bluuebunny/crossref_metadata_2025 huggingface dataset:
FLT3 inhibitors as MRD-guided salvage treatment for molecular failure in FLT3 mutated AML
Authors: Othman Jad , Potter Nicola , Mokretar Katya , Taussig David , Khan Anjum , Krishnamurthy Pramila , Latif Anne-Louise , Cahalin Paul , Aries James , Amer Mariam , Belsham Edward , Conneally Eibhlin , Craddock Charles , Culligan Dominic , Dennis Mike , Duncan Caroline , Freeman Sylvie D. , Furness Caroline , Gilkes Amanda , Gkreka Paraskevi , Hodgson Katherine , Ingram Wendy , Jain Manish , King Andrew , Knapper Steven , Kottaridis Panagiotis , McMullin Mary Frances , Mohite Unmesh , Ngu Loretta , O’Nions Jenny , Patrick Katharine , Rider Tom , Roberts Wing , Severinsen Marianne Tang , Storrar Neill , Taylor Tom , Russell Nigel H. , Dillon Richard
Published: August 2023

Patients with FLT3-mutated AML have a high relapse rate and suboptimal outcomes. Many have co-mutations suitable for measurable residual disease (MRD) monitoring by RT-qPCR and those destined to relapse can be identified by high or rising levels of MRD, called molecular failure.  This provides a window for pre-emptive intervention, but there is little evidence to guide treatment. The use of FLT3 inhibitors (FLT3i) appears attractive but their use has not yet been evaluated.  We identified 56 patients treated with FLT3i at molecular failure.  The FLT3 mutation was an ITD in 52, TKD in 7 and both in 3. Over half of patients had previously received midostaurin. Molecular failure occurred at a median 9.2 months from diagnosis and was treated with gilteritinib (n = 38), quizartinib (n = 7) or sorafenib (n = 11). 60% achieved a molecular response, with 45% reaching MRD negativity. Haematological toxicity was low, and 22 patients were bridged directly to allogeneic transplant with another 6 to donor lymphocyte infusion. 2-year overall survival was 80% (95%CI 69–93) and molecular event-free survival 56% (95%CI 44–72). High-sensitivity next-generation sequencing for FLT3-ITD at molecular failure identified patients more likely to benefit. FLT3i monotherapy for molecular failure is a promising strategy which merits evaluation in prospective studies.
Self-sensing intelligent microrobots for noninvasive and wireless monitoring systems
Authors: Li Zhongyi , Wang Kun , Hou Chaojian , Li Chunyang , Zhang Fanqing , Ren Wu , Dong Lixin , Zhao Jing
Published: August 2023

Microrobots have garnered tremendous attention due to their small size, flexible movement, and potential for various in situ treatments. However, functional modification of microrobots has become crucial for their interaction with the environment, except for precise motion control. Here, a novel artificial intelligence (AI) microrobot is designed that can respond to changes in the external environment without an onboard energy supply and transmit signals wirelessly in real time. The AI microrobot can cooperate with external electromagnetic imaging equipment and enhance the local radiofrequency (RF) magnetic field to achieve a large penetration sensing depth and a high spatial resolution. The working ranges are determined by the structure of the sensor circuit, and the corresponding enhancement effect can be modulated by the conductivity and permittivity of the surrounding environment, reaching ~560 times at most. Under the control of an external magnetic field, the magnetic tail can actuate the microrobotic agent to move accurately, with great potential to realize in situ monitoring in different places in the human body, almost noninvasively, especially around potential diseases, which is of great significance for early disease discovery and accurate diagnosis. In addition, the compatible fabrication process can produce swarms of functional microrobots. The findings highlight the feasibility of the self-sensing AI microrobots for the development of in situ diagnosis or even treatment according to sensing signals.
Aggregation algorithm based on consensus verification
Authors: Shichao Li , Jiwei Qin
Published: August 2023

Distributed learning, as the most popular solution for training large-scale data for deep learning, consists of multiple participants collaborating on data training tasks. However, the malicious behavior of some during the training process, like Byzantine participants who would interrupt or control the learning process, will trigger the crisis of data security. Although recent existing defense mechanisms use the variability of Byzantine node gradients to clear Byzantine values, it is still unable to identify and then clear the delicate disturbance/attack. To address this critical issue, we propose an algorithm named consensus aggregation in this paper. This algorithm allows computational nodes to use the information of verification nodes to verify the effectiveness of the gradient in the perturbation attack, reaching a consensus based on the effective verification of the gradient. Then the server node uses the gradient as the valid gradient for gradient aggregation calculation through the consensus reached by other computing nodes. On the MNIST and CIFAR10 datasets, when faced with Drift attacks, the proposed algorithm outperforms common existing aggregation algorithms (Krum, Trimmed Mean, Bulyan), with accuracies of 93.3%, 94.06% (MNIST dataset), and 48.66%, 51.55% (CIFAR10 dataset), respectively. This is an improvement of 3.0%, 3.8% (MNIST dataset), and 19.0%, 26.1% (CIFAR10 dataset) over the current state-of-the-art methods, and successfully defended against other attack methods.
CUI-Net: a correcting uneven illumination net for low-light image enhancement
Authors: Chao Ke , Song Wei , Shao Sen , Liu Dan , Liu Xiangchun , Zhao XiaoBing
Published: August 2023

Uneven lighting conditions often occur during real-life photography, such as images taken at night that may have both low-light dark areas and high-light overexposed areas. Traditional algorithms for enhancing low-light areas also increase the brightness of overexposed areas, affecting the overall visual effect of the image. Therefore, it is important to achieve differentiated enhancement of low-light and high-light areas. In this paper, we propose a network called correcting uneven illumination network (CUI-Net) with sparse attention transformer and convolutional neural network (CNN) to better extract low-light features by constraining high-light features. Specifically, CUI-Net consists of two main modules: a low-light enhancement module and an auxiliary module. The enhancement module is a hybrid network that combines the advantages of CNN and Transformer network, which can alleviate uneven lighting problems and enhance local details better. The auxiliary module is used to converge the enhancement results of multiple enhancement modules during the training phase, so that only one enhancement module is needed during the testing phase to speed up inference. Furthermore, zero-shot learning is used in this paper to adapt to complex uneven lighting environments without requiring paired or unpaired training data. Finally, to validate the effectiveness of the algorithm, we tested it on multiple datasets of different types, and the algorithm showed stable performance, demonstrating its good robustness. Additionally, by applying this algorithm to practical visual tasks such as object detection, face detection, and semantic segmentation, and comparing it with other state-of-the-art low-light image enhancement algorithms, we have demonstrated its practicality and advantages.
Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population
Authors: Simonyte Sandrita , Grabauskyte Ingrida , Macijauskiene Jurate , Lesauskaite Vita , Lesauskaite Vaiva , Kvaal Kari Sofie , Stewart Robert
Published: August 2023

Late-life depression (LLD) is a multifactorial disorder, with susceptibility and vulnerability potentially influenced by gene-environment interaction. The aim of this study was to investigate whether the 5-HTTLPR polymorphism is associated with LLD. The sample of 353 participants aged 65 years and over was randomly selected from the list of Kaunas city inhabitants by Residents’ Register Service of Lithuania. Depressive symptoms were ascertained using the EURO-D scale. The List of Threatening Events Questionnaire was used to identify stressful life events that happened over the last 6 months and during lifetime. A 5-HTTLPR and lifetime stressful events interaction was indicated by higher odds of depression in those with s/s genotype who experienced high stress compared to l/l carriers with low or medium stress, while 5-HTTLPR and current stressful events interaction analysis revealed that carriers of either one or two copies of the s allele had increased odds of depressive symptoms associated with stress compared to participants with the l/l genotype not exposed to stressful situations. Although no significant direct association was found between the 5-HTTLPR short allele and depression, our findings demonstrated that lifetime or current stressful life events and their modification by 5-HTTLPR genotype are risk factors for late-life depression.
Phase vortex lattices in neutron interferometry
Authors: Geerits Niels , Lemmel Hartmut , Berger Anna-Sophie , Sponar Stephan
Published: August 2023

Neutron Orbital Angular Momentum (OAM) is an additional quantum mechanical degree of freedom, useful in quantum information, and may provide more complete information on the neutron scattering amplitude of nuclei. Various methods for producing OAM in neutrons have been discussed. In this work we generalize magnetic methods which employ coherent averaging and apply this to neutron interferometry. Two aluminium prisms are inserted into a nested loop interferometer to generate a phase vortex lattice with significant extrinsic OAM, 〈Lz〉 ≈ 0.35, on a length scale of ≈ 220 μm, transverse to the propagation direction. Our generalized method exploits the strong nuclear interaction, enabling a tighter lattice. Combined with recent advances in neutron compound optics and split crystal interferometry our method may be applied to generate intrinsic neutron OAM states. Finally, we assert that, in its current state, our setup is directly applicable to anisotropic ultra small angle neutron scattering.
Revisiting the electronic structure of N2-bound cAAC-borylene at the CASSCF level: a detailed bonding picture of borylene–N2 interaction
Authors: Ghosh Susovon , Bhardwaj Akhil , Mondal Bhaskar
Published: August 2023

A detailed synergistic bonding picture between cAAC-stabilised borylene and N2 has been established through orbitals derived from multiconfigurational CASSCF calculations accounting for the non-dynamic electron correlation.
Highly efficient green-emitting ZnO:Cu2+ phosphors for NUV-pumped white-emitting diodes
Authors: Tran Manh Trung , Quang Trung Do , Tri Tuan Nguyen , Tuan Nguyen Trong , Tu Nguyen , Van Du Nguyen , Duy Hung Nguyen , Van Quang Nguyen , Thi Hao Tam Tong , Trung Kien Nguyen Duc , Hieu Nguyen Minh , Huy Pham Thanh
Published: August 2023

A WLED prototype obtained by applying efficient green ZnO:Cu2+ phosphors, made via thermal diffusion, onto near-ultraviolet light source.
Intraparticle ripening to create hierarchically porous Ti-MOF single crystals for deep oxidative desulfurization
Authors: Yu Shen , Liu Zhan , Lyu Jia-Min , Guo Chun-Mu , Wang Yi-Long , Hu Zhi-Yi , Li Yu , Sun Ming-Hui , Chen Li-Hua , Su Bao-Lian
Published: August 2023

For the first time, Ti-MOF single crystals featuring an intracrystal meso–microporous hierarchy were prepared by a facile method of intraparticle ripening, and excellent deep catalytic oxidative desulfurization performance was achieved.
Recent progress in structural modification of polymer gel electrolytes for use in solid-state zinc-ion batteries
Authors: Li Yifan , Yuan Jingjing , Qiao Yifan , Xu Hui , Zhang Zhihao , Zhang Wenyao , He Guangyu , Chen Haiqun
Published: August 2023

The main categories of additives used to improve the electrochemical properties of solid gel electrolytes and obtain other excellent performances in zinc ion batteries.
Synthesis and reactivity of alkali metal aluminates bearing bis(organoamido)phosphane ligand
Authors: Vrána Jan , Růžičková Zdeňka , Růžička Aleš , Dostál Libor
Published: August 2023

In this study, we report a group of alkali metal aluminates bearing bis(organoamido)phosphane ligand.
An efficient LiSrGaF6:Cr3+ fluoride phosphor with broadband NIR emission towards sunlight-like full-spectrum lighting
Authors: Wu Di , Li Yan , Liao Yu , Pan Xixiang , Liu Songbin , Zou Wanfang , Peng Jiaqing , Ye Xinyu
Published: August 2023

A highly continuous sunlight-like pc-LED was fabricated by employing a novel LiSrGaF6:Cr3+ NIR phosphor with a high-efficiency and thermally stable broadband NIR emission.
Generation of Ru(iii)-hypochlorite with resemblance to the heme-dependent haloperoxidase enzyme
Authors: Kumar Rakesh , Ahsan Faiza , Awasthi Ayushi , Swart Marcel , Draksharapu Apparao
Published: August 2023

The reaction of (Me/BnTPEN)RuII with mCPBA in the presence of Cl− ions generated a novel (Me/BnTPEN)RuIII–OCl species at RT. This study mimics the synthesis of a MIII–OCl adduct in a similar fashion as in the heme dependent haloperoxidase enzyme.
Trinitromethyl-triazolone (TNMTO): a highly dense oxidizer
Authors: Lal Sohan , Staples Richard J. , Shreeve Jean'ne M.
Published: August 2023

A scalable synthesis of 5-(trinitromethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (TNMTO) is possible from commercially available 2-methylpyrimidine-4,6-diol.
Case study evaluation of size-resolved molecular composition and phase state of carbonaceous particles in wildfire influenced smoke from the Pacific Northwest
Authors: Vandergrift Gregory W. , Lata Nurun Nahar , Mathai Susan , Ijaz Amna , Cheng Zezhen , Shrivastava Manish , Zhang Jie , Md Shawon Abu Sayeed , Kulkarni Gourihar , Mazzoleni Lynn R. , Kew William , China Swarup
Published: August 2023

Wildfires are significant sources of carbonaceous particles in the atmosphere.
Physical modification of hydroxyapatite: the drastic enhancement of both cation (Cd2+) and anion (F−) adsorption and recycling efficiency
Authors: Eswaran Panchu Sandeep , Sekar Saranya , Kolanthai Elayaraja , Gandhi Mano Balaji , Babu Sridharan Moorthy , Kalkura Subbaraya Narayana
Published: August 2023

(1) Novel physically modified (by ultrasound and freeze-drying) HAp nanoparticles (2) drastic enhancement in the Cd2+ (208%) and F− (488%) adsorption capacities along with rapid adsorption and greater recycling efficiency compared to the reported data.
An iron “nano-fishnet” for the rapid removal and surface clean-up of micro/nanoplastics from seawater
Authors: Zhang Yufei , Dong Zhiqiang , Deng Zilong , Shi Shuaiyi , Tang Chenliu , Hu Xiang
Published: August 2023

A magnetic iron “nano-fishnet” (i.e., alkylated nanoscale zerovalent iron grown on naturally derived cellulose nanofibers (ac-nZVI)) was fabricated for the rapid removal and surface clean-up of micro/nanoplastics from seawater.
A UV solar-blind nonlinear optical crystal with confined π-conjugated groups
Authors: Song Xianyu , Du Zhipeng , Ahmed Belal , Li Yanqiang , Zhou Yang , Song Yipeng , Huang Weiqi , Zheng Jieyu , Luo Junhua , Zhao Sangen
Published: August 2023

The confined π-conjugated groups [PO2(NH)3(CO)2] help to achieve a good balance of SHG, bandgap, and birefringence.
Polycystic kidneys: interaction of notch and renin
Authors: Daniel Emily A. , Sommer Nicole A. , Sharma Madhulika
Published: August 2023

Polycystic kidney disease (PKD) is a developmental disorder, which either manifests in early childhood or later in life, depending on the genetic mutation one harbors. The mechanisms of cyst initiation are not well understood. Increasing literature is now suggesting that Notch signaling may play a critical role in PKD. Activation of Notch signaling is important during nephrogenesis and slows down after development. Deletion of various Notch molecules in the cap mesenchyme leads to formation of cysts and early death in mice. A new study by Belyea et al. has now found that cells of renin lineage may link Notch expression and cystic kidney disease. Here, we use our understanding of Notch signaling and PKD to speculate about the significance of these interactions.
Wav2DDK: Analytical and Clinical Validation of an Automated Diadochokinetic Rate Estimation Algorithm on Remotely Collected Speech
Authors: Kadambi Prad , Stegmann Gabriela M. , Liss Julie , Berisha Visar , Hahn Shira
Published: August 2023

Purpose:

Oral diadochokinesis is a useful task in assessment of speech motor function in the context of neurological disease. Remote collection of speech tasks provides a convenient alternative to in-clinic visits, but scoring these assessments can be a laborious process for clinicians. This work describes Wav2DDK, an automated algorithm for estimating the diadochokinetic (DDK) rate on remotely collected audio from healthy participants and participants with amyotrophic lateral sclerosis (ALS).

Method:

Wav2DDK was developed using a corpus of 970 DDK assessments from healthy and ALS speakers where ground truth DDK rates were provided manually by trained annotators. The clinical utility of the algorithm was demonstrated on a corpus of 7,919 assessments collected longitudinally from 26 healthy controls and 82 ALS speakers. Corpora were collected via the participants' own mobile device, and instructions for speech elicitation were provided via a mobile app. DDK rate was estimated by parsing the character transcript from a deep neural network transformer acoustic model trained on healthy and ALS speech.

Results:

Algorithm estimated DDK rates are highly accurate, achieving .98 correlation with manual annotation, and an average error of only 0.071 syllables per second. The rate exactly matched ground truth for 83% of files and was within 0.5 syllables per second for 95% of files. Estimated rates achieve a high test-retest reliability (
r
= .95) and show good correlation with the revised ALS functional rating scale speech subscore (
r
= .67).

Conclusion:

We demonstrate a system for automated DDK estimation that increases efficiency of calculation beyond manual annotation. Thorough analytical and clinical validation demonstrates that the algorithm is not only highly accurate, but also provides a convenient, clinically relevant metric for tracking longitudinal decline in ALS, serving to promote participation and diversity of participants in clinical research.

Supplemental Material:

https://doi.org/10.23641/asha.23787033
A novel approach to battery cell balancing using near‐field wireless power transfer
Authors: Jeon Juhyeon , Seo Sangsoo , Han Sangwook , Lee Dongho
Published: August 2023

This paper presents a novel battery cell balancing technique using near‐field wireless power transfer (WPT). The proposed method aims to overcome the drawbacks of conventional passive methods, which have low efficiency and energy waste, as well as the complex control and slow balancing speed of active methods. The authors’ experiments demonstrate, for the first time, the successful application of near‐field WPT for cell balancing. By wirelessly replenishing energy to the low‐energy battery cells while simultaneously charging them via wired connections, the authors achieve a significant reduction of 55.7% in the cell balancing time compared to conventional methods. The effectiveness of the proposed technique is validated through experimental results. This approach offers a promising solution for efficient and fast cell balancing in battery systems.
An improved subdomain method for air gap flux density of interior permanent magnet machines based on rotor reconstruction and flux equivalence
Authors: Wu Pengfei , Sun Yanhua
Published: August 2023

The aim of this article is to develop a rotor reconstruction method for the V‐shaped interior permanent magnet (IPM) machine so that the subdomain method to analytically calculate the air‐gap flux density can be applied. With the proposed method, the V‐shaped IPM rotor with rectangular magnets, magnetic barriers, and saturated iron bridges can be transformed into a U‐shaped equivalent analytical model. The geometry and material parameters of the magnets in the equivalent U‐shaped model can be determined according to the flux equivalence in the air‐gap of the motor. Then using the subdomain method on the U‐shaped equivalent rotor, the static magnetic field problem can be solved and the flux density distribution in the air‐gap be obtained. The validity of this method and accuracy of the solution is verified by the finite element method with case studies. Compared with existing methods, the improved subdomain method has higher accuracy in calculating flux density including radial and tangential components. The presented rotor reconstruction method is not only limited to single‐layer V‐shaped rotor, it can also be applied to other IPM rotors with more complex structures. It is valuable in the design, optimisation of IPM motors, and even development of new rotor topology.
Modelling spatiotemporal impact of flash floods on power distribution system and dynamic service restoration with renewable generators considering interdependent critical loads
Authors: Afzal Suhail , Mokhlis Hazlie , Illias Hazlee Azil , Bajwa Abdullah Akram , Mekhilef Saad , Mubin Marizan , Muhammad Munir Azam , Shareef Hussain
Published: August 2023

In recent decades, flash floods have become more common because of climate change and are considered a substantial risk for many cities worldwide. This catastrophic natural hazard presents a significant threat to critical infrastructure in urban areas, particularly the power distribution system. As modern societies are much more dependent on electrical energy these days, it is essential and imperative to make existing distribution systems resilient against flash flooding. Although researchers in this area have proposed various algorithms to impart resilience to a distribution system, however, the focus in these works is on wind‐related events such as hurricanes, cyclones, and windstorms. Therefore, here, the spatiotemporal effects of a flash flood on the distribution system are modelled using a grid‐based hydrodynamic model. The evolving line faults are then included in the proposed resilience‐oriented time horizon‐based service restoration model that also considers dynamic load demand, heavy uncertainties related to renewable generation, and interdependence among critical loads. Finally, the resilience of the distribution system's response is assessed using an operational resilience metric. The efficacy of the proposed framework is evaluated on IEEE 33‐bus and 69‐bus systems and the results show that the model provides an efficient restoration solution despite increased complexity caused by varying conditions.
Multi‐time scale adequacy evaluation of the power system with high penetration of renewable energy sources based on empirical mode decomposition
Authors: Zhang Wenbo , Xing Haijun , Sun Yiwen , Huang Ruanming , Song Ziyu , Luo Jiayi , Bian Xiaoyan
Published: August 2023

Adequacy, especially in the power system with high penetration of renewable energy sources, is a crucial consideration in power system planning and operational dispatching. A multi‐time scale adequacy evaluation method based on empirical mode decomposition (EMD) is proposed, taking into account the multi‐time scale characteristics of renewable energy sources and the response characteristics of flexible regulation resources. In this method, a net load curve is decomposed into several component curves by the EMD algorithm. Then, the adequacy demand on each time scale is obtained by waveform recognition. Furthermore, the available adequacy resources on different time scales are quantified according to the regulation models of flexible resources. By analysing the adequacy demand and available adequacy resources of the power system on the same time scale, the adequacy evaluation indices on each time scale can be calculated and weighted to form the comprehensive indices. Finally, the adequacy evaluation indices on each time scale with different capacities of renewable energy sources and energy storage systems are compared and analysed using a practical power system as a case. Simulation results show the validity of the multi‐time scale adequacy evaluation method.
Electromagnetic disturbance characteristic of typical high voltage switchgear interruption process in offshore wind farm based on integrated conduction model
Authors: Wang Huaqing , Huang Daochun , Shuang Mingjing , Li Huipeng , Qiu Yiqun
Published: August 2023

In an offshore wind farm, a high‐voltage switchgear interruption in an offshore substation creates a high‐frequency, high‐amplitude overvoltage that can cause severe electromagnetic interference problems in the intelligent electronic device. To address this issue, mathematical models, vector fitting and finite element method were used to build an integrated electromagnetic disturbance conduction model, whose accuracy was verified by large current interruption tests. Through the simulation of a typical offshore wind farm's single‐phase grounding fault interruption process, the electromagnetic disturbance characteristics and the impact of the ground position are obtained. The results show that during the fault interruption process of phase B grounded, the dominant frequency of disturbance voltage can reach 4.34 MHz, and the amplitude can reach 1.12 kV. The ground grid has a large impact on the interference voltage, which can reach a maximum value of 2.28 kV under specific conditions. The disturbance voltage in the fault process mainly comes through the current transformer, while during the interruption process, it mainly comes through the ground grid. The authors provide a method to establish the integrated electromagnetic disturbance simulation model, which can improve the accuracy of the electromagnetic disturbance conduction process simulation of intelligent components.
Influence of mineral additives on the rheological and strength properties of fine-grained concrete
Authors: Puzatova Anastasiia , Kogai Alina , Dmitrieva Maria
Published: August 2023

The paper considers 4 types of mineral additives for concrete - metakaolin, silica fume, wollastonite and zeolite - and their influence on the rheological properties and strength of fine-grained concrete, in which part of the cement is replaced by a mineral additive. It is shown that the replacement of 5-10% of cement with active mineral additives with a specific surface area 1.5 times or more greater than the specific surface area of cement (metakaolin, silica fume) leads to a decrease in the flowability of the mixture in proportion to the increase in the amount of additive in the system. When replacing 10% of cement with additives, the specific surface of which relative to cement is in the range of 0.88-1.2 (wollastonite, zeolite), on the contrary, increases the flowability of the mixture. The strength of all samples with mineral additives at 28 days of age was greater than that of the control composition. An increase in strength by 1.7-1.76 times is noted for compositions with the replacement of 10% cement with metakaolin, wollastonite or zeolite.
Modified concrete for irrigation and drainage construction
Authors: Tkach Evgeniya , Filimonova Yulia
Published: August 2023

Within the framework of these studies, issues related to the modification of the composition of heavy concrete based on a polydisperse binder with a complex modifier and its influence on the formation of the structure and properties of cement stone, as well as hardened concrete, are considered. The purpose of the study is to substantiate the possibility of obtaining effective heavy concrete for irrigation and drainage construction with improved indicators of operational properties in terms of strength and hydrophysical characteristics. Object of study: heavy concrete based on a polydisperse binder with a complex modifier reinforced with basalt fiber. Subject of study: the structure and properties of heavy concrete based on a polydisperse cement binder with a high packing density together with a complex modifier and reinforced basalt fiber. The influence of the three-level dispersed composition of the clinker component of cement particles on the reduction of interparticle voidness and the increase in the strength of the cement stone was studied. The resulting modified concrete is characterized by an increase in strength to 77.3 MPa, a stretching of 8.62 MPa and a decrease in water absorption to 1.9%; % in comparison with the control composition.
Effect of mixture flowability on strength and fiber distribution of Ultra High-Performance Fiber Reinforced Concrete
Authors: Soloviev Vadim , Matiushin Evgenii , Mihailov Vladislav , Efishov Luka
Published: August 2023

The uniformity of distribution and the orientation factor of steel fibers are crucial parameters that determine the strength and uniformity of properties of Ultra High-Performance Fiber Reinforced Concrete (UHPFRC). The paper considers the influence of flowability and the method of casting the concrete mixture on the strength and fracture energy in bending of UHPFRC. The flowability was determined by the spread diameter of the mixture from the Hägermann cone, which was 270, 300, and 350 mm. It was found that the compressive strength of UHPFRC increases from 142 to 155 MPa with an increase in the mixture spread diameter. The strength and fracture energy in bending of UHPFRC near the ends of the mold are on average 14.5 and 17.7% less than in the central part. A relationship has been established between the flexural strength of UHPFRC and the fracture energy as a function of the relative area of the fiber in the cross-section. The optimal flowability range of UHPFRC (270…290 mm) was established analytically and experimentally, in which there is no critical decrease in strength properties and the ability of the mixture to self-leveling is maintained. Negative effects were established when changing flowability, outside the specified range.
Stabilized clay-gypsum binder
Authors: Asamatdinov M.O. , Caddo M.B. , Pilipenko A.S. , Sattorov S.M.
Published: August 2023

Clay gypsum is a natural sedimentary rock of chemical origin, containing from 50 to 95% of fine-grained crystalline gypsum, evenly distributed between clay minerals. The purpose of the research was to develop the compositions of the stabilized clay-gypsum binder, taking into account the temperature regimes of its firing. The studies were based on mathematical planning of the experiment with subsequent statistical processing of the results and obtaining polynomials that adequately describe the phenomena under study and with analytical optimization of these polynomials. It has been established that the optimal firing temperature of the initial sedimentary rock is 294–295 °C. The strength of the clay-gypsum binder is 8.8–8.6 MPa, which corresponds to the G-8 grade gypsum binder. The introduction of a superplasticizer additive makes it possible to increase the strength of the binder by 10–20%. As a result of the research, the technological parameters for obtaining a clay-gypsum binder, the modes of its heat treatment (roasting) were optimized, and the influence of technologies on the properties of the clay-gypsum binder, which can be considered as an analogue of a binder obtained from natural gypsum raw materials, was studied.
Procedure for determination of filtration coefficient of sheet piling fences from composite profiles
Authors: Medyankin Mikhail , Mikhaldykin Evgeniy
Published: August 2023

When designing structures made of sheet piles, it is often necessary to evaluate their filtration characteristics. The base material of the tongue is waterproof, however, groundwater filtration is carried out through special lock joints. The publication considers the procedure for experimental determination of the filtration coefficient of locking joints of sheet-pile fences made of polymer composite profiles based on the results of laboratory tests. Considering the mathematical model of filtration processes, it is based on a modified empirical Forchheimer dependence generalizing nonlinear filtration laws. The diagram of the test unit is given in the work. Using a specially developed method, the values of filtration coefficients at different pressure gradient values were obtained. It was found that when the sealing material is integrated into the locking joint zone, it is possible to achieve the value of the sheet-pile guard filtration coefficient of less than 10-10 m/s. The obtained results are of interest for solving the problems of the device of anti-filtration curtains with the use of composite sheet piles.
On the structure of cement stone with fillers from metallurgical waste
Authors: Adilkhodjaev Anvar , Kadyrov Ilkhom , Kudratov Bekzod , Azimov Doniyor , Xasanov Bahriddin , Umarov Isomiddin
Published: August 2023

The results of studies of the grinding of metallurgical slags in ball mills and data on the optimization of the grinding process are presented. The results of studies of the influence of the dispersion of the filler and the degree of filling on the formation of the strength of the cement stone are presented.
Centrifugal concrete poles for transmission lines reinforced with prestressed FRP rebar
Authors: Kudyakov Konstantin , Buchkin Andrey
Published: August 2023

Reinforced with steel rebar concrete centrifuged conical poles for power transmission poles receive corrosion damage to steel reinforcement during operation. These damages can lead to the failure of structures. Complete replacement of both longitudinal and transverse steel reinforcement by composite one is a way to increase the reliability and durability of such structures. This method also allows the use of cost-effective concretes with a low cement content. The research results have shown the viability of such solutions, but the use of composite reinforcement requires its prestressing. This article discusses the Russian practice of testing concrete centrifuged conical poles for strength, crack resistance and rigidity. A brief description of the prototypes and methods of their testing is given. The main results of bending tests of full-scale test samples are presented in the form of diagrams of their deformation. Analysis of the results showed that the test samples of poles are correspond to requirements of Russian norms for deformability, crack resistance and strength. According to the results the studied centrifugal concrete poles with prestressed longitudinal GFRP rebars and transverse spiral GFRP rebars are like traditional ones with steel reinforcement (in standardized strength, crack resistance and deflection values) and, therefore, can be used in building construction.
Torsion RC structures of asymmetric multistory buildings
Authors: Lyublinskiy Valery , Struchkov Vladislav
Published: August 2023

In multi-storey buildings that are asymmetrical in plan, an eccentricity occurs between the center of mass and the center of stiffness. Under the action of wind and seismic horizontal loads, torsion appears in the bearing system of the building. Torsion can also occur in nominally symmetrical buildings caused by uneven deformations of structural components. There are numerous analytical and experimental studies of the effect of torsion on bearing structures. It is required to assess the achievement of the ultimate states of reinforced concrete structures and shear bonds that create a spatial system. This paper uses computer simulation to study the stress-strain state of the welded bond under the action of shear and torque. Two joint models are considered, which are subject to only shear and shear with torsion. The results show the process of destruction of the joint, deformation of the shear walls to be joined, and a decrease in the rigidity of the connection. The study is useful for understanding the mechanisms of twisting effects during translational and rotational vibrations of a building.
Application of automated monitoring using hydrostatic leveling sensors in the Moscow metro
Authors: Milchevskiy Pavel
Published: August 2023

The article discusses the experience of using a domestically manufactured «Monitron» automated hydrostatic leveling system for monitoring nearby structures during the construction of the Moscow Metro. Based on the real-time settlement measurements, the tunneling parameters and protective measures for existing buildings were optimized.
Deformation of concrete under long-term influences of different types
Authors: Arleninov Petr
Published: August 2023

Introduction: Creep deformation of concrete depends at the character of stress state (compression, tension, bending, etc.). At this moment in our country as well abroad the chief parameter which determine by results of long tests concrete sample is the creep of concrete. These tests are done in the mode of uniaxial compression in spring units for one or several specimens, which simulates the compression of walls and columns. But in addition to centrally compressed elements, bending is present in an important part of structures (extracentral compressed columns, slabs, beams, etc.). In unique and difficult constructions massive reinforced concrete elements (foundations, elements of supports for equipment, columns of the lower floors of high-rise buildings, etc.) are often used. In this case the real work of structures under longterm effect of loading differs at the experimental one. Objective: Design and approbation of these methods to concrete testing samples under conditions other than standard tests - in the bending and three-axial compression modes. Materials and methods: In this scientific article describe the methodology of experimental setup for investigation of creep concrete specimens in the bending mode and in the mode imitating three-axial compression, describes the parameters of testing devices, specimens under test and principles transmission of load. Results: In this scientific article results of the experimental studies are presented in the graphical form in the article; their analysis is fulfilled. Conclusions: The perspectivity of the suggested approaches to the testing of concrete specimens for long-term loads has been shown, and recommendations for changes in GOST 24544 have been prepared.
The effect of columns twisting on the behavior of steel frame of industrial building
Authors: Tusnina Olga
Published: August 2023

The bracing system plays a very important role in the steel frame of an industrial building. The braces ensure the fixation of structures and their required effective lengths, give the frame overall spatial stability and geometric invariability. The scheme of bracing system significantly affects the behavior of the frame and the distribution of forces in its elements. The influence of the design solution of vertical bracing systems along the columns on the stress-strain state of the frame is studied in the article. It is shown that when using solid I-columns with the large web height (over 500 mm), to prevent their twisting and excessive displacements, it is necessary to fix both flanges of the columns in the longitudinal direction. That is why, the use of a single-plane vertical bracing system for the columns with the large web height is not recommended. For this, either two-plane braces can be used (allowing to reduce the twisting angle of the columns by 95%), or various options for fixing the flanges of the columns to struts or other structures (provide a reduction in the twisting angle of up to 88%).
Creep of an inhomogeneous polymeric cylindrical shell under heating
Authors: Andreev V.I. , Polyakova I.M.
Published: August 2023

The article presents the calculation of a polymer thick-walled cylindrical shell, taking into account creep under the action of a uneven temperature field. The relevance of the work lies in the widespread intro-duction of polymer pipes in the repair and construction of pipelines for heating, sewerage, and water supply systems. The problem is solved in an axisymmetric formulation under plane deformation conditions. The calculation is based on the non-linear Maxwell-Gurevich equation, which is widely used in the calculations of polymer structures.

In the problem under consideration, the cylindrical shell is in a flat de-formed state. It is also believed that temperature is a function of radius and time.
Static modes of an electromagnetic working shaft (EMWSh) and an electro-electromagnetic working shaft (EEMWSh) with the inclusion of a capacitor in the rotor circuit of the motors
Authors: Abidov Kudrat , Dadadjanov Kazim , Sobitov Sarvar
Published: August 2023

In this paper, the issues of ensuring the statically stable operation of a two-motor electric drive are considered, a fundamentally new system of coordinated rotation of asynchronous motors based on an electromagnetic working shaft (EMWSh) has been developed. A distinctive feature of EMWSh is the connection of the rotor windings of two or more motors to the power windings of an induction rheostat (IR) and capacitors. The issues of practical application of EMWSh and electroelectromagnetic working shaft EEMWSh with the inclusion of a capacitor in the rotor circuit of motor systems in multi-motor electric drives of crane movement mechanisms and long conveyor lines are studied.
The devastating 06.02.2023 Turkey – Syria earthquake of extreme intensity XI: Aposteriori estimates and damage prevention
Authors: Karakozova Anastasia , Kuznetsov Sergey , Mondrus Vladimir , Bratov Vladimir
Published: August 2023

The recent devastating earthquake of Mw7.8 occurred on February 6, 20223 in the Kahramanmaraş region having extreme intensity (XI) on the modified Mercalli scale (MMS) caused the death of more than 52,800 people in Turkey and Syria, as well as severe damages to the infrastructure. The appearance of an unusually strong delta-like S-wave pulse in the seismogram of the main shock and its consequences are analysed, and possible measures to mitigate the possible future high intensity earthquakes are discussed.
Geometrically nonlinear buckling analysis of truss with length imperfection subjected to mechanical and thermal load using hybrid FEM
Authors: Bich Quyen Vu Thi , Ngoc Tien Dao , Thuy Van Tran Thi
Published: August 2023

This paper presents a novel hybrid FEM-based approach to establish the mathematical model for solving the nonlinear buckling problem of truss systems with length imperfection under mechanical and thermal load. due to constant temperature change-based hybrid FEM. The proposed approach deals with establishing hybrid types of truss elements, including perfect truss elements without thermal deformation and truss elements with length imperfection and thermal deformation. The equilibrium equation of both truss elements is established based on compatibility relationships considering geometric nonlinearity. The hybrid global equilibrium equations of truss systems are developed by assembling constructed perfect truss elements without thermal deformation and truss elements with length imperfection and thermal deformation. The incremental-iterative algorithm based on the arc-length method is used to establish calculation programs to solve the hybrid global equilibrium equation for investigating the geometrically nonlinear buckling behavior of the truss system. The numerical test is presented to investigate the buckling and post-buckling behavior of truss systems having some elements with length imperfection under thermal and mechanical load.
Computer simulation of load-bearing elements and junction units in the calculation scheme of multistory frame buildings
Authors: Malakhova Anna
Published: August 2023

In the last three decades, preference was given to the construction of monolithic buildings, but the construction of multistory frame buildings from prefabricated concrete is very relevant at the present stage. Therefore, there is a need to revise the normative base for the design of prefabricated housing construction, including the revision of standards for certain types of prefabricated reinforced concrete structures. Such work is currently being carried out taking into account the use of modern building materials, new technologies for the production of prefabricated structures and the erection of prefabricated buildings, as well as taking into account the widespread use of computer design methods in design practice. The Code of Rules for the design of multistory frame buildings in prefabricated concrete SP 356.1325800 was developed as an extension of the Code of Rules for the design of reinforced concrete structures SP 63.13330. The article reviews the normative and technical literature on the computer simulation of load-bearing elements and junction units of the calculation scheme of multistory frame buildings. The means of the LIRA software package for computer simulation are considered and a quantitative assessment of the stiffness of the connection in the hinged joint of the crossbar with the column, as well as a flat model for assessing the stress distribution in the cantilever of this joint, is proposed.
Аassessing the Distribution of Statistical Heterogeneity of the soil deformation modulus based on static soil sensing
Authors: Abera Nune Tigabu , Kirianova Lyudmila
Published: August 2023

Cone penetration testing (CPT) has become one of the most commonly adopted in situ tests for site investigations, due to its reliability and repeatability of the measurements and the potential for direct use in design. CPT data we performed to a depth 5m in sandy soils within an area of 50x50m2 of 232 datasets, the significant of cone resistance force were analysis used statistical methods. The heterogeneity of soil deformation modulus was vertical and horizontally in three-dimensional plane analyzed. Data was shows vertically heterogeneity soil deformation but horizontally not heterogeneity.
Distribution of the modified statistic in the two-sample problem
Authors: Chiganova Nadezhda
Published: August 2023

At a time when modern production reaches colossal proportions, huge funds are spent on experimental research and testing of construction structures and materials with a view to their further technological improvement. Reducing such costs, accelerating ongoing research and optimizing the process of analyzing test results are significant challenges in the development of modern science. Due to the destructive nature of many tests, it is not possible to measure two or more parameters on the same object. The solution of such important tasks as reducing the duration of tests, calculating reliability in an alternating mode, and reproducing operating modes in laboratory conditions requires knowledge of functional, correlation and a number of other dependencies. These and other reliability problems led to the need to plan accelerated tests, according to the results of which it would be possible to test various hypotheses about simultaneously unobservable parameters. In many problems of the theory of accelerated testing, it is required to check the presence of a functional relationship between failures of construction products in various operating modes. This paper proposes a different approach to solving such a problem, which makes it possible to optimize the process of statistical analysis.
Development of software based on spectral characteristics for wind load
Authors: Sergey Saiyan , Daniil Sinyakin , Alexander Paushkin
Published: August 2023

A method is proposed for processing data from experimental or numerical simulation of wind loads and impacts in order to obtain spectral characteristics, which will make it possible to more correctly calculate the response of a structure, in particular, take into account the resonant and turbulent components that affect the stress-strain state of structures. In the Python programming language, the WIND SPECTRUM software module was written, designed to process simulation data based on spectral characteristics, which implements the developed technique. Examples of processing the wind effect obtained from the results of numerical simulation in the ANSYS CFX software package are also given.