bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental methods of teaching computer graphics and design: Impact on the creative potential of higher education students
Authors: Mosendz Oksana , Borysova Svitlana , Vitchynkina Kateryna , Brovchenko Anatolii , Kovalchuk Ostap
Published: February 2025

Introduction: The increasing global reliance on digital tools has elevated the demand for specialists adept in computer graphics and design, emphasizing the need for creative thinking and graphic competence. This study investigates the impact of experimental methods for teaching computer graphics and design on fostering the creative potential of higher education students.Objectives: The primary objectives include defining key concepts like "graphic competence," outlining its components, identifying stages of professional training, and evaluating the content, forms, methods, and tools used in developing graphic competence.Methods: A mixed-methods approach was employed, combining theoretical analysis of educational models and practical experimentation in classroom settings. Data was collected through surveys, portfolio assessments, and reflective journals.Results: The findings highlight that incorporating activity-based, competence-oriented, and creative approaches significantly enhances students’ motivation, spatial imagination, reflection, empathy, and aesthetic taste. The staged training model—comprising search and research, practical and artistic, and formative phases—proved effective in cultivating graphic competence. Key results also show that integrating modern design software, such as Adobe Creative Suite and Blender, alongside tailored pedagogical methods, leads to improved professional readiness and innovative thinking.Conclusions: In conclusion, the study underscores the transformative role of experimental teaching methods in shaping not only the professional skills but also the creative self-awareness of students. These findings contribute to the ongoing discourse on designing effective educational frameworks for creative disciplines.
Evaluating Digitalization as a Core Requirement for Future Educational Systems
Authors: Ivanenko Nadiya , Rud Anatolii , Hurbanska Antonina , Cheban Yuliia , Syrtseva Svitlana
Published: February 2025

Today, the view of modern technologies as mere tools for various purposes in learning and knowledge exchange is being rethought. This reassessment opens up the possibility of new approaches to education that stem from the philosophy of technology and sociology. The interpretation of the latest technologies in the education of the future justifies the need for new educational approaches. The purpose of this paper is to analyse the possibility of integrating new technologies into the processes of learning and education, knowledge production and educational institutions within the framework of digitalisation. Materials and The study examined the latest scientific sources related to this topic using international scientific and metric databases such as Web of Science, Scopus, Google Scholar. The results of the study showed that new technologies are not just tools or external layers added to education. In their social and natural aspects, they mediate almost all human experiences and even influence the formation of people's worldviews. We conclude that the interaction between people and new technologies is a set of inseparable components that cannot exist independently. At the same time, the educational interpretation of the latest technologies considers them as mediators of experience. In particular, these technologies tend to change both the forms and content of future education. Any impact that results from this interaction affects the behaviour of individuals in society, as well as the general perception of the social and natural environment.
Examining Integration Opportunities for the Ukrainian Economy in International Relations During Martial Law
Authors: Kampo Ilda , Abramova Maryna , Savitskaya Maryia , Shaulko Yaroslav , Volchenko Nataliia
Published: February 2025

Introduction: Martial law creates global instability, imposes limitations on commercial activities, and discourages international investment due to insecurity and restricted movement. This study examines the potential for Ukraine's economy to achieve global integration under martial law conditions.Objective: The purpose of the study is to determine the consequences of digitalization and geopolitical challenges on Ukraine’s economic integration and its international relations during martial law.Methods: The research utilized academic databases, scholarly publications, reports from international institutions and Ukrainian governmental bodies, and critical analysis of affiliated organizational websites. This comprehensive methodology ensured a robust investigation of economic integration strategies.Results: The findings reveal that strategic collaboration with international institutions and allied nations can mitigate the negative impacts of martial law. International aid supports infrastructure reconstruction and stimulates economic growth. Diplomatic initiatives foster trade agreements and strengthen global links, while digitalization provides innovative solutions to infrastructure challenges and facilitates access to remote markets. Additionally, agricultural and ecological initiatives are identified as key contributors to economic recovery.Conclusions: The study underscores the importance of economic and foreign policies in driving growth during martial law. A strategic plan focused on international collaboration, foreign aid, diplomacy, and digitalization is vital for post-war reconstruction. Policy recommendations include cautious restoration of infrastructure, fostering innovation-driven economic growth, developing digitalized systems, promoting trade agreements, supporting local businesses, and attracting investment through corporate strategies. Diplomatic efforts are essential for securing overseas aid and enhancing global trade relationships, paving the way for Ukraine's economic integration on a global scale.
REDUCTION OF ZEBRA CHIP INFECTION SYMPTOMS IN POTATO
Authors: Martinez-Gutierrez Ricardo , Mora Herrera Martha Elena , Trejo Carlos , Almeyda-Leon Isidro Humberto , Lopez-Delgado Humberto Antonio
Published: February 2025

Background: There have been few studies on the long-term effects of hydrogen peroxide and dehydroascorbate (H2O2 and DHA) on biotic stress, especially in potato plants infected with Candidatus Liberibacter solanacearum (Lso) that cause the Zebra chip disease, characterized by browning of the tubers, reduced productivity and anomalies in the morphology of the plant. Objective: To evaluate the long-term effects of DHA and H2O2 treatments on the reduction of symptoms in potato plants infected with Lso. This research was realized at the INIFAP facilities at Experimental Site Metepec, Mexico State. Methodology: Single nodes were waterlogged in DHA, H2O2, or distilled water, followed by culture in Murashige and Skoog medium (MS), and microplants obtained were transplanted in greenhouse conditions. Seventy-three days after transplanting, leaf water potential (Yw), chlorophyll, H2O2 content, and catalase activity (CAT) were determined. Results: DHA significantly increased minituber weight and chlorophyll content in the long term. It also, reduced H2O2 content and increased CAT in infected plants, resulting in increased minituber weight. A long-term effect of H2O2 was observed, as it induced significant increases in stem height, shoot fresh and dry weight, relative chlorophyll content, and minituber weight. Implications: DHA and H2O2 participated as signal molecules, triggering physiological changes promoting increases in productivity in plants infected with Lso, justifying the importance of the study of these molecules under biotic stress conditions. Conclusion: Long-term effects of H2O2 and DHA on the amelioration of symptoms of potato Zebra chip associated with Lso solanacearum were demonstrated.

 
DIVERSIDAD FENOTÍPICA Y CALIDAD DE FRUTO DE JITOMATE CRIOLLO (Solanum lycopersicum L.) DEL SURESTE DE MÉXICO
Authors: Ortiz-Salazar Genny Carolina , Andueza-Noh Rubén Humberto , Lara-Martín Alicia Ruby , Medina-Dzul Kati Beatriz , Castañón-Nájera Guillermo , Díaz-Mayo Juan , Latournerie-Moreno Luis
Published: February 2025

Background. Mexico is the center of domestication and diversity of tomato (Solanum lycopersicum L.). Its crop is widely distributed in the country; therefore, it is important to know the diversity that farmers manage and conserve in Southeastern Mexico to use sustainably this plant genetic resource. Objective. To characterize the phenotypic variation and nutritional quality of landrace tomatoes from Southeastern Mexico. Methodology. From May to June 2018, 34 landrace populations of tomato were collected in different states of Southeastern Mexico: 24 from Yucatan, six from Chiapas, two from Tabasco, and two from Campeche. Phenotypic characterization of the tomato populations included 26 descriptors for plant, inflorescence, and fruit. For the evaluation of nutritional quality, the content of water, crude fiber, protein, lipids, ash, and nitrogen free extract (NFE). Results. Based on principal component analysis, the first three components explained 73.82% of the phenotypic variation in tomato populations. The first two principal components were distributed in three well-defined groups, and three populations were separated individually by distinctive characteristics mostly of the fruit descriptors (fruit shape, fruit size and number of locules of fruits). The phenotypic diversity was distributed mainly in relation to fruit shape and fruit size. Regarding the nutritional quality of the fruits, the tomato populations Y116 and Y127 had high protein content (17.71% each) and ash content (12.07% and 11.43%, respectively). These populations were collected in Yucatan and had the largest fruit size and kidney-shaped fruits. Implications. The exploratory study of the diversity and fruit nutritional quality of landrace tomatoes allowed the identification of populations with agronomic potential for a genetic improvement program of fruit yield and fruit quality of landrace tomato. Conclusions. The highest phenotypic variation among landrace tomato populations was observed in fruit descriptors (color of ripe fruits, fruit shape, fruit size, fruit weight, number of locules of fruits, and fruit yield). The tomato populations Y116, Y127, Y128, Y130 and T106 had high content of protein, ash, lipid and crude fiber.
CARACTERISTICAS DE LA CANAL Y CALIDAD DE LA CARNE DE CONEJOS SUPLEMENTADOS CON ZINC METIONINA O PIGMENTO DE FLOR DE CEMPASÚCHIL CON DOS EDADES AL SACRIFICIO
Authors: Garcia Martinez Pablo Antonio , Sánchez Torres Juan Edrei , Dominguez Vara Ignacio Arturo , Morales Almaraz Ernesto , Galeano Diaz Johana Paola , Mejia Uribe Luis Alberto , Valladares Carranza Benjamin , Ramirez Bribiesca Jacinto Efrén
Published: February 2025

Background: The consumption per capita of rabbit meat in Mexico is limited (120g) due to the lack of information among consumers about the nutritional quality of rabbit meat, and at the same time, to the appearance of color, since they prefer a redder meat with more intramuscular fat. Objective: To evaluate the effect of the addition of Zinc-Methionine (Zn-Met), marigold flower pigment (FC) and two slaughter ages (MS) on carcass characteristics and meat quality in rabbits. Methodology: A total of two hundred 40-day-old rabbits (New Zealand X California, 1124±48 g initial live weight) were randomly assigned to one of 4 experimental diets and two fattening periods (68 and 82 days of age), using a completely randomized experimental design with a 2 x 2 x 2 factorial design. The control diet contained no additives, the second diet contained 200mg/kg-1 Zinc Methionine (Zn-Met), the third diet contained 80 mg/kg-1 marigold flower pigment (FC) and the fourth diet (Zn-Met*FC) contained both additives (200mg/kg-1 Zn-Met and 80 mg/kg-1 FC). The color, pH, meat-bone-to-dissectible fat ratio, water loss by cooking, shear strength and nutritional quality of rabbit meat were measured in the Longissimus thoracis et lumborum (LTL) muscle. Results: In meat color, L* values showed interactions (P < 0.05) between Zn-Met*EM and FC*EM; interaction was observed for carcass bone weight (g) (P < 0.05) between Zn-Met*FC, finding higher values (P < 0.05) in rabbits slaughtered at 82 d of age (g and %). With respect to the amount of dissectible adipose content of the carcass (g and %), there was interaction between Zn-Met*EM (P<0.05), with the highest values found in rabbits killed at 82 d (P<0.05). On the other hand, there was interaction in crude protein content (g/100g-1) (P<0.05) between Zn-Met,*FC*EM; while in moisture content and ethereal extract (g/100g-1) there was a difference (P<0.05) between animals slaughtered at different ages. MS increased the saturated fatty acid (SFA) content, while in the monounsaturated fatty acid (MUFA) content there was an interaction between Zn-Met*MS (P<0.05), with rabbits killed at 82 d of age presenting the highest values (P<0.05). Implications: The addition of Zn-Met modifies the fatty acid profile of meat in cattle and sheep, while the FC pigment modifies the color of poultry meat; however, the addition of these additives has not been studied in rabbits. Conclusion: The inclusion of Zn-Met, FC at two ages at slaughter modifies meat color and nutritional composition of rabbit meat.
TOLERANCIA A CADMIO Y RESISTENCIA AL DAÑO POR Bemisia tabaci INDUCIDA POR UN CONSORCIO DE HONGOS MICORRÍZICOS ARBUSCULARES EN Solanum lycopersicum L.
Authors: Amaya-Martin Shirley Margarita , Ballina-Gomez Horacio Salomon , Alvarado-López Carlos Juan , Ruiz-Sánchez Esau , Gil-Cardeza Maria Lourdes , Azcorra-Perera Gabriel De Jesus
Published: February 2025

Background. Cadmium (Cd) is a potentially toxic element that when released in permeable soils such as those of Yucatan enters directly into the horticultural systems and in general into the food web causing several problems. It is known that tomato (Solanum lycopersicum L.) shows tolerance to the element cadmium and resistance to damage by various pests, however, the biological mechanism that is triggered in its interaction with microorganisms under this type of stress conditions is little known. Objective. To analyze the effect of a consortium of arbuscular mycorrhizal fungi on Cd tolerance and resistance to B. tabaci damage in S. lycopersicum L. Methodology. A split-plot design was used with the following factors: 1) mycorrhizal fungal consortium: control (M–) and mycorrhizal fungal (M+); 2) damage by B. tabaci: control (D-) and presence (D+); and 3) addition of Cd at three levels: control (C), Cd at 0.005 ppm (Cd+) and Cd at 0.020 ppm (Cd++). Mycorrhization, growth and plant defense were estimated. Results. Colonization of 39% and 49% was found, even with the addition of Cd+ and Cd++, respectively. Likewise, positive effects of mycorrhizal fungi on plant height growth and leaf thickness were recorded, interestingly despite the addition of cadmium. Also, compensatory growth responses in terms of leaflet production were recorded, but in the absence of mycorrhizal fungi and in the presence of B. tabaci. Additionally, the mycorrhizal fungi produced less hard leaves in the presence of B. tabaci, which suggests an effect of an improvement in the nutritional quality of the leaves. Implications. Plant growth of tomato plants could be as result of inherent plant growth more than other extrinsically factors such as cadmium or B. tabaci. Conclusions. Tomato plants showed positive effects on cadmium tolerance and resistance to damage by B. tabaci, although inherent plant growth could be a very important mechanism to be considered in the future.
REVISIÓN SISTEMÁTICA SOBRE LA EFECTIVIDAD DE CETOENOLES Y SU MECANISMO DE RESISTENCIA EN ÁCAROS FITOFAGOS DE LA FAMILIA TETRANYCHIDAE
Authors: Hernández Núñez Emanuel , Ruiz Sanchez Esau , Dzib Cauich Dany Alejandro , Cua Basulto Marcos
Published: February 2025

Background. Ketoenol acaricides exert their action by inhibiting Acetyl-CoA carboxylase (ACC). These acaricides have been highly effective for the management of phytophagous mites, however, their intensive use has generated resistant populations, which is why it is necessary to know what resistance mechanisms could be involved in mites of the Tetranychidae family in greenhouse and field conditions. Methodology. A literature review of ketoenolic acaricides was performed in the following databases: Google academic, Science Direct & Springer, for which word combinations were used such as: ketoenolic acaricides, tetronic and tetramic acid, spiromesifen, spirodiclofen, effectiveness of ketoenols, resistance mechanisms. Based on these parameters, 68 bibliographic references were selected, taking into consideration whether the studies had been carried out from year 2000 until 2023. To process the data from the publications, it was organized in the Microsoft Office Excel® program, where the information related to the effectiveness of ketoenolic acaricides and the resistance mechanisms of mites of the Tetranychidae family were classified, analyzed and discussed. Main findings. The use of Ketoenolic acaricides are an effective alternative in suppressing the population density of phytophagous mites of the Tetranychidae family in greenhouses and fields, taking into account that they are effective when applied at low or intermediate doses; likewise, the effectiveness of ketoenolic acaricides is not affected if they are applied in greenhouse and field conditions since their effectiveness is greater than 85%. On the other hand, resistance to ketoenolic acaricides is mainly mediated by metabolic resistance, due to high levels of activity of detoxification enzymes (P-450 monooxygenases, esterases and glutathione S-transferases) that the selected populations present. Regarding resistance at the site of action, there are few recorded cases, therefore, it is not considered an important factor in resistance to ketoenol acaricides in Tetranychidae. Implications. It is essential to know the mechanism of resistance to acaricides in Tetranychidae management programs, establishing more efficient measures on the use of chemical acaricides, such as a good application of acaricides to crops and rotation of acaricides, in this way we will contribute to a lower resistance to mites. Conclusion. This review indicates that ketoenolic acaricides are effective for control in mites, however, resistance to ketoenols in mites of the Tetranychidae family is mediated in most cases by detoxification enzymes.
ESTIMACIÓN DE METABOLITOS SECUNDARIOS Y EMISIONES DE METANO EN ENSILADOS DE SORGO
Authors: Rosas-Davila Melchor , Morales-Almaraz Ernesto , Lopez-Gonzalez Felipe , Arriaga-Jordan Carlos Manuel
Published: February 2025

Background. Feeding cattle in small-scale silage-based dairy production systems can improve their production efficiency while reducing greenhouse gas emissions. Objective. To determine the effect of partial replacement of corn silage with sorghum silage on the concentration of secondary metabolites in terms of Total Phenols (TP), Total Tannins (TT), and Condensed Tannins (CT), as well as to estimate methane (CH4) and carbon dioxide (CO2) emissions. Methodology. The treatments were analyzed with a split-plot experimental design where the treatments (main plot) were; T1 = 50% sorghum silage cv Top Green + 50% corn silage, T2 = 50% sorghum silage cv Caña Dulce + 50% corn silage, T3 = 100% corn silage cv Cenzontle (control), and the measurement periods were the minor plots. Results. Inclusion of sorghum silage decreased enteric methane and carbon dioxide emissions (P<0.05), even though the concentration of phytochemical compounds among cultivars was not variable (P>0.05). Implications. Understanding the impact of changing forage chemical composition on reducing greenhouse gas (GHG) emissions in dairy systems is an important issue for mitigating climate change. Conclusions. The inclusion of sorghum silage in this study slightly reduced enteric methane and carbon dioxide emissions. Under these conditions, it is suggested that more information be provided on greenhouse gas emission factors and mitigation strategies in small-scale production systems.
INFLUENCIA DE LAS ÁREAS GANADERAS SOBRE LAS COMUNIDADES DE AVES EN EL NORTE DE VERACRUZ, MÉXICO
Authors: Cipriano Anastasio Juan , Sáenz Lorenzo Carlos , Balderas Mancilla Ulises De Jesus , Argüelles Jiménez Jimmy
Published: February 2025

Background. Livestock activities generate changes in ecosystems that impact bird communities, which fulfill diverse ecological functions such as pollination, fruit and seed dispersal, and biological control of insects and/or pests. Objective. To characterize the community of birds in a livestock landscape in northern Veracruz. Methodology. From 2020 to 2021, 144 visits were made to live fences (CV; n = 3) and cattle pastures (PA; n = 3), where the fixed-radius point count technique was used to identify and count the birds present. Results. A total of 6,450 individuals and 107 species were recorded. In general, the CVs were more diverse than the PAs, although the PAs were more dominant. The importance value index reflects that in the VCs the importance of the species is similar, while in the PAs certain species stand out, however, at the level of trophic guilds, insectivorous birds dominate. Through a canonical correspondence analysis, three community assemblages were distinguished: one station in the VCs, one station in the APs and the rest of the stations. Implications. The work suggests further studies that will allow us to know why birds are using these man-made livestock systems. Conclusion. The live fences obtained greater diversity, so it is necessary to integrate more trees within the pastures to increase the ecological functions, such as the control of insects through insectivorous birds.
INTENCIÓN DE PRODUCTORES DE LECHE DE VACA PARA USAR ENSILADO DE MAÍZ, Y EL PAPEL DE LA RED DE AMISTAD EN LA COMUNICACIÓN DE LA INNOVACIÓN
Authors: Plata-Reyes Dalia Andrea , Estrada-Flores Julieta Gertrudis , Rayas-Amor Adolfo Armando , García Carlos Galdino Martínez
Published: February 2025

Background: The adoption of agricultural technologies, such as maize silage is influenced by various factors, as highlighted by studies based on the Theory of Reasoned Action and the Theory of Planned Behaviour. These theories identify key determinants of technology adoption among small-scale dairy farmers in central Mexico, including characteristics like age, experience and production unit conditions. Objective: The aim of this work is to identify factors influencing small-scale dairy farmers to adopt corn silage and to explore the role of their friendship networks in spreading innovation. Methodology: The study was conducted in the municipality of Aculco, State of Mexico. The information was collected through a questionnaire administered to 106 farmers, who were selected through snowball sampling method. Farmers' intention and the three components of the Theory of Planned Behaviour (TPB): Attitude, Subjective Norm, and Perceived Behavioural Control, were measured using a five-point Likert scale. A hierarchical multiple regression model was conducted to analysed the data. To identify the friendship network among farmers, a binary symmetric matrix was created. It is characterized by an equal number of rows and columns. Each cell contains a value of 1 or 0, where 1 indicates the presence of friendship and 0 indicates absence. The Social Network Analysis (SNA) identified key actors for innovation diffusion based on centrality measures such as degree, betweenness, and closeness. Results: Dairy farmers' intention to adopt maize silage were influenced by their beliefs about the innovation, social referents, age, and the number of lactating cows. A lack of knowledge and training was identified as a significant constraint. Additionally, 79% of farmers were involved in the friendship network. Implications: Two key nodes in the network were identified as potential drivers for disseminating information to other farmers. These individuals could play an important role in promoting maize silage adoption among those who have not yet implemented the innovation. Conclusions: Farmers' intentions were shaped by beliefs, social referents, age, and the number of lactating cows. Additionally, friendship networks emerged as a valuable channel for communicating and spreading information about maize silage adoption, highlighting the importance of social connections in agricultural innovation.
COMBINING ALLOMETRY AND UNMANNED AERIAL VEHICLE TO ESTIMATE ABOVEGROUND BIOMASS AT THE INDIVIDUAL TREE LEVEL
Authors: Pompa-García Marín , Padilla-Martínez Jaime Roberto , Vivar-Vivar Eduardo Daniel , Yerena-Yamallel Jose Israel
Published: February 2025

Background: Forest ecosystems are sources of environmental services, not least their considerable capacity to sequester large amounts of carbon. Accurate measurements of aboveground biomass (AGB) are therefore gaining importance in the models implemented by climate change mitigation initiatives. Objective: To estimate the aboveground biomass of individual trees using allometric and photogrammetric techniques, with total tree height (TH) as a predictor variable calculated from images obtained by unmanned aerial vehicles (UAV). Methodology: The experiment included a natural stand of mixed and uneven-aged forest (PAW) and a forestry plantation (REB) as strategic areas to contribute to refining the knowledge regarding AGB estimation. Combining field data with the use of a DJI Phantom 4 Multispectral UAV, we explored TH as a predictor variable of AGB using regression procedures. Results: In the PAW were classified four genera: Pinus, Quercus, Arbutus, and Juniperus, the first was the most abundant genus. On the other hand, the REB site is composed of Pinus arizonica. Consequently, the models of AGB were highly accurate (R2 > 0.85, 0.90) for PAW and REB, respectively. Implications: To improve the estimates of AGB, we would not discount the future inclusion of more dasometric attributes, including spectral variables. It would also be advisable to refine these models by size and age ranges, as well as to apply other non-parametric statistical techniques. Conclusion: We argue that our methodology is useful for biomass estimation and acts to better facilitate the estimation of AGB compared to conventional techniques, as well as allowing subsequent calibration according to local conditions.
Actualización en Dermatología: Abordajes Clínicos y Terapéuticos en Patologías Cutáneas
Authors: Vélez Loor Kerly Germania , Jaramillo Saltos María Paz , Galarza Medina Patricia Noemí , Cueva Salan Andreina Ninoska , Vélez Marcel Lucy Priscila
Published: February 2025

La dermatología es una especialidad en constante evolución, con avances significativos en el diagnóstico y tratamiento de las enfermedades cutáneas. "Actualización en Dermatología: Abordajes Clínicos y Terapéuticos en Patologías Cutáneas" es una obra de referencia que reúne conocimientos actualizados y enfoques innovadores para el manejo de las patologías dermatológicas más relevantes en la práctica clínica
Differential gene expression analysis in patients with primary hyperhidrosis
Authors: Pu Ting , Jamal Muhammad Ameen , Tahir Muhammad Nauman , Ullah Salman , Awan Maher Un Nisa , Shahzad Asif , Mahmood Faisal
Published: February 2025

Hyperhidrosis, a condition of excessive sweat generation, is believed to be genetic, but it is yet not known well whether primary hyperhidrosis is regulated by a single gene or multiple genes. The prospective genes that regulate primary hyperhidrosis are known to be ITPR2, TMEM16A, FOXA1 and AQP5. Of these four genes, ITPR2 gene plays a significant role in primary hyperhidrosis; thus in the current research sequence, analysis of this gene was carried out. Following inclusion and exclusion criteria, whole blood samples were taken from four patients inflicted with primary hyperhidrosis and two from healthy persons as control. From the blood samples, white blood cells were separated by reacting the samples with ammonium chloride (NH4Cl) solution to lyse red blood cells. Then total RNA was extracted using the trizol reagent. For synthesizing cDNA, one script reverse transcriptase cDNA synthesis kit was employed. The cDNA samples were quantified using a Qubit Flourometer and their quality was appraised on agarose gel. Real time PCR was performed to carry out the quantitative analysis of these four genes. Of four genes, the expression of three genes, i.e., TMEM16A, ITPR2 and FOXA1, was found to be significantly high in the primary hyperhidrosis patients, whereas low expression of the gene AQP5 was noted compared to that of the control samples. Microarray data analysis on anhidrosis was done using GEO2R database as well as the anhidrosis datasets available on Gene Exression Omnibus (GEO). From this analysis, the low expression of FOXA1 in anhidrosis was confirmed. Based on the highest expression of ITPR2 in hyperhidrosis, it was selected for PCR amplification as well as sequencing. The sequence analysis of ITPR2 showed 100% identity without any mutation.These key genes will further help us to devise new treatment modalities.
Estrategias de enfermería basadas en la teoría de la adaptación para manejo efectivo del duelo
Authors: Medina Vera Diana Brigitte , Nagua Sihua Kerly Juleisy , Sotomayor Preciado Anita Maggie
Published: February 2025

El duelo es una respuesta emocional compleja ante la pérdida de un ser querido o una experiencia significativa, cuya intensidad varía. Durante la pandemia de COVID-19, las tasas de duelo complicado aumentaron debido al impacto emocional y las pérdidas masivas, el estudio aborda las estrategias de enfermería basadas en la teoría de la adaptación para el manejo del duelo. Su objetivo fue desarrollar estrategias de enfermería basadas en la teoría de la adaptación, dirigidas a fortalecer el afrontamiento al duelo en jóvenes y adultos mayores. Se utilizó un enfoque cuantitativo, con diseño descriptivo y corte transversal, con 110 participantes mayores de 14 años que han experimentado un duelo, empleando el Inventario Texas Revisado de Duelo y la escala Likert, clasificando al duelo como alto, medio o bajo, y diferenciando entre duelo complicado y resuelto. Los resultados mostraron que el duelo alto predomina un 76.4%, especialmente en adultos mayores, quienes presentan mayor dificultad para adaptarse emocionalmente debido a factores como la soledad y la pérdida de seres cercanos. El duelo complicado prevalece en un 53.64% de los casos, evidenciando la necesidad de intervenciones específicas. Las conclusiones resaltan la importancia de las estrategias de enfermería centradas en la adaptación emocional y el acompañamiento individualizado, estas intervenciones deben considerar las características sociodemográficas y emocionales de los dolientes, promoviendo un entorno de apoyo para procesar el duelo de manera saludable. Este enfoque integral busca no solo aliviar el dolor emocional, sino también prevenir complicaciones psicológicas asociadas al duelo complicado, fomentando una recuperación emocional adaptativa.
Prevención de caídas en pacientes hospitalizados: Revisión bibliográfica
Authors: Gordillo Carrión Ariana Belen , Macas Rogel Jamileth Samar , Quezada Honores Stefany Haylin , Vásquez Ruiz Kristhell Thaiz , Sotomayor Preciado Anita Maggie
Published: February 2025

Las caídas representan un problema de salud pública con consecuencias muy graves, tanto a nivel individual como para los sistemas de salud, debido al impacto que tienen en la calidad de vida y los costos asociados a su atención. El siguiente estudio tiene como objetivo analizar el cumplimiento del indicador de prácticas seguras en la prevención de caídas en pacientes hospitalizados mediante una revisión bibliográfica, con el propósito de contribuir al fortalecimiento de una atención hospitalaria segura y de calidad. La metodología aplicada fue de tipo descriptivo, basado en la búsqueda de artículos científicos actualizados en los últimos 5 años sobre la Prevención de caídas. Los resultados abarcan los conocimientos, factores intrínsecos y extrínsecos, valoración y notificación con relación a la temática. Además, contribuye a la reducción de la incidencia de caídas y sus consecuencias, mejorando la calidad de vida de las personas en estado de riesgo y optimizando los recursos del sistema sanitario. En conclusión, el conocimiento del personal de enfermería sobre los factores de riesgo asociados a las caídas y el manejo adecuado de herramientas de valoración revela su importancia en la prevención de eventos adversos dentro del entorno hospitalario.
Penerapan Manajemen Risiko Pada Destinasi Wisata Sungai Palayangan Cileunca, Kabupaten Bandung
Authors: Ariya Aurel Megantara  , Muhammad Faishal Rabbani Zahran
Published: February 2025

This research is to identify and evaluate risk management practices in tourist destinations in order to improve sustainability and tourist safety. The tourism industry is mandated to adopt risk management as it seeks to maintain the good reputation of the destination, increase tourist attraction, and instill confidence that tourists will return to the destination. This is being done. With the increasing number of tourists, environmental and health risks have become a major concern for the management of tourist destinations. This research methodology uses descriptive qualitative primary data obtained from direct field observations and interviews. Data was collected through in-depth interviews with destination managers, tourist surveys, and analysis of relevant policy documents. The findings show that there is systematic risk management in place, including identifying potential risks of accidents and environmental damage. The study shows that regular staffing and collaboration with local stakeholders are important for maintaining long-term sustainability. Effective risk management enables tourist destinations to provide safer and higher-quality experiences for tourists. Risk management practices implemented include pre-tour safety briefings, provision of life jackets, and cancellation of tours in case of heavy rain or wildlife presence. Management control initiatives already exist but have not been optimized.
Analisis Potensi Pengembangan Ekowisata Pantai Pondok Bali Desa Mayangan, Kecamatan Legonkulon, Kabupaten Subang
Authors: Lindiyani Lindiyani  , Tri Cahyanto
Published: February 2025

Pondok Bali Beach, which is located in a coastal area rich in natural and cultural beauty, has great potential for ecotourism development. This research aims to analyze the potential for ecotourism at Pondok Beach in Bali and identify sustainable development strategies. The methods used include field surveys, interviews with local communities, visitors and managers, as well as SWOT to understand the strengths, weaknesses, opportunities and threats in ecotourism development. The parameters measured in data collection are attractions, amenities, accessibility and community involvement. The analysis results show that Pondok Bali Beach has a great opportunity to be developed as an ecotourism destination. By considering the existing attractions, as well as adequate accessibility factors, amenities and attractions, coupled with the active participation of the local community, this potential can be maximized
Analisis Pengambilan Keputusan dalam Kendala di Wisata Alam Kaliwungu Karawang Jawa Barat
Authors: Delia Karya  , Khurfa Tusiva  , Muhammad Yusuf Hanifan  , Nazwa Putri Gunawan
Published: February 2025

Kaliwungu nature tourism in Karawang, West Java, faces various constraints in management that impact strategic decision making. This study aims to analyze the main constraints that include the management of labor, capital, raw materials, and marketing. The study used a qualitative approach with an explanatory survey method, where data were collected through interviews, observation, and document analysis. The results show that labor management faces challenges in the form of dependence on labor from outside the region, which causes high operational costs. Capital management also requires adjustments to the Break Even Point (BEP) time from three to four years due to low levels of tourist visits. In terms of raw materials, inventory shortages often occur, affecting visitor satisfaction. On the marketing side, the utilization of digital media has not been optimal to attract tourists from outside the region. Further discussion underscores the importance of more efficient management strategies, including the development of local labor, strengthening digital marketing, and better raw material management. The practical implications of this research include the need for innovation in marketing strategies, improved service quality, as well as more planned resource management to increase the competitiveness of Kaliwungu tourism in both local and national markets. The conclusion of this study provides important insights for tourism managers to optimize their decision making and operational sustainability.
Pengaruh Online Review terhadap Brand Image di UNP Hotel & Convention Center Padang
Authors: Nur Fadillah  , Violintikha Harmawan
Published: February 2025

The objective of this study is to analyze online reviews and brand image at Unp Hotel & Convention Center Padang. The study is motivated by the fact that UNP Hotel Convention has a considerable potential due to several factors that are exceptionally supportive for accommodation. The study uses quantitative methods and the type of research used in this study is associative causal or cause and effect relationships. The data obtained from survey results was separated into respondents who were the objects of research. The influence of the Online Review variable on Brand Image has a sample mean value of 0.744, a tstatistics value of 30.942> 1.96, and a p value of 0.000 <0.05. As a result, there is a positive and significant influence of the Online Review variable with Brand Image, so H1 is accepted.
The Impact of Destructive Fishing on the Development of Marine Tourism in Indonesia: A Case Study of Kapoposang Island, Pangkajene and Islands Regency, South Sulawesi Province, Indonesia
Authors: Andi Ajeng Lara Zary  , Agussalim Burhanuddin  , Seniwati Seniwati
Published: February 2025

As an archipelago, Indonesia has a vast ocean and is rich in biodiversity. With a vast ocean, Indonesia has considerable marine ecotourism potential. However, the problem that needs to be solved is destructive fishing in Indonesian waters. Destructive fishing can damage the marine ecosystem and reduce the number of marine life that characterizes Indonesian waters. Kapoposang Island is one of Indonesia's areas with great marine ecotourism potential. However, on Kapoposang Island, there are cases of destructive fishing which are feared to hurt the development of marine ecotourism. Besides that, community participation is needed so that an increase can follow the growth of marine ecotourism on Kapoposang Island in the standard of living of the local community, one of which is the economy. This study examined the relationship between destructive fishing and tourism development on Kapoposang Island. The research was conducted using a qualitative approach to analyze the impact of destructive fishing on the development of marine ecotourism on Kapoposang Island, Pangkajene Islands Regency, South Sulawesi. Researchers used data sources in the form of interviews and literature studies.
Pengaruh Model Paired Storytelling terhadap Keterampilan Berbicara pada Materi Menceritakan Kembali Isi Fabel di Kelas VII SMP Negeri 1 Tigabinanga
Authors: Juli Laurensia Br Ginting  , Rosmaini Rosmaini
Published: February 2025

This research is motivated by the low speaking skills of students in retelling fable texts which are influenced by several factors. This study aims to determine the effect of the paired storytelling learning model on students' speaking skills in retelling fables in class VII of SMP Negeri 1 Tigabinanga. The method used in this study is an experimental method with a two-group posttest only design. The population in this study were all students of class VII of SMP Negeri 1 Tigabinanga totaling 210 people and the sample of this study was students of class VII 3 experimental class with a total of 31 students and VII 4 as a control class with a total of 30 students. The data analysis technique used in this study is quantitative data by testing the analysis requirements, homogeneity test, homogeneity, and hypothesis test. The results of the study in the experimental class obtained an average value of 82.90 in the good category, while the results of the study in the control class at an average value of 53.50 were in the very poor category. Based on the test of equality of average values, it is known that the experimental class has a higher value than the control class with a difference of 29.4%. Based on the t-test that has been carried out, the value at the significance level α = 0.05 is obtained, the value of the t-table provision is 1.67109 and the result of t count = 10.8110. Then the hypothesis t-test> t-test, namely 10.8110> 1.67109, so that the null hypothesis (Ho) is rejected and the alternative hypothesis (Ha) is accepted. In terms of consistency, it can be concluded that learning by using the paired storytelling model has a positive and significant effect on the skills of telling the contents of fable texts of class VII students of SMP Negeri 1 Tigabinanga.
Pengaruh Pengunaan Media Audiovisual oleh Guru PAK terhadap Minat Belajar Siswa Kelas VIII SMP Negeri 1 Sianjur Mula-Mula Kabupaten Samosir Tahun Pembelajaran 2023/2024
Authors: Selvia Novalina Marpaung  , Frainskoy Rio Naibaho  , Hisardo Sitorus  , Raikhapoor Raikhapoor  , Lince R.T Simamora
Published: February 2025

The research aims to determine the effect of the use of audiovisual media by PAK teachers on the learning interest of class VIII students at SMP Negeri 1 Sianjur Mula at Samosir Regency for the 2023/2024 academic year. The research hypothesis is that there is a positive and significant influence between the use of audiovisual media by PAK teachers on the learning interest of class VIII students at SMP Negeri 1 Sianjur Mula at Samosir Regency for the 2023/2024 academic year. Descriptive and inferential quantitative research methods. The population of all class VIII students at SMP Negeri 1 Sianjur Initially in Samosir Regency for the 2023/2024 academic year who are Protestant Christians is 123 people. The sample was random (random sampling), namely 50% of the total population, namely 62 people. The research instrument is a closed questionnaire. The results of data analysis obtained: a) The value of rcount=0.576> rtable=0.254 and tcount=5.458> ttable=2.00030 shows that there is a positive and significant relationship between the use of audiovisual media by PAK teachers and the learning interest of class VIII students at SMP Negeri 1 Sianjur Mula -starting with Samosir Regency for the 2023/2024 Academic Year. b) Regression equation. c) The determination test revealed that the magnitude of the effect was 33.18%. d) Hypothesis testing obtained Fcount=28.971>Ftable=3.15 then H0 (null hypothesis) is rejected and Ha (alternative hypothesis) is accepted. The research concluded that there was a positive and significant influence between the use of audiovisual media by PAK teachers on the learning interest of class VIII students at SMP Negeri 1 Sianjur Mula at Samosir Regency for the 2023/2024 academic year.
Analisis Kajian Stuktural Pada Cerpen “Kembang Mayang” Karya Titie Said
Authors: Mirabella Husen Asgaf  , Lusi Nur Triani
Published: February 2025

The short story Kembang Mayang has a theme centered around women's emancipation. It follows a forward plot, although there is a brief flashback in the middle of the story. However, the flashback does not affect the overall storyline; it merely strengthens it. The main character in Kembang Mayang is Eka. The characters of Eka’s mother, father, Mulyo, and his seven younger siblings are secondary characters who primarily serve as supporting elements to the story. Eka is portrayed as a tough, responsible, and loving individual. The story takes place in the early morning before dawn in a house in Ciganjur. The author uses the third-person point of view, not using the pronoun "I," but instead referring to the main character by name. The short story employs a direct and simple language style, though it is occasionally interspersed with certain metaphors. Despite this, the style remains straightforward and clear.
Peradaban Islam pada Masa Khalifah Abu Bakar Ash-Shiddiq
Authors: Tasya Aryati Sakinah  , Wafiq Zahira Mardatilah  , Sania Junila
Published: February 2025

Islamic civilization during the time of Abu Bakar As-Siddiq was a period that played a key role in the early development of Islam. Abu Bakr, who was the closest friend of the Prophet Muhammad SAW, was the first Caliph of Muslims after the death of the Prophet. This journal explains Abu's role Burn in building Islamic civilization, which includes the spread of religion, collecting the Koran, financial and social policies, as well as an emphasis on justice and law. His leadership wisdom and the Islamic principles he implemented have helped form the basis for strong and sustainable Islamic civilization. This period plays an important role in determine the future of Islam and provides inspiration for the next generation to live a life in accordance with the noble values ​​of Islam.
Pelestarian Budaya Melayu dalam Filosofi Rumah Lontiok Melalui Eksplorasi Budaya di Desa Pulau Belimbing
Authors: Siti Nila Lestari  , Suci Aulia Sya'ban  , Nailaturrahmah Insani  , Rahmi Fadillah  , Putri Salisa  , Elmustian Elmustian
Published: February 2025

The preservation of Malay culture, particularly through the philosophy of the Lontiok house, plays a significant role in maintaining the cultural identity and traditional values of the community. The Lontiok house, as a symbol of Malay culture, serves not only as a dwelling but also reflects the community's close relationship with nature and spirituality. This study aims to explore how the philosophy of the Lontiok house is preserved in Pulau Belimbing Village through the cultural practices in the local community. The research employs a qualitative approach, focusing on an in-depth understanding of the cultural phenomena that exist in the village. Data were gathered through direct observation, interviews with local residents, and relevant literature review. The findings show that the preservation of the Lontiok house in Pulau Belimbing Village is carried out not only through the construction and maintenance of the traditional house but also through cultural education, traditional ceremonies, and the development of culture-based tourism. The study also reveals that the community plays an active role in preserving and passing on the philosophy contained in the Lontiok house to the younger generation, ensuring the continuity of Malay cultural heritage. It is hoped that the results of this study can contribute to the future preservation of Malay culture and introduce the uniqueness of local culture to the outside world.