bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of Enzyme-Assisted Extraction for Food Analysis and Release of Natural Products
Authors: García Aparicio María del Prado , Marina María Luisa
Published: August 2023

The transition to a circular bioeconomic model that incorporates sustainable
extraction processes such as enzyme-assisted extraction (EAE) is motivated by climate
change, population growth, and changing diets to address food security and safety, and
preserve natural resources (land, and water) and biodiversity. EAE can be applied to
extract nutrients and bioactive molecules for food analysis and profiling, and for
industrial exploitation of bioactive compounds from novel feedstocks. Commercial
extraction processes require high recovery of the targeted compounds and must
guarantee the preservation of the biological activity of the products, which is difficult
to achieve using conventional methods. EAE is a possible alternative to preserve the
quality of final products while reducing the industrial footprint in the food sector at a
larger scale. This chapter describes the parameters that impact the extraction yield
obtained in the EAE process and provides recent examples of its successful application
for the extraction of polymers and bioactive compounds of very diverse matrices (plant,
animal, mushrooms, yeast, food waste, and insects), with emphasis on process
conditions. This chapter also identifies the challenges and opportunities of EAE and the
emerging areas of research to facilitate the economic feasibility of the enzymatic
extraction of bioactive molecules. Costs related to enzyme production and its use are
one of the main impediments to the industrial application of the EAE process. Recent
research progress suggests that reduction of EAE costs can be achieved by a holistic
approach considering all steps: enzyme production (by using cheap enzyme production
media, in-house enzyme production), selection of feedstock (i.e., food byproducts),
enzyme recycling (enzyme immobilization, nano-biocatalysts), the search of novel
enzymes (marine degrading polysaccharides), more robust enzymes (i.e.,
extremozymes) and/or enzyme improvement (bioengineering), and EAE process
optimization (minimum optimal enzyme dosage). EAE technology for food analysis
and production of bioactive molecules keeps building momentum as it is sustainable,
environmentally friendly, and innovative
Study of Machine Learning for Recommendation Systems
Authors: Deshpande Tushar , Chavan Khushi , Mangrulkar Ramchandra
Published: August 2023

This study provides an overview of recommendation systems and machine
learning and their types. It briefly outlines the types of machine learning, such as
supervised, unsupervised, semi-supervised learning and reinforcement. It explores how
to implement recommendation systems using three types of filtering techniques:
collaborative filtering, content-based filtering, and hybrid filtering. The machine
learning techniques explained are clustering, co-clustering, and matrix factorization
methods, such as Single value decomposition (SVD) and Non-negative matrix
factorization (NMF). It also discusses K-nearest neighbors (KNN), K-means clustering,
Naive Bayes and Random Forest algorithms. The evaluation of these algorithms is
performed on the basis of three metric parameters: F1 measurement, Root mean
squared error (RMSE) and Mean absolute error (MAE). For the experimentation, this
study uses the BookCrossing dataset and compares analysis based on metric
parameters. Finally, it also graphically depicts the metric parameters and shows the
best and the worst techniques to incorporate into the recommendation system. This
study will assist researchers in understanding the summary of machine learning in
recommendation systems.
Transformasi Teritori berdasarkan Kegiatan Pengunjung di Lapangan Gasibu
Authors:   Universitas Mataram, Bachtiar Jasmine Chanifah U
Published: August 2023

Personal space (proxemics) in public spaces should be considered essential to keeping the personal area separate from others. Meanwhile, privatization in public space will divide the area into small personal spaces due to the unclear form of territory in personal spaces. This study will identify and reveal the pattern of visitors’ territory transformation based on visitors’ activities in Lapangan Gasibu, Bandung. The data will be collected through observation and a survey on a weekday (Thursday) and weekend (Saturday). Then, the data will be analyzed using a descriptive analysis method based on mapping activities in the area. The result shows three transformations of spaces based on visitors’ activities and territories in Lapangan Gasibu. The pattern of transformation shows some areas of territorial spaces with unclear protection but need to avoid personal conflicts and some shared areas with low protection of territories. Thus, the thoughtful design of public spaces and physical facilities should be taken into consideration. This result is expected to be taken as a design reference for designing and creating comfortable public spaces that meet the need for personal spaces and activities.
Karakteristik Spasial - Fungsional Ruang Terbuka Hijau Taman Olahraga-Rekreasi dan Taman Bermain Anak Pada Taman Trunojoyo Kota Malang
Authors:   Departemen Arsitektur, Fakultas Teknik, Universitas Brawijaya, Adhitama Muhammad Satya , Wulandari Lisa Dwi ,   Departemen Arsitektur, Fakultas Teknik, Universitas Brawijaya, Asikin Damayanti ,   Departemen Arsitektur, Fakultas Teknik, Universitas Brawijaya, Pamungkas Sigmawan Tri ,   Departemen Arsitektur, Fakultas Teknik, Universitas Brawijaya
Published: August 2023

The existence of public space is an indication of good urban spatial planning. Activities in green open spaces are a simple way to improve mental and physical health. In post-pandemic conditions, people's preference for choosing public spaces, especially green open spaces as places for activities, socializing, or cheap recreation in the city center, has decreased. Therefore, a study was conducted to see the quality and characteristics of green open spaces which are the preferences of the people of Malang City in carrying out activities in these spaces. The research focuses on two types of green open spaces, namely sports recreation parks and children's playgrounds located in Trunojoyo Park, Malang City. This research uses a rationalistic study approach, with primary data from observations and interviews and secondary data through an assessment of 10 success criteria for public spaces according to Carmona (2019), namely evolving, diverse, free, delineated, engaging, meaningful, social, balanced, comfortable, robust. The study result shows that people's preferences in choosing green open spaces are the completeness and condition of the facilities in them.
Interdisciplinary Explorations of Neuroscience: An Active-Learning Course Companion
Authors: May Christopher J.
Published: August 2023

This text is accessible to anyone interested in the brain. It is specifically targeted to students and instructors of undergraduate neuroscience or biopsychology courses. It encourages an active exploration of the intersection of neuroscience with other disciplines through a large number of activities, demonstrations, reflection prompts, and critical thinking questions. The book complements material presented in more conventional neuroscience or biopsychology textbooks, portions of which are linked to throughout this text.
An Ecofeminist Approach to Alice Walker’s the Color Purple
Authors: Payra Biswajit
Published: August 2023

Alice walker, an iconic African-American, is one of the influential feminist writers in literature. She, in her works, has delineated how the African-American women have faced oppressions in terms of race, class and ethnicity and has lambasted both sexist and racist hegemony in addition to promoting an ecocentric worldview by dint of womanism. Her The Color Purple (1982) depicts how women as well nature are subjected to continuous exploitation and draws interconnectedness between women and nature. The paper shows how both women and nature are being exploited, subjugated and oppressed by the patriarchal world and how Celie, Shug Sofia and Squeak have been able to develop their life through eco-friendly ways of life by bucking against trouble-ridden situations.
Ferritin-Nanocaged Aggregation-Induced Emission Nanoaggregates for NIR-II Fluorescence-Guided Noninvasive, Controllable Male Contraception
Authors: Yu Xinghua , Shuai Jiaxue , Meng Ge , Zhou Shumin , Wijayaraja Amali , Zhao Yixiang , Yao Lei , Yao Rui , Yang Xing , Zhang Tianfu , Wang Liying , Gu Pengyu , Zhang Pengfei , Sun Fei
Published: August 2023

Controllable contraception in male animals was demonstrated through the
utilization of gold nanorods’ photothermal effect to accomplish mild
testicular hyperthermia. However, the challenges arising from testicular
administration and the non-biodegradability of nanoparticles hinder
further clinical implementation. Therefore, a straightforward,
non-invasive, and enhanced contraception approach is required. This
study explores the utilization of human heavy chain ferritin (HFn)
nanocarriers loaded with aggregation-induced emission luminogens
(AIEgens) for noninvasive, controllable male contraception guided by
Near-Infrared-II (NIR-II) fluorescence imaging. The HFn-caged AIEgens
(HFn@BBT) are delivered via intravenous injection and activated by
near-infrared irradiation. Lower hyperthermia treatment induces partial
damage to the testes and seminiferous tubules, reducing fertility
indices by approximately 100% on the 7th day, which gradually recovers
to 80% on the 60th day. Conversely, implementation of elevated
hyperthermia therapy causes total destruction of both testes and
seminiferous tubules, leading to a complete loss of fertility on the
60th day. Additionally, the use of AIEgens in NIR-II imaging offers
improved fluorescence efficiency and penetration depth. The findings of
this study hold significant promise for the advancement of safe and
effective male contraceptive methods, addressing the need for
noninvasive and controllable approaches to reproductive health and
population control.
The reduced function allele SLCO1B1 c.521T>C is of no practical relevance for the renal graft function over the first post-transplant year in patients treated with mycophenolic acid
Authors: Škegro Sandra Nađ , Panezić Luka , Šimičević Livija , Hudolin Tvrtko , Kaštelan Željko , Božina Nada , Trkulja Vladimir
Published: August 2023

Aim. To estimate the effect of the reduced-function polymorphism SLCO1B1
c.521T>C on the renal graft function (estimated glomerular
filtration rate, eGFR) over 12 months in patients treated with
mycophenolic acid (MPA). Methods. Consecutive eligible adults (≥16 years
of age) engrafted over a 6-year period who received MPA as a part of
maintenance immunosuppression were assessed for eGFR on 9 occasions over
12 post-transplant months. The SLCO1B1 c.521C>T variant
allele carriers (treated) and wild-type subjects (controls) were
balanced on a range of demographic, medical, and genetic variables at
baseline, and the development of eGFR (slope) was estimated with further
adjustment for time-varying covariates. A subset of patients were
assessed for exposure to MPA 5-7 days after the transplantation.
Results. The adjusted eGFR slopes from day 1 to day 28 (peak), and from
day 28 to day 365 were practically identical in treated (n=86) and
control (n=168) patients (GMR=0.99, 95%CI 0.92-1.06, and GMR=0.98,
0.94-1.01, respectively). The rates of adverse renal outcomes and
possible MPA-related adverse effects were low, and similar in treated
and controls (adjusted RR=0.94, 0.49-1.84 and RR=1.08, 0.74-1.58,
respectively). The pharmacokinetic substudy did not signal that treated
and control patients differed with respect to MPA clearance, peak,
trough or total exposure, overall (treated n=23, control n=45), if
cotreated with cyclosporine (n=17 vs. n=26) or with tacrolimus (n=8 vs.
n=17). Discussion. In patients treated with MPA, variant allele SLCO1B1
c.521T>C has no effect on the 12-month renal graft
function. It does not seem to affect exposure to- and safety of MPA.
Laparoscopic liver resection versus open liver resection for recurrent liver cancer: A systematic review and meta-analysis of PSM studies
Authors: Zhang Hui , Jiang Wenkai , Chen Xinlong , Li Xin , Du Yan
Published: August 2023

Background: Laparoscopic liver resection (LLR) has not been widely
accepted for recurrent liver cancer (RLC). This study aims to conduct a
systematic review of the current literature for determining LLR
effectiveness and safety for patients with RLC. Methods: Before April
2022, a comprehensive literature search was undertaken in Web of
Science, PubMed, and Embase relied on a specified search strategy for
eligible propensity score matching (PSM) studies comparing LLR or OLR.
Meta-analysis of operative times, duration of stay, mortality, blood
loss, overall survival rate, blood transfusion, recurrence-free survival
rate, and overall complications was undertaken using a
random/fixed-effects model. Results: Eight PSM studies of LLR versus OLR
were incorporated, including 1128 patients. The current meta-analysis
revealed nonsignificant variations between the two groups in overall
survival rate, operation time, blood transfusion, mortality, overall
complications, and long-term recurrence-free survival rate.
Alternatively, when LLR is compared to OLR, LLR results in lower blood
loss (p=0.002) and a shorter hospitalization (p=0.04). Conclusion:
Although both techniques appear equal, LLR seems to have certain
advantages over OLR. Notably, the evidence quality is generally confined
to cohort studies, necessitating the performance of a high-quality
randomized trial that compares both approaches. Keywords: Laparoscopic
surgery, Liver resection, Recurrent liver cancer, Propensity score
matching, Meta-analysis.
Anthropogenic and natural disturbances increase local genetic diversity in an early spring geophyte (Ficaria verna Huds.)
Authors: Guicking Daniela , Kessler Sarah , Störmer Eliza , Bersch Maggie , Duchoslav Martin
Published: August 2023

Tetraploid Ficaria verna is a common spring geophyte that forms large
populations in central Europe and is considered invasive in northern USA
and Canada. It is considered an almost seed-sterile taxon, relying on
vegetative reproduction by underground tubers and aerial bulbils. Recent
studies have revealed high levels of population genetic diversity in F.
verna, raising the question of how genetic diversity is maintained and
which factors may be responsible for the observed patterns. Polymorphic
nuclear microsatellite markers were established to define multi-locus
genotypes (MLGs), to analyze fine-scale spatial genetic structure (SGS)
using grid and cross sampling schemes, and to quantify genetic diversity
within and between nine populations with different disturbance regimes
in central Germany. 115 MLGs were identified among a total of 347
samples. The G/N ratio varied between 0.16 and 0.70 among populations,
and in each population a number of unique MLGs occurred. Genotypes were
highly intermingled within populations, suggesting a ‘guerrilla’
dispersal strategy. Significant negative SGS was found in five out of
nine populations in fine-scale cross sampling (up to 4 m) and in only
one population in grid sampling (up to 14.6 m). No single MLG was found
in more than one population, while many alleles were shared between
populations. Within-population genetic diversity increased with greater
exposure to both anthropogenic and natural disturbances. Regular gap
openings, facilitated propagule establishment (vegetative and sexual),
and propagule dispersal by water and mowing machines are likely
important factors explaining the positive effects of disturbance on
local genetic diversity of F. verna.
Water Mass Transformations Within Antarctic Coastal Polynyas of Prydz Bay from Clustered Drifters
Authors: Murakami Margaret , Nummelin Aleksi , Galton-Fenzi Benjamin Keith , Uotila Petteri
Published: August 2023

Antarctic Bottom Water (AABW) forms the deepest limb of the meridional
overturning circulation (MOC) and is a key control on global exchanges
of heat, freshwater, and carbon. Density differences that drive the MOC
have their origin, in part, in coastal polynyas. Prydz Bay polynyas in
East Antarctica are a key source of Dense Shelf Water (DSW) that feeds
AABW to the Atlantic and Indian Oceans. However, several poorly
understood mechanisms influence the pathways and change water mass
properties of the DSW on its way to the abyss. To better understand
these mechanisms, we release Lagrangian particles in a 10 km resolution
simulation of the Whole Antarctic Ocean Model and analyze the resulting
tracks using novel cluster analysis. Our results highlight the role of
mixing with other water masses on the shelf in controlling the fate of
DSW and its eventual contribution to AABW. When advected beneath the ice
shelf, DSW can mix with fresh Ice Shelf Water (ISW), becoming less dense
and making future AABW formation less likely. This study confirms that
towards the shelf break along the Antarctic Slope Current, mixing with
circumpolar deep water (CDW) forms modified circumpolar deep water
(mCDW) and influences DSW export as AABW. Our findings indicate that the
pathway from DSW to AABW is sensitive to mixing with ambient waters on
the shelf. An important implication is that with future increase in ice
shelf melt and CDW warming, AABW production is likely to decline, even
if DSW production in coastal polynyas remains constant.
Commentary on: “Chronic Use of Hydrochlorothiazide and Risk of Skin Cancer in Caucasian Adults: A PharmLines Initiative Inception Cohort Study
Authors: Bright Heber Rew , Chandy Sujith  J. , George Renu
Published: August 2023

Abstract is missing (Correspondence)
Caracterización físico - química de accesiones de maracuyá (Passiflora edulis var. Flavicarpa) en el Centro de Formación Agroindustrial.
Authors: Murcia Torrejeno Valentín , Machado Cuellar Leidy , Saavedra Mora David , Artunduaga Cuellar Yudy Paola , Flórez Rojas Marco Fidel
Published: August 2023

El Maracuyá es un fruto con alto potencial agroindustrial en el mercado de productos, en este sentido el objetivo de este estudio fue caracterizar físico y químicamente accesiones de maracuyá (Passiflora edulis var. Flavicarpa) en el Centro de Formación Agroindustrial, se seleccionaron cuatro accesiones redonda, ovalada, pequeña y grande, se evaluaron un total de doce variables físicas (Diámetro del fruto, Longitud del fruto, Peso del fruto, Firmeza del fruto, Diámetro del pericarpio del fruto, Peso de la pulpa más semilla, Porcentaje de la pulpa más semilla, Peso del jugo, Porcentaje del jugo, Peso de la cáscara, Peso de la semilla, Índice de semilla, cuatro químicas (Sólidos solubles, Ácido cítrico, pH, Actividad acuosa) y el rendimiento del jugo. El análisis de los resultados se realizó mediante un análisis de varianza con la prueba de Tukey (p<0,05) y un análisis multivariado, análisis de componentes principales (PCA). Se halló alta variabilidad de los carácteres fenotípicos y agronómicos de los frutos en las accesiones grande, ovalada, pequeña y redonda, con las siguientes cifras: peso del jugo 41,13%, peso de la semilla 39,12%, índice de semilla 37,46%, diámetro del pericarpio del fruto 24,41% y peso de la pulpa más semillas 31,42%. La cantidad de °Brix presentó los mayores valores en la accesión categorizada como pequeña con 18,05, la cual mostró diferencias significativas en relación con las otras accesiones. En este sentido, estos valores permiten determinar el uso potencial de cada accesión, ya sea para la comercialización de la fruta fresca o aprovechamiento agroindustrial.
Recuperación de suelos degradados por sobrepastoreo, con diferentes sustratos en el departamento de Putumayo, Colombia
Authors: Santander Quiñones Bayron Esteban , Chaves Fernández Lisnarda Paola , Rodríguez Pantoja Oneyda Nathalia , Rosas Torres Gina Lorieth , Ordóñez Ortega Tatiana , Riascos Vallejos Adrián Rolando
Published: August 2023

El mal manejo de praderas inicia con la pérdida del vigor de las plantas, trae propagación de malezas y propicia la compactación del suelo; así, deteriora gravemente las propiedades físicas y químicas del mismo. Ese proceso es intensificado por la ganadería extensiva. Con el objetivo de evaluar la recuperación de suelos degradados por sobrepastoreo con diferentes sustratos –compost bovino, compost porcino y abono verde–en el departamento de Putumayo, se utilizó un diseño estadístico irrestricto al azar y se aplicó el test de Tukey para las diferencias entre medias. Los resultados arrojan que aritméticamente los tratamientos T4 (precompostaje bovino) y T2 (abono verde) son mejores. Sin embargo, el CV = 53,75 y (p<= 0,05) indican que no hubo diferencias entre tratamientos; esto puede deberse a factores como especie forrajera, fertilidad del suelo, prácticas de manejo del cultivo y el clima durante el proceso. Por consiguiente, los precompostajes no tuvieron reacción por las razones anteriormente expuestas y se concluye que tanto la aplicación de compostajes como la implementación de forrajes pueden ser efectivas para mejorar las cualidades de los suelos. En todo caso, hay que tener en cuenta variables como las condiciones climáticas (altas temperaturas); estas tienen efecto negativo en los procesos de germinación de la especie forrajera.
Evaluation the Safety and Quality of Ready-to-Eat Sandwiches: Short Communication
Authors: Bulushi Ismail M Al
Published: August 2023

Increase in the consumption of ready-to-eat foods such as sandwiches, raises concerns about its microbial safety and quality. The aim of the study was to evaluate the microbial safety and quality of different type of sandwiches. In total 60 of chicken shawarma (15), normal chicken (15), eggs (15) and meat (15) sandwiches were purchased from different cafes and evaluated microbiologically for total bacterial and Enterobacteriaceae counts and incidence of Salmonella sp. The results showed that the total bacterial counts were 5.48±1.01, 5.53±1.11, 5.58±0.97 and 6.72±0.77 log10 CFU g−1 in the chicken shawarma, normal chicken, eggs and meat sandwiches respectively, whereas, the counts of Enterobacteriaceae in chicken shawarma, normal chicken, eggs and meat sandwiches were 3.56±1.02, 1.63±1.30, 2.48±1.76 and 3.64±1.81 log10 CFU g−1 respectively. Salmonella sp. was suspected in 10% of the sandwiches. In conclusion, all most sandwich types were found at satisfactory level except meat sandwiches which were found at marginal level. Microbial contamination and hygiene handling status indicated that almost all sandwich types were at marginal level except normal chicken sandwiches which were found at satisfactory level. Strictly implementation of food safety laws and further studies were recommended to clarify the safety and quality of the sandwiches.
“Efficiency of the Buikstra & Ubelaker and Ferembach Methods, In the Estimation of Sex in Human Skulls from the Department of Ayacucho, Peru”
Authors: Juscamaita Leslie Arriaran
Published: August 2023

The estimation of sex in human skulls has been a very controversial issue over the years, due to the interpopulation sexual dimorphism that exists. For this reason, we have decided to carry out the following work, in which we will apply and discuss two qualitative methodologies in a sample of 84 adult skulls (male and female), from the Forensic Investigations Laboratory of the Department of Ayacucho - Peru in order to study the effectiveness of these methodologies. Each methodology will have numerical indicators that will represent the degree of sexual dysmorphism, in certain areas that vary differently according to the methodology. In the Buikstra & Ubelaker method we will assign degrees in 5 zones inside the skull; while in the Ferembach method we will evaluate 17 areas between the skull and the jaw that will be detailed later. When obtaining the results of both methodologies, it was observed that there is a significant difference between both methods, being the qualitative method Buikstra & Ubelaker with more successes, thus concluding its greater effectiveness in estimating sex in human skulls.
New Perspectives on Isoglaridacris multivitellaria Amin, 1986 from the Lake Chubsucker Erimyzon sucetta (Lacépède) in Silver Lake, Wisconsin
Authors: Amin Omar M
Published: August 2023

Specimens of Isoglaridacris multivitellaria (Caryophyllidae) were described from the posterior-most region of a lake chubsucker Erimyzon sucetta (Lacépède) in the land-locked Silver Lake, Wisconsin in November, 1978. All 4 adult specimens were found in one individual host and have never been reported again since. Specimens are distinguished from all others of the genus Isoglaridacris by their extensive post-ovarian vitellaria, and long distance between its cirrus sac and ovary. The cirrus sac is with concentric rings and the ovary is also characteristically follicular. The original description was well documented and included 9-line drawings. We describe and measure additional structures and include microscope images from all 4 specimens that clarify many of the features not readily presented with line drawings. The relic distribution of worms maybe related to the disjunct post-glacial distribution of their primary and only host, E. sucetta. We propose that I. multivitellaria may be found in the same host species elsewhere within its normal range of distribution
Granular Cell Tumor, When to Think About it? Clinical Case
Authors: Barcenas Alejandra Arellano
Published: August 2023

We present the case of a female patient with a lesion on the dorsal of the tongue, of two years of evolution, whose histopathological diagnosis was granular cell tumor. We are recapitulating the epidemiological, clinical, histological, treatment and prognosis characteristics, for a better understanding of the pathology
Physical Training for Pregnant Women: The Theoretical Knowledge and what is Recommended in Gyms
Authors: Serra Fernando Tadeu
Published: August 2023

Background: Physically active pregnant women have better anatomical and physiological conditions to gestate and give birth when compared to sedentary pregnant women. However, poorly planned physical training during pregnancy can become a problem for maternal-fetal health. Objective: From this point of view, this research was designed to analyze the knowledge of Physical Education professionals about the prescription and supervision of physical training for pregnant women. Methods: A self-administered questionnaire was answered by 16 Physical Education professionals from different gyms in the city of Mogi das Cruzes, São Paulo, Brazil. Results: We identified that most participants recommend the practice of flexibility, aerobic, and resistance exercises during pregnancy. Intensity recommendations for aerobic and resistance training for pregnant women ranged from light to moderate. The time of aerobic and resistance exercise recommended by professionals was lower than the internationally recommended (150-300 minutes/week). A significant part of the sample does not recommend resistance exercises that involve the pelvic muscles. No participant knows the six physiological variables that must be controlled in pregnant women who are exercising. Conclusion: These findings show that the participants have an important theoretical limitation on the practice of physical exercise in pregnant women and, consequently, gyms neglect training for pregnant women.
Understanding the Voluntary and Involuntary Aspects of the Sleep Mechanism
Authors: Zanou Ayao
Published: August 2023

This article deals with quantum biology, the new tool to complete traditional biology and answer difficult questions about living organisms and human existence. We elucidate the involuntary aspect of the sleep mechanism with the work of Nobel laureate Prigogine on dissipative structures and introduce the concept of spontaneous symmetry breaking; we explain why sleep and syncope are two protective mechanisms to prevent it from occurring in living organisms.
Pediatric Chronic Diseases and Health Related Quality of Life
Authors: Zaky Eman Ahmed
Published: August 2023

Health Related Quality of Life (HRQoL) is classically defined as the functional effects of a disease and of its ensuing therapy on a patient as perceived by the patient himself
THE FEKETE -SZEGO ̈ PROBLEM OF ANALYTIC FUNCTIONS BASED ON THE DEFERENtIAL OPERTOR AND CERTAIN SUBCLASSES
Authors: Văn an lý
Published: August 2023

In this paper I use the operators Dmβ,η(η, φ)f, Sm(d, β, η) and Cm(d, β, η).To establish |a3−μa22 | -functional inequalities for the Fekete-Szeg ̈o problem. That’s my main result.
Effectiveness of Friction Force Reduction in Sliding Motion Depending on the Frequency of Longitudinal Tangential Vibrations, Sliding Velocity and Normal Pressure
Authors: Leus Mariusz , Gutowski Paweł , Rybkiewicz Marta
Published: August 2023

The article presents the results of experimental research and simulation analyses of the influence of slip velocity, normal pressures and vibration frequency on the effectiveness of friction force reduction carried out in sliding motion in the presence of forced tangential vibrations. In experimental studies, changes in the driving force were measured during the slip of the upper body over the vibrating lower body. The direction of these vibrations was parallel both to the contact plane and to the direction of movement of the shifted body. The simulation tests were carried out in the Matlab/Simulink environment through the use of numerical procedures that were specially created for this purpose. Dynamic friction models considering the tangential compliance of contact and the phenomenon of pre-sliding displacement were used for calculations. The paper presents the designated values of the so-called coefficient of average friction force reduction in sliding motion for the following friction pairs: steel C45–steel C45, steel C45–cast iron GGG40 and steel C45–polytetrafluoroethy-lene PTFE (Teflon). The results of numerical analyses were in good agreement with those of experimental tests. A significant dependence of the level of average friction force reduction on the frequency of forced vibrations, sliding velocity as well as the kind of sliding pair material, and normal pressures was shown.
Owls’ responses to forest conservation in the Alps
Authors: Nemček Vladimír , Kohl Barbara
Published: August 2023

As inhabitants of cavities, some owl species benefit from natural processes, different tree compositions and higher volumes of dead wood. We assumed that protected areas would have a positive impact on the owl community. We compared the abundance of calling owls on 22 lines in managed versus protected forests. Here, we recorded the acoustic communication of owls. The composition of the owl community did not differ between areas. However, we found the impact of forest landscape integrity index and altitude on the diversity of owls. Forests in protected areas probably need time to develop natural and heterogeneous habitat structures. The conservation priority should be to increase the integrity of the forests. Our results also confirmed that managed forests can have a high diversity of owls.
Identification on the Need of English Public Speaking Class for Students at the Tourism Destination Study Program
Authors: Milawaty Milawaty , Andadari Mutika , Aditya Vemas , Utami Lely Dian
Published: August 2023

This study aims to identify the need of English public speaking skill for students at the Tourism Destination Study Program and formulate the required solution. This study was motivated by recent student events called “Seminar Pariwisata” or Tourism Seminar where all the students had to present their projects from the Integrated Field Practicum and also “Duta Polije”, a contest where campus ambassadors were selected. This study was an aftermath evaluation following the conducted events with the hope to bring an improvement in the future for both the students and the study program. This was a descriptive-qualitative study and the data were collected through observation, documentation and interview. The results of the study show that there is a need in providing students with English public speaking skill through intensive public speaking classes, to support them especially in non-academic activities. This is also useful to equip them with additional competencies in order to help them in the workplace after graduation, especially to have a career in the tourism business. The class can be conducted during the running academic year by integrating the class with English courses, by adding the public speaking class at the speaking skill section of the RPS (Semester Teaching Plan) and BKPM (Student’s Workbook) of English courses. This idea is suggested to be taken into consideration to create a better educational supports for the students as well as for the development of the study program in the future.
Hacia una protección adecuada del Patrimonio Cultural o Conocimientos Tradicionales
Authors: Rosillo Pantoja Izarelly , Ibarra Cervantes Karen Vanessa
Published: August 2023

This paper presents a normative analysis on the instruments that give effectiveness to the legal norm in the matter of cultural heritage. The objective is to identify how, within the scope of Mexican Law, the protection of traditional knowledge of indigenous peoples and communities could be guaranteed, taking into account the standards proposed by International Law. Although there are legislative advances, such as the issuance of the Federal Law for the Protection of the Cultural Heritage of Indigenous and Afro-Mexican Peoples and Communities, there are still challenges to face in order to harmonize with copyright and intellectual property regulations.
O protesto como instrumento para expressar o pensamento no Brasil e na Colômbia e sua interpretação dos Tribunais Constitucionais e da Corte Interamericana de Direitos Humanos.
Authors: Leventi Guimarães Rodrigo , Da Silva Barros Cinthia , Calgaro Cleide
Published: August 2023

The present study analyzes how the protest act is based on the Legal Order in Brazil, Colombia and how their respective Constitutional Courts interpret it. It is also important to identify the legal nature of the right to protest, in particular as an instrument to express thought, opinion and claims aimed at improving state functions. Finally, the understanding of the dimension of the expression of thought by the Inter-American Court of Human Rights. The applied methodology was empirical, studying doctrinal and jurisprudential bibliographic material from both States, as well as from the decisions of the IACHR.
La ‘Modernidad’ y el ‘Capitalismo’ como categorías determinantes en la transformación de la naturaleza filosófica del ejido en México
Authors: Ramos Vera Rodrigo Octavio , Vázquez Avedillo José Fernando
Published: August 2023

This work focuses, mainly, on establishing the main figure of tenure and agrarian exploitation in Mexico, called ejido, underwent a radical transformation as a result of the last great constitutional reform in agrarian matters that occurred in the year 1992. Which had as consequence that this agrarian figure suffered a change not only legal but philosophical. By changing its purpose and its social and vindictive essence, where the categories of Modernity and Capitalism had an importance in terms of the mutation of the agrarian paradigm in the country. This was done in order to fully identify the figure of the ejido to explain its current situation and find the causes of its stagnation and decline in the panorama of agricultural production and quality of life of the ejidatarios in Mexico. Allowing to understand how from the establishment of the ejido, this was an imposed figure in the country, to later suffer its great legal and philosophical transformation, which has as a consequence the current situation that exists in the ejidos in Mexico.
FORMACIÓN DEL PROFESORADO CON PERSPECTIVA DE GÉNERO: IMAGINARIOS EXCLUSORES Y TRANSFORMADORES CONSTRUIDOS EN LA ACADEMIA POST MOVIEMTO FEMINISTA EN CHILE EL 2018
Authors: Garrido Andrea
Published: August 2023

El artículo se presenta como parte de la visibilización a nivel internacional de las desigualdades de género que se han perpetuado en los distintos espacios institucionalizados, siendo uno de ellos la educación superior y otro la escuela. El movimiento feminista del 2018 en Chile, permitió acentuar esta discusión y aunque se reconoce desde la academia la problemática, existe escasa evidencia que muestre la realidad de las instituciones desde un enfoque metodológico mixto. El estudio muestra el diagnóstico de la perspectiva de género a nivel de planes formativos en una facultad de educación de una universidad en Chile. A partir de la revisión de programas de estudio y discursos de la academia se evidenció ausencia a nivel prescriptivo de criterios asociados a la formación con perspectiva de género, mientras que a nivel declarativo se reconoce la necesidad de abordar la temática como parte de la formación del profesorado desde una mirada institucionalizada. Los principales resultados señalan que, si bien el diagnóstico de los planes formativos no es auspicioso, existe consenso para la instalación de una perspectiva de género a nivel transversal. La investigación, si bien aporta a la discusión de la configuración del currículum en la formación del profesorado como espacio transformador o exclusor, también abre la discusión respecto a la dimensión estratégica de la universidad para la consolidación de una política de género para la formación inicial docente.
DA NORMA E DA CULTURA, DA LITERATURA E DO GÊNERO: RESISTÊNCIAS
Authors: De Oliveira Gomes Fabiana , Seffner Fernando
Published: August 2023

O artigo trata da literatura como artefato cultural portador de pedagogias do gênero e da sexualidade, ou seja, modos de ensinamento acerca de tais temas. Valoriza a narrativa literária como repositório da diversidade, por conter em si inumeráveis singularidades em diálogo. Seleciona obras literárias de autoras brasileiras contemporâneas: Natalia Borges Polesso – contos presentes no livro ‘Amora’ – e Clara Corleone – crônicas que integram o livro ‘O homem infelizmente tem que acabar’ –, e as analisa tendo em vista a diversidade e a construção de modos de resistência à norma, conectando-as com densidade democrática. Lida com as noções de autoria de mulheres, feminismo, norma, cultura, literatura, relações de gênero, representações, diversidade, democracia, historicidade dos modos de ser, resistência, cisheteronorma, marcadores sociais da diferença. Mostra e analisa conexões entre as autoras e suas obras, isto é, marcas culturais relacionadas à autoria presentes em suas produções, inserindo tal debate tanto no campo da literatura quanto da política.
FLIGHT SAFETY OF MI-8 HELICOPTERS AND THEIR MODIFICATIONS
Authors:   State Research Institute of Tests and Certification of Armament and Military Technique, Pilipenko Oleg
Published: August 2023

The article is an overview and information. The presented statistical data on the safety of flights of Mi-8 helicopters for the period from 1996 to 2011, the number of incidents, flight hours and their distribution for 2015-2019 confirm the feasibility of switching to the operation of helicopters according to their technical condition. The risk of fatal injury changes from its maximum values at 1000-1200 hours of operation per incident and reaches its minimum values starting from 4000 hours of operation.The number of incidents associated with the main gearbox is less for the Mi-8T helicopter compared to the Mi-8MTV(AMT) helicopter. The number of operating hours per incident associated with the operation of the fire alarm system in the area of the engines and the main gearbox also testifies in favor of the Mi-8T helicopter. The probability of an incident occurring per 1 hour of flight for a Mi-8 helicopter is less than that of the aircraft presented in the corresponding chart
A Visible Light Driven Direct synthesis of Industrially Relevant Glutaric Acid Diesters from Aldehydes
Authors: Bhowmick Anindita , Chatterjee Abhijit , Pathak Sidharth S. , Bhat Dr. Ramakrishna G.
Published: August 2023

Alpha-substituted glutaric diesters are synthesized directly from acrylates and aldehydes under visible light. This process provides a direct access to alpha-substituted glutaric diesters by exploring the HAT property of Eosin Y followed by the consecutive Giese type addition. We have performed the reaction under sunlight as a sustainable alternative light source. As an application of this protocol, the biologically potent and industrially relevant substituted 4,5-dihydro-2H-pyridazinones have also been directly synthesized from alpha-substituted glutaric diesters. A detailed and systematic control experiments have been carried out to investigate the plausible mechanistic pathway.
Is there still a place for linearization in the chemistry curriculum?
Authors: McCluskey Andrew
Published: August 2023

The use of mathematical transformations to reduce non-linear functions to linear problems, which can be tackled with analytical linear regression, is commonplace in the chemistry curriculum. The linearization procedure, however, assumes an incorrect statistical model for real experimental data; leading to biased estimates of regression parameters and should therefore not be used in formal data analysis. This fact is overlooked in many chemistry degrees, students do not yet have the mathematical knowledge to appreciate why linearization leads to bias when it is introduced. I hope that this commentary will start a discussion around the place of linearization in the chemistry curriculum, and more broadly around how mathematical and statistical training is currently provided to chemistry students.
Affine deformation and self-assembly alignment in hydrogel nanocomposites
Authors: Pereira Espíndola Suellen , Norder Ben , M. B. Jansen Kaspar , Zlopasa Jure , J. Picken Stephen
Published: August 2023

Tailoring order in hierarchical structures is a key goal of bioinspired nanocomposite design. Recently, nacre-like materials have been developed by solvent evaporation methods that are scalable and attain advanced functionalities. However, understanding the alignment mechanisms of 2D-fillers, nanosheets or platelets, remains challenging. This work explores the possible pathways for nanocomposite ordering via orientation distribution functions. We demonstrate how the immobilization of 2D-materials via a (pseudo)-network formation is crucial to alignment based on evaporation. We show a modified affine deformation model that describes such evaporative methods. In this, a gel network develops enough yield stress and uniformly deforms as drying proceeds, along with the immobilized particles, causing in-plane orientation. Herein, we tested the dominance of this approach by using a thermo-reversible gel for rapid montmorillonite (MMT) particle fixation. We researched gelatin/MMT as a model system to investigate the effects of high loadings, orientational order, and aspect ratio. The nacre-like nanocomposites showed a semi-constant order parameter ( ~0.7) over increasing nanofiller content up to 64 vol.% filler. This remarkable alignment resulted in continuously improved mechanical and water vapor barrier properties over unusually high filler fractions. Some variations in stiffness and diffusion properties were observed, possibly correlated to the applied drying conditions of the hybrid hydrogels. The affine deformation strategy holds promise for developing next-generation advanced materials with tailored properties even at (very) high filler loadings. Furthermore, a gelling approach offers the advantages of simplicity and versatility in the formulation of the components, which is useful for large-scale fabrication methods.
Pengabdian Masyarakat Edukasi Ibu Hamil dan konseling Antenatal Care Terpadu di Wilayah Kecamatan Karimunjawa
Authors: Khayati Nikmatul , Dhamanik Reina , Machmudah Machmudah , Rejeki Sri , Pawestri Pawestri
Published: August 2023

Pelayanan kesehatan selama kehamilan merupakan hal penting bagi ibu hamil maupun janin yang dikandungnya. Upaya pelayanan tersebut merupakan pencegahan terhadap kondisi buruk yang dapat terjadi pada ibu hamil. Salah satu faktor yang mempengaruhi hasil kesehatan baik untuk ibu dan janin adalah dengan Antenatal Care. Menurut Dinas Kesehatan Kabupaten Jepara dalam Rencana Strategi Dinas Kesehatan 2017-2022 (Renstra Dinkes) mengidentifikasi permasalahan berdasarkan tugas dan fungsi pelayanan Dinas Kesehatan Kabupaten Jepara terkait kesehatan ibu dan anak yaitu masih belum optimalnya pelayanan kesehatan ibu hamil K4 dan masih ditemukannya ibu hamil KEK yang diakibatkan salah satunya belum semua ibu hamil mendapatkan pelayanan KIA sesuai standar. Terkait dengan beberapa alasan tersebut maka dilakukan progam pengabdian kepada masyarakat berupa edukasi dan konseling Antenatal Care Terpadu (ANC) untuk ibu hamil. Hasil pelaksanaan kegiatan pengabdian masyarakat ibu hamil antusias dan meningkat pengetahuan dengan adanya pemeriksaan ANC Terpadu dan pemberian edukasi konseling mengenai kehamilan terutama yang b eresiko. Dengan adanya kegiatan konseling ANC Terpadu meningkatkan taraf kesehatan ibu dan janin selama masa kehamilan untuk mencegah terjadinya komplikasi dalam kehamilan, semakin banyak ibu hamil yang sadar akan pentingnya pemeriksaan ANC Terpadu akan meningkatkan kepedulian ibu terhadap kehamilannya.
PROPOSED MECHANISM FOR BREAST CANCER METASTASIS: THE PIERCING AND SUCTIONING OF CANCER CELLS MATERIAL INTO THE INTERCELLULAR SPACE DURING CRYSTALLIZATION
Authors: Embi Abraham A.
Published: August 2023

The purpose of this manuscript is to introduce a hypothesis correlating the process of hydroxyapatite crystallization as a factor allowing for the transfer of intracellular breast cancer matter into the intercellular space by rupturing cellular outer membranes. In addition, this matter could also be transferred into the lymphatic system to be disseminated, thus metastasis. The hypothesis is supported by published in vitro experiments where during crystallization lipid cells are being ruptured by advancing crystals. As fluid evaporates during crystallization, a Backwards Suction (BS) phenomenon of cells and debris has been also documented to occur during crystals formation of the anisotropic Potassium Ferricyanide when within approximately 1 mm of human tissue. This BS during crystals formation is herein hypothesized to be a mechanism dislodging tissue in type II ductal fragile malignant breast cancer tissue. The cellular material would then be pierced by the crystals and suctioned by the lymphatic circulation with its consequences.
GREEN BONDS AND ASSURANCE PROCESS: FIRST PROPOSITIONS ABOUT THE ROLE OF ACCOUNTING PROVIDERS
Authors: Baldarelli Maria-Gabriella
Published: August 2023

Green bonds seem to become more and more a key pillar of Green Finance to reach sustainable and socially responsible finance. Through a periodization the paper has the objective to analyze, among different actors, how the process of auditing (assessment) is able to contribute to transparency and effectiveness of strong sustainability purposes. Many perplexities are linked to this on the actual effectiveness of these investments to ensure the improvement of the environment and climate and on the actual ethics and transparency of management of the various phases of issue and auditing / assurance of the same. These perplexities have prompted the curiosity of the wishes of the paper which aim to respond to the following research question: “How auditors participate and seek to establish the particular market segment of green bonds?”.