bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of a super‐ductile polypropylene/polycarbonate blend with high heat resistance by using reactive plasticizer
Authors: Matsumoto Koji , Nagai Masahiro , Hamakawa Kohei , Nishitsuji Shotaro , Inoue Takashi
Published: November 2012

High‐performance blend of polypropylene (PP) and polycarbonate (PC) has not been explored. The difficulty is caused by the big differences in melt viscosity (PP: low viscosity vs. PC: high viscosity) and polarity (PP: nonpolar vs. PC: polar). We put forth a new approach using a reactive plasticizer which is preferentially soluble with PC and polymerizable by organic peroxide. As the plasticizer, diallyl phthalate and triallyl cyanurate (TAC) were used. By reactive extrusion of PP/PC/plasticizer/dicumyl peroxide (e.g., 80/14/6/0.12 wt. ratio), reaction‐induced phase decomposition took place in the dispersed PC particles to develop a regularly phase‐separated nanostructure and the graft copolymer of PP and polymerized plasticizer was in situ generated at the interface. The extruded blend showed an excellent ductile behavior with about 500%‐elongation at break. TAC was very effective to elevate the heat resistance. Then, a super‐ductile PP/PC blend with high heat resistance was successfully developed. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Effect of oleic acid content and chemical crosslinking on the properties of palm oil‐based polyurethane coatings
Authors: Velayutham T. S. , Abd Majid W. H. , Ng B. K. , Gan S. N.
Published: November 2012

Polyurethanes (PU) were prepared by reacting palm oil‐based polyols and aromatic diisocyanate (toluene 2, 4 diisocyanates). The content of oleic acid was varied in the polyester polyols and the hydroxyl value was fixed to be 140 mg KOH g−1. The NCO/OH ratios were varied to 1.2, 1.4, and 1.6. Crosslinking density of the PU was measured by swelling in toluene at room temperature. It was found that the crosslinking increased with decreasing oleic acid content and increasing NCO/OH ratio. The samples were assessed by thermogravimetric analysis, differential scanning calorimetric, and short‐term creep measurements. The highest rupture strength of the PU films was 36 MPa and thermostability improved as the oleic acid content and the NCO/OH ratios were increased in the sample. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Morphological Study of the Sinus Node and Its Artery in Yak
Authors: Duan Deyong , Yu Sijiu , Cui Yan
Published: November 2012

The sinus node of yak has been studied by the histological methods and transmission electron microscopy. The sinus node artery of yak was also determined by the injection‐corrosion casting technique, the angiography, and histological methods. The results showed that the sinus node of yak contained an extensive framework of collagen and two main type cells: pacemaker cells (P cells) and transitional cells (T cells). The P cells had a perinuclear clear zone, contained less myofibrils, and appeared smaller mitochondria than T cells. The T cells were longer and slender than P cells, and had a variety of shapes. At the periphery of sinus node there were many nerve fibers and ganglions. Gap junction did not reveal reaction with anti‐connexin43, but it was detected by electron microscopy in the central part of sinus node of yak. The sinus node artery of yak originated from left coronary artery more frequently (98%) than by right (2%). The artery located at the periphery of sinus node. It had an internal elastic membrane throughout its course, and a large nerve bundle was found running in a longitudinal direction. Anat Rec, 2012. © 2012 Wiley Periodicals, Inc.
Immunocytochemical Localization of the Translocase of the Outer Mitochondrial Membrane (Tom20) in the Human Cochlea
Authors: Balaker Ashley E. , Ishiyama Paul , Lopez Ivan A. , Ishiyama Gail , Ishiyama Akira
Published: November 2012

Mitochondrial degeneration in the inner ear is likely a contributing factor in age‐related hearing loss and other otopathologies such as Meniere's disease. Most mitochondrial proteins are synthesized in the cytosol and imported through the mitochondrial membranes by translocators. The translocase of the outer membrane (Tom) is the universal entry gate for all proteins that are imported into mitochondria. Altered function of the translocator could alter protein transport into the mitochondria, and disrupt function. In this study, we determined the immunolocalization of Tom20, a major mitochondrial protein import receptor, in microdissected human cochlea frozen sections obtained from postmortem autopsy and celloidin‐embedded archival specimens. We used affinity purified rabbit polyclonal antibodies against Tom20. We also determined the Tom20 immunolocalization in the mouse inner ear. In the human and mouse cochlea, Tom20 was ubiquitously distributed in the organ of Corti, allowing well‐delineated visualization of inner and outer hair cells. Tom20 immunoreactivity localized in the cytoplasm of spiral ganglia neurons. In the inner ear of aged subjects with Meniere's disease, there was decreased expression of Tom20. These results suggest that Tom20 can be used in the inner ear as a marker for mitochondrial protein import. Anat Rec, 2013. © 2012 Wiley Periodicals, Inc.
Neonatal Brainstem Function and 4‐Month Arousal‐Modulated Attention Are Jointly Associated With Autism
Authors: Cohen Ira L. , Gardner Judith M. , Karmel Bernard Z. , Phan Ha T. T. , Kittler Phyllis , Gomez Tina Rovito , Gonzalez Maripaz G. , Lennon Elizabeth M. , Parab Santosh , Barone Anthony
Published: November 2012

The authors evaluated the contribution of initially abnormal neonatal auditory brainstem responses (ABRs) and 4‐month arousal‐modulated attention visual preference to later autism spectrum disorder (ASD) behaviors in neonatal intensive care unit (NICU) graduates. A longitudinal study design was used to compare NICU graduates with normal ABRs (n = 28) to those with initially abnormal ABRs (n = 46) that later resolved. At 4 months postterm age, visual preference (measured after feeding) for a random check pattern flashing at 1, 3, or 8 Hz and gestational age (GA) served as additional predictors. Outcome measures were PDD Behavior Inventory (PDDBI) scores at 3.4 years (standard deviation = 1.2), and developmental quotients (DQ) obtained around the same age with the Griffiths Mental Development Scales (GMDS). Preferences for higher rates of stimulation at 4 months were highly correlated with PDDBI scores (all P‐values < 0.01) and the GMDS Hearing and Speech DQ, but only in those with initially abnormal ABRs. Effects were strongest for a PDDBI social competence measure most associated with a diagnosis of autism. For those with abnormal ABRs, increases in preference for higher rates of stimulation as infants were linked to nonlinear increases in severity of ASD at 3 years and to an ASD diagnosis. Abnormal ABRs were associated with later reports of repetitive and ritualistic behaviors irrespective of 4‐month preference for stimulation. The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort. Autism Res 2012, ●●:●●–●●. © 2012 International Society for Autism Research, Wiley Periodicals, Inc.
Synthesis and Biological Evaluation of Gramicidin S‐Inspired Cyclic Mixed α/β‐Peptides
Authors: van der Knaap Matthijs , Basalan Fatih , van de Mei Henny C. , Busscher Henk J. , van der Marel Gijsbert A. , Overkleeft Herman S. , Overhand Mark
Published: November 2012

Via a Mannich reaction involving a dibenzyliminium species and the titanium enolates of Evans' chiral acylated oxazolidinones the β2‐amino acids (R)‐ and (S)‐Fmoc‐β2homovaline and (R)‐Fmoc‐β2homoleucine are synthesized. These building blocks were used, in combination with commercially available α‐ and β3‐amino acids, for the synthesis of the cyclo‐(αβ3αβ2α)2 peptide 2 and the cyclo‐(αβ2αβ3α)2 peptides 3–5. The peptides 2–5 were screened for their ability to inhibit a small panel of Gram‐negative and Gram‐positive bacterial strains.
Total Synthesis of the Peptaibols Hypomurocin A3 and Hypomurocin A5, and Their Conformation Analysis
Authors: Pradeille Nicolas , Tzouros Manuel , Möhle Kerstin , Linden Anthony , Heimgartner Heinz
Published: November 2012

The total syntheses of hypomurocin A3 and hypomuricin A5 (HM A3 and HM A5, resp.) in solution phase are described. These syntheses have been successfully achieved by applying the ‘azirine/oxazolone method’ to introduce the two Aib‐Pro units into the backbone of these undecapeptaibols in one step with methyl 2,2‐dimethyl‐2H‐azirine‐3‐prolinate as the ‘Aib‐Pro synthon’. The coupling of Z‐protected (Z=(benzyloxy)carbonyl) amino acids or peptide acids with amino acid tert‐butyl esters and of peptide segments was carried out according to the TBTU (=O‐(benzotriazol‐1‐yl)‐N,N,N′,N′‐tetramethyluronium tetrafluoroborate) and HOBt (=1‐hydroxybenzotriazole) protocol. Purification by reversed‐phase HPLC gave the peptides in pure form. The products were characterized by optical rotation, NMR and IR spectroscopy, mass spectrometry, and elemental analysis. The crystal structures of HM A3 and of an octapeptide fragment of HM A5 could be obtained. An NMR analysis was also carried out with HM A3 and HM A5 to determine their conformations in solution. A global structural comparison between the three sequences of HM A1, HM A3, and HM A5 was performed, as well as the HPLC correlation of the natural HM A family and the synthetic samples.
Analogs of the Antituberculous Agent Pyrazinamide Are Competitive Inhibitors of NADPH Binding to M. tuberculosis Fatty Acid Synthase I
Authors: Sayahi Halimah , Pugliese Kaitlin M. , Zimhony Oren , Jacobs William R. , Shekhtman Alexander , Welch John T.
Published: November 2012

Analogs of pyrazinamide (=pyrazine‐2‐carboxamide; PZA), an essential component of short‐course antituberculous chemotherapy, such as 5‐chloropyrazinamide (5‐Cl‐PZA) act as competitive inhibitors of NADPH binding to purified mycobacterial fatty acid synthase I (FAS I) as shown by Saturation Transfer Difference (STD) NMR studies. In addition, pyrazinoic acid esters (POE) and 5‐Cl‐POE reversibly bind to FAS I with the relatively greater affinity of longer‐chain esters for FAS I, clear from the STD amplification factors. The competitive binding of PZA and 5‐Cl‐PZA clearly illustrates that both agents bind FAS. In contrast to PZA, at low NADPH concentrations 5‐Cl‐PZA is a cooperative inhibitor of NADPH binding.
Bacterial β‐Aminopeptidases: Structural Insights and Applications for Biocatalysis
Authors: Heck Tobias , Geueke Birgit , Kohler Hans‐Peter E.
Published: November 2012

β‐Aminopeptidases comprise a class of enzymes with functional and structural similarities. All members of the β‐aminopeptidases described to date were isolated from bacterial sources. Uniquely, they catalyze the hydrolysis of β3‐ and/or β2‐amino acid residues from amides and peptides that are otherwise considered proteolytically stable. Due to this unusual reactivity with β‐peptide substrates, β‐aminopeptidases have potential to be used as biocatalysts for β‐peptide synthesis and for the resolution of enantiomerically pure β‐amino acids from racemic substrate mixtures. β‐Aminopeptidases are formed from an inactive precursor by posttranslational autoproteolytic cleavage, exposing the catalytic nucleophile at the N‐terminus of the newly formed β‐polypeptide chain. Such an activation step is a characteristic trait of enzymes of the N‐terminal nucleophile (Ntn) hydrolase superfamily. However, classical Ntn hydrolases and β‐aminopeptidases differ by the fold of their catalytic cores and are hence likely to originate from distinct evolutionary ancestors. In this contribution, we review the existing literature on β‐aminopeptidases, including biochemical and functional studies, as well as structural investigations that recently allowed insights into the catalytic mechanisms of precursor processing and β‐peptide conversion.
Preparation of Recoverable Pd Catalysts for Carbonylative Cross‐Coupling and Hydrogenation Reactions
Authors: Niu Jian‐Rui , Huo Xing , Zhang Feng‐Wei , Wang Hai‐Bo , Zhao Ping , Hu Wu‐Quan , Ma Jiantai , Li Rong
Published: November 2012

We report on the synthesis, characterization and catalytic performance of new, supported PdII and Pd0 catalysts. The catalysts are characterized by TEM, XRD, FTIR, X‐ray photoelectron spectroscopy, and vibrating sample magnetometry. The catalysts are found to be active in both forms, PdII and Pd0, for the carbonylative cross‐coupling reaction of aryl iodides with arylboronic acids, and for the hydrogenation of aromatic nitro‐ and unsaturated compounds. The newly developed catalysts are prepared by a synthetic strategy that is similar to the one used for other supported catalysts but are easier to recover—they can be recycled by magnetic separation from liquid phase reactions—and can be used for at least 5 consecutive trials without any decrease in activity.
Palladium‐Catalysed Direct Polyarylation of Pyrrole Derivatives
Authors: Zhao Liqin , Bruneau Christian , Doucet Henri
Published: November 2012

The palladium‐catalysed direct polyarylation of 1‐methylpyrrole and 1‐phenylpyrrole was studied. As the C2 and C5 positions of pyrroles are more reactive for CH bond functionalisation than the C3 and C4 positions, the formation of 2,5‐diarylpyrroles was found to proceed selectively in the presence of 3 equiv. of a variety of aryl bromides. The sequential C2 arylation followed by C5 arylation to prepare non‐symmetrically substituted 2,5‐diarylpyrroles was also studied. For the synthesis of such pyrroles, higher yields were obtained for the couplings with electron‐deficient aryl bromides. The tetraarylation of 1‐methylpyrrole was also achieved. From 4 equiv. of 3,5‐bis(trifluoromethyl)bromobenzene, the 2,3,4,5‐tetraarylated pyrrole was obtained in good yield.
ChemInform Abstract: Crystal Structure Study of New Lanthanide Silicates with Silico‐Carnotite Structure.
Authors: Piccinelli F. , Lausi A. , Speghini A. , Betinelli M.
Published: November 2012

The new compounds Ca3Ln2Si3O12 (Ln: La, Nd, Sm, Eu, Gd, Tb, Er, Lu) are synthesized by solid state reaction of CaCO3, SiO2, and Ln2O3 (1450 °C, 9 h) and their crystal structures are determined by powder XRD.
ChemInform Abstract: Neutron and X‐Ray Diffraction Studies on the High Temperature Phase of Mn3(VO4)2, the New Isostructural Compound NaMn4(VO4)3 and Their Mixed Crystals NaxMn4.5‐x/2(VO4)3 (0 ≤ x ≤ 1).
Authors: Clemens Oliver , Haberkorn Robert , Springborg Michael , Beck Horst Philipp
Published: November 2012

NaMn4(VO4)3 and NaxMn4.5‐x/2(VO4)3 (0 ≤ x ≤ 1) are synthesized by solid state reaction of stoichiometric mixtures of Na2CO3, MnO, and V2O5 (Pt boat, argon stream, 900 °C, 20 h).
ChemInform Abstract: Crystal Growth and Magnetic Properties of Ln‐Mn‐Al (Ln: Gd, Yb) Compounds of the CaCr2Al10 and ThMn12 Structure Types.
Authors: Fulfer Bradford W. , Haldolaarachchige Neel , Young David P. , Chan Julia Y.
Published: November 2012

Single crystals of GdMn3.76Al8.24 (I), YbMn2.55Al9.45 (II), YbMn2.92Al9.08 (III), GdMn2.21Al9.79 (IV), YbMn2.06Al9.94 (V), YbMn2.10Al9.90 (VI), YbMn2.17Al9.9.83 (VII), and YbMn2.27Al9.74 (VIII) are prepared from the elements (alumina crucibles, 950—1200 °C, 12—72 h) and characterized by single crystal XRD, magnetization, and electrical transport measurements.
ChemInform Abstract: Additive‐Assisted Synthesis of Boride, Carbide, and Nitride Micro/Nanocrystals.
Authors: Chen Bo , Yang Lishan , Heng Hua , Chen Jingzhong , Zhang Linfei , Xu Liqiang , Qian Yitai , Yang Jian
Published: November 2012

A series of boride (TiB2, ZrB2, NbB2, CeB6, PrB6, SmB6, EuB6, LaB6), carbide (SiC, TiC, NbC, WC), and nitride (TiN, BN, AlN, MgSiN2, VN) micro/nanocrystals are prepared from the corresponding metal oxides and amorphous boron/active carbon/NaN3 in the presence of metallic Na and elemental S (autoclave, 150 °C, 2 h).
ChemInform Abstract: Segregation of Cd2 Pairs in CaCu9Cd2 and EuCu9Cd2.
Authors: Tappe Frank , Schwickert Christian , Poettgen Rainer
Published: November 2012

CaCu9Cd2 and EuCu9.14Cd1.86 are synthesized by solid state reaction of stoichiometric mixtures of the elements (argon, Ta tubes, high frequency furnace; 1.
ChemInform Abstract: Expanded Substrate Scope and Catalyst Optimization for the Catalytic Kinetic Resolution of N‐Heterocycles.
Authors: Hsieh Sheng‐Ying , Binanzer Michael , Kreituss Imants , Bode Jeffrey W.
Published: November 2012

Scope, reactivity, and selectivity of the chiral hydroxamic acid‐catalyzed kinetic resolution of chiral amines are improved compared to the original conditions by a improved catalyst structure and a more environmentally friendly reaction protocol.
ChemInform Abstract: Nickel‐Catalyzed Diastereoselective Alkyl—Alkyl Kumada Coupling Reactions.
Authors: Perez Garcia Pablo M. , Di Franco Thomas , Orsino Alessio , Ren Peng , Hu Xile
Published: November 2012

1,4‐Cyclohexyl halides (Br, I) undergo a coupling reaction with alkyl or aryl Grignard reagents in the presence of nickel pincer complex TAN to give trans‐1,4‐disubstituted cyclohexanes as major products.
ChemInform Abstract: Reaction of 2‐(Trifluoromethyl)chromones with Pyridoxal: Formation of 1‐Benzopyranooxepino‐ and 1‐Benzopyranopyranopyridines.
Authors: Sosnovskikh Vyacheslav Ya. , Korotaev Vladislav Yu. , Barkov Alexey Yu. , Sokovnina Anna A. , Kodess Mikhail I.
Published: November 2012

The reaction is conducted under environmentally benign conditions.
ChemInform Abstract: NH4OAc Promoted Cyclocondensation of 3‐(o‐Allylphenyl)pentane‐1,5‐diones: Synthesis of Tetracyclic Benzofused 1‐Azahomoisotwistanes.
Authors: Chang Meng‐Yang , Wu Ming‐Hao , Tai Hang‐Yi
Published: November 2012

The reaction allows a new and facile access to tetracyclic ring systems of type (IV).
ChemInform Abstract: Gold‐Catalyzed Cycloisomerization of 1,7‐Diyne Benzoates to Indeno[1,2‐c]azepines and Azabicyclo[4.2.0]octa‐1(8),5‐dines.
Authors: Rao Weidong , Koh Ming Joo , Kothandaraman Prasath , Chan Philip Wai Hong
Published: November 2012

The gold‐catalyzed cycloisomerization of 1,7‐diyne benzoates is strongly influenced by steric effects around the propargylamine moiety.
ChemInform Abstract: Synthesis of Enantiopure Tertiary Skipped Diynes via One‐Pot Desymmetrizing TMS‐Cleavage.
Authors: Nechab Malek , Vanthuyne Nicolas
Published: November 2012

Addition of the acetylide (II) to tosylated α‐amino esters allows the unexpected formation of desymmetrized diynes such as (III), (VI), and (IX) via stereoselective cleavage of one Tms group.
ChemInform Abstract: A C—H Borylation Approach to Suzuki—Miyaura Coupling of Typically Unstable 2—Heteroaryl and Polyfluorophenyl Boronates.
Authors: Robbins Daniel W. , Hartwig John F.
Published: November 2012

Biaryls and heterobiaryls are prepared from heteroarenes/fluorobenzenes in two steps involving the iridium‐catalyzed C—H borylation with bis(pinacolato)diboron (or the corresponding monomer) to give intermediate pinacol boronate esters which undergo the coupling with aryl bromides or chlorides.The pinacol boronate esters act as surrogates for their corresponding unstable boronic acids.
ChemInform Abstract: Iron(II) Catalyzed Dehydrative Etherification of Alcohols: A Convenient Route to Ferrocenylmethanol‐Ethers.
Authors: Busetto Luigi , Mazzoni Rita , Salmi Mauro , Zacchini Stefano , Zanotti Valerio
Published: November 2012

The iron complex [Fe(CO)2(Cp)]OTf is found to be an excellent catalyst in the dehydrative etherification of ferrocenylmethol (I) with alcohols, in particular with propargyl alcohol.
ChemInform Abstract: A Mild and Versatile Method for the Synthesis of Alkyl Ethers from Methoxymethyl Ethers and Application to the Preparation of Sterically Crowded Ethers.
Authors: Minamitsuji Yutaka , Kawaguchi Atsuhisa , Kubo Ozora , Ueyama Yoshifumi , Maegawa Tomohiro , Fujioka Hiromichi
Published: November 2012

Methoxymethyl or 1‐methoxyethyl ether derivatives are transformed by a one‐pot two‐step sequence into the corresponding alkyl ether derivatives via pyridinium salt intermediates, which are added to organocuprates generated in situ from CuI and alkyl/aryl Grignard reagents.
ChemInform Abstract: Rearrangement of N‐tert‐Butanesulfinyl α‐Halo Imines with Alkoxides to N‐tert‐Butanesulfinyl 2‐Amino Acetals as Precursors of N‐Protected and N‐Unprotected α‐Amino Carbonyl Compounds.
Authors: Colpaert Filip , Mangelinckx Sven , Denolf Bram , De Kimpe Norbert
Published: November 2012

This methods can be applied to prepare biologically active (S)‐cathinone (X).
ChemInform Abstract: Rhodium/Chiral Diene‐Catalyzed Asymmetric Methylation of N‐Sulfonylarylimines with Trimethylboroxine.
Authors: Nishimura Takahiro , Ashouri Akram , Ebe Yusuke , Maeda Yuko , Hayashi Tamio
Published: November 2012

The present new method is applicable to produce various chiral arylethylamines (III) in high yields and high enantioselectivities tolerating several functional groups even at ortho‐position.
ChemInform Abstract: Synthesis of Unsymmetrical Biaryl Ethers Through Nickel‐Promoted Coupling of Polyfluoroarenes with Arylboronic Acids and Oxygen.
Authors: Zhang Jian , Wu Jingjing , Xiong Yang , Cao Song
Published: November 2012

Polyfluoro‐substituted unsymmetrical biaryl ethers (III) are synthesized via a novel Ni‐catalyzed cross‐coupling reaction of polyfluoroarenes (I) with arylboronic acids (II) and oxygen.
ChemInform Abstract: Porous Metalloporphyrinic Frameworks Constructed from Metal 5,10,15,20‐Tetrakis(3,5‐biscarboxylphenyl)porphyrin for Highly Efficient and Selective Catalytic Oxidation of Alkylbenzenes.
Authors: Yang Xiu‐Li , Xie Ming‐Hua , Zhou Chao , He Yabing , Chen Banglin , O'Keeffe Michael , Wu Chuan‐De
Published: November 2012

The porous metalloporphyrinic framework shown in the scheme efficiently catalyses the selective oxidation of ethylbenzene to acetophenone in quantitative yield and with a turnover number of 8076 after 48 hours.
ChemInform Abstract: Transition‐Metal‐Free C‐Arylation at Room Temperature by Arynes.
Authors: Dhokale Ranjeet A. , Thakare Pramod R. , Mhaske Santosh B.
Published: November 2012

Treatment of the protected malonamide (I) with excess arynes allows facile and selective access to monoarylated products like (III).
ChemInform Abstract: Hydrosilane and Bismuth‐Accelerated Palladium Catalyzed Aerobic Oxidative Esterification of Benzylic Alcohols with Air.
Authors: Bai Xing‐Feng , Ye Fei , Zheng Long‐Sheng , Lai Guo‐Qiao , Xia Chun‐Gu , Xu Li‐Wen
Published: November 2012

Hydrosilane serves as an activator of Pd‐catalyst with bismuth, thus leading to a novel ligand‐free Pd catalyst system for facile oxidative esterification of a variety of benzylic alcohols (I), (IV), and (VI).
ChemInform Abstract: A Green, Mild and Efficient One‐Pot Method for the Synthesis of Sulfonamides from Thiols and Disulfides in Water.
Authors: Massah Ahmad Reza , Sayadi Safura , Ebrahimi Sara
Published: November 2012

The method employs trichloroisocyanuric acid for the oxidative chlorination of disulfide (I) to produce the corresponding sulfonyl chloride in the first step.
ChemInform Abstract: Alkyne Hydrothiolation Catalyzed by a Dichlorobis(aminophosphine) Complex of Palladium: Selective Formation of cis‐Configured Vinyl Thioethers.
Authors: Gerber Roman , Frech Christian M.
Published: November 2012

Hydrothiolation of terminal aromatic and symmetrical internal aromatic alkynes furnishes selectively the Z‐configured anti‐Markovnikov‐type addition products.
ChemInform Abstract: Cobalt‐Catalyzed ortho‐Arylation of Aromatic Imines with Aryl Chlorides.
Authors: Gao Ke , Lee Pin‐Sheng , Long Chong , Yoshikai Naohiko
Published: November 2012

The Co(II)/imidazolium catalyst in combination with neopentylmagnesium bromide allows arylation at room temperature.
ChemInform Abstract: Chemoselectivity of 2‐Arylmethyleneaminoisoindolin‐1,3‐diones Toward Arenes under Friedel—Crafts Conditions: An Efficient Synthesis of Benzophenones Integrated with 2‐Substituted Hydrazone Moieties.
Authors: Derbala Hamed A.
Published: November 2012

Reaction of title arylideneaminoisoindolinones (I) with arenes in the system AlCl3—DMF provides access towards hydrazone‐bearing benzophenones (III) as novel potentially bioactive compounds.
ChemInform Abstract: Regioselective Monobromination of (E)‐1‐(2′‐Hydroxy‐4′,6′‐dimethoxyphenyl)‐3‐aryl‐2‐propen‐1‐ones Using Bromodimethylsulfonium Bromide and Synthesis of 8‐Bromoflavones and 7‐Bromoaurones.
Authors: Khan Abu T. , Choudhury Abhik , Ali Shahzad , Khan Md. Musawwer
Published: November 2012

A facile method is presented for the regioselective ring monobromination of arylpropenones (I).
ChemInform Abstract: Design, Synthesis and Anticancer Activity of Nitric Oxide Donating/Chalcone Hybrids.
Authors: Mourad Mai A. E. , Abdel‐Aziz Mohamed , Abuo‐Rahma Gamal El‐Din A. A. , Farag Hassan H.
Published: November 2012

Several nitric oxide (NO) releasing chalcone derivatives (I) are prepared by coupling amino chalcones with different NO‐donating moieties including nitrate esters, furoxans, and oximes.
ChemInform Abstract: Merging Tribenzotriquinacene with Hexa‐peri‐hexabenzocoronene: A Cycloheptatriene Unit Generated by Scholl Reaction.
Authors: Mughal Ehsan Ullah , Kuck Dietmar
Published: November 2012

The single‐wing extension of the bowl‐shaped tribenzotriquinacene framework (TBTQ) with polycondensed aromatic hydrocarbon units is reported.
ChemInform Abstract: Asymmetric Allylic Alkylation of Isatin‐Derived Morita—Baylis—Hillman Carbonates with Nitroalkanes.
Authors: Chen Guo‐Ying , Zhong Fangrui , Lu Yixin
Published: November 2012

The chiral alcohol efficiently promotes the reaction of carbonates of type (I) with nitroalkanes giving biologically important 3,3‐disubstituted oxindoles are obtained with excellent enantioselectivity and moderate to good diastereoselectivity.
ChemInform Abstract: Efficient Assembly of 3‐Substituted Oxindole‐Based Isoxazolines Leading to the Synthesis of (.+‐.)‐Flustraminol‐B and Related Natural Product Building Blocks.
Authors: Singh Anand , Roth Gregory P.
Published: November 2012

1,3‐Dipolar cycloaddition of nitrile oxides with oxoindole derivatives (I) and (IX) provides the title compounds.
ChemInform Abstract: DABCO‐Mediated One‐Pot Sequential Transformation: Convenient Access to Fluorinated 1H‐Pyrazol‐5(4H)‐ones.
Authors: Wu Jun‐Wei , Li Feng , Zheng Yan , Nie Jing
Published: November 2012

A one‐pot sequential allylic alkylation of pyrazolones with Morita—Baylis—Hillman carbonates and electrophilic fluorination allows the synthesis of pharmaceutically interesting title compounds (III) and (VIII).
ChemInform Abstract: Phosphazenes. Part 1. Reactions with Electron‐Deficient Alkenes.
Authors: Yangirov T. A. , Zubairova G. R. , Sultanova R. M. , Biglova R. Z. , Dokichev V. A. , Tomilov Yu. V.
Published: November 2012

Phosphazenes (I) react with electron‐deficient alkenes in a selective fashion furnishing 4,5‐dihydropyrazoles.
ChemInform Abstract: Synthesis of Trisubstituted Isoxazoles via in situ Trapping Strategy from α‐Nitro Carbonyl Compounds and Methyl Ketones or Terminal Aryl Alkenes.
Authors: Yang Yan , Gao Meng , Deng Cong , Zhang Dong‐Xue , Wu Liu‐Ming , Shu Wen‐Ming , Wu An‐Xin
Published: November 2012

A novel route for the synthesis of isoxazoles starts from easily available α‐nitroketones and methylketones or terminal aryl alkenes.
ChemInform Abstract: Benzothiazolium‐Functionalized Tetraphenylethene: An AIE Luminogen with Tunable Solid‐State Emission.
Authors: Tang Ben Zhong , et al. et al.
Published: November 2012

The luminescence properties of the new title compound (I) are investigated in THF and THF/H2O‐mixtures.
ChemInform Abstract: Synthesis of Some Tetrazole‐Fused Pyrido[2,3‐c]coumarin Derivatives from a One‐Pot Three‐Component Reaction via Intramolecular 1,3‐Dipolar Cycloaddition Reaction of Azide to Nitriles.
Authors: Borah Pallabi , Naidu P. Seetham , Bhuyan Pulak J.
Published: November 2012

A simple protocol allows the synthesis of various biologically interesting title systems.
ChemInform Abstract: General Non‐catalytic Approach to Spiroacenaphthylene Heterocycles: Multicomponent Assembling of Acenaphthenequinone, Cyclic CH‐Acids and Malononitrile.
Authors: Elinson Michail N. , Ilovaisky Alexey I. , Merkulova Valentina M. , Belyakov Pavel A. , Barba Fructuoso , Batanero Belen
Published: November 2012

This new, convenient, and facile procedure represents the most effective and ′green′ approach to the reliable design of the title compounds.
ChemInform Abstract: Organocatalytic One‐Pot Asymmetric Synthesis of 4H,5H‐Pyrano[2,3‐c]pyrazoles.
Authors: Enders Dieter , Grossmann Andre , Gieraths Bianca , Duezdemir Muharrem , Merkens Carina
Published: November 2012

The title compounds are obtained from α,β‐unsaturated aldehydes, aromatic phosphorus ylides, and pyrazolones in the presence of prolinol‐derived catalyst PRO via an asymmetric Michael/Wittig/oxa‐Michael reaction sequence.
ChemInform Abstract: A Facile and Efficient Synthesis of 2‐Amino‐3‐cyano‐4H‐chromenes and Tetrahydrobenzo[b]pyrans Using 2,2,2‐Trifluoroethanol as a Metal‐Free and Reusable Medium.
Authors: Khaksar Samad , Rouhollahpour Ahmad , Talesh Saeed Mohammadzadeh
Published: November 2012

Compounds (IV) are purified by recrystallization.
ChemInform Abstract: Studies on Reactive Pyridylketones Formed by Weinreb Transformations.
Authors: Stockmann Vegar , Kaspersen Svein Jacob , Nicolaisen Alexander , Fiksdahl Anne
Published: November 2012

A method for the preparation of reactive pure vinylpyridylketones and activated vinylketones and their use in further reactions such as cycloadditions are described.
ChemInform Abstract: Synthesis of Pyridine‐2,6‐bis((E)‐2‐benzylidene‐3‐oxo‐propanenitrile) and Its Behavior Towards Nitrogen Binucleophiles.
Authors: Ali Korany A.
Published: November 2012

Condensation of the bis(β‐keto nitrile) (I) with aromatic aldehydes (II) yields the Knoevenagel products (III).
ChemInform Abstract: Synthesis and Evaluation of 4‐Aryl‐2(1H)‐quinolinones as Potent Amyloid β Fibrillogenesis Inhibitors.
Authors: Shimokawa Yoko , Nakakoshi Masamichi , Saito Setsu , Suzuki Hideharu , Yokoyama Yuusaku , Ishigami Akihito , Nishioka Hideo , Tsubuki Masayoshi
Published: November 2012

Arylquinolinones (IV) are prepared by Knorr cyclization of benzoylacetoanilides (III).
ChemInform Abstract: Palladium‐Catalyzed Construction of Poly‐Substituted Indolizinones.
Authors: Cho Hanyang , Kim Ikyon
Published: November 2012

A full and detailed account on previously published studies is presented.
ChemInform Abstract: Facile Synthesis of Imidazole Fused Fluoroquinolones.
Authors: Reddy G. Venkat , Shekhar A. Chandra , Kumar A. Ravi , Sathaiah G. , Narsaiah B. , Rao P. Shanthan
Published: November 2012

None of the prepared compounds shows promising antibacterial activity as compared to ciprofloxacin.
ChemInform Abstract: Iridium‐Catalyzed [2 + 2 + 2] Cycloaddition of α,ω‐Diynes with Nitriles.
Authors: Onodera Gen , Shimizu Yoshihisa , Kimura Jun‐na , Kobayashi Junya , Ebihara Yukiko , Kondo Kei , Sakata Ken , Takeuchi Ryo
Published: November 2012

A simple catalyst system, obtained by mixing of Ir2Cl2(cod)2 with diphosphine ligands in situ, allows for efficient preparation of pyridine derivatives from nitriles and alkynes.
ChemInform Abstract: Design, Synthesis and Biological Activity Evaluation of 2‐Mercapto‐4(3H)‐quinazolinone Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B.
Authors: Li Hui , Wang Jin‐Ping , Yang Fan , Liu Ting , Qiu Wen‐Wei , Li Jing‐Ya , Li Jia , Tang Jie
Published: November 2012

The title derivatives are obtained by reaction of aminobenzoic acid with formamide/isothiocyanate or by reaction of 4‐substituted aminobenzoic acid derivatives (I) with phenyl isothiocyanate (II), followed by further derivatization.
ChemInform Abstract: Lewis Acid Catalyzed Synthesis of 1‐Aryl‐1,2‐dihydro‐naphtho[1,2‐e][1,3]oxazin‐3‐ones under Solvent Free Conditions: A Mechanistic Approach.
Authors: Sharma Mukul , Manohar Sunny , Rawat Diwan S.
Published: November 2012

The title compounds (IV) are obtained in a Lewis acid catalyzed highly efficient one‐pot three‐component condensation of β‐naphthol (I), urea (II), and various aromatic aldehydes (III) at high temperature.
ChemInform Abstract: Highly Efficient Asymmetric Synthesis of Enantiopure Dihydro‐1,2‐oxazines: Dual‐Organocatalyst‐Promoted Asymmetric Cascade Reaction.
Authors: Lin Hua , Tan Yu , Sun Xing‐Wen , Lin Guo‐Qiang
Published: November 2012

The oxazine products can be converted into optically active 1,4‐amino alcohols.
ChemInform Abstract: A One‐Pot—Three‐Step Route to Triazolotriazepinoindazolones from Oxazolino‐2H‐indazoles.
Authors: Conrad Wayne E. , Rodriguez Kevin X. , Nguyen Huy H. , Fettinger James C. , Haddadin Makhluf J. , Kurth Mark J.
Published: November 2012

Sequential treatment of oxazolinoindazoles with propargyl bromides and NaN3 allows an efficient access to a number of target compounds.
ChemInform Abstract: Wittig Homologation of 2‐(Chloromethyl)‐2H‐chromen‐2‐ol Derivatives: A New Facile Synthesis of Substituted 2,3‐Dihydrobenzoxepine‐4‐carboxylates.
Authors: Raju Bhimapaka China , Saidachary Gannerla , Kumar Jaladi Ashok
Published: November 2012

The title compounds are synthesized by Wittig reaction of chromenol derivatives (I) and (VIII) with commercially available phosphoranes (II).
ChemInform Abstract: Oxidative Condensations to Form Benzimidazole‐Substituted Potassium Organotrifluoroborates.
Authors: Molander Gary A. , Ajayi Kehinde
Published: November 2012

The method is applied to the synthesis of 2‐biaryl‐substituted benzimidazoles by combination of the oxidative condensation step with the Suzuki—Miyaura cross‐coupling reaction.
ChemInform Abstract: Green Synthesis and Bioactivity of 2‐Amino‐4H‐chromen‐4‐yl‐phosphonates.
Authors: Rajasekhar Mekala , Rao Kunda Uma Maheswara , Sundar Chereddy Syama , Reddy Nemallapudi Bakthavatchala , Nayak Sandip Kumar , Reddy Cirandur Suresh
Published: November 2012

A new, simple and efficient green synthesis of the title chromenylphosphonates (IV) (12 examples) using a multicomponent reaction is developed.
ChemInform Abstract: An Efficient Synthesis of Enol Phosphates via Organic Base‐Promoted Addition of Phosphites to 4‐Oxo‐enoates.
Authors: Zhu Xiao‐Yu , Chen Jia‐Rong , Lu Liang‐Qiu , Xiao Wen‐Jing
Published: November 2012

A practical, mild, and convenient protocol for the synthesis of the title compounds is described by using a simple and cheap catalyst.
ChemInform Abstract: Synthesis of a Stable 1,2‐Bis(ferrocenyl)diphosphene.
Authors: Sasamori Takahiro , Sakagami Michiyasu , Niwa Masatoshi , Sakai Heisuke , Furukawa Yukio , Tokitoh Norihiro
Published: November 2012

The synthesis and characterization of the title compound (III), wherein a P=P π‐bond connects two bulky ferrocenyl units is reported.
ChemInform Abstract: Synthesis and in vitro Antitumor Activity of 1,3,4‐Oxadiazole Derivatives Based on Benzisoselenazolone.
Authors: Luo Zhen‐Hua , He Shuang‐Yan , Chen Bao‐Quan , Shi Yan‐Ping , Liu Yu‐Ming , Li Cai‐Wen , Wang Qiu‐Sheng
Published: November 2012

The title compounds (V) are screened for their in vitro antiproliferative activities against three different human cancer cell lines.
ChemInform Abstract: A New Synthetic Strategy for Catechin‐Class Polyphenols: Concise Synthesis of (‐)‐Epicatechin and Its 3‐O‐Gallate.
Authors: Stadlbauer Sven , Ohmori Ken , Hattori Fumihiko , Suzuki Keisuke
Published: November 2012

Key steps of the described sequence are the assembly of lithiated fluorobenzene which functions as A‐ring surrogate, and the enantiopure epoxide (II) followed by pyran annulation.
ChemInform Abstract: Self‐Organization of Extraframework Cations in Zeolites
Authors: Pidko Evgeny A. , Hensen Emiel J. M. , Van Santen Rutger A.
Published: November 2012

Review: 56 refs.
ChemInform Abstract: Origin of Hysteresis in La0.67Ca0.33MnO3
Authors: Morrison K. , Berenov A. , Cohen L. F.
Published: November 2012

Review: 39 refs.
ChemInform Abstract: Cold Neutron Scattering Studies of Frustrated Pyrochlore Antiferromagnets
Authors: Gardner J. S. , Rule K. C. , Ruff J. P. C. , Clancy J. P. , Gaulin B. D.
Published: November 2012

Review: 28 refs.
ChemInform Abstract: Organometallic Complexes of Transition Metals in Luminescent Cell Imaging Applications
Authors: Thorp‐Greenwood Flora L. , Balasingham Rebeca G. , Coogan Michael P.
Published: November 2012

Review: 64 refs.
ChemInform Abstract: Self‐Assembly Driven by an Aromatic Primary Amide Motif
Authors: Seo Myungeun , Park Jeyoung , Kim Sang Youl
Published: November 2012

Review: 59 refs.
ChemInform Abstract: Gold Nanoparticle‐Catalyzed Formation of Nitrogen‐Containing Compounds — From Mechanistic Understanding to Synthetic Exploitation.
Authors: Mielby Jerrik , Kegnaes Soeren , Fristrup Peter
Published: November 2012

Review: 69 refs.
ChemInform Abstract: Direct α‐Functionalization of Saturated Cyclic Amines
Authors: Mitchell Emily A. , Peschiulli Aldo , Lefevre Nicolas , Meerpoel Lieven , Maes Bert U. W.
Published: November 2012

Review: 126 refs.
ChemInform Abstract: Recent Developments in the Synthesis and Application of Sultones
Authors: Mondal Shovan
Published: November 2012

Review: 134 refs.
ChemInform Abstract: Catalysis in Hydrogen‐Bridged Radical Cations
Authors: Jobst Karl J. , Trikoupis Moschoula A.
Published: November 2012

Review: 50 refs.
ChemInform Abstract: Self‐Assembly of Superparamagnetic Nanoparticles
Authors: Bao Ningzhong , Gupta Arunava
Published: November 2012

Review: 65 refs.
ChemInform Abstract: Graphene‐Based Catalysts
Authors: Huang Cancan , Li Chun , Shi Gaoquan
Published: November 2012

Review: 285 refs.
ChemInform Abstract: Radical Azidation Reactions and Their Application in the Synthesis of Alkaloids
Authors: Lapointe Guillaume , Kapat Ajoy , Weidner Karin , Renaud Philippe
Published: November 2012

Review: 49 refs.
ChemInform Abstract: Stereoselective Biotransformations as an Effective Tool for the Synthesis of Chiral Compounds with P—C Bond: Scope and Limitations of the Methods
Authors: Zymanczyk‐Duda Ewa , Klimek‐Ochab Magdalena
Published: November 2012

Review: 109 refs.
ChemInform Abstract: Marine Natural Products
Authors: Hill Robert A.
Published: November 2012

Review: 107 refs.
ChemInform Abstract: Protein Engineering of Stereoselective Baeyer—Villiger Monooxygenases
Authors: Zhang Zhi‐Gang , Parra Loreto P. , Reetz Manfred T.
Published: November 2012

Review: ca. 100 refs.
ChemInform Abstract: Merging Organocatalysis and Gold Catalysis — A Critical Evaluation of the Underlying Concepts
Authors: Loh Charles C. J. , Enders Dieter
Published: November 2012

Review: about 100 refs.
ChemInform Abstract: Soft X‐Ray Imaging and Spectromicroscopy: New Insights in Chemical State and Morphology of the Key Components in Operating Fuel‐Cells
Authors: Bozzini Benedetto , Abyaneh Majid Kazemian , Amati Matteo , Gianoncelli Alessandra , Gregoratti Luca , Kaulich Burkhard , Kiskinova Maya
Published: November 2012

Review: 74 refs.
ChemInform Abstract: Optical and Vibrational Spectroscopy and Density Functional Theory Modeling of Large PAHs
Authors: Elliott Anastasia B. S. , Gordon Keith C.
Published: November 2012

Review: 82 refs.
ChemInform Abstract: High Resolution Magic Angle Spinning NMR Applied to the Analysis of Organic Compounds Bound to Solid Supports
Authors: Espinosa Juan F.
Published: November 2012

Review: 157 refs.
ChemInform Abstract: Challenges in Numerical Simulations of Solid‐State NMR Experiments: Spin Exchange Pulse Sequences
Authors: Vosegaard Thomas
Published: November 2012

Review: 83 refs.
Iterative estimation of MRI sensitivity maps and image based on sense reconstruction method (isense)
Authors: Majumdar Angshul , Ward Rabab K.
Published: November 2012

SENSitivity Encoding (SENSE) is a parallel MR image reconstruction technique that yields optimal results when the sensitivity maps are accurately known. Unfortunately, in practical scenarios, obtaining accurate estimates of the sensitivity maps is not possible. In this work, we propose a technique that iteratively reconstructs the image and refines the sensitivity maps (from initial estimates). Our technique is named iSENSE (iterative SENSE). Our proposed technique exploits the sparsity of the MR image in some transform domains or the rank deficiency characteristic of the matrix representing the MRI image; the former leads to a compressed sensing‐based reconstruction method, whereas the latter leads to an image reconstruction method that minimizes the nuclear norm (NN) of the image matrix. The sensitivity maps are assumed to be rank‐deficient matrices, and thus the refinement of the sensitivity maps is achieved via the NN minimization. To evaluate the performance of the proposed method, we have carried out the experiments on real and one simulated datasets. We have compared our method with three state‐of‐the‐art image domain methods—SparSENSE (Sparse SENSE), NNSENSE (NN Regularized SENSE), and JSENSE (Joint SENSE reconstruction)—and one widely used frequency domain method—GRAPPA (Generalized Autocalibrating Partially Parallel Acquisition). Our method yields the best reconstruction results both in quantitative (normalized mean‐squared error) and qualitative (visual inspection of reconstructed and difference images) evaluation. © 2012 Wiley Periodicals, Inc. Concepts Magn Reson Part A 40A: 269–280, 2012.
Revealing the Subtle Interplay of Thermal and Quantum Fluctuation Effects on Contact Ion Pairing in Microsolvated HCl
Authors: Walewski Łukasz , Forbert Harald , Marx Dominik
Published: November 2012

The combined effect of thermal fluctuations and quantum mechanical motion on the HCl(H2O)4 cluster is studied at different temperatures. Two conformations of this cluster are investigated: the ringlike structure that involves an undissociated HCl molecule (UD) and the contact ion pair (CIP), which involves the dissociated acid, Cl−, and H3O+. The UD structure is affected by thermal and quantum fluctuations in a similar way. The hydrogen‐bond network is destabilized, and this results in ring expansion and proton orientational rearrangements, though the thermal excitation prevails over the quantum effects at high temperature, while the zero‐point motion dominates in the low‐temperature regime, as expected. In contrast, the thermal and quantum fluctuations exert competing effects on the CIP structure. At high temperature one of the hydrogen bonds accepted by Cl− breaks, and this results in undercoordination of the Cl site, which leads to proton transfer along the fluxional Cl−⋅⋅⋅H3O+ hydrogen bond and formation of molecular HCl. Thus, thermal fluctuations counteract acid dissociation and thus ion‐pair formation. At low temperature however, the decreasing thermal excitations facilitate recovery of the full hydrogen‐bond network, which pushes the proton away from the Cl site and thus leads to acid dissociation, which characterizes the equilibrium structure. On the other hand, quantum mechanical fluctuations, which destabilize the hydrogen bonds supporting the Cl− ion and pull the proton back towards the undissociated limit, become of overriding importance in the low‐temperature limit. As a result, the subtle balance between the two trends enables temperature‐dependent “low‐barrier hydrogen bonding” and establishes a centered hydrogen bond, H2O⋅⋅⋅H+⋅⋅⋅Cl−, at intermediate temperatures.
Cytologic findings of acute leukemia in bronchoalveolar lavage fluid
Authors: O'Leary Michelle , Cantley Richard L. , Kluskens Larry , Gattuso Paolo
Published: November 2012

Bronchoalveolar lavage (BAL) is often performed in patients with acute leukemia developed with respiratory failure or pulmonary infiltrates. Patients usually undergo BAL to rule out infection. Occasionally, however, leukemic infiltrate may be detected. We present a series of 11 cases in which the diagnosis of leukemia was made on the BAL material. We retrospectively reviewed all BAL samples from January 1, 2006 to December 31, 2008. There were a total of 1,130 cases, of which 139 showed malignant cytology, including 10 with leukemia. Sixteen samples were unsatisfactory and 904 were benign, of which 32 had identifiable microorganisms. In additional to the 10 leukemia cases identified, two more were reviewed after the search criteria. The 12 patients (seven men, five women) ranged from 22 to 75 years old. All patients had previously biopsy‐proven leukemia [two acute myelomonocytic leukemia, two acute promyelocytic leukemia, two acute myeloid leukemia (AML) with inv16, two therapy‐related AML, one acute monocytic leukemia, one chronic myeloid leukemia in blast face, one AML with maturation, one myelodysplastic syndrome with excess blasts, and one large granular leukemia]. Four had a prior diagnosis of myelodysplastic syndrome. The time from initial diagnosis of leukemia to BAL ranged from 1 to 233 days, with 8 of 10 occurring within 8 days of diagnosis. Symptoms that prompted BAL included shortness of breath/hypoxia (8), fever (3), chest pain (2), and cough (2). Chest X‐rays in all cases revealed opacities or consolidations mimicking an inflammatory process. Seven patients subsequently died, while three were alive, and, in remission, and two were lost to follow‐up. The presence of a leukemic infiltrate can mimic infection. BAL is a relatively safe and useful diagnostic tool in this setting for differentiating a leukemic infiltrate from an infection/inflammatory infiltrate. The prognosis of patients with lung involvement of acute leukemia is poor. Diagn. Cytopathol. 2013. © 2012 Wiley Periodicals, Inc.
Gas Adsorption Properties and Selectivity in CuII/Adeninato/Carboxylato Metal–Biomolecule Frameworks
Authors: Pérez‐Yáñez Sonia , Beobide Garikoitz , Castillo Oscar , Fischer Michael , Hoffmann Frank , Fröba Michael , Cepeda Javier , Luque Antonio
Published: November 2012

Herein we report the analysis of the porosity of a family of MBioFs with formula [Cu2(μ3‐ade)2(μ‐OOCCH3)2]n (compound 1), [Cu2(μ3‐ade)2(μ‐OOCCH2CH3)2]n (compound 2) and [Cu2(μ3‐ade)2(μ‐OOC(CH2)2CH3)2]n (compound 3) [ade = adeninato], by means of the measurements of N2 (77 K), CO2 (273 K) and H2 (77 K) experimental adsorption isotherms. The experimental results for each adsorptive species show that the uptake capacity decreases on increasing the length of the aliphatic chain of the carboxylato ligand. Although, in general, all compounds show a moderate experimental uptake capacity, the amount of CO2 adsorbed in compound 1 exceeds the values reported for many other well‐known MOFs, which is related to the presence of the Watson–Crick face in the pore wall. The experimental data of all compounds is discussed on the basis of simulated isotherms computed from grand canonical Monte Carlo (GCMC) calculations. To assess the suitability of pores decorated by the Watson–Crick faces for the selective capture of CO2 and CO, the selectivity towards CO2/H2 and CO/H2 gas mixtures was analysed by computing the Henry constants and the binary adsorption isotherms. The results show that the selectivity towards CO2 and CO can be tuned by the carboxylato ligand, increasing its value with increasing length of the aliphatic chain. These selectivity values are relatively high in all compounds, especially for compound 3 in which the pore narrowing promoted by the lengthening of the aliphatic chain favours a preferential adsorption of CO2 and CO, leading to one of the highest values computed for MOFs to date. Moreover, the high affinity towards CO2 and CO, and the marked lowering of the selectivity with increasing pressure observed in compound 3 is explained on the basis of the analysis of the potential energy maps obtained by the simulations, which reveals two different adsorption sites.
Electrocatalytic Oxidation and Determination of Hydrazine at an AuCu Nanoparticles – Graphene – Ionic Liquid Composite Film Coated Glassy Carbon Electrode
Authors: Shang Lei , Zhao Faqiong , Zeng Baizhao
Published: November 2012

Gold‐copper alloy nanoparticles (AuCu NPs) were electrodeposited on a graphene – ionic liquid composite film (EGN‐IL). The AuCu NPs showed high electrocatalysis to the oxidation of hydrazine with a catalytic reaction rate constant of about 5.0×104 mol/Ls. In phosphate buffer solutions (pH 6.8) the oxidation current of hydrazine at 0.15 V (vs. SCE) at the resulting electrode (AuCuEGN‐IL/GCE) was linear to its concentration in the range of 0.2–110 µM with a sensitivity of 56.7 µA/mM, and the detection limit was 0.1 µM (S/N=3). The electrode was successfully applied to the determination of waste water.