bluuebunny/crossref_metadata_2025 huggingface dataset:
A high cell density perfusion process for MVA virus production: process integration with inline DNA digestion and cost analysis
Authors: Gränicher Gwendal , Babakhani Masoud , Göbel Sven , Jordan Ingo , Marichal-Gallardo Pavel , Genzel Y , Reichl Udo
Published: April 2021

By integrating continuous cell cultures with continuous purification
methods, process yields and product quality attributes were improved
over the last 10 years for recombinant protein production. However, for
the production of viral vectors such as Modified Vaccinia virus Ankara
(MVA), no such studies have been reported although there is an
increasing need to meet the requirements for a rising number of clinical
trials against infectious or neoplastic diseases. Here, we present for
the first time a scalable suspension cell (AGE1.CR.pIX cells)
culture-based perfusion process in bioreactors integrating continuous
virus harvesting through an acoustic settler with semi-continuous
chromatographic purification. This allowed to obtain purified MVA
particles with a space-time yield >600% higher for the
integrated perfusion process (1.05 x 1011 TCID50/Lbioreactor/day)
compared to the integrated batch process. Without further optimization,
purification by membrane-based steric exclusion chromatography resulted
in an overall product recovery of 50.5%. To decrease the level of host
cell DNA prior to chromatography, a novel inline continuous DNA
digestion step was integrated into the process train. A detailed cost
analysis comparing integrated production in batch versus production in
perfusion mode showed that the cost per dose for MVA was reduced by
nearly one third using this intensified small-scale process.
Approaching Inpatient Glycemic Control Using Six Sigma Methodology
Authors: Khthir, MD, CPHQ, CCD Rodhan
Published: April 2021

Process variation affects almost all healthcare processes. Wide fluctuation of blood glucose values is very common in hospitalized patients and may impact the outcome of care in negative way. The purpose of this article is to illustrate how to study the process variation using Six Sigma approach and how to us it teaching healthcare quality.
Challenges in the Current Management of Hepatocellular Carcinoma
Authors: Jogi Soumya , Varanasi Radha , Bantu Sravani S , Saduvala Sudha , Manne Ashish
Published: April 2021

Management of hepatocellular carcinoma (HCC) is complicated. Barcelona Clinic Liver Cancer (BCLC) staging system is widely used in risk stratifying HCC. It is different from anatomic staging (TNM) used in other cancers and is based on the liver function (Child-Pugh Score) and performance status at diagnosis along with tumor characteristics like size/number of primary, vascular invasion, and distant metastasis. Guidelines proposed by various liver societies help the treating physician select first-line therapy, but there are many limitations to them. Lack of reliable biomarkers that give objective information to monitor the response other than alpha-fetoprotein or radiological response is hurting the management strategies. There are no ideal predictors for recurrence and residual microscopic disease, especially after locoregional therapy (LRT) like surgical resection, ablation, transarterial chemoembolization (TACE), transarterial radioembolization (TARE), and stereotactic radiation therapy (SBRT). Also, there is no convincing evidence to use adjunct therapy along with LRT in localized HCC. There is a need to identify the subset of HCC that would benefit from peri-procedural therapy. Recommendations for treating advanced HCC with macrovascular invasion is not uniform across the guidelines. Some propose LRT (TACE and/or TARE) or recommend systemic therapy only like tyrosine-kinase inhibitors (TKI) or Immune-checkpoint inhibitors (ICI). A considerable portion of patients have poor liver function (Child-Pugh Score C) at diagnosis. In this era of medicine, we should give them options other than supportive care, but unfortunately, it is the preferred option. This population needs special attention in trials. In current practice, there only 2-3 classes of drugs available like TKI, ICI, and vascular endothelial growth factor (VEGF) inhibitors. There is a need to explore more classes of liver-friendly drugs in treating HCC, and the enrolment of patients in clinical trials must be advised in the guidelines.
Rare Oral Mucous Extravasation Cyst: Case Report
Authors: Gaouzi Rajae El , Chami Bassima
Published: April 2021

Mucoceles are a benign lesions characterized by an extravasation or retention of mucous in submucosal tissue from minor salivary glands caused most probably by a trauma or habit of lip biting. They usually present as an asymptomatic small superficial swelling, which are knew to occur most commonly on the lower lip, followed by the floor of mouth and in other sites. However, uncommon variants of oral mucoceles sometimes occur. Such lesions may be difficult to diagnose due to their unusual localization and atypical clinical presentation. This paper highlights a rare case of mucocele localized in hard palate in a 63 years old male patient. The lesion was depressed, with a bluish appearance, and it measured 7 mm × 5 mm x 2 mm. Diagnosis is based on clinical characteristics, and confirmed with histological features.
Assessing the Level of Knowledge and Attitude of the Saudi Population in Taif City towards Varicoceles Prevention and Treatment
Authors: Badr Samir Ahmad , Almalki Khaled Abdulrahman , Alhathla Thamer Eid M , Alotaibi Abdulelah Mastour , Turkistani Mohammed Adel , Alghamdi Abdulrahman Abdullah , Albagami Mohammed Qazan
Published: April 2021

Background: Varicocele is a common problem in males that drastically affect their reproductive health. There is some way to reduce or prevent this problem from occurrence. However, the level of knowledge of the general public towards these measures is unclear. Methods: A cross-sectional observational survey study that was carried out in Saudi Arabia using an online self-developed questionnaire that was distributed, via a link to Google form, to the general public. All adult literate citizens and residents in Taif city, Saudi Arabia were eligible for inclusion in this study. Only completed surveys were included in the analysis.
Data were represented in the form of frequencies (number of responders) and valid percentages for categorical variables. ANOVA test was utilized to compare means between different subgroups. All P values < 0.05 were considered statistically significant. Result: A total of 275 participants responded to the survey. The mean score for knowledge was 10.01±4.305, with a minimum score of zero and a maximum score of eighteen. Females showed a significantly higher mean score (13.67±3.114) (p-value = 0.002). Single participants showed significantly higher mean score (10.26±4.176) (p-value= 0.04). Responders with a university degree had a higher average score (10.35±4.257) (p-value=0.002), and participants with a medical background had a higher average score (11.48±3.401) (p-value<0.001). Conclusion: A poor level of knowledge and attitude towards varicocele prevention and treatment were observed in Saudi Arabia. Further studies are required to figure out the level of knowledge and behaviors on a national level, and to explore the reasons behind this poor knowledge about varicocele.
Estrus Behaviour and Reproductive Traits of Pulawska Gilts Associated with Selected Gene Polymorphisms
Authors: Babicz Marek , Pastwa Marcin , Szyndler-Nędza Magdalena , Kozubska-Sobocińska Anna , Danielak-Czech Barbara , Kropiwiec-Domańska Kinga , Skrzypczak Ewa , Ślaska Brygida , Kapusta Damian
Published: April 2021

Searching for the associations between the gene polymorphism and the reproductive traits is essential in defining the genetic native breed specificity, which distinguishes them from the other breeds. The aim of our study was to determine the associations between mutations in the PRL, PRLR, PTGS2, FUT1 genes and sexual and periparturient activity in native Pulawska gilts. The analysis included 72 animals which gave birth to the first litter. Evaluation of the productive value of gilts accounted for indicators of sexual and periparturient activity as well as reproductive traits. The biological material for molecular analyses was obtained from the hair roots of the gilts. The genotype was verified by PCR RFLP analysis. The primers and PCR conditions were determined on the basis of available literature data. Statistically significant differences (P≤0.05) were found at the PRL locus: gilts of AA genotypes (Ins/Ins) at the PRL locus were characterised by longest farrowing duration compared to gilts of AB genotype (P≤0.05). The analysis of PRLR gene showed that gilts of TT genotype revealed a tendency for later occurrence of estrus signs (first and second estrus) and for the markedly longest farrowings (P≤0.05). With regard to PTGS2 and FUT1 loci, no significant differences were found in the parameters of sexual and periparturient activity of the gilts. However, gilts of FUT1 GG genotype gave birth to and reared the largest first litters (P≤0.05). The results of the studies expand the knowledge about the genetic structure and productivity of Pulawska gilts.
Determinants of forest land use decisions among rural farm households in south-western Nigeria
Authors: Adetoye Ayoade Matthew , Adewuyi Samuel Ayodele , Akerele Dare
Published: April 2021

The study examined factors determining forest land use decisions among rural farm households in south-western Nigeria. Primary data on socio-economic and community characteristics as well as land use systems were obtained from 300 farm households using a structured questionnaire through a multistage sampling technique. The study revealed that marital status (P < 0.01), gender (P < 0.01), land tenure security (P < 0.01), dominant crop type (P < 0.05), and preference for tree on farm land (P < 0.01) are factors influencing forest land use decision in either agroforestry, pure cultivation or in both practices. Land use choice proportion estimation shows that 63 % are still willing to retain their existing land use practice (pure cultivation). A total of 32 % are willing to shift completely from their existing land use practice while 4 % of the respondents are willing to practice both “agroforestry and pure cultivation” simultaneously. The study therefore suggests the need for a change in forest land use policy, particularly, with a view influence the pattern of use, limitation on type of crop that can be grown, and compliance to sustainable land use practice. This would go a long way in driving forest land use towards agroforestry – a practice identified as a means of ensuring food security while ensuring safe environment.
Trichoptera (Insecta) of the Javorníky Mts. (Czech Republic)
Authors: Kroča Jiří , Komzák Petr
Published: April 2021

A total of 79 Trichoptera species (43 genera, 16 families) were found in the Javorníky Mts. (Czech Republic), including two Carpathian species, Chaetopteryx polonica Dziedzielewicz, 1889 and Potamophylax carpathicus (Dziedzielewicz, 1912). Two further species, Rhyacophila mocsaryi Klapálek, 1898 and Rhyacophila philopotamoides McLachlan, 1879, have, until recently, only been found in the Carpathian Mts. In addition, eight species that occur infrequently or only locally in the Czech Republic were found, Synagapetus moselyi (Ulmer, 1938), Hydroptila angulata Mosely, 1922, Wormaldia pulla (McLachlan, 1878), Plectrocnemia brevis McLachlan, 1871, Tinodes unicolor (Pictet, 1834), Hydropsyche fulvipes (Curtis, 1834), Beraeamyia hrabei Mayer, 1937 and Ernodes vicinus (McLachlan, 1879). Several of these species are listed in the Red List of threatened invertebrates of the Czech Republic (one as endangered, one vulnerable and seven near threatened).
Bombina variegata (Linnaeus, 1758) in rain pools in the Carpathian Mountains (Slovakia)
Authors: Csanády Alexander , Oboňa Jozef , Duranková Silvia
Published: April 2021

Rain pools (pluviotelmata or puddles) are common, small and non-permanent aquatic ecosystems. Data on the use of rain pools by amphibian taxa in the Carpathian Mountains, especially in Slovakia, are rare. In this study we describe the occurrence of Bombina variegata (Linnaeus, 1758), which may use these small aquatic ecosystems as part of their complex life cycle or where they spend their larval period. The most important hydroperiodic factors affecting the vertebrate fauna were the volume and area of the rain pools, the presence (respectively the absence) of shade, water temperature, biotope structure and the presence of several chemical compounds (NO−
3, GH, KH, pH). This study confirms that micro-habitats, such as rain pools, may play an important role for suitable reproduction sites of B. variegata, as stated by several authors from the different countries and regions of its large distributional range. At the same time, data on the presence or absence of different taxa with important conservation status in the monitored habitat aid in the detection of species.
A New Foot-Mounted Inertial Measurement System in Soccer: Reliability and Comparison to Global Positioning Systems for Velocity Measurements During Team Sport Actions
Authors: Waldron Mark , Harding Jamie , Barrett Steve , Gray Adrian
Published: April 2021

The aims of this study were to i) compare a foot-mounted inertial system (PlayerMaker™) to three commercially available Global Positioning Systems (GPS) for measurement of velocity-based metrics during team sport movements and ii) evaluate the inter-unit reliability of the PlayerMaker™. Twelve soccer players completed a soccer simulation, whilst wearing a PlayerMaker™ and three GPS (GPS#1, #2 and #3). A sub-sample (n = 7) also wore two PlayerMaker™ systems concurrently. The PlayerMaker™ measured higher (p < 0.05) total distance (518 ± 15 m) compared to GPS#1 (488 ± 15 m), GPS#2 (486 ± 15 m), and GPS#3 (501 ± 14 m). This was explained by greater (p < 0.05) distances in the 1.5-3.5 m/s zone (356 ± 24 m vs. 326 ± 26 m vs. 324 ± 18 m vs. 335 ± 24 m) and the 3.51-5.5 m/s zone (64 ± 18 m vs. 35 ± 5 vs. 43 ± 8 m vs. 41 ± 8 m) between the PlayerMaker™, GPS#1, GPS#2 and GPS#3, respectively. The PlayerMaker™ recorded higher (p < 0.05) distances while changing speed. There were no systematic differences (p > 0.05) between the two PlayerMaker™ systems. The PlayerMaker™ is reliable and records higher velocity and distances compared to GPS.
Physiological Exercise and Post‐Exercise Effects of Inverse Sequences of Combined Bench‐Step Aerobics and Resistance Exercise
Authors: Abrantes Catarina , Martins Susana , Pereira Ana , Policarpo Fernando , Machado Isabel , Sousa Nelson
Published: April 2021

The purpose of this study was to compare the effects of using inverse sequences of combined bench-step aerobics and resistance exercise on cardiorespiratory, hemodynamic and perceptual variables during exercise and one-hour post-exercise. The tested sequences were bench-step aerobics immediately before and immediately after resistance exercise. Thirteen apparently healthy and physically active women (age = 21.9 ± 6.1 years, body height = 160 ± 0.1 cm, body mass = 58.8 ± 7.5 kg, estimated fat mass = 17.2 ± 2.0% and estimated maximal oxygen uptake = 37.5 ± 2.6 mL∙kg-1∙min-1) performed a 20-minute bench-step aerobics routine, immediately before (STEP_RES) and after (RES_STEP) resistance exercise. Oxygen uptake and heart rate were continuously measured, systolic and diastolic blood pressure, body temperature and perceived exertion were measured at rest, immediately after each type of exercise and at 15, 30, 45 and 60 min after exercise. When resistance exercise was performed first (RES_STEP), oxygen uptake was higher (23.2 ± 3.9 vs. 20.5 ± 4.8 mL∙kg-1∙min-1), but the heart rate (164.5 ± 9.1 vs. 173.9 ± 11.7 bpm) and body temperature (36.5 ± 0.4 vs. 37.6 ± 0.6 ºC) were lower. In both sequences, the type of exercise performed first was pointed out with a lower perceived exertion or lower perceived intensity. Exercise and 60-min post-exercise blood pressure had a similar response in both sequences, and systolic blood pressure along with diastolic blood pressure were lower than pre-exercise from 30 min until 60 min post-exercise. The results suggest that the sequence affected oxygen uptake and perceived exertion during exercise and that this total workload, despite the sequence, promoted a post-exercise blood pressure decrease in normotensive participants.
Effects of Flywheel Resistance Training on Sport Actions. A Systematic Review and Meta-Analysis
Authors: Raya-González Javier , Prat-Luri Amaya , López-Valenciano Alejandro , Sabido Rafael , Hernández-Davó Jose
Published: April 2021

The purpose of the present meta-analysis was to examine the effect of flywheel resistance training (FRT) on main sport action (i.e., jumping performance, sprinting time and change of direction performance) improvements in athletes and healthy active people. A Boolean search strategy adapted for each of the databases employed was conducted to identify all studies measuring change in sport actions performance after FRT interventions up to July 2019. Outcomes were analysed using an average effect size (D+) and a 95% confidence interval (CI), which was calculated assuming a random-effects model. A total of 9 studies with 283 participants met the inclusion criteria and were selected for the analysis. The mean quality score (PEDro scale) of the articles included in the meta-analysis was 5.67. The meta-analysis showed significant positive effects on jumping performance (SMC 0.65; 95% CI, 0.11-1.19; p = 0.02), sprinting time (SMC 1.33; 95% CI, 0.39-2.28; p < 0.01) and change of direction performance (SMC 1.36; 95% CI, 0.58-2.14; p < 0.01) after FRT interventions compared to control/traditional resistance training groups. The results of the present meta-analysis provide evidence of the usefulness of FRT to improve variables related to sport performance in both athletes and healthy population.
Cardiovascular Imaging Techniques for Detection of Vulnerable Plaques
Authors: Márton Emese , Cernica Daniel , Țolescu Cosmin , Lupșan Andrada , Chițu Monica , Benedek Imre
Published: April 2021

Various cardiovascular imaging techniques were developed for the detection of vulnerable atherosclerotic plaques, hoping to be able to predict a cardiovascular event. Plaque vulnerability results from compound pathophysiological mechanisms that lead to structural and morphological changes in lesions. The aim of this review is to present the most recent techniques for the assessment of vulnerable coronary plaques such as cardiac computed tomography angiography (CCTA), optical coherence tomography, or virtual histology intravascular ultra-sound, based on literature data from the last 3 years. CCTA permits direct visualization of the intravascular lumen, together with characterization of the arterial wall. Recent studies maintain that low-attenuation plaques, spotty calcifications, positive vessel remodeling, and the napkin-ring sign are considered main markers of plaque vulnerability and instability. Emerging analytical techniques, such as machine learning or radiomics, will probably demonstrate useful as an auxiliary diagnostic tool for vulnerable plaque detection. The data from the two imaging techniques together provide useful information, especially in patients undergoing a PCI procedure for an acute coronary syndrome. Invasive and noninvasive imaging techniques are able to deliver a large amount of scientific data to assess vulnerable coronary atheromatous plaques. Recent studies demonstrated that information defined by the two techniques is complementary, and using both methods is essential for adequate diagnosis, therapeutic strategy, and prognostic assessment.
Acute Coronary Syndrome and Arrhytmia Induced by SARS-CoV-2 Infection in a Patient with Non-Significant LAD Lesion. A Case Report
Authors: Oltean Péter Balázs , Kovács István , Hodas Roxana , Rat Nora , Benedek Theodora
Published: April 2021

Background: Coronavirus disease 2019 (COVID-19) has emerged as a pandemic and public health crisis of an unprecedent effect. Clinical studies reported an association between COVID-19 and cardiovascular disease, whereas COVID-19 itself can induce myocardial injury, arrhythmia, acute coronary syndrome, and venous thromboembolism.

Case summary: A patient diagnosed via screening coronary computed tomography angiography with non-obstructive coronary artery disease was hospitalized with non-ST elevation myocardial infarction and atrial flutter during a severe respiratory infection episode with SARS-CoV-2. After recovery from the infectious episode, fractional flow reserve-guided elective percutaneous coronary intervention with drug-eluting stent was performed.

Conclusions: COVID-19 intercurrence in a cardiovascular patient with nonobstructive coronary artery disease triggered coronary plaque vulnerabilization with subsequent development of an acute coronary syndrome. SARS-CoV-2 proved to be involved via direct viral tissue involvement and concomitant mechanisms derived from systemic illness in the development of a severe supraventricular arrhythmic event.
Benefits of Energy Storage Systems for Small-Scale Wind Farm Development in Latvia
Authors: Groza E. , Balodis M. , Gulbis K. , Dirba J.
Published: April 2021

The paper covers the main aspects and restrictions on siting small-scale wind farms in Latvia and benefits of using energy storage systems with small-scale wind farms. The restrictions of siting have been analysed. Grid connection restrictions are addressed as the main issues for small-scale wind farm development in Latvia. Two small-scale wind farm models with similar properties have been made and analysed within the framework of the research. The paper proposes the idea for maximising the production of small-scale wind farm in a small area site with high wind potential.
Liquefied Natural Gas Infrastructure and Prospects for the Use of LNG in the Baltic States and Finland
Authors: Savickis J. , Zemite L. , Jansons L. , Zeltins N. , Bode I. , Ansone A. , Selickis A. , Broks A. , Koposovs A.
Published: April 2021

In the early 2010s, only 23 countries had access to the liquefied natural gas (hereinafter – LNG). Import terminals, despite attractive short-term economics, took long time to build, and rigid supply contracts made truly global use of LNG rather complicated. Concerns about geo-political risks also stunted demand growth from existing supply sources, even when new LNG export routes and sources became available.

Current natural gas market is very different, both in terms of market participants and accessibility and diversity of services. In 2019, the number of LNG importing countries reached 43. Rising competition among suppliers and increasing liquidity of markets themselves created favourable conditions to diversify contract duration, size, and flexibility. In addition, development of floating storage and regasification unit (hereinafter – FSRU) technology provided LNG suppliers with a quick response option to sudden demand fluctuations in regional and local natural gas markets [1].

Moreover, LNG is one of the major options not only for bringing the natural gas to regions where its pipeline supply infrastructure is historically absent, limited or underdeveloped, but also for diversification of the natural gas supply routes and sources in regions with sufficient state of pipeline delivery possibilities. And it concerns smaller natural gas markets, like the Baltic States and Finland as well. Accordingly, prospects for use of LNG there in both mid and long-term perspective must be carefully evaluated, especially in regards to emerging bunkering business in the Baltic Sea aquatory and energy transition in Finland, replacing coal base-load generation with other, more sustainable and environmentally friendly alternatives.
FRASKYV – metode og verktøy i dansekunstneriske prosesser
Authors: Nesse Caroline Wahlström , Myhre Camilla
Published: April 2021

In our work as dance artists we have for many years worked at guiding creative and artistic processes based on body and movement. We have developed didactic models that can be put to use in encounters with both children and young people, as well as students and professional dancers. Our work is based on guiding or coaching starting from the individual’s viewpoint. In these processes it is the individual expression that is being cultivated, always in an artistic context. The work is founded in a phenomenological view of body and movement, with the lived, experienced body as a central concept.

An important part of our work has been about developing models and tools where physical principles, understanding of shape, expression, space and composition, can be seen in relation to the individual’s creative and artistic process. Through this a need has arisen to find new words and terms that can explain artistic processes in a more overall way and where the development of bodily knowledge is not separated from the artistic processes.

In this context we have found a new word, “fraskyv”, that could be understood as the opposite of gravitation, like a push-off, some kind of upward pull, a spring, momentum, or maybe as a shift of weight, transfer or a change in a wider sense. The point has been to find a word that can contain both technical and creative elements, and this word “fraskyv” is the starting point for this article.
Kunsten at pille et løg:
Authors: Daugaard Kasper , Ørum Amalie
Published: April 2021

To peel an onion, to grate a carrot, and to set a table, each has its own choreographic recipe. Culinary art/ cookery is choreographed everyday life, and cooking is a dance everyone knows.

The Art of Peeling an Onion is based on the dance piece Gæst (Guest), choreographed by Kasper Daugaard. The piece is for five dancers, a female soloist and four choir dancers, and originates entirely from culinary actions. The purpose of the article is not to maintain theory and practice as two separate entities, but to show how they supply each other and offer each other content. We aim to create a balanced understanding of the relationship between the creative process, the audience experience, and the aesthetic theory related to both the content and the outcome of artistic work. We view theory and practice hand in hand, because we have strived to put into words that which can be experienced, to verbalise the spectator’s experiences, the physical as well as reflexive, with the ambition of formulating a quite tangible experience-based aesthetics.
Et fast greb i rebet – om Claras levede erfaringer som nycirkus artistelev
Authors: Degerbøl Stine
Published: April 2021

The article concerns the lived experiences of Clara practicing to become a contemporary circus artist. Clara’s narratives reflect contemporary circus as a movement pedagogical practice in relation to theories about aesthetic learning and in relation to the aims of a circus performer education in Copenhagen, Denmark. Furthermore her narratives provide a discussion of educational settings on the fringe of ordinary youth education. Firstly contemporary circus is presented as a counterculture to the traditional circus and secondly it describes how the development of contemporary circus as an art form influenced the establishment of contemporary circus schools. Body phenomenology and narrativity are the main theoretical and methodological inspirations for reflections about aesthetic learning processes taking point of departure in Clara as a case.
The Embodied Teaching Moment:
Authors: Østern Tone Pernille
Published: April 2021

In this article the author dialogues with two contemporary dance teachers about how the practical-pedagogical knowledge of the teacher is embodied. The focus is on how the dance teacher functions as a lived body (Merleau-Ponty, 1962/2002) while in the teaching moment. The analysis of the empirical material shows that there is a continuous exchange between the dance teachers’ bodily experiences, inner dialogue and teaching choices while teaching. It is argued that its is not wrong to say that all these two dance teachers do as teachers is bodily grounded. The ways in which the practical-pedagogical knowledge of the two contemporary dance teachers is embodied can be summarized as a bodily listening, bodily tutoring and bodily ambiguity surrounded by constantly and rapidly changing body tunes throughout their teaching. These larger themes are divided into nuances which are presented and discussed in the article. The study is also a method study in how to study in and with the arts. The research process is understood as an iterative cyclic web (Smith and Dean 2009), where practice and theory take place in every sub-process of the study. Outcomes of the study are both theorisation as this article and artwork in the form of choreographies by the two dance teachers. These can be seen at
https://vimeo.com/40433953
(Mari) and
https://vimeo.com/40075211
(Ingeborg).
Effect of High-Velocity Low-Amplitude Thrust Manipulation of Upper Cervical Spine on Pulmonary Function Test and Headache Disability Index in Patients with Migraine Headache
Authors: Punia Sonu , Malik Manoj , Jangra Shalu , Kaur Jaspreet , Singh Varun
Published: April 2021

Introduction. Migraine is a common debilitating disorder of neurovascular origin which affects younger adults, especially women.

Material and Methods. It was an experimental study design. A convenience type of sampling was used for recruitment of the subjects. A total of 21 participants diagnosed with migraine (6 males and 15 females) fulfilling the inclusion criteria were taken for this study and assigned to one of the two groups (experimental or control group). PFT measured with PFT apparatus (Spirolab 111, Serial No. A23-053 13974) and HDI score were calculated before the start of the intervention and after the intervention. Afterwards, PFT was performed by each participant followed by HVLA thrust manipulations to the migraine patients and an equal period of rest to the control group.

Results. There are no significant differences between baseline and post-intervention outcome variables and in mean changes between the two groups. One-way ANOVA was used to analyze the change in HDI score which was calculated three times (pre- prior to intervention, post- after the intervention and 1 month after the intervention). The experimental group showed a significant reduction in the score after the manipulation. It was found that FVC and PEF were positively correlated to FEV1, and FVC was also positively correlated to PEF.

Conclusions. The findings of the study revealed that high-velocity thrust manipulations of upper cervical spine were not effective in improving pulmonary functions of migraine patients although it was found effective in improving subjective symptoms of the patients evaluated through HDI.
Adrenal vein sampling for primary aldosteronism: a 15-year national referral center experience
Authors: Kocjan Tomaz , Jensterle Mojca , Vidmar Gaj , Vrckovnik Rok , Berden Pavel , Stankovic Milenko
Published: April 2021

Background

Adrenal vein sampling (AVS) is essential for diagnostics of primary aldosteronism, distinguishing unilateral from bilateral disease and determining treatment options. We reviewed the performance of AVS for primary aldosteronism at our center during first 15 years, comparing the initial period to the period after the introduction of a dedicated radiologist. Additionally, AVS outcomes were checked against CT findings and the proportion of operated patients with proven unilateral disease was estimated.

Patients and methods

A retrospective cross-sectional study conducted at the national endocrine referral center included all patients with primary aldosteronism who underwent AVS after its introduction in 2004 until the end of 2018. AVS was performed sequentially during Synacthen infusion. When the ratio of cortisol concentrations from adrenal vein and inferior vena cava was at least 5, AVS was considered successful.

Results

Data from 235 patients were examined (168 men; age 32–73, median 56 years; BMI 18–48, median 30.4 kg/ m2). Average number of annual AVS procedures increased from 7 in the 2004–2011 period to 29 in the 2012–2018 period (p < 0.001). AVS had to be repeated in 10% of procedures; it was successful in 77% of procedures and 86% of patients. The proportion of patients with successful AVS (92% in 2012–2018 vs. 66% in 2004–2011, p < 0.001) and of successful AVS procedures (82% vs. 61%, p < 0.001) was statistically significantly higher in the recent period.

Conclusions

Number of AVS procedures and success rate at our center increased over time. Introduction of a dedicated radiologist and technical advance expanded and improved the AVS practice.
ИЗРАДА ПРЕТХОДНИХ АСФАЛТНИХ МЕШАВИНА ЗА ПРИМЕНУ У ГРАДСКИМ УСЛОВИМА
Authors: Ђурђевић Марко , Шешлија Mилош
Published: April 2021

У раду су дате  везе између асфатлних мешавина АБ 16 и БNS 22 са и без полимера. Описана је  комплетна процедура  пројектовања претхоног састава асфалтних мешавина и упоређивање графика истих (стабилност, течење, шупљине испуњене везивом, укупне шупљине). Афалтне мешавине са полимер модификованим битуменом због својих својстава има све већу примену код тешког саобраћајног оптерећења, односно деловима пута  где је велики обим саобраћаја.
PROJEKAT ARMIRANOBETONSKE VIŠESPRATNE ZGRADE PREMA EVROPSKIM STANDARDIMA
Authors: Mitrović Dejan
Published: April 2021

U prvom delu rada prikazan je projekat armiranobetonske višespratne zgrade Po+Pr+5, a u drugom delu je analiziran uticaj torzionih efekata na seizmički odgovor konstrukcija zgrada prema evropskim standardima.
ПРОЦЕНА СТАЊА И САНАЦИЈА АРМИРАНО-БЕТОНСКЕ КОНСТРУКЦИЈЕ ЗГРАДЕ ЦЕНТРАЛНЕ ЖЕЛЕЗНИЧКЕ ПОСТАВНИЦЕ
Authors: Филиповић Горан
Published: April 2021

У раду је извршена процена стања армирано-бетонске конструкције зграде централне поставнице железничке станице Земун са циљем ње­не санације. На основу детаљне анализе регистрова­них оштећења, предложене су одговарајуће санаци­оне мере, који укључују конструктивну и неконструк­тивну санацију објекта. Како је један од главних узрока оштећења објекта неадекватно одводњавање кровова, у раду је детаљније описан Плувиа Геберит систем кишне канализације, као једна од могућности за решење тог проблема.
PROCENA STANJA, ENERGETSKA SANACIJA I DOGRADNJA ZELENOG KROVA UPRAVNE ZGRADE KOMPANIJE VEGA D.O.O. U VALJEVU
Authors: Tomić Uroš
Published: April 2021

Rad se sastoji iz dve međusobno neza­visne celine. Prvi deo rada predstavlja teorijsko istraži­vački deo sa temom „Pasivne kuće-zgrade“, gde je opisan sam pojam pasivne kuće, principi primene, najbitnije osobine, sistem projektovanja, veza sa ekonomijom. U drugom delu rada izvršen je vizuelni makroskopski pregled objekta, sa ciljem utvrđivanja postojećeg stanja. Za objekat je urađen proračun energetske efikasnosti. Na osnovu ovog proračuna i vizuelnog pregleda konstrukcije, date su sanacione mere koje povećavaju trajnost objekta, energetsku efikasnost, kao i njegovu usaglašenost sa Pravilnikom o energetskoj efikasnosti.
АНАЛИЗА ПРОЈЕКТОВАЊА БИЦИКЛИСТИЧКЕ ИНФРАСТРУКТУРЕ У ЕВРОПИ СА ПРИМЕРОМ ПРОЈЕКТОВАЊА ВАНГРАДСКОГ БИЦИКЛИСТИЧКОГ ПУТА
Authors: Григоров Горан
Published: April 2021

Тема рада јесте анализа позитивних примера планирања, пројектовања, изградње и одржавања бициклистичких инфраструктура. Две водеће земље, што се тиче бициклистичке инфраструктуре, Холандија и Данска представљају управо то, угледне примере како се може и мора. Србија са свим својим лепотама има потенцијал да развија бициклистичку инфраструктуру како у градовима тако и ван њих спајајући села, насеља и градове. Поред анализа, приказан је и процес пројектовања бициклистичких површина који мора да испуни основне захтеве бициклистичке инфраструктуре, безбедност, директност, целовитост, привлачност и удобност. Пројектовање и изградња бициклистичких површина, не разликује се у многоме са пројектовањем и изградњом путева, те можемо рећи да исто важи и за једне и за друге објекте, а то су фазе кроз које се ове радње одвијају, припремни радови, истражни радови и израда радних подлога за пројектовање, пројектовање бициклистичких површина и извођење радова на изградњи бициклистичких површина.
УПРАВЉАЊЕ РИЗИЦИМА У ПОЧЕТНИМ ФАЗАМА МАЛИХ ИНФРАСТРУКТУРНИХ ПРОЈЕКАТА
Authors: Суботић Бојана , Мученски Владимир
Published: April 2021

Један од основних елемената управљања пројектима јесте управљање ризиком пројекта, узимајући у обзир да ризици могу негативно да утичу на успешност реализације пројекта тако што неће бити остварен у задатом временском року, са одређеним квалитетом или у планираном буџету. Инфраструктурни пројекти у Србији врше се на основу захтева и услова инвеститора па је веома важно остварити квалитетно управљање пројек­том, с обзиром да се ради о трошењу јавних финан­сијских средстава и о објектима који имају значајну улогу у развоју града, животне средине и друштва.
UTVRĐIVANjE UTICAJA PARKIRANjA NA TROŠKOVE VOZILA NA RASKRSNICAMA U NOVOM SADU
Authors: Krajinović Dušan
Published: April 2021

Analizom uticaja parkiranja na tokove u krajnjoj desnoj saobraćajnoj traci izabranih bulevara u Novom Sadu, koji po smeru imaju više od jedne saobra­ćajne trake za kretanje vozila, utvrđene su vrednosti izgubljenog vremena za vozila u krajnjoj desnoj traci i napravljen je troškovni model za saobraćajnice na kojima postoji i na kojima ne postoji parkiranje. Vršeno je poređenje dobijenih rezultata sa onim što je  predviđeno po HCM-u i dat je uporedni prikaz istih.
ВИЗИЈЕ РАЗВОЈА ЛАНАЦА СНАБДЕВАЊА СА АСПЕКТА ДИГИТАЛНЕ ТРАНСФОРМАЦИЈЕ
Authors: Јасика Никола
Published: April 2021

У оквиру рада анализирају се могући правци развоја ланаца снабдевања са аспекта дигиталних трансформација у будућности. Први део рада односи се на теоријске поставке и истраживачке студије које се баве визијама развоја, док се у другом делу предствља могућа методологија за процену развоја логистике у Републици Србији која се базира на Делфи техници као методи квалитативних предвиђања.
UPOREĐIVANJE KVALITETA ŠTAMPE NA OTISCIMA DOBIJENIH GRAFIČKIM SISTEMIMA XEROX DOCUCOLOR 252 I XEROX COLOR 1000
Authors: Radatović Gabriel , Kašiković Nemanja , Milošević Rastko
Published: April 2021

U radu su prikazana istraživanja kvaliteta otisaka dobijenih grafičkim sistemima Xerox DocuColor® 252 i Xerox® Color 1000. Merene su vrednosti optičke gustine, spektralne krive kao i CIELab vrednosti za uzorke štampane na podlogama različitih površinskih masa (150 g/m², 200 g/m², 300 g/m²). Detaljnom analizom izmerenih i izračunatih vrednosti, došlo se do zaključaka da je razlika u boji a samim tim i kvalitetu očigledna.
KRITIČKA ANALIZA FOTOREALISTIČNIH I NEFOTOREALISTIČNIH VIZUELIZACIJA
Authors: Prčić Tatjana
Published: April 2021

Istraživanje se bazira na uporednim analizama fotorealističnih i nefotorealističnih vizueli­zacija i definisanju njihovih prednosti i mana. Cilj istraži­vanja je da se ustanovi koji je vid vizuelne prezentacije pogodniji za određene vrste projekata, unapređenje projektantskog procesa, stvaranje odgovarajuće atmo­sfere te isticanje karaktera ambijenta.
TURISTIČKI KOMPLEKS „KARAŠ“ U JASENOVU
Authors: Motorov Jelena
Published: April 2021

Tema rada jeste preuređenje prostora na obali reke Karaš u Jasenovu i njegovo pretvaranje u turistički kompleks. Cilj rada jeste prezentovanje vred­nosti sela i reke koja pored njega prolazi i njihov razvoj uz očuvanje istorije, sa mogućom budućom zaštitom.
STUDIJA PROŠIRENJA PROSTORNIH KAPACITETA ZA VISOKO OBRAZOVANJE U SUBOTICI
Authors: Andrić Filip
Published: April 2021

Tema ovog rada je istraživanje proširenja prostornih kapaciteta za visoko obrazovanje u Subotici.
PRISTUPAČNOST JAVNIH PROSTORA NA PRIMERU UNIVERZITETSKOG KAMPUSA U NOVOM SADU
Authors: Stanić Sara , Vukajlov Ljiljana
Published: April 2021

Pristupačni javni prostori predstav­ljaju osovinu stvaranja zdravog društvenog sistema. Pri­menom principa univerzalnog dizajna na javnim površi­nama ostvaruje se integracija svih grupa građana u društvo i na taj način se izbegava diskriminacija istih. Predmet istraživanja smešten je u kontekst savremenog čoveka i promena koje su se događale u svim aspektima života ostavljajući značajan uticaj na svakodnevno funkci­onisanje stanovnika. Rad se fokusira na adaptaciju urba­nističkih elemenata obuhvatajući različite potrebe, mo­gućnosti i navike modernog čoveka, u cilju obezbeđivanja uslova za stvaranje inkluzivnog društva bez diskrimi­nacija.
REVITALIZACIJA I REŠENJE ENTERIJERA OBJEKTA AUTO-REMONTNOG PREDUZEĆA „AUTOKOMANDA“ U BEOGRADU
Authors: Jončić Staša
Published: April 2021

Ovaj rad ima za cilj definisanje metoda revitalizacije napuštenih objekata sa akcentom na industrijsko nasleđe. Odabirom konkretne lokacije napušetne fabrike prikazana je metoda prenamene objekta i adaptacije u skladu sa novim programom. Prikazan je dizajn novog enterijera koji kombinuje vrednosti industrijskog nasleđa sa savremenim pristupom u oblikovanju poslovnih prostora. Primenjna metoda analizirana je na napuštenom objektu Auto-remontnog preduzeća „Autokomanda“ i Beogradu.
VREDNOVANJE PRIKAZA ENTERIJERSKIH SCENA PUTEM MOBILNIH UREĐAJA
Authors: Veselinović Nikola , Jovanović Marko
Published: April 2021

Cilj istraživanja jeste da se ispita relevantnost hedseta u koji se integriše mobilni uređaj po pitanju prikazivanja enterijerskih scena. Metode kojima će ovo istraživanje biti sprovedeno je direktnim poređenjem i upoređivanjem rezultata dobijenih prikazivanjem scena na hedsetu, mobilnim uređajima i računaru. Rezultati su takvi da su scene na sva tri načina uspešno prikazane i realizovane. Zaključak je da svaki od načina ima određene prednosti i mane, ali kako je cilj da se ispita relevantsnost hedseta, može se ređi da su rezultati zadovoljavajući i da je ovaj način prikazivanja scena itekako relevantan.
PRIMENA GRIDŠEL KONSTRUKCIJE NA PROJEKTU BOTANIČKE BAŠTE U NOVOM SADU
Authors: Novaković Nela
Published: April 2021

Tema ovog rada, bavi se moguć­nostima primene gridšel konstrukcija pri projektovanju botaničke bašte u Novo Sadu, kao i načina generisanja takvih modela digitalnim tehnikama.
KREATIVAN HUB U KOMPLEKSU ELEKTROLUXA- PROJEKTOVANJE ENTERIJERA
Authors: Jović Nemanja
Published: April 2021

Revitalizacijom kompleksa u HUB, dobili smo različite prostore koje direktno komuniciraju sa javnošću i publikom, kroz rad galerija, ateljea, coworkinga i drugih programskih prostora. Sam cilj projekta jeste funkcionalno rešenje kompleksa, stvaranje manjih ambijenta u kompleksu i na kraju sam dizajn prostora (materijali, osvetljenje). Reanimacijom prostora teži se stvaranju novog ambijenta koji će biti prijatan, kvalitetan prostor.
Possible ore-controlling structures for the Woxi Au/Sb/W deposit in Tanghuping Mining Section, Hunan Province, South China
Authors: Wang Xi , Godin Laurent , Yang Jinjun , Zou Kai
Published: April 2021

The Woxi Mining District in Hunan Province, South China, hosts numerous high tonnage gold, stibnite, and tungsten strata-bound deposits. Our research focuses on the geological characteristics of the Tanghuping and Xintianwan faults in the Tanghuping Mining Section, within the Woxi Mining District. The Woxi Mining District exposes mainly slate, with interbedded quartz sandstone and clastic rocks, cut by three faults: the Tanghuping, Xintianwan, and Woxi faults. We test the hypothesis that the mineralization in this district is structurally controlled, related to motion along these faults. While the presence of Tanghuping and Xintianwan faults in the Tanghuping Mining Section has not been confirmed, the proposed faults are interpreted to be intimately related to mineralization. The results of previous field works have corroborated the location of the Tanghuping and Xintianwan faults and suggest that zones of high strain coincide with these faults. However, recent core logging data do not show evidence of fracture zones at the expected depth. It is therefore still unclear if the high strain is related to the presence of the faults or if it is the result of fold-related interlayer flexural slip. Microstructural analysis is used to further characterize strain-induced recrystallization textures and sense of shear near and within the interpreted fault zones. Understanding this relationship is important to assist exploration in detecting ore systems on a regional scale and identify the most profitable areas.
The Pieces We Leave Behind: A Tale of Two Artists and a Desk
Authors: Mostert Hannah
Published: April 2021

How do objects gather value and bear the weight of history? This research project addresses this question through research into an old wooden desk stored in the corner of an office at Queen’s University. It has six drawers coloured with a black cherry stain and decorative wooden handles. Adhered onto the desktop surface is a thin overlay of dark leather, to which is affixed a brass plaque that reads, "This desk was used by two famous Canadian artists, J.W. Beatty (1869-1941) and A.Y. Jackson (1882-1974). It was presented to Queen's University in 1980 by Dr. Naomi Jackson Groves, niece of A.Y. Jackson." J.W. Beatty and A.Y. Jackson were influential Canadian painters, whose stylistic focus on Canadian landscapes underpinned the formation of the Group of Seven; the desk was a non-sentient observer of their contributions to Canadian art and art history until 1968, when the desk left Jackson’s possession. Beyond the desk's immediate story, there is a larger research question: "how does the social biography of an object reveal the dynamics of its meaning, affect its value as a physical object, increase its significance in the art world, and determine where it is best preserved?" Using information uncovered during the summer of 2019, this presentation will reveal the importance of the desk’s provenance in relation to the stories of two influential Canadian artists, as well as share the process of investigating the biography of the desk through archival research methods.
Extending Vocal Pedagogy: Extended Vocal Techniques in North American Post-Secondary Music Education
Authors: Romao Vanessa
Published: April 2021

In North America, post-secondary music education is heavily focused on (and limited to) the repertoire and techniques of the Western Art Music canon. Vocal training at these institutions is no exception: vocalists are trained in the bel canto technique whose lineage reaches back to seventeenth-century Italy. This conservatory-based curriculum supports a categorical vocal pedagogy, one that seeks to produce a particular type of singer with a very specific kind of sound. Instead of embracing what each individual singer is capable of, this model focuses on what singers should be capable of from the perspective of repertoire and technical mastery in the operatic tradition. In this paper I will argue that this model risks our losing sight of what the singer has to say in favour of what the composer has to say. Recently there has been discussion and research around a more inclusionary model of vocal pedagogy that would incorporate other techniques alongside bel canto. However, these discussions have been focused on inclusion of musical theatre and belt techniques, with very little discourse on the inclusion of extended vocal techniques. By drawing on the scholarly discourse on the limits and extensions of technical training in post-secondary vocal performance, as well as interviews with several women working in the performance and teaching of extended vocal techniques in Canada, I will explore the potential for extended vocal techniques to contribute to a more inclusive model of vocal pedagogy.