bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of Microbiocenoses of Various Biotopes in Women as Potential Miscarriage Risk Factor
Authors: Goncharov A. E. , Rischuk S. V. , Aslanov B. I. , Lebedeva E. A. , Azarov D. V. , Mokhov A. S. , Artemova Yu. A. , Tabolkina M. V. , Meltser A. A. , Osmirko T. V. , Tushina A. V.
Published: November 2021

Relevance. Miscarriage is one of the most common obstetric pathologies that determine the spontaneous death of the fetus. The role of changes in the microbiome of various biotopes is considered as a risk factor of this disease.

Aim of the research is to assess the microbiocenoses structure of the reproductive system and the intestine associated with the development of spontaneous miscarriages in early pregnancy.

Materials and methods. A case-control study was conducted and organized. The group of «cases» included 23 women with spontaneous miscarriage at 5–14 weeks of pregnancy and the control group included 23 women with normal pregnancies Based on the data of metagenomic sequencing of V3–V4 regions of the 16S rRNA gene, a comparative assessment of the structure of the vaginal and intestinal microbiome in these groups was carried out.

Results. As a result of the study, a number of taxonomic groups of microorganisms in the vagina and intestines associated with miscarriage. It was found that the decrease in the proportion of Lactobacillus spp. in the structure of the vaginal microbiome, less than 90% of the total number of identified taxa is associated with this pathology (OR = 5.28 (95% CI = 1.2-23.2)). The gut microbiocenoses of women with spontaneous miscarriage are characterized by less taxonomic diversity than the gut microbiome of women with advanced pregnancy. At the same time, some representatives of the intestinal microbiome (Akkermansia sp., Faecalibacterium sp., Bifidobacterium sp., Methanobrevibacter sp., Lactococcus sp.) predominate in women with a normal pregnancy.

Conclusion. The study demonstrated a significant role of changes in microbiocinosis of the reproductive tract and intestines in miscarriage. There is a potentially protective function of lactobacilli. The obtained data substantiates the need for active use of molecular genetic methods focused on the assessing the structure of the vaginal and intestinal microbiota in assessing the risks of reproductive failures.
xperimental Evaluation of the Possibility of using the LAL test to Determine Bacterial Endotoxins in Vaccines for Rabies Prophylaxis
Authors: Muhacheva A. V. , Barkhaleva O. A. , Shapovalova O. V. , Neugodova N. P. , Butirskiy A. Yu. , Movsesyants A. A. , Volkova R. A. , Sarkisyan K. A.
Published: November 2021

Relevance. The presence of pyrogenic impurities in finished dosage forms of concentrated cultural anti-rabies vaccines produced in the Russian Federation is determined using pyrogenicity tests on rabbits (in vivo). In accordance with the decision of the Board of the Eurasian Economic Commission dated September 7, 2018 N 151 «On the approval of guidelines for drawing up a regulatory document on the quality of a medicinal product», one of the requirements for parenteral drugs is the determination of bacterial endotoxins. This document indicates that the regulatory documentation should include a test and an admissibility criterion for bacterial endotoxins (BE) using the horseshoe crab amoebocyte lysate technique.

Aims. Experimental evaluation of the possibility of using the LAL-test to determine bacterial endotoxins in national vaccines for the prevention of rabies.

Materials and methods. The research of the drug «Cultural antirabies vaccine concentrated inactivated purified» of national production was carried out in accordance with the National Pharmacopoeia of the Russian Federation, General Pharmacopoeia Monograph OFS.1.2.4.0006.15 in three modifications: gel-clot test: methods A, B; turbidimetric kinetic test: method C; chromogenic kinetic test: method D.

Results. Was investigated 6 series of the national vaccines for the prevention of rabies from two national manufacturers (using three pharmacopoeial methods). LAL reagent produced by two companies (Charles River Endosafe® and Lonza). In order to confirm the reproducibility of the method, the gel-clot test was carried out at different time intervals by one or two operators. During the research was determined the possibility of using photometric methods (method C and D).

Conclusions. The research proved the possibility of determining bacterial endotoxins by methods: gel-clot test (method A), turbidimetric kinetic test (method C) and chromogenic kinetic test (method D). Method B is recommended for quantitative analysis of vaccine without instrumental methods. During the research all national vaccines for the prevention of rabies was free from bacterial endotoxins (no more 25 EU/ml).
Immunobiological Properties of Biofilms of Bacteria of the Genus Bordetella
Authors: Zaitsev E. M. , Bazhanova I. G. , Britsina M. V. , Ozeretskovskaya M. N.
Published: November 2021

Relevance. Whooping cough remains a pressing public health problem worldwide, including in countries with high vaccination rates. One of the probable causes of the ongoing epidemic process of pertussis infection is B. pertussis biofilms, which differ from plankton cultures by an altered gene expression spectrum and are highly resistant to environmental conditions, antibiotics, and immune factors.

Aims. Analysis of literature data on the genetic and molecular - cellular mechanisms of biofilm formation by bacteria of the genus Bordetella, as well as approaches to the search for means aimed at suppressing the growth of biofilms and the destruction of formed biofilms in the macroorganism.

Conclusions. Biofilm formation by microbes of the genus Bordetella is a complex multistage process regulated by genetic signaling systems: the Bvg AS system and the 2-nucleotide (p) ppGrp system, as well as other regulatory proteins and the polysaccharide complex. The matrix of B. pertussis biofilms consists of extracellular DNA, proteins, and a polysaccharide polymer that play an important role in the formation of biofilms in the respiratory tract and on abiotic surfaces. The genetic and molecular-cellular processes of biofilm formation and maintenance, as well as the various components of the biofilm matrix, can serve as targets for new antimicrobial drugs and more effective pertussis vaccines that will better control the entire pertussis infection cycle, including colonization, persistence, and transmission of the causative agent. One of the approaches to the development of new-generation cell-free pertussis vaccines is the identification of new biofilm-associated antigens that can induce effective cellular and humoral responses. The search for drugs that can destroy biofilms, including substances that affect the matrix and facilitate the access of antibacterial drugs to microbial cells, is promising.
Analysis and Outlook for the Development of Measles Epidemic Situation during the COVID-19 Pandemic
Authors: Semenenko T. A. , Nozdracheva A. V.
Published: November 2021

Relevance. The success of the global community in the fight against measles through vaccination at the beginning of the twentyfirst century allowed WHO to declare the goal of eliminating this infection by 2010. However, ten years later, the problem of the growing incidence of measles has become relevant again for all countries of the world. The pandemic of the new coronavirus infection (COVID-19) has affected all spheres of human life and has exacerbated the situation in the fight against other infections, including those managed with the help of specific prophylaxis. Since the measles contagiosity index and mortality rate are significantly higher than similar characteristics of COVID-19, the risk of increasing the incidence of this infection in the coming years is difficult to overestimate.

Aim of the study: to assess the epidemic situation of measles in the context of the COVID-19 pandemic, as well as the prospects for its development; to propose preventive measures.

Materials and methods. The article analyzes the statistical materials available on the official websites of the WHO (WHO). https://www.who.int/data/), the CDC US (https://www. cdc.gov) and the Federal Service of Rospotrebnadzor (https://www.rospotrebnadzor.ru/) on vaccination coverage and measles incidence in 13 countries in the WHO European Region and the United States. The epidemic situation on measles, as well as the level of population coverage with vaccination against its pathogen in the Russian Federation, were assessed according to the Federal State Statistical Observation forms 2010 – 2020: Form 2 «Information on infectious and parasitic diseases» and Form 6 «Information on the populations of children and adults vaccinated against infectious diseases».

Results. It has been established that the increase in the measles incidence occurred in 2017–2019 worldwide, including European countries with a population coverage of two vaccine doses at the 97% level between 2010 and 2019. The prevalence of measles cases in children under the age of 10 is shown, as well as the wide range (from 56.9% to 10.9%) in the proportion of vaccinated persons among them. The results obtained indicate the existence of problems in the organization of modern vaccine prevention. The introduction of widespread restrictive and quarantine measures against the COVID-19 pandemic, on the one hand, has reduced the incidence of measles and, on the other hand, has exacerbated the difficulties in implementing measles prevention. Thus, the results indicate a possible increase in measles incidence in the population after the end of the COVID-19 pandemic.

Conclusion. It is necessary to immediately develop an action plan to catch up on the coverage and increase the rate of routine vaccination, to improve the statistical record of persons subject to the introduction of the vaccine and vaccinated, as well as to overcome anti-vaccination attitude among the population.
Assessment of Seroconversion to SARS-CoV-2 in Health Care Unitunit Personnel
Authors: Blokh A. I. , Panyushkina I. I. , Pakhtusova P. O. , Sergeeva I. V. , Levahina L. I. , Burashnikova I. P. , Anpilova N. G. , Penyevskaya N. A. , Pasechnik O. A. , Rudakov N. V.
Published: November 2021

Relevance. The novel coronavirus pandemic is a major burden on public health and healthcare professionals. The study of the prevalence of antibodies among medical workers provides an understanding of the potential risk of transmission of the infectious agent, the level of herd immunity, the introduction of specific immunization and risk stratification in various areas of professional activities.

The purpose of this study was to assess the level of specific antibodies to SARS-CoV-2 in the personnel of the medical and sanitary unit, providing the population with outpatient and inpatient medical care.

Materials and methods. A study to assess seroprevalence to the SARS-CoV-2 virus was carried out in the Omsk region from September 2020 to December 2020. The study included 2 groups of employees of continuously operating organizations – the main group – employees of the medical and sanitary unit of the city of Omsk (n = 631), the control group consisted of employees of two industrial enterprises in the city of Omsk (n = 1696). The level of class G immunoglobulins to the SARS-CoV-2 virus was determined by enzyme-linked immunosorbent assay.

Results. Among medical workers, the proportion of people with a positive reaction to IgG was 73.1% (n = 461; 95% CI 69.5–76.4%). In the control group, the proportion of those who were seropositive was 3.9 times less than that – 18.6% (n = 315; 95% CI 16.8–20.5). Significant differences in seroprevalence in men and women were revealed in medical workers (χ2 = 4.164; p = 0.0413). The highest proportion of seroconversion was found in nursing staff – 85,4% (95% CI 71.6 – 93.1), in doctors – 63.3% (95% CI 55.0–70.9). The highest rate of seroprevalence was found among hospital medical workers – 81.9%, the lowest among employees of the administrative and economic service – 51,8%.

Conclusions. The level of specific antibodies to SARS-CoV-2 among medical workers significantly exceeded that of other professional groups, and there was a high proportion of seroconversion among junior medical personnel and in-patient medical unit workers.
Modeling of the Potential Effect of Revaccination against Whooping Cough in Children Aged 6–7 and 14 years within the Framework of the National of preventive vaccinations
Authors: Briko N. I. , Mindlina A. Ya. , Mikheeva I. V. , Popovich L. D. , Lomonosova A. V.
Published: November 2021

Relevance. Currently, the national calendar of preventive vaccinations does not provide for revaccination against whooping cough in children over the age of 18 months. At the same time, the epidemiological and economic feasibility of revaccination against whooping cough in children aged 6–7 years, as well as adolescents, has been demonstrated in world practice. Aim. Based on a mathematical model, develop a forecast of pertussis morbidity dynamics and assess the potential socio-economic damage under the current and expanded vaccine prophylaxis algorithms.

Methods. Mathematical modeling of the potential effect of revaccination against whooping cough in children aged 6–7 years (scenario 1) and at 6–7 years and 14 years (scenario 2) was carried out within the framework of the national calendar of preventive vaccinations. A simulation dynamic mathematical model is constructed that allows predicting the development of the epidemiological process of whooping cough on the basis of the dynamics of the main indicators of its prevalence in the population that developed in previous years. The model took into account dynamic changes in the preventive effectiveness of vaccinations and the potential level of underestimation of morbidity. The obtained arrays of indicators served as the basis for extrapolating trends in morbidity and mortality until 2034.The calculation of epidemiological benefits was carried out in the metrics of prevented loss of years of life under the two scenarios under consideration in comparison with the current vaccination algorithm. The calculation of the economic effect was carried out on the basis of the obtained indicators of epidemiological benefits in the metrics of the monetary equivalent of the average cost of a year of life, taking into account the projected inflation coefficients until 2034.

Results. The projected decrease in the number of years of life lived in a state of illness, in comparison with the current situation, will total 44.5 thousand years for the period 2019–2034 under scenario 1 and 66.7 thousand years under scenario 2. The socio-economic damage from prevented cases of the disease, expressed in the monetary equivalent of the average cost of living, will decrease by 28.6% (scenario 1) or 42.0% (scenario 2).

Conclusions. A comparison of the received public benefits with the costs of vaccination shows that the expansion of the NCPP with additional revaccinations against whooping cough (at 6–7 years or at 6–7 and at 14 years) is advisable both in epidemiological and economic aspects.
Analysis of External Risks of Cholera Importation to the Territory of Primorsky Krai by Different Types of Transport
Authors: Khunkheeva Zh. Yu. , Mironova L. V. , Seleznev V. A. , Chebotar M. A. , Kovalenko A. I. , Kuznetsova I. V. , Balakhonov S. V.
Published: November 2021

Relevance. The risk of developing complications of an epidemiological nature for especially dangerous infections is determined by the possibility of importing an infection from disadvantaged countries, which depends on many factors, including the migration activity.

Aim. To analyze the external risks of cholera importation into Primorsky Krai by various modes of transport.

Materials and methods. Data of the Federal Service for Surveillance on Consumer Rights Protection and Far Eastern territorial department Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing by railway transport was used. The analysis of the incidence of cholera in the world was carried out according to the WHO, the Reference Center for Monitoring Cholera in the Russian Federation, the Internet resource ProMED-mail.

Results and discussion. During the analyzed period (2015–2018), 311,435 vehicles (automobile transport – 87.4%, sea transport – 7.7%, air transport – 4.3%, railway transport – 0.6%) and more than 5 million people arrived in Primorsky Krai from abroad. Analysis of passenger flows by all modes of transport showed that Asian destinations dominate.

Conclusion. Evaluation of the epidemiological situation of cholera in the Southeast Asian countries does not rule out the risk of cholera importation into Primorsky Krai, given the high intensity of migratory activity. No conflict of interest to declare.
Evaluation of Epidemiologic Peculiarities of HIV-Infection and Genotype Distribution of Hepatitis C Virus among People Living with HIV in Constituent Entities of the Far Eastern Federal District
Authors: Bazykina E. A. , Turkutukov V. B. , Trotsenko O. E. , Kotova V. O. , Balakhontseva L. A.
Published: November 2021

Relevance. Monitoring the genotypic diversity of the hepatitis C virus as well as its prevalence in the population, including in certain population groups, is an important public health task.

Aim. To analyze main epidemiological indices (incidence and prevalence) among people living with HIV and evaluate abundance of chronic hepatitis C among them, reveal molecular-genetic distribution of hepatitis C virus (HCV) isolated from HIV-positive people living in the Far Eastern Federal district (FEFD) of the Russian Federation.

Materials and methods: a retrospective epidemiological analysis including estimation of HIV-infection incidence and prevalence as well as percent of HIV-positive people suffering from chronic viral hepatitis C was conducted for nine constituent entities of the FEFD. Molecular genetic analysis included evaluation of 120 samples of serum positive for HCV RNA that was obtained from people diagnosed with HIV-infection. A type-specific commercial PCR test-kit as well as partial sequencing by Sanger of HCV NS5B gene (241 bp and 350 bp) were utilized in order to specify HCV genotypes.

Results and discussion: in total 26.26% of people living with HIV were registered for regular medical examination due to chronic hepatitis C in the FEFD in year 2019. Their percentage has grown over a 5-year period. Dominant HCV subtype among surveyed HIV-positive people was subtype 3a followed by HCV subtype 1b. HCV genotype 2 and subtype 1a were detected less frequently and were identified as minor genotypes. Genotype distribution among people aged under 35 years was more significant in comparison with older citizens. Some regional particularities were discovered. For example, HCV genotype 2 was registered more frequently in the Khabarovsk krai compared to mean estimated value of the sampling collection. Subtype 1b was dominant in Republic Sakha (Yakutia).

Conclusion: an increase in percent of HIVinfected people suffering from chronic hepatitis C has been noted during a 5-year period. Should be noted that the value varies in different constituent entities ofthe FEFD. Molecular-genetic analysis showed general prevalence of HCV 3a subtype while 1b HCV subtype is dominant in the Russian Federation in patients suffering from HCV-monoinfection as well as in those infected with HIV and HCV.
Peculiarities of the Spread of HIV infection among Urban and Rural Residents of the Tyumen Region
Authors: Mel`nikova E. N. , Marchenko A. N.
Published: November 2021

Relevance. The geographical spread of HIV infection among the population of various administrative territories is very heterogeneous. The Tyumen region, due to its vast territory and the significant remoteness of some areas from the regional center, is of particular interest in the framework of considering the territorial features of the spread of HIV.

Aims. To consider peculiarities of the spread of hiv infection among urban and rural residents of the Tyumen region in 1993–2019.

Materials & Methods. Statistical data of the «Center for the Prevention and Control of AIDS» in the period from 1993 to 2019, annual form No. 61 «Information on the contingents of HIV patients» for 2006–2019, materials of the state report «On the sanitary and epidemiological situation in the Tyumen region» for 2013–2019. Methods of epidemiological observation were used in the work: analytical and descriptive-evaluative with the use of methods of retrospective and operational analysis and statistical methods.

Results and Discussions. A specific feature of the spread of HIV infection among urban and rural residents is the tendency to exceed the regional incidence rate in a number of territories. Analysis of epidemiological data for the period under review showed that all territories of the region are involved in the epidemiological process of HIV infection, and in a number of territories the prevalence rate exceeds the average Russian level. HIV prevalence as of December 31, 2019 was 728.2 per 100 thousand people in Russia. In 17 administrative territories of the Tyumen region the infection rate is higher than the national average level and is per 100 thousand population in the city of Tobolsk – 1903.3, in the districts of Uvat – 1486.2, Tobolsk – 1440.5, Nizhnetavda – 1354.9, Tyumen – 1344.1, Yalutorovsk – 1327.6), in the city. Tyumen – 1249.3, in the districts: Vagay – 1195.2, Zavodoukovsky – 1119.2, in Ishim – 951.8, in the districts: Yarkovsky – 889.6, Vikulovsky – 881.3, Yurginsky – 846.9, Ishimsky district – 842.1, Aromashevsky – 851.6, Isetovsky – 754.4, Uporovsky district – 734.7.

Conclusions. The HIV epidemic in the Tyumen region is determined by its economic and geographic location and by the presence of exceptional epidemiologically significant prerequisites for the intensive spread of HIV, in particular, by the routes through which large quantities of drugs are illegally transported (drug trafficking from the northeast).
INSTILLING VALUE-SIGNIFICANCE IN LAND OWNERSHIP IN THE NORTHERN CAPE PROVINCE
Authors: Parker Gail Denise , Costa King
Published: November 2021

The concept of value-significance in landownership has been viewed from only one dimension – the economic dimension. This study focused on the intrinsic dimension, sometimes theoretically called “place attachment” to determine how this component could be infused in land reform support and maintenance programmes directed towards beneficiaries of the land redistribution programme in the Northern Cape province of South Africa. The current state of post-land redistribution programme is characterized with a plethora of problems that lead to discouraged beneficiaries, unproductive land use and ultimate land degradation. This study sought to answer the question, “How to instill value-significance in land ownership to beneficiaries of the land redistribution programme in the Northern Cape Province”. An interpretivist phenomenological approach was selected as method of inquiry, purposively selecting ten study participants from different cohorts of the land redistribution programme between the period 1994 to 2018. Semi-structured interviews were conducted to obtain in-depth insights, to describe the lived experiences of participants. Aligned with ethical standards, interviews were conducted and recorded on an audio recording device, with the permission of participants. Recorded data was transcribed and analyzed using both thematic analysis benchmarked to the COSTA QDA Technique and the webQDA software. Findings of the study culminated into thematic expressions, namely: land redistribution programme needs to be underpinned by a structured maintenance programme; lives of beneficiaries are transformed; beneficiaries aspire full ownership of the land for productive use. The study concluded in a rigorous synthesis of these thematic expressions and culminated in development of the INSTIL Framework for instilling value-significance in land ownership. It is recommended that the framework for instilling value-significance in land ownership be implemented to enhance the success of the land redistribution programme in the Northern Cape province.Key words: Identity, Instil, Land ownership, Place attachment, Value-significance
THE CHALLENGE OF SUSTAINABLE LAND-BASED LOCAL ECONOMIC DEVELOPMENT IN POOR COMMUNITIES OF SOUTH AFRICA: THE CASE OF GROBLERSHOOP, NORTHERN CAPE
Authors: Parker Gail Denise
Published: November 2021

Since the advent of South Africa’s democracy, there have been many pressing questions; one of which has been: ‘to what extent has the newly found political and civil freedoms, which is guaranteed for all South Africans, translated into an a more economically-viable life?’ This research investigates whether local economic development (LED) interventions necessarily improve the livelihoods of poor communities. More specifically, the goal of this thesis is to explore some of the reasons why land-based economic development interventions often struggle to meet their main objective of improving the livelihoods of local poor people. It is hoped that the findings of this research will assist policymakers and local economic development planners in making more informed decisions.Using a qualitative research methodology, a three- pronged approach is adopted to address the key goal of this thesis. First, a review of the literature on LED was conducted: a comparative study into its origins in wealthy, developed countries; and the experiences on the successes and failures of LED as a developmental tool. Secondly, a review was made of the experiences of the application on LED approaches in a South African context, with special reference to the policy and support of LED strategy. Thirdly, a case study of Groblershoop, which is in the Northern Cape, is presented. It focuses on LED that is based on land, and the role that it plays in the livelihood approaches of poor people. In conclusion, it is posited that while the potential of land-based LED is not disputed, the implementation of such strategies are often inconsistent with the overall objective of poverty alleviation and economic development. For this reason, local municipalities will not be able to do this without clear policy guidance; institutional capacity-building; inter-sectoral collaboration of political ‘champions’ to drive the process; and real empowerment of the beneficiaries whom the projects are supposed to assist.
DRIVERS FOR LOCAL ECONOMIC DEVELOPMENT IN SOUTH AFRICAN MUNICIPALITIES
Authors: Parker Gail Denise , Costa King
Published: November 2021

Local economic development (LED) within municipalities in South Africa has been viewed as a failing project by many commentators, practitioners and scholars. One of the areas attributed as a causal factor for distrust on efforts related to local economic development is lack of clarity on foundational dynamics and drivers of LED. This study used interpretivist approaches to analyze key theoretical frameworks that provide explanations for challenges related to articulation of drivers for LED. As a theoretical paper authors established rigor through mapping theories to building blocks of a theoretical argument being the what, when, how and why. The central argument of this paper is that while the potential of LED strategies is not disputed and the economic value of land is , the implementation of such strategies does not assist in achieving the intended objectives of poverty alleviation and economic development. The study concluded that while local municipalities are mandated by the Constitution to “promote social and economic development”, they will not be able to do this without clear policy guidance; institutional capacity-building; inter-sectoral collaboration; political ‘champions’ to drive the process; and real empowerment of the beneficiaries whom the projects is supposed to assist.Key Words : Local economic development. Theoretical framework, Commonage, Business development, Black economic empowerment,
Association between intestinal bacterial carriage, biomarkers of environmental enteric dysfunction and stunting in rural Malawian children
Authors: Chaima David , Hart John D , Pickering Harry , Burr Sarah , Maleta Kenneth , Kalua Khumbo , Bailey Robin , Holland Martin
Published: November 2021

BackgroundGut bacteria Bifidobacterium longum, Faecalibacterium prausnitzii, Dorea formicigenerans and Akkermansia muciniphila have been implicated in mediation of growth. We investigate the prevalence of these four species, levels of fecal biomarkers of environmental enteric dysfunction (EED) and association with stunting in rural Malawian children. Methods DNA and protein were extracted from fecal samples of 613 children (aged 1-59 months) at a baseline cross-sectional survey in the Mangochi district of Malawi conducted within the framework of the MORDOR (Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance) trial. Intestinal carriage of bacteria was measured by PCR. Neopterin, myeloperoxidase and alpha-1 antitrypsin, biomarkers of EED, were measured by ELISA. Height-for-age Z (HAZ) score <-2 defined stunting. Tests of proportions and regression models were used to explore the relationship between bacterial carriage, EED and stunting.Results B. longum carriage in younger children was associated with elevated EED biomarkers. Two thirds of children had elevated NEO, 33% elevated MPO and 16% elevated AAT. Stunting was found in 38% of the children. No significant associations were found between EED biomarkers or intestinal bacteria carriage and stunting.
The effects of personality traits, organizational identification and trust in the manager at hotel organizations
Authors: İNANIR Ali
Published: November 2021

The aim of the research is to determine the effects of personality traits, organizational identification and trust in the manager at hotel organizations. This study has been carried out in January-June 2019 with employees in five-star hotels located in Antalya, one of the most common holiday destinations in Turkey. In this study, a quantitative research has been conducted and survey technique has been used. 375 questionnaires were analyzed. Research analyses have been performed with the help of SPSS package program and AMOS package program. Frequency analysis, factor analysis and structural equation modelling have been utilized on the study. As a result, openness to experience, conscientiousness and extraversion personality traits have a significant effect on organizational identification and openness to experience, conscientiousness and agreeableness have a significant effect on trust in the managers. In this context, it has been determined that the openness to experience and conscientiousness have a significant effect on organizational identification and trust in the managers. As well as organizational identification has a significant effect on trust in the manager. This research serves as a guide for hotel managers about employees. In this context, the fact that hotel managers prefer employees who are openness to experience and conscientiousness personality traits can benefit their organizations in the long term.
PENGARUH LAJU ALIR ABSORBEN DAN WAKTU KONTAK K2CO3 TERHADAP PENYERAPAN CO2 YANG TERKANDUNG DALAM GAS ALAM
Authors: Fatimura Muhrinsyah , Masriatini Rully , Fitriyanti Reno
Published: November 2021

Gas CO2 atau gas asam (sour gas) merupakan salah satu kandungan dari gas alam yang sifatnya sebagai kontaminan. Adanya kandungan gas CO2 yang tinggi didalam gas alam perlu dilakukan treatment khusus dalam menghilangan kandungan gas asam (sour gas) tersebut dari gas alam dimana proses penghilangan gas asam dari gas alam disebut proses Sweetening. Proses Absorspi gas CO2 merupakan metode yang sering dilakukan. Penelitian ini bertujuan  mengetahui pengaruh laju alir absorben dan waktu kontak terhadap konsentrasi CO2 yang di serap. Metode yang dilakukan dalam penelitian ini yaitu dengan perancangan alat yang bisa menunujukan proses absorpsi CO2. Variabel penelitian yang digunakan memvariasikan  laju alir absorben 4,95 ml/s, 7,26 ml/s, 10,75 ml/s serta waktu kontak 2,4,6,8 menit dengan menggunakan absorben K2CO3 dan   Gas alam yang digunakan compress Natural Gas CNG.  Dari hasil penelitan laju alir Absorbenyang paling baik didapat pada  10,75 ml/s dengan penyerapan  CO2 sebesar  69,45 %. Waktu kontak  pada setiap waktu   tidak berpengaruh banyak  terhadap konsentarsi CO2 yang terserap .  Kata kunci: absorben, Sour gas, gas alam, laju alir  AbstractCO2 gas or acid gas (sour gas) is one of the contents of natural gas which is a contaminant. The presence of high CO2 gas content in natural gas requires special treatment to remove the sour gas content from natural gas where the process of removing acid gas from natural gas is called the Sweetening process. The CO2 gas absorption process is a method that is often used. This study aims to determine the effect of absorbent flow rate and contact time on the absorbed CO2 concentration. The method used in this research is to design a tool that can show the CO2 absorption process. The research variables used varied the absorbent flow rate of 4.95 ml/s, 7.26 ml/s, 10.75 ml/s and a contact time of 2,4,6,8 minutes using K2CO3 absorbent and natural gas used compressed Natural CNG gas. From the research results, the best absorbent flow rate was obtained at 10.75 ml/s with CO2 absorption of 69.45%. Contact time at any time did not have much effect on the concentration of CO2 absorbed. Keywords: absorbent, sour gas, natural gas, flow rate
MODERASI BERAGAMA BERBASIS TRADISI PESANTREN PADA MA’HAD ALY AS’ADIYAH SENGKANG WAJO SULAWESI SELATAN
Authors: Saddam  , Andi EKi
Published: November 2021

Radicalism religion has entered into various sectors of life, including in the realm of education. For this reason, Pesantren as the center of Islamic Education must take a role in the mainstreaming of ideas and moderate attitudes in religion that is in accordance with the noble values of Islam that is peace. In this paper, religious moderation in Ma’had Aly As’adiyah Sengkang will be explored. This paper uses field research which is included in the type of qualitative research using descriptive methods.In this research, it is found that the values of religious moderation in Ma’had Aly As’adiyah; Tawassuth tawazun, I’tidal (fair), tasamuh (tolerance), musawah, Syura, ishlah, aulawiyah, tatawwur wa ibtikar (dynamic and innovative), tahaddur (civilized), wathaniyah wa muwathanah, qudwatiyah. The inculcation of Religious moderation values in Ma’had Aly As’adiyah is carried out by several methods, namely formal classes, halaqah or mappesantreng methods.
RELIGIUSITAS PEREMPUAN MILENIAL BERCADAR DI TENGAH FENOMENA RADIKALISME-TERORISME
Authors: Athik Hidayatul Ummah
Published: November 2021

The appearance of veiled women in terrorist groups and acts of terrorism creates a negative stigma on other groups of veiled women. The trend of millennial women who are involved in acts of terror or suicide bombings and how to dress is in the pros and cons. The veil is still debated in the public. However, there are still many young women who wear the veil. This study aims to find and explain the motives, experiences and meanings of religiosity for veiled millennial women in the midst of the radicalism-terrorism phenomenon. This research method uses a phenomenological approach. The methods of data collection are interviews, observation and literature study. The subjects of this study were veiled women who were represented by a purposive sampling technique, namely based on certain criteria including: younger millennial (22-29 years old), they has used or is currently using the veil, they has read or heard studies about radicalism-terrorism, and they have negative stigma related to the use of the veil. The informants of this study found 5 people in the city of Mataram. Data obtained in the field by qualitative analysis and compared with several appropriate previous studies. The results show that the meaning of religiosity for millennial women with veils explains three dimensions, namely the intellectual dimension (religious knowledge), the experiential dimension (religious feeling), and the consequence dimension (religious effect). Meanwhile, veiled motivation comes from internal and external factors. The motivation can strengthen and change the decision to veil in the midst of the phenomenon of radicalism and terrorism. So there is no ideological dimension to the veiled decision.
Pemberdayaan Diri: Kompetensi Berbahasa Inggris sebagai Modal Simbolik
Authors: Wiandari Fadhillah , Meutia Cut Intan
Published: November 2021

Pengukuran terhadap kapabilitas mahasiswa dan alumni dari program studi Tadris Bahasa Inggris (TBI) perlu dimonitoring dan evaluasi secara berkala. Maka tujuan penelitian ini adalah untuk mengeksplorasi kompetensi penggunaan bahasa Inggris oleh mahasiswa dan alumni program studi TBI sebagai modal simbolik untuk mengembangkan diri. Jenis penelitian ini merupakan penelitian kualitatif dengan format studi kasus. Instrumen yang digunakan adalah wawancara dan Focus Group Discussion. Hasil penelitian menunjukan bahwa modal simbolik yang dimiliki mahasiswa masih sangat lemah. Mahasiswa tidak memiliki modal yang sesuai dengan program studi untuk mengembangkan dan memberdayakan diri mereka sendiri. Dilihat dari sisi ekonomi, pada mahasiswa dan alumni tidak ditemukan mahasiswa yang memiliki kekuatan modal kapital. Dan dari segi modal budaya, mahasiswa TBI atau alumni belum memiliki karakter yang signifikan baik berupa cara bergaul ataupun cara pembawaaan diri yang menjelaskan bahwa mereka adalah mahasiswa atau alumni program studi ini. Hal ini mengakibatkan sulitnya alumni untuk memberdayakan diri
Jurnal SISTEM INFORMASI E-LEARNING KURSUS KOMPUTER PADA LKP OBY KOMPUTER TEMBILAHAN
Authors: Edward  , Samsudin
Published: November 2021

Dalam melaksanakan kegiatan belajar mengajar pada lembaga kursus, seorang instruktur pasti pernah dihadapkan pada berbagai permasalahan baik dari faktor internal maupun eksternal. Salah satu contoh nyata permasalahan dari faktor eksternal yang terjadi pada saat ini yaitu pandemi Virus Corona (COVID-19). Penyakit berbahaya yang penularannya terbilang sangat cepat membuat hampir seluruh negara memberlakukan Lockdown demi menangani penularan virus tersebut. Dengan diberlakukannya status Lockdown tersebut, ternyata berdampak bagi pendidikan khususnya kegiatan belajar mengajar. Menyikapi hal tersebut maka pemerintah menghimbau agar proses kegiatan belajar mengajar dilakukan dirumah dengan menggunakan media internet.Demi tetap berlangsungnya pembelajaran ditengah pandemi yang terjadi saat ini, peneliti yang sekaligus seorang instruktur kursus komputer pada Lembaga Kursus dan Pelatihan (LKP) Oby Komputer telah merancang sebuah website E-learning. Melalui sistem informasi Website E-Learning kursus komputer pada LKP OBY Komputer ini bertujuan untuk menganalisa, merancang dan mengimplementasikan sistem pembelajaran kursus komputer jarak jauh. Penggunaan metode Waterfall sebagai  metode pengembangan sistem berfungsi sebagai sebuah mekanisme untuk mengidentifikasikan perangkat lunak, serta UML (Unified Modeling Language) sebagai pemodelan, dan menggunakan metode PIECES untuk memudahkan peneliti dalam membangun sistem.Sistem Informasi Website E-Learning kursus komputer pada LKP OBY Komputer Tembilahan dapat mempermudah para peserta didik/siswa melalukan proses pembelajaran dengan menggunakan metode daring.
SISTEM INFORMASI GEOGRAFIS BERBASIS WEB PERSEBARAN FASILITAS PELAYANAN KESEHATAN DI KOTA TEMBILAHAN
Authors: Tarmizi Dimar , Ridha Muh. Rasyid
Published: November 2021

Kota Tembilahan merupakan pusat dari Kabupaten Indragiri Hilir yang terletak di Provinsi Riau, Indonesia. Di kota, fasilitas pelayanan kesehatan mempunyai peranan penting dalam penyelenggaraan upaya pelayanan kesehatan perorangan, baik preventif, promotif, kuratif, maupun rehabilitatif yang dilakukan oleh pemerintah pusat, pemerintah daerah dan/atau masyarakat. Salah satu unsur utama Manajemen Kesehatan adalah informasi kesehatan berupa hasil pengumpulan dan pengolahan data yang merupakan masukan bagi pengambil keputusan di bidang kesehatan. Penelitian ini berupa aplikasi Sistem Informasi Geografis (SIG) berbasis web persebaran fasilitas pelayanan kesehatan berbasis web dengan wilayah penelitian di Kota Tembilahan. Penyampaian dan tampilan sistem informasi geografis dapat lebih informatif serta mempresentasikan kondisi sebenarnya. Sistem dikembangakan menggunakan bahasa pemrograman PHP dengan framework CodeIgniter. Tampilan sistem menggunakan framework Bootstrap dan template SB Admin 2. Peta yang digunakan pada aplikasi adalah peta digital yang disediakan oleh OpenStreetMap dan ESRI.
APLIKASI ePOSYANDU KESEHATAN IBU DAN ANAK DI KECAMATAN KEMPAS JAYA
Authors: Prasetyo Dwi Yuli , Yunita Fitri , Setiawan Ricky
Published: November 2021

Posyandu Srikandi II merupakan suatu unit layanan kesehatan yang bertugas untuk melakukan pelayanan kesehatan ibu dan anak (KIA) di wilayah RT 05 d RW 09 Kelurahan Kempas Jaya, Kecamatan Kempas. Saat ini, proses manajemen data di Posyandu Srikandi II masih dilakukan secara manual dengan cara mencatatkan data kedalam buku format register. Cara tersebut dinilai tidak efisien karena menyebabkan kesulitan dalam proses manajemen data Posyandu Srikandi  II. Untuk mengatasi permasalahan tersebut, maka penulis bermaksud mengembangkan suatu sistem informasi posyandu berbasis web. Pengumpulan data dilakukan dengan cara observasi dan wawancara. Metode pengembangan sistem yang digunakan adalah Unified Modelling Language (UML). Alat yang digunakan dalam analisis dan perancangan sistem adalah Use Case Diagram, Activity Diagram, Squance Diagram, dan Class Diagram. Dari hasil pengujian dan wawancara evaluasi yang dilakukan dengan Ketua Posyandu Srikandi II, disimpulkan bahwa aplikasi eposyandu ini dapat memudahkan proses pengolahan, pencarian, dan pelaporan data kegiatan Posyandu Srikandi II. Pada pengembangan selanjutnya, diharapkan sistem informasi posyandu ini dilengkapi dengan fitur grafik pita KMS untuk memantau perkembangan berat badan anak.
Effect of Administration of Lidocaine at Body Temperature on Anesthesia Success in Rodent Model: A Behavioral and Electrophysiology Study
Authors:   Oral and Dental Diseases Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran., Kakooei Sina , Afarinesh Mohammadreza ,   Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran., Parirokh Masoud ,   Endodontology Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran., Nikzad Reza ,   Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran., Mostafavi Mahshid ,   Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran., Nekouei Amir ,   Endodontology Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran., Sabzalizadeh Mansoureh ,   Student Research Committee, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran., Sheibani Vahid ,   Student Research Committee, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Published: November 2021

Introduction: Success in anesthesia administration relieves the perception of pain during surgery. Lidocaine is the most commonly used local anesthetic agent in clinical medicine. Moreover, anesthetic agents’ temperature changes can influence cell membrane permeability. Here, the effectiveness of different temperatures of Lidocaine (Lid.) on anesthesia success rate has been investigated in rats. Methods: Wistar male rats were pretreated by fast injection of lidocaine or saline into the hind paw or intradermal cheek at Room Temperature (RT) and Body Temperature (BT) (22°C and 37°C, respectively). Then, rat behaviors were evaluated by formalin-induced hind paw pain and orofacial pain tests, respectively. Moreover, using a single-unit recording technique, the spontaneous activity of the marginal nerve was recorded at room temperature in the RT-Lid. and BT-Lid. groups. Results: Data analysis revealed that lidocaine had significant antinociceptive effects in both the BT-Lid. and RT-Lid. groups compared to the control groups (P<0.05). Also, the number of spikes in the BT-Lid. and RT-Lid. groups were significantly lower than their baselines (P<0.05). However, lidocaine at body temperature decreased the total time spent licking the hind paw, the number of lip rubbings, and the number of spikes firing by about 10%-15% compared to room temperature. Conclusion: In both behavioral and neural levels of the study, our results showed that an increase in the temperature of lidocaine toward body temperature could increase anesthesia success rate compared to administration of lidocaine at room temperature. These findings can be considered in the treatment of patients.
Proportioning Design of Foamed Concrete Mixed with Recycled Micro-powder of Construction Waste
Authors: Xie Hongyang , Dong Jianjun , Deng Yong , Dai Yiwen , Deng Mingwei
Published: November 2021

This paper presents a new kind of foamed concrete mixed with recycled micro-powder of construction waste which is helpful for saving resources, protecting the environment and achieving a sustainable development. An orthogonal experiment was designed to test the compressive strength of foamed concrete relatng to different factors, and the degree of influence were studied according to test result and range analysis of the factors. Using the efficacy coefficient method, the best mixture ratio was derived when both requirements of a quite light weight and a high strength were satisfied. XRD and SEM tests showed that the increase in compressive strength was due to the refinement of pores within the foamed concrete by the addition of recycled micronized powder.
Research on Examination of Construction Drawings of University Construction Projects
Authors: Dang Wenqiang
Published: November 2021

After completing the construction project approval, the universities will entrust a qualified design institute to carry out plan design, preliminary design and construction drawing design. Among them, the construction drawings are used to show the external shape, internal layout, detailed structure, and fixed facilities of the building, and its design depth meets the requirements for guiding construction. Construction drawings are an important basis for universities to compile bills of quantities, launch bidding, and organize construction. They are also a key factor for universities construction projects to achieve quality, investment, and schedule control goals. Therefore, the establishment of a complete construction drawing review mechanism to improve the quality of construction drawings is of great significance to the later project management.
Research Progress of Urban Public Service at Home and Abroad
Authors: Wei Lanyan
Published: November 2021

Public service facilities are an important part of China's harmonious and livable city construction and people's desire for a better life. The research topics of urban public service facilities allocation at home and abroad are different. It is found that foreign studies mainly focus on the location selection, accessibility, spatial equity and socio-economic effects of public service facilities allocation, while domestic studies pay more attention to the allocation standards of public service facilities and the optimization of layout, accessibility and spatial pattern. According to the characteristics of research at home and abroad, this paper reviews the literature respectively, and finally reflects on the differences of configuration research at home and abroad.
Analysis of Warning Threshold of Tunnel Monitoring and Measurement Based on Probability Statistics
Authors: Qian Jianbing
Published: November 2021

In the process of tunnel construction, data on deformation monitoring magnifies the direct reflection of the stability of tunnel structure, and the setting of early warning value is more related to the safety of project construction. In this paper, a tunnel project is taken as an example, and based on a large number of previous engineering practices and the statistical characteristics of monitoring data, the probability statistics method is used to obtain the warning threshold, which is used to give suggestions for the construction of the tunnel project and provide technical reference for the monitoring and warning management of similar tunnel construction.