bluuebunny/crossref_metadata_2025 huggingface dataset:
DESENVOLVIMENTO DE SISTEMA MÓVEL DE COLETA DE DADOS PARA CONSTRUÇÃO DE ZONAS CLIMÁTICAS LOCAIS
Authors: Engel Ernestina Rita Meira , Ozelame Ferrarez Gabrieli , Gonçalves Pedro Henrique
Published: September 2021

O estudo das variáveis climáticas assume importância no cenário atual, através das temáticas de desenvolvimento sustentável e smart cities, que se inserem nas discussões sobre planejamento urbano. O objetivo do estudo é criar um método de coleta de dados para o monitoramento do clima em Goiânia, baseado nas medições de temperatura e umidade, aliado a um sistema de mapeamento. Através da coleta, é possível determinar a existência de alterações no clima e fenômenos climáticos. Com uso de sensores e transectos urbanos, realizou-se o mapeamento da primeira etapa da pesquisa, para verificar as possibilidades de uso do sistema em estudos de classificação a partir da metodologia das Zonas Climáticas Locais, ferramenta auxiliar para a gestão de mudanças climáticas relacionadas à tecnologia de inovação. Como resultados, pode-se concluir que o método de coleta pode ser utilizado para esse os estudos, contribuindo para discussões sobre as alterações climáticas na escala local.
AVALIAÇÃO DA QUALIDADE DA ÁGUA PARA ABASTECIMENTO HUMANO DO ASSENTAMENTO 10 DE ABRIL, CRATO (CE) E SISTEMA INTEGRADO DE SANEAMENTO RURAL DA BACIA DO SALGADO
Authors: Costa Mariell Lima , Costa Junior Juscelino Martins , Vorpagel Jefferson Dos Santos , Zonin Wilson João
Published: September 2021

O Saneamento inclui atividades relacionadas ao tratamento de água e esgoto, coletas de lixo e práticas de higiene. A lei N° 11.445 de 2007 estabelece as diretrizes nacionais para o saneamento básico no País. No Estado do Ceará a Política Estadual para o Saneamento Rural, busca a universalização dos serviços de abastecimento de água e de esgotamento sanitário no meio rural e em comunidades urbanas e localidades de pequeno porte. O Sistema Integrado de Saneamento Rural do Ceará (SISAR/CE) foi criado em 1996, com o apoio da CAGECE, governo do Estado e do Banco Kfw. Surgiu como uma alternativa de gestão, através da necessidade da garantia que os sistemas de abastecimento de água de comunidades rurais, tivessem continuidade e qualidade ao longo do tempo. Logo o estudo tem como objetivo avaliar e discorrer sobre as condições da água para consumo humano que abastece o Assentamento 10 de abril, localizado no municipio de Crato – Ceará. Nessa perspectiva foi solicitado ao SISAR – BSA os laudos dos últimos três meses da água tratada e o laudo mais recente da água bruta das análises físico-químicas e microbiológicas de potabilidade, com a finalidade de observar se água que abastece a comunidade está dentro dos parâmetros e padrão de qualidade exigido pela legislação vigente. Pôde-se constar que a alternativa de gestão compartilhada entre comunidade e SISAR - BSA garante água tratada dentro dos padrões de potabilidade de água para consumo humano, possibilitando assim a melhoria da saúde e qualidade de vida da população abastecida.
On the Legal Regulation of Science
Authors: Shepelev Gennady
Published: September 2021

The analysis of legal documents in the field of science is carried out. The main areas of analysis include the following blocks: the subject of the scientific sector; the main participants in the process of production and consumption of scientific knowledge, their market and non-market relations; the management system of the scientific sector, including provision of the resources to the scientific sector. The analysis of the existing documents (laws, decrees of the President of the Russian Federation, resolutions of the Government of the Russian Federation, orders of ministries, etc.) was carried out for each of the selected blocks. The influence of the legal documents on the solution of certain issues of the organization of scientific activity is analyzed, and possible directions for improvement regulatory legal acts to optimize the functioning of the scientific sector are proposed.
Review of Regulatory Legal Acts in the Field of Science Regulation (01.01.2021 – 01.09.2021)
Authors: Serebriakov Andrei
Published: September 2021

Rule-making on the regulation of science is actively developing. Every year, the state authorities adopt an administrative number of acts regulating various aspects of the activities of the scientific community. Often, documents introduce editorial changes, but some of them contain new provisions that significantly change the life of a scientist. For this reason, it is important to always be aware of the current state of the regulatory legal framework on the regulation of science, to understand the agenda of this process. The review contains information on the main regulatory legal acts on the regulation of the scientific and technical sphere for eight months of 2021. The documents are divided into groups according to their legal force: federal laws; decrees of the President of the Russian Federation; acts of the Government of the Russian Federation; departmental regulations of the Ministry of Science and Higher Education of the Russian Federation; recommendations of the Presidium of the Higher Attestation Commission of the Ministry of Education and Science of Russia.
On the State of Innovative Activities of Small Enterprises in Russia
Authors: Skazochkin Aleksandr
Published: September 2021

The purpose of the article is to analyze some aspects of the state of innovation in Russia, including the state of small innovative business, venture capital financing startups, the dynamics of the creation of business entities by universities and research institutes. The facts of an extremely small number of small innovative enterprises created by universities and research institutes were recorded, as well as a low level of innovative activity of small enterprises over the entire period of statistical observations, a long-term dynamics of a decrease in the share of innovative goods, works and services in 2019 by almost two times (1.7 times) compared to 2013. The presented data indicate the low effectiveness of the idea of direct copying of the American model of technology commercialization, according to which the main player here should be higher educational institutions, as it has historically developed in the United States. It was concluded that in order to create an effective model of an innovation system consisting of proactive owners of research and development results, venture funds financing startups, universities that undertake the organization of research and development for the subsequent release of results to the market, large firms financing a significant percentage of turnover in R&D, in Russia there were no conditions and, unfortunately, until now there are none. The system needs to be corrected taking into account the real state of the Russian economy.The article analyzes several current competitions for the development of innovative activities held by large companies and administrations of Russian regions and makes proposals for correcting the organization of competitions.
The Foundation and the First Decades of the Activity of the St. Petersburg Academy of Sciences in the Works of Russian and Foreign Historians of Science. Part I.
Authors: Kupriyanov Viktor , Smagina Galina
Published: September 2021

The article is devoted to a critical review of historiography on the problem of the founding and the first decades of the activity of the St. Petersburg Academy of Sciences. The article covers the works of Russian historians of science written from the 18th century to the beginning of the XXIth centuries. The article gives an analysis of the early historiography of the history of the Academy of Sciences (the works of G. F. Miller, I. D. Schumacher), the works of historians of the XIX century (A. A. Kunik, P. P. Pekarsky and others), as well as the works of the Soviet historians of science. Highlighting the works by Yu. Kh. Kopelevich, the authors emphasize the importance of the Soviet historiography of the foundation of the Academy of Sciences. It is shown that Soviet researchers in many respects continue the approaches outlined in the pre-revolutionary period. The article shows that in the historiography of the XIX-XXth centuries emphasize the importance of nationality in understanding the history of the foundation of the Academy of Sciences. In the XIXth century, the idea of Russification of the Academy of Sciences was formed as a basis for the understanding its early history. In Soviet historiography, this idea further developed under the influence of the ideological campaigns of late Stalinist times, although it acquired distorted forms. The authors of the article show thatalthough the post-Soviet Russian historiography of the foundation of the Academy of Sciences continues the Soviet one, in many ways, it offers not only new approaches to understanding of the history of the foundation of the Academy of Sciences, but also new research topics. Research into the founding of the Academy of Sciences became more specialized.
How to Avoid Hijacked Journals? Recommendations for Journals and Authors
Authors: Abalkina Anna
Published: September 2021

This paper reviews the proliferation of hijacked journals in scientific communication. Hijacked journals mimic genuine journals, deceive potential authors, use more sophisticated methods of fraud and compromise the content and information of legitimate journals in international and national scientometric databases. The lists of hijacked journals are not replenished regularly and this creates a challenge to the international and Russian academic community. In order to warn authors and journals, this paper reviews the characteristics of hijacked journals and presents recommendations on how to avoid fake journals.
Adapting to Environmental Changes: the Risks of Social and Technological Innovations
Authors: Mozgovaya Alla
Published: September 2021

The initial methodological position mentioned in the article is the following statement: changes at any level contain a potential threat of damage — that is, a risk — and require developing a strategy for taking on these risks. The article expands on why scientific research is relevant, and speaks of how important it is for management practices to accumulate and generalize sociological knowledge about the social and personal determinants affecting how the population chooses its adaptation strategies in response to such changes in the institutional environment that violate their traditional way of life. The study object is the population, the subject — the main determinants that define how one adapts to the risks of environmental innovations.
Adaptation in the context of this article is interpreted by the author as the process of choosing and implementing a decision pertaining to the types of actions that ensure the subject’s minimal vulnerability when dealing with the risks of a changing living environment.
In order to identify the factors that influence choice of strategy for adapting to such environmental changes that may cause damage to a human being’s health and lifestyle, the projective situation method was used. Data from the 27th wave of RLMS–HSE was used as the empirical data base.
The author correlates the interpretation of empirical data with the resource approach, specifically with the idea of “total life resource” (N.F. Naumova). The goal is to identify the relationship between choosing a particular strategy for adapting to the risks of environmental innovations and individual elements and indicators of total life resource. Our analysis allowed for us to propose an expanded typology of strategies for forced adaptation to the risks of environmental changes, as well as to identify a number of factors that determine the choice.
Overall it can be argued that such a type of resource as one’s natural abilities seems to contribute to differentiation in the most significant way. If we look into individual factors, the following contribute to strategy differentiation: age, presence of and desire to achieve life goals, ability to adapt, emotional and psychological status, preferred method for solving problems, health, life satisfaction, gender, level of education, social status.
Chinese worldview research methodology
Authors:   Xi’an University of Foreign Studies, Dubkova Olga V. , Denisenko Anastasia V. ,   Peoples’ Friendship University of Russia
Published: September 2021

An analysis of modern studies of the Chinese worldview allows us to highlight the general positive and negative trends in modern sinology. The author notes the wide coverage of various fragments of the world’s picture, which allows creating a language base for modeling as well as identifies the main problems associated with the insufficient attention of researchers to the features of the Chinese language and Chinese culture.
Creativity of L.N. Andreev in the reception of D.V. Filosofov (based on the material of literary and critical articles 1907)
Authors:   Kostroma State University, Koptelova Natalya G.
Published: September 2021

The author examines the peculiarities of the reception of L.N. Andreev, reflected in the literary-critical articles of D.V. Filosofov, written in 1907. The features of his critical method are characterized. It is shown that the interpretation of Andreev’s works in these works of Filosofov was subordinated to the concept of building a “new religious consciousness”, developed by him together with his spiritual allies — D.S. Merezhkovsky and Z.N. Gippius. In 1907, the creative personality of Andreev was still characterized by Filosofov as a “background” figure, in comparison with the personality of Gorky and the cohort of realists united around the publishing house called “Knowledge”. The critic saw the damage to Andreev’s world outlook in the writer’s rejection of “culture”, “consciousness” and “religious community”. At the same time, he strenuously tried to “cut off” Andreev from the “philosophy” of Gorky and the realists of the Gorky circle. In addition, Andreev’s ideological and artistic quest was investigated by Filosofov in the context of such a complex literary phenomenon at the turn of the century as “mystical anarchism”. In general, the critical assessments of Andreev’s work presented in the articles of Filosofov in 1907 are ambiguous and dialectical. Revealing the “strength” and “weakness” of Andreev the artist, Filosofov in many ways showed himself as a critic and “educator”. He not only waged a struggle with Andreev, the singer of pessimism, despair and “nothingness”, but also tried to direct this talented writer along the “correct” ideological path, turn the vector of his creative movement towards “religious revival”, that is, “new Christianity”.
Mineração de dados na análise dos condicionantes dos movimentos de massa na região serrana do Rio de Janeiro
Authors: Souza Louis Felippe Gonçalves de , Francisco Cristiane Nunes
Published: September 2021

Os movimentos de massa são processos de evolução das encostas que têm como principais condicionantes os elementos físicos. No entanto, estudos sobre a análise espacial da fisiografia conjuntamente com as ocorrências requerem grande volume de dados. Neste sentido, técnicas automatizadas para descoberta de conhecimento podem auxiliar na realização destes estudos. Logo, o objetivo deste trabalho é a aplicação da mineração de dados na descoberta de conhecimento sobre os condicionantes fisiográficos dos movimentos de massa. A área de estudo é a região serrana fluminense onde ocorreu um dos maiores desastres naturais do Brasil em 2011. Foi aplicado o algoritmo Apriori que possibilitou a extração de regras de associação entre as 2,2 mil cicatrizes de movimentos de massa de 2011 e os condicionantes fisiográficos, constituídos pelo uso e cobertura da terra e as variáveis geomorfométricas. As regras revelaram que as cicatrizes prevaleciam em encostas convergentes e côncavas de relevo montanhoso, na faixa altimétrica entre 1.000 e 1.200 m, e cobertas por vegetação herbácea. Entre os condicionantes avaliados, destacou-se a curvatura das encostas, presente nas quinze regras de associação, possivelmente, devido as corridas de massa terem sido o tipo de movimento de massa de maior ocorrência no evento estudado. No entanto, nos condicionantes altimétricos e do uso e cobertura da terra, não houve prevalência expressiva das cicatrizes em nenhuma de suas classes, o que indica menor relevância. Conclui-se, assim, que provavelmente a combinação dos condicionantes geomorfométricos, declividade e curvatura, possibilitou a elevada magnitude dos eventos ocorridos na região serrana fluminense em 2011.
Drug Compatibility in Treatment of Chronic Infectious Diseases
Authors: Bazrova E. S. , Kaminskiy G. D. , Ilchenko L. Yu. , Маtin A. , Nikitin I. G.
Published: September 2021

The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpose is to substantiate the possibility and emphasize the relevance of the additional search of the creation of the most optimal combinations of drugs for long-term and massive pharmacotherapy, that could be due to a beneficial drug-drug interaction, optimization of the regimen, route of drug administration and multitarget of the therapeutic effect, reduce the pharmacological load while maintaining the effectiveness of the treatment, increase patient adherence to drug therapy.
An empirical investigation into organizational level antecedents of value co-destruction in Lisbon, Portugal: A hospitality sector case
Authors: Chuchu Tinashe , Nascimento Cunha Maria , Maziriri Eugine Tafadzwa
Published: September 2021

In recent years, scholars have begun to dedicate their attention to destructive relationships as a critical component of organizational life. Prior research has approached it from various points of view, such as trust and partnering, project management, and relational coordination. The purpose of this research is to explore organizational level antecedents of value co-destruction in Lisbon, Portugal within the hospitality sector. The research was quantitative in nature, adopting the survey method. To measure the proposed hypotheses, a unique conceptual model was developed with leadership support, supportive organizational climate, value co-destruction, and commitment to value co-creation as constructs. Data was collected from the hospitality sector of Lisbon, Portugal where 600 responses were obtained for analysis. All participants were employees from the hospitality sector. Key findings revealed that leadership support was dominant in comparison to the other constructs based on how high it loaded as a factor. In addition, a high perception of a supportive organizational climate among service employees will result in a low occurrence of value co-destruction in their organization. Further research direction on the subject is proposed.
Legal protection justice collaborators in corruption justice system
Authors: Ali Asgar Mochamad , Nurjaya I Nyoman , Sugiri Bambang , Anshari Tunggul
Published: September 2021

Corruption is a crime that is difficult to eradicate because the perpetrators of corruption usually have a strong economic and political position so that corruption is classified as a white-collar crime, crimes as business, economic crimes, official crime, and abuse of power. The purpose of this research is to know the urgency of providing legal protection for witnesses to perpetrators who are willing to cooperate with law enforcement in the investigation of Corruption Crimes. This research is normative legal research using the statute approach, philosophical approach, and case approach. The results can be explained that the urgency of providing legal protection for perpetrators of witnesses who are willing to cooperate with law enforcement in the investigation of Corruption Crimes because Justice Collaborator is the main actor who can help uncover a crime because it has the potential to have evidence to drag the main perpetrator and other suspects in. Third, the future arrangements for perpetrator witnesses who are willing to cooperate with law enforcement still cannot be used as a strong legal basis regarding the right of commutation of sentence for Justice Collaborators in criminal justice by law enforcement officers and many have weaknesses, especially in terms of commutation of sentences for Justice Collaborators for their testimonies in assisting law enforcement officers but are only used as considerations by judges without any binding power that obliges judges to provide leniency.
Investment climate for MSMEs towards a green economy
Authors: Suparji Suparji
Published: September 2021

Indonesia's development has not provided the optimum portion of the support to Micro, Small & Medium Enterprises (MSMEs), even though these MSMEs are the foundation of economic growth and as a supporter of the national economy of developing countries that are able to absorb up to 99% of the workforce, and are able to complement large industrial products in the local and local markets. The low government support makes MSMEs less empowered and less competitive in the global market. In this research problem, what is the role of Islamic economics and the green economy in increasing the capacity of MSMEs in order to advance the national economy? The limitation of the very cliche of MSMEs is the gap in accessing formal financial institutions in increasing capital, this is due to the weak management of MSMEs so that they are not bankable. Indonesia's financial inclusion as of 2019 was 76%, and 25% of it has not been served by formal financial services. This study uses a descriptive analysis approach, this study analyzes data obtained from secondary sources. The type of research used is based on a normative juridical approach. Normative juridical research is legal research that examines library data, including legal principles and legislation. According to the type of norm study research, data acquisition is sourced from literature research related to the problem being studied, such as books, laws, and others. The analytical method used is normative qualitative which examines and interprets and reconstructs the statements contained in the legislation. The theory used is the theory of people's welfare. The results of this study can be a recommendation and can be used by economic and financial policymakers in increasing the capacity of MSMEs based on sharia economics and making MSMEs the frontline in supporting national economic growth so that Indonesia advances without depending on foreign investment.
Public interaction of health workers during the Covid-19 pandemic
Authors: Pricilly Dea Tara Anglelorenza , Maharani Aliefya Rachim
Published: September 2021

The impact of the COVID-19 pandemic has limited the space for the community and health workers to provide health services. In this study, we want to see how the role of health workers can minimize health problems that occur in the field. GERMAS (Gerakan Masyarakat Hidup Sehat) which contains to implement the health service programs seeks to provide information through mobile broadcasts on services for preventing Covid-19 activities through vaccination and distributes anthelmintics to children, which is expected to be a forum for the health service to keep interacting with children and societies and also to give some meanings or messages to conveyed the community. This research used a qualitative descriptive method with case study methods and data collection techniques through interviews and observations. The theory used in this research is Coordinated Management of Meaning. For the results, Tanjung Selor Health Center Health Workers and the Tanjung Selor community set a pattern to create meaning in their communication. Health workers and communities create meaning and interpret meaning in their activities through the GERMAS Program.
El ciclismo femenino español en la década de 1890: salud, moda, amor y competición = Spanish women's cycling in the 1890s: Health, fashion, love and competition
Authors: Camino Alejandro
Published: September 2021

En la década de 1890, el ciclismo en España experimentó un fuerte auge, sobre todo en hombres, pero también en mujeres. En estos diez años, el ciclismo se desarrolló tanto en la vertiente de ocio como en la competitiva. En ambos casos se generó un enconado debate entre expertos, especialmente médicos, escritores y religiosos, y los propios aficionados al ciclismo, sobre la conveniencia (o no) de que las mujeres montasen en bicicleta. A los argumentos sobre la salud y la vestimenta, que habitualmente han centrado la atención historiográfica sobre el ciclismo femenino, pronto se sumaron aquellos que hacían referencia a la posibilidad de generar espacios de sociabilidad proclives al surgimiento del amor duradero. Un campo aparte fue el ciclismo de competición, que, si bien fue apoyado por los partidarios de la bicicleta, no terminó de cuajar entre la población y no hubo muchas mujeres que se dedicasen profesionalmente a este deporte. AbstractIn the 1890s, Spanish cycling experienced a great boom, especially in men, but also in women. In those years, cycling developed both as leisure and as competition. In both cases, there was a lively debate among experts, particularly physicians, writers and religious authorities, and cycling fans, about whether riding bicycles was a suitable activity for women (physically, psychologically and socially) as well as occurred in a transnational context. Most historians who address women’s cycling have focused on the arguments about health and clothing, but there also existed the question of cycling as a space for development of strong love relationships. Competitive cycling represents a very different case; although it was encouraged by bicycle supporters, it did not take hold among the population; and there were not many women who did this sport professionally. In this article I analyse these aspects through an in-depth study of journalistic sources. Besides, I use the most up-to-date and leading bibliographic contributions of national and international historiography.
A valorização do movimento no desenvolvimento de jogos eletrônicos = La valoración del movimiento en el desarrollo de juegos electrónicos = The valuation of movement in the development of electronic games
Authors: Silva Ana Paula Salles da , Inácio Humberto Luis de Deus , Gemente Flórence Rosana Faganello , Silva Ana Márcia
Published: September 2021

ResumoEsta pesquisa tem como objetivo investigar a trajetória da valorização do movimento no desenvolvimento de Jogos Eletrônicos desde a década de 70 até a atualidade. Trata-se de uma pesquisa documental que utilizou como fonte de dados o conteúdo de páginas eletrônicas de corporações comerciais, de sites de notícias de Jogos Eletrônicos e páginas online de jogadores. Os dados indicam que os Jogos Eletrônicos de Movimento lançados no mercado na última década reproduzem princípios de experiências realizadas em diferentes cenários, não sustentando o rótulo de inovação, sendo as principais diferenças a melhoria da qualidade dos acessórios, dos jogos e a minimização dos custos.ResumenEste estudio tiene como objetivo investigar la trayectoria de valoración  del movimiento en el desarrollo de juegos electrónicos desde la década de 1970 hasta la actualidad. Se trata de una investigación documental que utilizó como fuente de datos el contenido de sitios web de corporaciones comerciales, sitios de noticias de Juegos Electrónicos y páginas en línea de jugadores. Los datos indican que los Juegos Eletrócnico de Movimiento lanzados al mercado en la última década reproducen principios de experimentos llevados a cabo en diferentes escenarios, no sustentando la etiqueta de innovación, siendo las principales diferencias la mejora de la calidad de los accesorios, los juegos y la minimización de costos. AbstractThis research has objective to investigate the trajectory of the valorization of the movement in the development of Electronic Games since the 70's until today. It is a documentary research that used as a data source the content of electronic pages of commercial corporations, of news sites of Electronic Games and online pages of players. The data indicate that the Electronic Movement Games launched on the market in the last decade reproduce principles of experiences carried out in different scenarios, not sustaining the innovation label, the main differences being the improvement of the quality of the accessories, the games and the minimization of costs.
Postmodernizam, jezična politika i ratovanje na Bliskome istoku
Authors: Vrgoč Dalibor
Published: September 2021

Petnaest godina nakon Drugoga libanonskog rata – vođenoga 2006. između Države Izraela i Hezbolaha, militantne šijitske organizacije u Libanonu – analitičari su uglavnom jednodušni u ocjeni kako je Izrael u najmanju ruku doživio vojni neuspjeh u tome ratu. Premda danas s višegodišnjim odmakom ocjene ishoda rata nisu više toliko kategoričke i apsolutne, neki od čimbenika koji su utjecali na neuspješnost Izraelskih obrambenih snaga (DF) ipak su se pokazali relevantnima, a njihov odjek prepoznatljiv je i u aktualnoj izraelskoj vojnoj misli. Stoga je u ovome radu istraživački interes usmjeren na dosad nedovoljno proučavan aspekt Drugoga libanonskog rata – jezik. Pritom se tematizira terminologija koju su izraelske vojne snage rabile u ratnim operacijama protiv Hezbolaha. Prema izvješću izraelskoga povjerenstva ustrojenoga nakon završetka rata terminologija uvedena u vojne doktrine netom prije sukoba na više se mjesta izrijekom apostrofira kao jedna od determinanti izraelskoga vojnog neuspjeha. Istraživanjem primarnih izvora te sagledavanjem recentnih reevaluacija učinaka i ishoda rata osvjetljuju se razmjeri posljedica paušalnoga pristupa oblikovanju vojnojezične politike. Podrobnije se problematizira znanstvena težina koju terminologija nosi u jeziku svake struke, a posebice u vojno-obrambenim znanostima.
Management Efforts of Muhammadiyah Middle School Management in Sidoarjo in the Covid-19 Era
Authors: Yani Muhammad , Hanun Nur Ravita , Setiyono Wisnu Panggah
Published: September 2021

The assessment method used in this research is a qualitative approach. Data collection techniques used in this study were observation, interviews and FGD with ten informants, namely the Head of Muhammadiyah Middle School in Sidoarjo. The data analysis technique uses three steps in collecting research results, namely data reduction (data reduction), data presentation (data display), and drawing and testing conclusions or verification. The results of this study are as follows: The school anticipates students who do not have Learning From Home (BDR) support facilities, limited internet access and financial constraints by setting up tabs provided at school, these tabs can be used by students to do assignments. The strategies applied are very diverse, including: Allocating teacher supervision funds for other needs, providing motivation and stimulus so that teachers can deliver learning optimally, collaborating with filmmakers to make learning videos, holding MSG (Morning Spiritual Gathering) activities or referred to as Ngaji, Briefing, and Berinfaq, while also seeking donations for students to pay tuition fees. Implementation of short-term and long-term plans: looking for a learning format that can be maximized, trying to foster parental trust in the school, trying to build communication with students and parents through activities that support education, collaborating with parents so as to foster an understanding that shared responsibility, focus on learning that is important for students' self-development, and improve the technological capabilities of students and teachers to be able to innovate in each other's learning.
PALEOENVIRONMENTAL IMPLICATIONS OF INVERTEBRATE FECAL PELLETS (EDAPHICHNIUMISP.) AT AN ICHNOFOSSIL-RICH DINOSAUR NESTING LOCALITY, UPPER CRETACEOUS TWO MEDICINE FORMATION, MONTANA, USA
Authors: FREIMUTH WILLIAM J. , VARRICCHIO DAVID J. , CHIN KAREN
Published: September 2021

The terrestrial feeding trace Edaphichnium lumbricatum is known from the Triassic to the Pleistocene and is characterized by tubular burrows with ellipsoidal fecal pellets, indicating substrate feeding by earthworms or other invertebrates. We describe 11 specimens attributable to Edaphichnium isp. from Egg Mountain, a terrestrial locality with a diverse fossil assemblage from the Upper Cretaceous Two Medicine Formation in Montana, USA, and assess their paleoenvironmental and paleoecological implications. These ichnofossils were recovered from a 1.5 meter stratigraphic succession comprised of calcareous siltstones and limestones with abundant fossil insect pupal cases, representing well-drained paleosols. Although burrows are not always present, three recurring arrangements of Edaphichnium isp. fecal pellets are identified: linearly arranged pellets, horizon-confined pellets, and pellets in clusters dispersed vertically and horizontally throughout the matrix. Two color patterns (light and dark pellets) are also distinguished. Pellets are fine-grained and have a consistently ellipsoidal shape (length:diameter of 1.57), with maximum lengths ranging from 1.9–6.7 mm (mean 4.1 mm) and maximum diameters ranging from 1.0–4.1 mm (mean 2.6 mm). Geochemical analyses indicate pellets are comprised of varying proportions of calcite, plagioclase, and quartz, and are enriched in phosphorus relative to the sedimentary host matrix. Possible trace makers include chafer or other coleopteran larvae, millipedes, and earthworms, suggesting a range of capable trace makers of Edaphichnium-like fecal pellets. Edaphichnium isp. at specific stratigraphic horizons suggests increased organic content in the subsurface, potentially connected to depositional hiatuses. Edaphichnium isp. adds a secondary component to the Celliforma ichnofacies known from Egg Mountain and surrounding strata, and to the array of nesting, feeding, and dwelling traces of wasps, beetles, other invertebrates, mammals, and dinosaurs from the locality.
Judicialização do cinacalcete no estado do Rio de Janeiro
Authors: Mota Karla
Published: September 2021

Objetivo: Analisar a judicialização do cinacalcete no estado do Rio de Janeiro e estimar o seu impacto no orçamento do estado do Rio de Janeiro no ano de 2015. Métodos: Estudo transversal descritivo que analisou os pareceres técnicos emitidos pelo Núcleo de Assessoria Técnica em Ações de Saúde do Tribunal de Justiça do Rio de Janeiro entre 2009 e 2016. Realizou-se uma busca no banco de licitações da Secretaria de Estado de Saúde do Rio de Janeiro para encontrar o valor pago por esse medicamento em 2015. Resultados: Entre 2009 e 2015, esse núcleo elaborou 23.852 pareceres, com 1.553 relacionados ao cinacalcete, sendo 359 em 2015. Entre os autores, 88% residiam na capital deste estado, 50,4% eram mulheres, 46% tinham renda entre 1 e 3 salários mínimos. A decisão judicial foi favorável ao autor em 100% dos processos. Conclusão: Em 2015, foram gastos cerca de 3,7 milhões de reais para compra desse medicamento, o que equivale a 2,5% dos recursos destinados à assistência farmacêutica do estado do Rio de Janeiro neste ano, caracterizando um elevado impacto no orçamento da saúde.
Isotope-Geochemical Features of Apoultrabasic Metasomatites of the Sayan–Baikal Folded Area
Authors: Rampilova M.V. , Ripp G.S. , Rampilov M.O. , Damdinov B.B. , Damdinova L.B. , Posokhov V.F.
Published: September 2021

—The paper is concerned with a geochemical study of apoultrabasic metasomatites of the Ospa–Kitoi, Parama, and Ust’-Kelyana ophiolite massifs located in the southern folded framing of the Siberian craton. The isotope (O, C, H, Sr, and Rb) systems of dunites, serpentinites, nephrites, listvenites, and talc–carbonate rocks are studied. The isotopic composition of oxygen in olivines from dunites is characterized by δ18O = 4.6–5.5‰. The δ18O values of serpentinites (4.67–7.35‰) point to the mantle genesis of fluids and might have been inherited from ultrabasic rocks. Nephrites are slightly enriched in heavy oxygen isotope (δ18O = 6.13–9.54‰). This indicates that their fluid phase was transported from serpentinites and captured a small portion of the crustal component. The widest variations in δ18O values, from 8.12 to 17.46‰, are observed in minerals from listvenites. Carbonates from these rocks show a highly heterogeneous isotopic composition of oxygen (δ18O = 12.9–18.8‰) and carbon δ13C = –2.8 to +2.8‰). These rocks formed with the contribution of metamorphogenic fluids. According to the isotopic composition of hydrogen, the examined serpentinites are divided into two groups: with δD values specific to “magmatic water” (δD = –73.50 to –85.00‰) and those typical of meteoric fluids (δD = –151.90 to –167.20‰). The listvenites are characterized by low Rb and high Sr contents. Their 87Sr/86Sr values (0.70702–0.70971) indicate the contribution of a crustal source. The study of fluid inclusions in minerals from listvenites has shown that the rocks formed under relatively low-temperature conditions. The homogenization temperatures of fluid inclusions in quartz and magnesite from listvenites of the Ospa–Kitoi massif are 184–290 ºC and 122–182 ºC, respectively. In the Parama massif, the homogenization temperature of fluid inclusions in quartz is 130–170 ºC. The solutions that formed listvenites of the Ospa–Kitoi massif were slightly saline (TDS = 2.9–8.4 wt.% NaCl eq.), with NaCl and Na2CO3 being the main salt components.
Aedes Fluviatilis Cell Lines As New Tools To Study Metabolic And Immune Interactions In Mosquito-Wolbachia Symbiosis
Authors: Conceição Christiano Calixto , Silva Jhenifer Nascimento da , Arcanjo Angélica , Nogueira Cíntia Lopes , de Abreu Leonardo Araujo , de Oliveira Pedro Lagerblad , Gondim Katia C. , Moraes Bruno , de Carvalho Stephanie Serafim , Silva Renato Martins da , Vaz Itabajara da Silva , Moreira Luciano Andrade , Logullo Carlos
Published: September 2021

In the present work, we established two novel embryonic cell lines from the mosquito Aedes fluviatilis containing or not the naturally occurring symbiont bacteria Wolbachia, which were called wAflu1 and Aflu2, respectively. We also obtained wAflu1 without Wolbachia after tetracycline treatment, named wAflu1.tet. Morphofunctional characterization was performed to help elucidate the symbiont-host interaction in the context of energy metabolism regulation and molecular mechanisms of the immune responses involved. The presence of Wolbachia pipientis improves energy performance in A. fluviatilis cells; it affects the regulation of key energy sources such as lipids, proteins, and carbohydrates, increasing the speed of cell proliferation, making the distribution of actin more peripheral and with more extensions that come into contact with neighboring cells. Additionally, innate immunity mechanisms were activated, showing that the wAflu1 and wAflu1.tet cells are responsive after the stimulus using Gran negative bacteria. Therefore, this work confirms the natural, mutually co-regulating symbiotic relationship between W. pipientis and A. fluviatilis, modulating the host metabolism and immune pathway activation. The results presented here add important resources to the current knowledge of Wolbachia-arthropod interactions.
Controllability of Nonlinear Deterministic Chaotic Systems with Control-Induced Delay
Authors: Kumar Suman
Published: September 2021

This paper presents the analysis of a class of retarded nonlinear chaotic systems with control-induced delay. The existence and uniqueness of the mild solution are obtained by using the local Lipschitz condition on nonlinearity and Banach contraction principle. The approximate controllability for linear and nonlinear control delay systems has been established by sequence method and using the Nemytskii operator. The application of results is explained through an example of a parabolic partial differential equation.
Deep Transfer Learning Based Human Activity Recognition By Transforming IMU Data To Image Domain Using Novel Activity Image Creation Method
Authors: B.A Mohammed hashim , R Amutha
Published: September 2021

Human Activity Recognition is the most popular research area in the pervasive computing field in recent years. Sensor data plays a vital role in identifying several human actions. Convolutional Neural Networks (CNNs) have now become the most recent technique in the computer vision phenomenon, but still it is premature to use CNN for sensor data, particularly in ubiquitous and wearable computing. In this paper, we have proposed the idea of transforming the raw accelerometer and gyroscope sensor data to the visual domain by using our novel activity image creation method (NAICM). Pre-trained CNN (AlexNet) has been used on the converted image domain information. The proposed method is evaluated on several online available human activity recognition dataset. The results show that the proposed novel activity image creation method (NAICM) has successfully created the activity images with a classification accuracy of 98.36% using pre trained CNN.
Stimulated Phosphorylation of ERK in Mouse Kidney Mesangial Cells is Dependent Upon Expression of Cav3.1
Authors: Pandi Sudha Priya Soundara , Shattock Michael J. , Hendry Bruce M. , Sharpe Claire C.
Published: September 2021

Background: T-type calcium channels (TTCC) are low voltage activated channels that are widely expressed in the heart, smooth muscle and neurons. They are known to impact on cell cycle progression in cancer and smooth muscle cells and more recently, have been implicated in rat and human mesangial cell proliferation. The aim of this study was to investigate the roles of the different isoforms of TTCC in mouse mesangial cells to establish which may be the best therapeutic target for treating mesangioproliferative kidney diseases.Methods: In this study, we generated single and double knockout (SKO and DKO) clones of the TTCC isoforms CaV3.1 and CaV3.2 in mouse mesangial cells using CRISPR-cas9 gene editing. The downstream signals linked to this channel activity were studied by ERK1/2 phosphorylation assays in serum, PDGF and TGF-β1 stimulated cells. We also examined their proliferative responses in the presence of the TTCC inhibitors mibefradil and TH1177. Results: We demonstrate a complete loss of ERK1/2 phosphorylation in response to multiple stimuli (serum, PDGF, TGF-β1) in CaV3.1 SKO clone, whereas the CaV3.2 SKO clone retained these phospho-ERK1/2 responses. Stimulated cell proliferation was not profoundly impacted in either SKO clone and both clones remained sensitive to non-selective TTCC blockers, suggesting a role for more than one TTCC isoform in cell cycle progression. Deletion of both the isoforms resulted in cell death. Conclusion: This study confirms that TTCC are expressed in mouse mesangial cells and that they play a role in cell proliferation. Whereas the CaV3.1 isoform is required for stimulated phosphorylation of ERK1/2, the Ca V3.2 isoform is not. Our data also suggest that neither isoform is necessary for cell proliferation and that the anti-proliferative effects of mibefradil and TH1177 are not isoform-specific. These findings are consistent with data from in vivo rat mesangial proliferation Thy1 models and support the future use of genetic mouse models to test the therapeutic actions of TTCC inhibitors.
Analysis of the Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Breast Cancer Patients Treated With Cyclin-Dependent Kinases 4 and 6 Inhibitors (CDKi): Limited T-Cell Immunity Despite Satisfactory Humoral Response.
Authors: Saavedra Cristina , Vallejo Alejandro , Longo Federico , Serrano Juan José , Fernández María , Gion Maria , López-Miranda Elena , Martinez-Jañez Noelia , Guerra Eva , Chamorro Jesús , Rosero Diana , Velasco Héctor , Martin Adrian , Carrato Alfredo , Casado Jose Luis , Cortes Alfonso
Published: September 2021

SARS-CoV-2 vaccination in cancer patients has become crucial because of their higher risk of complications and death from COVID19. We performed a prospective study to assess the immunogenicity of SARS-CoV-2 vaccine in cancer patients treated with CDKi and compared their immune response with patients treated with chemotherapy. While a robust humoral response was observed in the CDKi patients compared with chemotherapy patients, limited T-cell immunity was achieved in both groups.
High-accuracy Photonics-assisted Frequency Measurement With Rough-accurate Compensation Based on Mach-Zehnder Interfering and Power Cancellation
Authors: Huang Lanfeng , Li Yongjun , Zhao Shanghong , Lin Tao , Wang Guodong , Li Xuan , Zhu Zihang
Published: September 2021

A high-accuracy photonics-assisted frequency measurement with rough-accurate compensation based on Mach-Zehnder interfering and power cancellation is proposed. A polarization division multiplexing dual-parallel Mach–Zehnder modulator (PDM-DPMZM) is employed to mix the unknown RF signal and sweep signal to optical field. The rough measurement is firstly performed by the interference of a Mach-Zehnder interferometer (MZI) to realize fast frequency estimation. Then, based on the rough measurement result, the accurate measurement based on power cancellation is implemented in a much narrower range, which greatly improves the efficiency of frequency measurement. The simulation results show that the amplitude comparison function (ACF) established by interference can achieve a measurement error of less than 0.3 GHz over 0.5 ~39 GHz. Moreover, thanks to the rough-accurate compensation, the accuracy can be further improved to 4 MHz. Additionally, the multiple frequency identification with a resolution of 10 MHz can also be achieved based on this system.
Integrated Pan-Cancer Analysis Reveals Distinct Clinical, Genomic and Immunological Features of the LILRB Immune Checkpoint Family in Acute Myeloid Leukemia
Authors: Xu Zi-jun , Zhang Xin-long , Jin Ye , Wang Shi-sen , Gu Yu , Ma Ji-chun , Wen Xiang-mei , Leng Jia-yan , Mao Zhen-wei , Lin Jiang , Qian Jun
Published: September 2021

Background

Leukocyte immunoglobulin (Ig)-like receptor Bs (LILRBs), a family of type I transmembrane glycoproteins, are known to inhibit immune activation.
Methods

We comprehensively evaluated the transcriptional levels and prognostic significances of LILRB members in a broad spectrum of cancer types, focusing on its role in AML. In addition, we systematically characterized the genomic and immune landscape in AML patients with altered LILRBs expression.
Results

Here, we show that LILRBs were significantly dysregulated in a number of cancers, especially in acute myeloid leukemia (AML). Clinically, high expression of LILRB1-LILRB4 predicted poor survival in six independent AML cohorts. Genetically, LILRB1 was associated with more mutational events than other LILRB members, and multiple genes involving in immune activation were deleted in LILRB1-high patients. Epigenetically, LILRB4 was significantly hypomethylated and marked by MLL-associated histone modifications in AML. Immunologically, LILRBs were positively associated with monocytic cells including M2 macrophages, but were negatively associated with tumor-suppressive CD8 T cells.
Conclusions

Our findings reveal critical immunological and clinical implications of LILRBs in AML, and indicate that LILRBs may represent promising targets for immunotherapy of AML.