bluuebunny/crossref_metadata_2025 huggingface dataset:
A Through-Intact-Skull (TIS) chronic window technique for cortical structure and function observation in mice
Authors: Li Dongyu , Hu Zhengwu , Zhang Hequn , Yang Qihang , Zhu Liang , Liu Yin , Yu Tingting , Zhu Jingtan , Wu Jiamin , He Jing , Fei Peng , Xi Wang , Qian Jun , Zhu Dan
Published: September 2022

Modern optical imaging techniques provide powerful tools for observing cortical structure and functions at high resolutions. Various skull windows have been established for different applications of cortical imaging, and each has its advantages and limitations. Most critical of the limitations, none of the current skull windows is suitable for observing the responses to some acute craniocerebral injuries on a large scale and at high resolution. Here, we developed a “Through-Intact-Skull (TIS) window” that enables the observation of an immune response on a bilateral cortical scale and at single-cell resolution after traumatic brain injury without affecting the pathological environment of the brain. The TIS window also has the advantages of craniotomy-freeness, centimeter-field of view, synaptic resolution, large imaging depth, long-term observation capability, and suitability for awake mice. Therefore, the TIS window is a promising new approach for intravital cortical microscopy in basic research in neuroscience.
European Psychiatric Association guidance on treatment of cognitive impairment in schizophrenia
Authors: Vita Antonio , Gaebel Wolfgang , Mucci Armida , Sachs Gabriele , Barlati Stefano , Giordano Giulia Maria , Nibbio Gabriele , Nordentoft Merete , Wykes Til , Galderisi Silvana
Published: September 2022

Background

Although cognitive impairment is a core symptom of schizophrenia related to poorer outcomes in different functional domains, it still remains a major therapeutic challenge. To date, no comprehensive treatment guidelines for cognitive impairment in schizophrenia are implemented.

Methods

The aim of the present guidance paper is to provide a comprehensive meta-review of the current available evidence-based treatments for cognitive impairment in schizophrenia. The guidance is structured into three sections: pharmacological treatment, psychosocial interventions, and somatic treatments.

Results

Based on the reviewed evidence, this European Psychiatric Association guidance recommends an appropriate pharmacological management as a fundamental starting point in the treatment of cognitive impairment in schizophrenia. In particular, second-generation antipsychotics are recommended for their favorable cognitive profile compared to first-generation antipsychotics, although no clear superiority of a single second-generation antipsychotic has currently been found. Anticholinergic and benzodiazepine burdens should be kept to a minimum, considering the negative impact on cognitive functioning. Among psychosocial interventions, cognitive remediation and physical exercise are recommended for the treatment of cognitive impairment in schizophrenia. Noninvasive brain stimulation techniques could be taken into account as add-on therapy.

Conclusions

Overall, there is definitive progress in the field, but further research is needed to develop specific treatments for cognitive impairment in schizophrenia. The dissemination of this guidance paper may promote the development of shared guidelines concerning the treatment of cognitive functions in schizophrenia, with the purpose to improve the quality of care and to achieve recovery in this population.
A national survey of the radiotherapy dosimetrist workforce in the UK
Authors: Blackler Nicola , Bradley Karen E , Kelly Charles , Murphy Steven , Cross Carole , Kirby Mike
Published: September 2022

Objectives:

To undertake a national survey of the Radiotherapy Dosimetrist workforce within the UK; examining different attributes and experiences, comparing results with published evidence within the literature.

Methods:

A national, anonymised survey was undertaken between Dec 2020 and end of Feb 2021; employing a mixed-methods approach and blend of closed, open-ended answer choices and free-text comments. Questions included range of training routes and job titles; registration status; job tasks and engagement with Continuing Professional Development (CPD).

Results

A total of 223 individuals responded. Nearly half were trained via therapeutic radiography; approximately, a fifth through a clinical technologist/physics routes. Most (70%) had Dosimetrist in their job title. Nearly 70% were statutorily registered, and almost a fifth were in the voluntary register of Clinical Technologists. Most job tasks were in treatment planning – with 57% spending over 70% of their time there. Most notably, 29% were not involved in any CPD scheme. No published evidence showed the same aspects identified here.

Conclusions:

Our survey showed a unique profile of the Radiotherapy Dosimetrist workforce in the UK, with a variety of training routes and statutory registration status. Nearly, a third were not engaged in a CPD scheme – adding to the current discussion that perhaps all Dosimetrists should be statutorily registered, for ensuring safe and effective clinical practice.

Advances in knowledge:

A novel and unique national survey of Dosimetrists working in Radiotherapy in the UK is presented, leading to new insights into current training routes, registration status, job tasks and CPD engagement and needs.
Clarification the Current Situation of Deterioration and Its Causes of Modernization Heritage Built with Bricks in Japan: A Case Study of Long-Term Monitoring Investigation at Sarushima Battery, Yokosuka, Japan
Authors: Fukami Risako , Matsui Toshiya , Kawamoto Mayumi
Published: September 2022

A long-term monitoring investigation at Sarushima Battery (Kanagawa, Japan), which is one of the modernization heritages was conducted from 2017.06 to 2020.12. The investigation of the temperature and relative humidity (RH), measurement of the amount of brick decay, and X-ray diffraction analysis of the brick decay was conducted to understand in detail the environment in which the historical brick structure, the state of deterioration, identify the factors of deterioration. Furthermore, it was discussed whether the suitability of these investigation methods for assessing the status, identifying the level of deterioration and the factors that led to deterioration at the historical brick heritages. It was found that the brick deterioration at the site progressed especially in two periods: in April, and from June to August. These periods coincided with the period when the RH inside the structure decreased, and the Toyo-gumi bricks were in the process of absorbing moisture. Several different types of salts were detected in brick decay, especially thenardite, which is considered highly hazardous and destructive during periods when the amount of brick decay increased. Therefore, the RH in the structure and the salts present in the bricks were identified as one of the factors in the deterioration of the bricks at the site. The methods used in this study are appropriate as the initial survey methods for investigating the current conditions and identifying the causes of deterioration because it is possible to understand the environment within the modernization heritages, grasp the details of deterioration progression, and identify the characteristics of deterioration progression and its factors through long-term investigation using the simple methods.
Changes of Physical and Chemical Properties for Making Raw Materials and Reproductions According to Manufacturing Stages in Traditional Korean White Porcelain
Authors: Kim Du Hyeon , Jeong Ji Youn , Oh Eun Jeong , Han Min Su
Published: September 2022

We made a Korean white porcelain or Joseon Baekja jar and based on the raw materials used and reproductions of each stage, we aimed to compare and analyze the physicochemical changes of the raw materials such as clay at each manufacturing stage, as well as identify the characteristics and correlations. Although the basic main components of clay and glaze material are similar, their texture becomes denser in the process of bisque firing pottery (Chobeol-pyeon) and glaze firing pottery (Jaebeol-pyeon), and we confirmed that in addition to the tendency of increasing vitrification, low-temperature minerals such as mica and illite gradually disappeared, while high-temperature minerals such as cristobalite were newly created. This phenomenon has also been verified by the rapid decrease in absorption rate while the change in specific gravity was small. In addition, the color was greatly affected by the firing atmosphere, and the yellow-red chromaticity of the raw materials was higher during bisque firing but showed a rapidly decreasing characteristic during glaze firing. The value of magnetic susceptibility, which is related to iron (Fe) component, showed a tendency to decrease in glaze firing pottery. CT images were confirmed as a method that can indirectly estimate the change in the material properties of the object step-by-step for the entire object. In conclusion, the study of manufacturing stages of reproduction can provide basic data for scientific research on the estimation of porcelain and pottery making technology and changes in raw materials.
Conservation Status Diagnosis of Mural Painting in Geungnakjeon Hall of Daewonsa Temple, Boseong: Avalokitesvara Bodhisattva Mural and Buddhist Monk Bodhidharma Mural
Authors: Lee Hwa Soo , Eom Tae Ho , Jee Bong Goo , Yi Sun Jo , Yu Yeong Gyeong , Han Kyeong Soon
Published: September 2022

Investigation of conservation status, optical survey, infrared thermography, and ultrasonic examination were performed on Avalokitesvara Bodhisattva mural and Buddhist Monk Bodhidharma mural to determine the conservation status and physical properties. As a result of investigation of conservation status, the types of damage are largely divided into the wall and finishing layer damage, painting layer degradation, damage due to restoration materials, stains and contamination, and biological damage. As a result of the optical survey, drawing, stains, and repainted site were confirmed. Result of the infrared thermography, the delamination of the finishing layer was confirmed, and some locations and shapes of the wooden lath inside the wall were identified. The result of the 3D scanning, the deviation, and the separation of the wall was confirmed. As a result of ultrasonic examination, it was confirmed that the physical properties of the mural were identified and the ultrasonic speed was relatively low due to physical damage such as delamination and exfoliation of the finishing layer and cracking. Ultrasonic speed values were also high in some wall cracks or delamination, and it was confirmed by the infrared thermography results that the wooden lath inside the wall was located in those parts. It was possible to understand that the wooden lath inside the walls affects the ultrasonic speed during the ultrasonic examination. Therefore, management through periodic inspection of the relevant elements is necessary, and a countermeasure for damage that may occur in the future should be prepared along with intensive monitoring of the major damage identified in this diagnosis result.
Early biofouling colonization stages: Implications for operation and maintenance planning in marine renewable energy projects
Authors: Vinagre Pedro Almeida , Fonseca Gonçalo
Published: September 2022

Background:Marine biofouling is a threat to industries working in the marine environment, representing enormous costs associated with equipment impairment and loss of performance. In the Marine Renewable Energy (MRE) and other maritime sectors which operate at sea for long periods, an important aspect of biofouling is related to the type and frequency of maintenance.

Methods:This study investigated important parameters of macrofouling (for example composition, including the presence of non-indigenous species, thickness, and weight) from communities growing on small-scale wave energy components in marine conditions. The trials were performed during short periods of submersion (one to eight weeks) in the seasons when the colonisation process should be most intensive (spring, summer, and autumn). Furthermore, the frictional resistance forces generated to scrape the biofouling from those artificial components were investigated.

Results:Overall, results show that while biofouling growth in early colonization stages might not present great detrimental effects to wave energy components, although marine corrosion and the settlement of non-indigenous species (NIS) should be factors of concern.

Conclusions:  It is suggested to perform biofouling-related maintenance activities after the peak of maximum growth and reproduction (during the warmer seasons in temperate to cold environments) to reduce the number and frequency of activities. NIS can be detected very early in the colonization process, highlighting the importance of biofouling monitoring and the implementation of biosecurity risk assessment plans early in the operational stage of MRE projects.
Language resources and tools for Livonian
Authors: Ernštreits Valts , Fišel Mark , Rikters Matīss , Tomingas Marili , Tuisk Tuuli
Published: September 2022

This article describes linguistic collections of Livonian, development of digital resources, and their usage. The main motivation is to ensure the accessibility of Livonian intangible cultural heritage and linguistic materials for the Livonian and research communities as well as using digital technologies for the purpose of ensuring accessibility and making creation of resources more efficient. This paper also discusses digital technologies and tools needed by the Livonian community and researchers as well as challenges deriving from work with limited resources. A separate section discusses possibilities for adopting language technologies for low-resource languages based on the experiment of building a machine translation module for Livonian.

Kokkuvõte. Valts Ernštreits, Mark Fišel, Matīss Rikters, Marili Tomingas, Tuuli Tuisk: Keeleressursid ja -vahendid liivi keele jaoks. Käesolev artikkel annab ülevaate liivi keelekogudest, digitaalsete ressursside arendamisest liivi keele jaoks ja nende kasutamisest, et tagada liivi vaimse kultuuripärandi ja keeleliste materjalide kättesaadavus nii liivi kogukonnale kui ka laiemale teadlaskonnale. Samuti on digitehnoloogia kasutamise eesmärgiks tagada parem ligipääs allikatele ning muuta liivi keele jaoks vajalike ressursside loomine tõhusamaks. Artiklis käsitletakse liivlaste kogukonnale ja teadlastele vajalikke digitehnoloogiaid ja vahendeid ning piiratud ressurssidega tööst tulenevaid väljakutseid. Eraldi alapeatükis analüüsitakse vähese ressursiga keelte keeletehnoloogia kasutuselevõttu, tuginedes liivi masintõlke katsetamisele.

Kubbõvõttõks. Valts Ernštreits, Mark Fišel, Matīss Rikters, Marili Tomingas, Tuuli Tuisk: Resursõd ja vaindõkst līvõ kīel pierāst. Kēra tǟmikšõb iļvaņtlimiz iļ līvõ kīel kubūd, līvõ kīel pierāst lūodõd digitālizt resursõd, nänt kazāntimiz ja kȭlbatimiz, višīņtõs līvõd vaimlizt kultūr pierāndõkst ja tarmõs võimiži päzzõ kīel materjalõd jūrõ līvliztõn eņtšõdõn ja ka tuņšlijiztõn. Digitālizt tehnolōgijd kazāntimiz merk um ka parāntõ ovātõd kȭlbatimiz võimiži ja tīedõ līvõ kīel pierāst vajāglizt resursõd lūomiz jo kievāmõks. Kēra nīžõb iļ digitālizt tehnologijd ja vaindõkst, mis ātõ tārpalizt līvõd ja tuņšlijizt pierāst, ja iļ problēmõd, mis suggõbõd piškīzt resursõdõks jelāmizõst. Īžki kabāl um pivāstõd kīel tehnologijd kȭlbatimizõn piškīzt resursõdõks kīeld pierāst – sīesõ alīzõks um kȭlbatõd līvõ kīel mašīntulkõm lūomiz nägțõb.
Notes on an obsolete tensed negative pronoun construction in Livonian
Authors: Blokland Rogier
Published: September 2022

In language contact situations indefinite pronouns are susceptible to borrowing and/or calquing, and Livonian, which has been under strong influence of Latvian, is no exception. The negative prefixoid äb, originally the third person singular of the negative auxiliary äb, and calqued on Latvian ne- NEG, has been used to form nouns (e.g., äbkūlzit NEG.obedience ‘disobedience’), adjectives (e.g., äbjõvā NEG.good ‘bad’) and adverbs (e.g., äbknaššõ NEG.nicely ‘nastily’), but in a number of 19th century sources one also finds indefinite pronouns with this same negative prefixoid, e.g., a̤b midāgid ‘nothing’. However, due to the synchronous identity of äb as a tensed negative auxiliary (present tense: äb, past tense: iz), in past tense clauses the negative prefixoid of indefinite pronouns was then also inflected, leading to forms such as is midāgid. For a brief period in the 19th century Livonian therefore had a tensed negative pronominal construction.

Kokkuvõte. Rogier Blokland: Tähelepanekuid ajaliselt määratletud eitusvormi sisaldava vana asesõnakonstruktsiooni kohta liivi keeles. Keelekontaktisituatsioonis võidakse indefiniitseid asesõnu kergesti laenata ja/või tõlkida ning tugeva läti keele mõju all olnud liivi keel ei ole selles suhtes erand. Eitav prefiksoid äb, mis algselt on eituse ainsuse 3. pöörde abiverb, on tõlkelaen läti keelest: ne- NEG. Liivi äb-i abil moodustatakse nimisõnu (nt äbkūlzit NEG.sõnakuulelikkus ‘sõnakuulmatus’), omadussõnu (nt äbjõvā NEG.hea ‘halb’) ja määrsõnu (nt äbknaššõ NEG.ilusasti ‘inetult’), kuid mitmest 19. sajandi allikast on leida ka indefiniitseid asesõnu sama eitava prefiksoidiga, nt a̤b midāgid ‘ei midagi’. Kuna äb on samal ajal ka eituse ajaliselt määratletud abiverb (olevikus äb, minevikus iz), on mineviku ajavormis lausetes indefiniitse asesõna eitav prefiksoid olnud samuti muudetud mineviku ajale vastavaks: is midāgid. Seega esinesid liivi keeles 19. sajandil lühikest aega eituse ajaliselt määratletud pronoomenikonstruktsioonid.

Kubbõvõttõks. Rogier Blokland: Tǟdõlpanmizt iļ vanā azūmsõnā konstruktsij, mis sizāldõb āigas markīertõd kīeldõksformõ. Kīeld kubbõpūtimiz situātsijs äbpīldzizt azūmsõnād võibõd kievāmstiz sōdõ täpīņtõd ja/agā tulktõd ja nei se um ka līvõ kīels, mis um vȯnd viš lețkīel mȯj alā. Kīeldõks prefiksoid äb, mis amā ežmõks um vȯnd 3. pärsōn abverb īdlug kīeldõks form, um kalk lețkīelstõ: ne- NEG. Līvõ kīels sīe äb abkõks sōbõd lūodõd nimsõnād (nägțõbõks, äbkūlzit NEG.kūlzit), ummitsõnād (nägțõbõks, äbjõvā NEG.jõvā) ja vīțsõnād (nägțõbõks, äbknaššõ NEG.knaššõ). Setmiņst 19. āigastsadā ovātst ātõ lieudtõb ka äbpīldzizt azūmsõnād seļļizt eņtš prefiksoidõks, nägțõbõks, a̤b midāgid. Až äb sīel eņtš āigal um ka āigas markīertõd kīeldõks abverb (paldīņizāigas äb, lǟndzāigas iz), siz lǟndzāigas äbpīldziz azumsõnā kīeldõks prefiksoid kītõmis um vȯnd neiīž ka lǟndzāiga vorms: is midāgid. Nei siz 19. āigastsadās līvõ kīels lītizt aigõ ātõ vȯnnõd āigas markīertõd azūmsõnā kīeldõks konstruktsijd.
Livonian polar questions in their areal context
Authors: Norvik Miina , Metslang Helle , Pajusalu Karl , Saar Eva
Published: September 2022

This paper analyses strategies for forming polar questions and their historical sources in the two main varieties of Livonian – Courland Livonian and Salaca Livonian. The results reveal that the main means for marking polar questions in both varieties are sentence-initial particles. Their usage is compared to the means found in other varieties spoken in the Central Baltic area. This micro-areal comparison offers an in-depth analysis of the main patterns in the area, including their developmental paths. It appears that on several occasions, Livonian, Latvian, Latgalian, and Leivu South Estonian (spoken in Latvia) pattern together as opposed to the Estonian and South Estonian varieties (spoken in Estonia) and Lutsi and Kraasna South Estonian (spoken, respectively, in southeastern Latvia and the southern Pskov region in Russia). The data originate from various sources and different times, and were obtained by using both manual and automated methods; the analyses are qualitative.

Kokkuvõte. Miina Norvik, Helle Metslang, Karl Pajusalu, Eva Saar: Liivi keele üldküsimused areaalsel taustal. Artiklis analüüsitakse üldküsimuse vormistamise strateegiaid ning nende kujunemise allikaid kahes liivi keele põhikujus – Kuramaa liivi keeles ja Salatsi liivi keeles. Tulemused näitavad, et mõlemas on üldküsimusi moodustatud peamiselt lausealguliste partiklitega. Liivi keele üldküsimuste struktuuri võrreldakse areaalselt lähedaste keelte ja murrete moodustusviisidega. Selline mikroareaalne võrdlus võimaldab sügavuti analüüsida Balti areaalis leiduvaid põhilisi üldküsimuste vormimalle ning nende arenguteid. Artiklist ilmneb, et mitmel juhul osutuvad sarnaseks liivi, läti, latgali ja lõunaeesti leivu keelesaare üldküsimuste moodustusviisid, erinedes eesti keele, lõunaeesti murdekujude ning lõunaeesti lutsi ja kraasna keelesaare üldküsimuse moodustusest. Andmestik on kogutud mitmesugustest eri aegade allikatest ning seda on analüüsitud kvalitatiivselt.

Kubbõvõttõks. Miina Norvik, Helle Metslang, Karl Pajusalu, Eva Saar. Līvõ kīel iļammizt kizzimizt areāl kontekstõs. Kēras sōbõd vaņtõltõd amnämniz kizzimiz lūomiz stratēgijd ja nänt ovātõd kōds līvõ kīel vīțs – Kurmō līvõ kīels ja Salāts līvõ kīels. Tuņšlimi nägțõb, ku mȯlmis sōbõd kȭlbatõd partikõld, mis irdistiz ātõ lieudtõb kītõm īrgandõksõs. Kēra ītlõb līvõ kīel amnämnizt kizzimizt struktūrõ seļļizt īž struktūrõdõks munt ležgõlizt kēļši ja kīelmūrdis. Seļļi ītlimi äbțõb tuņšlõ amā sagdidi amnämnizt kizzimizt formõd modelidi ja nänt suggimizt Vāldamier areāls. Nei īž tuņšlimi nägțõb, ku amnämnizt kizzimizt struktūr pierrõ līvõ kēļ, lețkēļ, ladgal kēļ ja jedālēsti leivu kīelkōla ātõ jõvāgid ītizt – nēši kēļši struktūrõd ātõ mõitizt äbku ēsti kīels, jedālēsti kīelmūrdis, jedālēsti Lutsi ja kraasna kīelkōlis lieudtõb. Tieutõd tuņšlimiz pierāst ātõ kubbõ pandõd īžkižist ovātist ja tuņšlimiz pierāst sōbõd kȭlbatõd kvantitatīvizt metōdõd.
A century of Livonian studies at the University of Tartu
Authors: Tuisk Tuuli , Pajusalu Karl
Published: September 2022

The significance of the Livonian language and culture to Estonians is greater than mere historical closeness. The discipline of Livonian studies has been a part of Estonian national self-definition. The current article provides an overview of Livonian research and instruction since 1919 when the University of Tartu became the national university of Estonia. A consistent focus on Livonian language and culture during the last hundred years has been a good example of the Estonian national university’s broader mission, where national and international dimensions interweave in many ways. The University of Tartu is the only institution in Estonia where the Livonian language has been approached in such a multifaceted and in-depth manner, and has been taught, researched, and popularised.

Kokkuvõte. Tuuli Tuisk, Karl Pajusalu: Sajand liivi uuringuid Tartu Ülikoolis. Liivi keele ja kultuuri tähendus eestlastele on suurem kui pelgalt ajalooline lähedus. Liivi uuringud on olnud osa Eesti rahvuslikust enesemääratlusest. Käesolev artikkel esitab ülevaate liivi keele uurimisest ja õpetamisest Tartu Ülikoolis alates aastast 1919, kui sellest ülikoolist sai Eesti rahvusülikool. Järjepidev liivi keele ja kultuuriga tegelemine viimase saja aasta jooksul on hea näide Eesti rahvusülikooli laiemast missioonist, kus rahvuslik ja rahvusvaheline mõõde põimuvad mitmel moel. Tartu Ülikool on ainuke asutus Eestis, kus liivi keelega on nii mitmekülgselt ja pikaaegselt tegeldud – õpetatud, uuritud ja tutvustatud.

Kubbõvõttõks. Tuuli Tuisk, Karl Pajusalu: Līvõd tuņšlimizt āigastsadā Tartu Iļīzskūols. Līvõ kīel ja kultūr tǟntõks ēstlizt pierāst um jo sūr äb ku set istōrili ležglit. Līvõd tuņšlimi um vȯnd ikš jag Ēstimō eņtšmēļitõst. Kēra tǟmikšõb iļvaņtlõks iļ līvõ kīel tuņšlimiz ja opātimiz Tartu Iļīzskūols 1919. āigastõst, ku Tartu Iļīzskūolst tuļ Ēsti rov iļļiskūol, tämpiz sōņõ. Līvõ kīelkõks ja kultūrõks jelāmi perīz sadā āigast āigal um jõvā nägțõb Ēstimō rov iļīzskūol jo laigāst missijõst, missõst um nǟdõb, kui īdtuoizõks sieggõbõd rovvi ja rovvõdvaili. Tartu Iļļiskūol um āinagi optõbkūož Ēstimōl, kus līvõ kēļ um vȯnd nei sūr ov sizāl kōgiņ aigõ – siedā um opātõd ja tuņšõltõd, sīestõ um rõkāndtõd.
Non-pharmacological Therapy in Fibromyalgia
Authors: Rozenbajgier Martyna , Wójcik-Grudzień Justyna , Pawłowska Paulina , Ozga-Stachurska Alicja
Published: September 2022

Fibromyalgia (FM) is a syndrome manifested by chronic, generalized muscle and joint pain and symptoms such as sleep problems, mental disorders, mainly depression, which significantly reduces the patients' quality of life.The etiology, pathogenesis, and pathomechanism of symptoms in FM are still not fully understood, which makes the therapeutic options unsatisfactory. Treatment is mainly based on relieving the symptoms of the disease and is based on both pharmacological and non-pharmacological treatments. It seems that the best results are achieved by a combination of cooperation between a rheumatologist, psychiatrist, psychologist and phosiotherapist.

The aim of the study is to present the current state of knowledge about the possibilities of non-pharmacological treatment in people with fibromyalgia

Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords: fibromyalgia, chronic pain, non-pharmacological therapy in fibromyalgia
Insulinoma - review of characteristics, diagnosis and treatment
Authors: Sapuła Klaudia , Remjasz Klaudia , Siedlecki Wojciech , Fabiś Mateusz , Kuchnicka Julia , Aleksandrowicz Jakub , Zielińska Martyna
Published: September 2022

Introduction and purpose:

Insulinoma is one of a group of pancreatic neuroendocrine neoplasms (NENs). This tumor has its origin in the β cells of the pancreatic islets, which are responsible for the production of insulin. Excessive amounts of this hormone in the body manifest hypoglycemic neuroglycopenic and sympathetic-overstimulation symptoms. The purpose of this review is to analyze information on the characteristics, diagnosis and treatment of patients with insulinoma. 

Material and methods:

This review was based on available data collected in the PubMed database and published between 2017 and 2022. The study was conducted by reviewing keywords as follows: "insulinoma," "NEN," "diagnosis," and "treatment."

Results:

The diagnosis of insulinoma consists of a typical clinical presentation, biochemical test results indicating hyperinsulinemic hypoglycemia, and presence of a tumor. The treatment targets solutions leading to a complete recovery, usually performing open surgery involving enucleation of the tumor.

Conclusions:

Despite the characteristic clinical picture, insulinoma is still often a diagnostic problem. It is necessary to work towards improving diagnostic methods and conduct further research into the most effective methods of treating insulinoma.
Emine Işınsu’nun Hikâyelerinde Feminizm
Authors: DİNÇER YİĞİT Elif
Published: September 2022

Kadın, Batılılaşma sürecinden beri çağdaşlaşmanın simgelerinden biridir. Kadınlar yasalar üzerinde erkeklerle eşit haklara sahip olsalar da ataerkil yaşam tarzının getirdiği alışkanlıkların kısa zamanda terk edilememesi nedeniyle bu eşitliğin uygulanabilirliğini yaşamda görmek mümkün olmamıştır. Demokrasi kavramı, II. Meşrutiyet’ten sonra bir bakıma feminizm hareketiyle birleşir ve demokrasinin yaşamasını sağlayacak şahsiyetleri yetiştirecek kadın özlemi başlar. Simone De Beauvoir’rın öncülüğünde başlayan ve “İkinci Dalga Kadın Hareketi” olarak adlandırılan feminist hareket seksenli yıllarda Türkiye’yi de etkiler. Toplumsal cinsiyete dair kadının varoluş problemlerinin tartışıldığı, kadın olmanın ve kadınsal soruların ele alındığı bu dönemde kadın artık dinleyen konumundan çıkar ve konuşan, tartışan ve kendi kararlarını kendisi alan bir konuma gelir. Ülkemizde de yasal haklarını kullanamayan, baskı ve şiddet gören kadınlar -kısmen- ideolojik maksatlarla da olsa yakın dönem romancıları tarafından işlenir. Bu yazarlardan birisi de Emine Işınsu’dur. Özellikle de hikâyelerinde bu konuya eğilen sanatçının bu hikâyeleri, seksen sonrasında edebiyatımızda bir kırılma yaşayan kadın sorununun birer örneği olması bakımından önemlidir. Çalışmamızda, kadın sorunlarına eğilen bu hikâyelerdeki feminist unsurları tespit etmeyi ve bu unsurların nasıl ve hangi amaçla kullanıldığını belirlemeyi amaçlamaktayız.
Hand-arm vibration while operating a side brush cutter with three cutting implements in two crops
Authors: Cella Mateus Cassol , Werner Valmir , Brandelero Catize , Bertollo Gilvan Moisés , Silva Edvaldo Faour Coutinho da , Schlosser José Fernando , Martin Thomas Newton
Published: September 2022

The use of side brushcutters exposes users to vibration and noise, which can cause damage to the operator, as they act as a stressor agent. Excessive vibration is responsible for countless disorders, including Raynaud’s syndrome. This study aimed to assess the effect of the vibrations of a side brush cutter on the human body. A side brush cutter was used with three cutting implements (double blade, triple blade and double nylon thread) applied to two crops (wheat and ryegrass). The vibration was measured through a three-dimensional accelerometer placed on the handgrips of the brush cutter, in compliance with the provisions of the ISO 5349-1 Standard. The analyzed variables were submitted to the Shapiro-Wilk and Bartlett tests. Due to the abnormality, the data were transformed by the Neperian logarithm and submitted to analysis of variance, and the means were compared by the Tukey test at 5% probability. As a result, the orthogonal y-axis presented a higher vibration level; the three-point blade showed the lowest vibration level compared to the other cutting implements for both crops; these vibration levels did not exceed the NHO10 recommendation. Hence, using the appropriate attachment for each operation may reduce the harm caused by vibration to the operator’s body.
Scalable optical-to-terahertz converter with a prism-coupled plane-parallel lithium niobate plate
Authors: Bodrov S. B. , Abramovsky N. A. , Burova E. A. , Stepanov A. N. , Bakunov M. I.
Published: September 2022

A nonlinear optical converter of femtosecond laser pulses to terahertz radiation, which combines the tilted-pulse-front pumping and prism coupling techniques, is proposed and experimentally tested. In contrast to the conventional tilted-pulse-front scheme with a prism-shaped LiNbO3 crystal, the converter consists of a plane-parallel LiNbO3 plate sandwiched between two dielectric prisms. One prism is used to couple the pump beam into the LiNbO3 plate, another prism couples the generated terahertz radiation out of the plate. The proposed scheme enables scaling to large-diameter LiNbO3 wafers and large-aperture high-energy pump laser beams resulting in generation of strong terahertz fields. In a proof-of-principle experiment with a 1-mm thick, small size (1 × 2 cm2) LiNbO3 plate pumped by a mJ-class laser, the conversion efficiency comparable to that of the conventional scheme (∼0.1%) was demonstrated.
The moon, the play and the end of history: A study of lunar temporality in Cyberpunk 2077
Authors: Kaniewska Joanna
Published: September 2022

This article aims to analyse the representation of the moon in the open-world action RPG Cyberpunk 2077, released by CD Projekt Red in 2020, and its influence on a experience of time during the play. A close reading of CD Projekt’s title suggests a non-mimetic, cinematic and subjective approach to time in the game. Additionally, in Night City, the moon does not change its appearance and remains in its full phase almost until the end of the game. It serves as a bridge between the pre-designed narrative and the ludic interactions with the open world, creating an experience unique to the medium of video games. It signalizes that the player and their avatar V have entered the diachronic, atemporal space. At the same time, the lunar temporality can be read as an emanation of cyberpunk’s frozenness-in-time and its embrace of the neo-liberal version of the end of history.
Multiverse ethnography: A qualitative method for gaming and technology use research
Authors: Karhulahti Veli-Matti , Kauraoja Valtteri , Ouninkorpi Olli , Perttu Soli , Perälä Jussi , Toivanen Vilma , Siutila Miia
Published: September 2022

This article introduces multiverse ethnography as a systematic team-based qualitative method for studying the mechanical, structural and experiential properties of video games and other technological artefacts. Instead of applying the ethnographic method to produce a single in-depth account, multiverse ethnography includes multiple researchers carrying out coordinated synergetic ethnographic work on the same research object, thus producing a multiverse of interpretations and perspectives. To test the method, 41 scholars carried out a multiverse ethnography on two video games, Cyberpunk 2077 and Among Us. Explorative thematic findings regarding both titles are reported and methodological implications of multiverse ethnography are discussed.
La escuela: lugar de significado y compromiso
Authors: Ibáñez Ayuso María José , Limón Mendizabal M.ª Rosario , Ruíz-Alberdí Cristina María
Published: September 2022

Distintos fenómenos sociales relativos a la infancia y la juventud parecen cuestionar la capacidad de la escuela para crear significados comunes y garantizar la preparación de personas capaces de vivir en democracia. El objetivo de este artículo es demostrar que la transmisión cultural que se produce en el seno de la institución escolar es la base de los procesos de humanización que suceden en la escuela al fomentar en los alumnos la construcción de una identidad personal sólida, capaz de encontrar sentido a la propia vida y de comprometerse con la realidad social, cultural, política y económica de la que forma parte. Para ello, se exponen, en primer lugar, tres presiones a las que se encuentra sometida hoy la escuela para que, en aras del progreso, renuncie a la misión que le es propia y sucumba a la tentación de educar en el vacío cultural. A continuación, se defiende el valor de la escuela como generadora, a través de la cultura, de una realidad significativa, que permite hallar sentido a la propia vida y capacita para el encuentro y compromiso con los otros a través de la creación de significados comunes. Por último, se muestra cómo la escuela contribuye a la formación de tres dimensiones (narración, inteligibilidad y responsabilidad) necesarias para vivir en democracia. Como conclusión, se reclama la importancia de la reflexión teleológica como guía de la actuación educativa para resistir a una agenda que pone en riesgo la auténtica educación en libertad: la de la libertad que trasciende a la mera apetencia para comprometerse con el otro.
La formación en centro del profesorado no universitario: modalidad fundamental en su formación permanente
Authors: Alonso Briales Mariana , Vera Vila Julio
Published: September 2022

La formación permanente supone un proceso de aprendizaje que se desarrolla a lo largo de toda la trayectoria vital del docente, dando respuesta a las necesidades y problemas reales que el profesorado tiene en su práctica para desarrollar sus propias competencias profesionales en un contexto de cambio continuo. Una de las modalidades fundamentales de formación permanente del profesorado no universitario es la Formación en Centro, dado que parte, se ajusta y revierte en el propio contexto, facilitando de esta manera el análisis, la reflexión y la mejora de la práctica docente.
En este trabajo se presenta una investigación de corte cualitativo, centrada en cinco estudios de casos, cuatro centros educativos públicos de Infantil y Primaria y el Servicio de Atención Educativa Hospitalaria y Domiciliaria de Málaga, que se implican en el desarrollo de una Formación en Centro como iniciativa para dar respuesta a sus necesidades formativas, a los problemas que el profesorado encuentra en su práctica.
Como demuestran los resultados, estos Proyectos de Formación en Centro, orientados hacia la mejora personal, profesional e institucional, tienen un enorme potencial para la formación permanente y el desarrollo profesional del profesorado. Son proyectos con gran capacidad para adaptarse al contexto y a las necesidades reales del profesorado, que ayudan a prevenir el malestar docente, a evitar la inhibición y la rutina, y a incrementar el interés por la búsqueda de nuevas propuestas educativas. Por tanto, concluimos que la Formación en Centro es valorada como una modalidad prioritaria dentro de los planes de formación permanente del profesorado en Andalucía, puesto que considera al centro educativo como el foco de formación y la unidad básica de cambio e innovación educativa. Además, favorece espacios de reflexión y participación, propuestas de cambio y de trabajo en equipo como desarrollo fundamental de la institución educativa y del profesorado.
„Én élni akarok mindenáron!” Az ellenállás és együttműködés lehetőségei két magyar holokausztnarratívában
Authors: Kérchy Anna
Published: September 2022

A két vizsgált szöveg a Holokauszt áldozatainak és túlélőinek állít emléket a fikciót és a realitást különböző mértékben elegyítő, töredezett vagy befejezetlen női fejlődésregényt idéző traumanarratívákban. Az Akik maradtak című filmadaptáció nyomán közismertté vált Férfiidők lányregénye a pszichológus F. Várkonyi Zsuzsa tollából két, a háborúban súlyos lelki sérüléseket szerzett, családját vesztett ember különleges barátságáról szól. A depressziós elfojtásban élő, középkorú nőgyógyász és az elárvult, anorexiás, szeretetéhes, rebellis kamaszlány egymásba kapaszkodásának története. Zsolt Ágnes eredetileg Éva lányom címmel megjelent Piros bicikli című könyvét a magyar Anne Frank naplójaként tartják számon. Az auschwitzi koncentrációs táborban meggyilkolt 13 éves Heyman Éva – édesanyja által szöveggondozott (esetleg általa is írt) – rövidke naplója korkép egy zsidó kislány mindennapjairól a nácik uralta Nagyváradon. A két szöveg egymás mellé állítva izgalmas párhuzamot rajzol.: Az egyik a trauma utótörténetére, a másik az előzményeire koncentrál; az egyik sikeresnek tűnő, a másik kudarcba fulladt gyászfeldolgozás produktuma (Zsolt Ágnes a könyv megjelenése után öngyilkos lett); az egyikben a szépirodalmi fikció, a másikban a (ál)dokumentarista realizmus felé mozdul el a hangsúly. Azonban mindkét szöveg az emlékezetkultúra formációk során sokáig tendenciózusan háttérbe szorult női perspektívát helyezi előtérbe, s ilyen értelemben ellen-diszkurzusként olvasható. A történelmi események mintegy a háttérben zajlanak, a tizenéves lányok meghatározó testtapasztalatai mögött. Közös pont a két könyvben az ellenállás és az együttműködés lehetőségeinek fontolóra vétele, a túlélés stratégiáinak morális mérlegelése. A két szöveg dilemmája, hogy az életben maradáshoz elkerülhetetlen-e az elnyomó rendszer kiszolgálása, vagy lehet-e a gyöngéd törődés, a Carol Gilligani „gondoskodás etika” önmagaságunk és közösségi identitásunk megőrzésének záloga.
Populáris kultúra és kulturális állampolgárság
Authors: Strickland-Pajtók Ágnes
Published: September 2022

A kutatás fő célja annak föltárása, hogy a populáris kultúra termékei ösztönözhetik-e közönségüket arra, hogy politikai, társadalmi kérdésekben akár önkéntelenül is állást foglaljanak.  Joke Hermes (2005) nyomán megfogalmazva, azt járja körül, hogy ezek a médiatermékek elősegíthetik-e a domináns hatalmi rendszerek megkérdőjelezését. A  kérdést A szolgálólány meséje című regény legújabb televíziós adaptációjának recepcióján keresztül kívánom megvizsgálni. A huszonkét, sorozatot néző nővel folytatott interjú elemzésének elsődleges célja annak bemutatása, hogy a befogadók hogyan viszonyulnak a sorozat szereplőihez és a cselekményéhez, illetve annak vizsgálata, hogy a sorozat interpretálása történhet-e a jelen politikai, kulturális kontextusának értelmező horizontja felől, és ha igen, hogyan fogalmazódnak meg azok a gondolatok, melyek nem csupán a sorozatra reflektálnak, de a néző saját jelenéhez fűződő viszonyáról is árulkodnak. A végső cél a válaszokból körvonalazódó kulturális állampolgárság alaposabb megértése.
Az ellenállás és az együttműködés retorikai megoldásai Lou Andreas-Salomé nőképében
Authors: Kegyes Erika
Published: September 2022

Lou Andreas-Salomé megítélése saját korában és ma is ambivalens. A kor nőmozgalmi teoretikusai nem fogadták be soraik közé, s korának számos nagy alakjával folytatott vitát a nőkép újragondolásáról. Később egyesek korunk feminizmusának előfutárának tartják, megint mások pedig antifeministát láttak benne. Salomé ambivalens megítélése valószínűleg annak is köszönhető, hogy irodalmi és teoretikus írásaiban is nehéz nyelvi képekkel dolgozott. Egyrészt a pszichoanalitikusként magával hozott képek tovább fejlesztésével, másrészt egy sajátosan felforgató, mindenekelőtt ironikus retorika kidolgozásával. Ennek a tanulmánynak a célja Salomé nyelvi képeinek elemzése és az írásait jellemző ellentmondásoknak a felvázolása. Salomé ugyan nem alkotott egységes elméletet a nő és férfi viszonyáról, de kísérletet tett arra, hogy az általa elgondolt nőkép-mintákat irodalmi alakjaiban megjelenítse. Lou Andreas-Salomé megítélése nem utolsósorban az irodalmi regiszter sajátosságai okán is ellentmondásos
Examination of masonry arch bridge’s life-cycle assessment under far-fault earthquakes
Authors: Lakusic Stjepan
Published: September 2022

The goal of this study is to examine the historical masonry arch bridge’s static and dynamic behavior using far-field fault earthquakes. The first step is to build a finite element model with ANSYS and SAP2000. This is done to see if the greatest possible displacements, primary stresses, and elastic strains compare. From above, the belt’s upper side appears to be vital for damage. Furthermore, a historical masonry arch bridge’s life cycle assessment is also researched and observed, which results in increased stress and strain values for the bridge, causing its expected life span to be drastically reduced.
A SHORT MESSAGING SYSTEM (SMS) ALERT FOR IDENTIFYING VICTIM LOCATION USING SMARTWATCH TECHNOLOGY
Authors: Bello Ibrahim Alhaji , Suleiman Dr. Ibrahim , Bello Abdulazeez Muhammad , Ibrahim Shahidu , Karatu Esther Haruna
Published: September 2022

The incidence of kidnapping peoples in Nigeria has taken an alarming dimension for reasons not well addressed by successive governments in Nigeria. This unlawful act has increase despite the various legislations prohibiting kidnapping both the international level and at the three tiers levels of government. The law against kidnapping has been passed almost a decade since 2013 by the federal government of Nigeria with some states in the country domesticating law from 2017-2021. The purpose of this paper is to design a software program that uses a smartwatch and is dubbed as blower. It can help the users (victim) to alert the security personnelâ€™s or relatives for help. When the report button on the smartwatch is clicked, the geolocation and the SMS application interface(API) are triggered, and SMS will generate with details of the current coordinates of the device location and sent to a predefined number. This message is sent continuously whenever the location changes. Is an innovative software suite (Web, Mobile, API, and Database) that can be used to help the victim, in curbing kidnapping issues in our society.
Como os Produtos MODIS têm sido Utilizados para Análise dos Parâmetros Biofísicos em Regiões Semiáridas? Uma Revisão Bibliométrica e de Literatura
Authors: Bezerra Alan Cézar , Moura Geber Barbosa de Albuquerque , Lopes Pabrício Marcos Oliveira , Ribeiro Eberson Pessoa , Galvíncio Josiclêda Domiciano , Ferraz Edimir Xavier
Published: September 2022

O sensoriamento remoto é uma tecnologia que permite o monitoramento do ambiente com baixo custo e alta periodicidade, sendo os produtos do sensor Moderate Resolution Imaging Spectroradiometer (MODIS) um dos mais utilizados. Assim, busca-se apresentar as aplicações do sensor MODIS e os padrões sazonais das formas de uso e cobertura da terra na análise com parâmetros biofísicos em regiões de semiárido, sendo dividida em três seções: a primeira sobre o sensor MODIS, explicando suas características; a segunda é uma revisão bibliométrica da aplicação de parâmetros biofísicos obtidos com MODIS em ambiente semiárido; por fim, na terceira sessão, contextualiza os métodos de detecção das mudanças de uso e cobertura da terra. Para isso, a base de dados utilizada foi a Web of Sciente (WOS), que possui acesso a base de dados como ProQuest, Scopus e Wiley. O período considerado foi de 2000 até 2019 e as palavras chaves pesquisadas foram: MODIS, Semiárido e Biofísico. Com esta revisão, concluiu-se que o sensor MODIS pode oferecer relevantes produtos para o monitoramento ambiental, destacando-se o MOD13, MYD13, MOD09, MOD11, MCD 15, MCD43, MCDB3, MOD16 e MOD17. Os estudos que buscam verificar os impactos das mudanças climáticas necessitam ser cautelosos nas análises dos resultados obtidos, em razão da contaminação dos produtos por fatores atmosféricos. Ademais, para avaliar as mudanças ocorridas em uma região, alguns estudos priorizam o uso da estatística descritiva das imagens e as perspectivas futuras deverão considerar o uso de análise de tendências temporais a uma coleção de produtos do sensoriamento remoto.
The Estimation of Water Quality Parameters in Lentic Environments Through Remote Sensing Technologies: a Review of the Past Two Decades
Authors: Pizani Fernanda , Maillard Philippe , Amorim Camila Costa
Published: September 2022

The use of remote sensing technology applied to measure the quality of continental waters has grown exponentially since the turn of the century. Using different sensors on board satellites or airborne platforms, the estimation of water quality parameters has been carried out through both empirical and analytical approaches. This work aims to review the specific scientific production of the last two decades to assess how the evolution of the sensors and platforms have affected the potential and the limitations of remote sensing technologies to estimate water quality parameters in lakes and reservoirs. The study also focuses on the accuracy of remote sensing techniques for the major optically active parameters: chlorophyll-a and phycocyanin, Secchi disk depth and turbidity. The article is subdivided by sections dedicated to each of these parameters. A review of remote sensing platforms and sensors precedes the parameters sections. The past 20 years have brought a large body of articles on how remote sensing data can be used to estimate these parameters. Empirical methods dominate overwhelmingly with a four to one proportion over analytical approaches. Environmental factors such as season, complexity of water and concentration loads appear to exert a strong control over the quality of the results. Recent platforms and sensors have brought noticeable improvements over results achieved in this period.
El encuentro como dimensión de las culturas y el camino hacia la paz
Authors: Sosa Arturo
Published: September 2022

La injusticia estructural que caracteriza las relaciones sociopolíticas actuales es una pesada herencia que la época histórica que acaba de terminar deja a la nueva que comienza. En efecto, en esta época cambiante asistimos a situaciones, como la pandemia del Covid-19, que al afectar a toda la humanidad revelan claramente el alcance y la profundidad de esta injusticia estructural. Las brechas sociales, la pobreza, la migración forzada y otras calamidades siguen creciendo. Parece imposible detener la degradación medioambiental causada por los fastuosos modelos de producción y estilos de vida que ha generado el capitalismo de consumo globalizado. Los conflictos armados continúan y aumentan, incluso en lugares donde parecía que se habían encontrado alternativas para resolver los conflictos. La política mundial ha demostrado ser inmadura, incapaz de gobernar el mundo en el interés común de la humanidad. Ante este panorama, necesitamos del encuentro intercultural como camino hacia la paz.