bluuebunny/crossref_metadata_2025 huggingface dataset:
Gangraena i remedium, o herezjach i zwyrodnieniu religijnym w Anglii połowy XVII w.
Authors: Basista Jakub
Published: October 2021

Gangraena and its cure: on Heresies and Religious Perversions in mid-seventeenth century England The English Civil War saw an explosion in the production of printed material. Booklets, pamphlets, leaflets, and ballads of all types and covering all manner of subjects appeared in their thousands. Indeed, the number of titles printed during this period surpassed 2,000 per year. Among these we find a large category of prints denouncing religious heresy and perverse behaviors. The most elaborate of these was Thomas Edwards’s Gangraena, which ran to several thousand pages in length and spanned three consecutive volumes. In this article, the author looks at various religious sects in England and aspects of their beliefs and behaviors to examine how the Restoration England of Charles II tried to cure its population of unorthodox and perverse religious ideas.
Augmented Lagrangian–Based First-Order Methods for Convex-Constrained Programs with Weakly Convex Objective
Authors: Li Zichong , Xu Yangyang
Published: October 2021

First-order methods (FOMs) have been widely used for solving large-scale problems. A majority of existing works focus on problems without constraint or with simple constraints. Several recent works have studied FOMs for problems with complicated functional constraints. In this paper, we design a novel augmented Lagrangian (AL)–based FOM for solving problems with nonconvex objective and convex constraint functions. The new method follows the framework of the proximal point (PP) method. On approximately solving PP subproblems, it mixes the usage of the inexact AL method (iALM) and the quadratic penalty method, whereas the latter is always fed with estimated multipliers by the iALM. The proposed method achieves the best-known complexity result to produce a near Karush–Kuhn–Tucker (KKT) point. Theoretically, the hybrid method has a lower iteration-complexity requirement than its counterpart that only uses iALM to solve PP subproblems; numerically, it can perform significantly better than a pure-penalty-based method. Numerical experiments are conducted on nonconvex linearly constrained quadratic programs. The numerical results demonstrate the efficiency of the proposed methods over existing ones.
A Discrete Convex Min-Max Formula for Box-TDI Polyhedra
Authors: Frank András , Murota Kazuo
Published: October 2021

A min-max formula is proved for the minimum of an integer-valued separable discrete convex function in which the minimum is taken over the set of integral elements of a box total dual integral polyhedron. One variant of the theorem uses the notion of conjugate function (a fundamental concept in nonlinear optimization), but we also provide another version that avoids conjugates, and its spirit is conceptually closer to the standard form of classic min-max theorems in combinatorial optimization. The presented framework provides a unified background for separable convex minimization over the set of integral elements of the intersection of two integral base-polyhedra, submodular flows, L-convex sets, and polyhedra defined by totally unimodular matrices. As an unexpected application, we show how a wide class of inverse combinatorial optimization problems can be covered by this new framework.
Rifampicin-Induced Nephrotoxicity in a Tuberculosis Patient: Treatment Dilemma?
Authors: Grilo Novais Antonio , Silva Cláudio , Coelho Ana Rita , Silva Roberto , Carvalho Ana Cláudia
Published: October 2021

Acute kidney injury related to rifampin is usually a clinical diagnosis. We report a case of a man being treated for pulmonary tuberculosis with acute tubulointerstitial nephritis related to rifampicin.
Skin Rash and Interstitial Pneumonia Can Be a Fatal Combination: A Rare Case of Anti-Melanoma Differentiation-Associated Gene 5 (MDA5)-Associated Interstitial Lung Disease
Authors: Borio Giorgia , Terracciano Chiara , Buttafava Federico , Vercelli Andrea , Pagani Laura , Zanzani Chiara , Manicardi Alessandra , Magnacavallo Andrea , Poggiali Erika
Published: October 2021

We report the case of a 62-year-old male patient fully vaccinated for COVID-19, admitted to our emergency room for persistent fever associated with exertional dyspnoea, skin lesions, diffuse myalgias and arthralgias not responsive to broad-spectrum antibiotic and antiviral therapy, who developed a rapidly progressive refractory to treatment interstitial lung disease due to anti-melanoma differentiation-associated gene 5 (MDA5) antibodies, that required mechanical ventilation and ECMO. Here, we highlight the importance of always considering alternative diagnoses, i.e. viral and autoimmune diseases, including anti-MDA5 antibody screening, when dealing with patients with a skin rash, seronegative polyarthralgias and interstitial pneumonia, or acute respiratory distress syndrome of unknown origin.
Blazed grating pupil remapping and rotational synthesis with computational phase correction for a two-aperture system
Authors: Krug Sarah E. , Rabb David J.
Published: October 2021

Multi-aperture imaging systems can be used to decrease the size,
weight, and cost of an imaging system while retaining a resolution
related to the diameter of the aperture gain. One solution for phasing
apertures in an array uses anamorphic pupil remapping and a
computational phase correction algorithm. It is shown that using
blazed gratings to remap the aperture fields reduces field dependent
contrast and leads to piston corrections for partially coherent
illumination. Additionally, rotational aperture synthesis is used to
combine two piston corrected images and create an image with
resolution increases in more than just the axis of aperture gain.
Fingerprint detection in the mid-infrared region based on guided-mode resonance and phonon-polariton coupling of analyte
Authors: Chen Yu-Shan , Meng Dan , Ma Wen-Zhuang , Chen Wei , Zhuang Ping-Ping , Chen Wen , Fan Zhi-Chun , Dou Chao , Gu Yu , Liu Jing
Published: October 2021

Mid-infrared absorption spectroscopy is an effective method for detecting analyte fingerprints without labeling, but the inherent loss of metals in current methods is a main issue. Here, a sensing scheme was proposed that uses an all-dielectric grating metasurface and angular scanning of polarized light, and then it was verified by numerical simulation. The proposed fingerprint detection scheme could effectively couple a guided-mode resonance spectrum peak with the characteristic peak of the analyte’s phonon-polariton in the mid-infrared region, significantly enhancing the interaction between light and the analyte. The novel scheme would realize broadband enhancement to detect a variety of substances, and facilitate mid-infrared sensing and analysis of trace substances.
Mid-wave/long-wave dual-color infrared quantum cascade detector enhanced by antenna-coupled microcavity
Authors: Zhu Yixuan , Zhai Shenqiang , Liu Junqi , Li Kun , Yang Ke , Liu Shuman , Zhang Jinchuan , Zhuo Ning , Wang Lijun , Liu Fengqi
Published: October 2021

We have demonstrated a mid-wave/long-wave dual-color infrared quantum cascade detector enhanced by antenna-coupled microcavity. By optimizing the size of patches, the coupling wavelength of the antenna-coupled microcavity can be conveniently tuned to match the targeted intersubband transition energy. At 77 K, the peak responsivity of our detector is 4.1 mA/W for long wave (10.4 µm) and 0.6 mA/W for mid wave (5.8 µm), while the detectivity is 1.8×109 cm·Hz1/2/W (Jones) and 2.6×108 cm·Hz1/2/W (Jones), respectively. Compared with a reference device with a 45° multi-pass geometry, the responsivity of our detector has been increased by a factor of 9.1 for the long wave and 2.7 for the mid wave. Our results illustrate how to realize a dual-color infrared detector and improve the optoelectronic performance through the concept of antenna-coupled microcavity.
Extended aberration analysis in symmetry-free optical systems – part I: method of calculation
Authors: Tang Ziyao , Gross Herbert
Published: October 2021

The imaging performance evaluation of symmetry-free optical systems is of great importance during the correction process of optical design. However, due to the complexity and limitations of the available tools, the higher-order aberrations in the system cannot be well analyzed and are hard to control. In this paper, the theoretical background and the mathematical approach of a quantitative analysis method for surface-decomposed transverse aberration in the symmetry-free systems are introduced. With the mixed ray-tracing calculation in both real and paraxial cases, the implementations of full-order intrinsic/induced aberration, as well as the surface-additive Zernike coefficient fitting method are demonstrated. The applications of this method help assess the correction performance considering the relatively critical surfaces in an arbitrary off-axis system. The reliability and the accuracy of the method will be evaluated in part II with a test system. And as an illustration of the practical usage of the method for optical design, the corresponding applications on a group of lithographic systems will also be demonstrated.
Carrier-envelope offset frequency dynamics of a 10-GHz modelocked laser based on cascaded quadratic nonlinearities
Authors: Krüger L. M. , Camenzind S. L. , Phillips C. R. , Keller U.
Published: October 2021

Cascaded quadratic nonlinearities from phase-mismatched second-harmonic generation build the foundation for robust soliton modelocking in straight-cavity laser configurations by providing a tunable and self-defocusing nonlinearity. The frequency dependence of the loss-related part of the corresponding nonlinear response function causes a power-dependent self-frequency shift (SFS). In this paper, we develop a simple analytical model for the SFS-induced changes on the carrier-envelope offset frequency (fCEO) and experimentally investigate the static and dynamic fCEO dependence on pump power. We find good agreement with the measured dependence of fCEO on laser output power, showing a broad fCEO tuning capability from zero up to the pulse repetition rate. Moreover, we stabilize the relative intensity noise to the −157 dBc/Hz level leading to a tenfold reduction in fCEO-linewidth.
Spatial-light-modulator-based optical-fiber joint switch for few-mode multicore fibers
Authors: Zhang Shuanglu , Okamoto Atsushi , Abe Yuta , Watanabe Ryo , Tomita Akihisa , Soma Daiki , Wakayama Yuta , Tsuritani Takehiro
Published: October 2021

To realize simplified cost-efficient optical networks with routing flexibility and scaling potential, a spatial-light-modulator-based optical-fiber joint switch for few-mode multicore fibers is proposed herein, which can route all spatial channels together as a unit. Numerical simulations and experiments were performed, and the results show that the signal paths for a 6-mode 19-core fiber can be simultaneously switched to the target output ports using the proposed method, and the mode-field patterns of the diffracted light can be maintained after joint switching. Further, the maximum port crosstalk can be reduced considerably from -11.6 to -25.1 dB by changing the position of the output port in the proposed method.
Incoherent two-color pulse compounds
Authors: Melchert O. , Demircan A.
Published: October 2021

We study the dynamical evolution of two-frequency pulse compounds, i.e., intriguing bound-states of light, kept together due to their incoherent interaction. A special class of solutions of such compounds is found to be describable in terms of a simplified model. They entail generalized dispersion Kerr solitons and yield their corresponding metasolitons. We use these solutions to study when the interaction of their constituent pulses is independent of their phase. These results are relevant to understand the complex collision dynamics of quasi-group-velocity-matched solitons across a vast frequency gap.
Geometric optimization method for a polarization state generator of a Mueller matrix microscope
Authors: Zhao Qianhao , Huang Tongyu , Hu Zheng , Bu Tongjun , Liu Shugang , Liao Ran , Ma Hui
Published: October 2021

We propose a geometric optimization method combined with the Coulombic energy indicator that can uniformly distribute

N

polarization states on the Poincaré sphere. Based on this method, we investigate the optimal frames of a rotating polarizer and rotating quarter-wave plate (RPRQ)-based polarization state generator (PSG) at different numbers of modulations. We use the PSG on a dual DoFP polarimeter-based Mueller matrix microscope to measure standard samples and pathological sections for testing the performance of an optimized RPRQ. The experimental results show that this method can effectively restrain noise and improve measurement accuracy.
Computational vector fiducial for deflectometry system alignment
Authors: Kang Hyukmo , Quach Henry , Berkson Joel , Aftab Maham , Smith George , Choi Heejoo , Kim Daewook
Published: October 2021

One of deflectometry’s cardinal strengths is its ability to measure highly dynamically sloped optics without needing physical null references. Accurate surface measurements using deflectometry, however, require precise calibration processes. In this Letter, we introduce an alignment technique using a computational fiducial to align a deflectometry system without additional hardware equipment (i.e., algorithmic innovation). Using the ray tracing program, we build relationships between the plane of the screen and detector and algorithmically generate a fiducial pattern for the deflectometry configuration. Since the fiducial pattern is based on ideal system geometry, misalignment of the unit under test with its target position causes a discrepancy between the actual image on the camera detector and the ideal fiducial image. We leverage

G

and

C

vector polynomials to quantify misalignment and estimate the alignment status through a reverse optimization method. Simulation and experimental results demonstrate that the proposed algorithm can align the

195

m
m

×
80

m
m

of a rectangular aperture freeform optic within 10 µm of peak-to-valley accuracy. The computational fiducial-based alignment algorithm is simple to apply and can be an essential procedure for conventional methods of deflectometry system alignment.
Metallic nanosphere-assisted coupling ultrafast surface plasmon polaritons background-free tip nanofocusing
Authors: Meng Chao , Li Weijian , Xie Zhonglin , Zhang Lu , Xu Lei , Gao Feng , Zhang Wending , Mei Ting , Zhao Jianlin
Published: October 2021

Plasmonic tip nanofocusing has gained much attention owing to its wide application in the field of nanospectroscopy. Here, we present the Au nanosphere (AuNS)-assisted coupling ultrafast surface plasmon polaritons (SPP) background-free tip nanofocusing. The plasmonic tip was prepared by attaching an AuNS on the shaft of an Au conical tip fabricated by electrochemical etching. The AuNS was adopted as an antenna to couple the far-field excitation light to the propagating SPP along the shaft to the tip apex for achieving power compression. Importantly, we experimentally and theoretically demonstrate that such a plasmonic tip can realize background-free ultrafast SPP tip nanofocusing with radially polarized features in a wide spectral range based on the localized SPP resonance effect supported by AuNS. Furthermore, the intensity of the tip nanofocusing light field has strong polarization dependence under linearly polarized light excitation, providing a powerful platform for spatiotemporal light control on the nanoscale. Our technique realizes remote excitation of background-free tip nanofocusing with a structured light feature, and it holds promising potential for tip-enhanced nanospectroscopies, nonlinear nanophotonics, etc.
Low loss hybrid plasmon polariton Mach-Zehnder modulators
Authors: Xing JiangHao , Sun Changzheng , Xiong Bing , Wang Jian , Hao Zhibiao , Wang Lai , Han Yanjun , Li HongTao , Yu Jiadong , Luo Yi
Published: October 2021

We propose a hybrid plasmon polariton (HPP) Mach-Zehnder modulator (MZM) structure that combines the tight optical confinement of plasmonic waveguides and narrow slot waveguides with the low loss feature of photonic waveguides. Compared with conventional surface plasmon polariton (SPP) modulators, the HPP modulator exhibits lower propagation loss and better overall performance. Simulations based on the finite difference time-domain (FDTD) and finite element method (FEM) predict a half-wave voltage-length product of 0.078 V·mm for the HPP modulator. Meanwhile, the propagation loss is only 0.2 dB/μm, which is less than half of that for an SPP modulator. The modulation bandwidth of a 10-μm-long HHP modulator exceeds 650 GHz, while the total insertion loss of the device is estimated to be lower than 4 dB.
Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma
Authors: Weaver Davis T. , Pishas Kathleen I. , Williamson Drew , Scarborough Jessica , Lessnick Stephen L. , Dhawan Andrew , Scott Jacob G.
Published: October 2021

MicroRNA (miRNA)-based therapies are an emerging class of targeted therapeutics with many potential applications. Ewing Sarcoma patients could benefit dramatically from personalized miRNA therapy due to inter-patient heterogeneity and a lack of druggable (to this point) targets. However, because of the broad effects miRNAs may have on different cells and tissues, trials of miRNA therapies have struggled due to severe toxicity and unanticipated immune response. In order to overcome this hurdle, a network science-based approach is well-equipped to evaluate and identify miRNA candidates and combinations of candidates for the repression of key oncogenic targets while avoiding repression of essential housekeeping genes. We first characterized 6 Ewing sarcoma cell lines using mRNA sequencing. We then estimated a measure of tumor state, which we term network potential, based on both the mRNA gene expression and the underlying protein-protein interaction network in the tumor. Next, we ranked mRNA targets based on their contribution to network potential. We then identified miRNAs and combinations of miRNAs that preferentially act to repress mRNA targets with the greatest influence on network potential. Our analysis identified TRIM25, APP, ELAV1, RNF4, and HNRNPL as ideal mRNA targets for Ewing sarcoma therapy. Using predicted miRNA-mRNA target mappings, we identified miR-3613-3p, let-7a-3p, miR-300, miR-424-5p, and let-7b-3p as candidate optimal miRNAs for preferential repression of these targets. Ultimately, our work, as exemplified in the case of Ewing sarcoma, describes a novel pipeline by which personalized miRNA cocktails can be designed to maximally perturb gene networks contributing to cancer progression.
Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes
Authors: Rutkowski David M. , Vavylonis Dimitrios
Published: October 2021

Mechanical forces, actin filament turnover, and adhesion to the extracellular environment regulate lamellipodial protrusions. Computational and mathematical models at the continuum level have been used to investigate the molecular clutch mechanism, calculating the stress profile through the lamellipodium and around focal adhesions. However, the forces and deformations of individual actin filaments have not been considered while interactions between actin networks and actin bundles is not easily accounted with such methods. We develop a filament-level model of a lamellipodial actin network undergoing retrograde flow using 3D Brownian dynamics. Retrograde flow is promoted in simulations by pushing forces from the leading edge (due to actin polymerization), pulling forces (due to molecular motors), and opposed by viscous drag in cytoplasm and focal adhesions. Simulated networks have densities similar to measurements in prior electron micrographs. Connectivity between individual actin segments is maintained by permanent and dynamic crosslinkers. Remodeling of the network occurs via the addition of single actin filaments near the leading edge and via filament bond severing. We investigated how several parameters affect the stress distribution, network deformation and retrograde flow speed. The model captures the decrease in retrograde flow upon increase of focal adhesion strength. The stress profile changes from compression to extension across the leading edge, with regions of filament bending around focal adhesions. The model reproduces the observed reduction in retrograde flow speed upon exposure to cytochalasin D, which halts actin polymerization. Changes in crosslinker concentration and dynamics, as well as in the orientation pattern of newly added filaments demonstrate the model’s ability to generate bundles of filaments perpendicular (actin arcs) or parallel (microspikes) to the protruding direction.
Impacts of multicollinearity on CAPT modalities: An heterogeneous machine learning framework for computer-assisted French phoneme pronunciation training
Authors: Bi Yanjing , Li Chao , Benezeth Yannick , Yang Fan
Published: October 2021

Phoneme pronunciations are usually considered as basic skills for learning a foreign language. Practicing the pronunciations in a computer-assisted way is helpful in a self-directed or long-distance learning environment. Recent researches indicate that machine learning is a promising method to build high-performance computer-assisted pronunciation training modalities. Many data-driven classifying models, such as support vector machines, back-propagation networks, deep neural networks and convolutional neural networks, are increasingly widely used for it. Yet, the acoustic waveforms of phoneme are essentially modulated from the base vibrations of vocal cords, and this fact somehow makes the predictors collinear, distorting the classifying models. A commonly-used solution to address this issue is to suppressing the collinearity of predictors via partial least square regressing algorithm. It allows to obtain high-quality predictor weighting results via predictor relationship analysis. However, as a linear regressor, the classifiers of this type possess very simple topology structures, constraining the universality of the regressors. For this issue, this paper presents an heterogeneous phoneme recognition framework which can further benefit the phoneme pronunciation diagnostic tasks by combining the partial least square with support vector machines. A French phoneme data set containing 4830 samples is established for the evaluation experiments. The experiments of this paper demonstrates that the new method improves the accuracy performance of the phoneme classifiers by 0.21 − 8.47% comparing to state-of-the-arts with different data training data density.
Qualitative lysine crotonylome analysis in the ovarian tissue of Harmonia axyridis (Pallas)
Authors: Zheng Changying , Sun Lijuan
Published: October 2021

Lysine crotonylation (Kcr) is a newly discovered posttranslational modification (PTM), which has been studied at the proteomics level in a few species, with the study of Kcr in female fertility and in insect species is still lacking.Harmonia axyridis(Pallas) is a well-known beneficial insect used as a natural biological control agent against aphids in agriculture. Here, global Kcr identification in ovarian tissue ofH.axyridisat diapause stage was performed to reveal potential roles for Kcr inH.axyridisovarian cellular processes, female fertility and diapause regulation. In total, 3084 Kcr sites in 920 proteins were identified. Bioinformatic analyses revealed the distribution of these proteins in multiple subcellular localization categories and their involvement in diverse biological processes and metabolism pathways. Carbohydrate and energy metabolism related cellular processes including citric acid cycle, glycolysis and oxidative phosphorylation appeared be affected by Kcr modification. In addition, regulation of translation and protein biosynthesis may reflect Kcr involvement in diapause inH.axyridis, with Kcr affecting ribosome activities and amino acid metabolism. Moreover, Kcr modulationH.axyridisovary development regulation may share some common mechanism with Kcr participation in some disease progression. These processes and pathways were uncovered under diapause stage, but possibly not enriched/specific for diapause stage due to limitations of qualitative proteomics experimental design. Our results informs on the potential for Kcr modifications to regulate female fertility and insect physiology.
A new framework based on features modeling and ensemble learning to predict query performance
Authors: Zaghloul Mohamed , Salem Mofreh , Ali-Eldin Amr
Published: October 2021

A query optimizer attempts to predict a performance metric based on the amount of time elapsed. Theoretically, this would necessitate the creation of a significant overhead on the core engine to provide the necessary query optimizing statistics. Machine learning is increasingly being used to improve query performance by incorporating regression models. To predict the response time for a query, most query performance approaches rely on DBMS optimizing statistics and the cost estimation of each operator in the query execution plan, which also focuses on resource utilization (CPU, I/O). Modeling query features is thus a critical step in developing a robust query performance prediction model. In this paper, we propose a new framework based on query feature modeling and ensemble learning to predict query performance and use this framework as a query performance predictor simulator to optimize the query features that influence query performance. In query feature modeling, we propose five dimensions used to model query features. The query features dimensions are syntax, hardware, software, data architecture, and historical performance logs. These features will be based on developing training datasets for the performance prediction model that employs the ensemble learning model. As a result, ensemble learning leverages the query performance prediction problem to deal with missing values. Handling overfitting via regularization. The section on experimental work will go over how to use the proposed framework in experimental work. The training dataset in this paper is made up of performance data logs from various real-world environments. The outcomes were compared to show the difference between the actual and expected performance of the proposed prediction model. Empirical work shows the effectiveness of the proposed approach compared to related work.
Prediction of municipality-level winter wheat yield based on meteorological data using machine learning in Hokkaido, Japan
Authors: Murakami Keach , Shimoda Seiji , Kominami Yasuhiro , Nemoto Manabu , Inoue Satoshi
Published: October 2021

This study analyzed meteorological constraints on winter wheat yield in the northern Japanese island, Hokkaido, and developed a machine learning model to predict municipality-level yields from meteorological data. Compared to most wheat producing areas, this island is characterized by wet climate owing to greater annual precipitation and abundant snowmelt water supply in spring. Based on yield statistics collected from 119 municipalities for 14 years (N = 1,516) and high-resolution surface meteorological data, correlation analyses showed that precipitation, daily minimum air temperature, and irradiance during the grain-filling period had significant effects on the yield throughout the island while the effect of snow depth in early winter and spring was dependent on sites. Using 10-d mean meteorological data within a certain period between seeding and harvest as predictor variables and one-year-leave-out cross-validation procedure, performance of machine learning models based on neural network (NN), random forest (RF), support vector machine regression (SVR), partial least squares regression (PLS), and cubist regression (CB) were compared to a multiple linear regression model (MLR) and a null model that returns an average yield of the municipality. The root mean square errors of PLS, SVR, and RF were 872, 982, and 1,024 kg ha−1 and were smaller than those of MLR (1,068 kg ha−1) and null model (1,035 kg ha−1). These models outperformed the controls in other metrics including Pearson’s correlation coefficient and Nash-Sutcliffe efficiency. Variable importance analysis on PLS indicated that minimum air temperature and precipitation during the grain-filling period had major roles in the prediction and excluding predictors in this period (i.e. yield forecast with a longer lead-time) decreased forecast performance of the models. These results were consistent with our understanding of meteorological impacts on wheat yield, suggesting usefulness of explainable machine learning in meteorological crop yield prediction under wet climate.
¿Madre bondadosa o cruel madrastra? Imagen nacional y caricaturas en la cultura visual de Cuba (1868-1878)
Authors: Gilarranz Ainhoa
Published: October 2021

A lo largo del siglo XIX, las mejoras técnicas en el mundo de la imprenta permitieron introducir asiduamente grabados, ilustraciones y caricaturas entre sus publicaciones. Los dibujantes satíricos se hacían eco de los acontecimientos que se debatían entre la sociedad y los representaban mediante su código humorístico en las páginas de prensa. La personificación de las naciones en alegorías, principalmente femeninas, se popularizó entre los caricaturistas proyectando imaginarios nacionales con unas características muy concretas. En los momentos de mayor conflicto social y político estas representaciones nacionales brotaban difundiendo ideales, opiniones y corrientes de pensamiento que llegaban a la población. Uno de esos acontecimientos fue la Guerra de los diez años (1868-1878) entre Cuba y España, el primero de los conflictos por la independencia que enfrentó a la colonia con la metrópolis. Mediante el estudio de fuentes iconográficas, principalmente las ilustraciones de Víctor Patricio de Landaluze en la publicación españolista Juan Palomo, se profundiza en la construcción del imaginario nacional tanto de España como de Cuba durante el conflicto, en el papel de la otredad en la fabricación de estas representaciones y su consolidación en otros productos: literatura y objetos cotidianos, con la intención de analizar la contienda desde su dimensión cultural.
utilização de um livro paradidático como recurso pedagógico no componente curricular Educação Física para pensar a Inclusão escolar e esportiva
Authors: Cavalcante Lima Kênio Erithon , Tabosa Guimarães Matias Keoma , Nunes Ribeiro Ernani
Published: October 2021

A aplicação de livros paradidáticos para contextualizar e disseminar conhecimentos se coloca promissor na Educação Básica. Neste estudo, utilizamos um livro paradidático com a temática prática esportiva do vôlei sentado com inclusão no espaço escolar em que avaliamos a sua aplicabilidade à melhor apropriação de regras e situação de jogo. Procedemos com a leitura e reflexões sobre o livro com escolares do 1ºano médio, seguido de intervenções prática do vôlei adaptado para posterior diagnóstico através de pesquisa na Escala Likert e questões discursivas sobre a pertinência do livro ao processo de aprendizagem sobre a temática em estudo. Os participantes relatam ser significante o processo lúdico com o livro paradidático à aprendizagem de novos conhecimentos dentro de um campo de saberes sobre inclusão escolar e esportiva, temática pouco ou nada discutida à formação social dos estudantes no âmbito escolar. Constata-se descuido no processo de ensino por não trabalhar o tema com a devida seriedade necessária.
Teatro e Educação Inclusiva:
Authors: Ferreira da Silva Carlos Alberto
Published: October 2021

Propõe-se com este texto relatar a experiência do projeto de extensão denominado Teatro e Educação Inclusiva: uma proposta pedagógica no Centro de Ensino Especial Dom Bosco e no Centro de Apoio Pedagógico para Atendimento às Pessoas com Deficiência Visual de Rio Branco, realizado na Universidade Federal do Acre, entre os meses de maio a dezembro de 2020. A pesquisa desenvolvida, de forma remota, contou com a participação de discentes da Universidade Federal do Acre, que atuaram como bolsistas para a realização da prática pedagógica com pessoas com deficiência. Para o desdobramento do projeto, quatro fases foram importantes, sendo elas: I – Formação sobre os temas e encontros com especialistas da área; II – Participação e Organização de eventos relacionados a Teatro e Acessibilidade Cultural; III – Realização de planejamento e preparação das aulas de teatro com alunos e alunas com deficiência; IV – Ministrar aulas para 22 discentes com deficiência do Centro de Apoio Pedagógico ao Deficiente Visual (CAPDV) e do Centro de Ensino Especial Dom Bosco. Portanto, neste texto, propõe-se descrever o percurso e as referências que serviram de base para o desenvolvimento das abordagens teatrais com os referidos discentes.
Trilhas de Aprendizagem, Metodologias Ativas e Ágeis para o Autodesenvolvimento
Authors: CHAGAS ROSANA AUGUSTO CHAGAS , Magalhães Ribeiro Nuno , Dias Costa Thiago
Published: October 2021

Organizações que aprendem relacionam resultados ao crescimento pessoal de seus colaboradores. Assim, muitas são as possibilidades de busca por desenvolvimento por parte das organizações e autodesenvolvimento por parte dos colaboradores. Com esse objetivo foi realizado um estudo comparativo entre trilhas de aprendizagem e metodologias ativas. Para realizar a comparação foram entrevistadas às Universidade Corporativa do Banco do Brasil, a Universidade Corporativa do Sebrae, a Escola de Contas do Distrito Federal e a Escola Nacional de Administração Pública que ofertam capacitação no formato de trilhas de aprendizagem. Os resultados foram comparados às 5 técnicas de metodologias ativas que apontaram como resultado que as duas abordagens são voltadas para quantidade diferentes de colaboradores a desenvolver competências. Além das trilhas de aprendizagem e as metodologias ativas, o conceito de metodologias ágeis emergiu como indicado para o autodesenvolvimento e a capacitação de gestores. Assim, as metodologias ágeis também foram objeto de comparação no estudo.
Gênero Folheto Educativo na Aula de Língua Espanhola
Authors: Almeida Santos Jakelliny , Santos Rosa Acassia dos Anjos
Published: October 2021

A partir do núcleo de língua espanhola do Programa Residência Pedagógica da Universidade Federal de Sergipe foram desenvolvidas aulas no Centro de Excelência Dom Luciano José Cabral Duarte cuja instituição localiza-se em Aracaju/SE. Neste trabalho, há um recorte de dois encontros ministrados, em modalidade remota, com uma turma do 3° ano do ensino médio. Partimos das competências e tecnologias, bem como as habilidades, da Base Nacional Comum Curricular (BRASIL, 2018) e dos postulados da educação intercultural (MENDES, 2010) para fundamentar o estudo do gênero folheto. Para tal, a temática selecionada está vinculada à prevenção do HIV (sigla em inglês para Vírus da Imunodeficiência Adquirida) vírus causador da AIDS (Síndrome da Imunodeficiência Adquirida) e, por meio do estudo do gênero folheto educativo em espanhol, buscamos promover conscientização da prevenção sexual. Os encontros foram realizados nos dias 5 e 10/12/2020 e as/os estudantes foram adolescentes de ambos os sexos na faixa etária entre 15 e 19 anos. Em síntese, as/os estudantes participaram expondo suas dúvidas e compartilhando saberes oriundos de suas subjetividades e do meio social em que estão inseridos. Assim, foi possível estimular debates construtivos acerca da relevância da prevenção sexual bem como elucidar mitos e verdades sobre a AIDS.
Análise e comparação dos aplicativos Duolingo, Babbel e Memrise para aprendizagem de língua inglesa
Authors: Della Rosa Stefanie Fernanda Pistoni , Chagas Danielle
Published: October 2021

O uso da tecnologia está presente em inúmeras atividades cotidianas. Considerando o aprendizado de uma língua estrangeira, verificamos uma variedade de plataformas que possibilitam contato com a língua visando o aprendizado. Entendemos que a aprendizagem de uma língua não se restringe a dominar regras gramaticais ou à memorização de vocabulários, mas conseguir interagir e se comunicar, criando sentidos na língua-alvo. Este trabalho compara e analisa com respaldo em teorias de ensino e aprendizagem de línguas os aplicativos Duolingo, Babbel e Memrise, que se autodenominam plataformas de ensino de língua inglesa, considerando os seguintes aspectos: desenvolvimento das quatro habilidades, explicações gramaticais, exercícios de tradução para língua materna ou língua estrangeira, conteúdo significativo e correção orientada das produções. A escolha dos aplicativos se baseou no número de downloads e na avaliação de usuários e a primeira lição de cada aplicativo foi analisada. Verificamos que todos os aplicativos oportunizam contato com a língua inglesa com base em conteúdos que possibilitam a transposição do que é aprendido para situação real de uso da língua. Todavia, a análise evidencia uma compreensão de língua como código, sem considerar língua como prática social e para comunicação e interação.
Avaliação e formação de professores de línguas
Authors: Damacena Mariana , Quevedo-Camargo Gladys
Published: October 2021

Partindo da premissa de que a avaliação é parte integrante do processo de ensino e aprendizagem de línguas, este artigo apresenta um microestudo que investigou as percepções de alunos-graduandos do curso de licenciatura em Letras-Inglês de uma universidade pública da região Centro-Oeste sobre sua própria formação para avaliar. Para analisar as informações fornecidas pelos participantes, apoiamo-nos nos conceitos basilares de professor reflexivo (SCHON, 1983; 1992; CONTRERAS, 2002) e de letramento em avaliação (de línguas) (STIGGINS, 1991; SCARAMUCCI, 2016; QUEVEDO-CAMARGO; SCARAMUCCI, 2018). A metodologia utilizada incluiu entrevistas semiestruturadas e análise documental (PRODANOV; FREITAS, 2003) do currículo do curso de formação de professores em Letras-Inglês da universidade. As análises das entrevistas indicam que os licenciandos entendem a importância dos conhecimentos pedagógicos para sua formação e, sobretudo, sentem falta de disciplinas que abordem a avaliação de línguas. Concluímos que é necessário que o letramento em avaliação de línguas seja uma das pautas centrais para discussão nos cursos de formação de professores, para que os formandos compreendam o processo avaliativo de maneira integral, desde a formulação dos objetivos e a elaboração de instrumentos até a interpretação dos dados e a tomada de decisões a partir deles, e, assim, exerçam seus papéis de professores-avaliadores reflexivos.
Pathobiochemical pathways of redox imbalance in the neurological long-term effects of COVID-19 and the role of chondroitin sulfate in the redox status restoration
Authors: Sarvilina I. V. , Gromova O. A. , Naumov A. V.
Published: October 2021

The review examines the epidemiology and clinical manifestations of COVID-19 long-term neurological effects, main pathobiochemical mechanisms, and integrated circuits of redox status impairment in COVID-19, such as the decrease of adenosine triphosphate production, fatty acids levels, acylcarnitine, and amino acids, impairment of oxidative phosphorylation and glycolysis, hypometabolic state, redox imbalance with the increase of peroxides and superoxides, isoprostanes, the decrease of α-tocopherol, substances reacting with thiobarbituric acid, increased nitrosative stress with the increase of inducible synthase of nitric oxide, nitric oxide, peroxynitrite, and nitrate. Neuroprotective approaches aimed at suppressing excitotoxicity, oxidative stress, and neuroinflammation are presented. Recent data on the relationship between mechanisms of chondroitin sulfate and its derivatives (chondroitin sulfate glycoprotein disaccharide) neuroprotective effects and characteristics of their chemical structure are analyzed. The mechanism of action and neuroprotective effects of chondroitin sulfate and its derivatives in fatigue syndrome in patients with SARS-CoV2 infection are discussed (regulation of the PKC/PI3K/Akt activity, the increase of heme oxygenase-1 level, the decrease of reactive oxygen species). The position that chondroitin sulfate and its derivatives can become promising drugs to prevent the long-term neurological effects of COVID-19 is reasoned.
Awareness of cardiovascular diseases risk factors, attitude towards their health and sleep disorders among the 25–64 years old population in Russia/Siberia (WHO International «MONICA-psychosocial» program)
Authors: Gafarov V. V. , Gromova E. A. , Panov D. O. , Gagulin I. V. , Tripelhorn A. N. , Gafarova A. V.
Published: October 2021

Objective: to establish associations of awareness and attitude towards cardiovascular diseases (CVDs) prevention in people with sleep disorders in an open population of Novosibirsk aged 25–64 years.

Patients and methods. We carried out screening surveys of representative samples of the 25–64 years old population: in 2013–2016 – V screening (427 men, mean age– 34±0.4 years, response rate – 71%; 548 women, mean age– 35±0.4 years, response rate – 72%); in 2015–2018 – VI screening (275 men, mean age – 49±0.4 years, response rate – 72%; 390 women, mean age – 45±0.4 years, response rate – 75%) using the protocol of the WHO international program «MONICA-psychosocial». Jenkins sleep evaluation questionnaire was used to evaluate sleep disorders in the study population.

Results and discussion. Participants with sleep disorders believed that they were «not entirely healthy» (men – 65.5%, χ2 =57.825, df=8, p<0.001 and women – 69.6%, χ2 =96.883, df=4, p<0.001); had health related complaints (men – 78.2%, χ2 =24.179, df=2, p<0.001 and women – 85.2%, χ2 =55.144, df=2, p<0.001), and clearly did not care enough about their health (men – 32.7%, χ2 =29.31, df=4, p<0.001 and women – 34.1%, χ2 =28.116, df=4, p<0.001). Men with sleep disorders more often assumed that they were more likely to get a serious illness within the next 5–10 years (χ2 =12.976, df=4, p<0.01). Participants with sleep disorders were confident that modern medicine can prevent (men – 10.9%, χ2 =19.079, df=2, p<0.001 and women – 13.3%, χ2 =21.944, df=2, p<0.01) and successfully treat (men – 3.6%, χ2 =24.142, df=8, p<0.01 and women – 3.7%, χ2 =15.538, df=8, p<0.05) only some heart diseases. Men and women with sleep disorders are more likely to seek medical attention in case of severe pain or discomfort in the heart area, but do not seek medical advice if this pain or unpleasant sensation is mild (men – 63.6%, χ2 =14.867, df=6, p<0.05 and women – 60%, χ2 =17.872, df=6, p<0.01). Among the participants with sleep disorders men more often believe that the doctor «knows more than me» (36.4%), and women (48.1%) chose an answer: «I will not necessarily agree with the opinion of the doctor after a general examination, until a thorough evaluation has been carried out by specialists» (χ2 =5.917, df=2, p<0.05). Women with sleep disorders were more likely to continue to work if they did not feel very well (54.1%, χ2 =12.455, df=4, p<0.05) or their body temperature rose (37.8%, χ2 =12.937, df=4, p<0.05).

Conclusion. People with sleep disorders generally have a more negative attitude towards their health and are skeptical about the possibilities of modern medicine to prevent and treat CVDs, which is reflected in their attitude to work and preventive check-ups.
Management of patients with pain syndromes associated with COVID-19
Authors: Akhmedzhanova L. T. , Ostroumova T. M. , Solokha O. A.
Published: October 2021

The disease caused by the SARS-CoV-2 virus is multi-organ and involves almost all organs and systems. Myalgias and arthralgias and, in particular, back pain are common symptoms of COVID-19 and can be observed both at the onset of the disease and in the postcovid period. The causes of muscle and joint damage include both systemic inflammation and direct viral injury. Traditionally, musculoskeletal pain is treated with non-steroidal anti-inflammatory drugs. However, using this drug class in patients with COVID-19 requires caution due to the presence of comorbid diseases and possible complications of viral infection. The review discusses clinical variants and pathophysiological mechanisms of joints and muscles damage in patients with COVID-19 and treatment tactics for patients with musculoskeletal pain.
Mapeamento de resíduos em projeto
Authors: Sousa Nílberte Muniz de , Nascimento Elivelthon Carlos do , Figueiredo Amanda Almeida de Oliveira , Almeida Maria Fernanda de
Published: October 2021

A construção civil é um dos setores que mais produzem resíduos, podendo atingir volumes de geração próximos a 50% em massa dos resíduos sólidos urbanos. No entanto, a sua existência está ligada, muitas vezes a falhas de projeto, sendo necessário, portanto, estudar os pontos críticos para minimizar a sua produção. O presente estudo teve como objetivo a realização de uma pesquisa na cidade do Recife (PE) para avaliar a perspectiva, as atitudes e comportamentos de projetistas com relação as principais causas e origens dos resíduos de construção (RCC) em projetos. Esta pesquisa envolveu uma amostra populacional de 11 projetistas de diferentes empresas, utilizando questionários, a fim de entender o perfil dos profissionais, seus requisitos na concepção dos trabalhos e a relação com as causas que interferem na geração dos resíduos em projeto. Os resultados demonstraram, em geral, que os projetistas não compreendem a influência do projeto na produção de resíduos. Dentre outros, fatores como a incompatibilidade entre projetos, a limitação de tempo e o desinteresse por parte das empresas e clientes foram apontados como causadores. Concluiu-se que faltam políticas de incentivo as quais visem modificar este cenário para reduzir a geração do RCC desde o projeto.
Abordagens territoriais da educação do campo: Uma análise da experiência territorial da Escola Família Agrícola Normília Cunha dos Santos
Authors: Almeida Edineia Sodré Pereira de , Nonato Eunice Maria Nazarethe , Vilarino Maria Terezinha
Published: October 2021

Ao se considerar o território enquanto espaço transformado por meio das relações sociais que se dão em seus limites, o Campo aparece como espaço da territorialidade que é própria dos camponeses. Assim, a construção da Educação do Campo, como experiência educacional do campesinato mediada pela Pedagogia da Alternância, é a expressão de uma territorialidade específica. A questão que conduz o estudo é de que modo essa territorialidade demarca o território camponês. O campo de estudo do presente trabalho foi a Escola Família Agrícola (EFA) Normília Cunha dos Santos, situada no município de Barra de São Francisco-ES. Assim, o objetivo proposto neste estudo é compreender de que modo a EFA mencionada vivencia a Pedagogia da Alternância como territorialidade campesina e o enfrentamento de tensões externas que atingem seu funcionamento. A metodologia adotada é do tipo territorial, qualitativa, utilizando como fontes de pesquisa bibliografia a partir dos estudos da educação do campo, documentos da escola e diário de bordo. Conclui-se que os processos pedagógicos da EFA estudada, por meio da Educação do Campo e da Pedagogia da Alternância, permanecem alinhavados à própria historicidade das lutas camponesas no território.
The New Right: Conservative student political repertoires and intragroup conflict
Authors: Havey Nicholas
Published: October 2021

This qualitative single-site case study explores how students identifying as conservative position themselves within the discursive field of their campus, how they understand their rhetorical and discursive development in relation to their more liberal peers, and what increasing political polarization means for college campuses. I find that the differences within the conservative student group studied are stronger and more concerning than how they describe differing from their liberal peers, particularly as the conservative student group I analyzed radicalized and became overtly racist and nationalistic. This is worrisome, as my participants noted this was not “a local problem” and mentioned that this was happening at a state and national level. This reality was evidenced by the recent insurrection at the Capitol.