bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudo Comparativo das Técnicas Cirúrgicas para o Tratamento da Rizartrose em um Centro de Referência
Authors: Muniz Matheus Torres , Monteiro-Oliveira Gabriela , Crivelini Paula Foresto , Manfroi Michaela Longoni , Serrano Sara Dadona Correia , Saheb Ricardo Lucca Cabarite , Rezende Luis Guilherme Rosifini Alves
Published: January 2025

Introdução: A rizartrose é uma doença degenerativa da articulação da base do polegar, comum no cotidiano ortopédico e mais predominante no sexo feminino. O tratamento não-cirúrgico possui alta resolutividade, contudo, na sua falha, diversas técnicas foram descritas com resultados similares. O objetivo deste estudo é comparar retrospectivamente o resultado funcional de três técnicas cirúrgicas diferentes. Métodos: estudo retrospectivo de pacientes com rizartrose submetidos ao tratamento cirúrgico no complexo do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo entre janeiro de 2020 e dezembro de 2023. Resultados: O resultado funcional dos 65 pacientes, submetidos ao tratamento cirúrgico por três diferentes técnicas, apresentou diferença estatística para migração proximal do polegar, e para o resultado funcional em 12 meses, contudo, sem diferença funcional pós-operatória nos pacientes na população estudada. Conclusões: Apesar das alterações observadas, não há diferença estatística no tipo de técnica a ser utilizada na população estudada considerando os resultados funcionais.
PRACTICALITY OF LANGUAGE LEARNING APPLICATION FOR STUDENTS’ AUTONOMOUS LEARNING
Authors: Rochma Anis Firdatul
Published: January 2025

One of several techniques for increasing student autonomy is to include current technologies such as cell phones and tablet PCs. However, various challenges occur about the incorporation of current technology in the learning process, which appears to be ineffectual in producing such situations that learner autonomy is realized. The current study is intended to investigate the beneficial effects of Edmodo, Duolingo, Memrise, Socrative, and Quizlet using the SAMR paradigm to assist learners in increasing their language learning autonomy. Employing mobile applications certainly promotes autonomous language learning since it allows learners to not only study the language but also acquire the target language in order to increase their competency. However, teacher guidance is still required to help students achieve their language learning goals.
DEVELOPING ENGLISH SPEAKING MATERIAL USING BANJARESE LOCAL WISDOM AND WETLANDS FOR SENIOR HIGH SCHOOL STUDENTS IN BANJARMASIN
Authors: Laheba Sarah Meisya Vira , Chandra Noor Eka
Published: January 2025

The topic raised in this research is developing English speaking supplementary materials based on Banjarese local wisdom and wetlands. This topic was raised considering that the wetlands and local wisdom around the students were able to provide them with a context that could help them learn English that could be used in everyday life. If we look at the textbooks used by students in class, most of the examples and materials used are not based on the things around them. Therefore, this research was conducted to develop English speaking supplementary materials based on Banjarese local wisdom and wetlands which are valid and practical. The model used in this research and development is the ADDIE model. The ADDIE model is a model that has been used by many developers and stands for Analysis, Design, Develop, Implementation, and Evaluation. Based on the research that has been done, students think that they need supplementary materials based on Banjarese local wisdom and wetlands. In addition, after going through the designing, developing, implementation, and evaluation processes, it was found that there are two advantages of the supplementary materials. The first is the supplementary material was developed with needs assessment, thus, the materials developed is fit with the students of eleventh grade’s needs, teachers’ needs, and English subject syllabus for eleventh grade senior high schools. The second advantage is that the English speaking supplementary materials developed were valid and practical for use in classroom learning.
Problems of psychological assistance to cancer patients
Authors: Mustafin R. N.
Published: January 2025

Purpose of the study: to assess the problem of psychological assistance to cancer patients and ways to resolve this problem. Material and Methods. The search for relevant sources was carried out in Scopus, Web of Science, PubMed, elibrary, including publications from February 2005 to December 2023. Of the 534 scientific articles found, 53 were used to write the systematic review. Results. Cancer patients are characterized by a high incidence of anxiety, depressive disorders and suicidal thoughts. Research in recent decades has shown that although more than a third of cancer patients experience stress and more than half experience depression and anxiety due to a cancer diagnosis, many do not seek psychological help to address their problems. Stress leads to an increased risk of comorbid psychological disorders and suboptimal compliance with anticancer therapy, potentially leading to decreased health and chance of recovery. In addition, psychological well-being is a necessary component for the recovery of the patient’s body after therapy, especially with a favorable prognosis. Research has shown that relatives caring for terminal cancer patients also need psychological help. active use of the work of a psychologist in the treatment of cancer patients will improve treatment results, improve the quality of care provided and comply with the principles of personalized medicine. to optimize the provision of psychological assistance, it is necessary to take measures to expand and make it accessible, for which the optimal methods are to regulate it in the treatment plan for cancer patients. Conclusion. In the current healthcare system, it is necessary to widely introduce consultations with psychologists in the treatment of cancer patients, which will increase the effectiveness of therapy and patient survival. the task of the oncologist is to identify patients with psychological disorders, especially those prone to suicidal behavior, anxiety and depression, and to correctly explain to them the need to receive psychological help, thanks to which the patient will not only be able to get rid of his emotional problems, but will also make sure that he needs to continue the treatment prescribed by the doctor.
Impact of dose fractionation regimen of adjuvant radiotherapy on cosmetic outcomes after immediate breast reconstruction
Authors: Bryantseva Zh. V. , Novikov S. N. , Ulrikh D. G. , Krivorotko P. V. , Akulova I. A. , Yaganova T. S. , Tabagua T. T. , Zernov K. Yu. , Belyaev A. M.
Published: January 2025

Background. Evidence for the safety of using the hypofractionation (HF) regimen after immediate breast reconstruction (IBR) in patients with breast cancer is not well documented. the purpose of the study was a retrospective analysis of surgical treatment with IBR and postoperative radiation therapy (RT) in conventional fractionated (CF) and hypofractionated (HF) regimens in breast cancer patients. Material and Methods. a retrospective analysis of treatment outcomes was carried out in 219 breast cancer patients who underwent mastectomy with IBR using permanent implant or tissue expander. all patients received postoperative RT: 97 received CF RT (22–25 fractions of 2 Gy) and 122 HF RT (15–16 fractions of 2.66–2.7 Gy). Cosmetic complications were represented by reconstructive failure (RF). all patients underwent an analysis of the incidence of reconstructive failures (RF) or capsular contracture (CC) (Baker III–IV). Results. CF RT was performed in 97 women: 55 – after IBR using tissue expander and 42 using permanent implant. the median follow-up time was 61 months. Complications were observed in 37 women (35.1 %): RF in 22 cases (22.7 %) and CC in 12 (12.4 %) cases. the median time to RF was 8 months, CC – 48.5 months. after RT to the tissue expander, CC rate was 0 %, RF – 25.5 %. after RT to the implants, CC was revealed in 28.6 %, RF in 19 % cases. In patients who received HF RT, cosmetic complications were detected in 51 (41.8 %) of 122 patients. the median follow-up time was 34 months. RF was revealed in 22.1 % cases, the median time was 9 months. CC was observed in 24 women (19.7 %) with the median time of 27 months. after HF RT to the expander, CC was observed in 4.9 %, RF in 39 % of cases. After RT to the implant, CC was detected in 27.2 %, RF in 13.6 % of cases. no significant differences in the risk of complication between patients who received conventional or hypofractionated RT were found (р=0.19). after RT to the expander, no differences (р=0.18 and р=0.12). After RT to the implant, there were also no differences in the frequency of CC and RF (р=0.52 and р=0.42). Conclusion. There were no significant differences in the frequency of cosmetic complications after postoperative radiotherapy in conventional fractionation or moderate hypofractionation regimens.
Two-point superstring tree amplitudes using the pure spinor formalism
Authors: Kashyap Sitender Pratap
Published: January 2025

We provide a prescription for computing two-point tree-level amplitudes in the pure spinor formalism that provides finite results that agree with the corresponding expression in the field theories. In [J. High Energy Phys. 07, 139 (2019), Phys. Lett. B 800, 135078 (2020)], the same result was discovered in the bosonic strings with indications of generalization to superstrings in the Ramond-Neveu-Schwarz formalism. Pure spinor formalism is the unique super-Poincare covariant approach to quantizing superstrings [J. High Energy Phys. 04, 018 (2000)]. Since the pure spinor formalism is equivalent to other superstring formalisms, it verifies the above claim. We introduce a mostly BRST exact operator to achieve this.
Navigating global economic turmoil: The dynamics of oil prices, exchange rates, and stock markets in BRICS
Authors: Ahmed Haseen , Ahmad Siddiqui Taufeeque , Naushad Mohammad
Published: January 2025

The study aims to analyze the co-movement between oil prices, BRICS nations’ exchange rates, and stock markets. Grasping these interrelationships is essential for understanding how global energy price shifts broadly affect the economies, particularly those of developing nations.The study employs wavelet coherency analysis on daily data, examining the association between crude oil (Brent crude), exchange rates (Brazilian Real, Russian Rubble, Indian Rupee, Chinese Yuan, and South African Rand), and stock markets (BOVESPA of Brazil, Moscow Exchange of Russia, Nifty50 of India, Shanghai Composite of China, and JSE FTSE of South Africa) across both temporal and frequency domains.This study reveals strong comovements, especially during periods of global economic instability, such as the impact of the COVID-19 pandemic and the Russia-Ukraine war. During such periods, oil prices and stock market indices tend to move in tandem, while oil prices and exchange rates show an inverse relationship. The study also reveals a decoupling of crude oil from both share markets and exchange rates during normal economic conditions. This decoupling suggests that outside of a chaotic period, the relationships weaken. However, the co-movements among the variables for China are notably weaker, even during economic upheavals, than in other BRICS nations. Understanding these relationships can aid in informed decision making and strategies in the face of global economic turmoil.
AcknowledgmentThis study is supported via funding from Prince Sattam bin Abdulaziz University project number (PSAU/2025/R/1446).
GTAP-Migration (GMig2) for GTAP 11
Authors: Aguiar Angel , Walmsley Terrie
Published: January 2025

GMig2, the GTAP migration extension, is a globally consistent database of bilateral population, labor by skill, wages, and remittances that can be used for economic modeling of international migration issues. Although new databases have significantly improved access to migration data, information on the skills of migrant labor is incomplete and bilateral remittance data are unavailable. This paper examines the underlying data available and then outlines the assumptions and techniques used to construct bilateral data on migrant labor by skills, remittances, and wages.
Current Scenario in Associating Clinical COVID-19 Biomarkers for Developing Surveillance Platforms
Authors: Lakshmipriya Thangavel , Gopinath Subash C.B. , Chen Yeng , Sasidharan Sreenivasan , Subramaniam Sreeramanan , Gunny Ahmad Anas Nagoor , Md Ali Umi Fazara , Salimi M.N. , Fakhri Makram A. , Salim Evan T. , Thirugnanasambandan Theivasanthi
Published: January 2025

The novel coronavirus that caused the epidemic and pandemic resulting in the
acute respiratory illness known as coronavirus disease 2019 (COVID-19) has plagued
the world. This is unlike other coronavirus outbreaks that have occurred in the past, such
as Middle East respiratory syndrome (MERS) or severe acute respiratory syndrome
(SARS). COVID-19 has spread more quickly and posed special challenges due to the
lack of appropriate treatments and vaccines. Real-time polymerase chain reaction (RTPCR)
and rapid antibody tests (surveillance tests) are the two most used tests (confirmation
tests). However, the latter takes hours to complete, and the former may produce
false positives. Scientists have invested significant effort to create a COVID-19 diagnostic
system that is both highly sensitive and reasonably priced. Early detection of
COVID-19 is a major area of focus for sensing devices based on nanomaterials. This
overview enhanced insights into potential coronavirus biomarkers and, compared to earlier
studies, introduced new avenues. Further, it covers the development of COVID-19
diagnostic systems from an analytical point of view, including clinical markers and their
subsequent applications with biosensors.
Pyrazoline Derivatives: Exploring the Synthesis and Development of New Ligands for Anti-Cancer Therapy
Authors: Sharma Renu , Salahuddin  , Mazumder Avijit , Kumar Rajnish , Chauhan Anurag , Ahsan Mohamed Jawed , Yar Mohammad Shahar , Maqsood Ramish , Singh Saurabh
Published: January 2025

Pyrazoline is a 5-membered ring that has two adjacent nitrogen. It has gained advanced
attention from medical and organic chemists due to very low cytotoxic activities. It is applicable
and more applied in research fields and has various pharmacological activities, including cardiovascular,
anti-tumor, and anti-cancer properties. In this review, the main objective is to study the
pharmacological aspects of pyrazoline and its derivative analogs. The present synthetic pyrazolines
are better scaffolds, which show more biological and medicinal characteristics. These compounds
exhibit diverse pharmacological activities, showcasing their potential as promising candidates for
cancer therapy. Pyrazolines demonstrate remarkable anti-proliferative and apoptosis-inducing effects
on cancer cells, attributed to their distinctive molecular structure. This review highlights the
growing significance of pyrazolines in medicinal chemistry, emphasizing their role in designing
novel anticancer agents. The multifaceted properties of pyrazolines offer a compelling foundation
for further research, driving innovation in the quest for effective and targeted anticancer drugs.
Network Pharmacology Unveils Multi-Systemic Intervention of Panax notoginseng in Osteoporosis via Key Genes and Signaling Pathways
Authors: Wang Qiyue , Wang Xiaoping , Wu Kezhou , Wu Weiwei , Wei Zhantu , Feng Weili
Published: January 2025

Background:

Panax notoginseng (Burk.) F. H. Chen (PN) is a traditional Chinese
medicine that has been applied to prevent and treat osteoporosis. The mechanism of PN for osteoporosis
remained a mystery.

Objective:

The objective was to reveal the therapeutic effect and illuminate the possible mechanism
of PN for osteoporosis.

Methods:

The Traditional Chinese Medicine Database and Analysis Platform was searched to
screen the potent ingredients of the PN and to analyze the potential therapeutic targets for osteoporosis.
We excavated four disease databases to collect osteoporosis-related genes. After integrating
the gene expression profile of osteoporosis and the chemical-protein data of PN, a protein-protein
interaction network was constructed to demonstrate the interactions among the gene products.
GO function, KEGG pathway, and docking analyses were executed.

Results:

Network pharmacology obtained 31 active ingredients and 134 targets for the treatment
of osteoporosis. The key components were beta-elemene, quercetin, methyl palmitate, oleic acid,
and hexanal. The results of GO and KEGG analyses showed that Panax notoginseng was beneficial
for osteoporosis by influencing the main pathways including AGE-RAGE signaling pathway
in diabetic complications, TNF signaling pathway, IL-17 signaling pathway, p53 signaling pathway,
NF-kappa B signaling pathway, PI3K-Akt signaling pathway, MAPK signaling pathway,
FoxO signaling pathway, and Wnt signaling pathway, modulating inflammation, metabolism, cell
proliferation, cell survival, growth and angiogenesis. Panax notoginseng intervened in osteoporosis
through multi-components, multi-targets, and multi-pathways.

Conclusion:

This study illustrates the mechanism of Panax notoginseng for osteoporosis, providing
broader insights for novel research and developments of the Panax species for osteoporosis.
Development of Stabilized and Aqueous Dissolvable Nanosuspension Encompassing BCS Class IV Drug via Optimization of Process and Formulation Variables
Authors: Goel Surya , Agarwal Vijay , Sachdeva Monika
Published: January 2025

Background:

Nanosuspension has emerged as an effective, lucrative, and unequalled approach
for efficiently elevating the dissolution and bioavailability of aqueous soluble drugs. Diverse
challenges persist within this domain, demanding further comprehensive investigation and exploration.

Objective:

This study aims to design, develop, optimise formulation and process variables, and
characterise the stabilised aqueous dissolvable nanosuspension using chlorthalidone as a BCS class-
IV drug.

Methods:

Nanosuspensions of the chlorthalidone drug were prepared using a combination of topdown
and bottom-up approaches. Various polymers such as Pluronic L-64, F-68, F-127, and
Synperonic F-108 were used as stabilisers in this research. All important processes and formulation
variables, such as ultrasonication intensity and time, the concentration of the drug, organic solvent,
and stabilisers that may critically influence the characteristics of the nanosuspensions, were optimised.
Formulation screening was performed using the optimisation of process and formulation variables,
and the optimised nanosuspension formulation was assessed for particle size, PDI, surface
charge, morphology, in vitro drug release, and stability.

Results:

To select an optimised nanosuspension formulation, the effects of formulation and process
variables were investigated. These variables critically influence the development of a stabilised
nanosuspension. The outcomes revealed that the nanosuspension formulation containing pluronic F-
68 as a stabiliser in 0.6% w/v concentration and the drug in 4 mg/ml concentration were optimized.
The particle size and zeta potential of the optimised preparation were 110 nm and -27.5 mV, respectively.
The in-vitro drug release of chlorthalidone drug from the optimised nanoformulation was increased
up to 3-fold, approximately (88% in 90 min) compared with pure chlorthalidone drug (27%
in 90 min) because of the decrease in particle size. Moreover, stability studies indicated that the
crafted nanoformulation was stable at cold (4℃) as well as normal room temperature (25℃) for six
months.

Conclusion:

From the obtained results, it was concluded that the combination of top-down and bottom-
up approaches employed for the fabrication of oral nanosuspension is a remunerative and lucrative
approach to successfully resolve the perplexities associated with the dissolution rate of poorly
aqueous soluble BCS class-IV drug moieties such as chlorthalidone.
Anti-corruption activities of local governments
Authors:   Shikhtimer B. Magomedov Dagestan State University, Magomedov Shikhtimer B. , Gadzhiev Alisultan Sh. ,   Alisultan Sh. Gadzhiev Dagestan State University
Published: January 2025

Статья посвящена исследованию актуальных аспектов деятельности органов местного самоуправления по противодействию коррупции. В статье особое внимание уделено профилактической работе, осуществляемой органам местного самоуправления по противодействию коррупции, методам борьбы с данным явлением силами муниципалитетов, а также возможным мерам минимизации коррупционных проявлений. В результате проведенного анализа выявлены деяния коррупционной направленности, наиболее часто встречающиеся на уровне местного самоуправления, а также определены антикоррупционные меры, включая разработку кодексов поведения для должностных лиц, ужесточение контроля за финансовыми операциями, регулярное обучение сотрудников органов власти правилам этики и принципам борьбы с коррупцией, проведение регулярных антикоррупционных проверок и аудитов, обнародование информации о доходах и расходах должностных лиц, создание механизмов для принятия жалоб и сообщений о коррупционных нарушениях.
The role and importance of the units of the Patrol and Guard Service, the State Road Safety Inspectorate, the Road Patrol Service and district police commissioners in ensuring public order: features of the tactics of service
Authors:   Sergey P. Shubin Barnaul Law Institute of the Ministry of Internal Affairs of Russia, Shubin Sergey P. , Loktev Dmitry S. ,   Dmitry S. Loktev Academy of Management of the Ministry of Internal Affairs of Russia, Akkuzin Yuri A. ,   Yuri A. Akkuzin Volgodonsk branch of the Rostov Law Institute of the Ministry of Internal Affairs of Russia
Published: January 2025

В данной статье рассматривается роль и значение подразделений ППС (патрульно-постовая служба), ГИБДД (Госавтоинспекция), ДПС (дорожно-патрульная служба) и участковых уполномоченных полиции (УУП) Обеспечение правопорядка в обществе является одной из главных задач государственных служб. Различные подразделения, такие как патрульно-постовая служба, государственная инспекция безопасности дорожного движения, дорожно-патрульная служба и участковые уполномоченные полиции, активно участвуют в выполнении своих обязанностей с учетом особенностей каждой тактики. Исследование в статье подчеркивает значимость и важность их роли в обеспечении порядка и безопасности граждан. Авторы обращают внимание на то, что эти подразделения являются основой публичного порядка и благополучия в обществе, а их работа направлена на предотвращение преступлений и проявления правонарушений. Приведенная выше ситуация определяет актуальность темы исследования. Цель настоящего исследования заключается в изучении особенностей тактики несения службы данными подразделениями. Авторы подчеркивают, что для эффективного исполнения служебных обязанностей ППС, ГИБДД, ДПС и УУП необходимо обладать определенными навыками и компетенциями. Они должны быть готовы к любым ситуациям, с которыми они могут столкнуться в своей работе, и действовать в соответствии с установленными правилами и инструкциями. Исследование базируется на системе философских, общенаучных и специально-юридических средствах и методах познания, которые гарантируют объективность изучения выбранной темы. Завершается статья обсуждением значимости тактики, применяемой данными подразделениями. Таким образом, авторы подчеркивают, что правильно примененная тактика не только способствует поддержанию общественного порядка, но и предотвращает конфликты и насилие. Они обращают внимание на необходимость постоянного обучения сотрудников ППС, ГИБДД, ДПС и УУП новым тактическим методам и техникам для повышения их профессионализма и эффективности работы. В заключение статьи авторы отмечают, что подразделения ППС, ГИБДД, ДПС и УУП являются неотъемлемой частью правопорядка в обществе. Их эффективная работа основывается на правильно применяемой тактике, которая позволяет им успешно выполнять свои служебные обязанности и обеспечивать безопасность граждан. Отражаются проблемы нормативно-правового регулирования и предлагаются меры, направленные на их устранение.
Compensation for Harm in Kind: Topical Issues of Judicial Practice
Authors:   Elena N. Agibalova Volgograd Institute of Management, branch of RANEPA, Agibalova Elena N. , Tulaev Vladislav А. ,   Vladislav А. Tulaev Volgograd Institute of Management, branch of RANEPA
Published: January 2025

В статье рассмотрены особенности возмещения причиненного вреда в натуре на основе анализа практики применения судами ст. 1082 Гражданского кодекса Российской Федерации, регулирующей этот способ возмещения вреда, исходя из фактических обстоятельств дела. В ходе исследования авторами были выделены пять категорий дел, которые являются ключевыми при определении специфики возмещения вреда в натуре. В заключение сделаны выводы, раскрывающие особенности данного способа возмещения вреда.
Efficiency of Pre-Expanded Anterior Supraclavicular Artery Pedicled Skin Flaps: A Meta-Analysis Study
Authors: Alharbi Ziyad
Published: January 2025

The supraclavicular artery flap presents a promising solution for facial reconstruction challenges since 1997, surpassing limitations of traditional methods like the deltopectoral flap. Its extended pedicle and thin, pliable epidermis offer reliable outcomes with minimal donor site morbidity, making it a preferred choice for head and neck reconstruction. This systematic review evaluates the efficacy of pre-expanded supraclavicular artery flaps based on a comprehensive analysis. In accordance with the Preferred Reporting Items for Meta-Analysis (PRISMA) recommendations, this meta-analysis was carried out. A comprehensive search of electronic databases including PubMed, Google Scholar and Web of Science between 2013-2024. The search strategy utilized the following keywords: ["supraclavicular" AND "flap"]. Searches were limited to English-language articles. We also manually searched reference lists of relevant articles to identify additional studies. The inclusion criteria for the articles were as follows: (1) original research articles discussing the use of Pre-Expanded Anterior Supraclavicular Artery Pedicled Flaps; (2) English language publications; (3) human subject studies; and (4) studies reporting pertinent outcomes like flap viability, complications, or aesthetic results. Free, thoracic, deltoid and pectoral flaps were excluded. Reviews and studies written in languages other than English were eliminated. To determine the eligibility of the initial pool of 202 studies that were gathered from different sources, a rigorous screening procedure was carried out. Nine publications were subjected to a thorough full-text evaluation following the exclusion of 193 research studies that did not match the inclusion requirements. After this evaluation, only seven papers were deemed suitable for this meta analysis's inclusion. All studies reported successful outcomes of the flap procedures, indicating the effectiveness of pre-expanded anterior supraclavicular artery pedicled skin flaps in the sample. Wound healing outcomes varied across the studies, with 42.9% reporting excellent wound healing and 57.1% reporting good wound healing. This suggests overall favourable outcomes in terms of wound healing. Expansion in the area of the lifting site increases flap size and allows reconstruction of more extensive facial and neck defects in terms of function and aesthetics. The advantages of the pre-expansion are well reported and include the minor donor site morbidity, flap safety and reliability, and most importantly, its favorable match in color and texture to tissue of the head and neck area in addition to vascularity. Pre-expansion not only increases size and reduces thickness, but also enhances the vascularization process through a well-formed capsule enriched with vessels. Primary closure of the donor site can be achieved with tensionless technique due to the laxity of the skin after expander insertion.
PREDICTION OF CONVERSION OF LAPAROSCOPIC CHOLECYSTECTOMY TO OPEN CHOLECYSTECTOMY USING A PREOPERATIVE SCORING SYSTEM
Authors: KOLA CHANDRASEKHAR REDDY  , SASIDHARA RAO A  , JAYADURGA CHALAMALASETTY  , PRERANA RAJU GUDIMETLA  , SRIDHAR PUNYAPU  , RAVI GANJI
Published: January 2025

Objectives: The objectiveof the study is To use the Risk Score to predict conversion of laparoscopic cholecystectomy to open cholecystectomy and to evaluate whether this scoring method can be used routinely.
Methods : A Prospective Observational Clinical study conducted in 106 cases who underwent elective laparoscopic cholecystectomy were analysed prospectively both preoperatively and postoperatively using the scoring system.
Results:  A total of 106 patients were studied. The highest incidence of gallstone in present series is in the age group of 30 to 40 years. The gender ratio (Male: Female) is 1: 2.3. Of the 106 patients, all had cholelithiasis, 6 patients had GB wall thickening, 1 had impacted stone and none had peri-cholecystic collection. In the present study, Age >50, BMI >;27.5, H/O prior hospitalization for acute cholecystitis, wall thickening, vomiting’s, were significant predictors of difficult laparoscopic cholecystectomy. The conversion rate from laparoscopic cholecystectomy to open cholecystectomy was 12.3%. Of the total 19 cases falling under moderate risk 12 were converted to open cholecystectomy. Rest was managed and completed by laparoscopically. Only one case in the mild risk group was converted to open, reason being the short cystic duct. The most common intraoperative reason for conversion was adhesions in 10 patients, followed by frozen calots, short cystic duct and Mirizzi syndrome. The positive predictive value for easy prediction was 100%.
Conclusion: The scoring system used has got better significance in prediction of conversion from lap to open cholecystectomy.
Geoquímica ambiental de los isótopos estables de Zinc
Authors: Carrillo-Chávez Alejandro , Calvo-Ramos Daniela K. , Rueda-Garzón Luisa F. , Corona-Martínez Liliana , Muñoz-Torres Carolina , García-Martínez Rocío
Published: January 2025

La geoquímica ambiental de los isótopos estables del zinc (Zn) es un campo de investigación relativamente nuevo que se centra en la comprensión de los ciclos geoquímico y biogeoquímico del Zn en los sistemas naturales, usando el fraccionamiento isotópico del Zn como trazador de diversos procesos. Los isótopos de Zn son sensibles a una amplia gama de condiciones ambientales, incluidos los cambios en los estados de oxidación, la absorción biológica y la meteorización mineral. Esto los convierte en herramientas valiosas para estudiar las influencias tanto naturales como antropogénicas en el medio ambiente. En general, el Zn es unos de los metales más usados por la industria, es esencial en procesos orgánicos metabólicos (incluidos losdel ser humano) y es tóxico en altas concentraciones. Los isótopos de Zn se han utilizado para rastrear fuentes de  contaminación en suelos y aguas, especialmente en zonas afectadas por actividades mineras y emisiones industriales,  apoyando así las evaluaciones geoquímicas ambientales, y en las estrategias de remediación. La geoquímica de isótopos estables del Zn tiene implicaciones en varios campos de las geociencias, ciencias bioquímicas e incluso en las ciencias médicas. En este artículo se da información general de fuentes naturales de Zn, algunos de sus usos industriales, el Zn como elemento  esencial en metabolismo orgánico y su toxicidad. El principal enfoque está centrado en analizar algunos procesos de  fraccionamiento isotópico, explicar de manera general sus aplicaciones, definir las metodologías de preparación de muestras en laboratorio, así como los métodos analíticos modernos para medir el fraccionamiento isotópico del Zn, y finalmente  presentar algunos datos preliminares de mediciones isotópicas de Zn de proyectos vigentes en Instituto de Geociencias-UNAM, Campus Juriquilla.
¿Una Tierra sin campo magnético? Un fenómeno comprendido hasta 1919
Authors: Chacón-Hernández Francisco
Published: January 2025

Al día de hoy, diferentes estudios nos han permitido conocer más sobre el origen, comportamiento y funcionamiento del campo magnético de la Tierra (cmT). Este fenómeno, cuyo conocimiento ha requerido de siglos de observaciones y estudios para responder inquietudes e interrogantes milenarios, aún plantea ciertas dudas sobre su pleno funcionamiento. No obstante, durante el siglo XVII, la pregunta que muchos hacían sobre si la Tierra era en sí un campo magnético gigante que seguía los principios físicos de un imán, comenzó a ser cada vez más considerada. Esto permitió obtener a principios del siglo XX, en el año de 1919, evidencias concretas solo de carácter empírico y experimental que permitieron hacer las primeras suposiciones sobre el origen del cmT, correlacionando sus causas-efectos e integrando los diferentes tipos de mecanismos y fenómenos que ocurren en el interior y exterior de la Tierra. Por tanto, en este escrito, se volverá al pasado para intentar revisar aquellos supuestos milenarios que se hicieron sobre el magnetismo y el cmT. Así mismo, se explica de forma general y sin detalles  técnicos el origen y funcionamiento del cmT, lo que en realidad representa este fenómeno y cómo éste guarda correlación con el funcionamiento total del planeta Tierra en constante evolución.
orígenes autoritarios del Derecho Administrativo y la necesaria revisión conceptual de "interés público"
Authors: Rodrigues João
Published: January 2025

Este artículo reúne, de manera concisa, algunas reflexiones sobre el alcance, la amplitud y la operatividad práctica del concepto administrativo de interés público. La metodología aplicada consistió en revisión bibliográfica, investigación histórica y formulación de hipótesis de trabajo. El objetivo trazado es intentar encontrar bases más sólidas y funcionales para convertir el concepto de interés público, verdaderamente, en el pilar de todo el edificio administrativo. El gran desafío, en este sentido, es encontrar, dentro del contexto jurídico-político, un estándar razonable para la concreción de los intereses adecuados en una síntesis trascendental.
Environment as a Victim: overcoming the human-centric Paradigm of Rights
Authors: Sanabria-Rangel Alvaro Augusto
Published: January 2025

The present article evaluates the profound impact that recognizing the environment as a potential victim has for the enforceability of environmental rights and the particularities of the Latin American juridical systems that have been critical in this development affecting how environmental rights and protections are considered, in particular the understanding of the environment as a victim. In the 1990s, the In Dubio Pro Natura principle was developed via judicial decisions. This principle is understood as a separate principle of international law that requires authorities to interpret laws and regulations in the most favourable manner to the interests of nature. In the first decade of the 2000s, Ecuador and Bolivia constitutionalized environmental rights. This process embraced non-western legal approaches and traditions from indigenous peoples. More recently, Colombia’s restorative justice system has acknowledged the environment as a direct victim of their internal armed conflict. The process that has taken place in the Latin-American region represents a case study on challenging the human-centred paradigm of rights. This article discusses the significance and potential of this recognition for the enforceability of environmental rights.
 
RESUMEN: El presente artículo evalúa el profundo impacto que el reconocimiento del ambiente como una potencial víctima tiene para la exigibilidad de los derechos ambientales y las particularidades de los sistemas jurídicos Latinoamericanos que han sido críticos para este desarrollo que afecta cómo los derechos ambientales y sus protecciones son evaluados, en particular la interpretación del ambiente como víctima.  En la década de 1990, el principio In Dubio Pro Natura fue desarrollado por medio de decisiones judiciales.  Este principio es entendido como un principio independiente de derecho internacional que exige a las autoridades interpretar las leyes y regulaciones de la forma más favorable a los intereses de la naturaleza.  En la primera década del siglo XXI, Ecuador y Bolivia constitucionalizaron los derechos ambientales.  Este proceso acogió enfoques y tradiciones no occidentales provenientes de los pueblos indígenas.  Más recientemente, el sistema de justicia restaurativa de Colombia ha reconocido al ambiente como víctima directa de su conflicto interno armado.  El proceso que ha tenido lugar en Latinoamérica representa un caso de estudio que cuestiona el paradigma humanocentrista de los derechos. Este artículo discute la importancia y potencial de este reconocimiento para la exigibilidad de los derechos ambientales.
Hacia la exigibilidad del derecho a la energía: instrumento del derecho a la vida y vivienda adecuadas
Authors: Hessling Herrera Franco David
Published: January 2025

Se busca dar cuenta de la emergencia del derecho a la energía recuperando antecedentes que permiten considerar el acceso a una energía limpia, asequible y segura como un derecho humano. A partir de ciertos fallos recientes de los sistemas de protección de derechos humanos se lo ha recogido como elemento instrumental de otros derechos consagrados en instrumentos con rango constitucional. Para tal propósito se emplea una metodología propia del campo de los estudios críticos de los derechos humanos: el “diamante ético” de Herrera Flores. A partir de ese recorrido por los antecedentes teóricos, políticos y jurídicos del derecho a la energía como derecho humano se presenta una sistematización en clave de soft-law y derecho comparado. Por último, se propone retomar estos antecedentes y el debate emergente sobre el derecho a la energía para concatenarse con procesos con plena vigencia en la actualidad, tales como la transición energética.
Analogy and legal reasoning: a cluster of open questions
Authors: Zorzetto Silvia
Published: January 2025

The analysis proposes a minimal concept of analogy that represents a lowest common denominator among the many models that have been proposed by legal theorists and jurists over time. Such a minimal concept is an explanatory tool to navigate the 'jungle' of questions surrounding this argument that hides behind truisms and trends in contemporary jurisprudence. This analysis sets out some of the issues surrounding analogy: (i) at the level of construction and rhetoric, its relationship to exemplarism in law, legal metaphors and fictions; (ii) at the level of interpretation and adjudication, its relationship to other legal arguments, precedent, legal principles, extensive interpretation and the nature of the source/target norm; (iii) at the level of justification, the axiological and practical dimensions of analogy and the relationship with particularism and universalism; and finally (iv) the values and scope commonly associated with analogy
Automatic Bottle Filling Unit using PLC
Authors: Lohar Rutuja
Published: January 2025

This research paper explores the design and implementation of an automatic bottle filling system controlled by a
Programmable Logic Controller (PLC). The main objective of this study is to improve the efficiency and precision of filling
operations, particularly in industries such as beverage production, pharmaceuticals, and chemicals. The system aims to replace
the traditional manual bottling processes, which often suffer from human error, inconsistencies, and inefficiency. By integrating
various sensors, actuators, and a PLC-based control system, this automated filling unit enhances speed, reduces waste, and
ensures precise filling to the required levels. The PLC coordinates all the activities, including bottle detection, liquid dispensing,
and capping, contributing to an optimized and error-free production process.
Integration of Ideological and Political Education into "Financial Management" Curriculum: Teaching Reform and Practice Research
Authors: Lan Juan
Published: January 2025

With the continuous deepening of higher education reform, integrating ideological and political education with
professional course teaching has become an important direction for educational innovation. This paper takes the "Financial
Management" course as an example to explore the integration strategies, implementation paths of ideological and political
education in professional teaching, and its impact on improving teaching quality and students' comprehensive qualities. This
paper employs literature analysis, case study, and teaching experimentation methods to construct a teaching model for
ideological and political education in financial management courses, proposes specific integration strategies, and validates the
effectiveness of these strategies through empirical research. The research results show that the effective integration of ideological
and political education can significantly enhance students' professional ethics and social responsibility, while also promoting
students' in-depth understanding and application ability of professional knowledge. This paper has certain theoretical and
practical significance for promoting higher education curriculum reform and achieving the organic unity of knowledge
impartation and value guidance.
The Convergence of Renewable Energy and Aquacultural Engineering for a Sustainable Food System
Authors: Roy Priyanka
Published: January 2025

Renewable energy and aquacultural engineering combine to provide a disruptive approach to developing a sustainable
and resilient food supply. This area of aquacultural engineering would automate feeding systems, oxygenation, recirculating
aquaculture systems, and water quality monitoring by integrating renewable energy sources such as sun, wind, hydropower, and
bioenergy. In order to improve the efficiency of freshwater and marine aquaculture systems, energy from renewable sources will
reduce waste and maximize the usage of IoT and AI toward resource efficiency. For the agricultural sector, implementing
renewable energy will diminish greenhouse gas emissions, reduce operations cost, and create energy independence for
farms especially off-grid and remote ones. Diversification promotes eco-friendly practices such as IMTA and biofloc systems,
increasing the organization's resilience to energy volatility and climate change. Although there are obstacles in the form of high
upfront costs and integration complexity, renewable technology and hybrid systems do offer a viable solution. Through the
preservation of ecological balance and the provision of a sustainable food supply for future generations, this combination of
renewable energy and aquacultural innovation has the potential to completely transform aquaculture.
Revolutionizing Bone Cancer Detection: Real-Time Medical Imaging Analysis Using YOLOv8 for Enhanced Diagnostic Accuracy and Speed
Authors: K Shafaat Basha
Published: January 2025

Bone cancer also classified as one of the unapproachable cancer for being diagnosed because its symptoms are always
vague, and in most cases, may not be easily differentiated even in x-ray, MRI, and CT images. Prior screening techniques
involve use of these images for diagnosis through interpretation by radiologists, which is a slow process, and may be prone to
human error, resulting in slow diagnosis and worse patient outcomes. With improving healthcare diagnosing, artificial
intelligence (AI) and deep learning models are better options as the industry moves forward.
This paper offers a new method in the early detection of bone cancer in real-time using YOLOv8, the most performed object
detection model. For these reasons, YOLOv8 was chosen because it provides a relatively fast image throughput and detection
accuracy. The proposed framework utilizes a dataset that contains bone cancer image that is labeled in addition performs an
optimization with specific considerations for the model to cater for detecting cancerous lesions on bone structures. It also
connects to medical imaging devices so that it can return feedback and a diagnosis in a fraction of the time that would usually be
taken to analyze images. Bone cancer also classified as one of the unapproachable cancer for being diagnosed because its
symptoms are always vague, and in most cases, may not be easily differentiated even in x-ray, MRI, and CT images. Prior
screening techniques involve use of these images for diagnosis through interpretation by radiologists, which is a slow process,
and may be prone to human error, resulting in slow diagnosis and worse patient outcomes. With improving healthcare
diagnosing, artificial intelligence (AI) and deep learning models are better options as the industry moves forward.
This paper offers a new method in the early detection of bone cancer in real-time using YOLOv8, the most performed object
detection model. For these reasons, YOLOv8 was chosen because it provides a relatively fast image throughput and detection
accuracy. The proposed framework utilizes a dataset that contains bone cancer image that is labeled in addition performs an
optimization with specific considerations for the model to cater for detecting cancerous lesions on bone structures. It also
connects to medical imaging devices so that it can return feedback and a diagnosis in a fraction of the time that would usually be
taken to analyze images.
Voice-Enabled Inclusive ECommerce Platform for Visually Impaired and Non-disabled Users
Authors: A Libo Joel
Published: January 2025

The Voice-Enabled Inclusive E-Commerce Platform is designed to provide a seamless shopping experience for both
visually impaired and non-disabled users through advanced voice command technology. The platform enables users to navigate,
browse, filter products, and manage shopping carts entirely hands-free, enhancing accessibility and independence for visually
impaired individuals. Built on Flask with a focus on accessibility, the system incorporates secure user authentication, session
management, and dynamic product interaction. Voice commands, processed through the Web Speech API, allow users to log in,
register, and complete transactions effortlessly. The platform is designed to be inclusive, ensuring a unified experience for all
users, while maintaining essential security protocols like password hashing and session management. Future enhancements
include multilingual support, personalized AI-driven recommendations, and advanced security features. This platform
exemplifies how technology can create an equitable e-commerce environment.