bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribución actual del meloncillo, Herpestes ichneumon (Linnaeus, 1758), en el sur de la provincia de Salamanca y en el norte de la provincia de Cáceres
Authors: Ramos Pedro L. , Merchán Tomás , Rocha Gregorio , Hidalgo de Trucios Sebastián J.
Published: March 2024

Data on the historical presence of Egyptian mongoose Herpestes ichneumon in southern Salamanca (Spain) and northern Cáceres (Spain) are very scarce and they have only been found in a small number of specific sites. This study presents 46 records of presence based on sightings (n=25), road kills (n=5), and deaths from hunting activities (n=1) (all collected between 2002 and 2007), and camera-traps (conducted from January 2005 to December 2006). These reports indicate an increase in the known species distribution, with references to 9 new 10x10-Km UTM squares located in the northern-most area of its present range. These UTM squares are as follows: 29TPE96, 29TPE98, 29TQE08, 29TQE09, 29TQE28, 29TQE29, 29TQE39, 29TQF20 and 29TQF30. Most of the references cover the last 5 years, which seems to confirm the theory suggesting that the species is now expanding into new areas. Information on its photographically documented maximum altitude in Spain is presented, with an individual observed at 1,155 m.a.s.l. This study confirms that the Ciudad Rodrigo (Sierra de Camaces, Spain) municipal area is the most northern area with a regular presence of the species, and that it is also increasing its distribution area to the north-east of Salamanca province, reaching Sierra de Francia-Las Quilamas in the Puebla de Yeltes municipal area.
Efectos de la estructura forestal sobre la ab undancia del topillo rojo Myodes glareolus (Schreber, 1780) en un encinar de la Garrotxa (NE Catalunya)
Authors: Torre Ignasi , Arrizabalaga Antoni
Published: March 2024

The bank vole Myodes glareolus (Schreber, 1780) is a small Eurosiberian forest rodent that lives in the northern third of the Iberian Peninsula. Within its European distribution range, the bank vole is known to prefer forested areas with extensive plant cover (i.e., herbs and shrubs) that provide refuge and food. However, there is a lack of data on its environmental requirements in the Mediterranean, which constitutes the southernmost limit of its distribution. This study analyzed the influence of forest structure on bank vole abundance in a holm-oak forest in La Garrotxa (NE Catalonia, Spain). A total of 34 rectangular plots each containing 8 Sherman traps (4 x 2) were constructed in zones with different structures within the same forest patch. These plots were sampled for 3 consecutive days in winter 1999. The forest structure enabled the definition of two groups of plots based on cluster analysis: 1) one group of 17 plots (type 1) with large oaks and a smaller density of trunks, with a great amount of herbaceous vegetation and shrubs; and 2) a group of 10 plots (type 2), with small oaks and a high density of trunks, with very poor undercover. A third experimental group was added (n = 7 plots), consisting of plots with a structure similar to the type 2 plots, and that were cleared by removing bushes and small trees. A total of 32 different individuals were captured, and analysis of variance demonstrated that the density of bank voles was 9 times higher in type 1 plots than in type 2 plots, whereas there were no captures in type 3 plots. These results indicate microhabitat preferences that are similar to those already known in more northern populations, and that lead to the selection of forest patches with extensive shrub and herbaceous cover.
Distribución espacial y preferencia de hábitat de los micromamíferos en la Cuenca del río Erro (Navarra)
Authors: Galicia David , Escala M. Carmen
Published: March 2024

The distribution of rodents and insectivores along the river Erro was analysed. This river is located in the Western Pyrenees valleys of Navarra, Spain. This study was conducted seasonally for 2 years using Sherman live-traps. To analyse the relationship between habitat and species presence, captures and trapping effort for each biotope were recorded. Although the wood mouse (Apodemus sylvaticus) was the most abundant species - more than 75% of total captures - this sampling method enabled the capture of another 12 species. In addition, if other signs of presence, such as sightings, signals or tracks, are considered, then a total of 21 species of small mammals were detected. The analysis indicated differences between species in habitat preferences. Apodemus flavicollis and Myodes glareolus were associated with deciduous forests in northern areas, whereas Mus spretus and Crocidura russula were associated with crop areas and ecotones in southern areas. Apodemus sylvaticus has been found throughout all the biotopes.
Estudio biométrico preliminar del dimorfismo sexual en visones americanos Neovison vison (Schreber, 1777) de granja y salvajes en el norte de la península ibérica.
Authors: Rodríguez-Refojos Cristina , Zuberogoitia Íñigo
Published: March 2024

The American mink is an invasive species throughout Europe where feral populations have become established in the natural environment due to escapes from fur farms or by intentional release. This study compares captive ranch mink with feral mink from nearby areas using basic biometric measures (weight, total length, body length and tail length) and the physical condition of individuals. We also analyze sexual dimorphism and address the various hypotheses on dimorphism to date. The degree of sexual dimorphism is also compared between the populations to identify any potential differences.
TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves
Authors: Grove Matthew , Kim Hyukmin , Pang Shuhuan , Amaya Jose Paz , Hu Guoqing , Zhou Jiliang , Lemay Michel , Son Young-Jin
Published: March 2024

Previously we showed that the hippo pathway transcriptional effectors, YAP and TAZ, are essential for Schwann cells (SCs) to develop, maintain and regenerate myelin . Although TEAD1 has been implicated as a partner transcription factor, the mechanisms by which it mediates YAP/TAZ regulation of SC myelination are unclear. Here, using conditional and inducible knockout mice, we show that TEAD1 is crucial for SCs to develop and regenerate myelin. It promotes myelination by both positively and negatively regulating SC proliferation, enabling Krox20/Egr2 to upregulate myelin proteins, and upregulating the cholesterol biosynthetic enzymes FDPS and IDI1. We also show stage-dependent redundancy of TEAD1 and that non-myelinating SCs have a unique requirement for TEAD1 to enwrap nociceptive axons in Remak bundles. Our findings establish TEAD1 as a major partner of YAP/TAZ in developmental myelination and functional nerve regeneration and as a novel transcription factor regulating Remak bundle integrity.
Using synchronized brain rhythms to bias memory-guided decisions
Authors: Stout J. J. , George A. E. , Kim S. , Hallock H. L. , Griffin A. L.
Published: March 2024

Functional interactions between the prefrontal cortex and hippocampus, as revealed by strong oscillatory synchronization in the theta (6-11 Hz) frequency range, correlate with memory-guided decision-making. However, the degree to which this form of long-range synchronization influences memory-guided choice remains unclear. We developed a brain machine interface that initiated task trials based on the magnitude of prefrontal hippocampal theta synchronization, then measured choice outcomes. Trials initiated based on strong prefrontal-hippocampal theta synchrony were more likely to be correct compared to control trials on both working memory-dependent and -independent tasks. Prefrontal-thalamic neural interactions increased with prefrontal-hippocampal synchrony and optogenetic activation of the ventral midline thalamus primarily entrained prefrontal theta rhythms, but dynamically modulated synchrony. Together, our results show that prefrontal-hippocampal theta synchronization leads to a higher probability of a correct choice and strengthens prefrontal-thalamic dialogue. Our findings reveal new insights into the neural circuit dynamics underlying memory-guided choices and highlight a promising technique to potentiate cognitive processes or behavior via brain machine interfacing.
Apical constriction requires patterned apical surface remodeling to synchronize cellular deformation
Authors: Yamashita Satoshi , Ishihara Shuji , Graner François
Published: March 2024

Apical constriction is a basic mechanism for epithelial morphogenesis, making columnar cells into wedge shape and bending a flat cell sheet. It has long been thought that an apically localized myosin generates a contractile force and drives the cell deformation. However, when we tested the increased apical surface contractility in a cellular Potts model simulation, the constriction increased a pressure inside the cell and pushed its lateral surface outward, making the cell into not the wedge shape but instead a drop shape. To keep the lateral surface straight, we considered an alternative model in which the cell shape was determined by cell membrane elasticity and endocytosis, and the increased pressure is balanced among the cells. The cellular Potts model simulation succeeded in reproducing the apical constriction, and it also suggested that a too strong apical surface tension might prevent the tissue invagination.
ARCHITECTURE FOR AUTISM: THERAPEUTIC AND EDUCATIONAL CENTRE FOR CHILDREN IN ZAMOŚĆ, POLAND
Authors: Martyka Anna , Małek Wiktoria
Published: March 2024

This article addresses the issue of therapeutic and educational centres for children with autism. Autism, which affects perception and behaviour, requires specialised care, of which the built environment is crucial. This article presents the concept of a centre that meets the individual needs of children with autism, promoting a safe and welcoming environment for their development. Particular emphasis is placed on spatial aspects that facilitate social interaction and tranquillity. The paper is based on research in the literature and analysis of the collected information, offering new insights into the design of educational spaces for children with autism.
Triple Problems of Nepalese Hills: Low Income, Migration and, Land Use Changes – One Possible Solution: Specialty Rice
Authors: Upreti Raj
Published: March 2024

The hills of Nepal face a complex triad of interrelated challenges: low income, outmigration, and land abandonment leading to aquifer desiccation, with low income serving as the precursor of this vicious cycle. The Nepalese hills harbor two significant yet underutilized potentials. First, the picturesque terraces, a legacy of preceding generations, are unfortunately abandoned and neglected. Second, these hills harbor diverse landrace varieties of rice, each with unique traits, though only a limited number among them have received the deserved recognition and fair market prices. This study seeks to identify and analyze these rice varieties, investigate their value chain, and conduct a comparative cost-benefit analysis against other rice varieties across Nepal to evaluate their economic feasibility. This study, conducted across 12 districts in Eastern Nepal, involved 12 focused group discussions with rice farmers, 200 individual interviews with rice farmers, as well as 10 individual interviews each with rice millers, agro vets, and rice traders. The research employed cost-benefit analysis as a tool to assess economic feasibility. The findings indicated that some of these rice varieties demonstrate a benefit-to-cost ratio ranging from two to four times higher than conventional rice varieties. The economic viability of most other varieties remains unknown as they have not yet been tested in the market. These findings present crucial insights for researchers, policymakers, development practitioners, and the private sector to further explore, act upon, facilitate, and invest in the untapped potential, aiming to break the vicious cycle and ensure increased income, reduced migration, and conservation of ecological and environmental resources.
Spatio-temporal Analysis of Land Surface Temperature in West Tripura District, India
Authors: Debbarma Jimmi , Chakma Richa
Published: March 2024

Land surface temperature is a crucial factor that affects many ecological and environmental processes, such as the urban heat island effect, the health of the plants, and the effects of climate change. An increase in global temperature and erratic rainfall has been observed as a result of the weather's change during the recent past. Understanding the Spatio-temporal change of the land surface temperature can provide us with insights for sustainable land use management, urban planning, and also aid in planning and formulating plans to combat climate change. The present study area is the most populated district in Tripura and has experienced some of the fastest transformation in urban infrastructure. This study's objective was to investigate at how the land surface temperature (LST) varies across space and time in the West Tripura District. Landsat- 8 OLI and Landsat-5 ETM was the source of data to investigate the purpose of the study. The LST data was derived from thermal bands of the satellite imagery using remote sensing algorithm in ArcGIS and NDVI was computed using NIR and RED bands. Upto the year 2020, steady rise in built up areas was observed with a decline in land cover until 2010. However, the year 2020 witnessed an increase in vegetation cover. Similarly, the land surface temperature revealed higher values till 2010 may be attributed to loss of vegetation cover and subsequent decrease in values of land surface temperature after 2010 may be attributed to afforestation and growing popularity of plantation schemes.
Morphological and Biochemical Characterization of Phyllosphere Bacteria
Authors: Lakkannavar Chaitra , Swamy Mahadeva , Yallappa  , Gouda Pampana , Ramesh Y. M.  , Rao Satyanarayan
Published: March 2024

Phyllosphere bacteria, residing on the surfaces of plant leaves, play crucial roles in plant health and environmental processes. This study aimed to investigate the morphological and biochemical traits of the isolated phyllosphere bacteria from cereal plant species. Isolates were collected from the leaves of different cereal plants and subjected to morphological and biochemical assays were performed to characterize their metabolic capabilities. Results revealed a diverse array of morphotypes, including cocci and bacilli, indicating the presence of varied bacterial species in the phyllosphere. Furthermore, a set of biochemical analyses highlighted metabolic versatility among isolates, with varying abilities to utilize different carbon sources and produce enzymes. These findings underscore the heterogeneity and metabolic diversity of phyllosphere bacteria, suggesting their potential roles in nutrient cycling, plant growth promotion and disease suppression. Further exploration of these characteristics could elucidate the mechanisms underlying plant-microbe interactions in the phyllosphere and inform strategies for sustainable agriculture and environmental management.
Ergenlerde Öfke ve Öfkeyi İfade Etme Biçimlerinin Ebeveynlik Stilleri, Duygusal Özerklik ve Bağlanma Özellikleriyle İlişkisinin İncelenmesi
Authors: DAĞLI Fatma Betül , DEVECİ ŞİRİN Hatice
Published: March 2024

Bu araştırmanın amacı ergenlik dönemindeki bireylerin sürekli öfke ve öfkeyi ifade etme biçimlerinin duygusal özerklik düzeyleri, bağlanma yönelimleri ve ebeveynlerinin çocuk yetiştirme stilleriyle ilişki olup olmadığını incelemektir. Araştırmanın çalışma grubunu 370 kadın, 308 erkek olmak üzere 678 kişi oluşturmaktadır. Uygulamaya katılan ergenlerin kişisel bilgilerini elde edebilmek için Kişisel Bilgi Formu, sürekli öfke ve öfke ifade tarzlarını belirlemek için Sürekli Öfke ve Öfke İfade Tarz Ölçeği, duygusal özerklik düzeylerini belirlemek için Duygusal Özerklik Ölçeği, ebeveynlerinin çocuk yetiştirme stillerini belirlemek için Çocuk Yetiştirme Tutumları Ölçeği ve bağlanma yönelimlerini belirlemek için Yakın İlişkilerde Yaşantılar Envanteri – İlişki Yapıları kullanılmıştır. Araştırma bulgularına göre anne babaya bağlanma yönelimi, ebeveynlik stilleri ve duygusal özerklik alt boyutları birlikte Öfke ve öfke ifade tarzının anlamlı yordayıcılarıdır. Buna göre sürekli öfkedeki toplam varyansın ortalama %12’si, içe yönlendirilmiş öfkedeki toplam varyansın ortalama %13’ü, dışsallaştırılmış öfkedeki toplam varyansın ortalama %14’ü ve öfke kontrolü toplam varyansın ortalama %14’ü bağımsız değişkenler tarafından açıklanmaktadır. Bu araştırma bulguları sonucunda ergenlik döneminde öfke ve öfke ifade tarzının açıklanmasında ebeveyn-çocuk etkileşimi ile ilgili dinamiklerin ve duygusal özerkliğin rolünün önemli olduğu görülmektedir. Araştırmanın bulguları ilgili literatür çerçevesinde tartışılarak araştırmacı ve alan uzmanlarına öneriler sunulmuştur.
A Family of Far‐Infrared‐Transmitting Glasses in the Ga–Ge–Te System for Space Applications
Authors: Danto S. , Houizot P. , Boussard‐Pledel C. , Zhang X.‐H. , Smektala F. , Lucas J.
Published: August 2006

Conditions of formation of bulk tellurium chalcogenide glasses, containing 70–80 at % Te associated to Ga and Ge are described. The characteristic temperatures are measured: the glass‐transition temperature, Tg, is situated in the range 140–185 °C and the difference Tx – Tg, where Tx is the onset crystallization temperature, is in the range 76–113 °C. Moreover, the optical transmission window is exceptional, ranging from 1.99 μm in the bandgap up to 28 μm in the phonon region.

Developed within the framework of requirements for the Darwin mission (a search for and study of extrasolar planets), feasibility of infrared optical fibers formed from these glasses is studied. Drawing experiments are conducted with the glass Ga2‐Ge3Te15, which possesses the maximum Tx – Tg, and a first optical fiber is presented.
Parameters Influencing Charge Separation in Solid‐State Dye‐Sensitized Solar Cells Using Novel Hole Conductors
Authors: Kroeze J. E. , Hirata N. , Schmidt‐Mende L. , Orizu C. , Ogier S. D. , Carr K. , Grätzel M. , Durrant J. R.
Published: August 2006

Solid‐state dye‐sensitized solar cells employing a solid organic hole‐transport material (HTM) are currently under intensive investigation, since they offer a number of practical advantages over liquid‐electrolyte junction devices. Of particular importance to the design of such devices is the control of interfacial charge transfer. In this paper, the factors that determine the yield of hole transfer at the dye/HTM interface and its correlation with solid‐state‐cell performance are identified. To this end, a series of novel triarylamine type oligomers, varying in molecular weight and mobility, are studied. Transient absorption spectroscopy is used to determine hole‐transfer yields and pore‐penetration characteristics. No correlation between hole mobility and cell performance is observed. However, it is found that the photocurrent is directly proportional to the hole‐transfer yield. This hole‐transfer yield depends on the extent of pore penetration in the dye‐sensitized film as well as on the thermodynamic driving force ΔGdye–HTM for interfacial charge transfer. Future design of alternative solid‐state HTMs should focus on the optimization of pore‐filling properties and the control of interfacial energetics rather than on increasing material hole mobilities.
Fluorescent Liquid‐Crystal Gels with Electrically Switchable Photoluminescence
Authors: Tong X. , Zhao Y. , An B.‐K. , Park S. Y.
Published: August 2006

Fluorescent self‐assembled liquid gels have been prepared for the first time through the use of a gelator showing aggregation‐induced enhanced emission. The photoluminescence, arising from the fibrous aggregates of the gelator, can be repeatedly switched by an electric field. Modulating the excitation light through electric‐field‐induced liquid‐crystal orientation offers new ways to achieve and explore electrically controllable photoluminescence.
Diamine modification of P84 polyimide membranes for pervaporation dehydration of isopropanol
Authors: Qiao Xiangyi , Chung Tai‐Shung
Published: August 2006

The effectiveness of chemical crosslinking modification of P84 copolyimide membranes using diamine compounds for pervaporation dehydration has been investigated, and the scheme to enhance separation performance of asymmetric polyimide membranes has been developed. Two diamine crosslinking agents, p‐xylenediamine and ethylenediamine (EDA), were used in this study for both dense and asymmetric P84 membranes. Experimental results suggest that the crosslinking reaction induced by EDA is much faster than that by p‐xylenediamine because the former has a smaller and linear structure than that of the latter. However, membranes crosslinked by p‐xylenediamine are thermally more stable than those by EDA. Membranes modified by p‐xylenediamine or EDA have increased hydrophilicity. An increase in the degree of crosslinking reaction initially results in an increase in separation factor with the compensation of lower flux for pervaporation dehydration of isopropanol (IPA). However, a further increase in the degree of crosslinking reaction may swell up the polymeric chains because of the hydrophilic nature of these diamine compounds, thus resulting in low separation performance. It is found that post treatment after crosslinking reaction can significantly enhance as well as tailor membrane performance because of the formation of charge transfer complexes (CTCs) and the enhanced degree of crosslinking reaction. A low‐temperature heat treatment may develop pervaporation membranes with high flux and medium separation factor, whereas a high‐temperature heat treatment may produce membranes with high separation factor with medium flux. © 2006 American Institute of Chemical Engineers AIChE J, 2006
Hospitalization rates and costs of care of patients with sickle‐cell anemia in the state of Maryland in the era of hydroxyurea
Authors: Lanzkron Sophie , Haywood Carlton , Segal Jodi B. , Dover George J.
Published: August 2006

The multicenter study of hydroxyurea (MSH) in sickle‐cell anemia (SCA) demonstrated that patients treated with hydroxyurea (HU) had a 44% decrease in hospitalizations when compared with those taking placebo. A subsequent study looking at the cost‐effectiveness of HU showed that decreased hospitalizations for painful crisis accounted for the majority of cost savings in those taking HU. The purpose of this study was to examine whether the expected decrease in hospital utilization occurred after the approval of HU in Maryland. We used data collected by the Maryland Health Services Cost Review Commission to obtain SCA discharge data for Maryland from FY1995 through FY2003. We also reviewed the inpatient and outpatient charts of all adults with SCA admitted to a large university hospital during 2003. Hospitalization rates for adults with SCA in Maryland have increased significantly since approval of HU. While the total costs of inpatient care in Maryland are estimated to have increased by 31% above inflation from 1995 to 2003, the costs of inpatient care for adult SCA patients has increased by almost 60% above inflation. By comparison, there has been no significant increase in the pediatric hospitalization rate. We found that 70% of patients in one hospital who were appropriate candidates for HU were not taking the medication. Hospital utilization among adults with SCA has increased significantly. There are likely many factors that have played a role in this increase. One factor that appears to be involved is the underutilization of HU. Am. J. Hematol., 2006. © 2006 Wiley‐Liss, Inc.
Identification of JAK2V617F in patients with polycythemia is highly correlated with conventional criteria for diagnosis of polycythemia vera
Authors: Ganly Peter , Hanrahan Vickie , Baker Bart , Romeril Ken
Published: August 2006

One hundred and forty four patients with a clinical indication of suspected polycythemia vera (PV), essential thrombocythemia, or idiopathic myelofibrosis were screened for JAK2V617F and the mutation frequency was 47, 51, and 50%, respectively. Previous investigations enabled 42 of 66 patients with suspected PV to be definitively diagnosed either as PV according to WHO criteria or to have this diagnosis excluded. Ninety‐six percent of those with PV were JAK2V617F, whereas all patients without PV did not have the mutation. Early screening of suspected PV patients for JAK2V617F rapidly identifies nearly all those with PV without invasive or less specific conventional investigations. Am. J. Hematol., 2006. © 2006 Wiley‐Liss, Inc.
Posttraumatic stress disorder in children affected by sickle‐cell disease and their parents
Authors: Hofmann Michel , de Montalembert Mariane , Beauquier‐Maccotta Bérengère , de Villartay Philippe , Golse Bernard
Published: August 2006

Children affected with sickle‐cell disease experience painful crises that may be life threatening, or felt as if they were. We evaluated by semistructured interviews and questionnaires the presence of posttraumatic stress disorder in 11 children affected by sickle‐cell disease and having suffered at least one hospitalization for a painful crisis, and in their parents (10 mothers, 1 father). Three children (27%) and four parents (40%) were diagnosed with the disorder. It was not correlated to the disease severity but, in parents, to a feeling of powerlessness over the child's illness (P = 0.04). Am. J. Hematol., 2006, © 2006 Wiley‐Liss, Inc.
Makrocyclisierung durch Ringschlussmetathese bei der Totalsynthese von Naturstoffen: Reaktionsbedingungen und Grenzen
Authors: Gradillas Ana , Pérez‐Castells Javier
Published: August 2006

Der Aufbau von Makrocyclen durch Ringschlussmetathese (RCM) ist oft eine Schlüsselstufe bei der Synthese von Naturstoffen mit großen Ringen. Diese Reaktion bietet sich an wegen ihrer hohen Toleranz für funktionelle Gruppen sowie der Möglichkeit zu nachfolgenden Umwandlungen. Dabei ist die Wahl geeigneter Reaktionsbedingungen für den Erfolg der Synthese entscheidend. Im folgenden Aufsatz fassen wir Arbeiten zusammen, die sich mit der Entwicklung effizienter RCM‐Reaktionen im Rahmen der Totalsynthese makrocyclischer Naturstoffe befassen. Dies soll helfen, bei zukünftigen Synthesen die zeitraubende Phase der Optimierung der Reaktionsbedingungen zu reduzieren.
Cover Picture: Luminescent One‐Dimensional Nanoscale Materials with PtII⋅⋅⋅PtII Interactions (Angew. Chem. Int. Ed. 34/2006)
Authors: Sun Yinghui , Ye Kaiqi , Zhang Hongyu , Zhang Junhu , Zhao Lan , Li Bao , Yang Guangdi , Yang Bai , Wang Yue , Lai Siu‐Wai , Che Chi‐Ming
Published: August 2006

Platinum(II)‐to‐platinum(II) interactions mediate and direct the formation of micro‐ and nanometer‐scale molecular wires of [Pt(CNtBu)2(CN)2]. The cover picture depicts models and microscopy images of the wires. Y. Wang, C.‐M. Che, and co‐workers describe in their Communication on page 5610 ff. the formation and photophysical properties of these photoluminescent molecular wires. An X‐ray crystallographic study provides a structural basis for rationalizing the photoluminescent responses.
A Posterior Tale
Authors: Korn Edward L. , Freidlin Boris
Published: August 2006

A vignette is presented that naively suggests that the posterior distribution of a parameter may not always contain everything that is needed for inference about that parameter. The resolution of this apparent paradox is discussed as well as its relation to real‐life problems involving data monitoring of clinical trials. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Modelling Forest Dynamics: A Perspective from Point Process Methods
Authors: Comas Carlos , Mateu Jorge
Published: August 2006

This paper reviews the main applications of (marked) point process theory in forestry including functions to analyse spatial variability and the main (marked) point process models. Although correlation functions do describe spatial variability at distinct range of scale, they are clearly restricted to the analysis of few dominant species since they are based on pairwise analysis. This has over‐simplified the spatial analysis of complex forest dynamics involving “large” number of species. Moreover, although process models can reproduce, to some extent, real forest spatial patterns of trees, the biological forest‐ecological interpretation of the resulting spatial structures is difficult since these models usually lack of biological realism. This problem gains in strength as usually most of these point process models are defined in terms of purely spatial relationships, though in real life, forest develop through time.

We thus aim to discuss the applicability of such formulations to analyse and simulate “real” forest dynamics and unwrap their shortcomes. We present a unified approach of modern spatially explicit forest growth models. Finally, we focus on a continuous space‐time stochastic process as an alternative approach to generate marked point patterns evolving through space and time. (© 2007 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Staurosporine induces tyrosine phosphorylation in Dictyostelium discoideum proteins
Authors: Andrioli Luiz Paulo , Souza Glaucia Mendes , da Silva Aline Maria
Published: August 2006

The treatment of cells with staurosporine results in inhibition and less frequently activation of protein kinases, in a cell‐type specific manner. In the social amoeba Dictyostelium discoideum, staurosporine induces marked changes in cell morphology affecting growth and development. Here we describe that incubation of D. discoideum growing or starved cells with staurosporine results in a rapid and unexpected tyrosine phosphorylation on two polypeptides of ∼64 and ∼62 kDa. These proteins emerge as novel substrates for tyrosine phosphorylation opening up new perspectives for the study of cell signalling in D. discoideum. Copyright © 2006 John Wiley & Sons, Ltd.
Characterization of Peroxide‐Bound Heme Species Generated in the Reaction of Thermally Tolerant Cytochrome c552 with Hydrogen Peroxide
Authors: Ichikawa Yusuke , Nakajima Hiroshi , Watanabe Yoshihito
Published: August 2006

Peroxide‐bound heme species have been considered difficult to detect under physiological conditions because of their intrinsically transient properties. Cytochrome c552 (cyt c552), from Thermus thermophirus HB8, bearing a mutation to an alanine at Met69 (M69A) reacts with hydrogen peroxide (H2O2) to generate a detectable hydroperoxo‐ferric heme ([Fe3+OOH]) species at ambient temperature. EPR measurements during appropriate reaction periods reveal that the [Fe3+OOH] species is in a preequilibrium state between the resting form of the cyt c552 variant and a subsequent intermediate, compound II with a protein radical. Addition of ascorbic acid to the reaction mixture of the cyt c552 variant and H2O2 does not affect the formation of the [Fe3+OOH] species,a result suggesting that the species is incompetent for the oxidation of even an oxidatively fragile substrate such as ascorbic acid. Another variant bearing an additional mutation to aspartic acid at Val49 (V49D/M69A) reveals that a highly hydrophobic heme cavity in cyt c552 accounts for the generation of the durable [Fe3+OOH] species. The less polar environment inside the cavity is expected to prevent H2O from approaching the cavity. This would suppress protonation of the distal oxygen atom of the [Fe3+OOH] species and retard subsequent dissociation of H2O from the OOH moiety.
The Consequences of Lysosomotropism on the Design of Selective Cathepsin K Inhibitors
Authors: Black W. Cameron , Percival M. David
Published: August 2006

Many drug candidates contain a basic functional group that results in lysosomotropism—the accumulation of drug in the acidic lysosomes of a cell. When evaluating inhibitors of lysosomal enzymes, such as the cathepsins, this physical property can have a dramatic impact on the functional selectivity of the test compounds. A basic P3 substituent in cathepsin K inhibitors provides a means of achieving potent and selective enzyme inhibition. To evaluate the whole‐cell selectivity of the basic cathepsin K inhibitor L‐006235, we identified the irreversible pan‐selective cathepsin probe BIL‐DMK and used it to design whole‐cell enzyme‐occupancy assays. These cell‐based assays showed a dramatic reduction in selectivity against cathepsins B, L, and S relative to the selectivities observed in enzyme assays. Two‐photon confocal fluorescence microscopy showed punctated subcellular localization of L‐006235, which colocalized with BODIPY‐labelled Lysotracker, consistent with compound lysosomotropism. To address this potential problem, a series of potent cathepsin K inhibitors was developed by replacing the P2P3 amide bond with a metabolically stable trifluoroethylamine moiety. X‐ray crystallography has identified the binding of this functional group to active‐site residues in cathepsin K. This modification resulted in increased potency and selectivity that allowed the removal of the basic P3 substituent. The resulting nonbasic inhibitor L‐873724 is a 0.2 nMinhibitor of cathepsin K with cathepsin B, L, and S potencies that were not shifted between purified enzyme and whole‐cell assays; thus indicating that this compound is not lysosomotropic. L‐873724 exhibits excellent pharmacokinetics and is orally active in a monkey model of osteoporosis at 3 mg kg−1q.d.
A multifaceted approach to the treatment of phantom limb pain using hypnosis
Authors: Bamford Candy
Published: August 2006

This study looks at the efficacy of a multifaceted approach to the relief of phantom limb pain. Using hypnosis, four therapeutic interventions are incorporated into this treatment: hypnotic analgesia; visualization and movement of an imaginary limb to facilitate the movement of the phantom limb; psychological therapy and self‐hypnosis. Twenty‐five amputees completed a course of hypnosis averaging six weekly sessions. All patients were taught self‐hypnosis and encouraged to continue this practice on a daily basis. The levels, duration and frequency of all pains were recorded before and after each session with a follow‐up postal questionnaire sent out six months after treatments were completed. Results showed a highly significant (p < 0.001) reduction in pain levels from baseline to post treatment. Pain levels showed some increase by the six month follow‐up questionnaire but were still significantly lower than the baseline. This study supports these combined hypnotic techniques as a treatment for phantom limb pain. Copyright © 2006 British Society of Experimental & Clinical Hypnosis. Published by John Wiley & Sons, Ltd.
A qualitative study of the experience of self‐hypnosis or Johrei in metastatic breast cancer using interpretative phenomenological analysis
Authors: Bennett Bryan M. , Laidlaw Tannis M. , Dwivedi Prabudha , Naito Akira , Gruzelier John H.
Published: August 2006

In this paper we explore the meaning and experience of living with breast cancer that had returned after conventional treatment. We focus on the process of learning and applying a specific psychological intervention to aid with the coping process. Of sixteen women who were randomized to self‐hypnosis training, Johrei training or a control wait‐list group, eight agreed to be interviewed. Interviews were recorded, transcribed and then analysed using interpretative phenomenological analysis. The major themes that conceptualized living with the return of breast cancer were self‐identity, self‐blame, social isolation and feelings of being constrained. The themes relating to psychological intervention were gaining a sense of control and empowerment, normalizing and re‐attribution, and a powerful military metaphor for dealing with the actual cancer. Copyright © 2006 British Society of Experimental & Clinical Hypnosis. Published by John Wiley & Sons, Ltd.
Pseudopolymorphism of Aliphatic Amine/4‐tert‐Butylcalix[4]arene Inclusion Compounds: Supramolecular Stabilization as a Route to Polar Clusters and Layers
Authors: Brown Philip O. , Udachin Konstantin A. , Enright Gary D. , Ripmeester John A.
Published: August 2006

4‐tert‐Butylcalix[4]arene (4tBC4A) is a versatile host capable of forming a variety of 1:1 and 2:1 inclusion compounds typically stabilized through van der Waals interactions. Preliminary studies in our group have demonstrated that inclusion of n‐butylamine in 4tBC4A results in a series of pseudopolymorphic inclusion compounds, including a new 3:1 inclusion motif. Using a combination of SCXRD, TGA, solid state NMR, and PXRD, we now elaborate upon the relationship between these pseudopolymorphs. We also demonstrate that larger amines demonstrate a similar degree of pseudopolymorphism, allowing for the production of customized materials using self‐assembly guided by competing weak forces. Finally, we comment on the structural implications of the relative dominance such forces in the formation of calixarene‐based supramolecular frameworks.
Diastereoselective Multicomponent Cyclizations of Fischer Carbene Complexes, Lithium Enolates, and Allylmagnesium Bromide Leading to Highly Substituted Five‐ and Six‐Membered Carbocycles
Authors: Barluenga José , Pérez‐Sánchez Iván , Suero Marcos G. , Rubio Eduardo , Flórez Josefa
Published: August 2006

The one‐pot sequential reaction of a chromium alkoxycarbene complex, a ketone or ester lithium enolate, and allylmagnesium bromide enabled the selective synthesis of novel diastereomerically pure pentasubstituted cyclopentanols or tetrasubstituted 1,4‐cyclohexanediols, depending on the degree of substitution at the Cβ position of the enolate anion. A few exceptions have been encountered in which tetrasubstituted cyclopentanols or pentasubstituted 1,4‐cyclohexanediols were selectively formed. The use of 2‐iodoethoxycarbene complexes gave access to 1,2,4‐cyclohexanetriols. These multicomponent‐coupling reactions involved the formation of lithium alkylpentacarbonylchromates as key intermediates, which further evolved through intramolecular processes, such as insertion of an alkene, CO insertion or addition to a carbonyl group, and, moreover, could be trapped in intermolecular reactions with different electrophiles and styrene. The substitution pattern of the alkylchromate carbon chain has been proposed to control the nature of the annulation process.
Mysterious Platinum Nitride.
Authors: von Appen Joerg , Lumey Marck‐Willem , Dronskowski Richard
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structures and Magnetic Properties of Alkali‐Metal Lanthanide Oxides A2LnO3 (A: Li, Na; Ln: Ce, Pr, Tb).
Authors: Hinatsu Yukio , Doi Yoshihiro
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Colloidal Upconverting NaYF4 Nanocrystals Doped with Er3+, Yb3+ and Tm3+, Yb3+ via Thermal Decomposition of Lanthanide Trifluoroacetate Precursors.
Authors: Boyer John‐Christopher , Vetrone Fiorenzo , Cuccia Louis A. , Capobianco John A.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of New Red Emitting Phosphors Based on Rare Earth Oxycarbonates.
Authors: Mayama Yuhei , Koyabu Kazuhiko , Masui Toshiyuki , Tamura Shinji , Imanaka Nobuhito
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Plasma Processing Approach to Molecular Surface Tailoring of Nanoparticles: Improved Photocatalytic Activity of TiO2.
Authors: Cho Jai , Denes Ferencz S. , Timmons Richard B.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Characterization and Structural Determination of a New Sodium Lanthanum Phosphate Thiosulfate, Na2La[PO4][S2O3].
Authors: Zhizhin Mikhail , Pounds Hillary A. , Spiridonov Felix M. , Komissarova Lydia N. , Dorhout Peter K.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cluster‐Type Basic Lanthanide Iodides [Ln6(μ6‐O)(μ3‐OH)8 (H2O)24]I8(H2O)8 (Ln: Nd, Eu, Tb, Dy).
Authors: Mudring Anja‐Verena , Timofte Tudor , Babai Arash
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Li9Nd2[PS4]5: A New Lithium Lanthanoid(III) Thiophosphate(V).
Authors: Komm Theresa , Schleid Thomas
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cs2Gd6N2Te7: The First Quaternary Nitride Telluride of the Lanthanides.
Authors: Lissner Falk , Schleid Thomas
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electrochemical Single Crystal Growth of Tb24O44 Microparticles.
Authors: Isota Shinya , Masui Toshiyuki , Tamura Shinji , Imanaka Nobuhito
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
β‐Homoamino Acids as Catalysts in Enantioselective Intra‐ and Intermolecular Aldol Reactions.
Authors: Limbach Michael
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Intramolecular Arylation of Aldehydes Promoted by Reaction with IPy2BF4/HBF4: Synthesis of Benzocyclic Ketones.
Authors: Barluenga Jose , Trincado Monica , Rubio Eduardo , Gonzalez Jose M.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Coupling Reaction of 3‐Bromo Benzo[b]furan, ‐thiophene and ‐selenophene 2‐Carboxaldehyde. Preparation of Tetracyclic Heteroaromatic Derivatives.
Authors: Kirsch Gilbert , Deprets Stephanie
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalyst‐Free Oxidation of Alcohols at Room Temperature Using Water as Solvent.
Authors: Lei Ziqiang , Yang Yaoxia , Bai Xiangzhen
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Amino Alcohols as Ligands for Nickel‐Catalyzed Suzuki Reactions of Unactivated Alkyl Halides, Including Secondary Alkyl Chlorides with Arylboronic Acids.
Authors: Gonzalez‐Bobes Francisco , Fu Gregory C.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heck Coupling with Nonactivated Alkenyl Tosylates and Phosphates: Examples of Effective 1,2‐Migrations of the Alkenyl Palladium(II) Intermediates.
Authors: Hansen Anders L. , Ebran Jean‐Philippe , Ahlquist Marten , Norrby Per‐Ola , Skrydstrup Troels
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Synthesis of Esters and Amides from Unprotected Hydroxyaromatic and ‐aliphatic Carboxylic Acids.
Authors: Katritzky Alan R. , Singh Sanjay K. , Cai Chunming , Bobrov Sergey
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective Oxidation of Oximes to Carbonyl Compounds Using N‐Bromo‐N‐benzoyl‐4‐toluenesulfonamide.
Authors: Khazaei Ardeshir , Manesh Abbas Amini
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
tert‐Butyl Ethers: Renaissance of an Alcohol Protecting Group. Facile Cleavage with Cerium(III) Chloride/Sodium Iodide.
Authors: Bartoli Giuseppe , Bosco Marcella , Carlone Armando , Locatelli Manuela , Marcantoni Enrico , Melchiorre Paolo , Sambri Letizia
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Na2S2O4‐Promoted Radical Addition Reaction of Perfluoroalkyl Iodides with Allenes and the Pd(0)‐Catalyzed Stereoselective Sonogashira Coupling Reaction of Addition Products with Propargyl Alcohol.
Authors: Ma Shengming , Ma Zhichao
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Diastereoselective Silyl‐Modified Sakurai Multicomponent Reaction.
Authors: Pospisil Jioi , Kumamoto Takuya , Marko Istvan E.
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rearrangement of Homoallylic Alcohols Induced by DAST.
Authors: Canova Sophie , Bellosta Veronique , Mignani Serge , Bigot Antony , Cossy Janine
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Study of Amidocarbonylation Reactions Catalyzed by Pd/HZSM‐5.
Authors: Yang Ke Wu , Jiang Xuan Zhen
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
DBU‐Catalyzed Cyanoacylation of Ketones with Acyl Cyanides.
Authors: Zhang Wen , Shi Min
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1,2‐Bis(diphenylphosphino)carborane as a Dual Mode Ligand for Both the Sonogashira Coupling and Hydride‐Transfer Steps in Palladium‐Catalyzed One‐Pot Synthesis of Allenes from Aryl Iodides.
Authors: Nakamura Hiroyuki , Kamakura Takaya , Onagi Shinya
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Free‐Radical Version of the Strecker Synthesis of α‐Aminoamides Promoted by Aqueous H2O2/TiCl3/HCONH2 System.
Authors: Cannella Rosalba , Clerici Angelo , Panzeri Walter , Pastori Nadia , Punta Carlo , Porta Ombretta
Published: August 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.