bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of papA, papC, and papG virulence genes revealed their association with antimicrobial resistance among uropathogenic Escherichia coli strains isolated from patients in Thi-Qar province, Iraq
Authors: Sura Mohammed Mahdi  , Halah Abdulkareem Yahya  , Murtadha kadhim Yasir  , Raheem Nayyef Naser  , Khashaa Abdul Khadhem Jaber
Published: February 2024

Infection of the urinary tract is one of the more common infections in the people of the world, which is more common in women due to the anatomical structure of the woman's body. The main cause of this infection is uropathogenic E. coli, followed by Klebsiella pneumoniae. This disease is controlled and treated by antibiotics, but one of the most important concerns in today's world is the spread of antibiotic resistance in different strains of bacteria. This resistance to antibiotics is caused by specific genes that increase the number of these identified genes every day. This study aims to find the frequency of three coding genes related to p fimbriae, namely papA, papC, and papG, from E. coli strains extracted from patients with urinary tract infections. Also, in this research, by conducting tests related to the detection of the antimicrobial resistance of the extracted strains and using statistical analysis, an attempt has been made to find a significant relationship between the presence or absence of a gene and resistance to antibacterials. At first, 110 urine samples were collected from patients with UTI in the Dhi Qar province of Iraq. In this research, bacterial culture methods in McConkey agar and advanced biochemical tests were used for primary confirmation of E. coli contamination, and Vitek2 and API E20 systems were used for secondary confirmation of bacterial contamination in suspected samples. Finally, the result of these tests was that all 110 samples were infected with E. coli. Then, samples resistant to the antibiotics Ampicillin, Tetracycline, Ciprofloxacin, Nitrofurantoin, and Cotrimoxazole, respectively, were detected by culturing in MuellerHinton agar medium and disc diffusion using the CLSI 2021 protocol. 36.36, 24.54, 29.09, 2.72, and 20% of the samples were resistant to these antibiotics, respectively. PCR was used to amplify gene fragments, and agarose gel electrophoresis was used to determine the presence of genes. The result was that the percentages of papG, papC, and papA genes were 61.81, 38.18, and 28.18, respectively. Finally, by performing a chisquare test in SPSS software, it was found that there is a significant relationship between the presence or absence of papA and papC genes with ampicillin and a significant relationship between papG and cotrimoxazole. These findings and the findings of other researchers can help us choose the right treatment and design new treatments by determining the antibiotic resistance factor
Morphological Appearance of Blood Vessels of Organs in Diabetes Mellitus
Authors: Sobirova Dildora Ravshanovna
Published: February 2024

This article explores the morphological alterations in blood vessels within various organs in individuals with diabetes mellitus. Diabetes mellitus, a chronic metabolic disorder, exerts a profound impact on vascular health, resulting in structural changes that contribute to a range of complications. Through a comprehensive review of existing literature and histological studies, this article delves into the diverse manifestations of vascular morphological changes in organs such as the heart, kidneys, eyes, and peripheral tissues. Understanding these alterations is crucial for elucidating the pathophysiological mechanisms underlying diabetic complications and developing targeted therapeutic strategies to mitigate their effects.
Studying the C174g Polymorphism of The Il6 Gene in the Formation of Diabetic Foot Syndrome in Patients with Diabetes Mellitus
Authors: Dadabaev Omonjon Talibzhanovich
Published: February 2024

The criteria for risk stratification of the formation of diabetic foot syndrome in patients with diabetes mellitus based on the carriage of the interleukin 6 gene were studied. The clinical group included 96 patients aged 40 to 75 years with diabetes mellitus complicated by diabetic foot syndrome. The control group consisted of 83 healthy individuals. The results obtained by the authors demonstrate that the presence of the C/G genotype of the C174G polymorphism of the IL6 gene has a clear correlation with predisposition to the development of diabetic foot syndrome. In order to effectively prevent the development of diabetic foot syndrome, it is advisable to recommend genotyping of the C174G polymorphism in the IL6 gene
Assessment of Surface Water and Estuarie Quality and Soil Condition Monitoring
Authors: Sharipova Gulnihol Idievna
Published: February 2024

Assessing the quality of surface waters and estuaries and monitoring soil health are critical to monitoring and maintaining the health of aquatic ecosystems and ensuring sustainable land management practices. This involves the assessment of various parameters, such as chemical composition, physical characteristics and biological indicators, to determine the overall condition and potential impact on human health and the environment
The influence of the degree of activity of rheumatoid arthritis on the parameters of stable metabolites of nitric oxide
Authors: Sibirkina M.V.
Published: February 2024

Rheumatoid arthritis (RA) is an immunoinflammatory disease characterized by progressive destruction of joints and damage to internal organs, which is based on disturbances in the humoral and cellular immune system [1,2]. In the absence of effective therapy, life expectancy in patients with RA is lower by 3 years in women and 7 years in men, primarily due to the high risk of developing comorbid diseases [5].
Pneumonia in Children with Vitamin D Deficiency
Authors: Khudaynazarova Nilufar
Published: February 2024

This article discusses the course of pneumonia in children with vitamin D deficiency. In the article, newborn children and their mothers are taken as examples
Preservation of fallopian tubes in ectopic pregnancy
Authors: Utamuratov Xurshid Qurbon o'g'li  , Mamatqobilova Sohiba Shokir qizi  , Mamatqobilova Sadoqat Shokir qizi
Published: February 2024

This study covers the application of laparoscopic partial tubal resection with end-to-end anastomosis can reduce the incidence of persistent ectopic pregnancy. In a normal pregnancy, the fertilised egg spends 4 to 5 days travelling down the fallopian tube before moving to the cavity of the uterus where it implants about 6 to 7 days after being fertilised. Most, but not all, ectopic pregnancies take place in the fallopian tube. Early detection of an ectopic pregnancy can prevent serious medical complications and may save the fallopian tube from permanent damage.
Monitoring Insulin and Glucose Levels in Hospital Najaf: A Critical Analysis of Diabetes Management
Authors: Ahmed Omar Kafi  , Suha Salah Khalaf  , Areej Amer Kafi  , Ahmed Samer Khalaf  , Hawraa Hammoud Hussein Jaber  , Nagham Ahmed Saleh
Published: February 2024

Diabetes mellitus, characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both, is a global health concern with increasing prevalence. In the city of Najaf, Iraq, Hospital Najaf plays a pivotal role in managing diabetes cases for a substantial population. Effective diabetes management is critical, as uncontrolled diabetes can lead to a range of complications. Monitoring insulin and glucose levels is pivotal in this context. This study employs a mixed-methods approach to comprehensively assess diabetes management at Hospital Najaf, encompassing both qualitative and quantitative data sources. Qualitative data was gathered through interviews with healthcare professionals and patients, while quantitative data included the analysis of medical records and surveys. Statistical analysis was performed using SPSS. Results reveal significant differences in sugar and insulin levels between healthcare professionals and patients with diabetes, underlining the importance of monitoring and intervention. Patient interviews highlight the need for education and culturally sensitive care. This study's insights aim to contribute to enhanced diabetes management and the well-being of individuals with diabetes in Najaf and beyond.
Viral Hepatitis Delta: An Underestimated Threat
Authors: Elmurodova A.A.
Published: February 2024

In the world, there are more than 350 million people infected with the hepatitis B virus, of which 15-25% (750 thousand) die each year due to the development of complications of liver cirrhosis and hepatocellular carcinoma. The proportion of patients with HBV who have a concomitant delta agent that dramatically complicates its natural course varies from less than 1% to more than 10% in different populations. Worldwide, 20 million people may be infected with hepatitis delta virus. According to expert estimates in the Republic of Uzbekistan, screening studies in risk groups in 2014 revealed the presence of HBsAg in 2.3% of the population. Among pregnant women and blood donors, the prevalence of HBV is 1.3% in 2021 and 1.2% in 2022, respectively. Given the fact that HDV RNA cannot replicate without contamination by HBsAg, the endemicity of HDV should directly depend on the prevalence of HBV in the country. However, according to current epidemiological studies, this relationship is not natural and the areas of circulation of the delta agent do not correspond to the prevalence of HBV.
Preoperative vaginal wash with povidone iodine solution to reduce post caesarean infectious morbidity
Authors: Zainab Jaber AI Budairi  , Hameed Faisal Al-Zaidy  , Mahdi Saleh Hadi
Published: February 2024

Post-operative infection is frequently seen in Caesarean section. Vaginal wash with 10% povidone iodine & Antibiotic prophylaxis may have significant impact in reduction of infections and thus the need to study their roles in sepsis prevention systematically.
Prospects And Disadvantages the Use of Collagen and Other Biotechnologies in The Treatment of Burn Wounds (Literature Review)
Authors: Gafurov Bekzod Tohirovich
Published: February 2024

In recent decades, new methods of treating burn wounds based on biotechnologies have emerged. The review presents the main materials for the treatment of burns that were created using tissue engineering-biological wound coatings and skin substitutes.
Mechanisms of Peroxide Oxidation in Patients with Chronic Brucellosis and Principles of Treatment
Authors: Farmanova M.A.
Published: February 2024

We observed 85 patients aged 17 to 74 years. All patients used standard general, serological, biochemical and statistical methods. According to clinical forms patients were distributed as follows: primary chronic brucellosis (PChB) - 22 (25.8%) and secondary chronic brucellosis (SChB) - 63 (74.2%). The subcompensation phase was observed in 62.3% of the examined patients, the decompensation phase was detected in 37.7%
Hepatitis-Induced Hemolysis in Pediatrics: A Rare Case Report
Authors: Dr. Amal Adnan Laylani
Published: February 2024

This article presents a case study of a 6-year-old boy diagnosed with acute Hepatitis A virus (HAV) infection compounded by glucose-6-phosphate dehydrogenase (G6PD) deficiency. The patient exhibited a constellation of symptoms, including low-grade fever, upper abdominal pain, fatigue, and anorexia, over an 8 to 10-day period. Notably, jaundice, dark-colored urine, and hepatomegaly were prominent clinical features. Laboratory investigations revealed severe intravascular hemolysis, evidenced by a decline in hemoglobin, elevated reticulocytes, and unconjugated hyperbilirubinemia. The diagnosis of HAV hepatitis was confirmed through positive IgM anti-hepatitis A virus. Over the subsequent two weeks, the patient experienced peak levels of serum bilirubin, AST, and ALT. Conservative management focused on avoiding hepatotoxic drugs, ensuring adequate urine output, and monitoring metabolic parameters. Gradual improvement was observed over the subsequent month, with a significant reduction in bilirubin levels, restoration of hemoglobin, and a decline in liver enzymes. The patient was discharged for outpatient follow-up, and four weeks post-onset, G6PD levels approached normal, emphasizing the importance of comprehensive care in such complex cases. This case underscores the intricate interplay between viral hepatitis and G6PD deficiency, contributing valuable insights into the clinical presentation and management of severe hemolysis in this specific population
The dangers of ionizing radiation that affect human safety and the environment :A review Article
Authors: Juomana Jabbar Saeed  , Maryam Jasim Hasan  , Hala Ahmed Rasheed  , Dr. ReyamNaji Ajmi  , Estabraq Mohammed Ati
Published: February 2024

The world is witnessing an increase in the spread of nuclear technology and the expansion of the use of radionuclide in industry, agriculture, medicine and other nuclear and radiological applications. This may be accompanied by an increase in accidents as the threat of potential risks from human exposure increases externally exposed to ionizing radiation and contamination of its internal organs with radionuclide. In order to protect people and workers from health harms associated with external exposure for ionizing radiation and indoor contamination with radionuclides, follow the principles of health prevention and control implementing rules and laws for the protection of ionizing radiation that ensure safety for humans and the environment reducing radiation risks.
Modern View on the Problem of Triple Negative Breast Cancer
Authors: Atakhanova N. E  , Almuradova D. M  , Ziyaev Sh. V
Published: February 2024

Environmental pollution, repeated artificial termination of pregnancy, and improper use of medications create conditions for the development of breast cancer (BC). According to the World Health Organization, “... throughout the world, breast cancer ranks first among malignant neoplasms in women and is characterized by high mortality. According to statistics, about 1.67 million new cases are diagnosed annually in the world, more than 571 thousand women die from breast cancer...” 1According to the literature, “...triple-negative breast cancer (TNBC) accounts for about 8-20% of all breast tumors, more often found in women before menopause, with early menarche, with the first pregnancy at an earlier age, with a short period of breastfeeding and increased body mass index ..." 2 . Frequent recurrence of the disease as a result of inadequate diagnosis and treatment, as well as the search for methods of its prevention are one of the pressing problems facing physicians.
Modern Views on The Diagnosis of Orthodontic Patients
Authors: Pulatov Khamidullo Talyat Ugli
Published: February 2024

Orthodontics is a specialized branch of dentistry that focuses on diagnosing and correcting irregularities in tooth and jaw alignment. Over the years, there have been significant advancements in the methods used to diagnose orthodontic patients. Modern orthodontic practices now rely on a variety of approaches to ensure accurate diagnoses. This article explores these modern views on the diagnosis of orthodontic patients
Sarcoptic Scabies Disease and Treatment Methods
Authors: Pulatov Boburbek Talyat Ugli
Published: February 2024

Scabies, caused by the Sarcoptes scabiei mite, is a highly contagious skin infestation that affects millions of people worldwide. It is characterized by intense itching, redness, and the presence of burrow tracks on the skin. Effective treatment methods are essential to alleviate symptoms and eradicate the mite infestation. This article discusses the disease and various treatment options available
The role of mineralocorticoid receptor antagonists in the prevention and treatment of chronic heart failure after acute myocardial infarction
Authors: Norbo‘toyev Olimjon Mustafaqul o‘g‘li
Published: February 2024

This review article examines the role of mineralocorticoid receptor antagonists (AMP) in the treatment of heart failure (CH) in patients who have suffered acute myocardial infarction (AMI). The pathogenetic basis of the effect of AMPs on myocardial remodeling after AMI is considered. The pharmacological characteristics of drugs of this class are described: spironolactone and eplerenone. The results of the main studies proving the protective role of eplerenone in patients who have suffered AMI with HF of varying severity (EPHESUS, EMPHASIS-HF, ALBATROSS, REMINDER) are covered. The effectiveness of eplerenone was analyzed depending on the timing of its administration. The safety of the drug in comparison with spironolactone was considered. In conclusion, it was concluded that it is advisable to use these drugs in routine therapy in acute, subacute and long-term periods of ST-segment elevation AMI and with a left ventricular ejection fraction ≤40%, heart failure or diabetes mellitus, when patients already receive angiotensin-converting enzyme inhibitors and beta blockers and in the absence of renal failure or hyperkalemia. In this case, preference should be given to eplerenone as a drug having the most convincing evidence base and having a favorable tolerance profile. The introduction into medical practice of effective, accessible generics of eplerenone allows expanding its use in real clinical practice
"Transformation of pancreatic secretion with intraduodenal administration of trypsin and amylase with nonspecific substrates for them."
Authors: Abduraxmanov Avazbek Xoshimovich
Published: February 2024

The results of the study on the effects of enter sorbents allowed us to draw a fundamental conclusion, in our view, that the inhibitory influence on the secretion of pancreatic enzymes is exerted by only the solubilized enzymes in the duodenum contents. Immobilized enzymes bound to enter sorbents lose or significantly reduce this ability to inhibit pancreatic secretion. The de-blocking effects are also induced by nutrients introduced intraduodenally. In our laboratory, it has been demonstrated (Korotko G.F., Baybekova G.D.) that starch as a substrate for amylase removes its selective inhibitory effect on the secretion of pancreatic amylase; the selective inhibition of pancreatic protein secretion is reduced by intraduodenal administration of protein, and emulsified fat eliminates inhibitory effects on pancreatic secretion of lipase. The fundamental similarity of effects between sorbents and nutrients, considering the latter as factors immobilizing enzymes, allows us to observe some external analogy between the comparable effects.
Demographic Indicators in The Republic of Uzbekistan and Their Importance in Medicine
Authors: Khasanova Shoirakhon Abdujabborovna
Published: February 2024

Demography is a science that deals with the laws of the renewal of the population. It studies the laws of birth, death, marriage and annulment of marriage, renewal of spouses and families, as a unit of these processes, the laws of the renewal of the population as a whole and their dependence on social causes. will try; it studies the age and gender composition of the population, marriage-related and family changes, and their interrelationship with demographic processes. It describes the number and density of the population, the ratio of the urban population to the rural population, religious beliefs, migration, as well as the dependence of these processes on economic and social indicators: income and employment level, education level, race and ethnicity.
Analysis Of Occupational Safety And Health Risk Using The Hazard And Operational Study (Hazops) Method For Repairman
Authors: Fenita Purnama Sari Indah  , Junaida Rahmi  , Ribka Milenia Elsaday Manurung  , Tri Okta Ratnaningtyas  , Syaiful Bahri
Published: February 2024

Knowledge of occupational safety and health is very important for every job, but in practice there are still violations of OHS committed by Repairman such as not using personal protective equipment which is a mandatory requirement to carry out when doing work. By not implementing the OHS program in the workshop, it will have a negative impact in the form of increased incidence of work accidents and occupational diseases. Hazard and Operability Study (HAZOPS) is an attempt to identify the hazards of a process if it deviates from what it should be, hazops is a very systematic, thorough, and complete technique. Based on the results of preliminary studies that have been carried out, it is found that Griya Motor 168 City Market South Tangerang has 6 workers, all workers do not use personal protective equipment, for this reason researchers are interested in examining risks using the HAZOPS method . The general purpose of this research is to analyze occupational safety and health risks using the Hazard and Operability Study (HAZOPS) method at the Griya Motor 168 Pondok Cabe Workshop in South Tangerang. This research is a qualitative research. The techniques used in data collection are field observations and interviews. Data analysis begins with identifying Occupational Safety and Health risks by determining study points (nodes), deviations, causes, consequences and actions. Based on the results of the study, 8 potential hazards were obtained with 2 high categories, 4 medium categories, and 2 low categories. With this research, it is hoped that the company will improve safety for workers to reduce the risk of work accidents, for PPE, it should be emphasized and controlled because there are still workers who are negligent in using PPE
Correlation Of Essential Micronutrient Metabolism In Adolescents With Neurocirculatory Dystonia Living In Conditions Of Iodine Deficiency
Authors: Sultanova Feruza Khoshimovna
Published: February 2024

Reproduction of offspring is a complex biological process in which not only the reproductive apparatus, but the entire organism as a whole is involved. Therefore, the causes leading to reproductive dysfunction must be sought not only in the reproductive system, but throughout the entire body.
D-dimer as Sensitive parameters in COVID-19 (Study of 200 patients)
Authors: Dr. Mohammed Kareem Ahmed  , Dr. Mohammed Adnan Khaleefah  , Dr. Mohamed Ismael Jawameer  , Dr. Duraid Khalil Ibrahim
Published: February 2024

The 2019 Chinese flu pandemic has been traced back to a novel virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The 2019 coronavirus illness has been designated as COVID-19. Methods two hundred covid-19 cases were validated by RT PCR in a multi-center, prospective, observational and interventional research. At admission, all patients had their oxygen levels, inflammation marker D-Dimer, and chest HRCT taken. primary emphasis and subsequent dialogue. Age, gender, comorbidities, BIPAP/NIV use, and outcome were recorded, as was the presence or absence of lung fibrosis. Medical professionals can rule out DVT and PTE in some individuals with the help of CT pulmonary angiography and lower limb venous doppler. For statistical purposes, the Chi-square test is applied
The relationships between Risk Factors and the changes of Histopathological of Tissue Colon Cancer in Iraq Patients
Authors: Sabreen S. Abd Alkreem Alsaqi
Published: February 2024

The transformation of an ordinary cell into a cancerous one could be a dynamic process which often involves the approval of oncogenes as well as deactivation of tumor suppressor properties (alterations). Most changes are emptied by cellular genome dauntlessness and repair components. In any case, many genetic changes give cells an advancement advantage and unused capacities, driving to their neoplastic alter. As other cancers, like melanoma, sarcoma, and lymphoma, could affect the colon, colon cancer, also known as colon carcinoma, affects the epithelium of colon. The uncontrolled proliferation regarding colorectal epithelial cells might be a hallmark of colorectal cancer (CRC). The multistep carcinogenesis hypothesis states that pigment cells go through a sequence of atomic alterations before they become totally dangerous cells. The inactivation related to the Adenomatous polyposis coli (APC) signaling pathway is the most frequent hereditary cause of activation. The pathology of damage includes oncogene changes, tumor suppressor qualities, and probably many signaling pathways, which put cancers at risk of metastasis. In advanced nations, CRC has a high disease-specific mortality rate and impacts over a million individuals annually. Worldwide, CRC ranks 3 rd in terms of the incidence in both women and men. Africa and Central and South Asia have experienced the biggest drops in CRC, whereas New Zealand, Australia, North America, and Europe have experienced highest change rates.
The Importance of Vitamin D And Calcium in Type 2 Diabetes
Authors: M.R. Umarova
Published: February 2024

The investigation into the involvement of vitamin D in the pathogenesis and prevention of type 2 diabetes has garnered widespread scholarly attention. Notably, vitamin D receptors are discernible in pancreatic beta cells and immune cells. In addition to its established function as the primary regulator of calcium absorption, vitamin D exerts influence on the activity of calcium-associated endopeptidases in beta cells, facilitating the conversion of proinsulin to insulin and augmenting insulin production. Within peripheral insulin target tissues, vitamin D governs insulin action through the modulation of calcium homeostasis. Further, vitamin D exhibits pronounced immunosuppressive properties. Noteworthy is the potential implication of vitamin D deficiency in the etiology of type 2 diabetes, manifesting in the inhibition of insulin secretion and enhancement of glucose tolerance. The article underscores the imperative for comprehensive research and clinical trials elucidating the multifaceted roles of vitamin D and calcium in maintaining a robust physiological framework. Insightful findings from studies conducted in Uzbekistan and globally underscore a prevailing inadequacy in the dietary intake of calcium and vitamin D among diverse populations, taking into account geographical, ethnic, and physiological variances. Emphasis is placed on the critical significance of sustaining optimal levels of calcium and vitamin D for skeletal health, particularly in the context of osteoporosis prevention and treatment.
Analysis of the Types of Epidemiology Diseases and Incidence Level in The Population
Authors: Xodjiyeva Gulirano Sayfullayevna  , Kamalov Shahzodbek Usman ugli
Published: February 2024

In this article, types of infectious diseases, allergies, nervous system, microorganisms, incidence rate
Gynecology of children and adolescents, sexual azo defects, or, disorders of the functioning of the menstrual cycle.
Authors: Yuldasheva Feruza Mardievna.
Published: February 2024

This article explores the often-overlooked domain of pediatric gynecology, focusing on sexual azo defects and disorders of the menstrual cycle in children and adolescents. Through an extensive literature analysis, the study investigates the prevalence, causes, and potential interventions for these conditions. The methods section details the approach taken, followed by the results, discussion, and concluding with practical suggestions for healthcare practitioners dealing with young patients in this field
Morphological And Morphometric Indicators of IntraPulmonary Blood Vessels in Childhood
Authors: Yoldosheva Malika  , Usmonaliyeva Zilola
Published: February 2024

In this article, researches were conducted on the morphological and morphometric indicators of intrapulmonary bronchus vascular wall tissues. The structures of the respiratory bronchioles of babies during the first childhood were studied. During the study, the following was proven: the layers of the respiratory bronchioles of young children between the ages of 4 and 7 are not well developed; the covering epithelium is multi-layered and single-layered, from the transformation of the connective tissue from the unformed. It was found that connective tissue-forming tissue, sparse chondroid and dense chondromatous tissue is covered with small cells
Early Lateral Closing Wedge Surgical Correction of Cubitus Varus Deformity Complicating Supracondylar Humeral Fracture in Children
Authors: Dr. Yousif Awad Jaber Almarawee
Published: February 2024

Cubitus varus deformity complicating supracondylar fracture of humerus in children usually implies a malunion from inappropriate treatment of the fracture . The resulting deformity can be solved only by osteotomy ,since the deformity once established it will not correct by remodeling . A lot of controversy is still present regarding the best age of the child to perform the corrective osteotomy . Cosmetic appearance is the most common indication for osteotomy
Analysis of the General Nervous System
Authors: Salomov Shoxabbos Nozimjon o’g’li
Published: February 2024

Thoughtful neurons have cell bodies situated in the intermediolateral sections, or horizontal horns, of the spinal string. The presynaptic strands leave the spinal rope through front roots and enter the foremost rami of T1-L2 spinal nerves and onto the thoughtful trunks by means of white rami communicants. From here, the strands might climb or drop the thoughtful trunk to a prevalent or substandard paravertebral ganglion, separately, pass to nearby front spinal nerve rami by means of dark rami communicants, or get through the storage compartment without synapsing and go on through an abdominopelvic splanchnic nerve to reach prevertebral ganglia. In view of the focal area of the thoughtful ganglia, presynaptic strands will generally be more limited than their postsynaptic partners
The Chemical Composition Of The White Carrak Plant And Its Medicinal Role
Authors: Salomov Shoxabbos Nozimjon o‘g‘l  , Khakberdiev Shukhrat Mahramovich
Published: February 2024

White carrack is a medicinal plant that has been used in medicine since ancient times. The composition of white carrack is rich in various vitamins and microelements. It is rich in vitamins A, E, F, K and V. Its leaves, roots, and seeds are used to make oil and whey. Due to its antioxidant properties, silymarin helps restore liver tissue
Creation Of Anti Stomatitis-S Gel in The Treatment Of Stomatits In Children
Authors: Raxmatova Dilnora Saidjonovna
Published: February 2024

The most urgent problem of dentistry is diseases of the oral mucosa, both in adults and in children of all age groups. The oral cavity is an environment with a high potential for the development of inflammatory processes, since the mucous membranes are attacked by microorganisms in the first place. Stomatitis is a disease of the oral mucosa that occurs with an inflammatory reaction, which is characterized by all the classic signs of inflammation. The study of treatment methods is an integral factor in the development of relapses and the formation of chronic stomatitis in children
PRAKTIKALITAS BUKU AJAR KALKULUS DERIVATIF UNTUK MENUMBUHKAN MOTIVASI BELAJAR MAHASISWA
Authors: Muhammad Taqwa
Published: February 2024

Pasca Pandemi Corona Virus Disease (Covid-19) mengharuskan melakukan pembelajaran mixed yaitu luring dan online termasuk mata kuliah kalkulus derivatif. Belajar online menuntut siswa memiliki motivasi yang kuat untuk belajar. Pengembangan Buku Ajar  merupakan salah satu strategi yang dapat menumbuhkan motivasi siswa. Tujuan penelitian ini adalah untuk mengembangkan Buku Ajar yang praktis dalam menumbuhkan motivasi belajar mahasiswa. Jenis penelitian ini adalah penelitian pengembangan, yaitu pengembangan Buku Ajar dengan model Plomp: (1) investigasi awal, (2) desain, (3) realisasi/konstruksi, (4) pengujian, evaluasi dan revisi, (5) implementasi. Subyek penelitian ini adalah mahasiswa Program Studi Pendidikan Matematika STKIP Andi Matappa. Instrumen penelitian adalah lembar kepraktisan buku ajar. Hasil penelitian skor kepraktisan buku ajar memiliki kriteria sangat praktis. Hal ini menunjukkan bahwa buku ajar kalkulus derivatif yang telah dikembangkan memenuhi unsur praktikalitas untuk menumbuhkan motivasi belajar mahasiswa.
Didactical Design for Application of Statistics Material for Class IV Elementary Schools
Authors: Tariska Nadia , Fuadiah Nyiayu Fahriza , Irawan David Budi
Published: February 2024

This research was motivated by learning obstacles experienced by students. These learning obstacles were obtained from the results of preliminary studies on statistics material. Thus, the aim of this research is to develop a didactical design for statistical material so that it can overcome the learning obstacles experienced by students. This research is qualitative research using the Didactical Design Research (DDR) method through three stages, namely a) Prospective Analysis, b) Metapedadidactic Analysis, and c) Retrospective Analysis. Data collection in this research is interviews, tests, documentation, photos. The results of this research show that there are several LOs experienced by students in statistics material, namely that there are still some students who cannot read data and there are still some who cannot make bar charts. HLT is structured based on the LO experienced by students, namely: 1) understanding the meaning of data, 2) understanding how to read data and interpreting data in the form of bar charts, 3) understanding how to present or make bar charts. The didactic design was implemented and obtained from the results of the final identification test, there was a decrease in LO compared to the initial diagnostic test. Based on these findings, a revision of the hypothetical didactic design was carried out and a revised didactic design was obtained.
The Influence of the Course Review Horay Learning Model Assisted by Video Media on Class IV Science Learning Outcomes
Authors: Alamiah Ayu , Marleni  , Riyanti Henni
Published: February 2024

This study aims to determine the effect of the Course Review Horay learning model supported by video media on science learning outcomes in class IV SD Negeri 43 Palembang. This study used an experimental method with a quasi-experimental design, namely nonequivalent control group design. The population in this research was 42 grade IV students and 42 research samples were taken using the non-probability sampling technique. Data collection used tests with data analysis using the Independent Sample t Test with the help of SPSS version 25. The results showed that there was an influence of the course review learning model. horay to the science learning outcomes of grade IV students at public elementary school 43 palembang. In the Independent Sample t Test, the value of Sig.(2-tailed) 0.020 <0.05 was obtained. Thus it can be concluded that there is a significant effect of the use of the course review horay model on science learning outcomes in class IV SD Negeri 43 Palembang.
SOCRATIC METHODS IN EDUCATION BASED ON CONFLICT DIALOGUE
Authors: Akhmedov B.A.
Published: February 2024

The structure and plot of the Socratic dialogue are analyzed. The main forms and principles of the method are revealed, and its results are correlated with the requirements of the Republican basic general education for the possible approbation of the method by teachers of humanities.
The Role of Museums for the Issue of Tourism Development
Authors: Tamar Zubitashvili
Published: February 2024

Tourism is an integral part of the life of our planet. This complex, highly profitable intersectoral complex is one of the main areas of the global economy, which contributes to a high level of employment, social welfare and quality of life, as well as economic unity and cultural diversity of states and regions of the world.

One of the ways of spiritual development of society is cultural tourism, in the development of which museums have an important place. It should be noted that significant investments have been made in the development and construction of museums. This seemingly conservative and quiet institution, like a large modern corporation, integrates with amazing speed into the processes of modern globalization, receives an unlimited number of visitors. It is aimed at attracting both local and foreign tourists.
Data services at the academic library: a natural history of horses and unicorns
Authors: Oliver Jeffrey , Rios Fernando , Carini Kiriann , Ly Chun
Published: February 2024

Objective: Increases in data-intensive research at colleges and universities is driving demand for data services provided by academic libraries. The current work investigates the distribution of library data services, how such services are offered, and the effect of resourcing on the amount of services offered by a library. Methods: We used a web-based inventory of 25 academic libraries at U.S. Research 1 (R1) Carnegie institutions to assess the state of data services at university libraries. We categorized and quantified services, and tested for an effect of library resourcing on the size of library data service portfolios.Results: Support for data management and geospatial services was relatively widespread, with increasing support in areas of data analyses and data visualization. There was significant variation among services in the modality in which they were offered (web, consult, instruction) and library resourcing had a significant effect on the number of data services a library offered.Conclusions: While a core subset of these data services are offered at most academic libraries, more specialized topics are restricted to well-resourced libraries. In light of the influence of resource scarcity on the number of services a library can offer, intra- and inter-campus partnerships will be critical to ensure campus support for data service needs.
Prerequisites for the Legal Prohibition of Propaganda of Non-Traditional Sexual Relations
Authors: Vodianaia Mariia , Miroshnichenko Anastasiya Vladislavovna
Published: February 2024

The object of the study is public relations regulating the issues of bringing to administrative responsibility for the promotion of non-traditional sexual relations and (or) preferences, sex change. The subject of the study is legislative and other normative legal acts regulating public relations in the field of administrative responsibility for the promotion of non-traditional sexual relations and (or) preferences, sex change. The purpose of the study is to identify the prerequisites of the ban imposed in the Russian Federation on the promotion of non-traditional sexual relations and (or) preferences, sex change, forecasting the development of the norm in question in a positive way. The study used universal dialectical, logical, descriptive, sociological, formal-legal research methods, etc. The relevance of the topic under consideration lies in the fact that in modern conditions of society's development, the preservation and protection of spiritual and moral values is one of the priorities. In connection with the active activities of a number of countries on the decomposition of public morality, Russian society and the state as a whole need to strengthen the protection of morality and public health. The novelty of the study lies in the fact that the analysis of scientific provisions in the direction of the study was carried out, as well as in the approach to the issue of administrative responsibility from the point of view of the need to improve legislation in the field of taking additional legal measures restricting the dissemination of information promoting homosexuality and other forms of sexual deviations. According to the results of the study, international and Russian legal acts concerning the issues of same-sex relations are analyzed, examples of popularization of such relations are considered and the results of a sociological survey are presented, confirming the tendency to increase the spread of facts of propaganda of non-traditional sexual relations. The scientific novelty also lies in the proposal to expand the scope of the concept of "propaganda of non-traditional sexual relations" by including propaganda of denial of traditional family values, asexuality, and sex change.
Legal Regulation of Personal Search, Seizure of Things and Documents as Measures of Administrative and Procedural Coercion
Authors: Tregubov Igor' Sergeevich
Published: February 2024

Personal search, seizure of things and documents are quite common measures of administrative and procedural influence, their purpose is to detect objects, substances, documents that are tools or means of committing an administrative offense. In other words, the appropriate measures of procedural influence are aimed at obtaining and securing evidence in the case of an administrative offense, and ultimately these measures contribute to improving the effectiveness of the execution of the decisions made in the case. In the course of the study, the author analyzed such a category as "personal inspection", assessed the legal regulation of this procedural event, drew attention to the need to improve the quality of both the organization of personal inspection, its procedural registration, as well as the need to respect the rights of the person in respect of whom personal inspection is carried out. The author shows the relationship of personal search with such procedural actions as the seizure of things and documents, as well as the relationship with delivery and administrative detention. The author cites various points of view regarding such a procedural action as "personal inspection", notes that personal inspection can also have a preventive function, this function of inspection is necessary in ensuring transport security, in countering the movement of things across the customs border. Personal search, as well as the seizure of things and documents, occupies an important place among the means of obtaining evidence in the proceedings on administrative offenses, and therefore, in order for the evidence to meet the requirement of admissibility, all necessary procedural requirements must be met during personal search. A personal search is a measure of procedural coercion, rather delicate, in this regard, actions that can humiliate a person are unacceptable during a personal search, the implementation of a personal search must be properly recorded.
An overview of ethnographic sources for the study of agriculture in medieval Novgorod
Authors: Volgina Nataliia Dmitrievna
Published: February 2024

The subject of this article is a set of ethnographic sources related to agricultural activities. This complex includes items from the expositions of ethnographic museums, photographs from the collections of local historians and the Internet, as well as the autobiography of the peasant I.S. Karpov. The use of ethnographic sources for the study of agricultural activities in the Middle Ages is extremely important due to the fact that archaeological material does not always reach our days in complete preservation. For example, such complex devices as ploughing implements in archaeological collections only have iron tips of their working parts, therefore, it is necessary to refer to ethnographic materials to restore their appearance. The same can be said about the technology of cultivating the land. To select the necessary material for this study, the works of Russian ethnographers and archaeologists devoted to the history of agriculture and folklore were studied. A selection of photographic materials from the collections of local historians and publicly available photographs from the Internet was also carried out. The article presents an overview of various types of ethnographic materials and the experience of their application for the reconstruction of agricultural activities of the inhabitants of medieval Novgorod according to archaeological data. The main contribution of the author to the research of the topic is the expansion of the range of ethnographic sources, which are most often involved in this kind of research. In this work, the experience of using not only physical material and photographs from the collections of ethnographic museums, but also folklore, was demonstrated for the reconstruction of agricultural processes that cannot be interpreted according to archaeological data. Traditional economic activities such as farming, hunting or various crafts are rooted in the deep past and retain their characteristics for a long time. This feature allows researchers to fully reconstruct certain processes about which only archaeological evidence has been preserved, which do not always reach our days in full.
Effects of Galvanic Skin Resistance Biofeedback on Perceived Stress in Individuals with High Blood Pressure: A Quasi-experimental Study
Authors: Tanna Krima , Khatri Subhash
Published: February 2024

Introduction: According to the World Health Organisation (WHO), hypertension is one of the leading causes of premature morbidity and mortality, both in industrialised and developing countries. Patients with arterial hypertension are advised to make lifestyle adjustments, such as increasing physical activity and reducing stress. Nowadays, a variety of relaxation techniques are used to reduce stress and tension. The practise of Biofeedback (BF) is regarded as a successful treatment for this purpose. Aim: To investigate the effect of Galvanic Skin Resistance Biofeedback (GSRBF) on perceived stress. Materials and Methods: In present quasi-experimental study, 53 individuals with high blood pressure, including prehypertensive and hypertensive individuals {Blood Pressure (BP)> 120/80 mmHg}, were included. Participants were recruited from various Medical and Physiotherapy Outpatient Departments (OPD) of private and Government hospitals and clinics in Veraval, Gujarat, India, from March 2022 to September 2022. Basic demographic data was collected, Blood Pressure (BP) was measured, and the Perceived Stress Scale (PSS) was administered. Participants were then connected to the GSRBF instrument and instructed to relax using a relaxation response technique. After 12 sessions, BP was measured again, and the PSS was administered. As the data were not normally distributed, a t-test was performed at a significance level of 95% (p<0.05). Results: The analysis revealed a significant decrease in PSS scores following GSRBF sessions, with a p-value of <0.05. Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) also showed a significant reduction, with a p-value of <0.05. Conclusion: The GSRBF demonstrated a significant reduction in perceived stress among individuals with high blood pressure, and it also showed a significant reduction in SBP and DBP. The present study provides valuable insights into the potential of GSRBF as an adjunct therapy for managing hypertension and promoting overall well-being.