bluuebunny/crossref_metadata_2025 huggingface dataset:
Kaedah Pemikiran Kritis al-Dihlawi terhadap Perbahasan al-Sa’adah (Kebahagiaan) dalam Karya Hujjah Allah al-Balighah
Authors:   Akademi Pengajian Islam Kontemporari, Universiti Teknologi MARA (UiTM) Cawangan Kelantan, Kelantan, Malaysia, Junoh Noraini , Mustafa@Busu Zanirah ,   Akademi Pengajian Islam Kontemporari, Universiti Teknologi MARA (UiTM) Cawangan Kelantan, Kelantan, Malaysia, Mohamad Abdul Manam ,   Jabatan Pengajian Ilmu Wahyu dan Pemikiran Islam, Fakulti Pengajian Umum dan Pendidikan Lanjutan, Universiti Sultan Zainal Abidin, Terengganu, Malaysia
Published: August 2024

Era ini menyaksikan dunia yang berkembang dengan begitu pantas sehingga berlaku ketidakpastian dan kecelaruan pemikiran. Gagasan kemodenan yang dicanangkan oleh Barat telah melahirkan pemikiran-pemikiran yang bertentangan dengan akidah Islam sehingga menolak keautoritian al-Quran dan Sunah. Dalam kepesatan teknologi kini juga, umat Islam dilihat perlu menyesuaikan kehidupan mereka dengan gaya hidup moden walaupun bersalahan dengan ajaran Islam. Kajian ini bertujuan untuk menganalisis kaedah pemikiran kritis al-Dihlawi berdasarkan perbahasan al-sa’adah (kebahagiaan) dalam kitab Hujjah Allah al-Balighah. Kajian ini menggunakan kaedah kualitatif. Sorotan pembacaan secara mendalam telah dilakukan terhadap kitab Hujjah Allah al-Balighah sebagai sumber utama. Penterjemahan teks merupakan langkah pertama diikuti kaedah analisis kandungan bagi mengekstrak konsep kebahagiaan yang dikupas oleh al-Dihlawi dalam konteks kaedah pemikiran kritis. Hasil analisis mendapati terdapat lima kaedah pemikiran kritis al-Dihlawi yang digunakan dalam membahaskan al-sa’adah, iaitu pemikiran soal jawab, rasional, saintifik, kesufian dan rabbani. Dengan kaedah ini, umat Islam dapat memantapkan minda dan pemikiran dalam mencapai kebahagiaan hidup di dunia dan akhirat. Kebahagiaan bermula ketika akal manusia dapat menguasai nafsu dan menolak perkara bertentangan dengan wahyu. Pemikiran kritis mengupayakan manusia untuk membezakan antara yang benar dengan yang batil melalui panduan wahyu. Ketika seseorang telah menguasai nafsunya dan memiliki sifat ketaatan yang tinggi, maka dia dapat mendekatkan diri kepada Allah SWT dan memperoleh keberkatan-Nya.
Nutrigenomics and Gene Modulation Associated with Cardiovascular Diseases
Authors: Mello Priscila Gomes de , Albuquerque Eliane Papa Ambrosio
Published: August 2024

Introduction: Cardiovascular diseases (CVD) are responsible for 31% of global mortality, most in the form of coronary heart disease (CHD) and stroke. Nutrigenomics and nutrigenetics have been tools in the prevention and treatment of cardiovascular diseases. Objective: to review the main polymorphisms related to food metabolism that can be used in the diagnosis and monitoring of cardiovascular diseases. Material and Methods: This study is qualitative and descriptive through a literature review that consulted the PubMed, Virtual Health Library, Scielo, Capes Portal and Google Scholar databases with original articles published in Portuguese and English in the period between January 2010 and September 2021. Results: 26 articles were found as potentially in accordance with the search criteria. After analyzing the abstracts, 17 articles (65.38%) were excluded and 10 (38.46%) articles were selected. Discussion: Benefits of changing the dietary pattern were found that can promote prevention and reduce the risk of cardiovascular events. Conclusion: The use of bioactive substances can contribute positively to modulating the expression of genes associated with increased cardiovascular risk.
Program Literacy Status of Special Education Teachers
Authors: Göl Hakan , Ergün Naif
Published: August 2024

Introduction: Special education curricula are different from other curricula. For special education teachers to be able to prepare and implement individualized education programs for their students, it is important for them to know and understand the curricula at special education level and to have curriculum literacy. Accordingly, the purpose of this study is to examine the relationship between curriculum literacy, self-efficacy beliefs and curriculum commitment levels of special education teachers. In addition, the study also analyzed how teachers' curriculum literacy, self-efficacy beliefs and curriculum commitment levels change according to various demographic variables. Method: In this study, we used a descriptive-correlational research model. We obtained the research data using scales developed for this purpose. We collected data from 402 (female: 213, male: 189) special education teachers in different geographical regions of Turkey and analyzed it using the Statistical Package for Social Sciences (SPSS) 26 data analysis program. Findings: The study found that special education teachers had good levels of curriculum literacy, self-efficacy beliefs, and commitment to the curriculum. The results showed that curriculum literacy and self-efficacy belief levels did not differ according to gender, while the level of commitment to the curriculum differed in favor of women. The findings indicated that the level of curriculum literacy and curriculum commitment did not differ according to educational status, while the level of self-efficacy beliefs differed in favor of teachers with graduate degrees. Program literacy, self-efficacy belief, and program commitment levels differed significantly according to the field of graduation. The analysis revealed that curriculum literacy, self-efficacy beliefs, and curriculum commitment levels were highly correlated with each other. Finally, the study determined that teacher self-efficacy beliefs and curriculum commitment levels were predictors of curriculum literacy. Discussion: According to the findings, we concluded that special education teachers have high levels of curriculum literacy, curriculum commitment, and self-efficacy beliefs, and we presented recommendations in this context.
A Novel Nanocomposite Based on (Zea mays) Corn Cob Biochar and Maghemite for the Competitive Adsorption of Endocrine Disruptor Compounds
Authors: S. Cardoso Carolina , da Silva Mayara , Saatkamp Rodrigo Henrique , B. Caon Natália , Valentini Giuliana , Luis Parize Alexandre , Vitali Luciano
Published: August 2024

Faced with the global challenge of water treatment, the investigation of the removal of endocrine disruptor compounds (EDCs) in aquatic environments is essential to protect human and animals health. In this study, a novel nanocomposite was prepared from biochar from agricultural waste (corn cob) and maghemite (γ-Fe2O3) nanoparticles, named PCCN, to remove four EDCs (triclosan, 17α-ethinylestradiol, methylparaben, and bisphenol A) from aqueous solutions by adsorption. For the characterization of PCCN, the advanced techniques Fourier transform infrared spectroscopy (FTIR), Brunauer-Emmett-Teller analysis (BET), pH of point of zero charge (pHpzc), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetry (TGA) were employed. Competitive adsorption equilibrium studies of EDCs were performed with PCCN and compared to unmodified biochar (PCC). The pH effect showed that optimal adsorption of EDCs was at pH 8.0 for PCC and pH 6.0 for PCCN. The salt concentration did not influence EDCs in the adsorption. In the adsorption isotherm, the results fitted the Freundlich isotherm model (R2 > 0.903) and the adsorption kinetics were well described by the pseudo-second-order model (R2 > 0.985). Furthermore, the desorption studies indicated that the PCCN can be reused. Thus, the investigation suggests PCCN has promising potential in the removal of EDCs from wastewater.
Evaluation of Thermodynamic Properties and Antioxidant Activities of an Adsorbent-Bioactive Complex with Antioxidant Characteristics
Authors: M. da Silva Neto José , S. C. Oliveira Líbia , P. de Gusmão Rennan , S. Lima Fernanda
Published: August 2024

Jaboticaba peel powder (JPP) is a residue that contains phenolic compounds, such as anthocyanins and gallic acid. An adsorbent-bioactive complex (ABC) was synthesized using an extract rich in compounds with antioxidant properties obtained from JPP immobilized on microcrystalline cellulose from sweet sorghum bagasse. In this work, the result of thermal degradation of anthocyanins from JPP and ABC, activation energy (Ea), half-life time (t1/2), decimal reduction time (D), temperature variation (Z), thermodynamic parameters (enthalpy (ΔH), Gibbs free energy (ΔG) and entropy (ΔS)) and degradation of antioxidant activities were investigated. Anthocyanin degradation of 35, 60 and 85% was observed for JPP and 10, 30 and 65% for ABC at temperatures of 90-130 °C. Ea of JPP and ABC were 110 and 91 kJ mol-1, respectively. ABC was able to increase from 143-690% the half-life time when compared to JPP. The Z parameter indicated that a greater temperature variation is necessary to degrade ABC anthocyanins (31 °C) when compared to JPP (25 °C). The thermodynamic parameters showed that the energy needed to be broken down to reach the transition state is higher for JPP than ABC, in addition ABC is closer to its thermodynamic equilibrium state. Thus, ABC can be used as an additive in pharmaceutical, cosmetics and food industries, maintaining bioactive and antioxidant properties.
Antibiotic resistance ofE. coliisolates from different water sources in Mbarara, Uganda
Authors: Catherine N. Abaasa , Claudia Stange , Savino Ayesiga , Edgar Mulogo M. , Rogers Kalyetsi , Julius Lejju B. , Morgan Andama , Imelda Tamwesigire K. , Joel Bazira , Frederick Byarugaba , Andreas Tiehm
Published: August 2024

Escherichia coli is widely used as an indicator of recent faecal pollution of water. Most E. coli strains are commensals; however, isolates in water samples have been shown to carry antibiotic resistance determinants. In total, 47 E. coli were isolated from selected drinking water sources in Mbarara, Uganda. The isolates were examined for their susceptibility to seven antibiotics and the presence of nine antibiotic-resistance genes (mostly β-lactamase genes) and class 1 integrons. Isolates showed a high resistance to ampicillin of 55.5% and a high sensitivity to azithromycin and gentamicin at 98 and 96%, respectively. PCR analysis showed the presence of extended-spectrum β-lactamase genes blaCTX-M-32 and blaCMY-2 in 64 and 36% of the isolates. The carbapenemase genes blaOXA-48, blaVIM-2, blaNDM-1, and blaKPC-3 were either not detected or only in a very small number of the isolates, whereas class 1 integrons were present in 68% of the isolates. This study proves that antimicrobial resistance exists in E. coli in water used for drinking purposes in Mbarara city. There is a need for public health actors to improve the surveillance of microbiological quality of drinking water to minimize health risks.
Graphene: Understanding its Structure, Synthesis, and Functionalization
Authors: Punetha Vinay Deep , Kuzmin Anton , Pourian Azar Golnaz Taghavi
Published: August 2024

Material science has gone through several evolutionary stages; especially the
discovery of graphene has added one of the most defining chapters in this journey.
Owing to the enormous potential of this material in various applications, a tremendous
pace can be seen in the development of graphene-derived materials and technologies.
The 2D revolution in material science can be marked by the shift from the bulk form of
materials to their intelligent and efficient two-dimensional (2D) analogs and their use
in developing innovative contrivances. Various forms of 2D graphene have recently
evolved, including mainly monolayer graphene, bilayer graphene, graphene oxide,
graphene nanoribbons, and graphene quantum dots. These materials have shown great
potential to revolutionize various aspects of human life, from electronics and actuation
to healthcare and energy.
Its exceptional properties make it an ideal candidate for various applications.
Continuing explorations and epistemological pieces of evidence will likely reveal even
more prospective applications. The book chapter deals with a concise overview of the
structural aspects of graphene, the presence of defects, methods of synthesis, and
functionalization. The chapter will help develop an essential understanding of the
critical aspects of science and recent developments around it. This chapter aims to
provide a quick and easily understandable summary of various complex aspects of it by
reducing irrelevant or extraneous information.
Bone Regeneration and Bone Growth Using Perovskites
Authors: Pavithra A.J. , Anudevi S.D. , Hikku G.S. , Ebenezar K. Kumar
Published: August 2024

Perovskite materials are becoming more popular in biomedical applications,
notably bone tissue engineering and regenerative medicine. Their distinct physical
features, such as high dielectric constant, ambipolar charge transfer, and
ferroelectricity, make them ideal for bone regeneration. Perovskite-based scaffolds may
replicate bone tissue's extracellular matrix and encourage cell behavior, hence aiding
bone tissue regeneration. These materials have the potential to completely transform
bone defect and injury therapy in regenerative medicine. However, issues like
degradation, scalability, toxicity, device interaction, and cost must be solved before
they can be widely used. To overcome these challenges, it is necessary to improve
stability, scalability, and repeatability, reduce toxicity, achieve device compatibility,
reduce manufacturing costs, and develop standardized testing and safety norms. To
completely understand the biocompatibility and long-term effectiveness of perovskite
materials in bone treatment, further studies and development are required. Despite
these difficulties, perovskite materials offer promise in the treatment of bone
abnormalities and fractures by acting as scaffolds for bone regeneration, medication
delivery vehicles, and imaging agents. Overall, perovskite materials have the potential
to improve bone regeneration and advance musculoskeletal disease therapies.
Balancing Between Privacy and Utility for Affect Recognition Using Multitask Learning in Differential Privacy–Added Federated Learning Settings: Quantitative Study
Authors: Benouis Mohamed , Andre Elisabeth , Can Yekta Said
Published: August 2024

Background

The rise of wearable sensors marks a significant development in the era of affective computing. Their popularity is continuously increasing, and they have the potential to improve our understanding of human stress. A fundamental aspect within this domain is the ability to recognize perceived stress through these unobtrusive devices.

Objective

This study aims to enhance the performance of emotion recognition using multitask learning (MTL), a technique extensively explored across various machine learning tasks, including affective computing. By leveraging the shared information among related tasks, we seek to augment the accuracy of emotion recognition while confronting the privacy threats inherent in the physiological data captured by these sensors.

Methods

To address the privacy concerns associated with the sensitive data collected by wearable sensors, we proposed a novel framework that integrates differential privacy and federated learning approaches with MTL. This framework was designed to efficiently identify mental stress while preserving private identity information. Through this approach, we aimed to enhance the performance of emotion recognition tasks while preserving user privacy.

Results

Comprehensive evaluations of our framework were conducted using 2 prominent public datasets. The results demonstrate a significant improvement in emotion recognition accuracy, achieving a rate of 90%. Furthermore, our approach effectively mitigates privacy risks, as evidenced by limiting reidentification accuracies to 47%.

Conclusions

This study presents a promising approach to advancing emotion recognition capabilities while addressing privacy concerns in the context of empathetic sensors. By integrating MTL with differential privacy and federated learning, we have demonstrated the potential to achieve high levels of accuracy in emotion recognition while ensuring the protection of user privacy. This research contributes to the ongoing efforts to use affective computing in a privacy-aware and ethical manner.
Regional Remote Sensing Analysis of Fault Tectonics of the Kola Peninsula and Its Role in Ore Formation
Authors: Minaev Vasilii , Ustinov Stepan , Petrov Vladislav , Svecherevsky Alexey , Nafigin Igor
Published: August 2024

The results of a comprehensive analysis of fault tectonics of the Kola Peninsula, carried out on a regional scale, are considered. Based on a digital relief model, generalized for various scale levels, lineaments were identified manually and automatically. The results obtained in combination with literature data made it possible to carry out tectonophysical reconstructions using the Hancock model. Based on the results of these reconstructions, the proposed areas of tectonic structures were identified that had the greatest hydraulic activity at the time of the introduction of mafic-ultrabasic massifs and dike complexes of pegmatite belts, which are associated with ore deposits of scarce types of strategic minerals of the Kola Peninsula (copper, nickel, chromium, rare metals, etc.) The areas were identified, promising for the discovery of new ore objects.
Akıllı Telefon Sektöründe Elektronik Ağızdan Ağıza İletişimin Tüketicilerin Satın Alma Niyetine Etkisinde Algılanan Kalitenin Aracı Rolü
Authors: Dilek Hasan , Çatı Kahraman
Published: August 2024

Bu araştırmanın amacı akıllı telefon sektöründe elektronik ağızdan ağıza iletişimin satın alma niyetine etkisinde algılanan kalitenin aracı rolünün olup olmadığını tespit etmektir. Araştırmanın örneklemini, 14/01/2023-28/02/2023 tarihleri arasında araştırmaya katılmayı kabul eden 407 kişi oluşturmaktadır. Araştırmanın verileri anket tekniği ile toplanmıştır. Verilerin analizinde SPSS 22.0, SPSS PROCESS macro Model 4 ile bootstrap tekniği kullanılmış ve korelasyon analizi yapılmıştır. Araştırma sonucunda elektronik ağızdan ağıza iletişimin alt boyutu “satın alma ile ilgili bilgi edinme” ile “satın alma niyeti” (r=0.478) ve “topluluk üyeliği ve ekonomik teşvik” ile “satın alma niyeti” (r=0.427) ve “ürünle ilgili bilgi edinme” ile “satın alma niyeti” (r=0.457) arasında pozitif yönlü, orta seviyede ilişki bulunmuştur (p
Lider-Üye Etkileşiminin Örgütsel Bağlılık Üzerindeki Etkisinde İşe Adanmışlığın Aracılık Rolü
Authors: Haskebabçı Fatma Hümeyra , Aykan Ebru
Published: August 2024

Liderler ve çalışanlar arasındaki ikili ilişkiye odaklanan lider-üye etkileşimi teorisi, liderle çalışan arasında yapıcı ve olumlu bir etkileşim kurulmasıyla işletmenin başarısını en üst seviyeye çıkarmayı amaçlamaktadır. İşletmelerde performans artışı ve verimlilik için istenilen bir durum olan işe adanmışlık ve örgütsel bağlılık davranışları da nitelikli bir lider-çalışan etkileşiminden geçmektedir. Lider-çalışan ilişkisinin kalitesi ne kadar yüksek olursa örgütsel bağlılık ve adanmışlık davranışları da ona göre şekillenerek artmaktadır. Bu doğrultuda bu çalışma, liderle çalışanları arasındaki ilişkinin çalışanların işe adanmışlığı ve örgütsel bağlılığı üzerindeki etkisini araştırmaya ve lider-üye etkileşimi ile örgütsel bağlılık ilişkisinde işe adanmışlığın aracı rolüne odaklanmaktadır. Araştırma, Kayseri Organize Sanayi Bölgesinde bulunan işletme çalışanlarına yapılmıştır. 339 çalışandan anket tekniği ile toplanan verilerin sonuçları; lider-üye etkileşiminin çalışanların işe adanmışlık ve bağlılık davranışları ile ilişkili olduğunu ve bu davranışları anlamlı ve pozitif bir şekilde etkilediğini ortaya koymuştur. Ayrıca Process Makro Model-4 ile test edilen işe adanmışlık davranışının, aracı rolü olduğu tespit edilmiştir.
Formulation and Evaluation of Wound Healer Waterproof Spray containing Cymbopogon nardus L. and Musa paradisiaca L. Leaves Wax
Authors: Novitasari Putri Rachma , Dwi Nugroho Agung , Adyaqsa  Prihatmadi Farhan , Kesya Riza Purnama Sarasevita
Published: August 2024

Red lemongrass (Cymbopogon nardus L.) is an Indonesian plant which has potential as a wound healer. Red lemongrass contain essential oil which has the potential effect to treat wounds, such as citral. The citral content in every 1 mL of this essential oil is 32.28%. A wound is an injury-induced disturbance of the tissues' normal anatomical relationships. Wound is basically prone to infection, and it can infect bacteria, such as Staphylococcus aureus bacteria. Water splashes exposed the Staphylococcus aureus bacteria, which then caused an infection. Water is a medium for bacterial growth. In this research, kepok banana leaves wax (Musa paradisiaca L.) is added as a waterproof base to prevent wounds from being splashed by water, because wounds on skin tissue are protected by a layer of wax originating from kepok banana leaves (Musa paradisiaca L.). The aim of this research was to make a waterproof gel spray from red lemongrass essential oil using wax of banana leaves as a waterproof base. The result showed waterproof gel spray preparation has yellowish white colour; a distinctive aromatic odor, pH 6,28; viscosity 135 cps, and dry time 7.5 minutes and it has waterproof properties.
Aerobe Fermentation Enhanced Antioxidant Activity Index of Citrus limon Leaves
Authors: Herlina Santi , Setiawansyah Arif , Hidayati Nurul
Published: August 2024

The chemical composition and antioxidant activity of a natural product are directly correlated with the preparation process which can alter certain enzymatic pathways, leading to the alteration of the production of secondary metabolites affecting its biological activity. This study aims to observe the effects of the pre-extraction process of Citrus limon on its TFC, TPC, and antioxidant activity. Samples were prepared by two different pre-extraction techniques (solar drying and aerobe fermentation) and extracted using ultrasound-assisted extraction with ethanol 96%. The TFC and TPC were measured by a colorimetric method using a spectrophotometer UV-Vis. The antioxidant activity was tested on DPPH and calculated as AAI with ascorbic acid as a standard. The result showed that solar dried sample exhibited higher TFC and TPC than the fermented sample with TFC and TPC values of 32.165 mg QE/g and 335.80 mg GAE/g extract. In contrast, the antioxidant activity assay revealed that fermented samples provided higher antioxidant activity than solar-dried samples and even better than ascorbic acid with an IC50 value of 2.52 µg/mL. The pre-extraction process significantly influences the TFC, TPC and antioxidant activity of Citrus limon.
Effect of Corn Starch and Glycerol Additions on the Characteristics of Capsule Shells from Seaweed Carrageenan
Authors: Ramadita Aisha , Ariyanto Hermawan Dwi
Published: August 2024

Capsule shells are generally made by gelatinee which from animal based. However, the capsule shell has issues related to the permissibility (halalness) and safety. Carrageenan has the potential as an essential ingredient of the capsule shell to replace gelatinee. The focus of this study was to determine the optimal formulation for the preparation of capsule shells. There were 9 different formulations to test the best quality by comparing it with commercial capsule shells. The samples were manually moulded with a dipping pen for 3 s at 45℃. The concentrations of corn starch were 1%, 2%, and 3% w/v and concentration glycerol were 2%, 3%, and 4% w/v. Weight uniformity, specifications, disintegration, and FTIR were analysed to determine the best quality of the capsule shell. The results showed that formula with concentration of 95% of distilled water, 2% w/v of carrageenan, 2% w/v of corn starch and 3% w/v of glycerol fit the standard of capsule shell.
Optimasi Perencanaan Penggantian Pegas Daun pada Truk Hino FM 260 Jd di PT PP Presisi Tbk Proyek Tol Indrapura–Kisaran
Authors: Praditya Ardhi Nur Praditya , Winarto Felixtianus Eko Wismo
Published: August 2024

Pegas daun merupakan komponen penting dari sistem suspensi truk, namun pegas daun dapat mengalami kegagalan prematur akibat kondisi jalan yang ekstrem dan implementasi perawatan yang tidak memadai. Hal ini dapat mengganggu proyek konstruksi dan menyebabkan peningkatan biaya. Sebuah studi dilakukan untuk menyelidiki faktor-faktor yang menyebabkan kegagalan pegas daun pada unit Hino FM 260 JD dalam proyek pembangunan jalan tol Indrapura–Kisaran, Sumatera Utara. Studi ini menemukan bahwa umur rata-rata komponen pegas daun depan lebih pendek daripada umur pakai yang direkomendasikan oleh produsen. Hal ini disebabkan oleh kondisi jalan yang ekstrem di wilayah tersebut, serta implementasi perawatan yang tidak memadai oleh tim proyek. Mengadopsi rekomendasi penggantian baru akan mengakibatkan penurunan efisiensi komponen dan peningkatan harga. Temuan studi ini menekankan pentingnya pemeliharaan dan penggantian pegas daun yang tepat untuk mencegah gangguan dalam proyek konstruksi. Studi ini juga memberikan pandangan mengenai faktor-faktor yang dapat menyebabkan kegagalan pegas daun prematur, yang dapat digunakan untuk meningkatkan keandalan sistem suspensi truk. Hasil analisis memberikan rekomendasi perencanaan penggantian salah satu jenis spring dengan rentang 46.011,62 hingga 51.959,58 kilometer.
Association of Kidney Function with Sodium-Glucose Co-Transporter 2 Inhibitor Discontinuation among US Veterans
Authors: Ikeme Jesse C. , Madden Erin , Lamprea-Montealegre Julio A. , Chu Chi D. , Shlipak Michael G. , McCoy Ian E. , Estrella Michelle M.
Published: August 2024

Key Points

Patients started on sodium-glucose co-transporter-2 inhibitors (SGLT2i) had a 23% risk of discontinuation at 1 year; 41% of these discontinuations occurred within the first 3 months.

Patients with lower kidney function were more likely to experience discontinuation.

Higher rates of SGLT2i discontinuation in patients with CKD may limit the cardiokidney benefits of SGLT2i in real-world practice.

Background

The effect of sodium-glucose co-transporter-2 inhibitors (SGLT2i) on cardiovascular disease and CKD may be limited if discontinued in persons with CKD. We sought to determine whether CKD at SGLT2i initiation was associated with subsequent discontinuation.

Methods

This cohort study used electronic health record data of patients who initiated SGLT2i in the Veterans Health Administration from January 2017 through December 2021. The primary exposure was eGFR category at the time of SGLT2i initiation. The risk of SGLT2i discontinuation, defined by a provider order or expiration of an SGLT2i prescription without resumption in the following 180 days, was estimated using proportional hazards models with inverse probability weights for censoring due to death. Analyses were stratified by year of SGLT2i initiation.

Results

Among the 222,772 patients initiating an SGLT2i during the study period, the median age was 68 (interquartile range, 60–73) years, 95% were male, and median (interquartile range) eGFR was 73 (58–89) ml/min per 1.73 m2. Median follow-up was 1.6 years; 32% experienced SGLT2i discontinuation. Cumulative risk of discontinuation at 1 year was 21%–27% across calendar years; approximately 41% of these discontinuations occurred within the first 3 months. There was a graded association between lower baseline eGFR and greater risk of discontinuation; this association attenuated across calendar years. Those initiating an SGLT2i in 2017 with baseline eGFR of 45–59 and 30–44 had 1.34- (95% confidence interval [CI], 1.21 to 1.49) and 2.04-fold (95% CI, 1.58 to 2.63) risks of discontinuation, respectively, compared with those with eGFR ≥60 ml/min per 1.73 m2. These hazard ratios reduced to 1.05 (95% CI, 1.02 to 1.10) and 1.20 (95% CI, 1.14 to 1.26), respectively, in those initiated in 2021.

Conclusions

A substantial proportion of patients experience SGLT2i discontinuation within a year of initiation. Those with lower eGFR had higher discontinuation rates; however, this trend attenuated over time. Additional studies identifying and addressing factors leading to discontinuation are needed to fully realize the benefits of SGLT2i.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2024_11_26_CJASNNov1911112624.mp3
Prescription for Humanity: Iraqi Medical Education Adds a Dose of Art and Storytelling
Authors: Jani Dr Bushra Juhi
Published: August 2024

In a move bridging the science-humanities gap, Al-Nahrain University Medical College in Iraq integrated storytelling, arts, and ethical reflection into their first-year English course, fostering empathy and cultural sensitivity in future doctors. This experiment, despite challenges like large class size, received overwhelmingly positive student feedback, highlighting the value of engaging content, creative methods, and skill development for well-rounded healthcare professionals. This pioneering effort offers valuable insights and challenges for educators seeking to implement similar medical humanities programs.
Comparison of Proportional Integral Derivative Control and Model Predictive Control for Commercial Vehicles
Authors: Kulkarni Nishad Chandrashekhar
Published: August 2024

Commercial automobiles are significant in transportation, logistics, and delivery solutions. Advanced control strategies have become increasingly crucial with the increasing demand for green and environmentally responsible transportation methods. Proportional Integral Derivative Control and Model Predictive Control have emerged as promising practices for optimizing automobile performance. This paper considerably compares the Proportional Integral Derivative and Model Predictive Controller’s applications, benefits, challenges, and limitations in commercial vehicle technology. Additionally, it offers a compelling case study to illustrate the effectiveness of Model Predictive Control in real-world scenarios concerning Proportional Integral Derivative Control. Furthermore, the paper explores the future scope of Model Predictive Control, aiming to increase understanding and foster research. Ultimately, this study contributes to advancing green and sustainable vehicle generation.
Enhancing Patient Care Through Kubernetes-Powered Healthcare Data Management
Authors: Chinnam Shiva Kumar
Published: August 2024

This comprehensive article explores the transformative impact of Kubernetes on healthcare data processing, highlighting its potential to revolutionize the reliability, scalability, and security of healthcare IT infrastructure. The article delves into the core components of Kubernetes architecture and their relevance to healthcare applications, emphasizing the advantages of containerization in managing complex medical software ecosystems. It examines key reliability features such as automated scaling, self-healing mechanisms, and rolling updates, which are crucial for maintaining the continuous operation of critical healthcare services. The article presents various use cases in healthcare data processing, including the handling of sensitive patient information and ensuring high availability for mission-critical applications. Performance optimization strategies are discussed, showcasing Kubernetes' capability to efficiently manage large data volumes and distributed workloads. The article also addresses the integration of monitoring and logging tools, essential for maintaining system health and regulatory compliance. While highlighting the numerous benefits, the article acknowledges challenges such as data privacy concerns, skills gaps, and legacy system migration. Looking ahead, it explores emerging trends like AI integration, edge computing in healthcare, and hybrid cloud deployments, positioning Kubernetes as a pivotal technology in shaping the future of healthcare IT. This article provides valuable insights for healthcare organizations seeking to enhance their data processing capabilities and IT infrastructure resilience in an increasingly digital healthcare landscape.
Climate Change's Impact on Water Resources in Jammu and Kashmir (India)
Authors: Pandit Dr. Bashir Ahmad
Published: August 2024

Abstract: The effects of climate change on water resources, adaptability, and Water resource-related issues are broadly and intricately intertwined. As a result, the tools used today to deal with these variables and create integrated assessments are complex and fraught with ambiguity. Nonetheless, a lot of researchers have worked hard to create numerical simulation methods that can assess each interaction as well as the combined impact. Problems with floods and droughts are being clarified by numerical simulations using GCM data. They also aid in our comprehension of the effects of human activity and the depletion of freshwater resources in coastal areas as a result of sea level rise. There is some qualitative understanding of the influence on water quality even though no models of water quality under the influence of global warming have been produced yet. Predictions of social and climatic changes have not yet been made, despite the fact that research and talks for the adaptation of water resources have already begun. As a result, it's essential to create numerical models that illustrate how socioeconomic situations and water resources interact.
Comparative Study of Analysis of Pre-Engineering Building using different Code
Authors: Sawant Abaji , Sayagavi Dr. V. G.
Published: August 2024

Abstract: This project focuses on a comparative analysis and design of Pre-Engineered Buildings (PEB) using two different standards: IS 800:2007 (Indian Standard) and AISC (American Institute of Steel Construction), along with a comparison with Conventional Steel Buildings (CSB). Pre-Engineered Buildings have emerged as an efficient alternative to conventional construction due to their cost-effectiveness, faster completion time, and structural adaptability. The study evaluates the performance and design efficiency of PEB under both standards, highlighting the key differences and similarities in their structural design approaches. Through detailed analysis, the project aims to determine the most economical and structurally sound design method, providing insights that can guide future PEB projects in selecting appropriate design standards.
INTERNAL CONTROL ON MILITARY ASSETS ACCORDING TO MILK AL-DAULAH IN ISLAMIC ECONOMIC LAW
Authors: Wilda Nadhiratul Safira  , Zulhamdi
Published: August 2024

This article aims to examine the internal control system of national military assets in Indonesia at the Kuta Alam Banda Aceh barracks, reviewed according to the concept of milk al-daulah. The approach taken by the author is a juridical-empirical study. The research findings indicate that to address issues in the internal control system of assets in the Indonesian National Army (TNI) at the Kuta Alam Banda Aceh barracks, a holistic approach is required to effectively tackle existing challenges. It is crucial to update and refine the inventory process to ensure that asset data is more accurate and current. Implementing an integrated, technology-based asset management system will facilitate tracking and monitoring. Furthermore, asset maintenance should be scheduled regularly and its implementation should be ensured to prevent damage that could increase repair costs. Enhancements in surveillance technology, such as modern CCTV and access control systems, are essential to reduce the risk of theft and damage. Compliance with policies should be strengthened through intensive training and consistent enforcement to ensure procedures are properly followed. Risk management also needs improvement with more effective and proactive mitigation strategies. Additionally, the use of advanced technology can support efficiency in asset management and reporting. Transparency should be increased by providing clear and accessible reporting mechanisms, while budget management should be improved to ensure efficient allocation. Regular personnel training is important to keep their skills relevant, and routine audits and evaluations should be conducted to maintain the effectiveness of the internal control system.
Islamic Spiritual Intelligence and Work Performance: A Literature Review Study
Authors: Agustin Liliza , Izza Wan Nurul
Published: August 2024

This study provides an extensive analysis of the literature regarding the effects of Islamic spiritual intelligence on the productivity of employees. Utilizing a diverse array of academic publications and empirical investigations, the manuscript delves into the conceptual framework of Islamic spiritual intelligence, its constituent elements, and its impact on various aspects of work performance in organizational settings. Moreover, the review delves into intermediary and moderating variables that configure the correlation between Islamic spiritual intelligence and work performance. Furthermore, it discusses practical implications for organizational decision-makers and proposes avenues for future research endeavors.
Gestos metodológicos y distorsiones temporales: estudio de caso con tesistas de diseño durante la pandemia
Authors: Moscoso María Fernanda , Mariona Moncunill-Piñas  , Lúa Coderch
Published: August 2024

El artículo explora el impacto del COVID-19, en su escala temporal, sobre las metodologías que se pusieron en juego en las investigaciones de un grupo de estudiantes de diseño que desarrollaron sus trabajos de grado durante el confinamiento en un centro universitario de Barcelona. Nos preguntamos sobre la variación de la experiencia del tiempo en sus proyectos, de qué manera la experiencia de mundo afectó el curso de las investigaciones y qué podemos aprender de lo ocurrido. A partir de una aproximación etnográfica (entrevistas abiertas), se sostiene, entre otras cosas, que la pandemia generó un fenómeno de desaceleración que hemos relacionado con experiencias temporales que pueden ser leídas como fuga de los regímenes de atención hegemónicos neoliberales. También, que estas distorsiones temporales fueron un acontecimiento queer que condujo al hacer propio, relacionado con la producción de investigaciones centradas en los procesos y el desarrollo de prácticas autorreflexivas.
Secrecy Rate Maximization for Symbiotic Radio Network with Relay-Obstacle
Authors: ONAY Muhammed Yusuf
Published: August 2024

The idea that everything can communicate with each other with high bit rate and low latency is the main goal for next generation communication systems. In this context, allocating spectrum resources and providing energy to each device that can communicate is a big problem. In order to develop different techniques in this regard, symbiotic radio networks (SRNs) have been proposed in the literature. In SRN, devices transmit information to the same receiver by using the communication infrastructure together. However, this situation may create a security problem. In this paper, SRN with relay-obstacle is proposed to test physical layer security (PLS). This model is the first approach that maximizes the secrecy rate of SRN by using the ambient radio frequency resource in the presence of relay-obstacle. There are two different clusters in the system model and each cluster contains a device, a relay and an obstacle. An eavesdropper (ED) overhearing to the signals transmitted by the relays and is blocked by a cooperative jammer. The proposed system model is mathematically modeled and the secrecy rate expression is maximized over the time parameters. In the numerical analysis, the advantages of using the channel symbiotically compared to the nonsymbiotic scenario where the energy harvest-then-transmit (HTT) protocol is used in the literature are evaluated in terms of the reflection coefficient, noise power, signal transmission power and quality of service (QoS) of the devices and its superiority is revealed.
H. pylori-Associated Gastritis, Gastritis after H. pylori Eradication and H. pylori-Negative Gastritis: Algorithm of Diagnosis and Treatment (Literature Review and Resolution of the Expert Panel of the Russian Gastroenterological Association)
Authors: Ivashkin V. T. , Maev I. V. , Lapina T. L. , Kucheryavyy Yu. A. , Abdulkhakov S. R. , Alekseeva O. P. , Alekseenko S. A. , Andreev D. N. , Bakulin I. G. , Bakulina N. V. , Bordin D. S. , Galeeva Z. M. , Dekhnich N. N. , Korochanskaya N. V. , Kuvaev R. O. , Livzan M. A. , Osipenko M. F. , Pirogov S. S. , Simanenkov V. I. , Storonova O. A. , Tertychnyy A. S. , Trukhmanov A. S. , Uspenskiy Yu. P. , Khlynov I. B. , Tsukanov V. V.
Published: August 2024

Aim: to provide the basic points of the Expert Panel of the Russian Gastroenterological Association with discussion of measures to improve diagnostics, treatment and management of chronic gastritis patients.

Key points. In the Russian Federation in 2021 more than 30 million patients diagnosed with “Gastritis and duodenitis” were recorded (K29 in accordance with International Classification of Diseases-10). H. pylori incidence rate in the Russian population has reduced and presently is about 40 %. In chronic gastritis pattern H. pylori-associated gastritis has still dominated though gastritis percent after successful H. pylori eradication, reactive gastropathy (including reflux gastritis) and autoimmune gastritis, has increased. Endoscopic and histologic examinations serve as key diagnostic techniques that provide a means for assessing the ethiology of gastritis, topography and degree of atrophic changes, gastritis staging as per OLGA/OLGIM system that properly correlates with the risk of stomach cancer and determines endoscopic examination strategy. H. pylori eradication therapy of gastritis serves as an etiotropic treatment and makes it possible to prevent progression of atrophy and stomach cancer. Conventional triple therapy combined with bismuth tripotassium dicitrate allows for achieving optimal cure rates of H. pylori eradication. Addition of rebamipide to regimens of H. pylori eradication improves their efficiency. Rebamipide arrests symptoms of dyspepsia in the case of chronic gastritis and functional dyspepsia. The administration of rebamipide for chronic gastritis makes it possible to influence the syndrome of increased epithelial permeability and inflammation, which makes it advisable to study it as a means of preventing stomach cancer and the progression of atrophy in various types of chronic gastritis.

Conclusion. Members of the Expert Panel has approved the algorithm of diagnosis and treatment of H. pylori-associated gastritis, gastritis after H. pylori eradication and H. pylori-negative gastritis at the diagnostic stage in the case of initial presentation and long-term follow-up when needed.
Analisis Gaya Belajar Peserta Didik Kelas VIII Pada Mata Pelajaran IPA Di SMP Negeri 22 Pekanbaru
Authors: Tunnisa Liza Fadillah , Fauziah Nurul
Published: August 2024

Peserta didik memiliki gaya belajar yang berbeda-beda yang dapat mempengaruhi hasil belajar peserta didik. Oleh karena itu, guru sebagai seorang pendidik harus memahami gaya belajar masing-masing peserta didik. Penelitian ini bertujuan untuk mengetahui Gaya Belajar Peserta didik Kelas VIII pada Mata Pelajaran IPA (Biologi) di SMP Negeri 22 Pekanbaru Tahun Ajaran 2022/2023. Penelitian ini menggunakan metode penelitian deskriptif kuantitatif. Populasi dalam penelitian ini adalah 221 Peserta didik yang terdiri dari 6 kelas, dengan jumlah sampel sebanyak 132 peserta didik. Teknik pengambilan sampel menggunakan teknik simple random sampling, dengan ketentuan sampel 20% dari jumlah populasi diketahui jumlah populasi. Teknik pengumpulan data menggunakan angket, wawancara, observasi dan dokumentasi. Hasil penelitian menunjukkan gaya belajar peserta didik dalam pembelajaran IPA (Biologi) di kelas VIII SMP Negeri 22 Pekanbaru yang terdiri dari peserta didik tipe gaya belajar visual dengan persentase 41%, peserta didik tipe gaya belajar auditorial dengan persentase 30% dan peserta didik tipe gaya belajar kinestetik dengan persentase 37%. Berdasarkan hasil dari penelitian maka dapat disimpulkan bahwa gaya belajar peserta didik SMP Negeri 22 Pekanbaru didominasi oleh tipe gaya belajar visual dengan persentase 41%.
Democratização da educação pública: gênero e inclusão na educação
Authors: Silva Auricelia de Aguiar , Silva Welingthon dos Santos , Omizzolo Simone Regina , Almada Francisco de Assis Carvalho de
Published: August 2024

O presente artigo traz uma abordagem sobre a democratização na educação pública a partir das discussões acerca de gênero e inclusão na educação. Em que objetivamos refletir a democratização da escola pública como norteador das discussões de gênero e inclusão educacional. Assim, este trabalho trata-se de uma pesquisa bibliográfica, onde apresentamos elementos históricos que envolvem a trajetória do conceito de gênero, inclusão e o processo de democratização da educação no Brasil. Trazemos também sobre as mudanças sociais, perspectivas e desafios que abarcam a escola pública nos aspectos de uma gestão democrática e inclusão de gênero. A fundamentação teórica utilizada pauta-se em autores como Candau (2020), Hooks (2019), Louro (2002; 2004; 2014), e demais autores do campo da educação que nos permitem compreender a gestão democrática e a inclusão de gênero no meio escolar, refletindo a escola como um espaço de construção da inclusão e diversidade. Com base na discussão sobre gênero e inclusão educacional, percebemos que a democratização da educação pública no viés da inclusão segue uma trilha em que os passos são vagarosos, mas muito tem sido feito, esforços conjuntos para vencer os desafios que se apresentam no desenvolvimento das relações humanas presentes dentro e fora da escola.
O tornar-se professora e a ação pioneira na implantação do ensino superior no interior do sul da Bahia/Brasil na segunda metade do século XX: memória e história de Waldir Pinto Montenegro Matos
Authors: Assis Daisy Laraine Moraes de
Published: August 2024

O interesse pela memória e trajetória de vida da professora Waldir Pinto Montenegro Matos decorreu do processo inicial de investigação sobre a presença da Campanha Nacional de Educandários Gratuitos (CNEG) no sul da Bahia, na primeira metade da década de 1950, objeto do trabalho de pesquisa, cujo foco principal encontrava-se voltado para o movimento de criação dos ginásios “gratuitos” na região cacaueira, durante o período. E, de maneira mais específica, a criação do ginásio da CNEG no município de Ibicaraí. Nesse processo, o nome da professora é destacado. Assim, a partir da memória da formação docente e trajetória profissional de Waldir Pinto Montenegro Matos, busca-se na composição da narrativa histórica, presente neste trabalho, estabelecer uma relação entre a história de vida de Waldir Montenegro e o protagonismo atribuído à docente na implantação do ensino superior no interior da Bahia na segunda metade do século XX, tendo em vista uma maior compreensão sobre como ocorreu esse processo e o papel educacional exercido pela docente na região.
A questão regional brasileira como determinante para a compreensão do processo de metropolização no século XXI
Authors: Marques Leonidas de Santana
Published: August 2024

O Brasil vem apresentando historicamente uma forte questão regional. Pretendemos analisar a relação que se estabelece entre a questão regional brasileira e o processo de metropolização no nosso país no século XXI, dialogando com as dinâmicas de reestruturação produtiva, concentração e desconcentração concentrada. Consideramos tanto o debate teórico sobre o desenvolvimento desigual das relações capitalistas no país quanto dados que denotam o processo de concentração que vem se estabelecendo nas últimas décadas. Partimos de revisão bibliográfica e do levantamento de dados do IBGE. Argumentamos que a metropolização do espaço sob a égide da questão regional brasileira reafirma nossas assimetrias estruturais, agudizando a centralização de capitais na região sudeste e complexificando ainda mais os desafios de superação das desigualdades no Brasil.