bluuebunny/crossref_metadata_2025 huggingface dataset:
Contribution de la prospective des métiers à la coordination territoriale et aux pratiques managériales. Le cas du rapprochement de deux structures sanitaires et médico-sociales
Authors: Tissioui Mohamed , Joffre Clémence , Scouarnec Aline , Payre Sébastien
Published: July 2021

Cet article porte sur un instrument stratégique, la prospective des métiers, qui permet d’identifier l’impact des mutations sur le ou les métiers d’une organisation mais aussi sur les pratiques de management et les modalités d’organisation du travail. Nous en questionnons la portée et les limites en nous appuyant sur les résultats d’une recherche-intervention menée auprès de deux fondations opérant dans les secteurs sanitaire et médico-social en cours de rapprochement. Nous avons pu définir quatre scenarii permettant d’éclairer les décideurs afin de faire face aux mutations identifiées et de les articuler avec une stratégie managériale et des ressources humaines alternative que la nouvelle organisation pourrait mobiliser pour accompagner sa création et sa mise en place. Nos résultats contribuent aux travaux visant à développer des outils d’aide à la décision à l’intention des équipes managériales qui sont de plus en plus confrontées à la nécessité d’anticiper et de comprendre aussi bien les mutations externes de leur environnement sectoriel et d’affaires, que les mutations internes de nature managériale, humaine et organisationnelle.
Acute effect of two exercise intensity programs on interleukin-6, interleukin-1 beta and tumour necrosis factor-α in female futsalists
Authors: Zar A. , Ahmadi E. , Amani D. , Ramsbottom R.
Published: July 2021

Duration, intensity, and type of exercise can affect serum cytokine levels and change inflammatory indices. The present study aimed to examine the acute effect of two different exercise intensity programs on levels of circulating interleukin (IL)-6, IL-1β and tumour necrosis factor-α (TNF-α) in athletes. Eleven female futsal players aged 20.6±1.2 years completed this cross-over study. Participants performed, either a MI (moderate intensity: 60-65%) or a HI (high intensity: 75-80% heart rate reserve) exercise program. The study was performed on different days separated by a 1-week washout period. Each session consisted of 30 min running, either MI or HI. Blood samples were taken before (Pre) and immediately after (Post) each exercise session from an antecubital vein by venous puncture in a seated position. A Student’s t-test (P<0.05) was used to examine any difference between Pre and Post values. The results showed that IL-6 (P=0.22), IL-1β (P=0.90) and TNF-α (P=0.63) serum concentrations were not significantly different after moderate-intensity exercise. Similarly, high-intensity exercise did not significantly change serum concentrations of TNF-α (P=0.63), and IL-1β (P=0.18). However, HI caused a significant increase in IL-6 (P=0.04). A significant correlation was observed only between IL-1β and IL-6 (r=-0.761, P=0.01) after MI exercise. Based on the findings of the present study, the intensity of exercise can affect some cytokines, such as IL-6 in female futsal players.
Effects of rearing system and microbial inoculation on black soldier fly larvae growth and microbiota when reared on agri-food by-products
Authors: Gold M. , Fowles T. , Fernandez-Bayo J.D. , Miner L. Palma , Zurbrügg C. , Nansen C. , Bischel H.N. , Mathys A.
Published: July 2021

Black soldier fly larvae (BSFL) are widely used in recycling and upcycling of nutrients in agri-food by-products, but low and inconsistent BSFL rearing performance (i.e. larval growth, bioconversion rate, and substrate reduction) has been identified as a key challenge. The aims of this research were two-fold: (1) validate an existing closed rearing system design; and (2) assess whether a microbial inoculum derived from the rearing residue increases rearing performance. In controlled bench-scale experiments, BSFL were reared on tomato pomace (TP) and white wine pomace (WWP), along with food waste as control substrate. The two aims were assessed based on the following response variables: larval mass, substrate reduction, residue properties (i.e. pH, temperature, moisture content), and larval intestinal and residue microbiota. Higher BSFL mass (by 5.1 mg dry mass) at harvest on WWP and substrate reduction on TP (by 11.7% dry mass) in the closed system compared to the open system confirmed the potential of closed systems for rearing performance improvements of agri-food by-products. The rearing system also affected the residual moisture content and temperature, but only had a small effect on microbiota. Performance improvements by the closed rearing system design may be outweighed by insufficient aeration with pasty substrates and higher operational efforts for aeration and larval separation from the high-moisture residues. In contrast to the rearing system design, addition of the residue-derived microbial inoculum did not result in improved performance, nor did it alter intestinal and residue microbiota. Missing performance improvements could have been due to absent or low numbers of probiotic bacteria. The success of microbial substrate supplementation could be improved by studying effects of larval-associated microbes and developing cultivation methods that selectively amplify the beneficial (yet unknown) members of the microbial community. Our investigations aimed to increase the valorisation of low-value agri-food by-products in BSFL rearing.
Biomonitoring aflatoxin B1 exposure of residents from the Amazon region: a pilot study
Authors: Higashioka K.M. , Kluczkovski A.M. , Lima E.S. , Lucas A.C.S.
Published: July 2021

The present study was a pilot study that aimed to evaluate the occurrence of aflatoxins (AF) in the human diets and its presence in human urine as a metabolite (aflatoxin M1; AFM1). Volunteers from the Amazon region were evaluated before and after the consumption of 2 Brazil nuts/day for thirty days. At the end of 30 days (t=30) without the consumption of Brazil nuts, 9 samples (30%) were positive for AFM1. After 30 days (t=30) consuming 2 Brazil nuts per day, there was a reduction to 2 positive samples (7%). Questionnaires were also applied to volunteers, and the foods most often cited as consumed in their normal diet were cereals and bovine milk. However, there was no statistical relationship between these foods and the levels of AFM1 in the urine or in relation to those who already consumed Brazil nuts in culinary preparations or derived products. Despite the reduction of positive samples for AFM1 after 30 days of Brazil nut consumption, we suggest further studies regarding the clinical condition and genetics of individuals from the Amazon region, as well as the nutrient levels of the diet, e.g. for selenium, and which may protect the human body against aflatoxins.
Differences in Patient and Physician Perceptions of Urgency for Musculoskeletal Conditions During the COVID-19 Pandemic
Authors: Antonacci Christopher L. , Omari Ali M. , Zaifman Jay , Baig Ayesha F. , Sommi Corinne P. , Medvedev Gleb , Savoie Felix H. , Sethi Paul M. , Klein Gregg R. , Koerner John D. , Alberta Frank G.
Published: July 2021

In 2020, the coronavirus disease 2019 (COVID-19) pandemic limited musculoskeletal care to urgent or “nonelective” office visits and procedures. No guidelines exist to inform patients or physicians what meets these criteria. The purpose of this multi-institutional study was to describe the differences in perceptions of urgency for musculoskeletal complaints between patients and providers during the COVID-19 pandemic. An anonymous survey was distributed to patients who visited the authors' orthopedic clinics in January and February 2020 and practicing orthopedic surgeons. The surveys were administered in May 2020 after COVID-19 was officially labeled a pandemic and included questions regarding demographic information and perceptions of orthopedic urgency. A total of 1491 patients and 128 physicians completed the surveys. A significantly higher percentage of physicians considered the following diagnoses an appropriate indication for an urgent visit compared with patients: fracture (
P
<.001), acute dislocation (
P
<.001), infection (
P
<.001), neurologic compromise (
P
<.001), tumor (
P
<.001), acute tendon injury (
P
<.001), weakness (
P
<.001), inability to bear weight (
P
<.001), post-surgical problem (
P
<.001), and painful joint effusion (
P
<.001). There were no significant differences in the perception of urgency for the following conditions: bursitis/tendonitis (
P
=1.00), joint/extremity deformity without pain (
P
=.113), and loss of range of motion of a joint (
P
=.467). Younger patients and those with higher levels of education were significantly more likely to consider their conditions urgent. Patients may require additional education to prevent delay in treatment of urgent conditions—especially time-sensitive conditions such as neurologic compromise, tumors, and infections—when access to physicians is limited. [
Orthopedics
. 2021;44(4):e534–e538.]
Risk Factors for Mortality After Uncemented Bipolar Hemiarthroplasty for Geriatric Displaced Femoral Neck Fracture
Authors: Liu Kun , Sheng Jun , Zhang Huiyu , Liu Liu , Tang Yu , Zhu Zexing , Qiao Lin , Sun Ziqi , Yao Yuan
Published: July 2021

Uncemented bipolar hemiarthroplasty (UBHA) has been widely used to treat geriatric displaced femoral neck fracture (GDFNF), which results in a high 30-day mortality rate among the elderly. To date, few studies have focused on the risk factors for mortality after UBHA for GDFNF. In this retrospective study, elderly patients (age ≥70 years) who underwent UBHA for GDFNF were studied in order to provide helpful insight into the risk factors for mortality postoperatively. This retrospective study enrolled 835 elderly patients who underwent UBHA for GDFNF from January 2010 to December 2017. The Kaplan–Meier method and Cox regression analysis were used to identify significant risk factors predicting mortality after UBHA for GDFNF. Univariate analysis showed that underweight (body mass index <18.5 kg/m
2
), smoking, alcohol use, hypertension, chronic kidney disease, hypoproteinemia, low activities of daily living (ADL) score (0 to 2), and postoperative delirium were identified as the potential risk factors responsible for mortality after UBHA for GDFNF. Multivariate analysis suggested that underweight, hypoproteinemia, low ADL score, and postoperative delirium were significant risk factors predicting mortality after UBHA for GDFNF. Postoperative delirium was the most robust risk factor for mortality after UBHA for GDFNF. Underweight, hypoproteinemia, and low ADL score were also closely associated with mortality after UBHA for GDFNF. [
Orthopedics
. 2021;44(4):e570–e576.]
Bridge Plate Fixation of Distal Radius Fractures: Indications, Techniques, and Outcomes
Authors: Labrum Joseph T. , Ilyas Asif M.
Published: July 2021

Distal radius fractures are among the most commonly encountered injuries treated by orthopedic surgeons. The incidence of distal radius fractures appears to be on the rise. Although this injury is usually treated nonoperatively, surgical management is often indicated and involves several options, including percutaneous pinning, fragment-specific fixation, volar/dorsal/radial locked plating, intramedullary fixation, and external fixation. More recently, dorsal spanning bridge plating has been introduced for certain fracture patterns and patient circumstances. This article reviews the indications, surgical techniques, outcomes, and potential complications associated with bridge plating of distal radius fractures. The authors believe that this article will familiarize surgeons with an additional surgical technique that can be used to treat complex presentations of a common orthopedic injury. [
Orthopedics
. 2021;44(4):e620–e625.]
Use of 3D Navigation Versus Traditional Fluoroscopy for Posterior Pelvic Ring Fixation
Authors: Passias Braden J. , Grenier Greg , Buchan John , Buchan Daniel R. , Scheschuk Joseph , Taylor Benjamin C.
Published: July 2021

Unstable pelvic ring disruption is most commonly treated with closed reduction and percutaneous screw fixation. Traditional methods involve screw placement under fluoroscopic imaging, but with recent technologic advances, intraoperative 3D navigation can now be used to help with the insertion of sacroiliac screws. Various cadaver studies have shown that placement of sacroiliac screws under 3D navigation is more accurate than placement under traditional fluoroscopic guidance. This retrospective review of 134 patients evaluated the clinical use of 3D navigation vs traditional fluoroscopy for sacroiliac screw insertion at an urban level I trauma center. Analysis of surgical data showed a significantly longer imaging time with the conventional method compared with the more experimental 3D navigation (204.06 seconds vs 66.90 seconds,
P
<.01). Further, a significantly larger radiation dose to both the patient and the staff was seen with traditional fluoroscopy (80.1 mGy for each) compared with that of 3D navigation (39.0 mGy and 25.1 mGy, respectively). No statistically significant difference was seen for outcome or follow-up variables between the 2 extrapolated groups. These variables included length of hospital stay, infection, nerve injury, and hardware breakage. The authors advocate that 3D navigated sacroiliac screws are safe and effective for pelvic ring stabilization; this method may be especially applicable in certain difficult imaging situations, such as morbid obesity, bowel gas interference, and overlapping pelvic structures that make the sacral corridor difficult to discern with traditional 2D fluoroscopy. Safe placement of transiliac-transsacral screws (
P
<.01) occurred with 3D navigation, and there was a statistically significant increase in adequate screw placement in multiple sacral segments compared with single-level stabilization (
P
<.01). [
Orthopedics
. 2021;44(4):229–234.]
The Use of Telehealth for Orthopedic Consultations and Assessments: A Systematic Review
Authors: Ajrawat Prabjit , Young Shin Darren , Dryan David , Khan Moin , Ravi Bheeshma , Veillette Christian , Leroux Timothy
Published: July 2021

As a result of the coronavirus disease 2019 (COVID-19) pandemic, tele-health for orthopedic care is expanding rapidly. The authors sought to identify the evidence describing the effectiveness, barriers, and clinical applications of telehealth for orthopedic assessments and consultations. MEDLINE, PubMed, EMBASE, and the Cochrane Library were searched from inception to March 2020. Forty-seven studies were included, with the most common conditions evaluated being trauma related and the primary modality being videoconferencing. Available literature supports the use of telehealth for orthopedic consultations and assessments because it yields moderate-to-high patient and provider satisfaction, accurate examinations, cost-effectiveness, and reduced wait times. Most commonly reported concerns were professional liability, network security, and technical issues. Given the COVID-19 pandemic, rapid implementation and uptake of virtual assessment for patient care has occurred. The current evidence suggests that telehealth is capable of providing prompt access to quality, cost-efficient orthopedic consultations and assessments. [Orthopedics. 2021;44(4):198––206.]
Humic acid improved germination rate, seedling growth and antioxidant system of pea (Pisum sativum L. var. Alicia) grown in water polluted with CdCl2
Authors: Basahi Mohammed ,   Shaqra University, College of Science and Arts – Sajir, Saudi Arabia
Published: July 2021

Seeds of pea (Pisum sativum L. var. Alicia) were germinated for 5 d by soaking in distilled water or treated with cadmium and/or humic acid (HA). Interaction between humic acid and cadmium was previously discussed. However, the regulation of the humic acid / cadmium interaction during seed germination, the first crucial stage of the plant life cycle, need to be clarified. Seed germination is an important stage of the plant life, which is highly sensitive to surrounding medium changes, since the germinating seed is the first interface of material exchange between plant cycle and environment. Relationships among cadmium stress, HA-treatment, germination rate, and changes in reserve mobilization were studied. Cadmium disrupted the soaking process that was a major event of germination. Moreover, important solutes leakage due to Cd-treatment caused disorder in reserve mobilization from cotyledons to growing embryonic axes. The observed delay in germination rate and seedling growth after Cd-treatment could be explained, partially, by the disturbance in the mobilization of water and nutrients. NADH-and MDA-activities were considered as markers of oxidative stress. they were substantially increased after Cd-treatment compared with controls but decreased in presence of AH. Excessive NADH oxidase activities proved the install of oxidative stress in Cd poisoned seeds. We suggested an antagonist effect of Cd and HA on oxidative stress enzyme activities. Treatment of seeds with Cd and/or AH maintained a high level of guaiacol peroxidase activities during five days. The possible implication of GPOX against Cd toxicity and the improvement of the antioxidant system after AH treatment proved an important implication of these findings during germination.
Assessing the association between area deprivation index on COVID-19 prevalence: a contrast between rural and urban U.S. jurisdictions
Authors: Kitchen Christopher ,   Center for Population Health IT, Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, Hatef Elham , Chang Hsien Yen , Weiner Jonathan P , Kharrazi Hadi ,   Division of Health Sciences Informatics, Johns Hopkins School of Medicine, Baltimore, MD, USA
Published: July 2021

Background

The COVID-19 pandemic has impacted communities differentially, with poorer and minority populations being more adversely affected. Prior rural health research suggests such disparities may be exacerbated during the pandemic and in remote parts of the U.S.

Objectives

To understand the spread and impact of COVID-19 across the U.S., county level data for confirmed cases of COVID-19 were examined by Area Deprivation Index (ADI) and Metropolitan vs. Nonmetropolitan designations from the National Center for Health Statistics (NCHS). These designations were the basis for making comparisons between Urban and Rural jurisdictions.

Method

Kendall's Tau-B was used to compare effect sizes between jurisdictions on select ADI composites and well researched social determinants of health (SDH). Spearman coefficients and stratified Poisson modeling was used to explore the association between ADI and COVID-19 prevalence in the context of county designation.

Results

Results show that the relationship between area deprivation and COVID-19 prevalence was positive and higher for rural counties, when compared to urban ones. Family income, property value and educational attainment were among the ADI component measures most correlated with prevalence, but this too differed between county type.

Conclusions

Though most Americans live in Metropolitan Areas, rural communities were found to be associated with a stronger relationship between deprivation and COVID-19 prevalence. Models predicting COVID-19 prevalence by ADI and county type reinforced this observation and may inform health policy decisions.
Habelos, hainos. Detección remota de indicios arqueolóxicos mediante fotografía aérea e Lidar en castros de Galicia
Authors: Parcero-Oubiña César
Published: July 2021

Hay varios factores que explican que la llamada “arqueología aérea” haya tenido un desarrollo muy escaso en Galicia. Hoy en día, la creciente disponibilidad de conjuntos de datos de acceso público (ortofotografías, imágenes de satélite, Lidar) está cambiando este panorama. En este artículo repasamos esos factores y presentamos múltiples indicios de nuevos elementos arqueológicos que han sido identificados en el entorno de un amplio conjunto de castros en las provincias de A Coruña y Lugo. Entre los más de mil elementos identificados hay posibles estructuras enterradas en el entorno de esos castros (fosos, posibles caminos, restos de parcelas...), trazas de los sistemas defensivos e incluso un par de docenas de posibles nuevos castros. Todos estos hallazgos, que se produjeron de forma inicialmente casual y usando solo datos públicos de propósito general, justifican la potencialidad de desarrollar proyectos en esta dirección mediante el uso de plataformas, sensores y planificaciones de toma de imágenes específicamente diseñados con la finalidad de documentar elementos arqueológicos.
[gl] Varios factores explican que a chamada “arqueoloxía aérea” teña tido moi pouco desenvolvemento en Galicia. Porén, a crecente dispoñibilidade de fontes de información de acceso público (ortofotografías, imaxes de satélite, Lidar) está a mudar este panorama. Neste artigo repasamos eses factores e presentamos múltiples indicios de novos elementos arqueolóxicos que foron identificados na contorna dun amplo conxunto de castros nas provincias de A Coruña e Lugo. Entre os máis de mil elementos identificados hai posibles estruturas soterradas na contorna dos castros (foxos, posibles camiños, restos de parcelas...), trazas de partes dos sistemas defensivos hoxe desaparecidas e mesmo un par de ducias de posibles novos castros. Todos estes achados, que foron feitos de forma inicialmente casual e usando só datos públicos de propósito xeral, xustifican a potencialidade de desenvolver proxectos nesta dirección mediante o uso de plataformas, sensores e planificacións de toma de imaxes especificamente deseñados coa finalidade de documentar elementos arqueolóxicos.
Gaiferos de Mormaltán y el duque Guillermo X de Aquitania: entre Jofre de Monmouth y Manuel Murguía
Authors: Anguita Jaén José María
Published: July 2021

Desde su hallazgo por Manuel Murguía, el Don Gaiferos de Mormaltán es la pieza más popular del repertorio romancístico gallego, a pesar de que los especialistas en literatura de tradición oral lo hayan señalado como producto no genuino. En este trabajo se mostrará que, a pesar de que este juicio pueda estar bien fundamentado, es muy probable que un suceso como la peregrinación y muerte de Guillermo X de Aquitania en Compostela el año 1137 diera lugar a un material literario emparentado con el que da cuerpo al Don Gaiferos. Se pondrá además en relación al Gaiferos gallego con el Gaiferos de los romances viejos castellanos, de peripecia aparentemente tan disímil, a partir de la constatación de que ambos incorporan rasgos biográficos de los históricos duques de Aquitania de los siglos XI y XII. Se mostrará, finalmente, cómo el último duque aquitano, Guillermo X, pudo ser efectivamente conocido por el sobrenombre de Gaiferos, a partir de la alusión malévola que Jofre de Monmouth hace de él bajo la figura de Goffarius Pictus (Historia regum Britanniae 1, 18-20). Se concluye que a Murguía llegó, no sabemos por qué medios ni en qué estado, un material literario antiguo a partir del cual compuso su Gaiferos de Mormaltán. Este sería, por tanto, una versión facticia compuesta a partir de elementos tradicionales, y no una simple falsificación.
Dende o seu descubrimento por Manuel Murguía, o Don Gaiferos de Mormaltán é a peza máis popular do repertorio romancístico galego, a pesar de que os especialistas en literatura de tradición oral sinalárono como produto non xenuíno. Neste traballo mostrarase que, a pesar de que este xuízo poida estar ben fundamentado, é moi probable que un suceso como a peregrinación e morte de Guillerme X de Aquitania en Compostela o ano 1137 dese lugar a un material literario emparentado co que dá corpo ao Don Gaiferos. Poñerase ademais en relación o Gaiferos galego co Gaiferos dos romances vellos casteláns, de peripecia aparentemente tan disímil, a partir da constatación de que ambos incorporan trazos biográficos dos históricos duques de Aquitania dos séculos XI y XII. Mostrarase, finalmente, como o último duque aquitano, Guillerme X, puido ser efectivamente coñecido polo sobrenome de Gaiferos, a partir da alusión malévola que Xofre de Monmouth fai del baixo a figura de Goffarius Pictus (Historia regum Britanniae 1, 18-20). Conclúese que a Murguía chegou, non sabemos por que medios nin en que estado, un material literario antigo a partir do cal compuxo o seu Gaiferos de Mormaltán. Este sería, por tanto, unha versión facticia composta a partir de elementos tradicionais, e non unha simple falsificación.
A propósito de momo e corpo carnavalesco: de Joan Baveca e a sátira galego-portuguesa ao Cancioneiro Geral
Authors: Morán Cabanas Maria Isabel
Published: July 2021

En una cantiga de Joan Baveca a Pero d´Ambroa –ambos integrados en el “cancioneiro de jograis galegos”– se registra la única ocurrencia de momo en el corpus trovadoresco gallego-portugués. Hasta hoy, tal detalle no ha sido objeto de atención de los investigadores, que se limitaron prácticamente a reiterar la indicación de Rodrigues Lapa sobre su valor en un registro coloquial y en sentido figurado en su edición de Cantigas d’escarnho e de mal dizer (1965). Nuestro objetivo es formular una serie de reflexiones acerca de tal vocablo por varias vías: 1. análisis de hipóteses sobre su origen; 2. revisión de documentación coetánea a las cantigas y de textos literarios posteriores, concretamente los del Cancioneiro Geral que aluden a la representación de momos cortesanos; 3. cotejo de expresiones que vinculan risa y cuerpo bajo el prisma de la carnavalización. Así, ciertas isotopías literarias al servicio del humor, la historia de la (pre)teatralidad y la propuesta de una nueva entrada en el repertorio lexicográfico gallego-portugués son puntos nucleares de nuestro estudio.
[gl] Numa cantiga de Joan Baveca a Pero d´Ambroa –ambos integrados no “cancioneiro de jograis galegos”– regista-se a única ocorrência de momo no corpus trovadoresco galego-português. Até hoje, tal pormenor não tem sido objeto de atenção dos investigadores, que se limitaram praticamente a reiterar a indicação de Rodrigues Lapa sobre o seu valor num registo coloquial e em sentido figurado na edição de Cantigas d’escarnho e de mal dizer (1965). O nosso objetivo é refletir acerca de tal vocábulo através de várias vias: 1. análise de hipóteses sobre a sua origem; 2. revisão de documentação coetânea às cantigas e de textos literários posteriores, sobretudo os do Cancioneiro Geral que aludem aos momos cortesãos; 3. cotejo de expressões que ligam riso e corpo sob o prisma da carnavalização. Assim, certas isotopias literárias ao serviço do humor, a história da (pré)teatralidade e a proposta de uma nova entrada no repertório lexicográfico galego-português são os pontos nucleares do presente estudo.
El coto de Casasoá (Maceda, Ourense) en la Edad Media: estudio y colección documental
Authors: Pérez Rodríguez Francisco Javier
Published: July 2021

Se editan los tres pergaminos medievales que forman parte del archivo familiar correspondiente al pazo de Casasoá (Santiago de Zorelle, Maceda, Ourense). La publicación de esta documentación inédita se aprovecha para elaborar la historia medieval de un señorío de pequeñas dimensiones que, nacido en la edad media, logrará pervivir hasta la edad contemporánea.
[gl] Edítanse os tres pergameos medievais que forman parte do arquivo familiar correspondente ao pazo de Casasoá (Santiago de Zorelle, Maceda, Ourense). A publicación desta documentación inédita aprovéitase para elaborar a historia medieval dun señorío de pequenas dimensións que, nacido na Idade media, logrará sobrevivir ata a Idade Contemporánea.
Documentos de los Ulloa: el archivo de los Condes de Villalonso
Authors: Sánchez González Antonio
Published: July 2021

El objetivo de este artículo es presentar un fondo documental del Archivo Ducal de Medinaceli, la sección “Villalonso”, con varios centenares de documentos del señorío y condado leonés del mismo nombre, en tierras próximas a la ciudad de Toro, que ostentó una rama del linaje Ulloa, procedente de Galicia. El dominio fue erigido en condado en 1599 por el rey Felipe III. Más tarde, a partir del siglo XVII, los condes de Villalonso entroncaron con otras casas nobiliarias peninsulares, pasando su Archivo a incorporarse sucesivamente, primero en el siglo XVIII, al de los duques de Santisteban del Puerto y, definitivamente en 1818, al de los duques de Medinaceli. En este estudio, tras tratar primero la evolución histórica familiar de estos Ulloa, difundimos los contenidos del archivo condal de Villalonso, perfilamos su sistema de organización documental y trazamos la evolución secular del fondo documental.
[gl] O obxectivo deste artigo é presentar un fondo documental do Arquivo Ducal de Medinaceli, a sección “Villalonso”, con varios centenares de documentos do señorío e condado leonés do mesmo nome, en terras próximas á cidade de Toro, que ostentou unha rama da liñaxe Ulloa, procedente de Galicia. O dominio foi erixido en condado en 1599 polo rei Felipe III. Máis tarde, a partir do século XVII, os condes de Villalonso entroncaron con outras casas nobiliarias peninsulares, pasando o seu Arquivo para incorporarse sucesivamente, primeiro no século XVIII, ao dos duques de Santisteban del Puerto e, definitivamente en 1818, ao dos duques de Medinaceli. Neste estudo, tras tratar primeiro a evolución histórica familiar destes Ulloa, difundimos os contidos do arquivo condal de Villalonso, perfilamos o seu sistema de organización documental e trazamos a evolución secular do fondo documental.
Municipios rurais na Galicia do Antigo Réxime. O caso de Valladares: autogoberno, xurisdición e loitas señoriais
Authors: Pousa Diéguez Rodrigo
Published: July 2021

La Galicia del Antiguo Régimen aparece dividida en el siglo XVIII e dos tipos de entidades administrativas, que podemos calificar de locales: jurisdicciones y concejos. El análisis del fenómeno municipal rural de Galicia, pese a ser el mayoritario, sigue siendo una tarea pendiente. Por ello, este artículo se propone el estudio de un concejo rural, el de Valladares que, integrado en la jurisdicción de Muros, coexistía con el urbano de la capital jurisdiccional. Su estudio demuestra la capacidad de autogobierno de las comunidades rurales gallegas cuyos afanes no solo se dirigieron a la gestión de los recursos del común. Su importancia tuvo como resultado la enajenación de prerrogativas que, de no existir, tocarían a los oficiales de justicia; y en este caso jugó un papel esencial en la preservación de la unidad territorial bajomedieval, frente a la compartimentación sufrida por la jurisdicción en 3 señoríos distintos. Así mismo, el análisis de los cargos concejiles y sus funciones, además de los problemas que debieron afrontar, proporcionan una radiografia de la estratificación social de las comunidades rurales, los intereses comunes y sus estrategias.
[gl] A Galicia do Antigo Réxime aparece dividida no século XVIII en dous tipos de entidades administrativas que podemos calificar de locais: concellos e xurisdicións. Achegarse ao fenómeno municipal rural de Galicia, pese a ser o maioritario, segue a ser unha tarefa pendente. Se ben se ten afondado bastante no entramado administrativo de varias vilas e cidades as figuras políticas dos concellos rurais seguen a ser auténticas descoñecidas. Partindo disto proponse o estudo do concello de Valladares, integrado na xurisdición de Muros na que coexistía co concello da vila. O seu estudo amosa a capacidade de goberno das comunidades rurais galegas que dirixiu os seus afáns mais aló da xestión dos recursos comunais. A importancia destas unidades tivo como resultado a substracción de prerrogativas sobre o territorio que, de non existir, competerían en exclusiva aos oficiais señoriais de xustiza, e neste caso particular, a súa preservación e resistencia como unidade administrativa fronte á división do territorio baixomedieval do concello entre tres señoríos distintos —Corcubión, Muros e Outes—. A análise dos seus cargos, funcións e os problemas que deberon afrontar ofertan unha radiografía da estratificación social das comunidades rurais e os intereses dos grupos e as súas estratexias.
A pottery biography: considering the entire lifecycle of a pot in organic residue analysis
Authors: Drieu Léa
Published: July 2021

Over the past thirty years, the study of the exploitation of natural substances by ancient societies has been a major focus of organic residue analysis in ceramics. However, the mechanisms controlling the absorption and preservation of organic matter within the walls of pottery at all stages of a vessel’s lifecycle are still very poorly understood. Organic and mineral composition of the paste, surface treatments, porosity, environmental conditions of disposal of the vessel are likely to influence the organic signal preserved over time. Storage conditions of the archaeological material can also affect the preservation of organic matter after excavation. Recent studies are beginning to address these issues, and the first results are already refining the interpretations of organic residue analysis and opening up new fields of investigation, particularly with regard to the study of the ceramic manufacturing chaîne opératoire, burial environments and potential contamination.
Approche non invasive des peintures murales du prieuré Saint-Jean-l’Évangéliste de Trizay (Charente-Maritime, France)
Authors: Javel Jean-Baptiste , Beauvoit Emmie
Published: July 2021

Le prieuré Saint-Jean-l’Évangéliste de Trizay (Charente-Maritime) est un monastère saintongeais situé au bord de l’Arnoult. Prieuré appartenant à la Chaise-Dieu, dont les sources sont lacunaires, il fait l’objet d’une étude globale du bâti, de sa construction à son déclin au xviiie siècle. La présente étude porte sur les peintures murales qui sont conservées à différents endroits du monastère : dans le dortoir, le réfectoire et l’abside centrale de l’église. Les peintures du dortoir, les mieux conservées du corpus, sont attribuées au xviie siècle, d’après leur style et certains éléments figurés. Ces peintures sont également rapprochées, presque par défaut, de celles des voûtes du réfectoire représentant le tétramorphe. Cet article se focalise sur ces ensembles à travers une approche non destructive reposant sur plusieurs techniques d’imageries : photographie dans le visible, l’infrarouge et l’ultraviolet ainsi qu’imagerie hyperspectrale (400-1 000 nm). L’objectif est de pouvoir appréhender d’un point de vue technique les décors du prieuré de Trizay, à la fois dans leurs conceptions et leurs procédés de fabrication (matériaux et pigments employés). À travers ces nouvelles données, il devient possible de rediscuter la chronologie de ces ensembles picturaux, tout en les contextualisant dans le bâti et l’histoire du site.
Estimer le diamètre des bois carbonisés à partir de l’observation de la courbure des cernes de croissance des charbons de bois archéologiques : nouvelle contribution méthodologique
Authors: Paradis-Grenouillet Sandrine , Belingard Christelle
Published: July 2021

Les récents développements de l’anthracologie visent à renseigner les modes de collecte du bois, les pratiques sylvicoles et la physionomie évolutive des peuplements forestiers. Parmi ces développements, l’estimation du diamètre initial des bois carbonisés à partir de l’étude des charbons résiduels occupe une place centrale. Cette approche, initialement fondée sur l’observation de la courbure des cernes, s’appuie aujourd’hui sur la mesure précise du rayon de courbure (aussi appelé distance à la moelle) à l’aide de logiciels d’analyse d’images. Pourtant, force est de constater qu’encore trop peu d’études anthracologiques mobilisent cette approche, en particulier dans le milieu de l’archéologie préventive. Les raisons invoquées sont doubles : les équipements nécessaires (caméra et logiciels d’analyse d’images) ne sont pas encore assez démocratisés et la réalisation des mesures décuple le temps analytique. Cette approche devient donc incompatible avec les contraintes économiques de l’archéologie préventive. Pour dépasser cette limite, cet article propose une adaptation de la méthode qualitative basée sur l’observation de trois classes de courbures des cernes – courbe, intermédiaire, rectiligne – en définissant les valeurs limites des bornes de chacune de ces classes. Cette adaptation repose d’abord sur l’étude systématique des courbures de cernes dans des fenêtres d’observation posées sur une cible parfaite et six sections transversales de brins de taillis vieillis de chêne (Quercus robur L.) et de châtaignier (Castanea sativa Mill.). Cette première étape conduit à l’estimation des rayons de courbure maxima de chaque classe en millimètres. Dans un second temps, les valeurs limites obtenues sont testées sur un corpus anthracologique issu de trois charbonnières expérimentales pour lesquelles le diamètre initial des bois a été mesuré avant la carbonisation. In fine, les valeurs limites des trois classes de courbures sont validées et pourront être mobilisées dans les études anthracologiques ultérieures.
Transposition, scolarisation et culture scolaire : la question de la construction des savoirs scolaires
Authors: Denizot Nathalie
Published: July 2021

L’article se propose d’explorer à nouveaux frais la question de la construction des savoirs scolaires, initiée dès les années 1980-1990 dans le champ des didactiques disciplinaires par la théorie de la transposition didactique, en élaborant un appareil conceptuel cohérent autour de deux concepts : la scolarisation et la culture scolaire. Il le fera en mettant en perspective la didactique du français avec d’autres didactiques et d’autres disciplines (sociologie de l’éducation, histoire des disciplines…), et en revisitant l’histoire des didactiques (et particulièrement de la didactique du français) et de la construction du champ.
Science didactique et réputation littéraire : le sujet en question
Authors: Vuillet Yann , Védrines Bruno
Published: July 2021

Notre article, de nature théorique, s’intéresse au triple problème conceptuel du didactique, du littéraire et du sujet. Parce que les référents auxquels renvoient ces trois termes sont pluriels et discutables, nous approchons dans un premier temps la didactique, ses modèles, en tant qu’ils relèvent de l’espace sémantique d’une science sociohistorique. Nous abordons ensuite les implications, pour la didactique du français, de ce triple problème. Ceci nous conduit à argumenter en faveur du développement d’une théorie du « sujet didactique » pour traiter de l’enseignement et de l’apprentissage de « la » littérature. En décrivant des processus d’assujettissement induits par divers types de dispositifs, nous abordons finalement le problème du lien entre le psychisme individuel et les rapports sociaux, et proposons ainsi de réfléchir à la question de l’individualité et de ses formes historiques.
Cadrage, positionnement, niche, des notions pour en didactiser une autre : la « problématisation » dans l’écriture de recherche
Authors: Pollet Marie-Christine , Glorieux Carole
Published: July 2021

La problématisation et l’élaboration de la problématique sont souvent érigées en règles incontournables de l’écriture de recherche mais aussi en critères d’évaluation des productions étudiantes. Or, ces notions souffrent d’ambigüité sémantique, due notamment à la polysémie des mots issus du mot « problème ». Nous nous pencherons d’abord sur la question des représentations, définitions et caractérisations des notions en question. Nous tenterons ensuite d’éclairer la notion de problématisation, pour la rendre didactiquement opératoire. Nous la déclinerons au prisme d’autres notions telles que cadrage, niche et positionnement, en y associant des caractéristiques linguistiques selon nous observables, explicables et intériorisables pour les étudiants. Enfin, nous proposerons des pistes et analyses d’activités liées à cet objectif de didactisation et articulées à la découverte de la pratique de la recherche dans un champ disciplinaire.
Association of cycle threshold values of CBNAAT with severity and outcome in COVID-19
Authors: Garg Kranti , Sharma Karan , Gupta Aditi , Chopra Vishal
Published: July 2021

Determination of viral load through cycle threshold (Ct) values may act as a predictor of severity and outcomes in patients with corona virus disease 2019 (COVID-19). However, variable literature is available regarding this relationship. Our study attempted to explore this association and the effect of various socio-demographic and clinical parameters on severity and outcome of COVID-19.  Retrospective analysis of records of 731 patients whose nasopharyngeal/ oropharyngeal swabs were subjected to cartridge based nucleic acid amplification (CBNAAT) on Cepheid Xpert Xpress SARS-Cov-2 was done. Cycle threshold (Ct) values of N2 and E genes were studied in relation to severity and outcome of COVID-19. The viral load as determined by Ct values was classified as high (<25), medium (25.1-32) and low (>32). Association of socio-demographic and clinical parameters with respect to severity and outcome was also studied. Severity and mortality were significantly more in elder individuals, those belonging to the rural background, those with symptoms >7 days in duration before presentation and those with increasing number of co-morbidities (Severity: p<0.001, mortality: p <0.001, 0.005, 0.006 and <0.001 respectively). The Ct values of gene N2 and E inversely correlated with severity and mortality from the disease (N2 gene: p=0.001 for both severity and mortality, E gene: severity: p<0.001, mortality: p=0.016 respectively). The severity of the illness and chances of mortality were significantly lesser when the CT value of N2 gene was >32, in comparison when it was upto 25, and when between 25.1 and 32 (severity: p=0.032 and 0.003 respectively, mortality: p=0.018 and <0.001 respectively). Almost similar trends were seen with respect to E gene (severity: p<0.001 and 0.067 respectively, mortality p=0.175 and 0.005 respectively). Viral load as determined by Ct values of N2 and E genes can act as surrogate markers for prediction of severity and disease outcomes in COVID-19.
Comparison of analgesic efficacy of the conventional approach and mid-transverse process to pleura approach of the paravertebral block in video-assisted thoracoscopy surgeries
Authors: Swathi KB , Kamal Manoj , Kumar Mritunjay , Kumar Rakesh , Chhabra Swati , Bhatia Pradeep
Published: July 2021

Background and Aims:

The paravertebral block (PVB) is an effective alternative to thoracic epidural analgesia for post-operative analgesia in thoracic surgeries. Despite the use of ultrasound in PVB, the search for a safer approach continues. This study was conducted to compare the analgesic efficacy of conventional and mid-transverse process to the pleura (MTP) approach of the PVB.

Methods:

Forty patients aged between 18-60 years, posted for video-assisted thoracoscopic surgery, were enroled for this study. Patients were randomised into two groups using a random number table, and group allocation was done by the sealed opaque envelope method. One group received PVB by conventional approach (group CP). In contrast, patients in the other group (group MP) received PVB by the mid-transverse process to pleura (MTP) approach before induction of general anaesthesia under ultrasound guidance. The study's primary aim was to compare analgesic consumption in the first 24 hours. Secondary aims were comparing the Visual Analogue Scale (VAS) score, block performance time, dermatomal spread, haemodynamic parameters such as heart rate (HR), oxygen saturation (SpO2), and non-invasive blood pressure (NIBP), patient satisfaction scores, and complications observed. Data were analysed using Statistical Package for the Social Sciences version 23.

Results:

Demographic parameters, block performance time, and dermatomal distribution were comparable in both groups. We did not find any statistical difference in the analgesic consumption in the first 24 hours (P = 0.38), VAS at rest or on movement, complication rates, and patient satisfaction scores between the groups.

Conclusion:

The MTP approach of the PVB is as effective as the conventional thoracic paravertebral approach for post-operative analgesia in video-assisted thoracoscopic surgeries.
Amalgamation of quercetin with anastrozole and capecitabine: A novel combination to treat breast and colon cancers – An in vitro study
Authors: Rani Inala Mary Shobha , Pamidimukkala Kiranmayee
Published: July 2021

Context:

Globally, cancer stands as the principle cause of mortality and immediate attention on its treatment options is required. Natural compounds stay at first priority in encountering novel therapeutics without adverse effects.

Aim:

The aim of the study is to extract flavonol quercetin from leafy vegetables of Anethum graveolens L. and Raphanus sativus L. and find out its potential in combination with drugs used for chemotherapy to reduce the adverse effects of drugs.

Settings and Design:

Observational study.

Materials and Methods:

Column chromatography is used for quercetin extraction and anticancer activity of quercetin + anastrozole and quercetin + capecitabine were determined by (4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide assay (MTT), apoptosis assay, cell cycle analysis, mitochondrial membrane potential, and caspase 3 expression.

Statistical Analysis Used:

Cytotoxic assay results were assessed by mean, standard deviation and ANOVA; and results were compared for determining its significance.

Results:

The results noted that quercetin at very less concentration (16 and 31 μg/ml on Michigan Cancer Foundation-7 and 43 and 46 μg/ml on COLO 320) in combination with anastrozole and capecitabine was able to control the growth of cells, increase cell death, arrest cell cycle, and induce mitochondrial depolarization and expression of caspase 3.

Conclusions:

The natural compound used in the present study is effective in treating breast and colon cancer at minimal concentrations in combination with the drugs. This combinational treatment appears to be reported for the first time in the present study.
Emotion Regulation Effect of Baduanjin on College Students
Authors: Gu Qiang , Hu Qing-Chuan , Wei Yu-Long , Chen Kevin , Dong Jing-Jing , Li Shen-Yi , Wang Wei-Wei , Zheng Yi-Bin
Published: July 2021

Objective:

This study aimed to investigate the emotion regulation effect of Baduanjin Qigong on college students.

Methods:

The late positive potential (LPP) components were recorded while performing emotional pictures from 12 college students with Baduanjin Qigong experience and 12 with no experience of any mind–body exercises.

Results:

Under positive emotional stimuli, greater LPP amplitudes were observed in the experimental group in the frontal, central, and temporal areas than in the control group. Under negative emotional stimuli, greater LPP amplitudes were found in the experimental group in the prefrontal area and smaller amplitudes in the occipital area than in the control group.

Conclusion:

The results reveal the emotion regulation effect on the event-related potential of Baduanjin Qigong to college students. The findings suggest that the regulatory effect of Baduanjin Qigong on emotional stimulation may be a possible reason for reducing the symptoms of depression and anxiety.
Разрешимость нестационарных уравнений трехмерного движения теплопроводных вязких сжимаемых двухкомпонентных жидкостей
Authors: Mamontov Alexander Evgenievich , Prokudin Dmitriy Alekseevich
Published: July 2021

Рассматриваются уравнения, описывающие трехмерные нестационарные движения смесей теплопроводных вязких сжимаемых жидкостей в рамках многоскоростного подхода. Доказана теорема существования, в целом по времени и входным данным, обобщенного (диссипативного) решения начально-краевой задачи, соответствующей течениям в ограниченной области.
Библиография: 36 наименований.
Симметрии двумерной цепной дроби
Authors: German Oleg Nikolaevich , Tlyustangelov Ibragim Aslanovich
Published: July 2021

Данная работа посвящена описанию группы симметрий многомерных цепных дробей. В качестве многомерного обобщения цепных дробей мы рассматриваем полиэдры Клейна. Мы выделяем два типа симметрий: симметрии Дирихле, соответствующие умножению на единицы соответствующего расширения поля $\mathbb{Q}$, и так называемые палиндромические симметрии. Основным результатом работы является критерий наличия у двумерной цепной дроби палиндромических симметрий, аналогичный известному критерию симметричности периода цепной дроби квадратичной иррациональности.
Библиография: 15 наименований.