bluuebunny/crossref_metadata_2025 huggingface dataset:
Uji Aktivitas Antibakteri Kombinasi Minyak Kelapa Murni dan Arang Aktif terhadap Streptococcus mutans
Authors: Chusna Nurul , Priyadi Muhammad
Published: July 2022

Streptococcus mutans merupakan bakteri penyebab masalah pada karies gigi. Penggunaan bahan alami dipercaya menjadi salah satu terapi infeksi yang dapat digunakan sebagai antibakteri. Beberapa penelitian menunjukkan adanya potensi bahan alami seperti minyak kelapa murni dan mineral arang aktif dapat mengobati karies gigi. Hal ini mendorong untuk mengetahui aktivitas antibakteri kombinasi antara minyak kelapa murni dan arang aktif terhadap S. mutans. Pengujian antibakteri dilakukan dengan metode difusi cakram dengan mengukur diameter zona hambat. Kelompok sampel uji terdiri dari kombinasi minyak kelapa murni : arang aktif (konsentrasi 10% v/v : 5% b/v, 5% v/v : 5% b/v, dan 5% v/v : 10% b/v) dan amoksisilin 30 µg sebagai kontrol positif. Hasil menunjukkan kombinasi minyak kelapa murni : arang aktif (10% v/v : 5%b/v, 5% v/v : 5% b/v, dan 5% v/v : 10% b/v) dan amoksisillin memiliki besaran zona hambat berturut-turut sebesar  8,50 mm; 6,90 mm; 6,90 mm dan 30,04 mm. Hasil uji penelitian yang dilakukan menunjukkan bahwa kombinasi antara minyak kelapa murni dan arang aktif memiliki aktivitas antibakteri yang lemah terhadap bakteri S. mutans. Selanjutnya, perlu dilakukan penelitian lanjutan aktivitas minyak kelapa murni maupun bahan-bahan alami lainnya pada penanganan infeksi gigi dan mulut. Kata Kunci: Antibakteri, Minyak Kelapa Murni, Arang Aktif, Karies Gigi, Streptococcus mutans   Streptococcus mutans is bacteria that causes problems in dental caries. The use of natural ingredients is believed to be one of the infection therapies that can be used as antibacteria. Several studies have shown the potential of natural ingredients such as virgin coconut oil and activated charcoal minerals to treat dental caries. It is encouraging to know the antibacterial activity of the combination of virgin coconut oil and activated charcoal against S. mutans. Antibacterial testing was carried out by disc diffusion method to know the diameter of the inhibition zone. The test sample group consisted of a combination of virgin coconut oil: activated charcoal (10% v/v : 5% w/v, 5% v/v : 5% w/v, and 5% v/v : 10% w/v ) and amoxicillin as a positive control. The results showed that the combination of virgin coconut oil: activated charcoal (10% v/v : 5% w/v, 5% v/v : 5% w/v, and 5% v/v : 10% w/v) and amoxicillin 30 µg had the size of the inhibition zone was 8.50 mm, 6.90mm, 6.90 mm and 30.04 mm, respectively. The results of the research conducted showed that the combination of virgin coconut oil and activated charcoal had weak antibacterial activity against S. mutans. Furthermore, it is necessary to conduct further research on the activity of virgin coconut oil and other natural ingredients in the treatment of dental and oral infections.
PERSEBARAN URBAN HEAT ISLAND DI KOTA BANJARBARU MENGGUNAKAN PENGINDERAAN JAUH
Authors: Rahmadanti Ria , Jauhari Ahmad , Asyari Mufidah
Published: July 2022

The phenomenon of global warming occurs due to the effect of greenhouse gases. Heat waves that penetrate the earth’s layer are difficult to reflect back. The goal of this research is mapping urban heat distribution. Research related to urban heat island (UHI) can be analysed through remote sensing by lowering land surface temperature data with vegetation index to produce UHI distribution data. This research was conducted in the city of Banjarbaru using qualitative descriptive analysis and spatial descriptive. The UHI map processing result in classes 8 – 10 obtained a temperature range between 31,2 oC – 37,2 oC and humidity 53% - 65,80%. The area of this class is 2.258,30 throughout the downtown and the particularly the western of Banjarbaru. Temperature in classes 6 – 8 between 31,2 oC – 35,8 oC, humidity 56,8% - 73,2%. The area of this class is 2.258,30 hectares around Banjarbaru. Temperature in classes 4 – 6 between 29,6 oC – 34,6 oC, humidity 55,8% - 83,40%. The area of this class is 14.820,8 hectares in southwest of Banjarbaru. Temperature in class 2 – 4 between 30 oC – 34,4 oC, humidity 58,4% - 76,8%. The area is 8.570 hectares near south of Banjarbaru. Class 0 – 2 range temperature 30 oC – 34 oC, humidity 66% - 74%. The area is 1.231,4 hectares this location near east of BanjarbaruFenomena pemanasan global terjadi karena efek gas rumah kaca. Gelombang panas yang menembus lapisan bumi sulit untuk dipantulkan kembali. Penelitian ini bertujuan untuk memetakan distribusi pulau panas. Penelitian terkait pulau panas perkotaan dapat dianalisis melalui penginderaan jauh dengan menurunkan data suhu permukaan lahan dengan indeks vegetasi untuk menghasilkan data sebaran UHI. Penelitian ini dilaksanakan di Kota Banjarbaru dengan menggunakan analisis deskriptif kualitatif dan deskriptif spasial. Hasil dari pengolahan peta UHI pada kelas 8 – 10 dengan suhu 31,2 oC – 37,2 oC, kelembaban 53% - 65,80%. Luas wilayah UHI 2.258,30 ha terletak di sepanjang pusat kota dan bagian barat dari Kota Banjarbaru.Suhu pada kelas 6 – 8 antara 31,2 oC – 35,8 oC, kelembaban 56,8% - 73,2%. Luas wilayah 2.258,30 ha terletak sebagian di pusat Kota Banjarbaru. Kelas 4 – 6 dengan suhu 29,6 oC – 34,6 oC, kelembaban 55,8% - 83,40%, seluas 14.820,8 ha pada barat daya kota. Kelas 2 – 4 dengan suhu 30 oC – 34,4 oC, kelembaban 58,4% - 76,8%. seluas 8.570,3 ha terletak di tepi kota. Kelas 0 – 2 didapat suhu sekitar 30 oC – 34 oC, kelembaban 66% - 74%. seluas 1.231,4 ha pada bagian timur kota.
KARAKTERISTIK OBJEK WISATA ALAM DI WILAYAH KERJA KESATUAN PENGELOLAAN HUTAN TABALONG PROVINSI KALIMANTAN SELATAN
Authors: Evayanti Siti Fatimah , Kissinger Kissinger , Syam'ani Syam'ani
Published: July 2022

The Tabalong Forest Management Unit (KPH) has a very diverse potential for natural tourism objects, but development is still limited. ODTWA development requires more detailed data and information about the characteristics of ODTWA, so that all forms of management of the tourism object will be more precise and specific. The purpose of this study was to analyze the potential feasibility of natural tourism objects, analyze the characteristics of ODTWA natural attractions in KPH Tabalong Resort Forest Management (RPH) Kinarum. There are three natural attractions in the working area of KPH Tabalong RPH Kinarum, namely, 1) Riam Mambanin in Marindi Village, Haruai District, Tabalong Regency; 2) Riam Kinarum in Kinarum Village, Upau District, Tabalong Regency; 3) Riam Maga in Mangkupum Village, Muara Uya District, Tabalong Regency. Data was collected through field observations and semi-structured interviews. Data analysis was carried out descriptively based on the data collected. The most varied ODTWA areas and have great potential to be developed in a short time are Riam Kinarum and Riam MambaninKesatuan Pengelolaan Hutan (KPH) Tabalong memiliki potensi objek wisata alam yang sangat beragam namun pengembangan masih terbatas. Pengambangan Objek dan Daya Tarik Wisata Alam (ADOTWA) memerlukan data dan informasi yang lebih rinci tentang karakteristik ODTWA, sehingga segala bentuk pengelolaan terhadap objek wisata tersebut akan lebih tepat dan spesifik. Tujuan penelitian ini untuk menganalisis karakteristik objek wisata alam ODTWA yang ada di KPH Tabalong Resort Pengelolaan Hutan (RPH) Kinarum. Objek wisata alam yang ada di wilayah kerja KPH Tabalong RPH Kinarum ada tiga yaitu, 1) Riam Mambanin yang ada di Desa Marindi Kecamatan Haruai Kabupaten Tabalong; 2) Riam Kinarum yang ada di Desa Kinarum Kecamatan Upau Kabupaten Tabalong; 3) Riam Maga yang ada di Desa Mangkupum Kecamatan Muara Uya Kabupaten Tabalong. Pengumpulan data dilakukan melalui observasi lapangan dan wawancara semi terstruktur. Analisis data dilakukan secara deskriptif berdasarkan data yang dikumpul. Kawasan ODTWA yang paling variatif dan memiliki potensi besar untuk dikembangkan dalam waktu cepat adalah Riam Kinarum dan Riam Mambanin
ANALISIS KANDUNGAN KIMIA KAYU JELUTUNG (Dyera costulata) BERDASARKAN POSISI KETINGGIAN BATANG
Authors: Pasaribu Dahlia Nuraini , Istikowati Wiwin Tyas , Sutiya Budi
Published: July 2022

This study aims to determine the color of a sample qualitatively on jelutung wood including the base, middle, tip, and bark. Changes in color using a photometer are not only found in every type of wood, but also affect the position of the height on the stem. Color changes are generally influenced by extractive composition, temperature, humidity, light, and storage conditions (Sahin 2011). The color of the wood needs to be considered for pulp and paper, because the brighter the color of the wood, the better the quality of the pulp and paper produced. Jelutung wood has a smooth texture, the direction of the fibers is straight, and the slippery surface is slightly glossy so it is suitable for writing paper. And it can also be used as pulp and paper with the addition of chemicals and advanced treatment. Color change usually occurs due to the presence of substances that react before and after treatment on a sample.Penelitian ini bertujuan untuk mengetahui warna suatu sampel secara kualitatif  pada kayu jelutung meliputi pangkal, tengah, ujung, dan kulit. Perubahan warna menggunakan fotometer  pengukurannya tidak juga  terdapat pada suatu jenis kayu yang berbeda, tetapi juga berpengaruh pada letak ketinggian pada batang. warna yang berubah pada umumnya dipengaruhi oleh sifat komposisi dari kadar ekstraktif, suhunya, kelembabannya, cahaya matahari, dan kondisi dimana sampel kita simpan (Sahin 2011). Kayu yang berwarna perlu diperhatikan pada pulp dan kertas, sebab warna kayu yang semakin cerah akan menentukan kualitas pulp dan kertas yang bagus pula. Kayu jelutung memiliki tekstur halus, arah seratnya lurus dan permukaan licin sedikit mengkilap sehingga cocok diperuntukkan sebagai kertas tulis. Dan juga bisa diperuntukkan menjadi kertas dan pulp dengan menambahkan bahan bahan kimia juga dilakukan perlakuan lebih lanjut. Colour Change atau perubahan warna biasa terdeteksi sebab terdapatnya kandungan yang bereaksi antara zat sesudah dan sebelum perlakuan pada sampel.
PREDIKSI NILAI KARBON YANG HILANG AKIBAT KEBAKARAN HUTAN DAN LAHAN DI KOTA BANJARBARU
Authors: Dini Niken Larasati Kusuma , Jauhari Ahmad , Rachmawati Normela
Published: July 2022

Forests can maintain climate stability in the long term, vegetation in the forest can convert carbon dioxide (CO2) into Oxygen (O2). Forest and land fires produce plant vegetation and the addition of gas CO2 in the atmosphere, this can inhibit the carbon cycle in the atmosphere so that it can cause climate change. The purpose of this research is to estimate the area of forest and land fires in Banjarbaru City and carbon emissions from the burned area in Banjarbaru City. Determination of the location based on the distribution of hotspots in Banjarbaru City in 2018. In estimating the area of fire and land using the Normalized Burn Ratio (NBR) method. From the area affected by the fire, the estimated burnt carbon emissions were calculated using the Greenhouse Gas Inventory Implementation Method Vol 3, then the results obtained showed that the burned area using the NBR method had an accuracy value of 47.06%. The burned area resulting from this method was 0.43 Ha of old secondary forest, 3.51 Ha of medium secondary forest, 52 Ha of old plantation and young secondary forest and 240.95 Ha of shrubs. From the burned area, the CO2 emission values for each land cover were 11.27 tons/ha in old secondary forest, 28.28 tons/ha in medium secondary forest, 241.97 tons/ha in young secondary forest and 952.39 tonnes/ha on scrubHutan dapat menjaga kestabilan iklim dalam waktu jangka panjang, vegetasi yang berada pada hutan dapat merubah karbondioksida (CO2) menjadi O2. Kebakaran hutan dan lahan mengakibatkan hilangnya vegetasi tumbuhan serta penambahan gas CO2 di atmosfer, hal ini dapat menghambat siklus karbon pada atmosfer sehingga dapat menyebabkan perubahan iklim. Tujuan dari penelitian untuk mengestimasi luas area kebakaran hutan dan lahan di Kota Banjarbaru dan emisi karbon dari luas area yang terbakar di Kota Banjarbaru. Penentuan lokasi penelitian berdasarkan sebaran hotspot Kota Banjarbaru Tahun 2018. Dalam mengestimasi luas area kebakaran hutan dan lahan menggunakan metode Normalized Burn Ratio (NBR). Dari luas daerah yang mengalami kebakaran kemudian dihitung estimasi emisi karbon terbakar menggunakan metode Pedoman Penyelenggaraan Inventarisasi Gas Rumah Kaca Vol 3. Hasil yang diperoleh menunjukan bahwa luas area terbakar memiliki nilai akurasi 47,06 %.  Luas areal terbakar pada hutan sekunder tua 0,43 Ha, hutan sekunder sedang 3,51 Ha, perkebunan tua dan hutan sekunder muda 52 Ha dan semak belukar 240,95 Ha. Dari luas area yang terbakar di peroleh nilai Emisi CO2 pada masing-masing tutupan lahan sebesar 11,27 ton/ ha pada Hutan sekunder tua, 28,28 ton/ha pada hutan sekunder sedang, 241,97 ton/ha pada hutan sekunder muda dan 952,39 ton/ha pada semak belukar
POTENSI DAN PROSPEK PENGEMBANGAN TANAMAN SIMPUR(Dillenia indica L) DI KHDTK KINTAP KECAMANTAN KINTAP KALIMANTAN SELATAN
Authors: Siahaan Ester Nien R , Hatta Gusti Muhammad , Rudy Gusti Seransyah
Published: July 2022

The purpose of this study was to determine the potential and prospects of Simpur plant development in KHDTK Kintap. The method used is data collection used to calculate the frequency and density, the frequency with the growth area of the species in each plot is calculated to find the Important Value Index. Based on the results of the study, the dominant plant species with the highest INP at the seedling level were birik with an INP of 61.40% and the sapling level, namely Mawai with an INP of 36.11%, the dominant plant at the pole level was simpur with an INP of 51.58% and at the tree level. namely simpur with INP 23.09%. The type of simpur determined at the pole and tree level allows it to be used as a seed-producing broodstock to start cultivation and use other parts other than wood. Simpur plants can be a beneficial source of NTFPs for communities around the forest, especially KHDTK Kintap and South Kalimantan. Simpur is very promising to be developed as a prospect in developing the local potential of the regionTujuan dari penelitian ini Mengetahui Potensi dan Prospek Pengembangan Tanaman Simpur di KHDTK Kintap. Metode yang digunakan adalah pengumpulan data digunakan untuk menghitung frekuensi dan kerapatan, frekuensi dengan daerah pertumbuhan spesies disetiap plot dihitung untuk menemukan Indeks Nilai Penting. Berdasarkan hasil penelitian jenis tumbuhan yang dominan dengan INP tertinggi pada tingkat semai yaitu birik dengan INP 61,40% dan tingkat pancang yaitu Mawai dengan INP 36,11% tumbuhan yang dominan pada tingkat tiang yaitu simpur dengan INP 51,58% dan pada tingkat pohon yaitu simpur dengan INP 23,09%. Jenis simpur yang ditentukan pada tingkat tiang dan pohon memungkinkan untuk dijadikan sebagai indukan penghasil biji untuk memulai budidaya serta pemanfaatan bagian lainnya selain kayu. Tumbuhan simpur dapat menjadi sumber HHBK yang menguntungkan bagi masyarakat sekitar hutan khususnya KHDTK Kintap dan Kalimantan Selatan.Simpursangat menjanjikan untuk dikembangkan sebagai prospek dalam mengembangkan potensi lokal daerah
MODEL ARSITEKTUR POHON DI ARBORETUM FAKULTAS KEHUTANAN UNIVERSITAS LAMBUNG MANGKURAT
Authors: Hamdani Muhammad Febri , Achmad Basir , Peran Setia Budi
Published: July 2022

The research on the Arboretum Tree Architecture Model aims to analyze the types, functions and forms of architectural models that grow in the Arboretum of the Faculty of Forestry, Lambung Mangkurat University. The method used in this study was a descriptive analysis method of the architectural model. Based on the results of the analysis at the Arboretum of the Faculty of Forestry found 6 models of tree architecture from tree species with a diameter of 20 cm. The architectural forms/models of trees in the Arboretum were Aubreville with the type of ketapang (Terminalia catappa), Corner with the type of Palm Raja (Rostonea regia), Prevost with the type of Pulai (Alstonia scholaris), Raux with the type of Glodokan Tiang (Polyalthia longifolia), Troll with the type of Acacia mangium (Accacia mangium), and Cape (Mimusops elengi). It is suggested that the Arboretum of the Faculty of Forestry needs to add local tree species, especially those in Kalimantan while at the same time adding local tree architecture types so as to increase the knowledge of students or any parties who need it.Penelitian tentang Model Arsitektur Pohon Arboretum bertujuan untuk menganalisis jenis-jenis, fungsi dan bentuk model arsitektur yang tumbuh di Arboretum Fakultas Kehutanan Universitas Lambung Mangkurat. Metode yang digunakan dalam penelitian ini adalah metode analisis deskriptif terhadap model arsitektur. Berdasarkan hasil analisis di Arboretum Fakultas Kehutanan ditemukan 6 model arsitektur pohon dari beberapa jenis pohon yang berdiamater ≥ 20 cm. Pohon di Arboretum memiliki Bentuk/model arsitektur yaitu Aubreville dengan jenis ketapang (Terminalia catappa), Corner dengan jenis Palem Raja (Rostonea regia), Prevost dengan jenis Pulai (Alstonia scholaris), Raux dengan jenis Glodokan Tiang (Polyalthia longifolia), Troll dengan jenis Akasia Mangium (Accacia mangium), dan Tanjung (Mimusops elengi). Disarankan bahwa di Arboretum Fakultas Kehutanan perlu adanya penambahan jenis-jenis pohon lokal, khususnya yang ada di Kalimantan sekaligus menambah type arsitektur pohon local sehingga lebih menambah ilmu pengetahuan para mahasiswa atau pihak mana saja yang memerlukannya
RESPON PERTUMBUHAN TANAMAN KAYU KUKU (Pericopsis mooniana) DENGAN MENGGUNAKAN PUPUK NPK
Authors: Hernanda Andini Dyah , Pujawati Eny Dwi , Fitriani Adistina
Published: July 2022

The purpose of this study was to determine the percentage of nail wood seedlings and to determine the effect of the concentration of NPK fertilizer on the growth of nail wood seedlings. Parameters used include plant height, plant diameter, plant health. Based on the results of the study, the percentage of survival for nail wood grew medium success, namely 70% with 28 live seedlings from 40 seedlings, the highest percentage of survival was found in the NPK fertilizer dose of 7gr (80%) and the smallest was found in the control (60%). The increase in nail wood height with the highest value was in the treatment (2.5gr) with an average value of 3.9cm and the lowest value was found in the control. The diameter of the nail wood has the highest value at 5gr with an average value of 0.9cm increase. The increase in the number of leaves was not significantly different between the controls, 2.5gr, 5gr, and 7.5gr because the average leaf growth was 3 strandsAdapun maksud percobaan ini ialah demi memahami keuntungan semai kayu kuku serta mengetahui kontrol konsentrasi Pupuk NPK terhadap pertumbuhan semai kayu kuku. Parameter yang  digunakan diantaranya, tinggi tanaman, diameter tanaman, kesehatan tanaman. Berdasarkan hasil penelitian Persentase hidup kayu kuku tumbuh keberhasilan sedang yaitu 70% dengan 28 bibit yang hidup dari 40 bibit, persentase hidup tertinggi terdapat pada dosis pupuk NPK 7gr (80%) dan yang terkecil terdapat pada Kontrol (60%). Pertambahan tinggi kayu kuku dengan nilai tertinggi yaitu pada perlakuan (2,5gr) dengan nilai rata-rata 3.9cm dan nilai terendah terdapat pada kontrol. Diameter kayu kuku nilai tertinggi pada 5gr dengan nilai rata-rata pertambahan 0.9cm. Pertambahan jumlah daun tidak berbeda nyata antara kontrol, 2,5gr, 5gr, 7,5gr karena pertumbuhan daunnya rata-rata 3 helai.
РЕСТРУКТУРИЗАЦІЯ ПРОМИСЛОВОСТІ: ВІД НАУКОВО-ВИРОБНИЧИХ ОБ'ЄДНАНЬ ДО МАЛОГО ТА СЕРЕДНЬОГО БІЗНЕСУ?
Authors: Герасимчук В. Г.
Published: July 2022

У статті узагальнено теоретико-методологічні та практичні аспекти реструктуризації промисловості як необхідної умови стійкого розвитку та інклюзивного зростання економіки країни. Проаналізовано прорахунки ірраціонального підходу українських «реформаторів» до застосування рекомендацій «Вашингтонського консенсусу», прискореного процесу роздержавлення та приватизації власності, що призвело до деіндустріалізації економіки, банкрутства тисяч науково-виробничих об'єднань (корпорацій). Визначено основні причини низької ефективності виконання загальнодержавних та галузевих цільових економічних програм розвитку промисловості. Вказується на необхідність ефективної взаємодії в структурі промисловості великого, середнього, малого та мікропідприємництва. Здійснено оцінку рівня інноваційного розвитку національної економіки з використанням критеріїв Індексу інноваційності Bloomberg 2021. Досліджено динаміку наукоємності ВВП України у 1997-2020 рр. за видами робіт. Наголошено на необхідності прийняття невідкладних заходів з боку держави щодо підтримки розвитку фундаментальної і прикладної науки, підвищення мотивації праці науковців у створенні інноваційної, конкурентоспроможної продукції. Здійснено аналіз експортного потенціалу, який засвідчує подальший відхід країни з категорії індустріально розвинених до категорії аграрно-індустріальних, до сировинного придатку світової економічної системи. Запропоновано заходи з вдосконалення організаційного механізму управління державною промисловою політикою з посиленням ролі законодавчої та виконавчої гілок влади, системи державно-приватного партнерства в її формуванні та реалізації.
Recurrent cervical and vaginal hemorrhage in a patient with advanced cervical cancer
Authors:   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Shabunin A.V. , Podzolkova N.M. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Alimov V.A. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Grekov D.N. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Bedin V.V. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Lebedev S.S. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Sokolov N.Yu. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Batyukova T.V. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Korennaya V.V. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation, Kuranov I.I. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Sazhina A.V. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Danilov A.M. ,   S.P.Botkin City Clinical Hospital, Moscow, Russian Federation, Afanasova P.N. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
Published: July 2022

Clinical observation of recurrent cervical and vaginal hemorrhage from a tumor in a 55-year-old patient with locally advanced cervical cancer is presented. The use of uterine artery embolization was ineffective. Subsequently, the following surgical interventions were performed: laparoscopy, clipping of internal iliac arteries on both sides, coagulation of gonadal arteries. Symptomatic radiation therapy to the pelvic region with hemostatic purpose based on vital indications was performed. Positive dynamics against the background of radiation therapy was noted: complete hemostasis was achieved. Conclusion. Symptomatic radiation therapy to the pelvic region can be applied with hemostatic purpose for vital indications in case of insufficient effectiveness of traditional methods to stop cervical and vaginal hemorrhage in patients with advanced cervical cancer. Key words: radiation therapy, cervical cancer, surgical treatment, cervical and vaginal hemorrhage, uterine artery embolization
Gestational hypertension complicated by prolonged labor and labor-related eclampsia in a pregnant woman living in high-altitude areas
Authors:   Bashkir State Medical University, Ufa, Russian Federation, Tadzhiboeva N.A. , Yashchuk A.G. ,   Bashkir State Medical University, Ufa, Russian Federation, Fatkullina I.B. ,   Bashkir State Medical University, Ufa, Russian Federation, Galeeva S.A. ,   Bashkir State Medical University, Ufa, Russian Federation
Published: July 2022

A clinical case of gestational hypertension complicated by prolonged labor and labor-related eclampsia in a pregnant woman living in high-altitude areas is presented. A detailed analysis of the management of this pregnancy from patient registration at the maternity clinic to labor was performed. Methods of early diagnosis and timely and accurate assessment of the severity of this condition in high-altitude areas were provided. Key words: pregnancy, high altitude, hypertensive disorders, high-altitude hypoxia, eclampsia
Thromboelastography in obstetric practice
Authors:   Omsk State Medical University, Omsk, Russian Federation, Barinov S.V. , Medyannikova I.V. ,   Omsk State Medical University, Omsk, Russian Federation, Tirskaya Yu.I. ,   Omsk State Medical University, Omsk, Russian Federation, Beznoshchenko G.B. ,   Omsk State Medical University, Omsk, Russian Federation, Kadtsyna T.V. ,   Omsk State Medical University, Omsk, Russian Federation, Lazareva O.V. ,   Omsk State Medical University, Omsk, Russian Federation, Chulovsky Yu.I. ,   Omsk State Medical University, Omsk, Russian Federation, Prodanchuk E.G. ,   Omsk State Medical University, Omsk, Russian Federation, Tsygankova O.Yu. ,   Omsk State Medical University, Omsk, Russian Federation, Galyanskaya E.G. ,   Omsk State Medical University, Omsk, Russian Federation
Published: July 2022

The study of changes in the hemostatic system in women with a complicated pregnancy is one of the promising tasks aimed at the prevention of thrombotic complications in obstetric practice. Objective. To develop treatment and prevention strategies for thrombotic complications in women staying in maternity units based on the study of hemostatic parameters using thromboelastography (TEG). Patients and methods. The pattern of coagulation disorders in the hemostatic system was examined in 343 pregnant women with obstetric complications (pre-eclampsia, placental abruption, fetal growth restriction, and preterm labor). In 220 women, hemostatic disorders were not corrected; in 123 women, the treatment strategy was determined by the results of laboratory and instrumental monitoring of the hemostatic system. Results. The area under the ROC curve (AUC) for maximum clot firmness (MA) [AUC = 0.9 (CI = 0.83–0.95), p < 0.001] was greater than for any of the blood coagulation parameters considered. The optimal classification threshold for the MA parameter is a cut-off point of 64.4. This threshold is characterized by sensitivity of 80.3% and specificity of 81.8%. Significant thresholds for thrombotic conditions are MA > 75 mm [AUC = 0.83 (95% CI 0.76–0.90)] and R < 2 min [AUC = 0.72 (95% CI 0.63–0.81)]. Conclusion. The introduction of treatment and prevention strategies based on thromboelastography in women staying in maternity units helps to avoid such complications as lower extremity thrombophlebitis, pelvic vein thrombosis, pulmonary embolism, and cerebral ischemia. Key words: pregnancy complications, prevention, thrombosis, thromboelastography
THE ROLE OF OXIDATIVE STRESS IN THE PATHOPHYSIOLOGY OF CARDIOVASCULAR PATHOLOGY
Authors:   Krasnoyarsk State Medical University, DEMKO IRINA V. , SOBKO ELENA A. ,   Krasnoyarsk State Medical University, SOLOVYEVA IRINA A. ,   Krasnoyarsk State Medical University, KRAPOSHINA ANGELINA YU. ,   Krasnoyarsk State Medical University, GORDEEVA NATALYA V. ,   Krasnoyarsk State Medical University, ANIKIN DMITRY A. ,   Krasnoyarsk State Medical University
Published: July 2022

Introduction. In the pathogenesis of a number of diseases, a significant role is played by redox imbalance, which is referred to as oxidative (oxidative stress) stress. Aim. The aim of the study is to review current information on the pathophysiological mechanisms of the influence of oxidative stress on the development of cardiovascular pathology. Material and methods. A review of current published studies on the effect of oxidative stress on the development and course of cardiovascular pathology was carried out. Results and discussion. Oxidative stress, disorders of the antioxidant system, and inflammation are considered the leading links in the pathogenesis and progression factors of atherosclerotic cardiovascular diseases, heart failure, arterial hypertension, and others. Conclusion. By maintaining the physicochemical parameters of biological membranes regulating intracellular homeostasis and protein kinase activity, free radicals take part in key biological reactions, such as differentiation, proliferation, and apoptosis. Strengthening reactions of free radical oxidation of lipids leads to damage to membranes and enzymatic systems, acting as a trigger factor for hidden genetically determined changes. Inflammation is a pathological process inextricably linked with oxidative stress, which develops in tissues in response to their damage due to the action of agents of an infectious and non-infectious nature. Maladaptive inflammation leads to systolic and diastolic dysfunction through cardiovascular remodeling. Oxidative stress due to damage to the endothelial lining leads to the formation of endothelial dysfunction. The combination of the described pathological processes leads to cardiovascular diseases.
EFFECT OF TRANSPLANTATION OF HUMAN UMBILICAL CORD BLOOD MONONUCLEAR CELLS OVEREXPRESSING GLIAL NEUROTROPHIC FACTOR ON THE STATE OF MICROGLIA AND ASTROCYTES IN TRANSGENIC MICE WITH ALZHEIMER'S DISEASE MODEL
Authors:   Kazan State Medical University,, PETUKHOVA ELENA O. , MUKHAMEDSHINA YANA O. ,   Kazan State Medical University, TIMOFEEVA ANNA V. ,   Kazan (Volga Region) Federal University, RIZVANOV ALBERT A. ,   Kazan (Volga Region) Federal University, MUKHAMEDYAROV MARAT A. ,   Kazan State Medical University
Published: July 2022

Introduction. Alzheimer's disease is a neurodegenerative disease characterized by a progressive decline in cognitive functions. Alzheimer’s disease is the most common form of dementia and one of the main causes of disability in older people. Neuroinflammation is an important factor in the pathogenesis of Alzheimer's disease. The neuroinflammatory reaction observed in Alzheimer's disease is primarily caused by resident immune cells of the central nervous system, including microglia and astrocytes. Aim. The aim of this work was to study the effect of transplantation of human umbilical cord blood mononuclear cells (UCBMC) overexpressing glial neurotrophic factor (GDNF) on the state of microglia and astrocytes in APP/PS1 transgenic mice with Alzheimer's disease model. Material and methods. Xenotransplantation of gene-cell structures to experimental animals was carried out retroorbitally, once in the amount of 2 million cells. Immunofluorescence examination of cryostatic sections of the brain was carried out by applying antibodies to ionized calcium-binding adaptive molecule 1 (Iba1, marker of microglia and macrophages) and antibodies to glial fibrillar acid protein (GFAP, marker of astrocytes) and subsequent imaging on a confocal scanning microscope LSM 510-Meta (Carl Zeiss). Results and discussion. It was found that transplantation of UCBMC overexpressing GDNF reduced the severity of microgliosis in the parietal cortex and dentate gyrus of the hippocampus, and also reduced the severity of astrogliosis in the CA3 zone of the hippocampus of the brain of APP/PS1 mice. Transplantation of UCBMC overexpressing enhanced green fluorescent protein (EGFP) only reduced the severity of microgliosis in the parietal cortex of APP/PS1 mice. Conclusion. The data obtained indicate a high therapeutic potential of transplantation of UCBMC overexpressing GDNF in Alzheimer's neuropathology.
THE MAIN TRENDS OF TOBACCO SMOKING AMONG RUSSIAN TEENAGERS FOR 20 YEARS OF THE XXI CENTURY
Authors:   Federal Research Institute for Health Organization and Informatics, SKVORTSOVA ELENA S. , LUSHKINA NINA P. ,   Federal Research Institute for Health Organization and Informatics
Published: July 2022

Introduction. To this day, the problem of tobacco smoking among the population remains relevant throughout the world. Since the majority of smokers (about 90%) acquire this habit before the age of 18, WHO believes that special attention should be paid to protecting the younger generation from smoking and the harmful effects of tobacco. For this, it is necessary to conduct research to study the behavior of school-age children. Aim. The aim is to identify the main trends of tobacco smoking among urban teenagers-schoolchildren in the Russian Federation for the period from 1999-2000, 2010-2011 and 2019-2020. Material and methods. A sample of adolescents in each subject of the Russian Federation was formed by multi-stage selection with alternating typological, random and continuous examination. In 1999-2000, 12912 urban teenagers were interviewed, of which 5939 boys and 6973 girls, in 2010-2011 - 15323, of which 6961 boys and 8362 girls, in 2019-2020 - 14084 teenagers, of which 6535 boys and 7549 girls. Statistical development of materials was carried out using the computer program "Risk factors". The Pearson criterion 2 was used to calculate the statistical significance of the differences in indicators. Results and discussion. During the period under review, the prevalence of smoking and daily smoking tended to decrease, both among boys (4.5 times) and among girls (3.2 times). At the same time, if the prevalence of boys who smoked over girls also decreased and by 2019-2020 the proportion of boys and girls who smoked was equal, then among teenagers who smoked daily, the proportion of boys remained, as before, higher than the proportion of girls (1,2 times). The proportion of teenagers who smoked for reasons of emerging addiction ("like", "out of habit", "I can't quit") tended to increase, both among boys and girls. During the period under review, the motive of the first smoking test "curiosity", both boys and girls, retained its primacy. The age interval for introducing urban teenagers- schoolchildren to tobacco smoking has not changed either (from 10 years to 17 years inclusive). However, the "peak" of initiation to smoking in boys moved from the age range up to 10 years inclusive in 1999-2000 and, starting from 2010-2011. and in 2019-2020, for the age range of 13-14 years, for girls, the age range of 13-14 years retained its position as the "peak" of initiation to smoking. Conclusion. A comparative analysis showed a significant decrease in the prevalence of smoking among urban teenage schoolchildren in the Russian Federation.
SPECIAL ASPECTS OF GIANT RENAL ANGIOMYOLIPOMA DIAGNOSIS AND TREATMENT (CLINICAL CASE)
Authors:   Izhevsk State Medical Academy, STYAZHKINA SVETLANA N. , KHUZINA LILIYA F. ,   Izhevsk State Medical Academy, MULLAKHMETOV BULAT A. ,   Izhevsk State Medical Academy, KIRYANOV NIKOLAY A. ,   Izhevsk State Medical Academy, KUKLIN DMITRY N. ,   Izhevsk State Medical Academy, EROKHIN OLEG A. ,   First Republic Clinical Hospital, Izhevsk
Published: July 2022

Introduction. One of the rare complex diseases in clinical practice is Bourneville-Pringle disease (tuberous sclerosis). It is a genetically determined polysystemic disease with an autosomal dominant type of inheritance, one of the manifestations of which are renal angiomyolipomas. Angiomyolipoma is a benign kidney tumor. It consists of epithelioid, smooth muscle cells and adipose tissue and has abundant abnormal vascularization. Aim. We analyze a complex clinical case in a patient with a giant angiomyolipoma of a single kidney. Material and methods. Patient S., 58 years old, was urgently admitted to the urology department. The patient complained of pain in the left lumbar region, in the left half of the abdomen, blood impurities in the urine. General clinical, laboratory and instrumental research tools were conducted. Results and discussion. According to the spiral CT of the kidneys with contrasting, in the left kidney a giant mass with a violation of its architectonics, with signs of hemorrhage and a formed hematoma in the upper third of the mass and hemorrhagic impregnation of its lower half was found. Surgical treatment was prescribed, during which embolization of the segmental arteries of the left kidney, selective angiography of the left renal artery, total nephrectomy on the left with a successful outcome were performed. Conclusion. On the basis of the given clinical case, it should be concluded that despite the benign nature of the renal angiomyolipoma, the tumor has reached gigantic sizes due to the late treatment of the patient caused by concomitant oligophrenia. In this regard, the late diagnosis has led to life-threatening complications that required immediate decision-making. The given clinical observation shows the success of the chosen surgical tactics in the form of a radical operation that allowed saving the life of the patient with a rare disease. The patient was discharged from the hospital for outpatient follow-up by an urologist and a nephrologist. Regular hemodialysis, monitoring with the help of laboratory and instrumental research tools are prescribed. The patient was put on the waiting list for renal trans- plantation in specialized centers in Russia.
FEATURES OF THE TOPOGRAPHIC-ANATOMIC STRUCTURE OF THE PERHOLOUS-LOWER MANDAL SPACE AFFECTING THE EFFICIENCY OF NERVEBLOCKADES AND OTHER SURGICAL INTERVENTIONS
Authors:   National Pirogov Memorial Medical University, Vinnytsia, KUSHTA ANNA O. , SHUVALOV SERGII M. ,   National Pirogov Memorial Medical University, Vinnytsia
Published: July 2022

Introduction. The region of the pterygo-mandibular space is an anatomical formation that is quite often sub- jected to surgical interventions (blockade of the mandibular nerve and its branches, operations for purulent processes, injuries). Among the complications of these surgical interventions, there are contractures of the lower jaw, neuritis of the lower alveolar and lingual nerves, and failure of anesthesia during blockades of these nerves. The purpose of the study was to analyze literature data and anatomical preparations of the pterygo-mandibular space, to take into account different options for the location of nerves and blood vessels during blockades and operations. Material and methods. The analysis of the literature and our own anatomical studies of 8 preparations of the deep parts of the human head was carried out. Results and discussion. The pterygo-mandibular space has a rather complex topographic and anatomical structure. Its anatomical structures are mobile along with the lower jaw and, accordingly, are adapted to these conditions in the form of a tortuous course of nerves and blood vessels, which prevents their stretching, tension, and injury. These features must be taken into account when performing surgical interventions, blockades of sensory and motor nerves in this area. Spatial perception of the location of the anatomical structures of the pterygo-mandibular space is facilitated by describing them relative to the lateral and medial muscles. Conclusions: The topographic and anatomical structure of the pterygo-mandibular space is variable and complex, which must be taken into account when performing nerve blocks, diagnostics, operations for purulent processes and traumatic injuries. The pterygo-mandibular space, connected directly with the peripharyngeal, should also be considered as part of the oral pharynx communicating with the base of the skull and neck.
PARENTS’ ASSESSMENT OF MEDICAL CARE FOR THEIR CHILDREN WITH BRONCHIAL ASTHMA AND COMORBID PATHOLOGY
Authors:   LLC “International Academy of Faceplasty and Osteopathy”, ULISHCHENKO ILIYA  A. , SHULAEV ALEXEY V. ,   Kazan State Medical University, KONOVALOV OLEG  E. ,   Medical Institute of the Peoples’ Friendship University, Moscow, PAK VITALIY I. ,   Medical Institute of the Peoples’ Friendship University, Moscow, YAKHYAEVA SABIYAT  A. ,   Medical Institute of the Peoples’ Friendship University, Moscow
Published: July 2022

Currently, there is a steady increase in the number of children suffering from two or more diseases simultaneously occurring. In this regard, the assessment by parents of the medical care received by children with concomitant diseases is highly relevant. Aim. The aim of the study is to study the satisfaction of parents with medical care provided to patients with bronchial asthma and children with comorbid pathology. Material and methods. On the basis of the regional children’s clinical hospital, a selective sociological study was carried out, in which 368 parents of children aged 7 to 14 years old, patients with bronchial asthma with concomitant pathology, took part. Study design: single-center, non-randomized, uncontrolled study. Results and discussion. In the opinion of only 36.4% of the parents surveyed, inpatient medical care provided to their children is always available. The availability of outpatient care was positively assessed by only 29.5% of the respondents. In this case, the main reasons for dissatisfaction were called insufficient provision of the specified specialists and a long wait for the day of admission. The majority (81.8%) of the respondents would like to receive consultations from specialists of other profiles, taking into account concomitant diseases, when the child is in the pulmonary department of the hospital. At the same time, according to almost every second parent, the level of consultation of various specialists is higher in hospitals than in children’s polyclinics. Among the respondents, 69.3% considered themselves sufficiently informed on the issues of bronchial asthma in children. However, the results of the survey showed that only 69% of parents always follow medical recommendations. Conclusion. The presence of concomitant pathology in childhood, including with such a fairly common chronic disease such as bronchial asthma, requires special medical and organizational approaches to treatment. At the same time, it is necessary to take into account the opinion of the legal representatives of children on the availability and quality of medical care provided.
DEVELOPMENT AND IMPLEMENTATION OF THE COMBINED GEARBOX AND ITS APPLICATION ON CARS
Authors: Ostroverkh Oleksandr
Published: July 2022

A combined transmission of a car is designed, consisting of a mechanical part that will be used in all modes of movement of the car, and a variator (stepless), which is planned to be used only in traffic jams or at low speeds. A study of the use of mechanical gearboxes in traffic jams was also conducted. The input of the study determined: the total time spent in traffic, the distance traveled, the average speed of the car and how many times the driver switched the gear lever. The principle of operation of the designed transmission is described.
A study on the temperature heating of the friction disk of the main clutch of the variator part of the designed gearbox. The study was conducted using SolidWorks in the software module COSMOSWorks Designer. As a result of the study, it follows that the thermal performance of the friction disc of the main clutch when applied to a third of the higher power compared to the nominal value allows without the risk of overheating and damage to use the designed transmission
MODERN INFORMATION AND COMMUNICATION TECHNOLOGIES IN THE PROCESS OF PROVIDING QUALITY DISTANCE LEARNING
Authors: Hladchenko Oksana , Ratushnyak Tetiana , Bespartochna Olena
Published: July 2022

In the context of the global pandemic and the process of digitalization of society, the education sector has faced new problems, including the mediocre level of skills of participants in the process needed to use the distance learning technologies, insufficient digital literacy and ICT skills, unstructured educational material on educational platforms and lack of quality feedback. Therefore, the formation of new approaches to the organization of distance learning, the introduction of modern information and communication technologies for distance education and successful adaptation to them are currently the indicators of the quality of educational services. As part of the modernization of education, Ukrainian society and government are gradually mastering technologies aimed at intensifying the educational process, improving the forms and methods of training and suitability for use in distance learning. The article highlights the problem of choosing a management system of the educational process; lists the modern and latest educational platforms and additional or alternative digital tools to ensure the educational process in distance learning; discusses their functionality, advantages and disadvantages. The article considers the most popular distance learning technologies according to surveys of the State Education Quality Service of Ukraine: Viber messenger, Zoom video conferencing platform, social network Facebook, specialized learning management systems Microsoft Teams, GoogleClassroom, Moodle. There is also a brief overview of lesser-known learning management systems such as HUMAN platforms, New Knowledge and Unified School. The article notes the positive role in the development of non-formal education of such educational platforms as Prometheus, ED-ERA, iLEARN, LearningApps. It is demonstrated that the Ukrainian education sector has a sufficient number of information and communication technologies to ensure the quality of distance learning and adaptation to the new conditions of the era of digital transformation of society.
PECULIARITIES OF SOCIAL NETWORKS INFLUENCE ON STUDENTS
Authors: Stelmakh Oksana
Published: July 2022

The urgency of the issue of virtual social networks is highlighted, which is increasingly integrated into the processes and space of human socialization. The article deals with the theoretical and empirical analysis of the social networks impact on students. Peculiarities of students’ communication in the modern Internet space are analyzed. Signs of Internet addiction of young people are highlighted. The reasons for choosing an interactive way of communication are substantiated. It was found that the majority of respondents are active users of social networks. It was found that the majority of respondents are active users of social networks, have emotional difficulties in everyday communication and students have an average level of loneliness.
LEADERSHIP IN PROJECT MANAGEMENT
Authors: Ponomaryov Olexandr , Chebotarev Mykola , Kharchenko Alla , Grinchenko Marina
Published: July 2022

The necessity of developed leadership qualities of managers and all specialists in project management as an important prerequisite for the effective use of this technology is substantiated. It is shown that the theory and practice of project management have developed a range of effective approaches to the organization of the project team and the successful implementation of complex and responsible sets of work. These complexes, usually aimed at obtaining fundamentally new and often unique results, are in their systemic integrity a project. The main requirements for it are a clear time frame for its implementation, compliance with a pre-agreed budget and quality indicators. Ensuring these requirements is largely determined by the professionalism, managerial competence and personal traits and qualities of the leader.
Penetration of a plane electromagnetic wave into a moving ferromagnetic medium
Authors: Baida Evgen , Panteliat Mykhailo
Published: July 2022

The article is devoted to mathematical modeling of the penetration of the electromagnetic field into a moving ferromagnetic conducting medium. It is shown that the depth of penetration of a plane electromagnetic field depends both on the speed of movement and on the direction of movement of the medium. The movement of the medium "towards" the field reduces the depth of its penetration into the material, which is equivalent to an increase in the frequency of the field. At certain speeds of movement of the medium in the direction of the field, the penetration depth increases so much that the medium becomes "transparent" and there is no attenuation of the field. It is shown that the vibration of a thin ferromagnetic plate in the electromagnetic field, even in the case of a linear medium, leads to nonlinear oscillations of the field in the substance. The nonlinearity of the medium affects the value of the field attenuation but the nature of the field does not change significantly. It is shown that the vibration of a thin ferromagnetic plate increases the field penetration depth compared to the case of a stationary medium.