bluuebunny/crossref_metadata_2025 huggingface dataset:
Vegan Alternatives to Processed Cheese and Yogurt Launched in the European Market during 2020: A Nutritional Challenge?
Authors: Boukid Fatma , Lamri Melisa , Dar Basharat Nabi , Garron Marta , Castellari Massimo
Published: November 2021

Vegan alternatives to cheese (VAC) and yogurt (VAY) are fast-growing markets in Europe due to the increasing interest in plant-based alternatives to dairy products. This study aimed to take a closer look at the year 2020 and accordingly retrieved the nutritional information of dairy cheese and yogurt and their vegan counterparts for comparison. It was found that VAY (n = 182) provide more energy, total fats, and carbohydrates than dairy yogurt (n = 86), while saturated fatty acids (SFAs), sugars, and salt were not different between the two categories. Compared to dairy products (25.6%), 72.9% of the alternative products were declared low/no/reduced allergen, hence providing a larger spectrum of products to respond to consumers’ requirements. VAC (n = 114) showed high versatility of form compared to dairy (n = 115). Nutritionally, VAC have higher total fats, SFAs, and carbohydrates, but lower protein, salt, and sugar than dairy cheese. Food developers will continue to look for clean label solutions to improve the nutritional values of vegan products through the incorporation of natural ingredients, besides enhancing their taste and texture to appeal to flexitarians.
An Assessment of Selected Nutritional, Bioactive, Thermal and Technological Properties of Brown and Red Irish Seaweed Species
Authors: Mohammed Halimah O. , O’Grady Michael N. , O’Sullivan Maurice G. , Hamill Ruth M. , Kilcawley Kieran N. , Kerry Joseph P.
Published: November 2021

Irish edible brown (Himanthalia elongata—sea spaghetti, Alaria esculenta—Irish wakame) and red seaweeds (Palmaria palmata—dulse, Porphyra umbilicalis—nori) were assessed for nutritional (proximate composition; salt; pH; amino acid; mineral and dietary fibre contents); bioactive (total phenolic content (TPC) and in vitro antioxidant activity (DPPH and FRAP)); thermal (thermogravimetric analysis (TGA)); and technological (water holding capacity (WHC), oil holding capacity (OHC) and swelling capacity (SC)) properties. Red seaweeds had higher (p < 0.05) protein levels, whereas brown seaweeds possessed higher (p < 0.05) moisture, ash, insoluble and total dietary fibre contents. Nori had the lowest (p < 0.05) salt level. Seaweed fat levels ranged from 1 to 2% DW. Aspartic and glutamic acids were the most abundant amino acids. The total amino acid (TAA) content ranged from 4.44 to 31.80%. Seaweeds contained numerous macro (e.g., Na) and trace minerals. The TPC, DPPH and FRAP activities followed the order: sea spaghetti ≥ nori > Irish wakame > dulse (p < 0.05). TGA indicated maximum weight loss at 250 °C. Dulse had the lowest (p < 0.05) WHC and SC properties. Dulse and nori had higher (p < 0.05) OHC than the brown seaweeds. Results demonstrate the potential of seaweeds as functional food product ingredients.
Valorization of Rose Hip (Rosa canina) Puree Co-Product in Enriched Corn Extrudates
Authors: Igual Marta , Chiş Maria Simona , Păucean Adriana , Vodnar Dan Cristian , Muste Sevastița , Man Simona , Martínez-Monzó Javier , García-Segovia Purificación
Published: November 2021

Serious issues and challenges of the world’s population are represented by dwindling natural food resources and the scale-up of sustainable food manufacturing. Therefore, the valorization of co-products from the food industry represents new methods for food development. The principal goal of the study was to capitalize rose hip (Rosa canina) co-product powder in extrudates, highlighting its influence on extrusion parameters, physicochemical, and nutritional characteristics. The water absorption index, swelling index, and hygroscopicity increased with the rose hip co-product addition. Furthermore, water solubility index, expansion index, porosity, image parameters (area and perimeter) of the extrudates decreased. Lycopene, β-Carotene, Zea-esters, and lutein were the main carotenoids identified in the extrudates; whereas Catechin, Di-gallic acid, Procyanidin dimmer 1, Procyanidin dimmer 2, and Isorhamnetin-glucuronide were the main flavonoids. Strong Pearson correlations were identified between carotenoids, total flavonoids, vitamin C, total folate, and antioxidant activity. Valorization of the Rosa canina powder co-product led to value-added products—corn extrudates—rich in bioactive compounds.
A Novel Analytical Approach for the Solution of Fractional-Order Diffusion-Wave Equations
Authors: Mustafa Saima , Hajira  , Khan Hassan , Shah Rasool , Masood Saadia
Published: November 2021

In the present note, a new modification of the Adomian decomposition method is developed for the solution of fractional-order diffusion-wave equations with initial and boundary value Problems. The derivatives are described in the Caputo sense. The generalized formulation of the present technique is discussed to provide an easy way of understanding. In this context, some numerical examples of fractional-order diffusion-wave equations are solved by the suggested technique. It is investigated that the solution of fractional-order diffusion-wave equations can easily be handled by using the present technique. Moreover, a graphical representation was made for the solution of three illustrative examples. The solution-graphs are presented for integer and fractional order problems. It was found that the derived and exact results are in good agreement of integer-order problems. The convergence of fractional-order solution is the focus point of the present research work. The discussed technique is considered to be the best tool for the solution of fractional-order initial-boundary value problems in science and engineering.
Are Disks of Satellites Comprised of Tidal Dwarf Galaxies?
Authors: Bílek Michal , Thies Ingo , Kroupa Pavel , Famaey Benoit
Published: November 2021

It was found that satellites of nearby galaxies can form flattened co-rotating structures called disks of satellites or planes of satellites. Their existence is not expected by the current galaxy formation simulations in the standard dark matter-based cosmology. On the contrary, modified gravity offers a promising alternative: the objects in the disks of satellites are tidal dwarf galaxies, that is, small galaxies that form from tidal tails of interacting galaxies. After introducing the topic, we review here our work on simulating the formation of the disks of satellites of the Milky Way and Andromeda galaxies. The initial conditions of the simulation were tuned to reproduce the observed positions, velocities and disk orientations of the galaxies. The simulation showed that the galaxies had a close flyby 6.8 Gyr ago. One of the tidal tails produced by the Milky Way was captured by Andromeda. It formed a cloud of particles resembling the disk of satellites at Andromeda by its size, orientation, rotation and mass. A hint of a disk of satellites was formed at the Milky Way too. In addition, the encounter induced a warp in the disk of the simulated Milky Way that resembles the real warp by its magnitude and orientation. We present here, for the first time, the proper motions of the members of the disk of satellites of Andromeda predicted by our simulation. Finally, we point out some of the remaining open questions which this hypothesis, for the formation of disks of satellites, brings up.
Detectability of Continuous Gravitational Waves from Magnetically Deformed Neutron Stars
Authors: Soldateschi Jacopo , Bucciantini Niccolò
Published: November 2021

Neutron stars are known to contain extremely powerful magnetic fields. Their effect is to deform the shape of the star, leading to the potential emission of continuous gravitational waves. The magnetic deformation of neutron stars, however, depends on the geometry and strength of their internal magnetic field as well as on their composition, described by the equation of state. Unfortunately, both the configuration of the magnetic field and the equation of state of neutron stars are unknown, and assessing the detectability of continuous gravitational waves from neutron stars suffers from these uncertainties. Using our recent results relating the magnetic deformation of a neutron star to its mass and radius—based on models with realistic equations of state currently allowed by observational and nuclear physics constraints—and considering the Galactic pulsar population, we assess the detectability of continuous gravitational waves from pulsars in the galaxy by current and future gravitational waves detectors.
Regulating the Homogeneity of Thiol-Maleimide Michael-Type Addition-Based Hydrogels Using Amino Biomolecules
Authors: Guo Yu , Gu Jie , Jiang Yuxin , Zhou Yanyan , Zhu Zhenshu , Ma Tingting , Cheng Yuanqi , Ji Zongzhou , Jiao Yonghua , Xue Bin , Cao Yi
Published: November 2021

Poly(ethylene glycol) (PEG)-based synthetic hydrogels based on Michael-type addition reaction have been widely used for cell culture and tissue engineering. However, recent studies showed that these types of hydrogels were not homogenous as expected since micro domains generated due to the fast reaction kinetics. Here, we demonstrated a new kind of method to prepare homogenous poly(ethylene glycol) hydrogels based on Michael-type addition using the side chain amine-contained short peptides. By introducing such a kind of short peptides, the homogeneity of crosslinking and mechanical property of the hydrogels has been also significantly enhanced. The compressive mechanical and recovery properties of the homogeneous hydrogels prepared in the presence of side chain amine-contained short peptides were more reliable than those of inhomogeneous hydrogels while the excellent biocompatibility remained unchanged. Furthermore, the reaction rate and gelation kinetics of maleimide- and thiol-terminated PEG were proved to be significantly slowed down in the presence of the side chain amine-contained short peptides, thus leading to the improved homogeneity of the hydrogels. We anticipate that this new method can be widely applied to hydrogel preparation and modification based on Michael-type addition gelation.
Effectiveness and Safety of Botulinum Toxin Type A in Treatment of Restless Legs Syndrome: A Systematic Review and Meta-Analysis
Authors: Su Yu-Chi , Guo Yao-Hong , Liao Chung-Lun , Lin Yu-Ching
Published: November 2021

Our study aimed to investigate the effectiveness and safety of botulinum toxin type A in patients with restless legs syndrome. We searched electronic databases, including PubMed, Cochrane Library, and Web of Science, up to 12 June 2021, for published articles. We enrolled randomized controlled clinical trials and non-randomized controlled studies involving patients with restless legs syndrome who were treated with botulinum toxin. Quality assessment was performed using the Cochrane risk of bias tool and Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Studies. As for the results, we included four articles comprising 62 participants, two studies were randomized controlled trials. Improvement in International Restless Legs Syndrome Study Group (IRLSSG) rating scale was observed in three studies. Adverse events were temporary and self-limited. Meta-analyses were performed, including the two randomized controlled trials with 27 participants. Compared with placebo, botulinum toxin injection significantly reduced scores of IRLSSG rating scale (SMD, −0.819, 95% confidence interval [CI], −1.377 to −0.262). A total of 11.8% (95% CI, 0.7–72.4%) of patients reported at least one adverse event. In conclusion, botulinum toxin injection may relieve restless legs syndrome related symptoms. However, decisive conclusions cannot be drawn because of the small number of patients included in our meta-analysis. Large-scale, randomized controlled trials are warranted to discover the optimal dose, safety, and long-term effect of intervention with botulinum toxin type A for patients with restless legs syndrome.
Defining Potentially Inappropriate Prescriptions for Hypoglycaemic Agents to Improve Computerised Decision Support: A Study Protocol
Authors: Quindroit Paul , Baclet Nicolas , Gerard Erwin , Robert Laurine , Lemaitre Madleen , Gautier Sophie , Delannoy-Rousselière Chloé , Décaudin Bertrand , Vambergue Anne , Beuscart Jean-Baptiste
Published: November 2021

In France, around 5% of the general population are taking drug treatments for diabetes mellitus (mainly type 2 diabetes mellitus, T2DM). Although the management of T2DM has become more complex, most of these patients are managed by their general practitioner and not a diabetologist for their antidiabetics treatments; this increases the risk of potentially inappropriate prescriptions (PIPs) of hypoglycaemic agents (HAs). Inappropriate prescribing can be assessed by approaches that are implicit (expert judgement based) or explicit (criterion based). In a mixed, multistep process, we first systematically reviewed the published definitions of PIPs for HAs in patients with T2DM. The results will be used to create the first list of explicit definitions. Next, we will complete the definitions identified in the systematic review by conducting a qualitative study with two focus groups of experts in the prescription of HAs. Lastly, a Delphi survey will then be used to build consensus among participants; the results will be validated in consensus meetings. We developed a method for determining explicit definitions of PIPs for HAs in patients with T2DM. The resulting explicit definitions could be easily integrated into computerised decision support tools for the automated detection of PIPs.
Regulation Awareness and Experience of Additional Monitoring among Healthcare Professionals in Finland
Authors: Sandberg Andreas , Ehlers Pauliina , Torvinen Saku , Sandberg Heli , Sivén Mia
Published: November 2021

Background: Challenges in post-marketing adverse event reporting are generally recognized. To enhance reporting, the concept of additional monitoring was introduced in 2012. Additional monitoring aims to enhance reporting of adverse events (AE) for medicines for which the clinical evidence base is less well developed. Purpose: The purpose was to get a deeper understanding of the underlying reasons why additional monitoring has not increased AE reporting as much as initially hoped. We examined how healthcare professionals (HCPs) in Finland perceive additional monitoring, why they do or do not report AEs more readily for these medicines and how they interact with patients treated with additionally monitored medicines. Methods: An anonymous, open questionnaire was developed and made available online at the e-form portal of University of Helsinki. Physicians, nurses, and pharmacists were invited to complete the questionnaire via their respective trade or area unions. Content analysis of answers to open-ended questions was performed by two independent coders. Results: Pharmacists have the best understanding about additional monitoring but at the same time do not recognize their role in enhancing monitoring. Only 40% of HCPs working with patients knows always or often if a specific medicine is additionally monitored. Half (53%) of HCPs do not tell or tell only rarely patients about additional monitoring. 18% of HCPs reported having received additional monitoring training whereas 29% had received general AE reporting training. AE reporting was more common among HCPs who had received training. Conclusions: Additional monitoring awareness among HCPs and patients should be increased by organizing regular educational events and making additional monitoring more visible. Educational events should emphasize the significance additional monitoring has on patient safety and promote a reporting culture among HCPs.
Distinct Ground Reaction Forces in Gait between the Paretic and Non-Paretic Leg of Stroke Patients: A Paradigm for Innovative Physiotherapy Intervention
Authors: Kokolevich Zoe Mass , Biros Erik , Tirosh Oren , Reznik Jacqueline Elise
Published: November 2021

This case report study aims to identify the differences in the ground reaction forces (GRF) placed on the forefoot, hindfoot, and entire foot between the paretic and non-paretic legs in two stroke patients to identify potential targets for improved physiotherapy treatment. A digital gait analysis foot pressure insole was fitted inside the participants’ shoes to measure the percentage of body weight taken during the stance phase, and the vertical GRF of the two subjects are reported in this paper. Both patients presented noteworthy differences in gait parameters individually and between their paretic and non-paretic legs. The trend shows a decreased percentage of body weight on the paretic forefoot and hindfoot, although the percentage bodyweight placed on the entire foot remained similar in both feet. The gait patterns shown were highly individual and indicated that both legs were affected to some degree. These findings identify key motion targets for an improved physiotherapy treatment following a stroke, suggesting that physiotherapy treatment should be targeted and individually tailored and should include both extremities.
Physical Therapy Use and Associated Factors in Adults with and without Osteoarthritis—An Analysis of the Population-Based German Health Update Study
Authors: Sussmann Kim Elisa , Jacobs Hannes , Hoffmann Falk
Published: November 2021

Background: Physical therapy (PT) is recommended as first-line management for osteoarthritis (OA). The purpose of this study was to assess the PT use among adults with OA and those without (Non-OA) and subsequently identify associated factors among these populations. Methods: This cross-sectional study obtained national data from the population-based German Health Update (GEDA2014/2015-EHIS) study containing 24,016 participants aged 18 years and older. Analyses were stratified by sex, age, socioeconomic status (SES), residence, smoking behavior, body mass index, pain and general health. Multivariate regression analysis was conducted to evaluate factors associated with PT use within the past 12 months. Results: PT was used more frequently in the OA population compared with the Non-OA population (35.8% vs. 18.7%). In both populations, women, participants with high SES, residence in Eastern Germany, severe pain, poor general health and non-smokers received PT more frequently. Multivariate analysis confirmed these findings, in addition to people aged 80 years and older. The influence of SES was higher among OA participants. Conclusion: The underutilization of PT in OA patients (35.8%) was particularly evident among males, people with a low SES and those being older than 60 years, which aids to develop strategies increasing PT use towards guideline-oriented OA management.
Effects of Berry Thinning on the Physicochemical, Aromatic, and Sensory Properties of Shine Muscat Grapes
Authors: Choi Kyeong-Ok , Im Dongjun , Park Seo Jun , Lee Dong Hoon , Kim Su Jin , Hur Youn Young
Published: November 2021

The effects of the level of berry thinning (30% and 50% berry removal) on the quality and sensory properties of Shine Muscat grapes were investigated. As berry thinning increased, the total soluble solids content increased and titratable acidity decreased. Berry thinning increased berry size and cluster weight but caused no change in individual berry weight. Phenolic concentrations as measured by total phenolic, proanthocyanidin, and polymeric tannin concentrations tended to increase with an increase in berry thinning. Gas chromatographic analysis indicated that C6-compounds were the significant constituents of volatile alcohols and aldehydes; linalool was the most abundant monoterpene. Odor activity analysis indicated that (E)-2-hexen-1-ol, (E)-2-hexenal, 1-hexanal, (Z)-3-hexenal, (E)-β-damascenone, linalool, and (E)-linalool oxide were active odorants. Berry thinning increased the accumulation of linalool contributing to high sensory flavor scores in thinned berries. Furthermore, its oxidized derivative-linalool oxide-contributed to enhancing the Muscat flavor. In conclusion, berry thinning induced compositional changes in Shine Muscat grape berries by accelerating the ripening rate, contribution to improved sensory properties.
Tracer Dispersion through Karst Conduit: Assessment of Small-Scale Heterogeneity by Multi-Point Tracer Test and CFD Modeling
Authors: Deleu Romain , Frazao Sandra Soarez , Poulain Amaël , Rochez Gaëtan , Hallet Vincent
Published: November 2021

Tracer tests are widely used for characterizing hydrodynamics, from stream-scale to basin-wide scale. In karstic environments, the positioning of field fluorometers (or sampling) is mostly determined by the on-site configuration and setup difficulties. Most users are probably aware of the importance of this positioning for the relevance of data, and single-point tests are considered reliable. However, this importance is subjective to the user and the impact of positioning is not well quantified. This study aimed to quantify the spatial heterogeneity of tracer concentration through time in a karstic environment, and its impact on tracer test results and derived information on local hydrodynamics. Two approaches were considered: on-site tracing experiments in a karstic river, and Computational Fluid Dynamics (CFD) modeling of tracer dispersion through a discretized karst river channel. A comparison between on-site tracer breakthrough curves and CFD results was allowed by a thorough assessment of the river geometry. The results of on-site tracer tests showed significant heterogeneities of the breakthrough curve shape from fluorometers placed along a cross-section. CFD modeling of the tracer test through the associated discretized site geometry showed similar heterogeneity and was consistent with the positioning of on-site fluorometers, thus showing that geometry is a major contributor of the spatial heterogeneity of tracer concentration through time in karstic rivers.
Research Advances in the Analysis of Nitrate Pollution Sources in a Freshwater Environment Using δ15N-NO3− and δ18O-NO3−
Authors: Niu Chao , Zhai Tianlun , Zhang Qianqian , Wang Huiwei , Xiao Lele
Published: November 2021

Nitrate is usually the main pollution factor in the river water and groundwater environment because it has the characteristics of stable properties, high solubility and easy migration. In order to ensure the safety of water supply and effectively control nitrate pollution, it is very important to accurately identify the pollution sources of nitrate in freshwater environment. At present, as the most accurate source analysis method, isotope technology is widely used to identify the pollution sources of nitrate in water environment. However, the complexity of nitrate pollution sources and nitrogen migration and transformation in the water environment, coupled with the isotopic fractionation, has changed the nitrogen and oxygen isotopic values of nitrate in the initial water body, resulting in certain limitations in the application of this technology. This review systematically summarized the typical δ15N and δ18O-NO3− ranges of NO3− sources, described the progress in the application of isotope technique to identify nitrate pollution sources in water environment, analyzed the application of isotope technique in identifying the migration and transformation of nitrogen in water environment, and introduced the method of quantitative source apportionment. Lastly, we discussed the deficiency of isotope technique in nitrate pollution source identification and described the future development direction of the pollution source apportionment of nitrate in water environment.
Virtual Reality in the Treatment of Adults with Chronic Low Back Pain: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Authors: Brea-Gómez Beatriz , Torres-Sánchez Irene , Ortiz-Rubio Araceli , Calvache-Mateo Andrés , Cabrera-Martos Irene , López-López Laura , Valenza Marie Carmen
Published: November 2021

Virtual reality (VR) can present advantages in the treatment of chronic low back pain. The objective of this systematic review and meta-analysis was to analyze the effectiveness of VR in chronic low back pain. This review was designed according to PRISMA and registered in PROSPERO (CRD42020222129). Four databases (PubMed, Cinahl, Scopus, Web of Science) were searched up to August 2021. Inclusion criteria were defined following PICOS recommendations. Methodological quality was assessed with the Downs and Black scale and the risk of bias with the Cochrane Risk of Bias Assessment Tool. Fourteen studies were included in the systematic review and eleven in the meta-analysis. Significant differences were found in favor of VR compared to no VR in pain intensity postintervention (11 trials; n = 569; SMD = −1.92; 95% CI = −2.73, −1.11; p < 0.00001) and followup (4 trials; n = 240; SDM = −6.34; 95% CI = −9.12, −3.56; p < 0.00001); and kinesiophobia postintervention (3 trials; n = 192; MD = −8.96; 95% CI = −17.52, −0.40; p = 0.04) and followup (2 trials; n = 149; MD = −12.04; 95% CI = −20.58, −3.49; p = 0.006). No significant differences were found in disability. In conclusion, VR can significantly reduce pain intensity and kinesiophobia in patients with chronic low back pain after the intervention and at followup. However, high heterogeneity exists and can influence the consistency of the results.
Exploring Socio-Demographic Factors Affecting Psychological Symptoms in Humidifier Disinfectant Survivors
Authors: Ko Hye-Yun , Ryu Seung-Hun , Lee Min-Joo , Lee Hun-Ju , Kwon Soo-Young , Kim Seong-Mi , Lee Sang-Min
Published: November 2021

This study aimed to compare the psychological symptoms of humidifier disinfectant survivors to the general population and explore socio-demographic factors influencing survivors’ psychological symptoms. A one-way Multivariate Analysis of Covariance (MANCOVA) and a series of two-way MANCOVA were conducted with a sample of 228 humidifier disinfectant survivors and 228 controls. The results demonstrated that the survivor group displayed higher anxious/depressed symptoms, withdrawn symptoms, somatic complaints, thought problems, attention problems, aggressive behavior and rule-breaking behavior than the general group. Moreover, among the socio-demographic factors, the two-way interaction effects of group × family economic status and group × number of friends were found to be statistically significant. The limitations and implications of this study are discussed.
Revealing Distress and Perceived Stress among Dentists at the Outset of the COVID-19 Pandemic: A Cross-Sectional Factor Analytic Study
Authors: Serota Kenneth S. , Andó Bálint , Nagy Katalin , Kovács Ildikó
Published: November 2021

Dentists’ perceptions about the stressfulness of clinical practice are well-documented, but literature on perceived stress and psychological distress experienced during the COVID-19 pandemic is scarce. This study aims to explore the emotions and attitudes, and the socio-demographic, dental, and COVID-related factors that are associated with the emergence of perceived stress and psychological distress that have been experienced by dentists during the COVID-19 pandemic. General demographic and dental-related data, and specific questions measuring the potential factors regarding dental professionals’ concerns and opinions about their professional circumstances during the pandemic, were electronically collected from 182 dental practitioners. Exploratory and confirmatory factor analyses were used to assess whether dentists’ emotions and attitudes during the pandemic measure the same construct: psychological distress, while linear regression models were built on the exploration of the effects of COVID-related factors on perceived stress and psychological distress. Facets of impulsiveness, lack of interest in social connections, emotional disengagement, mood swings, and acknowledgment of emotional exhaustion due to the pandemic, were measurements of the same construct and manifested in a singular factor: psychological distress. Two aspects, the fear of aerosol propagation and insecurities of financial status, increased the likelihood of the emergence of heightened levels of perceived stress and distress, while years spent in dental practice and age seemed to be protective factors against perceived stress and distress.
Integrating Self-Report and Psychophysiological Measures in Waterpipe Tobacco Message Testing: A Novel Application of Multi-Attribute Decision Modeling
Authors: Stevens Elise M. , Villanti Andrea C. , Leshner Glenn , Wagener Theodore L. , Keller-Hamilton Brittney , Mays Darren
Published: November 2021

Background: Waterpipe (i.e., hookah) tobacco smoking (WTS) is one of the most prevalent types of smoking among young people, yet there is little public education communicating the risks of WTS to the population. Using self-report and psychophysiological measures, this study proposes an innovative message testing and data integration approach to choose optimal content for health communication messaging focusing on WTS. Methods: In a two-part study, we tested 12 WTS risk messages. Using crowdsourcing, participants (N = 713) rated WTS messages based on self-reported receptivity, engagement, attitudes, and negative emotions. In an in-lab study, participants (N = 120) viewed the 12 WTS risk messages while being monitored for heart rate and eye-tracking, and then completed a recognition task. Using a multi-attribute decision-making (MADM) model, we integrated data from these two methods with scenarios assigning different weights to the self-report and laboratory data to identify optimal messages. Results: We identified different optimal messages when differently weighting the importance of specific attributes or data collection method (self-report, laboratory). Across all scenarios, five messages consistently ranked in the top half: four addressed harms content, both alone and with themes regarding social use and flavors and one addiction alone message. Discussion: Results showed that the self-report and psychophysiological data did not always have the same ranking and differed based on weighting of the two methods. These findings highlight the need to formatively test messages using multiple methods and use an integrated approach when selecting content.
Multi-Angle Fusion-Based Safety Status Analysis of Construction Workers
Authors: Deng Hui , Ou Zhibin , Deng Yichuan
Published: November 2021

Hazardous accidents often happen in construction sites and bring fatal consequences, and therefore safety management has been a certain dilemma to construction managers for long time. Although computer vision technology has been used on construction sites to identify construction workers and track their movement trajectories for safety management, the detection effect is often influenced by limited coverage of single cameras and occlusion. A multi-angle fusion method applying SURF feature algorithm is proposed to coalesce the information processed by improved GMM (Gaussian Mixed Model) and HOG + SVM (Histogram of Oriented Gradient and Support Vector Machines), identifying the obscured workers and achieving a better detection effect with larger coverage. Workers are tracked in real-time, with their movement trajectory estimated by utilizing Kalman filters and safety status analyzed to offer a prior warning signal. Experimental studies are conducted for validation of the proposed framework for workers’ detection and trajectories estimation, whose result indicates that the framework is able to detect workers and predict their movement trajectories for safety forewarning.
Physical Restraint Use in Intensive Care Units: Exploring the Decision-Making Process and New Proposals. A Multimethod Study
Authors: Acevedo-Nuevo María , González-Gil María Teresa , Martin-Arribas María Concepción
Published: November 2021

Aim: The general aim of this study was to explore the decision-making process followed by Intensive Care Unit (ICU) health professionals with respect to physical restraint (PR) administration and management, along with the factors that influence it. Method: A qual-quant multimethod design was sequenced in two stages: an initial stage following a qualitative methodology; and second, quantitative with a predominant descriptive approach. The multicenter study was undertaken at 17 ICUs belonging to 11 public hospitals in the Madrid region (Spain) across the period 2015 through 2019. The qualitative stage was performed from an interpretative phenomenological perspective. A total of eight discussion groups (DG) were held, with the participation of 23 nurses, 12 patient care nursing assistants, and seven physicians. Intentional purposive sampling was carried out. DG were tape-recorded and transcribed. A thematic analysis of the latent content was performed. In the quantitative stage, we maintained a 96-h observation period at each ICU. Variables pertaining to general descriptive elements of each ICU, institutional pain-agitation/sedation-delirium (PAD) monitoring policies and elements linked to quality of PR use were recorded. A descriptive analysis was performed, and the relationship between the variables was analyzed. The level of significance was set at p ≤ 0.05. Findings: A total of 1070 patients were observed, amounting to a median prevalence of PR use of 19.11% (min: 0%–max: 44.44%). The differences observed between ICUs could be explained by a difference in restraint conceptualization. The various actors involved jointly build up a health care culture and a conceptualization of the terms “safety-risk”, which determine decision-making about the use of restraints at each ICU. These shared meanings are the germ of beliefs, values, and rituals which, in this case, determine the greater or lesser use of restraints. There were different profiles of PR use among the units studied: preventive restraints versus “Zero” restraints. The differences corresponded to aspects such as: systematic use of tools for assessment of PAD; interpretation of patient behavior; the decision-making process, the significance attributed to patient safety and restraints; and the feelings generated by PR use. The restraint–free model requires an approach to safety from a holistic perspective, with the involvement of all team members and the family.
Exploring Doctors’ Emerging Commitment to Rural and General Practice Roles over Their Early Career
Authors: McGrail Matthew , O’Sullivan Belinda , Gurney Tiana , Eley Diann , Kondalsamy-Chennakesavan Srinivas
Published: November 2021

Producing enough doctors working in general practice or rural locations, or both, remains a key global policy focus. However, there is a lack of evidence about doctors’ emerging commitment to these decisions. This study aimed to explore changes in the level of certainty about career interest in working in general practice and working rurally, as doctors pass through various early career stages. The participants were 775 eligible respondents to a 2019 survey of medical graduates of The University of Queensland from 2002–2018. Certainty levels of specialty choice were similar between GPs and specialists up until the beginning of registrar training. At that point, 65% of GPs compared with 80% of other specialists had strong certainty of their specialty field. Consistently (and significantly) less of those working rurally had strong certainty of the location where they wanted to practice medicine at each career time point. At the start of registrar training, a similar gap remained (strong certainty: 51% rural versus 63% metropolitan). This study provides new evidence that career intent certainty is more delayed for the cohort choosing general practice and rural practice than the other options. The low level of certainty in early career highlights the importance of regular positive experiences that help to promote the uptake of general practice and rural practice.
Implant Treatment by Guided Surgery Supporting Overdentures in Edentulous Mandible Patients
Authors: Velasco-Ortega Eugenio , Jiménez-Guerra Alvaro , Ortiz-Garcia Ivan , Garrido Nuno Matos , Moreno-Muñoz Jesús , Núñez-Márquez Enrique , Rondón-Romero José Luis , Cabanillas-Balsera Daniel , López-López José , Monsalve-Guil Loreto
Published: November 2021

Introduction: This study aimed to show the clinical outcomes of implants inserted by guided surgery supporting mandibular overdentures in edentulous patients. Patients and methods: Mandibular edentulous patients were diagnosed with an oral examination, cone-beam computerized tomography, and diagnostic casts for intermaxillary relations and treated with overdentures over two implants by guided surgery. After flapless surgery, implants were early loaded with an overdenture at 6 weeks. Results and discussion: Fourteen patients (nine females and five males) were treated with 28 implants. Four patients (28.6%) had a previous history of periodontitis. Five patients (35.7%) were smokers. Nine patients (64.3%) suffered from systemic diseases (i.e., diabetes, cardiovascular diseases). The clinical follow-up of the study was 44.7 ± 31.4 months. Clinical outcomes showed a global success of 100% of implants. Fourteen overdentures were placed in the patients over the implants. Mean marginal bone loss was 1.25 mm ± 0.95 mm. Four patients (28.6%) showed some kind of mechanical prosthodontic complications. Six implants (21.4%) were associated with peri-implantitis. Conclusions: This study indicates that treatment of mandibular edentulous patients with overdentures by guided surgery and early loading of implants placed appears to be a successful implant protocol.
Self-Disclosure and Non-Communication: Stigma Management in Third-Sector Transitional Employment
Authors: Niska Miira , Stevanovic Melisa , Weiste Elina , Ostrovskij Tommi , Valkeapää Taina , Lindholm Camilla
Published: November 2021

People who are recovering from a mental illness often have difficulties finding and maintaining employment. One of the main reasons for these difficulties is the negative label, or stigma, attached to mental illnesses. People who possess stigmatizing characteristics may use compensatory stigma management strategies to reduce discrimination. Due to mental illnesses’ invisible characteristics, information control is an important stigma management strategy. People can often choose whether they disclose or non-communicate their illness. Nevertheless, it might be difficult to decide when and to whom to disclose or non-communicate the stigma. Since stigma management is a dilemmatic process, workers in mental health services play an important role in informing their clients of when it is best to disclose or non-communicate their illness. In this article, we adopt the perspective of discursive social psychology to investigate how workers of one mental health service programme evaluate and construct self-disclosure and non-communication as stigma management strategies. We demonstrate how these workers recommend non-communication and formulate strict stipulations for self-disclosure. At the same time, they differentiate non-communication from lying or providing false information. The study contributes to an improved understanding of stigma management in contemporary mental health services.
Promoting Sports Practice in Persons with Hemophilia: A Survey of Clinicians’ Perspective
Authors: Lassandro Giuseppe , Accettura Domenico , Giordano Paola
Published: November 2021

Historically, people with hemophilia have been warned to avoid physical activities as a possible cause of bleeding; however, currently, sport is considered necessary, especially in the developmental age, for providing a good quality of life. A survey was proposed to a group of hematologists and sports physicians working in Puglia, Italy, to explore their approach to physical activities for their patients with hemophilia and to obtain suggestions about possible interventions to promote the access of patients to sports. The survey was answered by 6 hematologists and 15 sports physicians. In total, 71% (about six patients/year/physician) of patients with hemophilia seen by sports physicians asked for counseling about sports, and 67% (about five patients/year/physician) actually practiced sports. On the other hand, only 31% (about 16 patients/year/hematologist) of patients asked hematologists questions on sports, and only 16% (about seven patients/year/hematologist) of patients with hemophilia and that were followed-up by hematologists practiced sports. The sports most often recommended to patients with hemophilia by physicians included swimming, athletics, tennis, running and gymnastics. According to hematologists, physical activity was very efficient in improving the quality of life of patients; stability of joints; their psychological, social and musculoskeletal wellbeing; and in reducing the risk of bleedings. On the other hand, physical activity was considered less important in all these areas by sport physicians. In conclusion, answers to this survey suggested that sports could be promoted among hemophilic patients by increasing the sports physicians’ knowledge about hemophilia and their special role in this area. In addition, interviewed clinicians were of the opinion that increased awareness of specific guidelines and clinical practice protocols among both hematologists and sports physicians could be beneficial. Finally, answers suggested that access to fitness certification should be facilitated.
The 2019 Conference on Health and Active Transportation: Research Needs and Opportunities
Authors: Berrigan David , Dannenberg Andrew L. , Lee Michelle , Rodgers Kelly , Wojcik Janet R. , Wali Behram , Tribby Calvin P. , Buehler Ralph , Sallis James F. , Roberts Jennifer D. , Steedly Ann , Peng Binbin , Eisenberg Yochai , Rodriguez Daniel A.
Published: November 2021

Active transportation (AT) is widely viewed as an important target for increasing participation in aerobic physical activity and improving health, while simultaneously addressing pollution and climate change through reductions in motor vehicular emissions. In recent years, progress in increasing AT has stalled in some countries and, furthermore, the coronavirus (COVID-19) pandemic has created new AT opportunities while also exposing the barriers and health inequities related to AT for some populations. This paper describes the results of the December 2019 Conference on Health and Active Transportation (CHAT) which brought together leaders from the transportation and health disciplines. Attendees charted a course for the future around three themes: Reflecting on Innovative Practices, Building Strategic Institutional Relationships, and Identifying Research Needs and Opportunities. This paper focuses on conclusions of the Research Needs and Opportunities theme. We present a conceptual model derived from the conference sessions that considers how economic and systems analysis, evaluation of emerging technologies and policies, efforts to address inclusivity, disparities and equity along with renewed attention to messaging and communication could contribute to overcoming barriers to development and use of AT infrastructure. Specific research gaps concerning these themes are presented. We further discuss the relevance of these themes considering the pandemic. Renewed efforts at research, dissemination and implementation are needed to achieve the potential health and environmental benefits of AT and to preserve positive changes associated with the pandemic while mitigating negative ones.
Diversity Competency and Access to Healthcare in Hospitals in Croatia, Germany, Poland, and Slovenia
Authors: Doričić Robert , Orzechowski Marcin , Nowak Marianne , Tutić Grokša Ivana , Bielińska Katarzyna , Chowaniec Anna , Ramšak Mojca , Łuków Paweł , Muzur Amir , Zupanič-Slavec Zvonka , Steger Florian
Published: November 2021

Diversity competency is an approach for improving access to healthcare for members of minority groups. It includes a commitment to institutional policies and practices aimed at the improvement of the relationship between patients and healthcare professionals. The aim of this research is to investigate whether and how such a commitment is included in internal documents of hospitals in Croatia, Germany, Poland, and Slovenia. Using the methods of documentary research and thematic analysis we examined internal documents received from hospitals in these countries. In all four countries, the documents concentrate on general statements prohibiting discrimination with regard to healthcare provision. Specific regulations concerning ethnicity and culture focus on the issue of language barriers. With regard to religious practices, the documents from Croatia, Poland, and Slovenia focus on dominant religious groups. Observance of other religious practices and customs is rarely addressed. Healthcare needs of patients with non-heteronormative sexual orientation, intersexual, and transgender patients are explicitly addressed in only a few internal documents. Diversity competency policies are not comprehensively implemented in hospital internal regulations in hospitals under investigation. There is a need for the development and implementation of comprehensive policies in hospitals aiming at the specific needs of minority groups.
Solving Social Problems in Aging Rural Japanese Communities: The Development and Sustainability of the Osekkai Conference as a Social Prescribing during the COVID-19 Pandemic
Authors: Naito Yumi , Ohta Ryuichi , Sano Chiaki
Published: November 2021

Social prescribing is critical during the coronavirus disease 2019 (COVID-19) pandemic. Social prescribing refers to non-medical interventions related to culture and traditions; they are increasingly being proposed to address wider determinants of health as well as help patients improve health behaviors and manage their conditions effectively. Traditional and cultural behaviors in the community can be utilized for effective social prescribing. Due to the pandemic, social participation opportunities have decreased, resulting in the absence of Osekkai, a traditional Japanese behavior. A driver of Osekkai is the Osekkai conference; it is the model through which Osekkai is implemented in communities to bring resources and individuals together to address community needs. This research aims to clarify the Osekkai conference’s development process and how it can solve social problems, thereby leading to the creation of sustainable communities. We conducted semi-structured interviews with Osekkai conferences’ participants and organizers during the COVID-19 pandemic. We used thematic analysis to achieve the research aims. A total of 12 participants were interviewed. Five themes were developed from the thematic analysis: driver of the Osekkai conference’s development, trajectory of continuity, chain of Osekkai, changes in communities and participants, and sustainability of the conferences. This study showed how reviving traditional behaviors helps face initial difficulties. It described these increasing traditional behaviors in terms of social prescribing that changes the community’s and citizens’ social capital. Reviving traditional behaviors created new challenges and solutions during the pandemic.