bluuebunny/crossref_metadata_2025 huggingface dataset:
Mozart's Music of Friends
Authors: Klorman Edward
Published: May 2016

In 1829 Goethe famously described the string quartet as 'a conversation among four intelligent people'. Inspired by this metaphor, Edward Klorman's study draws on a wide variety of documentary and iconographic sources to explore Mozart's chamber works as 'the music of friends'. Illuminating the meanings and historical foundations of comparisons between chamber music and social interplay, Klorman infuses the analysis of sonata form and phrase rhythm with a performer's sensibility. He develops a new analytical method called multiple agency that interprets the various players within an ensemble as participants in stylized social intercourse - characters capable of surprising, seducing, outwitting, and even deceiving one another musically. This book is accompanied by online resources that include original recordings performed by the author and other musicians, as well as video analyses that invite the reader to experience the interplay in time, as if from within the ensemble.
The Graph Music of Morton Feldman
Authors: Cline David
Published: May 2016

Morton Feldman is widely regarded as one of America's greatest composers. His music is famously idiosyncratic, but, in many cases, the way he presented it is also unusual because, in the 1950s and 1960s, he often composed in non-standard musical notations, including a groundbreaking variety on graph paper that facilitated deliberately imprecise specifications of pitch and, at times, other musical parameters. Feldman used this notation, intermittently, over seventeen years, producing numerous graph works that invite analysis as an evolving series. Taking this approach, David Cline marshals a wide range of source materials - many previously unpublished - in clarifying the ideology, organisation and generative history of these graphs and their formative role in the chronicle of post-war music. This assists in pinpointing connections with Feldman's compositions in other formats, works by other composers, notably John Cage, and contemporary currents in painting. Performance practice is examined through analysis of Feldman's non-notated preferences and David Tudor's celebrated interpretations.
Film Copyright in the European Union
Authors: Kamina Pascal
Published: May 2016

Intellectual property issues in the film industry are often highly complex and in today's world are evolving rapidly. In this second edition of Film Copyright in the European Union, Pascal Kamina unravels the complexities of film protection in twenty-eight member states of the European Union, including thirteen new member states who have joined since the first edition. As well as addressing key aspects of film copyright, Pascal Kamina also deals with the protection of film works within the European Union in the context of European harmonisation of copyright laws. Including a new chapter on copyright enforcement, this second edition details the substantial developments in EU law during the last decade, including major cases for the European Court of Justice, new treaties and new directives. This book will interest practitioners, academics and students. The developments on contracts and moral rights will be of particular interest to lawyers outside continental Europe.
Sociolinguistics from the Periphery
Authors: Pietikäinen Sari , Jaffe Alexandra , Kelly-Holmes Helen , Coupland Nikolas
Published: May 2016

This leading team of scholars presents a fascinating book about change: shifting political, economic and cultural conditions; ephemeral, sometimes even seasonal, multilingualism; and altered imaginaries for minority and indigenous languages and their users. The authors refer to this network of interlinked changes as the new conditions surrounding small languages (Sámi, Corsican, Irish and Welsh) in peripheral sites. Starting from the conviction that peripheral sites can and should inform the sociolinguistics of globalisation, the book explores how new modes of reflexivity, more transactional frames for authenticity, commodification of peripheral resources, and boundary-transgression with humour, all carry forward change. These types of change articulate a blurring of binary oppositions between centre and periphery, old and new, and standard and non-standard. Such research is particularly urgent in multilingual small language contexts, where different conceptualisations of language(s), boundaries, and speakers impact on individuals' social, cultural, and economic capital, and opportunities.
Passion and Compassion in Early Christianity
Authors: Wessel Susan
Published: May 2016

This book examines how the early Christian elite articulated and cultivated the affective dimensions of compassion in a Roman world that promoted emotional tranquillity as the path to human flourishing. Drawing upon a wide range of early Christians from both east and west, Wessel situates each author in the broader cultural and intellectual context. The reader is introduced to the diverse conditions in which Christians felt and were urged to feel compassion in exemplary ways, and in which warnings were sounded against the possibilities for distortion and exploitation. Wessel argues that the early Christians developed literary methods and rhetorical techniques to bring about appropriate emotional responses to human suffering. Their success in this regard marks the beginning of affective compassion as a Christian virtue. Comparison with early modern and contemporary philosophers and ethicists further demonstrates the intrinsic worth of the early Christian understanding of compassion.
Ancient Antioch
Authors: De Giorgi Andrea U.
Published: May 2016

From late fourth century BC Seleucid enclave to capital of the Roman east, Antioch on the Orontes was one of the greatest cities of antiquity and served as a hinge between east and west. This book draws on a century of archaeological fieldwork to offer a new narrative of Antioch's origins and growth, as well as its resilience, civic pride, and economic opportunism. Situating the urban nucleus in the context of the rural landscape, this book integrates hitherto divorced cultural basins, including the Amuq Valley and the Massif Calcaire. It also brings into focus the archaeological data, thus proposing a concrete interpretative framework that, grounded in the monuments of Antioch, enables the reader to move beyond text-based reconstructions of the city's history. Finally, it considers the interaction between the environment and the people of the city who shaped this region and forged a distinct identity within the broader Greco-Roman world.
Genoese Trade and Migration in the Spanish Atlantic, 1700–1830
Authors: Brilli Catia
Published: May 2016

The Republic of Genoa was once a major commercial power. Following the Republic's decline in the seventeenth century, Genoese merchants adapted and thrived in the changing Atlantic market. Scholars have examined how other foreign merchant groups operated within the Spanish empire, but until now no one has examined how the Genoese adapted to the challenges of increasing competition in Atlantic trade. Here, Catia Brilli explores how Genoese intermediaries maintained a strong presence in Spanish colonial trade by establishing themselves at the port of Cadiz with its monopoly over American trade, and through gradually consolidating strong commercial ties with the Río de la Plata. Situated at the intersection of European, Atlantic, and Latin American history and making extensive use of Spanish, Italian, and Argentinian sources, Genoese Trade and Migration in the Spanish Atlantic, 1700–1830 provides a unique perspective on eighteenth- and early nineteenth-century transatlantic trade.
Marketing Sovereign Promises
Authors: Cox Gary W.
Published: May 2016

How did England, once a minor regional power, become a global hegemon between 1689 and 1815? Why, over the same period, did she become the world's first industrial nation? Gary W. Cox addresses these questions in Marketing Sovereign Promises. The book examines two central issues: the origins of the great taxing power of the modern state and how that power is made compatible with economic growth. Part I considers England's rise after the revolution of 1689, highlighting the establishment of annual budgets with shutdown reversions. This core reform effected a great increase in per capita tax extraction. Part II investigates the regional and global spread of British budgeting ideas. Cox argues that states grew only if they addressed a central credibility problem afflicting the Ancien Régime - that rulers were legally entitled to spend public revenue however they deemed fit.
The Inner Workings of Life
Authors: Voit Eberhard O.
Published: May 2016

Living systems are dynamic and extremely complex and their behaviour is often hard to predict by studying their individual parts. Systems biology promises to reveal and analyse these highly connected, regulated and adaptable systems, using mathematical modelling and computational analysis. This new systems approach is already having a broad impact on biological research and has potentially far-reaching implications for our understanding of life. Written in an informal and non-technical style, this book provides an accessible introduction to systems biology. Self-contained vignettes each convey a key theme and are intended to enlighten, provoke and interest readers of different academic disciplines, but also to offer new insight to those working in the field. Using a minimum amount of jargon and no mathematics, Voit manages to convey complex ideas and give the reader a genuine sense of the excitement that systems biology brings with it, as well as the current challenges and opportunities.
George Herbert: 100 Poems
Authors: Herbert George
Published: May 2016

George Herbert (1593–1633) is widely regarded as the greatest devotional poet in the English language. His profound influence can be seen in the lasting popularity of his verse. This selection of one hundred lyric poems by Herbert is designed for readers to enjoy the beauty, spirituality, accessibility and humanity of his best verse. Each poem uses the authoritative text from the acclaimed Cambridge edition of Herbert's poems, presenting them in their original spelling in a clear and elegant format. The selection includes such well-loved lyric verses as 'Love bade me welcome', 'Let all the world in ev'ry corner sing', 'I struck the board and cry'd, No more' and 'Sweet day, so cool, so calm, so bright'. A preface by Helen Wilcox, editor of the Cambridge edition, celebrates the key features of Herbert's poetry for a new generation of readers.
New York State Public Health System Response to Hurricane Sandy: An Analysis of Survey Feedback
Authors: Shipp Hilts Asante , Mack Stephanie , Li Yunshu , Eidson Millicent , Nguyen Trang , Birkhead Guthrie S.
Published: May 2016

Objective

The objective was to provide a broad spectrum of New York State and local public health staff the opportunity to contribute anonymous feedback on their own and their agencies’ preparedness and response to Hurricane Sandy, perceived challenges, and recommendations for preparedness improvement.

Methods

In 2015, 2 years after Hurricane Sandy, public health staff who worked on Hurricane Sandy response were identified and were provided a link to the anonymous survey. Quantitative analyses were used for survey ratings and qualitative content analyses were used for open-ended questions.

Results

Surveys were completed by 129 local health department (LHD) staff in 3 counties heavily impacted by Sandy (Nassau, Suffolk, and Westchester) and 69 staff in the New York State Department of Health who supported the LHDs. Staff agreed that their Hurricane Sandy responsibilities were clearly defined and that they had access to adequate information to perform their jobs. Challenges were reported in the operational, communication, service interruptions, and staff categories, with LHD staff also reporting challenges with shelters.

Conclusions

New York local and state public health staff indicated that they were prepared for Hurricane Sandy. However, their feedback identified specific challenges and recommendations that can be addressed to implement improved preparedness and response strategies. (Disaster Med Public Health Preparedness. 2016;10:454–462)
Head-to-Modifier Reanalysis: The Rise of the Adjectival QuantifierVieland the Loss of Genitive Case Assignment
Authors: Sapp Christopher , Roehrs Dorian
Published: May 2016

The quantifiervielchanges from exhibiting properties of a head in Old High German to exhibiting properties of a modifier in Modern German. This is accompanied by changes in word order vis-à-vis its quantified constituent and the loss of the ability to assign genitive case to some of the quantified constituents. Assuming that quantifying expressions may have various syntactic representations, we argue thatvieldevelops from a quantifying noun to a particle in Card0to an adjectival quantifier in Spec, CardP, and that this structural change in the position ofvielcan account in part for the morphosyntactic properties of the quantified element. The development ofvielfrom a quantifying noun to a quantifying particle—a case of head-to-head reanalysis—is typical of grammaticalization. However, the change from a particle to an adjectival quantifier represents head-to-specifier reanalysis, which we relate to degrammaticalization due to analogy with other inflected elements of the DP. The change in word order and case properties of the quantified constituent represents a third type of reanalysis, whereby an embedded nominal undergoes downward reanalysis. Depending on the structural size—that is, whether a DP-layer is present or not—the dependent nominal either integrates into the matrix nominal agreeing withvielor, if too large, it takes up a new embedded position as a complement of the matrix head noun, retaining genitive. We demonstrate that in each case, the morphological change lags behind the syntactic reanalysis.*
Mexico City Hosts a Course on Remote Sensing for Latin Americans
Authors: Grutter M. , Antuña-Marrero Juan , Rudamas Carlos
Published: May 2016

Course on Remote Sensing Techniques Applied to Atmospheric Chemistry; Mexico City, Mexico, 7–11 December 2015
Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer
Authors: Taniguchi T , Iizumi Y , Watanabe M , Masuda M , Morita M , Aono Y , Toriyama S , Oishi M , Goi W , Sakai T
Published: May 2016

Resveratrol has various attractive bioactivities, such as prevention of cancer, neurodegenerative disorders, and obesity-related diseases. Therefore, identifying its direct binding proteins is expected to discover druggable targets. Sirtuin 1 and phosphodiesterases have so far been found as the direct molecular targets of resveratrol. We herein identified 11 novel resveratrol-binding proteins, including the DEAD (Asp-Glu-Ala-Asp) box helicase 5 (DDX5, also known as p68), using resveratrol-immobilized beads. Treatment with resveratrol induced degradation of DDX5 in prostate cancer cells. Depletion of DDX5 caused apoptosis by inhibiting mammalian target of rapamycin complex 1 (mTORC1) signaling. Moreover, knockdown of DDX5 attenuated the inhibitory activities of resveratrol against mTORC1 signaling and cancer cell growth. These data show that resveratrol directly targets DDX5 and induces cancer cell death by inhibiting the mTORC1 pathway.
PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers
Authors: Eastman Richard T. , Khine Pwint , Huang Ruili , Thomas Craig J. , Su Xin-zhuan
Published: May 2016

Treatment of the symptomatic asexual stage of Plasmodium falciparum relies almost exclusively on artemisinin (ART) combination therapies (ACTs) in endemic regions. ACTs combine ART or its derivative with a long-acting partner drug to maximize efficacy during the typical three-day regimen. Both laboratory and clinical studies have previously demonstrated that the common drug resistance determinants P. falciparum chloroquine resistance transporter (PfCRT) and multidrug resistance transporter (PfMDR1) can modulate the susceptibility to many current antimalarial drugs and chemical compounds. Here we investigated the parasite responses to dihydroartemisinin (DHA) and various Ca2+ and Na+ channel blockers and showed positively correlated responses between DHA and several channel blockers, suggesting potential shared transport pathways or mode of action. Additionally, we demonstrated that PfCRT and PfMDR1 could also significantly modulate the pharmacodynamic interactions of the compounds and that the interactions were influenced by the parasite genetic backgrounds. These results provide important information for better understanding of drug resistance and for assessing the overall impact of drug resistance markers on parasite response to ACTs.
Is lymphovascular invasion a powerful predictor for biochemical recurrence in pT3 N0 prostate cancer? Results from the K-CaP database
Authors: Park Yong Hyun , Kim Yejin , Yu Hwanjo , Choi In Young , Byun Seok-Soo , Kwak Cheol , Chung Byung Ha , Lee Hyun Moo , Kim Choung Soo , Lee Ji Youl
Published: May 2016

To assess the impact of lymphovascular invasion (LVI) on the risk of biochemical recurrence (BCR) in pT3 N0 prostate cancer, clinical data were extracted from 1,622 patients with pT3 N0 prostate cancer from the K-CaP database. Patients with neoadjuvant androgen deprivation therapy (n = 325) or insufficient pathologic or follow-up data (n = 87) were excluded. The primary endpoint was the oncologic importance of LVI, and the secondary endpoint was the hierarchical relationships for estimating BCR between the evaluated variables. LVI was noted in 260 patients (21.5%) and was significantly associated with other adverse clinicopathologic features. In the multivariate Cox regression analysis, LVI was significantly associated with an increased risk of BCR after adjusting for known prognostic factors. In the Bayesian belief network analysis, LVI and pathologic Gleason score were found to be first-degree associates of BCR, whereas prostate-specific antigen (PSA) level, seminal vesicle invasion, perineural invasion, and high-grade prostatic intraepithelial neoplasia were considered second-degree associates. In the random survival forest, pathologic Gleason score, LVI, and PSA level were three most important variables in determining BCR of patients with pT3 N0 prostate cancer. In conclusion, LVI is one of the most powerful adverse prognostic factors for BCR in patients with pT3 N0 prostate cancer.
Mobility and Muscle Strength Together are More Strongly Correlated with Falls in Suburb-Dwelling Older Chinese
Authors: Wang Xiuyang , Ma Yixuan , Wang Jiazhong , Han Peipei , Dong Renwei , Kang Li , Zhang Wen , Shen Suxing , Wang Jing , Li Dongfang , Zhou Maoran , Wang Liancheng , Niu Kaijun , Guo Qi
Published: May 2016

Falls are common in older adults and result in adverse outcomes. Impaired mobility and poor muscle strength have been consistently identified as the main contributors to falls. We choose three easy-to-perform tests (i.e. Timed Up and Go test (TUGT), walking speed (WS) and grip strength (GS)) in order to assess mobility and muscle strength to further define their relationship with falls. This study is cross-sectional, consisting of 1092 residents over 60-year-old; 589 were female. 204 (18.68%) participants reported falling at least once in the past year. It was found that, of the three tests evaluated independently, a TUGT < 9.1750 s had the strongest association with fewer falls. When evaluating these tests as pairs, the combination of a TUGT < 9.1750 s and a WS < 0.9963 m/s was the best protective indicator of falls after adjusting for age, sex and other variables. When evaluating all three tests in conjunction with each other, the combination of a TUGT < 9.1750 s, a WS < 0.9963 m/s and a GS > 0.3816 was most correlated with less possibility of falls. The combination of a better TUGT performance, a stronger GS and a slower WS is the most strongly correlated with less possibility of falls.
Social correlates of the dominance rank and long-term cortisol levels in adolescent and adult male rhesus macaques (Macaca mulatta)
Authors: Feng Xiaoli , Wu Xujun , Morrill Ryan J. , Li Zhifei , Li Chunlu , Yang Shangchuan , Li Zhaoxia , Cui Ding , Lv Longbao , Hu Zhengfei , Zhang Bo , Yin Yong , Guo Liyun , Qin Dongdong , Hu Xintian
Published: May 2016

A common pattern in dominance hierarchies is that some ranks result in higher levels of psychosocial stress than others. Such stress can lead to negative health outcomes, possibly through altered levels of stress hormones. The dominance rank-stress physiology relationship is known to vary between species; sometimes dominants show higher levels of glucocorticoid stress hormones, whereas in other cases subordinates show higher levels. It is less clear how this relationship varies between groups of different ages or cultures. In this study, we used long-term cortisol measurement methods to compare the effect of rank on cortisol levels in adult and adolescent male rhesus macaques. In the adult groups, subordinates had significantly higher cortisol levels. In the adolescents, no significant correlation between cortisol and status was found. Further analysis demonstrated that the adult hierarchy was stricter than that of the adolescents. Adult subordinates received extreme aggression more frequently than dominants and this class of behavior was positively correlated with cortisol; by contrast, adolescents showed neither trend. Together, these findings provide evidence for a cortisol-rank relationship determined by social factors, namely, despotism of the group and highlight the importance of group-specific social analysis when comparing or combining results obtained from different groups of animals.
Asymmetric masks for laboratory-based X-ray phase-contrast imaging with edge illumination
Authors: Endrizzi Marco , Astolfo Alberto , Vittoria Fabio A. , Millard Thomas P. , Olivo Alessandro
Published: May 2016

We report on an asymmetric mask concept that enables X-ray phase-contrast imaging without requiring any movement in the system during data acquisition. The method is compatible with laboratory equipment, namely a commercial detector and a rotating anode tube. The only motion required is that of the object under investigation which is scanned through the imaging system. Two proof-of-principle optical elements were designed, fabricated and experimentally tested. Quantitative measurements on samples of known shape and composition were compared to theory with good agreement. The method is capable of measuring the attenuation, refraction and (ultra-small-angle) X-ray scattering, does not have coherence requirements and naturally adapts to all those situations in which the X-ray image is obtained by scanning a sample through the imaging system.
Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes
Authors: Gandini Francesca , Achilli Alessandro , Pala Maria , Bodner Martin , Brandini Stefania , Huber Gabriela , Egyed Balazs , Ferretti Luca , Gómez-Carballa Alberto , Salas Antonio , Scozzari Rosaria , Cruciani Fulvio , Coppa Alfredo , Parson Walther , Semino Ornella , Soares Pedro , Torroni Antonio , Richards Martin B. , Olivieri Anna
Published: May 2016

Rare mitochondrial lineages with relict distributions can sometimes be disproportionately informative about deep events in human prehistory. We have studied one such lineage, haplogroup R0a, which uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, from Europe to India. We conclude that: (1) the lineage ancestral to R0a is more ancient than previously thought, with a relict distribution across the Mediterranean/Southwest Asia; (2) R0a has a much deeper presence in Arabia than previously thought, highlighting the role of at least one Pleistocene glacial refugium, perhaps on the Red Sea plains; (3) the main episode of dispersal into Eastern Africa, at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions from one or more refugia in Arabia; (4) there was likely a minor Late Glacial/early postglacial dispersal from Arabia through the Levant and into Europe, possibly alongside other lineages from a Levantine refugium; and (5) the presence of R0a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ~3 ka between Africa and the Indian Ocean led to some gene flow even further afield, into Iran, Pakistan and India.
Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells
Authors: Reinhard Nathalie R. , van Helden Suzanne F. , Anthony Eloise C. , Yin Taofei , Wu Yi I. , Goedhart Joachim , Gadella Theodorus W. J. , Hordijk Peter L.
Published: May 2016

Endothelial cells line the vasculature and are important for the regulation of blood pressure, vascular permeability, clotting and transendothelial migration of leukocytes and tumor cells. A group of proteins that that control the endothelial barrier function are the RhoGTPases. This study focuses on three homologous (>88%) RhoGTPases: RhoA, RhoB, RhoC of which RhoB and RhoC have been poorly characterized. Using a RhoGTPase mRNA expression analysis we identified RhoC as the highest expressed in primary human endothelial cells. Based on an existing RhoA FRET sensor we developed new RhoB/C FRET sensors to characterize their spatiotemporal activation properties. We found all these RhoGTPase sensors to respond to physiologically relevant agonists (e.g. Thrombin), reaching transient, localized FRET ratio changes up to 200%. These RhoA/B/C FRET sensors show localized GEF and GAP activity and reveal spatial activation differences between RhoA/C and RhoB. Finally, we used these sensors to monitor GEF-specific differential activation of RhoA/B/C. In summary, this study adds high-contrast RhoB/C FRET sensors to the currently available FRET sensor toolkit and uncover new insights in endothelial and RhoGTPase cell biology. This allows us to study activation and signaling by these closely related RhoGTPases with high spatiotemporal resolution in primary human cells.
Early change in left atrial function in patients treated with anthracyclines assessed by real-time three-dimensional echocardiography
Authors: Shi Jing , Guo Ye , Cheng Leilei , Song Feiyan , Shu Xianhong
Published: May 2016

Real-time three-dimensional echocardiography(RT-3DE) has allowed a better assessment of LA volumes and function. We sought to assess the early change in left atrial size and function in patients treated with anthracyclines using RT-3DE. 61 patients aged 44.9 ± 11.9 years with large B-cell non-Hodgkin lymphoma treated with doxorubicin were studied. Blood collection and echocardiography were performed at baseline and 1 day after completion of the chemotherapy. Global longitudinal strain (GLS), maximum, minimum and pre-atrial contraction LA volumes were measured and reservoir, conduit and booster pump function were assessed. Despite normal LVEF, passive emptying percent of total emptying (0.51 ± 0.14 vs. 0.40 ± 0.12, P < 0.001) and passive emptying index (0.29 ± 0.10 vs. 0.23 ± 0.06, P < 0.001) were remarkably reduced compared to baseline values, while active emptying percent of total emptying (0.49 ± 0.14 vs. 0.60 ± 0.12, P < 0.001) and active emptying index (0.41 ± 0.16 vs. 0.47 ± 0.16, P = 0.048) were increased. GLS (−21.64 ± 2.83 vs. −17.30 ± 2.50) was markedly reduced, cTnT levels was elevated from 0.005 ± 0.004 to 0.020 ± 0.026 ng/mL at the completion of chemotherapy (P all  < 0.001). Early LA functional change occur after doxorubicin exposure in patients with preserved LVEF, which could be detected by RT-3DE.
Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions
Authors: Minamikawa Takeo , Matsuo Hisataka , Kato Yoshiyuki , Harada Yoshinori , Otsuji Eigo , Yanagisawa Akio , Tanaka Hideo , Takamatsu Tetsuro
Published: May 2016

5-aminolevulinic acid (5-ALA)-based fluorescence diagnosis is now clinically applied for accurate and ultrarapid diagnosis of malignant lesions such as lymph node metastasis during surgery. 5-ALA-based diagnosis evaluates fluorescence intensity of a fluorescent metabolite of 5-ALA, protoporphyrin IX (PPIX); however, the fluorescence of PPIX is often affected by autofluorescence of tissue chromophores, such as collagen and flavins. In this study, we demonstrated PPIX fluorescence estimation with autofluorescence elimination for 5-ALA-based fluorescence diagnosis of malignant lesions by simplified and optimized multispectral imaging. We computationally optimized observation wavelength regions for the estimation of PPIX fluorescence in terms of minimizing prediction error of PPIX fluorescence intensity in the presence of typical chromophores, collagen and flavins. By using the fluorescence intensities of the optimized wavelength regions, we verified quantitative detection of PPIX fluorescence by using chemical mixtures of PPIX, flavins and collagen. Furthermore, we demonstrated detection capability by using metastatic and non-metastatic lymph nodes of colorectal cancer patients. These results suggest the potential and usefulness of the background-free estimation method of PPIX fluorescence for 5-ALA-based fluorescence diagnosis of malignant lesions and we expect this method to be beneficial for intraoperative and rapid cancer diagnosis.
Novel structural aspect of the diatom thylakoid membrane: lateral segregation of photosystem I under red-enhanced illumination
Authors: Bína David , Herbstová Miroslava , Gardian Zdenko , Vácha František , Litvín Radek
Published: May 2016

Spatial segregation of photosystems in the thylakoid membrane (lateral heterogeneity) observed in plants and in the green algae is usually considered to be absent in photoautotrophs possessing secondary plastids, such as diatoms. Contrary to this assumption, here we show that thylakoid membranes in the chloroplast of a marine diatom, Phaeodactylum tricornutum, contain large areas occupied exclusively by a supercomplex of photosystem I (PSI) and its associated Lhcr antenna. These membrane areas, hundreds of nanometers in size, comprise hundreds of tightly packed PSI-antenna complexes while lacking other components of the photosynthetic electron transport chain. Analyses of the spatial distribution of the PSI-Lhcr complexes have indicated elliptical particles, each 14 × 17 nm in diameter. On larger scales, the red-enhanced illumination exerts a significant effect on the ultrastructure of chloroplasts, creating superstacks of tens of thylakoid membranes.
Synthesis of gold(iii) ← gold(i)–NHC through disproportionation: the role of gold(i)–NHC in the induction of apoptosis in HepG2 cells
Authors: Nandy Abhishek , Samanta Tapastaru , Mallick Sumana , Mitra Partha , Seth Saikat Kumar , Saha Krishna Das , Al-Deyab Salem S. , Dinda Joydev
Published: May 2016

The anticancer activities of novel Au(i) and Au(iii)–NHC complexes based on 2-[(6-methylpyridin-2-yl)]imidazo[1,5-a]pyridin-4-ylium hexafluorophosphate have been investigated.
Role of the non-conserved amino acid asparagine 285 in the glycone-binding pocket of Neosartorya fischeri β-glucosidase
Authors: Ramachandran Priyadharshini , Jagtap Sujit Sadashiv , Patel Sanjay K. S. , Li Jinglin , Chan Kang Yun , Lee Jung-Kul
Published: May 2016

Neosartorya fischeriβ-glucosidase (NfBGL595) is distinguished from other BGLs by its high turnover forp-nitrophenyl β-d-glucopyranoside (pNPG) and flavones.
Modification of a disposable pencil graphite electrode with multiwalled carbon nanotubes: application to electrochemical determination of diclofenac sodium in some pharmaceutical and biological samples
Authors: Fard Golnaz Parvizi , Alipour Esmaeel , Ali Sabzi Reza Emam
Published: May 2016

A MWCNTs/PGE was developed as an electrochemical sensor and used for the determination of diclofenac sodium (DIC).
NIR spectrophotometry with integrated beam splitter as a process analytical technology for meat composition analysis
Authors: Dixit Y. , Casado-Gavalda Maria P. , Cama-Moncunill R. , Markiewicz-Keszycka Maria , Cruise P. , Jacoby Franklyn , Cullen P. J. , Sullivan Carl
Published: May 2016

Meat composition analysis with a beam splitter integrated NIR spectrophotometer.
Dual stimuli-responsive smart beads that allow “on–off” manipulation of cancer cells
Authors: Kim Young-Jin , Kim Soo Hyeon , Fujii Teruo , Matsunaga Yukiko T.
Published: May 2016

Temperature- and electric field-responsive polymer-conjugated polystyrene beads, termed smart beads, are designed to isolate cancer cells.
An unprecedented zero field neodymium(iii) single-ion magnet based on a phosphonic diamide
Authors: Gupta Sandeep K. , Rajeshkumar Thayalan , Rajaraman Gopalan , Murugavel Ramaswamy
Published: May 2016

A pseudo-D5h symmetric Nd(iii)-complex exhibits zero-field SIM behavior as a result of a strong axial crystal field, stabilization of the rare mJ = |±9/2〉 ground state, and small transverse anisotropy.
Chemical vapor deposition of MoS2 layers from Mo–S–C–O–H system: thermodynamic modeling and validation
Authors: Dhar Sukanya , Kranthi Kumar V. , Choudhury Tanushree H. , Shivashankar S. A. , Raghavan S.
Published: May 2016

To determine growth windows for CVD of contamination-free layered MoS2, thermodynamic modelling and experimental validation of the Mo–S–C–O–H system are conducted.
On the gas phase fragmentation of protonated uracil: a statistical perspective
Authors: Rossich Molina Estefanía , Salpin Jean-Yves , Spezia Riccardo , Martínez-Núñez Emilio
Published: May 2016

The major fragmentation pathways of protonated uracil calculated in this work using statistical methods agree with mass spectrometry experiments.
Plasticization-resistant Ni2(dobdc)/polyimide composite membranes for the removal of CO2 from natural gas
Authors: Bachman Jonathan E. , Long Jeffrey R.
Published: May 2016

Incorporating metal–organic framework nanoparticles into polyimides yields composite membranes that have improved performance for purifying natural gas.
Computer calculations across time and length scales in photovoltaic solar cells
Authors: Bernardi Marco , Grossman Jeffrey C.
Published: May 2016

Photovoltaic (PV) solar cells convert solar energy to electricity through a cascade of microscopic processes spanning over 10 order of magnitudes of time and length. We review the computational methods available to study PV solar cells, focusing on recent advances and open problems.
Evaluation of interference filters for spectral discrimination in solution-cathode glow discharge optical emission spectrometry
Authors: Schwartz Andrew J. , Ray Steven J. , Hieftje Gary M.
Published: May 2016

Solution-cathode glow discharge optical emission performance is evaluated with interference filters and critically compared to a traditional spectrometer.
Theoretical simulations of nanostructures self-assembled from copolymer systems
Authors: Xu Zhanwen , Lin Jiaping , Zhang Qian , Wang Liquan , Tian Xiaohui
Published: May 2016

This article provides an overview of recent simulation investigations of the nanostructures and structure–property relationships in copolymer systems.
Mathematical methods on atomic force microscope cantilever systems
Authors: Sumetpipat Kanes , Baowan Duangkamon , Cox Barry J. , Hill James M.
Published: May 2016

Mathematical modelling, comprising Lennard–Jones potential and calculus of variations, is utilized to obtain the energy equations arising from AFM probe and substrate, leading to deflection equations of AFM cantilever.
Enhancement of magnetic properties in hard/soft CoFe2O4/Fe3O4 nanocomposites
Authors: Zeng Qingzi , Jiang Dongmei , Yang Shengbin
Published: May 2016

Significant enhancements of Mr/Ms ratio, Hc and (BH)max have been achieved in the CoFe2O4/Fe3O4 nanocomposites compared with the pure CoFe2O4.
Bis-arylsulfenyl- and bis-arylselanyl-benzo-2,1,3-thiadiazoles: synthesis and photophysical characterization
Authors: Balaguez Renata A. , Ricordi Vanessa G. , Duarte Rodrigo C. , Toldo Josene M. , Santos Cristtofer M. , Schneider Paulo H. , Gonçalves Paulo F. B. , Rodembusch Fabiano S. , Alves Diego
Published: May 2016

Bis-arylsulfenyl- and bis-arylselanyl-benzo-2,1,3-thiadiazoles were synthesized in good yields by copper-catalysed cross-coupling reaction of arylthiols or diaryl diselenides with the commercially available 4,7-dibromobenzo[c][1,2,5]thiadiazole.
DABCO-based ionic liquids: green and recyclable catalysts for the synthesis of barbituric and thiobarbituric acid derivatives in aqueous media
Authors: Seyyedi Narges , Shirini Farhad , Nikoo Langarudi Mohaddeseh Safarpoor
Published: May 2016

A new and straightforward method for the synthesis of 5-arylidine barbituric and thiobarbituric acids through a reaction between barbituric acid and its thio-analogue with aldehydes using [DABCO](SO3H)2(HSO4)2) as an efficient catalyst has been reported.
On the origins of the elasticity of cellulose nanofiber nanocomposites and nanopapers: a micromechanical approach
Authors: Martoïa F. , Dumont P. J. J. , Orgéas L. , Belgacem M. N. , Putaux J.-L.
Published: May 2016

The elastic properties of cellulose nanofibril (NFC) nanocomposites and nanopapers are predicted by a multiscale network model that shows that the deformation mechanisms are governed by the bonds between rigid NFC segments and in the kinked regions.
A comparative study on the functionality of S- and P-based lubricant additives by combined first principles and experimental analysis
Authors: Righi M. C. , Loehlé S. , De Barros Bouchet M. I. , Mambingo-Doumbe S. , Martin J. M.
Published: May 2016

Sulfur reduces the adhesion and shear strength of iron more effectively than phosphorus. The surface chemistry, well described by first principles calculations, impacts macroscale tribological properties.
An eco-friendly physicocultural-based rapid synthesis of selenium nanoparticles
Authors: Shirsat Shubhangi , Kadam Ambadas , Jadhav Vijaykumar V. , Zate Manohar K. , Naushad Mu. , Pawar B. N. , Mane Rajaram S. , Kim Kwang Ho
Published: May 2016

A rapid synthesis of stable and smaller sized Se NPs was achieved in tryptic soya medium maintained at pH ∼9, temperature ∼50 °C, and a 9 mM Se oxyion concentration.
DNA-mediated cell surface engineering for multiplexed glycan profiling using MALDI-TOF mass spectrometry
Authors: He Ziyi , Chen Qiushui , Chen Fengming , Zhang Jie , Li Haifang , Lin Jin-Ming
Published: May 2016

A MALDI-TOF MS based approach is developed for multiplexed profiling of cell surface glycans using a DNA-mediated cell surface engineering strategy.
Direct observation of realistic-temperature fuel combustion mechanisms in atomistic simulations
Authors: Bal Kristof M. , Neyts Erik C.
Published: May 2016

Advanced accelerated molecular dynamics simulations provide a detailed atomic-level picture of combustion at realistic temperatures and pressures.
Eradicating mass spectrometric glycan rearrangement by utilizing free radicals
Authors: Desai Nikunj , Thomas Daniel A. , Lee Jungeun , Gao Jinshan , Beauchamp J. L.
Published: May 2016

We designed and synthesized a methylated free radical activated glycan sequencing reagent (Me-FRAGS) for eliminating mass spectrometric glycan rearrangement.
Photochemical reduction of carbon dioxide coupled with water oxidation using various soft-oxometalate (SOM) based catalytic systems
Authors: Das Santu , Biswas Subharanjan , Balaraju Tuniki , Barman Soumitra , Pochamoni Ramudu , Roy Soumyajit
Published: May 2016

We report soft-oxometalate catalytic systems based on various metal oxide catalysts to oxidize H2O and utilize the generated H+s and e−s for reduction of CO2 with a TON of 1366 (effectively 1.4 x 106).
Renewable graphene-like nitrogen-doped carbon nanosheets as supercapacitor electrodes with integrated high energy–power properties
Authors: Tian Weiqian , Gao Qiuming , Zhang Liming , Yang Chunxiao , Li Zeyu , Tan Yanli , Qian Weiwei , Zhang Hang
Published: May 2016

Renewable graphene-like nitrogen-doped carbon nanosheets were constructed from layered shrimp shells with integrated high energy–power supercapacitive properties.
Magnetic resonance imaging/fluorescence dual modality protocol using designed phosphonate ligands coupled to superparamagnetic iron oxide nanoparticles
Authors: Lam Tina , Avti Pramod K. , Pouliot Philippe , Tardif Jean-Claude , Rhéaume Éric , Lesage Frederic , Kakkar Ashok
Published: May 2016

Easily dispersed in water and fluorescent. Very high r2 and r2* relaxivities. Dye does not influence cell viability of the probe.
A dual-phase architecture for efficient amplified spontaneous emission in lead iodide perovskites
Authors: Neutzner Stefanie , Srimath Kandada Ajay Ram , Lanzani Guglielmo , Petrozza Annamaria
Published: May 2016

We report a way to overcome Auger recombination in lead iodide perovskites by investigating the domain structure forming below the phase transition temperature.
Design, synthesis, chemical stability, packing, cyclic voltammetry, ionisation potential, and charge transport of [1]benzothieno[3,2-b][1]benzothiophene derivatives
Authors: Ruzié Christian , Karpinska Jolanta , Laurent Anne , Sanguinet Lionel , Hunter Simon , Anthopoulos Thomas D. , Lemaur Vincent , Cornil Jérôme , Kennedy Alan R. , Fenwick Oliver , Samorì Paolo , Schweicher Guillaume , Chattopadhyay Basab , Geerts Yves Henri
Published: May 2016

Unexpected effect of structure on electronic propeties.
Long-Term Effect of Endoscopic Sympathetic Nerve Reconstruction for Side Effects after Endoscopic Sympathectomy
Authors: Telaranta Timo , Rantanen Tuomo
Published: May 2016

Background Endoscopic thoracic sympathectomy (ETS) is an effective treatment for primary hyperhidrosis. However, compensatory sweating (CS) may occur in many patients. Sympathetic nerve reconstruction (SNR) can be used to counteract severe CS, but the studies on the effects of SNR are few.

Patients and Methods Nineteen out of 150 SNR patients were contacted by employing a long-term questionnaire. In this questionnaire, different kinds of sweating were evaluated using a four-graded symptom analysis and the visual analog scale before ETS, after ETS, and after SNR.

Results The mean age of the 16 male and 3 female patients at the SNR was 32 years. The mean follow-up was 87 months. According to the long-term questionnaire, the benefit was either excellent (4 patients, 21%), good (3 patients, 15.8%), or reasonable (7 patients, 36.8%) in 14 patients (73.8%), while the benefit was questionable in 1 patient (5.3%). For three patients (15.8%), no benefit was found, and in one patient (5.3%), the situation had deteriorated.

Conclusions Improvement in the side effects of ETS after SNR was found in nearly 75% of the patients. This indicates that SNR can be considered as an alternative treatment for patients with severe CS after ETS that is unresponsive to conservative treatment.
Conservative dissipation: How important is the Jacobi identity in the dynamics?
Authors: Caligan C. E. , Chandre C.
Published: May 2016

Hamiltonian dynamics are characterized by a function, called the Hamiltonian, and a Poisson bracket. The Hamiltonian is a conserved quantity due to the anti-symmetry of the Poisson bracket. The Poisson bracket satisfies the Jacobi identity which is usually more intricate and more complex to comprehend than the conservation of the Hamiltonian. Here, we investigate the importance of the Jacobi identity in the dynamics by considering three different types of conservative flows in ℝ3: Hamiltonian, almost-Poisson, and metriplectic. The comparison of their dynamics reveals the importance of the Jacobi identity in structuring the resulting phase space.
Fabrication and characterization of CuxSi1−x films on Si (111) and Si (100) by pulsed laser deposition
Authors: Zhang Song , Wu Jun , He Zhiqiang , Xie Jun , Lu Jingqi , Tu Rong , Zhang Lianmeng , Shi Ji
Published: May 2016

The CuxSi1−x thin films have been successfully fabricated by pulsed laser deposition (PLD). The influences of laser energy fluency (I0) and deposition temperature (Td) on the phase structure were investigated. The results show that Cu deposited on Si (001) at I0 = 0.5-2.0 J/cm2, and η”-Cu3Si formed on Si (111) at I0 = 1.0-2.0 J/cm2. The films were consisted of Cu, η’-Cu3Si, ε-Cu15Si4 and δ-Cu0.83Si0.17 at Td = 100-500 °C on Si (001). The films were the single phase of η-Cu3Si at Td = 700 °C. In the case of Si (111), the phase structures transformed from Cu to Cu + η’-Cu3Si to η’-Cu3Si to η’-Cu3Si + η-Cu3Si with the increasing of Td. Rectangular grains were formed on Si (001), whereas triangular grains on Si (111). Cu (001) film was epitaxially grown on Si (001) at I0 = 1.5 J/cm2 and Td = 20 °C. η-Cu3Si (001) epitaxial layer was formed on Si (111) at I0 = 1.5 J/cm2 and Td = 700 °C. The epitaxial relationships of Cu (001)[100]//Si (001)[110] and η-Cu3Si (001)[-110]//Si (111)[11-2] were identified.
Strain field of the monovacancy in silicene: First-principles study
Authors: Li Rui , Liu Zhongli , Ma Wenqiang , Tan Yonggang
Published: May 2016

The in-plane strain fields of single-vacancy silicene with different monovacancy (MV) concentrations, as well as the corresponding electronic band structures, are investigated by using the first-principle calculations. Firstly the self-healing MV is found to be the most stable ground structure in silicene, which is different from the other 2D hexagonal honeycomb materials, e.g. graphene, h-BN. In the isolated MV center, the bonds along the pentagons are compressed, creating a compress field, and those close to the distorted hexagons are stretched, creating a stretch field. As the MV concentration increasing, the interacted compress field tends to corrugate the defected silicene, while the interacted stretch field impacts little on the low-buckled structure. Especially, the corrugation presents in those supercells with small MV concentration, just as the (4, 5), (4, 6), (4, 7), (4, 8) supercells. The corrugations approach zero at both low and high MV concentrations, and the (4, 6) supercell with a MV concentration of about 0.021, has a peak value of 3.23Å. The electronic calculations show that the linear dispersion at Γ point in pristine silicene is broken by the lower lattice symmetry of the self-healing MV reconstruction, which translates it into metal as well.
Richardson-Schottky transport mechanism in ZnS nanoparticles
Authors: Ali Hassan , Khan Usman , Rafiq M. A. , Falak Attia , Narain Adeela , Jing Tang , Xu Xiulai
Published: May 2016

We report the synthesis and electrical transport mechanism in ZnS semiconductor nanoparticles. Temperature dependent direct current transport measurements on the compacts of ZnS have been performed to investigate the transport mechanism for temperature ranging from 300 K to 400 K. High frequency dielectric constant has been used to obtain the theoretical values of Richardson-Schottky and Poole-Frenkel barrier lowering coefficients. Experimental value of the barrier lowering coefficient has been calculated from conductance-voltage characteristics. The experimental value of barrier lowering coefficient βexp lies close to the theoretical value of Richardson-Schottky barrier lowering coefficient βth,RS showing Richardson-Schottky emission has been responsible for conduction in ZnS nanoparticles for the temperature range studied.
Soliton collisions in soft magnetic nanotube with uniaxial anisotropy
Authors: Usov N. A.
Published: May 2016

The structure of stable magnetic solitons of various orders in soft magnetic nanotube with uniaxial magnetic anisotropy has been studied using numerical simulation. Solitons of even order are immobile in axially applied magnetic field. Odd solitons show decreased mobility with respect to that of head-to head domain wall. Solitons of various orders can participate in nanotube magnetization reversal process. Various coalescence and decomposition processes in soliton assembly are considered. It is shown that the general magnetization state of magnetic nanotube consists of chains of magnetic solitons of various orders.