bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular-genetic testing in preoperative diagnosis and choice of surgical tactics in patients with thyroid neoplasms
Authors: Romashchenko Pavel N. , Maistrenko Nicolay A. , Ivanov Andrey M. , Krivolapov Denis S. , Simonova Maria S.
Published: January 2022

The high frequency of the detection of follicular thyroid tumors requires the development of the most effective new methods for their differential diagnosis to early verification of well-differentiated cancer, reduce the number of unjustified surgical interventions, select their rational volume, and improve the treatment results. The use of molecular genetic research methods in preoperative diagnostics and the choice of surgical tactics in patients with the thyroid neoplasms was substantiated. To optimize the algorithm of diagnosis and treatment, a retrospective analysis of the results of examination and surgical treatment of 100 patients with the thyroid neoplasms was carried out, the diagnosis of which was supplemented by the determination of molecular genetic markers in the cellular material of the puncture fine-needle biopsy using a flow fluor-cytometry and polymerase chain reaction. The diagnostic significance of the preoperative determination of the tumor marker Galectin-3, the V600E mutation of the BRAF gene in the puncture material in the detection of thyroid cancer and the choice of the rational surgical tactics was assessed. The prognostic value of the sodium iodide symporter in the development of a thyroid cancer resistance to postoperative radioactive iodine therapy has been established, which makes it possible to substantiate the need to expand the scope of the surgical intervention. The use of an optimized diagnostic and treatment algorithm, considering a new molecular genetic research methods in this category of the patients, contributes to the choice of individualized surgical tactics, depending on the nature of the pathological process.
Unintentional bile duct injuries: prevention and treatment
Authors: Pryadko Andrey S. , Romashchenko Pavel N. , Sedletsky Rostislav R. , Aliev Arsen K. , Yaraliev Vagif M.
Published: January 2022

Presented herein is a rational program of prevention, diagnosis, and the surgical treatment of patients with the unintentional bile duct injuries. Examination results and surgical treatment of 1,117 patients, who underwent laparoscopic cholecystectomy for acute and chronic cholecystitis from 20052020, were studied. The criteria for inclusion in the study were difficult laparoscopic cholecystectomy (181 medical histories) and unintentional bile duct injuries resulting from laparoscopic cholecystectomy (95 patients). Laparoscopic cholecystectomy with a duration of 60 min was considered difficult. A total of 181 (17.7%) medical cases with difficult laparoscopic cholecystectomy and 95 patients with unintentional bile duct injuries were selected for this study. Instrumental studies were performed using X-ray contrast techniques such as: percutaneous fistulography, percutaneous-transhepatic, or intraoperative cholangiography, as well as relaparoscopy, ultrasound, endoscopic retrograde, or magnetic resonance cholangiopancreatography. A program approach to assist the patients with cholelithiasis was developed. Program implementation allows timely prevention and diagnosis of the unintentional bile duct injuries with minimal postoperative complications. The identification of the risk factors for difficult laparoscopic cholecystectomy indicates the need to comply with the preventive measures to prevent unintentional bile duct injuries and dictates the implementation of the surgical intervention by the most experienced surgeons from the second or third-level medical organizations. The rational option of surgical intervention aimed to eliminate the biliary tract injuries based on the following assessment criteria: general somatic condition of the patient, presence of the infectious complications, damage scale, crossed duct diameter, damage mechanism, and damage to the vessel. The right choice of the surgical intervention ensures a reduction in the number of complications and mortality, and quality of life improvement in patients with the unintentional bile duct injuries.
Development of a method for the identification of rs6265 polymorphism in the human brain neurotrophic factor gene
Authors: Kutelev Gennady G. , Krivoruchko Alexander B. , Trandina Alexandra E. , Morozova Natalia E. , Cherkashin Dmitriy V. , Ivanov Andrey M. , Ovchinnikov Dmitrii V. , Glushakov Ruslan I.
Published: January 2022

The analysis and generalization of data from the literature sources characterizing the structural organization, regulation of expression, and functional activity of the neurotrophic factor of the human brain, which is one of the most common regulators of biological processes in the nervous system, is carried out. The results of numerous studies demonstrating the association of the brain-derived neurotrophic factor (BDNF) gene with the pathophysiology of the affective disorders are noted, and its contribution to the development of neuroplasticity is confirmed. The results of the design of a pair of primers and adaptation of the amplification reaction of the BDNF region with a length of 433 nucleotide pairs containing the polymorphic locus RS6265 are presented. Restriction endonuclease was selected. The sequence of primers, their localization, and correlation with the restriction site provided the separation of alternative alleles necessary for the successful identification of this marker. The use of the proposed technique made it possible to uniquely identify the genotype in 38 examined whole blood samples and identify the rare allelic variants. Also, the frequency of polymorphic variants of RS6265 of the BDNF gene was established in all the samples. There was an increase in the proportion of genotypes G/A and A/A of the RS6265 polymorphism of the BDNF gene in the group of examined systematically exposed to extreme factors. Identification of people with a rare A/A genotype of the RS6265 polymorphic locus of the BDNF gene is of a great importance for the monitoring system of long-term potentiation processes leading to the development of neuropsychic pathology. The possibility of implementing this method of genotyping in a typical laboratory using a polymerase chain reaction is proved. The proposed version of the polymerase chain reaction with the subsequent analysis of the polymorphism of the lengths of restriction fragments could be used as a fast, inexpensive, and reliable system for identifying single-nucleotide genetic polymorphisms.
Relationship of creativity and genetic factors in military services in the conditions of the arctic region
Authors: Spivak Irina M. , Lemeshchenko Alexey V. , Agafonov Pavel V. , Khalimov Yuri S. , Zhekalov Andrey N. , Gaiduk Sergey V. , Spivak Dmitry L.
Published: January 2022

The article examines the relationship between the creativity and genetic factors in a serviceman serving in the Arctic region with the special climatic and geographical parameters, a kind of sanitary and epidemiological situation, as well as the complexity of a military labor. A linear correlation analysis of the indicators of a creativity was carried out as one of the most important abilities of the personality, allowing timely response and adaptation to the changing conditions of the external social environment, and the polymorphism of four genes that take an active part in the process of the adaptation to the conditions of the Arctic region: the gene for the serotonin receptor 2A, the gene for angiotensin converting enzyme-1, the gene for neurotrophic factor, as well as the gene for alpha-actinin-3. It was found that the maximum level of verbal and imaginative creativity is observed in carriers of the Val / Val genotype of the neurotrophic factor gene, as well as the RR genotype of the alpha-actinin-3 gene. The carriers of these genotypes are characterized by a high production of neurotrophines that stimulate and support the development of neurons, which may determine the resistance of the central nervous system to unfavorable factors of the external social environment. In addition, the high level of expression of the alpha-actinin-3 protein, characteristic of carriers of the RR genotype of the alpha-actinin-3 gene, promotes accelerated regeneration of skeletal muscles, which may contribute to more optimal adaptation of the body to the harsh conditions of the Arctic region associated with an increased muscle load. When analyzing the angiotensin-converting enzyme gene, the observed patterns with the level of creativity turned out to be less clear, although the servicemen with the DD genotype of this gene showed a minimum level of creativity, which corresponds to the general idea of it as a weaker genotype in terms of the level of general body metabolism and the ability to be active. The characteristics of the creativity in genotypes II and ID of the angiotensin converting enzyme gene were statistically uncertain. The good tightness of the correlation of creativity with the Val/Val genotype of the neurotrophic factor gene, as well as the RR genotype of the alpha-actinin-3 gene, may indicate the advisability of including military personnel planned to be sent to the Arctic region in the examination plan to determine the level of creativity. This will optimize the process of selecting servicemen for service in the Arctic region, and prevent the development of maladjustment disorders, excluding persons with a low adaptive potential.
Excessive hypercorrection after an open wedge high tibial osteotomy: a clinical case
Authors: Prizov Aleksey P. , Zagorodnii Nikolai V. , Nikitin Artem A. , Lazko Fedor L. , Belyak Evgeniy A. , Akhpashev Alexander A. , Lazko Maxim F.
Published: January 2022

Background: Currently, there is a tendency to increasing the proportion of knee joint organ-preserving surgeries. High tibial osteotomy (HTO) has proven itself a good method for the treatment of the knee joint varus deformity in extra-articular deformity cases. The question of the perfect angle of correction, which will not significantly impair the biomechanics of the knee and adjacent joints, remains controversial, as well as the issue of preventing excessive hypercorrection as an osteotomy complication.
Clinical case description: A clinical case of a 59-year-old patient who underwent primary and revision HTOs is analyzed in this article. The patient had a varus deformity of the left lower limb with isolated medial knee osteoarthritis. The patients body mass index (BMI) was 28 kg/m2. The patient complained only of pain and a limited range of motion in the knee joint. According to the arthroscopy and magnetic resonance imaging (MRI) data, there was a cartilage damage classified as Outerbridge 4 stage of the medial compartment. There were no signs of a lateral compartment cartilage damage and patellofemoral joint arthritis. The varus deformity of the knee joint was 10. The patient underwent a medial high tibial open wedge osteotomy. During the preoperative planning, topograms of the lower limb with weight bearing were used. The clinical status before the operation, according to the used scales, was as follows: Knee injury and Osteoarthritis Outcome Score (KOOS) 46 points, Visual Analogue Scale (VAS) 7 cm, American Orthopaedic Foot and Ankle Society (AOFAS) 92 points. 6 months after the initial surgery, the clinical status was as follows: knee joint VAS 1 cm, ankle joint VAS 5 cm, KOOS 88 points, AOFAS 63 points. During the clinical examination and according to the instrumental studies, excessive valgus hypercorrection of 11.2 was noted. Also, the tibial plafond inclination (TPI) and the talar inclination (TI) were significantly increased. 1.5 years after the primary osteotomy, a revision closed wedge osteotomy was performed. The valgus deformity of the knee joint became 3, the axis of the ankle joint changed to the normal values. The clinical and functional results 6 months after the revision osteotomy were the following: KOOS 92 points, AOFAS 99 points, pain in the knee and ankle joint 1 cm by the VAS scale.
Conclusions: The case showed that the careful preoperative planning and the use of additional methods for monitoring the intraoperative correction were important. Excessive valgus hypercorrection promotes good regeneration of the medial compartment cartilage; however, it overloads a lateral compartment and adversely affects the ankle joint and foot.
Markers of brain damage in full-term newborns with intrauterine growth retardation
Authors: Evsyukova Inna I.
Published: January 2022

The increase in the number of newborns with intrauterine growth retardation, who are characterized not only by high perinatal morbidity and mortality, but also by neurodevelopmental disorders in later life, has determined a wide search for diagnostic markers of prenatal hypoxia for a timely objective assessment of brain damage and a justification of neuroprotection methods. This article presents literature data on biomarkers and methods of instrumental diagnosis of brain damage that have received evidence of the effectiveness of their use in early neonatal life of newborns with intrauterine growth retardation. It is emphasized that such biomarkers as S100B, NSE, and BDNF proteins are the most reliable and easy to determine non-invasively. However, for their wide application in clinical practice, it is necessary to establish reference values in umbilical cord blood and urine, while taking into account the gestational age, sex, and method of giving birth, and to unify the use of laboratory analysis systems and diagnostic tests for this purpose. The comparison of biomarker indicators with cerebral oximetry, electroencephalogram and magnetic resonance imaging data will allow for developing new approaches to the treatment of perinatal pathology and, largely, preventing adverse consequences in those born with intrauterine growth retardation.
The Applications of Green Extraction: Production and Quality Characterization of Seed Oils Extracted From Red Pepper (Capsicum Annuum L.) Waste
Authors: ATALAY Ayşe Burcu , İNANÇ Ahmet Levent
Published: January 2022

The study focused on the possibilities of evaluation of red pepper (Capsicum Annuum L.) seeds being a food industry waste. The moisture content (%), the total crude oil and ash content, color, the weight of 1000 seeds, the thickness and diameter of the seeds were characterized. The oils were extracted from the seeds using green techniques: cold-pressing, ethanol solvent, and ultrasound-assisted ethanol solvent extraction.Different techniques compared the production yield and quality characteristics of the oil samples. On average, linoleic acid (72.00%), oleic acid (11.76%), and palmitic acid (11.50%) were the predominant fatty acids in oils. The yield (16.80%) of the ultrasound-assisted technique was observed to be more effective than the others. The lowest content of acidity and the highest content of total carotenoids were found in the cold-press oil. The color, conjugated diene-triene values were higher with cold-pressing. The total phenolic contents and the antioxidant capacities were ranked in the following order: ethanol solvent (241.1 mg kg-1 and 79.84%), ultrasound-assisted (167.0 mg kg-1 and 67.18%), and cold press (131.8 mg kg-1 and 59.04%). The total tocopherols (1801.2 mg kg-1) content was superior in the oil extracted with the ethanol solvent technique. The results were shown that the oil obtained by using the ethanol solvent extraction technique had better bioactive properties and so, antioxidant activity compared to other green extraction techniques.
Demirköprü Baraj Gölü’nde İlk Viviparus contectus (Millet, 1813) Kaydı ve Bazı Biyometrik Parametrelerinin Değerlendirilmesi
Authors: KUTLUYER Filiz , KOCABAŞ Mehmet
Published: January 2022

Manisa İli sınırları içerisinde yer alan Demirköprü Baraj Gölü’nde yaşayan Viviparus contectus (Millet, 1813) türüne ait bazı biyometrik özelliklerinin araştırılması amaçlanmıştır. Çalışma alanında toplanan, toplam 180 bireye ait genişlik (mm), yükseklik (mm), apertur yüksekliği, vücut helezon yüksekliği ve genişliği (mm), spir yüksekliği (mm) verileri dijital kumpas ile; bireylerin ağırlıkları (g) hassas terazi kullanılarak ölçülmüştür. Bireylere ait veriler sırasıyla; ortalama kabuk yüksekliği 20.23±5.16 mm, kabuk genişliği 16.11±3.33 mm, apertur yüksekliği 11.93±2.39 mm, apertur genişliği 9.71±2.11 mm, vücut helezon yüksekliği 15.71±3.87 mm, spir yüksekliği 4.49±1.73 mm ve ağırlıkları 4.50±0.93 g olarak belirlenmiştir. Temel bileşenler analizine göre, Kabuk yüksekliği (KY), Kabuk genişliği (KG), Apertur yüksekliği (AY) ve Vücut helezon yüksekliği (VHY) arasında güçlü bir ilişki olduğu belirlenmiştir. Demirköprü Baraj Gölü’nde yaşayan V. contectus türü bu çalışma ile bölgeden ilk defa rapor edilmiştir.
Evidence on the Benefits of Probiotics for Preterm Infants
Authors: AM Campos-Martinez , E Fernández-Marín , A Ruiz-López , I Cubero-Millan , M Gonzalez-Bolivar , J Uberos
Published: January 2022

This article reviews the evidence for the use of different strains of probiotics in the prevention of prevalent pathologies in premature infants. A systematic review was conducted of the use of probiotics in neonates with less than 37 weeks’ gestational age, based on a search for systematic reviews and observational and experimental studies performed during the period January 2014 to February 2021. For this purpose, the PubMed, MEDLINE and Cochrane Library databases were consulted. The aim of this article was to review the existing data on the relationship between the administration of probiotics (with different strains and doses) and the risk of necrotising enterocolitis (NEC), mortality, late sepsis and other disease parameters in premature infants. The literature search obtained 240 articles, of which we selected 16, representing a total sample of over 200,000 premature infants. Analysis of the data obtained reveals statistical evidence that the combined administration of probiotics (especially Lactobacillus and Bifidobacterium strains) reduces the incidence of grade II or higher NEC, all-cause mortality, late sepsis, length of hospital stay and time until complete enteral nutrition is achieved. However, no benefits were apparent with respect to alleviating bronchopulmonary dysplasia, retinopathy of prematurity or intraventricular haemorrhage. Further research is needed to determine the most appropriate strains, doses and treatment time for preterm infants to achieve the health benefits identified.
Nephron progenitor cells in development and disease
Authors: Dickinson Kyle , Bernard Chantal , Iglesias Diana , Goodyer Paul
Published: January 2022

The emergence of nephron progenitor cells (NPCs) in early embryonic life leads to the many rounds of nephrogenesis that result in a richly endowed kidney by the end of gestation. A delicate balance between NPC differentiation and self-renewal must be maintained to guarantee optimal nephron endowment. Genetic errors which disturb NPC cell fate can result in premature NPC depletion and renal hypoplasia/dysplasia or permit the B-catenin mutations that accompany malignant transformation into a Wilms tumor. Retention of a small population of NPCs scattered throughout the adult kidney are important for recovery from acute tubular injury later in life. In this review, we cover the role of NPCs in both mammalian kidney development and disease.
Circadian rhythms: influence on skin cancer and exposure paradigms
Authors: Smith David
Published: January 2022

Approximately 10% of genes oscillate according to a circadian clock. Even though cells are capable of independent oscillation there is a master controller in the brain, the suprachiasmatic nucleus (SCN), that provides a coordinated response throughout the body, influenced by daily and seasonal patterns of light and heat. These genes have widely varied functions but are significantly influential in DNA damage repair, the cell cycle, cellular proliferation and apoptosis, as well as metabolic function. Normal circadian rhythms are essential for the body’s natural defence against disease and cancer. Deregulation may enhance the capacity for carcinogenesis in the skin and the influence of the circadian clock helps explain two of the anomalies of melanoma exposure patterns: A higher incidence amongst indoor as opposed to outdoor workers and on intermittently as opposed chronically exposed skin.
Non-Aneurysmal Subarachnoid Hemorrhage in COVID-19: A Case Report and Review of Literature
Authors: Ray Adrija , Roy Dipayan , Ghosh Ritwik , Das Shambaditya , Benito-León Julián
Published: January 2022

Background: Hemorrhagic cerebrovascular events, either due to aneurysmal rupture or spontaneous subarachnoid hemorrhage (SAH), are not rare in COVID-19. Several mechanisms such as coagulopathy, cytokine storm, viral endotheliopathy, hypertension, and immune modulation might play a role in the pathogenesis of SAH in COVID-19. This study aimed to report the first case of spontaneous non-aneurysmal SAH associated with SARS-CoV-2 from India. We briefly discussed the possible pathogenetic mechanisms underlying this process and succinctly reviewed the relevant literature. Case report: We herein report a case of a non-comorbid young woman infected with SARS-CoV-2 presenting with thunderclap headache and eventually non-aneurysmal SAH, who recovered with conservative management. Conclusion: Headache, although a very common clinical feature of COVID-19 itself, must be investigated in detail to identify alternate causes that may be life-threatening. This case also incites further enquiry into the possible pathogenic mechanisms of neurovascular complications in COVID-19.
Symptomatic slow-acting drugs (SYSADOAs)/disease modifying anti-osteoarthrosis drugs (DMOADs) in the treatment of osteoarthrosis: what is the opinion of the different rheumatology/osteoarthritis societies in 2021?
Authors: Volpi Nicola
Published: January 2022

The various Rheumatology/Osteoarthritis Societies (the American College of Rheumatology, the Arthritis Foundation, the European League Against Rheumatism, the National Institute for Health and Care Excellence, the European society for clinical and economic aspects of osteoporosis and osteoarthritis, and the Italian consensus on appropriateness of osteoarthrosis therapies) published specific recommendations for the management of osteoarthrosis affecting hand, hip and knee. These evidence-based guidelines take into account safety and tolerability of pharmacological and non-pharmacological interventions available from the scientific literature as well as the opinions of the clinical specialists to provide complete, clear and transparent recommendations for the management of osteoarthrosis. This article provides an update of the scientific literature for selected treatments of osteoarthrosis focusing on the therapy with symptomatic slow-acting drugs (SYSADOAs) and disease modifying anti-osteoarthrosis drugs (DMOADs) (chondroitin sulfate, glucosamine, diacerein, unsaponifiable soy and avocado extracts). Moreover, the management of osteoarthrosis pain and function, avoidance of adverse events and long-term outcomes by SYSADOAs/DMOADs molecules is considered. Finally, based on the real-world data, the opinion of the various Rheumatology/Osteoarthritis Societies of all over the word is illustrated and discussed also by considering the structure, quality and properties of the SYSADOAs/DMOADs agents used in the treatment of osteoarthrosis. In particular, the results reported in numerous studies are contradictory and not always convincing about the efficacy of chondroitin sulfate and glucosamine as SYSADOAs and DMOADs. The cause of these non-homogeneous results could be due to the use in different studies of chondroitin sulfate and glucosamine preparations of varying quality. It is therefore mandatory to carry out new clinical studies using chondroitin sulfate and glucosamine of pharmaceutical grade or of the best possible quality to ascertain their usefulness as biomolecules in the treatment of osteoarthrosis.
Learning English through International Student Exchange Programs: English Education Department Students’ Voices
Authors: Suryanto Suryanto , Ayuza Betha Labova , Othman Noor Ahnis
Published: January 2022

English language learning is a process that students must go through in order to reach the optimum level of proficiency in the language. International student exchange programs are activities that might assist students in practicing and improving their English. The purposes of this study were to investigate the benefits and to identify the challenges of participating in an international student exchange program while studying English at the English Language Education Department of an Islamic Private University in Yogyakarta. The research design for this study was a qualitative descriptive one. The data for this study were gathered through interviews.  Three students from the English Language Education Department of a private Islamic university in Yogyakarta participated in this investigation. The first finding concerned the advantages of participating in an international student exchange program while studying English. It shown that participating in international student exchange programs aided students in making foreign friends, interacting with native English speakers, practicing, and improving their English abilities, and boosting their self-confidence. The second result concerned the challenges associated with participating in an international student exchange program to improve their English. It demonstrated that students who participated in an international student exchange program failed to engage with local people outside of school and experienced culture shock. All associated parties, including students, host universities, university senders, and the program's committee, should organize and execute the program's activities with care and attention, beginning with the program's planning, preparation, deployment, evaluations, and follow-up.
Sekolah Ramah HAM Sebagai Upaya Penanggulangan Tindakan Kekerasan di Kalangan Siswa
Authors: Gunawan Yordan , Hafiz Mohammad Bima Aoron
Published: January 2022

Pada dasarnya setiap orang memiliki hak asasi manusia (HAM) yang melekat sejak dilahirkan dalam kehidupannya. HAM melekat pada manusia sebagai makhluk ciptaan Tuhan. Dari itulah HAM wajib dihormati, dijunjung tinggi, dan dilindungi negara, hukum, serta pemerintah, demi kehormatan dan perlindungan harkat dan martabat manusia. Diseminasi nilai-nilai HAM di usia sekolah merupakan salah satu bentuk penanaman nilai-nilai HAM sejak dini, terutama dengan maraknya kasus kekerasan antar siswa, bullying, sampai dengan kejahatan yang mengakibatkan korban jiwa di kalangan siswa sekolah. Upaya ini dilakukan karena anak yang akan menjadi generasi penerus bangsa di masa akan datang. Program Pengabdian masyarakat berupa inisiasi Sekolah Ramah HAM adalah salah satu cara yang diharapkan mampu mengurangi dan mencegah kekerasan di kalangan siswa terus meningkat. Lokasi Pengabdian ini adalah Madrasah Muallimin dan Madrasah Muallimat yang berlokasi di Kota Yogyakarta. Program ini tidak hanya melibatkan antara peserta didik dengan guru tapi juga seluruh warga sekolah dan masyarakat sekitar sekolah serta orang tua murid. Setelah terbentuknya Sekolah ramah HAM ini diharapkan siswa dapat memahami serta menjunjung tinggi HAM itu sendiri, serta berkurangnya tindak kekerasan, terutama bullying di kalangan siswa di Kota Yogyakarta.
PEMANFAATAN TEKNOLOGI ANDROID UNTUK DETEKSI DINI PENYAKIT JANTUNG DAN KARDIOVASKULAR
Authors: Fitrianingsih Fitrianingsih , Elisma Elisma , K Fatnur Sani , Utami Diah Tri , Prajuwita Mia
Published: January 2022

Tingginya angka prevalensi penyakit jantung dan kardiovaskular sangat erat kaitannya dengan penyebab kematian tertinggi di Indonesia. Hal ini bisa dicegah dengan deteksi dini penyakit jantung dan kardiovaskular sehingga bisa menghindari faktor resiko penyebab terjadinya penyakit tersebut. Salah satu upaya dan langkah praktis di era globalisasi saat ini adalah pemanfaatan teknologi android berbasis kesehatan untuk deteksi dan monitoring gejala klinis dari penyakit jantung dan kardiovaskular. Target utama pengabdian ini adalah civitas akademika di FST Unja. Diketahui potensi penggunaan smartphone di kalangan civitas akademika sangat tinggi tetapi untuk penggunannya dalam kesehatan masih banyak yang belum mengetahui dan belum optimal. PPM ini bertujuan untuk meningkatkan pengetahuan dan pemahaman mengenai pentingnya deteksi dini penyakit jantung dan kardiovaskular serta pemanfaatan teknologi android dalam optimalisasi kualitas kesehatan civitas akademika FST Unja. Metode yang dilakukan dalam program PPM ini yaitu dengan metode observasi, pendataan dan pelaksanaan melalui kegiatan penyuluhan disertai demo penggunaan aplikasi kesehatan pada smartphone dan evaluasi. Hasil dari kegiatan PPM ini adalah meningkatnya pengetahuan dari civitas akademika sebesar 80% serta mampu mengoperasionalkan penggunaan aplikasi kesehatan berbasis Android pada smartphone untuk mengetahui gejala klinis dari penyakit jantung dan kardiovaskular. Kegiatan ini berkontribusi merealisasikan dan menyosialisasikan program pemerintah “Heart-Healthy Environment” atau “Lingkungan Sehat bagi Jantung”.
New paradigm shift in the times of pandemic: Effects and influence of covid-19 on prosthodontic practice
Authors: Pathania Neha , Kanwar Rohi , Thakur Anuja , Nagpal Archana , Behl Jyoti
Published: January 2022

The coronavirus disease 2019 (COVID-19) pandemic has put the world in a panic situation. It has been evident that the geriatric population is more susceptible to get this infection, mainly due to advanced age and comorbidities and thus reduced immunity. In this ongoing crisis, individuals could-not visit a dental clinic, hence unattended dental needs and emergencies. The prosthodontic management in geriatric patients is essential for their well-being, as the partial or complete edentulism are very prevalent among them. However, a prosthodontist remains at high risk for exposure to the novel coronavirus through the aerosol-generation, possibly through the contaminated surfaces and the indirect contact with dental laboratories and the technicians through the impressions, dental stone casts, and the prosthetic appliances. It demands the implementation of the preventive measures, including performing emergency treatments only, rescheduling patients with suspected COVID, disinfecting surfaces and prosthodontic materials with biocidal substances, and using protective equipment such as the N95 masks, gowns, and face-shields.
Gamut of tooth coloured opportunities to reinstate the paediatric smile: A review
Authors: Ahuja Vipin , Arunima
Published: January 2022

Early Childhood Caries has been acknowledged as a root of severe decay in children at a global level. Most frequently we see involvement of upper incisors followed by the molars. This disturbs the phonetics and most importantly the aesthetics of the child. Over the years, there have been plenteous studies concerning the restoration of primary teeth. As the technology advanced, the level of parental satisfaction with the conventional stainless-steel crowns lowered, this made the Paediatric dentists to search for an aesthetic restoration for the decayed primary tooth. Treatment of decayed anterior teeth can be done by a variety of techniques which includes Strip crowns, Polycarbonate crowns, Cheng crowns, acrylic crowns, Zirconia crowns and the most recent is Figaro crowns. The advent of such advanced techniques and materials helps in creating beautiful restorations which help children to improve their self-image as the child aesthetics is the guide to the adult aesthetics. This article gives an overview of few of the aesthetic options for rehabilitation of ECC cases.
Comparing color stability of 3 different resin composites after immersion in staining media: An in vitro study
Authors: Vyas Aarshati , Shah Shilpa , Patel Nishtha , Shah Setu P , Chaudhary Harshvardhan , Jani Karna
Published: January 2022

The aim of this study was to evaluate colour stability of three different composite resins.

Thirty disc-shaped specimens of three different light‑cured resin composites Filtek 3M ESPE, Beautifill Injectable (Shofu) and Beautifill 2 (Shofu) were prepared. For evaluation of colour stability, samples were evaluated for baseline color value using a spectrophotometer. Later, color measurements were taken after 1 week immersion in Green Tea by spectrophotometer and color change values were calculated. Statistical analyses were executed by one-way ANOVA and Scheffe’s post hoc procedure.

All materials showed significant color change after 1 week (P < 0.05) of immersion in Green Tea, with the lowest color alteration observed at the 1st day and the highest observed after the 7th day. Among the materials tested, the lowest color alteration was detected in Beautifil 2 and the highest color alteration was detected in Filtek Z250XT.

All the materials tested for evaluating colour stability showed apparent colour changes after 1 week.
El concepto de trabajo: perspectiva histórica
Authors: Cristancho Giraldo Laura Andrea
Published: January 2022

A partir de un reconocimiento del significado de trabajo en la historia del hombre, el presente artículo expone las diferentes maneras como se ha concebido el trabajo desde la profunda transformación de las sociedades campesinas a las ciudades levemente industrializadas con las que culminó la Edad Media, dando así inicio a la denominada Modernidad; el hito histórico del descubrimiento de América con los grandes contrastes de una sociedad avanzada y unos grupos indígenas con sus saberes ancestrales propios de sus culturas nativas, que lentamente se vieron obligados a adaptar sus saberes a los de sus colonizadores y en algunos casos conquistadores, hasta el pensamiento contemporáneo en donde el trabajo intelectual cobra especial fuerza y valor social y, finalmente, es expuesto el concepto de trabajo en Latinoamérica hasta finales del siglo XX.
Signals of electromagnetic tool with toroidal coils in deviated wells (following numerical simulation results)
Authors: Mikhaylov I. V. , Surodina I. V. , Temirbulatov O. P.
Published: January 2022

The study is aimed at analyzing the applicability of the logging tool with toroidal coils in the sections of deviated oil-and-gas wells. We carried out a three-dimensional finite-difference simulation of the electromagnetic signals in geoelectric models of oil-, gas-, oil-water- and water-saturated reservoirs for the entire set of operating modes, frequencies and positions of the receiver toroidal coils. Characteristic features of the signals were revealed depending on the resistivity contrast and reservoir thickness at various well deviation angles.
Electrical anisotropy of terrigenous deposits: a brief overview of approaches to its determination from electrical logging data in vertical wells
Authors: Suhorukova K. V. , Petrov A. M.
Published: January 2022

The article briefly reviews a number of publications on the problem of determining rocks electrical resistivity anisotropy (primarily of sedimentary genesis) using downhole resistivity logs. We provide the information on the main causes of sandy-clay sediments micro- and macroanisotropy according to Russian papers and the history of the model-based approaches to the resistivity anisotropy description according to Russian and foreign articles. We analyze the main approaches to the vertical resistivity estimation. Both new hardware solutions aimed at direct measurement of electromagnetic field components sensitive to anisotropy and methodological techniques for extracting this information from the signals of "conventional" resistivity logging tools are considered according to published studies. The hardware solutions are multicomponent measurements with inclined and perpendicular (to the tool axis) coils, as well as with coaxial toroidal coils. Methodological techniques include combining data measured by tools with different types of medium excitation, for example, induction and galvanic. A number of papers suggest a two-step scheme: the first step is to determine the horizontal resistivity using induction arrays data, and the second step is to determine the vertical resistivity using focused lateral logs. Such schemes are implemented using numerical inversion algorithms and in some cases by inventing transformations of measured signals. Adding anisotropy to the interpretational model is based on a priori data (core studies, microresistivity logs). In the absence of a priori data, anisotropy is added when it is impossible to reconcile the parameters of isotropic models built independently based on logs with different type of excitation. A special focus of the review is on the development of the theory of unfocused lateral logging (BKZ) method by Soviet and Russian scientists and on the history of research on the electrical anisotropy influence on the signals of gradient probes. Due to the widespread use of the method in the USSR, this topic is presented in a number of papers revealing the results of anisotropic geoelectric models theoretical studies, numerical and physical modeling of BKZ logs and methodological developments for their interpretation.
Entrevista a Gonzalo Aguilar
Authors: Lázaro Igoa Rosario
Published: January 2022

Gonzalo Aguilar (1964) es un crítico argentino que se ha ocupado de la poesía concreta brasileña y de Augusto de Campos por diferentes vías. Publicó La poesía concreta: las vanguardias en la encrucijada modernista (2003, traducido al portugués en 2005), un abordaje pionero fruto de su tesis doctoral. De Augusto de Campos, seleccionó y prologó la antología Lenguaviaje, que cuenta con varias ediciones. Asimismo, ya había publicado las antologías Poemas (1994) y Poetamenos (2014), en colaboración con Gerardo Jorge. En cuanto a antologías de varios autores, publicó Galaxia concreta (1999), de Augusto de Campos, Haroldo de Campos y Décio Pignatari. En 2014, curó la muestra de Augusto de Campos Despoemas en Argentina (2014). Aguilar tiene un doctorado por la Universidad de Buenos Aires. Es profesor a cargo de la cátedra de Literatura Brasileña y Portuguesa, en la Facultad de Filosofía y Letras de la misma universidad, y Director de la Maestría de Literaturas de América Latina de la Universidad Nacional de San Martín. Es asimismo autor de libros sobre cine como Otros mundos (Un ensayo sobre el nuevo cine argentino) (2006) que fue traducido al inglés. Dirige, junto con Florencia Garramuño, la Colección Vereda Brasil de la editorial Corregidor. Ha traducido numerosos autores brasileños al castellano.
A interação entre Josef Albers e Augusto de Campos
Authors: Waltrick do Amarante Dirce , Medeiros Sérgio
Published: January 2022

Um breve poema visual de Augusto de Campos que é uma tradução de Maiakóvski dialoga com a monumental série Homenagem ao quadrado, do artista plástico Josef Albers, inspirada, em parte, nas pirâmides e na paisagem mexicanas.
Passeio pelas lembranças com Augusto de Campos
Authors: Bernardini Aurora
Published: January 2022

O texto trata de relembrar alguns dos momentos mais marcantes das traduções poéticas de Augusto de Campos, a começar pelas francesas de Mallarmé e Válery, onde é dada ênfase particular ao uso que ele faz do ritmo que acompanha o sentido. Passa-se, depois, às traduções russas que focalizam a poesia de Marina Tsvetáieva onde, ao lado da fidelidade tradutória, começa-se a notar a utilização de um léxico interpretativo com certa distância do original. Nas traduções dos poetas ingleses e americanos, foi focalizado um fragmento de Gertrude Stein e a estratégia de “ler com os ouvidos” de Augusto de Campos, e na tradução do soneto “O dia do juízo” do italiano Agostino Belli, comparada com a tradução do mesmo soneto por Anthony Burgess, foram focalizadas as soluções dadas ao grotesco em termos de criações de “malapropismos” da linguagem popular. Finalmente, num poema de Emily Dickinson, surgiu uma nova estratégia: ao lado da tradução paralela do léxico do poema, o acréscimo de um novo termo (conceito) que não existe literalmente no original, criado para evocar uma certa ambiência, em termos da A-tradução proposta por Derrida.
Levels of incompetence. On the place of rationality in an irrational world
Authors: Kobylarek Aleksander , Alam Sohaib , Gaziova Maria , Madej Martyna
Published: January 2022

The phenomenon of incompetence as an interdisciplinary subject requires multiple analyses embracing various spheres of life, and scientists whose knowledge is limited to only one discipline may face difficulties in capturing the core of the issue. This article is based on a meta-reflection inspired by the discourse revealed in post-humanist and post-pandemic reality. Its aim is to define sources of irrationality, areas of ignorance and, above all, levels of incompetence to reveal the primary categories. One of the problems standing in the way of development is a lack of interest, which leads to ignorance. A limited number of experiences and stimuli different from those in our everyday lives can lead us to a perception of the world solely from our own perspective. In the political sphere, cooperation between the authorities and specialists for the good of the community is crucial. The greed for power and money is fatal, causing numerous abuses, scientific knowledge becomes “inconvenient”, so it is easier to ignore it. A lack of unanimity among researchers and a divergence of views, cause the people who are not fully aware of how science works to begin to doubt it, which increases the obstinacy of their own views. It is impossible not to question and to systematize knowledge completely; the problem arises at the level of the dissemination of knowledge. Moreover, emotions and the phenomenon of resentment play one of the key roles in rationality, and controlling them and continuing education can reduce the phenomenon of incompetence.
Influence of «sensory prehistory» on the ambiguous stimuli processing in the human brain
Authors:   Immanuel Kant Baltic Federal University, Kuc Alexander , Maksimenko Vladimir ,   Immanuel Kant Baltic Federal University, Hramov Aleksandr ,   Immanuel Kant Baltic Federal University
Published: January 2022

Purpose of this work is to study the effect of previous sensory information on the brain’s processing of current visual stimuli. Bistable images (Necker cubes) with a high degree of ambiguity (HA) and a low degree of ambiguity (LA) were used as visual stimuli. Methods. In this paper, we used wavelets to identify features of the brain activity signals. A multivariate analysis of variance was used to compare behavioral characteristics. Spectral power and event-related spectral perturbations were compared via a cluster-based permutation test using the FieldTrip package for Matlab. Results. We found that when the HA stimuli followed the LA stimuli, the activity of neurons in the sensory areas decreased in the early processing stage but increased in the later stages. This result confirmed the hierarchical organization of processing, where the low levels processed the details of the stimulus, and the high levels represented its interpretation. We supposed that processing of HA and LA stimuli was similar at low levels due to their similar morphology. Therefore, the brain might use the LA stimulus template at low levels to reduce the demands when processing the details of the HA stimulus. When the LA stimulus followed the HA stimulus, a weakened response in the sensory regions accompanied a high response in the frontal cortex. It reflected activation of the top-down cognitive functions, detecting a mismatch between the LA stimulus and the HA stimulus template. Conclusion. These results expanded the existing knowledge about the sensory processing mechanisms.
Hemodynamic response in the motor cortex to execution of different types of movements
Authors:   Innopolis University, Badarin Artem , Grubov Vadim ,   Innopolis University, Andreev Andrey ,   Innopolis University, Antipov Vladimir ,   Innopolis University, Kurkin Semen ,   Innopolis University
Published: January 2022

Purpose of this work is the analysis of the hemodynamic response to the execution of various types of movements (single movement, series of movements, “tapping”) by the right hand. Methods. In this paper, the hemodynamic response was recorded using functional near infrared spectroscopy (NIRScout instrument from NIRx, Germany). The NIRScout system uses 16 optodes (8 sources and 8 detectors) to record the hemodynamic response in the cerebral cortex with a sampling rate of 7.8125 Hz. Optodes are non-invasively placed on the patient’s scalp by inserting into the sockets of a special cap “EASYCAP”. Results. We show that the total hemodynamic response in the motor cortex of the left hemisphere slightly differs between all the considered types of movement, while the severity of contralaterality demonstrates significant differences between the types of movements. Contralaterality is most pronounced when performing a series of movements, while a single squeeze of the hand causes the least contralaterality. Conclusion. The results obtained in this paper demonstrate the high sensitivity of functional near-infrared spectroscopy technology to the performance of various types of movements. It should be especially noted here short single hand squeezes, which are clearly visible on the characteristics of HbO and HbR, which can be used in the development and design of various brain – computer interfaces, including multimodal ones.
Level of Education and Perceptions of the Quality of Services to Prevent Radicalism: A Study in Poso District, Indonesia
Authors: Karsono Bambang
Published: January 2022

This study analyzes the differences in public perceptions of the quality of radicalism prevention services from the point of view of the level of education. Education has been used to radicalize and deradicalize youth. Governments in conflict-affected countries have an interest in funding measures against violent extremism as part of education programs. After the social conflict in the Poso district, the local government implemented some policies aimed at preventing the emergence of radicalism. The results of the study of 456 respondents from four elements of the population, namely the army, police, government employees, and the general public, showed that the level of education was the difference between people’s perceptions of the quality of radicalism prevention services. Respondents with high school education were able to have a higher average response than those with a college education.
La comunicación de políticas educativas de la Dirección General de Cultura y Educación (DGCyE), provincia de Buenos Aires, Argentina. Significaciones, desplazamientos y articulaciones hegemónicas (2018-2019)
Authors: Martínez Darío G. , Morabes Paula
Published: January 2022

En este artículo se analiza la comunicación de las políticas públicas educativas de la Dirección General de Cultura y Educación (DGCyE) de la provincia de Buenos Aires, Argentina. El periodo considerado se encuentra entre el 2 de agosto de 2018 y el 16 de abril de 2019. Los materiales relevados son las diferentes publicaciones que la DGCyE realizó en su cuenta oficial de la red social Twitter (@BAeducacion), enmarcado todo metodológicamente dentro de la teoría fundada. Un propósito del trabajo es describir, en clave comunicacional, las políticas públicas de este organismo para problematizarlas como un territorio de disputa por la significación. Asimismo, se busca indagar las articulaciones hegemónicas que este instala. Por otro lado, se investiga cuál es la política de significación de la DGCyE y los desplazamientos que se observan en el campo de la comunicación/educación. Se concluyó que existió un desplazamiento de las políticas públicas universalistas hacia otras focalizadas y una retracción de los discursos relacionados con la inclusión y los derechos humanos.