bluuebunny/crossref_metadata_2025 huggingface dataset:
Connect Resound: Using online technology to deliver music education to remote communities
Authors: King Andrew , Prior Helen , Waddington-Jones Caroline
Published: March 2020

This article describes an action research project that aimed to widen participation for music education in schools in England (United Kingdom). The Connect Resound project involved a pilot stage in North Yorkshire (England, United Kingdom) followed by a roll-out to four further geographical regions of England: Cumbria; Durham/Darlington; East Riding of Yorkshire; and Cornwall. The project involved testing a technological framework created to bring music education to schools with little or no music instrumental lessons within primary schools at key stage 2 (pupils aged 7–11 years). The pilot and roll-out phases refined the approach and established a business case for a grant to roll out the project nationally in 2017. The approach used in the study provided not only the instrumental lessons but also continuing professional development for teachers, on-demand technical support, and access to music performances and masterclasses. The research team designed and tested several scenarios for using technology in this environment some of which were using single cameras and others that used a multi-camera set-up. One of the approaches used technology to allow the teachers and pupils access to different camera angles and high-quality audio to deliver the lessons which proved beneficial. The project team captured both video data as well as interviews and questionnaires with participants in order to better understand and refine the approach developed. This article reports upon the challenges and opportunities provided by the project in terms of the technology and environment, an evaluation using a case study approach of how the teachers used the technology, and feedback in the form of questionnaires from pupils and parents/carers concerning the lessons. Issues around the technology concerned time lag, initial technical problems, and background noise in the teaching environment amplified by the technology. The different camera angles adopted in the project proved valuable for teachers, potential issues with assembling and tuning instruments were considered, and beginner technique could be demonstrated using this approach.
GRAPHITE FURNACE ATOMIC ABSORPTION SPECTROPHOTOMETRY SEBAGAI METODE ANALISIS LOGAM BERAT
Authors: Budiyanto Fitri
Published: March 2020

GRAPHITE FURNACE ATOMIC ABSORPTION SPECTROPHOTOMETRY AS A METHOD FOR ANALYZING HEAVY METAL. Heavy metal, mostly present in a (ultra) trace-level, becomes one of the hazardous pollutants due to its toxicity, bioaccumulative, biomagnification characters. Conducting a micro analysis of these trace-level pollutants, a sensitive instrument and method are strongly recommended. Graphite Furnace Atomic Absorption Spectrophotometer (GFAAS) offers a solution for the challenge. It uses the principle of light emission absorption by nascent atom cloud from the metals. The analysis has been developed in three stages of the tube heating programs, i.e. drying, ashing and then atomizing element at 3000° C. Since the injected sample is almost completely atomized, the sensitivity of GFAAS is extremely high and this value is covering up the disadvantages of the other analyses. Therefore, the GFAAS analysis is suitable fo ultra-trace analysis of ultra-trace pollutants like heavy metals in environment.
PENGENALAN CITRA SATELIT SENTINEL-2 UNTUK PEMETAAN KELAUTAN
Authors: Oktaviani Nadya , Kusuma Hollanda A
Published: March 2020

RECOGNITION AND UTILIZATION OF SATELLITE IMAGE SENTINEL-2 FOR MARINE MAPPING. Sentinel-2 is a satellite launched by a collaboration between The European Commission and the European Space Agency in the Global Monitoring for Environment and Security (GMES) program. The satellite has a mission to scan the Earth’s surface simultaneously at an angle of 180 each satellite with a 5-day temporal resolution with the same appearance on the equator and has a spatial resolution of 10 m, 20 m, and 60 m. There are 13 multispectral channels including VNIR and SWIR. Four channels with 10 m spatial resolution adapt with SPOT 4/5 and user’s comply requirements for land cover classification. Six channels with 20 m spatial resolution becomes a requirement for other Level 2 processing parameters. Channels with 60 m spatial resolution are specified for atmospheric correction and cloud filtering (443 nm for aerosols, 940 nm for moisture, and 1375 for thin cloud detection). Based on these specifications, Sentinel-2 can be an alternative for users to obtain image data with spatial, temporal, radiometric, and spectral resolution is better than SPOT and Landsat. Sentinel-2 can be downloaded for free and easy by the general public. The existence of image by Sentinel-2 is expected to be used optimally, especially for remote sensing analysis in marine field.
KARAKTERISTIK DAN DAMPAK MAKROALGA INTRODUKSI
Authors: Handayani Tri
Published: March 2020

CHARACTERISTIC AND IMPACTS OF INTRODUCED MACROALGAE.  An introduced macroalgae is species of macroalgae that have been introduced beyond its native range through human activities and has become successfully established in the new locale. Introduced macroalgae have an impact on ecology and evolution, i.e. direct and indirect competitions with native biota (space monopolization and change in community composition), effects on higher trophic levels (herbivores, associated fauna, toxicity), habitat change (changed structure, sediment accumulation), change of ecosystem processes (alteration of trophic structure) and genetic effects. Introduced macroalgae also have an impact on economy and social, i.e. costs of loss of ecosystem functions or values, impacts on environmental amenity, impacts on human health, management costs (government/non-government), costs of research into introduced species, costs for eradication and control measures and costs for education/extension campaigns. Management of impact and research are needed to minimize the impact of introduced macroalgae.
MENGENAL PEREKAYASA EKOSISTEM
Authors: Cintra Allsay Kitsash Addifisyukha
Published: March 2020

UNDERSTANDING THE ECOSYSTEM ENGINEERS. Ecosystem engineers are organisms that can create, destroy or even maintain the sustainability of a particular habitat. The process of ecosystem engineering begins with structural changes in the environment and subsequently change the abiotic the biotic term or the existence of other organisms. Ecosystem engineers are divided into two, namely autogenic and allogenic engineers. Autogenic engineers change the habitat condition by shifting their body conditions, whereas allogenic engineers that can directly change habitat conditions. The impact of ecosystem engineers on the environment is determined by the magnitude and duration of structural changes made or abandoned by the ecosystem engineer. Understanding the concept of ecosystem engineering is useful as one of the efforts to restore habitat and conservation acts.
Reconstruction of Thumb Polydactily: A Case Report
Authors: Budiman Budiman , Utami Gladya , Nazwan Sani T. Fadli
Published: March 2020

Background: Polydactyly is the most common hand congenital abnormality found, next after syndactyly. The presence of these extra fingers is not merely duplication but is accompanied by abnormal hypoplastic structures, abnormal joints, tendon anomalies, and anomly of the insertion of ligaments. There are many tehniques proposed to reconstruct polydactyly, from simple excision of bones, ligaments, and tendons to complex reconstructions. We report a case of polydactily, the patient had bone exicision of the duplicates when the patient was four-month-old, but that extra metacarpal with no phalanges resulted in a greater space of finger 1 and 2.

Patient and Method: A 21-year-old woman complaining of difficulty in grasping because the space between first and second fingers is too far away, and the extra metacarpal bone is protruding that causes snagging and stumbling on other objects. She had a history of surgical removal of polydactyl when she was 4-month-old. The patient has a limitation in hand activities.

Result: Six months after surgery, the patient was satisfied with the results. The fingers has better mobility, good appearance. No more prominent bone, and neuropathic problems, or other disorders were found.

Conclusion: Polydactyly is a common congenital hand occurrence. Understanding the anatomy to guide the reconstructive actions is important. It is not only about which digit would be preserved, but we have to concern about what our patient need, improving the quality,  patient's hand function, and the aesthetic aspect.
Drawing a Structural Model by the Most Effective Components on Optimal Global Marketing
Authors: Nazari Farzad , Najafi Soodabeh , Shahsavari Farnaz , Zeynalzadeh Aylar
Published: March 2020

Goal: International trade and success in this field is one of the most important goals based on the profitability and reputation among different companies and organizations, in which the most important tool is optimal global and international marketing; therefore, this research aims at drawing the model of structure by the components influencing optimal global marketing.

Design / Methodology / Approach: To this end, 385 experts, professionals, and scholars in this field, whose number was determined by the Cochran formula, completed a researcher-made questionnaire. In this paper used the structural equation method.

Results: The results show that the application of technology, product quality, price, variety and communication (brand) are the five affecting factors on optimal global marketing. In the meantime, the product quality has the greatest effect on optimal global marketing, and with exception of the diversity which is the indirect predictor of optimal global marketing, other variables directly predict this indicator, as well as the results of fitting the model showed that the created model is an efficient and reliable tool for investigating the components affecting the identification of global optimal marketing.

Practical implications: results of this study can be use to increase sales and supply rates of products Because by knowing the best marketing agents can increased the rate of supply of goods and products.

Research limitations: This research has been done in Iran, Naturally, it has to be validated for use elsewhere in the world, it is possible that it may not be cited elsewhere or give different results.

Originality / Value: It has not been studied so far and the results of this article can be used all over the world.
Remarks on Ovid and the Golden Age of Augustus
Authors: Łukaszewicz Adam
Published: March 2020

Publius Ovidius Naso was an outstanding poet of the Augustan age who after a period of successful activity was suddenly sent to exile without a formal judicial procedure. Ovid wrote frivolous poems but inserted into his works also the obligatory praises of Augustus. The standard explanation of his relegation to Tomis is the licentious content of his Ars Amatoria, which were believed to offend the moral principles of Augustus. However, the Ars had been published several years before the exile. The poet himself in his Pontic writings mentions an unspecified error and a carmen, pointing also to the Ars, without, however, a clear explanation of the reason for his fall. The writer of the present contribution assumes that the actual reason for the relegation of the poet without a trial were the verses of his Metamorphoses and especially the passage about the wicked stepmothers preparing poison. That could offend Livia who, according to gossip, used poison to get rid of unwanted family members. Ovid was exiled, but the matter was too delicate for a public justification of the banishment. When writing ex Ponto the poet could not explicitly refer to the actual cause of his exile.
Die Erkennung unangemessener Inhalte im Internet: KI-Verfahren, Evaluierung und Herausforderungen
Authors: Mandl Thomas
Published: March 2020

In sozialen Medien finden sich sehr oft aggressive und hasserfüllte Posts. Deren automatische Erkennung ist wünschenswert und wird derzeit intensiv erforscht. Die Qualität der entsprechenden Algorithmen muss laufend bewertet werden. Der Artikel berichtet von Evaluierungsergebnissen und den Herausforderungen im Rahmen der HASOC Initiative 2019. Davor werden die neuronale Netzwerk-Architekturen wie beispielsweise BERT eingeführt, die derzeit die besten Ergebnisse liefern.
Traceability validation of six enzyme measurements on the Abbott Alinity c analytical system
Authors: Aloisio Elena , Frusciante Erika , Pasqualetti Sara , Infusino Ilenia , Krintus Magdalena , Sypniewska Grazyna , Panteghini Mauro
Published: March 2020

Background

Laboratory professionals should independently verify the correct implementation of metrological traceability of commercial measuring systems and determine if their performance is fit for purpose. We evaluated the trueness, uncertainty of measurements, and transferability of six clinically important enzyme measurements (alanine aminotransferase [ALT], alkaline phosphatase [ALP], aspartate aminotransferase [AST], creatine kinase [CK], γ-glutamyltransferase [γGT], and lactate dehydrogenase [LDH]) performed on the Abbott Alinity c analytical system.

Methods

Target values and associated uncertainties were assigned to three pools for each enzyme by using the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) reference measurement procedures (RMPs) and the pools were then measured on the Alinity system. Bias estimation and regression studies were performed, and the uncertainty associated with Alinity measurements was also estimated, using analytical performance specifications (APS) derived from biological variability of measurands as goals. Finally, to validate the transferability of the obtained results, a comparison study between two Alinity systems located in Milan, Italy, and Bydgoszcz, Poland, was carried out.

Results

Correct implementation of traceability to the IFCC RMPs and acceptable measurement uncertainty fulfilling desirable (ALP, AST, LDH) or optimal APS (ALT, CK, γGT) was verified for all evaluated enzymes. An optimal alignment between the two Alinity systems located in Milan and Bydgoszcz was also found for all enzyme measurements.

Conclusions

We confirmed that measurements of ALT, ALP, AST, CK, γGT, and LDH performed on the Alinity c analytical system are correctly standardized to the IFCC reference measurement systems and the system alignment is consistent between different platforms.
Mortalität bei Hitzeextremen in Deutschland
Authors: Uphoff Helmut , Larem Andreas , Becker Laura , Piro Ann-Kathrin , an der Heiden Matthias
Published: March 2020

In Deutschland werden bei zunehmender Häufigkeit von Hitzewellen bundesweit von 2001 bis 2015 fünf Sommer mit signifikanter hitzebedingter Steigerung der Mortalität erkennbar. Dabei sind insgesamt zwischen 16.000 und 37.000 zusätzliche Todesfälle durch das Robert Koch-Institut (RKI) geschätzt worden. Für Hessen wurden 2000 bis 2019 sechs Sommer mit insgesamt zwischen 1.500 bis 4.000 zusätzlichen Todesfällen geschätzt. Eine zeitnahe tagesgenaue Erfassung der Gesamtmortalität unterstützt die Fokussierung der Hitzeschutzmaßnahmen und fördert die Aufmerksamkeit und das Interesse der Medien.
Klimawandel und Gesundheit: Aktivitäten in Bayern
Authors: Kutzora Susanne , Weilnhammer Veronika , Heigl Katharina , Korbely Christine , Herr Caroline , Heinze Stefanie
Published: March 2020

Zur Anpassung an den Klimawandel werden in Bayern mehrere Projekte durchgeführt, die sich auf unterschiedliche klimawandelbedingte Gesundheitsherausforderungen fokussieren. Im Folgenden werden drei Projekte des Bayerischen Landesamts für Gesundheit und Lebensmittelsicherheit (LGL) zu diesem Thema vorgestellt: das Verbundprojekt „Klimawandel und Gesundheit“, das Projekt „Klimaanpassung in der Pflege“ und „ePIN – Polleninformationsnetzwerk in Bayern“.
Hitzeschutzplan Steiermark/Österreich – Klimawandelanpassung in der Praxis
Authors: Pollhammer Christian
Published: March 2020

Aufgrund des Klimawandels und den damit einhergehenden Herausforderungen für den öffentlichen Gesundheitsdienst wurde 2011 der Steirische Hitzeschutzplan (HSPL) vorgestellt und als operatives Maßnahmenbündel ein Hitzewarnsystem (HWS) installiert. Im Herbst 2017 wurde das HWS mittels einer Online-Umfrage evaluiert. Die Ausgestaltung eines solchen Informationssystems in der Praxis wie auch die Aufbereitung von zielgruppenrelevanten Informationen sind maßgeblich für die Effektivität und Akzeptanz von derartigen Warnsystemen.
Klimawandel und Auswirkungen auf die menschliche Gesundheit
Authors: Augustin Jobst
Published: March 2020

Klimatische Veränderungen haben mit hoher Wahrscheinlichkeit einen Einfluss auf die menschliche Gesundheit. Studien zeigen bereits die Auswirkungen, die zukünftig vermutlich noch an Relevanz gewinnen werden. Multikausale Zusammenhänge erschweren aber detaillierte Aussagen zu den künftigen Auswirkungen klimatischer Veränderungen auf die Gesundheit. Trotz Unsicherheiten kommt den Anpassungsmaßnahmen zur Reduzierung der Folgen des Klimawandels auf Morbidität und Mortalität eine hohe Bedeutung zu.
Hitzewellen und Klimawandel: Eine Herausforderung für Gesundheitsberufe
Authors: Schoierer Julia , Wershofen Birgit , Böse-O’Reilly Stephan , Mertes Hanna
Published: March 2020

Aufgrund des Klimawandels lässt sich in Deutschland bereits eine (spürbare) Steigerung von Anzahl, Dauer und Intensität von Hitzeperioden beobachten, mit Auswirkungen auf die menschliche Gesundheit, insbesondere älterer und pflegebedürftiger Personen. Das Klinikum der Universität München entwickelt Anpassungsstrategien an den Klimawandel zum Schutz der Gesundheit und in diesem Rahmen Bildungsmodule für Gesundheitsberufe sowie einen Hitzemaßnahmenplan für vollstationäre Einrichtungen der Altenpflege.
Gesundheitswesen und Klimaschutzpolitik: Synergien für eine gesunde und nachhaltige Gesellschaft
Authors: Eichinger Michael , Herrmann Martin
Published: March 2020

Die Überwindung der Klimakrise ist zur Schlüsselfrage für ein gesundes Leben im 21. Jahrhundert geworden. Um Synergien zwischen Gesundheitswesen und Klimaschutzpolitik zu heben, muss die Klimakrise als zentrales Querschnittsthema im Gesundheitswesen verankert werden. Zudem bedarf es der Stärkung von Lehre und Forschung, die unmittelbar zur Großen Transformation, d.h. zu einer raschen und umfassenden Neuausrichtung unserer Lebens- und Wirtschaftsweise auf Nachhaltigkeit, beitragen.
Hitze in der Stadt – Mikroklima und Anpassungsmaßnahmen: ein Fallbeispiel aus Freiburg
Authors: Matzarakis Andreas , Fröhlich Dominik
Published: March 2020

In der Stadt Freiburg im Breisgau im südlichen Oberrheingraben gab es um die Neugestaltung eines städtischen Platzes (Platz der Alten Synagoge) große Diskussionen. Im Vorfeld der Umgestaltung sollte mit Hilfe von Modellen die Auswirkung des Umbaus auf die in den Sommermonaten auf dem Platz ggf. auftretende Hitzebelastung für Menschen untersucht und quantifiziert werden. Die Ergebnisse der Untersuchung zeigen, wie man in Zeiten des Klimawandels Anpassungsmaßnahmen durchführen sollte.
Klimawandel und Gesundheit: Neue Herausforderungen für Public Health
Authors: Böckmann Melanie , Hornberg Claudia
Published: March 2020

Public Health hat vielfältige Möglichkeiten, gesundheitlichen Folgen des Klimawandels proaktiv zu begegnen. Neben Forschung zu Auswirkungen klimatischer Veränderungen, Nebeneffekten von Klimaschutz- und zur Wirksamkeit von Anpassungsmaßnahmen kommt Public Health-Expert*innen eine bedeutende Rolle in Prävention und Behandlung von klimawandelbedingten Gesundheitsstörungen zu. Erforderliches Wissen gilt es in Public Health- und Medizin-Curricula zu vermitteln. Weitere Aufgaben sind systematische Reduktionen von CO2-Emissionen im Gesundheitssektor und Umsetzung von Klimaanpassungsmaßnahmen.
METHOD OF THE SENSOR NETWORK RESOURCES ALLOCATION IN THECONDITIONS OF EDGE COMPUTING
Authors: Antoshchuk Svitlana G. , Lobachev Ivan M. , Maleryk Roman P.
Published: March 2020

The article describes the developed methodology, which allows to reduce the resource usage of the wireless sensor network by reducing the cost of sending data using a special routing table. The simulator was developed that allows you to explore and compare the use of routing table and random routing. The analysis of the data showed the advantages of using the established methodology, which can be applied to any networks that use edge computing and have intelligent data processing.
ARCHITECTURAL OBJECTS RECOGNITION TECHNIQUE IN AUGMENTED REALITY TECHNOLOGIES BASED ON CREATING A SPECIALIZED MARKERS BASE
Authors: Arsirii Olena  A. , Troianovska Yuliia L. , Prykhodko Iryna A. , Kotova Diana Yu.
Published: March 2020

The paper proposes a method for recognizing architectural objects when creating augmented reality mobile applications based on building a database of specialized markers. The main method of augmented reality technology for the recognition of architectural objects was chosen - the technology based on special markers. The range of pattern recognition algorithms suitable for the task is highlighted. These are algorithms based on the selection of key points of images and their descriptors. The most important aim is the stable recognition of architectural objects upon mobile applications for augmented reality-type digital guide creation based on specialized markers. The scientific basis of the research is a systematic approach in the analysis of the considered markers recognition algorithms, machine learning for the development of a database of marker images and AO recognition are used. The technique consists of the following steps: processing images of architectural objects with the aim of identifying key points, obtaining descriptions of selected control points as descriptors, creating AR-metadata that correspond to architectural objects, organizing joint storage in the local database of descriptors and their corresponding metadata, visualizing the architectural object and AR metadata. To implement the stages of processing images of architectural objects and obtain descriptors of key points, algorithms for extracting key points on images, such as SIFT, MSER, SURF, RIFF, RF, are analyzed. It is shown that these algorithms are invariant to scaling, rotation, as well as resistant to changes in light, noise and viewing angle. A comprehensive use of them for processing architectural objects with the aim of obtaining descriptors of reference points was proposed. To ensure stable recognition of AO according to the developed methodology based on machine learning for processing architectural objects with the aim of obtaining descriptors of key points, it was proposed to create an additional module using an ordered stack. The launch sequence and the number of algorithms can be changed.
Impact of age, body weight and metabolic risk factors on steroid reference intervals in men
Authors: Mezzullo Marco , Di Dalmazi Guido , Fazzini Alessia , Baccini Margherita , Repaci Andrea , Gambineri Alessandra , Vicennati Valentina , Pelusi Carla , Pagotto Uberto , Fanelli Flaminia
Published: March 2020

Objective

To evaluate the independent impact of age, obesity and metabolic risk factors on 13 circulating steroid levels; to generate reference intervals for adult men.

Design

Cross-sectional study.

Methods

Three hundred and fifteen adults, drug-free and apparently healthy men underwent clinical and biochemical evaluation. Thirteen steroids were measured by LC-MS/MS and compared among men with increasing BMI. Moreover, the independent impact of age, BMI and metabolic parameters on steroid levels was estimated. Upper and lower reference limits were generated in steroid-specific reference sub-cohorts and compared with dysmetabolic sub-cohorts.

Results

We observed lower steroid precursors and testosterone and increase in estrone levels in men with higher BMI ranges. By multivariate analysis, 17-hydroxyprogesterone and dihydrotestosterone decreased with BMI, while cortisol decreased with waist circumference. Estrone increased with BMI and systolic blood pressure. Testosterone decreased with worsening insulin resistance. 17-hydroxypregnenolone and corticosterone decreased with increasing total/HDL-cholesterol ratio. Age-related reference intervals were estimated for 17-hydroxypregnenolone, DHEA, 17-hydroxyprogesterone, corticosterone, 11-deoxycortisol, cortisol and androstenedione, while age-independent reference intervals were estimated for progesterone, 11-deoxycorticosterone, testosterone, dihydrotestosterone, estrone and estradiol. Testosterone lower limit was 2.29 nmol/L lower (P = 0.007) in insulin resistant vs insulin sensitive men. Furthermore, the upper limits for dihydrotestosterone (−0.34 nmol/L, P = 0.045), cortisol (−87 nmol/L, P = 0.045–0.002) and corticosterone (−10.1 nmol/L, P = 0.048–0.016) were lower in overweight/obese, in abdominal obese and in dyslipidaemic subjects compared to reference sub-cohorts, respectively.

Conclusions

Obesity and mild unmedicated metabolic risk factors alter the circulating steroid profile and bias the estimation of reference limits for testosterone, dihydrotestosterone, cortisol and corticosterone. Applying age-dependent reference intervals is mandatory for steroid precursors and corticosteroids.
Coagulopathy in the Acute Phase of Traumatic Brain Injury
Authors: Baranich A. I. , Sychev A. A. , Savin I. A. , Polupan A. A. , Oshorov A. V. , Potapov A. A.
Published: March 2020

Acute traumatic brain injury (TBI) can be accompanied by coagulopathy. In TBI, when an increased risk of hemorrhagic lesions in the brain tissue exists, keeping the normal hemostasis is crucial.

The aim: to determine the incidence of coagulopathy in the acute phase of isolated TBI and identify the correlation between the types of hemostasis disorders and the severity of TBI.

Materials and methods. We analyzed 323 case records of patients with TBI hospitalized to the Neurosurgery Center ICU from 2008 to 2016, 118 of them were included in the study. Criteria for inclusion were acute isolated TBI, hospitalization in the ﬁrst 72 hours after injury, young and middle-aged patients. On admission to the hospital, all patients were assessed according to the Glasgow Coma Scale (GCS) and divided into two groups: group I with severe TBI, group 2 with mild and moderate TBI. All patients underwent blood coagulation testing (APTT, PTI, ﬁbrinogen concentration, platelet count).

Results. In 63.6% of patients with acute TBI coagulopathy were found, most of them (55.1%) had hypocoagulability state and were observed in the group of severe PMT (62.5%). The most frequent signs of coagulopathy were reduced PTI of less than 70% and thrombocytopenia of less than 150×109/l. A weak correlation (R=0.276; P=0.002) was found between the development of thrombocytopenia and adverse outcomes (1–3 points according to GOS).

Conclusion. on hospital admission coagulopathy was diagnosed in 63,6% of patients in the acute phase of TBI, hypocoagulability state prevailed. Coagulopathy was signiﬁcantly more common in patients in the acute phase of severe TBI (GCS8 points).

The mechanisms of TBI-associated coagulopathy have not yet been fully clariﬁed. Further studies of the role of platelet, plasma and ﬁbrinolytic components in the development of coagulopathy are warranted, which require more comprehensive methods of hemostasis investigation.
Smart Mode of Mechanical Lung Ventilation During Early Activation of Cardiosurgical Patients
Authors: Eremenko A. A. , Komnov R. D.
Published: March 2020

Purpose of the study: a comparative assessment of safety and quality of respiratory support carried out using the ASV mode vs. conventional protocol, in which ventilation parameters are set by an ICU physician during early postoperative period in cardiosurgical patients.

Materials and methods. The modes of a respiratory support included automated ASV ventilation (40 patients) versus conventional ventilation (38 patients) managed by 8 ICU physicians were compared in a cohort of cardiosurgical patients in a randomized controlled study.

The comparison included ventilation parameters, all eﬀorts of physicians to adjust ventilator settings and time it took, duration of respiratory support in ICU, incidence of adverse events in the course of weaning, total time in ICU and hospital, postoperative complications and mortality.

Results. There was no reliable diﬀerence in the duration of postoperative trachea intubation, which was equal to 267±76 minutes (the ASV group) and 271±80 minutes (the control group).

The number of manual adjustments, which was 2 vs. 4 (P<0.00001), and the time spent by a clinical physician near a ventilator, which was 99±35 seconds vs. 166±70 seconds, were reliably lower in the ASV group (P=0.00001).

The time between restoration of patient’s own respiratory activity and transfer to the assisted breathing mode was longer in the control group and amounted to 30 (0–90) min. while in the smart mode, the transfer took place immediately after restoration (P=0.004969).

When ASV was used, the driving pressure was reliably lower during all phases of respiratory support: ΔP 7.2±1.6 vs. 9.3±2.1 cm H2O, (P=0.000001); there was no reliable diﬀerence in the tidal volume: 7.0 (6–8.5) (ASV) vs. 7 (6–10) ml/kg/ideal body mass (the control group).

Conclusion. ASV represents a lung-protective ventilation that reduces physician’s time cost and medical staﬀ eﬀorts in ALV management without compromising patient’s safety and respiratory support quality.
Models of Ischemic Stroke (Review)
Authors: Golubev A. M.
Published: March 2020

The incidence of ischemic stroke remains high in many countries, despite a declining trend in the incidence of brain circulation disorders. Limited knowledge of the pathogenesis, diagnosis, clinical presentation, and treatment of this life-threatening disease can be complemented by modelling of ischemic stroke on animals, particularly, in rodents (rats, mice).

The aim of review: to provide a rationale for choosing an optimal model of human ischemic stroke.

Among more than 300 primary literature sources from various databases (Scopus, Web of science, RSCI, etc.), 84 sources were selected for evaluation, of which 72 were published in the recent years (2015–2019). The criteria for exclusion of sources were low relevance and outdated data.

The review examined six experimental models of acute cerebrovascular events including middle cerebral artery occlusion, embolic stroke model; phototrombosis; models using thrombin, endothelin-1 and electrocoagulation of the middle cerebral artery.

The review outlines the factors inﬂuencing reliability and reproducibility of research results, related to adherence to the rules of animal accommodation and acclimatization, nutrition and care, selection of anesthesia and pain relief methods, compliance with aseptic techniques, monitoring of basic physiological parameters at all stages of the ischemic stroke modeling experiment, with humane withdrawal of animals from the experiment.

It was concluded that the model of ischemic stroke, based on the occlusion of the middle cerebral artery, is most promising as being the closest to features of human ischemic stroke and enabling to obtain reproducible results in the experiment.
AN EFFECTIVE OF POGIL WITH VIRTUAL LABORATORY IN IMPROVING SCIENCE PROCESS SKILLS AND ATTITUDES: SIMPLE HARMONIC MOTION CONCEPT
Authors: Alatas Fathiah , Fachrunisa Ziah
Published: March 2020

EFEKTIVITAS POGIL DENGAN LABORATORIUM VIRTUAL DALAM PROSES MENINGKATKAN KETERAMPILAN DAN SIKAP ILMU PENGETAHUAN: KONSEP MOTION MOTION SIMPLE HARMONIC AbstractSimple harmonic motion is a concept that often involve complex and difficult equations, so that students can’t construct knowledge of the concept. This research applies POGIL with a virtual laboratory, where students are encouraged to construct the concept and emphasize collaborative learning with different roles. Virtual laboratory allows students to explore and establish students’ science process skills and attitude. This study used a quasi experiment with nonequivalent control group design. Therefore, this study has add to the practical knowledge to develop science process skills and establish a positive attitudes of students toward science.AbstrakGerak harmonik sederhana merupakan konsep yang sering melibatkan persamaan yang rumit dan dianggap sulit, sehingga siswa tidak dapat membangun pengetahuan terhadap konsep. Penelitian ini menerapkan model POGIL dengan virtual laboratorium, dimana siswa didorong untuk mengkontruksi konsep dan menekankan belajar kolaboratif dengan peran berbeda. Virtual laboratorium memudahkan siswa untuk bereksplorasi. Ini menumbuhkan keterampilan proses sains serta sikap ilmiah siswa. Metode penelitian yang digunakan adalah quasi eksperiment dengan desain nonequivalent control group. Oleh karena itu, penelitian ini menambah pengetahuan praktis untuk mengembangkan keterampilan proses sains dan menumbuhkan sikap positif siswa terhadap sains.
DEVELOPING METACOGNITIVE SKILL INSTRUMENT ON FUNGUS CONCEPT
Authors: Zulfiani Zulfiani , Herlanti Yanti , Rosydatun Eny S. , Hasiani Silak , Rohmatulloh Ghina , Zuqistya Nila
Published: March 2020

PENGEMBANGAN INSTRUMEN KETERAMPILAN METAKOGNITIF PADA KONSEP JAMURAbstractMetacognition involves critical thinking skills, reflective of the cognitive processes of learners who simultaneously monitor their learning success. This research is aimed to develop metacognitive skill instrument on the mushroom concept of class X students of SMA Negeri in South Tangerang. Development research method / Formative Research from van den Akker (2006) with cycle/spiral process: analysis, design, evaluation and revision, systematic reflection and documentation. The metacognitive skills instrument consists of 12 questions, with the construction of 3 high order thinking skill, open-ended, cognitive thinking questions with 9 questions of metacognitive skills (planning, monitoring, and evaluation). Instruments validated through expert judgment and trial test were limited to 38 students and obtained Cronbach Alpha value of 0.832 (high criterion). The instrument was then revised and  re-tested on 96 learners and obtained by Alpha Cronbach 0.746 (high category). The results of this study acquired an alternative method of metacognitive skills measurement of learners are integrated into the biology of learning in the classroom.AbstrakMetakogisi melibatkan keterampilan berpikir kritis, reflektif terhadap proses kognitif peserta didik yang secara simultan memantau keberhasilan belajarnya. Penelitian ini bertujuan mengembangkan instrumen keterampilan metakognitif pada konsep Jamur peserta didik kelas X SMA Negeri di Tangerang Selatan. Metode penelitian pengembangann atau development research dari van den Akker (2006) dengan proses siklus/spiral: analisis, desain, evaluasi dan revisi, refleki sistematik dan dokumentasi. Instrumen keterampilan metakognitif berjumlah 12 pertanyaan, dengan konstruksi  3 pertanyaan kognitif berpikir tingkat tinggi, open ended disertai 9 pertanyaan keterampilan metakognitif (perencanaan, monitoring, dan evaluasi). Instrumen divalidasi melalui expert judgment dan uji coba terbatas pada 38 peserta didik dan diperoleh nilai reliabilitas Alpha Cronbach 0.832 (kategori tinggi). Instrumen kemudian direvisi dan diuji coba kembali  pada 96 peserta didik dan  diperoleh nilai Alpha Cronbach 0.746 (kategori tinggi). Hasil penelitian ini diperoleh alternatif metode pengukuran keterampilan metakognitif peserta didik yang terintegrasi dalam pembelajaran biologi di kelas.
THE DEVELOPMENT OF INTEGRATED SCIENCE PRACTICE ON SKIN HEALTH THEME ‎TO ENHANCE THE SCIENCE PROCESS SKILL OF JUNIOR HIGH SCHOOL STUDENTS ‎
Authors: Purnamasari Shinta , Surtikanti Hertien
Published: March 2020

Science learning have to able to provide direct experiences to the students, so they not only learn the  concepts and theories, but also can learn science as a process through lab activity. In middle school,  science  learning  conducted  in  integrated  mode  in  order  to  provide  opportunities  for  students  to understand the phenomenon from various sides. The aim of this study was to produce an experiment procedure to teach integrated science in skin health theme that can be implement it in learning process.  A hands-on activity is presented in worksheet form. This study used Research and Development method. The stages were conducted in this study consist of preliminary studies and model development. Data collected through experts assessment sheet, and readability questionnaire and science process skills test. Based on experts assessment sheet obtained that experiment procedure has a good quality with average percentage about 90.56% which includes didactic aspect (93.21%), construction aspect (88.89%), and  technical  aspect (91.67%). An experiment procedure was presented in worksheet form andhas a very  good readability level with average percentage about 82.80%. The test result showed that an experiment  procedure can enhance students’ science process skills especially in doing an experiment aspect. Keywords: experiment development; integrated science experiment; skin health; sunscreen.
THE DEVELOPMENT OF BIOLOGY PRACTICE IN HIGH SCHOOL SCHOOL BASED ON ‎ETHNOBIOLOGY
Authors: Sunaryati Siti , Suatma Suatma Suatma , Miranda‎ Yula
Published: March 2020

Local knowledge of the Dayak Ngaju community in Gunung Mas regency, Central Kalimantan there were believed that many species of plants, animals and their surroundingscan be used as an indicator of a particular environtment. The local people experience is one example of local knowledge which needs to be studied scientifically through ethnobiology.Study of ethnobiology was confined to the local community's knowledge about the medicinal plants (ethnobotany), local community knowledge about the utilization of existed nearby animals (ethnozoology) and knowledge of the local community in ecosystems around their living quarters (ethnoecology). Afterwards these studies was arranged into biology practical work material. The purposesof the studyare(1) to study theethnobiology of local knowledge of DayakNgajucommunitiesinGunung Mas regency, (2) to inventoryandidentifyseveral species that areusedin foodstuffs, pharmaceuticals, industry and utilization of the environment for the practical work in high school. This should be well documented and to be taught to the next generations to avoid the extinction of local knowledges.Integratingthe materialethnobiology into learningbiology is one of the best ways to deliverlocalknowledge in formal education. It was suggested to teach ethnobiology inbiology practical work, especially inhigh school who have forest environment as characteristic oftheir territory since ethnobiological material was very important. Keywords:ethnobiology; practical work;high school.
PRINCIPLES OF PUBLIC ADMINISTRATION OF STAFFING OF THE NATIONAL POLICE OF UKRAINE
Authors: Romashov Yu. S.
Published: March 2020

It is emphasized that in order to fulfill the tasks assigned to the National Police of Ukraine, a stable and highly professional staff is required, capable of properly responding to the challenges and threats in the sphere of internal affairs. Therefore, the purpose of the article is to identify and summarize the system of principles of public administration of personnel support of the National Police of Ukraine on the basis of the theory of administrative law, the analysis of relevant normative-legal domestic and foreign acts, works of scientists and other sources. Thus, in the scientific work the system of principles of public administration of personnel support of the National Police of Ukraine was identified and described as the basic principles of the realization of public power in order to satisfy the society with professional, conscientious, ethically educated police officers, who can potentially carry out preventive activities and restore the rights and freedoms of the process crimes. It is determined that the principles of public administration of personnel of the National Police of Ukraine are the basic provisions, guiding ideas, norms of behavior, which are formulated in the form of a certain scientific provision and are fixed mainly in the legal form, reflect the content, structure, forms and methods of public administration of human resources for law enforcement agencies for the purpose of satisfying the public with professional, conscientious, ethically educated police officers to carry out the tasks assigned to the bodies and units of the National Ukrainian police. It is concluded that the principles of staffing of the National Police of Ukraine should be divided into general (rule of law, legality, political neutrality, integrity, transparency and openness, interaction with the public, patriotism, science, efficiency, competence) and functional-managerial principles (hierarchical, distribution of powers, collegiality and sole command, accountability, quality staffing of the National Police bodies to ensure legal and social workers, etc.).
FORMATION (ORIGIN) INTENTIONS AS PART OF THE CRIME
Authors: Kapustin O. B.
Published: March 2020

The purpose of the article is the scientific consideration and legal analysis of intent as a part of a crime. Intent is a legal category known in law. According to the Criminal Code of Ukraine, an act committed with direct intent or indirect intent is recognized as a crime committed intentionally.
It is known that vast majority of crimes stipulated by the criminal law is premeditated crimes. The vast majority of crimes committed in real life is also premeditated crimes. Premeditated crimes are the most dangerous crimes, and because of this, most attention of law enforcement officers is focused on them, causing the greatest public outrage. Relevance of the topic: Analysis of the latest research and publications.
In spite of this, in my opinion, the matter of intent is not quite largely highlighted in the domestic scientific literature.
For the past 25 years, there has been virtually no domestic research at the dissertation and monograph levels devoted to study of the intent. There are only fragmentary references to this notion in cases of exploring different topics. A similar situation is typical for scientific articles. Therefore, specific coverage of this issue is a gap in modern science and has scientific novelty. This article is intended to fill this gap.
The article deepens the doctrine of intent as a part of a crime. It is stated in the article that the overwhelming majority of crimes, stipulated by the rules of criminal law, are premeditated crimes. It is noted that the initial stage of the crime is formation of intent, which, at the initial stage often does not have any external manifestation. It is established in the article that the formation of intent and its detection in the obligatory presence of at least one of the following stages in development of criminal activity should be attributed to the non-punishable stages of development of the crime. This article does not cover all legislative and legal aspects of the intent.
The prospect of further research is, in particular, the problem of adequate legislative reflection of the danger of intent. I consider it necessary to continue research in the field of the moment of intent.
CIVIL CLAIM IN A CRIMINAL PROCEEDING IN UKRAINE AS A MEANS
OF GUARANTEE AND PROTECTION OF INDIVIDUALS’ RIGHTS
Authors: Tymoshenko O. A.
Published: March 2020

The article deals with analyzing the state of the civil claim scientific research in criminal proceedings in Ukraine and summarizing it. It was determined the relevance of scientific rethinking of the phenomenological foundations of a civil claim in criminal proceedings. It is proved that the importance of the mechanism of criminal justice has the issue of legal support of the institute of civil claim, as an important component of guaranteeing and protecting the rights and freedoms of citizens. First of all, this is explained by the importance of a civil claim in criminal proceedings, its actual role that a civil claim plays in the justice system, ensuring the protection of the violated rights of citizens.
On the basis of the state critical analysis of a civil claim legal support in criminal proceedings in Ukraine, it was determined its components and given their characteristics, which include: 1) the subjective component of the legal relations relating to civil claim in criminal proceedings in Ukraine; 2) the procedural issues of filing and considering a civil claim; 3) legal and technical requirements relating to the form and content of the civil claim.
It was made and justified the provisions concerning the prospects of improving the civil claim mechanism functioning in criminal proceedings in Ukraine.
Transformation of scientific understanding and practical perception of civil claim in criminal proceedings as a means of securing and protecting human rights and freedoms has been proved, on the basis of which the directions of improving the functioning of the said legal institute in Ukraine are distinguished, namely: 1) enhancing the role and importance of the European Court of Justice’ s activities human rights in extending his practice to litigation in criminal proceedings in Ukraine; 2) strengthening the mechanisms of human rights protection at the domestic (national) level in accordance with the requirements of international law, which are a component of civil claim in criminal proceedings; 3) improve the procedure for enforcement of the decisions of the national courts of Ukraine in the part related to civil claim in criminal proceedings, etc.
CONCEPTUAL BASIS OF DEFINITION OF STATE DEVELOPMENT
STRATEGY OF UKRAINE
Authors: Bostan S. K.
Published: March 2020

In the article it was noted, that the new ukrainian government is trying to decide the problems in the ukrainian’s society, but its actions are directed first of all at the achievement of the short-term, specific tasks to stabilize the situation in the country. It was emphasized, that its actions can produce some positive results, but the maximum level of their effectiveness can will be, if these tactical tasks will be realized on the basis of long term state strategy. It is determined that the state strategy is a moving social contract social contract concluded by the state government with citizens for a certain period and providing for perspective and long-term planning of the state development. The importance of the state strategy consists in openly proposals of the social values. It founds the basics for the social solidarity in achieving goals and so it constituted the state as unity power. The expediency of establishing a long term for implementing a state development strategy in Ukraine and building a democratic, social state of law as its ultimate goal have been paid attention to.
It was emphasized that the determination of the constituent elements of a state strategy can be accomplished by the division of the state as an object of strategic planning into a number of “sub-objects” that have more specific short or medium-term tactical goals in the process. It was suggested that to rely on the scientific apparatus of the theory of state and law for defining these “sub-objects”. But it is a basic fact that the state as a social phenomenon consists of three main components, namely: form, content and essence. It was pointed out the form of the state as an external expression of the content and essence of the state, which are manifested through such elements as the form of political regime, form of state government and form of state-territorial structure. It was stressed out that the content is a sort of ordered set of institutional elements that make up the state. The essence of the state is a set of features of the state, which in unity reflect its qualitative properties, manifested through the functions of the state. It was were summarized that through consideration such elements should determine the long-term of development of the Ukrainian state, which will allow to optimize the process of political-public administration and to ensure its stability, consistency and continuity, based on clearly formulated long-term objectives.