bluuebunny/crossref_metadata_2025 huggingface dataset:
Hypoxic Glioma Stem Cell–Derived Exosomes Containing Linc01060 Promote Progression of Glioma by Regulating the MZF1/c-Myc/HIF1α Axis
Authors: Li Junjun , Liao Tingting , Liu Hongya , Yuan Hongliang , Ouyang Taohui , Wang Jiajing , Chai Songshan , Li Jinsong , Chen Jingchao , Li Xiang , Zhao Hongyang , Xiong Nanxiang
Published: November 2020

Glioma stem cells (GSC) are a subpopulation of tumor cells with special abilities to proliferate and differentiate in gliomas. They are one of the main causes of tumor recurrence, especially under hypoxic conditions. Although long noncoding RNAs (lncRNA) are known to be involved in numerous biological processes and are implied in the occurrence of certain diseases, their role in tumor development and progression remains poorly understood. Here we explored the mechanisms by which lncRNA derived from hypoxic GSCs (H-GSC) cause glioma progression. Isolation and identification of the Linc01060 gene, the exosomes containing them, and the proteins from tumor cells regulating the gene allowed for studying the effects of Linc01060 on proliferation and glycometabolism. H-GSC exerted their effects by transferring exosomes to glioma cells, resulting in a significant increase in Linc01060 levels. Mechanistically, Linc01060 directly interacted with the transcription factor myeloid zinc finger 1 (MZF1) and enhanced its stability. Linc01060 facilitated nuclear translocation of MZF1 and promoted MZF1-mediated c-Myc transcriptional activities. In addition, c-Myc enhanced the accumulation of the hypoxia-inducible factor-1 alpha (HIF1α) at the posttranscriptional level. HIF1α bound the hormone response elements of the Linc01060 promoter, upregulating the transcription of Linc01060 gene. Clinically, Linc01060 was upregulated in glioma and was significantly correlated with tumor grade and poor clinical prognosis. Overall, these data show that secretion of Linc01060-containing exosomes from H-GSCs activates prooncogenic signaling pathways in glioma cells to promote disease progression.

Significance:

These findings suggest that inhibition of Linc01060-containing exosomes or targeting the Linc01060/MZF1/c-Myc/HIF1α axis may be an effective therapeutic strategy in glioma.
BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma
Authors: Busacca Sara , O'Regan Laura , Singh Anita , Sharkey Annabel J. , Dawson Alan G. , Dzialo Joanna , Parsons Aimee , Kumar Neelam , Schunselaar Laurel M. , Guppy Naomi , Nakas Apostolos , Sheaff Michael , Mansfield Aaron S. , Janes Sam M. , Baas Paul , Fry Andrew M. , Fennell Dean A.
Published: November 2020

Mesothelioma is a universally lethal cancer lacking effective therapy. The spindle poison vinorelbine exhibits clinical activity in the relapsed setting, and in preclinical models requires BRCA1 to initiate apoptosis. However, the mechanisms underlying this regulation and the clinical implications have not been explored. Here, we show that BRCA1 silencing abrogated vinorelbine-induced cell-cycle arrest, recruitment of BUBR1 to kinetochores, and apoptosis. BRCA1 silencing led to codepletion of MAD2L1 at the mRNA and protein levels consistent with its status as a transcriptional target of BRCA1. Silencing of MAD2L1 phenocopied BRCA1 and was sufficient to confer resistance to vinorelbine. This was recapitulated in cell lines selected for resistance to vinorelbine, which acquired loss of both BRCA1 and MAD2L1 expression. Following ex vivo vinorelbine in 20 primary tumor explants, apoptotic response rate was 59% in BRCA1/MAD2L1-positive explants compared with 0% in BRCA1/MAD2L1-negative explants. In 48 patients, BRCA1 and/or MAD2L1 loss of expression was not prognostic; however, in a subset of patients treated with vinorelbine, survival was shorter for patients lacking BRCA1/MAD2L1 expression compared with double-positive patients (5.9 vs. 36.7 months, P = 0.03). Our data implicate BRCA1/MAD2L1 loss as a putative predictive marker of resistance to vinorelbine in mesothelioma and warrant prospective clinical evaluation.
Developing a speaking handout for ESP students
Authors: Aflah Mita Nur , Rahmani Eka Fajar
Published: November 2020

This paper aims at encouraging medical students of Poltekkes Pontianak to speak in English by developing a speaking handout as one of the sources for their English subject. The handout is addressed to first semester students as an introduction of English. Speaking skill is chosen because the demands of professional medical workers who are competent in speaking English have increased. In the work-life, medical workers are required to be able to speak in English as an international media of communication for the proof of their professionalism. Therefore, the development of the handout is highly important. The data used to develop the handout is primarily the need analysis results of the previous research. The material development process employs two phases of ADDIE: Design phase and Development phase adapted from Branch (2009) with some pertinent modifications to the contexts and primary data. The complete handout as the final result contains the activities and tasks of speaking English with the clear user’s guides for its users.
Development of Problem-based Blended Learning (PB2L) model to increase pre-service primary teacher’s creative thinking skill
Authors: Wahyudi Wahyudi , Waluya Budi , Suyitno Hardi , Sutriyono Sutriyono , Anugraheni Indri
Published: November 2020

Problem-based learning is generally done with face-to-face interaction. This learning process, however, has not provided a lot of time for learners to find limitless and timeless information and learning resources. It still depends on the teacher as a source of information. Students are very dependent on the presence of lecturers during face-to-face interaction. This research aims to develop a Problem-based Blended Learning (PB2L) model to support student to improve their creative thinking skills. The method used in this research was RD with ASSURE development model. Product validation was done through an expert’s assessment by using the expert’s validation sheet. The practicality of the product is tested with limited trials with college lecturers and some students with questionnaires and interviews. Product effectiveness was seen by implementing limited development testing to a particular class with a one group pretest-posttest design and the result was analyzed by using a Paired-Samples T-Test. The result of this research is a Problem-based Blended Learning (PB2L) valid, practical and effectively improves students' creative thinking abilities. The effectiveness of the learning model was also proven on the basis of Paired-Samples T-Test of students’ pretest and posttest with sig. (2-tailed) 0.000. This learning gives students the opportunity to think systematically by beginning by criticizing the interesting contextual problems and ending with meaningful reflection with adequate learning resources both in face-to-face and online interaction.
A mathematical anxiety scale instrument for junior high school students
Authors: Anindyarini Rosyita , Supahar Supahar
Published: November 2020

Anxiety becomes one of the psychological symptoms that can appear in every student while solving mathematics problems. Anxiety cannot be denied to be one factor that affects students’ learning outcomes and interest in mathematics. Therefore, teachers should concern on this matter in order to decide the appropriate learning strategy. However, there is no instrument to measure the level of students’ anxiety towards mathematics, especially for junior high school students. For that reason, this research aims to: 1) design the construct of math anxiety scale instrument, 2) find out the validity of the instrument. This research used Research and Development method to develop and validate the product which is in the form of a questionnaire. The analysis techniques used V Aiken for content validity, EFA for construct validity, and Cronbach’s Alpha for the reliability. The results of this research showed that the instrument was valid and reliable because it met the criteria for validity and reliability. In conclusion, the instrument is valid to measure the junior high school students’ math anxiety level.
Implementation of chain story techniques to improve english speaking ability at imanuel YPK vocational high school, Sorong City
Authors: Uktolseja Lulu Jola , Gaspersz Sherly
Published: November 2020

The function of English as the international language that connects various countries with different languages makes English as an important communication tool to be learned and taught for students from various levels of education as the provision to face the current era of globalization. The chain story technique that implemented in this research, is a technique that is suitable to be used to teach students who have not dared to actively use English. This technique helps students of Imanuel YPK Vocational High School, Sorong City to work as a team and help each other to construct the sentence. This study was designed in the form of Classroom Action Research (CAR). The method of this research is a qualitative and quantitative method. The qualitative to explain the condition before and after the action. The quantitative to count the score of the students. As for the subject in this research is the Class X Automation and Office Management. This is done in order to obtain valid and reliable research data. Data collection techniques used were observation, test and interview. Results of the study showed that: (1) Based on the observation, the students are changed to be more brave and confident to speak English; (2) Based on the test, there is a very significant change towards the positive, when compared to the value of very good and good in cycle 1 which is 42% while in cycle 2 is 80%, so there is an increase of 38%; (3) Based on the interview, the students were happy and giving the good responses about the treatment and the progress they have done
Association between interprofessional collaboration readiness and clinical decision making ability of midwifery students
Authors: Hermasari Bulan Kakanita , Afifah Brian Sahar , Cahya Erindra Budi
Published: November 2020

Maternal mortality remains a major challenge to health system worldwide. This problem requires the attention of health practitioners and health professional educators including midwives. Effective clinical decision making is among the most important skills required by healthcare practitioners in the intra-profession and interprofessional context.  This study aims to explore the midwifery student's clinical decision-making ability and attitude toward interprofessional learning. This study  used quantitative design with cross-sectional approach. Subjects of research were 50 midwifery students. The instruments were The Readiness  for Interprofessional Learning Scale (RIPLS) questionnaire; and an assessment rubric of the obstetric case study. Most of the students are not ready to collaborate with other health professions (68%), and have low and moderate clinical decision-making abilities (98%). There is a significant positive correlation (p 0.05) between student readiness for interprofessional collaboration with clinical decision-making ability. This study emphasizes that the ability of a midwife in clinical decision making, especially in emergency cases, is related to their readiness or experience in collaborating with other health professionals.
Reading inequities by the economic status of Texas grade 3 english language learners: A Texas, multiyear analysis
Authors: Schleeter Gideon D , Slate John R. , Moore George W , Lunenburg Frederick C
Published: November 2020

Analyzed in this investigation were the current Texas state-mandated assessments in reading and the extent to which test scores differed among English Language Learners who were Not Poor (i.e., did not qualify for the reduced or free lunch program), English Language Learners who were Moderately Poor (i.e., qualified for the reduced lunch program), and English Language Learners who were Extremely Poor (i.e., qualified for the free lunch program). In all cases, reading achievement was lowest for English Language Learners who were Very Poor, followed by English Language Learners who were Moderately Poor. English Language Learners who were Not Poor had the highest reading performance in all four school years. Implications for policy and practice, as well as recommendations for future research, are provided.
Inculcating Islamic values contented in Qs. Luqman through english speaking materials
Authors: Anshari Muhammad Zuhri , Widyantoro Agus
Published: November 2020

Islamic junior high schools have more duties than the public schools. They have the duty of teaching Islamic values to their students because these schools are established based on Islamic teachings. Islamic values must be included in all aspects of the school program. The materials used for teaching the students should also contain Islamic values. Unfortunately, based on the writers’ observation, not all Islamic junior high schools integrate Islamic values in the materials taught to the students. This fact challenges the English teachers in Islamic schools to select and to consider the appropriate values, cultures, and ideologies in teaching and learning English process. As a result, this paper is based on a study conducted to develop materials which integrate Islamic values for teaching Speaking in a private junior high school in Yogyakarta. The study was aimed to reveal the students’ needs in relation to the integration of the Islamic values in the materials for teaching the speaking skill and to know the appropriateness of the materials. This is an R D study. To design the textbook the ADDIE Model was employed. To meet the textbook appropriateness, the designed textbook is analysed by conducting theoretical and empirical validation. The result of the study indicates that the designed materials are appropriate to be used in the Islamic schools.
Principals’ instructional time management and students’ academic performance in secondary schools in Ondo North senatorial district of Ondo State, Nigeria
Authors: Ayeni Adeolu Joshua
Published: November 2020

The persistent concern of stakeholders in the education sector over the dwindling academic performance of students in Nigerian secondary schools could be attributed to the perceived inadequacies in instructional time management. This study therefore investigated principals’ instructional time management strategies, teachers’ effectiveness in instructional tasks, and students’ academic performance in secondary schools in Ondo North Senatorial District of Ondo State, Nigeria. Descriptive design of the survey type was adopted. Multi-stage sampling technique was used to select 30 public secondary schools from three (3) Local Government Areas in the Northern Senatorial Districts of Ondo State. The sample comprised 600 teachers and 30 principals randomly selected for the study. Three (3) research questions were answered using frequency counts and percentage, while three (3) hypotheses were tested using Pearson Product Moment Correlation (PPMC) at 0.05 level of significance. Findings indicated a significant relationship between principals’ time management strategies and teachers’ instructional tasks performance (r-cal=0.622, p0.05), there was significant relationship between principals’ time management strategies and students’ academic performance (r-cal=0.702, p0.05), and significant relationship between teachers’ instructional tasks performance and students’ academic performance (r-cal=0.587, p0.05). The major constraints to instructional time were pressure of administrative duties and excess workload. Based on the findings, it was recommended that principals should step-up efforts at prioritizing administrative tasks, encouraging teamwork in instructional activities and delegating duties to the experienced teachers in the management cadre to reduce excess workload, and improve monitoring and evaluation of teachers’ instructional tasks performance for better academic performance of students in secondary schools.
Quality control measures and student output in University of Uyo and University of Calabar
Authors: Iroegbu Ekaette Emenike , Etudor-Eyo Eno
Published: November 2020

The study examines the nature of relationship between quality control measures and student output in University of Uyo and University of Calabar. Two research questions and two hypotheses guided the study. The correlational research design was used for the study. The population comprised 2,967 teaching staff and 11,635 students from University of Uyo and University of Calabar. Simple random sampling technique was used to select 642 teaching staff and 1,232 students from the sampled schools. Two instruments, one being researchers-developed instrument titled “Quality Control Questionnaire (QCQ)” and a documentary analysis checklist titled “Student Output Checklist (SOC)” were used for data collection. The instruments used for data collection were face validated by three experts. The reliability co-efficient of QCQ was determined using the Cronbach Alpha Analysis and a reliability index of 0.81 was obtained. The r-value of Pearson Product Moment Correlation (PPMC) coefficient was used to answer the research questions, while PPMC was used to test the null hypotheses at 0.05 level of significance. The findings of the study revealed that the quality control on student intake and student engagement significantly relates to student output in University of Uyo and University of Calabar. It was therefore concluded that the quality of student output in University of Uyo and University of Calabar is influenced by quality control variables. Based on the findings of this study, it is therefore recommended amongst others that, universities’ admission regulatory body should ensure that all prospective students vying for admission have good grades in their O’levels and Unified Tertiary Matriculation Examination (UTME). Furthermore, all candidates should also be admitted based on merit in order to ensure quality student output.
Self-regulation of primary education pre-service teachers
Authors: Sukowati Sukowati , Mustadi Ali , Putro Ahmad Agung Yuwono , Pradewi Gunarti Ika
Published: November 2020

Motivation for the achievements is urgently needed when attending a class. For renforcing the motivation can be obtained through self-regulation this research aimed to discover students’ self-regulation in a private university at Yogyakarta. This research used quantitative approach in the form of survey. The population in this research was all students in Primary school Teacher Education comprising 233 students. Whereas, there were 155 students as  the sample taken by using random sampling technique. Furthermore, students’ self-regulation was measured by using self regulation learning. The data analysis was conducted qualitatively in the form of descriptive or inferential showed by self-regulation in high category comprising 11 students or 7,09%, medium category comprising 97 students or 62,58%, and low category comprising 47 students or 30,32%. The result of this study showed that: (1) self-regulation of prospective primary school teachers was included into medium category, (2) self-regulation had an important role to improve students’ motivation.
Predicting the hybridization state: a comparative study between conventional and innovative formulae
Authors: Das Arijit
Published: November 2020

In previous published articles, formulae-based mnemonics by counting the total number of σ bonds with a lone pair of electrons (LP), a localized negative charge (LNC), or a localized lone pair of electrons (LLP) and subtracting one (01) from this total value (TSLP, TSLNC, or TSLLP) to predict the power of the hybridization state of simple molecules or ions and organic compounds, including heterocyclic compounds have been discussed. These are the innovative and time-efficient methods of enhancing student interest. Here, in this new article, the limitations of conventional formulae in comparison to the use of innovative formulae have been discussed along with the application of the hybridization state in different fields of chemical education. This article encourages students to solve multiple choice type questions (MCQs) at different competitive examinations in a time economic ground on the prediction of hybridization state of simple molecules or ions to know their normal and subnormal geometry and prediction of hybridization state of hetero atom in different heterocyclic compounds to know the planarity of the compounds, which is very essential factor for prediction of aromaticity of heterocyclic compounds. Educators can use this comparative study in their classroom lectures to make chemistry authentic and intriguing. Because the use of mnemonics in classroom lectures is an essential tool to become a distinguished educator.
Motivation to learn and employability of Vocational High School students
Authors: Tentama Fatwa , Arridha Ghazi
Published: November 2020

Motivation to learn is one of the factors that can play a role in determining student employability. This study aimed to empirically test the role of motivation to learn on student employability. The population in this study were all grade twelve students in Vocational High School 1 Dlingo Bantul Yogyakarta, which is as many as 110 students. The sample in this study was 54 grade twelve students of Vocational High School 1 Dlingo Bantul, which consisted of two classes namely fashion and wood craft classes. The selection of the research sample was made by randomization using the cluster random sampling technique. Data collection was carried out by using the employability scale and motivation to learn scale. Data analysis was conducted using Pearson product-moment analysis technique. The analysis result shows that the magnitude of the correlation coefficient (r) between motivation to learn and employability was 0.747, p = 0.000 (p 0.01). This finding indicates that there is a very significant positive correlation between motivation to learn and student employability. Motivation to learn contributes as large as 55.8 percent of employability. Thus, motivation to learn does contribute to explaining the level of employability of Vocational High School students.
Tertiary education trust fund intervention on academic staff capacity building in Lagos State University, Nigeria
Authors: Isiaka Abdulaziz , Nasiru Olokooba Issa , Olushola Iyekolo
Published: November 2020

The study adopted the descriptive survey research design to assess Tertiary Education Trust Fund intervention on academic staff capacity building in Lagos State University, Nigeria. The population for this study was all academic staff of Lagos State University. Two purposes of the study were raised and two research questions were also formulated. One hundred and ninety-six questionnaires were randomly administered to one hundred and ninety-six (196) academic staff in the university. The questionnaire titled “Tetfund Intervention on Academic Staff Capacity Building Questionnaire” was used for data collection. The findings of the study revealed that provision of infrastructure for effective teaching and learning is the major the fund intervention towards qualitative transformation of academic staff in Lagos State University. The finding of the study also showed that the fund intervention in Lagos State University for academic staff capacity building was major priority. Based on the findings of the study, it was recommended that the fund should eliminate the level of bureaucratic bottlenecks often associated with accessing approved funds. Having noted that University education is cost-effective, donor agencies and philanthropic individuals and groups, should assist governments in funding tertiary education in the country.
Impact of online course discussion on education leadership students’ reflections
Authors: Saleh Amany
Published: November 2020

Educators learn through reflection on how power shapes their own practices, expressing their concerns about the constraints they face, and brainstorming solutions to address them. Educators create and adjust their philosophies and practices by reflecting on how abstract theories manifest themselves in life. The online discussion format affords students the opportunity to improve their reflective practices through the use of structured questions, supervised scaffolding, shared experience, and opportunities to connect theory to practice. In essence, online discussions offer educators a dynamic and energetic atmosphere in which they can interact with each other. The purpose of the study was to examine the impact of  online discussions on students’ critical skills as they reflect on issues dealing with students’ diversity. The results demonstrated that the use of structured online discussions contributed to the elevation of graduate students’ reflective practices as they contemplated the social and cultural issues that impact students’ learning and their educational practices.
ICT skills, and benefits of teaching and learning animal science with blended learning at colleges of education in Ghana
Authors: Prince Dzakpasu Edem , Dewodo Christopher , Atiglah Pascal Benson
Published: November 2020

Animal science is an essential curriculum in animal husbandry and veterinary professional education. This study delved into the use of ICT in teaching animal science using blended learning and the benefits of blended learning for teachers and students. The study utilized a descriptive survey design. The target population consisted of animal science students and teachers selected colleges of education in the Volta region. The population of Agric science students was 100, and the Agric science tutors in the three colleges were 20. With the use of Yamane formula, the sample size was 80 and 19 respectively for students and the teachers. The fundamental instrument for data collection was questionnaires. Four and five scaled Likert like tests were designed to elicit information on the level of ICT skill of teachers and their students, and on benefits of blended learning to teachers and students respectively. The information gathered was analyzed using SPSS version 21 and the hypotheses were tested using Analysis of Covariance. The result established that both teachers and students of animal science department in the Colleges that participated in the study, are skilled in ICT and that both teachers and students benefited from using blended learning model in teaching animal science in colleges of education in Ghana. It was also discovered from hypothesis tested that no significant difference existed between the ICT skill level of teachers and students, and no significant difference also existed between the level of benefit derived from blended learning by both teachers and students. It was concluded that both teachers and students of animal science in the colleges of education in Ghana benefited from blended learning model because they are skilled in ICT. Hence, it was recommended that teachers and students must be well trained to acquire sufficient ICT skills in the usage of basic ICT applications in order to obtain the full benefits of the blended learning model.
Integration of strengthening of character education and higher order thinking skills in history learning
Authors: Haniah Apriliana Rusly , Aman Aman , Setiawan Risky
Published: November 2020

The purpose of this study is to find integration packages for Strengthening Character Education (PPK) and Higher Order Thinking Skills (HOTS) in history learning at SMAN 1 Yogyakarta, which includes: (1) form of integration packaging for strengthening character education in history learning, (2) forms of integration packaging higher-order thinking skills in history learning, (3) constraints and solutions for integrating strengthening of character education and higher-order thinking skills in history learning.  This research is qualitative research with a naturalistic research type. The subjects in this study were the principal, deputy headmaster of the curriculum section, history teacher, and students who were drawn using purposive sampling techniques. The results showed: (1) Integration of character education reinforcement was found in history learning, namely in the planning, implementation and evaluation stages of learning. Forms of integration packaging or containers for strengthening character education that can be seen in learning activities and attitude assessments that contain religious values, conscientious, disciplined, responsible, communicative, collaborating, confident, caring, critical thinking, nationalist and creative; (2) The packaging for integrating higher-order thinking skills in history learning is found, namely in assessment and questions as well as in learning planning. The assessment carried out is an assessment of attitudes, knowledge, and skills that are integrated with the questions by conducting KD analysis. The results of the analysis then the teacher chooses the KD that can be made about HOTS;  and (3) Obstacles that are found that are technical in inserting character values in learning activities on historical subjects that are suggested to history teachers to always participate in the Subject Teachers' Deliberation (MGMP) which is felt by researchers to be very helpful for teachers to exchange information, and sharing about the obstacles encountered. For the constraints of making assessment instruments, advice to the Principal, Teachers, and Education Office to conduct socialization and training in making assessment instruments, the grid then starts making HOTS questions
Effects of reading strategies on grade one children’s phonemic awareness performance
Authors: Melesse Solomon , Enyew Chanyalew
Published: November 2020

This study examined the effects of language teaching strategies in Amhara region, Ethiopia on children’s phonemic awareness reading performance. To this end, one hundred and two grade one children of two intact sections (n=50) and (n=52) were selected and participated as experimental and control groups, respectively. The research employed quasi-experimental pre- and post-test research design that aimed at examining the effects of reading strategies in children’s phonemic awareness performance. Besides, the researchers collected data through non-participant observation and teacher self-reflection reports. To analyze children’s phonemic awareness, paired samples t-test was computed using pre- and post-test scores of the children. To analyze the qualitative data, researchers employed narratives based on categories formed considering the basic themes of the research questions of this paper. Findings indicated that phonemic awareness reading strategies used in Amhara region could improve children’s phonemic awareness performance. Furthermore, observation and teachers’ reflections showed that there were positive results on the application of the strategies in improving children’s phonemic awareness. Eventually, recommendations and implications for further research were suggested.
Factors influencing academic participation of undergraduate students
Authors: Silalahi Sari Muthia
Published: November 2020

This study aims to examine factors influencing aspects such as teacher's personality, student's behavior, environmental which has influence student's affective and cognitive. The data were obtained using methods: interview and questionnaire. The random participant has been chosen for interviewed and population has been used for the questionnaire. There were 1585 participants have filled the questionnaire and 24 students have interviewed. Interview data were recorded and analyzed. The results have processed, it was classified according to study programs following the indicator.  The research finding shows that: factors from lecturers and teaching assistants got 78 - 81%, academic and non-academic facilities got 74.91% - 80.86% and dormitory as living for students got 69.16% which have a big impact on influencing student's affective and cognitive. There were also issues such as teacher's centered-learning, most of students and class situations can often be uncomfortable.
Predicting managerial styles: Is the Myers-Briggs Type Indicator still useful?
Authors: Diah Sari Erita Yuliasesti , Bashori Khoiruddin
Published: November 2020

The managerial ability for leaders becomes a critical matter to achieve organizational effectiveness. This study aims to describe the profile of school principals in Yogyakarta. A total of 39 principals in elementary school and senior high school participated in this study. Data was collected using the Myers-Briggs Type Indicator (MBTI) and Management Style Diagnostic Test (MSDT). The results showed that the dominant personality character is the components of openness, relationships, confidence, persistence, and combined with opportunities for creative and macro thinking. The principal's management style is dominated by Bureaucrat's type, which signifies compliance with the organization's rules and regulations and, combined with the Developer that allows a harmonious relationship between subordinate superiors to make efforts to develop.
Urgency of Adiwiyata School for education as sustainable development
Authors: Susilawati Wiwik Okta , Darniyanti Yulia , Prasetyo Dian Estu , Apreasta Lika , Novitasari Ana
Published: November 2020

This research is intended to be understood; 1) the urgency of education as an environmentally sustainable development; 2) the background of implementing the adiwiyata school program at SMP Muhammadiyah 3 Yogyakarta; and 3) the implementation of the adiwiyata school program at SMP Muhammadiyah 3 Yogyakarta. The research used in this research is qualitative research. The research subjects were the chief coordinator of the adiwiyata team, and the teacher. Determination of research subjects is done by purposive sampling technique. Data collection techniques were carried out using interview, observation and documentation methods. This type of data analysis uses the Milles Huberman model, namely reduction, data display, and drawing conclusions/verification of data. The results of this study are; 1) The concept of sustainable development is related to ethical issues, the discussion of the concept of sustainable development in the future (future) and also focuses on the problem of welfare (poverty); 2) There are a number of things underlying the implementation of the adiwiyata school program at SMP Muhammadiyah 3 Yogyakarta, both the overall background, philosophical, geographical, juridical, both organizational background; and 3) To support the growth of the values of attention problems in SMP Muhammadiyah 3 Yogyakarta can use four aspects of the Adiwiyata program, such as environmentally sound policies, implementation of environment-based policies, participatory based planning activities and management of environmentally friendly supporting facilities.
Philosophical review of heredity and environment in Islamic education
Authors: Mansir Firman , Parinduri Muhammad Abrar , Tumin Tumin , Hatmanto Endro Dwi
Published: November 2020

This research explains that heredity affects the formation of personality. However, it is not the only one absolute factor which can’t be changed. In fact, personality can be supple and the tool to change is the environment. The purpose of this study is to show that heredity and environment are important in determining the quality of individual character development in Islamic education studies. In the teachings of Islam, both sourced through the Quran, the Hadith of the Prophet, and the opinions of other experts, although not explicitly stated, there are also several sources that explain and justify that heredity and the environment can affect the growth of character and behavior human behavior. Both heredity and the environment have a very significant relation either individually and together in the education process. Thus, in the world of education a teaching and learning strategy, it is needed to be able to accommodate human and religious values. In other words, humanitarian and religious values are inseparable wither in transfer of knowledge, transfer of value and transfer of method. Therefore the method in this research is uses research type/approach of library research.
A study analysis of student attitude to science lessons
Authors: Tanti Tanti , Kurniawan Dwi Agus , Anggraini Lika , Perdana Rahmat
Published: November 2020

An attitude is a form of one's perception of an object that is described with expressions of like or not. The purpose of the study was to describe the attitudes of students towards the three indicators of the attitude of the junior high school in Batanghari. The research method uses quantitative survey research. The instrument used was a questionnaire that focused on three indicators consisting of 18 statements and also interviews. The sample in this study was 280 students in Batanghari. The results of research on three attitude indicators which became the dominant focus of research in the good category. The Social Implications of the Science show a good category with a percentage of 57.9%. The pleasure of science learning is well categorized with a percentage of 45.4%. The attitude towards the science investigation is categorized sufficiently with the percentage category of 41.1%. From the research that has been carried out, it can be seen that the attitude of students in junior high school is categorized as good, because the three indicators examined show good categories.
The contribution of future orientation towards employability in students of vocational high school
Authors: Tentama Fatwa , Nabilah Bella Rifqi
Published: November 2020

The employability of students in vocational high schools is a major concern that must be considered. Employability as the ability and skills that will make it easier for individuals to get a job. Future orientation is one of the factors that can affect employability. This study aims to test the role of future orientation on student employability empirically. The population in this study were all students of class XII at Vocational High School Piri 1 Yogyakarta, totaling 150 students. The sample in this study amounted to 58 students and selected using cluster random sampling techniques. The research method used is a quantitative method with a scale of employability and a scale of future orientation. Analysis of the data used in this study is the product-moment analysis technique. The results of data analysis showed that there was a very significant positive correlation between future orientation towards employability with r = 0.636 and significance level (p) = 0.000 (p 0.01). Future orientation contributes 40.5% to employability, and the remaining 59.5% is influenced by other variables.
Effect of Variability in Blood Pressure, Glucose and Cholesterol Concentrations, and Body Weight on Emergency Hospitalization and 30‐Day Mortality in the General Population
Authors: Lee Seung‐Hwan , Han Kyungdo , Kwon Hyuk‐Sang , Yoon Kun‐Ho , Kim Mee Kyoung
Published: November 2020

Background

Variability in blood pressure, glucose concentration, cholesterol concentration, or body weight is associated with a wide range of health outcomes. We hypothesized that high variability in metabolic parameters is associated with an increased risk of emergency hospitalization and mortality.

Methods and Results

Using a nationally representative database from the Korean National Health Insurance System, 8 049 228 individuals who underwent 3 or more health examinations during 2005 to 2010 were followed up until the end of 2016. Variability in fasting blood glucose and total cholesterol concentrations, systolic blood pressure, and body weight was measured using the variability independent of the mean (VIM). High variability was defined as the highest quartile of variability. Subjects were classified according to the number of high variability parameters. The end points of the study were emergency hospitalization and 30‐day mortality. There were 733 387 emergency hospitalizations (9.1%) during a median follow‐up of 5.6±1.2 years. For each metabolic parameter, an incrementally higher risk of emergency hospitalization was observed for higher VIM quartile groups than for the lowest quartile group. Compared with the group with low variability for all 4 parameters, the group with high variability for all 4 parameters had a significantly higher risk for emergency hospitalization (hazard ratio [HR], 1.58; 95% CI, 1.54–1.61) and 30‐day mortality (HR, 2.44; 95% CI, 1.62–3.69), after adjusting for possible confounding factors.

Conclusions

High variability in metabolic parameters was associated with increased risk of emergency hospitalization and short‐term mortality.
Studying Islam in Western and Non-Western Contexts
Authors: Hughes Aaron W.
Published: November 2020

This essay provides an introduction to the following set of papers that deal with some of the methodological and theoretical issues that the study of Islam poses for the academic study of religion. It argues that, while still somewhat problematic, recent years have seen a number of younger scholars—particularly in Europe and the so-called Muslim World—engage in and wrestle with these theoretical issues. The result is that the study of Islam has come a long way since the apologetic aftermath of September 11, 2001.
Revision of the Oriental tiger beetle genus Heptodonta Hope, 1838 (Coleoptera: Cicindelidae)
Authors: GÖRN SEBASTIAN
Published: November 2020

This contribution aims to revise the taxonomy of the genus Heptodonta Hope, 1838, and provides a dichotomous key to the 15 species of this genus. Each species is described in detail with colour photographs of habitus and diagnostic characters. Information on distribution and biology of each species is provided. Heptodonta abasileia sp. nov., H. halensis sp. nov., H. horii sp. nov., H. schuelei sp. nov., H. tempesta sp. nov. and H. wiesneri sp. nov. are described. Heptodonta nigrosericea (W. Horn, 1930), stat. nov. is raised to species rank. Heptodonta ferrarii Gestro, 1893, syn. nov. and H. ferrarii shooki Wiesner, 1986, syn. nov. are placed into synonymy under H. pulchella (Hope, 1831). Heptodonta lumawigi Wiesner, 1980, syn. nov. is placed into synonymy under H. nigrosericea stat. nov. Females of H. vermifera W. Horn, 1908, and males of H. mindoroensis Cassola, 2000, are described for the first time. Lectotypes are designated for H. analis (Fabricius, 1801), H. arrowi W. Horn, 1900, H. ferrarii Gestro, 1893, H. hopei Parry, 1844, H. melanopyga (Schaum, 1862), H. nigrosericea (W. Horn, 1930), H. posticalis (White, 1844), H. pulchella (Hope, 1831), H. thongdii Fleutiaux, 1919, H. variipes (Chaudoir, 1850), H. vermifera W. Horn, 1908, and H. yunnana (Fairmaire, 1887). Holotype is designated by monotypy for H. eugenia Chaudoir, 1865. Regionally restricted records of two new species from the Philippine island Negros and one new species from the northeast Indian Garo Hills highlight the high conservation value of these rather small-scale regions.
Using Radiomic Features to Predict Visual Prognosis of Idiopathic Macular Hole Surgery
Authors: Zhao Zhuoran , Zhu Jun , Xu Yi , Geng Xingyun
Published: November 2020

Idiopathic macular holes (IMH) are a leading cause of vision loss in middle-aged and older people. IMH is usually treated surgically by vitrectomy. Improvement in visual acuity is used to assess the prognosis of macular hole surgery. To achieve better diagnosis and treatment of IMH,
Optical coherence tomography (OCT) technology is widely used. It will improve patient outcomes if parameters that are correlated with favorable prognoses are identified in OCT images. Both 2D OCT images and 3D OCT images can be obtained, which allows for the possibility of extracting 3D features.
We propose the use of radiomic features as predictors of IMH prognosis. In this study, radiomic techniques were used to identify shape and texture features of IMH. OCT images were sliced into 2D images to enable experts to segment the region of interest before feature extraction. Elements
of an initial set of mined features were selected as predictors based on correlation analysis and least absolute shrinkage and selection operator data analysis. P-values between selected features and best-corrected visual acuity were calculated to identify significant features. Nine
features were found that influence surgical outcomes. Receiver operating characteristic curve analyses of positive samples (post-surgical visual outcome improved more than 0.3) and negative samples (all nonpositive samples) showed the area under the ROC curve of the radiomic feature set reached
0.81. Analysis showed that radiomic features of preoperative OCT images accurately predict visual prognosis, and thus identifying the features can be a powerful diagnostic technique.
Medical Quality Control in a General Hospital Based on Plan-Do-Check-Act Cycle
Authors: Hu Xinxin , Shen Leichai , Wen Jing , Chen Ren , Wang Heng , Kan Ming , Shen Mi
Published: November 2020

Objective: There are many difficulties for health information management in large general hospital. The aim of this study is to provide an objective basis for better application of Plan-Do-Check-Act (PDCA) cycle quality management mode in the hospital medical quality control.
Method: The PDCA cycle were applied in all the departments in a large general hospital. The main evaluation indicators before and after application of PDCA was compared and comprehensively analyzed. Result: The main evaluation indicators in various departments can reflect the
differences before and after application of PDCA. After the application of PDCA, the main evaluation indicators were improved in all the departments (P < 0.05). The improvement of doctor's theoretical knowledge level and the medical quality basic indicators compliance rate need the
continuous application of PDCA for at least one year. Conclusion: The perfection of PDCA can promote continuous improvement of medical quality management in various departments, so as to improve the hospital medical quality.