bluuebunny/crossref_metadata_2025 huggingface dataset:
MARKETING STUDIES OF CONSUMPTION PREFERENCES AT DEVELOPING DIETARY PRODUCTS
Authors: Biletska Yana , Babenko Vitalina , Gusliev Andrii
Published: October 2019

Results of marketing studies of consumption motivations and preferences at choosing bread for special dietary consumption are presented. It has been established, that 18 % of questioned give advantage to bread with a decreased amount of carbohydrates; 17 % of respondents consume bread without gluten; 13 % give preference to products, including nutrients; 10 % by iodine-containing bread; 7 % and 6 % of questioned give preference to bread with a content of soya and entersorbents. It has been established, that bread with a content of carotene and lecithin is not widely demanded among respondents as 3 % for each one. Studies of % of preferences by flour types in the bread composition allowed to make conclusions that 19 and 17 % of respondents give preference to corn and buckwheat flour due to a higher content of healthy substances, it is also an important advantage that these flour types don’t contain cellulose complexes, present in the composition of wheat and barley flour, preferred by 14 and 11 % of questioned, respectively. It has been established by the experimental way, that 20 % of questioned persons feel a lack of bread with an increased content of protein at the market. 15, 12 and 10 % of respondents want widening the assortment of bread with an increased content of macroelements, vitamins and microelements. 13 and 10 % of questioned feel a lack at the market in such physiological-functional ingredients as polyunsaturated fatty acids and products of gluten-free flour. 8 % of respondents want to see in the retail network products with a content of dietary fiber and antioxidants. 9 % feel a lack of bread with a content of probiotics, 3 % of oligosaccharides. Based on the obtained results, there have been determined consumption advantages: a modern consumer gives preference to products with the improved content, usual organoleptic parameters, long storage term, low price. He/she is guided by the following criteria at buying bread: food value, caloric value, prophylactic properties.
Evaluation of the effective parameters on energy losses of rectangular and circular culverts via kernel-based approaches
Authors: Roushangar Kiyoumars , Matin Ghazaleh Nasssaji , Ghasempour Roghayeh , Saghebian Seyed Mahdi
Published: October 2019

Energy dissipation in culverts is a complex phenomenon due to the nonlinearity and uncertainties of the process. In the current study, the capability of Gaussian process regression (GPR) and support vector machine (SVM) as kernel-based approaches and the gene expression programming (GEP) method was assessed in predicting energy losses in culverts. Two types of bend loss in rectangular culverts and entrance loss in circular culverts with different inlet end treatments were considered. Various input combinations were developed and tested using experimental data. The OAT (one-at-a-time), factorial sensitivity analysis and Monte Carlo uncertainty analysis were used to select the effective parameters in modeling. The results of performance criteria proved the capability of the applied methods (i.e. high correlation coefficient (R) and determination coefficient (DC) and low root mean square error (RSME)). For rectangular culverts, the model with parameters Fr (Froude number) and θ (bend angle), and for circular culverts, the model with parameters Fr and Hw/D (depth ratio), were the superior models. It showed that using the bend downstream Froude number caused an increment in model efficiency. Among the four end inlet treatments, mitered flush to 1.5:1 fill slope inlet yielded more accurate prediction. The sensitivity and uncertainty analysis showed that θ and Hw/D had the most significant impact on modeling, and Fr had the highest uncertainty.
Escólio Geral de Newton - o não-mecanicismo do Principia
Authors: Filho Porfírio Amarilla
Published: October 2019

O Escólio Geral do Livro III dos Princípios Matemáticos da Filosofia da Natureza refere-se a um contexto singular do pensamento de Newton devido aos vários aspectos que o motivaram. Publicado, em 1713, inserido na 2a edição do Principia, o Escólio Geral trouxe aspectos em seu interior que não foram considerados tão relevantes para a 1a edição. O mesmo tom que assume o prefácio de Roger Cotes, cujo escopo esta centrado em aspectos mais metafísico em relação aos prefácios da edição anterior, nota-se no Escólio Geral. Este ensaio procura demonstrar que o Escólio Geral promove um debate metafísico diante da filosofia da natureza em relação ao contexto da modernidade, cujo objetivo é promover uma visão não apenas mecânica da natureza, mas também não-mecânica, que se distancia, de certo modo, da 1a edição, fornecendo, neste sentido, um suporte para a investigação dos elementos metafísicos da filosofia newtoniana.
Philosophical and epistemological foundations of a post-structural writing lesson
Authors: Meisels Marlene V
Published: October 2019

In the world of research or instruction, operating from different philosophical and epistemological traditions results in very different kinds of classrooms. I use a post-structural perspective to show how a teacher could conduct a college developmental writing lesson. Included is an overview of post-structural theory. I suggest one way to accommodate diversity in the classroom is by building both teachers’ and students’ awareness of epistemological positions, because some positions empower students more than others. Another reason for examining epistemologies is to cultivate awareness of the social, religious, political, and other assumptions or agendas with which we enter the classroom.
O Platão de Deleuze
Authors: Gomes Rafael Alvarenga
Published: October 2019

Este artigo pretende investigar o interesse de Gilles Deleuze pela filosofia de Platão. Para tanto, optamos por apresentar, ainda que brevemente, as demarcações sobre as quais Deleuze ergue seu trabalho filosófico. Sendo assim, ideias como as de Espaço, Imagem do Pensamento e Pensamento sem Imagem serão mostradas como alicerces desse empreendimento filosófico. Então, tendo em vista a apresentação de como funciona o procedimento deleuziano, mostraremos o que há no pensamento platônico que interessa a Deleuze, a ponto de chegarmos a afirmar que existe um Platão de Deleuze.
Qualitative and Quantitative Analysis of Resveratrol and Oxyresveratrol by Liquid Chromatography
Authors: Khambadkar Rajeshree , Ravindran Selvan , Chahar Digamber Singh , Utekar Srushti , Tambe Amlesh
Published: October 2019

Introduction:

Resveratrol and its monooxygenated metabolite oxyresveratrol
were the subject matter of intense research due to their medicinal value. Absorption, distribution,
metabolism and excretion are important to understand the bioavailability and pharmacokinetic
profile of resveratrol and oxyresveratrol. Quantification of resveratrol and
oxyresveratrol is essential for both in vitro and in vivo studies.

Methods:

During in vitro drug metabolism studies, both qualitative and quantitative information
are essential to understand the metabolic profile of resveratrol and oxyresveratrol. In
the present study, a simple and stable method is outlined using high performance liquid
chromatography to quantify both resveratrol and oxyresveratrol. This method is suitable to
understand the metabolic stability, plasma stability, pharmacokinetics and toxicokinetics of
resveratrol and oxyresveratrol.

Results:

Generally, in vitro incubation studies are performed at high concentrations and in
vivo studies are carried out at both high and low concentrations, therefore high performance
liquid chromatography method is demonstrated as a suitable technique to quantify resveratrol
and oxyresveratrol.

Conclusion:

Retention time of resveratrol and oxyresveratrol from liquid chromatography
qualitatively confirm its identity.
The usage of geographic information systems for operational epidemiological analysis of influenza incidence in the territory of Rostov-on-Don including mass events
Authors: Slis’ S. S. , Kovalev E. V. , Nenadskaya S. A. , Vodop’yanov A. S. , Lyalina L. V.
Published: October 2019

Objective: the assessment of spatial distribution of influenza in the metropolis and creation of the geographic information system (hereinafter – GIS) « Influenza: Rostov-on-Don «, containing data on places of case registration.

Materials and methods: statistical data on influenza cases based on primary and final reports, PCR studies were used. Geocoding of addresses was performed using the servers Nominatum and the Satellite. For development of GIS we used free software QGIS version 3.2.2. As the cartographic basis OpenStreetMap community maps were used.

Results: construction of variograms («heat maps») revealed the formation of several risk areas («epidemiological spots»), the boundaries of which do not coincide with the boundaries of the administrative districts of the city.

Conclusions: the analysis showed that distribution of each of the subtypes of influenza A virus in the territory of Rostov-on-Don in the 2018-2019 season has specific features. We showed that in conditions of the megalopolis the spatial analysis which was carried out without taking into account the administrative boundaries provided more accurate results in comparison with traditional zoning.
The First “Jerusalem” Consul K.M. Basili and the Protection of Russian Pilgrims in Jerusalem
Authors: Вах Кирилл , Vah Kirill
Published: October 2019

The paper explores the perception of the Russian pilgrimage to the sacred sites of the Orthodox East by the Russian government represented by the central office of the Ministry of Foreign Affairs and by the local diplomats. Having analyzed the archival sources, the author concludes about different assessments and approaches to the phenomenon of pilgrimage across different levels of the Russian government. This helps to take a new perspective and look at the causes of the alienation and mistrust between the Russian authorities and representatives of the Greek Orthodox Church hierarchy in Jerusalem, as well as explain the lack of an adequate response in St. Petersburg to the exacerbating problems with the Russian pilgrims in the East. In addition, the paper researches K.M. Basili’s role and specific contribution to the developing issue of the Russian pilgrims in the Holy Land.
P.A. Vyazemsky’s Poetic Heritage
Authors: Жаткин Дмитрий , Zhatkin Dmitriy , Васильев Николай , Vasil'ev Nikolay
Published: October 2019

The paper focuses on the preliminary systemic insights into P.A. Vyazemsky’s poetic heritage (1792–1878) based on the analysis of his numerous lifetime and posthumous publications (proved author’s, co-author’s, anonymous), the collection of letters written by Vyazemsky and his contemporaries, archival materials from the collections of the Russian State Archive of Literature and Art, Manuscript Research Department of the Russian State Library, Manuscript Department of the Institute of Russian Literature, Manuscript Department of the National Library of Russia, Manuscript Department of St. Petersburg State Theatre Library. They are based on the alphabetical bibliography of Vyazemsky's poems compiled by the project team, including almost 1,400 works (indicating their printed or archival sources with the necessary textual comments). The previously unknown poems that were not published or printed anonymously for some reason are revealed and partly put into scientific circulation. Among them, there are the patriotic poems “To the Current War”, “Who Needs Whom More?” attributed erroneously to other authors and popular in the 19th century. This research helped to broaden the understanding of Vyazemsky’s activity as a poet.
Russian-German Scientific Colloquium “Soviet-German Economic Relations in 1917–1991” (Voronezh, July 11–12, 2019)
Authors: Коршунов Юрий , Korshunov Yuriy
Published: October 2019

The paper describes the international scientific event on economic history. Its studies, which are based mainly on new archival documents, are of practical importance, because they nurture not only scientific knowledge and promote networking, but can also help to improve interstate economic relations and strengthen the positive image of Russia abroad.
TRANSPORT POLICY ABROAD: TRAINING CENTERS AND MAIN RESEARCH AREAS
Authors: Fedyakin Aleksey V , Fedyakin Ivan V
Published: October 2019

The article based on the analysis of public sources examines the structure, goals and main directions of works of foreign scientific and educational centers in the field of transport policy - an independent area of the state activity that has (due to the infrastructural nature of the object of its regulation which is transport) characteristics of universality and reveal the close relationship and overlapping with many other areas (economic, social, innovation, industrial, regional, etc.). Transport policy as a field of research has links and intersections with the goals of a number of other political science areas and sub-disciplines (primarily with public policy and management, political regionalism, international relations and geopolitics, etc.). The authors state that theoretical and applied research in this complex and interdisciplinary field are carried out by organizations that are structural units of educational institutions and by independent institutions. The main trend of their research on general and special issues of transport policy is interdisciplinary approach used during the analysis. As for training, it is carried out by a number of foreign universities - both classical and specialized (mainly technical) universities. At the same time, it is primarily interdisciplinary in nature, based on a combination of areas such as politics, public administration, strategic management, transport economics, etc., which is reflected in the curriculum and in the content of individual disciplines. However, such training has not yet become a widespread phenomenon, and the diverse possibilities of political science in many courses remain underused. The article makes a general conclusion that theoretical and applied research, as well as training in the field of transport policy retain significant reserves, which are still very far from being exhausted. This is especially true of political science, whose heuristic and educational potential for the needs of the transport industry remains undiscovered.
relações entre espaço urbano e cultura
Authors: Coelho Cláudio Novaes Pinto
Published: October 2019

A Internacional Situacionista foi um movimento político-cultural que, durante as décadas de 1950 e 1960, colocou o espaço urbano como foco de um projeto de transformação social. Os acontecimentos de maio de 1968 foram o ponto culminante dessa tentativa de combinação entre revolução política e revolução cultural. O propósito desse artigo é contribuir para uma reflexão a respeito da herança das propostas e práticas da Internacional Situacionista. A base para essa reflexão será a diferenciação estabelecida por Debord entre a cidade-história e a cidade-espetáculo. Será levado em consideração, ainda, o contexto contemporâneo, onde os espaços urbanos são fundamentais para o processo mundial de acúmulo de capital, e quando a produção cultural está cada mais vez mais integrada a esse processo. A existência de produções culturais questionadoras do status quo será pensada tendo em vista esse contexto
Espaço urbano e as suas transformações pela lente da semiótica urbana
Authors: Torres Desire Menezes , De Almeida Adriano Rodrigues
Published: October 2019

Entendendo a cidade como produtora de sentido por meio de suas imagens, se faz necessário compreender como estes signos influenciam a paisagem urbana. Esta pesquisa tem como objetivo geral analisar o potencial de influência da imagem do varejo nas transformações da espacialidade urbana, tendo como especificidades, verificar os lugares de fixos e de fluxos; verificar a história ambiental e sua relação com o usuário; identificar as transformações físico-contextuais da imagem do varejo. A metodologia utilizada caracteriza este estudo como uma pesquisa descritiva, qualitativa, documental e bibliográfica e emprega a técnica de observação do espaço urbano em questão e as demais interações com o mesmo, por meio de análises semióticas urbanas da cidade de Londrina-PR, na década de 1940 e no ano de 2018. Pode-se afirmar que a cidade enquanto produtora de sentido por meio de suas imagens constrói sua paisagem utilizando como suporte a comunicação da sua espacialidade.
La investigación social proceso de seguimiento continuo
Authors: Torres-Flórez Dagoberto
Published: October 2019

Hablando de investigación como algo reflexivo, sistemático, controlado y crítico, hace que quien se involucra en estas tareas lo haga en forma planeada y organizada, por ello definido el problema, se investiga y se lleva a una respuesta que permita solucionar el problema, sin embargo, todo esto lo podemos desarrollar con las palabras pregunta a ejemplo: el qué (tema o cuestión), para que (objetivo), por qué (problema), dónde (área), cuándo (cronograma), quienes (equipo de trabajo), con qué (financiación).

Al iniciar, es la formulación del problema la que nos va a marcar la ruta, que permitirá planear la investigación para que nos lleve a un resultado óptimo, por ello es importante formularlo en un enunciado que responda de manera clara, precisa y concreta el qué y para qué. En esta planeación delimitar el tema y campo de investigación ayuda a que se comprenda el alcance tanto en posibles resultados, como magnitud del tiempo necesario para su ejecución.
Estudio de las profesiones desde el enfoque de la disciplina en la administración de empresas en el proyecto Tuning en América Latina
Authors: Juarez Fonseca Veronica , Pérez Paredes Alfredo
Published: October 2019

El estudio de las profesiones ha pasado por varios momentos históricos, desde conceptuales hasta academicistas y con enfoques diversos, desde un análisis social crítico, al capitalista y actualmente a un estado de conocimiento que escasamente ha sido trabajado en México, pero que ha servido de base para  la vía del currículo en la Educación Superior como un puente entre la profesión y el egresado a partir de las características que emanan de ésta; así desde el  desde el enfoque en el área económico administrativa es que versa esta investigación. Aludiendo a la profesión Agüero Aguirre, (2003) establece características de un contexto que determina el entorno nacional e internacional de las demandas del administrador, para conducirlo a la vía del currículo.
Multifunctional public open spaces for sustainable cities: Concept and application
Authors: Zivkovic Jelena , Lalovic Ksenija , Milojevic Milica , Nikezic Ana
Published: October 2019

The idea that multifunctional open spaces support sustainable urban
development has been widely accepted in theory and intensively used in
practice of urban planning and design. It is based on the assumption that
multifunctional spaces bring a wider spectrum of environmental, social and
economic benefits to urban areas. And yet, multifunctionality of space is
still a vague and diffuse concept that needs further clarifications. Besides
that, different academic disciplines understand and use this concept in
different ways. This makes the application of the concept difficult to
assess and manage in relation to different aspects of urban sustainability.
Through the literature review, this paper analyses and compares how the
concept of multifunctionality is used in various spatial disciplines (urban
planning and design, landscape architecture) in order to better understand
and relate its different dimensions, applications and expected benefits for
sustainable development. Based on this, a new, relational and
multidimensional conceptualisation of the multifunctionality of public open
spaces is proposed for analysis and assessment of urban design solutions. It
is further applied and discussed in relation to students projects from
?Ecological urban design studio? from the University of Belgrade Faculty of
Architecture, as visions for development of multifunctional public open
spaces in modernist mass housing area of ?Sava Blocks? in New Belgrade,
Serbia.
Production of Mg-Li alloys by aluminothermic vacuum reduction
Authors: Wang Y.-W. , You J. , Wang A.-G. , Peng J.-P. , Di Y.-Z.
Published: October 2019

Mg?Li alloys are the lightest metallic construction materials and one of the most representative light alloys. The process of producing Mg?Li alloys by vacuum aluminothermic reduction, using magnesite and lithium carbonate as raw materials, was studied. The influence of reduction parameters on the extents of reduction of MgO and Li2O was investigated. The results show that Mg?Li alloys can be produced by vacuum aluminothermic reduction using calcined magnesite and lithium carbonate. MgO was relatively easier to reduce by aluminum than Li2O. Almost all MgO was reduced to Mg and more than 96% of Li2O was reduced to Li. The main phase in the reduction slag was Li2O?5Al2O3. The reaction mechanism was discussed. Vacuum aluminothermic reduction can be considered as a highly efficient and environmental friendly method for producing Mg?Li alloys.
Problematización del acoso escolar en estudiantes: una alternativa de intervención
Authors: Jocobi Zúñiga María de Guadalupe , Cruz Pérez Oscar , Ocaña Zúñiga Jesús , García Lara Germán Alejandro
Published: October 2019

En este artículo se presentan los resultados de una investigación que se enfocó en una estrategia de intervención para discutir el tema del acoso y la violencia en el contexto escolar. Se trata de una investigación cualitativa que incluyó grupos de discusión, así como la observación participante de 33 estudiantes de una secundaria pública de la localidad de Ciudad Obregón, Sonora, en el municipio de Cajeme. El análisis se enfocó en la manera de convivir de los jóvenes y la problematización del acoso escolar por parte de los adolescentes. Los resultados sugieren que los alumnos son capaces de identificar el acoso escolar como un problema que está presente en la convivencia con sus pares, basado en agresiones tanto físicas como verbales que evidencian un abuso de poder, intencionalidad y repetición entre los involucrados. Sus percepciones sobre la problemática demuestran que existe una convivencia hostil entre los agresores, irrespeto entre los compañeros y problemas de comunicación.
A regional Alpine graphite décollement level beneath the NW Pannonian Basin
Authors: Tari Gábor Csaba , Németh Viktória , Horváth † Ferenc , Wesztergom Viktor
Published: October 2019

The so-called Transdanubian Conductivity Anomaly (TCA) of the Hungarian part of the NW Pannonian Basin has been well known for more than five decades. The exceptionally low resistivity (i.e. 1–2 Ωm) zone has a very large areal extent (on the order a few thousand km2) and it is an entirely subsurface anomaly occurring at depth between circa 3–15 km, with no corresponding outcrops. Various geological explanations of this enigmatic crustal-scale geophysical anomaly range from invoking sub-horizontal Alpine nappe contacts to sub-vertical dikes with graphite and/or saline fluid content. Only one possible analogue outcrop area was considered for the high conductivity anomaly so far, namely the Drauzug/Gailtal area of the Eastern Alps in Austria, some 300 km to the West from the TCA area. Previous attempts to find correspondence between the TCA and prominent seismic reflectors seen on 2D seismic reflection profiles were based on data acquired by research institutions. This study systematically correlates, for the first time, the TCA with 2D industry seismic reflection data in the same area. Our new results show a very strong correlation between the subsurface extent and location of the TCA with various sub-horizontally oriented Cretaceous Alpine nappe surfaces. In addition, we draw on the latest structural correlation of the Alpine nappe stack of the Transdanubian Range with its proper tectonic counterpart in the Eastern Alps.At the southern edge of the Upper Austroalpine units in northern Styria, in the Veitsch Nappe of the Greywacke Zone, numerous graphite localities are known historically. These laterally extensive graphite units in NW Styria formed as the result of greenschist-grade metamorphism of a Carboniferous coal sequence during the Cretaceous. For the first time, we describe here one well penetration of possibly age-equivalent graphitic units in NW Hungary. Correlation of the magnetotelluric anomaly with the distinct reflection seismic signature suggests that the same Palaeozoic graphitebearing Upper Austroalpine units should be present at 3–15 km depth in our study area.Therefore we propose that the best explanation for the observed extent and geometry of the TCA is the presence of graphite in subhorizontal, tectonically thinned detachment surfaces at the base of the Upper Austroalpine nappe edifice of NW Hungary
Glucogenosis Hepática. Características clínicas, laboratoriales e imagenológicas en pacientes pediátricos menores de 15 años
Authors: Ochoa Miguel , Miranda Kevin , Guilcapi Christian , Giler Natasha , Arguello María , Aldean Jorge
Published: October 2019

Antecedentes: La glucogenosis (GSD) hepática es una enfermedad hereditaria autosómica recesiva caracterizada por la alteración del depósito de glucógeno en los tejidos. La enfermedad se presenta con hepatomegalia, debilidad muscular y retraso del crecimiento. Esta patología usualmente se diagnostica clínicamente a partir de los 6 meses de edad cuando la ingesta de alimentos del lactante es más espaciada y puede debutar con sintomatología de hipoglicemia. Debido a la inespecificidad de la presentación clínica de la enfermedad es muy importante la sospecha diagnóstica desde los centros de primer nivel de atención y su derivación oportuna a centros de especialidad. Objetivo: Evaluar y describir el perfil nutricional y clínico en pacientes menores de 15 años con Glucogenosis Hepática. Método: Se describe una serie de casos de 14 pacientes menores de 15 años con diagnóstico clínico de GSD hepática, atendidos en la consulta de Gastroenterología y Nutrición Pediátrica del Hospital Carlos Andrade Marín entre 2016 y 2018. El diagnóstico se lo realizó de acuerdo a la clínica que presentó cada paciente como la presencia de distensión abdominal, hepatomegalia, adinamia, retraso en el crecimiento y datos laboratoriales como niveles de glicemia en sangre periférica, transaminasas, y realización de elastografía entre los principales. Se analizaron datos sociodemográficos, antropométricos, de laboratorio (transaminasas, glicemia periférica) y elastografía hepática. Para el análisis de datos se creó una base de datos en Microsoft Excel 2013 y se procesó con el programa Epi Info 7. Resultados: En este grupo de casos, los tipos específicos de GSD hepática fueron tipo IX, 57,14% (8), tipo III, 28,57% (4) y tipo Ia-b, 14,29% (2) pacientes. La prevalencia de características clínicas ante la sospecha de la GSD hepática fueron: hepatomegalia 100% (14), y retraso en el crecimiento el 64,3% (9). De acuerdo a los exámenes de sangre periférica los valores promedio de transaminasas hepáticas (AST/TGO U/L) (ALT/TGP U/L) y glucosa, fueron de 364±384, 302±255 y 61±15 mg/dL, respectivamente. La elastografía con la que se evaluó el nivel de fibrosis hepática al momento del diagnóstico arrojó los siguientes resultados: F0 (no fibrosis hepática) en el 28,57% (4), F1 con el 28,57% (4), F2-F3 con el 35,71% (5), y F4 7,14%. Conclusión: La Glucogenosis es una patología que debería ser sospechada a tiempo en centros del primer nivel de salud para luego referir oportunamente los casos a los centros de referencia. La hepatomegalia y el retardo en el crecimiento son signos cardinales de alerta para la sospecha de esta patología.
Carta de la Federación Médica Ecuatoriana
Authors: Carrasco Santiago
Published: October 2019

Quito, 7 de octubre de 2019 

La Federación Médica Ecuatoriana desde su institucionalización presentó el interés gremial de mantener un medio de difusión del quehacer científico de los médicos del país.

Es por este motivo, que vio la luz la revista científica EUGENIO ESPEJO, con el apoyo de todos los colegios médicos provinciales, y el aporte de varios colegas, que tuvieron la oportunidad de ver su producción científica médica impresa en un documento del más alto nivel técnico.

Los Editores, los hoy responsables de la continuidad de este registro del arte y ciencia de nuestra profesión, han hecho un esfuerzo extraordinario para la estructuración e indexación, dándole el rigor que la ciencia exige, en estos momentos de la historia de la medicina nacional, y de la comunidad internacional, relacionada con los avances y actualización de la información que el médico requiere para su practica diaria, en beneficio de una atención de calidad para nuestros pacientes.

Esperamos entonces que esta revista aporte a la comunidad médica difundiendo nuestra experticia en este arte y ciencia, que tanto en el Ecuador como en Latinoamérica los colegas producen; y que el conjunto de galenos a los que este documento llegará sea de su interés y ayuda para la toma de decisiones basados en una evidencia científica del más alto nivel.

Dr. Santiago Carrasco D.

VICEPRESIDENTE DE LA FME.
PENGARUH MODEL LATIHAN FARTLEK TERHADAP DAYA TAHAN AEROBIK ATLET SEKOLAH SEPAKBOLA PSTS TABING
Authors: Atradinal Atradinal
Published: October 2019

Masalah penelitian adalah rendahnya kemampuan daya tahan aerobic pemain sepakbola PSTS Tabing. Penelitian bertujuan untuk menemukan jawaban yang akurat secara ilmiah tentang ada atau tidaknya hubungan pengaruh model latihan fartlet terhadap daya tahan aerobic atlet sekolah sepakbola PSTS Tabing. Penelitian ini merupakan eksperimen semu (quasi exsperimental). Populasi dalam penelitian ini adalah pemain sekolah sepakbola PSTS Tabing berjumlah 112 orang. Pengambilan sampel dilakukan dengan teknik purposive sampling, yakninya pemain U-16 sampai U-18berjumlah 18 orang. Pengumpulan data dilakukan dengan cara melakukan tes awal daya tahan aerboik dengan yo-yo test. Analisa data dan pengujian hipotesis menggunakan teknik analisis komparasi dengan menggunakan rumus uji beda mean (uji t) dengan taraf signifikan α = 0,05. Dari analisis data yang dilakukan diperoleh hasil : Terdapat pengaruh yang signifikan dari model latihan fartlek terhadap daya tahan aerobik atlet sekolah sepakbola PSTS Tabing, dengan perolehan koefisien uji “t” yaitu thitung = 7,329 >ttabel = 2,110.
Literatura infantil e temas difíceis: mediação e recepção
Authors: Barros Lúcia Maria , Azevedo Fernando
Published: October 2019

Os temas difíceis, ou fraturantes, têm presença cada vez mais assídua na literatura para a infância publicada em Portugal. Essas temáticas integram as tendências contemporâneas, sobretudo, pela forma como são tratadas, pelos gêneros editorais a que vão dando corpo (entre os quais se destaca o álbum) e pela vontade (e necessidade) de que delas se aproxime o seu destinatário preferencial. As realidades sociais em que vivemos hoje tornam esses temas emergentes, requerendo que eles sejam tratados com a seriedade e a dignidade necessárias à sua compreensão e à consequente compreensão da realidade. Analisa-se um pequeno corpus literário de potencial recepção leitora infantil, sobre guerra, morte e bullying. Servindo o propósito do questionamento e da reflexão sobre assuntos dos quais o adulto tende a afastar a criança, são apresentadas sugestões de abordagem às obras em contexto familiar. O envolvimento de pais e crianças de 7-8 anos na exploração dos textos, a diversidade de abordagens e os produtos daí resultantes são reveladores do potencial que a atual literatura para a infância encerra, não apenas na missão de formar leitores de livros, mas, sobretudo, leitores do mundo e cidadãos felizes.
A literatura infantojuvenil na contemporaneidade: desafios, controvérsias e possibilidades
Authors: Kirchof Edgar Roberto , De Souza Renata Junqueira
Published: October 2019

A literatura infantojuvenil vem passando por transformações, muitas delas relacionadas com o surgimento de novas tecnologias para produção e distribuição de textos e com as novas configurações sociais e culturais que emergem no cenário contemporâneo. Assim, as obras mais recentes trazem inovações tanto no que diz respeito à forma – e mesmo aos formatos – quanto aos temas abordados. Diante desse contexto, são discutidas duas principais questões: as razões pelas quais alguns temas são considerados difíceis ou polêmicos para crianças e jovens em livros infantojuvenis e os novos formatos dessa literatura. Com base na semiótica da cultura, o artigo sustenta que a ideia de que um tema é difícil, polêmico ou inadequado para ser abordado em livros destinados a crianças e jovens está diretamente relacionada com assimetrias existentes entre as concepções de infância e juventude de autores e certos grupos de leitores. No caso dos novos formatos, apresenta-se um panorama relativo às principais transformações desencadeadas pelas tecnologias digitais no universo infantojuvenil.
The evaluation of competitive position of EU-28 economies with using global multi-criteria indices
Authors: Kiseľáková Dana , Šofranková Beáta , Onuferová Erika , Čabinová Veronika
Published: October 2019

Research background: Under the current conditions of increasing competitiveness and interdependence, national economies are more influenced by the global business environment and its development. Constantly changing economic, social, political aspects, and many other factors, cause the differences in the global competitiveness of economies, so the economies are forced to analyze their competitive level more complexly. Despite that, there is a lack of research studies analyzing the international competitiveness of EU-28 economies from the point of view various multi-criteria indices.
Purpose of the article: The paper investigates the relations between the Global Competitiveness Index (GCI) and other selected multi-criteria indices, namely the Global Innovation Index (GII), the Doing Business Index (DBI), the Economic Freedom Index (EFI) and the Corruption Perceptions Index (CPI) in the case of EU?28 economies.
Methods: In order to investigate the relations between the global competitiveness and selected multi-criteria indices affecting the EU?28 economies, the multiple linear regression analyses were applied. The multiple regression model was quantified for every single year, as well as, the regression model using the average score of all analyzed indices. The secondary data concerning the scores of individual indices were collected based on annually published online reports over the period of 2014?2018.
Findings & Value added: The research confirmed that there is a statistically significant dependence between the global competitiveness, corruption and the level of innovation potential within the EU?28 economies. Besides, we identified the worst results in the context of competitiveness evaluation especially in the area of corruption and innovation activities. In this regard, the issue of insufficient innovation development and inappropriate corruption perception is considered to be key determinants influencing the assessment of the global competitiveness of the EU?28 member states. In our opinion, to improve the competitiveness of these countries, targeted activities should be implemented in the frame of national competitive strategies, programs, and policies.
HUBUNGAN POLA ASUH IBU BEKERJA DENGAN PERKEMBANGAN SOSIAL ANAK USIA PRASEKOLAH
Authors: Irawan Rifki , Verawati Metti , Putri Dianita Rifqia
Published: October 2019

Setiap anak adalah individu yang unik, karena faktor bawaan dan lingkungan yang berbeda. Maka pertumbuhan dan perkembangan anak juga berbeda. Perkembangan sosial anak dapat dipengaruhi oleh pola asuh orang tua yaitu ibu. Dalam mengasuh anak ibu cenderung menggunakan pola asuh tertentu. Penggunaan pola asuh ini memberikan dampak perkembangan terhadap bentuk-bentuk perilaku tertentu pada anak. Banyak anak usia prasekolah menunjukkan perilaku sosial yang kurang kondusif dan pelayanan bimbingan perkembangan perilaku sosial anak yang belum sistematik dan terarah. Tujuan penelitian ini untuk mengetahui hubungan pola asuh ibu bekerja dengan perkembangan sosial anak usia prasekolah di TK Muslimat NU 001 Ponorogo.Penelitian kuantitatif, dengan menggunakan jenis rancangan korelasi yang mengkaji dan mengetahui hubungan antara variabel dengan menggunakan pendekatan cross sectional, dengan jumlah r0esponden 67 orang. Hubungan pola asuh ibu bekerja dengan perkembangan sosial anak usia prasekolah di TK Muslimat NU 001 Ponorogo dianalisis dengan menggunakan Fisher’s Exact.Hasil penelitian menunjukkan bahwa ada hubungan yang signifikan antara pola asuh ibu bekerja dengan perkembangan sosial anak usia prasekolah  dengan p value = 0,000 dan contingency coefficient = 0,562.Penelitian ini dapat disimpulkan bahwa pola asuh ibu bekerja menentukan perkembangan sosial anak usia prasekolah. Disarankan kepada ibu bekerja untuk menerapkan pola asuh demokratis sebagai salah satu upaya untuk mendukung proses perkembangan anak yang optimal.
SS-Coprime Modules
Authors: Hadi Inaam Mohaamed ali
Published: October 2019

Let R be a commutative ring with unity and M is a unitary left R-module . In this paper , we introduce the notion of strongly S-coprime modules, where M is called strongly S-coprime briefly (SS-Coprime) if for each r R , r2M is small in M implies rM=0 . We investigate many properties about this concept. Moreover many relations between it and other related concepts, are given. Â Â Â
A new species of Linaria sect. Supinae from Sierra de Gredos (Sistema Central mountains, Iberian Peninsula)
Authors: Luceño Modesto , Fernández-Mazuecos Mario , Vargas Pablo
Published: October 2019

AbstractUna especie nueva de Linaria sect. Supinae en la Sierra de Gredos (Sistema Central, Península Ibérica)Linaria vettonica Luceño, Mazuecos & P. Vargas, a new species of Linaria sect. Supinae, is described. It is a narrow endemic inhabiting the southern hills of the western and central massifs of Sierra de Gredos (Sistema Central mountains, Iberian Peninsula). The five populations found occur on siliceous, sandy soils of Quercus pyrenaica woodland clearings and slopes. L. vettonica can be distinguished from Linaria caesia by the densely glandular-pubescent inflorescence, dark purple corolla and brown seeds with tuberculate disc, and from L. aeruginea by its erect fertile stems and dark purple -never blackishcorolla.Key words: Linaria, Sierra de Gredos, narrow endemic, taxonomy, seed micromorphology. ResumenSe describe Linaria vettonica Luceño, Mazuecos & P. Vargas, una nueva especie de Linaria sect. Supinae. Se trata de un endemismo restringido que se distribuye por las vertientes meridionales de los macizos occidental y central de la Sierra de Gredos (Sistema Central, Península Ibérica). Las cinco poblaciones encontradas aparecieron sobre suelos arenosos silíceos en claros y laderas de bosques de Quercus pyrenaica. L. vettonica se distingue de L. caesia por sus inflorescencias densamente glandular-pubescentes, corolas de color púrpura oscuro y semillas marrones con disco ornamentado con numerosos tubérculos. De L. aeruginea se distingue por sus tallos fértiles erectos y sus flores de color púrpura oscuro, nunca negruzcas.Palabras clave: Linaria, sierra de Gredos, endemismo restringido, taxonomía, micromorfología de semillas.
Genetics and inflammatory profile in tobacco dependence
Authors: Eugenia Budin Corina , Rajnoveanu Ruxandra , Bordea Ioana Roxana , Marginean Corina , Domokos Bianca , Dantes Elena , Adina Todea Doina
Published: October 2019

The state of health of the population is determined by a set of factors belonging to human biology, environment, behaviors, and the health system (preventive, curative, and rehabilitative). Any of these factors can alter both individual and community health.

The primary reason for tobacco dependence is nicotine addiction. Dopamine is released from the neurons located in the mesolimbic system. Nicotine stimulates the release of dopamine from these receptors. The genetic determination of nicotine dependence is determined by the subtypes of nicotine acetylcholine receptors (nAChRs) and conditioned by chromosome mutations at chromosomes 15q25.1, 8p11.21 or 20q13.12-q13.32.

Low-amplitude systemic inflammation is demonstrated in all smokers and is confirmed by elevated levels of C-reactive protein, fibrinogen, Interleukin-6, and increased leukocyte levels. Moreover, coagulation and endothelial function markers such as hematocrit, plasma or blood viscosity, D-dimers, circulating adhesion molecules, tissue plasminogen activator, have also modified values in smokers.
Critical state constitutive models and shear loading of overconsolidated clays with deviatoric hardening
Authors: Rachdi Sara , Jahangir Emad , Tijani Michel , Serratrice Jean-François
Published: October 2019

This paper presents an enhanced constitutive model integrating deviatoric hardening with a modified yield surface for overconsolidated clayey soils in a general framework of Cam-clay type models. Its performance was assessed with the simulation of drained and undrained triaxial tests on three clays at different consolidation states in comparison to two critical state models. The proposed model satisfactorily estimates the shear resistance, while capturing the smooth nonlinearity of the soil response.

Shear triaxial tests at constant mean pressure were performed on an overconsolidated marl to study the shear response. Their simulation attests the importance of deviatoric hardening integration.
Makna Simbolik Komunikasi Antarbudaya pada Perayaan Grebeg Sudiro di Kota Solo
Authors: Gama Betty , Kusumawati Henny Sri
Published: October 2019

Grebeg Sudiro merupakan salah satu perayaan budaya di Indonesia yang menunjukkan keharmonisan antara suku Jawa dan masyarakat Tionghoa yang bertempat tinggal di wilayah Solo khususnya di Kampung Sudiroprajan. Penelitian ini bertujuan untuk mengetahui makna simbolik perayaan Grebeg dan Sudiro  pada Tahun Baru Imlek di Solo, proses terbentuknya Grebeg Sudiro sebagai salah satu bentuk komunikasi antarbudaya antara penduduk pribumi dengan etnis Tionghoa, dan implikasi Grebeg Sudiro terhadap perkembangan kebudayaan Tionghoa serta perkembangan pariwisata di kota Solo. Metode penelitian yang digunakan adalah kualitatif dengan pendekatan fenomenologis. Teknik pengumpulan data dilakukan dengan wawancara, observasi dan analisis dokumen. Validitas data menggunakan trianggulasi data dan metode. Hasil penelitian menunjukkan Grebeg Sudiro merupakan rangkaian acara kegiatan di Kampung Sudiroprajan untuk menyelaraskan keberagaman dalam menciptakan harmonisasi antara warga Jawa dan Tionghoa. Kolaburasi perayaan Grebeg Sudiro dan Tahun Baru Imlek merupakan pertunjukan yang layak ditonton. Lampu-lampu lampion di kawasan Pasar Gede bagi masyarakat Solo dianggap hanya sebagai hiburan untuk dinikmati
Patrón de citoquinas en niños con dengue hemorrágico en Neiva, Colombia
Authors: Salgado Doris M. , Garzón Marisol , Vega Rocío , Panqueba Cesar , Narváez Carlos F. , Rodríguez Jairo Antonio
Published: October 2019

Las citoquinas juegan un papel crítico en la patogénesis de la fiebre dengue hemorrágico (FDH) y han sido usadas como marcadores de severidad. En este estudio se midieron los niveles de cinco citoquinas en niños infectados con dengue y se correlacionaron con el choque y las formas complicadas tales como miocarditis, hepatitis o sangrado. Método: 30 pacientes que cumplían los criterios de la OMS para FDH fueron incluidos y clasificados en dos grupos: grupo 1, sin choque (grado I y II) y grupo 2, con choque (grado III y IV). Niveles séricos de TNFá, IL-6, IL-10. IL-4 e IFN ã fueron medidos por ELISA en el primer día de la defervescencia y comparados con los respectivos niveles de 28 niños sanos. Resultados: de los 30 pacientes, 9 fueron clasificados en el grupo número 1 (media de edad de 67 meses) y 21 en el grupo 2 (media de la edad 42 meses). Diferencias estadísticamente significativas fueron encontradas entre niños infectados con dengue y controles sanos: sanos IL-6 (5,2 pg/ml), grupo 1 (485 pg/ml) (p = 0,002) y grupo 2 (190 pg/ml) (p = 0,001); TNFá, grupo control (70 pg/ml), grupo 1 (586,7 pg/ml) (p = 0,021) y grupo 2 (320,7 pg/ml) (p < 0,001) y para IFNã, grupo control (12,3 pg/ml), grupo 2 (27,5 pg/ml) (p = 0,019). Sin embargo, no se encontró correlación entre las citoquinas y el choque o las otras formas evaluadas. IL-4 e IL-10 no fueron diferentes en ninguno de los grupos analizados. Conclusión: IL-6, TNFá e IFNã están elevadas en niños con FDH, pero no hubo correlación con las formas severas de choque.
Paciente con infarto agudo de miocardio secundario a enfermedad coronaria por ectasia y flujos lentos
Authors: Durán Luis Fernando , Bedoya Trujillo Nataly
Published: October 2019

El flujo coronario lento fue inicialmente descrito en 1972; consiste en un desorden microvascular coronario caracterizado por el paso retardado de contraste en ausencia de enfermedad coronaria obstructiva epicárdica(1). A continuación se presenta el caso clínico de un paciente de 49 años al que se le realiza un diagnóstico de infarto agudo de miocardio, quien posteriormente en el cateterismo cardiaco evidenció ectasia coronaria y enfermedad coronaria por flujos lentos, recibiendo anticoagulación oral en rango terapéutico; nueve días después del alta reingresa con cuadro clínico de síncope cardiogénico con dolor torácico típico, se confirma por criterio electrocardiográfico, además de aumento de troponina, un nuevo infarto agudo de miocardio.
Organizing Pneumonia Induced by Ablative Radioembolization for the Treatment of Hepatic Metastatic Renal Cell Carcinoma
Authors: Devcic Zlatko , Rojas Carlos A. , Elboraey Mohamed , Toskich Beau
Published: October 2019

Organizing pneumonia is a recognized complication after external beam radiotherapy of breast and lung cancer but has not been described after radioembolization. A 67-year-old female who underwent ablative trans-arterial radioembolization for the treatment of hepatic metastatic renal cell carcinoma adjacent to the diaphragm presented with computed tomography findings of asymptomatic organizing pneumonia in the lower lobes. A follow-up computed tomography 8 months after conservative management demonstrated near-total resolution of the previous pulmonary parenchymal disease. The patient continues to remain asymptomatic and shows no evidence of residual tumor 10 months after radioembolization.
Mammographic Breast Density Assessed with Fully Automated Method and its Risk for Breast Cancer
Authors: Saikiran Pendem , Ramzan Ruqiya , S. Nandish , Kamineni Phani Deepika , Priyanka  , John Arathy Mary
Published: October 2019

Objectives:

We evaluated the association between breast cancer and breast density (BD) measured using fully automated software. We also evaluated the performance of cancer risk models such as only clinical risk factors, density related measures, and both clinical risk factors and density-related measures for determining cancer risk.

Materials and Methods:

This is a retrospective case–control study. The data were collected from August 2015 to December 2018. Two hundred fifty women with breast cancer and 400 control subjects were included in this study. We evaluated the BD qualitatively using breast imaging-reporting and data system density and quantitatively using 3D slicer. We also collected clinical factors such as age, familial history of breast cancer, menopausal status, number of births, body mass index, and hormonal replacement therapy use. We calculated the odds ratio (OR) for BD to determine the risk of breast cancer. We performed receiver operating characteristic (ROC) curve to assess the performance of cancer risk models.

Results:

The OR for the percentage BD for second, third, and fourth quartiles was 1.632 (95% confidence intervals [CI]: 1.102–2.416), 2.756 (95% CI: 1.704–4.458), and 3.163 (95% CI: 1.356–5.61). The area under ROC curve for clinical risk factors only, mammographic density measures, combined mammographic, and clinical risk factors was 0.578 (95% CI: 0.45, 0.64), 0.684 (95% CI: 0.58, 0.75), and 0.724 (95% CI: 0.64, 0.80), respectively.

Conclusion:

Mammographic BD was found to be positively associated with breast cancer. The density related measures combined clinical risk factors, and density model had good discriminatory power in identifying the cancer risk.