bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of Expressed miRNAs in Human Rheumatoid Arthritis Using Computational Approach – Discovery of a New miR-7167 from Human
Authors: Raj Christian Simon Durai , Thirugnanasambantham Krishnaraj , Islam Mohamed Ibrahim Hairul , Sudalaimuthu Mathan Kumar , Sundaram Sandhya , Ashok Ganapathy , Senthilkumar Venugopal , Muralidaran Senguttuvan , Subramanian Saravanan
Published: December 2018

Background:

Rheumatoid Arthritis (RA) is a chronic inflammatory and autoimmune disease
leading to bones and joints destruction. It is one of the major causes of lifetime disability and
mortality among humans in the developing and developed countries. It was evident that epigenetic
dysregulation is related to the pathogenesis of RA. MicroRNAs (miRNAs) are small non-coding
RNAs that are epigenetic regulators for diverse biological processes and also provided novel molecular
insights in the formation of arthritis.

Objective:

The influences of miRNAs in the alteration of gene regulation during the pathogenesis of
arthritis were exposed in recent years.

Method:

The computational approach to identify miRNA through EST-based homology is more
powerful, economical and time-efficient. In this study, we applied EST-based homology search to
identify miRNAs responsible for the development of arthritis in human beings.

Results:

Our study on 36519 ESTs in human RA condition revealed the expression of four miRNAs,
HSA-miR-198, HSA-miR-4647, has-miR-7167-5p and has-miR-7167-3p. The present study is the
first report about has-miR-7167 that was homologous to Macaca mulatta.

Conclusion:

The predicted targets of these identified miRNAs revealed many biological functions in
the pathogenesis of RA. Further elaborated studies on these miRNAs will help to understand their
function in the development of RA and the use of miRNAs as therapeutic targets in the future.
Ajuste y selección de modelos matemáticos para predecir el volumen total fustal de Tectona grandis en Nuevo Urecho, Michoacán, México
Authors: Telles Antonio Ricardo , Gómez Cárdenas Martín , Alanís Rodríguez Eduardo , Aguirre Calderón Oscar Alberto , Jiménez Pérez Javier
Published: December 2018

El objetivo fue ajustar y seleccionar un modelo matemático para predecir volumen total del fuste para una El objetivo fue ajustar y seleccionar un modelo matemático para predecir el volumen fustal de Tectona grandis L. f. en una plantación de 11 años de edad en Nuevo Urecho, Michoacán. La muestra analizada fue de 128 árboles, a los que se les midió el diámetro de tocón, diámetro normal y el diámetro a distintas secciones, desde la altura de tocón hasta altura total. Se ajustaron seis modelos de volumen fustal mediante el procedimiento Model del paquete estadístico SAS 9.2®. La selección del modelo se hizo a partir de la suma de cuadrados del error (SCE), la raíz del error medio cuadrático (REMC) y R2adj además de la significancia de sus parámetros. Se verificó el cumplimiento de los supuestos de normalidad, homogeneidad de varianzas e independencia de la frecuencia de residuos. Se generó un criterio de calificación que jerarquizó cada estadístico en función al orden de importancia, siendo mejores aquellos con el valor más bajo en la calificación total. El modelo de Meyer fue el de mejor ajuste con SCE= 0.0399, REMC= 0.0179 y R2adj= 0.8246. La prueba de Shapiro-Wilk (0.97), White´s Test (13.00) y la de Durbin-Watson (2.0112) no violan los supuestos de la regresión y garantizan la eficacia del modelo para la estimación de la variable dependiente. Este modelo se considera apropiado para predecir con mayor precisión el volumen fustal en función del diámetro normal (d) y la altura total (AT) de T. grandis en plantaciones con condiciones físicas y biológicas similares a las del sitio de este estudio.
Pengaruh model pembelajaran inkuiri terhadap keterampilan berpikir kritis dan hasil belajar peserta didik dalam pembelajaran PPKn
Authors: Sulianti Ani , Murdinono Mukhamad
Published: December 2018

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran inkuiri terhadap: (1) keterampilan berpikir kritis dan (2) hasil belajar peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang. Penelitian ini merupakan penelitian quasi experiment. Instrumen yang digunakan adalah observasi dan tes. Data dianalisis dengan menggunakan uji-t. Hasil penelitian, adalah sebagai berikut: (1) Terdapat pengaruh yang signifikan model pembelajaran inkuiri terhadap keterampilan berpikir kritis peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang pada Kompetensi Dasar menganalisis indikator ancaman terhadap negara dalam membangun integrasi nasional dengan Bhineka Tunggal Ika. (2) Terdapat pengaruh yang signifikan model pembelajaran inkuiri terhadap hasil belajar peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang pada Kompetensi Dasar menganalisis indikator ancaman terhadap negara dalam membangun integrasi nasional dengan Bhineka Tunggal Ika.Kata kunci: inkuiri, keterampilan berpikir kritis, hasil belajar. THE INFLUENCE OF INQUIRY LEARNING MODEL ON CRITICAL THINKING SKILLS AND STUDENT LEARNING OUTCOMES IN PPKn LEARNINGAbstractThis research aims to determine the effect of inquiry model on: (1) critical thinking skills and (2) learning outcomes in learning civic education of thr students of SMA Negeri 3 Lumajang. This research is a quasi experiment. The data were collected through observation and test.the data were analyzed by using the t-test. The result of this research are as follows. (1) There is a significant effect of inquiry model in critical thinking skill in learning civic education of the students of SMA Negeri 3 Lumajang on the basic competence “analyze indicators of threats to the country in building national integration with unity in diversity”. (2) There is a significant effect of inquiry model on the learning outcomes in learning civic education of the students of SMA Negeri 3 Lumajang on basic the competence “analyze indicators of threats to the country in building national integration with unity in diversity”.Keywords: inquiry, critical thinking skills, outcomes
Pengaruh media pembelajaran terhadap hasil belajar ekonomi ditinjau dari gaya belajar siswa SMA Negeri
Authors: Nurwidayanti Dewi , Mukminan Mukminan
Published: December 2018

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar ekonomi pada siswa yang menggunakan media pembelajaran power point dengan media konvensional pada kelompok siswa dengan gaya belajar visual dan gaya belajar auditorial. Penelitian ini merupakan penelitian eksperimen dengan desain faktorial 2 x 2, menggunakan tes awal (pretest) dan tes akhir (posttest). Penelitian dilakukan di SMAN 4 Yogyakarta dan SMAN 9 Yogyakarta. Populasi penelitian adalah seluruh siswa kelas X SMA Negeri 4 dan SMA Negeri 9 Yogyakarta. Sampel penelitian sebanyak 83 siswa yang diambil dengan teknik simple random sampling. Teknik analisis data menggunakan analisis deskriptif dan uji beda anova dua jalur. Hasil penelitian menunjukkan: Terdapat perbedaan hasil belajar siswa yang pembelajarannya menggunakan media power point dan media konvensional dimana rerata hasil belajar dengan media power point lebih tinggi dibanding menggunakan media konvensional baik itu pada kelompok gaya belajar visual dan kelompok gaya belajar auditorial. Terdapat interaksi antara media pembelajaran dan gaya belajar dalam mempengaruhi hasil belajar Ekonomi.Kata kunci: media pembelajaran, gaya belajar, hasil belajar ekonomi THE EFFECT OF INSTRUCTIONAL MEDIA TOWARD ECONOMIC LEARNING OUTCOMES JUDGING FROM LEARNING STYLES OF SENIOR HIGH SCHOOLAbstractThis study aims to determine differences in economic learning outcomes in students using learning media power point with conventional media in visual style student groups and students auditory style. This research is an experimental research with 2 x 2 factorial design, using pretest and final test (posttest). The research was conducted at SMAN 4 Yogyakarta and SMAN 9 Yogyakarta. The population is all students of class X SMAN 4 Yogyakarta and SMAN 9 Yogyakarta. The sample of research is 83 students taken with simple random sampling technique. The technique of data analysis using descriptive analysis and difference test of two-way ANOVA. The results showed: There are differences in learning outcomes of students who learn by using power point media and using conventional media where the average of learning outcomes with power point media was higher than using conventional media in the visual learning style group and the learning style group. There is a significant interaction between learning media and learning style in influencing the learning result of Economics.Keywords: instructional media, learning style, learning outcomes
Development of microprocessor learning media using zilog z-80 for vocational school students of electronic engineering expert program
Authors: Fathia Nurul Fitri , Hanafi Ivan , Rif’an Muhammad
Published: December 2018

This development research aims to develop microprocessor learning media using Zilog Z80. The Learning Media quality is based on the following aspects: (1) media feasibility according to subject matter experts and media experts; (2) effective based on students ability test by pre test and post-test. The developed cycles and procedures refer to the ADDIE model (analysis, design, development, implementation, and evaluation). This development research produces learning media as microprocessor kits training and e-Learning namely “µProsessor” as learning support. Data analysis techniques to test the effectiveness of learning media using Paired Samples T-Test and Using a Likert scale to test the feasibility of learning media. The research results show that the feasibility of learning media is enough with a high score of above 88% and Paired Samples Test results for media effectiveness show an increase in the value of significant microprocessor capabilities. Measuring the improvement of the ability of students' microprocessors using N-gain (normalized gain). The results of the calculation of N-gain in the large group is 0.72 in the high category. Interpretation of the results of the research can be concluded that effective learning media as a learning media for microprocessors.
Conservation Challenges of Heritage Building Reuse in Nigeria: A review of decision-making models
Authors: Umar Salim Bashir , Said Ismail
Published: December 2018

African countries including Nigeria are enriched with heritage properties embraced with legacy and architectural values depicting a sense of identity. They deserve to be conserved for future generations. However, the properties are continuously ignored and destroyed due to redundancy and injudicious decision. Hence, this paper aimed at reviewing decision-making models adopted mostly in developed countries for possible suitability in developing countries. Meta-analysis was conducted where eight decision-making models were deduced. The practical implications and limitations of the models were acknowledged. The findings were appropriately reviewed and harmonized to suit and enhance optimum quality of conserving heritage assets in developing countries.
Development of a Mobile Phone App to Promote Safe Sex Practice Among Youth in Stockholm, Sweden: Qualitative Study (Preprint)
Authors: Nielsen Anna , Bågenholm Aspasia , De Costa Ayesha
Published: December 2018

BACKGROUND

Mobile health (mHealth) has been shown to be effective in increasing knowledge of sexual health among youth. To date, evaluations mostly refer to interventions delivered via computer, email, and text messages. The possibility of downloading apps on mobile devices has opened up opportunities to develop engaging interventions on safe sexual health promotion. To attract young users and have them engage with a sexual health app, it is important to involve youth in intervention development.

OBJECTIVE

This study aimed to obtain input from youth on the content of a mobile phone app intended to promote safe sex and increase condom use among youth in Stockholm.

METHODS

This study was conducted at the Youth Health Clinics (YHC) in Stockholm County, Sweden. A total of 15 individual in-depth interviews and 2 focus group discussions (with youth aged 18-23 years) were conducted at the YHC in Stockholm. Areas explored were: (1) youth perceptions of condom use (advantages and obstacles), (2) perceptions of mHealth to promote safe sexual practices, and (3) content development for a mobile phone app to promote safe sex.

RESULTS

The smartphone app was developed based on the categories that emerged from the data. With regard to content, youth requested sex education, including information on sexually transmitted infections. In addition, condom-specific information, including practical usage technique, advice on how to have the condom talk, and how to decrease shame related to condom use, was requested. Youth suggested different modes to deliver the content, including text messages, movie clips, and push notifications. It was suggested that the tone of the messages delivered should be fun, entertaining, and supportive. The inputs from youth influenced the development of the following sections of the app: Condom Obstacles and Solutions; Quiz; Games; Self-Refection; Challenges; Stories by Peers (stories from peers and information from a doctor); Condom Tips, Pep Talk, and Boosting; and Random Facts.

CONCLUSIONS

It is important to use input from youth when developing a smartphone intervention since the success of the intervention largely depends on the level of engagement and usage by youth. Furthermore, if proven efficient in increasing condom use, it is important that the development, including content and mode, is thoroughly described so that the intervention can be replicated. Likewise, if proven inefficient, it is important to learn from mistakes to improve and adjust the intervention. The effect of this smartphone app on safe sexual practices among youth is being evaluated in a pragmatic randomized controlled trial in Stockholm (ISRCTN13212899) and will be reported separately.
Mobile Health Adoption in Mental Health: User Experience of a Mobile Health App for Patients With an Eating Disorder (Preprint)
Authors: Anastasiadou Dimitra , Folkvord Frans , Serrano-Troncoso Eduardo , Lupiañez-Villanueva Francisco
Published: December 2018

BACKGROUND

Despite the worldwide growth in mobile health (mHealth) tools and the possible benefits for both patients and health care providers, the overall adoption levels of mHealth tools by health professionals remain relatively low.

OBJECTIVE

This study aimed (1) to investigate attitudes of health care providers and mHealth experts toward mHealth tools in the health context in general, and this study aimed (2) to test the acceptability and feasibility of a specific mHealth tool for patients with an eating disorder (ED), called TCApp, among patients and ED specialists.

METHODS

To this purpose, we conducted an explorative qualitative study with 4 in-depth group discussions with several groups of stakeholders: our first focus group was conducted with 11 experts on mHealth from the Catalan Association of Health Entities; the second focus group included 10 health care professionals from the Spanish College of Doctors of Barcelona; the third focus group involved 9 patients with an ED who had used the TCApp over a 12-week period, and the fourth and last focus group involved 8 ED specialists who had monitored such ED patients on the Web.

RESULTS

The focus groups showed that health care providers and mHealth experts reported barriers for mHealth adoption more often than facilitators, indicating that mHealth techniques are difficult to obtain and use. Most barriers were attributed to external factors relating to the human or organizational environment (ie, lack of time because of workload, lack of direct interest on a legislative or political level) rather than being attributed to internal factors relating to individual obstacles. The results of the mHealth intervention study indicate that the TCApp was considered as easy to use and useful, although patients and the ED specialists monitoring them on the Web reported different adoption problems, such as the inability to personalize the app, a lack of motivational and interactive components, or difficulties in adhering to the study protocol.

CONCLUSIONS

In general, this paper indicates that both health professionals and patients foresee difficulties that need to be addressed before comprehensive adoption and usage of mHealth techniques can be effectively implemented. Such findings are in line with previous studies, suggesting that although they acknowledge their possible benefits and cost-effectiveness, health care providers are quite resistant and conservative about integrating mHealth technologies in their daily practice.
Correlation of Limb Bioimpedance to Echocardiographic Indicators of Congestion in Patients with NYHA Class II/III Heart Failure (Preprint)
Authors: Accardi Andrew , Heywood Thomas , Daleiden-Burns Anne
Published: December 2018

BACKGROUND

The treatment of heart failure (HF) in the United States is estimated to exceed $30 billion each year and is anticipated to increase to a staggering $70 billion by the year 2030. This makes the management of HF one of the leading challenges Medicare will face in the years to come. Traditional methods to detect impending congestion such as body weight and physical examination findings are often non-specific and lack sensitivity making them inadequate to recognize fluid overload and prevent decompensation. It has been suggested that bioimpedance spectroscopy (BIS) can be used as a surrogate marker for detecting fluid overload and therefore, serve as an adjunct to clinical exam findings.

OBJECTIVE

This study examines the relationship between a BIS device and echocardiographic parameters associated with volume overload with same day measurements in the first 8 patients with NYHA Class II/III HF on an IRB approved protocol.

METHODS

Each patient was followed 3 times a week for 4 weeks within the hospital outpatient setting. At each visit BIS measures were recorded for whole body as well as arms and legs. Additionally, signs and symptoms, weight and echocardiograph findings were all recorded.

RESULTS

Correlations of BIS measurements with echo parameters were performed. The leg impedance measurement correlated strongly with echo findings; inferior vena cava (IVC) size (p=0.001), right atrial pressure (RAP) (p<0.001), and pulmonary artery systolic pressure (PAS) measurements (p<0.001).

CONCLUSIONS

Preliminary findings demonstrated excellent correlations with BIS measurements and IVC size, right atrial pressure and pulmonary artery systolic pressure measurements which suggest a possible alternative method to detect fluid overload despite the small sample size. Trending a patient's impedance using the SOZO device at home or the practitioner's office may assist clinicians in providing more accurate, individualized HF care. 

CLINICALTRIAL

. IRB approval was obtained for this study (Scripps IRB #IRB-16-6852).
Public Opinions on Using Social Media Content to Identify Users With Depression and Target Mental Health Care Advertising: Mixed Methods Survey (Preprint)
Authors: Ford Elizabeth , Curlewis Keegan , Wongkoblap Akkapon , Curcin Vasa
Published: December 2018

BACKGROUND

Depression is a common disorder that still remains underdiagnosed and undertreated in the UK National Health Service. Charities and voluntary organizations offer mental health services, but they are still struggling to promote these services to the individuals who need them. By analyzing social media (SM) content using machine learning techniques, it may be possible to identify which SM users are currently experiencing low mood, thus enabling the targeted advertising of mental health services to the individuals who would benefit from them.

OBJECTIVE

This study aimed to understand SM users’ opinions of analysis of SM content for depression and targeted advertising on SM for mental health services.

METHODS

A Web-based, mixed methods, cross-sectional survey was administered to SM users aged 16 years or older within the United Kingdom. It asked participants about their demographics, their usage of SM, and their history of depression and presented structured and open-ended questions on views of SM content being analyzed for depression and views on receiving targeted advertising for mental health services.

RESULTS

A total of 183 participants completed the survey, and 114 (62.3%) of them had previously experienced depression. Participants indicated that they posted less during low moods, and they believed that their SM content would not reflect their depression. They could see the possible benefits of identifying depression from SM content but did not believe that the risks to privacy outweighed these benefits. A majority of the participants would not provide consent for such analysis to be conducted on their data and considered it to be intrusive and exposing.

CONCLUSIONS

In a climate of distrust of SM platforms’ usage of personal data, participants in this survey did not perceive that the benefits of targeting advertisements for mental health services to individuals analyzed as having depression would outweigh the risks to privacy. Future work in this area should proceed with caution and should engage stakeholders at all stages to maximize the transparency and trustworthiness of such research endeavors.
Swab2Know by Euro HIV EDAT: An HIV-testing approach using oral fluid samples and online communication of test results in Europe. (Preprint)
Authors: Platteau Tom , Agusti Benito Cristina , Florence Eric , Fransen Katrien , Fernàndez-Lopez Laura , Ooms Lieselot , Vermoesen Tine , Simões Daniel , Vukelič Blaž , Lixandru Mihai , Slaaen Kaye Per , Casabona i Barbarà Jordi ,   Euro HIV EDAT Study Group
Published: December 2018

BACKGROUND

HIV remains a public health concern in Europe. Increased testing among key populations is considered an integral part of combination HIV-prevention. Epidemiological patterns differ throughout Europe, reflecting different key populations. In order to diagnose people unaware of their infection, swab2know offered free testing for HIV in various settings.

OBJECTIVE

In this project, we aim to assess the feasibility and effectiveness of an HIV-testing approach using oral fluid samples and Web-based delivery of test results for different key populations throughout Europe.

METHODS

Online and outreach self-sampling was offered between September 2015 and September 2017. Samples were processed in a laboratory, and validated test results were communicated through a secured website. In case of a reactive test result, the participant needed to confirm this result using state-of-the-art confirmation procedures on a blood sample. Close follow-up of participants who did not pick up their results, and those with reactive results, was integrated in the project’s methodology.

RESULTS

During 24 months, 3613 samples were collected among 3037 participants. Most samples (N = 2253; 62.4%) were collected during outreach activities, and 1360 (37.6%) via online ordering of sampling kits. The majority of samples was collected among MSM (N=2789; 77.2%), followed by migrants (N=292; 8.1%) and sex workers (N=532; 14.7%). Testing history (ever tested before), number of sexual partners and successful delivery of test results varied strongly between countries and key populations. Overall, the vast majority of participants received their test result (3025/3613; 83.7%). Participants who ordered a sampling kit online were more likely to receive their test result compared to people participating during outreach actions (96.1% vs. 76.3%). Of 3613 samples, 3485 (96.5%) tested negative, 61 (1.7%) weak reactive, 55 (1.5%) reactive, and 12 (0.3%) invalid. In total, 35 participants were newly diagnosed with HIV, representing 1.2% (35/3037) of all participants. Twenty-six of them (74.3%) were successfully linked to care.

CONCLUSIONS

We demonstrated a successful implementation of an HIV testing approach collecting oral fluid samples during outreach and online activities, and remote online result communication. The yield of the project was high in terms of the number of participants, and in reaching the right people. Improving linkage to care, and reducing the number of false reactive test results should be emphasized. This HIV testing approach should be used primarily among key populations, and collected information should be shared with public health administrations for reliable monitoring and evaluation.
Analisis kepuasan pemustaka terhadap kualitas layanan perpustakaan di perguruan tinggi vokasi dengan metode servqual dan importance-performace analysis
Authors: Rachmadita Renanda Nia , Arninputranto Wibowo
Published: December 2018

Introduction. Library in Vocational Higher Education is required to provide the best services in facilities, learning environmentbased on the characteristics of vocational education. This study aims to measure the level of satisfaction of library services  in vocational colleges. Data Collection Method. The questionnaires were distributed to 150 respondents including students and lecturersbased on five dimensions of Servqual. Data Analysis. The analysis was conducted  by identifying  the gap between perception and expectation using Importance-Performance Analysis method. Results and Discussions. Overall, the analysis if the gap for all Servqual dimensions was negative. Some services needto be  improved  to meet user expectations. By using Importance-Performance Analysis, itwas found that the attribute P10 (Library needs to provide an adequate online catalog) should be prioritized..Conclusions. It is expected that the library can improve the services based on the users’ needs.
Makna profesi pustakawan: studi fenomenologi tentang profesi pustakawan lulusan diklat calon pustakawan tingkat ahli (CPTA)
Authors: Oktaviani Niar Eka , Yanto Andri , Rachmawati Tine Silvana
Published: December 2018

Introduction. Librarians build their librarianship concept based on self understanding of interpretation of the reality from their professional activities in the workplace. This research is very important as the study of a concept of librarian profession from CPTA is limited in Indonesia. Data Collection Method. The research method used is qualitative with phenomenology approach. Five librarians participated in the IPDN Library. Results and Discussions. The results show the three meanings of librarian were as a valuable profession, as a promising profession and as an information service provider. The self-concept found in this study has been seen from three aspects: psychological aspects include a sense of confusion, a sense of comfort, a sense of pride and professional. Further, the social aspects involve being underestimated, harmonious relationships, respecting each other, creating intense competition and having good relationship. Physical aspects include  being clean and neat, smart, versatile, attractive as a modern librarian. The motivation to become a librarian is salary and other incomes, competition, and opportunity to improve. Conclusions. The paper shows that librarians interpret themselves as a profession that has a value from the material perspective because it has benefits and allowances related to their work performance. Further research is needed to study a comparison between librarians formal education and librarians from CPTA related to their motivation.
Game-Based Learning: Academic Games sebagai Metode Penunjang Pembelajaran Kewirausahaan
Authors: Hidayat Rahmat
Published: December 2018

Entrepreneurship plays an important role for the national economic growth. Therefore, the chararacter development, the way of thinking, and entrepreneurial skills within community are things that should be sought. Consequently, the effective entrepreneurship learning methods are needed, specifically kind of method that based on adult learning approach. This article seeks to bring the study of digital games technology as an entrepreneurial learning media. Hence, the description of the characteristics of games and learning aspects that can be facilitated by digital games technology will be mainly discussed. In addition, this article describes the learning process through digital media, instructional techniques that can be integrated in digital media, and assessment feedback method in academic games learning. Some examples of digital games used for learning in entrepreneur­ship courses are presented to provide a concrete picture. In brief, this article supports the use of digital games technology in entrepreneurial learning.
PEMBANGUNAN APLIKASI PEMASARAN PERUMAHAN DEVELOPER KOTA PADANG DENGAN KONSEP COSTUMER RELATIONSHIP MANAGEMEN (CRM)
Authors: Mahessya Raja Ayu , Kurnia Hezy
Published: December 2018

Abstract

The House is one of the primary requirements for the community. But sometimes to get information on home ideals must take that much because of the need to visit the offices of developer the related needs and income. Problems of information and time is less effective make the researcher wants to help people who want to get information about housing so there is no need to leave the Office only requires internet access so that everyone who wants to buy a home can get the information detail, because on the web developer developer gathering designed in the field in one of the web so that people who want to have a home can look, choose, which corresponds to a location location, price, specs and a home equipped with galleries. This is because the activities of the Customer Relationship Management (CRM) is still traditional. The absence of an organized marketing well, many industrial developers who do marketing and consumer saving data offline. In this research will be an application of Customer Relationship Management to marketing. Consumer relationship should be done with a web media with a variety of on-site CRM. So consumers will be comfortable in the update information.

Abstrak

Rumah merupakan salah satu yang sudah menjadi kebutuhan primer untuk masyarakat. Tetapi terkadang untuk mendapatkan informasi tentang rumah idaman harus memakan waktu yang banyak karena harus mengunjungi kantor-kantor developer yang terkait yang sesuai dengan kebutuhan dan pendapatan. Permasalahan informasi yang kurang dan waktu yang kurang efektif membuat peneliti ingin membantu masyarakat yang ingin mendapatkan informasi tentang perumahan sehingga tidak perlu meninggalkan kantor hanya membutuhkan akses internet sehingga setiap orang yang ingin membeli rumah bisa mendapatkan informasi yang detail, karena pada web yang dirancang mengumpulkan developer developer dikota padang dalam satu web sehingga masyarakat yang ingin mempunyai rumah bisa melihat, memilih, yang sesuai dengan lokasi yang strategis, harga, spesifikasi rumah dan dilengkapi dengan galeri. Hal ini disebabkan karena kegiatan Customer Relationship Management (CRM) yang masih traditional. Tidak adanya pemasaran yang terorganisasi secara baik, Banyak Pelaku industri developer yang melakukan pemasaran dan menyimpan data konsumen secara konvensional. Dalam Penelitian ini akan dibangun suatu aplikasi Customer Relationship Manajemen untuk pemasaran. Hubungan dengan konsumen akan dilakukan dengan suatu media web dengan berbagai fasilitas CRM. Sehingga konsumen akan nyaman dalam update informasi.
SISTEM PENDUKUNG KEPUTUSAN ANALISIS KEPUASAN MAHASISWA TERHADAP PENGGUNAAN SARANA LABORATORIUM SISTEM INFORMASI
Authors: Darwas Rahmadini
Published: December 2018

Abstract
Laboratory is one of the supporting facilities in im[roving the learning process. Problems found by students regarding the information system laboratory facilities at STMIK Indonesia Padang are the computers that suddenly die when operated, the less cold room, display data is blurred, making the inconvenience in the learning process that causes the students less satisfied with the services provided. Students will feel satisfied if the service is expected to match the received. Therefore, a decision support system is needed to analyze the quality of services provided to the students so that it can support the role and function of the laboratory optimally and what attributes need to be improved the quality of service. The method used is Fuzzy Service Quality (Servqual) method. The results showed that the service quality received was not in accordance with the expected because there is a gap of -1.55 for tangibles dimension. Attributes that need to be improved the quality of services are laboratory space is cool and comfortable, the use of laboratories relevant to the field of science, the responsibility of laboratory assistant, the availability of professional teachers and attitudes and behavior of labor officers.

Abstrak
Laboratorium merupakan salah satu fasilitas pendukung dalam meningkatkan proses pembelajaran. Permasalahan yang ditemukan mahasiswa mengenai fasilitas laboratorium sistem informasi pada STMIK Indonesia Padang adalah komputer yang tiba-tiba mati saat dioperasikan, ruangan yang kurang dingin, data display yang buram sehingga membuat ketidaknyamanan dalam proses pembelajaran yang menyebabkan mahasiswa kurang puas terhadap layanan yang diberikan. Mahasiswa akan merasa puas apabila layanan yang diharapkan sesuai dengan yang diterima. Oleh sebab itu, diperlukan suatu sistem pendukung keputusan untuk menganalisis kualitas layanan yang diberikan kepada mahasiswa sehingga dapat mendukung peran dan fungsi laboratorium secara optimal serta atribut apa saja yang perlu ditingkatkan kualitas layanannya. Metode yang digunakan adalah metode Fuzzy Service Quality (Servqual). Hasil penelitian menunjukkan bahwa kualitas layanan yang diterima belum sesuai dengan yang diharapkan karena terdapat gap sebesar -1.55 untuk dimensi tangibles. Atribut yang perlu ditingkatkan kualitas layanannya yaitu ruangan laboratorium yang sejuk dan nyaman, penggunaan laboratorium yang relevan dengan bidang ilmu, tanggungjawab asisten labor, tersedianya tenaga pengajar yang professional dan sikap serta perilaku petugas labor

Kata kunci : sistem pendukung keputusan, laboratorium, fuzzy, servqual
Hareketli Ortodontik Aygıtları Temizleme Yöntemleri
Authors: AYDOĞAN Filiz , ŞENIŞIK Neslihan Ebru
Published: December 2018

Ortodontik tedavi sırasında ağız içine uygulanan hareketli aygıtlar basit diş hareketleri, fonksiyonel ortopedik tedavi, yavaş ve hızlı genişletme, pekiştirme ve yer tutucu amacıyla rutin olarak kullanılmaktadır. Ortodontik tedavi amacıyla hareketli aygıt kullanan hastalarda ağız bakımının yeterince sağlanamaması durumunda, aygıt yüzeylerinin kirlenmesi ve mikroorganizmaların bu yüzeylere tutunması kaçınılmaz olacaktır. Bu derlemenin amacı hareketli aygıtların temizlenmesinde ve dezenfeksiyonunda kullanılan mekanik ve kimyasal yöntemler hakkında bilgi vermektir.
Akut miyokard infarktüsünde yeni gelişen atriyal fibrilasyon ile SYNTAX skoru arasındaki ilişki
Authors: BAĞCI Ali , AKSOY Fatih , OSKAY Tülay , IŞIK İsmail Barkın , TÜRKER Yasin , OKUDAN Yunus Emre , ALTINBAŞ Ahmet , VAROL Ercan , KARABACAK Mustafa
Published: December 2018

Amaç: Atriyal fibrilasyon (AF) akut miyokard infarktüsü (AMİ)
sonrası en sık görülen ritim bozukluğu olup kısa ve uzun dönem prognozu olumsuz
yönde etkilemektedir. Koroner arter hastalığı (KAH) AF gelişimi için bağımsız
bir risk faktörüdür. SYNTAX (SYNergy between PCI with TAXUS and Cardiac Surgery) skorlama
sistemi, revaskülarizasyon öncesi, kantitatif ve tekrarlanabilir temel bir ölçüm
olması nedeniyle koroner anatomik ciddiyet ve karmaşıklığı gösterebilir.
Bilgimize göre SYNTAX skoru ile AF arasındaki ilişki araştırılmamıştır. Bu
nedenle AMİ ‘li hastalarda yeni gelişen AF ile SYNTAX skoru arasındaki ilişkiyi
araştırmayı amaçladık.

Metod: AMİ tanısıyla Ocak 2015-Haziran 2016 tarihleri arasında
kliniğimize yatırılan 350 hasta retrospektif olarak çalışmaya alındı.
Hastaların 273’ü (%78) erkekti. Hastaların 23 ‘ü dışlandı. Hastaların
demografik ve klinik özellikleri kaydedildi ve hastalar düşük SYNTAX skorlu ve
orta-yüksek SYNTAX skorlu olmak üzere iki gruba ayrıldı. SYNTAX skoru ile AF
gelişimi arasındaki ilişki değerlendirildi. AF gelişen hastaların bağımsız
belirteçleri çoklu regresyon analizine ile belirlendi.

Bulgular: Çalışmaya dahil edilen 327 hastanın 255’i (%77,8) düşük
SYNTAX skorlu iken 72’si (%22,2) orta-yüksek SYNTAX skorlu idi. Hastaların
37’inde (%10,6) takipte AF gelişti. Düşük ve orta-yüksek SYNTAX skorlu grupta
AF gelişme sıklığı benzer bulundu (%9,4’a karşılık %12,5, p=0,442). Çoklu
regresyon analizi sonucunda hastanede ADEİ başlanması (Olasılık oranı=0,362,
%95 güven aralığı 0,157-0,835, p=0,017), hastaların yaşı (Olasılık oranı=1,041,
%95 güven aralığı 1,008-1,075 p=0,014) ve KYBÜ’sinde yatış süresinin (Olasılık
oranı=2,911, %95 güven aralığı 1,595-5,315, p=0,001) AF gelişim riskiyle
bağımsız ilişkili olduğu saptandı.

Sonuç: AMİ hastalarında AF gelişimi ile SYNTAX skoru arasında
ilişki saptanmadı. Bu çalışmada yaş, yatış sonrası ADEİ başlanması ve KYBÜ
yatış süresi AF gelişimi ile bağımsız ilişkili olduğu gösterildi.
Púrpura de Henoch-Schönlein em adulto
Authors: Mello Jorge Luiz de Carvalho , Gallo Luis Paulo Cachola , Carvalho Kayane Ridolfi , Silva Juliana Monroe , Guimarães Sebastião Jupiaçara , Pereira Carolina Fernandes
Published: December 2018

A púrpura de Henoch-Schönlein (PHS) é uma vasculite caracterizada pelo depósito de imunoglobulina A (IgA) provocando reação leucocitoclástica. A etiologia não está totalmente esclarecida. Afeta principalmente crianças e o acometimento em adultos costuma ser mais raro e com pior prognóstico. Os locais mais afetados compõem uma tétrade: pele, articulações, trato gastrointestinal e rins. O diagnóstico é clinico, sendo que a maioria dos pacientes apresenta elevação sérica de IgA e a biopsia cutânea revela uma vasculite leucocitoclástica. Costuma ser uma doença benigna e autolimitada, a terapia de suporte base do tratamento é realizada com repouso e analgesia, além do uso de corticoide em casos mais intensos. Esse artigo reporta o caso da doença em um homem de 46 anos admitido com púrpura palpável, proteinúria, aumento do nível sérico de IgA e vasculite leucocitoclástica à biópsia cutânea. Foi tratado com corticoterapia, evoluindo com melhora expressiva do quadro.
Infecção em cicatriz de cesariana: revisão da literatura e relato de caso
Authors: Zimmermmann Juliana Barroso , Nunes Tatiana Dos Reis , Pereira Monique Policiano , Duarte Adrianne Maria Berno de Rezende
Published: December 2018

É apresentado o caso de uma puérpera que evoluiu com infecção de ferida operatória grave, sendo necessária internação e antibioticoterapia venosa. Não foi identificado nenhum fator de risco associado. Os autores relatam a importância do tratamento imediato para evitar complicações graves, como o óbito materno.
Má rotação intestinal na adolescência e suas consequências no diagnóstico tardio: relato de caso
Authors: Aragão Gislei Frota , Guedes Filho Ronaldo Sobreira , Colares João Henrique Freitas , Feijó Jamille Linhares , Oliveira Manuel Luiz Filgueira , Oliveira Yasmin Ingrid Santos
Published: December 2018

A má rotação intestinal é uma anomalia congênita de causa desconhecida, sendo vômitos biliosos um dos diagnósticos diferenciais na infância, e em adultos consiste em um difícil diagnóstico. Adolescente de 17 anos iniciou um quadro de dor mesogástrica, de caráter intermitente, com piora pós-prandial. Apresentou dores abdominais intensas, vômitos biliosos, desidratação e desnutrição severa. Foram realizadas endoscopia e seriografia digestiva alta, que sugeriram má rotação intestinal. O paciente foi submetido ao procedimento de Ladd por videolaparoscopia. Durante a cirurgia, foi achado o ceco em hipocôndrio esquerdo, estômago e primeira porção duodenal dilatada por presença de banda de Ladd na segunda porção duodenal. Foi realizado lise das bandas de Ladd, apendicectomia e reposicionamento das alças. Recebeu alta hospitalar após quatro dias. A má rotação intestinal em adultos é de difícil identificação e o procedimento de Ladd por videolaparoscopia é a técnica cirúrgica de escolha para esses pacientes sem complicações agudas.
Yönetsel Destek Algısının İşten Ayırma Niyeti Üzerine Etkisinde Ücret ve Ek Gelirlerin Düzenleyici Rolü: Konaklama İşletmeleri Örneği
Authors: Üstün Ferda
Published: December 2018

Bu araştırmanın amacı turizm işletmelerinde çalışanların yönetsel destek algılarının
işten ayrılma niyetleri üzerindeki etkisinde ücret ve ek gelirlerin düzenleyici rolünün
belirlenmesidir. Kapadokya bölgesinde faaliyet gösteren 4 ve 5 yıldızlı otel işletmeleri
çalışanları üzerine yapılan bu araştırmada bağımlı ve bağımsız değişkenler ile
düzenleyici değişkenin birbiri ile ilişkileri, ortaya konulan araştırma modeli ile
incelenmiştir. Araştırma sonucunda çalışanların yönetsel destek algıları ile işten ayrılma
niyeti arasında negatif yönlü; ücret ve ek gelirler ile işten ayrılma niyeti arasında ise
pozitif yönlü anlamlı ilişki tespit edilmiştir. Ayrıca çalışanların yönetsel destek algıları ile
işten ayrılma niyetleri arasındaki ilişkide ücret ve ek gelirlerin düzenleyici role sahip
olduğu görülmüştür.
Seyahat Acentalarında Müşterilerin Üretime Katılım Davranışının Algılanan Hizmet Çıktılarına Etkisi
Authors: Arıca Reşat , Kozak Rıdvan
Published: December 2018

Müşterilerle üretim,
işletmelere yeni fikirlerle iş yapma olanağı sunarken, müşterilerin özel
isteklerinin karşılanmasını sağlamaktadır. Bu durum, gerek işletmelerin sunduğu
hizmet çıktılarına gerekse müşterilerin algıladığı çıktılara etki etmektedir.
Bu noktadan hareketle hazırlanan araştırmanın temel amacı, seyahat
acentalarında müşterilerin üretime katılım davranışının algılanan hizmet
çıktılarına etkisinin belirlenmesidir. Araştırmanın verileri, seyahat
acentalarından üretime katılım yoluyla kültür turu satın alan ve İstanbul’u
ziyaret eden yerli turistlerden anket tekniğiyle toplanmıştır. Örneklemden
toplanan 425 geçerli anket verisi üzerinden gerçekleştirilen açıklayıcı faktör
analizi, doğrulayıcı faktör analizi ve yapısal eşitlik modellemesine ilişkin
sonuçlar, müşterilerin üretime katılım davranışının algılanan hizmet
çıktılarını doğrudan ve dolaylı olarak etkilediğini göstermektedir.
Müşterilerin üretime katılım davranışının algılanan turistik hizmet kalitesi ve
algılanan turistik değer üzerindeki doğrudan etkisi pozitif iken, müşteri
tatmini üzerindeki doğrudan etkisinin negatif olduğu sonucuna ulaşılmıştır.
Yiyecek İçecek Endüstrisinin Finansal Performansının Analizi: Türkiye ve Avrupa Ülkeleri Karşılaştırması
Authors: Karadeniz Erdinç , Beyaz Fatma Senem
Published: December 2018

Bu çalışmanın temel
amacı Türkiye’de ve Avrupa ülkelerinde faaliyet gösteren yiyecek içecek
işletmelerinin likidite, finansal yapı, faaliyet verimliliği ve karlılık
durumlarının karşılaştırmalı olarak oran analizi yöntemiyle incelenmesidir.
Türkiye yiyecek içecek endüstrisine ilişkin veriler Türkiye Cumhuriyet Merkez
Bankası’nın yayınladığı 2014–2016 dönemine ait endüstri ortalamalarından
yararlanılarak oluşturulmuştur. Avrupa yiyecek içecek endüstrisine ait finansal
oranların ortalamasının belirlenmesinde ise Avrupa’da faaliyet gösteren ve
sağlıklı verilerine ulaşılan, 40 adet yiyecek içecek işletmesinin finansal
durum ve kar-zarar tablolarından yararlanılmıştır. Analizde, oran analizi
yöntemi kullanılmıştır. Analiz sonucunda likidite, finansal yapı, faaliyet
verimliliği ve karlılık durumları açısından Avrupa’daki yiyecek içecek
endüstrisindeki işletmelerin Türkiye’deki yiyecek içecek endüstrisindeki
işletmelerden daha iyi bir performans gösterdikleri belirlenmiştir.
Computer Based Method to Automatically Identify the Regions of Intracerebral Haemorrhage on Diffusion Weighted Magnetic Resonance Images
Authors: Shanbhag Supriya Santosh , Udupi G. R. , Ranganath K.
Published: December 2018

In recent times several methods for automated diagnostic systems have been proposed to overcome the problems faced due to large number of patients, and the necessity of having high accuracy when dealing with a human life. Traditional way of examining the Diffusion Weighted (DW) brain images of the subjects with Intracerebral Haemorrhage (ICH) involves the inspection of specific features, by a human observer. Present work makes an effort to develop a computer based method to automatically identify the regions of ICH on DW brain images of the ICH subjects, and thereby help in transforming the conventional qualitative investigative criteria into a quantitative feature classification problem. In this direction feature extraction techniques, namely Discrete Cosine Transform (DCT) and Discrete Wavelet Transform (DWT) are employed to provide description of the significant properties of the DW brain images. Subsequently, K-Nearest Neighbor (KNN) method of image classification is employed to analyze the properties of the extracted features. The maximum classification efficiency of the KNN classifier for the correct output classification of the ICH subjects using DCT method is obtained as 71.50% for k value = 1.00, and using DWT method is obtained as 90.00% for k value = 9.00, respectively. Results imply that the technique proposed in the present work could positively be helpful in the fast diagnosis of the ICH subjects, even in the absence of a medical expert.
Faculty Development to Promote Effective Instructional Technology Integration: A Qualitative Examination of Reflections in an Online Community
Authors: Sullivan Roberta (Robin) , Neu Victoria , Yang Fengrong
Published: December 2018

The State University of New York Tools of Engagement Project (TOEP) < http://suny.edu/toep > is an online professional development model that encourages faculty and instructional support staff to explore and reflect on innovative and creative uses of emerging technologies through hands-on Discovery Learning Activities. TOEP is focused on creating peer-learning communities by providing a venue to experiment with the  evolving landscape of social media and the latest web-based technology tools. The concept of lifelong learning and how it relates to technology change serves as a guiding principle of this project. This research examines the reflective summary posts shared by participants in the project's online community to understand their perspectives about their experiences with TOEP. Our findings show that participants felt that they gained knowledge from the experiences of peers in the community. Many faculty stated that they integrated technology into their courses while they were participating in the project, or they expressed explicit plans to do so in the future. Many participants also expressed a desire to continue to learn about emerging technologies after their formal participation concluded.
Navigating assigned roles for asynchronous online discussions: Examining participants’ orientation using conversation analysis
Authors: Warren Amber N.
Published: December 2018

Asynchronous computer-mediated communication (CMC) tools, such as asynchronous online discussions (AODs), are widely used in higher education. Particularly for online-only classes the organization of AOD forums is of pedagogical importance, as these discussions are one of the major opportunities for participants to develop understanding of course content. This study examines participant orientations to a common AOD practice, assigning roles. The data were gathered from a graduate-level teacher education course that used forum discussion module included in Sakai. Using a conversation analytic perspective, data were examined to understand patterns in participants’ uptake of Discussion Starter and Devil’s Advocate roles in the forum. The findings demonstrate how assigning roles established a frame for participants’ understanding of course content and delimited possibilities for participation. Further, patterns of engagement related to these roles encouraged participants to distance themselves epistemically from the content of their posts. Specifically, students took up the Devil’s Advocate role in both expected and unexpected ways. While students did use this role as an opportunity to disagree with others in the forum, they also took up the role of Devil’s Advocate to pose non-critical questions as well. Pedagogical insights and the usefulness of conversation analysis as an analytical approach are discussed.