bluuebunny/crossref_metadata_2025 huggingface dataset:
Challenges and Coping Mechanisms in Supervision of the Instructional Leaders in the New Normal
Authors:   https://orcid.org/0000-0003-3892-819X gcmagno@bpsu.edu.ph Bataan Peninsula State University, Bataan, Philippines, C. Magno Glenda
Published: June 2023

Supervision is an important role of instructional leaders in the new normal and is a pressing global issue. The study found out what challenges and coping mechanisms instructional leaders faced in supervising in the new normal. This is a pressing global issue that is of great interest to stakeholders. This mixed research method involved 102 faculty respondents and 6 Deans of the different Bataan Peninsula State University colleges. Results showed that 26 or 25.49% of the respondents belong to the age group of 32 to 39 years old. The Deans were designated as early as 3 months to 12 years. Their supervision experiences with the teachers and students include difficulties in monitoring teachers and students and innovative methods of instruction. Data showed that the deans considered planning a program for curriculum development (Mean=3.54, SD=0.82) as very challenging. Data indicate that a significant difference is not evident in the perception of teacher-respondents on the challenges their deans met in the new normal and the deans’ coping mechanisms in resolving the challenges they met in the new normal when grouped according to the length of service. The analysis using Spearman’s rho indicates a very weak positive correlation between coping mechanisms and the challenges in planning a program for curriculum development, implementing a definite program of supervision, and providing leadership in the professional upgrading of the faculty. The p-values which are statistically lesser than the alpha of .05 indicate that there is not enough evidence to claim that the relationship is significant, thus, it fails to reject the null hypothesis. The challenges that were experienced in supervision included the Dearth of Resources, Communication, and Age barriers. Coping mechanisms that they employed include versatility and flexibility in leadership. Supervisory competencies of instructional lead include Interpersonal Skills. Keywords: Challenges and Coping Mechanisms, Convergent Mixed Method, Instructional Leaders, New Normal, Philippines
BULLYING NO AMBIENTE ESCOLAR E O SUICÍDIO DE CRIANÇAS E ADOLESCENTES
Authors: Borges de Amorim Sérgio
Published: June 2023

Objetivou-se, com este artigo, realizar uma reflexão acerca da necessidade de se promover pesquisas com caráter científico acerca da temática do bullying no ambiente escolar e de como esse fenômeno afeta crianças e adolescentes ao ponto de conduzi-los ao suicídio. Nesse sentido, realizou-se uma breve revisão bibliográfica, dada a característica sumária deste tipo de publicação, na qual se discutiu a origem do termo bullying, sua relação com a violência nas escolas, e as principiais características desta prática que já está foi tipificada na legislação brasileira, conforme Lei Federal nº. 13.185/2015. Em um segundo momento, realizou-se uma pesquisa no Catálogo de Teses e Dissertações da CAPES para identificar o quantitativo de produções acadêmico-científicas existentes, no período escolhido, relativas ao tema bullying e sua relação direta com o suicídio de escolares, com base nos critérios de pesquisa previamente estabelecidos e justificados pelo pesquisador ao longo do desenvolvimento teórico. Concluiu-se que a produção foi insipiente no período pesquisado, e que se faz necessário promover reflexões, estudos, debates e pesquisas para embasar uma implantação contínua de políticas públicas para prevenção, mitigação e punição do bullying nas escolas.
Wahyu Hidayat's Terrorism Financing Deradicalization Strategy
Authors: Anisa Ika Veni , Syauqillah Muhamad
Published: June 2023

The deradicalization programme is mandated by Law No. 5/2018, especially in approaching prisoners of terrorism. The deradicalization programme is carried out so that prisoners abandon their acts of violence and crime and even abandon radical thoughts or ideologies. This programme is implemented both inside and outside the prison. This research reveals the deradicalization program experienced by terrorism convict Wahyu Hidayat. This research is qualitative research with a case study research type. The primary data in this research are interviews with Wahyu Hidayat, Densus 88 Anti-Terror Polri investigators and BNPT deradicalization personnel. The results of this research show that, currently, the disengagement program for Wahyu Hidayat has succeeded in making him leave his group, Wahyu Hidayat is still in prison in the stage of developing his identity and social reintegration with various programs. Based on this, the rapid change in Wahyu Hidayat's attitude needs to be a precaution for BNPT in conducting identification as an initial stage of deradicalization, as well as the need for a sustainable program to ensure Wahyu Hidayat does not re-offend.
Financial Performance Analysis of Airlines Operating in Europe: CRITIC Based MAUT and MARCOS Methods
Authors: SUMERLİ SARIGÜL Sevgi , ÜNLÜ Merve , YAŞAR Esra
Published: June 2023

This paper aims to measure the financial performance of 6 airline operators operating in Europe between the periods of 2019-2021. For performance measurement, 8 financial criteria were used: current ratio, cash ratio, financial leverage ratio, equity multiplier, asset turnover rate, equity turnover rate, return on equity and return on assets ratio. For the analysis of these criteria, the importance levels of the criteria related to the CRITIC method, one of the MCDM methods, were determined. At the same time, with the MAUT and MARCOS methods, the financial performance ranking of the airline enterprises was obtained according to the relevant years. According to the findings of the CRITIC method; It was determined that asset turnover rate in 2019 and financial leverage ratio criteria in 2020 and 2019 were the most important criteria. As a result of the MAUT method, it was concluded that the airline with the best financial performance in 2019, 2020 and 2021 was Air France. According to the findings of the MARCOS method, the airline with the highest financial performance in 2019 was Pegasus Airlines and in 2020 and 2021 it was determined as EasyJet.
Türk Anıtlarında Bağlamın Biçim ile Kuruluşu
Authors: KOLBAY Sevda Duygu
Published: June 2023

Biçim, uygarlık tarihinin her döneminde, nesnenin maddesel içeriğini üretmenin ötesinde, toplumlara ait varoluş değerlerinin aktarımı için yegâne araç olmuştur. Tarihin devingen işleyiş sürecinde her bir yeni sosyal-kültürel, toplumsal, ideolojik ve teknolojik gelişme önceki dönemlere ait biçim olasılıklarını tamamlar ve/veya değiştirir. Anadolu coğrafyasında, toplumsallığın yapısal tezahürleri Türk ulusal kimliğinin baskın izlerini taşımaktadır. Bu çalışmada, nesnenin yapısallığının özündeki imgesel referanslarla bütünleştirildiğinde okunaklı olabileceği argümanı üzerinden, Türk anıtlarında biçim ile tanımlanmış olan bağlamsal karşılığı araştırmak hedeflenmektedir. Bu amaçla, yazınsal ve görsel kaynaklardan toplanan verilerin tümel düzen içinde yorumlanıp, ortaya çıkan örüntüler üzerinden çeşitliliğinin irdelenmesine dayalı nitel bir çalışma yöntemi izlenmiştir. İçerik, Selçuklu, Osmanlı ve Türkiye Cumhuriyeti Dönemi anıtlarının meydana getirdiği çeşitlilik özelinde ele alınmıştır. Çalışmada, dizge aktarımı kronolojik olarak gelişim gösterse de Anadolu-Türk kimliğini yansıtan biçim özelliklerinin belirginleştiği veya kırılmalara uğradığı inşa edimleri, yanıtların arayışında geniş bir söz alanı oluşturmaktadır. Anlamı taşıyan ifade değerinin tasarlanarak veya zamanla çağrışımsal olarak ortaya çıkışındaki ontolojik çeşitlilik, Türk mimari eserleri ve Türk sanat yapıtları başlıkları altında toplanmıştır. Türk mimarisinde, yapısal öğelerin düzeni ve çeşitliliği ile inşa edimi biçimin kökenlerine dair referanslar içermektedir. Türk sanatında ise, anlam aktarımının biçimsel araçları, bezeme ve bağımsız plastik öğeler ile farklı anlamsal karşılıkları yakalamaktadır. Bu başlıklardan elde edilen çıkarımlar doğrultusunda ortaya çıkan kuram ve bulgular, biçim ile taşınan koşut değerlere dayalı örtük bilgi üzerinden kuramın dönüşümünde etkili önemli tartışma alanlarını görünür kılmaktadır.
La Política Pública Alimentaria Latinoamericana en el marco de la Agenda 2030
Authors: Zapata Carnaqué Esperanza Marlene , Caicedo Pareja María José , Caballero Gómez Sandra Paola , Sevillano Quiñones Dina Gissel
Published: June 2023

La Política Pública Alimentaria Latinoamericana es de gran relevancia en la región, especialmente en el marco de la Agenda 2030 para el Desarrollo Sostenible. Su objetivo es analizar la implementación y el impacto de la Política Pública Alimentaria Latinoamericana en el marco de la Agenda 2030 evaluando su efectividad en la mejora de la seguridad alimentaria y nutricional en la región. Se recopilaron datos de diversas fuentes como informes internacionales y políticas gubernamentales realizándose un análisis comparativo de programas en diferentes países. Se consideraron aspectos como producción agrícola, distribución de alimentos, educación alimentaria y participación de los actores involucrados. Los resultados mostraron avances significativos. Hubo una mayor disponibilidad y acceso a alimentos nutritivos, así como la implementación de programas de educación efectivos. Además, se observó una disminución en los índices de desnutrición y malnutrición en algunos países. Sin embargo, persisten desafíos, como la desigualdad en el acceso a alimentos y los impactos del cambio climático en la producción agrícola. Es necesario fortalecer la colaboración entre los actores involucrados y seguir implementando políticas y programas efectivos. En conclusión, la Política Pública Alimentaria Latinoamericana en el marco de la Agenda 2030 ha tenido un impacto positivo en la mejora de la seguridad alimentaria y nutricional en la región. Para alcanzar los objetivos establecidos en la Agenda 2030, es fundamental abordar los desafíos pendientes y fortalecer la colaboración entre los diferentes actores. Esto garantizará una alimentación adecuada para todos los latinoamericanos y promoverá un futuro sostenible en términos de alimentación y nutrición.
Perceptions About Motivation Towards Teaching English Language Employing Madrasati Platform During the Pandemic
Authors: Mahmud Fawaz Al , Saqlain Nadeem
Published: June 2023

This study investigates motivation towards teaching English language using Madrasati platform. The research methodology was mixed methods research for this study. The review of the most recent studies on the topic were included. The quantitative data were collected through surveys during Spring 2022, and an instrument was administered to obtain data. In this study, 382 (236 male and 146 female) in-services English language teachers were selected at random as participants. The samples were the representation of both genders. They were also representatives of all teachers’ qualifications including diploma to PhD degrees. For the qualitative part of the study, ten participants were purposefully selected to obtain data. The source of qualitative data collection were interviews. The results of this mixed methods study displayed that the participants had positive perceptions in general of using Madrasati platform. Some motivational factors were found in this study e.g., flexibility, teaching with technology, using Madrasati. The participants found better attendance in their online courses. However, the participants indicated some challenges such as training to use technology, connectivity, and distraction.
Consumer Preferences and Attitudes in Debt Collection: A Cross-Generational Investigation
Authors: Goetze Minou , Herdt Christina , Conrad Ricarda , Stricker Stephan
Published: June 2023

Preliminary research indicated that an increasing number of young adults end up in debt collection. Yet, debt collection agencies (DCAs) are still lacking knowledge on how to approach these consumers. A large-scale mixed-methods survey of consumers in Germany (N = 996) was conducted to investigate preference shifts from traditional to digital payment, and communication channels; and attitude shifts towards financial institutions. Our results show that, indeed, younger consumers are more likely to prefer digital payment methods (e.g., Paypal, Apple Pay), while older consumers are more likely to prefer traditional payment methods such as manual transfer. In the case of communication channels, we found that older consumers were more likely to prefer letters than younger consumers. Additional factors that had an influence on payment and communication preferences include gender, income and living in an urban area. Finally, we observed attitude shifts of younger consumers by exhibiting more openness when talking about their debt than older consumers. In summary, our findings show that consumers’ preferences are influenced by individual differences, specifically age, and we discuss how DCAs can leverage these insights to optimize their processes.
Status of Migratory Beekeeping With Apis Mellifera L In the Gangetic Plain of West Bengal
Authors: Das Rakesh , Layek Amit , Kunal Gautam , Jha Shantanu
Published: June 2023

Honey bees are humanity’s unique gift. In addition to various hive products, human are benefited with the most valuable ecosystem service, i.e. pollination by honey bees. The study has been attempted to explore the overview of migratory beekeeping with Apis mellifera L. in the potential Gangetic delta of West Bengal, India through questionnaire survey. Honey flow season lasts from mid/ end of October to mid/end of May, whereas June, July, August and September are beekeeping dearth in this region. Beekeepers used to move their colonies successively between intra- and inter-district locations to harvest honey from trees like eucalyptus, mustard, coriander, black cumin, litchi, sesame, and/or mangroves. Marketing of honey and middleman issue are the major limitations identified. This study presents an illustrative overview of beekeeping status in this area, its potential as well as limitations, and proper initiative to proliferate the enterprise at its outmost.
Efficacy of Beauveria Bassiana and Metarhizium anisopliae Against Tomato Leaf Miner Phthorimaea Absoluta(meyrick)
Authors: T K Dabsu , O B Kovanci
Published: June 2023

The tomato leaf miner Phthorimaea absoluta(Meyrick), earlier known by the scientific name Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is one of the most devastating global pests of tomatoes. Using indigenous entomopathogenic fungi can be a promising solution to manage it. Effıcacyof EPF isolates on third-instar larvae was carried out in Ethiopia during 2021-2022. Ten larvae were inoculated with conidiaa suspensions with three replications. The result showed that larval mortality was significantly different (p<0.05) among concentrations and isolates. Beauveria bassiana isolates caused 70 to 81% mortality, the lowest LC 50 was 1.87x104 to 9.79x10 4 conidia/ ml; and LC 95 was 5.68x108 to 1.10x10 11 conidia/ml and shortest LT 50 was 3.6 to 5.7 days. These were considered highly virulent while Metarhizium anisopliae determined as moderately virulent having 46 to 63% mortality (highest LC50 was 1.36x106 to 4.94x10 7and LT 50 was 4.3 to 8 days). Results also revealed 1x10 10 conidia/ ml is the most effective dose while 1x10 6 is the least effective.
Altitudinal Variations in the Mound Nests of Termites Odontotermes Wallonensis and O. obesus
Authors: Brahma Nirmali , Haloi Akshay Kumar
Published: June 2023

The nesting form of the mound nest of species Odontotermes wallonensis(E. Wasmann) and Odontotermes obesus (Rambur) was studied in hilly and tropical deciduous forest area of Kakoijana Reserved Forest of Abhayapuri (Bongaigaon district). It was compared to the plain village forest area of Baksa district (Bajegaon Pather). The morphometric measurement such as height, circumference, depth of the mound nest and the royal chamber from the surface of the ground was recorded along with weight of fungus garden and queen and their sections were photographed. The outcomes revealed that the location of the nest influences the structure and characteristics of the nest. The young and established mound nests of species O. obesus and O. wallonensis in hilly and plain area had different shape, sizes and colour. The shade of the fungus garden was buff i.e., yellowish brown in young nest whereas it was blackish brown in established nests. The queen termite and the royal chamber unable to be excavated were in hilly area as compared to the plain area. In some of the mound nests, no traces of the queen termites and rest of the castes were observed; and the mound was dead i.e., abandoned after the death of queen termite.
Effect of Insecticides Evaluated Against Earias spp. on the Population of Amrasca biguttula Biguttula and Bemisia Tabaciin Okra
Authors: Singh Bhupender , Karan Gaur Ram , Jakhar Anil
Published: June 2023

Present study was conducted at the CCS Haryana Agricultural University, Hisar during kharif 2019 and 2020. Insecticides viz., chlorantraniliprole 18.5 SC, emamectin benzoate 5SG, lambda-cyhalothrin 5EC, pyridalyl 10EC, cypermethrin 25EC and quinalphos 25EC were applied thrice at recommended dose of 25, 6.75, 15, 50, 37 and 200 g a.i. ha -1 , respectively for the management of Earias spp. in okra. The effect of these on the incidence of Amrasca biguttula biguttula (Ishida) and Bemisia tabaci (Genn.) was also assessed. Results revealed that application of quinalphos caused maximum reduction (54%) of A. biguttula biguttula followed by chlorantraniliprole (43.40%) and lambdacyhalothrin (42.80%). In case of B. tabaci, application of chlorantraniliprole caused maximum reduction (44.74%) followed by lambdacyhalothrin (33.33%) and emamectin benzoate (28.16%).
Effects of Population Density on Survival, Development Time, Fecundity and Hatchability of Samia cynthia ricini Boisduval
Authors: Nurkomar Ihsan , Trisnawati Dina Wahyu , Wening Firda Kartika
Published: June 2023

Samia cynthia ricini Boisduval Lepidoptera:Saturniidae is a lepidopteran insect that has a gregarious behaviour during their larval stage. This research aimed to determine the minimum population limit of larvae that can support the survival of S. c. ricini by observing the development time, fecundity, and hatchability of eggs produced by adult moths under different larval densities rearing conditions. The research was conducted by observing the lifecycle and development of S. c. ricini at different population densities. The results showed that density had effect on the development time of S. c. ricini egg only. Population density also affects the survival and adult fecundity of S. c. ricini. A density of 30 is the minimum population required to support the success of S. c. ricini’slife. Samia cynthia ricini reared at this density had the highest survival rate, faster egg development time, heavier cocoon shell weight and highest fecundity.
Juvenile Hormone-Induced Abnormality of Periplaneta americana (L.)
Authors: Borah Nirmali , Hazarika Lakshmi Kanta
Published: June 2023

Application of juvenile hormone III (JH III) and a JH analogue, methoprene to last instars of Periplaneta americana suppressed adult emergence and caused morphological abnormalities such as twisted wings and asymmetry of appendages resulting in formation of either nymphoids or giant supernumerary nymphs and adultoids. The effects of JH III and methoprene were concentration dependent in inducing aberrations in morphogenetic moult as well as in significantly lowering the body mass (BM) and lipid reserves (LR) in P. americana.
Effects of Ants on the Fruit Setting of Artabotrys Odoratissimus R. Br.
Authors: A Saravana Ganthi , K Vellankanni , T Suresh Kumar
Published: June 2023

Floral volatile compounds exhibit multiple functions such as attracting pollinators, source of food for pollinator and act as defense against herbivore. Thus floral scents may function as allomones to prevent enemies as well as being synomones to attract pollinating mutualist. Flowers are morphological and embryological marvels and the sites of sexual reproduction. The yellow coloured flowers of Artabotrys odoratissimus R. Br. are very fragrant. The floral volatile of this plant attracts weaver ants. It plays a crucial role in plant- ant interaction. The present study aims to explore the effect of ants on the reproductive success of A. odoratissimus. Ants are detrimental to A. odoratissimus and disturb the pollinator visits which resulted in reduced fruit set. The nest constructed leaves experience premature death, thus weaver ants show antagonistic effect in the selected species.
TÜRK CEZA HUKUKUNDA İRTİKÂP SUÇU
Authors: NEMLİ Mekin
Published: June 2023

İrtikâp suçu 5237 sayılı Türk Ceza Kanunu’nun 250’nci maddesinde düzenlenmiştir. İrtikâp suçunun; icbar suretiyle, ikna suretiyle ve hatadan yararlanmak suretiyle olmak üzere üç işleniş şekli bulunmaktadır. İrtikâp suçu özgü suç olup, suçun faili sadece kamu görevlisi olabileceğinden kamu görevlisi olmayanlar “müstakil fail” veya “müşterek fail” olamazlar. Bu suçların işlenişine iştirak eden kamu görevlisi dışındaki kişiler “azmettiren” veya ‘yardım eden’ olarak sorumlu tutulurlar. Maddenin ilk şeklinde, icbar suretiyle irtikâp suçunun unsurlarından olan “icbar” kavramının tanımı yapılmamıştı. 6352 sayılı Kanunla “icbar” kavramının tanımı yapılarak, TCK’nın 250’nci maddesinin birinci fıkrasına ikinci cümle olarak eklenmiştir. Kanun metnine “icbarın” tanımının eklenmesiyle, uygulamacıların, icbar suretiyle irtikâp suçunu, rüşvet suçu olarak değerlendirme hatasına düşmelerinin önüne geçilmiştir.6352 sayılı Kanunla icbar kavramının tanımının eklenmesi rüşvet suçuyla icbar suretiyle irtikâp suçunu birbirinden ayırt edilebilmesini kolaylaştırmıştır. Ancak aynı hususu ifade etmek üzere mevcut maddede hangi terim kullanılmışsa kanun değişikliği ile eklenecek fıkralarda da aynı terimin kullanılması beklenir. Oysaki 6352 sayılı kanunla yapılan değişiklikle eklenen fıkralar düzenlenirken aynı terimi kullanmaya özen gösterilmeden düzenlenmiştir.
Effects of Climate Change on Apple Farming in Kashmir Valley
Authors: Sheikh Dr. Bilal Ahmad , Baba Dr. S.H.
Published: June 2023

The effects of climate change on apple farming in the Kashmir valley are becoming increasingly significant. The region's erratic weather patterns, including unpredictable temperature fluctuations, changes in precipitation, and extreme weather events, have a profound impact on apple cultivation. Rising temperatures contribute to increased pest and disease incidence, affecting the health and productivity of apple orchards. Changes in flowering time disrupt pollination and fruit development, leading to potential yield losses. Additionally, water availability and irrigation challenges pose significant risks to apple farming, as reduced snowfall and changing precipitation patterns affect water supply and irrigation practices. The vulnerability of apple orchards to extreme events, such as heavy rains, hailstorms, and unseasonal snowfall, results in physical damage and disrupts transportation and market access. The suitability of certain cultivation areas may shift due to climate change, requiring farmers to adapt their practices and explore new varieties or crop diversification. Mitigation and adaptation strategies, such as climate-resilient farming practices and supportive policies, are necessary to safeguard the sustainability and productivity of apple farming in the Kashmir valley in the face of climate change.
Effects of Handwashing and Antimicrobials on Bacterial Counts
Authors: Hissom Emily
Published: June 2023

It is everyday practice to utilize aseptic techniques, which are simply actions taken to prevent the accumulation of bacteria and other microbes to prevent diseases and their spread. Handwashing is an important aspect of hand hygiene because hands pick up the microbes from surfaces and are easily transported from person to person through direct contact or indirect contact. According to the CDC and WHO, many diseases are spread by not washing hands effectively, therefore hand hygiene is important everywhere in society, especially in healthcare where the spread of disease can mean life or death. In this study, we analyzed data collected from the student population of microbiology classesfrom the University of Charleston in West Virginia over the span of nine years (2014 to present). We measured the number of colony forming units (CFU) from students’ hands prior to manipulation (control), using just water, using soap and water, and using hand sanitizer. We hypothesized that handwashing and use of antimicrobial aids such as hand sanitizer will reduce the number of bacteria on hands compared to controls. An analysis was also performed comparing pre-pandemic and post-pandemic data to determine if handwashing behaviors have changed behavior which would alter the normal microfauna on the hands. This analysis revealed that there was a significant difference between handwashing techniques (p<0.001). There was a difference in formation of colony forming units between pre and post pandemic times (p<0.001).
Identification by DNA barcode of culturable, airborne, environmental fungi isolated from the Shepherd University campus
Authors: Kellison Jessica , Rea Elizabeth , Robertson Laura
Published: June 2023

Diverse fungi are abundant within soil communities and commonly found in association with many plant and tree species.  This study investigates the culturable, airborne fungi found in the outside environment of the Shepherd University campus.  Viable fungi were captured in two different locations on two different culture media, using the open plate method.  Captured fungi were isolated and putative species identified by sequencing the internal transcribed spacer region (ITS) of the ribosomal RNA (rRNA) gene cassette.  Due to insufficient sequence variability within the ITS region, most isolates could not be identified to species.  15 fungal isolates were identified to order, family, genus, or species complex: Dothideales (1 isolate), Didymellaceae (4 isolates), Aureobasidium (1 isolate), Cladosporium (1 isolate), Mucor (3 isolates), Nigrospora (1 isolate), Pestalotiopsis (2 isolates), and Penicillium (2 isolates), including Penicillium thiersii (1 isolate).  These isolates are similar to those isolated from inside a teaching laboratory on the Shepherd University campus; Didymellaceae, Cladosporiaceae, and Penicillium fungi were isolated multiple times within the teaching laboratory.  This research was supported by the Shepherd University Biology Department, a student fellowship from NASA-WVSGC (J. Kellison), and a research enhancement award from NASA-WVSGC (L. Robertson).
Study of Steric Hindrance of Ketone Ester Reduction Chemistry
Authors: Mazhar Sana
Published: June 2023

Drug Discovery Research (DDR) is a process by which new potential therapeutic entities are recognized. Lead discovery and Computer aided drug discovery are two most popular methods in DDR. However, chemical modification such as development of the chemical linker gains its popularity in various therapeutic classes. In this poster, we are proposing four chemical steps starting from commercially available amino acids and their chemical routes for synthesizing linkers. We hypothesize that the more sterically hindered R group on Amino Acid will result in an increase in diastereomer ratio (DR) in reduction chemistry. In this poster we will discuss the detailed chemical reaction methods, their data, and how it’s being proposed as a potential anti-cancer agent.
The identification of bacteria from human microbiota that inhibit the growth of Methicillin-Resistant Staphylococcus aureus
Authors: Gray Reagan
Published: June 2023

Methicillin-Resistant Staphylococcus aureus (MRSA) is an antibiotic-resistant bacterium and a major cause of preventable illness and death. To combat MRSA and other antibiotic-resistant pathogens, alternatives to small molecule therapeutics targeting essential biological pathways of bacteria must be identified. Staphylococci, including MRSA strains, can exist as part of the human microbiota, competing for resources and space with other microorganisms. Here, we sought to identify bacteria from the human microbiota capable of killing or inhibiting the growth of MRSA.  Swabs of the nostrils and skin of two individuals were collected, one being a natural MRSA carrier, and bacteria were isolated from these samples. Of these isolates, eight showed to inhibit the growth of a MRSA strain when cross streaking.  To identify these bacteria, a portion of the 16s rRNA gene of these bacteria was sequenced and compared to known bacteria in the genbank database using BLAST.  Of the eight isolates, three distinct bacterial species were identified: Acinetobacter baumannii, Bacillus aerius, and Staphylococcus epidermidis. Following the identification of these bacteria, we sought to determine the mechanism of inhibition. Cell lysates and extracellular material of these inhibitory bacteria were used in a disk diffusion assay which showed no observable zones of inhibition toward MRSA.  This suggests that these bacteria may need to be viable and/or directly contact MRSA to mediate the inhibition of growth.  To test this hypothesis, phase-contrast microscopy of co-cultured bacteria was used.  While results here suggested that B. aerius directly interfered with the ability of MRSA to replicate, future studies using time-lapse microscopy of fluorescent strains of these microbes should produce data that can be more clearly interpreted.
The analyzation of DNA and cross contamination inside the cyanoacrylate (superglue) fuming chamber.
Authors: Banyi Casie
Published: June 2023

The objectives of this experiment looked at were that the DNA, both skin cells and saliva, have the potential of binding with the superglue as it coats each object being fumed. If DNA has the potential of binding with the superglue, then it is very possible for DNA to be carried in the air by the humidifier, thus contaminating other objects. For the first experiment, two saliva covered microscope slides, one female and one male, were fumed along with 25 other sterile slides. Each sterile slide was swabbed and analyzed for DNA in an electrophoresis gel chamber. The second experiment fumed ten microscope slides presented with fingerprints. Each sterile slide was swabbed and analyzed for DNA in an electrophoresis gel chamber. The results showed that there was minimal cross contamination present on the slides fumed with the saliva based slides. The touch DNA experiment showed that there are potentially identifiable DNA markers present in fingerprints after fuming. The results concluded that it is possible to have DNA cross contamination between items that carry no DNA prior to the fumigation, and potential DNA can be found on fingerprints after fumigation.
Roles of dendritic cells and macrophages during Chlamydia muridarum genital infection in stressed mice
Authors: Baker Danielle
Published: June 2023

It is well known that stress has a significant impact on public health and more evidence shows that stressors generally are greater in populations of lower socioeconomic status. Cold-induced stress inhibits immune cell activity and has been shown to cause different expressions of cytokine profiles during Chlamydia muridarum genital infection. Dendritic cells (DCs) and macrophages(MØ) are immune cells that express beta2-adrenergic receptor (β2-AR) and with key roles during chlamydia genital infection. This study is aimed to investigate the role of β2-AR by using a β2-AR knockout mouse. Wildtype (WT) and β2-AR knockout(KO) mice were stressed for five minutes daily and infected with C. muridarum intravaginally. Non-stressed infected mice of the groups were used as controls. Bone-marrow-derived DCs and MØ were tested isolated, counted differentiated, and proliferated for cytokine production. The proliferation of DCs and macrophages in the presence/absence of β2-AR agonists and antagonists was tested. Data show that non-stressed mice had a higher production of cytokines than stressed mice. Increased production of TNF-α in LPS-treated DCs and MØ of WT and β2-AR KO was observed. The effect of fenoterol and ICI118,55 antagonist showed no significant difference in cytokine production. The data indicate that β2-AR KO and WT had a similar pattern of cytokine production suggesting that deficiency in β2-AR restores the function of immune cells during genital infection. Experiments are undergoing to fully understand the mechanisms involved in modulating the function of DC and MØ during chlamydia genital infection.
Role of KatG in Francisella tularensis Susceptibility to Resazurin.
Authors: Schreiber Rori
Published: June 2023

The CDC classifies Francisella tularensis as a Category A bioterrorism agent. Due to the risk of potential release of antibiotic-resistant F. tularensis strains, new therapeutics against F. tularensis must be developed.  Resazomycins are resazurin (Rz)-based compounds that exhibit antimicrobial activity against F. tularensis and other gram-negative bacteria. The mode of action of resazomycins is not understood, but potential targets of the antibiotic were identified in a high throughput screen for Rz-resistant isolates. The FTL_1504 gene was identified as being mutated in all of the Rz-resistant (Rzr) strains sequenced.  FTL_1504 encodes for the catalase KatG which catalyzes the decomposition of hydrogen peroxide to water and oxygen.  Moreover, KatG has also been shown to play an essential role in the activity of a different antibiotic, isonazid. Four different coding mutations were characterized in katG that included single base pair substitutions and a deletion with all resulting in the introduction of a premature stop codon. All Rzr mutants tested had reduced catalase activity compared to wild-type F. tularensis LVS with three of the four mutations resulting in loss of KatG expression.   Based on this data, we hypothesize KatG plays a role in the susceptibility of F. tularensis to resazurin. To address this, we are generating a katG deletion mutant in F. tularensis LVS and measuring its Rz susceptibility via agar dilution assays. Investigation of the contribution of KatG may unveil a unique role for the oxidative stress response in the mode of action of this family of antibiotics
Basic Cryptographic Concepts and Open Problems in Hash Function Security
Authors: Smith Johnna , Mills Donald
Published: June 2023

JOHNNA SMITH, Dept of Mathematics, Shepherd University, Shepherdstown, WV, 25443, and DONALD MILLS, Dept of Computer Sciences, Mathematics, and Engineering, Shepherd University, Shepherdstown, WV, 25443. Analysis of basic cryptographic concepts and recent open problems in hash function security. 

 

The objectives of this study are to show an understanding of cryptographic concepts as well as highlight recent open problems involving hash function security. The method of study used included reading the first five chapters of Cryptography: Theory and Practice by Stinson and Paterson as well as a recent paper that outlined open problems in hash function security. Then, written reports were delivered on the information learned which included selected proofs and solved examples. The essentials of the opening report introduce the basic elements of cryptography: cryptosystems, cryptographic tools, message integrity, protocols, and security approaches. Chapter 2 of “Cryptography” describes various types of ciphers including Shift, Substitution, Affine, Vigenère, Hill, Permutation, and Stream Ciphers, as well as how to cryptanalyze them. The third report focuses on the One-time Pad, entropy, perfect security, and cryptographic security, specifically unconditional security, as introduced by Claude Shannon in his work on information theory. Throughout the fourth report, block and stream ciphers, including substitution-permutation networks, attacks such as linear and differential cryptanalysis, and modes of operation are discussed. In the fifth report, basic concepts of cryptography, hash function and message authentication are discussed, including iterated hash function, sponge construction, and unconditionally secure MACS. Using the information learned from the previous reports, current problems in hash functions were then researched. In conclusion, open problems in hash function security include collision resistance, preimage resistance, and resistant to length extension attacks. The project was sponsored by the NSF S-STEM Grant (DUE-2130267).
Thelper1 and T helper2 cytokine production patterns in stressed beta2-adrenergic receptor-deficient mice during chlamydia genital infection.
Authors: Rolen Kristen
Published: June 2023

Murine CD4+ T cells have two distinct cytokine secretion patterns to play different functions. We have demonstrated that cold-induced stress (CIS) suppresses the immune system leading to increased intensity of Chlamydia muridaum in mice. We have reported that beta2-adrenergic receptor (b2-AR) knockout (KO) mice resist chlamydia genital infection. However, the cytokine profile of  CD4+ T cells is not well explored. This study aimed to determine the cytokine production of Th1 and Th2 types in stressed and non-stressed b2-AR KO mice. We investigated the cytokine production levels of stressed and non-stressed mice during C. muridarum genital infection. Significantly increased production of cytokines was observed in plates pre-coated with anti-CD3/CD28 or in the presence of  Con A or LPS. A decrease in the production of IFN-g and IL-2, whereas an increase in the secretion of IL-10, IL-13, and IL-23 in CD4+ T cells of stressed wild-type mice was obtained; however, the secretion of IFN-g and IL-2 was restored in T cells of b2-AR KO mice. Moreover, in vitro proliferation of CD4 T cells in the presence of b2-AR antagonists, ICI 118, 551 stimulated the production of Th1 cytokines, whereas b2-AR agonist, Fenoterol, decreased the production of Th1-type cytokines. Overall, Th1 cytokine responses are reduced in stressed mice suggesting that the cytokine status was polarized toward a Th2 immune response that can be restored by removing b2-AR from immune cells.
PENERAPAN MODEL PEMBELAJARAN AKTIF TIPE INDEX CARD MATCH UNTUK MENINGKATKAN HASIL BELAJAR MATEMATIKA PADA SISWA KELAS IV SDN SUMPUT
Authors: Wibowo Anggi Agnes , Islami Selvi Cahya , Amaluddin Muhammad Iqbal
Published: June 2023

Behind this research is the low learning outcomes of students on the material area and perimeter of squares and rectangles in mathematics. The percentage of students' completeness is only 13%. This happened because of the lack of enthusiasm of students in participating in learning in class and there were still many students who did not listen when the teacher explained the material. In addition, learning also uses more lecture methods which result in students being passive in learning. In response to this, it is necessary to apply an index card match strategy to improve mathematics learning outcomes for the area and perimeter of square and rectangular shapes for fourth grade students at SDN Sumput Sidoarjo. The subjects of this study were fourth grade students of SDN Sumput which consisted of 23 students. The results of the study concluded that: Learning by applying the Index Card Match strategy can improve student learning outcomes. This is evidenced by an increase in student learning outcomes in learning activities in each cycle. In the first cycle, the percentage of success criteria was 13.1%. While in the second cycle the percentage of student success increased to 82.7%. This proves that the index card match (ICM) learning model can improve the learning outcomes of fourth grade elementary school students in the area and perimeter of flat shapes
MENINGKATKAN HASIL BELAJAR SENI BUDAYA DAN KETERAMPILAN MENGGUNAKAN MODEL PEMBELAJARAN PROJECT BASED LEARNING (PJBL) SISWA KELAS VI SDN SUKOREJO 1 KECAMATAN REJOSO KABUPATEN NGANJUK
Authors: Istikakimi Istikakimi , Astuti Wiwik Retno
Published: June 2023

The purpose of this study is to improve the learning outcomes of arts and culture using a project based learning (PJBL) model for sixth grade students at SDN Sukorejo, Rejoso District, Nganjuk Regency. Where this research is a classroom action research which consists of two cycles. Where each cycle includes several stages ranging from planning, implementation, observation, and reflection. The subjects of this study were 19 grade VI students with details of 8 male students and 11 female students. Data obtained from the results of observations, tests, and documentation. Data were analyzed qualitatively and quantitatively with a percentage of completeness of 80%. The results showed that the average value in cycle 1 was 76.74 with details of students who completed as many as 4 and students who had not completed as many as 15 with an achievement percentage of 21.05%. Furthermore, in cycle 2, the average student score was 85.74 with details of students who completed as many as 16 and students who had not completed as many as 2 with an achievement percentage of 84.21%. Based on these results, it can be said that the classical value has been achieved, which is more than 80% in cycle 2. Based on these results, it can be concluded that the project based learning model can be used as an alternative to improve student learning outcomes, especially in learning arts and culture and skills
Optimalisasi Peran Mahasiswa dalam Peningkatan Kewirausahaan Santriwati Melalui Kegiatan Bazar Berkah
Authors: Chodija Mas , Lestari Wahyu Maulida , ZA Mira Wafda Suroiyah , Nuzula Agustin Firdausi , Alfiatuzzahro  , Rachmadani Cahya Ayu , Masruroh Dewi Rifqi , Fauziyah Elly Nur , Safrina Firda , Lailiyah Ifa Zuhriyatul , Khoiriyah  , Musliha Lia , Khosyatillah Sinta Angelina , Nabila  , Arifin Nabilah Khoiriyah , Lailiyah Nofita Nur , Prasti Rosiyya Lafiya Lafika Azka , Aini Siska Nur , Lailiyah Siti Alfinatul , Ilmi Sri Ema Titah Amalia , Rahmah Tsania Muti`ah , Ilahi Nichlatul , Hidayah Siti Novicha , Nabila Maulidia Aliyarana
Published: June 2023

Santriwati needs additional skills in entering the world of society. Santriwati must be able to keep up with technological developments that are growing rapidly to have skills in earning income or income, namely by bazaar activities. This community service aims to increase student entrepreneurship through blessing bazaar activities. Community service is carried out in stages through bazaar activities. The community service partner is the Nurul Ikhlas Islamic Boarding School in Sidoarjo. The results of Community Service obtained are an understanding related to increasing female student entrepreneurship through bazaar activities. Community service through bazaar activities at Islamic boarding schools is to create female students who have an entrepreneurial spirit and can empower their economy independently for themselves and the community.
La relevancia de la educación científica en Hurlingham
Authors: Petrucci Diego , Badagnani Daniel
Published: June 2023

The perceptions that young people have of science and technology, their teaching, and their potential as a life option are decisive both for the choice of related degree programs and for not dropping out of university. In Argentina, the number of graduates in these areas is well below what is needed for national development goals. Knowing those perceptions is important for planning enrollment, retention, and graduation policies. This paper presents data on such perceptions in high school students from Hurlingham, collected through the ROSE questionnaire. The results, in general terms, only differ in specific aspects from those found in other countries. In particular, they present a positive view of science and technology, although with some criticisms, and also a social commitment attitude. This image contrasts with the little enthusiasm and criticism towards school science.
De lo puntual a lo infinito a través de un hilo finito de carga
Authors: Marqués Villarroya David
Published: June 2023

This work shows that the same real physical system can be reduced to a point or infinite system under certain particular conditions. For this, the electric field created by a uniformly charged finite thread is calculated and it is observed that the same real physical system can behave as a point charge or as the opposite, an infinite wire. The objective of this article is to show a practical example of infinite and punctual models in physics for their application in the teaching of pre-universitary physics.
WebQuests como recurso instrucional e avaliativo em Física baseado na teoria da aprendizagem significativa
Authors: Silva Filho Olavo Leopoldino , Ferreira Marcello
Published: June 2023

In the face of repeated findings in academic research and in empirical evidence from teachers and evaluative organizations, the teaching of physics in Brazil has been an object of epistemological, theoretical and methodological concern. In this article, we seek to express a reflection and offer an alternative instructional action based on an interpretation of the Theory of Meaningful Learning, abundant foundation in the area, associated with the use of WebQuests, a didactic and evaluative strategy adherent to contemporary studies on cognition and interactivity with digital information and communication technologies. Evidencing steps of surveying subsumers, advanced organization, progressive differentiation and integrative reconciliation, we document the bases and explore a computational implementation that mimics the aforementioned amalgam and illustrates possibilities for the development of teaching methodologies articulated with interactive digital technologies.
El punto de ebullición: la obstinada persistencia de algunos mitos
Authors: Briozzo Carlos B.
Published: June 2023

The history of the boiling point of water as a thermometric fixed point is an excellent example of how tortuous the real process of building scientific knowledge can be, as opposed to its frequent idealized portrayal as a linear progression. In this article a summary recapitulation is presented, based on the works of researcher and philosopher of science Hasok Chang (Department of History and Philosophy of Science, University of Cambridge), some of its epistemological lessons are discussed, and it is employed to exemplify how the history of science can enrich science education and contribute to eradicate some common misconceptions among the general public and even in the non-specialist scientific community.
Políticas, burócratas y migrantes
Authors: Ramírez Gallegos Jacques
Published: June 2023

El libro Políticas, burócratas y migrantes. Análisis desde la antropología del Estado, editado por el antropólogo Jacques Ramírez Gallegos, cubre principalmente la segunda década del siglo XXI, cuando la política migratoria de Ecuador bascula entre la apertura total de fronteras y el retorno a una política securitista; entre lo que fuera un país donde la inmigración era prácticamente inexistente, y la llegada de chinos, africanos, haitianos, colombianos, cubanos, venezolanos y muchos otros; entre la plasmación del sueño latinoamericano con la libre movilidad, la ciudadanía suramericana que se proponía la Unasur, y las progresivas restricciones y limitaciones a la movilidad, con la irrupción de la migración venezolana, pero que finalmente pudo redistribuirse, en diferentes proporciones, en todo el subcontinente. Esperanzas y crudas realidades que los autores analizan no sólo para el caso de Ecuador, sino para el entorno andino y conosureño, con un enfoque de antropología política, de observación participante y un conocimiento directo del objeto de estudio. El libro tiene la particularidad de articular con maestría y originalidad lo teórico y lo empírico, lo global y lo particular, lo temporal y lo espacial, el Estado y las migraciones. Ofrece en cada capítulo un generoso “estado del arte” (teórico-metodológico y casuístico), que luego es “aterrizado” y sopesado en el análisis específico de los fenómenos abordados, sobre la base de un cotejo con información primaria, cualitativa y cuantitativa, ciertamente indicativa de un fuerte, serio y sostenido trabajo de investigación. Dra. Ana Paula Penchaszadeh