bluuebunny/crossref_metadata_2025 huggingface dataset:
Did the COVID-19 pandemic affect auditors’ client acceptance and continuance decision-making process?
Authors: Papadopoulou Sofia
Published: March 2023

Purpose

The aim of the present study is to explore the impact of the COVID-19 pandemic on the first stage of external audit, namely, on the auditors’ client acceptance and continuance decisions (CACDs).

Design/methodology/approach

Survey data was collected on the basis of a structured questionnaire, which was answered by 21.02% of the Greek certified auditors/accountants. Parametric hypothesis testing and regression analysis were used in data analysis.

Findings

The results of the survey showed that the COVID-19 pandemic had a different impact on the client acceptance decision-making (CAD) process and the client continuance decision-making (CCD) process. The CAD process appears to have been affected in a mostly negative way, and to a greater extent than is the case with the CCD process. The impact of the COVID-19 pandemic on the CACD process appears to be mainly related to the difficulty arising in auditor–client communication. Additionally, as far as the CAD process is concerned, the COVID-19 pandemic appears to have had a negative impact on the audit fees, while, when it comes to the CCD process, the pandemic has had a positive impact with regard to clientele expansion. Finally, survey findings showed that the COVID-19 pandemic affected in a different way Big6 and non-Big6 auditors.

Originality/value

The present study aspires to fill significant gaps identified in relevant literature with regard to auditors’ work in correlation with the COVID-19 pandemic. More specifically, to the best of the author’s knowledge, it is the first study exploring the impact of the COVID-19 pandemic on the first stage of external audit. Moreover, the study is based on primary data collected in real time, under the actual conditions of emergency related to the health crisis. Last but not least, the findings of the present study could be of value to professionals and regulative authorities in case of similar future emergencies or potential crisis situations.
Exploring perceived barriers for advancement to leadership positions in healthcare: a thematic synthesis of women's experiences
Authors: Haines Alexandra Claire , McKeown Eamonn
Published: March 2023

Purpose

This paper aims to explore the voices of women describing the perceived barriers for advancing to leadership positions in healthcare.

Design/methodology/approach

A systematic search was conducted through Elton B Stephans Company (EBSCO) host research platform using the databases Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete, Medical Literature Analysis and Retrieval System Online (MEDLINE) Complete and American Psychological Association (APA) PsycInfo. Nine papers were selected for this review. Thomas and Harden's (2008) method of thematic synthesis was used drawing from eight qualitative papers and one mixed methods paper describing women's lived experiences in, or advancing to, leadership positions in the healthcare sector. Analysis was conducted using three steps of thematic synthesis: the inductive coding of the text, the development of descriptive themes and the generation of analytical themes.

Findings

Through the method of thematic synthesis, six descriptive themes (barriers) emerged: internalised feelings, work–life balance, lack of support, stereotypes, discriminatory behaviours and organisational culture. From these, three analytical themes were identified: personal, interpersonal and organisational.

Research limitations/implications

This review looked at nine papers and documented women's voices. However, the women were in disparate geographical areas across the world and did not consider the specific cultural context in which the women were located. The healthcare sector is very large, and therefore, whilst there are shared commonalities, the disparateness could be a limitation.

Practical implications

Barriers were categorised as either structural barriers or attitudinal barriers to determine the policy and practice.

Originality/value

This research is crucial to better understanding what remedies need to be implemented to address gender disparity in the sector.
The “V” model for decision analysis of additive manufacturing implementation
Authors: De Lima Anderson Ferreira , Satyro Walter Cardoso , Contador José Celso , Fragomeni Marco Aurélio , Gonçalves Rodrigo Franco , Martens Mauro Luiz , Pereira Fabio Henrique
Published: March 2023

Purpose

This study aims to broaden the understanding of the additive manufacturing (AM) body of knowledge, presenting a model better suited to the current level of technological development that supports the decision to implement AM in industries, based on the experience of companies in the industry of orthopedic medical implants.

Design/methodology/approach

Based on the design-science research, the model for the decision to adopt the AM was designed and submitted to experts from the industry of orthopedic implants in Brazil for refinement. For the empirical test of the final model, interviews were used in a company that was considering implementing AM and in another that was not, to evaluate the model.

Findings

The model considers seven dimensions for decision analysis of AM implementation: legal constraints, financial, technological, operational, organizational, supply chain and external factors, being subdivided into 42 criteria that play a relevant role in the implementation decision. The analysis factor of each dimension and criteria are also presented.

Originality/value

The model seeks to be as complete as possible and can be used by various industrial productive sectors, incorporating the analysis of the requirements of health regulatory agencies, suitable for the analysis of the decision to implement AM for the manufacturing of medical implants, not found in other models.
Does integrated store service quality stimulate omnichannel shoppers' augmenting, co-developing, influencing and mobilizing behaviors? Moderating role of perceived relationship investment
Authors: Natarajan Thamaraiselvan , Ramanan V Deepak
Published: March 2023

Purpose

Building on Stimulus Organism Response theory, the current study examines the influence of Integrated store service quality (ISSQ) on the omnichannel customer experience dimensions (Cognitive, Affective and Relational), subsequently leading to their psychological ownership of the store, which eventually explains their Augmenting, Co-developing, Influencing and Mobilizing behaviors. The moderating role of omnichannel shopper perceived relationship investment in a few proposed relationships was tested.

Design/methodology/approach

The research is a descriptive, quantitative and cross-sectional investigation. A purposive sampling technique was used. It was conducted using data collected from 554 Indian omnichannel shoppers using a validated self-administered questionnaire. The proposed conceptual model was tested using PLS-SEM.

Findings

The results indicate that ISSQ positively impacts all three dimensions of omnichannel customer experience (cognitive, affective and relational). All three dimensions directly affect psychological ownership, eventually impacting their (Augmenting, Co-developing, Influencing and Mobilizing) engagement behaviors. The moderating effect of the omnichannel shopper, perceived relationship investment, revealed that it had a significant positive impact on the relationship between dimensions of omnichannel customer experience and psychological ownership of shoppers towards the store, which eventually fosters the customer–retailer value co-creation like engagement behaviors.

Research limitations/implications

The study is conducted in the Indian population, where omnichannel retailing is still nascent.

Originality/value

This study addresses the need to investigate other dimensions (apart from cognitive and affective) of the omnichannel customer experience that might eventually influence various service firms' customer engagement behaviors. This study is the first to show that integrated store service quality might stimulate (Augmenting, Co-developing, Influencing and Mobilizing) engagement behaviors through customer experience dimensions and the customer's sense of belongingness to the store. The moderating role of omnichannel shoppers' perceived relationship investment in a few proposed relationships was tested.
Agential explanations: how employee participation is enhanced in normatively controlled organizations?
Authors: Hassan Danial , Nadeem Sadia
Published: March 2023

Purpose

The study aims to highlight and understand, and bring the human agency into the debate on the theory of normative control. While, the previous literature has highlighted the problem of the missing subject. However, the actual human agency in terms of agential properties has not been seriously addressed. This study is an attempt to overcome this problem of the missing subject.

Design/methodology/approach

A two-phase design inspired by retroductive inference was adopted for this study. In the first phase, abduction was used to explore the literature on normative control to highlight the forces of attraction, which may pull the employees to participate willingly within normative control systems. In the second phase, following retroductive inference, agential explanations of the forces of attraction identified in the first phase were explored by venturing into other related fields, e.g. psychology and sociology.

Findings

The study highlights four strategies used by organizations using normative control, i.e. comfort zoning, relational bonding, moral trapping and elitist appeal. These strategies rely on attractive forces. These forces of attraction pull employees to participate in the normative control system. The attractive element in the identified strategies is due to the fact that these strategies target specific agential properties, i.e. the need for comfort, sense of belonging, moral agency and pride. Overall, the findings suggest that individuals drive their concerns from culture but in relation to their capacity as needy beings for being enculturated.

Practical implications

Theoretically, this study adds conceptual strength to the explanations of normative control. It is suggested that neglect of human agency renders explanations conceptually weak. The study fills this gap in the research. Practically, this study would be beneficial for better design and implementation of normative control. Several studies have pointed out that normative control does not yield the intended results. Out of many reasons, a lack of understanding of human agency is a major cause of unsuccessful attempts to normatively control employees. This study provides some basis to understand the human subject for better design of soft systems of control.

Originality/value

To the best of the authors’ knowledge, this is the first research study that explores agential properties with reference to normative control systems. This study is important for researchers and practitioners.
Selective disassembly sequence optimization based on the improved immune algorithm
Authors: Ji Jiaqi , Wang Yong
Published: March 2023

Purpose

The purpose of this paper is to improve the automation of selective disassembly sequence planning (SDSP) and generate the optimal or near-optimal disassembly sequences.

Design/methodology/approach

The disassembly constraints is automatically extracted from the computer-aided design (CAD) model of products and represented as disassembly constraint matrices for DSP. A new disassembly planning model is built for computing the optimal disassembly sequences. The immune algorithm (IA) is improved for finding the optimal or near-optimal disassembly sequences.

Findings

The workload for recognizing disassembly constraints is avoided for DSP. The disassembly constraints are useful for generating feasible and optimal solutions. The improved IA has the better performance than the genetic algorithm, IA and particle swarm optimization for DSP.

Research limitations/implications

All parts must have rigid bodies, flexible and soft parts are not considered. After the global coordinate system is given, every part is disassembled along one of the six disassembly directions –X, +X, –Y, +Y, –Z and +Z. All connections between the parts can be removed, and all parts can be disassembled.

Originality/value

The disassembly constraints are extracted from CAD model of products, which improves the automation of DSP. The disassembly model is useful for reducing the computation of generating the feasible and optimal disassembly sequences. The improved IA converges to the optimal disassembly sequence quickly.
Impact of global macroeconomic factors on spillovers among Australian sector markets: Fresh findings from a wavelet‐based analysis
Authors: Jiang Zhuhua , El Khoury Rim , Alshater Muneer M. , Yoon Seong‐Min
Published: March 2023

This study investigates the spillover dynamics among 10 Australian sectoral indices and their connectedness to global factors, including the WTI crude oil price, oil market volatility, Australian exchange rate, U.S. stock market volatility index and Infectious Disease Tracker Index. Using data from May 14, 2007 to March 31, 2022, this study applies the time‐varying parameter vector autoregressive model to study their static and dynamic connectedness, wavelet coherence analysis to investigate the time‐frequency co‐movement of global macroeconomic factors with Australian sector stock indices and wavelet decomposition‐based Granger causality. The results show that aggressive stocks (Industrials, Consumer Discretionary and Financials) are net transmitters, while defensive stocks (Health, Information Technology, Communication and Utilities) are net receivers of spillovers. The coronavirus pandemic has increased systemic risk, causing radical changes in net connectedness. Additionally, global macroeconomic factors drive the connectedness of the Australian sectoral indices, with oil and exchange rates moving in phase, and oil volatility, stock volatility and the Infectious Disease Tracker Index moving in antiphase. Global stock and oil market volatility has a significant impact on the Australian sector's returns over short‐, medium‐ and long‐term horizons. This study provides valuable insights to investors and policymakers by carefully examining the relationships between global factors and Australian sectoral indices.
Medicare advantage and dialysis facility choice
Authors: Marr Jeffrey , Akosa Antwi Yaa , Polsky Daniel
Published: March 2023

Objective

To compare the characteristics of dialysis facilities used by traditional Medicare (TM) and Medicare advantage (MA) enrollees with end‐stage kidney disease (ESKD).

Data Sources

We used 20% TM claims and 100% MA encounter data from 2018 and publicly available data from the Centers for Medicare and Medicaid Services.

Study Design

We compared the characteristics of the dialysis facilities treating TM and MA patients in the same ZIP code, adjusting for patient characteristics. The outcome variables were facility ownership, distance to the facility, and several measures of facility quality.

Data Collection/Extraction

We identified point prevalent dialysis patients as of July 15, 2018.

Principal Findings

Compared to TM patients in the same ZIP code, MA patients were 1.84 percentage points more likely to be treated at facilities owned by the largest two dialysis organizations and 1.85 percentage points less likely to be treated at an independently owned facility. MA patients went to further and lower quality facilities than TM patients in the same ZIP code. However, these differences in facility quality were modest. For example, while the mean dialysis facility mortality rate was 21.85, the difference in mortality rates at facilities treating MA and TM patients in the same ZIP code was 0.67 deaths per 100 patient‐years. Similarly, MA patients went to facilities that were, on average, 0.15 miles further than TM patients in the same ZIP code.

Conclusion

MA enrollees with ESKD were more likely than TM enrollees in the same ZIP code to use the dialysis facilities owned by the two largest chains, travel further for care, and receive care at lower quality facilities. While the magnitude of differences in facility distance and quality was modest, the direction of these results underscores the importance of monitoring dialysis network adequacy as ESKD MA enrollment continues to grow.
Climate change and commercial real estate: Evidence from Hurricane Sandy
Authors: Addoum Jawad M. , Eichholtz Piet , Steiner Eva , Yönder Erkan
Published: March 2023

We study how professional investors capitalize flood risk in commercial real estate (CRE) markets after hurricane Sandy. We show that New York CRE exposed to flood risk trades at a large, persistent discount. CRE in Boston, which mostly escaped direct hurricane‐related damage, also exhibits persistent price penalties. These price effects are driven by asset‐level capitalization rates, not building occupancy. Results from a placebo test using real estate prices in Chicago show that our inferences are not driven by coincidental, unrelated price trends for waterfront real estate assets. Our results are consistent with professional investors responding to a persistent shift in the salience of flood risk post‐Sandy, even in locations spared by the disaster.
The relationship between depressed affect, parental monitoring, and sex on cannabis use among American Indian youth
Authors: Haruyama Dorothy , Prince Mark A. , Swaim Randall C. , Chavez Ernest L.
Published: March 2023

Background and Objectives

American Indian (AI) adolescents report higher rates of cannabis use than national US adolescents. Previous study examined interactive relationships between depressed affect and family factors on AI adolescent alcohol use. These factors have not been investigated for cannabis use. We examined whether parental monitoring dampened risk for cannabis use due to depressed affect, and potential moderation by sex.

Methods

We measured cannabis use, depressed affect, parental monitoring, and sex among reservation area AI youth among students in grades 7–12 attending 45 schools. We used censor‐inflated regression models to identify parental monitoring as a moderator of the relationship between depressed affect and cannabis use.

Results

In the logistic portion of censor‐inflated models, level of depressed affect and parental monitoring significantly related to last 30‐day cannabis use. Higher levels of parental monitoring at lower levels of depressed affect related to lower likelihood of cannabis use. Female students had greater likelihood of endorsing cannabis use at higher levels of depressed affect. In the linear portion of the censor‐inflated regression models, sex and level of parental monitoring significantly related to cannabis use frequency. Male students endorsed more frequent cannabis use while higher levels of parental monitoring related to lower frequency of use.

Discussion and Conclusions

Parental monitoring may dampen the effect of depressed affect on cannabis use among AI youth on reservations.

Scientific Significance

Future interventions should foster skill‐building prevention efforts directed at coping with depression, along with parental training for effective monitoring. Special attention to AI female adolescents may be indicated.
Opioid use disorder at delivery hospitalization in the United States: 2012–2016
Authors: Malhotra Tani , Sheyn David , Arora Kavita S.
Published: March 2023

Background and Objectives

The objective of this paper is to evaluate national trends, socioeconomic risk factors, and maternal and obstetric outcomes for patients with and without opioid use disorder (OUD) at delivery hospitalization.

Methods

This is a retrospective cohort using the National Inpatient Sample 2012–2016 of 3,554,477 deliveries to analyze trends in OUD in patients at delivery hospitalization. We conducted univariable and multivariable logistic regression to compare clinical, demographic, hospital, and geographic associations for patients with OUD during delivery hospitalization.

Results

The incidence of OUD at delivery hospitalization increased from 4.48 per 1000 deliveries in 2012 to 7.67 in 2016. The highest rate of OUD was in the Northeast and the lowest in the West (9.29 vs. 4.13 per 1000, respectively, p < .001). After adjusting for confounders, history of concurrent cocaine use (adjusted odds ratio [aOR] = 5.95, 95% confidence interval [CI]: 5.38–6.59), sedative use (aOR = 17.28, 95% CI: 14.71–20.31), and amphetamine use (aOR = 4.05, 95% CI: 3.71–4.43), were strongly associated with OUD. Additionally, hepatitis C infection, (aOR = 21.98, 95% CI: 20.89–23.11), white race (aOR = 3.12, 95% CI: 3.00–3.24), and public insurance (aOR = 3.92, 95% CI: 3.77–4.08) were also associated with OUD.

Discussion and Conclusion

The continued increase in rates of OUD at delivery hospitalization and its association with adverse perinatal outcomes highlights the need for universal screening and resource allocation for programs directed toward pregnant people.

Scientific Significance

Our study builds upon the prior literature that reports trends in OUD at delivery hospitalization from 1998 to 2011 as well as presents a more in‐depth look at risk factors and adverse pregnancy outcomes than previously reported.
Is exposure to pollen a risk factor for moderate and severe asthma exacerbations?
Authors: Annesi‐Maesano Isabella , Cecchi Lorenzo , Biagioni Benedetta , Chung Kian Fan , Clot Bernard , Collaud Coen Martine , D'Amato Gennaro , Damialis Athanasios , Dominguez‐Ortega Javier , Galàn Carmen , Gilles Stefanie , Holgate Stephen , Jeebhay Mohamed , Kazadzis Stelios , Papadopoulos Nikolaos G. , Quirce Santiago , Sastre Joaquin , Tummon Fiona , Traidl‐Hoffmann Claudia , Walusiak‐Skorupa Jolanta , Alonso‐Coello Pablo , Canelo‐Aybar Carlos , Cantero‐Fortiz Yahveth , Rigau David , Salazar Josefina , Verdugo‐Paiva Francisca , Jutel Marek , Akdis Cezmi A. , Agache Ioana
Published: March 2023

Limited number of studies have focused on the impact of pollen exposure on asthma. As a part of the EAACI Guidelines on Environment Science, this first systematic review on the relationship of pollen exposure to asthma exacerbations aimed to bridge this knowledge gap in view of implementing recommendations of prevention. We searched electronic iPubMed, Embase, and Web of Science databases using a set of MeSH terms and related synonyms and identified 73 eligible studies that were included for systemic review. When possible, meta‐analyses were conducted. Overall meta‐analysis suggests that outdoor pollen exposure may have an effect on asthma exacerbation, but caution is needed due to the low number of studies and their heterogeneity. The strongest associations were found between asthma attacks, asthma‐related ED admissions or hospitalizations, and an increase in grass pollen concentration in the previous 2‐day overall in children aged less than 18 years of age. Tree pollen may increase asthma‐related ED visits or admissions lagged up to 7‐day overall in individuals younger than 18 years. Rare data show that among subjects under 18 years of age, an exposure to grass pollen lagged up to 3 days may lower lung function. Further research considering effect modifiers of pollen sensitization, hay fever, asthma, air pollution, green spaces, and pre‐existing medications is urgently warranted to better evaluate the impacts of pollen on asthma exacerbation. Preventive measures in relation to pollen exposure should be integrated in asthma control as pollen increase continues due to climate change.
Evaluating antenatal risk in twin pregnancies—A feasibility study to identify modifiable factors associated with adverse pregnancy outcomes
Authors: Greatholder Isabelle , Tomlinson Emma , Wilkinson Jack , Higgins Lucy E. , Kilby Mark D. , Heazell Alexander E. P.
Published: March 2023

Introduction

Twin pregnancies have significantly higher rates of perinatal morbidity and mortality compared to singleton pregnancies; current attempts to reduce perinatal mortality have been less successful in twin pregnancies. The paucity of information about modifiable risk factors for adverse neonatal outcomes in twin pregnancies, as well as independent effects of chorionicity may have contributed to this outcome. This study aimed to explore the feasibility of an observational study to identify modifiable factors associated with adverse neonatal outcomes in twin pregnancies.

Material and methods

Patients pregnant with twins at six UK hospitals between December 2019–March 2021 completed researcher‐administered questionnaires at approximately 20‐, 28‐ and 36‐weeks' gestation, recording a wide range of self‐reported social, lifestyle and demographic factors, alongside prospectively recorded clinical data from maternity records. Descriptive statistics were used to describe frequencies of exposures; logistic regression was used to determine whether factors were associated with a composite measure of adverse neonatal outcome.

Results

Data were collected from 65% (181/277) of eligible participants. A total of 98% (175) of participants had positive views about their participation. Some exposures, including cigarette smoking, supine sleep position and reduced fetal movements were less frequent in twin pregnancies compared to singletons, whereas fertility treatment was more common. Furthermore, different patterns of exposure were seen between monochorionic and dichorionic twins. This pilot study found some associations with adverse neonatal outcomes including: low BMI (OR 8.36, 95% CI: 1.02–68.87), maternal age ≥41 years (OR 9.0 95% CI: 1.07–75.84), maternally perceived high‐stress levels (OR 1.96, 95% CI: 1.03–3.75) and inadequate antenatal screening (OR 1.44, 95% CI: 1.01–2.06). Sleep duration ≥9 h and right‐sided going to sleep position were more frequent among pregnancies with adverse outcomes. Participants who reported receiving no information on fetal movement and reduced maternal perception of movements were more likely to have an adverse outcome, but sample size prohibited analysis based upon chorionicity.

Conclusions

An observational study of modifiable factors in twin pregnancy is feasible. Differences in the frequencies of exposures between twin and singleton pregnancies highlight the need for twin‐specific studies to identify modifiable factors and develop preventative strategies for morbidity and mortality in twin pregnancies.
SARS‐CoV‐2 placentitis and severe pregnancy outcome after maternal infection: A Danish case series
Authors: Nielsen Stine Y. , Hvidman Lone E. , Aabakke Anna J. M. , Olsen Tina E. , Johnsen Iben B. G. , Bogaard Pauline W. , Petersen Astrid , Westergaard Hanne B. , Sørensen Anne , Hedermann Gitte , Rønneberg Elisabeth T. , Thisted Dorthe , Boris Jane , Andersen Lise L. T. , Eggers Anne G. H. , Lindved Birgitte F. , Henriksen Tine B.
Published: March 2023

Introduction

SARS‐CoV‐2 infection during pregnancy may cause viral inflammation of the placenta, resulting in fetal demise even without fetal or newborn infection. The impact of timing of the infection and the mechanisms that cause fetal morbidity and mortality are not well understood.

Material and methods

To describe placental pathology from women with confirmed SARS‐CoV‐2 infection during pregnancy, a SARS‐CoV‐2 immunohistochemistry‐positive placenta and late miscarriage, stillbirth, neonatal death, or medically indicated birth due to fetal distress.

Results

The triad of trophoblastic necrosis, inflammatory intervillous infiltrates, and increased perivillous fibrinoid deposition was present in all 17 placentas; the pregnancies resulted in eight stillbirths, two late miscarriages (19 and 21 weeks’ gestation), and seven liveborn children, two of which died shortly after delivery. The severity of maternal COVID‐19 was not reflected by the extent of the placental lesions. In only one case, SARS‐CoV‐2 was detected in lung tissue samples from the fetus. The majority events (miscarriage, stillbirth, fetal distress resulting in indicated birth, or livebirth, but neonatal death) happened shortly after maternal SARS‐CoV‐2 infection was diagnosed. Seven of eight sequenced cases were infected with the Delta (B.1.617.2) virus strain.

Conclusion

We consolidate findings from previous case series describing extensive SARS‐CoV‐2 placentitis and placental insufficiency leading to fetal hypoxia. We found sparse evidence to support the notion that SARS‐CoV‐2 virus had infected the fetus or newborn.
Risk of obstetric and perinatal complications in women presenting with breast cancer during pregnancy and the first year postpartum in Sweden 1973–2017: A population‐based matched study
Authors: Lundberg Frida E. , Gkekos Leo , Rodriguez‐Wallberg Kenny A. , Fredriksson Irma , Johansson Anna L. V.
Published: March 2023

Introduction

For women presenting with breast cancer during pregnancy, treatment guidelines were historically restricted to only surgical treatment. Over the past decades, chemotherapy administered during pregnancy has been gradually introduced. Although breast cancer treatments during ongoing pregnancy have been deemed safe, detailed information on potential obstetric risks is lacking. We aimed to assess the risk of adverse obstetric and perinatal outcomes of breast cancer in pregnancy and within 1 year postpartum and in relation to trimester at breast cancer diagnosis, tumor stage, and cancer treatment during pregnancy.

Material and methods

Population‐based matched study. Women diagnosed with breast cancer during pregnancy in 1973–2017 were identified in the Swedish Cancer Register and the Medical Birth Register, with additional information from the National Quality Register for Breast Cancer. Each birth with maternal breast cancer (n = 208 pregnant, n = 672 postpartum) was matched by age, calendar year, and birth order to 10 unexposed births from cancer‐free women in the population (n = 2080 and n = 6720). Adjusted conditional logistic and multinomial regression models were used to estimate odds ratios and relative risk ratios, commonly denoted relative risks (RR) with 95% confidence intervals (CI), of adverse obstetric and perinatal outcomes.

Results

Breast cancer during pregnancy was associated with higher risks of preterm birth, both planned (RR 67.1, 95% CI 33.2–135.6) and spontaneous preterm birth (RR 3.8, 95% CI 2.0–7.5), and low birthweight (<2500 g: RR 7.5, 95% CI 4.9–11.3). The associated risks were higher if the breast cancer was diagnosed in the second trimester, and of similar magnitude irrespective of stage and treatment groups. There was a higher risk of low birthweight for gestational age (<25th centile) if breast cancer was diagnosed in the first trimester (RR 2.8, 95% CI 1.1–7.3). Risks of other pregnancy complications were similar to those of unexposed women, as were risks of neonatal mortality and malformations. Postpartum breast cancer was only associated with bleeding during pregnancy (RR 1.6, 95% CI 1.0–2.8).

Conclusions

Preterm birth and related adverse outcomes were more common in women diagnosed with breast cancer during pregnancy. Reassuringly, breast cancer was not associated with other maternal pregnancy complications or adverse outcomes in children.
Postural balance under sensory manipulation predicted fine and gross motor skills in children from 5 to 6 years of age
Authors: Mnejja Khouloud , García‐Soidan Jose Luis , Romo‐Perez Vicente , Sahli Sonia
Published: March 2023

Aim

Our aim was to identify predictors of fine and gross motor skills at 5–6 years of age using postural balance under sensory manipulation.

Methods

This study was conducted during the 2021–2022 academic year and focused on 112 children from three preschools in Tunisia, with roughly the same socio‐economic status. Postural balance was assessed with their eyes open and closed on both firm and foam surfaces and motor skills were measured using the short version of Bruininks–Oseretsky Test of Motor Proficiency, Second Edition (Bot‐2). Multiple linear regression analysis with stepwise backward selection was used to find a simplified model that best explained the data.

Results

Postural balance accounted for 11% of the total variation in fine motor skills, except for the eyes open firm condition, 10% of the gross motor skills and about 14% of the total Bot‐2 score. The eyes open foam condition was the only significant contributor to the gross motor skills model and the overall motor score.

Conclusion

Assessing postural balance assessment at 5–6 years of age may predict motor skills. It may be useful for monitoring early child development and designing physical activity programmes for this age group.
Editorial: deja vu all over again—let the P‐CAB wars begin
Authors: Metz David C.
Published: March 2023

LINKED CONTENT

This article is linked to Hwang et al papers. To view these articles, visit https://doi.org/10.1111/apt.17406 and https://doi.org/10.1111/apt.17444
Letter: be careful of gastrointestinal CMV infection in adverse events from ICIs therapy in solid tumours
Authors: Parente Paola , Ascani Stefano , Maiorano Brigida Anna , Zanelli Magda , Ciardiello Davide
Published: March 2023

LINKED CONTENT

This article is linked to Dahl et al papers. To view these articles, visit https://doi.org/10.1111/apt.17201 and https://doi.org/10.1111/apt.17431
Letter: dietitians are more than coaches
Authors: Gibson Peter R.
Published: March 2023

LINKED CONTENT

This article is linked to Wang et al papers. To view this article, visit https://doi.org/10.1111/apt.17221
Infrastructure and politics: Why the Belt and Road Initiative proceeded differently in Malaysia and Indonesia
Authors: Wang Zhaohui
Published: March 2023

The article seeks to understand the different types and sources of politicisation as well as the consequences for Belt and Road Initiative infrastructure projects. It is argued that while the personalised insulated type of foreign policymaking is conducive to intra‐system politicisation, the institutionalised responsive type is associated with extra‐system politicisation. While the former type is contingent on political turnovers and brings about abrupt shocks, the latter oftentimes generates societal pushback from socio‐economic groups. The article focuses on two flagship Belt and Road Initiative infrastructure projects in Malaysia and Indonesia. Based on fieldwork interviews and process tracing, the article finds that the East Coast Rail Link project in Malaysia has suffered from high risk of political interruption owing to Malaysia's personalised insulated type of foreign policymaking, whereas the Jakarta–Bandung High Speed Rail project in Indonesia has encountered sustained obstacles from Indonesian society and brought about substantial delays under Indonesia's institutionalised responsive type.
Childhood trauma and cognitive functioning in mood disorders: A systematic review
Authors: Barczyk Zoe A. , Foulds James A. , Porter Richard J. , Douglas Katie M.
Published: March 2023

Background

Cognitive impairment is a core feature of mood disorders and has been identified as an important treatment target. A better understanding of the factors contributing to cognitive impairment in mood disorders would be beneficial in developing interventions to address cognitive impairment. One key factor is childhood trauma. The aim of this review was to systematically synthesise and review research examining associations between reported childhood trauma and cognitive functioning in mood disorders.

Methods

Studies in adult samples examining the relationship between objective cognitive function and reported childhood trauma in major depressive disorder and/or bipolar disorder (in‐episode or euthymia) were identified. Searches were conducted on PubMed, Embase and PsycINFO until January 2022. A narrative review technique was used due to the heterogeneity of group comparisons, cognitive tests and data analysis across studies.

Results

Seventeen studies met the criteria for inclusion (mood disorders N = 1723, healthy controls N = 797). Evidence for childhood trauma being related to poorer cognitive functioning was consistent across global cognitive functioning and executive function domains for euthymic patients and psychomotor speed for in‐episode patients. There was mixed evidence for verbal learning and memory and executive function for in‐episode patients. Identification of patterns within other domains was difficult due to limited number of studies.

Conclusion

Findings from this review suggest childhood trauma is associated with poorer cognitive functioning in people with mood disorders. Targeted interventions to improve cognition may be warranted for this group.
Does performance persistence below aspirations affect firms' accounting information disclosure strategies? An empirical study based on reliability and comparability
Authors: Zhong Xi , Ren Liuyang , Ren Ge
Published: March 2023

Integrating the behavioral theory of the firm and agency theory, this study is the first to examine the antecedents of firms' choice to disclose low‐quality accounting information from the perspective of performance persistence below aspirations. Based on empirical data of 31,326 firm‐annual observations involving 3584 listed companies for the 2007–2021 period, we find that firms actively reduce accounting information reliability and comparability in the presence of performance persistence below aspirations. Furthermore, we find that CEO‐CFO surname ties enhance the negative effect of performance persistence below aspirations on accounting information comparability. Finally, we find that agency costs play a mediating role in the relationship that performance persistence below aspirations has with accounting information reliability and comparability. This study is the first to examine performance persistence below aspirations and accounting information reliability and comparability. Meanwhile, this study provides important insights for policymakers to improve the quality of capital market information and for shareholders to improve the quality of corporate governance.
Leveraging new business innovation for strategic renewal: An organizational framework for strategic corporate venturing
Authors: Weiss Lysander , Kanbach Dominik K.
Published: March 2023

To adapt their competitive advantages for successful strategic renewal, established companies must apply suitable innovation activities. One way to achieve this is the establishment of corporate venturing units that create organizationally consequential new business innovation for their parent company. However, the understanding of the distinctive organizational characteristics for such strategic corporate venturing is limited. To address this gap, our abductive study develops a conceptual organizational framework by linking key concepts of strategic renewal with corporate venturing. This framework is subsequently compared with insights emerging from the qualitative data of 29 corporate venturing units. This comparison allows us to define six types of units with different possible roles for the strategic renewal of the parent company, and a final exploratory organizational framework with distinctive organizational characteristics for strategic corporate venturing. These include a set of dynamic capabilities with corresponding resources as possible enablers for a planned innovation logic that requires interlinked‐ambidextrous structures. These findings provide a foundation for an empirical model of strategic corporate venturing, as well as novel insights for establishing dynamic capabilities and ambidexterity within interlinked organizational entities. Practitioners can build on these findings to leverage corporate venturing units as a systematic and organized innovation activity for strategic renewal.
Clinical heterogeneity of NADSYN1‐associated VCRL syndrome
Authors: Aubert‐Mucca Marion , Janel Caroline , Porquet‐Bordes Valérie , Patat Olivier , Touraine Renaud , Edouard Thomas , Michot Caroline , Tessier Aude , Cormier‐Daire Valérie , Attie‐Bitach Tania , Baujat Geneviève
Published: March 2023

The NADSYN1 gene [MIM*608285] encodes the NAD synthetase 1 enzyme involved in the final step of NAD biosynthesis, crucial for cell metabolism and organ embryogenesis. Perturbating the role of NAD biosynthesis results in the association of vertebral, cardiac, renal, and limb anomalies (VCRL). This condition was initially characterized as severe with perinatal lethality or developmental delay and complex malformations in alive cases. Sixteen NADSYN1‐associated patients have been published so far. This study illustrates the wide phenotypic variability in NADSYN1‐associated NAD deficiency disorder. We report the clinical and molecular findings in three novel cases, two of them being siblings with the same homozygous variant and presenting with either a very severe prenatal lethal or a mild phenotypic form. In addition to an exhaustive literature, we validate the expansion of the spectrum of NAD deficiency disorder. Our findings indicate that NAD deficiency disorder should be suspected not only in the presence of the full spectrum of VCRL, but even a single of the aforementioned organs is affected. Decreased plasmatic levels of NAD should then strongly encourage the screening for any of the genes responsible for a NAD deficiency disorder.
Children's ages of consent to non‐urgent heart surgery: The views of two paediatric cardiology teams
Authors: Alderson Priscilla , Bellsham‐Revell Hannah , King Liz , Vigneswaran Trisha , Wray Jo
Published: March 2023

Paediatric cardiology practitioners and related experts report unusually young ages when they begin to inform children about their non‐urgent heart surgery and begin to respect children's consent or refusal. Research methods included observations in two paediatric cardiology units, audio‐recorded interviews with 45 experts, and qualitative data analysis. Significantly younger ages were cited than are usually recommended in the clinical and legal literature. Interviewed practitioners took seriously children's consent to or refusal of a heart transplant from around 6 years, and a child's firm refusal of induction of anaesthesia from around 4 years, when surgery might be postponed.
Formal Models at the Core
Authors: Chemla Emmanuel , Charnavel Isabelle , Dautriche Isabelle , Embick David , Lerdahl Fred , Patel‐Grosz Pritty , Poeppel David , Schlenker Philippe
Published: March 2023

The grammatical paradigm used to be a model for entire areas of cognitive science. Its primary tenet was that theories are axiomatic‐like systems. A secondary tenet was that their predictions should be tested quickly and in great detail with introspective judgments. While the grammatical paradigm now often seems passé, we argue that in fact it continues to be as efficient as ever. Formal models are essential because they are explicit, highly predictive, and typically modular. They make numerous critical predictions, which must be tested efficiently; introspective judgments do just this. We further argue that the grammatical paradigm continues to be fruitful. Within linguistics, implicature theory is a recent example, with a combination of formal explicitness, modularity, and interaction with experimental work. Beyond traditional linguistics, the grammatical paradigm has proven fruitful in the study of gestures and emojis; literature (“Free Indirect Discourse”); picture semantics and comics; music and dance cognition; and even reasoning and concepts. We argue, however, that the grammatical paradigm must be adapted to contemporary cognitive science. Computational methods are essential to derive quantitative predictions from formal models (Bayesian pragmatics is an example). And data collection techniques offer an ever richer continuum of options, from introspective judgments to large‐scale experiments, which makes it possible to optimize the cost/benefit ratio of the empirical methods that are chosen to test theories.
Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti‐tumour properties
Authors: Alessio Nicola , Acar Mustafa Burak , Squillaro Tiziana , Aprile Domenico , Ayaz‐Güner Şerife , Di Bernardo Giovanni , Peluso Gianfranco , Özcan Servet , Galderisi Umberto
Published: March 2023

Genotoxic injuries converge on senescence‐executive program that promotes production of a senescence‐specific secretome (SASP). The study of SASP is particularly intriguing, since through it a senescence process, triggered in a few cells, can spread to many other cells and produce either beneficial or negative consequences for health. We analysed the SASP of quiescent mesenchymal stromal cells (MSCs) following stress induced premature senescence (SIPS) by ionizing radiation exposure. We performed a proteome analysis of SASP content obtained from early and late senescent cells. The bioinformatics studies evidenced that early and late SASPs, besides some common ontologies and signalling pathways, contain specific factors. In spite of these differences, we evidenced that SASPs can block in vitro proliferation of cancer cells and promote senescence/apoptosis. It is possible to imagine that SASP always contains core components that have an anti‐tumour activity, the progression from early to late senescence enriches the SASP of factors that may promote SASP tumorigenic activity only by interacting and instructing cells of the immune system. Our results on Caco‐2 cancer cells incubated with late SASP in presence of peripheral white blood cells strongly support this hypothesis. We evidenced that quiescent MSCs following SIPS produced SASP that, while progressively changed its composition, preserved the capacity to block cancer growth by inducing senescence and/or apoptosis only in an autonomous manner.
Facing the Future: The Legacies of Post‐Neoliberalism in Latin America
Authors: Grugel Jean , Riggirozzi Pia
Published: March 2023

This virtual issue reviews the post‐neoliberalism literature published in Development and Change between 2012 and 2018. It reflects on recent and ongoing, multiple experiences of resistance to speculative, extractive, inequitable and unsustainable development and the demands for alternatives that emerged in Latin America. The argument is developed through an analysis of the 18 most relevant articles published in this journal, that make a major contribution to three key interrelated debates, namely: the meaning and policies associated with post‐neoliberalism; challenges of citizenship and democracy; and the sustainability agenda. Collectively, the selected articles provide a detailed and much‐needed discussion about the key achievements, limitations and legacies of post‐neoliberalism.