bluuebunny/crossref_metadata_2025 huggingface dataset:
Dental Health Conditions as Medical Aspects of Disability
Authors: Akande Abigail O.
Published: December 2023

Background:Medical Aspects of Disability is a required course in bachelor’s and master’s-level degree programs in the rehabilitation field. The course objectives have sustained a long tradition in American health services, education, and research by expressly excluding topics related to dental or oral health.

Objectives:This article makes the case for the integration of dental health topics into the Med Aspects course (a) as research trends highlight direct and indirect correlations between dental health, whole health, and disability, (b) as an issue with diverging rehabilitation implications across cultures, (c) as an ethical matter for rehabilitation professionals, and (d) to address the physical and psychosocial ramifications of dental health conditions on employment.

Conclusions:Implications for practice, research, and education are provided such as practitioner continuing education on dental health implications on rehabilitation goals, future research into effective oral health literacy tools and social determinants of oral health, and suggestions for related updates to rehabilitation education curriculum.
Análisis de factores de riesgo de deserción en estudiantes de pregrado. Caso Universidad de La Salle 2010-2020
Authors: Gutiérrez Guateque Gutiérrez Guateque , Pulido Suárez María del Pilar
Published: December 2023

El objeto de esta investigación son los determinantes de la deserción estudiantil en estudiantes de pregrado, caso empírico primer curso de la Universidad de La Salle. Para este propósito se emplearon datos de tres fuentes secundarias de información para 11 970 estudiantes con cohortes de ingreso comprendidas en el periodo 2010-2020. El presente estudio es de enfoque cuantitativo, tipo no experimental y carácter analítico descriptivo. Para el análisis de los determinantes se hizo uso del Modelo Logit Jerárquico, el cual permite explicar los efectos de las variables en los distintos niveles de agregación. Los resultados permitieron concluir que los hombres tienen una mayor probabilidad de abandonar que las mujeres, y que el promedio académico, la tasa de repitencia de asignaturas y la edad son los factores asociados que mejor ayudan a explicar la deserción. Adicionalmente, existen otras variables que permiten entender el abandono universitario como el nivel socioeconómico, los apoyos financieros del Icetex, los apoyos académicos, los costos de matrícula y las situaciones de calamidad.
Laporan Kasus: Ascites Disertai Distensi Vena Abdominalis Akibat Gangguan Fungsi Hati pada Anjing
Authors: Cahyanti Putu Yunika , Widyastuti Sri Kayati , Jayanti Putu Devi , Sewoyo Palagan Senopati , Permana Rizky
Published: December 2023

Gangguan fungsi hati merupakan salah satu penyebab yang sering ditemukan pada kasus ascites. Seekor anjing ras campuran betina berumur delapan tahun, dengan bobot badan 6,25 kg mengalami distensi abdomen selama empat bulan dan kesulitan bernapas. Hasil pemeriksaan fisik menunjukkan capillary refilltime(CRT) normal, suhu tubuh 39,3°C, frekuensi napas tinggi, dan terdapat distensi vena abdominalis. Hasil pemeriksaan rontgen menunjukkan adanya akumulasi cairan pada abdomen. Pemeriksaan hematologi rutin menunjukkan penurunan hemoglobin, mean corpuscular hemoglobin concentration (MCHC), dan platelet. Pemeriksaan biokimia darah menunjukkan peningkatan alanine aminotransferase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN), dan kreatinin,serta penurunan nilai albumin serum. Pemeriksaan cairan abdomen dengan teknik abdominocentesis dan pemeriksaan X-ray diketahui bahwa cairan ascites yang diperiksa tergolong jenis ascites transudatif, yaitu tidak berwarna dan bening. Berdasarkan hasil pemeriksaanklinis dan penunjang yang dilakukan, anjingkasusdisimpulkan mengalami gangguan fungsi hatidengan prognosis dubius. Terapiyang dilakukan adalah terapi simptomatik dengan memberikan obat diuretik furosemid 3,2mg/kg BBdua kali sehari selama tujuh haridan terapi suportif dengan multivitaminsebanyak 1 tabletsehari selama tujuh hariserta penggantian pakan dengan dogfoodBolt®. Setelah satu minggu perawatan, distensi abdomen berkurang dan frekuensi napas anjing membaik.Walaupun demikian, distensi pada vena abdominalis masih terlihat.
Laporan Kasus: Koinfeksi Anaplasmosis, Erhlichiosis, dan Malasezia pada Anjing Golden Retriever
Authors: Madani Inggrid , Batan I Wayan , Widyastuti Sri Kayati
Published: December 2023

Seekor anjing ras golden retrieverberjenis kelamin jantan, berumur tiga bulan, dengan bobot badan 6 kg datang ke klinik Sunset Vet Kutadengan keluhan anjing tersebut tidak mau makan dan muntah dua kali selama di rumah.Pada pemeriksaanfisik,telinga anjing kasus terlihat kotordengan warna serumen telinga cokelat kegelapandan ditemukan caplakRhipicephalus sp.Pada pemeriksaan hematologi rutin,anjing kasus mengalami anemia hipokromik mikrositik, trombositopenia, limfositopenia, dan leukositopenia. Pada pemeriksaan sitologisampelserumen telinga ditemukan adanya infeksi Malasezia spp.dan infeksi bakteri berbentuk kokus.Untuk membantu penegakkan diagnosis,dilakukan pemeriksaan rapid test dan uji Polymerase Chain Reaction(PCR).Hasil rapid testpada darah anjingkasus terdeteksi antibodiAnaplasma sp.serta untuk mencegah adanya positif palsu dilakukan pemeriksaan berdasarkan genetik DNA melalui uji PCR,didapatkan hasil positif yang ditunjukan olehadanyagaris pita pada sumur uji Anaplasma sp.dan E.canis serta padasumur kontrol.Berdasarkan anamnesis, pemeriksaan fisik, dan pemeriksaan penunjang (laboratorium),anjing kasus didiagnosismengalami anaplasmosis, ehrlichiosis, dan malaseziosisdengan prognosis fausta.Selama 10 hari, pengobatanyang diberikan yaitu antibiotik doxycycline,obat tetes telinga,vitamin,dan zat besi penambah darah yaitu sangobiondanChinese Fu Fang Jiao. Pemberian antibiotik doxycyclinetetap dilanjutkan sampai hari ke-28 untuk mengatasi inklusiintracytoplasmic. Setelah pengobatananjing kasus secara klinis tampak sehat.
Actualization of Moderate Islam in Sufism: Philosophy, Fahruddin Faiz's View
Authors: Al-Aluf Widayatul Wilda , Zahra Alifarose Syahda , . Ubaidillah
Published: December 2023

The development of religious moderation is influenced by philosophical tasawuf, which gives a new face to science. This study aims to explain Fahruddin Faiz's preaching in the actualization of moderate Islam. The focus of this research examines how the actualization of moderate Islam in the philosophical tasawuf of Fahruddin Faiz's view uses the method of library research (library research) a qualitative with discourse analysis. The findings in this study are that prior to the existence of philosophical tasawuf, tasawuf was still pure and had not been touched by philosophical teachings. so that in the end there was philosophical tasawuf where tasawuf was also influenced by philosophy, one proof of this is the existence of moderate tasawuf. And other findings that in Fahruddin Faiz's preaching regarding moderate Islam have several characteristics, including: tawazun (proportional), tawassut (middle), i'tidal (fair), tasamuh (tolerant), and i'tishad (simple). There is a strong connection with moderate tasawuf which means inter-religious tolerance that grows through the application of these characteristics. Fahruddin Faiz likens a tolerant person to the sea, because the sea is wide open, accepting anything. The sea is a symbol of relaxation, relief, and breadth.
EU migration policy: policy of humanism vs threat to national security
Authors: Gadzhimuradova Gyulnara , Vukcevic Nemanja
Published: December 2023

Uncontrolled migration sweeping Europe is a priority of the political leadership led by a number of European states such as France, Italy, as well as their allies in the United States. The climate crisis in Europe also plays an important role here, which can be resolved, according to Germany, with the help of future “new citizens” who arrived from countries in Africa and the Middle East, exclusively with a Muslim population. What are the migration and immigrant policies in EU countries? How is the immigration policy of European countries being transformed? A detailed analysis of the current state of affairs in Europe is based on official data from the national statistical services of Germany, France, Great Britain, the Ministry of European Integration of the Republic of Serbia, the Department of Civil Liberty and Immigration of the Italian Republic, as well as international organizations - the Office of the United Nations High Commissioner for Refugees (UNHCR), the International Organization for Migration (IOM), Eurostat, World Bank. The article examines the security problem in connection with the penetration of radical Islam along with refugees. The authors reveal the consequences of the migration crisis in Europe and make an attempt to answer the question: is the reception and integration of refugees an act of humanity or a problem of national security for EU countries.
Legal status of judicial institutions in the Kuban region in the post-reform period (1869–1920): based on the law enforcement practice materials
Authors: Parshina Natalia V.
Published: December 2023

On the basis of normative legal acts and archival materials, the features of the genesis of the judicial system in the Kuban region in the post-reform period are investigated. The socio-economic reasons explaining why the Judicial Statutes of 1864 were introduced in the region under consideration somewhat later than in the central provinces of the Russian Empire are revealed. With the help of historical-legal, comparative-legal, historical-archival and statistical methods of scientific cognition, the distinctive features of the formation of the post-reform judicial system in the Kuban region are identified. In particular, it is shown that, despite the all-religious principle of the work of judicial institutions, originally provided for in the relevant legislation of 1864, the features of class justice still continued to be preserved in the Kuban. The materials of judicial practice demonstrating the real specifics of criminal and civil proceedings in the Kuban region in the second half of the 19th century are analyzed. It is concluded that the current system of judicial system and judicial proceedings in the Kuban was a compilation of state and customary legal regulation. Along with the All-Russian legislation, it was based both on the religious norms of the mountain population and on Cossack customs, which were used in resolving civil disputes in the village courts.
Counteraction to pornography traffic in Russia and China: comparative legal analysis
Authors: Voznyak Andrei M.
Published: December 2023

The importance of the research topic lies in the emerging trend of annual growth in the number of detected crimes in the sphere of illegal traffic in pornographic materials and subjects. Domestic legal mechanisms in this sphere are not effective enough, because the prevalence of illegal trafficking in pornography does not correlate with the number of persons brought to criminal liability. This thesis is confirmed by statistical materials, according to which the relative prevalence of pornographic products per capita in Russia exceeds the same indicators in the People’s Republic of China. As the tasks of comparative legal research the study of the experience of the People’s Republic of China in regulating the pornography traffic, identification of distinctive features that can be used to optimize the domestic criminal legislation. This choice is conditioned by the similarity in the issues of counteraction to pornography traffic in Russia and China, which consists in the fact that both countries rely on common international legal standards. The research is based on the provisions of Russian, Chinese and international legislation in the sphere of counteraction to pornography traffic, while the empirical basis is statistical data and Internet research. The similarities and differences in the approaches of Russian and Chinese legislators to counteracting pornography traffic are analyzed. On the basis of the analysis, the need to adjust the content of criminal legal norms taking into account the positive foreign experience is substantiated.
Cyberspace as a crime scene: current trends, features, prevention measures
Authors: Trufanova Alexandra Yu. , Sinyaeva Maria I.
Published: December 2023

The relevance of this topic is due to the fact that the development of technology, the prevalence of computer technology and the Internet among the population have led to the emergence of a global problem for society – cybercrime. The purpose of this study is to analyze crimes committed in the information and digital space in the Russian Federation and determine preventive measures for various areas of this type of crime. Today, we are not yet talking about the timely universal prevention of cybercrime by law enforcement agencies; we consider it necessary to develop legislative regulation of this area of activity and to ensure the necessary retraining of law enforcement agencies to increase knowledge in the field of prevention, prevention and detection of cybercrimes. The methodology consists of dialectical, structural, formal legal and comparative legal methods, analysis and synthesis. The history and causes of crimes in the cyberspace are analyzed, the features of cyber attacks and cybercrimes in various fields are studied, and preventive measures for the corresponding crime are proposed. It is noted that the legal mechanisms of responsibility for some types of crimes are absent in the legislation due to the constantly changing methods of committing crimes, which also make it difficult for law enforcement agencies to solve them. Their solution is seen in the comprehensive application of preventive measures, timely changes in legislation and regular retraining of law enforcement agencies.
Issues of jurisdiction of disputes for arbitration proceedings. Lithuanian Republic’s legislation analysis
Authors: Gavrilenko Vladimir A.
Published: December 2023

The issues of jurisdiction of civil legal disputes of business entities to arbitration proceedings are analyzed. The institution of commercial arbitration is understood as non-state economic justice. Particular attention is paid to the issues of jurisdiction of arbitration institutions to resolve certain types of disputes. Lithuanian Republic’s legislation and the activities of Lithuanian arbitration institutions are studied. It is argued that this state has formed a fairly developed market economy with a certain trade turnover. Accordingly, commercial arbitration is in demand as a non-state method of resolving economic disputes, both national and international, between business entities. Attention is drawn to the genesis of the legal system of Lithuanian Republic, which was influenced by both the legal system of the former USSR and the modern Russian Federation, as well as the legal systems of Western and Eastern European countries. The industry of commercial arbitration of Lithuanian Republic and the legal regulation of issues of jurisdiction of disputes and the competence of arbitration institutions are examined in detail. Conclusions are formulated on the legislative regulation of issues of jurisdiction of disputes in arbitration proceedings.
Remarks on Hansson’s model of value-dependent scientific corpus
Authors: Stamenkovic Philippe
Published: December 2023

This article discusses Hansson's corpus model for the influence of values (in particular, non-epistemic ones) in the hypothesis acceptance/rejection phase of scientific inquiry. This corpus model is based on Hansson's very convincing concepts of scientific corpus and science ‘in the large sense’. I present Hansson's corpus model of value influence, comment on its origins, analyse its advantages and disadvantages, and conclude that it is a very good candidate for managing value influence, because contrary to other models in the literature it is simple, it provides a universal procedure for dealing with values, and it systematically preserves the epistemic integrity of science. I comment on potential difficulties associated with this model: how it manages controversial non-epistemic values; the difficulties associated with systematically taking the maximum corpus entry requirement (difficulty to identify this maximum requirement, and non-optimality with respect to other less demanding requirements); and the issue whether a claim belonging to the corpus could still be deemed not reliable enough for practical applications. I note that these issues do not put into question the applicability of the corpus model, but rather underline the need of precisely defining the frontier between the corpus and its context of application. Finally, I call for empirical work (in particular, interviews of practising scientists) in order to better assess these issues.
Objectivité, vérité et évaluation des savoirs dans les recherches participatives Le cas de l’environnement
Authors: Allamel-Raffin Catherine , Ancori Bernard
Published: December 2023

Après avoir présenté une conception radicale des recherches participatives, ce texte montre que les savoirs produits dans un tel cadre sont de nature hybride et peuvent être qualifiés de transdisciplinaires, au sens fort de ce qualificatif qui souligne que ces savoirs vont au-delà de toute catégorisation de savoirs constitués. Cette transdisciplinarité forte pose la question de la vérité et de l’objectivité des énoncés ainsi produits. La réponse à cette double question conditionne à la fois l’excellence épistémique et la pertinence sociale de ces énoncés, qui ont pour vocation de déboucher sur des actions aptes à répondre aux attentes cognitives et sociales de toutes les parties prenantes. Une telle vocation implique une conduite inédite de l’évaluation des savoirs impliqués, du point de vue de leur pertinence épistémique comme de celui de leur pertinence sociale.
Globba amicitia (Zingiberaceae: Globbeae), a new species from Phou Khao Khouay National Protected Area, Bolikhamxay Province, Laos
Authors:   Biology Department, Faculty of Natural Sciences, National University of Laos, P.O. Box: 7322, Vientiane, Laos, Souvannakhoummane Keooudone , Lanorsavanh Soulivanh ,   Biology Department, Faculty of Natural Sciences, National University of Laos, P.O. Box: 7322, Vientiane, Laos, Sangvirotjanapat Sunisa ,   Project of Institute Establishment for Sireeruckhachati Nature Learning Park, Mahidol University, Nakhon Pathom 73170, Thailand
Published: December 2023

Globba amicitia (Zingiberaceae: Globbeae), a new species from Laos is described and illustrated. This species is morphologically most similar to G. larsenii, a species from Thailand, in having erect inflorescences and entirely yellow flowers without spots, but easily recognizable by its sessile cincinni and puberulent lateral staminodes. A proposed IUCN Red List assessment and notes on distinguishing characters are provided. A key to species of Globba subgenus Globba in the Indo-Chinese region is included.
Chillida en América. Un encuentro con la modernidad al otro lado del Atlántico
Authors: López-Martín Pablo
Published: December 2023

En 1958 Eduardo Chillida recibe una beca de la Fundación Graham de Chicago en la que es alentado a profundizar en los aspectos de su trabajo más cercanos a la disciplina arquitectónica. Detrás de esta beca se encontraban figuras imprescindibles para la difusión de los valores de la arquitectura moderna en América como Mies van der Rohe, Sigfreid Giedion o Josep Lluis Sert. La obra de Chillida evidencia un paso de los Ikaraundi, que comienzan en 1957, hasta las obras que se interesan decididamente por los fenómenos espaciales (los Elogios de la arquitectura o los Lugares de encuentro) a finales de los 60. Este año de beca hace de bisagra y de acercamiento al campo de la arquitectura como él mismo reconoce en el informe que redactará para la recepción de la misma. Este capítulo de su biografía ha sido hasta ahora apenas considerado para explicar este giro tan trascendental en su carrera.AbstractIn 1958 Eduardo Chillida received a scholarship from the Graham Foundation of Chicago in which he was encouraged to explore deeper into those aspects of his work that are closest to the architectural discipline. Behind this scholarship there were essential figures for the dissemination of the values of modern architecture in America such as Mies van der Rohe, Sigfreid Giedion or Josep Lluis Sert. Chillida's work shows a step from the Ikaraundi, which began in 1957, to the works that are decidedly interested in spatial phenomena (the Praise of Architecture or the Meeting Places) at the end of the 60s. This year of scholarship of hinge and approach to the field of architecture as he himself recognizes in the report that he will write for its reception. This chapter of his biography has until now barely been considered to explain this momentous turn in his career.
Bangkok: 1999- 2542. Examining the Legacy of the Sixth Edition of “Cities on the Move”
Authors: García-Moro Francisco
Published: December 2023

“Cities on the Move” was an itinerant art exhibition curated by Hans-Ulrigh Obrist and Hou Hanru that versed about modern urbanity in Asia. The sixth edition took place in 1999 in Bangkok, a city that was still recovering from a severe financial crisis. At that time, the Thai capital lacked exhibition venues fit for international shows.However, such inconvenience turned into an opportunity to display the artworks right at the urban realm for which they had been created. The event took place in a non-Western setting at the cusp of its particular stance of Postmodernity, at a time when globalization was in its nascent stages and the rise of China was a mere promise. The curatorial manifest, as well as the setup of the itinerant show, was markedly influenced by architect Rem Koolhaas and his vision about the upcoming development of Asia. To date, the Bangkok event has not received the same attention as other editions that enjoyed better support and attention by worldwide critics. Almost twenty-five years later, we examine through the lens of architecture the conditions that accompanied the Sixth Edition of “Cities on the Move”, assessing the significance of its legacy as a pivot moment in contemporary art and urban studies in Asia.
Review of the book La cultura arquitectónica en los años de la Transición
Authors: Delgado-Orusco Eduardo
Published: December 2023

Resumen
Perfil profesional y satisfacción laboral de técnicos deportivos = Profesional profile and job satisfaction of sports instructors
Authors: Aznar Ballesta Antonio , Vernetta Santana Mercedes
Published: December 2023

ResumenEl objetivo del estudio fue conocer el perfil profesional y satisfacción laboral de los técnicos deportivos que trabajan con jóvenes estudiantes de educación secundaria obligatoria y bachillerato en servicios deportivos públicos (Ayuntamiento) y privados (empresas, asociaciones y clubes) dada la importancia que tiene su repercusión respecto a la calidad del servicio. La muestra estuvo formada por 60 trabajadores entre 18 y 62 años, siendo el 76,7% hombres y el 23,3% mujeres. Se utilizó un cuestionario ad hoc para determinar su perfil y el Overall Job Satisfaction de Warr, Cook y Wall (1979), adaptado al español por Pérez Bilbao y Fidalgo Vega (1995), para conocer su grado de satisfacción. La mayoría tienen contratos de voluntariado o eventuales, con sueldos que no superan los 500 €. Seencontró una correlación significativa y negativa entre la titulación y la satisfacción extrínseca (r=-0,133). La satisfacción se encontró más alta en la dimensión intrínseca que en la extrínseca. Dentrode las subescalas, los valores más altos de satisfacción se dieron en la libertad en la forma de trabajar y los más bajos en el salario. En conclusión, los técnicos en general están satisfechos mostrando mayores niveles las mujeres que los hombres. AbstractThe objective of this study was to know the professional profile and professional satisfaction of sports instructors who work with compulsory secondary education and baccalaureate students in public (town hall) and private (companies, associations and clubs) sport services, given the importance of their impact on service quality. The sample consisted of 60 workers between 18 and 62 years old, 76,7% men and 23,3% women. An ad hoc questionnaire was used to determine their profile and the Overall Job Satisfaction of Warr, Cook and Wall (1979), adapted to Spanish by Pérez Bilbao and Fidalgo Vega (1995), to find out their degree of satisfaction. Most of them are volunteer or have eventual contracts, with salaries under 500 €. A significant and negative correlation was found between qualifications and extrinsic satisfaction (r=-0.133). Satisfaction was found to be higher in theintrinsic dimension than in the extrinsic one. Within the subscales, the highest satisfaction values were related to freedom at work, while the lowest was related to salary. In conclusion, instructors are in general satisfied, showing women higher levels than men.
Enrique Carlos Romero Brest. Entre viajes, redes y producción de saberes = Enrique Carlos Romero Brest. Between travel, networks and knowledge production
Authors: Levoratti Alejo , Scharagrodsky Pablo
Published: December 2023

ResumenEnrique Carlos Romero Brest fue desde la década de 1930 hasta 1980 un actor clave en la Educación Física. Él cumplió diversos roles en el Estado argentino, pero un lugar en el que se destacó fue en la construcción de lazos y redes transnacionales que organizó y en algunos de los casos dirigió. Desde estos espacios se pusieron en circulación varias propuestas disciplinares y se demandó a los gobiernos de la región por el estado de la disciplina. Además, escribió artículos en revistas nacionales e internacionales y dictó conferencias en diversos países. Es por ello, que este trabajo busca analizar las redes que fue construyendo y los diferentes enfoques conceptuales que promovióen sus escritos. AbstractEnrique Carlos Romero Brest was from the 1930s to the 1980s a key actor in Physical Education. He fulfilled various roles in the Argentine State, but one place where he stood out was in the construction of transnational ties and networks that he organized and in some cases led. From these spaces,several disciplinary proposals were put into circulation and the governments of the region were sued for the state of discipline. In addition, he wrote articles in national and international journals and gave conferences in various countries. That is why this work seeks to analyze the networks he was building and the different conceptual approaches he promoted in his writings.
Working Capital Optimization and Firm’s Performance: Evidence from Indian Cement Industry
Authors: Panigrahi CMA (Dr.) Ashok
Published: December 2023

Optimum usage of working capital is always considered the key to the success of an enterprise. There is much evidence in the financial literature that an efficient management of working capital has a positive impact on the performance of the organisation. Present research work is an endeavour in this direction of establishing the factual importance of efficient management of working capital to any organization, particularly to Indian cement companies. The study employs a quantitative approach to examine whether the Indian cement companies optimally use their working capital, which is analysed by establishing the relationship between the working capital management and profitability using 11-year (2010-2021) financial data of 31 cement companies listed in Bombay Stock Exchange (BSE). The findings of this study show that the inventory turnover period (ITP) and cash conversion cycle (CCC) have a negative impact on returns on assets (ROA) whereas the accounts receivable period (ARP) does not significantly predict the return on assets of cement companies. The current ratio (CR) is negatively related to ROA whereas the quick ratio (QR) favourably predicts ROA of the cement companies. It was observed that only ITP and CCC are significantly related to return on equity (ROE) where the direction of the relationship is negative, which of course contradicts the findings of some earlier studies.
Challenging Standard Protocols: A New Perspective on MMR Deficiency from a Longitudinal Regional Study
Authors: Zhang Eric Y , Yan Min , Owens Victoria LS , Xia Yan
Published: December 2023

The role of DNA mismatch repair (MMR) tumor testing in colon and endometrial carcinomas is well-established, yet the universal application of this testing faces challenges due to limited data on its efficacy in diverse populations. This retrospective study at a community hospital in Northern Indiana examined MMR immunohistochemistry (IHC) results across 549 cases. Our analysis found intact MMR expression in 469 cases, while 80 demonstrated MMR deficiency, translating to MMR deficiency rates of 10% in colon cancers and 22% in uterine carcinomas. Notably, only 16 patients (2.9%) were categorized as high microsatellite instability (MSI-H), a rate significantly lower than the 3-5-fold higher incidences reported in other Midwestern populations, including Ohio. These findings suggest that the benefits of universal cascade methylation testing, particularly in MLH1/PMS2 IHC-negative tumors, may vary significantly based on regional demographics. Given the notably lower MSI-H incidence in this study, re-evaluating reflex testing protocols in low-resource settings could lead to more targeted, cost-effective approaches without compromising diagnostic accuracy. This study challenges the one-size-fits-all approach to MMR testing, highlighting the need for tailored strategies that consider regional variations in cancer genetics.
Intestinal Intussusception in Adult Patients. A Single Center Experience and Review of the Literature
Authors: Atmatzidis Stefanos , Raptis Dimitrios N. , Stratinaki Vasiliki Elisavet , Voloudakis Nikolaos , Martzivanou Eirini , Papatzelos Athanasios , Kyriakidou Eftychia , Koutelidakis Ioannis , Chatzimavroudis Grigoris , Papaziogas Basilios
Published: December 2023

Bowel intussusception is a rare cause of acute or subacute abdomen in adults. The frequency, etiology, symptoms, diagnosis and treatment of the disease differ significantly in comparison to the pediatric population. In adult patients, the cause of the intussusception in the majority of the cases is an underlying intestinal tumor (benign or malign), leading in a complete or incomplete mechanical ileus with corresponding symptoms. Diagnosis via imaging modalities may be challenging and is sometimes set only after exploratory laparotomy. Surgical treatment in adult patients is most of the times mandatory, because it aims not only to reverse the intussusception but also to treat the underlying cause of the disease. We present 4 cases of adult intussusception that were treated surgically and discuss the crucial points in the management of this disease through a review of the literature.
Aberrant Hippocampal Neuroregenerative Plasticity in Schizophrenia: Reactive Neuroblostosis as a Possible Pathocellular Mechanism of Hallucination
Authors: Babu Deva Irakkam Mercy Priyadharshini , Joseph Jerly Helan Mary , Kandasamy Mahesh
Published: December 2023

Schizophrenia is a spectrum of neuropsychiatric deformities, characterized by hallucination, delusion, mood disorders, speech pathology, and neurocognitive deficits. Among various clinical manifestations, hallucination has been recognized as a core psychotic symptom that occurs more frequently in schizophrenia. A significant number of subjects with neurocognitive disorders like Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and other neurological diseases like stroke and epileptic seizure also experience hallucinations. While aberrant neurotransmission has been linked to the neuropathogenic events of schizophrenia, the specific cellular mechanism contributing to hallucinations remains ambiguous. Neurodegeneration in the hippocampus of the brain has been identified as a predominant pathogenic determinant of dementia. While the scientific proof for the neurodegeneration in schizophrenia is limited, the occurrence of dementia in schizophrenia has become increasingly evident. To note, both neurodegenerative, neurodevelopmental, and neuropsychiatric disorders display impaired neurogenesis in the brain. Impaired neurogenesis in the hippocampus has been linked to dementia and mood disorders. Notably, the early phase of many neurodegenerative disorders has been characterized by reactive neuroblostosis and aberrant cell cycle activation in mature neurons leading to the fluctuation in neurogenic processes leading to abnormal synaptogenesis and neurotransmission in the brain. Thus, this article emphasizes a hypothesis that aberrant neurogenic processes could be an underlying mechanism of hallucination in schizophrenia and other neurological diseases.
Research on the construction and measurement of digital governance level system of county rural areas in China-- Empirical analysis based on entropy weight Topsis model
Authors: Wang Dingliang , Wang Tieli
Published: December 2023

Abstract: Rural digital governance is an inevitable requirement to improve the efficiency of rural governance, and is also an important means to realize the modernization of rural governance. In the context of the digital rural development strategy, the index measurement system of rural digital governance level is built around five key governance areas of "digital economy, digital ecology, digital culture, digital people's livelihood, and digital government affairs". The entropy weight Topsis model is used to measure and evaluate the level of rural digital governance in 31 provinces in China in 2021. The results show that there is a large gap in the level of digital governance in China's counties and villages, and the level of each region presents a decreasing spatial distribution from "east - middle - west". In terms of digital economy, the eastern region has a high score and good development, while the central and western regions have poor development. In terms of digital ecology, only the eastern region is higher than the national average; In terms of digital culture, only the central region is higher than the national average; In terms of digital livelihood and digital government, the central and eastern regions are slightly higher than the national average; The top three provinces in overall scores are Zhejiang, Guangdong and Jiangsu.
Clinical and Radiographic Comparison of Minimally Invasive Anterior-Posterior Combined Surgery between Oblique Lateral Interbody Fusion at L5/S1 (OLIF51) versus Transforaminal Interbody Fusion (TLIF) for Adult Spinal Deformity
Authors: Kotani Yoshihisa , Ikeura Atsushi , Tanaka Takahiro , Saito Takanori
Published: December 2023

Background and Objectives: Although adult spinal deformity (ASD) surgery brought about the improvement of quality of life in patients, it accompanied with a high invasiveness of surgery and several complications. Specifically, mechanical complications of rod fracture, instrumentation failures, and pseudarthrosis are still unsolved issues. To better improve these problems, the oblique lateral interbody fusion at L5/S1 (OLIF51) was introduced since 2015 in my institution. The objective of this study was to compare the clinical and radiographic outcomes of anterior-posterior combined surgery for ASD between the use of OLIF51 versus transforaminal interbody fusion (TLIF) at L5/S1. Materials and Methods :A total of 117 ASD patients received anterior-posterior correction surgeries either use of OLIF51 (35 patients) or L5/S1 TLIF (82 patients). In both groups, L1-5 OLIF and minimally invasive posterior procedures of hybrid or circumferential MIS were employed. The sagittal and coronal spinal alignment and spino-pelvic parameters are recorded preoperatively and at follow-up. The quality of life parameters and visual analogue scale were evaluated as well as surgical complications at follow-up. Results: The average follow-up period was thirty months (13-84). The average fused segments were eight (4-12). The operation time and estimated blood loss were significantly smaller in OLIF51 that those in TLIF. The PI-LL mismatch, LLL, L5/S1 segmental lordosis, and L5 coronal tilt were significantly better in OLIF51 than TLIF. The complication rate was statistically equivalent between two groups. Conclusion: The introduction of OLIF51 for adult spine deformity surgery led to the decrease of operation time and estimated blood loss as well as the improvement of sagittal and coronal correction when compared to TLIF.
A Clustering-Based Approach to Identifying Potential Output Anomalies with Combinatorial Testing for Web Applications
Authors: Wei Karen , Lee Shin-Jie
Published: December 2023

The process of testing software is examining the artifacts and behavior of the software under test by validating and verifying it. Testing can provide valuable information about the software. Given an input to the system, there is a challenge of distinguishing correct from potentially incorrect behavior, which is the test oracle problem. Although the combinatorial testing approach can effectively reduce the number of test cases, the manual inspection of the outputs is still required. In this paper, we propose an approach to automatically classify the return pages with conducting combinatorial testing based on page similarities and hierarchical clustering, by which potential output anomalies can be identified. In the experiment, we apply our approach to a real-world e-commerce website, an anomaly can be found with the visualization of the clustering hierarchy, which suggests the potential of the applicability of the approach.
A High-Resolution Aftershock Catalog for the 2014 Ms6.5 Ludian (China) Earthquake Using Deep Learning Methods
Authors: Li Jun , Hao Ming , Cui Zijian
Published: December 2023

A high-resolution catalog for the 2014 Ms6.5 Ludian aftershocks was constructed based on the deep learning phase-picking model (CERP) and the seismic-phase association technology (PALM). A specific training strategy, which combines the advantages of the conventional short-long window average energy ratio algorithm (STA/LTA) and AI algorithm, is employed to retrain the CERP model. The P & S phases were accurately detected and picked on continuous seismic waveforms by the retained AI model. Hypoinverse and HypoDD were utilized for precise location of 3286 events. Compared to the previous results, our new catalog exhibits superior performances in terms of location accuracy and the number of aftershock events, thereby enabling a more de-tailed depiction of the deep-seated tectonic features. According to the distribution of aftershocks, it can be inferred that, (1) the seismogenic fault of Ludian earthquake is the NW-trending Baogunao-Xiaohe Fault. (2) the Ludian aftershocks interconnected the discontinuous NW-trending Baogunao-Xiaohe Fault, and intersected with the Zhaotong-Ludian Fault. (3) It suggests that the NE-trending Zhaotong-Ludian Fault may have been intersected by the NW-trending Baogunao -Xiaohe Fault, indicating that the Baogunao-Xiaohe Fault is likely a rela-tively young Neogene fault.
Extraction of Rare Earth Elements from Chloride Solutions Using Mixtures of P507 and Cyanex 272
Authors: Afonin Mikhail A. , Nechaev Andrey V. , Yakimenko Ilya A. , Belova Vera V.
Published: December 2023

In this study, the extraction of rare earth elements (REEs) from chloride solutions containing mixtures of these metals with solutions of the mixtures of P507 and Cyanex 272 (1:1) of various concentrations was experimentally studied. It was shown that the distribution coefficients of all REEs decrease with increasing concentration of these metals in the initial solution, which is associated with the loading of the organic phase. The most significant improvement in the extraction is observed for heavy group of rare earth elements. The extractability of REEs enhances with increasing atomic number of the element, as is typical for the extraction of these metals with acidic organophosphorus extractants. The data obtained show that separation factors of adjacent rare earth elements mainly decrease with increasing concentration of metals in the initial aqueous solution. Increasing the concentration of the extractant mixture does not have a significant effect on the values of the adjacent REE separation factors. Analysis of the experimental results shows that two commercial products can be obtained from a concentrate of the medium-heavy group. In the first cascade, yttrium can be separated, in the second, a concentrate of dysprosium and terbium can be obtained.
Assessing Eelgrass Wasting Disease Dynamics in California Estuaries in the Context of Climate Change
Authors: Tallam Krti
Published: December 2023

Climate change is a global phenomenon that exerts significant impacts on ecosystems. Estuaries, as critical aquatic habitats, are susceptible to these changes; however, our comprehension of their specific responses to climate change remains limited. Beyond temperature rise and alterations in precipitation patterns, climate change induces indirect effects, influencing a multitude of biotic and abiotic variables within aquatic ecosystems. In this study, we assess seagrass health as an indicator of estuary well-being in three estuaries located in northern to central California, USA. Our investigation focuses on the marine angiosperm Zostera marina (commonly known as eelgrass) and its associated parasite, Labyrinthula zosterae. Z. marina, a temperate marine plant, faces the threat of eelgrass wasting disease (EWD) caused by the protist L. zosterae. Notably, this pathogen demonstrates sensitivity to warming ocean temperatures, underscoring the imperative to comprehend its impacts on host health amidst climate change. Our study assessed EWD prevalence with relation to spatial and temporal patterns, the relationship, if any, between disease prevalence and eelgrass percent cover, the spatial patterns, if any, of eelgrass percent cover, and what climatic variables were most strongly correlated with EWD and eelgrass percent cover.
The effect of using elements of sustainable agrotechnology in spring wheat monoculture
Authors: Gałęzewski Lech , Kotwica Karol , Kubiak Waldemar
Published: December 2023

In sustainable cultivation technologies, the method of managing crop residues and the microbiological activity of the soil supported by the application of effective microorganisms are of particular importance. Therefore, a four-year two-factor experiment was carried out with spring wheat monoculture. Six ways management of organic matter before sowing and tillage (first factor) and the application of microbiological preparations (second factor) were tested - a total - 18 experimental objects. Parameterized: weed infestation, SPAD and LAI indicators, elements of the yield structure and spring wheat yield - all features were significantly determined by the tillage technology used. In most cases, the application of biopreparations does not have a significant impact on the tested features. It was found that the highest yields of spring wheat obtained in the technology: application of EM or UGmax microbiological preparations on the shredded straw of the forecrop and mixing it with the soil using a grubber immediately after harvest, sowing of the white mustard catch crop and winter plowing.
ChAT Immunoreactive Structures in the Porcine Extrahepatic Bile Ducts
Authors: Stefanov Ivaylo Stefanov
Published: December 2023

Background: In the domestic pig, neural and non-neuronal cholinergic systems in the gallbladder and extrahepatic bile ducts need a detailed morphological study to identify the type and localization of their structural components. We aimed to quantitatively analyze biliary cholinergic ganglia and nerves as well as non-neuronal cholinergic cells; Methods: Immunohistochemical detection of choline acetyltransferase expression was performed to define cholinergic nerve and non-neuronal structures in gallbladder and extrahepatic bile ducts; Results: The number and dimensions of cholinergic ganglia, perikaryons and nerves forming ganglionic nerve plexuses in the propria, muscular and subserosal layers was estimated. The immunoexpression of choline acetyltransferase in biliary glandular cells and mast cells was also detected and analyzed. Conclusions: Qualitative and quantitative analysis of choline acetyltransferase positive nerves, ganglionic and non-ganglionic nerve plexuses of acetylcholine supplemented the morphological knowledge of the cholinergic innervation of the extrahepatic biliary pathways and non-neuronal sources: glandular cholinergic cells and cholinergic-type mast cells. Original data of the number and dimensions of intramural nerves, mast cells, ganglia and ganglion perikaryons could be used as reference values in the diagnosis of neuropathological processes in biliary pathways. Clarifying the precise mechanisms of gallbladder smooth muscle contractility will contribute to the improvement of therapeutic strategies to prevent biliary stasis and biliary disorders.
Proposing a Dynamic Decision-Making Routing Method in Underwater Internet of Things
Authors: Tarif Mehran , Nouri Moghadam Babak
Published: December 2023

Oceans cover about 70% of the Earth's surface, and about 95% remain unexplored for various reasons. Underwater wireless communication has been revolutionised with the help of Internet of Things networks. Recently, applications such as collecting marine data, marine monitoring, disaster prevention, historical exploration, oil and gas exploration, shipwreck exploration, maritime security, and monitoring of aquatic species and water pollution, and several applications have become possible. However, the problem of routing, information transfer, and resource preservation in the fluid underwater environment remains unsolved. In this research, we were looking for a solution to make routing more efficient, considering the various and practical criteria for the quality of service of the underwater IoT network. One of the outstanding features of this research is the possibility of dynamically weighing the parameters involved in routing and taking optimal and distributed decisions between network components. The proposed method has achieved acceptable results in terms of quality of service compared to recent methods.
Innovative Cloud Quantification: Deep Learning Classification and Finite Element Clustering for Ground-Based All Sky Imaging
Authors: Luo Jingxuan , Pan Yubing , Su Debin , Zhong Jinhua , Wu Lingxiao , Zhao Wei , Hu Xiaoru , Qi Zhengchao , Lu Daren , Wang Yinan
Published: December 2023

Accurate cloud quantification is essential in climate change research. In this work, we construct an automated computer vision framework by synergistically incorporating deep neural networks and finite element clustering to achieve robust whole sky image-based cloud classification, adaptive segmentation, and recognition under intricate illumination dynamics. A bespoke YOLOv8 architecture attains over 95% categorical precision across four archetypal cloud varieties curated from extensive annual observations(2020) at a Tibetan highland station. Tailor-made segmentation strategies adapted to distinct cloud configurations, allied with illumination-invariant image enhancement algorithms, effectively eliminate solar interference and substantially boost quantitative performance even in illumination-adverse analysis scenarios. In comparison to traditional NRBR threshold analysis methods, the cloud quantification accuracy computed within the framework of this paper exhibits an improvement of nearly 20%. Collectively, the methodological innovations provide an advanced solution to markedly escalate cloud quantification precision levels imperative for climate change research, while offering a paradigm for cloud analytics transferable to various meteorological stations.