bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGEMBANGAN E-LKPD BERDASARKAN TEORI APOS DENGAN PENDEKATAN ETNOMATEMATIKA UNTUK MENINGKATKAN PEMAHAMAN KONSEP SISWA SMA
Authors: Mushlihah Rohmah  , Annisa Nur Azizah  , Wening Tyas  , Lisa Pratama
Published: July 2024

Penelitian ini bermula dari fakta yang ada di lokasi penelitian dan berdasarkan hasil observasi dan wawancara bahwa siswa belum mampu menyelesaikan permasalahan yang disajikan karena kemampuan pemahaman konsep siswa masih rendah. Penelitian ini bertujuan mengembangkan E-LKPD berbasis teori APOS dengan pendekatan etnomatematika yang mampu meningkatkan pemahaman konsep siswa. Jenis penelitian yang digunakan adalah penelitian dan pengembangan. Prosedur pengembangan E-LKPD menggunakan model 4-D yang tediri dari 4 tahapan: pendefinisian, perancangan, pengembangan, penyebaran. Hasil penelitian menunjukkan bahwa E-LKPD berbasis teori APOS dengan pendekatan etnomatematika untuk meningkatkan kemampuan pemahaman konsep siswa memiliki kriteria valid dari ahli materi dan ahli media serta kriteria praktis dari angket respon siswa. Berdasarkan Uji Hipotesis, E-LKPD berbasis teori APOS dengan pendekatan etnomatematika juga efektif meningkatkan kemampuan pemahaman konsep siswa.
Kata kunci: Teori APOS, etnomatematika, pemahaman konsep
Editorial: Memory from Below
Authors: Castillo Gómez Antonio , Martínez Miguel
Published: July 2024

The editorial provides an overview of this issue of the Journal of Early Modern Studies. First it lays out the research questions that were at the origin of the project. Then it sketches out its conceptual and historiographical armature, pointing to some classical and recent arguments about memory, the history of literacy, and popular writing. Finally, this essay surveys the structure of the special issue and summarizes the object and argument of each one of the fifteen contributions.
DESENVOLVIMENTO DE COMPETÊNCIAS EM SAÚDE PÚBLICA: PERCEPÇÃO DE PROFISSIONAIS-GESTORES SOBRE EFEITOS DE CURSO NA MODALIDADE À DISTÂNCIA
Authors: Cunha Sade Priscila Meyenberg
Published: July 2024

Introdução: a pandemia COVID-19 trouxe desafios às instâncias responsáveis pela qualificação dos profissionais de saúde no mundo todo, que necessitaram se adaptar para oferta de cursos na modalidade à distância, frente às implicações impostas, como o distanciamento social. Entretanto, a despeito desses cursos, ainda persistem lacunas na produção de conhecimentos dos seus efeitos. Objetivo: analisar a percepção de profissionais-gestores sobre os efeitos de um curso na modalidade à distância, implementado para desenvolvimento de competências em saúde pública em tempos de pandemia COVID-19. Metodologia: pesquisa qualitativa realizada a partir de dados coletados do ambiente virtual do curso que, dentre outras informações, possuía respostas de uma pergunta realizada para os profissionais-gestores um mês após a sua conclusão: quais tarefas você executa habitualmente que sofreram algum tipo de modificação em consequência de sua participação no curso? A análise dos dados ocorreu por Classificação Hierárquica Descendente com auxílio do software IRAMUTEQ®, a partir de segmentos simples de texto (SST). Os SST foram classificados em função dos respectivos vocabulários de maior frequência e das palavras com associação significativa (p<0,001). Por fim, o software produziu um dendrograma com a ilustração do esquema hierárquico de classes. . Resultados: foram processadas 256 respostas com aproveitamento de 76,3% dos SST, que resultaram em um dendrograma de quatro classes, sendo possível constatar modificações na/o: (1) Execução de tarefas do cotidiano laboral; (2) Ampliação do conhecimento acerca do trabalho no Sistema Único de Saúde; (3) Articulação entre áreas para desenvolvimento das ações em Saúde Pública; (4) Apoio e orientações de ações de vigilância em saúde junto aos municípios. Considerações Finais: o uso do software IRAMUTEQ® facilitou o processamento e a análise de grande número de dados qualitativos. Destarte, foram obtidos achados que apontaram mudanças significativas na prática profissional dos gestores e, consequentemente, efeito positivo no desenvolvimento de competências.
INTERVENSI APOTEKER MENUNJANG PERBAIKAN PERILAKU BEROBAT PENDERITA HIPERTENSI
Authors: Ariyani Herda , Akrom  , Alfian Riza
Published: July 2024

Based on Riskesdas data (2018), the prevalence of hypertension in South Kalimantan was 10.81% or higher in 2020 compared to the national average of 8.8%. High blood pressure can increase the risk of cardiovascular disease when combined with risk factors like obesity, bad eating habits, smoking, and a sedentary lifestyle. A strategy that incorporates the pharmacist's reminders and motivation through the use of short messaging services (SMS) and modified brief counseling is required to help patients behave better when taking drugs in order to achieve therapeutic success. The purpose of the study is to determine how both interventions affected the drug use of street hypertensive patients at X Hospital Banjarmasin. With a Randomized Pre-test – Post-test Control Group Design, the study project is an experimental quota. The prospective data collection was done on road nursing patients. 34 patients (or 50% of the total) were assigned to the treatment group, and 34 individuals (or 50% of the total) were assigned to the control group, after meeting the inclusion criteria of 68 hypertensive patients. Drug-related behavior questionnaires and interviews were used to gather data. Pharmacists who administered both of these programs found that the treatment group's drug behavior score increased significantly (p<0,05).
ANALISIS KADAR TIMBAL (Pb) PADA BEDAK PADAT YANG BEREDAR DI BANJARMASIN MENGGUNAKAN METODE SPEKTROFOTOMETRI SERAPAN ATOM
Authors: Huzaeroh Anifatu , Lestari Yulianita Pratiwi Indah , Hayati Mardia
Published: July 2024

Bedak padat merupakan salah satu jenis kosmetik yang umum digunakan dan keamanannya harus dijamin agar terbebas dari cemaran.  kosmetik adalah timbal (Pb). Tujuan dari penelitian ini adalah mengetahui keberadaan cemaran timbal (Pb) pada bedak padat yang beredar di Banjarmasin menggunakan metode spektrofotometri serapan atom. Metode yang digunakan meliputi uji kualitatif dengan pereaksi NaOH 1 M dan uji kuantitatif yang telah divalidasi Spektrofotometri Serapan Atom. Hasil dari uji kualitatif menunjukkan kelima sampel reaktif setelah direaksikan dengan NaOH 1 M dan menghasilkan endapan bewarna putih. Hasil uji validasi metode menunjukkan nilai R=0,9996, LOD=0,019994243 ppm dan LOQ=0,06664748 ppm.  Dari uji kualitatif kelima sampel terindikasi mengandung adanya timbal, oleh karena itu dilanjutkan dengan uji kuantitatif. Hasil uji kuantitatif menunjukkan kadar timbal dalam sampel dengan kode A, B, C, D, dan E sebesar 3,346 mg/kg; 4.894 mg/kg; 3.920 mg/kg; 3.284 mg/kg; dan 1,829 mg/kg. Dapat disimpulkan meskipun masih ada bedak padat yang mengandung timbal (Pb), tetapi masih di bawah batas aman cemaran timbal yaitu <20 mg/kg.
PEMANFAATAN TRIGGER TOOL DALAM MONITORING DAN DETEKSI ADVERSE DRUG REACTION PADA PASIEN RAWAT INAP GERIATRI DI RSI PKU MUHAMMADIYAH PEKAJANGAN PEKALONGAN
Authors: Prasetya Henry Budiman , Lolita
Published: July 2024

Pentingnya pemantauan dan deteksi adverse drug reaction (ADR) pada pasien rawat inap geriatri tidak bisa diabaikan. Pasien geriatri rentan terhadap efek samping obat karena perubahan fisiologis terkait penuaan, peningkatan jumlah obat yang dikonsumsi, dan peningkatan sensitivitas efek obat. Tujuan penelitian untuk mendeteksi ADR dengan menggunakan trigger tools pada pasien rawat inap geriatri di RSI PKU Muhammadiyah Pekajangan Pekalongan dan mengetahui hubungan karakteristik pasien dengan kejadian ADR. Metode penelitian observasional dengan desain kohort retrospektif. Sampel seluruh pasien geriatri usia ≥ 60 tahun dan dirawat inap lebih dari 48 jam periode Juli - September 2023. Instrumen penelitian menggunakan trigger tools dari pedoman geriatri Belanda. Analisis Data dengan software Microsoft Excel 2016 dan SPSS 21.0.  Hasil penelitian terdeteksi 393 kombinasi trigger drug pada 34,1% (n = 197/577) pasien. Trigger insufisiensi ginjal, hiperglikemi, hiponatremia, hipotensi/pusing, dan diare/muntah mencakup 86,5% (n = 340/393). Positive predictive value (PPV) keseluruhan dari triggers 49,4%, mayoritas ADR disebabkan angiotensin receptor blocker (ARB), diuretik loop, NSAID, diuretik hemat kalium, dan kortikosteroid, yang mencakup 69% dari semua obat yang menyebabkan ADR. Analisis hubungan  menunjukkan faktor usia memberikan pengaruh terjadinya ADR. Kesimpulan menunjukkan nilai trigger drug sebagai tools untuk mendeteksi ADR pada pasien geriatri rawat inap di RSI PKU Muhammadiyah Pekajangan Pekalongan.
Obstacles and Challenges Affecting Quality Indicators in a Complex Tertiary Emergency Center
Authors: Jaber Mohammad J. , Bindahmsh Alanoud A. , Abu Dawwas Mohammad A. , du Preez Susanna E. , Alshodukhi Abeer M. , Alateeq Ismail S. , Binti Abd Rahman Norah S.
Published: July 2024

Introduction

Hospital performance is significantly affected by external factors (political and economic) rather than internal factors (effectiveness and efficiency). Emergency department (ED) overcrowding is a significant issue for emergency care services globally, characterized by a rising number of visits and persistent unsolved issues, resulting in increased challenges faced by ED staff and decreased patient satisfaction. This study aimed to explore the obstacles and challenges that cause variation in ED quality indicators (QIs) based on five domains: infrastructure, population, workflow, workforce, and administration.

Methods

A tertiary emergency center in Saudi Arabia administered a questionnaire with standardized measures to 180 nurses, using a cross-sectional descriptive design.

Results

Most nurses (75.5%) believed that crowded waiting rooms in the ED were the most influential factor affecting QIs. Many other challenges were identified, including bed capacity, triage area/workflow, increased volume during peak periods, demand for nonemergency visits, staff and shortages. Significant differences in nurses’ responses were found on the basis of education level (for infrastructure only, p = 0.004), specialty (for nursing administration only, p = 0.052), and ED experience (for all variables, p = 0.008–0.039).

Conclusion

The analysis uncovered various critical aspects of infrastructure, workflow, population, workforce, and nursing administration that have a major effect on patient flow in the ED.Comprehending these aspects will greatly affect the quality measures of ED performance and assist policymakers in formulating strategic plans to enhance ED performance. Therefore, successful implementation and optimization of ED resources depend greatly on considering the right decision variables and resource restrictions.
Correlation Between the Severity Of Chronic Rhinosinusitis and The Degree of Osteitis Based On Computerized Tomography Evaluation
Authors: Israchmadi Ardiga , Ningrum Farah Hendara , Baskoro Nurdopo , Dewi Anna Mailasari Kusuma
Published: July 2024

BACKGROUND: The incidence of chronic rhinosinusitis (CRS) is increasing every year, characterized by inflammation of the nasal and paranasal sinuses mucoperiosteum for more than 12 weeks. The inflammatory process of CRS sometimes spreads to the surrounding bone tissue resulting in osteitis. Computerized tomography scan (CT scan) can assess the degree of mucosal inflammation using the Lund-Mackay score (LMS) while the degree of bone thickening and remodelling are assessed with Global osteitis score (GOS) and Kennedy osteitis score (KOS).
AIMS: To evaluate the correlation between CRS severity assessment using LMS and osteitis severity assessment using GOS and KOS
METHODS: A retrospective analysis using a cross-sectional design was conducted that included 63 CT scans of the paranasal sinus of CRS patients. The spearman rank test was used to analyze data.
RESULTS: Assessment using LMS showed 44% patients were classified as severe, while 29% and 27% patients were classified as moderate and mild respectively. Global osteitis score showed 2% patients were categorized as severe, while 22% and 46% patients were categorized as moderate and mild respectively, and 30% patients were not significant. Based on KOS assessment, it was found that 3% patients were classified as severe, while 38% and 59% patients were classified as moderate mild respectively. There was a significant correlation between CRS severity using LMS and GOS (p 0.000) with rho= 0.951. There was a significant correlation between CRS severity using LMS and KOS (p 0.000) with rho value= 0.452.
CONCLUSION: This study shows a significant correlation between CRS severity assessment using LMS and bone thickening and remodelling assessment using GOS and KOS. In comparison with KOS, GOS has stronger relationship with LMS.
Effect of Cold Temperature on the Severity of Allergic Rhinitis Based on Visual Analog Scale (VAS) Score Among Medical Students of Malikussaleh University
Authors: Zuhra Farianti , Rahayu Mulyati Sri , Putri Baluqia Iskandar
Published: July 2024

BACKGROUND: Allergic rhinitis is a common condition caused by inflammation of the nasal mucosa after exposure to allergens and is mediated by Immunoglobulin E (IgE). Cold temperatures can aggravate the symptoms of allergic rhinitis. Allergic rhinitis is not fatal, but it can cause a decrease in the patient's quality of life if the symptoms are severe. The severity of allergic rhinitis symptoms is difficult to measure as it should match patient's perception, so VAS is a quantitative measurement tool used. Although VAS is a simple and easy-to-use tool, its use as self-monitoring for AR patients is still infrequent to minimize symptom exacerbations and maintain control of allergic rhinitis.
AIMS: This study aims to examine the effect of cold temperature on the severity of allergic rhinitis based on VAS score.
METHOD: This research is an experimental with a one-group pretest-posttest study. The study samples involved 75 students suffering from allergic rhinitis assessed with the Score for Allergic Rhinitis (SFAR) questionnaire assessment from the class of 2020, 2021, and 2022. Subjects’ pain level was measured before and after the intervention. The intervention was in the form of cold temperature exposure for 15 minutes in a room with a temperature of 18℃. Data were analyzed using the Wilcoxon test.
RESULT:  The results showed that the mean VAS score before the intervention was 0 while after the intervention was 38.61 ± 24.07. This shows that the mean VAS score after the intervention is higher than the mean VAS score before the intervention (p-value = 0.00 <0.05).
CONCLUSION: The results of this study indicate that the effect of cold temperature can increase the severity of allergic rhinitis.
Acute Inferior ST-elevation Myocardial Infarction Arising from Wrap-Around Left Anterior Descending Artery Occlusion
Authors: Nugraha Daniel , Pesireron David Jonathan , Dhani Muhamad Sofan , Yudha Ardi , Safir Safir
Published: July 2024

BACKGROUND: Acute myocardial infarction (AMI) remains a leading cause to global morbidity and mortality. Inferior MI predominantly stems from the right coronary artery (RCA) in more than 80% of instances, the left circumflex coronary artery (LCx) in fewer than 20% of cases, and infrequently from the left anterior descending artery (LAD)
AIMS: This case report aims to highlight a rare occurrence of LAD occlusion initially manifested as inferior MI.
CASE: A 56-year-old male presented with typical chest pain lasting for 6 hours. Vital signs were within normal range. Initial electrocardiogram (ECG) revealed ST-segment elevation in inferior leads (II, III, aVF). Laboratory tests indicated elevated troponin levels (>25ng/mL). Coronary angiography identified the culprit lesion as the LAD, which wrapped around the apex.
DISCUSSION: While ECG alterations are valuable in identifying thrombosed vessels during AMI, the presence of simultaneous ST elevation in both inferior and anterior leads can hinder clinicians' ability to determine the specific artery affected by the infarction. Our case, depicting a scenario where both the right and left coronary arteries are co-dominant, showed complete occlusion at the mid-distal wrap-around LAD, resulting in ST-elevation observed in both inferior and anterior leads.
CONCLUSION: The existence of inferior ST-segment elevation alongside alterations in anterior leads could imply occlusion of the wrapped LAD.
PERFORMANCE AND MEAT QUALITY OF BROILER CHICKEN FED GRADED LEVELS OF BLACK COFFEE SEED (COFFEE ARABICA) POWDER SUPPLEMENTED DIET
Authors: Awodoyin Olayemi , Obafemi Ayodele, Ifeoluwa , Agamugaga Iruoghene, Blessing
Published: July 2024

Oxidative degradation is a deleterious condition that affects quality of meat, thereby poses a threat to poultry industry. However, this can be mitigated through feeding with antioxidants, therefore the need for inclusion of high antioxidant compound, such as coffee, in poultry diet. One-day old Ross 308 chicks (n = 200; r = 5) were randomly allotted to four diets containing black coffee seed powder (BCSP): 0.0 g/kg; 1.25 g/kg; 2.50 g/kg and 3.75 g/kg. Birds were fed ad libitum with free access to water for 6 weeks. Total weight gain (TWG) (g/b), total feed intake (TFI) (g), feed conversion ratio (FCR), haematology, oxidative markers, gut microbiology (x105cfu/mL) of birds, sensory characteristics (9-point hedonic scale) and total volatile nitrogen base (TVB-N) (mg/100 g) of broiler meats were assessed. Data were analyzed using ANOVA at P = 0.05. No significant differences in TWG (1873.12 − 1927.58) and FCR (1.55 − 1.71) were observed. However, TFI at 3.75 g/kg of BCSP (3216) was higher (P < 0.05) than at 0 g/kg (3090), 1.25 g/kg 2967 and 2.50 g/kg of BCSP (3072) in the bird diet. Haemoglobin (12.60) at 1.25 g/kg BCSP was higher (P < 0.05) than at 0 g/kg BCSP (10.83), but similar to the groups of 2.50 g/kg (10.97) and 3.75 g/kg (12.13) BCSP in the diet. Creatinine (0.97mg/dL) in the 1.25 g/kg BCSP group was higher (P < 0.05) than those in the 0 g/kg (0.68 mg/dL) and 3.75 g/kg (0.60 mg/dL) groups but similar to the 2.50 g/kg group (0.88 mg/dL). No significant differences in almost all the oxidative markers were recorded. Gut microbiology showed that heterophilic (11.60), Coliform (8.30) and E.coli (13.70) contents in the 0/kg BCSP group were higher (P < 0.05) than those in the 1.25 g/kg group (9.00, 5.58 and 4.48), the 2.50 g/kg group (3.55, 1.83 and 1.28) and 3.75 g/kg group (3.30, 0.53 and 0.25) for heterophilic, coliform and E. coli respectively. Lactobacillus in the 3.75 g/kg group (7.53) was higher (P < 0.05) than that in the 2.50 g/kg (5.63), the 1.25 g/kg (5.70) and 0 g/kg (1.58) groups. With the increase of BCSP inclusion, the TVB-N decreased; aroma and taste of BCSP meat were best and well accepted. Low pathogenic gut microorganisms and total volatile nitrogen base coupled with high sensory acceptability of meat confirm the antioxidant potential of black coffee in broiler chicken diet.
LEISHMANIOSE: REVISÃO DA INTEGRATIVA DA LITERATURA
Authors: Maria Coutinho Dias Grazielle , Fernandes da Silva Veras Esthe , Mariana Muniz de Araújo Marcela , Enderli do Nascimento Júlia , Morais Paixão Herika , Pereira Silva Adrielle , De Sousa da Silva Rosana , Nascimento de Melo Gabrielle , Nascimento de Melo Sarah , Rayle de Oliveira Nascimento Mirian , Alberto Pereira Rodrigues Sherdon , Marcos Santos Oliveira João , Souza Nascimento Santos Sayonara
Published: July 2024

O presente artigo tem como objetivo abordar sobre a Leishmaniose de forma ampla, com foco em sua epidemiologia e patologia. Metodologia: trata-se de uma revisão integrativa da literatura, com caráter exploratório e abordagem quanti-qualitativa embasada em publicações dos anos de 2019 a 2024 a respeito dos tipos da leishmaniose. A pesquisa foi realizada nas bases de dados da biblioteca virtual em saúde- PubMed, Scielo e PUBVET, devido serem fontes seguras para pesquisas. Concluímos que a Leishmaniose é uma zoonose que precisa ser mais abordada em espaços de saúde ou não, para que se tenha um entendimento considerável designado para controle e prevenção da mesma.
DESIGUALDADES DE GÊNERO NA ASSISTÊNCIA À SAÚDE DA MULHER: DESAFIOS E PERSPECTIVAS
Authors: Callegario Luísa do Valle , Nascimento Maria Eduarda Bezerra do , Gitai Alice Maria Plácido Caldas , Oliveira Bruna Stéfanny Mota de , Buosi Bárbara Proença , Costa Hyasmym da Silva , Diniz Lara de Ataíde , Brandao Monalise Lacerda Malta , Rosa Victor Hugo Júlio da , Lima Lorena Santos , Sousa Quemili de Cássia Dias de
Published: July 2024

Este artigo faz diversas distinções entre discursos de políticas de saúde pública para mulheres, especialmente mulheres indígenas, e discursos públicos que enfatizam aspectos das relações de gênero nas comunidades indígenas. Acreditamos que o desenvolvimento destas políticas públicas e a gestão dos serviços de saúde, por mais necessários que sejam, terão um efeito positivo nas relações de género no trabalho nas comunidades indígenas americanas. Por um lado, as relações de género entre os povos indígenas estão ligadas à esfera relacional e física. Enquanto isso, a prática de moldar políticas públicas por meio de práticas biomédicas e do tratamento dos corpos das mulheres torna-se uma ferramenta poderosa para moldar corpos e criar subjetividades, que permitem a construção de um movimento de mulheres indígenas.
FATORES DE RISCO PARA O DESENVOLVIMENTO DE DOENÇAS CARDIOVASCULARES EM IDOSOS: UMA REVISÃO INTEGRATIVA
Authors: Jana Daisy Honorato Borgo  , Thais Silva Fonseca  , Leticia Merchid Baltar  , Emerson Pellin  , Monique Albuquerque Amorim  , Auana Larissa Silva Ribeiro  , Déborah Bonatti de Medeiros Teixeira  , Luciana Cristina Mangini Martines  , Emilly Almeida de Mello  , Camile Brasil Soares Gondim
Published: July 2024

Objetivo: Descrever os fatores de risco para o desenvolvimento de doenças cardiovasculares na população idosa. Métodos: Trata-se de uma revisão integrativa de caráter descritivo e exploratório, efetuada em julho de 2024. A questão norteadora foi baseada de acordo com os domínios da estratégia PEO, resultando em: “Quais são os fatores de risco para o desenvolvimento de doenças cardiovasculares em idosos?” Diante disso, realizou-se uma busca na literatura nas bases de dados: LILACS, IBECS e MEDLINE via BVS. Logo, selecionaram-se como descritores os DeCS e os MeSH, interligados pelo operador booleano AND. Isto posto, oito artigos científicos foram incluídos na amostra final da pesquisa. Resultados e Discussão: De acordo com as evidências científicas, os fatores de risco mais comuns para o desenvolvimento de DCV são: Hipertensão arterial sistêmica, diabetes mellitus, dislipidemia, índice de massa corporal elevado, sedentarismo e tabagismo. Considerações finais: A utilização de informações acerca dos FR pode beneficiar na abordagem multidisciplinar à saúde dos idosos, especificamente ao prevenir complicações interligadas às doenças cardiovasculares, bem como informar o desenvolvimento de políticas públicas para um envelhecimento saudável.
TRATAMENTO PERIODONTAL EM PACIENTES DIABÉTICOS: REVISÃO DE LITERATURA
Authors: Gabriela Dias Gonçalves Paes  , Gabriella Rennisy de Sousa Silva  , Paloma Vitoria das Chagas Francisco  , Emylly Evyn Oliveira da Silva Matos Lima  , Tallita Silva de Assunção  , Mateus Henrique Hermes da Silva  , Yasmim Beatriz Marques da Silva Paz  , Nicolas de Andrade Luz  , Eduardo de Farias Barbosa
Published: July 2024

Introdução: A periodontite é uma doença multifatorial crônica causada pelo acúmulo de biofilme dental, possui seus períodos de exacerbação e remissão a depender da resposta do hospedeiro, fatores de risco como tabagismo, obesidade e idade avançada são conhecidos por contribuir para o seu desenvolvimento. O diabetes mellitus abrange um conjunto de distúrbios metabólicos caracterizados pela presença de níveis elevados de glicose no sangue, devido à deficiência na produção ou na ação da insulina. Embora os tipos 1 e 2 tenham uma base genética, fatores ambientais desempenham um papel importante em sua ocorrência. A presença de diabetes pode agravar o risco e a gravidade da doença periodontal, comprometendo a capacidade do corpo de combater a inflamação e aumentando a suscetibilidade a infecções. Objetivo: desse trabalho é realizar uma revisão de literatura sobre tratamento periodontal em pacientes diabéticos. A metodologia desta revisão integrativa foi baseada em buscas nas plataformas Biblioteca Virtual em Saúde (BVS), PubMED e Google acadêmico. Conclusão: O tratamento periodontal em pacientes diabéticos é de extremaimportância, pois quando feita de maneira correta traz ao paciente resultados benéficos.
Characterizations of Some New Classes of Four-Dimensional Matrices on the Double Series Spaces of First Order Cesaro Means
Authors: Bodur Okan , Gulec Canan Hazar
Published: July 2024

The main purpose in this study is to investigate some topological and algebraic properties of the absolutely double series spaces $\left\vert C_{1,1}\right\vert _{k}$ defined by combining the first order Cesaro means with the concept of absolute summability for $k\geq 1$. Beside this, we determine the $\alpha -$dual of the space $\left\vert C_{1,1}\right\vert _{1}$ and the $\beta \left( bp\right) -$ and $\gamma -$duals of the spaces $% \left\vert C_{1,1}\right\vert _{k}$ for $k\geq 1.$ Finally, we characterize some new four-dimensional matrix classes $\left( \left\vert C_{1,1}\right\vert _{k},\upsilon \right) ,$ $\left( \left\vert C_{1,1}\right\vert _{1},\upsilon \right) $, $\left( \left\vert C_{1,1}\right\vert _{1},\mathcal{L}_{k}\right) ,$ $\left( \left\vert C_{1,1}\right\vert _{k},\mathcal{L}_{u}\right) ,$ $\left( \mathcal{L} _{u},\left\vert C_{1,1}\right\vert _{k}\right) $ and $\left( \mathcal{L} _{k},\left\vert C_{1,1}\right\vert _{1}\right) $, where $\upsilon \in \left\{ \mathcal{M}_{u},\mathcal{C}_{bp}\right\} $ for $1\leq k<\infty $. Hence, some important results concerned on Ces\`{a}ro matrix summation methods have been extended to double sequences.
Dental cavity analysis, prediction, localization, and quantification using computer vision
Authors: Aqeel Muhammad , Norouzzadeh Payam , Maazallahi Abbas , Tutun Salih , Rouie Miab Golnesa , Al Dehailan Laila , Stoeckel David , Snir Eli , Rahmani Bahareh
Published: July 2024

Dental health assessment is a critical component of overall well-being, and advancements in computer vision and deep learning have opened new avenues for automating and enhancing this process. In this study, we present a comprehensive approach to dental cavity analysis, spanning localization, quantification, and visualization. Our methodology leveraged a diverse dataset of colored dental images that had been meticulously augmented and annotated. The You Only Look Once model was employed for precise dental cavity localization, providing bounding box predictions. Remarkably, these results were obtained based on images from standard device cameras. Subsequently, we introduced the use of the segment anything model segmentation model, known for its zero-shot generalization capabilities, to focus on the exact areas of dental cavities. This approach enhanced the granularity of our analysis, providing dental professionals with detailed visualizations for precise diagnosis. During the quantification phase, we extracted cavity areas from bounding box coordinates, enabling accurate measurement of cavity sizes. The model achieved a notable mean average precision of 0.732, an accuracy of 0.789, and a recall of 0.701. Moreover, the model converged quickly, with most metrics achieving near-optimal results after 100 iterations. This quantitative data augments traditional diagnosis methods, facilitating more informed treatment decisions.
Pictorial rendition of author’s observations on balloon valvuloplasty/angioplasty procedures: Aortic stenosis
Authors: Rao P. Syamasundar
Published: July 2024

Balloon aortic valvuloplasty (BAV) effectively decreases peak pressure gradients through the aortic valve both at the time of the procedure and during follow-up. This paper presents the author’s observations on the utility of BAV in treating congenital aortic valve stenosis (AVS). Previous work by the author noted intermediate-term restenosis and late-onset aortic insufficiency (AI). Factors contributing to restenosis include age under 3 years and post-balloon residual aortic valve gradients exceeding 30 mmHg. Repeat balloon valvuloplasty has been found to address restenosis effectively. However, the onset of AI at late follow-up is a significant disadvantage of BAV. Despite this, BAV is currently considered a beneficial treatment option for managing AVS in children, adolescents, and young adults. In contrast, seniors with calcific AVS do not experience relief from obstruction with BAV and are candidates for aortic valve replacement through transcatheter methodology, a procedure not reviewed in this paper. BAV provides relief of obstruction across the aortic valve and functions as an alternative to surgical intervention. Consequently, BAV is considered a preferred choice in addressing aortic stenosis in the pediatric patient.
A historical perspective on clonidine as an alpha-2A receptor agonist in the treatment of addictive behaviors: Focus on opioid dependence
Authors: Gold Mark S. , Blum Kenneth , Bowirrat Abdalla , Pinhasov Albert , Bagchi Debasis , A. Dennen Catherine , K. Thanos Panayotis , Hanna Colin , Lewandrowski Kai-Uwe , Sharafshah Alireza , Elman Igor , D. Badgaiyan Rajendra
Published: July 2024

Clonidine operates through agonism at the alpha-2A receptor, a specific subtype of the alpha-2-adrenergic receptor located predominantly in the prefrontal cortex. By inhibiting the release of norepinephrine, which is responsible for withdrawal symptoms, clonidine effectively addresses withdrawal-related conditions such as anxiety, hypertension, and tachycardia. The groundbreaking work by Gold et al. demonstrated clonidine’s ability to counteract the effects of locus coeruleus stimulation, reshaping the understanding of opioid withdrawal within the field. In the 1980s, the efficacy of clonidine in facilitating the transition to long-acting injectable naltrexone was confirmed for individuals motivated to overcome opioid use disorders (OUDs), including physicians and executives. Despite challenges with compliance, naltrexone offers sustained blockade of opioid receptors, reducing the risk of overdose, intoxication, and relapse in motivated patients in recovery. The development of clonidine and naltrexone as treatment modalities for OUDs, and potentially other addictions, including behavioral ones, underscores the potential for translating neurobiological advancements from preclinical models (bench) to clinical practice (bedside), ushering in innovative approaches to addiction treatment.
Enhancers and super-enhancers as master regulators in cancer
Authors: Sarvari Pouya , Sarvari Pourya , Ramirez-Diaz Ivonne , Rubio Karla
Published: July 2024

Gene expression regulation is one of the most fundamental cellular processes, enabling the activation of a gene to produce either the translatable protein-coding transcript (mRNA) or a functional non-coding RNA with gene regulatory functions, ultimately determining cell identity and function. Although gene expression regulation can occur at transcriptional, translational, and post-translational levels, transcription initiation is the first and the most important step in gene expression, facilitating the transfer of biological information from DNA to protein. Enhancers and super-enhancers are among the master regulators of tissue- and cell-specific transcription regulation involved in cell differentiation and tumor formation. Despite four decades passing since the first discovery of enhancers in eukaryotes and extensive efforts undertaken to identify enhancers on a genomic scale during the last decade, the discovery of enhancers still faces certain limitations and needs further investigation. The perturbation of enhancer function due to genetic or epigenetic changes is closely linked to a range of human disorders, including the development and progression of cancers. Thus, the detection of early cancer-related enhancer activity and the subsequent normalization of expression abnormalities using enhancer-targeting CRISPR epigenetic editing, as well as enhancer-targeting pharmaceuticals, are regarded as groundbreaking therapeutic tactics in preclinical stages.
Analisis Penawaran Produk Hortikultura Di Kabupaten Manggarai
Authors: Dep Aventus Purnama , Modesta Aswinda  , Piran Ronaldus Don , Ippi Viktorianus
Published: July 2024

Tanaman hortikultura dapat memberikan keuntungan bagi yang membudidayakan, yaitu menjadi sumber pendapatan dan memiliki keunggulan berupa nilai jual tinggi serta potensi serapan pasar di dalam negeri dan internasional yang terus meningkat. Penelitian dilaksanakan di Kabupaten Manggarai, Nusa Tenggara Timur. Tujuan penelitian adalah menganalisis rata-rata dan persentase rata-rata penawaran, rata-rata perubahan dan persentase perubahan jumlah penawaran, menentukan fungsi penawaran dan menganalisis elastisitas penawaran. Penelitian Penelitian ini dilaksanakan pada bulan November 2020 sampai September 2022 di Kabupaten Manggarai. Data yang digunakan dalam penelitian ini adalah data non-empirik, dalam hal ini digunakan data sekunder.  Teknik analisis data yang digunakan adalah analisis rata-rata, analisis persentase, analisis fungsi penawaran dan analisis elastisitas penawaran. Penawaran produk hortikultura (ton) di Kabupaten Manggarai Tahun 2015-2019, yaitu produk terung panjang sebanyak 362,57 ton, mentimun sebanyak 275,83 ton tomat sebanyak 1183,77 ton, Buncis sebanyak 525,57 ton dan bawang merah sebanyak 2024,8 ton. Rerata penawaran tahun 2015-2019 adalah produk terung panjang sebanyak 90,6425 ton, mentimun sebanyak 68,9575 ton, tomat sebanyak 295,9425 ton, buncis sebanyak 131,3925 dan bawang merah sebanyak 506,2 ton. Perubahan penawaran tahun 2015-2019, yaitu terung panjang 32, 83 ton, mentimun -51,43 ton, tomat 86,23 ton, buncis 122,13 ton dan bawang merah 64,5 ton. Total harga per Kg produk hortikultura (ton) menurut Provinsi NTT  tahun 2015-2019 adalah, produk terung panjang Rp.18.997, mentimun Rp.14.832, tomat Rp. 26.896,00, buncis Rp. 20.478 dan bawang merah Rp.63.789. Rerata elastisitas penawaran produk hortikultura di Kabupaten Manggarai tahun 2015-2019 yaitu, produk terung panjang 85,1 (Elastisitas), mentimun 63,6 (Elastisitas), tomat 6,8 (Elastisitas), buncis 5,1 (Elastisitas) dan bawang merah 236,0 (Elastisitas).
Pengujian Daya Berkecambah dengan Metode Pengujian dan Suhu yang Berbeda
Authors: Jawak Gani , Juharni
Published: July 2024

The proper germination testing method is an absolute condition that must be met in determining the viability of seeds. Seed viability is one of the mandatory tests carried out in determining the quality of seeds to be circulated. This study aims to study germination testing methods related to growing methods and media, temperature and evaluation time of germination from several types of seeds. The study consisted of two sub-topics, namely (1) Germination growth at different test methods and (2) Germination rate at two different temperatures. Experiment 1 used cucumber, caisin, and peanut seeds while the second experiment used corn and onion seeds. Cucumber seeds were tested by 3 methods, namely UKDdp, UDK, and UAK; caisin seeds tested by 1/2 UKDdp and UDK methods; peanut seeds tested by sand and UKDdp methods; corn and onion seeds tested by UKDdp method placed at room temperature and constant. Cucumber, caisin and peanuts are placed on the ecogerminator. Each treatment is repeated 9 times, each replay of 25 grains of seeds. Observations were made on the parameters of germination power and sprouting speed with the observation time referring to the ISTA rules. Cucumber seed data were analyzed with RAL one factor while other plant seeds used t-student. In cucumber seeds, the UKDdp and UAK methods are the best methods in the DB test although they are not significantly different from UDK. In caisin seeds the 1/2UKDdp method is the best method in the germination test and in peanut seeds, the best method in the germination test is UKDdp and sand. Room temperature and constant temperature can be used for corn DB test but growing speed is higher at room temperature. Constant temperature testing is best for onion DB testing with better growing speed than room temperature.
Strategi Pengembangan Usahatani Kubis di P4S ST. Yohanes Berkhmans Malanuza
Authors: Lanas Romanus Ronaldo , Agun Lusiana Putriani , Bana Maryance Vivi Murnia , Cordanis Astried Priscilla
Published: July 2024

Kubis merupakan salah satu tanaman pertanian dengan nilai ekonomis yang cukup tinggi yang dapat dimanfaatkan untuk berbagai industri dan segala kebutuhan manusia. Permasalahan utama yang dihadapi dalam usahatani kubis adalah permodalan, teknologi modern, persoalan pupuk, serangan hama dan penyakit, pengaruh cuaca dan iklim serta proses pemasarannya. Penelitian ini dilakukan untuk mengetahui faktor internal dan eksternal dalam usahatani kubis dan bagaimana strategi pengembangan usahatani kubis. Metode yang digunakan adalah analisis deskriptif menggunakan tabel IFAS dan EFAS kemudian di interprestasikan ke dalam diagram analisis SWOT menggunakan indeks skor, lalu alternatif strategi dapat dilihat di Matriks SWOT. Hasil analisis menunjukkan bahwa faktor internal usahatani kubis di P4S St. Yohanes Berkhmans Malanuza terdapat lima kekuatan (Strength) dan lima kelemahan (Weakness). Untuk faktor eksternal terdapat lima peluang (Opportunity) dan lima ancaman (Threat). Nilai IFAS sebesar 2,49 dan nilai EFAS sebesar 2,65.
Kata Kunci: Analisis SWOT, EFAS, IFAS, Kubis, Strategi Pengembangan
Respon Komponen Hasil Kedelai (Glycine max. L(MERR) Varietas Anjasmoro terhadap Pemberian Kompos Jerami
Authors: Haim Kristina , Seratu Filomena , Liana Devi
Published: July 2024

Tanaman kedelai termasuk tanaman yang peka terhadap kondisi lingkungan tumbuh sehingga berpengaruh terhadap komponen hasil kedelai. Tujuan dari penelitian ini  adalah untuk mengetahui respon komponen hasil kedelai terhadap pemberian kompos jerami padi. Penelitian ini dilaksanakan di Kelurahan Tenda Kecamatan Langke Rembong, Kabupaten Manggarai. Lahan yang dipakai  untuk melakukan penelitian ini merupakan lahan milik Kampus Unika Santu Paulus Ruteng. Penelitian dilaksanakan pada bulan Maret- Juli 2021. Rancangan yang digunakan dalam penelitian ini adalah Rancangan Acak Kelompok (RAK) faktor tunggal yang terdiri dari empat perlakuan yaitu kontrol, kompos jerami padi 240 g/polybag, kompos jerami 480 g/polybag dan kompos jerami 720 g/polybag, yang terdiri dari tiga ulangan. Hasil penelitian menunjukkan bahwa respon  komponen hasil kedelai terhadap pemberian kompos jerami padi tidak berbeda nyata dengan komponen hasil kedelai kontrol (tanpa perlakuan). Hal tersebut dipengaruhi oleh kondisi lingkungan tumbuh yang kurang optimal sehingga komponen hasil kedelai tidak berbeda nyata.
Pengaruh Pemberian Pupuk Organik Cair Batang Pisang terhadap Pertumbuhan dan Hasil Tanaman Cabai Merah Keriting (Capsicum annuum L.)
Authors: Fideri Framblianus , Knaofmone Elfrida , Purba Dumaris Priskila
Published: July 2024

Curly red chili plant (Capsicum Annuum L.) is one of the seasonal fruit vegetable plants that has woody stems, has a distinctive taste and aroma as a food flavoring so that it is much loved by the public. Efforts made by farmers to in.crease their agricultural production by applying liquid organic fertilizer. Liquid organic fertilizer (LOF) is a type of fertilizer that can be used to increase the productivity of agricultural commodities. The purpose of this study was to determine the growth respons of curly red chilies to the administration of LOF banana stems and also to determine the best dose LOF banana stems to the growth curly red chilies (Capsicum annum L.). The research method used was a randomized block design (RBD) with one factor, namely the dose of LOF banana stems (P), which consisted of 6 treatments and 3 replications. In each group, there were 12 plants, and 6 plants which were sampled for observation. The 6 treatments were as follows, (1) without treatment/control, (2) 100 ml LOF banana stems/900 ml water, (3) 200 ml LOF banana stems/800 ml water, (4) 300 ml POC banana stems/700 ml, (5) 400 ml LOF banana stems/600 ml water, and (6) 500 m500 ml LOF of banana stems.The result showed that the application of LOF banana stems to the growth of curly red chili plants did no significantly affect plant height, number benanaof leaves and number of flowers. However, the provision of LOF banana stems had asignificant effect on fresh fruit weight of the first harvest and fresh fruitweight of the second harvest. In this study the best dose was found in the P5 treatment with a dose of 500 ml banana stem LOF. This is presumbaly because the LOF banana stems contains the nutriensts needed by plants.
KETERATURAN ANC TERHADAP PERSALINAN NORMAL
Authors: Sari Anjelina Puspita , Romlah Romlah , Sartika Silaban Titin Dewi
Published: July 2024

Indikator dari kesehatan yang meningkat ditinjau dari angka kematian ibu (AKI). AKI merupakan prevalensi suatu kejadian jumlah kematian setiap tahunnya pada setiap perempuan yang melahirkan. Data sampling registration system sekitar 76% kematian ibu terjadi saat fase persalinan dan pasca persalinan. Banyak faktor yang mempengaruhi atau yang menyebabkan terjadinya komplikasi pada setiap persalinan yang dampaknya mengakibatkan kematian pada ibu, oelh karena itu pemerinta membuat beberapa program, salah satunya meningkatkan kesehatan ibu hamil. Penelitian ini bertujuan untuk mengetahui hubungan keteraturan ANC terhadap persalinan normal. Penelitian ini menggunakan jenis penelitian analitik obsevasional dengan desain cross sectional. Teknik pengambilan sampel pada penelitian ini yaitu total sampling, dengan jumlah sampel berjumlah 50 responden. Data diambil dengan observasi data retrospektif yaitu dengan mengambil catatan medik responden. Analisa dalam penelitian ini menggunakan uji Chi-Square. Hasil uji statistik didapatkan bahwa ada hubungan yang signifikan antara keteraturan ANC terhadap persalinan normal dengan nilai p-value = 0.003. kesimpulan dalam penelitian ini bahwa keteraturan antenatal care mempengarahui jenis persalinan yang akan dilakukan pada setiap ibu. Disarankan ibu hamil harus rutin melakukan kunjungan ANC agar dapat mempertahankan kenormalannya sampai persalinan, nifas dan menyusui.
HUBUNGAN PENGETAUAN, MASA KERJA DAN PENGAWASAN TERHADAP PERILAKU PEMILAHAN LIMBAH MEDIS PADA TENAGA KESEHATAN DI RUMAH SAKIT HERMINA DEPOK TAHUN 2023
Authors: Salamah Nurul Pitriani , Nina Nina , Yaser Mohammad
Published: July 2024

Pendahuluan: Memilah limbah dilakukan mulai dari sumber yang menghasilkan limbah, limbah benda tajam dikumpulkan dalam satu wadah dengan mempertimbangkan apakah terkontaminasi atau tidak, dan limbah medis padat digunakan kembali melalui proses sterilisasi. Tujuan dari penelitian ini adalah Untuk Mengetahui Hubungan Pengetauan, Masa Kerja Dan Pengawasan Terhadap Perilaku Pemilahan Limbah Medis Pada Tenaga Kesehatan Di Rumah Sakit Hermina Depok Tahun 2023 . Metode: Penelitian ini merupakan penelitian kuantitatif dengan menggunakan pendekatan cross sectional . Populasi dalam penelitian ini yaitu tenaga kesehatan seperti perawat , bidan dan farmasi yang bekerja di Rumah Sakit Umum Hermina Depok dengan jumlah 201 tenaga kesehatan dan menggunakan pengambilan sampel yang digunakan dalam penelitian ini menggunakan teknik Accidental Sampling dan diperoleh sampel tenaga kesehatan sebanyak 134 responden. Hasil: penelitian menunjukkan ada hubungan pengetahuan dengan p value sebesar 0,003 (p<0,05) dan OR=2,958 , tidak ada hubungan masa kerja dengan p value sebesar 0,181 (p>0,05), dan  ada hubungan antara pengawasan dengan p value sebesar 0,001 (p>0,05) dengan perilaku pemilahan limbah medis pada tenaga kesehatan. Kesimpulan: keseluruhan dapat disimpulkan bahwa kondisi Tenaga Kesehatan di RSU Hermina Depok mengenai pengetahuan perlu mendapatkan pelatihan atau sosialisasi yang memadai tentang memilah limbah medis. Pelatihan ini harus mencakup prosedur, peraturan, dan pedoman yang berlaku untuk memilah dan pengelolaan limbah medis. Hal ini mengakibatkan dari kurangnya pengetahuan tenaga kesehatan dalam memilah limbah di rumah sakit dapat sangat serius dan berdampak negatif pada lingkungan salah satu dampak utama dari memilah limbah yang kurang baik adalah pencemaran lingkungan, resiko cedera, biaya tambahan pada rumah sakit. Berkaitan dengan pengawasan pada limbah medis bahwa pengawasan yang efektif terhadap memilah limbah medis di rumah sakit sangat penting untuk menetapkan bahwa proses pemilahan, penanganan, dan pengelolaan limbah medis berjalan sesuai aturan dan SOP yang berlaku.
Are Chinese University Students Ready for Autonomous English Listening Practice?
Authors: Luu Thi Mai Vy , Lu Jinming
Published: July 2024

Given the growing emphasis on autonomous learning within language education, comprehending students’ perspectives, incentives, and cognizance about autonomous listening becomes imperative for the formulation of effective pedagogical approaches. This study seeks to examine the readiness of Chinese university students to engage in autonomous English listening practice. The research employed a questionnaire-based methodology administered to a sample of 200 Chinese university students. The survey focused on gauging students’ perspectives on autonomous English listening practice, examining their level of motivation, and assessing their awareness of their capabilities in handling autonomous listening. The study revealed that Chinese university students generally recognize the prospects and promises of autonomous English listening. Notably, students exhibited increased motivation for autonomous listening provided that they were given teacher guidance and a certain level of pressure. Additionally, the findings indicated that students possess a relatively high level of awareness regarding their capabilities to engage in autonomous listening practices. This research contributes to the literature on language education by providing insights into the readiness of Chinese university students for autonomous English listening practice. The identified factors influencing motivation and awareness shed light on the potential success of implementing autonomous listening strategies. Educators and policymakers can benefit from these findings to enhance English listening instruction methodologies and better meet the needs of students in the ever-evolving landscape of language education.
ANALISA PERBANDINGAN PENGGUNAAN LAMPU TL, CFL DAN LAMPU LED (STUDI KASUS PADA APARTEMEN X)
Authors: Chumaidy Adib
Published: July 2024

ABSTRAKApartemen X merupakan sebuah bangunan yang didalamnya terdiri dari area parkir atau basement,ruang ME (ruang kontrol panel), tangga kebakaran atau evakuasi, utilitas, fasilitas publik (lobby lift), koridorapartemen, ruang ganti, unit hunian apartemen. Sumber penerangan harus memenuhi standar dan disesuaikandengan indera penglihatan manusia, demi memberikan kenyamanan dalam berbagai aktifitas.Untuk itu dalammenghitung jumlah kebutuhan lampu yang terpakai dari lampu TL, CFL dan LED, dihitung berdasarkan besarnilai lux pada suatu ruangan, luas ruangan, nilai lumen, nilai effisiensi penerangan dan faktor depresiasi ataunilai pengurangan pengotoran lampu, nilai cos phi atau cosinus beban lampu.Dari hasil perhitungan untuk pemakaian energy listrik pada sebuah apartemen, diperlukan energylistrik sebesar 508,47MWh untuk lampu LED, sedang untuk lampu TL elektronik 682,9 MWh per tahun. Dengandemikian penggunaan lampu LED lebih hemat 25,54 % dibandingkan lampu TL elektronik
Rancang Bangun Kalibrator Elektrokardiogram
Authors: Olivia Willa , Ahmad Arfian
Published: July 2024

Abstrak-Elektrokardiogram (EKG) adalah alat diagnostik yang dapat merekam aktivitas kelistrikan jantung. Tidakpresisinya peralatan EKG akan menyebabkan hasil perekaman aktivitas kelistrikan jantung yang tidak akurat.Akibatnya akan terjadi kesalahan dalam membaca hasil yang akan berakibat kesalaham dalam menentukandiagnosa penyakit. Untuk itu, secara berkala peralatan EKG harus dikalibrasi agar keakurasian pembacaannyaterjamin. Oleh sebab itu dirancang-bangun suatu alat untuk kalibrasi EKG yang lebih umum disebut KalibratorEKG. Dari hasil rancang-bangun tersebut dihasilkan kalibrator EKG dengan tingkat kesalahan yang kecil, yaitusebesar 0,25% dan tingkat keakurasian yang tinggi yaitu sebesar 99,75%. Dengan demikian kalibrator EKGyang dirancang-bangun ini bisa digunakan sebagai Kalibrator Elektrokardiogram.