bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effects of Modelling Strategies on Responses of Inventory Models
Authors: White Anthony S. , Censlive Michael
Published: December 2016

This paper describes methods to model inventories from the APVIOBPCS family. It aims to examine the limits of modelling approaches within control-theoretic models using the Simulink package. Discrete and continuous time models were considered together with a finite pipeline delay and the Forrester exponential delay, in continuous and sampled data representation. The main effect of using a finite delay is to deepen the stock-out and increase the required order rate compared with the same response observed with an exponential form delay. Total time for recovery is similar with all models. The discrete performances are close to the continuous representation for a smaller review period. Results presented here illustrate that the various forms of control-theoretic models present similar step response results irrespective of simulation technique used provided they have the same delay type. However, the gains required for minimum cost are substantially different for each delay form and modelling technique used.
Adolescents' Experiences of Cyberbullying
Authors: Gao Minghui , Zhao Xu , McJunkin Mark
Published: December 2016

This paper reports a multi-method study that investigated adolescents' experiences of cyberbullying. Sixty-one students (grades 10-12) responded to a survey that requires answers of both quantitative and qualitative nature. Quantitative data were statistically analyzed to understand frequencies and compare gender and grade differences. Qualitative data were coded to identify themes. Results suggest that a substantial portion of adolescents have experienced cyberbullying of various types. Significant gender differences exist in cyberstalking, with girls being more likely than boys to be subject to cyberstalking. Significant grade related differences exist in cyberstalking and exclusion, with 12th graders more likely to be victims of cyberstalking and exclusion than 10th and 11th graders. The majority of adolescents are unwilling to report cyberbullying experiences to adults due to reasons including lack of awareness or underestimating the negative effect of cyberbullying, fear of adults' overreaction, and the desire to deal with the problem by themselves.
Age Detection Through Keystroke Dynamics from User Authentication Failures
Authors: Tsimperidis Ioannis , Rostami Shahin , Katos Vasilios
Published: December 2016

In this paper an incident response approach is proposed for handling detections of authentication failures in systems that employ dynamic biometric authentication and more specifically keystroke user recognition. The main component of the approach is a multi layer perceptron focusing on the age classification of a user. Empirical findings show that the classifier can detect the age of the subject with a probability that is far from the uniform random distribution, making the proposed method suitable for providing supporting yet circumstantial evidence during e-discovery.
Multidimensional Model Design using Data Mining
Authors: Bimonte Sandro , Sautot Lucile , Journaux Ludovic , Faivre Bruno
Published: December 2016

Designing and building a Data Warehouse (DW), and associated OLAP cubes, are long processes, during which decision-maker requirements play an important role. But decision-makers are not OLAP experts and can find it difficult to deal with the concepts behind DW and OLAP. To support DW design in this context, we propose: (i) a new rapid prototyping methodology, integrating two different DM algorithms, to define dimension hierarchies according to decision-maker knowledge; (ii) a complete UML Profile, to define a DW schema that integrates both the DM algorithms; (iii) a mapping process to transform multidimensional schemata according to the results of the DM algorithms; (iv) a tool implementing the proposed methodology; (v) a full validation, based on a real case study concerning bird biodiversity. In conclusion, we confirm the rapidity and efficacy of our methodology and tool in providing a multidimensional schema to satisfy decision-maker analytical needs.
Exploring the Impact of Learning Styles on the Acceptance of Open Learner Models in Collaborative Learning
Authors: Sek Yong Wee , Deng Hepu , McKay Elspeth , Qian Minghui
Published: December 2016

This study investigates the relationship between learners' learning styles and the acceptance of open learner models for information sharing in collaborative learning. Based on a survey of 240 undergraduate students in a Malaysian university, the study explores the relationship between learning styles and the acceptance of open learner models for information sharing using a chi-square test. An independent t-test is conducted to investigate the gender difference on the acceptance of open learner models. The result reveals that there is no association between learners' learning styles and the acceptance of open learner models for information sharing. It shows that there is no difference between genders on the acceptance of open learner models. Such findings can assist open learner models designers to apply appropriate instructional design strategies in developing sustainable collaborative learning.
From a FabLab towards a Social Entrepreneurship and Business Lab
Authors: Guerra Alicia Guerra , de Gómez Lyda Sánchez
Published: December 2016

Social and institutional demands, in addition to the increased socioeconomic development of territories, advocate the creation of a more current, more integrated and larger university which, while continuing to teach technical knowledge, also teaches values. This would enable the university to respond to the countless challenges that are currently created by citizens in the form of social needs. The aim of this study is to explore the possibilities of creating value in a university FabLab in order to subsequently use this value as a vehicle for practical education in values and technical abilities in relation to the management of 21st century organisations. This materialises in a teaching initiative based on FabLab and that is suggested for computer engineering (University of Extremadura, Spain). After positioning university FabLabs in the digital age, detailing their potential for creating value, and describing this educational initiative, some closing conclusions will be made.
The Economic Cost of Implementing Maternal and Neonatal Death Review in a District of Bangladesh
Authors: Biswas Animesh , Halim Abdul , Rahman Fazlur , Eriksson Charli , Dalal Koustuv
Published: December 2016

Introduction

Maternal and neonatal death review (MNDR) introduced in Bangladesh and initially piloted in a district during 2010. MNDR is able to capture each of the maternal, neonatal deaths and stillbirths from the community and government facilities (hospitals). This study aimed to estimate the cost required to implement MNDR in a district of Bangladesh during 2010-2012.

Materials and methods

MNDR was implemented in Thakurgaon district in 2010 and later gradually extended until 2015. MNDR implementation framework, guidelines, tools and manual were developed at the national level with national level stakeholders including government health and family planning staff at different cadre for piloting at Thakurgaon. Programme implementation costs were calculated by year of costing and costing as per component of MNDR in 2013. The purchasing power parity conversion rate was 1 $INT = 24.46 BDT, as of 31st Dec 2012.

Results

Overall programme implementation costs required to run MNDR were 109,02,754 BDT (445,738 $INT $INT) in the first year (2010). In the following years cost reduced to 8,208,995 BDT (335,609 $INT, during 2011) and 6,622,166 BDT (270,735 $INT, during 2012). The average cost per activity required was 3070 BDT in 2010, 1887 BDT and 2207 BDT required in 2011 and 2012 respectively. Each death notification cost 4.09 $INT, verbal autopsy cost 8.18 $INT, and social autopsy cost 16.35 $INT. Facility death notification cost 2.04 $INT and facility death review meetings cost 20.44 $INT. One death saved by MNDR costs 53,654 BDT (2193 $INT).

Conclusions

Programmatic implementation cost of conducting MPDR give an idea on how much cost will be required to run a death review system for a low income country settings using government health system.
Prevalence of Diabetes in the 2009 Influenza A (H1N1) and the Middle East Respiratory Syndrome Coronavirus: A Systematic Review and Meta-Analysis
Authors: Badawi Alaa , Ryoo Seung Gwan
Published: December 2016

Over the past two decades a number of severe acute respiratory infection outbreaks such as the 2009 influenza A (H1N1) and the Middle East respiratory syndrome coronavirus (MERS-CoV) have emerged and presented a considerable global public health threat. Epidemiologic evidence suggests that diabetic subjects are more susceptible to these conditions. However, the prevalence of diabetes in H1N1 and MERS-CoV has not been systematically described. The aim of this study is to conduct a systematic review and meta-analysis of published reports documenting the prevalence of diabetes in H1N1 and MERS-CoV and compare its frequency in the two viral conditions. Meta-analysis for the proportions of subjects with diabetes was carried out in 29 studies for H1N1 ( n=92,948) and 9 for MERS-CoV ( n=308). Average age of H1N1 patients (36.2±6.0 years) was significantly younger than that of subjects with MERS-CoV (54.3±7.4 years, P<0.05). Compared to MERS-CoV patients, subjects with H1N1 exhibited 3-fold lower frequency of cardiovascular diseases and 2- and 4-fold higher prevalence of obesity and immunosuppression, respectively. The overall prevalence of diabetes in H1N1 was 14.6% (95% CI: 12.3-17.0%; P<0.001), a 3.6-fold lower than in MERS-CoV (54.4%; 95% CI: 29.4-79.5; P<0.001). The prevalence of diabetes among H1N1 cases from Asia and North America was ∼two-fold higher than those from South America and Europe. The prevalence of diabetes in MERS-CoV cases is higher than in H1N1. Regional comparisons suggest that an etiologic role of diabetes in MERS-CoV may exist distinctive from that in H1N1.
Monitoring Polypharmacy in Healthcare Systems through a Multi-Setting Survey: Should We Put More Attention on Long Term Care Facilities?
Authors: Arnoldo Luca , Cattani Giovanni , Cojutti Piergiorgio , Pea Federico , Brusaferro Silvio
Published: December 2016

Background

Polypharmacy is a main issue of patient safety in all healthcare settings (i.e. increase adverse drug reactions and incidence of drug-drug interactions, etc.). The main object of the study was to evaluate the prevalence of polypharmacy and the appropriateness of drugs prescriptions in the regional health system (RHS) of Friuli Venezia-Giulia Region, Italy.

Design and methods

We carried out a point prevalence study in May 2014; 1582 patients ≥65 years were included from: 14 acute hospitals, 46 Long Term Care Facilities (LTCFs) and 42 general practitioners’ (GPs) clinics. Data analysis included the evaluation of potentially inappropriate prescriptions (PIPs) taking Beers criteria as a reference.

Results

Patients in therapy with 10 drugs or more were 13.5%: 15.2% in hospitals, 9.7% in GPs’ clinics and 15.6% in LTCFs. According to Beers criteria we identified 1152 PIPs that involved globally almost half of patients (46.0%): 41.9% in hospitals, 59.6% in LTCFs and 37.0% in GP's clinics. The 53.9% of patients received at least one mainly kidney excreted drug; for these patients the evaluation of serum creatinine was overall present in the 87.7% (747/852): 96.4% in hospital ones, 87.5% in GPs’ clinics and 77.8% in LTCFs. LTCFs residents were significantly (P<0.05) more exposed to PIPs and less monitored for the renal function.

Conclusions

A reliable estimation of the phenomenon in all the main healthcare settings is a necessary prerequisite to set tailored policies for facing polypharmacy within a RHS; the results showed the necessity to put a special attention on LTCFs.
Are Food Labels Effective as a Means of Health Prevention?
Authors: Viviana Viola Gaia Claudia , Bianchi Francesca , Croce Elia , Ceretti Elisabetta
Published: December 2016

Chronic diseases related to unbalanced and unhealthy eating habits have definitely become one of the major issues of modern age, not only in western countries but also in those ones where rapid economic growth has increased global prosperity levels. In order to avoid medical systems to collapse under excessive costs, International and Public Organizations strongly support health policies that aim to make people shift towards wholesome dietary patterns, also encouraging the use of food-labels to choose healthier products. To evaluate the consumers’ knowledge and perception about food-labels a brief questionnaire was developed and shared on Facebook between January-March 2016. Most of the participants were young adults with higher education. They declared to do their shopping at least once a week, reading the food-labels quite often. Despite owing limited knowledge in basic nutrition principles and food-labelling they were generally able to recognize healthier products looking over their nutritional fact tables. Anyway, on average, what they care the most about the products they purchase is the global quality level rather than the nutritional values. In order to induce the whole population to use food label as an effective self-protection tool, more efforts should be done to improve their knowledge on nutrition fundamentals and basics about food labelling, because that would make them able to take safer and more conscious choices as regards their own health.
Geological and geochemical data from Mackenzie Corridor. Part V: New XRD data from Devonian cores and mineralogical characterization of mudrock units
Authors: Kabanov P , Percival J B , Bilot I , Jiang C
Published: December 2016

Mineralogical surveys are an important part of shale reservoir studies. New results, based on X-ray diffraction analyses (XRD), are reported here for 101 core samples from three wells, mostly from organic-rich mudrocks of the Horn River Group (HRG) in Mackenzie
Plain area. The combined NTGS-GSC XRD database has sufficient resolution for robust mineralogical characterization of stratigraphic units. The Canol Formation has the highest quartz (82% median) and the lowest clay content (7% median). Clays in the HRG are dominated by illite. The Hare
Indian and lower Canol formations are variably calcareous and dolomitic; the upper Canol is dolomitic but non-calcareous; basal Imperial shales are sideritic-dolomitic and non-calcareous. More accurate characterization can be achieved by resolving issues between GSC and NTGS correlation of
stratigraphic units. New XRD data are also used to characterize the Hume-HRG contact (a drowning unconformity) in Kugaluk N-02 well of northern Anderson Plain.
Thymoma masquerading as transfusion dependent anemia
Authors: Muzamil Javvid , Shiekh Aejaz Aziz , Bhat Gull Mohammad , Lone Abdul Rashid , Bhat Shuaeb , Nabi Firdousa
Published: December 2016

Pure red cell aplasia (PRCA) is a known entity in clinical medicine. Patients are often transfusion dependent for their whole life. Ascertaining its etiology is always a herculean task. We received a similar transfusion-dependent patient, who on evaluation was found to have thymoma as an etiological factor. Thymoma presenting as PRCA is seen in 2%–5% patients and evaluating PRCA for thymoma is seen in 5%–13% patient. As per the WHO histopathological classification, thymoma has six types and Type A is associated with PRCA and Type B is associated with myasthenia gravis. This correlation was not seen in our patient, who had Type B thymoma. Surgical resection of thymus improves 30% of PRCA and rest needs immunosuppression. Our patient was not the surgical candidate, and hence he was put on chemotherapy.
Clinicopathological profile of gastrointestinal lymphomas in Kashmir
Authors: Khuroo Mehnaaz Sultan , Khwaja Summyia Farooq , Rather Ajaz , Hassan Zhahid , Reshi Ruby , Khuroo Naira Sultan
Published: December 2016

Background: The histological categorization of lymphoma has been a source of controversy for many years for both clinicians and pathologists. Clinicopathologic information of gastrointestinal lymphomas in Indian subcontinent is lacking. We studied histopathological spectrum of Primary Gastrointestinal Lymphomas (PGIL) and attempted to classify the G.I. lymphomas based on the recent WHO classification in to major histological types and immunological categories. Material and Methods: This study was done to evaluate the clinicopathological pattern of 100 cases with a histopathological diagnosis of primary gastrointestinal lymphoma at a tertiary care hospital. All patients of primary gastrointestinal lymphomas were included with the help of medical records over a 11-years period that is, January 2005 to December 2015. Results: The study included 100 cases (60 males, 40 females; mean age 51.43 years; age range 4.5-90 years) . The disease involved stomach in 82 (82%), small intestine in 8 (8%), large bowel and rectum in 8 (8%), gall bladder in 1 (1%) and oesophagus in 1 (1%). 82 (82%) of the 100 cases were Diffuse Large B cell lymphomas; 12 (12%) were Extra Nodal Marginal Zone Lymphomas (ENMZL of MALT type) 2 (2%) IPSID 2 (2%) of Mantle cell lymphoma morphology, 1 (1%) Burkitt's and 1(1%) enteropathy associated T cell lymphoma. The commonest presenting symptom was abdominal pain. 99 (99%) of 100 tumours were classified as B-cell lymphomas immunohistochemically and majority exhibited monoclonal light chain restriction on kappa/lambda staining. In addition; Burkitt's lymphoma showed positivity for CD 10. One tumour (1%) showed positivity for T-cell markers. The data demonstrated that primary GI NHL is more common among males, mainly in their fifth decade. Abdominal pain is the most common presenting symptom, with stomach being the most commonly involved site. Diffuse large cell lymphoma is the most frequent histologic subtype, followed by extranodal marginal-zone B cell lymphoma (MALT type). H. Pylori infection was observed in cases with low grade MALT lymphomas. Striking was the observation of two cases of IPSID (a disease commonly found in Mediterranean countries) and one case of enteropathy associated T cell lymphoma. Conclusion: EGD, imaging, light microscopic examination and immunohistochemical workup for B and T cell markers and staining for light chains to assist documentation of monoclonality are of precise diagnostic value in gastrointestinal lymphomas and form a part of the diagnostic workup.
Metabolic toxicities in patients undergoing treatment for nonhematological malignancy: A cross-sectional study
Authors: Gupta Subhash , Haresh Kunhi Parambath , Roy Soumyajit , Kashyap Lakhan , Adhikari Narayan , Pandey Rambha , Sharma Dayanand , Julka Pramod Kumar , Rath Goura Kishor
Published: December 2016

Objectives: The objective of this study was to evaluate the prevalence of metabolic toxicities in patients with different nonhematological malignancies admitted in oncology ward of a tertiary cancer care center while on treatment. Methods: We did this cross-sectional study over a period of 7 months (January–July 2013) for all adult patients (n = 280) who, while undergoing anti-cancer therapy at our center, got admitted to our oncology inpatient ward with metabolic toxicity. Grading of toxicity was done using National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0. Results: A total of 46 events of metabolic toxicities were noted in 31 patients over this period. The most common of them was hyperglycemia (n = 10). The others were hypokalemia (n = 9), hyponatremia (n = 9), hypernatremia (n = 5), hyperkalemia (n = 5), tumor lysis syndrome (n = 4), hypercalcemia (n = 2), and grade ≤2 hypomagnesemia (n = 2). Majority of the patients were asymptomatic (n = 26). However, death occurred in five patients. Treatment interruptions took place in 19 patients. Age ≤40 years (P = 0.03), Eastern Cooperative Oncology Group performance status ≥2 (P = 0.023), history of addiction (P = 0.02), comorbidities (P = 0.037) were associated with increased risk of having metabolic toxicities on univariate analysis. While on multivariate analysis, only age, performance status, and history of addiction retained their statistical significance. Age ≤40 years (P = 0.02), use of more than one modality of treatment (P = 0.013), and hyperglycemia (P = 0.037) were associated with higher risk of death. Conclusion: Metabolic toxicities are common phenomena among cancer patients, especially those with young age, comorbidities, and having history of addictions. In young age, they might even be fatal, especially when they are treated with combined modality of treatment.
Managing metastatic renal cell carcinoma-challenges, pitfalls, and outcomes in the real world
Authors: Kumar Karnam Ashok , Sadashivudu Gundeti , Krishnamani K V , Linga Vijay Gandhi , Maddali Lakshmi Srinivas , Digumarti Raghunadha Rao
Published: December 2016

Introduction: Renal cell carcinoma (RCC) is the most common cancer of the kidney accounting for 85% of renal tumors. Metastatic RCC (mRCC) had a poor prognosis and with the introduction of tyrosine-kinase inhibitors, such as sunitinib, pazopanib the outcomes improved. There is only one study reported from India on the use of sunitinib in mRCC. We present our analysis of mRCC and use of sunitinib at our institute over 5 years. Materials and Methods: All patients with mRCC receiving sunitinib were analyzed with respect to patient characteristics, response, toxicity, and outcomes. Results: A total of 108 patients were seen during the study period. The male to female ratio was 9.8:1. The median age of patients at presentation was 58 years (range: 15–80 years). Of the 108 patients, 68.51% had metastatic disease at initial presentation. The most common sites of metastases were lung followed by bone. Of the 97 patients eligible for sunitinib, only 76 received at least one cycle of sunitinib, out of which only 48 received further cycles (range: 2–36). The median progression-free survival (PFS) and overall survival (OS) in our patients were 10.2 and 28.2 months, respectively. The most common adverse effect noticed in our population was mucositis followed by hand-foot syndrome. Conclusion: Sunitinib is an option for the treatment of mRCC and shows a good PFS in Indian patients. Median OS and PFS in this study are similar to other reported studies despite the presence of poor risk factors in the patient population. The pitfall in this study is significant attrition due to poor compliance to treatment and follow-up, which is a major factor in the clinic thereby compromising outcomes.
Protection behaviors for cytotoxic drugs in oncology nurses of chemotherapy centers in Shiraz hospitals, South of Iran
Authors: Abbasi Khadijeh , Hazrati Maryam , Mohammadbeigi Abolfazl , Ansari Jasem , Sajadi Mahboubeh , Hosseinnazzhad Azam , Moshiri Esmail
Published: December 2016

Context: The use of antineoplastic agents for the treatment of cancer is an increasingly common practice in hospitals. As a result, workers involved with handling antineoplastic drugs may be accidentally exposed to these agents, placing them at potential risk for long-term adverse effects. This study aimed to determine the occupational protection status of clinical nursing staff exposed to cytotoxic drugs. Subjects and Methods: The study was designed as an analytic descriptive survey. The research settings took place in six centers of chemotherapy in Shiraz, Iran. The participants were 86 nurses who worked in oncology units and administered cytotoxic drugs. Data were collected using a questionnaire and a checklist which was developed by the investigators to determine occupational protection status of clinical nursing staff exposed to cytotoxic drugs. Percentage calculations and the independent samples t-test were used to see the general distribution and analysis of data. To statistically analyze of the data, SPSS software (version 16) was applied. Results: The mean age of participants was 30.52 ± 6.50 years and 66.27% of the nurses worked on inpatient oncology wards. The mean practice score was 21.1 ± 3.76 that ranged from 12.5 to 31. The independent samples t-test showed the outpatient nurses were weaker in practice (17.2 ± 2.52) in comparison with university hospitals (23.35 ± 3.02, P< 0.001). Occupational protection status of clinical nursing staff exposed to cytotoxic drugs especially during administration and disposal of medicines was poor and rarely trained with this subject and was observed under the standard conditions. Conclusions: There is deficiency in the understanding and related protection practices of clinical nursing staff vocationally exposed to cytotoxic drugs. It is recommended that all clinical nursing staff should receive full occupational protection training about these matters and the authorities provide standard conditions of oncology wards.
Cognizance and utilization about breast cancer screening among the health professional female students and staffs of University Kuala Lumpur, Royal College of Medicine Perak, Malaysia
Authors: Haque ATM Emdadul , Mohd Hisham Muhammad Afif Bin , Ahmad Adzman Noor Azwa Laili Binti , Azudin Nur Atiqah Binti , Shafri Nursakinah Binti , Haque Mainul
Published: December 2016

Background: Breast cancer (BC) is a major life-threatening problem and a global concern including Malaysia. BC is an equal threat for both developing and developed countries. The aim of this study was to determine the relationship between sociodemographic factors with knowledge, attitude, and perception on BC screening among the females of University Kuala Lumpur, Royal College of Medicine Perak (UniKL RCMP). Materials and Methods: This cross-sectional study was conducted from 2015 to 2016. The populations included were the students and staff of UniKL RCMP. The simple sampling method was used and a set of questionnaire was prepared and distributed to the participants who were willing to participate. The data were analyzed by using the SPSS version 17. Results: Of the 220 only 203 questionnaires were returned. Nearly 87.7% of participants indicated genetic factors as the cause of BC, followed by exposure to carcinogenic and X-ray. Excessive smoking (54.2%) and sedentary lifestyle (52.2%) were the risk factors of the BC. 100% of participants thought that breast self-examination (BSE) is important to detect a breast lump and most of them (76.8%) knew what a mammogram is but only 2.0% went for a mammogram. Chemotherapy (71.9%) and surgery (71.9%) were treatments options according to study participants. Nearly 91.1% agreed that regular mammogram could help to detect BC at an early stage. Nearly 88.2% thought BC is not easily curable. Finally, for the attitude on BC screening, most of them knew how to perform BSE (69.0%) with the frequency of 36.0% doing it once a year. Conclusions: The majority of the participants found the good knowledge on BC and on how to perform BSE. Although most of them knew what a mammogram is, only a few have gone for it since perhaps it is recommended for those who are above 50-year-old. Therefore, researchers believe and trust that there is an urgent need of state-funded multicenter study to prevent and early diagnosis of BC in Malaysia.
Hailey-Hailey disease
Authors: Donadel Kathia Werlang , Donadel Matheus Werlang , Donadel Rafael Werlang , dos Santos Bruna Orquiza
Published: December 2016

Hailey-Hailey disease, also known as familial chronic benign pemphigus, is characterized by flaccid blisters and erosions, especially in the axillary and inguinal areas. Friction associated with local factors such as heat, moisture, microbial colonization, and secondary infections induce the typical appearance of the lesions, especially in intertriginous areas. Traditionally, the treatment is done with corticosteroids associated with topical or systemic antibiotics. We report the case of a patient with the disease presenting in the inguinal region, which has made use of different conventional drug treatments for 20 years without results. Treatment with application of botulinum toxin type A showed a significant improvement after about 20 days. The satisfactory response has been linked to decreased local sweating caused by botulinum toxin. which would lead to a less local irritation factors and lower colonization of microrganisms.
Nicolau Syndrome
Authors: Tiwary Anup Kumar , Aggarwal Rohit K
Published: December 2016

Nicolau syndrome, also known as embolia cutis medicamentosa or livedoid dermatitis, is a rare cutaneous adverse drug reaction seen at the site of injection of some particular drugs. It was first reported by Freudenthal in 1924 and Nicolau in 1925 as an adverse effect of bismuth salts used in syphilis. Typically, this syndrome is clinically manifested by intense burning or stabbing pain at the site of injection and retiform hemorrhagic patches with or without vesiculations and ulceration with a variable degree of tissue necrosis. To the best of our knowledge, <50 cases of Nicolau syndrome have been reported in medical literature which occurred following intramuscular administration of diclofenac sodium. Here, we report a 26-year-old female typically presenting with pathognomic signs and symptoms of NS after taking intramuscular injection of diclofenac.
Efeito das transformações antrópicas às margens do rio Una, Taubaté, São Paulo, Brasil
Authors: Perim Marli Aparecida , Alves Cocco Maria Dolores
Published: December 2016

This study sought to support the mapping of occupied areas on the margin of rivers through the use of geoprocessing imaging technologies combined with the application of indices that measure the effects of the anthropic transformations in the environment, in order to verify the environmental degradation. The Anthropic Transformation Index is demonstrably efficient for space-time analyses on river basins and at environmental protection areas. In order to develop a data base to support public policies related to the preservation of the Una River Basin, this article presents the effects of the anthropic actions in the years 1962 to 2014, in the registry district of Taubaté, in the Vale do Paraíba Metropolitan Region. In order to collect data using photos and aerial images of the territory, geo-referencing and vectorization were performed by the QGIS program, which enabled quantification of the occupation and land use. Five occupational categories types had been identified in the area: watercourses, riparian forest, field or pasture, denser forest and urbanization. Afterwards, the ITA was applied and the index 5.5 was obtained, which indicates a degraded area, based on the percentage of land use and occupation. It was concluded that the greatest change occurred in a 52-year time span, in the landscape of registry district, where a marked anthropic pressure was observed.it is the significant anthropic pressure, close to the watercourses, towards the Una River Basin, in the city of Taubaté, in the state of São Paulo.
O conhecimento de produtores rurais do município de Arealva, SP, Brasil sobre as regras de uso dos agrotóxicos
Authors: De Melo Pereira Rafael , Correa de Araujo Marialdo , Mascarette Labinas Adriana
Published: December 2016

Since the 1970s, the environmental consequences of the intensive use of agrochemicals have aroused the interests and concerns of technicians, scientists, and government agencies because possible contaminations caused by these substances. However, a major problem to be considered is the correct destination of pesticide containers after the use of the products, a liability resulting from the intensification of the use of pesticides formerly treated as common waste, or even dumped in the environment. This paper discussed the results obtained in the work carried out in Arealva City in São Paulo State, approaching the importance of the GEDAVE System (Animal and Plant Protection Management System), from use to the return of empty packaging, promoting better monitoring of the use and minimizing risks of this products. It was observed that farmers know the general rules that involve the rational use of agrochemicals, however, they still have difficulties in the practical applications regarding the storage in the rural property and the logistics of returning empty containers. So it was observed the necessity of the itinerant gathering with frequency, like tool that will solve the logistic difficulties reported.
La comunicación pública de los alcaldes a través de Twitter en periodo electoral
Authors: López de Ayala López María Cruz , García Beatriz Catalina , Fernández Fernández José Gabriel
Published: December 2016

Se analiza el uso de Twitter como canal de comunicación institucional de los alcaldes de capitales de provincia y presidentes de ciudades autónomas en España durante el periodo preelectoral, electoral y una semana después de los comicios municipales de mayo de 2015. Metodología. Un análisis de contenido de los perfiles que los representantes municipales que actúan bajo las siglas de PP y PSOE tienen activos en esta plataforma de microblogging examina la actividad de los alcaldes y la de sus seguidores. Resultados y conclusiones. Destaca el uso partidista y/o electoralista que hacen los alcaldes de sus cuentas institucionales; el interés que suscita entre los usuarios los mensajes relativos al ámbito local y que se manifiesta en la difusión en sus cuentas, su selección como favoritos y realización de comentarios; se pone de manifiesto el respeto por parte de los titulares de las cuentas a la jornada de reflexión.
Los menores como usuarios creadores en la era digital: del prosumer al creador colaborativo. Revisión teórica 1972-2016
Authors: Herrero-Diz Paula , Ramos-Serrano Marina , Nó Sanchez Javier
Published: December 2016

Este artículo presenta una revisión cronológica de las teorías que contemplan a los menores de edad como creadores de contenidos digitales. Marco teórico. Se han seleccionado todas aquellas que aportan una definición terminológica para describir su comportamiento en Internet. Conclusiones y discusión. Podemos afirmar que nos encontramos con numerosas etiquetas para denominar de forma distinta su presencia y participación en la red y que los expertos proponen establecer con ellas la existencia de nuevas generaciones de jóvenes, entre las que apenas transcurre el tiempo ni se produce un cambio sustancial en la manera de consumir o producir contenidos: generación WhatsApp, Twitter, selfie o Snapchat. Por ello nos preguntamos qué determina realmente que haya una nueva generación de jóvenes creadores de contenidos digitales y proponemos, frente al excesivo etiquetado, hablar de perfiles de usuarios, para lo que hacemos una recopilación de sus características en función del uso de la tecnología.
Política y vida privada en las elecciones al Parlamento Vasco de 2012. Estudio del formato “Un día con el candidato”
Authors: Ruiz San Miguel Francisco Javier , Galindo Arranz Fermín , Ruiz Blanco Sonia
Published: December 2016

Hoy la política ocupa un alto nivel de protagonismo, y no sólo centrado en el discurso político de dirigentes y partidos, sino en los aspectos más personales de los candidatos. Así, en los últimos tiempos, los políticos intentan mostrarse a un mayor nivel, tanto en el terreno oficial como en el más personal. Metodología. Se analiza exhaustivamente el contenido de las imágenes de los cuatro reportajes publicados sobre los candidatos. Resultados: Pese a los esfuerzos del medio por transmitir una denotación de equilibrio y neutralidad, en los cuatro reportajes observamos diferencias sustanciales en los géneros y estilos fotoperiodísticos, así como en el tratamiento lingüístico de las imágenes. Discusión. No se trata de ver cómo se percibe al candidato, sino cómo se representa, a través de los distintos aspectos medidos y analizados. Conclusión. Existe una clara discrepancia entre el relato textual y lo que nos cuentan las imágenes, creando así una disonancia cognitiva en los lectores.
Action planning intervention to identify how to improve selection processes for internships
Authors: Marin-Garcia Juan A. , González Eduardo , Carrasco Myriam , Ros Daniel
Published: December 2016

In this research into participatory action research, by a team formed by researchers and people in charge in various areas of several multinational companies, we reflected on the advantages and disadvantages of internships and we proposed a procedure for companies to improve the recruitment and selection of industrial engineers, while strengthening relationships between the university and companies, attracting students’ interest, improving their professional competences and providing evidence for their students’ real learning to degree managers at the same time.
Critically Reflective Pedagogical Model: a Pragmatic Blueprint for Enhancing Learning and Teaching in Construction Disciplines
Authors: Kamardeen Imriyas
Published: December 2016

University lecturers who aspire to provide an improved learning experience for their students continually, and be recognised for high quality teaching should embrace a critically reflective practice. Nonetheless, developing as a reflective lecturer is challenging, although there are pedagogical literatures as general guidelines. This study introduces a new pedagogical model of critically reflective practice to simplify the efforts for lecturers and to shorten their journey to becoming effective teachers. A two-phased action research strategy was adopted for the development and validation of the new model. The first phase operationalised the Brookfield’s four-lens framework to create a reflective teaching practice model, which was then validated with a case study in the second phase. The model offers a pragmatic blueprint for lecturers to build a career with sustained quality of teaching, which in turn translates into improved learning experiences for students.
test document
Authors: Abbott Scott
Published: December 2016

test doc abstract
Performance Test for the SIGMA Communication System
Authors: Jeong Seonyeong , Lee Hyojeong , Lee Seongwhan , Shin Jehyuck , Lee Jungkyu , Jin Ho
Published: December 2016

Scientific CubeSat with Instruments for Global Magnetic Fields and Radiations (SIGMA) is a 3-U size CubeSat that will be operated in low earth orbit (LEO). The SIGMA communication system uses a very high frequency (VHF) band for uplink and an ultra high frequency (UHF) band for downlink. Both frequencies belong to an amateur band. The ground station that communicates with SIGMA is located at Kyung Hee Astronomical Observatory (KHAO). For reliable communication, we carried out a laboratory (LAB) test and far-field tests between the CubeSat and a ground station. In the field test, we considered test parameters such as attenuation, antenna deployment, CubeSat body attitude, and Doppler frequency shift in transmitting commands and receiving data. In this paper, we present a communication performance test of SIGMA, a link budget analysis, and a field test process. We also compare the link budget with the field test results of transmitting commands and receiving data.
Installation of Neutron Monitor at the Jang Bogo Station in Antarctica
Authors: Jung Jongil , Oh Suyeon , Yi Yu , Evenson Paul , Pyle Roger , Jee Geonhwa , Kim Jeong-Han , Lee Changsup , Sohn Jongdae
Published: December 2016

In December 2015, we have installed neutron monitor at the Jang Bogo station in Antarctica. The Jang Bogo station is the second science station which is located at the coast (74° 37.4’S, 164° 13.7’E) of Terra Nova Bay in Northern Victoria Land of Antarctica. A neutron monitor is an instrument to detect neutrons from secondary cosmic rays collided by the atmosphere. The installation of neutron monitor at Jang Bogo station is a part of transferred mission for neutron monitor at McMurdo station of USA. Among 18 tubes of 18-NM64 neutron monitor, we have completed relocation of 6 tubes and the rest will be transferred in December 2017. Currently, comparison of data from both neutron monitors is under way and there is a good agreement between the data. The neutron monitor at Jang Bogo station will be quite useful to study the space weather when the installation is completed.
Mixing state of oxalic acid containing particles in the rural area of Pearl River Delta, China: implication for seasonal formation mechanism of Secondary Organic Aerosol (SOA)
Authors: Cheng Chunlei , Li Mei , Chan Chak K. , Tong Haijie , Chen Changhong , Chen Duohong , Wu Dui , Li Lei , Cheng Peng , Gao Wei , Huang Zhengxu , Li Xue , Fu Zhong , Bi Yanru , Zhou Zhen
Published: December 2016

Abstract. The formation of oxalic acid and its mixing state in atmospheric particulate matter (PM) were studied using a single particle aerosol mass spectrometer (SPAMS) in the summer and winter of 2014 in Heshan, a supersite in the rural area of the Pearl River Delta (PRD) region in China. Oxalic acid-containing particles accounted for 2.5 % and 2.7 % in total detected ambient particles in summer and winter, respectively. Oxalic acid was measured in particles classified as elemental carbon (EC), organic carbon (OC), elemental and organic carbon (ECOC), biomass burning (BB), heavy metal (HM), secondary (Sec), sodium-potassium (NaK) and dust. Oxalic acid was found predominantly mixing with sulfate and nitrate during the whole sampling period, likely due to aqueous phase reactions. In summer, oxalic acid-containing particle number and ozone concentration followed a very similar trend, which may reflect the significant contribution of photochemical reactions to oxalic acid formation. Furthermore, favorable in-situ pH (2–4) conditions were observed, which promote Fenton like reactions for efficient production of •OH in HM type particles. A mechanism in which products of photochemical oxidation of VOCs partitioned into the aqueous phase of HM particles, followed by multistep oxidation of •OH through Fenton like reactions to form oxalic acid is proposed. In wintertime, carbonaceous type particles contained a substantial amount of oxalic acid as well as abundant carbon clusters and biomass burning markers. The general existence of nitric acid in oxalic acid-containing particles indicates an acidic environment during the formation process of oxalic acid. Organosulfate-containing particles well correlated with oxalic acid-containing particles during the episode, which suggests the formation of oxalic acid is closely associated with acid-catalyzed reactions of organic precursors.
Skill and independence weighting for multi-model
assessments
Authors: Sanderson Benjamin , Wehner Michael , Knutti Reto
Published: December 2016

Abstract. We present a weighting strategy for use with the CMIP5 multi-model archive in the 4th National Climate Assessment which considers both skill in the climatological performance of models over North America as well as the inter-dependency of models arising from common parameterizations or tuning practices. The method exploits information relating to the climatological mean state of a number of projection-relevant variables as well as metrics representing long term statistics of weather extremes. The weights, once computed can be used to simply compute weighted means and significance information from an ensemble containing multiple initial condition members from co-dependent models of varying skill. Two parameters in the algorithm determine the degree to which model climatological skill and model uniqueness are rewarded; these parameters are explored and final values are defended with respect to the Assessment. The influence of model weighting on projected temperature and precipitation changes is found to be moderate, partly due to a compensating effect between model skill and uniqueness. However, more aggressive skill weighting and weighting by targeted metrics is found to have a more significant effect on inferred ensemble confidence in future patterns of change for a given projection.
StreamFlow 1.0: an extension to the spatially distributed snow model Alpine3D for hydrological modelling and deterministic stream temperature prediction
Authors: Gallice Aurélien , Bavay Mathias , Brauchli Tristan , Comola Francesco , Lehning Michael , Huwald Hendrik
Published: December 2016

Abstract. Climate change is expected to strongly impact the hydrological and thermal regimes of Alpine rivers within the coming decades. In this context, the development of hydrological models accounting for the specific dynamics of Alpine catchments appears as one of the promising approaches to reduce our uncertainty of future mountain hydrology. This paper describes the improvements brought to StreamFlow, an existing model for hydrological and stream temperature prediction built as an external extension to the physically based snow model Alpine3D. StreamFlow's source code has been entirely written anew, taking advantage of object-oriented programming to significantly improve its structure and ease the implementation of future developments. The source code is now publicly available online, along with a complete documentation. A special emphasis has been put on modularity during the re-implementation of StreamFlow, so that many model aspects can be represented using different alternatives. For example, several options are now available to model the advection of water within the stream. This allows for an easy and fast comparison between different approaches and helps in defining more reliable uncertainty estimates of the model forecasts. In particular, a case study in a Swiss Alpine catchment reveals that the stream temperature predictions are particularly sensitive to the approach used to model the temperature of subsurface flow, a fact which has been poorly reported in the literature to date. Based on the case study, StreamFlow is shown to reproduce hourly mean discharge with a Nash–Sutcliffe efficiency (NSE) of 0.82 and hourly mean temperature with a NSE of 0.78.
Using crowdsourced web content for informing water systems operations in snow-dominated catchments
Authors: Giuliani Matteo , Castelletti Andrea , Fedorov Roman , Fraternali Piero
Published: December 2016

Abstract. Snow is a key component of the hydrologic cycle in many regions of the world. Despite recent advances in environmental monitoring that are making a wide range of data available, continuous snow monitoring systems that can collect data at high spatial and temporal resolution are not well established yet, especially in inaccessible high-latitude or mountainous regions. The unprecedented availability of user-generated data on the web is opening new opportunities for enhancing real-time monitoring and modeling of environmental systems based on data that are public, low-cost, and spatiotemporally dense. In this paper, we contribute a novel crowdsourcing procedure for extracting snow-related information from public web images, either produced by users or generated by touristic webcams. A fully automated process fetches mountain images from multiple sources, identifies the peaks present therein, and estimates virtual snow indexes representing a proxy of the snow-covered area. Our procedure has the potential for complementing traditional snow-related information, minimizing costs and efforts for obtaining the virtual snow indexes and, at the same time, maximizing the portability of the procedure to several locations where such public images are available. The operational value of the obtained virtual snow indexes is assessed for a real-world water-management problem, the regulation of Lake Como, where we use these indexes for informing the daily operations of the lake. Numerical results show that such information is effective in extending the anticipation capacity of the lake operations, ultimately improving the system performance.