bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of creative story therapy for dementia: a systematic review and meta-analysis
Authors: Ma Jinlong , Wang Qian , Lang Yanmei , Lv Shi , Xu Yuzhen , Wei Baojian
Published: September 2023

Objective

To conduct a meta-analysis of the effectiveness of creative story therapy versus routine nursing alone for the treatment of dementia.

Methods

We manually searched PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), China VIP Database (VIP), China Biomedical Literature Database (CBM), and Wanfang Data up to May 2023. Randomized controlled trials (RCTs) of creative story therapy combined with routine nursing versus routine nursing for the treatment of dementia were included.

Results

A total of 597 participants were enrolled in the 9 RCTs. Among them, 296 were in the creative story therapy group, and 301 were in the routine nursing group. We found statistically significant effects of creative story therapy combined with routine nursing on cognitive function [standardized mean difference (SMD) = 0.99, 95% CI 0.57, 1.41, P < 0.00001], CSDD score [mean difference (MD) =  − 1.71, 95% CI − 3.27, − 0.14, P < 0.00001], quality of life [SMD = 0.97, 95% CI 0.04, 1.90, P = 0.04], and social communication [MD = 0.46, 95% CI 0.17, 0.74, P < 0.00001] between the creative story therapy group and routine nursing groups; no significant difference in change in basic needs communication [MD = 0.09, 95% CI − 0.58, 0.76, P < 0.00001].

Conclusion

This meta-analysis shows that creative story therapy combined with routine nursing has significant effectiveness in improving cognitive function and depression in people with dementia. More high-quality RCTs are required to validate these results.
Food, biofuels or cosmetics? Land-use, deforestation and CO2 emissions embodied in the palm oil consumption of four European countries: a biophysical accounting approach
Authors: Bausano Giovanni , Masiero Mauro , Migliavacca Mirco , Pettenella Davide , Rougieux Paul
Published: September 2023

Around 75% of tropical deforestation in the XXI century has been driven by the expansion of agriculture and forest plantations. Since 1990s, palm oil has been standing for a critical global traded product in terms of embodied deforestation. The European Union (EU) is one of the major players in terms of embodied deforestation linked to palm oil consumption. By adopting a biophysical accounting approach, the study: (1) investigated the palm oil imports between 2000 and 2020 by four EU countries (Germany, France, Italy, and Spain) from Indonesia, Malaysia, and Papua New Guinea, (2) estimated the share of imports driven by the demand from the food, oleochemicals, and energy sectors, and (3) quantified land, deforestation, and CO2 emissions associated with Land-Use Change (LUC) embodied in trade. Different trade profiles have emerged among the four importing countries. Italy and Spain showed a major direct trade link with producing countries, while France and Germany have significant connections with non-producing countries (i.e. intermediate trade partners). Overall, our results show that, following different trends, leading consumption sectors have shifted from the food towards the energy sector. Consequently, the growing demand for palm oil as a feedstock for biofuel production has determined increased environmental impacts in South-East Asia. Since 2000, the total embodied land footprint has increased four-fold, while, over the period considered, according to our second and the third attribution approaches (i.e. historical and rapid-conversion), between 5–78 m2 of deforestation and 28–445 kg CO2 emissions associated with LUC activities have been incorporated in the per-capita consumption of palm oil and its co-products in the leading European economies. Moreover, according to the first attribution approach (i.e. concession-level) and the allocation by sector, we concluded that, between 2004 and 2016, the German food sector is the one that embodied the larger deforestation footprint, followed by the Italian and Spanish energy sectors.
Multi-level resistive switching in hafnium-oxide-based devices for neuromorphic computing
Authors: Hellenbrand Markus , MacManus-Driscoll Judith
Published: September 2023

In the growing area of neuromorphic and in-memory computing, there are multiple reviews available. Most of them cover a broad range of topics, which naturally comes at the cost of details in specific areas. Here, we address the specific area of multi-level resistive switching in hafnium-oxide-based devices for neuromorphic applications and summarize the progress of the most recent years. While the general approach of resistive switching based on hafnium oxide thin films has been very busy over the last decade or so, the development of hafnium oxide with a continuous range of programmable states per device is still at a very early stage and demonstrations are mostly at the level of individual devices with limited data provided. On the other hand, it is positive that there are a few demonstrations of full network implementations. We summarize the general status of the field, point out open questions, and provide recommendations for future work.
Machine learning emulator for physics-based prediction of ionospheric potential response to solar wind variations
Authors: Kataoka Ryuho , Nakano Shinya , Fujita Shigeru
Published: September 2023

Physics-based simulations are important for elucidating the fundamental mechanisms behind the time-varying complex ionospheric conditions, such as ionospheric potential, against unprecedented solar wind variations incident on the Earth’s magnetosphere. However, carrying out an extensive parameter survey for comprehending the nonlinear solar wind density dependence of the ionospheric potential, for example, requires state-of-the-art global magnetohydrodynamic (MHD) simulations, which cannot be executed efficiently even on large-scale cluster computers. Here, we report the performance of a machine-learning based surrogate model for estimating the ionospheric potential outputs of a global MHD simulation, using the reservoir computing technique called echo state network (ESN). The trained ESN-based emulator demonstrates exceptional speed in conducting the parameter survey, which can lead to the identification of a solar wind density dependence of the ionospheric polar cap potential. Finally, we discuss future directions including the promising application for space weather forecasting.

Graphical Abstract
Double inferior vena cava, an uncommon but relevant anatomical anomaly in surgery for lower rectal cancer: a report of two cases
Authors: Kawamura Mikio , Yamashita Shinji , Imaoka Hiroki , Shimura Tadanobu , Kitajima Takahito , Okugawa Yoshinaga , Okita Yoshiki , Ohi Masaki , Toiyama Yuji
Published: September 2023

Background

Double inferior vena cava (DIVC) is rare and usually detected incidentally. DIVC may be associated with several anatomical variants of the retroperitoneal and pelvic veins. These variants can pose a clinical problem during colorectal surgery. We present two patients with lower rectal cancer who also had a DIVC.

Case presentation

Case 1 was a 72-year-old man with advanced lower rectal cancer (T3N0M0) who underwent robot-assisted low anterior resection after neoadjuvant therapy. A DIVC was detected on preoperative computed tomography (CT). During the operation, a presacral vein was injured while mobilizing the rectum and hemostasis could not be achieved. We converted to open surgery and packed the pelvic cavity for hemostasis. Retrospective analysis suggested the injured vein arose from an interiliac vein of the presacral pelvic venous plexus. Case 2 was a 50-year-old woman with lower rectal cancer (T3N0M0), immune thrombocytopenic purpura, and a DIVC. Although preoperative three-dimensional CT angiography showed no obvious pelvic vein abnormalities, a short course of preoperative radiotherapy was delivered to avoid lateral pelvic lymph node dissection. Chemotherapy was deferred owing to her thrombocytopenic disease. Laparoscopic abdominoperineal resection was performed meticulously to minimize bleeding and achieve rapid hemostasis. No intraoperative complications occurred.

Conclusion

DIVC is often accompanied by venous malformations that may pose a problem when mobilizing the mesorectum from the retroperitoneum. Preoperative assessment of pelvic vessel anatomy using three-dimensional CT is essential in patients with a DIVC who undergo rectal surgery.
Silver nanoparticles–decorated extracellular matrix graft: fabrication and tendon reconstruction performance
Authors: Chen Sunfang , Cai Dan , Dong Qi , Ma Gaoxiang , Xu Chennan , Bao Xiaogang , Yuan Wei , Wu Bing , Fang Bin
Published: September 2023

Background

The reconstruction of tendons with large defects requires grafts with high mechanical strength and is often hindered by complications such as infection and adhesion. Hence, grafts combining the advantages of mechanical resilience and antibacterial/antiadhesion activity are highly sought after.

Methods

The silver nanoparticles (GA-Ag NPs) synthesized from gallic acid and silver nitrate were attached to a decellularized extracellular matrix (Decellularized Tendon crosslinking GA-AgNPs, DT-Ag). We examined the histological structure, mechanical property, morphology, Zeta potential, cytotoxicity, antibacterial properties, antioxidant and anti-inflammatory properties, and ability of the DT-Ag to treat tendon defects in animals.

Results

Approximately 108.57 ± 0.94 μg GA-Ag NPs loaded per 50 mg DT, the cross-linked part of GA-Ag NPs was 65.47 ± 0.57%, which provided DT-Ag with long-lasting antibacterial activity. Meanwhile, GA endowed DT-Ag with good antioxidant and anti-inflammatory activities. Additionally, The DT-Ag facilitated M2 macrophage polarization, and suppressed fibrin deposition by hindering fibroblast adhesion. Mormore, the main advantages of DT-Ag, namely its long-lasting antibacterial activity (tested using
Escherichia coli
and
Staphylococcus aureus
as models) and the ability to prevent tissue adhesion were confirmed in vivo.

Conclusion

The fabricated multifunctional tendon graft was highly hydrophilic, biocompatible, and mechanically resilient, and concluded to be well suited for dealing with the main complications of surgical tendon reconstruction and has bright application prospects.

Graphical Abstract
Short-term-outcomes of idiopathic epiretinal membranes treated with pars-plana-vitrectomy – examination of visual function and OCT-morphology
Authors: Englmaier Verena Anna , Storp Jens Julian , Eter Nicole , Al-Nawaiseh Sami
Published: September 2023

Background

Epiretinal membranes (ERM) represent one of the most common findings in retinal examination. Structural changes of the retinal layers in patients with ERM can be visualized and classified using OCT. The purpose of this study is to evaluate structural and functional changes related to surgical treatment of ERM.

Methods

Monocentric retrospective analysis of 92 patients who underwent 23-gauge-pars plana vitrectomy (ppV) combined with cataract surgery for idiopathic ERM from 2015 to 2020. Visual acuity was determined directly preoperatively, at four weeks and three months postoperatively. Disease stage and tomographic biomarkers related to ERM were assessed in OCT imaging.

Results

92 eyes of 92 patients were included. At the time of surgery, the mean patient age was 71 years. Visual acuity improved significantly by 2 lines postoperatively, on average from LogMar 0.4 to 0.2 (p < 0.001). Disease stage regressed from stage 3 to stage 2 postoperatively (p < 0.001). No patient had stage 4 postoperatively (n = 0). In the presence of preoperative intraretinal fluid, mean retinal thickness was 488 μm and decreased to 392 μm postoperatively (n = 32; p < 0.001). Preoperative presence of a Cotton Ball Sign (n = 30) was associated with better visual acuity (p = 0.009). This was also visible in patients with preoperative vitreomacular traction syndrome (p < 0.001). The presence of preoperative intraretinal fluid showed a tendency towards better disease staging after surgery (p = 0.080).

Conclusion

Surgery was able to achieve visual improvement and morphological regression of the preoperative OCT findings related to ERM. ppV led to a reduction in retinal thickness and disease stage. The presence of the Cotton Ball Sign and vitreomacular traction was associated with better visual acuity in the follow-up period. In our cohort the preoperative presence of intraretinal fluid showed a tendency for better postoperative disease staging.
Correlation of serum subfatin, cthrc1, ctrp3, ctrp6 levels with disease indices in patients with axial spondyloarthritis
Authors: Uçar İ.Merve B. , Sargin Gökhan , Tuzcu Ayça , Çildağ Songül , Şentürk Taşkın
Published: September 2023

Background

The study aimed to investigate novel biomarkers from the C1q TNF superfamily and evaluate their role in autoimmune inflammatory rheumatic diseases with the goal of identifying an effective biomarker to measure clinical disease activity and assess treatment efficacy.

Methods

Sixty-one Axial spondyloarthritis (AxSpa) patients and 30 healthy controls were enrolled in the study. The serum biomarkers subfatin, CTHRC1, CTRP3, CTRP6, IL-6, IL-17, and TNF-α and the disease indices BASDAI, BASFI, MASES, and ASDAS–ESR/CRP were evaluated and compared. The patients were then classified, and their serum biomarkers were assessed according to their ASDAS scores and their treatment regimens.

Results

Among the studied biomarkers, none showed a significant difference between the patients and the healthy controls. Although the difference was not statistically significant, the median values of serum subfatin, CTHRC1, CTRP3, CTRP6, IL-6, IL-17, and TNF-α were all found to be lower in the AxSpa patients than in the healthy controls. Furthermore, once the patients were classified regarding their disease activity, no correlation between the study biomarkers and levels of clinical disease indices was observed. Finally, biological treatments were found to affect the serum concentration of these biomarkers regardless of the level of disease activity.

Conclusion

Novel adipokines and known modulators of inflammation, circulating subfatin, CTHRC1, CTRP3, CTRP6, IL-6, IL-17, and TNF-α levels may play a role in assessing treatment efficacy, especially in those treated with TNF-inhibitors. However, we failed to demonstrate a correlation between clinical disease activity and serum biomarker levels.
Evaluation of the referral system for electrodiagnostic testing in the main Alexandria University hospital
Authors: Nassif Mohammed Elsayed , Elshatby Nehad Mohamed
Published: September 2023

Background

Nerve conduction studies and electromyography (NCS/EMG) play a key role in the evaluation of patients with neuromuscular diseases. It serves as an extension of a clinical and neurological examination. Patients should be referred to electrodiagnosis (EDX) examination with an appropriate request, including history and neurological findings. When the referring diagnosis is appropriate, the examination is quicker, less invasive and limited to the verification of the provisional diagnosis. The referral system at the hospital involves only one paper asks for (NCS/EMG) with no specific information, the electromyographer is responsible for taking the patient history and performing clinical examination. Consequently, the current referral system had many flaws that needed to be corrected to enhance it.

Aim

To evaluate the current referral system to the electrodiagnosis unit and to assess the electromyographers’ satisfaction with the new referral system.

Methods

A simple questionnaire was filled by all working electromyographers to assess their satisfaction about the referral system, then a new approved referral sheet was applied by a specialized physician to all patients attending the EDX unit for two months, then the same questionnaire to evaluate the new referral system was filled again by the same electromyographers.

Results

There was a statistically significant difference regarding the electromyographers’ satisfaction with the new referral system.

Conclusion

The electrodiagnosis examination could be easier, quicker, and more organized if preceded by a proper referral system and electrodiagnosis sheet.
Eight ‘truths’ about suicide
Authors: Gibbons Rachel
Published: September 2023

This paper summarises themes that have emerged from 14 years of study of suicide and work with those bereaved. It is based on a talk given in many clinical settings over the past 10 years. I describe my own emotional journey following impactful deaths and summarise personal ‘truths’ about suicide that have emerged over time. Case studies used for illustration are composites taken from clinical practice; accounts of relatives and other survivors of suicide; and data taken from many sources including suicide audits in mental health organisations, the police and transport services, and from the examination of coroners’ records. The intention is to assist open dialogue about the nature of suicide, to contribute to the understanding of the impact on those bereaved and to encourage open-hearted clinical engagement with those who are suicidal.
Patterns of emergency department presentations for a youth mental health cohort: data-linkage cohort study
Authors: Iorfino Frank , McHugh Catherine , Richards Matthew , Skinner Adam , Prodan Ante , Occhipinti Jo-an , Song Yun Ju Christine , Chiu Simon , Judkins Simon , Scott Elizabeth , Hickie Ian B.
Published: September 2023

Background

Primary youth mental health services in Australia have increased access to care for young people, yet the longer-term outcomes and utilisation of other health services among these populations is unclear.

Aims

To describe the emergency department presentation patterns of a help-seeking youth mental health cohort.

Method

Data linkage was performed to extract Emergency Department Data Collection registry data (i.e. emergency department presentations, pattern of re-presentations) for a transdiagnostic cohort of 7024 youths (aged 12–30 years) who presented to mental health services. Outcome measures were pattern of presentations and reason for presentations (i.e. mental illness; suicidal behaviours and self-harm; alcohol and substance use; accident and injury; physical illness; and other).

Results

During the follow-up period, 5372 (76.5%) had at least one emergency department presentation. The presentation rate was lower for males (IRR = 0.87, 95% CI 0.86–0.89) and highest among those aged 18 to 24 (IRR = 1.117, 95% CI 1.086–1.148). Almost one-third (31.12%) had an emergency department presentation that was directly associated with mental illness or substance use, and the most common reasons for presentation were for physical illness and accident or injury. Index visits for mental illness or substance use were associated with a higher rate of re-presentation.

Conclusions

Most young people presenting to primary mental health services also utilised emergency services. The preventable and repeated nature of many presentations suggests that reducing the ongoing secondary risks of mental disorders (i.e. substance misuse, suicidality, physical illness) could substantially improve the mental and physical health outcomes of young people.
Biomechanical Analysis of 2 Versus 4 Rods Across the Cervicothoracic Junction in a Human Cadaveric Model
Authors: Pivazyan Gnel , Winters Carlynn G. , Brooks Daina M. , Sandhu Faheem A. , Cunningham Bryan W.
Published: September 2023

BACKGROUND AND OBJECTIVES:

Posterior reconstruction of the cervicothoracic junction poses significant biomechanical challenges secondary to transition from the mobile cervical to rigid thoracic spines and change in alignment from lordosis to kyphosis. After destabilization, the objectives of the current investigation were to compare the rod strain and multidirectional flexibility properties of the cervicothoracic junction using a 4-rod vs traditional 2-rod reconstructions.

METHODS:

Ten human cadaveric cervicothoracic specimens underwent multidirectional flexibility testing including flexion-extension, lateral bending, and axial rotation. After intact analysis, specimens were destabilized from C4 to T3 and instrumented from C3 to T4. The following reconstructions were tested: (1) 3.5-mm titanium (Ti) 2-rod, (2) 3.5-mm Ti 4-rod, (3) 4.0-mm cobalt chrome (CoCr) 2-rod, (4) 4.0-mm CoCr 4-rod, and (5) Ti 3.5- to 5.5-mm tapered rod reconstructions. The operative level range of motion and rod strain of the primary and accessory rods were quantified.

RESULTS:

The addition of accessory rods to a traditional 2-rod construct improved the biomechanical stability of the reconstructions in all three loading modalities for Ti (P < .05). The accessory CoCr rods improved stability in flexion-extension and axial rotation (P < .05). The addition of accessory rods in Ti or CoCr reconstructions did not significantly reduce rod strain (P < .05). CoCr 2 and 4 rods exhibited less strain than both Ti 2 and 4 rods.

CONCLUSION:

Supplemental accessory rods affixed to traditional 2-rod constructs significantly improved stability of Ti alloys and CoCr alloy materials. The 4.0-mm CoCr rods provided greater stability than 3.5-mm Ti rods in flexion-extension, lateral bending, and axial rotation. While rod strain was not significantly reduced by the addition of accessory rods, it was reduced in CoCr rod treatment groups compared with the Ti rods.
Endovascular Embolization of Basilar Artery Fenestration Aneurysms: A 21-Year Institutional Case Series
Authors: Srinivasan Visish M. , Singh Rohin , Karahalios Katherine , Scherschinski Lea , Essibayi Muhammed Amir , Catapano Joshua S. , Winkler Ethan A. , Jadhav Ashutosh P. , Ducruet Andrew F. , Albuquerque Felipe C.
Published: September 2023

BACKGROUND AND OBJECTIVES:

Basilar artery fenestration is a rare phenomenon sometimes associated with basilar artery fenestration aneurysms (BAFAs). This review investigates the natural history and management outcomes of BAFAs and describes the outcomes of BAFAs treated with embolization.

METHODS:

A single-center database was queried for all cases of endovascular BAFA treatment. Data on complications, clinical and angiographic outcomes, and retreatment rates were collected.

RESULTS:

Seventeen aneurysms across 17 patients were treated. The mean (SD) age was 56 (13) years, and 15 (88%) patients were women. Among 15 aneurysms with data available, 2 arose from the fenestration limbs and 13 from both limbs and the vertebral artery. Of 16 aneurysmal projections available, 7 projected anteriorly, 7 posteriorly, and 2 superiorly. Among 17 patients, balloon-assisted coiling was the most common treatment (n = 10), followed by primary coiling (n = 3), stent-assisted coiling (n = 2), coiling with flow diversion (n = 1), and balloon-assisted coiling and flow diversion (n = 1). Complications noted in 5 patients included hemorrhage, thromboembolism, paresthesias, vasospasm, and transient hemiparesis. Among 16 patients with postoperative results available, 12 showed favorable clinical outcomes, 3 were disabled, and 1 died. The rates of postoperative complete (Raymond–Roy Occlusion Classification 1) and incomplete (Raymond–Roy Occlusion Classification 2 and 3) occlusion among 15 patients with available data were 6 and 9, respectively.

CONCLUSION:

Endovascular management of these rare aneurysms is feasible and safe, with high rates of favorable radiographic and clinical outcomes. This series reflects a general preference toward coiling and stent-assisted coiling, although flow diversion may be considered in select cases.
Anterior Cervical Discectomy and Fusion With Structural Allograft is Associated With Lower Postoperative Health Care Utilization and Reoperations Compared With Cage Implants
Authors: Powers Andrew Y. , Nin Darren Z. , Chen Ya-Wen , Niu Ruijia , Kim David H. , Chang David C. , Hwang Raymond W.
Published: September 2023

BACKGROUND AND OBJECTIVES:

Implants represent a large component of surgical cost, with several available options for anterior cervical discectomy and fusion (ACDF). Rising ACDF volume highlights the need for accurate cost characterization among implant configurations to inform efficient utilization.

METHODS:

A cohort study of patients who underwent 1-level or 2-level ACDF in 2017 was conducted using the MarketScan national insurance databases, which contain deidentified clinical and financial data. Implant configurations included plate with cage, standalone cage, and plate with structural allograft. Patients who switched insurance providers within 2 years after surgery or underwent concurrent posterior cervical surgery, cervical disk arthroplasty, or cervical corpectomy were excluded. A combined plate/cage and standalone cage group was compared with the allograft group followed by the comparison of the plate/cage and standalone cage groups. In total, 30-day, 90-day, and 2-year aggregate costs; component costs of physical therapy, injections, medications, psychological treatment, and subsequent spine surgery; and reoperation rates were evaluated.

RESULTS:

Of 1723 patients identified, 360 (20.9%) underwent surgery with plate/cage, 184 (10.7%) with standalone cage, and 1179 (68.4%) with allograft. Aggregate costs were lower in the allograft group compared with the combined cage group at 90 days ($36 428 vs $39 875, P = .04) and 2 years ($64 951 vs $74 965, P = .005) postoperatively. There were no significant differences in aggregate costs between the plate/cage and standalone cage groups. The 2-year reoperation rate was higher in the combined cage compared with the allograft group (23.9% vs 10.9%, P < .001) and was also higher in the standalone cage compared with the plate/cage group (32.0% vs 19.7%, P = .002).

CONCLUSION:

Compared with alternative ACDF constructs, allograft is associated with lower postoperative costs and reoperation rates. Although costs are similar, reoperation rates are lower with plate/cage constructs compared with those of standalone cages. Surgeons should consider these financial and clinical differences when selecting implant configurations.
Polarons, Bipolarons, and Electrical Properties of Crystalline Conducting Polymers
Authors: Furukawa Yukio , Shimokawa Daichi
Published: September 2023

In this review article, we focus on the electrical conductivity (σ), the charge number densities (n), and the carrier mobilities (μ) in crystalline conducting polymers doped by various methods, including doping with an ionic-liquid-gated transistor (ILGT) configuration and H2SO4 treatment. Electrical properties of crystalline conducting polymer poly(2,5-bis(3-alkylthiophen-2-yl)thieno[3,2-b]thiophene) (PBTTT) were investigated with a combination of ILGT configuration doping and operando Raman spectroscopy. The type of carrier, a positive polaron or a positive bipolaron, was determined with Raman spectroscopy. The values of σ and μ were determined as a function of n. The highest mobility of positive bipolarons was 1.2 cm2 V−1 s−1 at n = 6.2 × 1020 cm−3. The electrical conductivity of poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate) (PEDOT:PSS) was increased upon H2SO4 treatment. The H2SO4 treatment caused anion exchange, resulting in crystallization of the doped PEDOT. The charge density was 7.3 × 1021 cm−3. The mobility of positive bipolarons was 1.9 cm2 V−1 s−1. In heavily doped crystalline PBTTT and PEDOT, spinless positive bipolarons existed stably, and were highly mobile.
Hamstring Strain Injury Risk Factors in Australian Football Change over the Course of the Season
Authors: SIM AYLWIN , TIMMINS RYAN G. , RUDDY JOSHUA D. , SHEN HAIFENG , LIAO KEWEN , MANIAR NIRAV , HICKEY JACK T. , WILLIAMS MORGAN D. , OPAR DAVID A.
Published: September 2023

Background/aim

This study aimed to determine which factors were most predictive of hamstring strain injury (HSI) during different stages of the competition in professional Australian Football.

Methods

Across two competitive seasons, eccentric knee flexor strength and biceps femoris long head architecture of 311 Australian Football players (455 player seasons) were assessed at the start and end of preseason and in the middle of the competitive season. Details of any prospective HSI were collated by medical staff of participating teams. Multiple logistic regression models were built to identify important risk factors for HSI at the different time points across the season.

Results

There were 16, 33, and 21 new HSIs reported in preseason, early in-season, and late in-season, respectively, across two competitive seasons. Multivariate logistic regression and recursive feature selection revealed that risk factors were different for preseason, early in-season, and late in-season HSIs. A combination of previous HSI, age, height, and muscle thickness were most associated with preseason injuries (median area under the curve [AUC], 0.83). Pennation angle and fascicle length had the strongest association with early in-season injuries (median AUC, 0.86). None of the input variables were associated with late in-season injuries (median AUC, 0.46). The identification of early in-season HSI and late in-season HSI was not improved by the magnitude of change of data across preseason (median AUC, 0.67).

Conclusions

Risk factors associated with prospective HSI were different across the season in Australian Rules Football, with nonmodifiable factors (previous HSI, age, and height) mostly associated with preseason injuries. Early in-season HSI were associated with modifiable factors, notably biceps femoris long head architectural measures. The prediction of in-season HSI was not improved by assessing the magnitude of change in data across preseason.
Translation and validation of Suicide Risk Scale for Medical Inpatient (SRMI) in Urdu Language
Authors: Mehmood Mobeen , Zaman Noshi Iram
Published: September 2023

Objective: To translate and validate the suicide risk scale for medical inpatients in the Urdu language.

Methods: A correlational study with non-random sample approach was conducted from February to May 2020, data was collected from various hospitals in Rawalpindi, Islamabad, and Lahore. In the first phase, the suicide risk scale for medical inpatients was translated from the source language (English) to the target language (Urdu) via forward and backward translations. In the second phase, the Psychometric properties of the Urdu version were established. Exploratory factor analysis, reliability (Cronbach’s alpha & split-half), and validity analysis (convergent and discriminant) were also computed.

Results: A total of 200 individuals with renal failure, with a mean age of 45.33 years (range; 18-80 years) were approached for the data collection. Exploratory factor analysis computed two factors. Cronbach’s alpha value showed internal consistency and Pearson’s moment correlation indicated association among similar variables (convergent validity) and less association among dissimilar study variables (discriminant validity).

Conclusion: The Urdu version of the suicide risk scale for medical inpatients was found to be a reliable and valid instrument for assessing suicide risk in medical inpatients in Pakistani culture.

doi: https://doi.org/10.12669/pjms.39.6.7000

How to cite this: Mehmood M, Zaman NI. Translation and validation of Suicide Risk Scale for Medical Inpatient (SRMI) in Urdu Language. Pak J Med Sci. 2023;39(6):---------. doi: https://doi.org/10.12669/pjms.39.6.7000

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Translation, reliability, and validation of the Dutch Safe Use of Mobility Aid Checklist (SUMAC-NL) for walker use in people living with dementia
Authors: Kroesen Jesper , Hobbelen Hans , Hunter Susan , Bruinsma Helen , Drenth Hans
Published: September 2023

Background: People with dementia have a yearly risk of falling of 60 to 80 percent. Therefore, a walker is often recommended. However, the use of a walker in people with dementia is associated with a threefold increased odds of falls compared to their healthy peers. Better advice and training could reduce fall risk. Therefore, a tool to assess functional walking skills with a walker is needed. The SUMAC was developed to fill this gap. So far, there is no Dutch instrument available that can assess functional walking skills with a walker in people with dementia.  

Methods: Reliability was evaluated by scoring videos of people with dementia (n = 9) using a walker performing the SUMAC-NL. ICC was used to assess inter-rater and test-retest reliability. An expert panel (n = 8) evaluated the content validity using the content validity index (CVI) and the content validity ratio (CVR). 

Results: Inter-rater reliability of the SUMAC-NL was statistically significant for the PF domain (ICC = 0.94, 95%CI (0.84, 0.98, p < 0.001) and for the EQ domain (ICC = 0.79, 95%CI (0.49 – 0.95), p < 0.001). Test-retest reliability was statistically significant for both the PF domain (ICC = 0.95, 95%CI (0.89, 0.99), p < 0.001) and EQ domain (ICC = 0.92, 95%CI (0.82, 0.98), p < 0.001). The SUMAC-NL shows content validity with a CVI >0.79 for both domains and a CVR of 0.53 on the PF domain and 0.78 on the EQ domain. 

Conclusions: The SUMAC-NL shows good to excellent reliability and content validity for both the PF and the EQ domain. The SUMAC-NL seems to be a promising tool to assess walking with a walker in people with dementia in the Netherlands.
Case Report: A very rare case of a Pleural Effusion revealing Multiple Myeloma
Authors: Daboussi Selsabil , Saidane Asma , Mhamdi Samira , Kacem Marwa , Essbaa Samia , Aichaouia Chiraz , Ghedira Hela , Gargouri Faten , Msakni Issam , Moatemri Zied
Published: September 2023

Multiple myeloma is a common malignant bone-based disease. Pleural effusions reported in these patients remain rare. It is commonly due to congestive heart disease, pulmonary embolism, nephrotic syndrome or a second neoplasia. The true myelomatous pleural effusion resulting from a direct tumoral invasion of the pleural are extremely rare. We report here the case of a massive pleural effusion revealing multiple myeloma in a 71-year-old patient. The chest ultrasound showed a massive pleural effusion in the left side with a multinodular thickening of the pleura. The medical thoracoscopy showed a grape-cluster appearance. The diagnosis was made by pleural guided biopsy revealing abnormal plasma cells with an intense positive CD 138 (plasma cell marker) and MUM1 (multiple myeloma oncogene1) staining with a light kappa chain in the protein electrophoresis associated with a myeloma. Unfortunately, our patient died one month after the initial diagnosis. We present also a review of the recent literature in order to highlight the clinical presentations of the myelomatous pleural effusion, the diagnostic tools, the therapeutic strategies as well as the outcomes.
Prevalence of Frey syndrome following extraoral surgical treatment for mandibular fractures: a systematic review and meta-analysis
Authors: Kostares Evangelos , Kostares Michael , Kostare Georgia , Kantzanou Maria
Published: September 2023

Our study aims to estimate the prevalence of Frey syndrome following open reduction and internal fixation (ORIF) for mandibular fractures. Two reviewers independently conducted a systematic literature search in the Medline and Scopus databases. The pooled prevalence with 95% confidence intervals (CI) was estimated, and quality assessment, outlier analysis, and influential analysis were performed. In total, fifteen eligible studies were included in this meta-analysis. One study was identified as critically influential. The overall prevalence of Frey syndrome following extraoral surgical treatment for mandibular fractures was estimated as 0.01% (95%CI 0%-0.7%) with moderate heterogeneity observed between studies. In the meta-regression analysis with continuous variables, no statistically significant association was observed. Despite the relatively low prevalence, the impact of Frey syndrome on affected individuals should not be underestimated. Additional research will provide a more comprehensive understanding of the underlying factors contributing to Frey syndrome, leading to improved preventive measures and treatment strategies. A better grasp of the prevalence and associated risk factors will aid in the development of guidelines to minimize the occurrence of this syndrome.
A Study on the Subjectivity of Graduate Counseling Students’ Perception of Sandplay Therapy Using Q Methodology
Authors: Kim Hyunjo
Published: September 2023

This study investigated the perception of Sandplay therapy among graduate students majoring in counseling using Q methodology. Initially, 31 statements were extracted through literature research, and in-depth interviews were conducted with five graduate students majoring in counseling, resulting in 40 Q-samples. Subsequently, 28 graduate students majoring in counseling were selected as P samples, and Q classification was performed on them. The collected data were analyzed using the PC-QUANL program, leading to the identification of four types: “familiar positive inquiry type” (Type 1), “unfamiliar neutral avoidance type” (Type 2), “unfamiliar neutral inquiry type” (Type 3), and “familiar neutral inquiry type” (Type 4). Type 1 participants were attracted to Sandplay therapy, demonstrating a familiar and positive attitude and expressing a willingness to learn more about it. In contrast, Type 2 participants perceived no significant difference between Sandplay therapy and other counseling techniques. Type 3 participants were unfamiliar with Sandplay therapy and lacked knowledge about its attributes and advantages compared to other counseling techniques. Type 4 participants, although familiar with Sandplay therapy, also lacked awareness of its specific attributes and advantages. The study's findings are expected to serve as fundamental data for the future improvement and development of Sandplay therapy training for graduate students majoring in counseling. By shedding light on the various perceptions among students, this research can contribute to enhancing Sandplay therapy education and practice within counseling programs.
Improving public trust in vaccination programmes
Authors: Heffernan Catherine
Published: September 2023

Despite their effectiveness in preventing severe disease, vaccines are prone to controversy, so public trust is key to successful vaccination rollouts. Catherine Heffernan, director of health improvement at Southwest London Integrated Care Board, explains the key steps to address vaccine hesitancy and improve public trust in the healthcare system.
Batteries Tested to Perfection
Authors: Ko Tj
Published: September 2023

AS VEHICLE ELECTRIFICATION GAINS PACE, VERIFIED ADVANTAGES OF IMMERSION COOLING BATTERY TECHNOLOGY MEAN GREATER BATTERY SAFETY, PERFORMANCE AND LONGEVITY
Characteristics of amino acid metabolism in colorectal cancer
Authors: Xu Fen , Jiang Hong-Liang , Feng Wei-Wei , Fu Chen , Zhou Jiang-Chang
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Effectiveness of out-fracture of the inferior turbinate with reduction nasal bone fracture
Authors: Kim Se-Young , Nam Ha-Jong , Byeon Je-Yeon , Choi Hwan Jun
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Oncologic efficacy of gonadotropin-releasing hormone agonist in hormone receptor-positive very young breast cancer patients treated with neoadjuvant chemotherapy
Authors: Choi Hee Jun , Lee Jun Ho , Jung Chang Shin , Ryu Jai Min , Chae Byung Joo , Lee Se Kyung , Yu Jong Han , Kim Seok Won , Nam Seok Jin , Lee Jeong Eon , Jung Youn Joo , Kim Hyun Yul
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Effect of polyene phosphatidylcholine/ursodeoxycholic acid/ademetionine on pregnancy outcomes in intrahepatic cholestasis
Authors: Dong Xiao-Rui , Chen Qian-Qian , Xue Meng-Ling , Wang Ling , Wu Qin , Luo Teng-Fei
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Methyl-CpG-Binding protein 2 duplication syndrome in a Chinese patient: A case report and review of the literature
Authors: Xing Xu-Hang , Takam Russel , Bao Xiu-Ying , Ba-alwi Nour Abdallah , Ji Hong
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Amniotic membrane mesenchymal stromal cell-derived secretome in the treatment of acute ischemic stroke: A case report
Authors: Lin Fu-Hong , Yang Yu-Xiao , Wang Yu-Jun , Subbiah Suresh Kumar , Wu Xiao-Yun
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
Delayed-onset micrococcus luteus-induced postoperative endophthalmitis several months after cataract surgery: A case report
Authors: Nam Ki-Yup , Lee Hong-Won
Published: September 2023

In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.