bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of mutation in the coding regions of FAM83H and ENAM genes in patients with imperfect enamel (Amelogenesis Imperfecta)
Authors: Najafi Shamsoulmolouk , Roudgari Hasan , Palizgir Reyhaneh , Naderifard Marjan , Meighani Mohammad Eerfan
Published: January 2021

Introduction: Tooth enamel is a precious and highly mineralized tissue in the human body. Amelogenesis Imperfecta (AI) is a developmental, evolutionary and hereditary disease presents with the rare abnormal formation of enamel that affects the primary and secondary dentition. The molecular base of the incomplete quinizium together with clinical manifestation suggest that AI may result from mutations in the FAM83H and ENAM genes. In this study, we aimed to evalu- ate the association between Amelogenesis Imperfecta and mutations in the FAM83H and ENAM genes in 18 Iranian families with AI in dominant and non-syndromic form.
Materials and Methods: 18 Iranian families with at least 1 patient with Amelogenesis Imperfecta were included in this case study and were examined for related specific manifestations and also, 10CC of blood was taken from each patient followed by PCR and genome sequence for genetic alterations in FAM83H and ENAM. Genome sequences were analyzed using CLC software and CLC Sequence Viewer was used to compare them with reference sequences in the RefSeq database at the NCBI later were discussed together with clinical manifestations for each patient.
Results: All patients showed a mutation in the exon 5 of FAM83H gene in nucleotide rs56148058C/T which converted Serotonin to Aspartin. In two patients carried a mutation in the nucleotide rs546809055A/G that changed Leucine to Phenylalanine. None of patients showed sig- nificant alteration in the ENAM gene.
Conclusion: This study indicates that FAM83H gene plays an import role in incidence of Amelogenesis Imperfecta in Iran.
SOCIAL CHANGE AND DEVELOPMENT: CONNECTING MODERNIZATION AND FAMILY INSTITUTION ON QUALITATIVE GROUNDS
Authors: Imran  , Alam Intikhab , Khan Khattak Mamoon , Jawad Muhammad , Aurangzeb Khan Muhammad
Published: January 2021

Purpose of the study: The qualitative study has been designed with the primary objective to find the impact of and link between modernization and the changing facets of the family institution. The study also focused on exploring the various dimensions of modernization responsible for bringing change in the family institution. Methodology: The data was collected from the different nature of potential participants from all seven tehsils of district Swat, Pakistan. In-depth interviews (IDIs) and focus group discussion (FDG) were incorporated as research instruments, whereas an interview guide was used under IDIs and FGDs. The collected data were processed under the frame of qualitative research approach wherein after transcribing, and coding of the data themes was identified. Main Findings: The thematic analysis of family structure, patriarchy, decision making in the family, and ways of communication exposed that due to modernization, the family institution is under continuous change. Applications of this study: The research results can be applied to such studies that focus on changes in family institutions, communities with similar socio-cultural characteristics. Novelty/Originality of this study: The unique feature of this study is that such kinds of topics have been very rarely investigated in the context of Pakistani society and especially in Pakhtun culture.
THE EXISTENTIAL ALIENATION OF THE FEMININE SELF IN THIS HOUSE OF CLAY AND WATER BY FAIQA MANSAB
Authors: Saeed Amna , Rehman Aiman
Published: January 2021

Purpose of the study: The present study aims to analyze the text This House of Clay and Water (2017) by Mansab, through the Existentialist Feminist lens in the light of Simone de Beauvoir’s theory as explained in her revolutionary work, The Second Sex (2009). The purpose of the study is not only to highlight women’s oppression/ othering in marriage due to patriarchy but also to mark the role of the ‘husband’ as crucial to the understanding of women’s emotional abandonment in marriage.

Methodology: The study is qualitative and uses a descriptive analysis of the selected text. The method of literary analysis used in the text is based on a close reading of the narrative description and events of alienation of the identity persona of the protagonist in the text.

Main Findings: The present study draws on Simone de Beauvoir’s ideas about how women are treated as others by the male subject in marriage resulting in a feeling of frustration, identity loss alienation, and existential crisis. Moreover, the role of the husband is crucial to avoid this crisis in women after marriage.

Application of the study: This study can have many applications in various fields. The study demonstrates the impacts of social and cultural stereotypes on women as well as the role of patriarchy and resulting alienation. This study can have many applications in gender and feminist studies. This study can also be helpful in the academic setting for research purposes especially in feminism, gender studies, and female existentialism.

The novelty of the study: The present study demonstrates how the protagonist feels entrapped and suffocated in her home, forced to live a life of false hope due to the impositions placed on her by her parents, her husband, her in-laws, and the patriarchal society which resultantly creates a feeling of alienation. The study concludes how dissuading a woman from her true self and forcing her to exist as an object results in a feeling of dissatisfaction, existential crisis, and alienation. The selected text has not been explored through the lens of Existential Feminism before.
Análisis económico de la responsabilidad del Estado por construcción de obras públicas
Authors: Martínez Benavides Nicolás Enrique
Published: January 2021

El presente trabajo estudia, desde el Análisis Económico del Derecho, la responsabilidad del Estado por construcciones públicas. A la luz de los criterios de eficiencia económica, de Pareto y Kaldor Hicks, el escrito concluye que la indemnización de perjuicios en dichos eventos constituye una mejora paretiana, pues con la construcción se mejoró el bienestar de la comunidad y nadie se perjudicó porque quien inicialmente había sido afectado recibió la respectiva compensación. Adicionalmente, se realizan recomendaciones normativas con el fin de lograr que la compensación se realice de manera administrativa mediante un acuerdo con el afectado, toda vez que es la manera ideal para que se internalicen las externalidades negativas derivadas de la construcción de obras públicas y porque cuando la compensación se hace por la vía judicial se presenta una pérdida de eficiencia económica debido a los gastos en que incurren tanto el Estado como el particular afectado.
Los sesgos cognitivos en la función de control fiscal: la naturaleza humana, un aspecto a considerar
Authors: Rojas Arias Juan Camilo
Published: January 2021

Los estudios sobre la influencia de los caminos heurísticos y sesgos cognitivos en el desarrollo de las funciones públicas, específicamente en el desarrollo del control y vigilancia fiscal, son de desarrollo ínfimo en Colombia. En consecuencia, el objetivo del presente artículo es realizar un análisis descriptivo sobre los principales hallazgos que marcan el estudio sobre la arquitectura de las decisiones humanas, en el marco del control y vigilancia fiscal en Colombia. Para este objetivo, se realizará especial énfasis en decantar la estructura del control y vigilancia fiscal y algunos resultados de su gestión que permitan detectar los efectos invisibles de algunos caminos heurísticos y sesgos sobre el proceso de adopción de decisiones en desarrollo del control fiscal.
Sobre la protección contra abusos entre empresarios. Las cláusulas abusivas y el abuso de posición de dependencia económica
Authors: Contreras Delgado Santiago Andrés
Published: January 2021

El presente texto aborda la problemática de las asimetrías presentes en los contratos B2B y los potenciales abusos entre empresarios, desde siempre considerados como contratantes en igualdad de condiciones, dado el carácter profesional de las partes. El artículo se enfoca, por un lado, en el abuso de la situación de dependencia económica y, por el otro, en las cláusulas abusivas; dos figuras específicas que los ordenamientos pueden adoptar para la corrección de las condiciones negóciales inequitativas en los contratos B2B, su explicación y abordaje normativo, con un especial análisis del caso colombiano. Identificando cuál es el estado del arte de ambas instituciones y concluyendo la necesidad de seguir explorando el horizonte de posibilidades que los sistemas normativos tienen para proveer soluciones a las situaciones abusivas entre empresarios.
Green bonds as a source of financing pro-environmental actions in Poland
Authors: Hajdys Dagmara
Published: January 2021

Climate changes and progressing environmental pollution enforce undertaking various actions of the global range. Implementation and execution of pro-environmental programs require appropriate financing. In 2007 a new instrument, referred to as green bonds, appeared in the market. Since that, a systematic and dynamic development of this segment of capital market has been observed. The development takes place in terms of values, a number of instruments and a number of issuers. In 2016 a pioneering issuance of green bonds issued by the Polish government appeared in the market. The objective of the study is to characterize green bonds issued by the Polish government to finance pro-environmental actions against the background of the global green market of debt securities. The hypothesis accepted in the study stated that the development of green bonds in Poland is determined by the development of the global green market of debt securities and is a response to a need for intensification of expenditure on pro-environmental programs.
Determinanty recesji na rynku pożyczek pozabankowych w Polsce
Authors: Waliszewski Krzysztof
Published: January 2021

Zaostrzenie regulacji w zakresie detalicznej działalności kredytowej banków (rekomendacja T KNF) doprowadziła do dynamicznego wzrostu sektora pożyczek pozabankowych w Polsce. Obok segmentu tradycyjnego (off-line) pożyczek udzielanych w domu i w punktach stacjonarnych – własnych i partnerskich, np. poprzez pośredników finansowych w związku z rozwojem nowoczesnych technologii w finansach konsumenckich (fin-tech), powstał i dynamicznie rozwinął się segment pożyczek udzielanych zdalnie (on-line, digital lending, Lendtech). W okresie dynamicznego wzrostu pozabankowego sektora pożyczkowego w życie weszło szereg regulacji o charakterze ostrożnościowym i w zakresie ochrony konsumenta–pożyczkobiorcy, a największe instytucje pożyczkowe od lutego 2016 r. zostały objęte tzw. podatkiem bankowym. Jednak statystyki rynku pożyczkowego za 2019 r. wskazują, że z miesiąca na miesiąc dynamika sprzedaży pożyczek pozabankowych spadała, aby w końcu roku osiągnąć ujemne wartości (ok. –3%), oznaczające w praktyce stan recesji tego rynku. Celem artykułu jest identyfikacja determinant zaobserwowanej w 2019 r. recesji rynku pożyczek pozabankowych. W artykule wykorzystano literaturę przedmiotu, na którą składają się akty prawne, artykuły naukowe, raporty i dane statystyczne.
Establishment of irrigation schedule for rice cropping seasons in the Long Xuyen Quadrangle, Vietnam using Cropwat model
Authors: Dang Truong An
Published: January 2021

This study is conducted to determine the appropriate irrigation water amount for three main cropping seasons (TMCS) of rice in the Long Xuyen Quadrangle, Vietnam (LXQ). In the work, the Cropwat crop model was used to calculate irrigation water amount for winter-spring (WS), summer-autumn (SA) and autumn-winter (AW) crops based on meteorological data collected in period from 1998 to 2017. Simulation results carried out that WS crop was needed more irrigation water than SA and AW crops. The highest irrigation water requirement (IWR) of WS, SA and AW crops occurred on development stage with approximately values 207.1 mm, 205.8 mm and 102.3 mm respectively. The results showed that the proposed model is successfully applied to define crop water requirement (CWR) and irrigation requirement in the context of climate change leading to irrigation water scarcity.
Comparison of some physiological responces to salinity and normal conditions in Sugar Beet
Authors: Khorshid A.M. , Moghadam F.A. , Bernousi I. , Khayamim S. , Rajabi A.
Published: January 2021

This study was carried out in the Agricultural Research Center of West Azerbaijan, Iran in 2016. In this research, variations in different physiological and yield traits measurement of total dry weight, shoot fresh weight, shoot dry weight, root fresh weight, root dry weight, relative water content, relative water loss, root length, leaf area, root/shoot ratio, specific leaf weigh, sodium content, potassium content and proline were investigated in normal and saline condition. The results indicated that in saline condition, total dry weight, root fresh weight, shoot dry weight, root/Shoot ratio, specific leaf weight, root length, proline and Na content were increased and the other traits were decreased. Study of correlation of traits showed that most significant difference between the two conditions was observed for the root/shoot ratio, so that, this trait has negative significant relation with total dry weight, shoot fresh weight, shoot dry weight, root fresh weight, root dry weight, relative water content, leaf area, root length, specific leaf weight in saline condition, but in normal condition correlation is positive and significant only in the total dry weight, root fresh weight, shoot dry weight and root dray weight and was not significant in the other traits. Step-wise regression analysis for total dry weight as dependent variable revealed that in normal condition, root fresh weight, shoot fresh weight and Na content expound of 93.1% and in saline condition root fresh weight, root length, Na content and proline explicate of 81.3% of total variation exist in total dry weight. Therefore, it is suggested to consider different traits in breeding programs for normal and saline conditions.
Effect of integrated seed treatments on growth, seed yield and quality parameters in black gram [Vigna mungo (L.) Hepper]
Authors: Narayanan G. Sathiya , Prakash M. , Kumar V. Rajesh
Published: January 2021

Pulses are one of the most important legume crops in India contributing significantly high quality protein. Among the legumes, black gram (Vigna mungo L. Hepper), is an important legume crop in our country belonging to the family leguminoceae. The low productivity in pulses may be due to the fact that they are normally grown in marginal lands with inadequate soil moisture and poor fertility status. To increase yield under these circumstances, integrated seed treatment is given as a presowing treatment. Hence, a study was attempted to find out the influence of integrated seed treatments on growth and yield parameters in black gram. The seeds of black gram cv VBN 4 were subjected to various seed treatments and treated seeds along with the control were evaluated for their seed quality, growth, gas exchange and yield parameters both in laboratory and field trials. The study revealed that seeds fortified with MgSO4 + polykote + carbendazim + dimethoate + bioinoculant (Pseudomononas fluorescens) + Rhizobium + Azophos + pelleting with DAP recorded higher seed yield and other parameters when compared to control.
Impacts of irrigation frequency and nitrogen rate on productivity, quality, nutrient uptake and nutrient use efficiencies of late sown wheat (Triticum aestivum L.)
Authors: Kumar Mukesh , Pannu R.K. , Kumar Amit , Singh Bhagat , Dhaka A.K.
Published: January 2021

An experiment was conducted at CCS Haryana Agricultural University, Hisar during rabi 2010-11 and 2011-12, consisting of three irrigation frequencies viz. one irrigation at CRI, two irrigations at CRI and heading and four irrigations at CRI, late tillering, heading and milking in main plots and five nitrogen levels (0, 50, 100, 150 and 200 kg N/ha) in sub-plots in strip plot design with four replications. Grain yield and NUE increased significantly with increased irrigation levels. Increase irrigation frequency increased the N (33.4 and 31.3 %), P (42.2 and 42.3 %) and K (26.7 and 25.1 %) uptake over one irrigation during 2010-11 and N (16.0 and 15.9 %), P (19.4 and 20.7 %) and K (11.2 and 13.5 %) during 2011-12. Increased nitrogen dose increased the protein content, hectolitre weight, sedimentation value and grain yield over control. Maximum and minimum nutrient uptake was recorded with 200 and 0 kg N/ha.
Simulation of phenology, total nutrient uptake and grain yield of wheat under different irrigation and nitrogen application managements in Hisar, India using the DSSAT-CSM-CERES-Wheat model
Authors: Kumar Mukesh , Pannu R.K. , Singh Bhagat
Published: January 2021

The purpose of this study was the calibration and validation of DSSAT-CSM-CERES-Wheat model (v4.5) for wheat in Hisar conditions. The DSSAT-CSM-CERES-Wheat model was calibrated with the field experimental data of rabi 2010-11 having 3 levels of irrigation (I1-one irrigation at crown root initiation [CRI], I2- two irrigations at CRI and heading and I3- four irrigations at CRI, late tillering, heading and milking) and 5 nitrogen levels (0, 50, 100, 150 and 200 kg N/ha) and validated with data of experiment rabi 2011-12 conducted at Hisar (29°10’ N and 75°46’ E). The model performance was evaluated using average error (Bias), root mean square error (RMSE), normalized root mean square error (nRMSE), index of agreement (d-stat) and coefficient of determination (r2), and it was observed that DSSAT-CSM-CERES-Wheat model was able to predict the phenology, total nutrient uptake and grain yield of wheat with reasonably good accuracy. The simulated results were within the permissible limit of the error (error % less than ±15).
Yield, quality, nutrient and water use efficiency of tomato as affected by different fertigation rates through drip irrigation system
Authors: . Ankush , Sharma S.K.
Published: January 2021

An experiment was carried out to study the impact of drip fertigation in tomato crop at RCA, MPUAT, Udaipur during rabi season 2015-16 in split plot designed with three irrigation schedules [100 (I1), 75 (I2) and 50% PE (I3) through drip] and five fertilization schedules [100% RDF (F1), 75% RDF (F2), 75% RDF + 2 foliar spray of 1% urea phosphate (F3), 50% RDF (F4), 50% RDF + 2 foliar spray of 1% urea phosphate (F5)]. Higher number of nodes per plant (21.20 and 19.89) and yield (169.03 and 186.38 q/ha) were registered with treatments receiving drip irrigation at 75% PE and 75% RDF through fertigation + 2 foliar spray of 1% urea phosphate, respectively. Quality characteristics were enhanced with combined use of I2F3 treatment. The highest water use efficiency i.e. 26.37 ka/ha-cm was recorded under I3F3 treatment and fertilizer use efficiency with I2F5 treatment combination (165.78, 254.31 and 381.46 kg/kg NPK, respectively).
An improved method of seed germination testing in Kabuli chickpea
Authors: Gowda Basave , Naik A. Krishna , . Rakesh , Mathad C. , Ganiger B.S. , Lokesh G.Y. , Raghu B.N. , . Rekha
Published: January 2021

An experiment was conducted during 2014-2015 to standardize the seed testing method in Kabuli chickpea MNK-1 by number of seeds and number of germination papers. Among the different testing methods 25 seeds per replication recorded highest seed germination percentage (91.58%), less number of fresh un-germinated seeds (1.91%), abnormal seedlings (4.00%), diseased seeds (2.33%) and significantly higher seedling vigour index-I and II (2215 and 6863), among the number of germination papers used 2+1 as in between paper method(Bottom 2 and one paper above) recorded significantly higher germination percentage (92.12%), less number of fresh un-germinated seeds (1.41%), abnormal seedlings (3.66%), diseased seeds (2.33%) and significantly higher seedling vigour index-I and II (2463 and 6900), when compared to other. Irrespective of number of germination paper and seeds used however, interaction of 25 seeds per replication and 2+1 between paper method of seed germination testing showed significantly germination percentage (96.50%), less number of fresh un-germinated seeds (0.00%), abnormal seedlings (1.00%), diseased seeds (1.00%) and significantly higher seedling vigour index-I and II (2844 and 7792) followed by 50 seeds per replication.
Evaluation of wheat genotypes (Triticum aestivum L.) for assessment of character association, path coefficient and cluster analysis
Authors: Kumar Anuj , Gaurav Shailendra Singh , Singh Tejbir , Thapa Ravi Singh
Published: January 2021

Thirty wheat genotypes (Triticum aestivum L.) were evaluated for 11 morphological and yield trait for analysis of character association (phenotypic and genotypic correlation coefficient), path analysis and cluster analysis. The experiment was conducted during rabi seasons of 2014-2015 in a randomized block design with three replication. Days to 50% heading showed positive and significant correlation with flag leaf area and number of spiklet per ear; flag leaf area showed positive and significant correlation with 1000 grain weight; Plant height showed positive and significant correlation with spike length; spike length showed positive and significant correlation with 1000 grain weight. Phenotypic path analysis showed biological yield and number of grain per spike had highly positive and direct effect on grain yield. Direct and highly positive effect on grain yield was shown by number of productive tillers, plant height, spike length, number of spikelet per spike genotypic path coefficient. Biological yield and grains yield per plant show highly positive and direct effect on yield with number of productive tillers, plant height, number of spikelet per spike and spike length. In cluster analysis the intra cluster distance ranged from 1.61 (cluster II) to 2.37 (cluster III and VI ). Thus the member of cluster II were least divergent and similarly the member of cluster III and IV were most divergent The maximum inter cluster distance was between cluster II and III followed by cluster IV and V , cluster VI and III and cluster VI and V that order therefore the accessions grouped in the five pair of cluster may be considered as most divergent.
Isolation, characterization and growth response study of chlorpyrifos utilizing soil bacterium Pseudomonas putida JR16
Authors: Rank Jalpa K. , Nathani Neelam M. , Hinsu Ankit T. , Joshi Anjali U. , Shekar Mootapally Chandra , Kothari Ramesh K.
Published: January 2021

Agricultural pesticides are one of the indispensable materials used to meet increasing demand of food crops. Consequently, pesticides find their way to various ecosystems resulting in detrimental pollution problems. Chlorpyrifos is a predominantly used organophosphorus pesticide leading to harmful effects including abnormal cell division. Scientific attempt to eliminate these contaminants from the environment using biodegradation approach has been appreciated. Soil bacteria capable of utilizing chlorpyrifos are potential bioremediation candidates. In context to the same, the present study isolated six bacteria growing in presence of chlorpyrifos as sole carbon source from agricultural soils. The obtained bacterial isolates characterized based on their morphological characteristics, biochemical reactions were found to be Pseudomonas spp. JR16, Pseudomonas spp. J1, Pseudomonas spp. J2, Pantoea spp. J3, Enterobacter spp. J4 and Kocuria spp. J5. Among these, the most potential of them viz., Pseudomonas spp. JR16, was further proceeded for molecular identification and was observed to be the Pseudomonas putida JR16. The influence of different chlorpyrifos concentration, various carbon sources, metals sources, temperature and pH on the growth of Pseudomonas putida JR16 was assessed for developing optimum conditions for on field application of the strain for biodegradation of chlorpyrifos.
Identity and Leisure Time: Aspiration of Muslim Influencer on Instagram
Authors: Nur Aini Rezki Putri
Published: January 2021

Abstrak

Tulisan ini menganalisis segmentasi identitas dan aspirasi melalui wacana waktu luang yang diusung oleh kalangan influencer Muslim Indonesia sebagai representasi atas upaya negosiasi masyarakat kelas menengah Muslim baru terhadap orientasi pemahaman keagamaan dan budaya populer dalam kerangka modernisasi. Keniscayaan atas munculnya perbedaan pemahaman keagamaan diantara para influencer Muslim tersebut pada akhirnya mempengaruhi mereka dalam merepresentasikan setiap wacana yang diusung melalui media baru, termasuk waktu luang. Waktu luang yang perannya seringkali diabaikan, menjadi salah satu penentu identitas gaya baru Muslim menengah saat ini dengan sengaja dipamerkan melalui berbagai platform media sosial. Kajian ini penting dilakukan untuk melihat sejauh mana segmentasi akibat identitas dan aspirasi baru melalui waktu luang yang ingin disalurkan oleh kalangan influencer Muslim tersebut secara masif di media sosial, khususnya Instagram. Kajian ini dilakukan melalui studi netnografi dengan didukung oleh berbagai literatur relevan  yang ada. Hasil dari kajian menunjukkan terdapat dua tren segmentasi besar di kalangan influencer Muslim saat ini melalui pewacanaan waktu luang di media sosial, mereka adalah  committed Muslim influencer dan muslimist influencer dimana masing-masing memiliki perbedaan identitas dan aspirasi baru dalam mewacanakan waktu luang berdasarkan pemahaman keagamaan yang saling kontradiksi diantara keduanya.
Konsep Al-Qur’an tentang Kualitas Hidup Manusia sebagai Seorang Khalifah dan Maslahatnya terhadap Makhluk Lainnya
Authors: Rusmanto
Published: January 2021

Rusmanto, Konsep Al-Qur’an tentang Kualitas Hidup Manusia sebagai Seorang Khalifah dan Maslahatnya terhadap Makhluk Lainnya, Tesis, Studi Qur’an/ Aqidah dan Filsafat Islam, Pascasarjana UIN Sulthan Thaha Saifuddin Jambi, 2020.

Fokus penelitian ini adalah pada ayat-ayat alquran yang berbicara tentang Manusia Sebagai Seorang Khalifah di muka bumi ini, Selanjutnya akan menelaah ayat-ayat alquran tersebut tentang Maslahatnya atau kebaikan-kebaikan yang bisa ditimbulkan manusia ketika Allah sebutkan dia sebagai seorang khalifah terhadap Makhluk Lainnya yaitu alam semesta beserta isinya. Adapun tujuan dari penelitan ini adalah : 1). Untuk mengetahui Kualitas Manusia itu menurut Konsep Alquran. 2). Untuk mencari Kualitas Hidup Manusia Sebagai Seorang Khalifah menurut Konsep Alquran. 3). Untuk mendalami Maslahat Kualitas Hidup Manusia Sebagai Seorang Khalifah bagi Makhluk Lainnya Menurut Konsep Alquran.

Penelitian ini merupakan Riset Kepustakaan (Library Research) dengan menerapkan pengambilan data secara langsung melalui hasil bacaan, mengumpulkan data sebanyak mungkin, memperkaya analisis, mengumpulkan data-data akurat dan mengutip buku-buku yang sesuai dengan bahasan penelitian, serta mengidentifikasi data-data sesuai langkah-langkahnya, kemudian dilanjutkan dengan menganalisis data menggunakan metodologi metode tafsir tematik (Maudhu’i).

Penelitian ini menghasilkan tiga kesimpulan yaitu: 1). Kualitas  Manusia menurut konsep Alquran diantaranya; Pertama, Kualitas Iman. Kedua, Kualitas Kecerdasan atau Intelegensi. Ketiga, Kualitas Emosi (Rasa). Keempat, Kualitas Budi dan Sosial. 2). Menurut konsep alquran, kualitas hidup manusia sebagai seorang khalifah yaitu memiliki kualitas hidup lebih dibandingkan manusia umumnya baik dari segi fisik maupun non fisik nya. 3). Maslahat Kualitas Hidup Manusia sebagai Seorang Khalifah bagi Makhluk Lainnya Menurut Konsep Alquran, yaitu dia akan membawa kebaikan, memberi manfaat, dan menjadi sebab terjadinya peningkatan kualitas hidup, pertambahan nilai menjadi sebab terpeliharanya nilai luhur.

Kesimpulan dalam penelitian ini adalah menurut konsep alquran kualitas hidup manusia sebagai seorang khalifah yang diharapkan oleh Allah swt adalah mereka yang memiliki kualitas hidup lebih dibandingkan dengan manusia umumnya dari tiga indikator dalam diri manusia, yaitu dari otaknya, hatinya, dan amal sholehnya. Sehingga akan bisa menjalankan tugasnya sebagai khalifah di muka bumi yang diharapkan oleh Allah SWT.

 

Kata Kunci : Konsep Alquran, Kualitas Hidup Manusia, Khalifah, Maslahat.
Implementasi Metode Tahsin Al Husna dalam Pembelajaran Jarak Jauh pada Masa Pandemi Covid-19 di SDIT Al Kahfi
Authors: Rahmawan Muhammad Arif , Mushlihin  , Siregar Khairil Ikhsan , Wajdi Firdaus
Published: January 2021

This study aims to describe and analyze the implementation of the Al Husna method in learning tahsin at SDIT Al Kahfi Ciracas via distance learning mechanism. It seeks to answer the following questions, how was the preparation for distance learning tahsin Al-Quran using the Al Husna method, the implementation of distance learning tahsin Al-Quran using the Al Husna method, the evaluation of learning in distance learning tahsin using the Al Husna method. It also will describe the use of media in distance learning tahsin using the Al method Husna. This research used a descriptive analysis method using a qualitative approach, which was carried out from October to November 2020.  Primary data collection took place at SDIT Al Kahfi Ciracas, East Jakarta. Data collection techniques include observation and interviews at SDIT Al Kahfi Ciracas, East Jakarta. Based on the results of observations and interviews conducted by researchers, distance learning Al-Quran tahsin using the Al Husna method at SDIT Al Kahfi, is implemented quite well. This can be seen from the stages in distance learning tahsin using the Al Husna method. Starting from the preparation and planning that is sufficiently well prepared with the administration of learning planning, preparation in terms of the capacity of teacher resources, as well as preparation of facilities and infrastructure to support distance learning. But, lesson planning design section was incomplete. Then, this study also shows that the implementation of tahsin distance learning using the Al Husna method was in accordance with the learning plan. Furthermore, it can also be seen from the evaluation of learning held in distance learning tahsin using the Al Husna method worked as expected.
LAS TIC, UNA OPORTUNIDAD DE PARTICIPACIÓN CIUDADANA EN LOS GOBIERNOS SUBNACIONALES
Authors:   Universidad ESAN, Franciskovic Jubitza , Hamann Antonieta , Miralles Francesc
Published: January 2021

La presente investigación explora el uso de las tecnologías de información y comunicaciones en la participación ciudadana de los gobiernos subnacionales con alta digitalización. Para el análisis de los datos se utilizó la teoría fundamentada, se realizaron entrevistas semiestructuradas a representantes de los gobiernos subnacionales en Lima Metropolitana y representantes de instituciones públicas y privadas. Los resultados resaltan que los Gobiernos Subnacionales, siguiendo las normas estatales de Gobierno electrónico, ofrecen numerosos y modernos servicios a través de sus portales web; sin embargo,estos son subutilizados por los ciudadanos.
LIBERTAD RELIGIOSA, DE CULTO Y DE CONCIENCIA EN LA POLÍTICA PÚBLICA DE BOGOTÁ
Authors:   Universidad de La Salle, Martínez Posada Jorge Eliécer , Torregrosa Jiménez Norhys Esther , Reyes Sánchez Gina Marcela , Jiménez Hurtado José Luis , Torres Serrano Juan Manuel , Torregrosa Jiménez Rodolfo ,   Corporación Universitaria Republicana
Published: January 2021

En Colombia, la Constitución Política de 1991 estableció como derechos fundamentales de los ciudadanos las libertades religiosa, de culto y de conciencia. El Estado, a través de los años, ha desarrollado los alcances de los mencionados derechos hasta llegar a la formulación de la política pública de libertad religiosa y de cultos en el 2018. Si bien, desde el punto de vista jurídico, el Estado tiene como funciones el reconocimiento, la garantía y la protección de los derechos para que los ciudadanos puedan hacer ejercicio pleno de ellos en todas sus manifestaciones, se identifica que al momento de poner en práctica el ordenamiento jurídico, las normas presentan problemas en su aplicación. El presente trabajo busca problematizar el Decreto 93 del 12 de febrero de 2018 expedido por la Alcaldía Mayor de Bogotá en el contexto de la libertad religiosa como derecho y del lugar de la religión en el espacio público, a partir de la pregunta ¿Cómo orienta la política pública los derechos fundamentales de libertad religiosa, de culto y de conciencia en la ciudad de Bogotá?
DEL NACIONALISMO HACIA EL POSITIVISMO JURÍDICO COMPARADO
Authors:   Universidad Libre, Garzón Buenaventura Edgar Fabián
Published: January 2021

La cimentación de un espacio jurídico y político común entre los Estados busca la solución por la vía diplomática, el arreglo consensual y el reconocimiento del otro. Esto genera nuevas fuentes que oxigenan la validez del derecho; es decir, las aparentes contradicciones entre los Estados se resuelven gracias a la construcción de un marco jurídico internacional entre ellos. Lo anterior supone una mutación de la dimensión nacional formal del positivismo metodológico, dirigido hacia un positivismo jurídico comparado. Esto es el reflejo de la fuerza detonante emanada desde el Derecho Penal Internacional, el Derecho Comunitario, el Derecho Internacional de los Derechos Humanos, entre otros, los cuales actúan como causales de una nueva conceptualización de las fuentes del derecho entre la interpretación auténtica en manos del legislador, rechazando el pluralismo normativo y la interpretación constitucional, para la aplicación de una responsabilidad, no solo de índole nacional, sino internacional, dando una connotación hacia un derecho cosmopolita y trasnacional. En efecto, se ha superado la añeja discusión del Derecho Internacional bajo la perspectiva del soft law, se ha avanzado hacia la facultad de la que dispone cualquier ciudadano para impetrar una petición o consulta sobre su derecho cosmopolita, a raíz de la internacionalización del derecho que ha generado reglas, normas, directrices y precedentes en el ágora del derecho público por una justicia global.
Composição bromatológica de silagens de milho comerciais produzidas no Brasil
Authors: Faria T.R.F. , Pinese F. , Gimenes F.M.A. , Demarchi J.J.A.A. , Campus F.P. , Premazzi L.M. , Mattos W.T. , Gerdes L.
Published: February 2021

Objetivou-se fazer a análise exploratória dos resultados bromatológicos e uso de modelos para estimativa de nutrientes digestíveis totais das amostras de silagem de milho gerados a partir de 12 anos de análises comerciais do banco de dados do Laboratório de Nutrição Animal do Instituto de Zootecnia (IZ), em Nova Odessa, SP, Brasil. Como critério, utilizou-se dados de amostras de silagens de milho sem nenhum tipo de aditivos presentes no banco de dados do laboratório, somando 220 amostras nos períodos de 2004 a 2015 e agrupados em quatro triênios. Estes foram caracterizados quanto à sua composição bromatológica através da análise estatística descritiva, correlações de Pearson e pela utilização de modelos de estimativas de NDT calculado através de quatro modelos de equações: uma da Universidade de Clemson, uma segundo Harlan e duas segundo Kearl (1 e 2). O valor nutricional das amostras de silagens de milho mostrou-se de qualidade mediana, com valores de FDN (49,2 a 57,2% da MS) acima do ideal. Todas as equações puderam ser utilizadas na estimativa do NDT (variação de 54,3 a 67,0 nos triênios) sendo que a de Kearl 1 e Clemson apresentaram a maior e a menor variação entre os triênios, respectivamente. O aumento do valor nutritivo e de NDT nos triênios 3 e 4 indica melhoria na qualidade da silagem.
Features of polymerization of methylmethacrylate using a photocatalyst – the complex oxide RbTe1.5W0.5O6
Authors: Semenycheva Liudmila Leonidovna , Chasova Victoria , Matkivskaya Julia , Fukina Diana , Koryagin Andrey , Belaya Tatiana , Grigoreva Alexandra , Kursky Yuri , Suleimanov Evgeny
Published: January 2021

Radical polymerization of methylmethacrylate in an aqueous emulsion was carried out using the complex oxide RbTe 1.5 W 0.5 O 6 as a photoinitiator under visible light irradiation with λ= 400-700 nm. Studies of the process and reaction products using modern methods of physical and chemical analysis (GPC, IR, NMR, etc.) have shown that several directions of monomer transformations occur simultaneously in the reaction mixture. Polymethylmethacrylate, produced in the organic phase and characterized by Mn ~ 140-145 kDa, is a result of polymerization initiation by a hydroxyl radical formed due to complex transformations of electron-hole pairs during irradiation of the photocatalyst. Moreover, the interaction of the hydroxyl radical with OH groups on the complex oxide RbTe 1.5 W 0.5 O 6 surface and the subsequent formation of oxygen-centered radicals lead to grafting polymer macromolecules onto the photocatalyst surface. In addition, methylmethacrylate is able to oxidize to a cyclic dimer with terminal double bonds and then form a polymer with cyclic dimer links due to coordination by double bonds on the complex oxide RbTe 1.5 W 0.5 O 6 surface. The high activity of the hydroxyl radical made it possible to obtain the graft copolymer PMMA-pectin by grafting the polymer product onto the surface of the natural polymer-pectin. Comparison of the sponge morphology of the graft copolymer PMMA-pectin and the initial pectin samples using the scanning electron microscopy method showed a noticeable difference in their structural and topological organization. This fact is especially interesting in terms of studying the properties of the graft copolymer as a material for the scaffolds.
Paleo-earthquake Evidence and Earthquake Recurrence for Düzce Fault, Turkey
Authors: Komut Tolga , Karabudak Ersin
Published: January 2021

Paleoseismological trenching was performed along the Düzce fault providing some preliminary insight about its seismogenic behavior. Dating was based on radiocarbon analysis of peat samples collected from the trenches and suggested seven earthquakes have occurred since 1740 BC. Integrating date constraints of events exposed in the trenches suggests a periodical earthquake recurrence model. According to a linear sequential event serial that has minimum misfit determined by considering the probability curve limits of the sample dates, the earthquake recurrence interval is between 384 and 460 years (or possibly between AD 394 and 400). A probability curve was also calculated for the date of the last earthquake (1999 Düzce earthquake) considering the probability distributions of sample dates based on the same event serial. This probability-distribution-based method, similarly, predicted that the 1999 Düzce earthquake occurred between 1933–2005 (± 36 years) with a 68 % probability. After this verification. Using this method, it was estimated that the next earthquake along the Düzce fault has a 68 % probability of occurring between 2328–2392. According to this calculation, the earthquake recurrence interval is about 391 ± 34 years with a 68 % probability and the AD 967 historical earthquake likely ruptured the Düzce fault. Assuming an average slip of 350 cm (the average slip of the 1999 earthquake), the slip rate was estimated to be between 8.7–11.2 mm/a.
3BDO Inhibits proliferation, epithelial–mesenchymal transition (EMT) and stemness via suppressing survivin in human glioblastoma cells
Authors: wang zhaotao , Li yongping , liu minyi , chen danmin , ji yunxiang , xing zhou , wang yezhong
Published: February 2021

BackgroundGlioblastoma (GBM) is a tumor of the central nervous system carries an extremely poor prognosis. Unfortunately, it also is the most frequently encountered tumor in this region. These tumors arise from glioblastoma stem cells (GSCs), which are glioma cells that are known to possess high degrees of stemness. GBM invades through the process of EMT, which features loss of cell differentiation and polarity. Survivin is a type of apoptotic inhibitor that has been characterized in several malignancies such as glioma. Normal tissues rarely express survivin. On the other hand, 3-benzyl-5-((2-nitrophenoxy) methyl) dihydrofuran-2(3H)-one (3BDO) represents an autophagy inhibitor and activates the mTOR pathway. It has been reported that 3BDO shows anti-cancer activities in lung carcinoma. However, the effects of 3BDO on GBM reminds unknown. Therefore, the purpose of this study was to explore the role and molecular mechanisms that 3BDO mediates in GBM.MethodCCK-8 experiments and clone formation assay were performed to detect the cell proliferation. Transwell assay was conducted to examined cell migration and invasion. Western blotting and immunofluorescence staining was used to analyze protein expression levels. Xenograft mouse model was used to evaluate the effect of 3BDO in vivo.ResultsWe found that 3BDO inhibited U87 and U251 cell proliferation in a dose-dependent manner. Additonally, 3BDO decreased the sphere formation and stemness markers (sox2, nestin and CD133) in GSCs. 3BDO also inhibited migration, invasion and suppressed EMT markers (N-cadherin, vimentin and snail) in GBM cells. Moreover, we found that 3BDO downregulated survivin expression of survivin both in GBM cells (U87, U251) and GSCs. Furthermore, overexpression of survivin reduced the therapeutic effects of 3BDO on GBM cell EMT, invasion, migration and proliferation, as well as decreased stemness in GSCs. Finally, we demonstrated that 3BDO inhibited tumor growth in a tumor xenograft mouse model constructed using U87 cells. Similar to the in vitro findings, 3BDO diminished suvivin expression, stemness and levels of EMT makers in vivo.Conclusionsour results demonstrated that 3BDO repressed GBM via downregulating survivin-mediated stemness and EMT both in vitro and in vivo.
Digitales Lernen während der Covid-19-Pandemie aus Sicht von Studierenden der Erziehungswissenschaften
Authors: Mulders Miriam , Krah Sophia
Published: January 2021

Der vorliegende Beitrag untersucht die Bedingungen von Lehren und Lernen während der Covid-19-Pandemie. Verantwortliche der Hochschullehre und Studierende waren im Sommersemester 2020 gezwungen, auf digitale Formate des Lehrens bzw. Lernens zurückzugreifen. Im Rahmen der vorliegenden Studie wird auf Grundlage einer Fragebogenstudie mit Bachelorstudierenden des Fachs Erziehungswissenschaften zunächst die derzeitige Situation und das Meinungsbild der Studierenden differenziert erfasst und dargestellt. Anschliessend werden Faktoren herausgearbeitet, die aus Studierendenperspektive zentral für den erfolgreichen Einsatz von digitalen Formaten in der Hochschullehre sind. Aufbauend darauf werden Unterstützungsbedarfe identifiziert und Handlungsempfehlungen für die Gestaltung von digitalem Lehren und Lernen formuliert. Die Untersuchungsergebnisse weisen darauf hin, dass das Sommersemester 2020 eine Herausforderung für alle Beteiligten gewesen ist. Besonders technologische Hürden erschwerten das Studieren. Auch didaktische und organisatorische Gestaltungsaspekte digitaler Lehr- und Lernkonzepte bestimmten das Studierverhalten. Die Untersuchung liefert wichtige Hinweise hinsichtlich digital (bzw. digital angereicherter) Lehre. Diese sind wegweisend, um die Lehre in der gegenwärtigen Situation erfolgreich durchzuführen und um die Qualität der Lehre und des Lernens im Hochschulbereich zu sichern.
Remote Assessment in Higher Education during COVID-19 Pandemic
Authors: ŞENEL Selma , ŞENEL Hüseyin Can
Published: January 2021

Universities have made a compulsory shift to distance education due to the Covid-19 pandemic. All of the higher education instutitions in Turkey have completed 2019-2020 Spring semester using online tools. However, most of these institutions were not fully-prepared to have all of their courses online. Technical inadequencies, lack of qualified online tools, inexperience of instructors and students in distance education have emerged as major issues that instutitions have to face. In addition to all, a new question arised; which approaches will be used for assessment. This study aimed to seek the common assessment approaches used through pandemic, how students perceived the quality of the assessment and the pros and cons of using these practices. Additionally, we examined whether participants’ perceptions about quality of the assessment differ according to interaction with faculty members and use of online tests. Researchers employed survey design to reply four research questions and used a three-part instrument to collect qualitative and quantitative data. 486 students from 61 universities voluntarily participated in the study. Results indicated assignments are the mostly used tools and students are generally satisfied about the quality of the assessment practices. Another result is that students who interact with faculty members are more satisfied with the quality of the assessment practices. This emphasizes the importance of formative assessment and feedback in remote assessment. Further, students who took online tests are more satisfied with the quality of assessment. Suggestions were made for future research.
Nutrient uptake analysis of black cohosh (Actaea racemosa L.) grown under shade
in greenhouse
Authors: Robinson Julia , Yang Guochen , Gu Sanjun , Lu Zhongge , Holmes Bryce
Published: January 2021

This research was determining optimal fertilizing strategies for Black cohosh, as an herbal alternative for menopause, to increase crop productivity. Nutrient uptake was analyzed on one-year old plants grown under 80% shade in a greenhouse and exposed to two nutrient application treatments: single and continuous exposures of fertilizer at 0%, 2%, 4%, 6%, 8% and 10% concentrations during a one-year study. Two respective experimental designs were used for growth data and nutrient uptake analysis. Growth data was using a Completely Randomized Split Plot Design, with two treatment groups, single exposure and continuous exposures of fertilizer, and six subplots for each concentration. Nutrient uptake analysis was using a Completely Randomized Design and conducted only on single exposure fertilizer treatment for total amount of calcium, iron, potassium, magnesium, manganese and zinc. Single exposure (5 replications) of fertilizer had one application of fertilizer solution per concentration, to soil, one week before planting, while continuous exposure (7 replications) of fertilizer had an initial application of fertilizer solution one week before planting and subsequent application of fertilizer solution per concentration, once a week for entire growing season. Continuous exposure led to a significant decrease in growth and rhizome weights, and a significant increase in stem number per plant as fertilizer concentration increased. No growth change was observed with a single exposure of fertilizer, except for a decrease in stem length. Black cohosh mainly utilizes calcium, potassium, magnesium and zinc as it fully matured, and manganese since initial growing stage. Calcium and magnesium accumulated primarily in leaves, while potassium accumulated in stem and iron in rhizome