ELEMENTS OF DNA-TECHNOLOGY FORMING QUALITY AND SAFE RAW MATERIALS
Authors:   Researcher, Candidate of Biological Science, V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, All-Russian Scientific Research Institute of Dairy Industry, Moscow, Russia, Gilmanov Khamid Khalimovich,  ,   gilmanov.xx@mail.ru,   https://orcid.org/0000-0001-7053-6925, Tyulkin Sergey Vladimirovich,  ,   Senior Researcher, Doctor of Biological Science, V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russia; tulsv@mail.ru; https://orcid.org/0000-0001-5379-237X, Vafin Ramil Rishadovich,  ,   Senior Researcher, Doctor of Biological Science, Professor of RAS, All-Russian Scientific Research Institute of Brewing, Non-Alcoholic and Wine Industry – branch of V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Leading Researcher, All-Russian Scientific Research Institute of Dairy Industry, Moscow, Russia; vafin-ramil@mail.ru; https://orcid.org/0000-0003-0914-0053, Galstyan Aram Genrikhovich,  ,   Acting Director, Doctor of Technical Science, Academician of RAS, All-Russian Scientific Research Institute of Dairy Industry, Moscow, Russia; 9795029@mail.ru; https://orcid.org/0000-0002- 0786-2055, Ryabova Anastasia Evgenyevna,  ,   Senior Researcher, All-Russian Scientific Research Institute of Brewing, NonAlcoholic and Wine Industry – branch of V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russia; anryz@hotmail.com; https://orcid.org/0000-0002-5712-2020, Semipyatny Vladislav Konstantinovich,  ,   Senior Researcher, All-Russian Scientific Research Institute of Brewing, Non-Alcoholic and Wine Industry – branch of V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russia; semipyatniy@gmail.com; https://orcid.org/0000-0003-1241-0026, Khurshudyan Sergey Azatovich,  ,   Leading Researcher, Doctor of Technical Science, Professor, All-Russian Scientific Research Institute of Brewing, Non-Alcoholic and Wine Industry – branch of V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russia; xsa020149@rambler.ru; https://orcid.org/0000-0001-7735-7356, Pryanichnikova Nataliya Sergeevna,  ,   Senior Researcher, Candidate of Technical Science, All-Russian Scientific Research Institute of Dairy Industry, Moscow, Russia; pryanichnikova@vnimi.org; https://orcid.org/0000-0003-1304-1517
Published: October 2020

It is known that cows high milk productivity is associated with decrease in resistance to various diseases, including bovine leukosis, in resistance formation to which the BoLA-DRB3 gene plays role, whose alleles are associated with resistance (R-alleles *7, *11, *23, *28), sensitivity (S-alleles *8, *16, *22, *24) or are defined as neutral (N) in relation to the disease. Researchers also established association of BoLA-DRB3-alleles *8, *11, *23 with an increased milk yield volume, and the *22 allele - with reduced milk yield volume. The aim of research was to study associative communication of servicing bulls BoLA-DRB3 genotypes groups with their breeding value by female ancestor’s dairy productivity indicators. As a result, we studied associative communication of servicing bulls BoLA-DRB3 genotypes groups with their breeding value by female ancestor’s dairy productivity indicators with identification of reduced milk productivity with genetic resistance to bovine leukemia virus infection and bovine leukosis disease relationship, as well as observation of positive correlation between increased milk productivity and genetic predisposition to increased milk yield volumes. The obtained information will be taken into account in breeding during dairy herds reproduction with genetic resistance to bovine leukosis.