bluuebunny/crossref_metadata_2025 huggingface dataset:
Oleic Acid-PVA Based Amphiphilic Polymer Micelles for Vitamin D Encapsulation
Authors: BİRTANE Hatice
Published: November 2023

In this study, oleic acid-PVA based amphiphilic polymer micelles were prepared for vitamin D encapsulation. The amphiphilic polymer encapsulations were characterized using Fourier transformed infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy (1H-NMR). The goal of the study was to create micelles by using a lipophilic and biocompatible polymer. An oleic acid-substituted polyvinyl alcohol polymer was created through an acidic esterification reaction. The chemical structure of the polymer was disclosed by FTIR. To calculate the polymer's substitution ratio, 1H-NMR was used. Micellization was used to encapsulate vitamin D. Scanning electron microscope (SEM) analysis was used to determine the crucial micelle concentration and the size of the oleic acid-modified PVA. Ultraviolet–visible (UV) spectroscopy was used to analyze the release of vitamin D at various pH levels. As a result, vitamin D can be enclosed in PVA polymer that has been substituted with oleic acid.
Implementacija prenosnega EKG telesnega merilnika Savvy za presejanje motenj srčnega ritma na primarni zdravstveni ravni: intervencijska randomizirana kontrolirana študija
Authors: Vodička Staša
Published: November 2023

Na Inštitutu Jožefa Štefana so v sodelovanju z zdravniki razvili osebni prenosni merilnik EKG Savvy, ki deluje v kombinaciji s pametnim telefonom in ga lahko uporabljamo pri bolnikih, ki tožijo za motnjami srčnega ritma. Cilj študije je bil analizirati uporabnost telekardiologije na primarni zdravstveni ravni z uporabo prenosnega EKG telesnega merilnika Savvy.

Metode: Vključili smo 400 bolnikov s sumom na motnjo srčnega ritma, ki so od oktobra 2016 do januarja 2018 obiskali svojega družinskega zdravnika v Zdravstvenem domu Ljubljana in Zdravstvenem domu Murska Sobota. Bolniki so bili razdeljeni v testno skupino, kjer so dobili prenosni EKG telesni merilnik, in kontrolno, kjer ga niso.

Rezultati: Študija je pokazala, da med testno in kontrolno skupino ni statistično pomembne razlike glede odkritih motenj ritma in ukrepov za zdravljenje bolnikov, bodisi z opazovanjem bodisi z dajanjem novega zdravila. V testni skupini pa je bilo h kardiologu napotenih bistveno manj kot v kontrolni skupini (p <0,001).
Twenty New Additions to the Flora of Telangana State, India
Authors: Swamy J. , Rasingam L.
Published: November 2023

Twenty species are reported here as new additions to the flora of Telangana state from Amrabad Tiger Reserve, Kinnerasani and Manjeera Wildlife Sanctuaries. Out of twenty species, four species viz. Alysicarpus gautalensis Gholami & A.K.Pandey, Amorphophallus konkanensis Hett., S.R.Yadav & K.S.PatilÂ and Heterostemma disciflorum (Hook.f.) Swarupan. & Mangaly are endemic to Peninsular India. Brief descriptions, phenology and distribution and colour photos are provided for all species.
Lectotypification of two names in the genus Bupleurum L. (Apiaceae)
Authors: Rekha G. , Sujana K. A.
Published: November 2023

The lectotype for two names Bupleurum distichophyllum Wight & Arn. and Bupleurum ramosissimum Wight & Arn. are designated here.
An Annotated Checklist to the Alpine and Sub Alpine Flowering Plant Diversity of Dzongri-Goecha La Area, West Sikkim, India
Authors: Lahiri Subhajit , Dash Sudhansu Sekhar , Ghosh Asok
Published: November 2023

A total of 254 plant species belonging to 151 genera and 47 families were collected from alpine and subalpine regions of Dzongri Goecha La area. Of the total species collected, the first ten dominating family contributed more than 52.75% while the first ten dominating genera contributed 37.74 % of total genera of the studied area. 22 taxa have been reported new to region during the study.
A stage-based assessment of invasion and comparative inventory of the alien plants in Mizoram and Tripura, an Indo-Burma Biodiversity Hotspot region in India
Authors: Sengupta Rabishankar , Sekhar Dash Sudhansu
Published: November 2023

In the present paper an attempt has been made to evaluate the status of stage-based alien plant invasion in the natural forests of Mizoram and Tripura, a part of Indo-Burma hotspot regions of India. Occurrence of 163 alien plants in Mizoram and 186 alien plants in Tripura (Cumulatively 194 from both the states) were recorded during the study. Maximum species (52.15% in Mizoram and 57.52% in Tripura) were represented by top 10 families like Asteraceae, Leguminosae, Convolvulaceae, Euphorbiaceae etc. Among the alien plants of tropical American origin was maximum, followed by Mexican & Australian origin. The study also recommends the most obnoxious species, and neo-invasive plants, which are potential threats to the natural flora. The outcomes of the study can be used a baseline data of stage-based invasion of alien species in both the state and will be a useful resource for preparation of conservation or forest management policies.
REFLECTIONS FROM GOBEKLI TEPE IN CLOTHING DESIGN
Authors: ÇAŞKURLU Serap , KIR Betül , HACIOSMANOĞLU Can
Published: November 2023

Clothing fashion, which affects individuals and societies, is constantly changing with trends. The role of developed countries in fashion in the process leading to the deterioration of the natural balance is negatively reflected in the cultural creativity of developing and underdeveloped societies. The awareness of the cultural values of societies can be kept alive with the work of individuals in their fields. In our study, Göbekli Tepe, which is located in the Fertile Crescent region and revealed by excavations that it is the place where civilization was born and spread to the world, is discussed. Inspired by the finds, stelae, and symbols on the steles unearthed in the region, original clothes were designed with the patterns and forms obtained from the visuals of the finds by using Photoshop and CorelDraw computer programs. Our study will contribute to the preservation and maintenance of the importance and value of Göbekli Tepe today and in the future. Informing and raising awareness with similar studies will add value to the protection and preservation of our cultural values.
Understanding the behavioral intentions to consume ethnic food in the country of origin after experiencing local ethnic cuisines
Authors: Aziz Sadia , Zafar Shandana , Khan Niazi Muhammad Abdullah
Published: November 2023

Purpose – The purpose of the study is to investigate the role of cosmopolitan and ethnocentric behaviour of ethnic food consumer on the intention to consume ethnic food in country of origin (ICEC). Study aims to explain the consumption patterns of ethnic food consumers with the mediating role of utilitarian/hedonic values and perceived country image (PCI). In addition, the study explained consumption behavior with the moderating effect of food neophilia (FNP). Methodology/Design/Approach: Data were gathered from 969 respondents visited Chinese, Japanese, Italian, and Thai cuisines. Responses regarding experiences at ethnic cuisine were gathered through self-administrative survey. Findings: The results of the study showed a positive effect of consumer cosmopolitanism on ICEC and a negative effect of ethnocentric behavior on ICEC. Further study analyzed the mediating effect of hedonic and utilitarian values. The results showed that hedonic and utilitarian values significantly mediated the effect of cosmopolitanism/ethnocentrism on the ICEC. Moreover, PCI also showed significant serial mediation. The results indicate that high levels of FNP lead to high levels of ICEC. The originality of the research – The study presented a comprehensive model for analyzing the behavioral intentions of ethnic food consumers by combining social identity theory, hedonic value, and utilitarian value in culinary tourism.
Korean Audio-Visual Dataset of Characters in 3D Animation: Construction and Validation
Authors: Hyun Soobin , Son Yeongmin , Park Jae Wan
Published: November 2023

Characters are one of the most important elements in composing digital animation. The appear-ance and voice of a character should be designed to express the personality and values of the character. However, it is not easy for animation producers to harmoniously match the appear-ance and voice of a character. Advances in deep learning technology have made it possible to overcome this limitation. To achieve this, firstly, an audio-visual dataset of characters is required. In this study, we construct and verify a Korean audio-visual dataset consisting of frontal face im-ages of various characters and short voice clips. We developed an application that can automati-cally extract the frontal face image and a short voice clip of a character by collecting videos up-loaded to YouTube. Through this, a dataset consisting of a total of 1,522 face images and a total of 7,999 seconds of voice clips was built based on 490 characters. Furthermore, we automatically la-bel characters by gender and age to validate the dataset. The dataset built in this study is expected to be used in various deep learning fields, such as classification, generative adversarial networks, and speech synthesis.
Management of Juvenile Osteochondral Fractures Utilising Absorbable PLGA Implants
Authors: Nudelman Hermann , Lőrincz Aba , Lamberti Anna Gabriella , Varga Marcell , Kassai Tamás , Józsa Gergő
Published: November 2023

The incidence rate of articular injury is on the rise. With the help of imaging techniques, we classify the severity of the fracture and possible dislocations. Therapeutic interventions include the use of absorbable implants. The paper aims to present the surgical correction and post-operative treatment of osteochondral fractures with absorbable implants in three children. Affected areas are discussed as follows: lateral condyle of the femur, patella, and radial head. 1) A nine-year-old girl heard a sharp sound accompanied by pain after taking a careless step. Slight swelling of the knee was observed with the patella in place. Diagnostics revealed a broken piece of the femur’s lateral condyle located at the lateral recess. Under general anaesthesia, an arthrotomy was performed. The fragment was cleaned and reattached with absorbable nails. Postoperatively, a brace was applied for six weeks. 2) A 15-year-old boy was admitted due to a fall during ice skating, leading to rotational torsion of the knee. X-ray and CT imaging identified the osteochondral fracture of the patella. Based on these findings, an arthroscopy with arthrotomy was performed. 3) A 17-year-old girl fell while snowboarding, resulting in swelling of the proximal forearm. Imaging diagnostics confirmed the radial head fracture. Closed-fracture repositioning with absorbable implants was performed. The use of biodegradable implants eliminates the need for re-anaesthesia and reoperation, reducing the risks of complications. It also allows for earlier initiation of rehabilitation including physiotherapy. The efficiency of the method is further increased by a minimised hospital stay.
Ultrasonic and Microstructural Evaluation of Cemented Paste Backfill Properties Containing Alkali-Activated Slag: Effect of Slag Fineness
Authors: Cihangir Ferdi , Koc Ercument
Published: November 2023

Cement paste backfill (CPB) is an effective waste management method allowing the storage of fine process tailings into underground mined-out voids. CPB performance generally depends on the sulfur content of the tailings and the type of binder. In recent years, there has been an in-creasing trend on the use of alkali-activated slag (AAS) to improve the performance properties of CPB. This study focuses on the ultrasonic and microstructural investigation of the effect of slag fineness on the mechanical, geochemical and durability properties of CPB made up of AAS (AAS-CPB) over 360 days. In this scope, AAS-CPB samples were prepared at three different fineness (3100-4650-6300 cm2/g). Fineness of slag significantly improved the early age- and long-term strength (~2.3 fold and ~6.6 fold, respectively) of CPB. However, further increase of slag fineness may have adverse effect on CPB microstructure and strength in the long term. Ultrasonic pulse velocity monitoring displayed very high relation with the strength evolution and durability assessment of CPB. Slag fineness at a degree was seen to improve the pore structure evolution of AAS-CPB. Microstructural studies are in good agreement with the geochemical and durability behavior of AAS-CPB. Microstructural and ultrasonic findings suggest that while slag fineness enhances the mechanical properties of AAS-CPB, further increase of the fineness of slag has no additional important technical advantages.
Guanylyl Cyclase Activator Improves Endothelial Function by Decreasing the Concentration of Superoxide Anions
Authors: Martinelli Ariane M , De Moraes Luis Henrique Oliveira , De Moraes Thiago Francisco , Rodrigues Gerson Jhonatan
Published: November 2023

Introduction: activation of soluble guanylyl cyclase (sGC) in smooth muscle vascular is able to induces vasodilation. The chronic activation of sGC was able to improves vascular function in congestive heart failure animal model. Thus, activation of sGC can be a way to vasodilation and improvement in endothelial function. Objective: Investigate whether the selective activator of sGC can revert the endothelial dysfunction, and investigate the mechanism of action. Methods: Normotensive (2K) and hypertensive (2K-1C) wistar rats were used. Intact aortic rings were placed in a myograph and incubated with atacicguat 0.1 µM during 30 min. Cumulative concentration-effect curves to acetylcholine (Ach) were performed to measure the endothelial function. The pD2 and maximum relaxant effect (Emax) was measured to Ach. In endothelial cell culture, the detection of superoxide anion (O2•-) was made by using fluorescent probes, including DHE and lucigenin. Results: Ataciguat improved the relaxation induced by acetylcholine in 2K-1C(pD2: 6.99 ±0.08, n=6) compared to control(pD2: 6.43±0.07, n=6, p<0.05), also improved in aortic rings from 2K(pD2: 7.04±0.13, n=6), compared to control(pD2: 6.59±0.07, n=6, p<0.05). Also, Emax was improved by ataciguat treatment in the 2K-1C aorta (Emax: 81.0±1.0; n=6), and 2K aorta (Emax: 92.98±1.83; n=6), compared to control (Emax 2K-1C: 52.14 ±2.16, n=6; and Emax 2K: 76.07±4.35, n=6, p<0.05). In endothelial cell culture, treatment with ataciguat (0.1, 1 and 10 µM) decreased the superoxide anion formation induced by angiotensin II. Conclusions: our results suggest that ataciguat were able to improve endothelial function by superoxide anion inactivation.
Uptake and Completion of Tuberculosis Preventive Treatment Using 12-Dose, Weekly IsoniazidRifapentine Regimen in Bangladesh: A CommunityBased Implementation Study
Authors: Rahman Md. Toufiq , Hossain Farzana , Banu Rupali Sisir , Islam Md. Shamiul , Alam Shamsher , Faisel Abu Jamil , Salim Hamid , Cordon Oscar , Suarez Pedro , Hussain Hamidah , Roy Tapash
Published: November 2023

Background: The UNHLM pledged to enroll 30 million in TB preventive treatment (TPT) by 2022, necessitating TPT expansion to all at TB risk. We assessed uptake and completion of a 12-dose, weekly isoniazid-rifapentine (3HP) TPT regimen.

Methods: Between February 2018 - March 2019 in Dhaka, community-based TPT using 3HP targeted household contacts of 883 confirmed drug-sensitive pulmonary TB patients. Adhering to WHO guidelines, contacts underwent active TB screening before TPT initiation.

Results: Of 3,193 contacts who advised health facility visits for screening, 67% (n=2,149) complied. Among these, 1,804 (84%) received chest X-rays. Active TB was diagnosed in 39 (2%) contacts; they commenced TB treatment. Over 97% of 1,216 contacts began 3HP TPT, with completion rates higher among females, those with more education and income, non-slum residents, and those without 3HP-related adverse events. Adverse events, mainly mild, occurred in 5% of participants.

Conclusions: The 3HP weekly regimen, with its short duration, self-administered option, and minimal side effects, achieved satisfactory completion rates. A community-focused 3HP TPT approach is feasible, scalable nationally, and aligns with UNHLM targets.
Advances in Tilapia farming: Statistical Analysis of the Use of Probiotics and Assessment of their Potentials and Challenges
Authors: Pereira Wellison Amorim , Reis Iara , Villasante Alejandro , Ramírez Carolina , Franco Sara , Mendonça Carlos M.N. , Dias Danielle de Carla , Tachibana Leonardo , Converti Attilio , El-Sayed Abdel-Fattah M. , Romero Jaime , Figueroa Villalobos Elias , Oliveira Ricardo Pinheiro de Souza
Published: November 2023

Data regarding the pandemic's impact on tilapia culture remain limited, but it is known that there was a significant decline in production and marketing since 2020. The post-pandemic challenges confronting tilapia farming necessitate prompt solutions, encompassing the management of bacterial infections and the adoption of more advanced technologies by small-scale producers in developing nations. Probiotics, acknowledged as a viable alternative, are presently extensively employed in tilapia aquaculture. Multiple studies have suggested that the application of diverse probiotics in tilapia culture has yielded favorable outcomes. Nonetheless, only a limited number of studies have employed statistical methods to evaluate such findings. To address this gap, a regression analysis was carried out to investigate the existence of a linear relationship between the probiotic dosage added to the feed and two key dependent variables: the specific growth rate (SGR) and the feed conversion ratio (FCR). Additionally, a hierarchical regression analysis was undertaken to ascertain the extent to which the variance observed in these responses could be explained by the variable "probiotic dosage in feed," after accounting for covariates such as initial weight, test duration, water temperature, and number of replicate tanks. Finally, two Pearson correlation matrices were constructed since different studies were included for the SGR and FCR analyses.
A Potential Approach for Paracetamol Removal from Aqueous Environments: Graphene Oxide-Polymer Nanocomposite Beads
Authors: Alhoshan Mansour , Shukla Arun Kumar , Alam Javed , Hamid Ali Awadh
Published: November 2023

This study introduces a promising and practical method for the removal of paracetamol from aqueous environments, employing graphene oxide-polymer nanocomposite beads. The approach involves the utilization of a straightforward and facile phase inversion method, offering a convenient and efficient one-step process for the creation of adsorbent beads by integrating polymers and graphene oxide (GO). The synthesized nanocomposite beads are tailored for the removal of paracetamol from simulated wastewater in batch systems. Extensive characterization techniques are employed to scrutinize the chemical properties and structural attributes of the prepared beads. The investigation explores the impact of critical parameters such as adsorbent dosage, adsorption duration, initial paracetamol concentration, and solution pH on the adsorption process. These nanocomposite beads exhibit an exceptional paracetamol removal efficiency, achieving up to 99% removal. This research not only contributes to the advancement of efficient and sustainable adsorbent materials for pollutant removal but also underscores their potential for environmentally friendly and cost-effective solutions in the domain of wastewater treatment.
Association of Periodontal Disease with Activity of Crohn's Disease
Authors: Živić Miloš , Zdravkovic Nebojsa , Stojanovic Bojan , Milosevic Bojan , Todorovic Zeljko , Adamović Miljan , Zdravkovic Natasa
Published: November 2023

Introduction: Crohn's disease (CD) is a chronic inflammatory granulomatous disease that can affect the entire gastrointestinal tract. It is characterized by various extraintestinal manifestations (EIM), of which oral manifestations (OM) are often possible. One of the possible OM is periodontal disease (PD) a chronic inflammatory condition of the supporting tissues of the teeth. This study aimed to show the existence of a mutual relationship between the clinical activity of PD and the clinical and endoscopic activity of CD.
Materials and methods: Using one clinical and two endoscopic indexes for the assessment of CD activity and clinical attachment loss (CAL), bleeding on probing (BOP), pocket probing depth (PPD) and radiographic bone loss (RDL) on dental panoramic tomogram to assess PD in CD patients.
Results: A total of 38 patients underwent the entire study process, of which 20 patients with CD and 18 patients with CD and PD. Considering all CD activity scores, there were 26 patients with active disease, and half of them had PD, and 85.7% of operated patients had active CD. Values of CAL, PPD, BOP and RBL were higher in active CD than remission, except BOP when compared to CDAI score which was higher in remission of CD.
Discussion and conclusion: The results of this study indicate that there is a connection between the activity of CD and the worse condition of the supporting tissues of the gums in the oral cavity which is important to keep in mind the necessity of referring patients with CD to a dentist for timely and adequate therapeutic measures.
Advances in Research on Marine-Derived Lipid-Lowering Active Substances and Their Molecular Mechanisms
Authors: Liu Lina , Chen Yihui , Chen Bei , Xu Min , Liu Shuji , Su Yongchang , Qiao Kun , Liu Zhiyu
Published: November 2023

Hyperlipidemia (HLP) is a metabolic disease caused by abnormal lipid metabolism. Recently, the prevalence of HLP caused by poor dietary habits in the population has been increasing yearly. In addition, the current clinical use of lipid-lowering drugs has significant ameliorating effects on lipid levels but these actions are accompanied by certain side effects. However, bioactive marine substances have been verified to have various physiological activities such as hypoglycemic, antioxidant, antithrombotic, and effects on blood pressure. Therefore, marine biological sources of hypolipidemic active substances have attracted much attention. Moreover, some of the identified active substances have been found to induce hypolipidemia by inhibiting cholesterol synthesis and absorption, or by improving the composition of intestinal microorganisms. This article introduces the sources and classification of marine-derived hypolipidemic active substances, and describes current progress in research on the main mechanism of the hypolipidemic activity of these substances.
High-Temperature Lightweight Ceramics with Nano-sized Ferrites for EMI Shielding: Synthesis, Characterization, and Potential Applications
Authors: Abramovskis Vitalijs , Zalite Ilmars , Maiorov Mikhail , Baronins Janis , Singh Ashish Kumar , Lapkovskis Vjaceslavs , Goel Saurav , Shishkin Andrei
Published: November 2023

Present study focuses on the synthesis and characterisation of a lightweight ceramic material with electromagnetic interference (EMI) shielding properties, achieved using mullite containing micrometer-sized hollow spheres (cenospheres) and CoFe2O4 nanoparticles. The research explores compositions with varying CoFe2O4 content, ranging from 0 up to 20 wt.%. Сonventional sintering in an air atmosphere is carried out at a temperature between 1100-1300 °C. The addition of ferrite nanoparticles was found to enhance the sintering process of cenospheres, resulting in improved material density and mechanical properties. Furthermore, the study reveals a direct correlation between the concentration of ferrite nanoparticles and the electromagnetic properties of the. By increasing the concentration of ferrite nanoparticles, the electromagnetic shielding effect of the material (saturation magnetization (Ms) and remanent magnetization (Mr)) was observed to strengthen. These findings provide valuable insights into the design and development of lightweight ceramic materials with enhanced electromagnetic shielding capabilities. The synthesized ceramic material holds promise for various applications that require effective electromagnetic shielding, such as in electronics, telecommunications, and aerospace industries.
Converting Human Power into Electricity: Current Status and Future Directions
Authors: Ding Qirui , Yang Jinjing , Cui Weicheng
Published: November 2023

This comprehensive review explores the principles, applications, and future directions of human-powered energy generation technologies. It begins by providing a detailed examination of viable human energy sources, elucidating the physical principles behind various energy harvesting devices. The review then compiles and assesses existing products in the field of human power generation, while also outlining the opportunities and challenges it presents. Finally, an innovative concept of an eco-village system is introduced to demonstrate a future potential application scenario for human-generated electricity. It outlines two developmental stages for this system and underscores its significance in the construction of the harmonious and sustainable communities. This forward-thinking approach could pave the way for broader discussions on sustainable living and eco-friendly energy generation in a world increasingly focused on environmental concerns and social stability.
BNT162b2 Booster Dose Elicits a Robust Antibody Response in Subjects with Abdominal Obesity and Previous SARS-CoV-2 Infection
Authors: Malavazos Alexis Elias , Dubini Carola , Milani Valentina , Boveri Sara , Meregalli Chiara , Bertolini Caterina , Buscemi Carola , Cardani Rosanna , Renna Laura Valentina , Trevisan Manuel Bruno , Scravaglieri Valentina , Cuppone Maria Teresa , Menicanti Lorenzo , Costa Elena , Ambrogi Federico , Ruocco Chiara , Carruba Michele , Iacobellis Gianluca , Nisoli Enzo , Corsi Romanelli Massimiliano Marco
Published: November 2023

Little is known about the long-term durability of the induced immune response in subjects af-fected by obesity, particularly in those with an abdominal distribution of adipose tissue. We evaluated SARS-CoV-2-specific antibody response after BNT162b2 vaccine booster dose, com-paring individuals with abdominal obesity (AO) with those without, discerning between indi-viduals previously infected or not. IgG-TrimericS were measured in 511 subjects at baseline, 21 days after vaccine dose-1 and at one, three, six and nine months after dose-2 and at one and three months after booster dose. Nucleocapsid antibodies were assessed at baseline and at the end of the study to detect SARS-CoV-2 infection. To evaluate the three-months difference in absolute variation of IgG-TrmicericS levels from booster dose we used multivariable linear regression that showed interaction between AO and SARS-CoV-2 infection status (p=0.016). AO is associated with higher absolute IgG-TrimericS variation in prior infected individuals, regardless of possi-ble confounders and IgG-TrimericS levels at booster dose (p=0.0125). No interaction was evinced using BMI in the same regression model (p=0.418). The robust response in the development of antibodies after booster dose, observed in people with OA and previous infection, may support the recommendations to undergo the booster dose also in this population group.
Synthesis and Crystallization of N-rich Triazole Compounds
Authors: Parisi Emmanuele , Centore Roberto
Published: November 2023

This work aimed to synthesize new N-rich triazole compounds. In this article we describe the synthesis of three different 1,2,4-triazole-based systems starting from 1,3-diaminoguanidine hydrochloride monohydrate. The structure of the obtained crystals was established by single-crystal X-Ray diffraction. The high nitrogen content of the synthetized compounds makes them building blocks for the application in the High-Energy-Density material science.
Dynamics Management of Intermediate Water Storage in an Air-Breathing Single Cell Membrane Electrode Assembly
Authors: Kumar Avinash , Schechter Alex , Avrahami Idit
Published: November 2023

In air-breathing proton exchange membrane fuel cells (Air PEM FCs), high rate of water evaporation from the cathode might influence the resistance of the membrane electrode assembly (MEA), which is highly dependent on the water content of the Nafion membrane. We propose a dead-end hydrogen anode as a means of intermediate storage of water/humidity for self-humidification of the membrane. Such inflatable bag integrated with the PEM FC has a potential in blimp applications for anode self-humidification. A dynamic numerical water balance model, validated by experimental measurements, is derived to predict the effect of MEA configuration, membrane’s hydration state, and water transfer rate at the anode on MEA resistance and performance. The experimental setup included humidity measurements, polarization and electrochemical impedance spectroscopy tests to quantify the effect of membrane hydration on its resistance in a lightweight MEA integrated with an inflatable dead-end hydrogen storage bag. Varying current density (20 mA, 40 mA and 60 mA) and cathode humidity (20, 50 and 80%) were examined and compared with the numerical results. The validated model predicts that the hydration state of the membrane and water transfer rate at the anode can be increased by using a thin membrane and thicker gas diffusion layer.
Molecular Identification of Fungal Species by Multiplex-qPCR in Candidal Vulvovaginitis Specimens and Antifungal Susceptibility
Authors: Arrieta-Aguirre Inés , Menéndez-Manjón Pilar , Carrano Giulia , Diez Ander , Fernandez de Larrinoa Íñigo , Moragues María-Dolores
Published: November 2023

Vulvovaginal candidiasis (VVC) is a prevalent condition affecting women worldwide. This study aimed to develop a rapid qPCR assay for accurate identification of VVC etiological agents and reduced azole susceptibility. One hundred and twenty nine vaginal samples from an outpatient clinic (Bilbao-Spain) were analyzed using culture-based methods and multiplex qPCR targeting fungal species, Candida albicans being the predominant species. Antifungal susceptibility tests revealed reduced azole susceptibility in three (3,48%) isolates. Molecular analysis identified several mutations in genes associated with azole resistance and novel mutations in TAC1 and MRR1 genes were also identified, which could contribute to drug resistance.
A Systematic Review of Recent Deep Learning Approaches for 3D Human Pose
Estimation
Authors: EL KAID Amal , BAÏNA Karim
Published: November 2023

3D human pose estimation has made significant advancements through the integration of deep learning techniques. This survey provides a comprehensive review of recent 3D human pose estimation methods, with a focus on monocular images, videos, and multi-view cameras.
Our approach stands out through a systematic literature review methodology, ensuring an up-to-date and meticulous overview. Unlike many existing surveys that categorize approaches based on learning paradigms, our survey offers a fresh perspective, delving deeper into the subject.
For image-based approaches, we not only follow existing categorizations but also introduce and compare significant 2D models. Additionally, we provide a comparative analysis of these methods, enhancing the understanding of image-based pose estimation techniques. In the realm of video-based approaches, we categorize them based on the types of models used to capture inter-frame information.
Furthermore, in the context of multi-person pose estimation, our survey uniquely differentiates between approaches focusing on relative poses and those addressing absolute poses.
Our survey aims to serve as a pivotal resource for researchers, highlighting state-of-the-art deep learning strategies and identifying promising directions for future exploration in 3D human pose estimation.
Tamm Plasmon Polariton Biosensors based on Porous Silicon: Design, Validation and Analysis
Authors: Rong Guoguang , Sawan Mohamad
Published: November 2023

Tamm Plasmon Polariton (TPP) is a nanophotonic phenomenon that has attracted much attention due to its spatial strong field confinement, ease of mode excitation and polarization independence. TPP has applications in sensing, storage, lasing, perfect absorber, solar cell, nonlinear optics, and many others. In this work, we demonstrate a biosensing platform based on TPP resonant mode. Both theoretical analyses based on Transfer Matrix Method and experimental validation through nonspecific detection of liquids of different refractive indices and specific detection of SARS-CoV-2 nucleocapsid protein (N-protein) are presented. Results show that TPP biosensor has high sensitivity and good specificity. For N-protein detection, the sensitivity is 1.5 nm/(µg/ml) and the limit of detection can reach down to below 7 ng/ml with spectrometer of 0.01 nm resolution of wavelength shift. This work paves the way for design, optimization, fabrication, characterization, and performance analysis of TPP based biosensors
Periodic Behavior of Selected Solar, Geomagnetic and Cosmic Activity Indices during Solar Cycle 24
Authors: Kilcik Ali , Ozguc Atila , Rozelot Jean-Pierre
Published: November 2023

In this study, we performed periodicity analyzes of selected daily solar (FI, CI), geomagnetic (Ap, Dst, Scalar B) and cosmic (CRI) activity indices for the last solar Cycle 24 (December 2008 to December 2019). To investigate the periodic variations of above selected data sets the Multi Taper Method (MTM), Morlet wavelet, Cross Wavelet Transform (XWT), and Wavelet Coherence (WTC) analysis techniques were used. In results of our analysis we found that i) the 25-33 and 2048-day periodicities exist in all data sets without any exception, while all other detected periodicities have data preferences, ii) all detected periods located around the maximum phase of the cycle (Cycle 24), iii) the phase relations between compared data sets periodicities are gradually changing from small periods to large ones; there are no phase relations between small periodicities and they show mixed phases, while they are completely in phase/antiphase for large periodicities, iv) all detected FI periodicities, except 2048 days periodicity, are common periodicities with all other data sets used in this study.
Inflammation Indexes PLR, SII, AISI, MLR, and MCVL in Peripartum Treated Thrombophilia Peripartum Patients Undergoing Cesarean Section at Term
Authors: Filip Catalina , Covali Roxana , Socolov Demetra , Vasilache Ingrid Andrada , Carauleanu Alexandru , Akad Mona , Scripcariu Ioana Sadyie , Butureanu Tudor , Pavaleanu Ioana , Dumachita-Sargu Gabriela , Boiculese Lucian Vasile , Melinte Alina , Socolov Razvan
Published: November 2023

(1) Background: Thrombophilia is a tendency towards hypercoagulability, and it is increased by pregnancy, and peaking around delivery.; (2) Methods: 80 Eighty thrombophilia patients admitted for delivery between 1/10/2017 and 1/12/2021 were prospectively studied, together with 80 eighty age- and para-matched control patients. Patients were admitted for delivery at term by means of cesarean section. The inflammation indexes from the complete blood count values analysis, in during both the 24 hours before and the 24 hours after labor—, extracted from the hospital’s medical records—, were calculated, and then correlated with uterine involution.; (3) Results: In pregnant patients treated for thrombophilia patients, the patients who did not manage to have close their uterine cavity closed with in the first 24-48 hours had significantly higher SII and AISI inflammation indexes SII and AISI , than the onesthose who did manage to have their uterine cavity closed their uterine cavity. In pregnant patients treated for thrombophilia patients, MLR is higher in patients without the Rh factor than in those with the Rh factor. In non-thrombophilia patients, PLR was significantly higher as compared to treated thrombophilia patients. In non-thrombophilia patients, MCVL increased with age and, before labor, while SII and AISI increased with age, postpartum. ; (4) Conclusions: There may be an underlying inflammation state that persisted despite treatment in some pregnant thrombophilia pregnant patients.
The Influence of Mobility Training on the Myofascial Structures of the Back and Extremities
Authors: Slomka Gunda , Schleip Robert , Frei Peter , Krämer Michael , Kurpiers Nicolas , Bauermeister Katharina , Bauermeister Wolfgang
Published: November 2023

The research methods were used to investigate the following questions: Does a mobility training intervention change tissue stiffness, joint range of motion, and compensate for possible imbalances? Do the interventions influence the pressure pain threshold and the overall well-being?
Growth, Structure, Spectroscopy and Laser Operation of a “mixed” Yb:(Y, Lu)3Al5O12 Garnet Crystal
Authors: Slimi Sami , Loiko Pavel , Pan Mingyan , Lehoux Pauline , Jambunathan Venkatesan , Srmž Martin , Mocek Tomáš , Wang Yicheng , Petrov Valentin , Chen Weidong , Solé Rosa Maria , Aguiló Magdalena , Díaz Francesc , Camy Patrice , Mateos Xavier
Published: November 2023

A single-crystal of ytterbium-doped “mixed” yttrium-lutetium aluminium garnet with a stoichiometric composition of (Y0.601Lu0.233Yb0.166)3Al5O12 was grown by the Czochralski method and its structure, vibronic, spectroscopic and laser properties were studied. The stimulated-emission cross-section for Yb3+ ions was maximized to 2.53×10-20 cm2 at 1031 nm, the emission bandwidth is ~8 nm and the reabsorption-free luminescence lifetime of the 2F5/2 state is 1.063 ms. Pumped at 941 nm, the Yb-laser generated a maximum output power of 1.04 W at 1.03 and 1.05 μm with a high slope efficiency of 76.4% and a laser threshold of 76 mW. A continuous wavelength tuning over a range of 51.6 nm (1026.4 - 1078.0 nm) was also achieved. Power scaling is achieved using a 969 nm-diode pumped microchip cavity. A maximum output power of ~9 W is obtained at 1.05 μm with a slope efficiency of 76% and with an almost circular laser beam profile.
Physicochemical Characteristics and Antimicrobial Efficacy of Plasma-Activated Water Produced by an Air-Operated Coaxial DBD Plasma
Authors: Miranda F. S. , Tavares V. K. F. , Gomes Marcelo Pego , Neto Nilton , Chiappim W. , Petraconi Gilberto , Pessoa Rodrigo , Koga-Ito Cristiane
Published: November 2023

In this study, Plasma-Activated Water (PAW) was synthesized using a coaxial Dielectric Barrier Discharge (DBD) reactor, benefiting from the elevated capacity of air-flow-assisted DBD discharges to enhance nitrogen-based species concentration. By manipulating operational parameters, including gas flow rate, activation time, and DI water volume, we achieved significant concentrations of Reactive Oxygen and Nitrogen Species (RONS). As a result, the PAW obtained displayed pronounced physicochemical attributes: a pH of 2.06, an ORP of 275mV, conductivity of 3mS/cm, and TDS of 1200 mg/L. A pivotal aspect of this research was the evaluation of the reactor's efficiency, as indicated by metrics like the specific input energy and ozone efficiency yield. The antimicrobial potential of the PAW was also assessed against pathogenic microbes, with remarkable reductions in viability for both Staphylococcus aureus and Escherichia coli (99.99%) and a more moderate decrease for Candida albicans (37%). These findings underscore the capability of the coaxial DBD reactor in crafting high-quality PAW with significant antimicrobial properties, necessitating further studies to validate its broad-spectrum and safe application.
The Avian Acetabulum: Small Structure, but Rich with Illumination and Questions
Authors: Feduccia Alan
Published: November 2023

That birds are maniraptoran theropod dinosaurs is now considered an evolutionary consensus. An “open” (i.e., completely, or substantially perforate) acetabulum is considered an important synapomorphy verifying the bird-dinosaur nexus. Here I present anatomical evidence from morphological aspects of the acetabulum and its important appurtenances, the supracetabular crest and the antitrochanter, that the hip anatomy differs substantially between dinosaurs and birds and for the current hypothesis of origins to be correct unlikely anatomical reversals would have been required. Given the thin bone of the acetabular walls and the varied tissue, both hard and soft, in the acetabular region and especially the lower part of the basin, it is apparent that many avian skeletons exhibit some anatomical loss of soft tissue and thin bone, some perhaps related to changes in gait, but also in part related to the dramatic trend in bone reduction associated with flight, especially in more advanced crown taxa. Many basal birds and early diverging neornithines tend to have a nearly closed or various levels of partially closed acetabula, thus rendering the current terms “open” or “closed” acetabula inaccurate; they should be modified or replaced.
A New Mixed Fractional Derivative with Application to Computational Biology
Authors: Hattaf Khalid
Published: November 2023

This study develops a new definition of fractional derivative that mixes the definitions of fractional derivatives with singular and non-singular kernels. Such developed definition encompasses many types of fractional derivatives, such as the Riemann-Liouville and Caputo fractional derivatives for singular kernel type as well as the Caputo-Fabrizio, the Atangana-Baleanu and the generalized Hattaf fractional derivatives for non-singular kernel type. The associate fractional integral of the new mixed fractional derivative is rigorously introduced. Furthermore, newly numerical scheme is developed to approximate the solutions of a class of fractional differential equations (FDEs) involving the mixed fractional derivative. Finally, an application to computational biology is presented.
Graph Propagation Dynamics of an Epidemic Model with Heterogeneous Control Strategies on Complex Networks
Authors: Wang Yan , Chen Shanshan , Yu Dingguo , Liu Lixiang , Shang Ke-ke
Published: November 2023

The stability and optimal control for an SIS epidemic model with demographics and heterogeneous control strategies (immunization and quarantine) on complex networks are investigated. The epidemic threshold, disease-free and endemic equilibria are derived. Then, global asymptotical stability about the two equilibria are studied based on different methods. Furthermore, the optimal control issue about the system is also considered. We obtain the existence and uniqueness of the optimal control and optimal control tactics. Some numerical simulations were conducted to illustrate and supplement the theoretical results. Meanwhile, the effects of the combination of various immunization and quarantine schemes are studied and also compared with the optimal control strategies.
Beyond Deep Learning—Space, Time, and Emergence
Authors: Wang Ge , Fan Feng-Lei
Published: November 2023

In this perspective article, we ponder topographical enhancements of artificial neural networks. In our recent paper in JMLR, we proved a quasi-equivalence between the network width and depth and also discussed the power of intra-links, which can be viewed as network height. In 1982, Hopfield published a network to model human associative memory, which contains many loops for dynamic evolution toward fixed points. Based on noising-denoising loops, diffusion models are recently developed to enable Bayesian modeling and inference with big data. Furthermore, we envision development of multi-AI-agent systems through “netware” engineering as a quantum leap of software engineering for emergent behaviors and autonomous AI at individual and population levels. We believe that the novel use of links and loops in space and time via multi-scale coupling would catalyze the next-generation neural networks.
The Individual Work Performance Questionnaire: Psychometric properties of the Italian version
Authors: Platania Silvia , Morando Martina , Gruttadauria Stefania Valeria , Koopmans Linda
Published: November 2023

The Individual Work Performance Questionnaire (IWPQ) can be defined as the individual be-haviour capable of generating value and competitive advantage for the organization. It is a mul-ti-dimensional construct, consisting of task performance, contextual performance and counter-productive work behavior. Albeit important, a comprehensive measure of individual job per-formance is still lacking in the Italian context. This paper describes the validation of an Italian adaptation of the IWPQ. A back translation procedure was used. To investigate the psychometric properties of the 18-item Italian IWPQ, 1053 participants (502 men, 47.7%; 551 women, 52.3%) were enrolled; the age of participants ranged between 19 and 69 (Mage=34.6, SD= 11.8), and for the oc-cupation, the sample is classified in blue collar 32.5%, pink collar 33% and white collar 34.5%. Exploratory and confirmatory factor analyses and multigroup confirmatory factor analyses were performed to test the structural factor of the IWPQ. The results supported the goodness of the IWPQ in the Italian context and the scales were found consistent with the original structure. One item was omitted due to a low factor loading, resulting in a final 17-item structure. Multigroup confirmatory factor analysis showed that the factor solution was invariant across both gender and occupational category and found evidence of metric invariance, uniqueness and scalar invariance, and structural invariance. Convergent and discriminant validity were also tested and showed.
Direct Oral Anticoagulants Consumption and Expenditure in Covid-19 Pandemic in Russia and Clinical Practice Guidelines for Their Use
Authors: Baybulatova Elena A. , Ziganshina Liliya Eugenevna , Zyryanov Sergey K. , Korovyakova Elina A. , Chenkurov Mikhail S.
Published: November 2023

Background
The coronavirus pandemic has led to the creation of clinical guidelines by a large number of professional medical communities. However, the quality and methodology of development of Russian clinical guidelines has been little studied. The continued relevance of studying the use of DOACs in patients with COVID-19 was the basis for conducting this study.
Aim
The objective of this study was to assess DOACs consumption and expenditures in Russian Federation during COVID-19 pandemic and to analyse domestic evidence base for the use of DOACs in COVID-19 patients through identifying all publicly available Russian-produced CPGs for the treatment of COVID-19 and assessing their quality as the source of recommendations for the use of oral anticoagulants for the prevention of thrombotic complications in COVID-19 patients.
Methods
We searched Russian databases for CPGs, published between 2020 and 2023. We identified 7 relevant documents that met our inclusion criteria.
Three authors analyzed Russian clinical guidelines using a AGREE II questionnaire.
We calculated DOACs DDD consumption according to Russian clinical guidelines and DDD consumption in patients with COVID-19 for the period 2020-2022.
Results
7 clinical CPGs were analyzed with the AGREE II tool, it was revealed that experts gave the highest scores for the sections scope and purpose (from 62.98% to 100%), clarity of presentation (from 96.30% to 100%). The lowest scores were given for the sections stakenholder involment (33.33% to 64.81%), rigour of development (from 0% to 49.31%), applicability (from 23.61% to 50%), editory independence ( from 0% to 50%). When comparing the total score, it was found that two clinical guidelines received the highest scores - ROPNIZ (Livzan), ROPNIZ (Drapkina). The minimum score is registered with the NIIOZMM (Khripun) clinical guideline. No guideline received a total score of more than 70%.
According to clinical recommendations, the consumption of apixaban and rivaroxaban is 15 DDD (30-day course of therapy), 22.5 DDD (45-day course of therapy).
Consumption of apixaban in the Russian Federation in 2020 and 2021 corresponds to the indicators presented in clinical recommendations (in 2020 – 26.59 DDD per patient with COVID-19; in 2021 – 15.75 DDD per patient with COVID-19), and in 2022 – 10.67 DDD, which is below the recommended values. In 2020, consumption of rivaroxaban in the Russian Federation was 26.59 which corresponds to data from clinical recommendations; in 2021, consumption decreased to 7.87 DDD; in 2022 – 5.48 DDD, which is 2.74 times less than recommended.