bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Buku Petunjuk Praktikum Biologi Umum untuk Mahasiswa Program Sarjana Prodi Tadris Biologi UIN Sayyid Ali Rahmatullah Tulungagung
Authors: Fauziah Arbaul , Fahrudin Ahmad
Published: August 2022

Praktikum merupakan bagian penting dalam proses pembelajaran, khususnya dalam perkuliahan Biologi. Praktikum yang baik perlu dilengkapi dengan komponen penunjang, salah satunya adalah buku petunjuk praktikum. Penelitian ini bertujuan untuk mendeskripsikan substansi, kelayakan, dan respon penggunaan buku petunjuk praktikum Biologi Umum Program Studi Tadris Biologi UIN Sayyid Ali Rahmatullah Tulungagung. Jenis penelitian ini adalah R D dengan model pengembangan ADDIE. Hasil penelitian menunjukkan bahwa substansi buku petunjuk praktikum Biologi Umum prodi Tadris Biologi UIN Sayyid Ali Rahmatullah Tulungagung terdiri dari tata tertib, jadwal praktikum, topik, tujuan, dasar teori, alat dan bahan, cara kerja, dan format lembar pengamatan sementara (LPS). Dilihat dari segi teoritis, desain, akurasi, dan relevansinya dengan materi perkuliahan, buku petunjuk praktikum Biologi Umum dinyatakan layak sebagai penunjang praktikum dengan kriteria sangat valid berdasarkan penilaian oleh ahli materi dan media. Penggunaan buku petunjuk praktikum ini mendapatkan respon positif dengan persentase penilaian yang tinggi. Respon positif ditunjukkan dengan pendapat responden yang menyatakan bahwa buku petunjuk praktikum mudah diperoleh, mudah dipahami, tersaji dengan lengkap, langkah-langkah praktikum dipaparkan dengan jelas sehingga dapat membantu dalam pelaksanaan praktikum.  Practicum is an important part of the learning process, especially in Biology lectures. A good practicum needs to be equipped with supporting components, one of which is a practical handbook. The aims of this study were to describe the substance, feasibility, and response to the use of the General Biology practical handbook for the Tadris Biology Study Program in UIN Sayyid Ali Rahmatullah Tulungagung. The type of research was R D with the ADDIE development model. The results showed that the substance of the General Biology practical handbook for the Tadris Biology Study Program in UIN Sayyid Ali Rahmatullah Tulungagung consisted of rules, practicum schedules, topics, objectives, theoretical basis, tools and materials, working methods, and temporary observation sheet (LPS) format. In terms of theoretical, design, accuracy, and relevance to lecture material, the General Biology practical handbook was declared feasible as a practicum supporter with very valid criteria based on assessments by material and media experts. The use of this practical handbook received a positive response with a high percentage of assessment. The positive response was indicated by the opinion of the respondents who stated that the practical handbook were easy to obtain, easy to understand, fully presented, the practicum steps were explained clearly so that it could assist in practicum implementation.
Analisis Pola Perilaku Buaya Muara (Crocodylus porosus) Di Taman Buaya Indonesia Jaya Bekasi
Authors: Pratiwi Rina Hidayati , Ramadhanty Yosy Ezha , Asih Dwi Aprillia Setia
Published: August 2022

Tiap perilaku buaya dipengaruhi oleh faktor kenyamanan habitat yang merupakan tempat buaya berinteraksi dengan lingkunnganya. Tujuan penelitian adalah untuk menganalisis pola perilaku buaya muara (Crocodylus porosus) yang terdapat di Taman Buaya Indonesia Jaya Bekasi. Metode penelitian yang digunakan untuk menganalisis pola perilaku adalah metode kualitatif dengan teknik pengumpulan data berupa observasi, wawancara dan dokumentasi. Berdasarkan hasilobservasi dan wawancara dapat disimpulkan bahwa persentase frekuensi yang terjadi selama penelitian dari keempat individu buaya muara adalah pola perilaku bergerak (30,94%), pola perilaku berjemur/istirahat (28,68%), pola perilaku sosial (24,59%), pola perilaku makan (15,77%) dan pola perilaku terendah adalah pola perilaku kawin (0%). Crocodile’s behavior was influenced by the convenience factor of the habitat where the crocodile interacts with it environment. The purpose of this study was analyze the behavior patterns of the estuarine crocodile (Crocodylus porosus) found in the Indonesian Crocodile Park Jaya Bekasi. The research method used to analyze behavioral patterns is a qualitative method with data collection techniques in the form of observation, interviews and documentation. Based on the results of observations and interviews, it can be concluded that the percentage of frequencies that occurred during the study of four estuarine crocodiles was movement behavior pattern (30.94%), pattern of sunbathing/resting behavior (28.68%), patterns of social behavior (24.59%), eating behavior pattern (15.77%) and the lowest behavior pattern is mating behavior pattern (0%).
Inventarisasi Tumbuhan Obat Di Desa Golo Ketak Kecamatan Boleng Kabupaten Manggarai Barat, NTT
Authors: Hastuti Hastuti , Herlina Herlina , Amis Rofina Susanti
Published: August 2022

Indonesia is a country with enormous natural wealth, including a wealth of plant species and a diversity of tribes that have local wisdom in the form of traditional medicine traditions. This study aims to: (1) determine the types of medicinal plants; (2) Knowing the plant organs used for treatment; (3) Knowing the process of processing medicinal plants and how to use the ingredients. The research method used is descriptive method and data collection techniques are carried out through observation, interviews, exploration, collection and documentation. The research data were analyzed descriptively and tabulated in tabular form. The results showed: (1) there were 13 species of medicinal plants in Golo Ketak Village, Boleng District, West Manggarai Regency, (2) parts of the plant organs used to treat the roots/rhizomes/tubers, stems, leaves and fruits; (3) the me thod of processing medicinal plants is by boiling, grating, pounding and smearing Indonesia is a country with enormous natural wealth. This includes the richness of plant species and tribes. Every tribe in Indonesia has local wisdom in the form of traditional medicine. This research is an inventory study of medicinal plants conducted in Gelo Ketak Village, Boleng District, West Manggarai Regency, NTT. This study aims to: (1) determine the types of medicinal plants; (2) Knowing the plant organs used for treatment; (3) Knowing the process of processing medicinal plants and how to use the ingredients. The method used is a descriptive method. Data collection techniques were carried using observation, interviews, exploration, collection and documentation. The research data were analyzed descriptively and made in tabular form. The results showed: (1) there were 13 species of medicinal plants in Golo Ketak Village, Boleng District, West Manggarai Regency, (2) parts of the plant organs used to treat the roots/rhizomes/tubers, stems, leaves and fruits; (3) the method of processing medicinal plants is by boiling, grating, pounding and smearing.
Issues of application of administrative supervision of legal entities
Authors: Ershova Kseniya Andreevna
Published: August 2022

The article examines certain issues of criminal liability of legal entities and unresolved issues of countering crimes committed both before the facts of illegal activity are revealed and after the subject to criminal responsibility declared guilty. The effectiveness of countering environmental and economic crime depends on solving the problem of preventing repeated crimes. The object of the study of this article are the norms of administrative and criminal legislation that establish the concept and signs of multiple crimes, as well as administrative supervision of persons convicted of committing a crime and responsibility for evading administrative supervision. The work examines the norms of criminal and administrative law. The analysis of situations requiring resolution at the legislative level is carried out. The ways of improving the current criminal and administrative legislation are proposed. To prepare the article, both general scientific research methods, including analysis, systematization and extrapolation, and special methods of cognition were used. The novelty of the research lies in the construction of concrete proposals for the development of the institution of criminal liability of legal entities and the prevention of their recidivism. The paper emphasizes the need for the execution of court decisions and suggests ways to achieve it. The measures aimed at improving the corporate policy of a legal entity are described. The paper substantiates the need to apply administrative supervision measures to legal entities as a way to protect violated rights.
MANAJEMEN RISIKO PEMBIBITAN KOPI ARABIKA LS 795 (Studi Kasus Kebun Dinas Sukajadi, Kecamatan Wado, Kabupaten Sumedang)
Authors: Pramesti Kreshtanti Ericha , Pardian Pandi
Published: August 2022

Sukajadi official garden is the only one of the government institutions in west java that produces LS 795 arabica coffee seeds and placed at Sumedang regency. In the process of coffee seed production, that various risks affect the optimization of production results. The seedling period is the most important part of coffee growth because good quality seeds will produce coffee cherries with good quantity and quality as well. This research aims to identify the risks that occur and identify risk management strategies in the LS 795 Arabica coffee nursery activity at the Sukajadi Official Garden. Data analysis in this research used a qualitative descriptive method with case study research techniques. The analytical tool used in this research is the House of Risk (HOR) stages 1 and 2. The results show that there are seven stages of LS 795 arabica coffee production, 26 risk events were identified and 25 risk sources, of which 10 risk sources were prioritized to be addressed first, and selected 7 of the 12 most appropriate mitigation actions to address priority risks.
ANALISIS TINGKAT KEPUASAN KONSUMEN TERHADAP KUALITAS PRODUK DAN KUALITAS PELAYANAN RESTORAN CEPAT SAJI McDONALD’S
Authors: Yudha Eka Purna , Rifai Afif Ahmad , Adela Aqila Shafa
Published: August 2022

The quality of a product and service to consumers is a major concern in the trade and service industry. One of the efforts that can be done in increasing the competitiveness of the company is to increase customer satisfaction. The purpose of this study is to 1) determine consumer interest in the products and services provided by McDonald's, 2) analyze the performance of McDonald's in providing satisfaction to its customers, 3) analyze the level of customer satisfaction regarding the products and services provided. The data collection carried out in this study was carried out by distributing 50 questionnaires to McDonald's consumers. Importance Performance Analysis method is used to analyze the effect of product quality and service quality on customer satisfaction. The Customer Satisfaction Index method is used to measure the overall level of customer satisfaction. The results of this study indicate that consumers.
Viral etiology associated with Guillain-Barré Syndrome: seeking an answer to the idiopathic
Authors: Vega-Fernández Jorge A. , Suclupe-Campos Danny O. , Coico-Vega Mayra M. , Aguilar-Gamboa Franklin R.
Published: August 2022

Guillain-Barré Syndrome (GBS) is a rare disorder of the nervous system, where the patient's immune system attacks the peripheral nerve cells in the arms and legs, causing muscle weakness, loss of sensation and sometimes total paralysis. The origin of this disorder has been associated with immune responses triggered by post-infection with Campylobacter spp. However, when there is no obvious cause of the disease, it is usually not investigated due to the greater interest in the treatment. Therefore, most cases are reported as idiopathic origin. Between January and March 2016 worldwide, GBS outbreaks were reported in 8 countries, linked to the emergence of the Zika virus. In Peru, since the end of 2018, outbreaks of GBS have been reported more frequently and although no association with Zika has been confirmed, the increase in cases, the geographical extension where they occurred and the clinical characteristics of affected patients, have common patterns that lead to suspect an infectious origin mainly of viral type. Therefore, it is important to know the current scientific evidence about the role that some viruses play in this syndrome, allowing us to expand our epidemiological picture with new tools to address this disease
Mucinous adenocarcinoma of the cecal appendix
Authors: Contreras Gala Katherine L. , Villafuerte Rozas Mónica
Published: August 2022

Cecal appendix adenocarcinoma occurs in approximately 0.1% to 0.2% of all appendectomies. One subtype, mucinous adenocarcinoma, represents 0.08% of all neoplasms. Diagnosis is usually incidental and surgery is the best treatment option. We describe the case of a 55-year-old male patient, evaluated for severe pain in the right iliac fossa, who was found to have an appendiceal mass during open appendectomy. A fragmented appendix measuring 7 x 1.8 x 0.8cm, with mucoid content in its lumen; as well as mucin pools in more than 50% of the sample and signet ring cells in light microscopy, revealed the pathological diagnosis of mucinous adenocarcinoma. Therefore, the pathological analysis of surgical pieces is transcendental, since there are infrequent diagnoses that can change the prognosis and course of clinical management of a patient.
Health profile of the population that attended to an integral health campaign in the time of COVID-19, at Subtanjalla, Ica 2021
Authors: Huaraca-De los Santos Edgar M. , Guillen-Ponce Norka R. , Morales-Moisela Marlon , Correa-López Lucy E.
Published: August 2022

Objectives: To determine the Health Profile of the population that attended to an integral health campaign in time of COVID-19. Materials and methods: It was an observational, descriptive and retrospective study. A non-probability sampling was carry out. Two hundred and eighty nine medical histories that accomplish the inclusion and exclusion criteria were included. Results: A 64.7% of patients were women and 35.3% were men. Moreover, the most predominant patients who referred COVID-19 were women (8.3%). The majority of patients who referred COVID-19 where among the ages of 15-59 years old (37%). The frequency of comorbidities were obesity (26.6%), hypertension (11.8%) and diabetes (3.8%). Dyspnoea (4.5%), myalgia (4.2%), cough (3.1%) and runny nose (3.1%), were the most frequent signs and symptoms. Only 19.7% of patients reported vaccination against COVID-19. Respiratory (26.3%), musculoskeletal (25.3%), endocrinology (12.1%), cardiovascular (11.1%) and infectious (11.1%) were the most frequents pathologies among patients. The presence of No Comorbidities was significantly associated as a protective factor (p = 0,014; IC 95 [0,208-0,853]; OR = 0,421). On the other hand, obesity (p = 0,010; IC 95% [1,228-5,161] OR = 2,518) and dyspnoea (p = 0,000; IC 95 [4,052-22,980]; OR = 9,649) were significantly associated as risks factors. Conclusions: A predominance of women among the population was found. Obesity was the most frequent reported comorbidity. Respiratory pathologies were the most common referred. The absence of any comorbidity shows a protective association for COVID-19. On the contrary, obesity and dyspnoea increase such association.
Perspective of dental health-care professionals during the second wave of COVID-19 pandemic: A national online survey
Authors: Nandigam Anwesh Reddy , Gummaluri Shiva Shankar , Kancharla Anil Kumar , Anumolu Venkata Naga Sri Harsha , Mohammad Sheema Tasneem , Behera Sidhartha SP
Published: August 2022

Objectives:

COVID-19 pandemic has shown a substantial impact on the entire world both physiologically and psychologically. By the hit of the second wave, which opened dangerous gates for secondary infections, apprehension was carried among health-care sectors. These secondary infections were due to decreased immunity. On the other hand, risk modifiers, such as diabetes and hypertension played a leading role in the mortality rate. A substantial number of studies have not been conducted so far regarding the impact of this second wave on dental healthcare professionals. The present study aimed to evaluate the dental healthcare professionals’ perspective levels during the second wave of the COVID-19 pandemic through a web-based survey.

Material and Methods:

A total of 853 responses were gathered by sending 15 questions in Google forms. Data collected were gathered and subjected to statistical analysis, expressed in frequency distribution and Pearson’s Chi-square test was performed.

Results:

Data obtained and projected that the study population expressed higher anxiety and stress levels, despite which was many of them showed an inclination to work during these tough times. The knowledge about secondary fungal infections like Mucormycosis, which was caused due to immune suppression, was abundant among the participants. A significant proportion conveyed the ill effect of COVID-19 on clinical practice and academics as well.

Conclusion:

Dental professionals have shown a positive perspective despite of higher stress levels and being a part of frontline workers, they are much primed to assure, educate, and treat the patients amidst the COVID-19 pandemic.
Depression and Quality of Life of Parkinson’s disease patients – A hospital-based cross-sectional study
Authors: Rajagopalan Maanasa , Ranganathan Lakshmi Narasimhan , Valarmathi S. , Govindarajulu Srinivas , Seshayyan Sudha
Published: August 2022

Objective:

The objective of this study was to assess the levels of depression among patients with Parkinson’s Disease (PD), the factors influencing their levels, and determine their influence on their Quality of Life (QoL).

Materials and Methods:

The study was conducted at the movement disorders outpatient department, Rajiv Gandhi Government General hospital, where 50 patients with diagnosed PD were enrolled. They were interviewed for their levels of depression and QoL using respective standardized depression and QoL assessment questionnaires.

Results:

Patients with PD were mostly above the age of 50 and were male. Their levels of depression ranged between normal to mild and borderline depression and their QoL scores were also moderate. Among their QoL domains, the emotional well-being, and cognition of patients were found to be more affected when compared to other domains.

Conclusion:

The prevalence and severity of depression among patients with PD were mild, but they play an important role in determining their QoL, especially the emotional well-being and cognitive performance of patients.
A Comprehensive review on antihyperglycemic phytochemicals from Western Ghats plant species and their mechanism of action
Authors: Shashikumar R. , Santhosh K.H. , Lakshmi B.S. , Ghosh Rajesh , Ravindranath B.S.
Published: August 2022

The Western Ghats (WG) is the house for ~5000 flowering plants and is one of the exceptional biodiversity and endemism hotspots among the world’s eight “hottest hotspots”. WG has also been considered a World Heritage Site by UNESCO. It holds a very high endemicity level by accommodating ~650 tree species where 352 trees are endemic. The flora of WG is also an extensive repository of medicinal plants. In an effort by the scientific community by screening and evaluating these medicinal plants, various vital phytochemicals with varied activities have been reported. This review focuses on the medicinal plant species, phytochemical compounds class, types of extraction methods, solvents used and phytoconstituents specific to the antihyperglycemic property. It also extends to bridge the information relating to the practical methods of phytochemicals extraction and evaluating compounds and validation based on various methods adopted in plants. The authors anticipate that this work may shed light on the researchers' methodologies from other regions that can be effectively adopted to WG plants to unearth the potential phytochemicals where they need further investigation and validation. The data reported and analyzed in this review also extrapolates on the phytoconstituents, efficacy and toxicity which have been extracted from the same plants found in other Asiatic regions.
“On a par with dance and plastic arts”
Authors: Купровская Е.О. , Жодловски П.
Published: August 2022

В беседе с Екатериной Купровской Пьер Жодловски рассказывает о влиянии театра и визуальных искусств на его творчество, о его пристрастии к технике «звуковых петель», которую сам он называет «кумулятивной музыкой». Также Жодловски говорит о важной роли пульсации, присутствующей в его музыке, которую он унаследовал от джаза и рока.

In a conversation with E. Kouprovskaya, Pierre Jodlowski talks about the influence of theater and visual arts on his work, about his fondness for the technique of loops, which he himself calls “cumulative music”. Jodlowski also talks about the important role of pulsation in his music, which he inherited from jazz and rock.
"To construct your own sound is… to construct yourself"
Authors: Купровская Е.О. , Комбье Ж.
Published: August 2022

В беседе с Е. Купровской Жером Комбье рассказывает о своем пути к композиторскому ремеслу, о влиянии на его творчество визуальных искусств и внеевропейских культур; рассуждает о миссии композитора, о необходимости адаптации к технологиям и философским идеям сегодняшней реальности. Речь идет о трактовке музыкального материала как последовательности различных темпоральных пространств, о равновесии между вертикалью и горизонталью, об осознании различных элементов музыкального языка как сил, обладающих способностью притяжения.

In a conversation with E. Kouprovskaya, Jérôme Combier talks about his path to composing, about the influence of visual arts and extra-European cultures on his work; discusses the composer's mission, the need to adapt to technology and philosophical ideas of today's reality. The discourse concerns the interpretation of musical material as a sequence of different temporal spaces, about the balance between vertical and horizontal, about the interpretation of various elements of musical language as forces with the ability of attraction.
Ultrasound and Microwave-assisted Enzymatic Catalysis of Xylitol Monooleates
Authors: Aguiar Moraes Acácio Raphael , O. Lemos Marcos P. , Rodrigues Rufino Alessandra
Published: August 2022

The increasing social and political pressures related to the environmental problems generated by traditional chemical processes involving the use of toxic solvents, strong acids, and high energy demand suggest utilization of clean methodologies that follow the precepts established by green chemistry. Enzymatic catalysis promotes enantioselective syntheses operating under mild condi-tions of temperature and pressure. The process, however, requires elevated times of reactions and the use of high-cost immobilized derivatives. These consequences usually become obstacles to industrial application of such syntheses. Using of ultrasound and microwaves as alternative heat-ing sources in the enzymatic catalysis, it is possible to overcome these problems besides leading to satisfactory yields and allowing the reduction of solvent volume. In this work, esterification reactions of oleic acid were performed to obtain xylitol monooleate by using alternative method-ologies which agree with the precepts of green chemistry. Yield of 96,5% employing microwave heating and 74,6% with ultrasound were obtained, both using the amount of 2,5 mL of solvent, half of the previous reports. In microwave heating, the reuse of the immobilized enzyme was pos-sible till the third use, retaining yields above 77%. The results showed that was possible to reduce the mass of the catalyst, the volume of the solvent, and the energy consumed in the process with-out significant loss related to the reaction yield.
A borindolizine platform for the design of fluorophores with tunable emissions
Authors: Yudin Andrei , Apte Chirag , Heller Nicholas , Marr Adam , Jorner Kjell , Aspuru-Guzik Alan
Published: August 2022

A new boron-containing heterocyclic scaffold – borindolizine – is reported as a new heterocyclic scaffold with broadly tunable fluorescence and a high Stokes shift. Two classes of emitters were synthesized through rational scaffold changes resulting in blue-emitting carboxyborindolizines (λmax,em = 431 – 459 nm) and green emitting aryl borindolizines (λmax,em = 488 – 519 nm). Experimental structure-emission trends were used to validate a computational spectral prediction model and subsequently used to design a red-emissive fluorophoric scaffold. A red-emissive (λmax,abs = 370 nm, λmax,em = 635 nm) isoquinolyl borinidolizine was synthesized in excellent agreement with the theoretical emission (λmax,em = 621 nm). These results establish borindolizine as a highly attractive class of fluorescent heterocycle with a highly tunable emission, allowing for custom fluorophore synthesis.
Assessment of the generalization abilities of machine-learning scoring functions for structure-based virtual screening
Authors: Zhu Hui , Yang Jincai , Huang Niu
Published: August 2022

In structure-based virtual screening (SBVS), it is critical that scoring functions capture protein-ligand atomic interactions. By focusing on the local domains of ligand binding pockets, a standardized pocket Pfam-based clustering (Pfam-cluster) approach was developed to assess the cross-target generalization ability of machine-learning scoring functions (MLSFs). Subsequently, 11 typical MLSFs were evaluated using random cross-validation (Random-CV), protein sequence similarity-based cross-validation (Seq-CV), and pocket Pfam-based cross-validation (Pfam-CV) methods. Surprisingly, all of the tested models showed decreased performances from Random-CV to Seq-CV to Pfam-CV experiments, not showing satisfactory generalization capacity. Our interpretable analysis suggested that the predictions on novel targets by MLSFs were dependent on buried solvent-accessible surface area (SASA)-related features of complex structures, with larger predicted binding affinities on complexes owning larger protein-ligand interfaces. By combining buried SASA-related features with complex-specific patterns that were only shared among structurally similar compounds in the same cluster, random forest (RF)-Score attained a good performance in Random-CV test. Based on these findings, we strongly advise to assess the generalization ability of MLSFs with Pfam-cluster approach and to be cautious with the features learned by MLSFs.
Amplitude Reordering Accelerates the Adaptive Variational Quantum Eigensolver Algorithms
Authors: Lan Zhihao , Liang WanZhen
Published: August 2022

The variational quantum eigensolver (VQE) algorithm can simulate the chemical systems such as molecules in the noisy intermediate-scale quantum devices and shows promising applications in quantum chemistry simulations. The accuracy and computational cost of the VQE simulations are determined by the underlying Ansätze. Therefore, the most important issue is to generate a compact and accurate Ansätze which requires a shallower parametric quantum circuit and can achieve an acceptable accuracy. The newly developed adaptive algorithms (AAs) such as the adaptive derivative-assembled pseudo-Trotter VQE (ADAPT-VQE) can solve this issue via generating compact and accurate Ansätze. However, these AAs show very low computational efficiency because they require a large number of additional measurements. Here we propose an amplitude reordering (AR) strategy to accelerate the promising but expensive AAs by adding operators in a "batched" fashion in a way that their order is still quasi-optimal. We first introduce the AR method into ADAPT-VQE and build the AR-ADAPT-VQE algorithm. We then endow the energy-sorting VQE (ES-VQE) algorithm with the adaptive feature, and introduce the AR into AES-VQE to form the AR-AES-VQE algorithm. To demonstrate the performance of these algorithms, we calculate the dissociation curves of three small molecules, LiH, linear BeH2, and linear H6, by using (AR-)ADAPT-VQE and (AR-)AES-VQE algorithms. It is found that all the AR-equipped AAs (AR-AAs) can significantly reduce the number of iterations and subsequently accelerate the calculations with a speedup of up to more than ten times without the obvious loss of the accuracy. The final Ansätze generated by the AR-AAs not only avoids extra circuit depth but also maintains the computational accuracy, sometimes the AR-AAs even outperforms their original counterparts.
Las películas que nos enseñan. Entrevista con Jorge Eslava
Authors: Cabrejo José Carlos
Published: August 2022

Conversamos con el escritor y educador sobre el cine como medio de educación tanto de escolares como de universitarios, a propósito de su libro Mirador de ilusiones, que realza el poder de las películas como una herramienta para aprender a sumergirnos en la cultura de paz y otras dimensiones dignas de la humanidad. Entrevista realizada por José Carlos Cabrejo.
Impact of kidney biopsy on the management of patients in the rheumatology department: retrospective study
Authors: Kokhanchuk Valeria A. , Skvortsov Alexey V. , Shchegoleva Elena M. , Kuznetsova Ekaterina I. , Novikov Pavel I. , Stoliarevich Ekaterina S. , Varshavsky Vladimir A. , Moiseev Sergey V. , Bulanov Nikolay M.
Published: August 2022

Background. Kidney involvement is a common manifestation of the systemic autoimmune rheumatic diseases. Kidney biopsy is the gold standard for the diagnosis of kidney diseases, however this method has not yet become the standard-of-care in rheumatology practice.
Aim. To assess the diagnostic value of kidney biopsy in the management of patients of the rheumatology department.
Materials and methods. In this retrospective observational study we analyzed the medical documentation including kidney morphology findings in the patients of the Department of Rheumatology at Tareev Clinic of Internal Diseases. All patients included in the research had signs of kidney involvement and had undergone needle biopsy of the kidney or re-evaluation of the kidney tissue received previously.
Results. From June 2016 to October 2021, 3110 patients were admitted to the rheumatology department. Among them 63 (2%) underwent kidney biopsy and were included in the study. Twenty (32%) were male. Mean age was 42.513.9 years. The most common preliminary diagnoses before kidney biopsy were ANCA-associated vasculitis (n=17), systemic lupus erythematosus (n=12), and AA-amyloidosis associated with inflammatory joint diseases (n=7). In 14 (27%) patients diagnosis was unspecified at the time of biopsy. Among 49 patients with established preliminary diagnosis morphological findings were in line 38 (78%) with the pre-liminary diagnosis. However, in 11 (22%) patients morphological findings resulted in the change of the diagnosis. In all 14 patients with unspecified condition kidney biopsy helped to establish clinical diagnosis. Ultrasound evaluation demonstrated hematoma formation in 18 (31%) patients, and among them two required blood component transfusions.
Conclusion. Our study demonstrates significant value and safety of kidney biopsy in the patients with autoimmune rheumatic conditions. We suggest that kidney biopsy should be implemented in the management of this category of patients.
Avant-garde Approach to Life: Reviewing the Current Applications of 3D Bioprinting
Authors: Nawaz Iqra , Nawaz Yashfa , Nawaz Eisha
Published: August 2022

Introduction: The promise of bioprinting tissue constructs that could potentially serve the same function in the human body as native tissues has taken the world of regenerative medicine by storm. The current review describes system-wide clinical applications of three-dimensional (3D) bioprinting and aims to address ethical and social considerations, while also discussing the scope of this technology in the near future.
Discussion: 3D bioprinting is believed to present new approaches to conventional treatment, offering the advantage of customization and on-time availability. It facilitates simultaneous deposition of appropriate bioinks and biomaterials onto scaffolds which can then be employed to develop tissue fabricates that can potentially mimic native tissues in both structure and functionality. It has been extensively employed to regenerate viable tissue constructs of skin, bone, cartilage, vasculature, myocardial tissue and heart valves, nervous tissue, lung and tracheal tissue, liver, pancreatic, and corneal tissue.
Conclusion: To obviate the current restrictions associated with this technology, it is imperative to understand where we currently stand in terms of current clinical applications of 3D bioprinting. This technology is anticipated to contribute significantly to the fields of tissue engineering and regenerative medicine (TERM), where it can be employed to fabricate functional tissues that can simulate their counterparts in the human body.
Relevance: The increasing disparity between organ demand and supply as well as the shortcomings associated with antiquated approaches to treatment call for utilizing 3D bioprinting to develop viable tissue constructs.
Violation of finite approximability for single-coefficient commutant equations
Authors: Дурнев Валерий Георгиевич , Зеткина Алена Игоревна
Published: August 2022

В работе построено разрешенное относительно неизвестных уравнение в свободной группе ранга 2, левая часть которого принадлежит коммутанту (имеет нулевую сумму показателей по каждой переменной), а правая часть - простейший коммутатор, не имеющее решения в этой группе, но имеющее решение в любом конечном гомоморфном образе этой группы.

We construct an equation (resolved with respect to unknowns) such that (i) it has no solution in $F_2$ (a free group of rank 2), but (ii) it has a solution in any finite homomorphic image of $F_2$. The left-hand-side of this equation belongs to the derived subgroup (i.e. has zero sum of exponents in each variable), while its right-hand-side is the commutator of two generators of $F_2$.
Modeling of the partial fixed point operator
Authors: Секорин Всеслав Станиславович
Published: August 2022

В работе рассмотрены различные семантики частичной фиксированной точки для бесконечных алгебраических систем. Показано, что операторы частичной фиксированной точки рассматриваемых семантик можно промоделировать оператором инфляционной фиксированной точки в тех алгебраических системах, в которых есть строгий частичный порядок со сколь угодно длинными цепями.

We consider various semantics of partial fixed point (PFP) operator for infinite structures. We consider infinite structures those contains partial order with chains of arbitrary length. We establish that considerable semantics can be modeled by inflationary fixed point operator.
On Abel summation for Laplace transform of the homogeneous functions in $R^n$
Authors: Архипов Сергей Викторович
Published: August 2022

В статье рассматриваются однородные функции, имеющие вид $\theta \left(\tau \right)\left|t\right|^{\alpha },$ гдепорядок однородности $\alpha >-n$, а $\theta \left(\tau\right)$ - функция на единичной сфере $S^{n-1}=\left\{t{\in}R^n, \left|t\right|=1\right\}$. При вычислении преобразования Лапласа этих функций с носителем востром конусе необходимо получить их явное представление. Это достигается суммированием интегралов по Абелю, а также применением Фурье-анализа на сфере, позволяющих свести вычисления к преобразованиям гипергеометрических функций, необходимых для вычисления пределов при $\varepsilon \rightarrow 0.$ В статье представлены формулы преобразования Лапласа однородных функций для различных функциональных пространств на единичной сфере.

The article discusses homogeneous functions of the form $\theta \left(\tau \right)\left|t\right|^{\alpha }$, which aredetermined by the order of homogeneity $\alpha >-n$, as well as by the function $\theta \left(\tau \right)$ on the unit sphere $S^{n-1}=\left\{t{\in}R^n,\left|t\right|=1\right\}$. When calculating the Laplace transform of these functions supported in a sharp cone, it is necessary to obtain an explicit representation. This is achieved by summing integrals according to Abel, as well as by applying Fourier analysis on the sphere, which will allow to bring calculations to transformations of hypergeometric functions necessary to calculate the limits as $\varepsilon \rightarrow 0$. The article presents formulas for the Laplace transform of homogeneous functions for various function spaces on the unit sphere.
Ranking of normality tests
Authors: Скрынников Андрей Александрович
Published: August 2022

В работе предложен новый подход, который позволяет провести сравнительный анализ критериев проверки отклонения от нормального закона.Использование в качестве альтернативных гипотез серии распределений, последовательно сходящихся к нормальному закону, позволило ввести интервальную шкалу, по которой можно определить не только какой из сравниваемых критериев лучше, но и насколько лучше.

The paper proposes a new approach that allows a comparative analysis of the normality tests.Using a series of distributions that consistently converge to the normal law as alternative hypotheses allowed us to introduce an interval scale by which it is possible to determine not only which of the compared criteria is better, but also how much better.
TỔNG HỢP PHỨC TITANIUM PEROXIDE VÀ KHẢO SÁT HOẠT TÍNH XÚC TÁC CỦA HỆ TiO2/g-C3N4
Authors: Đặng Thị Ngọc Hoa , Nguyễn Nguyen Đức Hồng
Published: August 2022

Bài báo này trình bày kết quả tổng hợp phức titanium peroxide và hoạt tính quang xúc tác của hệ TiO2/g-C3N4. Vật liệu được đặc trưng bằng phương pháp quang phổ phản xạ khuếch tán tử ngoại khả kiến, nhiễu xạ tia X, hiển vi điện tử quét, hiển vi điện tử truyền qua và phổ hồng ngoại. Phức titanium peroxide có hàm lượng TiO2 cao và hệ TiO2/g-C3N4 với tỷ lệ 1:1 (kl) có hoạt tính xúc tác quang tốt. Đây là vật liệu tiềm năng cho xử lý nước thải ô nhiễm.
TỔNG HỢP VẬT LIỆU NANO LaFeO3 BẰNG PHƯƠNG PHÁP THỦY NHIỆT VÀ ỨNG DỤNG
Authors: Võ Văn Tân , Nguyễn Thị Liên
Published: August 2022

Nguyên liệu ban đầu gồm La(NO3)3 và Fe(NO3)3 theo tỷ lệ mol 1:1, etanol và isopropanol được thủy nhiệt ở 150 °C trong 80 phút, rồi nung ở 800 °C trong 2 giờ. Sản phẩm được đặc trưng bằng các phương pháp: phân tích nhiệt (TGA), nhiễu xạ tia X (XRD), tán xạ năng lượng tia X (EDS), hồng ngoại (IR) và hiển vi điện tử quét (SEM). Vật liệu nano LaFeO3 thu được là đơn pha, dạng mảnh, kích thước trung bình 30–50 nm. Hoạt tính quang xúc tác xử lý xanh metylen dưới ánh sáng mặt trời bằng vật liệu nano LaFeO3 trong 75 phút cho hiệu suất 86,50%. Vật liệu nano LaFeO3 hấp phụ Cr(VI) trong dung dịch ở pH 6,3 trong khoảng thời gian 75 phút cho hiệu suất 57,70%.
A protective role forDrosophilaFilamin in nephrocytes via Yorkie mediated hypertrophy
Authors: Koehler Sybille , Huber Tobias B , Denholm Barry
Published: August 2022

Podocytes are specialized epithelial cells of the kidney glomerulus and are an essential part of the filtration barrier. Because of their position, they are exposed to constant biomechanical forces such as shear stress and hydrostatic pressure. These forces increase during disease, resulting in podocyte injury. It is likely podocytes have adaptative responses to help buffer against deleterious mechanical force and thus reduce injury. However, these responses remain largely unknown. Here, using theDrosophilamodel, we show the mechanosensor Cheerio (dFilamin) provides a key protective role in nephrocytes. We found expression of an activated mechanosensitive variant of Cheerio rescued filtration function and induced compensatory and hypertrophic growth in nephrocytes depleted of the nephrocyte diaphragm proteins Sns or Duf. Delineating the protective pathway downstream of Cheerio we found repression of the Hippo pathway induces nephrocyte hypertrophy, whereas Hippo activation reversed the Cheerio-mediated hypertrophy. Furthermore, we find Yorkie was activated upon expression of active Cheerio. Taken together, our data suggest that Cheerio acts via the Hippo pathway to induce hypertrophic growth, as a protective response in abnormal nephrocytes.
Measuring cystic fibrosis drug responses in organoids derived from 2D differentiated nasal epithelia
Authors: Amatngalim Gimano D , Rodenburg Lisa W , Aalbers Bente L , Raeven Henriette HM , Aarts Ellen M , Sarhane Dounia , Spelier Sacha , Lefferts Juliet W , Silva Iris AL , Nijenhuis Wilco , Vrendenbarg Sacha , Kruisselbrink Evelien , Brunsveld Jesse E , van Drunen Cornelis M , Michel Sabine , de Winter-de Groot Karin M , Heijerman Harry G , Kapitein Lukas C , Amaral Magarida D , van der Ent Cornelis K , Beekman Jeffrey M
Published: August 2022

Cystic fibrosis is caused by genetic defects that impair the CFTR channel in airway epithelial cells. These defects may be overcome by specific CFTR modulating drugs, for which the efficacy can be predicted in a personalized manner using 3D nasal-brushing–derived airway organoids in a forskolin-induced swelling assay. Despite of this, previously described CFTR function assays in 3D airway organoids were not fully optimal, because of inefficient organoid differentiation and limited scalability. In this report, we therefore describe an alternative method of culturing nasal-brushing–derived airway organoids, which are created from an equally differentiated airway epithelial monolayer of a 2D air–liquid interface culture. In addition, we have defined organoid culture conditions, with the growth factor/cytokine combination neuregulin-1βand interleukin-1β, which enabled consistent detection of CFTR modulator responses in nasal-airway organoid cultures from subjects with cystic fibrosis.
A review on lungs disease detection using image processing
Authors: Tikendra Sahu , Aakanksha S. Choubey
Published: August 2022

The global fitness company estimates that by 2030, Chronic Obstructive Pulmonary Disease (COPD) will be the third leading cause of death in the world. Computerized Tomography (CT) of the lungs includes a number of structures that may be important in the prognosis and evaluation of lung disease. CT images of the lungs show a section of the chest that constitutes a large number of systems, including blood vessels, arteries, respiratory vessels, pulmonary pleura, and parenchyma, each with its own information. For this reason, the phasing of the lung systems is very important for the analysis and diagnosis of lung diseases. Segmentation is an important step in the photographic structure for the correct diagnosis of lung disease, as it delimits lung systems on CT images. Of course, imaging strategies can aid in computer analysis if the lung area is properly obtained. After the segmentation procedure, an automatic technique is used to identify possible diseases on CT scans of the lungs so the radiologist can focus on the prognosis of the patient. Several studies have shown promising results in detecting violations.
Face mask detection with temperature check
Authors: Rupali Sharma , Abha Chaubey , Sidhhartha Chaubey
Published: August 2022

The coronavirus (COVID-19) pandemic is causing a worldwide health catastrophe, so according to the World Health Organization (WHO), wearing masks in public is an effective safety method. The COVID-19 pandemic has forced governments around the world to impose quarantines to prevent transmission of the virus. According to reports, wearing masks in public does reduce the threat of transmission of the virus. An efficient and cost-effective way to use Artificial Intelligence (AI) to create a secure environment in a manufacturing environment. A hybrid model for using a deep and classic face mask detection device will be proposed. The face mask detection dataset includes the mask, and without mask photos, it uses the Open-Source Computer Vision Library (OpenCV) to detect faces in real-time from the stay circulation through the webcam. It uses the dataset to build a computer vision COVID-19 face mask detector using Python, OpenCV, TensorFlow, and Keras. Using computer vision and deep learning, the goal is to understand whether a character in a picture or video stream is wearing a mask or not using computer vision and deep learning.
Facebook addiction among prospective teachers - a study conducted in kanyakumari district
Authors: D. R. Robert Joan
Published: August 2022

Facebook is very familiar in the country over the past decade. It helps to connect global citizens through a social network on the Internet. Many people use the Facebook network to communicate and exchange opinions. There are many positive aspects, although it spoils some individuals' lives. One of the main areas that can become aware of is time. The first and vital thing is that "it will kill the viewers' time" because it provides them with entertainment. Gradually, this causes viewers to listen more often to the posts of others. This is due to the desire to know others; they may be friends or relatives. The aim of this paper is to investigate Facebook addiction among prospective teachers and to find the difference between potential teachers in their dependence on Facebook in relation to marital status, place of residence, number of family members, father's profession, and mother's profession. This paper uses a survey method to determine the dependence of future teachers on Facebook. The paper consists of 60 samples of the population of a teacher training college. It uses the Facebook Addiction Scale tool for the present study. The conclusion shows that there is no significant difference between potential teachers in their dependence on Facebook in terms of marital status, place of residence, number of family members, father's profession, and mother's profession. Many of them use Facebook to share their daily activities with friends. This causes eagerness among recipients and senders. Thus, other background variables did not affect the use of Facebook by potential teachers.
Assessment of toxin-producing genes in Aspergillus species from traditional
herbal products in Khon Kaen province, Thailand using molecular method
Authors: Jitjak W.
Published: August 2022

A large number of traditional herbal products from medicinal plants are available in local
markets. However, the risk of fungal contamination especially toxigenic Aspergillus
species, Aspergillus niger and Aspergillus flavus was potentially possible. Thus, this study
targeted to investigate the prevalence of A. niger and A. flavus and the occurrence of genes
encoding toxins, aflatoxins and ochratoxin A among the fungi using the molecular method
in 33 herbal products randomly collected from local markets in Khon Kaen province,
Thailand. Based on the identification using DNA sequences of the internal transcribed
spacer region (ITS), there were two Aspergillus species, A. niger and A. flavus, with
prevalence rates of 73.6% and 0.1% respectively. The genes related to aflatoxins and
ochratoxin A were undetectable in all isolates. This study suggested the products were
naturally contaminated with the fungi, but they were safe from the toxigenic A. niger and
A. flavus.