bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety of HIF Prolyl-Hydroxylase Inhibitors for Anemia in Dialysis Patients: A Systematic Review and Network Meta-Analysis
Authors: Chen Dinghua , Niu Yue , Liu Fei , Yang Yue , Wang Xue , Li Ping , Chen Xiangmei
Published: December 2022

Aim: We performed a systematic review and network meta-analysis,
evaluating the safety and efficacy of Hypoxia-inducible factor prolyl
hydroxylase inhibitors (HIF-PHIs) among dialysis chronic kidney disease
(CKD) patients. Methods: Safety was evaluated with any adverse events
(AEs), serious adverse events (SAEs), and twelve common events. Efficacy
was mainly analyzed with hemoglobin (Hb) response. All reported results
were summarized using mean difference (MD) and risk ratio (RR) with 95%
confidence interval (CI). Publication bias was assessed through funnel
plots. Results: Twenty trials with 14,947 participants were included,
comparing six HIF-PHIs with Erythropoiesis-stimulating agents (ESAs). No
significant differences were indicated in AEs and SAEs between each
HIF-PHI and ESA. The occurrence of gastrointestinal disorder was higher
in Enarodustat and Roxadustat than in ESAs (RR: 6.92, 95% CI:
1.52-31.40, p=0.01; RR: 1.30, 95% CI: 1.04-1.61, P=0.02). The
occurrence of hypertension was lower in Vadadustat than in ESAs (RR:
0.81, 95% CI: 0.69-0.96, p=0.01). The occurrence of vascular-access
complications was higher in Roxadustat (RR: 1.15, 95% CI: 1.04-1.27,
p＜0.01) while lower in Daprodustat (RR: 0.78, 95% CI: 0.66-0.92,
p＜0.01) than in ESAs. In the risk of the other nine events, including
cardiovascular events, no significant differences were observed between
HIF-PHIs and ESAs. For efficacy, network meta-analysis showed that the
overall performance was similar to ESAs. Conclusion: Although HIF-PHIs
did not show significant differences from ESAs in terms of overall AEs
and SAEs, statistical differences in gastrointestinal disorder,
hypertension, and vascular-access complications were observed between
HIF-PHIs, which deserved to be noted in clinical decision-making.
Existence of traveling wave front for a generalized reaction-convection-diffusion equation
Authors: Wei Minzhi , Dai Yanfei
Published: December 2022

In presented paper, the existence of traveling wave front for a
generalized reaction-convection-diffusion equation with different delay
convolution kernels is investigated by using the geometric singular
perturbation theory. Firstly, we shall show that such traveling wave
front exists without delay by qualitative analysis. After that, for the
generalized reaction-convection-diffusion equation with a special local
strong delay convolution kernel, the desired heteroclinic orbit is
obtained by constructing a locally invariant manifold. Finally, with a
nonlocal weak generic delay, the existence of traveling wave front is
proved by implicit function theorem and Fredholm theory.
Coronary microcirculation and left ventricular diastolic function but not myocardial deformation indices are impaired early in patients with chronic kidney disease
Authors: Bechlioulis Aris , Lakkas Lampros , Naka Katerina , Duni Annila , Gouva Chariklia , Balafa Olga , Koutlas Vasileios , Katsouras Christos , Dounousi Evangelia , Michalis Lampros
Published: December 2022

Aim. To investigate abnormalities in myocardial strain and
classic echocardiographic indices and coronary flow reserve (CFR), in
younger vs older CKD patients. Methods. Sixty consecutive CKD
patients (<60 years old n=30, ≥60 years old n=30) and 30
healthy controls (age- and gender-matched with younger CKD patients)
were recruited. An echocardiographic assessment including myocardial
strain indices was performed at baseline and following dipyridamole
administration in all participants. Results. Younger CKD
patients had higher E/e’, left ventricular mass index and relative wall
thickness and lower E’ (p<0.005 for all) compared to healthy
controls. Older CKD patients had lower E/A and E’ (p<0.05 for
both) compared to younger CKD patients; these differences did not remain
significant after adjustment for age. CFR was higher in healthy controls
compared to younger and older CKD patients (p<0.05 for both)
without a significant difference between CKD groups.
Dipyridamole-induced changes did not differ significantly among the 3
groups. Conclusions. Compared to healthy controls, impaired
coronary microcirculation and left ventricular diastolic function, but
not myocardial strain abnormalities, are found in young CKD patients and
deteriorate with aging.
ELEVATED ADIPOCYTE MEMBRANE PHOSPHOLIPID SATURATION DOES NOT COMPROMISE INSULIN SIGNALING
Authors: Palmgren Henrik , Petkevicius Kasparas , Bartesaghi Stefano , Ahnmark Andrea , Ruiz Mario , Nilsson Ralf , Löfgren Lars , Glover Matthew S. , Andréasson Anne-Christine , Andersson Liselotte , Becquart Cécile , Kurczy Michael , Kull Bengt , Wallin Simonetta , Karlsson Daniel , Hess Sonja , Maresca Marcello , Bohlooly-Y Mohammad , Peng Xiao-Rong , Pilon Marc
Published: December 2022

Increased saturated fatty acid levels in membrane phospholipids have been implicated in the development of metabolic disease. Here, we tested the hypothesis that increased saturated fatty acid (SFA) content in cell membranes negatively impacts adipocyte insulin signaling. Pre-adipocyte cell models with elevated SFA levels in phospholipids were generated by disrupting the ADIPOR2 locus, which resulted in a striking two-fold increase in SFA-containing phosphatidylcholines and phosphatidylethanolamines, which persisted in differentiated adipocytes. Similar changes in phospholipid composition were observed in white adipose tissues isolated from the ADIPOR2 knockout mice. The SFA levels in phospholipids could be further increased by treating ADIPOR2-deficient cells with palmitic acid and resulted in reduced membrane fluidity and endoplasmic reticulum stress in mouse and human pre-adipocytes. Strikingly, increased SFA levels in differentiated adipocyte phospholipids had no effect on adipocyte gene expression or insulin signaling in vitro. Similarly, increased adipocyte phospholipid saturation did not impair white adipose tissue function in vivo, even in mice fed a high saturated fat diet at thermoneutrality. We conclude that increasing SFA levels in adipocyte phospholipids is well tolerated and does not affect adipocyte insulin signaling in vitro and in vivo.
Numerical Analysis of Variable Morphing Wing for Improved Aerodynamic Performance of a Predator MQ-1B
Authors: Kaygan Erdogan
Published: December 2022

In this paper, aerodynamic performance benefits of morphing unmanned aerial vehicle’s wing concepts are investigated. A Predator MQ-1B with variable wing structure was utilized for this study. The concept consists of variable twist (-10°< θ <10°, in steps of ±2.5°) and wing sweep (0°< θ <30°, in steps of +10°) to illustrate morphing wing’s performance benefits. All computations were performed with Athena Vortex Lattice modelling with varying degrees of twist and sweep angle considered. The results obtained from this work show that if morphing wings adapted to the Predator MQ-1B, it will provide significant performance benefits and also offer a great opportunity to reduce fuel consumption.
Prediction of pulmonary complications following spine surgery: The ASA and ARISCAT risk indexes
Authors: Balkaya Ayşe Neslihan , Demirel Asiye
Published: December 2022

Objective: We aimed to evaluate the effectiveness of predicting postoperative pulmonary complications (PPCs) following spine surgery, comparing American Society of Anesthesiologist (ASA) and Assess Respiratory Risk in Surgical Patients in Catalonia (ARISCAT) risk scoring systems.

Material and methods: We reviewed 377 patients aged≥18 years who had undergone vertebral surgery. Demographic data, comorbidities, ASA classification, body mass index, ARISCAT risk score, pulmonary complications developing with in the postoperative 1st month were assessed.

Results: A total of 377 patients, 221 (58.6%) women and 156 (41.4%) men, mean age of 59±11.8 years were evaluated. Out of the 377 patients, 73 (19.4%) patients were ASA I, 235 (62.3%) patients were ASA II, 69 (18.3%) patients were ASA III, and the mean ARISCAT score was 22.51±8.38. In the postoperative period, PPC was identified in 30 (8%) patients, with atelectasis in 15 (4%), pneumothorax in 4 (1.1%), pneumonia in 4 (1.1%), respiratory failure in 4 (1.1%), bronchospasm in 2 (0.5%) patients, and pulmonary embolism in 1 (0.3%) patient. There was a statistically significant correlation between the presence of PPC and ASA score, and between the presence of PPC and the ARISCAT levels (p=0.000, p=0.000). The incidence of PPC increased with increasing ASA scores. The ARISCAT scores were higher in patients who developed PPC. The hospital stay of patients with PPCs were longer than other patients (p=0.000).

Conclusion: In our study, in which ASA classification and ARISCAT risk index were compared as a means to predict PPC, both scores were found to be effective.
Clinical management of cementifying fibroma: A case report and pertinent review of the current literature
Authors: Tayşi Aysegul Erten , Taysi Mert , Yurdabakan Zuhal , Aksakallı Fatma Nihan , Olgac Vakur
Published: December 2022

Cementifying fibroma is an uncommon neoplasm composed by varying amounts of cementum, bone and fibrous tissue. As a results of having similar histolological features based on inactive-looking odontogenic epithelium embedded in a fibrous stroma, it is often hard to differentiate from other fibro-osseous lesions such as fibrous dyplasia and calcifying odontogenic tumor. At this point, it is undoubtedly clear that proper radiological and clinical diagnosis play a great role together in identification. We present a rare case of this entity along with a number of clinical and radiographic features that set it apart from other pathologies mimicking fibro-osseous lesions.
The factors affecting occurrence of urethral stricture after transurethral resection of the prostate
Authors: Durmus Emrullah , Ok Fesih , Sert İbrahim Ünal
Published: December 2022

Objectives: Urethral stricture is one of the complex subjects of urology in terms of high recurrence rates, patient care, treatment difficulties and follow-up. We aimed to evaluate factors associated with the occurrence of urethral stricture after TUR-P (Transurethral resection of the prostate) surgery.

Material and methods: In our clinic, 301 patients who underwent TUR-P surgery for benign prostatic hyperplasia (BPH) were analyzed retrospectively. The patients who developed urethral stricture after TUR-P were named Group-1, did not develop were named Group-2. In addition, the patients were compared in terms of demographic and perioperative data. 

Results: Urethral stricture was observed in 21 (6.97%) of the patients and not in 280 (93.03%) of them. There was no significant difference between the two groups in terms of age (p=0.913), resectoscope size (p=0.932), energy source type (p=0.932), energy source power (p=0.838), urethral catheter type (p=0.776), urethral catheter size (p=0.973), urethral catheter duration (p=0.797) and urethral catheter traction (p=0.887). Resection time was significantly higher in patients with urethral stricture (53.1±10.8 min vs. 42.2±9.7 min, p<0.001). The preoperative urinary tract infection (UTI) rate was significantly higher in patients with urethral stricture. (76.2% vs 40.0%, p=0.001). The optimum cut-off value for resection time associated with the risk of urethral stricture after TUR-P was 38.5 minutes, with an AUC of 0.812 (95% CI 0.738–0.885).

Conclusion: Prolonged resection time and even if treated, preoperative UTI increases the risk of urethral stricture after TUR-P surgery. However, if the resection time is not long, patients are more protected from developing urethral stricture.
Preparation of the surgical place for laparoscopic procedure of the prostate gland tumors
Authors: Umurzakov Khussan , Kaydarova Dilyara , Shalgumbayeva Gulnar , Khaitmat Atkhamzhan , Sagidullin Sayan , Ibraev Askar
Published: December 2022

Aim: The purpose of this study to present the upgrading method of laparoscopic procedure of prostate cancer.

Material and methods: This work was made as part of the PhD dissertation. This technique could be recommended for treatment of the prostate gland tumors. The Patent of the Republic of Kazakhstan №35437 was received on 31.12.2021   

Results: The laparoscopic procedure for both methods are the same, there is some upgrading of traditional method by proposing improvements of trocars insertion. During traditional method four working trocars are installed extraperitoneal under the control of optics. We recommend four working trocars are installed under the control of the index finger, palpating the lower epigastric vessels from the inside; it is avoid to damage of the peritoneum, injection of gas into the abdominal space, damage of the vessels of the pelvis.

Conclusion: The method allows avoiding bleeding, pneumoperitoneum, and decreased saturation; and in the early postoperative period, peritonitis is excluded and the late postoperative period, adhesive processes do not occur.
Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study
Authors: Abilbayeva Arailym , Tarabayeva Anel , Idrisova Gulzhana , Abdrakhmanova Aigul , Sadykova Ainur , Yegemberdiyeva Ravilya , Duisenova Amangul
Published: December 2022

Objective: To investigate the prevalence of diabetes mellitus in comorbidity structures and its effect on the clinical course in hospitalized COVID-19 patients in south region of Kazakhstan.

Material and methods: A retrospective analysis of data from 918 patients with COVID-19 treated at the City Clinical Infectious Diseases Hospital was carried out. Pearson's Chi-square test and Student's t-test were conducted.

Results: In Kazakhstan, diabetes mellitus occupies the second position in the structure of comorbidities in patients with COVID-19 with a share of 20%. Diabetes mellitus in patients most often occurs in combination with cardiovascular diseases and arterial hypertension (20.3% and 16.3%, respectively). Combination of diabetes mellitus, arterial hypertension and other diseases was detected in 72.4% of patients. Combination of diabetes mellitus, cardiovascular and other diseases was detected in 32.5%.

In diabetes mellitus patients, COVID-19 was more severe, the hospital stay was longer, and patients over 60 years of age suffered. These patients had a combination of diabetes mellitus with arterial hypertension, obesity, and cardiovascular diseases. Hyperglycemia, elevated blood pressure, rapid breathing, and low saturation were more common for these patients.

Conclusion: Diabetes mellitus ranks second in the structure of comorbidities in COVID-19 in the south region of Kazakhstan and is characterized by a combination with cardiovascular diseases, arterial hypertension and obesity. In patients with diabetes, COVID-19 is more severe, which affects the length of stay in the hospital, the mortality rate and the need for transfer to the Intensive Care Unit.
THE IMPACT OF COMBINING FOLLOW-UP QUESTIONS AND WORKED EXAMPLES IN PROGRAM VISUALIZATION TOOL ON IMPROVING STUDENTS’ HELD MENTAL MODELS OF POINTERS’ VALUE AND ADDRESS ASSIGNMENT
Authors: Adam Basigie Mtakho,
Published: December 2022

Previous studies have shown that the lack of a useful mental model of pointers is one of the reasons why many novice programmers fail the data structures course. This study had two main objectives: to analyze the status of mental models of pointers (focusing on value and address assignment); and to evaluate the impact of combining worked-examples and follow-up questions in CeliotM program visualization (PV) tool in the learning of pointers. The subjects of the study were sixty-two second-year undergraduate students taking a course on data structures (PMT 221) at the College of Natural and Mathematical Sciences (CNMS) of the University of Dodoma. Data were collected using pretest and posttest questionnaires. The collected data were analyzed using descriptive statistics. The results showed that 56.5% of the students had incorrect mental models of pointers. The results also showed that using the proposed strategy improved the students’ mental models of pointers from 56.5% to 87.1%. These results contribute to our understanding of the most common misconceptions that novice students may have when learning pointers. The findings of this study confirm previous studies that when the new innovative teaching strategies are used in combination with PV tools in teaching and learning programming can help improve students’ programming comprehension.
SOCIOCULTURAL ADAPTATION OF INTERNATIONAL STUDENTS FROM NEIGHBORING AND DISTANT COUNTRIES: INTEGRATING ANALYTICAL CONTEXTS
Authors: Tamara Vasil'evna Chernikova, , Eduard Aleksandrovich Sokalskiy, , Valentina Viktorovna Boluchevskaya, , Olga Igorevna Shutova,
Published: December 2022

This article presents a comparative study of the sociocultural adaptation of international students coming to Russia from neighboring (former Soviet republics) and distant countries and studying at the universities of the South Russian region. The preliminary overview of the studies reflects the different contexts in which the problem of adaptation is studied: economic, political, ethno-cultural-differential, and socio-identitarian. It is noted that the Russian approach to the organization of the educational process in groups of international students is characterized by its integrative nature. The implementation of educational tasks includes communicative opportunities for adaptation. This increases the well-being of international students in everyday life. At the same time, concern for the quality of the educational process and advanced teaching technologies affects the prestige and, consequently, the economic competitiveness of the university and the international status of Russian higher education. The study of various aspects of international students’ adaptation – psychological (resources) and sociocultural (expression) – was conducted on a group of 397 individuals, mainly from countries with Eastern culture, 247 men and 150 women. Among them, 110 were from distant countries, and 287 were from neighboring countries. We used an express diagnosis method developed based on an adapted version of the method “Self-assessment of psychological adaptability” by A.L. Svensitsky and the scales “Social commitment to the country” and “Cultural commitment to the country” from the questionnaire by S.V. Frolova. Spearman rank correlation coefficient was used for statistical analysis of the obtained data. The psychological and sociocultural adaptation of respondents from both subgroups showed a similar correlation between adaptation resources and their expressions at p 0.01. At the same time, significant differences between the samples were found in the indicators. The students who came to study from distant countries (Asian and African countries) showed low psychological (active and communicative) potential for successful sociocultural adaptation, while they had high expectations for successful adaptation. Improving their adaptation potential through educational means can be achieved by combining academic work with problem-solving activities in the educational, vocational, social, and communication domains. Students from neighboring countries (former Soviet republics) based their claims of successful adaptation on the social ties between the countries but simultaneously showed a distance from Russian cultural values. In this case, the work of educators would be effective if they continued to develop positive dynamics for intercultural relations and incorporate the traditions of interethnic good neighborliness on the territory of the southern region of Russia.
REHABILITATING J. L. ROMANY’S SOCIAL HOUSING IN THE 21ST CENTURY
Authors:   Polytechnic University of Madrid, Sánchez-Torija Jorge Gallego , Fernández Nieto María Antonia ,   Polytechnic School, Architecture. Francisco de Vitoria University, Herrero Jesús García ,   Polytechnic University of Madrid
Published: December 2022

Introduction: The modern heritage of 20th century Spanish architecture, particularly in the city of Madrid, includes an extensive range of high-quality social housing that, due to its peripheral location and economic restrictions, can be lost without public policies to preserve it. Updating this housing to meet the current habitability requirements, as well as enhancing and transforming it into high-quality 21st century residential buildings, is a task that cannot be postponed. Purpose of the study: The issues of energy efficiency, habitability and accessibility are very salient today, so it seems pertinent to recover relevant examples of 20th century architecture and investigate to what extent the parameters with which they were designed are still valid. Methods: This paper reviews housing case studies in two neighborhoods, Poblado Dirigido de Fuencarral and Colonia Juan XXIII de Carabanchel, comprehensively analyzing the original buildings and their current rehabilitation. This includes comparing the buildings’ energy efficiency before and after the intervention carried out. Approach: This study verified that in both cases, an attempt was made to recover several elements of the original design during rehabilitation. Results: We found that both projects were originally committed to creating an open, pedestrian-friendly city with abundant vegetation, which is still a valid value today. Despite the economic restrictions at the time of construction, both projects used advanced energy strategies, such as the passive design offered by cross ventilation, the unusual thermal insulation envelope, or the efficient district heating. Novelty: In addition, this paper aims to incorporate the heritage of the great mid-20th century architect José Luis Romany, author of both projects, into modern Spanish architecture.
DETERMINING VISCOELASTIC CHARACTERISTICS OF THE ELEMENTS OF MULTI-LAYER STRUCTURES BASED ON ENERGY DISSIPATION ANALYSIS
Authors:   Don State Technical University, Tiraturyan Artem , Uglova Evgeniya ,   Don State Technical University, Akulov Vladimir ,   Don State Technical University
Published: December 2022

The deteriorating operating conditions of roads is one of the most important problems facing specialists in the road industry. It is mainly associated with a reduction in the rigidity of road pavements made as extended multi-layer structures. To identify the causes of rigidity reduction, non-destructive testing is used, which is based on solving the inverse coefficient problem of restoring the elastic constants based on the response on the surface. Purpose of the study: We aimed to provide a rationale for a new pavement condition indicator that would take into account the history of deformation and loading from a source on the surface, based on which it would be possible to solve the inverse problem of restoring the elastic and viscous characteristics of pavement layers. Methods: To do that, we performed mathematical modeling of the stress-strain state of a multi-layer medium based on the solution of a system of dynamic Lame equations. Viscosity is taken into account by introducing tangents of the angles of wave energy losses in the materials of layers. Results: The results obtained in modeling for the first time made it possible to establish the relationship between changes in the modulus of elasticity as well as tangents of the angles of energy losses in pavement layers and the amount of energy dissipation in the structure. Discussion: It should be noted that it is possible to switch from the bowl of maximum dynamic deflections as the main pavement condition indicator to the analysis of hysteresis loops on the road structure surface, recorded at different distances from the point of load application and being an analogue of the full bowl of dynamic deflections showing the history of the test object loading.
Markov Modelling for Mucoviscidosis using Genomic Data
Authors: David Packia Muthu Jeniffer , Kaliyaperumal Senthamarai Kannan
Published: December 2022

The CFTR gene, which encodes a protein present in the cell membranes of epithelial tissues, has an effect on a number of organ systems in the human body. Mutations in the CFTR gene lead to incorrect regulation of cell electrolytes and water levels. The importance of this gene for typical human development has been clearly stated through studies on the CFTR mutation. A new born that inherits one mutant copy of the CFTR gene from each parent may have cystic fibrosis, which is an autosomal recessive disease. This paper establishes a model for mutant genes that will assist in determining whether or not the embedded gene is mutated. Early detection enables the possibility of slightly earlier disease risk reduction. Modelling mutant genes and correspondingly matching the new gene with them would be a crucial and cost-effective method of preventing various chronic diseases and treatment resistance.
Pterygium Surgery: Autologous Blood or Suture for Conjunctival Autografting?
Authors: Akioud Wafae , Hamzi Abderrahmane , Khamaily Mehdi , Mozarie Yassine , Oubaaz Abdelbare
Published: December 2022

Purpose: The aim of our study is to compare two different techniques for conjunctival autografting: surgical suturing and autologous blood coagulum.

Methods: In this prospective study, we randomly divided 30 patients with primary pterygium into two groups similar in matter of age and sexe distribution. Group 1 underwent surgical suturing for conjunctival autografting and Group2 underwent sutureless autologous blood coagulum for that matter. We evaluated the primary outcome in terms of operative time, patients’ discomfort, graft displacement, graft failure and recurrences. The follow-up rate was at day1, week 1, month 1, 3 months and 6 months.

Results: The operative time and patients’ discomfort were considerably reduced using the blood coagulum method (Operative time :15±3 minutes for Group 2 versus 32±2 minutes for Group1) (Patients discomfort p value <0.001). The graft failure and displacement were, however, higher in Group 2 compared to the first Group (p value for both is <0.001). The recurrence rate was equal in both groups.

Conclusion: The use of autologous blood coagulum for conjunctival autografting is less time consuming and more comfortable for patients. However, the graft failure and displacement are more common with this technique.
Optic Neuropathy Induced by Sildenafil: When Blinded by Pleasure: Case Report and Literature Review)
Authors: Akioud Wafae , Hamzi Abderrahmane , Khamaily Mehdi , Mozari Yassine , Oubaaz Abdelbare
Published: December 2022

Sildenafil citrate is phosphodiesterase 5 inhibitor (PDE5i) that is widely used to treat male erectile dysfunction. However, this molecule has been associated with many visual side effects which most are transient but some can lead to persistent vision loss. Non arteritic anterior ischemic neuropathy (NAION) has been reported in some cases as a very rare, but possible, Sildenafil citrate’s visual adverse effect. We present the case of young patient under erectile dysfunction medication who developed an induced toxic neuropathy, while reviewing the other reported cases in medical literature.
Structural model equations: Analysis on the performance abilities of the main competencies of graduates
Authors: Sunanto Rahma Faelasofi , Hendrowati Tri Yuni
Published: December 2022

The purpose of this research is to find out the structural equation model (Structural Equation Model) on the perceptions of users of the graduates of the Teaching and Education Faculty (FKIP) Muhammadiyah Pringsewu University on the performance abilities of graduates' main competencies and the ability to work in teams. This research will use the Partial Least Square (PLS) method which can be used for small samples. In addition, PLS does not require the assumption that the data distribution must be normal or not. The results of this research are ethics, developing English language skills, and self-development has a positive effect on the ability to work in teams and performance skills related to the main competencies of graduates. Also, there is a positive influence from the ability to work on the main competencies, whereby increasing the ability to work will increase the main competencies of FKIP UMPRI graduates.
Hydra effects predator-prey bazykin's model with stage-structure and intraspecific for predator
Authors: Pratama Rian Ade , Amil Siddik A. Muh. , Dadi Oswaldus , Kasbawati Kasbawati
Published: December 2022

Bazykin's predator-prey population model is considered to represent the exchange stability condition of population growth. The existence of the hydra effect and, at the same time, analyzing its influence on population growth. The condition of the model divides the species into a stage structure, namely, prey, immature predators, and mature predators. The population growth of the three species has its own characteristics. This research revealed that the Holling type II and intraspecific predatory function responses together induce the Hydra effect. In the model formed, there are 12 equilibrium points, with details for every seven points of negative imaginary equilibrium and five points of non-negative equilibrium. The findings of research studies center on five points of non-negative equilibrium. All real roots that interpret the species population's growth conditions are taken and tested for long-term stability. The test results show one point of equilibrium that meets the Routh-Hurwitz criteria and their characteristic equations. In numerical simulations, the maximum sustained yield is in the local asymptotic stable state. The growth of prey trajectories increased significantly, although at the beginning of the interaction there was a slowdown in population growth. Meanwhile, the population of immature predators and mature predators was not significantly different. Both populations grow steadily toward the point of population stability. It turns out that the two populations grow inversely, the faster the rate of predation by predators, the faster the growth rate of the prey population.
Forecasting Indonesian inflation using a hybrid ARIMA-ANFIS
Authors: Fitriyati Nina , Mahmudi Mahmudi , Wijaya Madona Yunita , Maysun Maysun
Published: December 2022

This paper discusses the prediction of the inflation rate in Indonesia. The data used in this research is assumed to have both linear and non-linear components. The ARIMA model is selected to accommodate the linear component, while the ANFIS method accounts for the non-linear component in the inflation data. Thus, the model is known as the hybrid ARIMA-ANFIS model. The clustering method is performed in the ANFIS model using Fuzzy C-Mean (FMS) with a Gaussian membership function. Consider 2 to 6 clusters. The optimal number of clusters is assessed according to the minimum value of the error prediction. To evaluate the performance of the fitted hybrid ARIMA-ANFIS model, it can be compared to the classical ARIMA model and with the ordinary ANFIS model. The result reveals that the best ARIMA model for inflation prediction in Indonesia is ARIMA(2,1,0). In the hybrid ARIMA(2,1,0)-ANFIS model, two clusters are optimal. Meanwhile, the optimum number of clusters in the ordinary ANFIS model is six. The comparison of prediction accuracy confirms that the hybrid model is superior to the individual model alone of either ARIMA or ANFIS model.
Students’ mathematical representation skills in solving numeracy problems with profession context
Authors: Septiadi Dimas Danar , Yuliati Ikha , Widyastuti Rany
Published: December 2022

This research aims to describe students’ mathematical representation skills in solving numeracy problem with profession context. This is qualitative descriptive research with 12 students for its research subjects. There are four steps in analyzing the data, those are data collection, data condensation, data display, and conclusions. To check the validity, researchers used techniques triangulation. This research shows that, among those 12 subjects, there are four types of model in solving numeracy problem with profession context. Those are first, students use visual and external representation; second, they perform visual, verbal, math model, and internal representation; third, they use verbal, visual, and external representation; and fourth of all, they use verbal and external representation. To make this result fruitfull, other researchers can try to design mathematics learning activities to train students’ mathematical representation skill such that when students solve numeracy problems, they will not face any difficulties.
Sejarah Konversi Khalifah Al-Rasul Menjadi Khalifatullah
Authors: Khoiri Mif Tahul
Published: December 2022

AbstrakArtikel ini membahas sejarah konversi khalifah al-rasul menjadi khalifatullah, yang mana, dalam perjalanan sejarah Islam pasca wafatnya rasulullah, kepemimpinan dalam Islam mengalami beberapa kali pergantian. Setelah rasulullah wafat, kepemimpinan di kendalikan oleh empat sahabat nabi, yakni Abu Bakar As-Shidiq, Umar Bin Khattab, Utsman Bin Affan, dan Ali Bin Abi Tholib. Yang mana keempat sahabat ini dikenal dengan sebutan Khulafaur Rasyidin. Pasca kepemimpinan khulafaur rasyidin, kepemimpinan selanjutnya beralih ke Dinasti Umayyah yang terdiri dari empat belas pemimpin. Kemudian setelah dinasti Umayyah tumbang, munculah kepemimpinan Dinasti Abbasiyah yang dipimpin oleh 37 pemimpin. Yang mana dari munculnya dinasti abbasiyah inilah gejolak selain khalifah Abu al-Abbas al-Saffah, konversi dari khalifah al-rasul menjadi khalifatullah mulai tampak. Di akhir berdirinya dinasti abbasiyah tersebut, ketika abbasiyah mulai lemah, berdirilah dua kekhalifahan yakni, kekhalifahan Fatimiyah di Afrika Utara dan kekhalifahan Dinasti umayyah II Andalusia.Kata kunci: Sejarah, Konversi, Khalifah al-rasul, khalifatullah. AbstractThis article discusses the history of conversion of the caliph of al-rasul to khalifatullah. Which, in the course of Islamic history after the death of the apostle, leadership in Islam experienced several changes. After the Prophet's death, leadership was handled by four Companions of the Prophet, Abu Bakr As-Shidiq, Umar Bin Khattab, Utsman Bin Affan, and Ali Bin Abi Tholib. Which these four friends are known as Khulafaur Rasyidin. After the rulership of khulafaur rasyidin, the leadership then shifted to the Umayyad Dynasty consisting of fourteen leaders. Later after the Umayyad dynasty collapsed, the leadership of the Abbasid Dynasty led by 37 leaders. Which of the emergence of this abbasiyah dynasty is the turmoil besides Caliph Abu al-Abbas al-Saffah, the conversion of the caliph al-rasul to khalifatullah began to appear. At the end of the abbasiyah dynasty, when abbasiyah began to weaken, stood two caliphate namely, the Fatimid caliphate in North Africa and the Caliphate of the umayyah Dynasty of Andalusia II.Keywords: History, Conversion, Caliph al-rasul, khalifatullah.
Historiografi Islam Kesarjanaan Barat dalam Tinjauan Ortodoksi dan Heterodoksi
Authors: Majdi Ahmad Labib
Published: December 2022

Artikel ini bertujuan untuk menganalisis historiografi Islam kesarjanaan Barat dalam sudut pandang ortodoksi dan heterodoksi. Narasi dan historiografi Islam kesarjanaan Barat yang berusaha untuk didudukkan posisinya adalah karya-karya historiografi yang tergolong pada karya-karya revisionis moderat dan radikal. Untuk tujuan ini, dirumuskan konsep ortodoksi-heterodoksi dalam kajian sejarah Islam. Artikel ini termasuk ke dalam penelitian kualitatif kepustakaan dengan sifat analisis deskriptif-eksplanatif-interpretatif dan menggunakan pendekatan historis-filosofis sebagai alat bantu analisis. Temuan yang didapatkan adalah jika dilihat dari narasinya, maka karya historiografi revisionis dapat dipandang heterodoks, tetapi jika dilihat dari epistemolog-metodolog, maka dapati diposisikan sebagai ortodoks. Namun, karena dua istilah ini kadang tidak diterima begitu saja, maka artikel ini juga menawarkan kajian sejarah Islam kesarjanaan Barat yang menghasilkan historiografi Islam revisionis sebagai sebuah kajian yang ada pada tataran ortopraksi. Dengan tawaran demikian, karya historiografi Islam revisionis tidak perlu ditolak dari segi epistemologi dan metodologinya, walaupun tidak dapat diterima sepenuhnya dari sisi hasil temuan atau kesimpulan.
Tradisi Terbang Gembrung sebagai Salah Satu Sarana Penyebaran Islam di Kampung Naga
Authors: Sumawinata Shiska , Aryanti Dewi Raihan , Azzahra Maryam
Published: December 2022

AbstrakArtikel ini berisi pembahasan terkait tradisi Terbang Gembrung masyarakat Kampung Naga yang dijadikan sebagai sarana penyebaran Islam. Kampung Naga merupakan salah satu kampung adat yang berada di  Tasikmalaya, Jawa Barat. Sebagai kampung adat, masyarakat kampung Naga masih mempertahankan tradisi yang dimilikinya secara turun-temurun. Upaya mempertahankan tradisi di tengah modernisasi menjadi motivasi generasi penerus untuk mempertahankan tradisi daerahnya. Salah satu tradisi yang masih dipertahankan oleh masyarakat Kampung Naga hingga saat ini adalah Terbang Gembrung atau Terbangan. Masuknya tradisi ini ke Kampung Naga diduga memiliki hubungan erat dengan masuknya Islam ke tanah Sunda. Hal tersebut disimbolkan melalui alat musik Terbangan. Di dalam tradisi ini terdapat nyanyian berupa selawat untuk nabi yang diiringi oleh instrumen sejenis rebana atau tagonian. Di samping itu, masyarakat Kampung Naga percaya bahwa mereka merupakan keturunan Singaparna dari Kerajaan Galunggung yang memeluk agama Islam. Penulis menggunakan metode studi literatur untuk mencari dan mengumpulkan sumber-sumber yang relevan dalam menyusun artikel ini.Kata Kunci: Tradisi Terbang Gembrung, Kampung Naga, Sejarah.
Islamic Intellectual Development during the Abbasid Dynasty (750 AD-861 AD)
Authors: Hasanah Uswatun
Published: December 2022

This article analyzes the history of Islamic intellectual progress during the Abbasid Dynasty which in Islamic literature is said to be the city of Baghdad as the center of Islamic civilization. In the Abbasid period, not only the Arabs filled the dynamics of Arab life, but also the Indians, Africans, Europeans, Persians, Chinese so as to form a cosmopolitical society, open, and easily accept new things that were considered useful.The dispute with the civilization of other nations brought a new influence so that science developed rapidly. In addition, the main influence is the leadership pattern of the caliphs who can provide progressive and revolutionary policies, namely providing support for the movement to translate foreign manuscripts, providing facilities for science lovers by establishing many libraries, especially Bayt al-Hikmah as an institution of education and science studies and as a library so that Muslim intellectuals are born.Key words: Abbasid Dynasty, Islamic Intellectuals
The Ottoman Turkish Expedition and the Anti-Colonialism Movement of the Sultanate of Aceh Darussalam 1530-1568
Authors: Haykal Muhammad
Published: December 2022

The appearance of the Portuguese fleet in the Indian Ocean and the Straits of Malacca was the starting factor for triggering colonialism in Nusantara. The emergence of the fleet which then continued to the domination of the Portuguese on the one hand had disrupted the expansion of the Ottoman Turks who had controlled Egypt and the Arabian Penisula. On the other hand, it was also the main factor that encouraged the emergence and development of the Aceh Darussalam Sultanate as a resistance movement or anti-colonialism against the Portuguese. This article will examine how the emergence of the Portuguese in the Indian waters and the Malacca Strait has become the main driver for the emergence of the anti-colonialism movement initiated by the Sultanate of Aceh. As well as the author continues by concluding that it was the the anti-colonialism movement became the main factor in establishing the relationship between the Aceh Darussalam Sultanate and the Ottoman Turks. However, this was because the Ottoman Turks also had the same interests as Aceh, namely against Portuguese domination in the Indian Ocean. To Ensure their trade flocks and Hajj route safe. The conclusion obtained is that the domination of the Portuguese in the Indian Ocean and the Straits of Malacca has indirectly become the main factor in the realization of military and even economic cooperation relations between the two Islamic empires. This paper is a research of literature and historiography using a narrative descriptive method, presenting history in combination with chronology and correlations between each event.Keywords: Aceh Darussalam, The Ottoman Turks, Anti-Colonialism Movement, Indian Ocean, Portuguese.
Wayang as a Media for Spreading Islam in the Archipelago
Authors: Sumawinata Shiska , Suryana Toto , Subakti Ganjar Eka
Published: December 2022

This article contains a discussion of the history of the spread of Islam through wayang art that developed in Nusantara. The writing of this article aims to explain the early arrival of Islam to Nusantara, the origin of wayang as a medium for the spread of Islam, to the role of wayang in the spread of Islam. In the preparation of this article, the author uses the literature study method to find and collect various relevant sources. Regarding wayang art, there are various Islamic religious values that can be found from wayang. The use of wayang as a medium for spreading Islam is thought to be inseparable from the initial position of wayang as an artistic performance used to spread religious, philosophical, and ethical teachings to humans. In addition, at that time wayang were also very popular with the public. The role of wayang in the spread of Islam is so important and this cannot be separated from the role of Wali Songo. Among them there are Sunan Giri, Sunan Kalijaga, and Sunan Bonang who preach using modified wayang as their medium. Both in terms of form and wayang stories have been adapted to Islamic teachings. When wayang has been adapted to Islamic teachings, people continue to like the art of wayang performed and can accept Islamic teachings easily. Keywords: Spread of Islam, Wali Songo, Wayang.
Development of the communicative competence of residents in the process of studying the course «pedagogy»
Authors:   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Ivashkina M.G. , Tarasova A.E. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation
Published: December 2022

The article deals with the development of the communicative competence of a resident in practical classes on the course «Pedagogy», shows the main communicative difficulties that are encountered in the work of a young doctor, suggests specific pedagogical techniques that help overcome communication difficulties.
Experience of teaching the discipline «outpatient therapy» in a remote format during the pandemic of covid-19
Authors:   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Larina V.N. , Golovko M.G. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Sayno O.V. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Soloviev S.S. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Orlov D.A. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation, Mironova T.N. ,   Federal State Autonomous Educational Institution of Higher Education «Russian National Research Medical University named after N.I. Pirogov of the Ministry of Health of the Russian Federation
Published: December 2022

The article presents the experience of teaching the discipline «outpatient therapy» in a remote format at the department of outpatient therapy of the medical faculty of the Russian National Research Medical University. N.I. Pirogov during the COVID-19 pandemic. The contribution of the department to the training of personnel for primary health care, the principles of organizing the pedagogical process in the epidemic period for interacting with students and monitoring the knowledge gained are presented. The importance of an automated educational system in the process of distance learning is discussed, which significantly accelerated and facilitated the work of the faculty of the department. The role of the «trigger mechanism» of distance learning for the intensification of the work of the department’s employees in the creation of educational, methodological, control and measuring materials and self-improvement for close interaction with technical innovations is noted. The remote type of work with students is possible, but it is not perfect - no «analogue» of the generally accepted training at the university can replace the «live communication» of the teacher with the student.
Implementasi Pelayanan Telefarmasi di Apotek Sesuai Standar Pelayanan Kefarmasian
Authors: Puspita Ivonn Elsa Aulia , Wibowo Ika Mulyono Putri , Kristianto Franciscus Cahyo
Published: December 2022

Penelitian ini ditujukan untuk menggambarkan implementasi pelayanan telefarmasi pada pelayanan farmasi klinis di apotek yang dipandang dari perspektif apoteker pemberi layanan. Penelitian ini merupakan penelitian deskriptif dengan metode survey menggunakan kuesioner. Kuesioner disusun berdasarkan standar pelayanan kefarmasian di apotek, dan pelayanan farmasi klinis yang terdiri dari 7 domain. Validasi kuesioner terlebih dahulu diuji validitas rupa (face validity). Sampel penelitian terdiri dari 40 apoteker yang berpraktik dan menyediakan pelayanan telefarmasi di apotek jaringan di Surabaya dan Sidoarjo. Sejumlah 34 apoteker yang memenuhi kriteria inklusi dan eksklusi terlibat dalam penelitian ini. Hasil penelitian menunjukkan bahwa pengkajian resep, dispensing dan KIE, pelayanan informasi obat, konseling, pemantauan terapi obat, home pharmacy care, dan monitoring efek samping obat selalu dan sering dilakukan oleh apoteker. Namun, dokumentasi konseling dan pemantauan terapi obat hanya dilakukan oleh 47,1% dan 55,9% responden. Berdasarkan hasil penelitian, dapat disimpulkan bahwa pelayanan telefarmasi pada pelayanan farmasi klinis sudah dilakukan dengan baik oleh apoteker.

 

Telepharmacy services have become part of pharmaceutical services in community pharmacy. Based on regulations, this service must be provided in accordance with pharmaceutical service standards in the community. This study aimed to describe the implementation of telepharmacy services in the community from the perspective of practicing pharmacists. This study is a descriptive research using survey method with a questionnaire. Questionnaires were prepared based on pharmaceutical service standards in pharmacies, and clinical pharmacy services consisting of 7 domains. The validity of the questionnaire was tested for face validity. The sample of this study was consisted of 40 pharmacists who practice and provide telepharmacy services at network pharmacies in Surabaya and Sidoarjo. A total of 34 pharmacists who met the inclusion and exclusion criteria were involved in this study. The results showed that the assessment of prescriptions, dispensing and communication-information-education, drug information services, counseling, monitoring of drug therapy, home pharmacy care, and monitoring of drug side effects were always and often carried out by pharmacists. However, documentation of counseling and monitoring of drug therapy was only carried out by 47.1% and 55.9% of respondents. Based on the results of this study, it can be concluded that telepharmacy in clinical pharmacy services have been carried out by pharmacist properly.