bluuebunny/crossref_metadata_2025 huggingface dataset:
TEXTURAL AND STRUCTURAL REGULARITIES OF DEFORMATION BY ROLLING OF Zr-2.5%Nb ALLOY
Authors: Malykhin D.G. , Grytsyna V.M. , Kovtun K.V.
Published: October 2023

A review of studies of regularities of changes in the crystallographic texture of the longitudinal and cross rolling of the Zr-2.5%Nb alloy is given. Accordingly with this, plates were made from longitudinal fragments and rings of a tube 15.01.5 mm from the fuel assemblies of Russian RBMK reactors. The plates were annealed at 580 °C for
3 h. X-ray studies of texture changes with the degree of deformation of the plates by rolling were carried out. The principle of method of inverse pole figures was used with the calculation of the Kearns texture coefficients, as well as measurements of tilt curves (0002) was. Non-uniformiity of deformation during straightening of the tube blanks
was taken into account. It is found that the main rotations of crystallographic c-axes in the plates at any rolling direction are carried out in the plane corresponding to the cross-section of the original tube. Existence of an initial stage of increased textural changes during deformation of the plates is found, what is qualitatively and quantitatively related to activity of tensile twins of the {1012}[1011] system. Regularities in texture changes at the subsequent moderate stage of deformation with the participation of compression twins are considered. The purely twinning
nature of the textural doublet, which latter is characteristic of the rolling texture of metals of the titanium subgroup, is explained. It is noted and explained a fact that during cross rolling of plates (made from tube rings), textural changes occur at a rate twice as high as during longitudinal rolling. As considered, all similar regularities can be
carried out for the metals of the titanium subgroup.
DAMAGE TO THE HEAT EXCHANGE SURFACE OF STEAM GENERATOR PGV-1000
Authors: Gozhenko S.V. , Krainiuk Y.O. , Mitrofanov A.S.
Published: October 2023

A comprehensive analysis of the damaged heat exchange surface of the PGV-1000 steam generator during long-term operation, their relationship with hydrodynamic, water-chemical regimes and surface properties was conducted. The methods of minimization of damages during the operation of Ukraine's NPP are considered.
RESEARCH INTO THE EFFECT OF PARTICLE SIZE DISTRIBUTION OF NEUTRON-ABSORBING POWDER MATERIALS ON THE COMPACTION IN ABSORBING ROD CLADDINGS
Authors: Chernov I.O. , Belash M.M. , Romankov V.O. , Yevseyev V.M. , Legenkyi Y.S.
Published: October 2023

The results of research into the effect of the granulometric compositions of neutron-absorbing powder materials such as boron carbide, dysprosium titanate and dysprosium hafnate and their mixtures in the initial state on the characteristics of backfills in the claddings of both “short” and full-size absorbing rods are presented. It was revealed
that the achievement of the maximum backfill density is facilitated by providing the content of a fine fraction of about 30%. The maximum backfill density values achieved for boron carbide, dysprosium titanate, and dysprosium hafnate were 1.82, 5.1, and 5.82 g/cm3 respectively. The optimal modes of vibration compaction (type and frequency
of oscillations), which ensure the achievement of the required values of the backfill density in absorbing rods in a short time were defined.
TECHNOLOGICAL BASIS OF THE PROCESS OF ZIRCONIUM AND HAFNIUM SEPARATION
Authors: Mukhachev A.P. , Yelatontsev D.O. , Kharytonova O.A. , Shevchenko V.G.
Published: October 2023

The paper presents the results of industrial testing of the process and equipment for the extraction separation of zirconium and hafnium in a single technological cycle with the production of high-purity nitrate compounds and pure nitric acid solutions as raw materials for the production of sodium nitrate. It is shown that the efficiency of the
extraction process is determined primarily by the purity of the nitric acid solution by the content of a critical impurity – silicic acid, which causes an undesirable emulsification process and disrupts the stability of the process. Optimal conditions have been determined under which the formation of non-extractable forms of zirconium and
hafnium is excluded. The replacement of pulsating columns with centrifugal extractors reduced operating costs by reducing the volume of a one-time load of a flammable extractant and its losses as a result of hydrolysis. This increased the degree of separation of zirconium and hafnium. Centrifugal extractors provided high process kinetics,
reduced production areas, and increased labor productivity and product quality.
REVIEW KARAKTERISTIK SORGUM MANIS (Sorghum bicolor L. Moench) SEBAGAI BAHAN BAKU PRODUKSI BIOETANOL
Authors: Dhuha Naga Syamsi , Izza Zulfa Falihil
Published: October 2023

Sweet sorghum (Sorghum bicolor L. Moench) is a cereal plant that is able to grow in a relatively harsh environment and can be cultivated in Indonesia even though it is not a tropical plant. This plant has the potential to be used as raw material in making bioethanol because in addition to being environmentally friendly, the raw materials are also very abundant, so it can be an alternative substitute for gasoline. The weight of the stem biomass, the percent of brix nira, and the volume of sap contained in the superior genotype of sweet sorghum for bioethanol production. The results obtained from stem biomass, percent brix in stem sap, and high volume of sap can be used as criteria for selecting varieties for bioethanol raw materials from sweet sorghum.
EKSTRAKSI PEKTIN KULIT KAKAO (Theobroma cacao L.) MENGGUNAKAN METODE MICROWAVE ASSISTED EXTRACTION DENGAN ASAM KLORIDA
Authors: Prasetyo Adji , Nadir Mardhiyah , Sari Wanda Erwinda , Rahmaniar Zhafirah Zanetti
Published: October 2023

Produksi buah kakao perkebunan rakyat di Indonesia mencapai 703.600 ton/tahun.  Kulit buah kakao mengandung senyawa pektin sebesar 25-29% pada buah kakao muda (mengkal) sedangkan pada buah kakao matang sebesar 8-11%. Pektin digunakan dalam industri pangan, kosmetik, maupun farmasi. Pemisahan pektin dari jaringan buah dapat dilakukan dengan metode ekstraksi. Tujuan dari penelitian ini untuk mengetahui pengaruh rasio bahan terhadap pelarut (b/v) pada ekstraksi pektin dari kulit buah kakao menggunakan metode Microwave Assisted Extraction (MAE). Kulit buah kakao diekstraksi sebanyak 20 gram dengan pelarut HCl 0,25% pada daya 300 watt selama 30 menit menggunakan variasi rasio bahan terhadap pelarut ( 1:15, 1:20, 1:25, 1:30, 1:35, dan 1:40). Hasil ekstraksi dianalisa dengan uji kualitatif FTIR serta uji kuantitatif (rendemen, kadar air, kadar abu, berat ekivalen, kadar metoksil, kadar galakturonat dan derajat esterifikasi). Hasil Analisa uji FTIR pada pektin menunjukkan panjang gelombang gugus fungsi hidroksil (3356,36 cm-1), alkil (2921,99 cm-1), eter (1229,74 cm-1) dan karbonil (1732,82 cm-1). Rendemen terbaik dihasilkan pada variasi rasio 1:20 sebesar 5,74% dengan karakteristik pektin yaitu kadar air sebesar 11,45%, kadar abu sebesar 0,96%, berat ekivalen sebesar 621,30 mg, kadar metoksil 15,17% (metoksil rendah), kadar asam galakturonat sebesar 48,09%, dan derajat esterifikasi sebesar 61,09% (ester tinggi). Hasil analisa karakteristik sudah memenuhi standar IPPA.
EKSTRAKSI PEWARNA ALAMI DARI KAYU ULIN BERBANTUKAN ULTRASONIK
Authors: Dewi Firda Kusuma , Fahreza Fahmi , Arifin Zainal , Sirajuddin Sirajuddin , Sahraeni Sitti
Published: October 2023

Pengolahan kayu ulin melalui proses penggergajian menghasilkan limbah berupa serbuk kayu sebanyak 10%. Uji fitokomia menunjukkan bahwa serbuk kayu ulin mengandung zat warna alami yang dapat digunakan sebagai alternatif pewarna sintesis. Zat warna alami dapat diambil dengan proses ekstraksi. Salah satu metode ekstraksi modern yang dapat digunakan adalah metode ekstraksi ultrasonik atau disebut Ultrasound Assisted Extraction (UAE). Penelitian ini dilakukan untuk mengetahui pengaruh jarak transduser dan ukuran partikel pada ekstraksi zat warna alami dari serbuk kayu ulin berbantukan ultrasonik. Bahan baku berupa limbah serbuk kayu ulin dihaluskan dengan blender kemudian diayak dengan ayakan 20, 40, 60, 80, 100, dan 120 mesh. Sejumlah 20 gram serbuk kayu ulin ditambahkan pelarut etanol 96% sebanyak 250 mL dalam erlenmeyer kemudian diletakkan dalam reaktor ultrasonik. Selanjutnya mengatur jarak tranduser dan menyalakan ultrasonic generator. Ekstraksi dilakukan selama 20 menit kemudian hasil ekstraksi disaring. Filtrat didistilasi untuk memisahkan pelarut. Residu disentrifugasi selanjutnya dikeringkan dalam oven hingga diperoleh berat konstan dan dihitung rendemennya. Berdasarkan hasil penelitian diketahui arak optimum transduser adalah 3 cm dengan rendemen 5,37%. Sedangkan ukuran partikel terbaik yaitu -120 mesh dengan rendemen 3,56%.
Critical Understanding of Myasthenia Gravis on the Basis of Vyadhi Ghatak
Authors: Dipali Thakor  , Manish Patel  , S N Gupta  , Suppose Maurya
Published: October 2023

Myasthenia gravis (MG) is an autoimmune neuromuscular junction (NMJ) disorder characterized by weakness and fatigability of skeletal muscles. Myasthenia gravis has prevalence as high 200 in 100,000. It affects individuals in all age groups, but peak incidences occur in women in their twenties and thirties and in men in their fifties and sixties. Overall, women are affected more frequently than men, in a ratio of 3:2. It has bimodal age distribution. In MG, the fundamental defect is a decrease in the number of available AChRs at the postsynaptic muscle membrane. It presents with fluctuating skeletal muscle weakness and fatigue most commonly affecting the ocular muscles, although any muscle may be affected. In modern science treatment of Myasthenia gravis include anti-cholinesterase medications, glucocorticoids and other immunosuppressive agents. Long term use of steroid and immune modulator drugs has many adverse effects on other system of body. Ayurvedic therapies can give much more promising results. Comparison between myasthenia gravis and diseases explained in Ayurveda is difficult and exact correlation is not possible. But based on critical understanding of Vyadhighataka, a probable diagnosis can be made and treated accordingly. In this article, attempt is made to understand the pathogenesis of myasthenia gravis by considering the concepts of Dosha (vitiated Dosha), Dushya (vitiated Dushya), Aama, Agnimandya, and Srotovaigunya. For any disease pathology to begin, all components must be present. Pathogenesis of any disease will not occur without these elements.
Role of Kanchanara Twaka Kwatha with Shunthi Churna in Hypothyroidism (Dhatuwagni Vikriti)
Authors: Radha Joshi  , OP Singh  , Sanjay Kumar Tripathi
Published: October 2023

The thyroid is an important part of human endocrine system which are responsible for regulation of oxygen use, BMR, cellular metabolism and growth and development. Hypofunctioning of Jatharagni which in turn effect Dhatwagni eventually brings out Pathological sequence and ultimately the disease condition develop. In hypothyroidsim etiological factors mainly vitiate Tridosha (Kapha predominance along with Pitta vitiation and Margavarana leading to provoking of Vata). The line of treatment with specific target to Rasavaha, Mamsavaha, Medovaha, Manovaha Srotas as well as Vata-Kapha Nashaka, Agnideepan, Sroto Shodhana, Vatanuloman, Amapachan treatment should be administered in hypothyroidism. Keeping the same in mind, present study was carried out to assess the role of Kanchanara Twaka Kwatha with Shunthi Churna in hypothyroidism (Dhatuwagni Vikriti). For this study 40 patients were selected and are divided into two groups with 20 patients in each group on the basis of inclusion and exclusion criteria and were assessed on the basis of subjective and objective parameters by applying appropriate statistical test. Most of the patients in group 1 (Kanchanaradi Kwatha) shows marked improvement in their symptoms as well as in objective parameters (thyroid profile) as compared to group 2 (Tab. Levothyroxine 50 mcg) which was taken as control group. From this study it can be concluded that hypothyroidism can be managed effectively with Kanchanara Twaka Kwatha with Shunthi Churna mention in Sharangdhar Samhita Madhyam Khanda Adhyaya 2 Shloka no.126.
Efficacy of Ayurveda Polyherbal Medicine in Polycystic Ovarian Syndrome
Authors: Akanksha Mishra  , Lowkesh Chandravanshi  , Lalit Mohan Bhatt
Published: October 2023

The most prevalent rising health risk for women of reproductive age is polycystic ovarian syndrome, a heterogeneous endocrine condition. The polycystic ovarian syndrome (PCOS) is a prevalent endocrinopathy that is multifactorial and polygenic and is characterized by several tiny ovarian cysts, oligo-ovulation or anovulation, and indicators of hyperandrogenism, differ from person to person throughout time. Here is a case report of a 15-year-old girl who presented with hirsutism, irregular menstruation and constipation, her USG report showed bilateral PCO pattern. Based on the clinical features, treatment principles adopted are Aam paachana, use of Arthava janana Dravya, Vata anulomana and Granthi nashak chikitsa. Initially, after 2 months of treatment menstruation became normal and marked reduction in the symptoms was found. Moreover, the hormonal level became normal after 6 months of treatment. This case study is an example that PCOS can be effectively managed by adhering to Ayurvedic principles.
Ayurveda Perspective on Visarpa Vyadhi and its Management
Authors: Yogesh T. Kotangale  , Anuja S. Bhojane  , Sumedha Y. Kotangale
Published: October 2023

Skin is the largest organ of the body which acts as a first line of defense in providing resistance to the body. The aggravation of various Dhatus and Doshas result in skin diseases. More than one-fifty skin related diseases are mentioned in various Ayurvedic texts. They are categorized as Visarpa, Kustha, Shotha, Upadansh etc. Visarpa is a very common disease mentioned in Ayurvedic texts which spreads in body in various directions. It is said to be caused by Varicella zoster virus as per modern concept. It manifests as Daha, Jwara, Anunnatashopha and Vedana. Around 20-30% sufferers of various skin ailments are demonstrated through large community prevalence study. A 40-year-male presented along with the vesicular lesions on his neck region associated with mild fever, itching, and pain on the local lesion. He was administered with 250mg of Kamadudha rasa (plain) twice a day before meals with milk, Chandrakala rasa 250mg twice a day, Paripathadi kwatha 2 tsp twice a day and Shatadhauta ghrita for local application on the lesions. The patient reported on the 5th day with significant relief in the size and shape of the facial lesions and other symptoms. The scars limited to minimal without any inflammatory signs by the 7th day of follow-up. Above medications are two readily available and cost-effective compound Ayurvedic formulations, which can be used in the management of herpes zoster infection, especially in low-resource settings.
Osmotic Demyelination Syndrome after Correction of Hyponatremia
Authors: Anila B. Nair  , Pravith N. K  , Sreekutty R. S
Published: October 2023

Osmotic demyelination syndrome is a rare neurological disease resulting in cerebral apoptosis and loss of myelin due to osmotic stress. Based on anatomical localization and pathological attributes, ODS can be categorized as Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). It has a biphasic course, with first phase reflecting electrolyte imbalance and the second with pontine dysfunction, impaired vigilance and movement disorders. In an autopsy-based study, a prevalence rate of 0.25–0.5% was seen in the general population and 10% in patients undergoing liver transplantation. Being a rare disease with variable, but preventable outcome, the present case was managed with Ayurvedic oral medication and Panchakarma therapy with an aim to improve the quality of life. In Ayurvedic perspective, Vata kshaya lakshanas occur during the phase of hyponatremia and further correction of this leads to disruption of osmolality (Kapha pitta accumulation) resulting in Avarana of Vata. This may be the reason for demyelination and localisation of Vata in Sira and Snayu leading to Sira snayu shoshana on both halves of the body resulting in Sarvangaroga (full body afflicted with Vata). Thus Avaranahara, Srotosodhana and Vatanulomana principles were adopted. An improvement in Barthel index and modified rankin scale were observed after a course of treatment for 30 days.
Câncer de próstata: revisão integrativa sobre a atuação do enfermeiro na atenção primária à saúde
Authors: Macena Luiz Felipe da Costa , Alencar Neta Raimunda Leite de , Silva Francisca Mayara Gabriel da , Feitosa Ankilma do Nascimento Andrade , Quental Ocilma Barros de , Medeiros Renata Lívia Silva Fonseca Moreira de
Published: October 2023

Introdução: O Instituto Nacional de Câncer (INCA) afirma que o câncer de próstata é um dos mais comuns entre os homens, perdendo apenas para o câncer de pele não melanoma. O enfermeiro desempenha um dos papéis mais importantes na Estratégia Saúde da Família (ESF), entendendo os princípios e diretrizes que regem a atenção primária, segundo a Política Nacional de Atenção Básica (PNAB). Objetivo: analisar a atuação da equipe de atenção primária à saúde frente ao câncer de próstata. Método: Trata-se de um estudo do tipo revisão integrativa da literatura, em que foi realizado, por meio de um levantamento de dados, nas bases científicas: LILACS, SCIELO e BDENF disponíveis na BVS. Mediante a aplicabilidade dos critérios de elegibilidade definidos, selecionou-se sete estudos para compor a amostra dos resultados. Resultados e Discussões: Foi constatado que um dos fatores que influenciam a resistência dos homens ao serviço de saúde pode estar diretamente relacionado ao desconhecimento da política destinada ao público (PNAISH), horário de funcionamento do serviço de saúde e direitos. Conclusão: Evidenciou-se que há evasão masculina nos serviços de saúde, devido ao estereótipo masculino, permitindo demonstrar que as dificuldades existem, embora haja caminhos que podem ser traçados para reverter esse cenário.
Efficacy and safety of Vicia faba L. extract compared with levodopa in management of Parkinson’s disease and an in‐silico phytomedicine analysis
Authors: Nikkhah Karim , Shoeibi Ali , Rezaeitalab Fariborz , Aminzadeh Samira , Sharara Hussein , Abbas-Mohammadi Mahdi , Al-attar Mohammad , Akbari Mohammadeza , Moradi Fereydun , Rakhshandeh Hasan , Saeidi Morteza
Published: October 2023

Background: Parkinson’s disease is a chronic degenerative disease of the central nervous system, presently lacks an effective therapy for its complex pathogenesis. Agents containing Levodopa can alleviate its symptoms. Hypothesis Vicia faba L. (Fava bean) extract may prove a useful antiparkinsonian agent similar to Levodopa. Methods: Thirty patients with Parkinson’s disease, entered into this cross over clinical study. In the first step, each participant received V. faba L. extract containing 106.5 mg of Levodopa. After a wash out period of 7 days, the patients entered the second step during which they received conventional treatment with Levodopa-C tablets. Blood Levodopa were measured 4 hours and 8 hours after each administration. The Movement Disorder Society-Unified Parkinson’s Disease Rating Scale was employed to measure the therapeutic effects in each step. Additionally, a docking analysis was performed to distinguish the chemical constituents of the plant and six key mediators actively involved in Parkinson disease. Results: The fava bean extract significantly alleviate all studied end points except for tremor at rest and freezing. Wilcoxon Signed Ranks Test showed that there was not a significant difference between rigidity, rising chair, gait and bradykinesia. Docking results of the herb components and standard ligands, indicating that the antiparkinsonian activity of V. faba could presumably be related to many phytochemicals. Conclusion: This study showed a beneficial effect of V. faba L. similar to Levodopa-C. and better compliance due to lower adverse events.
A Survey of Ethnomedicinal Plants used for Urinary Tract Infection (UTI) and Kidney Stone in the Nalbari, Sonitpur and Tinsukia Districts of Assam, India
Authors: Ali Akib , Khanikar Debashish , Kataki Bidisha
Published: October 2023

Natural products derived from plants have essential biological parts in contradiction of many pathogenic organisms and are considered a principal source of modern synthetic drugs. A thorough field survey of ethnomedicinal plants was conducted between the months of July, 2022 to December, 2022 in three districts of Assam, namely Nalbari, Sonitpur and Tinsukia. Indigenous knowledge of the traditional medicines used for Urinary Tract Infection (UTI), Urinary Tract stones or kidney stones were gathered based on personal interviews and questionnaires. Medicinal plants with their family, local names, parts used and target diseases were documented. A total of 51 species were documented; of which, amaranthaceae family showed the highest number of species (6), followed by malvaceae (4), fabaceae (3), euphorbiaceae (3), asteraceae (3) etc. This survey revealed several effective medicinal plants that have significant pharmacogenetic properties, especially for UTI and kidney diseases.
Efficacy of Yashtimadhu ghrit matra basti in post-operative management of Ano-rectal Cases – A case Series
Authors: Jaivarshaa Pavithra , Dasar Devyani , Kumar Akshay
Published: October 2023

Background- Exploitation of analgesics is becoming an advent scenario in the current practice of both medical and surgical cases. Adopting a less complicated and a wholesome beneficial modality for post operative analgesia is the need of the hour. In this case series, focus has been placed on yashti ghrit matra basti as the intervention for pain and wound management of post-operative cases of chronic fissure in ano associated with internal haemorrhoids. Objective- The current study was aimed at post operative analgesia and wound management with yashti ghrit matra basti in ano-rectal cases. Material & Methods-The method adopted here was Lord’s anal dilatation followed by excision of sentinel tags or ligation haemorrhoidectomy according to the case presentation, followed by yashti ghrit mastra basti as primary ayurvedic intervention for post operative analgesia and wound healing. Results -It is found that the planned treatment gave a positive response as post operative analgesia and also played an adjuvant role in wound healing. Conclusion-This case series provides the successful pain and wound management of post-operative ano-rectal cases with a promising ayurvedic intervention.
Vatsanabha (Aconitum ferox Wall. ex Seringe): A known Visha but potent medicine W.S.R. Rasa Ratna Samuchchaya
Authors: Gajanan Masal Aishwarya , Abhay Shinde Arati
Published: October 2023

Ayurveda is an ancient science dominantly focuses on healthy living and mindful life in contrary to other medical sciences. Ayurveda specifically uses herbs and herbo-mineral combinations for the treatment. The herbs described in the classics also include some Vishadravya (poisonous plants) as potent medicine. Anything that results in "Vishannatva" (stress) or "Vishada" (sadness) in the body is "Visha" (poisonous material). Depending on the intensity of toxicity, Ayurvedic classics have classified all poisons into two categories: Mahavisha and Upavisha (less potent toxin). Vatsanabha (Aconitum ferox Wall. ex Seringe) is classified under the Sthavara Visha (poison of plant origin) and Mahavisha. It is the only Mahavisha that is still recognised and available. All Vishadravya should be used after some specific Shodhana (purification). While administering Vatsanabha in the form of Ayurvedic medicines, Shodhana (purification) is an effective technique for minimising its hazardous effects. Although it is Vishadravya, the compounds containing Vatsanabha (Aconitum ferox Wall. ex Seringe) are listed in ‘Essential Ayurveda Medication for Ayurvedic dispensaries, operated under centrally supported programmes of the Government of India. This enlistment affirms its significance in other ways. Nearly 17 percentage of the formulations mentioned in RRS have Vatsanabha as their constituent. Modern research has already proven the analgesic, antipyretic, antioxidant, antimicrobial and many other activities of Vatsanabha. Thus, the present review is designed to extensively discuss and understand the safety profile of Vatsanabha and utility in various diseases, along with its probable mode of action.
Evaluation of acute toxicity of Rasaparpati - An Ayurvedic mercurial compound in Albino rats
Authors: Meher Lily , Ratha Kshirod Kumar , Das Arun Kumar
Published: October 2023

Background

This study aimed to investigate the preparation process of Rasaparpati, an Ayurvedic medicine containing Mercury that is commonly used to treat various ailments. The dangers of using Mercury as a therapeutic agent are acknowledged, and Ayurveda emphasizes purifying heavy metals before human use. The present study assessed the acute toxicity of Rasaparpati in albino rats to ensure its safe consumption.

Methodology

Following ethical guidelines and O.E.C.D. (423) protocol, Rasaparpati was prepared traditionally, and an acute toxicity study was conducted. Two groups of female Wistar rats were administered 300mg/kg and 2000mg/kg of Rasaparpati, and their behavioral changes, signs of toxicity, and mortality were closely monitored. Hematological, biochemical, and histopathological parameters were also examined for any changes. The data obtained were analyzed and evaluated using an unpaired t-test, with p < 0.05 considered significant.

Results

No deaths were observed following the administration of Rasaparpati in an acute toxicity study. There were no hematological or biochemical toxicity indications, even at ten time the therapeutic dose. However, the histopathological analysis revealed mild changes likely to heal and repair. These non-specific and reversible changes in rat cells suggest similar outcomes in human cells.

Conclusions

The acute toxicity study of Rasaparpati suggests its safety for animal use, indicating potential safety for human consumption. No adverse effects or mortality were observed, even at a dosage ten times higher than the therapeutic dose. However, more extensive research with larger sample sizes and control groups is recommended.
Clinical study of add on effect of Triphaladaruadi Kwatha (Vangsenokta) along with antidiabetic drug in management of Prameha (Non-Insulin Dependent Diabetes mellitus- NIDDM)
Authors: Lagad Abhilasha C , E Gogate Vishwas , Khan Almas Y , Kombe Pooja S , N Mane Pallavi , Abhijit Shekhar
Published: October 2023

Prameha (Diabetes mellitus) is an age long disease known from vedic period and now it is a leading lifestyle disorder. Diabetes mellitus is a group of metabolic syndromes of fat, protein and carbohydrate which is due to absolute or relative deficiency of insulin. The prevalence of diabetes in India has risen from 7.1% in 2009 to 8.9% in 2019.1 The estimates in 2019 showed that 77 million individuals had diabetes in India, which is expected to rise to over 134 million by 2045.2 In India, it is also 3rd leading cause of death (After heart disease and cancer). The number is projected to be twice by 2030. Type 2 diabetes makes up about 85-90% of all cases. Increase in the overall diabetes prevalence rates largely reflect an increase in risk factors for type 2, notably greater longevity and being overweight or obese. Hence preventive measures are essential and an ideal therapy is still obscure. It remains one of the baffling enigmas for clinical research. This is a randomized single blind standard controlled clinical trial conducted on 66 patients of Prameha (Type II DM & who are on antidiabetic treatment) to rule out Add on effect of Triphaladaruadi kwath of either gender between age group of 40-60 years and grouped into Group A & Group B. 33 patients in group A were on Antidiabetic drug (Metformin 500mg OD/BD and 33 patients in Group B are on same antidiabetic drug (Metformin 500mg OD/BD) with additional Triphaladaruadi kwath (Decoction) for 3 months. Results obtained in subjective and objective parameters were analyzed for the statistical significance by adapting paired ‘t’ test in the groups, Two-way ANOVA test between the groups, and Wilcoxon rank sum test. The study revealed that Group B was found to be more effective in bringing symptomatic relief and improving biochemical markers in the patients of Prameha.
A Comparative Pharmaceutical Study of Abhrasindoora by Traditional and Contemporary Method
Authors: Bramhankar Rakesh , Mishra Abhaya Kumar , Munishwar Nisha , Baruah Himangshu , Mandal Snigdha
Published: October 2023

Background: Rasashastra is a Pharmacotherapeutics of Mercurial, Metallic, and Mineral preparations Abhrasindoora (AS) is a unique Herbo-Metallic-Mineral Compound, which is mainly indicated in respiratory diseases. Method: AS contains Dhanyabhraka (Bio-purified Black Mica Powder), Shodhita Parada (Bio-purified Mercury), and Shodhita Gandhaka (Bio-purified Sulphur) in equal proportion. These mixtures were subjected to trituration in Kharal till Kajjali formation (ABS-72 hrs) followed by impregnation of latex of Arka (Calotropis procera linn) (QS) (16 hrs) and Vatashunga (Ficus benghalensis linn) (QS) (15 hrs). Then Batch-A & Batch-B were prepared separately in Valuka Yantra and Electric Muffle furnace by maintaining mild (150 0C-250 0C), (150 0C - 300 0C) moderate (250 0C -400 0C), (300 0C -450 0C) and intense temperature (400 0C - 550 0C), (450 0C -650 0C) respectively. Observation: Batch A AS was prepared in 37 hours and the total yield of the product obtained was 54 grams. Batch B AS was prepared in 21 hours and the total yield of the product obtained was 25 grams. Jet black colour Kajjali of AS turned to dark red which was sublimated at the neck of Kachkupi. Conclusion: The yield of Batch A was more than Batch B but it took more time. Hence, the preparation of Kupipakva Rasayana in a sand bath should be done repeatedly to conclude it is a more economic and convenient process.
Role of Panchakarma in the Management of Spinal Canal Stenosis - A Case Study
Authors: G Anjali , T Sangeeta , M Parappagoudra , G Dash
Published: October 2023

Spinal canal stenosis is a painful, degenerative condition, and is localized to facets, joints, and ligamentum flavum of the vertebra which is often referred to for surgical correction. The main cause of stenosis is herniated vertebral disc. If there is no compression, the spinal canal can be referred to as narrow, but not stenotic. Certain studies have defined lumbar spinal stenosis as the narrowing of the osteo-ligamentous vertebral canal or the intervertebral foramina, which causes compression of the thecal sac or the caudal nerve roots. The narrowing may impact the entire canal or just a portion of it, but it occurs at a single vertebral level. In this condition, it may, drastically affect the quality of life due to severe pain in doing daily routine activities. In contemporary science, there is no treatment except surgical intervention which is having a high chance of complication and the chances of recurrence. Surgery is necessary when there are clinically significant motor deficiencies or symptoms of cauda equina syndrome. Based on the manifestation of clinical signs and symptoms it can be correlated with Gridhrasi, according to Ayurveda. Gridhrasi can be treated successfully by the intervention of Panchakarma procedures along with Shamana Chikitsa. Here is a case study of a patient suffering from low back pain radiating to bilateral lower limbs, stiffness, numbness, burning sensation in the bilateral sole region, and unable to walk without support, who was previously diagnosed as a case of Spinal Canal Stenosis. He was treated with a Panchakarma procedure, Shamana Chikitsa along with Physiotherapy Exercises. The patient showed marked improvement and could do daily routine activities properly.
Variations in the severity of symptoms, DAS28, and Disability Index among different Vata predominant Deha-Prakriti individuals of Amavata (~Rheumatoid Arthritis) - An Analytical Observational Study
Authors: Chinthala Rajkumar , S B Kamble , NNL Bhagavathi , A S Baghel
Published: October 2023

Background: Subgrouping of diseased population, based on Deha-Prakriti (DP), phenotypic classification of Ayurveda will explore the variation in the disease severity, which further aid in the management of the disease more precisely and selectively. But there is a paucity in the data generation. Amavata (~Rheumatoid Arthritis) is one of such diseases, resulting from the conglomeration of Ama and aggravated Vata gets lodged in the joints. Aim & Objective: To evaluate variations in the severity of symptoms, duration of morning stiffness, DAS28 (Disease Activity Score in 28 Joints), and Disability Index (DI) among different Vata predominant Deha-Prakriti (DP) individuals of Amavata (~Rheumatoid Arthritis). Materials & Methodology: The study was conducted among 155 clinically diagnosed patients of Amavata, who were screened for DP assessment through the CCRAS-PAS scale. Those who were found to have Vata predominant DP were sub-grouped into Single Vataja (V), Vata-Pittaja (VP), and Vata-Kaphaja (VK) DP, based on the proportion of the doshas in the output of scale. Demographic profile, the severity of the symptoms, duration of the morning stiffness, DAS28, and DI were assessed and calculated using SPSS software version 20.0, p≤0.05 was considered statistically significant. Results: Kruskal-Walli’s test revealed that Single Vata predominant DP patients were found to have severe Sandhi-shula (Joint pain) (p<0.0001), Shunatanga (Numbness of the joint) (p-value at 0.0069), Nidra-Viparyaya (Irregular sleep patterns) (p-value at 0.0012) than VP and VK DP individuals. Sandhi-Shotha (Joint swelling) (p-value at 0.0299), Angamarda (generalized body pains) (p-value at 0.0130), Alasya (laziness) (p<0.0001), Gaurava (Heaviness) (p<0.0001), and Apaka (delayed digestion) (p-value at 0.0254) were found severe in VK DP, whereas Trishna (Thirsty) (p<0.0001), Nidraviparyaya (p-value at 0.0012) were more severe in VP DP individuals. One-way ANOVA revealed that the duration of morning stiffness (2.03±0.2 hours, p-value at 0.446), DAS28 (6.85±0.175, p-value at 0.0035), and DI (1.87±0.54, p-value at 0.0003) were found significantly high in single Vataja than VP and VK Deha-Prakriti. Conclusion: The disease severity in terms of duration of morning stiffness, DAS28, and DI were found more severe in Single Vataja DP. The severity of the signs and symptoms also varied according to DP.
Ethnozoological survey of Non conventional food items and their therapeutic use by the traditional healers of Dhemaji district of Assam, North-East India
Authors: Gogoi Mallika , Chakravorty Jharna
Published: October 2023

Assam one of the North Eastern states of India is gifted with diverse natural resources and inhabited by varied ethnic communities. Dhemaji district of Assam is also not exceptional in this regard. A survey was conducted on zootherapeutics among the traditional healers of Dhemaji district through personal interview from 2016 January to 2017 January in fifteen non tribal inhabited villages among 75 respondents of the age group 50-70years. It was documented that the ethnic people of Dhemaji used a total of 26 species of non conventional food items for their therapeutic value against various ailments including itching, burning, asthma, paralysis, weakness etc. These species include varieties of vertebrate and invertebrate species such as arthropods, molluscs, amphibians, aves, reptiles, pisces and mammals depending on their seasonal availability. The highest no of animal species used for the traditional therapeutics is mammals (29%) followed by pisces (19%), arthropoda and reptiles(15%), aves (13%) and the least are amphibia and mollusca (each comprises only 4% species). The study reveals that the ethnic people of Dhemaji are rich in traditional therapeutics and proper documentation and scientific analysis may lead to new drug discovery and conservation of these valuable faunal species.
Clinical Evaluation of Pleurotus florida (White Oyster Mushroom) – Chatraka in the management of Vitamin D deficiency
Authors: Nair M K Smitha , Parmar Rekha , Talwar Anurag , Nair M K Sabitha , V Subhose
Published: October 2023

Oyster mushroom (Pleurotus florida) commonly called in India as 'dhingri' develops spontaneously on dead and rotting wooden logs or sporadically on dying trunks of deciduous or coniferous trees in temperate and tropical woodlands. On exposure to sunlight or UV lamp, oyster mushrooms produce concentrations of Vitamin D that are nutritionally significant. Though long periods of storage and different types of cooking tend to decrease the vitamin D level of UV-exposed oyster mushrooms, the vitamin D level in all probability expected to remain at 10ug/100g fresh weight, which is greater than the amount in the majority of foods containing vitamin D and comparable to the recommended daily intake of vitamin D at the global level. Eligible candidates (n=50) were screened by computerized randomization method to receive Pflorida soup during the 03-month study. The efficacy parameters were evaluated through the blood investigation Vit D 25 (OH).
Analisis Regresi Logistik untuk Menentukan Faktor-Faktor yang Mempengaruhi Kesejahteraan Masyarakat Kabupaten/Kota di Pulau Nias
Authors: Situngkir Rahel herina , Sembiring Pasukat
Published: October 2023

Regresi logistik adalah metode yang mendeskripsikan korelasi antara satu atau lebih variabel bebas terhadap satu variabel terikat yang bersifat binary. Kesejahteraan masyarakat merupakan konsep multi indikator yang menunjukkan ukuran keberhasilan pembangunan suatu wilayah. Indeks Pembangunan Manusia (IPM) merupakan indikator yang digunakan dalam mengukur kesejahteraan dan keberhasilan pembangunan. Menurut data BPS pada tahun 2020, wilayah di kepulauan Nias memiliki angka IPM yang rendah bila dibandingkan dengan wilayah lain di Provinsi Sumatera Utara. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi kesejahteraan masyarakat di Pulau Nias dengan menggunakan regresi logistik biner. Metode regresi logistik dipilih karena variabel terikat pada penelitian ini bersifat kategori yaitu tidak sejahtera (0) dan sejahtera (1). Variabel bebas yang digunakan dalam penelitian ini adalah kemiskinan (X1), gini ratio/ketimpangan pendapatan (X2), pengangguran (X3), keluhan kesehatan (X4), pertumbuhan ekonomi (X5). Dari hasil penelitian faktor yang mempengaruhi kesejahteraan masyarakat yang ada di Pulau Nias adalah ratio gini atau ketimpangan pendapatan, pengangguran dan pertumbuhan ekonomi. Dengan model regresi logistik yang terbentuk adalah g(x) = 2,781 - 0,022 X1 - 1,901 X2 - 2,783 X3 - 0,701 X4 + 1,654 X5. Dalam regresi logistik, cara untuk menginterpretasikan koefisien adalah odds ratio. Pada penelitian ini, odds ratio yang paling besar dihasilkan oleh variabel pertumbuhan ekonomi, maka dapat dikatakan pertumbuhan ekonomi merupakan faktor yang paling berpengaruh terhadap kesejahteraan masyarakat di Pulau Nias.
Penerapan Metode Analythical Hierarchy Process Pada Penetapan Pegawai Terbaik PT. Berlian Eka Sakti Tangguh Medan
Authors: Rajagukguk Nelly Anggaraini , Nababan Esther Sorta Mauli
Published: October 2023

Pegawai merupakan salah satu aset terpenting yang dimiliki oleh perusahaan dalam memenangkan persaingan di dunia bisnis yang kompetitif. Salah satu cara yang dilakukan perusahaan untuk memacu kinerja pegawai adalah dengan menetapkan pegawai terbaik. Pegawai terbaik akan diberikan penghargaan yang layak oleh perusahaan sehingga akan lebih termotivasi untuk bekerja. Dalam melakukan penilaian kinerja, perusahaan terkadang mengalami kesulitan karena tidak menggunakan metode yang dapat menangani permasalahan prioritas dengan banyak kriteria. Untuk membantu menyelesaikan masalah tersebut digunakan metode Analytical Hierarchy Process (AHP). Metode ini dikembangkan oleh Thomas L. Saaty, seorang matematikawan dari University of Pittsburgh. Metode AHP mengubah masalah multikriteria yang kompleks menjadi suatu hirarki. Hirarki membuat masalah yang rumit menjadi lebih terstruktur. Penelitian ini bertujuan untuk mendapatkan ranking dari indikator penetapan pegawai terbaik menggunakan metode AHP. Berdasarkan perhitungan yang dilakukan, pegawai dengan nilai bobot 0,0762 atau 7,62% menempati rangking pertama. Pegawai tersebut layak ditetapkan menjadi pegawai terbaik PT. Berlian Eka Sakti Tangguh Medan.
Pengunaan Model Problem Based Learning (PBL) dalam Meningkatkan Kemampuan Komunikasi Matematis Siswa
Authors: Siswadi Siswadi , Saragih Risna Mira Bella , Wardana Gusti
Published: October 2023

Penelitian ini memiliki dua tujuan utama: 1) Mendeskripsikan dan menganalisis perbedaan kemampuan komunikasi matematis siswa yang diajarkan melalui model Problem-Based Learning (PBL) dengan siswa yang diajarkan melalui model pembelajaran ekspositori. Dalam hal ini, penelitian bertujuan untuk membandingkan hasil kemampuan komunikasi matematis siswa antara kedua model pembelajaran tersebut. 2) Menganalisis apakah terdapat interaksi antara kemampuan awal matematika (KAM) siswa dan jenis pembelajaran terhadap kemampuan komunikasi matematis siswa. Tujuan ini melibatkan penelitian tentang apakah pengaruh model pembelajaran terhadap kemampuan komunikasi matematis siswa dipengaruhi oleh kemampuan awal matematika mereka. Penelitian ini menggunakan metode eksperimen. Populasi penelitian terdiri dari siswa di SMK Swasta Muhammad Yaasiin Sei Lepan, sedangkan sampel penelitian ini terdiri dari siswa kelas XI-1 dan XI-2 pada jurusan TKJ. Dari kedua kelas tersebut, kelas XI-1 dijadikan sebagai kelompok eksperimen yang mendapatkan pembelajaran melalui model PBL, sedangkan kelas XI-2 dijadikan sebagai kelompok kontrol yang mendapatkan pembelajaran melalui model pembelajaran ekspositori. Data yang dikumpulkan akan dianalisis menggunakan metode statistik ANOVA 2 jalur. Hasil penelitian menunjukkan bahwa: 1) Terdapat perbedaan yang signifikan dalam kemampuan komunikasi matematis siswa antara kelompok yang diajarkan melalui model PBL dan kelompok yang diajarkan melalui model pembelajaran ekspositori. 2) Tidak terdapat interaksi yang signifikan antara model pembelajaran dan kemampuan awal matematika siswa terhadap kemampuan komunikasi matematis siswa. Artinya, pengaruh model pembelajaran terhadap kemampuan komunikasi matematis siswa tidak dipengaruhi oleh kemampuan awal matematika mereka. Dengan demikian, hasil penelitian ini menunjukkan bahwa model PBL memiliki dampak positif terhadap kemampuan komunikasi matematis siswa dan dapat menjadi pilihan yang efektif dalam meningkatkan kemampuan komunikasi matematis dalam konteks pembelajaran matematika.
The Research on the Relationship Between Adolescents' Use of Information Technologies and Their Psychological Needs in Terms of Self-Determination Theory
Authors: KABA İlker
Published: October 2023

In this study, it was examined whether there is a relationship between adolescents' information technology use and basic psychological needs levels with some demographic characteristics of adolescents and their frequency of social media use. In addition, it was aimed to determine whether adolescents' basic psychological needs predict their use of technology. In this study, relational survey model, one of the quantitative research techniques, was used. Personal Information Form (PIF), Information Technology Use Scale (ITUS) and Need Satisfaction Scale (NSS) were used in the study. The data were collected from 508 adolescents in secondary education institutions in Mamak and Çubuk districts of Ankara province and Tarsus and Yenişehir districts of Mersin province during the 2019-2020 academic year. The relationship between the average scores of the adolescents on the NSS and the ITUS and their ages, number of siblings and grade point averages were analysed. Significant positive and negative relationships were found between the social networks used by adolescents (Facebook, Twitter, Instagram, Youtube, LinkedIn, Snapchat, Tiktok, WhatsApp), basic psychological needs and information technology use. It was determined that the scores obtained from the Information Technologies Usage Scale were predicted by age and basic psychological needs.
THE HOUSES OF ADHR’AAT AND THEIR SCIENTIFIC AND ADMINISTRATIVE CONTRIBUTIONS IN THE LEVANT AND EGYPT FROM THE SEVENTH CENTURY TO THE NINTH CENTURY AH
Authors: Salim AWAD Riad
Published: October 2023

The corridors of science and administration in the Levant and Egypt during the period from the seventh century until the ninth century AH witnessed a remarkable presence of the scholars of Adhr’aat city, as they contributed to the support and development of religious sciences such as the sciences of the Noble Qur’an, the hadith, and jurisprudence, as well as the sciences of the Arabic language, including grammar and literature, they taught it in some schools in the Levant and Egypt, in addition to authoring books, especially in the field of jurisprudence, and their administrative contributions were represented in their leadership of important functions in the state such as the judiciary, the ministry, the Hesba, and the consideration of the army and others, and the reason for choosing the subject of study is to strive to achieve several goals, including shedding light on the name and history of the city of Adhr’aat, that many researchers may not have heard of it, and getting to know the most important scientific and administrative families that emerged from it, and knowing the scientific and administrative contributions of these families in the Levant and Egypt during the period the focus of the research, as well as knowing the role of the ruling authority in supporting the houses of Adhr’aat in a way that enhances their value or position within the Levantine and Egyptian societies.
THE DYNAMICS OF SOCIAL NORMS AND VALUES AMONG EDUCATED RURAL YOUTH A SOCIOLOGICAL STUDY IN THE FIELD OF THE ZAYAN TRIBES IN THE PROVINCE OF KHENIFRA AS A CASE STUDY
Authors: ASSAFAH Said
Published: October 2023

This study seeks to investigate the dynamism defined by social norms and values among educated rural youth in the Moroccan Middle Atlas because we belong to this rural milieu and this field is still a fertile field for sociological research. We relied on the qualitative approach in collecting data, where we depended on the semidirected interview and observation with participation as tools for collecting field data. As for the approach that we followed in the analysis, we have adopted the scientific approach of Max Weber as it helps us understand the meanings and indications behind the actions and attitudes of the actors within the studied community. The basic conclusions that we can draw are that in rural area, despite the development it has recently witnessed, we cannot definitely talk about a transition from one situation to another, but rather there is continuity of some customs within modern institutions, and therefore the change that occurs to social and cultural structures is not a radical change, but rather a superficial change. Also, although the rural areas have been invaded by the new socialization agents (school, media and civil society associations), they could not eliminate the role of the traditional socialization agents such as the nuclear and the extended family, as most of the behavioral values still derive their ingredients from the family framework such as obedience, compliance, defect, forbidden, discontent and contentment. These values govern man's relationship with women and the relationship between young and old