bluuebunny/crossref_metadata_2025 huggingface dataset:
TO STUDY DIFFERENT COMPLICATIONS IN PATIENTS WITH MALARIA
Authors: Romday Rakesh
Published: March 2020

Method: Each patient was studied in detail with relevant clinical history and examination with following various investigations like peripheral smear for malarial parasite, complete blood count, renal function test, liver function test, blood sugar level, USG abdomen, chest x-ray, urine routine and micro and some special investigations like arterial blood gas analysis, bleeding profile, G6PD activity.

Result: Out of all patients 64% (32) had hemoglobin less than 10 g/dl. Amongst all patients with malaria 18 cases of P.vivax, 8 cases of P.vivax and 6 patient mixed infection had anemia with Hb<6g/dl. In terms of percentage 57.14% of P.falciparum and 60% of P.vivax had anemia Lowest Hemoglobin was 2.1mg/dl noted with patient of mixed infection. It was managed with transfusion of packed cell volume.

Conclusion: Both species are commonly presented with symptoms of intermittent Fever, chills, Bi-frontal headache, vomiting and commonly clinical feature is splenomegaly. Severe complication like anemia, thrombocytopenia jaundice, acute renal failure and sometimes life threatening cerebral malaria are need to address promptly to avoid adverse outcome.            All severe complications can be found in bothspecies, though less common in P.vivax as compared to Plasmodium falciparum.

Keywords: Complication, Malaria, diagnosis & Clinical Presentations
CORRELATION OF GLYCATED HAEMOGLOBIN WITH SERUM IRON, FERRITIN AND TIBC IN IRON DEFICIENCY ANEMIA
Authors: Naphade Manoj , Ambad Ranjeet
Published: March 2020

Iron deficiency anemia is a common type of anemia — a condition in which blood lacks adequate healthy red blood cells. Red blood cells carry oxygen to the body's tissues. As the name implies, iron deficiency anemia is due to insufficient iron. HbA1c shows patient’s glycemic status of last 3 months. Some previous studies have been reported that iron deficiency anemia may increase the level of HbA1c.

AIM: To assess the status of HbA1c in patients of iron deficiency anemia & correlate HbA1c level with Serum Iron, Ferritin level.

MATERIALS AND METHODS: It is a cross sectional comparative study conducted in 1 yrs of duration. A total number of 60 subjects between the ages of 18 to 60 years were enrolled for the present study. Detailed medical history and relevant clinical examination data and written consent were obtained from all subjects by explaining the study procedure.

RESULTS: Haematological parameter like Hb, MCV, MCH, HCT and RDW were showed significantly difference in iron deficiency case and   control groups. Total haemoglobin, MCV, MCH, HCT were significantly reduced in IDA case group whereas there is increase RDW level in case group as compare to control (p<0.001).

CONCLUSION: There is negative correlation of HbA1c with Haemoglobin, Serum Iron and ferritin level whereas positive correlation is detected with TIBC. The correlation of HbA1c is found to be significant with serum iron and MCH.

Keywords: Hb, MCV, MCH, HCT and RDW
THE EFFECT OF BIOFEEDBACK THERAPY FOR AUTISTIC SPECTRUM DISORDER (ASD)
Authors: Abu-Baker Rasha Zaid
Published: March 2020

Biofeedback has been reported to reduce symptoms of autism spectrum disorders (ASD) in several studies. Children affected by autism spectrum disorder (ASD) often have impairment of social interaction and demonstrate difficulty with emotional communication, display of posture and facial expression, with recognized relationships between postural control mechanisms and cognitive functions. Beside standard biomedical interventions and psychopharmacological treatments, there is increasing interest in the use of alternative non-invasive treatments such as biofeedback that could potentially modulate brain activity resulting in behavioral modification.

Biofeedback therapy is a form of alternative medicine that involves measuring a patient’s quantifiable bodily functions such as sweat gland activity, skin temperature, blood pressure, heart rate and muscle tension, conveying the information to the patient in real time, this will arise the patient’s awareness and conscious control of their unconscious physiological activities. The purpose of this paper is to assess the effectiveness of biofeedback as a method of treatment of the core symptoms of ASD.

Keywords: Biofeedback, Autistic Spectrum Disorder
TO PERFORM VARIOUS ANTHROPOMETRIC MEASUREMENTS IN CLINICAL CASES OF OBESITY
Authors: Saxena Amit , Jain Atishay
Published: March 2020

Method: This Prospective cross–sectional study was carried out in the Department of Medicine; we studied 211 consecutive patients of obesity presenting in general medicine OPD and general medical wards having associated co-morbidity. All patients or their relatives provided valid informed written consent for participation.

Result: The above table shows the mean comparison of FBS, BMI, waist hip ratio, waist circumference, hip circumference, weight and age between presence and absence of CAD. The difference was found to be statistically significant for hip circumference (P < 0.05) with a larger hip circumference in CAD present patients in comparison to the CAD absent patients. While the difference in all the other parameters were found to be statistically not significant (P>0.05), showing that all the parameters were comparable.

Conclusion: Conclusion derived from the study conducted on 211 patients of diabetes mellitus type II and overweight W.C., WHR and BMI are important, simple, cost effective, anthropometric measurements. Hence we recommended that all patients of obesity visiting Medical OPD and admitted in medical wards should not only be assessed for associated co-morbidities but for time tested anthropometric measurements.

The above table shows the mean comparison of FBS, BMI, waist hip ratio, waist circumference, hip circumference, weight and age between presence and absence of CVA. Statistically significant difference was seen in the waist circumference and WHR higher in patients with CVA in comparison to patients without CVA (P < 0.05). No statistically significant difference was seen in any of the parameters (P>0.05) between absence and presence of CVA, showing that all the parameters were comparable.

Keywords: Aanthropometric, Proforma, Clinical & Obesity.
TO DETERMINE THE IMPACT OF ART ON RENAL DISEASES IN HIV PATIENTS
Authors: Jain Atishay , Saxena Amit
Published: March 2020

The study will be carried out on HIV positive patients attending ART centre, General medicine OPD, and those admitted in Medicine wards of Bundelkhand Medical College, Sagar.

In this study, among those patients with renal dysfunction, 83.3% patients were on ART since less than 3 years. 16.7% patients were started on ART 3 to 6 years back. The influence of duration of antiretroviral therapy on risk of renal dysfunction was analyzed using One way ANOVA and Tukey pair wise analysis and found to be non significant.

This study shows that there is no significant association between the regimen of HAART and the risk of renal dysfunction. This was contrary to the commonly available data47-57 which revealed that the choice of ART may have predilection for causing renal damage especially from NNRTI group like Tenofovir, which was found to cause renal toxicity. This finding needs to be reanalyzed by further continuation of the study.

Keywords: Impact, ART, Renal & HIV patient.
EVALUATION OF C-REACTIVE PROTEINS (CRP) IN THE DIAGNOSIS OF PREMATURE RUPTURE OF MEMBRANE IN PATIENTS ATTENDING IN TERTIARY CARE HOSPITAL AT MUZAFFARPUR, BIHAR
Authors: Dipak Devkant , Kumar Manoj , Sagar Satyendu , Prasad Anant
Published: March 2020

Objective:  C-Reactive Proteins (CRP) is an important marker of Sub-clinical infection in cases of Premature Rupture of Membrane (PROM).The aim of present study was the evaluation of CRP from the patients attending in our hospital with premature rupture of membrane.

Materials and Method: A total of 32 patients of Preterm, Premature rupture of membranes and 32 patients preterm with intact membranes as a control, between 28-36 weeks of gestation were included in the study.

Results: The Sensitivity and specificity of CRP determination was found to be 78.12% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 22% and specificity of 65% in detecting histological chorioamnionitis (HCA).

Conclusion: CRP estimation is a simple, reliable, quite affordable and reasonably marker for the detection of early chorioamnionitis.

Keywords: PROM, CRP, Chorioamnionitis, Sensitivity, Specificity
THE THE NEGLECTED ASSOCIATION OF LUNGS AND GLYCEMIC CONTROL.
Authors: Das Dona , Sridhar R.V. , Chandar Midun
Published: March 2020

The awareness of diabetes and its increasing complications remain hidden and often diagnosed stage at a later stage in India, especially among the rural population. Diabetes is known  to affect multiple organs  in the body but lung as a target organ has not been highlighted enough. Pulmonary Function Test is an important tool in the early diagnosis of lung involvement in diabetes, however its availability and utility among the mass population in India is not abundant.
ATYPICAL PRESENTATION OF CAPILLARY HEMANGIOMA ON THE GINGIVA- A DIAGNOSTIC CONUNDRUM
Authors: Sharma Shivani , Bhandari SK , Issar Yuvraj , Rana Praneet K
Published: March 2020

Hemangiomas and pyogenic granulomas of oral cavity are well-known benign lesions. Pyogenic granuloma is known to show a striking predilection for the gingiva and capillary haemangioma frequently occurs in the lips, cheek, and tongue. The present case report is an atypical presentation of capillary haemangioma on gingiva which is considered to be extremely rare. The clinical presentation of the lesion in our case mimicked a pyogenic granuloma however, histopathologically was diagnosed as capillary haemangioma. These lesions present as a diagnostic dilemma to the clinician and can lead to serious complications if not carefully managed.
TO STUDY THE DIFFERENT CLINICAL PRESENTATION OF MALARIA
Authors: Daseda Saurabh , Runwal Gaurav
Published: March 2020

Method: This study was done at Department Of Medicine. All patients admitted with malaria in tertiary care Centre during the study period August 2017 to July 2018 were taken for the study after considering the inclusion and exclusion criteria. Our study is a clinical, prospective, observational and open study.

Result: Fever occurred in all patients, and it was intermittent in 72.5% of the cases, continuous in 17.5% of the cases and remittent in the remaining 10%. Intermittent fever is the commonest. All 100% patients had chills and rigors. Most of the Patients (65%) had presented with acute illness of 2- 10 days duration of fever. Bifrontal dull aching to throbbing headache associated with fever was presenting clinical symptoms in 92% of patients. Most of the patients complained of generalized weakness, malaise and myalgia. Cerebral manifestation is seen in 10% of patients. Spleenomegaly was predominant in 64% of patients and 40% patient had hepatomegaly. Patient with mixed infection had more propensity to develop systemic complication.

Conclusion: Malaria is an age-old disease of mankind, caused by protozoal plasmodium and transmitted by anopheles mosquito. It is prevalent throughout most tropical countries. Both species are commonly presented with symptoms of intermittent Fever, chills, Bi-frontal headache, vomiting and commonly clinical feature is splenomegaly. Severe complication like anemia, thrombocytopenia jaundice, acute renal failure and sometimes life threatening cerebral malaria are need to address promptly to avoid adverse outcome.

Keywords: Clinical, Malaria, WHO & Presentation.
A STUDY TO ASSESS KNOWLEDGE ATTITUDE AND PRACTICES OF PHARMACOVIGILANCE AMONGST SECOND YEAR MEDICAL STUDENTS OF A TEACHING HOSPITAL IN NORTH MAHARASHTRA.
Authors: Avhad Smita , Singh Jeetendra , Mishra Sakshi
Published: March 2020

Pharmacovigilance (PV) plays a vital role in the healthcare system through assessment, monitoring and discovery of interactions amongst drugs and their effects in human. Medicines do come with their respective adverse effects.  Therefore it is imperative to do Adverse Drug Reaction (ADR) monitoring while they are being marketed. PV is a part of the second MBBS curriculum, but often given less importance by the students. If this Knowledge Attitude & Practice of PV can be made effective during the MBBS course itself, it may make the students better aware about ADR monitoring.

Aims & Objective: Our purpose was to find out the knowledge, attitude & practices amongst the second year medical students in a tertiary care hospital in North Maharashtra.

Methods: This was an observational based study which had predesigned questions. After seeking the approval from the Institutional Ethics Committee, questionnaire was given to second year students of a tertiary care hospital in north Maharashtra. MS Excel was used for data analysis.

Results:  The overall response rate was 76%. 30% answered knowledge question correctly whereas 70% answered the attitude questions correctly. Only 4 % had reported an ADR and majority felt that busy duty hours and fear of legal action was the reason for underreporting.

Conclusion: Our study revealed that in spite of PV being part of 2nd year MBBS, it still needs more emphasis and attention. The   student feedback regarding ADR after they visit wards may help in improving the general awareness.

Keywords: Pharmacovigilance, Knowledge, Attitude, ADR.
TO FIND OUT AN APPROPRIATE CUT-OFF VALUE OF HUMAN b-HCG LEVELS IN CERVICOVAGINAL SECRETIONS FOR PREDICTION OF PRETERM DELIVERY
Authors: Meena B S , Jilowa Alka , . Purva , . Anusha , . Samta , . Neelam
Published: March 2020

Background: Preterm birth is the leading cause of neonatal morbidity and mortality worldwide and account for 75% of neonatal deaths and 50% of long term morbidity, including respiratory disease and neurodevelopment impairment.

Methods: Hospital based descriptive type of Observational study conducted at Department of Obstetrics and Gynaecology. SMS Medical College and Hospital, Jaipur (Raj.)

Results: ROC curve analysis was performed to determine the optimal cut-off values of significant variables (b-hcg harmone) detected between the two groups. A 19.05 mIU/ml (Positive if greater Than or Equal To) area under the curve (AUC = 0.906) optimal cut- off value of b-hcg harmone, with a sensitivity of 86% and a specificity of 97.1%, was determined with SE 0.036. This level is good to use as a diagnostic test.

Methods:    β-HCG test is good and β-hcg has high sensitivity and specificity so can be used as a diagnostic test for preterm labor.

Keywords: β-HCG, Sensitivity, Specificity, Diagnostic.
COMPARATIVE STUDY OF PRESSURE PROFILE TEST VERSUS PALMER’S TEST IN PREDICTING CORRECT INTRA-PERITONEAL PLACEMENT OF VERESS NEEDLE PRIOR TO INSUFFLATION DURING LAPAROSCOPIC SURGERIES
Authors: . Divya , Rajput Neelam
Published: March 2020

Background: Laparoscopy is an important and common method of accessing the peritoneal cavity to perform many types of gynaecologic surgery. Clearly safety of entry is of the utmost importance and despite debate regarding the preferred method of achieving peritoneal access; there is no single technique with demonstrated superiority.

Methods: All consecutive patients who had a legitimate indication and declared fit to undergo a laparoscopic operation in the Department of Obstetrics and Gynaecology, K D Medical College, Hospital & Research Center; Mathura (UP) underwent a prospective observational study. There were no exclusion criteria.

Results- In normal weight category sensitivity, specificity, PPV, NPV, were 0.99, 1, 1and 0.75 respectively. In overweight category sensitivity and PPV were 1, and 0.97 respectively. In obese category sensitivity, PPV, were 1and 1 respectively

Conclusion: So we can see that pressure profile test shows higher sensitivity and PPV across all grades of surgeons as well as higher specificity and NPV.

Keywords: Sensitivity, specificity, overweight.
DIFFERENCES IN THE EFFECTIVENESS OF EAR MASSAGE, DEEP BREATH RELAXATION, AND GUIDE IMAGERY IN REDUCING LABOR PAIN
Authors: Hanafi Moh. , R Wiwin Renny , . Suyanta , Rajiani Ismi
Published: March 2020

Background: Labor and birth are physiological processes of women. Although it is natural for women, but in general, the process is accompanied by severe pain and sometimes even lead to life-threatening. Childbirth pain is a problem that receives proper attention from nurses. Many alternative and complementary methods besides the use of drugs, can be applied to reduce pain. The methods applied include a holistic approach to ear massage, deep breathing relaxation, and guided imagery.

Research method: This research is a quasi experiment. The research design used in this study is the "pre test and post test group design experiment" research by collecting data twice, namely before and after treatment.

Results: From the analysis results obtained p value<0.05 indicating the three variables give the effect of the difference in pain between before and after the intervention. The difference in mean between the three interventions, ear massage and guide imagery have the same effect of reducing pain scale. However, if observed from the large value, imagery guide is the most effective in reducing labour pain. This is because the guide imagery can minimise labor pain by up to 12 times, while ear massage reduces labor pain by up to 10 times and breathing relaxation in reducing labor pain by up to 8 times.

Conclusion: There is an effect of ear massage, deep breathing relaxation and guide imagery in reducing labor pain.

Keywords: ear massage, deep breathing relaxation, and guide imagery, labor pain
SERUM-CORTISOL LEVELS IN SEVERITY OF STROKE
Authors: Agarwal Akshat , Iqbaal Haroon
Published: March 2020

Introduction: Cortisol, an important hormone in the hypothalamic pituitary adrenal axis, has important effects on the metabolism of glucose, protein and lipid[i]. A stress response consists of increased levels of cortisol and catecholamines in the 1st weeks after acute stroke. The cortisol response has been observed in cerebral infarction as well as in intracerebral haemorrhage. Change in serum level of cortisol has been reported in patients with ischemic stroke and studies reported that high levels of this hormone are independently associated with increase in ischemic lesion volume. Also it has been observed that cortisol level in patients with ischemic stroke is associated with significantly increased mortality rate. Increase in the circulating levels of catecholamines was shown in insular damage in experimental stroke suggesting this as a mechanism for the cardiac complications associated with stroke.

Patients and Methods: All patients were included in the study who was admitted within 6 hours in the hospital after the episode of stroke. Scandinavian Stroke Scale (SSS)[ii] was monitored in all patients from admission. SSS was performed every 2 hours in the first 24 hours, every 4 hours in the next 48 hours and then daily up to day 7. Blood samples were obtained for routine investigation and estimation of serum cortisol. No patients had blood samples drawn for cortisol determination between 01:00 and 07:00 am.

Results: Mean age was observed in the current series was 72.8 ± 12.54 years. There were 34 (53.1%) male and 30(46.9%) female. SSS was observed to be 36 (21-47) on admission. History of hypertension, History of stroke, Diabetes mellitus and Atrial fibrillation was observed in 38(59.4%), 12(18.8%), 24(37.5%) and 11(17.2%) respectively. In univariate logistic regression analysis of the relations to 7 days of mortality, s-cortisol, SSS on admission, and pulse rate reached a significance level. Age, atrial fibrillation, blood glucose, body temperature 12 h after stroke onset, and the presence of early infarctions signs did not reach a significance level of 0.1 in univariate testing. S-cortisol level was higher in patients with insular involvement, 635 nmol/l, in comparison to patients without insular involvement, 589 nmol/l.

Conclusion: Adrenal glucocorticoid stress response in acute stroke is harmful. High cortisol levels are associated with the poor outcome and mortality of the patients with stroke.

Keywords: Cortisol, HPA, Stroke, SSS
EFFECTIVENESS OF THE ONE NURSING STUDENT ONE CLIENT ASSISTANCE IN REDUCING HIGH-RISK PREGNANCY
Authors: Setyowati Tutik , Nuryan Erni , . Suharto , Rajiani Ismi
Published: March 2020

Background: This research aimed to identify the effectiveness of One Nursing Student One Client (OSOC) Assistance in decreasing high-risk pregnancy as an effort to   accelerate the decline in maternal and infant mortality rates.Methods: The research design employed the post test-only control group design method, where the high-risk pregnant women are accompanied by one student one client. After supervision has been completed, the results were then compared with the control group that has been given high-risk leaflet prevention for pregnant women. Mann Whitney Test is used to test the difference statistically.Results: The results of high-risk statistical analysis of hypertension obtained results p = 0.000 (P <0.05), anemia p = 0.001 (P <0.05), swollen extremity p = 0.040 (P <0.05) which means there is   a very significant different average value of high-risk pregnancy between the control group and the experimental group. This indicates that OSOC counseling is effective in reducing high-risk pregnancies of positive urine protein to negative urine protein in Blora City Community Health Center compared with leaflets to control groups. Further, counseling at high risk of swollen extremity was obtained p = 0. 114 (P> 0.05) which mean there was no difference of the mean value of high pregnancy risk of swollen extremity between the control and experiment group.Conclusion: One nursing student one client assistance is effective in reducing high-risk of the third trimester pregnancy women suffering from hypertension, anemia and positive urine proteins. K

eywords: mentoring one nursing student one client, high-risk pregnancy
ROLE OF PLATELET RICH PLASMA IN TREATMENT OF CHRONIC NON-HEALING VENOUS ULCER
Authors: Dekhaiya Firdaus A. , Joshi Jignesh K. , Bamania Sarav
Published: March 2020

Introduction: Venous ulcers are wounds that are thought to occur due to improper functioning of venous valves, usually of the lower limbs. Considering that PRP is a source of growth factors, and consequently has mitogenic, angiogenic, and chemotactic properties, it represents an adjunctive treatment for recalcitrant wounds. Moreover, PRP provides the wound with adhesive proteins, such as fibrinogen, which are important in wound healing. PRP contain more amount of platelets, cytokines and growth factors which are dispersed in a very small amount of plasma which can be prepared from a sample of centrifuged autologous blood. Application of PRP has been reported to be effective in both acute as well as chronic non healing venous ulcers.

Aim and Objective: To evaluate the efficacy of autologous platelet rich plasma in the management of chronic venous ulcer. Material and Method: A Prospective study conducted on 100 patients of chronic venous ulcers admitted in Sir T. Hospital Bhavnagar from June 2018 to June 2019 after fulfilled our inclusion and exclusion criteria. PRP then injected intalesionally inside and around the periphery of the wound/ulcer. This process was done once/week for 12 weeks. At every week, the area and volume of ulcer was calculated and photographs were taken.

Result: All the patients showed healing of the ulcer with reduction in size of ulcer more than 90% was observed in 72 patients, followed by 80–90% reduction in wound size in 18 patients after the 12 weeks follow-up. Overall, significant reduction in size of ulcer was observed in all the treated patients.

Conclusion: Autologous platelet rich plasma (PRP) as an autologous method, it is biocompatible, simple, safe, affordable and less expensive procedure in the treatment of chronic venous ulcers. PRP is found to be useful in improving and enhancing the healing process in chronic venous leg ulcers without any side effect.

Keywords:  Venous ulcer, Platelet rich plasma
MICROBIOLOGICAL ASPECT OF FUNGAL RHINOSINUSITIS: STUDY CONDUCTED IN TERTIARY CARE HOSPITAL OF NORTH INDIA.
Authors: Kaur Shubhdeep
Published: March 2020

Introduction: Fungal rhinosinusitis is the emerging disease of current era, so isolation of fungus is important aspect to plan the treatment modalities accordingly.

Methods: 50 samples of suspected patients of fungal rhinosinusitis were studied. Various samples like nasal secretion, nasal lavage and tissue were examined on direct microscopy using KOH and processed by standard protocols for fungal culture.

Result: Out of 50 suspected cases fungal rhinosinusitis was seen in 23 (46%) cases. The 40% of cases were positive by direct microscopy using 20%KOH and 46% were positive by fungal culture. The most common fungal  isolates was Aspergillus flavus (65.5%) followed by  Aspergillus niger (13%).

Conclusion: Aspergillus spp. was the most common isolated species among all the cases of fungal rhinosinusitis.

Keywords: Aspergillus spp., Fungal, Rhinosinusitis.
DO WE NEED ETHICS? – II MBBS STUDENTS PERCEPTIONS IN LEARNING MEDICAL ETHICS.
Authors: A Anupriya , S Priya Banthavi , E Kamala , P Thirumalaikolundusubramanian , N Prabhusaran
Published: March 2020

Back ground: An Indian Medical Graduate is expected to have knowledge & acquire competencies during his formal medical course, but an understanding of professional values and ethical conduct is essential for fostering the development of a good doctor.The two major aspects of teaching medical ethics include explicit teaching of cognitive base and stage appropriate opportunities for experiential learning and reflection throughout the curriculum.

Material and Methods: It is a classroom based intervention study involving 150 second MBBS students. Self administered, semi-structured questionnaire was devised for this study. The questionnaire consisted of two parts- students perception towards learning medical ethics and their perception on statements of ethical issues which was graded on a 5 point Likert scale. An interactive lecture was done followed by which students were divided into 6 groups and case based discussions were done. Finally reflective narration was done.Statistical analysis was done by EPI Info Software. Results were expressed in mean, standard deviation and paired ‘t’ test was done.

Results: The mean pre-test & post-test score of the students towards learning medical ethics in current curriculum were 2.86 and 3.98 respectively. The mean pre-test and post-test score of students regarding statements on ethical issues were 2.82 & 3.92 respectively.

Conclusion: Medical ethics is one of the neglected topics in healthcare. To strengthen ethical reasoning and judgment in decision making, we need to expose students to various ethical scenarios based on which debates, seminars, interactive workshops can be conducted utilizing the work experience of multidisciplinary medical expertise.

Keywords:  Medical ethics, Medical practice, Students
PREVALENCE OF HYPOTHYROIDISM, DELAYED PUBERTY AND DIABETES MELLITUS IN PATIENTS OF Β-THALASSEMIA MAJOR
Authors: Manne Naresh , Gupta Bharat Kumar , Yadav Sandeep Kumar , Singhal Saurabh , Dubey Archana
Published: March 2020

Background: Beta-Thalassemia is a genetic disorder which is associated with a lot of complications. Frequent blood transfusions result in increased iron deposition in various tissues leading to dysfunction of many vital organs. Endocrine disorders constitute a major part of such complications increasing the morbidity of thalassemia manifold in the affected patients.

Methods:  This is a descriptive cross sectional study carried out in 100 diagnosed patients of beta- thalassemia major who had visited the OPD/IPD of Subharti Medical College & affiliated Hospitals, Meerut for routine blood transfusion or for any other complication. Patients were clinically examined and investigated for presence of one or more endocrine disorders on their routine appointments.

Results: Endocrine disorders were detected in a total of 82 patients. Diabetes mellitus was detected in 12% patients, hypothyroidism in 36% patients and delayed puberty was found in 72% patients. Mean serum ferritin level was found to be 5831.0±2860.5 ng/ml in beta-thalassemia Major patients, while it was in normal range in control subjects.

Conclusion: Research concluded with finding of Delayed puberty (72%), Hypothyroidism (36%) and diabetes mellitus as (12%) in beta thalassemia patients who were on regular blood transfusion therapy.  Iron overload as serum ferritin level was found to be highly raised in all study case. On the basis of our study we recommend that early detection and management protocols for these endocrinopathies may improve the life prospects of beta-thalassemia Major patients.

Keywords: Endocrine disorders, Hypothyroidism, Delayed puberty, Diabetes Mellitus Serum ferritin, Thalassemia Major.
COMPARISON OF QUANTITATIVE TUBE AGGLUTINATION AND SEMIQUANTITATIVE SLIDE AGGLUTINATION TEST FOR DIAGNOSING OF THE SUSPECTED CASES OF ENTERIC FEVER
Authors: Kaur Shubhdeep , Yadav Harsh , Singh Umed , Narain Mona , Bhardwaj Mayank , Kumar Pushpendra
Published: March 2020

Introduction: Enteric fever is the major health problem of developing country like India, with a notable morbidity and mortality. Isolation of Salmonella the causative agent from Blood is the standard laboratory method for diagnosis, but it is not available at PHC level. So, rapid and affordable diagnostic test like Widal tube and slide agglutination test are used. The present study was done to comparatively evaluate the Widal slide agglutination and tube agglutination test in detecting enteric fever.

Methods: A total of 500 patients with clinical presentation suggestive of enteric fever were included in the study whose venous blood was collected. All the samples were tested for the presence of anti O and anti H agglutinins against S. typhi and S. paratyphi A by semi quantitative slide and quantitative tube agglutination tests as per standard protocols. The titers of 1:80 (O agglutinins) and 1:160 (H agglutinins) were taken as the significant titer for the diagnosis of enteric fever.

Results: Out of 500 collected samples, 183 (36.6%) was positive by slide agglutination test, whereas, only 145 (29%) were positive by tube agglutination method. The slide test had a sensitivity of 97.2%, specificity of 88.1%, positive predictive value of 77% and negative predictive value of 98.7% as compared to Widal tube agglutination test.

Conclusions: Due to high false positivity shown by slide test, it is suggested that serological diagnosis should not be made solely on the basis of slide test rather its results should be confirmed by using Widal tube agglutination test.

Keywords: Enteric fever, Slide agglutination test, Widal tube agglutination test, Sensitivity, Specificity
TO ASSESS THE OUTCOME OF PATIENTS FOR DAY CARE SURGERY
Authors: Prashar Vishal , Singh Shamsher
Published: March 2020

Background: Day care surgery offers advantages for health care delivery system around the world and so rates have steadily increased in both developed and developing countries.

Methods: Day care surgery offers advantages for health care delivery system around the world and so rates have steadily increased in both developed and developing countries.

Results: Out of 155 patients 89 (57.4%) had an operative time of 00-30 minutes, 64 (41.3%) had an operative time of 30- 60 minutes, 2 (1.3%) had an operative time of 60-90 minutes and none took more than 90 minutes. Two Patients having an operative time period of 60-90 minutes included laparoscopic procedures converted to open cholecystectomies.

Conclusion: This study clearly shows that day care surgery is feasible and safe.

Keywords: Outcome, day care surgery, Post-operative
COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF DICLOFENAC AND ETORICOXIB ON PATIENTS WITH INFLAMED KNEE JOINT
Authors: Jha Amit Kumar , Prasad Raj Ranjan
Published: March 2020

Non steroidal anti-inflammatory drugs are non-narcotic or non opioid analgesics.Various exogenous and endogenous stimuli incite a complex reaction in vascularized connective tissue called inflammation. Preferential COX-2 inhibitors named diclofenac and Selective COX-2 inhibitor named etoricoxib was taken for my present work and anti inflammatory effect was compared with control and with each other. Student-t-test-was done to compare result. It was found that inflammation varied significantly across the three groups (P=.000) Compared to control, inflammation was less in both diclofenac and etoricoxib (P=.00). Reduction of inflammation with diclofenac was less, in comparison to etoricoxib at end. Etoricoxib is more efficacious than diclofenac.

Keywords: Etoricoxib, Diclofenac, Anti inflammatory effect.
TO STUDY THE INCIDENCE OF PRIMARY CAESAREAN SECTION IN PRIMIGRAVIDA AND MULTIGRAVIDA
Authors: Gothwal Sarika , Meena R K , Meena Rattiram
Published: March 2020

Background: Caesarean section is one of the commonly performed surgical procedures in obstetrics and is certainly one of the oldest operations in surgery. Methods-This is hospital based prospective study of comparing the primary caesarean section in primigravida and multigravida.

Results: Out of 100 primigravida patients delivered, of it(66.00%) delivered normally and 34 (34.0%) delivered by primary LSCS. Out of 100 multigravida patients delivered and out of which 75 (75.00%) delivered noramally and 22 (22.00%) were primary LSCS.

Conclusion: The rate of primary caesarean section in primigravida is higher than multigravida.

Keywords: Primigravida , Multigravida, Caesarean section.
TO STUDY AND EVALUATE THE EFFICACY OF ORAL THEOPHYLLINE IN ADDITION TO OTHER CONSERVATIVE MEASURES FOR THE TREATMENT OF PDPH.
Authors: Agrawal Sangeeta Bansal , Gupta Richa , Sharma Prerna
Published: March 2020

To provide analgesia in patients developing PDPH and to study the quality and efficacy of oral Theophylline as an addition to other conservative treatment used for PDPH.

Keywords: Efficacy, Oral, Theophylline, PDPH.
ROLE OF NANOTECHNOLOGY IN DENTAL SCIENCES: A REVIEW
Authors: N Ramakoteswara Rao , E Kranthi kiran Reddy , Gahane Leena , Ranganayakulu SV
Published: March 2020

Nano technology is the multi disciplinary science and technology, which has emerged as new science exploiting specific phenomena and direct manipulation of materials on nanoscale. Nanotechnology deals with the physical, chemical, and biological properties of structures and their parts at nanoscale dimensions. It's established on the concept by creating functional structures by controlling corpuscles and molecules on a one-by-one basis by different physical and chemical synthesis methods. Developments in materials science and, nano biotechnology is especially forestalled to provide elevates in dental sciences and initiations in oral health-related diagnostic and therapeutical methods.

Keywords: Nano Science, dentistry, Nanocomposite, Nanorobots, Nanomaterials.
DECLARATION OF EPIDEMIC PUBLIC HEALTH WITH NOVEL CORONAVIRUS
Authors: Abdulkareem Rafid A.
Published: March 2020

Coronaviruses (CoV) are broad enveloped RNA viruses in humans and animals are mostly correlated with enteric and respiratory problems. Within the last decades, incidents of high death rate triggered by the spread of CoV from animals to humans have occurred. Certain pathogen city of CoV is known species-dependent as with the extent of infection; Complications typically appear in closely associated human hosts. Epidemiologists assume that the SARS virus arose in bats (natural reservoirs hosts) that were transferred to persons in Wuhan, China. Presently, the available diagnostic tests are aimed at the traditional early detection of the causes of pneumonia, promote disease prevention efforts and collaborate with research laboratories that can conduct pan coronavirus detection or controlled sequencing. No vaccine is sufficient to protect toward coronaviruses. Also there is no clear treatment for corona virus disease. Patients take comprehensive medication in clinics and typically heal on their own after several times. A vaccine can take up to 45 months to develop. Let’s stay safe during this period of time.

Keywords: Coronaviruses, Spreading, bats, diagnostic, vaccine
EVALUATION OF QUALITY OF LIFE AND PSYCHOLOGICAL IMPLICATIONS IN PATIENTS WITH ROSACEA USING DERMATOLOGY LIFE QUALITY INDEX (DLQI) AND THE HOSPITAL ANXIETY AND DEPRESSION SCALE (HADS)
Authors: Mohta Alpana , Nyati Asha , Agrawal Aditi , Jain Suresh Kumar , Kushwaha Ramesh Kumar , Gautam Umesh , Sharma Pritee
Published: March 2020

Introduction: Rosacea is a chronic skin disease associated with high levels of psychological distress and a significant impact on quality of life.

Objective: To evaluate the quality of life, depression and anxiety in patients with rosacea.

Material and Methods- Seventy-three patients, aged 18 years or above, with a clinical diagnosis of rosacea were included in the study. All patients completed a Dermatology Life Quality Index (DLQI) questionnaire and a Hospital Anxiety and Depression Scale (HADS) quessionaire.

Results: The mean DLQI score of patients was 7.98 ± 5.86 which signified a moderate impact on quality of life. The mean HADS-A (anxiety) score was 4.83 ± 4.42, while the mean HADS-D (depression) score was 5.22 ± 4.04. Thirteen (17.81%) patients had anxiety HADS-A (≥11 points) while 11 (15.07%) patients had depression HADS-D (≥11 points). Total DLQI score of patients with rosacea correlated positively with anxiety (r = 0.67, p value- <0.001) and depression (r = 0.49, p value- <0.001)

Conclusion: Rosacea is a distressing disease which has a moderate impact on patient’s QOL. Dermatologists must always be vigilant of the psychosocial aspects of rosacea and should opt for the self-perception of rosacea by patients while prescribing a treatment regimen.

Keywords: Rosacea, dermatology life quality index, DLQI, Hospital Anxiety and Depression Scale, HADS
Food and nutrition security in Eurasia: Evolution, shocks and policies
Authors: Burkitbayeva Saule , Swinnen Johan , Warrinnier Nele
Published: March 2020

Food and nutrition security is at the forefront of policy making around the globe. This study focuses on a number of Eurasian countries, namely the Russian Federation, Kazakhstan, Uzbekistan, Armenia, Tajikistan and Kyrgyzstan. From under-nutrition to various forms of malnutrition and obesity, these countries face different challenges when it comes to food and nutrition security. Over the last three decades, their situations have been affected by a number of important income shocks, including through falling remittances from relatively wealthier to poorer countries. This paper analyzes these developments and discusses how these countries have introduced policies to address food and nutrition security.
Russian agricultural trade and world markets
Authors: Liefert William M. , Liefert Olga
Published: March 2020

Russia has moved from being a large importer of grain, soybeans, and soybean meal during the late Soviet period to a major grain exporter. The country has become the world’s top wheat exporter, supplying 20–23 percent of total world exports in 2017–2018. This article examines how Russia’s transition from a planned to a market economy that began in the early 1990s has led to substantial restructuring of its agricultural production and trade, especially in its livestock and grain sectors. The article also discusses the consequences of that restructuring for world agricultural markets, and presents outlook for Russia’s agricultural trade. Another key development is that the country’s livestock sector contracted by about half during the 1990s, a result being Russia became a big meat importer. However, since 2000 that sector has rebounded, and meat imports (especially of chicken and pork) have fallen considerably.
KAJIAN TEORITIS LAYANAN KONSELING UNTUK KORBAN KEKERASAAN DALAM RUMAH TANGGA (KDRT)
Authors: Oktasari Maria , Stevani Hayu , Solihatun Solihatun
Published: March 2020

Domestic violence is an act against someone especially women which resulted in the incidence of misery or suffering physical, psychological, sexual and/or abandonment of the household including the threat to doing the deed, coercion or deprivation of freedom are against the law in the sphere of the household (UU No. 23 Th 2004). The incidence of suffering physical, psychological, and sexual abuse on victims of domestic violence will have an impact on the lives of either not effective daily. Therefore, the impact of which must be overcome. There are several ways to help cope with the impact of, the one with the granting of domestic violence counselling services to the victims. Granting counselling service aims to help overcome the problems experienced by victims of domestic violence. How the shape of the counselling services provided for victims of domestic violence will be discussed in this paper.
EFEKTIFITAS PENYUSUNAN PROGRAM BIDANG BIMBINGAN KARIER DI SMA SE-PROVINSI BENGKULU
Authors: Aprizal Tri , Hardianti Susi
Published: March 2020

This study aims to find out: (1) a description of how the teacher guidance and counseling analyze the needs of learners to develop programs field of career counseling in high school Se Bengkulu province, (2) a description of how the teacher guidance and counseling plan organizer program fields career guidance in high school Se Bengkulu province, (3) a description of how the teacher guidance and counseling melakasanakan program field of career counseling in high school Se Bengkulu province, (4) a description of how the teacher guidance and counseling evaluate the results of exercising their program areas of career counseling in high school Se Province Bengkulu, (5) a description of how the teacher guidance and counseling melaporakan results of program implementation in the field of career counseling SMA Se Bengkulu province, (6) a description of how the follow-up guidance and counseling teachers to the field of career guidance program in SMA Se Bengkulu Province. In this study, the analysis is the Program Development Effectiveness in the field of career guidance High School Se Bengkulu Province.

The method in this study using a quantitative approach. The population in this study were 116 high school Se Bengkulu province. The sample in this study as many as 61 people. Data collection techniques in this study using a questionnaire. Data analysis techniques in the study of statistical techniques.

Once the data is collected and analyzed obtained the following results:

The level of needs analysis is carried to the preparation program of career counseling in high school field Se Bengkulu province, in keseluruahan have been effective, but there are some high school in effective gori said.

The level of planning that is carried to the preparation program of career counseling in high school field Se Bengkulu province, in keseluruahan in the category effectively.

The level of implementation of career counseling in high school field Se Bengkulu province, in keseluruahan be at an effective level, but there are some high school has enough effective, ineffective.

The level of program evaluation in the field of career counseling SMA Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has a quite effective, and ineffective.

The level of reporting program of career counseling in high school field Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has effective enough.

The level of follow-up program of career counseling in high school field Se Bengkulu province, in keseluruahan are at a level very effective, but there are some high school has effective enough.
GAMBARAN TIPE KEPRIBADIAN SISWA DI SMP NEGERI 01 KABUPATEN BENGKULU UTARA
Authors: Zumkasri Zumkasri , Hardianti Susi
Published: March 2020

This study aims to find out how the personality type description of students in State Middle School 01 North Bengkulu Regency. In this study, the analysis was focused more on sanguistic, melancholy, choleric, and pleasing personality. This type of research is quantitative descriptive research, namely research based on the philosophy of positivism, used to examine certain populations or samples, collecting data using instruments, analyzing data is quantitative. The sample of this study was 10% of the total number of students in SMP Negeri 01 Bengkulu Utara so the number of samples was 60 students. Data collection techniques in this study used a questionnaire. Data analysis techniques in this study The analysis used in this research is descriptive percentage to process data and describe data using the percentage formula.

The findings of this study are that the description of personality types of students varies, this is evidenced by the results of the percentage calculation with Sanguinis personality type by 77%, Melancholic personality type by 2%, Cholesterol personality type by 3%, and Plegmatic personality type by 18%.
PENGEMBANGAN KARAKTER CERDAS MELALUI BIMBINGAN DAN KONSELING PADA ANAK USIA DINI DI TK ISLAM SARANA BHAKTI
Authors: Evitarini Anggia
Published: March 2020

The intelligence of the nation's life is based on ability, character and character in the corridor of a dignified civilization. Thus the function of education to shape the character and civilization of the life of a dignified nation is expected to run properly. One effort to be able to build intelligent people is through the implementation of eclectic counseling, where the development of children at this age is the most important period (Golden Age) in the course of human life. Through eclectic counseling, researchers try to build intelligent characters in early childhood, especially those who are expected to support a positive personality towards the surrounding environment so that they can become future generations who are ready to build the life of the nation and state. The results showed that there was an increase in intelligent character in every early childhood in Islam Sarana Bhakti Kindergarten through the implementation of eclectic counseling.
Pemilihan Umum (Pemilu) Langsung di Indonesia Perspektif Sosiologis dan Hukum Islam
Authors: Efyanti Yasni , Zufriani Zufriani , Halim Halim
Published: March 2020

Pemilihan Umum Presiden dan Wakil Presiden merupakan suatu “ritual politik”yang secara periodik dilaksanakan di Indonesia. Berdasarkan sejarahnya, Pemilihan Umum telah dilaksanakan sebanyak 12 (dua belas kali) mulai pemilu pertama tahun 1955 hingga yang terakhir pemilu ke-12 pada tahun 2019. Pemilihan Umum di Indonesia yang menganut sistem pemilihan umum langsung sesuai yang diamanatkan UUD 1945 perubahan ketiga Pasal 22E dan sesuai dengan pasal  2 ayat (1) UUD 1945. Meskipun demikian tetap saja rakyat yang memegang kedaulatan penuh itu bervariasi jenisnya. Ada yang sadar akan demokrasi, ada yang tidak sadar demokrasi, bahkan ada yang tidak tahu akan demokrasi sama sekali. Sebagian masyarakat pun masih ada yang kurang sreg menerapkan sistem pemilu langsung tersebut. Keberatan itu disebabkan belum maju secara ekonomi, dengan tingkat pendidikan relatif rendah, apalagi sistem politiknya belum tegak di atas landasan komitmen berdemokrasi yang kuat. Bila dilihat dalam Islam, Nabi s.a.w. tidak menerima kekuasaan dari siapapun (baca: tidak mewarisi kekuasaan), kemudian Nabi s.a.w. juga tidak meninggalkan petunjuk khusus atau wasiat tentang siapa yang akan menggantikannya dalam posisi kepala Negara, sehingga ketika Nabi s.a.w. wafat yang menjadi permasalahan umat Islam adalah masalah Imamah atau kekhalifahan. Penelitian ini merupakan merupakan penelitian perpustakaan (libraryreaseach), artinya menggunakan pustaka sebagai sumber primer maupun sekunder. Sebagai sumber primer adalah kajian Islam tentang fenomena modern dandata sekunder adalah karya-karya yang berkenaan dengan fenomena perpolitikan di Indonesia. Begitu pula dalam melakukan pengumpulan data, akan dilakukan dengan menelusuri literatur-literatur dan data-data tentang pelaksanaan pemilu di Indonesia dalam 4 kali periode pemilu secara langsung. Untuk mempermudah penelitian ini akan digunakan pendekatan Historis, Deskriptif dan Komparatif. Hasil dari penelitian ini diharapkan mampu memberikan pemahaman yang kuat tentang demokrasi kepada masyarakat sehingga dapat menguatkan komitmen masyarakat dalam berdemokrasi.