bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioinformatic Databases
Authors: Herbert Katherine G. , Spirollari Junilda , Wang Jason T. L. , Wang Jason T. L. , Piel William H. , Westbrook John , Barker Winona C. , Hu Zhang‐Zhi , Wu Cathy H.
Published: December 2007

Biological database research encompasses many topics, such as biological data management, curation, quality, integration, and mining. Biological databases can be classified in many different ways, from the topic they cover, to how heavily annotated they are or which annotation method they employ, to how heavily annotated they are or which annotation method they employ,. to how heavily annotated they are or which annotation method they employ, to how highly integrated the database is with other databases. Popularly, the first two categories of classification are used most frequently. For example, there are archival nucleic acid data repositories (GenBank, the EMBL Data Library, and the DNA Databank of Japan) as well as protein sequence motif/domain databases, like PROSITE, that are derived from primary source data.

Modern biological databases comprise not only data, but also sophisticated query facities and bioinformatic data analysis tools; hence, the term “bioinformatic databases” is ofter used. This article presents information on some popular bioinformatic databased available online, including sequence, phylogenetic, structure and pathway, and microarray databases. It highlights features of these databases, discussing their unique charateristics, and focusing on types of data stored and query facilities available in the databaes. The concludes by summarizing important research and development challenges for these databases, namely knowledge discovery, large‐scale knowledge integration, and data providence problems.
Proofs of Correctness in Mathematics and Industry
Authors: Barendregt Henk
Published: December 2007

Quality of a product needs verification. If the product is complex, this verification cannot be done “by hand,” but one needs tools. The question then arises how those tools are being checked. Eventually quality comes from a careful specification and design methodology. Correctness is based on a mathematical proof that the design meets its specification. As mathematical proofs become long and complex themselves, we also need a tool to verify proofs. In order to prevent an infinite regress, this last tool must have a basic simplicity. Indeed, mathematical assistants that help users to develop and verify proofs are build on the current foundational logical systems that can be described in a couple of pages.

It is expected that within a couple of decades, the use of reliable mathematical assistants will be widespread and will help the human user to learn, develop, teach, communicate, referee, and apply mathematics. Computer‐verified correctness will probably become one of the most important applications of mathematics and computer science.
Run‐In Period
Authors: Berger Vance W. , Durkalski Valerie L.
Published: December 2007

Defining the study population is a critical step in clinical trial design. Ideally, the goal should be to choose a population who best represent the target population in a clinical setting, which in turn should be that segment of the population most likely to derive benefit. Because prespecified criteria cannot always predict which patients will and will not derive benefit, run‐in periods, which may be used for other reasons as well, are often incorporated into the design to enrich the sample by detecting and excluding a subgroup of the study population that is less likely to respond to the intervention. We review the definition, objective, and impact of run‐in periods on clinical trial conduct and results.
Multinational (Global) Trial
Authors: Snapinn Steven M.
Published: December 2007

Multinational clinical trials are trials conducted in more than one country using a common protocol. They have become increasingly common and have many advantages, such as access to a large patient population and the potential to obtain a broadly generalizable conclusion. However, these trials also have a number of practical difficulties, such as differences among the countries in language, import/export procedures, and regulatory and legal requirements. In addition, country‐by‐treatment interactions have frequently been found in these trials, leading to difficulties in interpreting the results. For example, the MERIT‐HF trial, which evaluated metoprolol in patients with heart failure, found an overall hazard ratio for total mortality of 0.66, but a hazard ratio of 1.05 in the United States. There is particular concern that differences among countries hinder the ability to evaluate the cost effectiveness of an experimental treatment.
Optimizing Schedule of Administration in PhaseIClinical Trials
Authors: Braun Thomas M. , Thall Peter F.
Published: December 2007

Historically, phase I clinical trials of new agents have been designed to find a safe dose from a small set of possible doses. Typically, toxicity is defined based on one or possibly two cycles of chemotherapy so that it can be scored relatively quickly after the start of therapy. The study treats cohorts of patients according to an outcome‐adaptive statistical design or algorithm for choosing successive doses, and the resulting data are used to determine an acceptable or maximum tolerable dose (MTD). However, in most clinical settings, physicians administer multiple courses of an agent to a patient and monitor long‐term toxicity that may be related to the agent's cumulative effects. Furthermore, some patients may receive one or more modifications or delays of their planned treatment course due to low‐grade (non–dose limiting) toxicity from previous administrations. To address these situations, we have proposed a new paradigm for phase I clinical trials that determines a maximum tolerable schedule (MTS) of administration, rather than a conventional MTD (Braun, Yuan, and Thall, 14). The design is based on the time to toxicity of each patient rather than a binary indicator. The model and method account for the patient's entire sequence of administrations, with the overall hazard of toxicity modeled as the sum of a sequence of dose‐dependent hazards, each associated with one administration. As patients are enrolled, data monitoring and decision making are done continuously throughout the trial using an outcome‐adaptive Bayesian design that optimizes the schedule in terms of the overall risk of toxicity. We illustrate this new methodology with a clinical trial in allogeneic bone marrow transplantation.
Application of New Designs in PhaseITrials
Authors: Garrett‐Mayer Elizabeth
Published: December 2007

In recent years, novel designs have been introduced for dose‐finding studies in phase I clinical trials. Most of these are based on mathematical models of the relationship between dose and toxicity. Though these may appear more technical than more commonly used algorithmic designs, the novel designs tend be better for many reasons including smaller sample size, more precise and accurate estimate of the desired dose, fewer patients treated at unsafe levels, and more patients treated at efficacious doses. Several of these novel designs are discussed. The continual reassessment method is an adaptive approach that uses the information gathered on early patients in the trial to make decisions about the dose for patients treated later in the trial. Adaptive Bayesian designs behave in a similar way, but the framework in which they are developed differs. A design in which efficacy and toxicity are both used to determine an optimum dose is also discussed.
Vaccine
Authors: Chan Ivan S. F.
Published: December 2007

Vaccines are primarily developed to prevent infectious diseases. They have been given to millions of people worldwide and contributed significantly to the improvement in public health. This article provides an overview of the clinical development of vaccines in terms of efficacy, immunogenicity, and safety assessment. The high expectation for the benefit‐to‐risk ratio required for developing preventive vaccines generates some unique challenges in the design and analysis of vaccine clinical trials. We will briefly discuss these challenges and illustrate with real examples.
Dose Finding Studies
Authors: Bretz Frank , Pinheiro José C.
Published: December 2007

Determining an adequate dose level for a drug and, more broadly, characterizing its dose–response relationship are key objectives of clinical drug development. If the dose is set too high, safety and tolerability problems are likely to result, whereas selecting too low a dose makes it difficult to establish adequate efficacy in the confirmatory phase, possibly leading to a failed program. It is well known that many potentially useful drugs have been discarded, and much time and resources have been wasted by pharmaceutical companies because of incorrect dosing. In addition, many marketed drugs have needed to have their label changed due to inappropriate, generally excessive, initial dose recommendations. A variety of issues must be considered when planning and analyzing a dose‐finding study so as to ensure it produces useful information for decision making. We describe key statistical methodologies for designing and analyzing clinical dose‐finding studies. These methodologies can be classified into different categories: multiple comparison procedures (including trend tests), modeling techniques, hybrid methods combining the previous two approaches, and adaptive dose‐finding strategies.
Computer‐Assisted Data Collection
Authors: Gabel Tim J. , Pedrazzani Susan D. , Day Orin A.
Published: December 2007

Computer‐assisted data collection methods have been widely used in the government survey and market research industries but have not been as prominent in the clinical research setting, which relies heavily on the use of paper‐based case report forms. In many clinical studies, respondents typically use paper forms to provide self‐reported data for the study. These forms are then converted to electronic format by data‐entry or clinical data management systems suitable for electronic data capture. Methods such as audio computer‐assisted self‐interviewing (A‐CASI) and telephone audio computer‐assisted self‐interviewing (T‐ACASI) may be particularly helpful in collecting high‐quality patient‐reported data, especially in Phase IV and postmarketing surveillance studies. This article introduces the primary considerations for using A‐CASI or T‐ACASI and provides insights into the management of data collected with these methods. It describes some of the advantages and data management efficiencies inherent in computer‐assisted interviewing systems and concludes with specific examples of successful use of these approaches in clinical studies.
Aligned Rank Test
Authors: McNeil Rebecca B. , Woolson Robert F.
Published: December 2007

Aligned rank tests are an intuitive rank‐based approach to the evaluation of an experimental treatment effect in blocked or stratified data. Their interblock ranking foundation yields an efficiency advantage relative to comparable tests constructed from intrablock rankings such as Friedman's test. Both exact and asymptotic tests of the null hypothesis are available with this approach. We present a general overview of the history and construction of aligned rank tests, and provide an example in selected data from a clinical trial of high‐dose vitamin D supplementation.
Characterization of Organic Solar Cells: the Importance of Device Layout
Authors: Cravino A. , Schilinsky P. , Brabec C. J.
Published: December 2007

Easily adjustable parameters such as area and design can affect the determination of the efficiency of donor–acceptor organic solar cells. Devices with crossing electrodes and unpatterned (semi)conducting organic layers can collect a non‐negligible current from regions usually not considered as part of the photovoltaic element, a fact that might lead to an overestimation of the power conversion efficiency.
Pulsed Laser Deposition and Electrochemical Characterization of LiFePO4–Ag Composite Thin Films
Authors: Lu Z. G. , Cheng H. , Lo M. F. , Chung C. Y.
Published: December 2007

A simple approach is proposed to enhance the electrical conductivity of olivine‐structured LiFePO4 thin films by uniformly dispersing small fractions of highly conductive silver (ca. 1.37 wt %) throughout the LiFePO4 film. In this approach, a highly densified (>85 %) LiFePO4–Ag target was first fabricated by coating conductive silver nanoparticles onto the surfaces of hydrothermally synthesized LiFePO4 ultrafine particles by a soft chemical route. Pulsed laser deposition (PLD) was then employed to deposit LiFePO4–Ag composite thin films on the Si/SiO2/Ti/Pt substrates. The PLD experimental parameters were optimized to obtain well‐crystallized and olivine‐phase pure LiFePO4–Ag composite thin films with smooth surfaces and homogeneous thicknesses. X‐ray diffraction (XRD), scanning electron microscopy (SEM), Raman spectrometry (Raman), X‐ray photoelectron spectroscopy (XPS), DC conductivity measurements, cyclic voltammetry(CV), as well as galvanostatic measurements were employed to characterize the as‐obtained LiFePO4–Ag composite films. The results revealed that after silver incorporation, the olivine LiFePO4 film cathode shows a superior electrochemical performance with a good combination of moderate specific capacity, stable cycling, and most importantly, a remarkable tolerance against high rates and over‐charging and ‐discharging.
Inside Front Cover: Polyvinylpyrrolidone‐Directed Crystallization of ZnO with Tunable Morphology and Bandgap (Adv. Funct. Mater. 18/2007)
Authors: Zhang J. , Liu H. , Wang Z. , Ming N. , Li Z. , Biris A. S.
Published: December 2007

A biomimetic approach for the shape‐selective synthesis of ZnO particles with controlled band gaps and morphologies at low temperatures is reported by Jianhui Zhang and co‐workers on p. 3897. Shape‐selective synthesis of ZnO is achieved by selective passivation of specific ZnO facets. Up to fifteen types of high‐purity ZnO structures were produced in this manner, allowing adjustment of room‐temperature photoluminescence and band gap.

A novel polyvinylpyrrolidone (PVP)‐directed crystallization route is successfully developed for the shape‐selective synthesis of ZnO particles with distinctive shapes, including monolayer, bilayer, and multilayer structures, gears, capped pots, hemispheres, and bowls, at temperatures as low as 32 °C. This route is based on exploiting a new water/PVP/n‐pentanol system. In the system, PVP can greatly promote ZnO nucleation by binding water and direct ZnO growth by selectively capping the specific ZnO facets, which is confirmed by IR absorption spectra. The bandgap of the ZnO particles is readily tuned by modifying the product morphology by adjusting the PVP chain length, PVP amount, water volume, and reaction temperature. The remarkable ZnO structures and the biomimetic method demonstrated here not only expand the structures and applications of ZnO but also provide a new approach to explore the unusual structures for novel physicochemical properties and technological applications. Furthermore, the novel ZnO/Au/ZnO sandwich structure is successfully fabricated by inserting a Au plate into the bilayer ZnO structure.
Comparison of crystallization behaviors of poly(ε‐caprolactone) in confined environment with that in bulk
Authors: Wu Tongfei , Zhang Xikui , Yang Guisheng
Published: December 2007

The spatial confinement of poly(ε‐caprolactone) (PCL) in the matrix of PMMA was synthesized by insitu polymerization and characterized by WAXD and SEM. The nonisothermal crystallization behavior and the kinetics of PCL in PMMA/PCL (85/15) blend and pure PCL were investigated by means of DSC. Jeziorny and Ozawa's theoretical prediction methods were used to analyze the crystallization kinetics. The melting behavior after cooling was also studied. There was an additional interesting phenomenon of double‐melting peak for pure PCL. Peaks at lower temperature shifted to lower temperature, and peaks at higher temperature did not shift with the increasing cooling rate. This behavior can be due to recrystallization. For the high‐crystallization activity energy and low‐crystallization rate, PCL in bulk would recrystallize during the melting process, and displayed a double‐melting behavior. Under spatial confinement of the rigid PMMA, PCL had much lower crystallization activity energy and had only one melting peak. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
An in vitro recombination method to convert restriction‐ and ligation‐independent expression vectors
Authors: Guo Feng , Chiang Ming‐Yi , Wang Yingtong , Zhang Yu‐Zhu
Published: December 2007

In recent years, restriction‐less recombination cloning systems based on site‐specific recombinase with high efficiency have been proven to be very successful. Thus, it is desirable to convert existing conventional vectors to recombination vectors. In this report, we describe the conversion of a set of widely used conventional vectors to Gateway® recombination expression vectors. An attB cassette flanked by several restriction enzyme sites was inserted in a cloning vector, and then subcloned into existing vectors to be converted to construct intermediate vectors containing the attB cassette, which were then converted to recombination expression vectors by in vitro recombination. The intermediate vectors generated in this study can be used for releasing the attB cassette to convert other vectors using the same protocol described here. With the increasing number of recombination vectors constructed with this protocol, the likeliness of releasing the attB cassette from an existing vector, rather than synthesizing it with PCR, will increase. The final expression vectors can also be used for releasing the attR cassette for constructing new vectors.
Analytical approach for the extraction of recombinant membrane viral glycoprotein from stably transfected Drosophila melanogaster cells
Authors: Astray Renato M. , Augusto Elisabeth , Yokomizo Adriana Y. , Pereira Carlos Augusto
Published: December 2007

Parameters for storage, lysis and concentration of Drososphila melanogaster Schneider 2 (S2AcRVGP) cells expressing the recombinant rabies virus glycoprotein (RVGP) were studied with regard to RVGP quantification by ELISA, for productivity evaluation and future purification. Lysis buffers were formulated with Tris, NaCl, glycerol, EDTA, KCl, Na2PO4, MgCl2, PMSF and NP‐40 or CHAPS. S2AcRVGP cells (107 cells at the exponential growth phase) were frozen at –20°C as a dry pellet, suspended in buffer (B) formulations or after treatment with lysis buffer (LB) formulations. They were then thawed as cell pellets or with B formulations or PBS at 4°C or at room temperature and then lysed with LB formulations. For RVGP quantification by ELISA, a protocol was chosen of cell preparation including cell freezing as dry pellet, cell thawing at 4°C with B4 (Tris, NaCl, MgCl2, PMSF) and cell lysis with the LB4 (B4 + NP‐40) since it fulfilled requirements of high RVGP detection, and was easily performed with mixtures freezing quickly, and a cost‐saving LB formulation could be used. Using these established conditions, we examined the optimal cell concentration for RVGP quantification by ELISA. Results showed that an increase in the RVGP detection (from 62.5 to 1083 ng/107 cells) paralleled a decrease in the cell number (3 ·107 – 105 cells) used. The NP‐40 concentration present in the LB4 was further investigated as a function of the cell number used for sample preparation. Previous results were confirmed indicating that higher NP‐40 concentrations led to a decreased detection of RVGP. Altogether our data clearly pointed out the crucial effects of cell freeze, thaw, lysis and concentration on immune detection of recombinant membrane glycoproteins and can be useful as a guideline for sample preparation for this purpose.
The Anion Distribution in Zr7O8N4
Authors: Bredow Thomas , Lerch Martin
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Single‐Crystal Synthesis, Structure Analysis, and Physical Properties of the Calcium Ferrite‐Type NaxTi2O4 with 0.558 < x < 1.
Authors: Takahashi Yasuhiko , Kataoka Kunimitsu , Ohshima Ken‐ichi , Kijima Norihito , Awaka Junji , Kawaguchi Kenji , Akimoto Junji
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure and Basic Magnetic Properties of the Honeycomb Lattice Compounds Na2Co2TeO6 and Na3Co2SbO6.
Authors: Viciu L. , Huang Q. , Morosan E. , Zandbergen H. W. , Greenbaum N. I. , McQueen T. , Cava R. J.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Crystal Structures and Properties of the Trimetaphosphimates Na2M(PO2NH)3×2H2O with M: K, Tl.
Authors: Sedlmaier Stefan J. , Johrendt Dirk , Oeckler Oliver , Schnick Wolfgang
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Centered Indium Cubes as Structural Motifs in SrRh2In8 and SrIrIn4.
Authors: Muts Ihor R. , Zaremba Vasyl I. , Poettgen Rainer
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structure and Properties of (H9O4)2 [Mo2(S2)2X8] (X: Cl, Br).
Authors: Sokolov Maxim N. , Abramov Pavel A. , Peresypkina Eugenia V. , Virovets Alexander V. , Uvarov Nikolai F. , Gerasko Olga A. , Fedin Vladimir P.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Crystal Structure of the New Quaternary Subnitride Na15Li8Ba12N6.
Authors: Smetana Volodymyr , Babizhetskyy Volodymyr , Vajenine Grigori V. , Simon Arndt
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thiosilicates of the Rare‐Earth Elements. Part 4. The quasi‐Isostructural Compounds NaSm3S3[SiS4] (I), CuCe3S3[SiS4] (II), Ag0.63Ce3S2.63Cl0.37 [SiS4] (III) and Sm3S2Cl[SiS4] (IV) — Synthesis, Crystal Structure and Investigations of the Silver‐Cation Motion.
Authors: Hartenbach Ingo , Nilges Tom , Schleid Thomas
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Dimensional Array of Two‐ and Three‐Center Cation—Cation Bonds in the Structure of Li4 [(UO2)10O10(Mo2O8)].
Authors: Alekseev Evgeny V. , Krivovichev Sergey V. , Malcherek Thomas , Depmeier Wulf
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Oxidation of SrCoO3‐δ.
Authors: Karvonen Lassi , Raesaenen Samuli , Yamauchi Hisao , Karppinen Maarit
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
AgGaS2‐Type Photocatalysts for Hydrogen Production under Visible Light: Effects of Post‐Synthetic H2S Treatment.
Authors: Jang Jum Suk , Choi Sun Hee , Shin Namsoo , Yu Chungjong , Lee Jae Sung
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Eu3(AsS4) and AxEu3‐yAs5‐zS10 (A: Li, Na): Compounds with Simple and Complex Thioarsenate Building Blocks.
Authors: Bera Tarun K. , Iyer Ratnasabapathy G. , Malliakas Christos D. , Kanatzidis Mercouri G.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses, Crystal Structures, UV‐Vis Spectra and First NMR Spectra of New Potassium Salts of Chalcogenogermanates.
Authors: Melullis Maike , Dehnen Stefanie
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Structural Characterization of a γ‐Keggin‐Type Dimeric Silicotungstate with a Bis(μ‐hydroxo) Dizirconium Core [(γ‐SiW10O36)2Zr2 (μ‐OH)2]10‐.
Authors: Yamaguchi Syuhei , Kikukawa Yuji , Tsuchida Kazutaka , Nakagawa Yoshinao , Uehara Kazuhiro , Yamaguchi Kazuya , Mizuno Noritaka
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hydrothermal Synthesis and Crystal Structure of the Ni2(C4H4N2) (V4O12)(H2O)2 and Ni3(C4H4N2)3 (V8O23) Inorganic—Organic Hybrid Compounds. Thermal, Spectroscopic and Magnetic Studies of the Hydrated Phase.
Authors: Larrea Edurne S. , Mesa Jose L. , Pizarro Jose L. , Arriortua Maria I. , Rojo Teofilo
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemoenzymatic Dynamic Kinetic Resolution of Allylic Alcohols: A Highly Enantioselective Route to Acyloin Acetates.
Authors: Bogar Krisztian , Hoyos Vidal Pilar , Alcantara Leon Andres R. , Baeckvall Jan‐E.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Insights into the Formation of Symmetrical Trimers of Dialkylated Ketenes Starting from Acid Chloride Precursors.
Authors: Saaidi Pierre‐Loic , Doridot Gabriel , Jeanneau Erwann , Hasserodt Jens
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
SDS/Ac2O/H2O: Surfactant‐Mediated Cleavage of Imines with Acetic Anhydride to Carbonyls and Acetanilides in Water.
Authors: Sharma Saikat Das , Gogoi Pranjal , Boruah Monalisa , Konwar Dilip
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Interaction of Aminoazoles with Meldrum′s Acid and Dialkyl Ketones or Cyclohexanone.
Authors: Lipson V. V. , Borodina V. V. , Shirobokova M. G. , Desenko S. M. , Shishkin O. V. , Zubatyuk R. I.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Site‐Specific Preparation of 4‐Substituted‐6‐fluoro(carboalkoxyl)benzo[b]furans and Benzo[b]thiophenes via Base‐Catalyzed Cyclization of Enyne Derivatives.
Authors: Wang Yi , Burton Donald J.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
DDQ Catalyzed Benzylic Acetoxylation of Arylalkanes: A Case of Exquisitely Controlled Oxidation under Sonochemical Activation.
Authors: Kumar Vinod , Sharma Abhishek , Sharma Meenakshi , Sharma Upendra K. , Sinha Arun K.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tetrabutylammonium Fluoride Induced Dehydrobromination of Vinyl Bromides to Terminal Acetylenes.
Authors: Okutani Masaru , Mori Yuji
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rapid and Efficient Microwave‐Assisted Synthesis of Highly Sulfated Organic Scaffolds.
Authors: Raghuraman Arjun , Riaz Muhammad , Hindle Michael , Desai Umesh R.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Pyridine N‐Oxides with Grignard Reagents: A Stereodefined Synthesis of Substituted Dienal Oximes.
Authors: Andersson Hans , Wang Xiaoyang , Bjoerklund Mikael , Olsson Roger , Almqvist Fredrik
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Preparation of N‐Chirogenic Tertiary Amine Oxides.
Authors: Suzuki Ichiro , Kerakawauchi Ran , Hirokawa Takako , Takeda Kei
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
DBU‐Mediated Ireland—Claisen Rearrangement of Allyl Alk‐3‐enoates: An Efficient Synthesis of 2‐Ethylidene‐γ,δ‐unsaturated Carboxylic Acids.
Authors: Li Yunxia , Goeke Andreas , Wang Ruiyao , Wang Quanrui , Frater Georg
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Preparation of 2‐Methyl‐1‐cyclopentene‐1‐carboxylic Acid, a Versatile Synthetic Building Block.
Authors: Benetti Simonetta , De Risi Carmela , Ferroni Francesco , Pollini Gian P.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Biological Evaluation of N‐Acetyl‐β‐aryl‐1,2‐didehydroethylamines as New HIV‐1 RT Inhibitors in vitro.
Authors: Cheng Pi , Jiang Zhi‐Yong , Wang Rui‐Rui , Zhang Xue‐Mei , Wang Qian , Zheng Yong‐Tang , Zhou Jun , Chen Ji‐Jun
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemoselective and Efficient Carbomethoxylation of the Alcoholic Chain of Phenols by Dimethyl Carbonate (DMC).
Authors: Bernini Roberta , Mincione Enrico , Crisante Fernanda , Barontini Maurizio , Fabrizi Giancarlo , Gentili Patrizia
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mild and Selective Nitration of Phenols by Zeofen.
Authors: Bigdeli Mohammad A. , Heravi Majid M. , Nemati Firouzeh
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Obtaining 4‐Vinylphenols by Decarboxylation of Natural 4‐Hydroxycinnamic Acids under Microwave Irradiation.
Authors: Bernini Roberta , Mincione Enrico , Barontini Maurizio , Provenzano Gianfranco , Setti Leonardo
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Facile and Efficient Conversion of Aldehydes into 1,1‐Diacetates (Acylals) Using Iron(III) Fluoride as a Novel Catalyst.
Authors: Kamble V. T. , Tayade R. A. , Davane B. S. , Kadam K. R.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regioselective Synthesis of Functionally Crowded Benzenes at Room Temperature Through Ring Transformation of 2H‐Pyran‐2‐ones.
Authors: Singh Fateh Veer , Kumar Vijay , Goel Atul
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective and Diastereoselective Syntheses of Cyanohydrin Carbonates.
Authors: Belokon Yuri N. , Clegg William , Harrington Ross W. , Ishibashi Eisuke , Nomura Hiroshi , North Michael
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel 3‐Amino‐2‐(4‐chloro‐2‐mercaptobenzenesulfonyl)guanidine Derivatives as Potential Antitumor Agents.
Authors: Brzozowski Zdzislaw , Saczewski Fanciszek , Slawinski Jaroslaw
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Highly Efficient Iodine‐Catalyzed Hydroarylation of Arenes with Styrenes.
Authors: Chu Cheng‐Ming , Huang Wan‐Ju , Liu Ju‐Tsung , Yao Ching‐Fa
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Conversion of 1,1‐Dibromoalkenes into Internal Alkynes by Sequential Suzuki—Miyaura and Dehydrobromination Reactions.
Authors: Chelucci Giorgio , Capitta Francesca , Baldino Salvatore , Pinna Gerard A.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Silica‐Immobilized CuI: An Efficient Reusable Catalyst for Three‐Component Coupling Reaction of Aldehyde, Amine and Alkyne.
Authors: Likhar Pravin R. , Roy Sarabindu , Roy Moumita , Subhas M. S. , Kantam M. Lakshmi , De Rajib Lal
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 1‐Indanones via Intramolecular Cyclodehydration of 3‐Arylpropionic Acids Catalyzed by Heteropoly Acid as Heterogeneous Catalyst.
Authors: Lan Kun , Shan Zi‐Xing
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel Nickel(0)‐Catalyzed Cascade Ullmann—Pinacol Coupling: From o‐Bromobenzaldehyde to trans‐9,10‐Dihydroxy‐9,10‐dihydrophenanthrene.
Authors: Lin Shuang‐zheng , Chen Qing‐an , You Tian‐pa
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Oxidative Radical Spirolactamization.
Authors: Ibarra‐Rivera Tannya R. , Gamez‐Montano Rocio , Miranda Luis D.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Catalytic Synthesis of Aziridines Without the Usual Byproducts.
Authors: Mazumdar Arindam , Xue Zheng , Mayer Michael F.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Mild and Efficient C‐3 Allylic Alkylation of Indoles Catalyzed by FeCl3.
Authors: Liu Zhe , Liu Li , Shafiq Zahid , Wang Dong , Chen Yong‐Jun
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Structure of New Oxoindoles.
Authors: Macaev F. Z. , Radul O. M. , Shterbet I. N. , Pogrebnoi S. I. , Sucman N. S. , Malinovskii S. T. , Barba A. N. , Gdaniec M.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot and Solventless Synthesis of Ionic Liquids under Ultrasonic Irradiation.
Authors: Estager Julien , Leveque Jean‐Marc , Cravotto Giancarlo , Boffa Luisa , Bonrath Werner , Draye Micheline
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of Oxazolidin‐2‐one via (Chitosan‐Schiff Base)Cobalt(II)‐Catalyzed Oxidative Carbonylation of 2‐Aminoalkan‐1‐ols.
Authors: Liu Jianming , Sun Wei , Zheng Shuzhan , Xia Chungu
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of New 2‐Amino‐5‐hydroxymethyl‐2‐thiazolines.
Authors: Trofimova T. P. , Pushin A. N. , Proshin A. N. , Stash A. I. , Mandrugin A. A. , Fedoseev V. M. , Proskuryakov S. Ya.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and SAR of Tetrahydropyrrolo[1,2‐b][1,2,5]thiadiazol‐2(3H)‐one 1,1‐Dioxide Analogues as Highly Potent Selective Androgen Receptor Modulators.
Authors: Manfredi Mark C. , et al. et al.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Thiotetrazole Alkynylacetanilides as Potent and Bioavailable Non‐Nucleoside Inhibitors of the HIV‐1 Wild Type and K103N/Y181C Double Mutant Reverse Transcriptases.
Authors: Gagnon Alexandre , et al. et al.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Condensed Systems — Substituted Octahydrochromeno[2,3,4‐k,l]xanthylium Salts.
Authors: Nikishin A. Yu. , Fedotova O. V.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Perfluoro‐1‐ethylindan with SiO2/SbF5 and Skeletal Transformations of Perfluoro‐3‐ethylindan‐1‐one under the Action of SbF5 and SiO2/SbF5.
Authors: Zonov Yaroslav V. , Karpov Victor M. , Platonov Vyacheslav E.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Concise Asymmetric Synthesis of Torcetrapib (I).
Authors: Guino Meritxell , Phua Pim Huat , Caille Jean‐Claude , Hii King Kuok
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Properties of Azidostyrylquinolines.
Authors: Budyka M. F. , Biktimirova N. V. , Gavrishova T. N.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, in vitro and in vivo Cytotoxicity of 6,7‐Diaryl‐2,3,8,8a‐tetrahydroindolizin‐5(1H)‐ones.
Authors: Kimball F. Scott , Tunoori Ashok Rao , Victory Samuel F. , Dutta Dinah , White Jonathan M. , Himes Richard H. , Georg Gunda I.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Molecular Structure of 3‐(2‐Aryl‐2‐oxoethyl)‐3‐methoxy‐2‐oxo‐2,3‐dihydroimidazo[1,2‐]pyridine Hydrochlorides.
Authors: Aliev Z. G. , Atovmyan L. O. , Kataev S. S. , Zalesov V. V.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Properties of (6‐Methyl‐2‐oxo‐4‐thioxo‐1,2,3,4‐tetrahydro‐3‐pyrimidinyl)acetic Acid Methyl Ester.
Authors: Jakubkiene V. , Paulauskaite R. , Vainilavicius P.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selective Synthesis of Fluorinated Benzyl‐ or Phenylpyrimidines from the Heterocyclization of α‐Trifluoroacetylarylpropanenitriles.
Authors: Berber Hatice , Mirand Catherine , Derouin Francis
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ketene S,S‐Acetals in the Synthesis of Some New Fused Pyrimidine Derivatives.
Authors: Metwally M. A. , Desoky E. I. , Fawzy R. , Etman H. A.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Condensed Isoquinolines. Part 21. Condensation of o‐Bromomethylphenylacetonitrile with Substituted Anthranilic Acids.
Authors: Potikha L. M. , Kovtunenko V. A. , Kisil V. M.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The p‐(Dimethylamino)benzaldehyde Modification of Hantzsch Reaction: Synthesis of 6‐(1H‐Benzimidazol‐2‐yl)pyrido[2,3‐d]pyrimidino‐2,4(1H,3H)‐diones.
Authors: Dzvinchuk I. B. , Lozinskii M. O.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical Synthesis and Applications of Benzoboroxoles.
Authors: Gunasekera Dinara S. , Gerold Dennis J. , Aalderks Nathan S. , Chandra J. Subash , Maanu Christiana A. , Kiprof Paul , Zhdankin Viktor V. , Reddy M. Venkat Ram
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cascade Triple‐Aldehyde Addition of 1,2,3,4‐Tetrakis(pinacolatoboryl)but‐2‐ene: Stereoselective Synthesis of 2,3‐Bis(alkylidene)alkane‐1,5‐diols.
Authors: Shimizu Masaki , Shimono Katsuhiro , Hiyama Tamejiro
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Heterocyclization in the Reaction of Pyridine‐2‐selanyl Chloride with Styrene.
Authors: Borisov A. V. , Matsulevich Zh. V. , Osmanov V. K. , Borisova T. N. , Savikhina E. V.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Diastereoselective Synthesis of (E)‐gem‐Dimetalloalkenes Containing Boron and Germanium: An Easy Access to Alkyl Trimethylgermyl Ketones and Carboxylic Acids.
Authors: Bhat Narayan G. , Varghese Nisha
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Metachromins L—Q, New Sesquiterpenoid Quinones with an Amino Acid Residue from Sponge Spongia sp.
Authors: Takahashi Yohei , Kubota Takaaki , Fromont Jane , Kobayashi Jun'ichi
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Methyl Sarcophytoate.
Authors: Ichige Takahiro , Okano Yusuke , Kanoh Naoki , Nakata Masaya
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three New Clerodane Diterpenoids from the Bulbils of Dioscorea bulbifera L. var. sativa.
Authors: Teponno Remy Bertrand , Tapondjou Azefack Leon , Ju‐Jung Hyun , Nam Jung‐Hwan , Tane Pierre , Park Hee‐Juhn
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of the Core of Naturally Occurring anti‐HIV Isolitseane B.
Authors: Bremond Paul , Girardeau Elodie , Coquerel Yoann , Rodriguez Jean
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Withanolide Compounds from the Flower of Datura metel L.
Authors: Yang Bingyou , Wang Qiuhong , Xia Yonggang , Feng Weisheng , Kuang Haixue
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis, Stereochemical Reassignment, and Absolute Configuration of Chlorofusin
Authors: Lee Sang Yeul , Clark Ryan C. , Boger Dale L.
Published: December 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.