bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of chip compression ratio in turning of polyoxymethylene copolymer
Authors:   Faculty of Mechanical Engineering in Niš, University of Niš, Aleksandra Medvedeva 14, 18106 Niš, Serbia, Trifunović Milan , Madić Miloš ,   Faculty of Mechanical Engineering in Niš, University of Niš, Aleksandra Medvedeva 14, 18106 Niš, Serbia, Janković Predrag ,   Faculty of Mechanical Engineering in Niš, University of Niš, Aleksandra Medvedeva 14, 18106 Niš, Serbia
Published: December 2023

The turning process is influenced by a synergy of various parameters that affect the machining mechanisms and the resulting process efficiency. Among these factors, the evaluation of chip morphology is of paramount importance and can often be quantified by the chip compression ratio. This key figure serves as a quantitative measure of the overall plastic deformation and provides information about the energy expended during cutting and the friction behavior at the interface between the chip and the cutting tool. This research is specifically concerned with modeling and analyzing the chip compression ratio during dry turning of polyoxymethylene copolymer (POM-C) using a polycrystalline diamond (PCD) tool. The experimental setup comprised a face-centered, central compound test in which three main parameters — depth of cut, feed rate and cutting speed - were adjusted to each other. After conducting the turning experiments and collecting the measurement data, a second-order mathematical model was formulated to establish the relationship between the turning parameters and the chip compression ratio. Statistical analysis of the results revealed notable main effects of depth of cut and feed rate, a quadratic effect of depth of cut and an interaction effect between feed rate and cutting speed, all of which have a significant effect on the change in chip compression ratio.
Assessing the precision of machine tools through various measurement systems
Authors:   Faculty of Mechanical Engineering, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, Tešić Saša , Jotić Goran ,   Faculty of Mechanical Engineering, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, Čiča Đorđe ,   Faculty of Mechanical Engineering, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, Sredanović Branislav ,   Faculty of Mechanical Engineering, University of Banja Luka, Banja Luka, Bosnia and Herzegovina, Štrbac Branko ,   University of Novi Sad, Faculty of Technical Sciences, Trg Dositeja Obradovica 6, 21000 Novi Sad, Serbia., Ranisavljev Miloš ,   University of Novi Sad, Faculty of Technical Sciences, Trg Dositeja Obradovica 6, 21000 Novi Sad, Serbia.
Published: December 2023

Nowadays, machine tools have to meet high precision requirements when it comes to manufacturing parts that have to correspond exactly to the specified geometries. Achieving high precision and accuracy when machining parts is a growing challenge, especially as machine tool operating hours increase. This increasing challenge emphasizes the need for regular verification of machine tool accuracy. In this study, the accuracy of a three-axis milling center was investigated, analyzing different measurement systems suitable for evaluating the precision of machine tools. The main objective was to evaluate the feasibility of using faster and less expensive inspection methods and measurement systems without compromising the reliability of the evaluation process. The research included an investigation of two different measurement systems developed for the acquisition of machine tool accuracy data: a coordinate measuring machine equipped with a contact sensor and a 3D laser scanner. The aim of this comparative analysis is to identify optimal approaches to machine tool accuracy assessment that balance speed and affordability while ensuring the reliability and trustworthiness of the test results obtained.
Pediatrik makroorşidizm
Authors: Kapısız Alparslan , Eryılmaz Sibel , Türker Leyla Nur , Kaya Cem , Karabulut Ramazan , Türkyılmaz Zafer , Atan Ali , Sönmez Kaan
Published: December 2023

Macroorchidism is defined as an increase in testicular volume at least twice the normal for age. It is a rare condition and its exact incidence is unknown. Although macroorchidism is relatively rare, when it is seen, causes such as genetic, endocrine, neoplasm or testicular torsion should be investigated. With this review, information on diagnosis, treatment and follow-up will be given, especially in the presence of macroorchidism seen in children, by emphasizing possible causes, especially McCune-Albright, Fragile X syndromes and hypothyroidism. Keywords: macroorchism, children, McCune-Albright syndrome, Fragile-X syndrome, hypothyroidism
HIV-negatif hastada penil kaposi sarkomu: Olgu sunumu
Authors: Öztürk Abuzer , Ergin İsmail Emre , Asdemir Aydemir , Öztürk Nisa Begüm , Saygın Hüseyin
Published: December 2023

Kaposi sarcomas are inflammatory and vascular tumors and occur frequentiy in immunosuppressive patients. Herein, we present a case of Kaposi sarcomas in patient who has not infected with human immunodeficiency virüs (HIV) or received an immunosuppressive medication. Sixty-nine-year-old man was admitted to the hospital with violet nodular lesion in glans penis. The examination of excisionat biopsy of lesion revealed Kaposi sarcomas. The patient has been followed up without antitumor treatment and relapse for ten months. In conclusion, Kaposi sarcomas should be mind in differential diagnosis of non-specific lesion of penis. Keywords: Kaposi sarcoma, glans penis, treatment
Hematospermili hastaya yaklaşım
Authors: Tosun Halil , Gölbaşı Abdullah , Akınsal Emre Can , Sönmez Gökhan , Baydilli Numan
Published: December 2023

Hematospermia or hemospermia is defined as the presence of fresh or stale blood in the semen. Various factors can cause hematospermia, including infectious, inflammatory, iatrogenic, traumatic, anatomical, neoplastic, vascular, and systemic factors. It is most common in men under the age of 40 and the cause is usually benign; however, even a single episode of hematospermia requires basic diagnostic evaluation. The main purpose of the evaluation is to identify significant underlying or treatable causes of hematospermia and to reassure the patient if no causal factor is identified after full evaluation. This review aims to demonstrate the management of hematospermia, which includes detailed history, physical examination, appropriate laboratory examinations and diagnostic imaging, based on the underlying causes. Keywords: Hematospermia, analysis, semen, blood
Cinsiyet disforisi cerrahisinde ürolojik yaklaşım
Authors: Çınar Naci Burak , Çulha Mustafa Melih
Published: December 2023

Gender dysphoria is defined as a condition of discomfort and dissatisfaction arising from the inconsistency between a person’s gender identity and the sex assigned at birth. With the definition of gender dysphoria in the DSM-5, this condition has been redefined as gender diversity, moving away from terms like illness or disorder. In recent years, the increase in societal recognition and acceptance of transgender individuals has led to many requests for gender-affirming surgeries. Despite advances in vaginoplasty and phalloplasty surgical techniques over the past century, gender-affirming surgeries remain challenging and require a multidisciplinary approach. Given the intricate nature of these procedures, a thorough understanding of the anatomy, which has been established for proper comprehension and management of complications, is essential. These surgeries performed on the genital region fall within the field of urology anatomically and functionally. Keywords: gender dysphoria, sex reassignment surgery, urological approach
Prostat lazer cerrahileri sonrası erektil ve ejakülatuvar fonksiyonlar
Authors: Gölbaşı Abdullah , Tosun Halil , Akınsal Emre Can , Sönmez Gökhan , Baydilli Numan
Published: December 2023

Benign prostatic hyperplasia (BPH) is a common health condition in aging men resulting in lower urinary tract symptoms (LUTS) and poor quality of life. Until recently, transurethral prostatectomy (TUR-P) was considered the gold standard for prostate surgery, but prostate enucleation methods using advanced laser technologies have become a strong competitor to TUR-P and have become widely used. The effects of all surgical procedures performed for prostate on sexual functions have been the subject of many studies. In today’s world where quality of life is emphasized and technological advances are increasing, the search for treatment methods with minimal effect on sexual function in the surgical treatment of BPH has increased. In this review, the effects of laser surgeries in the treatment of BPH on erectile and ejaculatory function will be presented with the current literature. Keywords: benign prostatic hyperplasia, HOLEP, ThuFLEP, erectile function, ejaculatory function
Yield and Quality Traits of Black Cumin (Nigella sativa L.) Genotypes in Response to the Different Sowing Dates
Authors: Barut Muzaffer , Cavdar Asiye Sena , Tansı Leyla Sezen , Karaman Şengül
Published: December 2023

Black cumin has been used in many countries for the treatment of diseases such as cancer and diabetes, and for thousands of years as a spice, flavoring in products such as bread, and as a food preservative in pickles. Too much delay in the sowing of black cumin has a negative effect on plant growth. In order to determine the most suitable sowing dates for different black cumin genotypes, an experiment was conducted in the open-field conditions of the Eastern Mediterranean region of Türkiye at Çukurova University, for two years, in 2020 and 2021, in three different sowing dates (October 15th, November 01st, and November 15th) with three different black cumin genotypes (Çameli cultivar (G1), Adana population (G2) and Iraq population (G3)). The findings of this research demonstrated significant differences in the agronomic characteristics and overall quality of black cumin. The main components were p-cymene (51.45%-66.33%), trans-4-Methoxythujane (8.40%-11.90%), thymoquinone (0.11%-19.26%), γ-Terpinene (1.28%-9.09%), and limonene (2.93%-4.50%). The main fatty acids were determined as linoleic acid (53.97%-57.56%), oleic acid (20.98-26.40), and palmitic acid (13.73%-15.02%). Consequently, the low number of flowers and the high temperatures observed in May, along with the early spring frosts, negatively affected the fertilization of the flowers. The seed yield was adversely affected because some of the seeds could not mature.
Determination of Probiotic Viability in Yoghurts Produced with Acid Adapted Lactobacillus acidophilus ATCC 4356 and Bifidobacterium bifidum ATCC 11863 During Refrigerated Storage
Authors: Oğuz Şehriban , Andiç Seval , Badak Neşe , Demir Tekin
Published: December 2023

Microorganisms have various stress response systems to maintain their viability when exposed to different stress conditions. In this study, Lactobacillus acidophilus ATCC 4356 and Bifidobacterium bifidum ATCC 11863 strains, used in probiotic yoghurt production, were subjected to acid (lactic and hydrochloric acid) stress to induce acid tolerance response (ATR). Yoghurts produced with both acid-adapted and non-adapted strains were stored at +4°C for 21 days. During the storage period, the pH and titratable acidity values of the yoghurts were measured, and the viability levels of the probiotic strains in the yoghurts were determined. In all yoghurt groups, a decrease in pH values and an increase in titratable acidity were observed during storage. The highest viability levels of the probiotic strains were detected on the first day of storage. Lactic acid-adapted Lb. acidophilus ATCC 4356 and B. bifidum ATCC 11863 in yoghurt showed growth at a level of 8.08 ± 0.12 and 8.08 ± 0.09 log10 Cfu/g at the first day of storage, respectively. Additionally, hydrochloric acid-adapted Lb. acidophilus ATCC 4356 and B. bifidum ATCC 11863 in yoghurt exhibited growth at levels of 7.90 ± 0.08 and 5.99 ± 0.03 log10 Cfu/g, respectively. The viability of acid-adapted Lb. acidophilus ATCC 4356 and B. bifidum ATCC 11863 showed a decrease similar way to that of the control group (non-acid adapted) during the storage period.
National Innovation System and an Approach to Innovation Activities at the Scale of an Economic Sector: Some Theoretical Foundations
Authors: Ngoc Ca Tran , Thanh Tung Dang
Published: December 2023

Innovation is one of the important factors for rapid and sustainable economic and social development in an internationally competitive environment. Identifying and analyzing the national innovation system is a necessary need, moving towards building policy solutions to support Vietnam's national innovation system. However, at the scale and level of an economic industry, this connotation can and should be developed and applied according to the industry innovation system approach.

Keywords: National innovation system, sectoral innovation system, emerging innovation system, fragmented (dual) innovation system.
Innovating the Method of Determining the List of Science and Technology Tasks to Serve the Local Economy and Society: Case Study of Ninh Thuan Province
Authors: Van Duong Ngo , Dac Binh Minh Nguyen , Tien Dung Le , Quang Lam Vo , Anh Tuan Tran
Published: December 2023

The current method for determining the portfolio of scientific and technological tasks for Ninh Thuan province up to 2025 share some several similarities with the current approach, but also significant differences and innovations. Instead of annually announcing task orders, Ninh Thuan identifies priority tasks based on the directives and policies of the Party and the government as well as local practical needs. Subsequently, it formulates specialized resolutions regarding the direction and resources to establish a solid foundation for implementation. Simultaneously, it develops a list of scientific and technological tasks along the long-term value chain in stages to proactively engage local, central, and societal ideas and resources.

Keywords: Ninh Thuan, Innovation, methods, determining the list of science and technology tasks.
Oriental motifs and images in the works of K.D. Balmont: a cultural aspect.
Authors: Shashneva Ekaterina Nikolaevna , Val'kevich Svetlana Ivanovna , Maslov Viktor Georgievich , Mihailov Aleksei Aleksandrovich , Ershova Lyudmila Viktorovna , Astakhov Oleg Yur'evich , Romanova Karine Evgen'evna , Okeanskaya Zhanna Leonidovna
Published: December 2023

The article examines oriental motifs and images in the work of the poet of the Silver Age K.D. Balmont. The cultural significance of K.D. Balmont's work is undoubtedly for the ideas of the Silver Age. The purpose of the study is to analyze the work of K.D. Balmont and identify oriental images and motifs such as: the Enlightened Buddha, the desert, the Sphinx, the Koran, Allah, the Merciful. The object and material of the study were the poetic texts of K. Balmont: "Boro-Budur" from the collection "Burning Buildings", "Sphinx" from the collection "Silence", "Merciful" from the collection "Pearl Rug". The scientific novelty of our research lies in the consideration of motives and images as an important component of the figurative picture of the world and the poetic worldview of K.D. Balmont. The culturological aspect of oriental themes in the poet's work has been identified and substantiated. Such oriental ideas and motifs were formed, new images in his work as: the enlightened Buddha, Nirvana, pyramids, desert, Sphinx, motifs of the Koran, Allah, the Merciful, etc. In 1909-1912, K.D. Balmont traveled around the world. Egypt, Indonesia, and India completely conquered the poet. Balmont studied a huge number of scientific works on religion, philosophy and mythology of the East. K.D. Balmont wrote many letters, poems, travelogues, essays on the culture of the East. The poet's translation activity occupies a special niche in his work. He translated Ashwagosh's "The Life of the Buddha" from Sanskrit, Kalidasa's drama "Sakuntala", "Malyavika and Agnimitra" and "Urvashi Obtained by Courage", and he translated "The Koran" from Arabic. Folklore and mythology of India, China, Japan, and Iran are collected in the collection "Calls of Antiquity".
Verification of the γ-Reθt Transition Model in OVERFLOW and FUN3D
Authors: Shankar Venkatachari Balaji , Mysore Preethi V. , Hildebrand Nathaniel , Choudhari Meelan M. , Denison Marie F.
Published: December 2023

The findings of the recent AIAA and NATO workshops on transition modeling have underscored the importance of verifying the transition models that are based on Reynolds-averaged Navier–Stokes. To that end, the present work aims to verify the Langtry–Menter (LM2009) transition model coupled with Menter’s shear-stress transport (SST) turbulence model. Specifically, the SST-2003-LM2009 model, as implemented in the OVERFLOW structured overset solver and the FUN3D unstructured solver, is applied to both natural and bypass transition scenarios on a flat plate and to natural and separation-bubble-induced transition on the NLF-0416 airfoil. The Richardson extrapolation method was used to analyze and report the grid convergence of integrated and local load coefficients upstream, within, and downstream of the transition region, based on solutions obtained using the two solvers on identical grids. Reasonable agreement is obtained between the two codes for both global and local surface load coefficients when further refining the workshop mesh series, although with a grid-convergence index for the local friction coefficient that may exceed 1% in certain cases. The study also highlights the solution sensitivity to the choice of turbulence inflow boundary conditions and model options, along with the necessity to unambiguously specify this information for benchmark exercises.
Peripheral verbs in the meaning of movement in the Khakass language: semantics and functioning
Authors:   Research Institute of Humanities and Sayano-Altay Turkology of the Katanov Khakass State University, Abakan, Russian Federation, Chertykova M.D.
Published: December 2023

The article analyses the functionality and semantics of the Khakass expressive verbs being on the periphery of the lexico-semantic group of movement. These verbs are common for native speakers’ everyday speech and acquire the meaning of movement when used in a particular context. Their semantics is complex, with emotional, evaluative and figurative elements intersecting and overlapping with each other. The meaning of movement can be acquired in different ways. Firstly, verbs with the meaning of behavior can combine with verbs of movement. Secondly, polysemous verbs can be combined with dependent lexemes of locative semantics. Lastly, onomatopoeic verbs in secondary lexical and semantic versions can be formed by adding the forced voice affix -t-. All these functionalsemantic and grammatical properties contribute to the transition to the category of expressives denoting the subject’s figurative movement. Almost all verbs expressing the subject’s movement in their secondary lexical and semantic versions originate from verbs with neutral semantics. The expressiveness in certain word-formation and combinational models is lexically motivated, with a significant focus on imagery. Despite being frequently used, many of these verbs are missing in lexicographical sources, and for those that are listed, no information on their seme of “movement” is provided. The situation is complicated by contextual ambiguity of expressive words. Given that the abundance of expressive vocabulary in everyday conversation indicates a reliable native language proficiency and guarantees the preservation and development of the Khakass language, further lexicographic projects should take into account all the semantic and expressive nuances.
INVESTIGATION OF NMDA AND AMPA RECEPTOR GENE EXPRESSION IN THE DORSAL HIPPOCAMPUS OF RATS OF DIFFERENT AGE GROUPS IN A DEPRESSIVE-LIKE CONDITION
Authors:   Sechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint Petersburg, Prokopenko E.S. , Nadei O.V. , Agalakova N.I. ,   Saint Petersburg State Institute of Technology (Technical University)
Published: December 2023

The work presents a comparative analysis of the expression levels of genes encoding different subunits of AMPA and NMDA receptors in the dorsal hippocampus of rats at different ages in a depressive-like condition (DLC). In experimental groups of rats, changes in expression levels of the genes of these receptors subunits were detected, indicating different mechanisms of DLC development at different ages.
IDENTIFICATION OF POTENTIAL CORE GENES INVOLVED IN MALIGNANT TRANSFORMATION OF INFLAMED COLON TISSUE IN IN VIVO MURINE MODELS OF DSS-INDUCED ACUTE COLITIS AND COLITIS ASSOCIATED CANCER
Authors:   Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Savin I.A. , Markov A.V. , Zenkova M.A. , Sen’kova A.V.
Published: December 2023

In this study we report a bioinformatics analysis of transcriptomic datasets from mice with acute colitis and colitis-associated cancer and subsequent validation in in vivo models of dextran sulfate sodium (DSS)-induced colitis and colitis-associated cancer. As a result, a set of key genes playing a core function in malignant transformation of colon tissue during inflammation was revealed.
СIRCULATING DNA-MARKERS FOR PROGNOSIS AND PREDICTION OF ANTITUMOR THERAPY IN COLORECTAL CANCER
Authors:   Siberian State Medical University, Tomsk, Solovyova A.I. , Ponomaryova A.A. , Rykova E.Yu. , Tarasova A.S. , Kostromitsky D.N. , Dobrodeev A.Yu. , Afanasiev S.A. , Cherdyntseva N.V. ,   Cancer Research Institute, Tomsk National Research Medical Center RAS,   Institute of Cytology and Genetics SB RAS, Novosibirsk,   Department of Engineering Problems of Ecology, Novosibirsk State Technical University,   Tomsk State University
Published: December 2023

Colorectal cancer (CRC) is one of the frequent malignant diseases worldwide. The analysis of epigenetic factors contributed to the CRC development is needed for improvement of diagnostic and therapeutic strategies. “Liquid biopsy” seems to be an adequate approach to detect changes associated with cancer. This study devoted to investigation of methylation of LINE-1 retroelements and SEPTIN9, IKZF1 genes in blood cirDNA from CRC patients before and after treatment.
METHOD OF RAMAN SPECTROSCOPY IN MINIMALLY INVASIVE DIAGNOSTICS OF GLIOMAS OF VARIOUS GRADES OF MALIGNANCY USING MACHINE LEARNING TECHNOLOGIES
Authors:   Novosibirsk Scientific Research Institute of Traumatology and Orthopedics named after Y.L. Tsivyan, Stupak E.V. , Stupak V.V. , Glotov V.M. , Knyazkova A.I. , Samarinova A.A. , Vrazhnov D.A. , Cherkasova O.P. ,   Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University,   Faculty of Automation and Computer Engineering, Novosibirsk State Technical University,   Institute of Laser Physics SB RAS, Novosibirsk
Published: December 2023

Gliomas are one of the most frequently reported malignant tumors of the CNS. Currently, there are no methods for diagnosing brain tumors, such as determining blood plasma markers. In our study, Raman spectroscopy of blood plasma in combination with machine learning technologies makes it possible to differentiate patients with brain gliomas from patients without oncological pathology, this method can be used for minimally invasive diagnosis and determination of the degree of malignancy of brain gliomas.
OPTIMIZATION OF DNA-NANOMACHINE DESIGN FOR 16S RRNA S.AUREUS DETECTION
Authors:   SCAMT Institute, ITMO University, Saint Petersburg, Filatov P.V. , Gorbenko D.A. , Berezovskaya M.Yu. ,   PhysNano, ITMO University, Saint Petersburg
Published: December 2023

S. aureus is one of the major causative agents of nosocomial infections with a negative impact on global health. Chemiluminescent peroxidase-like DNA-nanomachine integrated into an optical detection system is a promising approach for a rapid, sensitive and selective method of pathogen detection. This work aims to develop an optimal detection strategy for 16S rRNA of S.aureus.
INDUCTION OF ANTIGEN-SPECIFIC IMMUNOLOGICAL TOLERANCE BY REGULATORY T-CELLS IN COLLAGEN-INDUCED ARTHRITIS AND TRANSPLANTATION, IN VITRO
Authors:   Scientific Institution Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Fisher M.S. , Bulygin A.S. , Kurilin V.V. , Khantakova Yu.N. , Sennikov S.V.
Published: December 2023

Induction of antigen-specific immunological tolerance with CD25 high FoxP3 hi T-regulatory cells (T-reg), plays an important role in organ transplant rejection, graft-versus-host disease, and autoimmune diseases, and helps to reduce the severity and incidence of adverse reactions associated with systemic immunosuppression in the use of traditional therapy
KINETIC PARAMETERS DETERMINATION OF THE INTERACTIONS BETWEEN CYSTEINE CATHEPSINS AND PEPTIDE INHIBITORS
Authors:   Institute of Translational Medicine and Biotechnology, Biomedical Science & Technology Park, Sechenov University, Moscow, Chepikova O.E. , Petushkova A.I. ,   Sirius University of Science and Technology, Sochi,   Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University,   Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Rodionov I.V. , Gorokhovets N.V. , Zamyatnin Jr A.A. , Savvateeva L.V.
Published: December 2023

Excess of cysteine cathepsins activity in tumor microenvironment is caused by violation of their regulation mechanisms. Proteolytic enzymes can hydrolyze endogenous cathepsin inhibitors cystatins. In this study, the interactions between exogenous covalent or non-covalent peptide inhibitors with antitumor activity and recombinant human cysteine cathepsins S and L were studied.
COMBINATIONS OF SNPS TNFRSF11B AND TNFA GENOTYPES IN PATIENTS WITH RHEUMATOID ARTHRITIS OF THE BASHKIR POPULATION IN CHELYABINSK REGION
Authors:   Chelyabinsk State University, Chumacheva Yu.V. , Stashkevich D.S.
Published: December 2023

Cytokine genes influence the nature of the immune response in rheumatoid arthritis (RA) through the level of production of encoded proteins, which makes the functional polymorphism of cytokine genes particularly interesting for research in RA. In our study, we evaluated combinations of frequencies of combinations genotype of polymorphisms of TNFRSF11B genes at point G1181C and TNFA at points G-308A, G-238A in population of Bashkir RA patients and a control group to identify possible associations.
DEVELOPMENT OF NEUTRALIZING RECOMBINANT NANOBODIES FOR TREATMENT AND PREVENTION OF COVID-19
Authors:   Scientific Research Institute for Systems Biology and Medicine, Moscow, Shokina V.A. , Doronin S.A. , Kudryavtsev A.V.
Published: December 2023

The rapid variability of coronavirus forces the use of alternative strategies to protect humans from COVID-19. Therefore, we have developed a nanobody that blocks the binding of RBD domain of the S-protein of SARS-CoV-2 virus to the angiotensin-converting enzyme type 2 (ACE2).
Ensino no suporte avançado de vida para estudantes e profissionais de enfermagem
Authors: Camboim Bianca Blois Pinheiro , Ferreira Ilma Pastana , Oliveira Vera Lucia Gomes de , Silva Elen Luce Marcal Elmescany da , Silva Carla Cristina Lucas Souza da , Cunha Katiane da Costa , Teixeira Renato da Costa , Wanzeler Everton Luis Freitas , Palácios Vera Regina da Cunha Menezes , Silva Pâmela Oliveira da
Published: December 2023

Objetivo: Identificar evidências na literatura sobre o ensino do Suporte Avançado de Vida para os estudantes e profissionais de Enfermagem. Métodos: Trata-se de uma Revisão Integrativa da Literatura (RIL). A busca foi realizada em janeiro a junho de 2023, com a utilização da estratégia PICo. A coleta dos dados ocorreu com o cruzamento dos descritores com os operadores booleanos AND e OR. Analisou-se os dados com método de Bardin. Resultados: A busca na literatura resultou em um total de 1066 publicações, após a seleção de 659 artigos, apenas 49 estudos foram rastreados pelos títulos, resumos e metodologias, em seguida com uma leitura na integra, foram incluídos 12 artigos para a produção da RIL. Conclusão: Por meio da análise dos resultados foi possível constatar que ainda existem lacunas no compartilhamento de conhecimento sobre o protocolo em Suporte Avançado de Vida para discentes e profissionais de enfermagem, ou seja, ainda há pouca divulgação de abordagens em faculdades e universidades, permitindo sinalizar falhas na formação profissional.
Updates in molecules associated with pathogenesis of amoebiasis: A mini review
Authors: Sharma Devyani , Kaur Upninder , Sehgal Rakesh
Published: December 2023

Amoebiasis caused due to the protozoan parasite Entamoeba histolytica has been ranked as the third major reason of mortality after Malaria and Schistosomiasis. The pathogen adversely impacts the health of the children and hinders their development and can lead to intestinal and extra-intestinal manifestation, leading to more than 100,000 deaths annually. The most common route of transmission is via faecal oral route, but recent reports also suggest sexual transmission among homosexual men. Recent experiments in in-vitro, in-vivo and in-silico studies have contributed to a better understanding of pathogenesis by filling in the knowledge gaps related to adhesion, invasion, phagocytosis, encystation, trogocytosis and many other processes. Experimental studies evaluating the pathogenic potential of Entamoeba dispar also highlights the importance of considering other species under this genus. Despite the recent advances, there is a need for new drug targets due to the lack of a successful vaccine yet. This review therefore summarizes the recent molecules that have been identified and assessed to play a role in various pathogenic mechanisms of the parasite, further contributing to the progression of the disease.
A rare case report of tyrosinemia type I
Authors: Matpathi Aparna
Published: December 2023

Tyrosinemia type I is a rare genetic disorder that occurs due to the deficiency of enzyme Fumarylacetoacetate hydrolase, resulting in elevated levels of tyrosine in the bloodstream. This case study focuses on a 4-year-old boy with a previous medical history of tyrosinemia type I, who has been admitted to the hospital multiple times due to this condition. The objective of presenting this case is to bring awareness regarding the challenges encountered while managing tyrosinemia, specifically medication adherence and dietary restrictions, which play a crucial role. This case report intends to provide education to medical professionals, healthcare advisors, family members, and caregivers about the rare and severe nature of tyrosinemia type I, while emphasising the importance of implementing an appropriate treatment strategy along with dietary modifications.
The trend and evolution of training in volleyball: A bibliometric analysis of the last five years
Authors: Saharullah  , Siregar Faris Zhafran , Nur Abidah , Hermawan Iwan , Medeiros Alexandre Igor Araripe
Published: December 2023

Background Problems: The main focus on improving the performance of volleyball players and teams is through training that covers various aspects. Research Objectives: This study aims to analyse and explain trends and developments in the scientific literature regarding volleyball training over the past five years while identifying the most frequently featured training concepts, methods, and techniques in bibliometric studies in the field over the same period. Methods: Publication records between 2019 and 2023 were extracted from Scopus and the Web of Science, after which the bibliographic data set was administered using ScientoPy and VOSviewer. A term search was conducted with the keywords “training” OR “exercise” OR “practice” AND “volleyball”. Findings and Results: Results showed a total of 1.105 papers were published over the past five years, with 2022 recording the highest number of articles. The International Journal of Environmental Research and Public Health was the most prolific source, with 45 papers, and Clemente, F. M., was the most published author. The United States was the leading contributor in this research domain with 137 papers. The most frequently highlighted training concepts, methods, and techniques in this topic included vertical jumps, biomechanics, body composition, muscle strength, power, endurance training, injury prevention, agility, balance, and countermovement jumps. Conclusion: The results of this study emphasise the importance of developing training-related knowledge in volleyball. For future research contributions and recommendations, some things that can be taken into consideration are increased interdisciplinary studies, more applied research, use of technology in training, focus on health and injury prevention, comparative studies between countries, and research related to youth training in volleyball. This research provided a strong foundation for further development in understanding and optimising the training of volleyball players in the future.
Comparative assessment of methods of the operative treatment of facial nerve damage caused during cerebellopontine angle neurinoma and meningioma removals
Authors: Yeghunyan Sargis M. , Yeghunyan Mamikon A.
Published: December 2023

The aim of this research paper is to point out the preconditions for facial nerve damage during CPA tumour removals and, in such cases, the appropriate choice of reconstructive surgery.
Materials and methods. In Uzhhorod National University, during the period of 2008 to 2019, surgical treatment of 212 patients with neurinomas and meningiomas of the CPA has been carried out. We have analyzed the cases of 35 (16.5%) patients with intraoperative damage of the facial nerve.
The mentioned 35 patients underwent appropriate clinical examinations during the post-operative period, which confirmed the facial nerve damage to one degree or another according to the House-Brackmann scale. The clinical signs manifested as full eyelid contact with slight effort and slight facial asymmetry during maximal effortful laughter. Slight synkinesias were noticeable, and there were no contractures until the expression of clinical signs corresponding to grade 6 - total nerve paralysis in 5 patients.
Results. The research demonstrated that patients with neurinomas larger than 3 cm in size are 5 times more likely to undergo intraoperative damage to the facial nerve than patients with the same tumour but 3 cm or less in size and 5 times more likely than patients with meningiomas as a whole.
In the group of patients aged 20-40, there were twice as many men; in the group aged 40-50, women predominated; among patients older than 50, there were equal numbers of men and women.
Remote catamnesis was traced in 19 patients, and contact with the rest of the patients was lost due to the war. Among the interviewed patients, 58% of the anastomosis was performed in the first 3 months after the initial surgery, 21% - in 4-6 months, and 21% - in more than 12 months.
The optimal timing of reinnervation after the initial surgery is the first 6 months after tumour removal.
Сonclusions. Nerve damage is more common during the removal of neurinomas 4cm or bigger in size. Reinnervation is accomplished by anastomosing the central end of the hypoglossal or accessory nerves to the peripheral end of the facial nerve, and both procedures are equally effective. Reinnervation should be performed 2 to 3 months after confirming nerve injury, but no later than 6 months.
Denotation of the real referent of the myth: the case of the image of the Aal Luuk Mas world tree
Authors:   M. K. Ammosov North-Eastern Federal University, Marianna SATANAR
Published: December 2023

This work is devoted to the problem of integrating scientific knowledge with the use of systematic methodology in research. The relevance of addressing the problem is due to the insufficient implementation of post-non-classical approaches in modern folklore studies. The level of knowledge of human culture today is increasingly demanding the synthesis of knowledge from different disciplines to expand the boundaries of worldview. The purpose of the study is to update the conceptual foundations of systematic research of mythological texts, and then to identify the real core of the myth of the Aal Luuk Mas world tree in the light of natural science theory. The materials for the analysis are extracted from the epic texts of Olonkho, where the mythological views of the Sakha ancestors are most fully preserved. Scientific novelty is seen in the very formulation of the problem of integrating knowledge and methods in the study of images of the mythological canvas of olonkho texts. The principle of integrity serves as the leading principle in the study, and a systematic approach is implemented. Structural and semantic analysis, the method of mutual interpretation of myth and science, methods of demetaphorization, dehyperbolization of the mythological image are applied. The author clarified that the approach is based on a number of concepts of the scientific paradigm “nature-man-thinking-creation”. It is proposed to introduce into folklore research the consideration of the problems of humanitarianism and myth, and science in the context of the integral field of human culture, which is possible to provide a multidimensional result of research. As a result of the analysis, the content of the ancient image of Aal Luuk Mas appears in a new light, in the form of the most important cosmic process – the spiral dynamics of systems of celestial bodies. It is emphasized that the main cosmic function of the mythological image of the Aal Luuk Mas tree as a driving principle is to ensure the dynamics, integrity and unity of the Universe at all levels of matter (microcosm, macrocosm, and megaworld). The author concludes that the results obtained contribute to the revision and possible adoption of the scientific image of the phenomenon of “spiral motion” in the form of a projection of the “psychological universal and archetype” (S. Yu. Neklyudov) mythological representations of ancient people.
Review on the book: Kobyai folklore. Executive editor M. T. Satanar. Yakutsk, Ayar Publ., 2022, 760 p.
Authors:   Institute for Humanitarian Research and North Indigenous People Problems of Siberian Branch of the Russian Academy of Sciences, Rozalia BRAVINA
Published: December 2023

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THE EPIC HERITAGE OF THE BASHKIRS OF THE RUSSIAN FEDERATION IN THE RECORDS FROM THE MID-20th CENTURY
Authors:   Order of the Badge of Honour Institute of History, Language and Literature – Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Gulnur KHUSAINOVA
Published: December 2023

The article is devoted to the topical issue of studying archival records of epic monuments recorded outside the Republic of Bashkortostan, in particular in Orenburg, Kurgan, Chelyabinsk, Samara, and Saratov regions, some of which have been published, and variants are taken into account in the comments to the volumes. In the first monograph devoted to the Bashkir heroic epic, its author A. N. Kireev noted that expeditions to the regions of the Russian Federation listed above gave a lot of new information about the Bashkir folk epic. This article is aimed at the study of epic material recorded precisely outside the Republic of Bashkortostan. The objectives of the article are to identify texts included in the volumes of the scholarly code “Bashkir folk art” and texts that have not yet been published; possible repeated recordings; determining the area of distribution of this or that epic tale, the age and gender of the informants. To solve the tasks, a statistical method was used to characterize the repertoire; the method of comparative analysis was used as the main one, an element of structural analysis and a comparative-descriptive method was also used in the study of repeated recordings in line with experimental approaches developed by V. M. Gatsak in the field of the theory of the preservation of the epic in time. The methodological basis of the article was the works of Russian, including Bashkir, researchers-predecessors in the field of epic studies: A. N. Kireev, S. A. Galina, M. M. Sagitova, V. M. Gatsak, I. V. Pukhov, etc. The study will allow us to present the content, volume of material, distribution areas of the Bashkir epic in the regions of the Russian Federation where Bashkirs live compactly. When studying archival materials, it turned out that epic works about animals and social and everyday ones were particularly widespread there. In the future, archival texts will be published and put into active scientific circulation. It is a subject for special research, including dissertations, on various genres of folklore of the Bashkirs of the Russian Federation, both from the folkloristic and linguistic point of views (dialects are interesting, both archaisms and Russian words are used, even characters of Russian folklore are found in the texts).
NARRATIVES AND RITUALS: THE INHERITANCE CONTEXT OF DAI EPICS
Authors:   Institute of Ethnic Literature, Chinese Academy of Social Sciences (CASS), Yongxian QU
Published: December 2023

The Dai ethnic group in China boasts a rich tradition of poetry and folk narratives, often closely intertwined with folk ritual activities. Behind these folk events, there are usually the associated explanatory text. This paper is based on field research data collected from 2008 to 2016, including interviews with the local people, tracking folk events, and understanding narrative texts. Three cases were selected from the data to elaborate on the relationship between rituals and narratives. The first case is wedding, the pickled fish jars in the betrothal ceremony could be explained in the narrative poem “A-Luang Basom” and the ritual of Crossing-the-Bridge during weddings simulates the typical scene of a hero's return and marriage as portrayed in the A-Luang story. The second case is funeral, where people often transcribe and recite the scripture “Ga Po” to express gratitude for the mother's childbirth. The third case involves the dedication of narratives “Ya Huanhao” or “Bu Huanhao” in Buddhist temples, narrating the story of the struggle between the rice sprite and the Buddha. The ritual of summoning “Ya Huanhao” or “Bu Huanhao” reflects deep respect for the rice sprite. Through these analyses, it becomes evident that folk narratives serve as interpretations of folk rituals. Different rituals, in turn, provide the context for the practice and transmission of narratives. Narratives and rituals complement each other, reflecting the Dai people's profound understanding of traditional poetry.
Comparative constructions with the multifunctional lexeme ush ‘as; the same as’ as a means of forming figurativeness in Chalkan folklore
Authors:   Institute of Philology of the Siberian Branch of the Russian Academy of Sciences, Natalya FEDINA , Natalia KOSHKAREVA ,   Institute of Philology of the Siberian Branch of the Russian Academy of Sciences, Ilya PLOTNIKOV ,   Institute of Philology of the Siberian Branch of the Russian Academy of Sciences
Published: December 2023

This paper is dedicated to the comparative constructions formed by the lexeme ush in the Chalkan language. The lexeme ush is a multifunctional means that is used in different types of syntactic constructions to express similarities both between the characteristics of objects and events. The conceptual and terminological apparatus for the analysis of comparative constructions is discussed with the aim of systematizing their plane of content, as well as the principles of modeling different types of comparative constructions, taking into account all the components necessary to express the comparative relation, regardless of their explicit expression. The relevance of the study is due to the appeal to comparison as one of the nuclear means of forming figurativeness. Comparative relations are the basis of epithets, metaphors and other expressive means that are actively used in folklore and literary texts to describe characters and events. The material for this paper consists of examples collected by continuous sampling from Chalkan folklore texts. In addition, several surveys were conducted among native speakers of the Chalkan language in cases when it was necessary to clarify the specifics of the language material. The main method of analysis used is the method of modeling a sentence as a unit of language, through which the plane of content of a linguistic sign is reconstructed by restoring the components missing in the utterance as the result of reduction, but necessary for the formation of a comparative relation. The following types of comparative constructions with the word ush are identified: polypredicative constructions with verbal and nominal predicates, in which ush marks the second compare (comparative standard), as well as simple and complex sentences with predicative ush, in which it plays the role of a nominal predicate with the semantics of equivalency. The novelty of the research lies in the fact that it is the first to identify the analytical-synthetic type of polypredicative constructions with the postposition ush, in which the main predicative unit represents the first comparee, the dependent predicative unit represents the second comparee, and the lexeme ush functions as a means of expressing equivalent relations between two events. The comparative use of ush is contrasted with that of another Chalkan comparative marker shylap // shchylap // shchynap, as well as cognates of the lexeme ush in other Turkic languages of Southern Siberia, primarily the functionally similar oskhas in the Khakas language, with a number of similarities and differences having been identified.