bluuebunny/crossref_metadata_2025 huggingface dataset:
RELEVANCE OF OVARIAN PRESERVATION IN YOUNG WOMEN WITH EARLY-STAGE ENDOMETRIAL CANCER AFTER HORMONAL AND SURGICAL TREATMENT: A COMPREHENSIVE LITERATURE REVIEW
Authors: TAZHIBAYEVA K. , SADYKOVA A. , OLZHAEV S. , ADZHIBAEV B. , MUSSINA A. , KHASSANOVA M. , BAIMUKHAMETOV K. , АDIYEV M.
Published: April 2024

Relevance: Ovarian preservation in young women with early-stage endometrial cancer after surgical treatment has been conventionally associated with complications. Nevertheless, recent randomized studies suggest a different perspective.

The study aimed to clarify the occurrence of complications, in particular relapses, associated with ovarian preservation in young women after hormonal and surgical treatment for early-stage endometrial cancer.

Methods: The analysis included articles published in full text over the past 10 years. We identified relevant observations from studies using a comprehensive search in the following databases: PubMed, Medline, Embase, and Cochrane Library. The search strategy included terms related to endometrial cancer: premenopausal, young woman, endometrial cancer, ovarian conservation. The study followed the PRISMA guidelines for systematic reviews.

Results: A total of 178 articles were studied, of which 111 articles (literature reviews and meta-analyses) (62%) described the cases of ovarian preservation. Of these, 84 were excluded for various reasons; 29 eligible articles were included in this analysis. Notably, factors such as younger age (P<0.0001) >, later year of diagnosis (P=0.03), residence in Central and Southern Europe and the United States (P=0.02), and lower-grade tumors in Asian countries (P<0.002) > correlated with the desire of women to preserve their ovaries. The conducted literature review showed that ovarian preservation did not significantly affect cancer-specific survival (risk ratio (HR) =0.78, 95% CI 0.17-2.74) or overall survival (HR=0.78, 95% CI 0.24-1.75).

This study’s results remained practically unchanged even after excluding women after radiation and hormone therapy.

Conclusion: This literature review revealed no statistically significant difference in relapse-free survival between patients after ovarian preservation at stage IA and partially at stage II com-pared to those after bilateral salpingo-oophorectomy.
Hydrodynamic Characteristics of High-Voltage Electrochemical Explosion with Controlled Input of Electric Energy into the Discharge Channel
Authors: Vovchenko A. I. , Smirnov A. P. , Demidenko L. Yu.
Published: April 2024

Based on the results of the mathematical modeling and experimental studies of the hydrodynamic characteristics of a high-voltage electrochemical explosion with a controlled input of electrical energy into the discharge channel, а possibility of the targeted and operational control of the force effect on the treatment object during a controlled high-voltage electrochemical explosion is substantiated. It is shown that by varying the mass of the exothermic composition placed in the inter-electrode gap and the modes of introducing electrical energy into the channel of a high-voltage electrochemical explosion, it is possible to control its hydrodynamic characteristics, forming pressure waves in the medium with a rational spatiotemporal distribution, providing an effective force effect on the treatment object.
Simulation Modeling of the Primary Electric Field Characteristics at the Boundaries of a Liquid Metal Object Processed by Passing an Electric Current
Authors: Chestnykh N. V. , Ivanov A. V.
Published: April 2024

The paper proposes to use the method of dividing massive conductors into elementary cells to determine the distribution of the characteristics of the primary electric field at the boundaries of a liquid metal object processed by passing an electric current. Simulation modeling of the characteristics of the electric field in the melt during its treatment with a direct current by one current source or simultaneously by two using two-electrode and four-electrode systems, respectively, was carried out. It is shown that the distribution of potentials and currents at the boundaries of the container with the melt, depending on the type of the electrode system, has qualitative and quantitative differences, which determines their multivariance and makes it possible to find favorable conditions for the thermal force load of the processing object.
Influence of Magnetic Field, Electric Field, and Illumination Intensity on the Parameters of Recombination Waves in Silicon
Authors: Zikrillaev N. F. , Shoabdurakhimova M. M. , Kurbanova U. Kh. , Narkulov N. , Shakarov F. K.
Published: April 2024

The paper presents the results of experimental studies of self-oscillations of the current of the recombination wave (RW) type in silicon doped with impurity selenium atoms. Doping of silicon with impurity selenium atoms was carried out using a new developed technology, which allows the formation of nanoclusters of impurity selenium atoms in the silicon lattice consisting of Se2 and Se4 molecules, without erosion of the surface of the samples. Self-oscillations in the Si samples were detected at room temperature and at sufficiently low electric fields. The dependences of the RW parameters (amplitude and frequency) in the Si samples on the resistivity and concentration of the formed nanoclusters of selenium atoms, as well as on the influence of a magnetic field, which makes it possible to control the amplitude in the range of J = 10-5–5×10-3 A and the frequency of self-oscillations of f = 104–5×106 Hz. The mechanism of the observed RWs is explained by the formation of nanoclusters consisting of two (Se2) or four (Se4) selenium atoms in silicon, which leads to the formation of fluctuations (clusters) of the main charge carriers and their reaching contact when determining the magnitude of the applied constant electric field. A possibility of practical use of self-oscillations of current observed in silicon diffusion doped with selenium impurity atoms to create solid-state generators is shown.
The role of viral marketing relationship and customer reviews as mediating of consumer trust to purchase Indonesian products
Authors: Meitiana Meitiana , Kristinae Vivy , Sambung Roby , Alexandro Rinto
Published: April 2024

The aim of the research is to analyze the influence of viral marketing and customer reviews on purchasing decisions with consumer trust as a mediating variable. In marketing theory, purchasing decisions can be improved by mediating consumer trust, so that products can be sustainable. The study was conducted on Indonesian iced tea products, which are typical tea leaf products from Indonesia. The type of research used in this research is quantitative and analyzed using PLS. 105 respondents in the research were customers of Indonesian iced tea products in Palangka Raya City. The research results show that viral marketing, customer reviews mediated by consumer trust variables had a significant positive effect on purchasing decisions, viral marketing had a significant positive effect on purchasing decisions, viral marketing had a significant positive effect on consumer trust, customer reviews had a significant positive effect on purchasing decisions, customer reviews had a significant positive effect on consumer trust and consumer trust had a significant positive effect on purchasing decisions for Indonesian Iced Tea products in the city of Palangkaraya.
The effect of knowledge management on organizational performance in the service sector: The role of transformational leadership as the moderating
Authors: Alhawamdeh Hamzeh , Hijazi Haitham Ali , Fraihat Baha Aldeen Mohammad , Alhawamdeh Abbas Mohammad , Shiyyab Fadi Shehab , Al-Okaily Manaf
Published: April 2024

The main aim of the current study is to assess the relationship between knowledge management (KM) capabilities and organizational performance (OP) in developed nations. In addition, this study also aims to assess the moderating influence of transformational leadership (TL) between KM infrastructure (KMCI) and organizational performance (OP) of the Jordanian service and tourism sectors. In this study, it’s suggested that KMCI and its components will directly affect OP. In addition, it’s expected that TL moderates the relation between study variables. Purposive sampling was used to gather data from the service and tourism sectors in Jordan, as it is the population of this study. Partial Least Squares was used to analyze the data. The findings indicate that KMCI and its components significantly affect OP. TL moderated the effect of KMCI on OP. It is advised for decision-makers to concentrate on KMCI, create the proper culture and organizational structure, and improve its technologies to support the growth of KM activities in Jordanian service and tourism sectors.
The role of relational benefits and brand experience in forming customer perceived value and its impact on e-WOM and willingness to pay more
Authors: Tj Hery Winoto , Widjaja Bernard Tirtomoeljono
Published: April 2024

This research explores the mediating role of the value perceived and received by consumers (customer-perceived value) in the context of brand experience and relational benefits, as well as their impact on consumers' willingness to pay more. Additionally, this research investigates consumers' desires to share experiences via social media (e-WOM) when consuming these products and services with their relatives. Using a purposive sampling technique, we obtained responses from 256 consumers of fast-food restaurants spread across Jakarta. The research results prove that relational benefits and brand experience are important in building consumer perceived value, ultimately influencing the emergence of positive e-WOM and the willingness of fast-food restaurant consumers to pay more.
Does corporate governance affect corporate social responsibility?
Authors: Zureigat Bilal Nayef
Published: April 2024

This research aimed to examine the impact of corporate governance on the corporate social responsibility of the Jordanian companies listed on the Amman stock exchange. Using a dynamic panel system, the current investigation of 65 Jordanians uses GMM estimation for the years 2018 to 2022. Corporate social responsibility has been measured using a corporate social responsibility index. It has 84 items divided into four groups: employee activity items, environmental items, objects related to society and the items related to customers are in the last group. The study concluded that Jordan demonstrated a substantial level of corporate social responsibility in keeping with Jordan's expanding understanding of and practice of corporate governance. Specifically, this study indicated that board meetings, foreign ownership, and block holder ownership significantly influenced corporate social responsibility. Our study’s findings should interest policymakers as well as regulators in nations with similar business ownership and regulatory regimes. This study contributes to addressing an oversight in the literature on social responsibility studies as well as corporate governance characteristics. As a result, this paper provides useful information and insights for businesses and regulators seeking to increase the impact of social responsibility on their businesses through a focus on corporate governance excellence.
Value chain analysis and managing supply chain costs
Authors: Abdelraheem Abubkr Ahmed Elhadi
Published: April 2024

The study aimed to reveal the effect of value chain analysis (VCA) of internal and external activities to manage and reduce product costs along the supply chain (SC) in industrial facilities in the Red Sea State in Sudan from the point of view of managers, financial managers and accountants there, from the basic dimensions of value chain analysis represented by VCA of suppliers' activities, VCA for product design activities, VCA for production activities, and VCA for customer activities. The supply chain costs are defined in just-in-time (JIT), target costing (TC), and activity-based costing (ABC). The study revealed that analyzing VCA contributes to managing and reducing product costs along the supply chain by exploiting the interrelationships and overlap between the value chain analysis and the supply chain for each supplier's production and customer activities.
The mediating effect of crisis leadership and digital technologies on emergency supply chain capabilities of logistic companies
Authors: Wairisal Paulus L , Risambessy Agusthina
Published: April 2024

This research aims to analyze the relationship between crisis leadership and supply chain emergencies. The study also investigates the effect of digital technology on supply chain emergencies and the effect of digital technology on crisis leadership. The research method is a quantitative approach, research data was obtained by distributing online questionnaires via social media. There were 856 questionnaires distributed to logistics company managers and of the 856 questionnaires distributed, 426 respondents or 50% gave responses determined by the simple random sampling method. This research uses quantitative methods with data analysis using Structural Equation Modeling (SEM) through Partial Least Square (PLS) with data processing software, SmartPLS 3.0. The results of this research show that crisis leadership had a positive and significant influence on supply chain emergencies. Digital technology had a positive and significant influence on supply chain emergencies and digital technology had a positive and significant influence on crisis leadership. In addition, crisis leadership mediated the relationship between digital technology and supply chain emergency capability. Crisis leadership had a fully mediated nature. Crisis leadership encourages an increase in the relationship between digital technology and emergency supply chain capability. These findings create the view that the application of digital technology and crisis leadership can encourage improvements in emergency supply chains and provide direction to logistics company managers to use digital technology to improve supply chain capabilities in their companies. The findings of this research indicate that digital technology under the influence of crisis leadership significantly improves emergency supply chain capabilities.
Navigating uncertainty in global gas trading: Leveraging cost optimization models within supply chain dynamics
Authors: Dahan Abdulkarim A. , Alsmairat Mohammad A.K. , Alshami Mohamed A. , Altheeb Rasha A.
Published: April 2024

The impact of geopolitical conflict and supply chain (SC) uncertainties in the global gas trading context is a burgeoning area of research. The strategic imperative of optimizing resource and technology utilization through cost optimization models within SC dynamics is realized. This study examines the effectiveness of linear programming techniques in mitigating the transportation challenges in the landscape of global gas trade, particularly amidst geopolitical disruptions in the SC. Computational tests underscore the substantial efficiency gains provided by this method, highlighting its capacity to generate significantly more efficient solutions to transportation problems. The findings indicate that the model shows promise for practical implementation, showcasing a notable reduction in transportation costs across the three primary markets for liquefied natural gas (LNG). Significantly, this reduction surpasses a quarter of the original expenses, indicating the potential for substantial cost savings in turbulent geopolitical environments and uncertain SCs. This study emphasizes the pivotal role of cost optimization models in navigating uncertainty and enhancing efficiency within the intricate and volatile landscape of global gas trading supply chains.
How managers’ green transformational leadership affects green resilient supply chain: The moderating impact of green ambidexterity and green innovation
Authors: Purnomo Agus , Syafrianita Syafrianita , Simatupang Togar Mangihut , Mutalib Mohamed Ibrahim bin Abdul
Published: April 2024

Upstream textile companies in Indonesia are the most significant contributors to environmentally hazardous production waste. Green Transformational Leadership (GTL) is critical to achieving a Green Resilient Supply Chain (GRS) to address vulnerability to supply chain disruptions while maintaining environmentally friendly practices. In addition, the mediation of Green Ambidexterity (GAM) and Green Innovation (GIN) is believed to strengthen the achievement of GRS. In line with the Indonesian government's policy to protect the environment, this study examines the direct effect of green transformational leadership variables on a green resilient supply chain. It evaluates Green Ambidexterity and Green Innovation's mediating effect on the relationship between GTL and GRS. This study analyzes the data of 50 production managers of upstream textile companies from 87 respondents collected from the survey. The analysis uses PLS-SEM based on variance to verify the relationship between variables. The research results indicate that green transformational leadership significantly influences green resilient supply chains. It was found that both Green Ambidexterity and Green Innovation significantly influence the Green Resilient Supply Chain, both directly and through mediating effects. Therefore, managers should consider implementing a Green Resilient Supply Chain, Green Ambidexterity, and Green Innovation practices to improve organizational goals while maintaining a green environment.
The nexus between digital supply chain and sustainability: An empirical study in pharmaceutical companies in Jordan
Authors: Lemoun Amro Abu , Dellagi Hatem , Al-Daoud Khaleel , Abusalma Abdallah
Published: April 2024

This study focuses on the impact of the digital supply chain, including digital suppliers, digital manufacturing, and digital logistics, on sustainability outcomes in pharmaceutical companies in Jordan. Quantitative data were collected through a questionnaire distributed to a sample of 226 managers of pharmaceutical companies in Jordan. The questionnaire measures perceptions, attitudes and experiences related to digital supply chain adoption and sustainability performance. Structural equation modeling (SEM) was used as an analytical framework to study the relationships between digital supply chain and sustainability outcomes. The hypothesized relationships were tested using confirmatory factor analysis and path analysis techniques within the SEM framework. The results indicate a positive relationship between digital supply chain adoption and sustainability performance in pharmaceutical companies in Jordan. Based on the results, several recommendations were proposed for pharmaceutical companies in Jordan to enhance their sustainable performance through digital supply chain initiatives. This research contributes to the existing literature by providing empirical evidence on the relationship between digital supply chain practices and sustainability outcomes in the pharmaceutical industry, especially in the context of Jordan.
Adoption of information technology encourages the creation of innovation to improve industrial performance in the digital era
Authors: Yasa Putu Ngurah Suyatna
Published: April 2024

Technology is becoming a trend, so this research examines technology information as a driver of productivity for small or medium industries (SMEs). This research examines the impact of innovation on the performance of small and medium enterprises, the impact of information technology on industrial performance, and the role of information technology as a mediator of innovation on company performance. Data was collected through an online survey. The total population is 346, so that many questionnaires were distributed to MSMEs using path analysis and Smart PLS as processing tools. The findings are that innovation has an influence on increasing the productivity of small businesses, innovation has a positive role on information systems, remains insignificant on the performance of industrial Performance, and information technology does not mediate the relationship between innovation and performance. So it can be said that innovation plays an important role in improving company performance.
Profile of RT-PCR for SARS-CoV-2: A Preliminary Study from COVID-19 patients in Government Medical College and Hospital, Doda, Jammu and Kashmir
Authors: Akhtar Sameera , Akhter Sufhia , Ali Shoket , Bashir Imran
Published: April 2024

A new corona virus pandemic (COVID-19) has caused 7,010,568 deaths worldwide. The three stages of the Covid-19 disease course include the asymptomatic stage, upper respiratory tract infection, and lower respiratory tract infection/ARDS. Materials and methods: We examined the dynamical profile of SARS CoV-2 in 100 COVID-19-infected hospitalised patients from Jammu and Kashmir's Chenab valley (Doda, Bhaderwah, and Kishtwar). Patients' throat and nasal swab samples were taken at various times following the onset of symptoms. RT-PCR test with a COVID-19 nucleic acid detection was used to find SARS-CoV-2. The real-time RT-PCR assay examined two target genes: nucleocapsid protein (N) and open reading frame 1ab (ORF1ab). AIM: To assess the SARS-CoV2 positive detection rate using real-time polymerase chain reaction (RT-PCR). Results: At one week after the onset of symptoms, the PCR positivity rate was 100%; it then gradually decreased until it reached 100% negative results at six weeks following the onset of symptoms. Up to 6 weeks following the start of symptoms, viral shedding took place. For senior individuals, an extended monitoring period is required. Conclusion: This study discovered that individuals with extended viral nucleic acid conversion were typically older and had more co-morbid conditions, such as diabetes and hypertension.
Extrapolation Based Shelf Life Establishment of Sacubitril and Valsartan Floating Tablet as per ICH Q1e
Authors: Goyal Anil Kumar , Kumar Vinesh , Yadav Seema , Kumawat Radhey Shyam , Maheshwari Monika
Published: April 2024

According to ICH Q1A(R2) of Stability Testing, the purpose of stability testing is to establish a shelf life for drug product and recommended storage conditions. The aim of this research is to evaluate the shelf life of Sacubitril and Valsartan Floating Tablet using extrapolation on basis of data collected from Stability studies and Forced Degradation Studies. The RP-HPLC method to determine the drug content was validated as per guidelines of ICH Q2(R1). The parameter covered for validation were specificity, accuracy, method, precision and intermediate precision, linearity, all parameters achieved the results within predefined acceptance criteria. The Stability studies were performed on accelerated condition at 40oC±2oC/75%±5% and Long Term condition at 25oC±2oC/60%±5% for 6 months. Forced Degradation Studies were performed on Oxidation, Thermal, and Photolytic degradation for 5 days. Extrapolation was performed such that the extended retest period or shelf life was validated using Statistical tools for a future batch formulation for any industry with test results close to the release acceptance criteria. The drug product was unstable in open atmosphere as it failed drug content test with 96.79 % in oxidation degradationon 4th day. There was no significant changes observed in the stability studies and stability data was evaluated using extrapolation method and statistical tools. Hence, it was proved that the dosage form of Floating Tablet is stable at ambient temperature for estimated 12 months. These studies confirmed that physical and chemical stability of Sacubitril and Valsartan were enhanced in Floating Drug Delivery System. This research study can be fruitful and useful for researchers and pharmaceutical industries to acquire the technique and data of stability of drug product-Floating Tablet of Sacubitril and Valsartan.
Immunomodulatory activity of Anacardium occidentale L. in Laboratory animals
Authors: Bagwan Salma A. , Naikwade Nilofar S.
Published: April 2024

Aim: To study the phytochemical analysis and immunomodulatory activity of ethyl acetate extract of nut of Anacardium occidentale Linn. Methods: A laboratory based experimental method was used to evaluate immunomodulatory activity by dividing animals into six different groups, comprising six animals in each group. The immunomodulatory activities were determined by using carbon clearance test, delayed type hypersensitivity (DTH) test and In vivo antibody (HA) titer response to SRBCs. Result: The response produced by oral administration of ethyl acetate extract of nut of A.occidentale showed a significant dose dependent effect by increase in Phagocytic activity, DTH response and augmentation of humoral immune response to sheep red blood cells. Conclusion: Ethyl acetate extract of nut of A. occidentale showed a significant immunostimulatory effect on both the humoral and cell-mediated immune systems in the Wistar albino rats.
Estimation of First Line Anti-Tubercular Drugs resistance and their genetic analysis by Geno Type MTBDRplus assay from an Intermediate Reference Laboratory in Eastern Uttar Pradesh, India
Authors: Singh Nandini , Singh Amresh Kumar , Mishra Ashwini Kumar , Singh Narendra Pratap , Kumar Sushil
Published: April 2024

Globally, drug-resistant tuberculosis is major public health issue. Multidrug-resistant tuberculosis (MDR-TB), especially resistant to first line drugs (isoniazid [INH] and rifampicin [RMP]), is one of the serious health concerns in India. As per annual India TB report 2022, 2.7% of total TB patients were infected with MDR-TB. Line probe assay (LPA)/GenoTypeMTBDRplus technique based on polymerase chain reaction is a rapid method for the detection of RMP and INH simultaneously. This cross-sectional prospective study includes 405 samples from suspected TB patients from 30.12.2021 to 13.05.2022. Samples were received from linked districts with Intermediate Reference Laboratory (IRL) for fluorescent microscopy (FM) and LPA testing through proper cold-chain under NTEP program and then subjected to FM. Only smear positive sample were subjected to LPA as per manufacturer instructions. Out of 405, a total of 261 samples were smear positive (64.4%). Among 261 samples processed for LPA, 255(97.7%) showed valid result and 6(2.3%) were found invalid. In LPA result, 227 (89.01%) were susceptible to both INH and RMP, 9(3.5%) had MDR-TB, 18(7.05%) shows INH mono resistance and 1(0.3%) shows RMP mono resistance. Patients with MDR-TB were prominent in younger age group (Mean±S.D; 29.6±5.7 vs. 36.6±17.8 years, p value = 0.004). Prevalence of MDR-TB cases is higher in our study than cases reported in annual TB report (2022) of India. LPA is proved highly accurate in rapid detection RMP resistant/MDR-TB cases. Early diagnosis may potentially enable earlier commencement of appropriate TB drugs and the reduction of transmission of MDR-TB and may possibly leading to the complete eradication of TB in India.
Formulation and Wound healing activity of Nano Particle Emulsion Gel containing Nigella sativa seed oil in rabbits
Authors: Syapitri Henny , Panduragan Santhna Letchmi , Natarajan Satheesh Babu , Thaib Cut Masyitah , Agnes Purba , Sembiring Rinawati , Poddar Ruma
Published: April 2024

Black cumin (Nigella sativa) seed oil contains thymoquinone and saponins, can be used to treat inflammation. This study aims to obtain a nanoparticle emulsion gel preparation of black cumin seed oil that has anti-inflammatory activity of wound healing in rabbit experimental animals. The preparation was made with a gel base (F1), a gel formula with black cumin extract (F2), and a black cumin extract gel formula with nanoparticle emulsion (F3). Evaluation of the preparation was carried out for eight weeks, including pH, organoleptic, homogeneity, dispersibility, and stability tests. A particle size analyzer (PSA) test was carried out to assess the size of nanoparticles. The activity test was carried out by observing the wound. The results of the pH test of the three formulations in the normal skin pH interval are 4.5–6.5. The evaluation results of the three formulations showed they were stable. The results of the homogeneity test of the three formulations showed that the preparations were homogeneous during storage. The gel spreadability test is good, with a minimum and maximum range of 5 to 7 cm after being given a load of 150 g and a very comfortable semisolid consistency.
Therapeutic application of Lycopene in preventing Oral diseases- A Review
Authors: Umapathy Vidhya Rekha , MN Prabhu , S Bhuminathan. , Jaber Aesa Alzaroug
Published: April 2024

According to epidemiological statistics, eating a diet rich in fruits and vegetables can help prevent oral cancer in a variety of ways. Lycopene is a reddish-colored carotenoid found in abundance in tomatoes and other fruits and vegetables. It is reported to be beneficial in the treatment of chronic disorders such as cancer and cardiovascular disease. Hence, the objective of this study is to summarise the lycopene's features and analyse its potential function in the development and treatment of oral precancerous lesions and mouth cancer. Lycopene has been proven to be useful in the treatment of various precancerous lesions in the oral cavity, including oral submucous fibrosis and oral leukoplakia, and could be used in concert with other medications to prevent and treat oral cancer. Lycopene's role in preventing and treating a variety of diseases is still in its infancy, and further study and large-scale clinical trials are needed to substantiate the findings. We explored the effect of Lycopene in oral illness in this review.
Mango Ginger – Curcuma amada – The Uncommon Spice with Uncommon Pharmacotherapeutic Potentials
Authors: Choudhary Lata , Jain Ritesh , Sahu Satish
Published: April 2024

Mango ginger, or Curcuma amada Roxb., is an uncommon spice that looks like ginger but flavors like fresh mango. Pickles and other culinary items are typically made with mango ginger rhizomes. Mango ginger is widely regarded in Ayurvedic and Unani medicinal systems as a digestive aid, aphrodisiac, antipyretic, emollient, diuretic, laxative, and expectorant as well as a cure for biliousness, itching, skin disorders, bronchitis, asthma, hiccups, and inflammation caused by accidents. Aside from its numerous biological benefits, mango ginger has antioxidant, antibacterial, anti-fungal, anti-inflammatory, antiplatelet, cytotoxic, anti-allergic, hypotriglyceridemic, CNS depressing properties, analgesic, etc. Some of the major chemical constituents are volatile oils, phenolic acids, curcuminoids, starch, terpenoids, etc. The primary active components of C. amada are highlighted in this review article along with their biological roles, which may be important from a pharmacological standpoint.
Police training in responding to family, domestic and sexual violence
Authors: Dowling Christopher
Published: April 2024

Police in Australia are seeing increased reporting of family, domestic and sexual violence, while facing greater pressure to secure positive outcomes for victims. Improvements in the training police receive in responding to this violence have been identified as critical to broader efforts to reduce it. This study reviews published Australian and international research on police training in responding to family, domestic and sexual violence. The last few decades have seen a significantly expanded focus on family, domestic and sexual violence as part of police training. This, along with several notable training innovations, have underpinned a shift in police training needs from more basic concerns around correct procedure and knowledge of the law, to more advanced concerns including recognising and investigating coercive control and identifying primary aggressors. Overall, police are receptive and responsive to training, but certain types of training, particularly those with strong practical and problem-solving components, hold more promise.
COMPARATIVE STUDY ON THE APPLICABILITY OF NON-METALLIC NANOFIBERS AND REED FIBERS IN CONCRETE
Authors: WANG X. , YU H. , SADOVSKAYA E. , KOVSHAR S. , LEONOVICH S.
Published: April 2024

This article mainly conducts mechanical and mechanical experiments on non-metallic nanofiber concrete and non-metallic reed fiber concrete. Through relevant mechanical experimental data, the mechanical properties of the two fibers are compared in detail and the structures of the two fibers in concrete are determined. Durability, environmental protection, chemical stability and physical and mechanical properties hope to provide reference for the development of non-metallic fiber concrete materials.
STATIC CALCULATIONS OF A BEAM SLAB IN THE ELASTIC DIRECTION TAKING INTO ACCOUNT SHEAR STRESSES
Authors: KOZUNOVA O. , PUSENKOV A.
Published: April 2024

In the article on static calculation, it is possible to determine the crisis-strain state (CSS) of the elastic foundation under a beam slab without taking into account tangential stresses (longitudinal deformations) in an open contact, and also leads to a new calculation method taking them into account. Numerical testing is carried out using the variation-difference method (VDM) and the results are checked to estimate the shear stresses on the stress-strain state of the elastic foundation.
Working from home: An attempt to enhance employees’ work attitudes through the benefits of teleworking
Authors: Chun-Yu Lin Chun-Yu Lin , Chun-Yu Lin Piyaporn Sukdanon , Piyaporn Sukdanon Chung-Kai Huang
Published: April 2024

In this study, we investigate whether teleworking can increase employees’ job satisfaction and organizational commitment, and decrease employees’ turnover intention. We collected survey- based data in Thailand, where widespread teleworking arrangements had been implemented during the COVID-19 pandemic. The results of our analysis confirm that (1) teleworking was positively associated with job satisfaction, (2) job satisfaction was positively associated with organizational commitment and negatively associated with turnover intention, and (3) job autonomy, job burnout, and work-to-family conflict played mediating roles in the relationship between teleworking and job satisfaction. Our findings can help public-sector policymakers and private-sector managers to implement rigorous teleworking arrangements in Thailand.

 
Empatia, empatia: la cura è anche con le parole
Authors: Giuseppin Isabella
Published: April 2024

Through the narration of the case of a girl with ocular-cutaneous type 1 albinism, the author gives an example of the importance of words and the empathy they can express in managing the most challenging professional situations.
Febbre e citopenia nel neonato: pensa anche all'HLH (e dosa la ferritina!)
Authors: Operti Matteo
Published: April 2024

The author describes the case of a newborn with fever and cytopenia, eventually diagnosed as familial hemophagocytic lymphohistiocytosis.
Actor Resistance Influences Effectiveness of Ostrom’s Design Principles for Governing Contested Landscapes
Authors: Chawla Sivee , Morrison Tiffany H. , Cumming Graeme S.
Published: April 2024

Ostrom’s principles for the effective management of common pool resources emphasize the importance of local participation by affected actors in the design of rules. Principle 3 proposes that including local knowledge will facilitate the creation of effective rules that fit local social and ecological settings. However, the validity of the design principles is challenged in situations of high actor heterogeneity. We used a dynamic, spatially explicit simulation model to test Principle 3 in a simulated peri-urban area of a fast-growing city. In the model, urban actors appropriate land in a peri-urban social-ecological system. Urban appropriation fragments peri-urban ecosystems while reducing land availability for rural activities such as agriculture. We simulated the consequences of individual rural and urban actor decisions on emerging patterns of land-use types, using game theory to quantify competition for land, and metrics of landscape composition and configuration to quantify the impacts of rural resistance on landscape patterns. Landscape metrics relevant to ecosystem service provision (urban patch area, number of urban patches, clumping of urban patches and edge density of urban patches) had a non-linear response to resistance to urbanisation. Our results suggest that a small percentage of resisting rural actors can influence emerging landscape patterns; resistance as low as 10% of the rural population to urbanisation was sufficient to influence the degree of clumping of urban areas. The non-linear and varying response of emerging landscape patterns to conflict among actors, and the presence of tipping points for ecological processes that depend on connectivity or area, can create significant opportunities and challenges for the sustainable governance of land-use change in a spatially dynamic SES. We conclude that efforts to use Ostrom’s design principles to manage complex and dynamic landscapes such as peri-urban SESs must account for actor heterogeneity and the potential influence of actor resistance on landscape patterns.
CoDesign for Discovery in Social Sciences and Humanities
Authors: De Paoli Stefano , Forbes Paula , Andreini Giulio , Maryl Maciej , Błaszczyńska Marta
Published: April 2024

GoTriple is a novel discovery platform for Social Sciences and Humanities (SSH) in Europe. Discovery is a phase of research where scholars seek to locate resources for their work, such as publications or previous projects. The paper details the work done for involving the SSH community in the codesign of GoTriple, focusing on the research discovery activities. It is an investigation of the user needs and barriers toward digital discovery for the SSH community, conducted through codesign. This work encompassed interviews, a questionnaire, codesign workshops and evaluation activities. The paper reports on some outcomes for the codesign and how user needs were identified and served by novel designs supporting discovery for SSH. This process of design is both concerned with creating digital tools for discovery and with the creation of a community of users that could make the platform thrive. The main contribution of the work is therefore the identification of the user needs for digital discovery in SSH and a series of insights on the design with the user community. The paper comprises a report on how codesign principles do support such work.
Primary omental ectopic pregnancy after frozen-thawed single embryo transfer: A case report and review of the literature
Authors: Koniares Katherine , Godiwala Prachi , Benadiva Claudio , DiLuigi Andrea
Published: April 2024

Introduction: The objective of this case report is to present the first known case of a primary omental ectopic pregnancy following frozen-thawed embryo transfer.

Case Report: A 35-year-old G0 female with severe male factor infertility underwent a frozen-thawed single embryo transfer. Serial transvaginal ultrasounds and beta human chorionic gonadotropin levels led to the diagnosis of ectopic pregnancy. The patient did not respond to medical management with methotrexate. On laparoscopy, an ectopic pregnancy was diagnosed on the greater omentum. The pregnancy was resected with the LigaSure device. Pathology evaluation was consistent with an omental ectopic pregnancy.

Conclusion: Although rare, omental ectopic pregnancy should remain in the differential in the setting of a pregnancy of unknown location.
SOIL BACTERIAL ISOLATE SHOWING A POTENTIAL OF MANCOZEB DEGRADATION AND PLANT GROWTH ENHANCEMENT
Authors: Gajjar Priyanka , Kiri Bhavya , Shah Hiral
Published: April 2024

Mancozeb, a dithiocarbamates pesticide, has been widely used for weed control. Despite mancozeb’s endurance and toxicity towards biological forms, its removal or degradation from contaminated area has become a concern, leading to bioremediation processes. From agricultural fields contaminated with pesticides, two bacterial strains, Pseudomonas aeruginosa (PM3) and Rhizobium pusense (PM10) were identified that have the ability to degrade mancozeb. Within a 10-day timeframe, these isolates were able to break down between 97.49% and 98.99% of the mancozeb’s original concentration (100mg/L). In both sterilised and non-sterilised soils, these strains showed the ability to degrade mancozeb by 95-100% of their initial concentration (200mg/kg). These strains also exhibited notable characteristics that supported plant development, including the ability to solubilize phosphate, produce both indole acetic acid and ammonia in absence and presence of mancozeb. Mancozeb has shown detrimental influence on plant through plant growth experiments and cause a drop-in growth indicators, such as percentage germination, plant biomass and plant height. Inoculation of bacterial isolates with mancozeb was shown to considerably improve plant growth in terms of plant weight and plant length. This study revealed that mancozeb degrading strains have the potential to become a strong contender for increasing agricultural productivity in pesticide contaminated soils.
ՀՐԴԵՀԱՏԵԽՆԻԿԱԿԱՆ ՓՈՐՁԱՔՆՆՈՒԹՅԱՆ ՄԵՋ ՆԱՎԹԱՄԹԵՐՔՆԵՐԻ ԵՎ ԴՅՈՒՐԱՎԱՌ ՀԵՂՈՒԿՆԵՐԻ ՀԵՏՔԵՐԻ ՀԱՅՏՆԱԲԵՐՄԱՆ ԵՎ ՆՈՒՅՆԱԿԱՆԱՑՄԱՆ ԽՆԴՐԱՀԱՐՈՒՅՑ ՀԱՐՑԵՐ
Authors: Gahramanyan J.G.
Published: April 2024

Քրեական վարույթի շրջանակներում հրդեհի վայրի զննության ժամանակ նավթամթերքների և դյուրավառ հեղուկների կամ դրանց հետքերի հայտնաբերումը, հետագա լաբորատոր հետազոտությունների նպատակով, կարևորագույն պայման է, որը թույլ է տալիս որոշել հրդեհի օջախը և առաջ քաշել հրդեհի տեխնիկական պատճառների վարկածը՝ հանցագործության կատարման մեխանիզմի հետագա բացահայտմամբ: Հոդվածում ընդգծվում և նկարագրվում են հրդեհի վայրում նավթամթերքների և դյուրավառ հեղուկների հայտնաբերման բնութագրական առանձնահատկությունները: Միևնույն ժամանակ, նշվում է, որ հաշվի առնելով ընդհանրացված փորձագիտական գործնական փորձը, հաճախ նյութական օբյեկտների (ապացույցների) նմուշառումը բարդանում է սկզբնական նյութի քիչ քանակության առկայությամբ' բաց կրակի և ուժեղ ջերմային ազդեցության պայմաններում դրանց գոլորշիացման և այրման պատճառով, ինչը, իր հերթին նվազեցնում է դրանց հայտնաբերման արդյունավետությունը: Սույն հոդվածում ներկայացվում է հրդեհի վայրի զննման ընթացքում նավթամթերքների և դյուրավառ հեղուկների հայտնաբերման համար հետազոտական մեթոդների համեմատական վերլուծություն՝ այդ թվում գործիքային, որոնց հիման վրա բացահայտվում են դեպքի վայրի իրադրության ֆիքսացիային բնորոշ նշաններ և մշակվում են ինչպես հրդեհի վայրից նմուշառման հիմնական սկզբունքները, այնպես էլ դրանց պահպանման համապատասխան պայմանների ապահովումը:
Բանալի բառեր. հրդեհատեխնիկական փորձաքննություն, հրդեհի վայրի զննում, նմուշառում, նավթամթերք, դյուրավառ հեղուկներ:
Bullying: psychopedagogical advisory actions for its treatment in the school context
Authors: Hawthorn-Preval Marisnelsi , Favier Meglis River
Published: April 2024

The research addresses the topic of bullying in the school context. The objective is to develop psycho-pedagogical advisory actions that enhance the preparation of teachers for the treatment of school bullying, in third-grade students at the Elena Fuentes López school. Research methods such as theoretical, empirical and mathematical methods were used in the study. The diagnosis of the current state showed insufficient treatment of bullying. The assessment of the proposed actions revealed their feasibility through methodological triangulation with the application of the systematization of the pedagogical experience and the interview with teachers.
Development and Evaluation of a Computer Vision System for Robot Navigation and Object Recognition in Real-World Environments
Authors: Helgo Malene
Published: April 2024

The article discusses the vision framework for computing that includes image recognition, classification, prioritization, and navigation control modules. In this framework, a user model is used to feed the robotic controllers, whose performance improves in dynamic virtual contexts. In contrast, the vision module uses a multi-level perceptual neural network capable of efficient image segmentation, object recognition, and color segmentation, using the control module Position-Based Vision Serving (PBVS) and actions such as Avoid Collision (), Go-Ahead (), and Follow( ). It controls the motion of the robot, so the system successfully tested and met the requirements of the Antimedia Robotics Pioneer I robot. In addition, it was consistent with real life. The results show the effectiveness of the system in providing effective guidance and avoiding obstacles. Furthermore, the study investigates the use of artificial neural networks for image recognition and classification. In addition, it requires the use of SpCoMapping to add language maps to useful information. In summary, studies have emphasized the potential of computer vision and neural networks to improve robotic communication and language learning.
El proyecto filosófico de Gianni Vattimo: lectura hermenéutica Heidegger-Nietzsche
Authors: Sánchez Milagros
Published: April 2024

En el artículo que sigue se muestra el hilo conductor de reflexión que sostiene el proyecto de G. Vattimo. El acusado estudio de Friedrich Nietzsche, Martin Heidegger y Hans-Georg Gadamer funda la base para su pensamiento “posmetafísico”. De Nietzsche toma el diagnostico de una cultura nihilista. Y de Heidegger hereda la concepción “epocal” del ser, es decir, la postura según la cual el ser no es, sino que acontece.
Analysis between Demographic Factors, Chronic Conditions and Its Association with Increased Hearing Threshold On Factory Workers Exposed to Noise: A Cross Sectional Study in 2022
Authors: Roscoe Roscoe , Purwito Adi Nuri , Kekalih Aria
Published: April 2024

Background: Exposure to noise in workplace is the leading cause of increased hearing threshold and hearing loss among factory workers. There are other factors other than noise than can cause increased hearing threshold such as age, length of work, history of hypertension, diabetes, dyslipidemia, Body Mass Index and smoking habit. PT K is a company that produce heavy machinery parts for construction where workers are exposed to noise above Threshold Limit Value (TLV).Methods: A cross-sectional research of 965 employees was conducted after passing the ethical evaluation based on the 2022 medical check-up results. Samples were taken from total secondary data from the company’s medical records and data verification was done to eliminate duplication and confirm data validity. Univariate, chi-square for bivariate analyses were performed.Result: The prevalence of increased hearing threshold among workers is 39.6%. The factors that associated with the prevalence of increased hearing threshold were determined to be older age group (p<0.001), history hypertension (p=0.003), dyslipidemia (p=0.008) and overweight – obese Body Mass Index (p=0.002).Conclusion: Older age group, length of work, works departments, history of high blood pressure, dyslipidemia and overweight – obese Body Mass Index were significant risk factors associated with increased hearing threshold. The risk of increased hearing threshold is 3.2 times higher in workers above 36 years old. This indicate the importance of preparing better mitigation strategy of noise control and hearing conservation program, particularly in workers older than 36 years old.