bluuebunny/crossref_metadata_2025 huggingface dataset:
A modelling approach to assess the impact of land mining on marine biodiversity: Assessment in coastal catchments experiencing catastrophic events (SW Brazil)
Authors: MAGRIS RAFAEL Almeida , Marta-Almeida Martinho , Monteiro Jose Alberto , Ban Natalie
Published: January 2019

Analysis that link hydrological processes with oceanographic dispersion offer a promising approach for assessing impacts of land-based activities on marine ecosystems. However, such an analysis has not yet been customised to quantify specific pressures from mining activities on marine biodiversity including those from spillages resulting from tailing dam failure. Here, using a Brazilian catchment in which a tailing dam collapsed (Doce river) as a case study, we provide a modelling approach to assess the impacts on key ecosystems and marine protected areas subjected to two exposure regimes: (i) a pulse disturbance event for the period 2015-2016, following the immediate release of sediments after dam burst, which witnessed an average increase of 88% in sediment exports; and (ii) a press disturbance phase for the period 2017-2029, when impacts are sustained over time by sediments along the river’s course. We integrated four components into impact assessments: hydrological modelling, coastal-circulation modelling, ecosystem mapping, and biological sensitivities. The results showed that pulse disturbance causes sharp increases in the amount of sediments entering the coastal area, exposing key sensitive ecosystems to pollution (e.g. rhodolith beds), highlighting an urgent need for developing restoration strategies for these areas. The intensity of impacts will diminish over time but the total area of sensitive ecosystems at risk are predicted to be enlarged. We determined monitoring and restoration priorities by evaluating and comparing the extent to which sensitive ecosystems within marine protected areas were exposed to disturbances. The information obtained in this study will allow the optimization of recovery efforts in the marine area affected, and valuation of ecosystem services lost.
“You are Fake News”: Ideological (A)symmetries in Perceptions of Media Legitimacy
Authors: Harper Craig A. , Baguley Thom
Published: January 2019

The concept of ‘fake news’ has exploded into the public’s consciousness since the election of Donald Trump to the US presidency in late 2016. However, this concept has received surprisingly little attention within the social psychological literature. We present three studies (N = 2,275) exploring whether liberal and conservative partisans are motivated to believe fake news (Study 1; n = 722) or dismiss true news that contradicts their position as being fake (Study 2; n = 570). We found support for both of these hypotheses. These effects were asymmetrically moderated by collective narcissism, need for cognition, and faith in intuition (Study 3; n = 983). These findings suggest that partisans across the political spectrum engage with the ‘fake news’ label in a motivated manner, though these motivations appear to differ between-groups. Theoretical and practical implications are discussed.
Discipline, abjection, and poverty alleviation through entrepreneurship: a grounded-theoretical inquiry.
Authors: Castellanza Luca
Published: January 2019

Collective entrepreneurship has been found to alleviate extreme poverty by helping poor individuals integrate into their societies and overcome their multiple intertwined liabilities. We complement this line of inquiry by exploring the conditions under which group structures may instead reinforce economic and gendered poverty constraints. We conducted grounded-theoretical interviews with 104 women entrepreneurs operating in farming cooperatives and non-farm groups in war-torn South-West Cameroon. Analysing our data through a constitutive lens, we found that discipline, the extent to which rules determine and control individual behaviours, helps poor women overcome extreme economic constraints but prevents them from attaining prosperity and emancipation.
Class Inequality in Parental Childcare Time: Evidence from Synthetic Couples in the ATUS
Authors: LaBriola Joe , Schneider Daniel
Published: January 2019

The time that parents spend teaching and playing with their young children has important consequences for later life achievement and attainment. Previous research suggests that there are significant class inequalities in how much time parents devote to this kind of developmental childcare in the United States. Yet, due in part to data limitations, prior research has not accounted for how class inequalities in family structure, assortative mating, and specialization between partners may exacerbate or ameliorate these gaps. We match parental respondents within the American Time Use Survey to generate synthetic parental dyads, which we use to estimate, in turn, the contributions of family structure, assortative mating, and specialization to class gaps in parental time spent in developmental care of children aged 0-6. We find some evidence that accounting for class differences in family structure widens income gaps in total parental time in developmental childcare of young children. Further, we show that assortative mating of parents further contributes to educational gaps in developmental childcare, while specialization between partners does not offset these wider class divides. While the net effect of these three processes on income-based gaps in childcare time is more modest, accounting for these three processes more than doubles education-based gaps in total parental developmental childcare as compared to maternal time alone. Our findings from this novel empirical approach provide a more holistic view of the extent and sources of inequality in parental time investments in young children’s cognitive and social development.
Perlindungan Hukum terhadap Anak yang Melakukan Tindak Pidana Pencabulan pada Putusan No.2/pid.sus/2014PN.Mdn
Authors: Sidabutar Risna , Suhatrizal Suhatrizal
Published: January 2019

Legal Protection for Children Conducting Crimes of Harassment on Decision No.2 / pid.sus / 2014PN.Mdn

 
Legal protection, for children can be interpreted as an effort to protect the law on various rights and freedoms of children and various interests related to child welfare. So, all children are protected, including children who are dealing with the law (ABH). The purpose of protection is to ensure the full rights of children to live, grow and participate optimally in accordance with human dignity and dignity, and to be protected from violence and discrimination, in order to realize quality Indonesian children who are noble and prosperous. Criminal action is a term commonly used in Indonesian law, where the term criminal act emphasizes an action that includes the meaning of doing or acting actively and not doing passively which is closely related to an attitude of someone who acts or acts. The actions or actions referred to contain elements or unlawful nature of an existing legal rule that prohibits such actions so that these actions can be punished.
ANALYSIS KEPUTUSAN WISATAWANDALAM MENGUNJUNGI TEMPAT WISATA KALIWATU RAFTING DI KOTA BATU
Authors: Sukmawati Rery , Martaleni Martaleni
Published: January 2019

Dewasa ini pertumbuhan pariwisata industri semakin pesat diiringi dengan meningkatnya kebutuhan manusia yang tinggi. Tingginya tingkat kunjungan wisatawan mampu memberikan manfaat bagi Negara dan daerah tujuan wisata. Oleh karena itu perlu adanya presepsi wisatawan terhadap Daerah Tujuan Wisata untuk mencari suasana baru yang tidak didapatkan di daerah wisata lain.Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh motivasi, persepsi, kelompok referensi dan kualitas layanan terhadap keputusan berkunjung. Populasi dalam penelitian ini adalah pengunjung Rafting Kaliwatu di Kota Batu selama tahun 2016 dengan sampel penelitian sebanyak 99 orang. Teknik analisis yang digunakan adalah analisis regresi berganda dengan uji signifikan F dan t.Temuan penelitian menyatakan bahwa motivasi wisata, persepsi wisata, kelompok referensi kualitas layanan berpengaruh signifikan terhadap keputusan berkunjung baik secara parsial maupun simultan.

Kata kunci: motivasi, persepsi, kelompok referensi, kualitas layanan keputusan
Analisis Model BisnisUsahaCoffee Shop Melalui Kanvas Model Bisnis dan Peta Empati: Studi Kasus padaCoffee Shop di Malang
Authors: Utama Bagus Ibnu
Published: January 2019

Persaingan dalam industri kuliner saat ini semakin marak, khususnya coffee shop. Keberadaan coffee shop seakan menjadi gaya hidup yang menjadi tren di kalangan masyarakat modern. Potensi pertumbuhan yang pesat didorong oleh bertambahnya jumlah mahasiswa yang ada di kota Malang. Hal ini dapat menjadi peluang bisnis yang sangat baik sekaligus juga akan meningkatkan persaingan antar pelaku bisnis dalam industri ini. Pertumbuhan konsumen Coffee Shop diiringi juga oleh pertumbuhan pelaku bisnis. Hal ini menjadikan persaingan Potensi pertumbuhan yang pesat ini dapat menjadi peluang bisnis yang sangat baik sekaligus juga akan meningkatkan persaingan antar pelaku bisnis dalam industri ini. Pertumbuhan konsumen Coffee Shop diiringi juga oleh pertumbuhan pelaku bisnis. Hal ini menuntut para pelaku bisnis untuk dapat memenangkan konsumen di tengah persaingan yang ketat sekaligus mengatasi kendala-kendala yang bisa terjadi di kota Malang semakin ketat.

Observasi awal peneliti menunjukkan dua hal yang menjadi kekurangan dari pelaku bisnis Coffee Shop di kota Malang yaitu kurangnya wawasan mengenai konsumen dan model bisnis yang belum terencana. Subjek dalam penelitian ini adalah para pelaku bisnis Coffee Shop dan konsumen Coffee Shopdi kota Malang. Pengumpulan data dilakukan dengan wawancara dan observasi. Metode analisis data dilakukan dengan menganalisis kanvas model bisnis dari pelaku bisnis dan menganalisis peta empati konsumen Coffee Shop. Hasil penelitian yang dapat diambil dari penelitian ini, bahwa masih kurangnya analisis yang komprehensif dalam menyusun model bisnis seperti kanvas model bisnis dan peta empati konsumen oleh pelaku bisnis Coffee Shop di kota Malang.

Kata Kunci : Coffee Shop, kanvas bisnis model, peta empati
PENGARUH KEPEMIMPINAN DAN BUDAYA ORGANISASI TERHADAP KINERJA KARYAWAN (StudiPada Bank Central Asia KCP Singosari Malang)
Authors: Imron Moh.
Published: January 2019

Tujuan penelitian ini adalah untuk mengetahui pengaruh kepemimpinan dan budaya organisasi terhadap kinerja karyawan di Bank Central Asia KCP Singosari Malang, baik secara parsial maupun simultan serta untuk mengetahui variabel yang berpengaruh dominan.

Jenis penelitian ini explanatory research. Populasi dalam penelitian ini adalah seluruh karyawanBank Central Asia KCP Singosari Malang. Sampel dalam peneleitian ini diambil dengan teknik sensus sebanyak 40 orang karyawan. Data dikumpulkan melalui kuesioner. Kuesioner terlebih dahulu diuji dengan menggunakan pengujian validitas dan reliabilitas. Teknik analisis data menggunakan analisis regresi berganda dengan melakukan uji asumsi klasik terlebih dahulu. Analisis data dalam penelitian ini menggunakan program SPSS 18.

Hasil penelitian menunjukkan bahwa: i) kepemimpinan dan budaya organisasi terhadap kinerja karyawan di Bank BCA KCP Singosari Malang secara parsial; ii) kepemimpinan dan budaya organisasi terhadap kinerja karyawan di Bank BCA KCP Singosari Malang secara simultan; iii) kepemimpinan memiliki pengaruh yang dominan terhadap kinerja karyawan di Bank BCA KCP Singosari Malang.

Keterbatasan dalam penelitian ini adalah variabel yang digunakan sebagai prediktor kinerja karyawan hanya terdiri dari dua variabel bebas yaitu kepemimpinan dan budaya organisasi. Masih banyak variabel lainnya yang dapat digunakan sebagai prediktor terhadap kinerja karyawan.

Kata kunci: Kinerja Karyawan, Kepemimpinan, Budaya Organisasi, Bank.
Ending Tuberculosis by 2030: United Nations High Level Meeting Commitments
Authors: Ismail Farzana , Omar Shaheed Vally , Ismail Nazir Ahmed
Published: January 2019

Abstract not availableInternational Journal of Human and Health Sciences Vol. 03 No. 02 April’19. Page: 51-53
On the Concept of Ecological Solidarity. What Connects Animal Rights with the Rights of Human Beings?
Authors: Probucka Dorota
Published: January 2019

The article consists of two parts. In the first one, I discuss the idea of ecological solidarity, which is interpreted by me as solidarity sensu largo resulting from the sense of belonging to a community of living and suffering beings. In the second part of the article I answer the question: what connects animal rights with the rights of human beings? In my opinion, if the European civilisation did not develop a category of solidarity, there would be no concept of human rights, and without the category of eco-solidarity there would be no concept of animal rights.
Climate Change Mitigation Justice and the No-Harm Principle
Authors: Piguet Frédéric-Paul
Published: January 2019

When translated into concrete policy, any allocation of emissions leads to the attribution of emissions rights based on distributive justice (even if the policy was previously examined in terms of utilitarianism at the philosophical level). Consequently, the distributive justice approach legitimizes the corresponding amount of emissions. If a certain level of emissions can receive emissions rights, provided they are compatible with a certain emissions budget, to allocate emissions rights when the dangerous concentration level has been overshot could understate the need to preserve the functioning of a “balanced” climate system. From the perspective of Foucault’s archaeology of knowledge, and with the purpose of assessing the epistemology of climate justice, it will be possible to question the possible importation of the mode of production of norms of social law into climate mitigation justice. Additionally, it will be questioned whether the amount of anthropogenic emissions rights can be provided by “the laws of nature” and whether and how the no‑harm principle can contribute to the epistemological relevance of the narrative of climate justice.
“Because he’s worth it”: Heroization of the Male Rescuer in Retellings of the “Sleeping Beauty” Tale Typ
Authors: Kaczyńska Barbara
Published: January 2019

The paper discusses some retellings of the “Sleeping Beauty” tale type (ATU 410) ranging from the 14th to the 21st century: a chivalric romance, literary fairy tales, and films, both animated and live-action. The analysis focuses on the portrayals of the male rescuer figure. His heroization and idealization seem to be a relatively new addition to the “Sleeping Beauty” myth and constitute a strategy that allows to mitigate the savior-aggressor ambivalence of the character and the violence implicit in the tale.
Wizerunek męskości w japońskich podręcznikach do klasy pierwszej szkoły podstawowej
Authors: Czaplewska Sonia
Published: January 2019

Jednym z najważniejszych narzędzi, za pomocą których uczniowie pierwszej klasy szkoły podstawowej poznają świat, są podręczniki szkolne. Informacje zdobyte w okresie dojrzewania mogą silnie oddziaływać na poglądy o rzeczywistości prezentowane na późniejszych etapach życia.  Niniejszy artykuł stanowi próbę analizy japońskich podręczników w kontekście zawartego w nich wizerunku męskości. Za materiał badawczy posłużyły książki wykorzystywane od 2015 roku w pierwszym semestrze nauki. Jak pokazują wyniki analizy, obraz męskości zawarty w badanych podręcznikach opiera się przede wszystkim na takich cechach jak rodzinność i opiekuńczość. Ukazany jest zatem nowy wzorzec męskości, który stoi w opozycji do tradycyjnego wizerunku reprezentowanego przez figurę zapracowanego salarymana.
Ethnos jako podstawa tożsamości kulturowej
Authors: Mielicka-Pawłowska Halina
Published: January 2019

Identyfikacja z grupą etniczną lub narodową jest o tyle skomplikowanym zagadnieniem, że obejmuje szereg zjawisk decydujących o różnorodności kultur. Szczególnie istotny jest mechanizm oddzielający „swoich” od „obcych”, a więc konstytuujący wszelkie sfery aktywności, które z jednej strony są oczywistością kulturową, a z drugiej mogą być przyczyną wartościowania innych przez pryzmat tego, co jest możliwe do zaakceptowania. Stawiam tezę, że o tożsamości kulturowej decyduje ethnos, a dokładniej jego cztery elementy strukturalne : język, obyczaje, historia oraz religia. Stanowią one odrębne systemy, których porządek wynika z korelacji zachodzących na poziomie interpretacyjnym. Szczególnie ważna w tej strukturze jest religia, która zabarwia emocjonalnie pozostałe elementy wierzeniami w istnienie rzeczywistości pozaempirycznej, a sądy i przekonania obowiązujące w grupie etnicznej lub narodowej czyni podstawowymi dla ukonkretnienia tożsamości kulturowej.
Rytuały jako praktyki pamięci zbiorowej (wybrane problemy transmisji pokoleniowej)
Authors: Sroczyńska Maria
Published: January 2019

W artykule podjęto problematykę znaczenia rytuałów jako praktyk pamięci zbiorowej. Rytuały stanowią istotny wymiar pamięci przeszłości, a zarazem pas transmisyjny w podtrzymywaniu ciągłości pokoleniowej. Na płaszczyźnie empirycznej odwołano się do wybranych rezultatów badań socjologicznych, dotyczących rytuałów upamiętniania oraz obrzędów o charakterze patriotycznym, w których obok sacrum świeckiego niejednokrotnie pojawia się sacrum religijne, wzmacniające ich znaczenie. Podstawą refleksji były rezultaty badań własnych, przeprowadzonych wśród młodzieży maturalnej oraz jej rodziców pod koniec pierwszej dekady XXI wieku, oraz aktualnych badań ogólnopolskich.
Prawosławie w życiu gagauskiej społeczności w Mołdawii
Authors: Jesionek Wiktor Józef
Published: January 2019

Myślą przewodnią jest twierdzenie, że prawosławie pełniło i pełni nadal istotną rolę w życiu społeczności mołdawskich Gagauzów. Celem niniejszego tekstu jest ukazanie roli prawosławia, która zmieniała się w czasie, oraz omówienie wybranych zagadnień związanych z prawosławiem przy uwzględnieniu obecnego stanu rzeczy, dokonane w oparciu o obserwacje własne i literaturę przedmiotu. W toku rozważań zostaną przedstawione bądź zasygnalizowane takie zagadnienia jak: tło historyczne, znaczenie duchowieństwa, religijność, prawosławne święta, cmentarze, świątynie, prawosławie w przestrzeni publicznej oraz struktura organizacyjna cerkwi prawosławnej.
The Role of Religion in the Fate of the Armenian People
Authors: Sahakyan Armen Kolyayi
Published: January 2019

The article represents the role and significance of Christianity as a national religion and the Armenian Apostolic Church as a national church in the life of Armenia and the Armenian people. Taking into account the historical facts, the invaluable contribution of the Armenian Church to the preservation of the Armenian identity and the strengthening of the Armenian statehood are pointed out. Historical-chronological analysis of state-church relations is observed, considering it in the framework of modern period as one of priority issues of globalization concerning the national security of the republic.     

The article represents the results of a series of sociological researches revealing the religious perceptions of the Armenian youth, thus trying to show the role and significance of Christianity and the Armenian Apostolic Church among contemporary Armenian youth.
Pluralizm eksplanacyjny w minimalistycznej neurofilozofii Henrika Waltera a fundamentalna teoria świadomości
Authors: Tofilski Mateusz
Published: January 2019

Artykuł jest próbą analizy koncepcji minimalistycznej neurofilozofii autorstwa Henrika Waltera w kontekście dyskusji dotyczącej problemu psychofizycznego. Bezpośrednio związana z ową koncepcją teoria o „zróżnicowanej metafizyce” została w tekście powiązana z ideą pluralizmu eksplanacyjnego i ukazana jako metodologiczna alternatywa dla poszukiwania fundamentalnych teorii świadomości. Jednocześnie poza ewentualnymi zaletami metafilozoficznej refleksji podejmowanej w ramach minimalistycznej neurofilozofii zarysowane zostały jej podstawowe ograniczenia i problemy związane m.in. z uznaniem superweniencji za punkt łączący różnorodne stanowiska neurofilozoficzne.
Męczennica – roślina użytkowa i symboliczna
Authors: Tomczyk Przemysław Piotr
Published: January 2019

Męczennica to bardzo interesujący rodzaj roślin obecny w wielu sferach życia człowieka. Męczennice pochodzą z tropikalnych regionów obu Ameryk, obecnie niektóre z jej gatunków hodowane są w ciepłych regionach całego świata. Poszczególne gatunki uprawiane są ze względu na jadalne owoce, ze względów leczniczych czy ozdobnych. Nie sposób pominąć również znaczenia męczennicy w kulturze – badacze chrześcijańscy dopatrzyli się w elementach jej budowy morfologicznej narzędzi Męki Pańskiej. W niniejszej pracy przedstawiono historię odkrycia rośliny dla Europejczyków, charakterystykę rodzaju, elementy ekologii (mimikra), właściwości lecznicze, przegląd najczęstszych gatunków oraz znaczenie rośliny w symbolice chrześcijańskiej.
Évaluation de la qualité de la prescription d’antibiotiques dans les infections urinaires de l’adulte au service d’urgences
Authors: Bérard L.M.
Published: January 2019

Objectifs : De nombreux traitements anti-infectieux sont débutés dans les services d’urgences (SU). Nous avons étudié la qualité de la prescription d’antibiotiques dans le traitement probabiliste des infections urinaires (IU) au SU d’un centre hospitalier général français.

Matériels et méthodes : Nous avons conduit une étude rétrospective monocentrique du 1er janvier au 30 juin 2017. Tous les patients pour lesquels une IU a été diagnostiquée au SU ont été inclus. Les traitements hospitaliers et ambulatoires des IU ont été analysés au regard des recommandations de 2015 de la Société d’infectiologie française. Le critère principal d’évaluation a été le classement des antibiothérapies probabilistes en deux catégories : « conforme » ou « non conforme » à ce référentiel. Le critère secondaire d’évaluation a été l’adéquation du traitement antibiotique initial à la sensibilité des souches bactériennes identifiées.

Résultats : Cent quatre-vingt-onze patients ont été inclus : 99 pyélonéphrites (52 %), 18 prostatites (9 %), 48 cystites (25 %) et 26 infections urinaires de siège non précisé (14 %). L’âge moyen a été de 52 ans avec 26 % d’hommes et 74 % de femmes. Au total, 114 antibiothérapies (60 %) ont été considérées conformes aux recommandations. Des antibiotiques ont été prescrits par excès dans 35 cas. La souche identifiée n’était pas sensible au traitement instauré au SU dans neuf situations.

Conclusion : Cette étude met en exergue les difficultés pour la mise en application des recommandations en thérapeutique anti-infectieuse au SU dans 40 % des situations. Un rappel et une évaluation continue des bonnes pratiques de prescription des antibiotiques au SU sont nécessaires.
Analisis Potensi Kawasan Rawan Banjir Kota Kepanjen Menggunakan Sistem Informasi Geografis (SIG)
Authors: Pattiraja Agustinus Haryanto
Published: January 2019

Kota Kepanjen adalah Kota yang dipersiapkan menjadi Ibu Kota Kabupaten Malang, yang pemanfaatan lahan terus berkembangan dan dengan intensitas hujan yang cukup tinggi berdampak timbulnya genangan dan banjir. Penelitian ini bertujuan menganalisis potensi kawasan rawan banjir di Kota Kepanjen. Metode yang digunakan yaitu Sistem Informasi Geografis. Berdasarkan konsep analisis debit aliran Metode Rasional maka parameter penentu kawasan rawan banjir yang digunakan dalam kajian ini adalah intensitas hujan, kemiringan lereng, jenis tanah, dan tutupan lahan. Hasil analisis menunjukan bahwa kawasan yang berstatus sangat rawan pada kondisi eksisting dengan luasan sebesar 3,421 Km2 mengalami peningkatan seiring perubahan yang akan dilakukan terhadap Kota Kepanjen menjadi 4,54 Km2 , kawasan yang berstatus rawan pada kondisi eksisting dengan luasan sebesar 40,17 Km2 mengalami peningkatan seiring perubahan yang akan dilakukan terhadap Kota Kepanjen menjadi 42,01 Km2, kawasan yang berstatus aman pada kondisi eksisting dengan luasan sebesar 2,92 Km2 mengalami penurunan seiring perubahan yang akan dilakukan terhadap Kota Kepanjen menjadi 0,22 Km2.
Pemodelan Perubahan Penggunaan Lahan – Cellular Automata di Kecamatan Asemrowo, Kota Surabaya
Authors: Widodo Widiyanto Hari Subagyo , Imaduddina Annisaa Hamidah
Published: January 2019

Kecamatan Asemrowo memiliki perkembangan yang stagnan karena adanyapengaruh dari genang pasang air laut yang mengakibatkan penurunan nilai lahan (RDTRK UP Tambak Osowilangun, 2007). Kondisi struktur dan mofologi kota yang stagnan berpotensi untuk berubah karena adanya pembangunan pusat pertumbuhan baru yaitu Pelabuhan Teluk Lamong (Pelindo III). Penelitian ini bertujuan untuk memprediksi penggunaan lahan ke depan dengan mengakomodasikan faktor penghambat berupagenang pasang air laut dan faktor pendorong (Pelabuhan Pelindo III) menggunakan metode Markov – cellular automata.Markov- cellular automata adalah salah satu jenis kecerdasan buatan dengan dasar perhitungan iterasi pada data raster. Iterasi tersebut dilakukan pada data raster probabilitasperubahan penggunaan lahan yang diformulasikan dari multi-faktor pendorong perubahan penggunaan lahan dan penghambat perubahan penggunaan lahan. Jumlah piksel yangmenjadi acuan dalam proses iterasi dianalisis dengan menggunaan analisis Markov. Dalam merumuskan peta probabilitas perubahan penggunaan lahan digunakan metode regresi logistik dan jaringan saraf tiruan. Tahun akhir prediksi penggunan lahan adalah 2030.Hasil penelitian menunjukkan genang pasang air laut memiliki korelasi positif terhadap perubahan penggunaan lahan menjadi industri pergudangan, permukiman desa, dan tambakyaitu sebesar 21%, 20% dan 22%
Konsep Kampung Wisata Belanja Berkelanjutan Klaster Industri Kerajinan Mutiara, Emas dan Perak (MEP) di Kelurahan Karang Pule, Kecamatan Sekarbela, Kota Mataram
Authors: Sushanti Ima Rahmawati , Kurniawan Agus
Published: January 2019

Keberadaan klaster industri di Kota Mataram memberikan pengaruh sosial, ekonomi dan lingkungan terhadap kawasan permukiman sekitarnya (Sushanti, Ima R, 2015). Sesuai Rencana Tata Ruang Wilayah Kota Mataram tahun 2011 – 2031 klaster industri MEP di Kelurahan Karang Pule, Kecamatan Sekarbela ditetapkan sebagai kawasan pariwisata belanja.  Tujuan penelitian adalah menentukan konsep kampung wisata belanja dalam rangka penataan klaster industri dan kawasan permukiman sekitarnya yang terpadu, secara fisik, ekonomi dan sosial berdasarkan komponen perancangan. Hasil  penelitian adalah konsep  kampung wisata belanja berkelanjutan yang layak, produktif dan partisipatif mengintegrasikan potensi klaster industri dan kawasan permukiman sekitarnya di Kelurahan Karang Pule, Kecamatan Sekarbela, Kota Mataram.
Identifikasi Pengendalian Pemanfaatan Ruang Melalui Instrumen Insentif dan Disinsentif Pada Kawasan Pariwisata Pesisir di Pantai Amahami dan Ni’u
Authors: Wardenia Anggun , Hirsan Fariz Primadi
Published: January 2019

Pengendalian pemanfaatan ruang pada kawasan pariwisata pesisir pantai Amahami dan Ni’u perlu dilakukan mengingat daerah tersebut merupakan salah satu kawasan strategis pariwisata dan kawasan strategis perekonomian yang adaS di Kota Bima, dengan dilakukannya suatu pengendalian diharapkan pemanfaatan ruang yang ada pada kawasan tersebut dapat berjalan sesuai dengan rencana pola ruang Rasanae Barat, salah satu instrumen yang tepat untuk digunakan selain peraturan zonasi adalah instrumen insentif dan disinsentif, dimana instrumen insentif diberikan kepada pemerintah ataupun masyarakat yang taat dan tertib terhadap tata ruang, sedangkan disinsentif diberikan kepada pemerintah ataupun masyarakat yang tidak tertib atau melanggar tata ruang.
KAJIAN PERUBAHAN FISIK SPASIAL KAWASAN URBAN FRINGE DI KECAMATAN AMPENAN KOTA MATARAM
Authors: Sushanti Ima Rahmawati , Imansyah Nahrul Hayat , Susanti Febrita , Mahendra Yusril Ihza , Ridha Rasyid
Published: January 2019

Penelitian ini bertujuan mengetahui sejauh mana perubahan fisik yang terjadi akibat adanya perkembangan Kota Mataram dari tahun 2010 sampai tahun 2017 dan mengevaluasi implementasi RTRW Kota Mataram terhadap perubahan fisik spasial Kawasan Urban Fringe Kota Mataram khususnya di Kecamatan Ampenan. Metode penelitian menggunakan pendekatan deskriptif kualitatif- kuantitatif dengan menggunakan analisis matriks konsistensi dan dikombinasikan dengan analisis spasial untuk membantu dalam analisa pemetaan. Hasil dari kajian luasan perubahan fisik spasial Kecamatan Ampenan dari tahun 2010 sampai tahun 2017 adalah +80,49 Ha atau 8,59% dari total luas wilayahnya, dimana konversi lahan yang dominan terjadi yaitu berupa lahan pertanian (sawah) berubah fungsi menjadi lahan terbangun perkotaan (permukiman dan terbangun non permukiman). Sedangkan hasil evaluasi konflik ruang antara RTRW dengan Penggunaan Lahan pada tahun 2010 dan 2017, diperloleh bahwa pada tahun 2010 terdapat 47.61 Ha (5.04 %) yang bersifat bertentangan/inkonsisten, 123.38 Ha (13.06 %) yang bersifat nertal, dan 773.93 Ha (81.90 %) yang bersifat sesuai/konsisten. Sedangkan pada tahun 2017 terdapat 75.41 Ha (7.98 %) yang bersifat bertentangan/inkonsisten, 75.70 Ha (8.01 %) yang bersifat netral dan 793.81 Ha (19.88 %) yang bersifat sesuai/konsisten. Sehingga dapat disimpulkan bahwa, secara umum implementasi kegiatan pemanfaatan serta pengendalian ruang di Kecamatan Ampenan masih dikategorikan dalam kondisi aman dan berjalan dengan cukup baik
ANALISIS PERUBAHAN PENGGUNAAN LAHAN DI KAWASAN PERDESAAN EKS TRANSMIGRASI KECAMATAN WASILE KABUPATEN HALMAHERA TIMUR
Authors: Husin Muchlis , Herwangi Yori
Published: January 2019

Kawasan perdesaan Cemara Jaya dan Batu Raja merupakan salah satu kawasan perdesaan eks transmigrasi di Kabupaten Halmahera Timur, Provinsi Maluku Utara yang saat ini telah berkembang pesat, baik dari aspek sosial ekonomi maupun perkembangan fisik. Berbagai perkembangan tersebut menyebabkan meningkatnya perubahan penggunaan lahan, terutama perubahan dari lahan non produktif menjadi lahan produktif. Untuk itu diperlukan analisis terkait penggunaan lahan untuk menggambarkan dinamika perubahan yang terjadi. Analisis yang digunakan adalah analisis overlay yang dilakukan secara multi periode yakni tahun 1982, 1990, 2000, 2010, dan 2017. Hasil penelitian ini menunjukkan adanya perubahan penggunaan lahan di kawasan perdesaan Cemara Jaya dan Batu Raja dari penggunaan lahan yang didominasi hutan menjadi penggunaan lahan yang didominasi sawah.
STRATEGI PROMOSI DALAM PENINGKATAN JUMLAH MAHASISWA BARU FAKULTAS ILMU SOSIAL DAN ILMU POLITIK UNIVERSITAS MUHAMMADIYAH MATARAM
Authors: Abdullah Ibrahim , Lubis Lubis
Published: January 2019

Abstrak: Tujuan dari penelitian ini untuk mengetahui strategi promosi yang di lakukan oleh Fakultas Ilmu Sosial Dan Ilmu Politik Universitas Muhammadiyah Mataram dalam upaya rekrutmen dan peningkatan jumlah mahasiswa baru sebagai salah satu indikator kemajuan Universitas termasuk Fakultas. FISIPOL merupakan salah satu fakultas yang ada di Universitas Muhammadiyah Mataram. Untuk dapat memotivasi calon mahasiswa maka strategi promosi yang merupakan ujung tombak dari suatu perencanaan pemasaran sangat di butuhkan untuk mencapai tujuan. Keberhasilan FISIPOL dalam meningkatkan jumlah mahasiswa tidak terlepas dari strategi promosi. Strategi dan metode promosi yang dimaksud adalah rencana untuk penggunaan secara maksimal dari komponen seperti iklan, promosi institut,  promosi kualitas, biaya dan sarana prasarana. Metode analisis data digunakan analisis kualitatif dari data dan informasi yang diperoleh dari informan diolah dan di simpulkan maknanya sebagai hasil laporan akhir penelitian ini. Hasil akhir dari penelitian ini menunjukan penggunaan metode promosi 4P+S yaitu product, price, place, promotion dan satisfaction menunjukan hasil yang positif dan signifikan dalam meningkatkan  jumlah mahasiswa baru khususnya di FISIPOL Universitas Muhammadiyah Mataram.Kata Kunci: Strategi; Promosi; Mahasiswa; Fisipol
ANALISIS KESULITAN DALAM MEMAHAMI KEMAMPUAN VERBAL DALAM MEMBUAT MODEL MATEMATIKA PROGRAM LINEAR
Authors: Mahsup Mahsup
Published: January 2019

Abstrak:: Penelitian ini bertujuan untuk mengetahui Faktor–faktor yang mempengaruhi kesulitan mahasiswa dalam memahami kemampuan verbal pada materi Program Linear mahasiswa semester IV Prodi Pendidikan Matematika FKIP UM Mataram. Penelitian ini menggunakan metode deskriptif kualitatif. Dalam penelitian ini subjek penelitian sebanyak 4 mahasiswa yang ditentukan berdasarkan hasil tes kemampuan numerik Program Linear. Data dikumpulkan dengan metode tes. Tes soal digunakan untuk menganalisis kesulitan mahasiswa dalam menyelesaikan soal Program Linear. Metode analisis yang digunakan adalah analisis deskriptif kualitatif. Berdasarkan hasil tes dan analisis jawaban mahasiswa adapun faktor-faktor yang mempengaruhi kesulitan mahasiswa dalam kemampuan verbal adalah mahasiswa kurang mampu membuat model matematika program linear, menguji titik-titik kritis dan menentukan nilai maksismum atau minimum.    Kata Kunci: Kesulitan Belajar; Kemampuan Verbal; Kemampuan Numerik
FAKTOR- FAKTOR YANG MENYEBABKAN STATUS GIZI KURANG PADA BALITA DI WILAYAH KERJA PUSKESMAS SAIL PEKANBARU TAHUN 2016
Authors: Irianti Berliana
Published: January 2019

Abstract:  Nutrition status is a health condition of a person's body or a group of people caused by consumption, absorption and the use of nutrients. Factors leading to undernourishment in under-five children: Overcrowded birth, socioeconomic, ignorance of food and health relationships, prejudice against certain food items, overabundance of certain types of food, infectious diseases. The purpose of this study to determine the factors that cause underweight nutritional status in infants in the working area of sail health center in 2016. Quantitative research type and descriptive research design. The location of the research was conducted in the working area of Sail Health Centre and the time of the research on February 15-20, 2016. The population of mothers who had under-five children with less nutritional status in Sail Health Centre were 20 cases and all were used as research samples. The research instrument uses check list and data collection techniques using primary data. The result showed that from 20 respondents, the majority of knowledge factors of mothers who have under five children with low nutritional status are low knowledge as many as 11 people (55%), and the majority of factors of economic level of parents are low as many as 12 people (60%) and majority of birth distance factor which is too tight as many as 12 people (60%). From the results of this study, the researcher hopes to become input material of health institution by improving mother's knowledge about nutrient status less on toddler through counseling from health officer and providing supplementary food for the toddler
THE CONCEPTUAL AND CLINICAL PROBLEMS OF PARANEOPLASTIC SYNDROME IN ONCOLOGY AND INTERNAL MEDICINE
Authors: Bilynsky B T , Dzhus M B , Litvinyak R I
Published: January 2019

Symptomatology of oncological diseases consists not only of local symptoms caused by the primary malignancy or its metastases, but also by general systemic signs that are not directly connected with the tumor. These symptoms are mostly associated with autoimmunity or endocrine influences. In many cases, the source of paraneoplastic syndromes (PNS) is unknown. Nearly 15% of oncological patients demonstrate these syndromes but it is diagnosed much more rarely. The survey of the numerous PNS is offered. The significance of the PNS differs for oncologists and other physicians who encounter it in their practice. The reason of those differences, as well as the connection between PNS and cancer toxicity is discussed. The experience of antitoxic therapy (hemosorption, lymphosorption, enterosorption) used in our clinic in the previous years is overviewed.
HORMONAL IMPACT ON TUMOR GROWTH AND PROGRESSION
Authors: Reznikov A
Published: January 2019

In this review, current knowledge of hormones impact on prostate, breast and endometrium cancer growth and transition to hormone therapy resistant phenotype is summarized. A special consideration is given to genetic alterations and hormone responsive signa ling pathways. Estrogen, androgen and progesterone are the key drivers in these cancer variants. Hormone receptors and their interplay with plenty of growth factors generated by the tumor microenvironment contribute greatly to carcinogenesis and cancer cell proliferation. The tumor cell plasticity that could explain a loss of responsiveness to hormone deprivation therapy and aggressive course of the diseases has been addressed.
ACONITINE-CONTAINING AGENT ENHANCES ANTITUMOR ACTIVITY OF DICHLOROACETATE AGAINST EHRLICH CARCINOMA
Authors: Pyaskovskaya O N , Boychuk I V , Fedorchuk A G , Kolesnik D L , Dasyukevich O I , Solyanik G I
Published: January 2019

Significant variability of anticancer efficacy of dichloroacetate (DCA) stimulated an active search for the agents capable to enhance it antitumor action. Therefore, the aim of this work is the study of capability of aconitine-containing antiangiogenic agent BC1 to enhance anticancer activity of DCA against Ehrlich carcinoma. Materials and Methods: DCA (total dose was 1.3 g/kg of b.w.) and BC1 (total dose was 0.9 mg/kg of b.w.) were administered per os starting from the 2nd and 3rd days, respectively (8 admini strations for each agent). Antitumor efficacy of agents was estimated. Lactate level, LDH activity and the state of mitochondrial electron transport chain in tumor cells as well as phagocytic activity and reactive oxygen species (ROS) production of tumor-associated macrophages (TAM) were studied. Results: Combined administration of DCA and ВС1 resulted in 89.8% tumor growth inhibition (p < 0.001), what is by 22.5% (p < 0.05) higher that that of DCA alone. This combined treatment was accompanied with a decrease of lactate level in tumor tissue by 30% (p < 0.05) and significant elevation of LDH activity by 70% (p < 0.01). Increased level of NO-Fe-S clusters and 2-fold reduction of Fe-S cluster content were revealed in tumor tissue of mice after DCA and BC1 administration. It was shown that combined therapy did not effect TAM quantity and their phagocytic activity but stimulated ROS production by TAMs by 78% (p < 0.05) compared to this index in control animals. Conclusion: Antiangiogenic agent ВС1 in combination with DCA considerably enhances antitumor activity of DCA via significant decrease of Fe-S-containing protein level resulted from substantial elevation of nitrosylation of these proteins.
COMBINED USE OF HAEMOSTATIC SYSTEM INDICES FOR EVALUATION OF UPPER RESPIRATORY TRACT CANCER PROGRESSION
Authors: Klys Y G , Gryn N V , Verevka S V
Published: January 2019

Aim: To analyze whether comprehensive assessment of haemostatic system components, in particular, indices of coagulation and fibrinolytic systems along with functionally related proteins, could be indicative of upper respiratory tract (URT) cancer progression. Materials and Methods: Indices of coagulation and fibrinolytic systems along with functionally related proteins, in particular, trypsinlike amidolytic activity, trypsin-like proteolytic activity, thrombin-like amidolytic activity, elastase-like amidolytic activity, fibrinolytic activity, potential amidolytic plasmin activity, content of fibrinogen, antithrombin III, α1-proteinase inhibitor, and α2-macroglobulin, and prothrombin time were evaluated in blood plasma of patients with URT cancer of II (n = 10) and III (n = 25) stages with the use of routine biochemical methods. Results: For both groups of patients with URT cancer there have been shown notable differences for the majority of the studied indices, especially the indexes of proteolytic activities, from these of healthy donors, and in the case of URT cancer of III stage they reached statistical significance. In contrary, the changes in the content of antithrombin III, α1-proteinase inhibitor, and α2-macroglobulin were insignificant. In both groups of patients significant increase of fibrinogen content has been registered, while the content of soluble fibrinogen didn’t change. Also, in both groups of patients there a significant increase of potential activity of plasminogen was documented, while clot lysis time was significantly increased only in patients with III stage URT cancer. Multifactorial analysis of haemostatic system indices evidenced for efficacy of their combined use for evaluation of URT cancer progression risk. Conclusion: Combined use of fibrinogen and α2-macroglobulin content and the level of amidolytic thrombinlike activity could serve as an indicator of URT cancer progression.
70TH ANNIVERSARY OF THE LVIV SCIENTIFIC SCHOOL OF ONCOLOGY
Authors: Bilynsky B T , Shparyk Ya V , Mryglotsky M M , Lukavetskyy N O , Volodko N A , Litvinyak R I
Published: January 2019

Contemporary development of scientific thought is fostered not by separate people but is a purposeful activity of a group of likeminded people armed with progressive ideas and modern technical equipment. Such schools appeared and work actively in the majo rity of research and educational establishments, clinics, and universities. The Lviv school established in 1945 by Professor H.P. Kovtunovych and developed by Professor A.I. Hnatyshak and his disciples can serve as an example of a successful school of oncology that continues its activity and yields scientific results. This school appeared not out of the thin air. Medieval Lviv could boast of the first university on the territory of the present-day Ukraine. Many discoveries and endeavors that made a beneficial impact on the development of medicine in Eastern Europe were made in this city. For historical reasons, the city of Lviv used to belong to different state formations (Austria-Hungary, Poland, the USSR; now it is a part of Ukraine), which could not but reflect on the staffing of doctor-researchers. This process acquired a special intensity in 1939–1945 when the research staff of the university changed substantially. Then, in 1945, H.P. Kovtunovych, the disciple of the prominent oncologist N.N. Petrov, came to Lviv and brought the ideas of St.-Petersburg oncology to the Lviv ground. The Lviv school was influenced by the two times Nobel Prize winner Marie Skłodowska Curie, who facilitated the initiation of oncological radiology in Lviv. The article contains data on research done by the disciples of Professors H.P. Kovtunovych and A.I. Hnatyshak. The first ever teaching chair of oncology in the USSR was founded in Lviv (1966), as well as the first Ukrainian hospice — an institution for palliative care for the oncological patients. The Lviv oncology center is one of the biggest and best-equipped oncology centers in Ukraine. An organic combination of theory and clinical practice has always been the guiding principle of the Lviv school of oncology. Presently, the Lviv school of oncology unites six doctors of sciences, a large collective of educators and researchers, as well as practitioners of the center of oncology. The school maintains close scientific and practical ties with oncologists of Ukraine as well as with leading oncological centers of Europe and America.
COMPREHENSIVE META-ANALYTICAL SUMMARY ON HUMAN PAPILLOMAVIRUS ASSOCIATION WITH HEAD AND NECK CANCER
Authors: Bychkov V A , Nikitina E G , Ibragimova M K , Kaigorodova E V , Choinzonov E L , Litviakov N V
Published: January 2019

An etiological role of high risk human papillomavirus (HPV) in the development of cervical cancer has been well established. Hence, attention of researchers has been focused on the role of HPV in pathogenesis of other malignancies, such as head and neck cancers. An analysis of epidemiological data on the prevalence of HPV infection among healthy people and patients with precancerous lesions and/or cancer is an important step in understanding the role of HPV in head and neck carcinogenesis. More and more data demonstrate the impact of HPV infection on disease outcome. HPV­positive patients have been shown to have better responses to radiotherapy and better overall and disease­free survival than HPV­negative patients. This review presents data of the metaanalysis based on a large number of original studies on HPV prevalence in patients with precancerous lesions and in patients with oral, oropharyngeal and laryngeal cancers as well as findings on the impact of HPV infection on survival of these patients.
FOREWORD TO THE SPECIAL ISSUE “THE CHORNOBYL NUCLEAR ACCIDENT: THIRTY YEARS AFTER”
Authors: Chekhun V F
Published: January 2019

The 2016 Special Issue of Experimental Oncology is dedicated to the 30th anniversary of the Chornobyl disaster, medical and biological consequences of which still have a negative impact on the health of the population of Ukraine and other affected countries.
MODIFYING EFFECTS OF 5-AZACYTIDINE ON METAL-CONTAINING PROTEINS PROFILE IN GUERIN CARCINOMA WITH DIFFERENT SENSITIVITY TO CYTOSTATICS
Authors: Chekhun V F , Lozovska Yu V , Naleskina L A , Borikun T V , Burlaka A P , Todor I N , Demash D V , Yalovenko T M , Zadvornyi T V , Pavlova A O , Storchai D M , Lukianova N Yu
Published: January 2019

Aim: To assess the influence of the treatment with 5-azacytidine (5-aza) on the profile of metal-containing proteins and factors of their regulation in Guerin carcinoma cells in vivo. Materials and Methods: The study was conducted on Wistar rats transplanted with wild-type Guerin carcinoma (Guerin/WT) and its strains resistant to cisplatin (Guerin/CP) or doxorubicin (Guerin/Dox). Animals were distributed in 6 groups treated with 5-aza and control animals without treatment. 5-Aza was injected by i.v. route (1 injection in 4 days at a dose of 2 mg/kg starting from the 4th day after tumor transplantation, 4 injections in total). Ferritin levels in blood serum and tumor tissue were measured by ELISA, transferrin and free iron complexes — by low-temperature EPR, miRNA-200b, -133a and -320a levels and promoter methylation — by real-time quantitative reverse transcription polymerase chain reaction. Results: The study has shown that 5-aza treatment caused demethylation of promoter regions of fth1 and tfr1 genes in all studied Guerin carcinoma strains. 5-Aza treatment resulted in a significant decrease of ferritin levels in tumor tissue (by 32.1% in Guerin/WT strain, by 29.8% in Guerin/Dox and by 69.1% in Guerin/CP). These events were accompanied by 3.5-fold and 2-fold increase of free iron complexes levels in tumor tissue of doxorubicin and cisplatin resistant strains, respectively. Also, 5-aza treatment resulted in significantly elevated levels of miR-200b, -133a, 320a expression in tumor tissue. After 5-aza treatment, ferritin levels in blood serum of animals with Guerin/Dox were increased by 23.9%, while in Guerin/Wt and Guerin/CP they were decreased by 17 and 16%, respectively. Conclusion: Alterations of epigenetic regulation upon in vivo treatment with 5-aza change the levels of metal-containing proteins due to DNA demethylation and altered miRNA expression profiles in Guerin carcinoma cells.
QUEST AND ACHIEVEMENTS: on the 60th birth anniversary and 20 years of directorship of Vasyl Fedorovych Chekhun
Authors: Board Editorial
Published: January 2019

In November 2016 Director of R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the NAS of Ukraine, Editor-in-Chief of “Experimental Oncology” Academician of the NAS of Ukraine Vasyl Chekhun celebrated his 60th birth anniversary.
PARTHENOLIDE REDUCES GENE TRANSCRIPTION OF PROSURVIVAL MEDIATORS IN U937 CELLS
Authors: Mohammadi S , Zahedpanah M , Nikbakht M , Shaiegan M , Hamidollah Ghaffari S , Nikugoftar M , Rahmani B , Hamedi Asl D
Published: January 2019

In acute myeloid leukemia (AML) the functional abnormalities of osteopontin (OPN), NF-kB, PI3K/AKT/mTOR/PTEN pathway or β-catenin have been considered. Aim: To analyze the response of U937 cells to parthenolide (PTL) through the involvement of expression of OPN protein, RelB, AKT1, mTOR, PTEN and β-catenin genes. Materials and Methods: The U937 cells were treated with PTL at concentrations of 4 μM (IC25) or 6 μM (IC50) and with OPN siRNA for MTT assay and colony forming assay. Western blot analysis using antibodies against OPN was performed with lysates of PTL-treated cells. Quantitative real-time polymerase chain reaction was performed using primers for OPN siRNA, RelB, AKT1, mTOR, PTEN and β-catenin. Results: PTL reduces OPN protein level and down-regulates RelB mRNA in U937 cell line. Suppression of OPN with siRNA increases the cytotoxic effects of PTL. Also, mRNA expression of AKT1, mTOR, PTEN, and β-catenin decreases with PTL or OPN siRNA. Conclusion: Sensitivity of U937 cells to PTL can be associated with the reduction in expression of prosurvival mediators.