bluuebunny/crossref_metadata_2025 huggingface dataset:
To assess the perception of the young adults regarding child sexual abuse
Authors: Dangi Ravi Rai , Jadon Ritu Singh , Chakraborty Snigdha
Published: April 2022

Background and Objectives: Child sexual abuse (CSA) is a worldwide issue with serious long-term consequences. "The involvement of a child in sexual behavior that he or she does not completely grasp and is unable to provide informed permission to, or for which the kid is not developmentally equipped, or else that violates the laws or social taboos of society," according to the World Health Organization (WHO). The present study was aiming towards the perception of CSA among young adults. Methods: A cross sectional survey design was used for this research study. For data collection, an online tool was prepared. The data collection tool was constructed into two sections, first section deals with demographic data like age, gender, occupation, etc. whereas the second section were having Likert scale. Tool was shared to potential participants via online social media applications. After screening, total 1000 samples were selected for this study. Results: This study reported that maximum 64% were males and 36% were females. In age, maximum 43.50% participants were from 18-22 years of age group, 33.60% were from 23-27 years of age group and 22.90% were from 28-32 years of the age group. Demographic data was also associated with the research findings.
Sars-COV-2 infection leads to neurodegenerative or neuropsychiatric diseases
Authors: Dubey Anubhav , Ghosh Niladry Sekhar , Rathor Virendra Pratap Singh , Patel Shweta , Patel Bhupendra , Purohit Debashis
Published: April 2022

The current COVID-19 epidemic caused by the new SARS-CoV-2 has severely harmed global healthcare (severe acute respiratory syndrome coronavirus). COVID-19's pulmonary and cardiovascular effects have been known from its inception, but its causes, mechanisms, and neuropath logical consequences remain unknown. Our research focused on neurological problems in COVID-19 patients, as well as probable SARS-CoV-2 infection routes like hematogenous, direct/neuronal, lymphatic tissue, cerebrospinal fluid, or infiltration by infected immune cells. Late December 2019 in Wuhan, China, a mysterious viral pneumonia struck. The disease was caused by a new corona virus. Corona virus infection spread rapidly from person to person in 2019. The WHO has called it a global public health emergency (WHO). Activation of NF-B in SARS-CoV-2 infection may be linked to immune cell pathogenicity, cytokine storms, and multi-organ failure. COVID-19's inhibition of the NF-B signaling pathway shows promising therapeutically. Inhibiting IKK phosphorylation, a critical downstream consequence of the NF-B signaling cascade, reduces COVID-19 levels. All three disorders have been linked to COVID-19 gene mutations. This study provides a biological basis for future research on COVID-19-related neurological disease. W
An updated review on morpholine derivatives with their pharmacological actions
Authors: Meher Chaitanya Prasad , Purohit Debashis , Kumar Ashish , Singh Raghuvendra , Dubey Anubhav
Published: April 2022

The invention of newer chemical entities, which have some therapeutically worth is always a great challenge. It is no doubt that it is a lengthier process. We have several drugs in the market for treatment of wide variety of diseases. The marketed drugs available may be heterocyclic or non-heterocyclic derivatives. Always it was found that heterocyclic derivatives have wide variety of pharmacological activity. The intension of this review is to highlight one of the important heterocyclic rings i.e.: Morpholine. Several works have been done on this nucleus, which should be enlighten for more and more applicability.
Evaluation of salivary cytokines in patients with fixed orthodontic treatment
Authors: Sharma Shaivi , Pamnani Meera
Published: April 2022

To evaluate the TNF-α and IL-1β levels in the gingival crevicular fluid (GCF) during orthodontic treatment. This study was carried out on 30 orthodontic patients. Prior to procedure, GCF was collected with a paper strip in gingival sulcus of maxillary right central incisor on the disto labial aspect for 60 seconds, followed by bonding and insertion of initial 14 NiTi archwire. GCF collection was repeated 24 hours, 7 days, and 30 days after bonding. Measurement of TNF-α and IL-1β levels was performed using Enzyme-Linked Immunosorbent Assay (ELISA). Data were evaluated statistically. There was raise in TNF-α and IL-1β concentration after treatment. There was no significant relationship between TNF-α and IL-1β concentrations subsequent to bonding in comparison to the baseline. There was no significant relationship in TNF-α and IL-1β level changes in the two age groups and among males and females. The present study indicated the raise in TNF-α and IL-1β concentration after treatment. There was no statically significant effect of gender and age on the concentration of TNF-α and IL-1β.
Feature extraction and classification based crop disease detection using deep neural network and ensemble convolutional neural network architecture
Authors: Kumar P. Dharmendra , Suhasini A.
Published: April 2022

Crop disease identification is crucial for avoiding production losses and lowering the amount of agricultural items produced. Machine learning-based approaches can be utilized to solve these types of problems. Deep Learning Techniques, which are commonly employed in image processing, have recently been involved in a number of agricultural applications. This research suggests detecting agricultural diseases using feature extraction and classifying those using deep learning algorithms. For the extraction of the segmented feature, we employ a pre-training model-based Deep Neural Network. The segmented feature will then be categorized using an ensemble classifier composed of Visual Geometry Group (19) and Inception V3++ architecture. This Ensemble Convolution Neural Networks (EN-CNN) classification will increase illness detection accuracy while minimizing time. Pre-trained Deep Convolution Neural Network (PDCNN) and EN-CNN are used to classify damaged and healthy leaves in a dataset of healthy and diseased leaves. The suggested model's resilience is empirically shown for crop disease detection in tomatoes and grapes. The suggested approach evaluated parameters with a 97 percent accuracy rate, a 98 percent precision rate, a 98 percent recall rate, and a 98 percent F-1 score rate.
Paraquat poisoning, what we should know
Authors: Manju B. , Jamal Sarfaraz , Lokesh N. K.
Published: April 2022

Paraquat (PQ) a brown syrupy liquid also known as methyl viologen is a commonly used herbicide in India. A highly toxic compound to humans, although, a large majority of fatalities from PQ poisoning are suicides. Accidental exposure is causing immense harm to farmers and agriculture workers, which is not documented.  Accidental or deliberate ingestion has an extremely high case-fatality rate, and clinical features are due to generating reactive oxygen species which cause cellular damage ultimately leading to multiorgan failure. At present there is no antidote to PQ poisoning, various treatment modalities from immunosuppressants to antioxidants are used with no clear clinical efficacy. Elimination methods such as haemodialysis and haemoperfusion when done early have shown to be useful in few studies. Recently drug-like Edaravone and Perfenidone are being used but with no survival benefit. Neither proper information nor training on the use of PQ and personal protective equipment are provided by agriculture offices to farmers leading to accidental exposure. Hence paraquat use has been restricted in many parts of the world and an appeal for a ban in India is underway as a need for preventive measures.
The socio-demographics and pattern of atherosclerosis of hos-pitalized adult patients without SARS-Cov-2 infection in a new tertiary hospital in Malaysia
Authors: Alati Mohamad Ahmad , Khalid Bahariah , Yusof Barakatun-Nisak Mohd , Appannah Geeta
Published: April 2022

Background: Atherosclerosis, a chronic inflammatory condition of the arterial intimal wall projected globally to impact healthcare significantly. The pattern of atherosclerosis, namely the atherosclerotic disease and atherosclerotic risk, may or may not be the reason for hospitalization; nevertheless, they have ongoing atherosclerosis that may progress over the years. Studies have shown that both patterns of atherosclerosis play an essential role in conferring poor prognosis and contributing to the leading cause of death. We embark on a study to analyze the socio-demographic and pattern of atherosclerosis of adult patients without SARS-Cov-2 infection admitted to a new tertiary hospital in Malaysia. We exclude patients who are predicted to have a high possibility of death or discharge within 24 hours, lactating mothers, oncology patients and non-Malaysian citizens; Methods: This prospective cross-sectional study recruited general medical and surgical ward adult patients between 9th October and 1st January 2021. The data were collected using face-to-face interviews with the patients and from the medical records. For our research, we identify the patient’s affirmation on having atherosclerosis, atherosclerotic disease, atherosclerotic risks, the reason for admission and their discharge outcome.
Neurological complications in COVID 19
Authors: Bakre Anand , Wanjari Anil , Aradhey Parag Rameshrao
Published: April 2022

Long term effects of COVID-19 are not known and more studiesare needed to understand effects of COVID-19 on the brain, which have already been observed. An investigation on the incidence and relative risk of neurological and mental disorders after a COVID-19 diagnosis was part of this research. We used data from the electronic well-being records network in this review partner investigation. On or after June1st, 2021, members of all partners experienced a list occasion and were still living on December 31st, 2021, disregarding maturation, at the end of the year. All patients who had a confirmed finding of COVID-19 were allocated in this study. Patients with flu and those with any respiratory illness, including flu, were included in the second group of controls.  The neurological symptoms were accessed and quantified according to the two groups and then statistically analysed for the significance. It was calculated that 82% of the 200 people identified with COVID-19 got a neurological or psychiatric diagnosis during the next six months.
Machine learning approaches for sentiment analysis
Authors: Monika P , Kulkarni Chaitanya , Harish Kumar N , Shruthi S , Vani V
Published: April 2022

Sentiment Analysis or Opinion Mining is popular task of Natural Language Processing (NLP) performed on textual data generated by users to know the orientation or sentiment of the text. To perform Sentiment Analysis, it is critical to create an accurate and precise model, machine learning techniques are heavily utilized to build an accurate model. Deep learning and transfer learning techniques have been found to have increased utilization and better results, making them one of the most popular research areas around the world. Hotel and restaurant industries analyze reviews to obtain a deeper understanding of their client’s needs, likes and dislikes, whereas specialists use Twitter data and stock market news items to forecast stock market trends. Machine Learning algorithms are most essential part of a Sentiment Analysis model, this survey paper analyze all the widely used Machine Learning Approaches for Sentiment Analysis. A brief introduction on Methodology for Sentiment Analysis is given along with conclusion and future scope and in the field of Sentiment Analysis.
A Study on Development of India in the Co existence of Populism and Liberalization of the Period 1990-2020.
Authors: Gayen Britya
Published: April 2022

India is a post-colonial democratic country. Its ideal is ideal of welfare state, as a major part of the people is marginal. Therefore, here much of modern politics is conditioned by the popular politics. It is not a new phenomenon across the globe. On the other hand, all countries irrespective of developed, developing or under developed are in the grip of liberalization, privatization and globalization (LPG). India is also not the exception to that phenomenon, although it is, in real sense, contrary to the populism. The wheel of liberalization has also been running in the world-largest democracy like India since 1991. But side by side, a lot of popular policies for welfare of the population has been taken by the government during the period from 1990 to 2020. Therefore, the paper has to highlight mainly the relationship between populism and development in terms of human development index (HDI) in the co-existence of the two opposite entities- populism and liberalization in India for the period- 1990-2020.
Consumers’ Perception towards Cashless Transactions and information Security in the Digital Economy
Authors: Mistry Chandra Bhan , Singh Dr. Mrs. Leena
Published: April 2022

" A cashless economy is an economic system in which there is little or very low cash flow in society and goods and services are purchased and paid the amount through electronic media. A cashless economy is an economy in which transactions are made by debit cards, credit cards, e-wallet, cheques, or direct transfers from one account to another through e-banking. According to the Government of India, cashless transactions will maximize employment opportunities in the economy, avoid cash-related robbery thereby minimizing the risk of carrying physical cash. Cashless transactions will also decrease cash-related corruption and attract more foreign investors to the country. The present study focuses on the concept and methods of cashless transactions in India. Besides, the study examines the benefits and limitations of a cashless economy to the general public."
Digital Payments During the Covid Pandemic.
Authors: Prasad Indu Shekhar , Samantha Dr. Amitava
Published: April 2022

" Digital Payments have been around the corner from a long time. Its adoption has been on gradual rise. Novel Corona virus resulted in new stage for digital payments. Social distancing, sanitization and safety emerged as new way of life. In this situation Digital Payment being contactless emerged as the preferred mode of payment. Local shoppers, vendors etc started to accept digital payments through barcodes and other means. Government including RBI also provided the suitable ecosystem to facilitate digital penetration. NPCI is also improvising its system to handle increased number of UPI transactions. This scenario drove the common people to try their hands at the digital payments. This pickup of digital payments is expected to continue."
A Review on Law Pertaining Protection and conservation and of the Environment and sustainable use of natural resources
Authors: Chakraborty Anita , Sharma Gopal , Singh J N
Published: April 2022

" Environment plays a vital role in the over-all well-being of human existence and their development. Protection and conservation of environment is the need of the hour. The need is also to ensure the sustainable utilization of the existing natural resources. The fact is also being strongly reflected in the constitutional framework of India as well as in India’s international commitments. Under Part IVA of constitution (Article 48A- Directive Principles of State Policies) stipulates that the State shall try to improve and protect the environment and safeguard forests and wildlife of the country. Furthermore, Part IVA of the Constitution also (Article 51A- Fundamental Duties), casts a duty on every citizen to improve and protect the nature and have compassion for all living beings. Since the 1970s, a number of environment legislations have been put forward. The apex administrative body in India i.e Ministry of Environment and Forest was established in year 1985. Today MoEF is responsible for regulating and ensuring environmental protection and lays down the legal and regulatory framework for the same. The present manuscript is an effort to review the Law pertaining protection and conservation of the environment and their sustainable utilization in India with special emphasis on State of Jharkhand."
Mediated Politics- The Amity of Politics and Media Houses
Authors: Sreenija Gopagani
Published: April 2022

News media is one among the most powerful tools of communication which plays a key role in building a nation’s strong, rational and healthy society by informing and empowering the citizens. It has the ability to shape the opinions and thoughts of the citizens and it is believed that the media has the power to make or break the Government. On the other hand, Politics has become a ‘power’ play where they use the tactics of Sam-Dhan-Bedh-Dhand to induce and persuade people in this democratic country to grab the administrative power. But when media shakes hand with politics for power instead of doing its duty, it becomes dangerously powerful making people pawns and democracy a joke in their power-play.
Examining the Concept of Existence from Aurobindo’s Point of View.
Authors: kela Richa
Published: April 2022

" Despite being the most evolved being among all other creations, human being hasn’t yet emerged as the best living being present on this planet earth. If we look at the process of evolution, nature of human has undergone various changes; from the archaeological evidence related to pre-humans, including Neanderthal, Cro-Magnon and of Neolithic age etc., to the modern evolution of human who is much more rational. However, this rationality has taken a distressing form in human beings as he has become more individualistic, and self-entered. Today, most of the people try to rule over something or other. These individualistic limitations have uplifted his egoistic nature which has lead world in the direction of disharmony. The researcher examining the concept of existence from Arvindo's point of view and will provide a new insight about concept of existence."
Role of Subjectivity in Preparation of Sampling Frames for Data collection.
Authors: Pathak Sadhan Kumar
Published: April 2022

"Collection of data from the field on various socio-economic aspects is consisting of several stages. Stratification of the population into required numbers of stratum (if it is heterogeneous) and the selection of sample units from each stratum on the basis of various random sampling method are precondition for scientific collection of data from a particular sample unit and therefore preparation of a scientific Sampling Frame which is the basis of selection of required number of sample units is of utmost importance. The established scientific procedure needs to be followed strictly while preparing the Sampling Frame and any subjectivity may enhance the sampling error to a great extent. An attempt has been made in this study to highlight the issues relating to the preparation of sampling frame in a Multistage Stratified Socio-Economic Survey and the role of subjectivity thereof."
Internal Branding: Exploring Market How to Sell Brand in the Internal Market?
Authors: Mishra Dr. Teena
Published: April 2022

" Internal branding is a vital component of internal marketing which improves organizational performance in the competitive era. Internal marketing creates employee orientation or internal customer orientation. This research paper focused on internal branding as a solution to improve the internal market, which has a positive impact on the external market, which leads to organizational success. This is a conceptual paper and data has been collected from various journals, books and online articles. In this globalization, liberalization and technological era, branding is the challenge facing the organization. Internal branding provides employees with information about the company's products and services, as well as an understanding of their value, which benefits customers. Customers respond positively to a customer-focused service culture. Internal marketing is concerned with employees; hence it develops employee orientation. Employees are aware of both tangible and intangible features of products and services that are provided to customers through internal branding. In this competitive era, attraction and retention are not the only ways to succeed. To sustain an organization in this competitive world, it is necessary to create a culture that fosters the best utilization of employees’ talent. Internal market orientation helps the development of employee brand knowledge."
Research and Teaching in Gedu College of Business Studies (GCBS): Does the interplay benefit the students?
Authors: Basu Mr Purnendu , Basu Dr Rupa , Peldon Mrs. Yeshi
Published: April 2022

" There is a long-standing question of whether there exist any nexus between Teaching and research or not. There is a strong argument that research and teaching should go side by side. For University Level teaching the faculty members must pursue research along with teaching. However, some studies pointed out that research and teaching have no linkage with each other. The key research objective is whether the faculty members perceive a relation to exist between the teaching and research, and does it, in their opinion, helping in delivering superior teaching to the students. The research approach adopted for the study is the qualitative research design. Information was collected by interviewing 45 faculties of the Gedu College of Business Studies (GCBS). The research unveils that although the faculties of GCBS are doing lots of research work, however, while teaching in the class faculties are opting for student-oriented teaching pedagogy. The research concludes that the research by the faculties in GCBS is not benefitting much to the student’s communities of the GCBS"
Edible Flora of Aquatic and Wetland Habitats of Varanasi District, Uttar Pradesh
Authors: Pandey Ravindra , Pandey Chetna
Published: April 2022

The present contribution deals with the food value of aquatic and wetland plants of Varanasi district. During study 54 plant species belonging to 43 genera and 31 families were found to be useful for their food value. Most of the plants of these habitats were found to be useful for vegetables. Largest family recorded was Poaceae with six species useful to provide food grains. Certain plants were found to be useful for their edible fruits, seeds, salad, pot-herb, curry and as mouth freshener.
Some interesting indigenous beverages among the Primitive Tribal groups of Visakhapatnam district, Andhra Pradesh
Authors: Rao J. , Manikyam P. , Reddi T.V.V.
Published: April 2022

The present paper deals with 11 beverages viz., rice beer, liquor from rice, ragi beer, banana liquor, jack fruit liquor, jaggery liquor, marking nut liquor, panicum beer, mango beer, Caryota toddy, and sorghum liquor brewed by the Primitive Tribal Groups of Visakhapatnam district along with their methods of preparation.
Metathelypteris Flaccida (Blume) Ching (Thelypteridaceae: Pteridophyta), A Very Rare and little known fern from Kerala
Authors: Antony Raju , Mohanan N.
Published: April 2022

Metathelypteris flaccida (Blume) Ching, a very rare and little known ‘thelypteroid’ fern is collected after Beddome (1883) from Kerala. A detailed description and photographs are provided for its easy identification.
Cistoadenoma Seroso del Epidídimo.
Authors: Granados Loarca Edgar Antonio , Muñoz Luis Fernando , Calderón Pacheco Gylari , Morales Hesler
Published: April 2022

Objetivo: Reportar un caso de tumor paratesticular, Cistoadenoma Seroso del Epidídimo. Entidad de rara aparición.

Métodos/Resultados: Reportamos un caso de un paciente varón de 60 años que acudió con una masa paratesticular en el escroto izquierdo, en el que la histología reporto un cistoadenoma seroso del epidídimo, tumor epitelial benigno poco frecuente, relacionado con hidrocele, descenso de niveles de testosterona y disfunción eréctil.   El tratamiento fue la exéresis quirúrgica y la administración de testosterona intramuscular.

Conclusiones: Estos tipos de tumores suelen acompañarse de hidrocele, ante el hallazgo de una hidrocele + masa paratesticular debe de realizarse un buen examen físico y usar el ultrasonido como medio de diagnóstico por imagen, y efectuar la exéresis de la hidrocele y de la masa del epidídimo para evitar orquidectomias innecesarias, a menos que infiltren el testículo.
Caso Clínico. Condiloma Acuminado.
Authors: Morales Ruiz Mario , Lezana Juan Pablo , Hernández Víctor , Montejo Mario , Carrillo Nestor , López Fredy
Published: April 2022

Son un tipo de lesiones a nivel genital, ásperas y duras con un aspecto de coliflor, suelen estar acompañados de hidrocele más una masa paratesticular o epididimaria.
Caso Clínico. Seminoma.
Authors: Morales Ruiz Mario , Lezana Juan Pablo , Hernández Víctor , Montejo Mario , Carrillo Nestor , López Fredy
Published: April 2022

Paciente masculino, acude con historia de masa en cuello de 5 meses de evolución, con presencia de tumoración supraclavicular izquierda, dura, no móvil, superficie irregular, dolorosa a la palpación.
Caso Clínico: Fractura Penena.
Authors: Morales Ruiz Mario , Lezana Juan Pablo , Hernández Víctor , Montejo Mario , Carrillo Nestor , López Fredy
Published: April 2022

Paciente masculino con Hematoma peneano de 4 horas de evolución, que previo a su ingreso tuvo relaciones sexuales con su pareja, de una manera enérgica, al momento de la penetración, el pene se «tuerce» y escucha un chasquido en el mismo, inmediatamente pierde la erección asociada a dolor peneano, presenta dolor y hematoma en pene.
Artículo en Revisión. Caracterización de Cáncer Testicular Hospital General San Juan de Dios, Enero de 2014 a Junio de 2015.
Authors: Carrillo Néstor F. , Estrada Manuel , Montejo Mario , Morales Mario Roberto
Published: April 2022

Introducción: Los tumores testiculares presentan características morfológicas y manifestaciones clínicas diversas, el 95% corresponde a tumores de células germinales, se suelen clasificar en seminoma y no seminoma, representan el 1 a 2% de los canceres en el hombre.

Objetivo: Caracterizar el cáncer testicular en nuestra población, en base a su frecuencia, edad de presentación, tipo histológico, síntomas de presentación, para poder conocer a que nos enfrentamos al evaluar a estos pacientes.

Métodos: Recopilación de datos directos del expediente clínico de 23 pacientes que fueron intervenidos por Orquidectomía radical en el periodo de enero de 2014 a junio de 2015 en el Hospital General San Juan de Dios.

Resultados: se evaluaron un total de 23 pacientes con diagnóstico de tumor testicular, la mayor incidencia se dio en pacientes comprendidos en la edad de 21-40 años (52.7%), el síntoma o signo mayormente presentado fue la masa testicular palpable (82%), el tiempo de evolución de la enfermedad antes de la consulta fue menor a 6 meses, todos los pacientes fueron sometidos a Orquidectomía radical, el diagnóstico patológico más frecuente fue de seminoma puro con 10 pacientes (43.47%),  del total de pacientes, 15 presentaron el marcador tumoral hCG β elevada, 4 presentaron AFP elevada, con el 80% de pacientes residentes de la ciudad capital, y en 17 pacientes el teste afectado correspondió al izquierdo (75%), el 82% de los pacientes recibió quimioterapia después del tratamiento quirúrgico, no se reportó ningún deceso en la revisión.

Conclusión: el tumor testicular es una causa importante de morbilidad en los varones, sobre todo los no diagnosticados a tiempo, sin embargo la mortalidad en nuestro centro es nula o igual a 0, se recomienda siempre el autoexamen en los varones y consultar por cualquier manifestación que no sea normal a nivel genital.
Hiperplasia Prostática Gigante Tratada por Prostatectomía Transvesical.
Authors: Arriaga Morales Hugo Roberto , Figueroa Lemus Carlos Francisco , Vela M. Roberto Alejandro
Published: April 2022

Reportamos un caso de Hiperplasia Prostática Gigante tratada por Prostatectomía Transvesical. Paciente de 68 años presentó historia de síntomas urinarios obstructivos bajos. Se realizó Tomografía de Abdomen completo visualizando próstata con peso calculado mayor a 500 gr. El valor del antígeno prostático especifico estaba en 4.021 ng/ml. Realizamos Prostatectomía abierta a través de la vejiga. El adenoma fue removido en una pieza, pesando 470 gramos. El examen histopatológico reveló Hiperplasia Nodular Prostática Glandular. La cirugía abierta es el tratamiento recomendado para este tipo de patología prostática, sin embargo, nuevas opciones quirúrgicas, como la enucleación endoscópica, podrán ser viables para los pacientes en el futuro.
Reporte de Caso Reflujo Vesicoureteral Bilateral Grado V con Inserción Parauretral.
Authors: Maldonado Berducido Oscar Maldonado , Pérez Chun Sergio Guillermo , Salazar Monterroso Carlos Brisbane , Petersen Juárez Erick Stanley
Published: April 2022

El reflujo vesicoureteral tiene una variabilidad distinta y resolución espontanea cuando son grados I – III sin embargo grado IV – V ameritan resolución quirúrgica. La prevalencia de reflujo es cerca de 30% en paciente con infección urinaria y 17% sin ella. Un 25 % se presenta en niñas mayores de 4 años. Se presenta caso de un paciente de sexo femenino de 4 años con reflujo vesicoureteral grado V bilateral con inserción parauretral, manejado en el servicio de Urología del Instituto Guatemalteco de Seguridad Social.
Reporte de Caso Carcinomas Renales Menos Frecuentes: Carcinoma de Ductos Colectores (Carcinoma de Bellini).
Authors: Mansilla Guillén Edgar Alfredo , Pérez Chun Sergio Guillermo , Salazar Monterroso Carlos Brisbane , Petersen Juárez Erick Stanley
Published: April 2022

Los estudios morfológicos detallados y las técnicas moleculares contemporáneas y de inmunohistoquímica han resultado en las nuevas clasificaciones de neoplasias epiteliales renales. El carcinoma renal de células claras, papilar y células cromófobas 85 – 90% de neoplasias renales malignas. El restante 10 – 15%, esporádicos, familiares y poco comunes. El carcinoma de conductos colectores de Bellini representa un tipo raro de malignidad menor del 1%. Frecuentemente se presenta en estadíos avanzados, reportado desde la 3era. a 5ta. década de vida, 40 – 50% presenta metástasis al momento del diagnóstico, y tiene una expectativa de vida de 1 a 3 años después de su diagnóstico. Se presenta el caso de un paciente de sexo masculino de 46 años de edad manejado en el servicio de urología del Instituto Guatemalteco de Seguridad Social con diagnóstico patológico de Carcinoma de conductos colectores de Bellini.
Reporte de Caso Liposarcoma de Cordón Espermático Introducción.
Authors: Arriola Ortíz Hugo Aaron , Pérez Chun Sergio Guillermo , Salazar Monterroso Carlos Brisbane , Petersen Juárez Erick Stanley
Published: April 2022

Los liposarcomas representan solamente el 2 % de los tumores de cordón espermático. Siendo así este caso de suma  importancia ya que no es frecuente. Liposarcoma, es el subtipo histológico más habitual en adultos.  Se clasifican en: bien diferenciado “lipoma like”, mixoide más células redondas, pleomórfico y desdiferenciado. Sus metástasis son infrecuentes, más su recidiva es local.  Su tratamiento es la orquiectomía más ligadura alta del cordón. La radioterapia solamente se recomienda en presencia de metástasis o de extirpación local inadecuada. Se presenta caso de paciente de 71 años manejado en el instituto guatemalteco de seguridad social a quien se le diagnostica por patología liposarcoma paratesticular izquierdo.
Resumen de Guatemala Nefrectomía Laparoscópica Asistida de Donante Vivo para Trasplante Renal. Experiencia en el Hospital General de Enfermedades, Instituto Guatemalteco de Seguridad Social.
Authors: Aguilar Salguero Francisco Ángel Antonio , Petersen Juárez Erick Stanley , Polanco Gudiel Estuardo José
Published: April 2022

Los procedimientos quirúrgicos laparoscópicos son una alternativa razonable a los procedimientos abiertos en diversas patologías urológicas, los cuales, incorporados paulatinamente, hacen la diferencia ante una terapia mínimamente invasiva. Los casos presentados evidencian las ventajas sobre la cirugía abierta como menor tiempo de hospitalización, menos dolor postoperatorio, incorporación laboral temprana, mejor estética y promueven la donación renal.
Resumen de Panamá. Comparación del Puntaje de Gleason de la Biopsia Transrectal de Próstata y el Espécimen Quirúrgico de Prostatectomía Radical en Pacientes del Complejo Hospitalario Metropolitano Dr Arnulfo Arias Madrid. Mayo de 2015-Mayo 2016.
Authors: Sanchiz . , Figueroa . , Jiménez . , Alston .
Published: April 2022

Según estadísticas del Ministerio de salud el cáncer de próstata es el de mayor incidencia y la primera causa de muerte por tumores malignos en los hombres panameños.

La escala de Gleason se asocia con el riesgo de sobrevida cáncer específico en pacientes llevados a tratamiento definitivo o conservador, así como con el riesgo de progresión bioquímica y metástasis. Desafortunadamente el examen patológico del espécimen quirúrgico a veces revela que los tumores tienen mayor extensión de lo que predice el estadio clínico y los reportes del puntaje de Gleason de la biopsia no siempre concuerdan con los definitivos obtenidos de la prostatectomía radical.
Resumen de El Salvador. Sarcoma de Ewing/Tumor Neuroectodérmico Renal Primario. Reporte de Caso.
Authors: Mejía Beltrán Marvin Alfredo , Pleitez Herbert Armando , Fuentes Alex , Cruz Julia Beatriz , Medrano Emilio , Díaz Nelson
Published: April 2022

Entre los tumores renales de pequeñas células redondas se encuentra el sarcoma de Ewing también llamado tumor neuroectodérmico periférico primitivo; la cual es una entidad rara con un curso clínico sumamente agresivo.

Los sarcomas renales primarios son tumores raros, que se da en niños y en jóvenes adultos, a una edad media de 28 años y con una predominancia ligeramente mayor en hombres, se han reportado alrededor de 100 casos en la literatura.

Los pacientes permanecen asintomáticos hasta que el tumor alcanza gran tamaño, cuyos síntomas más frecuentes incluyen dolor abdominal/flanco, masa palpable, hematuria.

Los síntomas sistémicos incluyen: pérdida de peso, y fiebre; el pronóstico es pobre con una supervivencia global baja.

Su tendencia es extremamente agresiva y se caracteriza por dar metástasis en forma temprana en un 25-50% de los casos con metástasis a pulmón, hígado y hueso.
Tumor Germinal Retroperitoneal Extra Gonadal A propósito de un caso.
Authors: Maldonado Berducido Oscar Humberto , Petersen Juárez Erick Stanley , Salazar Monterroso Carlos Brisbane , Pérez Chun Sergio Guillermo
Published: April 2022

Los tumores testiculares representan aproximadamente 1% de todos los tumores malignos en hombres. Es el tumor más común en el grupo etario de 15 a 35 años. (1,2,3,4). Los tumores extragonadales de células germinales  son raros, cerca 2 a 5 %, de los cuales el 60% corresponden  seminomas, se ubican con frecuencia en diferentes lugares como ejemplo mediastino, retroperitoneo, glándula pineal, hígado, vejiga, hueso, próstata, estomago. El origen de los mismos todavía es motivo de discusión, existen dos teorías en las cuales se considera que pueden originarse de células totipotenciales, o de una migración anormal de las células germinales primordiales. (2,3,5,)

Paciente masculino de 34 años, quien consulto por historia de dolor abdominal(,) por lo que médico particular le realiza ultrasonografía abdominal la cual reporta masa renal derecha, por lo que es ingresado al Instituto Guatemalteco de Seguridad Social en donde se  realiza  urotomografía(,) la cual reporta masa renal derecha. Se lleva a sala de operaciones para realizar nefrectomía Radical derecha más tumorectomía  del 80%, identificando por patología y pruebas de inmunohistoquimica que corresponde a seminoma. Se realiza marcadores tumorales con resultados en límites normales. Se realiza ultrasonografía testicular en donde se identifica testículo izquierdo atrófico, con imagen heterogénea. Se da seguimiento por oncología médica iniciando tratamiento con quimioterapia.
Como Protegerse de los Litigios en la Práctica Médica.
Authors: Granados Loarca Edgar Antonio
Published: April 2022

En Guatemala, cada día aumenta el riesgo de que los médicos independientemente de la especialidad médica que tengan, puedan caer en lo que se conoce como mala práctica. Ya sea que se trabaje solo en lo privado, en lo privado e institucional y solo en alguna Institución. Se pretende en este Editorial dar a conocer más sobre este tema a los médicos Urólogos como darles a conocer algunos principios para evitar ser demandado por esta causa.
Retención Urinaria.
Authors: Arriaga Morles Hugo Roberto , Vela Mollinedo Alejandro
Published: April 2022

Retención urinaria es un término que se utiliza para describir la situación en la cual la vejiga no puede ser vaciada completamente o no se vacía del todo. Puede presentarse de forma aguda, crónica y agudizarse la presentación crónica. La retención urinaria aguda (RAO) es una emergencia urológica común, caracterizada por la incapacidad de evacuar orina acompañada en algunos casos de dolor.
Nefrolitotomia Mini- Percutánea, Experiencia Inicial en Hospital Privado Centro Médico, Ciudad de Guatemala.
Authors: Barbales Hugo Roberto , Ríos Sierra Gilberto , Méndez Cruz Guillermo
Published: April 2022

La nefrolitotomía mini percutánea (NLP mini perc) se considera una evolución menos invasiva que la nefrolitotomia percutánea (NLPC) tradicional, en ella se utilizan trayectos de dilatación menores a 18 Fr. Esto permite menor daño al parénquima renal con menor índice de complicaciones y la posibilidad de realizarla sin utilizar tubos de drenaje (nefrostomia y catéter doble J).  Los objetivos como cualquier procedimiento son dejar una tasa libre de cálculos en un solo tiempo quirúrgico, con las ventajas de la técnica miniinvasiva. Presentamos la experiencia inicial en nuestra práctica Privada de NLP mini perc en casos seleccionados para esta técnica.
Neoplasia Renal Poco Frecuente en un Paciente Joven Carcinoma Renal de Conductos Colectores.
Authors: Arriola Ortíz Hugo Aaron , Petersen Juárez Erick Stanley , Polanco Gudiel Estuardo José , Salazar Monterroso Carlos Brisbane , Pérez Chún Sergio Guillermo , Monterroso Julio , Orozco Roberto , Grajamo Marisol , Fortuny Alina
Published: April 2022

El cáncer renal constituye alrededor de 3% de las neoplasias malignas 1,2,6,7,8,10. La relación por sexo es mayor en el género masculino, con una relación 3:2 1,2,8,10. Es la neoplasia de vía urinaria de mayor mortalidad, que es alrededor de 40% 1,5,8,10. Solamente en un 3% a 8% se diagnostican en pacientes menores de 40 años, según diferentes estudios 1,3,8,10. Los factores pronósticos conocidos son: el estadio clínico, el grado celular y el tipo histológico 1,4,8,9,10. Algunas series han señalado que los pacientes de menor edad se ha encontrado presencia de metástasis y afección linfática, según el comportamiento biológico es más agresivo en pacientes jóvenes 1,4,8,10. El diagnóstico incidental en pacientes menores, es mayor por el recurso de la ultrasonografía y de tomografía, con ello es factible que se diagnostiquen en un estadio clínico temprano mejorando las posibilidades de sobrevida 1,7,8,10. Además, el carcinoma de conductos colectores representa del 1 al 3% de las neoplasias renales, presentando en un 45% metástasis al momento de su diagnóstico y presentando una sobrevida de 12 a 36 meses 1,8,9,10.   Se presenta caso de paciente de 23 años manejado en el Instituto Guatemalteco de Seguridad Social a quien se le diagnostica por patología Carcinoma Renal de Conductos Colectores del lado Derecho.
Reporte de un Caso. Cáncer Testicular de Senos Endodérmicos en Lactante.
Authors: Brañas Jurado Javier Alejandro , Petersen Juárez Erick Stanley , Salazar Monterroso Carlos Brisbane , Pérez Chun Sergio Guillermo , Orozco Roberto , Grajamo Marisol , Fortuny Alina
Published: April 2022

Se presenta caso poco frecuente en paciente de sexo masculino de 1 año y 2 meses, que inicia con aumento de volumen de testículo izquierdo, el cual se diagnóstica por ultrasonido con presencia de masa testicular izquierda, por lo que fue llevado a sala de operaciones para orquiectomía radical. En estudios posteriores anatomopatológicos reportan neoplasia testicular de senos endodérmicos.

Las neoplasias testiculares de células germinales son derivados de células germinales primordiales, las cuales en inicios de la vida embrionaria realizan migración desde el sistema nervioso central primitivo hasta su localización posterior a nivel de las gónadas.  Son tumores de causa desconocida y representan el 95% de tumores testiculares.1 Estos también son conocidos como carcinoma embrionario infantil o del saco vitelino, se presentan con mayor frecuencia en lactantes y niños hasta los 3 años y con mucho menor frecuencia hasta los 5 años, tienen una incidencia de 6 por cada 100,000, en varones y con predominio en raza blanca (relación 5:1).2 Para su diagnóstico se debe de tomar en cuenta los aspectos: clínico, que se realiza con el hallazgo de una masa testicular o intraescrotal sólida, principalmente sin presencia de dolor y de consistencia firme, bien definida y móvil a la palpación; sérico con la realización y determinación de pruebas de alfa feto proteína, hormona gonadotropina coriónica y lactato deshidrogenasa, de suma importancia para nuestra valoración pronóstica y respuesta al tratamiento establecido; radiológico, el estudio principal de mucha utilidad es el ultrasonido que nos permite valorar dimensiones del testículo y de la tumoración, así como características del testículo contralateral; los estudios tomográficos de pelvis y tórax son de apoyo para clasificar su estadiaje y valorar tratamiento; por último, histológico, la confirmación del tumor se da por resultado de patología. La literatura reporta rango de sobrevivencia que se relaciona con la edad, sin embargo, hay rangos de sobrevivencia del 96% posteriores a la quimioterapia. Este tipo de neoplasias de células germinales son de tipo muy agresivo y capaces de producir metástasis extensas; sin embargo, por los avances científicos y la evolución en los tratamientos médicos, el pronóstico ha mejorado debido a su manejo multidisciplinario
Analysis of Students' Critical Thinking Skills in Solving Trigonometric Problems
Authors: Sianturi Roland , Astrilia Putri
Published: April 2022

The thought processes practiced in school are limited to cognition, memory, and convergent thinking, while divergent thinking and evaluation are less noticed. Learning activities focused on recording, memorizing, and recalling, learning is concentrated on exercises that are procedural and mechanistic. This research aims to find out the critical thinking skills of students in solving trigonometric problems in grade XI of SMA Negeri 6 Medan. The type of research used is qualitative descriptive. The subjects in this study amounted to 1 person who was selected using the purposive sampling technique, which is the highest score of student test results. The instruments used are tests to find out the student's learning results as the basis for subject selection and interviews are used to find out the student's critical thinking skills. Data analysis used is qualitative data analysis consisting of data reduction, data presentation, and conclusion withdrawal. The results of data analysis obtained that the subject in the learning process and the process of solving the problem of trigonometric material has the ability to think critically. Subjects have three indicators of critical thinking skills used in this study, namely trying to know information well, providing reasons for problem solving, and looking for alternative solutions
Analysis of Students' Mathematical Concept Representation Ability in Solving Space Building Questions
Authors: Kamsurya Marwa Astriani
Published: April 2022

The purpose of this study is to describe the ability to represent the mathematical concept of students in solving spatial building problems. The type of research used is qualitative descriptive. Data is collected using tests, interviews, and documentation. Tests and interviews are conducted to learn more about the ability to represent the mathematical concept of students in solving the problem of building a room. The subjects in this study were two people, obtained from 30 students through a test of subject networking. The results of the data analysis showed that the ability to representation of mathematical concepts of students arises when presented mathematical problems, namely visual ability, symbolic ability and verbal ability. Visual capabilities in the form of images are to create geometric building images to explain problems and facilitate their resolution; symbolic ability in the form of mathematical equations or expressions by creating mathematical equations or models of the given representation and problem solving by involving mathematical expressions; verbal ability in the form of written words or text that is to write the interpretation of a representation appropriately and write down the steps of solving mathematical problems
Scabies Among Health Care Workers in Sarhad Psychiatric Hospital Peshawar Khyber Pakhtunkhwa
Authors: Afzal Muhammad , Faridi Tallat Anwar
Published: April 2022

Scabies is a neglected parasitic disease but of great importance in developing countries. It is endemic in tropic and sub-tropical countries. It is caused by a mite and transmitted through skin-to-skin contact  Objective: The study will provide a better opportunity to adopt protective measures and thus reduce the disease burden in hospitalized patients Method: The aim of my study is to assess the scabies level of health care workers at Sarhad Hospital for Psychiatric diseases Peshawar regarding scabies. In our study, the respondents were doctors, Nurses, and junior clinical technicians of both sexes. Result: Rather than this, no such studies have been conducted in Pakistan. There have been some reported studies in different countries where an outbreak of scabies has been reported. Where health workers were also been affected as well as patients. Conclusion: Scabies outbreaks occur due to poor personal hygiene, poor environmental sanitation, low socioeconomic conditions, lack of basic healthcare facilities, over-crowding and illiteracy.
Molecular Exploration of Zinc Finger BED-Type Containing 6 Gene for Growth Trait in Beetal Goat
Authors: Rashid Kanwal , Javed Maryam
Published: April 2022

Zinc finger, BED-type containing 6 (ZBED6) is a newly discovered transcription factor. It functions as a repressor of IGF2 transcription in skeletal muscle myogenesis and development. It plays a role in organism development, signaling, cell-cell contact, hepatic fibrosis, clathrin-mediated endocytosis, and tight junction signaling cascades. Using C2C12 cells, chromatin immunoprecipitation (ChIP) sequencing revealed roughly 2,500 ZBED6 binding sites in the genome, with the inferred consensus motif matching the known binding site in Igf2. Igf2 expression, cell proliferation, wound healing, and myotube formation is all affected when Zbed6 is silenced in myoblast cells. Certain Gene Ontology categories, such as development and transcriptional control, were significantly enriched in genes related to ZBED6 binding sites. Objective: To explore the molecular expression of the ZBED6 gene  that affect the growth trait in Beetal goat Methods: The BED6 gene's functional and signaling experiments revealed that it controls growth characteristics in goats. A total of 50 blood samples were taken. DNA was extracted using an inorganic technique. Primer3 software was used to build primers for PCR amplification. On the ABI 3130XL Genet Analyzer, PCR results were sequenced bi-directionally. Results: The CHROMAS program was used to examine the sequencing findings. SNPs were discovered using sequence alignment tools such as blast 2. The bovine ZBED6 gene was found on chromosome 16, has only one exon, and encodes 980 amino acids. The genomic DNA of both cow breeds was effectively amplified in this investigation by utilizing primer pairs for the ZBED6 gene. These animals had three SNPs, including one non-coding mutation in the promoter (SNP1: 826G > A) and two missense mutations in the CDS (SNP2: 680C > G and SNP3: 1043A > G). The missense mutations p. Ala 227 Gly and p. His 3" are found in SNP2 and 3. Conclusions: Novel variations have been discovered that might be used in the selection of superior goats with higher weight increase tendencies.