bluuebunny/crossref_metadata_2025 huggingface dataset:
Open Source-Based UAVs for STEAM Education: Some Case Studies
Authors:   Smart Systems Institute, National University of Singapore, Singapore, Sueda Koh , Yamazaki Atsuko K. , Nomura Makoto , Sakamoto Masayuki , Kato Yasuhiro , Hosaka Masanori
Published: October 2021

The importance of Science Technology, Engineering, Arts, and Mathematics (STEAM) education has been strongly recognized over the last few years. STEAM education requires an approach to integrate these disciples, and robots and unmanned aerial vehicles (UAVs) are often utilized as ideal tools for hands-on STEAM education. Over the past few years, open source-based fully autonomous UAVs have been priced below $100. This fact also has allowed UAV Research and Development (R&D) to bring reverse innovation in education. This paper introduces our projects contributing to local communities, including R&D and STEAM educational programs that exploit open-source UAV platforms. We describe three examples of STEAM educational programs using UAV technologies: a three-day scratch-build UAV workshop at the Kirirom Institute of Technologies in Cambodia, a sailing robot development project at a private STEAM education and fabrication lab for children, VIVISTOP Kashiwanoha in Chiba, Japan, and an ongoing project of UAV R&D at Japan Aviation Academy whose framework is going to be extended to a workshop for local children in Ishikawa, Japan, with a local board of education.
An Investigation of the Learning Motivation of Student Studying Accounting Courses in China
Authors:   Beijing Institute of Technology, Zhuhai, China, Ho Miu Hing , Fido Dean , Simonovic Boban
Published: October 2021

Since the 1980s, concerns within the accounting profession have asked whether the accounting curriculum aligns with evolving accounting practice and the preparation of students for working in accounting field. In recent years, the accountancy profession has played a vital role in the growth of China’s economy, and so identifying the motivation of college students to study accounting in China and their inclination to enter the accounting profession is paramount. This paper investigates the learning motivation of students studying accounting in China through the use of self-administered questionnaires. Non-probability sampling technique was used in this study. A total of 103 questionnaire responses were collected and underwent descriptive and correlation analysis. Findings indicated that undergraduate accounting students were mainly motivated by their concerns about their future career and qualification, altruism, enjoy social life, and self-exploration. These findings are consistent with the self-determined theory about self-identity as an accounting professional, and support the expectancy-value theory in the value of studying accounting to the career aspiration, and concurs with the achievement goal theory in achieving the professional qualifications and personal growth. Findings from this study have implications for helping students to understand their motivations to study accounting and their suitability of entering the accounting profession. Accounting professional bodies may also use the findings reported here to inform on member recruitment strategies, whilst facilitating education providers’ assessment of suitability for candidates to studying accounting and the design of curriculum and teaching strategies.
Knowing the Skeptic
Authors: McCreary Michael
Published: October 2021

Descartes may have produced the paradigmatic image of modern philosophy when he donned his winter dressing gown, settled into his favorite armchair by the fire, and began a private meditation by wondering whether the flame in front of him were anything more than a dream. Like most skeptical recitals, the force of Descartes’ method arises through the mobilization of best cases for knowing; that is, through casting doubt on something so certain that one begins to question one’s ability to know anything at all. By impugning precisely those axioms we held most assured, Descartes demonstrates philosophy’s propensity to challenge our most fundamental assumptions, yet he simultaneously leverages the significance of the philosophical enterprise against more everyday or ordinary claims to knowledge, that of course the fire really burns. In doing so, Descartes opens up the possibility that a critic of skepticism will be more inclined to doubt the sanity of philosophical inquiry than to admit that the flame, or the greater external world, may be nothing more than a dream, or the conjuring of an evil demon. So the profundity or inanity of philosophy seems to turn on the whim of human temperament, and in particular, on my reaction to the idea that I may be mistaken about everything I claim to know.
A rare case report on thyroid associated orbitopathy
Authors: Paul Leena , Rai Utkarsh
Published: October 2021

Thyroid associated orbitopathy (TAO) or graves disease is an autoimmune disorder associated with hyperthyroidism though few cases of hypothyroidism and euthyroidism are also found. Most common presentation is eyelid retraction followed by exophthalmos. Although TAO is more common in women, the proportion in men increases as severity increases. We report a case of young adult woman who presented with proptosis, severe ptosis in right eye and motility restriction in both eye with moderately painful swelling of right eyelid. CEMRI orbit revealed swelling of bilateral recti muscles with sparing of tendons which is characteristic of TAO. Thyroid profile showed hyperthyroid state, Clinical features were suggestive of orbital apex syndrome and diagnosis of TAO was based on orbital muscle changes in MRI. A course of methylprednisolone was given with tapering dose which improved proptosis, ptosis and extraocular movement on follow up.
Endometriosis impact on the course of pregnancy and obstetric outcomes
Authors: Zhabitska L.A. , Zhabitska L.A.
Published: October 2021

Today, the issues of the pregnancy course in women with endometriosis and endometriosis impact on obstetric outcome remain unresolved and insufficiently studied.Research objective: to study the association between endometriosis and pregnancy complications, adverse obstetric outcomes.Materials and methods. A retrospective cohort study comparing the incidence of pregnancy complications and adverse obstetric outcomes in 478 women with endometriosis (main group) and 544 women without endometriosis (control group). Complications of pregnancy and unfavorable obstetric outcomes were assessed, such as spontaneous miscarriage, ectopic pregnancy, vomiting of pregnant women, premature birth, caesarean section, pathological attachment of the placenta, postpartum hemorrhage and small for gestational age fetuses.Results. The study showed that pregnant women with endometriosis have an increased risk of spontaneous miscarriages compared to the control group: 89/478 (19.07 ± 1.13%) versus 87/544 (14.93 ± 0.49%) respectively (p < 0.001), ectopic pregnancy: 12/478 (2.84 ± 0.47%) versus 5/544 (0.97 ± 0.36%) respectively (p < 0.001); vomiting of pregnant women: 86/478 (17.85 ± 1.09%) compared with 16/544 (3.15 ± 0.34%) respectively (p < 0.001); premature birth: 72/478 (15.5 ± 1.03%) versus 55/544 (10.17 ± 0.30%) respectively (p < 0.001); increased frequency of caesarean section: 99/478 (20.44 ± 1.24%) versus 87/544 (15.5 ± 0.73%) respectively (p < 0.001) and pathological attachment of the placenta: 19/478 (4.31 ± 0.59%) versus 8/544 (1.46 ± 0.30%) respectively (p < 0.001).There was no association between endometriosis and postpartum hemorrhage and small gestational age of the fetus.Conclusions. Pregnant women with endometriosis have an increased risk of spontaneous miscarriages, ectopic pregnancy, vomiting of pregnant women, premature birth, caesarean section, pathological attachment of the placenta. The association established in our study between endometriosis and complications of pregnancy, unfavorable obstetric results requires further research to clarify the mechanisms of the results obtained.
Pregnancy during a pandemic: perinatal effects of prolonged stress and ways of correction
Authors: Antypkin Y.G. , Zhabchenko I.A. , Kovalenko T.M. , Lishchenko I.S.
Published: October 2021

This article presents current data about the perinatal effects of prolonged stress on pregnant women during the COVID-19 pandemic. The peculiarities of the postcovid syndrome in general and in the female population in particular are determined. Peculiarities of pregnancy and perinatal consequences after coronavirus infection, as well as manifestations of postcovid syndrome in this group of women are considered. There is an increase in the frequency of anxiety and depressive disorders in pregnant women and women in labor during the pandemic and their impact on the fetal brain and its subsequent mental state.The specific effects of long-term stress have been identified: it has become known that pregnant women during the pandemic are exposed to prolonged stress, which affects the course of gestation. Among the most common conditions under the stressors impact (illness of the woman or her close environment, loss of relatives and acquaintances, existence in limited physical and communication space, deterioration of financial condition, etc.) should be noted the increasing risk of abortion up to 17–28%; exacerbation during pregnancy of chronic somatic diseases (hypertension, diabetes, metabolic syndrome, chronic pancreatitis, neurological and mental illness, etc.); increase in body mass index on the eve of pregnancy and pathological weight gain; strengthening of nutritional deficiencies (folate, iron, magnesium, vitamin D, iodine, etc.).The timely detection and possible ways to correct these conditions are considered, given the transition to remote methods of monitoring pregnant women in quarantine. Organizational , treatment and prevention measures with inclusion of micronized progesterone, magnesium citrate, folate (metafolin) and vitamin D, as well as methods of psychoprophylaxis and psychotherapy are also proposed. Magnesium is of particular importance in pregnant women, it has neuroprotective and metabolic properties, in particular when used as a citrate in soluble form. The main directions of rehabilitation measures for pregnant women and women in labor after COVID-19 have been formulated.
Ageing well in public housing
Authors: Faulkner Debbie , Verdouw Julia , Cook Peta , Tually Selina , Liu Edgar , Judd Bruce , Barrie Helen , Coram Veronica
Published: October 2021

This research examines the policy and practice issues raised by increasing demand for public housing among older Australians, and how public housing authorities can support older tenants to age well. People aged 55 years and over now comprise 35 per cent of public housing tenants nationally, in the coming years it is expected the demand on the public housing system from lower income older households will increase significantly.
RESIDENTES DE ENFERMAGEM E A TERAPIA PELA ARTE
Authors: Freitas Bismarck Liandro de , Mello Rosâne , Santos Lucinda Maria Santiago Souza
Published: October 2021

Objetivo: relatar os resultados da terapia pela arte por meio de oficinas expressivas aos enfermeiros residentes. Método: estudo descritivo exploratório, de abordagem qualitativa, com análise temática, que apresenta a experiência sentida e vivenciada por sete profissionais enfermeiros do primeiro ano de residência, que participaram das oficinas expressivas em um hospital de grande porte localizado na cidade do Rio de Janeiro, Brasil. Resultados: surgiram os seguintes temas: o ambiente hospitalar como fator estressante; a arte como mecanismo catártico em meio ao sofrimento emocional; olhando para dentro e encontrando equilíbrio; o uso da arte como instrumento para relaxar, descontrair e adquirir novas experiências; conceito ampliado de saúde e doença. Considerações finais: a arte por meio das oficinas expressivas trouxe impactos positivos aos residentes de Enfermagem. A pesquisa mostra que é possível promover saúde por meio da arte.
Recreational Therapists’ Practice, Knowledge, and Perceptions Associated with Animal-Assisted Therapy
Authors: Barbosa Dunlap Kimberly , Miller Kimberly , Kinney Judy
Published: October 2021

Animal-assisted interventions have been implemented by health care professionals because of the therapeutic value of animal interactions. The purpose of this study was to survey Certified Therapeutic Recreation Specialists (CTRSs) to (a) determine the prevalence of Animal Assisted Interventions (AAI) implemented by recreational therapists, and (b) understand the knowledge and barriers to AAT implementation that exist for recreational therapists. A total of 123 Certified Therapeutic Recreation Specialists participated in the study (a 6.2% response rate). A significant difference was found in the AAT goal of improving social interaction by population. Those working in physical medicine and rehabilitation reported less improvement than those in behavioral health, geriatrics and community agencies. CTRSs indicated there is a need for additional education and trainings on AAT practice. Many CTRSs surveyed identified the lack of registered animal/handler teams in the area as a major barrier to implement AAT.
Competencias ciudadanas y sus políticas educativas en Hispanoamérica y Colombia
Authors: Montaña Contreras Deiscy , López Guio Angela Andrea
Published: October 2021

El artículo muestra una revisión documental sobre las competencias ciudadanas y las políticas públicas en Colombia y otros países hispanoamericanos, mediante la recopilación de artículos y el análisis de los discursos de las competencias como saber escolar. Desde una perspectiva metodológica, se rastrearon y se conceptualizaron categorías como: competencias, educación y políticas públicas. Se trabajó en tres etapas: la primera fue un acercamiento histórico y conceptual de las competencias ciudadanas a partir de los años 80 en Colombia y desde la promulgación de la constitución de 1991; en la segunda, se estudió el concepto de ciudadanía desde la vinculación del discurso teórico y experiencias en el aula en diferentes países de habla hispana; y finalmente, se evaluaron las implicaciones que el modelo neoliberal ha tenido tanto en las políticas educativas como en la formación de ciudadanos y su intervención en la educación superior. Como resultado, en el análisis de la categoría de políticas públicas y las competencias ciudadanas, se infiere una importante preocupación por enlazar de manera articulada y permanente el currículo educativo y los lineamientos establecidos por entes gubernamentales a la aplicación y regulación de dichas competencias, no como una cátedra más en las instituciones educativas establecidas para el mercado laboral, sino como un componente formativo fundamental para la construcción de ciudadanía, sin caer en la instrumentalización y en la ambigüedad de la noción de competencias y ciudadanía en el ámbito educativo actual.
Rede de proteção e violência: a atuação dos grupos armados e a gestão compartilhada da favela no Rio de Janeiro |Network of protection and violence: the actions of armed groups and the shared management of the favela in Rio de Janeiro
Authors: Fernandes Ionara dos Santos
Published: October 2021

O artigo tem por objetivo analisar a rede de proteção e violência pelos grupos armados nas favelas e espaços populares, com base nos relatos e vivências de crianças e adolescentes pobres e moradoras desses territórios. Entende-se por grupos armados, o institucional, ou seja, a polícia e os vendedores varejistas de drogas. É com base nas suas práticas, que compreendemos que ambos os grupos partilham o controle dos territórios de maneira violenta e ao mesmo tempo, garantem a proteção aos moradores, seus pares e rivais, numa dinâmica de cooperação e conflito, compartilhando a gestão do espaço e das relações sociais.
Ensino de arte e as danças brasileiras
Authors: Santinho Gabriela Di Donato Salvador , Santos Vanderlei José dos
Published: October 2021

O presente texto apresenta o trabalho realizado em uma escola da comunidade quilombola Furnas do Dionisio, em Jaraguari -MS, e foi pautado nas danças afro-brasileiras e na metodologia proposta pelo Grupo de Pesquisa em Danças Populares Brasileiras Renda que Roda, da Universidade Estadual de Mato Grosso do Sul. A proposta é destacar essas danças como propulsoras de conhecimentos sensíveis e legítimos para a educação.
Trajetórias de profissionalização docente da mulher educadora: monitoras de creche em Naviraí, MS
Authors: Montiel Larissa Wayhs Trein , Campos Míria Izabel
Published: October 2021

O atendimento coletivo das crianças nas creches no Brasil se pautou pela ideia preconcebida de que a mulher, por sua natureza feminina, seria mais bem preparada para assumir as funções naqueles espaços.  Nesse contexto, o objetivo geral neste texto foi dar visibilidade às trajetórias de profissionalização docente de mulheres educadoras de Naviraí, Mato Grosso do Sul. Para tanto, elencaram-se como objetivos específicos saber quando se tornaram monitoras de creche; quais motivos e/ou interesses as levaram à escolha profissional; como questões de gênero permearam e refletiram nas trajetórias de vida e profissão; e de que forma compreenderam a necessidade de uma profissionalização docente para se estabelecerem na carreira. Utilizou-se como recurso metodológico a História Oral temática, tendo sido realizadas entrevistas, as quais foram analisadas à luz do referencial teórico eliasiano. Percebeu-se que as políticas educacionais pensadas para o atendimento à criança pequena geraram uma alteração na carreira destas profissionais, e isso se refletiu em suas trajetórias de formação docente. Compreendeu-se que rememorar os aspectos envolvidos no percurso de suas vidas e trajetórias profissionais possibilitou o entendimento de como as figurações, isto é, as redes de interdependência, foram constituídas pelas mulheres educadoras e ao mesmo tempo as constituíram, trazendo à tona questões de gênero e poder inerentes aos diferentes tempos e espaços de trabalho e formação.
Effects of marine oligomeric polyphenols on body composition and physical ability of elderly individuals with sarcopenia: a pilot study
Authors: Kwon Il-Su , Park Deuk-Su , Shin Hyeon-Cheol , Seok Myung-Gyu , Oh Jae-Keun
Published: October 2021

[Purpose] We aimed to identify the effects of marine oligomeric polyphenol (MOP) intake in elderly individuals with sarcopenia.[Methods] Older adults (aged 65 years or older) were recruited based on the diagnostic criterion for sarcopenia and were randomly assigned to the MOP intake group (n=10) or the placebo (PBO) intake group (n=10). To determine the effect of MOP intake received for four weeks, the pre- and post-intake body composition (weight, skeletal muscle mass, and bone density) and senior fitness tests were assessed.[Results] Our results showed there were significant differences in the skeletal muscle mass (p =0.039), bone density (p =0.020), fat-free mass index (p =0.026), and 2.4 m up and go test (p =0.001) between pretest and post-test. There was a significant difference between the pre-test and post-test and an interaction effect for the one-leg stand test (p =0.010 and p =0.049, respectively). However, there were no significant differences in body fat percentage, calf circumference, grip strength, or the chair rise test.[Conclusion] Some variables exhibited significant differences in the pre- and post-assessments, and there was an interaction effect for the one-leg stand. However, this was insufficient to prove the effectiveness of MOP intake in improving sarcopenia. Therefore, additional studies are essential to examine the effects of MOP intake and exercise intervention on the body composition and fitness of patients over a longer period.
PERBEDAAN KANDUNGAN E.coli DAGING AYAM DI PASAR TRADISIONAL KEPUTRAN SELATAN DAN PASAR SWALAYAN ‘X’ KOTA SURABAYA
Authors: Permana Athalla , W R. Bambang
Published: October 2021

Hygiene and sanitation practices in chicken influenced Eschericia coli bacterial contamination in food. A Study conducted by Sasmita and Juwita mentioned that there was positively E.coli content in chicken meat in supermarket. Thus, the purpose of this study was to assess the difference of E.Coli content in chicken meat and personal hygiene of food handler. It was an observational study with cross sectional approach. The population of this study included traditional market sellers and supermarkets. The sample of this study consisted of 14 samples of chicken meat in which 7 samples came from the South Keputran traditional market and other 7 samples came from Supermarket ‘X’. Moreover, 7 traditional market sellers and 2 supermarkets were involved to be examined. Variables of the study were E.coli content in chicken meat from Traditional Market of South Keputran and Supermarket ‘X’ and personal hygiene. Samples of chicken meat was done by accidental sampling. Data were collected through interview and observation, whereas the difference of E-Coli content was analyzed using statistical test. The results of this study indicated that one of chicken meat samples positively contained E.Coli bacteria, and no significant differences of the E.coli content were found on the chicken meat samples from both the Traditional Market of South Keputran and Supermarket ‘X’. The suggestion that can be given to Supermarket ‘X’ seller is to control and pay close attention to the sanitation process from suppliers to retails
PERBEDAAN EFEKTIFITAS FILM ANIMASI DAN FILM CERITA TERHADAP PENINGKATAN PENGETAHUAN DAN SIKAP ANAK TENTANG KESEHATAN GIGI
Authors: Sandya Isha , Widati Sri
Published: October 2021

According to Basic Health Research 2013 states that the age group less than 12 years ie age 5-9 years 28.9% suffered dental caries. The aim of this study is to analyze the effectiveness of animated movies and non- animated movies in improving children’s knowledge and behavior concerning dental health. This study was designed based on quasi experimental design. The samples of this study were the students of Class 3A and Class 3B SDN 03 Kepanjen consisting of 63 students. The independent variables of this study were animated movie and non-animated movie concerning dental health while the dependent variables were children’s knowledge and behavior. The collected data were analyzed using Mann Whitney test. The findings of this study show that the respondents are aged between 8 and 10 years old. There is difference in terms of knowledge before and after the students received intervention through animated movie and non-animated movie. Animated movie seems to be more effective in improving the respondents’ knowledge to maintain dental health than non-animated movie as indicated by the average score for animated movie intervention is higher than non-animated movie intervention.
PENGARUH MUTU LAYANAN TERHADAP KEPUASAN DI POLIKLINIK HAMIL INSTALASI RAWAT JALAN RUMAH SAKIT UMUM HAJI SURABAYA
Authors: Rahmaningtyas Rezky Intan , Supriyanto Stefanus
Published: October 2021

The number of patient revisits in maternity polyclinic of Surabaya Haji Public Hospital decreased within the period of 2015 – 2016 as much as 24%. In addition, there were several indicators complained by patients in the maternity polyclinic of Surabaya Haji Public Hospital. The purpose of this study was to analyze the effect of service quality to patients’ satisfaction and loyalty in the maternity polyclinic based on Donabedian Theory. It was an observational analytic study, and sampling was taken by simple random sampling technique which in the end obtained a total of 141 respondents. The results of the study indicated that service quality significantly affected patients’ satisfaction. The mean value <3.00 was an issue that should get attention from the polyclinic including structural components (the parking space which is not large and comfortable enough) as well as process components (waiting duration to get services from physicians). Thus, recommendation given to the polyclinic could be to conduct periodic evaluation of the application of service quality as well as patients’ satisfaction and reschedule physicians’ medical practices.
Pengaruh Ekstrak Daun Kecibeling (Strobilanthes crispa), Kayu Manis (Cinnamon), dan Kersen (Muntingia calabura) Terhadap Indeks Glikemik pada Pengolahan Beras Metode Pratanak
Authors: Margono Margono , Louise Louise , Choirudina Laila Zulhijah , Safitri Ameilia Ayu , Hanifah Fawnia
Published: October 2021

Diabetes mellitus is a top five deadly disease in Indonesia. A healthy diet with consuming low sugar index food is suggested to prevent diabetes mellitus. Rice as the main source of carbohydrate in Indonesia is categorized as food with a high glycemic index. This study is experimenting rice with a low glycemic index that suitable to be consumed by diabetes mellitus sufferer. Various extracts are used in the making of low glycemic index rice such as strobilanthes crispus, cinnamon, and muntingia calabura. The rice is marinated with 1% extract for 2 hours and continued to cook in an autoclave for 15 minutes with temperature 116°C. The rice then dried in an oven at 50°C for 24 hours before it cooked in a rice cooker and can be consumed. The result shows that strobilanthes crispus and cinnamon extract rice has lower glycemic index than common rice.
Konduktivitas Listrik Poly(Lactic Acid) dengan Variasi Bahan Isian Karbon: Review
Authors: Efendy Gabrella , Handayani Indah Dwi , Husni N Fauziatul , Habibah Siti , Kaavessina Mujtahid
Published: October 2021

Conductive Polymer Nanocomposites (CPC) merupakan material yang banyak digunakan sebagai sensor, sel fotovoltaik, kapasitor, dioda, dan perangkat energi yang sangat mudah meregang. CPC memiliki beberapa sifat unggul, diantaranya konduktivitas elektrik yang tinggi, ringan, tahan korosi, dan memiliki karakteristik mekanis yang bagus. Konduktivitas elektrik pada polimer diperoleh dan diatur dengan menambahkan bahan isian berbasis karbon seperti: Carbon Black (CB), Carbon Nano Tube (CNT), Graphite maupun Graphene. Metode panambahan bahan isian dapat dilakukan dengan Melt blending dan Solvent blending. Metode melt blending memiliki beberapa keunggulan, diantaranya mudah, praktis, murah, serta dapat diaplikasikan pada berbagai bahan. Selain itu, metode melt blending termasuk  ramah lingkungan karena tidak ada pelarut organik. Sedangkan kelebihan metode Solvent Blending adalah campuran yang lebih kuat dikarenakan disperse yang terjadi merata dan lebih baik. Pada review, penulis mengulas tentang sifat elektrik dari CPC berbasis poli asam laktat dan berbagai bahan isian  karbon, yaitu CNT, graphene, dan CB. Hasil studi literatur menunjukkan bahwa konduktivitas elektrik CPC meningkat seiring bertambahnya komposisi bahan isian. Pada metode solvent blending faktor yang berpengaruh adalah komposisi PLA dan filler, suhu operasi, kecepatan pengadukan, waktu pengadukan, dan solvent yang digunakan. Sedangkan metode melt blending faktor yang berpengaruh adalah komposisi PLA dan filler, suhu operasi, kecepatan, dan waktu.

 

Kata kunci: Poli Asam Laktat, CNT, CB, Graphene, CPC
Computer components for solving the problems of optimal control of the rolling stock of the railways of Ukraine
Authors: Dmitrienko Valerii , Mezentsev Mykola
Published: October 2021

The solution of the problems of optimal control of traction rolling stock, as a rule, is performed under the assumption that the external environment in relation to the composition remains unchanged and does not affect or weakly affects the laws of control. However, the actual movement of trains on the railway makes significant changes to the pre-calculated laws of control and schedules. In this regard, the article considers approaches to the control of the composition taking into account changes in the state of the environment. Such approaches require the identification of the external environment in the process of movement of a particular composition and the correction of control laws when changing the parameters of the external environment. In this case, there is a transition to proactive control.  Figs.: 1. Refs.: 16 titles.
Point placement method in the plane taking into account points mutual reachability
Authors: Dashkevych Andrii
Published: October 2021

The paper presents an approach for determining the positions of a set of points that provide a given ratio of mutual reachability for a given point set on the plane. The presented method consists in drawing circles with centers at given points of the set on a regular grid and determining the intersection points of the maximum number of circles. The proposed method is implemented in the form of a software tool that allows you to find the minimum required set of points on a regular grid, which covers a given set, and also allows you to visualize the results. Figs.: 3. Refs.: 13 titles.
Improving the web-based recommender system through collaborative filtering
Authors: Pokryshka Sergey , Shumova Larisa
Published: October 2021

The solution to the problem of improving the recommendation web-oriented system through the use of collaborative filtering to provide recommendations to users of the web service with articles on gaming topics is presented. In the course of the research, a set of stages of development and improvement of the recommendatory web-oriented system was systematized. The structure of the database and the method of collaborative filtering using the proposed similarity measure to form recommendations for users are presented. The preliminary structuring of articles by categories was used to identify user preferences and provide recommendations. The use of collaborative filtering with the proposed similarity measure allowed us to increase the number of articles viewed by users. Ill.: 2. Bibliography: 10 titles.
Community-led disaster resilience in Nauiyu Aboriginal community
Authors: Ingram Annie
Published: October 2021

There is a need for emergency management systems in Australia to shift to a more collaborative model that involves working with communities rather than simply delivering to communities. This research paper argues that in order to address this, emergency services organisations in Australia need to continue to shift from a service delivery approach to a more localised, participatory and consultative model that acknowledges and harnesses local leadership, knowledge, skills and experience creating opportunities for community driven and fit-for-purpose emergency management. The paper makes the case for why localised approaches are important in places with diverse populations such as the Northern Territory (NT). The NT Aboriginal community of Nauiyu’s experience of evacuations due to flooding in 2015 and 2018 will be used as a case study to offer an example of locally led approaches to disaster resilience.
Buoyancy Force on a Plain or Perforated Portion of a Pipe
Authors: Cayeux E. , Stokka S. , Dvergsnes E. W. , Thorogood J. L.
Published: October 2021

Torque and drag models have been used for several decades to calculate tension and torque profiles along drillstrings, casing strings, and liner strings. Buoyancy forces contribute to the loads acting on the pipe and affect its interaction with the borehole wall. Torque and drag calculations account for these localized effects, as well as the material internal forces, torques, and moments on each side of the contact. When the analysis is applied to a discrete length of pipe, the cross sections at each end do not contribute to the buoyancy forces because they are not in contact with the fluid, except where there is a change in diameter or at the end of the string of pipe.

We argue that it is important to check that the models used for solid pipe torque and drag calculations remain valid for sand screens, in particular, the extent to which the buoyancy forces acting on a perforated tube might differ from those on a solid pipe. Because the buoyancy force is the result of the pressure gradient acting on the surface of the pipe, the presence of holes may also influence the buoyancy force. We propose that there are theoretical differences between local buoyancy forces acting on plain or perforated tubes.

This paper describes how to calculate the local buoyancy force on a portion of a drillstem by the application of Gauss’ theorem and accounting for the necessary corrections arising from the cross sections not being exposed to the fluid. We built an experimental setup to verify that the tension inside a pipe subject to buoyancy behaves in accordance with the derived mathematical analysis. With complex well construction operations, for instance during extended-reach drilling or when drilling very shallow wells with high buildup rates, the slightest error in torques and drag calculations may end up jeopardizing the chances of success of the drilling operation. It is therefore important to check that the basis of design calculations remain valid in those contexts and that, for instance, sand screens or slotted liners may be run in hole safely after a successful drilling operation.
Age-Induced Aortic Modifications Are Accompanied By Alteration in the Antioxidant Defense System in Female Rats
Authors: Asad Sabahat Binte , Qian Xin , Wang Jiao , Gao Qiang , Cao Yang , Huang Yujia , Lu Chunmei , Zhu Hui
Published: October 2021

Aging causes significant structural and functional changes in the vasculature, disrupting homeostasis and affecting the cardiovascular system's performance. This study looked into the effects of aging on the aorta and how that affects antioxidant capability. As a result, healthy aging female SD rats (n=10) were compared to their younger counterparts. Blood pressure, serum lipid profile, aortic histology examination, and the expression of antioxidant enzymes were all assessed. When aged rats were compared to young rats, their blood pressure and serum lipid levels were dramatically different. Furthermore, histological examination of the aorta of aging rats revealed structural changes, characteristic apoptotic nuclear morphology, and the formation of fatty deposits. Different antioxidant enzyme’s protein expression was also studied. In aged rats, the expressions of SOD-1(superoxide dismutase), GSS(glutathione synthetase), NRF2(NF-E2-related factor 2), KEAP-1(Kelch-like ECH-associated protein 1), and HO-1(Heme oxygenase 1) were drastically changed. This study revealed that age-induced aortic changes are associated with an altered antioxidant system, according to this study.
Evaluation of Lymph Nodes Adequacy in Patients with Colorectal Cancer: Results from a Referral Center in Iran
Authors: Yahyazadeh Hossein , Mafi Ahmad Rezazadeh , Beheshti Marzieh , Ghareyazi Amin , Abdollahinejad Azita , Tahbaz Sahel Valadan
Published: October 2021

Background
the presence of lymph node metastases is one of the most important prognostic factors for long-term survival of patients with colorectal cancer. So, thorough pathologic examination of at least 12 lymph nodes is essential for accurate staging this disease, as well as choosing the best adjuvant treatment. The aim of this study is to assess the adequacy of lymph node harvest in patients with colorectal cancer.
Methods
This observational cross-sectional study was performed on 584 patients with colorectal adenocarcinoma who had undergone surgery from 2012 to 2017. Thereafter, the relevant demographic, pathological, and surgical data were extracted from the patients’ medical records and a relationship between the number of evaluated lymph nodes and other variables was also assessed.
Results
Among 584 studies cases in this study, 336 (57.5%) subjects had less than 12 evaluated lymph nodes. Mean and median number of the evaluated lymph nodes were calculated as 10.7 (± 5.6) and 10, respectively. The patients aged 60 years old and older and the cases with tumors located in descending colon and rectum were observed to have higher chances of inadequate lymph node retrieval. After an average follow-up for a 60-month period, 63% of the patients were alive. In the patients for whom less than 12 lymph nodes had been assessed, the median survival was estimated as 48 months. As well, in the patients for whom the number of the evaluated lymph nodes was ≥ 12, median survival was calculated as 54 months.
Conclusion
The number of the evaluated lymph nodes in our study was less than the standard number in more than half of the patients. Among various factors, older age, and tumor location in descending colon and rectum are found to be associated with sub-optimal assessment of lymph nodes. The number of lymph nodes dissected is also associated with survival.
Refractive And Ocular Indices In Kindergarten Israeli Children
Authors: Bahir Daniel , Raj Rhody David , Zion Itay Ben
Published: October 2021

Purpose: To report normative data on paediatric refractive and ocular indices in kindergarten Israeli children. Methods: Retrospective cross-sectional study of 101,417 Israeli children from 4-5 years old, obtained from 2013-2018. Data was collected using the PlusoptiX S12. We studied the number of referrals made for hyperopia, myopia, astigmatism and anisometropia. Results: Mean sphere value was 0.83D±0.73 for the right eye and 0.85D±0.73 for the left eye. Mean SE was 0.56D±0.66 for the right eye and 0.59D±0.67 for the left eye. Mean cylinder value was -0.53D±0.48 for the right eye and was the same, -0.53D±0.47, for the left eye. Mean axis values for the right and left eyes were 80.85°±55.57 and 80.42°±56.60 respectively. Mean pupil size was 5.83mm±0.87 for the right eye, and 5.82mm±0.88 for the left eye. 13.26% had anisocoria ≥0.4mm; of these, 0.66% had anisocoria >1.0mm. There was no difference in pupil size between sexes or different cities. Mean IPD was 49.58mm±3.50, and mean gaze vector value was 2.64±1.66. According to the Vision Screening Guidelines, 0.8% of children had hyperopia and 0.17% had myopia. 6.22% of children had astigmatism and 10.85% had anisometropia. ﻿Conclusion: Amblyopia is the most common cause of unilateral vision loss in childhood. The earlier the diagnosis, the better the outcome, hence the importance of investigating the causative indices leading to amblyopia in kindergarten. After searching the literature, this is the largest study population for this topic to our knowledge.
Erythrocyte Micronucleus Cytome Assay in Passer Domesticus and Environmental Remote Sensing for Inferring the Quality of Wild, Rural and Urban Areas
Authors: Mendez Sofia Elena , Quero Arnoldo Ángel Martín , Gorla Nora Bibiana María
Published: October 2021

The study of biomarkers in free-living birds can help indicate the degree of contamination in distinct environments. In addition, these environments can be characterized through the information provided by satellite images. The objectives of the present study were to analyze the types and quantity of cytogenetic biomarkers in Passer domesticus (sparrow) from three different environments; wild, rural and urban; and to analyze them in the context of land use and anthropogenic actions. Five thousand erythrocytes per bird were analyzed for the following nuclear alterations (NA): micronuclei (MN), nuclear buds, notched nuclei, binucleated cells, nucleoplasmic bridges, nuclear tails, peripheral nuclei and enucleated cells. In the study, wild birds exhibited five types of NA, seven types were found in rural birds; and all types were encountered in urban birds. The only NA that exceeded a frequency of 2 NA/ 1000 erythrocytes were peripheral nuclei in birds from the rural and urban sites, the latter environment characterized by 87% urban soil and air pollution. The highest frequencies of MN, peripheral nuclei and enucleated erythrocytes were recorded in sparrows from the rural site (p≤0.05). This area had been sprayed with chlorpyrifos 48%, the most widely used organophosphate in the region. Sparrows from the wild site, made up of 100% native forest, had higher frequencies of notched nuclei (p≤0.05). A precedent is set for the use of environmental remote sensing in a complementary manner with cytogenetic biomarker studies in birds for a joint analysis in environmental assessment.
Transcriptome Analysis of Ophiocordyceps Sinensis Under Low-Temperature Treatment
Authors: Xie Fang , Su QiangJun , He Li , Uwitugabiye Vestine , Xia Yingxia , Zhou Gang , Chen Zhaohe
Published: October 2021

This study aims to investigate the effect of low temperature on the gene expression in Ophiocordyceps Sinensis. To set up the experiments, two groups of Ophiocordyceps Sinensis were grown at 4°C and 18°C, respectively, for 60 days. Differential gene expression was analyzed by transcriptome sequencing and the morphology of mycelium was studied under scanning electron microscope for the two groups. The results showed that there were significant differences in hypha morphology between the two groups. Transcriptome analysis indicated that 2799 genes were differentially expressed in the low-temperature treatment group compared to the normal temperature group. Among these genes, 1489 were up-regulated, whereas 1310 were down-regulated. Further analysis revealed that 33 genes were only expressed at low temperature compared to 26 genes which were only expressed at normal temperature. GO enrichment analysis showed that the 33 genes were related to redox enzymes, which have functions in clearing reactive oxygen species and free radicals caused by low-temperature environment. KEGG enrichment analysis showed that the 33 genes were mainly involved in the cyanoamino acid metabolism, biosynthesis of amino acids, carbon metabolism, pantothenate and CoA biosynthesis, biotin metabolism, phenylpropanoid biosynthesis, apoptosis and other metabolic pathways. Our observations provide fundamental clues on the relationship between the low-temperature stimulation and the fruiting body development and further promote the research progress on Ophiocordyceps Sinensis.
Comparison of multi-axis printing strategies effects on large-scale 3D printed surface quality
Authors: Krčma Martin , Paloušek David
Published: October 2021

The purpose of this study is to determine impact of several multi-axis 3D printing strategies on buildability, surface quality, accuracy and strength of large scale single-walled object (printed in a so called vase mode). To achieve this goal, test objects were printed using four distinct printing strategies by an industrial robotic arm and a pellet-fed screw extruder. The strategies tested in this study are: regular 3-axis deposition with planar layers, 5-axis deposition with planar layers, 3-axis deposition with non-planar layers, and 5-axis deposition with non-planar layers. Custom scripts for nonplanar slicing and for tilt control during multi-axis printing were developed to achieve these prints and are explained in this study. The results were evaluated using 3D scanning and mechanical testing, and surface accuracy, surface roughness and layer adhesion strength were compared. The most important findings are: 1. 5-axis motion alone does not improve the results of the printing, 2. While nonplanar printing can improve surface quality its usability is geometry dependent, 3. Multi-axis nonplanar printing, even with partial tilt (30°) can expand printability with enhanced quality to at least 75° overhang angle. Future potential of these methods and requirements to achieve them is discussed.
Absolute Eosinophil Count May be an Optimal Peripheral Blood Marker to Identify Risk of Immune-Related Adverse Events in Advanced Malignant Tumors Treated with PD-1/PD-L1 Inhibitors: A Retrospective Analysis.
Authors: Ma Yan , Ma Xiao , Wang Jingting , Wu Shanshan , Wang Jing , Cao Bangwei
Published: October 2021

Background

This study aimed to investigate the predictive values of serum biomarkers including absolute eosinophil count (AEC), neutrophil–lymphocyte ratio (NLR), and platelet–lymphocyte ratio (PLR) with respect to immune-related adverse events (irAEs) during anti-PD-1/PD-L1 inhibitor treatment in patients with advanced malignant tumors.
Methods

We retrospectively analyzed 95 patients with advanced cancer who were treated with anti-PD-1/PD-L1 inhibitors from January 1, 2017 to May 1, 2020, in our cancer center. We then analyzed associations between irAEs and anti-PD-1/PD-L1 inhibitor responses and evaluated the predictive values of serum biomarkers with respect to risk of irAEs.
Results

The incidence of irAEs was 55.8%. There were no statistically significant differences between the irAEs and no-irAEs groups in objective response rate (ORR) or disease control rate (DCR). However, landmark analysis showed that the irAEs group had better survival after 120 days following the initiation of anti-PD-1/PD-L1 inhibitor treatment, compared with the no-irAEs group. The incidences of irAEs were greater in the high-AEC and low-NLR groups than in the low-AEC and high-NLR groups. Univariate logistic analysis showed that low NLR, ECOG performance status (0–1), and high AEC were risk factors for irAEs. Multivariate logistic analysis showed that high AEC and good ECOG performance status were independent predictors for irAEs.
Conclusions

irAEs may be associated with a survival benefit. Baseline AEC is a strong predictor of irAEs in patients undergoing treatment with anti-PD-1/PD-L1 inhibitors.
The Diversity and Heterogeneity of TCR and BCR in Pan-Cancer
Authors: Li Bo , Zhang Jing , Guo Jin-dan , TANG Hui-xue , Hu Wen-xiang , XU Li-da , Chen Yu-bao
Published: October 2021

Background: With the development of the sequencing technology, RNA-seq is becoming more and more popular. The method of using RNA-seq technology to analyze the immune repertoire has the advantages of low sample demand, simple operation, and comprehensive information.Result: The RNA-seq data from public database were used to analyze and compare the TCR and BCR sequences of cancer and normal tissues in four types of cancers, including colon adenocarcinoma, lung adenocarcinoma, pancreatic adenocarcinoma and stomach adenocarcinoma. It was found that the clonal diversity of TCR among various types of cancer is different, and the variety of BCR between cancer tissues and healthy tissues is obvious. Based on the analysis of non-shared CDR3 sequences, the degree of the heterogeneity of TRB is: different cancer types> different individuals with same cancer> cancer tissues and paracancerous tissues of the same individual. Also, the correlation between the expression levels of the five main immune checkpoints genes and the count of TCR clones displayed various among different types of cancers.Conclusion: The results verify the advantage of RNA-seq analyzing in acquiring individual immune repertoire. Moreover, the heterogeneity of TCR in different cancers and the diversity of BCR in tumour and adjacent tissues shown in the results, provide hints at developing the strategies of tumour immunotherapy.
Operando electrochemical spectroscopic ellipsometry: Insights into electrochemical behavior of catalyst materials under realistic working conditions
Authors: Sachse René , Sahre Mario , Bernicke Michael , Bernsmeier Denis , Hodoroaba Vasile-Dan , Strasser Peter , Kraehnert Ralph , Hertwig Andreas
Published: October 2021

Large-scale hydrogen production using proton exchange membrane water electrolysis (PEM-EL) requires a drastic reduction in the current noble metal content of the electrodes. To achieve this, new analytical techniques for characterizing solid-liquid catalytic interfaces, applicable in operando under a variety of realistic operating conditions, are critical because they provide a deeper understanding of the relationships between catalyst state, structure, and catalytic performance. However, many analytical techniques cannot be applied in liquid environments at realistic potentials and current densities. We propose electrochemical spectroscopic ellipsometric analysis (ECSE), performed in realistic electrolysis cells, as a new analytical operando method for characterizing electrochemical reactions at solid-liquid interfaces under widely varying working conditions. The method is first validated on a platinum surface using ex-situ and operando ellipsometric analyses. Subsequently, the physico-chemistry of a mesoporous IrOx catalyst film under oxygen evolution reaction (OER) potentials was investigated, showing precise reversible and irreversible potential-dependent variations of a number of physical material properties relevant to catalysis.