bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Study of Human and Murine Aortic Biomechanics and Hemodynamics in Vascular Aging
Authors: Hopper Sara E. , Cuomo Federica , Ferruzzi Jacopo , Burris Nicholas S. , Roccabianca Sara , Humphrey Jay D. , Figueroa C. Alberto
Published: October 2021

Introduction: Aging has many effects on the cardiovascular system, including changes in structure (aortic composition, and thus stiffening) and function (increased proximal blood pressure, and thus cardiac afterload). Mouse models are often used to gain insight into vascular aging and mechanisms of disease as they allow invasive assessments that are impractical in humans. Translation of results from murine models to humans can be limited, however, due to species-specific anatomical, biomechanical, and hemodynamic differences. In this study, we built fluid-solid-interaction (FSI) models of the aorta, informed by biomechanical and imaging data, to compare wall mechanics and hemodynamics in humans and mice at two equivalent ages: young and older adults.

Methods: For the humans, 3-D computational models were created using wall property data from the literature as well as patient-specific magnetic resonance imaging (MRI) and non-invasive hemodynamic data; for the mice, comparable models were created using population-based properties and hemodynamics as well as subject-specific anatomies. Global aortic hemodynamics and wall stiffness were compared between humans and mice across age groups.

Results: For young adult subjects, we found differences between species in pulse pressure amplification, compliance and resistance distribution, and aortic stiffness gradient. We also found differences in response to aging between species. Generally, the human spatial gradients of stiffness and pulse pressure across the aorta diminished with age, while they increased for the mice.

Conclusion: These results highlight key differences in vascular aging between human and mice, and it is important to acknowledge these when using mouse models for cardiovascular research.
The Discriminatory Potential of Modern Recruitment Trends—A Mixed-Method Study From Germany
Authors: Kroll Esther , Veit Susanne , Ziegler Matthias
Published: October 2021

People from marginalized groups are often discriminated against in traditional recruitment processes. Yet as companies faced with skill shortages change their recruitment strategies, the question arises as to whether modern recruitment trends such as the use of professional social network sites, active sourcing, and recruitment assignment to external agencies are affected by implicit or explicit discrimination. In our mixed-method study, we first conducted expert interviews with different types of recruiters to explore the potential for discrimination in the modern recruitment process. We then analyzed panel data from the Institute for Employment Research (IAB) in Germany to see whether there is quantitative evidence of discrimination in modern recruitment. A content analysis of the interviews shows that active sourcing and assignment of recruitment to private agencies are potentially affected by explicit discrimination. We identified three sources of discrimination in personnel selection: recruiters’ own attitudes, explicit instructions from managers, and the recruiters’ assumptions regarding companies’ preferred candidates. The results of mixed multilevel analyses with the company as a second level resonate with the qualitative findings: companies actively approach female employees, older employees, and employees who are born in Southern/Eastern Europe less often and offer women jobs less often. The effects for gender were still significant when we included far-right voting as a moderator variable on the employee level, but the interactions were not significant. Effects for gender and older people in active sourcing were also significant and robust when controlling for income, number of children, level of school completion, and educational background. Our findings suggest that current legislation may be insufficient to protect candidates who belong to marginalized groups from discrimination in modern recruitment.
Deltamethrin Microencapsulation in Emulsion Paint Binder and Its Long-Term Efficacy Against Dengue Vector Aedes aegypti
Authors: Acharya B. N. , Ahirwar Rajkumar , Dhiman Sunil , Yadav Kavita , Pandey Pratibha , Sukumaran Devanathan
Published: October 2021

Various control interventions have been effective in the control of arthropod vectors to a certain extent; still, sustained vector control is an existing problem globally. Insecticide-based formulations have been found to be useful, however the proper delivery of active molecules to target vectors is important. Currently, synthetic pyrethroid deltamethrin (DM) has been microencapsulated in the emulsion paint binder and evaluated for long-term effectiveness against dengue vector Aedes aegypti. Different compositions of emulsion binder were prepared by varying the content of monomer and DM. A selection was made for the composition yielding the best combination of properties like solid content, intrinsic viscosity, and DM content. Developed formulation was tested against laboratory-reared and pathogen-free Ae. aegypti mosquitoes. Encapsulation of DM in emulsion binder during polymerization showed a uniform distribution. The optimized formulation was stable and did not have a considerable plasticizing effect. Scanning electron microscopy revealed that grain-like micro crystals of DM and surfactant sodium lauryl sulfate (SDS) were uniformly distributed on the formulation surface. The best optimized formulation was highly effective against dengue vector Ae. aegypti and found to provide efficacy for up to 18 months of application. The knockdown time (KDT) values KDT10 and KDT50 were 7.4 min (95% CI: 5.6–9.1) and 22.1 min (95% CI: 19.7–24.3) respectively, whereas 24 h corrected mortality was 90% (95% CI: 82.5–97.5) after 18 months of application (T18). The probit model used to determine knockdown values did not deviate from the linearity and displayed normal distribution of knockdown % with time for different formulations (p ≥ 0.1). Presently developed DM microencapsulated emulsion binder was stable, smooth, and uniform. The binder displayed excellent anti-insect property and was capable of providing long-term effectiveness against dengue vectors Ae. aegypti. Such a formulation after field-scale evaluation could be very useful in attaining long-term protection from arthropod vectors.
El tratamiento de los trastornos agorafóbicos desde una óptica constructivista
Authors: Cionini Lorenzo , Mattei Daniela Maria
Published: October 2021

En el presente artículo se presenta un modelo de intervención psicoterapéutica con pacientes agorafóbicos. Después de analizar brevemente las características de los esquemas y de los procesos de compensación y descompensación, típicos de un sistema cognitivo organizado en sentido fóbico, se describen las diferencias entre dos tipologías de pacientes agorafóbicos que sugieren una diversa modalidad de aproximación al tratamiento. Se definen, entonces, los criterios estratégicos generales de intervención psicoterapéutica, se describen las fases en las cuales ésta se puede articular y se analizan algunas técnicas que se pueden utilizar en cada una de ellas.
La construcción narrativa de la experiencia en psicoterapia.
Authors: Villegas Besora Manuel
Published: October 2021

En los últimos años se ha empezado a notar un giro narrativo o hermenéutico en los distintos modelos de psicoterapia. De acuerdo con esta nuevo enfoque el proceso terapéutico se considera como una proceso de co-construcción del significado entre cliente y terapeuta a través de la actividad narrativa. El artículo considera la incidencia de este nuevo enfoque en los diversos modelos terapéuticos, aunque presta una especial atención a las terapias cognitivas de corte constructivista, donde este giro se ha producido con mayor intensidad.
La naturaleza autojustificativa del discurso terapéutico.
Authors: Gerhardt Julie , Stinson Charles
Published: October 2021

Debido a los problemas existentes en la determinación de la validez de los relatos de vida en la entrevista psicoanalítica, se ha utilizado el concepto de narrativa para reforzar la idea de que los relatos del cliente representan diferentes versiones de la verdad más que una verdad a priori, independiente del relato, tal como establece el modelo arqueológico de Freud. Sin embargo, aunque no se cuestiona el carácter narrativo de la historia del cliente, lo que se quiere mostrar aquí es que el discurso del cliente se estructura alrededor de la justificación -y más en concreto de las autojustificaciones.
Target Localization and Power Allocation Using Wireless Energy Harvesting Sensors
Authors: Chen Song , Liu Dunge , Zhao Yubin
Published: October 2021

As radio-frequency (RF) based wireless energy harvesting technology can provide remote and continuous power to low-power devices, e.g., wireless sensors, it may be a substitute for batteries and extend the lifetime of the wireless sensor networks. In this paper, we propose a wireless energy harvesting localization system (WEHLoc), which contains batteryless wireless sensors as anchors and an energy access point (E-AP) to transfer power to the anchors. We consider a passive target localization scenario, in which the anchors monitor the target and send the sensed ranging data back to the E-AP. Additionally, we formulate the optimal estimation accuracy problem which is a 0–1 mixed-integer programming problem and relates to the energy beam, target transmitted power, and deployed anchor density. Then, we develop the power allocation scheme of the E-AP to solve the objective. In order to reduce the complexity, we propose a heuristic method that converts the maximum estimation accuracy problem into the energy efficiency problem and use linear programming to solve them. The simulations demonstrate that WEHLoc can be massively deployed in a wide area, and the estimation error and the power consumption are relatively low.
Diffusive Mass Transfer and Gaussian Pressure Transient Solutions for Porous Media
Authors: Weijermars Ruud
Published: October 2021

This study revisits the mathematical equations for diffusive mass transport in 1D, 2D and 3D space and highlights a widespread misconception about the meaning of the regular and cumulative probability of random-walk solutions for diffusive mass transport. Next, the regular probability solution for molecular diffusion is applied to pressure diffusion in porous media. The pressure drop (by fluid extraction) or increase (by fluid injection) due to the production system may start with a simple pressure step function. The pressure perturbation imposed by the step function (representing the engineering intervention) will instantaneously diffuse into the reservoir at a rate that is controlled by the hydraulic diffusivity. Traditionally, the advance of the pressure transient in porous media such as geological reservoirs is modeled by two distinct approaches: (1) scalar equations for well performance testing that do not attempt to solve for the spatial change or the position of the pressure transient without reference to a well rate; (2) advanced reservoir models based on numerical solution methods. The Gaussian pressure transient solution method presented in this study can compute the spatial pressure depletion in the reservoir at arbitrary times and is based on analytical expressions that give spatial resolution without gridding-meaning solutions that have infinite resolution. The Gaussian solution is efficient for quantifying the advance of the pressure transient and associated pressure depletion around single wells, multiple wells and hydraulic fractures. This work lays the basis for the development of advanced reservoir simulations based on the superposition of analytical pressure transient solutions.
Mastrevirus Rep and RepA Proteins Suppress de novo Transcriptional Gene Silencing
Authors: Watanabe Kikyo , Ugaki Masashi
Published: October 2021

Transcriptional gene silencing (TGS) in plants is a defense mechanism against DNA virus infection. The genomes of viruses in the Geminiviridae family encode several TGS suppressors. In this study, we induced de novo TGS against the transgenic GFP gene encoding green fluorescent protein by expressing a hairpin-shaped self-complementary RNA corresponding to the enhancer region of the 35S promoter (hpE35S). In addition, we examined the TGS suppression activity of proteins encoded in the genome of Tobacco yellow dwarf virus (TYDV, genus Mastrevirus). The results show that the replication-associated protein (Rep) and RepA encoded by TYDV have TGS suppressor activity and lead to decreased accumulation of 24-nt siRNAs. These results suggest that Rep and RepA can block the steps before the loading of siRNAs into Argonaute (AGO) proteins. This is the first report of TGS suppressors in the genus Mastrevirus.
Spirometry Examination of Adolescents with Thoracic Idiopathic Scoliosis: Is Correction for Height Loss Useful?
Authors: Politarczyk Katarzyna , Kozinoga Mateusz , Stępniak Łukasz , Panieński Paweł , Kotwicki Tomasz
Published: October 2021

Loss of body height is observed in patients with idiopathic scoliosis (IS) due to spine curvatures. The study compared pulmonary parameters obtained from spirometry examination considering the measured versus the corrected body height. One hundred and twenty adolescents with Lenke type 1 or 3 IS who underwent preoperative spirometry examination and radiographic evaluation were enrolled. The mean thoracic Cobb angle was 68° ± 12.6, range 48–102°. The difference between the measured and the corrected body height increased with the greater Cobb angle. Using the corrected body height instead of the measured body height significantly changed the predicted values of pulmonary parameters and influenced the interpretation of the pulmonary testing results.
Simulation of 3D Electrochemical Phase Formation: Mixed Growth Control
Authors: Isaev Vladimir A. , Grishenkova Olga V. , Kosov Alexander V. , Semerikova Olga L. , Zaikov Yuriy
Published: October 2021

Processes of nucleation and growth largely determine the structure and properties of thin films obtained by electrodeposition on foreign substrates. Theoretical aspects of the initial stages of electrochemical phase formation under constant and variable overpotentials are considered in this work. Simulation of multiple nucleation with mixed (charge transfer, and diffusion) controlled growth was performed for three cases (cyclic voltammetry, potentiostatic electrodeposition, and galvanostatic electrodeposition). The influence of the bulk concentration of depositing ions and the exchange current density at the electrolyte/nucleus interface on cyclic voltammograms (CVs), transients of current and overpotential, as well as the number and size of non-interacting new-phase nuclei was analyzed. It is found that, under galvanostatic conditions, the number of nuclei decreases as the concentration of depositing ions increases due to a more rapid decrease in overpotential. The proposed model was applied to determine the diffusion coefficient, exchange current density, and transfer coefficient considering the experimental CV.
Genetic Diversity and Phylogeny of the Genus Euplotes (Protozoa, Ciliophora) Revealed by the Mitochondrial CO1 and Nuclear Ribosomal Genes
Authors: Wang Congcong , Hu Yue , Warren Alan , Hu Xiaozhong
Published: October 2021

Nuclear ribosomal and mitochondrial genes have been utilized individually or in combination to identify known species and discriminate closely related species. However, compared with metazoans, genetic diversity within the ciliate order Euplotida is poorly known. The aim of this study is to investigate how much nucleotide sequence divergence occurs within Euplotes. A total of 14 new gene sequences, comprising four SSU rDNA and 10 CO1 (including three species for the first time) were obtained. Phylogenetic analyses were carried out based on sequences of two DNA fragments from the same 27 isolates. We found that CO1 revealed a larger interspecific divergence than the SSU rRNA gene, thus demonstrating a higher resolution for separating congeners. Genetic distances differ significantly at the species level. Euplotes balteatus was revealed to have a large intraspecific variation at two loci, while E. vannus showed different levels of haplotype variability, which appeared as a polyphyletic cluster on the CO1 tree. These high genetic divergences suggest the presence of more cryptic species. By contrast, the CO1 gene showed low variability within E. raikovi, appearing as monophyletic clusters, which indicates that this species could be identified based on this gene. Conclusively, CO1 is a suitable marker for the study of genetic diversity within Euplotes, and increased taxon sampling gives an opportunity to screen relationships among members of this genus. Additionally, current data present no clear biogeographical pattern for Euplotes.
Incorporation of Ions into Nanostructured Anodic Oxides—Mechanism and Functionalities
Authors: Brudzisz Anna M. , Giziński Damian , Stępniowski Wojciech J.
Published: October 2021

Anodic oxidation of metals leads to the formation of ordered nanoporous or nanotubular oxide layers that contribute to numerous existing and emerging applications. However, there are still numerous fundamental aspects of anodizing that have to be well understood and require deeper understanding. Anodization of metals is accompanied by the inevitable phenomenon of anion incorporation, which is discussed in detail in this review. Additionally, the influence of anion incorporation into anodic alumina and its impact on various properties is elaborated. The literature reports on the impact of the incorporated electrolyte anions on photoluminescence, galvanoluminescence and refractive index of anodic alumina are analyzed. Additionally, the influence of the type and amount of the incorporated anions on the chemical properties of anodic alumina, based on the literature data, was also shown to be important. The role of fluoride anions in d-electronic metal anodizing is shown to be important in the formation of nanostructured morphology. Additionally, the impact of incorporated anionic species, such as ruthenites, and their influence on anodic oxides formation, such as titania, reveals how the phenomenon of anion incorporation can be beneficial.
In Vitro Effects of Papaverine on Cell Proliferation, Reactive Oxygen Species, and Cell Cycle Progression in Cancer Cells
Authors: Gomes Daniella A. , Joubert Anna M. , Visagie Michelle H.
Published: October 2021

Papaverine (PPV) is an alkaloid isolated from the Papaver somniferum. Research has shown that PPV inhibits proliferation. However, several questions remain regarding the effects of PPV in tumorigenic cells. In this study, the influence of PPV was investigated on the proliferation (spectrophotometry), morphology (light microscopy), oxidative stress (fluorescent microscopy), and cell cycle progression (flow cytometry) in MDA-MB-231, A549, and DU145 cell lines. Exposure to 150 μM PPV resulted in time- and dose-dependent antiproliferative activity with reduced cell growth to 56%, 53%, and 64% in the MDA-MB-231, A549, and DU145 cell lines, respectively. Light microscopy revealed that PPV exposure increased cellular protrusions in MDA-MB-231 and A549 cells to 34% and 23%. Hydrogen peroxide production increased to 1.04-, 1.02-, and 1.44-fold in PPV-treated MDA-MB-231, A549, and DU145 cells, respectively, compared to cells propagated in growth medium. Furthermore, exposure to PPV resulted in an increase of cells in the sub-G1 phase by 46% and endoreduplication by 10% compared to cells propagated in growth medium that presented with 2.8% cells in the sub-G1 phase and less than 1% in endoreduplication. The results of this study contribute to understanding of effects of PPV on cancer cell lines.
Addition of Vindoline to p-Benzoquinone: Regiochemistry, Stereochemistry and Symmetry Considerations
Authors: Ali Shamsher , Hénon Eric , Leroy Ritchy , Massiot Georges
Published: October 2021

Vindoline and catharanthine are the major alkaloids of Catharanthus roseus and are extracted in large quantities to prepare the pharmaceutically important Vinca type alkaloids vincaleukoblastine, vincristine and navelbine. The higher yield of vindoline relative to catharanthine makes it an attractive substrate for developing new chemistry and adding value to the plant. In this context, we have reacted vindoline with a selection of electrophiles among which benzoquinone. Conditions were developed to optimize the synthesis of a mono-adduct, of five bis-adducts, and of tri-adducts and tetra-adducts, several of these adducts being mixtures of conformational isomers. Copper(II) was added to the reactions to promote reoxidation of the intermediate hydroquinones and simplify the reaction products. The structures were solved by spectroscopic means and by symmetry considerations. Among the bis-isomers, the 2,3-diadduct consists of three unseparable species, two major ones with an axis of symmetry, thus giving a single set of signals and existing as two different species with indistinguishable NMR spectra. The third and minor isomer has no symmetry and therefore exhibits nonequivalence in the signals of the two vindoline moieties. These isomers are designated as syn (minor) and anti (major) and there exists a high energy barrier between them making their interconversion difficult. DFT calculations on simplified model compounds demonstrate that the syn-anti interconversion is not possible at room temperature on the NMR chemical shift time scale. These molecules are not rigid and calculations showed a back-and-forth conrotatory motion of the two vindolines. This “windshield wiper” effect is responsible for the observation of exchange correlations in the NOESY spectra. The same phenomenon is observed with the higher molecular weight adducts, which are also mixtures of rotational isomers. The same lack of rotations between syn and anti isomers is responsible for the formation of four tri-adducts and of seven tetra-adducts. On a biological standpoint, the mono adduct displayed anti-inflammatory properties at the 5 μM level while the di-adducts and tri-adducts showed moderate cytotoxicity against Au565, and HeLa cancer cell lines.
Preparation and Self-Cleaning Performance of Carbon-Based Superhydrophobic Coatings Based on Non-Fluorine and Non-Toxic Corn Straw
Authors: Wang Yanbin , Kang Lihui , Li Zhaoxia , Su Qiong , Pang Shaofeng , Liang Lichun , Wang Dian , Cao Shijun
Published: October 2021

Recently, superhydrophobic surfaces with self-cleaning ability have attracted broad research interest due to their huge potential in daily lives and industrial applications, but the use of fluorinate, toxic organic compounds, and expensive feedstocks make superhydrophobic materials a great challenge in practical application. In this study, we present a facile dip-coating strategy to prepare superhydrophobic coatings with self-cleaning properties based on a non-fluorine and non-toxic system by using eco-friendly corn straw as raw material. During this process, aromatic carbon particles with rough hierarchical structures were prepared firstly via a simple fast pyrolysis process, followed by modification with polydimethylsiloxane (PDMS) in absolute ethanol solvent to decrease the surface free energy. Research shows these natural straw-derived carbons display a microstructure of several protrusions which is similar to the lotus leave’s and the resulted coatings exhibit an outstanding superhydrophobic property with a static water contact angle (WCA) of 151.67 ± 1.36 degrees. In addition, the as-prepared coatings possessed excellent self-cleaning performance: no contaminations were observed on the surfaces after examining with sludge, calcimine, water, and common liquids such as tea, milk, soybean milk as well as ink, which have a broad range of potential application in the field of antifouling, waterproofing, and anticorrosive.
Charge-Flow Profiles along Curvilinear Paths: A Flexible Scheme for the Analysis of Charge Displacement upon Intermolecular Interactions
Authors: Sagresti Luca , Rampino Sergio
Published: October 2021

The Charge-Displacement (CD) analysis has proven to be a powerful tool for a quantitative characterization of the electron-density flow occurring upon chemical bonding along a suitably chosen interaction axis. In several classes of interesting intermolecular interactions, however, an interaction axis cannot be straightforwardly defined, and the CD analysis loses consistency and usefulness. In this article, we propose a general, flexible reformulation of the CD analysis capable of providing a quantitative view of the charge displacement along custom curvilinear paths. The new scheme naturally reduces to ordinary CD analysis if the path is chosen to be a straight line. An implementation based on a discrete sampling of the electron densities and a Voronoi space partitioning is described and shown in action on two test cases of a metal-carbonyl and a pyridine-ammonia complex.
Brownmillerites CaFeO2.5 and SrFeO2.5 as Catalyst Support for CO Oxidation
Authors: Répécaud Pierre-Alexis , Ceretti Monica , Aouine Mimoun , Delwaulle Céline , Nonnet Emmanuel , Paulus Werner , Kaper Helena
Published: October 2021

The support material can play an important role in oxidation catalysis, notably for CO oxidation. Here, we study two materials of the Brownmillerite family, CaFeO2.5 and SrFeO2.5, as one example of a stoichiometric phase (CaFeO2.5, CFO) and one existing in different modifications (SrFeO2.75, SrFeO2.875 and SrFeO3, SFO). The two materials are synthesized using two synthesis methods, one bottom-up approach via a complexation route and one top-down method (electric arc fusion), allowing to study the impact of the specific surface area on the oxygen mobility and catalytic performance. CO oxidation on 18O-exchanged materials shows that oxygen from SFO participates in the reaction as soon as the reaction starts, while for CFO, this onset takes place 185 °C after reaction onset. This indicates that the structure of the support material has an impact on the catalytic performance. We report here on significant differences in the catalytic activity linked to long-term stability of CFO and SFO, which is an important parameter not only for possible applications, but equally to better understand the mechanism of the catalytic activity itself.
Recognition of Chiral Carboxylates by Synthetic Receptors
Authors: Niedbała Patryk , Dąbrowa Kajetan , Wasiłek Sylwia , Jurczak Janusz
Published: October 2021

Recognition of anionic species plays a fundamental role in many essential chemical, biological, and environmental processes. Numerous monographs and review papers on molecular recognition of anions by synthetic receptors reflect the continuing and growing interest in this area of supramolecular chemistry. However, despite the enormous progress made over the last 20 years in the design of these molecules, the design of receptors for chiral anions is much less developed. Chiral recognition is one of the most subtle types of selectivity, and it requires very precise spatial organization of the receptor framework. At the same time, this phenomenon commonly occurs in many processes present in nature, often being their fundamental step. For these reasons, research directed toward understanding the chiral anion recognition phenomenon may lead to the identification of structural patterns that enable increasingly efficient receptor design. In this review, we present the recent progress made in the area of synthetic receptors for biologically relevant chiral carboxylates.
PROJETO OTIMIZADO DE PÓRTICOS ESPACIAIS DE CONCRETO ARMADO
Authors: Machado Christie de Vilhena Prata , Peters Franciane Conceição , Prata Magnus Carvalho de Vilhena , Mansur Webe João
Published: October 2021

O trabalho tem como objetivo apresentar resultados preliminares referentes ao projeto que visa desenvolver uma ferramenta computacional capaz de otimizar estruturas de concreto armado modeladas como pórticos espaciais, tendo como restrições os procedimentos da norma brasileira “ABNT (2014) NBR 6118: Projeto de Estruturas de Concreto”. Tal projeto consiste na implementação de um método de otimização inspirado na natureza chamado de algoritmo genético, o qual constitui-se de uma rotina de análise de estruturas baseada no Método dos Deslocamentos, e de uma sub-rotina de dimensionamento capaz de calcular a quantidade de aço necessária e verificar todas as restrições, segundo a NBR 6118. Até o momento, o algoritmo genético foi implementado e testado para minimização de funções de várias variáveis. Serão apresentados resultados referentes ao estudo do comportamento do algoritmo em função do número de variáveis de otimização, e parâmetros como número total de avaliações da função objetivo e número de indivíduos na população. Tal estudo visa analisar a adequabilidade do algoritmo genético adotado ao problema de otimização de pórticos, especialmente devido ao número de variáveis de otimização, que pode ser relativamente grande no problema proposto.
LEE KURAMI PERSPEKTİFİNDEN KIRDAN KENTE GÖÇÜN MEKANİĞİ: BURSA ÖRNEĞİ
Authors: AKYILDIZ İbrahim Ethem , ERTÜRK Emin
Published: October 2021

Türkiye Cumhuriyeti iç göçler açısından 1950’li yıllara kadar sakin bir dönem geçirmiştir. Türkiye’de iç göç hareketlilikleri 1950’lerden sonra bazı yapısal değişikliklerle başlamış, politik ve sosyolojik bağlamda değişimlerle iç göç hareketliliği hız kazanmıştır. Türkiye’nin yapısal değişimleri ile birlikte insanlar, kırlardan kentlere göç etmeye başlamıştır. Bunun yanında ilk değişimlere karşılık toplumun tepkilerinden biri şüphesiz günümüze kadar devam eden iç göç olgusu olmuştur. İnsanlar iç göç hareketlerini gerçekleştirirken gelişmiş büyükşehirlere doğru yönelmişlerdir. Bursa şehri iç göç açısından her zaman tercih edilen, gelişmiş büyük şehirlerden biri olmuştur ve hala da ilk tercih edilen illerin başında gelmektedir. Bu çalışmada amaç Bursa’ya gerçekleşen iç göç hareketinin altında yatan temel faktörleri belirlemek olmuştur ve bu da Lee Kuramı Perspektifinden analiz edilmiştir. Anket yoluyla elde edilen bilgiler sonucunda Bursa’ya göçe neden olan temel faktörün % 76,8 ile ekonomik olduğu, gelinen yerdeki itici faktörün % 52,9 ile işsizlik olduğu ve varılan yerdeki çekici faktörün % 47,4 ile daha iyi iş imkanları ve yüksek ücret olduğu bulunmuştur. Gelinen yer ile iç göçe neden olan temel faktörler arasında, varılan yer ile çekici faktörler arasında ve gelinen yer ile itici faktörler arasında istatistiksel olarak anlamlı birer ilişki bulunmuştur.
Improving the Quality of Life of Patients with Headache Treated with Neural Therapy
Authors: Nassar Tobón Andrea Catalina , Geney María Cristina , Martínez Pacheco Fabio Heliodoro , Vinyes David , Muñoz-Sellart Montserrat
Published: October 2021

Primary headaches (PHs) are common health complaints with a high impact on health-related quality of life (HRQOL). Treatment is multifactorial, including pharmacological and non-pharmacological strategies. Neural therapy (NT) is a regulatory treatment system that uses local anesthetic injections in chosen points to treat pain. This study aims to evaluate the effect of NT on the HRQOL of patients with PHs. Quasi-experimental prospective study involving 93 patients treated. The impact on HRQOL was evaluated through the SF-36 health, before and after treatment. Seven out of the eight items measured on the SF-36 scale improved after the intervention (p<0.001).
Problems of modern philosophy teaching within the context of general psychology
Authors: Шелковников А.Ю.
Published: October 2021

в статье говорится о необходимости психологической пропедевтики для преподавания философии в системе высшего образования. В качестве образца рассматривается система преподавания психологии и философии выдающегося русского философа Г.И. Челпанова (1862–1936). Статья может представлять интерес для философов, психологов, педагогов, студентов и аспирантов.

the article leads on the need for psychological propaedeutics for teaching philosophy within the higher education system. The system of psychology and philosophy teaching used by the outstanding Russian philosopher G.I. Chelpanov (1862–1936) has been studied as a model. The article may be of interest to philosophers, psychologists, educators, as well as undergraduate and graduate students.
Skin dryness in the Elderly Staying in a Nursing Homes and Affecting Factors
Authors: EFE ARSLAN Dilek , AYDIN AKBUGA Gökçen , KILIÇ AKÇA Nazan
Published: October 2021

Objective: This study is a descriptive study conducted to examine skin dryness, pH level, skin turgor and the affecting factors in the elderly staying in nursing homes. Method: The study population was composed of 53 elderly who stayed in a care and rehabilitation center. 50 elderly who met the participant selection criteria and who gave their consent to participate were included. Elderly Information Form and devices that measure skin moisture and pH were used as the data collection tools. Descriptive statistics, Man-Whitney U test and Spearman correlation test were used. Results: The results of the study revealed that the rate of arm dryness in the female elderly was higher compared to the male elderly and that skin turgor duration was longer in the elderly with cardiovascular diseases. When the relationship between water-fluid consumption of elderly and skin turgor duration was examined, it was seen that the duration of skin turgor extends as water-fluid consumption decreases. Conclusion: Dry skin was observed in all the elderly staying in the nursing homes; the duration of skin turgor extended; and skin pH was at normal levels. It was further revealed that daily water-fluid intake of the elderly affected the duration of skin turgor.
Determinants Model in Reducing HIV-Related Stigma in Health care Workers: A Systematic Review
Authors: Handayani Sri , Maidin Alimin , Birawida Agus Bintara , Suriah Suriah , Ansariadi Ansariadi , Indriasari Rahayu , Stang Stang
Published: October 2021

Background: The stigma accepted by people living with HIV (PLWHA) is a major obstacle in HIV prevention, especially from health workers.
Aims: This study aims to determine the factors associated with HIV stigma among health workers.
Methods: This systematic review was conducted using the 2015 PRISMA guidelines. All publications by reading the title and abstract. In the final screening stage, the authors read the full text of the remainder of the article and held back studies that were consistent with inclusion criteria, focusing on HIV-related stigma determinants published in 2010-2020.
Results: The stigma that comes from health workers to PLWHA can come from personal beliefs or a lack of personal confidence, which can be derived from self-confidence, self-confidence, knowledge, working time, and institutional support or policies from the workplace that create discriminatory behavior when dealing with PLWHA. The created stigma can reduce social interactions and the quality of life of PLWHA.
Conclusion: It is important to find determinants to formulate appropriate intervention plans in reducing HIV-related stigma, especially among health workers.
Assessment of Serum Ionized Calcium in the Perioperative Period in Patients Undergoing Total Thyroidectomy
Authors: Fuad Muqdad , Modher Ahmed
Published: October 2021

BACKGROUND: The serious complications of total and near-total thyroidectomy vary from hypocalcemia to recurrent laryngeal nerve injury to tension hematoma. Post-operative hypocalcemia is common and has an incidence of 1.3–83% in some studies.

AIM: The aim of the study is to evaluate the immediate post-operative sequence of serum-ionized calcium next to entire or close entire thyroidectomy to describe the incidence degree of hypocalcemia.

METHOD: One hundred and seventy-four (174) patients who underwent total and near-total thyroidectomy were investigated for serum-ionized calcium level preoperatively and on post-operative day (POD) 1 and 2, searching for difference in serum-ionized calcium level preoperatively.

RESULTS: There was a significant difference between pre-operative serum-ionized calcium (Ca++) level and that in POD1. The mean pre-operative ionized Ca was 1.23 ± 0.47 mmol/l, while mean ionized Ca on POD1 was 1.175 ± 0.11 mmol/l proposing decrease in mean of ionized Ca++ in POD1 (p = 0.0001). There was also a significant difference between pre-operative serum-ionized Ca++ level and that in POD2. The mean pre-operative ionized Ca was 1.23 ± 0.47 mmol/l, while the mean of ionized calcium on POD2 was 1.177 ± 0.1 mmol/l suggesting decrease in mean concentration of Ca++ in POD2 (p = 0.0001).

CONCLUSION: Significant number of patients who undergo near-total and total thyroidectomy develop decrease in the serum concentration of calcium postoperatively.
The Role Vascular Endothelial Growth Factor, Control Glycemic, Lipid Profile, and Hypoxia-inducible Factor 1-Alpha at Type 2 Diabetic Patients in North Sumatera, Indonesia
Authors: Rusdiana Rusdiana , Widjaja Sry Suryani , Amelia Rina , Syarifah Siti , Rusmalawati Rusmalawati
Published: October 2021

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder whose prevalence continues to increase worldwide. Chronic hyperglycemia increases the area of hypoxia that can be measured by markers of hypoxia-inducible factor 1-alpha (HIF-1α) and endothelial cell damage by vascular endothelial growth factor (VEGF) secretion and the association of the course of diabetes mellitus, dyslipidemia is also a risk factor that can aggravate the condition. diabetes mellitus.

AIM: The aim of this study was to correlate VEGF with HIF-1α and other metabolic markers in T2DM.

METHODS: Examination such as blood pressure, height, and body mass index, and duration of diabetes were recorded. Laboratory examination like blood sugar levels and glycated hemoglobin (Hba1C) levels, lipid profile such as cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides were evaluated by Paramitha Laboratory Clinic and VEGF and HIF-1α we examined by ELISA methods in the Integrated laboratory of Medical Faculty, Universitas Sumatera Utara. The study was done by cross-sectional analytic methods, among 135 patients with T2DM who were admitted from the various primary health-care centers in Medan city and surrounding areas in North Sumatera. The inclusion criteria of the samples were all the patients diagnosed with T2DM, both the sexes, and the exclusion criteria of the samples with T1DM and severe disease. The data of the samples were processed using a computer with the SPSS program.

RESULTS: There was a positive significant correlation between VEGF with HIF-1α, with a strong correlation, and found a negative correlation between VEGF with fasting blood sugar and HDL (p < 0.005).

CONCLUSION: By finding strongly and positive correlation between VEGF and HIF-1α, the samples of menunjukkan bahwa peningkatan konsentrasi VEGF meningkat selaras dengan peningkatan konsentrasi dari HIF-1α _dan ini menunjukkan bahwa proses angiogenesis pada sample sedang berlangsung sebagai mekanisme kompensasi pertahanan vascular.
Problem-oriented Teaching Mode based on Data Mining Technology in the Sports Psychology Classroom
Authors: Zhang Guomeng , Chen Siyuan
Published: October 2021

Sports psychology is a branch of psychology and is a sports course that takes both theory and practice into account. It is not only an integral part of the talent training curriculum system of sports colleges and universities, but also a basic compulsory course for social sports majors in comprehensive universities. Sports psychology has currently become one of the significant theories in PE teaching, which not only guides PE teaching, but also helps solve existing problems in PE teaching and drives the development of PE teaching. Subject to the impact of traditional education mode and educational concept, etc., however, there are some problems in the existing the teaching of sports psychology, such as students’ low interest, poor initiative and poor educational effect. To raise students’ learning interest, this paper selected a problem-oriented modular teaching mode, and applied it to the sports psychology classroom, to improve the learning effect. In this study, we first used data mining technology to build an anxiety prediction model and then identified a problem to be solved. After that, the problem was designed and analyzed, the known problem was confirmed, new information was collected, old and new knowledge was integrated, until the problem was finally solved. On this basis, based on virtual simulation technology, an experimental simulation teaching system for sports psychology was presented. It was found through research that the problems-oriented teaching mode can significantly enhance the effect of sports psychology and PE teaching and increase students’ learning initiative. The learning effect was significantly better than that of traditional teaching methods.
Combinations of Practical Integration Strategies Used in Mixed Methods Information Studies
Authors: Pluye Pierre , Granikov Vera
Published: October 2021

Mixed methods, integrating qualitative (QUAL), and quantitative (QUAN) methods (e.g., research questions, data collections and analyses, and results) in empirical studies and program evaluations are becoming increasingly popular for answering complex questions. Several strategies for integrating QUAL and QUAN phases, results, and data have been proposed over the years, but their conceptualization is usually design-driven, or fragmented, or not empirically tested. In addition, researchers, graduate students, and professionals using mixed methods find it difficult to plan, conduct, and report the application of these strategies simply and clearly. In this chapter, the authors will present nine practical strategies and several combinations of strategies, illustrated with published mixed methods studies in information science. This chapter contributes to advance methodological knowledge on mixed methods in information science and calls for better reporting of mixed methods studies and integration strategies specifically.
Fabrication of Platinum/ Polypyrol-Carbon Nanofiber Nanocomposite Electrocatalyst for Direct Methanol Fuel Cells
Authors: Yaldagard Maryam , Nazoktabar Mariyeh , Jahanshahi Mohsen
Published: October 2021

A novel electrocatalyst has been developed based on polypyrol-carbon nanofiber (PPy-CNF) support material to increase the stability of Pt/ PPy-CNF/GDL electrocatalyst in direct methanol fuel cell (DMFC). A novel conducting polymer (PPy)-CNF nanocomposites was prepared by a solution dispersion technique and used to support platinum nanoparticles. For preparation of catalyst ink, 20 wt.% Pt/PPy-CNF electrocatalyst with a platinum loading of 0.4 mg cm-2 was prepared by ethylene glycol (EG) method. Physical and electrochemical properties were analyzed by X-ray diffraction (XRD), Fourier transform infrared (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM) imaging and cyclic voltammetry (CV) experiments. FTIR results prove the existence of PPy in the support. SEM images showed that the one–dimensional CNFs were efficaciously covered by PPy. The TEM characterization revealed that the fine Pt nanoparticles prepared by polyol method were dispersed on the surface of the electrocatalyst successfully. XRD patterns also revealed that the mean size of Pt crystal nanoparticles was about 3.69, 6.51 and 2.91 nm for Pt/PPy-CNF, Pt/CNF and Pt/C electrocatalyst respectively. The size of the PPy on carbon paper has been measured in the range of 35-40nm by AFM. Based on the electrochemical properties and acceleration tests evaluated by cyclic voltammetry measurements and Chronoamperometric experiments it was found that the as prepared Pt/PPy-CNF/GDL electrode exhibited a comparable electrochemical surface are (ECSA), MOR activity and so stability (in the presence of methanol) with respect to the Pt/CNF /GDL and Pt/C/GDL commercial one. A rather significant reduction in the peak potential of methanol electro-oxidation from 0.69V for Pt/C/GDL to 0.76V for Pt/PPy-CNF/GDL electrode indicates that an increase in the activity for MOR is achieved by replacing the C by PPy-CNF. The corresponding ECSA values for the Pt/PPy-CNF/GDL, Pt/CNF/GDL and Pt/C/GDL electrodes were 108.69, 53.93 and 17.98 m2g-1 respectively.
Growth Optimization and Study on Structural, Morphological, Optical and Electrical Properties of As-Deposited Zinc Sulfide Thin Films Fabricated by Radio-Frequency Magnetron Sputtering Technique at Room Temperature
Authors: Bashar Muhammad Shahriar , Matin Rummana , Sultana Munira , Siddika Ayesha , Gafur M.A. , Farid Ahmed
Published: October 2021

The deposition of Zinc Sulfide (ZnS) thin films is optimized using a radio-frequency (RF) magnetron sputtering technique with variable RF power to minimize deposition steps and lower the fabrication costs. Room temperature as-deposited film growth optimization is conducted by studying their structural, morphological, optical, and electrical properties. The target power and deposition rate were related by a slope of 0.1648 and a linear correlation coefficient (R) of 0.9893. Only one significant peak for the films in the XRD pattern indicated that the films are of a single crystalline structure. All the deposited thin films exhibited a ZB structure. It is observed that the micro-strain ranged from 36.00x10-3 to 4.14x10-3, and that of dislocation density ranged from 6.68 to 0.08 Line/cm2. The optical energy band gaps of as-deposited ZnS films at different deposition power were found from 3.31 to 3.37 eV. The average transmittance percentage was increasing from 71.63% to 84.29%, above 400 nm wavelength. The films exhibited n-type conductivity with bulk carrier density in the order of 1012 cm-3. The carrier concentration and mobility ranged from 2.84x1011 to 3.98x1012 cm-3 and 1.06 to 27.68 cm2/Vs, respectively. The minimum and maximum resistivity of 1.01x104 and 2.52´105 Ω-cm were noted for the film deposited at 90 and 60W power, respectively.
Case Report: Human Bertiellosis—A Rare Cestode Infection in a South African Child
Authors: Naranbhai Nitesh , A. Singh Rochelle , Moodley Bhavani , Han Khine Swe Swe , Archary Moherndran , Mvelase Nomonde
Published: October 2021

Cestodes of Bertiella genus are parasites of nonhuman primates. We describe a rare case of human bertiellosis in South Africa: a 3-year-old girl with a 1-year history of rectal proglottid discharge and intermittent abdominal pain. After repeated failure with benzimidazole antihelminthic treatment, praziquantel proved successful.
The Archaeology of Garlic (Allium Sativum)
Authors: Sarpaki Anaya
Published: October 2021

Recent finds of garlic from Late Bronze Age Akrotiri, Thera have led to research related to the historical, economic and social aspects of its use in the archaeological narrative. Garlic is an important domesticated plant in our lore, medicine, mythology, cooking, and ethnography, and is now ubiquitous in everyday use. Previously, we knew of its importance in historical periods, especially since Roman times, when its use extended to all of Europe and beyond. Archaeobotanical investigations have extended the prehistoric and historical knowledge of this crop, providing some evidence as to how it was regarded, what were its possible uses and its changing status, diachronically. Here, therefore, it is an attempt to provide an overview of the related archaeological finds and, briefly, its references in ancient texts.