bluuebunny/crossref_metadata_2025 huggingface dataset:
Penampungan Semen yang Terlalu Sering Menurunkan Daya HidupSpermazoa pada Ayam Onagadori
Authors: Dendang Mawar Datu Allo , Bebas Wayan , Trilaksana I Gusti Ngurah Bagus
Published: June 2024

One of the unique ornamental chickens that is in great demand by ornamental chicken enthusiasts is the long-tailed chicken or onagadori chicken originating from the city of Nankoku Kochi, Japan. This study was aimed to determine the effect of the frequency of semen collection on spermatozoa quality in onagadori chickens. In the study used a completely randomized design (CRD) with three treatment groups using eight onagadori chickens with an age range of 6-7 months. The first treatment (P1), was cement collection carried out every six days or once a week; the second treatment (P2) was cement collection carried out every three days or twice a week; the third treatment (P3) was cement collection carried out every two days or thrice a week. Each treatment was repeated three times. Observations were made on the quality of onagadori chicken spermatozoa. Semen collection once a week produces a volume of 0.087 mL; concentration 4.7 billion cells/mL; motility 84.66%; abnormality 8.46%; viability 81.44%. Semen collection twice a week produces a volume of 0.09 mL; concentration 4.9 billion cells/mL; motility 83.22%; abnormality 9.1%; viability 83.87. Semen collection three times a week produces a volume of 0.09 mL; concentration 4.7 billion cells/mL; motility 83.57%; abnormality 8.54%; viability 82.32%. The data obtained was analyzed by Analysis of Variant and then followed by the Least Significant Difference (LSD) test. The results showed that the frequency of semen collection at P1, P2, and P3 on volume and concentration, motility, and abnormalities yielded no significant differences (P>0.05), while viability showed significant differences (P<0.05).
Total Eritrosit, Kadar Hemoglobin, Nilai Hematokrit, dan Indeks Eritrosit Anjing Penderita Dermatitis Atopik Pascaterapi dengan Eco Enzyme
Authors: Gunawan Stephanie Ariella , Suartha I Nyoman , Dharmawan Nyoman Sadra
Published: June 2024

Atopic dermatitis is a common skin disorder in dogs. This study was aimed to determine the effect of eco enzyme on dogs suffering from atopic dermatitis in terms of changes in total erythrocytes, hemoglobin levels, hematocrit values and erythrocyte indices. Two groups of dogs with atopic dermatitis were used in this study: concentration A (three dogs) were bathed with 10% concentration of eco enzyme at intervals of three days, and concentration B (two dogs) were bathed with 10% concentration of eco enzyme at intervals of three days, then continued a week later with eco enzyme concentration of 2% at intervals once a week. Both groups were given treatment for five weeks. Hematology data were analyzed through tiered pattern analysis of variance followed by Duncan’s multiple range test using SPSS which showed that the concentration of eco enzyme and the duration of observation (weeks) had no significant effect on total erythrocytes, hemoglobin, hematocrit, MCH and MCHC, although they influenced MCV. Also, there was a real interaction between the concentration of eco enzyme and the duration of observation at MCH. It can be concluded that therapy with eco enzyme has not been able to improve total erythrocytes, hemoglobin, hematocrit, MCH and MCHC, but has been able to improve MCV in dogs with atopic dermatitis.
Spod tynku patrzy... mnemotopos? O poniemieckich inskrypcjach we Wrocławiu
Authors: Seń Aleksandra
Published: June 2024

Artykuł nawiązuje do niepublikowanego wcześniej tekstu prof. Stefana Bednarka i Justyny Harbanowicz dotyczącego mnemotoposów Wrocławia. Zawiera wprowadzenie teoretyczne na temat pamięci zbiorowej, jej relacji z historią, pojęcia miejsc pamięci i mnemotoposów — terminu proponowanego przez Profesora. Następnie poddaje analizie projekt „Spod tynku patrzy Breslau”, mający na celu zmapowanie przedwojennych szyldów reklamowych i innych inskrypcji we Wrocławiu. Przywołane zostają dwa przykłady szyldów, w których materializują się wrocławskie mnemotoposy.
Zdarzenia po dniu bilansowym w praktyce spółek notowanych na GPW
Authors: Soja Klaudia
Published: June 2024

Artykuł ma na celu identyfikację zdarzeń występujących po dniu bilansowym, wskazanie sposobu ich prawidłowego ujęcia i prawidłowej prezentacji w sprawozdaniu finansowym w świetle rozwiązań krajowych i międzynarodowych oraz weryfikację sposobu ujawniania tych zdarzeń przez przedsiębiorstwa i ich wpływu na sporządzone sprawozdanie finansowe. Analizę przeprowadzono na podstawie literatury przedmiotu oraz sprawozdań finansowych wybranych spółek notowanych na Giełdzie Papierów Wartościowych w Warszawie, sporządzonych za lata 2018–2021. Na podstawie analizy określono liczbę i zakres takich zdarzeń w praktyce polskich przedsiębiorstw. Niniejsza publikacja uzupełnia dorobek naukowy z zakresu sprawozdawczości zdarzeń po dniu bilansowym oraz ich wpływu na informacje prezentowane w sprawozdaniu finansowym.
Glosa do wyroku Sądu Najwyższego z dnia 22 czerwca 2021 roku (sygn. II DK 56/21)
Authors: Modrzejewska Klaudia
Published: June 2024

Glosa przedstawia problematykę niesprecyzowania deliktu dyscyplinarnego, który godził w Kodeks etyki radcy prawnego. Zbyt ogólne sformułowanie cech bezprawności jest przyczyną niemożności zakwalifikowania zachowania jako czynu zabronionego. Sąd Najwyższy podkreślił, że opis zarzucanego czynu w postępowaniu musi być bardzo dokładny, aby było oczywiste, jakie działania są dozwolone, a jakie zakazane. Celem glosy jest zwrócenie uwagi na kwestię standardów postępowania, zwłaszcza na precyzyjne określenie czynu zagrożonego karą.
Utworzenie stałego zakładu podmiotu zagranicznego przez działanie spółki zależnej w Polsce
Authors: Olewińska Marta
Published: June 2024

Zamierzeniem niniejszego artykułu jest przybliżenie sytuacji, które mogą powodować powstanie stałego zakładu podmiotu zagranicznego w Polsce wskutek kooperacji podjętej z polskim podatnikiem w świetle komentarza do Konwencji modelowej OECD z 2017 roku. W szczególności celem artykułu jest próba oceny, które aktywności podmiotu polskiego w stosunku do zagranicznego podmiotu powiązanego mogą wykraczać poza przygotowawczy i pomocniczy charakter. Autorka podjęła się zbadania wpływu poszczególnych komentarzy OECD na bieżący sposób oceny tych aktywności i wskazała charakterystyczne przykłady działań mogących wykreować stały zakład w Polsce. Poruszyła także dyskusyjną kwestię sposobu wykładni poszczególnych zmian Konwencji, a także komentarza do niej przy stosowaniu definicji stałego zakładu w umowach o unikaniu podwójnego opodatkowania.
Legitymacja procesowa małżonków występujących w postępowaniu cywilnym — studium przypadków. Część 2
Authors: Bury Paweł , Kowalski Rafał
Published: June 2024

Niniejszy artykuł kontynuuje zagadnienia związane z kwestią legitymacji procesowej małżonków w postępowaniu cywilnym. Omówieniu i analizie poddano poszczególne przypadki występowania małżonków w procesie.
Międzypłciowa luka płacowa a problem segregacji zawodowej i dyskryminacji
Authors: Radwan Magdalena
Published: June 2024

Międzypłciowa luka płacowa jest aktualnym zagadnieniem ze względu na problem równości płci na rynku pracy. Różnice w zarobkach pomiędzy kobietami a mężczyznami to z kolei konsekwencja wielu czynników, do których należy między innymi segregacja zawodowa. Celem tego artykułu są więc teoretyczne rozważania nad istotnością segregacji zawodowej w odniesieniu do międzypłciowej luki płacowej, jak również analiza zjawiska dyskryminacji w kontekście omawianej segregacji oparte na dekompozycji Oaxaki–Blindera. W artykule postawiono tezę, że segregacja zawodowa zaliczana na ogół do jednego z komponentów składnika wyjaśnionego luki płacowej może być wynikiem nierównego traktowania.
Countermeasure of Protection Against Local Scouring Downstream of Concrete Check Dams
Authors: Yasuda Youichi , Wang Jiayu
Published: June 2024

Check dams are planned to control sediment and gravel runoff during floods. In accordance with the planning for the Sabo works, check dams have been constructed in each watershed, which may reduce serious sediment transport during floods. On the other hand, as the ratio of the installation of check dams to the planning is proceeded, sediment transport is limited, and degradation of the riverbed has been observed downstream of check dams. In general, localized scouring was observed downstream of the sub-dam even after protection blocks were installed downstream of the check dam. This may be caused by the lack of functionality to raise the main flow in the protection blocks. In concrete check dams, there are different types of ordinary closed check dams and check dams silted at a center part of dam. In terms of countermeasures against local scouring downstream of the sub-dam, there is no difference of design method for different types of check dams. Recently, the ramp with consecutively assembled boulders was proposed by Yasuda, the installation of the ramp below low drop structure is effective for both protection of river bed during flood stages and migration of multi-aquatic animals for normal stages. This paper presents that the installation of the ramp with consecutively assembled boulders downstream of a sub-dam is effective for different types of check dams. Experimental results show that the thee-dimensional main flow through the sub-dam can be controlled by the formation of seepage flow in the ramp composed by the assembled boulders, and that the main flow always rises toward the water surface at the downstream end of the ramp. The cross section of the ramp has a parabolic shape, and the velocity near the sidewall can be reduced in comparison with the center part of the ramp during flood stages. In addition, the migration for the multi-aquatic animals on the ramp is possible during normal stages as in the case of low drop structure.
Indonesia's Breakthrough in Maximizing Wind Energy Efficiency Through Optimized Blade Configuration
Authors: Prasetiyo Rohmad Arvendo Yoga , Firdaus Eng Rahmad
Published: June 2024

Indonesia faces rising energy demand, risking an energy crisis and increased fossil fuel dependence. This study explores using NACA 0021 airfoil blades to improve wind turbine performance by analyzing the effect of different rotor blade numbers. Conducted at Universitas Muhammadiyah Sidoarjo, the research tested turbines with 2, 3, and 4 blades, measuring current, voltage, power, and efficiency. Results showed that more rotor blades enhance turbine performance, increasing current and voltage output. This suggests optimizing blade configurations can significantly boost small-scale wind energy systems, helping reduce fossil fuel reliance and mitigate the energy crisis.
Highlights:
1. More rotor blades boost turbine performance: increased current and voltage.2. NACA 0021 airfoil optimizes small-scale power generation.3. Effective blade configuration reduces fossil fuel reliance, mitigating energy crises.
Keywords: wind energy, NACA 0021, rotor blades, turbine performance, renewable energy
Lock and Dam 25, Upper Mississippi River Navigation Study : ship-simulation results
Authors: Pazan Kiara , Memarsadeghi Natalie , Hodges Jacob
Published: June 2024

The US Army Engineer Research and Development Center, Coastal and Hydraulics Laboratory (CHL), used the Ship/Tow Simulator to evaluate navigational conditions for the US Army Corps of Engineers, St. Louis District (MVS), proposed 1,200 feet (ft) lock chamber at Lock and Dam 25 in a tow simulation study. The study considers the impacts to navigation throughout construction sequences of the proposed 1,200 ft lock chamber and the final completed project. Testing occurred at CHL in October–November 2022 with five industry tow pilots. A total of 47 unique test conditions for a total of 187 ship-simulation exercises were evaluated. All final project simulations indicated that the design is feasible. When testing the construction scenarios of the design, it was evident that a tug-assist boat would be necessary for entering the 600 ft lock for both approaches. Results found that the intermediate wall construction should begin at the existing structure and progress downstream. Entering the 600 ft lock from the pool side was additionally completed successfully; however, modifications are needed for entering from the tailwater side. Ultimately, the results of this study will aid MVS in the design plan and decision-making regarding the proposed lock.
Upaya Meningkatkan Minat dan Hasil Belajar Matematika menggunakan Media Juku Kelas II di Sekolah Dasar
Authors: Fajarani Hanifan , Choiriah Widyasari
Published: June 2024

Penelitian ini bertujuan untuk meningkatkan minat dan hasil belajar matematika menggunakan media “JUKU”. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK), yang dilakukan melalui empat tahap yaitu perencanaan, tindakan, observasi, dan evaluasi/refleksi. Subjek penelitian ini adalah peserta didik kelas IIB SD Muhammadiyah 23 Surakarta, dengan jumlah 28 peserta didik. Data penelitian ini diperoleh melalui observasi dan tes tertulis yang diberikan oleh peneliti melalui soal evaluasi. Hasil penelitian yang diperoleh yaitu minat dan hasil belajar matematika materi penjumlahan dan pengurangan peserta didik meningkat. Pada siklus I diperoleh hasil rata-rata untuk minat belajar matematika peserta didik dengan persentase 68,74% dan pada siklus II peserta didik telah mengalami peningkatan dengan persentase 87,71%. Selain itu, hasil belajar matematika peserta didikpun juga meningkat. Dari persentase rata-rata hasil belajar pada siklus I sebesar 69,39% dan persentase ketuntasan sebesar 60,71%. Kemudian pada siklus II terjadi peningkatan rata-rata hasil belajar sebesar 88,67% serta persentase ketuntasan belajar juga meningkat sebesar 85,71. Sehingga dapat disimpulkan bahwa telah terjadi peningkatan pada minat dan hasil belajar matematika peserta didik setelah diberikan perlakuan menggunakan media “JUKU”.
ZDKD-FLID:Zero-Data Knowledge Distillation of Federated Learning for Intrusion Detection
Authors: Gao TiaoKang , Jin XiaoNing , Lai Yingxu
Published: June 2024

Over the years, federated learning-based intrusion detection has attracted attention because it preserves data privacy and improves the detection capabilities of local models. However, the majority of existing methods in this domain are tailored for homogeneous models. Given the impact of factors such as hardware disparities and business requirements, local models often exhibit heterogeneity, which significantly restricts the development and application of federated learning for intrusion detection. Therefore, to address the challenge posed by model heterogeneous federated learning-based intrusion detection, this paper proposes a novel framework called zero-data knowledge distillation of federated learning for intrusion detection (ZDKD-FLID). This framework not only effectively addresses the issue of model heterogeneity but also operates without relying on a public dataset. Firstly, on the node side, the prediction model and local model perform knowledge distillation learning. Secondly, on the server side, the prediction model is selected and aggregated to generate a global prediction model. Additionally, a generator optimized with particle swarm optimization is employed for generative adversarial learning, enabling the generation of samples. Finally, the local model is trained using samples containing knowledge from other heterogeneous models, effectively improving the accuracy of intrusion detection. To validate its efficacy, ZDKD-FLID is compared with state-of-the-art algorithms on the CICIDS-2017 and UNSW-NB15 dataset. Consequently, ZDKD-FLID demonstrates superior performance compared to all the other considered algorithms.
Considering Planetary Health in Health Guidelines and Health Technology Assessments: A Scoping Review Protocol
Authors: Piggott Thomas , Raja Maheen , Michels Charlotte T.J. , Herrmann Alina , Scahill Karolina , Darzi Andrea J. , Jewell Laura , Saif-Ur-Rahman KM , Napierala Hendrik , Heuer Ruben , Morgan Rebecca L. , Leontiadis Grigorios I. , Neumann Ignacio , Schünemann Holger , Miller Fiona A.
Published: June 2024

Background
This protocol outlines a scoping review with the objective of identifying and exploring planetary health considerations within existing health guidelines and health technology assessments (HTA). The insights gained from this review will serve as a basis for shaping future Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) guidance on planetary health.
Methods
We will adhere to the JBI methodology for scoping reviews. We will conduct a comprehensive search and screening of results in all languages across various databases including MEDLINE, EMBASE, CINAHL, Global Health, Health Systems Evidence, Greenfile, and Environmental Issues. Additionally, we will supplement this search with resources such as the GIN library, BIGG database, Epistemonikos, GRADE guidelines repository, GRADEpro Guideline Development Tool Database, MAGICapp, NICE website, WHO websites, and a manual exploration of unpublished relevant documents using Google incognito mode. Two independent reviewers will screen and assess full texts of identified documents according to the eligibility criteria. The following information from each full text will be extracted: document title; first author’s names; publication year; language; document type; document as a guideline or HTA; the topic/discipline; document purpose/study objective; developing/sponsoring organization; country in which the study/guideline/HTA report was conducted; definition of planetary health or related concept provided; types of planetary health experts engaged; study methods; suggested methods to assess planetary health; use of secondary data on planetary health outcomes; description for use of life cycle assessment; description for assessing quality of life cycle; population/intended audience; interventions; category; applicable planetary health boundaries; consideration of social justice/global equity; phase of intervention in life cycle related to planetary health addressed; measure of planetary health impact; impact on biodiversity/land use; one health/animal welfare mention; funding; and conflict of interest. Data analysis will involve a combination of descriptive statistics and directed content analysis, with results presented in a narrative format and displayed in tables and graphs.
Discussion
The final review results will be submitted to open access peer-reviewed journals for publication when they become available. The research findings will also be disseminated at relevant planetary health conferences and workshops.
Registration:
This scoping review protocol was registered in Open Science Framework (https://osf.io/3jmsa).
Which plays a more important role in hemophilia treatment, economical development or medical technology?
Authors: Yu Dan , Yang Shu , Mu Hongli , Zhou Zeping , Zhang Yiting , Tang Jialing , Huang Meijuan , Lai Yinghui
Published: June 2024

Objective: To investigatethe management status of hemophilia A patients in Fujian, Guangxi and Yunnan provinces in South China and their gaps with the national data. To explore which plays a more important role in hemophilia treatment, economical development or medical technology?
Methods: The data of hemophilia A patients registered in Fujian, Guangxi and Yunnan provinces were analyzed, and their diagnosis and treatment were studied and compared with the published national data.
Results: 542 hemophilia A cases were registered in Fujian, including mild ones 6.3%, moderate 73.2%, severe 12.6% and unknown 7.9%; 295 cases in Guangxi, mild 4.7%, moderate 22.7%, severe 30.5% and unknown 42.1%; 162 cases in Yunnan, mild 7.4%, moderate 45.1%, severe 42.6% and unknown 4.9%. The proportion of patients with severe hemophilia A in Fujian was significantly lower than that in Guangxi, Yunnan and national data (P < 0.05). Approximately29.2% had a delayed diagnosis in Guangxi (24.1% in Yunnan, 4.1% in Fujian, national data: 28.8%; P=0.000). The rate of delayed treatment is 17.3% in Guangxi, 4.9% in Yunnan,1.5% in Fujian and 39.2% in national data. The rate of joint deformity is 67.9% in Yunnan, 40.4% in Guangxi, 36% in national data and 17.0% in Fujian. The prophylactic treatmentrates in Guangxi and Yunnan were 16.9% and 27.2% respectively, which were statistically significant compared with the national rate (16.2%).
Conclusion: Diagnosis and treatment status of hemophilia A in the three southern provinces of China are significantly different from the national data. In hemophilia treatment, economical development plays a more important role.At similar economic levels, medical technology will cause a gap in the level of hemophilia treatment.
Clinical observation on warming needle moxibustion combined with rehabilitation techniques in the treatment of anterior disc displacement without reduction
Authors: Zhu Renjie , Yu Jing , Wang Fangli , Chu Jiamei , Bao Yehua , Wang Qin , Wei Yuanye , Yuan Jianhui
Published: June 2024

Objective: To observe the effect of warming needle moxibustion combined with rehabilitation techniques on clinical symptoms and quality of life of patients with anterior disc displacement without reduction (ADDwoR).
Methods: This randomized controlled trial included 66patients, with ADDwoR, attending the Hangzhou Hospital of Traditional Chinese Medicine. Patients were assigned to the Experimental (12 sessions of warming needle moxibustion combined with rehabilitation manipulation therapy) and Control (rehabilitation therapy only) group (n = 33, each). Duration of treatment was 4 weeks, with 3 times a week. Outcomes included VAS pain score, maximum mouth opening (MMO), mandibular function impairment score (MFIQ), oral health impact scale (OHIP-14 scale), and mandibular dysfunction index (Fricton score). Safety assessments during treatment included incidence of fainting, broken needle, bleeding, hematoma and scalding.
Results:
After treatment, the VAS scores, mandibular function impairment scores, oral health impact degree scale, and the scores of DI, PI and CMI in the two groups were significantly decreased compared with before. While the maximum mouth opening was increased in both groups. And the clinical efficacy evaluation was: the cure rate of the control group was 59%, and the cure rate of the experimental group was 83%. There was significant difference in the cure rate between the two groups.
Conclusion: Compared to targeted rehabilitation exercises only, warming needle moxibustion combined with rehabilitation manipulation can not only improve the pain and maximum mouth opening, but also mandibular function impairment, mandibular joint disorder and oral health of patients with ADDwoR.
Clinical trial registration: http://www.chictr.org.cn/index.aspx, identififier: ChiCTR2200059039.
CENPO as a potential biomarker for the prognosis and therapy of CSCC patients
Authors: Li Xiaoxin , Li Fei , Tian Yan , Zhang Ping , Cai Hong , Xu Feng
Published: June 2024

Background
Cutaneous squamous cell carcinoma (CSCC) is a common nonmelanoma skin cancer. There are limited targeted therapeutic options for treating CSCC.
Methods
This study explored the differential expression of CENPO in CSCC and its relationship with clinical prognosis via data from The Cancer Genome Atlas (TCGA) database. The CENPO gene knockdown lentivirus was constructed, and the biological function of CENPO was evaluated via CCK8 cell proliferation, scratch, invasion, and cell apoptosis experiments in vitro. Furthermore, CENPO was evaluated in vivo.
Results
The TCGA data and clinical immunohistochemical results confirmed that CENPO is significantly overexpressed in CSCC and that CENPO is upregulated with clinical grade. The CCK-8 results confirmed that cell proliferation decreased with CENPO knockdown. Scratch experiments confirmed that cell migration decreased with CENPO knockdown. The invasion experiments confirmed that the cell invasion ability decreased with CENPO knockdown. Flow cytometry experiments showed that cell apoptosis increased with CENPO knockdown. The in vivo assay results showed that the tumor growth rate significantly decreased with CENPO knockdown.
Conclusions
The proliferation, invasion, migration, and antiapoptotic ability of CSCC cells are enhanced by upregulating CENPO. The activity of CSCC cells was significantly inhibited by CENPO knockdown. CENPO could serve as a new biomarker for the diagnosis and treatment of CSCC.
Mitochondrial genome of Machilus pauhoiassembly highlighted the structure variation through long repetitives in ANA species
Authors: Zhao Kai , Shen Mingli , Zheng Ruiyue , Peng Yukun , Chen Jiemin , Zhu Xuanyi , Luo Xianmei , Tong Tong , Xie Jianlian , Ahmad Sagheer , Zhou Yuzhen , Zhong Quanlin , Li Baoyin
Published: June 2024

Background
Plant mitochondria exist and function in a special way, this third-kind genetic material is essential for plant growth and development. However, its complex and highly variable genome structure lead to a poor understanding compared with chloroplasts.
Results
With the help of HIFI sequencing, we obtained new insights of their structure and functions. Machilus pauhoi (Magnoliaceae), an indigenous species, showcases a profusion of metabolites, elegant growth traits like bright red fresh leaves and straight trunk. Thus, we initially curated complete reference mitochondrial genomes for Machilus pauhoi. Though still regarded as complex structure, a 775 Kb two-circle physical map exhibiting simplification trend through one long lateral repeat region in ANA grade. Comparisons of consistent sequences revealed significant large-scale and inclined rearrangements within both cytoplasmic and nuclear genomes. Furthermore, the identification of lateral transfers from chloroplast to mitochondrial genome highlighted the consistent capture of functional genes such as petN. Besides, transferred sequences displayed chromosomal preference in nuclear genome, including genes like cytb, ATP9 and mRpL2. Aberrant selective pressure occurred for ccmB in Magnoliales though mitogenomes bore a greater burden of pressure compared to genes in the chloroplast. We also presented the expression of mtgenes , emphasizing a relatively functional concentration in no chloroplast tissues.
Conclusion
Eventually, the assembly of our newly acquired mitogenome contributes valuable insights into the evolutionary patterns observed in higher plant mitogenomes, thereby establishing a robust foundation for future industrial advancements in functional exploration of forest species.
Effect of foot type on electromyographic characteristics and synergy of selected lower limb muscles during running
Authors: Hajilou Behrouz , Esmaeili Hamed , Anbarian Mehrdad
Published: June 2024

Background
The purpose of the present study was to examine the effect of foot structure on the electromyography factors and the synergy of the selected muscles of the lower extremity.
Methods
The activity of eight lower limb muscles during running was recorded at 3.3 m/s from 60 beginner runners with different foot structures during running. Also, muscle synergies were extracted using non-negative matrix factorization algorithm.
Results
The results showed that there were differences between groups with different foot type in muscle activity under different phases of running in some muscles. Furthermore, the findings indicated that the number of synergies was similar in different groups and the relative weight of muscles was not different across groups.
Conclusion
Despite the difference in muscle activity under different phases of the running cycle, muscle synergies are similar among the groups. This can indicate similar control by the central nervous system in runners with different arch structures while running and the observed changes in muscle activity can be attributed to the type of forces exerted on the body, the length-tension relationship, and changes in the direction of the lower limbs in people with different arch structures.
Association between cognitive dysfunction, TYG index, and depression in older adults: based on the NHANES database, 2011-2014
Authors: Guo Qinghua , Guo Libo , Wang Yong , Shang Shaomei
Published: June 2024

Background
The relationship between cognitive impairment, triglyceride-glucose (TyG) index, and depression in the elderly remains unclear. This study aims to explore the associations among cognitive impairment, TyG index, and the risk of depression in older adults, providing a basis for targeted prevention strategies.
Methods
This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9). Cognitive impairment was defined as the lowest quartile of three cognitive tests: the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) test for learning and memory, the Animal Fluency test for executive function, and the Digit Symbol Substitution Test (DSST) for attention and processing speed. The TyG index was calculated as ln [triglycerides (mg/dL) × fasting glucose (mg/dL) / 2], and participants were categorized into quartiles based on their TyG index. Multivariable logistic regression models were employed to investigate the relationships between cognitive impairment, TyG index, and depression in the elderly.
Results
A total of 2042 elderly participants (aged ≥ 60 years) were included in the study, among whom 312 (15.3%) were diagnosed with depression. Both cognitive impairment and higher TyG index were significantly associated with increased depressive symptoms among older adults in the United States. The risk of depression was 2.64 times higher (95% CI: 1.33, 3.98) in those with cognitive impairment compared to those with normal cognitive function. Participants in the highest TyG quartile had a multivariable-adjusted odds ratio (OR) of 1.61 (95% CI: 1.10, 2.35) for depression compared to those in the lowest quartile. Similar results were observed across different gender, age groups, and baseline comorbidities.
Conclusion
Our findings suggest that higher TyG index and cognitive impairment (including deficits in learning and memory, executive function, and attention/processing speed) are associated with a greater likelihood of depressive symptoms in older adults.
Childhood-Onset Ocular Mucous Membrane Pemphigoid Presenting with Peripheral Ulcerative Keratitis: A Case Report and Review of the Literature
Authors: Ramos-Dávila Eugenia M. , Ruiz-Lozano Raul E. , Rodriguez-Garcia Alejandro , Alvarez-Guzman Carlos
Published: June 2024

Purpose
The purpose of this study was to describe the case of a pediatric patient diagnosed with mucous membrane pemphigoid (MMP) with exclusive ocular involvement presenting at diagnosis with peripheral ulcerative keratitis and provide a review of the literature.
Methods
A 12-year-old girl presented with cicatricial conjunctivitis and peripheral ulcerative keratitis (PUK). A conjunctival biopsy and direct immunofluorescence revealed linear deposits of IgG, IgM, and C3 at the basement membrane zone, confirming a diagnosis of ocular MMP.
Results
The patient was initially treated with dapsone 25 mg/day and prednisone 40 mg/day along with topical treatment including cyclosporine 0.05%, loteprednol etabonate 0.05%, and sodium hyaluronate 0.15% and trehalose 3%. Inflammation persisted as an increase in the extension of symblepharon was documented. Subsequently, dapsone was switched to oral methotrexate 15 mg/week and prednisone was successfully tapered to 5 mg/day. After three years of follow-up, disease activity remained quiescent.
Conclusions
Pediatric mucous membrane pemphigoid with ocular involvement is a rare condition of which few reports have been published, resulting in scarce information regarding its clinical course and response to treatment. We report the first case observed in a Hispanic patient, opening with peripheral ulcerative keratitis, and responding successfully to methotrexate.
Modeling and investigation on dynamic behaviors of ball screw feed system with bolt looseness
Authors: Liu Zhendong , Li Changyou , wang gongdong , xu mengtao , zhang hongzhuang , Li zhenyuan , Miao Hui , Wang Chen
Published: June 2024

In this study, a more comprehensive multi-degree-of-freedom nonlinear dynamic model of ball screw feed system is presented. The relationship between bolt preload and contact force of the interface force is established. A new pedestal force model considering bolt looseness and inclination of contact surface is established. Based on the spatial position between pedestal and foundation, the modeling method of contact force of interface is proposed. The influence of bolt preload and bolt looseness on the dynamics of the feed system are investigated. A series of experiments are conducted to validated the proposed modeling method. The fractal parameters are obtained by the measurement of surface morphology. The results show that the increased preload have impacts on the vibration response and reduce the positioning accuracy of the system in specific frequency. Moreover, the proposed model is compared with traditional method proposed by previous study.
A multi-centric, single blinded, randomized, parallel group study to evaluate the effectiveness of nasoalveolar moulding treatment in non-syndromic patients with complete unilateral cleft lip, alveolus, and palate (NAMUC study). A study protocol for a randomized controlled trial.
Authors: Thiruvenkatachari Badri , Bonanthaya Krishnamurthy , Kuijpers-Jagtman Anne Marie , Sandler Jonathan , Powar Rajesh Shankar , Hussain Syed Altaf , B Subramanian , Bhola Nitin , Bhat Hari Kishore , Ramachandra Varun , Jayakumar Sylvia , Batra Puneet , Chakkaravarthi Subhiksha , V Thailavathy , Prathap Manoj , Elumalai Thulasiram , Nambiar Karthika , Vijayakumar Charanya , Mahajan Ravi Kumar , Sood Sundereshwer Chander , Kahlon SukhdeepSingh , Bijapur Shruti , Kamble Ranjit Haridas , M Keluskar K , Nigalkar Amit , Khan Faizan Ahmed , Das Devika , Srid Swetha , Buch Adrija , Kumar Shuba , Mohanraj Rani , Listl Stefan , Chopra Samiksha , Jadhav Vikranth , Arora Anika , Valiya Chintan , Pattamata Madhuri
Published: June 2024

Background: Cleft lip and palate (CLP) are among the most common congenital anomaly that affects up to 33,000 newborns in India every year. Nasoalveolar moulding (NAM) is a non-surgical treatment performed between 0 and 6 months of age to reduce the cleft and improve the nasal aesthetics prior to lip surgery. The NAM treatment has been a controversial treatment option with 51% of the cleft teams in Europe, 37% of teams in the US and 25 of cleft teams in India adopting this methodology. This treatment adds to the already existing high burden of care for these patients. Furthermore, the supporting evidence for this technique is limited with no high-quality long term clinical trials available on the effectiveness of this treatment.
Method: The NAMUC study is an investigator initiated, multi-center, single blinded randomized controlled trial with a parallel group design. The study will compare the effectiveness of NAM treatment provided prior to lip surgery against no treatment control group in 274 patients with non syndromic unilateral complete cleft lip and palate. The primary endpoint of the trial is the nasolabial aesthetics measured using Asher McDade index at 5 years of age. The secondary outcomes include dentofacial development, speech, hearing, cost effectiveness, quality of life, patient perception, feeding and intangible benefits. Randomization will be carried out via central online system and stratified based on cleft width, birth weight and clinical trial site.
Discussion: We expect the results from this study on the effectiveness of treatment with NAM appliance in the long term along with the cost effectiveness evaluation can eliminate the dilemma and differences in clinical care across the globe.
Trial Registration number: CTRI/2022/11/047426 (Clinical Trials Registry India) CTR India does not pick up on Google search with just the trial number. The following steps have to be carried out to pick up. How to search: (https://ctri.nic.in/Clinicaltrials/advsearch.php - use the search boxes by entering the following details: Interventional trial>November 2022>NAMUC)
Exercise Enhances Cardiomyocytic Mitochondrial Homeostasis to Alleviate Left Ventricular Dysfunction in Pressure Overload-Induced Remodelling
Authors: Ma Zhichao , Cen Yanling , Xun Weiwei , Mou Caiying , Yu Junwen , Hu Yarui , Liu Chen , Sun Jun , Bi Rui , Qiu Yanli , Ding Mingchao , Jin Li
Published: June 2024

Background: This study aims to explore how exercise enhances mitochondrial regulation and mitigates pathological cardiac hypertrophy.
Methods: Rat groups were assigned as CN, sham, SC, and SE. A bioinformatics analysis was conducted to uncover the underlying mechanisms.H9C2 cells were divided into: CON, Ang II, sh-GFP+Ang II, sh-ndufb10+Ang II, Ad-GFP+Ang II, and Ad-ndufb10+Ang II. Mitochondrial function was measured. mRNA and protein expression were assessed by qPCR or western blot analysis respectively.
Results: In the SC group, a significant increase was observed in cardiomyocyte diameter, function, autophagy, and apoptosis. After 8 weeks of swimming exercise, there was a substantial reduction in cardiomyocyte diameter, an improvement in cardiac function, a mitigation of mitochondrial fission and autophagy, and cardiomyocyte. Ndufb10 was markedly enriched in oxidative phosphorylation and downregulated in the SC group, while it was upregulated in the SE group. In the sh-ndufb10 group, mitochondrial fusion was suppressed; fission and autophagy were further facilitated; mitochondrial membrane potential, mPTP, and ROS levels increased; and TUNEL and apoptosis-related proteins showed significant upregulation. Overexpression of ndufb10 reversed pathological hypertrophy, mitochondrial autophagy, mitochondrial dysfunction, and cardiomyocyte in vitro.
Conclusions: Swimming exercise improves mitochondrial abnormalities and reduces cardiomyocyte through regulation of the ndufb10 in left ventricular hypertrophy.
Post-traumatic stress symptoms in interpreters assisting in psychotherapy- one-year follow-up
Authors: Herold Monja Lucia , Müller Lauritz Rudolf Floribert , Unterhitzenberger Johanna , Rosner Rita
Published: June 2024

Background: Interpreters are an important support in psychotherapy with patients who do not speak the national language. In the primarily qualitative literature, post-traumatic stress symptoms (PTSS) in interpreters are frequently mentioned, especially when translating traumatic content in trauma-focused psychotherapy. Possible risk and protective factors identified in research are the measurement occasion an attitude supporting psychotherapy, knowledge about post-traumatic stress and trauma-focused therapy, the working experience of the interpreters in years, Involvement of Interpreters in Trauma-Therapy, own refugee experience and any kind of qualificationbefore the training.
Method: A total of 134 interpreters registered for a workshop on translation in the context of trauma-focused cognitive behavioral therapy. Questionnaires were completed via Qualtrics before and after the workshop, and at 6 and 12 months. The Post Traumatic Stress Disorder (PTSD) Checklist for DSM-5 (PCL-5) was used to assess the interpreters’ PTSS. Hierarchical linear models were calculated with the R package lme4 to examine the development of PTSS symptoms over time and possible influencing factors.
Results: The interpreters’ PTSS did not change significantly over the one-year period. Attitude and knowledge had a positive influence on PTSS, while participation in trauma therapy had a negative influence on PTSS.
Discussion: Results show that the interpreters’ PTSS remained stable over the course of one year. However, translating in psychotherapy during this period represents a risk factor for interpreters´ PTSS. Further research on possible risk and protective factors for interpreters’ PTSS is necessary. One of the limitations of the present study is that it is a convenient and uncontrolled sample.
The health care needs and associated factors of breast cancer patients in shanghai, china
Authors: Chen Minxing , Zhu Qing , Qin Qiujun , Song Wenhua , Li Ruijia , Song Jie , Jin Chunlin
Published: June 2024

Background: As the number of breast cancer survivors increases, fatigue, poor physical fitness, and sleep quality issues begin to emerge, and there is a broad range of unmet health care needs.
Objective: To accurately identify and measure the unmet health care needs of breast cancer patients, analyze the impact of sociodemographic factors, clinical characteristics, and other factors on the multiple needs of patients, and identify emerging needs and trends in care in order to provide better health care.
Methods: A cross-sectional study of 6,020 cancer patients in Shanghai, focusing on 2,525 female breast cancer patients, was conducted to investigate their socio-demographic information, financial toxicity grade, physical status, and health care needs, and to explore the relationship among socio-demographic factors, financial toxicity, physical status, and health care service needs through descriptive statistics and multiple linear regression analysis.
Results: The unmet needs of breast cancer patients were concentrated in the areas of health education and social support (1.70 ± 0.85), with the most common needs including information, comorbidity management, sleep guidance, and TCM rehabilitation. Bachelor's degree and above (β=8.06, P<0.001), limited self-care (β=16.29, P=0.01), and moderate financial toxicity (β=14.35, P<0.001) were associated with high levels of unmet medical needs, and tumor secondary/metastasis (β=1.52, P=0.01) was associated with unmet needs for primary medical care, health education, and social support.
Conclusion: The overall health care needs of breast cancer patients are at a low level, and new needs such as comorbidity management, sleep guidance, and Chinese medicine rehabilitation have emerged among patients. In the future, it is necessary to combine multidisciplinary and individual characteristics to provide appropriate health care services.
Development of a predictive classification model and extraction of signature wavelengths for the identification of spoilage in chicken breast fillets during storage using Near Infrared Spectroscopy
Authors: Siddique Aftab , Herron Charles B. , Wu Bet , Melendrez Katherine S.S. , Sabillon Luis J. G. , Garner Laura J. , Durstock Mary , Sanz-Saez Alvaro , Morey Amit
Published: June 2024

Technologies for rapid identification and prediction of food spoilage can be crucial in minimizing food waste and losses, although their efficiency requires further improvement. This study aimed to pinpoint specific near-infrared (NIR) wavelengths that could indicate spoilage in raw chicken breast fillets. In this study, commercial tray-packs of boneless, skinless chicken breast fillets stored in a walk-in cooler at 4˚C were periodically tested every other day until they reached the spoilage state (identified by > 7 log CFU/ml). A portable Hyper spectral spectroscopy device (Field Spec Hi-Res4), with a range of wavelengths of 350–2500 nm, was used to measure reflectance. In addition to hyper-spectral analysis, aerobic plate counts were conducted on the fillets. The data from these counts were then used to train a Back Propagation Neural Network (B.P.N.N.) with specific parameters (250,000 steps, a learning rate of 0.02, and 5 hidden layers) and Linear-Support Vector machines (SVM-Linear) with ten-fold cross-validation technique to categorize spoilage into three stages: baseline microbial count (up to 3 log CFU/ml) (Initiation), propagation (between 3 and 6.9 log CFU/ml), and spoiled (> 7 log CFU/ml). The feature extraction process successfully identified the most representative six signature wavelengths from the whole hyper-spectral profile, which facilitated the classification of different phases of spoilage. The BPNN model demonstrated a high classification accuracy, with 93.7% for baseline counts, 95.2% for the propagation phase, and 98% for the spoiled category. These signature hyperspectral wavelengths hold the potential for developing cost-effective and rapid food spoilage detection systems, particularly for perishable items.
pH modulation for high capacity and long cycle life of aqueous zinc-ion batteries with β-MnO2 /3D graphene-carbon nanotube hybrids as cathode
Authors: Jin Duolong , Dong Xiaoping , Liu Jiankai , Pang Qianran , Xin Shenghai , Yang Liying , Wang Cuibiao
Published: June 2024

With the continuous development of new energy application technology, there is an increasingly urgent need for the safety and affordability of new energy storage products. In recent years, aqueous zinc-ion batteries based on mild aqueous electrolytes have garnered widespread attention as a potential replacement for traditional lithium-ion batteries. However, the limited capacity and low operating voltage of aqueous zinc-ion batteries restrict their widespread application. For this reason, sulfuric acid was added to the electrolyte, which effectively promotes the two-electron conversion of MnO2/Mn2+ during the discharge process. This enhancement results in the high-voltage segment of the batteries' discharge phase offering a higher reversible specific capacity. The results showed that the batteries with 0.1 M H2SO4 added to the electrolyte had a reversible discharge specific capacity of up to 536.07 mAh·g-1 at a current density of 100 mA·g-1. The activated batteries exhibited a reversible specific capacity of 85.11 mAh·g-1 even at a high current density of 1 A·g-1. Furthermore, the capacity retention rate after 1,000 cycles was 88.3%. Moreover, the activation rate of the batteries was faster with the addition of H2SO4, and the average operating potential increased compared to the batteries without H2SO4 in the electrolyte. This provides an effective solution for the practical application of aqueous zinc-ion batteries in power grids.
Political Expression of Academics on Social Media
Authors: Garg Prashant , Fetzer Thiemo
Published: June 2024

Academics have traditionally played a vital role in both the generation and dissemination of knowledge, ideas and narratives. Social media, relative to traditional media, provides for new and more direct ways of science communication. Yet, since not all academics may engage with social media, the sample that does so may have an outsize influence on shaping public perceptions of academia more broadly through at least two channels: the set topics they engage with and through the particular style and tone of communication. This paper describes patterns in academics' expression online found in a newly constructed global dataset covering over 100,000 scholars linking their social media content to academic record. We document large and systematic variation in politically salient academic expression concerning climate action, cultural, and economic concepts. We show that these appear to often diverge from general public opinion in both topic focus and style.