bluuebunny/crossref_metadata_2025 huggingface dataset:
Real-world outcomes for Chinese breast cancer patients with tumor location of central and nipple portion
Authors: Fu Wei-Da , Wang Xiao-Hui , Lu Kang-Kang , Lu Yi-Qiao , Zhou Jie-Yu , Huang Qi-Di , Guo Gui-Long
Published: October 2022

Background

The association between tumor location and breast cancer prognosis has been controversial. We sought to explore the relationship between tumors located in central and nipple portion (TCNP) and Chinese breast cancer.

Patients and methods

A total of 1,427 breast cancer patients were recruited. There were 328 cases of TCNP and 1,099 cases of tumors in the breast peripheral quadrant (TBPQ). The chi-square test was used to compare different variables between TCNP and TBPQ groups. A one-to-one propensity score matching (PSM) was applied to construct a matched sample consisting of pairs of TCNP and TBPQ groups. Kaplan–Meier curves were used for survival analysis of disease-free survival (DFS), breast cancer-specific survival (BCSS) and overall survival (OS). The Cox proportional hazards regression model was applied to identify prognostic risk factors.

Results

The median follow-up time was 58 months. Compared to TBPQ, TCNP patients had significantly larger tumor size, more frequent metastasis to lymph nodes (LN) and more proportions of TNM stage II–III. DFS, OS and BCSS rates were markedly lower in the TCNP group as compared to the TBPQ group before and after PSM (all p < 0.05). Multivariate Cox analysis showed that TCNP was an independent prognostic factor for breast cancer. Subgroup analysis indicated that for breast molecular subtypes and TNM stage II-III breast cancer, TCNP were related to worse prognosis. Multivariate logistic regression revealed that TCNP was an independent contributing factor for LN metastasis.

Conclusion

In Chinese breast cancer, compared to TBPQ, TCNP is associated with more LN metastasis and poorer prognosis.
Characterization of microglia/macrophage phenotypes in the spinal cord following intervertebral disc herniation
Authors: Kühl Bianca , Beyerbach Martin , Baumgärtner Wolfgang , Gerhauser Ingo
Published: October 2022

Dogs frequently suffer from traumatic spinal cord injury (SCI). Most cases of SCI have a favorable prognosis but 40–50% of dogs with paraplegia and absence of nociception do not regain ambulatory abilities, eventually leading to euthanasia. Microglia and infiltrating macrophages play a crucial role in inflammatory process after SCI. However, little is known about microglia/macrophage phenotypes representing a potential target for future therapeutic strategies. In the present study, the microglia/macrophage phenotype was characterized by immunohistochemistry in the morphologically unaltered canine spinal cord (10 control dogs) and during acute and subacute SCI (1–4 and 5–10 days post injury, 9 and 8 dogs, respectively) using antibodies directed against IBA1, MAC387, MHC-II, lysozyme, EGR2, myeloperoxidase, CD18, CD204 and lectin fromGriffonia simplicifolia(BS-1). The expression of these markers was also analyzed in the spleen as reference for the phenotype of histiocytic cells. Histological lesions were absent in controls. In acute SCI, 4 dogs showed mild to moderate hemorrhages, 2 dogs bilateral gray matter necrosis and 6 dogs mild multifocal axonal swellings and myelin sheath dilation. One dog with acute SCI did not show histological alterations except for few dilated myelin sheaths. In subacute SCI, variable numbers of gitter cells, axonal changes and dilated myelin sheaths were present in all dogs and large areas of tissue necrosis in 2 dogs. Neuronal chromatolysis was found in 3 dogs with acute and subacute SCI, respectively. In control dogs, microglia/macrophage constitutively expressed IBA1 and rarely other markers. In acute SCI, a similar marker expression was found except for an increase in MAC387-positive cells in the spinal cord white matter due to an infiltration of few blood-borne macrophages. In subacute SCI, increased numbers of microglia/macrophages expressed CD18, CD204 and MHC-II in the gray matter SCI indicating enhanced antigen recognition, processing and presentation as well as cell migration and phagocytosis during this stage. Interestingly, only CD204-positive cells were upregulated in the white matter, which might be related to gray-white matter heterogeneity of microglia as previously described in humans. The present findings contribute to the understanding of the immunological processes during SCI in a large animal model for human SCI.
Organoleptic method in conducting a commodity examination of the tomato paste quality
Authors:   Ryazan State Agrotechnological University, Ryazan, Afinogenova S.N. , Morozov S.A. ,   Ryazan State Agrotechnological University, Ryazan
Published: October 2022

The article shows the role of the organoleptic method in conducting a commodity quality examination on the example of a product — tomato paste.
Development of a method for increasing the shelf life of a semi-finished sour-cream confectionery cream for public catering
Authors:   Ural State University of Economics, Yekaterinburg, Russian Federation, Zavorokhina N.V.
Published: October 2022

Extending the shelf life of a semi-finished confectionery cream used for public catering is an important and urgent task. The results of marketing research of consumer preferences by the method of questionnaire in relation to confectionery creams are presented. It was determined that the most popular types of confectionery creams are sour cream (28%), custard (22%), and cottage cheese (19%). In the course of the research, a method to increase the shelf life of semi-finished confectionery creams for public catering enterprises was developed, combining the introduction of the antioxidant retinol palmitate in the amount of 5% of the recommended daily intake with further vacuuming and shock freezing at a temperature of –30 °C, which made it possible to achieve the shelf life of the semifinished sour-cream confectionery product for 14 days in a refrigerator at a temperature of +3–4 °C in compliance with the required consumer characteristics and microbiological safety requirements. The proposed method for increasing the shelf life of the cream is applicable in wholesale kitchens and restaurants with further use of creams in public catering enterprises.
Impact of coronavirus infection on asthenic syndrome in patients with ischemic stroke
Authors:   SBHI Novosibirsk City Clinical Hospital No. 1, Novosibirsk, Russian Federation, Marushchak A. A. , Popova T. F. ,   FSBEI HE Novosibirsk State Medical University, Department of Neurology, Novosibirsk, Russian Federation, Gribacheva I. A. ,   FSBEI HE Novosibirsk State Medical University, Department of Neurology, Novosibirsk, Russian Federation, Petrova E. V. ,   FSBEI HE Novosibirsk State Medical University, Department of Neurology, Novosibirsk, Russian Federation
Published: October 2022

It is known that the presence of asthenic syndrome is characteristic of ischemic brain damage. At the same time, patients with acute cerebral ischemic stroke, who have been diagnosed with a laboratory-confirmed coronavirus infection with a mild and asymptomatic course without signs of damage to other organs, are of particular interest. The aim of the research was to identify and study the severity and duration of asthenic syndrome in patients with ischemic stroke under conditions of the coronavirus infection in order to determine the effect of asthenia on the quality of life in the post-COVID period. The subjects were patients with acute cerebral ischemic stroke with the NIHSS neurological deficit score of 12.0 [9.0;15.0], whose mean age was 58.82±3.29 years [Me=54; Mo=60.0]. The main group (38 people) included patients with laboratory-confirmed coronavirus infection without signs of damage to other organs; the comparison group (31 people) consisted of patients with AMI only, comparable to the main group in all respects, including the set of vascular risk factors. All patients underwent a clinical and neurological examination, an examination by a general practitioner and / or a cardiologist, CT using an angio mode, the MFI-20 questionnaire, A. M. Wein questionnaire, Spielberger and Khanin scale. Quality of life was assessed using a short version of the MOS SF-36‑ltem questionnaire. Statistical analysis of the obtained results was carried out via statistical programs Microsoft Office Excel 2007 (USA) and Statistica for Windows, v. 10.0. It has been established that the coronavirus infection aggravates the course of asthenic syndrome in patients with acute ischemic stroke, has a long-term effect on the recovery process, remains relevant in the post-COVID period, and is accompanied by anxiety and vegetative disorders. Organic symptomatic asthenia largely determines the course of the pathological process, affecting the general condition, performance, social adaptation and, as a result, the quality of life of the patient.
Psychological consulting of patients with anxiety phenomena using the gestalt therapy method in the conditions of the open psychiatric hospital
Authors:   Scientific and Practical Psychoneurological Center named after Z. P. Solovyov of the Moscow Healthcare Department, Meshandin I. A. , Teterina M. N. ,   Scientific and Practical Psychoneurological Center named after Z. P. Solovyov of the Moscow Healthcare Department
Published: October 2022

The article outlines the main principles of psychological consulting of patients with anxiety phenomena using gestalt therapy. The main theoretic principles of this method are described. The work is done in the Scientific and Practical Psychoneurological Center named after Z. P. Solovyov.
The structure of surgical activity and postoperative mortality for traumatic brain injury in adult population of Tyumen for 2016 2020
Authors:   Federal State Budgetary Educational Institution of Higher Education «Tyumen State Medical University» of the Ministry of Health of the Russian Federation, Tyumen, Sominov A. B. , Lebedev I. A. ,   Federal State Budgetary Educational Institution of Higher Education «Tyumen State Medical University» of the Ministry of Health of the Russian Federation, Tyumen, Vorobyov D. P. ,   Federal State Budgetary Educational Institution of Higher Education «Tyumen State Medical University» of the Ministry of Health of the Russian Federation, Tyumen; State Budgetary Healthcare Institution of the Tyumen Region «Regional Clinical Hospital No. 2», Tyumen, Gaibov S.‑S. H. ,   Federal State Budgetary Educational Institution of Higher Education «Tyumen State Medical University» of the Ministry of Health of the Russian Federation, Tyumen; State Budgetary Healthcare Institution of the Tyumen Region «Regional Clinical Hospital No. 2», Tyumen, Zakharchuk E. V. ,   Federal State Budgetary Educational Institution of Higher Education «Tyumen State Medical University» of the Ministry of Health of the Russian Federation, Tyumen; State Budgetary Healthcare Institution of the Tyumen Region «Regional Clinical Hospital No. 2», Tyumen, Nesterova O. A. ,   Federal State Autonomous Educational Institution of Higher Education «University of Tyumen», Tyumen,
Published: October 2022

Traumatic brain injury (TBI) is a complex multidisciplinary problem due to high disability and mortality rates associated with it. What is more, due to a number of behavioral and social factors, the young working population is especially predisposed to this type of injury. In order to optimize preventive measures and treatment protocols it is crucial to have thorough understanding of TBI regional features. The research objective was to analyze the structure of surgical interventions and outcomes for adult TBI patients in Tyumen during 2016‑2020. The inclusion criteria were as follows: confirmed TBI diagnosis (S06 ICD-10 code), adult age (18 years old and over), and trauma acquisition during 2016‑2020. We analyzed 3,558 TBI cases. 641 (18.0 %) patients required surgical treatment, 826 surgeries were carried out in total. The average annual number of surgeries was 162.5. Most surgeries were due to subdural hematoma — 316 patients. Postoperative mortality rate was 15.6±3.2 %; 100 patients had polytrauma. The average surgeries-to-patient ratio was 1.3:1 and 3.4:1 for those who had more than one surgical intervention; 224 patients were operated on for TBI more than once. Our research indicated no statistically significant dynamics of the number of annual operations, outcome structure and mortality rates within the studied population and during the studied period.
Subsequent measurement of medical devices and medicines in the pharmacy entity’s statement of financial position
Authors:   Federal State Budgetary Educational Institution of Higher Education “Plekhanov Russian University of Economics”, Moscow, Russia, Tarasova O.N.
Published: October 2022

The article presents the essential aspects of medical devices and medicines, the importance of this market for the population of the country. The modern dynamics and directions of development of the medical devices and drugs market in Russia are revealed, the primary role of state regulatory bodies in this process is noted. The author outlined the current requirements for the subsequent measurement of inventory values in the statement of financial position, the reflection of its results in the accounting. The article covers not only accounting rules for evaluation after recognition of medicines and medical products by pharmacy organizations, but also tax aspects.
Influence of accounting rules for financial instruments on indicators of economic analysis
Authors:   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhniy Novgorod”, Nizhniy Novgorod, Russia, Druzhilovskaya T.Y. , Dobrolyubov N.A. ,   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhniy Novgorod”, Nizhniy Novgorod, Russia
Published: October 2022

Accounting of any object provides information to reflect this object in the financial statements. Indicators of financial statements serve as the basis for calculating indicators of economic analysis, allowing to give an objective assessment of the activities of organizations. At the same time, changes made to accounting standards may lead to changes in the accounting rules for certain items. This may affect the value of these objects in the reporting, which in turn may lead to changes in the value of certain indicators of economic analysis. The value of the objects reflected in the statements may also be influenced by the organization’s choice of one or another option for accounting for the object permitted by accounting standards. This article examines the impact on the indicators of economic analysis of the rules for accounting for financial instruments of organizations. The significance of these objects in the modern activities of organizations, including healthcare organizations, is steadily increasing. At the same time, the rules for accounting for financial instruments can currently be changed (this is evidenced by the Russian accounting reform program). There are also problems in the choice of options for accounting for financial instruments by organizations on the basis of existing accounting standards. All this may affect the calculation of economic analysis indicators, including the values of financial instruments. This determines the relevance of studying the dependence of economic analysis indicators on the value of financial instruments formed in the reporting of organizations. The research methods were comparison, analysis, synthesis, grouping method, systemic and logical approaches. As a result of the study, the aspects of accounting of financial instruments that affect the indicators of economic analysis have been identified, and this influence has been systematized.
Formation of an information and analytical base for assessing the efficiency of capital use: Russian and international aspects
Authors:   Federal State Budgetary Educational Institution of Higher Education “Plekhanov Russian University of Economics”, Moscow, Russia, Plaskova N.S.
Published: October 2022

The article presents methodological approaches to the formation of a reliable information and analytical base for assessing the use of capital, focused on the requests of external stakeholders and internal management of the organization. On the basis of a critical analysis and generalization of conceptual domestic and international approaches to determining the essence of an enterprise’s capital as an accounting and analytical category, its functions and components, its sources of formation and directions of use in modern business conditions are supplemented and clarified. A comparative analysis of the features of disclosure of information about capital and its elements in Russian and international financial statements is carried out. A multifactorial model for assessing the efficiency of capital use and the impact of external and internal factors on the return on capital has been developed.
Получение высокочистого поликристаллического кремния из моносилана
Authors:   АО «НПП «Салют», Аношин О.С. , Зайцев А.В. ,   АО «НПП «Салют», Гришнова Н.Д. ,   АО «НПП «Салют», Архипцев Д.Ф. ,   АО «НПП «Салют», Скосырев А.И. ,   АО «НПП «Салют», Банников Н.А. ,   АО «НПП «Салют», Туманов А.Ю. ,   АО «НПП «Салют», Котков А.П. ,   АО «НПП «Салют», Т.В. Т.В. ,   Институт химии высокочистых веществ РАН, Андреев Б.А. ,   Институт физики микроструктур РАН, Курицын Д.И. ,   Институт физики микроструктур РАН
Published: October 2022

Высокочистый поликристаллический кремний (ПКК) в виде стержней является исходным материалом для получения высокоомного (ρ > 1000 Ом·см) монокристаллического кремния (МКК) методом бестигельной зонной плавки (БЗП). Высокоомный МКК необходим для изготовления высоковольтных и сильноточных приборов, а также для изготовления кремниевых подложек для эпитаксии нитрида галлия и КМОП-технологии. Производство высокочистого ПКК в России в настоящее время отсутствует. В докладе представлены результаты получения стержней ПКК длиной до 750мм и диаметром до 110 мм в одностерженевом реакторе с выходом целевого продукта более 90 %.
HUBUNGAN KONDISI SOSIAL EKONOMI MASYARAKAT PETANI TERHADAP DEGRADASI LAHAN DI DAS ALO POHU PROVINSI GORONTALO
Authors: Salote Moh Khamal , Lihawa Fitryane , Dunggio Iswan
Published: October 2022

The purpose of the study was to analyze the socioeconomic conditions of the community and their relationship to land degradation in the Alo Pohu watershed, Gorontalo Province. The research method used in this study is a survey method with a total population of 79,828 people. The sampling method is a purposive sampling method with the criteria of people working as farmers determining the number of samples based on the Slovin formula, and the number of samples is 392 people. The socioeconomic parameters studied are education level, knowledge, income, household expenses, land ownership, and the number of dependents. In addition, perceptions and parameters of land degradation are determined based on the criticality level of the land. The data collection method is a questionnaire method. The data analysis used is quantitative and descriptive. A cross-table analyzes the relationship between socioeconomic conditions and land degradation. The results showed three socioeconomic parameters that significantly affected land degradation in the Alo Pohu watershed: education level, land ownership, and knowledge of critical land.
INTEGRASI BUDAYA KAMPUNG NAGA SEBAGAI MITIGASI BENCANA DI KABUPATEN TASIKMALAYA PROVINSI JAWA BARAT
Authors: Marlyono Setio Galih , Indrianeu Tineu , Singkawijaya Elgar Balasa
Published: October 2022

Disasters are a threat to all people living in Indonesia, as a logical consequence of Indonesia's geological conditions. Almost all regions of Indonesia have the potential for disasters. Especially for the West Java Province, especially the Regency on the south coast which has various kinds of disaster threats, such as Earthquakes, Tsunamis, Landslides, and even Fires. Likewise in Tasikmalaya Regency, in this case the Naga traditional village community. The touch of local wisdom in disaster mitigation is very interesting to learn in Kampung Naga. The research method uses a descriptive method with a field survey technique (Field Study). The results showed that, for earthquake disasters, it was minimized by the use of the dominant house material from bamboo and consuming the system of houses on stilts to dampen vibrations. In the case of landslides, on sloping land, this is handled by using stone terraces. As for the fire disaster, using a method of using a different room woven system for each room to minimize the appearance of fire so that it can be detected from outside the house.
TÜRKİYE'DE SİVAS’TAKİ BEBEK ÖLÜMLERİ VE NEDENLERİNİN İNCELENMESİ
Authors: Akova İrem , Güneş Bal Şeyma , Arslaner Seyhan , Uygun Tunahan , Hasta Seyhan
Published: October 2022

Bu araştırmanın amacı Sivas’taki bebek ölümlerini ve ölümlerin nedenlerini tespit etmekti. Bu tanımlayıcı çalışmada, 2013-2020 yılları arasındaki bebek ölümleri Sivas İl Sağlık Müdürlüğü verileri kullanılarak incelendi. Bebek ölüm hızı, neonatal ölüm hızı, erken neonatal, geç neonatal ve post neonatal ölüm hızları hesaplandı ve bunların anneye ve bebeğe ait bazı özelliklerle ilişkisi değerlendirildi. Değerlendirmede yüzdelik dağılımı ve ki kare testi kullanıldı. Yanılma düzeyi p<0,05 alındı. Çalışmamızda Sivas’taki bebek ölümlerinin 2013-2020 yılları arasında azaldığı ve 2020 yılında binde 7,06 olduğu tespit edildi. Neonatal ölümler içerisinde erken neonatal ölümler en sık görülendi (2020 yılında %54) ve son yıllarda artma eğiliminde olduğu saptandı. Erkek bebeklerde (%54,4), 35 yaş altı annelerin bebeklerinde (%81,1), 2. ve 3. gebeliklerde (%42,3), 37 haftanın ve 2500 gr’ın altındaki doğumlarda (sırasıyla %62,4; %61,3) bebek ölümleri daha fazlaydı. Konjenital anomaliler (%10,6), akciğer yetmezliği (%9,5), respiratuar distres sendromu (%7,9), sepsis (%7,4) ve prematürite (%6,5) bebek ölümlerinin başlıca nedenleri olarak saptandı. Konjenital anomalileri erken dönemde saptamak, prematürite, sepsis ve solunumsal problemlerin azaltılması adına gebelik dönemi ve doğum sonrası izlemlerinin çok iyi yapılması ve saptanan riskli gebelerin takiplerinin aksatılmaması önerilebilir.Anahtar kelimeler: Bebek ölümü, ölüm nedeni, prematüre bebekler, doğumsal kusurlar.
DÜNYADA VE TÜRKİYE’DE AŞILANMA TUTUMU VE COVID-19 AŞILARINA BAKIŞ
Authors: Akbulak Mert Aykut , Çöl Meltem
Published: October 2022

Aşılama, en maliyet etkili toplum müdahalelerinden biridir ve her yıl milyonlarca ölümü engelleyerek insanların daha uzun ve daha sağlıklı yaşamasına katkı sağlamaktadır. Aşıyla önlenebilen bulaşıcı hastalıkların ortaya çıkışının engellenmesi ve salgınların önlenebilmesi için, toplumda belirli bir bağışıklık düzeyinin üzerine çıkılması gerekmektedir. Hedeflenen bağışıklık düzeylerine ulaşmanın önündeki temel engeller arasında, aşı tedarik ve dağıtımıyla birlikte aşı reddi ve aşı tereddütü de bulunmaktadır. Son yıllarda dünyada ve ülkemizde yaygınlığı giderek artan aşı reddi ve aşı tereddütü, toplumdaki tüm bireylerin sağlığını tehdit etmektedir. Yapılan çalışmalarda, aşı reddi ve aşı tereddütünün en sık nedenleri arasında, aşı güvenliğine ve yan etkilere yönelik endişeler ile aşılama ve önemi konusunda bilgi ve farkındalık eksikliği gösterilmektedir. Ayrıca, aşılara karşı sergilenen olumsuz tutum, diğer aşılarda olduğu gibi COVID-19 aşılamasında da hedeflenen oranlara ulaşılmasına engel olmaktadır. Aşılama oranlarını artırmak için, dünya genelinde ülkelerde zorunlu aşılama da dahil olmak üzere çeşitli aşılama politikaları uygulanmaktadır. Bu derlemenin amacı, aşı tereddütünün ve aşı reddinin nedenlerini, dünyadaki ve Türkiye’deki mevcut durumu, ülkelerdeki aşılama politikalarını ve yasal durumu ortaya koyup çözüm önerileri sunmaktır.Anahtar kelimeler: Aşılama, aşı reddi, aşı tereddütü, COVID-19.
EBEVEYN AŞI TEREDDÜTTÜ ÖLÇEĞİNİN UYARLANMASI: GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: Alp Servet , Oral  Kara Nurdan
Published: October 2022

Bu araştırmanın amacı, SAGE çalışma grubu tarafından geliştirilen Shapiro ve ark. (2018), tarafından geçerlik ve güvenirliği test edilen Aşı Tereddüttü Ölçeği’ni Türk kültürüne uyarlamak ve ölçeğin Türkçe versiyonunun geçerlik ve güvenirliğini sağlamaktır. Ölçeğin özgün hali bir devlet üniversitesinin Yabancı Diler Yüksekokulu’nda görev yapmakta olan bir öğretim üyesi tarafından Türkçeye çevrilmiştir. Elde edilen Türkçe çeviri, İngilizce ve Türkçe ’ye hâkim sağlık bilimleri alanındaki üç akademisyen tarafından tartışılmış, anlam ve gramer açısından gerekli kontrolleri yapılarak değerlendirilmiştir. Değerlendirme neticesinde elde edilen Türkçe ölçek, Yabancı Diler Yüksekokulu’nda görev yapmakta olan farklı bir öğretim üyesi tarafından İngilizce ’ye çevrilmiştir. Daha sonra İngilizce ‘ye çevrilmiş ölçek ile ölçeğin özgün hali karşılaştırılmış ve yeniden akademisyen görüşüne başvurulmuştur. Akademisyenlerin belirtmiş oldukları düzeltme ve öneriler dikkate alındıktan sonra ölçeğe son hali verilmiştir. Nihai hali verilerek oluşturulan ölçek ile Burdur ili merkezinde yaşayan 355 ebeveynden veri toplanmıştır. Ölçeğin psikometrik (güvenirlik ve geçerlik) özelliklerini test etmek amacıyla McDonald’s Omega ve Cronbach Alpha yöntemi ile güvenirliği, açımlayıcı/keşfedici ve doğrulayıcı faktör analizi ile yapı geçerliği test edilmiştir. Ayrıca ölçek maddelerinin ayırt edicilik gücünü belirlemek amacıyla yapılan madde analizi sonucuna göre ölçek maddelerinin yeterli ayırt edicilik gücüne sahip olduğu bulunmuştur. Gerçekleştirilen analizlerden elde edilen sonuçlar alan yazınında genel kabul görmüş eşik değerleri sağladığından ölçeğin güvenilir bir ölçüm aracı olduğu ifade edilebilir.
3D Stochastic Network Modeling and Investigation of Network Size Effect on the Porous Media Structure of Ion Exchange Catalyst Amberlyst-35 with Computer Programs
Authors: ŞİMŞEK Veli , MURTEZAOĞLU Kırali
Published: October 2022

In the present paper, the investigation was focused on the physical characterization and determination of porosity for an ion exchange catalyst called Amberlyst-35, which produces environmentally benign gasoline using 3D network modeling (3DNM). In addition, the effect of the different pore size distributions (PSD) has been investigated in porous media (PM). First, the mercury porosimetry (MPo) experiment was carried out to determine the porosity of the Amberlyst-35. Second, the KALINET program was run by Compact Visual Fortran (CVF) and Graphical Input/Output (GINO) for modeling porous structures. Then, the SECTION program was used for different porous 3D random images. The theoretical penetration curve was drawn using data obtained from the KALINET program and fitted to the experimental penetration values of Amberlyst-35 by changing the number of pores in each pressure interval of the PSD. The PSD was a 3D network model size of (N) = 30x30x30, 40x40x40, 50x50x50, which included 83,700-196,800-382,500 pores, respectively. On the other hand, various sections of the 3D stochastic images of the pore network were obtained from the SECTION program. Finally, 3D network images were drawn by the KALINET3D computer program. The MPo method has been applied using computer programs (with desktop computers). Moreover, it was found that the same results were obtained for both the theoretical and experimental data of MPo.
Gist sincrónico con adenomioma gástrico: Reporte de caso y revisión de la literatura
Authors: Cardeña-Mamani Rakel , Parra-Montenegro Luis , Aita-Campodonico Giorgio , Torres-Samamé Julio , Flores-Alvarez Willys
Published: October 2022

Introducción: La colisión de dos tumores de diferente estirpe celular en un mismo órgano es infrecuente; a pesar de las asociaciones descritas en la literatura, el hallazgo de GIST con adenomioma en sincronismo, llama aún más la atención debido a sus distintos orígenes celulares. Reporte de caso: Presentamos el caso de una paciente mujer de 57 años de edad, quien es sometida a cirugía de resección doble en cuña, y distintos exámenes incluido el anátomo-patológico. Conclusión: Se demuestra la presencia de tumores sincrónicos, GIST gástrico y adenomioma gástrico, a pesar de la infrecuencia de este hallazgo.
Epidemiología y características de las patologías neuroquirúrgicas en un hospital peruano nivel III-1 de alta complejidad. Periodo 2008-2020
Authors: Alarcón-Braga Esteban A. , Cornejo-Venegas Gonzalo , Castillo-Soto Ana , Silva-Parra Kevin , Glavic Vicko B.
Published: October 2022

Introducción: existe una alta carga de enfermedad neuroquirúrgica en el mundo. La información sobre patología neuroquirúrgica en Perú es limitada. Objetivo. El objetivo del estudio es describir las características epidemiológicas y la distribución temporal de la patología neuroquirúrgica en un centro de alta complejidad. Material y Métodos: se realizó un estudio transversal analítico usando el registro de cirugías del servicio de neurocirugía del Hospital Nacional María Auxiliadora, en Lima-Perú entre 2008 y 2020. Se categorizó a los diagnósticos según la patología primaria en 10 categorías; y los diagnósticos específicos correspondientes a cada patología primaria. Se describieron frecuencias absolutas y relativas según patología. La distribución temporal se describió mediante un mapa de calor. Se usó la prueba de chi cuadrado para evaluar asociación entre los diagnósticos y el sexo. Resultados: se realizaron 2948 procedimientos quirúrgicos. La mediana de la edad fue de 38 años; y el 66,7% fue del sexo masculino. Los diagnósticos de traumatismo encefalocraneano, hidrocefalia y patología vascular representan el 60,0% de la carga de enfermedad neuroquirúrgica en el centro de estudio. El 20,2% de los TECs fueron hematomas subdurales crónicos y el 19,4% fueron hematomas epidurales. El 7,4% de todos los procedimientos fueron reintervenciones. Se encontró asociación entre el sexo y el diagnóstico primario (p < 0.001). Conclusiones: Los diagnósticos primarios más frecuentes fueron el traumatismo encefalocraneano, la hidrocefalia y los eventos vasculares. Es necesario comprender mejor el perfil de carga de enfermedad neuroquirúrgica en Perú.
Situación de la enfermedad renal crónica en la Región Junín, Perú
Authors: Arellan-Bravo Luis , León-Gonzales Robert
Published: October 2022

Carta al Editor (Sin resumen)
Conocimiento sobre viruela del mono en profesionales de la salud, Lima-Perú
Authors: Navarrete-Mejía Pedro Javier , Velasco-Guerrero Juan Carlos , Sullcahuaman-Valdiglesias Edith
Published: October 2022

Introducción: la pandemia por SARS-CoV 2 nos demostró que no estábamos preparados, que no se repita. Objetivo: conocer el nivel de conocimiento sobre etiología, síntomas, tratamiento y prevención de la enfermedad viruela del mono en profesionales de la salud. El estudio: observacional-descriptivo, incluyó 251 profesionales de la salud, ambos sexos participación voluntaria. Se elaboró un cuestionario incluyéndose las variables edad, sexo y preguntas sobre la enfermedad viruela del mono; análisis descriptivos de los datos. Hallazgos: bajo conocimiento sobre etiología, síntomas, tratamiento y prevención de la enfermedad. Menor conocimiento sobre formas de contagio (21,9%), tiempo de incubación (21,9%), características del virus (24,3%) y diagnóstico laboratorial (25,1%); mayor conocimiento sobre contagiosidad en periodo de incubación (61,0%), presencia de erupciones como característica de la enfermedad (53,8%) y no existencia de tratamiento específico (52,2%). Conclusión: conocimiento bajo; urge la formulación de estrategias para poder enfrentar, de ser necesario, los posibles casos.
El que compone no baila
Authors: Mansilla Pons Ramiro
Published: October 2022

El que compone no baila es un estudio sobre la composición musical en el ámbito de la danza contemporánea a partir de una veintena de producciones realizadas en la ciudad de La Plata entre 2006 y 2018. A través del análisis de las obras, de los comentarios de compositores y de coreógrafos, y de la experiencia de su autor, el libro invita al lector a un recorrido estético por la rica y diversa escena dancística platense. Para ello, el autor propone una observación de las distintas instancias de producción de música para danza, describiendo y sistematizando las funciones que cumple la música, las formas en que se la comienza a componer, los códigos verbales utilizados entre músicos y coreógrafos, las fuentes sonoras habituales y los usos de la voz.
Renewable Energy Production and Storage Options and their Economic Impacts in Hungary
Authors: Németh Márton
Published: October 2022

The study reviews the most relevant renewable energy sources, focusing on their possible application, economic aspects and potential for Hungary. Feasibility and economic analysis is made for plant-sized photovoltaic devices, wind turbines, geothermal power plants and biomass power plants. It was found that solar cell technology has the highest revenue. However, its further spread is limited by several factors, such as the reactive effect on the energy market, grid problems, and weather dependency. A possible solution for these problems is to use energy storage systems. For the sake of simplicity, only the economically mature technologies are investigated, including pumped hydroelectric storage, batteries, green hydrogen production, and thermal energy storage connected to a heat power plant. The payback calculations require a simple simulation algorithm to calculate the revenue using Hungarian data. With the simulation, the most important economic indicators are estimated. As a result of these calculations, we suggest a pumped hydroelectric storage to be built, or if it is impossible, the Paks 2 nuclear plant should be completed with a thermal energy storage facility.
Lessons Learned from an Operational Smart Grid Through the Example of a Local Government in Hungary
Authors: Piricz Noémi , Révész Balázs
Published: October 2022

The steadily growing global demand for electricity, sustainability expectations, the global Covid epidemic and the Russian-Ukrainian war are also affecting the electricity supply chain. In our study we will focus on the smart grid, the modern smart electricity network of the near future, from a Hungarian perspective, with management approach. Hungary’s newest and most complex smart grid is analysed using the case study method. We investigated the actors of the smart grid and were interested in how the cooperation between the parties was, what learning processes they experienced, and what risks they saw and see now. Our results show that customers and contractors are mutually satisfied; in addition to the numerical benefits, each party also values the learning processes in different areas. The risks identified stem from modern technology, complexity, novel solutions and operational mechanisms, but geopolitical, global economic uncertainties and shortages also have an impact.
Face à la crise sanitaire : la fabrique de la continuité pédagogique
Authors: Salah Sarra Ben
Published: October 2022

La crise sanitaire due au Covid-19 et la fermeture des établissements scolaires ont mis sur le devant de la scène la question de la continuité pédagogique. Présentée comme une interrogation nouvelle, elle avait déjà été mobilisée dans les plans de prévention et de lutte contre une pandémie grippale publiés entre 2004 et 2010. Cet article a pour ambition de proposer une analyse historique de ce concept, en mettant en perspective la manière dont l’école a réagi à la crise du Covid-19 en la comparant à des situations de crises sanitaires antérieures (celles de la H5N1 et de la H1N1). L’étude de ces plans permet de faire remonter des continuités et des discontinuités dans la définition de la continuité pédagogique. L’idée est aussi de se concentrer sur l’évolution des attentes du ministère vis-à-vis des enseignants et de leur rôle en cas de fermeture des établissements scolaires et donc de mise en place de la continuité pédagogique. Nous voulons comprendre comment l’organisation de l’école, instaurée dans l’urgence pendant le confinement de mars 2020 à mai 2020, réactualise des éléments pensés en amont par le ministère de l’Éducation nationale.
Tolimenses que dejan huella. Volumen 3
Authors: Hernández Esquivel Angel , Melo Salazar Antonio , Hernández Quintero Hernando Antonio , Castaño González Yezid , Trujillo Muñoz Augusto , Reyes Alvarado Alfonso , Reyes Alvarado Yesid
Published: October 2022

El presente libro —el tercer volumen de la obra— incluye crónicas sobre ocho tolimenses cuyas acciones tuvieron importante incidencia en la vida nacional. En sus páginas transitan vivencias, anécdotas y relatos sobre los siguientes tolimenses: Manuel Murillo Toro, Alberto Castilla Buenaventura, Alfonso López Pumarejo, Darío Echandía Olaya, Rafael Parga Cortés, Alfonso Palacio Rudas, Rafael Caicedo Espinosa y Alfonso Reyes Echandía.
Difficulties in measuring and assessing the socio-psychological climate in the service teams of internal affairs bodies
Authors: Zlokazov Kirill , Yurenkova Vitaliya , Rozhkov Anton
Published: October 2022

In the system of measures for the moral and psychological support of the professional activities of employees of the internal affairs bodies, the diagnosis of the socio-psychological climate is becoming increasingly important.

Along with understanding the significance of the socio-psychological climate as an important psychological phenomenon, the need for further improvement of the tools and procedures used to measure it is obvious. In addition to utilitarian reasons caused by psychometric shortcomings of the instrumentation, errors in the organization of psychodiagnostic procedures for studying it, there are reasons of a different level.

The article is devoted to the analysis of the difficulties that exist in measuring and evaluating the socio-psychological climate in the service teams of the internal affairs bodies. The authors highlight the difficulties of the methodological level, which they see in the complexity of the phenomenon of «sociopsychological climate» and the variety of scientific approaches in its description, as well as the difficulties of the instrumental level, which lie in the fact that in many ways the methods known and used by psychologists of the internal affairs bodies have lost their effect. novelties and their resistance to falsification has decreased,

which led to a decrease in the effectiveness of measuring procedures, does not allow to fully identify the reasons for the deterioration of the socio-psychological climate in the unit and predict with a high degree of probability the climate in a certain group in the long term. In the article, the authors substantiate the need to improve the practice of psychological measurement of the socio-psychological climate, describing in detail various theoretical approaches, scientific methods of cognition, particular methods of measurement and evaluation.
Using digital capabilities for information processing in modern risk management
Authors: Kharlamov A. V. , Osipov K. A.
Published: October 2022

Aim. The presented study examines modern factors affecting the functioning of risk management, specify the requirements for information and services for retrieving and processing it to make effective management decisions aimed at minimizing or eliminating risks.

Tasks. The authors specify the challenges of risk management in the context of economic instability to preserve existing positions and substantiate directions for development; determine the stages of further transformation of risk management corresponding to the strategic guidelines for the development of business structures and describe them with an emphasis on existing problems and the opportunities for solving them; investigate the nature of the increasing importance of information analysis within the framework of risk management and the necessity and possibility of attracting third-party organizations for this purpose; identify and describe changes taking place in risk management in the context of digital transformation, accompanied by changes in information analysis and the active promotion of related services by the IT sector.

Methods. This study uses general scientific research methods (systems and logical approaches) and the methods of strategic and situational analysis to determine cause-and-effect relationships and describe the obtained results.

Results. The authors propose an original concept substantiating the increasing importance of the joint work of business structures and their partners providing services for retrieving and processing information in the interests of risk management. Emphasis is placed on the need to protect commercial information and prevent its leakage. This concept makes allowance for current trends in the active development of the IT sector, the Internet economy, and economic security, including under economic sanctions. The proposed recommendations can serve as a basis for a comprehensive model that would make it possible to develop directions for improving the risk management system, substantiating the effective behavior of an entrepreneurial structure in the presence of economic and non-economic risks.

Conclusions. The study proves that the development of a modern entrepreneurial structure increases the importance of the functioning risk management system. Factors that ensure the development of risk management and prevent it from functioning normally are identified. Based on this, recommendations for organizing effective management in this area of management activity are proposed.
RELATIONSHIP BETWEEN FREQUENCY, DURATION AND TIME OF BOTTLE FEEDING WITH RAMPAN CARIES
Authors: Lestari Anisa Dwi , Putri Megananda Hiranya , Restuning Sekar , Laut Deru Marah
Published: October 2022

Rampant caries is a caries that occurs in a short period of time and it usually occurs in children who have a tendency to drinking bottle milk. Bottle feeding is one of the oral bad habits and its impact depends on the frequency, duration, and time of doing it. The purpose of this study was to analyze the relationship between the frequency, duration and time of bottle feeding with rampant caries, the results can be seen by being tested through a software called SPSS. This was an analytic research study. Design of this study was a cross-sectional design with samples are children from Kemala Bhayangkari 42 Kindergarten Bandung and their parents. Samples were selected purposively and met the inclusion criteria of 32 parents and 32 children. The process of obtaining data through direct interviews with the parents of respondents using questionnaires and direct examination of respondents. The results of the chi-square test with the likelihood ratio value showed that the p-value of the frequency, duration, and time of bottle feeding with rampan caries is 0.014; 0.000, and 0.002. Conclusion: there is a significant relationship between the frequency, duration, and time of bottle feeding with rampan caries (p-value < 0.05).
MATHEMATICAL MODELING AND METHODS OF SELECTION OF POROUS CEMENT CONCRETE COMPOSITION
Authors:   National Transport University, Kyiv, Ukraine, Gameliak Igor , Rutkovska Inessa ,   National Transport University, Kyiv, Ukraine, Filishchuk Mariia ,   M.P. Shulgin State Road Research Institute State Enterprise – DerzhdorNDI SE, Kyiv, Ukraine
Published: October 2022

Introduction. The construction and operation of airfield elements such as runways, taxiways, and parking places that meet the requirements of regulations and modern methods of road works are significant in the system of aviation security in modern conditions. In order to ensure safe conditions for landing aircraft on the runway during downpours and heavy rains, porous cement concrete should be used as the surface source, which will further reduce hydroplaning. Research problem. Due to a large number of aircraft crashes and their rolling outside the runway, which is associated with the frequent failure of the coating to perform drainage because of unfavorable weather conditions (including thunderstorms, showers, and snowfalls), there is the need to improve the existing structures of airfield pavements or to develop new technologies to improve the drainage of pavement and, accordingly, the safety of takeoff and landing of aircraft on the runway. The use of modern airfield pavement structures made of porous cement concrete with drainage properties is one of the ways to solve this problem. The purpose of the study. The research aims to prove that the use of porous cement concrete in mathematical modeling of porous cement concrete composition and improvement of airfield structure will guarantee safe conditions for takeoff and landing and taxiing of aircraft on the runway. Materials and methods. During the research, the analysis of monographs, normative documentation, methodical instructions and recommendations was made. These documents establish requirements concerning the selection of materials for porous cement concrete structure, its use in the construction of elements of an airfield, and their exploitation. Results. The feasibility of using different methods of design and selection of the design and selection of porous cement concrete is proved. Conclusion. The revision and analysis of the literature showed that in order to obtain products and structures with specified properties the most appropriate approach is the use of several methods simultaneously to project and select components for the composition of porous cement concrete. The benefits of the simultaneous use of several methods such as the reduction of information processing time, the improvement of mixture quality, the flexibility of the model to adjustment, the simplification of analysis, and the comparison of indicators of mathematical modeling and laboratory tests were highlighted.
CORRELATION OF EUSTACHIAN TUBE FUNCTION WITH TYMPANOPLASTY OUTCOME
Authors: J. K. Yashveer , Soni Smita , Kumar Tiwari Ankit
Published: October 2022

Background– Eustachian tube play a vital role in the pathogenesis of middle ear cleft disease.Normal eustachian tube
function (ETF) is responsible for successful tympanoplasty outcome. Pre operative ETF test should be done. Aim &
objective– To evaluate the role of Eustachian tube function in successful graft uptake in tympanoplasty. Method – a
prospective study was done on 50 patients, with mucosal type of chronic otitis media (COM). Eustachian tube function
(ETF) was assessed with various methods like impedance audiometry (Toynbee's method),methylene blue dye test etc,
and correlation of graft uptake with preoperative ETF was done. Result– Out of 50 patients,78% had normal tubal
function and 22% had partially impaired tubal function. Tympanoplasty was successful in 92.3% patients with normal
ETF and 54.5% patients with partially impaired ETF. Conclusion– There is a strong association between ETF and graft
uptake.Thus,proving that eustachian tube plays a major role in the graft uptake.So preoperative ETF should be done.
A STUDY OF FOSSA OVALIS : HOW THE MORPHOMETRY AND LOCATION AFFECTS TRANSSEPTAL APPROACH TO LEFT ATRIUM.
Authors: Banerjee Anirban , Samanta Shubhrangsu , Ramkrishna Sri
Published: October 2022

Background- Fossa Ovalis (FO) surrounded by limbus are embryological remnants in inter atrial septum of heart. By
Trans-septal approach, towards the left heart chambers, floor of FO is punctured to perform various types of diagnostic
and therapeutic procedures. Variable position and morphometry of FO remains main challenge. Materials and
Methods– 30 heart specimens were procured from properly embalmed cadavers. FO was Inspected in interior of the
right atrium. Shapes, diameters, position of FO were determined by Vernier callipers. Probe patency test was performed
in cases of Patent Foramen Ovale (PFO). occurrence of PFO is 23.3% (7 out of 30 hearts). The average Result- transverse
diameter of FO was 11.68 mm and average vertical diameter was 13.70 mm. Most of the FOs ware oval with longer
vertical diameter. In 26 cases (86.6%) limbus is raised and in 4 it is totally flat with the surface of IAS. In 22 hearts, wall of
FO were thinner than rest of inter atrial septum (IAS). In one case Chiari strands are found in the floor of FO. Conclusion–
Raised limbus of FO prevents slipping of needle while puncturing. Small FO, Chiari strands or multiple cardiac
anomalies are unfavourable for TS puncture. To perform Left atrial pressure measurement, and in different cardiac
surgeries proper visualization and knowledge of FO is very important.