bluuebunny/crossref_metadata_2025 huggingface dataset:
Insulin supplemented with phenolic fraction concentrates displays anxiolytic and antidepressant-like properties with reductions of oxidative brain damage in chronically stressed diabetic rats
Authors: BIKRI Samir , Talhaoui Abdeljalil , Fath Nada , Hsaini Asmae , Benmhammed Hajar , Ahami Ahmed Omar Touhami , Aboussaleh Youssef
Published: November 2022

Introduction: The current study aimed to investigate if insulin supplemented with phenolic fraction concentrates (PFC) improves chronic hyperglycemia-related behavioral changes by mitigating oxidative stress in diabetic rats exposed to chronic mild stress (CMS). Methods: Experimental type 1 diabetes mellitus (T1DM) was established by a single intraperitoneal injection of streptozotocin (STZ, 65 mg/kg). After diabetes confirmation, rats were treated with insulin supplemented with PFC and exposed to two unpredictable mild stressors per day for 12 weeks. Body weight changes, fasting blood glucose (FBG), and corticosterone levels were evaluated. The behavioral tests were performed to evaluate anhedonia, anxiety, and depressive-like behaviors. Twenty-four hours after behavioral tests, all rats were anesthetized, and the blood was collected for the analysis of lipid, hepatic, and renal parameters. Finally, the brain areas (striatum, hippocampus, and prefrontal cortex), pancreas, and adrenal glands were dissected for the analysis of oxidative stress markers. Results: The results of this study revealed that treatment with insulin supplemented with PFC for 12 weeks significantly enhanced antioxidant defenses (catalase [CAT] and superoxide dismutase [SOD]) and reduced oxidative stress damage (nitric oxide and malondialdehyde [MDA]), especially in brain regions (prefrontal cortex, hippocampus, and striatum) in stressed diabetic rats (P < 0.001). This combination also ameliorated the corticosterone level (P < 0.001) as well as glucose homeostasis (P < 0.001) and lipid parameters (P < 0.001), which are markedly altered in T1D associated with stress. Conclusion: The associated treatment possesses important anxiolytic and antidepressant-like effects in this rat model, which might be mainly mediated by its capacity to protect brain cells against reactive oxygen species (ROS) triggered by T1DM and/or chronic stress.
Analisa Pengaruh Pemasangan Fuse Saver di Penyulang Karang Joang 13 PT PLN (Persero) UP3 Balikpapan
Authors: Kristian Tridiyah Ayu
Published: November 2022

Sistem distribusi mempunyai perangan sebagai penyalur tenaga listrik yang berhubungan secara langsung dengan konsumen. Dalam proses penyaluran tenaga listrik tidak menutup kemungkinan terjadinya gangguan yang dapat mempengaruhi keandalan suatu sistem distribusi. PT PLN (Persero) adalah perusahaan yang bertugas untuk mengelola system ketenagalistrikan di Indonesia yang diwajibkan untuk selalu meningkatkan mutu dan kualitas pelayanan serta keandalannya dalam pendistribusian energi listrik. Sesuai dengan tujuan PT PLN (Persero) yaitu tercapainya kepuasan konsumen. Untuk meningkatkan keandalan penyulang Karang Joang 13 dan meminimalisir gangguan maka dipasang alat proteksi yang disebut fuse saver.

Pada penelitian menggunakan data rekap gangguan penyulang Karang Joang 13 sebelum dan sesudah pemasangan fuse saver. Data dianalisis dengan membandingkan nilai SAIDI, sSAIFI, CAIDI, CAIFI, dan ENS, serta Rupiah pendapatan yang hilang. Selain itu diperlukan pula data single line diagram dan data beban gardu di penyulang tersebut. Data-data ini diperoleh dari database PT PLN (Persero) ULP Balikpapan Utara. Sedangkan untuk waktu penelitian dimulai di Bulan Maret Tahun 2022.

Hasil penelitian menunjukkan setelah dilakukan pemasangan fuse saver, gangguan penyulang turun 47% menjadi 18 kali, SAIDI turun 97% menjadi 0,06 jam/tahun, SAIFI turun 56% menjadi 1 kali/tahun. Begitu pula dengan CAIDI dan CAIFI masing-masing turun sebesar 95% dan 16% menjadi 0,12 jam/tahun dan 7,98 kali/tahun. Di sisi lain, ENS juga mengalami penurunan sebesar 96% menjadi 1.356kWh dan rupiah pendapatan yang hilang turun 96% menjadi Rp 1.930.736,-. Jika dibandingkan dengan Standar SPLN 68-2:1986 dan IEEE std 1366-2003 juga masih berada di bawah standar.Oleh karena itu dapat dikatakan bahwa pemasangan fuse saver dapat mempengaruhi keandalan pada penyulang Karang Joang 13.
Changes in Physical and Mental Health Indicators of Law Enforcement Officers in the Process of their Professional Activities
Authors: Okhrimenko Ivan М. , Volynets Nataliya V. , Penkova Natalia E. , Dekhtiarenko Iryna S. , Hresa Nataliia V. , Onishchuk Larysa M. , Okhrimenko Svitlana S.
Published: November 2022

Aim: To study the level and dynamics of physical and mental health indicators of officers-in-charge of police organizations in the process of their professional activities.
Materials and Methods: The research which was conducted in the period from 2019 to 2021 and involved 155 law enforcement officers (men) of different age groups, who held superior positions in various police departments. The physical health of law enforcement officers was assessed according to the method of H.L. Apanasenko, mental – using a mix of psychodiagnostic methods.
Results: It was found that the level of physical health of the officers-in-charge of police organisations is significantly deteriorating with increase in their age and professional experience. The level of health of the majority of superior law enforcement officers is below average and low. The negative dynamics of health indicators of law enforcement officers was revealed during the research period. It was found that the law enforcement officers with a high level of physical fitness have significantly better indicators of mental health than the ones with a low level of physical fitness.
Conclusions: One of the main reasons for the low level of physical and mental health of superior police officers is the lack of effectiveness of physical training sessions and, as a result, their low level of physical fitness. All this requires the improvement of physical training with this category of law enforcement officers in order to strengthen their physical and mental health and improve the indicators of their professional activities.
Integrated Assessment of Macrophage Lipids Homeostasis Omics Data: Identification of Potential Genes and Pathways in Atherosclerosis
Authors: Siew Wei Sheng , Tang Yin Quan , Yap Wei Hsum
Published: November 2022

Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid-rich plaques within the arterial wall. Increasing evidences have shown that cellular senescence may contribute to the progression of atherosclerosis, but the mechanism remains unclear. Hence, the present study aimed to identify potential therapeutic biomarkers for atherosclerosis by analyzing the gene expression profiles of macrophages incubated with total lipoproteins. The microarray dataset no. GSE84791 obtained from Gene Expression Omnibus (GEO) database was used for this study. In the comparison of two groups: (i) THP-1 macrophage models incubated with non-LPL hydrolysed products and (ii) LPL hydrolysed products, a total of 283 differentially expressed genes (DEGs) were identified. The Gene Ontology (GO) analysis indicated that the upregulated DEGs gene set were mainly enriched in cellular response to inflammation, stress, substance uptake and intracellular transport. Besides, upregulated DEGs were significantly enriched in PPAR signalling pathway by the Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Notably, GO analysis revealed that the downregulated DEGs were mainly enriched in cellular proliferation, while the KEGG analysis showed that the gene set was significantly enriched in cell cycle process. The top 10 hub genes including KIF2C, NCAPG, BUB1, TOP2A, CENPF, TTK, CCNA2, PLK4, CDC6, and KIF11, was identified from the Protein-Protein Interaction (PPI) network, which constructed using STRING and further analysed using the Network Analyzer, MCODE and cytoHubba. The present study indicated that the downregulation of these genes which involved in the process of cell cycle may have an implication on atherosclerosis development.
Особливості створення та застосування наземних роботизованих комплексів у провідних країнах світу та Україні
Authors: Залипка В. Д.
Published: November 2022

Встановлено, що під час ведення бойових дій, а зокрема і в ході російсько-української війни, наземні роботизовані комплекси (НРК) відіграють важливу роль у збереженні життя та здоров'я військовослужбовців. Тому для якісного виконання завдань згідно зі своїм призначенням, а отже, і переваги над противником, їх необхідно мати в достатній кількості і вони повинні володіти покращеними експлуатаційними властивостями. З'ясовано, що провідні країни світу такі, як: Сполучені Штати Америки (США), Велика Британія, країни Європейського Союзу, Японія, Південна Корея, Китай – однозначно визначились, що війни майбутнього, – це війни роботів (роботизованих комплексів). Основним чинником розвитку сучасних будь-яких роботизованих систем провідних країн світу є активне впровадження інноваційних технологій, зокрема штучного інтелекту. США сьогодні в авангарді щодо розробок та впровадження НРК, про це, зокрема, свідчать їх керівні документи, а саме: Стратегія роботизованих і автономних систем армії США (RAS) до 2035 р., Операційна концепція армії США до 2040 р. та Інтегрована дорожня карта безпілотних систем на 2017-2042 роки. Визначено, що з огляду на характер покладених на НРК завдання (бойового, тилового, технічного та медичного забезпечення), найбільш доцільно класифікувати їх за функціональним призначенням та поділяти на три групи (бойові, спеціальні, багатоцільові). Проаналізовано Стратегію армійських робототехнічних і автономних систем, Операційну концепцію армії США до 2040 р. та Дорожню карту розробки та впровадження роботизованих, зокрема наземних, комплексів США та з'ясовано: як їх військово-політичне керівництво інтегруватиме нові технології в майбутні проєкти, щоб забезпечити собі перевагу над щораз більше підготовленим у технологічному плані противником, також і те, що фахівці-розробники та представники збройних сил США зіткнулися із низкою проблем, які в ході реалізації стратегії та дорожньої карти намагаються вирішити. Узагальнено структуру НРК та враховуючи світові тенденції щодо розробок відповідних систем, окреслено кроки щодо роботизації підрозділів ЗС України з проблемними питаннями та пріоритетними напрями їх вирішення. Визначено з положень Концепції розвитку та застосування НРК (платформ) у підрозділах Сухопутних Військ (СВ) ЗС України, що НРК під час застосування у складі підрозділів СВ ЗС доповнюють (замінюють) традиційні види озброєння і військової техніки практично у всіх формах і способах застосування підрозділів.
Sistem Pendukung Keputusan Penerima Program Keluarga Harapan (PKH) dengan Metode Simple Additive Weighting (SAW)
Authors: Riyanti Lisa , Ali Gunawan , Amril
Published: November 2022

The Family Hope Program (PKH) is a program for providing conditional assistance to Beneficiary Families (KPM) who are designated as PKH beneficiary families. This PKH program provides cash assistance to very poor households (RSTM) that meet the requirements and are related to efforts to improve the quality of life in the fields of education and health. However, in the management of PKH data, several problems were found, such as in the distribution aspect. In the distribution aspect, it is often found that the distribution of PKH is not right on target or the distribution of PKH to families who do not deserve this PKH program. Various efforts have been made to overcome these problems, one of which is by making a decision support system using the Simple Additive Weighting (SAW) method. The decision support system with the SAW method can provide recommendations or support to determine the right PKH recipients. The SAW method is a weighted addition method, which is looking for a weighted sum of ratings for each alternative on all attributes/criteria. The result of the total score obtained for an alternative is by adding up all the multiplication results between the ratings compared across attributes and the weight of each attribute. The Decision Support System for determining PKH recipients using the SAW method provides the right results. The alternative is the highest order to have a good score on the criteria that have the highest importance and is very precise with real data so that the distribution of PKH is right on target.
The Use of Social Media for Students' Academic Life: Experience from Buhare Community Development Training Institute, Musoma, Tanzania
Authors: Saidi A. Mbegani  , Henry L. Mambo  , Christian Mubofu
Published: November 2022

The study assessed the usage of social media networks in seeking information by college students: with reference to Buhare Community Development Training Institute (CDTI), Musoma-Mara region, Tanzania. Data were collected from two hundred seventy-three (273) study participants using questionnaires. The sample of the study was representative. The results from the analysis showed that Buhare CDTI students were familiar with social media while performance and efficiency was the highly cited factor influencing the choice of social media. Study findings further showed that social media sites were a reliable source of information for academic purposes and the majority of the participants noted that the reason for use of social media was academic and information-sharing purposes. Additionally, the majority of the participants revealed that there was a strong relationship between the extent of their use of social media and their academic performance. The study further established that the high cost of Internet bandwidth, identifying the author of materials retrieved from social media sites due to information overload, and failure to discover reliable information to be used on academic references due to the flood of information from social media were the critical challenges faced by students. Conclusively, it was clear from the current study that social media platforms are reliable sources of information to be used by college students in their daily academic life. The study suggests that academic institutions should promote and motivate students to use social media in their daily academic activities. Also, tutors and all academic stakeholders have to train students so that they may have the skills and knowledge to use IT devices.
Efecto de una intervención nutricional en el consumo de alimentos en escolares de educación básica de Reynosa, Tamaulipas, México
Authors: Ríos-Reyna Candelaria , Castillo-Ruíz Octelina , Díaz-Ramírez Glenda , Almanza-Cruz Ocairi , Vázquez-Nava Francisco , Alemán-Castillo SanJuana Elizabeth
Published: November 2022

In recent years, the consumption of ultraprocessed foods in schoolchildren has increased and this has been linked to an increase in the prevalence of childhood obesity. Objective: To calculate the size of the effect of a nutritional intervention on food consumption in basic education schoolchildren in Reynosa, Tamaulipas, Mexico. Materials and methods: Longitudinal study, with a sample of 309 schoolchildren from 12 public elementary schools; two groups were formed: intervention (IG) and control (CG) with a follow-up of one year. Measurements of weight, height and waist circumference were made. To evaluate the foods included in school lunch, a food registry was used before and after the intervention and they were characterized as recommended and not recommended. The effect size (ES) was calculated using the Hedges’g statistic. Results: At the end of the study in both groups, water consumption increased, however the ES was big in the IG (ES=0.84); while in the CG it was moderate (ES=0.50). In the IG, a small reduction in the consumption of processed meats was observed (p=0.004; ES=0.28), sweet cereals (p=0.001; ES=0.36) and sweetened nondairy beverages decreased (p=0.001; ES=0.49); while the CG showed a small increase in the consumption of fast food and Mexican appetizers (p=0.001; ES=0.46). Conclusions: In the IG showed a TE small decrease in consumption of processed meats, sweet cereals, and sweetened non-dairy beverages. It is necessary to design strategies that promote the consumption of recommended foods.
How robust are wearable eye trackers to slow and fast head and body movements?
Authors: Hooge Ignace T. C. , Niehorster Diederick C. , Hessels Roy S. , Benjamins Jeroen S. , Nyström Marcus
Published: November 2022

How well can modern wearable eye trackers cope with head and body movement? To investigate this question, we asked four participants to stand still, walk, skip, and jump while fixating a static physical target in space. We did this for six different eye trackers. All the eye trackers were capable of recording gaze during the most dynamic episodes (skipping and jumping). The accuracy became worse as movement got wilder. During skipping and jumping, the biggest error was 5.8∘. However, most errors were smaller than 3∘. We discuss the implications of decreased accuracy in the context of different research scenarios.
Studies of probe tip materials by atomic force microscopy: a review
Authors: Xu Ke , Liu Yuzhe
Published: November 2022

As a tool that can test insulators' surface morphology and properties, the performance index of atomic force microscope (AFM) probes is the most critical factor in determining the resolution of microscopy, and the performance of probes varies in various modes and application requirements. This paper reviews the latest research results in metal, carbon nanotube, and colloidal probes and reviews their related methods and techniques, analyses the advantages and disadvantages of the improved probes compared with ordinary probes by comparing the differences in spatial resolution, sensitivity, imaging, and other performance aspects, and finally provides an outlook on the future development of AFM probes. This paper promotes the development of AFM probes in the direction of new probes and further promotes the broader and deeper application of scanning probe microscope (SPM).
Model Proses Inovasi Kurikulum Merdeka Implikasinya Bagi Siswa Dan Guru Abad 21
Authors: Kurniati Pat , Kelmaskouw Andjela Lenora , Deing Ahmad , Bonin Bonin , Haryanto Bambang Agus
Published: November 2022

Penelitian ini bertujuan untuk ngeuak serta menggali tentang; 1) bagaimana Model Proses Inovasi Kurikulum Merdeka?; 2) bagaimana implikasi kurikulum merdeka bagi siswa dan guru di indonesia pada abad 21?. Berdasarkan Jenis dan Analisisnya Penelitian tentang merdeka belajar ini adalah termasuk penelitian Kualitatif. Dimana sumber penelitian diperoleh dari berbagai sumber kepustakaan seperti buku, jurnal, internet, serta sumber lainnya yang relevan. Hasil penelitian menunjukkan bahwa; 1) Model Proses Inovasi Kurikulum Merdeka dilakukan melalui pengurangan Kompetensi Dasar untuk setiap mata pelajaran sehingga guru dan siswa dapat lebih fokus pada kompetensi esensial untuk kelanjutan pembelajaran di tingkat selanjutnya, dimana Esensi merdeka belajar adalah kebebasan guru dan siswa dalam proses pembelajaran; 2) Sedangkan implikasi kurikulum merdeka bagi siswa dan guru di Indonesia adalah terkait karakteristik yang digunakan dalam kurikulum ini yakni siswa dan guru secara bersama-sama melaksanakan Pembelajaran berbasis proyek untuk mengembangkan soft skill dan karakter sesuai profil pelajar Pancasila, dimana Fokus kepada materi esensial sehingga ada waktu untuk pembelajaran yang mendalam bagi kompetensi dasar antara lain: literasi dan numerasi. Selain itu Fleksibilitas guru untuk melakukan pembelajaran yang terdiferensiasi sesuai kemampuan peserta didik.
Urgensi Pendidikan Pancasila Sejak Dini Bagi Generasi Z
Authors: Sutisna Mohamad , Sucherman Us Us , Suandi Dedi , Sukatmi Sukatmi , Kumalasari Siti
Published: November 2022

Penelitian ini bertujuan untuk mengetahui serta menganalisis tentang bagaimana Urgensi Pendidikan Pancasila Sejak Dini Bagi Generasi Z?. Metode penelitian ini adalah penelitian kepustakaan, dimana sumber data diperoleh dari berbagai buku-buku, jurnal dan internet, serta sumber lainnya yang relevan. Hasil Penelitian Menunjukkan bahwa Urgensi Pendidikan Pancasila Sejak Dini Bagi Generasi Z sangat penting dilakukan, hal ini dikarenakan dengan adanya pendidikan pancasila diharapkan agar generasi muda tidak tercabut dari akar budayanya sendiri dan agar mereka memiliki pedoman atau kaidah penuntun dalam berpikir serta bertindak dalam kehidupan sehari-hari dengan berlandaskan makna serta nilai-nilai Pancasila. Selain itu Penerapan Pendidikan Pancasila Melalui Media Sosial Bagi Generasi Z sangat efektif dan efisien, hal ini dikarenakan adanya kedekatan Generasi Z (Pemuda Indonesia) dengan Media Sosial yang kini sedang trend.
Peningkatan Kemampuan dan Keterampilan Digital Marketing pada Kelompok UMKM Pengrajin Komunitas Sumsel Crafters Palembang
Authors: Martini Rita , Febrianty Febrianty , Sepriansyah Ahmad Ari Gunawan
Published: November 2022

Mitra Program PIM adalah Komunitas UKM Perajin Sumsel yang beralamat di Jl. Yayasan 2 Lrg. Tanjung Kates Kec. Ilir Timur II Palembang. Mitra terdiri dari 115 perempuan pengrajin yang tersebar di Sumatera Selatan, dengan rata-rata lulusan SLTA dan ada pula yang memiliki ijazah/sarjana, dengan rentang usia 20-40 tahun. Mitra merupakan komunitas UKM yang produktif tetapi juga merasakan dampak dari Pandemi Covid-19 yang mengurangi omset bisnis dan hampir membuat mereka beralih ke bisnis lain. Mitra memproduksi aneka kerajinan berupa boneka memakai baju adat Aesan Gede, topeng, dan tas yang terbuat dari kain songket atau tenun, aneka kerajinan untuk kebutuhan rumah tangga, hampers, dekorasi mahar/hantaran, fashion, dan aneka hiasan dinding (macrame, rotan,dll) serta berbagai aksesoris wanita (dari kain flanel, kawat, rajutan). Berdasarkan prioritas masalah yang harus ditangani tim pengabdi akan mengimplementasikan teknologi digital e-catalog dan marketplace/aplikasi kepada mitra dalam rangka pendampingan pengelolaan keuangan dan pelatihan biaya produksi/ HPP serta penggunaan aplikasi keuangan dan menonjolkan keunikan produk dan merek produk, meningkatkan omzet penjualan kerajinan tangan para pelaku UMKM Perajin Sumsel melalui implementasi marketplace IBS (berbasis android) dan ecatalog digital Sumsel Crafter (e-catalog SC) yang mendukung Era Revolusi Industri 4.0. Analisis yakni tahap I situasi dan kondisi Mitra, tahap II penyiapan dan diseminasi teknologi, Tahap III pelatihan dan pendampingan, Tahap IV Program Evaluasi dan Keberlanjutan. Metode yang diterapkan dalam pelaksanaan dan pendampingan pelaksanaan MBKM secara luring dan daring. Manfaat yang dirasakan oleh mitra berupa peningkatan daya saing sebesar 83 persen. Peningkatan Penerapan IPTEK di masyarakat sebesar 81% dan perbaikan tata nilai masyarakat sebesar 84%.
Rancang Bangun System Informasi Management Inventory Berbasis Web Menggunakan Prototype (Studi Kasus: Toko Abadimas)
Authors: Ilham Muhammad , Kartini Kartini
Published: November 2022

Toko Abadimas sebuah bisnis yang bergerak di bidang penjualan perlekangkapan konveksi ataujahit-menjahit dimana dalam mengolah data persediaan barang masih menggunakan cara manualdengan membuat catatan, sehingga sering terjadi kekosongan barang. Tujuan penelitian kali ini ialahuntuk mengetahui sistem manajemen pengolahan inventory di Toko Abadimas, melakukanperancangan sistem informasi manajemen inventori berbasis web. Pada rancang bangun aplikasi inidigunakan metode Prototype dimana system dirancang berdasarkan kebutuhan di Toko Abadimas.Tahap pertama yakni menganalisis dari proses bisnis yang berjalan menggunakan metode PIESCESdan observasi guna mengetahui Performance, information, Economy, Control, Economy danservice. Kemudian dilakukan perancangan sistem dengan bantuan diagram-diagram UML. Tahapselanjutnya implementasi terhadap sistem tersebut menggunakan Framework Laravel. lanjut ketahap pengujian sistem menggunakan metode pengujian blax box. Hasil penelitian ini yaitu aplikasimanajemen inventory berbasis website untuk pengelolaan stok barang.
The Performance of Risk Scoring Systems Used for Severe COVID-19 Cases in The Emergency Department
Authors: ERTEKİN Birsen , YORTANLI Mehmet , ÖZELBAYKAL Ozan , DOĞRU Ali , GİRİŞGİN Abdullah Sadık , ACAR Tarık
Published: November 2022

Objective: The aim of this study is to evaluate the performance of CURB-65, Quick Sequential Organ Failure Assessment (qSOFA), and National Early Warning Score 2 (NEWS 2) scores in predicting mortality in COVID-19 patients in emergency department.

Method: A total of 502 patients diagnosed with severe COVID-19 in the emergency department of a pandemic hospital were analyzed retrospectively. Demographic, clinical and laboratory data of the patients were obtained from the hospital registry system. The CURB-65, qSOFA, and NEWS2 scores of each patient were calculated separately. These patients were divided into two groups as those who survived and those who died. All parameters and calculated risk scores were statistically compared between these two groups.

Results: While 281 out of 502 patients survived, 221 died. When the CURB-65, NEWS2, qSOFA scores were compared between the two patient groups, a significant difference was found (p
The Challenge of Ruling Out Inflation via the Primordial Graviton Background
Authors: Vagnozzi Sunny , Loeb Abraham
Published: November 2022

Recent debates around the testability of the inflationary paradigm raise the question of how to model-independently discriminate it from competing scenarios. We argue that a detection of the cosmic graviton background (CGB), the relic radiation from gravitons decoupling around Planck time, would rule out the inflationary paradigm, as realistic inflationary models would dilute the CGB to an unobservable level. The CGB contribution to the effective number of relativistic species, ΔN
eff,g
≈ 0.054, is well within the reach of next-generation cosmological probes. We argue that detecting the high-frequency stochastic gravitational wave background associated to the CGB will be challenging but potentially feasible. We briefly discuss expectations within alternatives to inflation, focusing on bouncing cosmologies and emergent scenarios.
Evaluation of Three Bridging Tricorticocancellous Bone Grafts in the Treatment of Old Non-uniting Fractured Humerus
Authors: Alkhuzai Ahmed
Published: November 2022

Background: Nonunion of humeral shaft fracture after conservative treatments or frequent failed surgical treatment of bone healing exemplify the difficulties in managing a bone defect or severely damaged individuals. Aim of the study: The present study was undertaken to evaluate three bridging tricoticocancellous bone grafts in the treatment of old non-uniting fractured humerus. Materials and Methods: From June 2014 to December 2019, three bridging tricoticocancellous bone grafts were used to treat non-union humeral shaft fractures using dynamic compression plates at Sulaimani Teaching Hospital in Iraq. Results: Sixteen patients, 11 males, and 5 females, varying in age from 28 to 64 years old (mean age 41) were recruited for the study. Six patients had previously undergone conservative treatment, and ten patients had previously undergone surgical treatment, such as open reduction and internal fixation with plates and screws or various intramedullary nails. Four out of ten patients had previously received bone transplants in conjunction with internal fixation. The nonunion lasted between 2 and 4 years (a mean of 3 years). In patients who were treated by recanalization of the medullary canal healing rate of a non-uniting fractured shaft, humerus reached 100% in all 16 patients, indicating improvements in both bone healing and functional index outcomes. The satisfaction rate score was in 15 patients (93.75%). Also, the function score was excellent in 15 patients (93.75%), while the movement score was in 14 patients (87.5%). The union rate, angular deformity, and limb shortening were used to evaluate bone results. Conclusion: When using the technique of medullary recanalization opening the bone canal, and fixation by dynamic compression plate for old non-uniting fractured shaft humerus patients, the findings confirm that three bridging tricoticocancellous bone grafts are superior in healing and union, improved arm function, and a high satisfaction rate as achieved.
Dietary Factors and Changes in Blood Pressure in Adult Kazakhs: A 3-year Follow-Up Study
Authors: Tuleuova Raushan , Zhamaliyeva Lazzat , Grjibovski Andrej
Published: November 2022

BACKGROUND: As in the world and Kazakhstan’s clinical protocols for the treatment of AH, it is proposed to limit the intake of salt to <5 g/day and alcohol as a dietary therapy, as well as an increase in the consumption of vegetables, fresh fruits, fish, nuts, and sources of unsaturated fatty acids, to reduce the consumption of meat as a source of saturated fatty acids (SFA); consumption of low-fat dairy products. However, it remains unclear how the traditional diet of Kazakhs, which is dominated by sources of carbohydrates and fats with its subspecies, affects the development of AD in the Kazakh population. Local epidemiological and clinical data are required for the successful work of doctors with the population in the prevention of diseases of the blood circulatory system and the creation of clinical recommendations.

AIM: The aim of this investigation was to evaluate an influence of fats, its subspecies, and carbohydrates on BP change after 3-year observation of adult Kazakhs.

MATERIALS AND METHODS: There is described data of 96 individuals of the Kazakh population recruited by the cluster method, living in Aktobe, the Republic of Kazakhstan. Clusters were 14 polyclinics in Aktobe, of which three outpatient municipal polyclinics were randomly selected, each of which had one attached site. From the list of attached adults, also randomly selected 96 people without a history of cardiovascular events.

RESULTS: Average age of participants of the study was 61.9 ± 10.8. None of the participants had a special diets or food restrictions for health reasons or personal beliefs. Body mass index was 27.1 ± 8.4. The over half of the study participants practice on smoking. The average level of SBP in the study’s participants was initially 124.6 mmHg, after 3 years, it increased by an average of 8.6 mmHg and became 133.2, the average level of DBP was 82.2 mmHg, which became higher by 6.2 mmHg and became 88.4 mmHg. According to the regression analysis, higher consumption of carbohydrates, MUFAs, SFAs, and total fats increased SBP by 9.3, 12.3, 46.1, and 5.3 mmHg, respectively. However, with the use of PUFAs, an inverse relationship was found, an increase in PUFA sources in the diet by 100 g reduces SBP by 43.3 mmHg. An effect of all nutrients was not significantly reduced at 3 years on SBP when adjusted for age, sex, and waist circumference.

CONCLUSION: In accordance with the performed analysis in this cohort of subjects, that a significant percentage of these people are overweight or obese, the diet of the Kazakh population does not differ from the eating habits of residents of other countries. The examined individuals received an excess amount of energy from carbohydrates, fat, and SFA, an irrational diet was significantly correlated with an increase in blood pressure.
Role of Stress-induced Diastolic Dysfunction in Weaning Failure from Mechanical Ventilation
Authors: Rafea Mostafa , Mashhour Karim , Fawzy Mohamed , Zaghla Hanan , El-Gengihi Sherin
Published: November 2022

Introduction: Critically ill patients may suffer varying degrees of myocardial dysfunction which can cause weaning failure. Stress echocardiography may be helpful in detecting silent diastolic dysfunction (DD) while weaning off mechanical ventilation [1].
Objectives: assess the existence of temporary DD during respiratory weaning using stress echocardiography.

 

Methods: Our study was conducted on 60 ventilated patients admitted to the department of critical care, Cairo University. Stress echocardiography was done using dobutamine to assess DD and pulmonary capillary wedge pressure using E/e′ ratio.

 

Results: a total of 34 patients (56.66%) was successfully weaned of mechanical ventilation 26 patients (43.3%) had failed weaning of mechanical ventilation. Patients with successful weaning had no statistically significant difference regarding the E/e\ ratio before and after stress testing (P value: <0.001). While patients with failed weaning had statistically significant difference regarding the E/e\ with a mean E/e\ ratio of 11.11 ± 4.44 after stress testing vs. 6.5 ±1.39 before stress testing, (P value was <0.001).
Conclusion: Diastolic dysfunction is a predisposing factor for weaning failure. In addition, stress echocardiography can detect silent diastolic dysfunction during respiratory weaning.
Exceptional larval morphology of nine species of the Anastrepha mucronota species group (Diptera, Tephritidae)
Authors: Rodriguez Erick J. , Steck Gary J. , Moore Matthew R. , Norrbom Allen L. , Diaz Jessica , Somma Louis A. , Ruiz-Arce Raul , Sutton Bruce D. , Nolazco Norma , Muller Alies , Branham Marc A.
Published: November 2022

Anastrepha is the most diverse and economically important genus of Tephritidae in the American tropics and subtropics. The striking morphology of the third instars of Anastrepha caballeroi Norrbom, Anastrepha crebra Stone, Anastrepha haplacantha Norrbom & Korytkowski, Anastrepha korytkowskii Norrbom, Anastrepha nolazcoae Norrbom & Korytkowski, and three newly discovered and as yet formally unnamed species (Anastrepha sp. Peru-82, Anastrepha sp. nr. protuberans, and Anastrepha sp. Sur-16), and the more typical morphology of Anastrepha aphelocentema Stone, are described using light and scanning electron microscopy. To contribute to a better understanding of the interspecific and intraspecific variation among species in the mucronota species group and facilitate phylogenetic studies, we integrate molecular and morphological techniques to confirm the identity and describe third instars. Larva-adult associations and the identification of described larvae were confirmed using DNA barcodes. We provide diagnostic characters to distinguish larvae among these nine species of the mucronota group and separate them from those of the 29 other Anastrepha species previously described. We introduce the vertical comb-like processes on the oral margin as a novel character, and the unusual character states, including position and shape of the preoral lobe, and dentate or fringed posterior margins of the oral ridges and accessory plates. Our comparative morphology concurs with most previously inferred phylogenetic relationships within the mucronota group.
Économies du Sud : toujours sous conditions néolibérales ?
Authors: The Reality of Aid Network  , Bauvir Anne-Sophie
Published: November 2022

La Banque mondiale utilise son pouvoir de créancier pour imposer des conditionnalités aux pays du Sud. Celles-ci ont changé de nom, mais continuent d’être mises en œuvre dans le cadre des « financements à l’appui du développement ». Les exemples des Philippines et de l’Indonésie démontrent le caractère nocif de cette politique qui tend à éroder les souverainetés nationales, démanteler le droit du travail et affaiblir les normes environnementales.
Congolese edible caterpillars, valuable sources of bioactive compounds with human health benefits
Authors: Kapepula P. Mutwale , Wamba H. Luzayana , Lukusa D. Mukundi , Franck T. , Bahati P. Lokole , Fundu T. Mbemba , Dibungi P. Kalenda , Kabamba N. Ngombe , Serteyn D. , Frédérich M. , Mouithys-Mickalad A.
Published: November 2022

Insects are part of the regular diet of more than two billion people around the world and are not only delicacies. Insects provide great opportunities to replace meals but can have important additional benefits as well. In the Democratic Republic of the Congo (DRC), caterpillars are the most consumed insects, and they are consumed by more than 70% of the population throughout the year. The aim of this research was to report the microscopic features, mineral micronutrients, chromatographic fingerprints, antioxidant activities and peroxidase inhibition of edible Congolese caterpillars of the genusCinabra, Imbrasia andGonimbrasia from DRC. Microscopic analysis showed the presence of characteristic features, specific to each host plant of caterpillars, such as palisade cells, stomata, trichomes, sclereids, fibres, vessels, pollen and starch grains. Phytochemical screening by chromatographic techniques revealed the presence of phenolic acids, flavonoids and terpenes as major secondary metabolites. Elemental analysis on dry matter showed that studied caterpillars are insects containing significant amounts of micronutrients such as copper, magnesium, manganese, selenium and zinc.Gonimbrasia belina had the highest selenium, magnesium and zinc content (0.12 g/100 g, 0.17 g/100 g and 0.011 g/100 g, respectively) thanCirina forda, Cinabra hyperbius, Imbrasia truncata andImbrasia sp., C. forda andImbrasia sp. had the highest copper content (0.003 g/100 g).C. forda had the highest manganese content (0.006 g/100 g). All aqueous extracts displayed high radical-scavenging activities with IC50 values ranging from 10 to 80 μg/ml. Extracts showed the best cellular antioxidant activities on reactive oxygen species-induced chemiluminescence using L012 on human leucocytes 60 monocytes related to their IC50 values less than 0.5 μg/ml. In specific immuno-extraction followed by enzymatic detection of myeloperoxidase assay, all extracts of caterpillars exhibited a dose-dependent inhibitory effect on myeloperoxidase activity in the range concentrations of 1 to 20 μg/ml excepted extracts ofImbrasia epimethea,Imbrasia sp. andI. truncata. Our results showed that insects are not only valuable source of lipids, proteins and micronutrients such as selenium but also are sources of phytochemicals with therapeutic benefits.
Vegetation structure of bio-belts as agro-environmentally-climatic measures to support biodiversity on arable land: A case study
Authors: Hanusová Helena , Juřenová Karolína , Hurajová Erika , Vaverková Magdalena Daria , Winkler Jan
Published: November 2022

Loss of biological diversity is one of the greatest challenges that our civilization must face nowadays. Reaction to the diminishing biodiversity of agricultural landscapes is various measures promoting free-living organisms. The study deals with the vegetation composition and structure of agro-environmental-climatic measures applied on arable land in operating conditions (intensively farmed regions of the Czech Republic). Additional study focus was applied to a popular measure of the feeding bio-belts. Bio-belts are not only hiding places for free-living animals but can provide them a rich food offer in the period from the harvest of main crops until winter. Thanks to the bio-belts, the landscape gains in biodiversity, and sloping sites can be protected from soil erosion. The vegetation of land parts used as bio-belts was assessed using phytocoenological relevés. Dominant plant species sown in the bio-belts were Avena sativa, Panicum miliaceum, Brassica oleracea var. acephala, Fagopyrum esculentum, Phacelia tanacetifolia, and Pisum arvense. Apart from the sown plants, there were also weeds occurring in the bio-belts, of which the most abundant were Chenopodium album, Amaranthus retroflexus, Setaria verticillata, Cirsium arvense, Equisetum arvense, etc. Risks connected with the realization of feeding bio-belts in respect of weeds occurring on arable land are negligible. Weeds from bio-belts have only a limited potential to spread to adjacent arable land. A potential spreading of weeds from the bio-belts to adjacent arable land was not demonstrated. On the contrary, thanks to its composition, the vegetation of bio-belts has the potential to extend the food offer for animals. Thus, bio-belts are useful for supporting biodiversity in regions intensively used for agriculture.
Arte y política en la colonia polaca en España durante la Primera Guerra Mundial
Authors: García García Isabel
Published: November 2022

Durante la Primera Guerra Mundial, y gracias a la neutralidad española, se constituyó una interesante colonia de polacos en Madrid. La creación del Comité Nacional Polaco en la península, liderado por el conde Dzieduszycki, un personaje cuya integración social y política en la capital fue clave, posibilitó entre otras actuaciones la Exposición de los Pintores Polacos ―Wladyslaw Jahl, Józef Pankiewicz, Wanda Pankiewicz, Waclaw Zawadowski y Marjan Paszkiewicz― en el patio del Ministerio de Estado. El arte de vanguardia polaco no estuvo exento de una crítica negativa y, aun así, tras la muestra algunos de sus miembros continuaron su trayectoria en el movimiento ultraísta. En definitiva, un interesante capítulo que formó parte del desarrollo de la vanguardia artística española de la primera mitad del siglo XX.
Nuevas atribuciones a Vicente Carducho, Giordano, Domingo Martínez y Mengs en el gabinete de dibujos y estampas del MNAC (Barcelona)
Authors: Bassegoda Bonaventura
Published: November 2022

Se propone aquí por vez primera la autoría de ocho dibujos de antiguos maestros, entre los que destacan los cinco originales de Anton Raphael Mengs, uno de ellos preparatorio para una obra clave de su carrera: el Parnaso de la Villa Albani de Roma, llevado a cabo en 1761.
Ciudades, complejos y arquitecturas para el descanso obrero: ensayos de Educación y Descanso en Alicante (España)
Authors: Carcelén González Ricardo
Published: November 2022

En los años cincuenta y principios de los sesenta, la Obra Sindical Educación y Descanso en España asumió el difícil reto de organizar el descanso y las vacaciones de los trabajadores del país. Aunque es en ese periodo cuando se llevó a cabo la ejecución de los principales conjuntos y ciudades de vacaciones para trabajadores de Educación y Descanso, el trabajo tiene por objetivo contrastar la hipótesis de la existencia de nuevos proyectos inéditos promovidos durante los últimos años del periodo franquista. Como resultados, se ha documentado la existencia de un proyecto para una ciudad de vacaciones para trabajadores agrícolas en Guardamar del Segura (Alicante), que nunca llegaría a ejecutarse como tal; y un Complejo Sindical de Turismo Social en Torrevieja (Alicante), desarrollado como alternativa al modelo ciudad de vacaciones de Educación y Descanso. El trabajo concluye valorando el abandono definitivo de estos modelos de organización de las vacaciones obreras en favor de otras fórmulas más competitivas.
Canvases in Conversation: Charles Amédée Philippe Van Loo’s Paintings for the Private Dining Room of King Frederick II of Prussia
Authors: Kulka Rahul
Published: November 2022

This article explores three little-studied paintings that Charles Amédée Philippe Van Loo produced for Frederick II (‘the Great’) of Prussia’s private dining room at the Potsdam City Palace in 1750. The group, which is today on display at the nearby Neues Palais, comprises a canvas representing Queen Dido’s banquet from Virgil’s Aeneid, as well as two smaller works depicting the pilgrimage to Cythera and a fête champêtre. Frederick’s dining rooms were a crucial stage for his self-fashioning as a roi philosophe. It was here that he and his illustrious inner circle of courtiers cultivated a brand of sociability that was unique amongst Europe’s princes in that it proudly professed the spirit of free discussion (as long as politics remained off the table and disagreement with the king was expressed moderately). In these spaces, paintings played a crucial role as mirrors and engines of conversation. Why did he choose these particular subjects and what kinds of conversations might the paintings have given rise to? Focusing on the centrepiece, Dido’s banquet, I argue, firstly, that the painting exemplifies Frederick’s ambitions as a literary man and roi philosophe. Secondly, I suggest that it is linked to Voltaire’s arrival in Prussia in the summer of 1750 and testifies to the writer’s intimate relationship with the Duchess of Maine, whose Feast of Dido and Aeneas by François de Troy served as a model for Van Loo’s canvas. Frederick must have known of and presumably appreciated this reference to the famous tastemaker from Sceaux. The study closes with a brief discussion of the Feast of Dido’s afterlife in the decorative arts of Frederick’s court, which underscores the painting’s importance for the king.
E-nose: A low-cost fruit ripeness monitoring system
Authors: Tyagi Pankaj , Semwal Rahul , Sharma Anju , Tiwary Uma Shanker , Varadwaj Pritish
Published: November 2022

All fruits emit some specific volatile organic compounds (VOCs) during their life cycle. These VOCs have specific characteristics, by using these characteristics fruit ripening stage can be identified without destructing the fruit.
In this study, an application-specific electronic nose device was designed for monitoring fruit ripeness.The proposed electronic nose is cost-efficient and does not require any modern or costly laboratory instruments. Metal oxide semiconductor (MOS) sensors were used for designing the proposed electronic nose. These MOS sensors were integrated with a microcontroller board to detect and extract the meaningful features of VOCs, and an artificial neural network (ANN) algorithm was used for pattern recognition. Measurements were done with apples, bananas, oranges, grapes, and pomegranates. The designed electronic nose proved to be reliable in classifying fruit samples into three different fruit ripening stage (unripe, ripe, and over-ripe) with high precision and recall. The proposed electronic nose performed uniformly on all three fruit ripening stages with an average accuracy of ≥ 95%.
The development of an employee value proposition framework for the South African water board sector
Authors: Theys Ndoyisile A. , Barkhuizen Emmerentia N.
Published: November 2022

Orientation: The South African water board sector plays an essential role in providing water and basic sanitary needs to the country. Yet the sector faces drastic talent shortages required to deliver its service mandate.Research purpose: The primary purpose of this study was to develop an employee value proposition (EVP) framework for the South African water board sector.Motivation for the study: Research on EVPs within the public sector is scarce. Employee value propositions are essential to attract, engage and retain scarce skills.Research approach, design and method: A qualitative research approach was followed. Semistructured interviews were used to collect the data from talent management stakeholders from nine water boards (n = 9). A constructive grounded theory method was applied to analyse the data.Main findings: The findings showed that EVPs received limited priority within the water board sector. The water board sector offered various financial awards, benefits, training and development opportunities to employees. In addition, the participants perceived a positive institutional culture and employment brand. The water boards thus already had fundamental building blocks available to integrate into a compelling EVP.Practical/managerial implications: The findings of this research emphasise the importance of management commitment towards creating a compelling EVP that will attract and retain those talented individuals who are of value to the strategy implementation of the South African water boards sector.Contributions/value-add: This research presents an original EVP framework that can be used as a guideline to manage workplace talent more effectively to achieve strategic government objectives.
A presumptive case of cutaneous emergomycosis in a female patient with HIV – Maseru, Lesotho
Authors: Madani Waheeba M.H. , Grayson Wayne
Published: November 2022

Emergomycosis is a recently described emerging opportunistic fungal infection among individuals living with HIV, in whom it is a cause of significant mortality and morbidity. This article retrospectively reports on a presumptive case of extensive cutaneous emergomycosis in a young immunocompromised patient from Lesotho. The histopathological features on skin biopsy were in keeping with emergomyces infection. The lesions responded to treatment with amphotericin B and oral fluconazole.Contribution: This case contributes to the existing evidence that as an emergent opportunistic infection, emergomycosis is possibly widespread in Africa but the true extend of the disease is not fully defined. This is further aggravated by the diagnostic difficulty as a result of limited resources in some areas in the region.