bluuebunny/crossref_metadata_2025 huggingface dataset:
Finite groups with given systems of generalised σ-permutable subgroups
Authors: Zakrevskaya Viktoria S.
Published: December 2021

Let σ = {σi|i ∈ I } be a partition of the set of all primes ℙ and G be a finite group. A set ℋ  of subgroups of G is said to be a complete Hall σ-set of G if every member ≠1 of ℋ  is a Hall σi-subgroup of G for some i ∈ I and ℋ contains exactly one Hall σi-subgroup of G for every i such that σi ⌒ π(G)  ≠ ∅.  A group is said to be σ-primary if it is a finite σi-group for some i. A subgroup A of G is said to be: σ-permutable in G if G possesses a complete Hall σ-set ℋ  such that AH x = H  xA for all H ∈ ℋ  and all x ∈ G; σ-subnormal in G if there is a subgroup chain A = A0 ≤ A1 ≤ … ≤ At = G such that either Ai − 1 ⊴ Ai or Ai /(Ai − 1)Ai is σ-primary for all i = 1, …, t; 𝔄-normal in G if every chief factor of G between AG and AG is cyclic. We say that a subgroup H of G is: (i) partially σ-permutable in G if there are a 𝔄-normal subgroup A and a σ-permutable subgroup B of G such that H = < A, B >; (ii) (𝔄, σ)-embedded in G if there are a partially σ-permutable subgroup S and a σ-subnormal subgroup T of G such that G = HT and H ∩ T ≤ S ≤ H. We study G assuming that some subgroups of G are partially σ-permutable or (𝔄, σ)-embedded in G. Some known results are generalised.
Deterministic and stochastic models of infection spread and testing in an isolated contingent
Authors: Chigarev Anatoliy V. , Zhuravkov Michael A. , Chigarev Vitaliy A.
Published: December 2021

The mathematical SIR model generalisation for description of the infectious process dynamics development by adding a testing model is considered. The proposed procedure requires the expansion of states’ space dimension due to variables that cannot be measured directly, but allow you to more adequately describe the processes that occur in real situations. Further generalisation of the SIR model is considered by taking into account randomness in state estimates, forecasting, which is achieved by applying the stochastic differential equations methods associated with the application of the Fokker – Planck – Kolmogorov equations for posterior probabilities. As COVID-19 practice has shown, the widespread use of modern means of identification, diagnosis and monitoring does not guarantee the receipt of adequate information about the individual’s condition in the population. When modelling real epidemic processes in the initial stages, it is advisable to use heuristic modelling methods, and then refine the model using mathematical modelling methods using stochastic, uncertain-fuzzy methods that allow you to take into account the fact that flow, decision-making and control occurs in systems with incomplete information. To develop more realistic models, spatial kinetics must be taken into account, which, in turn, requires the use of systems models with distributed parameters (for example, models of continua mechanics). Obviously, realistic models of epidemics and their control should include models of economic, sociodynamics. The problems of forecasting epidemics and their development will be no less difficult than the problems of climate change forecasting, weather forecast and earthquake prediction.
On rational Abel – Poisson means on a segment and approximations of Markov functions
Authors: Patseika Pavel G. , Rouba Yauheni A.
Published: December 2021

Approximations on the segment [−1, 1] of Markov functions by Abel – Poisson sums of a rational integral operator of Fourier type associated with the Chebyshev – Markov system of algebraic fractions in the case of a fixed number of geometrically different poles are investigated. An integral representation of approximations and an estimate of uniform approximations are found. Approximations of Markov functions in the case when the measure µ satisfies the conditions suppµ = [1, a], a > 1, dµ(t) = φ(t)dt and φ(t) ≍ (t − 1)α on [1, a], a are studied and estimates of pointwise and uniform approximations and the asymptotic expression of the majorant of uniform approximations are obtained. The optimal values of the parameters at which the majorant has the highest rate of decrease are found. As a corollary, asymptotic estimates of approximations on the segment [−1, 1] are given by the method of rational approximation of some elementary Markov functions under study.
Synthesis of quantum circuits based on incompletely specified functions and if-decision diagrams
Authors: Prihozhy Anatoly A.
Published: December 2021

The problem of synthesis and optimisation of logical reversible and quantum circuits from functional descriptions represented as decision diagrams is considered. It is one of the key problems being solved with the aim of creating quantum computing technology and quantum computers. A new method of stepwise transformation of the initial functional specification to a quantum circuit is proposed, which provides for the following project states: reduced ordered binary decision diagram, if-decision diagram, functional if-decision diagram, reversible circuit and quantum circuit. The novelty of the method consists in extending the Shannon and Davio expansions of a Boolean function on a single variable to the expansions of the same Boolean function on another function with obtaining decomposition products that are represented by incompletely defined Boolean functions. Uncertainty in the decomposition products gives remarkable opportunities for minimising the graph representation of the specified function. Instead of two outgoing branches of the binary diagram vertex, three outgoing branches of the if-diagram vertex are generated, which increase the level of parallelism in reversible and quantum circuits. For each transformation step, appropriate mapping rules are proposed that reduce the number of lines, gates and the depth of the reversible and quantum circuit. The comparison of new results with the results given by the known method of mapping the vertices of binary decision diagram into cascades of reversible and quantum gates shows a significant improvement in the quality of quantum circuits that are synthesised by the proposed method.
Biological education in Belarusian State University for 100 years
Authors: Demidchik Vadim V. , Tikhomirov Valery N. , Matskevich Vera S. , Sakhvon Vitaly V. , Ditchenko Tatyana I. , Popinachenko Irina M. , Buga Sergey V. , Grichik Vasily V. , Evtushenkov Anatoly N. , Maximova Natalia P. , Prokulevich Vladimir A. , Semak Igor V. , Smolich Igor I. , Chumak Anatoly G. , Lysak Vladimir V.
Published: December 2021

The article is dedicated to the centenary of Belarusian State University and the centenary of biological university education in Belarus. The history of the faculty of biology is described, a retrospective of the development of its units since 1921 is presented. The most significant personalities and events are highlighted. The inseparable connection between the life of the faculty and the university as a whole is demonstrated.
Physiological and biochemical mechanisms of plants resistance to oxidative stress under peptide elicitor AtPep1
Authors: Filiptsova Halina G. , Yurin Vladimir M.
Published: December 2021

The effect of the peptide elicitor AtPep1 on the resistance of soybean and pea plants to oxidative stress was studied. The concentration of the peptide 10– 9 mol/L has the maximum elicitor effect on these plants. It was shown that treatment of the aerial part of seedlings with this peptide leads to an increase in the activity of peroxidase and superoxide dismutase and a decrease in the level of lipid peroxidation products in plants under oxidative stress. Revealed effects cause an increase in the plants resistance to stress.
The influence of the stereotypic forms of activity in mice behaviour in standard behavioural tests
Authors: Avimova Kseniya P. , Sandakov Dmitry B.
Published: December 2021

Laboratory animals often develop abnormal repetitive (stereotypic) behaviour that can influence both physiology and behavioural test results. Such abnormal behaviours usually develop in suboptimal environment and increase over time. To explore the development of stereotypic forms of activity night home-cage behaviour of laboratory mice was analysed and collated with the behaviour in open field (OFT), hole-board (HBT) and tail suspension (TST) tests twice within 16 weeks. Mice expressed few stereotypies and their duration lessened over time from median 8.2 to 1.0 %. In contrast, grooming behaviour increased significantly from 29.5 to 49.6 %. Home-cage grooming correlated with the latency of locomotion start in OFT and with the immobility time in TST. Intensity and stability of stereotypic activity and grooming inf­luenced the duration of grooming in OFT: the mice with unstable stereotypies groomed more than others, and mice with the lowes home-cage grooming level also groomed in OFT the most. Intensity and stability of night grooming influenced the behaviour in TST: the mice with unstable level of grooming were the most mobile in this test. Abnormal home-cage activity may indicate impaired welfare, and that, in turn, may affect test activity, so researchers need to keep it in mind when planning animal behaviour experiments.
Phytopathogenic micromycetes on alien plants from the publication «Black book of the flora of Belarus: alien harmful plants»
Authors: Poliksenova Valentina D. , Khramtsov Alexander K. , Hirilovich Ivan S. , Lemeza Nikolai A. , Sidorova Svetlana G. , Stadnichenko Marina A.
Published: December 2021

The 228 species of phytopathogenic micromycetes parasitising alien plants included in the publication «Black book of the flora of Belarus: alien harmful plants» (Minsk, 2020) were identified in the course of the conducted research. It was found that out of 322 plant species listed in this edition phytopathogenic micromycetes were found on 182 species (56.5 %). It is noted that among the phytopathogenic micromycetes only 92 species and intraspecific taxon (40.4 %) belong to the alien species of the Republic of Belarus. Obviously, these phytopathogens are highly specialised and currently parasitise only on these invasive plant species. The remaining 136 species and intraspecific taxon (59.6 %) affect both native and alien plant species.
Criteries and prospects of diamonds of the Vitebsk granulite massif
Authors: Konishchev Victor S. , Kovkhuto Andrei M.
Published: December 2021

The article describes the history of studying the diamond content of tectonic structures of the territory of Belarus. Based on the results of magnetometric, mineralogical, tectonic studies carried out by industrial geologists and scientists over the past 50 years, new scientifically substantiated criteria for the search for explosion pipes have been developed using Clifford’s rule, according to which kimberlite explosion pipes are developed within the Archean cratons, where the thickness of the lithosphere is 175–270 km, and are absent in the zones of Early Proterozoic stabilisation and tectonomagmatic activation. Explosion tubes on the African-Arabian, East Siberian, Sino-Korean and East European platforms demonstrate their confinement to the Archean cratons and may be associated with zones of paleosubduction of the Proterozoic oceanic crust beneath the Archean cratons. Based on this, the authors scientifically substantiated the hypothesis that during the closure of the Early Proterozoic paleoocean separating the Fenno-Scandinavian craton from the Volga-Ural and Sarmatian cratons, subduction of the younger crust took place under these cratons, the southwestern corner of which on the territory of Belarus is the Vitebsk granulite massif. The article concludes that the Vitebsk granulite massif is the most promising in terms of diamond-bearing on the territory of Belarus, and within its limits – the Smolensk regional deep fault at the intersection of this fault of northeastern striking with the Odessa-Gomel regional deep fault of submeridional striking south of the city of Orsha. Recommendations are given for further study of promising areas in order to determine their diamond content.
Methods of modelling of socio-economic phenomena – method of constructing multiple spirals and multimodal analysis
Authors: Shcherbin Vyacheslav K.
Published: December 2021

The article considers the methods of semiotic modelling (method of constructing multiple spirals, and multimodal analysis, etc.). The relevance of the use of these methods for the study of socio-economic phenomena is determined. Features of the use of these methods are described with help of two groups of key notions: a) the group of concept-variables of such concepts as code (genetic, iconic, information, cultural, memetic, social, civilisation, language), gene (biological, cultural, social, philosophic, economic), spiral (Archimedes, double, multiple, plane, spatial, triple, etc.); b) the group of concept-variables of such concepts as modalisation, modality, mode and multimodality. Differences between the methods under consideration are due not only to the different sets of concepts used to describe them, but also due to the main objects studied using these methods. So, as the main object of modeling using the method of constructing multiple spirals, various types of such complex signs as codes and genes are most often used. The objects of multimodal analysis are, as rule, macrolevel semiotic units (video, comic books, creolised and poly-code texts, posters, and other polymodal texts). The conclusion is substantiated that the method of constructing multiple spirals and multimodal analysis, together with the previously considered semiotic and chain analyses, form a single methodological system of social semiotics.
Can anomie be normal?
Authors: Kavetski Sviatoslav T.
Published: December 2021

The idea of rediscovering anomie is analysed, which is associated with the influence of acceleration and complication of modern society. The category of «normal anomie», which is understood as an expanding set of vulnerabilities for society in the form of side effects of innovative, rational-pragmatic human activity, is being investigated in a discussion form. The article is subject to critical rethinking of the transformation processes today. Social practices of «normal anomie» in Belarus are revealed through the prism of sociological research. The author brings up the concept of total anomie for discussion of the sociological community.
Anaesthetic Management of Hemiparesis Patient with Severe Thoracolumbar Scoliosis for Orthopaedic Surgery by Taylor's Approach of Lumbar Subarachnoid Block in the era of COVID 19 Pandemic
Authors:   Assistant professor, Department of Anaesthesiology, SUT Academy of Medical Sciences, Thiruvananthapuram, kerala, India., P Veena , R Mohankumar ,   Assistant professor, Department of Anaesthesiology, SUT Academy of Medical Sciences, Thiruvananthapuram, kerala, India., P Geethakumari ,   Assistant professor, Department of Anaesthesiology, SUT Academy of Medical Sciences, Thiruvananthapuram, kerala, India., R Arun ,   Assistant professor, Department of Anaesthesiology, SUT Academy of Medical Sciences, Thiruvananthapuram, kerala, India.
Published: December 2021

Background: Subarachnoid block in patients with scoliosis always present a unique challenge to the anesthesiologist owing to the deformity of spine. Difficulty in performing neuraxial anaesthesia may result in neural injury, spinal haematoma, post-dural puncture headache In addition, it may decrease procedure efficiency and increase patient discomfort and dissatisfaction. The most commonly practiced technique is the midline approach. This approach is technically difficult in the geriatric patients because of degenerative changes in the spine. Calcification of supraspinous and interspinous ligaments in the geriatric age group makes midline approach difficult. Paramedian approach and its modification Taylor’s approach is not routinely practiced and is definitely a game changer when midline approach of lumbar subarachnoid block has failed or is not possible due to anatomical variations like ankylosing spondylitis, thoracolumbar kyphoscoliosis. We report a case of unilateral hemiparesis patient with severe thoracolumbar scoliosis anaesthetically managed by Taylor’s approach of lumbar Subarachnoid block for Proximal Femur Nailing (PFN) of intertrochanteric fracture thus avoiding general anaesthesia and associated aerosol generation in the era of COVID19 pandemic.
Terrorist Discourse: A Semiotic and Critical Discourse Analysis of ISIS Jihadi Videos
Authors: Harb* Grasiella K. , Khoury Nadim
Published: December 2021

The Islamic State of Iraq and Syria (ISIS) videos have shown unprecedented professionalism in communicating fear and enlisting members to the organization. Unfortunately, counter-media campaigns failed to have a lasting defeat for the organization’s social and cognitive impact on the public. Accordingly, the present qualitative study aims to explore how the use of the multiple communication modes in ISIS videos makes the organization’s ideology appealing and intimidating. The study employs Kress and van Leeuwen’s social semiotic framework as well as Fairclough’s and van Dijk’s model of critical discourse analysis for analyzing one of ISIS videos that resulted in a global outrage. The findings are significant for understanding how the terrorists’ communication strategies are embedded in their professional media techniques. A deep understanding of the ISIS technique has an impact on creating successful counter-media campaigns that persuade the public to resist any new wave of terrorism.
Ekstrak Daun Jeruk Purut (Citrus hystrix D.C) Mampu Menghambat Pertumbuhan Candida albicans
Authors: Sophia Anggun , Suraini Suraini , Pangestu Mahmud Wahyu
Published: December 2021

Ekstrak daun jeruk purut mengandung beberapa komponen aktif seperti saponin, polifenol, flavonoid dan tanin yang dapat menghambat pertumbuhan jamut. Tujuan penelitian ini untuk menguji ekstrak daun jeruk purut sebagai senyawa penghambat pertumbuhan Candida albicans dan memperoleh konsentrasi ekstrak daun jeruk purut paling baik dalam menghambat pertumbuhan Candida albicans. Manfaat penelitian ini untuk menguji ekstrak daun jeruk purut dan konsentrasi yang paling baik dalam menghambat pertumbuhan Candida albicans. Penelitian ini menggunakan penelitian ekperimental laboratorium dengan rancangan acak lengkap dengan berbagai konsentrasi ekstrak 10%, 20%, 40% 80% sebagai perlakuan dan dibandingkan dengan kontrol positif ketokonazol serta kontrol negatif Carboxymethyl cellulose (CMC) dengan 6 pengulangan. Hasil pengukuran diameter zona hambat Candida albicans di uji menggunakan uji statistic One way Anova (Analysis of variance) selanjutnya dilakukan uji duncan’s pada taraf 5%. Analisis terhadap hasil penelitian mengidentifikasi ekstrak daun jeruk purut mampu memberikan penghambatan terhadap Candida albicans. Penghambatan pertumbuhan terbaik ditunjukkan pada perlakuan ekstrak 80% dengan rerata diameter koloni 3.69±0.14 cm dan ketokonazol sebagai kontrol positif 4.40 cm. Dengan demikian, ekstrak daun jeruk purut berpotensi untuk menghambat pertumbuhan Candida albicans.
USING QUIZIZZ GAME TO IMPROVE STUDENT’S VOCABULARY MASTERY IN GRADE VIII C AT MTs IBNU ROSYAD
Authors: Komalasari Nila , Zuhriyah Mukminatus
Published: December 2021

The Covid-19 pandemic situation made the government announce the use of e-learning. With this policy, teachers are expected to apply interesting media to be studied. This research aimed to find out whether or not Quizizz Game could improve students’ vocabulary mastery and the supporting and inhibiting factors of the success of Quizizz Game implementation. It was a collaborative Classroom Action Research (CAR). The subject of this research was grade VIII-C of MTs Ibnu Rosyad in the academic year of 2020/2021 which consisted of 20 students. This research was conducted in two cycles which each consists of planning, acting, observing, and reflecting. The data were gathered through qualitative and quantitative data. The results of this research showed that there was improvement from cycle 1 to cycle 2. It can be seen from the mean score of pre-test were 53, the mean score of post-test 1 was 69 and the mean score of post-test 2 was 84. The students' attention and motivation also helped use of Quizizz. But, limited school facilities and wifi become the obstruction
Pendidikan Umat dan Potensi Gerakan Sosial Online di Era Pandemi COVID-19
Authors: Maliki Musa
Published: December 2021

Many issues are emerging during Covid-19 pandemic and one of them is mobility restriction. Some of society engagement research were still conducted in physical format with strict health protocols and some others were using hybrid methods of society engagement, combining offline and online activities. The purpose of this study is to provide an alternative way to deal with the pandemic. During pandemic, it is difficult to reach Indonesian society directly. This study conducted a series of full virtual interaction, in collaboration with the Leading Intellectual Network Community (JIB) supported mostly by Muhammadiyah young generation. The targeted audience of this society engagement were active members of JIB, its followers, and Islamic community in Indonesia at large. It focusses on actual discussion related to Covid-19 pandemic in the form of educative talk show to build public awareness. We invite credible speakers such as medical researchers, voluntary doctor on Covid-19, social scientists, and public policy advisor. This society engagement was based on Zoom platform that was broadcasted through JIB POST official website, YouTube, Facebook, and Instagram. These activities were evaluated and received feedback from WhatsApp Group JIB; expression of engagement of the audience based on subscribe, like, viewers, dan comments; and a report news on JIB POST official website. The activities presented a good result which are reaching the target of a thousand subscribers on the social media and hundreds of viewers with many positive responses from the members of JIB for every talk shows.
Pancasila dan Perdagangan di Era Globalisasi: PkM di PKBM Bhakti Asih, Ciledug, Kota Tangerang
Authors: Lubis Iman , Syamruddin Syamruddin , Sopandi Andi , Sukapti Sri , Rahman Fathur
Published: December 2021

This Community Service (CS) aims to reduce understanding of Pancasila in the era of globalization when the economy makes goods, services and culture freely flow between countries. The method used is lecture and question and answer discussion. The tool used is google meet. The meeting was conducted boldly. The implementation is carried out in four stages, namely survey, pre-activity, implementation, and PKM report. The target achievement in this CS is that participants can recall about Pancasila so that their behavior can reflect Pancasila. The discussion implemented in PKBM Bhakti Asih is the material of Pancasila and its origins, the dimensions of the globalization era of marketing, human resources, and finance and international trade.
Pendampingan Pembuatan Bahan Ajar Atraktif Bagi Tenaga Pengajar Sebagai Penunjang Pembelajaran Siswa/Siswi SMA BP FAI UMJ Muhammadiyah Boarding School "Ki Bagus Hadikusumo"
Authors: Rialmi Zackharia , Wahyuni Fitri , Ferdyanto Ferdyanto
Published: December 2021

The use of technology in education is a necessity that cannot be avoided. Information technology-based learning such as presentations using Microsoft Power Point is an interesting process for students. Teaching materials/materials delivered using Microsoft power point can help students understand the material being taught. Generation Z as a generation that is already familiar with technological advances, of course, is also familiar with this technology. This affects their learning process. Visual learning style by relying on visual acuity is a mainstay for generation Z in the learning process. Attractive media and teaching materials will help them understand the material being studied. High school students BP FAI UMJ Muhammadiyah Boarding School (MBS) "Ki Bagus Hadikusumo" are included in generation Z who like visual learning styles. Therefore, the teaching staff of SMA BP FAI UMJ Muhammadiyah Boarding School (MBS) "Ki Bagus Hadikusumo" needs to deepen the use of attractive learning media in delivering material so that students more easily understand the subject. In this mentoring activity, it is expected that the teaching staff can explore the features in Microsoft Power Point so that they can create attractive teaching materials that can be implemented in the teaching and learning process in class or online.
Pelatihan Penulisan Naskah Ilmiah Jurnal Investigasi Bagi Guru-Guru Se-Kota Tangerang Selatan
Authors: Kusjono Gatot , Suprianto Suprianto , Maddinsyah Ali , Syamruddin Syamruddin , Widodo Sugeng
Published: December 2021

Community service activities. Scientific Manuscript Writing Training Journal of Educational Research at SMP Negeri 17 Tangerang Selatan aims to help elementary/junior/junior high school teachers in South Tangerang City in writing scientific manuscripts that will be published in ISSN journals. The training method is carried out using the method of mentoring, discussion, workshops and technical guidance (bimtek) of writing scientific manuscripts in accordance with journal manuscript standards. The results of the training were obtained as many as 11 elementary school teacher manuscripts (73%) and 4 junior high school teacher manuscripts (27%) published in the INVESTIGATION journal of SMP Negeri 17 Tangerang Selatan Volume 2 Number 2 Month September 2021 - December 2022. Publishing teacher scientific manuscripts in the INVESTIGATION journal is certainly very important. assisting teachers in fulfilling their obligations to journalize their scientific texts, so that they are not constrained in promotion of class or position. The targeted output in this community service activity is the publication of the results of community service activities in national scientific journals with ISSN.
What the Tortoise Said to Achilles: Lewis Carroll’s paradox in terms of Hilbert arithmetic
Authors: Penchev Vasil
Published: December 2021

Lewis Carroll, both logician and writer, suggested a logical paradox containing furthermore two connotations (connotations or metaphors are inherent in literature rather than in mathematics or logics). The paradox itself refers to implication demonstrating that an intermediate implication can be always inserted in an implication therefore postponing its ultimate conclusion for the next step and those insertions can be iteratively and indefinitely added ad lib, as if ad infinitum. Both connotations clear up links due to the shared formal structure with other well-known mathematical observations: (1) the paradox of Achilles and the Turtle; (2) the transitivity of the relation of equality. Analogically to (1), one can juxtapose the paradox of the Liar (for Lewis Carroll’s paradox) and that of the arrow (for “Achilles and the Turtle”), i.e. a logical paradox, on the one hand, and an aporia of motion, on the other hand, suggesting a shared formal structure
A Policy Brief on Vocational and Technical Education in Turkey
Authors: Karabatman Hilal Ayan
Published: December 2021

The importance of vocational and technical education (VTE) is increasing in response to the rapidly changing information, technology, production methods, and developments in every aspect of life. The only way to survive in this age and to compete with this challenge is to continuously develop comprehensive educational policies that relate to each other (MoNE, 2018). In this sense, VTE has a very central role in providing societies with the knowledge and skills that the 21st century requires (Çınar, Döngel, & Söğütlü, 2009). For this reason, in educational policy discussions, an area that requires as much attention as other areas of education is VTE. This paper aims to review the current problematic states of VTE in Turkey and make recommendations for improving it.
Mesleki Eğitimin Sorunları Bağlamında İmam Hatip Liselerinde Meslek Dersleri ve Öğretimi Üzerine Bir Analiz
Authors: KARAMAN Davut
Published: December 2021

Bu tebliğ, İmam hatip okullarında meslek dersleri ve öğretimi ile ilgili sorunları öğrenciler üzerine yapılan araştırmalarla incelenmesini amaçlamaktadır. Tebliğin oluşturulmasında literatür taraması tercih edilmiştir. İmam hatip okullarının toplumun akademik anlamda ve din öğretimi ile ilgili ilgi, istek ve beklentilerine cevap verme oranı ile bağlantılı olarak okul ve öğrenci sayılarında artış yaşandığı görülmektedir. Proje okul uygulamaları sayesinde imam hatip okullarındaki akademik başarının artması ile birlikte öğrencilerin manevi yönünü destekleyen meslek dersleri ve öğretiminin durumu hakkında çalışmaların yapılması önem arz etmektedir. Bu amaçla hazırlanan bu tebliğde meslek dersleri ve öğretimine ilişkin imam hatip lisesi öğrencileri üzerine yapılan araştırmalarda; öğrencilerin meslek derslerine olan ilgilerinin zayıf olduğu, meslek derslerinin işleyiş yönteminin öğrencilerin ilgisini çekmediği, meslek dersleri öğretmenlerinin rol model olma konusundaki zayıflığı ve meslek derslerinin sayısının ve ders saatlerinin ders programlarında azaltılması gerektiği gibi hususların çoğunlukla öne çıktığı görülmektedir.
Mesleki Yeterlilik Sistemi Çerçevesinde Test ve Belgelendirme Merkezlerinin Rolü ve Önemi
Authors: Arslan İ. Kahraman
Published: December 2021

Türkiye gibi gelişim dinamiklerinin yanı sıra, toplumun değişim talepleri ile kendine özgü çeşitli ihtiyaçları ve sorunları olan ülkelerde işsizlik ve istihdam sorunu, en öncelikli ve en önemli sorunlar arasında yer almaktadır. İstihdam artışının önündeki engellerin başında ise, işgücü piyasasının talepleri ile eğitim istihdam arasındaki ilişkinin zayıflığı ya da yetersizliği yer almaktadır. Türk mesleki eğitim kurumları, iş piyasalarındaki gelişim ve değişimin hızına ayak uyduramamıştır. Örgün ve yaygın eğitim sonunda objektif, güvenilir ve geçerli bir ölçme-değerlendirme sisteminin bulunmayışı, mesleki eğitim kurumlarının etkinliğini ve verimliliğini azaltan bir unsur olmuştur. Bu önemli soruna çözüm olarak Ulusal Yeterlilik Sistemi (UYS) geliştirilmiş ve uygulamaya konulmuştur. UYS, çeşitli meslekler için uluslararası denklik sağlayarak işgücünün serbest dolaşımını mümkün kılan, ulusal meslek standartlarına ve mesleki yeterliliklere dayalı bir sistemdir. Bu sistem sayesinde mesleki deneyimini veya mesleki yeterliliğini kanıtlayamayan kişilerin ilgili mesleği icra etmesi mümkün olamamaktadır. Ayrıca, işverenlerin nitelikli insan gücü ihtiyacını karşılayarak işletmelerin rekabet gücünü artıran, bireylere de çalışma alanı ile ilgili güvence sağlayan, adil, şeffaf ve güvenilir bir sistem olması amaçlanmıştır.
Kalkülüs Derslerinde Geogebra Fonksiyonlarından Nasıl Yararlanılabilir?
Authors: Özkale Abdullah
Published: December 2021

Teknoloji destekli matematik eğitiminde farklı program ve aplikasyonların etkilerinin genişletilmesi perspektifinde bu çalışmada lisans/önlisans düzeyinde ele alınan kalkülüs dersleri için örnek etkinlikler ele alınmaktadır. Bu çalışmanın amacı kalkülüs dersleri için hazırlanacak GeoGebra ekinkilerinde öğreticilere yol göstermesi açısından enstrümantal orkestrasyon boyutlarına ışık tutan tartışmalar sunmaktadır. Çalışmada kalkülüs eğitimi için GeoGebra programından nasıl yararlanılacağı ve etkinliklerin enstrümantal orkestrasyon türleri ile nasıl zenginleştirilebileceği üzerinde durulmaktadır. Çalışma kapsamında önerilen etkinlikler etkinlik tasarım parametreleri ve enstrümantal orkestrasyon türleri ile birlikte ele alınarak düzenlenmiştir. Özellikle COVID-19 Pandemi süreciyle birlikte uzaktan eğitim formatının genişleyen ağında öğrenenlerin ders ve çalışma motivasyonlarının teknoloji destekli etkinliklerle artırılması beklenmektedir. Uygulamalı ve mesleğe dönük yönü itibariyle kalkülüs derslerinde kullanılabilecek matematiksel simülasyonlarla ders süreçlerinin zenginleştirilebileceği ve öğrenenlerin kavramsal gelişimlerinin beslenebileceği, bu deneyimin gerçek hayat becerilerine yansıtılabileceği düşünülmektedir.
HDAC Inhibitor Titration of Transcription and Axolotl Tail Regeneration
Authors: Voss S. Randal , Smith Jeramiah J. , Cecil Raissa F. , Kabangu Mirindi , Duerr Timothy J. , Monaghan James R. , Timoshevskaya Nataliya , Ponomareva Larissa V. , Thorson Jon S. , Veliz-Cuba Alan , Murrugarra David
Published: December 2021

New patterns of gene expression are enacted and regulated during tissue regeneration. Histone deacetylases (HDACs) regulate gene expression by removing acetylated lysine residues from histones and proteins that function directly or indirectly in transcriptional regulation. Previously we showed that romidepsin, an FDA-approved HDAC inhibitor, potently blocks axolotl embryo tail regeneration by altering initial transcriptional responses to injury. Here, we report on the concentration-dependent effect of romidepsin on transcription and regeneration outcome, introducing an experimental and conceptual framework for investigating small molecule mechanisms of action. A range of romidepsin concentrations (0–10 μM) were administered from 0 to 6 or 0 to 12 h post amputation (HPA) and distal tail tip tissue was collected for gene expression analysis. Above a threshold concentration, romidepsin potently inhibited regeneration. Sigmoidal and biphasic transcription response curve modeling identified genes with inflection points aligning to the threshold concentration defining regenerative failure verses success. Regeneration inhibitory concentrations of romidepsin increased and decreased the expression of key genes. Genes that associate with oxidative stress, negative regulation of cell signaling, negative regulation of cell cycle progression, and cellular differentiation were increased, while genes that are typically up-regulated during appendage regeneration were decreased, including genes expressed by fibroblast-like progenitor cells. Using single-nuclei RNA-Seq at 6 HPA, we found that key genes were altered by romidepin in the same direction across multiple cell types. Our results implicate HDAC activity as a transcriptional mechanism that operates across cell types to regulate the alternative expression of genes that associate with regenerative success versus failure outcomes.
Upregulation of T Cell Receptor Signaling Pathway Components in Gestational Diabetes Mellitus Patients: Joint Analysis of mRNA and circRNA Expression Profiles
Authors: Chen Yan-ming , Zhu Qiong , Cai Jie , Zhao Zhi-jia , Yao Bin-bin , Zhou Li-ming , Ji Lin-dan , Xu Jin
Published: January 2022

Objective

Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy, and its pathogenesis is still unclear. Studies have shown that circular RNAs (circRNAs) can regulate blood glucose levels by targeting mRNAs, but the role of circRNAs in GDM is still unknown. Therefore, a joint microarray analysis of circRNAs and their target mRNAs in GDM patients and healthy pregnant women was carried out.

Methods

In this study, microarray analyses of mRNA and circRNA in 6 GDM patients and 6 healthy controls were conducted to identify the differentially expressed mRNA and circRNA in GDM patients, and some of the discovered mRNAs and circRNAs were further validated in additional 56 samples by quantitative realtime PCR (qRT-PCR) and droplet digital PCR (ddPCR).

Results

Gene ontology and pathway analyses showed that the differentially expressed genes were significantly enriched in T cell immune-related pathways. Cross matching of the differentially expressed mRNAs and circRNAs in the top 10 KEGG pathways identified 4 genes (CBLB, ITPR3, NFKBIA, and ICAM1) and 4 corresponding circRNAs (circ-CBLB, circ-ITPR3, circ-NFKBIA, and circ-ICAM1), and these candidates were subsequently verified in larger samples. These differentially expressed circRNAs and their linear transcript mRNAs were all related to the T cell receptor signaling pathway, and PCR results confirmed the initial microarray results. Moreover, circRNA/miRNA/mRNA interactions and circRNA-binding proteins were predicted, and circ-CBLB, circ-ITPR3, and circ-ICAM1 may serve as GDM-related miRNA sponges and regulate the expression of CBLB, ITPR3, NFKBIA, and ICAM1 in cellular immune pathways.

Conclusion

Upregulation of T cell receptor signaling pathway components may represent the major pathological mechanism underlying GDM, thus providing a potential approach for the prevention and treatment of GDM.
Toward a Fundamental Understanding of the Role of Lignin in the Biorefinery Process
Authors: Yao Lan , Yang Haitao , Meng Xianzhi , Ragauskas Arthur J.
Published: January 2022

As one of the main components in biomass, lignin plays a vital role in the biorefinery industry. Its unique structural feature increases the dose of cellulases during enzymatic deconstruction and is an attractive resource for many high valued products. The inhibition of lignin on cellulases is proposed to occur in several ways, with the most studied being nonproductive enzyme binding, which is attributed to hydrogen bonding, hydrophobic and/or electrostatic interactions. This review provides a comprehensive review of how lignin is transformed during various pretreatment methods as well as how these changes impact the cellulases inhibition. Future pretreatment directions for decreased cellulases inhibition are also proposed.
Genomic Insights Into the Population History and Biological Adaptation of Southwestern Chinese Hmong–Mien People
Authors: Liu Yan , Xie Jie , Wang Mengge , Liu Changhui , Zhu Jingrong , Zou Xing , Li Wenshan , Wang Lin , Leng Cuo , Xu Quyi , Yeh Hui-Yuan , Wang Chuan-Chao , Wen Xiaohong , Liu Chao , He Guanglin
Published: January 2022

Hmong–Mien (HM) -speaking populations, widely distributed in South China, the north of Thailand, Laos, and Vietnam, have experienced different settlement environments, dietary habits, and pathogenic exposure. However, their specific biological adaptation remained largely uncharacterized, which is important in the population evolutionary genetics and Trans-Omics for regional Precision Medicine. Besides, the origin and genetic diversity of HM people and their phylogenetic relationship with surrounding modern and ancient populations are also unknown. Here, we reported genome-wide SNPs in 52 representative Miao people and combined them with 144 HM people from 13 geographically representative populations to characterize the full genetic admixture and adaptive landscape of HM speakers. We found that obvious genetic substructures existed in geographically different HM populations; one localized in the HM clines, and others possessed affinity with Han Chinese. We also identified one new ancestral lineage specifically existed in HM people, which spatially distributed from Sichuan and Guizhou in the north to Thailand in the south. The sharing patterns of the newly identified homogenous ancestry component combined the estimated admixture times via the decay of linkage disequilibrium and haplotype sharing in GLOBETROTTER suggested that the modern HM-speaking populations originated from Southwest China and migrated southward in the historic period, which is consistent with the reconstructed phenomena of linguistic and archeological documents. Additionally, we identified specific adaptive signatures associated with several important human nervous system biological functions. Our pilot work emphasized the importance of anthropologically informed sampling and deeply genetic structure reconstruction via whole-genome sequencing in the next step in the deep Chinese Population Genomic Diversity Project (CPGDP), especially in the regions with rich ethnolinguistic diversity.
Lower Body Temperature Independently Predicts Delayed Cerebral Infarction in the Elderly With Ruptured Intracranial Aneurysm
Authors: Lin Hui , Wang Haojie , Xu Yawen , Lin Zhangya , Kang Dezhi , Zheng Shufa , Yao Peisen
Published: January 2022

Purpose: To assess the correlation between admission body temperature and delayed cerebral infarction in elderly patients with ruptured intracranial aneurysm (IA).

Methods: Patients with ruptured IA diagnosed between 2012 and 2020 were retrospectively analyzed. Patients were divided into a non-infarction and an infarction group based on the presence of cerebral infarction after treatment. The demographic and clinical information of the patients was gathered. Outcomes at the 3-month follow-up were assessed using the modified Rankin Scale. Correlation between admission body temperature and cerebral infarction was assessed using Spearman's rank correlation coefficient. A receiver operating characteristic (ROC) curve was used to assess the specificity and sensitivity of admission body temperature to predict cerebral infarction.

Results: A total of 426 patients (142 men and 284 women) with ruptured IA were enrolled. Elderly patients with cerebral infarction (12.4%) had a lower body temperature at admission (p < 0.001), higher prevalence of hypertension and diabetes (p = 0.051 and p = 0.092, respectively), and higher rate of poor outcomes (p < 0.001). Admission body temperature was independently associated with cerebral infarction (odds ratio [OR] = 5.469, p < 0.001); however, hypertension (OR = 0.542, p = 0.056), diabetes (OR = 0.750, p = 0.465), and aneurysm size (OR = 0.959, p = 0.060) showed no association. An inverse correlation between admission body temperature and the incidence of cerebral infarction was observed (Spearman's r =−0.195, p < 0.001). An admission body temperature of 36.6°C was able to distinguish infarction and non-infarction patients. The area under the ROC curve was 0.669 (specificity, 64.15%; sensitivity, 81.50%; p < 0.001).

Conclusions: Lower body temperature at admission (≤36.6°C) is an independent predictor of delayed cerebral infarction in elderly patients who have undergone treatment for ruptured IA. Therefore, it could be a risk factor for adverse outcomes of IA.
Nutritional Status and Body Composition in Wilson Disease: A Cross-Sectional Study From China
Authors: Geng Hao , Wang Shijing , Jin Yan , Cheng Nan , Song Bin , Shu Shan , Li Bo , Han Yongsheng , Han Yongzhu , Gao Lishen , Ding Zenghui , Xu Yang , Wang Xun , Ma Zuchang , Sun Yining
Published: December 2021

Background: Abnormal nutritional status is frequently seen in patients with chronic diseases. To date, no study has investigated the detailed characteristics of abnormal nutritional status among Wilson's disease (WD) patients in the Chinese cohort. This study aimed to describe the nutritional status of WD patients, with a particular focus on the differences between patients with different phenotypes.

Methods: The study subjects comprised 119 healthy controls, 129 inpatients (hepatic subtype, n = 34; neurological subtype, n = 95) who were being treated at the affiliated hospital of the Institute of Neurology, Anhui University of Chinese Medicine. All of the subjects were assessed for body composition by using bioelectrical impedance analysis. All WD patients received anthropometry, nutritional risk screening 2002 (NRS2002), and laboratory test (hemocyte and serum biomarkers) additionally.

Results: Compared with healthy controls, the fat mass and rate of total body and trunk were significantly higher in WD patients (P < 0.001), the muscle and skeletal muscle mass of total body and trunk were significantly lower in WD patients (P < 0.001). Compared with hepatic subtype patients, the fat mass and rate of total body, trunk, and limbs were significantly lower in neurological subtype patients (P<0.01); while there were no significant differences in muscle and skeletal muscle between these two subtypes. The overall prevalence of abnormal nutritional status in WD patients was 43.41% (56/129). The prevalence of high-nutritional risk and overweight in WD patients was 17.83% (23 of 129) and 25.58% (33 of 129), respectively. Compare with patients with high nutritional risk, macro platelet ratio, alkaline phosphatase, the basal metabolic rate (p < 0.05), creatinine, trunk fat rate (p < 0.01) and appendicular skeletal muscle mass (p < 0.001) were significantly higher in patients without nutritional risk (p < 0.001). Patients with a high nutritional risk tend to have a lower cholinesterase concentration (x2 = 4.227, p < 0.05).

Conclusion: Both patients with H-subtype and N-subtype are prone to have an abnormal nutritional status. Longitudinal studies are required to investigate if nutritional status and body composition could reflect prognosis in WD patients, and which of these body composition indexes contribute to malnutrition and worse prognosis.
Assessing the Effect of Board Gender Diversity on CSR Reporting Through Moderating Role of Political Connections in Chinese Listed Firms
Authors: Shaheen Riffat , Yang Hailan , Bhutto Muhammad Yaseen , Bala Hussaini , Khan Fahad Najeeb
Published: December 2021

This study departs from existing work on board gender diversity (BGD) and corporate social responsibility (CSR) reporting by analyzing and explaining the mechanism by which gender-diverse boards in politically embedded firms (PEFs) affect firms’ CSR reporting choices in a unique institutional setting of Chinese listed firms from 2010 to 2018. The following main results are obtained. First, having female directors and executives with political connections (PCs) on corporate boards improves the CSR reporting of firms. Firms with PCs have a greater possibility to issue CSR reports than their non-connected counterparts. Second, firms that have both gender diversity and PCs on their boards of directors are more likely to engage in CSR reporting. There is an indication that the presence of PCs on boards can strengthen the effect of female directors on firms’ CSR reporting. Third, the presence of female directors on corporate boards has a stronger relationship with CSR reporting in PEFs than in non-PEFs. The study concludes that both BGD and PCs on corporate boards positively influence the diffusion of CSR-related practices in the Chinese business environment.
Relationship Between Postnatal Depression of Mental Health Patients and the Psychological Health of Their Offspring
Authors: Abd Rahman Fairuz Nazri , Wong Yun Yaw , Khalib Ahmad Qabil
Published: January 2022

Postnatal depression is a major illness affecting maternal and family health. The rate of postnatal depression among mental health clients is postulated to be higher than in the community due to the added brain assault. Children of parents who are mental health clients are more likely to have psychological problems compared to children from other parents in the community. This study investigates the rate of postnatal depression among mental health clients and their offspring's psychological health. A total of 140 mental health clients were assessed using the Edinburgh Postnatal Depression Scale (EPDS). They subsequently completed the Strength and Difficulties Questionnaire (SDQ) regarding their children. The majority ethnicity was the Kadazan (40.7%). The mean age of mothers was 38.6 (7) years with most having a secondary education (53.6%) and a household income per month of < RM1000 per month (27.1%). The postnatal depression rate was 47.8%. Higher EPDS scores were associated with higher total SDQ scores in their offspring. Model 1 was unadjusted, giving an OR of 5.65 [95% CI (3.74, 7.55)], p < 0.001. After adjustment for confounders, Model 2 had an OR of 5.51 [95% CI (3.57, 7.46)], p < 0.001. More efforts need to be given to the early detection of maternal depression and its prompt treatment in mental health clients because of the relationship with the psychological health of the offspring.