bluuebunny/crossref_metadata_2025 huggingface dataset:
Формирование фирменного стиля предприятия
Authors: Пьянова Наталия Викторовна , Алекса Елизавета Александровна , Попова Анна Ивановна , Лыгина Нина Ивановна
Published: March 2020

Цель: изучение технологии разработки фирменного стиля предприятия, формирования положительного фирменного стиля торговой компании и разработка рекомендаций по восстановлению имиджа фирмы. Обсуждение: в нынешнее время экономика в нашей стране активно развивается, создавая достаточно сложные условия выживания для торговых предприятий на арене конкурентной борьбы за потенциального покупателя. Потребителей интересуют надежные компании с серьезными и долгосрочными намерениями. По этой причине появляется необходимость в создании тщательно продуманного фирменного стиля предприятия, который уже сейчас является неотъемлемой частью деловой этики. Особенно значимы для фирмы поддержка и защита бренда, над которыми надо ежедневно работать, иначе компания может потерять лицо и клиентов. Следовательно, вопрос о роли фирменного стиля предприятия в конкурентной среде является одним из актуальных в современном мире. Методологическую базу исследования составили такие методы как анализ и систематизация теоретических положений по формированию имиджа предприятия, так и структурно-логического, системного подхода и другие. Результаты: Для достижения поставленной цели определено значение фирменного стиля, рассмотрены его элементы и основные этапы разработки, изучены виды рисков, которые могут навредить имиджу компании. Технология разработки фирменного стиля предприятия представлена в виде основных этапов его формирования и инструментов эффективного регулирования имиджа компании. Результаты исследования показали, что фирменный стиль компании – базис, эффективный инструмент маркетинговой политики, содействующий успешному развитию любой фирмы.
Особенности социально-экономических проблем моногородов Центрального Федерального Округа
Authors: Лавриненко Ярослав Борисович , Раевич Игорь Александрович
Published: March 2020

Цель: исследование региональных социально-экономических проблем моногородов Центрального федерального округа. Обсуждение: Центральный федеральный округ Российской Федерации традиционно относится к числу территорий, отличающихся высоким уровнем эффективности социально-экономических процессов и значительными темпами развития. В то же время на территории округа представлены самые различные локации, значительно дифференцированные как по экономическому потенциалу и инфраструктурным возможностям, так и направленности и тенденциям социально-экономической динамики, в том числе моногорода со специфическим набором проблем местного и регионального масштаба. Результаты: в результате авторского исследования социально-экономического положения 56 моногородов Центрального федерального округа был составлен балльный рейтинг, анализ которого позволяет выделить три рейтинговые группы: первую группу образуют 5 моногородов стабильным социально-экономическим положением; вторую – 42 моногорода с нестабильным социально-экономическим положением; третью – 9 моногородов с депрессивным и потенциально опасным социально-экономическим положением. Обосновано, что проведенное исследование должно быть дополнено исследованием настроений и ожиданий населения моногородов, поскольку это позволит более точно определить те проблемные зоны, которые нуждаются в первоочередном вмешательстве органов государственной власти.
Evaluación de programas de lengua: perspectivas profesionales e investigadoras
Authors: Ciller Julio , Ortín Ramsés
Published: March 2020

The purpose of this article is to advocate for the use of ongoing evaluative processes at the programmatic level in order to ensure language program quality and worth. After a thorough review of the field of language program evaluation, we argue that the benefits of evaluation cannot but strengthen the relationship between an academic program and stakeholders’ needs (students, teachers, community). We propose the use of the CEA standards as a guide for any evaluative effort in foreign language programs while designing context-specific tools to address the needs of each program. Finally, we aim to promote the development and dissemination of case studies, resources, and/or journals to enhance the status of language program evaluation within the field of applied linguistics.
Editorial
Authors: Nomdedeu Rull Antoni
Published: March 2020

El número 12 de la Revista Internacional de Lenguas Extranjeras (RILE) presenta cuatro estudios centrados en diferentes ámbitos de la enseñanza y aprendizaje de lenguas, trabajos en los que, como se indica a continuación de manera resumida, se abordan cuestiones de muy diferente índole: la enseñanza de los gestos emblemáticos en la competencia léxico-semántica: una propuesta para el aula de ELE; evaluación de programas de lengua: perspectivas profesionales e investigadoras; acercamiento empírico a las equivalencias de los verbos de desplazamiento en español y alemán; validación de materiales didácticos de ELE adaptados al contexto cubano
Investigating the effects of problem-solving method and cognitive flexibility on improving university students’ metacognitive skills
Authors: İDAWATİ İdawati , SETYOSARİ Punaji , KUSWANDİ Dedi , ULFA Saida
Published: March 2020

This study was aimed to investigate the effects of the problem-solving method on university students' metacognitive skills and cognitive flexibility levels. The research was modelled in a semi-experimental pattern, with experiment-control groups. According to the cluster sampling technique, 144 pre-service teachers who attended the Elementary Teacher School program in the spring semester of 2018-2019 had been determined as participants in Indonesia. Cognitive Flexibility Inventory (CFI) and Metacognitive Awareness Inventory (MAI) were used as data collection tools. An Independent Sample t-Test and descriptive statistics techniques were used in the analysis of the data. The discussion method, which is used more in university education, was employed in the control group, while the problem-solving method was employed in the experimental group. As a result of the research, it was found that there was a significant difference in the metacognitive skill levels of students with high cognitive flexibility when compared to those with low cognitive flexibility. This differentiation is in favor of students with a high cognitive level. Furthermore, a significant differentiation was observed between the metacognitive skill scores of the two groups where the discussion and problem-solving methods were applied. It was seen that this differentiation was in favor of the group with the problem-solving method. This study therefore recommends that instructional adaptations should be made to increase pre-service teachers' cognitive flexibility. Also, the problem-solving method can be used for the development of metacognitive skills. Thus, they can provide experiential knowledge during the university education process, in order to develop these two important features.
The eatablishment of chilling model for rhizome bud dormancy releasing in Polygonatum kingianum v1
Authors: Wang Yue
Published: March 2020

Polygonatum kingianumCollett & Hemsl. is an important traditional Chinese medicine [1]. However, several factors can inhibit the production of P. kingianumfollowing seed germination. One of these issues derives from the stages of early rhizome development, wherein the young germinated seed quickly develops a small rhizome that passes into a prolonged stage of bud dormancy, requiring a sustained period of cold for the initiation of additional growth and development. The current protocol is conducted to explore specific chill models for rhizome bud dormancy break in Polygonatum kingianum. In this study,rhizome buds were set at various chilling temperatures for different durations and then transferred to warm conditions for germination and subsequent evaluation of the temperature efficiencyand chill requirements.
A method for screening key genes through weighted gene coexpression network analysis (WGCNA) v1
Authors: Wang Yue
Published: March 2020

A flow for screening key genes through weighted gene coexpression network analysis (WGCNA)
An overview of asphalt pavement design for streets and roads
Authors: Vásquez-Varela Luis Ricardo , García-Orozco Francisco Javier
Published: March 2020

Pavements are geotechnical problems; consequently, a geotechnical framework is useful to describe their constitutive elements. The design of asphalt pavements for streets and roads evolved from empiric to mechanistic-empiric (M-E) procedures throughout the 20th century. The mechanistic-empiric method, based on layered elastic theory, became a common practice with the publication of separate procedures by Shell Oil, Asphalt Institute, and French LCPC, among others. Since its origin, the M-E procedure can consider incremental pavement design but, only until the beginning of the 21st century, the computational power became available to practicing engineers. American MEPDG represents the state-of-the-art M-E incremental design procedure with significant advantages and drawbacks, the latter mainly related to the extensive calibration activities required to assure a proper analysis and design according to subgrade, climate, and materials at a particular location and for an intended level of reliability. Perpetual pavements are a subset of M-E designed pavements with a proven history of success for the particular conditions where they are warranted. No design method, either the most straightforward empirical approach or the most elaborated incremental mechanistic one, is appropriate without proper knowledge about the fundamental design factors and calibration of the performance models for each distress mode upon consideration.
The Effects of Halofuginone and Ursodeoxycholic Acid in Prevention of Sclerosing Cholangitis Caused by Scolocidal Agents
Authors: YILDIRIM Doğan , AKTÜRK Okan Murat , KOCAKUŞAK Ahmet , ÇAKIR Mikail , SUNAMAK Oğuzhan , HUT Adnan , ZENGİN Abdullah Kağan , ÖZCAN Murat , AKI Hilal , BALCI Huriye
Published: March 2020

Aim: Biliary
sclerosis is a life treatening condition caused by auto-immunity, operative
trauma, toxic agents, cancer and chronic inflammatory conditions. The liver tissue may progress into overt cirrhosis
by the progression of fibrotic scar tissue. Halofuginone, which is the active component of the
plant alkaloid febrifugine, has been shown to inhibit fibrosis. Material and Method: Fifty rats were randomized
on 5 groups to form a biliary sclerosis model by a scolocidal agent povidone
iodine(PI) injection into the common bile duct with a control group of saline
infusion included. The four PI groups were later treated by halofuginone, ursodeoxycholic
acid (UDCA), with both and none. The rats were sacrificed 90 days later for intrahepatic
and hilar fibrosis. Laboratory parameters of liver damage and levels of
hydroxypryroline to show collagen degradation were obtained and histological
examination of the liver and the common bile duct for fibrotic changes were
carried out. Results: With or without application
of ursodeoxycholic acid, the halofuginone groups showed significantly less
sclerosis according to histological analysis. In regard to serum analysis of SGOT,
 SGPT and ALP; there were significant
differences between “PI only” group and halofuginone groups. GGT was significantly
high in “PI only” group. There was not any significant difference between the
groups in regard to bilirubin levels. Hydroxyproline serum levels were highest
in “PI only” group,  followed by “UDCA
only” group and then halofuginone groups.Conclusion: Halofuginone was effective
in preventing fibrosis as an additional medical therapy to UDCA in an induced
sclerosing cholangitis model in rats.
The Prototype of a Story Book Based Platform for Preschool Programming Education
Authors: Tseng Chun-Hsiung , Lin Jia-Rou , Chen Yung-Hui
Published: March 2020

The importance of learning how to program can never be over-estimated. Even though there are already programming-learning applications for young children, most of the applications in this field are designed for children in the elementary school age or even above. Teaching younger children, for example, preschool kids, how to program appears more challenging. From our survey, it appears that even preschool kids can understand how to do programming and the question is simply which tools to use. Preschool kids usually start their reading from picture books. They learn mathematics, arts, histories, and a lot of knowledge with picture books. The goal of this research is to propose a platform for story tellers, illustrators, and programming education experts to cooperate to build picture books to teach preschool kids how to program. At this very initial stage, the platform is developed as a Web application and hence it can be easily accessed by various devices via Web browsers. The platform consists of a lean story editor, a picture book editor, and a programming concept editor.
Escenarios en el logro de objetivos educacionales de alfabetización inicial en el nivel preescolar mexicano
Authors: Luna Peña Ana María , Mancilla Francisco Rocío Elizabeth
Published: March 2020

La educación formal es la respuesta a la necesidad de una práctica educativa ordenada y eficiente. En México, la Secretaría de Educación Pública es la institución encargada de ordenar la práctica educativa en todos los niveles del sistema educativo nacional. El currículo de preescolar, por su parte, ha sido definido por esta desde una perspectiva formativa, que no contempla que el niño egrese leyendo de manera convencional y autónoma. Aun así, las instituciones preescolares privadas de este país suelen solicitar a sus docentes que sean capaces de lograr que el niño egrese leyendo y escribiendo fluidamente. La presente investigación descriptiva ofrece un acercamiento comparativo de los factores implicados en el logro de objetivos educacionales de alfabetización en escenarios preescolares públicos y privados mexicanos. Se apoya en dos instrumentos, aplicados entre febrero y junio de 2018: un cuestionario a docentes y una entrevista a directores; estos cumplen el objetivo de responder: ¿cuál es el grado de percepción de logro que tienen los docentes de preescolares mexicanos de los objetivos educacionales relacionados con la alfabetización inicial de sus alumnos?, y ¿cuáles son las condiciones y requisitos que establecen las escuelas preescolares tanto públicas como privadas para el ejercicio de su práctica docente?
Textos poéticos y jóvenes lectores en la era de internet: de "Booktubers", "bookstagrammers" y "followers"
Authors: Quiles Cabrera Mª del Carmen
Published: March 2020

En el presente artículo ponemos de manifiesto cómo en la era de internet los nuevos espacios para la creación literaria adquieren una vital importancia en la formación de lectores. Las poéticas surgidas a través del blog, de las redes sociales y de las plataformas on line responden a un modelo de lectura multimodal que ha transformado el panorama literario en la actualidad. Este cambio social y tecnológico ha de tomarse en cuenta si pretendemos que nuestros estudiantes se aproximen a la poesía con interés y deleite. Será necesario, por tanto, abrir los textos del canon, salir del esquema historicista en la enseñanza de la literatura y encontrar en los entornos digitales vías para el tratamiento didáctico de los contenidos. Por tanto, consideramos que las aportaciones de booktubers, bookstagrammers y vídeo-poetas serán claves para tender puentes entre la literatura del canon y las nuevas formas de entender la escritura literaria, especialmente cuando nos encontramos ante un público milenial, que no concibe el mundo sin la comunicación en red y sin el contacto con los influencers del momento.
Lectura y oralidad en la escuela del siglo XXI. Materiales de enseñanza para las prácticas de lengua y literatura en el mundo digital
Authors: Tosi Carolina
Published: March 2020

El presente trabajo ofrece un abordaje en torno a la educación lingüística y literaria en el nivel secundario, apelando a los recursos que ofrecen las nuevas tecnologías de la información y la comunicación. En primer lugar, el análisis evidencia que actualmente el rol del docente se ha complejizado, ya que se desempeña como mediador entre los estudiantes, los libros impresos y las prácticas del ámbito digital, a la vez que se posiciona como administrador y guía en el uso de las herramientas virtuales. En este sentido, se caracterizan los recursos digitales como potenciales materiales de enseñanza, haciendo hincapié en los producidos en la Argentina. En tercer lugar, se demuestra la relevancia de géneros y soportes digitales para el abordaje de la práctica de la oralidad en la educación lingüística y literaria. Para ello, y a modo ilustrativo, se ofrece una serie de experiencias pedagógicas bosquejadas en cursos de capacitación para docentes y futuros docentes en la Argentina. Finalmente, y sobre la base de los estudios de Chartier (2015) y Goldsmith (2015), se deja planteado que la reflexión sobre el lenguaje y los estudios literarios se constituyen como un campo de conocimiento en plena “ebullición” y, atento a ello, el aula puede ser un espacio propicio, tanto para los docentes como para los estudiantes, para indagar y participar de esas transformaciones.
EGIDO GÁLVEZ, I.; MARTÍNEZ-USARRALDE, M.J. (2019). La educación comparada hoy. Madrid: Síntesis, 252 páginas, ISBN 978-84-9171-412-5
Authors: Espejo Villar L. Belén
Published: March 2020

EGIDO GÁLVEZ, I.; MARTÍNEZ-USARRALDE, M.J. (2019). La educación comparada hoy. Madrid: Síntesis, 252 páginas, ISBN 978-84-9171-412-5.
Cytomorphological spectrum of cervical smears in a tertiary hospital
Authors: H N Ashwini , Ramu Shwetha , H Bevinakatti Subhashini , T S Nagaraj , Patil S B
Published: March 2020

Cervical cancer is one of the leading causes of mortality and morbidity in women worldwide. Invasive cervical carcinomas are preceded by a stage in which the abnormal cells are confined to the epithelium (Intraepithelial stage). Women can be routinely screened for intraepithelial stage with cervical cytology smears and hence invasive stage can be prevented by early diagnosis. Cervical cytology smears also an useful tool in aiding the diagnosis of infectious and inflammatory conditions of the cervix.

To evaluate the cytomorphological spectrum of cervical smears referred to a tertiary hospital.

It is a retrospective observational study. Clinical data and pap smear cytology reports were obtained from the archives during the period of May 2018-May 2019(1 year study). All smears were reported as per “Bethesda system of reporting cervical cytology ” 2001.

A total of 1241 cases were examined. The age group of patients ranged between 18yrs to 75 yrs. A total of 1203 cases (97%) were reported as Negative for intraepithelial lesions/malignancy, out of which 124 cases(0.1%) showed vaginal candidiasis, 56 cases (0.05%) were reported as Trichomonas vaginalis infection, 321 cases (0.26%) as Bacterial vaginosis, 1 case of HSV infection associated changes, 67 cases(0.05%) were reported as inflammatory smears. 38 cases showed abnormality, out of which 29 cases were of ASC-US,3 cases of LSIL, 3 cases were reported as HSIL, 2 cases as Squamous cell carcinoma and 1 case with adenocarcinoma cervix.

Cervical inflammatory lesions (including infections) and neoplastic lesions (includes intraepithelial and epithelial malignancies) can be diagnosed by Cervical cytological smears.
A crystallization and preliminary X-ray diffraction study of the Arabidopsis thaliana proliferating cell nuclear antigen (PCNA2) alone and in a complex with a PIP-box peptide from Flap endonuclease 1
Authors: Kowalska Ewa , Strzałka Wojciech , Oyama Takuji
Published: March 2020

DNA replication is an important event for all living organisms and the mechanism is essentially conserved from archaea, bacteria to eukaryotes. Proliferating cell nuclear antigen (PCNA) acts as the universal platform for many DNA transacting proteins. Flap endonuclease 1 (FEN1) is one such enzyme whose activity is largely affected by the interaction with PCNA. To elucidate the key interactions between plant PCNA and FEN1 and possible structural change of PCNA caused by binding of FEN1 at the atomic level, crystallization and preliminary studies of X-ray diffraction of crystals of Arabidopsis thaliana PCNA2 (AtPCNA2) alone and in a complex with a peptide derived from AtFEN1, which contains a typical PCNA-interacting protein (PIP)-box motif, were performed. Both peptide-free and peptide-bound AtPCNA2s were crystallized using the same reservoir solution but in different crystal systems, indicating that the peptide affected the intermolecular interactions in the crystals. Crystals of AtPCNA2 belonged to the hexagonal space group P63, while those of the peptide-bound AtPCNA2 belonged to the rhombohedral space group H3, both of which could contain the functional homo-trimers.
HUMAN CAPITAL INVESTMENT (HCI) DETERMINANTS AFFECTING THE INSTITUTION’S PERFORMANCE: THE PRACTICALITY OF PARTIAL LEAST SQUARES STRUCTURAL EQUATION MODELLING (PLS-SEM) APPROACH
Authors: Akmal Mat Nawi Farahiyah , Malek A. Tambi Abdul , Faizal Samat Muhammad , Baistaman Julaina
Published: March 2020

Purpose of the study: This paper aimed to assess the analysis of the role of human capital investment (HCI) determinants and its remarkable contribution towards the education institution's performance by adapting the Malcolm Baldridge Criteria for Performance Excellence.

Methodology: This research adopted a quantitative study and a survey tool comprises of sixty items with seven Likert scale was utilized as an instrument to assemble data from 309 lecturers in UiTM Kelantan. Next to test the research hypothesis data were then analyzed using the Structural Equation Modelling approach on the SmartPLS3 platform.

Main Findings: The analysis demonstrated the influences of HCI determinants towards the UiTM performance. The coefficient of determination (R2) value of 66.9% suggested that the variance of institution performance could moderately be explained by the observed variables, namely knowledge, skill, and training. The result also indicates the highest positive significant value for skill towards performance with β=0.283, t-value= 1.981 and p<0.005. It is proven that a persistent skill development significantly contributes to the performance.

Applications of this study: The research finding is useful to help the Ministry of Higher Education (MOE) in Malaysia to identify the relevant determinants in improving human capital quality.

Novelty/Originality of this study: There were a lot of studies that were conducted involving higher education in Malaysia. But the only limited number of studies was conducted by scholars in assessing the main contribution of human capital investment factors towards the institution's success.
High-Fat-High-Fructose Diet Decreases Hippocampal Neuron Number in Male Rats
Authors: Kusumastuty Inggita , Sembiring Frinny , Andarini Sri , Handayani Dian
Published: March 2020

BACKGROUND: Consumption of foods and drinks high in energy, fat, and/or sugar beyond the recommended quantities can cause obesity, which triggers the incidence of brain nerve cell death related to oxidative stress, high levels of tumor necrosis factor (TNF)-α and triglycerides, and low high-density lipoprotein (HDL) levels. Progressive nerve cell death causes decreasing cognitive performance. This study aims to prove that an American Institute of Nutrition committee in 1993 (AIN-93M) diet modified with high-fat-high-fructose (HFHF) can decrease the number of hippocampal neurons. A decrease in the number of hippocampal neurons indicates progressive nerve cell death.METHODS: An experimental study using a post-test control group design was carried out using male Sprague Dawley rats. Samples were selected using simple random sampling to divide them into two groups, Group I was AIN-93M-modified HFHF diet (n=14) and Group II was AIN-93M standard (n=16). The number of visible neurons was measured in the hippocampus area of Sprague Dawley rats’ brains, stained with haemotoxylin and eosin (H&E) and scanned under 400x magnification. Neurons were counted in 10 visual fields using the "Cell_Count" application.RESULTS: The data were analysed by Pearson’s correlation test using SPSS. The results show that rats in Group I had a greater weight gain and fewer neurons than those in the Group II (p=0.023, r=-0.413).CONCLUSION: The consumption of foods high in fat and fructose can cause an increase in nerve cell death, as shown by the decrease in the number of hippocampal neurons.KEYWORDS: brain nerve cells, high fat, high fructose, increased body weight
Epithelial Cells Count and the Ratio of Leukocytes and Epithelial Cells as the Criteria to Determine Qualified Specimen for Community-Acquired Pneumonia (CAP)-causing Pathogens Identification
Authors: Dharmawan Ade , Karuniawati Anis , Sudarmono Pratiwi Pudjilestari , Lestari Delly Chipta , Rumende Cleopas Martin
Published: March 2020

BACKGROUND: Community-acquired pneumonia (CAP) is the most common infectious with serious rate of morbidity and mortality. Recent conventional method only described 30-50% of CAP etiology. Sputum specimen quality assessment is important to obtain an accessible CAP-causing pathogens identification.METHODS: This was a prospective descriptive study involving 100 specimens from CAP-diagnosed subjects in Budhi Asih Regional General Hospital inpatien tcare. We assessed three gram-staining criteria for specimen quality determination, and continued by bacterial identification.RESULTS: All specimens were qualified according to criteria II, while only 94 and 96 specimens were qualified according to criteria I and III, respectively. Sixty-five specimens could be identified by culture and pneumoCLART polymerase chain reaction (PCR) examination, and the 35 specimens remained unknown. Ten out of those 35 specimens were positive after analyzed by Acid-fast Bacilli (AFB) test. The pathogens we identified including Klebsiella pneumoniae (29.6%), Acinetobacter baumanii (10.2%), Enterobacter cloacae (4.6%), Pseudomonas aeruginosa (4.6%), Staphyloccocus aureus (4.6%), Moraxella catarrhalis (3.7%), Enterobacter aerogenes (2.8%), Escherichia coli (2.8%), Streptococcus pneumoniae (1.9%), Mycoplasma pneumoniae (1.9%) and Citrobacter koseri (0.9%).CONCLUSION: There were no significant differences among the three criteria for sputum specimen quality assessment, based on culture and pneumoCLART examination. We suggest that criteria II could be used to avoid many specimen rejections while good quality specimens still attained for accessible bacteria identification.KEYWORDS: community-acquired pneumonia, sputum, gram stain, pathogens, bacteria
Differentiation of Low-Grade and High-Grade Glioma Using the Combination of Conventional Magnetic Resonance Imaging and Apparent Diffusion Coefficient Value
Authors: Mulyadi Rahmad , Hatta Mochammad , Islam Andi Asadul , Murtala Bachtiar , Tammase Jumraini , Aman Reninda Ananda , Susanto Eka
Published: March 2020

BACKGROUND: The conventional magnetic resonance imaging (cMRI) and apparent diffusion coefficient (ADC) may have a role in predicting tumor grade for gliomas and may in turn assist in identifying tumor biopsy sites. In this study, we aimed to determine the added value of a joint approach of diffusion-weighted imaging (DWI) and cMRI to determine of low grade and high-grade glioma, compare to cMRI alone.METHODS: Data were collected from 56 glioma patients, who underwent examinations and received treatment at Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia, from the period of 2015–2018. Inclusion criteria was patients who underwent cMRI with a DWIADC sequence and patient that were diagnosed with glioma according to the histopathological results. Pathology reports of the imaging results were reviewed independently. A receiver operator curve (ROC) analysis assessed the predictive potential of cMRI and ADC values for low-grade and high-grade gliomas.RESULTS: Fifty-six subjects met the inclusion criteria. The combination of MRI and ADC values increased sensitivity (to 90%) and negative predictive value (to 92.9%), and also improved the negative likelihood ratio (to 0.14). However, the combination of MRI and ADC values had the highest area under the curve (78.6%) and sensitivity (78.6%), which was similar to the separated examination.CONCLUSION: The combination of ADC value and conventional MRI increases sensitivity in differentiating low-grade and high-grade glioma compared to separated examination.KEYWORDS: glioma, conventional MRI, ADC value
Specificities of measured polyvariance the seeds of Cucurbita pepo var. giramontia Duch. under climate changes in Pridnestrovie
Authors: Khlebnikov V. F. , Smurova N. V. , Balashova I. T.
Published: March 2020

Actuality. Industrial technologies of vegetable crops cultivation, including squash cultivation, a lot of attention is paid to the uniformity of seeds by morphometric traits as a condition allowing to use the precision technologies.The goal of the study is to determine specificities of measured polyvariance the seeds of Cucurbita pepo var. giramontia Duch. under changes of climate conditions in Transnistria.

Materials and methods. The studies were carried out at the experimental plot of Pridnestrovian State University (Tiraspol) in 2005-2012. Objects of studies – 5 lines (166/5; 19/84; 98/5; 5Б; 48/20) of squash. Morphometric traits of seeds: mass, width, length, thickness were evaluated in the sample of 100 seeds. Mass of the seed was evaluated with help of torsion scales with exactness to 0,001 g. Width, length, thickness were mesuared with microscope MBS-10 with exactness to 0,1 mm. squash plants were treated with water solutions of the preperation Micefit in concentrations 10 and 100 mg/l in the phase of "2-3 true leaves" and "6-7 true leaves", standard is water treatment.Meteorological conditions (temperature, amount of precipitation) the year of seed reproduction were characterized by the data of Tiraspol Agrometeorological Station. Hydrothermal regime the growing of squash plants was characterized by the hydrothermal coefficient (CHT) of Selyaninov.

Results. The nature of changes in temperature and precipitation over 7 years (2005-2012 periods) were reflected increased anomality of weather conditions in Transnistrian region. First of all, it concerns the quantity and the intensity of precipitation during the formation and maturation of squash seeds. Distribution decades of total precipitation and temperatures caused extremely uneven hydration: CHT variation ratio was 29.2-61.3%. Almost all periods of study were stressful for plants and led to the dimensional polyvariance of squash seeds. The variation of morphometric traits (coefficient of variation) is depended on changes in the hydrothermal regime of the growing season. It has a non-linear character and was genotypically caused. Applying the preparation Micefit had a significant effect on the manifestation of traits of squash seeds and its interaction with meteorological factors determined their modifying ability in the following order: mass (78,2%)→ length (56,6%)→ thickness (43,7%)→ width (40,4%).
Erratum to: “Anxiety and neurometabolite levels in the hippocampus and amygdala after prolonged exposure to predator-scent stress”
Authors: Shevelev O. B. , Tseilikman V. E. , Khotskin N. V. , Khotskina A. S. , Kontsevaya G. V. , Lapshin M. S. , Moshkin M. P. , Komelkova M. V. , Feklicheva I. V. , Tseilikman O. B. , Manukhina E. B. , Downey H. F. , Zavjalov E. L.
Published: March 2020

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Więzienne macierzyństwo kobiet z problemem alkoholowym
Authors: Matysiak‑Błaszczyk Agata , Jankowiak Barbara
Published: March 2020

Macierzyństwo kobiet pozbawionych wolności jest ważnym problemem społecznym, gdyż dotyczy nie tylko samej osadzonej, ale także jej dzieci i całej rodziny oraz sposobu funkcjonowania w zakładzie karnym. Problem ten jest szczególnie trudny, gdyż dotyczy nie tylko osadzonych będących matkami, ale równocześnie matkami uzależnionymi od alkoholu. W tej sytuacji rośnie ilość czynników obciążających rozwój dziecka oraz wyzwań stawianych przed placówką resocjalizacyjną. Sposób oddziaływania pomocowego w więzieniu powinien uwzględniać zarówno dobro matki, jak i dziecka. Wyniki prowadzonych badań wskazują, że u kobiet inaczej niż u mężczyzn przebiega proces kontaktu ze środkami psychoaktywnymi oraz że istnieją różnice międzypłciowe w konsekwencjach używania i nadużywania środków psychoaktywnych. Problemy związane z używaniem alkoholu są powszechne wśród kobiet pozbawionych wolności, a uzależnionych skazanych matek przybywa w populacji przestępczych kobiet i dziewcząt. Podstawowymi celami oddziaływań pracowników Domów Matki i Dziecka jest kształtowanie u osadzonych kobiet pozostających w tym czasie w sytuacji aktywnego macierzyństwa umiejętności społecznych roli matki zarówno w czasie, gdy przebywają one wraz z potomstwem w warunkach izolacyjnych, jak i gdy opuszczą zakład karny. Istotne jest także zapewnienie ich dzieciom bezpieczeństwa i warunków umożliwiających prawidłowy rozwój psychospołeczny i fizyczny przy uwzględnieniu ograniczeń związanych ze specyfiką przebywania w placówce zamkniętej.
Prawo do obrony w ramach procedury „Niebieskie Karty”
Authors: Soćko Michał
Published: March 2020

Przedmiotem artykułu jest analiza możliwości obrony podejmowanej w ramach procedury „Niebieskie Karty” przez osobę podejrzaną o stosowanie przemocy w rodzinie. We wstępie zarysowano powody wprowadzenia tej procedury na grunt ustawy o przeciwdziałaniu przemocy w rodzinie, w szczególności wskazując na niedoskonałości prawa karnego w badanym zakresie. Dokonano także analizy samej definicji przemocy w rodzinie oraz członka rodziny. W dalszej kolejności omówiono, jakie kroki prawne osoba podejrzana o stosowanie takiej przemocy może podejmować, żeby wykazać niezasadność postawionego jej zarzutu. Jest to o tyle istotne, że samo wszczęcie i prowadzenie procedury „Niebieskie Karty”, a tym bardziej ustalenie stosowania przemocy w rodzinie, może powodować dla osoby podejrzanej liczne, negatywne konsekwencje zarówno natury prawnej, jak i faktycznej. Procedura ta może bowiem bezpośrednio wpływać na takie kwestie jak orzeczenie o winie rozkładu pożycia małżeńskiego, a tym samym na prawo do alimentów, pozbawienia lub ograniczenia praw rodzicielskich, ustalenie i sposób wykonywania kontaktów z dziećmi czy chociażby postrzegania takiej osoby w środowisku zawodowym czy zakładzie pracy.
The experience of implementing the Intercollegiate Educational Robotics Olympiad within the framework of the Training of Trainers in Vulnerable Areas Project in Costa Rica
Authors: Fonseca Pedro , Hernández Irene
Published: March 2020

This article presents the experience of conducting the Intercollegiate Robotics Olympiad in 2017, as a result of the implementation of the project of the School of Computing of the National University of Costa Rica (UNA), called Trainers in Robotics for Colleges in Vulnerable Areas, which is developed jointly with the Costa Rican Institute of Drugs (ICD) and the Ministry of Public Education (MEP). In addition, the challenges developed by the executors of the project and the results obtained by the benefited students who participated in this event are announced. This is an inter-institutional project of Costa Rica, which is aimed at preparing instructors in the area of robotics at the secondary level, so that they can train their students in vulnerable regions of Costa Rica. In order to give their students the opportunity to occupy their free time in positive activities.
Factors Afecting Female Students Motivation Related to Enrollment and Retention in Information Technology Courses
Authors: Avelino Meirylane Rosa Emidio , Salgado Luciana Cardoso de Castro , Mochetti Karina , Bravo Raquel , Leitao Carla Faria
Published: March 2020

The difficulty of including women in a male dominated environment is a current problem, leading to important factors such as the role of women in society, whose rules were always imposed and created by men. Specifically in the Information Technology (IT) field, there have been a growing concern as projects are being created with the main goal of studying this issue and reverse it. This work explores what motivated undergraduate students of Computer Science and Information Systems courses of Fluminense Federal University (UFF) to choose this area and how they are experiencing the first years in college. This research was conducted with a qualitative methodology in order to understand the main fears and difficulties they had while choosing those courses and how they are dealing with a mostly male environment. Our results are based on activities from #include  project, organized by female professors at UFF to attract more girls to technology courses and to support undergraduate students already enrolled. The female students affect by the project show to appreciate how it is raising an important question about the gender gap and the issues they have faced since they chose a course in the IT field.
CLINICAL AND HEMOGLOBIN PROFILE OF MALARIA PATIENTS IN KARITAS HOSPITAL, SOUTHWEST SUMBA, PERIOD OF YEAR 2017
Authors: Johan Alvin , Natalia Audrey , Djauhari William , Effendi Rambu Farah
Published: March 2020

Malaria infections in high endemic areas are not pathognomonic and often show non-specific symptoms. The Southwest Sumba district is a high endemic area of malaria with the annual parasite incidence (API) of 14.48‰. The research conducted in this area was to identify the clinical and hemoglobin profile of malaria patients and to obtain comprehensive information on the clinical characteristics of malaria in a high endemic area of Southwest Sumba district. This is a descriptive cross-sectional study. The data was obtained from the medical record of malaria patients between  January 1st and December 31st, 2017 in Karitas Hospital, Southwest Sumba district. Inclusion criteria were patients with asexual stages of Plasmodium spp. on their Giemsa-stained thick and thin peripheral blood smears examination. Exclusion criteria were malaria patients with coexisting diseases and who had taken medication before admitted to the hospital. The total number of patients was 322 patients, 50.6% of the subjects were ≥ 15 years old and 59.3% were male. Among 322  patients, 133 subjects were treated as inpatients. The result shows that most infection was caused by a single infection of P. falciparum.  The most common clinical symptom was fever (98.4%), followed by headache, vomiting, cough, and nausea. The most common physical finding was the axillary temperature of > 37.5°C (87.6%) followed by anemic conjunctiva and hepatomegaly, which was mostly found in pediatric patients. The number of patients with hemoglobin level ≤ 10 g/dL was 129. The MCV <80 fL was found in 79% of patients with anemia. Severe malaria was found in 116 subjects in this study according to severe malaria criteria set by the Indonesian Ministry of Health. Study results were consistent with other existing studies from other high endemic areas in East Nusa Tenggara province.
Utilisation des huiles essentielles en alimentation des volailles. 1. Performances de croissance et règlementation
Authors: ALLEMAN F. , GABRIEL I. , DUFOURCQ V. , PERRIN F. , GABARROU J.F.
Published: March 2020

L’interdiction des antibiotiques comme facteur de croissance en élevage a dynamisé la recherche d’alternatives comme les extraits végétaux et en particulier les huiles essentielles. En aviculture, les huiles essentielles de thym, origan et romarin sont les plus étudiées. Leur composition en principes actifs est très variable, entraînant certainement une grande variabilité des réponses zootechniques. L’huile essentielle de thym semble favoriser le gain de poids, en particulier chez le poulet. Celle d’origan améliore l’indice de consommation et la vitesse de croissance chez le poulet de chair, et le taux de ponte et l’indice de consommation chez la poule pondeuse. Celle du romarin améliore aussi l’indice de consommation chez le poulet. Cependant, utilisées à forte dose, les huiles essentielles peuvent exercer des effets contraires. Toutefois, la consommation d’huiles essentielles aux doses utilisées (moins de 0,5 mg par kg de poids vif) ne dépasse pas le seuil de toxicité pour l’animal ou pour le consommateur.
Utilisation des huiles essentielles en alimentation des volailles.2. Hypothèses sur les modes d’action impliqués dans les effets observés
Authors: GABRIEL I. , ALLEMAN F. , DUFOURCQ V. , PERRIN F. , GABARROU J.F.
Published: March 2020

Les composants des huiles essentielles peuvent présenter différentes activités biologiques, i.e.antimicrobienne, antioxydante et stimulatrice de récepteurs spécifiques. Chez l’animal, leur action dépend de leur devenir dans l’organisme lors de leur consommation, puis de leur action au niveau de leurs cibles biologiques. Le site de leur absorption le long du tractus digestif peut être modulé par différents facteurs, tels que la composition chimique de l’aliment, leur mode de présentation (sous forme libre ou protégée par encapsulation) et la dose d’utilisation. Selon leur site d’absorption, ils peuvent agir à différents niveaux : pour les composants absorbés dès la partie supérieure du tractus digestif, ils peuvent avoir un effet systémique, et pour ceux persistant jusqu’en fin d’intestin grêle, ils peuvent avoir une action dans les contenus digestifs jusqu’au niveau de ce segment intestinal, puis de façon systémique après leur absorption. Les produits absorbés après modifications métaboliques au niveau du foie peuvent ensuite exercer une action au niveau des différents organes de l’animal. Après élimination au niveau des reins, et compte tenu des mouvements de reflux de l’urine vers les caeca chez les oiseaux, les composants issus des huiles essentielles pourraient agir au niveau de ces deux diverticules. Ils peuvent avoir un effet sur le microbiote digestif (précaecal ou caecal), sur les tissus de l’animal lui-même, c’est-à dire sur leur état d’oxydation, sur l’immunité en particulier l’inflammation, sur l’appareil digestif et ses fonctions digestives, sur le métabolisme animal, sur son système nerveux et son comportement. Ces composants ont donc un grand potentiel d’action, qui reste à explorer, pour pouvoir optimiser leur utilisation.
Les rôles des caractéristiques sensorielles des aliments dans le comportement alimentaire des ruminants domestiques
Authors: FAVREAU-PEIGNÉ A. , BAUMONT R. , GINANE C.
Published: March 2020

Pour évaluer les aliments et orienter leurs choix alimentaires, les ruminants utilisent les informations pré-ingestives (c'est-à-dire les caractéristiques sensorielles des aliments perçues avant leur déglutition) et les informations post-ingestives (c'est-à-dire les conséquences digestives et métaboliques expérimentées par les animaux après la déglutition). Des associations entre informations pré- et post-ingestives peuvent être apprises par les animaux, leur permettant ainsi d’éviter les aliments qui induisent des conséquences négatives et de sélectionner ceux qui induisent des conséquences positives. Les informations post-ingestives sont considérées comme étant le principal facteur influençant le comportement alimentaire des ruminants, alors que les caractéristiques sensorielles des aliments seraient utilisées uniquement pour discriminer les aliments et pour les associer aux conséquences post-ingestives lors de processus d’apprentissage. Cependant, les caractéristiques sensorielles jouent également d’autres rôles. Premièrement, certaines caractéristiques sensorielles possèdent une valeur hédonique qui influence l’ingestion, les préférences et l’apprentissage de la valeur des aliments indépendamment des conséquences post-ingestives immédiates. Deuxièmement, certaines caractéristiques sensorielles deviennent des indicateurs des conséquences post-ingestives après que leur valeur hédonique initiale a acquis une valeur positive ou négative via un apprentissage ou le processus évolutif. Ces caractéristiques jouent alors le rôle de signal permettant d’aider les ruminants à anticiper les conséquences post-ingestives et à améliorer leur capacité d’apprentissage des conséquences des aliments, en particulier dans des environnements alimentaires complexes. Les caractéristiques sensorielles des aliments pourraient être utilisées pour procurer un plaisir alimentaire aux animaux, augmenter la palatabilité des aliments et accroître la capacité d’apprentissage des animaux dans des situations alimentaires complexes, autant d’éléments de nature à améliorer leur bien-être et leur productivité.
Les élevages laitiers et le lait demain : exercice d’analyse prospective
Authors: PEYRAUD J.L. , DUHEM K.
Published: March 2020

Les auteurs soulignent dans l’introduction le risque inhérent à un exercice de prospective pour les élevages laitiers et le lait demain qui est tributaire de nombreuses variables peu maîtrisées. Ils rappellent les principaux atouts du lait, de l’élevage laitier et de la filière laitière française au regard des tendances de la demande mondiale, mais soulignent aussi les fragilités auxquelles la filière laitière, dans son ensemble, et la filière française en particulier, devra s’efforcer de répondre. Il s’agit à court terme des questions relatives à sa compétitivité mais également, l’érosion de son image et de son attractivité, son impact sur la santé de la population ou sur l’environnement. Un état des lieux de la situation actuelle est dressé, qui permet de souligner que tant les filières amont qu’aval se sont restructurées, et que cette tendance va se poursuivre, accompagnée d’une forte mutation du modèle social en production laitière. Les auteurs décrivent ensuite les principaux déterminants pour une filière durable, de l’amont à l’aval. Les axes de progrès majeurs pour le développement d’un secteur laitier compétitif et répondant aux attentes sociétales résident dans l’amélioration de l’efficacité de l’animal et du troupeau, l’autonomie et la sécurité de l’alimentation des troupeaux, l’amélioration des conditions de travail des éleveurs, une meilleure intégration des exploitations d’élevage au sein des territoires, une meilleure utilisation des innovations technologiques et organisationnelles, l’amplification des démarches de qualité, une veille et un « benchmarking » avec les pays et les secteurs concurrents notamment en termes d’innovation et un meilleur dialogue entre amont et aval pour l’adaptation du lait aux besoins de la transformation. En complément de ces actions clés pour assurer la durabilité de la filière laitière, d’autres pistes d’actions sont suggérées, dont l’élaboration d’une véritable stratégie de filière à même d’orienter les politiques publiques et de rapprocher les acteurs de la recherche-développement et de l’innovation.
Évaluation de l’utilisation de l’eau en élevage
Authors: CORSON M.S. , DOREAU M.
Published: March 2020

La pénurie d’eau, qui est le bilan entre sa disponibilité et sa consommation, est un problème régional avec des répercussions globales, car i) l’accroissement de la population humaine et de la demande en produits animaux entraîne l’augmentation de la demande en eau et ii) le changement climatique modifie les régimes de pluviométrie partout dans le monde. L’eau peut être divisée en eau « bleue » (eau de surface et des nappes phréatiques), en eau « verte » (eau du sol soumise à l’évapotranspiration) et en eau « grise » (eau virtuellement nécessaire pour diluer les polluants). Globalement 70% de l’eau bleue est utilisée pour l’agriculture. Une différence majeure entre méthodes d’appréciation de la consommation d’eau est l’inclusion ou non d’autres types d’eau que l’eau bleue. L’« empreinte eau » inclut les eaux verte et grise, alors que les analyses du cycle de vie tendent à les exclure, ou à inclure seulement la différence de disponibilité en eau verte en cas de changement d’utilisation des terres. Une seconde différence est la prise en compte de la consommation brute (en litres d’eau) ou pondérée par un index de stress hydrique (en litres d’équivalent-eau). En raison de ces différences méthodologiques, les estimations de la consommation d’eau pour un même produit varient fortement. En définitive, la pénurie en eau dépend de la consommation d’eau bleue. La contribution des animaux d’élevage à la pénurie en eau peut être réduite en diminuant leur consommation d’eau et/ou celle des cultures irriguées utilisées pour leur alimentation.