bluuebunny/crossref_metadata_2025 huggingface dataset:
Effectiveness of red alga Asparagopsis taxiformis extracts against Leishmania infantum
Authors: Vitale Fabrizio , Genovese Giuseppa , Bruno Federica , Castelli Germano , Piazza Maria , Migliazzo Antonella , Minicante Simona Armeli , Manghisi Antonio , Morabito Marina
Published: October 2015

Leishmaniasis is a disease with a worldwide
distribution affecting both humans and animals. There is
a need to identify and develop new drugs for the treatment
of leishmaniasis. This study showed that crude ethanolic
extracts of the red alga Asparagopsis taxiformis have a
powerful effect against L. infantum, the prevalent species
of the genus Leishmania in the Mediterranean basin. L.
infantum demonstrated decreased vitality with increasing
concentration of the algal extracts. At a concentration of
40 μg/mL, the extracts achieved 100% mortality of the
parasite and the LD50 value was 25 μg/mL for promastigotes
and 9 μg/mL for amastigotes. Algal extracts caused
morphological alterations and apoptosis in Leishmania
cells. The potential cytotoxic action of crude extracts was
investigated by a MTT viability assay on DH82 and Vero
cell lines but there was no cytotoxic effect. The potential
of red alga A. taxiformis metabolites as anti-leishmanial
agents merits further pharmacological investigation.
How do gerunds conceptualize events? A diachronic study
Authors: Fonteyn Lauren , Heyvaert Liesbet , Maekelberghe Charlotte
Published: October 2015

This article offers a cognitive perspective on the evolution of the semantics of English nominal gerunds (NG) (I regret the signing of the contract) and verbal gerunds (VG) (I regret signing the contract). While the formal differences between NGs and VGs are well documented, their semantics remains largely unexplored territory. The perspective that is taken here is centered on the linguistic notion of reference and various aspects of the conceptualization involved in it. As they formally hover between more nominal and more clause-like internal properties, gerunds form an interesting test case for the cognitive perspective on referentiality. Our corpus analysis describes how the situations that NGs and VGs refer to are conceptualized as deictic expressions grounded in the speech event in Present-day English, and how this has changed since the Early Modern period. It is shown that only a multi-layered model of referentiality can account for the subtle differences found between NGs and VGs: while no fundamental shifts are found with regard to the traditional referential subtypes (specific, non-specific, generic), NGs and VGs do turn out to differ in their choice for either nominal or clausal grounding mechanisms, in their status as existentially stable or flexible entities and in the mental spaces in which they situate the events that they conceptualize.
Pharmacogenetics of healthy volunteers in Puerto Rico
Authors: Claudio-Campos Karla , Orengo-Mercado Carmelo , Renta Jessicca Y. , Peguero Muriel , García Ricardo , Hernández Gabriel , Corey Susan , Cadilla Carmen L. , Duconge Jorge
Published: October 2015

Puerto Ricans are a unique Hispanic population with European, Native American (Taino), and higher West African ancestral contributions than other non-Caribbean Hispanics. In admixed populations, such as Puerto Ricans, genetic variants can be found at different frequencies when compared to parental populations and uniquely combined and distributed. Therefore, in this review, we aimed to collect data from studies conducted in healthy Puerto Ricans and to report the frequencies of genetic polymorphisms with major relevance in drug response. Filtering for healthy volunteers or individuals, we performed a search of pharmacogenetic studies in academic literature databases without limiting the period of the results. The search was limited to Puerto Ricans living in the island, excluding those studies performed in mainland (United States). We found that the genetic markers impacting pharmacological therapy in the areas of cardiovascular, oncology, and neurology are the most frequently investigated. Coincidently, the top causes of mortality in the island are cardiovascular diseases, cancer, diabetes, Alzheimer’s disease, and stroke. In addition, polymorphisms in genes that encode for members of the CYP450 family (CYP2C9, CYP2C19, and CYP2D6) are also available due to their relevance in the metabolism of drugs. The complex genetic background of Puerto Ricans is responsible for the divergence in the reported allele frequencies when compared to parental populations (Africans, East Asians, and Europeans). The importance of reporting the findings of pharmacogenetic studies conducted in Puerto Ricans is to identify genetic variants with potential utility among this genetically complex population and eventually move forward the adoption of personalized medicine in the island.
The influence of selected design and operating parameters on
the dynamics of the steam micro-turbine
Authors: Żywica Grzegorz , Kiciński Jan
Published: October 2015

The topic of the article is the analysis of the
influence of selected design parameters and operating
conditions on the radial steam micro-turbine, which was
adapted to operate with low-boiling agent in the Organic
Rankine Cycle (ORC). In the following parts of this article
the results of the thermal load analysis, the residual
unbalance and the stiffness of bearing supports are discussed.
Advanced computational methods and numerical
models have been used. Computational analysis showed
that the steam micro-turbine is characterized by very good
dynamic properties and is resistant to extreme operating
conditions. The prototype of micro-turbine has passed a
series of test calculations. It has been found that it can be
subjected to experimental research in the micro combined
heat and power system.
CFD analysis of fluid flow in an axial multi-stage partial-admission ORC turbine
Authors: Surwilo Jan , Lampart Piotr , Szymaniak Mariusz
Published: October 2015

Basic operational advantages of the Organic Rankine Cycle (ORC) systems and specific issues of turbines working in these systems are discussed. The strategy for CFD simulation of the considered ORC turbine and the main issues of the numerical model are presented. The method of constructing the 3D CAD geometry as well as discretisation of the flow domain are also shown. Main features of partial admission flow in the multi-stage axial turbine are discussed. The influence of partial admission on the working conditions of the subsequent stage supplied at the full circumference is also described.
Designing and updating the flow part of axial and radial-axial turbines through mathematical modeling
Authors: Rusanov Andrey , Rusanov Roman , Lampart Piotr
Published: October 2015

The paper describes an algorithm for the design of axial and radial-axial type turbines. The algorithm is based on using mathematical models of various levels of complexity – from 1D to 3D. Flow path geometry is described by means of analytical methods of profiling using a limited number of parameters. 3D turbulent flow model is realised in the program complex IPMFlow, developed based on the earlier codes FlowER and FlowER-U. Examples of developed or modernized turbines for differentpurpose power machines are presented. They are: an expansion turbine, ORC turbine and cogeneration mediumpressure turbine.
De novo ceramide synthesis is involved in acute inflammation during labor
Authors: Signorelli Paola , Avagliano Laura , Reforgiato Marta R. , Toppi Nadia , Casas Josefina , Fabriàs Gemma , Marconi Anna Maria , Ghidoni Riccardo , Caretti Anna
Published: October 2015

Gestation is regulated by an inflammatory process that allows implantation and parturition. The comprehension of such inflammatory switches is important for the identification of therapeutic targets in pregnancy defects. Sphingolipids are a class of structural membrane components with important signaling functions. Among sphingolipids, ceramide is a well-known mediator of stress signals and pro-inflammatory responses. In this paper, we evaluated the association between ceramide increase and the inflammatory process of labor, comparing placentas from vaginal deliveries, including both spontaneous and induced labor, versus elective cesarean. We demonstrated that: (i) the inflammatory marker IL-6 is upregulated in labored placentas; (ii) IL-6 content inversely correlates with labor duration; (iii) ceramide content and expression of serine palmitoyl transferase (SPT, rate limiting enzyme for de novo ceramide synthesis) are increased in labored placentas; (iv) the expression of SPT directly correlates with inflammation and inversely with labor duration. These observations suggest that ceramide metabolism and signaling may be implicated in controlling important inflammatory mechanisms driving gestation: we hypothesize that ceramide can be a therapeutic target in inflammatory complications of parturition.
Effect of Nitrogen Content and Cooling Rate on Transformation Characteristics and Mechanical Properties for 600 MPa High Strength Rebar
Authors: Zhang Jing , Wang Fu-ming , Li Chang-rong , Yang Zhan-bing
Published: October 2015

To obtain appropriate chemical composition and thermo-mechanical schedules for processing the V-N microalloyed 600 MPa grade high strength rebar, the microstructure analysis during dynamic continuous cooling and tensile tests of three experimental steels with different nitrogen contents were conducted. The results show that increasing nitrogen content promotes ferrite transformation and broadens the bainite transformation interval, when the nitrogen content is in the range of 0.019–0.034 mass%. Meanwhile, the martensite start temperatures decrease and the minimal cooling rate to form martensite increases. To achieve a good combination of strength and ductility, the cooling rates should be controlled in the range of 0.5–3°C/s, leading to the microstructure of ferrite, pearlite and less than 10% bainite (volume fraction). Furthermore, all the experimental steels satisfy the performance requirement of 600 MPa grade rebar and the rebar with nitrogen content of 0.034 mass% shows the highest strength through systematically comparative investigation.
Characterization of Pyrolysis Products Obtained from Desmodesmus sp. Cultivated in Anaerobic Digested Effluents (DADE)
Authors: Li Gang , Dong Ren-jie , Fu Nan , Zhou Yu-guang , Li Dong , Chen Xiao Dong
Published: October 2015

The present study includes the compositional analysis and pyrolysis products obtained from Desmodesmus sp. cultivated in anaerobic digested effluents (DADE) from 300°C to 800°C. Compared to Desmodesmus sp. cultivated in BG11 (DBG11), both species exhibited a hydrogen content of ca. 6%, ca. 7% of nitrogen, and ca. 0.56% of sulfur except carbon content, of which was lower than DBG11. Pyrolysis products of DADE consisted of aliphatic hydrocarbons, aromatic hydrocarbons, acids, nitrogen compounds, phenols, polycyclic aromatic hydrocarbons (PAHs), alcohols, aldehydes, and furans. Pyrolysis of DADE at 800°C produced 62.52% (the maximum yield) of pyrolysis products compared to 41.89% at 600°C. Considering the reasonably high yield and minimum release of pollutants, lower temperature (600°C) was found to be optimum for producing biofuel from DADE. A process combing anaerobic digestion and algae cultivation can be proposed as a direct and effective way to produce biofuel so as to reduce contaminations to the environment.
Analogs of the Green and Puig correspondences for twisted group algebras
Authors: Harris Morton E.
Published: October 2015

In the modular representation theory of finite groups, we show that
the standard derivation of the Green
correspondence lifts to a derivation
of a Green correspondence for twisted
group algebras (Theorem 1.3). Then, from these results
we derive a lift of the Puig correspondences
for twisted group algebras (Theorem 1.6).

Clearly twisted group algebras arise
naturally in finite group modular representation theory. We conclude
with some suggestions for applications
in this mathematical area.
Bad Art, Quirky Modernism
Authors: Monks Aoife
Published: October 2015

This essay considers the systems of value that undergird the employment of quirky objects in scholarship and argues that quirk historicism is another iteration of modernism in its attachment to estrangement and theatricality as modes of critique. In doing so, the essay asks why it is that “bad art” is so much easier to co-opt into scholarship when it’s safely in the past.
Pigeons
Authors: Piekut Benjamin
Published: October 2015

The author shares his experience researching an elusive piece of music, reflecting on the possible causes of quirk historicism and the possible consequences of the postcritical turn.
Musicology in the Garden
Authors: Dolan Emily I.
Published: October 2015

This essay reflects on the role of aesthetics in the birth of musicology and asks to what extent musicology’s turn to materiality, via the work of Bruno Latour, might become a return to the discipline’s foundational principles.
Resultados clínicos y funcionales en reconstrucciones con aloinjertos intercalares de tibia
Authors: López Millán Lucas , Aponte Tinao Luis , Farfalli Germán L , Ayerza Miguel A , Muscolo D Luis
Published: October 2015

Resumen

Introducción: El objetivo de éste trabajo fue evaluar la sobrevida, complicaciones y resultados funcionales en un grupo de pacientes tratados con un aloinjerto intercalar de tibia luego de la resección tumoral primaria.

Material y métodos: Se evaluaron  26 tratados con aloinjertos intercalares de tibia luego de un defecto óseo secundario a una resección tumoral primaria. El seguimiento promedio fue de 6 años. La supervivencia del aloinjerto fue determinada por el método de Kaplan –Meier.  La evaluación funcional fue realizada con la escala de la Musculoskeletal Tumor Society (MSTS). También fueron registradas las complicaciones.

Resultados: La sobrevida global de las reconstrucciones fue del 84% (CI 95%: 90%-70%) a los 5 años y 79%  a los 10 años (CI 95%: 95%-63%). El aloinjerto debió ser removido en 5  pacientes, en 3 casos debido a infección y en 2 casos por recurrencia local. Dos pacientes presentaron falta de consolidación diafisaria y 3 pacientes presentaron una fractura incompleta. En ninguno  de estos pacientes el aloinjerto debió ser removido.  El resultado funcional promedio fue  de 27 puntos con un rango de 27 a 30 puntos.  Esto corresponde a un miembro funcional con capacidad funcional aceptable y sin dolor limitante.

Conclusiones: A pesar de la incidencia de complicaciones, éste análisis demostró una sobrevida aceptable con excelentes resultados funcionales. La reconstrucción con aloinjerto intercalar de tibia permite restaurar la anatomía de la pierna proporcionando buenos resultados clínicos y funcionales.
Osteosíntesis con tornillos canulados en fracturas mediales de cadera. Factores pronósticos y resultados en 93 casos
Authors: Pereira Sebastián , Calvo Ximena , Lugones Alfonso , Vindver Gabriel , Bidolegui Fernando
Published: October 2015

Re­su­men
 In­tro­duc­ción: La reducción y osteosíntesis con tornillos canulados en las fracturas mediales de cadera constituye una opción terapéutica válida. nuestro objetivo es identificar factores pronósticos y grupos de riesgo.

Materiales­ y­ Métodos: Se estudiaron retrospectivamente 93 fracturas intracapsulares de cadera tratadas con fijación interna con tornillos canulados de 6,5 mm, entre junio de 1995 y marzo de 2011 (71 no desplazadas y 22 desplazadas).

Resultados: En 82 de los 93 casos, se observó la consolidación de la fractura. Once pacientes tuvieron complicaciones (5 seudoartrosis y 6 necrosis avascular). En el grupo de fracturas no desplazadas, la consolidación fue del 95,8% y, en el grupo de las desplazadas, del 63,6%. en este último grupo, si presentaban conminución, la consolidación fue del 50% y, en el grupo sin conminución, fue del 71,4%. El índice de consolidación fue del 46,1% con reducción cerrada y del 88% con reducción abierta.

Conclusión:­La reducción cerrada y la osteosíntesis con tornillos canulados en fracturas impactadas o no desplazadas del cuello del fémur, cualquiera sea la edad del paciente, resulta un método exitoso. En las fracturas desplazadas, en cambio, la consolidación sin necrosis es menos previsible, por lo que su indicación deberá ser más meditada.

 

 
Lesiones del nervio torácico largo de Bell. Revisión de conceptos terapéuticos
Authors: Valbuena Sebastián E.
Published: October 2015

Re­su­men

las lesiones del nervio torácico producen parálisis del serrato anterior y originan una deformidad característica (escápula alata), que genera debilidad y alteraciones importantes en la movilidad del hombro. En esta revisión, se analizan conceptos sobre anatomía, etiología, presentación clínica y alternativas terapéuticas.

Long­ thoracic ­nerve ­of ­Bell. ­Review­ of­ therapeutic ­management

Abstract

The long thoracic nerve injuries are manifested by a characteristic deformity called scapula alata, causing weakness, and impaired shoulder mobility. in this review current concepts of the anatomy, etiology, clinical presentation and therapeutic management are analyzed.
Comparación entre la cirugía abierta y el método mínimamente invasivo para roturas agudas del tendón de Aquiles. [Comparison between open surgery and the minimally invasive method for acute Achilles tendon ruptures.]
Authors: Arzac Ulla Ignacio Ricardo , De Silvestri Adrian , Fiorentini Gustavo
Published: October 2015

Introducción. La reparación quirúrgica puede realizarse mediante cirugía abierta o por técnicas mínimamente invasivas. La técnica percutánea combina las ventajas del tratamiento quirúrgico abierto con el tratamiento ortopédico. El objetivo de este trabajo es comparar la técnica mínimamente invasiva de Dresden descripto por Amlang con la cirugía abierta convencional.

Material y métodos. Estudio comparativo de 15 casos de roturas de tendón de Aquiles operados con técnica abierta convencional y 15 casos operados con la técnica percutánea de Dresden. Se evaluaron características del intraoperatorio y hospitalización, resultados funcionales de acuerdo a score AOFAS, ARPS (achilles ruptura performance score), escala visual análoga y rango de movilidad de tobillo.

Resultados. Se mencionan los resultados comparativos del tiempo quirúrgico, trofismo, longitud de cicatriz, diferencia comparativa en el perímetro del gemelo. El AOFAS a 5 meses: Grupo A: 90 puntos, y grupo B: 95 puntos. Retorno a la actividad laboral: Grupo A, 7 meses promedio, Grupo B: 3,53 meses promedio. Retorno a actividad deportiva: en el grupo A: media 12,22 meses; Grupo B: media 6,53 meses.

Conclusión: La reparación percutánea de Dresden, es una buena opción para las roturas de tendón de Aquiles; con buena evolución clínico-funcional minimizando los riesgos de re rotura y lesiones del nervio sural. 
Combinación de taping con Escuela de Columna en pacientes con lumbalgia crónica: ensayo clínico controlado aleatorizado. [Combination of taping with Back School in patients with chronic low back pain: a randomized controlled clinical trial.]
Authors: Tana Andres , Matesa Maria Amelia , Catini Maria Eugenia , Ruiz Vanesa , Laiz Marisol , Gomez Ramiro , Peker Guillermo , Quiroga Cecilia , Reinoso Mayra , Ormaechea Valeria , Abadie Marianela , Di Gresia Fernanda Gabriela , Nadur Juan , Fournery Carolina , Bigatti Laura , Gomez Julieta Paula , Perez Cabrera Sabrina
Published: October 2015

Introducción: El 70-85% de la población general sufre dolor lumbar. Los programas de Escuela de Columna (EC) han demostrado ser efectivos en el tratamiento de la lumbalgia crónica (LC). El taping podría ser útil en la disminución del dolor y la normalización de la función muscular.

 

Objetivo: Evaluar la eficacia a corto y a largo plazo del taping en combinación con EC en el tratamiento de LC.

 

Materiales y métodos: Este es un ensayo clínico controlado randomizado. El grupo experimental (GE) utilizó cinta tape y realizó EC y el grupo control (GC) solo realizó EC. Se registraron al inicio y final del tratamiento el dolor conla Escala Visual Análoga (EVA), la flexibilidad con el Modified Finger Tip to Floor Test (MFTF) y la funcionalidad con el Roland Morris Disability Questionnaire (RMDQ).

 

Resultados: Se incluyeron 220 sujetos, completando el tratamiento solo 42 en el GE y 33 en el GC. El delta de dolor entre la primera y la quinta sesión no demostró diferencias entre los grupos independientemente del tiempo (p=0.329). Tampoco hubo diferencias entre los grupos en el RMDQ (p=0.75) así como en el MFTF (p=0.20).

 
Conclusión: El taping en combinación con EC comparado con el tratamiento exclusivo de EC no demostró ser más eficaz en la disminución del dolor, el aumento de la funcionalidad y flexibilidad en los pacientes con lumbalgia crónica
Resolución del caso.
Authors: Ghisi Juan Pablo , Cadena Berecoechea Alejandro
Published: October 2015

Se presenta un caso de traumatismo de baja energía, de dificil el diagnóstico inicial, como el esguince de mediopié. Se presentan imagenes que demuestra realmente lo  ocurrido en dicha zona: pequeñas fracturas alrededor de la articulación de Lisfranc (también llamada lesión sutil de Lisfranc) es una lesion que con un 20-35% de falsos negativos en las radiografías, en donde la sospecha clínica es fundamental. Como examen complementario la RM puede jugar un papel crucial, dado que un diagnóstico precoz de las alteraciones sutiles óseas y de tejidos blandos es esencial para realizar un tratamiento adecuado, evitando así la importante morbilidad que conlleva el diagnóstico tardío.
Distribución del ingreso e imposición a las altas rentas en América Latina
Authors: Amarante Verónica , Jiménez Juan Pablo
Published: October 2015

En la última década los niveles de desigualdad en la distribución del ingreso se han reducido significativamente en América Latina. Esto producto de un crecimiento económico sostenido y la marcada reducción de los niveles de pobreza. No obstante, en términos internacionales la región continúa siendo la más desigual del planeta manteniendo altos niveles de concentración del ingreso. Aunado a esto, las mediciones sobre desigualdad, provenientes de encuestas de los hogares, podrían estar subestimando la alta concentración del ingreso al compararse con mediciones provenientes de registros fiscales, al mismo tiempo que las estructuras tributarias se encuentran sesgadas hacia impuestos indirectos con un más regresivo impacto distributivo.Este artículo propone la incorporación de instrumentos de análisis, basados en los registros tributarios, que permitan mejorar las mediciones sobre la desigualdad, así como cambios en materia impositiva a fin de de aumentar la recaudación y el alcance efectivo de los impuestos sobre los individuos de más altos ingresos.
Editorial
Authors: Ocampo José Antonio
Published: October 2015

La política fiscal tiene impactos sobre el grueso del sistema económico. En primer lugar, es uno de los componentes esenciales de la política macroeconómica y como tal tiene el potencial de afectar la actividad productiva, la balanza de pagos y la inflación. A lo largo del ciclo económico, puede ejercer un efecto procíclico y acentuar o atenuar otros factores internos o externos que actúan sobre estas variables macroeconómicas. Más allá de tales efectos agregados, el gasto estatal contribuye a la provisión de bienes públicos y sociales y, a través de ello y de su forma de financiamiento, tiene efectos significativos sobre el crecimiento económico, el desarrollo humano, la distribución del ingreso y la sostenibilidad ambiental. La forma como se distribuyen las responsabilidades del gasto y las capacidades de generar ingresos entre los Gobiernos nacionales y subnacionales tiene también un impacto importante sobre la estructura regional de las economías.La rica colección de artículos que se recogen en este número de Cuadernos de Economía aborda varios de estos temas y constituye un aporte importante a los debates latinoamericanos y colombianos. Resalta, además, su trascendencia para las discusiones actuales, que corresponden a un coyuntura difícil, donde el impacto negativo de las perturbaciones que provienen de la economía internacional pone en riesgo el crecimiento económico y, sobre todo, los avances sociales que experimentó América Latina durante la última década.Los cuatro primeros artículos analizan la situación latinoamericana desde una perspectiva comparada. En el primero, escrito por Verónica Amarante y Juan Pablo Jiménez, analizan los efectos de la tributación sobre la distribución del ingreso en América Latina, para lo cual incorpora la nueva información sobre altos ingresos proveniente de los registros administrativos en materia tributaria. Los autores corroboran la disminución en la desigualdad en la distribución del ingreso que han experimentado los países de la región en la última década, a pesar de que continúa siendo la más alta del mundo. Esta desigualdad es, además, mucho más acentuada cuando se incluyen los nuevos datos sobre altos ingresos para los pocos países para los cuales están disponibles. Frente a ello, Amarante y Jiménez muestran que el impacto redistributivo de la política fiscal es muy limitado, en especial porque las estructuras tributarias están sesgadas hacia impuestos indirectos.
Cristalización y predicción de la estructura tridimensional de la proteína homóloga del receptor activado para la quinasa c (lack) de leishmania
Authors: Patiño González Edwin , Patiño Márquez Isabel Andrea , Alzate Juan Fernando
Published: October 2015

Los parásitos del género Leishmania son
los causantes de la enfermedad conocida
como Leishmaniasis. Esta enfermedad es
endémica en 98 países. Veinte especies de
Leishmania sp han sido descritas como
patógenos en humanos y varias de ellas
presentan manifestaciones clínicas diferentes.
No se dispone de vacuna, a pesar del
considerable esfuerzo de muchos grupos de
investigación. Las alternativas para descubrir
nuevos medicamentos están basadas en el
diseño de compuestos que interaccionen
con blancos específicos, principalmente,
proteínas encargadas de procesos metabólicos
o celulares del patógeno, e.g. la parasitación
de las células del huésped vertebrado. La
eficiente parasitación del huésped vertebrado
por Leishmania depende de la expresión de
diferentes proteínas, incluyendo la proteína
Lack. Parásitos deficientes de Lack no
sobreviven internalizados en las células de
los vertebrados. Este artículo presenta las
condiciones de renaturalización, purificación
y cristalización de la proteína Lack del
patógeno humano Leishmania (Viannia)
panamensis. Además, los resultados de
modelación estructural de esta proteína
muestran una conformación proteica similar
a un ventilador organizado en 7 aspas, cada
una compuesta de 4 hojas β. La estructura de
la proteína Lack resultó similar a la proteína
asociada a ribosoma RACK1 de Trypanosoma
brucei y Saccharomyces cerevisiae, y a la
de otros eucariotas. Las características
estructurales de la proteína Lack podrían
ser usadas para la exploración de nuevos fármacos
El Impacto del Bono Demográfico en el Sector Educativo Argentino. Periodo 2010-2040. Un Abordaje Interdisciplinario
Authors: Manzano Fernando Ariel
Published: October 2015

Conforme avanza la transición demográfica existe un periodo de tiempo de descenso sostenido de la fecundidad, mientras tanto aún no es muy grande el peso relativo de la población mayor de edad y, por tanto, la principal proporción de la población se concentra en las edades potencialmente activas.Desde la teoría demográficase destaca este periodo por sus ventajas para potenciar el crecimiento económico. Sin embargo, desde la teoría económica, se advierte que la condición necesaria para que tenga éxito el bono demográfico, es elevar los niveles de las tasas de actividad y de empleo. Es decir, garantizar un escenario de crecimiento económico, lo cual implicaría, invertir la causalidad propuesta por la teoría demográfica.Teniendo en cuenta la interrelación entre la dinámica demográfica y económica, el objetivo de este trabajo es cuantificar el impacto de la disminución de la carga de dependencia del sector educativo, en términos económicos.Para poder realizarlo, es necesario realizar una serie de supuestos, que nos permitan hacer depender la evolución del gasto en educación y el crecimiento del PBI, de solamente los cambios en la estructura de edad de la población Argentina durante el periodo 2010-2040, que se desenvuelve conforme se desarrolla la transición demográfica.
Play therapy in the special education of the children with ASD
Authors: Tyulina V.B. , Kats L.I.
Published: October 2015

Access to the method of play therapy allows to actively use it in the framework of comprehensive intervention with children diagnosed with autism spectrum disorders. Problems with play skills that are typical for children with autism require greater flexibility from teachers, whose work should be based on the knowledge of sensory perception and special interest of an individual child. The article describes techniques and methods that are used by play therapists from the parent association Svet in order to promote emotional development, motor skills, social interaction and functional skills through the play activities with children with autism.
New Modular Basic Master's Degree Program in Cultural-Historical and Activity Approach in Education: Development and Approbation
Authors: Rubtsov V.V. , Elkonin B.D.
Published: October 2015

The paper focuses on the specifics of a master's degree program in "Cultural-historical psychology and activity approach in education" offered at the Moscow State University of Psychology and Education. Its key features are the specially developed modules that allow students to explore through an intensive teaching process the most essential issues, modern state and fundamental practices of cultural-historical psychology and activity approach.
The Role of L.S. Vygotsky's Ideas in the Development of Social Cognition Paradigm in Modern Psychology: A Review of Foreign Research and Discussion on Perspectives
Authors: Kholmogorova A.B.
Published: October 2015

The author reflects on the reasons for the increased interest of modern foreign social cognition researchers in L.S. Vygotsky's cultural-historical theory in the light of the existing methodological contradictions and recent empirical data. The paper analyzes the main ideas and concepts of cultural-historical theory that were incorporated in research by Vygotsky's foreign followers, including such prominent experts in the field of social cognition as M. Tomasello and Ch. Fernyhough. It describes the conceptual apparatus and models of development of social cognition in phylo-, anthropo- and ontogenesis proposed by these researchers basing on the ideas of cultural-historical approach. The author especially stresses the importance of the idea of the dialogical nature of human thinking as the foundation for social cognition development in ontogenesis. Also reviewed are the mechanisms underlying the emergence of dialogical thinking from egocentric speech that are described in Ch. Fernyhough's model of social cognition development in ontogenesis. The paper concludes with an analysis of the concepts of cultural-historical theory and its current developments by Russian researchers that are of high heuristic potential for the future development of the paradigm of social cognition.
Concepts of Self-Regulation: A Historical Retrospective
Authors: Bolotova A.K. , Puretsky M.M.
Published: October 2015

Psychology of self-regulation is a relatively new but rapidly developing branch of psychological science. It has integrated many of the ideas that were initially born within the framework of physiology and cybernet¬ics. Interpretations of mechanisms underlying self-regulation are closely related to the general principles of dynamic systems' functioning on the basis of feedback. These principles were defined in the works of the Russian physiologists N.A. Bernstein and P.K. Anokhin and in the cybernetic models of Western scientists. Ideas of L.S. Vygotsky, S.L. Rubinstein, A.N. Leontiev, P. Janet, J. Piaget and others have also had a significant impact on the development of modern concepts of self-regulation. The paper provides a historical insight into the origins of ideas of self-regulation and shows how they have evolved from the concept of self-regulation as adaptation to the concepts of reasonable changes, subjective activity, conscious self-regulation, self-determi¬nation and self-efficacy, and individual styles of self-regulation.
Lenses and Lessons: Using three different research perspectives in early childhood education research
Authors: Irvine S. , Davidson C. , Veresov N.N. , Adams M. , Devi A.
Published: October 2015

In contemporary Western research, collaboration is held in high esteem. This developing practice is chal¬lenging particularly for researchers who follow varying theoretical approaches. However although a challeng¬ing endeavour, when viewing the one data set with different lenses, there are various lessons that can be shared. A key aspect of this paper is involved researchers' different analytical perspectives in one data set to learn more about each other's research insights, rather than become instant expert in other's approaches. The interview data reported in this paper originates from a larger study researching parents' experience of using early child¬hood education and care (ECEC) in Australia. Here we analyse and report on two shared interview excerpts and use three different research lenses for analysis; phenomenographic study, conversational analysis and cul¬tural-historical theory. The finding of this paper demonstrates that applying different lenses provide different interpretations, including strengths, limitations and opportunities. In this paper we argue that collaborative research practices enhance our understanding of varying research approaches and the scope, quality, transla¬tion of research and the researchers' capacity are enhanced.
Solving the Task of Finding the Meaning of Dreams as a Method of Exploring Comprehension of Meanings of Life
Authors: Kubarev V.S.
Published: October 2015

The paper presents outcomes of a quantitative psychotechnological research on the process of one's com¬prehension of his/her own life. It focuses on the reflective mechanisms of realizing meanings of life, thus further developing research on meaning formations of personality within the cultural-activity approach. For these purposes a method of solving the task of finding the meaning of a dream was used in the study, which is in fact an operationalization of the method of productive amplification of consciousness. Rather than examining the already formed contents of meanings of life available for introspective descriptions, this method allows the exploration of the constructive activity of consciousness through which these meanings of life are formed. The main outcome is the reconstruction and empirical model of reflective activity carried out by the individual in the process of comprehending meanings of life and his/her life situation.
Dominant Motivation in Schoolchildren: Age Trends and Conditions of Development
Authors: Kulagina I.Y.
Published: October 2015

The paper addresses the issue of the development of dominant motivation, or motivation of over-situational level, regarded as the general vector that defines basic patterns of behavior of an individual in various situa¬tions and activities. Dominant motivation represents the attitude towards the world (towards other people and work) and oneself and underpins personality orientation on the ontogenetic stage of personality stabilization. The paper describes data of an empirical study carried out on a sample of 403 children and adolescents using an inventory developed by the author. The data provide an insight into the population dynamics of motivation development in school-age children and teenagers. As it was revealed, moral motivation actively develops in early school age, whereas egocentric and hedonistic motivation develops in adolescence. The paper provides characteristics both of motivational profiles that promote socialization in adolescents and of the ones that do not. It concludes that moral motivation dominates in favorable educational and upbringing conditions (in teenagers with normal intellectual development studying at ordinary schools and in gifted children and teenagers with high levels of intellectual development studying at gymnasiums), while hedonistic motivation dominates in children who are brought up in children's homes; homeless adolescents display no differentiation of motives at all.
Análise microbiológica de frutas minimamente processadas servidas em uma Unidade de Alimentação e Nutrição
Authors: Lins A. D. F. , Lisbôa C. G. C. , Moraes M. S. , Sampaio A. C. F. , Quirino D. J. G.
Published: October 2015

Produtos minimamente processados têm sido descrito como produtos manipulados, preparados, embalados e distribuídos, que passam por procedimentos como seleção, limpeza, lavagem, descascamento e corte que não comprometem suas características organolépticas e agreguem valor aos mesmos. Alguns desses procedimentos podem proporcionar lesões que resultam em aceleração da respiração, produção de etileno, senescência, amadurecimento, deterioração e uma contaminação microbiológica. Partindo desse pressuposto, esse trabalho tem como objetivo verificar as condições microbiológicas de mamão, melão, abacaxi e melancia minimamente processados, provenientes de uma Unidade de Alimentação e Nutrição de um município da Região do Cariri do Estado do Ceará. As análises de coliformes totais, termotolerantes e detecção de Salmonella sp, foram realizadas segundo os padrões e metodologias da Americam Public Health Association. Através dos resultados deste trabalho baseados na RDC Nº 12, de 2 de Janeiro de 2001 da Agência Nacional de Vigilância Sanitária, as quatro amostras de frutas apresentaram contagem ≥2,4x103 NMP/g para Coliformes Totais e termotolerantes e ausência de Salmonella sp. Sugere-se assim que sejam revistas as Boas Práticas de Fabricação (BPF), assim como a adoção de um Programa de Análise de Perigos e Pontos Críticos de Controle (APPCC) para garantir um produto de qualidade e seguro para o consumidor.Microbiological analysis minimally processed fruits Food and Nutrition UnitAbstract: Minimally processed products have been described as products handled, prepared, packaged and distributed, passing through procedures such as screening, cleaning, washing, peeling and cutting that do not compromise their organoleptic characteristics and add value to them. Some of these procedures may provide injuries that result in acceleration of respiration ethylene production, senescence, maturation, decay and microbiological contamination. ethylene production, senescence, maturation, decay and microbiological contamination. Based on this assumption, this study aims to determine the microbiological conditions papaya, melon, pineapple and watermelon minimally processed, from a Power Unit Nutrition in a municipality in the State of Ceará Cariri Region. The analysis of total coliforms and thermotolerant and detect Salmonella sp, were performed according to the standards and methodologies of Americam Public Health Association. Through the results of this work based on the RDC No. 12, of 2 January 2001 the National Health Surveillance Agency, 4 samples showed fruit Count ≥2.4x103 MPN /g for total and coliforms thermotolerant and Salmonella sp. To suggest so review the Good Manufacturing Practices (GMP), and the adoption of a Hazard Analysis Program and Critical Control Points (HACCP) to ensure product quality and safe for the consumer.
Arborização em canteiros centrais na cidade de Patos, Paraíba
Authors: Lucena J. N. , Souto P. C. , Camaño J. D. Z. , Souto J. S. , Souto L. S.
Published: October 2015

A arborização de canteiros nas cidades é uma prática que embeleza e permiti reduzir efeitos antropogênicos. O trabalho objetivou quantificar e avaliar a qualidade das árvores localizadas em canteiros centrais da cidade de Patos-PB e o risco que elas representam para a população. Foi realizado o levantamento florístico em 1.391,95 m de canteiros centrais, registrando informações dendrométricas e qualitativas quanto aos aspectos das condições existentes no meio. Foram registrados 166 indivíduos representados em 14 espécies, sendo 71,4% exóticas com destaque para Azadirachta indica e Prosopis juliflora. A maioria das árvores são adultas e medem mais de 10 cm de DAP com altura variando entre 1,6-7,21 m. Em relação à avaliação do risco, não registrou-se indivíduos em conflito com as redes elétricas e sim a presença de galhos ocos nos níveis médio e leve. Na maioria dos indivíduos o sistema radicular apresenta-se subterrâneo, mas, observou-se que 70,1% não apresentam neilóides em superfície, aumentando a suscetibilidade de risco de queda desses indivíduos. Conclui-se que as espécies de maior ocorrência nos canteiros centrais da cidade de Patos são exóticas e que a maioria dos indivíduos sofreram intervenção silvicultural de forma inadequada.Arborization in the medians of the city of Patos, Paraíba EstateAbstract: The arborization in the central urban area of cities is a practice that beautifies urban areas and reduces anthropogenic effects in these areas. The aim of the present study was to measure and assess the quality of trees located in the medians of the city of Patos, PB, through identifying, quantifying and characterizing the vegetation in three different medians and evaluating the risks these trees posed to the population. The analyzed vegetation included 166 individual trees belonging to 14 different species, 71.4% of which were exotic species. The most represented species were Azadirachta indica and Prosopis juliflora. Most of the tress were fully grown and measured over 10 cm DBH with heights ranging from 1.6 to 7.21 m. In relation to risk assessment, there were no specimens that interfered with the electrical networks, but the presence of hollow branches was found in low to medium levels. In most individuals the root systems were located underground, but it was observed that 70.1% of the evaluated trees had surface roots (neilóides), increasing their susceptibility to falling. This study concluded that most of the trees in the medians of Patos city are exotic and most of these trees have suffered inappropriate silvicultural intervention.
Employees’ Service Innovation Behavior and New Service Development in Four- and Five-Star Hotels
Authors: Al-Ababneh Mukhles M.
Published: October 2015

This study aims to explore the impact of Employee Service Innovation Behavior (ESIB) on New Service Development (NSD) among hotels’ employees. A research model was proposed in which one hypothesis was developed. The empirical data were collected from employees who are working in four- and five-star hotels in Jordan. A total of 332 questionnaires were returned and the data were analyzed using a single regression to determine the relationship between ESIB and NSD. The results supported the proposed model that there is a significant relationship between ESIB and NSD, and it also found that service innovation performance is exited in the hotel industry. The theoretical and managerial implications were drawn based on the study findings, and recommendations for future researchers were made, and limitations and conclusions are discussed.
Biometric Technologies in Emergency Management: The Case of Hotels
Authors: AlBattat Ahmad Rasmi
Published: October 2015

The hospitality industry is susceptible to emergencies and disasters and must be managed in order to mitigate potential impacts. This paper explores biometric technology and their potential usage in the hospitality industry. This paper reviews the viable biometric technologies and further with a discussion of their applications in the hospitality industry to enhance security and increase operational efficiency. Tracking employees and hotel guests may bolster emergency management response time by locating individuals, ensuring secure areas, and aiding individuals in evacuation procedures. In this study, various scenarios in which biometrics can be used are explored. The paper concludes with a discussion on the urgent need for biometric technologies to be installed the hospitality industry to reduce errors and eliminate potential terrorist activities.
AUTORREGULAÇÃO: O USO DE DIÁRIOS DE ESTUDO POR ALUNOS DO 5º ANO DO ENSINO FUNDAMENTAL
Authors: Kosour de Oliveira Maria Fernanda , Barboza Tortella Jussara Cristina
Published: October 2015

Este trabalho é um recorte de uma pesquisa de mestrado em que foi analisada
a utilização dos diários de estudo no âmbito dos processos da autorregulação.
Trata-se de uma pesquisa descritiva com análise de dados qualitativos e quantitativos. Participaram do estudo 99 alunos do 5º ano do Ensino Fundamental. A coleta de dados foi realizada diretamente do conteúdo dos diários de estudo e do Inventário de Processos de Autorregulação da Aprendizagem (IPAA). A análise qualitativa do conteúdo dos diários revelou a importância da utilização desse instrumento, enquanto os dados do instrumento IPAA indicaram que a diferença entre o pré e o pós-teste é acentuada e estatisticamente significativa. Os resultados sugerem que o tempo para a consolidação da aprendizagem das estratégias autorreguladoras é fator preponderante.
Palavras-chave: Autorregulação. Diário de estudo. Ensino Fundamental.
SOBRE A CAPA
Authors: Krischnegg Haidi
Published: October 2015

Sobre a Capa
FOLHA DE ROSTO
Authors: Diersmann Admin Débora
Published: October 2015

Folha de Rosto