bluuebunny/crossref_metadata_2025 huggingface dataset:
Positive Reinforcement Techniques as a Media to Improve Social Interaction Capabilities in Adolescent with Hebefrenic Schizophrenia
Authors: Krisnawardhani Karina Kandhi , Noviekayati IGAA
Published: August 2021

This study aims to intervene in one of the adolescent patients with hebephrenic schizophrenia who are in RSJ Menur Surabaya. The Researcher gave an intervention in the form of behavioral therapy which is a positive reinforcement to be able to improve the ability of social interaction with others, dare to socialize with the environment or actively participate in groups. The intervention carried out eight meeting sessions. Each session has a different target according to indicators of social interaction. If the client is able to reach the target, the researcher gives an reward in the form of praise, food or activities (for example: drawing) that he likes.This therapy is believed to be able to increase the ability of social interaction. The method used in study is an experimental with a case study approach. Before the behavioral interventions that appear on the client are ideology of greatness, visual and auditory hallucinations, don’t want to communicate with others, like to be alone, lack confidence, and do not participate in group activities. After being given an intervention the client realizes his mind is only an imagination, no longer hears whispers, wants to communicate with others, and is active in a group. The results of this study indicate that positive reinforcement is effectively used as a medium to improve the ability af social interaction on the subject.
The Effect of Anti-Smoking Advertising on Changes in Smoking Intentions in Active Smokers
Authors: Harahap Mohammad Febrian Nurrahman
Published: August 2021

Intentions to smoking represents people motivation to smoke. Exposure to anti-smoking ads considered as one of the most effective way to overcoming people intentions to smoke. Current study aims to see the effect of anti-smoking ad on smoking intentions in active smokers. This experimental quantitative study using an anti-cigarette advertisement video as an intervention method. Subjects (N = 20 people) are an undergraduate student who also an active smoker, with aged range from 18-24 years old. The result of paired sample t-test hypothesis showed that there is significant difference of smoking intentions (p <0.05) before (M = 20,35; SD = 0,244) and after (M = 13,85; SD = 0,549) the intervention was given. An average difference of 6.5 indicates that anti-smoking ad exposure can be said to have a major impact to decrease individual smoking intentions. The modeling principles from social learning theory and teror management theory explain the changing in intentions that occured in this study. The implications of this research will be discussed further.
Mobile-based Tajwid 1 Learning Media at the Gontor Entrance Guidance Institution with the Demonstration Method
Authors: Dzaky Muhammad Sirajuddin Mumtaz , Muriyatmoko Dihin , Taufiqurrahman
Published: August 2021

Darussalam Gontor Modern Boarding School (PMDG) graduates established tutoring institutions in their respective regions. The institution is called Bimbingan Masuk Gontor (Bimago). Currently, prospective students who want to enter Gontor have difficulty learning Tajwid 1 because of the limited learning media that still use printed books and the number is limited. This requires other media, one of which is a smartphone. The purpose of this research is to facilitate prospective students who want to learn the PMDG version of Tajweed 1. This study uses a Software Development Life Cycle approach and applies a demonstration method to its content. Application testing is done in 4 ways. With the blackbox method, it shows the application is running smoothly. The use of hardware with 5 smartphones of various brands and a screen size of at least 5.20 inches indicates the application is running well. A learning media expert gave an average of 94.38%. Six Tajwid teachers gave a score of 88.40%. The results of this study can be concluded that this application can help as an effective learning tool.
Web Based Online Exam Application for Junior High School
Authors: Ramadhan David Eka , Astutik Ika Ratna Indra
Published: August 2021

Exam is one form of evaluation used to assess the delivery of lessons that have been taught by teachers to students. The test is conducted to measure the achievement of students as students. If the results of the evaluation of the student learning process are deemed not optimal, the teaching and learning process must be improved in terms of both quality and quantity. Conventional exams are currently considered less effective, because they require a large amount of money and take a relatively long time to correct test results. The purpose of this study is to facilitate students and teachers in the process of administering the exam and can increase the effectiveness of the exam. The method used in this research is the waterfall method. While the data collection technique using quantitative techniques. The result of this research is a web-based online exam application which is expected to make it easier for students to work on exam questions anywhere using available devices
Website-Based Information System for Posyandu Services (Case Study of Posyandu Kemuning 1, Prasung Village)
Authors: Firmansyah Danang , Astutik Ika Ratna Indra
Published: August 2021

The development of toddlers is very important to continue to be monitored. Monitoring the growth and development of toddlers is carried out through monthly services at the posyandu, posyandu cadres will record the results of weighing the weight, height, and immunizations that have been received by toddlers. With this system, it is hoped that it can help the implementation process of the posyandu which includes the process of recording the results of the posyandu. This research method uses the System Development Life Cycle (SDLC), which uses a quantitative, systematic, planned, and clearly structured approach from the beginning of the research design. The purpose of this information system is to make it easier for the public to obtain information about the posyandu which includes the results of the posyandu implementation without having to come to the posyandu to ask for data on the results of the posyandu every month. The result of this research is to build a Website-Based Posyandu Service Information System. The conclusion of this study, can be used as an alternative to the use of technology so that it can be used to record the results of posyandu activities and archive storage reports on toddler development quickly, precisely and accurately.
Decision Making System Internet Addiction in Children Aged 7-17 Year Use Forward Chaining Method (Case Study : Terik Village – Krian, Sidoarjo)
Authors: Ratna Elfi , Ratna Ika
Published: August 2021

Based on a survey conducted by the APJII (Indonesian Internet Service Providers Association) team in 2018 with a percentage of more than 64.8% using the internet. The highest percentage is at the age of 7-19 years, which is 91%, this shows that the number of internet users is getting higher every year. This study aims to help treat children who are addicted to the Internet and as advice or a reference for making decisions on how to deal with people who are addicted to the Internet. The method used was to collect data on the distribution of questionnaires or questions that were carried out directly on children aged 7-17 years in the blistering village. The results of external application testing with Likert scale calculations get a percentage result of 78.36% (very useful).
Optimization of Employee Workload to Achieve Effectiveness of Man Power Planning at PT. SPINDO Depo Samarinda
Authors: Budi Setya , Putra Boy Isma , Cahyana Athika Sidhi , Sari W Indah Apriliana
Published: August 2021

Intense competition in today's industrial world requires companies to keep abreast of developments. The more years, higher the need for labor costs. To reduce high production costs, one step is to cut existing labor. By cutting the number of workers, the workload that will be borne by workers will also increase. PT. SPINDO, is a manufacturing company engaged in the production of the steel pipe industry. To expand market reach, a breakthrough was made to open a new depot located in the city of Samarinda. At the beginning of the opening along with the Covid-19 outbreak, market demand was minimal. The impact on the work load in the depot is also low. The Full Time Equivalent method is a calculation process that uses working time as a reference in determining workload. In this research, the workload value most of the employees at PT. SPINDO Depo Samarinda is included in the underload category. So that man power planning is needed by cutting the number of existing employees to balance work load and the number of manpower. After the manpower planning was carried  out, the work load that was previously unbalanced was balanced because the workload had been distributed to the employees.
Cattle Disease Diagnosis Expert System in Bandes Village, Ainaro District
Authors: Amaral Barreto Marito De Oliveira , Indahsari Rina Dewi
Published: August 2021

Most of the people in the Bandes village of Ainaro district work as breeders. Cows that are raised are beef cattle. One of the obstacles that exist in Bandes Village is the existence of a few veterinarians in Bandes Village. This research discusses an expert system for diagnosing diseases in cattle, which functions to help determine the disease that is being suffered by cattle, this system will display the results of the diagnosis in the form of the name of the disease, a description of the disease solution and its prevention. In this study there were 4 diseases studied and 7 symptoms. From the 4 disease data, isolation of the problem area, target decision and dependency diagram is made. After that the formation of IF – THEN rules, after the rules are made, the backward chaining process is made. So as to produce a solution to overcome disease in cattle. In program testing is done by comparing the results of the system with experts. In the trials that have been carried out, the results obtained are appropriate or the accuracy of the data and facts obtained from experts on cattle. So based on the results of tests that have been carried out on the system as much as 4 data, the accuracy value obtained is 100% accurate which shows that the expert system is functioning properly in accordance with the expert's diagnosis
Potential Gain in Customer Value and Customer Satisfaction Index Method For Analysis of Customer Satisfaction Level (Case Study In Pt. Anteraja)
Authors: Data Sancha Arema , Jakaria Ribangun Bamban
Published: August 2021

UD PT. Tri Adi Bersama is a technology-based shipping service company known as Anteraja and sends packages by courier called Satria. This company is a supporter of Tokopedia's ecommers and will expand to other marketplaces. Currently, staging stores exist throughout Indonesia, except Papua. In the world of expedition or competing services from various companies, there are so many companies, but from all of that companies must think creatively in the services they provide to customers or consumers, companies must compete - competing for creativity in program problems that they will apply in their promotional system. Other online services have also been rampant in the general public and for competitors they also have promo programs and express facilities have tough challenges compared to other services which are only in the form of dropship services in staging areas. The Pick Up service is a service that is featured from the expedition of the Triputra group with a specified pick-up period, so the shiper or what can be called the shop owner can control and manage delivery schedules without being confused about delays in delivery The purpose of this research is to obtain complaint data to evaluate the level of customer satisfaction so that it can be used as a benchmark for companies in improving their service systems to customers using the CSI and PGCV methods.
Population Data Management Information System Of Population And Civil Registration Department
Authors: Nurul Latifah  , Arizona Firdonsyah
Published: August 2021

Population data is the main supporting component needed in data processing in the population office, population data must be recorded and managed so that it becomes a complete, structured and clearly organized database. The data that has been successfully obtained is used for monitoring the population in the environment. The Sleman Regency Population and Civil Registration Office has been using various systems based on each sector, but with this there are still some obstacles faced in the process of collecting population data in Sleman Regency. The purpose of this research is to describe the implementation of the Population Administration Information System in the Management of Identity Cards (KTP) at the Department of Population and Civil Registration in Sleman Regency. Data collection was carried out by the stages of field studies, literature studies, data collection by means of interviews to observation, data processing, then analysis and conclusions. The data were analyzed qualitatively and quantitatively. This research is also used as material for an overview of the flow of the existing system in the Office of Population and Civil Registration (DUKCAPIL) of Sleman Regency, regarding the feasibility and efficiency of database management from systems related to population data in Sleman Regency. The results of this study are in the form of a data entry flow design to an information system that can be used as a reference or guide and produce physical forms in the form of KIA, KK and KTP in the Department of Population and Civil Registration of Sleman Regency.
Expert System for Diagnosing Human Skin Diseases Using Web-Based Naïve Bayes Method
Authors: Sari Khoirunnisa devita , Eviyanti Ade
Published: August 2021

Skin disease is a disease that often found in tropical countries like Indonesia. According to the survey, skin disease is the third of the ten most outpatient diseases. Lack of public knowledge about skin diseases and how to prevent and treat them can cause a person to develop acute skin diseases. The purpose of this research is to create an expert system application for diagnosis of human skin diseases using the web-based naïve Bayes method. With expert system, it hoped that human skin diseases can be detected early and can minimize the occurrence of more dangerous diseases. The calculation in this expert system uses the naïve Bayes method. This expert system makes diagnosis by analyzing input of symptoms experienced by patient and then processing it using certain rules according the expert knowledge that has been stored in the knowledge base. The result of this research is to build an expert system for diagnosing human skin diseases using website-based naïve Bayes. The results of the system trial of 20 respondents were the website could provide diagnosis results based on the inputted rules and could diagnose skin diseases properly. This website can used as an alternative use of technology so it can be used to diagnose skin diseases quickly, precisely and accurately. So in the future the handling of skin diseases can be faster and more efficient.
Forecasting the Number of Offset Printing Machine Breakdowns Using the Support Vector Machine (SVM) Metdhod
Authors: Khumaidah Nafis , Sukmono Tedjo
Published: August 2021

PT. MJT is a company engaged in manufacturing that produces various types of plastic tubes for cosmetic packaging. Production activities at PT. MJT uses an intermittent process, which in the printing division requires a longer total setup time because this process produces various types of specifications of goods to order. This has an effect on the amount of engine breakdown. The purpose of this research is to try the method of forecasting the number of breakdowns for offset printing machines at PT. MJT. One of the methods used in this research is the Support Vector Machine method. Support Vector Machine is a method that can help predict the number of breakdowns that will be experienced by the offset printing machine at PT. MJT. Support vector machine is a method that can reduce the error value in forecasting compared to other methods. From this research, it is hoped that it can produce a forecast of the number of breakdowns for offset printing machines at PT. MJT for a period of one year or twelve periods.
Designing Web Based Offering and Sales Information System (Case Study : PT. Daya Berkah Sentosa Nusantara)
Authors: Ramadhany Siti Nurjanah , Eviyanti Ade
Published: August 2021

Technology is increasingly sophisticated with over time competition in the business world such as E-Commerce has a positive impact on entrepreneurs to advance their companies, namely by creating online websites so that offerings and sales are easy among the public. By accessing the website page of PT. Daya Berkah Sentosa Nusantara buyers do not have to come directly to the place or company, and send offers according to admin needs.The purpose of this study is to make it easier for researchers to solve supply and sales problems based on problems that arise in the company. The method used in this study is the Waterfall Method, with data collection techniques used using observation, interviews and literature study. The desired result of this research is to be able to create a website for the company, to be able to expand marketing reach, buyers can view products through the website.
Design and Build Animated Procedures for Praying in Mosques During a Pandemic
Authors: Septiawan Rian , Taurusta Cindy
Published: August 2021

The world is currently shocked by the presence of a new type of outbreak, namely the Corona virus, which has now troubled human health, an educational animation has been made so that it can convey health protocol information to be conveyed to the public in a more interesting way. This research method using observation is a data collection by observing mosque visitors who often ignore health protocols. The results of this study indicate the importance of implementing health protocols and procedures for carrying out health protocols, especially for mosque congregants who will pray.
Analysis of Product Quality and Service Quality on Customer Satisfaction at the Surya Mart Mart Business Center using the Structural Equation Modeling Method
Authors: Yannu Prasetyo  , Atikha Sidhi Cahyana
Published: August 2021

Service quality is a superior value for customers to improve business performance or company marketing represents a level of excellence to meet consumer expectations. Therefore, it is not necessary to know what factors affect product quality and service quality at the Surya Mart Business Center Surya Mart Business Center. Surya Mart Business Center Surya Mart's Business Center is located on campus 2 of the Muhammadiyah University of Sidoarjo (UMSIDA), the market is for students, lecturers, UMSIDA employees and the surrounding community. To find out the factors that affect product quality and service quality, research uses Structural Equation Modeling, which is ia statistical technique that is able to analyze the pattern of relationships between data constructs and indicators, one data construct and another, and direct measurement errors. The results showed that the highest loading factor value was 1.329 in the discount indicator, for the term indicator, namely the additional factor with a value of 0.664. Test structural modeling on the relationship between constructs that have a casual or causal relationship. The results of this study, Variable Product Quality and Service Quality, the second variable has a significant influence on the Customer Satisfaction variable.
2D Based Puppet Character Introduction Game Using Construct 2
Authors: Pertiwi Siska Dyah , Taurusta Cindy , Suryawinata Mohammad , Findawati Yulian
Published: August 2021

Indonesia has a very diverse culture. As in Java, many people still use Javanese language and have their own special art namely wayang. Many people now do not know about who the puppet characters, education has an important role to develop the potential and character of children. Fun learning media is needed by students. This research uses library study methods and interview to elementary school teachers. This game covers Javanese language subjects in grade 3-5, especially discussing material about puppet characters. Materials used under the 2013 Curriculum. This game has 3 level stages. In each game, players must collect 3 puppet after which the player will get the final score and also information about the puppets material adjusted to the level of Class. Also conducted 4 test with an average percentage of 98% and get a good response.
Web based Information system for selling spare parts and custom bicycle frames (Case Study Of The Surabaya Minion Shop)
Authors: Oktaviano Muhammad Hendra , Fitrani Arif Senja
Published: August 2021

The purpose of this research is to design and produce an Online Shop application that is a Web that can provide information on goods data related to the sale of spare parts and custom frames that they are looking for. The research method used is the waterfall method, while the techniques for data collection use observation and interview techniques. The spare part data is obtained from visiting from shop to shop and the shop itself. The result of this research is to make it easier for customers to find the spare parts they want and to make more and more bicycle enthusiasts, especially onthel mini bikes, use them.
Selection of Fish Raw Material Suppliers by Integrating ANP and Topsis Methods in CV. Riki Utama Mandiri
Authors: Fajar Iman Sakti Aula , Sulistiyowati Wiwik
Published: August 2021

CV. Riki Utama Mandiri is a company in distributing an economic fish frozen product. This company distributed any kind of retail and wholesaler, both domestic and export. They distributing many frozen fish products variant such as Patin Fillet and Shark Fin. The all raw materials of those frozen seafood was obtained by three different suppliers. The common problems found in CV. Riki Utama Mandiri mostly about raw patin fish supplier which often committed delivery delays.  The purpose of this research is to fixing the supply chain management in deciding the more accurate selections of raw materials supplier. To overcome the common problems that happen. Analytical network process (ANP) will simplify the criteria weight values and sub criteria of each supplier. Meanwhile, technique for others reference by similarity to ideal solution (TOPSIS) method is used for giving a rank order of the alternative supplier. This research is expected for being a consideration for the company in obtaining a good and more effective kind of raw supplier. We also expecting the company for tighten supplier selection more effective way so that it can fullfilled the existing standard. Also to overcome the common problems such as delivery delays, competing raw materials with uncertain quality, and difficulty in sort out the raw materials due to size issues.
Optimization Of Cutting Chicken Routes
Authors: Sunandi Ovi Miru , Sulistiyowati Wiwik
Published: August 2021

This study has the title Optimization of Chicken Cut Retrieval Route. The existence of this study aims to reduce the distance of chicken retrieval routes from cages to slaughter mills, as well as reduce the number of deaths and chicken kesetresan when descending from the chicken carrier fleet. The method in the study used saving matrix method and vehicle routing problem. The method of data collection used is to take primary data that is taken data from the location of cut parik and chicken coop taken by the fleet so far and secondary data taken dati preentase route from the slaughter plant to the chicken coop. And obtained the maximum chicken cut and decreased the death rate and chicken kesetresan with the length of saving matrix route 219.58 Km, using 5 trucks, spent fuel Rp. 141.263, and driver's salary of Rp. 26.250.000. While using vehicle routing problem route length 209.38 Km, using 5 trucks, spent fuel Rp. 134.775,  and driver's salary of Rp. 26.250.000.
Web-Based Expert System for Diagnosing Gastric Disease Using Bayes Theorem Method
Authors: Anggilina Ayu , Eviyanti Ade
Published: August 2021

Health is a very expensive thing, so it takes an awareness to protect it. The human body has many limbs, one of which is the stomach. Gastric disease is a disease that cannot be accommodated, because if left untreated it can cause other diseases to arise and can also cause death if it is not immediately supported. Gastric disease can be caused by an inappropriate diet, a burden on the mind and also an infection caused by bacteria. The author took the initiative to create a web-based gastric disease diagnosis expert system using the Bayes theorem method which is useful for gastric disease sufferers in diagnosing their own gastric disease. The method used by researchers is the Bayes theorem method. The data collection technique used is quantitative data techniques. The results that have been achieved from this research are that it can prevent and minimize the risk of gastric disease in sufferers or the community.
Prototype Social Distancing Reminder Using HC-SR04 Sensor At The Payment Counter Via A Smartphone
Authors: Perdana Ferry Wahyu , Ayuni Shazana Dhiya , Wisaksono Arief , Syahrorini Syamsudduha
Published: August 2021

Starting from the beginning of March 2019 and even until the end of 2020, the Indonesian people are experienced prolonged suffering due to the emergence of a new type of infectious disease called Corona Virus 2019. Social Distancing is a program that aims to prevent the transmission of the COVID-19 disease as early as possible. In this research, the method used is the observation technique and literature study for the implementation of the HC-SR04 sensor as one of the distance sensors used for distance reminders implemented in public spaces using IoT as a monitoring system. The results obtained are the reading accuracy of the HC-SR04 sensor is quite accurate to 100% accuracy and when the HC-SR04 sensor detects less than 8cm (1meter real distance) then the DF Player will sound, the LCD will display a display “Jaga Jarak Anda! ", And there will be a notification"Peringatan: Kondisikan Jarak" on a smartphone that has the Blynk application installed.
Monitoring of Fuel Height Gauge at IoT-Based Gas Stations
Authors: Alawi Nuril , Sulistiyowati Indah
Published: August 2021

The increasing number of motor vehicles has been increasing the fuel demands, especially the demands for ‘pertalite’ (product of fuel) and ‘pertamax’ (product of fuel) fuels. These fuels are usually placed in a cylindrical reservoir at an SPBU (gas station) that is located below the ground surface. To find out the remaining volume of BBM (fuel), gas station attendants usually check it manually by dipping the meter stick to the bottom of the reservoir. Then, the boundary surface of the fuel is used as a reference in reading the meter value. Because it was considered to be an ineffective measurement, an Android-based electronic media was created to make it easier. This tool uses the HC-SR04 ultrasonic sensor to detect the fuel height level in the reservoir. To show the results, the Blynk application is applied for the user interface. To support the IoT (internet of things) system, NodeMCU is used that is included with the WIFI module so that it can be connected to the internet. Based on the tests that have been done, the HC-SR04 ultrasound sensor has good accuracy and can monitor the height levels of fuel in real-time.
Application Development Design “How To Make Money Online” Using The Wartefall Method (Case Study : CV Satoeasa For Indonesia)
Authors: Prasandi Agil Setyo , Hardiani Tikaridha
Published: August 2021

CV Satoeasa is a organization engaged in training and consulting services in the context of empowering and developing business actors. Satoeasa is supported by personnel who have competency standards and experience in the fields of entrepreneurship and local economic development. CV Satoeasa Untuk Indonesia is committed to increasing entrepreneurial capacity and is passionate about realizing a growing and developing business. use of the application "How To Make Money Online" to increase competitiveness with other companies, improve the quality of service to customers because now customers have more options to browse applications, compare and analyze services and ratings before choosing an application to be installed on their phone device . For the development of the application "How To Make Money Online" CV Satoeasa For Indonesia plans to create a web-based application with the aim of making it easier for customers to access it without having to install their personal device first. This research uses the waterfall method. In the waterfall method there are several steps including requirements, design, implementation, verification and maintenance. This "How To Make Money Online" application is still based on Android, therefore the author intends to make a web-based "How To Make Money Online" application development design. The result of this research is an application development design. Application development is easier with the application design that will be developed. The conclusion is the "How To Make Money Online" application development design using HTML (HyperText Markup Language) programming. Before this application was developed, it was based on Android and after it was developed it became web-based. In this application there are several menus including the homepage, articles, contacts, about us and help. Provide solutions to CV Satoeasa Untuk Indonesia regarding the design of the application development "How To Make Money Online" using the waterfall method
Expert System for Diagnosing Early Symptoms of Stroke Using the Fuzzy Mamdani Method
Authors: Sylfanie Sekar Mayang  , Ade Eviyanti
Published: August 2021

One of the dangerous diseases is stroke because it can disrupt the nervous system system in humans so that sufferers of this disease often experience paralysis in their body parts. Therefore, an application is needed to assist medical personnel when doctors are not available or are not on duty. Expert system applications are needed in early diagnosing the characteristics of the disease suffered by a patient. Expert systems are computer-based systems that use knowledge, facts and reasoning techniques to solve problems. The purpose of this study is to make it easier for researchers to identify problems with stroke based on the symptoms experienced by the patient or a person. The research method used is the fuzzy mamdani method. Data collection techniques are quantitative data techniques. The results that have been achieved from this study are that it can prevent and reduce the risk of stroke that can occur as early as possible in sufferers or the community and reduce the death rate in stroke patients.
Forecasting Production Trafo to Get SDOH Using Seasonal ARIMA Method in PT. XYZ
Authors: Dwi Septian Muhammad Dio , Sukmono Tedjo
Published: August 2021

In the production process at PT. XYZ has a fluctuating data pattern and contains seasonality. This resulted in a reduction in the company's operational efficiency and difficulty in preparing supplies to meet uncertain demand. The method according to the demand pattern at PT. XYZ in this transformer product is the SARIMA method. The results of forecasting on transformer production at PT.XYZ gets the SARIMA(1,0,1)(1,1,1) model with influenced by the results observed at 13 weeks and errors at 14 weeks ago. The results of this forecast are used in determining the safety stock in 2021 with regard to SDOH. The SDOH planning in January 2021 will run out in 30 days with a stock plan of 838 units LV Busing so that a company policy needed to increase or decrease the stock plan if SDOH is below or above 30-35 days.
Web-Based Classroom Loan Information System (Case Study Student Organizations at Muhammadiyah University of Sidoarjo)
Authors: Alfian Maulana Fajar  , Ika Ratna Indra Astutik
Published: August 2021

This research was aimed to create a website based information system that can be used for summarize the flow and facilitate borrowing space in the University of Muhammadiyah Sidoarjo by student organizations. The research method used by researchers is the waterfall method, but the data collection technique uses several ways, namely observation, interviews, and also literature study. Researchers made observations in student organizations to obtain data, in addition to met with the Directorate of Asset and Environmental Management to obtain data. The result of this research is that student organizations can borrow space online, and make it easier to recap data and also minimize duplicate data in the system. With more efficient procedures, the borrowing process becomes easier and more practical
E-Commerce Marketing Strategy & Industrial Packaging Design to Increase Profit for Bontang Manggrove Syrup Products in Tanjung Laut Indah Village, Bontang City
Authors: Nurrohkayati Anis Siti , Al Syahrin M. Najeri , Kusumawati Yulia Tri , Khairul Muhammad
Published: August 2021

The business industry of the product of the fruit syrup ovata mangrove is an effort belonging to Ibu Amirah, the head of the Fragrant Leaf group (Paguyuban usaha Mangrove village in Tanjung Laut Indah, South Bontang, Bontang City, East Kalimantan province. In the implementation of the activities successfully identified and resolved several problems of the partner namely processing, the provision of business tools processing of mangrove syrup, identification of packaging design shortage, advertisement production of mangrove fruit syrup in the e-site Commerce and demonstration of how to process e commerce and social media sites. In the overall stages of activity, the team of devotion also coordinates and interviews with the forestry service of the province of East Kalimantan which became the authorized institution in the management of the mangrove fruit syrup and its cultivation in the city of Bontang. Hopefully in this stage, partners can independently add products, conduct sales control, and use e commerce sites to the fullest without relying on the team.
Deletion of Dnm1 Gene In Mitochondria Lead To The Changes of Cell Dynamics and Energy Metabolism In Fission Yeast
Authors: Tan Xiumei , Ding Xiang , Yuan Rongmei , Hou Yiling
Published: August 2021

Mitochondria are dynamic organelles that undergo cycles of fission and fusion. The major mitochondrial fission protein is dynamin-related Drp1 GTPase (Dnm1 in yeast). The effects of Dnm1 gene deletion on cell dynamics and energy metabolism during mitosis were studied in Schizosaccharomyces pombe. Dnm1 gene deletion can lead to slow growth, abnormal sporulation, abnormal number and length of interphase microtubules of Schizosaccharomyces pombe. The deletion of Dnm1 gene can also affect the spindle growth speed and growth time of metaphase and anaphase, and affect the spindle fluorescence intensity of prophase and metaphase. At the same time, the structure and dynamics of the spindle microtubules of Dnm1Δ are also different. The statistics of spindle length showed that there was delayed spindle fracture in Dnm1Δ Cells. Two different chromosome behaviors, normal and lagged, were observed by living cell imaging. The analysis of coenzymes, intermediates and energy in energy metabolism showed that there were some abnormalities after Dnm1 gene deletion, including coenzyme defects, intermediate metabolite defects and ATP production defects.
Phyto Mediated Silver Nanoparticle Synthesis Coated Fabrics Towards Antibacterial Potential
Authors: Kabeerdass Nivedhitha , Murugesan Karthikeyan , Ramasamy Srinivasan , Mathanmohun Maghimaa
Published: August 2021

Sore repairing since occurrence up to dry skin formation (scar) is a precious process gifted by nature. Immunology takes a predominant part in healing. A sore which is sustained just now, within minutes/hours is usually ignored till its uninterrupted scar formation. When is delayed that persists for many days, many weeks, more months, even for years is keenly noticed and is seeking secondary healing which is donated by medical men. Uninterrupted natural healing is usually processed by the immune system of the host when healing is delayed then comes interruption of the medical experts with the inclusive of medicines such as synthetic chemicals, phytotherapy, micro nano particles mingled medicines, botanical flora yield Phyto metal micro therapies which going for updated management like 3D bioprinting is in practice. An array of twenty exudates of nasal, pus, urine, stool, and blood are collected from the diverse age group of sex in various wards of SOTS (such as ICU, CCU, maternity, and casualty) from the Hospitals of Madurai. After isolating from other commensals its phenotypic character is studied through gram staining and biochemical tests. To get rid of their pathogenicity a cheap, cost-effective, eco-friendly potential medicinal ingredients possessed Amaranthaceae family yielded Alternanthera sessilis mediated fabrics coated silver nanoparticles were synthesized. In the case of MIC of AS-AgNPs against isolates zone of inhibition of the E. coli is 16mm > S. aureus is 15mm at 60µg. But in the case of MIC of fabrics against isolates the E. coli and K. oxytoca show susceptibility of 19 mm in mixed cotton. In a confirmation study of AS-AgNPs in FTIR, a sharp band is observed between 1500-500cm-1, in SEM with EDAX a graph was observed between 2.6–3.9 and black white crystals measured at 200nm in HR-TEM. Nanotechnology conjoined with herbal therapeutics provides a promising solution for wound management strategies.
Application Research on End-To-End Deep Person Re-Identification
Authors: Xu Qingzhen , Qiao Han , Liu Shuang , Liu Shouqiang
Published: August 2021

Pedestrian detection refers to the technology of predicting and locating the location of pedestrians in video or image. However, the recognition accuracy of existing re-identification methods needs to be improved. In this paper, the deep learning method is adopted, and the pedestrian detection based on YOLOV3-spp is combined with the pedestrian re-identification based on Resnet50, to construct the deep pedestrian re-identification system. In the training part, the COCO training set containing only pedestrian images is used to train pedestrian detection. WGAN-GP was used to expand the pedestrian re-identification training set of Market1501, and pedestrian re-recognition training was carried out on the expanded dataset to reduce the interference of pose diversity in the learning process. In the detection part, the system first uses the pedestrian detection to locate the original image and cut out the corresponding image, then input the cut image and the target image into the person re-identification network to learn the image features, and finally the classifier judges the image containing the target. In the experiment, the identification accuracy of the system is 87.5% on the Market-1501 test set, and the identification speed of each picture is 0.12s.
Stemness and NK-like signatures define a subtype of esophageal squamous cell carcinoma with poor prognosis
Authors: Jiang Guozhong , Wang Zhizhong , Cheng Zhenguo , Wang WeiWei , Zhang Zifang , Lu Shuangshuang , Xu Huisha , Dong Yunshu , Chen Peinan , Zhang Zhongxian , Gao Dongling , Wang Zhimin , Miao Jinxin , Xue Xia , Wang Pengju , Zhang Lirong , Gangeswaran Rathi , Liu Peng , Dunmal Louisa Chard , Li Junkuo , Guo Yongjun , Dong Jianzeng , Lemoine Nicholas , Li Wencai , Wang Jun , Wang Yaohe
Published: August 2021

To explore the biology of esophageal squamous cell carcinoma (ESCC) and identify new therapeutic opportunities, comprehensive genomic-transcriptomic characterizations of 120 Chinese ESCC patients were performed. Here we show that ESCC can be categorized into differentiated, metabolic, immunogenic and stemness subtypes based on transcriptomics, with each subtype exhibiting unique molecular and histopathological features. The stemness subgroup, with four key signature genes (WFDC2, SFRP1, LGR6 and VWA2), has the poorest prognosis and was associated with downregulated immune activities, a high frequency of EP300 mutation/activation, functional mutation enrichment in Wnt signalling and the highest level of intratumoural heterogeneity. The immune profiling further revealed ESCC tumour cells overexpress NK cell markers XCL1/2 and CD160 as a new immune evasion strategy. Strikingly, XCL1 expression also affects the sensitivity of ESCC cells to common chemotherapy drugs. This study opens up new avenues for ESCC treatment and provides a unique public resource to better understand and treat ESCC.
­Actual Evapotranspiration for Sugarcane Based on Bowen Ratio-Energy Balance and Soil Water Balance Models with Optimized Crop Coefficients.
Authors: Martins Suelen da Costa Faria , Santos Marcos Alex dos , Lyra Gustavo Bastos , Souza José Leonaldo , Lyra Guilherme Bastos , Teodoro Iêdo , Ferreira Fábio Freitas , Júnior Ricardo Araújo Ferreira , Almeida Alexsandro Claudio dos Santos , de Souza Renan Cantalice
Published: August 2021

Evapotranspiration is an important parameter to evaluate soil water deficit and water use efficiency, especially at places with irregularly distributed precipitation.The aim of this study was to assess the daily actual evapotranspiration (ETa) estimated by the Thornthwaite and Mather soil water balance method adapted for crops (ThM) and by the dual Kc approach with the crop coefficients optimized from inversing modeling and by the adjustment procedure suggested in FAO-56. The models comparison and optimization were performed with actual evapotranspiration determined by the Bowen ratio – energy balance method (ETβ) for sugarcane at full canopy closure grown in Alagoas State, Northeastern Brazil. The objective function of the inverse problem was defined in terms of ETβ and ETa estimated by the ThM and dual Kc method by optimizing single crop coefficient (Kc) and the basal coefficient Kcb, respectively. Both optimized Kcand Kcbwere lower than the adjusted KcFAO56, with optimized Kconly 3% less than the Kc obtained experimentally. ETa estimated by ThM and dual Kc models with optimized crop coefficients (Kc = 1.05 or Kcb = 1.00) had similar high precision (r² >0.79) and accuracy (dm>0.93 and RMSE < 0.30 mm d-1), whereas using the coefficients derived from FAO 56 overestimated ETa in both models.
A Comparison of Symptoms and Signs in Patients with Inflammatory Dry Eye Disease using two Commercially Available Treatment Formulations of Cyclosporine A
Authors: Olafsson Jonatan , Olafsson Snorri , Hammer Hugo Lewi , Tashbayev Behzod , Utheim Øygunn A. , Chen Xiangjun , Raeder Sten , Lagali Neil , Dartt Darlene A. , Utheim Tor P.
Published: August 2021

Purpose: Dry eye (DED) is a multifactorial disease of the ocular surface in which ocular surface inflammation and damage play etiological roles. In the present study, we compared symptoms and signs in patients with DED treated with 0.1% Cyclosporine A (CsA) cationic emulsion (Ikervis, Santen) and 0.05% CsA anionic emulsion (Restasis, Allergan).Methods: Single-center, retrospective, 202 consecutive DED patients were treated with 0.1% CsA cationic emulsion (Ikervis, n=101) or 0.05% CsA anionic emulsion (Restasis, n=101) over six months. Ophthalmological work-up included Ocular Surface Disease Index (OSDI) questionnaire, fluorescein break-up time (FBUT), fluorescein ocular surface staining (OSS), Schirmer’s test, meibum expressibility (ME), and meibum quality (MQ). Results: In both treatment groups, subgroup analysis revealed a significant improvement of OSDI only in patients with severe symptoms at baseline (OSDI 33-100). Ikervis-treated patients with OSDI <23 at baseline had a significant increase in symptoms. OSS and FBUT improved significantly in most subgroups irrespective of Ikervis or Restasis being used. Regression analysis revealed a significant superiority to Restasis with regard to FBUT improvement and superiority to Ikervis in regards ME improvement. Conclusions: We conclude that there is seemingly no substantial difference in efficacy between the two drugs. The strength of Restasis is increased efficacy at improving FBUT and of Ikervis improving ME.
Venetoclax and Azacitidine Therapy in Elder Acute Myeloid Leukemia: A Retrospective Evaluation of Real-World Experience
Authors: Hu Rong-Hua , Su Li , Lan Xiao-Xi , Chang Xiao-Li , Hui Wu-Han , Zhao Hong , Guo Yi-Xian , Wang Guo-Xiang , Sun Wan-Ling
Published: August 2021

Background：To investigate the efficacy of venetoclax combined with azacytidine in the treatment of elderly patients with relapsed and refractory (R/R) acute myeloid leukemia（AML). Methods： The clinical data of 9 elderly AML patients over 65 years old, including 5 with R/R AML, using venetoclax and azacytidine were retrospectively analyzed. Results： Six males and 3 females with a median age of 71 years were included in this study, of which four patients had at least one relapse, and one patient did not get go into remission after 4 cycles of azacytidine monotherapy, deeming it refractory. Four patients had AML with myelodysplasia-related changes (AML-MRC). After 1 to 13 cycles of treatment using venetoclax and azacytidine, one of the 9 patients died early due to long duration of neutropenia and severe pulmonary infection caused by drugs. and six of the remaining 8 patients obtained complete response or complete response with incomplete hematologic recovery (CR/ CRi) , including five R/R patients. One patient did not respond to treatment after two cycles. For the side effects of the treatment, granulocytopenia occurred in all patients, and neutropenia occurred in 8 patients, lasting for an average of 10.5 (6-15) days and was most obvious in the second to third week of treatment. Three patients with TP53 gene mutation positive had following different outcomes. One relapsed patient achieved progression free remission (PFS) for 16 months up to date, and a second patient achieved complete remission but relapsed two months thereafter. Another patient had complete remission in myelology for 4months, but the variant allele fraction value (VAF) gradually increased, indicative that the disease was about to progress. Conclusion：Venetoclax combined with azacytidine regimen in elderly patients is an effective and well tolerated rescue scheme for R/R AML.The patients with TP53 mutation with lower VAF may be benifit from Venetoclax and azacytidine. Severe infection caused by neutropenia is an adverse reaction worthy of attention in the treatment process of the regimen.
Impacts of structural change in global trade on sustainable development
Authors: Wang Jiayu , Wang Ke , Hubacek Klaus , Feng Kuishuang , Shan Yuli , Wei Yi-Ming
Published: August 2021

The 2030 Agenda for Sustainable Development pursues 17 sustainable development goals (SDGs), the achievement of which may be influenced by a country’s role in global supply chains and position in international trade patterns. Global trade changes constantly with an increasing share of flows between developing countries. However, little is known about the impacts of change in trade on multi-dimensions of sustainable development at both global and country levels. Here we assess how structural change in trade during three time periods, between 2004 and 2014, impact 13 SDG indicators in 141 countries or regions. We find that socio-economic indicators (e.g., high- and medium-skilled labor, GDP) are less sensitive to change in trade, compared with resource and environmental indicators (e.g., water consumption, GHG emissions). Moreover, change in trade aggravated inequality among countries. The number of indicators that significantly worsened by change in trade decreased from eight indicators (2004–2007) to one (2011–2014) for high-income and upper-middle-income countries, but increased from five to fourteen for lower-middle-income and low-income countries. Furthermore, change in trade led to a coupling of value added with most resource and environmental indicators for low-income countries, while strengthening decoupling or reducing coupling for other countries.