bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring pain management practices among nurses in a provincial city of Vietnam: A cross-sectional investigation of influential factors
Authors: Nguyen Nga Thi , Nguyen Huyen Thi Hoa , Duong Hoang Huy , Truong Anh Tuan , Tran Duc Quang
Published: August 2024

Background & Aim: There is limited evidence regarding pain management practice and its associated factors among nurses in Vietnam. Therefore, the study aimed 1) To examine the current state of pain management practices among nurses at Hai Duong Provincial General Hospital, Vietnam; and 2) to identify its associated factors.
Methods & Materials: A cross-sectional study design was performed on 200 nurses and 200 medical records needed to be reviewed to match the number of nursing samples. The data collection was conducted from May to June 2022. The modified Cancer Pain Practice Index included 13 evidence-based pain management Indicators applied to measure nurses’ pain management practice by reviewing medical records, and the Knowledge and Attitudes Survey Regarding Pain tool was used to assess the pain management knowledge and attitude of nurses by self-completed questionnaire.
Results: A significant majority, comprising 146 nurses (73%), demonstrated inadequate pain management practices. Several crucial indicators of pain management were suboptimally performed by the majority of nurses. These included failure to document the execution of pain assessments for new patients, inadequate monitoring for side effects of opioid analgesics, and insufficient assessment and care for bowel status when opioids were prescribed. Additionally, participation in prior pain management training courses, along with knowledge and attitude toward pain management, emerged as significant variables associated with pain management practices (p<0.001).
Conclusion: The study highlighted widespread poor pain management practices among nurses. Participation in training courses and good knowledge and attitude correlate with better practices.
Cost Analysis Study of Topical Anti-Acne Drugs Currently Available in Indian Pharmaceutical Market
Authors:   Department of Pharmacology, Assam Medical College and Hospital, Dibrugarh, Assam, India, Gohain Neelomjyoti , Saikia Hiteswar , Chaliha Meghali
Published: August 2024

Acne vulgaris is a chronic inflammatory skin disease that affects approximately 90% individuals between puberty and 30 years of age at some point with peak prevalence in adolescence. According to Global Burden of Disease study conducted in 187 countries in 2010, acne is among top ten most prevalent disease worldwide and skin conditions are top cause of years lived with disability. The aim of the study was to analyze cost variations of different brands of topical medications used in Acne vulgaris in India. This analytical study was conducted in the Department of Pharmacology at Assam Medical College and Hospital over a period of 3 months. ‘‘Current Index of Medical Specialities (CIMS)’’ April - July, 2023 and “Drug Today India April –July 2023’’ drug manuals were used to compare cost of different formulations of topical acne medications. Drugs manufactured by only 1 company were excluded. Cost ratio (Maximum cost/ Minimum cost) and percentage cost variation ([{Max cost – Min cost}/ Min cost] *100) were calculated. For single preparations, the percentage cost variation was maximum for Clindamycin 1% 20 grams gel (1126.66%) with maximum cost ratio followed by Tretinoin 20 gm 0.025% (cream) 721.428. Percentage cost variation was minimum with Adapalene 0.1 % cream 15gm (32.69). Among the combination topical drugs, the percentage cost variation was maximum for Clindamycin 1% + Adapalene 0.1% 15 grams gel (1843.589) and it had maximum cost ratio of 19.43. Percentage cost variation was minimum with combination of Benzoyl Peroxide 2.5% + Clindamycin 1% 20gm gel(41.025).This study highlights price variation among different brands of drugs in CIMS, Drug Today and Pharma Sahi Daam app. Keywords Cost Analysis, Acne vulgaris, Percentage Cost­Variation, Pharma Sahi Daam
Potencial terapêutico dos fármacos pioglitazona, nimodipina e ambroxol na doença de Parkinson
Authors: Ribeiro Leite Celestino Vanessa , Vítor Queiroz Gomes Hugo , José de Souza Silva Laerte , Ferreira do Nascimento Silva Laryssa , De Andrade Tenório Cavalcanti Camilla , Cardoso Campos de Assunção Beatriz , Da Silva Mendonça Polliany , Mota Fonseca da Silva Fábio Antônio , Germano Crispim Joelson , Silveira Duarte Filipe
Published: August 2024

Introdução: A Doença de Parkinson (DP) é uma doença neurodegenerativa, de curso crônico e progressivo, e, até o presente momento, incurável. O tratamento atual limita-se apenas na redução paliativa do déficit motor, visando melhorar a qualidade de vida do paciente. Objetivo: Utilizando a estratégia do reposicionamento de fármacos, o presente estudo teve por objetivo identificar e avaliar novas potenciais indicações terapêuticas para fármacos utilizados na prática clínica, que possam atuar como agentes modificadores da DP. Método: Realizou-se uma busca nas bases de dados PubMed, Scopus e Lilacs, nos últimos 5 anos (2018-2023), utilizando a combinação dos descritores e operadores booleanos, em inglês e português: (“Pioglitazone” OR “Ambroxol” OR “Nimodipine”) AND (“Neuroprotection” OR “Parkinson Disease”). Resultados: A pioglitazona, um antidiabético oral, pode ter efeitos neuroprotetores na DP, reduzindo a inflamação e a morte neuronal. O ambroxol, um agente mucolítico, mostrou-se eficaz na redução do estresse oxidativo e da neuroinflamação da DP. A nimodipina, atualmente utilizado na profilaxia e tratamento das isquemias neurológicas, pode ter efeitos neuroprotetores na DP, atenuando a morte neuronal. Conclusão: O reaproveitamento de medicamentos pode ser uma estratégia terapêutica viável para a DP, e os fármacos supracitados mostram-se promissores para a terapia da condição. Palavras-chave: Doença de Parkinson, neuroproteção, pioglitazona, ambroxol, nimodipina.
SISTEMA NERVOSO E DOENÇAS AUTOIMUNES: UMA REVISÃO
Authors: Crispim Joelson , Cavalcante Muniz Celina , Gabriel Menezes Bezerra Ykaro , Emanuelle Pereira Santos Vanessa , Ribeiro Leite Celestino Vanessa , Ariane Silva Vital de Souza Ariane , Junior Siqueira Gama Elton , Rafaelle Bernardo da Silva Bruna , Camilla de Andrade Tenorio Cavalcanti Camilla , Jesus Barreto de Melo Rêgo Moacyr , Cristiny Pereira Michelly , Galdino da Rocha Pitta Maira , Melgarejo da Rosa Michelle
Published: August 2024

O sistema nervoso autônomo (SNA) atua na liberação de respostas inflamatórias agudas e crônicas, por meio de mecanismos de resposta distintos. Na presente revisão, exploraremos os principais mecanismos de regulação do sistema nervoso, central e periférico, associados aos processos inflamatórios e os seus mecanismos de resposta às doenças autoimunes. O sistema nervoso simpático (SNS) exerce um papel significativo na regulação da mobilização de linfócitos na corrente sanguínea. Esse controle é efetuado por meio da interação direta das catecolaminas com o β2AR, receptor beta-adrenérgico, presente na superfície dos linfócitos, evidenciando a interconexão entre o sistema imunológico e o SNA. As células imunológicas desempenham um papel na síntese e liberação de substâncias tradicionalmente designadas como neurotransmissores e neuromoduladores, incluindo acetilcolina, dopamina e outras catecolaminas, desempenhando funções importantes na regulação imunológica local e em circuitos neuro imunomodulatórios mais complexos. Os avanços recentes na pesquisa sobre a comunicação  neuro-imunológica ressaltam a necessidade de investigações adicionais sobre essas interações para identificar potenciais alvos terapêuticos a patologias auto-imunes que ainda apresentam desfecho clínico insatisfatório.
 
Palavras-chave: citocinas, inflamação, noradrenalina
Effectiveness of ClariFix (Cryoablation) of the Posterior Nasal Nerve on Nasal Symptoms in Patients With Chronic Rhinitis: A Systematic Review and Meta-Analysis
Authors: Choi Bo Yun , Hwang Se Hwan , Kim Do Hyun
Published: August 2024

Background and Objectives: The present study evaluated the efficacy of cryoablation of the posterior nasal nerve in alleviating symptoms associated with chronic rhinitis.Methods: A systematic review of pertinent literature sourced from PubMed, Scopus, Embase, Web of Science, and Cochrane databases was conducted through May 2024. The analysis focused on studies that appraised changes in quality of life and rhinitis-associated symptomatology before and after cryoablation treatment.Results: A total of seven studies (495 patients) were included in the analysis. Significant improvements in rhinitis-related symptoms were observed in patients undergoing cryoablation, irrespective of etiology (allergic or nonallergic rhinitis). Furthermore, cryoablation yielded improvements in disease-specific quality of life, as measured by the Rhinoconjunctivitis Quality of Life Questionnaire. Notably, a clinically significant reduction (≥30% decrease from baseline) in total nasal symptomatology was noted in 71% of cases following cryoablation. Regarding the incidence of adverse effects, nasal dryness, epistaxis, ocular symptoms, and palatal numbness occurred in <5% of patients, while postoperative pain occurred in 10% and headache in 20% of patients who underwent treatment. In subtype analysis, the total nasal symptom score in nonallergic rhinitis showed a significantly increasing pattern over time (p=0.0017).Conclusion: Cryoablation of the posterior nasal nerve appears to yield a decrease in subjective nasal symptom scores and an improvement in disease-specific quality of life. Notably, these effects persisted for up to 12 months post-treatment, with marked improvements observed in both allergic and nonallergic rhinitis subtypes.
Hamartomatous Polyp of the Palatine Tonsil in an Adolescent: A Case Report
Authors: Kwak Soo Un , Kim Jae Hyeong , Shin Jae Min , Kim Tae Hoon
Published: August 2024

A hamartoma is a benign tumor that arises from the disorganized proliferation of tissue and can occur anywhere in the body. Hamartomas are notably found in the lung, skin, heart, brain, and breast, while their occurrence in the head and neck is rare. We describe a case involving a 17-year-old male patient who presented with a mass in a unilateral palatine tonsil, discovered incidentally. The patient was treated with tonsillectomy and, after pathological review, was diagnosed with a hamartomatous polyp of the palatine tonsil. Our case report highlights this rare benign neoplasm and presents a review of the literature.
Qui Sont les Femmes en Union Sans Intention d’Utilisation de la Contraception Moderne au Burundi ? Etude du Profil Socio-Démographique à Partir des Données de 2010 et 2016-2017
Authors: François Régis Sindayihebura Jean , Franklin Bouba Djourdebbe , Didier Nganawara , Désiré Manirakiza , Willy-Marcel Ndayitwayeko , Emmanuel Barankanira , René Manirakiza
Published: August 2024

Dans un contexte qui réclame la maîtrise de la fécondité pour atteindre les objectifs nationaux et mondiaux du développement, la prévalence contraceptive au Burundi reste faible. De surcroît, la proportion des femmes en union sans intention de recourir à la contraception moderne a récemment augmenté. Cette proportion est passée de 53% en 2010 à 66% en 2016-2017. En se basant sur les données des Enquêtes Démographiques et de Santé du Burundi (EDSB) réalisées en 2010 et 2016-2017, cette étude a pour objectif de déterminer le profil socio-démographique des femmes sans intention de contraception moderne. Pour atteindre cet objectif, une Analyse Factorielle des Correspondances Multiples (AFCM) a été utilisée. Les résultats de l’étude montrent que l’âge avancé de la femme et de son conjoint, la parité atteinte élevée et le nombre élevé d’enfants survivants sont les principales caractéristiques de ces femmes. Ces résultats révèlent un problème culturel de fond car ces générations avancées sont sans niveau d’instruction et ne sont ni exposées aux médias ni ouvertes à la modernité. Les interventions futures pour la planification familiale réussie viseraient le changement de vision face à la contraception, tout en encourageant la scolarisation des filles. In a context that calls for fertility control to achieve national and global development goals, contraceptive prevalence in Burundi remains low. Moreover, the proportion of women in the union without the intention to use modern contraception has recently increased. This proportion increased from 53% in 2010 to 66% in 2016-2017. Based on data from the Demographic and Health Surveys of Burundi (DHSB) conducted in 2010 and 2016-2017, this study aims to determine the socio-demographic profile of women without the intention to use the modern contraceptive. To achieve this objective, a Multiple Correspondence Factorial Analysis (MCA) was used. The results of the study show that the advanced age of the woman and her partner, the high number of children ever born and the high number of surviving children are the main characteristics of these women. These results reveal a fundamental cultural problem as these advanced generations are uneducated and are neither exposed to the media nor open to modernity. Future interventions for successful family planning would aim at changing the vision towards contraception while encouraging girls' schooling.
Assessment of the quality of life of pregnant women with pubic and lower back pain when using kinesiotaping
Authors: Vorobyov Alexander A. , Selikhova Marina S. , Yakovenko Marina S.
Published: August 2024

Physiologically determined changes in the musculoskeletal system during pregnancy lead to the development of pain syndrome in the pubic area and lower back, which in turn lead to a decrease in the quality of life. Materials and methods: Evaluation of the effectiveness of kinesiotaping in symphysiopathy and dorsopathy during pregnancy with respect to the level of quality of life using the validated SF-36 questionnaire "Quality of Life Assessment", the Oswester questionnaire of disability in lower back pain and the Roland – Morris questionnaire "Lower Back pain and disability". Results: In both groups (control and observation), there is a decrease in the level of individual components of quality of life, while the "Physical component" has statistically significant differences between the groups, excluding "Role functioning due to physical condition", which shows a higher level of quality of life in group 2. When assessing the Psychological component, statistical differences between the groups were not revealed it was. According to the results of statistical analysis conducted on the basis of the Oswestry questionnaire, the level of quality of life in group 2 was also significantly higher than in group 1. According to the Roland-Morris questionnaire, it was revealed that despite the higher level of quality of life in group 2, confirmed in our study, disorders in both groups they are still defined as expressed. The most common complaints that reduce the quality of life in pregnant women with pain in the womb and lower back were also identified. Conclusions: Since the quality of life is an integral indicator of most aspects of life, this indicator can be considered the most successful for evaluating the effectiveness of treatment.
The effect of the size of the bone defect of the glenoid on graft resorption after Latarge surgery
Authors: Tregubov Andrey S. , Cherezov Leonid L. , Zhulikov Alexander L. , Malanin Dmitry A.
Published: August 2024

Graft resorption can be an obstacle to achieving good functional results during Latarge surgery. One of the factors influencing the possible development of osteolysis is the size of the defect of the articular process of the scapula. This article presents an analysis of the relationship between the preoperative magnitude of the glenoid defect and subsequent osseointegration of the graft after Latarge surgery.
Anemia of chronic diseases
Authors: Pavlova Vera Yu. , Kazakovtseva Elizaveta V.
Published: August 2024

Anemia of chronic diseases (ACD) is a pathological process that develops in patients with systemic inflammation in a wide range of diseases of both infectious and non-infectious origin. ACD is the second most common disease in the world after iron deficiency anemia (IDA) and is a factor that aggravates the course of the underlying disease and increases mortality. Pathophysiologically, ACD is a complex multifactorial process and includes 3 main development mechanisms: an increase in the production of hepcidin, a decrease in the formation of erythropoietin and inhibition of normal erythropoiesis in the bone marrow. These processes are triggered by pro-inflammatory cytokines. Special attention in the article is paid to the universal humoral regulator of iron metabolism – hepcidin. For a doctor of any specialty it is important to identify ACD, conduct a differential diagnosis that allows one to distinguish ACD from other types of anemia (including iron deficiency), establish a possible combination of IDA and ACD, since different types of anemia require their own therapeutic approaches. The patient’s prognosis will depend on the correct treatment. In order to verify ACD a thorough search for the underlying disease is carried out, СBC indicators and iron metabolism indicators are assessed. The basis of the therapeutic approach to the treatment of ACD is the treatment of the underlying disease. Therapy for this type of anemia includes the use of iron preparations, erythropoietin and replacement therapy with blood components.
The role of morphofunctional asymmetries of the female body in the autonomic regulation of heart rate during menopause
Authors: Botasheva Tatyana L. , Fabrikant Ilya M. , Gorbaneva Elena P. , Zheleznyakova Elena V. , Zavodnov Oleg P. , Zmienko Vera A. , Gurbanova Lala R. , Khloponina Maria D.
Published: August 2024

The aim of the work was to study the features of autonomic regulation of heart rhythm (HR) in women in the peri- and postmenopausal periods, depending on morphofunctional asymmetries of the female body. A total of 417 women aged 35–60 were examined. According to the lateral behavioral profile of asymmetries of the female body (Annette’s test), the nature of vegetative regulation at rest and orthostasis was determined according to the data of cardiac intervalography using the Varicard 2.51 complex and the Eskim-6 program. As a result, it was found that in the reproductive period in women with the right lateral phenotype, the autonomous circuit of HR variability regulation prevailed, and in ambidextrous women, the central one dominated. Ambidextrous and right-handers were characterized by egalitarian modulation, while left-handers were characterized by a respiratory typology of autonomic regulation of HR. In perimenopause, a moderate tension of regulatory mechanisms was formed in the lateral subgroups, and a high tension was formed in the postmenopausal subgroups. In ambidextrous and left-handers, discoordination of HR regulation prevailed. Thus, women with the polarity of the lateral phenotype in the late reproductive period were distinguished by the stability and economy of the mechanisms of autonomic regulation of HR. Ambidextrous had the most energy-consuming mechanisms in the postmenopausal period, which is a risk of cardiovascular disease pathology.
In Silico Toxicological Analysis of Active Compounds Present in Selected Pesticides Sold in South-West Nigeria
Authors: Daniel Uwaremhevho Momodu  , Toluwase Hezekiah Fatoki  , Alebiosu Oluwaseyi Samuel , Ojo Deborah Ebunoluwa , Akinlolu Olapade Samuel , Oyebanji Adedayo Olamide
Published: August 2024

Introduction: The study investigated the molecular effects of human exposure to commonly used pesticides in Nigeria. Methods: Utilizing computational methods like clustering analysis, toxicokinetic predictions, molecular docking, and molecular dynamic (MD) simulation, various health impacts were identified. Results and Discussion: The results revealed significant gastrointestinal absorption, P-glycoprotein bypass, blood-brain barrier penetration, and cytochrome P450 inhibition for certain pesticide agents. Notably, oxathiapiprolin showed hepatotoxicity, propanil exhibited drug-induced liver injury (DILI), and 2,4-dichloro-phenoxyacetic acid demonstrated carcinogenicity. Respiratory toxicity was predicted for most pesticides, except propanil and N-(2,6-diethylphenyl) acetamide. Molecular targets were identified, such as bifenthrin targeting programmed cell death 1 ligand 1 and Atrazine targeting potassium voltage-gated channel subfamily H member 3. Binding affinities were computed, with oxathiapiprolin showing -6.526 kcal/mol with short transient receptor potential channel 7. Molecular dynamic simulations indicated significant binding energy changes over time. Atrazine's binding with potassium voltage-gated channel subfamily H member 3 exhibited a total binding energy ΔGbind of -39.410 kcal/mol and -49.135 kcal/mol at 0 ns and 100 ns, respectively. Oxathiapiprolin's binding with short transient receptor potential channel 7 showed ΔGbind of -53.481 kcal/mol and -44.122 kcal/mol at 0 ns and 100 ns. Conclusion: This study suggests potential hepatotoxicity and carcinogenicity of certain pesticides, emphasizing the need for environmental monitoring and stringent regulations to safeguard public health.
Lead Contamination in Pangasius Djambal in the Dam of Kalitidu District, Bojonegoro District: An Environmental Health Risk Study
Authors: Husniyah Ami , Nurika Globila , Ellyke Ellyke
Published: August 2024

Introduction: One of the areas passed by the Bengawan Solo River is Bojonegoro. Many Bojonegoro people find fish at the point of Bendung Gerak, Ngringinrejo Village. One of the fish that is often caught is Pangasius djambal. At this location, the dominant waste contamination comes from agricultural and domestic waste. Lead can contaminate water and enter through the food chain in fish which are later eaten by humans. The purpose of this study was to analyze the environmental health risk of lead (Pb) content in Pangasius djambal in Bendung Gerak Ngringinrejo Village, Kalitidu District, Bojonegoro Regency. Methods: This research used field environmental health risk analysis method. The total sampling of the community was 50 respondents and was taken using accidental sampling. Community sample criteria are those who consume Pangasius djambal within 1 year. Environmental samples are Pangasius djambal taken at 3 points and analyzed using the Atomic Absorption Spectrophotometry (AAS) method. Results and Discussion: The results showed lead intakes at points A, B, and C were 0.0018 mg/kg/day, 0.0639 mg/kg/day, and 0.0012 mg/kg.day, respectively. The results show the RQ value of point B RQ>1 (unsafe), while points A and C are RQ≤1 (safe). It can be caused by several factors such as body weight, intake rate, consumption frequency, exposure duration, and lead concentration. Conclusion: Based on these results, it is necessary to do risk management at point B.
Potential Impacts of Lead on Health: A Review of Environmental Exposure, Population at Risk, and Toxic Effects
Authors: Simatupang Meithyra Melviana , Veronika Erna , Irfandi Ahmad , Azteria Veza
Published: August 2024

Introduction: Lead, a heavy metal, has been proven to influence the ecosystem negatively. The use of lead in processing or as raw materials increases Pb exposure to humans from various sources, including waste or consumed products. This study aims to determine the most recent information regarding lead contamination sourced from the environment, at-risk populations, and the health impacts of this heavy metal contamination. Results and Discussion: This systematic review used a database sourced from Google Scholar. The keywords searched were "lead exposure, environment, or health" in articles published in 2020-2023. After article screening and exclusion, 26 research articles were eventually reviewed. Lead was detected in water, air, and soil, generally in various foods or products consumed by humans. Environmental factors were the most frequent source of contamination. The population at risk of lead exposure were children. Several studies have found that various health impacts were significantly associated with lead exposure from different environmental sources and lead concentrations in biomarkers. Conclusion: Pb contamination was increasingly widespread in the environment through various sources. Exposure to lead may cause diverse health problems.
IDENTIFICATION OF MICROFILARIAE USING CONVENTIONAL POLYMERASE CHAIN REACTION AND QPCR-HRM
Authors: Ihsan Bagus Muhammad , Lakshmi Puspita Widyana , Triana Linda , Wahdaniah  , Khayan  , Dani Sucipto Cecep
Published: August 2024

Background: The presence of filarial worms in the lymph nodes can result in acute symptoms, such as inflammation of the lymph nodes and ducts, particularly in the groin region. As part of the life cycle of filariasis, symptomatic or asymptomatic patients with microfilariae in their blood can transmit the disease via mosquito bites. The inspection of microfilariae that is currently being developed uses Polymerase Chain Reaction (PCR) to carry out a unique DNA search technique. Purpose: Identify the type of microfilaria present in filariasis patients using Quantitative PCR High- Resolution Melting (qPCR-HRM) and conventional PCR techniques. Method: This study involved the examination of 19 samples using the qPCR-HRM method. Subsequently, the results that were considered positive for microfilaria underwent further testing using conventional PCR. Result: The results of the examination using these two methods revealed the presence of Brugia malayi and Wuchereria bancrofti microfilariae with peak melting temperatures ranging from 78.2 – 78.7 °C and 80.8 – 81.2 °C, and fragment sizes of 199 bp and 227 bp, respectively. Conclusion: Based on the results of the identification from these two methods, it is evident that microfilariae of Brugia malayi and Wuchereria bancrofti can be detected using both conventional and qPCR-HRM methods.
Solid-state NMR of active sites in TiO2 photocatalysis: a critical review
Authors: Feng Ningdong , Xu Jun , Deng Feng
Published: August 2024

Titanium dioxide (TiO2) is one of the optimal semiconductor metal oxide photocatalysts with a wide range of application fields, such as heterogeneous catalysis, energy science, and environmental science. Solid-state nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for characterizing both structure and dynamics at an atomic-molecular level in heterogeneous catalysts. In this review, we first provide a brief discussion on the progress in investigating the structures of titanium and oxygen in bulk and on the surface of TiO2 by using various solid-state NMR techniques. Advances in the understanding of electronic structure and properties of TiO2 with distinct surface features, including various crystal facets and heteroatomic adsorption by chemical probe-assisted NMR techniques, are secondly presented. The solid-state NMR characterization of heteroatom active sites (such as 13C, 15N, 11B, 27Al) and their function in TiO2 photocatalysts is described in detail. Finally, a critical discourse assesses the current limitations and prospects of solid-state NMR in its application to the optimization and design of advanced TiO2 photocatalysts.
Analisis Usability Testing Menggunakan Metode Cognitive Walkthrough Pada Website PKL ITTP
Authors: Yunita Salsabila Firda , Yuniati Trihastuti
Published: August 2024

Salah satu perkembangan teknologi internet yang paling umum digunakan saat ini adalah website. Website berperan sebagai media untuk menyebarkan informasi secara luas dan menyeluruh, memastikan bahwa informasi dapat sampai ke banyak orang dengan mudah. Contohnya pada Institut Teknologi Telkom Purwokerto untuk menyampaikan informasi dan mengolah data mahasiswa yang sedang melaksanakan PKL. Website yang baik harus dapat diakses secara mudah dan cepat karena mengutamakan kemudahan pengguna sehingga tidak menyebabkan kesulitan. Oleh karena itu kemudahan pengguna menjadi prioritas utama dalam pengembangan sebuah website. Tujuan dari penelitian ini adalah melakukan analisis usability testing pada website PKL Informatika ITTP dan memberikan rekomendasi perbaikan dari kendala yang dialami oleh user. Penelitian akan menggunakan metode cognitive walkthrough dan aspek usability yang diuji adalah learnability, effectiviness, dan efficiency. Berdasarkan analisis yang dilakukan penelitian ini menghasilkan presentase learnability sebesar 100% karena seluruh skenario tugas dapat diselesaikan oleh seluruh responden, effectiviness yang baik karena tidak ada kesalahan saat pengerjaan skenario tugas dan efficiency  dengan rata-rata waktu yang dihabiskan 16,6 detik serta terdapat 5 rekomendasi perbaikan, 3 diantaranya merupakan perbaikan sistem dan 2 rekomendasi lagi adalah perbaikan user interface.
The Alliance in the Storm: Geopolitical Representation of the United States in the Turkish Parliament during Détente
Authors: Atmaca Ayşe Ömür
Published: August 2024

This article analyzes how the geopolitical representation of the United States in Turkish political discourse changed during the 1960s and 1970s in the context of deep crises between the two countries, such as the Cyprus question, the opium issue, and the US arms embargo on Türkiye. Within the framework of critical geopolitical theory, it uses the concept of “geopolitical representation.” It examines the changes in the geopolitical representation of the United States in Turkish political life through practical geopolitics. To this end, it evaluates the debates, speeches, and correspondence made by the representatives of the ruling and opposition parties and members of the government in the Turkish Grand National Assembly between 1964 and 1979, within the context of the crises in Turkish-American relations, particularly within the foreign policy framework. It is argued that while the alliance between Türkiye and the United States and Türkiye’s membership in NATO were seen as important symbols of Türkiye’s sovereignty and enjoyed unwavering support in the 1950s, tensions with the US, Türkiye’s “strategic partner,” in the 1960s and 1970s led to notable shifts in the Turkish parliament’s narrative. As a pioneer of anti-NATO and anti-US rhetoric, the Workers’ Party of Türkiye (TİP) played a prominent role in shaping parliamentary discussions.
An Experimental Study on the Caprock Integrity of Reservoirs to Assess the Repurposing Depleted Bakken Formation Oil and Gas Fields for Underground Hydrogen Storage
Authors: Aluah Rockson , Fadairo Adesina , Opeyemi Oni , Ni Ruichong , Foerster Ian
Published: August 2024

The escalating greenhouse gas emissions have compelled global economies to implement climate change mitigation strategies. Geological hydrogen storage in depleted oil and gas reservoirs emerges as a groundbreaking solution, offering a dual benefit of repurposing existing geological structures while advancing sustainable energy storage, potentially facilitating the transition to a low-carbon economy. However, the potential for hydrogen leakage over extended storage periods is a significant concern. To assess the risk of leakage, it is essential to understand the interactions between hydrogen, brine, and the reservoir caprock integrity. In this study, we collected core samples from three depleted oil and gas reservoirs in the Bakken Formation (W17351, W21884, and W24881), from three distinct fields: Antelope, Alger, and Ranch Coulee. The Upper Bakken formation serves as a seal for potential underground hydrogen storage in the Middle Bakken reservoir. The core samples were subjected to hydrogen and brine exposure under high-pressure, high-temperature (HPHT) conditions in an autoclave reactor for 1 and 5 days to simulate reservoir conditions and assess the impact of hydrogen-brine-caprock interactions on the reservoir's integrity. We analyzed the samples' porosity, permeability, and mechanical properties before and after long-term exposure to hydrogen-brine using Nuclear Magnetic Resonance (NMR), permeability measurements, and ultrasonic measurements, X-ray diffraction (XRD) and scanning electron microscopy (SEM) to assess changes in their properties. The results showed a consistent increase in permeability across all samples, with the magnitude of increase varying based on exposure duration. NMR measurements indicated a substantial, time-dependent increase in porosity for all samples. Mechanical properties, such as Young's modulus and Poisson's ratio, decreased after exposure to hydrogen-brine, suggesting increased susceptibility to deformation and reduced ability to withstand stresses. SEM analysis revealed the development of fracture pores, interparticle pores, and dissolution-induced pores, as well as changes in elemental composition. XRD analysis showed changes in the relative abundances of minerals, with a decrease in clay and quartz content and an increase in K-feldspar content. These findings have significant implications for the integrity and sealing capacity of the Upper Bakken formation when considering its suitability for underground hydrogen storage. The observed changes in permeability, porosity, mechanical properties, microstructure, and mineralogy raise concerns about the potential for hydrogen leakage and the long-term stability of the reservoir seal.
Automation of Greenhouse Gas Emission Estimates Associated with Natural Gas Production in the Appalachian Basin
Authors: Calad C. , Buckinham T. , Mulligan E. , Annab M. , Sarma P. , Betancourt D. , Uribe C , Solano H , Rafiee J.
Published: August 2024

This study seeks to improve the quantification of greenhouse gas (GHG) emissions from unconventional natural gas production in the Appalachian Basin, covering Carbon Dioxide (CO2), Methane (CH4), and Nitrous Oxide (N2O). The goal is to automate the calculation process for compliance with the US Environmental Protection Agency (EPA), corporate sustainability reporting, and internal monitoring for emissions reduction targets. Traditionally, GHG emissions are manually computed once a year and are often calculated by third-party consultants, reducing transparency in calculation approaches. The development of an on-demand GHG emissions inventory enables real-time identification of emission-intensive processes, guiding strategic decisions for emissions mitigation and methane intensity reductions.

In this project, we employed Python and SQL scripts to map activity data related to process and fugitive emissions, including pneumatic devices, drilling and completions combustion, equipment leaks, liquids unloading, dehydrators, and flaring, into US EPA Subpart W formulas. The result is an annualized carbon footprint calculated at the well pad level, providing comprehensive insights into component gasses (CO2, CH4, and N2O), production-based carbon and methane intensities, and emissions contributions by emission source. Automation improved the efficiency and accuracy of the emissions calculation workflow, generating an updated carbon footprint in a runtime under 5 minutes. Additionally, the inclusion of emissions-generating events overlooked due to human error substantially improved the quality of the emissions footprint. Lastly, the employment of data analytics on all calculation inputs and outputs aided in identifying outliers that required modification.

The GHG calculation tool enhances accuracy, transparency, and consistency while minimizing the time invested in GHG estimations, allowing teams to redirect their efforts toward value-added activities. Next steps in the project include detailed emissions forecasting, which facilitates determining the most cost-effective emissions reduction strategy. The mapping of activity data into GHG estimation models was completed within six weeks, with additional time spent in result validation against previous manual calculations. After an initial configuration, data mappings do not require ongoing updates, establishing a fully automated GHG calculation process. This advancement enables efficiency and reliability in monitoring and reporting GHG emissions. Additionally, the development of a granular carbon footprint on an emission source basis enables detailed, source-level emissions forecasting to support future decisions around emission reduction projects.
Transfer of Oilfield Production Chemical Technology to the Renewable Energy Sector
Authors: Jenkins Alyn , McRae Alex , Nelson Alex , Gabbasov Dinar , Pineiro Rolando Perez
Published: August 2024

The transition from fossil fuels to renewable energy is accelerating, which has necessitated the oil and gas industry to investigate which technologies traditionally used in the oilfield can be used in the renewable energy sector. In oil and gas production, chemicals are used to preserve the integrity of production tubing, pipelines, and vessels; prevent inorganic scale deposition; and maintain the flow assurance of the hydrocarbons so that they can be transported from the reservoir to the refinery. Examples of chemicals used for these purposes include corrosion inhibitors, scale inhibitors, hydrogen sulfide (H2S) scavengers, kinetic hydrate inhibitors, demulsifiers, and paraffin inhibitors. Because certain renewable energy industries face challenges similar to those experienced by the oil and gas industry, there is an opportunity for the renewable energy sector to adopt the proven chemical solutions used in oil and gas production. For example, in geothermal energy production, scale deposition, corrosion, and H2S contamination are common problems. Similarly, corrosion poses a significant risk in carbon capture and storage (CCS) applications and for hydrogen transport, and there is the potential for gas hydrates to form in CCS pipelines. All these issues are routinely encountered in the oil and gas industry and can be mitigated through the application of production chemicals. This paper examines how certain oilfield chemicals perform under conditions experienced in the renewable energy industry and investigates how they can be used in this sector.
Semi-Hybrid Models for Determining Gas Solubility in Brines with Salt Mixtures: Application to CCS and Gas Processing
Authors: Ratnakar R. R. , Chaubey V. , Gupta S. , Rui Z. , Dindoruk B.
Published: August 2024

Gas solubility in brine plays crucial role in designing various industrial applications such as oil recovery, CCS, corrosion, and gas processing. However, most studies include only standard salts and may not capture the full spectrum of formation brines. The objective of this work is to develop a semi-hybrid framework that can determine the gas solubility in brine solution at extended pressure/temperature ranges, which is applicable to any gas and salt mixture of choice.

The work includes the coupling of semi-empirical model and machine learning (ML) approach. In particular, it is an extension to Setschenow's correlation where coefficients are evaluated using ML tool based on decision tree (DT). The features in the ML models include the ionic properties of cations and anions, and thermodynamic properties of gases. This work captures combinations of various salts such as chlorides, carbonates/bicarbonates, and sulphates (as they are seen in real formation brines and water utilities applications), and various standard gases (including hydrocarbon, non-hydrocarbon/polar and acidic gases).

A semi-hybrid (physics augmented) framework is developed to estimate gas solubility in brines for a generic gas-brine systems. It is applicable for a wide range of pressures, temperatures, and brine compositions. The prediction from semi-hybrid models were validated against the available experimental data. The main results are as follows:

The Setschenow's coefficients for any cations, anions and gases can be generated within 1 – 3% accuracies. The semi-hybrid models predict the experimental trends of gas solubility in brine solution accurately, within the relative error of 1 – 6% for complex gas-brine systems. Most importantly, the framework is general, fast, convenient and can easily be extended for a novel species including greenhouse or hydrocarbon gases, as well as for variety of salts. Additionally, it can fill the gaps in experimental data for the gas-brine systems, and can extrapolate to elevated pressure and temperature conditions. In this work, the applicability is demonstrated for many salts that are seen in formation brine, and many gases that are used in gas injection/storage and gas processing applications.

The most ML, correlation and EOS-based studies in the literature on estimating gas solubility in brine are restrictive and valid only for specific gases such as CO2 as well as few salts (NaCl/KCl/CaCl2). Here, we develop a semi-hybrid framework that can estimate the solubility of any gas in a given brine composition that could consists of wide range of salts and salt mixtures, which is the main novelty of the work.
The Effects of Co-Capture Impurities on the Phase Behaviour of CCUS Fluid Systems: Experimental Measurements and Thermodynamic Modelling of Vapour-Liquid Equilibria in CO2-Rich System
Authors: Okoro Franklin , Chapoy Antonin , Ahmadi Pezhman , Burgass Rod
Published: August 2024

This study carried out bubble point experimental measurements for CO2-rich binary (CO2-CH4) system using the constant composition expansion method at low temperatures (228.15 – 273.15 K). For all the data points, the measurements' uncertainties were 0.14 K and 0.03 MPa, and a maximum composition uncertainty of 0.03%. The experimental data were used to validate the predictive accuracies of two thermodynamic models - Multi-Fluid Helmholtz Energy Approximation (MFHEA) and Peng-Robinson (PR) equations of state (EoSs). The results revealed that the presence of the impurities increased the bubble point pressures of the mixture, and MFHEA gave a better prediction of the binary system. The literature experimental (bubble and dew points) data also fit both model lines with less than 5% deviations for all the data points. The study also showed that, the lower the temperature, the more significant the effects of the co-capture impurities on the bubble points of CO2. The higher the volume fractions of the impurities, the higher their effects on the bubble points of CO2. Therefore, not considering the presence of the impurities or assuming a pure CO2 in the CCUS process would clearly lead to flow assurance issues like two phase flow when single phase is expected.
Comparative Analysis of Best-In-Class Regulatory Frameworks Implemented in the Petroleum Industry vis-à-vis the Petroleum Industry Act, 2021
Authors: Nwankwo O. K. , Atebe O. J.
Published: August 2024

The passage of the Petroleum Industry Act 2021 (PIA) transformed the Nigerian petroleum regulatory landscape from being oversighted by a single regulator; a task that was largely regulated by the defunct Department of Petroleum Resources (DPR) to a dual regulatory landscape based on value chain administration. Upstream operations are exclusively regulated by the Nigerian Upstream Petroleum Regulatory Commission (NUPRC) while mid and downstream operations are exclusively regulated by the Nigerian Midstream and Downstream Petroleum Regulatory Authority (NMDPRA). This paper examines the economic benefits of the regulatory philosophy enshrined in the PIA and comparatively examines this philosophy vis-à-vis other possible regulatory philosophies to evaluate the most viable regulatory structure for the Nigeria Petroleum Industry. It was established that irrespective of the choice of regulatory framework, the clear separation of streams on the petroleum value chain that was established by custody transfer between them, which was presented by the PIA as its regulatory structure, is the philosophy with economic advantages that should be sacrosanct for any regulatory framework of choice. Moreover, mitigation strategies to reduce regulatory overlaps/conflicts in the implementation of the PIA were proposed given the concerns raised by stakeholders on ease of doing business. Finally, this paper recommends that the development and choice of regulatory frameworks should hinge squarely on critical factors such as the economic benefits to the country, expected long term objectives, clear and unbiased delineation of responsibilities, change management implementation, policy consistency and efficient data management.
Evaluation of Research Progress and Trends on Cement Retarders Application in Oilwells: A Bibliometric Analysis of Literature and Stakeholders
Authors: Nwaichi P. I. , Ridzuan N. , Nwaichi E. O. , Gbonhinbor J. R. , Agi A.
Published: August 2024

Retarders are used to prevent hydration of oilwell cement by prolonging thickening time and setting time, giving enough time for cement slurry application under deep and high-temperature conditions. However, the history and potential research direction of oilwell cement retarder has not been fully investigated. Thus, this study aims to fill these gaps in knowledge by identifying the main themes, influential authors, reputable journals, countries, and emerging keywords in this research area. The VOSviewer software was used to analyze journal articles published between 2000 to 2022 from the Scopus database to achieve the history, emerging keywords and potential research direction of oilwell cement retarder. The results show that 1,217 research articles on oilwell cement retarders have been published. Additionally, emerging keywords such as alkaline-activated slags, inorganic polymers, geopolymers, curing, slag grouting, and magnesia have gained recent attention. Authors from China, the United Kingdom, the United States, Spain, and South Korea contributed over 50% of the cited publications within the selected years. The findings provide valuable insights into previous studies on cement retarder applications, allowing for a deeper understanding of the research area, identifying the research gaps, highlighting potential research directions and collaborators.
Effect of Oil Polarity on Surfactant Foam Properties at Bulk and Macroscopic Scale
Authors: Balakirisnan A. , Jaafar M. Z. , Sidek M. A. , Yakasai F. , Nwaichi P I. , Ridzuan N. , Mahat S. Q. A. , Abbas A. H. , Ngouangna E. , Gbadamosi A. , Oseh J. O. , Gbonhinbor J. R. , Agi A.
Published: August 2024

Recent studies on oil-foam interaction using different types of oil were limited to the aspect of alkane chain length, density and viscosity of crude oil. However, oil polarity toward foam stability to predict the significant variable of the foam half-life and its evaluation in macroscopic oil displacement is still elusive in literature. In this study, the effect of oil polarity on foam properties at bulk and macroscopic scales was investigated. The effect of electrolytes on surfactant foam stability was studied. Subsequently, the foam stability in the presence of polar and non-polar oil was determined. Thereafter, the macroscopic oil displacement efficiency of surfactant foam was evaluated. Finally, a multivariate linear regression analysis was used to predict the significant variable of the foam half-life. The results indicate that cocamidopropyl betaine (CAPB) foam had better stability under the influence of oil polarity, with a half-life decrease of 8% in hexane oil compared to 86% by sodium dodecyl sulfate (SDS). Moreover, SDS foam flooding recovered 10% additional oil compared to 5% CAPB foam. However, oil recovery in the presence of pyridine decreased oil recovery of SDS and CAPB foam flooding to 6% and 3%, respectively. Likewise, mobility reduction factor (MRF) of SDS foam decreased by 74% compared to 39% by CAPB foam. However, both MRF of SDS and CAPB foam drop drastically by 81% and 90%, respectively in the presence of pyridine compared to hexadecane. Finally, the multivariate regression analysis indicates that surfactant is the most significant variable with a P value below 0.0001. The R2 proportion of variation in the response attributed to this model was 0.81, with a root mean square estimation of 5.2386.