bluuebunny/crossref_metadata_2025 huggingface dataset:
Congenital Anomalies Presenting as Head-Neck Swellings: A Study of 50 Cases
Authors: Islam Md Zahidul , Rahman Md Abdur , Mahfuz Md Sirajul Islam
Published: February 2020

Purpose: To analyse the prevalence, distribution and presentation of different congenital head-neck lesions with their age, sex, site and side predilection.
Methods: 50 patients of head-neck congenital swelling was selected from january/2013 upto december/2013 in the OPD of otorhino-laryngology, head and neck deptt. of Dhaka medical college hospital under a specific prospective study protocol.
Results: The most frequent swelling was thyroglossal cyst(42%), followed by branchial arch anomalies (18%),dermoid cyst(14%),pre-auricular sinus(14%),lymphangioma(8%) and haemangioma(4%).Amongst the cervical swellings the sequential preponderence was thyroglossal cyst(52%),branchial arch anomalies(23%),dermoid cyst(13%), lymphangioma(10%) and haemangioma (2%).The majority of branchial arch anomalies(100%) were of second arch. The majority of patients were of first(52%) and second(30%) decade and the male to female ratio for thyroglossal cysts was 1:1.1.The majority of lesions were painless swelling and all were surgically excised.
Conclusion: The overall frequency and age-sex distribution of congenital head-neck swellings as well as site, nature and type specific predominance of some of them in OPD of Dhaka medical college hospital are almost similar to international findings.
Bangladesh J Otorhinolaryngol; October 2017; 23(2): 171-179
Sociodemographic characteristics of the patients of Tonsillitis attended in OPD of a district level Hospital
Authors: Mahfuz Md Sirajul Islam , Kabir Md Ahmedul
Published: February 2020

Aim: To find out the tonsillitis patients and also find out its sociodemographic characteristics in district level of Bangladesh.
Method: This was a prospective cross sectional study, which was carried in out patients of tonsillitis attended in OPD of 250 Bedded General Hospital, Gopalganj. All the patients of acute tonsillitis, chronic tonsillitis and adenoid hypertrophy were selected from OPD irrespective of sex during the period of July 2015 to June 2016. Age ranges from 0-90 years and person residents of Gopalganj and adjacent districts.
Result: In this study 45.54% were male and 54.46% were female. Male female ratio 1:1.2.Majority of patients were age group 0-15 years (55.97%) Mean age of patient 45 years. Maximum family had monthly income TK 10,000 to 20,000 and maximum patients were dependent (30%) 5-6 family members were highest group, 60% patients lived in katcha house, 75% lived in rural area 35% patients used to bath in pond and majority of patients primary and JSC qualification. The majority of signs and symptoms were sore throat (100%), red, swollen tonsil (26%); white pus filled spots on the tonsil (38%); swollen lymph node in neck (60%) and bad breath (halitosis) (38%).
Conclusion: Tonsillitis is still high in rural area of our country and commonly found in younger age group. Thus improvement of related socioeconomic factors, health awareness campaign, improved health education and early accessibility can reduce the incidence of disease.
Bangladesh J Otorhinolaryngol; October 2017; 23(2): 180-186
Surgical Outcomes of Chronic Suppurative Otitis Media
Authors: Hossain Mohammad Delwar , Islam Mohammed Sirazul , Hossain Md Zakir , Kamal Kazi Mostafa , Alam Md Monjurul
Published: February 2020

Objectives: The purpose of this study is to observe the surgical outcomes of chronic suppurative otitis media. 1. To assess the result of surgical procedure to obtain dry and safe ears. 2. To assess the hearing levels after surgery. 3. To observe the complications that occur during the operation and in the immediate postoperative period
Methods: A total 60 patients with CSOM (active squamous variety) who underwent tympanomastoid surgery studied in a period of 1 year from July 2013 to June 2014 at CMH Dhaka.
Results: The maximum patients were from15-24 years (35%) age group, male to female ratio was 1.2:1. Highest number of patients (39%) was from middle class family. All the 60 patients presented with discharge from ear and hearing impairment. Maximum (40%) were with attic and postero-superior marginal perforation along with granulation tissue. In 1stpost op month,53 (88.33%) manifested dry ear and in 3rd month after operation 52 (90%) patients manifested dry ear. 7 (11.66%) patients showed discharge from the ear after 1st month which decreased to the 0% after 3rd month. Graft was taken successfully in 56 (93.33%) patients after the first month of operation which reduced to 51 (85%) after third month of operation. Hearing status of the patients before operation proclaimed that 48% patients suffered from moderate hearing loss, 22% and 17% patients suffered from mild and moderately severe loss respectively. 13% patients suffered from severe hearing loss After surgery 86% patients’ condition was improved, 4% patients’ condition deteriorated and 10% patients’ condition remain unchanged . The mean preoperative air-bone gap was 32.10 dB and mean postoperative air-bone gap was 19.10 dB .
Bangladesh J Otorhinolaryngol; October 2017; 23(2): 187-194
A Case of Primary tuberculosis of the tongue mimicking malignancy
Authors: Islam Muhammad Nazrul , Khan Md Mesbah Uddin , Biswas Mohammad Asaduzzaman , Showkath Mohammad Shohel
Published: February 2020

Tuberculosis of the tongue is a very rare event even in a areas and countries in which tuberculosis is endemic. The disease can present itself in a variety of clinical appearances, most of which may mimic malignant lingual neoplasm’s clinically. Here we report a case of lingual non healing ulcer in a 44 years female which was clinically suspected as malignant ulcer. The diagnosis of lingual tuberculosis was made by histopathology.
Bangladesh J Otorhinolaryngol; October 2017; 23(2): 199-202
Huge Intramuscular Cavernous Hemangioma involving SCM, Trapezius and scalene anterior: A Case Report
Authors: Biswas Akhil Chandra , Chowdhuri Nazmul Hossain , Ahmed Feroz , Milki Fariduddin , Mohammad Tareq , Rahman ASM Lutfur
Published: February 2020

Intramuscular hemangiomas are rare benign neoplasms accounting for <1% of all hemangiomas and <20% are found in head and neck area. The muscle most frequently involved is the masseter muscle and very few cases have been reported for the occurrence of these hemangioma in the Sternocleidomastoid, trapezius muscle and scalene anterior muscles. Here, we are presenting a case report of intramuscular hemangioma involving these muscles in a 10-years-old boy.
Bangladesh J Otorhinolaryngol; October 2017; 23(2): 203-207
Combination Difference Synchronization between Identical Generalised Lotka-Volterra Chaotic Systems
Authors: Trikha P. , - Nasreen , Jahanzaib L. S.
Published: February 2020

This manuscript investigates the combination difference synchronization between identical Generalised Lotka-Volterra Chaotic Systems. Numerical Simulations have been performed which are in complete agreement of theoretical results.
Short-Chain Alcohols Upregulate GILZ Gene Expression and Attenuate LPS-Induced Septic Immune Response
Authors: Ng Hang Pong , Wang Yubo , Jennings Scott , Nelson Steve , Wang Guoshun
Published: February 2020

Alcohol differentially affects human health, depending on the pattern of exposure. Moderate intake provides beneficial mood modulation and an anti-inflammatory effect, while excessive consumption leads to immunosuppression and various alcohol use disorders. The mechanism underlying this bi-phasic action mode of alcohol has not been clearly defined. Our previous publication demonstrated that ethanol, in the absence of glucocorticoids (GCs), induces expression of Glucocorticoid-Induced Leucine Zipper (GILZ), a key molecule that transduces GC anti-inflammatory effect through a non-canonical activation of glucocorticoid receptor (1). Here we report that similar short-chain alcohols, such as ethanol, propanol and isopropanol, share the same property of upregulating GILZ gene expression, and blunt cell inflammatory responsein vitro. When mice were exposed to these alcohols, GILZ gene expression in immune cells was augmented in a dose-dependent manner. Monocytes and neutrophils were most affected. The short-chain alcohols suppressed host inflammatory response to lipopolysaccharide (LPS) and significantly reduced LPS-induced mortality. Intriguingly, propanol and isopropanol displayed more potent protection than ethanol at the same dose. Inhibition of ethanol metabolism enhanced the ethanol protective effect, suggesting that it is ethanol, not its derivatives or metabolites, that induces immune suppression. Taken together, short-chain alcoholsper seupregulate GILZ gene expression and provide immune protection against LPS toxicity, suggesting a potential measure to counter LPS septic shock in a resource limited situation.
Change of Price Premiums Trend for Organic Food Products: The Example of the Polish Egg Market
Authors: Pawlewicz Adam
Published: February 2020

One of the most rapidly growing areas of the organic agricultural system is egg production. However, the price premium often decreases the affordability of organic foods. In this study, the production and sales of organic eggs in Europe were compared, the prices of organic and conventional eggs in Poland were analyzed, and the price premium on the Polish market was evaluated. This study relied on data of Eurostat, Statistics Poland, Agricultural and Food Quality Inspection and Ministry of Agriculture and Rural Development in Poland. The prices of organic and conventional eggs on the Polish wholesale market were analyzed based on the monthly price registers. The production and sales of organic eggs in Europe were characterized by a steady increase. The nominal and real prices of organic eggs were higher than the prices of conventional eggs throughout the entire analyzed period. The nominal prices of organic eggs tended to decrease. However, an upward trend was observed in the real prices of both organic and conventional eggs. The average price premium for organic eggs exceeded 128% (median of 121%). The price premium was characterized by moderate variation (Vc = 33%). In Poland, the price premium was on a downward trend by around 1% per month in the examined period.
Plant Acceptance for Oviposition of Tetranychus urticae on Strawberry Leaves Is Influenced by Aromatic Plants in Laboratory and Greenhouse Intercropping Experiments
Authors: Hata Fernando Teruhiko , Béga Vinádio Lucas , Ventura Maurício Ursi , Grosso Francine dos Santos , Silva José Eduardo Poloni da , Machado Renato Ribeiro , Sousa Virgínia
Published: February 2020

The objective was to evaluate aromatic plants’ effects on the acceptance, preference, egg load, and life span of females of the twospotted spider mite (TSSM) in laboratory experiments and TSSM population under aromatic plants’ intercropping in greenhouse experiments. The pseudofruits production was also evaluated. For the laboratory, basil’s, Chinese chives’, chives’, and garlic’s influence on TSSM were tested on strawberry leaves. Four laboratory experiments were conducted: (1) Multiple choice test; (2) T-shaped arena test; (3) host–plant acceptance on aromatic plant or strawberry leaves; and (4) performance of TSSMs on strawberry leaves under aromatic plant influence. For the greenhouse experiments, assessments of the TSSM populations were realized by observing TSSM with a 10× magnifying glass on strawberry leaves in a monocrop or intercropped with Chinese chives, chives, garlic, or onion. Pseudofruit production was evaluated. Our results show that strawberry leaves were strongly preferred by TSSM. The T-shaped arena test revealed that all aromatic plants repel the TSSM. The test with the performance of TSSM females revealed that aromatic plants affected the mite’s biological parameters. Chinese chives reduced the number of eggs laid per day by 33.22%, whereas garlic reduced the number by 17.30% and chives reduced it by 12.46%. The total number of eggs was reduced by 34.79% with Chinese chives and 25.65% with garlic. Greenhouse experiments showed that chives reduced TSSM populations on two cycles and Chinese chives and garlic reduced TSSM populations on the first cycle only. With our findings, we suggest that Chinese chives, chives, and garlic are the primary candidates for intercropping use against TSSM. Chinese chives and garlic reduced the total number of eggs, but only garlic reduced female mite longevity. However, none of the intercropping plants improved strawberry pseudofruit production.
Towards a Sustainable Agriculture: Strategies Involving Phytoprotectants against Salt Stress
Authors: Acosta-Motos José Ramón , Penella Consuelo , Hernández José A. , Díaz-Vivancos Pedro , Sánchez-Blanco María Jesús , Navarro Josefa María , Gómez-Bellot María José , Barba-Espín Gregorio
Published: February 2020

Salinity is one of the main constraints for agriculture productivity worldwide. This important abiotic stress has worsened in the last 20 years due to the increase in water demands in arid and semi-arid areas. In this context, increasing tolerance of crop plants to salt stress is needed to guarantee future food supply to a growing population. This review compiles knowledge on the use of phytoprotectants of microbial origin (arbuscular mycorrhizal fungi and plant growth-promoting rhizobacteria), osmoprotectants, melatonin, phytohormones and antioxidant metabolism-related compounds as alleviators of salt stress in numerous plant species. Phytoprotectants are discussed in detail, including their nature, applicability, and role in the plant in terms of physiological and phenotype effects. As a result, increased crop yield and crop quality can be achieved, which in turn positively impact food security. Herein, efforts from academic and industrial sectors should focus on defining the treatment conditions and plant-phytoprotectant associations providing higher benefits.
Effect of Droplet Size Parameters on Droplet Deposition and Drift of Aerial Spraying by Using Plant Protection UAV
Authors: Chen Shengde , Lan Yubin , Zhou Zhiyan , Ouyang Fan , Wang Guobin , Huang Xiaoyu , Deng Xiaoling , Cheng Shengnan
Published: February 2020

In the field of pesticide spraying, droplet size is one of the most important factors affecting droplet deposition and drift. In order to study the effect of different droplet size parameters on droplet deposition distribution and drift of aerial spraying by using plant protection UAV, an aerial spraying test with the same spraying rate and different size droplets in rice canopy was carried out by using multi-rotor unmanned aerial vehicles (UAV) and four TEEJET nozzles with different orifice sizes (these droplets with a volume median diameter (VMD) of 95.21, 121.43, 147.28, and 185.09 μm, respectively), and the deposition distribution and penetration of droplets in the target area and the drift distribution of droplets in the non-target area were compared and analyzed. The results showed that the deposition distribution and penetration of droplets in the target area and the drift distribution of droplets in the non-target area were influenced by the droplet size. The droplet deposition rate in the upper and lower rice canopies were increased in the target area with the increase of droplet size. The penetration results of droplets also increased with the increase of droplet size, and that of droplets with a VMD of 185.09 μm was the best, reaching 38.13%. The average values of the cumulative drift rate of droplets in the rice canopy in the four tests were 73.87%, 50.26%, 35.91%, and 23.06%, respectively, and the cumulative drift rate and the drift distance of droplets decreased with the increase of droplet size, which indicated that the increase of droplet size can effectively reduce droplet drift. It demonstrated that the droplet size is one of the most important factors affecting droplet deposition and drift for pesticide spraying by plant protection UAV, and for the application of plant protection UAV with extra-low volume spraying, the use of droplets with VMD less than 160 μm should be avoided and a more than 10 m buffer zone should be considered downwind of the spraying field to avoid drug damage caused by pesticide drift. The results have fully revealed the effect of droplet size parameters on droplet deposition and drift of aerial spraying. Moreover, the influence of the wind field below the rotors on the distribution of droplet deposition was surmised and analyzed from the perspective of plant protection UAV. It is important for optimizing the droplet parameters of aerial spraying, increasing the spraying efficiency, and realizing precision agricultural aviation spray.
Appraisal of Combined Applications of Trichoderma virens and a Biopolymer-Based Biostimulant on Lettuce Agronomical, Physiological, and Qualitative Properties under Variable N Regimes
Authors: Rouphael Youssef , Carillo Petronia , Colla Giuseppe , Fiorentino Nunzio , Sabatino Leo , El-Nakhel Christophe , Giordano Maria , Pannico Antonio , Cirillo Valerio , Shabani Edris , Cozzolino Eugenio , Lombardi Nadia , Napolitano Mauro , Woo Sheridan L.
Published: February 2020

The current research elucidated the agronomical, physiological, qualitative characteristics and mineral composition of lettuce (Lactuca sativa L. var. longifolia) after treatments with a beneficial fungus Trichoderma virens (TG41) alone or in combination with a vegetal biopolymer-based biostimulant (VBP; ‘Quik-link’). The experiment consisted of lettuce plants grown in three N conditions: sub-optimal (0N kg ha−1), optimal (70N kg ha−1), and supra-optimal (140N kg ha−1) N levels. Lettuce grown under 0N fertilization showed a significant increase in fresh yield when inoculated with TG41 alone (45%) and a greater increase with TG41 + VBP biostimulant (67%). At 48 days after transplanting, both the TG41 alone or TG41+VBP biostimulant induced higher values of CO2 assimilation in comparison to the control. The mineral concentrations in leaf tissues were greater by 10% for K and 12% for Mg with the TG41+VBP treatments compared to the untreated lettuce. The lettuce plants receiving either TG41 alone or TG41+VBP biostimulants had a significantly lower nitrate content than any of the untreated controls. In non-fertilized conditions, plants treated with TG41+VBP biostimulants produced lettuce of higher premium quality as indicated by the higher antioxidant activity, total ascorbic acid (+61%–91%), total phenols (+14%) and lower nitrate content when compared to the untreated lettuce.
Acquiring Plant Features with Optical Sensing Devices in an Organic Strip-Cropping System
Authors: Krus Anne , van Apeldoorn Dirk , Valero Constantino , Ramirez Juan José
Published: February 2020

The SUREVEG project focuses on improvement of biodiversity and soil fertility in organic agriculture through strip-cropping systems. To counter the additional workforce a robotic tool is proposed. Within the project, a modular proof of concept (POC) version will be produced that will combine detection technologies with actuation on a single-plant level in the form of a robotic arm. This article focuses on the detection of crop characteristics through point clouds obtained with two lidars. Segregation in soil and plants was successfully achieved without the use of additional data from other sensor types, by calculating weighted sums, resulting in a dynamically obtained threshold criterion. This method was able to extract the vegetation from the point cloud in strips with varying vegetation coverage and sizes. The resulting vegetation clouds were compared to drone imagery, to prove they perfectly matched all green areas in said image. By dividing the remaining clouds of overlapping plants by means of the nominal planting distance, the number of plants, their volumes, and thereby the expected yields per row could be determined.
Risk Management Tools for Sustainable Agriculture: A Model for Calculating the Average Price for the Season in Revenue Insurance for Citrus Fruit
Authors: Mateos-Ronco Alicia , Server Izquierdo Ricardo J.
Published: February 2020

Risk management in agriculture is at the heart of major reforms in many OECD countries and European agricultural policies. Price risks, which are generally not insurable per se, have been covered by the Common Agricultural Policy (CAP), which has been shaped as a system of protection against market shocks and an instrument for income stabilization. However, there is an increasing propensity to combine the use of public and private risk management tools as well. In Spain, revenue insurance has not yet developed in the same way as other risk coverage insurance, although it is an upcoming target of agricultural insurance policies with the aim of ensuring income stability for agricultural producers. This paper presents the results of the methodology used to draw up a composition index or model of the average price for the season or representative market field price to be used for revenue insurance purposes in citrus fruit. High explanatory power regression models and the analytic hierarchy process (AHP) were used. The results show that the average price for the season obtained reliably represents the market field prices in the country’s various producer areas.
Evaluating a Controlled-Release Fertilizer for Plant Establishment in Floating Elements for Bioretention Ponds
Authors: Zanin Giampaolo , Maucieri Carmelo , Dal Ferro Nicola , Bortolini Lucia , Borin Maurizio
Published: February 2020

In bioretention ponds proposed to manage urban runoff, floating elements with anchored macrophytes plants improve nutrient and pollutants removal and provide aesthetic benefits. To prompt the establishment and initial growth of plants in floating elements with substrate, the application of Osmocote (a controlled-release fertilizer) in tablet form was proposed. In a confined environment, eight treatments were compared, combining two substrates (peat and zeolite at a ratio of 1:1 or 2:1 v/v), two levels of fertilization (without or with addition of Osmocote plus tablets; 5 g plant−1), and the presence or absence of Mentha aquatica L. plants. For about 16 weeks, the amount and quality of water, along with plant growth and nutrient content, were monitored. The results showed better plant growth when Osmocote was supplied, with no effect of the substrate. The presence of the plant produced the almost total uptake of the nutrients contained in the tap water and released by the fertilizer. This indicates that the use of a controlled release fertilizer can improve plant growth without compromising water quality, hence being a valuable solution to promote plant establishment usable as routine practice when a bioretention basin is vegetated with floating elements with substrate.
Safety of Oilseed Rape Straw Mulch of Different Lengths to Rice and Its Suppressive Effects on Weeds
Authors: Zhu Jinwen , Liang Wen , Yang Siyu , Wang Huifu , Shi Chunhua , Wang Shuo , Zhou Weijun , Lu Qiang , Islam Faisal , Xu Weidong , DiTommaso Antonio
Published: February 2020

Rice is widely grown after harvesting of oilseed rape (Brassica napus L.) in many countries. Experiments were carried out under greenhouse and field conditions to assess the impact of oilseed rape straw mulch on rice and paddy weeds. Oilseed rape mulch (900 g m−2) from straw 1-to-7 cm long was found to be safe for rice, when applied four days after sowing (DAS) in direct-seeded rice or four days after transplanting (DAT). In the meantime, the biomass of Echinochloa crus-galli (L.) P. Beauv. was reduced 65.74%, 80.18%, 81.15%, 70.99%, 55.65%, and 27.22%, respectively, when mulched with powder, and 1, 3, 5, 7, and 9-cm long oilseed rape straw, respectively, and the biomass reductions in Leptochloa chinensis (L.) Nees., Ludwigia prostrata Roxb., Ammannia auriculata Willd., and Cyperus difformis L. were all above 97% when mulched with 1 cm-length straw. The results of a field trial confirmed that oilseed rape straw mulch (900 g m−2) of 1 cm length was safe for rice. Moreover, weed suppression was as effective as the standard herbicide (oxadiargyl + butachlor 525 g ai ha−1) treatment. These findings demonstrate the potential to manage paddy rice weeds in an effective and environmentally sound manner by mulching with the straw of a preceding crop, oilseed rape.
The Role of Information and Interaction Processes in the Adoption of Agriculture Inputs in Uganda
Authors: Freeman Kathlee , Qin Hua
Published: February 2020

Agriculture is an essential component of food security, sustainable livelihoods, and economic development in sub-Saharan Africa (SSA). Smallholder farmers, however, are restricted in the number of crops they can grow due to small plot sizes. Agriculture inputs, such as fertilizers, herbicides or pesticides, and improved seed varieties, could prove to be useful resources to improve yield. Despite the potential of these agriculture technologies, input use throughout much of SSA remains low. This paper aims to better understand the process of innovation diffusion through information and interaction processes at the individual, social network, and community levels. A total of 203 participants were surveyed using a semi-structured interview method in four rural communities located in the Mbale, Lira, Kabale, and Masaka districts of Uganda. Participants were asked about their access to information technologies, information sources via social network ties, level of engagement in the local community, and agricultural input use. Results indicate households with higher levels of information access through cell phone use and weak-tie information sources are more likely to use inputs. Significant findings also include the interactional effect of cell phones and weak ties on fertilizer adoption. This research could inform policy makers of cost-effective methods of disseminating agriculture information and encouraging innovation diffusion.
Overexpression of Nepenthesin HvNEP-1 in Barley Endosperm Reduces Fusarium Head Blight and Mycotoxin Accumulation
Authors: Bekalu Zelalem Eshetu , Krogh Madsen Claus , Dionisio Giuseppe , Bæksted Holme Inger , Jørgensen Lise Nistrup , S. Fomsgaard Inge , Brinch-Pedersen Henrik
Published: February 2020

Fusarium head blight (FHB) causes substantial losses of yield and quality in grains, both in the field and in post-harvest storage. To date, adequate natural genetic resistance is not available for the control of FHB. This study reports the cloning and overexpression of a barley (Hordeum vulgare L.) antifungal gene, nepenthesin 1 (HvNEP-1), in the endosperm of barley grains. Transgenic barley lines overexpressing HvNEP-1 substantially reduced FHB severity and disease progression after inoculation with Fusarium graminearum or Fusarium culmorum. The transgenic barley also showed reduced accumulation of the mycotoxin deoxynivalenol (DON) in grain, far below the minimum value allowable for food. Semi-field evaluation of four HvNEP-1 transgenic lines revealed substantial reduction of FHB severity and progression as compared with the control H. vulgare cultivar Golden promise (GP) plants. Our study demonstrated the utility of HvNEP-1 for the control of FHB in barley, and possibly other grains such as wheat and maize.
Identification and Characterization of White Grape Varieties Autochthonous of a Warm Climate Region (Andalusia, Spain)
Authors: Sancho-Galán Pau , Amores-Arrocha Antonio , Palacios Víctor , Jiménez-Cantizano Ana
Published: February 2020

The high sensitivity of one of the most important crops in the world, such as vine (Vitis vinifera L.), to particular changes caused by the phenomena associated with global warming, is encouraging the wine industry to place value on grape varieties that are autochthonous to each production area. These are generally conserved in germplasm banks and may pose a useful tool to counteract the effects of climate change. In order to determine the actual resource that such varieties constitute, this research has carried out a genetic identification, a morphological characterization, and an analysis of the grape musts obtained from four autochthonous varieties (Cañocazo, Castellano, Mantúo de Pilas, and Palomino Fino). This genetic analysis has allowed the identification of autochthonous varieties with different genotypes. However, all of them had similar phenotypic characteristics in terms of high hair density in adult leaves. With respect to the physicochemical composition of the musts, significant differences have been observed between the autochthonous varieties, with respect to the control variety of Palomino Fino. Nevertheless, all of them have exhibited an adequate physicochemical composition to produce quality white wines. For all of the above reasons, these local varieties should be considered suitable for cultivation in areas with warmer and drier climates, such as Andalusia (Spain).
From Smart Farming towards Agriculture 5.0: A Review on Crop Data Management
Authors: Saiz-Rubio Verónica , Rovira-Más Francisco
Published: February 2020

The information that crops offer is turned into profitable decisions only when efficiently managed. Current advances in data management are making Smart Farming grow exponentially as data have become the key element in modern agriculture to help producers with critical decision-making. Valuable advantages appear with objective information acquired through sensors with the aim of maximizing productivity and sustainability. This kind of data-based managed farms rely on data that can increase efficiency by avoiding the misuse of resources and the pollution of the environment. Data-driven agriculture, with the help of robotic solutions incorporating artificial intelligent techniques, sets the grounds for the sustainable agriculture of the future. This paper reviews the current status of advanced farm management systems by revisiting each crucial step, from data acquisition in crop fields to variable rate applications, so that growers can make optimized decisions to save money while protecting the environment and transforming how food will be produced to sustainably match the forthcoming population growth.
Efficiency of an Integrated Purification System for Pig Slurry Treatment under Mediterranean Climate
Authors: Terrero Martire Angélica , Muñoz María Ángeles , Faz Ángel , Gómez-López María Dolores , Acosta Jose A.
Published: February 2020

The intensification of pig production is considered a risky activity for the environment when the generated pig slurry is not adequately treated. In addition, intensive agriculture practices where pig slurry is applied to the cropland could cause nitrate leaching, salinization, and soil pollution (heavy metals and pathogens), thus the development of an eco-friendly system for pig slurry treatment is essential to avoid undesirable environmental impacts. The main objective of this study was to assess the efficiency of an integrated purification system (IPS) for treating pig slurry. The system included a pretreatment module (raw pig slurry tank, phase separator, aeration tank, and settlement tank), constructed wetlands (CWs) that included an unplanted cell and a planted cell, and a storage pond (SP). Pig slurry samples from the pretreatment modules, CWs, and SP were collected in triplicate and physic-chemical and microbial analyses were performed. Results showed that the pretreatment modules decreased the total suspended solids (TSS), total nitrogen (TN), and total phosphorus (TP) concentrations in the liquid fraction. Higher total nitrogen removal was reported in the planted cell, which decreased from 4.0 g L−1 to 1.9 g L−1 in the inflow and outflow, respectively. Total efficiencies over 85% were found in the planted and unplanted cells for TSS, Kjeldahl nitrogen (KN), chemical oxygen demand (COD), and TP. Microbial parameters were eliminated after the treatment in the planted cell. Therefore, the results indicated that filtration (pretreatment), purification (constructed wetland), and bioremediation (storage pond) constituted an appropriate IPS for treating pig slurry.
Korean Wild Soybeans (Glycine soja Sieb & Zucc.): Geographic Distribution and Germplasm Conservation
Authors: Nawaz Muhammad , Lin Xiao , Chan Ting-Fung , Ham Junghee , Shin Tai-Sun , Ercisli Sezai , Golokhvast Kirill , Lam Hon-Ming , Chung Gyuhwa
Published: February 2020

Domesticated crops suffer from major genetic bottlenecks while wild relatives retain higher genomic diversity. Wild soybean (Glycine soja Sieb. & Zucc.) is the presumed ancestor of cultivated soybean (Glycine max [L.] Merr.), and is an important genetic resource for soybean improvement. Among the East Asian habitats of wild soybean (China, Japan, Korea, and Northeastern Russia), the Korean peninsula is of great importance based on archaeological records, domestication history, and higher diversity of wild soybeans in the region. The collection and conservation of these wild soybean germplasms should be put on high priority. Chung’s Wild Legume Germplasm Collection maintains more than 10,000 legume accessions with an intensive and prioritized wild soybean germplasm collection (>6000 accessions) guided by the international code of conduct for plant germplasm collection and transfer. The center holds a library of unique wild soybean germplasms collected from East Asian wild habitats including the Korean mainland and nearby islands. The collection has revealed interesting and useful morphological, biochemical, and genetic diversity. This resource could be utilized efficiently in ongoing soybean improvement programs across the globe.
Fungal Diseases in Two North-West Spain Vineyards: Relationship with Meteorological Conditions and Predictive Aerobiological Model
Authors: Cortiñas Rodríguez Jose A. , González-Fernández Estefanía , Fernández-González María , Vázquez-Ruiz Rosa A. , Aira María Jesús
Published: February 2020

Grey mould, powdery mildew, and downy mildew are the most frequent fungal diseases among vineyards worldwide. In the present study, we analysed the influence of the fungi causing these diseases (Botrytis, Erysiphe, and Plasmopara, respectively) on two viticulture areas from North-western (NW) Spain during three growth seasons (2016, 2017, and 2018). The obtained results showed the predominant concentration of the Botrytis airborne spores, mainly from the beginning of the Inflorescence emerge phenological stage (S-5) until the end of the Flowering phenological stage (S-6). Erysiphe and Plasmopara airborne spore peak concentrations were more localised around Flowering (S-6) and Development of fruits (S-7) phenological stages. We applied a Spearman’s correlation test and a Principal Component Analysis to determine the influence of the meteorological parameters on the concentration of airborne spores. Taking into account the variables with the highest correlation coefficient, we developed multiple regression models to forecast the phytopathogenic fungal spore concentrations. The Botrytis model regression equation explained between 59.4–70.9% of spore concentration variability. The Erysiphe equation explained between 57.6–61% and the Plasmopara explained between 39.9–55.8%. In general, we found better prediction results for mean daily concentrations than sporadic spore peaks.
Artificial Intelligence-Enabled Predictive Insights for Ameliorating Global Malnutrition: A Human-Centric AI-Thinking Approach
Authors: How Meng-Leong , Chan Yong Jiet
Published: February 2020

According to the World Health Organization (WHO) and the World Bank, malnutrition is one of the most serious but least-addressed development challenges in the world. Malnutrition refers to the malfunction or imbalance of nutrition, which could be influenced not only by under-nourishment, but also by over-nourishment. The significance of this paper is that it shows how artificial intelligence (AI) can be democratized to enable analysts who are not trained in computer science to also use human-centric explainable-AI to simulate the possible dynamics between malnutrition, health and population indicators in a dataset collected from 180 countries by the World Bank. This AI-based human-centric probabilistic reasoning approach can also be used as a cognitive scaffold to educe (draw out) AI-Thinking in analysts to ask further questions and gain deeper insights. In this study, a rudimentary beginner-friendly AI-based Bayesian predictive modeling approach was used to demonstrate how human-centric probabilistic reasoning could be utilized to analyze the dynamics of global malnutrition and optimize conditions for achieving the best-case scenario. Conditions of the worst-case “Black Swan” scenario were also simulated, and they could be used to inform stakeholders to prevent them from happening. Thus, the nutritional and health status of vulnerable populations could be ameliorated.
Brainstem Auditory Evoked Potentials in Raccoon Dogs (Nyctereutes procynoides)
Authors: Ștefănescu Raluca , Roman Constantin , Miron Liviu Dan , Solcan Gheorghe , Vulpe Vasile , Hrițcu Luminița Diana , Musteata Mihai
Published: February 2020

Raccoon dogs (Nyctereutes procynoides) are canids indigenous to Eastern Asia being one of the most invasive non-native animals in Europe and potential vectors for several hazardous parasitic and viral diseases. To present, there is a lack of studies regarding objective techniques used to appreciate the integrity and functionality of the nervous system in this species. Brainstem auditory evoked potentials (BAER) is a cost-effective, quick and noninvasive technique to assess the functionality of nervous system. The aim of the study is to provide reference values and evaluates the reliability of BAER recording with needle electrodes in clinically healthy raccoon dogs. Nine individuals were investigated for BAER under xylazine and ketamine general anesthesia. Four waves (I, II, III and V) were identified and evaluated for latencies, morphologically similarity to those previously reported for other species (dogs, horses, cats, and ferret). Our data can be used in further studies to asses objectively the auditory system function in raccoon dogs.
Glutamate Supply Reactivates Ovarian Function while Increases Serum Insulin and Triiodothyronine Concentrations in Criollo x Saanen-Alpine Yearlings’ Goats during the Anestrous Season
Authors: Meza-Herrera César A. , Vergara-Hernández Hector P. , Paleta-Ochoa Alicia , Álvarez-Ruíz Alma R. , Veliz-Deras Francisco G. , Arellano-Rodriguez Gerardo , Rosales-Nieto Cesar A. , Macias-Cruz Ulises , Rodriguez-Martinez Rafael , Carrillo Evaristo
Published: February 2020

The possible effect of glutamate supplementation upon ovarian reactivation and serum concentrations of insulin (INS) and triiodothyronine (T3) in anestrous yearling goats was evaluated. Goats (n = 32, 12 mo., 26° North, 1117 m) with a similar live weight (LW) and body condition score (BCS) were blood sampled twice per week for two weeks (2 × 1 week × 2 weeks) to confirm the anestrus status (<1 ng P4/mL; RIA). Thereafter, goats were randomly assigned to either 1) Glutamate (GLUT; n = 16, LW = 27.1 ± 1.09 kg, 3.5 ± 0.18 units, IV-supplemented with 7 mg of glutamate kg−1 LW), or 2) Control (CONT; n = 16; LW = 29.2 ± 1.09 kg; BCS = 3.5 ± 0.18, IV saline). During the treatment period, 16 goats (eight/group) were blood sampled twice per week for six weeks. Such serum samples (2 × 1 week × 6 weeks) were quantified by their P4 content to evaluate the ovarian-luteal activity, whereas a sample subset (1 × 1 week × 6 weeks) was used to quantify their INS & T3 content to evaluate their metabolic status. Neither LW (28.19 kg; p > 0.05) nor BCS (3.51 units; p > 0.05) differed between treatments. Goats depicting ovarian reactivation favored the GLUT group (50 vs. 12.5%; p < 0.05). Neither INS (1.72 ± 0.15 ng mL−1) nor T3 (2.32 ± 0.11 ng mL−1) differed between treatments, yet a treatment x time interaction regarding INS & T3 concentration across time favored (p < 0.05) the GLUT group. The results unveil exogenous glutamate as an interesting modulator not only of ovarian reactivation, but of metabolic hormone synthesis.
Acknowledgement to Reviewers of Antibodies in 2019
Authors: Antibodies Editorial Office
Published: February 2020

The editorial team greatly appreciates the reviewers who have dedicated their considerable time andexpertise to the journal’s rigorous editorial process over the past 12 months[...]
Ceftazidime/Avibactam and Ceftolozane/Tazobactam for Multidrug-Resistant Gram Negatives in Patients with Hematological Malignancies: Current Experiences
Authors: Criscuolo Marianna , Trecarichi Enrico Maria
Published: February 2020

Patients suffering from hematological malignancies are at high risk for severe infections, including in particular bloodstream infections, which represent one of the most frequent life-threatening complications for these patients, with reported mortality rates reaching 40%. Furthermore, a worrisome increase in antimicrobial resistance of Gram-negative bacteria (e.g., cephalosporin- and/or carbapenem-resistant Enterobacteriaceae and multidrug-resistant (MDR) Pseudomonas aeruginosa) involved in severe infectious complications among patients with hematological malignancies has been reported during the last years. The two novel combination of cephalosporins and β-lactamase inhibitors, ceftolozane/tazobactam and ceftazidime/avibactam, were recently approved for treatment of complicated intra-abdominal and urinary tract infections and nosocomial pneumonia and display activity against several MDR Gram-negative strains. Although not specifically approved for neutropenic and/or cancer patients, these drugs are used in this setting due to increasing rates of infections caused by MDR Gram-negative bacteria. The aim of this review is to describe the actual evidence from scientific literature about the “real-life” use of these two novel drugs in patients with hematological malignancies and infections caused by MDR Gram-negative bacteria.
Bacterial Biofilm and its Role in the Pathogenesis of Disease
Authors: Vestby Lene K. , Grønseth Torstein , Simm Roger , Nesse Live L.
Published: February 2020

Recognition of the fact that bacterial biofilm may play a role in the pathogenesis of disease has led to an increased focus on identifying diseases that may be biofilm-related. Biofilm infections are typically chronic in nature, as biofilm-residing bacteria can be resilient to both the immune system, antibiotics, and other treatments. This is a comprehensive review describing biofilm diseases in the auditory, the cardiovascular, the digestive, the integumentary, the reproductive, the respiratory, and the urinary system. In most cases reviewed, the biofilms were identified through various imaging technics, in addition to other study approaches. The current knowledge on how biofilm may contribute to the pathogenesis of disease indicates a number of different mechanisms. This spans from biofilm being a mere reservoir of pathogenic bacteria, to playing a more active role, e.g., by contributing to inflammation. Observations also indicate that biofilm does not exclusively occur extracellularly, but may also be formed inside living cells. Furthermore, the presence of biofilm may contribute to development of cancer. In conclusion, this review shows that biofilm is part of many, probably most chronic infections. This is important knowledge for development of effective treatment strategies for such infections.
Dendropanax morbifera Leaf Polyphenolic Compounds: Optimal Extraction Using the Response Surface Method and Their Protective Effects against Alcohol-Induced Liver Damage
Authors: Eom Taekil , Kim Kyeoung Cheol , Kim Ju-Sung
Published: February 2020

The response surface methodology was used to optimally extract the antioxidant substances from Dendropanax morbifera leaves. The central composite design was used to optimally analyze the effects of ethanol concentration, sample to solvent ratio, extraction temperature, and extraction time on the total flavonoids (TF) content, ferric reducing antioxidant power (FRAP), and Trolox equivalent antioxidant capacity (TEAC). All three parameters were largely influenced by the ethanol concentration and extraction temperature, while TEAC was also influenced by the sample to solvent ratio. The maximum values of TF content, FRAP, and TEAC were achieved under the following extraction conditions: 70% ethanol, 1:10 sample to solvent ratio, 80 °C, and 14 h. The D. morbifera leaf extracts (DMLE) produced under these optimum extraction conditions were investigated to determine their preventive effects on alcohol-induced liver injury. The DMLE was shown to prevent liver injury by scavenging the reactive oxygen species generated by alcohol. In addition, composition analysis of DMLE found high contents of chlorogenic acid and rutin that were determined to inhibit alcoholic liver injury. The findings of this study suggest that DMLE could prove useful as a functional food product supplement to prevent liver injury caused by excessive alcohol consumption.
Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway
Authors: Qi Lina , Jiang Jingle , Zhang Jingfei , Zhang Lili , Wang Tian
Published: February 2020

Pregnancy complications are associated with oxidative stress induced by accumulation of trophoblastic ROS in the placenta. We employed the human trophoblast HTR8/SVneo cell line to determine the effect of curcumin pre-treatment on H2O2-induced oxidative damage in HTR8/Sveo cells. Cells were pretreated with 2.5 or 5 μM curcumin for 24 h, and then incubated with 400 μM H2O2 for another 24 h. The results showed that H2O2 decreased the cell viability and induced excessive accumulation of reactive oxygen species (ROS) in HTR8/Sveo cells. Curcumin pre-treatment effectively protected HTR8/SVneo cells against oxidative stress-induced apoptosis via increasing Bcl-2/Bax ratio and decreasing the protein expression level of cleaved-caspase 3. Moreover, curcumin pre-treatment alleviated the excessive oxidative stress by enhancing the activity of antioxidative enzymes. The antioxidant effect of curcumin was achieved by activating Nrf2 and its downstream antioxidant proteins. In addition, knockdown of Nrf2 by Nrf2-siRNA transfection abolished the protective effects of curcumin on HTR8/SVneo cells against oxidative damage. Taken together, our results show that curcumin could protect HTR8/SVneo cells from H2O2-induced oxidative stress by activating Nrf2 signaling pathway.
Bridelia speciosa Müll.Arg. Stem bark Extracts as a Potential Biomedicine: From Tropical Western Africa to the Pharmacy Shelf
Authors: Mahomoodally Mohamad Fawzi , Sinan Kouadio Ibrahime , Bene Kouadio , Zengin Gokhan , Orlando Giustino , Menghini Luigi , Veschi Serena , Chiavaroli Annalisa , Recinella Lucia , Brunetti Luigi , Leone Sheila , Angelini Paola , Hubka Vit , Covino Stefano , Venanzoni Roberto , Picot-Allain Marie Carene Nancy , De Lellis Laura , Cama Alessandro , Cziáky Zoltán , Jekő József , Ferrante Claudio
Published: February 2020

Bridelia species have been used in traditional African medicine for the management of diverse human ailments. In the current work, the detailed phytochemical profiles of the extracts of the stem bark of B. speciosa were evaluated and the antioxidant and enzyme inhibitory properties of the extracts were assessed. The anti-bacterial and anti-mycotic effects of the extracts were evaluated against selected pathogen strains. Additionally, the anti-proliferative effects were studied on the liver cancer HepG2 cell line. Finally, the putative protective effects were assessed on isolated rat liver that was challenged with lipopolysaccharide (LPS). The results revealed the presence of 36 compounds in the ethyl acetate extract, 44 in the methanol extract, and 38 in the water extract. Overall, the methanol extract showed the highest antioxidant activity, particularly in LPS-stimulated rat liver. Additionally, this extract exerted the highest antimycotic effect on C. albicans, whereas the water extract showed a promising anti-proliferative effect on liver cancer HepG2 cells. The methanol extract was also the most active as enzyme inhibitor, against acetylcholinesterase and butyrylcholinesterase. The current study appraises the antioxidant and enzyme inhibition properties of B. speciosa methanol extract and showed that this specie could be a promising source of biologically active phytochemicals, with potential health uses.