bluuebunny/crossref_metadata_2025 huggingface dataset:
UNSUAL BEHAVIOR OF COLLOID BREAST CARCINOMA: CASE REPORT
Authors: Jacome Anna Carolina Pereira , Silva Alice Morais de Castro , Correa Daniela Beggiato , Bernucci Neto Ingrid , Bellini Patrícia Aguiar
Published: January 2022

Introduction : Colloid breast carcinoma is a rare variant of invasive ductal carcinoma, representing 1% to 6% of the cases. It is characterized by rich deposition of extracellular mucin upon anatomopathological analysis (AP). In general, it has positive hormone receptors, inclusion in the Luminal A molecular subtype, and an epidemiological profile of older women. Its behavior is usually indolent, associated with a low grade and favourable prognosis. It is unlikely to infiltrate axillary lymph nodes or be associated with metastatic potential. We present a case report of a patient with invasive colloid carcinoma of the breast associated with ductal carcinoma in situ (DCIS) and early axillary recurrence of a colloid pattern, contesting the mild behavior that is the gold standard in the literature. Case report: A 63-year-old patient, without relevant risk factors, was admitted due to a palpable nodule in the upper outer quadrant (UOQ) of her left breast (LB). Radiological exams showed a nodular lesion of 15x16x10 mm, heterogeneous and non-circumscribed associated with microcalcifications, with core biopsy showing colloid carcinoma. The axillae were clinically and radiologically negative. She underwent a sentinel lymph node biopsy and lumpectomy. AP results showed invasive colloid carcinoma, grade 2, measuring 1.7 cm, associated with cribiform DCIS occupying 20% of the total area of the neoplasia, free margins and three negative sentinel lymph nodes. Immunohistochemistry was compatible with Luminal A. Treatment with radiotherapy and the use of tamoxifen followed. During follow-up, in July 2020, a physical examination showed thickening in the UOQ and a hardened palpable lymph node on the left. Routine examinations showed a complex nodule compatible with clinical thickening in the UOQ and grouped and heterogeneous microcalcifications in the retroareollar region of the LB, in addition to axillary lymphadenopathy with asymmetric cortical thickening at ipsilateral level I. For better elucidation, breast magnetic resonance imaging was requested, which showed areas suggestive of fibrocicatrial changes and suspicious-looking lymph node enlargement on the left. Fine-needle aspiration biopsy (FNAB) guided by ultrasound was performed, compatible with positivity for atypical cells. Thereby, a new surgical approach was performed: mastectomy and level I axillary node dissection on the left. AP was compatible with 0.6mm DCIS associated with intraductal papilloma without atypia of LB and 1 in 6 lymph nodes, positive for diffuse infiltration by colloid pattern carcinoma. Today, the patient is being followed up, using anastrozole, without oncological changes in other follow-up exams. Cases that deviate from the standard in literature, such as the exposed surprisingly aggressive behavior of a rare variant, should be reported to encourage discussions about adequate approach and treatment.
VALIDATION OF IMMUNOPHENOTYPING BY FLOW CYTOMETRY IN THE INVESTIGATION OF DIAGNOSTIC AND PROGNOSTIC MARKERS FOR BREAST CANCER
Authors: Vieira Daniella Serafin Couto , Wopereis Sandro , Walter Laura Otto , Silva Maria Claudia Santos da
Published: January 2022

Introduction: Due to the high prevalence of breast cancer, it has a major financial impact on health systems. Currently, the diagnosis is made by morphological and immunohistochemical analysis (IHC). However, this methodology has some limitations. Therefore, methodologies capable of rapid and safe detection of tumor cells are needed, which can assist those already in use. Objectives: To validate immunophenotyping by flow cytometry (FC) in the investigation of diagnostic and prognostic markers for breast cancer; and to investigate lymphocytes subtypes infiltrated in the tumor and their relationship with tumor development. Methods: 52 breast tumor samples were sectioned and macerated in phosphatesaline buffer and stained with antibodies against estradiol (RE), progesterone (RP), HER2, Ki67, CD3, CD4, CD8 and CD45 receptors and analyzed by FC. All results were compared with IHC (reference method) in relation to sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV), except for Ki67, where bias was compared between methodologies and correlation between lymphocyte subtypes and tumor characteristics. Results: The comparison of the FC with the IHC for each marker presented the RE analysis (sensitivity: 75%, specificity: 90%, PPV: 96.7%, VPN: 47.4%); PR analysis (sensitivity: 72%, specificity: 70%, PPV: 79.3%, VPN: 60.8%); analysis of HER2 (sensitivity: 80%, specificity: 90.2%, PPV: 66.7%, VPN: 94.9%). The analysis of Ki67 by FC was shown to be equivalent to IHC, with the advantage of not having an observational bias. No correlations were observed between the molecular subtype intratumor lymphocyte population profile and the tumor histological grade. Conclusion: The results show the FC’s ability to safely and quickly detect breast cancer markers used in clinical practice. It is believed that the use of FC, in conjunction with morphological analysis and IHC, can overcome the individual limitations of each of the methodologies and provide reliable results in a faster and more efficient way, which will result in faster diagnoses and more accurate prognoses, directly benefiting patients.
Modulation of atrial natriuretic peptide receptors in ovarian folliculogenesis
Authors: Sung Zoo Kim
Published: January 2022

Specific receptors for atrial natriuretic peptide (ANP) located in intra-ovarian tissues are suggested to be involved in ovarian functions such as oocyte maturation and follicle development. However, the characteristics and modulation of its receptor in relation to ovarian folliculogenesis are not well defined. This study examined the properties of ANP receptors in the ovary using quantitative receptor autoradiography. In the pig ovary, the highest binding sites for 125I-ANP(1-28) were localized in the granulosa cell layer of the follicles as well as cumulus oophorous. The binding sites for 125I-ANP(1-28) on theca layer of the ovarian follicles were mainly localized in the external layer, but none was observed in the internal layer. Specific binding of 125I-ANP(1-28) was not found clearly in atretic follicles. In the corpus luteum, the binding site was not observed. Analysis of the competitive inhibition of the binding of 125I-ANP(1-28) to the granulosa and theca externa layers in various preovulatory follicles by increasing concentrations of unlabeled ANP(1-28) was consistent with a single high affinity for 125I-ANP(1-28). The maximal binding capacities of 125I-ANP(1-28) in granulosa layer were significantly increased in proportion to the development of ovarian follicles. However, no significant difference of binding capacities of 125I-ANP(1-28) was observed in theca externa layer. The binding affinities of 125I-ANP(1-28) in granulosa and theca externa layers were not different from each other. Especially, the correlation between specific binding of 125I-ANP(1-28) and follicle diameter. A significant correlation was revealed between specific binding of 125I-ANP(1-28) and follicle diameter (R = 0.88, p < 0.0001) in granulosa layer, however, less relationship was detected in theca externa layer (R = 0.50, p < 0.0001). Therefore, these results indicate that the biological ANP receptors exist in granulosa and the theca externa layers of the pig ovary, and suggest that the ANP receptors in granulosa layer may be related to the regulatory function of the ovarian follicullogenesis including oocyte maturation.
Pengembangan Perangkat Pembelajaran Model PBL Berbantuan Simulasi PhET untuk Meningkatkan Kemampuan Berpikir Tingkat Tinggi
Authors:   Prodi Pendidikan Fisika, Jurusan Pendidikan MIPA, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Mataram, Gunawan Arman Rizal , Hikmawati Hikmawati ,   Prodi Pendidikan Fisika, Jurusan Pendidikan MIPA, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Mataram, Gunada I Wayan ,   Prodi Pendidikan Fisika, Jurusan Pendidikan MIPA, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Mataram, Susilawati Susilawati ,   Prodi Pendidikan Fisika, Jurusan Pendidikan MIPA, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Mataram
Published: January 2022

This development research aims to produce a product in the form of a physics learning device with a problem based learning model on Momentum and Impulse material to improve students' higher-order thinking skills. The type of research is Research and Development (R&D) with a 4D model consisting of Define, Design, Develop, and Disseminate. The products developed are syllabus, online learning implementation plans, student worksheets equipped with PhET simulation instructions, and higher order thinking ability test instruments. Product validity was assessed by five validators with Likert scale analysis. Furthermore, the effectiveness of the device is determined from a limited trial to get the N-gain value. The results of the study based on the validator's assessment showed that the overall device developed had an average value of above 3.00 in the good category, then the average N-gain test results obtained a value of 0.34 in the medium category. Thus, it can be concluded that the development of problem based learning physics learning tools on Momentum and Impulse material is valid, and effective for improving students' higher order thinking skills.
Hubungan Aktivitas Fisik Dengan Indeks Massa Tubuh Pada Anak Di Daerah Kampung Nelayan Pesisir Pantai Kenjeran
Authors:   Universitas Negeri Surabaya, Prasetio Bayu , Himawan Susanto Indra ,   Universitas Negeri Surabaya
Published: January 2022

The prevalence of child obesity worldwide has increased rapidly over the past 3 decades. The danger that threatens children is not only overweight or obesity but also malnutrition is still a disease that attacks children under five in developing countries. This study aims to determine whether there is a relationship between physical activity and body mass index of children in the coastal fishing village of Kenjeran, Surabaya City. This research was conducted using cross sectional method. The research, which was conducted in the coastal fishing village of Kenjeran, Surabaya, used the research subjects were 105 children in the area. Purposive sampling technique is a technique used for sampling. In this study, the PAQ-C questionnaire was used as an instrument to measure physical activity while measuring body mass index consisting of height and weight used microtoise instruments and digital scales. The data analysis technique used Spearman rank correlation with a significance level of < 0.05. The results of the coefficient correlation analysis are - 0.41 and also get a significance result of 0.680. Significant result > 0.05. The conclusion from the results of this study is that there is no significant relationship between physical activity variables and body mass index of children in the coastal fishing village of Kenjeran, Surabaya City.
PENGUKURAN KINERJA SUPPLY CHAIN MENGGUNAKAN SUPPLY CHAIN OPERATION REFERENCES (SCOR) DI PT. RAVANA JAYA
Authors: Fikriyah Samrotul , Leksono Eko Budi , Widyaningrum Dzakiyah
Published: January 2022

PT. Ravana Jaya merupakan perusahaan yang bergerak dibidang general contractor. Perusahaan yang menerapkan system make to order ini memproduksi berbagai macam olahan baja. Dalam menjalankan aktivitas rantai pasoknya, PT. Ravana Jaya sering mengalami masalah. Pada proses pengadaan, perusahaan ini sering mengalami keterlambatan raw material sehingga berpengaruh pada pada keterlambatan penyelesaian order sesuai dengan jadwal yang telah ditentukan. Selain itu juga belum adanya indikator-indikator penilaian kinerja rantai pasok yang disajikan dalam Key Performance Indicator (KPI) di PT. Ravana Jaya. Oleh karena itu, penelitian ini dilakukan untuk merancang system pengukuran kinerja supply chain menggunakan Supply Chain Opertion References (SCOR). Dalam penelitian ini dibahas mengenai pengukuran kinerja supply chain menggunakan Supply Chain Operation Referece (SCOR). Pengukuran dilakukan berdasarkan 5 proses inti (plan, source, make, deliver, dan return), dan beberapa dimensi (reliability,responsiveness, flexibility, coet, dan Asset). Beberapa dimensi tersebut akan didekomposisi dalam beberapa Key Performance Indikator (KPI). Selain itu juga dilakukan pembobotan tiap proses inti, dimensi dan KPI dengan menggunakan Analytical Hierarchy Process. Sedangakan normalisasi snorm de bour digunakanuntuk menyamakan nilai KPI. Pengukuran kinerja supply chain di PT. Ravana Jaya ini diperoleh 24 KPI. Pegukuran kinerja dilakukan pada project yang ditangani PT. Ravana Jaya pada tahun 2018 dengan total 4 project. Adapun nilai kinerja supply chain perusahaan di tahun 2018 pada project 1 adalah 61,91 (average), project 2 sebesar 61,21 (average), project 3 sebesar 54,09 (average), dan pada project 4 sebesar 75,62 (good)
Identifikasi Resiko Kegagalan Proses Penyebab Terjadinya Cacat Produk dengan Metode FMEA-SAW
Authors: Basuki Ari , Chusnayaini Ichdal
Published: January 2022

Tujuan dari penelitian ini yaitu untuk mengetahui prioritas resiko terjadinya kegagalan proses yang berdampak pada terjadinya cacat produk di suatu perusahaan. Metode yang digunakan pada penelitian ini yaitu integrasi metode FMEA dengan metode SAW. Metode SAW digunakan untuk memberikan bobot pada faktor severity, occurance dan detection yang terdapat pada metode FMEA. Penelitian ini menggunakan studi kasus di PT. XYZ. PT. XYZ merupakan perusahaan manufaktur yang memproduksi kayu lapis (Plywood) dengan pasar ekspor. Berdasarkan data penelitian awal, diketahui perusahaan ini hanya mampu menghasilkan produk dengan kualitas ekspor sebesar 88,3%, sisanya yaitu berupa produk kualitas lokal dan scrap. Oleh karena itu, dengan menggunakan metode FMEA-SAW ingin diketahui jenis kegagalan proses yang beresiko menyebabkan terjadinya produk cacat di PT.XYZ. Hasilnya yaitu peringkat tiga teratas sebagai penyebab terjadinya cacat produk adalah hasil potongan genjang merupakan jenis kegagalan yang menempati rangking paling atas sebagai penyebab terjadinya cacat produk, disusul dengan terjadinya kegagalan yang berupa bahan input yang terlalu lebar, dan kegagalan hasil yang tidak bisa menyatu dengan sempurna sebagai penyebab kegagalan yang menempati peringkat ketiga.
Dampak Penerapan Rantai Pasokan Berkelanjutan Terhadap Keunggulan Kompetitif Pada UMKM Konveksi di Desa Nogotirto
Authors: Maisaroh Maisaroh
Published: January 2022

Penelitian ini adalah penelitian kualitatif deskriptif, untuk menganalisis penerapan manajemen rantai pasokan berkelanjutan, dan dampaknya terhadap pencapaian keunggulan kompetitif industri konveksi di Dusun Mlangi Sawahan Nogotirto. Dengan menggunakan responden para pelaku yang terlibat dalam manajemen rantai pasokan industri konveksi di Desa Sawahan Nogotirto, peneliti mencoba menganalisis bagaimana pola dan penerapan manajemen rantai pasokan berkelanjutan serta  dampaknya terhadap pencapaian keunggulan kompetitif. Hasil penelitian menunjukkan bahwa pola manajemen rantai pasokan yang terbangun pada industri konveksi di Mlangi Sawahan Nogotirto melibatkan supplier utama, supplier perantara, industri konveksi,  pedagang besar dan eceran, dan onsumen akhir.  Dalam prakteknya, manajemen rantai pasokan juga sudah terintegrasi, baik secara aliran produk, aliran dana, maupun aliran informasinya, dari hulu ke hilir. Industri konveksi di Nogotirto juga sudah menerapkan manajemen rantai pasokan berkelanjutan serta berdampak positif terhadap keunggulan kompetitif, Industri konveksi di Nogotirto saat ini  market leader produk di beberapa lokasi pemasaran, dan kualitas produk yang lebih baik dibanding kualitas produk konveksi dari wilayah lain.  Disamping itu juga delivery dependability tercapai karena kedekatan lokasi industri dengan supplier perantara dan dengan pedagang besar/eceran.
DEVELOPING THE ELECTRONIC BOOK USING AUTORUN PRO ENTERPRISE APPLICATION FOR VIRTUAL SPEAKING CLASS AT KOKSANGA SCHOOL THAILAND
Authors: Wulandari Retno , Paulina Paulina
Published: January 2022

The aim of the research is to develop an electronic book of learning speaking for the fourth grade of Koksanga primary school Thailand that is conducted virtually. The method used in this research is Research and Development method with the ADDIE model. It includes five phases: students’ need analysis, designing the prototype, developing the product, implementing the product, and evaluating the product. The instruments used are interviews, expert judgment rubric, and summative test scores conducted before and after the implementation. The results show that the e-book media has a very valid category both from material suitability in the score 87,78 and physical design suitability in the score 77,78. Moreover, the difference in students’ scores before and after the implementation of the e-book shows significant improvement from the mean score of 52,7 in the pre-test to 75,3 in the post-test, which is the improvement is 22,6. Therefore, it means that the electronic book is suitable for the fourth-grade primary students in improving their speaking skills.
THE USE OF CONSTRUCTIONISM TO DEVELOP STUDENTS’ COMMUNICATION SKILLS THROUGH A SHARE LEARNING PROCESS
Authors: Yostasarn Warapon , Najah Shofiyatul , Simpol Wanida
Published: January 2022

The objectives of this study were (1) to develop English learning through a SHARE learning process based on Constructionism theory to develop achievement with an efficiency of 75/75, (2) to compare the students’ achievement between before learning and after learning, and (3) to compare the students’ attitude towards English learning through a SHARE learning process between before learning and after learning. For the research tools, the researcher used 10 lesson plans followed a SHARE learning process of Constructionism theory, communication assessments for learning English for communication, and the evaluation of students’ attitude towards English learning a SHARE learning process based on Constructionism theory. The results showed that (1) the development of English learning through a SHARE learning process had an efficiency of 82.15/83.21, (2) the students’ communication development after using English learning through a SHARE learning process based on Constructionism theory was higher than before statistically at the .05 level of significance, and (3) students’ attitude toward English learning was very satisfied.
An Evaluation of Clinical Learning Experience among Fourth-year Nursing Students of Nueva Ecija University of Science and Technology
Authors: Rivera George M. , Eugenio Thea Irise M. , Bendiola Romar M. , Esguerra Marie Denise M. , Quetua Kelvin Mark P. , Paras Danylen Felyze G. , Santiago Leinus Karl P. , Ocampo Divina B. , Catabona Zuzette B.
Published: January 2022

The clinical learning environment is an essential component of nursing education as it allows students to integrate theory into clinical practice. However, it is considered a critical factor as it may or may not help the student nurses grow and expand their knowledge, skills, and professional attitude. As such, this study described the clinical learning experience of the fourth-year nursing students of Nueva Ecija University of Science and Technology examining the underlying factors that influence the entire learning experience. The study utilized a descriptive – quantitative correlational design and total enumeration as the sampling procedure. The result showed that most of the respondents were in the early adulthood; female; monthly family income is 5,001-10,000, and preferred working in base hospital, operating room; and preferred the morning shift. The core competencies in which the respondents showed enhanced performance and aptitude were legal responsibility, ethico-moral responsibility, and collaboration and team work. The lowest, on the other hand, were personal and professional development, quality improvement, safe and quality nursing care, and research. A significant relationship between the actual age and safe and quality nursing and communication core competencies. A proposed action plan was devised for student nurses to strengthen their research competency.
Midwifery Care for Postpartum Mothers and Breastfeeding for Mrs. N In Dealing With Breast Milk is not yet Smooth
Authors: Nudelis Wilda , Yuliani Diah Atmarina
Published: January 2022

The postpartum period starts from 2 hours after the birth of the placenta until 6 weeks (42 days) after that. Puerperium is a period of recovery, starting from the completion of labor until the uterine devices return to their original state as before pregnancy. Katuk leaves contain compounds that can stimulate the hormone prolactin so that breast milk increases. One of the efforts to increase breast milk is to improve the quality of foods that have a direct effect on milk production, such as green vegetables, katuk leaves, sweet potato leaves, papaya leaves and so on. Katuk leaves contain almost 7% protein and 19% crude fiber, vitamin K, pro-vitamin A (beta-carotene, vitamins B and C. The minerals contained are calcium (2.8%) iron, potassium, phosphorus and magnesium. To find out the application of consuming katuk leaves can launch Mother's Milk. This scientific paper uses a method, namely a case study report using a descriptive method, the location at the residence of Mrs. N Gintung Agung Village, Lambur RT 03 RW 01 Kec. Mrebet Purbalingga Regency. The subject of the case study was the 5th day postpartum mother, namely Mrs. N with a little milk. The case study time is on March 23, 2021. Data collection techniques include interviews and secondary studies including documentation and literature studies. Mother's general condition was good, after consuming katuk leaves, Mother's Milk (ASI) increased. Giving katuk leaves is effective to increase breast milk for nursing mothers.
Development of Diabetes Education on Online-based Application: Telemondia
Authors: Isworo Atyanti , Ramadhani Yogi , Anam Akhyarul , Ekowati Wahyu , Azalia Ariesta Salwa
Published: January 2022

During the Covid 19 pandemic, a safe, efficient and effective educational method for diabetes patients is needed. Currently, an online-based education has developed, but this education is one-way, so the monitoring process is not getting enough attention. For this reason, it is necessary to develop online-based education in two directions so that there is interaction between patients, families and health workers. The purpose of this study is to develop a two-way online application-based education. The research method is research and development design. In the first phase, an online-based education development will be carried out with stages of design activities, validation and application acceptance testing. The results showed that an online application-based educational prototype named Telemondia had been composed and was validated by two diabetes education experts and two IT (Information Technology) experts. The following results from expert validation show the average aspect of ease of use of application is 90%; content clarity is 96.87%;  aesthetic is 84.75%; instructional quality is 87.5; and feedback quality is 85.42% , with an average overall aspects of 87.87%. This shows that Telemondia is very feasible to use. Furthermore, in the acceptance test for 25 diabetic patients, the results of this acceptance test show ease of use of application is 92%; content clarity is 93%;  aesthetic is 84%; instructional quality is 87; and feedback quality is 86%. The average overall aspect is 88.11%, which means that Telemondia can be accepted by patients. Further development will be made to add features that allow recording audio and video.
The Effect of Giving Religious Coping Handbook Therapy on Stress and Anxiety in Final Year Students of the Bachelor of Nursing Study Program at Muhammadiyah University of Purwokerto
Authors: Prapti Uci Yuning , Nurjanah Siti
Published: January 2022

Obstacles in writing a thesis can make students experience stress, anxiety, low self-esteem, frustration, loss of motivation, and delaying writing a thesis and some even decide not to finish their thesis. Coping mechanism is a way of dealing with stress and anxiety by deceiving oneself. Religious coping is one way to deal with stress with a religious approach. The aim of this research is to determine the effect of giving religious coping handbook therapy on stress and anxiety in final year students of the Bachelor of Nursing Study Program at Muhammadiyah University of Purwokerto. This study is a pre-experimental study with a one group pretest-posttest design. Purposive sampling technique with a total of 23 respondents according to the inclusion and exclusion criteria. The research instrument used the DASS and IROPE questionnaire. Data analysis using Wilcoxon test. The results showed that the stress of students before being given therapy had an average score of 35.57 and after therapy had an average score of 6.61. Anxiety of students before being given therapy has an average score of 31.91 and after being given therapy has an average score of 4.17. There is an effect of giving religious coping handbook therapy to stress and anxiety in final year students of the Bachelor of Nursing Study Program at Muhammadiyah University of Purwokerto (p value: 0.0001). There was a decrease in stress and anxiety scores after being given religious coping handbook therapy.
Cross Sectional Study : The Relationship Between Online Learning Media with the Knowledge of Cardiopulmory Resuscition Skill of Nursing Students
Authors: Rismawati Rismawati , Hikmawati Isna
Published: January 2022

The Covid-19 pandemic has affected 215 countries in the world and colleges are demanded to hold the online learning process which becomes one of the efforts to convey knowledge about Cardioplumonary Resuscitation skill to the students. The purpose of this research was to find out the correlation between online learning media and the knowledge of Cardioplumonary Resusctation skill on Nursing Students of Universitas Muhammadiyah Purwokerto. This was descriptive correlation research with cross-sectional approach that was conducted in the Faculty of Health Science in January 2021. The samples were taken using proportional startifed random sampling technique which resulted in 38 respondents. The test that was done was the statistik chi-squere test. The results of this research showed that the most implemented learning media included Youtube with 15 respondents (39.5%), Zoom with 13 respondents (34.2%), and Zoom+Youtube with 10 respondents (26.3%). The results also showed that 57.9% of the respondents had low knowledge of Cardioplumonary Resuscitation skills and 42.1% han a deep knowledge of Cardioplumonary Resuscitation skills. Meanwhile, the Chi-square test showed there was a correlation between online learning media and the knowledge of Cardioplumonary Resuscitation skills with p-value of 0.002. Therewas a correlation between online learning media and the knowledge of Cardioplumonary Resuscitation skills among Nursing students of Universitas Muhammadiyah Purwokerto.
The Effect of Communication, Information, Education on the Knowledge Level of Acceptors about Side Effects of 3-Month Contraceptive Injection at BPM L Banjaranyar Village
Authors: M Safira Rizky , Margiana Wulan
Published: January 2022

The increasing world population will cause many problems in various fields, especially in the social and economic fields. Thus, the government has taken an action by launching a family planning program to control the rate of population growth. One of the most popular family planning programs is the 3-month injection KB with side effects. This study aimed to determine the effect of the provision of communication, information, and education regarding the side effects of using a 3-month injection of KB on the level of knowledge of family planning acceptors about the side effects of using KB in BPM L in Banjaranyar village. This was comparative research with a quantitative approach. The number of samples was 15 respondents in both the intervention group and the control group. In addition, the data were collected using a questionnaire and were analyzed using the Fisher test. The result showed that there were 15 respondents (100%) in the intervention group with good predicate, while the level of knowledge in the control group with good predicate was 8 respondents (53%) and 7 respondents (40%) not good predicate. Then the P-value obtained from the Fisher test was 0.006, so the p-value was 0.05. There was an effect of the provision of communication, information, and knowledge regarding the side effects of using 3-month injectable contraceptives on the level of knowledge of family planning acceptors in BPM midwives in Banjaranyar village.
A Report of Post-Concussion Syndrome in Post-Moderate Traumatic Brain Injury Patients
Authors: Maulinda Yuanita Eka , Endiyono Endiyono
Published: January 2022

Traumatic brain injury is the most common injury, especially in motorcycle riders who do not wear helmets or those who wear unsafe helmets. This injury can be fatal and result in death, but it can also be healed without any sequelae or with varying sequelae. The type of sequelae that commonly occurs after a traumatic brain injury is Post-Concussion Syndrome. Moreover, it has some symptoms such as headaches, impaired concentration, tiredness, anxiousness, dementia, and impaired cognitive function. Based on its onset, Post-Concussion Syndrome is classified into 3: acute (the symptoms appear less than one month after injury), subacute (the symptoms appear from 1 to 12 months), and chronic (the symptoms appear more than a year). The purpose of this research is to provide an overview of symptoms in cases of Post Concussion. Syndrome that occurs after 6 months after moderate head injury.The design of this study used a case report method in order to report cases in detail through interviews and direct observation on respondents. The results of Rivermead, Galveston Orientation and Amnesia Tests conducted 6 months after moderate traumatic brain injury, indicated that respondents experienced Post-Concussion Syndrome and Retrograde Amnesia. The conclusion of Post-Concussion Syndrome experienced by the respondents was subacute with several symptoms such as headache, dementia, impaired concentration, anxiousness, and memory loss of before injury.
Actualization of the role of Vitamin B12 in physiology and endocrine disorders
Authors: Shulpekova N. V. , Belaya Zh. E. , Galstyan G. R.
Published: January 2022

Vitamin B12 (cobalamin) is a collective name for a group of water-soluble cobalt-containing biologically active compounds belonging to corrinoids. Vitamin B12 is essential for hematopoiesis, the formation of epithelial tissue; as a coenzyme, it is involved in the metabolism of fatty acids, carbohydrates, nucleic acids. Cobalamin defi ciency is associated with the development of anemia, polyneuropathy, and decreased cognitive function. Due to the nonspecifi city of symptoms and the possible development of severe and potentially irreversible complications, it is important to conduct timely screening among patients from risk groups. Among endocrine disorders, vitamin B12 defi ciency is found in patients with diabetes mellitus, obesity and autoimmune thyroid disease mostly. In particular, metformin may cause a decrease in vitamin B12 levels and polyneuropathy, which is diffi cult to diff erentiate from diabetic polyneuropathy. In patients with autoimmune thyroid lesions, other autoimmune diseases are often observed, atrophic gastritis and pernicious anemia notably. Vitamin B12 malabsorption can lead to defi ciency even when consumed adequately, which possibly explains the relatively high prevalence of B12 defi ciency in patients with autoimmune thyroid disease. This literature review summarizes recent advances on the role of vitamin B12 metabolism, potential risk groups for vitamin B12 defi ciency among common endocrine diseases, and the benefi t for its replacement with high-dose oral forms, cyanocobalamin 1 mg in particular
PENGARUH PEMBELAJARAN ONLINE DI TENGAH PANDEMI COVID-19 TERHADAP HASIL BELAJAR TEMA 9 KELAS V SD NEGERI CEMPAKA 01 TEGAL
Authors: Muttaqin Muh , Listyarini Ikha , Agustini Ferina
Published: January 2022

This study was conducted to determine the effect of online learning in the Covid-19 pandemic on learning outcomes in the 9th-grade theme of SDN Cempaka 01 Tegal. Type of quantitative research. The population in the study were all fifth-grade students of SD N Cempaka 01 Tegal. The research method used is a survey method. Singarimbun (2011: 3) explains that research with this survey method is a study that takes a sample from a population and uses a questionnaire as the main data collection tool. The questionnaire is a data collection tool that is done by giving a set of questions or written statements to the respondent to answer. The results showed that there was a positive influence on student learning outcomes. This is evidenced by the results of the analysis showed that the calculation of the product-moment correlation (rxy) between online learning (X) and learning outcomes (Y) obtained a correlation coefficient of 0.570. The coefficient r table with a significance level of 5% and N = 18 is 0.468. These results indicate that rcount is greater than rtable so that Ho is accepted. It can be concluded that there is a positive and significant influence between online learning in the Covid 19 Pandemic and the learning outcomes of Class V students at SDN Cempaka 01 Tegal.
PENANAMAN NILAI-NILAI KARAKTER PADA PEMBELAJARAN TEMATIK BERMUATAN IPS SECARA DARING SISWA KELAS IV DI SDN KEPEK II SAPTOSARI GUNUNGKIDUL
Authors: Erlinda Erlinda , Zulfiati Heri Maria
Published: January 2022

This study aims to describe: (1) The importance of instilling character values in bold learning, (2) instilling character values in thematic learning with social studies in a bold manner, (3) regulated constraints & solutions in instilling values characters in thematic learning with social studies in a bold manner. The research was conducted at SDN Kepek II Saptosari Gunungkidul for grade IV students (15 students). The research was conducted in January 2021. The data sources were the principal, fourth-grade teachers, parents & students. The data technique uses observation, interview, & documentation techniques. The research instruments were observation, interview, & documentation. Test the validity of the data using input, improve persistence, triangulate (source, technique, & time), & use reference materials. The data analysis technique uses Miles & Huberman analysis which consists of data collection, data reduction, data presentation, and data retrieval. The results showed that (1) instilling character values is very important so that students have good attitudes & behavior. (2) Instilling character values is done in learning activities & outside learning; character values that have been successfully instilled are religion, the enthusiasm of reading, discipline, responsibility, honesty, environmental care attitude, and social care attitude. (3) Obstacles that inform & the solution is that if the child does not have a smartphone, the children can take & collect assignments at school, the information is forwarded to other students' parents, the teacher visits the student's house, the teacher gives time to arrange assignments until 21.00 WIB, the teacher uses various learning media to help the students understand the material, teacher supervision is limited so that parents include their children in tutoring & TPA activities to support the instilling of character values in children.
Es ist kompliziert
Authors: El-Djouini Senzena
Published: January 2022

Aus einer autobiographischen Perspektive reflektiert der Beitrag die Bedeutung von Herkunft, Migrationshintergrund und Bildung für die Entwicklung einer professionellen, supervisorischen Identität. Dabei wird auch die Relevanz von Migrationserfahrung für die Platzierung am Markt in den Blick genommen.
Vielfältige Verantwortungen
Authors: Steinweg Nina
Published: January 2022

Dieser Beitrag widmet sich den Herausforderungen von Hochschulen als diskriminierungssensiblen Organisationen im Spannungsfeld von New Public Management, Wettbewerb um die »besten Köpfe«, Unterfinanzierung und der Verantwortung für ein gerechtes und diskriminierungsfreies Bildungssystem. Er wirft einen Blick auf die Strukturen von Diversity Management und Antidiskriminierungspolitik im Lichte der rechtlichen Rahmenbedingungen.
Diversität in Supervisionen
Authors: Stritzke Nadyne
Published: January 2022

Der Beitrag argumentiert, dass Diversität in Supervisionen eine Realität ist, die gelegentlich als Zumutung erlebt werden kann. Das besondere Potenzial von psychodynamischer Supervision besteht darin, die Zumutung als eine legitime Emotion anzuerkennen und ernst zu nehmen. So kann Supervision in den gesellschaftlichen Debatten einen konstruktiven Beitrag leisten, den Spaltungstendenzen zwischen Akzeptanz und Ablehnung von Vielfalt entgegenzuwirken.
Diversität in der Supervision
Authors: Gruber Doris
Published: January 2022

Der Artikel diskutiert anhand von zwei Fallbeispielen, wie die Themen Vielfalt und Diskriminierung in Arbeitsfelder und Supervision eindringen. Ausgehend von Kristevas Konzept des »Fremden« [Étranger] sowie Davids’ Modell des »inneren Rassismus« wird der Umgang mit kultureller Vielfalt am Beispiel einer Teamsupervision ausgeführt. Im Fokus stehen der innere und äußere Umgang mit »dem Fremden« sowie die Entwicklung von Abwehr als Schutz. Im zweiten Fallbeispiel greifen das Thema Gender und sexuelle Orientierung bei einer Mobbing-Dynamik ineinander. Das Modell des »inneren Rassismus« zeigt sich als generelle Abwehrstrategie übertragbar und fruchtbar für die Hypothesenbildung bezüglich weiterer Diskriminierungsfelder.
Divertículo duodenal intraluminal como causa de obstrucción duodenal
Authors: Pérez-Quintero Rocio , Alba-Valmorisco Marcos , Candón-Vázquez Juan , González-Serna Daniel Bejarano , Balongo-García Rafael
Published: January 2022

Introducción. El divertículo duodenal intraluminal, también conocido como windsock diverticulum, es una causa rara de dolor abdominal intermitente y plenitud postpandrial, que puede complicarse con obstrucción, sangrado, pancreatitis o colangitis. Suele cursar de forma asintomática y ante la aparición de síntomas el tratamiento de elección es quirúrgico.
Caso clínico. Presentamos el caso de una mujer de 24 años, sin antecedentes de interés, que es estudiada por dolor abdominal y plenitud postpandrial, que resulta finalmente en una obstrucción intestinal alta. Tras estudio exhaustivo y necesidad de una cirugía previa, es diagnosticada de un divertículo duodenal intraluminal.
Conclusión. La paciente se trató mediante cirugía con resolución exitosa del cuadro de obstrucción intestinal.
Protocolo para el manejo de placenta percreta con cesárea, embolización uterina e histerectomía diferida
Authors: Jiménez-Jiménez Cesar Eduardo , Niño-González Jorge Ernesto , Meneses-Parra Angy Lorena
Published: January 2022

Introducción. El objetivo de este artículo fue dar a conocer el protocolo institucional del manejo de la placenta percreta como un procedimiento varias horas después de la cesárea, con embolización de arterias placentarias de forma selectivas, previo a la práctica de la histerectomía, y presentar los resultados.
Métodos. Estudio de serie de casos, donde se evaluaron las pacientes con placenta percreta, manejadas durante un año en un hospital de cuarto nivel de complejidad en la ciudad de Bogotá, D.C., Colombia. Se efectuó cesárea fúndica y se dejó la placenta in situ, 48 a 72 horas después se realizó embolización ultra selectiva y luego de 2 a 3 días se procedió a practicar la histerectomía vía abdominal.
Resultados. Se evaluaron 5 pacientes, con paridad de 3,8 embarazos promedio, con diagnóstico de placenta percreta. El tiempo promedio de espera entre la embolización y la histerectomía fue de 1,6 días. No se presentaron complicaciones asociadas a la embolización, ni morbimortalidad materno fetal. Los volúmenes de sangrado en promedio durante la histerectomía de cada paciente fueron de 1160 ml.
Conclusión. Existen datos limitados sobre el tratamiento óptimo del acretismo placentario. La sospecha diagnóstica permite planificar de forma favorable el manejo intraparto y, es por ello, que el surgimiento de nuevas técnicas, como la embolización de arterias placentarias, constituyen alternativas para un manejo más seguro de las pacientes.
Reconstrucción de estenosis traqueal benigna: experiencia de un hospital de alta complejidad en Colombia
Authors: Alvarado-Sarzosa Fernando , Peláez Mauricio , Russi Hernando , Bayona Juan Gabriel , Cendales Angélica , Rosselli Diego
Published: January 2022

Introducción. La causa más común de estenosis laringotraqueal benigna es iatrogénica, secundaria a intubación orotraqueal. El manejo quirúrgico sigue siendo la alternativa que ha mostrado mejores resultados a largo plazo. El objetivo de este estudio fue analizar la experiencia en el manejo quirúrgico de la estenosis laringotraqueal durante 15 años en un hospital de alta complejidad en Colombia.
Métodos. En este estudio se revisaron las historias clínicas de todos los pacientes tratados con reconstrucción de estenosis traqueal benigna, entre los años 2005 y 2020. Para el análisis estadístico se usaron métodos de estadística descriptiva, con análisis de frecuencias y medidas de tendencia central o de dispersión.
Resultados. Se identificaron 38 pacientes con estenosis laringotraqueal, con un grado variable de estenosis. La nasofibrolaringoscopia fue bien tolerada y segura para determinar el grado y la longitud de la estenosis. El uso de tomografía sirvió para determinar la extensión y las características anatómicas. Los resultados del presente estudio son similares a los de la literatura en cuanto a complicaciones, mortalidad y falla de la anastomosis. Las complicaciones más frecuentemente reportadas son reestenosis, infección del sitio operatorio, lesión nerviosa y fístula, que en general se presentan en un tercio de los pacientes.
Conclusiones. La experiencia de manejo quirúrgico de estenosis laringotraqueal en este hospital permite concluir que la reconstrucción traqueal es una opción segura en nuestro medio. Las tasas de éxito y de falla del tratamiento son equiparables a las reportadas en la literatura.
Cuerpo extraño como causa de apendicitis aguda complicada
Authors: Vélez-Bernal Jorge Luis , González-Díaz Cristina Estefanía , Agudelo Jiménez Leidy Dayana
Published: January 2022

La apendicitis aguda es una de las patologías más comunes en el ámbito hospitalario. Las formas complicadas pueden ser causadas por objetos puntigudos, afilados, delgados o alargados, ingeridos de forma accidental, y representan una causa inusual con una prevalencia del 0,0005 %.
Theoretical Perspectives of the Effect of Immunotherapy on the Quality of Life of Cancer Patients
Authors: Johncy Swapna
Published: January 2022

Immunotherapy is a type of treatment that improves an individual’s ability to detect and attack cancerous tissues. The main objective of adopting immunotherapy in cancer treatment is to improve the patient’s quality of life (QoL). To address the problems faced by cancer patients post immunotherapy, it is critical to conduct an extensive review to understand the factors impacting the QoL of immunotherapy patients. Quality of life is a concept very relevant to the discipline of nursing. With instrument development and population description, oncology nurses have improved the quality of life in cancer patients. The theoretical proposition of behavior change may be the best fit for understanding the difference in cancer patients’ quality of life after immunotherapy, but it has limited scope of application considering its deficit in theoretical components. In cooperation with doctors and other health professionals, nurses need to develop a conceptual framework of QoL specific to immunotherapy to measure patient‐reported outcomes in this cohort of patients. Keywords: immunotherapy, cancer, quality of life, cancer theory, cancer patient
David and Goliaths
Authors: Ivanov Andrey V.
Published: January 2022

This article explores the content of wartime sermons in eighteenth-century Russia, delivered by the Orthodox bishops during the pivotal military conflicts of early imperial period. Apart from communicating war aims and current events to the laity, these sermons also presented an image of the enemy to the masses. This imagery manifested bishops’ support for the Petrine and Catherinian cultural opening to the West, on the one hand, while promoting a myth of an existential antagonism against the Ottoman South, on the other. Unlike their seventeenth-century predecessors, eighteenth-century sermons avoided the stereotypes of heterodoxy or heresy when describing Russia’s Western enemies, preferring instead the language of just or unjust wars, protection of European neighbors or the metaphor of David facing titanic Goliaths. The non-sectarian imagery, however, did not extend to Islam. Sermons of the Russo-Ottoman wars presented the conflict as a purely religious and Russia’s involvement as a holy war.
Family Law Enforcement Problems and Islamic Heritage in Thailand
Authors: Puteh Mada O , Jehwae Phaosan
Published: January 2022

The Islamic Law on Family and Inheritance of 1946 was enforced only in the four southern provinces of Thailand consisting of Pattani, Narathiwat, Yala and Setun Provinces. Islamic law applies only to the plaintiff, defendant or applicant who submits a request must be Muslim. The problem of law enforcement consists of the lack of clarity in the terms of membership of the Provincial Islamic Committee in the 1997 Law on the Administration of Islamic Organizations. The problem of setting the condition that requires Datok Qadi to be alone in deciding matters of Islamic law. Datok Qadi's decision is absolute and cannot be appealed. The problem of limiting the enforcement of Islamic law can only be enforced in court. Solving the problem in avoiding the legal inconsistency can be done by expanding the enforcement of family and inheritance law outside the court. In addition, there is also a need for legal reform, both the Islamic Law on Family and Inheritance of 1946 and the 1997 Law on Administration of Islamic Organizations which are clearer.

 
Nazhariyah Noam Chomsky fii An-Numu Al-Lughawi wa In’ikasatuha ‘ala Ta’lim Al-Lughah Al-Arabiyah
Authors: Ningsih Anita Andriya , Munir Muhammad Mubasysyir , Mustapa Mustapa
Published: January 2022

Chomsky argues that the language is too complicated to learn through passages, such as studying city rosters around the world. Since the early 1970s, theoretical disciplines and teaching methodologies have continuously sought to realize their symbiotic relationships. Teaching language within the framework of Chomsky's theory should give students an appropriate linguistic description with due regard to the student's intellectual level. Language is not only a device for capturing information from what it has learned, but in fact it returns to the student's mental and cognitive ability to complete the process.

يرى تشومسكي بأن اللغة معقدة للغاية بحيث لا يمكن تعلمها من خلال المقاطع ، مثل دراسة قوائم المدن حول العالم. منذ أوائل السبعينيات ، سعت التخصصات النظرية ومنهجيات التدريس باستمرار إلى إدراك علاقاتها التكافلية. يجب أن تعطي لغة التدريس في إطار نظرية تشومسكي للطلاب وصفًا لغويًا مناسبًا مع إيلاء الاعتبار الواجب للمستوى الفكري للطالب. اللغة ليست فقط أداة لالتقاط المعلومات مما تعلموه ، ولكنها في الواقع تعود إلى قدرة الطالب العقلية والمعرفية لإكمال العملية.