bluuebunny/crossref_metadata_2025 huggingface dataset:
New Verse for a Familiar Song: Small Molecule Inhibitors for MET exon 14 Skipping Non-Small Cell Lung Cancer
Authors: Le Xiuning , Heymach John V.
Published: September 2020

MET exon 14 skipping alterations (METex14) represent one of the newest discovered driver oncogene alterations for non-small cell lung cancer (NSCLC), which serve to define a distinct elderly patient population. New challenges in detection and treatment have emerged.

In the last 15 years, the successes of tumor molecular profiling and therapeutic stratification in patients with advanced-stage disease have made NSCLC a poster child in the era of precision medicine. Each of the oncogenic drivers defines a distinct patient population. The selection of treatments based on oncogenic drivers such as EGFR, ALK, and ROS1, among others, has been transformative in terms of the duration and quality of life for patients with NSCLC receiving effective inhibitors. METex14 have emerged as one of the newest additions of driver oncogenes for NSCLC.
The digitalisation of stationery retail and its urban effects
Authors: Ribbeck-Lampel Juliane
Published: September 2020

In the study of planning, the causal links between technological developments and the transformation of spatial and urban structures are of high social relevance. They have been increasingly examined since the late-twentieth century. However, scant attention has been paid to spatial interactions resulting from the digitalisation of all areas of life and work as well as the continuing advance of information and communication technologies. In short, there is a lack of verified studies and results regarding the effects of digitalisation on urban space. The urban function of retail can be used as an example to illustrate spatial changes promoted by technological developments, for two distribution channels that are moulded by digitalisation and are spatially relevant – physical retail and the growing field of e-commerce – are increasingly being intertwined. This paper presents the initial findings of an exploratory study into the spatial distribution patterns of selected developments in physical retail that are significantly influenced by digitalisation. Using a multi-stage methodology, more than 800 articles from online news portals pertaining to the year 2018 were analysed, categorised and evaluated with respect to spatial relevance, potential for spatial influence and the impact of digitalisation.
Are Shadow Economy and Corruption in US States Substitutive or Complementary? An Empirical Investigation
Authors: GÖKÇEKUS Ömer , SCHNEIDER Friedrich
Published: September 2020

An empirical investigation of the 50 US States shows that the relationship between shadow economy and corruption is negative (substitutive) when the shadow economy is relatively small; it is positive (complementary) when the shadow economy is large. According to the robust regression results for 50 American states between 2001 and 2008, the turning point from negative to positive is when the shadow economy of a state is at 7.61 of its GDP. Shadow economy and corruption are first substitutive and then complementary. The lesson to learn is that there is no simple anti-corruption policy rule if one takes into account the varying interaction between corruption and the shadow economy.
covid 19 indirect detection thru rise of 100nm filter fluid resistance v2
Authors: Nevery Ladislav
Published: September 2020

By passing saliva sample thru 150nm filter to remove particles larger than avg 125nm sized covid 19 virus particles and concentrating resulting fluid to very small 1 mm2 area of 110nm filter. Pores in this small area should be clogged up fast raising filter air/fluid resistance. Due to high virus density 5.2 log10 ml saliva of infected person should clogg filter much faster than healthy person. Test is setup in such way that we let gravity pass 2l of fluid thru clogged filter and record rate of drops from its bottom as audio on mobile phone placed bellow glass cup. rate of drops thru clogged filter should be measurably slower than clean filter.
Geostrategic Renewable Energy Transition in Turkey: Organizational Strategies Towards an Energy Autonomous Future
Authors: Dolunay Özge
Published: September 2020

The geographical location of Turkey in the Asia Minor places the country in a delicate geostrategic position determined by its history, ideological structure, politics and energy economy. The Turkish government has defined its main energy strategies with the goal of reaching 30% renewables by 2023. Key strategies declared are the prioritization of energy supply security, the consideration of environmental concerns, and an increase in efficiency and productivity through the establishment of transparent and competitive market conditions through reform and liberalization. This article analyses the renewable energy (RE) transition of Turkey from a fully centralised energy management model towards a system of partially centralization through the unbundling of utility companies. Analysis will utilize Michael Mann’s theory on the four sources of social power as an alternative organizational means of social control and the interrelations of ideological, economic, political and military power. The recent history of Turkey’s RE transition and government plans for sector development will be investigated from a socio-spatial and organizational perspective. Furthermore, the way in which these socio-spatial relations have been shaping electricity market liberalization and the preparedness of the state to share its power with non-state actors is discussed. The potential of a centralised RE management model to inspire ‘decentralised’ RE management in other geographies is considered. In conclusion, key factors in the organisation of the (de)centralised electricity transitions are found to be dependent on history, geography, and overlapping relations of social power.
UKRAINIAN REVOLUTION OF XX–XXI CENTURIES: HISTORICAL AND LEGAL COMPARATIVE STUDY
Authors: Kotendzhy E.
Published: September 2020

The paper analyses the revolutionary events of XX–XXI centuries in Ukraine, in particular, the prerequisites, causes, and consequences of social, political and economic nature, the historical, political and legal experience of the Ukrainian Revolution of 1917–1921, the Orange Revolution of 2004 and the Dignity Revolution of 2014. By carrying out a comparative legal analysis the author comes to the conclusion that the above mentioned processes are characterized not only by the same goal, the basis of which is the idea of social and national liberation, but also by such concepts as human centrism, their anti-imperial, national, and state orientations. On the other hand, attention is also focused on the distinctive features of the revolutions mentioned, such as different external and internal political circumstances behind them and the international legal reaction to the revolutionary events that took place in our country.

Thus, the article outlines the challenges of today's Ukrainian humanities through the prism of an average human being's role in the revolutionary process in Soviet times, identifies the impact of these phenomena on the individual, makes an attempt to find common features of political and legal reaction to such events from both Ukrainian society and the ruling circles of some neighboring states.

The paper proves the complete scientific inability of a number of Russian imperial myths, namely the desire to present Russian-Ukrainian conflicts as "civil wars", the attempts of Russian historiography to "incorporate" the Ukrainian Revolution of 1917–1921 into the all-Russian revolutionary process, the desire to characterize the 2014 Revolution of Dignity as a "coup d'etat", etc.

On the basis of the comparative analysis, the author explains why the Ukrainian state as a geopolitical reality could not happen during the revolution in the beginning of twentieth century, in contrast to the events of presence, when modern post-revolutionary Ukraine managed to withstand the struggle against the Russian occupation forces and once again avoided the tragic consequences that came to our land after the occupation.
About the so-called embryonic rickets
Authors: Pekarskaya A.
Published: September 2020

Opinions on the issue of embryonic rickets are far from agreeing. Only microscopically investigated cases can be considered as evidence.
A case of an ectopic pregnancy. Gluttony. Recovery
Authors: Hermonius A.
Published: September 2020

The patient, 32 years old, came to the author at the end of May with suspicion of some abdominal tumor. She has been married for 6 years, was not pregnant. Since the end of last year, she began to suffer from bleeding and pain in the lower abdomen. On examination, the patient turned out to be a well-fed woman. In the abdomen, a swelling is felt that goes 3 fingers above the navel and resembles a pregnant uterus when examined; dorsum of the fetus to the right, small parts to the left. The heartbeat could be heard only for a very short time, to the right of the navel, and upon repeated auscultation, it was not heard at all. The vaginal part is soft and loosened. Resistance is felt in the anterior and posterior fornix, which is softer than the fetal head. Diagnosis: pregnancy, complicated by presentation of the child's place or endometritis.
On the question of the treatment of extrauterine blood tumor
Authors: Krasnopolskiy F.
Published: September 2020

The author reports 3 cases of extrauterine blood tumor; in the first two cases, surgical treatment was used (incision of the tumor through the vagina), in the third - expectant treatment.
O mito do “éxito” escolar das rapazas
Authors: Iglesias Galdo Ana , Ballarín Domingo Pilar
Published: September 2020

A aparente igualdade entre rapazas e rapaces nas aulas oculta camiños históricos diferentes, marcados por relacións de xénero desiguais, que persisten nelas de forma sutil. Baixo a sospeita de que tras o discurso do “éxito escolar das rapazas” se alimente a preocupación dos que conciben –moitos máis dos que o nomean– que o mellor servizo das mulleres á sociedade (maternidade, crianza, coidados familiares e traballo doméstico en xeral) se pode ver minado polo seu éxito profesional –cuestión que recobra novo valor cando a crise económica require fortes soportes familiares para xestionar a miseria social–,apelaremos ás contribucións feministas para comprender mellor a que se está a denominar “éxito”, tarefa que entendemos prioritaria para desestabilizar algúns dos supostos que, coma este, están a imposibilitar a educación para a igualdade.
Factores de discriminación de xénero na escola no contexto da globalización
Authors: Sánchez Bello Ana
Published: September 2020

O fortalecemento do proceso de globalización ten sido posible en confluencia co apoio do sistema educativo cando este asume unha posición na que a hexemonía patriarcal é a norma, e as actitudes e comportamentos considerados como femininos se devalúan. Nesta situación, o profesorado pode encarar as relacións que se desenvolven na aula como unha parte clave dun proceso educativo que fomenta o desenvolvemento das personas cara a autonomía e as prácticas colaboradoras, tanto no eido público como no ámbito privado. Co obxecto de desenvolver unha proposta de aprendizaxe en relación, dende as escolas ponse de relevo a necesidade dunha revisión crítica dos valores e actitudes que, como parte da sociedade, queremos que os centros educativos ensinen: reducir o nivel de violencia e eliminar os estereotipos de xénero. Estas propostas teñen por finalidade promover relacións equitativas entre mulleres e homes nun contexto de globalización.
Ana Lúcia Cunha Fernándes (2012). A construçâo do conhecimento pedagógico: análise comparada de revistas de educaçâo e ensino; Brasil- Portugal, 1880-1930
Authors: Costa Rico Antón
Published: September 2020

Recensión de libro: Ana Lúcia Cunha Fernández (2012). A construçâo do conhecimento pedagógico: análise comparada de revistas de educaçâo e ensino; Brasil-Portugal, 1880-1930.
Xosé Ramón Iglesias Veiga (2013). Arquitectura e indianos na cidade de Vigo e bisbarra
Authors: Malheiro Gutiérrez Xosé Manuel
Published: September 2020

Recensión do libro: Xosé Ramón Iglesias Veiga (2013). Arquitectura e indianos na cidade de Vigo e bisbarra.
Rosa María Cid Galante (2013). A escola normal de mestras de Ourense (1870-1970). A súa orixe e os seus emprazamentos
Authors: Cid Fernández Xosé Manuel
Published: September 2020

Recensión de libro: Rosa María Cid Galante (2013). A escola normal de mestras de Ourense (1870-1970). A súa orixe e os seus emprazamentos.
Julia Varela Fernández & Ángel Juan Gordo López (coords.) (2013). “Mujeres y cambio social”, Papers. Revista de Sociología 98/4
Authors: Iglesias Galdo Ana
Published: September 2020

Recensión de libro: Julia Varela Fernández & Ángel Juan Gordo López (coords.) (2013). “Mujeres y cambio social”, Papers. Revista de Sociología 98/4.
Acquaintance, approach and application of pharmacovigilance: questionnaire based study at a tertiary care teaching hospital in Dhaka
Authors: Nasir Morshed , Zahan Tahmina , Farha Nadia , Chowdhury A. S. M Salauddin
Published: September 2020

Background: Pharmacovigilance is proven as an effective monitoring mechanism for safety and efficacy of pharmaceutical products with the assistance of physicians, pharmacists, nurses, and other healthcare professionals to avoid undue physical, mental and financial suffering of patients. Thus, this study was conducted to assess awareness of pharmacovigilance among the healthcare service providers to evaluate the acquaintance, approach application (3A) of judicial reporting of ADRs and pharmacovigilance in a tertiary care teaching hospital in Dhaka.Methods: A pre-tested questionnaire-based study was done among the 5th year medical students, interns, doctors and nurses of Holy Family Red Crescent Medical College, Dhaka, Bangladesh to assess the overall status of acquaintance (knowledge), approach (attitude) and application (practice) pharmacovigilance. Total 417 questionnaires were distributed and 389 were included as valid, compiled and analysed using SPSS version 25.0.Results: Among the respondents, almost 78% of the nurses responded the right answers and doctors responded the lowest 29% on average. The average percentage of approach and application of pharmacovigilance was low in all the respondent groups. The poorest outcome was observed about reporting an adverse drug reactions (ADR) form by all respondents as 01% to 08%.Conclusions: The overall status of pharmacovigilance in a tertiary teaching hospital was found paradoxically low, that revealed the necessity of much more initiatives at the undergraduate and postgraduate academic curriculum and intensive motivation, training, monitoring should be addressed to ensure the safety of medication, rationality of drug use and accomplish the national pharmacovigilance programs.
A study of phonosurgeries in vocal dysfunction in Salem district
Authors: Mahendran K. , Praveen Kumar M.
Published: September 2020

Background: Phonosurgery essentially is surgery defined to improve or restore the voice. The objective of the study was to analyze and categorize the various benign lesions of the vocal cord causing vocal dysfunction requiring phonosurgeries, to analyze the incidence and distribution of cases according to age, sex, and etiology among the patients who require intense medical and voice therapy with surgical intervention.

Methods: This prospective study was conducted in fifty patients with vocal dysfunction from the ear, neck and throat (ENT) outpatient department of Otorhinolaryngology, Mohan Kumaramangalam Government General Hospital, Salem in the year September 2018 to October 2019 who failed conservative medical and voice therapy requiring phonological procedure were included in this study. Phonomicrosurgery was done for the patients with benign vocal fold mucosal disorders and medialization laryngoplasty using Gore-Tex was done for the patients with unilateral vocal cord palsy causing vocal dysfunction.

Results: The present study on phono surgery concludes vocal polyp is the commonest benign lesion of the vocal cord that constitutes 40% in our study population. Males are affected more than females. Proper investigation of voice and larynx provides the exact pathological nature of the lesion and determines the timing of surgical intervention.

Conclusion: Most of the patients who underwent medialization laryngoplasty using Gore-Tex also had a good outcome at the end of the voice therapy.

 
A retrospective study of neurological recovery following posterior stabilization for spine instability in tertiary care hospital, Chengalpattu district
Authors: Selvaraj R. , Nagappan K. , Kumar Aravind , Vivek K.
Published: September 2020

Background: Spinal instability is defined as the loss of the ability of the spine under physiological loads to maintain relationships between vertebrae in such a way that the spinal cord or nerve roots are not damaged or irritated, and deformity or pain does not develop. The objective was to study the neurological recovery following posterior stabilization for lumbar spine instability.

Methods: This retrospective study was conducted in the Department of Orthopaedics, Karpaga Vinayaga Institute of Medical Sciences and Research Centre, Chengalpattu district, Tamil Nadu, India. (KIMS & RC). Study duration was from January 2020 to February 2020 (2 months). Patients admitted with spinal instability with neurological deficit, treated with instrumentation and fusion will be study participants were 30 patients.

Results: In our study, Denis pain scale showed that 40% of patients had minimal pain, 40% of patient had moderate pain and 20% had moderate to severe pain with significant changes in daily activities, the Denis work assessment scale showed that 33.33% of patients had unable to return to the previous job but can able to work full time with job modification.

Conclusions: The most important factor responsible for prognosis and neurological recovery is the neurological status at the time of injury. Surgical decompression and stabilization with fusion improves the neurological recovery especially in incomplete cord lesions.
About quantifying small color differences in digital images
Authors:   Technological Design Institute of Scientific Instrument Engineering SB RAS, Palchikova I.G. , Smirnov E.S. ,   Technological Design Institute of Scientific Instrument Engineering SB RAS, Barinova O.A. ,   The Volgograd Academy of the Russian Internal Affairs Ministry, Latyshov I.V. ,   The Saint Petersburg University of the Russian Internal Affairs Ministry, Vasiliev V.A. ,   The Volgograd Academy of the Russian Internal Affairs Ministry, Kondakov A.V. ,   The Volgograd Academy of the Russian Internal Affairs Ministry
Published: September 2020

We discuss aspects of the use and possibilities provided by three-color colorimeters or digital cameras in problems of detecting small color differences by computer vision methods. The spectral dependence of the total color differences between pairs of visually indiscernible monochromatic stimuli is experimentally revealed. An experimental setup based on the UM-2 monochromator is created for producing a digital atlas of monochromatic stimuli at 1-nm increments. The atlas serves to test the color gamut and color differentiation of cameras. It is experimentally shown that in the visible spectral range a color difference of 3 units is detected by pairs of stimuli that are unevenly distributed across the spectrum and differ in wavelengths from 1 to 6 nm. The capabilities of computer vision are tested on the examples of identifying additional texts during a technical and forensic examination of documents. A new algorithm is developed for finding and quantitatively characterizing color difference of inserts based on a digital image of the inscription. In the algorithm, the objective analysis of the image is divided into a block of color segmentation and that of color tone and color difference assessment. With such an approach, the color segmentation block performs preprocessing functions, making a border map for the classes with different colors for the subsequent calculations. The Otsu method of optimal global threshold transformation is for the first time applied to a problem of image segmentation by color saturation. The trial of the algorithm confirms its efficiency in the solution of expert tasks.
Semantic segmentation of satellite images of airports using convolutional neural networks
Authors:   State Research Institute of Aviation Systems (SSC of RF), Gorbachev V.A. , Krivorotov I.A. ,   State Research Institute of Aviation Systems (SSC of RF),   Moscow Institute of Physics and Technology (State University), Markelov A.O. ,   State Research Institute of Aviation Systems (SSC of RF),   Moscow Institute of Physics and Technology (State University), Kotlyarova E.V. ,   Moscow Institute of Physics and Technology (State University)
Published: September 2020

The paper is devoted to the development of an effective semantic segmentation algorithm for automation of airport infrastructure labelling in RGB satellite images. This task is addressed using algorithms based on deep convolutional artificial neural networks, as they have proven themselves in a wide range of tasks, including the terrestrial imagery segmentation, where they show consistently high results. A new dataset was labelled for this particular task and a comparative analysis of different architectures and backbones was carried out. A conditional random field model (CRF) was used for postprocessing and accounting of contextual information and neighborhood of objects of different classes in order to eliminate outliers. Features of the solutions applied at all preparatory stages of the algorithm were described, including data preparation, neural network training and post-processing of the training results.
Security detection of network intrusion: application of cluster analysis method
Authors:   Railway Signal and Information Engineering Department, Shandong Polytechnic, Yang W.H.
Published: September 2020

In order to resist network malicious attacks, this paper briefly introduced the network intrusion detection model and K-means clustering analysis algorithm, improved them, and made a simulation analysis on two clustering analysis algorithms on MATLAB software. The results showed that the improved K-means algorithm could achieve central convergence faster in training, and the mean square deviation of clustering center was smaller than the traditional one in convergence. In the detection of normal and abnormal data, the improved K-means algorithm had higher accuracy and lower false alarm rate and missing report rate. In summary, the improved K-means algorithm can be applied to network intrusion detection.
Earth remote sensing imagery classification using a multi-sensor super-resolution fusion algorithm
Authors:   Samara National Research University, Belov A.M. , Denisova A.Y. ,   Samara National Research University
Published: September 2020

Earth remote sensing data fusion is intended to produce images of higher quality than the original ones. However, the fusion impact on further thematic processing remains an open question because fusion methods are mostly used to improve the visual data representation. This article addresses an issue of the effect of fusion with increasing spatial and spectral resolution of data on thematic classification of images using various state-of-the-art classifiers and features extraction methods. In this paper, we use our own algorithm to perform multi-frame image fusion over optical remote sensing images with different spatial and spectral resolutions. For classification, we applied support vector machines and Random Forest algorithms. For features, we used spectral channels, extended attribute profiles and local feature attribute profiles. An experimental study was carried out using model images of four imaging systems. The resulting image had a spatial resolution of 2, 3, 4 and 5 times better than for the original images of each imaging system, respectively. As a result of our studies, it was revealed that for the support vector machines method, fusion was inexpedient since excessive spatial details had a negative effect on the classification. For the Random Forest algorithm, the classification results of a fused image were more accurate than for the original low-resolution images in 90% of cases. For example, for images with the smallest difference in spatial resolution (2 times) from the fusion result, the classification accuracy of the fused image was on average 4% higher. In addition, the results obtained for the Random Forest algorithm with fusion were better than the results for the support vector machines method without fusion. Additionally, it was shown that the classification accuracy of a fused image using the Random Forest method could be increased by an average of 9% due to the use of extended attribute profiles as features. Thus, when using data fusion, it is better to use the Random Forest classifier, whereas using fusion with the support vector machines method is not recommended.
Design and fabrication of a freeform mirror generating a uniform illuminance distribution in a rectangular region
Authors:   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Andreev E.S. ,   Samara National Research University, Byzov E.V. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Bykov D.A. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS,   Samara National Research University, Moiseev М.А. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Kazanskiy N.L. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS,   Samara National Research University, Doskolovich L.L. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS,   Samara National Research University
Published: September 2020

The design of a freeform mirror generating a uniform illuminance distribution in a rectangular region with angular dimensions of 30°x15° is presented. The design method is based on the formulation of the problem of calculating the "ray-mapping" as a Monge-Kantorovich mass transportation problem and its subsequent reducing to a linear assignment problem. We describe a mirror fabrication process with the use of milling technology and present results of experimental measurements of the light distribution generated by the mirror. The experimental results are in good agreement with the results of numerical simulations and thus confirm the manufacturability of mirrors designed by the method proposed.
Digital sorting of Hermite-Gauss beams: mode spectra and topological charge of a perturbed Laguerre-Gauss beam
Authors:   Physics and Technology Institute of V.I. Vernadsky Crimean Federal University, Volyar A.V. , Abramochkin E.G. ,   Samara Branch of P.N. Lebedev Physical Institute of Russian Academy of Sciences, Egorov Yu. ,   Physics and Technology Institute of V.I. Vernadsky Crimean Federal University, Bretsko M. ,   Physics and Technology Institute of V.I. Vernadsky Crimean Federal University, Akimova Ya. ,   Physics and Technology Institute of V.I. Vernadsky Crimean Federal University
Published: September 2020

We developed and implemented an intensity moments technique for measuring amplitude and initial phase spectra, the topological charge (TC) and orbital angular momentum (OAM) of the Laguerre-Gauss (LG) beams decomposed into the basis of Hermite-Gaussian (HG) modes. A rigorous theoretical justification is given for measuring the TC of unperturbed LG beams with different values of radial and azimuthal numbers by means of an astigmatic transformation on a cylindrical lens. We have shown that the measured amplitude and phase spectra of the HG modes make it possible to find the orbital OAM and TC, as well as digitally sorting the HG modes and then restoring the initial singular beam.
Simulating shot noise of color underwater images
Authors:   Institute for Information Transmission Problems, RAS, Shepelev D.A. ,   Moscow Institute of Physics and Technology, Bozhkova V.P. ,   Institute for Information Transmission Problems, RAS, Ershov E.I. ,   Institute for Information Transmission Problems, RAS, Nikolaev D.P. ,   Institute for Information Transmission Problems, RAS,   LLC "Smart Engines Service"
Published: September 2020

This paper considers methods for simulating color underwater images based on real terrestrial images. Underwater image simulation is widely used for developing and testing methods for improving underwater images. A large group of existing methods uses the same deterministic image transformation model ignoring the presence of noise in images. The paper demonstrates that this significantly affects the overall quality of underwater images simulation. It is shown both theoretically and numerically that the accuracy of the signal-to-noise ratio of underwater images simulated using a deterministic transformation decreases with increasing distance to the object. To solve this problem, a new model of image transformation for simulating underwater images based on terrestrial images is proposed, which considers the presence of noise in the image and is compatible with all simulating methods from the group under consideration. The paper presents the results of the simulation based on the existing and proposed models, showing that at long distances, the new results are better consistent with real data.
Ethnoepidemiology and mental health: insights from Latin America
Authors: Almeida-Filho Naomar
Published: September 2020

In this essay, I explore methodological as well as theoretical implications of an ethno-epidemiological approach, aiming to integrate research findings in mental health into new conceptual models. With this objective, I first evaluate the roots and uses of the term “ethnoepidemiology” to designate three research strategies for scientific knowledge production: type I (studies of sociocultural risk factors and ethnically defined risk groups); type II (studies of lay models of distribution and occurrence of illness in populations); type III (ethnographic studies of projects and areas of epidemiologic research). As an illustration, selected methodological features of three studies in which I have participated are presented and discussed. I then elaborate upon methodological developments derived from this experience of doing research, generating new models for transcultural transdisciplinary research of mental health practices. Lastly, I comment on some broad implications of studying mental health problems from an integrated ethnographical and epidemiological point of view, in diverse and deeply unequal societies such as those of contemporary Latin America.
Comunidades terapêuticas e a (re)manicomialização na cidade do Rio de Janeiro
Authors: Passos Rachel Gouveia , Souza de Farias Jessica , Meyre da Silva Gomes Tathiana , De Castro Lopes de Araujo Giulia
Published: September 2020

Na atual conjuntura, as ações direcionadas as pessoas que fazem uso prejudicial de álcool e outras drogas estão baseadas em uma visão moralizante que culpabiliza o indivíduo e impõe como solução o controle dos corpos sob uma base religiosa, associando o cuidado em saúde mental exclusivamente ao autocontrole e a fé. Nesse caminho, o presente artigo objetiva relacionar o crescimento do incentivo financeiro das Comunidades Terapêuticas com o projeto político que está em andamento no governo federal e na condução da política de saúde mental que vem sendo implementada no município do Rio de Janeiro desde o ano de 2017.
Avaliação da Eficiência Energética do Tribunal de Contas do Paraná, sediado em Curitiba
Authors: Moro Jeanne , Bassani Correa Pablo Cesar , Krüger Eduardo
Published: September 2020

A procura por maior eficiência energética no uso da eletricidade trouxe inúmeras iniciativas louváveis, no Brasil sob responsabilidade maior do Procel, com campanhas de conscientização dos usuários, pela etiquetagem de aparelhos eletrodomésticos até o panorama atual de certificação de edificações. O presente estudo tem como objetivo principal avaliar o nível de eficiência energética por meio dos Requisitos Técnicos da Qualidade do Nível de Eficiência Energética para Edifícios Comerciais, de Serviços e Públicos (RTQ-C/Procel) do Tribunal de Contas (TC), parte do patrimônio histórico do Estado do Paraná, localizado no Centro Cívico de Curitiba. TC é composto de dois edifícios construídos e um terceiro edifício em projeto: o Edifício Sede, o Edifício Anexo e a Ampliação do Edifício Anexo. No Edifício Sede, foram analisados indicadores de possível economia energética resultante da melhoria dos sistemas de iluminação (natural e artificial). Na ampliação do Edifício Anexo, avaliou-se a aplicabilidade do sistema de sombreamento de fachadas denominado tela tensionada. Comprovou-se que os edifícios existentes apresentam grande potencial de economia energética em sistemas de iluminação e que, ao se aprimorarem os dispositivos de sombreamento da fachada no projeto de ampliação do Edifício Anexo, podem ser alcançados maiores níveis de eficiência energética no quesito envoltória.
Does Non-Steroidal Anti-inflammatories: Does carprofen or meloxicam have fewer gastrointestinal side effects?
Authors: Fletcher Aaron Harold Andrew
Published: September 2020

PICO question

In canines, does the oral administration of carprofen, when compared to meloxicam, result in fewer gastrointestinal side effects?

 

Clinical bottom line

Category of research question

Treatment

The number and type of study designs reviewed

Three prospective randomised controlled trials were critically reviewed

Strength of evidence

Weak

Outcomes reported

Treatment with carprofen or meloxicam results in no significant difference in gastric lesion scoring, increased intestinal mucosal permeability or diminished small bowel absorptive capacity

Conclusion

There is insufficient evidence supporting preferential administration of carprofen or meloxicam to reduce gastrointestinal side effects

 

How to apply this evidence in practice

The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.

Knowledge Summaries are a resource to help reinforce or inform decision-making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care
The Importance of Proper Use of N95 Respirators by Health-Care Workers
Authors: Hoseini Azizi Tooba , Varasteh Saeideh , Esmaeili Maryam
Published: September 2020

The novel coronavirus causing the COVID-19 pandemic is spread by respiratory transmission through droplets and contact. The Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) recommend the use of personal protective equipment (PPE) including a gown, gloves, and a surgical mask or N95 respirator plus a face shield and/or goggles for health-care workers who are in direct contact with COVID-19 patients. A study in China by Wang found that health-care workers on the front line of disease treatment had inadequate training in the use of PPE, particularly for respiratory infectious diseases. Instruction in the proper use of N95 respirators, with an emphasis on performing user seal checks, as well as donning and doffing, is recommended for everyone caring for COVID-19 patients.
Languaging Network Learning: The Emergence of Connectivism in Architectonic Thought
Authors: Dennis Jeremy
Published: September 2020

As technological advancements and online education transform higher education, the achievement gap among students is widening rather than closing. Critics suggest that we need to reassess the promises of online education and the connectivism or network learning that is sometimes employed as its pedagogical underpinning. As scholars and practitioners struggle to define connectivism as a learning theory, many often exclude language as a feature in its conceptualization. This practice is at odds with architectonic thought, the philosophical tradition in which constructivist theories of learning are rooted. This article reveals the central role that language and texts play in architectonic thought and why they are inseparable from our understanding of knowledge and network learning. When we recognize language as a medium and model for reflection and criticality in the architectonic tradition, we are better positioned to use pedagogy and computer technology to transform online education and reorient our competing views of connectivism.
A Qualitative Inquiry of K–12 Teachers’ Experience with Open Educational Practices: Perceived Benefits and Barriers of Implementing Open Educational Resources
Authors: Tang Hengtao
Published: September 2020

Teachers in K–12 schools have shown an increasing desire for open educational resources (OER) to ensure all students can learn effectively. OER provide teachers with free access to open-licensed educational resources that they can retain, reuse, revise, remix, and redistribute for personalized instruction. Open educational practices (OEP) have been considered a pathway to reinforce the acceptance and readiness of K–12 teachers to use OER. This research thus showcases a qualitative study that investigates teachers’ experiences with OEP. This research explains K-12 teachers’ perceived benefits of implementing OER and also discusses their perceived barriers hindering OER usage in K–12 settings. The study also discusses the practical implications of integrating OER in K–12 curriculum.
FIRST REPORT OF STREBLOCERA MACROSCAPUS(RUTHE) (HYMENOPTERA BRACONIDAE EUPHORINAE) IN ITALY
Authors: LONI AUGUSTO , FORNACIARI MARCO , ROSSI ELISABETTA
Published: September 2020

A female ofStrebloceramacroscapus(Ruthe)(Hymenoptera Braconidae Euphorinae) was captured on a yellow sticky trap during a monitoring survey aimed atstudyinginsectbiodiversityinViareggio district (Lucca, Italy). This is the first report ofthis species inItaly.Biological information onS. macroscapusand itsparticular ecological niche are reviewed,and images of the specimenare presented. The importance of urban gardens and their proximity to the surrounding wild areas is also considered.
Knowledge of General Practitioner Doctors and Midwives Who Has and Has Not Attended Neonatal Resuscitation Course Has No Significant Difference
Authors: Lusida Vincent Geraldus Enoch , Semedi Bambang Puijo , Herwanto Bambang
Published: September 2020

Introduction: Infant death is most prominent in the neonatal period. The success of neonatal resuscitation practice has many contributing factors. One of which is the health workers’ knowledge of the Neonatal Resuscitation Program (NRP) algorithm. Therefore, it is necessary to conduct studies to evaluate the health workers’ knowledge of the Neonatal Resuscitation Program who are educated in neonatal resuscitation course and has taken part in Neonatal Life Support practice in primary health care (PHC)  Objective: This study aims to analyze the knowledge of general practitioners and midwives who has or has not attended in neonatal resuscitation course in Surabaya PHC Methods and Materials: this research is descriptive, cross-sectional research. All Basic Emergency Obstetric and Newborn Care (BEmONC) PHC in Surabaya which are Jagir PHC, Banyu Urip PHC, Medokan Ayu PHC, Tanah kali Kedinding PHC, Tanjungsari PHC, Balongsari PHC, Sememi PHC, Simomulyo PHC is included in this research from 2018 to 2019. A nine-item questionnaire referenced from The Textbook of Neonatal Resuscitation 7th Edition is given to ten respondents in each BEmONC PHC. Results and Discussion: from the total sample of 78 respondents, 32 (41,0%) receive a high score, 20 (25,7%) receive a middle score, and 26 (33,3%) receive a low score. The data shows that there is no significant score difference between respondents who has or has not participate in the NRP course (p=0,419). Conclusion:  There is no correlation between difference knowledge midwives and general practitioners who had and had not attended neonatal resuscitation training at basic emergency obstetric and newborn care in public health center Surabaya.
Effectivity Comparison of Ketamine and Morphine as Post-Operative Analgesic in Spinal Surgery
Authors: Fajarini Nenden Suliadiana , Rehatta Nancy Margarita , Utariani Arie
Published: September 2020

Introduction: Patients who undergo spinal procedure, experience the post-operative pain as the major problem. From the Visual Analog Scale (VAS), patients scale their pain around 8. An inadequate pain management could fasten the healing process and reduce patient life quality. Opioid group as the gold standard still inflicts several problems, such as respiratory depression. Moreover, the combination NSAID and opioid which used to suppress the side effect, still burden the healthcare cost. In a research of analgesic, through the discovery of N-Methyl D Aspartate receptor, researchers found an explanation of the ketamine effect in relieve chronic and intense pain which safer and cheaper. Method and Material: This research using single blind randomized control trial. Comparing 0.25mg/kg ketamine IV followed by ketamine 0,1mg/kg/h for the intervention group and 0.02mg/kg/h of morphine for the control group to manage the first 24 hours pain sensation. If patient VAS was more than 4, patient would get additional 0.5mg/kg ketamine (intervention group) and 25μg fentanyl (control group). Result and Discussion: From 17 patients each groups, the VAS values were better in control group rather than on intervention group. Low dose ketamine can’t be compared with morphine to manage post spinal procedure pain. There were no hemodynamic changes, respiratory rate depression, loss of consciousness and hallucination, nystagmus, vomiting and hyper salivation. Even though 11.8% of the subject were nausea. The morphine group tends to experience hemodynamic changes and loss of consciousness in the first 12 hours but still within normal range. In the control group, 47.1 % patients were having nausea in the first hour, but only 17.6% of them who actually vomited. Conclusion: The analgesic effect of morphine is higher than ketamine, but the amount effect of ketamine is lower than morphine so that ketamine is more effective and safer given in the room.
Fluid Resuscitation in Trauma
Authors: Abbas Kun Arifi
Published: September 2020

Introduction: Trauma is a problem faced everyday in the emergency room of the hospital where the researcher works. The degree of trauma from the mildest to life threatening can be found in sufferers. The cause of death in trauma sufferers is hypovolemic shock due to bleeding. The amount of blood loss volume from the patient can be estimated by looking at the clinical signs of the patient. Literature Review: In the condition of tissue hypoperfusion, it will cause a chain process which will eventually lead to cell death. Hypoperfusion causes anaerobic metabolism, lactic acidosis (coagulopathy, enzyme dysfunction), Na-K pump malfunction (cellular swelling and cell death), there is hypothermia (increase of oxygen demand, coagulopathy). Hypoperfusion will cause a vicious circle, in which processes that aggravate one another will occur. With the administration of fluids (crystalloid, colloid, transfusion) will improve the hypoperfusion that occurs in the body. Conclusion: The management of hypovolemic shock due to bleeding requires an understanding of the physiology and pathophysiology that occurs due to bleeding. To get maximum results and improve  outcome  from sufferers, it needs solid team work. Treatment can be different depending on the conditions, equipment and facilities of the hospital / emergency room as well as the policies of each place.
Comparing Alteration of MMSE (Mini-Mental State Examination) Scores as Cognitive Function Test in Geriatrics After General and Regional Anesthesia
Authors: Budianto Ferrie , Setiawan Philia , Hamzah Hamzah , Yulianti Erikavitri
Published: September 2020

Introduction: An alteration of cognitive function in geriatrics often occurred after a surgery procedure. To do a surgery, patients would go through the process with anesthesia, whether it is  general or regional anesthesia. We aimed to identify the effect of general and regional anesthesia in increasing the risk of alteration in cognitive function from geriatrics who underwent elective surgery followed by other risks. Material and Method: This observational analytic study has a total sample of 60 patients who aged 60 years or more, and half of the total sample underwent an elective surgery with general anesthesia, whereas the other half with regional anesthesia at Gedung Bedah Pusat Terpadu Dr. Soetomo General Hospital in a range of October – November 2016. The cognitive function of patients was assessed with MMSE which is done in approximately 10 – 15 minutes. Result and Discussion: There was a statistically significant correlation between age and both preoperative MMSE score also the alteration of MMSE score after 3 days in patients with regional anesthesia (P-value = 0.032; 0.044). Also, the correlation between educational status and preoperative MMSE score (P-value = 0.001). There was also a statistically significant difference in alteration of the MMSE score after 3 days between patients with general and regional anesthesia which went through the hypotension phase (P-value = 0.022; 0.003). We identified that both general and regional anesthesia could lead to alteration of MMSE score (P-value = 0.001; 0.02) and there was a statistically significant difference between both of them (P-value = 0.001). Conclusion: Both general and regional anesthesia could lower the cognitive function of geriatrics, especially general anesthesia which happened to have a higher risk to occur. Other factors such as age, educational status, and hemodynamic condition during surgery, had their impacts toward lowering cognitive function in geriatrics.
Pertanggungjawaban Pidana Terhadap Orang Tua yang Menjadikan Anak Kandung sebagai Pengemis dan Pengamen
Authors: Julianti Fanny
Published: September 2020

Anak adalah generasi penerus bangsa yang harus dilindungi oleh berbagai pihak yang dimulai dari lingkungan terkecil yaitu keluarga, masyarakat, pemerintah maupun negara. Kejahatan yang dilakukan kepada anak sebagai korban sering terjadi tetapi masyarakat tidak merespon kejahatan tersebut sehingga pada akhirnya kejahatan tersebut dianggap wajar terlebih dilakukan oleh Orang Tua dari anak tersebut. Tindak pidana yang sering dilakukan oleh Orang Tua terhadap anak kandung yaitu dengan sengaja menelantarkan kebutuhan primer maupun sekunder dari anak tersebut. Pada dasarnya penelantaran terhadap anak termasuk dalam kekerasan secara sosial yang menimbulkan luka secara psikis maupun fisik dan tentunya sangat membekas di dalam ingatan anak yang menjadi korban penelantaran tersebut. Penelantaran terhadap anak tersebut adalah awalan untuk melakukan eksploitasi secara ekonomi dengan modus operandi menjadikan anak kandung sebagai pengemis dan pengamen demi memenuhi kebutuhan hidup keluarga yang seharusnya bukan sebagai tanggung jawab seorang anak dalam keluarga.Pelaku yang menjadikan anak sebagai pengemis dan pengamen adalah sekup terkecil dalam masyarakat yaitu Orang Tua. Pertanggungjawaban pidana bagi orang yang dengan sengaja mengeksploitasi anak secara ekonomi dengan modus operandi menjadikan anak tersebut sebagai pengemis dan pengamen diatur dalam Undang-Undang Nomor 35 Tahun 2014 Tentang Perubahan atas Undang-Undang Nomor 23 Tahun 2002 tentang Perlindungan Anak.