bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembelajaran Al-Qur’an Metode Tilawati di Madrasah Ibtidaiyah Ma’arif Pagerwojo
Authors: Supriyanto Eko Budi , Nisak Nur Maslikhatun
Published: April 2024

Penelitian ini bertujuan untuk menginvestigasi dan mendeskripsikan implementasi Pembelajaran Al-Qur'an dengan Metode Tilawati di MI Ma'arif Pagerwojo. Metode Tilawati diterapkan dengan fokus pada pengulangan dan intonasi dalam membaca Al-Qur'an dengan harapan dapat meningkatkan pemahaman, penghafalan, dan keterampilan membaca peserta didik. Metode penelitian ini menggunakan pendekatan kualitatif deskriptif dengan teknik pengumpulan data melalui wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa MI Ma'arif Pagerwojo telah melaksanakan metode Tilawati dengan sungguh-sungguh. Guru-guru terlibat secara aktif dalam memberikan pengajaran, mengaplikasikan pengulangan, dan memberikan bimbingan terhadap intonasi pembacaan. Peserta didik menunjukkan respon positif dan antusiasme yang tinggi terhadap metode ini, meningkatkan motivasi mereka untuk membaca dan menghafal Al-Qur'an.  Meskipun demikian, terdapat beberapa tantangan seperti manajemen waktu dan bimbingan yang intensif untuk peserta didik tertentu. Hasil penelitian ini memberikan kontribusi penting terhadap pemahaman mengenai efektivitas metode Tilawati dalam konteks pembelajaran Al-Qur'an di MI Ma'arif Pagerwojo. Implikasi hasil penelitian ini diharapkan dapat memberikan panduan bagi pengembangan kurikulum dan metode pembelajaran Al-Qur'an yang lebih efektif di lembaga pendidikan Islam serupa.
Tata Kelola Sarana Serta Prasarana di Lembaga Pendidikan Dasar
Authors: Adelia Sisilia Ni Wayan Dina Natasya , Purnamaningsih Putu Eka
Published: April 2024

Pedoman nasional pendidikan ditujukan dalam rangka memastikan kualitas pendidikan nasional dengan tujuan dalam rangka mengembangkan kecerdasan masyarakat serta membuat karakter serta masyarakat yang beradab. Kriteria yang penting dalam rangka disediakan oleh lembaga pendidikan merupakan pedoman sarana serta prasarana. Sarana serta prasarana pendidikan memiliki peran penting sebagai sumber daya yang mendukung tahapan kegiatan belajar mengajar di lembaga pendidikan. Studi ini mengadopsi pendekatan deskriptif kualitatif dengan metode etnografi dalam rangka menganalisis manajemenatis tatakelola fasilitas dan infrastruktur di lembaga pendidikan dasar. Dalam rangka mewujudkan pedoman yang ditentukan, diperlukan tatakelola yang terstruktur serta terorganisir dengan baik. Tata kelola lembaga pendidikan adalah pelaksanaan prinsip-prinsip tatakelola dalam konteks pendidikan. Pengurusan komponen-komponen lembaga pendidikan, terutama tatakelola sarana serta prasarana, menjadi kunci utama dalam mewujudkan lingkungan lembaga pendidikan yang bersih, tertata dengan baik, serta menarik. Hal ini berkontribusi pada kondisi yang menyenangkan bagi seluruh anggota lembaga pendidikan, baik guru ataupun siswa. Tahapan tatakelola sarana serta prasarana mencakup langkah-langkah seperti perancangan, penyuplaian, perawatan, daftar barangasi, serta peniadaan.
Examining Reactions about COVID-19 Vaccines: A Systematic Review of Studies Utilizing Deep Learning for Sentiment Analysis
Authors: Saxena Ritwik Raj
Published: April 2024

Objective: The exponential growth of digital social platforms has not
only connected individuals globally but has also provided a platform for
users to freely express their experiences and viewpoints on topics
spanning from consumer products and services to broader societal matters
such as political issues. Within this expansive digital discourse, in
the recent years, one notably discussed subject has been the SARS-CoV-2
(COVID-19) vaccines. In this article, our focus is on investigating the
profound impact of neural networks in the analysis of sentiments
expressed by people concerning the introduction and utilization of these
vaccines. Background: Sentiment analysis, a critical facet of natural
language processing (NLP), is replete with intricate associations in the
linguistic landscape. Within its realms, many sophisticated
methodologies, such as machine learning algorithms, including neural
network architectures, are employed to decipher the intricate web of
semantic relationships embedded in textual data, which include, but are
not limited to, social media posts. From gathering business
intelligence, to market research and competitor analysis, examining
sentiments has found many practical uses. In the domain of COVID-19
vaccines, sentiment analysis has provided valuable insights into vaccine
hesitancy, vaccine adoption rates, and public trust in the governmental
setup and in the pharmaceutical industry. Methods: A systematic
literature review (meta-analysis) was carried out to quarry scientific
research on neural network-based analysis of sentiments about COVID-19
vaccines. Implementing a thorough search strategy, we isolated relevant
articles and methodically examined them to discern key insights that
contributed to our comprehension of the utility of neural networks in
analyzing public opinion regarding COVID-19 vaccines. Conclusion: Our
study provides insights affirming that neural networks have shown a
surpassing capacity to discern intricate patterns within vast textual
datasets. Their inherent ability to capture contextual nuances in
language has enabled a nuanced understanding of diverse sentiments about
COVID-19 vaccines. This has helped formulate strategies to alleviate
negative sentiments about the vaccines leading to higher vaccine
acceptance rates and management of the pandemic.
ANORMALIDADES PLACENTÁRIAS E SEU PAPEL NAS COMPLICAÇÕES OBSTÉTRICAS
Authors: Melo Ana Beatriz Oliveira de , Nascimento Maria Eduarda Bezerra do , Façanha Eliomara Brito , Baião Marcelo Augusto Pereira , Silva Andreza Balbino da , Oliveira Ozarlan Michel Pereira de , Rêgo Juliana Clemente do , Melo José Mário Delaiti de , Bispo Natália Beatriz Gomes , Rosa Victor Hugo Júlio de , Santos Miguel de Sousa , Silva Kelly Beatriz Zanforlin
Published: April 2024

As anormalidades placentárias representam uma preocupação significativa na prática obstétrica, pois podem desencadear uma série de complicações tanto para a mãe quanto para o feto durante a gravidez e o parto. Essas condições abrangem uma variedade de alterações na estrutura e função da placenta, incluindo descolamento, placenta prévia, insuficiência placentária e outras. Objetivo: Revisar as anormalidades placentárias e seu papel nas complicações obstétricas, fornecendo uma análise concisa das principais condições relacionadas à placenta que podem afetar a gravidez e o parto. Metodologia: Este estudo consistiu em uma revisão narrativa da literatura que investigou a relação entre o uso de substâncias durante a gravidez e o retardo do crescimento fetal. A pesquisa foi conduzida por meio de acesso online às bases de dados Documentação em Ciências da Saúde da América Latina e do Caribe (LILACS), Centro de Informação em Ciências da Saúde da América Latina e do Caribe (Bireme), Scientific Electronic Library Online (SCIELO) e Biblioteca Virtual em Saúde (BVS) durante o mês de março de 2024. Resultados e Discussão: As anormalidades placentárias desempenham um papel crucial nas complicações obstétricas, impactando tanto a saúde materna quanto fetal. Estudos mostram uma associação significativa entre descolamento de placenta, placenta prévia, insuficiência placentária e uma série de complicações, como parto prematuro, restrição de crescimento fetal, pré-eclâmpsia e até mesmo morte fetal intrauterina. A identificação precoce e o manejo adequado dessas condições são essenciais para reduzir os riscos para mãe e bebê. No entanto, o diagnóstico pode ser desafiador devido à variedade de apresentações clínicas e à falta de marcadores específicos para algumas anormalidades placentárias. Considerações Finais: As anormalidades placentárias representam um desafio significativo na prática obstétrica, contribuindo para complicações graves durante a gestação e o parto. A identificação precoce e o manejo adequado dessas condições são essenciais para reduzir os riscos para mãe e bebê. Embora ainda haja muito a ser compreendido sobre as causas e mecanismos subjacentes das anormalidades placentárias, é fundamental que os profissionais de saúde estejam atentos aos sinais e sintomas que podem indicar a presença dessas condições.
Atualizações e avanços no tratamento da insuficiência cardíaca
Authors: Adorno Rafael , Dias Santana Yasmmin , Maltez Santana Vieira Thales , Soares Silva João Victor , Lapa Malheiro Larissa , Carneiro de Aguiar Damasceno Gabriel , Nunes Assis Filipe , Oliveira Correia Murilo , Quiteiro Araujo Iasmin , Calasans dos Santos Souza Lyvua , Possidônio Ferreira Jose Fabio , De Barros Silva Roberto
Published: April 2024

Introdução: A insuficiência cardíaca é uma condição crônica que afeta milhões de pessoas em todo o mundo, caracterizada por sintomas como falta de ar, fadiga e inchaço nas pernas. Objetivo: Este estudo tem como objetivo analisar as atualizações e avanços no tratamento dessa condição. Metodologia: A metodologia empregada foi uma revisão de literatura com abordagem exploratória, consultando diversas bases de dados para identificar artigos relevantes publicados entre 2019 e 2024. Foram utilizados descritores específicos para conduzir as buscas, resultando em 112 artigos, dos quais 43 foram selecionados para uma avaliação mais detalhada, e 21 foram considerados particularmente relevantes. Resultados: O tratamento da insuficiência cardíaca envolve medidas farmacológicas e não farmacológicas, com destaque para inibidores da enzima conversora de angiotensina, bloqueadores do receptor de angiotensina II, betabloqueadores, terapias combinadas e monitoramento remoto. Atualizações recentes introduziram terapias promissoras, como o Sacubitril/Valsartan e os inibidores do cotransportador de sódio-glicose tipo 2, além de avanços em terapia gênica, células-tronco cardíacas e dispositivos de assistência circulatória avançada. Considerações Finais: A prevenção e o diagnóstico precoce são fundamentais para reduzir o ônus da insuficiência cardíaca, enquanto estímulos à pesquisa e investimentos em programas de investigação são essenciais para impulsionar descobertas científicas e traduzi-las em terapias viáveis. Uma abordagem holística, centrada no paciente, que inclui educação, suporte psicológico, modificação de estilo de vida e monitoramento contínuo, é crucial para melhorar resultados clínicos e fortalecer a parceria entre médicos e pacientes. Investir em pesquisa, prevenção e cuidados integrados pode levar a avanços significativos na luta contra a insuficiência cardíaca, beneficiando a saúde e a qualidade de vida em todo o mundo.
Incidência e Prevalência da Sífilis Congênita: Uma Análise Epidemiológica Comparativa entre as Regiões Norte e Sudeste do Brasil (2019-2023)
Authors: De Miranda Franco Costa Giovana , De Jesus Santos João Victor , Sousa Soares Maria Eduarda , Brissi Benito da Silva Samara , Carlos de Queiroz Johny
Published: April 2024

Este estudo visa preencher a lacuna na pesquisa brasileira sobre a incidência comparativa da sífilis congênita entre as regiões Sudeste e Norte. Pretende-se analisar quantitativamente a incidência da doença de 2019 a 2023 e descrever qualitativamente os fatores associados. Serão coletados dados sobre mães de crianças com sífilis congênita, como escolaridade, realização do pré-natal e idade materna, para uma análise abrangente. Trata-se de um estudo ecológico, observacional e temporal abrangendo a sífilis congênita nas regiões Norte e Sudeste do Brasil de 2019 a 2023. Os dados foram coletados do DATASUS em março de 2024. Serão realizadas análises quantitativas e qualitativas dos dados epidemiológicos e socioeconômicos.

Os casos de sífilis congênita nas regiões Norte e Sudeste, entre 2019 a 2023, revelaram uma redução significativa em ambas regiões. A distribuição dos casos variou conforme a escolaridade materna, com predominância de mães com ensino fundamental incompleto no Norte e de mães com ensino médio completo no Sudeste. Além disso, mostrou-se que, na região Norte, assim como na região Sudeste, um menor das mães não havia realizado o pré-natal. A faixa etária com a maioria dos casos foi entre 20 a 24 anos em ambas as regiões. Por fim, destacamos as diferenças expressivas em termos de densidade populacional entre as duas regiões do país, a fim de possibilitar uma análise mais objetiva.

Em resumo, a análise dos casos de sífilis congênita nas regiões Norte e Sudeste do Brasil destaca a necessidade de uma abordagem abrangente para lidar com o problema de saúde pública. A associação com a escolaridade materna e a realização do pré-natal ressalta a importância de estratégias preventivas amplas. É essencial uma abordagem coordenada entre diversos setores da sociedade para reduzir a incidência e prevalência da doença. Apesar das limitações do estudo, suas descobertas oferecem uma base sólida para orientar políticas de saúde e programas de prevenção.
Perfil epidemiológico das internações por Insuficiência Cardíaca no Brasil entre 2019 e 2023
Authors: Leal Soares Felipe , Bandeira Junqueira Mariana , Gonçalves da Silva Daniel , Rasnhe Ferreira Sampaio Kauan , Mendonça Raphael Braz João Pedro , Rocha Pinon Teixeira de Araújo Gabriel , Cirino Pereira Luciana , De Lima Carvalho Santiago Silveira Ana Beatriz , Eduardo Araújo da Silva Carlos , Andrade Alves Jade , Francisco de Paiva Neto Moniz , Santos de Souza Uilma
Published: April 2024

O presente estudo tem como objetivo analisar a epidemiologia das internações por insuficiência cardíaca (IC), no Brasil, nos últimos cinco anos. O estudo foi realizado através de um levantamento epidemiológico descritivo, quantitativo e retrospectivo das internações por IC no Brasil no período de 2019 a 2023. No Brasil foram registradas 941.576 internações por insuficiência cardíaca ocorridos entre 2019 e 2023. Dentre as Regiões, a Região do Sudeste apresentou os maiores índices de incidência, a maior taxa de mortalidade e maior letalidade. Dessa forma, notou-se que homens entre 70 e 79 anos e da etnia parda constituem o perfil mais acometido pela insuficiência cardíaca.
ALTERAÇÕES COGNITIVAS PÓS-INFECÇÃO PELO SARS-CoV-2
Authors: Cristina Gusmão Santiago  , Grace Silva Barbosa  , Aline Gonçalves Ferreira  , Rita de Cássia Caldeira Santos Goes  , Euvaíra Nunes de Aquino Fonseca  , Brunna Ariely Lopes de Souza  , Adriana Ramos da Rocha  , Davidson Gonçalves Soares  , Carla Rodrigues Pereira  , Ana Cecília Dias Batista  , Maria Esméria Neta  , João Paulo Almeida Souza  , Matheus Siega Nepomuceno  , Letícia Oliveira Silva  , Victor Guilherme Pereira  , Sarah de Moraes Alves
Published: April 2024

Objetivo: descrever as alterações cognitivas pós-infecção pelo SARS-CoV-2. Métodos: conduziu-se um estudo de revisão integrativa da literatura. Foram analisados artigos recuperados por meio das bases de dados secundários Biblioteca Virtual em Saúde (BVS), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Eletronic Library Online (Scielo) e Sistema Online de Busca e Análise de Literatura Médica (MEDLINE) a partir dos descritores covid-19, disfunção cognitiva, transtorno de memória. Considerou-se estudos publicados em português, inglês ou espanhol e que tratavam diretamente da temática objeto de estudo. Resultados: as alterações cognitivas mais prevalentes na síndrome pós- COVID-19 foram: dificuldade na velocidade de processamento; no funcionamento executivo; na fluência verbal fonêmica e semântica; na codificação e recordação de memória verbal; na aprendizagem; atenção sustentada; fadiga, memória de longo prazo espacial e verbal; funções executivas; aceleração de distúrbios neurodegenerativos. Conclusão: a presença de comprometimento cognitivo, mesmo em indivíduos com sintomas leves após infecção pelo SARS-COV-2. As principais alterações cognitivas após fase aguda da COVID podem configurar a COVID longa ou “long covid”.
Identification of spatial imbalances and risks of regional labor market development in Ukraine in the context of current destabilization processes
Authors: Vasyltsiv Taras H. , Levytska Olha O.
Published: April 2024

The article focuses on the problems of destabilization of the Ukrainian national economy and its regional markets in the context of the full-scale war. The key challenges of regional development in the short term as a result of their growing imbalances are identified, in particular the functioning of labor markets. The authors point out the long-term challenges to the development of regional labor markets and prove that the policy of their leveling should be based on strengthening competitiveness and enhancing convergence with the EU labor markets. The most critical trends in social stability in the regions of Ukraine during the war are characterized. The article presents statistical parameters of the registered labor market in the regions of Ukraine separately in terms of labor supply and separately in terms of labor demand in the pre-war period and during the war. The reasons for the low level of registered unemployment in the regions of Ukraine during the war are highlighted. The authors analyze the level of balance of regional labor markets and identify the main risks and threats to their functioning and development in the context of modern destabilization processes. Based on the analysis of regional aggregate demand (vacant and employed jobs) and aggregate supply (economically active population) in 2008, 2014, and 2021, the level of balance of the domestic labor market is calculated and assessed. Three types of labor-surplus regions are identified: (1) regions with a lag in socio-economic development and intensive demographic growth; (2) depressed regions, where the number of jobs stabilizes or decreases due to stagnation in the areas of specialization due to the exhaustion of raw materials or poor competitiveness of manufactured products; (3) regions with a deformed economic structure or monopoly position of enterprises and individual industries in the labor market, which leads to an imbalance of demographic or qualification nature. The prospects and priorities of the state policy of stabilizing the functioning and ensuring the development of regional labor markets in Ukraine are outlined.
ÉCLAIRAGE SUR L’ÉVOLUTION DE LA FABRIQUE DE LA DÉCISION À L’ÈRE DE L’IA
Authors: HIZAM MERIEM
Published: April 2024

Nous tentons d'explorer l'incidence de l'évolution technologique sur les prises de décision, en soulignant les avantages potentiels ainsi que les défis éthiques et pratiques associés à l'intégration de l'intelligence artificielle (IA) dans ces processus. Nous mettons en évidence la nécessité de comprendre les différentes étapes de la prise de décision et de clarifier le rôle de l'IA en fonction du contexte. Nous abordons également les perspectives de l'IA explicable pour atténuer les préoccupations liées à l'opacité et aux biais, et nous insistons sur l'importance de maintenir la responsabilité humaine malgré l'implication croissante de l'IA. Enfin nous proposons une grille de lecture pour une intégration judicieuse de l'IA dans les décisions organisationnelles, en soulignant l'importance de l’alignement stratégique des technologies pour un partenariat fructueux.
Efficient schema-less text-to-SQL conversion using large language models
Authors: Mellah Youssef , Kocaman Veysel , Ul Haq Hasham , Talby David
Published: April 2024

Large language models (LLMs) are increasingly being applied to several tasks including text-to-SQL (the process of converting natural language to SQL queries). While most studies revolve around training LLMs on large SQL corpora for better generalization and then perform prompt engineering during inference, we investigate the notion of training LLMs for schema-less prompting. In particular, our approach uses simple natural language questions as input without any additional knowledge about the database schema. By doing so, we demonstrate that smaller models paired with simpler prompts result in considerable performance improvement while generating SQL queries. Our model, based on the Flan-T5 architecture, achieves logical form accuracy (LFA) of 0.85 on the MIMICSQL dataset, significantly outperforming current state-of-the-art models such as Defog-SQL-Coder, GPT-3.5-Turbo, LLaMA-2-7B and GPT-4. This approach reduces the model size, lessening the amount of data and infrastructure cost required for training and serving, and improves the performance to enable the generation of much complex SQL queries.
Development and analysis of medical instruction-tuning for Japanese large language models
Authors: Sukeda Issey , Suzuki Masahiro , Sakaji Hiroki , Kodera Satoshi
Published: April 2024

In the ongoing wave of impact driven by large language models (LLMs) like ChatGPT, the adaptation of LLMs to the medical domain has emerged as a crucial research frontier. Since mainstream LLMs tend to be designed for general-purpose applications, constructing a medical LLM through domain adaptation is a huge challenge. While instruction-tuning, particularly based on low-rank adaptation (LoRA), has become a frequently employed strategy to fine-tune LLMs recently, its precise roles in domain adaptation remain unknown. Here, we investigated how LoRA-based instruction-tuning improves the performance of Japanese medical question-answering tasks by employing a multifaceted evaluation of multiple-choice questions, including scoring based on “Exact match” and “Gestalt distance” in addition to the conventional accuracy. Our findings suggest that LoRA-based instruction-tuning can partially incorporate domain-specific knowledge into LLMs, with larger models demonstrating more pronounced effects. Furthermore, our results underscore the potential of adapting English-centric models for Japanese applications in domain adaptation, while also highlighting the persisting limitations of Japanese-centric models. This initiative represents a pioneering effort in enabling medical institutions to fine-tune and operate models without relying on external services.
NON-TERRITORIAL AND TERRITORIAL OBJECTIVES OF CENTRAL AND EASTERN EUROPEAN ETHNOREGIONAL PARTIES
Authors: BARANYAI Nóra
Published: April 2024

In Central and Eastern Europe, even the post-socialist period has not made it easy for ethnic communities to exercise their linguistic and cultural rights, and territorial autonomy or self-government, as a risk to territorial integrity, has been granted only in exceptional cases. This paper focuses on the main objectives of ethnoregional parties to reorganise the power structure of the national political system. The study is based on an analysis of core documents from 92 parties in 15 Central and Eastern European countries, identifying and classifying the objectives set out in these documents. The results highlight the ethnoregional objectives in Central and Eastern Europe, including not only the cultural-linguistic dimension but also the need to change internal/external borders or the division of power within each state, highlighting the diversity and complexity of the problems and objectives underlying each category.
A Brief Review on Pharmacovigilance
Authors: KR Sribhavani
Published: April 2024

Clinical Research: Clinical research refers to the scientific investigation conducted to understand, prevent, diagnose, or treat human diseases and conditions. It involves the systematic study of individuals, often through clinical trials, to generate evidence-based knowledge that can advance medical understanding and improve patient care. Clinical research plays a crucial role in the development of new medical interventions, therapies, and healthcare strategies. Clinical Trials: Clinical trials are a specific form of clinical research designed to evaluate the safety and efficacy of medical interventions, including drugs, devices, treatments, and preventive measures. These trials are conducted in phases, each serving a distinct purpose in the research process.
Expansion of Clinical Research
Authors: Ordin Stanislav
Published: April 2024

The bureaucratically perverted Idea of expanding the Clinical Trials database can not only be corrected, but fundamentally advanced through information provided by patients themselves via the Internet. But in order to prevent the distortion of the Idea in the future, methods of processing Information are required based on the INVARIANT Medical Theory using the Mathematical Theory of Numbers and Sets, which will direct Artificial Intelligence to process an array of data about all sick people on Earth.
Pediatric Premature Aging Diseases
Authors: Bittmann Stefan
Published: April 2024

Pediatric premature aging disease are rarely found in pediatric population. The most known disease is Hutchinson Gilford Progeria (HGPS), but other very rare preaging diseases were described in detail. This brief report focuses on the most important preaging diseases in childhood, focus on pathogenesis and possible future therapeutical options.
Azithromycin and moxifloxacin resistance determinants in Mycoplasma genitalium in Lleida, Spain
Authors: Fraile García Lucía , Aramburu Arnuelos Jesús , López González Éric , Bellés-Bellés Alba , Muñoz Santa Alba , Sánchez Báscones Elena , Mormeneo Bayo Saray , Bernet Sánchez Albert , Prats Sánchez Iván , Cumplido Portillo, Alejandro , García González Mercè
Published: April 2024

Introduction. Mycoplasma genitalium (MG) is a microorganism related to sexually transmitted infections. Antibiotic resistance of MG leads to an increase in treatment failure rates and the persistence of the infection. The aim of this study was to describe the most frequent mutations associated with azithromycin and moxifloxacin resistance in our geographical area. Material and methods. A prospective study from May 2019 to May 2023 was performed. MG-positive samples were collected. Real-time PCRs (AllplexTM MG & AziR Assay and AllplexTM MG & MoxiR Assay, Seegene) were performed in MG positive samples to detect mutations in 23S rRNA V domain and parC gene. Results. A 37.1% of samples presented resistance determinants to azithromycin and the most common mutation detected was A2059G (57.9%). Resistance to moxifloxacin was studied in 72 azithromycin-resistant samples and 36.1% showed mutations, being G248T the most prevalent (73.1%). Conclusions. The resistance to different lines of treat ment suggests the need for a targeted therapy and the performing of a test of cure afterwards.
Empowering rheumatology through digital health technologies: contributions and barriers
Authors: Benavent Diego , Carmona Loreto , Llorente Jose Francisco García , Montoro María , Ramirez Susan , Otón Teresa , Loza Estíbaliz , Gómez-Centeno Antonio
Published: April 2024

Rheumatology, the medical specialty dealing with the diagnosis and treatment of rheumatic and musculoskeletal diseases (RMDs), is evolving with the emergence of digital health technologies, such as electronic health records (EHRs), virtual visits, mobile health (mHealth), wearable medical devices, social media, websites, digital therapeutics, artificial intelligence (AI) and machine learning. These technologies offer new opportunities to improve essential aspects of care, such as care access or disease management. They can significantly reduce the risk of errors and the workload of rheumatologists, while enhancing communication between physicians and patients, resulting in better quality of care. Moreover, digital health technologies can significantly improve research outcomes. However, digital health technologies in rheumatology also face specific barriers such as privacy, security concerns, incremental costs as well as limited digital health literacy and access. Therefore, further analysis, actions and strategies are needed to overcome these barriers. This article explores the impact of digital health technologies on rheumatology practice and highlights their contributions and challenges. By understanding the immense potential and overcoming the obstacles, the way for a future where digital health technologies are integrated into daily rheumatology care may be envisioned, in order to empower patients and healthcare providers.
Split Detour Monophonic Sets in Graph
Authors: Mahendran M. , Kavitha R.
Published: April 2024

A subset T ⊆ V is a detourmonophonic set of G if each node (vertex) x in G contained in an p-q detourmonophonic path where p, q ∈ T.. The number of points in a minimum detourmonophonic set of G is called as the detourmonophonic number of G, dm(G). A subset T ⊆ V of a connected graph G is said to be a split detourmonophonic set of G if the set T of vertices is either T = V or T is detoumonophonic set and V – T induces a subgraph in which is disconnected. The minimum split detourmonophonic set is split detourmonophonic set with minimum cardinality and it is called a split detourmonophonic number, denoted by dms(G). For certain standard graphs, defined new parameter was identified. Some of the realization results on defined new parameters were established.
Effect of Tensing Toe Relaxation Technique on Test Anxiety among B.Sc Nursing 1st Year Students in Selected Colleges, Bhubaneswar, Odisha
Authors: Soubhagya Ranjan Khilar  , Sivasankari Varadharasu  , Sanjukta Dixit  , Reena Singh
Published: April 2024

Background: Test anxiety is a psychological condition that causes extreme stress and anxiety in exam situations. Students feel stress and anxiety before exams. It can disrupt their learning and lead to poor performance. Relaxation techniques, like tensing toe relaxation, are the most effective non-pharmacological techniques for reducing stress because they affect mental and physical states like depression, mood, anxiety, and self-blaming.Objective: To evaluate the effect of the tensing toe relaxation technique on test anxiety among first-year B.S.nursing students and the association of the level of test anxiety with their selected demographic variables.Methods: The Quasi-experimental research study was conducted in two selected colleges in Bhubaneswar, Odisha, among B. Sc. Nursing 1st year students. Thirty-four (34) students were selected for each Experimental and Control group by using the Purposive sampling technique. Nist, Diehl A test anxiety scale and a self-structured socio-demographic tool were used for collecting the data through the questioning method. After demonstrating the tensing toe relaxation technique to the experimental group, they were asked to practice for 2 weeks. The post- test was conducted at the end of two weeks.Results: Study findings show a reduction of test anxiety with (t = 6.02) (p = 0.000), which is highly significant at p 0.001, and also the unpaired t-test post-test values show a significant change at p 0.001. Furthermore, there is a significant association between the level of test anxiety and selected demographic variables at p <0.05.Conclusion: The Tensing toe relaxation technique is an effective intervention to reduce test anxiety.
Educating Nurses about Safety measures in Handling Chemotherapy Drugs: A Pre-experimental Study
Authors: Asha Sajji  , Afrin Yusufi  , Annanya Chettri  , Bindhya Elsa James  , Josina Joy  , Pooja Hulimani  , Sharon Alex  , Sumit Saha
Published: April 2024

Background: Chemotherapy is used to treat cancer. Occupational exposure to chemotherapy drugs produce many side effects and continue to be a hazard in health care setting. It is therefore highly important for oncology nurses to apply proper drug handling technique and procedures with great care to prevent such exposure.Objectives: 1. To assess the level of existing knowledge of student nurses regarding safety measures in handling of chemotherapy drugs. 2. To determine the post-test level knowledge of student nurses regarding safety measures in handling of chemotherapy drugs. 3. To evaluate the effectiveness of structured teaching programme on knowledge regarding safety measures in handling of chemotherapy drugs. 4. To associate the post-test knowledge scores of the student nurses regarding safety measures in handling of chemotherapy drugs with their selected demographic variables.Design: Pre-experimental one group pre test post test design was selected for the study. Fifty 2nd year GNMstudents were selected through non-probability convenience sampling technique. A self-structured knowledge questionnaire was used to collect the data.Result: Findings of the study revealed that 36(72%) participants had inadequate knowledge & 13(26%) participants had moderately adequate knowledge in pre test. 28(56%) of the participants had adequate knowledge and 22(44%) had moderately adequate knowledge in post test. The obtained “t” value -12.22 was found to be highly significant at p<0.05 level.Conclusion: Teaching programmes are effective in improving the knowledge and hence must be conducted at regular intervals to retain the information.
Concrete as an eco-factor for climate change stabilization
Authors: Travush Vladimir I. , Kuzevanov Dmitry V. , Kaprielov Semyon S. , Volkov Yuri S.
Published: April 2024

The "Strategy for the development of the construction industry until 2030 and for the future until 2035" developed by the Ministry of Construction of Russia indicates that one of the goals of construction development for this future is to "reduce the carbon footprint from the impact of the construction industry on the environment. The article analyzes the factors that allow the main building material - concrete to make a significant contribution to reducing the carbon footprint in relation to the environment. Examples of European practices in solving this problem are given, the need for appropriate research work is indicated regarding the assessment of the impact of cement and concrete production on increasing the carbon footprint, the development of methods to solve this problem and taking this factor into account for practical needs.
The Relation Between Self-Esteem and Body Dissatisfaction
Authors: Hysi Fatjona
Published: April 2024

The main goal of this article is to explore the connection that exists between body dissatisfaction and ranges of self-esteem in undergraduate students in the Department of Psychology of University of Tirana. The method applied for the deployment of the present study is a Quantitative with a Cross-sectional Descriptive-Correlational layout and a non-probabilistic sort of comfort or intentional sampling. The sample of the present research is composed of 120 undergraduate students. The instruments that have been used within this study include; the Body Shape Questionnaire (BSQ) and the Coopersmith Self-Esteem Inventory. Data were examined through SPSS version 27. Results showed an inversely proportional correlation. Indices show that the higher the level of self-esteem, the lower the degrees of body dissatisfaction. In conclusion, it was observed that students reveal a greater influence of the external and social factors in their overall body dissatisfaction.
Cross-language Exploration: a way to explore the use of L1 in the classroom at a Southeastern Mexican University
Authors: Arias de la Cruz Andrés , Morales Vázquez Eleazar , Arias Ovando Julio César , Silván Almeida Rolando Guadalupe
Published: April 2024

The place of the First Language (L1), in the classroom has been studied by many researchers in relation to the advantages and disadvantages of the use of the mother tongue in foreign language (FL) courses. This study aimed at uncovering the main reasons for which participants use the L1, in this case Spanish in an EFL course and finding out students’ perceptions of the use of their L1 in an EFL course. This study was carried out at a Mexican undergraduate programme. Participants were 11 students who were enrolled in a basic English course from a business and economics undergraduate programmes during the first semester of 2019. The study used a qualitative method and followed an action research design. Data were collected through observation in situ, a questionnaire and a cross-language exploration assessment task. Findings reveal that the participants have a great acceptance of the Spanish use in the English class. Most of the participants agreed that they use Spanish for different reasons: to translate vocabulary, to socialize, to ask questions, to participate, to compare answers or vocabulary, and to compare similarities and differences between L1 and EFL.  All in all, the use of the Spanish is something that is always present in language courses. Despite the generalized idea of it causing detrimental effects on the target language learning; this study showed that it can render positive effects, at least at early stages of the EFL learning process.
European Union politicians debating European language education policy
Authors: Lanvers Ursula
Published: April 2024

The European Union’s (EU) high regard for multilingualism and linguistic diversity is expressed through its language education policy (LEP), a policy adopted by the European Parliament, which represents all EU member states. However, as education falls within the remit of the member states, EU LEP has an advisory function only. Support for the LEP at national level is thus crucial. By analysing a significant parliamentary discussion by Members of the European Parliament (MEPs), this article asks what evidence there is that MEPs support the EU’s goals of learning the mother tongue plus two foreign languages (1+2), and of learning a diversity of languages at school. Secondly, the article investigates current evidence of the success of EU LEP in terms of developing dual language capacities, and of maintaining diversity in language learning. Figures on the learning of two languages, on the learning of English, and on linguistic diversity are compared, covering the last decade. The results reveal that although the training of dual linguists has stagnated, no MEP expressed concerns that the EU goals of 1+2 are not being met. MEPs are, however, concerned with protecting ‘their’ national languages, and the smaller ‘their’ own language(s), the more so. Furthermore, only representatives of large EU languages express concern over English dominance in the EU’s education systems. Thus, parliamentary representatives of smaller languages unite in solidarity for greater status recognition of their language, while MEPs’ support for the EU LEP goal of 1+2 is at best patchy. The article concludes that, given the limited remit of EU LEP, discrepancies between European recommendations and national practices are somewhat inevitable, and that to improve on the 1+2 goal and counter English dominance across education systems in the EU, member states need to be better supported to appreciate and disseminate the rationales for dual language learning (1+2) and diversity in language learning.
The Weakness of Soft X-Ray Intensity: Possible Physical Reason for Weak-line Quasars
Authors: Wu Jiancheng , Wu Qingwen , Jin Chichuan , Wu Jianfeng , Lei Weihua , Cao Xinwu , Fan Xiao , Lei Xiangli , Wang Mengye , Xue Hanrui , Lyu Bing
Published: April 2024

Weak-line quasars (WLQs) are a notable group of active galactic nuclei (AGNs) that show unusually weak UV lines even though their optical-UV continuum shapes are similar to those of typical quasars. The physical mechanism for WLQs is an unsolved puzzle in the AGN unified model. We explore the properties of UV emission lines by performing extensive photoionization calculations based on Cloudy simulations with different spectral energy distributions (SEDs) of AGNs. The AGN continua are built from several observational empirical correlations, where the blackbody emission from the cold disk, the power-law emission from the hot corona, and a soft X-ray excess component are considered. We find that the equivalent width (EW) of C iv from our models is systematically lower than observational values if the component of soft X-ray excess is neglected. The EW will increase several times and is roughly consistent with the observations after considering the soft X-ray excess component as constrained from normal type I AGNs. We find that the UV lines are weak for QSOs with quite large black hole mass (e.g., M
BH > 109
M
⊙) and weak soft X-ray emission due to the deficit of ionizing photons. As an example, we present the strength of C iv based on the multiband SEDs for three nearby weak-line AGNs, where the weaker soft X-ray emission normally predicts the weaker lines.
Multiple Patchy Cloud Layers in the Planetary-mass Object SIMP 0136+0933
Authors: McCarthy Allison M. , Muirhead Philip S. , Tamburo Patrick , Vos Johanna M. , Morley Caroline V. , Faherty Jacqueline , Bardalez Gagliuffi Daniella C. , Agol Eric , Theissen Christopher
Published: April 2024

Multiwavelength photometry of brown dwarfs and planetary-mass objects provides insight into their atmospheres and cloud layers. We present near-simultaneous J- and K

s
-band multiwavelength observations of the highly variable T2.5 planetary-mass object, SIMP J013656.5+093347. We reanalyze observations acquired over a single night in 2015 using a recently developed data reduction pipeline. For the first time, we detect a phase shift between J- and K

s
-band light curves, which we measure to be

39

.°

9

−
1.1

+
3.6

. Previously, phase shifts between near-infrared and mid-infrared observations of this object were detected and attributed to probing different depths of the atmosphere, and thus different cloud layers. Using the Sonora Bobcat models, we expand on this idea to show that at least two different patchy cloud layers must be present to explain the measured phase shift. Our results are generally consistent with recent atmospheric retrievals of this object and other similar L/T transition objects.
The Impact of Ambipolar Diffusion on the Rossby Wave Instability in a Protoplanetary Disk
Authors: Gholipour Mahmoud
Published: April 2024

Recent observational and simulation studies have revealed that ambipolar diffusion is an important phenomenon in the outer regions of a protoplanetary disk (PPD). However, numerous simulation studies have found that ambipolar diffusion suppresses the turbulence caused by the magnetorotational instability (MRI) in these regions of a PPD. The aim of this study is to investigate the impact of ambipolar diffusion on the Rossby wave instability (RWI) at large radii of a PPD. To accomplish this, we examine the occurrence of the RWI in a PPD threaded by the magnetic field in the presence of ambipolar diffusion. Additionally, we scale the ambipolar diffusivity with respect to both the toroidal magnetic field and an important parameter known as the Elsässer number. We obtain the growth rate of unstable RWI modes in the outer regions of a PPD using linear perturbation analysis. In our nonaxisymmetric perturbation analysis, we find that the amplitude of the toroidal field oscillates in various modes for small values of the Elsässer numbers. For small Elsässer numbers, the growth rate of unstable modes associated with the RWI decreases. In other words, ambipolar diffusion suppresses the perturbation caused by the RWI. This effect is similar to the effect of ambipolar diffusion on the MRI. In contrast to the MRI, where there is a range around 1 for the Elsässer numbers, the existence of ambipolar diffusion supports the occurrence of RWI. Finally, we compare our findings with those of simulation studies to emphasize the importance of RWI in the outer regions of a PPD.
Bischofia javanica and Phaleria macrocarpa nano herbal combination on blood and liver-kidney biochemistry in Oral Squamous Cell Carcinoma-induced rats
Authors: Rumahorbo Cheryl Grace Pratiwi , Ilyas Syafruddin , Hutahaean Salomo , Fatimah Zuhra Cut
Published: April 2024

This research explores a contemporary approach to managing Oral Squamous Cell Carcinoma (OSCC) by integrating nano-technology into herbal production, combining Bischofia javanica leaves and Phaleria macrocarpa fruits. Benzo[a]pyrene (BaP)-induced OSCC rats were treated with nano herbals from Bischofia javanica leaves, Phaleria macrocarpa fruits, a combination of both, and Vitamin C as a control. Blood and organ analyses were compared with negative and positive controls. BaP induction in OSCC revealed cell transformation into carcinoma, confirmed by Papanicolaou staining. OSCC induction also caused significant changes in Complete Blood Count (CBC) and serum lipid profile. Nano herbals from both plants showed potential in reducing hematological and lipid damage in OSCC, especially in white blood cells, red blood cells, hemoglobin, and platelets. Statistical analysis also indicated that the combination of nano herbals was more effective in reducing (Low-Density Lipoprotein) LDL and total cholesterol levels than uncombined use while increasing (High-Density Lipoprotein) HDL levels comparable to Vitamin C. Liver and kidney functions were also significantly affected by OSCC, with nano herbals showing potential in normalizing albumin levels and positively impacting liver enzymes. In conclusion, both individually and in combination, nano herbals from Bischofia javanica leaves, and Phaleria macrocarpa fruits have the potential to be a promising treatment strategy for OSCC.
Signal transduction in wound healing: The effects of plant-derived biologically active substances
Authors: Esad Merlin , Popova Mihaela , Apostolova Elisaveta , Bivolarska Anelia
Published: April 2024

Wounds are among the most common skin diseases. They are formed after tissue injury and result in severe damage to the epidermis. The application of plants for wound healing is not only a cheap and accessible way of treatment, but also provides a reliable natural resource of medicinal substances with fewer side effects. Biologically active substances such as alkaloids, essential oils, flavonoids, tannins and phenolic compounds demonstrate a wide spectrum of action: wound healing, anti-inflammatory, antibacterial and antioxidant effects.

This review article examines the chemical composition of three plants - Calendula officinalis, Marrubium vulgare, Vitis vinifera and the signal transduction in skin wound healing. Studies have shown that they have a strong antioxidant effect, hemostatic activity, powerful vasoconstrictor effect, pro-angiogenic and cell-protective effects.

Because of the mentioned benefits of these plants, more scientific research and well-designed clinical trials are needed to establish their wider use in wound treating medicaments.
Thliphthisa sapphus (Rubiaceae, Rubieae), a new species from Lefkada (Ionian Islands, Greece) and its ecological position
Authors: Gutermann Walter , Jang Tae-Soo , Kästner Arndt , Prehsler David , Reich Dieter , Berger Andreas , Flatscher Ruth , Gilli Christian , Hofbauer Markus , Lachmayer Margarita , Sander Ruth , Sonnleitner Michaela , Mucina Ladislav
Published: April 2024

The new species, Thliphthisa sapphussp. nov. (Rubiaceae, Rubieae), a narrow endemic of the white cliffs of Lefkátas on the southwest coast of Lefkada (Greece) is described and illustrated and an IUCN assessment is presented. Vegetation relevés were performed at the single known locality, limestone cliffs facing the sea and revealed a new association, the Thliphthisa sapphus-Lomelosietum dallaportae. The chromosome number of Thliphthisa sapphus was determined as 2n = 4x = 44, being the single tetraploid species in the genus to date. The species also differs markedly morphologically from its morphologically closest relatives, two Greek steno-endemic oreophytes, Th. baenitzii and Th. muscosa by the following characters: densely setose mericarps and corolla, tetraploidy and by its distribution. An identification key for the Greek species of Thliphthisa is provided. Th. sapphus constitutes the westernmost outpost of a group of Greek steno-endemics, highlighting the importance of coastal habitats and their protection as refugia for poorly competitive chamaephytes.