bluuebunny/crossref_metadata_2025 huggingface dataset:
ÉTICA NA GESTÃO PÚBLICA: UMA ANÁLISE COMPARATIVA DE RESULTADOS DA PERCEPÇÃO DOS SERVIDORES PÚBLICOS A RESPEITO DO CÓDIGO DE ÉTICA
Authors: Mendes de Souza Valdenio
Published: December 2024

A ética na Gestão Pública é fundamental para a legitimidade e eficácia das instituições governamentais, garantindo a confiança da população por meio da transparência e responsabilidade. O comportamento ético dos servidores públicos, que administram recursos e políticas que afetam diretamente os cidadãos, é essencial para assegurar integridade e equidade nas suas funções. Este estudo investiga a percepção dos servidores públicos sobre a ética, analisando como esses profissionais compreendem e aplicam princípios éticos em suas atividades diárias. A abordagem permite identificar desafios na implementação de políticas éticas e as necessidades de formação para fortalecer a cultura ética no setor público. A análise é crucial para avaliar se os servidores atuam em conformidade com o Código de Ética, instrumento vital para a integridade no serviço público. Embora muitos servidores reconheçam a importância do Código de Ética, ainda há falhas significativas na sua aplicação, comprometendo a eficácia e a qualidade dos serviços prestados. A crise de valores e a falta de percepção sobre comportamentos antiéticos destacam a necessidade de fiscalização rigorosa e de programas de capacitação contínua. Este trabalho justifica-se pela necessidade de aprimorar a transparência e a eficiência na gestão pública, promovendo a fiscalização cidadã e institucional para melhorar os serviços oferecidos à sociedade. O objetivo principal da análise é verificar se os servidores públicos exercem suas atividades em conformidade com as normas e princípios estabelecidos pelo Código de Ética do Servidor Público. A metodologia empregada é descritiva e qualitativa, com métodos bibliográficos e documentais, organizados em seções que discutem o Estado, a Administração Pública, a ética e o impacto do Código de Ética na atuação dos servidores.
Protected Fats in High-Yielding Cows’ Diet: Effect on Lactation Performance
Authors: Nakonechny Alexander , Dydykina Alexandra , Volkova Natalya
Published: December 2024

The amount of fat in the diets of Kholmogory dairy cows is known to affect milk yield and its quality, as well as the economic efficiency of milk sales. In this research, the content of protected fats in the diets of high-yielding dairy cows was raised from 771.9 g to 1,023.9 g (32.6%) during full lactation by adding 300 g calcium salts of fatty acids per day. As a result, the milk yield increased by 8.0% (P = 0.95). The mass fraction of fat increased by 0.05% while that of protein rose by 0.03%, which improved the overall quality of milk. The experimental milk samples demonstrated a slight increase in non-fat milk solids (0.052%). The level of urea rose slightly (2.9 mg/100 mL) and reached 21.1 mg/100 mL, which corresponded to official standards and was a marker of a balanced diet. The study revealed a moderate positive correlation (r = 0.35) between the feed energy and the lactation performance. Protected fats had no significant effect on coagulation time and cottage cheese yield. The experimental diet demonstrated economic efficiency by increasing the potential profits from milk sales by 15.5%.
Modifying Structural and Mechanical Properties of Fermented Dairy Products with Various Biological Pectins
Authors: Kondratenko Vladimir , Fedotova Olga , Agarkova Evgeniya
Published: December 2024

Pectins can modify structural and mechanical properties of fermented dairy products. The article introduces a new approach to determining the applicability of pectins from various bioresources for this purpose. Pectins from various sources were ranked in descending order within each of the target technological properties based on their molecular characteristics and physicochemical parameters. This approach revealed the optimal pectins to modify the technological properties of particular dairy products. The pectin samples were obtained from sugar beet pulp, citrus peels, apple pomace, sunflowers, pumpkin pomace, carrot cake, and potato cake. They were introduced into formulations of yogurt, fermented milk drink, acidophilus sauce, sour cream, and fermented milk jelly. No major molecular factor affected the correlation between the molecular properties of pectins and the manifestation of their technological properties in the fermented dairy pectin-containing products. As a result, all molecular characteristics were taken into account as a complex. A nonlinear increase was detected in the dynamic viscosity of yogurt, fermented milk drink, acidophilus sauce, and sour cream. It correlated with the increase in the mass fraction of pectin, which made it possible to vary the consistency of the product depending on consumer preferences. With regard to fermented dairy jelly, ≥0.8% pectin resulted in an excessive density. In some cases, combinations of pectins had a more synergistic effect on viscosity and gelling ability than separate applications.
Bifidogenic Feed Additive Based on Secondary Dairy and Plant Raw Materials
Authors: Kaledina Marina , Vitkovskaya Viktoria , Voloskova Yulia , Litovkina Daria
Published: December 2024

Gastrointestinal infectious diseases accompany the growth of animal and poultry farming: as the livestock population increases, its high concentration on farms raises the level of mortality and rejection, thus reducing the overall safety and productivity. Probiotics and prebiotics used as feed additives may be an effective preventive measure. The article describes a sustainable and environmentally friendly method for obtaining prebiotics of pectin oligosaccharides by hydrolyzing apple pomace pectin in whey with Saccharomyces cerevisiae to produce bifidogenic animal feed. The 5:1 ratio of whey and apple pomace increased the yeast biomass by 56.3% after 24 h of fermentation and introducing 0.3% yeast by weight. The pectin hydrolysis products triggered an intensive growth of the substrate. The hydrolysis products contained 32% oligosaccharides of average molecular weight. The enzymatic hydrolysis of whey-apple mixes with a β-galactosidase preparation by deep cultivation of Bacillus licheniformis prevented the negative effect of serum lactose consumption, as well as increased the yield of yeast biomass. The optimal hydrolysis parameters were pH 6.0, 25 °C, 0.04% enzyme, and 6 h. The technological process included the following stages. The raw materials were prepared as a whey-vegetable mix (5:1), which was gradually heated to 65 °C. After cooling down to 22-25 °C, dry Saccharomyces cerevisiae provided fermentation and deoxidation. After introducing lactase enzyme and final thermal treatment, the finished feed additive contained 10% solids, 3.5% nitrogenous substances, 0.6% pectin, 0.3% pectin oligosaccharides, and 0.2% residual lactose, as well as vitamins and minerals.
effect of k -casein genotypes on milk yield in second-generation dairy cattle
Authors: Khudyakova Natalya , Kudrina Marina , Klassen Inga
Published: December 2024

Improving the qualitative and quantitative characteristics of milk is crucial for national food safety. Genetic marker selection demonstrates good prospects in this regard, the most promising genetic marker being k-casein, or kappa-casein. The AB and BB genotypes of k-casein are associated with such positive milk properties as high protein content, good coagulation, and increased yield of cottage cheese or cheese. The research objective was to identify inheritance patterns in female calves obtained from cows with various genetic backgrounds. These results were checked for correlation with milk yield indicators. The experiment featured cows of the Kholmogorsky breed and their female calves. It was conducted in 2023 on the premises of two breeding farms, i.e., Kholmogorskaya Plemzavod and Kholmogorskaya Agrofirma. The DNA was isolated using a set of MagnoPrime VET reagents. The polymorphism test of the k-casein gene was performed by the RELF PCR method. The experiment revealed the frequency of occurrence of genotypes and alleles of the k-casein gene. In both farms, A allele was more frequent in both mother cows and calves than the B allele. The AA genotype predominated in both generations. In Kholmogorskaya Plemzavod, the highest milk yield (6,741 kg) belonged to the calves with a homozygous genotype for allele A, which they received from their mothers with a heterozygous genotype. A similar trend (6,008 kg) was established in calves with a homozygous genotype for allele B, which they inherited from their mothers with a heterozygous genotype AB. In Kholmogorskaya Agrofirma, the highest milk yield (7,592 kg) was observed in the second-generation cows with a homozygous BB genotype, which they received from their mothers with a heterozygous AB genotype.
Strategical Priority of Regions for Integrated Development in Russia
Authors: Monosov Andrey
Published: December 2024

Regions to participate in integrated development programs can be strategically prioritized. In this study, a review of global best practices made it possible to design a model of territorial development with its basic and strategic quantitative parameters. The model parameters included average annual working population, average gross regional product per citizen, total residential area per citizen, volume of construction activity, number of residential buildings commissioned, number of broadband Internet users per 100 population, working urban and rural residents, etc. The author applied these rating indicators to eight federal districts in order to identify first priority areas for integrated development. The article also contains some general conclusions on the territorial development in the Russian Federation.
Strategic Motivation System in Innovative Business
Authors: Novikova Irina , Samaybekova Zeynegul
Published: December 2024

Modern businesses have to be adaptable, innovative, and strategically focused on long-term prospects. Innovations allow companies to adapt to the rapid economic changes in the context of digitalization and global competition. Innovative development depends on employees who are ready for continuous learning and search for new solutions. In this regard, an innovative enterprise requires an effective system of strategic motivation that reveals the labor potential of its staff and encourages their active participation in innovations. The article describes the strategic motivation system as part of an innovative business. The authors studied the most relevant definitions of strategic motivation, analyzed the impact of strategic motivation on labor activity, and identified the basic development principles for an effective strategic motivation system. This research relied on the theory of strategy and the methodology of strategizing developed by Professor V. L. Kvint. It also featured a comprehensive review of scientific publications on strategic motivation in innovative development. The article introduces an authentic interpretation of innovative strategic motivation, its principles, and an assessment scale, as well as means of increasing personnel involvement. An efficient strategic motivation system encourages the innovative activity of employees, as well as increases their professional skills, performance, and labor potential, which ultimately improves the strategic results of an innovative company.
Hybrid feedforward-feedback LQR controller based on model prediction for open channel water level control
Authors: Li Xiaohua , Guan Guanghua , Tian Xin , Luo Yufeng , Huang Yuequn , Yang Jialiang
Published: December 2024

Linear quadratic regulator (LQR), as one of the most popular optimal feedback controllers, has been used in open-channel automatic control. However, existing hybrid feedforward-feedback controllers are simple combinations lacking consistency and neglect the potential of model prediction in the feedforward part. This paper presents a novel hybrid linear quadratic regulator (HLQR) controller with a feedforward-feedback structure. Rather than achieving feedforward control by compensation of discharge or volume, HLQR incorporates a water level prediction of the canal model into the conventional LQR, allowing consistent optimal control and flexible adjustment of weight coefficients in both feedforward and feedback parts. The designed hybrid controller can provide a simple effective way for canal control. It has been numerically tested in a test canal compared with the discharge compensation linear quadratic regulator (DCLQR). Results show that the proposed HLQR can reduce the water level fluctuations and shorten the transition time. The maximum absolute error of the water level can be reduced by 56.65%, the gate movement is decreased by 69.69%, and the transition time is cut down from 21.5 to 7.5 h. With outstanding control performance, the proposed HLQR controller can promote water distribution practically and flexibly, showing great potential in hydraulic control.
Prediction of contraction channel scour depth: based on interpretability analysis and PCA-enhanced SVR
Authors: Wang Yibo , Liu Yakun , Cao Ze , Zhang Di
Published: December 2024

Due to the numerous uncertain factors affecting contraction scour depth, although many traditional empirical formulas have been proposed in past research, their prediction accuracy is generally low. In recent years, with advancements in machine learning (ML) technology, these techniques have been able to accurately capture the nonlinear characteristics of scour-depth data. However, in pursuit of higher prediction accuracy, researchers have explored a wide range of diverse ML models that require various combinations of input parameters. These input parameter combinations often lack reliability, and the models themselves have poor interpretability, increasing the ‘black-box effect.’ Therefore, this study uses a principal component analysis (PCA)-enhanced support vector regression (SVR) model to construct a scour depth prediction model, combined with the interpretability method of SHapley Additive exPlanations (SHAP). The results show that the SVR model's predictions are highly consistent with physical experimental laws, and the model primarily identifies features that are strongly linearly correlated with the dependent variable (scour depth and SHAP values). The application of PCA enhances the correlation, and when using the CC-PCA-4 input parameter combination, the SVR model achieves high accuracy (R2 = 0.971, mean absolute percentage error = 7.54%). Moreover, its comprehensive evaluation in terms of stability, accuracy, and conservativeness surpassed that of other ML models and empirical formulas.
Influence of sewage effluent discharge on putative pathogen community in drinking water sources: insights from full-length 16S rRNA gene amplicon sequencing
Authors: Zeng Jie , Nakanishi Tomohiro , Hara Ayato , Itoh Sadahiko
Published: December 2024

The discharge of sewage effluent is a major source of microbial contamination in drinking water sources, necessitating a comprehensive investigation of its impact on pathogenic bacterial communities. This study utilized full-length 16S rRNA gene amplicon sequencing to identify putative pathogenic bacteria and analyze their community structures in drinking water sources subjected to different levels of fecal pollution: urban rivers with low, moderate, and high sewage effluent mixing ratios, and mountain streams with minimal human impact. The sewage effluent itself was also analyzed. Mountain streams primarily harbored environmental pathogens, whereas urban rivers exhibited significantly higher concentrations of fecal indicator bacteria (FIB) (i.e., Escherichia coli and Clostridium perfringens) along with markedly more diverse enteric pathogens with a higher relative abundance. Furthermore, within urban rivers, the putative pathogen communities displayed significant variation, closely aligning with the sewage effluent mixing ratios. The effectiveness of FIBs as indicators of enteric pathogens was found to be largely dependent on the levels of fecal pollution. This study offers novel insights into the impact of sewage effluent discharge on putative pathogenic bacterial communities with enhanced species-level resolution.
Study of the combined effect of temperature and free chlorine concentration on the chlorine bulk decay coefficient in water supply systems
Authors: Mompremier Rojacques , León Santiesteban Héctor Hugo , Ramírez Muñoz Jorge , Gómez Núñez Jersain
Published: December 2024

The chlorine bulk decay coefficient (kb) is a crucial parameter for modeling the chlorine decay process within drinking water distribution systems. In this study, the combined effect of temperature and chlorine concentration on kb was investigated. A central composite design (CCD) was employed. Ten scenarios were conducted on a pilot-scale pipeline network with initial chlorine concentrations from 0.38 to 4.62 mg/L and water temperature from 22.93 to 37.07 °C. A statistical analysis of the kb obtained in the experiments was conducted using STATGRAPHICS software. An analysis of variance (ANOVA) for Log10(kb) was also performed to segregate the combined contributions of chlorine and temperature effects. Chlorine concentration and temperature are factors that significantly affect kb. However, the temperature effect is marginal compared to that of the chlorine concentration. A quadratic model obtained from CCD data effectively predicted the kb within the proposed experimental zone, although its utility may be limited at lower temperatures. The combined effect of chlorine concentration and temperature on the Log10(kb) is shown on the response surface obtained from the quadratic prediction model of kb. Analysis of the response surface revealed that the operating conditions of 22.3 °C and 3.33 mg/L, respectively, yield the minimal value of kb = 0.0347 h−1.
Effects of low temperature on the microbial community of MBBR filler biofilm
Authors: Zhu Xiaoxiao , Chang Wenjie , Kong Yu , Cai Ying , Huang Zhaoming , Wu Tianqi , Zhang Miao , Nie Huijun , Wang Yuan
Published: December 2024

Moving bed biofilm reactors can purify urban domestic sewage through microbial biodegradation. High-throughput sequencing was used to study the response mechanism of the biofilm microbial community to temperature. The effluent quality of the reactor declined with the decrease in temperature. Proteobacteria, Bacteroidota, and Nitrospirota were the dominant bacteria, accounting for 59.2, 11.9, and 9.4%, respectively. Gammaproteobacteria (38.3%), Alphaproteobacteria (23.2%), and Bacteroidia (12.4%) were the dominant bacteria at the class level. Low temperature had an obvious directional domestication effect on microbial flora, and the composition of the bacterial community was more similar. Pseudomonas was one of the dominant bacterial groups at 5 °C. Nitrospira (p < 0.001) and Trichococcus (p < 0.05) were significantly negatively correlated with effluent ammonia nitrogen and significantly positively correlated with NO3− (p < 0.05) at low temperature. Functional bacteria related to chemoheterotrophy (25.88%) and aerobic_chemoheterotrophy (21.56%) accounted for a relatively high proportion. The bacteria related to nitrate reduction only accounted for 2.62%. Studies have shown that low temperatures can inhibit the growth of nitrogen-cycling bacteria, and few domesticated and selected nitrogen-cycling bacteria play a major role in the removal and transformation of ammonia nitrogen. The degradation of chemical oxygen demand can still be achieved through the adsorption and degradation of dominant functional bacteria.
Inmisiones y relaciones de vecindad: desde la aproximación casuística a la regulación del Código Civil italiano
Authors: Tuccillo Fabiana
Published: December 2024

Para llenar el vacío legislativo, especialmente tras el aumento del número de casos de inmisiones que causaban daños a los vecinos, el legislador italiano introdujo en 1942 un nuevo artículo en el Código Civil, el artículo 844, basado en diversas pronunciaciones jurisprudenciales y las opiniones y sugerencias de eminentes juristas y académicos italianos. El legislador intentó establecer criterios para regular los casos de inmisiones tolerables e intolerables, intentando equilibrar el interés de la propiedad privada plena y exclusiva y los intereses de la economía y la industria.
Assessment of the Knowledge of H. pylori Infection, Diagnosis, and Management among the General Population in the Western Region, Saudi Arabia
Authors: Hariri Nahla H. , Makkawi Deema K. , Alkabkabi Shahad S. , Elzahrany Rania R. , Albrnawi Saja H. , Bawahab Nizar S. , Alqashqri Hamsah S. , Alsanosi Safaa M. , Alfalogy Enas H.
Published: December 2024

Background:

Helicobacter pylori (H. pylori) is the most prevalent chronic bacterial infection in humans. Limited research has been conducted both
internationally and locally to evaluate the general community’s collective understanding of an H. pylori infection, its diagnosis, and its
management.

Objective:

This study aims to evaluate the level of understanding of an H. pylori infection, its diagnosis, and management among the general population
residing in the western region of Saudi Arabia.

Methods:

The study employed a cross-sectional online survey method to gather data from a sample of 1,025 of the general population. Four major cities were
selected for this study: Makkah, Madinah, Jeddah, and Taif. The knowledge scores were classified into three categories: low, fair, and good.

Results:

The proportion of the population with a fair level of knowledge of H. pylori was less than 30% in all groups of the cities. A statistically significant
difference was observed between regions, with a P value of 0.022. Furthermore, there was a strong correlation between the respondents' degree of
knowledge and age (p < 0.001), education level (p < 0.001), number of family members at home (p < 000.1), monthly income (p < 0.001),
knowledge about an H. pylori infection (p < 000.1), and previous exposure to an H. pylori infection (p < 000.1).

Conclusion:

Most participants know about H. pylori. However, its transmission, link with stomach cancer, diagnosis, and treatment are difficult to understand.
Several additional educational and policy interventions are recommended to enhance public knowledge of H. pylori. To address the identified gaps
in understanding, targeted educational campaigns should be developed.
FHL1 Inhibition by Mir-1301-3p Promotes Uterine Corpus Endometrial Carcinoma Cell Proliferation and Migration: A Prognostic Insight
Authors: Zhu Mengna , Chen Buze , Miao Lu , Sun Jieyun , Li Yuanyuan , Zhang Pei , Lu Xiaoyuan
Published: December 2024

Background:

The impact of microRNA-1301-3p (miR-1301-3p) on various
cancer subtypes is noteworthy. However, its specific role within the framework of
uterine corpus endometrial carcinoma (UCEC) is yet to be clearly defined.

Objective:

The objective of this research was to investigate and clarify the function of
miR-1301-3p in relation to UCEC.

Methods:

Sample data for our study were sourced from The Cancer Genome Atlas (TCGA).
Using various statistical techniques, we assessed the potential of miR-1301-3p as a
diagnostic and prognostic indicator, as well as its association with clinical characteristics.
Additionally, we conducted an analysis of the genes targeted by miR-1301-3p. The
expression levels of miR-1301-3p in uterine corpus endometrial carcinoma (UCEC) cell
lines were determined by quantitative real-time PCR (qRT-PCR). Cellular viability and
migratory capacity were measured using the CCK8 assay and Transwell migration assays,
respectively. Moreover, the expression levels of genes and proteins targeted by
miR-1301-3p were identified through dual-luciferase reporter gene assays and Western
blot analysis.

Results:

Expression patterns of miR-1301-3p varied across cancer subtypes, which were
significantly linked to specific histological classifications, achieving statistical significance
(p < 0.001). In UCEC, higher miR-1301-3p levels correlated with reduced overall
survival (p = 0.012) and progression-free survival (p = 0.016), and it emerged as an independent
prognostic marker for UCEC. A comparative analysis revealed significantly
higher miR-1301-3p levels in UCEC cell lines compared to normal endometrial epithelial
cells. Four and a half LIM domains 1 (FHL1) exhibited a negative correlation with
miR-1301-3p levels within UCEC tissue samples. miR-1301-3p was shown to promote
UCEC cell proliferation and migration through its binding to the 3'-untranslated region
(UTR) of the FHL1 gene, thereby repressing FHL1 expression. Additionally, augmenting
FHL1 levels was observed to counteract the enhancing impact of miR-1301-3p on
UCEC cells.

Conclusion:

miR-1301-3p regulates the proliferation and migration of UCEC cells by interacting
with the FHL1 gene. miR-1301-3p may serve as a promising prognostic biomarker
in UCEC.
Advancements and Patent Trends in Deflector Jet Tube Electro-Hydraulic Servo Valves
Authors: LI Jianying , Chen Wanting , Wang Zhao , Guo Qi
Published: December 2024

Deflector plate jet servo valves are mostly used in high-temperature and high-pressure
situations, and are widely used in both military and industrial applications. The deflector plate servo
valve does not need a winding oil supply pipe, which overcomes the vibration that may occur in the
structure. Although the deflector jet tube-type electro-hydraulic servo valve is widely used, its structure
is complex, involving a large volume, which makes it easy to produce noise and cause oil leakage
and other problems; its characteristics are prone to be affected by the temperature. Also, due to
the complexity of its internal flow field, it is prone to erosion and wear phenomena. This paper, thus,
aimed to overcome these shortcomings by collecting data from the works and patents that have focused
on improving these characteristics. It has been found that a large number of scholars have analyzed
the characteristics of the pre-stage flow field by establishing models and fluid simulations,
focusing on the thermal characteristics under the influence of temperature and the internal problems
under the influence of erosion and wear, and put forward a large number of structural optimization
and improvement schemes. In view of the pressure and flow output of the deflector jet tube type
electro-hydraulic servo valve, the difficulty of structural processing, the difficulty of structural assembly
and adjustment, the weakening of structural strength, the influence of component wear and
the interference of deflection plate displacement, etc., we have summarized the relevant patents both
at home and abroad, and discussed how to improve the deficiencies of the deflector jet tube type
electro-hydraulic servo valve. By summarizing a large number of articles and patents, it has been
found that the deficiencies of the deflector jet tube type electro-hydraulic servo valve still need to be
explored and overcome by more scholars. Domestic and foreign research on the characteristics of the
deflector jet tube type electro-hydraulic servo valve is relatively deep, but the research on some key
technologies of this valve is still insufficient and needs to be conducted in the future.
Patented Automated Feeder Robot: Integrating Food and Water Dispensing, Camera System, and Wheeled Mobility
Authors: Jayaprakash V. , S.S Aravind Kumar , J.R. Deepak , M. Anish , Nivin Joy , J. Jayaprabakar
Published: December 2024

Introduction:

This patent article introduces a pet feeding robot designed patent to address
challenges related to pet owners' availability and pet hygiene during feeding times.

Method:

Utilizing the Arduino Uno as the central controller, along with various components such
as actuators, pumps, motors, cameras, and servo motors. The aim of this project is to streamline
the development of an automated pet feeding system. The Smart Pet Feeding Machine employs a
time-based mechanism to autonomously dispense food and water using a pump motor.

Result:

It features a vertical storage unit for both food and water, alongside a motorized dispenser
equipped with a wheeled DC motor for robot movement. Mobility of the dispenser is controlled
by a servo motor, while live streaming capabilities are enabled through the attachment of a camera
facilitated by NodeMCU.

Conclusion:

Furthermore, sensors are integrated to accurately gauge the distance between the
robot and its target items.
Synthetic Development of 3-Functionalized Benzanthrone as a Fluorophore for Various Uses
Authors: Patel Meet B. , Trivedi Vidhi A. , Dabhi Ranjitsinh C. , Maru Jayesh J. , Patel Zeelu M.
Published: December 2024

This review comprehensively explores the synthetic development, photophysical properties,
and diverse applications of 3-substituted benzanthrone derivatives. These derivatives, functionalized
at the C-3 position, exhibit exceptional fluorescence, photostability, and tunability, making
them highly versatile in fields, such as organic electronics, dye chemistry, and photodynamic
therapy. Benzanthrone-based compounds are pivotal in the development of advanced materials, including
organic semiconductors for flexible electronics and daylight fluorescent pigments. This review
highlights innovative synthetic methodologies, from traditional approaches to eco-friendly
techniques, emphasizing their impact on the efficiency and environmental sustainability of these
compounds. The discussion extends to the potential of benzanthrone derivatives as photodegradation
inhibitors and their promising role in next-generation laser dye technologies. By integrating
these derivatives into various applications, this review underscores their critical importance in advancing
material science and technology, paving the way for future innovations.
Review Understanding of the many Facets of Cancer and the Management of Skin Cancer
Authors: Saloki Arushi , Shrivastava Aditya , Gaikwad Sarita , Saraf Swarnlata
Published: December 2024

Cancer is a complex disorder characterized by the unregulated proliferation of cells that have the potential to invade other regions of the body. It
stems from genetic alterations in various cell types, resulting in tumor formation. These growths are classified as benign (noncancerous) or
malignant (cancerous). Unlike benign tumors, which typically remain localized, malignant tumors can spread, infiltrate nearby tissues, and
establish secondary growth in organs far from the original site. The treatment approach depends on the specific type and progression of cancer,
encompassing options such as surgical intervention, radiation-based therapies, drug-based treatments, immune system-boosting techniques, and
therapies targeting particular cellular mechanisms. Skin cancer is a common occurrence among various cancer types, especially in populations with
lighter skin tones. Skin cancer is a prevalent form of cancer, particularly in the Caucasian population. The most common skin cancers are basal cell
carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma. BCCs, which arise from the basal layer of the epidermis, are often treated with
surgery, topical therapies, or cryotherapy depending on their risk and location. Mohs micrographic surgery is effective for high-risk or recurrent
BCCs, whereas topical treatments such as 5-fluorouracil and imiquimod are used for superficial BCCs. Early diagnosis through biopsy and various
imaging techniques is crucial for effective management. Advances in treatment, including targeted therapies and improved surgical techniques,
continue to enhance patient outcomes and reduce recurrence rates. Understanding these diverse aspects of cancer and skin cancer will help devise
effective treatment strategies and improve patient prognosis.
A Survey on the Communication of UAVs with Charging and Control Stations
Authors: Chalkiadaki Aikaterini , Milidonis Athanasios , Mourgelas Christos , Voyiatzis Ioannis
Published: December 2024

Unmanned Aerial Vehicles (UAVs) have a history of over a century of deployment,
but in recent decades, they have progressed at a staggering rate. Nowadays, UAVs are used by
a large number of civil and military applications. The communication functionality of a UAV
with external systems for control and charging is strongly connected with evolving technologies
and services. This leads to an increased number of alternatives when designing UAV
communications. This review presents the information needed for choosing an efficient communication
system between UAVs and two important elements, the Ground Control Station
(GCS) and the Charging Station (CS). GCS is responsible for monitoring and controlling the
UAV’s units, while CS is used for the formal charging of the UAV. This study aimed at collecting,
classifying, and evaluating all of the necessary information in order to obtain the final decision
about the kind of communication that is most efficient for a target UAV application.
The features of the telemetry open-source protocols are presented for the UAV-GCS communication
and evaluated according to the needs of the most significant application domains.
Communication between UAVs and CSs is classified depending on the existence of an intermediate
server and analyzed considering telemetry protocols and application domains. Communication
algorithms are evaluated in terms of time and energy efficiency. Lastly, for the
most significant application domains, the most suitable algorithms are matched.
Probiotics in Mitigating Adverse Effects of Intestinal Resection and Chemotherapy: A Meta-analysis
Authors: Furnari Salvatore , Furneri Pio Maria , Fuochi Virginia
Published: December 2024

Introduction:

Colorectal cancer (CRC) imposes a significant burden on global healthcare
systems, particularly in Europe, where it ranks among the most diagnosed cancers and leading causes
of cancer-related deaths. With an estimated 50,000 deaths attributed to CRC in 2023 alone, a
pressing need for innovative approaches to prevention, early detection, and treatment is evident.
While chemotherapy and surgical resection remain crucial therapeutic strategies, they often entail
significant adverse effects, such as chemotherapy-induced diarrhea and post-surgical complications.

Methods:

Recent research underscores the role of the microbiota in modulating these side effects,
with dysbiosis associated with increased risks. Probiotics, known for their ability to restore microbial
balance, have emerged as a promising adjunctive therapy for mitigating treatment-related complications
in CRC patients. However, the efficacy of probiotics remains debated, necessitating a metaanalysis
to provide a comprehensive assessment. Hence, this study aimed to evaluate the efficacy of
probiotics in reducing complications in CRC patients undergoing chemotherapy and intestinal surgery.
For this purpose, thirteen randomized controlled trials (RCTs) meeting strict inclusion criteria
were included in the meta-analysis.

Results:

Probiotic administration was associated with significant reductions in postoperative infections,
including surgical site infections (SSI), pneumonia, urinary tract infections (UTI), and central
line infections, showing a Risk Ratio (RR) of 0.74 with a Confidence Interval (CI) of 95%. Moreover,
probiotics demonstrated efficacy in mitigating chemotherapy-induced diarrhea and postsurgical
complications, such as anastomosis loosening and abdominal disorders, with an RR of 0.35
and 0.74, respectively, with a CI of 95%. While promising, further research is needed to optimize
probiotic interventions and address potential interactions with concurrent therapies. Integrating probiotics
into perioperative care protocols presents a convincing opportunity to enhance surgical outcomes
and improve patient prognosis following CRC resection.

Conclusion:

Future randomized controlled trials should focus on identifying optimal probiotic
strains, dosages, and administration timing to maximize therapeutic benefits.
Production and Characterization of Pomelo Albedo Powder Based Pasta: Physicochemical, Functional, Textural and Sensorial Attributes
Authors: Sharma Simple , Singh Barinderjit , Srivastava Yashi
Published: December 2024

Background:

Pomelo albedo peel byproducts are composed of many health-ben-eficial phytochemicals during processing. This study aimed to maximize the potential of incorporating pomelo albedo powder as a bioactive ingredient in pasta.

Methods:

In the present study, pomelo albedo was fortified with pasta at five different con-centrations (0, 3, 6, 9, and 12%), and its effects on the antioxidant, functional, textural, and sensorial attributes of pasta were investigated.

Results:

The results showed that the incorporation of albedo powder remarkably elevated the antioxidant properties and significantly increased the WAC (121.23 to 188.97%) and OAC (110.15 to 136.55%). An increase in pomelo albedo is associated with a decrease in cooking time from 10.24 to 8.28 min with cooking loss that is within an acceptable range. The pomelo albedo formulation improved the color and sensorial attributes. A higher albedo concentration significantly reduced the breaking stress, fracturability, firmness, and hard-ness but increased the adhesiveness and cohesiveness of pasta. FTIR spectra revealed the presence of characteristic peaks, and SEM reflects pomelo albedo's impact on the structural integrity of the pasta.

Conclusion:

On the basis of physiochemical, cooking, and sensory data, pasta with a 6% pomelo albedo formulation was found to be the most acceptable, with an overall acceptabil-ity of 8.51. Thus, pomelo albedo can be incorporated into the industry for the preparation of pasta with enhanced nutritional characteristics.
Design Thinking, social entrepreneurship and cross-cultural dialogue: A case study of a trinational virtual exchange
Authors: Cheikhrouhou Nadia , Gilbrecht-Hindi Alia
Published: December 2024

This practice report explores the integration of Design Thinking (DT) into virtual exchange (VE) projects to enhance students’ engagement with Sustainable Development Goals (SDGs). Despite increasing interest in VE and SDGs, there is a lack of research on effective DT practices in VE contexts. This paper fills this gap by identifying best practices: integrating intercultural dialogue principles, fostering multicultural collaboration, and assigning coaches to student teams. These strategies were implemented in a VE involving three institutions across the Middle East, North Africa, and the U.S. Results from both a quantitative survey and qualitative reflections indicate that the combination of DT, intercultural dialogue, and effective coaching not only facilitated students’ understanding and engagement with global issues related to SDGs but also enhanced their professional skills such as creativity, collaboration, and critical thinking. This paper contributes best practices for educators aiming to leverage DT for SDGs in VE settings.
Factores que afectan la germinación de tres pastos de zonas áridas: Leptochloa crinita, Pappophorum caespitosum y Digitaria californica (Poaceae)
Authors: Meglioli Carola , Scaglia Juan Antonio , Parera Carlos Alberto
Published: December 2024

Antecedentes y Objetivos: Los pastizales constituyen la vegetación principal de las tierras áridas; sin embargo, en muchos casos se encuentran degradados debido a una combinación de factores naturales y antrópicos. Una estrategia para recuperar estas tierras es la siembra de especies forrajeras anuales o perennes nativas tolerantes a temperaturas altas, elevados niveles de insolación, déficit hídrico, y capaces de crecer en suelos pobres o salinos. El objetivo de este trabajo fue explorar el efecto de factores abióticos sobre el desempeño germinativo de tres especies abundantes de pastos de zonas áridas: Leptochloa crinita, Pappophorum caespitosum y Digitaria californica.Métodos: El porcentaje de germinación (G) y el tiempo medio de germinación (TMG) se evaluaron en condiciones de luz y oscuridad, en presencia y ausencia de espiguillas, y a cinco temperaturas constantes (15, 20, 25, 30 y 35 °C). En una cámara de germinación fueron sembradas 25 espiguillas o cariopses desnudos en cajas de Petri estériles con papel de germinación neutro, se regaron con agua destilada y se dispusieron al azar. El conteo de la germinación (radícula visible) se realizó cada 24 h, durante 5 días. Resultados clave: La luz tuvo un efecto positivo en la germinación de L. crinita y P. caespitosum. La germinación de D. californica disminuyó considerablemente a 15 y 35 °C. La espiguilla fue el factor con mayor efecto negativo sobre la germinación de las tres especies. La triple interacción de los factores indicó que las tres especies poseen mejor desempeño germinativo en presencia de luz, con temperaturas entre 20 y 25 °C, y en ausencia de la espiguilla.Conclusiones: Las tres especies podrían ser utilizadas en programas de recuperación de tierras degradadas en zonas áridas, debido principalmente a su plasticidad para germinar a diferentes temperaturas, con incidencia de la luz. Los cariopses desnudos aumentan el porcentaje de germinación y mejoran el TMG.
Structure and Monitoring in the Seismic Activation Zone of the Gorlovskaya Depression of the Altai-Sayan Folded Region According to Electrical Resistivity Tomography Data
Authors: Nevedrova Nina , Shalaginov Aleksandr , Shaparenko Il'ya , Sanchaa Aydisa , Marinenko Arkadiy
Published: December 2024

In the last decade, the intensity of development of the Gorlovskoye coal deposit has increased significantly, which leads to the formation of seismic activation of the subsoil of the Gorlovka depression in response to man-made impact. Since 2019, earthquakes with a magnitude of more than 4 have been recorded in the area of the deposit, felt in Novosibirsk and its suburbs. The main objective of the study: as data accumulates, to identify the criteria for seismic activations using one of the methods of ground-based electrical exploration – electrical resistivity tomography. The article considers the geoelectric structure of the Gorlovka depression in the area of the transition from its deposits to the Salair ridge, and also analyzes the results of monitoring carried out in 2023 by the electrical resistivity tomography method along a profile intersecting one of the fault structures. The monitoring observation profile is located on a site selected during experimental and methodological work and is located just a few kilometers from coal quarries and the zone of concentration of seismic events. It was found that the identified variations in geoelectric parameters reflect the reaction of the geological environment not only to earthquakes occurring during the observation period, but also to man-made impacts (explosions).
“No Viral, No Justice”: Unveiling the Phenomenon of Digital Vigilantism from a Psychological Perspective
Authors: Angela Lisa , Aulia Wina , Rahma Balya Galuh Jiehan Safira
Published: December 2024

The rapid advancement of the cyber world has spurred new behaviors and a complex transition from real-life to online behaviors. One behavior arising from this development is digital vigilantism. This concept utilizes social media and the internet to punish or publicly shame those perceived as normatively guilty. Using a narrative literature review method, this article aimed to explore digital vigilantism behavior and analyze it through the lens of psychology. The literature review examined seven research articles discussing digital vigilantism published from 2014-2024. Key focuses include the concept of digital vigilantism, analysis based on psychology theories (such as social identity theory and theory of justice), as well as an examination of its strengths and weaknesses. The article provides fresh insights into digital vigilantism and its intersection with psychology.
The Influence of The Speaker's and Hearer's Age on Request Strategies Used in the Movie Yours, Mine & Ours
Authors: Salsabila Aflah Nuraini , Basuki Amin
Published: December 2024

This research aims to analyze request strategies in the movie Yours, Mine & Ours (2005). In particular, it attempts to identify and classify request strategies used by the main characters in the movie using the theory of request strategies proposed by Blum-Kulka and Olshtain (1984). This research also analyzes the differences of request strategies influenced by speaker's and hearer's age which are divided into four age groups: adult, teenager, pre-teen, and children. The data used in this research are all utterances containing requests made by the main characters in the movie. In Yours, Mine & Ours, the requests occur in the family domain and informal situations. The results show that the strategy that is most used by all age groups is Mood Derivable, which belongs to Direct Strategy. It also shows that adult is the age group that uses Direct Strategy the most and uses more types of strategy than the other age groups. Furthermore, the research also found that all age groups prefer to use Mood Derivable when the hearer is from the same and younger age group. Meanwhile, when the hearer is from older age group, the speaker prefers to use Reference to Preparatory Conditions.
Defending the Best Interest Principle: Caring for Critically Ill Children
Authors: Huq Ambareen
Published: December 2024

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An In-Depth Examination of the International Climate Regime: Spotlight on Nationally Determined Contributions and Paris Agreement Compliance
Authors: Bouniol Margaux
Published: December 2024

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To Break the Fourth Wall: A Comparative Approach to Scottish Ministers, Petitioners
Authors: Etchells Samuel
Published: December 2024

The decision of the Secretary of state for Scotland to use a section 35 order to 'veto' the Gender Recognition Reform (Scotland) Bill was met with controversy. In some quarters, it was considered a necessary means of prevening the Scottish Parliament from interfering with UK-wide equality law. In others, it was branded as an unacceptable intrustion on the devolved law-making competences of the Scottish Parliament. This article will examine the situation across the pond and invoke the jurisprudence of the Supreme Court of the United States in order to conclude that there is nothing unusual, or even sinister about the use of section 35 in this instance.
HEPATIC SUBCAPSULAR HEMATOMA FOLLOWING LAPAROSCOPIC CHOLECYSTECTOMY: A CASE REPORT
Authors:   Marly Clinic, Carolina Barrios Maria , Sotomayor Julian , Lozano Juan Mauricio , Pulido-Segura Jean
Published: December 2024

Key Words

Laparoscopic cholecystectomy, hepatic subcapsular hematoma, postoperative complication, endovascular embolization

Background

Hepatic subcapsular hematoma is a rare complication of laparoscopic cholecystectomy, with few cases reported in the literature. Injury to the liver parenchyma or liver capsule tears during gallbladder traction, anatomical variations in the hepatic vascular system and coagulopathy due to NSAIDS have all been proposed as possible associations.

Methods

We report a case of a 56-year-old female patient who developed a subcapsular hepatic hematoma after undergoing laparoscopic cholecystectomy, who was successfully treated by endovascular embolization.

Conclusion

Hepatic subcapsular hematoma is an infrequent complication of laparoscopic cholecystectomy that could be treated endovascularly.