bluuebunny/crossref_metadata_2025 huggingface dataset:
THE BIORESOURCE COLLECTION OF PEAR (PYRUS L.) AT THE MAIKOP EXPERIMENTAL STATION OF THE FEDERAL RESEARCH CENTER OF N.I. VAVILOV INSTITUTE OF PLANT GENETIC RESOURCES: HISTORY OF FORMATION AND USE IN BREEDING
Authors: Shapovalov M. , Bandurko I. , Cherchesova S.
Published: October 2024

The article discusses the history of the formation of the fruit crop collection establishment and its component – the collection of pears (Pyrus L.), maintained at the Maikop Experimental Station (MES) of the Federal Research Center of N.I. Vavilov Institute of Plant Genetic Resources (VIR). The pear bioresource collection founded in 1930 at the initiative of academician N. I. Vavilov, is one of the oldest and the most extensive in the Russian Federation. Currently, the collection consists of 1123 specimens, including 875 cultivars, 33 hybrids, 30 species, 215 varieties. Over 80 promising new pear forms and varieties with a range of economically valuable traits were bred at MES VIR using the specimens from the collection. As a result of long-term in-depth biological and economic research on the pear gene pool at MES VIR, varieties – serving as sources and donors of economically valuable traits in key areas of breeding (limited crown volume, early fruiting, late flowering, disease resistance, high marketing and taste attributes, increased fruit weight, bright fruit colouring, winter hardiness, varieties with parthenocarpy traits) were identified.
THE FIRST EVIDENCE OF SUCCESSFUL NESTING OF THE GREATER FLAMINGO (PHOENICOPTERUS ROSEUS PALLAS, 1811 (AVES, PHOENICOPTERIFORMES) IN CRIMEA
Authors: Grinchenko A. , Prokopov G.
Published: October 2024

Over the past decade, the Sivash Bay has undergone significant transformations due to the blocking of the North Crimean Canal. It resulted in a considerable increase in salinity, which facilitated the establishment of a feeding base for the Greater Flamingo (Phoenicopterus roseus Pallas, 1811), characterized by a substantial development of brine shrimp (Artemia sp.) and chironomid larvae (Chironomidae). The warm winters of recent years and the establishment of a rest zone in the Sivash Bay near the base of the Arabat Spit led to the formation of a nesting colony of the Greater Flamingos. The establishment of the colony commenced in mid-April 2024, with egg-laying beginning in the first decade of May, and the first chicks hatching in late May to early June. The colony reached its maximum size by June 22, comprising 320 adult birds and approximately 110 chicks of two generations, along with over 30 nests still incubated by flamingos. Preliminary data regarding the molting patterns of flamingos in Crimea were collected. It was revealed that nesting birds exhibit a sequential molting pattern, allowing them to retain their flight capability. The formation of a flamingo breeding colony is unique for the Russian Federation. To preserve the breeding conditions of these birds, it is essential to expand the wildlife sanctuary of regional significance “Arabatsky” to the base of the Arabat Spit, including the adjacent waters of the Sivash Bay. Furthermore, a resting zone of at least 2 km should be designated around the sandy spit where the flamingo colony was formed in 2024, prohibiting the harvesting of Chironomidae and Artemia sp., as well as banning windsurfing.
CONCENTRATION OF MERCURY IN SUSPENDED MATTER IN SURFACE SEAWATER OF AZOV-BLACK SEA BASIN
Authors: Stecyuk A. , Egorov V.
Published: October 2024

The content of mercury in water and suspended matter in the Black Sea and the Sea of Azov was studied. The research established that in 2020 the concentration of total form of mercury in water did not exceed the maximum permissible values (100 ng×l−1). In the Black Sea it varied from 12 to 65 ng×l−1, and in the Azov Sea from 22 to 59 ng×l−1. The variation in the coefficients of mercury accumulation in suspended matter was (14.5–1666.7)×103 units in the Black Sea and (14.5–272.7)×103 in the Sea of Azov. The maximum concentrating ability of suspended matter was observed in the Black Sea, at the outlet from the Kerch Strait, which may indicate an increased anthropogenic impact on this water area during the study period. Two trends were determined: the saturation of suspended matter with mercury in the Black Sea along with an increase in its concentration in the aquatic environment, and the decrease in mercury content in suspended matter in the Sea of Azov as the pollution of water with mercury increases. It was found that, given the radical difference in trends of changes in mercury concentrations in suspended matter in Black and Azov Seas, the parameters of the approximating exponential relationships between accumulation coefficients and mercury concentration in water for the Black Sea and the Sea of Azov were not statistically significantly different, and the combined dataset sample for both seas was adequately described both by exponential and power functions. The results obtained generally indicated a decrease in the concentrating ability of suspensions with increasing concentration of mercury in water. The mercury pool on suspended matter varied from 3 to 29 % for the Black Sea and from 6 to 55 % for the Sea of Azov.
THE ECOPHYSIOLOGICAL RESPONSE OF SIBERIAN SPRUCE TO DENDROPHAGE DAMAGE
Authors: Vedernikov K.
Published: October 2024

The article presents data on the study of the peculiarities of the biochemical composition of coniferous wood under conditions of their mass drying. The research was conducted in the European part of the Russian Federation on the territory of the Udmurt Republic, within two forest areas. The subjects of the research are spruce plantations of the acidic type. According to the results of the study, samples from individuals of different life conditions were selected for physiological assessment. Physiological studies were carried out by extracting samples with solvents of different polarities. The wood was analyzed for the total content of extractives – water-soluble and resin-like compounds, as well as tannins. The content of extractives and their composition vary greatly from one sample area to another. The quantity and component composition of extractive compounds are influenced by the vital state of plants and the growth place condition. Significant values of extractive compounds are observed in stands of coniferous-deciduous forests. In these areas, the processes of death of spruce forests are proceeding at the most intensive pace. In trees of satisfactory condition, the content of all components of extractive substances is higher in comparison with individuals of other life categories, especially tannins. A high content of polyphenolic compounds is observed in all studied individuals from plantations with an unfavorable sanitary condition. The obtained data on the peculiarities of the content of extractive substances in spruce wood can be used to select trees to create sustainable forest crops.
ORNITHOGEOGRAPHIC ZONING OF THE CRIMEAN PENINSULA
Authors: Kostin S.
Published: October 2024

As a result of a comprehensive analysis of the avifauna of Crimea 21 districts were identified, taking into account the distribution of ecological and faunal groupings of birds according to zonal and biotopic divisions, the scheme of their dominance, the study of the relationships between species of various faunal complexes and types, as well as the presence of specific species. The border of the Sahara-Gobi and European subregions runs along the northern foothills. The species of Nomadic-type and tropical groups predominate in the lowland Crimea, and species of Nemoral complexes of European and Euro-Chinese types predominate in the mountain-forest belt. The northern foothills which are characterized by the transitional nature of the fauna that bears significant similarities with lowland Crimea (53 %), are attributed to the Crimean Foothills District. A belt of hemixerophytic forests, woodlands, tomillaries and savannoids of the Southern coast forms the Southern Coastal District. Both districts are considered part of the Western European Province of the European Subregion.
Efficacy of Topical and Submucosal Local Anesthesia in Reducing Pain and Anxiety during Inferior Alveolar Nerve Block
Authors: Wasif Aaminah Salman , Najeeb Waniya , Gull-e-Dawoodi  , Maryam Aslam  , Hammad Hassan  , Hassan Muhammad
Published: October 2024

Objective: To compare the efficacy of topical and submucosal local anesthesia in reducing pain and anxiety during inferior alveolar nerve block. Study Design: Quasi-experimental study. Settings: Institute of Dentistry, CMH Lahore Medical College, Lahore Pakistan. Duration: From December 2021 to January 2023. Methods: Patients were divided into three groups. In group 1, conventional IANB was given, in group 2, submucosal anesthesia was given before IANB; and in group 3, topical anesthesia was given before IANB. An interview-administered questionnaire was used to mark their level of anxiety and pain. Mann-Whitney U and Kruskal Wallis were used to compare the mean VAS and MDAS scores. Results: The mean VAS score was 3.95 ± 1.74. Younger age, females, and the patients in the simple IANB group reported higher VAS scores. Patients in the simple IANB group had significantly higher VAS scores, followed by the patients who received submucosal and topical anesthesia prior to INAB (p=0.01). The mean MDAS score of the patients was 10.16. Middle-aged adults, females, and the simple IANB group reported higher mean MDAS scores. Males (p<0.001) and those who received topical anesthesia (p=0.019) were less anxious. Conclusion: The use of topical or submucosal anesthesia before administering IANB can effectively reduce pain and anxiety. The highest anxiety and pain perception levels were found in the simple INAB group, while the lowest pain as well as anxiety levels were reported in the topical anesthesia group.
Effectiveness of Orthopedic Bracing in the Management of Adolescent Idiopathic Scoliosis: A Randomized Controlled Trial
Authors: Imran Ahmed  , Bushra Sajid  , Ashfaque Hussain Mirjat  , Aamir Usman Memon  , Kazi Sadia , Mozna Talpur
Published: October 2024

Background: Scoliosis is a complex spinal condition that often requires bracing as a significant treatment to prevent spinal deterioration in adolescent idiopathic scoliosis (AIS). Adaptation can be difficult; the effectiveness of support is well documented and treatment aims to improve the spine and body's quality of life. Objective: The objective of the study is to evaluate the effectiveness of bracing as a treatment for preventing spinal deterioration in adolescent idiopathic scoliosis (AIS) and to assess its impact on the quality of life and spinal health of patients. Study Design: This one-arm quasi-experimental study. Settings: Outpatient department of tertiary care hospitals of Sindh i-e Civil Hospital, Suleman Roshan and Memon Charitable Hospital, Pakistan. Duration: One year from 15-04-2023 to 15-04-2024. Methods: The study evaluated the effectiveness of bracing in 20 AIS patients aged 10-17 with Cobb angles of 20°-40°, excluding those with prior treatments or other pathologies. Patients received thoracolumbosacral orthoses (TLSO) and were monitored regularly, required to wear braces 23 hours daily. Assessments of trunk inclination, Cobb angle, and body image were conducted every six months over a year, with radiographic and shoulder balance evaluations performed and bisphosphonates were advised during visits. Results: The study involved 20 AIS patients (11 females, 9 males) with a mean age of 13.8 years and an average baseline Cobb angle of 27.6 degrees. Over 12 months, the mean Cobb angle significantly decreased to 23.12 degrees, indicating a meaningful reduction in spinal curvature. Notable improvements were observed from baseline to 6 months (mean reduction of 2.23 degrees, P < 0.001) and from 6 months to 12 months (mean reduction of 2.89 degrees, P < 0.001), demonstrating significant and clinically meaningful corrections in spinal alignment. Conclusion: The findings highlight the effectiveness of bracing in reducing spinal curvature in adolescents with scoliosis, suggesting promising interventional strategies to improve patient outcomes.
Diagnostic Accuracy of Magnetic Resonance Spectroscopy for Differentiation of Benign and Malignant Brain lesions using Histopathology as a Gold Standard
Authors: Amber Manzoor  , Nayab Aliya  , Marryum Mukhtar  , Muhammad Qasim Khan  , Aamna Gilani
Published: October 2024

Background: Academic sources showed that MRS has a high accuracy rate for recognizing malignant brain lesions and is more reliable than any other modality. However, there is much less data for the accuracy of MRS. So, more studies are needed to validate the evidence. MRS is a minimally disruptive technique that shows the neurochemical profile of the brain. Objective: To find the diagnostic precision of MRS for differentiation of aggressive & benign cerebral focal lesions taking1histopathology as the ultimate criterion. Study Design: Cross-sectional study. Settings: Imaging department, Madinah Teaching Health Institution, Faisalabad Pakistan. Duration: Six months from December 20, 2020 to June 21, 2021. Methods: A total of 155 Radiology Department patients fulfilling the selection criteria were enlisted. Then all patients underwent MRS using 3T. Findings were documented & patients were labeled as positive or negative. Then, the biopsy sample was sent to the hospital laboratory for histopathological evaluation after being under the supervision of the surgical team. Results: The mean age was 47.17±16.46 years. There were 69(44.5%) males & 86(55.5%) females in this study. The mean duration of symptoms was 11.44±2.79. The sensitivity and specificity of MRS were 90.79% and 86.08%, or PPV & NPV were 86.25% & 90.67%, respectively, and the 1overall diagnostic accuracy was 88.39%. Conclusion: Results demonstrate that the sensitivity (90.79%) and specificity (86.08%) of MRS are high enough to differentiate between malignant & benign brain lesions.
IMPACT OF FAKE NEWS ON THE CREDIBILITY OF NATIONAL HINDI NEWS CHANNELS: A STUDY OF VIEWER PERCEPTIONS IN UTTARAKHAND
Authors: Kumar Pawan Lalchand , Kulshreshtha Ashish
Published: October 2024

This study investigates the impact of fake news on the credibility of national Hindi news channels, focusing on viewer perceptions in Uttarakhand. As misinformation proliferates across media platforms, understanding its effects on audience trust and news consumption habits is crucial for maintaining an informed citizenry and a healthy media ecosystem.The research uses a survey methodology to examine viewers' news consumption patterns, awareness and perception of fake news and the subsequent impact on channel credibility. Questions explore viewing frequency, preferred channels and perceived exposure to misinformation. The study assesses viewers' confidence in identifying fake news and investigates which news categories are most susceptible to false information.Central to this investigation is how fake news affects trust in Hindi news channels. The survey measures changes in viewer trust levels and explores factors influencing news credibility judgments. It also examines whether fake news concerns have led viewers to abandon specific channels, providing insight into potential economic impacts on news organizations.The study also explores viewers' perspectives on combating fake news, assessing the perceived importance of verifying news across multiple sources, interest in media literacy programs, and attitudes towards stricter regulations for news channels. By analyzing these aspects, the research aims to provide a comprehensive understanding of the fake news phenomenon in Hindi-language television news. The findings will offer valuable insights for news organizations, policymakers, and media literacy advocates, potentially informing strategies to enhance news credibility, combat misinformation, and restore viewer trust in an era of information overload and increasing media scepticism.
INDIGENOUS KNOWLEDGE SYSTEMS AND PRESERVATION OF EMBROIDERY CULTURE: CASE STUDIES ON LAMBANI EMBROIDERY IN INDIA
Authors: Sahu Bhawna , Tiwary Anuradha R.
Published: October 2024

The Lambani community is known for its rich and colorful embroidery. The community depends on this art form for their cultural expression. Lambani embroidery is an essential reservoir of historical information and cultural identity passed down through the ages. The research paper will explore the case studies of Lambani embroidery artisans and will examine the functions of Indigenous Knowledge Systems (IKS) in protecting cultural heritage. The paper will provide insight into how Indigenous knowledge, such as traditional symbols, practices, and skills passed down through the ages, is embodied and communicated through Lambani embroidery.On the other hand, lambani embroidery has become commercialized with time and has provided new economic opportunities, especially for women in the community. Commercialization comes with maintaining the craft's authenticity while meeting the consumers' demand. The paper will also shed light on the balance between adapting to modern market demands and preserving the traditional culture of Lambani embroidery. It also provides insights into strategies for supporting the sustainable development of traditional crafts while ensuring the continuity of indigenous knowledge. These case studies demonstrate how IKS may be successfully incorporated into modern cultural and economic frameworks while supporting sustainable development and the preservation of cultural heritage.
Digital solutions in the activities of small logistics enterprises (on the example of the Sverdlovsk region)
Authors: Vlasov Maxim V. , Sidorov Artem A.
Published: October 2024

Process digitalization is becoming such an important trend in logistics. The introduction of information technologies such as the Internet of Things, blockchain, sustainability technologies, robotization, big data analysis and artificial intelligence significantly allows to increase the efficiency of logistics companies, optimize routes and improve inventory management. However, at the level of small businesses, which play a key role in last-mile delivery, such technologies are practically not used due to their high cost and unclear payback prospects. Analysis has shown that digital solutions such as digital document management, digital signature, electronic reporting systems, monitoring and control systems, cargo search platforms and special applications are popular among microenterprises and individual entrepreneurs.
Resource constraints in implementing electronic document management systems
Authors: Plakhin Andrey E. , Ogorodnikova Ekaterina S. , Rostovtsev Konstantin V.
Published: October 2024

The relevance of the study of the level of implementation of electronic document management systems by Russian companies and the definition of resource constraints for the implementation of these systems is due to modern conditions characterized by significant restrictions on the activities of Russian business, including in the field of business process informatization. The research method uses the analysis of state statistics data on the provision of Russian enterprises with software and personnel in the IT field. The results of the study showed that the key resource limitations of the introduction of electronic document management systems are the need to compensate the costs of issuing EDS for all types of organizations, high costs of purchasing ready-made solutions for small and medium-sized businesses, the need to provide Internet access and purchase special equipment and expand the staff of IT specialists.
NEW LONG NON-CODING RNAS IN LUNG CANCER ONCOGENESIS
Authors: Podlesnaya P. , Kovaleva O. , Petrenko A. , Kushlinskii N. , Gratchev A.
Published: October 2024

This review is devoted to summarizing the available data on the expression of long non-coding RNAs (lncRNAs) in lung cancer cells and tissues, their role in tumorigenesis, association with clinical and morphological characteristics and disease prognosis. The purpose of this study is to search and describe new lncRNAs involved in the mechanisms of lung cancer progression. Material and methods. An analysis of scientific literature was carried out using the PubMed/Medline, RSCI/elibrary databases over the past 5 years. Results. Long non-coding RNAs are a promising tool for the diagnosis and treatment of cancer, including lung cancer. To date, a large number of lncRNAs have been described that are associated with lung cancer and/or involved in various mechanisms of disease progression. However, data on the role of each of them is fragmentary and further comprehensive studies of the functions of the identified lncRNAs in the pathogenesis of lung cancer are required.
USE OF MESENCHYMAL STEM CELLS IN COMPLEX TREATMENT OF DRUG-RESISTANT RENAL TUBERCULOSIS (EXPERIMENTAL STUDY WITH MORPHOLOGICAL CONTROL)
Authors: Vinogradova T. , Esmedlyayeva D. , Dyakova M. , Muravyev A. , Remezova A. , Ariel B. , Bogdanova E. , Dogonadze M. , Zabolotnykh N. , Yudintseva N. , Polyakova V. , Yablonskiy P.
Published: October 2024

Introduction. The use of mesenchymal stem cells (MSCs) is recognized as a promising direction for the treatment of diseases with a predominance of inflammation and sclerosis in the pathogenesis, which includes nephrotuberculosis (NT). Target. Studying the effectiveness of using MSCs in the complex treatment of experimental renal tuberculosis caused by a multidrug-resistant pathogen strain, and assessing the effect of cell therapy on the nature of reparative processes. Material and methods. NT with MDR was modeled in rabbits by inoculating the renal parenchyma cortex with a suspension of the clinical strain 5582 of Mycobacterium tuberculosis genotype Beijing (106 mycobacteria/0.2 ml). There were 3 groups: 1st (n=6) – infection control (infected, untreated); 2nd (n=7) – anti-tuberculosis therapy – ethambutol, bedaquiline, perchlozone, linezolid; 3rd main group (n=7) – rabbits 2 months after the start of chemotherapy were injected with a single suspension of 5×107 MSCs/2 ml PBS into the lateral vein of the ear. NT was confirmed by the results of Diaskintest® and computed tomography (CT), and the presence of viable MSCs by confocal microscopy with RKN-26 dye. A histological and morphometric study of the kidneys was carried out. We used the Statistica 7.0 package Results. The development of NT was confirmed by positive results of Diaskintest® and CT data (18 and 30 days after infection, respectively). 3 months after infection, only in group 1, foci of specific inflammation remained in the kidney tissue and pronounced glomerular changes were noted. In rabbits of the 3rd group, compared to the 2nd group, a low width of the medulla was revealed, as well as parameters of the area of interstitial fibrosis and collagen area, and higher values of glomerular cellularity. Conclusion. The participation of MSCs in complex therapy of NT led to a complete regression of specific inflammation in the kidney tissues, acceleration of reparative processes, and contributed to the preservation of the filtration capacity of the kidneys and the efficiency of urine excretion.
LOCAL PRODUCTION OF NEUROTROPHIC FACTORS UNDER THE INFLUENCE OF FRACTAL STIMULATION PHOTOTHERAPY ON THE RETINA OF RABBITS
Authors: Balatskaya N. , Fadeev D. , Zueva M. , Neroeva N.
Published: October 2024

Introduction. Recently, a new approach to visual response has been discussed, based on the use of optical signals of a heavy structure, manifested by fractal dynamics. However, the molecular mechanisms of action of fractal phototherapy (FF) have not been studied. Purpose of the study: to study the effect of low-intensity fractal optical stimulation on the intraocular production of neurotrophic cytokines in an in vivo experiment. Material and methods. The material for the study was the vitreous body (VH), isolated from the enucleated eyes of 17 healthy Soviet Chinchilla rabbits. 14 animals, depending on the duration of FF courses, were divided into five groups. 3 rabbits (6 eyes) made up the control group. In this work we used an original device for conducting FF in laboratory animals with two emitters. Photostimulation sessions were carried out daily. The duration of each FF session was 20 minutes. The duration of FF courses for different rabbits ranged from 7 to 180 days. Using enzyme immunoassay, the concentrations of 5 mediators were determined in vitreous samples: brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), interleukin(IL)-6, IL-1β and pigment epithelium dependent factor (PEDF). The results were recorded using a Cytation 5 multifunctional photometer. Results. BDNF and PEDF were detected in 100% of ST test samples of the main and control groups of animals. IL-1β and CNTF were absent in all biomaterial samples. In only one case, IL-6 was detected in a small concentration in the material from an experimental eye at late stages of FF. This work was the first to study the dynamics of intraocular production of neurotrophic factors under the influence of fractal photostimulation. Individual analysis demonstrated multidirectional changes in PEDF concentration (relative to normal levels) in the early stages of FF, namely: An increase in the intraocular content of this cytokine was observed in approximately 17% of experimental eyes after the 7th session, while the BDNF value was in the normal range. Conclusion. For the first time, local production of neurotrophic factors in intact eyes was studied. The features of the dynamics of neurotrophic factors depending on the duration of FF were studied. It has been shown that FF has stimulating activity (with an accumulative effect) on local BDNF production. The data obtained seem important for the development of the FF method and its translation into the clinic for visual rehabilitation of patients with neurodegenerative diseases of the retina and indicate the need for further research into the molecular mechanisms that realize the biological effects of FF.
PENGARUH KETERBUKAAN PERDAGANGAN, STABILITAS POLITIK, DAN PERTUMBUHAN EKONOMI TERHADAP ARUS MASUK FOREIGN DIRECT INVESMENT DI 10 NEGARA ASEAN TAHUN 2012 – 2022
Authors: Fatimah Siti , Salmah Emi , Ismiwati Baiq. , Sriningsih Siti , Sandya Sundus
Published: October 2024

Penelitian ini bertujuan untuk menganalisis pengaruh keterbukaan perdagangan, stabilitas politik, dan pertumbuhan ekonomi terhadap arus masuk Foreign Direct Investment (FDI) di 10 Negara ASEAN selama periode 2012-2022. Penelitian ini menggunakan data panel dari 10 negara ASEAN tahun 2012-2022, dengan mengaplikasikan tiga model berbeda. Fixed Effect (FEM) untuk klaster pertama yang dipilih melalui Uji Chow dan Uji Hausman,  regresi berganda untuk klaster kedua, dan Random Effect untuk klaster ketiga yang dipilih melalui Uji Chow, Uji Hausman, dan Uji Lagrange Multiplier. Pembagian klaster negara-negara dilakukan menggunakan metode K-means clustering. Hasil penelitian menunjukkan adanya perbedaan pengaruh ketiga variabel tersebut terhadap arus masuk FDI di setiap klaster negara. Klaster pertama, yang mencakup Indonesia, Myanmar, Filipina, dan Thailand, menunjukkan bahwa keterbukaan perdagangan dan stabilitas politik berpengaruh positif signifikan terhadap arus masuk FDI, sedangkan pertumbuhan ekonomi tidak signifikan. Klaster kedua, yang hanya mencakup Singapura, menunjukkan keterbukaan perdagangan dan stabilitas politik tidak signifikan, namun pertumbuhan ekonomi berpengaruh positif signifikan. Sementara itu, klaster ketiga, yang terdiri dari Malaysia, Brunei Darussalam, Kamboja, Vietnam, dan Laos,  menunjukkan bahwa keterbukaan perdagangan dan stabilitas politik berpengaruh negatif signifikan, sementara pertumbuhan ekonomi tidak signifikan. Hasil penelitian ini menyoroti perbedaan pengaruh faktor-faktor tersebut dalam menentukan arus masuk FDI di negara-negara ASEAN.
Evaluation of The Rationality of Hypertension Medication Use in Puskesmas Central Cimahi
Authors: Hermanto Faizal , Choirunissa Anna , Sutarna Titta Hartyana , Amelia Riza , Rizwan Akmal
Published: October 2024

A persistent and abnormal increase in blood pressure in the arteries is known as hypertension (HT. This research aims to assess the consumption of antihypertension at the Puskesmas Central Cimahi. Non-analytical descriptive methods were used in this investigation. Retrospective data was collected by accessing patient prescriptions and medical record data. Fifty-six patient samples in this study met the inclusion requirements. Quantitative and qualitative methods are used to evaluate rationality. Quantitative data analysis is processed to determine the number of patients, gender, age, and type of drug classification. Qualitative data analysis is processed to evaluate the appropiate of the indication, drug, patient and dose. Based on the research results, 52 people suffered from stage 1 hypertension, and four patients suffered from stage 2 hypertension. Amlodipine monotherapy was the most frequently prescribed drug, namely 92%. While the combination of amlodipine, captropil, amlodipine, and hydrochlorothiazide amounted to 4%. The rationality of treating hypertensive patients who meet the right indications, the right drug, the right patient and the right dose is 100%. It can be concluded that the evaluation and use of hypertension medication at the Puskesmas Central Cimahi as a whole meets the criteria for rational treatment.
Analisis Nilai Moral Dalam Novel Perempuan Dari Lembah Mutis Karya Meza E. Pollundou
Authors: Klobong Maria Selvia , Wissang Imelda Oliva , Lawet Pilipus Wai
Published: October 2024

ABSTRAK
Tujuan penenlitian ini untuk mendeskripsikan wujud dan fungsi nilai moral dalam novel Perempuan dari Lembah Mutis karya karya Mezra E. Pellondou. Teori yang digunakan adalah sosiologi sastra. Metode penelitian yang digunakan adalah deskriptif kualitatif. Berdasarkan hasil analisis data disimpulkan bahwa novel Perempuan dari Lembah Mutis karya karya Mezra E. Pellondou memiliki wujud dan fungsi nilai moral, (1) nilai moral hubungan manusia dengan diri sendiri. a) perjuangan tokoh utama dengan fungsi nilai moral b) Penghargaan terhadap diri, c) memiliki impian, d) pengembangan diri, e) ketekuan, f) keberanian, g) komitmen, h) kebahagiaan, dan i) penyesalan, (2) Nilai moral yang berhubungan dengan sesama manusia. a) empati, b) Kerja sama, c) kepeduliaan, d) penghargaan, e) Pemberdayaan, f) Penyesalan, dan g) Kesetiaan, (3) Nilai moral yang berhubungan dengan Tuhan. a) Rasa Syukur, b) Kepercayaan, c) Pengakuan akan kuasa Tuhan, d) Permohonan, dan e) Pengabdian, (4) Nilai moral yang berhubungan dengan lingkungan. a) Tanggung jawab, b) kesadaran, dan c) kepeduliaan.
Kata Kunci: nilai, moral, novel, sosiologi sastra.
 ABSTRACT
The purpose of this research is to describe the form and function of moral values in the novel Women from the Lembah Mutis by Mezra E. Pellondou. The theory used is literary sociology. The research method used is qualitative descriptive. Based on the results of data analysis, it was concluded that the novel Women from the Lembah Mutis by Mezra E. Pellondou has the form and function of moral values, (1) the moral value of human relationships with oneself. a) the struggle of the main character with the function of moral values b) Respect for oneself, c) having dreams, d) self-development, e) perseverance, f) courage, g) commitment, h) happiness, and i) regret, (2) moral values related to fellow human beings. a) empathy, b) cooperation, c) caring, d) appreciation, e) empowerment, f) regret, and g) loyalty, (3) moral values related to God. a) Gratitude, b) Trust, c) Recognition of God's power, d) Petition, and e) Service, (4) Moral values related to the environment. a) Responsibility, b) awareness, and c) care.
Keywords: values, morals, novels, literary sociology
The Development of Innovative Science Learning Tools to Develop 21st Century Skills for Elementary School Teachers Naskat II Santo Ignatius Olilit Timur
Authors: Leasa Marleny , Batlolona John Rafafy
Published: October 2024

The Tanimbar Islands are one of the areas in Maluku Province which is classified as an underdeveloped area in Indonesia and is included in the 3T category. This district borders directly with Australia. The underdevelopment of the Tanimbar Islands covers various sectors including education. The quality of teachers, availability of books, and other facilities and infrastructure are still very minimal. The results of observations and discussions with teachers at Naskat II Elementary School Santo Ignatius Olilit Timur showed that the development of devices is still less innovative because teachers do not participate in training that supports improving teacher competence in science learning in the classroom. Therefore, the purpose of this service is to increase the capacity of teachers in developing innovative learning devices to support 21st century life skills. Therefore, professional lecturers from the Faculty of Teacher Training and Education, Pattimura University, conducted training and mentoringin developing learning tools based on innovative learning.The results achieved from this activity mentoring are 86.28%teachers have been able to develop science learning tools well. Therefore, it is important for lecturers, Widyaiswara at the Education Quality Assurance Center (BPMP) in each province, school supervisors and education observers to continue to collaborate with teachers in sharing experiences and knowledge in improving teacher capacity
Increasing the Capacity of Teachers and Students in Understanding the Concept of Environmental Awareness of Honey Bee Cultivation
Authors: Papilaya Pamela Mercy , Lamerkabel Jacobus SA , Tuapattinaya Prelly MJ
Published: October 2024

Bees are honey-producing insects from the genus apis. In addition to honey, bees also produce pollen, royal jelly, propolis, beeswax and bee venom. Honey products that are widely found in Indonesia come from local honey bees, superior bees, wild bees, and lanceng bees. The high demand has driven up the price of honey bee products. Propolis has various health benefits such as containing high antioxidants and phenols, so it has the potential to cure various diseases such as toothache, influenza, diabetes mellitus, tuberculosis, and others. The purpose of this community service is to provide assistance to students regarding environmental awareness of honey bee cultivation at the Pattimura University Laboratory Middle School, Ambon and to increase the capacity of teachers in understanding the concept of environmental awareness of honey bee cultivation. The steps taken for learning honey bee cultivation use Project based learning (PjBL).
Preferência e satisfação pela via de parto de gestantes em um município paranaense
Authors: Reis Aryane dos , Krauss Liliane Alexandre , Rodrigues Raphaela Rezende Nogueira
Published: October 2024

Este estudo teve por objetivo avaliar a preferência da via de parto das gestantes que realizam o pré-natal e puerpério no serviço público de um município do sudoeste do Paraná, e a satisfação em relação ao parto realizado. É um estudo quantitativo descritivo e longitudinal com amostragem por conveniência. Foram inicialmente incluídas 89 gestantes entre 16 e 49 anos, das quais 72 participaram de entrevistas em duas etapas. Os resultados mostraram que 69,4% das participantes preferiram o parto vaginal e dos partos realizados, 54,1% foram vaginais. A maioria das participantes se mostrou satisfeita com a via de parto escolhida, tendo boa experiência em relação ao parto. O número de cesarianas excedeu o recomendado pela OMS. Compreender os fatores que levam à escolha da via de parto deve guiar a assistência à saúde, visando melhorar sua qualidade, respeitar a autonomia das gestantes e fornecer atendimento de qualidade, garantindo uma experiência positiva.
Especialidades médicas - Volume 1
Authors: Penna Letícia Machado Rodrigues , Koch Tammiress Braz , Roscoe Marcela Marçal , Camacho Sebastián Alonso Hernandez
Published: October 2024

Este livro aborda de forma clara e didática as principais especialidades médicas, oferecendo conteúdo atualizado para profissionais e estudantes. Explora áreas como cardiologia, neurologia e cirurgia, com ênfase na prática clínica e nos desafios atuais da medicina. Os capítulos combinam teoria e casos reais, proporcionando uma visão ampla e prática. Essencial para quem deseja aprofundar seus conhecimentos e se preparar para os desafios da profissão médica.
Workplace Romance: A Research on Flight Attendants in Aviation Industry
Authors: Çoban Ramazan , Mumlu Karanfil Seda
Published: October 2024

The aim of this research is to examine different aspects of workplace romance experienced by flight attendants in the aviation industry. Qualitative research method was used to examine the research subject in depth. The research was guided by using the phenomenology design, which is one of the qualitative research designs. The sample of the research was determined according to purposeful sampling and saturation point methods. In this context, the sample of the research consists of 11 flight attendants working in different airline companies in Turkey. Online interview method was used as a data collection tool. The data obtained was subjected to content analysis using MAXQDA 24 qualitative data analysis program with an inductive and descriptive approach. As a result of the content analysis, the research findings were collected under five themes. These themes include: factors affecting workplace romance, factors obstructing workplace romance, types of romantic relationships at workplace, results of workplace romance and management of workplace romance. According to the findings, the reasons why male and female employees have romantic relationships at work differ; It has been observed that different romantic relationships emerge depending on the position of the partners and the reasons for the relationship, and that workplace romance have positive and negative results individually/organizationally. It is thought that the research results will contribute to the literature on the concept of workplace romance and organizational behavior in the aviation industry.
Offline English Handwritten Character Recognition using Sequential Convolutional Neural Network
Authors: Iqbal Muhammad , Humayun Muniba , Siddiqi Raheel , Harrison Christopher J. , Malik Muneeb Abid
Published: October 2024

Handwritten Character recognition falls under the domain of image classification that has been under research for years. The idea is to make the machine recognize handwritten human characters. The language focused in this research paper is English while using offline handwritten character recognition for identifying English characters. There are many publically available datasets from which EMNIST is the most challenging one.  The main idea of this research paper is to propose a deep learning CNN method to help recognize English characters. This research paper proposes a deep learning convolutional neural network that is tested and compared with renowned pre-trained models using transfer learning. These parametric settings address multiple issues and are finalized after experimentation. The same hyper-parametric settings were used for all the models under test and E-Character with the same data augmentation settings. The proposed model named the E-Character recognizer was able to produce 87.31% accuracy. It was better than most of the tested pre-trained models and other proposed methods by other researchers. This research paper further highlighted some of the problems like misclassification due to the similar structure of characters.
Comparative Analysis of Pre-trained based CNN-RNN Deep Learning Models on Anomaly-5 Dataset for Action Recognition
Authors: Fayaz Ahmed Memon  , Umair Ali Khan  , Pardeep Kumar  , Halepoto Imtiaz Ali , Farida Memon
Published: October 2024

Action recognition in videos is one of the essential, challenging and active area of research in the field of computer vision that adopted in various applications including automated surveillance systems, security systems and human computer interaction. In this paper, we present an in-depth comparative analysis of five CNN-RNN models based on pre-trained networks such as InceptionV3, VGG16, MobileNetV2, ResNet152V2 and InceptionResNetV2 with recurrent LSTM units for action recognition on Anomaly-5 dataset. The performance of these models is analyzed and compared in terms of accuracy, precision, recall & F1-scores and computational efficiency. The CNN-RNN architectures we considered for analysis in this paper, the ResNet152V2 based CNN-RNN model exhibits better performance and achieved highest accuracy, precision, recall and F1-score equal to 92.20% due to its ability to capture more complex spatial features. This comparative analysis may guide the researchers in selecting appropriate models for real-world applications for action recognition. In addition of this, a new dataset is developed called Anomaly-5 that can helps as a valuable resource for training and evaluating action recognition algorithms.
Medicinal Benefits of Ganoderma lucidum (Reishi) in Cancer Treatment: A review of current evidence and future directions
Authors: Sunidhi Kachari
Published: October 2024

In the ancient practice of Asian medicine, Ganoderma lucidum popularly known as Reishi or Lingzhi, has assumed enormous respect for its potential health benefits. In the past years, however, more studies have focused on its anticancer effects specifically due to its bioactive components including triterpenes, polysaccharides, and proteins. This article reviews the properties and mechanisms of various active compounds in G. lucidum against cancer. Strong anticancer effects typical of triterpenes are gained by promoting cell apoptosis and suppressing tumor metastasis by ganoderic acids. Most polysaccharides enhance immune response and possess anti-tumor activity while proteins such as Ling Zhi-8 have immuno-modulatory effects. Out of the nature of research and some clinical data, most researches to date include small samples and short durations. Efforts geared towards the assessment show the need to carry out more precise thorough clinical studies in order to establish the various benefits and risks of G. lucidum as a cancer treatment method. At this time, it is likely that G. lucidum will be used to augment such treatment however there should be more fundamental evidence to support this claim towards improvement or even substitution of such therapy without compromising efficacy and safety measures of G. lucidum.
Opioid antagonist Utilization Patterns in United States Emergency Department Visit: A Retrospective Study
Authors: Ateequr Rahman  , Zabrina Abolarin  , Gabriella Schmit  , Aman Patel  , Anwar Oshana  , Sara Rahman  , Lejla Cukovic
Published: October 2024

Background: The aim of this study was to determine if emergency department (ED) visits due to opioid overdose are affected by patient demographics, geographic location, and type of insurance used for payment. Methods: The type of opioid reversal agent used in the ED was assessed, including patient age, ethnicity, gender, insurance payer, and geographical region of the United States. Results: Patients from the South (48.8%), above 50 years old (44.1%), and the White population (44.9%) had the greatest number of opioid overdose vases versus their comparable demographics. There was a statistically significant difference amongst various regions included in, with the South having the largest number of patients receiving opioid reversal agents (p = 0.001). There was a statistically significant difference between various payment forms, with most patients of both genders paying out-of-pocket (p = 0.003). There were no significant differences between male and female patients in terms of which antidote was received (p = 0.595). Conclusions: Policy and healthcare changes are necessary to prevent intentional opioid overdose and its etiology.
Association between diabetes and depression: A narrative review
Authors: Abimanyu Muthuraman  , Gowtham Prabhu  , Srinivas G  , Jasmine S Sundar  , Kalpana S  , Valarmathi S
Published: October 2024

Background: A major global health concern, diabetes mellitus affects 422 million people worldwide, with a higher prevalence in low- and middle-income nations. At almost 74 million diagnosed cases, India comes in second. Incidences as grave as neuropathy and cardiovascular disease are associated with the increasing frequency. Comorbid depression is a serious but largely disregarded problem that affects up to 38% of people in India who have type 2 diabetes and has a substantial negative influence on quality of life. Social and clinical factors such as age, gender, and glycemic control influence the association between diabetes and depression. Inflammatory reactions and lifestyle decisions also play a role in this link. For better health results, this co-occurrence must be addressed. Tailored therapies are needed as the burden of both illnesses increases, especially in developing nations. Methods: A Comprehensive literature search was conducted, which were sourced google scholar, PubMed, WHO website, international diabetes federation. Conclusion: Diabetes and depression have a significant and complex relationship that affects millions of people worldwide, but particularly in places like India. Diabetes and depression frequently coexist, and the course of each condition is adversely affected by the other. Since each disorder appears to function in longitudinal research as both a risk factor and a consequence for the other, the direction of causality is unclear. diabetes is becoming a more widespread public health concern, improving the quality of life and general well-being of this group will depend on recognizing and treating the co-occurrence of depression. For data to inform best practices in healthcare delivery, future research should concentrate on creating tailored interventions and comprehending the complex dynamics of this crucial link.
Innovative biotechnological approaches for plastic degradation: A pathway to sustainable waste management
Authors: Akash Phillip  , Tushar Chauhan
Published: October 2024

Plastic pollution has escalated into a global environmental crisis, with millions of tons of synthetic polymers accumulating within ecosystems and posing significant threats to both biodiversity and human health. Conventional methods of plastic waste management, such as mechanical and chemical recycling, exhibit limitations in terms of sustainability, particularly for polymers such as polyethylene (PE) and polystyrene (PS), which demonstrate a pronounced resistance to degradation. Biotechnological approaches that exploit microbial enzymes and synthetic biology offer a promising alternative to tackle this pressing issue. Enzymes such as PETase and MHETase, which facilitate the degradation of polyethylene terephthalate (PET), in conjunction with laccases and lipases that target more recalcitrant plastics, have manifested considerable potential in deconstructing plastics at the molecular level. Notwithstanding these advancements, challenges persist regarding degradation efficiency, especially for non-PET plastics, as well as the economic viability of scaling these biotechnological processes. Furthermore, environmental parameters including temperature, pH, and oxygen levels significantly influence enzyme functionality, while regulatory and societal obstacles impede the utilization of genetically modified organisms (GMOs). Nevertheless, emerging technologies such as protein engineering, CRISPR-based gene editing, and industrial applications like bioreactors present avenues for surmounting these challenges. This article investigates the current landscape, challenges, and prospects associated with biotechnological plastic degradation, emphasizing its potential contribution to achieving global circular economy objectives and enhancing sustainable waste management strategies.