bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Processing Condition on the Yield of Oscimum Gratissimum Extract
Authors:   Dept. of Bioprocess and Polymer Engineering, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia, Rasit Farah Ashikin , Sakinah Marzuki Nurul Farahin ,   Dept. of Bioprocess and Polymer Engineering, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia, Abd Aziz Nur Amanina ,   Dept. of Bioprocess and Polymer Engineering, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia, Mohd Said Mazlina ,   Drug and Herbal Research Centre, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia, Asis-Enriquez Ma. Louisa De ,   Center for Natural Science and Environmental, Research (CENSER), College of Science, De La Salle University, Manila, 1004 Metro Manila, Philippines, Hasham @ Hisam Rosnani ,   Institute of Bioproduct Development (IBD), Universiti Teknologi Malaysia, 81310 Johor, Malaysia
Published: April 2023

Ocimum gratissimum (O. gratissimum) is a medicinal plant which native in Southeast Asia. Containing various compound with medicinal value, it acts as herb and spices in cooking, perfumery and used in traditional preparation. It is reported that O. gratissimum has many phenolic compounds which responsible for many biological activities such as eugenol, limonene, ocimene and rosmarinic acid. Scientific studies regarding O. gratissimum are widely known due to its beneficial therapeutic properties, such as antioxidant, antibacterial, anti-inflammatory and others. However, different extraction techniques approaches will give different effects on extraction yield of bioactive compounds according to the processing condition such as solvent polarity, concentration of solvent, temperature and solvent to sample ratio that applied. This study applied Soxhlet and Ultrasonic-assisted Extraction (UAE) techniques to determine the extraction yield of O. gratissimum. The results indicated Soxhlet techniques requires 2 hours, sample to solvent ratio; 1:10 and temperature at 60oC to obtained highest yield of O. gratissimum extract with percentage yield at 1.723% compared to others processing conditions. Meanwhile, UAE techniques showed highest yield of O. gratissimum extract at sample to solvent ratio at 1:10 with results 20.60% and 60% Methanol as the best solvent for extraction. Throughout analysis, UAE techniques was chosen as the methods of extraction for O. gratissimum with processing conditions that gives high yield of extraction.
Molecular markers as predictors of response to perioperative chemotherapy in locally advanced gastric cancer
Authors: Oganyan K. A. , Musaelyan A. A. , Lapin S. V. , Kupenskaya T. V. , Sveсhkova A. A. , Belyaev M. A. , Zakharenko A. A. , Orlov S. V.
Published: April 2023

Introduction. Perioperative FLOT chemotherapy has improved prognosis in patients with locally advanced resectable gastric cancer (GC). However, in 80 % of cases, the tumor is resistant to the therapy, resulting in unnecessary toxicity and delayed surgical treatment.

Aim. Evaluation of clinico-morphological patterns of microsatellite instability, HER2 gene amplification, changes in gene copy number and their relationship with the response to perioperative FLOT chemotherapy in patients with locally advanced resectable GC.

Materials and methods. The retrospective study included 185 patients. All tumor samples were assessed for HER2 and microsatellite instability status. Among all cases there were 45 patients with locally advanced T2–4N1–2 M0 GC, who underwent a total or subtotal gastrectomy with D2 lymphadenectomy and perioperative chemotherapy with FLOT. Microsatellite instability detection was performed using fragment analysis, HER2 gene amplification testing – fluorescent in situ hybridization. Also 19 patients were tested for copy number changes of the FGFR1, FGFR2, KRAS, MET, EGFR, CCND1, MYC genes using Multiplex ligation-dependent probe amplification. The endpoints were progression-free survival and objective response rate.

Results. Microsatellite instability was detected in 4.8 % (9/185) of GC cases. Microsatellite instability was associated with advanced age (p = 0.005), low grade of differentiation (p = 0.011), presence of tumor-infiltrating lymphocytes (p = 0.0004), and high preoperative CA 72–4 levels (p = 0.025). Prevalence of HER2 amplification was 7.5 % (14/185). It was associated with low grade of differentiation (p = 0.048) and metastasis in regional lymph nodes (p = 0.037). PFS in patients with HER2-positive (HER2 – human epidermal growth factor receptor 2) GC treated with perioperative FLOT chemotherapy (4/45) was significantly lower than in patients with HER2-negative GC: the median was 156 and 317 days, respectively (hazard ratio 0.49; 95 % confidence interval 0.16–1.47; p = 0.0006). There was no correlation between the presence of the alteration and ORR (p = 1.0). Progression-free survival in GC patients with KRAS amplification (3/19) was significantly lower comparing with patients without it: the median was 98 and 327 days, respectively (hazard ratio 0.29; 95 % confidence interval 0.07–1.19; p <0.0001). There was no association between an increase in KRAS copy number and objective response rate (p = 1.0). For microsatellite instability and other studied markers no statistically significant correlation with progression-free survival and objective response rate was found (p >0.05).

Conclusion. The presence of HER2 and KRAS amplification have been shown as promising predictive markers of the treatment failure in patients treated with perioperative FLOT chemotherapy for locally advanced resectable GC.
A Touching Relationship
Authors:   , Falk Lynn A. , Devereaux Christina
Published: April 2023

The sense of touch holds a unique role in creating, communicating, and forming social bonds. The American Dance Therapy Association (ADTA) has formally embraced the potential therapeutic benefits of touch such as safety, comfort, pain relief, grounding, bodily integration, awareness, regulation, and social connection while setting clear guidelines to mitigate its risks. Touch is also woven into the fabric of Western medicine through procedures or tasks and less often as a means of comfort. This project consists of a literature review and a journal article manuscript exploring the communicative role of touch within dance/movement therapy (DMT) near the end of life. A review of literature includes the neuroscience of interpersonal touch, the role of touch in human development across the lifespan, touch as nonverbal communication, attitudes toward touch in health care, touch in the context of COVID-19, and the ethics and use of touch in dance/movement therapy. The journal article manuscript is a narrative case description highlighting the communicative role of touch in dance/movement therapy near the end of life with a 66-year-old Caucasian, female with Glioblastoma Multiform, a terminal brain cancer, her 34-year-old daughter, and spouse. This project aims to demonstrate the importance of touch in nonverbal communication, the need for communication and connection near the end of life, and the ability of dance/movement therapists to encourage and facilitate these social and emotional connections through touch.
He wahine māia, he wahine toa: A Gathering of Reflections on the Work of Haunani-Kay Trask
Authors: Greensill Hineitimoana , Prendergast Sam Iti , Ieremia-Allan Wanda , Taito Mere
Published: April 2023

In 1985, Haunani-Kay Trask visited Aotearoa contributing critical perspectives to a Pacific studies conference at the University of Auckland. Observing the disturbing absence of Indigenous women speakers at the conference, Dr. Trask finished her keynote early, giving her remaining time to two Māori women, Atareta Poananga and Titewhai Harawira. As a group of Indigenous Pacific women negotiating our own place in the academy, this conscious political act is one of many forms of Haunani-Kay Trask’s activism that has inspired us. From various parts of Te Moana Nui a Kiwa, we come together to weave stories of our engagements in the intellectual and activist work of Haunani-Kay Trask. In distinctive ways, we acknowledge Dr. Trask’s legacy and reflect on the inspiration and insight that her work has provided for us as Native daughters of the Pacific and as emerging scholars. Drawing on our own unique sea, land, and skyscapes, our histories of colonialism and resistance, and our creative and intellectual journeys, we share the multiplicity of ways in which Haunani-Kay Trask’s work speaks to our hearts and minds. Reflecting on her work as a scholar, poet, and activist, we weave together our words of respect, love, and admiration, and we consider the ways in which her scholarship continues to have ongoing relevance to us all.
The Slyly Reproductive Lessons of Haunani-Kay Trask
Authors: Vaughn Kēhaulani
Published: April 2023

Haunani-Kay Trask’s theorizations of settler colonialism, Indigenous feminisms, and community-grounded political work produces scholars, thinkers, and activists, including many Hawaiians, other Pacific Islanders, and Indigenous peoples of Turtle Island. Her teachings and work with Ka Lāhui Hawai‘i emphasized the need to build relationalities among Indigenous communities. This essay builds on Trask’s critical interventions and theorizations of settler colonialism, to ask how Hawaiians at home and in the diaspora can further Trask’s scholarship and political organizing, incorporating trans-Indigenous recognitions. I document these relationalities among Native nations and other Pacific Islanders as an embodiment of the legacies of Haunani-Kay Trask, including her theorization of settler colonialism and the groundwork she laid for Indigenous feminism. In this way, I link her teachings as slyly reproductive at creating generative futures beyond the settler state.
Design music games based on the play of folk games to create excitement for preschool children 5 – 6 years old
Authors: Le Thu Trang
Published: April 2023

In music teaching for kindergarten, music gaming is an attractive activity and is deeply loved by children. It's not only a natural way to remind musical knowledge learned but also helps them to be self-confident, more active, and have good teamwork technic. At present, there is limited in new planning and building new games for teachers besides some guides in the modal schedule. The music games were old and repeatedly played which doesn't attract children anymore. In addition, we are in the 4.0, the folk things, especially folk games are nearly replaced by modern Internet games. This one has rules and steps to build the music games Bayon the folkgames that children will pay more attention to and get more attractively in the music games.
Applying steam education in inclusive education: opportunities and challenges
Authors: Hoang Thi Nga , Nguyen Thi Ngoc Nga
Published: April 2023

Inclusive education has been proven as an educational approach that gives children with disabilities the best opportunity to develop their potential in an equitable and progressive manner. However, research studies on the importance and effectiveness of STEAM education application in inclusive education for children with disabilities are still less compared to the requirements needed in the reality. The article points out the opportunities and challenges of applying STEAM education in inclusive education for children with disabilities, as a theoretical basis for more specific research on this issue.
A CONCEPÇÃO DE DESENVOLVIMENTO NO SISTEMA PSICOLÓGICO-DIDÁTICO ELKONIN-DAVIDOV-REPKIN
Authors: Puentes Roberto Valdés
Published: April 2023

O artigo aborda a aprendizagem desenvolvimental na perspectiva do sistema psicológico-didático Elkonin-Davidov-Repkin. No geral, as pesquisas brasileiras sobre a temática baseiam-se na análise da função e conteúdo dessa teoria e, sobretudo, de sua atividade de estudo, entretanto a própria concepção de desenvolvimento humano que a mesma pretende tem sido ignorada ou pelo menos negligenciada. O presente artigo aborda três aspectos: 1) o tipo de desenvolvimento que o sistema adota como objetivo; 2) as dimensões cognitiva e subjetiva do desenvolvimento psíquico; 3) o desenvolvimento da personalidade e sua periodização. Do ponto de vista metodológico, o artigo, por um lado, situa o estudo do desenvolvimento no contexto das possibilidades de sua periodização, mas foca-se apenas na análise de um período específico (atividade de estudo); por outro, trata o objeto a partir de uma abordagem analítica e interpretativa, pois em lugar de apresentar simplesmente o conteúdo da teoria em questão, constrói interpretações hipotéticas a partir dela e deduz, infere, abstrai, reflete, compara, argumenta, tendo um problema novo como foco de estudo.
TEORIA DO ENSINO DESENVOLVIMENTAL NA RÚSSIA E NO BRASIL
Authors: Libâneo José Carlos , Chudinova Elena V. , Cunha André Luiz Araújo
Published: April 2023

Session Thematic Articles Presentation Vol 25, n.1, 2022
EDITORIAL
Authors: Freitas Raquel A. Marra da Madeira
Published: April 2023

Editorial do Volume 25 (2022)
OS IMPASSES DA REPÚBLICA E A BREVE DÉCADA DE 1920: INTELECTUAIS E OPERADORES DO ESTADO NAS REFORMAS EDUCACIONAIS NO BRASIL
Authors: Santos Lincoln de Araújo
Published: April 2023

O trabalho discute os sentidos das reformas educacionais ocorridas nos anos 1920, percebendo sua importância em tempo marcado por crises institucionais. Tomando por base intelectuais brasileiros e operadores do Estado, analisa iniciativas voltadas a estabelecer projetos educacionais com inspiração liberal-escolanovista, num contexto de federalismo autoritário que mantém, todavia, relações locais e oligárquicas. O debate se dá sobre o período ao identificar movimentos de cunho social e cultural organizados com autonomia ao Estado. A educação irrompe o ideário liberal.
THE EFFECT OF ANTERIOR INTERBODY CAGE BORON APPLICATION IN RABBIT VERTEBRAE ON BONE FUSION AND FUSION QUALITY
Authors: Korkmaz Serhat , Karabekir Hamit Selim
Published: April 2023

OBJECTIVE: Our aim in this study was to demonstrate the effectiveness of hydroxyapatite (HA) and Boron compounds in operations using an Anterior Lumbar Interbody Fusion (ALIF).
MATERIAL AND METHODS: In the study, 18 male rabbits of New Zealand breed weighing 2.5-3 kg were used. The animals who were hospitalized on the left side underwent flank incision after surgical cleaning. Lumbar 5-6 distance was reached from the lumbar retroperitoneal region. Following anterior discectomy; ALIF was performed using PEEK (polyethylene ether ketone) cage (Group I) in the control group, PEEK cage and 50 mg/kg boron (borax pentahydrate) (Group II) in the boron group, PEEK cage and 50 mg/kg powder ProOsteon (Group III) in the HA group. The ALIF operation has been applied to all groups. Six weeks later, the animals underwent a computed tomography (CT) scan. Then the lower and upper vertebrae of the sacrificed animals at the distance at which discectomy was performed and the cage was placed were removed, separated for pathology. After being microscopically detected with buffered 10% formaldehyde overnight, the sections prepared from the sample tissues that were routinely followed were stained with hematoxin-eosin and examined histopathologically with light microscopy.
RESULTS: While the osteoclast score was 1 in 83.3% of the boron group, it was 2 in 16.6%. In the same group, the osteoblast score was found to be 1 in 50% and 2 in 50%. The osteoclast score of the HA group was 1 in 50%, 2 in 50%, while the osteoblast score was found in 50%, 1 in 2, 2 in 16.6%, and 3 in 33.4%. Higher osteoblast and osteoclast scores were observed in HA group compared to Boron and control groups. It was observed that the boron group had higher osteoblast and osteoclast scores than the control group and lower than the HA group.
CONCLUSIONS: Boron and Hydroxyapatite have been shown to form stones of the same size. Although morphologically not as much as boron, hydroxyapatite, histopathological examination showed that it formed a better amount of fusion compared to the control group. The osteoblastic activity was most common in the hydroxyapatite group.
CANLI BÖBREK DONÖR VARYASYONLARININ ÇOK KESİTLİ BİLGİSAYARLI TOMOGRAFİ İLE PREOPERATİF DEĞERLENDİRİLMESİ VE SONUÇLARIN İNTRAOPERATİF BULGULAR İLE KARŞILAŞTIRILMASI
Authors: Sever İbrahim Halil , Mammadov Tural , Barlas İlhami , Özkul Bahattin , Koyuncu Sökmen Bedriye , Yılmaz Fatma , Atan Uçar Zuhal , Sinangil Ayşe , Akin Emin Barış
Published: April 2023

AMAÇ: Bu çalışmayla, çok kesitli bilgisayarlı tomografi (ÇKBT) kullanarak canlı böbrek donörlerinde renal vasküler ve toplayıcı sistem varyasyonlarını değerlendirmek ve verileri retroperitonoskopik donör nefrektomisinde saptanan bulgular ile karşılaştırmak amaçlanmıştır.
GEREÇ VE YÖNTEM: Çalışmaya, Ocak 2015 ile Ekim 2021 arasında merkezimizde retroperitonoskopik donör nefrektomisi olan ve operasyon öncesi uygun protokol ile gerçekleştirilmiş ÇKBT görüntülemesi mevcut olan 652 donör dahil edildi. Böbreklerdeki arteryel, venöz ve toplayıcı sistem varyasyonları ÇKBT incelemesiyle değerlendirilip not edilerek sonuçlar operasyon bulguları ile karşılaştırıldı.
BULGULAR: Donörlerin %72,7’sine (474 kişi) sol nefrektomi, kalan 178 donöre (%27,3) ise sağ nefrektomi yapıldı. Nakledilen 652 böbreğin 99’unda (%15,1) çift arter, 11’inde (%1,6) üç arter ve 1’inde (%<1) dört arter mevcut iken; 14 (%2,1) böbrekte erken arteryel segmentasyon saptandı. Laparoskopik bulgulara göre 26 (%4) donör böbrekte çift renal ven, 3 (%0,4) böbrekte üç adet renal ven mevcut iken; 8 donörde yapısal venöz varyasyon ve 6 donörde toplayıcı sistem varyasyonu görüldü. Aksesuar arter varlığını saptamada, ÇKBT’nin duyarlılık, özgüllük, pozitif-negatif öngörü değeri ve doğruluk oranları sırasıyla %97,3; %98,5; %93,1; %99,4 ve %98,3 olarak bulundu. Arter sayılarını saptamadaki doğruluğu ise %98 olarak hesaplandı. Venlerdeki sayısal varyasyonu saptamada ÇKBT’nin duyarlılık, özgüllük, pozitif-negatif öngörü değeri ve doğruluk oranları sırasıyla %100; %99,8; %96,5; %100 ve %99,8 olarak bulundu. Ven sayılarını saptamadaki doğruluğu ise %99,8 olarak hesaplandı. Arteryel erken segmentasyon, geç venöz konfluens ve toplayıcı sistem varyasyonlarını tespit etmede ise %100 başarı sağlandı.
SONUÇ: Doğru teknik ile gerçekleştirilen ÇKBT, canlı donör böbrek nakli için donör adaylarında renal vasküler ve toplayıcı sistem varyasyonlarının değerlendirilmesi için oldukça doğru bir yöntemdir.
COVİD 19 NEDENİYLE ÖLEN HASTALARIMIZIN KLİNİK ÖZELLİKLERİ
Authors: Taşkıran İmren , Şan Yosun , Turken Melda , Ersan Gürsel , Köse Şükran
Published: April 2023

AMAÇ: Tüm dünyanın yeni karşılaştığı ve hızla dünyayı etkisi altına alan koronavirüs hastalığı 2019 (COVID-19), 11 Mart 2020‘den itibaren Türkiye’de ilk vakanın görülmesi ile birlikte ülkemizde de hızla yayılmaya başladı ve beraberinde ölümleri de getirdi. Çalışmamızda bir yıllık süre içinde hastanemizde yatarak takip ettiğimiz ve mortal seyreden COVID-19 tanılı olguların demografik verileri, klinik ve laboratuvar değerlendirilmesi ve mortalite oranlarının irdelenmesi amaçlanmıştır.
GEREÇ VE YÖNTEM: 11.03.2020 - 31.03.2021 tarihleri arasında hastanemizde COVID-19 tanısı ile takip edilen 3650 olgunun hasta dosyaları incelendi. Mortal seyreden olgular değerlendirildi.
BULGULAR: Pandemi sürecinde bu dönemdeki hastanemizde COVID-19 tanısı ile servis ve yoğun bakımda takip edilen toplam 3650 hastada mortalite oranı % 11,3’tür. Çalışmaya dahil edilen 406 hastanın 255’i (%62,8) erkek ve ortanca yaş 72 (18-106) olarak saptandı. En fazla eşlik eden kronik hastalıklar 141 (%34,7) hastada hipertansiyon, ikinci sırada ise 113 (%27,8) hastada kronik böbrek hastalığıydı. Başvuru anında en sık görülen semptomun dispne (%57,6) olduğu gözlendi. Hastaların başvuru tetkiklerindeki ortanca d-dimer değeri 1955 ng/mL (40-25810) , ortanca ferritin değeri de 450 ng/mL (9-10157) olarak hesaplandı. Hastalarımızın 237 (%94) ‘sinin toraks bilgisayarlı tomografi görüntüleri COVID-19 pnömonisi ile uyumlu raporlandı.
SONUÇ: Çalışmamızda pandemik seyir gösteren COVID-19 hastalığı nedeniyle mortal seyreden olgularımız irdelenmiş; erkek cinsiyet, ileri yaş, hipertansiyon ve kronik böbrek hastalığı olan hastaların, COVID-19’dan ölen hastaların içinde yüksek oranda bulundukları gözlemlenmiştir.
YOĞUN BAKIMDA ÇALIŞAN SAĞLIK PERSONELİNDE TÜKENMİŞLİK DÜZEYİNİN SOSYODEMOGRAFİK DEĞİŞKENLERLE İLİŞKİSİ
Authors: Yıldırım Özgür Deniz , Sıvacı Remziye , Taşdemir Mecit Bilge Banu , Doğan Bakı Elif
Published: April 2023

AMAÇ: Çalışmamız Afyonkarahisar Sağlık Bilimleri Üniversitesi yoğun bakım ünitelerinde çalışan sağlık personelinin tükenmişlik düzeyinin sosyodemografik değişkenlerle ilişkisini belirlenmeyi ve ardından bu soruna çözüm önermeyi amaçlamıştır.
GEREÇ VE YÖNTEM: Öğretim üyesi, uzman doktor, asistan doktor ve hemşireler dahil toplam 145 yoğun bakım çalışanına 18 sorudan oluşan sosyodemografik veri formu ve 22 sorudan oluşan Maslach tükenmişlik ölçeği’ni içeren iki bölümlü anket uygulandı. Anket uygulaması sonucu elde edilen verilerin istatiksel analizi SPSS (Statistical Package fort the Scocial Science Version 20, Chicago, ABD) programı kullanılarak yapıldı.
BULGULAR: Yoğun bakım çalışanlarının Maslach tükenmişlik ölçeği duygusal tükenme puan ortalaması 18.26±7.61, duyarsızlaşma boyutu puan ortalaması 8.42±2.96 olarak, kişisel başarı hissi puan ortalaması ise 10.64±4.15 olarak bulunmuştur.
SONUÇ: Yoğun bakım çalışanlarının duygusal tükenme ve duyarsızlaşma alt ölçeği ortalama puanlarına göre orta düzeyde tükenmişlik yaşadığı bulundu. Yoğun bakım çalışanlarının yaşadığı tükenmişlik sendromu açısından personelin sorunlarının tespiti, düzeltiltici çalışmaların yapılması ve anketin belli aralarla tekrar edilmesinin faydalı olacağı kanaatindeyiz.
PROLIDASE ACTIVITY AND OXIDATIVE STRESS IN BENIGN, PRE-MALIGNANT AND MALIGNANT ENDOMETRIAL LESIONS
Authors: Köse Mesut , Vurmaz Ayhan , Çelik Yasemin
Published: April 2023

OBJECTIVE: The present study aims to investigate the prolidase activity, total oxidant status (TOS) and total anti-oxidant status (TAS) in women who have been diagnosed with benign, pre-malignant and malignant endometrial pathologies.
MATERIAL AND METHODS: Ninety women who underwent endometrial biopsy due to abnormal uterine bleeding were divided into three groups according to their histopathological findings: Benign endometrial pathology (n=65), endometrial hyperplasia (n=12) and endometrial cancer (n=13). These groups were compared with respect to oxidative stress markers and prolidase activity in serum and endometrial tissue.
RESULTS: When compared to the benign endometrial pathology group, the endometrium cancer group had significantly higher age, shorter height and higher incidences of menopause and positive family history for gynecological malignancy (p=0.001, p=0.023, p=0.001 and p=0.001). When compared to the benign endometrial pathology group, tissue prolidase activity was significantly higher in the endometrium hyperplasia and endometrium cancer groups (p=0.001 for both). However, tissue prolidase activity was statistically similar in the endometrial hyperplasia and endometrial cancer groups (p=0.166). All study groups had statistically similar serum prolidase activity, serum and tissue TOS, serum and tissue TAS, tissue malondialdehyde and glutathione values.
CONCLUSIONS: Prolidase activity in endometrial tissue has enhanced in pre-malignant and malignant endometrial lesions when compared to benign endometrial lesions. The assessment of prolidase activity in endometrial tissue might help to distinguish pre-malignant and malignant lesions in case histopathological characteristics are insufficient for the differentiation of endometrial lesions.
ABDOMINAL WALL SCAR ENDOMETRIOSIS AFTER CESAREAN SECTION; A RARE CASE REPORT WITH MULTI FOCUS
Authors: Atıgan Ayhan , Kılıç Derya , Arman Karakaya Yeliz , Güler Ömer Tolga
Published: April 2023

Endometriosis is described as the presence of functional endometrial tissue outside the uterine cavity. Scar endometriosis (SE) is a rare condition which usually develops after gynecologic operations involving the uterus and fallopian tubes. The symptoms are usually nonspecific and cyclic incisional pain increasing by menstruation is the most common symptom. Diagnosis of the disease can be difficult and may be confusing with various other post-surgical conditions. Histopathological examination reveals the final diagnosis. This article presents a case with cesarian SE of which the largest reaches 5x4x3 cm with multiple foci. Scar endometriosis should be considered in the differential diagnosis of abdominal wall masses in the patients with a history of abdominal surgery and cyclic painful solid mass.
Is the tactical treatise of Dionysius Longinus a historical fact or historiographical myth?
Authors:   Belgorod National Research University, Nefedkin Alexander K.
Published: April 2023

It could think that there were no “Tactics” in the works of the an-cient Greek rhetorician Longinus. Most likely, an anonymous military treatise under the descriptive title “De aciebus bellicis” was in the inventory used by the Swiss polymath Konrad Gesner, who considered this work to be a writing of Dionysius Longinus. Except in “Bibliotheca” by K. Gesner, this reference did not occur anywhere; there are no any traces of this treatise in historiog-raphy.
Burnout among Military Personnel: A systematic Review
Authors: Hosseini Seyed Morteza , Hesam Saeed , Hosseini Seyed Amirhossein
Published: April 2023

Objective: Burnout is a psychological symptom characterized by emotional exhaustion, depersonalization, and lack of personal accomplishment. Several systematic reviews have examined the prevalence of burnout in some communities, including the communities of physicians, nurses, students, and teachers. Risk factors, consequences of burnout, and related interventions have also been evaluated in several systematic review studies. The purpose of this systematic review was to investigate the prevalence, risk factors, consequences, and interventions associated with burnout among military personnel in all types of studies.
Method: Studies that quantitatively examined burnout in military personnel after 2000 were identified through systematic searches in PubMed, Scopus, Web of Knowledge, Embase, PsychInfo, and PsycArticles databases.
Results: A total of 43 studies met the criteria for inclusion in this systematic review. Of these, 34 were cross-sectional, 7 were longitudinal, 1 was case-control and 1 was experimental. Half of the studies had more than 350 samples. The studies were from 17 different countries, among which the United States had the largest number with 17 studies. 33 studies were measured with one version of Maslach Burnout Inventory (MBI). Totally, only 10 studies reported a prevalence of burnout and/or its subscales. The prevalence of high emotional exhaustion ranged from 0% to 49.7% (median 19%), the prevalence of high depersonalization ranged from 0% to 59.6% (median 14%) and the prevalence of low personal accomplishment ranged from 0% to 60% (median 6.4%). In this systematic review, work environment factors (such as workload, shift work), psychological factors (anxiety, depression, stress), and duration and quality of sleep were shown as risk factors of burnout or its subscales. Also, psychological distress was observed as the consequence of burnout in more than one study.
Conclusion: The studies investigated in this systematic review showed a relatively moderate prevalence of burnout. In fact, burnout was associated with work environment factors and psychological variables.
An Overview of Bipolar Disorder Diagnosis Using Machine Learning Approaches: Clinical Opportunities and Challenges
Authors: Campos-Ugaz Walter Antonio , Palacios Garay Jessica Paola , Rivera-Lozada Oriana , Alarcón Diaz Mitchell Alberto , Fuster-Guillén Doris , Alfonso Tejada Arana Arístides
Published: April 2023

Objective: Automatic diagnosis of psychiatric disorders such as bipolar disorder (BD) through machine learning techniques has attracted substantial attention from psychiatric and artificial intelligence communities. These approaches mostly rely on various biomarkers extracted from electroencephalogram (EEG) or magnetic resonance imaging (MRI)/functional MRI (fMRI) data. In this paper, we provide an updated overview of existing machine learning-based methods for bipolar disorder (BD) diagnosis using MRI and EEG data.
Method: This study is a short non-systematic review with the aim of describing the current situation in automatic diagnosis of BD using machine learning methods. Therefore, an appropriate literature search was conducted via relevant keywords for original EEG/MRI studies on distinguishing BD from other conditions, particularly from healthy peers, in PubMed, Web of Science, and Google Scholar databases.
Results: We reviewed 26 studies, including 10 EEG studies and 16 MRI studies (including structural and functional MRI), that used traditional machine learning methods and deep learning algorithms to automatically detect BD. The reported accuracies for EEG studies is about 90%, while the reported accuracies for MRI studies remains below the minimum level for clinical relevance, i.e. about 80% of the classification outcome for traditional machine learning methods. However, deep learning techniques have generally achieved accuracies higher than 95%.
Conclusion: Research utilizing machine learning applied to EEG signals and brain images has provided proof of concept for how this innovative technique can help psychiatrists distinguish BD patients from healthy people. However, the results have been somewhat contradictory and we must keep away from excessive optimistic interpretations of the findings. Much progress is still needed to reach the level of clinical practice in this field.
Polyurethane and rare-earth materials: a review
Authors: Pegoraro Guilherme Manassés , Alves Lucas Repecka , Carriello Giovanni Miraveti , Janolla Thais de Agrella , Mambrini Giovanni Pimenta , Rezende Maira de Lourdes , Menezes Aparecido Junior de
Published: April 2023

Polyurethanes are polymers produced from polyols and isocyanates. Commonly, aiming to modify physicochemical properties of the resulting material, other chemical species can be introduced in the polymeric structure, modifying its mechanical, thermal and electronic characteristics and conferring more stability and resistance to external factors. The rare earth chemical elements, composed of lanthanides, Y and Sc, can give the materials such improved characteristics, and are still less researched when compared to other chemical elements. In the present study, a systematic search was carried out on the Web of Science platform. No studies were identified with polyurethanes and Sc, Pr, Pm, Sm, Dy and Ho, showing room for unexplored studies. Most of the articles investigated the luminescent characteristics of the chemical elements that were used, but it was also possible to notice trends in changing mechanical and thermal properties.
Transmedialidad y alternativas representacionales en la obra de Martín Rejtman
Authors: Herrero Mariela
Published: April 2023

Parto de la premisa —vastamente revisada— de que las formas de representar, o más específicamente, los mecanismos de representación literaria, son «historizables»; esto es, que no pueden entenderse como estructuras rígidas e incuestionables, sino que más bien responden a las variaciones y cambios de la realidad social de la que se pretenden expresión. Siguiendo esta línea y tomando como eje el impacto de la tecnología, puntualmente del nuevo cine argentino, propongo analizar en la obra de Martín Rejtman de qué manera incide la representación cinematográfica en la literatura, es decir, en qué medida el cruce y la contaminación de estos lenguajes y medios puede leerse como una alteración de los paradigmas tradicionales de representación. Se trata no solo de analizar qué intercambios se producen entre un lenguaje y otro, sino sobre todo de revisar los procedimientos que en continuidad y reciprocidad permiten explorar, en su obra, una vía para el realismo que, lejos de agotarse en la mera transposición o reescritura, posibilita pensar en una reformulación del sistema narrativo, tanto literario como cinematográfico. Partiendo de su última película coescrita y dirigida con Federico León, Entrenamiento elemental para actores, y haciendo una lectura en paralelo con su versión «novelada», busco revisar su obra conjunta para ampliar los análisis que dan cuenta de la imbricación o determinación del lenguaje literario y cinematográfico como variante o alternativa a las formas tradicionales de representación.
Avatares de la rareza. «Cornelia frente al espejo», entre la literatura y el cine
Authors: Biancotto Natalia
Published: April 2023

La aparición de la película Cornelia frente al espejo (2012), de Daniel Rosenfeld, basada en el cuento homónimo de Silvina Ocampo, interroga sobre las posibilidades de transponer la extrañeza de este relato al lenguaje fílmico. La hipótesis que guía este trabajo propone que la película compone, a partir del cuento de Ocampo, otro relato diverso, en el que se ponen de manifiesto relecturas y desvíos de la rareza ocampiana. A pesar de mantener los diálogos originales del cuento, esta versión cinematográfica diverge de él, especialmente, en el tono de la narración, en función de lo que considero es un efecto de lectura provocado por la extrañeza del cuento. Mientras que en Ocampo las formas del nonsense organizan el relato, la reinterpretación que el filme pone en escena se enmarca en el horizonte de lecturas que vinculan esta narrativa con el absurdo.
Intermediación y diálogo cultural entre las reinas del sur
Authors: Molina Luis
Published: April 2023

Este artículo propone un acercamiento intermedial entre dos textos homónimos, titulados La reina del sur; uno literario (2012) y el otro audiovisual (2012). Para ello abordará la propuesta de cada uno en relación con sus propios antecedentes históricos y culturales. Luego realizará una lectura comparativa de ambas obras para observar las fuentes, el impacto y sus diálogos interculturales transatlánticos que surgen de la adaptación. El texto se enfoca en la manera que el video musical selecciona y construye su independencia narrativa del texto literario.
Del guion a la novela : la construcción de la mirada de los hijos en Kamchatka
Authors: Paz-Mackay María Soledad
Published: April 2023

El filme Kamchatka (Piñeyro, 2002) aborda la memoria de la última dictadura militar argentina desde la mirada infantil. La novela del mismo título (Figueras, originalmente publicada en 2003), presenta un interesante caso de análisis pues fue escrita a partir del guion. La diferencia esencial entre ambas es el punto de vista de la narración. Mientras que el filme representa el recuerdo de un niño que acompañó a su familia en el paso a la clandestinidad, la novela introduce uno de los primeros ejemplos del hijo de desaparecidos como figura literaria al ser narrada por el mismo personaje, quien ya adulto se refiere a los eventos de su infancia después de treinta años.
El Templo del Sol Coricancha en Cusco y Vilcabamba
Authors: Sakai Masato
Published: April 2023

En el presente ensayo hemos escogido las dos capitales de los incas —Cusco y Vilcabamba— con el fin de aclarar bajo qué normas se erigió el Templo del Sol o Coricancha ubicado en cada una de las capitales.
Recursos naturales, medio ambiente y desarrollo : Perú 1970-2010
Authors: Glave Testino Manuel , Barrantes Cáceres Roxana
Published: April 2023

En este artículo hacemos un análisis de los avances en el sistema de gestión pública ambiental en las últimas dos décadas, a partir del balance de la agenda de investigación y política ambiental que se delineaba y debatía en la década de 1990. El objetivo es identificar los avances así como las tareas pendientes en la política nacional ambiental de cara a la agenda formulada hace una década. Ello facilitará la tarea de formular un conjunto mínimo de políticas públicas ambientales pendientes. El lector interesado en un balance de investigación actualizado podrá recurrir a Barrantes et al. (2008)4 . Este capítulo está dividido en tres secciones. En la primera se hace una breve descripción de la importancia de los recursos naturales con indicadores macroeconómicos como la composición del producto, exportaciones, empleo y recaudación tributaria. La segunda sección es un balance de los avances y vacíos en la implementación de las diferentes etapas del sistema de gestión pública ambiental, poniendo especial atención a aquellas recomendaciones de política que se elaboraron durante la década pasada, de tal manera de tener un conjunto de avances o logros así como también restricciones u omisiones en la actual política nacional del ambiente. Finalmente, a partir de un balance de los avances y limitaciones en la construcción del sistema de gestión pública ambiental, el capítulo culmina con un conjunto de conclusiones y recomendaciones de política.
Políticas comerciales internacionales y la estructura del comercio exterior peruano
Authors: Ponce Regalado María de Fátima
Published: April 2023

El presente artículo incluye cuatro capítulos. El primero es una introducción, mientras en el segundo se presentan los antecedentes del marco analítico de los acuerdos internacionales y de las estrategias comerciales seguidas en los últimos años en el Perú, resaltando su importancia en la economía, así como destacando sus beneficios y riesgos. En el tercer capítulo se realiza el diagnóstico de la situación actual del comercio externo peruano de bienes y servicios, se presentan los acuerdos y las políticas comerciales implementadas en nuestro país y se discuten los factores que limitan la eficacia de la política comercial. Finalmente, en el último capítulo se formulan las recomendaciones y propuestas de estrategias de política comercial y económica a fin de elevar la productividad y competitividad de la economía.
Economía nacional de mercado : una estrategia nacional de desarrollo para el Perú
Authors: Jiménez Félix
Published: April 2023

Este artículo contiene nuestra propuesta de una estrategia nacional de desarrollo para el Perú, denominada «Economía Nacional de Mercado», cuyo objetivo es centrar, o endogenizar, la fuente de generación de demanda e ingresos al interior del país. Es importante señalar, desde el inicio, que la Economía Nacional de Mercado (ENAM) es una estrategia de desarrollo que difiere tanto del desarrollismo Cepalino como del neoliberalismo.
Julio C. Tello vs. Max Uhle en la emergencia de la arqueología peruana
Authors: Kaulicke Peter
Published: April 2023

Los trabajos de Tello se concentran entre los años de 1913 y 1944; algo más de la mitad de ellos son artículos en periódicos o revistas de divulgación, igualmente de difícil acceso al interesado (Espejo 1948). Asimismo para Te11o vale que gran parte de sus manuscritos se encuentran escondidos, en su caso en un archivo inaccesible
Las ruinas de Moche
Authors: Uhle Max
Published: April 2023

Pocas de las di versas culturas que se desarrollaron en la antigua América poseen una relevancia destacada y ocupan un lugar tan · alto de acuerdo a su grado de desarrollo como la antigua civilización peruana de la zona de Trujillo y Chimbote que destaca por sus vasijas figurativas polícromas. Desde hace ya 40 años, quizás más aún, grandes, hasta interminables series de estas piezas, han llegado a los diferentes museos de Europa sin que hasta ahora se haya logrado emitir un juicio generalmente aceptado acerca de su origen étnico y la posición histórica que le corresponde en el conju'nto de las antiguas' culturas peruanas.
Los poetas y la revolución
Authors: Hildebrandt César
Published: April 2023

Antonio Cisneros fue un hereje cuando publicó Comentarios reales, versión corrosiva, clandestina alegoría de nuestra historia. En ese libro sustantivo y lineal, Cisneros proponía paralelamente un desengaño y un método: su administrada fobia por la historia oficial y el rescate de los verdaderos protagonistas de nuestra épica, es decir los hombres y mujeres marginados de los partes de batalla, el pueblo en su sentido más activo y dialéctico.
Poética y política de la transgresión : Antonio Cisneros
Authors: Bermúdez Gallegos Marta
Published: April 2023

En el Perú no se puede hablar de poesía, a partir de la generación de los '60, sin que surja a la mente la voz irónica y mordaz de la poesía crítica y desmitificadora del Cimeros de la primera época y la del Cimeros actual, cuya poesía denuncia en un tono más introspectivo que cáustico. Sin duda la contribución mayor de Antonio Cimeros a la tradición poética peruana ha sido la de elaborar una poética de la transgresión cultural. Desde la Biblia, los clásicos latinos, la épica y la sátira medieval española hasta Cervantes y Quevedo sirven a la descodificación de la cultura dominante. Tanto el lenguaje de los cronistas coloniales hasta el de Bertolt Brecht y la poesía "beat" norteamericana contribuyen a la creación de una voz poética inconfundible, crítica de todo, incluso hasta de sí misma. Las "crónicas" poéticas de Cisneros construyen sendas vitales propias en las que el/la lector,a se so, lidariza a las buenas o a las malas. El poeta es irreverente y el lector así deberá aceptarlo en toda la ira de su humor acre, desacralizante y desmitificador.
El bien y la explicación : República 465 a ss.
Authors: Ooms Nicole
Published: April 2023

En términos de una teoría de la explicación, el Fedón da, fundamentalmente, dos frutos: en primer lugar, proporciona una reflexión en torno a la distinción entre un explanans, propiamente dicho, y aquello que implementa dicho explanans. 1 En segundo lugar, y es lo que aquí interesa, ofrece un modelo de explicación: la a veces llamada «respuesta ingenua» (todo lo que es bello a nivel sensible lo es a causa de lo Bello en sí). 2 Dicho modelo parece aplicar tres criterios: l. Explanans y explanandum han de ser diferentes sin ser opuestos. 2. Explanans y explallalldum tienen entre sí algún tipo de similitud. 3. Explanans y explana!ldum constituyen un par ordenado
Sócrates joven y anciano : del Parménides al Fedón
Authors: Simpson Peter Phillips
Published: April 2023

El Parménides es el primero de todos los diálogos socráticos de Platón (es decir de aquellos diálogos en los cuales Sócrates aparece). Solo en el Parménides aparece Sócrates como un hombre joven. En todos los demás diálogos parece ser cuando menos un hombre de mediana edad. En el F edón, por el contrario, es un anciano de setenta años y al final del diálogo muere. La República se ubica en algún lugar entre estos diálogos. Tales cuestiones están fuera de discusión. Lo que no lo está es el significado que debe otorgárseles. Para nuestra lectura y comprensión de los diálogos, ¿debemos seguir la cronología de los diálogos conforme a la edad de Sócrates (cronología dramática)? ¿O debemos más bien seguir aquella conforme al momento en el que Platón los escribió (cronología histórica)? El mundo académico, en su mayoría, ha decidido adoptar la última opción. Yo propongo que adoptemos el primero y por varias razones.
¿Por qué la doctrina de la reminiscencia está ausente en los libros centrales de la República?
Authors: Kahn Charles H.
Published: April 2023

Quisiera tratar aquí un problema general, el del status de las doctrinas filosóficas en los diálogos de Platón, aunque refiriéndolo a un caso especial: la ausencia de la doctrina de la reminiscencia en la República
Viaje al fondo del espacio de Un mundo para Julius
Authors: Ferreira César
Published: April 2023

Desde su publicación en 1970, la novela Un mundo para Julius fue elogiada como uno de los retratos más notables de la clase alta peruana y convirtió a su autor, Alfredo Bryce Echenique, en uno de los escritores peruanos contemporáneos más celebrados por un amplio público lector. A treinta años de su aparición, 1 la novela de Bryce no solo es ya una obra clásica de las letras peruanas, sino también un importante documento para estudiar la privilegiada existencia de esta clase social, sus modos de entender la realidad nacional, así como sus relaciones con otros grupos que configuran el escenario social peruano, con sus valores, sus conflictos y sus prejuicios.
Bryce, cronista
Authors: Ferreira César
Published: April 2023

Alfredo Bryce Echenique tiene ya un lugar bien merecido en la literatura hispanoamericana contemporánea con sus novelas y sus cuentos. Pero, paralelamente a su producción ficcional, su labor periodística también ha sido prolífica y, sin duda, no menos interesante. Crónicas personales (Barcelona, Anagrama, 1988) da cuenta de la intensa labor que el autor de Un mundo para Julius ha desarrollado a lo largo de más de veinte años en el periodismo. Los 26 textos que componen el volumen de Crónicas personales son, en realidad, una versión corregida y aumentada de un primer libro, que apareció en 1977 con el título de A vuelo de buen cubero. Con una escritura siempre amena, plena de oralidad, ternura y desenfadado humor, Bryce confiesa, desde un principio, que «sólo puede llegarse a una objetividad total mediante una subjetividad bien intencionada». Y es esa subjetividad la que aprovecha el autor para introducirnos en un mundo rico en anécdotas y peripecias verbales, donde el afán ficcional a ratos parece querer imponerse sobre la realidad que se describe.
Alfredo Bryce : tres historias nostálgicas
Authors: González Vigil Ricardo
Published: April 2023

Luego de dominar el cuento (Huerto cerrado, La felicidad, ja, ja y Magdalena peruana) y la novela (Un mundo para Julíus, Tantas veces Pedro, La vida exagerada de Martín Romaña, El hombre que hablaba de Octavia de Cádiz y La última mudanza de Felipe Carrillo), Alfredo Bryce Echenique nos entrega un notable tríptico de novelas breves, bajo el título de la primera de ellas: Dos señoras conversan (Barcelona, Plaza y Janés, 1990).
... Y lo hizo a su manera : las antimemorias de Alfredo Bryce Echenique
Authors: Márquez Ismael P.
Published: April 2023

La publicación de Permiso para vivir (Antimemorias) (1993) de Alfredo Bryce Echenique (1939), a escasos meses de la aparición de la exitosa traducción al inglés de Un mundo para Julius (1970), es solo el más reciente capítulo en una larga y fructífera carrera que lo ha situado en un lugar preferencial dentro del concierto de escritores hispanoamericanos. A juzgar por el número de ediciones, el público lector ha respondido con entusiasmo inusitado, aun tomando en cuenta que casi simultáneamente aparecían El pez en el agua, las esperadas y controvertidas memorias de Mario Vargas Llosa (1936), y La tentación del fracaso, el diario personal de Julio Ramón Ribeyro (1929). Lo insólito de esta coyuntura editorial es el tono eminentemente confesional de las tres obras, elemento que sin duda ha contribuido en gran medida al interés sin precedente que han generado.
Del amor y otras (divertidas) tragedias
Authors: Serna Mercedes
Published: April 2023

Puede que deje de ser Un mundo para Julíus «la novela cumbre» del escritor peruano Alfredo Bryce Echenique (1939), ahora que acaba de publicarse No me esperen en abril, obra que guarda estrecha relación con su producción anterior. Bryce empezó No me esperen en abril en julio de 1976, aunque la dejó para escribir Tantas veces Pedro.
Decadencia social y forma novelesca en dos textos de Alfredo Bryce Echenique
Authors: Castro Urioste José
Published: April 2023

El vasto, complejo y conflictivo proceso de la literatura peruana está constituido no solo por un sistema literario, sino por una pluralidad de ellos que se desarrolla en constante y permanente interacción. Dentro de estos sistemas se encuentra aquel vinculado al ejercicio de una literatura escrita -en castellano, obviamente-, a un lector urbano, al mundo de la industria de la cultura. En contraste, se produce una literatura oral desarrollada en lenguas nativas como también en castellano, que implica el uso de estrategias narrativas que difieren de la literatura escrita, tales como la participación y presencia del productor y receptor del discurso en el mismo espacio, y la construcción de un imaginario que se enuncia y representa una problemática no «occidental» (sea india, sea negra, por ejemplo).