bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostic Value of Contrast-Enhanced Digital Mammography Versus Contrast-Enhanced MRI for Detecting Residual Disease After Neoadjuvant Chemotherapy for Breast Cancer
Authors: Kim Eun Young , Park Chan Heun , Kook Shin Ho
Published: December 2022

Purpose: Preoperative evaluation of breast cancer using contrast-enhanced digital mammography (CEDM) has gained acceptance as a possible alternative to contrast-enhanced magnetic resonance imaging (CEMRI). We aimed to compare the diagnostic performance of CEDM and CEMRI for chemotherapeutic response in breast cancer patients who underwent neoadjuvant chemotherapy (NAC).Methods: Fifty patients with invasive carcinoma who underwent both CEDM and CEMRI from November 2017 to October 2018 were included. The residual malignancy sizes after NAC were compared with the histopathological results. The diagnostic performance for detecting residual cancers was compared using Lin concordance and Pearson correlation coefficients.Results: Fifty patients were included in this analysis. The mean tumor size after NAC was 1.22 cm (range: 0–7.0) for CEDM and 1.13 cm (range: 0–5.1) for CEMRI compared with 1.89 cm (range: 0–12.0) at the final pathology measurement. The sensitivity for identifying residual lesions for CEDM and CEMRI were 62.5% (95% confidence interval [CI]: 40.6–81.2) and 66.7% (95% CI: 44.7–84.4), respectively. The positive predictive values for residual lesions were 93.8% (95% CI: 69.8– 99.8) for CEDM and 88.9% (95% CI: 65.3–98.6) for CEMRI. The mean difference in CEDM was 0.668 cm, with a concordance coefficient of 0.202 and Pearson correlation coefficient of 0.231 (p=0.220).Conclusion: The diagnostic value of CEDM for detecting the residual tumor extent after NAC was comparable to that of CEMRI.
Ein Blick zurück nach vorn: 50 Jahre Engagement für Umwelt- und Nachhaltigkeitsforschung
Authors: Stauffacher Michael , Bornemann Basil , Zingerli Claudia , Junge Xenia , Bergman Max
Published: December 2022

Knapp 100 Teilnehmende trafen sich zum 50-jährigen Jubiläum der saguf. Die Vorträge und Diskussionen betonten den reichhaltigen Erfahrungsschatz der saguf in der Umweltund Nachhaltigkeitsforschung und gaben vielfältige Impulse für zukünftige Entwicklungen.
Participatory Ecological Monitoring (PEM): Participatory research methods for sustainability ‐ toolkit #4
Authors: Andrianandrasana Herizo T. , Savage Jessica , Volahy Anselme Toto , Long Peter R. , Jones Nikoleta
Published: December 2022

Participatory Ecological Monitoring (PEM) is a conservation methodology aiming to include local communities in the collection and analysis of biodiversity and threats data in a managed conservation zone. Often implemented annually, PEM optimises local knowledge to help understand ecological
change which is an essential step towards assessing the success or failure of conservation activity and improving conservation effectiveness.
The Birth of the First Journal of Nursing Research in Jordan
Authors:   Jordan University of Science and Technology, AbuAlRub Raeda
Published: December 2022

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Comparative analysis of hybrid stabilization methods in the treatment of burst fractures of the vertebral bodies associated with osteoporosis
Authors: Rerikh V. V. , Sinyavin V. D.
Published: December 2022

Objective. To perform comparative analysis of posterior stabilization methods combined with cement vertebroplasty and osteoplasty with deproteinized bone allograft in the treatment of uncomplicated burst fractures of the vertebral bodies associated with osteoporosis.Material and Methods. The study was a retrospective analysis. Two groups of patients were formed, inclusion and exclusion criteria were determined. The follow-up period was 12 months. The magnitude of kyphosis correction according to the Cobb method, the magnitude of residual postoperative kyphotic deformity, its recurrence in the long term postoperative period, and the length of transpedicular fixationwere assessed. Sagittal balance parameters and subjective assessments of the patient’s condition were not evaluated.Results. With a statistically significant difference, it can be said that the main predictors of recurrence of local kyphosis, incomplete correction of deformity and increased pain syndrome are the level of injury (T12 vertebra), the degree of initial kyphotic deformity, incomplete achievement of its correction after surgery (>10°), and the value of T-criterion according to densitometry. The length of fixation does notaffect the loss of correction and recurrence of kyphosis, however it may correlate with the severity of osteoporosis.Conclusions. When comparing posterior stabilization methods in combination with cement vertebroplasty or osteoplasty, there was no statistical difference in clinical and radiological outcomes.
Tactics for the treatment of potential and true thoracic aorta injuries by pedicle screws in the absence of acute bleeding: analysis of a small clinical series and literature data
Authors: Aganesov A. G. , Aleksanyan M. M. , Abugov S. A. , Mardanyan G. V.
Published: December 2022

Objective. To analyse the results of treatment of patients in whom, after fixation of the thoracic spine, contact of screws with the aorta with its wall injury was revealed.Material and Methods. Three own observations and literature data were analysed.Results. Three patients with potential (1 case) and true (2 cases) injury to the thoracic aorta by a transpedicular screw underwent simultaneous surgical intervention including thoracic endovascular aortic repair (TEVAR) followed by remounting (2 cases) or removal of the transpedicular fixation system. An analysis of publications on this topic is presented.Conclusion. Intramural hematoma caused by screw malposition is an indication for aortic repair due to the risk of its dissection or rupture.It is advisable to give preference to endovascular methods of treating vascular injuries under conditions of local anesthesia as the first stage, and then to perform the revision of transpedicular fixation system under anesthesia.
Treatment of gunshot wounds of the spine using full-endoscopic surgery: analysis of a small clinical series
Authors: Gizatullin Sh. Kh. , Aliev Z. Sh. , Stanishevsky A. V. , Kristosturov A. S. , Davydov D. V. , Onnitsev I. E.
Published: December 2022

Objective. To assess the effectiveness of the treatment of gunshot wounds of the spine using percutaneous full-endoscopic technique.

Material and Methods. Three patients with gunshot shrapnel wounds of the spine were treated using percutaneous full endoscopy.

Results. The patients underwent a removal of foreign bodies (metal fragments) at the cervical, thoracic and lumbosacral levels of the spine using percutaneous full endoscopic surgery. The operations were carried out without complications, with minimal additional trauma to soft tissues and the spinal motion segment. In all three cases, there was a positive dynamics in the form of regression of the pain syndrome. There were no infectious complications.

Conclusion. The successful use of percutaneous full endoscopy in the surgical treatment of blind shrapnel wounds of the spine is shown. The results indicate the expediency of further research and development of this area to address the issue of introducing the technique into the routine practice of treating gunshot wounds both in peacetime in neurosurgical hospitals and centers of spinal neurosurgery, and in wartime at the stages of specialized care.
Non-comorbid Respiratory Factor and Work of Breathing in Pediatric COVID-19 Patient: How is Their Synergistic Correlation with the Level of Care?
Authors: Efendi Defi , Kurniasari Maria Dyah , Huda Mega Hasanul , Farid Raudha Ilmi , Rias Yohanes Andy , Prawira Yogi , Putri Nina Dwi , Utami Ayuni Rizka , Asmarini Titik Ambar , Lestari Pande Lilik , Mais Pricilia , Babakal Abram
Published: December 2022

Background: Work of breathing (WOB) and non-comorbidities factors in the respiratory system are the two probable findings in pediatric COVID-19 patients. However, the association of those factors with level of care was not well reported.Purpose: This study aimed to identify the relation between potential predictors including comorbidity, low nutritional fulfillment, infectious disease, shock, cough, O2 saturation reduction, abnormal blood gas analysis and sore throat with the level of care among pediatric COVID-19 patients. We also analyzed the synergistic correlation of non-comorbidities factors in the respiratory system and work of breathing to predict level of care in pediatric COVID-19 patients.Methods: A cross-sectional study was conducted in the six referral hospitals from July to September 2020 in four provinces in Indonesia. An observation checklist was used to collect data from the medical records of pediatric patients with COVID-19, including medical diagnosis, demographic, and clinical manifestation. This study included 423 participants aged from 0 to 18. The multivariate logistic regression was performed to test the adjusted odds ratios (AORs) with the 95% confidence intervals (CIs) of the association between WOB, non-comorbid respiratory, and level of care. Moreover, dummy variables (2x2) were made to analyze synergistic correlation of non-comorbid respiratory disease and WOB. The AOR with the 95% CIs was applied in the association between the complication of non-comorbid respiratory diseases and high work of breathing with level of care among pediatric patients with COVID-19.Results: Results showed that age, presence of comorbidity, nutritional fulfillment, infectious disease, shock, work of breathing, O2 saturation reduction, abnormal blood gas analysis, sore throat, and convulsive meningeal consciousness were significantly associated with the level of care (p<0.05). Pediatric patients with non-comorbid respiratory and increased work of breathing had a 15.59 times higher risk of requiring PICU care level (p<0.01). Meanwhile, pediatric patients who experienced both non-comorbid respiratory and increased work of breathing had a 5.76 times risk of requiring an intermediate level of care (p<0.05), and 9.32 times higher risk of requiring a PICU level of care (p<.05).Conclusion: It was found that both non-comorbid respiratory and increased WOB had a significant relationship with the level of care for pediatric patients with COVID-19. Nurse should take into account those clinical findings to increase the awareness in monitoring clinical deterioration in pediatric COVID-19 patients.
The Effect of Pelvic Rocking Exercise with a Birth Ball and SP6 Acupressure on Duration of the First and Second Stage of Labor
Authors: Karningsih Karningsih , Purwanti Dwi , Yulfitria Fauziah , Sari Gita Nirmala , Nuraenah Een
Published: December 2022

Background: Long duration of labor increases the pain that a mother experiences. Several non-pharmacological methods, such as pelvic rocking exercises and SP6 acupressure, have been discovered to reduce pain and accelerate labor duration. It needs to be clarified which of the two methods is more effective.Purpose: This study aimed to assess the effectiveness of pelvic rocking exercise with a birth ball and SP6 acupressure in shortening the duration of the active phase in the first and the second stage of labor.Methods: This study used a quasi-experimental design involving 64 mothers in the first stage of normal delivery who were recruited using propensity score matching sampling. The participants were divided into two intervention groups (the pelvic rocking exercise with a birth ball and SP6 acupressure). Each respondent in the two intervention groups was monitored for progress of labor during the active phase in the first stage using a partograph starting from cervical dilatation of 4 cm to 10 cm. The duration of the second stage was assessed by calculating the length of time from cervical dilatation of 10 cm to the delivery of the entire baby. The Mann-Whitney U test was performed to assess the difference between the two interventions in the two stages of labor assessed.Results: There was a difference in the duration of labor in the first stage (p=0.00) and the second stage (p=0.001) between the groups given the pelvic rocking exercise with a birth ball and the SP6 acupressure. The pelvic rocking exercise with a birth ball was found to be more effective in shortening the duration of the active phase in the first stage (Mean rank=19.83) and the second stage of labor (Mean rank=24.56) compared to SP6 acupressure (Mean rank of the first stage=45.17 and Mean rank of the second stage=40.44).Conclusion: The pelvic rocking exercise was found to be more effective compared to SP6 acupressure in shortening the duration of the active phase in the first and the second stage of labor. Pelvic rocking exercise can be implemented to help accelerate labor duration so that mothers can feel more comfortable during the labor.
Individual Characteristics, Adherence, and Barriers to Medication Adherence of Hypertensive Patients at the Indonesia - Timor Leste Border
Authors: Berek Pius Almindu Leki , Siswanto Bambang Budi , Irawati Dewi , Jatmiko Wisnu
Published: December 2022

Background: Until the last decade, the incidence of hypertension has increased sharply. It has been reported that individuals with hypertension show a low level of adherence to their therapy management. Moreover, there has been no previous research evaluating individual characteristics, adherence, and barriers to medication adherence among people with hypertension at the border of Indonesia and Timor Leste.Purpose: This study aimed to identify individual characteristics, adherence, and barriers to medication adherence among hypertensive patients.Methods: A total of 112 hypertensive patients recruited using a quota sampling method at the border of Indonesia and Timor Leste participated in this cross-sectional study. Data were collected using the Hill-Bone Questionnaire to identify adherence and the Adherence Barrier Questionnaire (ABQ) to identify barriers to medication adherence. Individual characteristics were also collected. To confirm the hypertension condition at the time of data collection, measurements of blood pressure were retaken. Descriptive statistics and Chi-square analysis were used for data analysis.  Results: The average of systolic blood pressure was 163.85(18.24) mmHg, and the diastolic blood pressure was 99.30(11.57) mmHg. The Chi-square test showed that education and occupation had a significant relationship with adherence (p<0.05) and barriers to medication adherence (p=0.000). Meanwhile, other characteristics, including age, gender, and marital status, were not significantly related to adherence (p>0.05) and barriers to medication adherence (p>0.05).Conclusion: There is a relationship between education and occupation with adherence and barriers to medication adherence, but there is no relationship when viewed from such individual characteristics as age, gender, and marital status. Further research is needed to identify effective educational methods to increase the knowledge, motivation, and self-efficacy of hypertensive patients to improve blood pressure control.
The Effect of Mindfulness-Based Stress Reduction on Restless Legs Syndrome in Hemodialysis Patients: A Randomized Clinical Trial
Authors: Delshad Zahra , Aghajani Mohammad
Published: December 2022

Background: There is currently no definitive cure for restless legs syndrome (RLS), and the common treatments are only used to reduce symptoms. Mindfulness-based stress reduction (MBSR) is an intervention that has shown beneficial effects in many mental and physical disorders.Purpose: This study aimed to determine the effect of MBSR on RLS in hemodialysis patients.Methods: This study was a randomized clinical trial involving 60 hemodialysis patients with RLS recruited by convenience sampling each group. Inclusion criteria were patients with RLS diagnosis, age 18-65, Hb>10, no cognitive disorders, ability to read and write, no vision or hearing problems, and history of hemodialysis ≥6 months. The intervention group received eight sessions of the MBSR program, and the control group received routine care in a government dialysis center. International Restless Legs Syndrome Scale and Restless Legs Syndrome Severity Scale were used to measure RLS. Statistical analyses were conducted using independent and pair t-test and ANCOVA.Results: Significant difference was found in the severity the RLS (Mean(SD) score) between the intervention group (12.90(4.58)) and the control group (22.27(4.19)) (95% CI:-11.66 to -7.08, p<0.0001). The effect size between groups was obtained based on Cohen’s d of 2.13.Conclusion: MBSR showed a significant reduction in the severity of RLS in hemodialysis patients. This preliminary study suggests that MBSR can be a promising treatment option in the management of RLS patients.
Pengaruh Lahan Kosong terhadap Kemiskinan di Kota Bengkulu
Authors: Harmes Harmes , Juanda Bambang , Rustiadi Ernan , Barus Baba
Published: December 2022

Penataan ruang di Indonesia sudah diimplemetasikan sejak tahun 2007, namun pengaruhnya terhadap kemiskinan belum banyak dikaji dan diteliti. Sejak perda Rencana Tata Ruang Wilayah (RTRW) provinsi dan kabupaten/kota banyak ditetapkan ada kecederungan terjadi perlambatan angka penurunan kemiskinan. Penelitian ini bertujuan menelaah pengaruh lahan kosong terhadap kemiskinan. Statistik yang biasa digunakan untuk menyelidiki adanya keterkaitan secara spasial sebuah variabel penelitian adalah indeks moran, sedangkan pengaruh antar variabel yang menyelidiki sampai pada setiap unit amatan biasa digunakan ekonometrika spasial yakni regresi terboboti spasial. Hasil penelitian menunjukkan bahwa lahan kosong dan kemiskinan memiliki autokorelasi spasial yang mengelompok dengan nilai indeks moran masing-masing 0,203 dan 0,331. Kebaikan model dilihat dari R2 sebesar 0,218, yang berarti model ini hanya dapat menjelaskan variasi kemiskinan yang terjadi sebesar 21,8%. Pengaruh antara lahan kosong terhadap kemiskinan bergradasi secara kontinum dari bagian utara kota, pusat dan bagian selatan kota, semakin ke arah selatan pengaruhnya semakin besar. Pengaruh terkecil adalah 0.056, di Kelurahan Kandang Limun sedangkan terbesar adalah 0.342 di Kelurahan Teluk Sepang. Nilai ini menjelaskan apabila luas lahan kosong meningkat 1%, maka jumlah penduduk miskin akan bertambah antara 0,56% sampai 34,2%. Re-rata koefisien regresinya adalah 0,145 artinya rata-rata pengaruh lahan kosong terhadap kemiskinan mencapai 14,5% per kenaikan 1 % lahan.
Evaluasi Kesesuaian Lahan untuk Tanaman Jagung Di Kabupaten Biak Numfor, Papua
Authors: Malik Afrizal , Yufdy Muhammad Prama , Siska Widia , Ndaru Ratih Kusumasari
Published: December 2022

Produktifitas jagung di Papua masih tergolong sangat rendah yakni kurang dari 1,8 ton/ha. Produksi jagung dapat ditingkatkan dengan penambahan areal tanam maupun introduksi teknologi yang tepat. Namun, inovasi teknologi tidak bisa memberikan hasil terbaik jika penanaman dilakukan di lahan yang kurang sesuai, sehingga kesesuaian lahan merupakan kunci penting dalam meningkatkan produktifitas. Tujuan penelitian adalah untuk melakukan evaluasi kesesuaian lahan tanaman jagung di Kabupaten Biak Numfor, Papua. Penelitian dilakukan tahun 2015 menggunakan pendekatan penginderaan jauh dan Sistem Informasi Geografis (SIG). Data yang digunakan meliputi Citra satelit Landsat 7, Peta RBI digital skala 1:50.000 BIG, Peta Geologi, dan Digital Elevation Model (DEM). Penelitian ini terdari dari 3 tahap, tahap pertama adalah analisis parameter kesesuaian lahan, meliputi iklim, topografi dan tanah. Tahap kedua yaitu pengamatan lapang, pengambilan sampel dan analisis tanah. Analisis tanah meliputi sifat fisik-kimia tanah lengkap. Tahap ketiga yakni penilaian kesesuaian lahan menggunakan kerangka FAO (1976), pengolahannya menggunakan program Sistem Penilaian Kesesuaian Lahan (SPKL) Versi 1. Hasil analisis menunjukkan lahan di Kabupaten Biak Numfor, Papua, potensial untuk pengembangan tanaman jagung, dengan lahan potensial seluas 27.951 atau  12,76% dari total luas lahan Kabupaten Biak Numfor. Lahan sesuai meliputi lahan sangat sesuai (S1) seluas 6.777 ha (3,09%), lahan cukup sesuai (S2)  seluas 1.733 ha (0,79%) dan lahan sesuai marginal (S3) seluas 19.441 ha (8,87%). Budidaya tanaman jagung di lahan yang sesuai diharapkan dapat meningkatkan produktifitas tanaman jagung di Kabupaten Biak Numfor, Papua.
Radical scavenging activities of Kaempferia larsenii Sirirugsa extract and prominent flavonoids in its rhizomes
Authors: Theanphong Orawan , Somwong Pathom
Published: December 2022

Medicinal plants of the genus Kaempferia (Zingiberaceae) have long been valued in Thailand, where their fresh rhizomes, extracts and oils are utilized for traditional medicinal purposes. While the well-known Kaempferia plants, particularly K. galanga and K. parviflora have been scientifically proven to be effective medicinal herbs in antioxidative investigations and in a variety of pharmacological activities, K. larsenii, one of the members of this genus that is found in northeastern Thailand and has long been used by local practitioners for curative purposes, has never had the chemical constituents and antioxidant activity reported before. Thus, the purpose of this study was to determine the antioxidant capacity of the plant and the active chemical components accountable for its action. K. larsenii rhizome extract was subjected to a number of antioxidative tests, including 2,2?-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, superoxide anion and hydroxyl radical scavenging activities, as well as HPLC analyses. The HPLC method used a ZORBAX Eclipse Plus C18 column, a 1 mL/min flow rate of methanol and 0.1% (v/v) phosphoric acid (55:45) and a diode-array UV absorbance at 265 nm as the stationary phase, mobile phase and detection respectively. In the investigated assays, the plant extract exhibited remarkable antioxidant activity, with EC50 values ranging from 11.60 to 26.31 µg/mL. Its efficacy was significantly higher than that of the positive controls, which had EC50 values ranging from 13.08 to 29.91 µg/mL. According to the HPLC profile of the extract, the medicinal flavonoids kaempferol and quercetin were present in the sample at % of 12.7562 and 0.4976 (w/w) respectively. K. larsenii rhizome extract is a good source of antioxidants and has the potential to be incorporated into herbal medicinal preparations that would be beneficial for health.
A classroom-based study on the effects of WCF on accuracy in pen-and-paper versus computer-mediated collaborative writing
Authors: González-Cruz Belén , Cerezo Lourdes , Nicolás-Conesa Florentina
Published: December 2022

This study compared the effects of computer-mediated (CM) versus pen-and-paper (P&P) writing on written accuracy and feedback processing in tasks written and rewritten collaboratively following a pedagogical treatment in two intact authentic classrooms. The study involved 32 secondary education low-proficiency English-as-a-foreign-language (EFL) learners writing two descriptive texts collaboratively and receiving in-class training in the identification and correction of grammatical, lexical, and mechanical errors. Participants were provided with unfocused direct error correction (EC). Error logs were used to facilitate noticing of teacher corrections (i.e., feedback processing). Dyads were required to rewrite their texts for evidence of feedback uptake. Results indicate that writing collaboratively on the computer with the availability of the Internet contributes to increased grammatical and lexical accuracy. No differences were found between writing environments regarding feedback processing or accuracy of rewritten texts.
Heritage, second and third language learner processing of written corrective feedback: Evidence from think-alouds
Authors: Bowles Melissa A. , Gastañaga Kacie
Published: December 2022

This study compares the processing of three different types of written corrective feedback (WCF) by heritage language (HL), second language (L2), and third language (L3) learners who wrote and revised three short essays and received a different type of WCF for each essay (i.e., direct, coding, or underlining). Comparison of pre- and post-feedback texts and analysis of think-alouds served as the basis for determining whether one type of feedback promoted higher depth of processing (DoP) and whether this processing was mediated by error type and language background. The findings indicate that feedback type did interact with DoP, and that this interaction was in some ways mediated by learner background and error type. This research serves as a first step toward understanding how these three learner groups are impacted by these commonly used feedback types and is therefore important to drive evidence-based pedagogical decisions.
The role of cognitive individual differences in digital versus pen-and-paper writing
Authors: Vasylets Olena , Mellado M. Dolores , Plonsky Luke
Published: December 2022

It is unknown whether and to what extent cognitive individual differences may play different roles in paper versus computer-based second language (L2) writing. This exploratory study is a first attempt to explore this issue, focusing on the effects of working memory and language aptitude on the quality of paper versus computer-based L2 writing performance. Forty-two Spanish learners of L2 English performed a problem-solving task either digitally or on paper, took a working memory n-back test, and completed LLAMA tests to measure language aptitude. The quality of their L2 written texts was assessed in terms of complexity, accuracy and fluency (CAF) measures. The results indicated that the role of cognitive individual differences may vary depending on the writing environment.
Псалтирь царя Давида Симеона Полоцкого в контексте паралитургической и парафрастической традиции XVI–XVII вв.
Authors: Niekraszewicz-Karotkaja Żanna
Published: December 2022

The collection of poetic translations of King David’s Psalms, compiled by Symeon of Polatsk, is usually used in the scientific discourse under the descriptive title Psaltir’ rifmotvornaya. In this article, King David’s Psalter (1680) of Symeon is considered not in the context of the poet’s entire creative heritage, but in terms of the evolution of the European book tradition of paraliturgical discursive psalmic practices and the poetic paraphrase of the psalms, beginning with the German poets of the Renaissance Helius Eobanus Hessus and Ioannes Mylius Libenrodensis. Not only the artistic experience of Western and Central Europe but also of the Grand Duchy of Lithuania is taken into account. Addressing the broader historical context allows us to move away from traditional scientific discussions about the degree of influence of Jan Kochanowski’s poetic paraphrases of psalms (Psałterz Dawidów, 1578) and to more adequately appreciate Symeon’s merits in the field of cultural transfer. The King David’s Psalter of Symeon is evaluated as a result of the interaction of the European book tradition of creating poetic paraphrases of biblical texts and the East Slavic singing culture. The functioning of this culture from the end of the 16th century and especially in the 17th century was greatly influenced by Polish spiritual songs (first of all, the poetic paraphrases of the psalms of Jan Kochanowski), as well as by the increased interest in polyphonic singing thanks to Nikolai Diletsky.
На пути к оптимальному структурированию системы видовых парадигм в русском языке
Authors: Klimonov Vladimir
Published: December 2022

The author of this paper defines the aspectual paradigms of Russian verbs as such grammatical structures whose formal aspect is correlated with the conceptual one, therefore being its cognitive counterpart. With a view to analysing these paradigms he uses the theory of markedness as an analytic tool. According to it, the grammatical changes that occur in natural languages originate from general principles of naturalness which are typologically relevant. They result in morphological shifts that are linked to the verbalisation of Russian aspectual paradigms and allow to predict the direction of their development. In particular, the principle of natural grammatical development should be considered crucial. It means that the grammatical changes in natural languages cause elimination of marked elements, so that these more complex linguistic structues are replaced with less complex ones. Such a principle manifests an unconscious desire of language users to minimise their linguistic efforts, as it would place an additional burden on interpersonal communication.
Digital Curation and Contemporary Documentary Filmmaking
Authors: Barnes Heather L.
Published: December 2022

Documentary films have evolved considerably since 1922s Nanook of the North. Fans of nonfiction now stream multi-episode documentaries on platforms like Netflix or catch a feature at one of many documentary-centered film festivals around the world. Inexpensive video cameras and internet distribution have expanded the documentary film universe exponentially. From 1-min films to feature-length theater releases, moviegoers around the world have embraced this diverse and growing genre. To the benefit of aspiring filmmakers, documentaries can now be filmed on a wide array of digital video devices, including smartphones, and edited inexpensively. Given this abundance, it may seem counterintuitive that, from a preservation perspective, the documentary film genre faces substantial risks. Research indicates that independent filmmakers lack access to resources that would ensure the long-term stewardship of their works (Academy of Motion Picture Arts and Sciences 2012). This research project examines documentary film production through the lens of digital curation. It describes filmmakers’ data practices and proposes a data curation model designed to guide filmmakers and film archives in developing data management plans similar to those currently used by researchers in the sciences. The proposed data curation model reflects the influence of the growing research data management field and integrates components related to digital storage, copyright, publishing, context, and file organization.
Identification and distribution of leatherjackets (Tipula spp.) in the Republic of Ireland
Authors: Moffat A. , Gaffney M. T. , Brennan F. , Cole L. , Jackson G. , Konkolewska A. , McNamara L.
Published: December 2022

The soil-dwelling larval stage of crane flies, commonly known as leatherjackets, are classified as agricultural pests in Europe, and pests of turf in North America and Canada. They cause significant damage and yield loss in many cropping systems through their feeding on plant roots and stems at ground level. The effective chemical control for these pests, chlorpyrifos (available since 1965), was prohibited across Europe in 2019. This has left severely restricted control options for growers. Unlike Northern Ireland and Great Britain, no leatherjacket surveys or routine identifications have been conducted across Ireland. Therefore, the leatherjacket species of agronomic importance has not been confirmed. Since lifecycles, feeding behaviour and damage periods differ between species, identifying the most common species is a vital first step in any pest management strategy. Here we report key findings from a 2-yr structured survey of Irish crops, conducted in 2019 and 2021, where 135 sites were sampled. Both grassland and cereal crops were inspected. Soil cores and soil samples were collected and larval abundance determined. The European crane fly, Tipula paludosa Meigen, accounted for approximately 70% of larvae collected and identified (n = 337). In 2019, 40% of grasslands exceeded the threshold of 1 million larvae/ha, while only 3.3% of cereal fields were over the threshold of 600,000 larvae/ha. These results indicate that agricultural grasslands in Ireland have the potential to be significantly impacted by leatherjacket damage, although this may vary temporally and geographically across the island. Without effective control options, yield losses will be highly probable.
Global Infectious Diseases in November 2022: Monthly Analysis
Authors: Zou Jiazhen , He Shiping , Yu Wenjin , Li Guodan , Li Taihan , Xiang Qi , Liu Dongliang , Luo Yi , Sun Yinfu , He Minjing , Zhang Shuqiong , Su Qun , Gu Dayong
Published: December 2022

Infectious diseases, such as COVID-19 and monkeypox, pose a severe threat to economic development in all countries, as well as to the health of people everywhere. The World Health Organization and National Health Council epidemiological websites were used herein as data sources. Shusi Tech’s Global Epidemic Information Monitoring System was used to analyze the data for infectious diseases, determine changes in global epidemics, determine the distribution and quantity of infectious disease cases from October 24, 2022 to November 23, 2022, and analyze their changing trends. Furthermore, the analysis of these data can be used to predict prevalence rates, and assess epidemic prevention and control measures.
Associations Of Fatty Acid Composition In Leukocyte Membranes With Systemic Inflammation In Chronic Obstructive Pulmonary Disease Progression
Authors: Denisenko Yulia K. , Novgorodtseva Tatyana P. , Vitkina Tatyana I. , Knyshova Vera V. , Antonyuk Marina V. , Bocharova Nataliya V. , Kytikova Oxana Yu.
Published: December 2022

Background — The development of systemic inflammation is a key pathogenetic mechanism in progression of chronic obstructive pulmonary disease (COPD). Fatty acids (FAs) and their oxidized derivatives serve as essential regulators of inflammation. The relationship between systemic inflammation and FA metabolism in COPD is poorly understood. In our research, we focused on examining the FA composition of the leukocyte membrane in COPD and the FA metabolism in association with systemic inflammation. Objective — We examined 137 patients with mild, moderate, or severe COPD. The control group comprised 32 healthy non-smokers. Methods — Blood cytokines and immune cell subpopulations were evaluated by flow cytometry. The FA composition of the leukocyte membranes was analyzed by gas chromatography. The concentrations of eicosanoids (thromboxane B2 (TXB2), leukotriene B4 (LTB4)) in plasma were measured by ELISA. Results — Our results implied systemic inflammation in all patients with COPD. The analysis of the FA composition of leukocyte membrane demonstrated increased level of saturated FAs and n-6 polyunsaturated fatty acids (PUFAs), along with reduced levels of monounsaturated FAs and n-3 PUFAs, in patients with COPD. The TXB2 and LTB4 content was increasing in COPD patients. We established a significant correlation with n-6 PUFAs, immune cells, and cytokines, which was indicative of an important role of FAs in the progress of systemic inflammation in COPD. Conclusion — Thus, FA modification of immune cells in patients with chronic pathologies of the bronchopulmonary system leads not only to disruption of the cell membrane structure, but also to the pathology of immune response regulation, and contributes to the development of the inflammatory process. The latter is a decisive factor in the pathogenesis of COPD.
Characterizing The State Of Heart Rate Autonomic Regulation And EEG In Elderly Women With Falls Syndrome
Authors: Shiryaeva Taisiya P. , Fedotov Denis M. , Gribanov Anatoliy V. , Deryabina Irina N. , Krainova Irina N. , Bagretsov Sergey F.
Published: December 2022

Objective — The goal of our study was to evaluate the contribution of the central and autonomic nervous systems to the maintenance of postural balance in the elderly. Material and Methods ― This study included 120 healthy women 60-74 YO living in the community. They were distributed among two subgroups: (1) fallers (n=60) and (2) non-fallers (n=60). Fallers had falls in the past 12 months, while non-fallers had none. Walk tests were performed using Balance Master® posturography machine (NeuroCom, Natus, USA). The state of the central nervous system was assessed by Geodesic 300 EEG system (GSN; Electrical Geodesics, Inc.; Eugene, OR, USA). The state of the autonomic nervous system was assessed by the VNS-Spectrum (Neurosoft, Russia) via cardiointervalography. Results ― In Sit to Stand test, the postural sway velocity was higher (p=0.047) and the walking speed (p=0.008) in Tandem Walk test was lower in fallers, compared with non-fallers. The results of the Step Quick Turn test showed that the movement times of the left and right legs were longer for the fallers vs. non-fallers (p=0.044 and p=0.036, respectively), and postural sway values during turning left or right were higher in fallers as well (p=0.001 and p=0.003, correspondingly). At the same time, Step Up and Over test revealed that lift-up index values were higher in fallers vs. non-fallers (p=0.016). There were no statistically significant differences between the groups in the state of the autonomic nervous system. The absolute spectral power of the EEG was lower in the frontal region of the right hemisphere in the alpha and beta EEG bands in the study group, compared with the control. Conclusion ― A deterioration in the quality of performing complex motor actions and a decrease in postural control in elderly women with falls syndrome were which may have caused their postural instability. Our results confirmed the need for early assessment of the dynamic components of postural control to prevent the development of falls as a geriatric syndrome.
Carbohydrate Metabolism, Pancreas Functional Activity And Diet In Young Residents Of Two Ethnic Groups In The North
Authors: Averyanova Inessa V.
Published: December 2022

The objective of this study was to analyze the type and balance of the diet, examine the hormonal regulation of carbohydrate metabolism in order to identify the etiology of hyperglycemic manifestations in young people of two ethnic groups residing in the territory of Magadan Oblast. Methods — Blood serum carbohydrate parameters were measured using the ion-exchange chromatography, enzymatically enhanced chemiluminescence, and the hexokinase method. Results — We established that the homeostatic model assessment of insulin resistance (HOMA-IR) index did not exceed the reference limits, which implied that the examined young men of two ethnic groups had no insulin resistance. The indigenous subjects demonstrated statistically significantly higher values of glycosylated hemoglobin, closely approaching the upper limit of the reference range. The blood insulin level in examined young men was lowered towards the lower limit of the reference range. Against the background of detected hyperglycemic manifestations in young men of two studied groups in Magadan Oblast, their dietary intake was characterized by insufficiency and imbalance in both micronutrient and macronutrient compositions. It was established that the observed diet contained an excessive amount of mono- and disaccharides in 49% of Caucasians and 72% of natives, which was 52% and 108% higher, respectively, compared with the reference range against the pronounced deficiency of chromium, copper, and vitamin D. Conclusion — The results indicated an unbalanced diet with excessive intake of mono- and disaccharides, along with reduced insulin secretion and increased glycosylated hemoglobin, which was more pronounced in the indigenous group, probably causing hyperglycemic manifestations in the carbohydrate metabolism observed in young residents of Magadan Oblast.
Parameters Of Myocardial Electrical Instability In Patients After Myocardial Infarction Comorbid With A Novel Coronavirus Infection (COVID-19)
Authors: Tonkoglaz Anastasia A. , Averyanova Elena V. , Barmenkova Yulia A. , Yangurazova Maryam A. , Lukyanova Marina V. , Oleynikov Valentin E.
Published: December 2022

Objective — This article aims to assess parameters of myocardial electrical instability and arrhythmic events in patients after myocardial infarction (MI), with and without ST-segment elevation, comorbid/noncomorbid with a novel coronavirus infection (COVID-19) using a long-term electrocardiographic (ECG) monitoring. Methods — The study included 64 subjects: 25 (39%) patients with MI comorbid with COVID-19 (MI+C group) and 39 (61%) patients with MI noncomorbid with a novel coronavirus infection (MI group). The mean age of patients was 54.3±6.8 years. A long-term ECG monitoring for 97.4 (95% CI 77.9-115.2) hours was performed with Astrocard®-Telemetry system (Meditek JSC, Russia), starting from the 4th day of MI. Rhythm and conduction disorders, along with ischemic episodes were recorded; an analysis of ventricular late potentials, heart rate turbulence, and QT dispersion was carried out. Results — There were no differences in the frequency of delayed afterdepolarizations in MI and MI+C groups: 15-28% and 18-33% of patients, respectively. An analysis of turbulence parameters did not reveal statistically significant differences between the groups. Such arrhythmic events as frequent supraventricular extrasystole and life-threatening arrhythmias (ventricular extrasystole of grade 4A and higher sensu B. Lown and M. Wolf) were recorded significantly more often in the MI+C group than in the MI group: 48% vs. 20.5% (p=0.021) and 24% vs. 5.1% (p=0.026), respectively. Conclusion — The novel coronavirus infection (COVID-19) exacerbates myocardial electrophysiological heterogeneity in the acute cardiovascular event and is associated with an increase in clinically significant arrhythmic events.
Interaction Of Inflammatory Parameters And Thiol/Disulfide System Of Antioxidant Protection In Chronic Obstructive Pulmonary Disease
Authors: Vitkina Tatyana I. , Mineeva Elena E. , Sidletskaya Karolina A.
Published: December 2022

Introduction — Increased incidence and prevalence of chronic obstructive pulmonary disease (COPD) provides rationale for describing the disease progression mechanism, considering the interaction of key participants of this process. The objective of our study was to establish the dysfunction parameters of thiol/disulfide system components and adaptive immunity unit in patients with stable chronic obstructive pulmonary disease (COPD). Material and Methods — We examined patients with stable COPD of moderate (62 subjects) or severe (50 subjects) grades. The control group included 32 subjects. Prooxidant and antioxidant markers of oxidative stress were investigated with ELISA. We determined cytokine levels in blood plasma and the number of T helper cells expressing IL-6R with flow cytometry (BD FACSCanto II, USA). Correlation pleiads sensu Terentiev were employed to visualize the data. Results — Changes in both antioxidant and cytokine status of subjects with COPD of varying severity grades implied the progression of systemic inflammation in conditions of uncontrolled activation of adaptive immunity unit rather than just a shift in the peroxide balance and an increase in oxygen metabolites. Conclusion — Accumulation of biomolecule peroxidation products, imbalance in the prooxidant-antioxidant system, and a change in pathogenetic mechanism of inflammation could lead to an aggravated course of bronchopulmonary pathology.
Difficulties Of Enterobacteriaceae Genome Annotation In Deciphering Gastrointestinal Microbiome Datasets Obtained By 16S RRNA Gene Amplicon Sequencing
Authors: Klimenko Elizaveta S. , Belkova Natalya L. , Pogodina Anna V. , Rychkova Lubov V. , Darenskaya Marina A.
Published: December 2022

Sequencing of the 16S rRNA gene amplicon is the cornerstone of the method for studying diverse bacteria in complex microbial communities. However, its use is complicated by an error rate of 10–17% when annotating 16S rRNA gene sequences. In our study, we examined the degree of accuracy of the taxonomic database of Enterobacteriaceae, compiled using the SILVA 132 reference database and a previously obtained dataset, viz. the microbiome of the gastrointestinal tract in adolescents with normal body weight and obesity. Material and Methods — In this study, previously obtained 16S rRNA gene amplicon sequencing data were used, and the deciphering was carried out using the QIIME2 2019.4 platform. Phylogenetic analysis was performed using MEGA X software. Results — Phylogenetic analysis of this family based on the studied V3–V4 fragment was hampered by polyphyly among some genera, and for half of the variants of the amplicon sequences it was not possible to clarify their genus. Statistical analysis did not reveal significant differences between the samples. Conclusion — Although the average values of bacterial genera in the studied groups intuitively differed from each other, statistical analysis did not reveal significant differences between the samples. However, it can be assumed that a more detailed study of taxonomic diversity, taking into account factors, such as enterotype, duration of breastfeeding and family history, may reveal differences in the frequency distribution.
Direkt Kompozit Rezin Restorasyonla Estetik Kaygının Giderilmesi, 36 Aylık Takip
Authors: TUNCDEMIR Makbule Tuğba , ELMACI İrem
Published: December 2022

Son yıllarda koruyucu ve estetik restoratif diş hekimliğindeki gelişmelerle bugüne kadar çoğunlukla protetik uygulamalarla giderilen yapı, şekil ve renk bozuklukları adeziv teknikler ile tek seansta tedavi edilebilmektedir. Özellikle adeziv sistemler ve kompozit rezinlerdeki gelişmelerle daha konservatif, ekonomik bir yaklaşımla ve protetik işlemlere kıyasla çok daha kısa sürede estetik kaygılar giderilebilmektedir. Direkt kompozit rezinler doğru teknikle uygulandıklarında tatmin edici estetik sonuçlar alınabilmektedir. Bu olguda, 22 numaralı dişin restorasyonunun kaybı üzerine kliniğimize başvuran hastaya nanohibrit kompozit rezin (Sirona Ceram.x ,Dentsply) ile tek seansta direkt kompozit rezin restorasyon uygulanmıştır. Hastanın 18. ve 36. ay takipleri yapılmış ve değerlendirilmiştir.
Renklenmiş Kök Kanal Tedavili Maksiller Santral Dişin Beyazlatma Tedavisi ve Estetik Rehabilitasyonu: Olgu Sunumu
Authors: TÜZEL Seden , ÜÇTAŞLI Mine Betül
Published: December 2022

Dişlerdeki renk değişimleri, lokalizasyona (eksternal ve internal faktörler gibi) ve etiyololojiye dayanan çok faktörlü olgulardır. Hangi tip beyazlatma tedavisine ihtiyacımız olduğuna karar vermek en önemli durumdur. Kök kanal tedavisi uygulanmış dişlerdeki renk değişikliklerinin nedenleri arasında pulpa dokusu artıkları, kanal dolgu patları, irrigasyon ve pansuman materyalleri yer almaktadır. İntrakoronal beyazlatma tedavisi, devital dişlerin beyazlatılmasında etkili ve minimal invaziv bir yaklaşımdır.

Bu vaka raporunun amacı renklenmiş kök kanal tedavili sol maksiller santral kesici dişin beyazlatılması ve hastaya estetik restorasyonların sunulmasıdır.
Polidiastemanın silikon anahtar kullanılarak direkt kompo-zit rezin veneerler ile rehabilitasyonu: olgu sunumu
Authors: BALABAN Sena , KARAKAŞ Mert , ARISU Hacer Deniz
Published: December 2022

Diastema, diş boyutları arasındaki farklılıklar, ark ve diş boyut uyumsuzlukları, diş eksiklikleri gibi sebeplerle dişler arasında oluşmuş boşluklara verilen addır. Birden fazla boşluğun olduğu durumlar ise ‘’polidiastema’’ olarak adlandırılır. Üst çene ante-rior dişleri arasındaki boşluklardan kaynaklanan estetik kaygı-ları nedeni ile kliniğimize başvuran 40 yaşındaki kadın hasta-nın intraoral muayenesinde hastanın 13-23 numaralı dişleri ara-sında diastema varlığı tespit edildi. Hastanın periodontal sağlı-ğı ve oral hijyen farkındalığı yüksek seviyedeydi. Tedavi seçe-nekleri detaylı şekilde anlatıldı. Konservatif, düşük maliyetli, pratik olması sebebiyle ve hasta isteği doğrultusunda, kompozit rezin veneerler ile tedavi yapılmasına karar verildi. Birden faz-la diastema varlığı sebebiyle tedavi silikon anahtar ile yapıldı. Restorasyonlar hastanın estetik beklentilerini karşıladı. Uzun vadede klinik başarı elde etmek için hastaya oral hijyenini op-timum seviyede tutması ve restorasyonun renk stabilitesi için kromojenik yiyecek içecek tüketiminden kaçınması gerektiği hastaya anlatıldı. Restorasyonların düzenli kontrolü için takip randevuları verildi.