bluuebunny/crossref_metadata_2025 huggingface dataset:
Peranan Pelatihan, Lingkungan Kerja dan Kompensasi terhadap Kinerja Karyawan
Authors: Adriyanto Yusup , Qodariah Qodariah
Published: October 2022

Tujuan Penelitian ini adalah agar penulis mendapatkan gambaran apakah Peranan Pelatihan, Lingkungan Kerja dan Kompensasi yang ada di PT. Sanken Argadwija mempengaruhi terhadap Kinerja Karyawannya. Harapannya dengan  penelitian ini perusahaan bisa menetapkan strategi untuk memperbaiki kondisi perusahaan dan dapat meningkatkan kinerja karyawannya. Perusahaan bisa juga mengambil tindakan yang kompetitif untuk selalu berusaha dalam meningkatkan kinerja karyawannya secara lebih berkelanjutan. Metode penelitian yang digunakan dengan pendekatan deskriptif kualitatif, teknik pengumpulan data dengan observasi, wawancara dan dokumentasi. Teknik analisis data menggunakan model analisis interaktif Miles dan Huberman, yaitu reduksi data, penyajian data dan penarikan kesimpulan atau verifikasi. Hasil penelitian menunjukkan bahwa Pendidikan / latihan kerja,  perbaikan cara kerja,  upah /gaji sesuai bobot dan prestasi kerja,  perbaikan lingkungan , kondisi kerja  dan  motivasi sangat mempengaruhi tingkat produktivitas karyawan. Faktor manusia yang  terdiri atas faktor: Pelatihan, kepemimpinan, tingkat upah pekerja, kepuasan kerja, insentif, pembagian keuntungan, hubungan kerja antar sejawat, kemangkiran juga sangat menentukan dalam kinerja karyawan.
Caracterización del perfil de las mujeres con diagnóstico de Diabetes Mellitus Gestacional
Authors: Martínez-Lara Verónica , Morales-Ramírez Dionicio , Sánchez-Hernández Norma A. , Eusebi-González Andrea P.
Published: October 2022

Objetivo: Identificar el perfil de las mujeres con diagnóstico de Diabetes Mellitus Gestacional en una unidad de atención primaria ubicada en Ciudad Madero, Tamaulipas, México. Método: Estudio descriptivo, observacional, retrospectivo y transversal. Se recogió información del expediente clínico sobre los antecedentes personales patológicos, familiares y gineco obstétricos de un total de 156 mujeres embarazadas diagnosticadas con DMG. Además, se identificó el estado nutricional pregestacional con el índice de masa corporal y la ganancia de peso hasta el momento del diagnóstico. Resultados: La edad promedio de las mujeres fue de 31 años, el 42.3% cuenta con escolaridad media superior y el 49.4% vive en unión libre. El 87.2% de ellas, presenta problemas de obesidad y sobrepeso previo al embarazo. Al momento del diagnóstico de DMG, el 97.4% presentó sobrepeso y obesidad. La ganancia de peso que presentaron las mujeres fue de 6.03 kilogramos en promedio. Conclusiones: El estado nutricional que presentan las mujeres embarazadas de la unidad de atención primaria no es adecuado. Lo cual, representa un riesgo latente para el desarrollo de DMG. Por ello, es necesario reforzar el mensaje sobre la práctica de una calidad de vida saludable antes, durante y posterior al embarazo desde la atención primaria.
PERFORMANCE AUDIT’S PERCEIVED CONCEPT AND ROLE EXPECTATION: IS IT CONFORMITY OR CONFLICT?
Authors: SPAMA Diandra Talita , JATİNİNGSİH Dyah Ekaari Sekar
Published: October 2022

Extant accounting literature has broadly investigated expectation gap in audit context. Previous research reveals the existence of conflict which refer to role concept whether in the expectation of auditor role, response to audit output, or understanding of auditee’s business process. Meanwhile, observation from internal organization’s point of view is still limited whereas the urgency of evaluating performance and maintaining organizational excellence are escalating. Examining performance audit in service organization, this study qualitatively observed perception and expectation of stakeholders on performance audit concept using role theory framework. Role theory posits some propositions in relation to patterns of behavior to which individuals can be in conformity or can be in conflict in terms of compatibility to expectation of others. Semi structured interview with participant’s observer is performed in this study to investigate key stakeholders in the organization. Interesting result emerges which shows the existence of practicality concept instead of conformity. In addition, expectation of such impact from performance evaluation is equally the same among different stakeholders except on the perceived quantity measure. Important implication of this study result is further discussed.
Assessment of artists’ socioeconomic and working conditions: the empirical case of Lithuania
Authors: KREGZDAİTE Rusne
Published: October 2022

The main aim of this research is to explore existing methodologies for artists’ labour force and create artists’ socio-economic and creative conditions an assessment model. Artists have a dual aims in their creative working process: 1) income, and 2) artistic self-expression. The valuation of their conditions takes into consideration both sides: the factors related to income and the satisfaction for creative process and its result. The problem addressed in the study: tangible and intangible artists' criteria used for assessments creativity conditions.

The proposed model includes objective factors (working time, income, etc.) and subjective factors (salary covering essential needs, self-satisfaction). Other intangible indicators taken into account: the impact on the common culture, social values, and the possibility to receive awards, to represent the country in the international market. The empirical model consists of 59 separate indicators, grouped into eight categories. The deviation of each indicator from the general evaluation allows identifying the strongest and the weakest components of artists’ conditions.
VİRAL PAZARLAMANIN DİJİTAL DÜNYADA SATIN ALMA DAVRANIŞLARINA ETKİSİ: K KUŞAĞI ÜZERİNE BİR İNCELEME
Authors: ÇELİK VAROL Merve , VAROL Erdem , TÜZEL URALTAŞ Kıvanç Nazlım
Published: October 2022

Bu çalışmanın odak noktası viral pazarlama ve çevrimiçi alışveriş ekseninde 1995-2002 yılları arasında doğan “K kuşağı”nın satın alma davranışlarına ışık tutmaktır. Bu amaçtan hareketle söz konusu çalışmada survey yöntemi kullanılmış ve K kuşağında yer alan 332 bireye çevrimiçi anket formu uygulanmıştır. Araştırmadan ortaya çıkan veriler SPSS Windows 22.0 programı kullanılarak analiz edilmiştir. Araştırmada, K kuşağında yer alan kadın bireylerin erkeklere oranla daha fazla çevrimiçi alışveriş tutum ve davranışı gösterdiği, haneye giren gelir miktarı arttıkça viral pazarlama ve çevrimiçi alışveriş tutum ve davranış oranının arttığı, benzer biçimde lisans mezunu olan bireylerin diğer eğitim durumlarına göre daha fazla viral pazarlama ve çevrimiçi alışveriş tutum ve davranışı gösterdiği sonuçlarına ulaşılmıştır. Ayrıca söz konusu çalışmada K kuşağının çevrimiçi alışveriş tutum ve davranışları ile viral pazarlama arasındaki ilişkinin pozitif yönlü zayıf bir ilişki olduğu sonucuna ulaşılmıştır.
Comparative evaluation of the genotoxicity of carbendazim technical grade active ingredients in the Ames test and micronucleus in vivo test
Authors: Egorova Olga Valerevna , Averyanova Natalia Sergeevna , Kara Liliya Alexandrovna , Ilyushina Natalya Alexandrovna
Published: October 2022

Introduction. Carbendazim is a systemic benzimidazole fungicide used against a wide range of crop diseases. The ability of carbendazim to induce the incidence of chromosomal aberrations and micronuclei in mammalian cells by influencing the processes of mitotic spindle formation in the cell cycle have been shown in various in vitro and in vivo tests. Contradictory data were obtained in the bacterial test system Salmonella/microsomes, indicating both the absence and the presence of mutagenic activity of carbendazim. The discrepancy in the results may stem from the presence of impurities. The aim of the study was a comparative evaluation of the genotoxicity of various technical products of carbendazim. Materials and methods. The genotoxicity of carbendazim was studied using the plate incorporation version of the Ames test on 5 strains of Salmonella typhimurium in the presence and the absence of metabolic activation system (+S9/-S9) and in a micronucleus test in CD-1 mice. Two technical grade active ingredients (TGAI) and an analytical standard for carbendazim were tested. Results. In the Ames test, the analytical standard of carbendazim possessed no mutagenic activity (±S9) on any of the strains. The most pronounced mutagenic effect was observed for the TGAI I in TA98 strain, the number of revertants at the maximum concentration was 5-7 times higher than that in the negative control. The positive effects of carbendazim TGAIs in the Ames test are likely mediated by the presence of impurities. Under in vivo conditions, all tested TGAIs of carbendazim induced a statistically significant and dose-dependent formation of micronuclei in polychromatic erythrocytes (PCE) of mouse bone marrow. The mean frequency of PCE with micronuclei at the maximum dose exceeded this rate in the negative control by 21-24 times. Research limitations. The study is limited to testing the mutagenic activity of two samples of carbendazim technical products and one sample of its analytical standard in both in vivo and in vitro tests. Conclusion. Taking into account the high content of the active substance in the tested TGAIs, the bacterial reverse mutation test is a highly sensitive method for assessment of the equivalence of carbendazim generic products. The use of a micronucleus test for evaluating of the equivalence of carbendazim TGAIs to the original substance is inappropriate due to the pronounced aneugenic effect.
Toxicometabolomics — integration of preventive and analytical toxicology
Authors: Radilov Andrey Stanislavovich , Ukolov Anton Igorevich
Published: October 2022

Introduction. This paper considers aspects of the development of a toxicokinetically based model for scaling the limit concentrations of toxic compounds in the air, estimating the coefficients of their material cumulation, as well as estimating the concentrations of toxicants in biological media expected in the course of biological control. The results of testing the model on the example of organophosphorus pesticides (OP) and volatile industrial pollutants (VIP) are presented. Material and methods. For experimental modeling of intoxication, male chinchilla rabbits obtained from the Rappolovo nursery were used. Blood sampling was carried out from the marginal vein of the ear. For the highly sensitive determination of OP and VIP in biological samples, previously developed highly sensitive gas chromatographic techniques were used. Calculation of toxicokinetic parameters was made using a two-compartment model. Results. A toxicokinetically based model for scaling the limit concentrations of toxic compounds in the air, estimating the coefficients of their material cumulation, and estimating the concentrations of toxicants in biological media expected in the course of biological control is proposed. Research limitations. The proposed algorithm for scaling toxicokinetic parameters can be applied under the condition that the bioavailability of chemical compounds for the animal and human body is close, as well as the area under the toxicokinetic curve that is close to a linear dependence on the dose. Conclusion. Using the proposed toxicokinetically substantiated model for scaling the threshold concentrations, recommendations were made on chemical-analytical methods of biological control in the working area and atmospheric air for OP and VIP.
The effect of the combined effects of carbon monoxide and harmful physical factors on the behavioral activity of animals
Authors: Kriyt Vladimir Evgenevich , Reinyuk Vladimir Leonidovich , Sladkova Yuliya Nikolaevna , Pyatibrat Alexandr Olegovich)
Published: October 2022

Introduction. In the course of their work, firefighters are exposed to many harmful and dangerous factors, among which the chemical factor takes the leading place. Carbon monoxide is an integral part of any combustion, and its leading role in the toxic effect of combustion products is confirmed by numerous experimental data. The results obtained in the experiment on animals are of great importance in the study of combined effects. The purpose of the study was to study the behavioral activity of animals under combined exposure to carbon monoxide and harmful physical factors. Material and methods. The study was performed on outbred white male rats 3 months of age, in two directions: the study of the combined effects of carbon monoxide and elevated air temperature and the study of the combined effects of carbon monoxide and vibroacoustic factor. In each of the experimental models, rats were randomly divided into 6 groups: the first group was exposed to a single physical factor under study, the second group was exposed to multiple physical factors (for 14 days), the third group was exposed to a single exposure to carbon monoxide, the fourth group was exposed to multiple exposures to monoxide carbon, the fifth group was subjected to a single combined effect of a physical factor and carbon monoxide; the sixth group was subjected to multiple combined effects of the physical factor and carbon monoxide. The study of the behavioral activity of animals was carried out using the “Open field” and “Elevated plus maze” methods. Results. The data obtained indicate that the combined effect of carbon monoxide and harmful physical factors causes a change in the indicators of behavioral reactions of animals, while if with a single exposure most of the indicators return to the background values in a day, then with repeated exposure they remain significantly changed. Conclusion. The data obtained can be applied in studying the long-term effects of the combined effects of carbon monoxide and harmful physical factors on the body of firefighters.
The use of neurotoxins in fundamental, medical and biological sciences on the example of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Authors: Safandeev Vitalij Vasilevich , Sinitskaya Tat’yana Alekseevna
Published: October 2022

Introduction. Neurotoxins are a class of chemicals that damage neurons. Some pesticides have a similar effect. The increase in areas with developed heavy industry and agriculture, uncontrolled use of pesticides contribute to the emergence and progression of Alzheimer’s and Parkinson’s disease (PD). The insidiousness of PD is that it is still incurable, since there is no early diagnosis: for decades it has been asymptomatic, and by the time of manifestation there are no target neurons for therapy. Considering that the diagnosis is made at the late stages of PD development, the treatment of the disease is ineffective. It follows that in order to increase the effectiveness of treatment, it should be started as early as possible - before the appearance of motor symptoms, at the preclinical stage. To do this, it is first necessary to develop an early (preclinical) diagnosis of PD based on an in-depth study of the cellular and molecular mechanisms of pathogenesis. In order to develop early diagnosis and preventive therapy of PD, proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was used in this study. Material and methods. To simulate the preclinical and clinical stages of PD, inbred lines of animals were injected with MPTP according to certain schemes. The behavior of experimental animals was assessed, and after their decapitation, the content of monoamines in the structures of the brain, peripheral organs, and blood plasma was determined by HPLC, and a morphofunctional analysis of the studied tissues and organs was performed. Results. The clinical stage of PD was modeled in animals, which corresponds to the key characteristics of PD in humans. A hypothetical preclinical stage of PD was modeled in animals, on which the method of early diagnosis was successfully tested. This model shows a number of important biochemical changes in peripheral organs, indicating the systemic nature of the disease and preceding the onset of the clinical stage of PD. Research limitations. The results of this study can only be applied to humans only after similar results have been obtained in monkeys. Limitations. Only after obtaining similar results in monkeys the results of this study can be translated to humans. Conclusion. Knowledge about the mechanisms of action of some neurotoxins is expanding, which are successfully used for the needs of fundamental, medical and biological sciences.
Methods of biodiagnostics in aquatic ecotoxicology
Authors: Chuiko Grigorii Mikhailovich , Tomilina Irina Ivanovna , Kholmogorova Nadezda Vladimirovna
Published: October 2022

Introduction. Modern ecotoxicology for the detection, quantitative and qualitative assessment of the content of toxicants in the environment and living organisms uses the entire spectrum of chemical-analytical methods. However, methods of biodiagnostics are specific to this science. Materials and methods. The paper summarizes information on the use of modern methods of biodiagnostics in aquatic ecotoxicology: biomarking, biotesting and bioindication. Results. The main advantage of biodiagnostics over physicochemical methods of analysis is the ability to identify the biological consequences of the action of a single stress factor or their combination. At the same time, biodiagnostic methods allow fixing the additivity, antagonism and synergy of their joint action. Biomarking differs from other biodiagnostic methods in response time from several minutes to several days, high sensitivity and sufficient specificity, since it gives the ability to register the changes occurring in the biological system at the early stages of the action of factors at their low intensity and at the same time identify the nature of the stress factor. Biotesting has a slower response time than biomarking (from several hours to several weeks), but the ecological significance at the level of an individual is more obvious: the death of an organism, a decrease in reproductive ability up to the cessation of reproduction, disruption of growth, development, various types of behavior, etc. Bioindication is characterized by a sufficiently long-time delay of responses of supraorganismal biosystems to the action of a stress factor from several weeks to several years. At the same time, it makes possible assess more adequately and reliably the changes that have occurred over a long period of timeof stress factor action in order to predict options for the further development of ecosystems. Limitations. Methods of biodiagnostics in aquatic ecotoxicology have no restrictions on their use. However, unlike the methods of physicochemical analysis, they do not allow a quantitative, and sometimes a qualitative assessment of the stress factor. Therefore, they should be used in conjunction with the methods of qualitative and quantitative physicochemical analysis. Conclusion. Thus, the biodiagnostic approach, including biomarking, biotesting, and bioindication, together with physics and chemicals analysis plays an important role in the modern integrated system for assessing the ecological state of water bodies and anthropogenic impact on them.
Revisiting Navarro et al.: A Double Tilt View- Students’ Satisfaction with Professional Accounting Education
Authors: Nagendrakumar Nagalingam , Madhavika Naduni , Nadishan Yuresh , Ameen Zakiya , Kulatunga Kasuni , Perera Anuththara , Perera Chamika
Published: October 2022

The purpose of this study is to investigate the issue of why a significant gap exists between the number of students enrolled and the number of students who pass out as professional accountants taking Navarro et al. (2005) model as the theoretical lens. The study adopted a deductive approach, stratified random sampling, and distributed 500 questionnaires. The response rate was 80%. The study found that the course assessment and institutional image, teaching methods, teaching staff, course organisation and infrastructure facilities, and institutional administration, and efficiency significantly impact the student satisfaction. Next tilt argues that the students’ satisfaction significantly impacts the students’ loyalty. Also, the study extends Navarro et. al.’s model by adding two more constructs viz. commitment as alumni and commitment as a student. The findings have practical implications for Professional Accounting Education Institutions (PAEIs) which seek to retain their students. The students’ needs and the students’ loyalty are the two tilt of students’ satisfaction which lower students’ intentions to leave by nurturing their expectations met by the PAEIs.
Effect of Teaching and Learning Approaches on Graduates’ Entrepreneurial Competency for Self-Employment in Tanzania
Authors: Chengula Isaac  J , Bengesi Kenneth M K , Komba Sotco C , Mvena Zebedayo S K
Published: October 2022

Purpose: Over the past decade, the need for improved teaching and learning approaches that enhance entrepreneurial competencies has been a critical agenda in Tanzania. Despite its importance, the process of realizing entrepreneurial competencies through education, suffers from various shortcomings especially in relation to teaching and learning approaches. This paper assesses the effects of teaching and learning approaches on graduates’ entrepreneurial competencies for self-employment in Tanzania.

Methodology: The study used a cross-sectional case study research design with the aid of snowball sampling. A sample of 202 respondents was picked from selected universities of Sokoine and St. Augustine of Tanzania. Data were collected using a structured questionnaire which included a Likert scale, key informant interviews and documentary reviews. While content analysis was used to analyze qualitative data, statistical package for social sciences (SPSS) was used to analyze quantitative data.

Findings: The results showed that a theoretical active participation approach (with the mean 3.8614) was used to develop capacity that empowered graduates with entrepreneurial competencies indicating a shift from rote learning that previous studies established. Most of the practical teaching and learning approaches ascribing to entrepreneurial framework were, however, not applied to yield greater effect on graduates’ self-employment. Based on the results, the paper concludes that universities used only fragments of a student-centered approach as opposed to incorporating the holistic approach recommended for educating for entrepreneurship.

Recommendations: The paper recommends that university instructors should apply holistic teaching and learning approaches that would increase graduates’ confidence and commitment to seek self-employment in Tanzania.
ENTREPRENEURIAL ORIENTATION AND MEDICATION THERAPY MANAGEMENT SERVICES DELIVERY OF COMMUNITY PHARMACIES IN RIVERS STATE, NIGERIA.
Authors: Alagala M B , Bagbi B M , Mgbahurike A A
Published: October 2022

Purpose: This study examined the relationship between entrepreneurial orientation and medication therapy management services delivery of community pharmacies in Rivers State, Nigeria.

Methodology: Correlational research design was adopted for the study using the survey method. All community pharmacies in Rivers State registered with the Pharmacists Council of Nigerian (PCN) constituted the population of the study and the study had a population of 462 from which a sample size of 214 community pharmacies was determined. The sampling unit of the study were superintendent pharmacists of the community pharmacies. Primary data were collected using a well-structured questionnaire whose reliability tested on the Cronbach Alpha scale using SPSS version 24.0 was 0.810. Regression analysis was used to test the hypotheses.

Results: The findings of the study showed that there was a positive and significant relationship between risk taking propensity and medication therapy management services delivery of community pharmacies in Rivers State, Nigeria with R value of 0.915 at p<0.05. The correlation between proactiveness and the delivery of medication therapy management was positive and significant with R value of 0.894 at p-value <0.05 while the correlation between innovativeness and competitive aggressiveness and medication therapy management services delivery was also positive and significant with R values of 0.899 and 0.916 respectively at p-values <0.05.

Conclusion: Based on the research findings, the study thus concluded that entrepreneurial orientation (risk-taking propensity, pro-activeness, innovativeness, and competitive aggressiveness) can be considered a potent factor in the sustained delivery of medication therapy management services of community pharmacies.

Recommendation: The study recommended amongst others that Community pharmacies/pharmacists in Rivers State should improve in their innovativeness by delivering quality cognitive services.
REVIEW ON OINTMENT
Authors: Kaushal Dev , Upadhyaya Nikita
Published: October 2022

Ointments are semisolid dosage form which usually act as visco-elastic materials when shear stress is applied. They generally contain medicinal ingredients and are used to be applied externally to the body for therapeutic effect. Many therapeutic agents used for topical application to intact or broken skin or to mucous membranes are presented in the form of semisolid consistency variously designated as ointments, creams, pastes etc. It is used mainly as protective or emollient for the skin. The first step towards the goal is screening of plants used in popular medicine. Along with other dosage forms, herbal drugs also used in the form of ointment.
The Effect of Hatha Yoga on Stress, Life Satisfaction and Quality of Life in Nursing Students
Authors: SEKİ ÖZ Hilal , CİRİŞ Vahit
Published: October 2022

The ultimate goal of yoga is to achieve peace by providing unity in mind and spirit. Therefore, it offers important opportunities to improve stress management and quality of life. This quasi-experimental study with pretest-posttest control group design aims to examine the effects of eight weeks of Hatha yoga on stress, life satisfaction and quality of life in nursing students. A total of 40 nursing students, including 22 in the experimental group and 18 in the control group, participated in the study. The data were collected using a descriptive information form, the Depression Anxiety Stress Scales (DASS-21), the Satisfaction with Life Scale (SWLS), and the 12-Item Short Form Health Survey (SF-12). Fisher's exact test was used to compare the descriptive characteristics of those in the experimental and control groups, and the Wilcoxon signed-rank test to compare the pre- and post-test results. After Hatha yoga, the stress scores of nursing students in the experimental group decreased significantly (p=0.001), and their life satisfaction scores (p=0.006), physical dimension of quality-of-life scores (p=0.014), and mental dimension of quality-of-life scores (p=0.012) increased significantly. However, there was no significant difference for those in the control group during the same period (p>0.050). These results suggest that Hatha yoga is an effective method to improve stress management, life satisfaction and quality of life among nursing students. It is recommended to conduct further studies with larger samples, including follow-up measurements.
Collection of endemic actinomycetes capable of degrading Lindane in order to produce biological products for the treatment of pesticide pollution toward safe agricultural production
Authors: Luu Tran Dong , Vu Son Tung , Vu Ha Phuong , Hoang Quynh Anh , Tran Thi Quynh Trang , Nguyen Thi Yen , Nguyen Hong Minh , Tran Thi Thanh Huyen , Nguyen Kim Nu Thao , Pham The Hai ,   GREENLAB, Center for life science research (CELIFE),   GREENLAB, Center for life science research (CELIFE),,   GREENLAB, Center for life science research (CELIFE),   GREENLAB, Center for life science research (CELIFE),   GREENLAB, Center for life science research (CELIFE),   GREENLAB, Center for life science research (CELIFE),   Bioresource Research Center, Phenikaa University,   Department of Microbiology,   Department of Cell Biology, Faculty of Biology, Hanoi University of science, Vietnam national university, Ha Noi, Viet Nam,   GREENLAB, Center for life science research (CELIFE); Department of Microbiology
Published: October 2022

Pesticide residues in the soil are a huge threat to agriculture. ɤ- hexachlorocyclohexan (Lindane or isomer ɤ -HCH) is one of the pesticides widely used in agriculture after 1945. Due to the harmful effects on health of Lindane, UNEP (United Nations Environment) Program - United Nations Environment Program) decided to stop the pollution of Lindane worldwide in 2005. However, with a long half-life, it is very difficult to control residual Lindane in soils. The purpose of this study is to isolate and select actinomycete strains capable of degrading Lindane in order to develop a biological product that can remove residual Lindane in agricultural soil in a safe and environmental-friendly manner. Basic actinomycete isolation methods have been applied in combination with a number of oriented isolation methods to evaluate the growth ability of actinomycetes on media with and without Lindane. The ability to degrade Lindane of actinomycetes was also evaluated based on the rate of chloride ion removal in the substrate. The remarkable actinomycetes were then studied for biological characteristics such as morphology, biochemical and physiological properties, and some metabolic activities related to the degradation of Lindane. We obtained 9 actinomycetes capable of decomposing Lindane isolated from soil samples in farms in Nghe An. Among them, the two strains A119 and LD02 belonging to the genus Streptomyces displayed the best Lindane degradation performance based on their chloride ion removals. They were further studied for their biological characteristics and eventually identified.  
Evaluation of safety criteria for the total amount of volatiles in foam food containers in Ho Chi Minh City
Authors: Bui Thi Kieu Anh , Le Thi Kim Hong , Nguyen Doan Diem Ngoc , Lam Tran Van Anh , Le Thi Ngoc Hanh ,   Department of Nutrition and Food Safety, Institute of Public Health Ho Chi Minh City,   Department of Nutrition and Food Safety, Institute of Public Health Ho Chi Minh City,   Department of Testing, Institute of Public Health Ho Chi Minh City,   Department of Testing, Institute of Public Health Ho Chi Minh City,   Department of Testing, Institute of Public Health Ho Chi Minh City
Published: October 2022

Disposable plastic utensils such as plastic boxes and foam boxes are becoming more and more popular with significant output in Vietnam. These products are mainly made from polystyrene, which should be strictly controlled to reduce the risk of food insecurity, due to the leaching of certain substances into food. Therefore, conducting a study to determine the toxic substances remaining in the styrofoam box is necessary, with objective is to determine the percentage of foam food container products with total volatiles (through the determination of substances: styrene, ethylbenzene, toluene, n-propylbenzene) exceeding the allowable limit according to QCVN 12-1:2011/BYT. The study conducted on 138 samples of foam boxes randomly collected at 46 markets in 23 districts in Ho Chi Minh City, with analytical method being GC-MS technical method for the determination of volatile compounds from foam boxes. Results showed that all 138 foam samples had amount of each styrene, ethylbenzene below 1 mg/g, total styrene and ethylbenzene less than 1 mg/g, total volatiles (styrene, toluene, ethylbenzene, n-propylbenzene) are all below 5 mg/g. Conclusion: There should be stricter control regulations on the quality of disposable food containers and the use of foam boxes should be limited to reduce the impact on the environment.  
Source of food in the kitchencollectives of enterprises, schools with domestic investment capital ingredients - Hung Yen province in 2019
Authors: Do Manh Hung , Nguyen Thanh Long ,   Hung Yen Provincial Department of Food Safety and Hygiene,   Hung Yen Provincial Department of Food Safety and Hygiene
Published: October 2022

A cross-sectional study was conducted to evaluate the current status of food ingredients in the collective kitchens of businesses and schools with domestic capital in Hung Yen province in 2019. The results of the study showed that the amount of leafy vegetables, root vegetables, fruit and aquatic products purchased at the production unit determined to have a certificate of eligibility for the establishment or other equivalent papers accounts for a small proportion of 1.9%, 0.9%, 0.9%, 0.4%, respectively. 01% of vegetable and fruit providers, 41.9% of rice millers and 1.5% of aquaculture providers have certificates of eligibility for food safety or other documents. Most of the remaining raw materials were purchased from small-scale, household-scale production households that do not have a certificate of eligibility for food safety or other equivalent papers. Based on the obtained results, the research team proposes to the Provincial People's Committee to have a policy to expand the models of safe vegetable growing to meet the needs of collective kitchens as well as people in the province. Collective kitchens, especially large-scale kitchens with a large concentration of workers, need to increase the purchase of raw materials for vegetables, tubers and fruits at production facilities that have been certified to meet food safety conditions, VietGAP.  
Determination of glucosamine in dietary supplement samples by capillary electrophoresis using capacitively coupled contactless conductivity detector (CE-C4D)
Authors: Dang Thi Huyen My , Nguyen Thi Ngoc Ly , Do Yen Nhi , Dinh Thi Diu , Kieu Thi Lan Phuong , Hoang Quoc Anh , Pham Hoang Nguyen , Pham Thi Quynh , Tran Cao Son , Nguyen Thi Minh Thu , Nguyen Quang Huy , Nguyen Thi Anh Huong ,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Faculty of Environmental Science, University of Science, Vietnam National University, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   Poison Control Center, Bach Mai Hospital, Hanoi, Vietnam,   Poison Control Center, Bach Mai Hospital, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam,   University of Medicine and Pharmacy, Thai Nguyen University, Thai Nguyen, Vietnam,   Faculty of Chemistry, University of Science, Vietnam National University, Hanoi, Vietnam
Published: October 2022

The quantification of glucosamine in dietary supplements was investigated by using capillary with capacitively coupled contactless conductivity detection (CE-C4D). Optimal conditions included electrophoresis buffer solution 10 mM Tris/Ace; pH = 5,0; sample injection height 25 cm; sample injection time 30 s; separation voltage 20 kV. The limit of detection (LOD) and the limit of quantification (LOQ) of glucosamine were 8.00 ppm and 26.67 ppm, respectively. Calibration curve was constructed over the range from 20 to 1000 ppm giving a good linear correlation coefficient (R2 = 0.9993). The relative standard deviation (RSD) ranged from 1.28% to 2.33% (n = 3) and the recovery efficiency ranged from 95.2 to 102.3% which indicated good precision and trueness of our method. The method was applied to determine glucosamine in 4 dietary supplement samples randomly collected at the local markets. The CE-C4D results were compared with those obtained by reference HPLC-FLD method, showing good agreement between the two methods (relative error < 15%).
Food chemical contamination condition in Lac Thuy district, Hoa Binh province surveillance in 2021
Authors: Nguyen Thanh Hieu , Ninh Thi Nhung , Pham Thi Kieu Chinh ,   Lac Thuy District Medical Center,   Thai Binh University of Medicine and Pharmacy,   Thai Binh University of Medicine and Pharmacy
Published: October 2022

Pesticides, formol, borax, and unpermitted colorants using in food production chain still need to control in Vietnam. Our study aimed to determine the chemical contamination in some common food samples collected at production facilities, business stores, wholesale food supply markets in Lac Thuy district. As the results, borax detected at the ratio of 15.9%, in which "Cha" accounted for the highest rate of 25%, " gio lon" was 21.4%; the lowest rate was vermicelli 7.7% and noodle soup 8.3%. The ratio of alkaline dye contaminated was quite high at 58.5%; in which sausages and melon seeds accounted for the highest proportion of over 80%, and the lowest was “Su Se” cake and “Com” cake with 33.3%. Formol was detected at 24.3%, in which rice noodle and vermicelli detected over 30%. The ratio of pesticide residues in fruits and vegetables was 35.6%, in which beans and pulses was contaminated highest ratio with 60%, following is vegetables with 55%, and tomatoes and lettuce with lowest ratio of over 10%.
Validation of a PCR method for the detection Campylobacter spp. in milk powder
Authors: Nguyen Do Phuc , Nguyen Ly Hoang Ngan , Le Thi Hien , Ngo Thanh Phong , Tran Bao Tram , Nguyen Ngoc Thanh Hien , Nguyen Thi Thanh Truc , Hoang Hoai Phuong ,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City,   Institute of Public Health Ho Chi Minh City
Published: October 2022

An alternative PCR method for rapid detection of Campylobacter spp. in milk powder was validated according to TCVN 12365-2:2018 (ISO 16140-2:2016). In this study, performed with paired study, validation examines the following parameters: (1) sensitivity (sensitivity for the alternative method: SEalt, sensitivity for the reference method: SEref, relative trueness: RT, false positive ratio for the alternative method: FPR), (2) relative level of detection (RLOD) and (3) inclusivity and exclusivity. The result showed that: sensitivity for the alternative method: 85.7%, sensitivity for the reference method 92.8%, relative trueness: 85%, false positive ratio for the alternative method: 16.7%, relative level of detection: 0,859 CFU/25g. For inclusitivity testing, two reference strains were detected. For exclusitivity testing, all of 20 strains were not detected. All the parameters tested were met according to TCVN 12365-2:2018 (ISO 16140-2: 2016) requirements.
Determination of adenosine and cordycepin in dietary supplements circulating on the Hanoi market
Authors: Nguyen Thanh Dat , Nguyen Thi Hong Hanh , Dam Thi Thu , Nguyen Van Hieu , Lai Thi Phuong , Duong The Bac ,   Hanoi Drugs, Cosmetics, Food Quality Control Center,   Hanoi Drugs, Cosmetics, Food Quality Control Center, Hanoi, Vietnam,   Hanoi Drugs, Cosmetics, Food Quality Control Center, Hanoi, Vietnam,   Hanoi Drugs, Cosmetics, Food Quality Control Center,   Hanoi Drugs, Cosmetics, Food Quality Control Center,   Hanoi Drugs, Cosmetics, Food Quality Control Center
Published: October 2022

High performance liquid chromatography with diode-array detector (HPLC-DAD) has been fully validated according to AOAC requirements for the determination of adenosine and cordycepin in dietary supplements containing Cordyceps. Chromatographic conditions using InertSustain C18 (250 mm × 4.6 mm; 5 µm) column, with gradient program composed of methanol and water eluted in 35 min, diode-array detector at 260 nm, flow rate of 1.0 mL/min. The study has determined the content of adenosine and cordycepin in 24 dietary supplement samples containing Cordyceps in different dosage forms circulating on the Hanoi market. The results showed that the contents of the two substances studied in the samples fluctuated greatly (adenosine from 28.19 - 956.3 µg/g with solid and oily form, from 1.26 - 25.31 µg/mL with the liquid form; cordycepin from 5.25 - 1287 µg/g with solid and oily form, from 1.91 - 32.38 µg/mL with liquid form), especially one sample was detected without both adenosine and cordycepin, one sample did not have adenosine.  
Validation of methods for determination of lead and cadmium content in butterfly pea flowers (Clitoria ternatea) in the Cai Rang district, Can Tho city by atomic absorption Spectrophotometer AAS
Authors: Nguyen Kim Dong , Pham Huyen Trang , Nguyen Van Ba , Ha Phuong Thao , Vo Thi Kien Hao , Le Nguyen Tuong Vi ,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam,   Department of Applied Biology, Tay Do University, Can Tho, Vietnam
Published: October 2022

The content of cadmium (Cd), lead (Pb) was determined in butterfly pea flower samples by atomic absorption Spectrophotometer (AAS). Method validation was evaluated through of parameters such as linear range, the limit of detection (LOD), the limit of quantitation (LOQ), recovery, repeatability, and intermediate precision. The validation results showed that the LOD of Cd, Pb were 1.20 and 6.20 μg/kg, respectively, while the LOQ of Cd and Pb were 4.01 and 20.5 μg/kg, respectively. The recovery of Cd is 96 - 98% and Pb is 98 - 100%. The relative repeat standard deviation (RSDr) of Cd, Pb is in the range of 1.50 - 2.50% and 1.90 - 2.13%, respectively. Meanwhile, the intermediate precision of Cd, Pb is 2.02% and 1.97%, respectively. The working range of the method is 0.2 - 4 μg/L (Cd) and 3 - 30 μg/L (Pb) with the standard curve equations having the correlation coefficient R2 ≥ 0.995. The quantitative method of Cd, Pb by atomic absorption Spectrophotometer is accurate and highly reliable, used to analyze butterfly pea flower samples collected in Cai Rang district, Can Tho city.  
Determination of chlorate and perchlorate in pangasius samples by liquid chromatography tandem mass spectrometry (LC-MS/MS)
Authors: Huynh Thi Ngoc Lien , Co Hong Son , Nguyen Van Luy ,   National Agro-Forestry-Fisheries Quality Assurance Department-Branch 6, Can Tho, Vietnam,   National Agro-Forestry-Fisheries Quality Assurance Department-Branch 6, Can Tho, Vietnam,   National Agro-Forestry-Fisheries Quality Assurance Department-Branch 6, Can Tho, Vietnam
Published: October 2022

The LC-ESI-MS/MS method has been successfully developed for determination of chlorate and perchlorate in pangasius samples. Residues of chlorate and perchlorate in the sample were extracted with a methanolic solution acidified with 1% formic acid. Then, the extract was cleaned with C18 powder, used a normal phase column to separate chlorate and perchlorate, and quantified on an LC-ESI-MS/MS instrument. The method was validated for good specificity, linear calibration curve in the range of 0.0005 - 0.015 mg/L; the limit of quantification (LOQ) was 0.005 mg/kg; the recovery and relative standard deviation was from 91 to 109% and from 6.4 to 9.5% respectively and all met the requirements of SANTE. The method was applied to the real analysis, a total of 427 pangasius fillet samples collected from seafood processing companies. There were 76 samples were detected chlorate equivalent to 18%. The concentration of chlorate ranged from 0.43 to 253 mg/kg.  
Determination of taxifolin in functional food samples by high - performance liquid chromatography (HPLC - UV Vis)
Authors: Nguyen Thi Que Mai , Do Thi Hoa , Ngo Thi Thu Phuong , Pham Nguyet Cam ,   Quality of Control, Vietnam Institue of Dietary Supplements, Hanoi, Vietnam,   Quality of Control, Vietnam Institue of Dietary Supplements, Hanoi, Vietnam,   Quality of Control, Vietnam Institue of Dietary Supplements, Hanoi, Vietnam,   Quality of Control, Vietnam Institue of Dietary Supplements, Hanoi, Vietnam
Published: October 2022

A method using high performance liquid chromatography with UV - Vis detector was developed for quantification of taxifolin in supplements. In this study, the supplements were homogenized, extracted by ultrasonication with methanol. Taxifolin in test solution was separated on C18 column (250 × 4.6 mm, 5 µm) with mobile phase containing methanol and 0.3 % acetic acid solution (40 : 60) using isocratic elution at a flow rate of 1.0 mL/min, with UV detection at 290 nm. The analytical method was validated for specificity, linearity, precision and accuracy according to AOAC. The detector response for taxifolin was linear over the selected concentration range from 1.04 to 78.23 µg/mL with a correlation coefficient 0.9996. The repeatability (RSD, n = 7) were from 1.1 to 1.4 % respectively. The recovery was between 98.1 and 105.9 %. The method was successfully applied for analysis of taxifolin in 7 supplements at solid, liquid and oil form.
Determination of resistant starch content on food samples by enzyme method
Authors: Doan Thu Thuong , Mac Thi Thanh Hoa , Tran Hung Son , Cao Cong Khanh ,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam,   National Institute for Food Control, Hanoi, Vietnam; Korea Institute of Science and Technology (KIST), Seoul, Korea,   National Institute for Food Control, Hanoi, Vietnam
Published: October 2022

Resistant Starch is a type of fiber of increasing interest due to its beneficial effects on human health. This study has validated the method of determining resistant starch content according to AOAC 2002.02 method. The method has been validated with parameters of calibration curve, repeatability, intermediate reproducibility, and accuracy as required by AOAC. The robustness of the method was evaluated by comparing the content of total resistant starch and digestible starch with the total starch content according to the AOAC 996.11 method. The method has been applied to analyze 36 real samples, the results show that the content of resistant starch varies, ranging from 1 - 42 % depending on the origin, structural characteristics and the way starch is modified.  
Electrochemical detection of Sudan based on Ni/Graphene modified screenprinted carbon electrode
Authors: Luong Thi Thuy Dung , Nguyen Anh Tuan , Nguyan Van Thuc , Nguyen Xuan Hoan , Nguyen Xuan Viet ,   Faculty of Chemistry, VNU University of Sicence, Hanoi, Vietnam,   Institute of Science and Technology (H09), Hanoi, Vietnam,   Faculty of Chemistry, VNU University of Sicence, Hanoi, Vietnam,   Faculty of Chemistry, VNU University of Sicence, Hanoi, Vietnam,   Faculty of Chemistry, VNU University of Sicence, Hanoi, Vietnam
Published: October 2022

In the work reported here, the simple and efficient modification of Ni nanoparticles /reduced graphene (rGO) on the surface of the screen-printed carbon electrode (SPCE) was demonstrated. The obtained composited materials were characterized by physicochemical methods such as SEM and electrochemical techniques. The results show that the Ni nanoparticles are uniformly distributed on the surface of the reduced graphene material with the particle size from 10 - 20 nm. The electrochemical properties show that the Ni/rGO/SPCE material exhibits high electron exchange ability in 0.1 M KOH media. In addition, the Ni/rGO composited material modified SPCE to form a Sudan electrochemical sensor. The sensor has high sensitivity (9.13 µA. µM-1.cm-2), wide dynamic range (300 nM - 35,000 nM) and low limit of detection - LOD (171.8 nM (3*σ). The combination of a miniaturized 3-electrode system (12.5 mm x 4 mm x 0.3 mm) with a highly electrochemical activity of Ni/rGO composited material pave the prospect for the creation of a new type of electrical sensor: compact, high sensitivity in the analysis of Sudan I in particular and in the analysis of banned substances in food in general.  