bluuebunny/crossref_metadata_2025 huggingface dataset:
The foreign language effects on strategic behavior games
Authors: Wang Zilu , Yip Michael C. W.
Published: November 2022

The present study examined foreign language effects on the decisions made in a series of strategic behavioral games (e.g., the Prisoner’s Dilemma, the Oligopolistic Competition, and the Volunteer’s Dilemma). We recruited 154 native Chinese-speaking university students, with English as their second language, as participants. They were asked to make decisions while playing four simple behavioral games in either Chinese or English language version and to complete a Language History Questionnaire. The results showed that 1) the participants in each language group performed differently in the Prisoner’s Dilemma Game and in one condition of the Volunteer’s Dilemma Game which involved a relatively high level of uncertainty; and 2) foreign language proficiency, frequency of application and cultural identity triggered by the corresponding foreign language moderated the foreign language effects. This pattern of results is consistent with the Cultural Accommodation Hypothesis and the risk-aversion preference to use one’s native language.
Impact of excessive gestational weight gain on exclusive breastfeeding among women with Type 1 and Type 2 diabetes and obesity
Authors: Cordero Leandro , Stenger Michael R. , Landon Mark B. , Nankervis Craig A.
Published: November 2022

Background

Pregestational diabetes, obesity and gestational weight gain (GWG) are associated with adverse perinatal outcomes, however, the influence ofexcessiveGWG on lactation at discharge is less known. Our aim is to evaluate the impact ofexcessiveGWG using the LifeCycle project guidelines on exclusive breastfeeding (EBF) and any BF rates at discharge among 171 women with Type 1 and 294 Type 2 diabetes and obesity who intended to BF.

Methods and findings

Retrospective cohort study. Obesity was defined by BMI (kg/m2) as grade 1 (30–34.9), grade 2 (35–39.9) or grade 3 (≥40). GWG was categorized asadequate,inadequate or excessiveaccording to the 2019 LifeCycle Project guidelines. Women with Type 1 were younger (30 vs 33y), primiparous (51 vs 32%), delivered earlier (37 vs 38w) than women with Type 2 andwere different in grade 1 (40 vs 26%), grade 3 obesity (19 vs 49%) and median GWG (15 vs 11kg). Of all 465 women with Type 1 and Type 2 combined, 365 (78%) who hadexcessiveGWG and 100 (22%) who had non-excessiveGWG showed similar EBF (27 vs 25%) and any BF (72 vs 72%) rates. Regression analysis showed that after adjusting for potential confoundersexcessiveGWG was not a predictor of EBF or any BF at discharge.

Conclusion

Type 1 and Type 2 diabetes, obesity and excessive GWG are associated with low EBF, however,excessiveGWG is not an independent predictor of low EBF or any BF at discharge.
Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array data
Authors: Mizrahi-Man Orna , Woehrmann Marcos H. , Webster Teresa A. , Gollub Jeremy , Bivol Adrian , Keeble Sara M. , Aull Katherine H. , Mittal Anuradha , Roter Alan H. , Wong Brant A. , Schmidt Jeanette P.
Published: November 2022

The UK Biobank genotyped about 500k participants using Applied Biosystems Axiom microarrays. Participants were subsequently sequenced by the UK Biobank Exome Sequencing Consortium. Axiom genotyping was highly accurate in comparison to sequencing results, for almost 100,000 variants both directly genotyped on the UK Biobank Axiom array and via whole exome sequencing. However, in a study using the exome sequencing results of the first 50k individuals as reference (truth), it was observed that the positive predictive value (PPV) decreased along with the number of heterozygous array calls per variant. We developed a novel addition to the genotyping algorithm, Rare Heterozygous Adjusted (RHA), to significantly improve PPV in variants with minor allele frequency below 0.01%. The improvement in PPV was roughly equal when comparing to the exome sequencing of 50k individuals, or to the more recent ~200k individuals. Sensitivity was higher in the 200k data. The improved calling algorithm, along with enhanced quality control of array probesets, significantly improved the positive predictive value and the sensitivity of array data, making it suitable for the detection of ultra-rare variants.
Collection of economic data using UB-04s: Is it worth the effort? Evidence from two clinical trials
Authors: Higuera Lucas , Ismyrloglou Eleni , Lu Xiaoxiao , Hinnenthal Jennifer , Holbrook Reece
Published: November 2022

Cost collection using UB-04 forms for economic evaluation is challenging, as UB-04 collection is time and effort intensive and compliance is imperfect. Alternative data sources could overcome those challenges. The objective of this study is to determine the usefulness of UB-04 data in estimating hospital costs compared to clinical case report form (CRF) data. Health care utilization costs were compared from financial information in UB-04s and from an assignment process using CRF data, from the WRAP-IT (23 infections) and the Micra IDE trials (61 adverse events and 108 implants). Charge-based costs were calculated by multiplying charges in UB-04s and hospital-specific Cost-to-Charge ratios from the Centers for Medicare and Medicaid Services cost reports. The cost assignment process used clinical information to find comparable encounters in real world data and assigned an average cost. Paired difference tests evaluated whether both methods yield similar results. The mean difference in total infection related costs between methods in the WRAP-IT trial was $152 +/-$22,565. In the Micra IDE trial, the mean difference in total adverse event related costs between methods was -$355 +/-$8,298 while the mean difference in total implant related costs between methods was $-3,488 +/-$13,859. Wilcoxon tests and generalized linear models could not reject the difference in costs between methods in the first two cases. Cost assignment methods achieve results similar to costs obtained through UB-04s, without the additional investment in time and effort. The use of UB-04 information for services that are not mature in a health care system may present unexpected challenges, necessitating a tradeoff with other methods of cost assignment.
Psychological distress, employment, and family functioning during the COVID-19 outbreak among recent immigrant families in Israel: Moderating roles of COVID-19 prevalence
Authors: Lee Tae Kyoung , Benish-Weisman Maya , Vos Saskia R. , Garcia Maria Fernanda , Duque Marquez Maria C. , Calderón Ivonne A. , Konshina Tatiana , Elizarov Einat , Schwartz Seth J.
Published: November 2022

Grounded in an ecodevelopment perspective, in the current study we examined unique and moderating effects of daily COVID-19 prevalence (social contexts) on effects of COVID-19 related risk and protective factors such as emotional distress (individual contexts) and employment (working from home and unemployment status; family contexts) on family functioning among 160 recent immigrant families in Israel. In general, results indicate several unique effects of COVID-19 related factors (such as COVID-19 emotional distress, unemployment, and remote work arrangements) on both parents’ and adolescents’ reports of family functioning. However, results indicated that there were more significant associations between COVID-19 factors (e.g., emotional distress and COVID-19 prevalence) and family functioning indicators with adolescents, than with parents. The effects of COVID-19 factors (e.g., emotional distress and remote work arrangements) were moderated by daily COVID-19 prevalence (new cases and deaths). We discuss ways in which interventionists can contribute to pandemic-related research to promote optimal family functioning among immigrant families.
“It’s the poverty”—Stakeholder perspectives on barriers to secondary education in rural Burkina Faso
Authors: Jabbarian Jan , Werner Luisa Katharina , Kagoné Moubassira , Lemp Julia Margarete , McMahon Shannon , Horstick Olaf , Kazianga Harounan , Kobiané Jean-François , Fink Günther , De Neve Jan-Walter
Published: November 2022

Universal primary and secondary education is a key target of the Sustainable Development Goals. While substantial gains have been made at the primary school level, progress towards universal secondary education has slowed, particularly in sub-Saharan Africa. In this study, we aimed to determine perceived barriers of secondary schooling in rural Burkina Faso, where secondary school completion is among the lowest globally (<10%). We conducted a two-stage qualitative study using semi-structured interviews (N = 49). In the first stage, we sampled enrolled students (n = 10), out-of-school adolescents (n = 9), parents of enrolled students (n = 5), parents of out-of-school adolescents (n = 5) and teachers (n = 10) from a random sample of five secondary schools. In a second stage, we interviewed key informants knowledgeable of the school context using snowball sampling (n = 10). Systematic analysis of the pooled sample was based on a reading of interview transcripts and coding of the narratives in NVivo12 using the diathesis-stress model. Recurring themes were classified using a priori developed categories of hypothesized barriers to secondary schooling. Major reported barriers included school-related expenses and the lack of school infrastructure and resources. Insufficient and heterogeneous French language skills (the official language of instruction in Burkina Faso) were seen as a major barrier to secondary schooling. Forced marriages, adolescent pregnancies, and the low perceived economic benefits of investing in secondary schooling were reported as key barriers among young women. Our results guide future interventions and policy aimed at achieving universal secondary education and gender equity in the region.
Dissection of Besnoitia besnoiti intermediate host life cycle stages: From morphology to gene expression
Authors: Ramakrishnan Chandra , Krishnan Aarti , Francisco Samuel , Schmid Marc W. , Russo Giancarlo , Leitão Alexandre , Hemphill Andrew , Soldati-Favre Dominique , Hehl Adrian B.
Published: November 2022

Cyst-forming Apicomplexa (CFA) of the Sarcocystidae have a ubiquitous presence as pathogens of humans and farm animals transmitted through the food chain between hosts with few notable exceptions. The defining hallmark of this family of obligate intracellular protists consists of their ability to remain for very long periods as infectious tissue cysts in chronically infected intermediate hosts. Nevertheless, each closely related species has evolved unique strategies to maintain distinct reservoirs on global scales and ensuring efficient transmission to definitive hosts as well as between intermediate hosts. Here, we present an in-depth comparative mRNA expression analysis of the tachyzoite and bradyzoite stages of Besnoitia besnoiti strain Lisbon14 isolated from an infected farm animal based on its annotated genome sequence. The B. besnoiti genome is highly syntenic with that of other CFA and also retains the capacity to encode a large majority of known and inferred factors essential for completing a sexual cycle in a yet unknown definitive host. This work introduces Besnoitia besnoiti as a new model for comparative biology of coccidian tissue cysts which can be readily obtained in high purity. This model provides a framework for addressing fundamental questions about the evolution of tissue cysts and the biology of this pharmacologically intractable infectious parasite stage.
Ele é os trabalhadores de Mafra… figuração das personagens coletivas em Memorial do Convento
Authors: Levécot Agnès
Published: November 2022

A figuração das personagens coletivas em Memorial do Convento constrói-se a partir de dois eixos que se cruzam e se completam um ao outro instaurando uma dialética entre singular e plural, individual e coletivo, e que tem por finalidade revalorizar os verdadeiros heróis da História. Este artigo descreve e analisa vários processos, semânticos, sintáticos e retóricos, que sustêm esta dialética, dentre os quais se destaca a exploração das potencialidades narrativo-axiológicas da enumeração.
Relationship between Human Resource Management Practices and Employee Engagement
Authors: MB Kavyashree , Kulenur Sridevi , P Nagesh , TS Nanjundeshwaraswamy
Published: November 2022

Purpose: Employee Engagement is mainstream attention for organizations in the current business scenario. The purpose of the current research focused on analysing the relationship between HRM Practices and Employee Engagement considering employees working in various IT industries, especially considering employees working in HR Department.
Design/Methodology/Approach: The research was cross-sectional in nature and survey method was employed to collect the data. Exploratory Factor Analysis, Confirmatory Factor Analysis, Structural Equation Modelling were used to analyse the hypothesis. Data was collected among 345 employees employed in the HR department of various private sector organizations.
Results: The model fit indices were adequate and acceptable. The model fit indices obtained were: CMIN/DF = 2.909; Goodness of Fit index (GFI) = 0.945; adjusted goodness of fit index (AGFI) = 0.909; incremental fit index (IFI) = 0.976; Tucker-Lewis index (TLI) = 0.981; comparative fit index (CFI) = 0.966; root mean square error of approximation (RMSEA) = 0.06.
Findings: The results of the study disclose that HRM practices and Employee Engagement were related to each other. HRM practices in organizations empowered employees and made them more engaged to perform better in their job roles. The study results imply that HRM practices need to be considered as priority in business organizations for the long term success.
Research Limitations: Non probabilistic sample method was adopted and it was possible to gather data only from 345 employees working in the HR Department of various private sector organizations.
Practical Implications: Business organizations are constantly working towards adopting new strategies and programs in the workplace to empower employees and keep them engaged in their work roles and responsibilities. Therefore, organizations to focus on human resource management practices and implement them effectively to make their employees committed and engaged towards their job. In this context, the present research attempts to analyse the association between human resource practices and employee engagement. The results provide insights for business managers on the importance of having effective Human Resource practices to enhance employees level of engagement towards their work roles.
Originality/ Value: Current research contributes to the existing literature on Human Resource Practices and Employee Engagement. While considering the current business scenario, it becomes very important to understand the role of human resource management practices on the engagement level of employees.
An empirical investigation of the impact of social media tool usage on employees work performance among Ghana Commercial Bank Workers
Authors: Mohammed Abubakari Sadiq , Ayambila Sylvester Nsobire , Lukman Sadia
Published: November 2022

Goal: The motivation of this paper is to forge and foster an insightful and comprehensive understanding of social media potential and its possible impact on Ghana Commercial Bank employees’ performance.
Design / Methodology / Approach: Five cities were strategically sampled using convenient sampling technique to represent the various diversifications in corporate compositions.  Data was collected from 249 workers of the Ghana Commercial Bank. The study utilized the structural equation modeling technique to construct and evaluate the proposed research model.
Results: Social media usage had a significant positive relationship with employee engagement and knowledge transfer. Knowledge transfer had no significant relationship with work performance and employee engagement had a significant positive relationship with work performance. Experience with social media had a significant moderating effect on relationship between knowledge transfer and work performance.
Research limitations/implications: The study covered employees from one bank and this has implications on generalization.  The study used cross sectional data and employed quantitative analysis. Mixed methods would have added some insights and longitudinal data could further unravel causal relationships among overtime.    
Practical implications: Social media platform managers and policy makers within the banking sector should proactively harness social media platform and utilize to benefit corporate bodies. Banking authorities and allied stakeholders should train workers to ensure positive inclination to social media usage.
Originality/Value: Contributes to theory by validating and establishing the theoretical model. The findings provide insights with respect to development and subsequent deployment of practical guidelines for successful integration of social media in enterprise activities.
Sex hormones and the risk of cardiovascular disease and mortality in male and female patients with chronic kidney disease: A systematic review and meta‐analysis
Authors: Oh Ester S. , Steele Cortney N. , You Zhiying , Nowak Kristen L. , Jovanovich Anna J.
Published: November 2022

Patients with chronic kidney disease (CKD) commonly experience sex hormone disturbances, which may be associated with the risk of cardiovascular disease (CVD) and mortality. This review aimed to systematically evaluate current findings on the association of sex hormone levels with the risk of CVD events and mortality (CVD and all‐cause) in the CKD population. Articles were systematically searched in CINAHL, Cochrane, and PubMed. A total of 1739 articles were independently screened by two reviewers and 17 prospective cohort studies were included. The clinical conditions of the patients were those with non‐dialysis CKD [mean/median estimated glomerular filtration rate (eGFR) between 15–51 ml/min/1.73 m2] and those on chronic dialysis (mean/median vintage between 6–125 months). The sample size ranged from 111 to 2419 and the mean/median age of subjects ranged from 52 to 72 years. The sex hormones studied were testosterone, estradiol, prolactin, dehydroepiandrosterone sulfate, and relaxin. A random‐effects model was used to generate a pooled hazard ratio (HR) to evaluate the association of total testosterone levels with the risk of CVD and all‐cause mortality. Most studies examined total testosterone levels (11 out of 17 studies) and studied only male patients (12 out of 17 studies). A lower total testosterone level was associated with a higher risk of CVD mortality [HR 4.37 (95% CI 1.40–13.65)] and all‐cause mortality [1.96 (1.35–2.83)] in males with CKD. To conclude, there is a strong need for additional studies examining the association of sex hormones with cardiovascular and mortality risk in female patients with CKD.
Ca2+‐activated Cl− channels (TMEM16A) underlie spontaneous electrical activity in isolated mouse corpus cavernosum smooth muscle cells
Authors: Lim Xin Rui , Drumm Bernard T. , Sergeant Gerard P. , Hollywood Mark A. , Thornbury Keith D.
Published: November 2022

Penile detumescence is maintained by tonic contraction of corpus cavernosum smooth muscle cells (CCSMC), but the underlying mechanisms have not been fully elucidated. The purpose of this study was to characterize the mechanisms underlying activation of TMEM16A Ca2+‐activated Cl− channels in freshly isolated murine CCSMC. Male C57BL/6 mice aged 10–18 weeks were euthanized via intraperitoneal injection of sodium pentobarbital (100 mg.kg−1). Whole‐cell patch clamp, pharmacological, and immunocytochemical experiments were performed on isolated CCSM. Tension measurements were performed in whole tissue. TMEM16A expression in murine corpus cavernosum was confirmed using immunocytochemistry. Isolated CCSMC developed spontaneous transient inward currents (STICs) under voltage clamp and spontaneous transient depolarizations (STDs) in current clamp mode of the whole cell, perforated patch clamp technique. STICs reversed close to the predicted Cl− equilibrium potential and both STICs and STDs were blocked by the TMEM16A channel blockers, Ani9 and CaCC(inh)‐A01. These events were also blocked by GSK7975A (ORAI inhibitor), cyclopiazonic acid (CPA, sarcoplasmic reticulum [SR] Ca2+‐ATPase blocker), tetracaine (RyR blocker), and 2APB (IP3R blocker), suggesting that they were dependent on Ca2+ release from intracellular Ca2+ stores. Nifedipine (L‐type Ca2+ channel blocker) did not affect STICs, but reduced the duration of STDs. Phenylephrine induced transient depolarizations and transient inward currents which were blocked by Ani9. Similarly, phenylephrine induced phasic contractions of intact corpus cavernosum muscle strips and these events were also inhibited by Ani9. This study suggests that contraction of CCSM is regulated by activation of TMEM16A channels and therefore inhibition of these channels could lead to penile erection.
Application of the patient-reported outcomes continual reassessment method to a phase I study of radiotherapy in endometrial cancer
Authors: Wages Nolan A. , Nelson Bailey , Kharofa Jordan , Meier Teresa
Published: November 2022

This article considers the concept of designing Phase I clinical trials using both clinician- and patient-reported outcomes to adaptively allocate study participants to tolerable doses and determine the maximum tolerated dose (MTD) at the study conclusion. We describe an application of a Bayesian form of the patient-reported outcomes continual reassessment method (PRO-CRMB) in an ongoing Phase I study of adjuvant hypofractionated whole pelvis radiation therapy (WPRT) in endometrial cancer (NCT04458402). The study’s primary objective is to determine the MTD per fraction of WPRT, defined by acceptable clinician- and patient-reported DLT rates. We conduct simulation studies of the operating characteristics of the design and compared them to a rule-based approach. We illustrate that the PRO-CRMB makes appropriate dose assignments during the study to give investigators and reviewers an idea of how the method behaves. In simulation studies, the PRO-CRMB demonstrates superior performance to a 5 + 2 stepwise design in terms of recommending target treatment courses and allocating patients to these courses. The design is accompanied by an easy-to-use R shiny web application to simulate operating characteristics at the design stage and sequentially update dose assignments throughout the trial’s conduct.
Consolidation of quality control material improves patient safety and supports sustainability
Authors: Menacho-Román Miriam , Ouriach Salma , Arribas Ignacio
Published: November 2022

Objectives

Quality control measurements are a keystone in daily routine laboratory workflows. This study evaluated the use of a consolidated quality control material for increasing efficiency while also reducing costs.

Methods

Quality control materials from two different manufacturers were chosen to evaluate efficiency in a test setting. A total of 23 clinical chemistry tests and 15 immunoassays were performed twice each day under routine conditions over a 10-day time period using an Abbott Alinity system.

Results

The data obtained showed a saving of between 40 and 100% depending on test criteria. The cost savings in waste reduction ranges between a factor of 5.4 for dead volume to 19.8 for consumables. No difference in quality performance were found.

Conclusions

Choosing a consolidated quality control material resulted in a higher efficiency, greater cost savings and higher sustainability while maintaining the same level of performance.
Pain in critically ill COVID-19 patients: An Italian retrospective study
Authors: Petrucci Emiliano , Cofini Vincenza , Pizzi Barbara , Cascella Marco , Marrocco Gioele , Ceccaroni Gianmaria , Necozione Stefano , Vittori Alessandro , Marinangeli Franco
Published: November 2022

We retrospectively analyzed the data from patients admitted to the intensive care unit (ICU) of the Hospital of L’Aquila during the first and second waves of pandemic to identify pain related to COVID-19. Pain was evaluated by using the Numerical Rating Scale, and the assessment for neuropathic disturbances of pain was performed with von Frey’s hair and Lindblom tests. Pain increased significantly during hospitalization (from 48% at hospital admission to 94.3% at ICU discharge). Female patients were affected by somatic pain in 32.8% of the cases and by somatic pain and pain with neuropathic features (NFs) in 23.5% of the cases, during the ICU stay. Somatic pain and pain with NFs affected more frequently patients with cardiological and respiratory comorbidities. Patients treated with continuous positive airway pressure via helmet had a higher frequency of somatic pain and pain with neuropathic disturbances (84 and 74%, respectively). The frequency of somatic pain and pain with neuropathic disturbances was lower in patients sedated with propofol combined with ketamine. Females have been associated with a higher risk of somatic pain and pain with NFs. Patients with cardiological and respiratory comorbidities undergoing noninvasive ventilation had higher levels of pain. As conclusion, ketamine may reduce the promotion or the worsening of pain in COVID-19 patients.
Fallen and Lost into the Abyss? A Mesolithic Human Skull from Sima Hedionda IV (Casares, Málaga, Iberian Peninsula)
Authors: Martinez-Sanchez Rafael M. , Bretones-García María Dolores , Valdiosera Cristina , Vera-Rodríguez Juan Carlos , López Flores Inmaculada , Simón-Vallejo María D. , Ruiz Borrega Pilar , Martínez Fernández María J. , Romo Villalba Jorge L. , Bermúdez Jiménez Francisco , Martín de los Santos Rafael , Pardo-Gordó Salvador , Cortés Sánchez Miguel
Published: November 2022

The presence of scattered prehistoric human bones in caves and sinkholes is common in many regions of Iberia. These are usually interpreted as erratic elements coming from burial contexts, usually collective associations. These burial contexts are very frequent in karst areas of the Iberian Peninsula since the Early Neolithic, mostly in the Late Neolithic, and Copper Age, while findings from earlier chronologies are much more unusual. In this work, we present partial remains of a human skull from the Mesolithic period, recovered from a cave in the Strait of Gibraltar area. Although there is no conclusive evidence pointing to a dismantled burial context, this constitutes an isolated find, where its final location appears to be consistent with gravitational fall followed by water transportation.
A Parade of Adornments (Isa 3:18–23): Daughters Zion in the Light of Gender and Material Culture Studies
Authors: Létourneau Anne , De Doncker Ellen , Roy-Turgeon Olivier
Published: November 2022

This article investigates the list of items of dress worn by the daughters Zion in Isa 3:18–23, as they are simultaneously stripped of them. It considers the poetic aspects of this list before turning to specific items, both jewelry and clothing, worn by the daughters in verses 18 and 22. These objects contribute to the complex characterization of the daughters Zion, as it poetically brings together a thick array of aesthetic, religious and traumatic meanings, and experiences.
Antitrinitarismo della prima età moderna e cultura italiana
Authors: Suitner Riccarda
Published: November 2022

This special issue is devoted to the influence of Italian culture on the Antitrinitarian movements that spread through Europe during the early modern period. One of the objectives is to go back to the period preceding the activities of Lelio and Fausto Sozzini, and to consider the influences of various trends in the Italian thought of the 15th and 16th centuries that made a crucial contribution to shaping Antitrinitarian ideas about Biblical exegesis, spirituality, baptism and the Trinity. Some papers also cover the phase following the international establishment of Socinianism. While for the first half of the sixteenth century there is a tendency to underestimate the Italian contribution to European Antitrinitarianism, the exact opposite is true for the period between the end of the sixteenth and the seventeenth centuries. The perception of Antitrinitarianism changes completely and, following the international affirmation of the Sozzini, is often mistakenly identified with Socinianism, taking the part for the whole (as is still often the case today on a historiographical level).
Italian Nicodemites amidst Radicals and Antitrinitarians
Authors: Overell M. Anne
Published: November 2022

Many Italians in exile ‚religionis causa‘ had learned to dissimulate well before they left their homeland: nicodemism was part of the necessary life preparation for becoming a radical or an antitrinitarian. Examining the careers of Italian refugees in the mid-sixteenth century, this essay shows that, by the time they crossed the Alps, they were already programmed to keep quiet, evade and deceive. Initially, exile felt like utopia: yet there was also a dawning realisation that restraint, evasion and silence would remain essential in relatively closed Swiss cities. When the exiles’ views turned to dangerous topics like the Trinity, baptism, the immortality of the soul or ‚il cielo aperto‘, they already knew the core nicodemite strategies: evasion, secrecy, ambiguity, pretence, being terse and hiding risky ideas within humanist dialogue form. Three examples are taken from those in and around Basel in the troubled 1550s: Bernardino Ochino, Celio Secondo Curione, and Lelio Sozzini. The burning of Miguel Servetus in nearby Geneva in 1553 appalled all three, crystallised their resistance to the dogma of reformers, and pointed to the dangers of not remaining a nicodemite. Concealment learned in Italy served to keep them alive in Swiss cities. Italian experience had also prepared them to write in forms whereby they might elude the attention of the authorities: spiritual letters (Curione), dialogues (Ochino) and ambiguous comments (Sozzini). All three spread their views by tactics known to nicodemites all over Europe but especially in Italy.
Camillo Renato tra stati italiani e Grigioni
Authors: Suitner Riccarda
Published: November 2022

The article draws a new profile of one of the main representatives of the first phase of the Italian Radical Reformation, Camillo Renato. It argues that humanist philological criticism, the ‚border‘ culture of the Valtellina, and even Venetian urban life contributed to the highly original character of his constantly evolving theology.
La nobiltà di Terraferma tra Venezia e le corti europee
Authors: Amighetti Paolo
Published: November 2022

In recent decades, research on the Venetian mainland state has underlined the tendency of subject elites to establish political relationships with foreign princes. This phenomenon was remarkably prominent in the cities of Brescia and Bergamo. The western periphery of the Venetian state was home to a wealthy and ambitious feudal nobility whose loyalty to the Most Serene Republic was very dubious. From the early decades of the 16th century, the Gambara family of Brescia maintained habitual contacts with the Imperial court and Spanish Lombardy to gain prestige and honour. In 1584 and 1596 two young brothers, Scipione and Lucrezio Gambara, were thus sent to the court of Emperor Rudolf II in Prague, where they served as pages. Although their brief experiences did not lead to noteworthy careers, their stay in Prague represented their family’s interest in preserving its long-standing Imperial allegiances. The rich family correspondence provides a detailed account of the two brothers’ life at the Imperial court, highlighting their family networks and relationship with courtiers and ambassadors. The Gambaras’ pro-Habsburg attitude ultimately had a negative impact on their relationship with Venice, since the Republic could not completely trust them as vassals. Nevertheless, the family’s allegiance to the House of Austria endured at least until the 1630s.
Una „razza mediterranea“?
Authors: Cerro Giovanni
Published: November 2022

This article reconstructs the anthropological debate on the Southern question, focusing on the decade between 1897 and 1907 and on three protagonists: the statistician and criminologist Alfredo Niceforo, the economist and politician Napoleone Colajanni and the anthropologist and psychologist Giuseppe Sergi. Sergi’s theories on the Mediterranean „race“, its African origin and role in the population and above all in the process of civilization of the European continent were used to support opposing positions: Niceforo referred to them to affirm the backwardness of the population of Southern Italy; Colajanni, by contrast, employed them to defend the dignity of the inhabitants of the South, against the advocates of the superiority and inferiority of different „races“. The analysis of these discussions shows how anthropologists and ethnologists, playing on the delicate balance between „race“ and „environment“, contributed – in often contradictory ways – to the socio-political project of defining Italian national identity in the early decades after Unification.
The dialogical semiosis of self-narrative in
Burning
Authors: Lee Yunhee
Published: November 2022

The first-person access to the self has been widely recognized by philosophers. But a competing idea arises, challenging the first-person givenness, from those who argue that self-interpretation and self-knowledge are acquired through the third-person perspective. I argue that these two dichotomous perspectives of the self can be mediated by the second-person perspective through dialogical semiosis of narrative. Peirce’s semiotic perspective on the self emphasizes the role of a semiotic subject that participates in sign processes as an interpreting agent. In this sense, the concept of self is acquired through semiosis of narrative and at the same time it is interpreted in narrative world, taking the role of character. It is character which makes a person identifiable as a person, since character is not substance but quality as a recognized pattern or type through time, which becomes a habit of act and thought, thus forming personal identity. Within this context, I argue that from the first-person perspective a deliberate subject of self as “subjective I” and from the third-person perspective a dynamic object of self as “objective I” are mediated by the relationship between self and other as an imaginary relation in narrative world, just like an imaginary line of identity, connecting word with thing. From the second-person perspective, oneself as another forms teridentity (co-identity) in textual world. I shall illustrate the interlock between the semiotic self and narrative identity through Peirce’s semiotic approach to the self and Ricoeur’s theory of narrative identity, analyzing the filmic narrative text of Burning (2018).
Nachhaltige Partnerschaft
Authors: Lange Bernd
Published: November 2022

The illusion that open and free trade, no matter with which partner, also creates fair and sustainable trade as well as eventually political change and a better, safer, world has long been put into question. Since the beginning of the Russian aggression against Ukraine, it has completely evaporated.

It would be wrong, however to completely abandon the concept of “change through trade” and to view trade policy solely as a protectionist element. Trade can indeed stimulate sustainable growth, bring about positive structural change and bind countries together more strongly – but only if the conditions are set correctly. And if both sides of the equation demonstrate the necessary will to do so. There has been a clear lack of this direction and will in trade policy and beyond in recent decades.

The challenges facing a modern and positive trade policy are many. Some of them are worth considering in detail before drawing conclusions for a reorientation of what remains the Union’s most effective geopolitical policy area.
МОДЕРНИЗАЦИЯЛАШ БОСҚИЧИДА СИЁCИЙ ПAPТИЯЛAP ФAOЛИЯТИНИ ҲУҚУҚИЙ ЖИҲАТДАН ТAPТИБГA СОЛИШНИНГ ЎЗИГА ҲОС ЖИҲАТЛАРИ
Authors: Юлдошбеков Авазбек Алишер
Published: November 2022

Ҳoзиpдa жaҳoн мaмлaкaтлapидa ўтгaн acpнинг cўнгги чopaгидa пapтиялapни ҳуқуқий тapтибгa coлиш пapтиялapгa дoиp қонунлapнинг фaқaт coн жиҳатидaн ўcиши билaн чeклaниб қoлмaди. Уни ўтгaн дaвpдaн ceзилapли тapздa фapқлoвчи янги тeндeнциялap пaйдo  бўлмоқда. Улapдaн биpи шyки, кoнcтитyциялap вa миллий қoнyнчилик cиёcий пapтиялapни инкop этa oлaдигaн вa тapтибгa coлиш oбъeктлapи фақат дaвлaт инcтитyтлapи бўлгaн вaқтлap ўтиб кeтди. Ҳoзиpдa cиёcий пapтиялap ҳaм кoнcтитyциявий, ҳaм мaxcyc ҳуқуқий тapтибгa coлишнинг мyҳим oбъeктигa aйлaнди.

Ушбу мақолада демократик партиялар фаолиятини такомиллаштириш ва ҳуқуқий тартибга солиш юзасидан олимларнинг баҳс ва мунозаралари ўрин эгаллаган.
ИГРЫ НА УРОКАХ МАТЕМАТИКИ
Authors: Хаитова Дилафруз Бекпулатовна
Published: November 2022

В статье анализируются различные подходы к содержанию и методам проведения дидактических игр на уроках математики в начальных классах. Дидактические игры служат к целям обучения, поэтому нужно их провести в занимательной форме, понятным образе, чтобы учащиеся активно тренировались в упражнениях, а также сформировались у них привычки обязательно выполнить каждое задание. Дидактические игры помогают лучше понять цель каждого урока, цели и задачи каждого упражнения. Эти игры также способствует повышению наглядности урока, включают в себя развитие речи и действий учащихся, вследствие которого у учащихся развиваются волевые качества (зрения, созерцания).
HOW BANKING MARKET COMPETITION AND BANK RELATIONSHIPS AFFECT SMALL FIRM LIQUIDITY
Authors: Odilov Boburjon Furkatovich , Shayakubov Davron Ravshanovich
Published: November 2022

This article aims to investigate the effects of relationship banking and banking market rivalry on small firm liquidity. Our major objective is to determine how bank market concentration and relationship banking affect the three crucial acts of small business liquidity (cash funds, line-ups of credit, and employment credit), both separately and collectively. Due to their significance for small firm ’s profitability, value, and sustainability, we concentrate on cash assets (Harford et al., 2008; Mach and Wolken, 2011). Despite this, there have been just two prior studies of small firm cash holdings that we are aware of (Garca-Teruel and Martnez-Solano, 2008; Faulkender, 2002). Likewise, even though credit lines remain also a shared source of small firm liquidness (Sufi, 2009), previous findings have normally aimed on credit line practice by large businesses (Acharya et al., 2013).
ЧУВСТВО ПАТРИОТИЗМА В КРЫЛАТЫХ СЛОВАХ
Authors: Исакова Гузалхон Неъматовна
Published: November 2022

Немаловажное значение придается воспитанию патриотизма молодого поколения. Прежде всего, актуален вопрос осознания этого чувства в буквальном смысле, сознательное усвоения его в деле воспитания подрастающего поколения. В статье речь идет о крылатых словах, отражающих чувство патриотизма. Они являются образными, лаконичными, краткими, смысловыми и поэтому легко усваиваются в нашем сознании благодаря тому, что связаны с каким-то событием или явлением, долго сохраняются в памяти и помогают глубоко впитать идею крылатых слов.
NEET САНАТЫНДАҒЫ ЖАСТАРДЫ ЖҰМЫСПЕН ҚАМТУДЫҢ БЕЛСЕНДІ ШАРАЛАРЫНА ТАРТУ МЕХАНИЗМІ ЖӘНЕ БАСҚАРУ ҚҰРАЛДАРЫ
Authors: Менлибаев Еркебулан Кайырбекович
Published: November 2022

Мақалада еліміздегі үлкен әлеуметтік топқа жататын жастардың өзекті мәселесі туралы жазылған. Ол не жұмыс істемейтін, не оқымайтын NEET санатындағы жастарды белсенді экономикалық нарыққа енгізу тетіктері зерттелді. Сонымен қатар, қазіргі таңда мемлекет тарапынан қабылданып жатқан шараларға (заңдар мен мемлекеттік бағдарламаларға) мониторинг жүргізілді. Қорытындысымен NEET санатындағы жастармен жұмыс жасауды жетілдіру бойынша тиісті ұсыныстар енгізілді.
ТРАНСФОРМАЦИЯ СЕМЕЙНЫХ ВЗАИМООТНОШЕНИЙ НА ОСНОВЕ КОНЦЕПТОВ ТРАДИЦИЙ И ОБЫЧАЕВ В РЕСПУБЛИКЕ УЗБЕКИСТАН
Authors: Акрамова Эльмира Иркиновна
Published: November 2022

В данной статье рассматриваются изменения семейных взаимоотношений и трансформация традиций и обычаев межпоколенных взаимоотношений особая роль в сохранении традиций и обычаев в узбекских семьях.
Traumatic abruption secondary to physical violence in the setting of low fibrinogen; brief report and review of literature
Authors: Patel Neil , Dikmen Sibel , Moretti Michael
Published: November 2022

Trauma is not uncommon in pregnancy. Trauma and its complications in pregnancy include premature rupture of membranes, pelvic fractures, uterine rupture, placental abruption, direct fetal injury, fetal death, or maternal death. We present a case of placental tear and bleed secondary to physical trauma and domestic abuse with counter-coup injury. This case report highlights a unique case in which the patient endured physical abdominal trauma at 32 weeks, who presented for decreased fetal movement and pelvic pressure, but denied vaginal bleeding or decreased fetal movement. Findings were significant for hypofibrinogenemia and change in ultrasound placental findings in the setting of reassuring fetal monitoring consistent with concealed traumatic abruption. This unique presentation adds to the literature because it will increase provider awareness of the subtle signs of intra-placental abruption.
Stajano, Fitz-Hugh, Curtis Syndrome. A review and case presentation
Authors: Escudero Fabián Rodríguez
Published: November 2022

Stajano, Fitz-Hugh, Curtis Syndrome is a rare clinical presentation of upper genital infections, characterized by few pelvic symptoms and perihepatitis attributed to direct bacterial infection. The perihepatic component usually presents as right hypochondrium pain, tenderness, and "violin strings" hepatophrenic adhesions. This atypical clinical presentation leads to frequent late or misdiagnoses, such as cholecystitis, appendicitis, pancreatitis, pyelonephritis, urolithiasis, or hepatophrenic abscesses. In this paper we carried out a historical review of the knowledge that have occurred over time, of this particular clinical presentation.
Explanatory basis of a national economy development
Authors:   Accounting chamber Ukraine, Didyk Andriy , Pogorelov Yuriy ,   Accounting chamber Ukraine
Published: November 2022

The article contains concepts of development for Ukrainian economy in the form of development explanatory basis. Such basis is important for defining development character, formalizing aims and principles of development, choosing its vectors and methods that implement such vectors into reality, building institutional support of development and effective employment of necessary resources. Using the general concepts of development studies, the content of notion “economic development” is specified. Difference between notions “economic development” and “economic growth” is considered. Via the qualitative features of general types of development, the character of development for Ukraine is suggested taking into account existing conditions and expected changes in Ukraine and abroad. It is shown that by the dynamics of changes development of the Ukrainian economy has to be revolutionary, by the vector – intensive one (aimed to the emergence of qualitative changes with a stable character due to implementing new technologies and renewing the production assortment of national producers), by the source (or the primary reason) – both exogenous and endogenous, by the view of development subject about changes over time – projective one, by the element of economic system that is mostly changed – structural (because the modern structure of Ukrainian economy causes some negative processes in it), by the development mechanism — bifurcational, by the measure of controllability – weakly managed, by the relationship between subject and object – both subject-object (subject of development is simultaneously an object of development), multi-vector and holistic. There are defined conditions of Ukrainian economy development regardless of its character (defined or any other): decrease of the administrative pressure under entrepreneurship (deregulation of the economy), increasing of an entrepreneur’s social role and his/hers comprehensive support. Defined character of the national economy development and conditions under which such development will exist should be taken into account in the development model. This will provide model adequacy to the modern conditions in Ukraine, model validity and its practical usability, ability to formulate particularly development tasks for every of its subjects.
Conceptual framework of analyzing development of threats to a social-economic system “city"
Authors:   National academy of internal affairs, Ukraine, Kozachenko Ganna , Romanovska Yuliya ,   Vinnitsa trade-economic institute of the State trade-economic university, Ukraine
Published: November 2022

There is expediency of building a conceptual framework of analyzing development of threats to a social-economic system “City" justified in the article. Such conceptual framework is considered a system of axioms, principles and concepts that are used to analyze the development of threats. The mentioned system covers cognitive, hermeneutical and methodological functions of mesolevel economical security studies. Constructs of the conceptual framework of analyzing development of threats to the social-economic system “City" are the system of logical statements. Operationalization of such statements allows to define threats to the social-economical system “City”, evaluate their character, scope and sources, analyze development of threats and forecast consequences of their implementation. Constructs of the conceptual framework are built by implementation of imperatives of protective and harmonization approaches and post neoclassic ontological principles, the main of which is methodological pluralism. The content and specific features of the considered constructs as a part of the conceptual framework of analyzing development of threats to a social-economic system “City" are considered in the article. Research thesaurus is improved by specifying content of notions “threat to the social-economic system “City”, “danger”, “risk”, “economic interest”. Characteristics of considered constructs and boundaries of their employment are defined. Connection measure for the considered constructs by the possibility of negative changes in the social-economic system “City” is shown. Operationalization of considered constructs as a part of the conceptual framework of analyzing development of threats to the social-economic system “City" will allow making the necessary tools to identify processes and phenomena in the external and internal environment of the social-economic system “City” as threats to such system and to analyze any particular threat and/or sets of such a threats.