bluuebunny/crossref_metadata_2025 huggingface dataset:
Seroprevalencia de COVID19 en personas viviendo con VIH en el Área Metropolitana de Buenos Aires.
Authors: Longueira Yesica , De la Fuente Florencia , Montesano Fernando , Salomon Horacio , Turk Gabriela , Quiroga María Florencia , Laufer Natalia
Published: November 2021

Se desconoce si las personas que viven con el VIH (PVV) tienen un mayor riesgo de contraer la infección por SARS-CoV-2. Los estudios serológicos prospectivos pueden permitir análisis de seroincidencia. Este estudio prospectivo incluyó a PVV, sin antecedentes de vacunación contra SARS-CoV-2, de la Ciudad Autónoma de Buenos Aires (CABA) y Gran Buenos Aires (GBA) que concurrieron entre marzo y junio de 2021 a realizar sus controles al Instituto INBIRS. La tasa de seroprevalencia de anticuerpos contra la proteína espiga del SARS-CoV-2 fue del 33.3% (IC 24.9-42.5%) para la población estudiada. Esta prevalencia fue significativamente mayor a la reportada previamente para la población general de la misma región geográfica.  No se observó una asociación entre el recuento de linfocitos T CD4+ con los niveles de IgG especifica. En conclusión, el hallazgo de una alta seroprevalencia de anticuerpos contra SARS-CoV-2 entre las PVV en CABA y GBA pueden sugerir una mayor susceptibilidad a la infección por este virus; sin embargo, puede ser también un marcador subrogante que la tasa de seroprevalencia en población general se encuentra subestimada.
Legionella pneumophila: un patógeno emergente en Argentina
Authors: Medina Marcelo Gabriel , Lösch Liliana Silvina , Merino Luis Antonio
Published: November 2021

Legionella, siendo la especie pneumophila el principal agente etiológico de esta patología. Esta bacteria se describió por primera vez en 1977 como causa de un brote de neumonía grave registrado en 1976 en un centro de convenciones en los Estados Unidos de América. La enfermedad se presenta como una neumonía atípica, responsable del 1 al 15 % de los casos de neumonías adquiridas en la comunidad (NAC), del 5 al 10% de neumonías del adulto y del 1% en menores de 15 años. Los miembros de la familia Legionellaceae son bacilos aeróbicos gramnegativos que crecen lentamente y se encuentran ampliamente distribuidos en cuerpos de agua. La forma más común de transmisión de Legionella spp es la inhalación de aerosoles contaminados generados a partir de fuentes de agua artificiales.  Se asocian con la aparición de brotes esporádicos y epidémicos en la comunidad y en infecciones nosocomiales. Las especies pertenecientes al género Legionella se consideran patógenos emergentes transmitidos por el agua. 

El objetivo de este trabajo es realizar una revisión sobre las manifestaciones y presentaciones clínicas de la infección causada por L. pneumophila, en virtud de que es considerado mundialmente un patógeno emergente y por existir evidencias de su presencia en sistemas de almacenamiento de agua tratada en la región Nordeste de la República Argentina, razón primordial para alertar y actualizar conocimientos al respecto.
ТЕНДЕНЦИИ РАЗВИТИЯ ТЕХНИКО-КРИМИНАЛИСТИЧЕСКИХ СРЕДСТВ ОБНАРУЖЕНИЯ, ФИКСАЦИИ, ИЗЪЯТИЯ И ИССЛЕДОВАНИЯ НАРКОТИКОВ
Authors: Сарсембаев Болат , Сейтхожин Булат
Published: November 2021

Мақалада есірткіні анықтау, бекіту, алу және зерттеудің техникалық құралдарын қысқаша талдау негізінде олардың даму тенденциялары мен болашағы көрсетіліп жылжымалы сот-криминалистикалық зертханаларда осы құралдарды қолдану нұсқалары қарастырылды

В статье на основе краткого анализа технических средств обнаружения, фиксации, изъятия и исследования наркотиков рассмотрены варианты применения этих средств в передвижных судебно-криминалистических лабораториях с указанием тенденций и перспектив их развития.

In the article, based on a brief analysis of technical means of detection, fixation, seizure and research of drugs, options for the use of these means in mobile forensic laboratories are considered, indicating trends and prospects for their development.
УПОТРЕБЛЕНИЕ, ВСТРЕЧАЮЩЕЕСЯ В ВИДЕ СЛОВОСОЧЕТАНИЯ В ОБРАЗЦАХ ЗАПИСИ
Authors: Баербекова Әлия , Бажикеев Құрмет
Published: November 2021

Аталмыш мақалада ХV-ХVІІ ғасырларда түркі халықтары тілдеріне енген араб, парсы сөздерінің түркі жазба ескерткіштерінде сөз тіркесі түрінде қолданылу мәселесі қарастырылады. Сонымен қатар, бұл кезеңдегі түркі жазба тілдеріне тән белгілердің бірі – халық тіліне енбеген, көбінесе дерексіз ұғым атаулары болып келетін араб және парсы сөздерін де актив қолдану, бұл ретте әсіресе, араб-парсы сөздерінің түркі тілінің көмекші етістіктерімен тіркесуі арқылы күрделі етістік жасап пайдалану өте көп кездеседі. Мақалада,Өтеміс қажының «Шыңғыснамасы», «Әділ сұлтан» эпикалық жыры, Қадырғали Жалайыридің «Жамиғат-Тауарихы» және Әбілғазы Бахадүр ханның «Түркі Шежіресі» атты шығармалары талданады. Түйінді сөздер: түркі халықтары, сөз тіркесі, тұрақты тіркестер, жазба ескерткіштер.

В данной статье рассматривается вопрос использования арабских и персидских слов, вошедших в языки тюркских народов в ХV-ХVІІ веках, в виде словосочетаний в тюркских письменных памятниках. Кроме того, одной из характерных особенностей тюркских письменных языков этого периода является активное употребление арабских и персидских слов, которые не вошли в народный язык, часто являются абстрактными понятиями, при этом особенно распространено использование сложных глаголов путем сочетания арабско–персидских слов с вспомогательными глаголами тюркского языка. В статье анализируются произведения отемиса кажы «Чингиснама», эпическая поэма «Адиль султан», «Жамигат-Тауарихи» Кадыргали Жалаири и «тюркская шежире» Абельгазы Бахадур хана.

This article discusses the use of Arabic and Persian words that entered the languages of the Turkic peoples in the XV-XVII centuries, in the form of phrases in the Turkic written monuments. In addition, one of the characteristic features of the Turkic written languages of this period is the active use of Arabic and Persian words, which are not included in the popular language, are often abstract concepts, and the use of complex verbs by combining Arabic – Persian words with auxiliary verbs of the Turkic language is especially common. The article analyzes the works of Otemis kazha "Genghisnam", the epic poem "Adil Sultan"," Zhamigat-Tauarihi "by Kadyrgali Zhalairi and "Turkic shezhire" by Abelgazy Bahadur Khan.
ЭКВИВАЛЕНТНЫЙ ПЕРЕВОД ЭВФЕМИЗМОВ В СОВРЕМЕННЫХ КАЗАХСКО-АНГЛИЙСКИХ ЯЗЫКАХ
Authors: TLENDIYEV A. , BEKKOZHANOVA G.
Published: November 2021

This article is written on researches about euphemisms in the English language, their classifications, the logic of origin and compared with Kazakh language euphemisms. Searching answers for questions like how to translate euphemisms from English to Kazakh and against. In the beginning, as a tradition, the article started with translation theory then smoothly changes to types of translation. Further, we discuss equivalent translation also talk a little bit about phraseology. Finally, the topic comes to the translation of euphemism. We consider what the euphemisms mean, how to translate, hоw they are formed, the problems of euphemisms, classifications and examples. The article sums up the research results.

Бұл мақала Ағылшын тіліндегі евфемизмдерді зерттеу барысында жазылып, олардың классификациялануы, жасалу жолы Қазақ тіліндегі эвфемизмдерімен салыстырылды. Эвфемизмдерді Ағылшын тілінен Қазақ тіліне және керісінше қалай аудару керек деген сұрақтарға жауап іздестіріп көрдік. Бастапқы бөлігінде, дәстүрге сай аударма теориясы туралы сөз қозғалды, ары қарай бірте-бірте аударма түрлері, баламалылық аударма туралы айтылып, аздап фразеологияны тілге тиек еттік. Аяқ жағына қарай тақырыптың өзегі болған эвфемизм туралы айтып өттік. Нақтылап айтқанда, эвфемизмдердің мағынасы қалай аударылатындығы, қалай жасалатындығы, эфвемизмдегі аударма мәселелері, классификациясы мен мысалдары берілген. Мақалада тақырып бойынша қорытынды жасалды.

Данная статья об эвфемизмах в английском языке и их классифициях, про методы строения и сопоставлялась с эвфемизмами в казахском языке. А так же, мы искали ответы о том, как перевести эвфемизмы с английского языка на казахский и обратно. В начальной части по традиции статья начинается с теории перевода эвфемизмов. Затем мы переходим на основные виды перевода эвфемизмов. Мы расматривали темы эквивалентного перевода, а также упомянуто про перевода фразеологизмов. К концу мы расмотрели главную тему про эвфемизмов, а точнее их значение, как перевести, как они формируются, проблемы эвфемизма, классификация и примеры. Статья выводит итоги проделанной работы по теме статьи.
ABOUT THE RESULTS OF SCIENTIFIC RESEARCH IN THE FIELD OF ENSURING THE SAFETY OF MOTOR TRANSPORT
Authors: Бакишев Кайрат
Published: November 2021

В статье автор подводит итоги трехлетнего (2018-2020) научного исследования на тему: «Организационные и прикладные проблемы обеспечения безопасности дорожного движения в Республике Казахстан», проведенного по заказу Комитета науки МОН РК. Подчеркивается актуальность, теоретическая и практическая значимость исследования, указываются цель и способы, которые были использованы для его достижения, а также результаты, которые легли в основу разработанной Концепции обеспечения безопасности дорожного движения в Казахстане на ближайшее десятилетие. В статье подчеркивается, что причинами дорожных аварий с жертвами являются, прежде всего, социально-экономические, организационные, правовые, технические, нравственные и другие факторы, определяемые интенсификацией научно-технического прогресса. Поэтому профилактика ДТП и автотранспортных правонарушений должна осуществляться на основе долгосрочных комплексных программ на региональном и республиканских уровнях.

Мақалада автор ҚР БҒМ Ғылым комитетінің тапсырысы бойынша жүргізілген "Қазақстан Республикасында жол қозғалысы қауіпсіздігін қамтамасыз етудің ұйымдастырушылық және қолданбалы мәселелері" тақырыбындағы үш жылдық (2018-2020) ғылыми зерттеудің қорытындысын шығарады. Зерттеудің өзектілігі, теориялық және практикалық маңыздылығы атап көрсетіледі, оған қол жеткізу үшін пайдаланылған мақсат пен тәсілдер, сондай-ақ таяудағы онжылдықта Қазақстанда жол жүрісі қауіпсіздігін қамтамасыз етудің әзірленген тұжырымдамасының негізіне алынған нәтижелер көрсетіледі. Мақалада құрбандармен жол апаттарының себептері, ең алдымен, ғылыми-техникалық прогресті қарқындатумен анықталатын әлеуметтік-экономикалық, ұйымдастырушылық, құқықтық, техникалық, адамгершілік және басқа факторлар болып табылады. Сондықтан жол-көлік оқиғалары мен автокөлік құқық бұзушылықтарының алдын алу аймақтық және республикалық деңгейдегі ұзақ мерзімді кешенді бағдарламалар негізінде жүзеге асырылуы тиіс.

In the article, the author summarizes the results of the three-year (2018-2020) scientific study on the topic: "Organizational and applied problems of road safety in the Republic of Kazakhstan", conducted by order of the Committee of Science of the Ministry of Education and Science of the Republic of Kazakhstan. The relevance, theoretical and practical significance of the research is emphasized, the purpose and methods that were used to achieve it are indicated, as well as the results that formed the basis of the developed Concept of Road Safety in Kazakhstan for the next decade. The article points out that the causes of road accidents with victims are, first of all, socio-economic, organizational, legal, technical, moral and other factors determined by the intensification of scientific and technological progress. Therefore, the prevention of road accidents and motor vehicle offences should be based on long-term comprehensive programs implemented at the regional and national levels.
Technological Remedy for Music Practical Lessons Amidst Covid-19 Restrictions in the Department of Music Education, University of Education Winneba
Authors: S.N. Ayensu , E.O. Acquah , J.F. Annan
Published: November 2021

The Department of Music Education, University of Education Winneba (UEW), trains students to acquire the skill of playing some Western instruments such as the keyboard, guitar, winds and orchestral strings. Furthermore, students also receive training in playing Ghanaian traditional instruments such as the atenteben and the various traditional drums of the existing ensembles. This practical teaching also include singing, dancing and ensemble making to allow all students perform their instruments in an ensemble. Unexpectedly, training in these instruments and ensembles was despaired by measures to contain the spread of Covid-19 pandemic. While theory courses in music were conducted via platforms such as Moodle, Google Classroom, the University’s Virtual Class (VClass) and Zoom, the exploratory case study design was used to seek technological means to conduct practical lessons which almost came to a halt as a result of its face-to-face teaching nature. Reviewing literature on technologies for teaching and Covid-19, the study which was based on Technological Pedagogical Content Knowledge (T-PACK) model unearthed means to conduct practical lessons. Lecturers, instructors, technicians and students of the Department were interviewed to organize their opinions on how to conduct practical lessons amidst Covid-19 restrictions. The study divulged innovative technological means to situate software programmes and applications such as Zoom, Google Classroom, Moodle, Microsoft Meet, Team Viewer, WhatsApp and Facebook for practical lessons.
Development of a Cassava Harvester
Authors: O.D. Isinkaye , O.O. Koyenikan , T. Osadare
Published: November 2021

Cassava is a major source of food and raw material for domestic and industrial uses in Nigeria. Consequently, the technologies involved in its cultivation from planting to harvesting require proper development. This paper reports the development of a labour-saving technology for harvesting cassava using standard procedures for designing soil engaging implements. Locally available materials were also used in the fabrication of the harvester. Results of trial tests indicate a digging efficiency of 58.9%, fuel consumption of 16 l/ha, field capacity of 0.11 ha/hr, field efficiency of 67.9% and root damage of 43.03%. The total cost of fabricating the machine was 184,000 naira only. Further tests under various soil and operational conditions for improvement and optimization were recommended for the purpose of patenting for commercialization.
Melphalan flufenamide is an Anticancer medication used to treat multiple Myeloma: A Review
Authors: Jain Mayur S. , Bhurat Mayur R. , Bavaskar Sunil R
Published: November 2021

Melphalan Flufenamide is a peptide-drug conjugate composed of a peptide conjugated, via an aminopeptidase-targeting linkage, to the alkylating agent melphalan, with potential antineoplastic and anti-angiogenic activities. Upon administration, the highly lipophilic melphalan flufenamide penetrates cell membranes and enters cells. In aminopeptidase-positive tumor cells, melphalan flufenamide is hydrolyzed by peptidases to release the hydrophilic alkylating agent melphalan. This results in the specific release and accumulation of melphalan in aminopeptidase-positive tumor cells. Melphalan alkylates DNA at the N7 position of guanine residues and induces DNA intra- and inter-strand cross-linkages. This results in the inhibition of DNA and RNA synthesis and the induction of apoptosis, thereby inhibiting tumor cell proliferation. Peptidases are overexpressed by certain cancer cells. The administration of melphalan flufenamide allows for enhanced efficacy and reduced toxicity compared to melphalan.1,2,3
Floating Drug Delivery System: An Overview
Authors: Bindu A.V.S. Hima , Bhavya G. , Padmalatha K.
Published: November 2021

In recent years scientific and technological advancements have been made in the research and development of rate-controlled oral drug delivery systems by overcoming physiological adversities, such as short gastric residence times (GRT) and unpredictable gastric emptying times (GET). Several approaches are currently utilized in the prolongation of the GRT, including floating drug delivery systems (FDDS), also known as hydrodynamically balanced systems (HBS), swelling and expanding systems, polymeric bioadhesive systems, modified-shape systems, high-density systems, and other delayed gastric emptying devices. The different strategies used in the development of FDDS by constructing the effervescent and noneffervescent type of floating tablets basis of which is buoyancy mechanism. FDDS is a method to deliver the drugs that are active locally with a narrow absorption window in the upper gastrointestinal tract, unstable in the lower intestinal environment, and possess low solubility with higher pH values. The recent developments in floating drug delivery systems are containing the physiological and formulation variables impacting on gastric retention time, approaches to formulating of single-unit and multiple-unit floating systems, and their classification and formulation aspects are discussed in detail. This review also summarizes evaluation parameters and application of floating drug delivery systems.
Review on Mucormycosis: It is a life Threatening infection
Authors: Mankar S.D. , Poonam Waditake , Jejurkar Prajakta
Published: November 2021

Mucormycosis, often known as black fungus, is a fungal infection caused by the mucormycetes fungi. Zygomycetes is a class of fungi. Mucormycetes, the fungus that cause mucormycosis, are found all throughout the world, especially in soil and in decaying organic waste like leaves, compost piles, and animal dung. It is not contagious and cannot be passed from one person to another. Mucormycosis (also known as zygomycosis) is a dangerous but uncommon fungal infection caused by a fungus known as mucormycetes. Molds can be found all over the place. Mucormycosis is a fungal infection that primarily affects persons who have health issues or who use medications that reduce the body's capacity to resist infections and illness. Infections are most typically acquired when mould spores are inhaled or, less commonly, when spores enter the body through a cut in the skin. It takes place after COVID-19. Home remedies, such as consuming probiotics, and foods that promote immunity, can help to minimise mucormycosis. The main purpose of this review Related to Mucormycosis is to diminish the growth of Mucormycosis by taking Ayurvedic Treatment.
Synthesis and Characterization of calcium Starch: A New Controlled Release Polymer for floating tablets of Losartan Potassium
Authors: Prathyusha K. Naga , Hemalatha B. , Padmalatha K.
Published: November 2021

Losartan potassium is used to treat high blood pressure (hypertension). The present study was aimed to prepare a floating drug delivery system to design a controlled release oral dosage form of Losartan potassium. This helps to overcome the demerit of limited residence time of the drug in the gastrointestinal track and hence to increase the duration of release. Hence objective of the present study is to develop Losartan potassium floating tablets by direct compression method using calcium starch as release retarding polymer. The calcium starch was synthesized by gelatinizing potato starch in the presence of sodium hydroxide and cross linking by treatment with calcium chloride. The micromeritic properties studies indicated that calcium starch is a promising pharmaceutical excipient in tablets. Floating tablets of Losartan potassium was formulated by direct compression technique, using different concentration of calcium starch and compared with HPMC K-100 as release retard polymer. As the amount of calcium starch in the tablet increased, the drug release decreased. The formulation F5 containing 125 mg calcium starch showed better controlled release of 76.38% after 12 hours.
Formulation and Evaluation of Solid Self Nano Emulsifying drug delivery System of Olanzapine to Enhance Aqueous Solubility and Dissolution Rate
Authors: Reddy M. Sunitha , Sravani Baskarla
Published: November 2021

Present research work was aimed to enhance aqueous solubility and dissolution rate of olanzapine by solid self nano emulsifying drug delivery system(S-SNEDDS). Olanzapine is a BCS class II drug having 65% oral bioavailability; it is used in the treatment of psychosis, depression and mania conditions. Oils, Surfactants, Co surfactants were selected depending upon the saturated solubility of olanzapine in those components; excipients were screened depending on olanzapine solubility in various oils, surfactants and co surfactants. Surfactant: co surfactant {Smix} ratios i.e., 3:1 and 4:1 were prepared to determine nano emulsion regions and also to formulate liquid self nano emulsifying drug delivery system (L-SNEDDS). Pseudo ternary phase diagram were plotted by using Triplot version 4.1.2 software, nano emulsion region was determined and evaluated. Formulations were designed based on saturated solubility of olanzapine and Pseudo ternary phase diagram using various ratios of oils [Capryol 90], surfactants [Kolliphor EL], co surfactants [Lauroglycol 90] depending on its solubility and nano emulsion formation four formulations were developed which are further selected for characterisation of L-SNEDDS like robustness to dilution, self emulsification, determination of droplet size, PDI, Drug loading efficacy, zeta potential and also Invitro drug release. Among those four formulations, F1 (SB184J 4:6) was optimum because compared to other three formulations F3 gave best results in terms of droplet size (66nm) with PDI (0.24), Invitro drug release, dissolution rate of F1 SNEDDS having (88.201± 0.25%). Invitro drug release of F1 formulation was compared with that of Olanzapine [API] (45.281± 0.52%) the results indicating that there is a increase in solubility and dissolution rate of olanzapine by 2.2 times more compared to pure olanzapine (API). F1 (SB184J 4:6) were converted into S-SNEDDS by adsorption process by addition porous carriers (Aerosil 200). Formulated S-SNEDDS were undergone various evaluation parameters and also reconstitution parameters to determine Droplet size and Invitro drug release of solid F1 (SB184J4:6) formulation. The results of present study demonstrates that olanzapine SNEDDS has an ability and potential to enhance solubility and dissolution rate.
A Review on Covid 19 Pandemic and its Global Effects
Authors: Vishnu Kandra Naga , Kumar Uppala Praveen , Vangoori Yakaiah , Rao Gudhanti Siva Naga Koteswara
Published: November 2021

The novel Corona Virus Disease popularly known as COVID-19 brought all sectors to a temporary standstill since its first outbreak in Wuhan China in 2019. The rapid spread of this disease to all countries of the world made it to be declared a pandemic by the world health organization in the first quarter of the year 2020. This pandemic exposed the world population to the understanding of immunity since that was the only remedy at present to this new pandemic. The morbidity and mortality of this new virus were estimated across the globe by many institutions and organizations. The tropical regions where malaria epidemic is more pronounced is less affected by COVID-19 probably due to high immunity already developed by the population as a result of frequent malaria disease and regular use of anti-malarial drug.
A systematic Review of Aloe vera and its Properties
Authors: Fatma Farha , Kumar Anil
Published: November 2021

Aloe vera is one of the oldest medicinal plant ever known, commonly known as Ghrit Kumari. It is well known for its therapeutic potential. Some of its beneficial effects include anticancer, hypoglycemic, antifungal, anti-inflammatory, burn healing properties. Phytochemistry of Aloe vera gel has revealed presence of bioactive chemicals. In this review paper, properties of Aloe vera, its composition, its beneficial effects and pharmaceutical uses, its application in foods and cosmetics etc. have been summarized.
Emulgel: A Review
Authors: Hasan Sahil , Bhandari Saloni , Sharma Anshu , Garg Poonam
Published: November 2021

Emulgel systems are currently attention to the pharmaceutical sectors because of their substantial potential to act as drug delivery vehicle by incorporating a broad range of drug molecules and higher stability compared to the other dosage form like cream, lotion, gel, etc. Emulsions are either available in an oil in water or water in oil type. These are prepared by the incorporation of the emulsion into the gel with constant stirring at a moderate speed. Incorporation of emulsion into a gel makes it a dual control release system, thereby, increasing its stability. It has better drug release if we compare to other topical drug delivery system. It is non greasy because of the presence of gel phase which enhances patient compliance. Gels has a major limitation for the delivery of hydrophobic drugs, so to overcome this limitation an emulsion based approach is being used so that even a hydrophobic therapeutic drug can enjoy the unique properties of gels. In recent years, these have also been a great interest in the use of novel polymers. These emulgels are having major advantages on vesicular drug delivery systems as well as on conventional systems in various aspects. Various permeation enhancers can enhance the effect; due to this emulgels can be used as better topical drug delivery systems over current drug delivery systems. The emulsion can be use for analgesics and antifungal drugs.
Formulation and Evaluation of Orodispersible Tablet of poorly water Soluble Drug ‘Fenofibrate’ by Using Solubility Enhancement Technique
Authors: Dabeer Ali Asgar , Kumar Mishra Dinesh , Farooqui Nadeem , Gawshinde Arpit
Published: November 2021

In the recent years scientific and technological advancements have been made in the research and development of oral drug delivery systems. The aim of this study was to formulate and evaluate of orodispersible tablets by direct compression for fenofibrate by using super fast disintegrating agents like croscarmellose sodium. The use of super disintegrant and excipient for preparation of fast disintegrating is highly effective and commercially feasible. In the present investigation poorly water soluble drug is one of the most important parameters of oral formulations sucessfully developed fenofibrate was using solvent evaporation method drug: PEG 6000 in (1:5 w/w). The formulation F7 was the optimized formula that showed satisfactory results with various physicochemical evaluation parameters like thickness, hardness, weight variation, friability, drug content, % drug release almost 79.98% within 15 min. and it was follow the maximum higuchi release kinetics that regression coefficient values ‘r2’= 0.995.
Formulation and Evaluation of Polyherbal Antiaging Cream
Authors: Yadav Aman , Kumar Mishra Dinesh , Paliwal Pritesh , Farooqui Nadeem , Gawshinde Arpit
Published: November 2021

Moringa oleifera family Moringaceae and Ocimum sanctum family Labiatae has been reported to possess antioxidant, antimicrobial, antiinflammatory, antibacterial and antifungal properties. Moringa oleifera and Ocimum sanctum extracts have been used to treat antimicrobial infections. The aim of this present study is to formulate and evaluate of polyherbal anti-aging cream by combining the extract of Moringa oleifera with Ocimum sanctum to achieve multipurpose skin effects such as anti-aging, fairness, softening and antiseptic effects.The polyherbal anti-aging cream formulations comprising of hydroalcoholic extract of Moringa oleifera and Ocimum sanctum, carbapol 940, xanthan gum, stearic acid, glycerol monostearate and cetyl alcohol were prepared and evaluated for physicochemical parameters and the results showed the production of stable polyherbal anti-aging cream. The formulated polyherbal anti-aging cream (O/W) was subjected to characterize like visual inspection, pH, viscosity, good spreadability, good consistency, homogeneity, no evidence of phase separation and ease to washable from skin. Formulation (F4) exhibited fulfilled the objectives of the current research and % drug release is 98.78 and exhibit good anti-microbial activity.
Nanotechnology: Overview and its application
Authors: Nikam Amit , Patil Anuja , Magdum Chandrakant
Published: November 2021

The study of different microscopic or tiny shaped and sized particles is what nanotechnology is all about. These nano-structured compounds have a wide range of strong actions in a variety of disciplines. These are readily carried due to their small size and form. Because of its small size, it may be used in a variety of ways. Nanotechnology improves a variety of businesses, including the pharmaceutical industry, the food industry, environmental protection, and a variety of others. The purpose of this article is to provide an overview of nanotechnology and its applications in different industries and areas.
Sử dụng mô hình Logit của hệ thống cảnh báo sớm để dự báo khủng hoảng tiền tệ tại Việt Nam
Authors: Phạm Thế Hiển
Published: November 2021

Việt Nam là một trong những nền kinh tế của khu vực Đông Nam Á đã tránh được suy thoái từ các cuộc khủng hoảng tiền tệ xảy ra trước đây. Với mục đích có thể giám sát và duy trì sự phát triển ổn định, bền vững của hệ thống tài chính vĩ mô, bài viết tham khảo một số nghiên cứu trong và ngoài nước, tiếp tục ứng dụng mô hình xác suất Logit để ứng dụng trong dự báo khủng hoảng tiền tệ ở Việt Nam. Nghiên cứu sẽ lựa chọn các chỉ số dự báo phù hợp cho Việt Nam trong giai đoạn từ tháng 01/2008 đến tháng 12/2016. Cuối cùng, là đưa ra một số hàm ý về chính sách cũng như nâng cao chất lượng cho mô hình dự báo khủng hoảng tiền tệ tại Việt Nam cho các nghiên cứu tiếp theo.
Dạng giải tích gần đúng sóng dài của tần số plasmon trong cấu trúc BLG - GaAs
Authors: Nguyễn Văn Mện , Đồng Thị Kim Phượng
Published: November 2021

Các kết quả giải tích cho phổ plasmon của vật liệu còn rất hạn chế do tính phức tạp của hàm phân cực. Bài báo này trình bày biểu thức giải tích của tần số plasmon trong gần đúng sóng dài của một cấu trúc lớp đôi được tạo thành từ một lớp bilayer graphene và giếng thế lượng tử GaAs. Các tính toán có kể đến bề dày lớp khí điện tử và sự không đồng nhất của hằng số điện môi nền dựa trên các hàm phân cực trong gần đúng pha ngẫu nhiên. Kết quả cho thấy, tần số nhánh quang học có dạng giống với biểu thức đã được đề cập trong các công trình trước đây, trong khi tần số nhánh âm học chịu ảnh hưởng của cả khoảng cách giữa hai lớp và bề dày lớp.
Tình trạng dinh dưỡng và một số yếu tố liên quan của bệnh nhân gút tại Bệnh viện Đa khoa Xanh pôn năm 2020 - 2021
Authors: Tiến Nguyễn Thành , Phan Thị Bích Hạnh , Nguyễn Ngọc Thu , Nguyễn Thị Hương Lan , Ninh Nguyễn Thuỳ
Published: November 2021

Nghiên cứu nhằm mô tả tình trạng dinh dưỡng và một số yếu tố liên quan đến tình trạng dinh dưỡng của bệnh nhân gút tại Bệnh viện Đa khoa Xanh Pôn. Nghiên cứu mô tả cắt ngang thực hiện trên 73 đối tượng trên 18 tuổi được chấn đoán mắc bệnh gút theo tiêu chuẩn ACR/EULAR 2015 (Hội Thấp khớp học Hoa Kì và Liên đoàn phòng chống thấp khớp Châu Âu), trong thời gian từ tháng 12 năm 2020 đến tháng 3 năm 2021. Kết quả nghiên cứu cho thấy có 5,5% bệnh nhân có tình trạng thiếu năng lượng trường diễn (BMI - chỉ số khối cơ thể < 18,5), 53,4% bệnh nhân có tình trạng thừa cân/béo phì (BMI ≥ 23). Những đối tượng mắc bệnh mạn tính không lây đi kèm có nguy cơ thừa cân/béo phì cao hơn so với những đối tượng không mắc bệnh (OR = 7,4). Khi đánh giá theo phương pháp SGA, có 15,0% người bệnh có nguy cơ suy dinh dưỡng ở mức độ nhẹ đến vừa (SGA-B), trong đó bệnh nhân nội trú chiếm tỉ lệ cao hơn so với bệnh nhân ngoại trú (31,6% so với 9,3%). Những người bệnh có trên 10 đợt gút cấp/năm có nguy cơ suy dinh dưỡng lớn hơn (OR = 5,6), theo phương pháp SGA.
Tình trạng dinh dưỡng và khẩu phần 24h của người bệnh viêm gan mạn tại Bệnh viện Bệnh nhiệt đới Trung ương năm 2020-2021
Authors: Trang Ngô Quỳnh , Phú Phạm Văn
Published: November 2021

Hiện nay viêm gan B và C mạn đã và đang là vấn đề sức khỏe cộng đồng rất lớn ở nước ta cũng như thế giới. Tỷ lệ suy dinh dưỡng (SDD) ở người bệnh mắc bệnh gan mạn có thể từ 65-90% theo các phương pháp đánh giá khác nhau. Người bệnh thường bị giảm khẩu phần ăn do nhiều nguyên nhân. Nghiên cứu mô tả cắt ngang được thực hiện nhằm đánh giá tình trạng dinh dưỡng (TTDD) và khẩu phẩn 24h của 166 người bệnh mắc bệnh viêm gan B,C mạn tại Khoa viêm gan - Bệnh viện Bệnh nhiệt đới trung ương. Kết quả cho thấy tỷ lệ suy dinh dưỡng theo SGA là 38,6%. Nhóm người bệnh cao tuổi (≥ 65 tuổi) có tỷ lệ suy dinh dưỡng cao hơn so với nhóm người bệnh < 65 tuổi (57,1% và 33,6%). Nhóm người bệnh xơ gan (XG) mất bù có tỷ lệ suy dinh dưỡng cao nhất, sau đó là nhóm XG còn bù và thấp nhấp là nhóm chưa bị XG (56,2%; 38,2% và 22%). Tình trạng dinh dưỡng có liên quan đến tuổi và mức độ xơ gan (p < 0,05). Giá trị trung bình năng lượng khẩu phần của đối tượng nghiên cứu (ĐTNC) là 1129,7 ± 481,1 kcal/ngày. Lượng protein đạt 0,8 ± 0,4 g/kg/ngày. Phần lớn người bệnh  không đạt nhu cầu khuyến nghị (NCKN) về năng lượng, protein và nhiều vi chất (vitamin A, D, B1, B2, PP, kẽm, magie, sắt, canxi, phospho).
Hiệu quả của dung dịch Maltodextrin 12,5% đường uống 2 - 4 giờ trước phẫu thuật cắt túi mật nội soi
Authors: Vũ Hoàng Oanh , Phượng Dương Thị , Lê Thị Hương
Published: November 2021

TÓM TẮT:
Nhịn đói qua đêm trước phẫu thuật nhằm tránh biến chứng hít sặc phổi, tuy nhiên gây ra khó chịu cho người bệnh. Hiệp hội Tăng Cường Phục Hồi Sau Phẫu Thuật (ERAS) và Hiệp Hội Gây Mê Châu Âu (ESA) đã khẳng định sử dụng carbohydrate đường uống trước phẫu thuật 2 giờ là an toàn và cải thiện cảm giác khó chịu liên quan phẫu thuật của người bệnh. Chúng tôi tiến hành thử nghiệm lâm sàng ngẫu nhiên có đối chứng trên 40 bệnh nhân phẫu thuật cắt túi mật nội soi. Nhóm can thiệp được uống 200ml dung dịch maltodextrin 12,5% trước phẫu thuật 2 - 4 giờ. Nhóm chứng nhịn ăn uống từ 22 giờ ngày hôm trước phẫu thuật. Đánh giá tỉ lệ hít sặc phổi, thể dịch dịch tồn dư dạ dày trước phẫu thuật, cảm giác đói, khát, khô miệng, đau tại các thời điểm: lúc nhập viện, trước phẫu thuật, sau phẫu thuật. Nghiên cứu cho thấy không có trường hợp hít sặc phổi nào, thể tích dịch tồn dư dạ dày giữa 2 nhóm không có sự khác biệt có ý nghĩa thống kê (p = 0,1682). Giá trị trung bình điểm đói, khát, khô miệng trước phẫu thuật ở nhóm can thiệp thấp hơn có ý nghĩa thống kê so với nhóm chứng (p < 0,01). Điểm cảm giác đói, khát, khô miệng, đau sau phẫu thuật ở nhóm can thiệp thấp hơn nhóm chứng không có ý nghĩa thống kê (p > 0,05). Kết luận: Bổ sung 200ml dung dịch maltodextrin 12,5 % đường uống 2 - 4 giờ trước phẫu thuật cắt túi mật nội soi là an toàn và giúp cải thiện cảm giác đói, khát, khô miệng trước phẫu thuật.
SWOT Analysis of a Didactic Program in Dietetics: Results from Focus Group Research
Authors: Edens David , Burns-Whitmore Bonny
Published: November 2021

This study utilized focus group research to understand the experiences of students in a Didactic Program in Dietetics (DPD) at a large, public university. Students participating in the focus group reflected on and discussed the strengths, weakness, opportunities, and threats of the program. The participants stated that faculty support, hands-on learning, and opportunities to participate in clubs were strengths of the program. Students would like more opportunity to do research with faculty. They also indicated that there are program weaknesses such as access to common space, limits in course availability, roadblocks in curriculum, and limited access to necessary tools. Program opportunities, such as the upcoming accreditation visit, will express the student’s concerns and therefore focus administration’s attention on much needed financial support for the program. Although not a specific threat, changes in the credentialing for Registered Dietitian Nutritionists were also discussed by the students. Data were collected in preparation for an accreditation visit. However, the results can be used to advise department and university administrators about what items make students successful in their programs.
Purpose Driven Internet Use and Its Impact on Academic Performance of College Students
Authors: Waweru Aida W. , Gichugu Martin
Published: November 2021

The purpose of this study was to determine how students in Middle-Level Colleges use the internet, with a special focus on the Nairobi Institute of Business Studies (NIBS). The study was conducted using a descriptive research approach. The student population was determined using a purposive sample strategy, while the stratified sampling approach was utilized to divide the population into distinct subgroups (strata) based on the eight courses that students took. Both open-ended and closed-ended questionnaires were used to collect relevant data. The questionnaire was tested for validity and reliability in a group of randomly selected students. Following data collection, descriptive statistics were used to examine pertinent data. To summarize the data and report the research findings, descriptive statistics such as percentages, frequencies, bar graphs, and pie charts were used. This research focused on the NIBS College, which has approximately 3000 regular students. A total of 138 people were sampled from the population to participate in the study. The majority of students, according to the report, use the internet for entertainment. For communication and pleasure, students utilize social networking sites like Facebook and Twitter at nearly the same rates. The respondents also stated that using the internet has expanded their access to more up-to-date educational information and has had a good impact on their academic efficiency. When compared to traditional materials, respondents found the Internet to be more informative. The respondents also said that the internet saved time and provided reliable information. To access the internet, most students possess and use smartphones (iPhones). They use the internet in their dorms compared to other locations on campus or at home, where internet access was unreliable. The majority of students preferred Google to other Internet services. This demonstrated that students rely extensively on Google to find current and relevant information. The vast majority believed that people do not need to be trained on how to use the internet to find information. The trial-and-error method was the most prevalent strategy for obtaining relevant Internet skills. Others sought advice from their peers or took official training given by several computer colleges to learn how to utilize the internet.
Asistencia y apoyo en red a la familia por parte del estado, desde los servicios y programas para el ejercicio positivo de la parentalidad
Authors: Hernández Murillo Margarita
Published: November 2021

La convención de los derechos del niño declara que para que él niño se desarrolle, es relevante un clima de amor, felicidad y comprensión dentro de la familia; esta debe disfrutar de la asistencia y apoyo por parte del estado, para asumir sus responsabilidades y llevar a cabo la parentalidad con apoyos formales e informales, por lo que recibir soporte de profesionales de diversas áreas y servicios es de gran relevancia. La promoción de la educación parental es un instrumento del derecho a los servicios sociales y prestaciones básicas, ya que, buscan su integración en la comunidad como forma de potenciar o restablecer las redes de apoyo. Las redes de Atención en Salud son un gran apoyo para promover el ejercicio de la parentalidad, puesto que son ellos quienes mantienen contacto directo con las familias durante la gestación, el parto, puerperio y el seguimiento de la salud infantil y adolescente, acompañados por los servicios sociales.
Unidades educativo-terapéuticas intensivas: proteger el apego y el vínculo madre-bebé ante el desamparo en la perinatalidad
Authors: Aseguinolaza Chopitea Asier
Published: November 2021

Este artículo pretende revisar conceptos y justificaciones utilizados para la toma de decisión de decretar un estado de desamparo en un niño/a o adolescente. Partiendo del instrumento creado y utilizado para la valoración de la desprotección infantil, se pretende hacer una reflexión del periodo perinatal y las circunstancias generadas por la enfermedad mental perinatal. Se intenta poner en énfasis la protección del vínculo maternofilial y la necesidad de crear recursos especializados de atención a las madres e hijos que viven circunscritos en la enfermedad mental perinatal.
Prevención de la psicopatología perinatal durante la gestación
Authors: Ilieva Kovacheva Katina
Published: November 2021

En los últimos años, el conocimiento y las investigaciones en torno a la psicología perinatal han crecido exponencialmente, mostrando que el estado mental de la madre tiene importantísimas implicaciones en el desarrollo emocional, cognitivo y vincular del bebé, pero también en la pareja y la unidad familiar. La gestación no supone un estado protector para la salud mental. La mujer es más vulnerable al estrés y el puerperio es un período de especial incidencia de aparición de patología psíquica. Sin embargo, siguen existiendo pocos recursos asistenciales en salud mental perinatal. Generalmente las pacientes no piden ayuda y tratan de no manifestar sus problemas emocionales, por lo que solo se diagnostican una minoría de casos. En este artículo se pretende abordar la importancia de la salud mental de las mujeres embarazadas. Se hará un breve recorrido sobre los trastornos psicológicos que con mayor frecuencia se pueden encontrar en la etapa perinatal y los factores de riesgo más determinantes. También se repasarán algunos programas existentes para su prevención, detección o intervención.
Procesos de atención social a familias y menores en situaciones desamparo y/o tutela
Authors: Coll Espinosa Francisco Jesús
Published: November 2021

En este artículo vamos a exponer la situación de los/las menores y sus familias cuando se produce una situación de riesgo o desamparo y los procedimientos que se adoptan para paliar esas situaciones. En general, estas familias proceden de colectivos de «exclusión social» y describimos los aspectos más relevantes para conceptualizar los procesos de exclusión. Señalamos también los aspectos más relevantes de las leyes de protección a la infancia y los principios rectores que marcan su desarrollo.
Effects of Normal and Aberrant Glycosylation on the Stability of α1-Anti Trypsin Through Molecular Dynamic Simulation
Authors: Alam Khan Mujeeb , . Ehtesham , Shoaib Muhammad , Ali Roshan , Idrees Muhammad
Published: November 2021

The Alpha-1 antitrypsin belonging to serpin family is a protease inhibitor, the level of which rises by a factor of ten during inflammation Purpose: To investigate the stability of normal and aberrantly glycosylated α1-antitrypsin through molecular dynamics simulation Study Design: Experimental study Methodology: Current project was conducted in the department of Biochemistry at Institute of Basic Medical Sciences Khyber Medical University, Peshawar. A1AT FASTA sequence was retrieved from UniProt database (UniProt ID: P01009). Post-Translational Modifications (PTM) regions were identified from the same database. GLYCONNECT database was used to understand N-linked glycation with the asparagine residues found at position 70, 107, and 271 amino acid residue regions Statistical analysis: Different bioinformatics analyses such that Root Mean Square Deviation, Radius of gyration, Root Mean Square fluctuation, Hydrogen-bonding, Secondary Structure Determination, and Principal Component Analysis were executed for 100 ns molecular dynamics simulation run Results: RMSd, RMSf, and Rgyr significantly differ between the native type and cancer isoform. More H-bonding and strong protein stability and folding were seen in the native type. PCA analysis further confirms native type compact motion in the parallel direction during MD simulation Conclusion: It was concluded that glycated protein appears to have high structural stability than its aberrant glycated protein. However, it will be utilized for the prompt production of the anti-cancer drugs to effectively treating cancer disease Key Words: Alpha-1 Antitrypsin, Aberrant Glycosylation and Molecular Dynamic Simulation.
Presence of Affirmable Drug Affiliated Interactions in Medical Patients in Medical OPD of Pakistani Hospital
Authors: Ahmed Butt Hammad , Anwar Muhammad Zeeshan , Shahzad Akram , Iqbal Farah , Seemab Zafra , Abbas Saima , Laique Talha
Published: November 2021

Drug-drug interactions (DDIs), are preventable medical related hazards having grave life menacing and unfavorable consequences Purpose: To find the clinical adverse effects and interaction frequency witnessed in prescriptions of a medical OPD Study Design: Comparative study Methodology: A sample of 546 patients who were being prescribed at least two drugs simultaneously was assessed using a drug interaction program Statistical analysis: SPSS v.20.0 was used to analyze the data to present results as proportions Results: The 546 patients (72.8% male having mean age of 58.3±14.7 years. Out of these 186 (4.7%), 2595 (65.6%) and 773 (19.5%) were severe, moderate and mild interactions respectively Conclusions: We concluded that large percentage of patients were detected having one or more potential drug-drug interactions Keywords: Adverse Drug Interaction, Drug-Related Problems, Drug-Drug Interaction and Pharmaco-epidemiology.
Leisure Evaluation Behaviors and Attitudes of Students of Kilis 7 Semptember University
Authors: Güven Faruk , Çevik Ali , Yilgin Ahmet
Published: November 2021

The aim of the research is to examine the leisure management, attitudes and behaviors of the students studying at Kilis 7 September University. With the study, determining the current attitudes and behaviors of the students, Creating resources for the relevant units at the national and international level, especially the province of Kilis and Kilis 7 September University, reveals the importance of the research. Age, gender, marital status, class, academic units and leisure activity days per week of 387 students participating in the study were examined in order to determine their leisure management. According to the age variable, It was understood that 220 students aged 18-20 (56.8%) , 148 students aged 21-23 (38.2%), 12 students aged 24-25 (3.1%), and 7 students aged 26 and over(1.8%) were participated in the study. It was understood that there were 222 women (57.4%) and 165 men (42.6%) according to the gender variable and 380 single people(98.2%) and 7 married people(1.8%) according to their marital status. Between the leisure management sub-dimensions and the gender variable,it was observed that there was no significant difference in the goal setting and programming sub-dimensions of male and female students.However, It was found that there was a significant difference in their leisure time attitude and evaluation sub-dimensions. It is seen that there is no significant difference between the sub-dimensions of the scale and age groups in goal setting and method programming and sub-dimensions, while there is a significant difference in the sub-dimension of leisure time attitude. It is seen that there is no significant difference between the sub-dimensions of the scale and age groups in programming and evaluation sub-dimensions, and there is a significant difference in the sub-dimensions of goal setting and method and leisure time attitude. It was understood that there was no significant difference in programming sub-dimension between academic unit groups It is seen that there is a significant difference in other sub-dimensions, which are the sub-dimensions of goal setting and method, leisure time attitude and evaluation. Between the sub-dimensions of the scale and the days when students participated in leisure time activities, It was observed that there was no significant difference in the sub-dimensions of their leisure time attitude and programming. It is seen that there is significant difference in the sub-dimensions of goal setting and evaluation with method. Keywords: Kilis, Rcreation, Leisure