bluuebunny/crossref_metadata_2025 huggingface dataset:
A produção de portfólios digitais como técnica para a compreensão da história humana
Authors: Pommer Roselene Moreira Gomes , Martins Sebastian
Published: August 2022

Diante dos desafios que as chamadas Novas Tecnologias da Informação e da Comunicação (NTIC) têm apresentado à educação em geral, qual tem sido o papel dos conhecimentos históricos para a formação de jovens trabalhadores? A reflexão sobre essa questão é apresentada no presente texto através da análise de uma ação pedagógica desenvolvida com estudantes de cursos técnicos integrados do Colégio Técnico Industrial de Santa Maria (CTISM). A ação referida resultou na produção de portfólios digitais contendo abordagens sobre as realizações técnicas produzidas pelos grupos sociais durante o período histórico comumente identificado como modernidade. O método utilizado para refletir-se sobre a atividade foi o analítico descritivo que poderá apontar as razões para a compreensão do problema inicialmente apresentado e, a partir disso, indicar as possibilidades de sua superação. A abordagem teórica escolhida para a reflexão foi aquela apresentada por Pinto (2005) para quem o homem, sendo um animal técnico, produz-se na medida de suas ações que são técnicas.
Legado de Ana Célia da Silva: trajetória de ações afirmativas da militância à produção acadêmica
Authors: Franco Nanci Helena Reboucas
Published: August 2022

A presente entrevista tem como objetivo analisar as contribuições  acadêmicas e profissionais da Profa Dra. Ana Célia da Silva, uma intelectual insurgente no campo da educação, que atrela militância e produção acadêmica, na luta contra o racismo na educação brasileira. Fundadora do Movimento Negro Organizado (MNU) e do primeiro Grupo de Trabalho sobre Educação – o grupo de Trabalho Robson da Luz – uma das reivindicações do movimento. Professora Titular aposentada da Universidade do Estado da Bahia (UNEB), atuou na graduação e no Programa de Pós-Graduação em Educação e Contemporaneidade do  Departamento de Educação/Campus 1, centrando as suas contribuições teóricas sobretudo nos seguintes temas: negro  e educação, educação das relações étnico-raciais, currículo, estereótipos, desconstrução, e representação social do negro nos livro didático de Língua Portuguesa das séries iniciais. Autora de uma lista extensa de artigos publicados em periódicos nacionais, de capítulos de livros e outras produções técnicas que são referência nas temáticas supracitadas. Entre os livros publicados estão “A Discriminação do Negro no Livro Didático” (EDUFBA, 1995), “Desconstruindo a Discriminação do Negro no Livro Didático” (EDUFBA, 2001), A Representação Social do Negro no Livro Didático: O que mudou? Por que mudou?” (EDUFBA, 2011) “Retrospectiva de uma trajetória de ações afirmativas precursoras à Lei 10.639/03” (HETERA, 2017). Em reconhecimento a sua trajetória de  pesquisadora militante, precursora na luta pelo combate ao racismo, especialmente na educação e a favor da cultura afro-brasileira, recebeu inúmeros prêmios, com destaque para Troféu Zilda Paim  concedido pela Assembleia Legislativa da Bahia e a Medalha Zumbi dos Palmares, pela Câmara Municipal de Salvador.
The Relationship Between the Exchange Rate, Trade Terms and Employment in Turkey
Authors: Salah Uddin Muhammad , Ahmed Zobayer , Hasan Mahadi
Published: August 2022

The objective of this paper is to analyze the impact of real exchange rate (RER) on employment and real wage using quarterly disaggregated data (ISIC Rev 4 classification) composed of 19 industries in Turkey from 2010 to 2017. This study employed the Fixed Effect Model, where industry-specific effects are used to control heterogeneity within the industry. The results reflect that currency appreciation negatively affects employment, though insignificant, whereas it has a remarkably positive impact on real wage. Although the terms of trade have no visible impact on employment and real wages, the study uniquely finds that the effects of the larger industries on employment are distinctly adverse. Nevertheless, the interaction between currency appreciation and the top 25 per cent larger industries indicates a moderate increase in employment. The findings reflect that the appreciation of the domestic currency causes employment to decrease at the industry level. The originality of this paper includes the effects of the terms of trade and interaction with currency appreciation in larger industries using the Fixed Effect Model approach.
Zabójstwa seryjne w Polsce oraz ich sprawcy w ujęciu kryminologicznym
Authors: Góralski Piotr
Published: August 2022

Artykuł przedstawia sylwetki i kariery przestępcze sprawców zabójstw seryjnych popełnionych Polsce w latach 1922–2021, wraz z analizą przyczyn dokonywania tego typu przestępstw. Celem tej publikacji jest między innymi weryfikacja prawdziwości tezy, że na terenie Polski zabójstwa seryjne popełniane są w bardzo niewielkiej ilości. Aby to zrobić, odwołano się do opracowań o charakterze kryminologicznym oraz do orzecznictwa sądowego. Z omówień zawartych w prezentowanym artykule wynika, że zabójstwo seryjne nie jest bynajmniej zjawiskiem rzadkim w praktyce polskiego wymiaru sprawiedliwości. Częstotliwość jego występowania utrzymuje się na stałym poziomie, niezależnie od zbiorczej liczby zabójstw oraz zmian społeczno-gospodarczych i ustrojowych — choć niektóre specyficzne formy i przejawy tego typu zachowań występowały w różnych częstotliwościach w okresach międzywojennym, komunizmu oraz po roku 1989 (na przykład seryjne dzieciobójstwa czy zabójstwa wielokrotne popełniane w ramach przestępczości zorganizowanej). W pierwszej części artykułu dokonano rozróżnienia i scharakteryzowania pojęć „zabójstwo seryjne” oraz „seryjny zabójca”, jak również wskazano relacje treściowe zachodzące między tymi terminami. W tekście wyodrębniono też pojęcie potencjalnego sprawcy zabójstw seryjnych oraz wyszczególniono przykłady przestępstw popełnionych przez takie osoby. Następnie odwołano się do najbardziej znanych przypadków sprawców wielokrotnych zabójstw na terenie Polski, aby na tych przykładach przedstawić przyczyny, a w szczególności podłoże motywacyjne dokonywania tego typu zbrodni oraz prawne możliwości ich zwalczania.
“A vida é bela”: para ler legendas e para humanizar-se
Authors: Arena Dagoberto Buim , Kohle Érika Christina , Santos Sônia de Oliveira
Published: August 2022

A aprendizagem de atos de ler em ambientes escolares pode resultar do encontro de crianças com a pluralidade de gêneros dos enunciados, com suportes vários e mídias. Filmes legendados oferecem às crianças as condições para que aprendam a negociar, no silêncio, os sentidos das legendas. Este artigo relata uma atividade de pesquisa e de extensão com o filme italiano “La vita è bella” (“A vida é bela”), desenvolvida com um pequeno grupo de crianças, entre 6 e 10 anos, em uma organização não governamental (ONG), em Marília, SP, apoiada nos princípios de metodologia das ciências humanas desenvolvidos por Bakhtin e no conceito de massa aperceptiva de Jakubinskij. Os diálogos entre crianças e pesquisadores, gravados e analisados sob a lente desse referencial, evidenciam que as crianças aprendem a negociar rapidamente sentidos; interessam-se por debater temas tensos, como a opressão e a violência contra crianças e minorias étnicas e, por essa razão, humanizam-se; tornam-se também, pouco a pouco, apreciadoras de filmes com boa qualidade estética.
Percepções dos egressos sobre a formação no curso de Fisioterapia da Universidade de Sorocaba
Authors: Rossi Mateus Francisco , Pinto Rafael Ângelo Bunhi
Published: August 2022

O estudo tem por objetivo detalhar o perfil dos egressos do curso de Fisioterapia da Universidade de Sorocaba (UNISO) e analisar as percepções desses egressos sobre sua formação superior relacionada à atuação profissional, de forma que possam contribuir para o aprimoramento do curso. Quanto à metodologia, realizou-se um estudo de caso, de caráter qualitativo e quantitativo, com questionário autoaplicável, em uma amostragem não probabilística intencional, abordando aspectos como: identificação, percurso na graduação, inserção no mercado de trabalho, mobilidade educacional, avaliação do processo de formação em Fisioterapia e satisfação com o curso e a profissão. Nos resultados e na discussão, pode-se constatar que os egressos do curso de Fisioterapia da UNISO são, em sua maioria, mulheres, de cor branca, abaixo de 28 anos, que frequentaram ensino médio em escola pública, cujo pais não cursaram ensino superior, realizam pós-graduação, consideram-se satisfeitos com a profissão e com o curso de Fisioterapia, especialmente com os conteúdos práticos, específicos e relacionados a uma formação humanista e integral. Entraram rapidamente no mercado de trabalho e obtiveram ascensão social trabalhando como fisioterapeutas, mas apontam insatisfação referente à remuneração e sugerem direcionamento do curso em aspectos relacionados ao empreendedorismo e preparo para o mercado de trabalho.
Profil kemampuan berpikir kritis dan kreatif siswa SMA terhadap revolusi industri 4.0 dan masyarakat 5.0
Authors: Rahmadani Yesika , Puti Tunjung Nala
Published: August 2022

Pada era Pendidikan 4.0, siswa bertanggung jawab untuk menentukan jalur pendidikan mereka sendiri yang juga mengarah pada konsep pembelajaran yang dipersonalisasi. Education 4.0 juga memperkenalkan learning analytics (LA). Society 5.0 sebagai ide perintis diharapkan mampu menyelesaikan persoalan ini, perlu banyak pengembangan terutama dalam hal teknologi untuk “mengangkat” masyarakat era kelima ini. Untuk melakukan revolusi besar-besaran, diperlukan modal yang cukup kuat. Tujuan penelitian ini adalah untuk mengetahui profil kemampuan berpikir kritis dan kreatif siswa terhadap revolusi industri 4.0 dan masyarakat 5.0. Subjek penelitian ini adalah siswa SMA dengan jumlah 47 siswa. Subjek dipilih dengan teknik random sampling di salah satu SMA di Solo Raya. Responden diwajibkan untuk mengisi kuisioner yang diberikan. Data diperoleh dengan menggunakan kuesioner yang terdiri dari 33 pertanyaan. Berdasarkan pengolahan data yang telah dilakukan menunjukkan bahwa kemampuan berpikir kritis dan berpikir kreatif siswa masih perlu ditingkatkan. Kemampuan berpikir kritis siswa berada pada kategori sedang, sedangkan kemampuan berpikir kreatif siswa berada pada kategori rendah.

 

Profile of high school students' critical and creative thinking ability to industrial revolution 4.0 and society 5.0. Education 4.0, students are responsible for determining their own educational path which also leads to the concept of personalized learning. Education 4.0 also introduced learning analytics (LA). Society 5.0 as a pioneering idea hoped to be able to resolve this issue, it needs a lot of developments, especially in terms of technology to "pick up" this fifth era of society. In order to carry out a large-scale revolution, it is necessary to have sufficiently strong capital. The purpose of this study was to determine the profile of students' critical and creative thinking skills towards the industrial revolution 4.0 and society 5.0. The subjects of this study were high school students with a total of 47 students. Subjects were selected using a random sampling technique in a high school in Solo Raya. Respondents are required to fill out a questionnaire given. The data obtained by using a questionnaire consisting of 33 questions. Based on the data processing that has been done, it shows that students' critical thinking and creative thinking skills still need to be improved. Students 'critical thinking skills are in the medium category, while students' creative thinking skills are in the low category.
Penerjemahan Komunikatif Cerita Anak Nasâihu Muhmalah Karya Zakaria Tamer
Authors: Ghaidaq Haulidam Hamdan , Abshar Ulil , Suparno Darsita
Published: August 2022

This study aims to describe the results of the communicative translation method in the children's story book Nasâihu Muhmalah by Zakaria Tamer. The research method used in this research is qualitative-descriptive with a descriptive translation approach. primary data sourced from the original children's story book Nasâihu Muhmalah written by Zakaria Tamer and supported from secondary data in the form of books, journals and other references that are accessed on the internet, relying on books related to translation, literary books specifically related to children's literature. The research data collection technique was carried out through several stages, namely selecting the corpus, ensuring that the corpus had never been studied, understanding the contents of the corpus, translating the entire contents of the book and evaluating the accuracy of the translation results. The results showed 10 translation data using the following translation strategies: taqdim and ta'khir (putting forward and ending), ziyadah (adding), hadzf (removing) and tabdil (replacing). While the translation techniques used are technique, adaptation, reduction and literal.

Abstrak

Penelitian ini bertujuan untuk mendeskripsikan hasil metode penerjemahan komunikatif pada buku cerita anak Nasâihu Muhmalah karya Zakaria Tamer. Metode penelitian yang digunakan dalam penelitian ini adalah kualitatif-deskriptif dengan pendekatan terjemahan deskriptif. data primer bersumber dari buku cerita anak aslinya Nasâihu Muhmalah karangan Zakaria Tamer dan didukung dari data sekunder berupa buku-buku, jurnal dan refrensi lainnya yang diakses di internet, mensandarkan kepada buku yang berhubungan dengan penerjemahan, buku-buku sastra yang khususnya berhubungan dengan sastra anak. Teknik pengumpulan data penelitian dilakukan melalui beberapa tahap, yakni memilih korpus, memastikan bahwa korpus belum pernah diteliti, memahami isi korpus, menerjemahkan keseluruhan isi buku dan mengevaluasi ketepatan hasil terjemahan. Hasil penelitian menunjukkan 10 data penerjemahan dengan menggunakan strategi penerjemahan berikut: taqdim dan ta’khir (mengedepankan dan mengakhirkan), ziyadah (menambahkan), hadzf (membuang) dan tabdil (mengganti). Sementara teknik penerjemahan yang digunakan adalah teknik, adaptasi, reduksi dan harfiah.
Incidence of hypoxemia with high-flow nasal oxygenation versus facemask oxygenation in patients at risk of hypoxemia undergoing bronchoscopy: A randomised controlled trial
Authors: Zhang Wen , Wang Jiang-Ling , Fu Shuang , Zhou Jia-Ming , Zhu Ye-Jing , Cai Shu-Nv , Fang Jun , Chen Xin-Zhong , Xie Kang-Jie
Published: August 2022

Background: Patients at high risk of obstructive sleep apnea (OSA) are prone to hypoxemia during sedated bronchoscopy. The present study aimed to investigate whether high-flow nasal oxygenation (HFNO) reduces the incidence of hypoxemia in patients at high risk of OSA undergoing bronchoscopy under deep sedation.Methods: A total of 176 patients at high risk of OSA who underwent bronchoscopy under deep sedation were randomly assigned into two groups: the HFNO group (humidified oxygen was supplied via a high-flow nasal cannula at a rate of 60 L/min and a concentration of 100%, n = 87) and the Facemask group (oxygen was supplied via tight-fitting facemask at a rate of 6 L/min and a concentration of 100%, n = 89).Results: Hypoxemia occurred in 4 (4.6%) patients in the HFNO group and 26 (29.2%) patients in the Facemask group (P < 0.001). The Facemask group required more jaw thrust maneuvers than the HFNO group (48.3% vs 5.7%, P < 0.001). A total of 9.0% of the patients in the Facemask group and no one in the HFNO group required bag-mask ventilation (P = 0.012).Conclusions: HFNO can reduce the incidence of hypoxemia and the requirement of airway intervention in patients at high risk of OSA during bronchoscopy under deep sedation.Trial registration: www.chiCTR.org.cn Identifier: ChiCTR2100044105. Registered 11/03/2021.
Evaluation of the coagulation properties of magnesium hydroxide for removal combined contamination of reactive dyes and microfibers
Authors: Duan Yingying , Zhao Jianhai , Qiu Xiuming , Deng Xiaoli , Ren Xiaoyu , Ge Wenqi , Yuan Hongying
Published: August 2022

Microfibers are a new type of pollutants that are widely distributed in water bodies. And the simultaneous removal of pollutants in water is popular research in the field of water treatment. In this study, magnesium hydroxide was used as coagulant to investigate the performance and mechanism of coagulation and removal of dyes (reactive orange) and microfibers (MFs). The presence of dyestuff in the composite system promoted the removal of microfibers, and the maximum removal efficiency of both could reach 95.55% and 95.35%. The coagulation mechanism was explored by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and zeta potential. The removal of reactive orange and microfibers relied on electrical neutralization, sweep flocculation and adsorption mechanisms. Turbidity can enhance the removal efficiency of both. Boosting the rotational speed can increase the removal efficiency of microfibers. This study provides an important theoretical support for an in-depth understanding of the characteristics and mechanisms of coagulation for the removal of complex pollutants from printing and dyeing wastewater.
Effect of different low doses of intrathecal morphine (0.1 and 0.2 mg) on pain and vital functions in patients undergoing total hip arthroplasty: a randomised controlled study
Authors: Buraka Natalija , Erts Renars , Golubovska Iveta , Miscuks Aleksejs , Vitola Eva
Published: August 2022

BackgroundOrthopaedic surgeries are among the most painful procedures. Pоstоperаtive pаin аdversely аffeсts the reсоvery оf pаtients. By adding low-dose morphine to intrathecal bupivacaine for spinal anasthesia, the analgesic effect can be prolonged and improved. The objeсtive of the study was tо compare the efficacy and safety of lоw-dоse (0.1 mg аnd 0.2 mg) intrаtheсаl mоrphine (ITM).MethodsА prоspeсtive rаndоmised study was соnduсted аt the Hоspitаl оf Trаumаtоlоgy аnd Оrthоpaediсs, Riga, Latvia, frоm February 2020 tо May 2021. The study enrolled 90 subjects whо met the inclusion criteria and were scheduled for total hip аrthrоplаsty. All subjects were randomised intо three study grоups, using the online tool оn www.randomiser.org. All groups received spinal anaesthesia with bupivacaine 15 to 18 mg. Grоup I was the control group. Grоup II and Group III received, respectively, 0.1 mg and 0.2 mg of morphine intrathecally. All subjects received the same multimodal аnаlgesiа. Pаin levels were assessed at rest in 4 h, 7 h, 12 h аnd 24 h post-surgery. Respiratory rate, SpО2, morphine соnsumptiоn, оxygen supply and аdverse reасtiоns (nаuseа, vоmiting, pruritus, etс.) were monitored for 24 h. Dаtа were аnаlysed using R version 4.2.0 (R Core Team, 2022) and applying the Mann-Whitney test, Pearson’s chi-squared test, Fisher’s exact test, Friedman test and Wilcoxon test.ResultsPаin sсоre in Groups I, II аnd III, respectively: 4 h – 1.21, 0.48, 0.17 (p = 0.068); 7 h – 2.62, 1.00, 0.17 (p < 0.001); 12 h – 3.08, 0.65, 0.37 (p < 0.001); 24 h – 2.50, 1.20, 0.41 (p = 0.001). Rescue medication requests (incidence, %): Grоup I – 77%, Group II – 16.7%, Group III – 13.3% (p < 0.001). Respiratory rate (x/min) (min; mаx): Group I – 16.1 (13.0, 20.0); Grоup II – 15.2 (10.5, 19.0); Grоup III – 15.2 (11.5, 20.0) (p > 0.05). SpO2 (%): Group I – 96.7% (92.0%, 100.0%); Grоup II – 95.7% (92.0%, 99.5%); Grоup III – 96.07% (91.0, 100). Significant adverse effects: pruritus in Grоup III (23% оf subjects, p < 0.001).ConclusionThe study results confirm that 0.2 mg of ITM holds the best analgesic effect for THA patients.Study registration: study ID ISRCTN37212222; 20/04/2022 (registered retrospectively)
Tribological and Mechanical Characteristics of Mg-Zn6.0-Y1.2-Zr0.2 alloy by SPS Technique: Natural and Agro Waste Utilization
Authors: Vinod B , Suresh S , Reddy S Sunil Kumar , Sujith S Sai
Published: August 2022

In India, urban solid waste generation has risen over the last decade. The aspect of waste generation is a large amount of waste materials among all solid waste types. While using ash particles eliminates waste, it also contributes desirable qualities. In this research work, the effects of Himalayan nettle leaf ash (HNLA) bean pod ash (BPA) with molybdenum trioxide (MoO3) on the ZWK611 (Mg-Zn6.0-Y1.2-Zr0.2) alloy is examined. The as-cast alloy exhibits an α-Mg matrix, and cubic γ-phases are formed in addition to MoO3 particles. In this work, an attempt was made to choose a ZWK611 alloy reinforced with HNLA and BPA by varying weight percentages (X = 4, 8, 12, and 15%) with a constant weight percentage of MoO3 (5%) fabricated using spark plasma sintering (SPS) technique. The mechanical and physical properties were tested for both as-cast alloy and magnesium hybrid composites. Surface morphology and XRD are analysed to identify material behaviour. The addition of 12%(HNLA-BPA)/5%(MoO3) hybrid composite exhibits high strength as compared to the as-cast alloy.
Development and Validation of a Novel Scoring System to Quantify the Severity of Incident Reports Using Machine Learning: An exploratory research study
Authors: Uematsu Haruhiro , Uemura Masakazu , Kurihara Masaru , Umemura Tomomi , Hiramatsu Mariko , Kitano Fumimasa , Fukami Tatsuya , Nagao Yoshimasa
Published: August 2022

Incident reporting systems have been widely adopted to collect information about patient safety incidents. The value of incident reports often lies in the free-text section, but this is often inadequately processed. We developed a novel scoring system that uses machine learning to assess the severity of an incident using the semantic characteristics of text in incident reports. We retrospectively analyzed free-text data extracted from incident reports from between January 2012 and September 2021 at Nagoya University Hospital, Aichi, Japan. The sample was randomly allocated into a training dataset and validation dataset. Morphological analysis was used to segment terms using the training dataset. We calculated a severity term score, a severity report score and severity group score, by the report volume size. We then compared these with conventional severity classifications by patient safety experts and reporters. We allocated 96,082 incident reports into two groups. From the 48,041 reports in the training dataset, 1,802 severity term scores were calculated. There was a significant difference in severity report score between reports categorized as severe and not severe by experts (95% confidence interval [CI] − 0.83 to − 0.80, p < 0.001). Severity group scores were positively associated with severity ratings from experts and reporters, with correlation coefficients of 0.73 (95% CI 0.63–0.80, p < 0.001) and 0.79 (95% CI 0.71–0.85, p < 0.001) for all departments. Our severity scoring system using machine learning could contribute to improved organizational patient safety.
Expansion of KRAS hot spot mutations reactive T cells from human pancreatic tumors using autologous T-cells as the antigen-presenting cells
Authors: Wang Sizhen , Zhang Xiaohui , Zou Xuemei , Wen Maorong , Gan Chi , Jiang Xiaochun , Yu Guangjie , Hu Hong-Ming , Yu Fang , Long Yaoan , Jun Zhudao , Xi Shenrong , Li Min , Wang Xinbo
Published: August 2022

Adoptive cell therapy (ACT) with expanded Tumor-infiltrating lymphocytes (TIL) or TCR gene-modified T cells (TCR-T) that recognize mutant KRAS neo-antigens can mediate tumor regression in patients with advanced pancreatic ductal adenocarcinoma (PDAC) (1 2). The mutant KRAS targeted ACT holds great potential to achieve durable clinical responses for PDAC, which has had no meaningful improvement over 40 years. However, the wide application of mutant KRAS-centric ACT is currently limited by the rarity of TIL that recognize the mutant KRAS. In addition, PDAC is generally recognized as a poorly immunogenic tumor, and TILs in PDAC are less abundant than in immunogenic tumors such as melanoma. To increase the success rate of TIL production, we adopted a well-utilized K562-based artificial APC (aAPC) that expresses 4-1BBL as the costimulatory molecules to enhance the TIL production from PDCA. However, stimulation with K562-based aAPC led to a rapid loss of specificity to mutant KRAS. To selectively expand neo-antigen-specific T cells, particularly mKRAS, from the TILs, we used tandem mini gene-modified autologous T cells (TMG-T) as the novel aAPC. Using this modified IVS protocol, we successfully generated TIL cultures specifically reactive to mKRAS(G12V). We believe that autologous TMG-T cells provide a reliable source of autologous APC to expand a rare population of neoantigen-specific T cells in TILs.
Influence of Magnetic Nanoparticle Biotransformation on Contrasting Efficiency and Iron Metabolism
Authors: Yaremenko Alexey V. , Zelepukin Ivan V. , Ivanov Ilya N. , Melikov Roman O. , Pechnikova Nadezhda A. , Dzhalilova Dzhuliia Sh. , Mirkasymov Aziz B. , Bragina Vera A. , Nikitin Maxim P. , Deyev Sergey M. , Nikitin Petr I.
Published: August 2022

Magnetic nanoparticles are widely used in biomedicine for MRI imaging and anemia treatment. The aging of these nanomaterials in vivo may lead to gradual diminishing of their contrast properties and inducing toxicity. Here we describe observation of the full lifecycle of 50-nm magnetic particles from their injection to the complete degradation in vivo and associated impact on the organism. We found that in 2 hours nanoparticles were eliminated from the bloodstream, but their initial biodistribution changed over time. In 1 week major part of nanoparticles was transferred to the liver and spleen, where they degraded with a half-life of 21 days. MRI and magnetic spectral approach revealed preservation of contrast in these organs for more than 1 month. Particle degradation led to increased number of red blood cells and blood hemoglobin level due to released iron without causing any toxicity in tissues. Also, we observed an increase in gene expression level of Fe-associated proteins such as transferrin, DMT1 and ferroportin in the liver in response to iron particle degradation. A deeper understanding of the organism response to the particle degradation can bring new directions to the field of MRI contrast agent design.
NLRP3 plays a key role in antihelminth immunity in the enteral and parenteral stages of Trichinella spiralis-infected mice
Authors: Pan Tian-Xu , Huang Hai-Bin , Zhao Guang-Xun , Quan Yu , Li Jun-Yi , Xue Ying , Lu Hui-Nan , Zhu Zhi-Yu , Wang Yue , Shi Chun-Wei , Wang Nan , Yang Gui-Lian , Wang Chun-Feng
Published: August 2022

Background: Trichinellosis is an important food-borne zoonosis, and no effective treatments are yet available. Nod-like receptor plays a critical role in the host response against nematodes. Therefore, we aimed to explore the role of the NLRP3 inflammasome (NLRP3) during the adult, migrating, and encysted stages of Trichinella spiralis (T. spiralis) infection. Methods: The mice were treated with the specific NLRP3 inhibitor MCC950 after inoculation with T. spiralis. Then, NLRP3 plays the role in T. spiralis-infected mice were evaluated using ELISA, Western blotting, Flow cytometry, Histopathological evaluation, Bone marrow-derived macrophage (BMDM) stimulation and immunofluorescenceResults: The in vivo results showed that NLRP3 enhanced the Th1 immune response in the adult stage and the migrating stage and weakened the Th2 immune response in the encysted stage. NLRP3 promoted the release of proinflammatory factors (INF-γ) and suppressed the release of anti-inflammatory factors (IL-4). Pathological changes were also improved in the absence of NLRP3 in mice during T. spiralis infection. Importantly, a significant reduction in adult worm burden and muscle larvae burden at 7 and 35 days post infection was observed in mice treated with the specific NLRP3 inhibitor MCC950. In vitro, we first demonstrated that NLRP3 in macrophages can be activated by T. spiralis proteins and promotes IL-1β and IL-18 release. Conclusions: This study revealed that the NLRP3 is involved in the host response to T. spiralis infection and that targeted inhibition of NLRP3 enhanced the Th2 response and accelerated T. spiralis expulsion. These findings may help in the development of protocols for controlling trichinellosis.
Infection by Aelurostrongylus abstrusus in a wild Leopardus wiedii (Carnivora: Felidae): case report
Authors: Ré Erickson Júnior De , Chafes Clóvis Junior Chimin , Possidonio Guilherme de Oliveira Alves , Bandiera Fernanda Canello , Buzatti Andréia , Preuss Jackson Fabio
Published: August 2022

Aelurostrongylus abstrusus, popularly known as “feline pulmonary worm”, it is a nematode that affects the respiratory system of felines causing aelurostrongylosis. This parasite can be found in the host’s bronchi and pulmonary arteries. The clinical signs presented vary according to the animal’s immune response and severity of the infection, the host might present apathy, dyspnea, syncope, wheezing, sneezing, among others. This report aims to describe a case of aelurostrostrilylosis in a feline of wildlife threatened of extinction. The animal, Leopardus wiedii (Schinz, 1821), popularly known as Margay, was found in an urban perimeter in the municipality of Anchieta, state of Santa Catarina (SC) in Brazil and attended at the Veterinary Clinic CLINIVET, of the University of the West of Santa Catarina - UNOESC, campus of São Miguel do Oeste (SC). In the initial clinical evaluation, the patient presented with deambulatory difficulties, biological samples were collected for further investigation. In the coproparasitological exam, parasitism was diagnosed by A. abstrusus, however the animal did not present any clinical signs related to the respiratory system. The results of this report indicate that the species L. wiedii, diagnosed with subclinical infection, can act as a wild reservoir for A. abstrusus, serving as a source of infection for other species of wild felids and also for domestic ones. This highlights the importance of effective public policies for the conservation, management and study of diseases that affect wild cats, especially species that need more urgent attention, that is, those threatened of extinction.
PERENCANAAN PERSEDIAAN PADA APOTEK X MENGGUNAKAN METODE EOQ
Authors: Sukmawati Anisya , Ramadhan Auditya Raihan
Published: August 2022

Persediaan barang dagang merupakan hal yang sangat penting bagi perusahaan dagang. Persediaan diperlukan untuk menciptakan penjualan dengan tujuan mendapatkan laba. Persediaan merupakan aktiva lancar yang memiliki resiko cukup tinggi dalam kegiatan perusahaan jika tidak perhatikan dengan benar maka resiko yang ditimbulkan dapat berupa resiko fisik dan resiko keuangan, misalnya dari segi fisik yaitu apabila terdapat kecurangan yang ada digudang karna kurangnya pengawasan dan adanya obat yang masuk ke masa expired mengakibatkan kerugiaan material karena harus membuang obat yang kadaluarsa dan mengakibatkan konsumen kecewa karena ketidak adaan barang yang dibutuhkan. Dan dari segi keuangan yaitu apabila terjadi kesalahan dalam pencatatan yang mengakibatkan kerugian perusahaan pada periode akuntansi.
RANCANG BANGUN APLIKASI PENGELOLAAN AKTIVITAS PROYEK (LOGBOOK APP) BERBASIS ANDROID DI PT. INKA MADIUN (PERSERO)
Authors: Widia I Dewa Made , Firmansyah Alfan
Published: August 2022

PT INKA (Persero) merupakan sebuah salah satu perusahaan BUMN yang bergerak dibidang Industri pembuatan transportasi kereta api. PT INKA (Persero) memiliki beberapa direktorat salah satunya adalah Direktorat Keuangan dan SDM yang di dalamnya terdapat beberapa divisi, salah satunya adalah adalah divisi keproyekan. Untuk memudahkan pengelolaan setiap aktivitas proyek divisi keproyekan menggunakan Project logbook. Project logbook berfungsi sebagai catatan aktivitas proyek Divisi Keproyekan selama project berlangsung dengan pihak lain. Pada saat ini Project logbook yang ada masih berbentuk draft dan arsip dokumen menjadi belum terorganisir dengan baik. Selain itu project logbook masih belum  terstandarisasi dengan baik sebagai contoh untuk aktivitas plan proyek masih berbentuk kertas, isu proyek masih belum realtime dalam penginformasian isu-isu yang ada dan project logbook masih belum mempunyai pelaporan data aktivitas proyek. Dengan dibangunnya sistem informasi ini diharapkan dapat membantu untuk mempercepat proses mengelola aktivitas-aktivitas proyek secara efektif dan efisien, membantu melihat aktivitas-aktivitas proyek secara real time dan dapat diakses dimanapun dan kapanpun serta membantu untuk pembuatan hingga pelaporan aktivitas-aktivitas proyek. Sistem informasi ini dirancang melalui tahapan perancangan menggunakan UML. Sistem informasi ini dibangun menggunakan framework Ionic dan database MySQL.
Automatic Wall Painter Using Raspberry PI
Authors: N Gurunath , D Lakshmi Narasima , A Kevin Anto , B Sushma , Babu Ambily
Published: August 2022

Abstract: This project describes development of Automatic Wall Painting Robot in real time which helps to achieve low-cost painting efficiently. It would offer the opportunity to reduce or eliminate human exposure to difficult and hazardous environments, avoids Human efforts, saves human life in risky painting like high rise buildings, which would solve most of the problems connected with safety when many activities occur at the same time. It will suit for all types of walls. The system performs the painting process using image captured by the pi camera. The painting area is calculated, and information is transferred to the spray gun. The whole process in painting is controlled by controlling circuit/Raspberrypi module. Raspberry pi module will control the DC motors, pully, paint spraying gun and connecting shaft. The pully will help in extending and retracting raises the connecting shaft and lowers it, respectively. The spray gun handle is mounted to the connection shaft, while the air compressor is set on the top platform and is turned ON/OFF at the bidding of the raspberry pi module
A Study on Awareness and Perception of Consumers towards GST with Special Reference to Restaurants in Bengaluru City
Authors: C Chittibabu , C Arun Kumar B.
Published: August 2022

Abstract: In India different kind of indirect taxes applied on goods and services by central and state government like Sales tax, VAT, Service tax, excise duty, entry tax etc., In the year 2017 Goods and Services Tax (GST) implemented all over the country with an intention of one nation, one tax and one market. The GST subsumed all the indirect taxes including taxes levied in restaurants like service tax, VAT etc. Taxes levied on services is a major contributor to government revenue. GST implementation has made an impact on consumers who pay taxes on services provided by restaurants. The objective of the study is to find out the level of awareness and perception of consumers on GST in restaurants. The study used descriptive research design. A sample of 100 consumers from different restaurants were randomly taken from the Bengaluru city. Both Primary and Secondary sources were used within the study. Data collected were analyzed by using frequency and percentages and findings are interpreted accordingly.
Online Examination Hall Seating Arrangement
Authors: Subhashini S , Sreerambabu Dr. J. , Riyaz M. Mohammed
Published: August 2022

Abstract: During examination time, it’s really agitated task to look out the venue of the examination hall which seat is assigned to selected student. Students used to face many problems for locating the examination hall and their seats. Therefore, an examination hall seating arrangement system is needed to computerize the conventional technique of preparing the examination hall allotment and generate the hall seating arrangement created automatically for sleek natural phenomenon of exams. The planned system will guide the student to look out their individual examination hall throughout their exams. This might in addition show the individual seat of a student in an extremely specific row of their examination. The other objective of developing this technique is to help the scholars to direct them to their individual examination hall whereas not delays for happening finding out hall created and their seat allotment. It contains the students, department, subject, staff details, examination hall and their seat allotment. This technique conjointly can send the hall selection and seat appointed to a selected student.
Epicardial Implantation of SelectSecure 3830 Lead in the neonate
Authors: Dong Zhenyu , Zhang Jiang-Hua , Ma Songfeng , Abdukadir Ablat , Tang Baopeng , Xu Yuanning
Published: August 2022

We present a case of epicardial pacemaker implantation in a low birth
weight newborn using the Model 3830. We found that the Model 3830
implanted in the epicardium can obtain superior pacing parameters, but
there is still need more evidence to support it.
Pannóniai klinotémák időrétegtana
Authors: Magyar Imre
Published: August 2022

Magyarországon a kronosztratigráfia tudománya az 1980-as és 1990-es évek során szembesült azzal a jelenséggel, hogy klinotémákkal kitöltött medencékben, mint amilyen a Pannon-tó medre is volt, Steno települési törvényei nem, vagy csak nagyon korlátozott értelemben érvényesek. A pannóniai emeletet nem eredetileg vízszintes, hanem dőlő, több száz méter vertikális kiterjedésű, klinoform geometriájú időrétegtani felületek tagolják. Szeizmikus értelmezéssel ezek a klinoformok leképezhetőek, kronosztratigráfiai korrelációjuk az endemikus élővilágra alapozott biokronológiai markerekkel valósítható meg, datálásuk pedig radiometrikus kormérésekkel és mágnesrétegtani értelmezéssel. A pannóniai klinotémákra kidolgozott időrétegtan modellként szolgálhat más nem-tengeri medencék kronosztratigráfiai tagolására a Paratethys-régióban és azon túl is.
Implante unitário de corpo único em zircônia em área estética – relato de caso
Authors: Carmo Filho Luiz Carlos , Novais Josuel , Macedo Rander Moreira , Spada Paula Porto , Sukekava Flavia
Published: August 2022

Zirconium dioxide implants, also called zirconia implants, have emerged on the market as a material option in rehabilitation with osseointegrated implants and their use has had an upward learning curve over the last few years. The aim of this study was to report a case in which an immediate single-body zirconia implant was used, associated with a subepitlhelial connective tissue graft, and immediate loading. The results showed totally adequate, from both a technical point of view and in terms of patient’s satisfaction. Clinical studies with long term follow-up are needed to further clarify the properties, advantages, and indications of zirconia implants
I väntan på integration: en etnografisk studie om en institutionellt återskapad vardagsverklighet
Authors:   , Raoof Dawan
Published: August 2022

Även om man inte känner till pjäsen eller till dess författare vet man antagligen att väntan på Godot anspelar på ett hopplöst tillstånd som hålls flytande genom illusionen av något hoppfullt. Studien handlar om en institutionellt återskapad vardagsverklighet på ett HVB-hem för ensamkommande barn och unga. Det övergripande syftet med denna fenomenologiskt orienterade studie är att åskådlig- och begripliggöra de institutionella villkor under vilka personalen förväntas realisera sitt integrerande samhällsuppdrag. Boendet är en institutionell scen. Ett antal individer – med vittskilda livshistorier – blir inkastade på denna scen för att tillsammans rekonstruera ett vardagligt meningssammanhang som i sig själv ska främja barnen och ungdomarnas integration i det svenska samhället. Allegoriskt uttryckt kan (föreställningen om) denna integration likställas med Godot. Ingen vet riktigt vem denna Godot är, om han kommer eller om han ens existerar. I sin frånvaro fyller Godot likväl en allsmäktig och messiansk roll för de inblandade aktörerna. Det är föreställningen om barnen och ungdomarnas integration som ger den institutionella tillvaron mening. Denna tillvaro koloniseras dock ständigt av olika institutionella faktorer som förvrider det mellanmänskliga meningsskapandet till något absurt. Denna avhandling är en etnografisk berättelse om det absurda i de institutionella villkor under vilka denna integrationsfrämjande vardagsverklighet återskapas
ANALISIS PERILAKU KONSUMEN MAHASISWI INSTITUT AGAMA ISLAM NEGERI PADANGSIDIMPUAN TERHADAP PEMBELIAN SUATU BARANG SECARA ONLINE
Authors: Permatasari Indah , Khairiyahtussolihah Assa'adatul , Fauzan Muhammad
Published: August 2022

In writing this journal, it aims to find out how the attitudes, behavior, and responses of females students in purchasing goods online. Many students make purchases online because they have a busy class time and don’t have free time to shop at supermarkets or markets. Many of the advantages the feel are easy, practical, can be done anytime, and anywhere. But there are also obstacles that they feel, namely they cannot bargain, cannot clearly know the quality of what they are buying, they can only see it through pictures or advertisments provided by the seller. They also get easy payments, such as paying after the goods are received (COD), if they don’t have they money they can do the installmen system.
COAL 2021: MODEL AND FORECASTS TO 2025 IN INDONESIA
Authors: Nasirin Wanda Khairun , Pane Mujahidun Hapisni
Published: August 2022

The problem with Indonesian coal is that the increase in coal demand is not accompanied by domestic coal production, because coal producers fail to meet the requirements of coal sales in the domestic market. This research purpose is to determine the model and prediction of coal production until 2025. Quantitative research using the autoregressive conditional heteroscedasticity (ARCH) method. The prediction results of the ARCH (2) model of coal production will still fluctuate until 2025.Keywords: Forecasting, Model, Coal, ARCH, GARCH
Influência da associação do ácido glicólico e microdermoabrasão sobre cicatrizes de acne e qualidade de vida em adultos jovens
Authors: Pinheiro Adriana Almeida , Santo Carina Teixeira do Espirito , Santos Jullyana Xáfira Rodrigues dos , Rocha Larissa Salgado de Oliveira
Published: August 2022

Objetivo: Verificar a influência da associação de peeling de ácido Glicólico e microdermoabrasão sobre as cicatrizes de acne na região facial. Métodos: O estudo foi realizado com adultos jovens, de ambos os sexos, de idade entre 24,69±4,28 anos com cicatrizes de acne do tipo ice-pick, submetidos à utilização do peeling de ácido Glicólico a 20% e do microdermoabrasão, durante uma vez por semana por 40 minutos, totalizando 4 sessões, sendo avaliados em dois momentos por imagens e pelo índice de Cardiff Acne Disability Index (CADI). Utilizou-se o teste de Shapiro Wilk, seguido de Teste T dados amostrais (p≤0,05). Resultados: Por meio de observação qualitativa, constatou-se que todos os participantes apresentaram melhora significativa no aspecto da pele, na aparência das cicatrizes e no controle da oleosidade. Conclusão: Foi possível perceber que a associação do microdermoabrasão com o ácido Glicólico tiveram resultados significativos na melhora da textura, hidratação, pigmentação, espessura da pele e controle da oleosidade, deixando as cicatrizes menos evidentes.
Synthesis and Structural Verification of an ArI(OTf)2
Authors: Dutton Jason , _ Tania , Sharp-Bucknall Lachlan
Published: August 2022

PhI(OTf)2 and related ArI(OTf)2 species have been incorrectly invoked as intermediates in oxidation reactions for many years. We recently established that such compounds did not yet exist but remain an attractive target. Here we describe the synthesis, isolation and structural characterization of NO2-PhI(OTf)2 which is resistant to decomposition, and also more reactive than PhI(OTf)(OAc), the species previously misidentified as PhI(OTf)2.
MANAJEMEN KEUANGAN MASJID MELALUI PEMBERDAYAAN EKONOMI
Authors: Asyidah Nur , Darwis Rahma Hidayati
Published: August 2022

Masjid pada umumnya digunakan sebagai fasilitas tempat ibadah, namun seiring berjalannya waktu kini masjid juga dapat membantu meningkatkan perekonomian masjid dan masyarakat sekitaran masjid.. Dengan manajeman keuangan yang baik bukan hanya meningkatkan nilai spiritual tapi juga menambah nilai ekonomi. Masjid Al-Markaz Al-Ma’arif merupakan salah satu masjid yang manajemen kuangannya baik. Ditandai dengan adanya usaha produktif yang dijalankan oleh pengurus masjid yang nantinya dapat berdampak positif terhadap pemberdyaan ekonomi masjid dan masyarakat sekitaran masjid. Penelitian ini bertujuan untuk menjawab rumusan masalah mengenai bentuk pemberdayaan ekonomi yang dikelola Masjid Al-Markas Al-Ma’arif, serta menganalisis manajemen keuangan masjid terhadap hasil pemebrdayaan ekonomi. Maka dari itu dilakukannya penelitian di Masjid Al-Markas Al-Markas Al-Ma’arif Kabupaten Bone sebagai objek penelitian, dan subjek penelitian di fokuskan pada pengurus masjid dan para pedagang diarea masjid. Penelitian ini berupa penelitian lapangan (Field Research) dengan pendekatan kualitatif deskriptif  menggunakan teknik pengumpulan data berupa wawancara, observasi lapangan dan studi dokumentasi. Dalam menganalisis data melalui teknik reduksi data, menyajikan data yang terpilih secara keseluruhan, kemudian menarik kesimpulan dari hasil analisis data yang diperoleh. Sehingga dari hasil penelitian ini pengurus masjid mampu mengelola keuangan masjid dengan baik melalui penyewaan kios dan penyewaan aula dengan memberdayakan jamaah masjid. hal ini mampu meningkatkan pendapatan masjid dan meningkatkan perekonomian jamaah masjid melalui usaha produktif yang dijalankan masjid. Untuk kedepan perlu pengembangan dan pengomptimalisasian manajeman keuangan masjid yang lebih intensif.
PENERAPAN AKAD IJARAH MUNTAHIYA BIT TAMLIK DALAM BANK SYARIAH
Authors: Al Usmaniyah Sirril Latifah
Published: August 2022

Bank syariah memiliki sistem menyalurkan dana dalam bentuk bisnis, bagi hasil dan kontrak. Kontrak disini  yang dimaksud adalah Ijarah, yaitu salah satu bentuk akad untuk memperoleh manfaat dari suatu barang dengan cara menggunakan jalur pengalihan (penjualan manfaat). Ijarah Muntahiya Bit Tamlik yaitu  macam- macam akad dari Ijarah yang mana sewa dengan diberi pilihan kepemilikan barang bagi pelanggan/nasabah. Pesatnya perkembangan perusahaan bank syariah saat ini mengakibatkan perusahaan bank syariah semakin kreatif. Bentuk kreatif  tersebut yaitu adanya akad baru, yaitu kesepakatan kontrak Ijarah Al Muntahiya Bit Tamlik (IMBT). Kontrak ini adalah gambaran dari kontrak campuran dan kesepakatan sewa barang diakhir masa sewa (perjanjian jual beli). Kontrak Ijarah Muntahiya Bit Tamlik merupakan inovasi baru yang dapat memberikan keringanan bagi masyarakat. Namun,kehadiran kontrak IMBT tengah diragukan para masyarakat. Penerapan akad Ijarah dalam urusan bisnis berupa persewaan tanah, bangunan, jasa, dan  lain-lain. Dalam urusan bisnis maupun urusan di bank syariah banyak terjadi permasalahan dengan akad Ijarah Muntahiya Bit Tamlik. Menanggapi permasalahan tersebut, jurnal ini secara khusus memberikan informasi berupa pengetahuan akad Ijarah Muntahiya Bit Tamlik  yang dilakukan di bank syariah.
ENSINO-APRENDIZAGEM SOBRE PERÍODOS CLÍNICOS E MECANISMOS DE PARTO:
Authors: Gonzaga Lima Beatriz , Alves Pereira Francisco Werbeson , Moreira Belém Jameson , De Melo Fialho Ana Virgínia , Ferreira da Silva Maria Rocineide , Vieira Pereira Emanuelly
Published: August 2022

Objetivo: Descrever a percepção de acadêmicos de Enfermagem sobre o processo ensino-aprendizagem de períodos clínicos e mecanismos de parto. Método: Pesquisa descritiva com abordagem qualitativa realizada com 12 acadêmicas de enfermagem recrutadas de forma aleatória mediante a utilização da técnica snowboll. no período de  março a junho de 2020 via Skype utilizando  entrevista semiestruturada. Os dados foram organizados em três categorias e realizou-se a análise categorial temática. Resultados: os achados evidenciaram que os discentes reconheceram suas próprias dificuldades relacionadas ao comprometimento, organização e corresponsabilidade em desenvolver estudos sobre a temática. Apontaram como principal limitação a desarticulação entre teoria e prática e como potencialidade a utilização de metodologias ativas. Enfatizaram a necessidade de articulação teórico-prática e ampliação de assuntos sobre a temática, mudanças nos recursos e estratégias pedagógicas, com vistas a favorecer a aprendizagem significativa e contribuir  para a oferta de cuidados obstétricos. Considerações finais: Conclui-se que o processo de ensino-aprendizagem sobre períodos clínicos e mecanismos de parto revela fragilidades relativas a forma de abordagem didática e dificuldades de assimilação dos conteúdos, dissociação teórico-prática, dificuldades de organização da rotina de estudos pelos discentes.