bluuebunny/crossref_metadata_2025 huggingface dataset:
Radiological Modalities and Diabetes: A Review
Authors:   Healthcare Transformation, Riyadh Health Third Cluster, Ministry of Health, Riyadh 13717, Saudi Arabia, Kelis Khalid Mohammed , Almutairi Abdullah Dhaifallah ,   Healthcare Transformation, Riyadh Health Third Cluster, Ministry of Health, Riyadh 13717, Saudi Arabia, Aldrewesh Taghreed Abdullah ,   Healthcare Transformation, Riyadh Health Third Cluster, Ministry of Health, Riyadh 13717, Saudi Arabia
Published: February 2024

Diabetes has become a health care problem of increasing concern in the world as number of individuals with disease are on the rise over the past 2 decades. Imaging technologies are noninvasive tools which are currently receiving an increase significance to guiding physician in finding and therapeutic treatment of patients. Advanced imaging has upgraded our ability to assess the prospect of diabetics in patients. However, the capacity of imaging to detect the existence of osteomyelitis and myotitis does not automatically mean that it should be employ on a regular basis for tentative diagnosis of the diabetics. Diabetes is a multisystemic disease that exerts its effects through decrease insulin sensitivity causing various stages of metablilic conditions. The Pathogenesis of the complication related to diabetes is solely depended to duration of the disease with other health challenges which are refer to co-existing factors. The effects of long-standing effect of diabetes are usually associated with microvascular disease resulting to diabetic retinopathy nephropathy and cardiomyopathy. However, imaging performs an important part in diagnosis and follow-up of associated complications. This paper reviews the pathophysiology of diabetics, discuss the imaging appearance and provide detail review of the diagnostic image profile of patient with diabetics.
The Eyes have it: A Case of Ptosis and an Overview
Authors:   Clinical Professor and Attending Neurologist, University of Maryland Capital Region Health, Largo, Maryland, USA, A Zumo Lawrence , FAAN FAAN ,   Center for Epilepsy & Neurologic Diseases, Monrovia, Liberia, West Africa, J Zumo Malaika ,   Department of Biochemistry, College of Computer, Mathematical and Natural Sciences, University of Maryland, College Park, Maryland, USA
Published: February 2024

Ptosis, formerly blepharoptosis, has a very broad differential which can make correct and timely diagnosis difficult. This is a fairly common presenting conundrum in a busy clinical practice. A case of ptosis and fatigablity in a young female which evaded diagnosis for nearly two years is presented highlighting some of the diagnostic challenges as well as literature overview and current treatment strategies.
Health Seeking Behaviour among the Internally Displaced Persons in the North East Nigeria: Case Study of Tuberculosis Patients
Authors:   Sufabel Community Development Initiative, Gombe State, Nigeria, Abdulkarim Suraj , Stephen John ,   Janna Health Foundation, Adamawa State, Nigeria, Rahman Toufiq ,   Innovations & Grants Team, Stop TB Partnership, Geneva, Switzerland, Stevens Robert ,   Independent Consultant, Manchester, United Kingdom, Kuye Joseph ,   John Snow Inc. ( JSI), TB DIAH Project, Abuja, FCT, Nigeria
Published: February 2024

Over two million people are internally displaced in north-eastern Nigeria due to the complex humanitarian catastrophe. Overcrowded and unclean living conditions increase the risk of tuberculosis (TB) transmission, sickness, and death. The seeking behaviour of internally displaced persons (IDPs) in northeastern Nigeria was explored to improve disease surveillance and response in IDP camps and host communities.
Makna Denotasi, Konotasi, dan Mitos dalam Kidung Pepeling Karya Ki Anom Suroto Sebagai Media Pengingat Sholat dalam Pujian Pasca Adzan
Authors: Qurrota A’yuna Khaeroni  , Yuli Kurniati Werdiningsih  , Alfiah
Published: February 2024

Da'wah is an activity of voicing, calling, inviting or appealing to someone. In the Islamic religion, da'wah is an activity carried out to invite or distribute information related to the teachings of the Islamic religion. One example of da'wah is by providing information in the form of reminders to pray. Kidung Pepeling is a song initiated by Ki Anom Suroto which contains a warning message for carrying out prayers. This research regarding Kidung Pepeling by Ki Anom Suroto is intended to find out the meaning of connotation, denotation and myth contained in the lyrics. The scalpel used in this research is to use a literary critical approach, namely Roland Barthes' semiotic approach. This research was conducted using a qualitative descriptive method. The data collection process carried out was by collecting the lyric text of the Pepeling song as an initial stage. Then, the text that has been collected is first translated into Indonesian to simplify the research process. After that, the data analysis process in the form of the lyric text of the ballad is carried out based on the meaning, denotative, connotative and mythical meaning contained in the lyrics. The results obtained from this research were the discovery of semiotic signs in the form of deontation meaning, connotation meaning and mythical meaning in the Pepeling song.
Pengaruh Aplikasi Quizizz Sebagai Media Pembelajaran terhadap Keaktifan dan Prestasi belajar Siswa pada Pelajaran Kewirausahaan Kelas XII SMK N 8 Surakarta
Authors: Wahyudi Taufan Santoso  , Rita Dwi Nawanti  , Shodiq Purnomo  , Masduki
Published: February 2024

This research is an experimental research motivated by the low learning achievement of students in entrepreneurship subjects in class XII SMK N 8 Surakarta. This study aims to determine whether or not there is an influence of the use of quizizz learning media on the learning achievement of grade XII students in entrepreneurship subjects of SMK N 8 Surakarta. The variables of this study consist of two, namely independent variables include quizizz learning media and dependent variables include student learning achievement. The research method used in this study is quantitative research with the type of experimental research using the Pretest-Posttest Control Group Design research design, with pre-test, treatment, and post test stages. The population in this study was all 34 students of grade XII SK 3 SMK N 8 Surakarta. The sample of this study was class XII SK 3 SMK N 8 Surakarta as an experimental group with a total of 34 students. The data collection techniques used are questionnaires, observation sheets, and documentation. Data analysis techniques used by testing hypotheses using t-tests with independent sample t-test types. The results of this study show that learning achievement after the use of quizizz learning media can be categorized as high. The conclusion of this study is that quizizz learning media has an influence on the learning achievement of students in class XII entrepreneurship subjects of SMK N 8 Surakarta.
Strategi Distribusi Pemasaran Guna Meningkatkan Produk Perusahaan: Studi Kasus pada PT. Bintang Sidoraya
Authors: Faiz Hanan Fahreza  , Ratna Rostika
Published: February 2024

This internship report contains matters relating to marketing distribution strategies to improve products at PT. Bintang Sidoraya. This research uses marketing management theory and marketing mix strategies, namely segmenting, targeting and positioning strategies with a 4P marketing mix approach (Place, product, price and promotion). PT. Bintang Sidoraya is a company that operates as a beverage distributor company. Business activities at PT Bintang Sidoraya include purchasing, stock inventory and sales transactions. This research uses a qualitative approach with descriptive methods through interviews and direct observation. The conclusion of this research is that PT Bintang Sidoraya offers their products to a wide market segment and reaches all consumer classes. Market segmentation carried out by PT. Bintang Sidoraya is an offer at a more affordable price and is proven by PT. Bintang Sidoraya succeeded in identifying that they are a company that sells beverage products at affordable prices. This is one of the competitive advantages that can maintain the company's existence in a sustainable manner.
Nursing Services in Handling Tuberculosis Patients
Authors: Nurliana  , Sholahuddin Agus , Hariyanto Tommy
Published: February 2024

Nursing Staff Services in Handling Tuberculosis Patients at the Darul Imarah Health Center, Aceh Besar District, due to the limited ability of human resources to carry out data collection actions so that it is not yet known in real terms about the examination and treatment that will be carried out. As for the formulation of the problem 1) How is the Service of Nursing Staff in Handling Tuberculosis (TB) Patients at the Darul Imarah Health Center, Aceh Besar District; 2) What are the Supporting and Inhibiting Factors for Nursing Services in Handling Tuberculosis (TB) Patients at the Darul Imarah Health Center in Aceh Besar District. While the objectives of the problem 1) To describe and analyze the Services of Nursing Staff in Handling Tuberculosis (TB) Patients at the Darul Imarah Health Center, Aceh Besar District; 2) To describe and analyze what are the Supporting and Inhibiting Factors for Nursing Services in Handling Tuberculosis (TB) Patients at the Darul Imarah Health Center, Aceh Besar District. Theoretical benefit, as an effort of researchers in transforming this research so that it becomes a contribution of thought to the development of studies to realize the systematic implementation of public policies with regard to a concept and/or theory that is developed through understanding, understanding in Nursing Services for Tuberculosis Patients at the Darul Imarah Health Center, Aceh Besar District. Practical Use. It is hoped that this research can serve as input as a basis for consideration in efforts to combat tuberculosis and resources for tuberculosis control at the Darul Imarah Health Center in Aceh Besar District. The research approach was carried out using a descriptive qualitative research approach, through research with benefits information using interview techniques, documentation, observations and conclusions were carried out to obtain Nursing Services for Tuberculosis Patients at the Darul Imarah Health Center, Aceh Besar District. This includes increasing the number of adequate nursing staff, increasing accessibility to training and education related to prevention, as well as increasing supervision and supervision of nursing staff for Tuberculosis Patients
Management of the Jaranan Market Cultural Village
Authors: Kanata Happy Evryda , Sukowati Praptining , Widjajani Roos
Published: February 2024

The importance of community participation in the development process means that community participation needs to be developed and improved in quality. To improve the quality of community participation, the role of sub-district level government as the lowest level government organization is needed. It is hoped that this will have implications for increasing community welfare starting from the bottom so that each region's various local potentials can be better absorbed. Through Blitar Mayor Regulation Number 6 of 2022 concerning the Cool Neighborhood Program, the Blitar City Government is trying to increase the participation of the Blitar City community starting from the neighborhood association (RT)level to be directly involved in the development process in their respective RT areas, coordinated by the respective Subdistrict Governments.This research aims to describe and analyze the implementation of management policies for the Pasar Jaranan Cultural Village in Blitar Village, along with supporting and inhibiting factors. This research uses a qualitative approach with research procedures that produce descriptive data. The research location is in Blitar Village, Sukorejo District, Blitar City. Data sources include primary and secondary data. The data collection techniques used were observation, interviews and documentation. The interactive data analysis technique model from Miles, Huberman, and Saldana (2014) is used for data analysis techniques in this research. The research results show that implementing the Cool Neighbors Association Program in the Blitar Subdistrict to manage the Pasar Jaranan Cultural Village has gone quite well. The Blitar Subdistrict Government has worked according to its commitment, supported by active community participation. However, activity output is still found to be unsustainable. Apart from that, it is also known that there are factors that support the implementation of this program, namely high enthusiasm, initiative and community self-help, and the inhibiting factor is the lack of insight and understanding of the community regarding the concept and management of a cultural village.
Impact of Blockchain Technology on Supply Chain Management Efficiency and Transparency in Pakistan
Authors: Huzaifa Imran
Published: February 2024

Abstract

Purpose: The aim of the study was to influence the impact of blockchain technology on supply chain management efficiency and transparency

Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.

Findings: A study on the impact of blockchain technology on supply chain management in Pakistan revealed significant improvements in efficiency and transparency. Through blockchain integration, supply chain processes experienced reduced delays and increased automation, leading to streamlined operations. Transparency was notably enhanced, with real-time tracking of goods and secure data sharing among stakeholders, mitigating risks of fraud and error. These findings suggest that adopting blockchain technology holds promise for enhancing supply chain management in Pakistan by fostering greater efficiency and transparency.

Unique Contribution to Theory, Practice and Policy: Diffusion of innovations theory, information processing theory & resource dependency theory may be used to anchor future studies on the impact of block chain technology on supply chain management efficiency and transparency. Encourage supply chain stakeholders to adopt blockchain solutions for enhanced transparency, traceability, and efficiency. Advocate for regulatory frameworks that promote the adoption of blockchain technology in supply chains while addressing concerns related to data privacy, interoperability, and standardization.
Investigating the Effects of Sustainability Initiatives on Supply Chain Resilience and Performance in Indonesia
Authors: Basuki Ahmad
Published: February 2024

Abstract

Purpose: The aim of the study was to investigating the effects of sustainability initiatives on supply chain resilience and performance

Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.

Findings: The investigation into sustainability initiatives' effects on supply chain resilience and performance revealed significant benefits. Companies that integrated sustainable practices into their supply chain operations experienced improved resilience against disruptions, such as natural disasters or supply chain disruptions. Additionally, these initiatives often led to enhanced operational performance, including cost savings, efficiency improvements, and better relationships with stakeholders. Overall, the findings suggest that integrating sustainability into supply chain management can contribute positively to both resilience and performance outcomes.

Unique Contribution to Theory, Practice and Policy: Resource-based view (RBV) theory, institutional theory & contingency theory may be used to anchor future studies on investigating the effects of sustainability initiatives on supply chain resilience and performance. Practitioners should prioritize the implementation of integrated sustainability strategies that align with organizational goals and supply chain objectives. Policymakers play a critical role in creating an enabling environment for sustainable supply chain management practices.
Exploring the Potential of Gold Nanoparticle Technology and the Pan-Coronavirus Vaccine
Authors: Lee Chanung
Published: February 2024

When facing the threat of viral COVID-19 mutations, current objectives remain rooted in creating a universal vaccine, or a pan-coronavirus vaccine, that is effective against all COVID-19 variants. While most current COVID-19 vaccines use mRNA, nonreplicating viral vectors, inactivated vaccines, and protein subunits, nanotechnology is emerging as a viable resource for developing protective immunity against COVID-19. With the possibility of new COVID-19 variants emerging, increasing funds to further gold nanoparticle research is as crucial as technological innovation. This study hypothesizes that using a combination of “push” and “pull” methods to increase R&D incentives in gold nanoparticle research can take pan-coronavirus vaccine developments one step closer to boosting long-term immunization and universal applicability. This study's limitations include the immediacy of the COVID-19 pandemic and an inability to evaluate nanotechnology vaccinations after they have been put on the market. With its emphasis on funding gold nanotechnology research via “push” and “pull” incentives, this study’s implications include furthering global partnerships and contributing to the pan-coronavirus vaccine development with sensitivity to the rising risk of mutations and immunocompromised individuals.
Applications of Probability in Real World Examples
Authors: Gandhi Jayan , Sedrakyan Hayk
Published: February 2024

Probability is one of the most important subjects studied in mathematics because of how useful it is in the modern world. On a daily basis, most people have to deal with something that involves probability. For example, some of the simplest things such as flipping a coin has to deal with probability. In this research paper, we will look at some examples of probability with applications to the real world.
Machine Learning in Depression Detection: Exploring the Possibilities
Authors: Kandula Anvitha
Published: February 2024

This paper aims to explore the future possibilities of using machine learning to aid in diagnosing and discovering underlying mental illnesses such as depression, anxiety, etc. This is done by testing the current limitations of machine learning when it comes to emotion detection and testing the effectiveness of machine learning in this area using a Python program.
A Quantitative Analysis of Gender Differences in the Improvement of High School Distance Runners
Authors: Whittle Alexandra
Published: February 2024

This paper presents a quantitative analysis of the gender differences in the improvement of high schooldistance runners to better understand the impact of gender on athletic performance. There is a lack of gender-specific studies regarding athletic performance in existing research, especially at the high school level. There is alsoa clear gap in available research comparing the improvement of males and females. To close this gap, this researchanalyzes 1600-meter race times of high school runners from MileSplit, a running time database. These times wereimported and analyzed by a Python code and Excel graphs. Results reveal that male runners experience greaterimprovement than females during high school and that elite runners improve at a faster rate than non-elite runners.These results can be connected back to the difference in growth patterns and hormonal processes of each gender.This research addresses gender-based performance differences among high school runners and serves as a basis forfuture investigations on athletic performance gaps between genders.
The Social Determinants of Health and Genocide: Towards a Public Health Integrated Framework of Genocide and Mass Violence
Authors: Persad Sian , Xu Cheng
Published: February 2024

This paper makes a normative argument about transformations of public health as a necessary condition required in any transitional justice process. We seek to bridge the gap between the fields of genocide and public health to understand the recursive relationship between genocide and the social determinants of health. We show that structures and institutions established during genocide create enduring impacts on the public health outcomes of victim and survivor groups even after the ousting of the original perpetrators. Our comparative analysis of the Rwandan Genocide and the colonial genocide of Indigenous communities in Canada surveys the available public health literature and argues that perpetrators of genocide deliberately design public health systems for the explicit purposes of destroying target communities over the longue durée. When these systems are insufficiently transformed, post-genocide societies face significant barriers to transitional justice and reconciliation as a direct result of their impacts on survivor communities. In Rwanda, delayed addressal of the HIV/AIDS epidemic engineered by the Hutu Power regime continued to victimize Tutsi women decades after the mass killings have ended; in Canada, legacies of family separation and the Indian Residential School system have straddled Indigenous communities with high rates of comorbidities and early death consistent with colonial genocide policies.
“Genocide of the Soviet People”: Putin’s Russia Waging Lawfare by Means of History, 2018–2023
Authors: Weiss-Wendt Anton
Published: February 2024

This article exposes the political underpinnings of the term “genocide of the Soviet people,” introduced and actively promoted in Russia since 2019. By reclassifying mass crimes committed by the Nazis and their accomplices against the civilian population—specifically Slavic—as genocide, Russian courts effectively engage in adjudication of the history of the Second World War. In the process, genocide trials, ongoing in twenty-five Russian provinces and five occupied Ukrainian territories, present no new evidence or issue new indictments, thus fulfilling none of the objectives of a standard criminal investigation. The wording of the verdicts, and a comprehensive political project put in place to promote it, suggests three main objectives behind the novel genocide of the Soviet people trope, absolving the Soviet Union of responsibility for the outbreak of the Second World War, counterbalancing the efforts of the Ukrainian government to seek international recognition of Holodomor as an act of genocide, and drawing a parallel between Nazi crimes and those ascribed to “Ukrainian neo-Nazis.” Russian genocide trials are a crass example of sham justice and a manifestation of lawfare.
A Comissão de Constituição, Justiça e Cidadania da Câmara dos Deputados e as chamadas ilusões constitucionais
Authors: Valença Daniel Araújo , Diniz Diana Melissa Ferreira Alves
Published: February 2024

O objetivo do presente trabalho é realizar uma compreensão da natureza da Comissão de Constituição, Justiça e Cidadania da Câmara dos Deputados (CCJC) por meio do conceito de “ilusões constitucionais”, conforme proposto por Lênin. Para concretizar a pesquisa, valeu-se da orientação teórico-metodológica do materialismo histórico-dialético, sendo a pesquisa teórica de abordagem qualitativa e os procedimentos técnicos bibliográficos e documentais. Partiu-se da hipótese de que a CCJC se apresenta como instituição de Estado inserida na totalidade social do modo de produção capitalista e, como tal, é permeada por contradições e interesses de classes em luta, não devendo ter seus pareceres idealizados e analisados fora da conjuntura em que foram estabelecidos. Nesse sentido, verificou-se que influências externas e a exiguidade do tempo para pareceres e debates marcam a atuação da referida comissão. Como síntese das conclusões, confirmou-se a hipótese no sentido que é necessário retirar as lentes ilusórias do jurídico para compreender a CCJC tal qual ela realmente é. A originalidade do artigo reside na abordagem materialista da Teoria Constitucional Aplicada.
Proteção interamericana aos direitos humanos da mulher: diretrizes para a implementação de leis e políticas públicas de gênero, com ênfase para o Brasil
Authors: Ribeiro Camila Carvalho , Moreira Thiago Oliveira
Published: February 2024

Enfocam-se, no presente estudo, as diretrizes do Sistema Interamericano de Direitos Humanos para a implementação de leis e políticas afirmativas de gênero, com ênfase para a atuação perante o Brasil. Além disso, analisa-se o resultado prático desses esforços no país, trazendo à baila uma série de políticas desenvolvidas diante do caso Maria da Penha Maia Fernandes. Para tanto, por meio de estudo doutrinário e de análise estatística, trabalhar-se-á, a priori, o conceito de equidade e direito às diferenças, que deflagram a importância de uma “discriminação positiva” para a concretização de políticas públicas mais justas e eficientes, que considerem as peculiaridades de cada indivíduo ou grupo social e suas vulnerabilidades. Superada essa análise conceitual, por meio de pesquisa teórica (bibliográfica e documental), votar-se-á para o Sistema Interamericano de proteção ao gênero feminino, a partir de dois postos-chaves: i) breve contextualização histórica, social e filosófica dos direitos humanos e dos direitos humanos da mulher e ii) recorte histórico-normativo. O propósito é explorar a razão relativa aos fenômenos envolvendo as leis e políticas de gênero implementadas. Ao final, por meio de investigação documental, serão abordadas as principais diretrizes propostas pela CIDH na temática, as quais resultaram na criação uma série de leis e políticas afirmativas no Brasil, observando-se a progressão da realidade brasileira ao longo do tempo, em matéria de políticas de gênero, concluindo-se que, embora as leis e políticas afirmativas sejam crescentes, a violência de gênero no Brasil, ainda, é preocupante.
Effects of fermented palm kernel cake in acidic and basic solutions on the performance of broiler chickens
Authors: SEVERIN Teufack , BERTINE Noumbissi Marie Noël , RUBEN Ngouana Tadjon , GILCHRIST chouan Deffo , WILFRIED Edie Nounamo Langston , EVARISTE Taboumda , ROMARIO Tindo Tsamene , RAPHAËL Kana Jean
Published: February 2024

Palm kernel meal is a by-product used very sparingly in poultry feed, due to its low nutritional value and gravelly appearance which could be improved by physical or chemical treatments. The aim of this study was to assess the effect of palm-kernel meal fermentation period on its nutritional value and growth performances of broiler chickens. The treatment consisted of fermenting palm kernel meal in a solution of humic acid (HA) or limestone, for 0, 2, 4 and 6 days. A control ration without palm kernel meal (R0) was compared to rations containing 15% unfermented palm kernel cake (R0+) and 15% fermented palm kernel cake in humic acid and limestone solutions. Each experimental ration was randomly assigned to 8 chicks in 4 experimental units of 02 chicks each, repeated 4 times per a 2×3 factorial design (2 fermentation modes and 3 fermentation period). The main results showed that fat content (13.04%) and metabolizable energy (5314 Kcal/kg DM) of palm kernel meal were higher when fermented in humic acid for 6 days. Fermentation in the basic solution for the same period (6 days) increased protein (13.52%) and cellulose (24.21%) contents. Whatever the fermentation mode, the digestive utilization coefficient of dry matter, organic matter, crude protein and crude cellulose increased with the fermentation period. Fermentation mode and period had no significant effect on growth performance. However, growth characteristics tended to improve with fermentation period. In conclusion, fermentation of palm kernel in humic acid and limestone solutions improved significantly (P<0.05) the digestibility of all feed components, enabling chickens to take advantage of the nutrients for better growth performances.
Selected Elements of Governance Under Conditions of Conflicts and Crises, And Sustainable Development of Enterprises and Corporations
Authors: WACHOL Jerzy
Published: February 2024

The study presents selected elements of governance in the face of armed conflict, economic and social crises, taking into account sustainable development in the face of a changing environment and climate. Socio-economic data and trends of changes in the global economy were presented, where the 2020 crisis was followed by economic upturn in 2021 and 2022.
The Impact of Gender Quotas on The Management of Local Government Units
Authors: Roman Magdalena
Published: February 2024

Human capital plays a crucial role in the management of local government units. The article presents the impact of human capital management – gender quotas on the financing of local government units – municipal, county, provincial councils. The topic of gender quotas in local government is not often discussed. Financing local government units in a changing economic landscape becomes increasingly challenging. Decisions of local government officials heading local government units are influenced by many factors including gender structure and changing environment. The structure of councilors in all three local government units by male and female is presented. The structure of councilors in the above-mentioned units is presented on the basis of data from the year 2021.
Safety Promotion as a Key Element of the Workplace Accident Reduction Strategy in Polish Enterprise
Authors: MICHALIK Joanna , KRAKOWIAK Marlena , WOJTYTO Dorota , BERSKI Szymon
Published: February 2024

Safety promotion issues belongs to a group of important elements affecting the activities of every organization and are widely discussed among modern scientists and experts. Building a culture of occupational safety translates primarily into a decreasing number of accidents at work and raises the company’s reputation in the market and among the employees. Therefore, a preliminary analysis of the state of occupational health and safety in Poland was made based on statistical data on the number, severity, causes of accidents and occupational diseases – their structure and indicators. The methods of shaping the safety culture in the company, methods of promoting safety and their effectiveness were reviewed. The study was based on data from industry and the Central Statistical Office in Poland. The analysis of the company's health and safety promotion activities and their effects allows to conclude that these efforts bring the desired result. It can be achieved thanks to perseverance, continuous improvement, multi-level actions and the commitment of both the management and especially employees. The obtained results can be useful for employers and occupational safety and health services due to the importance of unconventional ideas and attitudes and cooperation of all stakeholders in field of work safety.
Analysis of Selected Hazards and Working Environment Factors: The Case of a Production Plant in Poland
Authors: WOJTYTO Dorota , MICHALIK Joanna , BERSKI Szymon
Published: February 2024

The analysis of the working environment factors is an extremely broad topic, especially as each enterprise is characterised by a different safety management system and the presence of various risks. Due to the specific nature and profile of manufacturing or service companies, as well as the different working processes, more attention is paid to physical, chemical or psychophysical risks. This paper presents the results of a study on the measurement and analysis of temperature and airflow at a selected workstation and an analysis of the risks involved. The dissertation is a continuation of the study on physical factors in the selected production plant. Previous studies have been carried out regarding the noise measurement. The motivation for the study was to analyse the correctness of the provision of adequate temperature and airflow in the workplace at the selected workstation and actions to improve the working conditions of the employee in this respect.
Niraparib and Abiraterone Acetate (Akeega)
Authors: CADTH
Published: February 2024

CADTH recommends that Akeega be reimbursed by public drug plans for the first-line treatment of metastatic castration-resistant prostate cancer (mCRPC) if certain conditions are met.

Akeega should only be covered to treat patients with mCRPC who have BRCA mutations, have not been treated with an androgen receptor pathway inhibitor (ARPi) for earlier stages of prostate cancer, and have not received treatments that affect the entire body for mCRPC (except for treatments of less than 4 months with abiraterone acetate and prednisone) or a poly-(ADP-ribose) polymerase inhibitor (PARPi) for mCRPC. Moreover, patients should be in relatively good health.

Akeega should only be reimbursed if it is prescribed by a clinician with expertise in treating prostate cancer with systemic anticancer therapy and if the cost of Akeega is reduced. Akeega should not be reimbursed when used in combination with other anticancer drugs.
Sacituzumab Govitecan (Trodelvy)
Authors: CADTH
Published: February 2024

CADTH recommends that Trodelvy should be reimbursed by public drug plans for the treatment of adult patients with unresectable locally advanced or metastatic hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative (IHC 0, IHC 1+, or IHC 2+/ISH–) breast cancer who have received endocrine-based therapy and at least 2 additional systemic therapies in the metastatic setting, if certain conditions are met.

Trodelvy should only be covered to treat adult patients with unresectable locally advanced or metastatic HR-positive, HER2-negative breast cancer who have been previously treated with at least 1 taxane, at least 1 prior anticancer hormonal treatment, and at least 1 cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor in any setting, have experienced treatment failure after 2 to 4 prior systemic chemotherapy regimens for metastatic disease, and have good performance status.

Trodelvy should only be reimbursed if it is prescribed by clinicians with expertise and experience in treating breast cancer in approved centres, and if the price of Trodelvy is reduced.
EXPLORANDO O POTENCIAL TRANSFORMADOR DA METABOLÔMICA PERSONALIZADA NA OSTEOGÊNESE IMPERFEITA
Authors: Carvalho Maria Eduarda Ferreira de , Binda Vitória Neves , Destefani Vinícius Côgo , Destefani Afrânio Côgo
Published: February 2024

O artigo científico aborda a importância da metabolômica como uma ferramenta essencial na pesquisa biomédica, destacando seu papel na ampliação do conhecimento molecular sobre doenças e no avanço da medicina personalizada. A metabolômica personalizada é reconhecida por seu potencial significativo em melhorar a assistência à saúde, identificando biomarcadores, alvos terapêuticos e compreendendo variações na resposta e metabolismo de medicamentos. O estudo ressalta a relevância da metabolômica na pesquisa biomédica, especialmente no contexto da Osteogênese Imperfeita (OI). Reconhecendo a capacidade da metabolômica personalizada de ampliar o conhecimento molecular sobre a OI, identificando metabólitos específicos, potenciais biomarcadores e alvos terapêuticos para essa condição genética rara, o estudo destaca, também, a necessidade de superar desafios, como a padronização de protocolos e a complexidade da análise de dados, enfatizando a importância da colaboração entre cientistas, profissionais médicos e pacientes para traduzir essas descobertas em práticas clínicas eficazes no manejo da OI.
The Long Game to mitigate earth system tipping points
Authors: Bhowmik Avit , McCaffrey Mark S. , Kunkel Oliver
Published: February 2024

Abstract. The devastating impacts of triggering earth system tipping points are unfolding, not only in physical and infrastructural losses and damages, but also in increasing eco-anxiety and trauma. Here we present and discuss “The Long Game”, i.e. a concept of gamifying education for triggering action at scale and self- efficacy as well as facilitating active engagements in real-world socio-ecological projects through collaborations with transformation actors. The Long Game can serve as a pedagogical entry point for hosting and fostering unlearning and double loop learning processes in the education system. This in turn can trigger self-reinforcing positive social tipping across wider socio-behavioral, economic, technological and political domains for rapid mitigation of earth system tipping points as well as for healing eco-anxiety and trauma.
Automated static magnetic cleanliness screening for the TRACERS small-satellite mission
Authors: Dorman Cole J. , Piker Chris , Miles David M.
Published: February 2024

Abstract. The Tandem Reconnection and Cusp Electrodynamics Reconnaissance Satellites (TRACERS) Small Explorers mission requires high-fidelity magnetic field measurements for its magnetic reconnection science objectives and for its technology demonstration payload Magnetometers for Innovation and Capability (MAGIC). TRACERS needs to minimize the local magnetic noise through a magnetic cleanliness program such that the stray fields from the spacecraft and its instruments do not distort the local geophysical magnetic field of interest. Here we present an automated magnetic screening apparatus and procedure to enable technicians to routinely and efficiently measure the magnetic dipole moments of potential flight parts to determine whether they are suitable for spaceflight. This procedure is simple, replicable, and accurate down to a dipole moment of 1.59 × 10−3 N m T−1. It will be used to screen parts for the MAGIC instrument and other subsystems of the TRACERS satellite mission to help ensure magnetically clean measurements on orbit.
How to mitigate flood events similar to the 1979 catastrophic floods in the lower Tagus
Authors: Fernández-Nóvoa Diego , Ramos Alexandre M. , González-Cao José , García-Feal Orlando , Catita Cristina , Gómez-Gesteira Moncho , Trigo Ricardo M.
Published: February 2024

Abstract. The floods that struck the lower Tagus valley in February 1979 correspond to the most intense floods in this river and affected the largest number of people in a river flow event in Portugal during the last 150 years. In fact, the vast area affected significantly impacted circa 10 000 people in the lower Tagus sector (and an additional 7000 in other regions of Portugal), including thousands of people evacuated or made homeless. In this context, the present study focuses on an in-depth analysis of this event from a hydrodynamic perspective by means of the Iber+ numerical model and on developing strategies to mitigate the flood episodes that occur in the lower section of the Tagus River using the exceptional floods of February 1979 as a benchmark. In this sense, dam operating strategies were developed and analyzed for the most important dam along the Tagus River basin in order to propose effective procedures to take advantage of these infrastructures to minimize the effect of floods. Overall, the numerical results indicate a good agreement with watermarks and some descriptions of the 1979 flood event, which demonstrates the model capability to evaluate floods in the area under study. Regarding flood mitigation, results obtained indicate that the frequency of floods can be reduced with the proposed strategies, which were focused on providing optimal dam operating rules to mitigate flooding in the lower Tagus valley. In addition, hydraulic simulations corroborated an important decrease in water depth and velocity for the most extreme flood events, and also a certain reduction in the flood extension was detected. This confirms the effectiveness of the proposed strategies to help in reducing the flood impact in the lower Tagus valley through the efficient functioning of dams.
Mengenal tokoh pahlawan Indonesia merupakan bagian dari pembelajaran sejarah dan pembentukan identitas nasional. Dengan mengenal, jiwa rela berkorban dan cinta Tanah Air dapat tertanam dalam setiap insan bangsa Indonesia, terutama generasi muda sebagai pe
Authors: Nugraha Rifky , Astuti Hesti , Istianah Raray
Published: February 2024

Mengenal tokoh pahlawan Indonesia merupakan bagian dari pembelajaran sejarah dan pembentukan identitas nasional. Dengan mengenal, jiwa rela berkorban dan cinta Tanah Air dapat tertanam dalam setiap insan bangsa Indonesia, terutama generasi muda sebagai penerus bangsa. Tingkat pengenalan generasi muda terhadap tokoh-tokoh pahlawan nasional masih rendah. Metode yang di gunakan dimulai dari jenis penelitian yang akan di gunakan, objek penelitian yang akan diteliti lebih dalam, subjek penelitian yang melibatkan beberapa pihak, lokasi penelitian, pengambilan sampel penelitian, Teknik pengumpulan data, Teknik analisis data, penarikan kesimpulan dan alur perancangan desain. Tujuan dari penelitian ini diharapkan dapat menggugah minat anak-anak Indonesia dan mempelajari kisah perjuangan dan kepribadian, serta nilai keteladanan pahlawan Indonesia salah satunya R.A Kartini melalui komik digital.

Kata Kunci: Pahlawan Nasional Indonesia, R.A Kartini, Komik Digital
ANALISIS IKLAN LAYANAN MASYARAKAT BERBASIS DIGITAL DALAM MEMBANGUN PEMAHAMAN MASYARAKAT TENTANG KEJAHATAN HOAKS
Authors: Yunita Gesnida
Published: February 2024

This study aims to analyze the effectiveness of digital-based public service advertisements in building public understanding of hoax crimes. Hoax crimes have become an increasingly worrying issue in today's digital era, where false information can quickly spread and affect people's perceptions and actions. Public service advertisements have the potential to become important tools in efforts to combat the spread of hoax crimes by providing accurate and educative information. This study uses a qualitative approach with content analysis methods to explore the meaning and messages contained in public service advertisements related to hoax crimes. Data is collected through searches of public service advertisements on digital platforms, such as social media, government websites and video sharing channels. The selected advertisements are then analyzed to identify communication strategies, core messages, and approaches used to build public understanding of hoax crimes. The results of the analysis show variations in the communication strategies used in public service advertisements. Some advertisements focus on providing factual information about hoax crimes and their negative impacts, while others place more emphasis on using emotional narratives to arouse feelings of concern and the need to be careful in sharing information. The core messages in advertisements tend to highlight the importance of verifying information before trusting and disseminating information, as well as inviting the public to actively participate in fighting hoax crimes. The conclusion of this study is that digital-based public service advertisements can be effective in building public understanding of hoax crimes by providing clear, accurate and relevant information.
THE MAIN PROBLEMS AND WAYS OF DEVELOPMENT OF THE EXCHANGE MARKET OF THE REPUBLIC OF KAZAKHSTAN
Authors:   Al-Farabi Kazakh National University, Almaty city, Kazakhstan, Kerimbek G. , Mahfudz A. ,   University of Darussalam Gontor, Demangan city, Indonesia, Yerkhanova B. ,   Al-Farabi Kazakh National University, Almaty city, Kazakhstan
Published: February 2024

Бұл мақалада Қазақстан Республикасының қор нарығының ағымдағы жағдайы талданды, негізгі мәселелер айқындалды және оның даму перспективалары қарастырылды. Зерттеу инвестициялық климатқа әсер ететін факторларға, нарықтың құрылымдық аспектілеріне және реттеуге бағытталған. Құбылмалылық, әртараптандырудың жоқтығы және ашықтықтың болмауы сияқты қиындықтарға ерекше назар аударылды. Осы мәселелер контекстінде инвестициялар тарту және экономикалық өсуді ынталандыру әлеуетін ескере отырып, Қазақстанның қор нарығын жақсарту бойынша ұсыныстар беріліп, мүмкіндіктері талқыланды. Жаһандық пандемия жағдайында Қазақстан қор биржасы (KASE) және әлемнің басқа да биржалары онлайн форматқа көшуге мәжбүр болды. Әр түрлі уақытта биржа қызметкерлерінің 80%-ға дейіні онлайн режимде жұмыс істегеніне қарамастан, биржалық нарықтың барлық қатысушылары үшін қызметтері мен инфрақұрылымдардың тұрақты қолжетімділігі қамтамасыз етілді. Алайда, Қазақстан қор биржасының өзіндік мәселелері мен бағалы қағаздарға сұраныс пен ұсыныс, сондай-ақ Қазақстанның қор нарығына инвестиция тарту мен капиталды қалыптастырудағы бұл құралдардың рөлі талданды. Бағалы қағаздар мен облигациялар саласындағы реттеуді одан әрі дамыту және жетілдіру бойынша ұсынымдар Қазақстан Республикасында қаржылық тұрақтылықты нығайту және қолайлы инвестициялық ортаны құру тұрғысынан талқыланды.
KEY SUCCESS FACTORS OF AN ERP SYSTEM IN HIGHER EDUCATION MANAGEMENT
Authors:   Astana IT University, Astana city, Kazakhstan, Nurgozhinov Z.E. , Salykova L.N. ,   Astana IT University, Astana city, Kazakhstan
Published: February 2024

В статье исследуются критические факторы успеха (CSF) при внедрении систем планирования ресурсов предприятия (ERP) в секторе высшего образования. Опираясь на результаты многочисленных исследований, он дает представление о ключевых факторах, определяющих успешное внедрение ERP. Исследование подчеркивает важность технических аспектов, таких как управление проектами и выбор ERP-системы. Вовлеченность пользователей, обучение и удовлетворенность также определены в качестве ключевых факторов. Более того, в статье подчеркивается важность решения культурных и организационных проблем, подчеркивается необходимость управления изменениями. Эффективная коммуникация, надежное планирование и поддержка руководства становятся необходимыми условиями для триумфа проекта ERP. Показано, что анализ данных и управление ими помогают принимать решения и повышать производительность. Также подчеркивается роль поддержки поставщиков и совместимости аппаратного и программного обеспечения. Выводы, изложенные в этой статье, являются ценным руководством для учебных заведений, стремящихся успешно внедрить ERP-системы в сфере высшего образования.
Flaws to Police investigative Practices in Pakistan
Authors: Iqbal Muhammad Ahsan , Saleem Hafiz Abdul Rehman , Baig Mahnoor , Hassan Zuntiqam-Ul-
Published: February 2024

A criminal investigation is a core aspect of a criminal trial. Unfortunately, Pakistani police are considered incompetent in public opinion. To understand the police's role in criminal investigation this research is conducted.   There are four aspects of this research, first aspect UN Investigation protocols will be discussed, secondly importance of Crime Scene Investigation, Problems of Criminal investigation supported by judges of Superior Courts in Pakistan and at the end we will try to fix the following problems. Which are, what Problems remained unaddressed in Criminal Investigation by Investigation Officer? How problems can be fixed by the Police Department and legislature to remove flaws in the investigation process? This research consists of secondary data.