bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS KUALITAS LAYANAN DISTRIBUSI DENGAN METODE PHYSICAL DISTRIBUTION SERVICE QUALITY (PDSQ) DI PT. X
Authors: Ocsylia Francisca , Pulansari Farida , Samanhudi Didi
Published: July 2019

Di era persaingan bisnis yang sangat kompetitif saat ini, perusahaan harus mampu menyusun strategi yang tepat agar dapat mempertahankan kepuasaan dan loyalitas pelanggan. Loyalitas pelanggan akan dapat dipertahankan dan terwujud apabila perusahaan memberikan kualitas layanan yang sesuai dengan persepsi dan harapan pelanggan. Loyalitas pelanggan juga mengekspresikan perilaku yang berkaitan dengan produk maupun jasa.

PT X merupakan perusahaan distributor alat kesehatan di daerah Jawa Timur. Alat kesehatan yang dijual di perusahaan ini antara lain kursi roda, perban, kantong darah, masker, dan lain-lain. Kegiatan yang dilakukan PT. X mengambil produk-produk alat kesehatan dari beberapa perusahaan, menyimpan, serta mengantarkannya kepada konsumen. PT. X memiliki armada pengangkutan sendiri untuk mengantar pesanan ke tempat konsumen. Adapun tujuan penelitian ini adalah mengetahui kualitas pelayanan distribusi di PT. X dan memberikan usulan perbaikan terhadap pelayanan.

Dari hasil analisa penelitian  dan pembahasan yang telah dilakukan, maka dapat ditarik kesimpulan bahwa kualitas pelayanan di PT. X belum memuaskan karena 27,27% indikator empiris kualitas layanan distribusi bernilai negatif atau belum sesuai dengan ekspektasi konsumen. Usulan perbaikan  kualitas layanan distribusi di PT. X, yaitu: menambah armada baru atau memaksimalkan muatan barang dalam satu amarda, menetapkan prioritas utama pengiriman produk ke pelanggan yang terdekat terlebih dahulu. Disamping itu perusahaan juga perlu membuat batas minimum stok dengan memperhitungkat lead time dan melakukan evaluasi dalam pengendalian persediaaan. Penambahan jumlah Customer Service dan melakukan pencatatan rutin setiap ada komplain dari konsumen serta melakukan evaluasi untuk melakukan perbaikan.
ANALISA KUALITAS JASA PENERBANGAN LION AIR DENGAN METODE QUALITY FUNCTION DEPLOYMENT (QFD)
Authors: Aryanny Enny , Iriani Iriani
Published: July 2019

Lion Air sebagai salah satu perusahaan penerbangan di Indonesia dihadapkan dengan persaingan pasar yang kompetetif dan dinamis baik dengan pemain lama maupun perusahaan baru. Kondisi tersebut mengharuskan Lion Air untuk mampu terus meningkatkan kualitas jasa penerbangannya. Namun seringkali perusahaan dalam melakukannya hanya bersifat kualitatif intuitif, serta tidak dapat dijabarkan secara kuantitatif dan sistematis.

Proses perbaikan kualitas jasa penerbangan perusahaan dilakukan berdasarkan atribut-atribut jasa pelayanan yang diberikan oleh perusahaan penerbangan kepada customer. Informasi mengenai atribut–atribut jasa tersebut diperoleh dari data preferensi dan persepsi customer terhadap atribut–atribut dari perusahaan penerbangan. Data tersebut diolah dengan metode Quality Function Deployment (QFD) dengan harapan dapat memberikan informasi, dan langkah antisipasi yang perlu dilakukan Lion Air mengenai kondisi persaingan yang ada.

Kualitas pelayanan Lion Air saat ini masih kurang memuaskan jika dibandingkan dengan apa yang diharapkan oleh pengguna jasa/ penumpangnya. Hal ini terbukti dari nilai gap kepuasan dari atribut yang diteliti bernilai negatif. Kebijakan yang dapat dilakukan oleh Maskapai penerbangan Lion Air dalam meningkatkan layanan adalah Perawatan dan pemeliharaan pesawat secara rutin dan berkala, Pemberian reward dan punish pada karyawan, Pelatihan peningkatan keahlian, Penambahan armada baru, Kebersihan dan kerapian pesawat
Numerical Analysis of Soil Improvement for a Foundation of a Factory Using Stone Columns Made of Different Types of Coarse-grained Materials
Authors: Stacho Jakub , Sulovska Monika
Published: July 2019

Stone columns made of coarse-grained materials and crushed stone are one of the most-used technologies for soil improvement all over the world. Stone columns improve the strength and deformation properties of subsoil and reduce the time required for the consolidation of fine-grained soils. The impact of the improvement depends on the properties of the original subsoil as well as the properties of the coarse-grained materials used for the stone columns. The article deals with the effects of the properties of coarse-grained materials for stone columns on the settlement and consolidation times of improved subsoil for the foundation of a factory. Numerical modeling as a 2D task was performed using Plaxis geotechnical software. The numerical analysis included two methods of modeling stone columns in a plane strain model, i.e., one method often used by practical engineers in the region of Slovakia, and one modified method, which allowed for a more accurate determination of the final settlement and consolidation time. The method modeled stone columns as continuous walls, and the compaction of the soil between the stone columns was taken into account. The results showed that the type of coarse-grained material can significantly affect the final settlement and time of consolidation. Stone columns made of quarry stone were suitable in the given geological conditions regardless of the design of the mesh, while stone columns made of pebble gravel were suitable only with a mesh of 1.5 x 1.5 m.
Keikutsertaan Pasangan Usia Subur Menjadi Akseptor KB Desa Ujung Payung Kecamatan Payung Kabupaten Karo
Authors: Brahmana Netti Etalia Br
Published: July 2019

Laju pertumbuhan  penduduk yang masih tinggi merupakan suatu fenomena yang memerlukan penanganan yang serius dari masyarakat dan pemerintah.  Pada tahun 2012 jumlah penduduk indonesia sebesar 230 juta jiwa dan meningkat pada tahun 2013 menjadi 250 juta jiwa. Salah satu penyebab masih tingginya laju pertumbuhan  tersebut dikarenakan masih ada Pasangan Usia Subur (PUS) yang tidak menggunakan alat kontrasepsi. Jenis penelitian ini menggunakan analitik dengan desain cross sectional yang bertujuan untuk mengetahui faktor-faktor yang mempengaruhi keikutsertaan PUS menjadi akseptor KB di Desa Ujung Payung Kecamatan Payung Kabupaten Karo Tahun 2015. Populasi dalam penelitian ini seluruh PUS yang ada di Desa Ujung Payung pada Tahun 2015 sebanyak 140 orang dan keseluruhannya dijakan sebagai sampel. Analisa data digunakan dengan analisis univariat, bivariat dan multivariat. Hasil penelitian yang diperoleh univariat: mayoritas responden berumur 20-35 tahun (74 orang), pendidikan menengah (77 orang), paritas ≤ 3 (73 orang) dan jenis kelamin anak perempuan (93 orang), bivariat: semua variabel berpengaruh terhadap keikutsertaan PUS menjadi akseptor KB, umur (p value 0,002), pendidikan (p value 0,000), paritas (p value 0,000), pengetahuan (p value 0,000), sikap (p value 0,001), dukungan tenaga kesehatan (p value 0,001 ) dan multivariat: yang paling dominan berpengaruh adalah pengetahuan.   Diharapkan  kepada petugas lapangan keluarga berencana agar lebih memperhatikan pasangan usia subur untuk meningkatkan pengetahuan tentang keluarga berencana
Analisis Penghematan Biaya Klaim Kesehatan PT. XYZ sebagai Upaya Peningkatan Keselamatan dan Kesehatan Kerja
Authors: Khoirin Isna Auliana , Amalia Fitri , Saputra Nano , Kusumo Ryan Tejo , Ariyani Nova , Widiyatmoko Ryan Yudo
Published: July 2019

PT. XYZ merupakan suatu perusahaan swasta yang bergerak di bidang industri farmasi. Rata-rata angka kejadian kecelakaan kerja dan penyakit akibat kerja pada perusahaan tersebut pada tahun 2013-2016 mencapai 92 kejadian per tahun dan mengakibat biaya klaim kesehatan sebesar Rp 125.221.840 (per tahun). Untuk melindungi keselamatan tenaga kerja guna mewujudkan produktiitas kerja yang optimal diselenggarakan upaya keselamatan dan kesehatan kerja serta diadakannya jaminan sosial bagi pekerja. Selama tahun 2017 PT. XYZ menyelenggarakan BPJS Ketenagakerjaan bagi pekerjanya, setelah empat tahun terakhir mengeluarkan dana yang besar untuk biaya klaim kesehatan pekerjanya. Penelitian ini bertujuan untuk mengetahui penghematan biaya klaim kesehatan PT. XYZ setelah melaksanakan BPJS Ketenagakerjaan. Dari penelitian dengan mengunakan metode yuridis-empiris dan juga kuantitatif, didapatkan hasil biaya klaim Kesehatan PT. XYZ terjadi penurunan Rp 77.334.058 atau eisiensi mencapai 23,64%. Masih ada kecelakaan kerja atau penyakit akibat kerja sebesar 63 kejadian. PT. XYZ perlu mengadakan APD terutama masker, sarung tangan, helm pelindung dan sepatu safety serta perlu diadakan sosialisasi mengenai pentingnya SMK3.
Kualitas Kerja Bidan dalam Program Pencegahan Penularan HIV Ibu ke Anak di Kota Depok
Authors: Rosiana Hani , Jayatmi Irma
Published: July 2019

Angka prevalensi dan penularan HIV dari ibu ke bayi masih terbatas, jumlah ibu hamil yang terinfeksi HIV cenderung meningkat. Infeksi HIV dari ibu ke anak dapat dicegah, melalui upaya pencegahan penularan  dari ibu ke anak. Penelitian ini bertujuan  untuk  mengetahui  kualitas kerja bidan dalam program pencegahan penularan HIV ibu ke anak di Kota Depok tahun 2017. Metode yang digunakan dalam penelitian ini adalah menggunakan metode penelitian kuantitatif, desain penelitian cross sectional dan metode SEM. Sampel dari penelitian ini sebesar 65 orang. Data yang digunakan dalam penelitian ini adalah data primer dengan instrumen  penelitian berupa kuesioner. Hasil penelitian menunjukan bahwa pengaruh langsung antara dukungan oganisasi terhadap kualitas kerja bidan sebesar -39,76%. Lingkungan kerja berpengaruh secara langsung terhadap kualitas kerja bidan sebesar 83,23%. Sarana dan prasarana berpengaruh secara langsung terhadap kualitas kerja bidan sebesar 11,89%. Demikian juga untuk variabel persepsi berpengaruh secara langsung terhadap kualitas kerja bidan sebesar 22,69%. Nilai Q square adalah 82,25% dan sisanya sebesar 17,75% dijelaskan variabel lain yang tidak ada dalam penelitian ini. Dapat disarankan bahwa Dinas kesehatan dan kepala Puskesmas berperan aktif untuk memberikan konseling dan informasi tentang program pencegahan penularan HIV ibu ke anak serta mengevaluasi secara berkelanjutan sehingga dapat mengetahui sampai dimana kekurangan bidan dalam melaksanakan
Pengaruh Pengetahuan Perawat, Ability dan Budaya Kerja terhadap Kinerja Perawat Pelaksana di Rawat Inap Rumah Sakit Umum 2 Kata Kunci Pengetahuan, Ability, budaya, kinerja perawat. ABSTRACT Daerah Al Ihsan Bandung
Authors: Meilirianta Meilirianta , Haizurrachman Haizurrachman
Published: July 2019

RSUD Al Ihsan Bandung,   memiliki sarana pelayanan  yang memadai, dan petugas yang  profesional, juga berkualitas pelayanan yang bermutu,  tetapi belum optimal. Perawat pelaksana dalam melaksanakan tugasnya harus mampu  memuaskan   setiap   pemakai jasa   pelayanan.   Kenyataannya ada beberapa perawat tidak melaksanakan tugas   asuhan. Desain   penelitian   cross sectional, data diolah dengan SmartPLS untuk membuktikan   hipotesis pada   2 variabel  laten yang memiliki  3 - 4 indikator yang mempengaruhi  variabel ability dan kinerja serta  mencari besaran  hubungan  antara variabel tersebut (nilai rho),  terbentuk persamaan matematis. Sampel 125 responden diambil secara random sampling. Pengambilan informasi melalui kuesioner. Hasil penelitian menunjukan semua indikator berpengaruh secara langsung, (23.3 %) dari semua variabel yang terdapat pada  model itu.  Sedangkan  pengaruh paling besar adalah budaya terhadap ability sebesar 44.9 %. Jadi variabel budaya sangat tinggi dengan nilai koeisien  sebesar 0.319 dan  signiikan pada 5 % (nilai Thitung    = 5.708 > ttabel   1.96). Saran perawat pelaksana diharap dapat meningkatan budaya keramahan dan suka menolong pada perawat  pelaksana karena  memiliki kelebihan dalam pelayanan di ruang rawat inap pada  kinerja perawat pelaksana  di Rawat Inap RSUD Al Ihsan Bandung.
Ціннісні виклики адміністративно-процедурного законодавства
Authors: ВДОВІЧЕН ВІТАЛІЙ , ПОДОРОЖНА ТЕТЯНА
Published: July 2019

У статті розглянуто питання прийняття кодифікованого акта про адмі ністративні процедури як нового етапу у розвитку процесуального законодавства, що встановлює певні правові порядки у вирішенні адміністративних спорів (справ, що виникають з адміністративних та інших публічних правовідносин). Наголошено, що в цій сфері адміністративних правовідносин, на жаль, існує “нереалізований потенціал” Конституції України щодо створення адміністративно-процедурної форми здійснення публічного управління. Це засвідчують, зокрема, прогалини в системі адміністративно-правової регламентації відносин щодо прийняття адміністративних актів; суперечності процесу поліпшення адміністративно-процесуального законодавства; зрештою, відставання у розвитку адміністративно-правової теорії від сформованих у європейських країнах підходів, принципів і пріоритетів дослідницької діяльності в галузі юридизації публічного управління та правового оформлення взаємодії адміністративних органів і громадян щодо забезпечення їхніх прав і законних інтересів. І це в той час, коли потреба в задоволенні прав і законних інтересів осіб під час взаємодії з владними органами передбачає чітко визначені принципи і правила, які й утворюють адміністративну процедуру. Метою статті є аналіз сформованих у доктрині адміністративного права з урахуванням законодавчих і практичних аспектів підходів до прийняття адміністративного процедурного кодексу як базового нормативно-правового акта з регулювання надання адміністративних послуг органами виконавчої влади та місцевого самоврядування. Зроблено висновок, що завдяки прийняттю адміністративно-процедурного кодексу вдасться: встановити належний порядок здійснення адміністративних дій у межах однієї з найважливіших правових форм публічного управління; сформувати основу для ефективного забезпечення прав, свобод і законних інтересів громадян та організацій, що взаємодіють із публічною владою та її органами; надати адміністративному правовому регулюванню управлінських відносин належної системності і повноцінної структурованості; не тільки гармонізувати внутрішню структуру механізму адміністративно-правового регулювання, а й створити основу для ефективного судового захисту в адміністративних справах, тобто забезпечити правильне і законне вирішення адміністративних та інших публічних спорів; вирішити встановлені Кодексом адміністративного судочинства України (КАС України) завдання адміністративного судочинства на всіх етапах цього виду реалізації судової влади. Дія такого кодексу забезпечить подальший розвиток адміністра тивнопроцесуальної форми, основні контури якої сьогодні зафіксовані в КАС України, та, безумовно, створить можливості для формування нових наукових уявлень і теоретичної моделі адміністративного процесу як судового процесу.
Правова природа патронатної служби
Authors: КОЛПАКОВ ВАЛЕРІЙ , КОЛОМОЄЦЬ ТЕТЯНА
Published: July 2019

Серед інституціональних складових службового права (державна служба, служба в органах місцевого самоврядування, дисциплінарна відповідальність, заохочення по службі тощо) важливе місце посідає інститут патронатної служби. Він є системною складовою публічної служби відповідної галузі законодавства.
Метою статті є встановлення і висвітлення правової природи відносин патронатної служби як базового підґрунтя для уточнення їх місця в предметі адміністративного і службового права, співвідношення з державною службою і службою в органах місцевого самоврядування, критеріїв визначення переліку посад працівників, які виконують функції з обслуговування, перспектив адаптації до європейських стандартів і принципів.
Для її досягнення у статті досліджені погляди вчених-адміністративістів на правову природу, поняття, принципи, сучасний стан і перспективи розвитку патронатної служби, представлені у публікаціях, які умовно можна поділяти, по-перше, на такі, де патронатна служба розглядається у контексті дослідження інших інституцій службового права; по-друге, спеціально присвячені питанням патронатної служби. Проаналізовані положення основних нормативних документів, які здійснювали регулюючий вплив на становлення і розвиток патронатної служби в Україні.
У результаті здійсненого дослідження автори вважають, що є підстави: а) визнати патронатну службу необхідним ресурсом забезпечення ефективності функціонування відповідних категорій публічних службовців; б) правовим засобом гарантування еволюційного розвитку правових та організаційних засад службових відносин; в) належним інструментом становлення політично неупередженої, професійної, ефективної, орієнтованої на громадян публічної служби, яка функціонувала б в інтересах держави і суспільства; г) відносини патронатної служби регулюються нормами службового права, яке, зі свого боку, є підгалуззю права адмі ністративного.
Звідси випливає, що патронатна служба має адміністративно-правову природу. Вона являє собою законодавчо виокремлену систему юридичних норм, якими забезпечується цілісне регулювання окремого різновиду службових відносин, тобто має свій предмет регулювання. Це свідчення того, що патронатна служба є інститутом службового права.
Концептуалізація освітнього права як підгалузі адміністративного права України
Authors: МОСЬОНДЗ СЕРГІЙ
Published: July 2019

На сучасному етапі розвитку українського суспільства констатується факт відсутності концептуального уявлення про освітнє право. Питання про правову природу освітнього права є досить складним і багато в чому суперечливим. Сьогод ні, з приводу названої галузі права, науковці висловлюють досить різні погляди щодо його місця у системі вітчизняного права, які зводяться переважно до того, що освітнє право є або комплексною галуззю права, або самостійною галуззю права. Викладене обумовлює необхідність формулювання завершеної та досконалої теорії освітнього права.
Мета статті – через призму аналізу норм чинного законодавства, а також критичного вивчення праць сучасних учених сформулювати авторську концепцію освітнього права як підгалузі адміністративного права України.
Досягнення сформульованої мети здійснюється за допомогою комплексного та послідовного застосування відповідного наукового інструментарію, представленого такими методами наукового пізнання: логіко-семантичним, системним, структурнологічним, методами групування, дедукції, індукції, аналізу та синтезу тощо.
Проведено аналіз наукових доробків, присвячених з’ясуванню підстав виокремлення освітнього права у системі права України. Вдалося встановити, що виокремлення освітнього права за предметом і методом правового регулювання не лише ускладнює його розуміння у національній системі права, а й створює проблеми у сфері правотворчої та правозастосовної діяльності. На думку автора, для вирішення цього завдання за основу виділення освітнього права в системі права України необхідно взяти напрям функціонування публічної адміністрації. А оскільки публічна адміністрація може функціонувати лише у чітко визначеному напрямі з обов’язковим дотриманням положень чинного законодавства, то його норми утворюють підгалузь особливого адміністративного права.
Зроблено висновок, що в Україні сформована система нормативних актів, покликаних регулювати порядок організації та діяльності суб’єктів публічної адміністрації, спрямованої на реалізацію державної політики у сфері освіти. Виконуючи названі завдання, публічна адміністрація тим самим сприяє забезпеченню та реалізації права на дошкільну, повну загальну середню, позашкільну, професійно-тех-нічну, вищу і післядипломну освіту, зафіксованого у ст. 53 Конституції України. Сукупність таких правових норм й об’єднується у рамках освітнього права, сформованого у межах особливого адміністративного права України.
Specialties of the structure and conductivity of the non-aqueous electrolytes based on alkali metal bis (salicyl) borates and bis (oxalate) borates
Authors: Diamant Viktor , Trachevskii Volodymyr , Pershina Katherine , Ogenko Volodymyr , Donchu Chen , Huawen Hu , Min Chen , Xiaowen Wang , Menglei Chang
Published: July 2019

The structure and coordination environment of non-aqueous electrolytes based on bis(salicyl)borates of lithium, sodium, potassium, tetramethylammonium (MeBSB) and bis(oxalato)borates from lithium to cesium (MeBOB) using NMR spectroscopy have been investigated. Bis(salicyl)borates (BSB) and bis(oxalate)borates (BOB) of alkali metals and organic cations are considered as promising electroconductive components of electrolytes of modern chemical sources of current (lithium, sodium ion batteries and super-capacitors). The salts were synthesized by the microwave radiation method. The 13C and 11B NMR spectra analysis determined the presence of symmetric structure in BOB anion and the presence of two optical conformations of the BSB anion with labile coordination environment of boron. The conformations of the BSB are the result of the ion contact pairs formation. In the case of tetramethylammonium cation the presence of conformations are depended on the reactive medium.

The conformational lability of the coordination sphere of NaBSB dissolved in DMAA is connected with increasing of the integral intensity of carboxyl group singles relatively signals of carbon atoms in fragments of another functional affiliation when the time delay between radio frequencies varies within 2-15 seconds. The difference in the structure of these anions leads to a change in the thermal dependence of the electrical conductivity of BSB and the transport of ions in non-aqueous solvents. Maximum electrical conductivity of salt solutions in DMFA is achieved at close concentrations of 0.75 m for KBSB and 0.77-1 m for NaBSB. The solubility of BSB is better than the BOB. Based on the measurements of the conductivity and the data of electrochemical impedance spectroscopy (the angle of inclination of spectra in the Nyquist coordinates in the low frequency range, the phase angle shift at a frequency) it was proposed the existence of two ways of ions and charge transfer in the electrolytes: diffusion and relay transport. The possibility of formation of a labile salt complex with a solvent due to hydrogen bonds is established.
Impact of Agroecological Practices on Greenhouse Vegetable Production: Comparison among Organic Production Systems
Authors: Ciaccia Corrado , Ceglie Francesco Giovanni , Burgio Giovanni , Madžarić Suzana , Testani Elena , Muzzi Enrico , Mimiola Giancarlo , Tittarelli Fabio
Published: July 2019

In greenhouses, where intensive systems are widely used for organic production, the differences between “conventionalized” and agroecological approaches are especially evident. Among the agronomic practices, green manure from agroecological service crops (ASCs) and organic amendments represent the main tools for soil fertility management with respect to the substitution of synthetic fertilizer with organic ones (the input substitution approach). Over a two-year organic rotation, we compared a conventionalized system (SB) and two agroecological systems, characterized by ASC introduction combined with the use of manure (AM) and compost (AC) amendments. A system approach was utilized for the comparison assessment. For this purpose, agronomic performance, soil fertility and the density of soil arthropod activity were monitored for the entire rotation. The comprehensive evaluation of the parameters measured provided evidence that clearly differentiated SB from AM and AC. The drivers of discrimination were soil parameters referring to long term fertility and soil arthropod dynamics. The study confirmed the higher productivity of SB but also no positive impact on soil fertility and soil arthropods, as highlighted by AM and AC. Based on the results, a trade-off between productivity and the promotion of long-term ecosystem diversity and functioning is needed for the assessment of systems of organic production.
Discrimination of Tomato Plants (Solanum lycopersicum) Grown under Anaerobic Baffled Reactor Effluent, Nitrified Urine Concentrates and Commercial Hydroponic Fertilizer Regimes Using Simulated Sensor Spectral Settings
Authors: Sibanda Mbulisi , Mutanga Onisimo , Magwaza Lembe S. , Dube Timothy , Magwaza Shirly T. , Odindo Alfred O. , Mditshwa Asanda , Mafongoya Paramu L.
Published: July 2019

We assess the discriminative strength of three different satellite spectral settings (HyspIRI, the forthcoming Landsat 9 and Sentinel 2-MSI), in mapping tomato (Solanum lycopersicum Linnaeus) plants grown under hydroponic system, using human-excreta derived materials (HEDM), namely, anaerobic baffled reactor (ABR) effluent and nitrified urine concentrate (NUC) and commercial hydroponic fertilizer mix (CHFM) as main sources of nutrients. Simulated spectral settings of HyspIRI, Landsat 9 and Sentinel 2-MSI were resampled from spectrometric proximally sensed data. Discriminant analysis (DA) was applied in discriminating tomatoes grown under these different nutrient sources. Results showed that the simulated spectral settings of HyspIRI sensor better discriminate tomatoes grown under different fertilizer regimes when compared to Landsat 9 OLI and Sentinel-2 MSI spectral configurations. Using the DA algorithm, HyspIRI exhibited high overall accuracy (OA) of 0.99 and a kappa statistic of 0.99 whereas Landsat OLI and Sentinel-2 MSI exhibited OA of 0.94 and 0.95 and 0.79 and 0.85 kappa statistics, respectively. Simulated HyspIRI wavebands 710, 720, 690, 840, 1370 and 2110 nm, Sentinel 2-MSI bands 7 (783 nm), 6 (740 nm), 5 (705 nm) and 8a (865 nm) as well as Landsat bands 5 (865 nm), 6 (1610 nm), 7 (2200 nm) and 8 (590 nm), in order of importance, were selected as the most suitable bands for discriminating tomatoes grown under different fertilizer regimes. Overall, the performance of simulated HyspIRI, Landsat 9 OLI-2 and Sentinel-2 MSI spectral bands seem to bring new opportunities for crop monitoring.
Comparative Epidemiology and Resistance Trends of Proteae in Urinary Tract Infections of Inpatients and Outpatients: A 10-Year Retrospective Study
Authors: Gajdács Márió , Urbán Edit
Published: July 2019

Compared with infections caused by other bacterial pathogens, urinary tract infections (UTIs) caused by Proteae are often more severe and associated with a higher rate of recurrence, sequelae, and pyelonephritis. The aim of this retrospective study was to assess and compare the prevalence of UTIs caused by different species of the Proteae tribe (namely Proteus, Morganella and Providencia species) and the antibiotic resistance levels isolated from inpatients and outpatients in a primary- and tertiary-care teaching hospital in the Southern Great Plain of Hungary, during a 10-year study period. To evaluate the resistance trends of isolated strains, amoxicillin/clavulanic acid, ceftriaxone, meropenem, ertapenem, gentamicin, ciprofloxacin, and fosfomycin were chosen as indicator antibiotics, based on local antibiotic utilization data. Members of Proteae were more frequently isolated in the case of inpatients (7.20 ± 1.74% vs. 5.00 ± 0.88%; p = 0.0031), P. mirabilis was the most frequently isolated member of the group. The ratio of resistant strains to sulfamethoxazole/trimethoprim, ciprofloxacin, ceftriaxone, and fosfomycin was significantly higher in the inpatient group. In the case of amoxicillin/clavulanic acid, ceftriaxone, ciprofloxacin, and sulfamethoxazole/trimethoprim, the ratio of resistant isolates was markedly higher between 2013–2017 (p < 0.01). Resistance developments of Proteae, coupled with their intrinsic non-susceptibility to several antibiotics (tetracyclines, colistin, nitrofurantoin) severely limits the number of therapeutic alternatives, especially for outpatients.
CP-SSD: Context Information Scene Perception Object Detection Based on SSD
Authors: Jiang Yun , Peng Tingting , Tan Ning
Published: July 2019

Single Shot MultiBox Detector (SSD) has achieved good results in object detection but there are problems such as insufficient understanding of context information and loss of features in deep layers. In order to alleviate these problems, we propose a single-shot object detection network Context Perception-SSD (CP-SSD). CP-SSD promotes the network’s understanding of context information by using context information scene perception modules, so as to capture context information for objects of different scales. Deep layer feature map used semantic activation module, through self-supervised learning to adjust the context feature information and channel interdependence, and enhance useful semantic information. CP-SSD was validated on benchmark dataset PASCAL VOC 2007. The experimental results show that, compared with SSD, the mean Average Precision (mAP) of the CP-SSD detection method reaches 77.8%, which is 0.6% higher than that of SSD, and the detection effect was significantly improved in images with difficult to distinguish the object from the background.
Review of Machining Equipment Reliability Analysis Methods based on Condition Monitoring Technology
Authors: Dai Wei , Sun Jiahuan , Chi Yongjiao , Lu Zhiyuan , Xu Dong , Jiang Nan
Published: July 2019

The condition of mechanical equipment during machining is closely related to the accuracy and roughness of the workpiece. In an intelligent sensing environment, a large amount of multi-source data reflecting status information are generated during processing, and a number of studies have been conducted for machining equipment reliability analysis. In this paper, the reliability analysis method of machining equipment based on condition monitoring technology is taken as the main line. And an up-to-date comprehensive survey of multi-source information during the cutting process, failure physical analysis for signal selection and reliability assessment based on condition information will be provided. Finally, the future challenges and trends will also be presented. It is a feasible and valuable research direction to evaluate the reliability of machining equipment for product quality characteristics.
Recent Progress of Metal–Air Batteries—A Mini Review
Authors: Wang Chunlian , Yu Yongchao , Niu Jiajia , Liu Yaxuan , Bridges Denzel , Liu Xianqiang , Pooran Joshi , Zhang Yuefei , Hu Anming
Published: July 2019

With the ever-increasing demand for power sources of high energy density and stability for emergent electrical vehicles and portable electronic devices, rechargeable batteries (such as lithium-ion batteries, fuel batteries, and metal–air batteries) have attracted extensive interests. Among the emerging battery technologies, metal–air batteries (MABs) are under intense research and development focus due to their high theoretical energy density and high level of safety. Although significant progress has been achieved in improving battery performance in the past decade, there are still numerous technical challenges to overcome for commercialization. Herein, this mini-review summarizes major issues vital to MABs, including progress on packaging and crucial manufacturing technologies for cathode, anode, and electrolyte. Future trends and prospects of advanced MABs by additive manufacturing and nanoengineering are also discussed.
Prediction of Surface Treatment Effects on the Tribological Performance of Tool Steels Using Artificial Neural Networks
Authors: Cavaleri Liborio , Asteris Panagiotis G. , Psyllaki Pandora P. , Douvika Maria G. , Skentou Athanasia D. , Vaxevanidis Nikolaos M.
Published: July 2019

The present paper discussed the development of a reliable and robust artificial neural network (ANN) capable of predicting the tribological performance of three highly alloyed tool steel grades. Experimental results were obtained by performing plane-contact sliding tests under non-lubrication conditions on a pin-on-disk tribometer. The specimens were tested both in untreated state with different hardening levels, and after surface treatment of nitrocarburizing. We concluded that wear maps via ANN modeling were a user-friendly approach for the presentation of wear-related information, since they easily permitted the determination of areas under steady-state wear that were appropriate for use. Furthermore, the achieved optimum ANN model seemed to be a simple and helpful design/educational tool, which could assist both in educational seminars, as well as in the interpretation of the surface treatment effects on the tribological performance of tool steels.
A Brief Theoretical Analysis on the Ventilation Characteristics of the Multi-Intake-Well Air Supply System in a Spillway Tunnel
Authors: Lian Jijian , Ren Panhong , Qi Chunfeng , Liu Fang , Ouyang Qunan
Published: July 2019

It is of great significance to study the ventilation characteristics of air supply systems in spillway tunnels, especially for high dams. In this paper, a brief theoretical approach to evaluate the ventilation characteristics of a multi-intake-well air supply system was established, which was mainly derived from the Bernoulli equation and continuity equation. With this approach, an analysis of the ventilation characteristics of the Jinping-I project spillway tunnel was carried out. A comparison of the theoretical results and prototype data suggested the theoretical approach to be valid and practical. The value of the drag coefficient at the air-water interface should be calibrated before evaluation because the drag coefficient is crucial for the accuracy of theoretical results. In addition, the influences of certain structural factors of the spillway tunnel and air intake well on the ventilation characteristics of multi-intake-well air supply systems are investigated.
Estimation of Turbulence Parameters in the Lower Troposphere from ShUREX (2016–2017) UAV Data
Authors: Luce Hubert , Kantha Lakshmi , Hashiguchi Hiroyuki , Lawrence Dale
Published: July 2019

Turbulence parameters in the lower troposphere (up to ~4.5 km) are estimated from measurements of high-resolution and fast-response cold-wire temperature and Pitot tube velocity from sensors onboard DataHawk Unmanned Aerial Vehicles (UAVs) operated at the Shigaraki Middle and Upper atmosphere (MU) Observatory during two ShUREX (Shigaraki UAV Radar Experiment) campaigns in 2016 and 2017. The practical processing methods used for estimating turbulence kinetic energy dissipation rate ε and temperature structure function parameter C T 2 from one-dimensional wind and temperature frequency spectra are first described in detail. Both are based on the identification of inertial (−5/3) subranges in respective spectra. Using a formulation relating ε and C T 2 valid for Kolmogorov turbulence in steady state, the flux Richardson number R f and the mixing efficiency χ m are then estimated. The statistical analysis confirms the variability of R f and χ m around ~ 0.13 − 0.14 and ~ 0.16 − 0.17 , respectively, values close to the canonical values found from some earlier experimental and theoretical studies of both the atmosphere and the oceans. The relevance of the interpretation of the inertial subranges in terms of Kolmogorov turbulence is confirmed by assessing the consistency of additional parameters, the Ozmidov length scale L O , the buoyancy Reynolds number R e b , and the gradient Richardson number Ri. Finally, a case study is presented showing altitude differences between the peaks of N 2 , C T 2 and ε , suggesting turbulent stirring at the margin of a stable temperature gradient sheet. The possible contribution of this sheet and layer structure on clear air radar backscattering mechanisms is examined.
Historical Winter Storm Atlas for Germany (GeWiSA)
Authors: Jung Christopher , Schindler Dirk
Published: July 2019

Long-term gust speed (GS) measurements were used to develop a winter storm atlas of the 98 most severe winter storms in Germany in the period 1981–2018 (GeWiSa). The 25 m × 25 m storm-related GS fields were reconstructed in a two-step procedure: Firstly, the median gust speed ( G S ˜ ) of all winter storms was modeled by a least-squares boosting (LSBoost) approach. Orographic features and surface roughness were used as predictor variables. Secondly, the quotient of GS related to each winter storm to G S ˜ , which was defined as storm field factor (STF), was calculated and mapped by a thin plate spline interpolation (TPS). It was found that the mean study area-wide GS associated with the 2007 storm Kyrill is highest (29.7 m/s). In Southern Germany, the 1999 storm Lothar, with STF being up to 2.2, was the most extreme winter storm in terms of STF and GS. The results demonstrate that the variability of STF has a considerable impact on the simulated GS fields. Event-related model validation yielded a coefficient of determination (R2) of 0.786 for the test dataset. The developed GS fields can be used as input to storm damage models representing storm hazard. With the knowledge of the storm hazard, factors describing the vulnerability of storm exposed objects and structures can be better estimated, resulting in improved risk management.
tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis
Authors: Shen Linyuan , Tan Zhendong , Gan Mailin , Li Qiang , Chen Lei , Niu Lili , Jiang Dongmei , Zhao Ye , Wang Jinyong , Li Xuewei , Zhang Shunhua , Zhu Li
Published: July 2019

tRNA-derived fragments (tRFs), a novel type of non-coding RNA derived from tRNAs, play an important part in governing gene expressions at a post-transcriptional level. To date, the regulatory mechanism of tRFs governing fat deposition and adipogenesis is completely unknown. In this study, high fat diet was employed to induce an obese rat model, and tRFs transcriptome sequencing was conducted to identify differentially expressed tRFs that response to obesity. We found out that tRFGluTTC, which promoted preadipocyte proliferation by increasing expressions of cell cycle regulatory factors, had the highest fold change in the 296 differentially expressed tRFs. Moreover, tRFGluTTC also suppressed preadipocyte differentiation by reducing triglyceride content and lipid accumulation, and by decreasing expressions of genes that related to fatty acid synthesis. According to results of luciferase activity analysis, tRFGluTTC directly targeted Kruppel-like factor (KLF) 9, KLF11, and KLF12, thus significantly suppressing mRNA expressions of these target genes. Moreover, tRFGluTTC suppressed adipogenesis, accompanying by suppressing expressions of adipogenic transcription factors (aP2, PPARγ, and C/EBPα). In conclusion, these results imply that tRFGluTTC may act as a novel epigenetic molecule regulating adipogenesis and could provide a new strategy for the intervention treatment of obesity.
Fabrication of Human Keratinocyte Cell Clusters for Skin Graft Applications by Templating Water-in-Water Pickering Emulsions
Authors: Celik Sevde B. G. , Dominici Sébastien R. , Filby Benjamin W. , Das Anupam A. K. , Madden Leigh A. , Paunov Vesselin N.
Published: July 2019

Most current methods for the preparation of tissue spheroids require complex materials, involve tedious physical steps and are generally not scalable. We report a novel alternative, which is both inexpensive and up-scalable, to produce large quantities of viable human keratinocyte cell clusters (clusteroids). The method is based on a two-phase aqueous system of incompatible polymers forming a stable water-in-water (w/w) emulsion, which enabled us to rapidly fabricate cell clusteroids from HaCaT cells. We used w/w Pickering emulsion from aqueous solutions of the polymers dextran (DEX) and polyethylene oxide (PEO) and a particle stabilizer based on whey protein (WP). The HaCaT cells clearly preferred to distribute into the DEX-rich phase and this property was utilized to encapsulate them in the water-in-water (DEX-in-PEO) emulsion drops then osmotically shrank to compress them into clusters. Prepared formulations of HaCaT keratinocyte clusteroids in alginate hydrogel were grown where the cells percolated to mimic 3D tissue. The HaCaT cell clusteroids grew faster in the alginate film compared to the individual cells formulated in the same matrix. This methodology could potentially be utilised in biomedical applications.
Infants’ Individuation of Faces by Gender
Authors: Pickron Charisse B. , Cheries Erik W.
Published: July 2019

By 3 months of age, infants can perceptually distinguish faces based upon differences in gender. However, it is still unknown when infants begin using these perceptual differences to represent faces in a conceptual, kind-based manner. The current study examined this issue by using a violation-of-expectation manual search individuation paradigm to assess 12- and 24-month-old infants’ kind-based representations of faces varying by gender. While infants of both ages successfully individuated human faces from non-face shapes in a control condition, only the 24-month-old infants’ reaching behaviors provided evidence of their individuating male from female faces. The current findings help specify when infants begin to represent male and female faces as being conceptually distinct and may serve as a starting point for socio-cognitive biases observed later in development.
From Extinction Learning to Anxiety Treatment: Mind the Gap
Authors: Carpenter Joseph K. , Pinaire Megan , Hofmann Stefan G.
Published: July 2019

Laboratory models of extinction learning in animals and humans have the potential to illuminate methods for improving clinical treatment of fear-based clinical disorders. However, such translational research often neglects important differences between threat responses in animals and fear learning in humans, particularly as it relates to the treatment of clinical disorders. Specifically, the conscious experience of fear and anxiety, along with the capacity to deliberately engage top-down cognitive processes to modulate that experience, involves distinct brain circuitry and is measured and manipulated using different methods than typically used in laboratory research. This paper will identify how translational research that investigates methods of enhancing extinction learning can more effectively model such elements of human fear learning, and how doing so will enhance the relevance of this research to the treatment of fear-based psychological disorders.
A New Analytical Prediction for Energy Responses of Hemi-Cylindrical Shells to Explosive Blast Load
Authors: Liu Ping , Xu Ning , Pan Zhi-Hong
Published: July 2019

This study presents a new analytical model on the dissipation process of the initial total energy of the hemi-cylindrical shell subjected to the explosive blast load. The analytical formulation has been established using the energy method. The analytical predictions have been validated and found to be in excellent agreement with numerical simulations calculated by explicit finite element method (via LS-DYNA). The variational parameters considered are the shell thickness, elastic modulus, densities of the shell, and the positions of the detonation. Considering varieties of the parameters, the analytical and numerical results demonstrate that the pattern of vibrating deformations can be classified into two types according to the detonation positions. If the detonation position was at the midpoint of the width, there was no main frequency, whilst if the detonation position was at the edge of the width, the shell vibrated with a main frequency. It was also found from both analytical and numerical models that the total initial energy is inversely proportional to the thickness of the shell ( T ), namely, the exact formula can be written as β = ρ a c / ρ s T . Surprisingly, this study is the first to highlight that the total energy decreases with time by the exponential function, and the exponential ratio ( β ) is inversely proportional to the thickness of the shell as well.
Prognostic Role of miR-221 and miR-222 Expression in Cancer Patients: A Systematic Review and Meta-Analysis
Authors: Ravegnini Gloria , Cargnin Sarah , Sammarini Giulia , Zanotti Federica , Bermejo Justo Lorenzo , Hrelia Patrizia , Terrazzino Salvatore , Angelini Sabrina
Published: July 2019

Background: A wealth of evidence has shown that microRNAs (miRNAs) can modulate specific genes, increasing our knowledge on the fine-tuning regulation of protein expression. miR-221 and miR-222 have been frequently identified as deregulated across different cancer types; however, their prognostic significance in cancer remains controversial. In view of these considerations, we performed an updated systematic review and meta-analysis of published data investigating the effects of miR-221/222 on overall survival (OS) and other secondary outcomes among cancer patients. A systematic search of PubMed, Web of Knowledge, and Cochrane Library databases was performed. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were used to assess the strength of association. Results: Fifty studies, analyzing 6086 patients, were included in the systematic review. Twenty-five studies for miR-221 and 17 studies for miR-222 which assessed OS were included in the meta-analysis. High expression of miR-221 and miR-222 significantly predicted poor OS (HR: 1.48, 95% CI: 1.14–1.93, p = 0.003 and HR: 1.90, 95% CI: 1.43–2.54, p < 0.001, respectively). Subgroup analysis revealed that the finding on miR-221 was not as robust as the one on miR-222. Furthermore, high miR-222 expression was also associated with worse progression-free survival and disease-free survival pooled with recurrence-free survival. Conclusions: The meta-analysis demonstrated that high expression of miR-222 is associated with poor prognosis in cancer patients, whereas the significance of miR-221 remains unclear. More work is required to fully elucidate the role of miR-221 and miR-222 in cancer prognosis, particularly in view of the limitations of existing results, including the significant heterogeneity and limited number of studies for some cancers.
Functional Toll-Like Receptors (TLRs) Are Expressed by a Majority of Primary Human Acute Myeloid Leukemia Cells and Inducibility of the TLR Signaling Pathway Is Associated with a More Favorable Phenotype
Authors: Brenner Annette K. , Bruserud Øystein
Published: July 2019

Acute myeloid leukemia (AML) is a highly heterogeneous disease with regard to biological characteristics and receptor expression. Toll-like receptors (TLRs) are upstream to the transcription factor NFκB and part of the innate immune system. They are differentially expressed on AML blasts, and during normal hematopoiesis they initiate myeloid differentiation. In this study, we investigated the response upon TLR stimulation in an AML cohort (n = 83) by measuring the increase of NFκB-mediated cytokine secretion. We observed that TLR4 is readily induced in most patients, while TLR1/2 response was more restricted. General response to TLR stimulation correlated with presence of nucleophosmin gene mutations, increased mRNA expression of proteins, which are part of the TLR signaling pathway and reduced expression of transcription-related proteins. Furthermore, signaling via TLR1/2 appeared to be linked with prolonged patient survival. In conclusion, response upon TLR stimulation, and especially TLR1/2 induction, seems to be part of a more favorable phenotype, which also is characterized by higher basal cytokine secretion and a more mature blast population.