bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategi Dinas Perikanan dalam Pengembangan Sentral UMKM Ikan Pindang Desa Brondong Kabupaten Lamongan
Authors: Syaroh Nurul Mey , Nawangsari Ertien Rining
Published: November 2023

This The purpose of this research is to describe the strategy of the Department of Fisheries in developing the central UMKM for boiled fish in Brondong Village, Lamongan Regency. In addition, this study aims to describe the successes and shortcomings of the Fisheries Service's strategy in developing boiled fish centers. This study used descriptive qualitative method. Researchers collected data, observations, interviews and documentation to obtain complete and detailed data. Subjects of this study were: (1)head of the Fisheries Service, (2) business development and quality development section, (3) actors and (4) buyers. The results of study using the SOAR model: 1)strengths aspect of pindang fish is that it is processed without using formalin, and the advantage is that pindangbrondong is fresh and tender when processed. 2)aspects of opportunities are carried out in terms of quality improvement, marketing, and branding. 3) aspect of aspiration conveyed by traders to Service regarding development, and traders conveying suggestions related to promotion. 4)aspect of result that is felt by traders is evidenced by increased income of traders, the PANDU SISKAMAYA and Pindang Hygienic innovations have been running smoothly, (UPI).
Nejroseti golovnogo mozga pri sochetanii hronicheskoj cerebral'noj ishemii i saharnogo diabeta 2-go tipa
Authors: Фокин В. Ф. , Пономарева Н. В. , Коновалов Р. Н. , Шабалина А. А. , Медведев Р. Б. , Лагода О. В. , Боравова А. И. , Кротенкова М. В. , Танашян М. М.
Published: November 2023

Hronicheskaya ishemiya golovnogo mozga (HIM), oslozhnennaya saharnym diabetom 2-go tipa (SD2), harakterizuetsya bolee tyazhelym techeniem, svyazannym s hronicheskoj giperglikemiej. Cel' raboty — issledovat' organizaciyu konnektivnosti nejrosetej mozga po dannym funkcional'noj magnitnorezonansnoj tomografii (fMRT) pokoya u pacientov s HIM, stradayushchih diabetom 2-go tipa, po sravneniyu s bol'nymi HIM bez diabeta. V issledovanii prinyali uchastie 257 pacientov: 81 muzhchina i 176 zhenshchin v vozraste 50–85 let s HIM, chast' iz kotoryh boleli SD2. Ocenivali metabolicheskie pokazateli, sostoyanie mozgovogo krovoobrashcheniya, a takzhe kognitivnye funkcii. S pomoshch'yu fMRT pokoya analizirovali konnektivnuyu organizaciyu nejrosetej mozga. U bol'nyh HIM s SD2 pokazateli konnektivnosti ryada nejrosetej mozga s uchetom popravki na mnozhestvennost' sravnenij FDR (False discovery rate) statisticheski dostoverno snizheny (p (FDR) < 0,05) po sravneniyu s bol'nymi HIM bez SD2. Eto konnektivnosti rechevoj nejroseti pravogo polushariya s paragippokampal'noj oblast'yu levogo polushariya i s uglovoj izvilinoj pravogo polushariya, kotoraya yavlyaetsya sostavnoj chast'yu seti passivnogo rezhima raboty mozga. Konnektivnost' perednej poyasnoj izviliny, vhodyashchej v salientnuyu nejroset', s verhnej visochnoj izvilinoj byla znachimo nizhe u bol'nyh HIM s SD2. Dostovernye izmeneniya zatragivayut i mozzhechkovye seti. V celom, razmer i normirovannaya intensivnost' bol'shinstva issledovannyh nejrosetej pokoya nizhe u bol'nyh HIM s diabetom.
Review Of Smart Environment Tourism Indicator Policies In The Development Of The Likupang Tourism Special Economic Zone
Authors: Warouw Felly Ferol , Rotty Viktory Nicodemus Joufree , Pusung Piet Hein , Giroth Lady Grace Jane
Published: November 2023

This research is to analyze the application of tourism smart environment policies in the development of the Likupang Tourism Special Economic Zone (SEZ) in North Sulawesi, Indonesia. The data publication policy is explained by using a qualitative approach method. Assessment based on scores based on tourism smart environment indicators. The results of the study show that the tourism potential in the Likupang area is the government's policy by proposing this area as a tourism special economic zone. The policy was published in the form of Government Regulation number 84 of 2019 as a Legal Basis with an area of 197.4. The first question which describes the findings of the literature carried out in journal articles shows that the vision of a smart environment tourism policy in the development of the Likupang Tourism Special Economic Zone in the era of the COVID-19 pandemic has been carried out a lot. The second question is the researcher's attempts to trace the perception of stakeholders to the understanding of stakeholders about whether or not it is necessary to develop a smart environment in the Likupang SEZ area using a smart environment tourism approach at an ecocentrism or supportive level. The third question can be seen from the process of implementing the Likupang SEZ which is the government's effort to develop regional tourism potential, of course with a smart environment tourism approach as well as a way to reduce emissions, manage waste and involve community participation.
Countering Democratic Disruption Amid The Disinformation Phenomenon Through Artificial Intelligence (AI) In Public Sector
Authors: Mega R.A. Yashinta Sekarwangi
Published: November 2023

In today’s era, artificial intelligence (AI) has emerged as a groundbreaking technology that plays a vital role in shaping societies and revolutionizing various sectors. Many democratic countries are currently exposed to a variety of false information spread through social media. In politics, disinformation is often associated with the efforts of a particular movement or party to mobilize supporters against the moral order. The spread of disinformation causes the emergence of legitimacy problems in many democratic countries.   Citizen confidence in the credibility of official information in the news started to decline and shifts to alternative sources of information such as social media. Several countries that adhere to a democratic system make various efforts to fight the phenomenon of disinformation. The origins of the problems research want to examine the use of AI technology as an effort to overcome the spread of disinformation on social media. Furthermore, this research examines the challenges posed by AI disinformation and highlights several measures that democratic governments should adopt to mitigate its impacts. In summary, prioritizing the fight against disinformation in democratic countries is imperative to safeguard the integrity of democratic processes, enhance societal resilience, and foster an informed citizenry capable of making critical decisions for the collective benefit of the nation.
Review Pembuatan kokristalFarmasi Dengan Metode Mekanokimia
Authors: Yenti Revi , Zulhadjri Zulhadjri , Efdi Mai , Zaini Erizal
Published: November 2023

Pengembangan bahan aktif farmasi saat ini cukup pesat, salah satunya adalah pengembangan kokristal. Kokristal dibuat dengan menggabungkan antara bahan aktif farmasi dan koformernya dengan berbagai metode misalnya pelarutan dan penggilingan. Mekanokimia adalah metode yang efektif untuk persiapan sistem kristal multikomponen. Mekanokimia dianggap sebagai alternatif pendekatan ramah lingkungan karena dilakukan dalam kondisi bebas pelarut atau dengan adanya pelarut dalam jumlah minimal. Artikel review ini dibuat dengan metode instrumen pencarian online terbitan internasional yang akan membahas definisi dan sejarah kokristal farmasi, teknik pembuatan kokristal, sejarah dan definisi mekanokimia, metode mekanokimia pada pembuatan kokristal farmasi, mekanisme metode mekanokimia, serta keuntungan dan kerugian metode mekanokimia. Oleh karena itu pada ulasan ini dijelaskan dan dibahas relevansi prosedur mekanokimia dalam pembentukan kristal multikomponen yang fokus pada kokristal farmasi. Selain itu pada akhir tinjauan ini juga dilaporkan ringkasan makalah ilmiah tentang sintesis mekanokimia kokristal farmasi.
Karakteristik Face Scrub dari Sediaan Simplisia Rumput Laut Sargassum sp
Authors: Nusaibah Nusaibah , Cempaka Cika Issabela , Abrian Satriya , Susanti Oktora , Andayani Tri Rahayu
Published: November 2023

Penggunaan antioksidan sintetik seperti BHA, BHT dan TBHQ dalam pembuatan kosmetik memiliki efek memicu pertumbuhan kanker. Oleh karena itu, diperlukan agen antioksidan alami yang aman digunakan untuk kulit. Sargassum sp. adalah alga coklat yang memiliki aktivitas antioksidan yang tinggi dan dapat dimanfaatkan sebagai agen antioksidan alami untuk pembuatan face scrub. Face scrub adalah salah satu jenis kosmetik yang memiliki fungsi mengangkat sel-sel mati sehingga kulit tidak terlihat kusam. Tujuan dilakukan penelitian ini adalah untuk mengetahui formulasi terbaik dan pengaruh penambahan Sargassum sp. terhadap aktivitas antioksidan dan karakteristik face scrub. Formula yang digunakan yaitu F0 sebagai kontrol, F1 penambahan Sargassum sp. sebanyak 1%, F2 3% dan F3 5%. Pengujian yang dilakukan meliputi uji hedonik, antioksidan dengan metode FRAP, pH dan uji kelembapan. Analisis data hedonik dan kelembapan menggunakan uji Kruskal wallis dengan uji lanjut Mann Whitney-U dan pH menggunakan One way ANOVA dengan uji lanjut beda nyata terkecil (BNT). Hasil uji penelitian menunjukkan F2 merupakan formulasi terbaik dengan Nilai IC50 sebesar 652,99 ppm, pH sebesar 6,42, kelembapan 64,66% dan uji hedonik disukai terutama parameter ketampakan dan tekstur. Penambahan Sargassum sp. terbukti dapat memengaruhi nilai antioksidan, hedonik, pH dan kelembapan produk face scrub.
Formulasi Krim Deodoran-Antiperspiran Alami yang Mengandung Kombinasi Minyak Atsiri Sebagai Pengaroma
Authors: Mayangsari Fransisca Dita , Pratiwi Elasari Dwi , Sari Diah Indah Kumala , Aula Nurwanda Friska Selsabillah
Published: November 2023

Masyarakat pada umumnya menggunakan produk krim deodoran-antiperspiran untuk menghilangkan bau badan. Namun, sebagian produk krim deodoran-antiperspiran dipasaran mengandung alumunium klorohidrat yang berpotensi menyebabkan kanker payudara bila digunakan terus menerus dalam jangka panjang. Pada penelitian ini dibuat formulasi sediaan natural krim deodoran-antiperspiran cream dengan bahan aktif tawas dan zinc ricinoleat. Namun, sediaan ini tidak memiliki aroma. Sedangkan aroma adalah salah satu aspek terpenting pada kosmetik. Salah satu cara yang dapat dilakukan untuk mengatasi hal ini adalah dengan menambahkan minyak atsiri. Tujuan dari penelitian ini adalah untuk membandingkan karakteristik fisik, stabilitas fisik serta tingkat kesukaan (hedonik) dari natural krim deodoran-antiperspiran cream yang mengandung kombinasi minyak atsiri (1% minyak jeruk manis dan 1% minyak nilam) (FB) dan tanpa kombinasi minyak atsiri (FA). Karakteristik dan stabilitas fisik yang diamati meliputi organoleptis, homogenitas, pH, daya sebar dan viskositas. Sedangkan pada uji tingkat kesukaan, yang diamati meliputi tekstur, warna, dan aroma. Hasil uji organoleptis dianalisis secara deskriptif. Hasil pH, daya sebar, viskositas dan hedonik dianalisis secara statistik menggunakan SPSS. Berdasarkan penelitian yang telah dilakukan, dapat disimpulkan bahwa penambahan kombinasi minyak atsiri (minyak nilam dan minyak jeruk manis) berpengaruh pada aspek aroma, warna dan pH dari natural krim deodoran-antiperspiran cream. Penambahan kombinasi minyak atsiri juga berpengaruh terhadap tingkat kesukaan. Panelis lebih menyukai aroma dari sediaan yang mengandung kombinasi minyak atsiri. Pada uji stabilitas fisik, diketahui bahwa penambahan kombinasi minyak atsiri mempengaruhi pH dan viskositas sediaan selama periode penyimpanan selama 90 hari pada suhu ruang (25°C ± 2°C).
Síntesis y caracterización de La₁-ₓSrₓFe₁-ᵧCoᵧO₃±δ para su aplicación como cátodo en una CCOS
Authors:   , de la Huerta Hernández Gloria Elena
Published: November 2023

El progreso de la humanidad ha estado siempre ligado al uso y aprovechamiento de las fuentes de energía. Actualmente, las fuentes de energía usadas provocan una considerable emisión a la atmósfera de CO₂, así como de otros gases y partículas sólidas dando como resultado serios daños al medio ambiente y a la salud, esto ha llevado al desarrollo de alternativas como fuentes generadoras de energía con una producción más amigable con el medio ambiente. Entre estas alternativas, se encuentran las celdas de combustible, donde las celdas de combustible de óxidos sólidos (CCOS), se caracterizan por ser dispositivos que producen electricidad directamente de un combustible gaseoso debido a la combinación electroquímica de éste y un oxidante, las CCOS están compuestas esencialmente por dos electrodos y un electrolito. Este trabajo está enfocado en la síntesis de materiales catódicos, con una estructura tipo perovskita de doble sustitución (AA’BB’O₃) con base lantano en el sitio A y hierro en el sitio B, con fórmula general La₁-ₓSrₓFe₁-ᵧCoᵧO₃±δ, (LSFC), en dicha familia se buscó mejorar sus propiedades estructurales, morfológicas, estabilidad térmica y propiedades de transporte a partir del método de síntesis, considerando el método de sol–gel (Pechini modificado) y el método de sonosíntesis. Se encontró que el método de sonosíntesis permite obtener estructuras cristalinas con simetría cúbica, parámetro de red a= 3.9 Å, con propiedades ópticas y de transporte que presentan valores similares por ambos métodos de síntesis, mientras que el tamaño de cristal y de grano presentan un valor menor en las muestras obtenidas por sonosíntesis siendo estas una mejora respecto a las muestras sintetizadas por sol-gel, por lo que el uso de sonosíntesis es un método alternativo viable en la obtención de este tipo de materiales, con resultados adecuados para su uso como cátodo en una CCOS.
Impact of big data analytics in project success: Mediating role of intellectual capital and knowledge sharing
Authors: Norena-Chavez Diego , Thalassinos Eleftherios
Published: November 2023

Purpose: This study empirically investigates the effect of big data analytics (BDA) on project success (PS). Additionally, in this study, the investigation includes an examination of how intellectual capital (IC) and (KS) act as mediators in the correlation between BDA and KS. Lastly, a connection between entrepreneurial leadership (EL) and BDA is also explored. Design/Methodology- Using a sample of 422 senior-level employees from the IT sector in Peru. The partial least squares structural equation modeling technique tested the hypothesized relationships. Findings- According to the findings, the relationship between BDA and PS is mediated by structural capital (SC) and relational capital (RC), and BDA demonstrates a positive and noteworthy correlation with PS. Furthermore, EL is positively associated with BDA in a significant manner. Practical implications- The finding of this study reinforce the corporate experience of BDA and suggest how senior levels of the IT sector can promote SC, RC, and EL. Originality/Value- This study is one of the first to consider big data analytics as an important antecedent of project success. With little or no research on the interrelationship of big data analytics, intellectual capital and knowledge sharing the study contributes by investigating the mediating role of intellectual capital and knowledge sharing on the relationship between big data analytics and project success.
Abdominal computed tomography and exploratory laparotomy have high agreement in dogs with surgical disease
Authors: Sevy Julia J. , White Robin , Pyle Shannon M. , Aertsens Adrien
Published: November 2023

OBJECTIVE

To compare the results of abdominal CT with exploratory laparotomy in the dog.

ANIMALS

100 client-owned dogs from 1 academic institution.

METHODS

Medical records were searched for dogs that had undergone a preoperative abdominal CT scan read by a board-certified veterinary radiologist followed by an exploratory laparotomy. CT and surgical reports were compared.

RESULTS

The overall agreement between abdominal CT scan and exploratory laparotomy in all cases was 97%. Overall, there was no evidence that proportion agreement differed on the basis of body condition score, time interval between CT and surgery, or oncologic versus nononcologic disease.

CLINICAL RELEVANCE

Abdominal CT scan read by a board-certified diplomate is a sensitive presurgical diagnostic tool for surgical abdominal disease in the dog. When performing a specific abdominal surgery, it is acceptable for the surgeon to fully explore the abdomen or forego it for a smaller approach to the organ of interest if an abdominal CT was performed prior.
Exocrine pancreatic insufficiency in dogs and cats
Authors: Cridge Harry , Williams David A. , Barko Patrick C.
Published: November 2023

Exocrine pancreatic insufficiency (EPI) is a malabsorptive syndrome caused by insufficient secretion of digestive enzymes from pancreatic acini. The most common causes of EPI in dogs and cats are pancreatic acinar atrophy and chronic pancreatitis. EPI is diagnosed by measurement of species-specific immunoassays for serum trypsin-like immunoreactivity, the concentration of which directly reflects the mass of functioning pancreatic acinar tissue. EPI is treated by pancreatic enzyme replacement therapy, nutritional management (low-residue diets with moderate fat content), and supplementation of cobalamin. Some dogs and cats have persistent clinical signs despite these treatments. Growing evidence suggests that these clinical signs may be due to enteric microbiota dysbiosis or the presence of concurrent diseases such as chronic enteropathies. Management of these abnormalities may improve outcome in dogs and cats with EPI. The long-term prognosis for dogs and cats with EPI is generally good if high-quality medical therapy is provided. Future studies are needed to further understand the causes of persistent dysbiosis in animals with EPI following initiation of pancreatic enzyme replacement therapy and assess the efficacy of treatments to ameliorate these abnormalities.
Economic Crisis Adaptation in Sri Lankan Construction Industry: Pathway to Prosperity
Authors: Weerakoon Thilina Ganganath , Wimalasena Sulaksha , Fedotova Kristine
Published: November 2023

The construction industry is a critical sector in the nation’s economic growth, accounting for a sizable share of GDP growth. However, it is the most vulnerable industry to a financial depression, whether local or worldwide. The present economic crisis has had an impact on the Sri Lankan construction industry, with more than half a million employees lost their jobs in the previous year. Many major construction firms have either paused or abandoned their projects and shifted to overseas construction. Therefore, understanding the consequences of financial crises regarding construction initiatives in Sri Lanka, as well as anticipated post-crisis growth paths in this sector, necessitates a thorough examination. The goal of this study is to extensively examine the consequences of the 2022 economic crisis on Sri Lankan construction projects and investigate remedies that might start a post-crisis rebound. The study utilized a mixed-method approach, combining quantitative and qualitative research methods. Purposive sampling was used to choose construction industry participants from various backgrounds in order to get a varied range of perspectives. The findings of this study not only emphasize the negative consequences of the crisis but also reveal prospects for development within the industry. The article offers construction professionals and other industry stakeholders useful insights about the foreseeable future of the country’s construction sector. The research looks at prospective growth areas such as the development of infrastructure, sustainable construction strategies, and the usage of emerging technology. The findings of the research can help to ensure that the sector has a robust and productive future.
Mengartikulasikan tradisi kritis dalam riset kualitatif bidang psikologi di Indonesia
Authors: Yulianto Jony Eko
Published: November 2023

Artikel ini merespons catatan editorial di Jurnal Psikologi Ulayat yang ditulis oleh Lestari (2021), yang mengadvokasi pentingnya memiliki tradisi kritis dalam melakukan penelitian kualitatif bidang psikologi di Indonesia. Dalam membangun gagasannya, penulis mendiskusikan; (1) mengapa tradisi kritis merupakan sebuah pendekatan yang penting untuk riset kualitatif bidang psikologi di Indonesia; dan (2) bagaimana kita dapat mengartikulasikan tradisi kritis dalam penelitian-penelitian kita. Berpijak pada konsep-konsep dalam riset ulayat seperti phronesis, kekerasan epistemologis, dan kekerasan ontologis, artikel ini mendiskusikan pentingnya peneliti dapat berkontribusi dalam menyelesaikan isu sosial melalui riset. Analisis-analisis dalam artikel ini didasarkan pada konteks sosio-historis dari bidang ilmu psikologi untuk menekankan pentingnya memiliki pluralisme pendekatan riset. Upaya untuk meninjau kembali konteks sejarah psikologi merupakan hal yang fundamental karena dapat membantu mengingatkan peneliti untuk menempatkan etnis ulayat sebagai subjek dan bukan objek penelitian. Di akhir bagian, penulis mendiskusikan enam cara untuk meningkatkan kualitas riset kualitatif yang dilakukan dengan etnis ulayat di Indonesia.
GAMBARAN ATTITUDES AND OPINIONS DISCLOSURE PADA MANAJEMEN KONFLIK PASANGAN DEWASA MUDA
Authors: Prabandari Darlyss Chatarina Elsa , Suryadi Denrich
Published: November 2023

Salah satu tugas perkembangan pada masa dewasa muda yakni menjalin hubungan romantis dengan lawan jenis. Pada dasarnya, hubungan berpacaran merupakan bentuk penjajagan dari hubungan intim, yang melalui relasi tersebut harapannya kedua individu mampu untuk belajar saling mengenal dan memahami lebih dalam satu sama lain. Namun, adanya perbedaan atau pertentangan pola pikir, sikap dan sudut pandang tertentu dapat menyebabkan konflik relasional. Self-dislcosure dalam teori penetrasi sosial berguna untuk memahami kualitas dan meningkatkan keterhubungan serta dukungan sosial yang lebih baik, melalui salah satu aspek yang mendasari perbedaan individu yakni keterbukaan pada sikap dan pandangan personal. Meskipun konflik dalam hubungan dapat menyebabkan munculnya pengaruh negatif bagi individu maupun keberlangsungan hubungan, konflik juga dapat memberikan evaluasi yang lebih baik dari suatu relasi romantis yang dimaksudkan untuk menciptakan strategi manajemen konflik melalui komunikasi. Metode yang digunakan dalam penelitian ini adalah pendekatan kualitatif fenomenologi melalui wawancara mendalam terhadap tiga pasangan pria dan wanita dalam rentang usia dewasa muda 19-40 tahun yang telah menjalin hubungan romantis minimal selama satu tahun. Penelitian ini menemukan bahwa keterbukaan diri dalam hal sikap dan pandangan personal berpengaruh positif dalam rangka memediasi manajemen konflik dengan pasangannya. Saat mengekspresikan dirinya selama konflik, adanya determinasi sosial dan peran gender turut mempengaruhi bagaimana individu berperilaku. Para subyek menunjukkan adanya beragam gaya manajemen konflik dengan jenis compromising style, integrating style, obligin style, dominating style, dan avoiding style.
PERAN SELF – EFFICACY TERHADAP KEPUASAN MAHASISWA PADA MASA PEMBELAJARAN POST COVID–19 DENGAN MOTIVASI SEBAGAI MODERATOR
Authors: Saputra Mikhael Adam , Heng Pamela Hendra , Dewi Fransisca Iriani Roesmala
Published: November 2023

Pada akhir tahun 2022, Peraturan Pembatasan Kegiatan Masyarakat (PPKM) telah resmi dicabut serta memasuki transisi pada masa post COVID–19. Sektor seperti pendidikan perguruan tinggi juga kembali mengalami peralihan, sepert metode belajar mengajar yang kembali secara luar jaringan (luring) atau hybrid, layanan administrasi yang juga kembali secara luring atau hybrid, dan adanya perubahan kurikulum pada sistem pendidikan saat ini. Berbagai perubahan dalam metode belajar mengajar, layanan administrasi, serta kurikulum memberikan dampak terhadap self–efficacy dan motivasi mahasiswa yang berkaitan dengan kepuasan. Tujuan dari penelitian ini adalah melihat peran self–efficacy terhadap kepuasan mahasiswa pada masa endemi COVID–19 yang dimoderasi dengan motivasi. Penelitian melibatkan 502 responden, dengan metode pengumpulan data menggunakan kuesioner yang terdiri atas General Self–Efficacy Scale (GSES) (α = 0.667), Course Satisfaction Scale (α = 0.575), dan Academic Motivation Scale (AMS) (α = 0.742). Hasil temuan dalam penelitian ini, didapati korelasi positif antara kepuasan self–efficacy dengan kepuasan mahasiswa (r = 0.455), korelasi positif antara self–efficacy dan motivasi (r = 0.138), serta korelasi positif antara motivasi dan kepuasan mahasiswa (r = 0.216). Didapati juga peran self–efficacy terhadap kepuasan mahasiswa sebesar 29,9% (R² = 0.299) mengalami peningkatan menjadi 32% (R² = 0.320) setelah dilakukan pengujian self–efficacy dengan moderator motivasi. Dapat disimpulkan bahwa motivasi terbukti berperan sebagai moderator dalam penelitian ini.
Wakaf Produktif dan Peranannya dalam Mengentaskan Kemiskinan di Indonesia
Authors: Yasniwati Yasniwati
Published: November 2023

Waqf is one of the Islamic philanthropies that can help people get rid of poverty. Productive waqf is one of the economic media that we can use to help the government in terms of poverty alleviation. As one of the pillars of community welfare, waqf institutions have a significant role that can be felt by the community, especially in improving people's lives, especially when productive waqf is managed by professional nazhir such as schools established by waqf-based foundations where schools are free, then also the people who are around the school also feel the benefits such as they can trade around the school and the results of their efforts can help to fulfill their daily needs. The potential of productive waqf today if it is managed by a professional nazhir then productive waqf can realize people's welfare and help the government in eradicating poverty
Validation of Ukrainian language versions of gender bias detection inventorie
Authors: Yaroshenko Alla , Semigina Tetyana
Published: November 2023

One of the most common research tools for studying sexism is Sandra Bem's Gender Role Inventory and Peter Glick and Susan Fiske's Ambivalent Sexism Inventory. The aim of our work is to translate the original questionnaire texts for studying gender biases into Ukrainian and to conduct their validation with both professionals and social work clients.

The validation of the translated research tools was carried out at the Kyiv Municipal Center for Social Services and included three focus groups with 23 professionals (social workers, psychologists) and a survey of 83 candidates for creating family education forms who underwent training at the center. Mathematical processing of the results was carried out using the IBM SPSS Statistics program, using comparative, descriptive, and correlation analysis.

During the work with the questionnaires, participants in the study did not have difficulties in understanding the statements contained in the questionnaires or using the questionnaire keys. Analysis of the survey results using our translation of the S. Bem questionnaire indicates that almost one-third of respondents' answers about women contain high scores on the femininity scale, while their responses about men score high on the masculinity scale. The respondents' answers suggest that their perceptions of women and men as androgynous personalities are complemented by sex-typed perceptions of their qualities. This may indicate support for the candidates for creating family education forms with ambivalent sexism views. The use of the Glick and Fiske questionnaires revealed that respondents demonstrate more benevolent than hostile sexism. At the same time, the level of hostile and benevolent sexism was higher in men than in women.

Validation of the Ukrainian versions of two questionnaires in focus groups with professionals and during the survey of candidates for creating family education forms confirmed the possibility of using adapted Ukrainian versions to study gender biases in Ukraine.
UML MODELING OF THE ENTERTAINMENT AND HOTEL MENU PLANNING APPLICATION DEVELOPMENT PROCESS
Authors:   State University “Zhitomir polytechnic”, Kravchenko Svitlana , Suhoniak Inna ,   State University «Zhitomir polytechnic», Marchuk Halyna ,   State University «Zhitomir polytechnic», Gryshkun Yevheniy ,   State University «Zhitomir polytechnic», Shved Oksana ,   State University «Zhitomir polytechnic»
Published: November 2023

The object of the study is the principle of applying the UML modeling model for the process of building a web application for planning entertainment and hotel menus.The analysis of the study of this area of similar processes and the conduct of own research, which in turn require a more in-depth immersion in the very essence of the scientific area and expanding the horizons for further research, has been carried out.The work algorithm and states of the software system, physical model are determined. The application of the object-oriented model of the system was demonstrated, and the design of the software product was carried out. The UML model was used to visualize and optimize the presentation of the application.The work defines the analysis of requirements, conceptual modeling of the construction of the site development model. The main stages of creating the application are analyzed. The functional possibilities of using UML modeling in application development are characterized
DETERMINATION OF THE EFFICIENCY OF SULFATE REMOVAL ON A LOW-PRESSURE REVERSE OSMOSIS MEMBRANE
Authors:   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Gomelya Mukola , Trus Inna ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Hlushko Olena ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute», Makarenko Iryna ,   National Technical University of Ukraine «Igor Sikorsky Kyiv Polytechnic Institute»
Published: November 2023

The dependence of the efficiency of the low-pressure reverse osmosis membrane Filmtec TW30-1812-50 on the initial concentrations of sodium sulfate in the range of 10-650 mg/dm3 at permeate recovery rates of 1-90 % using a pressure of 4 atm was determined. The effect of increasing the permeate recovery rate on selectivity, membrane performance, and the in-crease in the sulfate content of concentrates was determined. It is shown that the concentration of sulfates in permeate depends on their initial concentration in solutions and increases both with an increase in the initial concentration and with an increase in the degree of permeate extraction. The latter factor is quite significant at initial sulfate concentrations of 650 mg/dm3. The membrane performance increases with decreasing salt content in water and decreases with increasing permeate removal rate, which leads to an increase in salt concentration in the pre-membrane space. The selectivity of the membrane for sulfates is 94.9-99.3 % and increases with increasing concentration of sodium sulfate solutions in solutions, despite a certain increase in salt concentrations in permeates. It is shown that as the degree of permeate selection increases, the selectivity for solutions with low initial sulfate concentrations increases. A FFP-based process modeling was performed to determine the sulfate con-centration in the permeate and concentrate at any initial sulfate concentration in a certain range. It was found that the con-centrate solutions are stable in the entire range of concentrations used with an increase in the degree of permeate recovery from 10 to 90 %. Based on the research results, a method for determining the capacity of the plant and the osmotic and oper-ating pressures based on the salt concentration and the set pressure in the system was proposed. From the data obtained, it can be concluded that the permissible level of mineralization at which the use of low-pressure reverse osmosis membranes is ad-visable.
RELATIONSHIP OF L. MONOCYTOGENES MOTILITY CHARACTERISTICS WITH INVASION INTO HEP-2 CELLS
Authors:   Joint Institute of High Temperatures RAS, Moscow, Abdulkadieva M.M. , Litvinenko V.V. , Vasilyeva E.V. , Sysolyatina E.V. , Ermolaeva S.A. ,   Gamaleya National Research Center for Epidemiology and Microbiology, Moscow
Published: November 2023

The motility allows free-living microorganisms to spread and develop new habitats, and pathogenic ones to realize their virulence. The characteristics of the motility of bacterial cells include trajectories, speeds and collective movement. It has been shown for E. coli strains, that these characteristics affect adhesion to abiotic and biotic surfaces [1]. The aim of the work is to investigate the contribution of L. mononcytogenes motility to HEp-2 cells to invasion.
19F-ELECTRON NUCLEAR DOUBLE RESONANCE (ENDOR) SPECTROSCOPY FOR DISTANCE MEASUREMENTS IN DNA-DUPLEXES
Authors:   Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Asanbaeva N.B. , Novopashina D.S. , Rogozhnikova O.Yu. , Tormyshev V.M. , Sukhanov A.A. , Shernyukov A.V. , Genaev A.M. , Lomzov A.A. , Kehl A. , Bennati M. , Meyer A. , Bagryanskaya E.G. ,   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk,   Zavoisky Physical-Technical Institute, FRC KazSC RAS, Kazan,   Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany,   Georg August University of Göttingen, Germany
Published: November 2023

The combination of 19F-labeling and pulsed electron-nuclear double resonance (ENDOR) is a powerful method for obtaining structural information about biomolecules. In this work, we demonstrated the capability of Mims 19F-ENDOR experiments on measuring intermolecular distances in trityl- and 19F-labeled DNA duplexes at three electron paramagnetic resonance frequencies (34, 94, and 263 GHz).
CHARACTERIZATION OF PROTEORHODOPSIN OF BACTERIA FOUND IN ANTARCTICA
Authors:   Moscow Institute of Physics and Technology, Dolgoprudny, Zagryadskaya Yu.A. , Lyubaykina N.A. , Khrapov S.E. , Dolotova S.M. , Gavrilenkova A.A. , Petrovskaya L.E. , Okhrimenko I.S. ,   Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow
Published: November 2023

Few of the large number of metagenomically found rhodopsins have been characterized and are being used as optogenetic tools or have biotechnological applications (or potential). We obtained new unusual data while characterizing the microbial rhodopsin from an Antarctic bacterium living at the close to the zero annual temperatures and moderate UV radiation.
DETECTION OF DAMAGE IN THE STRUCTURE OF THE DNA MOLECULE, CAUSED BY VARIOUS TYPES OF IONIZING RADIATION
Authors:   Saint Petersburg State University, Ivanova D.N. , Kotb O.M. , Brozhik D.S. , Verbenko V.N. , Gulevich E.P. , Ezhov V.F. , Karlin D.L. , Murzakova I.F. , Pak F.A. , Paston S.V. , Fomin E.V. , Khalikov A.I. ,   Zagazig University, Egypt,   Konstantinov Petersburg Nuclear Physics Institute, Gatchina
Published: November 2023

In the present work we study changes in the structure of DNA under the action of various ionizing radiations: protons with an energy of 1 GeV, 60Co gamma radiation with photons energies of 1.17 MeV and 1.33 MeV, and soft X-ray radiation with an average photon energy of 60 keV. The dose dependences of the DNA melting temperature and the radiation-chemical yield of destruction of nitrogenous bases were obtained at radiation doses of 0–100 Gy
CONTROLLING THE SHAPE AND MOLECULARITY OF RNA COMPLEXES FORMED BY A PAIR OF OLIGONUCLEOTIDES
Authors:   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Kanarskaya M.A. , Lomzov A.A. ,   Novosibirsk State University
Published: November 2023

The nucleic acids secondary and tertiary structures largely determine their biological functions. The structure of RNA complexes formed by oligonucleotides pair has been studied. The depending of such complexes type and size on the length of the linker connecting duplex sections has been determined. The interaction of complexes with an opener and a stopper has been investigated, aimed at investigating the possibility of directional regulation of the shape and molecular structure of complexes. The possibility of cyclic complexes linearization and their reverse cyclization has been shown.
A case of central serous chorioretinopathy after a blast injury
Authors:   Main Military Clinical Hospital of the National Guard Troops of the Russian Federation», Balashikha, Russian Federation, Vorobiev P.P. , Parkhomenko I.V. ,   Main Military Clinical Hospital of the National Guard Troops of the Russian Federation», Balashikha, Russian Federation
Published: November 2023

Relevance. Over the past decade, clinical cases of central serous chorioretinopathy after an eye injury have increasingly appeared in the press. Purpose. Currently, there are no cases of description of central serous chorioretinopathy after an explosive injury in the literature available for review. Presenting our clinical case, we will try to fill this gap. Methods. A 41-year-old man with concomitant injuries was admitted to inpatient treatment at a multidisciplinary clinic after a close detonation of a high-powered explosive device. At the end of the second week from the moment of injury, against the background of an improvement in the general well-being of the patient, the «flickering spot» in front of the gaze of the left eye began to actively disturb. On the 21st day after injury, both eyes were examined using an optical coherence tomograph with a rocking source (OCT) DRI OCT Triton by Topcon (Japan). In the lower quadrants on the edge of the macula of the left eye, a serous detachment of the neuroepithelium was detected with dimensions of 5310×5253 μm and a maximum height of 706 μm with two detachments of the retinal pigment epithelium. On the 28th day from the moment of injury, during the control OCT study, flattening was noted, but with an increase in the area of serous detachment of the neuroepithelium and the preservation of detachments of the retinal pigment epithelium. In connection with the professional requirements for the patient's state of health, delimiting laser coagulation of the retina was performed against the background of the treatment of concomitant pathology. Results and discussion. On the 33rd day after the injury, complete adherence of the serous detachment of the neuroepithelium and detachments of the retinal pigment epithelium was noted with the disappearance of the patient's complaints. Conclusion. The presented clinical case is of great interest, since eye trauma and, in particular, explosive trauma are quite rare causes of the development of central serous chorioretinopathy. Key words: clinical case, serous chorioretinopathy, neuroepithelial detachment, pigment epithelium detachment, blast injury, post-traumatic retinopathy, eye injury
Antagonistic activity of Trichoderma crassum Gmaxr1 against Macrophomina phaseolina Gmax20 of the Soybean Crop
Authors: Tripathi Ajay Raj , Dwivedi Shiv Kumar
Published: November 2023

Charcoal rot is a fungal disease of soybean caused by Macrophomina phaseolina. Soybean contains proteins, vitamins and fats. It is an important source of nutrition in developing countries. In the present study, Macrophomina phaseolina Gmax20 was isolated from soybean-infected plant whereas Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus and Trichoderma crassum Gmaxr1 were isolated from a healthy soybean plant’s intact rhizospheric soil. The isolated antagonists were tested against the Macrophomina phaseolina Gmax20 under in vitro conditions. The results showed that T. crassum Gmaxr1 showed the highest inhibition percentage (16.98%, 23.08% and 54.04%) on 1st, 2nd and 3rd day than other selected antagonists against M. phaseolina Gmax20. Thus, due to the maximum inhibition percentage of T. crassum Gmaxr1 against M. phaseolina Gmax20, it can be exploited as a proficient bioagent for the management of charcoal rot disease.
Diabetic wound healing activity of Elaeagnus conferta Roxb. leaf ethanol extract
Authors: Nayaka Sachin S. , Krishna V. , Narayana J. , Ravi Kumar S. , Santosh Kumar S.R.
Published: November 2023

High blood glucose level and gangrene wounds are becoming difficult to cure for the medical sciences nowadays. The goal of the current study is to assess the diabetic wound healing activity of Elaeagnus conferta leaf ethanol extract (LEE). The qualitative and quantitative phytochemical screening of the LEE revealed the presence of total phenols (42.20 ± 1.3 μg/gm) and flavonoids (45.23 ± 1.2 μg/gm). HR-LCMS analysis of the LEE revealed the presence of 27 phytoconstituents, among them Telmisartan was expressed with higher concentration. Alloxan monohydrate induced diabetic rats were administered with LEE of Elaeagnus conferta and the extract was locally applied to excision, incision and dead space wound models of diabetic rats. LEE at the concentration of (200 mg /kg. /bw.) significantly reduced the blood glucose levels when compared to the untreated diabetic group. In excision wound models on 21st day of treatment, the percentage of epithelization was increased to 99.86±0.08 and in the incision model, tensile strength of the wound was increased to 798.7±37.08gm as compared to Povidine iodine ointment. In slico molecular docking studies of the Telmisartan ligand with the glycogen synthase kinase- 3 protein resulted with 2 hydrogen bonds and 13 hydrophobic interactions indicating the suppression of wound enhancing protein. Present study authenticates the antidiabetic property and wound healing efficacy of E. conferta leaf ethanol extract.
Molecular characterization of Marek's disease virus revealing the predominance of high-virulence MDV in Vietnam
Authors: Khue Thi Nguyen , Nguyen Thi Thu Hien , Le Thi Thanh Huyen , Roan Thi Do , Huong Thi Thanh Doan
Published: November 2023

Marek's disease (MD) is a potentially fatal viral disease caused by the Gallid alphaherpesvirus 2 (GaHV-2). The outbreaks are common in both unprotected and vaccinated flocks. The carcinogenic serotype MDV-1 was found using a PCR method in five northern provinces and two central provinces of Vietnam from 2019 to 2022. The Meq gene from 13 MDV-1 strains was sequenced in its entirety, containing 1020 nucleotides encoding 339 amino acids. The examination of these genomes revealed that all strains discovered in Vietnam correspond to the pathotypes known as highly virulent (vv). This classification was based on the presence of low proline concentration (from 20.59-21.18%) in the Meq which consisted of three PPPP motifs and three interrupted motifs. The interrupted motifs are characterized by mutations at the second position of the proline-rich region where the original PPPP sequence is altered to PPPP>P (Q / A / R) PP. Furthermore, the Vietnamese GaHV-2 strains in this study had the most similarity to high-virulence Chinese strains but had the lowest similarity to the currently used CVI988 vaccination. It is worth noting that no strains from the moderate pathogenicity (mv) or very virulence plus (vv+) groups were found among the Vietnamese isolates. The findings shed light on previously unknown molecular features of Marek's disease virus strains in Vietnam's northern provinces. The study's findings add to a better understanding of MDV in Vietnam, filling an important information gap. This knowledge can help guide efforts to reduce the burden of Marek's disease on the chicken business, improve disease prevention and control strategies and select the best vaccine for chickens in the field.
Structural Trends and Vibrational Analysis of N,N,N′,N′- Tetramethylmalonamide Complexes Across the Lanthanide Series
Authors: Kravchuk Dmytro , Wang Xiaoyu , Servis Michael , Wilson Richard
Published: November 2023

Fundamental understanding of coordination chemistry across the lanthanide series is essential for explaining chemical behavior of rare-earth metals in complex liquid-liquid extraction processes, which in turn affects the distribution ratios and efficacy of separations as a whole. In this work, we explore the structural trends between the lanthanides and a neutral N,N,N′,N′-tetramethylmalonamide (TMMA) ligand within four isolated families of solid-state compounds: Ln(trans-TMMA)2(NO3)3 Ln = La-Nd, Sm; Ln(cis-TMMA)2(NO3)3 Ln = Eu-Tb, Er; [Ln(TMMA)3(NO3)2][Ln(TMMA)(NO3)4] Ln = Dy-Tm; Ln(Κ2-TMMA)(iPrOH)(NO3)3 and Ln(Κ1-TMMA)(Κ2-TMMA)(NO3)3 Ln = Yb, Lu. Moving across the lanthanide series, we note the formation of both discrete charge-neutral complexes, as well as charged molecular anion-cation pairs, with variations in spatial ligand arrangement, coordination numbers, and ligand denticities. IR and Raman spectroscopy paired with DFT frequency calculations were used for an in-depth investigation of vibrational modes unique to each structural family. The collection of isolated model compounds was also discussed in the context of liquid-liquid separations based on reported distribution ratios from malonamide extraction.
Invariant Features for Accurate Predictions of Quantum Chemical UV-vis Spectra of Organic Molecules
Authors: Baker Justin , Lupo Pasini Massimiliano , Hauck Cory
Published: November 2023

Including invariance of global properties of a physical system as an intrinsic feature in graph neural networks (GNNs) enhances the model’s robustness and generalizability and reduces the amount of training data required to obtain a desired accuracy for predictions of these properties. Existing open source GNN libraries construct invariant features only for specific GNN architectures. This precludes the generalization of invariant features to arbitrary message passing neural network (MPNN) layers which, in turn, precludes the use of these libraries for new, user-specified predictive tasks. To address this limitation, we implement invariant MPNNs into the flexible and scalable HydraGNN architecture. HydraGNN enables a seamless switch between various MPNNs in a unified layer sequence and allows for a fair comparison between the predictive performance of different MPNNs. We trained this enhanced HydraGNN architecture on the ultraviolet-visible (UV-vis) spectrum of GDB-9 molecules, a feature that describes the molecule’s electronic excitation modes, computed with time-dependent density functional tight binding (TD-DFTB) and available open source through the GDB-9-Ex dataset. We assess the robustness (i.e., accuracy and generalizability) of the predictions obtained using different invariant MPNNs with respect to different values of the full width at half maximum (FWHM) for the Gaussian smearing of the theoretical peaks. Our numerical results show that incorporating invariance in the HydraGNN architecture significantly enhances both accuracy and generalizability in predicting UV-vis spectra of organic molecules.
Periodic table screening for enhanced positive contrast in MRI and in vivo uptake in glioblastoma
Authors: Herraiz Aitor , Morales M. Puerto , Martínez-Parra Lydia , Arias-Ramos Nuria , López-Larrubia Pilar , Gutierrez Lucía , Mejías Jesús , Díaz-Ufano Carlos , Ruiz-Cabello Jesús , Herranz Fernando
Published: November 2023

The quest for nanomaterial-based imaging probes that can provide positive contrast in MRI is fueled by the necessity of developing novel diagnostic applications with potential for clinical translation that current gold standard probes cannot provide. Although interest in nanomaterials for positive contrast has increased in recent years, their study is less developed than that of traditional negative contrast probes in MRI. In our search for new magnetic materials with enhanced features as positive contrast probes for MRI, we decided to explore the chemical space to comprehensively analyze the effects of different metals on the performance of iron oxide nanomaterials already able to provide positive contrast in MRI. To this end, we synthesized 30 different iron-oxide-based nanomaterials. Thorough characterization was performed, including multivariate analysis, to study the effect of different variables on their relaxometric properties. Based on these results, we identified the best combination of metals for in vivo imaging and tested them in different experiments. First, we tested its performance on magnetic resonance angiography using a concentration ten times lower than that clinically approved for Gd. Finally, we studied the capability of these nanomaterials to cross the affected blood-brain barrier in a glioblastoma model. The results showed that the selected nanomaterials provided excellent positive contrast at large magnetic field and were able to accumulate at the tumor site, highlighting the affected tissue.