bluuebunny/crossref_metadata_2025 huggingface dataset:
Partita for panpipe and orchestra by Boris Dubosarsky: between baroque and contemporaneity
Authors: BEREZOVICOVA Tatiana
Published: January 2023

Th e study is dedicated to a large-scale work by the famous composer Boris Dubosarschi (1947—2017). Written in 2004, the Partita for panpipe and orchestra has not yet been studied by musicologists, although it deserves it for a few reasons. It is a multifaceted work, merging the peculiarities of several types of instrumental cycle: baroque suite, baroque sonata, modern suite, symphony, concerto. Framed generally in the stylistics of pre-classical music, the Partita also reveals some features of contemporary writing. A special quality is given by the combination of panpipe and chamber orchestra sonority. The original concept, the attractive musical language, the solo panpipe full of virtuosity and melody — thanks to these qualities the work is in demand in artistic and pedagogical practice, being intended for professional performers and students from the higher level of musical studies. The article is a tribute to the memory of Boris Dubosarschi who would have turned 75 in 2022.
Televisual mediating communication
Authors: STEPANOV Georgeta
Published: January 2023

Th e mass media’s socialization discourse includes a varied range of journalistic activities, including journalistic mediation. Journalistic mediation is a voluntary process that ensures the formation of fl exible frameworks for exposing and debating social problems and confl icts. Th is type of media activity is most oft en carried out through television journalism. Th e purpose of the research carried out in this study resides in the conceptualization of the televisual mediating communication and in projection of its identity profi le in the contemporary media context. In order to achieve this prerequisite, the investigative eff ort has been oriented to explain the essence of mediating journalistic activity, in general, and the television mediating communication in particular, as well as its peculiarity by describing the main signs, characteristics, missions, etc. Th e case study was based on the talk-shows Vorbește Moldova and Время правды (Timpul adevărului) from the Prime TV channel.
A Synthesis and Review of Ethnomedicinal Uses, Phytochemistry and Biological Activities of Paropsia brazzeana Baill. (Passifloraceae)
Authors: Maroyi Alfred
Published: January 2023

Paropsia brazzeana is a shrub used traditionally to treat various human diseases and ailments. Paropsia brazzeana naturally occurs from Cameroon and the Central African Republic south to Angola, the Caprivi strip of Namibia, Botswana and Zimbabwe. The aim of this review was to provide an overview and critically analyze the ethnomedical uses, phytochemistry and biological activities of P. brazzeana. The results of the current study are based on literature survey conducted using various search engines such as Elsevier, Pubmed, Google scholar, Springer, Science Direct, Taylor and Francis, and pre-electronic sources such as books, book chapters, scientific journals and other grey literature. The fruit, leaf, leaf sap, root, root bark and stem bark decoction or infusion of P. brazzeana are mainly used as charm and rituals, and traditional medicine for gastro-intestinal infections, gonorrhoea, malaria and toothache. Chemical constituents identified from P. brazzeana include alkaloids, hydrocyanic acid, polyphenol, proanthocyanidins, reducing sugars, saponins, steroids, tannins and terpenes. The species possesses biological activities such as antiamoebic, antibacterial and antispasmodic activities. Paropsia brazzeana is a valuable medicinal plant species and future research should focus on animal experiments aimed at assessing toxicity and clinical efficacy of species extracts.
Anti-Post-Traumatic stress Potential of Strawberry (Fragaria) and Carissa carandas Leaves: A Review
Authors: Arun Kumawat Jaymala , Shrivastava Birendra , M. Mute Vaishali
Published: January 2023

Post-traumatic stress disorder (PTSD) is the least apperceived mental disorder globally, associated with trauma and stressor cognate disorder. Administration of synthetic drugs on a constant schedule may lead to adverse events and other complications. Thus, Anti-PTSD medications require novel herbal pharmacological therapy. Recently, Anti-PTSD activity of Carissa carandas (CC) and Fragaria leaves (FL) has been demonstrated. Both are valuable bioresource for a range of health-related applications since they accommodate as a source of bioactive compounds with powerful antioxidant potential higher than in other berries. They possess faculty to cross the blood-brain barrier and chelate transition metal ions as well as forage pathological amounts of reactive oxygen and nitrogen species. For neuro-pathophysiology and pharmacological evaluations, pharmacologically different animal models of PTSD have been developed. Animal models are a prominent approach to learn PTSD without requiring to use of actual victims. A genuine effort has been taken in this article which provides the clear and cosine worldwide proven anti-PTSD potential of CC and Fl. The objective behind this article is to new vision to present and future scientists, researchers, industries, and regulatory bodies on the potential anti-PTSD potential of CC and Fl for the betterment of society by highlighting clinical and pre-clinical studies which contributed to support the concept. Any outcome in a model can be extrapolated to humans, giving scientists a better picture of what to anticipate mechanistically and in treatment response. Thus, CC and FL have wide application in mental disorders precisely in PTSD and as being herbal formulation, it has lesser adverse effects as compared to synthetic drugs.
Current concepts of Drug Therapy in Dentistry: A Review
Authors: Gupta Ravi , Satpathy Soumyadev , Kumar Hemanth , Kamath Vignesh , Pandey Lakshmi , Dubey Rashi
Published: January 2023

Knowledge and awareness about current concept of drug therapy in dentistry is very important for clinicians to deliver a high quality of care to their patients. Most of the patients report to dental setup with the chief complaint of pain and swelling. Efficient utilization of latest regimen of analgesics and antibiotics not only helps in reducing pain and swelling but also build up good trust with the dentist. In the present time numerous newer analgesics like ketorolac and tramadol are available in the market. This review article gives an overview of newer analgesics, antibiotics, local anesthetic agents, and delivery devices which will enable the dentist to provide Painless Dentistry.
Utilizing Canva Application Training to Improve Skills and Product Sales in Micro Small Medium Enterprises (MSMEs) East Java
Authors: Sunarto Sofyanto Tri , Setiadi Pompong B.
Published: January 2023

Micro, Small and Medium Enterprises (MSMEs) are economic businesses in the field of sales or trade that are managed by individuals or business entities. The existence of MSMEs in the technological era needs to utilize applications that can support sales. Canva is a design app that can be used to support sales. Canva's role in Micro, Small and Medium Enterprises (MSMEs) is expected to be an application that makes it easier for actors to market their selling products. This study aims to determine the effect of Canva training on improving the skills and sales of Micro, Small and Medium Enterprises (MSMEs). The approach method used in the implementation of this training activity includes monological and dialogic methods. Based on the results of the study, training on using the Canva application to increase sales and skills has a positive effect on MSME owners. This is due to the use of the Canva application which is easily understood by all people and the costs incurred are not much.
The The Role of Firm Size in Moderating the Relationship Between Profitability and Share Prices of Food and Beverage Companies
Authors: Akbar Taufiq
Published: January 2023

Firm size is still an interesting topic regarding its role in moderating factors that affect share prices. Therefore, the goal of this study is to determine how firm size affects the relationship of profitability, as measured by Gross Profit Margin (GPM), Operating Profit Margin (OPM), and Net Profit Margin (NPM), on share prices of manufacturing companies in the food and beverage sector from 2016 to 2019. Based on the purposive sample technique, 40 observations from 10 companies were chosen. AMOS 24 software was used to do the investigation using the structural equation modeling (SEM) method. In the initial model, it is clear from this analysis that OPM and Company Size significantly affected stock prices. At the same time, there is no significant effect of GPM and NPM on share prices. The second model demonstrates that firm size can moderate the relationship between GPM and OPM on share prices. However, this study cannot prove that firm size can moderate the effect of NPM on share prices.
Fourteen Years of Sustainability Reporting Research in Accounting: Bibliographic Studies
Authors: SURURI Rizky Yuniar , Aryani Y. Anni , Gantyowati Evi
Published: January 2023

Some companies that still apply the single-profit paradigm cause environmental damage, so there is a need for accountability to stakeholder through media sustainability reports. This study aimed to provide an overview of the development of sustainability reporting research for 14 years in Indonesia. Charting the field and analyzing community approach were used in this research. A research sample consisting of 50 articles obtained from 21 journals accredited Sinta 2 from 2009 to January 2022. The results indicated that the most widely used research method is the analytical method and the articles that received the most citations were published in 2015. In addition, this study also found that there are still research variables that are inconsistent with sustainability reporting, namely antecedent variables in the form of audit committees and consequence variables in the form of financial performance. Therefore, it is necessary to conduct an in-depth study to determine the cause of the inconsistency of these variables.
Effect of External Audit Opinions and Audit Committees on Financial Resource Management in Public Sector Entities
Authors: Mwombeki Frank
Published: January 2023

External audit opinions (EAO) and Audit committees (AC) have been studied in different contexts, yet the link between them and the management of financial resources, especially in government entities in Tanzania, has empirically not been captured. This paper examined the influence of EAO and AC on managing financial resources taking Tanzania government entities as a reference. It uses resources dependency theory to explain the main topic. Data were collected on 230 government entities from Controller and Auditor General (CAG) reports and audited financial statements for 2014/15 to 2019/20. Descriptive statistics and the Fixed effect technique were used to analyze data. The results show that unqualified audit opinion occurred most among public entities. Specifically, the qualified audit opinion occurred most in LGAs. Also, a significant frequency of AC weaknesses appeared in LGAs and Public BICA.Moreover, the estimation results show that audit report positively and significantly influences financial resource management (FRM), whereas AC weakness has a negative relationship with FRM. Therefore, the President’s office and the Parliament should emphasize the management of resources strategies in public entities, especially LGAs. This paper will add knowledge on EAO and AC as tools for financial resources management in government entities.
Psychosocial Life Aspects among Substance Misuse Clients who are at Rehabilitation Phase: A Narrative Review
Authors: Alsubaie Salman
Published: January 2023

Objective

The present study aimed at exploring the psychosocial life aspects among substance misuse clients through conducting a review of the literature related to the research topic. A scoping search in the literature revealed the significant lack of both local, regional and international studies exploring the psychosocial life aspects among substance misuse clients who are at the rehabilitation stage.

Method

A comprehensive literature search was performed using the keywords: “psychosocial, “psychological”, “social”, “life”, “rehabilitation” and “substance misuse”. The search process was performed in the following electronic databases “MEDLINE, PubMed, CINAHL, PsycINFO”. Full text articles, published in English during the period between 2016 and 2021 were included in the literature.

Results

A total of 7 studies were found to be in relation with the topic addressed in this study, which is the psychosocial life aspects of substance misuse clients at rehabilitation phase. The results showed that there is a significant weakness of psychosocial life aspects among substance misuse clients, in addition to a significant lack of both educational and training program that aim at enhancing and improving the psychosocial life aspects among substance misuse clients who are at the rehabilitation phase.

Conclusion

The study concluded that there should be concise and clear measurement tools to be used in assessing the psychosocial life aspects of substance misuse clients who are the rehabilitation phase.
Pseudogout After Total Knee Arthroplasty Meeting Minor Criteria for Infection Treated by Polyethylene Exchange
Authors: Cole Matthew , Patel Akshar , Collins Lacee , Hawkins Barrett , Sherman William F
Published: January 2023

Case

Pseudogout in a total joint arthroplasty is rare and can be difficult to distinguish from a prosthetic joint infection (PJI). In this unique case, we present a patient who developed her first episode of pseudogout 17 years after her primary total knee arthroplasty at age 75.

Conclusion

With similar clinical and laboratory findings, it is important to distinguish the presence of PJI and inflammatory arthropathy. The use of diagnostic tools available, consideration of patient co-morbidities, and timing of symptoms can help guide surgeons’ treatment.
Open Access Research Journal of multidisciplinary studies: An analysis
Authors: Anjali Sandesh Kale
Published: January 2023

Open access research journal is the important medium utilized by the research scholars to publish their research work. Open Access Research Journal of Multidisciplinary Studies is one such journal which helps the researcher from different disciplines to publish their research work. The purpose of the study is to analyze type of research, authorship pattern, length of articles, contributing institutions etc. which are contributing their research in Open Access Research Journal of Multidisciplinary Studies. Content analysis research method was employed to study the contents of the journal. Sample for the study was articles published in the journal from the period of 2021-2022. Analysis of the articles revealed that, majority of the articles published in the journal are research and review articles. The most prolific country contributing their research was India and Nigeria. The majority research articles published in the journal were in the page range of 1 to 10 pages.
Public health information needs of urban residents: An opportunity to promote pharmacists role in community health
Authors: Paul Otor Onah  , Aliyu Kaigama  , Catherine Chioma Idoko
Published: January 2023

Health information is a foundational component of public healthcare education that is intended to promote individual and community health, prevent diseases and optimize treatment outcomes for patients. Generally, health information assist people make healthcare decisions, adjust lifestyle and promote self-care. Health information needs within the community is less well studies in Nigeria, so this study aims to explore the needs for health information within an urban community. This was a cross sectional questionnaire based survey study among randomly selected adults (≥ 18 years). Data was analyzed using descriptive statistics as well as Chi square to determine association between demographic variables and health information needs. P values ≤ 0.05 was considered statistically significant. The results showed that about half of respondents expressed their need for information related to sexual/reproductive health, childhood diseases, vaccination, identification of disease symptoms and how to participate in the medical decision making process. There was significant association between demographic variables and the need for health information. There was diversity of health information needs which reflected the desire to participate in many aspects of healthcare through access to relevant and accurate information. This will provide opportunity for pharmacists to deepen their involvement in providing health information in the course of pharmaceutical care services. Health information needs of the community was largely unmet by the cadre of health workers providing them. It’s therefore important that Pharmacists at the community level step up to fill this huge information gap as part of value added services to the public
Comparison of Normal Vaginal Delivery with or without Antenatal Exercise in Primigravida Presenting in A Tertiary Care Hospital
Authors: Ashraf Faisal , Kanwal Rehana , Inam Iram , Kanwal Memuna , Mahreen Mizrah , Rehman Tanzeela
Published: January 2023

Objective: To compare the frequency of normal vaginal delivery in primigravida females with or without antenatal exercise Study design: Randomized Controlled Trial Study Duration: 6 months i.e. 4-5-2021 to 4-11-2021 Setting: Department of Obstetrics & Gynecology, Jinnah hospital, Lahore. Material and methods: 100 females fulfilled the criteria were enrolled. Then females were randomly divided in two groups. In group A, females were advised to do exercise daily. In group B, females were not advised to do any exercise. Then females were followed-up till delivery. Mode of delivery was noted. All this information was collected on proforma. Data was analyzed in SPSS. The study groups were compared by applying chi-square test. P-value ≤ 0.05 was considered as significant. Results: In exercise group, the mean age of patients was 26.00±4.76years. In no exercise group, the mean age of patients was 26.32±4.97years. In exercise group, normal vaginal delivery occurred in 42 (84%) patients. In no exercise group, normal vaginal delivery occurred in 29 (58%) patients. The difference was significant (p<0.05). Conclusion: Thus with exercise, then chances of normal vaginal delivery increase significantly in primigravida. Keywords: Normal vaginal delivery, antenatal exercise, primigravida
Relationship Between Liver Function Tests & Cardiovascular Risk Factors in Stage 3-5 Pre-Dialysis Chronic Kidney Disease
Authors: Shehzad Khalid , Rehman Obaid Ur , Khan Aurangzaib , Khattak Munaza , Ahmed Siyab , Shehzad Khalid , Orakzai Shabir Ahmed
Published: January 2023

Objectives: The main objective of this study was to evaluate the relation between liver function tests and biochemical cardiovascular risk factors in chronic kidney disease patients. Methodology: this study was conducted in Khyber Teaching Hospital Peshawar, from Ist May 2022 till 31st Oct, 2022. 250 patients in total were included in this study. All the people included in this study were chronic kidney disease patients at pre dialysis stage 3 to 5. Data collected included demographic information, liver function tests and biochemical cardiovascular risk factors. CKD-EPI equation was used to calculate glomerular filtration rate. Results: This study resulted in ALT being negatively correlated with C reactive protein and intact level of parathyroid hormone and positively correlated with glomerular filtration rate, triglyceride, calcifediol and albumin. Gamma-glutamyl transferase was negatively correlated with HDL cholesterol and positively correlated with glomerular filtration rate, triglycerides and C reactive protein. AST was negatively correlated with C reactive protein and intact level of parathyroid hormone and positively correlated with glomerular filtration rate, HDL cholesterol, albumin and calcifediol. In diabetic patients AST and ALT were positively correlated with glomerular filtration rate, additionally AST was also positively correlated with HDL cholesterol but negatively with intact parathyroid hormone. Gamma-glutamyl transferase had no correlation. In total population of the study and in diabetic group correlation analysis was run between glomerular filtration rate and biochemical cardiovascular risk factors, it resulted in GFR being negatively correlated with albuminuria, C reactive protein and intact parathyroid hormone and positively correlated with triglyceride, calcifediol and albumin. A partial correlation analysis, controlled for GFR, was also run between cardiovascular risk factors and LFTs. It resulted in no correlation between both. Practical implication: this study could be useful when planning the treatment of CKD patients with cardiovascular risk factors. Also in predicting the risk of cardiovascular disease in CKD patients based on the LFTs. It could also help initiate further reseach on related topics like the role of LFTs in predicting cardiovascular disease in CKD patients. Conclusion: this study concluded that relation between liver function tests and biochemical cardiovascular risk factors in chronic kidney disease patients could be the function of compromised glomerular filtration rate. Keywords: cardiovascular risk factors, chronic kidney disease, aspartate transaminase, gamma-glutamyl transferase, alanine transaminase
Frequency of Perineal Trauma in Women Undergoing Spontaneous vs Directed Valsalva Type Pushing in Labour
Authors: Ayub Fatima , Mustafa Nilofar , Aslam Pakeeza , Kanwal Rehana , Mushtaq Qurutulain , Tufail Shazia
Published: January 2023

Objective: To compare the frequency of perineal trauma in women undergoing the spontaneous vs the Valsalva-type pushing in the second stage of labour. Study Design: Randomized controlled trial Duration of Study with Dates: The study was carried out from 15-12-2020 to 19-03-2021. Setting: Department of Obstetrics and Gynaecology, Combined Military Hospital, Lahore.National University of Medical Sciences NUMS. Material and Methods: A total of 154 labouring females were enrolled in the study. These females were randomly assigned to one of two groups, A (the Valsava-type pushing method group) and B (the spontaneous pushing group). After the delivery of the placenta, the patients were all examined for any perineal trauma as per the operational definition. Results: Patients ranged between 18-40 years of age with a mean age of 26.3±4.0 years in Group A and 27.0±3.3 years in Group B. All the patients were between 38-40 weeks of gestation at the time of enrollment with mean gestational age being 39±0.7 weeks for group A and 38.9±0.7 for group B. There were 61 primigravida (39.6%, 34 in Group A and 27 in Group B) and 93 multigravida (60.4%, 43 in Group A and 50 in Group B). All women delivered vaginally in the cephalic presentation. The mean length of the second stage of labor was 25.7±29.0 min for the Valsalva pushing group and 31.6±37.5 min for the spontaneous pushing group. The mean fetal weight was 3.1±0.3 kg for both groups. 43 (55.8%) patients in the Valsalva pushing group and 46 (59.7%) in the spontaneous pushing group underwent an episiotomy during delivery. 9 (11.7%) patients in each group sustained perineal trauma (x2 = 0.0, p = 1.0). No one in the sample suffered greater than a second degree laceration. Out of the nine patients that did incur perineal trauma in the Valsalva type pushing group, 4 (44.4%) were first degree perineal tears and 5 (55.6%) were second degree perineal tears while among those in the spontaneous pushing group, 2 (22.3%) fell in the first degree tear category and 7 (77.7%) in the second degree tear category (x2 = 1.0, p = 0.317). Conclusion: Our findings suggest that there is no association between the rate of perineal trauma among patients who underwent the directed Valsalva- type method of pushing and those that employed the spontaneous pushing method during the second stage of labour. Keywords: Perineal trauma, Perineal tears, Second stage of labour, Pushing methods in labour, Valsalva- type pushing, Directed pushing, Spontaneous pushing
Predictors for Disease Severity in Covid-19
Authors: Gul Rida , Gul Ayesha , Gul Rida , Khan Hamza Sattar , Haroon Muhammad , Khan Dawood , Khan Asghar
Published: January 2023

Background: Coronavirus disease 2019 affects millions of people to date. Age, comorbidities, fever, shortness of breath, and different Laboratory parameters like serum forum, C- reactive protein, and lactate dehydrogenase level are the important predictors for the severity of the disease. Material and methods: This case-control type study was conducted in April to June2021 in Khyber Teaching Hospital Peshawar. PCR-detected coronavirus disease 2019 patients were assessed. These patients were divided into four groups based on presenting symptoms, image findings for pneumonia, oxygen saturation, and ventilatory support. These groups were compared for different parameters, including the presenting symptoms and laboratory parameters. Results: Out of 140 patients, 54.3% were males. There was a statistically significant difference (p< 0.05) in presenting complaints like fever, shortness of breath, body aches, loss of taste, anorexia, and laboratory parameters like serum ferritin, total leucocyte count, lactate dehydrogenase, C-reactive proteins, and d-dimers in these groups based on the severity of the disease. These parameters were independent predictors for disease severity in Coronavirus disease 2019. Further studies are recommended with a large sample size for more evaluation of these associations. Practical Implication: This study will be helpful in determing the disease severity prediction in patients suffering from COVID-19. For community benefit, this study will be important as it helps the people to determine either they are sufferimg from COVID-19 or not. It will also help them to take the necessary precautionary measures. Conclusion: The study concluded that there are several clinical predictors of COVID -19 like fever, old age anorexia, loss of taste, shortness of breath, and muscle aches. In addition, some laboratory markers such as serum ferritin, CRP level, total leucocyte count, and LDH are responsible for indicating the disease severity. Earlier disease prediction results in timely and early intervention, thereby helps in the prevention of progression toward critical stage. Keywords: Coronavirus disease 2019 (COVID-19), disease severity, mild and moderate disease, severe and critical disease
Characteristics and Outcomes of Community Acquired Versus Hospital Acquired Sepsis at A Tertiary Care Hospital, Karachi
Authors: Shah Rabeea , Salahuddin Naseem , Khan Shameem Behram , Masroor Rabiah , Abbas Kiran
Published: January 2023

Objective: The study compared the demographics, clinical characteristics and site of infection leading to community acquired and hospital acquired sepsis. Secondly, the study further compared the distribution of the isolated organisms and complications caused by community and hospital acquired sepsis. Methods: A prospective cohort study was undertaken at the intensive care unit, high dependency unit, and critical care unit at the Indus Hospital, Karachi, Pakistan between 14-April-2021 to 15th-April-2022. All the individuals diagnosed with sepsis, admitted through the Emergency Department or transferred from a ward were included in the study. Age < 15 years or who were shifted from another hospital were removed from the study. The data on demographics, vital signs, SOFA score, site of infection, laboratory parameters, radiological investigations, culture results, and complications, if any, were filled on a pre- designed Performa. Results: Age of the participants was 42.1 ± 17.4 years with a predominance towards female gender. Urinary tract was the most common site from which the organisms were isolated with a frequency of 35 (28.9%). Table 3 revealed that gender was significantly associated with gender (p=0.008). It was found that the majority of the community acquired sepsis were reported in males while the majority of the hospital acquired sepsis was reported in females. Furthermore, marital status (p=0.019) and site of infection were significantly correlated with the hospital acquired sepsis. It was further found that mean creatinine was significantly lower in community acquired sepsis than those with hospital acquired sepsis [(7.83 ± 4.85) vs (15.4 ± 10.4); p<0.001]. Conclusion: The study revealed both hospital acquired and community acquired sepsis are life threatening conditions that may add significant burden on the healthcare facility while at the same time placing significant financial burden upon the patients. Keywords: Sepsis; Community-acquired infections; Nosocomial; Mortality
Prevalence of Periodontal Disease and Caries Associated with Erupted Third Mandibular Molar
Authors: Javed Farhan , Shafi Nighat , Awais Tabassum , Virda Maryam , Maryam Madiha , Chaudhry Sana , Zafar Sadia
Published: January 2023

Aim: To assess the prevalence of periodontal disease and caries on 2nd mandibular molar in association with erupted 3rd molars. Methodology:: This cross sectional study was conducted at the Periodontology Department, Avicenna dental college, Lahore from July 2021 to June 2022. A total of 81 patients were examined in the age range of 21-50 years. Patients of both genders were assessed. Data was entered and analysed by IBM SPSS 25. Level of significance was kept at p-value ≤ 0.05 Results: Total of 81 patients were examined with the total number of teeth evaluated were 156. Age taken as demographic variable was further divided into three groups. Group 1 consisted of patients between the age range of 21-30 years n=18 (22.22%). Group 2 have patients between the age range of 31-40 years n=43 (53.09%) and Group 3 consisted of age range of 41-50 years patients n=20 (24.69%).Highest prevalence of distal caries was related to level A (68.33%) and periodontal disease was prevalent in level C followed by level B molars Conclusion: Regardless of eruption status, 3rd molar is associated with occurrence of periodontal disease and caries on 2nd mandibular molars. Ergo, regular clinical evaluations and monitoring are required even in apparently symptom free 3rd mandibular molars, as their existence is analogous to Distal Surface Caries (DSC) and PPD≥5mm development in mandibular 2nd molars. Else, to improve the long term survival of 2nd mandibular molars, prophylactic extraction of 3rd mandibular molars can be considered as a treatment option. Keywords: Eruption status, distal surface caries, periodontal disease.
Frequency and Clinical Outcomes of Women with Postpartum Hemorrhage at a Tertiary Care Hospital
Authors: Ramejo Bushra Begum , Ramejo Mubashir Ahmed , Soomro Sanober , Tunio Mehtab Ali , Ramejo Musharraf Ahmed
Published: January 2023

Background and aim: Postpartum hemorrhage (PPH) is still a leading cause of maternal morbidity and mortality globally. Postpartum hemorrhage is characterized as excessive bleeding (> 500 ml) from the vaginal tract following childbirth. The present study aimed to determine the frequency and clinical outcomes of women with postpartum hemorrhage. Materials and Methods: This cross-sectional study was conducted on 1346 patients who underwent vaginal delivery in the department of obstetrics and gynecology, Kausar Hospital, Khairpur Mirs from March 2021 to March 2022. The study included all the women who had postpartum hemorrhage following vaginal birth in the labor room or who were referred with primary postpartum hemorrhage. Patients with prior history of bleeding disorders and on warfarin were excluded from the study. SPSS version 26 was used for data analysis. Results: Of the total 1346 patients, the prevalence of postpartum hemorrhage was 12.6% (n=170). Out of 170 PPH cases, the incidence of primary and secondary PPH was 138 (81.2%) and 32 (18.8%) respectively. The age-wise distribution of patients were as follows: 26 (15.3%) had <20 years, 62 (36.4%) in 21-30 years, 68 (40.1%) in 31-40 years, and 14 (8.2%) in >40 years. The incidence of primiparas, multipara, and grand multipara were 34 (20%), 58 (34.1%), and 78 (45.9%) respectively. The booked and unbooked patients were 56 (32.9%) and 114 (67.1%) respectively. Among 170 PPH patients, the incidence of spontaneous vaginal delivery, instrumental delivery, and cesarean section were 52 (30.6%), 56 (32.9%), and 62 (36.5%) respectively. The major causes of PPH was uterine atony, perineal and vaginal tears, and prolong labor found in 112 (65.9%), 56 (32.9%), and 38 (22.4%) respectively. Conclusion: The present study concluded that the prevalence of PPH was 12.6% among total cases. Primary PPH was more prevalent than secondary PPH and uterine atony was the most common cause followed by perineal and vaginal tears and prolong labor. Additionally, unbooked patients were more susceptible to PPH. Risk factors assessment, unnecessary induction, and third stage labor active management can prevent the PPH. Keywords: Postpartum hemorrhage, Clinical outcomes, Uterine atony
Symptoms and Severity of Depression in Copd Patients
Authors: Usman Abid , Shah Zahoor Ahmed , . Saifullah , . Lalchand , Awan Inayatullah , Khan Muhammad Firaz
Published: January 2023

Objective: The purpose of this research was to identify how often individuals with COPD suffer from depression and what variables may be contributing to their feelings of depression. Study Design: Cross-sectional study Place and Duration: This cross-sectional study was conducted at Department of Psychiatry, Lady Reading Hospital, Peshawar in the period from April, 2022 to September, 2022. Methods: Total 220 patients of both genders had age 20-85 years were included in this study. All the patients had chronic obstructive airway disease were presented. Patients' full demographic information, including age, sex, BMI, job status, and smoking history, was collected after obtaining informed written consent. Association of depression and its severity were recorded among all cases. We used SPSS 24.0 to analyze all data. Results: One hundred and forty (63.6%) cases were males and eighty (36.4%) were females. Patients mean age was 61.03 ±7.48 years and had mean BMI 25.6±7.26 kg/m2. Majority 150 (68.2%) cases were unemployed. 135 (61.4%) cases were smokers. We found a high frequency of depression in 130 (59.1%) patients in which 60 cases were had severe depression. Older age, living alone and unemployment were the risk factors of depression among COPD patients. Conclusion: We concluded in this study that frequency of depression among COPD patients were high found in 59.1%. Depressive symptoms were shown to be associated with several different risk factors in COPD patients. Older COPD patients, men, those who are retired or jobless, and those who do not have a significant other are at a higher risk of depression. Keywords: COPD, Depression, Old age, Severity
An Evaluation of the Role of the Radiologist and Surgeon in the Management of Hepatic Trauma at Qazi Hussain Ahmad Hospital, Nowshera, kpk
Authors: Ahmad Kamran , Habib Erum , Zahir Zarlakhtha , Habib Humera , Khattak Rashda
Published: January 2023

Aim: This study aims to compare the surgical results and CT scan findings in patients with hepatic trauma to evaluate the sensitivity and usefulness of sonographic data. Study Design: A Single-center study. Study duration : From Jan 2020 to Feb 2021, the Radiology and Surgery Divisions at Qazi Hussain Ahmad Hospital in Nowshera. Methods: There will be a retrospective chart review of all patients suspected of having sustained hepatic injuries admitted to the surgical department From Jan 2020 to Feb 2021 and subsequently present to the department of Radiology. There were two groups of patients: Group I, who had surgical intervention, and Group II, who were hospitalized and treated non-operatively. Prospective cohort research in which the sonographer and clinicians who analyzed emergency sonograms compiled data from all patients. Patients injured in their livers within this time frame were tracked down. Results: Overall, 291 patients (72% of the sample) were included in the study, with 83 patients (29% of the sample) requiring surgical intervention and 208 patients (71% of the model) being handled conservatively. All Group-06 patients had CT scans. Of the 83 patients who had surgery, 11 were classified as having a Grade-1 complication, 12 as having a Grade-11 difficulty, 44 as having a Grade-Ill complication, 18 as having a Grade-IV complication, and three as having a Grade-V complication. In a study with 208 patients who did not have surgery, 15 (73%) had a Grade-I fall, and 56(28%) experienced a Grade-11 fall. Sonographic data and surgical results in individuals who have had surgery, and how they compare and contrast. Cconclusion: Ultrasonography is the most sensitive method for determining the severity of liver damage caused by forceful abdominal trauma. Since it may be done at the bedside and repeated as needed, it serves as a primary diagnostic strategy in these patients and helps when paracentesis is necessary. Keywords: Abdominal injury, Shortened Surgical Terminology for Liver Trauma (AST), liver trauma grades, CT scan, bleed, liver injury,
Investigation of Microvascular Complications of Type-2 Diabetes Mellitus Patients and its Clinical Outcome
Authors: Shehzad Shahid , Khan Muhammad Zubair , Chandio MS. Khushboo , Zafar Hamid , Munawar Rana Zohaib , . Asif
Published: January 2023

Background: Diabetes mellitus type 2 is recognized as a global pandemic due to its substantially increasing prevalence. This metabolic disorder bears a significant potential incidence of microvascular complications (MVC) in chronic patients including neuropathy, retinopathy, and nephropathy which may prove fatal. Objectives: The study aimed to investigate the incidence of microvascular complications, its associated risk factors and comorbidities in the chronic diabetic population. Methods: This cohort was executed to assess the clinical records of visiting diabetic patients presented at PIMS hospital, Islamabad from July 2020 to June 2022. A total of 630 patients with T2DM of different age and sex groups, were included in the study and their clinical outcomes of MVCs were analyzed. Results: The overall incidence of MVCs was found 43.49% significantly (p<0.05) affecting the aged population with prolonged ailment, raised HbA1C of more than 8.5, raised BMI, hypertensive and genetically predisposed patients. The incidence was found high in females, aged population (more than 60 years), married, unemployed, urban population and the prolonged illness, overweight, hypertensive and genetically predisposed people with a family history had the highest incidence of MVC (p<0.05). Among the MVCs, the patients highly suffered (p<0.05) from neuropathy, followed by retinopathy and nephropathy due to persistent ailment of T2DM, hauled glycated hemoglobin, overweight and hypertensive population. Practical implication: This study paved the way for clinicians to instigate diabetic patients MVCs of neuropathy, retinopathy and nephropathy for the sake of health of patients and avoid such complications by screening out the associated risk factors and comorbidities Conclusion: Hence, it was concluded that microvascular complications were the major clinical outcome in T2DM patients. Therefore, managemental and preventive therapies at the earliest stage may delay the progression of MVCs in them and will revive their quality of life. Keywords: Glycated hemoglobin; Hypertension; Nephropathy; Neuropathy; Obesity; Retinopathy.
Prostatic Inflammation's Effects on Individuals with Benign Prostate Hyperplasia's Clinical Consequences
Authors: Shahzad Iqbal , Yousuf Muhammad Ali , Hussain Khadim , Manzoor Mumtaz , Pathan Ghulam Mustafa , Ahmed Tanveer
Published: January 2023

Objective: In order to ascertain the impact of silent inflammatory prostatitis on the clinical results of individuals receiving trans urethral prostate resection owing to benign prostatic hyperplasia. Study Design: Retrospective study Place and Duration: This retrospective study was conducted at Liaquat National Hospital Karachi in the period from April, 2022 to September, 2022. Methods: Total 330 patients were presented in this study. In this study, individuals over 45 years without a history of urologic surgery who presented to a urology clinic with lower urinary tract symptoms related to benign prostatic hyperplasia were included. Pathological outcomes and clinical indicators were evaluated before and one year after surgery. Mean Standard deviation was used to present data and categorical variables were assessed by frequencies and percentages. Results: Mean age of the patients was 61.3±10.42 years. Among 330 cases, 200 (60.6%) patients were had benign prostatic hyperplasia and 130 (39.4%) cases had both prostatic inflammation (category-IV) and benign prostatic hyperplasia. Before TURP, mean prostate volume in BP patients was 55.7±8.11 m3 and in BPH/PI patients was 55.3±10.6 m3 and after TURP mean prostate volume in BP patients was 23.2±1.20 m3 and in BPH/PI group 23.4±8.17 m3. We found that people with prostate inflammation had lower Qmax values and a higher preoperative prostate score compared to those who had no signs of inflammation before to prostate transurethral resection. Conclusion: In this study, we came to the conclusion that in individuals with benign prostatic hyperplasia, prostate inflammation without symptoms might worsen lower urinary tract symptoms and the rate of urine flow. Keywords: Benign Prostatic Hyperplasia (BPH), Prostate Pathology, Prostatic Inflammation
Outcome of Combined Periodontal-Orthodontic Treatment of Pathologic Tooth Migration: A Longitudinal Study
Authors: Tariq Sahibzadi Fatima , Mehdi Mohammad Aun Ali , Zahra Shazmeen , Khan Taimur , Farid Hijab , Azeem Samir
Published: January 2023

Introduction: A number of periodontal bone abnormalities, most of which are horizontal, have been associated with flared and long incisors. Individuals with anterior incisor displacement and periodontal disease may benefit from orthodontic-periodontal therapy. Objective: To determine the outcome of combined periodontal-orthodontic treatment of pathologic tooth migration Study design: A longitudinal study Place and Duration: This study was conducted at Rehman college of dentistry Peshawar, Pakistan from February 2022 to July 2022 Methodology: A 4-person team designed the study's procedures. On 56 maxillary incisors with horizontal bone anomalies, this surgery was performed to remove circumferential supracrestal fibrotomy and orthodontic-periodontal therapy. To compensate for the angular bone shortage in front teeth treated with orthodontics, guided tissue regeneration and periodontal regenerative surgery were performed. Before, throughout, and six months after guided tissue regeneration treatment (T1), cone-beam computed tomography images were done (T2). At each of the first three time points, the depth of the probing pocket and the degree of clinical attachment loss were determined. Paired t-tests were used to analyse the data. Results: Clinical attachment loss decreased by 0.28 mm from T0 to T1 (P <0.05). The distance between the cementoenamel junction and the bone top decreased by 0.65 mm (P <0.05). Alveolar bone thickness decreased by 0.45 mm on both the lingual and labial sides of the bone (P<0.05). Bone anomalies in some teeth have been converted from horizontal to vertical. From T1 to T2, radiographic testing revealed a 2.16 mm vertical and 1.45 mm horizontal bone redeposition (P<0.05), as well as improvements in probing pocket depth and clinical attachment loss (P<0.05). During combination therapy, the cementoenamel distance decreased from 2.10 mm to 1.31 mm (P <0.05). Conclusion: We were able to address periodontal diseases caused by improper bone implantation by combining orthodontic and periodontal treatment. By altering the bone structure, it is possible to improve the outcome of directed tissue regeneration following orthodontic invasion with fibrotomy. Keywords: orthodontic and periodontal treatment, outcome, bone implantation, Periodontal disease
Prevalence and Pattern of Congenital Coronary Artery Anomalies in Patients Undergoing Coronary Angiography at a Tertiary Care Hospital
Authors: Latif Abdul , Khalil Muhammad Shahab Uddin , Ullah Sami , Parvez Muzdalfa , Shah Hamid Ali
Published: January 2023

Objective: This research aimed to characterize the clinical presentation, frequency, and distribution of CAAs in people experiencing angiography. In this study, we reviewed the presence of CAAs in 4072 patients. Study design: Cross-section study Study Setting: Current research was conducted at Department of interventional cardiology, MTI- Hayat Abad Medical Complex, Peshawar from Ist July 2021 to 30th June 2022. Methods: The current research analyzed data from 4072 angiograms performed. The medical record of the patients was used to recruit the CAAs patient’s profile. Angelini's categorization was used to categorise the coronary anomalies and two interventional cardiologists reviewed each coronary angiography separately, and in the event of a discrepancy, a senior cardiologist was contacted to achieve a consensus. GE 520 and GE 2100 were used for the coronary angiogram. Operators have the option of using either a radial or femoral incision. Results: Finding of the CAAs was found in 103 cases of CAAs (a prevalence of 2.5%). According to the data, the average age of the patients was 59.64±13.73. Of them, 89 (2.19%) individuals had anomalous coronary origin and/or course, 9 (0.2%) had intrinsic coronary arterial system abnormalities, 3 (0.07%) had anomalous coronary termination, and 2 (0.04%) had a single coronary artery. Overall, 36 individuals (0.44%) were found to have an aberrant right coronary artery (RCA), with the RCA emerging from the left coronary sinus; this was followed by 54 patients (1.3%) who lacked a left main trunk and instead had a distinct origin for the LAD and LCX. Practical implication: Our understanding of CAAs has considerably improved from the development of novel diagnostic techniques, although the majority of the data available today comes from case reports and small case series. Further research is needed to fill the knowledge gap regarding the clinical effects of CAAs and their prognosis because epidemiological data are taken from studies conducted in other countries. Conclusion: Overall, 2.5 percent of research participants had congenital coronary abnormalities. The highest prevalence was found in anomalies origin and course. This study's prevalence of CAAs was comparable to that of other research, although the distribution of abnormalities was a little bit different. Keywords: Congenital Coronary Artery Anomalies, Coronary Angiography, Prevalence, Pattern