bluuebunny/crossref_metadata_2025 huggingface dataset:
Julia Ledóchowska wobec Aktu 5 XI 1916 r.
Authors: Witkowski Stanisław
Published: November 2020

Celem artykułu jest ukazanie działalności matki Urszuli (Julii) Ledóchowskiej w sztokholmskim Komitecie Polskim Pośredniczącym (Polska förmedlingskommitten), powołanym w połowie marca 1916 r. w momencie ogłoszenia Aktu 5 listopada 1916 r., oraz reakcji szwedzkiej Polonii na ten wydany w imieniu cesarzy Niemiec i Austro-Węgier manifest, głoszący powołanie niepodległego Królestwa Polskiego. Autor przedstawia wachlarz nastrojów wśród polonijnych działaczy w Sztohkolmie oraz tamtejszych polityków z racji możliwego odrodzenia Polski, z czołową rolą matki Ledóchowskiej, wiceprezes Komitetu Polskiego w Sztokholmie. Przedstawione zostały artykuły ukazujące się w szwedzkiej prasie, obrazujące oddźwięk szwedzkich i polonijnych środowisk wobec nowej polityki państw centralnych: będące wynikiem działań propagandowych, mających pozyskać przychylność opinii publicznej wobec nowej polityki państw centralnych, dotyczące rozważania na temat jej spodziewanych pozytywnych i negatywnych skutków, jak też przyszłego losu Polski. Autor opisuje również obawy przed utworzeniem armii polskiej z ramienia państw centralnych. W artykule wykorzystane zostały przede wszystkim raporty delegata Departamentu Wojskowego Naczelnego Komitetu Narodowego w Sztokholmie Stanisława Wędkiewicza do centrali w Krakowie, a także listy matki Urszuli Ledóchowskiej, której opinia miała duże znaczenie dla sposobu postrzegania Aktu 5 listopada przez szwedzką Polonię.
Prediction of Farmers’ Access to Pradhan Mantri Fasal Bima Yojana (PMFBY) Scheme using Discriminant Analysis
Authors: Santhi P. , Sangeetha S.
Published: November 2020

Crops are subject to risks generated by adverse weather conditions, natural disasters, biological reasons and market price volatility. Crop insurance is a strategy hedge the risk of loss arising out of agricultural activities. The PMFBY was launched in 2016 with an impetus on agricultural sector. The successes of crop insurance business depend on the awareness of the beneficiaries about the products and services rendered. Hence the study aims at analysing awareness and access to the Scheme by the farmers who have insured their crops mandatorily or voluntarily. The sample farmers were drawn from Thondamuthur block in Coimbatore District of Tamil Nadu, which is notified by PMFBY scheme as the Low Risk Profile District purposively taking into account those who have insured their crops under PMFBY Scheme during the study period of Kharif 2018. The sample size includes 187 respondents comprising of 115 loanee farmers covered under the scheme and 72 non-loanee farmers covered under the scheme voluntarily. The primary data were collected through structured interview schedule and were subjected to test of reliability. The secondary data was collected from published sources. The descriptive statistics and inferential statistics namely factor analysis and discriminant analysis was employed in data analysis. The result showed that a moderate level of awareness is prevailing PMFBY scheme among the farmers about the features of the scheme. The non-loanee farmers were much aware of various features than loanee farmers. The access to the scheme by the non-loanee farmers were determined by announcement of cut-off date ahead of the particular season and support services available at the villages. The access to the scheme by the loanee farmers is because of mandatory deduction of premium out of agricultural credit, Insurance policy provided at their doorstep by authorities, agencies and involvement of local leaders.
Editorial
Authors: Venkatraja B.
Published: November 2020

No Abstract.
Back to the Future?
Authors: Schouwenburg Hans
Published: November 2020

The study of history currently witnesses two markedly different material
turns. Some historians are using material artefacts as alternatives to
textual sources. Others draw on ‘new materialism’, a new tradition in
thought that originated in the field of gender studies. Both groups are
trying to move beyond the cultural turn, which has dominated the study of
history since the 1980s. However, the first group merely extends the
programme of the cultural turn into new domains without rejecting its
methods or epistemological foundations. The latter group, on the other hand,
provides a new cultural theory. This article demonstrates that the ‘new’ in
new materialism is not so much an increased engagement with the material
world, but rather a new conceptualization of
developing theory and reading texts, which cuts through established
dichotomies between matter and meaning or culture and the social. In doing
so, a new materialist history can solve some of the problems associated with
the cultural turn and the turn to material artefacts.
Formations of European Modernity
Authors: Pasture Patrick
Published: November 2020

In Formations of European Modernity, Gerard
Delanty, one of the foremost social theoreticians of Europe, offers a
historical-sociological assessment of the idea of Europe as the development
of modernity from a cosmopolitan perspective. With this book, based upon a
broad and impressive discussion of sociological and historical literature,
Delanty somewhat comes back from his earlier constructivist approach in
favour of a theory that emphasizes the originality of Europe and assesses
European history as the development of modernity, interpreted in a classical
neo- Weberian sense. This approach sits uneasily with his ambition to
present a cosmopolitan view on Europe, which emphasizes the interactions of
Europe with the rest of the world, all the more so as he largely ignores the
postcolonial critiques of Eurocentric narratives as well as modernization
theories. While Delanty is still quite successful in his assessment of
historical diversities in Europe, Formations of European
Modernity nevertheless disappoints. While the focus on
global interactions is highly commendable, the lack of critical assessment
and contextualization leads to a neglect of the fact that Europe often
despised the (contribution of the) other. Hence his presentation of
cosmopolitan Europe is flawed, and remains if not Eurocentric at least
overly Europhile.
C-C motif chemokine ligand 5 and C-C chemokine receptor type 5: possible diagnostic application in breast cancer patients
Authors: Dąbrowska Emilia , Przylipiak Andrzej , Zajkowska Monika , Piskór Barbara Maria , Borowik-Zaręba Aleksandra , Ławicki Sławomir
Published: November 2020

The chemokine CCL5 and its receptor CCR5 play important roles in cancer invasion and metastasis. Based on our knowledge, our results were the first that presented the diagnostic usefulness of CCL5 and CCR5 in breast cancer (BC) patients, based on receiver operating characteristic (ROC) curve analysis. We wished to examine further if CCL5 and CCR5 are appropriate to be applied as BC markers for early screening. Values of tested parameters in patients’ plasma were determined by CMIA method (Chemiluminescent Microparticle Immunoassay, CA 15-3) as well as by ELISA method (Enzyme-Linked Immunosorbent Assay, CCL5 and CCR5). Levels of CCL5 in the plasma were markedly increased, while those of CCR5 were remarkably lower in BC patients when compared to the control groups. Moreover, higher levels of CCL5 in BC corresponded to advanced tumor stage, while the levels of CCR5 decreased with increasing the disease stage. CCL5 concentration was characterized by high sensitivity (SE) (68.04%) and high specificity (SP) (100.00%) in the BC patients. Results indicated that area under the curve (AUC) corresponding to CCL5 (0.8116) had a higher value than this corresponding to CA 15-3. The AUC value of CCL5 was significantly increased in the early phase of BC (stage I – 0.7089; stage II – 0.8313). The maximum range in the BC patients was observed for the combined analysis of the tested measurands with CA 15-3 (0.8335). In conclusion, our research indicates that examination of plasma CCL5 and CCR5 may be useful in BC diagnosis at the early stage of the disorder, especially when combined with CA 15-3.
Dimensões da qualidade de vida no trabalho: representações de equipes de enfermagem em ambiente hospitalar
Authors: Viana Viviane Aparecida , Querino Rosimár Alves , Aragão Ailton De Souza
Published: November 2020

Esta é uma pesquisa qualitativa realizada em um hospital público federal do interior de Minas Gerais em 2017, com o objetivo de analisar as representações de equipes de enfermagem de um hospital federal de ensino acerca das dimensões constituintes da qualidade de vida no trabalho. Utilizou-se questionário sociodemográfico e entrevista com teste de evocação semiestruturado. Na exploração e análise de dados foram empregadas a estatística descritiva e análise de conteúdo. Pesquisou-se 45 trabalhadores de enfermagem, na sua maioria mulheres – enfermeiros (17,8%), técnicos de enfermagem (57,8%) e auxiliares de enfermagem (24,4%). Os participantes explicitaram conhecer ações voltadas à qualidade de vida no trabalho e destacaram a busca individual e em contextos externos para cuidar de sua saúde. O paradoxo que se coloca aos trabalhadores em geral, e às equipes de Enfermagem hospitalar em particular, reside na representação de que o trabalho pode produzir adoecimento e sofrimento, o que se constitui em importante espaço para a atuação da saúde do trabalhador.
The Improvement of Scientific Approaches to Bases for Classification of Civil Procedure Law Principles
Authors:   Postgraduate Student of the Department of Civil Law and Procedure of the Vyatka State University, Klabukov Ivan S.
Published: November 2020

Аmong the current unsolved problems of the science of civil procedure law is the question of finding optimal criteria for classifying the principles of civil procedure law. The need to study this issue is due to the fact that in the science of civil procedure law, the most developed classical bases for the classification of principles. At the same time, law enforcement practice shows that participation in civil proceedings of public authorities and local self-government bodies modifies the essence of sectoral principles of civil procedure law. In this regard, the author gives a critical analysis of the principles of civil procedure law based on the existing legal literature and justifies the need to introduce a new criterion for the classification of principles, taking into account the participation of a special subject of civil procedural relations — a state authority or a local self-government body.
Inner Conviction of a Judge and Objective Standards of Proof: Integral Elements of the Single System? (the final part)
Authors:   Postgraduate Student of the Law Faculty of the National Research University Higher School of Economics (NRU HSE) LL.M., Yaltsev Aleksandr A.
Published: November 2020

This paper presents theoretical analysis of the fundamental possibility of introduction the standards of proof institution in the assessment of evidence model of Romano-German legal family countries.
Polling Students as an Integral Element of Objective Assessment of the Quality of the Educational Process in a Higher Educational Institution
Authors:   Assistant Professor of the Department of Legal Culture and Human Right Protection of the North Caucasian Federal University, Candidate of Legal Sciences, Assistant Professor, Vorotilina Tatyana V.
Published: November 2020

Purpose. The relevance of the scientific appeal to the problems of the quality of education in general and higher education in particular is essential for all subjects of the educational process. The final result and the achievement of the goals of education directly depend on the expansion of the criteria and approaches to an objective assessment of the quality of the teacher’s activity, and, in consequence, to improving his educational and methodological component of his work. The novelty of the study lies in the analysis of the quality of the educational process taking into account the views of students as direct participants in this process. Methods: the methodological basis of research is the dialectical method of cognition of reality, as well as a set of general scientific and private scientific methods of cognition; especially widely is used the methodology of specific social legal studies (observation, questionnaires, analysis of written sources, and methods of summarizing information, etc.). Results. The results of the research showed that the questioning of students is a necessary structural element of objective assessment system of education’s quality in the university, which should be used with a certain frequency, improving the survey methodology and respecting the moral and ethical standards in selecting indicators and scoring. Monitoring the quality of higher education through questioning students requires a scientific approach and generally affects the effectiveness of education. Scientific and practical significance. Conclusions can be used to create and upgrade local normative acts of higher education institutions, as well as conducting comprehensive studies of the quality of higher legal education and ways of its increase.
The exosomes role in pathogenesis of cardiovascular diseases
Authors: Schava S. P. , Stepanov E. V. , Sorokin V. A.
Published: November 2020

According to World Health Organization, annually cardiovascular diseases cause 17,5 billion deaths in the developed world. This is the reason why the study of molecular mechanisms of these pathologies has a huge importance for the development of new diagnostic and therapeutic strategies. One of the strategies on this matter is the research of the small extracellular vesicles or exosomes and its role in pathogenesis of cardiovascular diseases. Exploring their transporting and signaling functions in the development of acute coronary syndrome, stable angina, heart valve diseases, hypertrophic cardiomyopathy, vascular atherosclerosis has a great importance.

Exosomes are spherical vesicles of 30–100 nm, expressed by almost all human cells. Their cytoplasmic membrane has lipid bilayer structure with tetraspanins CD9, CD63, CD81 and CD82 as the markers. Exosomes act as effectors transferring microRNA, mRNA, cytokines and growth factors between varies cells.

The aim of this review is to analyze the literature data of exosomal role in the development of main cardiologic syndrome’s and evaluation of existed literature on exosomes potential as therapeutic target.
Modern robotics in medicine
Authors: Mosoyan M. S. , Fedorov D. A.
Published: November 2020

Today, robot-assisted surgery and the use of robots in medicine marks a qualitatively new stage in the development of minimally invasive technologies and endovideosurgery, due to the high level of accuracy, functionality and ergonomics of modern robotic systems. With the help of robotic technologies, the quality of diagnostic manipulations as well as the results of therapeutic procedures and surgical interventions are significantly improved, which ultimately leads to an improved prognosis and quality of life for patients, while also expanding the capabilities of clinicians. This review article presents the main historical milestones and prerequisites for the development of automation and robotic technologies used in various industries, from ancient times to the present. The history of the use of robotic procedures in various fields of medicine is briefly described. Special attention is paid to robot-assisted surgery as one of the main bases for applying modern technologies. At the moment, we can safely say that medical robotics plays a very important role in the development of surgery of the future.
Negotiations, expropriation and compensation for establishing cemeteries in Poland an overview of the subject matter
Authors: Lis Piotr
Published: November 2020

The subject matter of this work is the functioning of a specific market of undeveloped real estate intended for cemeteries. There is a need in Poland not only to expand the existing cemeteries but also to establish new ones. However, such investments are successfully made only in a few gminas, not to mention big cities, where they seem even harder to be carried out. The aim of this article is to outline the issues of negotiations, expropriation and compensation in the process of investment implementation in Poland. In the negotiation process between a gmina (commune) and a private entity, carried out for the purchase of land intended for cemeteries, it has been proved that the gmina must assume the cost of the investment at approximately 55% of the purchase price of land intended for single-family housing on a given local market. Additionally, the author indicates the limitations associated with the location of investments in local spatial development plans as well as the limitations in terms of conducting effective negotiations for purchasing land intended for cemeteries by means of an agreement. The main problem indicated in the work is the location damage (suffered or not), which has largely contributed to blocking the contractual purchase of land and substantially complicates and delays termination of the expropriation procedure.
Cmentarz w strukturze przestrzennej miasta
Authors: Klima Ewa , Wycichowska Barbara , Popek Weronika
Published: November 2020

Umieranie nie mieści się we współczesnej globalnej kulturze pop gloryfikującej młodość i witalność. Jeśli dodać do tego katolickie sacrum-tabu śmierci okaże się, że dzisiaj nie ma miejsca na cmentarze. Celem artykułu jest pokazanie, że nie da się ich jednak wyprzeć, że są częścią każdej cywilizacji i mają lokalizację w przestrzeni i krajobrazie. Ważnym spostrzeżeniem jest to, że znaczenie i miejsce cmentarzy zmieniało się tak, jak zmieniała się kultura. Posłużono się przykładem Łodzi.
Computed Tomography and Anatomical Findings Encountered During Revision Endoscopic Sinus Surgery
Authors: Saberwal Akanksha Ajay , Velankar Haritosh , Dabholkar Yogesh , Shetty Adip K , Bhalekar Sharad , Shinde Devayani
Published: November 2020

Background and Objectives: Functional endoscopic sinus surgery (FESS) is a well-established strategy for the treatment of rhinosinusitis. However, some patients do not respond to primary surgery and may require revision surgery. Anatomic alterations due to prior sinus surgery, scarring and adhesions as well as associated chronic mucosal inflammation can make revision procedures challenging. In order to shed more light on the difficulties faced by surgeons performing revision FESS, a study was performed to identify areas of recurrent disease on computed tomography in patients undergoing revision surgery, as well as to evaluate intraoperative findings during revision FESS.Materials and Method: A hospital-based, interventional, non-randomized study was undertaken in 40 patients who underwent revision FESS. Multiple clinical parameters were recorded including number and type of previous surgeries, latest CT scans of the nose and paranasal sinuses, as well as intraoperative findings.Results: Our findings demonstrated the diffuse nature of mucosal disease on CT in our patient population. Fibrosis and adhesion formation were the most common intraoperative findings on revision sinus surgery along with residual air cells, polypoid mucosal regrowth, and middle meatal antrostomy stenosis.Conclusion: A careful evaluation of the patient is needed while contemplating revision surgery. A recent high-resolution CT scan is of paramount importance. The most common areas of disease recurrence are the ostiomeatal complex and residual ethmoids, and these areas should be given careful attention.
Assessment of Friedman Classification by Measuring Actual Tonsil Size During Surgery
Authors: Lee Jaeyoon , Yoo Soon Il , Lee Min Hyeong , Kim Do Hyun , Kim Sung Won
Published: November 2020

Background and Objectives: Adenotonsillar enlargement is a common cause of pediatric illnesses, including obstructive respiratory disease and recurrent airway infection. The current tonsil grading systems evaluate tonsil size, but the correlation with actual tonsillar size in a clinical setting has not been established.Materials and Method: Between May and July of 2018, we recruited 31 children who underwent adenotonsillectomy with no major craniofacial abnormalities. The actual size of the palatine tonsils, the long (L1) and short (S1) axes of the tonsil beyond the anterior pillar, and the real axes (L2 and S2) after tonsil extraction from the fossa were measured during surgery. Adenoid size was determined by measuring the adenoid-nasopharynx (AN) ratio through lateral view x-ray of the neck.Results: Though S1 was related to the Friedman scale (p<0.001), measured real axes were not (L2: p=0.058, S2: p=0.056). Also, adenoid size and AN ratio did not relate statistically to the Friedman scale (p=0.565). One of the measured real tonsil size parameters (S2) was related to AN ratio (p=0.048).Conclusion: For pediatric patients undergoing tonsillectomy and adenoidectomy, the Friedman grading scale based on physical examination may not reflect the actual size of the tonsils. Therefore, for children with obstructive sleep disorder or recurrent tonsillitis, intraoperative measurement of tonsil size can be helpful.
Violence and Discrimination against Women of Religious Minority Backgrounds in Pakistan
Authors: Tadros Mariz
Published: November 2020

The theme of this special collection of papers, the lived experiences of women who belong to religious minorities, has been a blind spot both in international development policy engagement and in much of the international scholarship on women, security and peace. Women who belong to religious minorities, who are socioeconomically excluded and are vulnerable to multiple sources of gender-based violence in Pakistan seem to have fallen through the cracks of the ‘leave no one behind’ agenda. The aim of this volume is to shed light on the day-to-day experiences of women and their families who belong to the Ahmadiyya, Christian, Hindu and Hazara Shia religious minorities in Pakistan. Each of the papers in this collection exposes the complexity of the intersections of gender, class and religious marginality in shaping the realities for women from these religious minorities.
Beyond Informal Social Protection – Personal Networks of Economic Support in Namibia
Authors: Oppel Annalena
Published: November 2020

This paper poses a different lens on informal social protection (ISP). ISP is generally understood as practices of livelihood support among individuals. While studies have explored the social dynamics of such, they rarely do so beyond the conceptual space of informalities and poverty. For instance, they discuss aspects of inclusion, incentives and disincentives, efficiency and adequacy. This provides important insights on whether and to what extent these practices provide livelihood support and for whom. However, doing so in part disregards the socio-political context within which support practices take place. This paper therefore introduces the lens of between-group inequality through the Black Tax narrative. It draws on unique mixed method data of 205 personal support networks of Namibian adults. The results show how understanding these practices beyond the lens of informal social protection can provide important insights on how economic inequality resonates in support relationships, which in turn can play a part in reproducing the inequalities to which they respond.
Rentabilidade e disclosure voluntário das empresas acionárias brasileiras
Authors: Rody Paulo Henrique Amaral , Sousa Anderson Fioresi , Souza Thiago Roozevelt , Reina Diane Rossi Maximiano
Published: November 2020

Este artigo verificou se a rentabilidade influencia de forma positiva o nível de disclosure voluntário das empresas. Para alcançar o objetivo deste artigo, foi adotado a técnica de Análise de Regressão Linear Múltipla com dados em painel de efeito fixo, de todas as empresas não financeiras da B3, sendo 527 empresas do período de 2010 a 2018 (nove anos), gerando uma amostra inicial total de 4.743 observações. Com base nos resultados do modelo econométrico, constatou-se que quanto maior for a rentabilidade, em média, menor será o nível de disclosure voluntário das empresas listadas na B3, evidência que contraria a hipótese da literatura, que sinaliza uma relação positiva da rentabilidade sobre o disclosure voluntário.
Lorenzo Delgado y Santiago M. Ló­pez (eds.). Ciencia en Transición. El lastre franquista ante el reto de la mo­dernización
Authors: Presas i Puig Albert
Published: November 2020

Este artículo reseña:  Lorenzo Delgado y Santiago M. Ló­pez (eds.). Ciencia en Transición. El lastre franquista ante el reto de la mo­dernización. Madrid: Sílex Ediciones, 2019, 386 pp.
TENSION AND EMOTIONALITY OF THE EDUCATIONAL ENVIRONMENT IN MODERN SCHOOL: RESEARCH RESULTS IN THE KRASNOYARSK REGION
Authors:   FSAEI HE «Siberian Federal University», Lukina Antonida K. , Setkova Irina N. ,   MAEI «Lyceum № 1», Sevostjanova Alina S. ,   FSAEI HE «Siberian Federal University»
Published: November 2020

The article discusses the materials of the sociological study of the educational environment of schools in the Krasnoyarsk region, conducted as part of the interregional research «Psychological comfort of education in modern rural school». Based on the theoretical analysis, the authors highlight two characteristics of the school environment, which have significant impact on the psychological health of schoolchildren and the success of education: tension and emotionality. The study found out quite serious differences in the assessment of the importance of educational parameters by different participants in the educational process: schoolchildren, parents and teachers. In general, all participants in the educational process highly appreciate the tension of the educational environment of schools; and there were no significant differences in the assessment of this parameter between rural and urban schools. According to the participants of the educational process, the school creates the necessary conditions for the development of different abilities of students, development of life skills. The emotional environment of the schools was also well received by all respondents. The most appreciated one is the potential for the development of educational activity, relationship with students, preservation of the personal dignity of students. However, many students note a high level of insecurity from the possible threat of insults, coercion to undesirable actions, from ill-will and insults from teachers and classmates. This requires the development of special measures to prevent bullying, improve the psychological culture of teachers, and design the educational environment of schools.
The Potential of Soy Isoflavones (Glycine max) and Magnetic Hydroxyapatite Nanoparticles as Osteoporosis Therapy for Menopausal Women
Authors: Ayik Rochyatul Jannah  , Faiza Rahma Ebnudesita  , Savira Butsainah Dienanta  , Reny I’tishom
Published: November 2020

Background: Menopausal women experience amenorrhea for 12 consecutive months. In Indonesia, one of four women aged 50 – 80 years has a risk of osteoporosis. This age range is related to the menopause phase. Low estrogen levels in menopausal women cause decreased bone mineral density resulting in osteoporosis. Osteoporosis is a degenerative disease characterized by decreased bone density and bone strength that causes fractures. This literature review aims to determine the potential of soy isoflavones (Glycine max) and magnetic hydroxyapatite nanoparticles as alternative therapies for osteoporosis in menopausal women.

Reviews: Soy isoflavones are phytoestrogens because they have estrogen-like structures and functions. Some studies explain that phytoestrogens have benefits in osteoporosis therapy by maintaining bone density through decreasing osteoclast resorption and stimulating osteoblasts. Consuming enough soy supplements everyday has been shown to increase bone mineral density. This effect is strengthened by coating the soy isoflavones with magnetic hydroxyapatite nanoparticles through two mechanisms, as a therapeutic agent and drug carrier. The magnetic field of the magnetic nanoparticles produces force and torque to increase the temperature until 42°C and trigger organelles movement, causing apoptosis of osteoclasts. Hydroxyapatite is a major component of bone mineral that replaces bone tissue deformity and has an osteoblastic effect in bone regeneration. Nano-sized hydroxyapatite will increase material properties and stability in high temperatures. However, hydroxyapatite has less magnetic activity so this function is completed by magnetic nanoparticles.

Summary: Therefore, the combination of soy isoflavones and magnetic hydroxyapatite nanoparticles works synergistically as an alternative therapy for osteoporosis in menopausal women.
Case Report : A Woman 27 Year Old with Mosaic Turner Syndrome Associate Hypogonadotropic Hypogonadism
Authors: Cennikon Pakpahan  , Bella Amanda  , Berliana Hamidah  , Rina Yudiwati
Published: November 2020

Background: Turner syndrome is a chromosomal abnormality found in phenotypically women who have one intact X chromosome and the absence of second sex chromosomes.

Case: The patient is a 27-year-old Javanese girl. At the age of 14 years, she came to the gynecology clinic with chief complaints of amenorrhea and then given cycloprogynova by the physcian, the complaint improved but menstruation did not appear in the following month did not return to the gynecologist  for evaluation. At the age of 26, she returned to the gynecologist and then was given medicine to stimulate menstruation and  was referred to an internist-endocrinologist because of  a suspected hypothyroid. Then a few months later the patient returned to the gynecologist and then examined hormones, ultrasound, and karyotyping for evaluation as well as establishing the diagnosis. FT4 hormone examination results 0.87 ng / dl, TSHs 0.708 Uiu / mL, T3 (Total) 0.49 ng / mL, FSH 2.38 Miu / mL, LH 1.3 Miu / mL, prolactin 14.7 ng / ml, progesterone <0.10 ng / ml, estradiol <5 ng / ml indicates hypogonadotropic hypogonadism with hypothyroidism. Ultrasound results showed hypoplasia with uterine axis measuring 2.27 x 2.09 cm. Karyotyping result with 45x / 46xx indicate mosaic turner syndrome. Patients were given progestin, esthero and also thyrax for hormone replacement therapy.

Discussion: Turner syndrome with hypogonadotropic hypgonadism is a rare variation of the turner syndrome. The definite cause is still uncertain. Some cases are usually accompanied by other hormone disorders such as thyroid and growth hormone.

Conclusion: A 27-year-old woman with hypgonadotrophic hypgonadism associated with mosaic turner syndrome. The diagnosis is done by history taking, hormone examination, imaging, and karyotyping. treatment given progestin, estrogen, and thyrax.
Peranan Faktor Usia Dalam Memoderasi Pengaruh Pemberian Insentif Terhadap Motivasi Kerja Karyawan Kantor Direksi PT. PG. Rajawali I Surabaya
Authors: Hermawan Hafiz , Sulasmi Siti
Published: November 2020

One of the company's efforts made in motivating employees is by giving rewards, such rewards are in the form of incentives. In order that these incentives can motivate employees, incentives given to companies can be either Monetary Incentive or Non-Monetary Incentives depending on how the appeal or the importance of the incentives for employees. But there are a few things to note companies, particularly with regard to the granting of incentives to boost employee motivation. Because in providing various forms of incentives to employees, the company needs to know the demographic characteristics of the employees as factors that can strengthen or weaken the relationship between incentives and employee motivation. One of the demographic characteristics of the form factor is the age of an employee, an employee who has a younger age it might be more motivated if the company gives incentives rather than a more senior employee. This is because a person's motivation in working for tend to be changed along with the increase of age. Employees with a younger age will likely pursue the monetary in the work, while employees who have senior will be more likely pursue the achievement of the monetary. Population and sample which became the object of this research is the 36 employees of  PT. PG. Rajawali I. The results of the study prove that Monetary Incentives and Non Monetary Incentives give significant effects either simultaneously or partial employee motivation of PT. PG. Rajawali I. Whereas the moderation effect of age factor is not significantly strengthen the impact of influence the granting of providing Monetary Incentives and Non Monetary Incentives of employee motivation PT. PG. Rajawali I.
Estresse e trabalho: o drama dos gestores de pessoas nas organizações contemporâneas
Authors: Fidelis Janaína Faria , Zille Luciano Pereira , De Rezende Fernanda Versiani
Published: November 2020

Objetivou analisar e descrever manifestações de estresse ocupacional em gestores de Gestão de Pessoas que atuam em empresas privadas em Minas Gerais. A pesquisa foi de natureza descritiva, envolvendo 170 gestores. Os resultados apontaram que 81,8% apresentaram manifestações de estresse, cujos sintomas prevalentes foram psíquicos, entre eles a ansiedade. Como fonte de tensão observou-se o contexto social, econômico e político ora em evidência no país e como indicador de impacto no trabalho, o desejo frequente de trocar de emprego. A estratégia de enfrentamento ao estresse (coping) mais utiliza é a experiência profissional na solução de dificuldades relacionadas ao trabalho.
STORYING KAITIAKITANGA: Exploring Kaupapa Māori land and water food stories
Authors: Hutchings Jessica , Smith Jo , Taura Yvonne , Harmsworth Garth , Awatere Shaun
Published: November 2020

This article explores the Indigenous principle of kaitiakitanga as it relates to Māori agrifood practices. Our discussion is based on interviews with a small cross-section of Māori in the agrifood sector whose practices are informed by a long-standing appreciation of the interconnected realities of lands, food, people and waterways. We consider how the shared Kaupapa Māori principles underpinning these food practices form part of a wider Kaupapa Māori land, water and food systems approach which we call “Kai Ora”. As is evident in the stories that follow, Kaupapa Māori values are practised in diverse ways by different kaitiaki food producers. For those who participate within any level of Māori food production, this kaupapa-based approach can lead to a range of connected outcomes, such as oranga, tātai hononga, tiaki taiao and ōhanga.
UNDERSTANDING PASIFIKA MENTAL HEALTH IN NEW ZEALAND: A review of the literature
Authors: Kapeli Sarah A. , Manuela Sam , Sibley Chris G.
Published: November 2020

Pasifika mental health continues to be a growing concern in New Zealand. This article reviews and presents online available research concerning the mental health of Pasifika in New Zealand. A comprehensive online literature search was conducted. In total, 967 online articles were identified, and 58 met the criteria to be included in the final review. The review identified overarching research themes related to Pacific mental health in New Zealand, specifically regarding mental health prevalence, mental health services, mental health perceptions, mental health prevention or intervention, and suicide. Further, this review explores the role that education, culturally appropriate services, and engaging community activities can play in preventing further mental health disparity among Pasifika in New Zealand.
O patrimônio histórico-educativo: a escola, o professor e as “rosas verdes”
Authors: Grim Thies Vania , Cruz Monks Joseane
Published: November 2020

O objetivo do artigo é analisar aspectos do patrimônio histórico-educativo da narrativa (auto)biográfica escrita nos diários manuscritos por uma mulher agricultora de 86 anos de idade. Esses manuscritos trazem relatos da autora sobre o trajeto percorrido até a escola, a arquitetura do espaço físico da mesma, o seu primeiro professor e sobre a materialidade de objetos de sua escolarização primária (1940). Os aspectos teórico-metodológicos estão baseados principalmente nos conceitos de cultura escolar e cultura material escolar, ancorados em autores como Escolano Benito (2017), Felgueiras (2015), entre outros. O artigo traz contribuições ao patrimônio histórico-educativo perpetuado, no caso dessa análise, pela memória e pela escrita presente nos diários analisados.
A Comprehensive Review on The Estimation of Emtricitabine
Individually and in Combination With other Drugs
Authors: Shaheen Rubi , Rizwan S.H.
Published: November 2020

Emtricitabine is a nucleoside reverse transcriptase inhibitor for the prevention of
HIV infection. This drug's, clinical and pharmaceutical analysis requires effective analytical
procedures and stability studies for quality control and pharmacodynamics and pharmacokinetic
studies. A comprehensive literature survey published in various journals related to analytical
and pharmaceutical chemistry was conducted and instrumental analytical methods were
developed and used in bulk drugs and pharmaceutical dosage form as single and combined with
other drugs. This review will critically examine UV spectroscopy analytical methods
(simultaneous equation method, derivative spectrophotometric method, absorption ratio and Qbased
method), High-performance liquid chromatography (HPLC), High-performance thinlayer
chromatography (HPTLC), Liquid chromatography coupled with tandem mass
spectrometry (LC-MS).
A New Stability Indicating RP-HPLC Method for
Determination of Chlorthalidone, Telmisartan and Cilnidipine
in Bulk and Tablet Dosage Form
Authors: Sultana S.Afreen , Salomi Patta. , VimalakKannan T. , Reddy K.Ravindra
Published: November 2020

In present study, accurate, precise, rapid and sensitive stability indicting HPLC-UV
method has been established for quantification of Telmisartan, Cilnidipine and Chlorthalidone
simultaneously in Tablet and bulk. Telmisartan, Cilnidipine and Chlorthalidone were resoluted
on Sunsil C18 column (4.6mmx250mm; 5μm) using mobile phase containing Acetonitrile and
Potassium dihydrogen phosphate in 50:50(v/v) ratio with flow rate of 1ml/min at 238 nm.
Concentrations were linear over the range of 40-120 μg/ml for Telmisartan, 10-30 μg/ml for
Cilnidipine and 6.25-18.75 μg/ml for Chlorthalidone. The percentage recovery was found to be
99.70-100.51% for Telmisartan, 98.41-100.49% for Cilnidipine and 99.34-100.48% for
Chlorthalidone. % RSD for peak area was 0.069% for Telmisartan, 0.058% for Cilnidipine and
0.057% for Chlorthalidone shows that the proposed method is precise. Force-degradation
studies have not shown any observable change in the results and hence the proposed method is
stability indicating and hence the method is suitable for routine analysis of Telmisartan,
Cilnidipine and Chlorthalidone in bulk and tablet dosage form.
Review of Present Trends and Future Scope of
Pharmacogenomics in Drug Discovery and Development
Process
Authors: Chandrakala V. , Sanki Utpal Kumar
Published: November 2020

Pharmacogenomics combines traditional pharmaceutical sciences such as
biochemistry with annotated knowledge of genetics, protein chemistry, and DNA
polymorphisms. The difference of therapeutic efficacy of the same drug in different individual
can be best explained by the study of genetic polymorphisms that underlie individual
differences in drug response. The small change of the genome in one individual may make a
drug inefficacious as oppose to the other patients. Such variability will bring the
individualization of the therapy to obtain the best effects of the drug, as an example autologous
dendrimer got a tremendous success in the cancer therapy of the individual.
Markers of exposure can determine whether the desired target tissues of a subject have been
exposed to a drug at physiological concentrations. Gene expression profiling is a tool that can be
used to characterize chemically induced toxicity in cells and/or animal models, in order to
provide plausible explanations for observed toxicity in preclinical testing.
Pharmacogenomics holds the promise that drugs might one day in future be tailor-made for
individuals and adapted to each person's own genetic makeup by the use of microarray
technology to express the gene which in turn helps to develop receptor protein. The stability of
the drug and its toxicity can be predicted prior to administration of the drug to the subject
through the knowledge of computer assisted structural simulation and DNA reactivity
technology respectively.
This article provides some critical aspects of drug developments, clinical trial design and ethical
issues which are centered with pharmacogenomics.
Green Stabilization of Clay Soil Using Cement Kiln Dust
Authors: Rama Rao P. Kodanda , Rajakumar C.
Published: November 2020

This research work is aimed to evaluate the suitability of cement kiln dust for
stabilization of expansive clay soil in Coimbatore. The laboratory work involved index
properties to classify the soil sample. The preliminary investigation of the soil shows that it
belongs to CH class of soil in the BIS soil classification system. Soils under this class are
generally of poor engineering use. Atterberg limits, free swell, free swell index, compaction,
UCS and CBR tests were used to evaluate properties of stabilized soil. The soil was stabilized
with cement kiln dust in stepped concentration of 5%, 10%, 15%, 20%, 25% and 30% by dry
weight of the soil. Analysis of the results shows that high improvement on the geotechnical
properties of cement kiln dust stabilized soil. Cement kiln dust reduces plasticity index, swelling
and MDD with an increase in OMC, UCS and CBR with all higher cement kiln dust contents.
From this study it was found out that cement kiln dust stabilized soil meet the minimum
requirement of IRC pavement specification for use as a sub-grade material in road construction.
Leveraging Delta Smelt Data for Juvenile Chinook Salmon Monitoring in the San Francisco Estuary
Authors: Mahardja Brian , Mitchell Lara , Beakes Michael , Johnston Catherine , Graham Cory , Goertler Pascale , Barnard Denise , Castillo Gonzalo , Matthias Bryan
Published: November 2020

Monitoring is an essential component in ecosystem management and leveraging existing data sources for multiple species of interest can be one effective way to enhance information when making management decisions. Here we analyzed juvenile Chinook Salmon (Oncorhynchus tshawytscha) bycatch data that has been collected by the recently established Enhanced Delta Smelt Monitoring program (EDSM), a survey designed to estimate the abundance and distribution of the San Francisco Estuary’s (estuary) endangered Delta Smelt (Hypomesus transpacificus). Two key aspects of the EDSM program distinguish it from other fish surveys in the estuary: a stratified random sampling design and the spatial scale of its sampling effort. We integrated the EDSM dataset with other existing surveys in the estuary and used an occupancy model to assess detection probability differences across gear types. We saw no large-scale differences in size selectivity, and while detection probability varied among gear types, cumulative detection probability for EDSM was comparable to other surveys due to the program’s use of replicate tows. Based on our occupancy model and sampling effort in the estuary during spring of 2017 and 2018, we highlighted under-sampled regions that saw improvements in monitoring coverage due to EDSM. Our analysis also revealed that each sampling method has its own benefits and constraints. Although the use of random sites with replicates as conducted by EDSM can provide more statistically robust abundance estimates relative to traditional methods, the use of fixed stations and simple methods such as beach seine may provide a more cost-effective way of monitoring salmon occurrence in certain regions of the estuary. Stronger inference on salmon abundance and distribution can be made by leveraging the strengths of each survey’s method. Careful consideration of these trade-offs is crucial as the management agencies of the estuary continue to adapt and improve their monitoring programs.
Non-Cannabinoid Metabolites of Cannabis sativa with Therapeutic Potential
Authors: Lowe Henry , Steele Blair , Bryant Joseph , Toyang Ngeh , Ngwa Wilfred
Published: November 2020

The Cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of different biogenetic classes. In addition to economic value, many of these phytochemicals have medicinal and physiological activity. The plant is most popularly known for its two most prominent and most studied secondary metabolites—
Δ9-Tetrahydrocannabinol (Δ9-THC) and Cannabidiol (CBD). Both Δ9-THC and CBD have a wide therapeutic window across many ailments and form part of a class of secondary metabolites called cannabinoids—of which approximately over 104 exist. This review will focus on non-cannabinoid metabolites of Cannabis sativa that also have therapeutic potential, some of which share medicinal properties similar to those of cannabinoids. The most notable of these non-cannabinoid phytochemicals are flavonoids and terpenes. We will also discuss future directions in cannabis research and development of cannabis-based pharmaceuticals. Caflanone, a flavonoid molecule with selective activity against the human viruses including the coronavirus SARS-COV2, and certain cancers, is one of the most promising non-cannabinoid molecules that is being advanced into clinical trials. As validated by thousands of years of the use of cannabis for medicinal purposes, vast anecdotal evidence abounds on the medicinal benefits of the plant. These benefits are attributed to the many phytochemicals in this plant, including non-cannabinoids. The most promising non-cannabinoids with potential to alleviate global disease burdens are discussed.
Analyze the FMCW Waveform Skin Return of Moving Objects in the Presence of Stationary Hidden Objects Using Numerical Models
Authors: Tang Taiwen , Wu Chen , Elangage Janaka
Published: November 2020

In this paper, a high-performance antenna array system model is presented to analyze moving-object-skin-returns and track them in the presence of stationary objects using frequency modulated continuous wave (FMCW). The main features of the paper are bonding the aspects of antenna array and electromagnetic (EM) wave multi-skin-return modeling and simulation (M&S) with the aspects of algorithm and measurement/tracking system architecture. The M&S aspect models both phase and amplitude of the signal waveform from a transmitter to the signal processing in a receiver. In the algorithm aspect, a novel scheme for FMCW signal processing is introduced by combining time- and frequency-domain methods, including a vector moving target indication filter and a vector direct current canceller in time-domain, and a constant false alarm rate detector and a mono-pulse digital beamforming angle tracker in frequency-domain. In addition, unlike previous designs of using M×N fast Fourier transform (FFT) for an M×N array, only four FFTs are used, which tremendously saves time and space in hardware. With the presented model, the detection of the moving-target-skin-return in stationary objects under a noisy environment is feasible. Therefore, to track long range and high-speed objects, the proposed technique is promising. Using a scenario having 1) a target with 17 dBm2 radar cross section (RCS) at about 40 km range with 5.93 Mach speed and 11.6 dB post processing signal to noise ratio, and 2) a strong stationary clutter with 37 dBm2 RCS located at the proximity of the target, it demonstrates that the root-mean-square errors of range, angle and Doppler measurements are about 26 meters, 0.68 degree and 1100 Hz, respectively.