bluuebunny/crossref_metadata_2025 huggingface dataset:
Exposure of Human Gastric Cells to Oxidized Lipids Stimulates Pathways of Amino Acid Biosynthesis on a Genomic and Metabolomic Level
Authors: Zaunschirm Mathias , Pignitter Marc , Kopic Antonio , Keßler Claudia , Hochkogler Christina , Kretschy Nicole , Somoza Mark Manuel , Somoza Veronika
Published: November 2019

The Western diet is characterized by a high consumption of heat-treated fats and oils. During deep-frying processes, vegetable oils are subjected to high temperatures which result in the formation of lipid peroxidation products. Dietary intake of oxidized vegetable oils has been associated with various biological effects, whereas knowledge about the effects of structurally-characterized lipid peroxidation products and their possible absorption into the body is scarce. This study investigates the impact of linoleic acid, one of the most abundant polyunsaturated fatty acids in vegetable oils, and its primary and secondary peroxidation products, 13-HpODE and hexanal, on genomic and metabolomic pathways in human gastric cells (HGT-1) in culture. The genomic and metabolomic approach was preceded by an up-to-six-hour exposure study applying 100 µM of each test compound to the apical compartment in order to quantitate the compounds’ recovery at the basolateral side. Exposure of HGT-1 cells to either 100 µM linoleic acid or 100 µM 13-HpODE resulted in the formation of approximately 1 µM of the corresponding hydroxy fatty acid, 13-HODE, in the basolateral compartment, whereas a mean concentration of 0.20 ± 0.13 µM hexanal was quantitated after an equivalent application of 100 µM hexanal. An integrated genomic and metabolomic pathway analysis revealed an impact of the linoleic acid peroxidation products, 13-HpODE and hexanal, primarily on pathways related to amino acid biosynthesis (p < 0.05), indicating that peroxidation of linoleic acid plays an important role in the regulation of intracellular amino acid biosynthesis.
Reflectometry Reveals Accumulation of Surfactant Impurities at Bare Oil/Water Interfaces
Authors: Scoppola Ernesto , Micciulla Samantha , Kuhrts Lucas , Maestro Armando , Campbell Richard A. , Konovalov Oleg V. , Fragneto Giovanna , Schneck Emanuel
Published: November 2019

Bare interfaces between water and hydrophobic media like air or oil are of fundamental scientific interest and of great relevance for numerous applications. A number of observations involving water/hydrophobic interfaces have, however, eluded a consensus mechanistic interpretation so far. Recent theoretical studies ascribe these phenomena to an interfacial accumulation of charged surfactant impurities in water. In the present work, we show that identifying surfactant accumulation with X-ray reflectometry (XRR) or neutron reflectometry (NR) is challenging under conventional contrast configurations because interfacial surfactant layers are then hardly visible. On the other hand, both XRR and NR become more sensitive to surfactant accumulation when a suitable scattering length contrast is generated by using fluorinated oil. With this approach, significant interfacial accumulation of surfactant impurities at the bare oil/water interface is observed in experiments involving standard cleaning procedures. These results suggest that surfactant impurities may be a limiting factor for the investigation of fundamental phenomena involving water/hydrophobic interfaces.
Microbial Conversion of Toxic Resin Acids
Authors: Luchnikova Natalia A. , Ivanova Kseniya M. , Tarasova Ekaterina V. , Grishko Victoria V. , Ivshina Irina B.
Published: November 2019

Organic wood extractives—resin acids—significantly contribute to an increase in the toxicity level of pulp and paper industry effluents. Entering open ecosystems, resin acids accumulate and have toxic effects on living organisms, which can lead to the ecological imbalance. Among the most effective methods applied to neutralize these ecotoxicants is enzymatic detoxification using microorganisms. A fundamental interest in the in-depth study of the oxidation mechanisms of resin acids and the search for their key biodegraders is increasing every year. Compounds from this group receive attention because of the need to develop highly effective procedures of resin acid removal from pulp and paper effluents and also the possibility to obtain their derivatives with pronounced pharmacological effects. Over the past fifteen years, this is the first report analyzing the data on distribution, the impacts on living organisms, and the microbial transformation of resin acids. Using the example of dehydroabietic acid—the dominant compound of resin acids in effluents—the review discusses the features of interactions between microorganisms and this pollutant and also highlights the pathways and main products of resin acid bioconversion.
Mumefural Ameliorates Cognitive Impairment in Chronic Cerebral Hypoperfusion via Regulating the Septohippocampal Cholinergic System and Neuroinflammation
Authors: Bang Jihye , Kim Min-Soo , Jeon Won Kyung
Published: November 2019

Chronic cerebral hypoperfusion (CCH) causes cognitive impairment and neurogenic inflammation by reducing blood flow. We previously showed that Fructus mume (F. mume) improves cognitive impairment and inhibits neuroinflammation in a CCH rat model. One of the components of F. mume, Mumefural (MF), is known to improve blood flow and inhibit platelet aggregation. Whether MF affects cerebral and cognitive function remains unclear. We investigated the effects of MF on cognitive impairment and neurological function-related protein expression in the rat CCH model, established by bilateral common carotid arterial occlusion (BCCAo). Three weeks after BCCAo, MF (20, 40, or 80 mg/kg) was orally administrated once a day for 42 days. Using Morris water maze assessment, MF treatment significantly improved cognitive impairment. MF treatment also inhibited cholinergic system dysfunction, attenuated choline acetyltransferase-positive cholinergic neuron loss, and regulated cholinergic system-related protein expressions in the basal forebrain and hippocampus. MF also inhibited myelin basic protein degradation and increased the hippocampal expression of synaptic markers and cognition-related proteins. Moreover, MF reduced neuroinflammation, inhibited gliosis, and attenuated the activation of P2X7 receptor, TLR4/MyD88, NLRP3, and NF-κB. This study indicates that MF ameliorates cognitive impairment in BCCAo rats by enhancing neurological function and inhibiting neuroinflammation.
Geriatric Nutritional Risk Index Is Associated with Unique Health Conditions and Clinical Outcomes in Chronic Kidney Disease Patients
Authors: Lin Ting-Yun , Hung Szu-Chun
Published: November 2019

Malnutrition is prevalent in patients with chronic kidney disease (CKD). However, current nutrition screening tools are not specific to the CKD population. In the present study, we aimed to investigate whether the geriatric nutritional risk index (GNRI), a simple tool designed for assessing nutrition-related risks in the elderly population, is associated with unique aspects of CKD such as fluid status, residual renal function, proteinuria, and inflammation, and whether it predicts clinical outcomes. The GNRI was calculated by incorporating serum albumin and anthropometric measurements in 326 patients with nondialysis stage 3–5 CKD who were followed up from September 2011 to March 2017 for end-stage renal disease (ESRD) and the composite outcome of all-cause death and cardiovascular events. Patients were stratified into tertiles according to baseline GNRI levels. Patients in the lowest GNRI tertile were more likely to have significantly higher levels of overhydration, proteinuria, and serum inflammatory markers and tended to have lower lean body mass and estimated glomerular filtration rate when compared with patients in the middle and upper GNRI tertiles. In multivariate linear regression analyses, the GNRI was independently associated with overhydration, proteinuria, and interleukin-6. During a median follow-up of 4.9 years, 101 patients developed ESRD; 40 deaths, and 68 cardiovascular events occurred. Patients in the lowest GNRI tertile had significantly increased risks of ESRD (hazard ratio (HR): 3.15, 95% confidence interval (CI): 1.95–5.07, p < 0.001) and the composite outcome (HR: 1.79, 95% CI: 1.10–2.92, p = 0.019) in fully adjusted models (reference: middle and upper GNRI tertiles). The GNRI takes CKD-specific health conditions into account. In addition, CKD patients with lower GNRI scores had a significantly higher risk of adverse clinical outcomes. Our findings suggest that the GNRI is an appropriate tool for nutrition screening and a prognostic predictor among patients with nondialysis stage 3–5 CKD.
An In Situ Gelling System for the Local Treatment of Inflammatory Bowel Disease (IBD). The Loading of Maqui (Aristotelia chilensis) Berry Extract as an Antioxidant and Anti-Inflammatory Agent
Authors: Tenci Marika , Rossi Silvia , Giannino Valentina , Vigani Barbara , Sandri Giuseppina , Bonferoni Maria Cristina , Daglia Maria , Longo Luigi Maria , Macelloni Cristina , Ferrari Franca
Published: November 2019

The aim of the present work was the development of an innovative in situ gelling system, to be applied on the mucosa of the distal colon via rectal route. The system consisted of three polymers having different functions: gellan (GG), able to jellify in presence of ions; methylcellulose (MC), a thermosensitive polymer with a gelation temperature close to 50 °C; and hydroxypropylcellulose (HPC), a mucoadhesive polymer. The three polymers were able to act synergistically, increasing the permanence of the vehicle on the mucosa and forming a protective gel layer. A DoE approach, “simplex centroid mixture design,” was used to identify the optimal quantitative composition of the vehicle. The response variables considered were: vehicle viscosity at room temperature; increase in vehicle viscosity on increasing temperature (from room to physiological value) and upon dilution with simulated colonic fluid (SCF); and viscoelastic behavior, thixotropic area, and mucoadhesion properties of the gel formed at 37 °C upon dilution in SCF. The optimized vehicle was loaded with maqui berry extract (MBE), known for its antioxidant and anti-inflammatory properties. MBE loading (0.5% w/w) into the vehicle improved rheological and mucoadhesive properties of the formulation. Both MBE and the optimized vehicle were not cytotoxic towards human fibroblasts and Caco-2 cells. Moreover, the optimized vehicle did not affect MBE antioxidant properties.
Developing Land Surface Directional Reflectance and Albedo Products from Geostationary GOES-R and Himawari Data: Theoretical Basis, Operational Implementation, and Validation
Authors: He Tao , Zhang Yi , Liang Shunlin , Yu Yunyue , Wang Dongdong
Published: November 2019

The new generation of geostationary satellite sensors is producing an unprecedented amount of Earth observations with high temporal, spatial and spectral resolutions, which enable us to detect and assess abrupt surface changes. In this study, we developed the land surface directional reflectance and albedo products from Geostationary Operational Environment Satellite-R (GOES-R) Advanced Baseline Imager (ABI) data using a method that was prototyped with the Moderate Resolution Imaging Spectroradiometer (MODIS) data in a previous study, and was also tested with data from the Advanced Himawari Imager (AHI) onboard Himawari-8. Surface reflectance is usually retrieved through atmospheric correction that requires the input of aerosol optical depth (AOD). We first estimated AOD and the surface bidirectional reflectance factor (BRF) model parameters simultaneously based on an atmospheric radiative transfer formulation with surface anisotropy, and then calculated the “blue-sky” surface broadband albedo and directional reflectance. This algorithm was implemented operationally by the National Oceanic and Atmospheric Administration (NOAA) to generate the GOES-R land surface albedo product suite with a daily updated clear-sky satellite observation database. The “operational” land surface albedo estimation from ABI and AHI data was validated against ground measurements at the SURFRAD sites and OzFlux sites and compared with the existing satellite products, including MODIS, Visible infrared Imaging Radiometer (VIIRS), and Global Land Surface Satellites (GLASS) albedo products, where good agreement was found with bias values of −0.001 (ABI) and 0.020 (AHI) and root-mean-square-errors (RMSEs) less than 0.065 for the hourly albedo estimation. Directional surface reflectance estimation, evaluated at more than 74 sites from the Aerosol Robotic Network (AERONET), was proven to be reliable as well, with an overall bias very close to zero and RMSEs within 0.042 (ABI) and 0.039 (AHI). Results show that the albedo and reflectance estimation can satisfy the NOAA accuracy requirements for operational climate and meteorological applications.
Reconstruction of Three-Dimensional Dynamic Wind-Turbine Wake Wind Fields with Volumetric Long-Range Wind Doppler LiDAR Measurements
Authors: Beck Hauke , Kühn Martin
Published: November 2019

This paper presents a method for reconstructing the wake wind field of a wind turbine based on planar light detection and ranging (LiDAR) scans crossing the wake transversally in the vertical and horizontal directions. Volumetric measurements enable the study of wake characteristics in these two directions. Due to a lack of highly resolved wind speed measurements as reference data, we evaluate the reconstruction in a synthetic environment and determine the reconstruction errors. The wake flow of a multi-megawatt wind turbine is calculated within a 10-min large-eddy simulation (LES) for high-thrust loading conditions. We apply a numerical LiDAR simulator to this wake wind field to achieve realistic one-dimensional velocity data. We perform a nacelle-based set-up with combined plan position indicator and range height indicator scans with eight scanning velocities each. We temporally up-sample the synthetic LiDAR data with a weighted combination of forward- and backward-oriented space–time conversion to retrospectively extract high-resolution wake characteristic dynamics. These dynamics are used to create a dynamic volumetric wake deficit. Finally, we reconstruct the dynamic wake wind field in three spatial dimensions by superposing an ambient wind field with the dynamic volumetric wake deficit. These results demonstrate the feasibility of wake field reconstruction using long-range LiDAR measurements.
A Comparative Study on Drivers for Corporate Environmental Responsibility, EU15 vs. EU-NMS13
Authors: Hatmanu Mariana , Sandu Christiana Brigitte , Jaba Elisabeta
Published: November 2019

The activity of enterprises has a major impact on the quality of the environment. Deterioration and abusive exploitation of resources, with no concern for environmental protection, bring the need for a higher level of corporate environmental responsibility (CER). Consequently, CER has become a sine qua non concern of small and medium enterprises (SMEs). This study aims to estimate the importance of drivers for CER. It was conducted on a sample of SMEs from two groups of EU countries characterised by a different level of social and economic development backgrounds. The authors applied statistical analysis to estimate the importance of the effect of drivers for CER using the logit model and the nomogram. The logit model shows that the most important effects of drivers for CER correspond to the company’s core values, the impact of resource efficiency actions on the production costs, and the return on the investments made on resource efficiency. The magnitude of these effects is different for the SMEs from the two EU groups. Also, the study underlines the significant effect of SMEs’ size for CER. The differences for the two groups of countries call for policies stimulating environmental responsibility, differentiated by the two types of SMEs.
Light Pollution, Circadian Photoreception, and Melatonin in Vertebrates
Authors: Grubisic Maja , Haim Abraham , Bhusal Pramod , Dominoni Davide M. , Gabriel Katharina M. A. , Jechow Andreas , Kupprat Franziska , Lerner Amit , Marchant Paul , Riley William , Stebelova Katarina , van Grunsven Roy H. A. , Zeman Michal , Zubidat Abed E. , Hölker Franz
Published: November 2019

Artificial light at night (ALAN) is increasing exponentially worldwide, accelerated by the transition to new efficient lighting technologies. However, ALAN and resulting light pollution can cause unintended physiological consequences. In vertebrates, production of melatonin—the “hormone of darkness” and a key player in circadian regulation—can be suppressed by ALAN. In this paper, we provide an overview of research on melatonin and ALAN in vertebrates. We discuss how ALAN disrupts natural photic environments, its effect on melatonin and circadian rhythms, and different photoreceptor systems across vertebrate taxa. We then present the results of a systematic review in which we identified studies on melatonin under typical light-polluted conditions in fishes, amphibians, reptiles, birds, and mammals, including humans. Melatonin is suppressed by extremely low light intensities in many vertebrates, ranging from 0.01–0.03 lx for fishes and rodents to 6 lx for sensitive humans. Even lower, wavelength-dependent intensities are implied by some studies and require rigorous testing in ecological contexts. In many studies, melatonin suppression occurs at the minimum light levels tested, and, in better-studied groups, melatonin suppression is reported to occur at lower light levels. We identify major research gaps and conclude that, for most groups, crucial information is lacking. No studies were identified for amphibians and reptiles and long-term impacts of low-level ALAN exposure are unknown. Given the high sensitivity of vertebrate melatonin production to ALAN and the paucity of available information, it is crucial to research impacts of ALAN further in order to inform effective mitigation strategies for human health and the wellbeing and fitness of vertebrates in natural ecosystems.
Regional Ethnocentrism on the Food Market as a Pattern of Sustainable Consumption
Authors: Bryła Paweł
Published: November 2019

The paper aims to assess the level and predictors of regional ethnocentrism on the market of regional food products in the context of sustainable consumption. The study contributes to the theory of consumer ethnocentrism by extending our knowledge about its regional dimension. Regional ethnocentrism is the preference for products originating from the consumer’s region. I conducted a survey in a representative sample of 1000 inhabitants of Poland with the use of the CAWI (Computer-Assisted Web Interview) methodology. Regional ethnocentric consumers were characterized by a significantly more favorable attitude to regional food products compared to the rest of the sample. In a multiple regression model, the following eight statistically significant predictors of the regional ethnocentrism were identified: the importance of brand and retailer trust on the food market; the importance of quality signs in regional food purchases; opinion that insufficient marketing constitutes an important barrier to the development of the regional food market; buying regional products in shops owned by producers, rather than large distribution networks; frequency of purchasing regional products as a tourist; and national ethnocentrism on the regional food market. These predictors are strongly related to the three major pillars of sustainable development—economic, social, and ecological.
Use of FTIR Spectroscopy and Chemometrics with Respect to Storage Conditions of Moldavian Dragonhead Oil
Authors: Matwijczuk Arkadiusz , Oniszczuk Tomasz , Matwijczuk Alicja , Chruściel Edyta , Kocira Anna , Niemczynowicz Agnieszka , Wójtowicz Agnieszka , Combrzyński Maciej , Wiącek Dariusz
Published: November 2019

Oils often have similar properties and can be difficult to identify based on color, smell or taste alone. The present paper suggests the use of Fourier-transform infrared spectroscopy (FTIR) in combination with chemometric methods to explore similarities and differentiate between samples of Moldavian dragonhead oil subjected to different storage conditions. Dragonhead is a plant characterized by very good honey output and ease of cultivation. Principal component analysis (PCA) was applied to a standard, full range of FTIR spectra. Additionally, hierarchical cluster analysis (HCA) was employed to explore the organization of the samples in groups relative to their “proximity” (similarity), by way of Euclidean distance measurement. PC1 and PC2 accounted respectively for 85.4% and 10.1% of the total data variance. PC1 and PC2 were strongly, negatively correlated within the entire spectral range; the only exception was the region corresponding to νs(-C-Hvst, -CH2) vibrations (aliphatic groups in triglycerides), where PC2 was positively correlated. The use of FTIR spectral analysis revealed noticeable differences in the intensity of bands characteristic of the ageing processes (markers of oxidative processes, etc.) taking place in oleaginous samples and related to the processes of fatty acids oxidation.
Ideals of Numerical Semigroups and
Error-Correcting Codes
Authors: Bras-Amorós Maria
Published: November 2019

Several results relating additive ideals of numerical semigroups and algebraic-geometrycodes are presented. In particular, we deal with the set of non-redundant parity-checks, the codelength, the generalized Hamming weights, and the isometry-dual sequences of algebraic-geometrycodes from the perspective of the related Weierstrass semigroups. These results are related tocryptographic problems such as the wire-tap channel, t-resilient functions, list-decoding, networkcoding, and ramp secret sharing schemes.
The Diversity of Venom: The Importance of Behavior and Venom System Morphology in Understanding Its Ecology and Evolution
Authors: Schendel Vanessa , Rash Lachlan D. , Jenner Ronald A. , Undheim Eivind A. B.
Published: November 2019

Venoms are one of the most convergent of animal traits known, and encompass a much greater taxonomic and functional diversity than is commonly appreciated. This knowledge gap limits the potential of venom as a model trait in evolutionary biology. Here, we summarize the taxonomic and functional diversity of animal venoms and relate this to what is known about venom system morphology, venom modulation, and venom pharmacology, with the aim of drawing attention to the importance of these largely neglected aspects of venom research. We find that animals have evolved venoms at least 101 independent times and that venoms play at least 11 distinct ecological roles in addition to predation, defense, and feeding. Comparisons of different venom systems suggest that morphology strongly influences how venoms achieve these functions, and hence is an important consideration for understanding the molecular evolution of venoms and their toxins. Our findings also highlight the need for more holistic studies of venom systems and the toxins they contain. Greater knowledge of behavior, morphology, and ecologically relevant toxin pharmacology will improve our understanding of the evolution of venoms and their toxins, and likely facilitate exploration of their potential as sources of molecular tools and therapeutic and agrochemical lead compounds.
Climate Change Impact Assessment on Freshwater Inflow into the Small Aral Sea
Authors: Ayzel Georgy , Izhitskiy Alexander
Published: November 2019

During the last few decades, the rapid separation of the Small Aral Sea from the isolated basin has changed its hydrological and ecological conditions tremendously. In the present study, we developed and validated the hybrid model for the Syr Darya River basin based on a combination of state-of-the-art hydrological and machine learning models. Climate change impact on freshwater inflow into the Small Aral Sea for the projection period 2007–2099 has been quantified based on the developed hybrid model and bias corrected and downscaled meteorological projections simulated by four General Circulation Models (GCM) for each of three Representative Concentration Pathway scenarios (RCP). The developed hybrid model reliably simulates freshwater inflow for the historical period with a Nash–Sutcliffe efficiency of 0.72 and a Kling–Gupta efficiency of 0.77. Results of the climate change impact assessment showed that the freshwater inflow projections produced by different GCMs are misleading by providing contradictory results for the projection period. However, we identified that the relative runoff changes are expected to be more pronounced in the case of more aggressive RCP scenarios. The simulated projections of freshwater inflow provide a basis for further assessment of climate change impacts on hydrological and ecological conditions of the Small Aral Sea in the 21st Century.
A Novel, Coupled CFD-DEM Model for the Flow Characteristics of Particles Inside a Pipe
Authors: Zhou Haotong , Wang Guihe , Jia Cangqin , Li Cheng
Published: November 2019

This study developed a novel, 3D coupled computational fluid dynamics (CFD)-discrete element method (DEM) model by coupling two software programs, OpenFOAM and PFC3D, to solve problems related to fluid–particle interaction systems. The complete governing equations and the flow chart of the coupling calculations are clearly presented herein. The coupled CFD-DEM model was first benchmarked using two classic geo-mechanics problems, for which the analytical solutions are available. Then, the CFD-DEM model was employed to investigate the flow characteristics of a particle heap subjected to the effects of water inside a pipe under different conditions. The results showed that particle size and pipe inclination angle can significantly affect the particle flow morphology, total kinetic energy and erosion rate for mono-sized particles, whereas polydisperse particles had a slight effect. This model can accurately describe the flow characteristics of particles inside a pipe, and the results of this study were consistent with those of previous studies. The reliability of this model was further demonstrated, which showed that this model can provide valuable references for solving similar problems such as soil erosion and bridge scour problems.
IDENTIFIKASI JAMUR PENYEBAB TINEA PEDIS PADA KAKI PENYADAP KARET DI PTPN VIII CIKUPA DESA CIKUPA KECAMATAN BANJARSARI KABUPATEN CIAMIS TAHUN 2017
Authors: Farihatun Atun
Published: November 2019

Tinea pedis atau yang lebih dikenal dengan kutu air adalah penyakit akibat infeksi jamur dermatofita yang mengenai kulit pada jari-jari kaki, telapak kaki, dan bagian lateral kaki.Penyebab penyakit ini adalah seluruh genus dermatofita terutama Trichophyton rubrum, dan Trichophyton mentagrophytes.Namun penyebab tersering yaitu, Trichophyton rubrum, Trichophyton mentagrophytes, dan Trichophyton epidermophyton floccosum.Penyakit ini merupakan penyakit infeksi dermatofita yang sering terjadi (FKUI, 2008).Kelainan mengenai kulit diantara jari-jari kaki, terutama antara jari ke 3-4 dan ke 4-5, telapak kaki dan bagian lateral kaki.Faktor predisposisi berupa kaki yang selalu basah, baik oleh air (tukang cuci), maupun oleh keringat (sepatu tertutup dan memakai kaos kaki) dengan waktu yang lama.(FKUI, 2008).
Gambaran Fraksi Hemoglobin Penderita Talasemia Menggunakan Metode Elektroforesis Kapiler
Authors: Kesuma Suryanata , Octavia Elita
Published: November 2019

Thalassemia is a hereditary blood disease that is found in Indonesia. One method of examining modern thalassemia is the examination of hemoglobin fraction using the Capillary Electrophoresis. This method has a high level of accuracy and precision for quantification of hemoglobin variants.The purpose of this study was to determine the hemoglobin fraction in thalassemia patients using the Capillary Electrophoresis method. This type of research is descriptive research. The sample of this study was 3 blood specimens from thalassemia sufferers.The results showed that the first specimen, age 4 years had HbA levels of 59.9%, HbA2 levels of 4.3%, HbF levels of 14.7% and HbE levels of 21.1%. In the second specimen, 8 years of age had 88.7% HbA, 2.5% HbA2, 3.2% HbF and 5.6% HbE. In the third specimen, the age of 13 years had HbA levels of 93.8%, HbA2 levels of 4.9% and HbF levels of 1.3%.The conclusion of this study was the first specimen, HbA levels decreased, HbA2 levels increased and HbF levels increased and hemoglobin variants were found, namely HbE. In the second specimen, HbA levels decreased from the normal range, HbA2 levels were in the normal range and HbF levels increased and hemoglobin variants were found, namely HbE. In the third specimen, HbA levels decreased from the normal range, HbA2 levels and HbF levels increased, but no hemoglobin variants were found in this specimen.
GAMBARAN KADAR ENZIM KOLINESTERASE DALAM DARAH PADA KELOMPOK TANI MEKAR NADI DI DESA BATUNYA KECAMATAN BATURITI
Authors: Mastra Nyoman
Published: November 2019

Background: Pesticides is poison and dangerous materials. It can cause negative effects to human health directly or indirectly. Blood cholinesterase enzyme analysis is one of the methods to indicate that someone is poisons by pesticide. Purpose: This research is a descriptive study. The aim of this study is to illustrate the cholinesterase levels in the farmer’s blood especially the farmers in Batunya village. Methods: The population in this research was 30 farmers who are the members of Groups Tani Mekar Nadi. The sampling method that used in this research was saturation sampling. Data collection used the questionnaire. The test-mateChE cholinesterase test system (model 400) is the device that used to check the level of cholinesterase in the farmers’ blood. Result: The result show that 22 peoples (73,3%) cholinesterase level was abnormal. In the other hand, 8 of the farmer (26,7%) has normal level of cholinesterase. Conclusion: From the result it can be concluded that it’s still important to monitor the level of cholinesterase in farmers’ blood to increase awareness towards the danger of pesticide, always use self-protection device, and conducting a good pesticide management.Keywords: pesticide, cholinesterase, poisoned
Hubungan Indeks Masa Tubuh dengan Kadar Trigliserida Pada Penenun Tradisional di Tenganan Karangasem
Authors: Dhyanaputri I G.A. Sri
Published: November 2019

Background Body mass index is the one of the marker of nutritional status related to obesity. Obesity is a multifactorial disease that can lead to an increase in triglycerides. This situation is one of the causes of cardiovascular disease. Objective This study aims to determine the relationship between body mass index in the levels of trigliycerides in weavers in Tenganan Village Karangasem. Methods Designed as study correlation study. The study was done to 26 respondents that were chosen by saturated sampling method. Data of body mass index were measured by anthropometric measurements and data of triglycerides level measured by using a dialab autolyser. The Results showed that 50,00% participants got obesity and 42,31% participants had increased triglycerides level, which six participants (23,08%) got a high limit and five participants (19,23%) in the high category. Based on the product moment test, a score is significant correlation between body mass index with triglycerides (p: 0,000) (α: 0,05). It was Concluded there is a relationship between body mass index with triglycerides level of weavers at Tenganan Village Karangasem.Keywords: body mass index, obesity, triglycerides
PENGARUH PENUNDAAN PEMERIKSAAN URIN TERHADAP JUMLAH LEUKOSIT PADA PENDERITA INFEKSI SALURAN KEMIH
Authors: Sarihati I Gusti Agung Dewi , Dewanti Bunga , Burhannuddin Burhannuddin
Published: November 2019

Abstract. Urine is the rest of the body's metabolism that is released through the process of urinalization. Urine examination aims to determine the condition of the kidney and other urinary tracts. Delays in examinations in the laboratory often occur resulting in disturbed urine stability. This study aims to determine the effect of delays on the number of urine leukocytes in patients with urinary tract infections. This research with posttest only control group design using four control and treatment groups each consisting of 9 samples. The control group is the result of urine examination which is examined before 30 minutes while the treatment group is the result of urine examination after 1, 2 and 3 hours since being collected. The results showed an average difference between the control and treatment groups, especially there was a significant reduction in the 3-hour delay group.Keywords: urine leukocytes, delay in urine examination
KORELASI TINGKAT PENDIDIKAN DENGAN PARTISIPASI PEMILIH PEMULA DALAM PEMILU NASIONAL SERENTAK 2019 DI KABUPATEN INDRAGIRI HULU
Authors: Yusnedi Yusnedi , Utami Sabrina
Published: November 2019

Abstract

 

 

This research is in Indragiri Hulu Regency, which is specialized in Rengat District. The purpose of this study is to determine how the correlation between the level of education with the participation of novice voters in the 2019 Election in Indragiri Hulu Regency. This research used quantitative methods, with descriptive analysis. The sample in this study were novice voters in Rengat District, Indragiri Hulu Regency, with total 1072 people. By using the Slovin formula, 91 samples were obtained. This research used primary data types. The analytical tool used in this study is by using Simple Linear Regression Analysis with the help of SPSS version 20. The results of this study indicate that the level of education has a correlation with the participation of novice voters in Rengat District, Indragiri Hulu Regency.

 

Keywords: Level Education, Novice Voter Participation, Election
PENGARUH KOMPENSASI DAN DISIPLIN KERJA TERHADAP KINERJA PERANGKAT DESA UNTUK MENSUKSESKAN PENYALURAN DANA DESA DI DESA SUNGAI GUNTUNG TENGAH KECAMATAN RENGAT KABUPATEN INDRAGIRI HULU
Authors: Iskandar Yenny , Windartini Sry , Suharmiyati Suharmiyati
Published: November 2019

This research was conducted at office Desa Sei Guntung Tengah,  Kecamatan Rengat  Kabupaten Indragiri Hulu. The aim is to determine the effect of Compensation on the performance of village officials in the success of Village Fund Distribution in desa Sungai Guntung Tengah, Kec. Rengat, Kabupaten Indragiri Hulu. The results of the study obtained by linear regression equation is that SPSS knows that constant (a) is 1.361. and the coefficient of X (b) is 0.355 with a multiple regression equation is Y = 1.361 + 0.355 X. The correlation coefficient is known that (X) compensation has a relationship with (Y) the performance of village officials. This can be seen from the value of the multiple correlation coefficient R is 0.813 meaning that it has a very strong and direct relationship. and then tested with a multiple coefficient of determination (R2) is 0.661. this shows (X) compensation can contribute to the variable (Y) the performance of the village apparatus by 66.1%. And the remaining 33.9% is influenced by other variables not examined in this study. t count for compensation variable is 2.239, in table t with db 35 and significant level 0.025 is obtained 2.034. because t count (2,239)> from t table (2,034) then Ho is rejected and Ha is accepted, which means compensation has a significant influence on the performance of the village apparatus.
Locas de la limpieza y técnicas industriosas del cuerpo en una villa obrera
Authors: Galarza Bárbara
Published: November 2019

A pesar de su presencia en la vida cotidiana, la producción cultural asociada a la figura vernacular de la loca de la limpieza es un fenómeno escasamente estudiado en América Latina. Intentando contribuir a esta vacancia, con un enfoque etnográfico abordo el modo en que las mujeres de una villa obrera industrial se adiestran en técnicas corporales para convertirse en expertas en limpieza. El trabajo se divide en tres partes. Primero, defino la instrucción en estas técnicas corporales como una práctica encarnada que aparece asociada al malestar. Segundo, describo ciertas instancias en las que las mujeres aprenden a limpiar. Tercero, demuestro que la educación en la limpieza se considera satisfactoriamente adquirida cuando, luego del aprendizaje táctil, olfativo y visual, las mujeres adquieren disposiciones que les permiten sentir la mugre en el cuerpo. Finalmente, vinculo esta identidad al sistema productivo en el que es vivida como una praxis social.
Metodologías. Ni en encontra ni a favor, todo lo contrario
Authors: Ramos Alcida Rita
Published: November 2019

El espinoso asunto de la metodología ha perseguido a muchos especialistas de las ciencias sociales, entre ellos los antropólogos. Difícil de definir, el método suele ser confundido con las técnicas de investigación; por ejemplo, tanto estudiantes como profesionales proponen con frecuencia que la observación participante es su “método” privilegiado. No obstante, hay grandes diferencias entre método y técnica. El método es, básicamente, una guía, un organizador de los procedimientos de la investigación. Al mismo tiempo, el método revela las inclinaciones de los investigadores hacia sus objetos. Este texto comenta sobre el uso de la metodología, presenta casos excepcionales de su uso apropiado, y propone contraejemplos de metodologías indígenas que subrayan maneras indígenas de hacer investigación, comúnmente permeadas por historias de subyugación, humillaciones, violencia generalizada y deshumanización infligidas a pueblos no occidentales que se cruzaron en el camino de la expansión y conquista occidental.
ROLE OF BERA IN EVALUATION OF HEARING LOSS IN PEDIATRIC AGE
POPULATION
Authors: Teharia Rajendra K. , Sharma* Rukmini , Purohit N .C. , KUMAR Jayant
Published: November 2019

Introduction: Hearing impairment in pediatric population specially in early age could affect their
learning abilities, skills and communication. Early diagnosis is utmost important in these cases to
prevent this disability permanently.
Aims: In this study, we evaluate the role of BERA in early diagnosis of hearing impairment specially in high risk pediatric
population.
Materials and methods: A total 65 high risk cases below 12 years of age are included in the study and BERA was obtained and
data obtained and analysed.
Results: In our study, 40.9 % cases showed hearing impairment on BERA investigation. Severe to modied hearing loss was
found in 2 4 cases (88.9 %).
Conclusion: In our study, BERA is very simple, useful, reliable, screening tool specially in high risk and un-cooperative pediatric
population for early diagnose and management of hearing loss.
CONVERGES OF SKY YOGA AND KAYAKALPA
ON THE CORE MUSCLE STRENGTH AND
AGEING FACTOR
Authors: Krishnaveni K. , Jothilakshmi* M.
Published: November 2019

INTRO: Today's generation children are growing faster in all aspects mentally,physiologically and physically too than
before generation.The life span of the human being got reduced to averagely 63 age,value tells more than the words and
What will be the future? Are the children are not going to see their grandfather and grandmother? These are the question
which lead this study to overtaken.
METHOD:The college boys from in and around Coimbatore were selected as subjects for the propose of study.The total
60 subjects were selected and they age in 18 to 21 years.Then subjects were divided into three groups,each containing
20 members.Experimental Group I given SKY yoga with Kayakalpa training and Experimental Group II were given only
SKY yoga training for 5 days in week for 10 weeks and control group not given any training.
RESULTS:The study shown that there was improvement in the coordination of hand- mind and ability to think measured
by Shuttle cross pick-up test method to the Experimental groups I & II than the subjects in control group. The
coordination of hand- mind has increased this shown that SKY yoga effects the neurological system and mental ability of
the body.
CONCLUSION: The result shown that SKY Yoga with Kayakalpa on college students has positively impact on the core
muscles and ageing factor
A STUDY ON ACADEMIC ACHIEVEMENT
AMONG HIGH SCHOOL TEACHERS
Authors: Barathi C.
Published: November 2019

The present study is carried out by differential analysis to know the difference between Academic Achievement among
High School Teachers. Three hundred High School Teachers had been randomly selected for the present study.
Normative survey method was used to collect the data. The study was done in Cuddalore District in Tamilnadu. In the
study it is found that there is significant difference among high school teachers in Academic achievement with respect to
gender.Also it is found that there is no significant difference among high school teachers in Academic achievement with
respect to subject
BEHAVIOUR PROBLEMS AMONG CHILDREN
Authors: Babu D. , Reddy B. Govinda
Published: November 2019

An attempt was made in the present investigation to study the behaviour problems among children. Sample for the
present study consists of thirty (30) parents, both fathers and mothers and their children with problem behavior in
Chittoor of Andhra Pradesh State.Achenbach Child Behavior Check List (1991) was designed to empirically assess the
behavior problems of children ranging 6-18 ages and 't' tests were used to analyse the data. Findings of the study
revealed that gender and locality have significant differences in behaviour problems among children.
ENCHANCED RECOVERY AFTER COLECTOMY :
OPIOID FREE ANESTHESIA VERSUS OPIOID
BASED ANESTHESIA
Authors: Martinetti* Andrianimaro Florelia , Parfait Razafindraibe Faneva Angelo , Rabenjari Rabenjari , Sébastien Oger , François Sztark
Published: November 2019

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programmée.Annales Françaises d’Anesthésie et de Réanimation 33 (2014)
370–384.
2. Sophie BLANCHARD et coll. Programmes de réhabilitation rapide en
chirurgie:état des lieux et perspectives - Note de cadrage.HAS / Service des
bonnes pratiques professionnelles / juillet 2014.
3. Opioid free anesthesia (OFA) ou anesthésie sans morphinique.SOFIA 2017.
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5. P. Ziemann-Gimmel. Opioid-free total intravenous anaesthesia reduces
postoperative nausea and vomiting in bariatric surgery beyond triple
prophylaxis.British Journal of Anaesthesia 112 (5):906–11 (2014).
6. Blaudszun G, Lysakowski C, Elia N, Tramer MR. Effect of perioperative
systemic alpha2 agonists on postoperative morphine consumption and pain
intensity: systematic review and meta-analysis of randomized controlled
trials.Anesthesiology 2012;116:1312-22.
7. Frauenknecht J, Kirkham KR, Jacot-Guillarmod A and al. Analgesic impact of
intra-operative opioids vs. opioid-free anaesthesia: a systematic review and
meta-analysis. Anaesthesia. 2019 May;74(5):651-662. doi: 10.1111/
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combined with desflurane for bariatric surgery.J Clin Anesth 2006;18:24–8.
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11. Mefkur Bakana,, Tarik Umutoglua, Ufuk Topuza and al. Opioid-free total
intravenous anesthesia with propofol, dexmedetomidine and lidocaine
infusions for laparoscopic cholecystectomy: a prospective, randomized,
double-blinded study.Rev Bras Anestesiol.2015;65(3):191-199
12. Marret E, Rolin M, Beaussier M, Bonnet F. Meta-analysis of intravenous
lidocaine and postoperative recovery after abdominal surgery. British
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ROSNet: A WMN based Framework using UAVs and ground nodes for Post-Disaster Management
Authors: Roy Neelabhro , Debarshi Sauranil , Sujit P.B.
Published: November 2019

Communication breakdowns during natural disasters can significantly restrict disaster management operations. Furthermore, cellular networks may also be unreliable in such scenarios. Hence, establishing communication using alternative means is of importance in these scenarios.

In this paper, we propose a prototype system to establish communication using wireless mesh network, through the use of stationary and mobile ground nodes, and aerial nodes using unmanned aerial vehicles (UAVs). This network is ad hoc and establishes connectivity without the usage of a cellular network or internet. Our system provides a complete end to end architecture, where we deploy an android application on smartphones at the user-end, the ad hoc network comprising of stationary and mobile nodes, and a graphical user interface (GUI) at the base station that facilitates situational awareness. We use the Robot Operating System (ROS) as the middleware for message synchronization between the nodes as well for UAV control. We evaluate the system for different system configurations by using UAVs and a semi-autonomous car. Our experimental results show that the system could be indispensable in providing large scale connectivity.
A REVIEW OF MULTI HOMING AND ITS ASSOCIATED RESEARCH AREAS ALONG WITH INTERNET OF THINGS (IOT)
Authors: Natarajan Krishnaraj , S Smys
Published: November 2019

With the ever increasing research in communication technology, smart systems and gadgets are emerging at a very fast pace. A recent trend is the research in internet of things (IoT) which facilitates access of information and services at any point of time around the globe thus elevating the process of digitization to a new era. Multi homing is a concept which facilitates connection of a user over multiple networks. These networks may be heterogeneous or homogeneous. This concept of multihoming acts as a strong backbone to wireless sensor networks where routing of information over the links and channels is quite a critical process. The routing of information from source to destination defines the overall accuracy of the entire wireless network. This efficiency largely dictated by an efficient routing process is influenced by many factors which include node efficiency, node lifetime, and the characteristics of the link between the nodes.
ENERGY EFFICIENT MULTI-TIER SUSTAINABLE SECURE ROUTING PROTOCOL FOR MOBILE WIRELESS SENSOR NETWORKS
Authors: S. Raj Jennifer , S Smys , Bashar Abul
Published: November 2019

The advanced progress in wireless communication pays attention on information of more sensitivity to be delivered to its destined end with numerous of restrains, such as reliableness, constancy, response time and safety. The advancements in digital gadgetry, the usage of unwired transceivers and microcontrollers has made viable the integration of sensing and computing device with transceivers and power units to form a single unit called sensor nodes, the enveloping of sensor nodes form wireless sensor nodes. Innumerable existing proposals have aimed at the energy efficient and secure transmission of data but have achieved any one at the cost of the other. Noting down the issues of the existing method this paper proposes an energy efficient multi-tier sustainable secure routing protocol (EEMSR) for mobile wireless sensor nodes which is a cohabit of multi-tier secure routing with an AL (Ant Lion) optimizer (CoMSR-ALO) along with the prime curve cryptography supported by the routing formed in spherical structure. This better encryption and decryption method takes the edge of power consumption and offers control over the utilization of energy which is difficult to be achieved when dispatching the pack and also avoids the intervention of the encroacher and improves the security and minimizes the deprivation caused due the information lost.