bluuebunny/crossref_metadata_2025 huggingface dataset:
Efeitos colaterais do uso contínuo de Isotretinoína, uma visão abrangente
Authors: Camargo Brendha , Lima Lana Paola Almeida Santos , Gatti Amanda Botte , De Oliveira Maiara Radunz , De Oliveira Raíssa Radunz , Da Silva Sabrina Rodrigues , Montedor Thalita Sargi , Mendonça Gabriela Vieira Gouvêa , Greco Pamela Amicucci , Zanoni Rodrigo Daniel
Published: December 2023

A isotretinoína é um medicamento eficaz no tratamento da acne grave, mas deve ser usada com cautela sob orientação médica devido aos seus potenciais efeitos colaterais e riscos, No entanto, a isotretinoína é uma medicação potente com potenciais efeitos colaterais significativos. Portanto, seu uso requer acompanhamento médico rigoroso, e é comum que os pacientes sob tratamento com isotretinoína sejam submetidos a exames de sangue regulares para monitorar sua saúde. Realizou-se uma revisão literária nas bases de dados PubMed, Scopus e BVS, abrangendo publicações de 2010 a 2023, com as palavras-chave "Isotretinoína," "Roacutan," "Efeitos Isotretinoína," e "Acne Vulgar." Foram incluídos estudos originais, revisões, protocolos de uso e relatos de casos que abordaram os efeitos colaterais da isotretinoína, com foco em teratologia, sintomas depressivos, alterações hepáticas e lipídicas, aumento dos níveis de CPK e outros efeitos colaterais comuns. Essa análise fundamentou as considerações finais sobre o uso contínuo da isotretinoína no tratamento da acne vulgar. Os estudos analisados revelaram uma ampla gama de efeitos adversos associados ao uso contínuo de isotretinoína. Entre esses efeitos, destacam-se a teratologia, com riscos de malformações congênitas em fetos de mulheres grávidas expostas à substância. Além disso, observou-se uma correlação entre a isotretinoína e sintomas depressivos em alguns pacientes. Efeitos colaterais adicionais incluem alterações hepáticas e lipídicas, aumento dos níveis de CPK, problemas gastrointestinais, halitose e problemas dermatológicos, como ressecamento da pele e lábios rachados. O uso contínuo de isotretinoína no tratamento da acne vulgar é eficaz, mas requer uma avaliação cuidadosa dos riscos e benefícios. Para minimizar os efeitos colaterais adversos, a terapia deve ser monitorada por profissionais de saúde qualificados e estritamente regulamentada para prevenir a exposição fetal. A conscientização do público sobre os perigos do uso indiscriminado da isotretinoína é essencial, enfatizando a importância de procurar orientação médica antes de iniciar o tratamento. A decisão de utilizar a isotretinoína deve ser informada e equilibrada para garantir que os pacientes alcancem os benefícios desejados sem comprometer sua saúde geral.
Mechanism of Regulation on the Marketing of the Breast–Milk Substitutes: a Lesson Learn from one Province in Northern of Thailand
Authors: Maneemai Ongart , Kittiwongsunthorn Worawit , Choorassamee Jantima , Ob-un Kunwara , Suwannapoj Kantapong , Rattanatanyapat Pitchayut
Published: December 2023

Objectives: To investigate the existing model and mechanism for surveillance of the marketing of food for infants and young children in Phayao province, Thailand according to The Control of Marketing of Infants and Young Children Food Act, B.E. 2560 (2017).
 
Method: This research was a qualitative research study which collected data through an in-depth interview and a focus group with 7 informants: officers of Phayao Provincial Public Health Office, registered nurses, public health technical officers, and consumer network officers.
 
Results: Phayao province had a control model and mechanism on the marketing of food for infants and young children according to The Control of Marketing of Infants and Young Children Food Act, B.E. 2560 (2017) as follows: (1) For passive surveillance, there was a complaint center at the Provincial Public Health Office as the main coordinator to receive complaints and prepare files of violation cases. (2) Active surveillance included visits to target places such as shops and child development centers, and visits to enforce maternal and child health standards. Finally, (3) networking and knowledge dissemination were implemented through the first 1,000 miracle days of life project. The implementational model for controlling the marketing of food for infants and young children should be as follows: (1) Be compliant with laws. (2) Determine clear policies at the departmental levels. (3) Work collaboratively at the provincial, district, and subdistrict levels. (4) Increase participation of related people for surveillance of offences. (5) Empower operational networks, entrepreneurs, and other people to gain knowledge and be compliant with the law in a suitable way. (6) Use communication technology to support implementation.
 
Conclusion: Phayao province has a model and mechanism to control the marketing of food for infants and young children in compliance with the law. The model and mechanism should be developed according to the area contexts to support the implementation to be more effective.
Performance of Women-Led Smes in Indonesia: The Role of Financial Inclusion, Financial Literacy, and Technology adoption
Authors: Tubastuvi Naelati , Purwidianti Wida
Published: December 2023

Purpose: Women entrepreneurs have an important role in increasing economic growth. This research aims to explore the relationship between financial literacy, technology adoption, financial inclusion and women SME performance.
 
Theoretical framework: Resource based theory is used as the theory underlying the influence of technology adoption on financial inclusion. The Technology Acceptance Model (TAM) theory explains the influence of technology adoption on company performance. Upper echelon theory is used as the basis for the relationship between financial literacy, financial inclusion and SME
 
Design/methodology/approach: The population was women-owned SMEs in Indonesia. A total of 250 female SME owners were drawn as respondents. This study used convenience sampling method. Data were collected using a structured questionnaire.
 
Findings: The results showed the contribution of financial literacy and technology adoption to financial inclusion. There is an influence of technology adoption on the performance of women's SMEs. The direct influence of financial literacy on SME performance is not supported. The mediating role of financial inclusion in the effect of financial literacy and technology adoption on the performance of women's SMEs is supported. The direct influence of financial literacy on SME performance is not supported. 
 
Research, Practical & Social implications: This study can provide a real contribution to the government in developing women-owned SMEs by paying attention to financial literacy, technology adoption and financial inclusion of women SME owners
 
Originality/value: This research provided novelty by examining the mediating role of financial inclusion in the effect of financial literacy and technology adoption on the performance of women's
Juridical Analysis of Wanprestation of One of The Parties in The PPJB Deed Regarding Land Rights
Authors: Sihombing Irene Eka
Published: December 2023

Objective: Juridical analysis of defaults committed by one of the parties in the Deed of Sale and Purchase Agreement (PPJB) regarding Land Rights. Default is a crucial issue in property transactions, affecting the validity and implementation of contracts. The focus of this research is to identify, analyze and evaluate juridical aspects related to default in the context of PPJB land rights.
 
Method: This research method involves analysis of applicable legal norms, related court decisions, and literature reviews. In this analysis, various forms of default will be discussed, their legal implications, and efforts to resolve them. Apart from that, this article also considers the role of the Sales and Purchase Agreement Management (PPJB) and related parties in preventing and dealing with default.
 
Results: It is hoped that the results of this research can provide guidance for property business people, legal practitioners and researchers to understand the dynamics of default in the context of PPJB land rights. The conclusions of this analysis will illustrate the impact of default on contract integrity and highlight legal strategies that can be taken to handle cases of default in property transactions.
Legal Policy in the Decision of the Constitutional Court and the Formation of Law
Authors: Perbawa I Ketut Sukawati Lanang Putra
Published: December 2023

Objective: The purpose of this research is to raise the Criminal Law Act as a hotly debated topic. Some people think that the Constitutional Court should have the courage to make a legal breakthrough on this very important issue. However, the Constitutional Court judges are of the opinion that expanding the meaning of adultery is not within their jurisdiction. This research aims to examine further the legal arguments of the Constitutional Court's decision which is an open legal policy and its implications for the formation of laws and regulations in Indonesia.
 
Method: The research method used is literature research with a legal approach and case studies of several Constitutional Court decisions which contain open legal policy arguments. Conceptually, this research will also discuss the implications of the Constitutional Court's decision containing the open law policy for the national legislative system.
 
Results: The research results show that first, the concept of open legal policy in Constitutional Court decisions does not yet have clear boundaries so that the meaning of positive legislator and negative legislator is often confused in the practice of forming and reviewing laws. This decision, which is an open legal policy, also shows that there has been a tug-of-war between the judges of the Constitutional Court in using the paradigm of judicial activism and judicial restraints, giving rise to legal uncertainty in society.
Formation of Women’s Advisory Groups and Their Role in Strengthening the Social Status of Women (Using The Example of Public Service Centers)
Authors: Niyazova Nargiza M.
Published: December 2023

Objectives: The first section of this discussion focuses on outlining the primary objectives that guide the exploration of the gender approach. Understanding the significance of addressing gender-related issues in contemporary society sets the stage for a comprehensive examination of economic, social, and peace-related challenges affecting both women and men.

 

Methods: In this segment, the methods employed to investigate and analyze the gender approach are elucidated. Whether through qualitative research, statistical analysis, or a combination of methodologies, this section provides insights into the strategies used to gain a deeper understanding of the impact of gender dynamics on various aspects of human life in the 21st century.

 

Results: The third subsection delves into the outcomes and findings derived from the study of gender-related issues. This could include statistical data, case studies, or empirical evidence that highlights the tangible effects of gender inequality on economic and social realms, as well as its implications for peace and security.

 

Conclusion: The final part synthesizes the key insights and draws conclusions based on the objectives, methods, and results presented earlier. It reflects on the broader implications of the gender approach, acknowledging its role as an integral component of sustainable development, as endorsed by Goal 5 of the UN’s 2030 agenda. This section emphasizes the fundamental human right of gender equality and its crucial contribution to fostering a peaceful and sustainable global existence. [1]”
The Formation of National Pride in The People of Central Asia: An Academic Perspective
Authors: Narkulov Sukhrob D. , Karimov Nodir R. , Makhmudov Laziz Y. , Alimova Rahima R. , Otaev Gayrat G. , Siddikov Ravshan , Roziev Bobosher U. , Umarova Farida S.
Published: December 2023

Objectives: The primary objective of this article is to comprehensively explore the formation of national pride in Central Asian people. The focus is on academic investigation, aiming to uncover the historical, cultural, and socio-political contexts that have played pivotal roles in shaping the development of national identity and pride within this region. The article aims to provide a nuanced understanding of the multifaceted factors influencing Central Asians' sense of pride.

 

Methods: To achieve the stated objectives, the study employs a methodological approach that involves delving into various dimensions of Central Asian history and culture. Methodologies include examining language dynamics, religious influences, the impact of colonial legacies, the significance of cultural heritage, and the role of political movements. By employing a multidimensional analysis, the article aims to capture the complex interplay of factors contributing to the formation of national pride.

 

Results: The results of this study present a nuanced and comprehensive understanding of the characteristics that have contributed to the formation of national pride in Central Asian people. The examination of historical, cultural, and socio-political factors provides valuable insights into the intricate dynamics shaping the region's sense of identity. The results highlight the multifaceted nature of Central Asian national pride, acknowledging the diverse influences that have played roles in its development.

 

Conclusion: In conclusion, the article synthesizes the findings by underlining the significance of understanding the complexities surrounding the formation of national pride in Central Asian people. The multifaceted factors explored, including language, religion, colonial legacy, cultural heritage, and political movements, collectively contribute to the intricate tapestry of Central Asian identity. The conclusion emphasizes the need for a holistic and context-aware perspective when analyzing national pride, recognizing its dynamic nature and the interplay of diverse influences within Central Asia. Overall, the article contributes to the academic discourse on identity formation and national pride in the region.
The Socio-Economic Situation in An Uzbek Village in the 20-30s of the Xx Century: from Reforms to Collectivization
Authors: Makhkamova Nodira R.
Published: December 2023

Objectives: The primary objectives of this article center on analyzing the socio-economic situation in an Uzbek village during the 20-30s of the XX century. The study aims to understand the impact of Soviet power on rural areas, specifically focusing on the presence and influence of the government during the initial years. Additionally, the objectives include examining the period of reforms in the 20s that led to significant improvements in the economic indicators of the agricultural sector.

 

Methods: The research methodology involves a historical analysis of the socio-economic conditions in the Uzbek village during the specified time frame. It includes a detailed examination of archival documents, historical records, and relevant literature to trace the changes in the rural landscape. The methods also entail a closer look at the policies implemented during the 20s, such as reforms and their effects, leading up to the initiation of collectivization and dispossession in 1929.

 

Results: The findings of the study highlight the initially unfelt presence of Soviet power in rural areas during the first years. The 20s, marked by reforms, saw significant economic improvements in the agricultural sector. However, the results underscore the detrimental impact of the subsequent policies of collectivization and dispossession in 1929. These policies transformed the role of the Uzbek farmer from an owner to a worker, leading to the destruction of the institution of private property and causing a tragic disruption in the once peaceful social life of the village.

 

Conclusion: In conclusion, the study reveals the dual nature of the Soviet influence on the Uzbek village during the 20-30s. While the initial years brought about positive economic changes through reforms, the subsequent policies had severe consequences, destroying the institution of private property and disrupting the social fabric of the village. The conclusion emphasizes the profound impact of governmental policies on local farmers and the transformation of their socio-economic status during this crucial period.
Anioł stróż jako niebiańskie ja człowieka w sofiologiiSergiusza Bułgakowa
Authors: Hrynchyk Katsiaryna
Published: December 2023

Wśród wielu prób teologicznego opisania rzeczywistości anielskiej, angelologia prawosławnego teologa Sergiusza Bułgakowa stanowi jedno z niewielu podejść całościowychi jest z tego powodu niezwykle interesująca. Nauka o aniołach rosyjskiego teologa toczęść systemu teologicznego, który zostaje określony mianem sofiologii. Celem artykułu jest ukazanie dość oryginalnej nauki o aniołach stróżach, jaką prezentuje w swoimpodejściu Bułgakow. W jego systemie można zauważyć daleko idące podobieństwodo świata idei Platona. U Bułgakowa każda rzecz ma swojego anioła, podobnie jaku Platona posiada swoją ideę. Aniołowie są opiekunami świata ziemskiego, są ściślepowiązani z nim i prowadzą go do realizacji nadanego mu sensu. A w aniele stróżuBułgakow widzi wyższe niebiańskie ja każdego człowieka, którego on otrzymujew akcie stworzenia jako swego przyjaciela, duchowego bliźniaka, z którym dusza prowadzi tajemniczy dialog.
Zastosowanie elementów psychologii pozytywnejw rzeczywistości edukacyjnej
Authors: Król Katarzyna
Published: December 2023

W 2022 r roku Rzecznik Praw Dziecka stworzył raport z Ogólnopolskiego badaniajakości życia dzieci i młodzieży w Polsce przeprowadzonego w 2021 r. Uzyskane wyniki określiły poziom funkcjonowania dzieci i młodzieży w czterech najważniejszychdla nich sferach życia: psychicznego, społecznego, rodzinnego, wirtualnego. Badaniate pokazały, że są pewne obszary, w których dobrostan polskich uczniów jest poniżejoptymalnego. W wyniku badań autorzy sformułowali szereg zaleceń i interwencji koniecznych do podjęcia, aby ten stan rzeczy poprawić. Zalecenia te mają być zaczątkiemdo zmian prawnych i ustawowych. Niniejszy artykuł jest propozycją działań skierowanych „od dołu”, a możliwych do wprowadzenia już teraz w rzeczywistości edukacyjnej,aby poprawić dobrostan uczniów w sferach życia, dotyczących zdrowia psychicznegoi edukacji. Przytoczona teoria psychologii pozytywnej w kontekście badań rzecznikapraw dziecka oraz modele pracy edukacyjnej to propozycje mogące poprawić jakośćżycia i dobrostan uczniów.
CONDUTAS FRENTE AO PACIENTE VÍTIMA DE POLITRAUMA: UMA REVISÃO DE LITERATURA
Authors: Ramos Ariel Fernandes , Aguiar Thayla Souza , Lopes Graciana de Souza
Published: December 2023

O presente estudo teve como objetivo descrever sobre as condutas frente enfermeiro frente ao politraumatismo. E especificamente, discriminar as condutas do enfermeiro no atendimento imediato ao politrauma e descrever sobre os impactos fisiológicos do politrauma. Trata-se de um estudo analítico, que utiliza como técnica a Revisão Integrativa da Literatura. A busca foi realizada dentro das bases de dados dentro da Biblioteca Virtual de Saúde (BVS): SCIELO, BDENF e LILACS, por meio da junção de três DeCS, cruzados com operador booleano “Conduct” AND “Polytrauma” AND “Urgency and Emergency”. Os resultados evidenciaram que a presença do enfermeiro é fundamental no atendimento inicial a pacientes com politraumatismos, independentemente do cenário clínico. Estes profissionais são responsáveis pela identificação precoce de sinais e sintomas, pelo planejamento de intervenções e pela implementação de procedimentos eficazes, todos com o objetivo de minimizar os efeitos fisiológicos adversos e promover uma resposta adequada ao trauma. Além disso, a identificação dos sintomas fisiológicos do politrauma em vários sistemas orgânicos reforça a necessidade de uma abordagem holística no cuidado ao paciente. Portanto, os enfermeiros desempenham um papel central na avaliação e monitoramento dos sinais de cuidado, fornecendo suporte emocional aos pacientes e seus familiares, prevenindo complicações e promovendo a recuperação e a adaptação adequada.
SEPSE NEONATAL: FATORES DE RISCO E CONDUTAS DA ENFERMAGEM
Authors: De Lima Nayara Brenda Batista , Pacheco Camila Aquino , De Sales Lorrana Barbosa , Da Silva Rennan Rodrigues Nunes , Do Vale Emilly Mariana Nihira , Silva Lorena Souza , Pereira Elcivana Leite Paiva , Lopes Graciana de Sousa
Published: December 2023

A sepse neonatal é uma condição grave que demanda atenção multiprofissional especializada. Fatores de risco, como o nascimento antes do tempo adequado e peso reduzido no momento do parto, aumentam a vulnerabilidade do recém-nascido. Portanto, as ações realizadas durante a etapa neonatal desempenham um papel fundamental na promoção da saúde e na prevenção de possíveis complicações. O objetivo deste estudo é fornecer uma descrição dos principais elementos de risco relacionados à sepse neonatal e como a assistência de enfermagem pode influenciar no processo de recuperação dos recém-nascidos. O conhecimento desses aspectos é fundamental para a promoção da saúde neonatal e a redução da morbidade e mortalidade associadas à sepse.
Medicated urea molasses mineral block and tannin on growth performance, nutrient utilization and nematodosis in goat kids
Authors: ROY ANGAN , TIWARI S P , SAHU TARINI , NAIK SURENDRA KUMAR , DONERIA RAINA
Published: December 2023

Indigenous goat kids (20; 3 to 5 months, average body wt-12 kg) were offered ad lib. rice straw and berseem hay (40:60) to assess growth performance and nutrient utilization. Group 1 was fed concentrate mixture (100g/d). Groups 2,3,4 and 5 were supplemented with urea molasses mineral block (UMMB), medicated urea molasses mineral block (Med-UMMB containing fenbendazole @0.5g/kg), tannin (5% of DM) and UMMB plus tannin (5% of DM) respectively. The animals were given trickle infection (200L3/d) of gastrointestinal nematodes (Haemonchus sp. and Cooperia sp. in the dose ratio of 9:1) for consecutive 10 days. Dry matter (DM) intake, total digestible nutrient (TDN) intake, growth performance and nitrogen (N) balance revealed no significance between treatment and control whereas digestible crude protein (DCP) intake, calcium (Ca) and phosphorus (P) balance for T2, T3 and T5 showed significant improvement over control. Humoral immune response against calf red blood cells (CRBC) was significantly higher in T4 as compared to control. Thus it may be concluded that dietary supplementation of med-UMMB and tannin have no effect on growth performance whereas tannin significantly improved the humoral immune response of kids.
Comparison of heritabilty estimates from time series and least squares adjustments in Sahiwal cattle
Authors: SENTITULA SENTITULA , GANDHI R S , KUMAR AMIT
Published: December 2023

The data on 594 first lactation records of Sahiwal cows spread over 46 years (1961–2006) were analyzed by least squares and time series analyses for ascertaining correction factors to adjust the data for non-genetic factors to estimate heritability of first lactation traits. The traits considered were, age at first calving (AFC), first lactation total milk yield (FLTMY), first lactation 305-day or less yield (FL305DMY), first lactation length (FLL), first dry period (FDP), first service period (FSP) and first calving interval (FCI). A least-squares model incorporating 15 periods (3 years each), 12 months and AFC as co variable was fitted for all the traits except for AFC (Set-1). Least squares model comprising months, exact periods (3–7 years for various traits) and AFC as co variable comprised Set-III and Set- IV incorporated data adjusted by AFC, exact periods (3–7 years) and by monthly indices derived from time series analysis. The data were adjusted for significant non-genetic factors to estimate heritability from all the four sets. Higher estimates of heritability of majority of the traits from data adjusted by monthly indices and exact periods derived from time series analysis as compared to least squares adjustments revealed that the correction factors derived from time series analysis seem to be more appropriate to adjust the animal breeding data for non-genetic factors in Sahiwal cattle.
IMPACT OF PERCEIVED USEFULNESS, PERCEIVED EASE OF USE AND CONSUMER TRUST ON BEHAVIORAL INTENTION
Authors: Reta Tata Pratiwi  , Purwanto SK  , Nina Nurhasanah
Published: December 2023

This study aims to examine and analyze the effect of Perceived Usefulness, Perceived Ease of Use and Consumer Trust both partially and simultaneously on Behavioral Intention in the Traveloka Application. The research approach used in this research is quantitative research. The population in this study are consumers who use the Traveloka application. Data was collected using the survey method by distributing questionnaires to respondents who have purchased tickets through the Traveloka application, purchased tickets using the Traveloka application in the last 6 months and are in the Jabodetabek area. Questionnaires collected as many as 150 respondents, the data is then processed using multiple linear regression methods. Results of data analysis performed with the help of SPSS tools. Based on the results of this analysis it is known that the variables Perceived Usefulness, Perceived Ease of Use and Consumer Trust simultaneously have a positive effect on Behavioral Intention in the Traveloka Application. Partially the variables Perceived Usefulness, Perceived Ease of Use and Consumer Trust have proven to have a positive effect on Behavioral intention in the Traveloka Application. It can be stated that the easier the use of the Traveloka Application, the better the benefits of the application, and the greater the consumer trust, which leads to an increased intention to use the Traveloka Application. It is expected that the findings of this research, along with support from other studies, can provide a strong foundation for guiding the future development of the Traveloka application.
PELATIHAN MANAJEMEN DATA BISNIS UNTUK MENDUKUNG PROSES DIGITALISASI PADA YAYASAN BINA MULIA INDONESIA
Authors: Khaerudin Muhammad , Andy Achmad H  , Srisulistiowati Dwi Budi , Sri Rejeki
Published: December 2023

Dalam rangka menyikapi era digitalisasi, Yayasan Bina Mulia Indonesia yang menaungi beberapa jenis usaha seperti Taman Kanak Kanak, Taman Pendidikan Al-Quran, Koperasi dan toko, agar semua jenis usaha dapat beradaptasi dengan era digital, mereka perlu membuat perubahan pada budaya organisasi, pemikiran strategis, dan keterampilan serta pengetahuan. Sebuah organisasi perlu menjadi lebih fleksibel, kreatif, dan terbuka    terhadap keadaan teknologi yang terus berkembang. Keamanan data, integrasi sistem yang kompleks, pergeseran pasar dan dinamika persaingan hanyalah beberapa risiko dan tantangan yang ditimbulkan oleh transformasi bisnis ini.

Teknologi Informasi yang sudah banyak diimplementasikan ke dalam Model Bisnis menggambarkan bagaimana pergeseran model bisnis akibat dari berkembangnya kemajuan teknologi. Operasi organisasi, interaksi pelanggan, dan generasi nilai semuanya telah berubah secara mendasar oleh pengaruh teknologi informasi di jaman modern. Dari hasil temuan didapatkan bahwa semakin pesat perkembangan zaman maka semakin sengit persaingan antar lembaga, oleh karena itu pula semakin besar tuntutan suatu lembaga terhadap pengembangan sumber daya manusia yang berkualitas. Dalam praktiknya, pada era digitalisasi ini pengembangan sumber daya manusia dapat dilakukan dengan efektif dan efisien melalui pendidikan dan pelatihan digital.
Protect Hakka Architecture: A Concept of Cultural Inheritance
Authors: Huan Wang , Mohamed Fauzi Naeim , Peixin Liu
Published: December 2023

Hakka culture takes the traditional culture of the Han nationality as its core, and the breeding and formation of Hakka culture conform to the laws of cultural development. It is a complete system that integrates Hakka customs, values, and aesthetic sentiments. However, preserving traditional Hakka buildings confronts challenges due to a lack of protection awareness and negative external impacts. It is urgent to explore strategies and approaches for the protection and sustainable development of the Hakka architecture. We conduct ethnographic research methods in fieldwork, which can provide the researchers with detailed and rich resources to further support the architectural analysis of explicit and implicit attributes in Haka historical architectures. On the basis of the concept of cultural inheritance, it is necessary to explore and research the protection and renewal of current historical buildings from the explicit and implicit aspects. Taking the Hakka architecture in Heyuan as an example, preservation and renewal strategies from the view of cultural inheritance theory are proposed, providing a practical reference for solving the problems that arise during historical building protection. Although external factors may influence cultural inheritance during the inheritance process, we must ensure that with complete cultural attributes and in line with the requirements of the times, we integrate diverse cultural inheritance to promote the effective continuation of cultural inheritance.
Principles and Practice of Landscape Design: An Application of Traditional Chinese Landscape Painting
Authors: Wenjing Liang , Nasir Nadia Mohd
Published: December 2023

As a unique artistic form, traditional Chinese landscape painting has aesthetic value and a close relationship with garden design. This study mainly explores the principles and practices of landscape design based on traditional Chinese landscape painting. Firstly, it introduces the brief history of the development of traditional Chinese landscape painting and its relationship with garden design. Then, it analyzes the characteristics of traditional landscape painting and garden design principles. Then, the application of traditional Chinese landscape painting in landscape design was analyzed, including landscape layout, plant selection, and matching, as well as the design of buildings and structures. In conclusion, applying traditional Chinese principles in modern landscapes presents inherent challenges that demand thoughtful consideration. As contemporary spaces evolve and adapt to changing needs, integrating traditional elements may face obstacles such as conflicting design philosophies, space constraints, and technological advancements. Addressing these challenges requires a nuanced approach that preserves the essence of traditional principles while accommodating the demands of modern living. This section explores strategies and innovative solutions to overcome these challenges and successfully apply traditional principles in the design of modern landscapes.
Design of the Mogao Caves Caisson and Its Application to Modern Interior Design
Authors: Jin Jiasheng , Sharudin Sharul Azim
Published: December 2023

Dunhuang Grottoes is one of the treasures of ancient Chinese art, famous for its exquisite murals and sculptures. The decorative patterns in the grottoes are rich and varied with brilliant colors, demonstrating the fusion of the cultures of the Central Plains and the Western Regions. The caisson motifs, in particular, are grand in scale and rich in variety, leaving a deep impression on people. These motifs complement the architectural structure of the grottoes, and together, they form a beautiful and harmonious artistic landscape. After China entered a fully industrialized society, the national culture of modern design in architecture became stronger and stronger, and caisson motifs are constantly being re-explored and applied to interior design. This study uses observational and case study methods to explore the relationship between traditional decorative motifs and modern design by examining the application of caisson motifs from the Mogao Grottoes in interior design. It is found that combining traditional caisson patterns with modern design is a feasible path, and the combination of traditional decorative elements and modern design, on the one hand, breaks the limitations of the current design, improves the aesthetic value and humanistic value of modern design works; on the other hand, it enriches the personality and emotion of the design works, enriches the expression of modern design, improves the overall image of modern design, and gives a new vitality.
Le théâtre de situations dans une formation à l’intégrité de responsables académiques
Authors: Bergadaà Michelle , Popescu Marian
Published: December 2023

De nombreux scandales ont entaché ces dernières années la réputation de l’université, alors même que la très grande majorité des chercheurs travaille de manière parfaitement intègre. Cette perte de crédibilité est dommageable, car l’université n’est pas un monde clos. Pourtant peu d’acteurs sont encore convaincus de l’urgence de mettre en place une véritable Responsabilité Sociétale Académique (RSA). Nous présentons dans cet article une nouvelle méthode de formation de ceux qui ont la responsabilité de veiller à l’intégrité au niveau individuel et/ou collectif. Les techniques théâtrales retenues permettent aux participants d’acquérir l’expérience et les connaissances conceptuelles et pratiques pour agir de manière optimale lorsque plusieurs « mondes » s’opposent. Nous avons sélectionné un cas emblématique pour illustrer ce besoin urgent, celui d’un conflit ouvert entre trois mondes : le monde académique dirigé par des professeurs seniors, celui de la société civile représentée par des observateurs bénévoles des phénomènes météorologiques et climatiques et celui des jeunes chercheurs. En fin de parcours, les participants-acteurs sont capables de comprendre les attitudes et les comportements des parties prenantes et de proposer des solutions satisfaisantes.
A háziállatok haemophagocytás histiocytás sarcomája : Irodalmi összefoglaló és esetbemutatók
Authors: Dobra Péter Ferenc , Szilasi Anna , Vajdovich Péter , Erdélyi Ildikó , Horváth Dávid Géza
Published: December 2023

A szerzők szakirodalmi adatok felhasználásával áttekintést nyújtanak a háziállatok haemophagocytás histiocytás sarcomájának előfordulásáról, kóroktanáról és kórfejlődéséről, ismertetik a megbetegedés klinikumát, patológiáját, valamint a diagnosztikai megközelítést és a kórjóslatot. A kórképhez kötődő, jellegzetes makroszkópos és mikroszkópos elváltozásokat saját eseteiket felhasználva szemléltetik. Ez az esetbemutatásokkal kiegészített szakirodalmi áttekintés rávilágít a kórkép, mint differenciáldiagnózis fontosságára háziállatok regeneratív anaemiája és thrombocytopeniája esetén.
PERLINDUNGAN HUKUM TERHADAP PEMBELI HAK ATAS TANAH MELALUI PEJABAT PEMBUAT AKTA TANAH SEMENTARA YANG TIDAK DIDAFTARKAN (STUDI PUTUSAN NOMOR 17/Pdt.G/2021/PN.Wat)
Authors: Untung Prasetia  , Widyarini Indriasti Wardani
Published: December 2023

Pendaftaran peralihan hak atas tanah yang dianut di Indonesia menggunakan sistem publikasi negatif yang mengandung unsur positif. Pendaftaran peralihan hak atas tanah melalui jual beli pada dasarnya untuk menjalankan asas publisitas untuk memberikan kepastian dan perlindungan hukum terhadap pembeli. Akan tetapi masih ada masyarakat yang tidak melakukan pendaftaran peralihan hak atas tanah tersebut. Penelitian ini bertujuan untuk mengetahui dan menganalisa perlindungan hukum terhadap pembeli hak atas tanah melalui Pejabat Pembuat Akta Tanah Sementara yang tidak didaftarkan, pertimbangan hakim didalam memutus perkara berkaitan dengan perlindungan hukum terhadap pembeli hak atas tanah melalui Pejabat Pembuat Akta Tanah Sementara yang tidak didaftarkan dalam Putusan Nomor 17/Pdt.G/2021/ PN.Wat, dan akibat hukum terhadap pembeli hak atas tanah melalui Pejabat Pembuat Akta Tanah Sementara yang tidak didaftarkan. Metode pendekatan yang dipergunakan dalam penelitian ini adalah penelitian normatif, spesifikasi penelitian yang digunakan dalam penelitian ini adalah deskriptif analitis, dengan menggunakan sumber data sekunder, yang diperoleh dari penelitian kepustakaan (library research), setelah data terkumpul akan dianalisis dan disistematisasikan secara kualitatif. Hasil penelitian ini menunjukkan bahwa (1) Pembeli tidak mendapatkan perlindungan hukum terhadap jual beli hak atas tanah melalui Pejabat Pembuat Akta Tanah Sementara yang tidak didaftarkan karena pembeli tidak mendapatkan surat tanda bukti kuat yang dikeluarkan oleh pemerintah berupa sertifikat tanah. Pembeli dapat memperjuangkan terhadap perlindungan dan kepastian hukum dengan mengajukan gugatan di Pengadilan (2) hakim memberikan pertimbangan hukum dengan melihat peristiwa hukum yang telah terjadi dengan dasar adanya Akta Jual Beli Nomor 62/2001 yang dibuat oleh Pejabat Pembuat Akta Tanah Sementara dan juga bukti-bukti yang diajukan para pihak dalam perkara tersebut. (3) Akibat hukum terhadap Pembeli yang tidak melakukan pendaftaran peralihan hak atas tanah yaitu pembeli tidak mendapatkan sertifikat tanah sebagai alat pembuktian yang kuat kepemilikan tanah.
PENGENAAN BPHTB DALAM PROSES JUAL BELI HAK ATAS TANAH DAN ATAU BANGUNAN DIBAWAH NJOP
Authors: Cahyo Adhi Nugroho
Published: December 2023

Penelitian ini dilatarbelakangi mengingat pentingnya tanah dan atau bangunan tersebut dalam kehidupan, maka sudah sewajarnya jika orang pribadi atau badan hukum yang mendapatkan nilai ekonomis serta manfaatdari tanah dan atau bangunan karena adanya perolehan hak atas tanah dan atau bangunan dikenakan pajak oleh negara. Pajak yang dimaksud adalah Bea Perolehan Hak atas Tanah dan atau Bangunan (BPHTB) dalam Undang-Undang Nomor 21 Tahun 1997. Penelitian ini bertujuan untuk mengetahui pengenaan pemungutan BPHTB terhadap transaksi jual beli Tanah dan atau bangunan dibawah nilai jual objek pajak (NJOP) di kota Semarang. Disamping itu, untuk mengetahui peranan Notaris/ PPAT dalam pengenaan pemungutan BPHTB. Serta mengetahui hambatan-hambatan yang timbul dan upaya yang dilakukan dalam mengatasi pemungutan BPHTB. Berdasarkan hasil penelitian menunjukkan bahwa Notaris/ PPAT termasuk sebagai salah satu pejabat yang mempunyai peranan penting dalam pelaksanaan pemungutan pajak Bea Pero!ehan Hak atas Tanah dan Bangunan (BPHTB). Dalam kehidupan bermasyarakat kadang-kadang KPPBB tidak mengetahui kejadian ataupun peristiwa yang harus dikenakan BPHTB, misalnya perolehan hak atas tanah dan bangunan karena jual beli. Seperti yang diketahui bahwa perolehan hak atas tanah dan atau merupakan objek yang dikenakan pajak BPHTB, maka untuk memperoleh data mengenai peristiwa jual beli tersebut perlu dijalin kerjasama dengan pihak Notaris/ PPAT. Notaris selain mempunyai wewenang dalam membuat akta yang otentik, juga mempunyai tugas dan tanggung jawab untuk memberikan bantuan penyuluhan hukum. Selain itu Notaris/ PPAT mempunyai kewajiban untuk pelaporan atau pemberitahuan perolehan hak atas tanah dan atau bangunan, berdasarkan ketentuan yang berlaku. Dalam PP No. 34 Tahun 1997- ditentukan bahwa Notaris/ PPAT harus melaporkan perolehan hak atas tanah dan atau bangunan setiap bulan.
Synthesis and evaluation of a rociletinib analog as prospective imaging double mutation L858R/T790M in non-small cell lung cancer
Authors: Fawwaz Muammar , Mishiro Kenji , Purwono Bambang , Nishii Ryuichi , Ogawa Kazuma
Published: December 2023

Context: Imaging the mutation status of non-small cell lung cancer (NSCLC) using radiolabeled tyrosine kinase inhibitor (TKI) analogs has garnered interest due to their unique interactions with the target epidermal growth factor receptor (EGFR). Rociletinib is a third-generation TKI that selectively inhibits the activated EGFR L858R/T790M mutations while sparing the wild-type EGFR. Aims: To synthesize a rociletinib analog for radioiodination purposes and evaluate its affinity for EGFR L858R/T790M using molecular docking and in vitro cytotoxicity assay. Methods: The rociletinib analog, N-{3-[(4-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidine-2-yl)amino] -5-iodophenyl} acrylamide (I-RMFZ), was produced by adding iodine into the diaminophenyl group and changing the position of the trifluoromethyl group. A simulation of molecular docking was conducted using the AutoDock Vina software suite. IC50 of I-RMFZ was determined using a cell cytotoxicity assay. Results: I-RMFZ was successfully synthesized through multistep reactions. Molecular docking revealed that I-RMFZ interacts with the EGFR L858R/T790M mutation. Cytotoxicity assay demonstrated that I-RMFZ had a high selectivity towards EGFR L858R/T779M mutation. Conclusions: I-RMFZ is notable for radioiodination and is anticipated to be comparable with in vivo features of rociletinib. Thus, I-RMFZ can potentially be developed as an imaging agent for NSCLC through preclinical assay.
Quantification of Humic Acid Produced in Worm-Activated Cast and Soil under Varied Land Use Types in Raebareli District
Authors: Singh Garima , Bhadauria Tuneera
Published: December 2023

The current study involves measuring the amount of humic acid produced by earthworms in their castings across five land uses, which were identified based on the level of anthropogenic activity along a disturbance gradient ranging from least disturbed protected forest to intensive agriculture to abandoned fallow to sodic ecosystem and then rehabilitated agroecosystem. Humic acids were recovered from typical soils and earthworm casts using the conventional alkali/acid fractionation method. According to the findings, humic acid obtained by casting has a significant advantage over humic acid derived from soil, which was directly impacted by the types of land use under consideration.
A Review on Chironomidae (Diptera) of the Eastern Himalayan Region: An Insight into Distribution and Conservation
Authors: Gurung Yuvraj
Published: December 2023

The Chironomidae (Diptera) commonly known as “midges”, are the most widely distributed and frequently the most abundant group of insects in freshwater ecosystems. Chironomids larvae plays a key ecological role in the maintenance of aquatic ecosystem services, mainly in secondary production and energy flow dynamics [1]. They are the freshwater bio-monitoring indicators of pollution, habitat modifications, and natural changes of water quality [2,3], and is a model which helps to predict diversity and strength of food web of aquatic communities [4]. The objective of the study is to highlight the distribution pattern, biodiversity and the status of conservation of Eastern Himalaya region species of the family Chironomidae. The 'Himalayan Biodiversity Hotspot' is indeed a "store house of biodiversity" because of its rich spectrum of species of flora and fauna including insect species which have been remaining unexplored. This study is a descriptive analysis to assay the main trends on Chironomidae research in freshwater assessments like ecology, palaeolimnology, biogeography, cytology, developmental and eco-toxicological research in Eastern Himalaya region. Finally the review work helps to get a more comprehensive picture of fauna of chironomids in the Eastern Himalayas in relation to those reported earlier from other parts of the globe.
Analysis of the Impact of Artificial Intelligence Prediction System on Private Security and Legislative Countermeasures
Authors:   The Korean Society of Private Security, Lee Hyeong Seok
Published: December 2023

This study analyzes the impact of prediction systems, a rapidly developing artificial intelligence technology, on the private security sector and suggests legislative responses. First, this study provides an overview of the formation process of AI prediction systems. This includes technical aspects such as machine learning, data processing, and algorithm development, as well as social and ethical contexts. Second, it analyzes the main characteristics of AI predictive systems and their application in the private security sector based on their effectiveness. In the process, the accuracy, speed, and level of automation of the system are discussed. Third, the positive and negative impacts of AI predictive systems on private security are assessed. Positive impacts include crime prevention, increased efficiency, and faster response times, while negative impacts include invasion of privacy, liability for errors, and job losses. Finally, based on these impacts, the study explores legislative responses, including clarifying the responsibility of AI prediction systems, strengthening privacy protection, and standardizing technology. This study highlights various issues that will inevitably arise as AI prediction systems are integrated into society and emphasizes the importance of a legal framework to address them. It also forecasts the long-term changes that the introduction of AI in the private security sector will bring, and proposes a legal framework for sustainable and fair technology utilization.
Characteristics and Countermeasures of Illegal Immigration and Emigration at Sea
Authors:   The Korean Society of Private Security, Cho Min-Sang
Published: December 2023

This study aims to discuss the need for enhancing the response system regarding illegal immigration and emigration through maritime routes. The research methodology involves analyzing literature and official data to explore the concepts and characteristics related to illegal immigration. Additionally, I attempted to make suggestions on recent changes in crime methods and countermeasures using press releases.
The summary of the characteristics and changes of illegal immigration and emigration are as follows.
First, the motivations and purposes behind illegal immigration and emigration are diverse. Second, within the context of environmental changes, illegal immigration techniques have diversified in terms of routes, means, and evasion tactics.
Suggestions regarding countermeasures against illegal immigration and emigration are as follows.
First, effective management requires understanding the root causes and motivations behind illegal immigration and emigration. Second, urgent development of surveillance and enforcement technologies is necessary. Third, regular updates and improvements to laws and regulations are essential. Fourth, establishing collaboration systems involving both domestic and international partners is crucial.
Gestión de capacidades para la competitividad empresarial en la industria restaurantera del estado de Colima
Authors: Rodríguez Guzmán Xiomara Clementina , Carrillo Jiménez Gustavo Adrián , Rivas Lozano María Alejandra , Castañeda Campos Bertha Lilia , Chávez Larios Jorge Alejandro
Published: December 2023

En este trabajo se investigó sobre la gestión del capital humano (GCH), la gestión de calidad (GC), las capacidades financieras (CF) y las capacidades dinámicas (CD), las cuáles son, de acuerdo a esta investigación, las variables que explican la competitividad empresarial. Los objetivos que se trazaron fueron: Identificar las capacidades internas que contribuyen a generar competitividad empresarial; Confirmar la relación que existe entre la gestión de las diferentes capacidades internas que le permiten a una empresa ser más competitiva; Establecer si las capacidades internas son predictoras de la competitividad empresarial en la industria restaurantera; Determinar la relación existente entre el tamaño, el tipo de restaurante y la antigüedad con las capacidades internas. Los sujetos de estudio fueron las unidades económicas dedicadas a la preparación de alimentos y bebidas para consumo inmediato, en restaurantes de autoservicio, restaurantes de comida para llevar y otros restaurantes con servicio limitado, establecidas en un lugar fijo (propio o rentado), con al menos 6 empleados y un año de antigüedad, ubicadas en el estado de Colima; y que por la especialidad y productos que ofrecen, los restaurantes se dediquen a la preparación de alimentos, servicio a la carta, comida corrida y cocinas económicas. En este sentido, mediante el modelo de ecuaciones estructurales, los autores confirmaron cómo las capacidades internas inciden en la competitividad empresarial de una empresa del sector restaurantero.