bluuebunny/crossref_metadata_2025 huggingface dataset:
Expression of voice relation in the languages of different structure: is there a category of voice in Hungarian?
Authors: Guskova Antonina P.
Published: April 2022

Introduction. This article is a development of an earlier study on the grammatical categories of the verb in Hungarian in comparison with Russian. The subject of study in this work is the grammatical category of voice, one of the most common verbal categories, typical for Russian verbs and absent in the Hungarian language, as well as the ways of its transmission when translated into Hungarian. The purpose of this work is to analyze the grammatical forms of the Hungarian and Russian verbs expressing voice relations and to establish the corresponding equivalents of the category of voice in Russian in the Hungarian language.
Materials and Methods. The research material is verbal vocabulary selected from lexicographic works (dictionaries of the Hungarian and Russian languages), linguistic and journalistic sources, grammars of the Hungarian language. The article considers both the written form of the modern Hungarian language and examples from live colloquial speech. The methodological framework of this study is based on researches on general linguistics, the theory of morphology, contributing to the formulation of the problem, determining the degree of its development in the research literature, as well as familiarizing with the conceptual approaches to the voice as an ambiguously interpreted grammatical category of the verb. The methods used in the study are comparative-typological, synchronous-descriptive and functional-semantic methods.
Results and Discussion. In the course of study it revealed how inflectional and derivational means helping to express the grammatical semantics of the category of voice in Russian can adequately convey the categorical meaning in the Hungarian language, in which the category of voice is absent. The comparative study of two languages helps to identify the features inherent in each of them, which generally contributes to solving the problems associated with the practice of their teaching. The results of the work based on the data of the ongoing research may be useful in the analysis of other grammatical categories on the material of various languages.
Conclusion. Despite the fact that verbs in the Hungarian language do not have a passive voice, the means and forms of its expression are represented in it by a developed and diverse system. The study allows making a step forward in understanding the typological specifics of the voice category and make a certain contribution to the general theory of this phenomenon, since it was the first study of the verb forms of two heterogeneous, genetically unrelated languages based on a comparative analysis in grammatical, semantic and functional aspects.
Divergent we fall: The challenges for welfare state - Social integration and unemployment policies in the Visegrad Countries
Authors: Hungler Sára
Published: April 2022

This article examines the unemployment policy of Central-East-European countries applying mixed methods. First, fuzzy set analysis is used to determine the efficiency of unemployment measures for reducing the poverty gap. Three causal conditions are measured: the net replacement rate of unemployment benefits, labour law regulations related to job security, and public spending on labour-market programs. This analysis reveals two possible pathways: governments may either provide a high level of job security, or spend on active and passive labour-market measures. Second, the fuzzy set analysis was completed with a comparative legal analysis covering the Visegrad countries that examined the policy choices the Visegrad countries made after the economic crisis. The paper argues that due to the different approaches to the welfare state, any potential EU initiatives for regulating unemployment benefits under the European Pillar of Social Rights might put divergent adaptation pressure on the V4 states. The differences are significant, as they would not only challenge effective social integration but also hamper the envisioned political cooperation of the V4 countries in this policy area. Building on previous literature, this paper is written to contribute to research on the European Social Model and social integration within the European Union.
مفهوم التعليم في سورة لقمان الاية ١٢-١٩ عند تيسير كريم الرحمن في تفسير كلام المنان لعبد الرحمن بن ناصر السعدي
Authors: Alfarouq Mohammad Hendri , Meinaldi Lutphi
Published: April 2022

تهدف هذه الدراسة إلى وصف: مفهوم التربويين في سورة لقمان: ١٢-١٩ ومدى انعكاساته على التربية الإسلامية. يستخدم الباحثون المناهج النوعية والأساليب الوصفية لأنها تستند إلى تحليل الوثائق (الكتب والأوراق العلمية والملاحظات وغيرها من المعارف). تظهر نتائج الدراسة أن ١) يجب أن يكون لدى التربويين معرفة مؤهلة للتدريس، وأفعال جديرة بالثناء على الصعيدين الداخلي والداخلي، ويسعون جاهدين للتنسيق بين المعرفة والإحسان، وأن يتمتعوا بطبيعة عطوفة وصادقة. ٢) يجب على الطلاب التحلي بالصبر في تلقي الدروس. ٣) تهدف التربية الإسلامية إلى التأكيد على العبودية الحسنة لله في الإيمان والعبادة، وامتلاك الشخصية الطيبة والقدرة على التفاعل بشكل جيد مع إخواننا من البشر. ٤) مواد الإكراه هي: العقيدة، والعبادة، والأخلاق، والدعوة. ٥) طريقة التعليم الموجودة هي ترغيب وترهيب ومثالية. ٦) من خلال تنفيذ المفهوم التربوي لـسورة لقمان: الآيات ١٢-١٩ الذي يؤكد على أهمية التوحيد، من أجل تجنب تفكير الغربيين. Penelitian ini bertujuan untuk mendeskripsikan konsep pendidik dalam Surah Luqman: 12-19 serta bagaimana implikasinya terhadap pendidikan Islam. Peneliti menggunakan pendekatan kualitatif dan metode deskriptif  karena didasarkan pada analisis dokumen (buku, karya tulis ilmiah, catatan dan literasi lainnya). Hasil penelitian menunjukkan bahwa 1) Pendidik harus memiliki ilmu yang mumpuni untuk diajarkan, perbuatan yang terpuji baik dzohir maupun batin, berupaya menyelaraskan ilmu dan amal, memiliki sifat penyayang dan ikhlas. 2) Peserta didik dituntut bersabar dalam menerima pelajaran. 3) Tujuan pendidikan Islam menekankan baiknya penghambaan kepada Allah baik aqidah maupun ibadah, memiliki kepribadian yang baik dan dapat berinteraksi dengan baik sesama manusia. 4) Mata pelajaran wajib adalah aqidah, ibadah, akhlak dan dakwah. 5) Metode pendidikan yang ditemukan targhib wa tarhib dan keteladanan. 6) Dengan menjalankan konsep pendidikan Surah Luqman: 12-19 yang menekankan terhadap pentingnya tauhid maka akan terhindar dari paham barat.
Improving students' Spiritual Intelligence Through Compulsory Dormitory Program
Authors: Surawan Surawan , Sobari Rahmat Tawakkal
Published: April 2022

Spiritual Intelligence is one of the three types of intelligence. It has a fundamental role, especially in Islamic education. As one of the Islamic higher education institutions,  IAIN Palangka Raya has a unit named Ma'had Al-Jami'ah IAIN Palangka Raya. This technical implementation unit aims to be a support system in building and forming religious and insightful students. This study aims to determine what programs Ma'had Al-jami'ah IAIN Palangka Raya organize to train students’ spiritual intelligence. The method used is an observation method with the target of Islamic Religion Education 2021 generation Rolling 1st students. However, in the direction of the compulsory dormitory program aims to train the Spiritual Intelligence of all parties involved in Ma'had Al-Jami'ah IAIN Palangka Raya, both advisors, and students. The results show that the compulsory dormitory program can improve students' spiritual intelligence because it consists of attitude development activities, dhikr therapy, and good habits. Spiritual Intelligence merupakan salah satu dari ketiga jenis kecerdasan yang meliputi Intelectual Quotient (Kecerdasan Intelektual) dan Emotional Quotient (Kecerdasan Emosional). Ma’had Al-Jami’ah IAIN Palangka Raya merupakan lembaga pendidikan yang termasuk dalam Unit Pelaksana Teknis (UPT) yang ada di kampus IAIN Palangka Raya yang bertujuan untuk menjadi Support Syestem dalam pembentukan karakter mahasiswa yang agamis, religius dan berwawasan luas. Artikel ini dibuat bertujuan untuk mengetahui apa saja program yang diselenggarakan oleh pengurus UPT Ma’had Al-Jami’ah IAIN Palangka Raya dalam melatih Spiritual Intelligence Mahasantri Ma’had Al-Jami’ah IAIN Palangka Raya. Metode yang digunakan dalam penyusunan artikel ini adalah metode observasi dengan target mahasiswa PAI 2021 Rolling ke-1.  Hasil penelitian menunjukkan bahwa program asrama wajib dapat meningkatkan spiritual intelligence mahasiswa, karena di dalamnya terdapat kegiatan pembinaan sikap, terapi dzikir dan pembiasaan yang baik.
Аналіз динаміки та структури імпорту агропродовольчої продукції
Authors: Антонюк П. О. , Антонюк О. П. , Ступницька Т. М. , Баранюк Х. О.
Published: April 2022

Дана стаття присвячена дослідженню формування об’єму, динаміки, структури та причин зрос-тання вартості імпорту на основі використання методів економіко-статистичного аналізу. В роботі вка-зано, що головною причиною зростання об’єму і вартості імпорту являється диспропорція між низьки-ми темпами зростання вітчизняного виробництва продукції сільського господарства і харчової проми-словості та високими темпами зростання доходів населення, що постійно формує дефіцит товарів,який і покривається все зростаючими закупками з інших країн. Виконано аналіз товарної та географіч-ної структури імпорту по товарах чотирьох розділів продукції. Дослідження географічної структурисвідчить, що основними експортерами агропродовольчої продукції в Україні стали держави ЄС, якіповністю використовують умови зони вільної торгівлі з Україною і є головними постачальниками про-дуктів тваринного походження та готових харчових продуктів. Встановлено також, що імпорт з іншихрегіонів світу має місце переважно по продукції товарних груп і товарних позицій, для виробництваяких в Україні не існує необхідних умов, а організація такої діяльності може бути економічно недоціль-ною. У висновках представлено рекомендації стосовно можливостей скорочення імпорту головнимчином, за рахунок нарощування внутрішнього виробництва.
Стратегічні аспекти державного регулювання розвитку виноробної галузі України
Authors: Ніколюк О. В. , Агеєва І. М. , Коренман Є. М.
Published: April 2022

У статті представлено стратегічні аспекти державного регулювання розвитку вітчизняної вино-робної галузі: соціально-економічна політика: методи державного регулювання розвитку виноробноїгалузі, безпосередньо не пов'язані з даною сферою, однак впливають на ефективність його функціо-нування; захист інтересів суб’єктів виноробної галузі на внутрішньому ринку, постійне стимулюванняекспорту продукції виноробної галузі, сприяння формування єдиного на рівні країни ринку виноробноїпродукції, формування сприятливих умов для імпорту техніки та технологій, які забезпечують підви-щення рівня конкурентоспроможності внутрішніх виробників продукції виноробної галузі; модернізаціянормативно-правової бази функціонування виноробної галузі країни та її адаптація до європейськихстандартів; удосконалення суспільно-політичних відносин; забезпечення розвитку виробничої інфра-структури, що припускає виділення державних коштів на проведення заходів саме довгостроковогохарактеру (субсидій на будівництво необхідних господарських приміщень, сприяння створенню об'єд-нань та кластерних структур); розвиток інтеграційних процесів у виноробній галузі; сприяння активіза-ції інвестиційних процесів у виноробній галузі; регулювання раціонального використання природнихресурсів; регулювання й підтримка науково-дослідної діяльності.
Apelativos, silencios y olvidos en torno a los animales de los Beatos en la temprana historiografía artística del siglo XIX y de inicios del siglo XX
Authors: Consiglieri Nadia Mariana
Published: April 2022

Los animales fueron representados con creces en los Beatos, tanto en las miniaturas principales como en iniciales y marginalia. Sin embargo, los tempranos escritos, registros y catálogos que dan cuenta de la serie codicológica guardan importantes silencios al respecto. El coleccionismo, las exhibiciones y la necesidad de registrar y catalogar piezas del pasado medieval hispánico comenzaron no obstante a integrar determinadas menciones y juicios de valor disímiles. Este trabajo aborda y discute tanto las omisiones como los primeros intentos por comenzar a reconocer la fauna en los Beatos concentrándose en los discursos historiográficos artísticos del siglo XIX y de inicios del siglo XX.
Os eternos movimentos (in)disciplinares entre a História e as Relações Internacionais: a importância do pensamento histórico
Authors: Mendes Pedro
Published: April 2022

Este artigo analisa os fundamentos historiográficos e teórico-metodológicos da relação (in)disciplinar entre a História e as Relações Internacionais (RI). Por meio de uma interpretação historiográfica, identifica os principais movimentos de afastamento e aproximação da História face às RI. O artigo tem dois objetivos fundamentais. O primeiro é demonstrar que, embora a História tenha um papel central na imaginação teórica da disciplina das RI, sua importância foi variável e refletiu os diferentes momentos políticos e científicos do seu nascimento, autonomização e maturidade. O segundo é problematizar as pontes e fronteiras entre as duas disciplinas, sublinhando a importância que o pensamento histórico tem para a análise das relações internacionais. O seu principal argumento é que o retorno do pensamento histórico à disciplina das RI mitiga as limitações a-históricas e associais do neopositivismo dominante e aumenta a sofisticação da compreensão reflexiva do estudo das relações internacionais.
EDUCAÇÃO FÍSICA ESCOLAR RELACIONADA À SAÚDE: UMA REVISÃO DE ESCOPO DOS ESTUDOS NO BRASIL
Authors: Rosas Raschelle Ramalho , Oliveira Raquel Procópio de , Barbosa Filho Valter Cordeiro , Oliveira Victor José Machado de
Published: April 2022

Esta revisão de escopo objetivou mapear os estudos que abordam a Educação Física escolar e sua relação com a saúde no Brasil. Buscou-se por estudos em oito bases de dados eletrônicas que avaliaram as ações pedagógicas relacionadas a educação para a saúde na Educação Física escolar. O processo de seleção foi feito por pares independentes. Uma síntese temática foi adotada. De 2.157 títulos, 13 foram incluídos. Eles foram publicados entre 2007 - 2020, representam intervenções nas regiões Sul, Nordeste e Sudeste, com maior número ações na rede pública. As estratégias de intervenção destacam o trabalho teórico-conceitual que objetiva a mudança comportamental em relação a atividade física. Também há ações relacionadas ao protagonismo juvenil e comunitário. Destaca-se a necessidade de valorização do professor de Educação Física como mediador do processo educacional e que novos estudos considerem a relação Educação Física e saúde pelo prisma de sua complexidade, mormente, concebendo-a pelo seu caráter pedagógico.
Produção de procedimentos pelo SAMU 192 no Brasil: Performance, benchmarking e desafios
Authors: Malvestio Marisa Aparecida Amaro , Sousa Regina Márcia Cardoso de
Published: April 2022

Objetivo: Descrever e analisar a produção de procedimentos realizados pelas centrais de regulação e recursos móveis do SAMU 192 entre 2015 e 2019, segundo frequência, indicadores de base populacional e produtividade diária, estabelecendo um indicador de performance. Método: Estudo censitário, observacional descritivo, realizado com dados de produção, extraídos do Sistema de Informações Ambulatoriais, complementados com dados do Instituto Brasileiro de Geografia e Estatística e do Ministério da Saúde. Resultados: Os 116,8 milhões de procedimentos analisados decorrem de 28,5% de aumento no período enquanto a população coberta e os recursos móveis cresceram 9,7% e 14,4% respectivamente. Cada mil habitantes cobertos geraram 109,8 chamadas, resultando em 24,0 envios de recursos móveis anuais. Diariamente, unidades de suporte básico realizaram 3,3 atendimentos e 0,5 transportes, enquanto o suporte avançado realizou 2,7 atendimentos e 0,9 transporte. Conclusão: A produção de procedimentos excedeu o crescimento de população coberta, com variações entre estados, alta produção em áreas populosas, forte presença do suporte básico e elevação dos transportes, todavia a produtividade nacional mostrou-se inferior a internacional.
Prevalência e fatores associados ao Estresse Relacionado ao Trabalho e a síndrome de Burnout entre profissionais de enfermagem que atuam em oncologia
Authors: Sant'Ana Jéssica Cristini Pires , Santos Juliano dos , Meira Karina Cardoso , Silva Pedro Gilson Beserra , Oliveira Lannuzya Veríssimo e , Almeida Sheyla Gomes Pereira de , Pierin Angela Maria Geraldo
Published: April 2022

Objetivos: avaliar a prevalência e fatores associados ao Estresse Relacionado ao Trabalho e a síndrome de Burnout entre profissionais de enfermagem que atuam em oncologia. Métodos: trata-se de um estudo transversal realizado com 231 profissionais de enfermagem que atuavam em um Centro de Alta Complexidade em Oncologia da cidade do Rio de Janeiro, Brasil, no período de dezembro de 2013 a junho de 2015. O estresse relacionado ao trabalho foi avaliado por meio da Escala de Estresse no Trabalho e a síndrome de Burnout pelo Maslach Burnout Inventory. Resultados: a prevalência de Estresse Relacionado ao Trabalho de intensidade moderada/intensa foi de 75,8% e 38,9% dos profissionais apresentaram síndrome de Burnout. Observou-se aumento da prevalência do Estresse Relacionado ao Trabalho com o avançar da idade [40-49, RP:1,61 (IC95%:1,01-2,55) e ≥ 50 anos, RP:1,78 (IC95%:1,10-2,90)], com histórico positivo de acidente [RP:1,29 (IC95%:1,06-1,60)] e agressão física ou verbal [RP:1,50 (IC95%:1,24-1,82)] durante o trabalho hospitalar. A presença de síndrome de Burnout também esteve associada a essas variáveis, além de estresse autorreferido [RP:1,14 (IC95%:1,05-1,23)]. Conclusão: o Estresse Relacionado ao Trabalho e a síndrome de Burnout se associaram a antecedentes relacionados ao ambiente de trabalho e a idade, evidenciando variáveis comuns na ocorrência dessas comorbidades.
Öğretmen Adaylarının Bilgisayar Öz Yeterlik Algılarının ve E-Öğrenmeye Yönelik Tutum Düzeylerinin İncelenmesi
Authors: KILIÇ Mehmet Yaşar
Published: April 2022

Bu araştırmanın amacı, öğretmen adaylarının bilgisayar öz yeterlik algılarının ve e-öğrenmeye yönelik tutum düzeylerinin üzerinde etkisi olan farklı değişkenleri incelemek ve bu kavramlar arasındaki ilişkiyi belirlemektir. Bu bağlamda, çalışmada ilişkisel tarama yöntemi kullanılmıştır. Araştırmanın katılımcılarını 2020-2021 eğitim öğretim yılında Sivas Cumhuriyet Üniversitesi Eğitim Fakültesinde eğitim gören 314 öğrenci oluşturmaktadır. Verilerin analiz edilebilmesi için katılımcılardan elde edilen veriler SPSS 24 programı ile işlenmiştir. Araştırmada, katılımcıların “bilgisayar öz yeterlik” algılarının ve “e-öğrenmeye yönelik tutum” düzeylerinin “yeterli” seviyede olduğu sonucuna varılmıştır. Ayrıca araştırma sonucunda katılımcıların “bilgisayar öz yeterlik” algılarının ve “e-öğrenmeye yönelik tutum” düzeylerinin cinsiyetlerine, sınıf düzeylerine, bireysel bilgisayara sahip olma durumuna ve günlük internette zaman geçirme

durumuna göre anlamlı olarak farklılaştığı bulunmuştur. Diğer bir sonuca göre katılımcıların “bilgisayar öz yeterlik” ve “e-öğrenmeye yönelik tutum” düzeyleri arasında anlamlı bir ilişki olduğu ve katılımcıların bilgisayar öz yeterlik algılarının, e-öğrenmeye yönelik tutum düzeylerini anlamlı olarak yordadığı bulunmuştur.
8. Sınıf Matematik Dersi Öğretim Programı Etkinliklerinin Öğrencilerin Dönüşüm Geometrisi Ünitesindeki Kavramsal Gelişimlerine Etkisinin Değerlendirilmesi
Authors: AKPINAR Esin , EKİCİ Gulay
Published: April 2022

Bu araştırmada, 8. sınıf matematik dersi öğretim programı etkinliklerinin öğrencilerin dönüşüm geometrisi ünitesindeki kavramsal gelişimlerine etkisinin değerlendirilmesi amaçlanmıştır. Araştırmada boylamsal tarama modeli kullanılmıştır. Çalışma grubu, Ankara ili Mangaldağı Ortaokulu 8. sınıfta öğrenim gören 26 öğrenciden oluşmaktadır. Verilerin toplanmasında bağımsız kelime ilişkilendirme testi ve çizme yazma tekniği kullanılmış, seçilen öğrencilerle görüşme yapılmıştır. Çalışmada oluşturulan kategori ve alt kategorilere ait iç tutarlılık iki alan uzmanı tarafından sağlanmıştır. Kodlayıcılar arasındaki ortalama güvenirlik %91 olarak bulunmuştur. Verilerin analizi sonucunda belirlenen kelimelerden ders adı, matematik terimleri, geometrik terimler ve konu dışı kavramlar olmak üzere toplam 4 kategori oluşturulmuştur. İncelenen çizimler doğrultusunda; çokgen çizimleri, döngü çizimleri ve konu dışı çizimler olarak 3 kategori oluşturulmuştur. Veri toplanmasının son aşamasında öğrencilerle görüşme yapılmıştır.
Araştırmanın sonunda öğrencilerin dönüşüm geometrisi konusunu işlemeden önce konuyla ilgili kavram bilgilerinin olmadığı görülmüştür. Öğrencilerle yapılan görüşmelerde matematik dersinin kitaptan öğrenilmesinin zor olduğu ancak konu öğrenildikten sonra kitapta yer alan etkinliklerin yapılabileceği sonucuna ulaşılmıştır. Elde edilen bulgular ve öğrenci görüşlerinden anlaşılacağı üzere öğretmenlerin konuyu işlerken nasıl bir yöntem kullanmaları gerektiğine ve müfredattaki değişiklere yönelik önerilerde bulunulmuştur.
Kurumsal Yönetim Derecelendirmesi ve Pay Değeri İlişkisi: Borsa İstanbul Örneği
Authors: KÜÇÜKOĞLU Sami , İLTER KÜÇÜKÇOLAK Necla , KÜÇÜKÇOLAK Recep Ali
Published: April 2022

Bu çalışmanın amacı; Türkiye’de faaliyette bulunan Borsa İstanbul (BİST) Kurumsal Yönetim Endeksi (XKURY) içerisinde yer alan halka açık şirketlerin hisse senedi değerleri üzerinde kurumsal yönetim derecelendirme notlarının etkisini analiz etmektir. Bu kapsamda 2016-2020 dönemlerinde Kurumsal Yönetim Endeksinin içerisinde yer alan firmaların, derecelendirme notları belirlenmiştir. Araştırma yöntemi olarak Eşleştirilmiş Bağımlı Örneklem t-Testi’nin kullanıldığı çalışmada derecelendirme notların açıklandıkları tarihlerden otuz gün önce ve otuz gün sonra zaman aralığında kalan tarihlerde oluşan hisse değerlerinin farkları incelenmiştir. Elde edilen sonuçlara göre 2016, 2017 ve 2019 döneminde kurumsal yönetim ilkelerini uygulayan şirketlerin hisse senedi değerleri üzerinde istatistiki olarak anlamlı bir etki olduğu görülürken, 2018 ve 2020 yıllarında makro düzeyde meydana gelen sistematik riskler nedeniyle bu yıllar için istatistiki bakımdan anlamlı bir etki görülememiştir.
Metagenomic extraction of high molecular weight plankton from filters v1
Authors: Vacherie Benoît , Labadie Karine
Published: April 2022

Filtration and extraction protocol of plankton metagenomic samples to obtain high molecular weight DNA for sequencing on Minion nanopore. The protocol describes the following steps: - filtration of the water on filters of different porosity - Recovery and grinding of organisms - HMW extraction - Results
RNAscope spatial transcript imaging in fresh-frozen mouse and human liver tissue v1
Authors: Decker Aubrianna , Stockwell Brent
Published: April 2022

We captured transcript distributions of select liver cell marker genes via in situ hybridization of specific targeting probes with the RNAscope Multiplex Fluorescent v2 Assay Protocol optimized for fresh-frozen samples. Our modifications to the commercial protocol included using half-concentration wash buffer (0.5X) for all wash steps downstream of probe incubation, and excluding the recommended protease step entirely. In mouse liver tissue, we spatially detected the transcripts for, ALB (Albumin), GLUL (Glutamine synthetase), and PTPRC (Protein Tyrosine Phosphatase Receptor Type C), and in human liver tissue, we spatially detected transcripts for GLUL, CD68 (Macrophage Antigen CD68), and LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1).
In Vivo GCase Activity Assay v1
Authors: Smith Laura
Published: April 2022

Assay uses the substrate PFB-FDGluc (5-(Pentafluorobenzoylamino)Fluorescein Di-β-D-Glucopyranoside)from ThermoScientific (Cat# P11947). Substrate is supposed to be taken up by late endosomes and lysosomes only and fluoresces green when cleaved by lysosomal GCase. Described by Mazzulli et al., J Neurosci. 2016 Jul 20;36(29):7693-706.
In Vitro B-galactosidase and B-hexosaminidase Activity Assay (Total Cell Lysate) v1
Authors: Smith Laura
Published: April 2022

Synthetic substrate can be used at acidic pH (pH 4.1) to assess activity of lysosomal hydrolases, β-Galactosidase and β-Hexosaminidase. The substrate is cleaved by β-Galactosidase and β-Hexosaminidase and produces a fluorescent product proportional to activity.
In Vitro GCase Activity Assay (Total Cell Lysate) v1
Authors: Smith Laura
Published: April 2022

Taurocholate inhibits the cytosolic B–glucosidase (GBA2) and activates lysosomal B–glucosidase (GBA1, a.k.a glucocerebrosidase (GCase)).In cultured cells the pH optimum is increased in the presence of taurocholate.Cultured cells are assayed without taurocholate at pH 4.5 and with taurocholate at pH 5.4.In normal controls and heterozygotes the B-glucosidase activity in the presence of taurocholate is approximately 2-10 times higher than without taurocholate.In cases of Gaucher disease the -glucosidase activity may be lower in the presence of the taurocholate.However, in fibroblasts there can be as much as a threefold increase in activity but the specific activity is very low compared with controls and heterozygotes. At acid pH B–glucosidase hydrolyses the substrate 4–methylumbelliferyl–B–D–glucopyranoside to 4–methylumbelliferone and glucose.Adding alkaline buffer stops the enzyme reaction and causes 4–methylumbelliferone to fluoresce at a different wavelength from unhydrolysed substrate, thereby permitting its measurement in the presence of a vast excess of unhydrolysed substrate.
[RETRACTED] Xp Nutrition Keto ACV Gummies - [Shark Tank] Is It 100% Effective and Proven Formula? v1
Authors: H H
Published: April 2022

[RETRACTED]

public grants to fund it's efforts, which we will discuss in the final section of this paper.
[RETRACTED] Keto Extreme Fat Burner South Africa: Does It Really Work Read Reviews? v1
Authors: legit scam
Published: April 2022

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The pill is most effective when you take ketogenic foods and snacks with the supplement.
KI-basierte Identifikation von Steckverbindern
Authors: Beyer Oliver , Wedel Andreas
Published: April 2022

Der Artikel beschreibt eine Methode zur automatischen Generierung des Digitalen Zwillings von Steckverbindersystemen – mit dem Ziel, bestehenden Herausforderungen für die Produktion durch die  Digitalisierung zu begegnen. Es wird ein System vorgestellt,das mithilfe einer hierarchischen und Deep-Learning-basierten Objekterkennung die Identifikation von  Komponenten und deren spezifischen Merkmalen ermöglicht. Die erkannten Komponenten werden in dem System mit dem semantischen Wissen des Unternehmens verknüpft – und der Digitale Zwilling des Steckverbinders abgeleitet. Final wird ein Verfahren vorgestellt, bei dem synthetische Daten für das Training von Netzwerken zur Objekterkennung genutzt werden. In der Praxis ergebensich dadurch Möglichkeiten der Kostenreduktion. Die Optionen werden anhand von bereits durchgeführten Experimenten diskutiert.
Por qué tu coño te parece feo
Authors: Luna Cristina
Published: April 2022

Este documento recoge un análisis sobre el tabú en nuestra sociedad, y cómo este afecta a la percepción estética que tenemos, en primer lugar, de nuestros cuerpos, siguiendo por el desnudo humano y llevándola a otros ámbitos. En este trabajo se parte de plantear qué es el tabú, su origen y los campos principales en los que se desarrolla, para llevarlo a la estética filosófica, a nuestro sentido cultural de lo “bello”, y a nuestra percepción de la identidad y la belleza. El tabú tiene un fuerte componente sociocultural, como agente y producto de la cultura. La estética, a su vez, está estrechamente ligada a la cultura, y por ende, al tabú, y no se puede analizar, de una forma holística, sin tener en cuenta el contexto que sustenta esa percepción.
Unlocking Grey Scientific Data on Resident Behaviour to Increase the Climate Impact of Dutch Sustainable Housing
Authors: Sanders Fred , Overtoom Marjolein
Published: April 2022

A “community of knowledge” of representatives of the housing sector in the Netherlands investigated the impact of the behaviour of residents in sustainable housing, both newly constructed and renovated stock. For this, grey scientific data were used, i.e., data and reports from non-university agencies reflecting research commissioned by civil society NGOs and commercial enterprises. The aim was to find perspectives for action (practical “rules of thumb”) to increase the impact of sustainable housing on CO2 reduction and facilitate the implementation of the Dutch national sustainability program. First, a conceptual framework and research model were created to generate the relevant research questions for the sustainable construction sector. An innovative research approach was used where data from academic non-university researchers were enriched by university academic researchers. Experiences with the methodology used are: (a) It implicitly places the many factors that influence sustainable resident behaviour in context; and (b) it makes clear that data from such research can complement university research with useful data from practice, data that are scientifically difficult to use because they are mostly derived from stand-alone case studies. The perspectives for action that were generated are: (a) Sustainable technologies must add new useful functionalities for acceptance; (b) sustainable supply must be tailor-made because households differ and tenants behave differently from homeowners; (c) decision-making about sustainable investments is not only based on financial factors; (d) residents are reluctant to become involved, so it is important that (e) the people representing contractors should be reliable; and (f) people want personalised plans and on-time delivery. Finally, the collected reports turned out to be focused on practice and therefore provided less theoretical information about the rebound effect.
Residents’ Perceptions of a Smart Technology Retrofit Towards Nearly Zero-Energy Performance
Authors: Mooses Veronika , Pastak Ingmar , Kamenjuk Pilleriine , Poom Age
Published: April 2022

Coping with global climate challenges requires changes in both individual practices and the technical infrastructure in which people operate. Retrofitting existing buildings with smart and sustainable technologies shows the potential in reducing the environmental impacts of the housing sector and improving the quality of life for residents. However, the efficiency of these means depends on their individual and societal acceptance. This calls for the need to incorporate social practice theories into the discussion of smart cities and technology adoption. This study aims to understand how smart retrofit intervention in an extensive pioneering smart city project in Estonia is perceived among the residents with different dispositions towards the environment and technology in an early phase of the intervention. We interviewed the residents of 18 Soviet-era apartment buildings which underwent a complete retrofit into nearly zero-energy buildings equipped with smart technologies. The results showed that pro-technology residents expressed high interest and trust towards smart retrofit intervention, while residents with environmentally inclined dispositions conveyed more critical arguments. This indicates that individuals’ underlying dispositions may result in different social practices and that a diverse set of engagement approaches are crucial for the success and social acceptance of large-scale pioneering projects in the housing sector.
Concerns of Owner-Occupants in Realising the Aims of Energy Transition
Authors: Oostra Mieke , Nelis Nelleke
Published: April 2022

Although there is an array of technical solutions available for retrofitting the building stock, the uptake of these by owner-occupants in home improvement activities is lagging. Energy performance improvement is not included in maintenance, redecoration, and/or upgrading activities on a scale necessary to achieve the CO2reduction aimed for in the built environment. Owner-occupants usually adapt their homes in response to everyday concerns, such as having enough space available, increasing comfort levels, or adjusting arrangements to future-proof their living conditions. Home energy improvements should be offered accordingly. Retrofit providers typically offer energy efficiency strategies and/or options for renewable energy generation only and tend to gloss over home comfort and homemaking as key considerations in decision-making for home energy improvement. In fact, retrofit providers struggle with the tension between customisation requirements from private homeowners and demand aggregation to streamline their supply chains and upscale their retrofit projects. Customer satisfaction is studied in three different Dutch approaches to retrofit owner-occupied dwellings to increase energy efficiency. For the analysis, a customer satisfaction framework is used that makes a distinction between satisfiers, dissatisfiers, criticals, and neutrals. This framework makes it possible to identify and structure different relevant factors from the perspective of owner-occupants, allows visualising gaps with the professional perspective, and can assist to improve current propositions.
Reusing Timber Formwork in Building Construction: Testing, Redesign, and Socio-Economic Reflection
Authors: Pronk Arno , Brancart Stijn , Sanders Fred
Published: April 2022

In 2018, the construction sector was responsible for 39% of the worldwide energy and process-related carbon dioxide emissions (Global Alliance for Buildings and Construction et al., 2019). This is partly due to the embodied carbon, which represents the carbon emissions related to building construction and material production (LETI, 2020). While zero energy buildings and zero energy renovations start to get the operational carbon down, the circular economy aims to do this by closing material loops and stimulating the reuse of discarded materials in building construction (Ellen McArthur Foundation et al., 2015). Although it is not a new phenomenon, material reuse does require a substantially different approach and is at this point not yet common in the building industry. This is especially true for load-bearing components. This article presents a pilot project for the reuse of discarded timber formwork for the construction of the façade and (load-bearing) substructure of a new house. Through this pilot case and by reflecting on a series of similar cases, it studies the remaining challenges for material reuse but also proposes and assesses redesign strategies that will allow upscaling the reuse of timber formwork. The project shows that although waste, material, and money can be saved by using reclaimed materials, it does complicate the design and construction process and, as such, does not necessarily reduce the total project budget. Moreover, for reuse to become a current practice, new design approaches and collaborations will need to be established. Finally, socio-economic factors must be considered to increase the acceptance of reclaimed materials in new building construction.
Lessons From EU-Projects for Energy Renovation
Authors: Van der Schoor Tineke
Published: April 2022

There is an urgent need for energy renovation of the existing building stock, in order to reach the climate goals, set in Paris in 2016. To reach climate targets, it is important to considerably lower energy demand as well as switch to fossil-free heating systems. Unfortunately, renovation rates across the EU remain at a low level of 1% per year. Deep renovation, which lowers energy use with 60% or more, accounts only for 0,2% of renovations. The heating transition thus progresses much more slowly than the electricity transition. We draw on the framework of technological innovation systems, which allows comparison of different transitions. In the literature, it is argued that the configurational nature of the renovation system is one of the main reasons for the slow heating transition. The renovation system is context-bound and consists of many actors both on the demand-side and the supply-side, which leads to a fragmented market. For increasing the speed of the heating transition, it is deemed important to counter this fragmentation. We carried out a review of reports and publications of EU-funded projects on energy renovation. In many projects fragmentation in the building sector was identified as one of the main obstacles. We analyzed the deliverables of these energy renovation projects to find tried and tested solutions. One of these is the so-called one-stop-shop, which promises to improve the organization of the supply side, while also providing an appropriate and affordable solution to the customer. In the discussion we argue that the energy renovation system could be improved by increasing collaboration on the supply side and at the same time simplifying the renovation process for customers. A promising tool to make this happen is the one-stop-shop.
Percutaneous laser nucleoplasty at lumbar level: Literature review
Authors: Beloborodov V. A. , Stepanov I. A.
Published: April 2022

The purpose of the study – to present an analysis of clinical trials to study the clinical efficacy and safety of the technique of percutaneous laser decompression of intervertebral discs based on a review of Russian and foreign studies.

The review article presents modern literature data covering the issues of indications, contraindications, technique, efficacy and safety of percutaneous laser disc decompression in patients with degenerative disease of the lumbar intervertebral discs. The publication present modern data on the choice of the most rational tactics for surgical treatment of patients with this pathology. Relevant, unresolved issues are indicated, which dictates the need for large randomized placebo-controlled clinical trials, with the inclusion of the latter’s results in systematic reviews and meta-analyzes.
Professor R. U. Umakhanov and the development of neurosurgery in Dagestan in the second half of the 20th century
Authors: Abusueva B. A. , Manyshev S. B. , Manysheva K. B.
Published: April 2022

Introduction. The first surgical operations on the nervous system in Russia began to be carried out at the end of the 19th century. The first neurosurgical clinic in Soviet Russia was opened in Petrograd on the basis of the trauma institute in 1921. In the late 1920s the Department of Neurology and Neurosurgery began to function at the Faculty of Medicine of North Caucasian Medical State University in Rostov-on-Don. During the Great Patriotic War, neurosurgery took shape as an independent scientific and clinical discipline.

Aim – to present the biography of the famous Dagestan neurosurgeon, doctor of medical sciences, professor Rashidbek Umakhanovich Umakhanov (1925–2003).

Materials and methods. On the basis of archival materials from the funds of the State Archives of the Russian Federation, the Central State Archives of the Republic of Dagestan, the archive of the Dagestan State Medical University, which are for the first time introduced into scientific circulation, the main milestones in the life of R. U. Umakhanov and his multifaceted activities in Dagestan.

Results. During the period of active work of R. U. Umakhanov, the formation of the neurosurgical service of the republic, the beginning of the systematic teaching of the discipline at the Dagestan Medical University and the folding of the system of rendering neurosurgical care to patients took place. A special place is given to the role of R. U. Umakhanov in the development of the clinic of neurology and neurosurgery, the main directions of scientific research of the scientist are considered.

Conclusions. The neurosurgical service in Dagestan began to develop at a time when doctors did not have diagnostic methods that are considered commonplace today. А neurosurgeon was armed exclusively with his own knowledge and could rely only on professional instinct. And at the origins of the provision of specialized care was Rashidbek Umahanovich Umahanov was a man who embodied the faithful to the chosen path, the scientific vision and aspirations for the future.
Shining «Moon», Sparkling «Thunder»
Authors: Tardivo G.
Published: April 2022

Knowledge of the past is always partial and shallow. The glottological research exposed in this article is an attempt to dust off the forgotten past and how languages evolved throughout the time. Any civilization idolizes the planets, especially the moon. On this occasion, Earth’s satellite name in the Greek language bears – at the end – a substrata word. Further, the «fire» concept of the Daghestani languages sparkled in the Aegean Sea. The article includes all the aspects, from the «fire» as a word root to the spatial-chronological application in a cross linguistic-cultural perspective, nevertheless, the ritual vision of the fire is also included.
Perception of the F.M. Dostoyevsky’s Works in the Serbian Literary Space
Authors: Nikanorova O.N.
Published: April 2022

The article presents a brief overview of studies on the work of the great Russian writer F.M. Dostoevsky. We are talking about works whose authors are representatives of Serbian scientific and theological thought. The paper traces the main stages of turning to the work of F.M. Dostoevsky in Serbia against the background of the historical development of Serbian literature and literary science.
Comment on “The 373 B.C. Helike (Gulf of Corinth, Greece) Earthquake and Tsunami, Revisited” by
Authors: Katsonopoulou Dora , Koukouvelas Ioannis
Published: April 2022

We are writing this comment because the presentation and the conclusions reached by Stiros (2022) regarding the catastrophic Helike earthquake of 373 B.C. neglect significant historical sources and scientific data from longstanding geoarchaeological work and excavations in the Helike region and offer an incomplete picture of the knowledge acquired about this famous earthquake of Classical Greece. In particular, the attempted re-examination of ancient sources is incomplete and subjective, serving the author’s a priori view that accounts of the 373 B.C. earthquake are later fabrications from Roman times. To this end, Stiros neglects published archaeological data dated from soon after the 373 B.C. catastrophe and wrongly concludes that the area did not experience repeated earthquake phenomena. Furthermore, his proposal that the Helike and Aigion faults are identical is an evident geological error. Instead, the two faults are 5 km apart, and their seismological evolution and tectonic geomorphology are quite different.
Comparison of the Photocatalytic Degradation of Congo Red Dye Using NiO and NiO-NiFe2O4 Composite
Authors:   the Department of Chemistry, Universitas Sriwijaya, Ogan Ilir 30662, Indonesia, Hariani Poedji Loekitowati , Said Muhammad , Rachmat Addy , Nurmansyah Astri , Amallia Ra Hoetary Tirta
Published: April 2022

NiO and NiO-NiFe2O4, composite had been synthesized by the coprecipitation method and characterized using XRD, FTIR, UV-DRS, and SEM-EDS. The photocatalytic degradation performances of the photocatalyst were investigated using visible irradiation, in which Congo red dye was used as a model. The photocatalytic degradation process was assessed through three variables: the pH of the solution, Congo red dye initial concentration, and irradiation time. The removal efficiency of photocatalytic degradation of 98.45% was achieved using NiO-NiFe2O4 at a pH of 6, an initial concentration of the dye of 100 mg/L, and an irradiation time of 120 minutes was higher than that obtained using NiO, which was 78.5%. Pseudo-first-order was suitable to describe the kinetics of photocatalytic degradation of Congo red, with values of k = 0.0114 min-1 and t1/2 = 60.789 min using NiO as the photocatalyst, and with k =0.0225 min-1 and t1/2 = 30.8 min using NiO-NiFe2O4. The removal efficiency of the NiO-NiFe2O4 composite of consecutive reuse three-time was 98.45, 97.13, and 96.21%, while NiO was 78.30, 77.12, and 75.32%. Therefore, NiO-NiFe2O4 was considered more effective in reducing Congo red concentration than NiO.
Comparison of risk of malignancy indices in the preoperative evaluation of adnexal masses
Authors: Hegaab Hassan Mansour , El Sokkary Hossam , Abo Elwafa Reham , Elzeity Eman Salem
Published: April 2022

Background: An adnexal mass patient is a common cause of hospital admission. The differentiation between malignant and benign cases is an important step in the management of such patients. The risk of malignancy index (RMI) is a simple scoring system depend on ultrasound data, menopausal status and serum concentrations of CA-125 tumor marker and has a great value in differentiation between benign and malignant adnexal masses. 4 different types of risk of malignancy index are created. The objective of the study was to compare the diagnostic performance of the four malignancy risk indices in differentiating benign and malignant ovarian tumors.Methods: This prospective study was performed on 60 patients with an adnexal mass confirmed on vaginal ultrasound.Results: There was statistical significance difference between the 4 types of RMI in benign and malignant groups. RMI 1, RMI 2, and RMI 3 had nearly the same area under the ROC curve; however, at the cut-off of>58.41, RMI 3 was more sensitive and less specific than RMI 1 or RMI 2. The RMI 2 was the most specific in predicting malignancy in terms of area under the curve; however, there was no statistically significant difference in performance of RMI 2 and 4 in malignant group.Conclusions: RMI 1, RMI 2, and RMI 3 had nearly the same area under the ROC curve; however, at the cut-off of >58.41, RMI 3 was more sensitive and less specific than RMI 1 or RMI 2, on the other hand the most specific was RMI 2 more than the other 3 RMIs.
Conclusions of ten years of maternal death surveillance and response in the health district of commune V of Bamako, Mali
Authors: Traore Soumana O. , Amadou Bocoum , Fane Seydou , Ousmane Kante Ibrahim
Published: April 2022

Background: The purpose of this study was to report the findings of the local maternal deaths surveillance and response (MDSR) committee in the health district of Municipality V of the district of Bamako. Methods: It was a retrospective study over a period from January 2009 to December 2017. We have compiled all the findings of the local MDSR committee from the health district of Municipality V. The data was generated from the Local Health Information System (LHIS). We made a simple entry of text and tables using Word and Excel software. Results: During the study period, the maternal mortality ratio (MMR) was 219/100,000 live births. The study was about 140 cases of maternal deaths that occurred in health facilities. The middle age of the patients was 28.01 years. Most of the deaths occurred in the postpartum period, with 106 cases. In 92.12%, the deaths were from direct obstetric causes (DOC), including hemorrhage 70%, eclampsia 7.85%, obstructed labor 7.14%. Seven deaths (5%) were from indirect obstetric causes (IOC), including anemia 3.57% and malaria 1.73%. In 2.58%, the deaths were from undetermined causes. Deaths were preventable in 80%. The response included, among other things, the notification of cases and the implementation of the recommendations made. In 70% of cases, the recommendations issued were implemented. Conclusions:  The MMR remains high in Municipality V of the district of Bamako. These deaths were mostly from DOCs, with hemorrhage as the main cause. These deaths were mostly preventable.