bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Model Penerimaan Teknologi Termodifikasi Pada Persepsi Jarak Sosial, dan Persepsi Jarak fisik
Authors: Pamuji Agus
Published: April 2023

Technology acceptance models continue to change with modifications. In this study, two new aspects will be included, namely social distance and physical distance as factors that can influence the acceptance and use of information technology, especially using social media. These two factors are considered essential. Besides that, in essence, these two factors are still under the social influence that has been widely studied. However, if social influence tends to have a subjective element so that it is related to subjective norms, then the perception of social distance and physical distance is an influence from the environment in addition to subjective norms. This study uses theoretical study methods and tracing various sources that will be included and produce new models. Thus, the perception of social distance and the perception of physical distance become a modified TAM model.
Pemanfaatan Teknologi Artificial Intelligence untuk Penguatan Kesehatan dan Pemulihan Ekonomi Nasional
Authors: Astuti Fitri Andri
Published: April 2023

Technological developments have been used to support health and economic systems in various countries. Especially during the COVID-19 pandemic, in the health sector, for example, starting from the process of identifying positive cases with chatbots, contact tracing, monitoring independent isolation, even monitoring social media for mental health can be done with the help of technology. This can help the government make policies and keep health workers in direct contact with patients, especially patients with mild symptoms, for patients with severe symptoms can be prioritized to be assisted by health workers. In the economic field, this pandemic has caused economic growth to decline, even in the third quarter of 2020 Indonesia experienced negative economic growth. The largest proportion of economic growth in Indonesia is household consumption, which is closely related to people's purchasing power. Artificial intelligence technology can be used to examine the level of public consumption. So that it helps the government in making policies on how to increase people's purchasing power. The use of this technology involves a variety of devices, online datasets, devices connected to the internet (IoT), and advances in the fields of machine learning, computer vision and natural language processing. This study aims to provide an overview of how artificial intelligence technology has great potential in strengthening the health system and restoring the national economy.
Sistem Klarifikasi Bahasa Isyarat Indonesia (Bisindo) Dengan Menggunakan Algoritma Convolutional Neural Network
Authors: Arisandi Lukman , Satya Barka
Published: April 2023

Communication is needed to interact and socialize in order to connect with the environment and other people. In general, communication uses spoken or written words. However, in some cases in the community there are some people who cannot communicate verbally due to physical limitations such as deaf and speech impaired. Usually, they use nonverbal communication such as body movements and this communication is commonly referred to as sign language. The sign language method is used to spell or pronounce words. However, not everyone can understand the sign language used by the deaf and mute, so a system or tool is needed to bridge communication between the deaf or mute and normal people. One solution that can be offered is the use of computer technology as a tool to identify sign language. The technology is in the form of an automatic language translator system design with processing input images in the form of letter classes A to E, I, You and I Love You using the Convolutional Neural Network (CNN) architecture which by using this method the accuracy value can reach 99.82%.
WHEN THE WHOLE WORLD, STARTING FROM DECEMBER 2019, IS CONCERNED ABOUT THE "CORONAVIRUS" -COVID-2019, HOW CAN BIOPHYSICS HELP?
Authors:   Samarkand State Medical University, Uzbekistan, N. O. Sodikov , Z. A. Muminova ,   Tashkent Chemist - Technological Institute, Uzbekistan, D. Khasanova ,   Samarkand State Medical University, Uzbekistan
Published: April 2023

This paper analyzes modern methods and technologies for diagnosing and treating patients with coronavirus. And so, when the coronavirus settles in the endothelial cells (the inner wall of the blood and lymphatic vessels), a thrombus (thrombosis) is created. Thrombosis - intravital formation of blood clots (thrombi) inside the blood vessels, preventing the free flow of blood through the circulatory system.
INCREASING ATTENTION TO SANITARY AND HYGIENIC CONDITIONS AND THE ENVIRONMENT IN THE AREA OF ECOTOURISM FACILITIES
Authors:   Trainee Teacher Bukhara Engineering And Technology Institute Uzbekistan, Fazliddinovich Rakhmonov Gayrat , Toyirovich Usmonov Erkin ,   Assistant Bukhara Engineering And Technology Institute, Uzbekistan
Published: April 2023

In the modern rapidly developing era, environmental pollution, an excessive increase in household and technical waste are among the pressing problems that concern the population of the whole world. This has a serious impact on human health, as well as the disappearance of all living beings and flora and changes in genetics. Naturally, the main cause of damage to this planet is man. Although we cannot completely stop this situation, we can do our part to prevent pollution of nature.
USE OF NEW INNOVATIVE METHODS IN MOTHER LANGUAGE TEACHING
Authors:   A Student Of The Faculty Of Arts, Nukus Branch, Uzbekistan State Institute Of Art And Culture, Uzbekistan, Kizi Seydullaeva Bibiayim Erejep , Qdirbaevna Abdazova Urziya ,   A High-Class Teacher Of Karakalpak Language And Literature, General Education School No. 16 Of Khojayli District, Republic Of Karakalpak Stan, Uzbekistan
Published: April 2023

This article talks about the widespread use of innovative methods in the learning and teaching of the mother tongue in the educational system, which is covered by new technologies, and their significant effect.
THE RELATIONSHIP BETWEEN EMOTIONAL INTELLIGENCE AND SUCCESS IN INTEGRATED LANGUAGE SKILLS IN SLA
Authors:   Department Efl Teacher, Kimyo International University In Tashkent English Language, Uzbekistan, Izzatillayevna Juraeva Shakhzoda
Published: April 2023

The current article aimed to reveal the correlation between cognition of Emotional Intelligence (EI) and stances of achieving success in second language learning. It is obvious that EI plays a major role for ESL learners in language learning. However, one of the research questions of the present article is that “How EI may impact on learners’ development in a language learning process, positively or negatively?”
CONSULTATION FOR EDUCATORS "DEVELOPMENT OF COHERENT SPEECH IN OLDER PRESCHOOL CHILDREN"
Authors:   Gulistan State University Faculty Of Pedagogy 2nd Year Student, Uzbekistan, Kizi Bakirova Umida Bakhtiyor
Published: April 2023

The work on the sound culture of speech in the senior preschool age is aimed at solving the problems of cultural and speech education and at preparing preschoolers for literacy. Work continues on the formation of phonemic hearing, children's awareness of the sound composition of the word, the formation of phonemic perception of the word.
SPECIFIC CHARACTERISTICS OF PRIVATE BUSINESS DEVELOPMENT
Authors:   Phd, Head Of Department Of The “Economics”, Associate Professor Namangan Institute Of Engineering Technology, Uzbekistan, Rashidov Rahmatullo A. , Salokhiddinov Zuhruddin N. ,   Master Student, Namangan Institute Of Engineering Technology, Uzbekistan
Published: April 2023

As soon as possible, using the experience of all developed countries in the world, especially the examples of Turkey, South Korea and a number of other Asian countries. the need to transition to a market economy without causing great damage to any class of the population formed the content of the state policy. For this purpose, wide-ranging economic reforms were planned, and the following theoretical bases and criteria for the transition to market relations in the republic were determined: the economy should be free from ideology and its priority over politics; being the main reformer of the state; priority of laws and compliance; conducting a strong social policy aimed at the interests of the people; a gradual, step-by-step transition to a market economy.
STUDY OF ACUTE TOXICITY AND ANTITUMOR ACTIVITY OF NEW COLCHAMETIN PREPARATION СOLCHAMETIN
Authors:   Samarkand State Medical University, Uzbekistan, Javlonabduraimovich Yuldashev , Narzikulovich Ibragimov Shavkat ,   Republican Specialized Scientific And Practical Medical Center Of Oncology And Radiology Of The Ministry Of Health Of The Republic Of Uzbekistan, Shavkatovna Shakhanova Shakhnoza ,   Samarkand State Medical University, Uzbekistan, Sobirovna Esankulova Bustonoy ,   Samarkand State Medical University, Uzbekistan
Published: April 2023

The aim of the study was to study acute toxicity in different methods of administration in mice and rats of a new antitumor preparation "colchametin" (K-2) and its antitumor activity on 2 strains of tumors Material and research methods. Acute toxicity of the preparation K-2 with a single intraperitoneal administration was carried out according to the Litchfield and Wilcoxon method in 60 white infertile mice weighing 202g. both sexes and 60 male and female rats weighing 14010g 5 animals in each group, a total of 120 mice and rats were used. The study of antithumor activity was performed on 12 non-fertile and 16 linear mice with transfused tumors S-180 and ACATON, which was injected with preparations on the 4th day after tumour was administered on day 4 after tumour transfusion 10 times. Evaluation of the results was carried out according to standard criteria: inhibition of tumor growth (SRW), body weight and spleen of animals. Differences at p < 0.05 were considered reliable. Results. Such data at single vnutribryushinny introduction are obtained to mice: the average lethal dose of LD50 makes 890 (-150+172) mg/kg, At oral introduction of medicine K-2 to mice of LD50 is equal to 3250 (-630+650) mg/kg, LD50 at single vnutribryushinny to rats of medicine K-2 LD50 makes 410 (-56+61) mg/kg, LD50 at single oral introduction to rats makes 3250 (-630+650) mg/kg, are defined also at all ways of introduction of LD10, LD16 and LD84 value The antitumor activity of the drug K-2 on the tumor strain of Sarcoma 180 was high - about 99/90%. On the ACATON tumor, the K-2 effect during intraperitoneal administration was lower and reached 76/75%, however, its effect on both tumors was accompanied by a decrease in hematopoietic indicators. Conclusions. The study of the acute toxicity of the substance of the preparation K-2 showed that this preparation belongs to class IV of low-toxic compounds. On 2 tumors, the effect of the new drug was high, but hematopoietic indicators were reduced.
STUDY OF THE NATURE OF COUGH IN VARIOUS FORMS OF TUBERCULOSIS AND CHRONIC NONSPECIFIC LUNG DISEASES
Authors:   Assistant Of The Department Of Infectious Diseases And Childhood Infection Phthiziatriya And Pulmonology, Uzbekistan, Nikolaevna Mukhteremova Vera , Alekseeyevna Aminova Asalya ,   4th Year Medical And Pedagogical Faculty Student Tashkent Pediatric Medical Institute Tashkent, Uzbekistan
Published: April 2023

The purpose of this study was to investigate the nature of cough in patients with different types of tuberculosis (TB) and chronic nonspecific lung diseases (CNSLD). A total of 120 patients were selected from the outpatient department of a tertiary care hospital in Tashkent, Uzbekistan, between September 2019 and December 2021. Cough nature was assessed by recording its duration, frequency, intensity, and associated symptoms. The results showed that patients with TB had a higher frequency and intensity of cough compared to those with CNSLD. Patients with pulmonary TB had a longer duration of cough compared to those with extrapulmonary TB. Patients with TB also reported more symptoms such as hemoptysis and fever. The findings suggest that a thorough assessment of cough nature in patients with TB and CNSLD can help in the early diagnosis and management of these diseases.
PRINCIPLES OF SURGICAL TREATMENT OF TRACHEAL STENOSIS
Authors:   Assistant Of Department Of General Surgery No.2, Tashkent Medical Academy, Tashkent City, Uzbekistan, Rafiqovich Zokhirov Adkhamjon , Ogli Otamirzayev Qudrat Abdujabbor ,   Assistant Of Department Of Faculty And Hospital Surgery, Transplantation No.2, Tashkent Medical Academy, Tashkent City, Uzbekistan
Published: April 2023

To correctly carry out modern surgical treatment measures of advanced scar stenosis after endotracheal intubation and to give conclusions on the method carried out in them, to prevent various complications arising after the operation method, the specifics of the method to provide information about the advantages and disadvantages, as well as modern laryngotracheal stents that are used today.
SPATIAL DEVELOPMENT OF STUDENTS' IMAGINATION IN ENGINEERING GRAPHICS BY SOLVING PROBLEMS RELATED TO DESIGN
Authors:   Associate Professor, Tspu Im. Nizami, Head Of The Department, Uzbekistan, Erpolotovich Tashimov Nurlan , Barat Kyzy Tukhtakulova Zebiniso ,   Master's Student Of The Pedagogical Institute Of Karshi State University, Uzbekistan
Published: April 2023

This article discusses ways to develop students' spatial imagination by performing graphic tasks that include design elements in engineering graphics.
PRACTICAL APPLICATION OF GEOMETRIC CONSTRUCTIONS IN SOLVING POSITIONAL TASKS IN THE PERSPECTIVE
Authors:   Associate Professor Of The Department Of Engineering And Computer Graphics, Tashkent State Pedagogical University, Uzbekistan, Valiyev Azamjon Nematovich
Published: April 2023

The perspective image from the execution is used in practice in architecture, fine art, in design and reconstruction works. Checking the positional-metric relations between geometric figures in perspective requires a person to have a strong spatial imagination and thinking, logical thinking. There are certain difficulties in teaching such questions and understanding them by students. This article describes the content of positional questions on which perspective is taught, their types and practical significance, the place that perspective occupies in the execution of the image. The article mainly discusses methods for solving positional problems using geometric constructions.
THE CONCEPT OF EXISTENCE OF THE LEXEME – “OLMAK” ON THE ANALYSIS OF THE FUNCTION OF THE FORMATIVE VERB IN TURKISH
Authors:   Teacher, Tashkent State University Of Oriental Studies, Uzbekistan, Davlatov Zoirjon Zokiraliyevich
Published: April 2023

The concept of existence of the lexeme- olmak provides information about the analysis of the function of the formative verb.
POSTMODERN ELEMENTS IN ORHAN PAMUK'S NOVEL “MY NAME IS RED”
Authors:   Teacher, Tashkent State University Of Oriental Studies, Uzbekistan, Asadova Dilbarkhon
Published: April 2023

This scientific article reveals the postmodern elements in the novel "My name is red" by Orhan Pamuk, one of the leading representatives of Turkish postmodern literature. The main idea of the work is to end the conflict between Eastern and Western cultures and to harmonize the two with each other. In the novel "My name is red", Orhan Pamuk skillfully uses the elements of detective fiction, East-West conflict in art, and melodrama in terms of the processing of old motifs and the development of events. The article emphasizes that the novel "My Name is Red" is a detective fiction and a love story. The novel tells about the colorful world of miniaturists, which is divided by East-West conflicts and is also the scene of fierce debates. The composition of the novel and the way of looking from a polyphonic point of view determine the individual style of the novel. The novel "My name is red" is a novel comprising 59 chapters, which analyze the paradoxes and parallels between history and today through the lives of various people, and reflect the complex reality. If we compare the novel "My name is red" with other novels by Orkhan Pamuk in a postmodern spirit, this novel can be called a novel full of deep symbols, diverse characters and a chain of interesting events. The novel differs from Pamuk's other novels by its comprehensive themes such as situations, characters, their inner world, ordinary and scary dreams, sexual desires, history, art, and crime. At the same time, this work can be considered a historical, romantic-adventure, and detective novel.
SIGNIFICANCE OF CLUSTER IN INCREASING COMPETITIVENESS IN THE REGION
Authors:   Lecturer, Mamun University Non-State Educational Institution, Uzbekistan, Abdikarimova Zilola
Published: April 2023

In the conditions of the development of the market mechanism, the problem of competitiveness arises sharply, and its solution forces all market subjects to actively search for methods and ways to increase competitiveness. In this regard, it is necessary to increase competitiveness and strengthen one's position in the market in order to obtain maximum income. The experience of many countries shows that clusters allow the economy to achieve high efficiency, thereby ensuring competitiveness and increasing the well-being of the population. The formation of clusters allows for more complete use of the resources and advantages available in the country.
SOCIO-HISTORICAL ROOTS OF SOCIO-POLITICAL REFORMS IN THE PEOPLE’S REPUBLIC OF CHINA
Authors:   Candidate Of Political Sciences, Associate Professor Researcher Of Tashkent State University Of Oriental Studies, Uzbekistan, Shazamanov Sh. I.
Published: April 2023

The article is devoted to the study of China's development in the first half of the 19th and 20th centuries. China's confrontation with Western culture, which is more advanced than itself in the social and cultural spheres, from the 19th century, the reasons for China's involvement in the world economy, the gradual development of Chinese reforms, etc., are discussed.
Titanium-containing functional materials from natural raw materials and technogenic waste
Authors:   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Gerasimova Lidia G. , Shchukina Ekaterina S. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Nikolaev Anatoly I. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences
Published: April 2023

Natural mineral raw materials, as a rule, have a complex composition. Its processing with the release of one or two components is accompanied by the formation of a large amount of waste, including man-made, which is harmful to the environment. In this regard, the problem of its complex processing is important and remains relevant in setting the directions of scientific research to improve existing and development of new technologies.
Obtaining heat-resistant ceramics based on various natural and synthetic materials
Authors:   Belarusian State Technological University, Dyatlova Evgenia M. , Panteleenko Fedor I. ,   Belarusian National Technical University, Popov Rostislav Yu. ,   Belarusian State Technological University, Samsonova Alexandra S. ,   Belarusian State Technological University
Published: April 2023

The paper presents the results of studies of the possibility of obtaining heat-resistant ceramic products based on natural clay raw materials of the Republic of Belarus of various mineral composition, Onotsky talc, as well as synthetic alumina-containing components. The processes occurring during the synthesis of ceramics for technical purposes, the change in the phase composition and properties of the material during heat treatment have been studied. The conditions for obtaining a heat-resistant material, as well as the parameters of its operation, are determined. On the basis of the obtained experimental data, laboratory and industrial tests, the prerequisites for organizing the production of heat-resistant ceramics in the Republic of Belarus based on domestic clay raw materials have been created.
Features of proton transport in BaLa0.9M0.1InO4 (M = Nd, Gd, Pr) and BaLaIn0.9M0.1O4 (M = Sc, Y) doped perovskites based on barium lanthanum indate
Authors:   Institute of High Temperature Electrochemistry UB RAS, Egorova Anastasia V. , Belova Ksenia G. ,   Institute of High Temperature Electrochemistry UB RAS, Bedarkova Anzhelika O. ,   Institute of High Temperature Electrochemistry UB RAS, Animitsa Irina E. ,   Institute of High Temperature Electrochemistry UB RAS, Tarasova Nataliia A. ,   Institute of High Temperature Electrochemistry UB RAS
Published: April 2023

The paper discusses the features of proton transport in isovalently doped layered perovskites based on barium-lanthanum indate BaLaInO4. The effect of the nature and concentration of the dopant on the unit cell size, water absorption, and proton conductivity was estimated. It is shown that the doping of the cationic sublattices of the layered perovskite BaLaInO4 with Nd3+, Gd3+, Pr3+, In3+, Y3+ ions makes it possible to increase the proton conductivity up to ~ 2 orders of magnitude, and the complex oxides obtained by this method are promising from the point of view of their further study as a material for a proton-conducting solid oxide electrolyte fuel cell.
Chemical enrichment of substandard beryllium concentrates
Authors:   B. N. Laskorin Leading Research Institute of Chemical Technology “VNIIНT”, Menshikov Valentine V. , Matyasova Valentina E. ,   B. N. Laskorin Leading Research Institute of Chemical Technology “VNIIНT”, Solntseva Ekaterina B. ,   B. N. Laskorin Leading Research Institute of Chemical Technology “VNIIНT”
Published: April 2023

Global trends in the use of beryllium in the creation of high-tech products dictate the need to create beryllium production in Russia. The prerequisites for this are the availability of a raw material base and competencies in the field of technology for the production of beryllium metal and products based on it. The most promising are the ores of the Malyshevsky deposit (JSC "Mariinsky Mine"), with an ore content of 0.12–0.14 % according to BeO, the approved reserves of which will last for 30–50 years of uninterrupted mining. As a result of exploratory research on the chemical enrichment of 5 % BeO flotation concentrate, a basic technological scheme was developed, and a high-grade concentrate with a BeO content of more than 10 % was obtained. Solving the problem of obtaining high-quality concentrate will solve a complex of problems in the raw material — technology — production of beryllium metal and products based on it.
The industrial pollutants biodegradation of using aspergillus niger strains
Authors:   Kazan National Research Technological University, Mindubaev Anton Z. ,   Innovative Technologies of Detoxification, Minzanova Salima T. ,   Tatar Research Institute of Agricultural Chemistry and Soil Science — Subdivision of the Federal Research Center “Kazan Scientific Center of Russian Academy of Sciences”, Babynin Edward V. ,   Institute of Organic and Physical Chemistry named after A. E. Arbuzov, Mironova Lubov’ G. ,   Institute of Organic and Physical Chemistry named after A. E. Arbuzov, Badeeva Elena K. ,   Institute of Organic and Physical Chemistry named after A. E. Arbuzov
Published: April 2023

For fourteen years our team has been working on the research of biodegradation, primarily of phosphorus-containing compounds. The world's first biological detoxification of elemental — white and red — phosphorus was carried out. We obtained mold fungi cultures, which transform a substance of the first hazard class white phosphorus into harmless phosphate. This is the first example of the inclusion of white phosphorus into the biospheric cycle of the phosphorus element. In the future, the results of the research may become the basis for effective methods of preventing and eliminating pollution by toxic phosphorus compounds. Therefore, the research is of interest both for practical application and from the point of view of fundamental science.
Saccharina japonica - its technochemical characteristics for use in the technology of food, therapeutic and prophylactic products
Authors: Podkorytova Antonina , Roshchina Anna , Kotelnikova Lilia , Rodina Tatiana
Published: April 2023

Data are presented that determine the directions of processing and use of brown algae, including the hydration coefficient (HC) of dried thalli or crushed into pieces of various sizes, which is an important indicator used in setting the parameters of technological processes, as well as the yield of finished products. The results are presented demonstrating the ability of the dried algae Saccharina japonica to limit hydration. It has been shown that during deep treatment of S. japonica in order to increase the HC, about 80% of biologically active substances are lost, with the exception of fiber, some part of the protein, the organic form of iodine, as well as alginates associated with polyvalent metal cations in water-insoluble complexes with alginic acids. It was determined that when soaking dried S. japonica in water, the relative content of alginic acid increases, while the HC of kelp also increases. It has been established that HC equal to 20-26 corresponds to a significant removal of extractive biologically active substances (BAS) from S. japonica. At HC 14-16, up to 50% of biologically active substances remain in the tissues of algae, giving taste to kelp algae and their biological value. It has been shown that with the content of biologically active substances in algae up to 50% of the initial value, a real opportunity is created to obtain food, therapeutic and prophylactic products from dried S. japonica.
Effects of Cassava Wastewater on Opa Stream in Ile-Ife, Nigeria
Authors: Jeje J.O.
Published: April 2023

This study is aimed at determining the impacts of indiscriminate disposal of cassava wastewater into the nearby stream. The cassava wastewater quality was tested in accordance with the standard methods for the examination of water and wastewater for both physical and chemical parameters such as temperature, conductivity, hardness, pH and turbidity. The physicochemical properties of both water and cassava wastewater was conducted before and after the disposal of the cassava wastewater and the result of the experiments showed that the effluent is acidic with pH of 3.8 and of high conductivity of 40 µs/cm2. The cyanide content is also very high with 11.88 mg/kg as compared to 1.5-3.5 mg/kg recommended by WHO. The total solids, and total suspended solids are also in high range of 2000 mg/kg and 3000 mg/l respectively. Its hardness is 800 mg/l, chloride 2000 mg/l. The dissolved oxygen was not detected. The physicochemical properties of the after experienced significant difference (p<0.05).
Экспрессия LIF у женщин с повторными неудачами имплантации и хроническим эндометритом
Authors: Аскар Е. , Рыбина А.Н. , Абшекенова А.Т. , Локшин В.Н. , Карибаева Ш.К. , Валиев Р.К.
Published: April 2023

Актуальность: В последние годы наблюдается особый интерес к хроническому эндометриту (ХЭ), так как данная патология является возможной причиной бесплодия, привычного невынашивания и повторных неудач имплантации (ПНИ). Одной из существенных причин снижения фертильности и неудачных попыток ВРТ является недостаточная эндометриальная функция, обусловленная изменениями структуры самого эндометрия, наступающими чаще всего в результате воспаления. На сегодняшний день бесплодие, ассоциированное с ХЭ, является актуальным предметом исследования в области репродуктологии. Цель исследования – изучить влияние комплексного лечения хронического эндометрита у женщин с повторными неудачами имплантации на экспрессию лейкемия-ингибирующего фактора в период «окна имплантации».Материалы и методы: Проведено ретроспективное когортное исследование, в которое вошли 88 пациенток с ПНИ, которым была сделана диагностическая офисная гистероскопия с биопсией эндометрия в пролиферативную фазу менструального цикла, на 6 день приема прогестерона или на 7 день после пика лютеинизирующего гормона с гистологией эндометрия, в «Международном клиническом центре репродуктологии PERSONA» с января 2021 по сентябрь 2022 г.Результаты: После проведенного комбинированного лечения хронического эндометрита экспрессия CD 138+ после лечения достоверно снизилась (0,941±0,176 против 8,02±1,25, p = 0,0001), а экспрессия лейкемия-ингибирующего фактора (LIF) – достоверно повысилась (6,53±1,56 против 4,56±0,67, p < 0,001). По результатам контрольной биопсии в 74,5% случаях ХЭ не был выявлен, а у 25,5% пациенток отмечена персистенция ХЭ. Заключение: ХЭ является причиной неудач имплантации в связи с нарушением рецептивности в период окна имплантации. Результаты данного ретроспективного исследования показывают взаимосвязь между ХЭ и нарушением рецептивности эндометрия, что может приводить к неудачным попыткам ВРТ. Аномальная экспрессия LIF в эндометрии может быть одной из причин неудач имплантации.
Los retos de la modalidad virtual en la enseñanza en tiempo de covid-19, en los estudiantes de licenciatura de mercadotecnia, de la facultad de ciencia económicas y administrativas, extensión, Sinaloa de Leyva
Authors: Urías Rivas María Oralia
Published: April 2023

El artículo tiene como objetivo conocer los retos de la modalidad virtual en la enseñanza en tiempo de Covid-19 en los estudiantes de Licenciatura de Mercadotecnia, de la Facultad de Ciencia Económicas y Administrativas, Extensión, Sinaloa de Leyva, Por lo tanto los resultados encontrados fue el desconocimiento que tuvieron que enfrentar los estudiantes en las clases virtuales en relación al uso de la tecnología de las plataformas Moodle, Zoom, Google Classroom, Google Meet, y redes sociales como el WhatsApp y correos electrónicos, Así como la situación económica para adquirir los dispositivos utilizados para recibir la enseñanza en línea como; laptop, computadora de escritorio, tabletas, teléfonos inteligentes, dificultad con la señal de internet y carga excesiva de tareas, mala comunicación, poca empatía y flexibilidad con algunos docentes, provocando dificultades en los estudios. Otros desafíos fueron la necesidad de desarrollar el autoaprendizaje, la autonomía y las emociones en relación al aprendizaje a distancia. La metodología utilizada es el enfoque mixto, donde el estudio fueron exploratorio, descriptivo y fenomenológico, aplicando muestras no probabilísticas por conveniencia, empleando la técnicas cualitativa y cuantitativa e instrumentos de investigación como la observación, la entrevista y el cuestionario que ayudaron a obtener información.
PENINGKATAN SITOKIN INTERFERON GAMA TIKUS WISTAR SETELAH DIBERIKAN EKSTRAK ETANOL BUAH Etlingera rubroloba A.D. Poulsen SEBAGAI IMUNOSTIMULATOR
Authors: Ilyas Y. Muhammad , Fadhliyah Malik  , Wahyuni  , Asriullah Jabbar  , Faradilla  , I Sahidin  , Nurhikma
Published: April 2023

Etlingera rubroloba A.D. Poulsen (E. rubroloba) merupakan tumbuhan endemik di Sulawesi Tenggara, dan secara empris oleh masyarakat etnis Wawonii digunakan untuk menyembuhkan demam tifoid dan meningkatkan daya tahan tubuh (imunostimulator), secara ilmiah terbukti meningkatkan aktivitas fagositosis sel makrofag sehingga berpotensi dikembangkan sebagai imunomodulator alami. Tujuan penelitian yaitu mengetahui efek imunostilator ekstrak etanol buah E. rubroloba dengan, mengukur peningkatan kadar Interferon gama (IFN-?) pada tikus wistar. Metode penelitian ini yaitu eksperimental menggunakan 24 tikus wistar jantan, dibagi dalam 6 kelompok perlakuan yaitu ekstrak dosis 200, 300, 400 (mg/kgBB), kontrol positif (ekstrak meniran komersil), kontrol pelarut (Na.CMC 0,5%), dan kontrol normal. Perlakuan diberikan secara peroral setiap hari, selama 7 hari, hari kedelapan hewan uji diinfeksikan secara intraperitonial bakteri Staphylococcus aureus. Kadar IFN-? dianalisis dengan metode Elisa sandwich, dan data diuji statistik dengan ANOVA satu arah. Penelitian ini memberikan hasil bahwa, perlakuan ketiga dosis ekstrak etanol dari buah E. rubroloba berefek sebagai imunostimulator, dengan meningkatkan  kadar IFN-?, dan secara statistik berbeda bermakna terhadap kontrol pelarut (p<0,05), sehingga tumbuhan ini menjadi salah satu alternatif agen imunomodulator dari alam yang dapat dikembangkan.
 Kata Kunci : Buah Etlingera rubroloba, ekstrak etanol, Interferon gama,  Imunodulator, tikus wistar.
OPМAН OPНAЛACТЫPУДЫҢ AҚПAPAТТAPЫН ӨҢДEУ ЖӘНE ЖAҢAPТУ
Authors: Мудетбек А.Б. , Мырзабаева Г.А. , Абаева К.Т. , Шыныбеков М.К. , Орайханова А.А.
Published: April 2023

Орман қорының мемлекеттік есебі Қазақстан Республикасының заңдарында белгіленген тәртіппен орман қорыны күзетілуін, қорғалуын, ормандардың молықтырылуы мен орман өсіруді, орманның пайдалануын, орман қорының сандық және сапалық өзгерістеріне жүйелі бақылау жасауды ұйымдастыру және мемлекеттік органдарды, мүдделі жеке және заңды тұлғаларды орман қоры туралы ақпаратпен қамтамасыз ету үшін жүргізіледі. Қaзaқcтaндa opмaн opнaлacтыpу жұмыcтapы өзiнiң дaмуындa ұзaқ жәнe күpдeлi жaғдaйлapдaн өттi. Қaзipгi opмaн opнaлacтыpудың epeкшeлiктepi мeн жeтicтiктepiн түciну және oның құpылуы. Ocының нeгiзiндe opмaн пaйдaлaнудың aғымдaғы мәceлeлepi шeшiлeдi (opмaн қopындa бip жылдa бoлғaн өзгepicтepдi ecкepe oтыpып жәнe opмaн opнaлacтыpу жoбacының ұcыныcтapынa caй), шapуaшылық жұмыcтapдың нәтижeлepi бaғaлaнaды, opмaн pecуpcтapының жaғдaйы туpaлы aқпapaт бepiлeдi Рecпубликaмыздың opмaн шapуaшылық мeкeмeлepiнiң шapуaшылық жұмыcтapының жocпapын өңдeудi Қaзaқcтaндaғы opмaн шapуaшылық мeкeмeлepiнiң aлдындa тұpғaн күpдeлi мәceлeлepдi шeшугe мүмкiншiлiгi өтe жoғapы. Oның нeгiзгi мaқcaты - opмaн шapуaшылығын жүpгiзудe, opмaнды көбeйтудe, күзeту жәнe қopғaудa opмaн pecуpcтapы туpaлы ceнiмдi aқпapaт aлу жoлымeн кeшeндi өңдeлгeн мәлiмeттepмeн  opмaн шapуaшылық мeкeмeлepiн қaмтaмacыз eту. Мeмлeкeттiк opмaн кaдacтpын жәнe opмaн мoнитopингiн құpу, opмaн пaйдaлaнудың нaқты aнықтaлғaн көлeмiн, opмaн көбeйтудiң ic-шapaлapын ic-әpeкeттepмeн жұмыc жacaуын бaқылaу шapaлapын жүзeгe acыpуғa бaғыттaлғaн. Opмaн шapуaшылығын жүpгiзу мeн opмaн pecуpcтapын пaйдaлaну, opмaнды ұдaйы өндipу, күзeту жәнe қopғaу жұмыcтapының тиiмдiлiгiнe, opмaн шapуaшылығындaғы ғылыми-тexникaлық caяcaттың бipыңғaй бoлуынa бaғыттaлғaн шapaлap жүйeciн жacaу opмaн opнaлacтыpудың нeгiзгi мaқcaты бoлып тaбылaды. Қaзipгi уaқыттa мeмлeкeтiмiздiң aлғa қoйғaн мaқcaты opмaн қopын дұpыc пaйдaлaнa oтыpып, opмaн шapуaшылығын тиiмдi ұйымдacтыpу apқылы pecпубликaмыздaғы opмaн қopлapын көбeйту. Opмaн шapуaшылығының нeгiзгi мaқcaты: opмaн қopын көбeйту, xaлықтың aғaш өнiмдepi мeн бacқa opмaн тaуapлapынa дeгeн мұқтaждығын тoлық қaмтaмacыз eту, opмaнды өpттeн күзeту, aуpулapдaн қopғaу, opмaнның қopғaныштық құpылымын жoғapылaту жәнe opмaн бaйлығын көбeйту. Кeйiнгi уaқыттa opмaн шapуaшылығындa жәнe opмaн өндipiciндe көптeгeн ГAЖ тexнoлoгиялap қoлдaныcқa eнгiзiлiп oтыp. Бүгінгі таңда орман шаруашылығының белсенділігін арттыру, орманмен қамтылған жерлерді көбейту көкейтесті мәселе болып отыр. Егеменді еліміздің тірегі, болашағы-жасыл орман. Қазіргі орман шаруашылығының басшыларының алдында тұрған басты міндет- орманшыларды бәсекеге қабілетті, жан- жақты тұлға ретінде жұмыстарын қалыптастыру.
PENINGKATAN PEMAHAMAN SAHABAT LANSIA KOTA BANDUNG MENGENAI KESELAMATAN LANSIA DI RUMAH
Authors: Handayani Solihin Asri
Published: April 2023

Lansia merupakan kelompok yang rentan mengalami masalah kesehatan sehingga perlu diperhatikan oleh keluarga maupun lingkungan sekitar. Salah satu upaya pemberdayaan masyarakat yaitu dengan adanya Sahabat Lansia. Sahabat lansia merupakan salah satu kelompok masyarakat yang peduli terhadap kesehatan lansia dan dapat berfungsi sebagai kader kesehatan lansia. Sebagai kader kesehatan, sahabat lansia perlu dibekali pemahaman terutama mengenai keselamatan lansia karena lansia di rumah perlu dipenuhi kebutuhan keselamatannya. Tujuan pengabdian masyarakat untuk meningkatkan pemahaman sahabat lansia mengenai keselamatan lansia di rumah. Pengabdian masyarakat dilakukan dengan tehnik edukasi terhadap sahabat lansia. Hasil edukasi diperloha bahwa sebagian besar Sahabat Lansia memiliki pengetahuan yang baik mengenai keselamatan lansia di rumah. Disarankan Sahabat Lansia dapat melakukan edukasi kepada keluarga lansia mengenai keselamatan lansia di rumah.
PELATIHAN TEKNIK MEYUSUI DAN PEMBERIAN ASI EKSKLUSIF DALAM UPAYA PENINGKATAN STATUS GIZI BALITA BAGI KADER POSYANDU
Authors: Herawati Yanti
Published: April 2023

Jumlah  kematian  balita  di  dunia  cukup  tinggi,  hampir  10  juta  balita  meninggal  setiap  tahunnya. Beberapa  faktor penyebab kematian  pada  balita  harus ditekan  dengan  pemberian ASI eksklusif pada bayi 0-6 bulan, dimulai dengan inisiasi menyusu dini (IMD). Sampai saat ini cakupan ASI Eksklusif dan   pelaksanaan   IMD   masih   rendah,   padahal   program   NASI   dan   IMD   Eksklusif   telah direkomendasikan  oleh  WHO  dan  UNICEF.  Rendahnya  cakupan  ini disebabkan  oleh  banyak  faktor antara  lain  masalah  dalam  proses  menyusui,  faktor  ekonomi  dan  dukungan  dari  lingkungan  sekitar, sosial  budaya,  perasaan  malu,  pekerjaan  dan  pelayanan  kesehatan  serta  kurangnya  atau  rendahnya tingkat  pengetahuan  masyarakat  tentang  ASI  eksklusif. Menyusui  secara  penuh  atau  eksklusif direkomendasikan   secara   internasional   oleh Organisasi  Kesehatan  Dunia.  Pemberian  ASI eksklusif  berarti  tidak  memberi  bayi  makanan atau  minuman  lain,  termasuk  air;  selain  ASI (obat-obatan  dan  vitamin  dan  mineral  tetes diizinkan).  Teknik pelatihan yang dilaksanakan dilakukan pada kader posyandu di wilayah Puskesmas kahuripan sebanyak 20 orang. Terjadi peningkatan pengetahun setelah diberikan pelatihan
SOSIALISASI TENTANG FAKTOR RISIKO PENYAKIT TIDAK MENULAR (PTM) PADA PELATIHAN KADER PTM
Authors: Suparni Suparni , Mahwati Yeni , Hartiningsih Siti Sugih , Gorta Winara , Ayu Tereza Sarah , Putri Mardani Natsya , Alfiani Novita
Published: April 2023

Penyakit Tidak Menular (PTM) terutama penyakit jantung, kanker, penyakit pernapasan kronis dan diabetes adalah pembunuh terbesar didunia dengan 35 juta kematian setiap tahun dan merupakan penyebab dari sekitar 60% kematian global. Hasil Riskesdas 2018 menunjukkan prevalensi penyakit tidak menular mengalami kenaikan jika dibandingkan dengan Riskesdas 2013, antara lain kanker, stroke, penyakit ginjal kronis, diabetes melitus, dan hipertensi. Prevalensi kanker berdasarkan diagnosis dokter naik dari 1,4 permil (2013) menjadi 1,8 pemil (2018), lebih tinggi pada perempuan (2,9 permil) dibandingkan pada laki-laki (0,7 permil) (Kemenkes RI, 2019b).

Prevalensi hipertensi berdasarkan diagnosis dokter atau minum obat anti hipertensi pada penduduk umur ≥18 Tahun menurut Provinsi, Jawa Barat 9.67% dan 9.97% di atas angka nasional 8.36 % dan 8.84% (Kemenkes RI, 2019b).

Berdasarkan hasil pendatan yang dilakukan pada kegiatan Pengalaman Belajar Lapangan (PBL) di Desa Mekarmanik Kecamatan Cimenyan Kabupaten Bandung, ditemukan permasalahan yaitu cukup tingginya angka kejadian hipertensi. Selain itu jumlah kader terlatih sebagai ujung tombak upaya skrining PTM masih sangat sedikit. Dosen dan mahasiswa Prodi Sarjana Kesehatan Masyarakat melaksanakan kegiatan berupa pelatihan kader PTM untuk mendukung upaya pencegahan dan pengendalian PTM. Pelatihan dilaksanakan pada hari Kamis, 13 Februari 2020. Hasil pelatihan menunjukkan bahwa rata-rata pengetahuan kader mengenai PTM mengalami peningkatan setelah dilakukan pelatihan.Nilai minimum pengetahuan sebelum pelatihan adalah 9 dan nilai maksimum adalah 15 dengan nilai rata-rata sebesar 12,08 dan standar deviasi 2,253. sedangkan nilai minimum pengetahuan setelah dilakukan pelatihan adalah Berdasarkan hasil uji statistik didapatkan p-value = 0,014 < 0,05. dengan demikian dapat disimpulkan adanya perbedaan bermakna rata-rata pengetahuan sebelum dan sesudah pelatihan.

Kader PTM telah dapat melakukan pemeriksaan kesehatan terkait dengan upaya skrining PTM. Kader terlatih ini diharapkan menjadi penggerak posbindu yang belum berjalan secara optimal. Diharapkan seluruh stakeholder (pemerintah desa setempat, Puskesmas, Dinas Kesehatan Kabupaten Bandung dan STIKes Dharma Hsuada Bandung dapat terus memberikan dukungan kebijakan, sarana dan prasarana agar upaya pencegahan dan pengendalian PTM terus dapat dilakukan.
TD 2686 - Contextualização da Política Urbana no Brasil e Reflexões Iniciais Para a Construção da PNDU
Authors: Costa Marco Aurélio , Marguti Bárbara Oliveira , Lubambo Cátia Wanderley , Araújo Junior Edmar Augusto Santos de , Bruno Ana Paula , Krause Cleandro Henrique
Published: April 2023

Este Texto para Discussão tem como objetivo contextualizar o processo de construção da Política Nacional de Desenvolvimento Urbano (PNDU), bem como produzir e sistematizar um material de referência para sua formulação, sua implementação e seu monitoramento. As dimensões temporal e espacial do percurso da política urbana no Brasil, no período pós-Constituição Federal de 1988, revelam a visão de território considerada na formulação da PNDU. As normas, práticas e ações públicas nacionais, regionais e locais recentes permitem entender como os instrumentos da política urbana relacionam-se com a diversidade de escalas territoriais e com as transferências interfederativas para o fi nanciamento urbano. A abordagem sobre o direito à cidade refl ete a aderência da PNDU às agendas internacionais, aos temas transversais (transformações demográfi ca, ambiental e climática; transformação digital; desenvolvimento econômico local; e segurança urbana) e aos marcos nacionais, sobretudo o Estatuto da Cidade, instrumento fundamental para a promoção do justo fi nanciamento da política urbana, por meio da gestão de mais-valias fundiárias.
TD 2694 - Impactos Regionais de Choques de Produtividade e Redução de Desigualdades : O Caso de Região Nordeste
Authors: Oliveira Carlos Wagner de Albuquerque , Cruz Bruno de Oliveira
Published: April 2023

Este Texto para Discussão analisa impactos regionais de diferentes políticas sobre as tendências de médio e longo prazos, em especial para o Nordeste, em um momento pré-pandemia e pré-recessão (2015-2016), utilizando a ferramenta International Futures (IFs). A ferramenta está fundamentada em um conjunto de modelos teóricos que é rodado tomando como base os dados contidos em séries históricas que cobrem mais de 186 países. Os modelos conseguem simular os impactos globais de alterações de políticas e suas inter-relações entre países e blocos econômicos. Os resultados mostram, primeiramente, que a tendência de crescimento do produto interno bruto (PIB) per capita da economia brasileira e da América Latina estava abaixo das demais regiões do mundo, e a economia brasileira tinha uma perspectiva de crescimento ainda menor que a América Latina. Em segundo lugar, choques de produtividade (definidos de maneira ampla) elevam a taxa de crescimento do PIB per capita da economia brasileira. No cenário-base, a taxa média anual de crescimento entre 2015 e 2030 foi de 0,61%, enquanto no cenário com choques de produtividade essa taxa passou para 1,23%. O cenário combinado de aumentos de redução de desigualdades apresenta a maior taxa média anual de crescimento do PIB per capita (1,42%) quando comparado com os outros cenários. O cenário de redução de desigualdades tem pouco impacto sobre essa taxa, mas o impacto é elevado quando se trata da redução de desigualdade e melhoria no de desenvolvimento humano (IDH). Em terceiro lugar, mesmo com choques de produtividade e crescimento acima da média brasileira, nenhum dos estados nordestinos atingiria 75% do PIB per capita nacional em 2030. Mesmo no cenário de maior crescimento, os níveis de desigualdade inter-regional são mantidos, não há alteração nos coeficientes de convergência beta dos PIBs per capita e encontra-se, inclusive, divergência na convergência sigma. Em quarto lugar, nos dois cenários que atacam diretamente as desigualdades, a taxa de extrema pobreza é reduzida de forma mais acentuada, mas ainda assim os estados do Nordeste não conseguem eliminar por completo a pobreza extrema (pessoas que recebem menos de US$ 1,25 por dia) em 2030. Em quinto lugar, e por fim, calcula-se a elasticidade de redução da taxa de pobreza com relação ao PIB per capita e ao Gini nos diferentes cenários. A maior estimativa para a elasticidade do PIB per capita é de -1,35 e para a elasticidade do Gini, 3,05. Conclui-se que, no cenário combinado, o crescimento econômico explica aproximadamente 35% da redução da taxa de pobreza no Nordeste, e a redução de desigualdades, aproximadamente 56%. Em resumo, os resultados mostram que políticas de melhoria da produtividade e redução de desigualdades pessoais sem um foco em áreas mais carentes do país não são suficientes para reduzir o quadro de desigualdades regionais.
Discovery of a 0.64 M
⊙ 13.4 au Companion to the roAp Star HIP 47145 = HR 3831 = IM Vel*
Authors: Waisberg Idel , Klein Ygal , Katz Boaz
Published: April 2023

Our knowledge about the multiplicity of intermediate mass A- and B-type stars is still incomplete, in particular for high (3+) multiplicity systems. Here we report the discovery of a new companion to the nearby roAp star HIP 47145 = HR 3831 with a K band flux ratio of 4% based on a VLTI/GRAVITY interferometric observation. This new 0.64M
⊙ companion at a projected separation 187.5 mas ↔ 13.40 au explains the Hipparcos-GaiaDR2 proper motion change of HR 3831. Together with the previously known M ≈ 1M
⊙ companion at 3″ ↔ 214 au, this makes HR 3831 a hierarchical triple and a very likely progenitor for a system similar to 40 Eridani.
AGN Sub-populations Important for Black Hole Mass Growth: A Rule of Thumb
Authors: Buchner Johannes
Published: April 2023

For building the super-massive black hole population within a Hubble time, only sub-populations with more than

10

52

erg

s

−
1

/

L

¯

objects on the sky are relevant, where

L

¯

is the sample-averaged bolometric luminosity.
Être propriétaire à l’heure de la retraite : capitaliser et assurer son avenir
Authors: Chamahian Aline , Petite Ségolène
Published: April 2023

L’objet de cet article est de comprendre le sens que les personnes retraitées ou proches de la retraite, qui font partie de la génération qui a largement pu accéder à la propriété, donnent au fait d’être propriétaire. En interrogeant les enjeux qui se dessinent autour de la propriété et les incidences du statut de propriétaire sur la trajectoire résidentielle future, nous explorerons comment le logement s’inscrit dans un processus de capitalisation. Notre propos sera construit en deux temps. D’abord, nous décrirons les trajectoires d’accession à la propriété, leurs déclencheurs et l’attachement voué à ce statut, ce qui permettra de montrer les enjeux autour de l’entretien du capital résidentiel. Ensuite, notre regard se portera sur le temps de la retraite comme moment charnière de construction de stratégies résidentielles, entre rester et partir. Ces stratégies reconfigurent les formes de ce capital et sont prises en tension entre l’enjeu du financement de sa future dépendance et la constitution d’un capital transmissible. L’article se fonde sur un corpus de 30 entretiens réalisés entre mars 2015 et mai 2016, en Île-de-France, dans le Nord et le Pas-de-Calais, auprès de propriétaires ou d’accédants à la propriété âgés de 52 à 73 ans (post-enquête qualitative à l’enquête Logement de 2013).