bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelo de Referência de Gerência de Configuração para um Processo Ágil de Reengenharia baseado em Framework
Authors: Ferreira Marliane Aldivina Oliveira , Cagnin Maria Istela
Published: July 2021

Gerência de Configuração (GC) é uma das maneiras de garantir a qualidade do software. Diversos modelos de qualidade que se preocupam com GC têm sido propostos, dentre eles destaca-se o modelo de referência MR- MPS. No entanto, há carência na literatura relacionada a modelos de referência no contexto de reengenharia. Sob essa perspectiva, este artigo tem como objetivo definir um modelo de referência de GC, denominado MR.GC-PARFAIT, para o processo ágil de reengenharia PARFAIT. O modelo foi definido por meio de três etapas (selecionar as atividades essenciais de GC, selecionar os artefatos essenciais de GC e estabelecer a aplicabilidade do modelo nas atividades do PARFAIT), sendo que nas duas primeiras etapas empregou-se o método GQM. A documentação do modelo é baseada na estrutura da documentação do RUP (Rational Unified Process) e está apresentada neste artigo.
PSPi – Melhorando Estimativas no Ambiente Corporativo
Authors: Reinehr Sheila , Burnett Robert , Pessôa Marcelo
Published: July 2021

Apesar da área de tecnologia da informação ter passado por diversas transformações nas últimas décadas, manter sistemas legados em mainframe é a realidade de muitas organizações. Ao mesmo tempo, estas empresas desejam usufruir dos benefícios proporcionados pelas novas tendências da engenharia de software que conferem mais visibilidade e previsibilidade ao desenvolvimento de software. Este artigo apresenta uma instância do método de estimativas do PSP (Personal Software Process) para ser aplicada ao ambiente corporativo mainframe e aos projetos que utilizam a linguagem COBOL.
Rastreabilidade do Conhecimento como Mecanismo de Melhoria de Qualidade de Software
Authors: de Mello Júnior Fernando Corrêa , Guedes Fabiana Costa , Pietrobon Carlos Alberto Marques
Published: July 2021

Os desenvolvedores de software manipulam uma grande variedade de conhecimento durante o processo de desenvolvimento de um software. Essa manipulação ocorre em todas as atividades. A manipulação adequada desse conhecimento auxilia na produção de software de maior qualidade e agiliza o ganho de experiência do desenvolvedor. Portanto, o objetivo deste estudo é uma proposta para capturar e recuperar conhecimento relativo ao desenvolvimento de software baseada na modelagem de metas, léxico e rastreabilidade de requisitos.
Uma Abordagem para Controle Estatístico do Processo e Gerência Quantitativa de Projetos
Authors: Cerdeiral Cristina , Mendes Sávio , Santos Gleison , Montoni Mariano , Pinto Rosângela , Rocha Ana Regina
Published: July 2021

O controle estatístico de processos é pré-requisito para apoio à melhoria contínua da qualidade e desempenho de processos. Muitas organizações buscam a melhoria de seus processos através desta prática, mas nem todas alcançam sucesso na sua aplicação. Uma das causas é aplicação incorreta do conhecimento estatístico necessário nas técnicas de análise. Este trabalho apresenta um exemplo de como controlar estatisticamente o processo e gerenciar quantitativamente os projetos, através da definição dos passos e técnicas a serem utilizadas, fornecendo conhecimento para organizações que desejem controlar estatisticamente seus processos na definição e execução dos passos e técnicas de análise.
Uma Proposta de Ferramenta para Execução Descentralizada de Processos de Software
Authors: Lima Adailton Magalhães , Reis Rodrigo Quites
Published: July 2021

Em projetos de desenvolvimento descentralizado de software existem problemas de comunicação e coordenação do processo de desenvolvimento, que frequentemente estão relacionadas com questões organizacionais dos envolvidos (clientes e fornecedores). Este trabalho descreve uma proposta para permitir a execução descentralizada de processos de software em um Sistema de Gestão baseado em Software Livre, relacionando as funcionalidades da proposta com os requisitos exigidos por modelos de maturidades de processos e por problemas citados pela literatura. Por fim, o texto aponta direções para pesquisa futura no tema.
Implantação de uma Metodologia de Testes em Iterações para um Grupo Independente
Authors: Diniz Renata C. C. , Ochner Juliana
Published: July 2021

Este artigo relata uma experiência de implantação de uma metodologia de testes em iterações para um grupo independente de testes. O objetivo do experimento foi utilizar os benefícios da abordagem iterativa para facilitar a definição e implantação de um processo completo de testes. Este processo foi definido com base na disciplina Testes da metodologia de desenvolvimento de software RUP, do padrão para artefatos de testes IEEE 829, das práticas definidas pelo TMM e pelas áreas de processo Verificação e Validação do CMMI. As iterações foram executadas conforme a prioridade e situação atual dos processos da equipe.
O caráter global da questão ambiental
Authors: Sanson Leandro Carvalho
Published: July 2021

Em um mundo onde as fronteiras se tornaram mais flexíveis, e a velocidade de informações aumenta exponencialmente, novas questões e novos atores assumem protagonismo no cenário internacional. Nesse contexto, os Estados passaram a responder a novos desafios cujos impactos não podem mais ser deixados para segundo plano, tanto no âmbito local quanto no global, como, por exemplo, a degradação ambiental. Neste sentido, buscou-se no presente estudo analisar estes processos de transformações e impactos nas relações sociais e políticas no ambiente do mundo globalizado, considerando aspectos referentes ao papel do Estado e sua relação com a sociedade civil, partindo de elementos como democracia e meio ambiente, bem como, a constituição e dinâmica de uma esfera pública da questão ambiental.
Os centros do poder econômico mundial na atualidade e as possibilidades de conflitos regionais
Authors: Vescovi Luiz Fernando
Published: July 2021

A presente pesquisa tem por intuito investigar as fontes primordiais de poder econômico mundial da atualidade, sob um enfoque geopolítico e das relações internacionais contemporâneas, e que detenham representatividade nas questões político-econômicas e administrativas de poder do globo, tendo por análise, também, as possibilidades de conflitos regionais decorrentes do crescimento destes centros. Tem por escopo, ainda, traçar, em linhas gerais, as evidências fáticas que este poder econômico mundial possa vir a ensejar num futuro internacional próximo, pelas relações que acontecem entre os Estados e pelos interesses que expressam, no cenário mundial.
Os conflitos contemporâneos e a teoria de Sun Tzu: novas abordagens, antigos postulados
Authors: Matos Sergio Ricardo Reis , De Souza Marcelo Bastos , Perezino Paulo Eduardo De Mello
Published: July 2021

O cenário internacional da atualidade apresenta-se bastante complexo, notadamente a partir da década de 1990, com a derrocada da União Soviética e a consequente quebra da ordem mundial bipolar. Ainda assim, a transformação dos Estados Unidos da América na única superpotência mundial não trouxe a paz esperada ao sistema internacional, verificando-se o surgimento de diversos conflitos. Os Estados passaram a adaptar suas estratégias militares às demandas advindas dessa nova conjuntura. Nesse contexto, o presente trabalho tem por objetivo geral analisar a aplicabilidade da teoria da guerra proposta por Sun Tzu aos conflitos contemporâneos. Para alcançar esse fim, foram traçados os seguintes objetivos específicos: estudar os conceitos e as estratégias conexas às abordagens abrangentes dos conflitos contemporâneos; estudar a escola estratégica chinesa, destacando a teoria da guerra de Sun Tzu; discutir as aproximações dos postulados de Sun Tzu aos conflitos contemporâneos. Utilizou-se uma abordagem qualitativa, valorizando a epistemologia da complexidade. As categorias estudadas foram: estratégia indireta; conhecimento do inimigo; dissimulação e previsão; tempo; preparação do campo de batalha e liderança. A revisão da literatura foi feita por meio de pesquisa bibliográfica. A discussão compreende a análise de conteúdo e a triangulação das entrevistas e de textos dos novos conflitos. Por fim, pôde-se constatar a validade e a aplicabilidade das teorias de Sun Tzu aos conflitos contemporâneos, tornando sua obra uma leitura recomendada para qualquer estrategista do século XXI.
Junho de 2013 e os sinais de uma crise
Authors: Ferraz da Silveira José Renato , Dall'Agnol Augusto César
Published: July 2021

Este trabalho busca compreender quais foram as dinâmicas que permearam o movimento Vem pra Rua em junho de 2013. Entende-se, então, que houve uma crise de mediação política no Brasil e que os partidos políticos já não se constituiriam em entidades com credibilidade perante a sociedade. Neste sentido, utiliza-se aqui do método dedutivo e da revisão bibliográfica acerca de quatro questões que se correlacionam ao longo do artigo: i) junho de 2013; ii) tragédia da política; iii) poder, Estado e legitimidade e; iv) crise política e vulnerabilidade dos partidos, a fim de compreender o sentido de governabilidade, governança, legitimidade e credibilidade no contexto do movimento de junho de 2013. Por fim, conclui-se que houve catarse, ou seja, um enfraquecimento do ímpeto para a ação sem ter-se concluído o ato, ou tendo-se concluído apenas um ato que não chega a alterar fatores significativos.
Perspectivas da luta guerrilheira armada paraguaia: uma revolução socialista possível no século XXI?
Authors: Bourscheid Junior Ivan
Published: July 2021

O presente artigo intenta apresentar e analisar as perspectivas e desafios ao movimento guerrilheiro Ejército del Pueblo Paraguayo (EPP), em sua tentativa de implantação de uma revolução socialista no Paraguai. Para tanto, são expostas e debatidas as incapacidades do Estado paraguaio na promoção de mudanças sociais que lançassem as bases para a superação das históricas assimetrias sociais, sua manutenção com o advento da democracia na década de 1990, dificultando a legitimação e a representatividade do regime, e fazendo com que se fomentasse a eclosão do movimento revolucionário, e posteriormente da guerrilha armada do século XXI. Por meio do aporte leninista – fundamento utilizado pelo EPP – busca-se compreender a ação do EPP e consequentemente analisar suas possibilidades de êxito como organização revolucionária. Da mesma forma, contemplam-se os desafios postos à ação guerrilheira, tanto de ordem interna da organização, quanto de ordem externa. Por conseguinte, considera-se que a utilização da violência revolucionária não alcançará seus objetivos, cabendo à conscientização revolucionária de classe e à democracia de massas o papel central em um processo de implantação do socialismo.
Crise migratória: uma análise sobre direitos humanos e os refugiados sírios
Authors: Ernst Kelly Patrícia
Published: July 2021

O presente artigo tem por objetivo analisar a questão de respeito aos direitos humanos dos refugiados sírios, partindo de análise anterior e posterior ao status de refugiado. Inicialmente, aborda-se a origem do conflito armado na Síria, e as consequências aos seus cidadãos, os quais tem buscado proteção internacional nos países vizinhos e Europa. Em seguida, analisam-se as políticas internacionais adotadas para os refugiados e os impactos nos países de destino. Por fim, aborda-se a temática dos direitos humanos, garantidos por leis e estatutos internacionais, a todos aqueles que buscam proteção sob o status de refugiado. Dessa forma, visa-se averiguar de que forma os direitos fundamentais dos cidadãos sírios foram ameaçados ou violados por seu país de origem e as políticas internacionais adotadas em prol dos refugiados sírios.
O mito de Jano: as duas faces da ordem pública no Direito Internacional Privado
Authors: De Faria Barbosa Pedro Henrique , Loreto Sylvio
Published: July 2021

O presente artigo insere-se no campo de estudo do Direito Internacional Privado, focando-se na análise da atual natureza da ordem pública. Seu objetivo principal é a análise das ordens públicas nacional e internacional, considerando se as mesmas são conceitos excludentes ou convergentes. Tal abordagem é desenvolvida por meio de uma interpretação metafórica da conexão entre os conceitos de ordem pública e o mito da divindade romana Jano. Primeiramente, é feita uma análise acerca da formulação do conceito de ordem pública nacional num âmbito jurídico-histórico, considerando as definições legais trazidas nas normas internacionais e nacionais. Em seguida, versa sobre a possibilidade de conceituação de uma ordem pública internacional e quais seriam as fontes da mesma. Este estudo aponta para conclusões no sentido da necessidade de interpretações que garantam a coexistência entre as duas modalidades de ordem pública e a garantia do respeito ao Direito Internacional Privado e aos direitos nacionais.
A complexidade do conflito ambiental internacional e a mediação de conflitos. A atuação da Unidade de Apoio à Mediação da ONU
Authors: Santos Juliano Locatelli
Published: July 2021

O presente estudo trata das características e peculiaridades do conflito ambiental, destacando os diversos aspectos que o permeiam e os interesses em disputa quando se trata de relações internacionais, ou ainda de conflitos internos no âmbito dos países. Através do relato de dois casos específicos em que melhor se podem captar algumas das características e vicissitudes típicas do conflito que envolve o meio ambiente, extraem-se alguns dos aspectos mais presentes no conflito ambiental. Por fim, a partir das características apuradas nestes casos específicos, passa-se a tratar do modo como atualmente está constituída a Unidade de Apoio à Mediação das Nações Unidas, enquanto a experiência concreta melhor formulada a nível global para o tratamento do conflito ambiental e suas particularidades. Metodologicamente, o estudo se vale da pesquisa bibliográfica e documental dedutiva e do estudo de caso, concluindo pelo entendimento de que na atualidade as Nações Unidas contem com uma estrutura de múltipla abordagem, melhor apropriada para o tratamento dos conflitos ambientais regionais e transnacionais.
Primera República española: Análisis normativo sobre aspectos de ceremonial y protocolo
Authors: Mesa Göbel José Manuel
Published: July 2021

La Primera República española, se va a caracterizar por ser un período histórico breve de escasamente un año, dentro del denominado Sexenio democrático en la historia de España. Como nuevo régimen político, en este caso una república y sin entrar a valorar de forma completa en las etapas de la misma, el ceremonial y protocolo, se convierten una vez más en un elemento esencial y fundamental de legitimación del nuevo régimen político, al igual que sucede en etapas anteriores del sexenio democrático, donde la configuración de eventos, la derogación y creación de normas amoldan el sentido que desde ese punto de vista el régimen político que se establece quiere configurar. Se trata de un breve análisis de aquellas disposiciones que aparecen recogidas en la Gaceta de Madrid durante la Primera República y otras consideraciones llevadas a cabo por parte de la acción de los distintos gobiernos en ese corto periodo de tiempo.
A large and pedunculated inflammatory pseudotumor with pseudosarcomatous change of the cecum mimicking a malignant polyp: a case report and literature review
Authors: Oh Jong Suk , Kim Hyung Wook , Park Su Bum , Kang Dae Hwan , Choi Cheol Woong , Kim Su Jin , Nam Hyeong Seok , Ryu Dae Gon
Published: July 2021

Inflammatory pseudotumor (IPT) is a rare benign tumor of unknown etiology that can occur in almost any organ system. It has neoplastic features such as local recurrence, invasive growth, and vascular invasion, leading to the possibility of malignant sarcomatous changes. The clinical presentations of colonic IPT may include abdominal pain, anemia, a palpable mass, and intestinal obstruction. A few cases of colonic IPT have been reported, but colonic IPT with pedunculated morphology is very rare. Furthermore, since it can mimic malignant polyps, understanding the endoscopic findings of colonic IPT is important for proper treatment. Herein, we present a case of colonic IPT with pseudosarcomatous changes, presenting as a large polyp, mimicking a malignant polyp in the cecum, along with a literature review.
Freeze-dried bovine amniotic membrane as a cell delivery scaffold in a porcine model of radiation-induced chronic wounds
Authors: Oh Daemyung , Son Daegu , Kim Jinhee , Kwon Sun-Young
Published: July 2021

Background Locoregional stem cell delivery is very important for increasing the efficiency of cell therapy. Amnisite BA (Amnisite) is a freeze-dried amniotic membrane harvested from bovine placenta. The objective of this study was to investigate the retention of cells of the stromal vascular fraction (SVF) on Amnisite and to determine the effects of cell-loaded Amnisite in a porcine radiation-induced chronic wound model.Methods Initially, experiments were conducted to find the most suitable hydration and incubation conditions for the attachment of SVF cells extracted from pig fat to Amnisite. Before seeding, SVFs were labeled with PKH67. The SVF cell-loaded Amnisite (group S), Amnisite only (group A), and polyurethane foam (group C) were applied to treat radiation-induced chronic wounds in a porcine model. Biopsy was performed at 10, 14, and 21 days post-operation for histological analysis.Results Retaining the SVF on Amnisite required 30 minutes for hydration and 1 hour for incubation. A PKH67 fluorescence study showed that Amnisite successfully delivered the SVF to the wounds. In histological analysis, group S showed increased re-epithelialization and revascularization with decreased inflammation at 10 days post-operation.Conclusions SVFs had acceptable adherence on hydrated Amnisite, with successful cell delivery to a radiation-induced chronic wound model.
Reducing pain and opioid consumption after body contouring of the breast by application of a perioperative nerve block: a systematic review
Authors: Asserson Derek B. , Sahar David E.
Published: July 2021

Background Pain in the postoperative body contouring patient has traditionally been managed with narcotic medication. In an effort to minimize side effects and prevent addiction, plastic surgeons are searching for novel ways to provide adequate analgesia, one of which is nerve blocks. This study was conducted with a meta-analysis that evaluates the efficacy of these blocks for patients who undergo breast surgery.Methods A search of the PubMed/MEDLINE database for articles including the terms “postoperative analgesia” OR “postoperative pain management” AND “in plastic surgery” OR “in cosmetic surgery” OR “in elective surgery” in February 2019 generated five studies on elective breast augmentation and reduction mammoplasty that reported pain scores and quantities of opioids consumed. Independent samples t-tests, one-way analysis of variance, and a random effects model were implemented for evaluation.Results A total of 317 patients were identified as having undergone body contouring of the breast, about half of which received a nerve block. Pain scores on a 1–10 scale and opioid dose-equivalents were calculated. Those who were blocked had an average score of 2.40 compared to 3.64 for those who did not (P<0.001), and required an average of 5.20 less narcotic doses (P<0.001). Pain relief following subpectoral augmentation was best achieved with type-II blocks as opposed to type-I and type-II with serratus plane (P<0.001).Conclusions The opioid epidemic has extended to all surgical specialties. Implementation of a nerve block seems to be an efficacious and cost-effective mechanism to not only help with postoperative pain, but also lower the need for narcotics, especially in subpectoral augmentation.
Standard errors and significance testing in data analysis for testing classifiers
Authors: Wu Jin Chu , Kacker Raghu N
Published: July 2021

The one-classifier and two-classifier significance testing for evaluation and comparison of classifiers are conducted to investigate the statistical significance of differences and provide quantitative information in terms of the significance level, i.e., p-value, in a new ROC analysis where three score distributions and two decision thresholds are employed, and data dependency caused by multiple use of the same subjects is involved. To analyze the performance of classifiers, the standard error of the cost function is estimated using the nonparametric three-sample two-layer bootstrap algorithm on a two-layer data structure constructed after dataset optimization, based on our prior rigorous statistical research in ROC analysis on large datasets with data dependency. In comparison, the positive correlation coefficient must be taken into consideration, which is computed using a synchronized resampling algorithm; otherwise, the likelihood of detecting the statistical significance of difference between the performance levels of two classifiers can be wrongly reduced.
The function of health promotion ofces in early detetcion and prevention of melanoma
Authors:   Doctoral School of Health Sciences  University of Debrecen, Szörényiné Ványi Gabriella , Battyáni Zita , Vass Bence Attila , Moizs Mariann , Repa Imre
Published: July 2021

The standardized incidence of melanoma almost doubled in Hungary. Incidence and mortality of melanoma could be reduce by prevention and early detection. The frst health promotion ofces as actors in Public Health appeared in 2008. The authors present their good practices and possible programs of melanoma prevention through the experience of their health promotion ofce. Their study revealed that prevention should place greater emphasis on individual risk factors, estimated risk, and sun protection. Particular attention should be paid to the prevention of sunburn in childhood, and more men and those with lower levels of education should be able to take advantage of the possibility of skin examination.
Alteration among the patch test allergens in the environmental standard baseline series of the Allergology Laboratory of the National Dermatological and Venereological Institute and the Department of Dermatology, Venereology and Dermatooncology of Semmelweis University
Authors:   Department of Dermatology, Venereology and Dermatooncology Semmelweis University, Faculty of Medicine, Németh Dominik
Published: July 2021

The patch test has been the standard diagnostic tool of verifying contact hypersensitivity for decades. The test’s methodological elements and the tested allergen groups are the achievements of a dynamically changing process of the 20th century. Most commonly, the environmental standard baseline series is used in everyday clinical practice. Te frst environmental series in Hungary, which was recommended for national use, was created in the Allergology Laboratory of the National Dermatological and Venereological Institute in the 1970 years. It consisted of 21 allergens. Afer the Institute’s closure, the Semmelweis University, Department of Dermatology, Venereology and Dermatooncology continued to perform the patch testing. Te number of the baseline series members became more than doubled by now. This review aims to summarise the alterations in the environmental standard baseline series of the Allergology Laboratory of the National Dermatological and Venereological Institute and the Department of Dermatology, Venereology and Dermatooncology of the Semmelweis University and the sensitisation frequencies registered from 1976 to 2016 per 10 year periods.
Cutaneous manifestations of COVID-19
Authors:   Department of Dermatology and Allergology Albert Szent-Györgyi Medical Center University of Szeged, Nagy Géza Róbert , Bata-Csörgő Zsuzsanna , Kemény Lajos
Published: July 2021

There has been increasing number of reports on the cutaneousmanifestations of COVID-19 patients. The skin involvements in patients with COVID-19 demonstrate various clinical entities. In our article, we summarize these cutaneous manifestations based on the literature data and on our own experiencies. While in inducing maculopapulosus exanthem, urticaria, erythema multiformeand vesicular lesions etiological factors other than SARS-COV-2 virus may play a role , vascular manifestations, such as chilblain-like lesions and retiform purpura, could have a more direct association with the virus. Cutaneous manifestation may help in identifying asymptomatic patients and could provide prognostic information on the clinical course of COVID-19.
Age-specific incidence of herpes simplex infection in the light of clinical appearance
Authors:   University of Pécs Medical School Department of Dermatology, Venereology and Oncodermatology, Csernus Adriána Evelin , Rózsa Annamária , Gyulai Rolland
Published: July 2021

Herpes simplex virus (HSV) infection is extremely common in both children and adults. HSV has two serotypes, HSV-1 primarily causes orolabial while HSV-2 anogenital symptoms. In recent decades there has been a change in the predilection to affected anatomical regions in both serotypes, participation of HSV-1 serotype in genital infections is increasing. The primary acquisition of HSV-1 has increasingly shifted from early childhood to young adulthood over the past years. Asymptomatic infection and virulence factors are crucial in the spread of the virus. Cutaneous symptoms, erosions and crusted lesions after vesicular stage present various differential diagnostic problems in the involved regions. Early diagnosis and timely adequate therapy in serious cases are essential as well as suppressive treatment of recurrent symptoms. Several clinical trials are underway to develop more effective antivirals. Vaccination against HSV would be a key to prevent latent infections, transmission and reactivation. The authors present characteristics of HSV, age-specific clinical manifestations, differential diagnostic problems and adequate treatment strategies.
Cutaneous lupus erythematosus, skin or systemic autoimmune disease?
Authors:   Department of Dermatology, Venereology and Dermatooncology Semmelweis University, Faculty of Medicine, Hidvégi Bernadett , Király Zsófia , Marschalkó Márta
Published: July 2021

The authors present the different clinical forms of cutaneous lupus erythematosus and their prognostic relevance, along with discusson of the uncommon subtypes of the disease. Furthermore, in addition to the lupus specific cutaneous symptoms, the nonspecific cutaneous manifestations are also reviewed. The newest diagnostic criterias and the EDF therapeutic guideline are summarized.
Systemic sclerosis and localized scleroderma: Where are we now?
Authors:   Department of Dermatology, Venereology and Dermatooncology Semmelweis University, Faculty of Medicine, Bali Gábor , Hidvégi Bernadett , Sárdy Miklós
Published: July 2021

Systemic sclerosis is a collagen vascular disease which could lead to fibrosis of the skin and internal organs. It is characterized by a high disease burden and mortality. The 2013 classification criteria system helps to recognize the disease early, which allows prompt intervention and a better survival. In the past few year the recognition of the association between the presence of RNA polimerase III antibodies and malignancies was important. Treatment options of SSc have been improved. Early, intensive immunosuppressive treatment (cyclophosphamide, mycophenolate mofetil) of interstitial lung disease inhibits progression. There are several treatment modalities for the treatment of pulmonary arterial hypertension and digital ulcers (endothelin receptor antagonists, phosphodiesterase 5 inhibitors, prostaglandin analogues). Antifibrotic drugs (nintedanib, riociguate) are also available among former immunosuppressive and vasoactive agents. Lenabasum is a new promising selective cannabinoid receptor 2 agonist, which inhibits inflammation and fibrosis. Localized scleroderma presents a diverse clinical picture. The disease leads to fibrosis of the skin but it is not accompanied with serious inner organ involvement typically seen in systemic sclerosis. Capillaroscopy abnormalities, sclerodactyly and SSc specific antibodies are absent in localized scleroderma . The 2017 EDF guideline formulates a very useful classification, checkup and treatment recommendations.
Vasculitis involving the skin
Authors:   Department of Dermatology and Allergology Albert Szent-Györgyi Medical Center University of Szeged, Belső Nóra , Nagy Géza , Bata-Csörgő Zsuzsanna
Published: July 2021

Here we summarize vasculitides involving the skin. Among cutaneous vasculitides there are three major groups, one is a systemic vasculitis with cutaneous involvement, another a systemic vasculitis with skin limited appearance, and the last group is a single organ vasculitis, that only affects the skin. We summarize the importance of the proper diagnosis in this heterogeneous group based on both clinical and histopathologic examinations, and present information on the complex underlying pathology
Las políticas de emprendimiento en México
Authors: Contreras Cueva Angélica Beatriz , Macías Álvarez Pamela , González-Morales Olga
Published: July 2021

El presente estudio tiene como objetivo analizar la tendencia de las condiciones del entorno nacional en México que inciden en la actividad emprendedora, para identificar si existen condiciones propicias para fortalecer el emprendimiento y contribuir al desarrollo económico del país. La investigación toma como base la opinión de expertos que genera el Global Entrepreneurship Monitor (GEM) (2016-2017) sobre la situación que enfrentan los emprendedores, como referencia para influir sobre las políticas públicas para el emprendimiento. La metodología utiliza el análisis de correspondencias, que permite analizar datos categóricos y detectar estructuras subyacentes en un conjunto de datos, con ello describir aspectos sobre la opinión de los expertos. Con los promedios, se analiza el nivel de valoraciones de las condiciones que determinan el emprendimiento y se comparan resultados de México con el estado de Jalisco. Entre los resultados destaca la necesidad de diseñar e implementar políticas públicas relacionadas con tasas de impuestos, regulaciones y programas que fomenten el espíritu emprendedor para fortalecer los negocios y su consolidación. Dentro del sistema educativo superior se fomenta la creatividad y la innovación, no así en los niveles de primaria y secundaria, por lo que requiere su fortalecimiento para impulsar una cultura emprendedora promotora del empleo y del crecimiento económico.
Editorial
Authors: Domínguez Martí
Published: July 2021

Science continues to face new challenges every day. Climate change, ensuring sustainable agriculture, opening up new ethical debates about genetic practices, the use of new digital spaces and information, etc. The first thematic monograph in this new volume of Mètode Science Studies Journal tackles our society’s most urgent challenges in building a sustainable future.
And yet another challenge is the focus of another one of the monographs contained in this volume: understanding the complexity of our planet’s current biodiversity. Evolution is key to solve this question. These pages present us with different scenarios that help us to better understand how to tackle the new challenges faced by our planet’s species.
However, addressing scientific challenges is not only about hoping for a bright future, but also about looking back and learning from our mistakes. Science has much to say about our memory; it can help us to better understand how we got here, and to successfully close episodes of our history. Learning about how the Commonwealth recovers and identifies the remains of fallen WWI soldiers might help us understand the outstanding debt that we owe to our own historical memory. Through the different articles in this monograph, we discuss how much forensic science can tell us about our history, from Roman times to the Spanish Civil War.
After all, our past can reveal a great deal about our present and help us to understand exactly what challenges we face as scientists and as a society. That is why the issue devoted to the relationship established between scientists and the Nazi regime in the first half of the twentieth century is especially significant. What did the purges carried out by the Nazis mean for science? To what extent did the scientific community look the other way? Did they even take advantage of the situation? What was the relationship between Nazi ideals and some scientific postulates?
The historian Christian Ingrao reminds us in his opening article that the vast majority of university professors (99% of them) continued working in Nazified institutions. If we are to solve current and potential challenges hoping for a better future, we must take a look at the past and learn both from the lighter and the darker shades of science.
In praise of life. The dynamic concept of biodiversity
Authors: Mesquita-Joanes Francesc
Published: July 2021

We humans have long been aware that as a species we have great power to modify the natural world. We sure have. But it has only been a few decades since society, with a firm voice, turned against the destruction carried out in the past. We want to preserve the variety of life forms in all their beauty and complexity, because this biological variety not only provides us physical support, but also promotes our intellectual and philosophical development. It makes us wonder how it emerged, how it works, why species differ from place to place…
El concepto en Kant y en Hegel. La relación entre forma transcendental y forma absoluta
Authors: Sepúlveda Zambrano Pedro
Published: July 2021

Este artículo examina el concepto del concepto en Kant y en Hegel. El modo de relación entre el principio de la apercepción y el concepto puro permite pensar a la filosofía de la forma transcendental como una metafísica crítica. La conexión sistemática entre las doctrinas del concepto, el juicio y el silogismo posibilita, en cambio, concebir la filosofía de la forma absoluta como una metafísica especulativa. En ambas lógicas el objeto corresponde, en último término, a la totalidad de las determinaciones de aquella unidad suprema que Kant denominó apercepción y Hegel el concepto.
Normas para autores
Authors: . Equipo Editorial
Published: July 2021

Normas
Using of n-grams from morphological tags for fake news classification
Authors: Kapusta Jozef , Drlik Martin , Munk Michal
Published: July 2021

Research of the techniques for effective fake news detection has become very needed and attractive. These techniques have a background in many research disciplines, including morphological analysis. Several researchers stated that simple content-related n-grams and POS tagging had been proven insufficient for fake news classification. However, they did not realise any empirical research results, which could confirm these statements experimentally in the last decade. Considering this contradiction, the main aim of the paper is to experimentally evaluate the potential of the common use of n-grams and POS tags for the correct classification of fake and true news. The dataset of published fake or real news about the current Covid-19 pandemic was pre-processed using morphological analysis. As a result, n-grams of POS tags were prepared and further analysed. Three techniques based on POS tags were proposed and applied to different groups of n-grams in the pre-processing phase of fake news detection. The n-gram size was examined as the first. Subsequently, the most suitable depth of the decision trees for sufficient generalization was scoped. Finally, the performance measures of models based on the proposed techniques were compared with the standardised reference TF-IDF technique. The performance measures of the model like accuracy, precision, recall and f1-score are considered, together with the 10-fold cross-validation technique. Simultaneously, the question, whether the TF-IDF technique can be improved using POS tags was researched in detail. The results showed that the newly proposed techniques are comparable with the traditional TF-IDF technique. At the same time, it can be stated that the morphological analysis can improve the baseline TF-IDF technique. As a result, the performance measures of the model, precision for fake news and recall for real news, were statistically significantly improved.
MALDI-TOF MS as a method for rapid identification of Phytophthora de Bary, 1876
Authors: Božik Matěj , Mrázková Marcela , Novotná Karolína , Hrabětová Markéta , Maršik Petr , Klouček Pavel , Černý Karel
Published: July 2021

The number of described species of the oomycete genus Phytophthora is growing rapidly, highlighting the need for low-cost, rapid tools for species identification. Here, a collection of 24 Phytophthora species (42 samples) from natural as well as anthropogenic habitats were genetically identified using the internal transcribed spacer (ITS) and cytochrome c oxidase subunit I (COI) regions. Because genetic identification is time consuming, we have created a complementary method based on by matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS). Both methods were compared and hypothesis that the MALDI-TOF MS method can be a fast and reliable method for the identification of oomycetes was confirmed. Over 3500 mass spectra were acquired, manually reviewed for quality control, and consolidated into a single reference library using the Bruker MALDI Biotyper platform. Finally, a database containing 144 main spectra (MSPs) was created and published in repository. The method presented in this study will facilitate the use of MALDI-TOF MS as a complement to existing approaches for fast, reliable identification of Phytophthora isolates.
Assessment of agro-morphological, physiological and yield traits diversity among tropical rice
Authors: Kakar Naqeebullah , Bheemanahalli Raju , Jumaa Salah , Redoña Edilberto , Warburton Marilyn L. , Reddy Kambham R.
Published: July 2021

Rice (Oryza sativa L.) is an essential staple food crop, but the per acre average rice yield is less than its substantial potential in many countries. Rice breeders and growers would benefit from a robust genotypes with better morpho-physiological and yield-related traits. Here, seventy-four new rice genotypes were phenotyped over two years for their gas exchange and yield potential-related traits under Mississippi rice-growing conditions. A wide range of variability was observed among genotypes for all measured traits. Detailed phenotyping of rice genotypes revealed two key relationships that function together to contribute to yield potential under the southern US climate. The first one, grain yield, grain number, and spikelet fertility, showed considerable correlation (r = 0.45 to 0.79, p < 0.001) to harvest index. Conversely, days to anthesis had a high and negative correlation with harvest index (r = −0.79, p < 0.001), which suggests that selection for short duration genotypes with efficient partitioning could improve the yields under southern US climatic conditions. Additive response index revealed a higher positive association with yield traits (R2 = 0.59) than physiological (R2 = 0.28) and morphological traits (R2 = 0.21). Compared with the commercial genotype Rex, 21.6% and 47.3% of the rice genotypes had a higher gas exchange and yield response scores. IR08A172, IR07K142 and IR07F287 were ranked as high performers in physiological and yield response indices. Our study highlights that selection for short-duration yield-related traits with efficient sink capacity traits is desirable for future breeding programs.
Virtual fencing as a wildlife-vehicle collision mitigation measure: technical function, wildlife response and considerations for installation in an urban environment
Authors: Reeves Julie , Burnett Scott , Brunton Elizabeth
Published: July 2021

Virtual wildlife fencing presents as a cost-effective measure for roadkill mitigation, which aids in reducing fragmentation of wildlife populations by facilitating safer movement of wildlife across the landscape. In this study, we conducted an audit of a virtual fence installation in south-east Queensland, Australia. We assessed its reliability in flows of traffic and the effect that installation parameters and site conditions had on its effective operation in an urban setting. We made observations on the behavioural response of Eastern Grey Kangaroos Macropus giganteus to the acoustic signals produced by the fence. We found that the fencing activated consistently in response to headlights at dusk and dawn, and when traffic flows were dense, despite considerable variations in the range of installation parameters. However, we identified that the response of the virtual fence to headlights was affected by road curvature and we identified inconsistencies in the timing and pattern of activation in response to traffic. Behavioural observations showed a significant increase in kangaroo vigilance in response to the acoustic signal of the fence when resting or grazing, and kangaroos detected the acoustic signal up to 50 m away. While virtual fencing operates effectively and is a low-cost roadkill mitigation option that can be applied to the urban environment, more research is needed to better understand the effect of its acoustic and visual signals on wildlife behaviour and efficacy in busy urban environments.
Quality Evaluation of Different African Catfish (Clarias gariepinus) Meat Pickles during Storage
Authors: Abdel-Mobdy H. E. , Abdel - Aal H. A. , Souzan S. L. , Nassar A. G.
Published: July 2021

Fish pickles (made with tomato juice, vinegar, and lemon juice) were made from catfish (Clariasgariepinus) and their nutritional quality were evaluated. The quality of the vinegar pickle was excellent, and the quality of the lemon and tomato juice pickle was satisfactory. The  moisture  content  of  the  pickle  products  ranged  from    67.32  to 67.58%  (Treatment 1 = with  vinegar),  66.60  to  67.03%  (Treatment 2= with  tomato  juice  ),  and  67.18  to  67.55  % (Treatment 3= with lemon juice) up to 90 day storage at ambient temperature. The protein and lipid contents  of  pickle  with  vinegar,  tomato  juice  and  lemon  juice    were  ranged  from  (16.91-16.38  and  13.46-13.78),  (18.01-17.68  and  13.46-13.85)  and  (16.72-16.43  and 13.62-13.97%), respectively; ash content in all sample pickling was ranged from (0.98 to 1.30%). The quality of catfish pickles stored at room temperature was found to be acceptable for consumption after 90 days.
The Impact of Trade Openness on Trade and Tax Revenues in Nigeria (1981-2018)
Authors: Anyalewechi Abaneme, Arthur , Adegbemi Onakoya,
Published: July 2021

The challenge to provide enough resources to fund infrastructure development has been the bane of most developing countries like Nigeria. The appropriate economic and trade policies to deploy to increase revenue generating capacity of the government become compelling. This study examined the impact of trade openness on trade and tax revenue in Nigeria between 1981 and 2018. The study employed Augmented Dickey Fuller and Phillip Peron tests to conduct the stationarity tests. Akaike Information Criterion and Final Predictor Error provided the best lag lengths. Johansen cointegration test was used to determine the long run relationship. The study employed Vector Error Correction Model for the regression analysis while T- test and F test were also done to confirm the statistical significance of the variables and the models. For autocorrelation problem, Breusch-Godfrey serial correlation LM test were conducted and other post- estimation tests were also used. The result of the study showed that trade openness was negatively related with total tax revenue and with trade tax revenue (CED). The results indicate that a unit increase in trade openness leads to 11.58% decrease in trade revenue from CED and 13.69% decrease in total revenue. Trade openness as a policy to increase tax revenue was not beneficial to the country. Trade openness should be adopted with manufacturing and productive sector orientation in mind. In addition, tariff rates should be reviewed, and the tax structure should be transparent, and judicious use of tax resources should be implemented by government.
Composition of Volatile Flavor Compound on Fresh Asian Redtail Catfish
Authors: Asri Sofie Widya , Pratama Rusky Intan
Published: July 2021

The purpose of this research was to identify the composition of volatile flavor compound of asian redtail catfish (Hemibagrus nemurus). The method of this research was experimental method of fresh sample. The extraction sample method in this research was Solid Phase Microextraction (SPME) and used Gas Chromatography-Mass Spectrometry (GC/MS) to detect the compound on the sample. The volatile flavor compound were successfully detected with total 23 compounds on fresh sample and mostly the compounds were derived from hydrocarbons, aldehyde, alcohols, ketones, ester, and others. The highest proportion that detected was hexanal compound (26,78%) The proximate analysis was also identified. The result of proximate analysis on fresh sample were water content (79,21%), ash (1,09%), protein (17,21%), and fat (2,17%)
Congenital Coagulation Factor XIII Deficiency Revealed by Convulsion: A Case Report
Authors: Mebrouk N. , Benouachane T. , Chtouki L. , Jabourik F. , Bentahila A.
Published: July 2021

Factor XIII deficiency is a rare inherited disease, with a particularly high risk of intracerebral hemorrhage. We report the case of a newborn who was suspected to have a coagulation disorder at birth, due to an intracerebral hemorrhage. A quantitative dosage of factor XIII was requested but the usual coagulation tests (thromboplastin, thrombokinase, fibrinogen) were normal.  Because of unavailability of specific treatment with factor XIII concentrate, the patient was treated with fresh frozen plasma.  The initial dose was for normalizing factor XIII; subsequent monthly doses were designed for preventing the occurrence of serious bleeding.
Influence of Sulphur Fertilization on Yield, Nutrient Content and Uptake by Sugarcane in Sulphur Deficient soil of Thiruppuvanam Block of Sivagangai District
Authors: Raghunath R. , Pandian P. Saravana , Mahendran P. P. , Ragavan T. , Geetha R.
Published: July 2021

Effect of various levels of sulphur (50,100 and 150 kg ha-1) with three sources of sulphur fertilizers was studied on sugarcane crop in a field experiment conducted in Typic ustropept at Thiruppuvanam block of Sivagangai district during 2018-2019. The results revealed that the application of sulphur @ 100 kg ha-1 as FeSO4 as soil application along with application of N, P2O5 and K2O on Soil Test Crop Response (STCR) basis registered the maximum nutrient content of N, P, K & S in cane, leaf and total nutrient uptake. The cane yield (162 t ha-1) was maximum at the application of sulphur @ 100 kg ha-1 as FeSO4 followed by the treatment receiving 150 kg ha-1 of sulphur as FeSO4 inconjoint with N, P2O5 and K2O on STCR basis (157.00 t ha-1).
Impact of Magnetic Field on the Dynamic Performance of Photovoltaic-Thermal Panel with Nanofluids
Authors: Sami S.
Published: July 2021

The performance of a hybrid solar collector photovoltaic-thermal solar panel system under a magnetic field using nanofluids was presented hereby. A two-dimensional dynamic heat transfer and fluid flow model was developed to describe the behavior of the photovoltaic cell-thermal panel at different conditions such as solar irradiance, nanoparticles, different magnetic field gauss forces. different material properties, and boundary conditions. The model has been established after the dynamic mass and energy equations coupled with the heat transfer relationships, and thermodynamic properties as well as material properties under different magnetic gauss forces. Comparisons were made against literature data for validation purposes of the predictive model. The model fairly predicted the key parameters under different nanofluids conditions, magnetic fields, and compared well with existing data on the subject.