference and the arc of the stator iron core, then it can be regarded as a non‐back‐iron linear induction motor (NBILIM) with infinite length in the longitudinal direction. The NBILIM is simplified and extended by arranging infinite duplicates side by side along the transverse direction, constructing an extended simplified linear induction motor (ESLIM). Applying the transfer‐matrix theory to each layer of the ESLIM, the relationship between the magnetic fields at two boundaries is obtained, and corresponding boundary conditions are presented. An analytical model is derived based on the magnetic field. Furthermore, the errors of this analytical model are analysed and modified coefficients are obtained from finite element method (FEM) simulation. A modified model of the EDSRS is developed according to the analytical model. Finally, the proposed model is verified by FEM simulations and experiments on a prototype, and a suspension and rotation experiment is conducted.
Driving risk status prediction using Bayesian networks and logistic regression
Authors: Yan Lixin , Huang Zhen , Zhang Yishi , Zhang Liyan , Zhu Dunyao , Ran Bin
Published: August 2017

The ability to identify driving risk status plays an important role for reducing the number of traffic accidents. Bayesian networks (BNs) was applied to extract the main factors that significantly influence driving risk status. Five factors (driver state, sex, experience, vehicle state, and environment) were selected and considered to significantly influence driving risk status based on driving simulation experiments. Next, a logistic regression algorithm was employed to establish the driving risk status prediction model, and the receiver operating characteristic curve was adopted to evaluate the performance of the prediction model. The area under the curve was 0.903, indicating that the prediction model was both adaptable and practical. In addition, this study also compared three different models, namely modelling directly, modelling based on expert experience, and modelling based on BN. The results indicated that modelling based on BN outperformed all other methods. The conclusions could provide reference evidence for driver training and the development of danger warning products to significantly contribute to traffic safety.
Road network abstraction approach for traffic analysis: framework and numerical analysis
Authors: Zhu Lei , Chiu Yi‐Chang , Chen Yuche
Published: August 2017

Traffic analysis road networks are extensively used in transportation planning and modelling practice. Due to computational complexity and burden, a traffic analysis road network is a subset network which usually selected from a full‐size network. However, the process of subjectively choosing traffic analysis road network is problematic and may result in an unrepresentative road network which is useless for transportation analysis applications. This research targets on proposing a road network abstraction method that can scientifically and systematically select a representative road network from original full‐size network to achieve both representativeness and computation efficiency in various transportation and traffic analysis applications. The road networks on dynamic traffic assignment and simulation model are the interests. At the same time, traffic analysis performance metrics, such as average travel time, vehicle routing choices, and volume, are chosen as the criteria to determine the abstracted network representativeness. A numeric experiment is conducted by implementing the method in a demonstrated Alexandria network scenario. The results indicate that the proposed method is very promising. The traffic analysis performance of the abstracted network is similar to the performance of the full‐size network. However, the computational time of the abstracted network is significantly lower than that of the full‐size road network.
Transient linear TEM horn array
Authors: Elmansouri Mohamed A. , Filipovic Dejan S.
Published: August 2017

This study presents an ultrawideband transverse electromagnetic (TEM) horn array with enhanced frequency‐ and time‐domain performances for high‐power transient and short‐pulse radiation applications. The proposed linear array is composed of five combined TEM horn and loop elements. The compact size, wideband performance, and low‐dispersion characteristics of the utilised element enable good time and frequency operations over more than two‐octave bandwidth. The performance of the designed array is characterised computationally and experimentally. The scanning capabilities are also demonstrated; particularly for the time‐domain operation using fidelity factor and energy patterns. Moreover, conventional frequency‐domain side lobes (SLL) reduction techniques are utilised to minimise the time‐domain radiation at undesired directions. The proposed array has VSWR<2, gain > 8 dBi, good quality radiation patterns, and SLL<−10 dB over more than 4:1 bandwidth. Excellent time‐domain performance demonstrated by high fidelity factor over the array's field of view is achieved. Time‐domain scan up to 40° is also demonstrated.
Restricted Boltzmann machine‐based cognitive protocol for secure routing in software defined wireless networks
Authors: MohanaPriya Pitchai , Shalinie Selvaraj Mercy
Published: August 2017

Secure and stable routing is a critical issue in a conventional network environment, as the control and data planes are integrated. An intelligent routing is highly essential to provide an attack free network to its intended users. The programmable software defined network is an emerging network paradigm in which the security policies and the forwarding rules are implemented in the controller via North Bound Interface. This study incorporates a cognitive neural network learning algorithm namely restricted Boltzmann machine (RBM), to detect the routing‐based distributed denial of service attacks in dynamic source routing (DSR) protocol. RBM is a stochastic and unsupervised learning algorithm that self‐learns the network conditions by using its reasoning capability and segregates malicious routes in the route cache using context‐aware trust metrics such as reputation and energy consumption implemented in North Bound Application Programming Interface. The results show that a cognitive DSR protocol provides secure routing by increased packet delivery ratio, decreased end‐to‐end delay, reduced energy consumption and accurate detection of malicious routes compared with the conventional DSR protocol.
Development of a wireless power transmission simulator based on finite‐difference time‐domain using graphics accelerators
Authors: Ishida Hiroki , Furukawa Hiroto , Kyoden Tomoaki , Tanaka Takahiro
Published: August 2017

We describe a method for simulating an electromagnetic induction type wireless power transmission (WPT) device. This simulator was based on the finite‐difference, time‐domain method. To reduce computation time, two graphics processing units (GPUs) were used as accelerators for the electromagnetic field computation. The first GPU calculated the electromagnetic field for the non‐resonance state, and the second GPU calculated the field for the resonance state. Only two physical quantities needed to be exchanged between the two GPUs: self‐inductance and the magnetic coupling coefficient. Capacitors and a load resistance were virtually connected to the coils as lumped elements. The experimental and simulation results were in good agreement. It is expected that a transient response analysis of WPT devices will become possible in the future using this simulation architecture.
Pursuit of Enantioselective Synthesis of Heterocycle-Bearing ­Stereocenters: The Development of a Stereocontrolled BINOL-­Catalyzed Conjugate Addition of Organoboron Nucleophiles
Authors: May Jeremy , Nguyen Thien , Nguyen Truong , Le Phong , Chen Po-An , Vallakati Ravikrishna
Published: August 2017

This account chronicles the iterative development of an enantioselective conjugate addition of organoboron nucleophiles to α,β-unsaturated enones and enals catalyzed by BINOL derivatives. Beginning with a specific application of this transformation to the total synthesis of the flinderole alkaloids, the transformation progressed to encompass a much larger scope of heterocycle-substituted electrophiles. The next phase saw progress toward the use of a broader scope of functional nucleophiles, with application in a strategy to synthesize discoipyrrole D. At each stage of this chronologically organized discussion, key problems, hypotheses, and solutions are presented to show the sources of discovery and solutions to problems as the catalyst and other reaction components were made more reactive. The interplay of target-directed reaction development, efforts to increase the scope of compatible functional groups, mechanistic studies, and empirical exploration is described to illustrate sources of chemical discovery.

1 Introduction

2 Synthesis of the Flinderole Natural Products

3 Indole-Bearing Stereocenters

4 Heteroaryl-Bearing Stereocenters

5 Bis-Heteroaryl Stereocenters

6 Synthetic Strategy for Discoipyrrole D

7 Bis-Aryl Stereocenters

8 Remaining Challenges

9 Conclusion
Asymmetric Desymmetrization of Substituted Cyclohexadienones by Rhodium-Catalyzed Conjugate Hydrosilylation and Theoretical Calculations of Its Mechanistic Aspects
Authors: Naganawa Yuki , Nishiyama Hisao , Ito Jun-ichi , Kawagishi Mayu
Published: August 2017

Asymmetric desymmetrization was demonstrated by means of transition-metal-catalyzed conjugate reduction with hydrosilanes as reductants. Chiral rhodium-bis(oxazolinyl)phenyl complexes [Rh(Phebox-R)] were found to be effective catalysts for conjugate hydrosilylation of differently γ,γ-disubstituted cyclohexadienones to provide the corresponding product with chiral quaternary centers. The mechanistic consideration was also performed by theoretical calculation. These attempts provided information about i) the initial activation of Rh(III) complex into Rh(I) species assisted by hydrosilanes, ii) the complete catalytic cycle, and iii) an explanation of the asymmetric induction and the difference of the structure of cyclohexadienones in enantioselectivity.
Sharpless Asymmetric Dihydroxylation on α,β-Unsaturated Diazoketones: A New Entry for the Synthesis of Disubstituted Furanones
Authors: Talero Alexánder , Burtoloso Antonio
Published: August 2017

The synthesis of enantiomerically pure 4,5-disubstituted 2-furanones is accomplished in three steps from aldehydes. The steps involve a highly enantioselective Sharpless asymmetric dihydroxylation of α,β-unsaturated diazoketones, followed by a photochemical Wolff rearrangement.
Antibiotika-Reduktion im Kälberstall
Authors: Spielberger Ulrich , Brendieck-Worm Cäcilia
Published: August 2017

In einem biologisch-dynamisch wirtschaftenden Milchviehbetrieb mit eigener Nachzucht weiblicher Tiere und Mast der Bullenkälber wurden aufgrund hoher Inzidenz von Kälberkrankheiten umfassende Maßnahmen nötig. Insbesondere traten gehäuft Atemwegserkrankungen auf, die einen hohen Antibiotika-Einsatz erforderten. Ein Stallneubau konnte die Probleme mindern aber nicht lösen. Zur Prävention wurde den Kälbern deshalb ab dem 3. Lebenstag über einen Zeitraum von 40 Tagen eine Kräutermischung mit Wirkung auf Stoffwechsel, Verdauung, Atemfunktion und Immunsystem verabreicht (PlantaPulmin S-Konzentrat, SaluVet GmbH, Bad Waldsee). Während des Beobachtungszeitraums von 28 Monaten sank die Erkrankungsrate deutlich. Gleichzeitig wurden die Krankheitsverläufe milder und beeinträchtigten die Kälber nicht in ihrer Entwicklung. Auf Antibiotika konnte wenige Monate nach Beginn der prophylaktischen Kräutergabe ganz verzichtet werden. Die Kräutergabe wurde vom Tierhalter über den Beobachtungszeitraum hinaus beibehalten. Eine tierärztliche Bestandskontrolle 6 Monate nach Ende des Beobachtungszeitraumes bestätigte den stabilen Gesundheitsstatus der Kälber.
Amerikanische Chiropraktik – eine ganzheitliche Wirbelsäulen- und Gelenktherapie
Authors: Bensinger Sylvie
Published: August 2017

Unsere Patienten werden heute in den unterschiedlichsten Bereichen eingesetzt. Je nach Beanspruchung treten Belastungen auf, durch die es zu Verletzungen (Zerrungen, Stauchungen, Frakturen) kommen kann. Viel häufiger sind aber leistungs- und auch alltagseinschränkende Veränderungen am Bewegungsapparat bzw. einzelner Strukturen, die eher unauffällig verlaufen und mit unseren schulmedizinischen Möglichkeiten häufig nicht greifbar sind. Hier können Diagnostik und Therapie durch spezialisierte Veterinär-Chiropraktiker helfen, den Tieren ihre gewohnte Lebensqualität und Leistungsfähigkeit wieder zurückzugeben.
Ein Lycopodium-Fall einmal anders
Authors: von Kriegsheim Ada
Published: August 2017

Der Fallbericht zeigt die tiefe Wirkung eines homöopathischen Arzneimittels. Der Hund „Benni“ leidet unter länger bestehenden Rückenproblemen sowie Verhaltensveränderungen und wird mit einer Gabe Lycopodium behandelt. Zehn Tage nach der Anwendung des Arzneimittels wandelt sich der Hund von einem zurückhaltenden, melancholischen Patienten mit Rückenschmerzen zu einem fröhlichen Hund ohne Beschwerden. Selbst 1,5 Jahre später ist der Hund beschwerdefrei. Diskutiert wird in diesem Fall das angewendete Arzneimittel Lycopodium und die Heringʼsche Regel.
Gordon Setter mit hochgradigem Ikterus und Herzinsuffizienz
Authors: Danowski Klaus
Published: August 2017

Es wird ein 10-jähriger Gordon Setter mit Herzinsuffizienz und schwerem Ikterus vorgestellt. Durch Arsenicum album kann die akut lebensbedrohliche degenerative Pathologie mit starken Schmerzen, intensivem Fieber und Lungenödem aufgefangen werden. Die sehr breite Wirkung von homöopathischem Digitalis wird an dem Rückgang von Herzinsuffizienz, Ikterus und Leberschwellung deutlich. Gemütssymptome, insbesondere die Furcht vor Alleinsein in Kombination mit nächtlicher Ruhelosigkeit, erlauben eine langfristige konstitutionelle Stabilisierung mit Arsenicum album.
Entwicklung einer nicht arteriitischen anterioren ischämischen Optikusneuropathie am ursprünglich gesunden Partnerauge bei den mit systemischen Kortikoidenbehandelten Patienten
Authors: Pahor Artur , Pahor Dusica
Published: August 2017

Hintergrund Das Ziel unserer prospektiven Pilotstudie war es, Ergebnisse der systemischen Kortikosteroidtherapie bei Patienten mit nicht arteriitischer anteriorer ischämischer Optikusneuropathie (NAION) während eines Beobachtungszeitraums von 1 Jahr zu bewerten und die NAION-Inzidenz im zunächst gesunden Partnerauge bei diesen Patienten festzustellen.

Patienten und Methoden Alle mit akuter NAION diagnostizierten Patienten, die auf unserer Station während 2014 aufgenommen wurden und alle Einschlusskriterien für eine systemische Kortikosteroidtherapie erfüllten, wurden in die Studie eingeschlossen. Die Einschlusskriterien waren eine korrigierte Sehschärfe von 0,3 oder weniger und eine Krankheitsdauer von weniger als 2 Wochen. Alle Patienten wurden von einem Rheumatologen untersucht sowie einer kompletten Augenuntersuchung unterzogen, einschließlich einer Fluoreszenzangiografie und einer Gesichtsfelduntersuchung. Von 23 Patienten konnten nur 3 Patienten unsere Einschlusskriterien zur Kortikosteroidbehandlung erfüllen und dann behandelt werden. Zehn Patienten dienten als Kontrolle. Bei der Behandlung benutzte man einen Therapieplan mit einer Initialdosis von 80 mg Prednisolon während der ersten 2 Wochen und dann wurde die Behandlung in 3 – 4 Monaten ausgeschlichen.

Ergebnisse Die durchschnittliche bestkorrigierte Sehschärfe bei der Aufnahme betrug 0,12, nach 1 Jahr 0,35. Die durchschnittliche Behandlungsdauer betrug 3,3 Monate. Nachdem die Behandlung nach 5 – 6 Monaten abgesetzt wurde oder 8 – 9 Monate nach der 1. Untersuchung, kam es bei allen Patienten zur Entwicklung einer NAION am Partnerauge. Die durchschnittliche Sehschärfe am Partnerauge betrug 0,73, nach 4-monatiger Nachbeobachtungszeit wurde bei 2 Patienten eine Sehschärfe von 1,0 und bei 1 Patienten eine Verringerung von 0,8 auf 0,4 beobachtet. Für das 2. Auge wurde keine Steroidbehandlung eingeleitet. In der Kontrollgruppe trat am Partnerauge kein NAION auf.

Schlussfolgerung Kortikosteroidbehandlung trägt zur Verbesserung des Visusergebnisses bei allen Patienten mit NAION bei, wenn man sie mit unbehandelten Partneraugen vergleicht, bei denen es bei 1 Patienten zur Verringerung der Sehschärfe gekommen ist. Unsere Studie bestätigte, dass die Kortikosteroidbehandlung ein prädisponierender Faktor für die Entwicklung der NAION am Partnerauge sein könnte. Weitere Studien mit größerer Patientenzahl sind erforderlich, um unsere Ergebnisse zu bestätigen.
Schwere Gelbfieber-impfassoziierte Erkrankung: ein Fallbericht und aktuelle Übersicht
Authors: Slesak Günther , Gabriel Martin , Domingo Cristina , Schäfer Johannes
Published: August 2017

Anamnese und klinischer Befund 5 Tage nach einer Gelbfieber (GF)-Impfung traten bei einem 56-jährigen Mann hohes Fieber auf mit starken Kopfschmerzen, Abgeschlagenheit, Konzentrationsstörungen und Exanthem.

Laboruntersuchungen Die Leberwerte und GF-Antikörperreaktion waren deutlich erhöht. Im Urin war mittels PCR GF-Impfvirus nachweisbar.

Diagnose und Therapie Es wurde zunächst eine schwere GF-Impfvirus-assoziierte viszerotrope Erkrankung vermutet und symptomatisch behandelt.

Verlauf Das Fieber sistierte nach insgesamt 10 Tagen, Organversagen traten keine auf. Es bestanden jedoch noch über 3 Monate postenzephalitische Beschwerden mit Abgeschlagenheit, Konzentrations-, Gedächtnis- und Leseschwächen und nur teilweiser Arbeitsfähigkeit, sodass der Verdacht auf eine neurotrope GF-impfassoziierte Erkrankung besteht.

Folgerung Schwere Impfnebenwirkungen müssen bei der Indikationsstellung zur GF-Impfung bedacht werden.
High-Frequency Trading and its Role in Fragmented Markets
Authors: Haferkorn Martin
Published: August 2017

Securities trading underwent a major transformation within the last decade. This transformation was mainly driven by the regulatory induced fragmentation and by the increase of high-frequency trading (HFT). On the basis of the electronic market hypothesis, which poses that coordination costs decline when markets become automated, and the efficient market hypothesis in its semi-strong form, we study the effect of HFT on market efficiency in the European fragmented market landscape. In doing so, we further incorporate the realm of financialization, which criticizes the increase in transaction speed. By conducting a long-term analysis of CAC 40 securities, we find that HFT increases market efficiency by leveling midpoints between Euronext Paris and Bats Chi-X Europe. On the basis of a crosscountry event study, we analyze the effect of the German HFT Act. We observe that the midpoint dispersion of blue chip securities between the two leading venues Deutsche Boerse and Bats Chi-X Europe increased. We conclude that HFT increases market efficiency in the European market landscape by transmitting information between distant markets.
Orbital angular momentum eigenfunctions for fast and numerically stable evaluations of closed-form pseudopotential matrix elements
Authors: Hu Anguang , Chan Nora W. C. , Dunlap Brett I.
Published: August 2017

The computation of s-type Gaussian pseudopotential matrix elements involving low powers of the distance from the pseudopotential center using Gaussian orbitals can be reduced to familiar integrals. They may be directly expressed as either simple three-center overlap integrals for even powers of the radial distance from the pseudopotential center or related to the three-center nuclear integrals of a Gaussian charge distribution for odd powers. Orbital angular momentum about each atom is added to these integrals by solid-harmonic differentiation with respect to its center. The solid-harmonic addition theorem allows all the integrals to be factored into products of invariant one-dimensional integrals involving the Gaussian exponents and angular factors that contain the azimuthal quantum numbers but are independent of all Gaussian exponents. Precomputing the angular factors allow looping over all Gaussian exponents about the three centers. The fact that solid harmonics are eigenstates of angular momentum removes the singularities seen in previous treatments of pseudopotential matrix elements.
Dynamics and cluster formation in charged and uncharged Ficoll70 solutions
Authors: Palit Swomitra , Yethiraj Anand
Published: August 2017

We apply pulsed-field-gradient NMR (PFG NMR) technique to measure the translational diffusion for both uncharged and charged polysaccharide (Ficoll70) in water. Analysis of the data indicates that the NMR signal attenuation above a certain packing fraction can be adequately fitted with a bi-exponential function. The self-diffusion measurements also show that the Ficoll70, an often-used compact, spherical polysucrose molecule, is itself nonideal, exhibiting signs of both softness and attractive interactions in the form of a stable suspension consisting of monomers and clusters. Further, we can quantify the fraction of monomers and clusters. This work strengthens the picture of the existence of a bound water layer within and around a porous Ficoll70 particle.
Note: Guaranteed collocated multimode control of an atomic force microscope cantilever using on-chip piezoelectric actuation and sensing
Authors: Ruppert Michael G. , Yong Yuen K.
Published: August 2017

The quality (Q) factor is an important parameter of the resonance of the microcantilever as it determines both imaging bandwidth and force sensitivity. The ability to control the Q factor of multiple modes is believed to be of great benefit for atomic force microscopy techniques involving multiple eigenmodes. In this paper, we propose a novel cantilever design employing multiple piezoelectric transducers which are used for separated actuation and sensing, leading to guaranteed collocation of the first eight eigenmodes up to 3 MHz. The design minimizes the feedthrough usually observed with these systems by incorporating a guard trace on the cantilever chip. As a result, a multimode Q controller is demonstrated to be able to modify the quality factor of the first two eigenmodes over up to four orders of magnitude without sacrificing robust stability.
Self-catalyzed core-shell GaAs/GaNAs nanowires grown on patterned Si (111) by gas-source molecular beam epitaxy
Authors: La Rui , Liu Ren , Yao Weichuan , Chen Renjie , Jansson Mattias , Pan Janet L. , Buyanova Irina A. , Xiang Jie , Dayeh Shadi A. , Tu Charles W.
Published: August 2017

We report structural studies on the epitaxial growth of GaAs/GaNAs core-shell nanowires (NWs) on patterned Si (111) substrates by self-catalyzed selective area growth using Gas-Source Molecular Beam Epitaxy. Epitaxial growth conditions were obtained using a combination of dry and time-sensitive wet etching of the SiO2 growth mask and native SiO2 layer, respectively. We found that higher growth temperatures resulted in a higher yield for the epitaxial growth of patterned self-catalyzed GaAs NWs on Si with an optimal temperature of 690 °C. The GaNAs shell growth at 500 °C was found to be conformal and maintained an epitaxial and dislocation-free interface with both the Si substrate and the GaAs nanowire. The micro-photoluminescence (μ-PL) measurement at 6 K revealed two bands peaking at 1.45 and 1.17 eV, which could be emission from the GaAs core and GaNAs shell. Transmission electron microscopy showed the zincblende crystal structure of GaAs and GaAs/GaNAs core-shell NWs with minimal twinning near the base of the GaAs nanowires and at the tips of the GaAs/GaNAs core/shell nanowires. This study illustrates the feasibility of the epitaxial growth of patterned GaAs with dilute nitride shells on Si substrates, which would have potential for Si-friendly intermediate band solar cells and telecom emitters.