bluuebunny/crossref_metadata_2025 huggingface dataset:
“Mujeres constructoras de paz” (MUCPAZ), un trabajo conjunto sociedad-gobierno
Authors: Morales Owseykoff Tamara , López Fernández Eira , García Gálvez Jorge Antonio , Delfín Pozos Flor Lucila
Published: February 2024

El artículo discute la "Red Mujeres Constructoras de Paz" (MUCPAZ), un proyecto enmarcado en las políticas públicas del Gobierno Federal, específicamente en el Plan Nacional de Desarrollo (PND) 2019-2024 y el Programa Nacional para la Igualdad entre Mujeres y Hombres (PROIGUALDAD) 2019-2024. El PND es un instrumento de planeación estratégica que establece políticas públicas y objetivos nacionales a mediano y largo plazo, y uno de sus ejes transversales es la igualdad de género. Por otro lado, PROIGUALDAD tiene como objetivo general promover la igualdad entre mujeres y hombres en todos los ámbitos de la vida pública y privada, asegurando el pleno ejercicio de los derechos de las mujeres y su empoderamiento económico, político, social y cultural. MUCPAZ es un proyecto que se enmarca dentro de las políticas públicas y los objetivos nacionales de México para promover la igualdad de género, prevenir la violencia y construir una sociedad más pacífica y justa.
El marco legal como instrumento para el fortalecimiento de los Programas de Vinculación Laboral en las IES, caso Universidad Veracruzana
Authors: Suárez Jasso Elsa , Ramírez Vázquez Yolanda , Franco Hernández Óscar Fernando
Published: February 2024

La crisis económica generada por la pandemia de COVID-19 produjo un alza en la tasa de desempleo, siendo el grupo de edad más afectado, el que va de los 15 a los 34 años, en el cual se encuentran la mayoría de egresados de las Instituciones de Educación Superior. Éstas cuentan con programas o acciones para vincular a sus estudiantes y egresados al mercado laboral, como sus propias Bolsas de Trabajo. Sin embargo, según datos de la Encuesta Nacional de Egresado solo el 10% de egresados logra conseguir su primer empleo a través de la Bolsa de Trabajo de la IES donde cursó sus estudios. Por lo anterior, resulta necesario encontrar la manera de fortalecer estas acciones, siendo una forma a través de reformas a la legislación federal, estatal o de la misma institución educativa, las cuales ayuden a generar condiciones para crear vínculos con el sector privado. Es así como esta investigación abarca la problemática del desempleo en los egresados de educación superior, las acciones y programas de las Instituciones que los ayudan a vincularse al sector laboral, para finalmente presentar un análisis propositivo a la legislación que puede ayudar a fortalecer estos programas, centrándose en la Universidad Veracruzana.
Los factores de riesgos psicosociales relacionales en las personas trabajadoras de las empresas salvadoreñas
Authors: Echeverría Carlos Alberto , Flores Marta Irene , Vaquerano José Adán
Published: February 2024

Ante la escasez de diagnósticos relacionados a la prevalencia de los factores y riesgos psicosociales en el ámbito laboral, se realizó el presente estudio con la finalidad de conocer la percepción de 224 personas trabajadoras salvadoreñas asociados al malestar relacional, haciendo uso de los instrumentos de Healthy Talent Model© y HTMetrics PCAS Tool©, desde un análisis descriptivo e inferencial a través de la prueba del Ji cuadrado que evidencian la prevalencia de los riesgos psicosociales de violencia personal, CABI y acoso psicológico-mobbing, a fin de concluir el tipo de intervención que debe ser abordada por los tomadores de decisión de las empresas, diseñando programas y/o estrategias de intervención preventiva y reactiva para mitigar la existencia de los riesgos psicosociales en los ambientes de trabajo.
La comprensión lectora como pervivencia del conocimiento
Authors: Castillo Hernández José Andrés
Published: February 2024

En la actualidad, la comprensión lectora en el contexto de las tecnologías de información y comunicación (TIC) representa un desafío histórico. A diferencia de la lectura en libros impresos, la comprensión en medios electrónicos carece de la interacción directa y tangible que ofrece un libro físico. Los e-books, omnipresentes en este entorno digital, adoptan la forma del dispositivo electrónico del usuario, ya sea una computadora personal, laptop, smartphone, tablet u otro. Esto implica una adaptación significativa, ya que la experiencia de lectura varía en términos de formato, volumen, aroma y textura. Para los estudiantes universitarios, cuya formación inicialmente se basa en el uso de libros impresos, esta transición puede resultar desafiante. El libro impreso ha representado durante mucho tiempo el aprendizaje, el conocimiento y la información. En contraste, el texto electrónico carece del aspecto social al que los lectores están acostumbrados. La comprensión lectora en este contexto se centra en el ajuste circunstancial, permitiendo a los estudiantes aplicar sus habilidades de manera efectiva en esta nueva realidad digital. Este proceso de adaptación es fundamental para resolver los desafíos que surgen en este entorno en constante cambio.
La ingeniería ambiental su aplicación y gestión de procesos para la prevención y control de los recursos naturales
Authors: Velásquez Camacho Leída Yamile , Castillo Hernández José Andrés
Published: February 2024

La ingeniería ambiental desempeña un papel crucial al comprender y regular el ecosistema y cómo interactúan los seres vivos con su entorno. Su desafío radica en diseñar herramientas y métodos para abordar los problemas ambientales, preservar los recursos naturales y fomentar un desarrollo económico y social sostenible. Este trabajo examina los peligros globales y la crisis ambiental en Colombia y América Latina, destacando investigaciones recientes entre 2017 y 2022. Se exploran metodologías, programas de educación ambiental, principios, análisis del comportamiento humano y organizacional, y el papel de la educación en la resolución de la crisis ambiental. Se promueve la adopción de nuevos modelos de desarrollo y normas para garantizar la sostenibilidad, con un enfoque en la conciencia integradora para reducir los daños ambientales. En Colombia, la ingeniería ambiental se enfoca en promover el desarrollo social, proteger el medio ambiente y beneficiar a la sociedad, basándose en la constitución nacional, leyes internacionales y una creciente conciencia colectiva que busca cambios de comportamiento, respeto y sostenibilidad en armonía con la naturaleza.
Presentación
Authors: Mendieta Muñoz Rodrigo
Published: February 2024

Presentación
Características empresariales y su influencia en la decisión de financiamiento durante la pandemia de Covid-19: Evidencia de empresas en Ecuador
Authors: Becerra Palacios Edgar Rolando , Rojas Luna Rosa V. , Arpi Chicaiza Jessica G. , Sánchez Jiménez Kevin W.
Published: February 2024

El financiamiento es relevante para afrontar las crisis empresariales, más aún luego de la pandemia por la COVID-19, por tanto, el objetivo del estudio es determinar la influencia de las características de las empresas y de los directivos de las organizaciones registradas en la Cámara de Comercio e Industrias de Azogues en la decisión de financiamiento adicional durante la crisis sanitaria, para lo cual, se aplica un cuestionario a 135 socios. Mediante el uso de correlación de Spearman y regresión logística binaria, se evidencia que las características de las empresas (sector económico, estructura legal, experiencia, número de trabajadores, paralización de actividades y estructura de capital) influyen parcialmente en la decisión de financiamiento adicional, dado que únicamente la estructura de capital tiene una relación positivamente significativa con la variable de tratamiento, mientras que las características del administrador (edad, sexo, nivel de educación y años de experiencia) no tienen ninguna influencia.
Razonamientos Legales de la Contratación Estatal en Colombia Contra la Corrupción
Authors: Mendoza Rangel Fabian Leonardo , Piñerez Flórez Miguel Antonio , Montes Montealegre Henry Ali
Published: February 2024

El presente artículo de investigación centra sus esfuerzos en comprender el efecto adverso de la corrupción dentro de la contratación estatal, situación que se está convirtiendo en una molestia para sociedad civil puesto que, repercute negativamente en el progreso de la nación. Se emplea la hermenéutica jurídica y documental como herramienta para interpretar con un sustento crítico las normas que regulan el proceder de la libre competencia y la defensa de los derechos colectivos promulgado en la Constitución Política de 1991, al revisar los fundamentos de la ley 80 de 1993 y las demás normas que delimitan la contracción estatal, las sanciones al corrupto y el sistema de divulgación SECOP necesario para darle seguimiento. Concluyendo en la necesidad de mantener un criterio asertivo entre los funcionarios públicos al momento de seleccionar un contratista, ya que el Estado posee grandes dificultades para estar vigilando el progreso de cada contrato en el país.
Baja disponibilidad de pesca en el norte del río Uruguay; mirada desde los pescadores artesanales
Authors: Pérez Alberti Jorge Martín , Morales Aguirre Silvia , Lagaxio Victoria , Bondarenco Mateo
Published: February 2024

La disponibilidad de alimentos se define como la cantidad suficiente de alimentos de calidad adecuada y culturalmente aceptables para la población de un país en un período determinado. En el caso de las ciudades del Litoral Norte del Río Uruguay, se observa una escasa disponibilidad en materia de pesca local. Los objetivos de esta investigación fueron analizar las causas de esta escasa disponibilidad a través de la opinión de los y las pescadores artesanales de la región, y las instituciones referentes. Se realizaron entrevistas semi estructuradas a pescadores artesanales y referentes institucionales de la región, así como a un representante del sector privado. La imposibilidad de los pescadores para dedicarse exclusivamente a la actividad; el destino exportador que tiene la mayoría de las capturas de la región; el bajo consumo a nivel nacional y la escasa demanda de las ciudades por pescado de río, fueron algunas de las causas enunciadas.
Una mirada al proceso de construcción de la Ley de Soberanía Alimentaria y Seguridad Alimentaria y Nutricional de Cuba
Authors: Mc´Comark Bequer Maritza de la Caridad , Cruz Legón Mayra , Garcia Brito Yelitza , Rodríguez Valdés Lizandra
Published: February 2024

Cuba enfrenta un contexto complejo para garantizar los pilares de la seguridad alimentaria y nutricional; producto de la crisis económica internacional, la utilización irracional de los recursos naturales y el impacto del cambio climático, la cual se acentúa con la carencia de recursos financieros y los efectos de la pandemia del coronavirus. Ante este escenario, el Estado y Gobierno cubanos apostaron por aprobar un Plan de Soberanía Alimentaria y Educación Nutricional y su instrumentación jurídica, la Ley Soberanía Alimentaria y Seguridad Alimentaria y Nutricional y su Reglamento. El presente artículo aborda el proceso de construcción de estas normas legales, las metodologías novedosas utilizadas para su elaboración, con una sistematización de las buenas prácticas y lecciones aprendidas en este proceso legislativo.
Utilização de guias cirúrgicos em implantodontia
Authors: Libarino Alex de Sousa , Andrade Isaque Cajaíba , Silva Vitor Rodrigues da , Guedes Antonio Carlos Lourenço , Santos Vinícius do Amaral , Macena Juliana Andrade
Published: February 2024

Objetivo: Descrever sobre os benefícios dos guias cirúrgicos para um posicionamento tridimensional dos implantes na cavidade bucal e comparar os guias 3D com os convencionais. Revisão bibliográfica: Em destaque os guias 3D são elaborados a partir dos exames clínicos, imagens tridimensionais e softwares capazes de otimizar o tratamento com implantes dentários. Além do mais, os guias convencionais produzidos a partir do modelo de diagnostico ainda são usados rotineiramente pelos implantodontistas, resultando também em reabilitações adequadas. Esse fluxo digital proporcionou maior agilidade e previsibilidade no processo de trabalho, facilitando também uma comunicação de forma clara e objetiva do cirurgião-dentista com os profissionais que atuam no laboratório, possibilitando a fabricação da peça protética após a avaliação criteriosa do Cirurgião Dentista. A realização desse trabalho digital, no entanto, depende primordialmente do exame clínico rigoroso. A anamnese efetuada de maneira eficaz é um método valioso para o conhecimento do estado de saúde do paciente. Considerações finais: No decorrer desta revisão, observou-se que o uso dos guias cirúrgicos na implantodontia tornou-se uma ferramenta promissora durante a inserção e angulação do implante dentário.
Patient-Reported Outcomes in Hematopoietic Stem Cell Transplant Recipients: Design, Implementation, and Pilot Results
Authors: Hayes Christi Ann , Van Citters Aricca D. , Zhao Wenyan , Caldon Kate L. , Coughenour Charlotte M. , Tosteson Tor D. , Tosteson Anna N. A. , Meehan Kenneth R.
Published: February 2024

Background: Patient-reported outcome measures (PROMs) offer a collaborative opportunity between the patient and the care team to improve the quality of care. Objectives: To define PROMs in patients receiving hematopoietic stem cell transplant (HSCT), a pre-visit questionnaire (PVQ) was developed, which included a single agenda-setting question, the PROMIS-29 survey, and the National Comprehensive Cancer Network (NCCN) Distress Thermometer (DT). Study Design: Patients completed the PVQ 1 month prior to transplant (baseline) and at 1, 3, 6, and 12 months following transplant. Results: Sixty-five patients (n = 27 allogenic; n = 38 autologous) participated. Survey completion rates were 95% at 1 month post-transplant, 74% at 6 months, and 65% at one year. One month following transplant, patients’ fatigue (P < .001) increased, while physical (P < .001) and social (P < .001) functions decreased. Each returned to baseline at 3 months (P < .001). Fatigue was more pronounced in allogeneic recipients (P = .017) and autologous recipients recovered physical function much sooner (P = .021). Conclusions: This study confirms the feasibility of capturing PROMs longitudinally in patients receiving HSCT and demonstrates significant changes in fatigue and physical and social functioning following transplant.
Competition around the valorisation of rosemary scrubland: the gap of Belassoued (Central Dorsal, Tunisia) as case study
Authors: ABDALLAH Hédi
Published: February 2024

La garrigue à romarin de la Trouée de Bel-Lassoued (Dorsale tunisienne) peut avoir des formes différentes qui s’échelonnent entre la pelouse et la forêt ; elle est le résultat de la dégradation de la pinède de pin d’Alep suite à une longue histoire d’anthropisation du milieu méditerranéen. La population locale l’a défrichée pour divers usages. Dans un milieu ouvert, marqué par un climat méditerranéen et un sol calcaire comme le cas de la Trouée de l’oued Bel-Lassoued, la garrigue s’enrichit en romarin. Dans cette région, où tous les indicateurs de développement économique et social montrent la baisse des revenus des habitants, la garrigue de romarin qui occupe de vastes étendues, constitue un pilier important pour l’économie paysanne. Les divers usages des ressources de la garrigue à romarin ont joué et jouent encore un rôle important dans la diminution du taux de chômage dans un milieu exclusivement rural. La valorisation de la garrigue à romarin est fortement dépendante de la pluralité des usages et avec le sens que donnent les acteurs à ce type de formation végétale. Cependant, la pluralité des intervenants dans la garrigue à romarin peut présenter des intérêts divergents. Ceci peut entrainer des conflits d’usage entre les usagers des ressources naturelles de ce milieu.
Inclusion d’un nouveau schéma de transfert radiatif dans le modèle MAR et validation sur la Belgique
Authors: GRAILET Jean-François
Published: February 2024

The MAR model (Modèle Atmosphérique Régional) is a regional climate model that has notably been used to study the evolution of the climate in polar areas thanks to its accurate modeling of precipitation and its full coupling to a snow model. Research involving MAR has however occasionally suffered from the limitations of its current radiative transfer scheme, the Morcrette scheme, notably used for the ERA-40 reanalysis (2005). Within MAR, this scheme tends to either underestimate or overestimate the surface downward radiative fluxes. To eventually overcome these limitations, this paper discusses the inclusion in the MAR model of ecRad, the current lattest radiative transfer scheme provided by the ECMWF. The year 2011 is simulated over Belgium by a modified version of MAR v3.13 embedding ecRad in order to validate it. The outputs of the modified MAR are compared both to observations collected by 17 Belgian weather stations in 2011 and to outputs of the standard MAR v3.13., i.e. running with the Morcrette scheme. Finally, various configurations of ecRad are also tested to assess their respective effects on MAR and the prospects they offer.
Le système de gestion de l’eau du sous-bassin versant de la Haute-Comoé à l’épreuve des multiples usages et de la pression foncière, Sud-Ouest de Burkina Faso
Authors: SODORE Abdoul Azise , OUANDE Moumouni , SOULAMA Tiécoura
Published: February 2024

In Burkina Faso, the Upper Comoé sub-basin has a high potential of water, useful for the development of the population's economic activities. These economic activities create the increase needs of water with conflictual relations between the users the last few decades. This study analyses the water resource management system in the face of the risk of community conflicts in the Upper Comoé sub-basin. The methodology integrates literature review, observation and mixed field surveys. The main results are that the driving force of water conflicts are the decrease of its available quantity, the increasing demand of users and land pressure. Indeed, there is a decrease of the quantity of estimated at 7,284,915 m3 (17%) compared to the total demand of the user groups (43,398,317 m3). The relics of riparian formations, once useful for protecting the banks of water surface, have regressed by 4.8% to the benefit of shrubby savannahs (0.9%) and rainfed crops (0.9%) between 1990 and 2020. This degradation of the flora of the banks, linked to the high demand for land, is perceived by 58% of the respondents. To fix the problem, the local communities have created Local water committees. These committees use a water allocation system. At this step, some improvements are necessary, but going from land restoration and riverbank protection actions, these Local water committees are already relevant actors for conflict prevention and equitable water sharing.
THE OUTDOOR SPACES OF THE LARGE ALGERIAN HOUSING ESTATES, FROM DISUSE TO APPROPRIATION?
Authors: GANA Fayssal , HADJIEDJ Ali , PIERMAY Jean-Luc
Published: February 2024

En matière d’habitat, depuis les années 1970, les autorités algériennes ont donné la priorité absolue à la construction de grandes quantités de logements sous la forme de ZHUN (Zones d’Habitat Urbaines Nouvelles), pour tenter de répondre à la très forte croissance urbaine. Dépourvus de statut et d’usage officiel, rarement aménagés, abandonnés par les gestionnaires, les espaces extérieurs sont bricolés avec de très faibles investissements par les résidents des immeubles voisins pour leurs besoins personnels, de loisirs, de rencontres, de commerce, de stationnement de véhicules. On s’interroge dans cet article sur les mécanismes de production de ces espaces extérieurs. L’article conclut à une série d’« absences », ou d’un grand déficit, d’investissements, d’acteurs – qu’ils soient officiels ou résidentiels - et de régulation, et en définitive d’une « absence » de transactions sociales et de « territoire ». L’étude a été effectuée dans les deux plus grandes ZHUN d’Alger, Bab Ezzouar et Ain Naàdja.
Controlling Associative Transcarbamoylation Reactions by Light in Dynamic Polyurethane Networks Using Reversible Spiropyran Photoswitches
Authors: Vozzolo Giulia , Elizalde Fermin , Ximenis Marta , Mantione Daniele , Aguirresarobe Robert , Sardon Haritz
Published: February 2024

Polyurethanes represent a versatile class of polymers and are one of the most employed in the thermoset market. However, due to their thermodynamically stable carbamate bond, they suffer from a lack of reprocessability, recyclability, and degradability, and are therefore usually discarded after use. Recently, transcarbamoylation in polyurethane thermosets has been demonstrated via associative exchange in the presence of a strong organic acid. Intending to introduce spatiotemporal control in the processability of polyurethane materials, in this work we investigate dynamic transcarbamoylation by the addition of a latent acidic catalyst into an aromatic and an aliphatic polyurethane network. We introduce three photoswitches based on merocyanine/spiropyran compounds which, upon exposure to visible light, undergo a reversible cyclization reaction, resulting in formation of strong acids. The use of such photoswitches prevents the presence of a permanent acidic species in the network, which would eventually lead to its degradation over time. Importantly, due to the reversible nature of the cyclization reaction, the release of the acidic catalyst is not permanent, as evidenced by stress relaxation measurements. Overall, the evidence of the light-induced, acid-catalyzed transcarbamoylation is supported by stress-relaxation, optical microscopy, and self-healing measurements.
A method for surface characterization using solid-state nuclear magnetic resonance spectroscopy demonstrated on nano-crystalline ZnO:Al
Authors: Konrad Wied Jan , Mockenhaupt Benjamin , Schürmann Ulrich , Kienle Lorenz , Mangelsen Sebastian , Glänzer Janin , Ribeiro Celinski Vinicius , Behrens Malte , Schmedt auf der Günne Jörn
Published: February 2024

Nano-scale zinc-oxide doped with aluminium ZnO:Al is studied by different techniques targeting surface changes induced by the conditions at which ZnO:Al is used as support material in the catalysis of methanol. While it is well established, that a variety of 1H and 27Al resonances can be found by solid-state NMR for this material, it was not clear yet which signals are related to species located close to the surface of the material and which to species located in the bulk. To this end, a method is suggested which makes use of a paramagnetically impregnated material to suppress NMR signals close to particle surface in the blind-sphere around the paramagnetic metal atoms. It is shown that it is important to use conditions which guarantee a stable reference system relative to which it can be established whether the coating procedure is conserving the original structure or not. This method, called Paramagnetically Assisted Surface Peak Assignment (PASPA), helped to assign the 1H and 27Al NMR peaks to the bulk and the surface layer defined by the blind- sphere of the paramagnetic atoms. The assignment results are further corroborated by the results from heteronuclear 27Al{1H} dipolar dephasing experiments, which indicate the hydrogen atoms are preferentially located in the surface layer and not in the particle core.
Functionalization and Structural Evolution of Conducting Quasi-One-Dimensional Chevrel-Type Telluride Nanocrystals
Authors: Ogura Kaleolani , Cordova Dmitri , Aoki Toshihiro , Milligan Griffin , Yao Ze-Fan , Arguilla Maxx
Published: February 2024

Interfacing organic molecular groups with well-defined inorganic lattices, especially in low dimensions, enables synthetic routes for the rational manipulation of both their local or extended lattice structures and physical properties. While appreciably studied in two-dimensional systems, the influence of surface organic substituents on many known and emergent one-dimensional (1D) and quasi-1D (q-1D) crystals has remained underexplored. Herein, we demonstrate the surface functionalization of bulk and nanoscale Chevrel-like q-1D ionic crystals using In2Mo6Te6, a predicted q-1D Dirac semimetal, as the model phase. Using a series of alkyl ammonium (—NR4+; R = H, methyl, ethyl, butyl, and octyl) substituents with varying chain lengths, we demonstrate the systematic expansion of the intra-chain c-axis direction and the contraction of the inter-chain a/b-axis direction with longer chain substituents. Additionally, we demonstrate the systematic expansion of the intra-chain c-axis direction and the contraction of the inter-chain a/b-axis direction as the alkyl chain substituents become longer using a combination of powder X-ray diffraction and Raman experiments. Beyond the structural modulation that the substituted groups can impose on the lattice, we also found that the substitution of ammonium-based groups on the surface of the nanocrystals resulted in selective suspension in aqueous (NH4+-functionalized) or organic solvents (NOc4+-functionalized), imparted fluorescent character (Rhodamine B-functionalized), and modulated the electrical conductivity of the nanocrystal ensemble. Altogether, our results underscore the potential of organic-inorganic interfacing strategies to tune the structural and physical properties of rediscovered Chevrel-type q-1D ionic solids and open opportunities for the development of surface-addressable building blocks for hybrid electronic and optoelectronic devices at the nanoscale.
The interplay of solvation and polarization effects on ion pairing in nanoconfined electrolytes
Authors: Fong Kara , Sumic Barbara , O'Neill Niamh , Schran Christoph , Grey Clare , Michaelides Angelos
Published: February 2024

The nature of ion-ion interactions in electrolytes confined to nanoscale pores has important implications for energy storage and separations technologies. However, the physical effects dictating the structure of nanoconfined electrolytes remain debated. Here we employ machine learning-based molecular dynamics simulations to investigate ion-ion interactions with density functional theory-level accuracy in a prototypical confined electrolyte, aqueous NaCl within graphene slit pores. We find that the free energy of ion pairing in highly confined electrolytes deviates substantially from that in bulk solutions, observing a decrease in contact ion pairing but an increase in solvent-separated ion pairing. These changes arise from an interplay of ion solvation effects and graphene's electronic structure. Notably, the behavior observed from our first-principles-level simulations is not reproduced even qualitatively with the classical force fields conventionally used to model these systems. The insight provided in this work opens new avenues for predicting and controlling the structure of nanoconfined electrolytes.
Microsphere Loaded Silver Compound for the Effective Management of Burn
Authors: A Chaithanya P , Aparna Ivon , Premaletha K , Sarath Chandran C
Published: February 2024

Burns are serious thermal injuries which require immediate care management and treatment to minimize possible infections mortality and morbidity. Conventional therapy leads to delayed healing trauma and further dehiscence of the wound.Aim of the study A more effective and cost efficient treatment strategy that helps in localization and controlled release of antibiotics is required. Particulate drug delivery systems like microspheres can be used as a carrier for the delivery of the drugs along with controlled input drug release retention and reduced systemic toxicity. Silver sulphadiazine SSD is a broad spectrum antimicrobial agent which acts against microbial proliferation. Materials and methods The study is an attempt to formulate and evaluate SSD loaded microsphere cream for topical application and controlled release of drug to the burns. Polymers like chitosan and sodium alginate were used for microsphere preparation. Results and conclusion FTIR studies proved that there were no interactions between the excipients. The pre and post formulation studies showed successful results with formulation containing 4 chitosan i.e. they produced controlled release in order to reduce frequency of application and systemic toxicity. FC3 passed all the tests and hence were found to be the best formulation.
A Study on Prescription Auditing and Patient Satisfaction in a Tertiary Care Teaching Hospital
Authors: Siva S , Pradhan Abhishek , S Numbear Varun
Published: February 2024

Quality of life can be improved by enhancing the standards of medical treatment that can only be assessed by prescription audit because it is based on documented evidences to support diagnosis treatment and justified utilization of hospital facilities. Prescription audit is important for health-care professionals health service managers patients and the public. It supports health care professionals in making sure that their patients receive the best possible care. In this background the present study was conducted in the tertiary care hospital of Father Muller Medical College Hospital Mangalore Karnataka India. This hospital was chosen as no previous study of this kind was conducted. To monitor the appropriateness of various parameters in prescription and analyse the patientsrsquo satisfaction in the pharmacy department. This prospective observational study was conducted during Sep 2017-Feb 2018.Prescriptions were collected from the hospital pharmacy. Superscription contains patient details with name age gender and date of prescription. Out of 750 prescriptions majority of scripts were not filled with date column 16 and also did not contain patient signature 93. During the satisfactory questioning with patients 55 of them were not satisfied with pharmacist dispensing care. But the overall service of the pharmacy staff to patients is high 98. Prescription audit is an important tool to improve the quality of patient care. Our conclusion ends with patients were highly satisfied with the pharmacy staff.nbsp
Evaluation of Anti-Diabetic Activity of Novel Bioactive Compounds of Carthamus Tinctorius Linn
Authors: Krupanidhi Alagilawadamathada , Prakash Dabadi , Jayamma Kulkarni
Published: February 2024

In the present study normal and alloxan-diabetic rats were used to evaluate the hypoglyceamic activities of the Carthamus tinctorius Linn extract and isolated compounds. Extraction of Carthamus tinctorius seeds has been carried out by supercritical fluid extraction. The obtained extract was subjected to column chromatographic separation using silica gel 100-200 and 60-120 mesh.The extracts and isolated fractions were subjected to phytochemical evaluation acute toxicity study and antidiabetic activity was performed in alloxan induced diabetic Wister albino ratsas per the OECD and CPCSEA guide-lines.The SCF extracts and fractions of seeds of Carthamus tinctorius Linn were estimated by in-vivo model and showed excellent anti-diabetic activity p le 0. 001HS.The result of FBS level was significantly decreased in SCFE of Carthamus tinctorius Linn and fraction CT1 when compared with control group The SCFE of seeds of Carthamus tinctorius Linn possess significant anti-diabetic activity in both type-I and type-II diabetes mellitus.nbsp
Correlation of the Solubility Parameter and Antibacterial Activity of Moxifloxacin
Authors: Kattalagere Maheswarappa Manjunatha , Thimmasetty Juturu , Singh Ranjeet , Nayak Nagar Shashank
Published: February 2024

An attempt is made to determine the solubility parameter of moxifloxacin HCl and to establish the correlation between solubility parameter and drug properties using different methods given in the literature. The solubility parameter of the drug was calculated by Hoyrsquos molar attraction constants and peak solubility technique. Saturation solubility values of the drug were determined in various solvent blends having solubility parameter values ranging from 8.9 to 20.7 H. The solubility parameter of drug was 11.46 H and 11.67 H from Hoyrsquos method and peak solubility method respectively. Minimum inhibitory concentration MIC and Zone of inhibition ZOI of the drug for E. coli S. aureus and S. Paratyphi-A were determined. MIC was maximum for the drug in solvent system having the solubility parameter nearer to that of the drug. Minimum ZOI was observed for the drug in solvent system having the solubility parameter nearer to the drug solubility parameter. Transport studies revealed that the drug rejection from the solvent blends was dependent on its solubility parameter. Correlation was observed between the solubility parameter of the drug and the properties namely solubility diffusion of the drug MIC and antibacterial activity. Thus the solubility parameter of the drug can be correlated with the antibacterial activity of drug which can be used as a model.
Development and In Vitro Evaluation of Mucoadhesive Buccal Gels of Betamethasone Sodium Phosphate
Authors: Vijaybhaskar Desai , Sidramappa Shirsand
Published: February 2024

Betamethasone sodium phosphate is a disodium phosphate salt of 21-phosphate ester of synthetic glucocorticoid Betamethasone is known to possess immunosuppressant anti-inflammatory and antifibrolytic properties. Hence was used in formulation and development of mucoadhesive buccal gel for the treatment of oral submucous fibrosis to facilitate local action and to increase patient compliance. Six formulations were prepared using two different polymers in variable proportions and were subjected for the screening of physicochemical parameters viz.-homogeneity grittiness viscosity spreadability extrudability mucoadhesive strength pH drug content uniformity in vitro drug diffusion IR spectral analysis and stability studies. Formulation F5 containing 1.25 carboxymethyl cellulose sodium and 1.25 hydroxypropyl methylcellulose resulted with highest drug release and better mucoadhesive strength as compared to the other formulations.
Formulation and Evaluation of Nanoparticles of Ketoprofen for Transdermal Delivery
Authors: Bukka Rama , Kumar Sah Bashant , Kotal Deep
Published: February 2024

In the present study nanoparticles of Ketoprofen for transdermal delivery were prepared and characterized. Nanoparticles were prepared by microemulsification and solvent evaporation method by using different oils at fixed ratio of surfactants and co-surfactant 18. Ethanol or acetone was used to dissolve the oils and 10 mg 20 mg 30 mg and 40 mg of Ketoprofen was added to each of the formulation. The prepared nanoparticles were evaluated for drug content particles size zeta potential and ex-vivo drug permeability. Oleic acid glyceryl monostearate GMS and cholesterol were used as lipids and span 60 and tween 80 were used as surfactant and co-surfactant respectively. Particle size was found to increase when lipid was changed from oleic acid to GMS and to cholesterol. The ex-vivo permeation study using porcine ear epithelium was carried out. Nanoparticles showed increased permeation when compared to pure drug solution of same concentration indicates oleic acid based nanoparticles open new and interesting perspective as a drug carrier.
An Overview of Formulation Strategies for Treatment of Depression with its Advance Devices
Authors: Ashwini D , Baby Beny , Mathews Rashmi , Rajarajan S , M Bhavyasree R
Published: February 2024

nbspDepression is a serious mental health condition that requires understanding and medical care. Providentially with early detection diagnosis and a treatment plan like medication psychotherapy and lifestyle choices can cure or compensate for the early signs and symptoms associated with depressive patients. The topic emphasizes on formulation specific for treatment of depression by transdermal drug delivery system and advanced devices. Current interest as focuses on drug formulation is still under research stages.
Novel Drug Delivery Systems to Enhance Oral Bioavailability and Their Evaluation
Authors: K Mishra Mahesh , Baby Beny , Rajarajan S , Kaphle Utsukta , Singha Kabita
Published: February 2024

This review is carried out to understand thedifferent drug delivery systems to enhancetheoral bioavailability of anti-diabetes drug. Diabetes Mellitus is a continual and metabolic issue known to humanity over 2000 years. Solid lipid nanoparticle is one of the Formulation which capable of enhancing oral bioavailability of anti-diabetes drug with less side effect and toxicities.The reasons for poor bioavailability are poor aqueous solubility first pass metabolism interaction with food and degradation in the GIT. Different Novel Formulation are used to improve drug bioavailability are Nanosuspension Microemulsion Solid lipid Nanoparticle Vesicular drug delivery system like Liposomes and Noisome. The evaluation and characterisation parameters for SLNs are Entrapment efficiency particle size zeta potential invitro release etc. Solid lipid nanoparticle formulation is very promising method to enhance the oral bioavailability of drug.
dimensão relacional da governança na regionalização em saúde
Authors: Da Silva Mariana , Farfan Barroso Priscila , Alves de quevedo André Luis , Fabiano Guimarães Cristian
Published: February 2024

O objetivo do presente estudo foi conhecer, a partir do olhar dos gestores de nível regional da Macrorregião de Saúde Sul do Rio Grande do Sul, quais são os elementos potencializadores e limitadores que impactam na governança regional, na dimensão relacional. Através de abordagem qualitativa foram realizadas entrevistas semiestruturadas com dois gestores regionais de saúde escolhidos intencionalmente pela sua trajetória no território. Como resultado, destacou-se a importância de gestores regionais de saúde que conheçam o Sistema Único de Saúde e a regionalização, que se entendam como parte do território e valorizem essa instância. O alto grau de comunicação e colaboração entre gestores regionais e municipais de saúde apareceu como um elemento facilitador da governança regional, assim como as reuniões itinerantes e os momentos informais. Por outro lado, a alta rotatividade de gestores emergiu como um limitador dos processos da regionalização, uma vez que a composição dos grupos de decisão influencia a dimensão relacional e reflete nas pactuações interfederativas. Os fenômenos micropolíticos encontrados constroem o cenário de pactuação e impactam no direcionamento das políticas públicas no território. Assim, a compreensão desses fatores relacionais pode ser uma ferramenta potente para nortear as estratégias de gestão e planejamento em saúde.
Impactos da pandemia de COVID-19 na gestão da assistência farmacêutica
Authors: Nascimento Silva Sarah , De Paula Cunha Gustavo
Published: February 2024

A pandemia de COVID-19 exige do poder público a adoção de várias medidas para preservar a saúde da população, demandando a reorganização de vários serviços, como a gestão da Assistência Farmacêutica (AF). O objetivo deste trabalho foi mapear os riscos que mais impactaram a gestão da AF nos primeiros anos da pandemia, gerando dados para orientar melhorias do serviço brasileiro. Os riscos foram identificados na literatura, descritos e classificados quanto ao potencial de afetar alguma das etapas do ciclo da AF segundo critérios objetivos fundamentados na atividade essencial de cada etapa. A análise situacional foi realizada por meio da aplicação da matriz SWOT nas etapas da AF que sofreram maior impacto dos riscos mapeados. Foram mapeados seis riscos advindos do cenário pandêmico, sendo as etapas de seleção e a programação as mais impactadas. O apoio e o fortalecimento de comissões técnicas e infraestrutura tecnológica, com o uso de dados para tomada de decisão e ações preditivas, são oportunidades de avanços gerenciais no contexto analisado. Reconhecer e realizar o planejamento da gestão AF, revendo cenários e redirecionando ações a curto e médio prazo, torna-se um instrumento estratégico e necessário para o enfrentamento das emergências em saúde.
Relatório anual de gestão
Authors: De Oliveira Amorim Guilherme , Martins da Paz Alcieros , De Lima Pires Caio , Elizabeth Márquez de Martínez Gerbi Marleny
Published: February 2024

Os conselhos de saúde, dispositivos de controle social pertencentes à sociedade civil organizada, atuam na formulação, no monitoramento e na execução da política de saúde. Possuem atribuições na fiscalização e na apreciação dos instrumentos de planejamento, como o relatório anual de gestão. Nesse cenário, o objetivo deste artigo foi analisar os pareceres conclusivos dos relatórios anuais de gestão feitos pelos conselhos municipais de saúde de Pernambuco. Trata-se de um estudo descritivo, exploratório e baseado em análise documental, tendo como fonte de dados os pareceres conclusivos, publicados pelos conselhos de saúde, em relação ao relatório anual de gestão. Com base na análise realizada, foram constatadas fragilidades na apreciação por parte dos conselhos, assim como foram identificados desafios na própria gestão em saúde dos municípios. Conclui-se que capacitações e a educação permanente são necessárias para conselheiros e gestores superarem tais fragilidades e desafios.
Medidas de resultados reportados pelo paciente nos cuidados de saúde primários
Authors: Silva Ribeiro Mariana , Carneiro Rua Cláudia , Miguel Faria Araújo Nuno
Published: February 2024

Os Patient-Reported Outcomes Measures (PROMs) fornecem a visão do paciente relativamente à sua qualidade de vida, funcionalidade, sintomatologia e satisfação com os cuidados de saúde. O presente estudo tem por objetivo identificar PROMs associados à realidade dos cuidados de saúde primários e perceber seus possíveis beneficios na prática clínica. Foi efetuada uma revisão integrativa da literatura de acordo com a metodologia PICO (População,Intervenção,Comparação,resultados),  nas bases de dados PubMed,NICE Guidelines Finder, The Cochrane Library, utilizando os termos MeSH patient reported outcomes measures e primary healtchare. Esta revisão integrativa seguiu as recomendações metodológicas dos autores Mendes, Silveira e Galvão. Após a leitura e análise dos artigos incluídos na revisão, verificou-se em Portugal escassez de investigação acerca dos PROMs em cuidados de saúde primários. No entanto, os PROMs poderão ser uma mais-valia, quando baseados na melhor e mais atual evidência disponível na promoção de cuidados centrados nos pacientes e melhoria da qualidade de cuidados prestados em cuidados de saúde primários.  Os Patient-Reported Outcomes Measures (PROMs) fornecem a visão do paciente relativamente à sua qualidade de vida, funcionalidade, sintomatologia e satisfação com os cuidados de saúde. O presente estudo tem por objetivo identificar PROMs associados à realidade dos cuidados de saúde primários e perceber seus possíveis beneficios na prática clínica. Foi efetuada uma revisão integrativa da literatura de acordo com a metodologia PICO (População,Intervenção,Comparação,resultados),  nas bases de dados PubMed,NICE Guidelines Finder, The Cochrane Library, utilizando os termos MeSH patient reported outcomes measures e primary healtchare. Esta revisão integrativa seguiu as recomendações metodológicas dos autores Mendes, Silveira e Galvão. Após a leitura e análise dos artigos incluídos na revisão, verificou-se em Portugal escassez de investigação acerca dos PROMs em cuidados de saúde primários. No entanto, os PROMs poderão ser uma mais-valia, quando baseados na melhor e mais atual evidência disponível na promoção de cuidados centrados nos pacientes e melhoria da qualidade de cuidados prestados em cuidados de saúde primários.
Educação e Organização em Saúde
Authors: Nunes Andre
Published: February 2024

Os dois primeiros artigos destacam a importância da educação continuada, trazendo à baila, a temporalidade do conhecimento. O primeiro, analisa a atuação dos conselhos municipais de saúde de Pernambuco e evidência que as capacitações e a educação permanente são necessárias para conselheiros e gestores. O segundo, estuda a configuração do trabalho dos farmacêuticos da Atenção Básica de Porto Alegre durante a pandemia de corona vírus.

O terceiro artigo original avalia a Programação Pactuada e Integrada (PPI) do componente hospitalar cirúrgico da 12ª Região de Saúde do estado de Pernambuco. Os achados sugerem que a PPI é importante instrumento de marco regulatório loco-regional, porém, não garante efetivamente o acesso aos diversos níveis de assistência do componente hospitalar cirúrgico. Na sequência, apresenta-se interessante pesquisa dedicada a conhecer e analisar a opinião de adultos sobre o SUS.O quinto artigo analisa a resposta da Rede de Atenção à Saúde no estado do Maranhão frente à pandemia de COVID-19.  Os resultados apontaram que a Rede de Atenção à Saúde organizou-se com foco na ampliação de leitos hospitalares e equipes de Saúde da Família. O sexto texto de pesquisa discute o atendimento humanizado em saúde, destacando que a atuação transdisciplinar e as relações horizontalizadas . O sétimo estudo analisa como a cultura organizacional influência no desenvolvimento e na implementação da gestão do conhecimento em organizações públicas de saúde.

O oitavo artigo mapeou os riscos que mais impactaram na gestão da Assistência Farmacêutica, nos primeiros anos da pandemia, gerando informações para orientar melhorias na gestão do serviço.O novo artigo revisa estudos sobre os Patient-Reported Outcomes Measures (PROMs). Os PROMs fornecem a visão do paciente relativamente à sua qualidade de vida, funcionalidade, sintomatologia e satisfação com os cuidados de saúde. Finalmente, um estudo teórico, analisa as Parcerias para o Desenvolvimento Produtivo (PDP).
Augmented reality and internet of things: A review of convergence, applications and challenges
Authors: Ushaa Eswaran , Vishal Eswaran
Published: February 2024

Augmented Reality (AR) overlays digital information and virtual objects on real environments to deliver enhanced, contextual experiences. Meanwhile, the Internet of Things (IoT) enables an ecosystem of interconnected smart devices and sensors. This paper reviews the synergistic integration of AR and IoT in developing next-generation intelligent systems and human-machine interfaces. A detailed analysis is presented on, integrating AR software with IoT devices and dataflows, enhanced visualization, training, navigation and contextual user experiences enabled by AR-IoT convergence, and key challenges around interfaces, latency, spatial registration, security, privacy and scalability. The use cases across manufacturing, healthcare and smart environments illustrate the transformational potential of AR and IoT. However, standardized interfaces, edge computing, tailoring security with usability, and responsible development focused on human benefits are crucial for realizing the promise of hybrid physical-digital ecosystems. This paper undertakes a systematic review of Augmented Reality (AR) and Internet of Things (IoT) convergence encompassing integration approaches, emerging use cases, and technical obstacles. A cross-disciplinary analysis strategy centered on real-world viability synthesizes opportunities and challenges for shaping responsible research directions across application domains.