bluuebunny/crossref_metadata_2025 huggingface dataset:
Epicardial Adipose Tissue in Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-analysis
Authors: Liu Bin , Li Yingrui , Du Jianlin , She Qiang , Deng Songbai
Published: October 2020

Objective: Epicardial adipose tissue (EAT) is a potential risk factor for obstructive sleep apnea (OSA). We performed a meta-analysis to assess the association of EAT with OSA.

Methods: The PubMed, EMBASE, Web of Science, Cochrane Library, and Wanfang databases were searched by two independent investigators for all observational studies assessing the association of EAT with OSA. Then we assessed the association of EAT thickness (EAT-t) and EAT volume (EAT-v) with OSA by a meta-analysis.

Results: Ten studies were included in the final analysis. Compared with that in controls, EAT-t in OSA patients was significantly increased (standardized mean difference 0.88, 95% confidence interval 0.72–1.05, P=0.000). Furthermore, EAT-t was greater in OSA patients than in controls with similar BMIs. However, we did not find significant differences in EAT-v between OSA patients and controls (standardized mean difference 2.46, 95% confidence interval −0.36 to 5.29, P=0.088). EAT-t in the mild, moderate, and severe OSA subgroups was greater than in the controls. In addition, there were significant differences in EAT-t among the mild, moderate, and severe OSA subgroups.

Conclusions: EAT-t was greater in patients with OSA than in controls, and EAT-t was also associated with the severity of OSA. These findings may provide a new clue for the pathogenesis and treatment of OSA.
Outcomes of Isolated Tricuspid Valve Surgery
Authors: Sánchez-Espín Gemma , Rodríguez-Capitán Jorge , Otero Forero Juan José , Becerra Muñoz Víctor Manuel , Rodríguez Caulo Emiliano Andrés , Such-Martínez Miguel , Porras-Martín Carlos , Villaescusa-Catalán José Manuel , Mataró-López María José , Guzón-Rementería Aranta , Melero-Tejedor José María , Gutiérrez-Carretero Encarnación , Jiménez Navarro Manuel Francisco
Published: October 2020

Background: Isolated tricuspid valve surgery is a rarely performed procedure and traditionally is associated with a bad prognosis, although its clinical outcomes still are little known. The aim of this study was to assess the short- and long-term clinical outcomes obtained at our center after isolated tricuspid valve surgery as treatment for severe tricuspid regurgitation.
Methods: This retrospective study included 71 consecutive patients with severe tricuspid regurgitation who underwent isolated tricuspid valve surgery between December 1996 and December 2017. Perioperative and long-term mortality, tricuspid valve reoperation, and functional class were analyzed after follow up.
Results: Regarding surgery, 7% of patients received a De Vega annuloplasty, 14.1% an annuloplasty ring, 11.3% a mechanical prosthesis, and 67.6% a biological prosthesis. Perioperative mortality was 12.7% and no variable was shown to be predictive of this event. After a median follow up of 45.5 months, long-term mortality was 36.6%, and the multivariate analysis identified atrial fibrillation as the only predictor (Hazard Ratio 3.014, 95% confidence interval 1.06-8.566; P = 0.038). At the end of follow up, 63.6% of survivors had functional class I.
Conclusions: Isolated tricuspid valve surgery was infrequent in our center. Perioperative mortality was high, as was long-term mortality. However, a high percentage of survivors were barely symptomatic after follow up.
Surgical Options for Transposition of the Great Arteries With Ventricular Septal Defect and Left Ventricular Outflow Tract Obstruction: Evolution and Functional Impact
Authors: Salem Alsayed
Published: October 2020

Surgery for D-transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction has continuously evolved to achieve optimal hemodynamic performance across the right and left ventricular outflow tracts, include predominantly native tissues, and preserve pulmonary valve function. Classically, three types of repair are applied: Rastelli, REV, and translocation procedures. The concept of translocation remains more radical and exposed to many modifications. Its extensive reconstructive nature extends its application to similar lesions with discordant ventriculo-arterial connection. We tried to compare the values and limitations of these surgical options, emphasizing how a more anatomical repair could impact the functional outcome.
Programmed Cell Death 2-Like (Pdcd2l) Is Required for Mouse Embryonic Development
Authors: Houston Brendan J , Oud Manon S , Aguirre Daniel M , Merriner D Jo , O’Connor Anne E , Okutman Ozlem , Viville Stéphane , Burke Richard , Veltman Joris A , O’Bryan Moira K
Published: October 2020

Globozoospermia is a rare form of male infertility where men produce round-headed sperm that are incapable of fertilizing an oocyte naturally. In a previous study where we undertook a whole exome screen to define novel genetic causes of globozoospermia, we identified homozygous mutations in the gene PDCD2L. Two brothers carried a p.(Leu225Val) variant predicted to introduce a novel splice donor site, thus presenting PDCD2L as a potential regulator of male fertility. In this study, we generated a Pdcd2l knockout mouse to test its role in male fertility. Contrary to the phenotype predicted from its testis-enriched expression pattern, Pdcd2l null mice died during embryogenesis. Specifically, we identified that Pdcd2l is essential for post-implantation embryonic development. Pdcd2l−/− embryos were resorbed at embryonic days 12.5-17.5 and no knockout pups were born, while adult heterozygous Pdcd2l males had comparable fertility to wildtype males. To specifically investigate the role of PDCD2L in germ cells, we employed Drosophila melanogaster as a model system. Consistent with the mouse data, global knockdown of trus, the fly ortholog of PDCD2L, resulted in lethality in flies at the third instar larval stage. However, germ cell-specific knockdown with two germ cell drivers did not affect male fertility. Collectively, these data suggest that PDCD2L is not essential for male fertility. By contrast, our results demonstrate an evolutionarily conserved role of PDCD2L in development.
La imprenta en México: cuestiones terminológicas y tipología de los primeros impresos americanos
Authors: Lorente Queralt Núria
Published: October 2020

La cultura impresa mexicana tiene su origen en los albores del siglo XVI con la instalación de la primera prensa tipográfica en el continente y la fabricación de las primeras ediciones impresas en el continente. Esta primitiva producción, y cada uno de los ejemplares que la integraba, fechados entre 1539 y 1634, recibieron el nombre de incunables americanos a semejanza de los primeros libros impresos en Europa entre la creación de la imprenta y el 1 de enero de 1501. Sin embargo, poco tenían que ver los iniciales americanos con los primeros textos impresos en Europa hacía más de cincuenta años, por lo que la utilización del término incunable resultó desde un primer momento confusa. Este artículo problematiza la cuestión terminológica a partir de una breve aproximación a la tipología de los primeros textos impresos en América, así como a las sucesivas mutaciones que experimentó la imprenta desde su creación hasta su llegada al Nuevo Mundo.
La cara oculta de la realidad: elementos fantásticos en La princesa y el granuja de Benito Pérez Galdós
Authors: Sánchez Martínez Andrés
Published: October 2020

Este artículo analiza el funcionamiento de los elementos fantásticos en «La princesa y el granuja» de Benito Pérez Galdós. Para ello, se parte de una revisión del concepto de lo fantástico en el relato breve galdosiano, lo que permite así cuestionar el tradicional menosprecio de la crítica a esta parte de la producción del canario. Desde una concepción amplia de realismo, Galdós ensayará en el cuento estrategias narrativas y temáticas de la literatura fantástica decimonónica. En la práctica, ello se cifrará en la construcción de diversas esferas semióticas que, dudando de la mímesis, anticipan el cuestionamiento de la realidad social de sus novelas. Palabras clave: Benito Pérez Galdós, literatura fantástica, realismo literario, cuento fantástico.
Degradations of tannin and saponin and changes in nutrition during co-composting of shell and seed cake of Camellia oleifera Abel
Authors: Zhang Jinping , Ying Yue , Yao Xiaohua , Huang Weihua , Tao Xiangsheng
Published: October 2020

The degradation processes of tannin and saponin were studied during co-composting of the shell and seed cake of Camellia oleifera Abel. Four treatments were designed, with the dry weight of the seed cake accounting for 30% (A1), 25% (A2), 20% (A3), and 10% (A4) of the shell weight. During the composting, the duration and the highest temperature of the thermophilic phase were positively correlated with the addition proportion of seed cake. The degradation rates of tannin and saponin were positively correlated with the addition proportion of seed cake, but the C/N ratio and final tannin content were negatively correlated with it. The saponin content ultimately contributed to approximately 2% of the final compost mass. The final content of saponin and tannin decreased by 68.9 to75.2% and 34.6 to 59.5%. The organic matter and total nutrient content (N, P2O5, and K2O) increased with the increasing proportion of seed cake. An addition proportion of 30% of Camellia oleifera seed cake is recommended to produce homogenous compost. Overall, the addition of the seed cake promoted the maturity, fertilizer quality, and safety of the co-compost product.
Chemical and thermal characterizations of Pinus sylvestris and Pinus pinaster
Authors: Mertoglu Elmas Gulnur , Yilgor Nural
Published: October 2020

Chemical and thermal aspects of Pinus sylvestris and Pinus pinaster were characterized, with consideration of non-extracted and cylohexane-ethanol (EtOH)-extracted woods, holocellulose, and α-cellulose. The chemical properties including cylohexane-EtOH solubility of wood were determined by standard test methods, holocellulose, α-cellulose, lignin, and ash components. Fourier transform infrared–attenuated total reflection spectroscopic (FTIR-ATR) analysis revealed changes in the chemical structure of the specimens. Lignin peaks were still observed in holocelluloses’ spectra, and substantial loss of polysaccharides were also detected. Moreover, the α-cellulose spectra of both softwoods included bands belonging to polyoses. Pinus pinaster‘s holocellulose, α-cellulose, and ash contents were higher than those of Pinus sylvestris but lignin and cylohexane-EtOH-solubility amounts were lower. The mass loss during degradation stage of Pinus sylvestris and Pinus pinaster was observed in the extracted wood respectively as 73.0 and 74.5% within the 188.7 to 422.9 °C range. The highest mass loss for Pinus sylvestris and Pinus pinaster in the carbonization step was formed in their holocelluloses respectively as 22.9 and 22.5% from 426 °C to 1017 °C.
A predictive model for the cutting force in wood machining developed using mechanical properties
Authors: Naylor Andrew , Hackney Phil , Perera Noel , Clahr Emil
Published: October 2020

In this study a number of work-piece variations were evaluated whilst limiting the cutting conditions. Eight wood species controlled at four moisture levels were machined along and across the wood grain. The tool used during cutting was designed to resemble a rip saw tooth with zero rake angle and narrow edge width. Each work-piece variation machined in the cutting tests was subjected to mechanical tests that evaluated bending properties across the grain and shear properties along the grain. The regression model establishes a relationship between the bending properties for cutting forces across the grain, as well as shear properties for cutting forces along the grain. F and R² values show that the elastic properties of the wood in bending and shear have less influence on the cutting forces when compared to the strength and toughness. Additionally, density is seen to have less influence on the cutting force along the grain. This is explained by the tool passing through an unquantifiable proportion of early and latewood fibers from the annual growth rings. Cutting across the grain, the tool is forced to machine through approximately the same proportion of earlywood and latewood fibres.
Conﬂictos discursivos: un estudio de Adiós, Ayacucho desde la perspectiva del análisis crítico del discurso
Authors: Mere Collazos Milagros
Published: October 2020

Analiza la novela Adiós, Ayacucho de Julio Ortega desde el análisis crítico del discurso (ACD) que permite observar los recursos utilizados por el narrador para evidenciar las diferencias sociales y demandas de los desfavorecidos representados en la novela, los que expresan un discurso claramente distinguible. Parte de la premisa: en las obras literarias, el discurso empleado por el narrador, brinda información sobre la historia relatada y visualiza la relación establecida entre los diferentes actores de una sociedad en un momento determinado. En efecto, los diversos modos de interacción entre los grupos sociales a través del tiempo han ocasionado que algunos adquieran más poder que otros, lo que se evidencia en y a través del uso del lenguaje.
Caitro Soto: “De canto, baile y cadenas”. Testimonio y cultura Afroperuana
Authors: Carazas Milagros
Published: October 2020

Analiza la obra De cajón Caitro Soto. El duende de la música afroperuana (1995), un libro dedicado al artista Carlos Soto de la Colina (1934-2004). Indaga su historia de vida, la tradición oral, los géneros musicales afroperuanos. Reﬂexiona sobre la canción afroperuana y su contenido.
Ideología política en la correspondencia de Julio Ramón Ribeyro con su hermano Juan Antonio (1953-1983)
Authors: Coaguila Jorge
Published: October 2020

El contenido político es uno de los aspectos fundamentales en la correspondencia de Julio Ramón Ribeyro con su hermano Juan Antonio, remitida de 1953 a 1983. El escritor limeño esboza en ella los rasgos más generales de su ideología política, cuestión no abordada ni estudiada hasta hoy. Estas cartas nos permiten conocer de manera extensa las reﬂexiones de Ribeyro acerca de la realidad social del Perú y del mundo en una época bastante convulsa y compleja: la segunda mitad del siglo XX. Son reﬂexiones casi inexistentes en el resto de su obra fccional, literaria o intelectual en general. Así, esta correspondencia posee un alto valor histórico, teórico y literario expresados en un pensamiento ideológico político.
El arte de escribir, el yo poético y las instancias creativas
Authors: Gonzáles Márquez Carla Vanessa
Published: October 2020

El trabajo busca determinar la naturaleza de la escritura creativa y qué procesos se cumplen desde el momento en que el escritor ejecuta la labor de construir los universos de fcción que constituyen una obra literaria, ya sea un cuento, una novela o un poema. Asimismo, busca defnir la existencia de un yo poético como sujeto discursivo en el universo de la fcción lírica.
Los felices años veinte de Felipe Fox-trot, traducción y creación en la obra de Felipe Pinglo Alva
Authors: Sarmiento Herencia Rodrigo
Published: October 2020

El siguiente artículo trata sobre el impacto que tuvo la música popular estadounidense, particularmente el fox-trot, en la producción de uno de los más importantes personajes de la canción criolla de Lima, Felipe Pinglo Alva. Pese a las fronteras lingüísticas, delimitadas por el desconocimiento del idioma en que llegaban los éxitos cantados que todos querían bailar, el ritmo de moda le propició al compositor barrioaltino un espacio único dentro de su espectro creativo donde pudo verter lo más fresco de su genio literario para así apropiarse y nacionalizar estos nuevos aires que la potencia norteamericana difundió por toda América Latina.
Poética del cuento moderno de Flores nocturnas de Miguel Bances
Authors: Bances Gandarillas Miguel Luis
Published: October 2020

El presente artículo trata de establecer la poética del libro de cuentos Flores nocturnas de Miguel Bances. Se parte de la idea de que el ejercicio intelectual que supone la reflexión de la obra por parte del propio autor debe alejarse de ideas generales y se debe, más bien, complejizar las nociones de relato, personaje y lenguaje. En primer lugar, se propone la reflexión sobre dos paradigmas del cuento moderno (Poe y Chéjov) con el propósito de establecer vínculos con el género del relato. En segundo lugar, se busca la adscripción de los relatos de Flores nocturnas con el cuento epifánico. En tercer lugar, se plantea que el personaje debe ser estudiado en la dimensión crítica que propone la relación sujeto-modernidad. Finalmente, se discute la visión de la realidad a partir de la noción de lenguaje con que opera Flores nocturnas.
Eros y Tanatos: representación de la melancolía en Ophelia
Authors: Rodríguez Vásquez Erika
Published: October 2020

El objetivo principal de este artículo es discutir la representación de la melancolía como resultado de la tensión entre lo erótico y lo mórbido en el poemario Ophelia. Este predominante sentimiento melancólico en los versos, que constituyen el libro se analizará a partir de la correspondencia entre dos ejes: el eros y el tanatos, como fundamentos en la percepción de un tono catastrófico y el carácter mítico del personaje ofeliano. En ese sentido, se pondrá énfasis en evidenciar la presencia de un discurso y tono en el marco de creación de fin desiglo.
Estudios críticos sobre la violencia social, el compromiso político-ciudadano y la veracidad histórica en Noticia de un secuestro (1996)
Authors: Delgado Del Aguila Jesús Miguel
Published: October 2020

Noticia de un secuestro (1996), novela periodística del Premio Nobel de Literatura Gabriel García Márquez, ha permitido que se realicen trabajos hermenéuticos en función de los Estudios Culturales, ya que su contenido abarca períodos históricos de Colombia, la Sociología, la Criminología y la política: todo ello vinculado con la prosa literaria del escritor. En esta oportunidad, lo que represento son tres vertientes de investigación que se han desarrollado sobre la base del estudio de esta obra, las cuales son la manifestación intencionada de la violencia social en Colombia, la constitución del compromiso político-ciudadano y la fidelidad autoral por la exposición histórica en la misma novela. La finalidad de la confrontación y el diálogo intertextual con la crítica literaria es la de establecer un panorama hermenéutico con respecto a lo determinado en Noticia de un secuestro (1996).
La transformación en seres adversos: el caso de la jupaymula
Authors: Huamán Antonio Timna Yulisa
Published: October 2020

Una diversidad de seres míticos y mágicos confguran el imaginario andino, un grupo de ellos son califcados como negativos por la acción hostil que manifestan en su relación con los pobladores. En este trabajo se exponen los rasgos generales de estos seres como resultado de la transformación morfológica que afecta a su naturaleza original, la cual implica cambios en su conducta habitual y en la función que desempeñan como parte de pacha. Asimismo, se enfatiza en la fgura de la jupaymula —sincretiza las concepciones mítico-religiosas andinas e hispanas— determinando sus características, su proceder antes, durante y después de la metamorfosis, de donde se concluye que su conversión es una sanción por infringir los principios morales de su comunidad, vinculados con el incesto. Se corrobora que los seres adversos, en la mayoría de los casos, se constituían instrumentos para el control social.
Ficcionalidad y subalternidad en el mundo representado de Sarita Colonia viene volando
Authors: Lozano Mejía Jamess
Published: October 2020

Proponemos una lectura que considere a Sarita Colonia viene volando (1990) una historia que tiene su origen o pretexto en la cultura no ofcial (subalterna), representada por su protagonista y sus feles. La representación de la subalternidad en la novela establece la presencia de un discurso crítico al sistema imperante.

Por otro lado, es menester realizar un análisis fccional de la novela porque se le ha leído alternativamente como un relato testimonial-antropológico; como una biografía resemantizada de Sarita Colonia Zambrano. En ambas lecturas está primando el aspecto sociológico y se está obviando toda inﬂuencia literaria. Es decir, se está dejando de lado todo el valor simbólico de la ficción.
Estudios sobre la estructura y el color en los textiles Paracas
Authors: Del Valle Cárdenas Aldo
Published: October 2020

Se presentan los diversos estudios hasta ahora realizados de los diseños y arte de los tejidos Paracas descubiertos en 1925, desde la arqueología, la semiótica y la historia del arte. Diversos autores se han acercado a la simbología, el orden de los colores y las tendencias estilísticas de los textiles, hace falta enfatizar suvalor como piezas de arte.
Juego con el concepto de “obra orgánica” en 5 metros de poemas, de Carlos Oquendo de Amat
Authors: León Mango Liz Fiorella
Published: October 2020

A través del análisis de 5 metros de poemas, de Carlos Oquendo de Amat, se plantea evidenciar un intento de emancipación de la poesía peruana con respecto de los valores formales tradicionales que encarnaban las ideas de perfección y de “progreso artístico”. Creemos que el poeta, basado en una poética expresiva y lúdica, problematizó el concepto de obra orgánica por medio de dos experimentos lúdicos: a) la fragmentación material de la obra de arte como si fuera un juguete; b) la mezcla de diversos estilos artísticos comprendidos en un mismo nivel cual si fueran piezas de juego desancladas de la historia y las individualidades.
Función de la música y la indumentaria como signos de la identidad andina en Diamantes y pedernales
Authors: Alcántara Silva Ynés V.
Published: October 2020

Las manifestaciones culturales del mundo andino tienen una importante expresión en la narrativa de José María Arguedas. En Diamantes y pedernales, la música actúa como un factor unificador y revitalizador de la cultura andina, para lo cual se articula con los principios de su cosmovisión. Es así que la música se realciona estréchamante con los seres de este universo. Así, los personajes, los instrumentos musicales, los rituales y las prácticas sociales y culturales comparten una interrelación e interinfluencia. Por otro lado, la indumentaria de la comunidad indígena distingue e identifica a los personajes de la novela y se asocia con determinados significados. Tanto la música con su función de revitalización del mundo andino y la indumentaria de los personajes contribuyen a afirmar la identidad de la comunidad indígena en esta novela.
El discurso metafórico en la poesía erótica de Carlos Germán Belli
Authors: Mautino Guillén Alejandro Giancarlo
Published: October 2020

En este artículo analizamos la función fundamental que tienen los elementos metafóricos en la construcción del discurso erótico en la poesía de Carlos Germán Belli. Desde nuestra perspectiva, las metáforas y los discursos deglutientes y vigilantes en su poética construyen una singular reflexión sobre la cotidianidad del acto erótico a través del cuerpo. Para tal propósito nos apoyamos en la neorretórica y la lingüística cognitiva para entender la relación entre pensamiento-lenguaje vinculados al discurso poético erótico en algunos poemas del autor de Sextinas y otros poemas (1970).
Vanguardia política y vanguardia artística en las revistas de Vicente Huidobro. El discurso polémico en Ombligo y Vital (1934, 1935)
Authors: Ibarlucía Rocío
Published: October 2020

Las revistas Ombligo y Vital, dirigidas por Vicente Huidobro entre 1934 y 1935, presentan un repertorio de discursos en torno de la Revolución Rusa, el movimiento obrero en EE. UU. y las políticas conservadoras chilenas, gracias al cual es posible redefinir la figura del poeta, generalmente encasillada en la vertiente artística de las vanguardias latinoamericanas. El artículo analiza las polémicas entabladas entre Huidobro e intelectuales chilenos, para lo cual apelamos a nociones provenientes de la teoría de la argumentación propuesta por Perelman (1989). Observamos una ridiculización de la argumentación política mediante comentarios irónicos que refuerzan la denuncia a las doctrinas de derecha. Estos órganos de difusión, entonces construyen una escritura sostenida en la ironía a fin de disputar un lugar privilegiado en el campo literario local, lo que obliga al propio Huidobro a revisar su proyecto creador y, en consecuencia, a restablecer los préstamos entre vanguardia artística y vanguardia política.
La literatura en la perspectiva de la ecocrítica
Authors: Camasca Edwin
Published: October 2020

El artículo aborda los fundamentos de la ecocrítica y su vínculo con el estudio de la literatura. El texto tiene por propósito explicar los principios, propuestas y objetivos de la ecocrítica, así como su contribución en la formación de una conciencia crítica acerca de los problemas relacionados con el medio ambiente. Desde la mirada de la ecocrítica, las obras literarias ilustran la existencia de graves problemas medioambientales, evidencian la acción del hombre en el proceso de la destrucción de la naturaleza, revelan la actitud utilitaria que caracteriza a la explotación de los recursos naturales y pone de relieve la falta de un verdadero compromiso del ser humano con su hábitat. Mediante una revisión de la literatura española e hispanoamericana, el artículo analiza las características de la relación hombre-naturaleza en el marco de la ecocrítica. En esa perspectiva, dicha relación resulta fundamental en la poesía de los pueblos nativos, tal como se expresa en la voz de los poetas mapuches.
Pharmacokinetics and bioavailability of liensinine in mouse blood by UPLC-MS/MS
Authors: Tong Shuhua , Zeng Yuqi , Ma Jianshe , Wen Congcong
Published: October 2020

Liensinine is a bisbenzyltetrahydroisoquinoline alkaloid extracted from lotus (Nelumbo nucifera GAERTNER., Nelumbonaceae), especially in its embryo loti “Lien Tze Hsin” (green embryo of mature seed). A rapid and simple UPLC-MS/MS method was developed to determine liensinine in mouse blood and its application to a pharmacokinetic study. The blood samples were preprocessed by protein precipitation using acetonitrile. Midazolam (internal standard, IS) and liensinine were gradient eluted by mobile phase of methanol and water (0.1% formic acid) in a Waters UPLC BEH C18 column. The multiple reaction monitoring of m/z 611.3 → 206.1 for liensinine and m/z 326.2 → 291.1 for IS with an electrospray ionization (ESI) source was used for quantitative detection. The calibration curve ranged from 0.5 to 400 ng/mL (r > 0.995). The accuracy ranged from 92.2 to 108.2%, the precision of intra-day and inter-day was less than 14%, and the matrix effect was between 100.0% and 109.6%, the recovery was better than 71.0%. The developed UPLC-MS/MS method was successfully used for a pharmacokinetic study of liensinine in mice after oral (5 mg/kg) and intravenous administration (1 mg/kg), and the absolute availability of liensinine was 1.8%.
New records and range extension of the recently reestablished Lamanonia ulei (Engl.) L.B. Sm. (Cunoniaceae): notes on taxonomy and conservation
Authors: Santos-Silva Fernanda , Cardoso Pedro Henrique , Zorzanelli João Paulo Fernandes , Cabral Andressa
Published: October 2020

We report new records of the recently reestablished Lamanonia ulei (Engl.) L.B.Sm. (Cunoniaceae) from southeastern Brazil. This species is currently known by only eight specimens from Minas Gerais, Rio de Janeiro, and São Paulo states. We present seven new records that include Espírito Santo state in the species distribution, and expand its north and east limits of occurrence. We also present a taxonomic description, photos, occurrence map, conservation status assessment of L. ulei, and an identification key for all the species of Lamanonia Vell. from Brazil.
Toxicological profile for arsenic
Authors:   United States, Agency for Toxic Substances and Disease Registry. Syracuse Research Corporation
Published: October 2020

A Toxicological Profile for Arsenic, Draft for Public Comment was released in September 2005. This edition supersedes any previously released draft or final profile. CAS#: 7440-38-2"
Teosofi Tariqa and Its Principles, Rituals, and Rationality as a Religious Movement
Authors: Huda M. Dimyati , Chamid Nur
Published: October 2020

This article seeks to reveal the principles, rituals, and rationality of a religious movement named Teosofi Tariqa. This Sufi order has existed in Indonesia since 1908. This research finds its importance on the basis of the fact that the Teosofi Tariqa offers different perspectives from other religious movements. It also becomes an interesting study in terms of religious conflict resolution in Indonesia. Using a qualitative approach, this research relies much on a number of data collecting instruments such as observations, interviews, and documentation. The Miles and Huberman versions are used to analyzing the data. The research finds that the Teosofi Tariqa in Surabaya promulgates tolerance and diversity principles towards other people regardless of their religions. As a Sufi order, the Teosofi Tariqa puts emphasis on mysticism and meditation as a means of submission, obedience, and servitude to the absolute and rational God. It also emphasizes the importance of community services.
Sufi Qur'ānic Exegesis and Theomorphic Anthropology
Authors: Cúrto Stephen
Published: October 2020

Of all the various ideological controversies in the history of Islamic thought, one of the most highly contentious areas are those surrounding the ontological nature of the Divine attributes (Ṣifāt Allah). Such questions surrounding God’s attributes, and what delineation, if any, is to be made between the nature of God in his Divine attributes and in his Being (Dhāt Allah) preoccupied some of the greatest classical participants in the ‘ilm al-kalām systematic theological disputation tradition. This study engages Qur’ānic paradigms of theomorphic anthropology and re-interrogations by Sufi thinkers. There is a rich debate within Islamic Scholarship on the nature of the Divine attributes, and their interrelationship, if any, with Banī Adam. Many of the mystical Sufi scholars, such as Ibn ‘Arabī, Mūlla Sadra, Nāṣir Khusraw, and Abū Ḥāmid al-Ghazālī all articulated onto-theological concepts in their writing that became known as Waḥdat al-Wujud, Tajallī Allah, Tajallī al-Nafs’ Nafs-e ‘Aql, and Nafs-e Kūl. This paper argues that the idea of Divine immanence articulated in concepts like ‘Tajallī al-Nafs’ is not a later retrojection onto Qur’ānic material. Rather it is the Qur’ānic material that exegeted with a meaningful and consistent hermeneutic resulted in their theosophical understandings.
Stimuli-Responsive Polymers Providing New Opportunities for Various Applications
Authors: KOÇAK Gökhan , TUNCER Cansel , BÜTÜN Vural
Published: October 2020

Stimuli-responsive polymers significantly change their physical or chemical properties when there is a small change in the conditions of their environments. Depending on the changes on conditions, they can self-assemble to form various nanosized structures having important usages in different fields. In this review, we report an analysis of some of the recent literatures on the basic subjects such as the architectures of different environmentally sensitive polymers, their classifications according to susceptibility and applications in various areas. During the last two decades, there have been great reports in the strategies for the preparation of novel stimuli-responsive polymers and/or polymeric materials which are suitable for various applications including materials science, nanotechnology, biotechnology, colloid and surface science, etc. In order to make this very broad polymer type more understandable to readers, basic concepts/topics are generally schematized. Furthermore, the strategies that can be followed in the production of these materials are tried to be given at a sufficient level.
UK participation at ICOLD 2019, Ottawa, Canada
Authors: Loughrey Sarah
Published: October 2020

The Canadian Dam Association hosted the International Commission on Large Dams’ (ICOLD) (2019) annual meeting. This paper collates updates on the ICOLD technical committees provided by the UK representatives along with updates on general ICOLD business as discussed at the general assembly meeting. Please note this report was prepared prior to the postponement of the Delhi 2020 ICOLD annual conference.
On-site testing of masonry shear walls strengthened with timber panels
Authors: Giongo Ivan , Rizzi Ermes , Riccadonna Daniele , Piazza Maurizio
Published: October 2020

The effectiveness of a method to strengthen/repair unreinforced masonry (URM) by using timber-based products was investigated through experimental in situ testing. The strategy consists of timber-based panels connected to the masonry by means of screw fasteners. URM piers obtained from a century-old building were subjected to in-plane semi-cyclic quasi-static loading in as-built, repaired and retrofitted configurations. The application of the reinforcement on previously damaged piers led to a notable increase in the in-plane capacity while the initial stiffness of the repaired specimens was found to be consistent with that of the specimens tested as-built. When applied to undamaged masonry, the retrofit system allowed an in-plane force 40% higher than the capacity of the unreinforced walls, with the initial stiffness comparable with that of the repaired specimens. Both repaired and retrofitted specimens exhibited remarkable displacement capacity (drift levels > 2.0%) and energy dissipation.
Experimental testing and analysis of the axial behaviour of intermeshed steel connections
Authors: McGetrick Patrick J. , Matis Pantelis , Martin Tony , Robinson Desmond , Laefer Debra F. , Al-Sabah Salam , Truong-Hong Linh , Huynh Minh Phuoc , Schultz Arturo E. , Le Jia-Liang , Shemshadian Mohammad E. , Labbane Ramzi
Published: October 2020

This paper presents the work carried out on a collaborative tripartite project between the USA, Republic of Ireland and Northern Ireland to create and investigate the design, development and testing of a new class of intermeshed steel connections (ISCs) that do not rely on field welding and minimise bolting, thus targeting the facilitation of fast disassembly of steel structures and material reuse. This research took advantage of fully automated, precise, advanced manufacturing cutting technologies (e.g. laser, waterjet and high-definition plasma cutting) to achieve a connection method in steel that previously was only possible in materials such as timber, with the potential to revolutionise the steel construction industry. The paper outlines the ongoing research work by the collaborative team, focusing on the design, fabrication, finite-element analysis (FEA) and scaled experimental testing of side ISCs for the flanges of open sections, which included the use of state-of-the-art digital image correlation technology for non-contact measurements. A simplified connection design procedure is presented based on yielding of the side plates. This design procedure is refined based on the results of experimental testing and FEA of the local axial behaviour of the flange connection, addressing stress concentrations in the flange, fabrication tolerances and material overstrength.
Web–flange distortional buckling of partially restrained CFS beams under uplift loading
Authors: Chen Zhenlei , Zhao Juan , Li Long-yuan
Published: October 2020

Cold-formed steel members are usually used as purlins in buildings to support roof cladding and thus they can be treated as beams restrained fully or partially in the lateral and torsional directions. However, when these beams are subjected to wind suction loading, their free flange is in compression, which may cause web–flange distortional buckling (WFDB). This paper presents an analytical study on the WFDB of zed-section purlins when subjected to uplift bending. A simplified model is proposed to describe the WFDB of partially restrained purlins, from which the formula for calculating the critical stress of the WFDB is derived. The present model is validated by the results obtained from the finite strip analysis.
Modelling the influence of steel structure compartment geometry on travelling fires
Authors: Charlier Marion , Gamba Antonio , Dai Xu , Welch Stephen , Vassart Olivier , Franssen Jean-Marc
Published: October 2020

The response of structures exposed to fire is highly dependent on the type of fire that occurs, which is in turn very dependent on the compartment geometry. In a European research project, computational fluid dynamics simulations were carried out to analyse the influence of compartment geometry and the interaction with representative fuel loads to explore the conditions leading to the development of a travelling fire. The influence observed of ceiling height, crib spacing and opening geometry in controlling spread rates tended to confirm the possibility of predicting the occurrence, or not, of a travelling fire. The results of one analysis were then used to perform a non-linear thermo-mechanical analysis of a steel structure. It was possible to use the radiative intensities and gas temperatures obtained with a computational fluid dynamics model to calculate with a finite-element model the temperatures in structural elements located in the compartment, and to evaluate the structural behaviour of a frame made of these elements. This paper therefore highlights the effect of building design specifications on the temperature development and on the resulting mechanical behaviour of a steel structure where the travelling nature of a fire has been considered comprehensively.
A waste heat recovery strategy and its deployment: an integrated steelworks case study
Authors: Giles Anthony , Williams Chris , Pugh Daniel , Bowen Phil , Marsh Richard , O'Doherty Tim
Published: October 2020

Steelmaking is energy intensive, with manufacturing facilities representing some of the biggest point-source carbon dioxide (CO2) emitters in the UK. Efficiency improvements are essential with rising energy costs, driving significant investment from the UK iron and steel sector. However, the industry still finds it difficult to justify waste heat recovery (WHR) projects, as individual schemes incorporating waste heat capture and an end-use for the waste heat often incur high capital costs, resulting in long payback times. This paper describes the conceptual and numerical development of a strategy for the deployment of WHR using a large integrated steel works as a case study. An existing asset was utilised to link individual waste heat schemes together with a single end-user; thereby reducing the capital requirement for each subsequent project. The proposed strategy and its development is discussed, followed by the resultant carbon dioxide and energy savings (estimated to be 2.3 Mt and equivalent to £45 million), over the 6-year period since its implementation.
New‐onset musicogenic epilepsy after temporal lobe epilepsy surgery
Authors: Pejović Aleksa T. , Vojvodić Nikola , Djukić Tijana , Kovačević Maša , Ristić Aleksandar J. , Baščarević Vladimir , Sokić Dragoslav
Published: October 2020

Musicogenic epilepsy is a reflex epilepsy provoked by listening to or playing music. The epileptogenic network involves temporal regions, usually mesiotemporal structures. We present a 31‐year‐old female patient who experienced musicogenic seizures after a right temporal lobectomy with amygdalohippocampectomy that was performed in order to treat preexisting right mesio‐temporal epilepsy.
Additional clinical value of voxel‐based morphometric MRI post‐processing for MRI‐negative epilepsies: a prospective study
Authors: El Tahry Riëm , Santos Susana Ferrao , Vrielynck Pascal , de Tourtchaninoff Marianne , Duprez Thierry , Vaz Geraldo Ribeiro , Raftopoulos Christian , Choi Joon Yul , Wang Zhong Irene
Published: October 2020

Aims: Magnetic resonance imaging is of paramount importance in the presurgical evaluation of drug resistant epilepsy. Detection of a potentially epileptogenic lesion significantly improves seizure outcome after surgery. To optimize the detection of subtle lesions, MRI post‐processing techniques may be of essential help.

Methods: In this study, we aimed to evaluate the detection rate of the voxel‐based morphometric analysis program (MAP) in a prospective trial. We aimed to study the MAP+ findings in terms of their clinical value in the decision‐making process of the presurgical evaluation.

Results: We included, prospectively, 21 patients who had negative MRI by visual analysis. In a first step, results of the conventional non‐invasive presurgical evaluation were discussed, blinded to the MAP results, in multidisciplinary patient management conferences to determine the possible seizure onset zone and to set surgical or invasive evaluation plans. Thereafter, MAP results were presented, and the change of initial clinical plan was recorded. All MAP detections were reaffirmed by a neuroradiologist with epilepsy expertise. For the 21 patients included, mean age at the time of patient management conference was 26 years (SD 15 +/‐ years, range: 5–54 years). In total, 4/21 had temporal lobe epilepsy and 17/21 had extra‐temporal lobe epilepsy. MAP was positive in 10/21 (47%) patients and in 6/10 (60%) a diagnosis of focal cortical dysplasia was confirmed after neuroradiologist review, corresponding to a 28% detection rate. MAP+ findings had a clear impact on the initial management in 7/10 patients (7/21, 33% of all patients), which included an adaptation of the intracranial EEG plan (6/7 patients), or the decision to proceed directly to surgery (1/7 patients).

Conclusion: MRI post‐processing using the MAP method yielded an increased detection rate of 28% for subtle dysplastic lesions in a prospective cohort of MRI‐negative patients, indicating its potential value in epilepsy presurgical evaluation.
Gelastic seizures: a retrospective study in five tertiary hospital centres
Authors: Loução de Amorim Isabel , Pereira Cristina , Sequeira João , Rocha Helena , Peralta Ana Rita , Rego Ricardo , Bentes Carla , Bento Conceição , Sales Francisco , Robalo Conceição , Pimentel José
Published: October 2020

Aim: This study aimed to characterize, clinically and neurophysiologically, a series of patients with gelastic seizures (GS), including both adults and children.

Methods: We retrospectively collected patients with GS from epilepsy clinics of five tertiary hospital centres within a single country. Patients were selected through relatives’/caregivers’ descriptions, home video and/or video‐EEG monitoring. GS were identified through ictal semiology.

Results: Thirty‐five patients were enrolled; 62.9% had initial GS in infancy, 14.3% in adolescence and 22.8% at adult age. Twenty‐six had abnormal MRI: eight presented with hypothalamic hamartoma (HH) and 16 non‐HH lesions that included different structural aetiologies and genetic, metabolic and immune aetiologies. All patients with HH had their first GS in infancy or adolescence. For the remaining aetiologies, GS started in infancy in 59.3%, in adolescence in 11.1% and at adult age in 29.6%. Video‐EEG data was available for analysis in 11 patients, including seven patients with a non‐HH MRI lesion. The ictal onset topography on scalp video‐EEG was usually concordant with the MRI lesion (in 6/7 patients) and the most frequent ictal onset was fronto‐temporal. In two patients, both video‐EEG and MRI suggested a parietal and occipital epileptogenic zone.

Conclusion: Aetiologies and patterns of affected topography unrelated to HH are common in patients with GS, and all age groups may manifest with this type of ictal semiology. This ictal manifestation has no lateralizing value and, despite a clear preponderance for hypothalamic, frontal and temporal lobe origins, other brain areas, namely the parietal and occipital lobes, should be considered.
GAT‐1 (rs2697153) and GAT‐3 (rs2272400) polymorphisms are associated with febrile seizures and temporal lobe epilepsy
Authors: Schijns Olaf EMG. , Bisschop Jeroen , Rijkers Kim , Dings Jim , Vanherle Sabina , Lindsey Patrick , Smeets Hubert JM. , Hoogland Govert
Published: October 2020

Aim: The purpose of this study was to determine a possible association between two GABA transporter (GAT) single‐nucleotide polymorphisms (SNPs), rs2697153 G>A in SLC6A1 (GAT‐1) and rs2272400 C>T in SLC6A11 (GAT ‐3), and drug‐resistant temporal lobe epilepsy (TLE).

Methods: DNA was isolated from 138 TLE patients (from the neocortex) and 94 non‐epileptic controls (from blood/buccal swaps), and amplified by polymerase chain reaction and subjected to restriction fragment length polymorphism assays. A subgroup of patients with a positive history of febrile seizures (FS+) and traumatic brain injury (TBI+) were investigated in a separate analysis. P values were obtained using the Chi‐Square test and Fishers exact test.

Results: The GAT‐1 SNP was different between patients and controls (p<0.05); the AA genotype was observed in 40% of the cases vs 23% of the controls (p<0.05). Thirty‐one patients were FS+ and the GAT‐3 CT genotype was observed significantly more frequently in the FS+ group (14%) than in the FS‐ group (1%; p<0.01). Thirteen patients were TBI+, and genotyping for GAT‐1 and GAT‐3 in these patients did not result in statistical differences between TBI+ and TBI‐ groups.

Conclusions: The findings suggest that TLE is associated with GAT‐1 and GAT‐3 SNPs. More specifically, GAT‐3 c1572T seems to be associated with TLE in patients with FS+. However, the pathophysiological consequences of these SNPs remain to be elucidated.
The effect of oral administration of monosodium glutamate on epileptogenesis in infant rats
Authors: Demirkapu Mahluga Jafarova , Yananlı Hasan Raci , Akşahin Elif , Karabiber Ceren , Günay Pınar , Kekilli Arda , Topkara Betilay
Published: October 2020

Aim: Glutamate is an excitatory neurotransmitter that is widely distributed throughout the brain. An increase in glutamate concentration or sensitivity of glutamate receptors triggers neurodegenerative diseases, epilepsy in particular. Monosodium glutamate is a substance added to foods to enhance flavour. We investigated the effect of monosodium glutamate on epileptogenesis, as well asheight and weight, in rats that were just weaned.

Methods: Twenty‐four male and female 21‐day‐old Wistar Albino rats were divided into two groups: one with monosodium glutamate added to the drinking water, and a control in which NaCl was added to the drinking water. The electrical stimulation threshold values were determined in animals to which the hippocampal kindling process was applied, and the stimulations at these threshold values were invariably applied to the animals until they were kindled.

Results: The electrical stimulation threshold values of the monosodium glutamate group did not statistically change, whereas the number of required stimulations for kindled rats was significantly lower compared with the control group.

Conclusion: These results reveal that long‐term oral administration of glutamate salts causes an increase in excitability in the central nervous system during ontogenetic development.
Introduction
Authors: Kenworthy Nora , Thomas Lynn M. , Crane Johanna
Published: October 2020

n/a
СЕМЬЯ И ЖИЗНЕННЫЕ ПРОЕКТЫ РОССИЙСКОЙ МОЛОДЕЖИ В ЛОГИКЕ ПАРАДОКСАЛЬНОГО АНАЛИЗА
Authors: Верещагина Анна Владимировна , Герасимов Максим Васильевич
Published: October 2020

Цель исследования. Жизненный проекты молодежи как предмет социологической рефлексии представляют чрезвычайный интерес для социологии. Молодежь стоит на «пороге» будущего и еще только конструирует его образ. Этот образ будущего является системообразующим в пространстве конструирования жизненного мира молодежью, но в современной реальности он утратил четкие очертания, а сам характер жизненного проектирования перестал носить линейный и целостный характер.
РУССКИЙ ЯЗЫК В СОВРЕМЕННОМ КИТАЕ (ОПЫТ ПРЕПОДАВАНИЯ В ЧАНЧУНЬСКОМ ИНЖЕНЕРНО-ТЕХНОЛОГИЧЕСКОМ ИНСТИТУТЕ)
Authors: Ван Лэй , Бутенко Людмила Ивановна
Published: October 2020

Перспективное сотрудничество Российской Федерации и Китайской Народной Республики в области образования способствует увеличению спроса на специалистов со знанием русского языка и постоянному росту интереса к его изучению, в том числе в среде студентов китайских вузов.