bluuebunny/crossref_metadata_2025 huggingface dataset:
The Ilia A archive
Authors:   , Cecilia Ludovica
Published: December 2023

My research entails the first scholarly edition and study of a Neo-Babylonian private archive, known in literature as the “Ilia A archive”. The archive contains circa 300 cuneiform tablets which were written and stored by the members of a well-to-do family, the Ilia A, who lived in the region of Babylonia during the second half of the first-millennium BCE. The texts record their business and legal interests, as well as their social interactions. Through the complete transliteration and translation of these texts, my research produces a large amount of new data that have been used to conduct an in-depth analysis of the socio-economic conditions in which the family lived, developed their successful careers and created networks of social and business relationships. By adopting the findings on the Ilia A archive as a case study, this research aims to strengthen our knowledge of the socio-economic landscape of first-millennium BCE Babylonia.
Analytical native language education in Vietnam
Authors: Ngu Duong Thi
Published: December 2023

In the goal of comprehensive national development of each country in the world, it is impossible not to mention the task of developing education. In language education, native language education is one of the core issues. Especially in the context that Vietnam is a multi-ethnic country and in the context of a strong integration trend in the world, native language education is becoming more and more urgent. As the national language, Vietnamese language has been promoting its advantages and role in the Vietnamese community. However, as a multi-ethnic country with many ethnic brothers living together, the development of Vietnamese and native languages of ethnic minority communities is a matter of much discussion. In the scope of this article, we present the current situation of native language education in Vietnam.
ESTUDO DA SUBSTITUIÇÃO DE TELAS DE AÇO POR BORRACHA NO FECHAMENTO DO CIRCUITO DE BRITAGEM TERCIÁRIA PARA UM MINÉRIO DE COBRE E OURO
Authors: Da Silva Fagno Gonçalves , Silva Elenice Maria Schons , Silva André Carlos , De Almeida Carlos Alberto Vieira , Evangelista Glauber Julio
Published: December 2023

Este trabalho teve como objetivo apresentar o impacto obtido no peneiramento do circuito de britagem após a substituição das telas convencionais de aço por telas de borracha de uma empresa de mineração que processa minério sulfetado de cobre e ouro situada no município de Alto Horizonte/GO. Trata-se de um estudo de caso, com melhorias significativas no processo entre novembro de 2022 e abril de 2023. O estudo consistiu na realização de testes, coleta de dados e análise estatística, visando avaliar o impacto dessas mudanças na etapa de peneiramento deste circuito. Os principais resultados obtidos foram: aumento da disponibilidade do circuito de 20%, diminuição das paradas por metal em 27% melhorando a utilização e ganhos em valores de 92,49% comparado os dois períodos.
AVALIAÇÃO DO RISCO GESTACIONAL EM PRÉ-NATAL REALIZADO NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Miranda Ruth Andrea Dotta , Do Nascimento Débora Dupas Gonçalves , Duarte Sebastião Junior Henrique
Published: December 2023

O estudo objetivou analisar como é avaliado o risco gestacional em gestantes, com pré-natal realizado na Atenção Primária à Saúde. Pesquisa descritiva, de abordagem quantitativa, realizada com 37 profissionais entre médicos e enfermeiros que realizam assistência pré-natal no município de Corumbá/MS. Um formulário estruturado contendo variáveis definidas pelo Ministério da Saúde, guiou a coleta de dados, no período de maio 2019 a fevereiro 2021. O estudo foi aprovado pelo Comitê de Ética em pesquisas envolvendo seres humanos. Os resultados da observação de 70 consultas de pré-natal mostraram que a prevalência se deu por profissionais do sexo feminino, sendo 85% enfermeiras e 52,9 % médicas, com mais de 10 anos de formação (40,5%). A maioria (72,9%) referiu ter dúvidas para estimar o risco gestacional e 95,7% dos participantes realizou a consulta em menos de 15 minutos. Concluiu-se que os profissionais não seguem todas as recomendações propostas pelo Ministério da Saúde no que se refere a avaliação do risco gestacional, situação que remete a necessidade de educação permanente com foco na assistência pré-natal e a institucionalização de protocolo para padronizar e guiar condutas capazes de oferecer assistência qualificada à gestante e seus familiares.
TRATAMENTO ALTERNATIVO COM CANABIDIOL EM NEOPLASIAS MALIGNAS
Authors: Mineiro Luma Silva , Da Silva Rita de Cassia Santos , Rezende Gabriel de Oliveira
Published: December 2023

Introdução: As neoplasias malignas (câncer) é uma doença multifatorial degenerativa que pode ter diversos fatores. Indivíduos diagnosticados com neoplasia maligna sofrem de sintomas debilitantes causados pela patologia, dependendo do estágio, tipo, invasão de tecidos adjacentes, metástase, tratamento e procedimentos diagnósticos do tumor. Nesse prisma, o uso terapêutico da Cannabis (CB) tem sido objeto de importantes pesquisas científicas em vários países do mundo há muitos anos.  Objetivo: Apresentar os principais benefícios da Cannabis Sativa e seu uso no tratamento no alívio de sintomas causados pelas neoplasias malignas. Metodologia: Trata-se de uma revisão de literatura com abordagem descritiva, serão consultadas as seguintes bases de dados: Scientific Scielo, BVS, Lilacs, Google Schoolar, e acervo da biblioteca setorial da Faculdade Metropolitana de Manaus (FAMETRO). Resultado: CBD tem efeitos não psicoativos, uma vantagem para aplicações clínicas de benefícios antitumorais. O CBD é capaz de interferir em diferentes estágios do processo tumoral, pode inibir migrações e aderências de células cancerígenas e exercer efeitos antiproliferativos, pró-apoptóticos e anti-invasivos. O uso clínico tem crescido gradualmente ano após ano. O CBD apresenta efeitos quimiopreventivas em alguns tipos de câncer, como mama, pulmão, cólon, próstata, pele e cérebro. Considerações finais: E suma, o CBD tem um grande potencial para melhorar a vida dos pacientes com câncer, tanto ao aliviar os sintomas de dor, perturbações do sono e ansiedade, mas também pela atividade sinérgica com tratamentos anticancerígenos para reverter ou eliminar o crescimento de tumores que causam estes sintomas.
The Relationship Between the Severity of Acne Vulgaris and the Quality of Life of Prima Indonesia University Medical Faculty Students
Authors: Serena Putri Ayu Athifa , Natali Oliviti , Mutia Maya Sari
Published: December 2023

Acne vulgaris or acne is a chronic inflammatory disease of the pilosebaceous follicles which is characterized by the appearance of open and closed comedones, papules, pustules, nodules, seborrhea and cysts. Acne vulgaris can occur in teenagers and young adults, such as medical school students, which can affect their quality of life. The aim of this research was to determine the relationship between the severity of acne vulgaris and the quality of life of students. This type of research is analytical observational research with a cross sectional design. The population in this study were students from the Faculty of Medicine, Prima Indonesia University class 2020 – 2021 who suffered from acne vulgaris. The research sample obtained was 38 people. Sampling was purposive sampling. Data was obtained from a questionnaire filled out via the Google Form link. Data were analyzed univariately and bivariately using the Spearman Rho Rank test at a confidence level of 95% (=0.05). The results showed that the severity of acne vulgaris of students at the Faculty of Medicine, Prima Indonesia University students (71.1%) was in the mild category, the quality of life of students was in the mild disorder category (52.6%). The severity of acne vulgaris in students is significantly related to the quality of life of students at the Faculty of Medicine, Prima Indonesia University (p = 0.001 < 0.05), with the close relationship (correlation coefficient) of the two variables in the medium category (r = 0.522).
ANALYSIS OF THE IMPLEMENTATION OF SUSTAINABLE SUPPLY CHAIN MANAGEMENT BASED ON ISPO CERTIFICATION PRINCIPLES IN PALM OIL COMPANIES IN INDONESIA IN 2021
Authors: Nativito Kiva Hartanto
Published: December 2023

Kelapa sawit merupakan salah satu tanaman perkebunan penghasil minyak nabati yang juga merupakan komoditas perkebunan unggulan yang memiliki peran strategis dalam pembangunan ekonomi Indonesia. Pendirian lahan perkebunan kelapa sawit di Indonesia dinilai tidak mengimplementasikan tujuan pembangunan keberlanjutan karena akan merusak lingkungan. Konsumen memberikan tuntutan kepada perusahaan untuk menghasilkan produk dengan proses produksi yang menjaga komitmen berkelanjutan. Sustainable Supply Chain Management (SSCM) adalah manajemen aliran material, informasi dan modal yang merupakan kerjasama antar perusahaan sepanjang rantai pasok dengan mengintegrasikan tujuan-tujuan yang mencakup ketiga dimensi pembangunan berkelanjutan yaitu ekonomi, lingkungan, dan sosial yang dijabarkan dari tuntutan-tuntutan pelanggan dan pemangku kepentingan. Sistem sertifikasi Indonesian Sustainable Palm Oil (ISPO) merupakan prasyarat wajib yang ditetapkan pemerintah untuk perkebunan kelapa sawit untuk memperbaiki tata kelola sawit yang lebih berkelanjutan.
ANALISIS PENGARUH MODAL MANUSIA DAN UPAH MINIMUM TERHADAP KEMISKINAN DI INDONESIA
Authors: Cinta Marito Simbolo  , Fadila Nisa  , Haifa Azalia Pinem  , Haddad Alwi  , Diki Purnomo  , Muammar Rinaldi  , Noni Rozaini
Published: December 2023

Penelitian ini bertujuan untuk menganalisis pengaruh modal manusia dan upah minimum terhadap tingkat kemiskinan di Indonesia tahun 2018-2022. Kemiskinan merupakan salah satu masalah sosial yang sering kali menjadi fokus perhatian dalam pembangunan ekonomi dan sosial suatu negara. Modal manusia, yang mencakup pendidikan dan keterampilan, serta upah minimum, memiliki peran penting dalam mempengaruhi tingkat kemiskinan di suatu negara. Penelitian ini menggunakan data sekunder yang dikumpulkan dari berbagai sumber, termasuk Badan Pusat Statistik (BPS) dan penelitian terkait sebelumnya. Metode analisis regresi data panel digunakan untuk menguji hubungan antara modal manusia, upah minimum, dan tingkat kemiskinan di Indonesia. Hasil penelitian menunjukkan bahwa kesehatan memiliki pengaruh negatif namun tidak berpengaruh yang signifikan terhadap pengurangan tingkat kemiskinan, Pendidikan memiliki pengaruh negatif namun berpengaruh yang signifikan terhadap pengurangan tingkat kemiskinan,  sementara upah minimum memiliki pengaruh positif dan signifikan terhadap pengurangan tingkat kemiskinan yang ada di Indonesia.
RAMAZAN AYI VE SÜRÜ DAVRANIŞI: BORSA İSTANBUL ÜZERİNE BİR ARAŞTIRMA
Authors: TAŞTEMEL Gamze , ÖZKAN Nasıf
Published: December 2023

Bu çalışma, Borsa İstanbul’da Ramazan ayına bağlı sürü davranışının varlığını araştırmaktadır. Bu amaçla çalışmada, 03.03.2014 ile 31.12.2021 tarihleri arasında Borsa İstanbul’da işlem gören 532 payın temettüye göre düzeltilmiş getirileri kullanılmaktadır. Bu veri seti, Chang vd. (2000)’in geliştirdiği getirilerin yatay kesit mutlak sapması (CSAD) metodolojisiyle analiz edilmektedir. İncelenen tarih aralığında Ramazan ayının bütününde, Ramazan ayının farklı günlerinde (ilk, ikinci, son on gün ile son on günündeki tek ve çift sayılı günler) ve bu aydaki farklı piyasa koşullarında sürü davranışına rastlanamamıştır. Ancak, Borsa İstanbul’da Ramazan ayı dışındaki günlerde ve özellikle de yükselen piyasa koşullarında sürü davranışı görülmektedir. Mevcut kanıtların aksine elde edilen bulgular, Borsa İstanbul’da Ramazan ayından kaynaklanan sürü davranışının kalıcı olmadığını göstermektedir.
The Mathematics of Scratch Seven
Authors: Brown Aaron
Published: December 2023

Analyzing a novel card game introduced in a science fiction novel.
Finding Safe Harbor in the Supply Chain: Covid Impact on Market Performance and Market Risk Up and Down the Supply Chain
Authors: Benda Peter
Published: December 2023

Being downstream may offer a safer haven for agile companies to weather supply chain disruptions. Vertically integrated industries may have the highest exposure to supply chain risks.
Covariance and Correlation Swaps in Energy Markets
Authors: Swishchuk Anatoliy
Published: December 2023

Many valuations of variance and volatility derivatives already exist, especially in discrete time, but continuous-time valuations of covariance and correlation swaps do not currently exist for assets following the Heston stochastic volatility model. Energy commodity markets contain some of the broadest and most liquid options markets. Thus, the development of covariance and correlation swap valuation will be of significant use to investors looking to hedge covariance or correlation. In this paper, we derive approximations for an arbitrage-free valuation of natural gas and crude oil covariance and correlation swaps in the Heston model using a continuous-time regime. The approximations are obtained through the use of successive Talyor approximations on otherwise intractable terms. We find that the first order approximations of covariance and correlation swap fair strikes are reasonably effective. When the approximations are taken to the second order, a significant problem with the ML-ARCH approximation of the GARCH(1,1) process creates a large error in the valuation and its error bounds. Leveraging the properties of the Lagrange error bound, we refine our approximation to avoid the use of a frequently miscalibrated parameter, leading to a better approximation of the fair strikes of the two swaps.
Percepção dos discentes sobre as modalidades de ensino em uma instituição de educação superior brasileira
Authors: Siqueira de Oliveira Karla , Picinini Méxas Mirian , Meirelles Drumond Geisa
Published: December 2023

Com o surgimento do surto de Covid-19, em 2020, as Instituições de Ensino Superior (IES) tiveram que tomar medidas rápidas para que pudessem continuar ativas. Neste novo cenário, os docentes tiveram que aprender novas ferramentas para ministrar suas disciplinas online, e os discentes tiveram que se adaptar nesta nova forma de aprender. Dentro dessa realidade, a metodologia adotada neste estudo foi a pesquisa bibliográfica, que teve como objetivo identificar as principais vantagens e desvantagens das modalidades de ensino presencial, remoto e híbrido. Também é considerada uma pesquisa de campo, pois analisou a percepção de 61 discentes de uma IES brasileira sobre as principais vantagens e desvantagens dessas três modalidades. Como resultado, verifica-se que muitas desvantagens apresentadas no ensino presencial correspondem exatamente aos aspectos positivos do ensino remoto, como, por exemplo, no remoto existe a flexibilidade de tempo e horário e a gravação das aulas, o que não ocorre no presencial. Além disso, o ensino híbrido, que combina os benefícios dos ensinos presencial e remoto, pode ser considerado uma nova modalidade para ser adotada no futuro. Espera-se que este estudo possa contribuir com soluções para as desvantagens apresentadas em cada uma das três modalidades de ensino, visando aprimorar todo o processo de ensino-aprendizagem.
Prevenção de deslizamentos se aprende na escola: análise dos resultados do Projeto CEMADEN para a redução de riscos de desastres
Authors: Torres do Prado Gobbo Marcela Regina , Abdala Rachel Duarte
Published: December 2023

As mudanças climáticas são uma realidade percebida em todo o mundo. Podem ter causas naturais ou consequências da ação humana. Nesta pesquisa teve-se o objetivo de investigar a percepção das pessoas envolvidas no Projeto do CEMADEN para a redução de riscos de desastres e para o desenvolvimento da escola cidadã. Trata-se de uma pesquisa qualitativa, com abordagem transversal, e análise documental. Foram realizadas oito entrevistas e, posteriormente analisadas utilizando técnicas de História Oral e triangulação de dados. Concluiu-se que a pandemia covid-19 interferiu no desenvolvimento do Projeto e no seu resultado final. O Projeto foi estendido por mais um ano e as atividades foram retomadas após o mês de outubro de 2022. Os resultados desta pesquisa também revelaram que os jovens que participaram do Projeto e se comprometeram até o final do período, participaram de reuniões e elaboração e todo o processo de dados, alcançaram ótimos resultados escolares, sentiram-se valorizados e participantes de um grupo atuante.
ON THE SOLITARY WAVE SOLUTIONS OF DIFFERENT VERSIONS OF FRACTIONAL 3D- WAZWAZ -BENJAMIN-BONA-MAHONY EQUATIONS
Authors: DEMİRBİLEK Ulviye
Published: December 2023

Nonlinear fractional Wazwaz -Benjamin-Bona-Mahony (WBBM) equations play an important role in physics. The equations form an important model for studying the approximately unidirectional propagation of small amplitude long waves in certain nonlinear distribution systems as an alternative to Kortweg and de Vries (KDV). In this study, the fractional 3D-WBBM equations are solved by using the Improved Bernoulli Sub-Equation Function (IBSEF) method. 3D, 2D and contour plots are given to show the physical properties of the solutions. The main aim of this method is to clarify obvious the exact solutions to the equations. Moreover, the effectiveness of the method is demonstrated by the findings presented in this paper.
KONTEYNER TERMİNALLERİNDEKİ İŞ KAZALARININ BULANIK DEMATEL VE TOPSIS YÖNTEMLERİ İLE İNCELENMESİ: KOCAELİ LİMAN BÖLGESİNDE BİR UYGULAMA
Authors: GÜÇLÜ Kübra , YORULMAZ Murat
Published: December 2023

Uluslararası ticarette denizyolu taşımacılığı diğer taşımacılık türlerine göre birçok avantaja sahiptir. Denizyolu taşımacılığında en çok tercih edilen konteyner taşımacılığı, aynı anda büyük miktarlarda yüklerin güvenilir ve hızlı bir şekilde taşınabilmesini sağladığı için konteyner terminallerindeki gemi ve yük trafiği yoğun olmaktadır. Konteyner terminalleri, yükün konteynerler aracılığıyla taşındığı karayolu, demiryolu ve denizyolu arasındaki ara yüzdür ve bünyesinde birçok riski bir arada bulundurmaktadır. Dolayısıyla iş kazalarını ve yaralanmaları önleyebilmek adına iş sağlığı ve güvenliği yönetim sistemlerinin çalışma alanına taşınması önemli bir husustur. Bu kapsamda bu çalışmanın amacı, konteyner terminallerinde yaşanan iş kazalarının nedenlerinin belirlenmesi ve iş kazalarının önlenmesine yönelik alınabilecek önlemlerin tespit edilmesidir. Bu çalışmada, konteyner terminallerinde yaşanan iş kazaları nedenleri kriterler ve alt kriterler olarak değerlendirilmiş ve bulanık DEMATEL yöntemi ile analiz edilmiştir. Ardından konteyner terminallerinde yaşanan iş kazalarını önleyebilmek adına belirlenmiş alternatifler TOPSIS yöntemi ile analiz edilerek önem derecesine göre sıralanmıştır. Yapılan analizlerin sonucunda, konteyner terminallerinde yaşanan iş kazalarının nedenleri arasında “yönetim uygulamaları kaynaklı” iş kazalarının ilk sırada geldiği tespit edilmiştir. Alternatif önlemlerin sıralamasında ise “iş sağlığı ve güvenliği denetimlerinin etkinliğinin arttırılması” en ideal çözüm olarak belirlenmiştir.
ALPHAFOLD: DERİN ÖĞRENME VE SİNİR AĞLARI YOLUYLA PROTEİN KATLAMASINDA DEVRİM YARATMAK
Authors: TEKİN Burcu , GURBANOV Rafig
Published: December 2023

AlphaFold, bir protein dizisinin üç boyutlu yapısını tahmin etmek için derin sinir ağlarını ve gelişmiş makine öğrenimi tekniklerini kullanan, DeepMind ekibi tarafından geliştirilmiş bir protein katlama tahmin aracıdır. Protein katlanmasının tahmini, hesaplamalı biyolojide uzun süredir devam eden bir sorun olmuştur ve doğru protein yapısı tahmin yöntemlerinin geliştirilmesi, bilim camiasının büyük ilgisini çekmiştir. AlphaFold, önce bir proteinin yerel yapısını tahmin ettiği ve ardından genel yapıyı bir araya getirdiği iki aşamalı bir yaklaşım kullanır. AlphaFold, iki yılda bir yapılan CASP (Yapı Tahmininin Kritik Değerlendirmesi) deneylerinde diğer son teknoloji yöntemleri geride bırakarak çok çeşitli proteinlerin yapısını tahmin etmede kayda değer bir başarı elde etmiştir. AlphaFold'un tahminlerinin doğruluğu, protein işlevini ve hastalık mekanizmalarını, ilaç keşfini ve sentetik biyolojiyi anlamak için önemli etkilere sahiptir. Bu derlemede, AlphaFold'un geliştirilmesine, temel metodolojisine ve CASP deneylerindeki performansına genel bir bakış sunulmaktadır. Ek olarak, AlphaFold'un protein mühendisliği, ilaç keşfi ve yapısal biyolojideki potansiyel uygulamaları da tartışılmaktadır.
Utilization of Abandoned Land Based on Regulation of the Minister of Environment and Forestry Number 07 of 2021 for Food Estate
Authors: Panglima Rubby Aditya , Lie Gunardi
Published: December 2023

Basic Agrarian Law no. 5 of 1960 stipulates that all land rights must have a social function, by Article 6 which states that land cannot be used solely for personal interests, especially if this is detrimental to society. Land use must be adapted to conditions and rights, providing benefits both for the owner & for the community and state. Abandoned land, including land rights, Management Rights, and land based on a Land Tenure Basis that is not used or cultivated, is the focus of this research. This research aims to explain the relationship between the 1960 Basic Agrarian Law regarding abandoned land and its derivative regulations, especially in the context of the National Food Estate Strategic Program. The research method uses secondary data with a normative juridical approach to synchronize legal provisions with field practice. Social Function is identified as an integral element in Land Rights, and the author believes that abandoned land, such as Cultivation Rights, can be used for the prosperity of the people. However, Minister of Environment and Forestry Regulation no. 07 of 2021 indicates that these social functions have not been fully utilized along with other land uses, creating inconsistencies in the implementation of the policy.
Diction problems and their solution in Nordic lied
Authors: Lupu Simion Sorin
Published: December 2023

The article represents a research of the problems related to the diction in the Nordic lied, determined by the peculiarities of the North Germanic and Finno-Ugric languages and their solution. Given that the musicians chosen for the present research composed on lyrics written in the Swedish, Danish, Norwegian and Finnish languages, we focused mainly on the pronunciation in these languages. Thus, the euphonic differentiation of the vowels compared to the repertoire approached so far (in Italian, French, German, English and Spanish), represents the main difficulty in performing the Nordic lied. Solving some difficulties of pronunciation, articulation, impostation, dosage or expressiveness, have proven to be of real use in approaching the repertoire in the above-mentioned languages, and the problems raised by phonetic and linguistic peculiarities of the Nordic languages have motivated the identification of arguments, solutions and sometimes novel but functional solutions.
Aspects of creation portrait of a teacher Ion Radu
Authors: Dermenji Igor
Published: December 2023

The article illustrates some biographical moments from the life and activity of Ion Radu, an accordionist and teacher at the Department of Folk Instruments at the College of Music and Pedagogy from Balți. The author presents his contribution to the training and development of the interpretive mastery of the students in the accordion class at the college, and also the rise of the professional activity and his major contribution to the enrichment of the accordion repertoire through numerous transcriptions for this instrument. At the same time, Ion Radu also promotes the folklore traditions, collecting about 150 folk songs from the Danube Bugeac, most of them being presented in the collection of folkloric works „Chiti, Miti”, thus demonstrating the continuity and viability of the local musical folklore.
Cinematic discourses in the attitudinal mode
Authors: Olarescu Dumitru
Published: December 2023

In the creation of director Vlad Druc, a special place belongs to cinematographic discourses in which various existential, moral, spiritual and psychological problems, frequently encountered in our society, are addressed. The problem-films will serve as arguments: Native Land, Renaissance, Today in the Evening, Your Child, I Am Waiting for You, Vive la Femme!, Nakedness, Alternations, Frontiers, etc. These films, with a wide thematic range, stand out through their journalistic nerve and through a pronounced spirit of investigation, elucidating the civic position, the deep attitudinal mode and the concern of the filmmaker Vlad Druc towards the problems of our society, expressing them masterfully through cinematic language.
The stage name and protected music trademark: analysis of music branding in the Republic of Moldova
Authors: Badicu Iurie
Published: December 2023

This research highlights the importance of the protected stage name in the development of the music industry and provides an answer to the question: out of all the protected trademarks in the world, what is the total number of music brands in the Republic of Moldova and what exactly are they? The author carried out a research where he performed a staged and complex analysis of local music branding. The protected and representative stage names for the music industry in the Republic of Moldova during the period between 2012 and 2021 were fully investigated. In order to record a quantitative, qualitative, significant and up-to-date result, the author combined several research methods and methodological principles, applying the following validation criteria to trademarks: validity, representativeness, capitalization, valorization, social connection, professional connection and the criterion of belonging to the musical industry from the Republic of Moldova. In order to avoid errors, classified, grouped, encrypted, structured and coded databases of different representative entities were contrasted and compared. The author concludes considering that the protected music brand ensures the development of the local music industry and exerts a significant cultural and economic impact, thus contributing to the development of culture and society in the Republic of Moldova. By highlighting the importance of the cultural approach to the protected stage name, research represents a novelty in the field of the study of culture, public and private artistic management.
Presentación. Nación y catolicismo en el siglo XIX
Authors: Ramón Solans Francisco Javier
Published: December 2023

Durante mucho tiempo nación y religión han sido analizadas como dos realidades incompatibles cuando no antagónicas. Frente a estas visiones dicotómicas, en los últimos años la historiografía ha mostrado la diversidad de formas en las que ambos elementos se conjugaron. Este dosier aborda las diferentes formulaciones y declinaciones, los puntos de encuentro y las tensiones entre nación y catolicismo en Europa y América Latina en el siglo xix.
The offense of violating the legal provisions regarding the conflict of interests in the case of companies with legal personality
Authors: Vîrjan Bogdan
Published: December 2023

At the conflict of interests designates, in the general sense, that situation in which, when making a decision or participating in the deliberation process for making a decision, a person has a personal patrimonial interest that may have influence regarding the objective fulfillment of the duties assigned to him according to the legislation in force.

Both in European and domestic legislation, when the conflict of interests is regulated, a distinction is made between persons exercising public dignities and offices and persons exercising their duties within companies with legal personality in the private sector. Of course, in the case of persons who exercise certain dignities or public offices, the principle of the supremacy of the public interest must be respected, which is why, in the case of these persons, the legal regime of the conflict of interests is much more restrictive, unlike the case of persons who carry out their activity in the private sector, in which case they receive the interest of the legal entity within which they exercise their duties. In other words, a distinction must be made between conflict of interests in the public domain and conflict of interests in the private domain.

Considering the particularities and special importance of the legal regime regarding the conflict of interests in the private field, this paper proposes a detailed analysis of the way in which criminal protection is provided to the legal regime regarding the conflict of interests in the case of companies with legal personality. A clarification is made of the notions of incompatibility, indignity and conflict of interests, by highlighting the common characteristics and aspects that differentiate these notions, highlighting the particularities of the way of criminalizing the conflict of interests in the domestic legislation.
Omgaan met onzekerheid in cross-sectorale infrastructuurprojecten
Authors: Røsok Oddrun , de Bruijne Mark , Veeneman Wijnand
Published: December 2023

Dealing with uncertainty in cross-sectoral infrastructure projects

Infrastructure managers increasingly face scarcity in terms of the capacity to develop their infrastructure networks. New projects face significant limitations, in terms of maintenance and renewal as well as the development of new infrastructures. A logical next step from a project perspective is so-called cross-sectoral infrastructure projects. In this article, we assess the consequences of working in cross-sectoral infrastructure projects. Recent findings from an in-depth case study of a cross-sectoral infrastructure project suggests that working in these projects is not simply ‘more of the same’ in terms of task execution and project management. Instead, practitioners need to adjust their forms of collaboration and communication with practitioners from other infrastructure operators. The focus of attention shifts from the management of risks and the environment to the joint exploration of uncertainties in the environment in the early phase of infrastructure development projects.
Verkennen en verleggen van infrastructuurgrenzen
Authors: Toering Arnoud , de Bruijne Mark
Published: December 2023

Exploring and expanding infrastructure boundaries: A closer look at the development of strategic decision-making for infrastructure and the role of infrastructure managers

The focus on sustainability has contributed to a new outlook on how to shape the fabric of our society: infrastructure. New strategic decision-making structures have developed to decide on the future of infrastructures, which include more as well as more varied actors, such as societal and governmental actors (i.e. local and regional governments). The new structures are redrawing the boundaries of infrastructure governance. In these processes, infrastructure managers arguably play a crucial, yet less well-understood role. Three examples of strategic infrastructure processes are discussed, which highlight how, from uniquely different starting points, infrastructure managers play a different role in the strategic decision-making processes. The precise form and focus of the new coordination and decision-making structures will take shape in the coming years. Insight in these developments and their influence on infrastructure planning enables us to assess how and to what extent the ‘openness’ of infrastructure managers in infrastructure planning influence strategy processes and contribute to more integral assessment and synergy.
Over versterking van constitutionele toetsing in het wetgevingsproces
Authors: van Sasse van IJsselt P.B.C.D.F.
Published: December 2023

Over versterking van constitutionele toetsing in het wetgevingsproces

Constitutionele toetsing ex ante en ex post zijn nauw met elkaar verbonden. In deze bijdrage neemt de auteur de vraag ter hand of, en zo ja, wat nodig is om de constitutionele toetsing in het wetgevingsproces te versterken. Hij concludeert dat er al een fors aantal (constitutionele) toetsinstrumenten en -momenten van ontwerpwetgeving bestaat, en dat de belangrijkste winst zal zitten in een breedgedragen attitude en aanvaarding dat constitutionele toetsing een ambacht is dat tijd en aandacht vergt, waarvoor capaciteit en prioriteit aanwezig moeten zijn bij de relevante organisaties. Daarvoor is onderhoud en/of (door)ontwikkeling van een constitutionele cultuur een vereiste.
Constitutionele toetsing in Armenië
Authors: Karapetian G.
Published: December 2023

Constitutionele toetsing in Armenië

In deze bijdrage wordt aandacht besteed aan constitutionele toetsing door het Armeense Constitutioneel Hof. Hoe is constitutionele toetsing in het Armeense staatsrecht vormgegeven? Aan welke bepalingen wordt er getoetst en wanneer? Wie legt de vragen voor aan het Constitutioneel Hof in Yerevan en wat zijn de rechtsgevolgen van zijn oordeel? Indachtig de hoofdlijnenbrief constitutionele toetsing van 1 juli 2022 worden enkele verschillen en overeenkomsten tussen het voorstel van het kabinet-Rutte IV en de Armeense constitutionele toetsingspraktijken bezien.
Dynamical analysis of a chemostat model for 4-chlorophenol and sodium salicylate mixture biodegradation
Authors: Dimitrova Neli
Published: December 2023

We consider a mathematical continuous-time model for biodegradation of 4-chlorophenol and sodium salicylate mixture by the microbial strain Pseudomonas putida in a chemostat. The model is described by a system of three nonlinear ordinary differential equations and is proposed for the first time in the paper [Y.-H. Lin, B.-H. Ho, Biodegradation kinetics of phenol and 4-chlorophenol in the presence of sodium salicylate in batch and chemostat systems, Processes, 10:694, 2022], where the model is only quantitatively verified. This paper provides a detailed analysis of the system dynamics. Some important basic properties of the model solutions like existence, uniqueness and uniform boundedness of positive solutions are established. Computation of equilibrium points and study of their local asymptotic stability and bifurcations in dependence of the dilution rate as a key model parameter are also presented. Thereby, particular intervals for the dilution rate are found, where one or three interior (with positive components) equilibrium points do exist and possess different types of local asymptotic stability/instability. Hopf bifurcations are detected leading to the occurrence of stable limit cycles around some interior equilibrium points. A transcritical bifurcation also exists and implies stability exchange between an interior and the boundary (washout) equilibrium. The results are illustrated by lots of numerical examples.
Anais do XV Encontro Estudantil e XV Workshop de Enfermagem
Authors: Fundação Herminio Ometto Centro Universitário da
Published: December 2023

Anais do XV Encontro Estudantil e XV Workshop de Enfermagem
Apoptosis in relation to neuronal loss in experimental Creutzfeldt-Jakob disease in mice
Authors: Jesionek-Kupnicka D , Kordek R , Buczyński J , Liberski P P
Published: December 2023

Apoptosis constitutes a genetically determined process to eliminate superfluous or damaged cells in tissues. Deficiencies in apoptosis regulation are involved in different pathologies including prion diseases. Some experimental studies show that neuronal loss - one of the hallmarks of prion diseases may be accomplished by apoptosis. We evaluated twenty five mice infected experimentally with the Fujisaki strains of CJD and sacrified sequentially in one week intervals. Apoptotic cells in various brain regions were detected by in situ end labelling (TUNEL) and electron microscopy in comparison with neuronal cell loss. The number of labelled cells per brain as
very low - from a few labelled cells 6 weeks after inoculation to a maximum of 14 in the terminal stage. The number of neurones counted in 8 selected areas were considerably lower in terminally sick animals (20 and 21 week of incubation period) than in control mice. The mean value of loss of neuronal cells was 32%. The greatest loss (55%) of neurones was noted in the septal nuclei of the paraterminal body and the least lost (16%) in the hypothalamus. Compared to the extensive neuronal loss (30-50%), the number of apoptotic cells detected by in situ end labelling seems to be very low, and the process of neuronal death become more intensive during the progression of the disease.
In vitro pituitary prolactin, growth hormone and follicle stimulating hormone secretion during sexual maturation of female rats primed with melatonin
Authors: Díaz Rodríguez E , Fernández Alvarez C , Castrillón P O , Esquifino Parras A I , Díaz López B
Published: December 2023

The influence of in vivo melatonin administration on in vitro pituitary follicle stimulating hormone (FSH), growth hormone (GH) and prolactin secretion, as well as the possible influence of dopamine (DA) were evaluated in prepubertal (31-day-old), pubertal (33-day-old) and adult female rats at diestrus phase of the sexual cycle. The in vitro pituitary hormone secretions were evaluated at basal rate for the first hour of incubation only, in Krebs Ringer phosphate (KRP) (I1) and after a second hour of incubation with KRP (I2) or with KRP+DA (I 2 plus DA). I1 PRL secretion was significantly higher in 33-day-old control and melatonin treated (MEL) rats as compared to I 2 periods. However, in 31-day-old rats I1 secretion was higher than in the I2 or I 2+DA periods, in MEL rats. In vitro GH secretion was significantly higher at I1 than during I 2 periods in the control 31- and 33-day-old groups, but not in MEL rats. The only significant effect of DA was the elevation of GH in prepubertal MEL rats. In vitro FSH release was increased by melatonin in 31-and 33-day-old female rats. No differences in PRL, GH and FSH secretion were found in adult rats. In conclusion, the results show that melatonin effects upon in vitro pituitary gland activity are reproductive-stage-dependent modifying the secretory capacity of the lactotrop, gonadotrop and somatotrop during prepubertal and pubertal ages but not in adult rats studied at a quiescent phase of the sexual cycle.
Sulfurtransferase activity and sulfur compound content in Rana temporaria brain following hibernation
Authors: Wróbel M
Published: December 2023

The activity of rhodanese, 3-mercaptopyruvate sulfurtransferase and gamma-cystathionase and the content of glutathione and sulfane sulfur compounds were determined in Rana temporaria brain in April. The high sulfane sulfur level observed in the spring seems to be associated with protection against cellular oxidative stress after the period of hibernation with its minimal
oxidative metabolism.
The influence of lidocaine on the permeability of the blood-cerebrospinal fluid barrier in experimental acute hypercapnia in the rabbit
Authors: Naskret M , Płatkiewicz M , Billert H , Drobnik L , Dyderski S
Published: December 2023

In a previous study we have provided evidence, that acute experimental hypercapnia due to hypoventilation in the rabbit alters blood-cerebrospinal fluid barrier function in the brain (Pakulski et al. 1998). The purpose of this study therefore was to determine if lidocaine would prevent the observed alterations in the blood-cerebrospinal fluid barrier function. The experiments were conducted in 16 adult Chinchilla rabbits submitted to acute hypercapnia due to mechanical hypoventilation (PaCO2 between 8 - 9.5 kPa over 180 minutes) under pentobarbital anaesthesia. The studied group (n = 8) was treated by lidocaine infusion 10 mg kg-1h-1. After 180 minutes of hypercapnia the value of cerebrospinal fluid-blood index of gentamycin concentration, indicating the permeability of the blood-cerebrospinal fluid barrier, was significantly lower in animals treated with lidocaine (4.03+/-2.32 vs. 19.05+/-5.49; P< 0.01). We conclude that lidocaine may attenuate the increase of blood-cerebrospinal fluid barrier permeability under conditions of experimental acute hypercapnia lasting 180 minutes in the mechanically ventilated rabbit.
Postural stability and fractal dynamics
Authors: Błaszczyk J W , Klonowski W
Published: December 2023

Methods of non-linear dynamics and deterministic chaos may provide us with effective quantitative descriptors of the dynamics of postural control. The goal of this study was to introduce a new measure, which would allow to determine the fractal structure of posturographic signals and to measure the effect of the loss of visual feedback information in postural control. The results of the study show that fractal dimension (Df) is a very useful, reliable and sensitive measure of the complexity of posturographic signals. Therefore Df can be used for the evaluation of postural stability and its changes due to pathology or an age-related decline.
Effect of posterior hypothalamic injection of procaine on the hippocampal theta rhythm in freely moving cats
Authors: Bocian R , Konopacki J
Published: December 2023

Earlier in vivo studies conducted on freely moving and anesthetized rats demonstrated that the posterior hypothalamus (PH) comprises pathways critical for producing the synchronous hippocampal formation (HPC) theta rhythm. In addition, these findings suggested that the frequency of the HPC theta was encoded in the PH and then was fed via the medial forebrain undle
to the medial septum and HPC. In the present study we attempted to verify his hypothesis with use of a different in vivo model - freely moving cats. The microinjection of the local anaesthetic, procaine, into the PH region reversibly
suppressed the spontaneous as well as sensory and electrically induced HPC theta. However, in contrast to rats, in freely moving cats microinjection of procaine into the PH reduced the amplitude of the HPC theta but had no effect on theta frequency. We conclude that in freely moving cats the PH region comprises a critical part of the ascending brainstem pathway, for production of the HPC theta rhythm. In contrast to rats, in freely moving cats ascending inputs from the brainstem to the PH contribute mainly to the amplitude of the HPC theta rhythm.
Application of infrared detection in the recording of eylid movements in rabbits
Authors: Orłowska-Majdak M , Kołodziejski P , Dolecki K , Traczyk W Z
Published: December 2023

Classical conditioning of the eyelid reflex has been used for a long time to study associative learning in animals and humans. A new experimental procedure for rabbit’s eyelid conditioning was constructed and described. A phonopneumatic stimulator generated conditioned and unconditioned stimuli
and a photoelectric transducer acting in close infrared converted movements of rabbits’ eyelid to electric signals. An example of acquisition and extinction
training is illustrated. This method of eyelid movement monitoring is noninvasive. It may be useful for chronic studies of learning processes in rabbits when used with headpieces for microdialysis probes, electrodes or cannulas which could be implanted into brain structures.
Unbiased high resolution method of EEG analysis in time-frequency space
Authors: Blinowska K J , Durka P J
Published: December 2023

Matching Pursuit (MP) - a method of high-resolution signal analysis - is described in the context of other methods operating in time-frequency space. The method relies on an adaptive approximation of a signal by means of waveforms chosen from a very large and redundant dictionary of functions.
The MP performance is illustrated by simulations and examples of sleep spindles and slow wave activity analysis. An improvement of the original procedure, relying on the introduction of stochastic dictionaries, is proposed. A comparison of the performance of dyadic and stochastic dictionaries is presented. MP with stochastic dictionaries is characterized by an unmatched resolution in time-frequency space; moreover it allows for parametric description of all (periodic and transient) signal features in the framework of the same formalism. Matching pursuit is especially suitable for analysis of non-stationary signals and is a unique tool for the investigation of dynamic changes of brain activity.
Reduced degree of long-range phase synchrony in pathological human brain
Authors: Bhattacharya J
Published: December 2023

In this paper multivariate spontaneous EEG signals from three broad groups of human subjects - control, seizure, and mania - were studied with the aim of investigating the possible effect of these pathologies on the degree of phase synchronization between cortical areas. The degree of phase synchrony was measured by two recently developed measures which are more suitable than classical indices like correlation or coherence when dealing with nonlinear and non-stationary signals like the EEG. Signals were reduced to seven frequency bands (delta, theta, alpha-1, alpha-2, beta-1, beta-2 and gamma) which were statistically compared between the normal and the other two groups. It was found that the degree of long-range synchrony was significantly reduced for both pathological groups as compared with the control group. No clear differences were found in the degrees of short-range synchrony.
Proteolysis of endomorphin-1 by brain synaptic membrane-associated peptidases
Authors: Wu Liming , Chen Junhui , Zhong Dulai , Lin Chentao , Wang Xingchang
Published: December 2023

The biotransformation of endomorphin-1 (EM-1) by brain synaptic membranes has been studied. Peptide fragments of EM-1 that were formed during incubation with membrane preparations in vitro were isolated by High-performance liquid chromatography (HPLC) and characterized using determination of amino acid composition. At pH 7.4, two degradation products, EM-1(1-3) and EM-1(1-2), were identified. EM-1 was degraded 77.5% at 30 min incubation with synaptic membranes. The time course of the experiments and the effect of carboxypeptidase inhibitor (CPI) demonstrated that the proteolysis reaction involves the participation of carboxypeptidase activity.
Superior laryngeal nerve section abolishes capsaicin evoked chemoreflex in anaesthetized rats
Authors: Kaczyńska Katarzyna , Szereda-Przestaszewska Małgorzata
Published: December 2023

Respiratory effects of an intravenous injection of capsaicin were investigated in nine vagotomized and subsequently laryngeally deafferentated, urethane- and chloralose- anaesthetized and spontaneously breathing rats. Bolus injection of capsaicin (5 mmg/kg) into the right femoral vein induced an expiratory apnoea of 4.23 +/- 0.63 s duration (mean +/- SEM). In post-apnoeic breathing, tidal volume increased by 14% from the control level (P
Drug addiction as drive satisfaction ("antidrive") dysfunction
Authors: Kostowski Wojciech
Published: December 2023

Drug addiction is a complex brain disorder, characterized by the loss of control over drug seeking and drug taking behavior, and by the risk of relapse, even after a prolonged period of abstinence. This disorder may have its source in a disturbed balance of drive-related behaviors, which control appetitive reactions aimed at seeking contact with an addictive substance. The act of consumption becomes more and more attractive, and the behavior takes on compulsive character. We suppose that drug addiction may involve a change in the mechanism of satisfaction of drives and states of satiation as well. To understand how the motivational processes are changed with the development of dependence, one must consider the mechanism of drive satisfaction and satiation states that occur in relation to the consumatory reflex. When a given drive is satisfied a state of fulfilment occurs. This state may be a result of a so-called "antidrive" mechanism (Konorski 1967). While a drive activity is characterized by general activation and tension, the drive satisfaction state ("antidrive") is characterized by relaxation and relief. When a particular drive is satisfied, the operation of other drives become possible. Therefore, we postulate that dysfunction of drive satisfaction leads to the sustained activation related to the current drug-related drive, which blocks the operation of other drives. In effect, uncontrolled compulsive appetitive behavior is released, and the operation of other drives is restrained, thus forcing the organism to focus on drug-related drive. The reason for an "antidrive" dysfunction may be related to adaptive changes which develop during a contact with an addictive substance.