bluuebunny/crossref_metadata_2025 huggingface dataset:
Cumhuriyet Dönemi Eğitim Politikaları Kapsamında Vatandaşlık Eğitiminin İncelenmesi
Authors: Batu Hüseyin Avni
Published: November 2024

The individuals who are the source of a country's existence are the most basic values of that country. It is the most important duty of every state with this value to cultivate and preserve its own self-values in the most beautiful way and to prepare for the future. The desire to raise up citizens who live in their own country and are connected to their own country and nation is one of the foremost goals of every state. Citizens ensure and build the future of a country.Jul. Every state with this consciousness will want to educate and guide its citizens, who have their own values, in the best way and educate them in accordance with their own state goals. There is always a need for individuals who serve the country of which they are citizens, produce, develop themselves, and work for the benefit of the country and the nation as a country and a nation. The greatest goal of the state is to educate its citizens, especially children and young people, who are the guarantee of the future, on the axis of this goal. The individual, who is a social being, is always learning and improving himself in society. With the influence of the social environment, education does not only stay in schools, it continues in all areas of life. In this context, the target of the country's citizens to be educated is not only the school youth, but a comprehensive education is aimed at every member of the country to gain awareness for the benefit of the country. There is a total educational goal in our country both with the educational system, with its social and cultural opportunities and with the means of broadcasting. An individual who has national and spiritual values, serves for his country, develops himself, is successful in social and professional life is the citizen profile that our country targets. Through a comprehensive education, both children and young people and adults want to be raised in accordance with the purpose of a good citizen aimed at by the state. This citizen profile has become the priority target of the newly established state with the Republic.
KeyWords: Republican Period, Education Policies, Citizenship Education
Gizli Soruşturmacının Konuta Girme Yetkisi ve Bu Yetkinin Kapsamı Üzerine Bir İnceleme
Authors: Boyracı Ali
Published: November 2024

Türk hukukunda gizli soruşturmacının konuta girme yetkisinin bulunup bulunmadığı oldukça tartışmalı bir konudur. Bu durumun temel sebebi ise kanunda konuya ilişkin açık bir düzenlemeye yer verilmemiş olmasıdır. Oysa Türk hukukundan farklı olarak, Alman hukukunda gizli soruşturmacının konuta girme yetkisi ile ilgili özel bir hüküm sevk edilmiştir. Buna göre, gizli soruşturmacı, mahkeme tarafından onay verilmesi (Alman CMK §110b paragraf 2 bent 2) ve değiştirilmiş kimliğini kullanarak ilgilinin rızasını elde etmesi (Alman CMK § 110c) şartıyla, herkesin girmesine açık olmayan (açık bir rıza bulunmaksızın girilmesi mutat olmayan) bir konuta girebilecektir. Bununla birlikte, Alman CMK § 110c hükmünün anayasaya uygun olup olmadığı Alman hukukunda tartışmalıdır. Bu çalışmada gizli soruşturmacının konuta girme yetkisi ve bu yetkinin kapsamına ilişkin Alman hukukundaki kanuni düzenleme, öğretideki görüşler ve yargı kararları ile Türk hukukundaki öğreti görüşleri incelenerek, konuya ilişkin değerlendirmelerimize ve önerilerimize yer verilmiştir.
Tasa de egreso hospitalario por amputación traumática del pie y/o tobillo entre los años 2018 y 2022 en Chile: un análisis descriptivo epidemiológico
Authors: Villalobos Arzic Matías , Abarca Cubillos Joaquín , Sotomayor Arribas Juan , Díaz Araya Siam , Oyarzún Martínez Daniel , Jorquera Carrasco Bárbara
Published: November 2024

Introducción: La amputación traumática pie-tobillo es una emergencia médica de alta morbimortalidad que compromete estructuras distales a la articulación tibioastragalina, requiere atención hospitalaria inmediata con implicancias significativas. La escasez de datos epidemiológicos chilenos justifica la necesidad de investigación local. Objetivo: Describir la tasa de egresos hospitalarios por amputación traumática del pie y/o tobillo en Chile entre 2018 a 2022, por sexo y grupo etario, además del promedio de estadía hospitalaria. Metodología: Cuantitativa, observacional, descriptiva y transversal, a través de análisis secundario de datos sobre egresos hospitalarios por amputación traumática de pie-tobillo en Chile 2018-2022 (N= 543). Se calculó tasa egresos hospitalarios y promedio de estadía. Resultado: La tasa de egresos hospitalarios fue 0,62 por cada 100.000 habitantes. El sexo masculino presentó mayor tasa (1,03) que el femenino (0,22). El grupo 65-79 años mostró la mayor tasa de egresos hospitalarios (2,01), promedio de estadía hospitalaria general 11,06 días, mayor en sexo masculino (11,61) versus femenino (8,62). Discusión: La tasa de egresos hospitalarios es inferior a países desarrollados, posiblemente por diferencias en sistemas de registro o exposición a factores de riesgo. La disparidad entre sexos sugiere mayor exposición masculina a actividades de riesgo. La elevada tasa en el grupo de 65-79 años contrasta con la literatura, posiblemente por vulnerabilidad asociada al envejecimiento. Conclusión: Este estudio proporciona una caracterización epidemiológica, subrayando la necesidad de estrategias preventivas en grupos de alto riesgo y la importancia de medidas de seguridad laboral vigentes. Se requieren investigaciones futuras sobre etiologías específicas y resultados funcionales a largo plazo.
Production of Alkaline Serine Protease from Bacillus subtilis MTCC 8601
Authors: Kumar Sura Narendra , S. Lal Vignesh , Rajeev Ahalya
Published: November 2024

Alkaline serine protease is a proteolytic enzyme having a wide array of industrial applications. These proteases have a high enzymatic activity at a high pH ranging between 8-12 and temperature 38℃, hence finding its importance in industries such as detergent industries where pHs reach as high as 10.7 due to the presence of caustic soda and other alkaline materials. Production of alkaline serine protease from Bacillus subtilis MTCC 8601 on establishment of a shake flask fermentation protocol has been carried out in this study. Qualitative analysis using the Biuret test has been conducted, quantification of protease in the crude enzymatic extract was carried out using Lowry’s method of quantitative analysis which was found to be 0.847 mg/ml. Further, the enzymatic activity of the protease has been determined using the high sensitivity Ninhydrin method of amino acid detection for which the results were 3.51 mg/ml when Bovine serum albumin was used as a substrate and 1.419 mg/ml when Gelatin was used as a substrate, the unit of enzyme is found to be 0.445 μg/ mol min and 0.180 μg/ mol min for each substrate respectively.
Langvarig utmattelse ved sykdom: forekomst, årsaker, konsekvenser for arbeidsfunksjon og klinisk helsepsykologiske tiltak
Authors: Berge Torkil , Fjerstad Elin
Published: November 2024

Objectives: Physical and mental fatigue is part of the symptom pattern for several diseases that causes adverse impacts on the patient’s daily functioning and quality of life and imposes significant social costs. The objective was first to present an overview of the incidence of and the complex causal mechanisms contributing to prolonged fatigue caused by illness, and then to present documentation of cognitive behavioural therapeutic approaches.

Methods: We searched the databases Medline, PsycInfo, Cochrane Library, Embase and Academic Search Elite using terms such as “fatigue”, “cognitive behavioural therapy”, “chronic disease”, “cancer”, other diagnosis-specific terms, and “systematic reviews” as far as May 2024. It was a non-systematic, narrative literature review, with an emphasis on representative meta-analyses that could provide a picture of the state of knowledge.

Results: Cognitive behavioural therapeutic approaches are proven to have a beneficial effect on fatigue associated with a wide range of diseases.

Conclusions: Fatigue is a transdiagnostic symptom across a range of diseases, which offers an opportunity for generic psychological treatment approaches that can be individually tailored. Patients should be assessed for fatigue and, when necessary, be offered specific knowledge and proven strategies for managing fatigue and improving daily functioning.

Keywords: fatigue, chronic disease, cancer, cognitive behavioural therapy, clinical health psychology, review
Hjerteinfarkt og posttraumatisk stressreaksjon: en kvalitativ studie
Authors: Næss Eva Therese , Lund June Straumsnes , Jakobsen Judith Margrethe , Smines Aina Iren Gulliksen , Lorem Geir
Published: November 2024

An increasing number of people survive myocardial infarction, and research suggests that psychological difficulties are prevalent among heart patients. The aim of the study was to examine the participants’ psychological reactions to myocardial infarction. The study was based on 27 semi-structured interviews. Three central themes emerged: 1) experiences of myocardial infarction and subsequent psychological reactions, 2) experiences of health services, particularly rehabilitation and 3) the significance of health information. The results indicate widespread psychological difficulties among the participants. Several describe the infarction as a traumatic event with stress-related symptoms. The participants’ experiences of their encounters with the health services varied, and they described various factors associated with hospitalisation and rehabilitation as protective or stressful. Lack of health information was found to be stressful, and created uncertainty and unpredictability for the participants. The findings suggest that the participants have psychological reactions following a myocardial infarction. These difficulties impose limitations on daily life activities, and many require more psychological support and better tailored health information than what is currently provided .

Keywords: Myocardial infarction, PTSD, anxiety, depression, qualitative study, rehabilitation
Characterization of PVA Dispersed Cholesteric Liquid Crystal; Investigation of Optical and Dielectric Properties
Authors: Santosh Mani
Published: November 2024

Composite materials by dispersing polymer into cholesteric liquid crystals (CLC) are very useful to minimise many drawbacks of pure liquid crystals like threshold voltage, contrast ratio, stability etc. These materials are used for many applications like light shutters, smart windows in addition to display. The present paper is an attempt to study and compare optical and electrical properties of pure and composite CLC. The polyvinyl alcohol of different concentrations was dispersed to cholesteryl palmitate by chemical method. The study of optical properties was performed by polarizing optical microscopy (POM) and fabry perot scattering studies (FPSS) whereas the dielectric properties were studied by impedance analyser. It was found that the CLC shows more stability and improved performance after dispersing polyvinyl alcohol which may provide new opportunity for potential application of these materials.
Students as developers of educational tools - What educational challenges do they address and which learning approaches do they implement?
Authors: Kolås Line , Isfold Munkvold Robin , Palmquist Adam
Published: November 2024

Although game development students typically lack a formal pedagogical education, they have clear opinions and concrete ideas on improving higher education learning practice. In Excited, the Centre for Excellent IT Education, game development students were invited to pitch ideas of educational tools to improve higher education. Then, some of the student teams were offered summer jobs to implement the ideas. The study has investigated their products, and through an explorative qualitative artifact analysis, a sample of 6 student-created educational tools have been analyzed. The thematic analysis answered the following research questions; 1) What educational challenges do the students address when creating tools to improve higher education? 2) What learning approaches do students implement when they develop educational tools? The findings show that the student-created educational tools address both soft and hard skills, and exemplifies a complex learning reality for students with a necessity of learning both industry-relevant technologies, and also addressing the necessity of learning soft skills like team management. The findings also reveal a wide variation in the complexity of the educational challenges students address, evident in the scope and depth of the learning objectives embedded within the tools, including vocabulary acquisition and understanding simple commands as well as simulating intricate processes navigating a multifaceted environment. Concerning learning approaches, the analysis shows that the students have implemented tools focusing on content creation, process management, exploration, competition, collaboration, articulation and communication. The study shows how student involvement can be implemented through a role as developers of learning tools, not only as information providers, actors, experts, and partners.
Resolución bancaria y derecho concursal: interacción y fricciones
Authors: Pulgar Juana
Published: November 2024

El objeto de este trabajo es destacar y resumir, en una primera aproximación, las principales
interacciones existentes entre la resolución bancaria y el derecho concursal, las cuales en
ocasiones dan lugar a fricciones. Las raíces de estas fricciones se encuentran en los
diferentes objetivos perseguidos por cada uno de estos marcos jurídicos y en los diferentes
intereses que pretenden proteger. Paradójicamente, a pesar de estas fricciones, las
autoridades de resolución de la Unión Europea (UE) deben aplicar la legislación nacional
sobre insolvencia, que aún no está armonizada a escala europea. Y deben hacerlo no solo
en el marco de la resolución propiamente dicha, sino también de un modo contrafactual, en
situaciones ex post y ex ante, con respecto a cuestiones clave (presupuestos de resolución,
salvaguardas y jerarquía de los acreedores) que están reguladas de forma incompleta o
demasiado amplia en la directiva comunitaria que establece un marco para la reestructuración
y la resolución de entidades de crédito y empresas de servicios de inversión. Así pues, a falta
de normas específicas, este trabajo pretende arrojar luz sobre las principales tensiones
interpretativas entre las normas aplicables en materia de resolución y su contraparte
concursal.
Pengaruh Overconfidence, Toleransi Risiko, dan Perilaku Keuangan Terhadap Keputusan Berinvestasi di Bursa Efek Indonesia
Authors: Syahfitri Diah Intan , Tryana Ayu Levia
Published: November 2024

This study aims to analyze the effect of overconfidence, risk tolerance, and financial behavior on investment decisions on the Indonesia Stock Exchange. Using the Structural Equation Modeling (SEM) approach with Partial Least Squares (PLS), this study involved respondents who are millennials and active investors in the Indonesian capital market and live in Sumbawa Regency with a total of 100 respondents. Data was collected through a questionnaire designed to measure the level of overconfidence, risk tolerance, and financial behavior, as well as investment decisions made by respondents. The results of the analysis show that overconfidence has a positive and significant influence on investment decisions, where more confident investors tend to make more aggressive investment decisions. In addition, risk tolerance is also shown to contribute positively in influencing investment decisions, with investors who have high risk tolerance being more willing to invest in riskier instruments. Financial behavior, as a factor that influences the decision-making process, shows a significant relationship to investment decisions. These findings provide insights for investors and financial practitioners in understanding the psychological factors that influence investment decisions in the capital market, as well as the importance of behavior management in improving investment returns.
Algal Biyoaktif Bileşenler
Authors: Karakurluk Merve , Demiriz Yücer Tuğba
Published: November 2024

Algler ökaryötik canlılardır, Ekosistemin devamlılığı ve düzenini sağlayan algler bölünerek çoğaldığından dolayı deniz canlıları arasında geniş bir alana sahiptir. Genellikle tatlı su gölleri, çaylar, dereler, su birikintileri, nehirleri okyanuslar gibi sucul ortamlarda yaşayabilen algler, fotosentetik canlılardır. Algler yapılarında karbonhidrat, protein, lipid, vitamin, mineral, pigment, sterol gibi biyoaktif bileşiklere sahiptir. Biyoaktif bileşenler sayesinde antihipertansif, antitümör, antidiyabet, antioksidan, antiinflamatuar etkiler göstermektedir. Yüksek besin içeriği ve sağlığı geliştirici etkileri sayesinde fonksiyonel gıda niteliği taşımaktadır. Bu nedenle tıp, ilaç ve besin takviyesi, gıda, endüstri, tarım, atıkların arıtılması, hayvan yemi, gübre, biyodizel üretimi, kozmetik gibi pek çok alanda alglerden yararlanılmaktadır. Özellikle gıda sektöründe gıda katkı maddesi ve besin takviyesi olarak kullanımı yaygınlaşmıştır. Ayrıca artan nüfus ile birlikte ortaya çıkabilecek gıda kıtlığı ve besin yetersizliği problemlerine yönelik alternatif besin kaynakları arasında yer alabileceği düşünülmektedir. Zamanla kullanım alanları artış göstermekte ve doğal bir alternatif besin olarak ele alınmaktadır. Bu nedenle bu çalışmada alglerin özellikleri, yapısındaki biyoaktif bileşenler ve etkileri hakkında bilgiler verilmiştir.
Peran Media Sosial Dalam Manajemen Krisis: Insiden Kekerasan Pada Hewan Di Plaza Indonesia
Authors: Afika Nur  , Muh Akbar  , Darwis
Published: November 2024

Penelitian ini bertujuan untuk menganalisis peran media sosial dalam manajemen krisis yang muncul akibat insiden kekerasan terhadap hewan di Plaza Indonesia pada tahun 2024. Insiden tersebut menjadi viral setelah rekaman video pemukulan anjing oleh seorang petugas keamanan tersebar luas di berbagai platform media sosial, memicu kemarahan publik dan seruan boikot terhadap Plaza Indonesia. Metode yang digunakan dalam penelitian ini, menggunakan pendekatan kualitatif dengan studi literatur. Hasil penelitian menunjukkan bahwa media sosial memainkan peran penting dalam eskalasi dan penanganan krisis. Plaza Indonesia merespons dengan cepat melalui pernyataan publik, pemecatan petugas yang terlibat, yang semuanya disebarkan melalui media sosial untuk mengendalikan kerusakan reputasi. Studi ini juga mengungkapkan bahwa respons cepat dan transparan melalui media sosial mampu meredakan kemarahan publik dan membantu dalam pemulihan citra perusahaan.
Rancangan Pembuatan Puzzle 2D "Perfect Match" untuk Perangkat Android
Authors: Dhananjaya Asoka , Pragantha Jeanny , Haris Darius
Published: November 2024

“Perfect Match” adalah game puzzle match-3 dengan tampilan 2D yang dirancang untuk perangkat Android. Unity serta C# sebagai bahasa pemrograman digunakan dalam pengembangan game ini. Game ini dirancang dengan tujuan sebagai sarana hiburan dengan mengajak pemain untuk mencocokkan objek serta menggunakan strategi untuk menyelesaikan level. Uji yang dilakukan oleh dosen pembimbing menggunakan metode blackbox testing dan alpha testing, pengujian yang dilakukan terhadap responden yang berjumlah 30 dilakukan menggunakan beta testing yang melalui survei. Pengujian yang dilakukan menunjukkan hasil yakni mayoritas responden merasa tampilan dan gameplay menarik, meskipun terdapat kekurangan dalam variasi power-ups pada level lanjut.
Rol de la mediación pedagógica en el proceso de aprendizaje del español como lengua extranjera
Authors: Murillo Reyes Henry Alexander , González Solís Jader Wilder , Morales Soza Madia Gisselle , Miranda Téllez Marta Elizabeth
Published: November 2024

La mediación pedagógica como estrategia para el aprendizaje de enseñanza del Español como Lengua Extranjera ELE es una opción que favorece tanto al aprendiente como al profesor para que se lleve a cabo la efectiva adquisición. De ahí que en este artículo se presenta un breve análisis alrededor de la mediación pedagógica partiendo de elementos teórico-prácticos relacionados con el proceso de enseñanza-aprendizaje. El objetivo consistió en analizar la percepción de los actores principales del acto de enseñanza-aprendizaje sobre la importancia de la mediación pedagógica para lograr el alcance de las competencias y cumplir con los intereses de los aprendientes. La investigación se realizó mediante un enfoque cualitativo y se identificó una unidad de análisis mayor: mediación pedagógica como estrategia de enseñanza-aprendizaje. Del mismo modo unidades menores: la mediación pedagógica desde una visión centrada en el saber hacer y, la mediación pedagógica centrada en la actuación escolar y las vivencias pedagógicas en el seno de una educación centrada en el ser. Para el análisis de los datos se elaboró matriz de doble entrada. También, se aplicó triangulación de la información, considerando los objetivos, preguntas de investigación y unidades de análisis. En este artículo se presenta una descripción de elementos de algunas posturas de nivel conceptual que tienen los profesores y directores sobre el concepto de mediación pedagógica y su implicancia en el proceso de aprendizaje. Asimismo, se explica cómo los actores encargados de llevar el cabo la enseñanza, consideran en qué acciones escolares y vivencias se puede llevar a cabo el aprendizaje y su relación con los intereses de los aprendientes.
Similitud de carreras en la UNAN-Managua en el área del conocimiento salud: caso de enfermerías
Authors: Murillo Reyes Henry Alexander , Escobar Soriano Álvaro Antonio , Paiz Salgado Mariela del Socorro
Published: November 2024

La armonización curricular de carreras pertenecientes a una misma área de conocimiento es un proceso en el cual se toman en consideración aspectos que las hacen ser similares, en este caso concreto, campos de acción; plan de estudio, perfil profesional y objetivos/competencias. Es decir, para armonizar currículos de carreras dentro de una institución de estudios superior, las autoridades deben asumir de manera decisiva el fin de tener carreras que den respuestas a las demandas de país y que el plan de la carrera resultante responda a los planes institucionales y el Plan Nacional de Lucha Contra la Pobreza y Desarrollo Humano (PNLCP-DH) 2022-2026. De ahí que el propósito de este artículo consiste en describir el proceso de armonización de las carreras de enfermería de la UNAN-Managua. El trabajo investigativo se realizó mediante el enfoque cualitativo. Esta opción metodológica permitió utilizar instrumentos y técnicas que admitieron incidir de manera significativa en los sujetos de estudios de la investigación que, en este caso, fueron los diseños curriculares de las carreras seleccionadas para este estudio, según el área de conocimiento. Entre los principales resultados sobresalen de primero a tercer año, las mismas asignaturas y, es solo en cuarto y quinto año que difieren de asignaturas y estas son mínimas en el área disciplinar. En tanto, la semejanza o igualdad en estas carreras radica en que, en todas las enfermerías (de primero a tercer año), consideran el dominio de los procedimientos de enfermería en función de mejorar las destrezas de sus egresados ya que se promueve la restauración de la salud física.
Enfermedad renal crónica asociada al estrés térmico: una revisión de literatura
Authors: Torrentes Midence Mara Gabriela , Arana Blas Richard David
Published: November 2024

El propósito de este documento de revisión de literatura científica es demostrar la incidencia de la Enfermedad Renal Crónica en los trabajadores del campo provocada por el Estrés térmico. La metodología Prisma, se aplicó a documentos publicados en bases de datos como Google académico, Scielo, Bireme, Lilacs en las cuales se encontraron publicaciones que abordan el tema de estrés térmico en el sector laboral; las publicaciones consultadas fueron de años 2018 a 2023. Es necesario recalcar que la enfermedad renal crónica ha aumentado en sectores laborales con exposición a temperaturas elevadas y que principalmente se da en el campo y áreas de producción (Ruiz Herrera, 2020) . El calentamiento global está provocando un aumento en la exposición a altas temperaturas en ambientes confinados, ambientes internos en áreas de producción y también en ambientes despejados, por lo cual incide directamente en la salud de los trabajadores (OIT, 2023). Como resultado de la revisión se incluyeron 15 artículos sobre seguridad laboral y estrés térmico. Entre las conclusiones de esta revisión se encontró que los trabajadores estudiados se caracterizan por estar expuestos a altas temperaturas sin usar ropa adecuada al ambiente de trabajo o que los proteja de la exposición a rayos ultravioletas y por ende experimentan un aumento del calor corporal, agregado a esto tienen jornadas laborales largas, no toman descansos y no ingieren líquidos adecuados recomendados por un médico laboral o el encargado de higiene y seguridad ocupacional; la incidencia de la enfermedad renal asociada a estrés térmico fue de un 41.9% en el género masculino con una edad de presentación de 46 años, en etapa grado II teniendo como principal factor de riesgo es el estrés térmico de origen laboral.
Valoración económica y ambiental del aporte de la materia orgánica al suelo, mediante el cálculo de nitrógeno disponible, en finca Santa Elisa, municipio de Jinotepe, con proyección en el Triángulo de Oro del departamento de Carazo
Authors: Gaitán Mario José , Arévalo Cuadra Cesar Augusto , Sánchez González Ariel Arístides
Published: November 2024

Para lograr la viabilidad y sostenibilidad de la agricultura es necesario manejar adecuadamente los recursos naturales (suelo, bosque, agua), que permitan el crecimiento económico del sector rural del país (FAO:2015). Este documento presenta la valoración económica y ambiental del aporte de nitrógeno disponible o aprovechable de la Materia Orgánica (MO) del suelo, en finca Santa Elisa, municipio de Jinotepe, con proyección de valoración en el Triángulo de Oro, departamento de Carazo. Los métodos de valoración de bienes y servicios ambientales del suelo, abarcan una variedad de enfoques que buscan cuantificar el valor económico de los servicios que los suelos proporcionan a la sociedad; en esta investigación están relacionados a: - Evaluación de Costo-Beneficio, - Evaluación de Costo-Efectividad, - Valoración Integrada de Ecosistemas y - Enfoques Multicriterio. La valoración parte de los resultados del análisis de suelo realizado en finca Santa Elisa, donde se calculó mediante el porcentaje de materia orgánica presente en el suelo del 12.98 % (Análisis de suelo UNA – LABSA, 2022), la cantidad de nitrógeno disponible, aprovechable en el sistema de producción, que representa al productor ahorro en costos por fertilización nitrogenada, equivalente a 14.89 qq de urea comercial por ha, un beneficio de C$ 19, 350.00 por ha.
A Novel Bi-Directional and Bi-Temporal Delivery System for Enhancing Intrasynovial Tendon Repair
Authors: Chen Yidan , Kinoshita Seth , Yan Emily , Hao Min , Shen Hua , Gelberman Richard , Thomopoulos Stavros , Xia Younan
Published: November 2024

Article
A Novel Bi-Directional and Bi-Temporal Delivery System for Enhancing Intrasynovial Tendon Repair

Yidan Chen 1,, Seth Kinoshita 2,, Emily Yan 3, Min Hao 3,, Hua Shen 4,, Richard Gelberman 4,, Stavros Thomopoulos 5,, and Younan Xia 2,3,*,

1 School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA
2 School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA
3 The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
4 Department of Orthopedic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA
5 Department of Orthopedic Surgery, Department of Biomedical Engineering, Columbia University, New York, NY 10032, USA
* Correspondence: younan.xia@bme.gatech.edu

Received: 24 September 2024; Revised: 8 October 2024; Accepted: 14 October 2024; Published: 18 October 2024

Abstract: Flexor tendon injuries are common and often require surgical repair and prolonged rehabilitation. Successful clinical outcomes depend on the concurrent suppression of adhesions (caused by inflammation) at the tendon surface and promotion of matrix synthesis inside the tendon. Herein, we report a bi-directional and bi-temporal drug delivery system designed to target both the initial inflammatory phase and the subsequent proliferative and remodeling phases of healing to improve outcomes after flexor tendon repair. The system features a multi-layered design with anti-adhesion and pro-matrix factors encapsulated in separate layers of hyaluronate films crosslinked to different degrees to control their direction and rate of release. After validating drug delivery under controlled release, cell culture experiments involving tendon fibroblasts and a Transwell system are conducted to demonstrate the system’s efficacy in modulating local cellular responses. The promising results from this study lay the groundwork for moving this system toward in vivo testing and clinical translation.
Produção científica acerca da saúde indígena no contexto urbano no Brasil: uma revisão de escopo
Authors: Nascimento Tysciana Alice de Brito , Aquino Nádia Alves , Lima Raniele Alana Alves , Viana Adriane Vinhote Moraes , Cerqueira Gabriel Antonio de Lima , Santos Leandra Freitas dos , Souza Luís Paulo Souza e , Martins Fabiana Mânica
Published: November 2024

A produção científica acerca da saúde do indígena que reside na cidade é escassa e abre margem para o englobamento deste no sistema de saúde tradicional, pouco admitindo suas peculiaridades. Objetivo: Analisar a produção científica acerca da saúde indígena no contexto urbano no Brasil. Método: Revisão de escopo. Critérios de inclusão: literatura existente, sem limite temporal, em inglês, português ou espanhol. Critérios de exclusão: estudos duplicados, indisponíveis na íntegra, sem metodologia descrita e estudos fora do eixo temático. Resultados: a busca resultou em 29 estudos, publicados entre 2007 e 2024, sendo 23 quantitativos e 3 qualitativos. Do ponto de vista geográfico, foram encontrados 8 de abrangência nacional, 14 estudos oriundos exclusivamente da região norte e os demais distribuídos entre região nordeste, centro-oeste, Amazônia Legal e Bacia Amazônica. A saúde indígena urbana de forma isolada é alvo de 13 artigos, os demais trabalham os contextos urbano e rural. Conclusão: A produção científica acerca da saúde indígena no contexto urbano é escassa, com concentração na região Norte. A minoria dos estudos trata da saúde indígena urbana de forma isolada, majoritariamente no cenário biomédico da saúde indígena, que também é limitado. Portanto, para melhor entender as condições, diferenças e necessidades dessa população e contribuir cientificamente para futuras pesquisas, é necessário reunir todas as informações relevantes produzidas cientificamente.
Pathways to Emotional Self-Regulation through Mindfulness Meditation: A Mechanistic Study of Positive Psychology Interventions
Authors: Chen Shuxia
Published: November 2024

Background: Mindfulness meditation is increasingly recognized as a technique for enhancing emotional self-regulation. This is done especially through the use of cognitive reappraisal and reduced reliance on expressive suppression. Although there is considerable evidence to encourage hopeful expectations about mindfulness meditationâ€™s benefits to mental well-being, little systematic understanding exists: How does mindfulness work? How does it affect emotional regulation mechanisms and resilience in various populations? Methods: Randomized controlled trial was conducted to investigate how an 8-week mindfulness meditation intervention enhances emotional regulation within 200 participants. Emotional regulation was measured using the Difficulties in Emotion Regulation Scale (DERS) and Emotion Regulation Questionnaire (ERQ). FMRI data offered insights into neural developments associated with the intervention. Repeated measures ANOVA, mediation analyses and regression analyses rounded out data analysis. This multivariable statistical approach lets us examine the direct and indirect effects of mindfulness on emotional control mechanisms. Results: The results showed that participants in the mindfulness group were better able to appraise situations in a positive way, and suffered fewer occasions of suppressing their feelings, than their leading controls. Depending on effect sizes, these changes were from medium to large (p < 0.01). Neuroimaging results revealed an increasingly prefrontal weasiness mixed with declines of amygdala reactivity, indicating to some extent how mindfulness might exert cognitive control and alter emotional reactivity. This further forms the basis for hypothesis tests on mediation paths from cognitive reappraisal via expressive suppression to emotion regulation mechanism and resilience. Conclusion: Mindfulness meditation was found to be a valuable intervention for the improvement of emotional self-regulation. From observed behavior standards down to neurophysiological parameters we found something about its mechanisms in people with an average rather than low income, and universities offering mindfulness courses across countries and continents spread around the world. These findings have application implications for mindfulness in clinical, educational and workplace environments, suggesting that it may promote resilience over a range of characteristics.
Discussion on the Direction of Construction Employment under the Background of Transformation and Upgrading of Construction Industry
Authors: Gan Cuimei , Zhu Hongrui , Gao Lei
Published: November 2024

The construction industry is an important pillar industry of the national economy and one of the main industries of energy consumption. In recent years, the Internet, big data, artificial intelligence and other digital technologies have accelerated innovation, coupled with China 's strong call for ' double carbon ' policies, the transformation and development of China 's construction industry is imperative. Under the guidance of national policies, combined with relevant literature, this paper analyzes the current situation of low-carbon, digital and industrialization transformation and upgrading of China 's construction industry and the demand for talents. Combined with the current development situation of the construction industry, this paper puts forward the employment development path of construction talents under the background of transformation and upgrading from four directions : green building and sustainable development, digitization and intelligence, whole industry chain of prefabricated buildings and international cooperation, and puts forward prospects and suggestions for the future development of construction talents.
Evaluation and Inspiration of “Copyright Statements” in American Museums
Authors: Zou Huimin
Published: November 2024

Under the background of digitalization of collections, in order to avoid copyright disputes, museums and other collection institutions often use a "copyright statements" on their homepage to declare that their collection resources are all belong to themselves. American museums use various methods to restrict public access in practice. Measures such as advocating for "copyright statements" are due to the fact that the collection institutions are fulfilling their management mission, the legal status of digital reproduction copyright is not yet clear, and the cost of open access is also a concern. Analyzing the academic theories and judicial practices of China and the United States, the "copyright statements" ignores the core elements of originality in the recognition of works, as well as the protection period of works. To ensure the effectiveness of the "copyright statements", collection institutions should: improving the differential recognition of digital resource rights; Encourage open access to digital resources; Ensure the stability and openness of digital resources.
The A Study on the Changes in Financial Performance of Shanxi Xinghuacun Fen Wine After Digital Transformation
Authors: Ye Yuting , Guo Xuefei
Published: November 2024

With the continuous development of internet technology, various industries are actively engaging in digital transformation to enhance their competitiveness. Many traditional liquor industries in China are also undergoing digital construction to optimize and adjust their management models and business structures. Taking Shanxi Xinghuacun Fen Wine as an example, this paper studies the changes in financial performance after digital transformation through financial indicators, aiming to make enterprises recognize the impact of digital transformation on their financial performance and continuously improve their digital transformation efforts.
Indian Health Budget 2023 Allocation: Navigating the Framework and Dynamics of Policy Implementation
Authors:   Executive Director, AIIMS Bibinagar Telangana (Hyderabad), India., Bhatia Prof. (Dr.) Vikas , Panda Professor (Asst) Dr. Meely ,   Department of Community Medicine, AIIMS Bibinagar Telangana (Hyderabad), India.
Published: November 2024

India has shown tremendous growth in the last decade as regards to some of the health parameters are concerned. Objective: Overview the previous budgetary heads and allocation and make a comparative analysis of the present years budget disbursement under various heads. Method: The past budget heads and the extent they have transitioned into outcomes based on their objectives have been examined from data sources of the Government of India after a proper search from GoI sites. While highlighting the Bill, it has been made sure to review the existing programs and demonstrate the percent change in budget which has happened over a year. Discussion: Budget snapshot shows that 157 new Nursing Colleges are to be established in colocation with 157 medical collages since 2014, Launch of Sickle cell Anemia Elimination, Joint Public Private Medical Research via select ICMR Labs To promote research in pharmaceuticals, Rs.15000 crores for implementation of Pradhan Mantri PVTG Development Mission over 3 years among others. A comparison of the current Union budget 2023 2024 with the budget of 2021 2022 actuals and the revised budget of 2022 2023 shows a net increase in crores as well as the percent increase in health expenditures as compared to the previous years revised budget [FY 2023] of Rs.9805 crores and 13 Percent respectively. Public Health still needs more focus in terms of greater and better adoption of model rural health centers, mobile medical units, MDRUs, Incubation centers, and Community based Innovations
Effects of Computerised Accounting Procedures on the Quality of Financial Reporting of Crop Boards in Kilimanjaro
Authors:   Department of Economic and Business Studies (DEBS), Mwenge Catholic University (MWECAU), Moshi, Tanzania., Bagege Medani , Mayala Nyanjige ,   Department of Economics and Business Studies, Mwenge Catholic University (MWECAU), Moshi, Tanzania., Amos Amembah A. Lamu ,   Department of Economics and Business Studies, Mwenge Catholic University (MWECAU), Moshi, Tanzania.
Published: November 2024

In todays technological world, the use of computerized accounting procedures has become increasingly prevalent across various organizations. Computerized accounting procedures have been employed by organizations for financial record keeping and reporting. Financial reports are an essential source of information needed for different decision makers and other stakeholders. Therefore, this study aimed to establish the effects of computerised accounting procedures on the quality of financial reporting of crop boards in Kilimanjaro region, Tanzania. The study was grounded by Resource-Based View (RBV) developed by Barney in the 1990s. The study applied a descriptive research design under quantitative research approach. Eight (8) crop boards in Moshi Municipality were targeted comprising of Forty (40) staff dealing with accounting and finance. Sample size was obtained through Sample Size Calculation for Finite Population. Data was collected through questionnaires. Face and content validity was used to ensure the validity of the research instruments, and then the instruments were piloted Three (3) accounts and finance employees at Tanzania Coffee board to clarify any ambiguities and checked for consistency of the data to be collected. Reliability was ensured through Cronbachs alpha test which was run through Statistical Package for Social Sciences (SPSS) and obtained a coefficient of 0.81 which is reliable. Data was analysed through the aid of SPSS and then presented in form of tables, frequencies, percentages and means. Ethical considerations and ethics ethical values were adhered throughout the research process. The study found that computerized accounting procedures had effects on the quality of financial reports of Crop boards in Kilimanjaro region, Tanzania. Basing on the findings it was concluded that the computerized accounting procedures have a positive effect on the quality of financial reporting of Crop Boards in Kilimanjaro. Further, it was concluded that computerized accounting procedures were effective in facilitating decision making and improving the overall quality of financial reporting. This study recommended that Crop Boards in Kilimanjaro should continue using computerized accounting procedures and enhance the system for improved efficiency, accuracy, and accessibility of financial data. Further, it is recommended that Crop Boards should provide training and skill development programs to their accountants. Also, this study provides area for further studies, recommending that further studies could be conducted on the influence of Computerized accounting systems on the Financial Decision Making.
Effects of Reduced Cash Flows on Cash Management for Tourism Companies During COVID-19 Pandemic in Kilimanjaro Region, Tanzania
Authors:   Department of Economics and Business Studies, Researcher and Consultant, Mwenge Catholic University (MWECAU), Tanzania, East Africa., Megewa CPA Samson Chacha , Mayala Dr. Nyanjige M. ,   Department of Economics and Business Studies, Senior Lecturer, Researcher and Consultant, Mwenge Catholic University (MWECAU), Tanzania, East Africa., Minja Dr. Gileard ,   Department of Agriculture, Earth and Environmental Sciences, Researcher and Consultant, Mwenge Catholic University (MWECAU), Tanzania, East Africa.
Published: November 2024

The COVID-19 pandemic affected businesses and organizations in their daily operations. Tourism businesses were the most affected, especially in countries whose economies are dependent on the tourism sector. This study sought to assess the effects of reduced cash flows during the COVID-19 Pandemic on cash management as part of the working capital management practices of the tourism companies in the Kilimanjaro region of Tanzania. The study was informed by the Cash conversion cycle (CCC) theory. The population for the study was 67 staff members of the selected three companies (Zara Tours, Asante Tours, and Monkey Adventures) under investigation in the finance and procuring departments. The study used a sample of 67 respondents determined by census techniques as the population was small, commanding the entire population to be a sample size. Both quantitative and qualitative data were collected. Tool validity was ensured using content validity, the literature related to cash flow management, and a discussion with the research supervisor. Reliability was tested using the Cronbach alpha coefficient, where a value of 0.733 was obtained. Data were collected using a structured questionnaire and key informant interview guide. Descriptive statistics and inferential statistics were both used for data analysis. The study found that changes in cash flows affected cash management for the three tour companies in the study area, which were statistically significant at p values less than 0.05. Specifically, the findings show that the effects of the COVID-19 pandemic such as reduced cash flows complicated cash management in the operations. It is concluded that reduced cash flows during the pandemic were disrupted, resulting in cash management difficulties. It is recommended that, tourism companies enhance their supply cost management strategies as well as maintain healthy cash management.
Ask yourself for help: a review of objective evidence on Autonomous Cognitive Instant-Engagement regulating the circadian rhythm
Authors: Liu Yutong
Published: November 2024

Disruptions in circadian rhythms and their detrimental effects on physical health have become deeply ingrained in daily life. Traditional treatments, such as pharmacotherapy, electromagnetic therapy, and cognitive behavioral therapy, have each explored their own paths but still possess structural limitations, particularly for those who are reluctant to seek treatment for rhythm disorders. "Autonomous Cognitive Instant-Engagement" can be viewed as a new therapeutic approach. It acknowledges the potential of autonomous, immediate cognitive engagement to have an immediate impact on the body and regulate circadian rhythms. However, this concept has not received sufficient attention because cognition as a zeitgeber (time-giving factor) has been under-discussed in the past. This article reviews existing literature on the objective evidence for "Autonomous Cognitive Instant-Engagement" in regulating circadian rhythms and discusses its potential mechanisms and future directions.
Frequency and Demographic Profile of Odontogenic Cysts Diagnosed at Tripoli University Hospital, Libya
Authors: Asmaa Shanab  , Dunya Ben Sofia  , Sarah Shanab
Published: November 2024

Odontogenic cysts are a group of lesions that exclusively affect the oral and maxillofacial regions. The current study aimed to determine the relative frequency and demographic features of odontogenic cysts diagnosed histologically at Tripoli University Hospital and to compare our findings with the latest reports. A 22-year retrospective study of odontogenic cysts histologically diagnosed at Tripoli University Hospital, Tripoli, Libya, archived from 2002 to 2023 was performed. Demographic data including, gender, age at diagnosis, location of lesion, and histopathological diagnosis, were collected and analyzed retrospectively. The diagnosis was according to the latest criteria of the 2022 World Health Organization classification. Odontogenic cysts constituted 9.7% of all 2334 registered orofacial biopsy specimens. A total of 227 cases of histologically diagnosed odontogenic cysts were analyzed. Of these, 129 (56.8%) were inflammatory cysts and 98 (43.2%) were developmental cysts. Apical radicular was the most common type of cyst (54.2%), followed by dentigerous cyst (31.3%), and odontogenic keratocyst (5.3%). A slight male predilection was observed with an overall male-to-female ratio of 1.2:1. The age range was from 5 to 85 years with an overall mean age of 33 ± 15.16 years. The peak incidence was in the third and fourth decades of life. The posterior regions of the jaws were the most prevalent sites (34.4%) for all studied cysts. The demographic profile of the odontogenic cysts in this cohort is similar to previous reports in Libyan and other worldwide populations.
Modelling the risks of Nymphoides peltata spread in Swedish lakes
Authors: Weldon James
Published: November 2024

Species distribution modelling is a valuable tool for identifying areas most at risk of the spread of potentially harmful species. Here we model the environmental factors governing the distribution of a harmful species of concern that is currently found in Sweden at only a limited number of locations: the aquatic macrophyte N. peltata (sjögull). The most important factors determining risk of establishment are water chemistry (sufficient amounts of calcium is required), temperature (the species is partly limited by colder temperatures in Sweden) and connectivity to other water bodies. The results how that there are potentially a large number of lakes in mid to southern Sweden where N. peltata could establish populations, with undesirable consequences for biodiversity and recreation.