bluuebunny/crossref_metadata_2025 huggingface dataset:
Does causal dynamics imply local interactions?
Authors: Zimborás Zoltán , Farrelly Terry , Farkas Szilárd , Masanes Lluis
Published: June 2022

We consider quantum systems with causal dynamics in discrete spacetimes, also known as quantum cellular automata (QCA). Due to time-discreteness this type of dynamics is not characterized by a Hamiltonian but by a one-time-step unitary. This can be written as the exponential of a Hamiltonian but in a highly non-unique way. We ask if any of the Hamiltonians generating a QCA unitary is local in some sense, and we obtain two very different answers. On one hand, we present an example of QCA for which all generating Hamiltonians are fully non-local, in the sense that interactions do not decay with the distance. We expect this result to have relevant consequences for the classification of topological phases in Floquet systems, given that this relies on the effective Hamiltonian.

On the other hand, we show that all one-dimensional quasi-free fermionic QCAs have quasi-local generating Hamiltonians, with interactions decaying exponentially in the massive case and algebraically in the critical case. We also prove that some integrable systems do not have local, quasi-local nor low-weight constants of motion; a result that challenges the standard definition of integrability.
PREVALENCE OF CHILDHOOD BRONCHIAL ASTHMA AMONG SCHOOL GOING CHILDREN IN KOMARAPALAYAM, NAMMAKAL DISTRICT,TAMIL NADU,INDIA.
Authors: SEN SNEHA , ELSA VARUGHESE PRAISY , MOHAMMED ARSHAD K.K  , N. VENKATESWARAMURTHY  , R. SAMBATHKUMAR
Published: June 2022

Childhood asthma is the common chronic illness among school going children. It was a syndrome characterized by airflow obstruction that differs strikingly. There were very few school based studies on the prevalence of asthma in Indian children. We aimed to estimate the prevalence of asthma in children between 12 -15 years of age group at Komarapalayam, Namakkal District, Tamil Nadu on the basis of Intenational Study Of Asthma and Allergies in Childhood (ISAAC) tool. A total of 991 students were selected from three schools of Komarapalayam, Namakkal district for the period of May 2018 to October 2018. The data was collected by using the ISSAC questionnaire. The results obtained were significant for the different age group of students. Out of 991 students, the overall prevalence of childhood asthma was found to be 10.3%. In this study, the total number of diagnosed students was 102 and out of such 102 students, early diagnosed was found to be 48 and newly diagnosed was 54. The higher prevalence was seen in 12 and 15 years of aged category students when compared with the other two. Our study suggested that asthma can be seen more in this study population. So, these exposures can be prevented by giving proper awareness programs for both children and parents, proper education and screening of asthma in school for early diagnosis and better asthma management
RESPON KERAJAAN MALAYSIA TERHADAP PEMERDAGANGAN MANUSIA, 2010-2015
Authors: Arnakim Lili Yulyadi , Zulhadis Muhammad
Published: June 2022

This article aims at discussing the Malaysian government’s response towards human traffings in Malaysia from 2010-2015. The study was based on qualitative method by referring various data. The findings show that human traffing in Malaysia has been emeanated from various factors that include individual victims, themselves, or external factors. This human trafficking has to some extent, led to the emergence of negative perception, and tarnished the image of the country. As such the Malaysian government has introduced policy blueprints for combating the human trafficking. This blueprint is important to examine how serious is the government in combating the crossedcountryhuman trafficking. Law enforcement which has been carried out by the government agencies is one of the responses that was provided by the Government. With the strong collaboration from Anti trafficking council and anti migrants muggling (MAPO), enforcement agencies which have been perceived as commited and mutually assiting in the case of human trafficking issues. The government was severely critized by the USA in the human trafficking issues for being unable to exercise the standard requirements which was agreed among the USA. However due to enhancement and commited cooperation with Non-Governmnet Organizations, Malaysian government has attempted to provide the protection for vistims as coicided with meeting the USA reqirement and refine the better tier position of Malaysiain the world.
A CRITICAL DISCOURSE OF THE IMPACT OF THE TRANS-SAHARAN TRADE AND THE 19TH-CENTURY JIHAD ON THE HISTORY OF AKWANGA DIVISION, NIGERIA
Authors: Dogara Ja'afaru Yusuf , Abd Hamid Hamidin
Published: June 2022

The spread of Islam from East and North Africa across the Sahara Desert to Nigeria is ascribed to certain socio-economic and political factors. The development of Islam in the geopolitical zone of central Nigeria faced notable challenges due to the heterogeneity of the ethnic and cultural identity of its local population, the inability of the Muslim Arab merchants to establish trade relations with the area, and the politicization of jihad which was met with fierce resistance. This made it impossible to effectively propagate the Islamic teachings among the local population in central Nigeria. This study will explore the history and culture of the Akwanga Division before the advent of Islam and identify the challenges faced by the movement. Emphasis will be laid on the role of the trans-Saharan trade, the jihad of Usman Dan Fodio, and their impact on the socio-economic life of the area. Also examined will be the factors responsible for delaying the spread of Islam in central Nigeria. The aims and objectives of this research work will be achieved by using secondary data such as published articles in reputable academic journals, edited works, internet sources, and books.
PENGASASAN DAN PERANAN AGENSI PENGUATKUASAAN MARITIM MALAYSIA, 2004-2014
Authors: Mohd Rus Ahmad Kamal Ariffin , Abdul Rahman Zulkarnain , Mustazar Muhammad Hidayatur Rahman
Published: June 2022

This article examines the Malaysian Maritime Enforcement Agency (MMEA) in the context of its establishment and role to patrol and protect the Malaysian maritime zones. The discussion focuses on its establishment, its main roles, and the challenges faced. Qualitative analysis is used to study data obtained from both primary and secondary sources. Among the primary sources used include the acts related to national maritime zones, the MMEA Annual Reports, the Malaysian International Trade and Industry Reports, Malaysian Transportation Statistics, Parliamentary Hansards, and local periodicals. Based on the sources used, the study found that the lucrative importance of our national maritime zones compelled the government to create a new specific agency to patrol and protect our waters. The MMEA operations officially began on 30 November 2005. Although this agency is responsible for national security, its staff scheme is categorised as the public sector, in contrast to the schemes of service for the Marine Police and the Malaysian Royal Navy (TLDM). The largest role and challenge of the MMEA in patrolling national waters involve both supervision and coordination. Although equipped with radar surveillance system, our vast maritime zones naturally tempt activities of piracy, smuggling, encroachments by foreign fishermen, and movements by illegal immigrants. The vague legal provisions meant other enforcement agencies are seen as operating within the ambit of MMEA portfolio, causing problems of ineffectiveness and hindering the MMEA’s role of coordination.
KUWAITI WORKERS AND WESTERN OIL COMPANIES 1946-1960
Authors: Juraid Ayed Ateeq
Published: June 2022

Kuwaiti oil was very important for oil companies of colonial powers such as the Anglo-Persian Oil Company, APOC, and Gulf Oil Company. Those two companies managed to acquire oil concession inside Kuwait. Although they achieved huge financial profits led to welfare and happiness of American and British peoples, they, however, broke the terms of the concession agreement regarding Kuwaiti workers rights by not providing jobs, training, qualifying, high position and other rights. In return, Kuwait witnessed a successful labor movement led to having workers’ rights. Moreover, that movement had a potential role in the decision of nationalization of foreign oil companies later in 1975. In light of the above, this study aims at highlighting the most important companies that had oil concessions in Kuwait. Also, it seeks to identify their real policies toward Kuwait and its workers. In addition, the finding tries to show the Kuwaiti workers response on the companies which exhausted Kuwait’s resources and depraved Kuwaitis from their normal rights. As far as the method followed by the study, nature of the research requires applying the suitable analytical approach. That is, via the references and sources used in study, the linked points with the subject are being specified, analyzed and objectively criticized in order to show the injustice that had taken place from colonial oil companies upon Kuwaiti workers.
THE ‘CYPRUS QUESTION’ AND BRITAIN’S DECISION TO LEAVE TURKEY AND GREECE OUTSIDE NATO, 1948-1949
Authors: Hussain Norasmahani
Published: June 2022

The North Atlantic Treaty Organisation (NATO) is an intergovernmental military alliance of unusual geographical membership that was signed on 4 April 1949 in Washington D.C. Twelve countries famously became founding members, but Turkey and Greece were surprisingly not included. In point of fact, these two Mediterranean countries were arguably victims that suffered from the ‘aggression’ of the Soviet Union in the early post-Second World War years and had some strong reasons for being included in NATO. The literature usually focuses on the geographical area of Turkey and Greece and a Mediterranean Pact in explaining why Britain refused to invite these countries to join NATO during its formation years. However, when placing more attention to the perspective of British Foreign Secretary Ernest Bevin and his Foreign Office regarding this rejection issue, the ‘Cyprus question’, which refers to a major dispute between Greece and Turkey over Cyprus, also influenced them in tightening Britain’s decision to leave Turkey and Greece outside NATO. This study is using qualitative method like archieval data. The finding of this study shows that British documentary analysis illuminates the degree of influence of the problem of Cyprus on British considerations of western security. In particular, this paper offers analysis of British Foreign Office objections to the admission of Turkey and Greece to NATO before NATO was successfully established. Previous researchers have largely drawn attention to Britain’s general views on the structure and membership of NATO, and on Britain as a major instigator of the alliance. This paper, however, will discuss the ‘objection issue’ towards Turkey and Greece from the point of view of Britain, particularly from the perspective of the ‘Cyprus question’.
Cierre anticipado o temporal de minas: Pautas para un modelo contextualizado en el departamento del Cesar, Colombia.
Authors: Muñoz Lopez Jhon Marlon
Published: June 2022

El cierre y postcierre de minas es un tema relevante del que poco se habla en el marco de las actividades mineras en todas sus dimensiones. Para el caso colombiano y particularmente en el departamento del Cesar cobra particular importancia analizar esta situación, pues en la actualidad este departamento es uno de los de mayor actividad minera en Colombia. El objetivo de este artículo es revisar y reflexionar de manera conceptual sobre dinámicas de cierre y postcierre anticipado o temporal de minas con miras a establecer pautas para un modelo que involucre de manera sistemática condiciones ambientales, sociales, financieras y técnicas de manera articulada y permanente.
Intro to Social Media
Authors: Lawson Cheryl
Published: June 2022

This book is aimed at managers, business owners, marketing managers, and aspiring social media marketing interns and managers. I will assume that however accomplished in your own field - baker, developer, teacher and that even as successful business owners, you approach the topic of social media marketing as a beginner. Even if you are an avid personal user of social networks, we will treat this book as a guided tour of social media for marketing purposes.
Madurez y autores de la gestión del conocimiento
Authors: Castellanos Narciso José Ever , Vega Guerrero Juan Camilo
Published: June 2022

El objetivo de este capítulo es dar a conocer al lector los diferentes niveles de madurez que se encuentran en las organizaciones y que muchas veces se desconocen. Para el logro de este objetivo, se indagó en los principales autores que han aportado su conocimiento en el tema, al igual que aquellos que con sus modelos han demostrado que las organizaciones, según su tamaño, pasan por diferentes niveles de madurez. Entre ellos se tienen las categorías de participantes sin conciencia, participantes con conciencia, conocimiento estructurado, pre-óptimo y óptimo.
Diversidad cognitiva en equipos de alta dirección y la organización ambidiestra como aporte a la gestión del conocimiento: un marco conceptual
Authors: Castellanos Narciso José Ever , Mora Pabón Ricardo
Published: June 2022

Los procesos cognitivos de los equipos de alta dirección facilitan la ambidiestralidad y la gestión del conocimiento En este estudio se explora la composición de los equipos de alta dirección (EAD), en particular, la heterogeneidad del EAD basada en la diversidad cognitiva sobre la organización ambidiestra. El propósito fue conocer el foco de atención que equilibra la exploración y la explotación.
Vietnamese teachers’ attitudes toward online professional development programs
Authors: Van Dao Thi Hong , Thi Ha Hoang Quoc , Khang Nguyen Duy
Published: June 2022

In addition to the massive deployment of online learning among students worldwide, virtual training has also become a necessity to ensure the demand of teacher professional development. Exploring teachers’ attitudes toward online training programs helps educational stakeholders in understanding their expectations toward professional training modes, which positively contribute to boosting the effectiveness of career development programs. The present study sheds some light on Vietnamese English teachers’ attitudes toward online professional development programs. Twenty-five EFL teachers in Can Tho city Vietname took part in the research by providing answers to the questionnaire delivered using Google Form application; ten of them volunteered to attend further interview sections. The results of pair sample t-tests show that the English teachers preferred face-to-face to online training programs. In addition, the qualitative findings further revealed that they had no offense to online training mode, yet deny its sole implementation for all future professional development activities. Especially, most teachers approved the practice of online training in the context of the COVID-19 pandemic. Moreover, some of them started to acknowledge a blended teacher training program as they are relying in its affordances and accessibility. Considering the crucial role of development programs for teachers, the findings of this study contribute to providing input enhancement for teacher professional training stakeholders in Vietnam.
Refute of Goldbach Conjecture
Authors: Janardana Dhruva
Published: June 2022

This work is about the goldbach conjecture . Here i have attempted to
disprove it using different methods, just to brief it it involves
ramanujan’s derivation of riemanns’s zeta function. I would request you
to kindly review and let me know the feedback. Thank you
Interplay between hydrogen and chalcogen bond in cysteine
Authors: Carugo Oliviero
Published: June 2022

Protein structures are stabilized by several types of chemical
interactions between amino acids, which can compete with each other.
This is the case of chalcogen and hydrogen bonds formed by the thiol
group of cysteine, which can form three hydrogen bonds with one hydrogen
acceptor and two hydrogen donors and a chalcogen bond with a nucleophile
along the extension of the C-S bond. A survey of the Protein Data Bank
shows that hydrogen bonds are about 40-50 more common than chalcogen
bonds, suggesting that they are stronger and, consequently, prevail,
though not always. It is also observed that frequently a thiol group
that forms a chalcogen bond is also involved, as a hydrogen donor, in a
hydrogen bond.
Fault Detection and Classification using Deep Learning Method and Neuro-Fuzzy Algorithm in a Smart Distribution Grid
Authors: Foba Vinny , Boum Alexandre , Mbey Camille , Yem Felix
Published: June 2022

Fault detection is crucial in smart grid control and monitoring
operations. The use of smart meters leads to appearance of a large
amount of digital data whose conventional and chronological techniques
are not efficient enough for processing and decision-making. In this
paper, a novel data analysis model based on deep learning and
neuro-fuzzy algorithm is proposed for detection and classification of
faults in a smart grid. First, the Long Short Term Memory (LSTM) based
deep learning model is applied for training the data samples extracted
from the smart meters. Then, the Adaptive Neuro Fuzzy Inference System
(ANFIS) is implemented for fault detection and classification from the
trained data. With this intelligent method proposed, single-phase,
two-phase and three-phase faults can be identified using a restricted
amount of data. To verify the effectiveness of our methodology, an
intelligent model of the IEEE 13-node network is used. The results
indicate that the combined ANFIS-LSTM deep learning model outperforms
existing machine learning methods in the literature in terms of accuracy
for fault detection and classification.
An Atypical Presentation of Bilateral Pulmonary Embolism with Abdominal Pain: A Case Report and literature review
Authors: Musa muzamil , Abdalla ELMustafa , Alamin Mohammed , Mustafa Gihan , Osman Ahmed Elmudathir , Karrar Mohanned , fadul abdalla
Published: June 2022

Pulmonary embolism is a potentially fatal condition that encountered in
practice and mandates prompt identification and management. If left
untreated, a delay in diagnosis can be catastrophic for the patient and
carry a significant risk of death.
Risk factors for recurrent respiratory tract infections or acute respiratory failure in children with spinal muscular atrophy
Authors: Guo Wenhui , Meng Linghui , Cao Ling
Published: June 2022

Introduction: Assessment of and intervention for
sleep-disordered breathing and malnutrition are related to respiratory
management for preventing recurrent respiratory tract infections (RRTIs)
and acute respiratory failure (ARF) in children with spinal muscular
atrophy (SMA). However, the specific standard has not been clarified.
Purpose: The study aimed to obtain the risk factors and the
predictive index for RRTIs and/or ARF in children with SMA.
Methods: In this retrospective study, the differences in
clinical characteristics in patients with or without RRTIs and ARF were
compared, and binary logistic regression analysis was carried out. The
best cutoff points of the positive predictive index were obtained.
Results: Type 1 (OR = 4.12, 95% CI 1.30-13.07, P =.016) and
apnea hypopnea index (AHI) (OR = 1.14, 95% CI 1.05-1.24, P =.001) were
risk factors, while body mass index z score (BMIz) (OR = 0.68, 95% CI
0.49-0.94, P =.018) and mean pulse oxygen saturation (MSpO
) (OR = 0.67, 95% CI 0.50-0.91, P =.010) were
protective factors. The sensitivity and specificity of the standard of
MSpO < 96% and AHI > 10
events/h or BMIz < -1 with the occurrence of RRTIs and/or ARF
were 0.513 and 0.957, respectively. Conclusion: SMA Type 1,
BMIz, AHI and MSpO should be used to estimate the risk
for RRTI or ARF in children with SMA. MSpO <
96%, and AHI > 10 events/h or BMIz < -1 should
be used as the intervention standard.
Rare triad of fractures in the upper limb. Simultaneous fractures of the distal radius, with the radial head and the ulna styloid.
Authors: Elgassim Mohamed , Abulhaya Ammar , Abdelrahman Amro , Elgassim Moayad , Kumar Thirumoothy
Published: June 2022

A rare combination of ipsilateral fracture of proximal and distal ends
of the radius associated with ulna styloid fracture due to a fall with
outstretched hands. Appropriate management for such cases depends on the
characteristics of the injury, The treatment should aim to preserve the
radial head to avoid complications.
Biventricular cardiac metastasis from vulvar squamous cell carcinoma
Authors:   Oncology Institute ", Spînu Ștefan ,   Prof. Dr. Ion Chiricuţă",   , Medical Oncology Department, Cluj-Napoca, Romania, Sur Daniel ,   Oncology Institute "Prof. Dr. Ion Chiricuţă", Medical Oncology Department, Cluj-Napoca, Romania, Pârv Andreea ,   Heart Institute “Niculae Stăncioiu” Cluj-Napoca, Cluj-Napoca, Romania
Published: June 2022

Vulvar cancers make up just 3% to 5% of all gynecological cancers, and they are most typically found in postmenopausal women. Vulvar cancer distant metastases are uncommon and usually arise late. Only six cases of vulvar cancer metastasizing to the heart have been reported in the literature, and none of them included both the left and right ventricles. We describe the case of a 68-year-old patient diagnosed with vulvar cancer arising from lichen sclerosus, initially localized, treated with chemotherapy, surgery, and radiation therapy. Less than two months after the end of the treatment sequence, the patient returned to our clinic with bone pain. Imaging investigations have shown multiple disseminated metastases, but not in the heart at that moment. Chemotherapy was initiated, and after two cycles, the patient developed an arrhythmia (atrial fibrillation with rapid ventricular rate), which was later determined to be caused by cardiac metastases discovered by echocardiography and computed tomography. Vulvar cancer metastatic to the heart represents a rare clinical condition, requiring multidisciplinary care. The case's uniqueness is the biventricular metastasis, which resulted in STEMI despite angiographically normal epicardial coronary arteries.
Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs: does age matter?
Authors:   Department of Allergology “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Ali Selda , Udrea Ruxandra ,   Department of Allergy and Clinical Immunology, “Dr. Carol Davila” Nephrology Clinical Hospital, Bucharest, Romania, Boustani Rama ,   Department of Allergy and Clinical Immunology, “Dr. Carol Davila” Nephrology Clinical Hospital, Bucharest, Romania
Published: June 2022

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are reported to be the leading cause of drug hypersensitivity reactions. The aim of this study was to characterize a cohort of patients with NSAID hypersensitivity and establish if there are any differences between two groups of adult patients, under 55 years old and over 55 years old, and identify safe alternative options. Methods: Patients with NSAID hypersensitivity who were referred to a single tertiary Allergy center from January 2019 to December 2021 were included. Clinical information was obtained from a review of medical records. Results: A total of 135 patients with a history of NSAID-induced hypersensitivity reactions were included, 80 patients under 55 years old and 55 patients older than 55. Most of the patients enrolled were female (80.74%) and the mean age was 50.21 years, ranging from 18 to 78 years old. The time interval between the first reaction and the allergy work-up was longer in the older group (average timeframe 6.87 years) than in the younger group (average timeframe 3.77 years). The main culprit was metamizole in both groups. An oral provocation test to paracetamol was performed in most of the patients who tolerated the intake of 1000 mg, except for 2 patients who developed angioedema. Conclusion: Angioedema was the most encountered symptom in our population. Age does not influence the allergy work-up of patients with a history of NSAID-induced hypersensitivity reactions. The drug provocation challenge remains the gold standard for finding a suitable alternative in patients with NSAID-induced hypersensitivity.
EXPLORATION OF VIRTUAL INCUBATORS AND DEVELOPMENT OF INCUBATOR SERVICES FOR DIGITAL ENTREPRENEURSHIP: RECEIVING ENTREPRENEURIAL SUPPORT FROM ANYWHERE IN THE WORLD.
Authors:   Lagos State Polythetic Ikorodu, Lagos1, Sarumi,  (PhD) Jerry Abayomi ,   Augustine University Ilara-Epe, Lagos State2., Ogunjimi L.O.A
Published: June 2022

Entrepreneurship is frequently linked together with aspects of economic growth and development. In the last 40 years, an increasing number of incubators and service providers have been created to stimulate entrepreneurship and innovation. However, in the increasingly globalized and digitalized world, few virtual and digital initiatives have successfully been studied to encourage and facilitate entrepreneurship. This study aims to understand further how digital and virtual products and services can aid entrepreneurs in venture creation and potentially add to an updated and broader understanding of the potential in a virtual incubator program. By looking at three categories of entrepreneurial support actors, traditional public incubators, private incubators, and digital service providers. 14 semi-structured interviews were conducted to gain more in-depth knowledge of how they operate. More specifically, this study is conducted with actors that share the vision to assist startup in their initial phase and create a deeper understanding of what the incubator offers to startups and the possibility to adapt and improve their process using digital tools and external partnerships. Results indicate that the use of digital tools is varied. Incubators are leaning towards relying more on social media for reaching potential entrepreneurs and ideas, and further that a factor of validating every aspect of the startup is essential to promote success. The incubator mainly acts as a mediator of network, funding, coaching, and finding talents has during the COVID-19 pandemic moved most of their activities from physical to online. The issue of trust-building is, however, still prominent, and the incubators are looking for ways and tools to improve on this issue. Implications of this study have the potential to lower barriers to entrepreneurship, where entrepreneurial support becomes less dependent on their local ecosystem and geographical factors. Future research is encouraged to classify virtual incubators and a further look at specific cases and pursuit more longitudinal studies to fully understand the potential effects and implications. This study contributes to the field of incubators and entrepreneurial support and the ongoing digital paradigm shift. Keywords: Business Incubator, Virtual Incubator, Entrepreneurial Support, Digital Entrepreneurship, Startup
Mechanistic insights into the heterogeneity of glucose response classes in youths with obesity: a latent class trajectory approach
Authors: Tricò Domenico , McCollum Sarah , Samuels Stephanie , Santoro Nicola , Galderisi Alfonso , Groop Leif , Caprio Sonia , Shabanova Veronika
Published: June 2022

  

Objective. In a large multiethnic cohort of youths with obesity, we analyzed pathophysiological and genetic mechanisms underlying variations in plasma glucose responses to an oral glucose tolerance test (180min-OGTT).

Research Design and Methods. Latent class trajectory analysis was used to identify different glucose response profiles to 9-point, 180min-OGTT in 2,378 participants in the “Yale Pathogenesis of youth-onset T2D” study, of whom 1,190 had available TCF7L2 genotyping and 358 had multiple OGTTs over a 5-year follow-up. Insulin sensitivity, clearance and β-cell function were estimated by C-peptide modeling. 

Results. Four latent classes were identified and numbered from 1 to 4 based on increasing areas under the glucose curves. Subjects in class 3 and 4 had the worst metabolic and genetic risk profiles, featuring impaired insulin sensitivity, clearance, and β-cell function. Model-predicted probability to be classified as class 1 and 4 increased across ages, while insulin sensitivity and clearance showed transient reductions and β-cell function progressively declined. Insulin sensitivity was the strongest determinant of class assignment at enrolment and of the longitudinal change from class 1 and 2 to higher classes. Transitions between class 3 and 4 were explained only by changes in β-cell glucose sensitivity. 

Conclusions. We identified four glucose response classes in youths with obesity with different genetic risk profiles and progressive impairment in insulin kinetics and action. Insulin sensitivity was the main determinant in the transition between lower and higher glucose classes across ages. In contrast, transitions between the two worst glucose classes were only driven by β-cell glucose sensitivity.  
Razão pública e a abordagem pragmatista da pluralidade
Authors: Zanette José Luiz , Melo Caique Marra de , Saran Lucas Antonio
Published: June 2022

Este artigo tem por objetivo refletir sobre as noções de pluralismo e multiculturalismo à luz do conceito de razão pública na contemporaneidade. Considera os progressos kantianos condizentes aos seres humanos enquanto meio e fim do processo ordenado e ideal de estabelecimento da correção normativa ética pela mediação racional a fim de propor, de modo central, a partir de Charles S. Peirce e Chantal Mouffe, por um lado, veredas de renovação da relação lógica entre o ideal e o empírico, de modo a não reclamar para a ética a condição de fundamento último, considerado o falibilismo peirciano, bem como a contingencialidade dos discursos, pressupondo, assim, uma permanente relação semiótica em processo de aceitabilidade racional; e, por outro lado, a negação de formas estritas de universalidade, propondo a dessacralização do consenso baseada numa apologia do retorno às batalhas hegemônicas, resguardados os riscos dogmáticos inerentes a um nominalismo carente de uma epistemologia falibilista.
Reflexões sobre a arte
Authors: Haubert Laura Elizia
Published: June 2022

Tradução do artigo: Emerson, Ralph Waldo. Thoughts on Art. In: The Dial, vol.1, n.3, p. 367-379, 1841.
A querela interpretativa da teoria de abstração de John Locke e o olhar de Charles S. Peirce sobre o anti-abstracionismo de George Berkeley
Authors: Melo Caique Marra
Published: June 2022

O presente artigo tem por objetivo apresentar, dada a enunciação de Charles S. Peirce acerca do caráter oportuno da refutação de George Berkeley à suposta teoria de abstração defendida por John Locke, a querela interpretativa de comentadores da obra lockiana sobre o modo através do qual o filósofo britânico compreende a universalidade das ideias, seguindo, centralmente, um esquema de subdivisão aceito por estudiosos lockianos – a saber, teoria intrísenca de abstração e teoria extrínseca de abstração –, para assim, num segundo momento, evidenciar o arbítrio berkeleyano a redundar numa reductio ad absurdum acerca da perspectiva de Locke sobre a capacidade de abstração humana, ratificando, segundo o pai do pragmatismo, o caráter astuto encontrado no movimento, por fim exposto, de refutação – autodenominado “golpe de misericórdia” – de George Berkeley.
Surrealismo, expressionismo e arte proletária em Mário Pedrosa (1925-1933)
Authors: Mari Marcelo
Published: June 2022

A obra de juventude de Mário Pedrosa ainda hoje é pouco conhecida do público universitário. Isso se deve à falta de publicações que reúnam e que discutam a importância da produção intelectual de Pedrosa nesse período. O presente artigo reconstitui sua trajetória intelectual, entre os anos de 1925 e 1933, com ênfase no debate cultural travado sobre a arte de vanguarda e seu impacto no Brasil. Naqueles anos, Pedrosa estava interessado em deslindar a relação entre arte de vanguarda e política de vanguarda.
Incidência de cefaleia após anestesia subaracnoídea em uma maternidade filantrópica
Authors: Cecilio Gustavo Moreno , Sleiman Luma Garcia , Ferez David
Published: June 2022

Introdução: Uma das complicações da anestesia subaracnóidea é a cefaleia pós-punção dural, ocorrendo em aproximadamente 1,5% dos casos, com característica debilitante representando causa primária de morbidade e aumento do tempo de permanência hospitalar. Objetivo: Avaliar a incidência de cefaleia pós punção-dural em pacientes obstétricas submetidas a cesariana em uma instituição de saúde terciária. Método: Trata-se de um estudo observacional, analítico, realizado em um hospital terciário, com uma amostra de 100 pacientes (três casos). Utilizaram-se formulários com duas partes: a primeira para caracterização das participantes e a segunda para coletar dados referentes à presença de cefaleia pós-punção dural. O desfecho primário foi apresentado pela incidência com intervalos de confiança de 95% (IC95%). Os casos encontrados foram descritos após a análise dos resultados. Resultados: O resultado foi dividido em: variáveis epidemiológicas; variáveis relacionadas à gestação, ao trabalho de parto e ao parto; variáveis relacionadas às comorbidades das pacientes e à cefaleia pós-punção dural. Sobre o procedimento da anestesia subaracnóidea, o tipo de agulha utilizado foi informado em 69% dos registros, sendo utilizado apenas o modelo bisel cortante. A incidência de cefaleia pós-anestesia subaracnóidea foi de 3%, podendo variar de 0–6%. Das três puérperas que apresentaram a cefaleia pós-punção dural, nenhuma necessitou de tampão sanguíneo peridural. Conclusões: A incidência de cefaleia pós-punção dural, na instituição de estudo, foi superior à descrita na literatura, possivelmente associada ao uso exclusivo de agulha de punção dural com bisel cortante. Estatisticamente, as características epidemiológicas e os fatores de risco das pacientes com cefaleia pós-punção dural foram ...
Cirurgia com neurofisiologia intraoperatória para ressecção microcirúrgica dos gliomas de alto grau de área motora em pacientes desacordados com anestesia geral (asleep)
Authors: Sidani Nadjila Gabriela Santana , Brock Íris Cristina , Aguiar Paulo Henrique Pires de
Published: June 2022

Introdução: Os gliomas difusos são tumores primários do sistema nervoso central, que, apesar da melhoria das técnicas para os tratamentos, continuam como desafios para a medicina dados os seus padrões dinâmicos de crescimento e comportamento. Atualmente, uma das alternativas de tratamento estudadas pauta-se na porcentagem da ressecção e na área eloquente envolvida. A porcentagem de ressecção é um importante fator prognóstico independente que define a sobrevida nos pacientes. Objetivo: Mostrar a casuística da abordagem cirúrgica asleep de tumores em área motora. Método: Estudo retrospectivo em pacientes submetidos a ressecção cirúrgica asleep de gliomas de alto grau, com monitoração eletrofisiológica intraoperatória somatossensitivo motora, com ressecção dos tipos parcial, subtotal e total, por meio de craniotomia e microcirurgia. A análise dos resultados baseou-se na avaliação da evolução pós-operatória pela Escala de Karnofsky. Resultados: Na amostra verificada, pode-se aventar que a técnica operatória asleep é segura na abordagem nas áreas motoras. Todos os pacientes que apresentaram déficits evoluíram para óbito em razão do caráter agressivo da doença. Conclusão: Pode-se concluir que a técnica operatória asleep é segura quanto à abordagem nas áreas motoras, com complicação intraoperatória extremamente baixa e evolução prognóstica a depender da agressividade inicial do tumor.
Avaliação dos níveis de atendimento e controle de crianças com diagnóstico de asma
Authors: Santos Victoria Machado , Melo Kaio Souza de , Rocha José Inácio Pereira da
Published: June 2022

Introdução: A asma é doença inflamatória crônica associada à hiper-responsividade das vias aéreas inferiores e multifatorial. Estima-se que, no Brasil, existam 20 milhões de asmáticos, e a baixa resolutividade da atenção primária, a ausência de protocolos de regulação dos encaminhamentos e a dificuldade na contratação de profissionais médicos levam ao aumento da referência aos serviços de atenção especializada. Objetivos: Avaliar as crianças atendidas num serviço de atenção referenciado. Métodos: No Ambulatório de Pneumologia Infantil do Conjunto Hospitalar de Sorocaba (CHS), foram aplicados questionários que abordaram dados pessoais básicos e perguntas relacionadas à asma do paciente. Os resultados foram analisados pelo método estatístico do χ2. Resultados: A porcentagem de crianças que tiveram até três crises tratadas em casa foi maior do que a das que tiveram mais de três crises. Não se demonstrou qualquer relação entre a presença de pediatra no bairro ou na cidade de origem e o controle da asma. O controle também não se relaciona com o número de consultas no Ambulatório de Pneumologia Infantil do CHS. Conclusão: Doenças crônicas impactam significativamente a saúde do indivíduo e a saúde pública, e a implementação bem-sucedida de políticas de saúde leva à expansão do acesso à atenção primária em saúde e à redução da mortalidade. Deve-se então investir em melhorias para o acesso à atenção básica, considerando-se que o controle permanece aquém mesmo em um centro secundário de saúde, e que a comunicação entre as duas esferas, se fluida, pode garantir resultados mais satisfatórios.
Perfil clínico e demanda de pacientes de um ambulatório de genética do sul fluminense
Authors: Almeida Thiago Tadeu Santos de , Dias Lorena Araújo Silva , Souza Caio Meirelles de , Gambarato Bruno Chaboli , Utagawa Claudia Yamada
Published: June 2022

Objetivos: Analisar e compreender as demandas e o perfil dos usuários atendidos em um ambulatório de genética do sul fluminense, buscando o aprimoramento dos atendimentos. Método: Trata-se de um estudo retrospectivo que avaliou os prontuários de 119 pacientes atendidos em 2018. Resultados: Verificou-se que 90% dos encaminhamentos para avaliação genética foram realizados por médicos de diversas especialidades, com predomínio dos pediatras (19,3%). Dos pacientes, 51,3% eram oriundos do município de Volta Redonda (RJ) e o restante de outros 14 municípios do Rio de Janeiro e de Minas Gerais. A maioria dos pacientes (93,3%) era casos índice, e os demais buscavam aconselhamento genético. Nos casos índice, não houve diferença de sexo, e a faixa etária predominante foi entre 5 e 9 anos. Foram diagnosticadas mais de 50 doenças genéticas, sendo as mais frequentes a síndrome de Down, a síndrome de Turner e a neurofibromatose. Conclusão: As doenças raras apresentam diversas causas, sendo 80% delas de origem genética. Para atender pacientes com essa condição, é preciso ter serviços especializados em genética médica. A maioria desses serviços concentra-se nas regiões Sudeste e Sul, entre eles o ambulatório de genética clínica vinculado à Faculdade de Medicina do Centro Universitário de Volta Redonda, em Volta Redonda. Os dados avaliados auxiliam na compreensão do perfil dos pacientes e nas demandas do sistema de saúde da região, possibilitando planejar a capacitação de profissionais para a identificação de pacientes com prováveis doenças genéticas e organizar o fluxo de encaminhamento para o serviço, incorporando uma logística mais eficaz.
Experiência, narrativa, história
Authors: Papageorgiou Ulysses Barros
Published: June 2022

Através de uma leitura comparada entre Dostoiévski e Leskov evidencia-se a compreensão estética e política de Walter Benjamin, cujo pensamento se encontra pungente em aspectos da contemporaneidade, tal como o fenomeno poético do Slam.
Amend, Replace and Cut Off
Authors: Figueiredo Jr. Eberval Gadelha , Dias Antônio Gonçalves
Published: June 2022

The prominent Brazilian romantic author Antônio Gonçalves Dias (1823-1864) visited Europe from 1854 to 1858, on an official academic mission on behalf of the Brazilian government and emperor Pedro II, to whom this letter is addressed. The emperor was responsible for gathering a group of intellectuals in the Brazilian Historical Geographic Institute. Gonçalves Dias went to Germany in 1856 and met editor and bookseller Brockhaus in Leipzig in 1857, who edited three books of his: Cantos, Os Timbiras and the Tupi-Portuguese dictionary, which is mentioned in this letter. The importance of this document lies not only in the fact that it is a correspondence between two highly important Brazilian personalities of the 19thcentury, but also in its importance in the history of academic practice in Brazil and its relation to Continental Europe. It is important to note that Gonçalves Dias was not only an author of poems and plays, but also a lawyer, linguist and ethnographer. The content of this letter might also be of great interest to tupinologists, as this discipline was held in high regard in Brazil at the time, largely due to the Brazilian romantics. The original text of the letter used in this translation was taken from the records of the Moreira Salles Institute, which in turn took it from the Annals of the National Library in Rio de Janeiro.
SEMIOTICS AS AN APPROACH TO THE ANALYSIS OF SYMBOLISM IN ISLAMIC ARCHITECTURAL ARTS
Authors:   Applied Science Private University, Faculty of Art and Design, Al Fahmawee Emad Al Dein Hasan
Published: June 2022

Introduction: There is a large gap in the studies and literature dealing with the concept of denotations and connotations in Islamic architecture, whether in terms of a purely geometric or artistic and aesthetic aspect. However, studies addressing these works from the ideological point of view and inferring values are scarce. This gap is a direct result of the problematic method of reading the Islamic artistic plane and its visual reading tools. Purpose of the study: We aimed is to reduce the gap between many European and Muslim researchers in understanding the symbolic connotations of various elements and the aesthetics of abstract vision in the apparent form focusing on the “spiritual component”, and relate to the conscience of the Muslim and his mind without the need for stereotypical visual representation. Methodology: By adopting semiotics as a tool for modern criticism in reading and implicit analysis of the Islamic architectural text, we linked it with the fixed ideological component present in every place and at any time — the spiritual content. Approach: In the course of the study, we interpreted analytical and implicit reading of some Islamic architectural elements and their symbolic connotations. Results: We discuss three design trends that recently appeared in the Islamic world: the direct copying of traditional elements, the contemporary trend, and distinguishing and innovating new design elements based on traditional symbolic connotations. Novelty: Contemporary buildings have lost their identity and value and have turned into soulless creatures. Therefore, it is necessary to highlight the need for returning to cultural and architectural artistic heritage and benefiting from it in finding new and contemporary design solutions using modern digital technical means.
IDENTIFYING VALUES OF CONSTRUCTIVIST HOUSES AND PALACES OF CULTURE IN LENINGRAD
Authors:   Saint Petersburg State University of Architecture and Civil Engineering, Dubrovina Natalia , Sementsov Sergei ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: June 2022

Introduction: This paper is a result of a long-term comprehensive study of Houses and Palaces of Culture in Leningrad, designed or constructed in the 1920s–1930s. It provides proofs and clarifications for those intermediate studies and conclusions that we previously performed and drew. Our main finding is a refined methodology to establish grounds for the protection of a special type of buildings — Houses and Palaces of Culture in the style of constructivism — both at the urban-planning and facility levels. Materials and methods: In the course of the study, we examined archival as well as published scientific and reference sources, including illustrations, on the subject, analyzed the master plans of Petrograd/ Leningrad, performed on-site investigations and office processing of the obtained results, and compiled detailed graphic models. Results: We identified all the planned, partially constructed, and implemented designs of a special function — Houses and Palaces of Culture — in the territory of Leningrad in the 1920s–1930s, tracked prerequisites for their creation at the urban-planning level in the Leningrad development system of the time, grouped the facilities according to the main urban-planning, architectural-and-artistic as well as cultural features, and found examples of such buildings that developed the most. Based on the identified facilities, we propose methodological approaches to identify the values of Houses and Palaces of Culture in the style of constructivism, clarifying the existing structure of grounds for protection, established for such facilities. The study showed that some of the most significant architectural-and-artistic as well as urban-planning features of Houses and Palaces of Culture are very vulnerable. Conclusions: The proposed methodology to identify (clarify) values (grounds for protection) of such facilities will ensure a more holistic, comprehensive approach to the preservation of unique architectural-and-artistic, space-and-planning as well as urban-planning features of cultural heritage facilities of the avant-garde period.
MODELING NON-STATIONARY TEMPERATURE FIELDS WHEN CONSTRUCTING MASS CAST-IN-SITU REINFORCED-CONCRETE FOUNDATION SLABS
Authors:   Don State Technical University, Chepurnenko Anton , Nesvetaev Grigory ,   Don State Technical University, Koryanova Yuliya ,   Don State Technical University
Published: June 2022

Introduction: Due to hydration heating and heat exchange with the environment during hardening, mass cast-in-situ reinforced-concrete structures exhibit non-uniform heating, which can result in early cracking and make the structures unsuitable for further use. One of the main risk factors for early cracking is the temperature difference between the center and the surface of the structure. Purpose of the study: We aimed to study how such factors as the ratio of dimensions, heat transfer conditions on the surfaces, concrete recipe, pauses during concreting and their duration affect the maximum temperature difference between the center and the surface of the structure. Methods: In the course of the study, we applied finite element modeling in one-dimensional and three-dimensional cases using the software in the MATLAB environment that we developed earlier. Results: We established that the most significant risk factors for early cracking are heat exchange conditions on the top surface, structural thickness, and the heat release rate of concrete. Verification and validation of the model were performed based on experimental data and by comparing it with a numerical solution in the ANSYS software.