bluuebunny/crossref_metadata_2025 huggingface dataset:
A Novel Locality Algorithm and Peer-to-Peer Communication Infrastructure for Optimizing Network Performance in Smart Microgrids
Authors: Marzal Silvia , González-Medina Raul , Salas-Puente Robert , Figueres Emilio , Garcerá Gabriel
Published: August 2017

Peer-to-Peer (P2P) overlay communications networks have emerged as a new paradigm for implementing distributed services in microgrids due to their potential benefits: they are robust, scalable, fault-tolerant, and they can route messages even when a large number of nodes are frequently entering or leaving the network. However, current P2P systems have been mainly developed for file sharing or cycle sharing applications where the processes of searching and managing resources are not optimized. Locality algorithms have gained a lot of attention due to their potential to provide an optimized path to groups with similar interests for routing messages in order to achieve better network performance. This paper develops a fully functional decentralized communication architecture with a new P2P locality algorithm and a specific protocol for monitoring and control of microgrids. Experimental results show that the proposed locality algorithm reduces the number of lookup messages and the lookup delay time. Moreover, the proposed communication architecture heavily depends of the lookup used algorithm as well as the placement of the communication layers within the architecture. Experimental results will show that the proposed techniques meet the network requirements of smart microgrids, even with a large number of nodes on stream.
Control Structures Evaluation for a Salt Extractive Distillation Pilot Plant: Application to Bio-Ethanol Dehydration
Authors: Cantero Carlos , Lopez Guadalupe , Alvarado Victor , Jimenez Ricardo , Morales Jesse , Coronado Eduardo
Published: August 2017

This paper addresses the challenge of evaluating control structures for a salt extractive distillation column producing absolute ethanol for use as biofuel. A sensitivity analysis aided with designing a pseudo-binary distillation pilot plant and examining the conceived process and the influence of the reflux ratio on both product purity and energy consumption. We compare three control structures for inferential tracking of the distillate composition: a dual-temperature control with an RV (reflux/boilup) structure and two single-end temperature control configurations, and their performance is measured using deterministic indicators. The result is the proposal of a pilot plant design for treating 15 kg/h of a diluted mixture with mole fraction of ethanol equal to 0.2 and assuming a column efficiency of 50%. The R/F (reflux to feed ratio) configuration is the best control structure, given that its corresponding performance indicators conduct lowest steady-state errors, less oscillating responses, and reduced settling times. For this configuration, the reflux flow rate is rationed to the feed flow rate, and the temperature is controlled manipulating the distillate flow rate. Even subject to perturbations, the energy consumption of the plant remains close to the nominal value. The three evaluated control structures consistently met international quality standards for fuel ethanol and enhanced the use of salts in ethanol dehydration.
Recovery of Low Permeability Reservoirs Considering Well Shut-Ins and Surfactant Additivities
Authors: Li Shuai , Tang Jun , Ding Yunhong , Liu Shimin , Liu Guangfeng , Cai Bo
Published: August 2017

To investigate the mechanism whereby well shut-ins and surfactant additivities can increase hydrocarbon output after hydraulic fracturing, in this paper, we simulated well shut-ins with one end open (OEO) rock samples and performed a serious of imbibition experiments with different surfactant additivities based on contact angle (CA) and interfacial tension (IFT) measurements. Scanning electron microscope (SEM) and nuclear magnetic resonance (NMR) methods were also been adopted in the detection before and after shut-ins. The results demonstrated that cationic surfactants result in better improving oil recovery (IOR) performance due to their high wettability alteration ability on vertical fracture faces, while different kinds of surfactants have a similar ability in lowering IFT. As for shut-ins duration, the NMR transverse relaxation time (T2) spectrum move towards the left side, indicating that aqueous phases migrate to smaller pores spaces and deeper distances. Aqueous migration during the shut-ins period can remove near-fracture trapped water, while surfactant additivities can accelerate and enhance this process, and these two points are the most direct reasons for the observed hydrocarbon output increases.
The Impact of Horizontal Resolution on Energy Transfers in Global Ocean Models
Authors: Kjellsson Joakim , Zanna Laure
Published: August 2017

The ocean is a turbulent fluid with processes acting on a variety of spatio-temporal scales. The estimates of energy fluxes between length scales allows us to understand how the mean flow is maintained as well as how mesoscale eddies are formed and dissipated. Here, we quantify the kinetic energy budget in a suite of realistic global ocean models, with varying horizontal resolution and horizontal viscosity. We show that eddy-permitting ocean models have weaker kinetic energy cascades than eddy-resolving models due to discrepancies in the effect of wind forcing, horizontal viscosity, potential to kinetic energy conversion, and nonlinear interactions on the kinetic energy (KE) budget. However, the change in eddy kinetic energy between the eddy-permitting and the eddy-resolving model is not enough to noticeably change the scale where the inverse cascade arrests or the Rhines scale. In addition, we show that the mechanism by which baroclinic flows organise into barotropic flows is weaker at lower resolution, resulting in a more baroclinic flow. Hence, the horizontal resolution impacts the vertical structure of the simulated flow. Our results suggest that the effect of mesoscale eddies can be parameterised by enhancing the potential to kinetic energy conversion, i.e., the horizontal pressure gradients, or enhancing the inverse cascade of kinetic energy.
The Collaborative Payer Provider Model Enhances Primary Care, Producing Triple Aim Plus One Outcomes: A Cohort Study
Authors: Doerr Thomas , Olsen Lisa , Zimmerman Deborah
Published: August 2017

Rising health care costs are threatening the fiscal solvency of patients, employers, payers, and governments. The Collaborative Payer Provider Model (CPPM) addresses this challenge by reinventing the role of the payer into a full-service collaborative ally of the physician. From 2010 through 2014, a Medicare Advantage plan prospectively deployed the CPPM, averaging 30,561 members with costs that were 73.6% of fee-for-service (FFS) Medicare (p < 0.001). The health plan was not part of an integrated delivery system. After allocating $80 per member per month (PMPM) for primary care costs, the health plan had medical cost ratios averaging 75.1% before surplus distribution. Member benefits were the best in the market. The health plan was rated 4.5 Stars by the Centers for Medicare and Medicaid Services for years 1–4, and 5 Stars in study year 5 for quality, patient experience, access to care, and care process metrics. Primary care and specialist satisfaction were significantly better than national benchmarks. Savings resulted from shifts in spending from inpatient to outpatient settings, and from specialists to primary care physicians when appropriate. The CPPM is a scalable model that enables a win-win-win system for patients, providers, and payers.
Assessing Knowledge and Attitudes towards Cervical Cancer Screening among Rural Women in Eastern China
Authors: Liu Tongtong , Li Shunping , Ratcliffe Julie , Chen Gang
Published: August 2017

There is a heavy burden of cervical cancer in China. Although the Chinese government provides free cervical cancer screening for rural women aged 35 to 59 years, the screening rate remains low even in the more developed regions of eastern China. This study aimed to assess knowledge and attitudes about cervical cancer and its screening among rural women aged 30 to 65 years in eastern China. A cross-sectional study was conducted in four counties of Jining Prefecture in Shandong Province during August 2015. In total, 420 rural women were randomly recruited. Each woman participated in a face-to-face interview in which a questionnaire was administered by a trained interviewer. A total of 405 rural women (mean age 49 years old) were included in the final study. Among them, 210 (51.9%) participants had high knowledge levels. An overwhelming majority, 389 (96.0%) expressed positive attitudes, whilst only 258 (63.7%) had undergone screening for cervical cancer. Related knowledge was higher amongst the screened group relative to the unscreened group. Age, education and income were significantly associated with a higher knowledge level. Education was the only significant factor associated with a positive attitude. In addition, women who were older, or who had received a formal education were more likely to participate in cervical cancer screening. The knowledge of cervical cancer among rural women in eastern China was found to be poor, and the screening uptake was not high albeit a free cervical cancer screening program was provided. Government led initiatives to improve public awareness, knowledge, and participation in cervical cancer screening programs would likely be highly beneficial in reducing cervical cancer incidence and mortality for rural women.
Responses of Biogeochemical Characteristics and Enzyme Activities in Sediment to Climate Warming under a Simulation Experiment in Geographically Isolated Wetlands of the Hulunbuir Grassland, China
Authors: Han Liliang , Su Derong , Lv Shihai , Luo Yan , Li Xingfu , Jiao Jian , Diao Zhaoyan , Bu He
Published: August 2017

Climate warming generates a tremendous threat to the stability of geographically-isolated wetland (GIW) ecosystems and changes the type of evaporation and atmospheric precipitation in a region. The intrinsic balance of biogeochemical processes and enzyme activity in GIWs may be altered as well. In this paper, we sampled three types of GIWs exhibiting different kinds of flooding periods. With the participation of real-time temperature regulation measures, we assembled a computer-mediated wetland warming micro-system in June 2016 to simulate climate situation of ambient temperature (control group) and two experimental temperature differences (+2.5 °C and +5.0 °C) following a scientific climate change circumstance based on daily and monthly temperature monitoring at a two-minutes scale. Our results demonstrate that the contents of the total organic carbon (TOC), total nitrogen (TN), and total phosphorus (TP) in the warmed showed, roughly, a balance or a slight decrease than the control treatment. Warming obstructed the natural subsidence of sediment, but reinforced the character of the ecological source, and reduced the activity of urease (URE), but promoted the activity of alkaline phosphatase (AKP) and sucrase (SUC). Redundancy analysis showed that sucrase, urease, available phosphorus (AP), and pH were the major correlating factors under warming conditions in our research scope. Total organic carbon, total nitrogen, sucrase, catalase (CAT), and alkaline phosphatase were the principal reference factors to reflect the ambient temperature variations. Nutrient compositions and enzyme activities in GIW ecosystems could be reconstructed under the warming influence.
Determination of Selected Chemical Levels in Room Air and on Surfaces after the Use of Cartridge- and Tank-Based E-Vapor Products or Conventional Cigarettes
Authors: Liu Jianmin , Liang Qiwei , Oldham Michael , Rostami Ali , Wagner Karl , Gillman I. , Patel Piyush , Savioz Rebecca , Sarkar Mohamadi
Published: August 2017

There is an ongoing debate regarding the potential of secondhand exposure of non-users to various chemicals from use of e-vapor products (EVPs). Room air levels of 34 chemicals (nicotine, propylene glycol (PG), glycerol, 15 carbonyl chemicals, 12 volatile organic chemicals (VOCs), and four selected trace elements) were measured where EVPs and cigarettes were used by n = 37 healthy adult tobacco users in an exposure chamber. The products used were MarkTen® 2.5% Classic (Group I), a Prototype GreenSmoke® 2.4% (Group II), Ego-T® Tank with subjects’ own e-liquids (Group III) and subjects’ own conventional cigarettes (Group IV). Products were used under controlled conditions and 4-h ad libitum use. Background (without subjects) and baseline levels (with subjects) were measured. Cumulative 4-h. levels of nicotine, PG and glycerol measured were several-fold below the time-weighted average limits used in workplace exposure evaluation. Most the other chemicals (>75%) were at or below the limit of quantification during EVP use. Significant levels of chemicals (17 out of 34) were observed in Group IV. Overall, our results indicate that under the study conditions with the products tested, cumulative room air levels of the selected chemicals measured over 4-h were relatively small and were several-fold below the current occupational regulatory and consensus limits.
Occurrence, Distribution, and Risk Assessment of Perfluoroalkyl Acids (PFAAs) in Muscle and Liver of Cattle in Xinjiang, China
Authors: Wang Gehui , Lu Jianjiang , Xing Zhenni , Li Shanman , Liu Zilong , Tong Yanbin
Published: August 2017

Despite risks associated with perfluoroalkyl acids (PFAAs) in many regions, little is known about their prevalence in Xinjiang. We determined the presence of 13 PFAAs in 293 beef muscle and liver samples collected in 22 cities covering northern, southern, and eastern Xinjiang using liquid chromatography, coupled with tandem mass spectrometry. Overall, the average values for PFAAs were relatively low compared with previous studies. Liver presented higher mean levels of total PFAAs at 1.632 ng/g, which was over 60-fold higher than in muscle (0.026 ng/g). Among the PFAAs analyzed, medium-chain compounds were dominant, accounting for more than 70% of the total. Perfluorooctane sulfonate (PFOS) was highly prevalent in the liver with the highest mean concentration (0.617 ng/g) and detection frequency (80%). When comparing the three regions of Xinjiang, we found differences in PFAA profiles, with the northern region showing the highest levels. Furthermore, the average daily intake and hazard ratios of PFOS and perfluorooctanoic acid varied by region, urban/rural environment, gender, ethnicity, and age. The highest risk value of 13 PFAAs was estimated to be 0.837 × 10−3, which is far below 1, indicating that there is no health risk posed by eating beef muscle and liver in Xinjiang.
Surveillance Bias in Child Maltreatment: A Tempest in a Teapot
Authors: Drake Brett , Jonson-Reid Melissa , Kim Hyunil
Published: August 2017

Background: Children are believed to be more likely to be reported for maltreatment while they are working with mental health or social service professionals. This “surveillance bias” has been claimed to inflate reporting by fifty percent or more, and has been used to explain why interventions such as home visiting fail to reduce official maltreatment reporting rates. Methods: We use national child abuse reporting data (n = 825,763), supplemented by more detailed regional data from a multi-agency administrative data study (n = 7185). We determine the percentage of all re-reports made uniquely by mental health and social service providers within and across generations, the report sources which could be subject to surveillance bias. Results: At three years after the initial Child protective services (CPS) report, the total percentage of national reports uniquely made by mental health or social service providers is less than 10%, making it impossible that surveillance bias could massively inflate CPS reporting in this sample. Analysis of national data find evidence of a very small (+4.54%) initial surveillance bias “bump” among served cases which decays to +1.84% within three years. Our analysis of regional data showed similar or weaker effects. Conclusions: Surveillance bias effects appear to exist, but are very small.
The Mediating Role of Psychological Capital on the Association between Occupational Stress and Job Satisfaction among Township Cadres in a Specific Province of China: A Cross-Sectional Study
Authors: Shang Guan Chang-Yue , Li Yu , Ma Hong-Lin
Published: August 2017

Background: Township cadres, considered as basic executors of state policy, play an important role in Chinese society. Their job satisfaction is a vital issue for township management, but there are few studies on this topic in China. The goal of this study is to analyze the relationship between occupational stress and job satisfaction, and to further examine whether psychological capital (PsyCap) can serve as a mediator between stress and job satisfaction in Chinese township cadres. Methods: A cross-sectional survey was carried out during the period of from October 2015 to January 2016 in Liaoning Province of China. The questionnaires, which consisted of an effort-reward imbalance scale, Minnesota Satisfaction Questionnaire (MSQ) for job satisfaction, and the psychological capital questionnaire (PCQ-24), as well as questions about demographic characteristics, were distributed to 1800 township cadres and complete responses were received from 1525 participants. Structural equation modeling was used to examine the role that psychological capital played in mediating between occupational stress and job satisfaction. Results: In the present study, effort-reward ratio (ERR= 11 × effort/6 × reward) was negatively associated with job satisfaction (r = −0.372, p < 0.001), whereas psychological capital was positively associated with job satisfaction in township cadres (r = 0.587, p < 0.001) from a specific province in China. Psychological capital is a mediator between the association of job stress and job satisfaction. Conclusions: Psychological capital partially mediated the relationship between job stress and job satisfaction among Chinese township cadres. Interventions to improve Chinese township cadres’ job satisfaction should be developed in the future, especially the enhancement of PsyCap. Interventions need to be verified in further cohort studies. At present, we are only proposing a theoretical model. Intervention effects need to be validated in further cohort studies.
Tensions in Rural Water Governance: The Elusive Functioning of Rural Water Points in Tanzania
Authors: Katomero Jesper , Georgiadou Yola , Lungo Juma , Hoppe Robert
Published: August 2017

Public water services are still failing rural Tanzanians. Emboldened by advances in information communication technologies, the Ministry of Water has been developing computing, financial and administrative technologies to update and visualise the status of rural water points. This amalgam of technologies marks the emergence of an information infrastructure for rural water governance. The information infrastructure will enable the ministry to “see” the functionality status of all rural water points and to plan and budget for their repair and maintenance. In this paper, we examine three administrative technologies, which aim to standardise the functionality status of water points, and to prescribe how the information flows within the government hierarchy, and who is a legitimate recipient of this information. We analyze qualitative data, collected over a period of four years, in the framework of an interdisciplinary research program, funded by the Netherlands Organisation for Scientific Research—Science for Global Development (NWO-Wotro). In contrast to other researchers who study how information infrastructure evolves over time, we study what infrastructure evolution reveals about water governance. Our analysis of the practices of participants in rural water governance reveals tensions between formal and informal processes, which affect rural water services negatively.
The Emerging Role of GLP-1 Receptors in DNA Repair: Implications in Neurological Disorders
Authors: Yang Jenq-Lin , Chen Wei-Yu , Chen Shang-Der
Published: August 2017

Glucagon-like peptide-1 (GLP-1) is originally found as a metabolic hormone (incretin) that is able to regulate blood-glucose levels via promoting synthesis and secretion of insulin. GLP-1 and many analogues are approved for treatment of type II diabetes. Accumulating results imply that GLP-1 performs multiple functions in various tissues and organs beyond regulation of blood-glucose. The neuroprotective function of GLP-1 has been extensively explored during the past two decades. Three of our previous studies have shown that apurinic/apyrimidinic endonuclease 1 (APE1) is the only protein of the base excision repair (BER) pathway able to be regulated by oxidative stress or exogenous stimulations in rat primary cortical neurons. In this article, we review the role of APE1 in neurodegenerative diseases and its relationship to neuroprotective mechanisms of the activated GLP-1 receptor (GLP-1R) in neurodegenerative disorders. The purpose of this article is to provide new insight, from the aspect of DNA damage and repair, for studying potential treatments in neurodegenerative diseases.
Human Meibum Age, Lipid–Lipid Interactions and Lipid Saturation in Meibum from Infants
Authors: Sledge Samiyyah , Henry Collin , Borchman Douglas , Yappert Marta , Bhola Rahul , Ramasubramanian Aparna , Blackburn Ryan , Austin Jonathan , Massey Kayla , Sayied Shanzeh , Williams Aliza , Georgiev Georgi , Schikler Kenneth
Published: August 2017

Tear stability decreases with increasing age and the same signs of instability are exacerbated with dry eye. Meibum lipid compositional changes with age provide insights into the biomolecules responsible for tear film instability. Meibum was collected from 69 normal donors ranging in age from 0.6 to 68 years of age. Infrared spectroscopy was used to measure meibum lipid phase transition parameters. Nuclear magnetic resonance spectroscopy was used to measure lipid saturation. Increasing human meibum lipid hydrocarbon chain unsaturation with age was related to a decrease in hydrocarbon chain order, cooperativity, and in the phase transition temperature. The change in these parameters was most dramatic between 1 and 20 years of age. Meibum was catalytically saturated to determine the effect of saturation on meibum lipid phase transition parameters. Hydrocarbon chain saturation was directly related to lipid order, phase transition temperature, cooperativity, changes in enthalpy and entropy, and could account for the changes in the lipid phase transition parameters observed with age. Unsaturation could contribute to decreased tear film stability with age.
Multimodality Imaging in Tumor Angiogenesis: Present Status and Perspectives
Authors: Niccoli Asabella Artor , Di Palo Alessandra , Altini Corinna , Ferrari Cristina , Rubini Giuseppe
Published: August 2017

Angiogenesis is a complex biological process that plays a central role in progression of tumor growth and metastasis. It led to a search for antiangiogenic molecules, and to design antiangiogenic strategies for cancer treatment. Noninvasive molecular imaging, such as positron emission tomography (PET) and single photon emission computed tomography (SPECT), could be useful for lesion detection, to select patients likely to respond to antiangiogenic therapies, to confirm successful targeting, and dose optimization. Additionally, nuclear imaging techniques could also aid in the development of new angiogenesis-targeted drugs and their validation. Angiogenesis imaging can be categorized as targeted at three major cell types: (I) non-endothelial cell targets, (II) endothelial cell targets, and (III) extracellular matrix proteins and matrix proteases. Even if radiopharmaceuticals studying the metabolism and hypoxia can be also used for the study of angiogenesis, many of the agents used in nuclear imaging for this purpose are yet to be investigated. The purpose of this review is to describe the role of molecular imaging in tumor angiogenesis, highlighting the advances in this field.
Edge Detection Method Based on General Type-2 Fuzzy Logic Applied to Color Images
Authors: Gonzalez Claudia , Melin Patricia , Castillo Oscar
Published: August 2017

This paper presents a new general type-2 fuzzy logic method for edge detection applied to color format images. The proposed algorithm combines the methodology based on the image gradients and general type-2 fuzzy logic theory to provide a powerful edge detection method. General type-2 fuzzy inference systems are approximated using the α-planes approach. The edge detection method is tested on a database of color images with the idea of illustrating the advantage of applying the fuzzy edge detection approach on color images against grayscale format images, and also when the images are corrupted by noise. This paper compares the proposed method based on general type-2 fuzzy logic with other edge detection algorithms, such as ones based on type-1 and interval type-2 fuzzy systems. Simulation results show that edge detection based on a general type-2 fuzzy system outperforms the other methods because of its ability to handle the intrinsic uncertainty in this problem.
Sampling and Estimation of Pairwise Similarity in Spatio-Temporal Data Based on Neural Networks
Authors: Frey Steffen
Published: August 2017

Increasingly fast computing systems for simulations and high-accuracy measurement techniques drive the generation of time-dependent volumetric data sets with high resolution in both time and space. To gain insights from this spatio-temporal data, the computation and direct visualization of pairwise distances between time steps not only supports interactive user exploration, but also drives automatic analysis techniques like the generation of a meaningful static overview visualization, the identification of rare events, or the visual analysis of recurrent processes. However, the computation of pairwise differences between all time steps is prohibitively expensive for large-scale data not only due to the significant cost of computing expressive distance between high-resolution spatial data, but in particular owing to the large number of distance computations ( O ( | T | 2 ) ) , with | T | being the number of time steps). Addressing this issue, we present and evaluate different strategies for the progressive computation of similarity information in a time series, as well as an approach for estimating distance information that has not been determined so far. In particular, we investigate and analyze the utility of using neural networks for estimating pairwise distances. On this basis, our approach automatically determines the sampling strategy yielding the best result in combination with trained networks for estimation. We evaluate our approach with a variety of time-dependent 2D and 3D data from simulations and measurements as well as artificially generated data, and compare it against an alternative technique. Finally, we discuss prospects and limitations, and discuss different directions for improvement in future work.
Effect of Load Changes on Hybrid Shipboard Power Systems and Energy Storage as a Potential Solution: A Review
Authors: Shagar Viknash , Jayasinghe Shantha , Enshaei Hossein
Published: August 2017

More electric technologies (METs) play an important role in meeting ever-growing demands for energy efficiency and emission reduction in the maritime transportation sector. As a result, ships with electrical power transmission are becoming popular compared to traditional mechanical power transmission based ships. Hybrid electric propulsion is an intermediate step in this trend where both mechanical and electrical propulsion technologies are combined to get the benefits of both technologies. In this arrangement, not only the propulsion loads but also non-propulsion loads are connected to a common electrical power bus that could lead to serious power quality issues due to disturbances such as large load changes. This paper presents a comprehensive review on energy storage-based solutions that have been proposed to reduce their effects. The important aspects of existing as well as emerging energy storage control techniques and challenges in reducing transient effects in hybrid shipboard power systems with the use of energy storage are discussed in the paper.
Understanding Acoustic Emission for Different Metal Cutting Machinery and Operations
Authors: Nikhare Chetan , Conklin Chris , Loker David
Published: August 2017

Machining is one of the major manufacturing techniques where the material is removed to prepare the complete or sub-part. In general, this is also referred to as subtractive manufacturing. Due to solid-to-solid contact between the cutting tool and the work-piece, the machine dynamics get influenced by various operating parameters. This generates force and vibration, and thus noise. Over time the cutting tool reaches its end-of-life which increases the force to cut, and thus produces more vibration and noise. The noise parameter was considered in this work. A 32-element spherical microphone array acoustic camera system was used to record and analyze the sound that was emitted during the machining processes. The startup, idle, and load operating characteristics for various industrial machining equipment were monitored with the acoustic beam former microphone system. The industrial applications included a bench grinder, surface grinder, vertical band saw, lathe machine, and vertical milling machine. Analysis of the acoustic noise generated from these processes could demonstrate the similarities between the cyclical patterns of resonating sound.
“Language Is the Place from Where the World Is Seen”—On the Gender of Trees, Fruit Trees and Edible Fruits in Portuguese and in Other Latin-Derived Languages
Authors: Dias Luís , Dias Alexandra
Published: August 2017

Trees have always been important as natural entities carrying a strong symbolic and metaphorical weight, not to mention their practical uses. Therefore, words and their gender, used to name natural entities as important as trees and particularly fruit-trees and their fruits, are also important. Starting from the finding that Portuguese and Mirandese, the second official spoken language of Portugal, are Latin-derived languages in which ‘tree’ has feminine gender like it had in Latin, we investigated (1) the gender of ‘tree’ in Portuguese from the 10th to the 17th centuries sampling legal, literary, historical, scholar (mostly grammars and dictionaries), and religious manuscripts or printed sources; (2) the presumed variation in the gender of ‘tree’ during a short period in the 16th and 17th century; (3) the likely causes for that variation, which we found to be mostly due to typographic constraints and to compositors’ errors; (4) the gender distribution of fruit trees and fruits produced by fruit trees in Latin and in twelve Latin-derived languages. Portuguese, together with the intimately related Mirandese and Barranquenho, forms a cluster distinct from all other Latin-derived languages in its use of the feminine in the names of fruit trees and fruits, and in the gender agreement between them.
Achieving Independent Language Learning through the Mobilization of Ubiquitous Instructional Technology Resources
Authors: Burston Jack , Athanasiou Androulla , Yiokari-Neophytou Maro
Published: August 2017

In programs meant for foreign language majors, there is typically a broad range of linguistic competence in advanced-level Languages for Specific Purposes (LSP) courses. Troublesome in any course, this is especially so when instruction directly relates to professional training, where students need to attain a level of competence that will allow them to subsequently function as fully independent language learners. Considering the normal constraints on in-class instruction, the mobilization of ubiquitous instructional technology resources, coupled with sound curriculum design and metacognitive awareness raising, is critical to providing the amount of time on task required to attain this objective. The case of the English for Specific Academic Purposes course that is the subject of this study provides an example of how the challenge of bringing students up to the level of independent language learners has been approached. It is hoped this may serve as a pedagogical model that can be applied to advanced-level LSP courses in general.
Enhanced Azo-Dyes Degradation Performance of Fe-Si-B-P Nanoporous Architecture
Authors: Weng Nan , Wang Feng , Qin Fengxiang , Tang Wanying , Dan Zhenhua
Published: August 2017

Nanoporous structures were fabricated from Fe76Si9B10P5 amorphous alloy annealed at 773 K by dealloying in 0.05 M H2SO4 solution, as a result of preferential dissolution of α-Fe grains in form of the micro-coupling cells between α-Fe and cathodic residual phases. Nanoporous Fe-Si-B-P powders exhibit much better degradation performance to methyl orange and direct blue azo dyes compared with gas-atomized Fe76Si9B10P5 amorphous powders and commercial Fe powders. The degradation reaction rate constants of nanoporous powders are almost one order higher than those of the amorphous counterpart powders and Fe powders, accompanying with lower activation energies of 19.5 and 26.8 kJ mol−1 for the degradation reactions of methyl orange and direct blue azo dyes, respectively. The large surface area of the nanoporous structure, and the existence of metalloids as well as residual amorphous phase with high catalytic activity are responsible for the enhanced azo-dyes degradation performance of the nanoporous Fe-Si-B-P powders.
Review on Molecular Mechanisms of Antifouling Compounds: An Update since 2012
Authors: Chen Lianguo , Qian Pei-Yuan
Published: August 2017

Better understanding of the mechanisms of antifouling compounds is recognized to be of high value in establishing sensitive biomarkers, allowing the targeted optimization of antifouling compounds and guaranteeing environmental safety. Despite vigorous efforts to find new antifouling compounds, information about the mechanisms of antifouling is still scarce. This review summarizes the progress into understanding the molecular mechanisms underlying antifouling activity since 2012. Non-toxic mechanisms aimed at specific targets, including inhibitors of transmembrane transport, quorum sensing inhibitors, neurotransmission blockers, adhesive production/release inhibitors and enzyme/protein inhibitors, are put forward for natural antifouling products or shelf-stable chemicals. Several molecular targets show good potential for use as biomarkers in future mechanistic screening, such as acetylcholine esterase for neurotransmission, phenoloxidase/tyrosinase for the formation of adhesive plaques, N-acyl homoserine lactone for quorum sensing and intracellular Ca2+ levels as second messenger. The studies on overall responses to challenges by antifoulants can be categorized as general targets, including protein expression/metabolic activity regulators, oxidative stress inducers, neurotransmission blockers, surface modifiers, biofilm inhibitors, adhesive production/release inhibitors and toxic killing. Given the current situation and the knowledge gaps regarding the development of alternative antifoulants, a basic workflow is proposed that covers the indispensable steps, including preliminary mechanism- or bioassay-guided screening, evaluation of environmental risks, field antifouling performance, clarification of antifouling mechanisms and the establishment of sensitive biomarkers, which are combined to construct a positive feedback loop.
Antifouling Compounds from Marine Macroalgae
Authors: Dahms Hans , Dobretsov Sergey
Published: August 2017

Marine macroalgae produce a wide variety of biologically-active metabolites that have been developed into commercial products, such as antibiotics, immunosuppressive, anti-inflammatory, cytotoxic agents, and cosmetic products. Many marine algae remain clean over longer periods of time, suggesting their strong antifouling potential. Isolation of biogenic compounds and the determination of their structure could provide leads for the development of environmentally-friendly antifouling paints. Isolated substances with potent antifouling activity belong to fatty acids, lipopeptides, amides, alkaloids, lactones, steroids, terpenoids, and pyrroles. It is unclear as yet to what extent symbiotic microorganisms are involved in the synthesis of these compounds. Algal secondary metabolites have the potential to be produced commercially using genetic and metabolic engineering techniques. This review provides an overview of publications from 2010 to February 2017 about antifouling activity of green, brown, and red algae. Some researchers were focusing on antifouling compounds of brown macroalgae, while metabolites of green algae received less attention. Several studies tested antifouling activity against bacteria, microalgae and invertebrates, but in only a few studies was the quorum sensing inhibitory activity of marine macroalgae tested. Rarely, antifouling compounds from macroalgae were isolated and tested in an ecologically-relevant way.
Mini-Review: Antifouling Natural Products from Marine Microorganisms and Their Synthetic Analogs
Authors: Wang Kai-Ling , Wu Ze-Hong , Wang Yu , Wang Chang-Yun , Xu Ying
Published: August 2017

Biofouling causes huge economic loss and generates serious ecological issues worldwide. Marine coatings incorporated with antifouling (AF) compounds are the most common practices to prevent biofouling. With a ban of organotins and an increase in the restrictions regarding the use of other AF alternatives, exploring effective and environmentally friendly AF compounds has become an urgent demand for marine coating industries. Marine microorganisms, which have the largest biodiversity, represent a rich and important source of bioactive compounds and have many medical and industrial applications. This review summarizes 89 natural products from marine microorganisms and 13 of their synthetic analogs with AF EC50 values ≤ 25 μg/mL from 1995 (the first report about marine microorganism-derived AF compounds) to April 2017. Some compounds with the EC50 values < 5 μg/mL and LC50/EC50 ratios > 50 are highlighted as potential AF compounds, and the preliminary analysis of structure-relationship (SAR) of these compounds is also discussed briefly. In the last part, current challenges and future research perspectives are proposed based on opinions from many previous reviews. To provide clear guidance for the readers, the AF compounds from microorganisms and their synthetic analogs in this review are categorized into ten types, including fatty acids, lactones, terpenes, steroids, benzenoids, phenyl ethers, polyketides, alkaloids, nucleosides and peptides. In addition to the major AF compounds which targets macro-foulers, this review also includes compounds with antibiofilm activity since micro-foulers also contribute significantly to the biofouling communities.
Paulomycin G, a New Natural Product with Cytotoxic Activity against Tumor Cell Lines Produced by Deep-Sea Sediment Derived Micromonospora matsumotoense M-412 from the Avilés Canyon in the Cantabrian Sea
Authors: Sarmiento-Vizcaíno Aida , Braña Alfredo , Pérez-Victoria Ignacio , Martín Jesús , De Pedro Nuria , Cruz Mercedes , Díaz Caridad , Vicente Francisca , Acuña José , Reyes Fernando , García Luis , Blanco Gloria
Published: August 2017

The present article describes a structurally novel natural product of the paulomycin family, designated as paulomycin G (1), obtained from the marine strain Micromonospora matsumotoense M-412, isolated from Cantabrian Sea sediments collected at 2000 m depth during an oceanographic expedition to the submarine Avilés Canyon. Paulomycin G is structurally unique since—to our knowledge—it is the first member of the paulomycin family of antibiotics lacking the paulomycose moiety. It is also the smallest bioactive paulomycin reported. Its structure was determined using HRMS and 1D and 2D NMR spectroscopy. This novel natural product displays strong cytotoxic activities against different human tumour cell lines, such as pancreatic adenocarcinoma (MiaPaca_2), breast adenocarcinoma (MCF-7), and hepatocellular carcinoma (HepG2). The compound did not show any significant bioactivity when tested against a panel of bacterial and fungal pathogens.
Application of the Constitutive Model in Finite Element Simulation: Predicting the Flow Behavior for 5754 Aluminum Alloy during Hot Working
Authors: Huang Chang-Qing , Liu Lei-lei
Published: August 2017

The flow behavior of 5754 aluminum alloy was researched using the plane strain compression test for the range of 300–500 °C and 0.1–10 s−1. The experimental flow curves acquired directly from Gleeble-3500 show that deformation parameters have a significant effect on the flow curves. All curves show a broad peak due to the dynamic softening after the work hardening. In addition, the flow curves display a slight downward trend after reaching the peak stress at low and medium strain rates. This softening mechanism has been further investigated by the work hardening rate and the results show that the flow characteristics of 5754 aluminum alloy are mainly controlled by the mechanism of competition between hardening, dynamic recovery and continuous dynamic recrystallization. Based on the corrected true strain-stress curves, the constitutive model of the corresponding softening mechanism has been established by a linear regression method. Then, the developed model was embedded in the finite element (FE) analysis software (ABAQUS) by encoding the UHARD subroutine and the hot compression process of the alloy was simulated and analyzed. The simulation results show that the sample has an uneven flow in the deformation zone, which is consistent with the grain morphology of the corresponding region of the test sample. In addition, the simulated load-stroke values were well fitted to the experimental data. The predictive ability of the model was quantified by statistical indicators. It emerged that the FE of the embedded constitutive model effectively simulates the hot working process of 5754 aluminum alloy, which has reference value for actual processing.
Nonlinear Robust Adaptive Multi-Modal Vibration Control of Bi-Electrode Micro-Switch with Constraints on the Input
Authors: Mohammadi Mohsen , Eghtesad Mohammad , Mohammadi Hossein , Necsulescu Dan
Published: August 2017

Micro functionally graded material (FGM) structures are able to have proper functions in vast environments. In this paper, nonlinear governing equations of the size-dependent micro-switch are derived using modified couple stress theory. Effective external forces including fringing field of electrostatic force and Casimir force are considered. Two electrodes cooperate to track the in-plane motions of the micro continuous system by tuning the supply voltages of the electrostatic force. An adaptive projection law is proposed to compensate for the effect of error in the initial estimates of system parameters. To achieve more reliability, a robust active vibration strategy is presented to withstand external disturbances. At any time, just one electrode is operational, and optimization is performed to decrease the controller gains. The highly nonlinear inputs have a singularity in the dynamics of the system, which are known as pull-in instability, so for safety, the controller gains are chosen such that the pull-in voltage is avoided. The dynamic response of the system is simulated using a single mode or multiple modes to validate the effectiveness of the presented vibration control approaches. The effects of error of the initial estimate of system parameters, the effect of impulse and the influences of various volume fractions are studied.
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Authors: Vasconcelos Ariana , Pomin Vitor
Published: August 2017

Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in animals. Although GAGs are all composed of disaccharide repeating building blocks, the sulfation patterns and the composing alternating monosaccharides vary among classes. Interestingly, GAGs from marine organisms can present structures clearly distinct from terrestrial animals even considering the same class of GAG. The holothurian fucosylated chondroitin sulfate, the dermatan sulfates with distinct sulfation patterns extracted from ascidian species, the sulfated glucuronic acid-containing heparan sulfate isolated from the gastropode Nodipecten nodosum, and the hybrid heparin/heparan sulfate molecule obtained from the shrimp Litopenaeus vannamei are some typical examples. Besides being a rich source of structurally unique GAGs, the sea is also a wealthy environment of GAG-resembling sulfated glycans. Examples of these mimetics are the sulfated fucans and sulfated galactans found in brown, red and green algae, sea urchins and sea cucumbers. For adequate visualization, representations of all discussed molecules are given in both Haworth projections and 3D models.
Bioelectrochemical Changes during the Early Stages of Chalcopyrite Interaction with Acidithiobacillus Thiooxidans and Leptospirillum sp.
Authors: López-Cázares Irene , Patrón-Soberano O. , García-Meza J.
Published: August 2017

A bioelectrochemical study of charge transfer in the biofilm–chalcopyrite interface was performed to investigate the effect of surficial reduced sulfur species (RSS), in the form of non-stochiometric compounds or polysulfides (Sn2−) and elemental sulfur (S0) on a biofilm structure, during the earliest stages (1, 12 and 24 h) of chalcopyrite biooxidation by Acidithiobacillus thiooxidans alone and adding Leptospirillum sp. The surface of massive chalcopyrite electrodes was exposed to the bacteria, which were analyzed electrochemically, spectroscopically, and microscopically. At the studied earlier times, charge transfer and significant differences in the biofilm structure were detected, depending on the presence of Leptospirillum sp. acting on A. thiooxidans biofilms. Such differences were a consequence of a continuous chalcopyrite pitting and promoting changes in biofilm hydrophobicity. A. thiooxidans modifies the reactive properties of RSS and favors an acidic dissolution, which shifts into ferric dissolution when Leptospirillum sp. is present. A. thiooxidans allows H+ and Fe3+ diffusion, and Leptospirillum sp. enables to surpass the charge transfer (reactivity) barrier between the mineral interface and the ions. The observed changes of hydrophobicity on the interface are associated to ions and electrons activity and transfer. Finally, a model of S0 biooxidation by A. thiooxidans alone or with Leptospirillum sp. is proposed.
The Role of Water Glass in the Flotation Separation of Fine Fluorite from Fine Quartz
Authors: Zhang Guofan , Gao Yawen , Chen Wei , Liu Dezhi
Published: August 2017

Fluorite is the principal mineral of fluorine and usually coexists with quartz in deposits. The removal of fine quartz in fluorite concentrate is the main problem in fluorite flotation. In this study, the flotation tests on fluorite, quartz and a weight equivalent mixture (all less than 10 μm) using water glass (with different modulus) as depressants and sodium oleate as collector were conducted. The mechanism of fine quartz entering the fluorite concentrate was investigated through optional observations and rheology measurements on the flotation pulp. The particle interactions between fine fluorite and quartz under flotation-related conditions were analyzed through zeta potential measurements and DLVO calculations. The results revealed that there existed strong hetero-coagulation between fluorite and quartz particles in the flotation pulp, which could be the main reason for the quartz entering the fluorite concentrate in the flotation process. Water glass with higher modulus could eliminate the hetero-coagulation more totally but inevitably influences the flotability of fluorite.