bluuebunny/crossref_metadata_2025 huggingface dataset:
GENDER PROGRESSIVE TEACHING IN PREMARITAL COURSE: Study on Islamic Marriage Guidance Books for Prospective Muslim Couples
Authors: Marwah Sitti
Published: April 2023

For more than two decades, the government has been attempting to pay attention to gender equality in Indonesia. However, these efforts have not been claimed successful. This paper examines the contents of the marriage guidance book for bride and groom, initiated by the Office of Religious Affairs. This paper aims to analyze the concept of equality defined in the book. The primary source of this study is the marriage guidance book, which has been referred to by the Ministry of Religious Affairs: (1) The Marriage Guidance Module for Bride and Groom, and (2) The Sakinah Family Foundation Book. The data is also collected through interviews. The analysis was conducted using a gender approach, which is aimed at mapping the type of relationship between men and women within the family in the course book. After conducting research, it is found that the Ministry of Religious Affairs collaborated with a number of experts on gender equality in drafting the books. Therefore, the concept of gender equality between husband and wife presented in the books shows a progressive understanding.[Lebih dari dua dekade pemerintah telah berupaya memberikan atensi terhadap wacana kesetaran gender di Indonesia. Akan tetapi upaya tersebut belum begitu berhasil. Tulisan ini mengkaji tentang isi buku tuntunan perkawinan bagi calon pengantin yang digagas oleh Kantor Urusan Agama. Tulisan ini bertujuan untuk menganalisis konsep kesetaraan yang didefinisikan dalam buku tersebut. Sumber utama penelitian ini adalah buku pedoman perkawinan yang dirujuk oleh Kementerian Agama. Buku-buku tersebut adalah (1) Modul Bimbingan Nikah untuk Pengantin, dan (2) Buku Yayasan Keluarga Sakinah. Data tersebut juga dikumpulkan dengan wawancara. Analisis dilakukan dengan menerapkan pendekatan gender, yang bertujuan untuk memetakan bentuk relasi antara laki-laki dan perempuan dalam kursus perkawinan. Setelah melakukan penelitian, penulis menemukan bahwa Kementerian Agama bekerjasama dengan sejumlah pakar kesetaraan gender dalam penyusunan buku tersebut. Oleh karena itu, konsep kesetaraan gender antara suami dan istri yang disajikan dalam buku-buku tersebut menunjukkan pemahaman yang progresif.]
WHEN RELIGIOUS JUDGES PROTECT CHILDREN'S RIGHTS: Case of Divorce in Padangsidempuan Religious Court
Authors: Ahmatnijar Ahmatnijar , Tenrilawa Dian Furqani , Asmuni Asmuni , Matsum Hasan , Subha Rahman
Published: April 2023

In a marriage, a parent is the primary party that fulfills children's rights, but in reality, not all marriages end in ideal conditions. In many divorces, children's rights are jeopardized. This paper aims to study how children's rights are fulfilled at the hands of the Padangsidimpuan Religious Courts. Data for this study were collected through in-depth interviews, while secondary data was obtained from the case register files at the Padangsidimpuan Religious Court. After conducting research, it was found that the majority of wives who filed for divorce at the Padangsidimpuan Religious Court mostly did not include the rights of the children in their petition. In deciding this case, the judge at the Padangsidimpuan Religious Court followed existing regulations. The verdict always refers to the posita. However, apart from that, many judges also advise the litigants to include children's rights in the posita lawsuit therefore their rights can be protected by a judge's decision.[Dalam sebuah perkawinan, orang tua seharusnya menjadi pihak utama yang memenuhi hak-hak anak, tetapi ternyata tidak semua pernikahan baik-baik saja. Banyak terjadi perceraian yang mengancam hak anak. Tulisan ini bertujuan untuk mengkaji bagaimana terpenuhinya hak-hak anak di Pengadilan Agama. Data dalam penelitian ini dikumpulkan dengan cara melakukan wawancra mendalam, sedangkan data sekunder diperoleh dari berkas-berkar register perkara di Pengadilan Agama Padangsidimpuan.  Setelah melakukan penelitian didapatkan fakta  bahwa mayoritas istri yang mengajukan gugatan cerai di Pengadilan Agama Padangsidimpuan hanya mengajukan gugat cerai belaka tanpa turut menyertakan hak anak yang di bawah pengasuhannya.Hakim Pengadilan Agama Padangsidimpuan dalam memutuskan hal tersebut konsisten dengan regulasi yang ada. Putusan selalu merujuk posita. Namun ternyata selain itu, banyak juga hakim yang menyarankan kepada pihak yang berperkara untuk memasukkan hak-hak anak dalam posita gugatan agar dapat dilindungi haknya oleh putusan hakim.]
NOT ONLY FOR BEAUTY BUT ALSO FOR A BETTER FUTURE: The Ritual of Potong Konde at the Wedding Reception among Muslims of Gunung Meriah Aceh
Authors: Khairuddin Khairuddin , Hidayah Nur
Published: April 2023

This article discusses the meaning of cutting konde (back hair) for the bride among the Muslims of Gunung Meriah. Cutting konde is usually held at the wedding reception. Data were collected through observation and interviews. Based on empirical research, it can be stated that cutting the konde for the bride among the people of Gunung Meriah Aceh is part of the customary law on marriage. Physically, cutting konde aims to beautify the bride's hair and eyebrows. Besides that, the ceremony is also meant to foresee the future of the household that will be experienced by the bride and her children. If the forecast results in an unexpected outcome, the community will conduct collective prayer. In Islamic law, this practice has no theological justification. Even though they are aware that this practice is not part of Islamic teachings, the Muslims of Gunung Meriah Aceh continue to practice it because they believe that, by doing so, they will be aware that bad luck can happen and that, in the future, they will not be surprised.[Artikel ini membahas tentang makna potong konde bagi pengantin wanita di kalangan umat Islam Gunung Meriah Aceh. Pemotongan konde biasanya dilakukan pada acara resepsi pernikahan (walimat al-'ursy). Data dikumpulkan melalui observasi dan wawancara. Berdasarkan penelitian empiris dapat disimpulkan bahwa pemotongan konde untuk mempelai wanita di kalangan masyarakat muslim Gunung Meriah merupakan bagian dari hukum adat perkawinan setempat. Secara fisik, pemotongan konde bertujuan untuk memperindah rambut dan alis pengantin. Selain itu, upacara tersebut juga dimaksudkan untuk meramalkan masa depan rumah tangga yang akan dialami oleh mempelai dan keturunannya. Jika ramalan tersebut menghasilkan sesuatu yang tidak diharapkan, maka masyarakat akan melakukan doa secara berjamaah. Dalam hukum Islam, praktik ini tidak memiliki pembenaran teologis. Meski sadar bahwa praktik tersebut bukan bagian dari ajaran Islam, namun umat Islam Gunung Meriah Aceh tetap melakukannya karena meyakini dengan melakukan itu, mereka akan sadar sbahwa kesialan bisa saja terjadi di masa depan, dan jika terjadi mereka tidak akan terkejut.]
A Model of Inclusive Education Curriculum in Islamic Education Institutions: A Case Study in Banten Province, Indonesia
Authors: Ilyas Elis Lisyawati , Setyaningrum Nur , Sumarni Sumarni
Published: April 2023

Purpose – The objective of this study was to describe and analyze the inclusive education curriculum model according to the Decree of the Director General of Education in 2016.

Design/methods/approach – Qualitative descriptive methods in this study were used to describe the use of the inclusive curriculum model thoroughly and empirically in Islamic schools (Madrasah). In-depth interviews, observation, and document studies are used to collect field data using triangulation to conclude.

Findings – Based on the field data results, the development of the curriculum for the four Madrasahs which were the target of research adapted more show duplication by modifying some of its elements/items/components. No fully modified curriculum components were found but only learning strategies or approaches based on the needs and conditions of students with special needs. This has an impact on the potential development of children with special needs who are not yet optimal.

Research implications/limitations – This research was conducted in 4 Madrasah in Banten Province. There are 18 Madrasah in other provinces which have become pilot projects for inclusive education.

Originality/value – The maximum development of a student’s potential can be made possible by various other development models, such as modification, substitution, and omission.
PAI Teacher Strategy in Improving Learning Effectiveness in Limited Face-to-Face Learning
Authors: Radino Radino , Permatasari Lia Fatika Yiyi
Published: April 2023

Purpose – The purpose of this study was to find out PAI and Budi Pekerti Teachers' Strategies in preparing the planning, implementation, methods, and media used as well as evaluating PAI and Budi Pekerti learning to develop the effectiveness of learning in limited face-to-face learning at SMK N 1 Depok.

Design/methods/approaches –This research is descriptive qualitative.   It involved 3 research subjects, Islamic Religious Education and Moral Education subject teachers for class X, with 20 informants from class X TB students. The data were collected through interviews, observation, and documentation. Data validation technique was done with triangulation technique. Data analysis techniques with data reduction (data selection), data display (data presentation), and conclusion drawing/verification (drawing conclusions).

Findings – The results of the study show that: The PAI and Budi Pekerti teacher's strategy in developing the effectiveness of learning in limited face-to-face learning at SMK N 1 Depok is quite effective, PAI and Budi Pekerti teachers prepare learning by the following steps i.e, 1) Making lesson plans based on the syllabus, 2) Preparing material 3) Preparing simple learning media. The teacher's strategy for PAI and Budi Pekerti in carrying out learning to develop learning effectiveness is to carry out learning by paying attention to learning time, the teacher's role as a motivator. Applying appropriate learning methods and providing simple media, PAI Teacher Strategies and PAI and Budi Pekerti characteristics in evaluating learning to develop limited face-to-face learning at SMK N 1 Depok with daily assessments, mid test, and final test.

Research implications/limitations – This research has implications for the teacher's strategy in limited face-to-face learning to increase learning effectiveness.

Originality/value – This study provides a real picture of the limited face-to-face learning implementation of PAI.
Influence of Religious Intellectual Humility (IH) in the Learning Process Shapes Student Tolerance Behavior
Authors: Pelupessy Muhammad Kashai Ramdhani , Abidin Andi Rahmat , Pattimahu M. Asrul
Published: April 2023

Purpose –Understanding of religious extremism has begun to enter the world of campuses in Indonesia today. Of course, this has an impact on intolerance behavior. Recent studies show that religious intellectual humility (IH) can shape a person's tolerant behavior. But so far, this topic has been minimally replicated in the learning process in Indonesia. Therefore, this research seeks to prove and explain the influence of religious IH in the learning process in shaping students' tolerant behavior.

Design/methods/approach–This study is an ex-post facto research. The subjects were lecturers (29 people) and students (41 people) at Islamic Education Department (IED) from one of the Islamic universities in Maluku. Data collection techniques use the IHS scale, RHS, and tolerance behavior scale. Data analysis used a simple linear regression technique.

Findings –The results of the study show that there is an influence of religious IH in the learning process to shape student tolerance behavior by p = 0,000 (p<0,05). The contribution of religious IH forms tolerance behavior of 76.2%. This means that apart from religious IH, around 23.8% of other variables also shape tolerant behavior such as empathy, self-disclosure, and giving support for the rights of others.

Research implications/limitations –The limitation of this research is that the subject comes from a limited number of lecturers and students in Maluku. In addition, this study also did not use an experimental design. It is suggested that the next study needs to involve a large number of samples (educators and students), it is also expected that it needs to be replicated in the form of an experimental design.

Originality/value –This study recommends educators (lecturers) continue to practice religious IH in the learning process, especially for their students (prospective IED teachers) so that later they can practice it in the IED learning process in the future.
The Long Road to Social Inclusion: Participation of Vulnerable Groups in Village Development
Authors: Ro'fah Ro'fah , Hanjarwati Astri , Suprihatiningrum Jamil
Published: April 2023

The Indonesian village Law No. 6/2014 has set the tone for empowering local development, establishing village as a local democratic institution with the ability to manage its own development. It is explicitly stated in the law that one of its goals is to establish the village community as a subject instead of an object of development. Therefore, the law highly encourages civic participation. While the mechanism is in place to ensure the participation of village inhabitants, the participation of marginalized groups such as women, people with disabilities, and eldery remain unexplored. Using interviews with the marginalized groups in four villages in Indonesia, the aim of this paper seeks to capture the dynamic participation of this population and to examine the barriers to their participation in the development process. In this study, it was found that meaningful participation has not yet been achieved, thus, there is still a need to advocate for empowerment for this population. In addition, marginalized groups continued to experience challenges and barriers in to their participation, primarily due to the absence of a structure and mechanisms that specifically address their need. These include the absence of disability or women organizations or forums, the inaccessibility of information, and the lack of awareness of village government to include marginal groups.
La narrativa del rock y el metal en Colombia: Aproximación a un género musical a través de seis novelas
Authors: Sierra Amortuegui Diego Armando
Published: April 2023

A través del análisis literario, podemos trazar unared infinita de símbolos, ideologías y microsemióticas que movilizan las relaciones entre el mundo y los autores. La música comparte muchos de estos rasgos simbólicos y, por ello, la literatura urbana la ha incorporado como base sonora de sus narraciones. A la luz de la teoría literaria y de la sociocrítica, exploramos la literatura roquera constituida por seis novelas escritas en Colombia, que toman el Rock y sus subgéneros dentro de la base argumental y temática de las obras. En este sentido, definimos La narrativa del rock y el metal en Colombia como un conjunto de obras literarias que exploran de manera particular la estética y la cultura del rock. Literatura que expande las convenciones del género a través de la representación de ideologías, símbolos y marcas rituales que revelan la cosmovisión de los autores
Imagen sexual de la vejez: Análisis del cuerpo desnudo femenino en la película Japón de Carlos Reygadas
Authors: López Betanzos Inés Marisela
Published: April 2023

Este artículo presenta un análisis del cuerpo de Ascensión, una mujer anciana que aparece desnuda en una escena sexual de la película Japón (2002) del director mexicano Carlos Reygadas. El cuerpo de Ascensión no coincide con el signo de belleza representado en películas del cine clásico ni se caracteriza como un cuerpo para ser visto en el arte. Así pues, el análisis se realiza con una propuesta metodológica que parte desde la perspectiva del feminismo y los estudios visuales para reconocer si se trata de una imagen cuyos significados corresponden con las construcciones del cuerpo femenino en el patriarcado
El Discurso Celebratorio de Maladrés: la jugada doble que no lleva a ningún fin
Authors: Cáceres Jaramillo Juan Fernando
Published: April 2023

Entre los discursos y conferencias que conforman la cátedra Prácticas del Fracaso, impartida por el Afamado Clown Maladrés en la Maestría de Estudios Artísticos de la Universidad Distrital Francisco José de Caldas, se encuentra el Discurso Celebratorio, texto que sirve de abrebocas para la avalancha de los aspectos tanto teóricos como performáticos que configuran dicho laboratorio. El juego que, en este caso, propone este célebre orador pareciera, en un principio, apuntar hacia un terreno infértil pero que, si se mira minuciosamente, contiene elementos que anuncian aspectos tanto epistemológicos como metodológicos de aquello que el payaso denomina malpensamiento. Se hace, entonces, una aproximación a dicho discurso a la luz de la intervención de otro discurso, esta vez derridiano, con el fin de desentramar la intención que, desde lo irónico, plantea este payaso/docente.
Pantallas de la liberación. Las tecnologías lugarizadas de la América profunda
Authors: Aguilar Gómez Diego Andrés
Published: April 2023

Dada la condición tan extendida y naturalizada en nuestro mundo embebido de tecnologías mediada por las “bellas pantallas”, se plantean las siguientes preguntas centrales de investigación: ¿Es posible decolonizar la tecnología de las pantallas a partir de un pensar/hacer/sentir particular y transdisciplinar que emerge lugarizadamente desde la periferia de la América Profunda colombiana? Y, ¿Cómo sería posible realizar esta decolonización particular, a partir de la puesta en praxis de pantallas holográficas y de tecnologías construidas desde el territorio como modos de construcción epistémica y de creación “aiesthésica”?
Conversaciones y Plegarias (2019-2022) de Rosario López: el territorio textil en un encuentro de dos mundos
Authors: Montalvo Senior María Camila
Published: April 2023

A través de las obras de la artista Rosario López, Conversaciones y Plegarias (2019-2022), que hacen parte de la exposición “El mapa no es el territorio” (2022) en la Mmaison Galería en Bogotá, se abre un espacio de encuentro de dos cuerpos y de dos mundos: el de la mujer indígena y el de la mujer burguesa de ciudad. Ambas figuras feminizadas tejen y se encuentran entre rutas y mapas textiles, reconfigurando una ciencia interpelada por el mito y un arte contemporáneo que nace del territorio, de la tierra y de una conversación con la selva en la serranía de La Lindosa en Colombia. Lo anterior pone en jaque dos tipos de patriarcado: uno precolombino dado por el Yuruparí y un colonial de las sociedades hegemónicas occidentales. Además, la obra busca recuperar y valorar el conocimiento intelectual y artístico de las mujeres dentro de una franja de tiempo de 20.000 años de historia.
Can Breaking Heroin Addiction Lead to a Broken Heart? A Case of Reverse Takotsubo Cardiomyopathy in a Patient With Heroin Withdrawal
Authors: Launer Hunter , Nelson Daniel , Dietzen Alarica , Singla Atul
Published: April 2023

Reverse takotsubo cardiomyopathy is triggered by emotional or physical stress and has a presentation similar to that of acute coronary syndrome. A 39-year-old woman with a history of heroin use disorder presented with intractable nausea, vomiting, and diarrhea. She was diagnosed with heroin withdrawal and started on buprenorphine-naloxone. On day 2 of her hospitalization, she developed chest heaviness and had an elevated troponin I level of 3.2 ng/mL (reference range, 0.015–0.045 ng/mL); electrocardiography showed new T-wave inversions in the anterior and inferior leads. Emergent coronary angiography showed patent coronary arteries, and left ventriculography showed basal hypokinesis and apical hyperkinesis, consistent with reverse takotsubo cardiomyopathy secondary to heroin withdrawal. She was started on antihypertensive agents, and her buprenorphine-naloxone dose was increased. At her 3-month follow-up visit, she reported no symptoms consistent with angina or heart failure. This appears to be the first report of heroin withdrawal causing reverse takotsubo cardiomyopathy. Awareness of this association can lead to earlier recognition and treatment of reverse takotsubo cardiomyopathy.
RELATIONSHIP BETWEEN LEUKOCYTE COUNT AND PROTEINURIA IN COVID-19 PATIENTS
Authors: Setiorini Anggar , Samsuria Indranila Kustarini , Retnoningrum Dwi , Ariosta Ariosta
Published: April 2023

Background: Coronavirus Disease 2019 (COVID-19) is a disease caused by SARS-CoV-2 with flu-like symptoms that could be serious in high-risk individuals. The use of laboratory parameters is determined as a predictor in improving the quality of care and thereby reducing mortality and morbidity. One of the laboratory parameters itself is hematological examination, including leukocyte count. Several studies had shown that an increase in WBC count was independently associated with an increased risk of proteinuria.Aim: To determine the relationship between leukocytes and proteinuria in COVID-19 patients.Method: This cross-sectional study with retrospective data collection had a sample of patients with COVID-19 at Diponegoro National Hospital aged 19-60 years. The independent variable in this study was leukocyte count, while the dependent variable in this study was proteinuria. The type of data used was secondary data obtained by examining the medical records of COVID-19 patients. Data analysis between leukocyte count and proteinuria variables in patients with COVID-19 was tested using a bivariate chi-square analysis.Results: Samples that met the inclusion criteria were 34 samples with confirmed COVID-19. From the results of the chi square test, it was found that leukocytes to proteinuria had a p value of 0.601 (p>0.05), which meant that there was no significant relationship between the number of leukocytes and proteinuria.Conclusion: There was no significant relationship between leukocyte count and proteinuria in patients with COVID-19.
A 52-Years Old Male Patient With Aorta Regurgitation Et Causa Rheumatic Heart Desease In Cut Meutia Regional General Hospital
Authors: Savitri Yuri , Mendrofa Jauza Raudhatul Jannah
Published: April 2023

Rheumatic heart disease (RHD) is an acquired heart disease with heart valve disorder that persists due to previous acute rheumatic fever, mainly affecting the mitral valve (75%), the aorta (25%), rarely affecting the tricuspid valve, and never affecting the valves lungs. A 52-year-old male patient, domiciled in Mutiara (Alue Awe) Lhokseumawe City, Indonesia. Come for outpatient treatment at Polyclinic of Cut Meutia Hospital. Patients are who routinely go to the polyclinic every month to take medicine. The patient complains of left chest pain, shortness of breath, heart palpitations, cough, tired easily during activities, especially during strenuous activities. History of Diabetes Mellitus is denied, history of hypertension (+). The patient admitted that he was diagnosed with rheumatic heart disease at the age of 19 years. The patient has been undergoing treatment for 33 years by routinely complete checks related to his heart every year and regularly taking medication at the polyclinic every month. The patient admitted at junior high school age he often experienced attacks of fever that went up and down accompanied by pain in the throat. Physical examination found: Compos Mentis (E4V5M6), BP:140/40 mmHg, HR : 92x/i, RR: 23x/i, T; 37.1°C, SpO2 : 95%. Chest examination showed vesicular breath sounds, Rhonki (-), Wheezing (-), Diastolic murmur (+).Echocardiography showed an EF of 70%. AR Severe, MR Moderate. AML Prolapse, Calcification (+), LV Dilatation, LVH Eccentric
The Effect of Duration of Administration and Discontinuation of Fluorometholone Eye Drops on The Trabecular Meshwork
Authors: Muslim Sandi , Saubig Arnila Novitasari , Prihatningtias Riski , Sulakso A. Kentar Arimadyo , Rahmi Fifin Luthfia
Published: April 2023

Background: The extracellular matrix (ECM) in the trabecular meshwork (TM) may play a role in the steroid-induced aqueous humor outflow resistance pathophysiology. Topical steroids such as fluorometholone can cause elevated intraocular pressure. Increased synthesis and accumulation of TM ECM proteins due to steroids result in TM dysfunction and elevated intraocular pressure.Purpose: This study aims to analyze the effect of duration of administration and discontinuation of fluorometholone eye drops on the thickness of the TM ECM of Wistar rats.Methods: This study was an experimental study with a posttest-only control group design. The total sample of 25 rats was divided into 5 groups: Treatment 1 was given topical fluorometholone for 4 weeks and stopped for 4 weeks. Treatment 2 was given fluorometholone for 6 weeks and stopped for 4 weeks. Control 1 was given topical fluorometholone for 4 weeks, Control 2 was given topical fluorometholone for 6 weeks, and the negative control was used as a baseline. TM ECM examination was assessed using histopathological score grading. This study used the Mann-Whitney test and the Kruskal-Wallis comparative hypothesis test.Results: The difference in ECM thickness was not statistically significant either between treatment group 1 and treatment group 2 (p=1.000) or control group 1 (p=0,1000). There was a significant change in the thickness of the TM ECM in treatment group 1, treatment 2, control 1, control 2 compared to the negative control (p=0.003, p=0.003, p=0.003, p=0.004).Conclusion: TM ECM thickness did not return to normal thickness after administration of fluorometholone eye drops one drop 4 times a day for 4 weeks and 6 weeks followed by discontinuation of the drug for 4 weeks. The thickness of the TM ECM was thicker in experimental rats with a longer duration of administration of fluorometholone eye drops.
The Effect of Tempeh gembus on Malondialdehyde and Superoxide Dismutase Enzyme Levels in Rats with Diet-Induced Metabolic Syndrome
Authors: Rachmawati Pristina Adi , Afifah Diana Nur , Rustanti Ninik , Anjani Gemala , Juniarto Ahmad Zulfa
Published: April 2023

Background: High level of malondialdehyde (MDA) and low level of superoxide dismutase (SOD) are markers of oxidative stress and indicate enhance metabolic syndrome. Tempeh gembus is a food that has antioxidant properties which can decreased MDA concentration and increased SOD enzyme activity.Objective: The aim of this research was to determine the effect of Tempeh gembus on plasma MDA and serum SOD enzyme levels in metabolic syndrome rats.Methods: A post-test only experimental design was used in which 25 Sprague Dawley rats were divided into 5 equal groups of 2 control groups (K- and K+) and 3 treatment groups (P1, P2, P3). Metabolic syndrome was induced in the K+ control and the 3 treatment groups. Tempeh gembus were given for 4 weeks with the doses of 2.5g (P1), 5g (P2), and 7.5g (P3). Plasma MDA levels were measured by the Thiobarbituric Acid Reactive Substance (TBARS) method and serum SOD enzyme levels were measured by the Enzyme Linked Immunosorbent Assay (ELISA) method. The statistical analysis used One Way Anova test.Results: Tempeh gembus significantly decreased plasma MDA levels of metabolic syndrome rats (P=0.000) but had no significant effect on serum SOD enzyme levels in each treatment group (P=0.449).Conclusion: The dose of 7.5g Tempeh gembus was the most effective dose in reducing the plasma MDA level. Tempeh gembus in the 3 treatment doses significantly decreased plasma MDA levels but had no significant effect on serum SOD enzyme levels.
Comparison of Testosterone Undecanoate (TU) and Testosterone Enanthate (TE) with Combination of Depot Medroxyprogesterone Acetate (DMPA) on Spermatogenic Cells in Men
Authors: Dianty Retnaningtyas Siska , Midoen Yurnadi Hanafi
Published: April 2023

Introduction: Male hormonal contraception known as safe, effective, and reversiblecontraception. World Health Organization (WHO) multicentre study has been conducted aclinical study administrating of testosterone regimens and progestin to male with a remarkableresult. Azoospermia or severe oligozoospermia occurred in men with injection of TestosteroneEnanthate (TE) and Depot Medroxyprogesterone Acetate (DMPA) as well as TestosteroneUndecanoate (TU) and DMPA for a longer period. Decreasing gonadotropin as well astestosterone could lead to the amount of spermatogenic cells population declining by suppressingthe development of many kinds of cells. This narrative review was to compare howspermatogenic suppression in TE and TU with Combination of DMPA. Method: We arerandomly select article or journal from several databases and individual journal in certainkeywords. The keyword used were : (male hormonal contraception) OR (regimen testosterone))AND (progestin) OR (DMPA) OR (Testosterone enanthate) OR (Testosterone undecanoate) OR(male hormonal contraception combination)) AND (DMPA to spermatogenic cells) OR(Testosterone and DMPA to germ cell development)). After initial searching from databases andindividual journal website, 16 scientific articles or journals selected for the review. Result: Theresult indicated that injection of TE and DMPA had suppressed spermatogenesis, might notsuppressed sperm production for a longer period but the decreasing in type B spermatogoniauntil pachytene spermatocyte did occur. On the other hand, injection of TU and DMPA couldmaintain the suppression of sperm production for a longer period due to sustainable higher serumMPA with combination to even longer-acting TU would have more profound effect for that.Conclusion: It was known that combination of TU and DMPA might have better suppression onsperm production than TE and DMPA, otherwise further research needs to be obtained from thecombination of TU and DMPA on spermatogenic development and the association withintratesticular testosterone.
Case study of clinical improvement of atopic dermatitis in a patient treated with herbal-based parapharmaceuticals
Authors: Maraschio Andrea , Wulhfard Katya , Monsellato Luigi
Published: April 2023

Objectives

Atopic dermatitis (AD) is a chronic inflammatory skin disorder that has the immunoallergological characteristics of atopy and is characterised by itchy dermatitis with a recurrent-relapsing course and skin hyperreactivity. Official therapy involves topical anti-inflammatory and antimicrobial drugs for the skin but, as it is a recurrent and relapsing disease, the use of systemic anti-inflammatory and immunosuppressive drugs is eventually necessary to control the disease and prevent clinical exacerbation. However, systemic treatment may have a major impact on the patient, induce adverse reactions and not resolve the disease. The aim of the study is to establish whether the use of plant extracts may play a role in improving the quality of life of AD patients.

Case presentation

We describe the clinical case of a 27-year old Caucasian woman with dry, lichenified, slightly reddened and scaly skin lesions (EASI score 1.6), with anamnesis of atopy and multiple allergies, who was treated with an alternative therapeutic strategy to her previous ones, with three herbal-based parapharmaceuticals (Ribes nigrum L. buds, Piper longum L. fruits, Perilla frutescens L. Britton leaves and seeds in LUXFITOAL; Arctium lappa L. radix, Helychrisum italicum (Roth.) G. Don. flos, Viola tricolor L. herba cum floribus in LUXDERM; Trigonella foenum grecum seed extract, Hypericum perforatum extract in LUXTRIGONELLA cream). Two weeks after taking the drops and applying the cream the dry, lichenified skin lesions were no longer present and an eudermic state of the skin is restored (EASI score 0). Furthermore, six months after the beginning of the therapy, the good condition of the skin was maintained. The patient has never had such a long lapse of time without dermatitis reappearing on the anatomical sites observed at the first follow-up. After nine months, the patient was treated again for a dermatitis that had developed at another anatomical site, spreading frontally at the border between the lower margin of the neck and the upper margin of the thorax and at the chin (EASI value 3.2), achieving a marked improvement and a return of the eudermic state after two days (EASI value 0).

Conclusions

The patient was satisfied with the “clean hands” with no inflammation, with the resolution of the dermatitis in the other body sites and stated that the therapy has improved her perceived quality of life. These botanicals may be effective and play a role in improving the quality of life of a person with AD.
Use of a consortium to provide continuity in physician training: The OU-COM experience
Authors: Meyer Christopher T. , Portanova Ronald , Gevitz Norman , Dane Peter , Costello Walter , Parry Diane , Brose Jack , Ross-Lee Barbara
Published: April 2023

This article describes initiatives undertaken by the Ohio University College of Osteopathic Medicine (OU-COM) to develop a continuum of physician training that emphasizes the integration of basic sciences throughout undergraduate and graduate medical education. These initiatives demonstrate the effectiveness of consortia in actually restructuring educational programs, decreasing fragmentation, and promoting continuity.
Pericardial cyst: An incidental finding
Authors: Jarzabkowski Dory C. , Braunstein David B.
Published: April 2023

Pericardial cysts are rare mediastinal cysts occurring with an incidence of 1 in 100,000. Characteristically, they occur along the right border of the heart. Their size varies from 1.0 cm to 15 cm, and they are often asymptomatic. Patients with symptoms usually have atypical chest pain. In the case reported here, a 37-year-old man complained of nonproductive cough. Chest x-ray film revealed a pericardial cyst that appeared as a large echolucent unilocular mass along the left border of the heart. Diagnosis was confirmed with the use of both computed tomography and transthoracic echocardiography.
Serratia odorifera biogroup I: An emerging pathogen
Authors: Cook Michael A. , Lopez Jesse J.
Published: April 2023

Gram-negative bacteremia is a common cause of infection in hospitalized patients. Serratia sepsis is known to cause clinically significant morbidity and mortality. The most common species involved is Serratia marcescens. Clinicians have been uncertain as to the role of Serratia odorifera biogroup 1 as a human pathogen because most isolates have not been associated with invasive disease. In previous publications, 12 cases have been described in which S odorifera biogroup 1 caused sepsis. These observations verify the organism’s role as a human pathogen.
Rare presentation of acute urinary retention secondary to herpes zoster
Authors: Ginsberg Phillip C. , Harkaway Richard C. , Elisco III Anthony J. , Rosenthal Brian D. , Renoir Eugene Jean , Gashti Mojtaba , Curras Ernesto B. , Schwartz Kenneth , Edwards Joseph
Published: April 2023

There are many causes of acute urinary retention. Reported here is a case of one of the more rare causes: herpes zoster. Fewer than 70 cases have been reported in the literature since 1890. In the present clinical environment where many patients are immunocompromised, reports of herpes zoster and its sequelae are no longer thought of as anecdotal. The virus may interrupt the detrusor reflex due to involvement of the sacral dorsal root ganglia. Urinary retention with sensory loss of both bladder and rectum as well as flaccid paralysis of the detrusor can develop in patients with herpes zoster. Fortunately, the outcome of this process is benign and full recovery of the detrusor is likely.
Natural history of false-negative Papanicolaou smears: A prospective study using screening colposcopy in addition to cytology
Authors: Robert Mannino J.
Published: April 2023

The regular Papanicolaou (Pap) smear is a cornerstone of women’s preventive healthcare. The introduction of the regular Pap smear as a screening tool for cervical cancer has markedly decreased the number of deaths from cervical cancer. During the past decade, however, the rate of death from cervical cancer has remained relatively static. This screening method is known to have a high rate of false-negative results; therefore, serial examinations are necessary for optimal sensitivity. The sensitivity of the routine pelvic examination is further increased with the addition of colposcopy to cytologic screening.

Patients identified as having disease by colposcopy and biopsy but not by Pap smear (false-negative), are followed up, and the progression of their disease is documented until the Pap smear reflects the known change. A total of 276 patients whose Pap tests showed “no abnormal cells” and mild dysplasia (CIN-1 [cervical intraepithelial neoplasia]) by colposcopy and biopsy, who opted not to be treated, were followed up as a function of time. The results of the Pap test on the 276 patients progressed to a low-grade squamous intraepithelial lesion (LGSIL) or higher within 42 months.

In this study, false-negative Pap tests that were identified by simultaneously performed colposcopy became positive within 42 months; therefore, careful repetitive screening is necessary. The author argues that a definitive, prospective study on the addition of colposcopy or similar adjunct procedure to the routine pelvic examination, in selected cases, is needed.
Olanzapine-induced mania
Authors: Reeves Roy R. , McBride William A. , Brannon Guy E.
Published: April 2023

Olanzapine is a relatively new antipsychotic agent which appears to be effective in the treatment of both the positive and negative symptoms of schizophrenia. Reported here is the case of a patient who developed symptoms of mania secondary to treatment with olanzapine. Physicians prescribing olanzapine should be aware of this potential complication.
Fortuitous diagnosis of iliac osteomyelitis: Septic arthritis of the hip in the neonate
Authors: Duffy Thomas N. , Kruse Richard W. , Massood Stephen M. , Wong Jason
Published: April 2023

The neonate is unable to relate specific complaints of pain and may not exhibit the usual signs of illness or infection. Septic arthritis of the hip is a surgical emergency in the neonate, and it should be considered in any irritable or ill child who has a high index of suspicion. Prompt diagnosis and immediate treatment are necessary. Nearly all babies undergo routine examination of the hip for dysplasia. It is recognized that limitation of abduction of the hip in the neonate may not represent developmental dysplasia of the hip but may represent other etiologies, such as fracture, infection, congenital anomaly, or tumor. The following case report illustrates the importance of careful clinical evaluation of an apparent asymptomatic neonate.
Thyroid hypokalemic periodic paralysis
Authors: Eugene Nida Maurice , Kanj Hassan
Published: April 2023

An unusual presentation of thyrotoxicosis resulting in hypokalemic periodic paralysis is reported here. The patients with this disorder have very low serum potassium levels during the active phase of the disease. Very often, several months pass before the diagnosis is made. Once recognized and the thyrotoxicosis is treated, the patient does well.
A clinician's guide to a woman's heart
Authors: Spratt Kelly Anne
Published: April 2023

Contrary to the perception of most women that breast cancer is the leading cause of death in women, it is heart disease and stroke that claim the most lives of women older than 35 years in the United States. The prevalence of cardiovascular disease is likely to increase as more women—notably the “baby boomers”— enter the menopausal period, a time of increased cardiac vulnerability. Primary care physicians should be on the forefront in taking an inventory of risk factors in their female patients and in educating them about the reality of heart disease in their gender and about the risk factors that these patients can modify to decrease their risk. To aid in their efforts, this article provides an overview of those risk factors that are modifiable, such as weight reduction, exercise, and smoking cessation. It also offers an evaluation of the benefit and nonbenefit of vitamin and herbal supplements in reduction of cardiac events.
Nongynecologic healthcare screening in women
Authors: Krueger Paul M.
Published: April 2023

The primary care physician is bombarded with recommendations regarding health screening and preventive services. Often, these recommendations and guidelines are in conflict. This article will not settle these debates; however, it will provide an overview of recommendations for screening in nongynecologic areas and a framework on how to evaluate conflicting recommendations to give reasonable guidance to patients.
Inverse design in quantum nanophotonics: combining local-density-of-states and deep learning
Authors: Liu Guang-Xin , Liu Jing-Feng , Zhou Wen-Jie , Li Ling-Yan , You Chun-Lian , Qiu Cheng-Wei , Wu Lin
Published: April 2023

Recent advances in inverse-design approaches for discovering optical structures based on desired functional characteristics have reshaped the landscape of nanophotonic structures, where most studies have focused on how light interacts with nanophotonic structures only. When quantum emitters (QEs), such as atoms, molecules, and quantum dots, are introduced to couple to the nanophotonic structures, the light–matter interactions become much more complicated, forming a rapidly developing field – quantum nanophotonics. Typical quantum functional characteristics depend on the intrinsic properties of the QE and its electromagnetic environment created by the nanophotonic structures, commonly represented by a scalar quantity, local-density-of-states (LDOS). In this work, we introduce a generalized inverse-design framework in quantum nanophotonics by taking LDOS as the bridge to connect the nanophotonic structures and the quantum functional characteristics. We take a simple system consisting of QEs sitting on a single multilayer shell–metal–nanoparticle (SMNP) as an example, apply fully-connected neural networks to model the LDOS of SMNP, inversely design and optimize the geometry of the SMNP based on LDOS, and realize desirable quantum characteristics in two quantum nanophotonic problems: spontaneous emission and entanglement. Our work introduces deep learning to the quantum optics domain for advancing quantum device designs; and provides a new platform for practicing deep learning to design nanophotonic structures for complex problems without a direct link between structures and functional characteristics.
Cilia and electroosmosis induced double diffusive transport of hybrid nanofluids through microchannel and entropy analysis
Authors: Munawar Sufian , Saleem Najma , Tripathi Dharmendra
Published: April 2023

A mathematical model is presented to analyze the double diffusive transport of hybrid nanofluids in microchannel. The hybrid nanofluids flow is driven by the cilia beating and electroosmosis in the presence of radiation effects and activation energy. Cu–CuO/blood hybrid nanofluids are considered for this analysis. Phase difference in the beatings of mimetic cilia arrays emerge symmetry breaking pump walls to control the fluid stream. Analytical solutions for the governing equations are derived under the assumptions of Debye–Hückel linearization, lubrication, and Rosseland approximation. Dimensional analysis has also been considered for applying the suitable approximations. Entropy analysis is also performed to examine the heat transfer irreversibility and Bejan number. Moreover, trapping phenomena are discussed based on the contour plots of the stream function. From the results, it is noted that an escalation in fluid velocity occurs with the rise in slippage effects near the wall surface. Entropy inside the pump can be eased with the provision of activation energy input or by the consideration of the radiated fluid in the presence of electroosmosis. The results of the present study can be applicable to develop the emerging thermofluidic systems which can further be utilized for the heat and mass transfer at micro level.
Evaluation of the properties and applications of FRP bars and anchors: A review
Authors: Ren Yuhang , Wang Hongguang , Guan Zhongzhi , Yang Kainan
Published: April 2023

The performance deterioration of steel anchors caused by steel corrosion is becoming more serious in slope anchorage applications. Therefore, the fiber reinforced plastic (FRP) composites have become a substitute material for traditional anchorage structures due to their advantages of low price, lightweight, high strength, and corrosion resistance. Numerous studies have proven that FRP anchors have better anchoring capacity than traditional steel anchors in practical engineering and are not as susceptible to environmental influences. This review mainly introduced the mechanical properties of FRP, focuses on the current research progress and innovation of FRP anchor in anchorage engineering, then provides a basis for the design of FRP anchor. In this study, the failure characteristics and problem of insufficient bonding strength of the first interface of FRP anchor anchoring slope were discussed, and the improvement was introduced. It will be conducive to the extension and application of FRP composites as structural materials in civil engineering. A detailed introduction is also given to biomaterials, which are mainly derived from nature and which will not only reduce waste disposal problems and environmental pollution but will also replace conventional applications. Finally, there will be an important reference and value for the development of green and sustainable engineering structures.
Associations between serum clusterin levels and non-alcoholic fatty liver disease
Authors: Wang Yansu , Shen Yun , Hu Tingting , Wang Yufei , Ma Xiaojing , Yu Haoyong , Bao Yuqian
Published: April 2023

Objective

Clusterin is closely correlated with insulin resistance and its associated comorbidities. This study aimed to investigate the correlation between serum clusterin levels and non-alcoholic fatty liver disease (NAFLD) and further explore the mediating role of insulin resistance in this relationship.

Methods

This study enrolled 195 inpatients (41 males and 154 females) aged 18–61 years. Twenty-four patients were followed up for 12 months after bariatric surgery. Serum clusterin levels were measured using a sandwich enzyme-linked immunosorbent assay. Fatty liver disease was diagnosed on the basis of liver ultrasonography. The fatty liver index (FLI) was calculated to quantify the degree of hepatic steatosis. The mediating role of homeostasis model assessment-insulin resistance (HOMA-IR) was assessed using mediation analysis.

Results

Participants with NAFLD had significantly higher serum clusterin levels than those without NAFLD (444.61 (325.76–611.52) mg/L vs 294.10 (255.20–373.55) mg/L, P < 0.01). With increasing tertiles of serum clusterin levels, the prevalence of NAFLD displayed an upward trend (P < 0.01). Multivariate linear regression analysis showed that serum clusterin levels were a positive determinant of FLI (standardized β = 0.271, P < 0.001) after adjusting for multiple metabolic risk factors. Serum clusterin levels significantly decreased after bariatric surgery (298.77 (262.56–358.10) mg/L vs 520.55 (354.94–750.21) mg/L, P < 0.01). In the mediation analysis, HOMA-IR played a mediating role in the correlation between serum clusterin levels and FLI; the estimated percentage of the total effect was 17.3%.

Conclusion

Serum clusterin levels were associated with NAFLD. In addition, insulin resistance partially mediated the relationship between serum clusterin levels and FLI.