bluuebunny/crossref_metadata_2025 huggingface dataset:
Cobalt-Catalyzed Difunctionalization of Styrenes Enabled by Ligand Relay Catalysis
Authors: Wang Bingcheng , Sun Yufeng , Lu Zhan
Published: August 2023

Here, we report a cobalt-catalyzed sequential dehydrogenative Heck
silylation/hydroamination of styrenes with hydrosilane and diazo
compound to access 1-amino-2-silyl compounds with excellent
regioselectivity. This difunctionalization reaction could undergo
smoothly using 1 mol% catalyst loading with good functional group
tolerance. Not only di- and tri-substituted hydrosilanes, but also
alkoxysilane are suitable, which does explore the scope of the family of
1-amino-2-silyl compounds. The ligand relay phenomenon between neutral
tridentate NNN ligand and anionic NNN ligand is observed for the first
time via absorption spectra analysis in this one-pot, two-step
transformations. The primary mechanism has been proposed based on the
control experiments.
The effect of edifice slope, detachment fault geometry, and magmatic triggers on the development of volcanic flank instability
Authors: Gonzalez-Santana Judit , Wauthier Christelle , Tung Sui , Masterlark Timothy
Published: August 2023

Magmatism is a known driver of flank instability at volcanoes where
flank slip has been observed. Studies of instability at Kīlauea, Piton
de la Fournaise, and Etna imply that long-term flank motion likely
requires the presence of a layer accommodating the sliding, and a force,
such as magma intrusion, that promotes slip. We present a parametric
study using 2D Finite Element Models (FEMs), to assess how edifice
aspect ratio, detachment fault geometry, asymmetric buttressing, and
intrusion depth affect the potential for development of magma-driven
flank instability at volcanoes. We quantify whether the tested
conditions would favor flank slip based on the Coulomb Stress Changes
(CSCs) associated with endmember scenarios and showcase the expected
surface displacements for each scenario, to highlight their deviations
from half-space models. Development of instability is more likely when
flank slip is along a shallower-dipping receiver fault and the dike
intrusion spans the edifice, regardless of edifice steepness. Another
favorable scenario occurs in steep edifices with a steeply-dipping
receiver fault when the dike is beneath the edifice. Buttressing
slightly enlarges the region with conducive CSCs on shallow-dipping
faults when the dike is within the edifice but shrinks the region with
conducive CSCs in the steep edifice case with steeply-dipping faults. We
also find that neglecting topography yields different magnitudes and
extents of surface deformation, especially for steeper volcanic
edifices. This topographical effect is more important when modeling
horizontal displacements and stress fields induced by shallower
intrusions.
Environmental Contamination of Pesticides and its Toxic Effects as Endocrine Disruptors
Authors: O Yasmín Morales
Published: August 2023

The intensive use of pesticides in agriculture inevitably leads to the fact that the residues of these agrochemicals can be detected in water, air and soil. In general, these residues degrade slowly, which is why they are widely distributed in the environment, and even present at low levels, they can cause damage to human health as well as wildlife, due to their toxic, carcinogenic, mutagenic nature and teratogenic
QSAR Studies on Some C-21 Mercapto Derivatives as AntiPulmonary Inflammatory Agents
Authors: Shaik Bashirulla
Published: August 2023

Glucocorticoids have been widely used for the treatment of inflammatory conditions but are associated with various side effects. C-21 mercapto derivatives, a class of dissociated steroids, have shown potential as anti-inflammatory agents with reduced side effects. In this study, QSAR (Quantitative Structure-Activity Relationship) analysis was performed on a series of 19 C-21 mercapto hydrocortisone derivatives with IL-6 cytokine inhibition activities. Molecular descriptors were calculated using Alva descriptor software, and significant descriptors governing the activity were identified. Multiple linear regression analysis revealed statistically significant models, and the best two-variable model included spectral mean absolute deviation from reciprocal squared geometrical matrix (SpMAD_RG) and H autocorrelation of lag 3 weighted by i state (H3s). Internal and external validation confirmed the reliability of the models. The study suggests that these structural descriptors, particularly SpMAD_RG and H3s, play a crucial role in the activity prediction of C-21 mercapto derivatives. The findings contribute to the design of novel molecules in this class with improved therapeutic potential.
Touch DNA: Revolutionizing Evidentiary DNA Forensics
Authors: Bhandari Deepika
Published: August 2023

Touch DNA is an advanced technique widely employed in modern criminal justice systems in many developed countries. It aims to extract genetic information from biological substances, specifically the cells shed from the outermost layer of skin, that are left behind on touched objects. This method involves recovering trace amounts of DNA from the biological cells released during contact, even though the quantity is usually very low. The recovered DNA is further analyzed to generate a person's DNA profile. Since dead cells are not really visible to the naked eye, successfully locating and recovering them can be challenging. Performing DNA profiling from the samples that are just touched is quite difficult, hence, requires a highly sensitive approach to its proper recovery, extraction, and amplification of the segment. The methods which are used for the collection, sampling procedure, preservation, removal of contaminants, quantification of DNA, the amplifying of the genetic material, and the subsequent analysis and interpretation of the findings all play a role in how well touch DNA analysis works. Various techniques have been created over time to gather touch DNA. Reliable DNA profiles are produced thanks to the use of sophisticated kits, tools, and well-equipped forensic laboratories, which benefit the criminal justice system.
Pharmacognostic Evaluation of Platycerium bifurcatum (Cav.) C. Chr. (Polypodiaceae)
Authors: M Suleiman
Published: August 2023

Ethnopharmacological relevance: Platycerium bifurcatum (CAV.) C. Chr., Commonly known as staghorn fern is an epiphytic plant with diverse medicinal uses, such as anti-ulcer remedy, treating oedema, coughs and hypertension. This research was aim at evaluating the pharmacognostic profile of P. Bifurcatum. Methods: The fresh and air-dried plant materials were evaluated for microscopic characters, ash values, extractive values, moisture content and phytoconstituents. Results: Pharmacognostic evaluation revealed two shape of leaves, one round and the other forked-like shape, dark and light green colour, slightly coarse texture at the abaxial surface and hairy due to the trichome at the adaxial surface, reticulate leaf venation and margin entire, presence non- grandular stellate trichomes at the lower epidermal layer, spongy mesopghyll, collenchyma cells, vascular bundles straight type of epidermal cell wall, anisocytes stomata. Moisture content of 6.283%, total ash value of 8.25% within the standard range, acid insoluble ash of 1%, water soluble of 6.0% and phytochemical screening analysis shows the presence of phenolic, saponins, glycosides and triterpenoid constituents. Conclusion: this study reports the first time the pharmacognostic properties of P. bifurcatum.
Phytopharmacological Perspectives of Tinospora cordifolia Chemical Constituents and Medicinal Properties
Authors: SS Kagne
Published: August 2023

According to the World Health Organization, 80% of the world’s population relies mostly on traditional remedies including the use of plant extracts or active components. India’s mega-biodiversity and knowledge of rich historic traditional systems of medicine (Ayurveda, Siddha, Unani, Amchi, and local health traditions) give a solid foundation for the use of a wide range of plants in general healthcare and the treatment of common disorders. Tinospora Cordifolia is a Deciduous woody climbing shrub found in India, China, and Africa. It is a member of the Menispermaceae family. This plant’s pharmacological importance stems mostly from its root, stem, and leaf. It contains a variety of photoactive chemicals, including alkaloids, steroids, glycosides, lactones, polysaccharides, and others. Practically every portion of the plant has immunomodulatory effects. It is a significant medicinal plant used in Ayurveda medicine to treat colds, fevers, diabetes, and even rheumatoid arthritis.
Overview of the Complexities in Diagnosing Treating and Preventing Tuberculosis along with the Most Effective Dosage Plans
Authors: SJ Awan
Published: August 2023

Mycobacterium tuberculosis is the name of the bacterium that causes tuberculosis (TB), which typically affects the lungs. Lifetime exposure to TB bacteria increases the risk of developing TB by 5–10%. A person’s likelihood of getting sick rises if they lead an unhealthy lifestyle or have a compromised immune system. A person may take several months before showing symptoms of active TB disease. As a result, getting medical help may take longer, and the virus may spread to more people. Rifampicin, isoniazid, pyrazinamide, and ethambutol are given as part of the traditional treatment for pulmonary TB during the first two months, and then rifampicin and isoniazid are given for the following four months. For the treatment of multidrugresistant TB, levofloxacin, moxifloxacin, and bedaquiline are suggested.
History of the Taxonomic Studies of Marine Isopoda (Crustacea: Peracarida) from Argentina
Authors: Emanuel Pereira
Published: August 2023

The order Isopoda is one of the most speciose and morphologically diverse order within the Crustacea worldwide, and the Southwest Atlantic is not the exception. The knowledge of the marine isopod fauna in the Argentine Continental Shelf and Slope spans almost two centuries. It began during the 19th century and the first half of the 20th century, when European and North American scientists directed their research to this part of world. Subsequently, some Argentine researchers continued the taxonomic studies on the Isopoda, focused mainly on intertidal and shallow waters species of the continental shelf. Currently, the taxonomic knowledge of Isopoda has significantly expanded due to the access to deep-sea environments. In the present contribution, the history of the taxonomic studies of Isopoda from Argentina is reviewed.
Histopathological Investigation of Prawn Penaeus monodon in the Improved Extensive Culture Ponds of Nellore Region, Andhra Pradesh, India
Authors: S Mohan
Published: August 2023

Present work was aimed to see the quality of the prawn Penaeus monodon under improved extensive aquaculture system collected from Muthukur area of Andhra Pradesh located Pradesh located at 14.29 19 latitude and 80.10383 longitude. To assess the quality of the prawn, prawns were surveyed in the improved extensive pond and collected for histopathological investigation by adopting double staining methods (hematoxylin and eosin). Results showed that WSSV (White Spot Syndrome Virus) was characterised by prominent eosinophilic to pale basophilic intra nuclear inclusion bodies in hypertrophied nuclei of most commonly in the epithelial cells and connective tissue cells of the above target tissues. Monodon baculovirus (MBV) was characterised by intensive stained or multiple spherical or rounded hypertrophied intra nuclear inclusion bodies ranging from 0.1 m to 18 m in the epithelial cells of hepatopancreas. This kind of necrotic behaviour was also found along with acidophilic intra nuclear inclusion in hypertrophic nuclei with marginated chromatin. MBV infected shrimps showed generalised signs of disease such as lethargy, anorexia, poor feeding, dark colouration and reduced growth rate. Intensive stained basophilic hypertrophic rounded intranuclear inclusions symptoms were also found due to those disease both in eye and gill tissues. It is predicted that the prawn collected from the pond showed the symptoms of both viral and bacterial infection.
Cataglyphis convexus sp.n., A New Ant Species (Hymenoptera: Formicidae) in Tunisia
Authors: Oueslati Wala
Published: August 2023

A new Tunisian ant species, Cataglyphis convexus sp.n., is described based on the morphological traits of its workers. The species is endemic to Tunisia. The taxonomic position of C. convexus is not clear; it shares features of the altisquamis-, emmaeand bicolor-groups, but differs from all species of these genera by the presence of a V-shaped cavity at the level of the apical margin of the petiole.
Correlation of Heart Rate Response during Exercise and Recovery with Severity of Myocardial Ischemia as Judged by Electrocardiographic Findings during Treadmill Testing: Increase in Heart Rate during Recovery Suggest Severe Ischemia with Exercise Induced Left Ventricular Dysfunction
Authors: SR Mittal
Published: August 2023

We evaluated eighty one patients complaining of angina or angina equivalent symptoms on effort. Treadmill tests were performed using Bruce protocol. All confounding factors were excluded. Severity of exercise induced myocardial ischemia was decided by clinical and electrocardiographic findings during exercise and recovery. Heart rate response during exercise and recovery was correlated with severity of myocardial ischemia. Chronotropic incompetence had low sensitivity but high specificity in diagnosing severe myocardial ischemia. Decreased magnitude of reduction in heart rate during the first minute of recovery also correlated with severe exercise induced myocardial ischemia. Combining the two parameters increased sensitivity with mild reduction in specificity. Increase, rather than decrease, in heart rate during recovery period strongly correlated with severe myocardial ischemia with possibility of exercise induced left ventricular dysfunction
Effect of A Clinician-Delivered Chewing Program on Masticatory Function in Children with Cerebral Palsy
Authors: Vijayan Kavya
Published: August 2023

Objectives: Studies documenting the training effect of the Functional Chewing Training (FCT) program using objective methods are limited. The present study attempts to evaluate the effect of FCT on chewing dynamics by comparing the pre-, post-treatment and follow-up scores in children with cerebral palsy (CP). Study design: A time series design was employed to study the treatment effects. Methods: Six children with a confirmed diagnosis of oral dysphagia secondary to CP in the age range of 3 to 8 years formed the participant group. Chewing performance was assessed using Mastication Observation Evaluation (MOE, Remijn et al., 2014) and quantified using surface electromyography (sEMG) for the masseter muscle. Subsequently, 20 sessions of intensive chewing training was carried out. The assessments were repeated after intervention and at 4 weeks post-discharge, during which no intervention or home training was provided. Results: Friedman’s Two-Way Analysis of Variance revealed that there was a significant improvement in jaw, lip, and tongue scores for chewing as well as for the sEMG parameters. Wilcoxon Signed Rank test revealed that there was a significant difference in the pre- versus post-therapy and pre- versus follow-up conditions for all the parameters (p<0.017). Conclusions: The study revealed that FCT leads to improvements in lip seal, jaw stability and tongue lateralization aiding in effective masticatory performance. The continued improvement post-discharge indicates the effect of better management and progression of food textures. The present study is one of the first to elucidate the efficacy of the FCT program by illustrating the changes with respect to instrumental measures.
Interprofessional Student Education with an Otolaryngological Emphasis
Authors: LK Culley
Published: August 2023

Driven by concern about the lack of medical screening and treatment options available to uninsured members of the UNLV community, students and faculty from the UNLV Health Schools began in 2020 to investigate options for a UNLV Community Clinic that would provide free primary care to those who are uninsured. Timely screening, health education and understanding and ownership of disease is a relatively inexpensive path to prevention, early detection, and early treatment of disease. Focusing on these efforts would save patients, clinicians, and hospitals money by reducing morbidity and mortality. More importantly, the quality of America’s patient care outcomes – which are recorded as the lowest among developed countries despite having the most money spent on healthcare, would improve
A Huge Solitary Peripheral Osteoma of Mandible: A Case Report
Authors: Shrestha Sonika Dhari
Published: August 2023

Osteoma is a benign, slow-growing tumor composed of mature compact or cancellous bone. They originate from the craniomaxillo facial region such as temporal bones, sinuses, maxilla or mandible. Patients with osteomas should be evaluated for Gardner’s syndrome (GS). The treatment for osteoma is surgical excision if the lesion is symptomatic. We present a case of a solitary peripheral osteoma (PO) arising from the superior aspect of ramus of mandible causing facial asymmetry in a 22-yearold man.
The COVID-19 Impact on Inpatient Hospital Admissions in Indiaa Cross-Sectional Study
Authors: Kumar Piyush
Published: August 2023

Health is a subject of state as per the constitution of India. Hence different states of India have autonomy in deciding and reserving different percentages of beds for the COVID-19 cases as per their needs as well as availability of beds. As an example, Delhi had reserved 50% of ICU (intensive care unit) beds for COVID-19 patients. Due to the novel corona virus disease 2019 (COVID-19), we found that there have been widespread changes in healthcare access by different types of patients suffering from different diseases. Besides fear of COVID-19 Nosocomial infection, this new arrangement and prioritization of the sudden needs of huge number of COVID-19 patients it is anticipated that this situation may have reduced the IPD patients suffering from other diseases. The key researcher has observed significant change in period prevalence of IPD patients during his duties at health centres in the COVID-19 era which tempted him to find out answer to title research question. This study was done to assess that, does the COVID-19 era has affected IPD services utilization by patient (positively or negatively) of other disease on a large countrywide basis? This study will definitely help policy and decision makers to visualize the health services delivery to IPD patients of diseases other than COVID-19. This research study is an attempt to highlight the COVID-19 impacts on IPD patients of other diseases. We have started this novel study with key aim to assess positive or any negative impact of COVID-19 situation on IPD (other than COVID-19) hospital admissions count in India to assess IPD services utilization by them. We included all (public/ private/rural/urban) health facilities across 36 states and union territories of India. The data were obtained from online HMIS (Health Management Information System) of Ministry of Health and Family Welfare, GoI (Government of India). This study was not a sample survey and we included all IPDs (indoor patients) of 36 states and union territories of India. The GoI enforced an obligatory nationwide lockdown from 25th March 2020, ending on 31st May 2020. This study revealed that the mean IPD admission reduced during COVID-19 pandemic period of this study by 2048459 numbers or in percentage it was reduced by 27.55%. This study found that there is a significant reduction in various IPD admissions for medical conditions other than COVID-19, during the COVID-19 period which must be a matter of concern to important stakeholders of the health system, in the light of our knowledge that it is not possible to reduce the burden of disease in India in a small period or overnight. Governments of India should make strategies on priority to trim down burden of morbidity and mortality due to CDs as well as NCDs, in order to reap the benefits of Demographic Dividend. The COVID-19 or any such pandemic and distress management should not be prioritized at the cost of other NCDs and CDs management.
A Study among the Vendors Near Selected Educational Institutes in Chandigarh, India on Awareness of Cigarette and Other Tobacco Product Act, 2003 (COTPA)
Authors: Kumar Manoj
Published: August 2023

Introduction: Cigarettes are the only legal consumer products in the world that cause one-half of their long-term users to die prematurely. As this epidemic continues to take its toll in the United States, it is also increasing in low- and middle-income countries that are least able to afford the resulting health and economic consequences. Aim: To see the awareness of Cigarette and Other Tobacco Products Act (COTPA), 2003 in selected Educational Institution in Chandigarh. Methodology: Chandigarh was the area chosen to study the to see the awareness of Cigarettes and other Tobacco Products Act (COTPA), 2003 in Chandigarh. A Cross-sectional study was conducted from January 2018 to May 2018 to study the awareness of Cigarettes and other Tobacco Products Act (COTPA), 2003 in Chandigarh. A Self-structured questionnaire was used for collecting information on Cigarettes and other Tobacco Products Act, (COTPA) 2003. Results: Our study revealed that selling of Tobacco products to Minor then 56% respondents out of total accepted that there is selling of Tobacco products to Minor but 44% did not accept so. 40% respondents out of total accepted that there is selling of Tobacco products by Minor but 60% did not accept so. 53% respondents hold the opinion that the current level of enforcement of pictorial health warning on Tobacco products can motivate people to quit tobacco use. 47% respondents opined that the current level of enforcement of pictorial health warning on Tobacco products cannot motivate people to quit tobacco use and according to the result majority of respondents believed that current level of enforcement of pictorial health warning on Tobacco products can motivate people to quit tobacco use Conclusion: It can be concluded that majority of respondents (70%) are aware about the Cigarettes and other Tobacco products Act, 2003 as they know that there is law regarding prohibition of use of Cigarette and Tobacco product but 30% respondents were not aware about the COTPA Act, (2003).
Randomized Controlled Trial of Acceptance and Commitment Therapy for Posttraumatic Stress Disorder Symptoms in Afghan Adolescent Girls
Authors: Ahmadi Sayed Jafar
Published: August 2023

This study is a randomized controlled trial to investigate the effectiveness of acceptance and commitment therapy (ACT) on posttraumatic stress (PTSD) symptoms in adolescent girls in the aftermath of suicide attacks in Afghanistan. The participants (n = 43) were students at a private school in Kabul. The Children’s Revised Impact of Event Scale (CRIES-13) was completed by all participants after meeting the inclusion criteria. Participants were randomly assigned to experimental and control (waiting list) groups. There were 20 participants in the experimental group and 23 participants in the waiting list group. The experimental group received three ACT sessions a week for eight total intervention sessions. Four weeks after baseline, the ACT and control groups completed the CRIES-13 again. Multivariate analysis of covariance showed a significant difference between the ACT group and the waitlist control group in CRIES-13 total scores and subscales of arousal, intrusion, and avoidance at the post-test phase. We conclude that ACT resulted in an effective reduction in PTSD symptoms for adolescent Afghan girls. This success suggests that the intervention could be used in other treatment centers to reduce the symptoms of PTSD.
Adolescence Crisis, Covid-19 and Reorganization of the Family System
Authors: Aline Maguiabou Tchidjo
Published: August 2023

This article has as interest the crisis of adolescence in a context of confinement. The Adolescent Crisis is a temporary and normally transitory situation, characterized by a set of risky behaviors, which reflect not the existence of a mental disorder, but rather a difficulty in adapting to the puberty. School runaways, consumption of toxic products, risk-taking and accidents (especially traffic accidents), violence and transgressive behaviors, eating disorders, opposition to parental authority, are part of this picture. This “developmental” crisis betrays the adolescent’s desire to assert themselves and to define a personal identity, helped by their cognitive potentialities. To flourish in this direction, the adolescent needs space for expression, privacy, a spatiotemporal universe of his own. However, the coronavirus pandemic, with the confinement it imposes, forces adolescents to rub shoulders with parental authority all day long, which they normally underestimate. Isn’t this relational promiscuity likely to exacerbate the adolescent crisis? The objective of this study is to identify the specificity of the parent-adolescent relationship in times of confinement. To achieve this, we subjected four adolescents from the city of Maroua, as well as their parents, to semi-structured interviews. The speeches thus collected, after analysis, revealed relational difficulties, which affect the balance of the family system. But the situation is far from alarming. Indeed, parents tend to seize the opportunity that confinement offers them to get closer to their child, and share new experiences with them. Confinement then becomes a symbolic space conducive to the psycho-emotional development of the adolescent, through a reorganization of co-constructed interpersonal relationships. This situation, if it is well received and well interpreted by the adolescent, constitutes a barrier measure to the possible installation of psychopathological difficulties, which will have to be managed clinically after passing the Covid-19.
The Impact of Outside Friendships on Relational Satisfaction for Dating and Married Couples
Authors: George Darren
Published: August 2023

The influence of outside friendship on Couples’ relational satisfaction (RS) was explored with a sample of 444 romantically involved participants from central Alberta. There were, therefore, 222 couples, 89 of the couples were dating or engaged; 133 of the couples were Married or cohabitating. All couples were heterosexual. The primary focus of the study was to identify the relationship between the number and quality of outside friendships and relational satisfaction of the couples. Friendships were divided into three types: unshared (individual) friends, family friends, and shared (mutual) friends. A combination of the George-Wisdom Marital Satisfaction Scale and the Kansas Marital Satisfaction Scale measured relational satisfaction. Results underlined the importance of friendship-related variables on couples’ relational satisfaction; they accounted for 37% of the variance (in relational satisfaction) for men and 47.5% for women. Additional results found that individual friendships are a serious liability to couple satisfaction, family and mutual friends are associated with greater couple satisfaction. Finally, in regression analyses the families supporting the relationship and liking the partner were the greatest predictors of relational satisfaction.
Fundamental Thermal Concepts: An Assessment of University College Students’ Conceptual Understanding of Everyday Perspectives
Authors: Villarino Gil Nicetas Bareng
Published: August 2023

The phenomenon of the basic thermal concept is a challenging topic in the early learning of thermodynamics. This research investigated students' understanding of basic thermal concepts from an everyday perspective. Nineteen open-ended multiple-choice questions equipped with written justifications for the student's answer choices were used in this study. Items based on everyday perspectives avoiding scientific terminology were given to 244 university students of Leyte Normal University Tacloban City, Leyte, Philippines. This study shows that students' written responses are specific alternative conceptions commonly used. Most of the students could not provide correct reasons for their answers. The results of this study imply that the teaching style in junior and secondary schools in the Philippines may be problematic. These results can be used as a guide for developing appropriate teaching strategies in introductory physics courses, especially on heat.
Ethnomathematics Exploration of The Great Mosque of Al-Barkah, Bekasi City, Through The Learning of Geometry and Transformational Geometry
Authors: Soebagyo Joko , Luthfiyyah Fadhilah Izzul
Published: August 2023

Ethnomathematics is an understanding that makes culture a concrete form in constructing mathematical concepts. Ethnomathematics learning can help students improve their understanding of mathematical concepts and preserve Indonesian culture through an introduction to that culture. This research aims to investigate the symbolic meaning and ethnomathematics elements found in the Great Mosque of Al-Barkah. This research is qualitative research with a realist ethnographic approach. Data collection techniques were interviews, observation, documentation, and literature study. The study results prove that the Great Mosque of Al-Barkah has geometric elements (rhombuses and cuboids) and geometric transformations (reflections, rotations, and translations). Also, there are symbolic meanings in parts of the mosque. Thus, ethnomathematical elements were found in the mosque. The results of this discovery can be used as learning media and sample questions for learning mathematics at all levels of education (elementary, junior high school, and senior high school).
Ethnomathematics Exploration of Fish Trader Activities in The Traditional Market of Punggulan Village, Asahan Regency
Authors: Angraini Rini , Rakhmawati Fibri
Published: August 2023

This study aims to explore the activities of fish traders in traditional markets by connecting mathematics and culture, known as ethnomathematics. The type of research used is qualitative research with an ethnographic approach. Data collection techniques used are library data, observation, and interviews. The data analysis technique refers to the Miles and Huberman model: data reduction, data presentation, and conclusion. This study found that the activities of fish traders in traditional markets were grouped into three processes: measurement, packaging, and buying and selling. The concepts found in these three activities are measurement, sets, one-variable linear equations, weight comparisons, social arithmetic, relations and functions, two-variable linear equations, flat-sided spaces, and probability. Thus, the activities of fish traders contain ethnomathematics elements which are simultaneously an application of mathematical theory learned at school. Further researchers are advised to examine the quality of ethnomathematics-based mathematics learning.
Climate change impacts on tuber crops: vulnerabilities and adaptation strategies
Authors: Saravanan Raju , Gutam Sridhar
Published: August 2023

Climate change poses significant challenges to root and tuber crops, requiring robust adaptation strategies to mitigate vulnerabilities. This review examines the impacts of climate change on root and tuber crops, including rising temperatures, altered rainfall patterns, extreme weather events, and changes in pest and disease dynamics. These changes significantly affect root and tuber crop production, leading to lower yields, compromised quality, increased susceptibility to pests and diseases, and limited access to water resources. Adaptation strategies encompass various approaches, such as agronomic practices, crop diversification, improved water management, breeding for climate resilience, and agroecological methods. However, addressing knowledge gaps and research needs is crucial for better-understanding climate change impacts and developing effective adaptation strategies for root and tuber crops. Future research should prioritize resilient cultivar identification, enhanced cropping systems, improved pest and disease management, and exploring socio-economic dimensions of adaptation. This review emphasizes the urgent need to address climate change impacts on tropical root and tuber crops. It highlights the critical role of adaptive measures in ensuring long-term sustainability and food security in a changing climate
The challenges to the mega infrastructure of China-Pakistan Economic Corridor in Pakistan
Authors: Feng Zheng , Ali Majid
Published: August 2023

This article provides an argument for amending the China-Pakistan Economic Corridor (CPEC) in the 1973 Constitution of Pakistan. That will ensure accountability, reduce criticism of corruption, and secure Chinese investment in Pakistan. The study’s main question is why CPEC does not have constitutional protection in Pakistan, which is more investment than Pakistan’s annual budget. CPEC should reduce the sense of deprivation and inequality within Pakistan and ensure its transparency in various aspects. The CPEC Amendment can establish parliamentary oversight and reduce the deprivations of the provinces by electing members on a National Economic Council (NEC) formula and a regional basis. Furthermore, it can provide some basic constitutional framework for upcoming governments regarding heavy investment in infrastructure. The constitutional provisions of the flagship project can serve as an example for BRI member countries.
Uncredited intravascular large B cell lymphoma involving central nervous system: a great masquerader
Authors: Hon Shu Ann , See Jie Siang , Wee Jack Son , Tee Yu Jin , Jamian Ehram , Achok Hamdi , Lim Soo Min
Published: August 2023

Background:

Intravascular large B-cell lymphoma (IVLBCL) is infrequent and aggressive, clinically depicted by an almost exclusive growth of large cells within the lumen of blood vessels of all sizes. The clinical manifestations are diverse, encompassing many non-specific signs and symptoms such as fever of unknown origin, neurological symptoms, and skin lesions.

Case Presentation:

We report a case of a 49-year-old lady with unusual IVLBCL of the central nervous system. She presented with rapidly progressive dementia preceded by seizures and a short history of altered sensorium. There were no cutaneous lesions. Plain computed tomography brain showed no significant abnormalities. Cerebrospinal fluid analysis was normal except for mildly raised protein. Antinuclear antibody was positive 1:320 but the remaining autoimmune workups were negative. Electroencephalogram showed cortical dysfunction with occasional sharp wave at the right frontoparietal region. Other dementia workups were unremarkable. Magnetic resonance imaging brain revealed non-enhanced biparietal gyri hyperintensities which may represent encephalitis changes. She was empirically treated for viral encephalitis, however, there were still recurrent seizures despite adequate anti-seizure medications with minimal improvement of symptoms. Subsequent admissions noticed bicytopenia with elevated lactate dehydrogenase. Bone marrow aspirations and trephine biopsy disclosed High-Grade Mature B Cell Lymphoma germinal center B-cell Type. She was subsequently managed by the hematology team and started with conventional rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone therapy. Fortunately, she is currently on the road to recovery.

Conclusion:

High index of suspicion is warranted to diagnose early in order to have a better prognosis.
Historia global: debates y tendencias en América Latina y el Caribe
Authors: De la Mora Rogelio
Published: August 2023

Presentación de la sección temática.
Derechos Humanos y Desarrollo, Dimensiones e Indicadores para la Medición Multidimensional de la Pobreza
Authors: Manrique Molina Filiberto Eduardo R.
Published: August 2023

El presente artículo emplea el horizonte metodológico con base en la analítica comparada, pretende mostrar la aplicación del método de medición de la pobreza multidimensional en dos regiones del mundo. El método permite identificar las privaciones a las funciones y capacidades de las personas, identificar quiénes son los pobres, evitar su condición de pobreza, generar acciones jurídicas que permitan la equidad y acabar con las desigualdades y afectaciones a los derechos humanos que trae consigo la pobreza multidimensional. Lo cual es esencial en la agenda 2030 que busca el desarrollo humano, la garantía de los derechos y la dignidad de millones de personas.
A Planet in Distress: Cross-Curricular Integrations of Visual Texts in the Mainstream Learning Context
Authors: De Jager Nicholas , Steyn Maretha
Published: August 2023

This article aims to explore the affordances of employing the visual mode— specifically the medium of drawing—as a multimodal pedagogy to raise awareness of deforestation and climate change in the South African mainstream school context. Conducted at several public and private schools in the Gauteng and the North West provinces, the research follows nine learners between the ages of 10 and 18, who have volunteered to participate in a three-week enrichment programme involving the multimodal reimagining of a non-curricular narrative into a series of drawings, paintings and collages. The narrative, which also serves as the primary source text during each participant’s artefactual redesign journey, is a wordless picture book that explores the concept of exponential environmental change. With this visually engaging text merely acting as a springboard for the making of new meanings in the Grade 5 to 11 Social Sciences/Geography classroom, participants are granted complete autonomy in their visual representations of how the exhaustion of our natural resources and moreover the threat of global warming may be impacting upon our daily lives on a spiritual, emotional and corporeal level. Finally, each artefact is presented as primary data to offer a tripartite focus on the latter learner experiences, the expressional properties of art, as well as the viability of the proposed pedagogy in future practice.
Use of a combination of the virus-neutralizing monoclonal antibodies casirivimab and imdevimab for mild to moderate COVID-19 in patients at high risk of progression: Results of the non-interventional observational study
Authors: Lebedkina Marina S. , Fomina Daria S. , Mutovina Zinaida Y. , Mаrkina Ulyana A. , Bogomolov Pavel O. , Chulanov Vladimir P. , Lysenko Mariana A. , Alexeeva Ekaterina I.
Published: August 2023

Aim. To evaluate the efficacy and safety of a combination of virus-neutralizing monoclonal antibodies MAB (casirivimab and imdevimab) in patients with mild to moderate COVID-19 with risk factors in real word settings.
Materials and methods. A non-interventional non-comparative observational study with primary prospective data collection included 108 patients with mild to moderate COVID-19 (mean age 61 years), who had risk factors for developing severe disease. All patients (n=108) were treated with a combination of MAB casirivimab and imdevimab intravenous single infusion 1200 mg (600 mg of each component). The efficacy and safety of MAB were assessed at 7, 14, and 28 days after infusion.
Results. Efficacy. Indications for hospitalization by day 7 from the moment of MAB administration were in 0.9% (n=1), by day 14 in 1.9% (n=2), by day 28 in 0.9% of patients; to stay in the intensive care units by the 7th day in 4.6% (n=5), by the 14th day in 0.9% (n=1), by the 28th day in 0.9% (n=1) patients. During 28 days of follow up, the need for mechanical ventilation and extracorporeal membrane oxygenation was registered in 2/108 (1.8%) patients. There were no deaths directly related to COVID-19 in the assessed cohort of patients. Safety. By the 28th day of the follow up, no adverse effects due to MAB therapy were registered.
Conclusion. An analysis of the results of a non-interventional observational study summarized in this article showed the high efficacy and safety of virus-neutralizing MAB combination (casirivimab and imdevimab) in patients with mild to moderate COVID-19 with of risk factors for severe COVID-19 in real word settings.
A Call to Action for a Comprehensive Earthquake Education Policy in Nepal
Authors: Hetényi György , Subedi Shiba
Published: August 2023

Earthquakes in Nepal are among the most damaging natural hazards, claiming many lives and causing more widespread destruction than any other natural hazard. Yet, due to other difficulties and challenges, earthquakes are at the forefront of people’s attention only after major events, such as the 1934 or 2015 earthquakes. As a result, current preparedness of the population to earthquakes is far below the optimal level. This calls for an immediate and widespread educational effort to increase awareness and to raise the current young generation responsibly. After describing the current status of earthquake education at various school levels in Nepal, we here propose a series of actions to undertake towards an official education policy, starting from full openness and use of languages, via coordination and teacher's training, to the content, frequency and style of curriculum. We conclude on a timeline of actions, which have various lengths but should start today. We hope that by sharing our researcher and educational experience and thoughts, the actual preparation of the earthquake education policy for Nepal will start being developed under a dedicated team. Elements of the proposal presented here can be used and adapted to other regions at risk around the world.
False positives are common in single-station template matching
Authors: Muir Jack , Fernando Benjamin , Barrett Elizabeth
Published: August 2023

Template matching has become a cornerstone technique of observational seismology. By taking known events, and scanning them against a continuous record, new events smaller than the signal-to-noise ratio can be found, substantially improving the magnitude of completeness of earthquake catalogues. Template matching is normally used in an array setting, however as we move into the era of planetary seismology, we are likely to apply template matching for very small arrays or even single stations. Given the high impact of planetary seismology studies on our understanding of the structure and dynamics of non-Earth bodies, it is important to assess the reliability of template matching in the small-n setting. Towards this goal, we estimate a lower bound on the rate of false positives for single-station template matching by examining the behaviour of correlations of totally uncorrelated white noise. We find that, for typical processing regimes and match thresholds, false positives are likely quite common. We must therefore be exceptionally careful when considering the output of template matching in the small-n setting.
Pemberdayaan Masyarakat dalam Upaya Menurunkan Angka Kejadian Berulang Ruam Kulit Balita di Desa Mranggen Demak
Authors: Soesanto Edy , Sulistyawati Erna , Amalia Nur Ulfa , Julistyanissa Dian , Wati Astiani Nur Kharisma , Sari Rita Nur Mulya , Udayanti Dyah Retno
Published: August 2023

Masalah kulit yang banyak dialami balita yaitu miliaria atau biang  keringat yang mengakibatkan terjadinya ruam kulit. Tujuan  kegiatan ini adalah untuk menurunkan angka kejadian  berulang ruam kulit balita melalui pendidikan kesehatan  perilaku hidup bersih dan sehat ke ibu yang memiliki balita  di posyandu balita Jatikusuma 2 dan 3 Desa Mranggen  Demak. Kegiatan ini melibatkan pemerintah desa, tokoh  masyarakat, kader kesehatan dan para ibu dengan balita di  wilayah kerja posyandu balita Jatikusuma 2 dan 3 Desa  Mranggen, Demak. Kegiatan ini dilakukan tiga tahap yaitu perencanaan, pelaksanaan, evaluasi, dan tindak  lanjut. Perencanaan dilakukan untuk mengedukasi ibu dengan anak usia 0-5 tahun tentang pentingnya PHBS guna mencegah terjadinya kejadian berulang ruam kulit.  Pelaksanaan pendidikan kesehatan dilakukan dengan  metode small group discussion yaitu dengan membagi tiap  ibu setelah pemeriksaan posyandu menjadi kelompok kecil  terdiri dari 3 penyaji data dan 5 ibu yang memiliki balita. Kegiatan dilaksanakan dengan baik dan mendapat respon kooperatif, antusias, dan aktif setiap kegiatan dilakukan.
Peningkatan Kesehatan Reproduksi Remaja Melalui Pembentukan Pos Bimbingan Dan Pelayanan Kelompok Kader Sebaya
Authors: Rejeki Sri , Warsono Warsono , Khayati Nikmatul , Hidayati Eni
Published: August 2023

Berdasarkan data hasil survei pada remaja Kabupaten Kendal tahun 2019 diperoleh 52 % remaja merokok, menonton gambar porno 95 %, 16 % remaja miras dan narkoba serta 7 % pergaulan bebas/ sex pra nikah dan lain-lain. Banyaknya remaja menganggur dan sering bergerombol dengan teman sebaya. Hal ini sangat memprihatinkan. Sudah banyak pihak yang berupaya untuk menangani permasalahan remaja, namun penangananya tidak secara komprehensif bersifat fragmented dan parsial. Sehingga penanganan tersebut tidak optimal.Permasalahan remaja yang disebutkan di atas berkaitan erat dengan kesehatan reproduksi, dan seringkali berakar dari kurangnya informasi dan pemahaman serta kesadaran untuk mencapai sehat secara reproduksi. Akses untuk mendapatkan informasi bagi remaja banyak yang tertutup. Dengan memperluas akses informasi tentang kesehatan reproduksi remaja yang benar dan jujur bagi remaja akan membuat remaja makin sadar terhadap tanggung jawab perilaku reproduksinya. Meski Puskesmas sebagai tempat Klinik Reproduksi Remaja (Klinik Peduli Remaja) sudah dicanangkan pemerintah, namun akses remaja terhadap tempat layanan tersebut sangatlah rendah. Beberapa data mengungkapkan bahwa setting ruangan, pola pelayanan, pola pakaian yang serba putih, terbatasnya jam buka, dan nilai-nilai normatif tenaga provider yang tidak gaul menjadi penyebab utama enggannya remaja datang ke tempat pelayanan tersebut.Dengan demikian remaja sangat membutuhkan adanya edukasi dan pendampingan remaja yang berfungsi memberikan informasi kesehatan khususnya kesehatan reproduksi dan segala permaslahanya,  deteksi sederhana masalah kesehatan. Selain itu juga dibutuhan tenaga (kader) yang siap meberikan konsultasi yang mudah di jangkau dan selalu siap yang dapat diambil dari kalangan remaja itu sendiri (Kader Sebaya) yang dapat berperan sebagai konselor sebaya dalam dalam penyelesaian masalah-masalah yang berdampak pada kesehatan reproduksi.