bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review on Collection of Herbs Used for the Treatment of Psoriasis
Authors: Krishna Rakam Gopi , Pravalika Kadagoni , Reddy, Nikhil , Sandhya Bhavani , Shrenitha Shrenitha , Aradhana Aradhana
Published: December 2024

The present study was aimed at collection of herbs
for psoriasis.Indian medicinal plants are gaining
popularity in treating several diseases. Due to the
availability of plants and less side effects people
are showing more interest in Indian medicinal
plants than other source of medications.Psoriasis is
an autoimmune disease that affects the skin. It is
characterized by changes in the skin that include
hyperkeratosis, parakeratosis. They can attribute to
an increased mitosis level in the basal region of the
epidermis, as well as disorders of maturing and
differentiating keratinocytes.Psoriasis is a common
and chronic disease with no cure.Psoriasis is an
inflammatory state of condition and aloe vera
mostly appears to have the anti-inflammatory
properties.The bioactive compounds may be
responsible for properties of all the plants that form
the basis of their use in herbal medicine in India.
Using herbal medicines and practicing herbalism
are currently fashionable trends. The most widely
used source of Indian herbs in the pharma industry
is because of their abundance. Some
phytoconstituents present in the plants are
responsible for treating Psoriasis.The use of herbal
products is expanding quickly worldwide as more
people become aware of their cost- effectiveness
and health benefits.This helps in supporting the
review and future research for future studies and
uses on different disorders faced due to various
reasons. Further investigation and research is still
required for the plants to explore various medicinal
properties.
Lepa Kalpana: Study on Ancient Preparation in Ayurveda
Authors: Rajesh Gupta Dr. Sneha , Mishra Dr. Brijesh
Published: December 2024

Ayurveda, an ancient science, harnesses natural
resources to achieve its core objectives of Swasthya
Rakshanam (maintenance of health) and Vyadhi
Prashamanam (treatment of diseases). Central to
Ayurvedic pharmacology are the branches of
Rasashastra and Bhaishajyakalpana, focusing on
drug manufacturing using herbal ingredients.
Bhaishajyakalpana encompasses various forms of
medicine preparation, including Panchavidha
Kashaya Kalpana such as Swarasa, Kalka, Shruta,
Shita, and Fanta, along with formulations like
Churna, Guti, Vati, Siddha Taila/Ghrita, Asava,
Arishta, and Lepa. Lepa, a semi-solid paste applied
externally, holds significance in treating diverse
ailments, especially those related to skin disorders
known as Kushta. The effectiveness of Lepa lies in
its ability to penetrate the skin surface, facilitating
optimal drug delivery. Despite its traditional use,
contemporary challenges such as odor, greasiness,
and time constraints have spurred research into
modifying Lepa formulations for enhanced efficacy
and prolonged shelf-life. This review consolidates
the historical significance, pharmaceutical aspects,
and modern adaptations of Lepa Kalpana,
underscoring its enduring relevance in Ayurvedic
medicine.
A Review on Herbal Cream for Treatment of Melasma
Authors: Ashok Lingayat Sumit , Ahmed Sameer Salam
Published: December 2024

Herbal medicine has a product of
worldwide importance of both medicinal and
economical. Although usage of this herbal
cosmetics has increased its quality, efficacy, safety,
cultural acceptability and lesser side effects are
concerned worldwide. Melasma is an acquired
hyperpigmentary disease that comes under
disorders of hyperpigmentation. The main purpose
of this literature review is how to tackle this
problem by using herbal cream containing
Glycyrrhiza Glabra Linn., Rubia Cordifolia Linn.,
and Calotropis Procera herbal extract for the
treatment of melasma.
Formulation and Development of Facecream using Borassus Flabellifer and Acalpha Indica
Authors: Karthika K Karthika K , Ragul B Ragul B , Swetha S Swetha S , Wishwaa J Wishwaa J , Wishwaa J Wishwaa J
Published: December 2024

This study aimed to develop a face
cream using natural extracts from Borassus
flabellifer (palmyra palm) and Acalypha indica
(Indian nettle) due to their skin benefits. Borassus
flabellifer is rich in vitamins, minerals, and
antioxidants that aid in skin nourishment,
hydration, and protection against oxidative stress,
while Acalypha indica has anti-inflammatory,
antimicrobial, and wound-healing properties
beneficial for treating acne and irritation. Active
compounds were extracted from both plants using
solvent extraction techniques and incorporated into
a cream base. Various formulations were created by
adjusting extract concentrations to find the optimal
combination for efficacy and stability, with
physicochemical properties such as pH, viscosity,
spreadability, and stability evaluated to ensure
quality and safety. Preliminary tests showed good
stability and maintained beneficial properties, and
in vitro studies indicated potential for enhancing
skin hydration, reducing inflammation, and
providing antimicrobial effects. Future in vivo
testing and consumer trials are planned to validate
the formulation's efficacy and safety. In conclusion,
the face cream with Borassus flabellifer and
Acalypha indica extracts shows promise as a
natural and effective skincare product, highlighting
the potential of traditional medicinal plants in
modern cosmetics.
Cutting-Edge Advances in Diagnostics and Treatments for Brain Diseases and Cancer
Authors: Prof. Laura S L Prof. Laura S L , R B Jay Sree , Dr. BlancheAJ Dr. BlancheAJ , Suganthi R Suganthi R
Published: December 2024

The brain is the most intricate organ. These organs
targets for numerous illness that result in
impairment and even death. These are the root
causes of various ailments, including cancer,
tumours, and so on. Cancer kills 10 million people
worldwide. Sensor based on nanomaterials that can
extract and identify circulating tumor cells, which
are tumor-specific biomarkers. Radiation
sensitization and photothermal therapy are used to
improve the therapeutic efficacy of Malignant
tumors. In this review, nanosensors application to
the diseases earlier and enhance the patient long
term survival
An Artificial Intelligence - Powered Evaluation of Aurantiamide as Inhibitor against Multiple Sclerosis
Authors: Yamuna V Yamuna V , Guhan G Guhan G
Published: December 2024

Multiple Sclerosis (MS) is a complex and
multifactorial disease characterized by chronic
inflammation, demyelination, and
neurodegeneration in the central nervous system
(CNS). Computer-aided drug design has gained
popularity and proven to be a useful tool for cutting
down on time and resources, especially in the early
stages of the drug development and discovery
process.The right enzyme target is found using the
SuperPred 3.0 platform. The SwissADME and the
Osiris property explorer are used for In-silico
ADMET evaluation. Protein repair and analysis
server (PRAS) is used to prepare proteins that were
retrieved from the RCSB databank. The webserver
CB-DOCK2 is used for active site prediction and
docking. The Biovia Discovery Studio is used to
visualise docking results. The Cabsflex 2.0 and the
fastDRH server are used for Molecular dynamics
and re-scoring computations, respectively.
According to the current study, Aurantiamide is a
non-toxic, orally accessible ligand that can
effectively inhibit certain receptors/enzymes in the
field of drug discovery. Aurantiamide may therefore
be regarded as a lead in the development of
medications. We also realised that the drug
discovery process is accelerated by AI-guided drug
design.
Formulation and Evaluation of Multivitamin and Antioxidant Herbal Chocolate
Authors: Gore Sonali A. , Harkal Ushaka S. , Gitte Pranavi P , Jadhav Vaibhav N , Munde Vedant B
Published: December 2024

The Chocolate is most loving food among the
people. It is an easiest form to chew and absorb for
every individual. ―The aim of the present study was
Formulation and evaluation of multivitamin and
antioxidant herbal chocolate‖ containing herbal
ingredients like ― Ocimum sanctum (Tulsi),
Zeylanicum cinnamomum (Cinnamon), Elettaria
cardamomum (Cardamom), Moringa oleifera, Beta
vulgaris (Beet root ), Saccharum officinarum
(Jaggery), The obroma cacao (Dark chocolate), are
the herbs and also contain other medicinal
properties like Antioxidant and Multivitamin.
Acute pericarditis: moderniz.
Authors: Bagul Rohit Santosh
Published: December 2024

Ongoing research has improved our current
understanding of acute pericarditis since the
publication of ESC guidelines on pericardial
diseases in 1915. This review provides information
on the most recent advancements in this area. Auto
inflammation has been added to the list of
causative mechanisms for recurrent acute
pericarditis, which helps to clarify the previously
vague diagnoses of "idiopathic" pericarditis.
Cardiac magnetic resonance can help direct
treatment in challenging patients by identifying
current pericardial inflammation. Creating risk
scores could help pinpoint patients with complex
pericarditis who require close monitoring and
aggressive treatment. The efficacy of IL-1
inhibitors in recurrent cases has been demonstrated,
showing a favorable safety profile. Recently, there
has been a growing interest in acute pericarditis
due to its occurrence as a possible side effect after
COVID-19 vaccination and its potential
complication in SARS-CoV-2 infection. Advances
in acute pericarditis have led to an improved
comprehension of the illness, enabling a
personalized approach for each patient.
Nevertheless, there are still unresolved queries that
necessitate additional investigation.
Microemulsions: A Paradigm Shift in Drug Delivery Systems
Authors: Kinge Ankit , Kohale Dr. Nitin , Yadav Prof. Suraj , Bisen Prof. Sonam , Dr. H.S.Sawarkar Dr. H.S.Sawarkar
Published: December 2024

A microemulsion is a transparent or nearly
transparent, quasi-homogeneous,
thermodynamically stable mixture of two
immiscible liquid stabilized by surfactant (or
mixture of surfactant). As pharmaceuticals drug
delivery systems, microemulsion have unique
properties, including clarity, high stability and ease
of preparation. Due to their physicochemical
properties, microemulsion often advantages over
traditional topical and transdermal drug delivery
systems. Moreover, microemulsion dispersion are
promising candidates as means for controlled drug
delivery, and as drug carriers for oral, topical, and
parenteral administration furthermore,
microemulsion have been shown to process
promising potential in the fields of cosmetic and
various consumer products. A brief overview
regarding the preparation, characterization and
application of microemulsion has been given in this
review article.
A Review on Transdermal Patch and Its Importance inDrugDelivary System
Authors: P.Vijayakumar P.Vijayakumar , P.Deenadhayalan P.Deenadhayalan , Narendiran .T Narendiran .T , Preamkumar.S Preamkumar.S , V Sneha.R Premalatha , Suji .S Suji .S
Published: December 2024

To address the challenges associated with oral drug
delivery, a transdermal drug delivery system was
developed. To deliver a specific dosage of
medication through the skin and into the
bloodstream, a transdermal patch is an adhesive
patch that has been medicated and applied to the
skin. This frequently encourages a body part that
has been injured to heal. The capacity to regulate
medicine to a understanding in a controlled way by
means of a transdermal fix is one advantage over
other strategies, such as verbal, topical,
intravenous, intramuscular, etc. Typically, this is
achieved by either a porous membrane enclosing a
drug reservoir or by body heat melting thin layers
of medication embedded in the adhesive. As a
result, only drugs whose molecules are small
enough to pass through the skin can be
administered via transdermal delivery systems.
This is the main drawback of these systems. The
preparation processes for several transdermal patch
types, including matrix patches, reservoir types,
membrane matrices, drug-in-adhesive patches, and
micro-reservant patches, are covered in this review
article. Furthermore, reviewed have been the
numerous techniques for assessing transdermal
dosage forms.
ASPECTOS EPIDEMIOLÓGICOS E ALTERAÇÕES LABORATORIAIS EM CÃES OBESOS
Authors: Junio Felicio Silva Thiago , Fagundes Guirra de Souza Jordana , Ribeiro Martins Isadora , Cândida Piveta Lidiana , Pacheco dos Santos Jandra
Published: December 2024

A obesidade tem sido considerada uma doença nutricional comum em cães nos países ocidentais, representando uma causa importante de diminuição da expectativa de vida dos animais de companhia. Essa é uma patologia de causas multifatoriais em que estão associados diferentes fatores de risco, como genética, idade, gênero e castração. Dentre os fatores ambientais, os hábitos de vida do tutor exercem grande influência na rotina dos animais, afetando principalmente o comportamento e a alimentação. Enfermidades endócrinas que acarretam alterações no organismo como hipotiroidismo, hiperadrenocorticismo, hiperinsulinismo e acromegalia são mais frequentes em cães obesos. Pesquisas identificaram alterações em exames laboratoriais, como maiores contagens de leucócitos totais e maiores concentrações de globulinas. O nível de colesterol, triglicérides e glicose sérica também ultrapassaram os valores de referências. Quanto à função renal, foi demonstrado o aumento de creatinina no sangue e na avaliação hepática houve diferença estatística na fosfatase alcalina e gama glutamil transferase entre cães saudáveis e obesos. Considerando a importância desse tema na atualidade, objetivou-se neste trabalho realizar uma revisão bibliográfica sobre aspectos epidemiológicos, doenças associadas à obesidade e alterações em exames laboratoriais de cães obesos.
El enfoque de la Investigación Acción Participativa (IAP) en el estudio de las problemáticas regionales
Authors: López Garay Hernán , Perdomo Pérez Mónica Tatiana , Henao Morales Laura Yamile , Gil Torres Ángel David , Rojas Salgado Maria Juliana , Uribe Sarmiento John Jairo , Salas Valdés Cristina , Rodríguez Fernández Iokine , Barros Navarro Nohora Isabel , Salamanca Santos María del Pilar , Santiago Andrés Padilla Quintero , Armijos Burneo María Teresa , Theuerkauf Ulrike , Mazorco Salas Julio Eduardo , Castillo Bohórquez María Isabel , Jiménez García David Leonardo , León Grimaldos Maria Victoria , Klaus Runge Andrés , Martínez Reséndiz Juana , Lopera Molano Daniel , López Garay Hernán
Published: December 2024

La Universidad de Ibagué está comprometida con el desarrollo regional. Ese es su lema fundamental. En la medida en que la región enfrenta problemáticas cada vez más complejas, honrar este compromiso demanda de la universidad, entre otras cosas, comenzar a cambiar radicalmente sus formas de producción de conocimiento y, por ende, los enfoques para investigar, comprender y ayudar a resolver dichas problemáticas. Este libro expone el trabajo de investigadores de la universidad (en algunos casos, en alianza con investigadores de otras universidades e instituciones) que han abordado mediante la IAP unas facetas problemáticas de nuestra región.
Eucalyptol (1.8-cineole) attenuates gentamicin-induced liver injury
Authors: Karataş Özhan , Kazak Filiz , Akçakavak Gökhan , Alakuş Halil , Abduljabbar Ahmed , Kırgız Ömer , Alakuş İbrahim , Kılınç Bahadır , Çelik Zeynep , Tuzcu Mehmet
Published: December 2024

Gentamicin (GM), which is in the aminoglycoside antibiotic class, is frequently preferred today in the treatment of diseases caused by gram-negative bacteria. However, its significant side effects on liver and kidney functions limit its clinical usefulness. The antioxidant and anti-inflammatory medical activities of eucalyptol (EUC, 1.8-cineole) have been reported in different studies. This study aimed to evaluate the effects of EUC on GM-induced hepatotoxicity. The study groups are consisted of control (C), EUC, GM and GM + EUC, and there were 7 rats in each group. At the end of the study, the rats were euthanized under appropriate conditions and samples were collected and biochemical, histopathological and immunohistochemical analyzes were performed. It was determined that there was a important increase in serum alanine aminotransferase (ALT), aspartate transferase (AST) and gamma-glutamyl transferase (GGT) enzymes in the GM group relative to the C group (p
SUSTAINABLE DEVELOPMENT, LABOUR RIGHTS AND COOPERATIVES: FROM THE UN RESOLUTION AND THE CSDDD TO THE PORTUGUESE COOPERATIVE LAW
Authors: Ribeiro María de Fátima
Published: December 2024

This paper analyses the relationship between the foreseeable changes that the approval of the CSDDD will bring to workers’ rights in commercial companies in the European Union and the necessary evolution of these rights in the context of cooperative law. In particular, attention is drawn to the need to introduce some changes to the Portuguese legal regime for the workers of the cooperative who, because they are not simultaneously its members, are not covered by the legal rules which are designed exclusively to protect the position of the latter.
LIMFODRENAŽINĖS KINEZIOLOGINIO TEIPAVIMO TECHNIKOS POVEIKIS VEIDO ODOS RODIKLIAMS
Authors: Barragan Ferrer Diana , Cambier Bernard , Mickienė Žaneta
Published: December 2024

Neinvazinės veido procedūros vis plačiau taikomos sprendžiant odos senėjimo problemas. Vienas iš nein­vazinių terapinių metodų, naudojamų šioje srityje, yra kineziologinis teipavimas. Kineziologinis teipas taiko­mas siekiant pagerinti kraujo ir limfotakos cirkuliaciją, sumažinti skausmą bei stimuliuoti fascijų, raumenų, raiš­čių, sausgyslių ir sąnarių veiklą. Taikant šį metodą, me­chanine jėga pakeliama oda, didinami poodinio audinio tarpai, taip skatinant nusilpusių raumenų stiprinimą ir užtikrinant odos atkūrimo procesą. Nors kineziologinis teipavimas vis dar nėra plačiai ištirtas ir pritaikytas odos priežiūros praktikoje, didėjantis susidomėjimas neinva­zinėmis procedūromis rodo šio metodo aktualumą veido odos senėjimo prevencijoje.

Šio tyrimo tikslas – įvertinti limfodrenažinės teipavimo technikos poveikį veido odos rodikliams. Tyrimo metu buvo atliktos penkios teipavimo procedūros, po kurių nustatyta, kad kineziologinis teipavimas teigiamai vei­kia veido odos viskoelastingumą, stangrumą ir sukelia vizualinius odos pokyčius.
5-12 METŲ VAIKŲ MAITINIMOSI ŠEIMOJE ĮPROČIAI
Authors: Žalnieraitienė Kristina , Dailidaitė Evelina , Viliušienė Ingrida
Published: December 2024

Vaikystėje įdiegti maitinimosi įgūdžiai išlieka ilgą laiką ir turi įtakos maitinimosi elgsenai ateityje, todėl svarbu tinkamus mitybos įpročius formuoti nuo mažų dienų.

Tyrimo tikslas. Atskleisti 5-12 metų vaikų maitinimosi šeimoje įpročius.

Metodika. Vienmomentinis tyrimas vykdytas 2024 m. kovo mėn. 13 – 28 dienomis. Naudotas duomenų rinkimo metodas – apklausa internetu (naudojant apklausų vyk­dymo platformą LimeSurvey). Tiriamieji – priešmoky­klinių bei pradinių klasių vaikus (5-12 m.) auginantys tėvai, kurių vaikai mokosi Kauno miesto mokyklose. Galutinei duomenų analizei naudoti 420 tyrimo dalyvių atsakymai. Surinkti duomenys buvo analizuoti naudojant SPSS duomenų analizės paketą.

Rezultatai ir išvados. Daugumos vaikų maitinimosi įpro­čiai nėra pakankamai geri: vaikai vartoja per mažai grū­dinių patiekalų, ankštinių daržovių bei žuvies. Per daž­nai vartoja saldumynus bei gaiviuosius gėrimus. Nors dauguma vaikų vartoja vaisius ir daržoves, jų vartojimo dažnumas bei kiekis nėra pakankamas. Nustatyta, kad sveikatai palankesni jaunesnio amžiaus vaikų (5- 6 m.) maitinimosi įpročiai lyginant su vyresniais (7-12 m.), bei vaikų, kurių tėvai įgiję aukštąjį išsilavinimą. Dažniau­siai taikomi sveikos mitybos įpročių ugdymo metodai – pokalbis su vaiku apie tai, kodėl reikia vaikams var­toti sveikatai palankius produktus bei vaiko įtraukimas į maisto produktų pirkimo procesą.
TAŠKINIO PĖDŲ IR PLAŠTAKŲ SAVIMASAŽO ĮTAKA STUDENTŲ MIEGO KOKYBEI BEI STRESO VALDYMUI
Authors: Janušauskaitė Monika , Borkertienė Vaida
Published: December 2024

Moksliniai tyrimai įrodė, jog studijų laikotarpiu studentai susiduria su sveikatos problemomis, tokiomis kaip per­vargimas, stresas, perdegimas ir nerimas [1,2]. Galima teigti, jog gera studento savijauta yra tiesiogiai susijusi su studijų rezultatais, psichologine gerove ir gaunamais pažymiais.

Nuo geros studento savijautos neatsiejama yra ir miego kokybė. Kokybiškas miegas yra būtinas normaliai pro­tinei veiklai, atminčiai ir mokymuisi. 2023 metais Vo­kietijoje atliktas tyrimas parodė, jog net 48,7 proc. (820 iš 1684 dalyvavusiųjų tyrime) studentų pagal Pitsburgo miego kokybės indeksą atitiko prastai miegančiųjų sta­tusą [3].

Tikslas − nustatyti taškinio pėdų ir taškinio plaštakų savi­masažo įtaką studentų miego kokybei ir streso valdymui.

Metodai. Atliktas kiekybinis tyrimas. Tyrimas buvo atlie­kamas du mėnesius, sesijos metu. Atrinkti 30 tiriamųjų, kurie atitiko atrankos kriterijus. Buvo vykdoma apklausa anketavimo metodu, naudoti du klausimynai – Pitsburgo miego kokybės indeksas (PSQI) ir Suvokto streso skalė (PSS-10). Apklausa buvo naudojama prieš pradedant savimasažo ciklą ir jam pasibaigus, norint gauti du re­zultatus palyginimui. Savimasažas taikytas 5 kartus per savaitę, po 20 minučių.

Išvados. 1.Taškinis pėdų savimasažas reikšmingai page­rino studentų miego kokybę ir streso valdymą. 2.Taški­nis plaštakų savimasažas taip pat reikšmingai pagerino studentų miego kokybę ir streso valdymą. 3. Tarp pėdų savimasažo grupės ir plaštakų savimasažo grupės rezul­tatų skirtumo nenustatyta.
MITYBOS ĮPROČIŲ POVEIKIS PAPRASTUOSIUS SPUOGUS TURINČIŲ ASMENŲ ODAI
Authors: Čapkauskienė Sandrija , Barragan Ferrer Diana , Mickienė Žaneta , Mikšėnaitė Evita
Published: December 2024

Apie 85 proc. paauglių ir suaugusiųjų patiria paprastųjų spuogų, vadinamų akne, problemą. Šią odos būklę gali su­kelti įvairūs veiksniai, tokie kaip emo­cinis stresas, deginimasis saulėje, netin­kamos kosmetikos naudojimas, hormonų pokyčiai ar net mitybos įpročiai. Įdomu tai, kad ilgą laiką mityba nebuvo siejama su aknės patogeneze, tačiau tyrimų rezul­tatai parodė, jog tam tikri mitybos pa­sirinkimai gali turėti poveikį aknės pa­sireiškimui arba paveikti jos gydymo veiksmingumą.

Tyrimo tikslas. Atskleisti paprastųjų spuogų turinčių vyrų ir moterų nuomonę apie mitybos įpročių poveikį odos būklei.

Metodika. Atliktas kiekybinis tyrimas, taikant anoniminę apklausą raštu. Tyrime dalyvavo 100 moterų ir vyrų. Pagrindinis atrankos kriterijus − paprastųjų spuogų pažeista oda.

Išvada. Dauguma respondentų mano, kad mitybos įpročiai yra susiję su spuogų pa­žeistos odos būkle.
PAAUGLIŲ NUOMONĖ APIE ODONTOLOGINIO GYDYMO BAIMĘ IR JĄ LEMIANČIUS VEIKSNIUS
Authors: Brundzienė Aurelija , Grūnovienė Danguolė , Mačiulienė Daiva
Published: December 2024

Tyrimo tikslas – atskleisti paauglių nuomonę apie odonto­loginio gydymo baimę ir ją lemiančius veiksnius. Tyrimo respondentai – 87 X pagrindinės mokyklos aštuntų kla­sių moksleiviai. Duomenų rinkimo metodas – anketinė apklausa. Duomenų analizės metodas – aprašomieji sta­tistiniai skaičiavimai (dažniai, vidurkiai). Tyrimo rezul­tatai atskleidė, jog daugiau nei pusė respondentų, atvykę vizitui pas gydytoją odontologą ir laukdami savo eilės, jaučia nerimą ir įtampą, o kai kurie – stiprų išgąstį, tik labai retais atvejais patiria atsipalaidavimo jausmą. Pa­grindiniai veiksniai, kurie respondentus verčia nemaloniai jaustis vizito pas gydytoją odontologą metu, yra adatos matymas ir dūrio jausmas, dantų gręžimo garsas, lauki­mas odontologinės klinikos priimamajame, kvapai bei gydytojo odontologo veiksmai. Respondentai nurodo, jog odontologinio gydymo baimė labiausiai siejasi su priežastimis jausti skausmą, būti kritikuojamiems dėl savo dantų būklės, nepakaks vieno vizito pas gydytoją odontologą. Absoliuti respondentų tėvų dauguma pasitiki gydytojais odontologais ir gydytojo odontologo padėjė­jais, bet dalis nurodo, jog odontologinio gydymo metu yra patyrę nemandagų gydytojo odontologo elgesį. Šei­mos palaikymas daro įtaką paauglio emocinei ir dvasi­nei savijautai, skatina pasitikėjimą savimi, apsaugo nuo streso ir nerimo.
PRIEŠMOKYKLINIŲ IR PRADINIŲ KLASIŲ MOKINIŲ SU BURNOS SVEIKATA SUSIJUSIOS ELGSENOS IR ŽINIŲ VERTINIMO INDEKSŲ ADAPTAVIMAS
Authors: Tamulienė Rasa , Mačiulienė Daiva
Published: December 2024

Straipsnyje pristatomo tyrimo tikslas – adaptuoti su bur­nos sveikata susijusios elgsenos ir burnos sveikatos žinių indeksus, skirtus priešmokyklinio ir pradinio mokyklinio amžiaus vaikams. Indeksai buvo adaptuoti pagal Buunk‐ Werkhoven ir kt. [2] sukurtus su burnos sveikata susi­jusios elgsenos (angl. Index for Oral Health Behaviour, OHB index) ir burnos sveikatos žinių (angl. Index for Oral Health Knowledge, OHK index) indeksus, taikant Delphi metodą. Adaptuotas su burnos sveikata susijusios elgsenos indeksas yra sudarytas iš septynių kriterijų: 1) dantų valymosi dažnumo; 2) paros meto, kuriuo valomi dantys; 3) spaudimo jėgos valant dantis; 4) dantų valy­mosi trukmės; 5) dantų valymosi judesių; 6) dantų pastos tipo; 7) liežuvio valymo. Adaptuotas burnos sveikatos žinių indeksas yra sudarytas iš 16 teiginių apie vaikų burnos sveikatą, apimančių tėvų žinias apie vaikų indi­vidualią burnos higieną, mitybos įtaką vaikų burnos svei­katai ir bendrąsias tėvų žinias apie vaikų burnos sveikatą. Sukurti indeksai gali būti naudojami tyrėjų, visuomenės sveikatos bei burnos priežiūros specialistų, siekiant įver­tinti esamą vaikų su burnos sveikata susijusią elgseną bei žinias apie vaikų burnos sveikatą ir planuoti vaikų burnos sveikatos gerinimo profilaktikos programas.
SLAUGYTOJŲ PROFESINĖS AUTONOMIJOS PANAUDOJIMO GALIMYBĖS TEIKIANT BŪTINĄJĄ MEDICINOS PAGALBĄ
Authors: Smaidžiūnienė Dalė , Ribaitienė Rita , Juozapavičienė Rasa
Published: December 2024

Profesinė autonomija, susijusi su sprendimų priėmimu, yra svarbi kokybiškos sveikatos priežiūros praktikos įgy­vendinimui. Slaugytojas gali jaustis profesionaliai nepri­klausomas, bet jam gali trūkti galimybių savo autonomiją panaudoti praktikoje. Tą lemia išoriniai (organizaciniai, darbo aplinkos, bendravimo darbe, gydytojų požiūrio ir kt.) bei vidiniai veiksniai (slaugytojo kompetencija, as­meninės savybės, nuostatos ir pan.). Profesinė autono­mija apima ne tik savarankišką, laisvą, nepriklausomą klinikinių sprendimų priėmimą pagal savo kompeten­ciją, bet ir slaugos praktikos kontrolę (net ir dalyvavimą tobulinant teisinį slaugos reglamentą) bei atsakomybę už savo darbą. Profesinės autonomijos įgyvendinimas leidžia slaugytojams lavinti profesinius įgūdžius, anali­zuoti, reglamentuoti, tobulinti slaugos praktiką, rūpintis pacientų gerove. Teikdami būtinąją medicinos pagalbą, slaugytojai turi greitai priimti sprendimus kintant klini­kinei situacijai, kartais neesant gydytojo, todėl aukštas slaugytojo autonomijos lygis padeda efektyviai dirbti, netgi turint ribotus žmogiškuosius išteklius. Priėmimo ir skubiosios pagalbos skyriuose slaugytojų autonomija įgalina juos efektyviai valdyti kartais sunkiai kontro­liuojamus ūminių pacientų srautus, produktyviai veikti komandoje, atstovauti paciento interesams net tada, kai išsiskiria specialistų nuomonės dėl sunkios būklės paci­entų priežiūros.

Tikslas – atskleisti slaugytojų profesinės autonomijos panaudojimo galimybes teikiant būtinąją medicinos pa­galbą. Tyrimas buvo vykdomas taikant kiekybinę ir ko­kybinę tyrimo strategijas. Tyrime dalyvavo 132 įvairių profilių slaugytojai.

Rezultatai. Dauguma slaugytojų patiria vadovų ir orga­nizacijos palaikymą, kai kalbama apie jų profesinę au­tonomiją darbe. Beveik 70 proc. respondentų visiškai arba iš dalies sutiko, kad teikdami būtinąją medicinos pagalbą, turi galimybę savarankiškai priimti klinikinius sprendimus, atitinkančius jų kompetenciją.

Nustatyta, kad beveik pusės slaugytojų, teikiančių būtinąją medicinos pagalbą, autonomijos lygmuo yra aukštas, tačiau daugiau nei trečdalio – žemas. Slaugy­tojų autonomišką elgseną darbe labiausiai stabdo nepa­laikanti darbo aplinka, baimė suklysti, žinių trūkumas ir gydytojų palaikymo stoka.
Google Drive as Instructional Media to Facilitate Students’ Assignment Submission: Opportunities and Challenges
Authors: Andi Bulkis Magfirah Mannong
Published: December 2024

In the 21st century of learning, the usage of technology has become an important role in education. Google drive, as media in collecting assignment, is able to improve the effectiveness and efficiency of student assignment management. This study aims to explore the use of Google Drive in the submission of student assignments in English language learning. This study used a descriptive qualitative method by using questionnaire as a technique in data collection. The subjects of this study were 50 English department students. The results showed that besides assisting students in assignment collection management and increasing technological literacy, the use of technology also helps improve student collaboration and independent learning.   However, it also found that the challenges faced by the students are not only related to accessibility, but also the lack of understanding Google Drive features, thus it makes some students are errors in uploading assignments. This study concluded that Google Drive can help to improve the quality of English language learning with some adjustments related to technical constraints and understanding of Google Drive features need to be overcome to make the assignment collection process goes smoothly and effectively.
الاستثمار في راس المال الفكري ودوره في تحسين جودة الخدمة الجامعية وفقا لانموذج التميز الاوروبي
Authors: علي شيرين نوري عزيز
Published: December 2024

يهدف هذا البحث لتحديد الى اي مدى يؤثر راس المال الفكري في تحسين جودة الخدمة الجامعية وفق انموذج التميز الاوربي وذلك عبر تقديم انموذج مقترح واختبار صلاحيته باستخدام النمذجة الهيكلية ، ثم اختبار العلاقات عن طريق تحليل علاقات الارتباط والتاثير بين المتغيرات  المتغير المستقل تمثل بـ( راس المال الفكري) ، والمتغير المعتمد تمثل بـ (جودة الخدمة الجامعية) ، وتم تطبيق ذلك في الميدان الجامعي على عينة من الاساتذة الجامعين ، واستخدم البحث المنهج التحليلي وفق اسلوب النمذجة البنائية ،  وقد تم التوصل الى مجموعة من الاستنتاجات اهمها دور ايجابي لراس المال الفكري في تحسين جودة الخدمة الجامعية وان تبني الاستراتيجيات وفقا لمعايير الاداء المؤسسي لانموذج التميز الاوربي يشكل عاملا مهما قادرا على الاستجابة لمتطلبات المجتمع المعاصر ويحقق رؤية قادرة على التعامل مع التحديات
A Note on Lie Algebra of Killing Vector Fields of Locally Rotationally Symmetric Bianchi Type-I Spacetime in f(Q)-Gravity
Authors: Alam Fakhar , Ramzan Muhammad , Khokhar Muhammad Arslan Rafiq , Ali Sajid , Kashif Muhammad , Batool Sofia
Published: December 2024

The goal of this paper is to derive the Lie algebra of Killing vector fields for the locally rotationally symmetric Bianchi type-I spacetime within the framework of f(Q) gravity, where f(Q) gravity is a modified gravitational theory that extends General Relativity by introducing a function of the non-metricity tensor Q to explore alternative models of gravity. To achieve this, various algebraic methods and direct integration techniques are employed. Different metric functions are analyzed, and the associated Killing vectors are determined for each case. It is observed that the spacetime under investigation can support either4, 6, or 10 Killing vector fields.
Assess Maternal Outcomes During Labor and the Immediate Postpartum Period in Overweight Mothers
Authors: Ali Dr. Farzana , Khanam Dr. Sifat Ara , Morshed Dr Muhammed Khaled , Das Dr. Deepa , Afroze Dr. Sayma , Farzana Fatema Akter
Published: December 2024

Background: Maternal obesity in pregnancy is generally recognized as one of the most common risk factors for unfavorable maternal and neonatal outcomes. Obesity has become a prominent issue in obstetrics practice. Objective: To evaluate the maternal outcomes during labor and the immediate postpartum period in overweight mothers. Materials and Methods: This cross sectional analytical study was conducted on the admitted patients with full term singleton pregnancy in labour in the Department of Obstetrics & Gynecology of Sir Salimullah Medical College and Mitford Hospital from July 2020 to January 2021. A total of 150 pregnant women with full term singleton pregnancy in labour were selected fulfilling the inclusion and exclusion criteria. Informed written consent was taken from each respondent. All data relevant to variables of the study was collected in a data collection sheet. Results: Caesarean section rates were considerably higher in overweight/obese patients compared to the normal weight group (p=0.002). The overweight/obese group had atonic PPH (p=0.04). Macrosomia neonate was substantially higher in the overweight/obese mother group than in the normal weight group (OR=10.09, p=0.009). Overweight/obese individuals had significantly increased rates of low APGAR scores (<7 at 1 minute) (p=0.041). The overweight/obese group had slightly increased rates of intrauterine mortality, stillbirth, and low APGAR score (<7 at 5 minutes), although the differences were not statistically significant (p=0.315, p=0.311, and p=0.190). Macrosomia necessitated neonatal critical care, and moms who were overweight or obese had a 4.03 times higher risk (OR=4.43, p=0.026). The obese neonates had a substantially higher mean birth weight (3.22±0.54 kg) compared to the control group (2.95±0.46 kg). Conclusion: Postpartum pregnancy problems such as atonic PPH have been described in overweight or obese pregnant mothers. Increased birth weight, stillbirth, macrosomia, and NICU hospitalizations were also identified in the overweight/obese population.
Econometric Analysis on Unemployment, Inequality and Economic Growth in India
Authors: Bhowmik Dr. Debesh
Published: December 2024

In this paper the author tried to find out the long run association between unemployment rate, GDP growth rate and income inequality in the post independent period in India from 1951 to 2023 by applying cointegration and vector error correction model. The paper found out that there is one cointegrating equation among the three variables where VECM implies that the change of unemployment rate and GDP growth rate is inversely related while the change of unemployment and the change of income inequality is positively related in the long run. The former is significant and the latter is insignificant in case of cointegrating equation which is convergent towards equilibrium with a speed of adjustment of 2.4% per year. There is short run causality between unemployment rate, GDP growth rate and income inequality. The VECM is stable and non-stationary having autocorrelation and multivariate normality problems.
Prescrição do exercício físico e combate ao estresse - 2ª Parte
Authors: Madureira Alberto Saturno , Madureira Janete Maragno
Published: December 2024

Este estudo tem como objetivo apresentar fundamentos teóricos e práticos para a prescrição de exercícios físicos como ferramenta de combate ao estresse, enfatizando os benefícios psicofisiológicos da atividade física. A pesquisa explora a relação entre atividade física, saúde e bem-estar, fundamentando-se em modelos teóricos de aptidão física e saúde, como os propostos por Shephard, Guedes e outros. São destacados os princípios de prescrição do exercício, incluindo frequência, intensidade, duração e tipo de atividade, enfatizando a importância da individualidade biológica. O estudo também aborda o impacto positivo do exercício na redução do estresse, por meio da distração, aumento da sensação de controle e interação social, além das mudanças fisiológicas promovidas pela atividade física. A prescrição de exercícios físicos é uma estratégia eficaz para mitigar os efeitos negativos do estresse, promovendo saúde mental e qualidade de vida. No entanto, é crucial que a prescrição seja individualizada e baseada em princípios científicos sólidos para maximizar seus benefícios. O estudo conclui que a atividade física, aliada a práticas saudáveis, desempenha um papel central na promoção da saúde e bem-estar.
Sobrepeso e obesidade: uma análise de crianças de 6 e 7 anos, no município de Marechal Cândido Rondon/Pr
Authors: Rangel José Nunes
Published: December 2024

Este estudo caracterizou-se como uma pesquisa descritiva, que teve por objetivo analisar a ocorrência de sobrepeso e obesidade em criança na faixa etária de 6 a 7 anos com peso acima do normal, no Município de Marechal Cândido Rondon- PR. A amostra constituiu-se de 221 escolares matriculados na primeira série do Ensino Fundamental do referido Município, sendo 108 crianças do sexo masculino e 113 do sexo feminino. Utilizou-se para diagnosticar a Estado Nutricional dos escolares, o critério proposto por Waterlow, sugerido pelo Comitê de Saúde Escolar da Sociedade Brasileira de Pediatria, o qual considera os índices peso para altura e altura para idade, utilizando-se como referencial o padrão do NCHS e a aplicação de um questionário para verificar alguns fatores ambientais dos escolares analisados. De forma geral, constatou-se altos índices de sobrepeso e obesidade principalmente nas crianças do sexo feminino. Com base nos resultados e nas informações extraídas do questionário, presume-se que tais índices se devem à alimentação inadequada, a falta de controle alimentar por parte dos responsáveis e à inatividade física.
Analisis Perubahan Kekerasan Material Terhadap Pembubutan
Authors: Ber Budi Wicaksono  , Rosehan  , Harto Tanujaya
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pengaruh kecepatan potong (Vc) terhadap kekerasan (Hb) material dalam proses pembubutan. Metode penelitian melibatkan pengujian kekerasan material pada berbagai kecepatan potong yang telah ditentukan. Hasil penelitian menunjukkan bahwa kecepatan potong memiliki pengaruh signifikan terhadap kekerasan material. Semakin tinggi kecepatan potong, semakin tinggi nilai kekerasan yang dihasilkan. Nilai kekerasan tertinggi yang diperoleh adalah 203.23 Hb pada kecepatan 175.84 m/min, sedangkan nilai kekerasan terendah adalah 174.2 Hb pada kecepatan potong 203.23 m/min. Perubahan kekerasan ini disebabkan oleh perubahan deformasi dan pengaruh dari gaya geser yang terjadi selama proses pembubutan. Kesimpulan dari penelitian ini menunjukkan bahwa pemilihan kecepatan potong yang tepat sangat penting dalam mengoptimalkan kekerasan material dalam proses pembubutan.
Pengaruh Variasi Arus Resistance Spot Welding Terhadap Kuat Tarik Material Stainless Steel 304 Carbody Kereta K1
Authors: Widya Prasetya Henry , Isti Pratiwi Damar , Izza Samudra Sello
Published: December 2024

Dalam proses manufaktur carbody kereta pada bagian side wall saat ini banyak menggunakan material pelat stainless steel 304 tebal 2 mm dengan metode resistance spot welding (RSW). Metode RSW memiliki kelebihan yaitu bentuk sambungan rapi, proses cepat, tidak memerlukan logam pengisi dan biaya murah. Namun, ditemukan beberapa cacat las RSW pada kereta stainless steel. Penelitian ini bertujuan untuk mengurangi cacat pada permukaan las RSW dengan variasi arus pengelasan dan menambahkan pengujian kekuatan tarik untuk mengetahui pengaruh weld nugget yang terbentuk. Metode dalam penelitian ini yaitu eksperimental. Parameter pengelasan RSW yang digunakan adalah variasi arus pengelasan 8 kA, 9 kA, 10 kA, 11 kA, dan 12 kA, waktu lama pengelasan konstan 2 detik, serta menggunakan elektroda tembaga diameter 16 mm. Selanjutnya dilakukan proses pengelasan spesimen. Setelah proses pengelasan, dilakukan pengujian penetrant dan pengujian tarik spesimen. Hasil dari pengujian penetrant didapatkan cacat permukaan pada penggunaan variasi arus yang semakin tinggi akibat proses pendinginan yang tidak sempurna. Hasil kekuatan tarik tertinggi didapatkan dari penggunaan variasi arus pengelasan 12 kA dengan kekuatan tarik sebesar 47,763 N/mm² dan pengujian tarik terendah didapatkan pada penggunaan variasi 8 kA dengan pengujian tarik sebesar 22,345 N/mm². Hal ini disebabkan oleh diameter weld nugget yang terbentuk pada variasi 12 kA semakin besar maka semakin besar kekuatan tariknya.
PRODUCTION PRACTICES, TRENDS, CONSTRAINTS AND OPPORTUNITIES OF BEEKEEPING IN ARBA MINCH ZURIA DISTRICT, SOUTHERN ETHIOPIA
Authors: ANZA Alemayehu , YEMAN Nebiyu
Published: December 2024

The economic potential of beekeeping within rural communities is substantial. This research endeavors to explore the landscape of beekeeping practices, honey production trends and the associated challenges and opportunities within the Arba Minch Zuria District, Gamo Zone, Southern Ethiopia. Selected purposively for its beekeeping potential, the district was stratified into three agroecological zones. Seven representative kebeles were proportionally chosen based on their agroecological diversity, and 156 beekeepers were systematically sampled. Utilizing formal surveys, a cross-sectional analysis employing one-way ANOVA and cross-tabulations was conducted. Results underscored mixed crop-livestock farming as the prevailing livelihood strategy, accompanied by traditional beekeeping being the most practiced method, with 96.8 % of the beekeepers employing traditional techniques. The average honeybee stocks per household were 4.8 ± 1.78 and 5.2 ± 6.98 colonies for traditional and modern beehives, respectively. Correspondingly, the average honey yield was 5.8 ± 0.09 kg and 20.1 ± 0.31 kg per year for traditional and modern beehives, respectively. Over the last five years (2014 − 2018), there was a decreasing trend of total colony number and honey yield. While beekeepers face challenges such as a shortage of bee forage, absconding and honeybee enemies, there are ample opportunities such as numerous honeybee colonies, emphasis from the government and tourist attraction sites, all of which provide a lucrative market opportunity to sell honey at a premium price. To ensure the beekeeping industry thrives in the area and contributes to the growth and development of rural livelihoods, it is crucial to address the challenges faced by beekeepers.
Advancements in Machine Learning-based Predictive Models for Bipolar Disorder Episodes
Authors: N Kumaran , C Aarthy , N Shanmugapriya , B Renuga Devi
Published: December 2024

Diagnosing bipolar disorder presents significant challenges due to the disorder's diverse mood patterns, which complicate the accurate identification of mood fluctuations. However, with systematic evaluation and comprehensive analysis, enhancing diagnostic precision and improving treatment outcomes is feasible. The unclear etiology is influenced by multiple factors, such as changes in brain structure, genetic predispositions, and environmental conditions. The current diagnostic challenges prompt the exploration of machine learning (ML). This study presents a novel computational framework that uses machine learning to help diagnose bipolar disorder, with a focus on mood swing patterns derived from behavioral stimulation. The proposed framework comprises three operational models: a dynamic mood transition model based on stochastic processes, a binary mood state classification model using a Bayesian neural network, with a predictive analysis model powered by Recurrent Neural Decision Trees. Performance comparisons with existing methods demonstrate the proposed framework's enhanced accuracy and reduced processing time, providing a refined approach to feature extraction, classification, and learning optimization for enhanced diagnostic accuracy in bipolar disorder. The proposed approach holds significant promise for enhancing bipolar disorder diagnosis.
A Administração Oral de Nitrito a Curto Prazo Diminui a Rigidez Arterial em Ratos Wistar Treinados e Sedentários
Authors: Souza Thiago Pereira , Tardelli Lidieli Pazin , Nicoletti Rafael Antunes , Jacomini André Mourão , Martins Gabriel Francisco de Mello , Pinheiro Lucas Cézar , Tanus-Santos José Eduardo , Amaral Sandra Lia do , Zago Anderson Saranz
Published: December 2024

Resumo Fundamento O óxido nítrico (NO) desempenha um papel importante na regulação da pressão arterial (PA), atuando diretamente na resistência vascular periférica por meio da vasodilatação. O treinamento físico (via eNOS/NO) e a ingestão de nitrito foram considerados os principais estímulos para o aumento do NO. Objetivo No presente estudo, examinamos os efeitos da administração oral de nitrito e do treinamento com exercícios aeróbicos sobre a PA e rigidez arterial de ratos Wistar. Métodos Trinta e nove (39) ratos Wistar machos jovens foram divididos nos seguintes grupos (n=9 ou 10 por grupo): Sedentário-Controle (SC), Sedentário-Nitrito (SN), Treinado-Controle (TC) e Treinado-Nitrito (TN). Eles foram submetidos a treinamento físico aeróbico em esteiras por 8 semanas (50-60% da capacidade física, 1h/dia, 5 dias/semana) ou mantidos sedentários. Nos últimos 6 dias de treinamento, nitrito foi administrado oralmente (15 mg/Kg por gavagem). A PA, a rigidez arterial e as concentrações plasmáticas e teciduais de nitrito foram avaliadas após o treinamento e o período de administração oral de nitrito. O nível de significância foi definido como p < 0,05. Resultados A administração oral de nitrito foi eficaz na redução dos valores de rigidez arterial (TN, -23%; e SN, -15%). Ambos os grupos que tiveram apenas um tipo de intervenção apresentaram PA sistólica menor em comparação com o controle (TC vs. SC, -14,23; e SN vs. SC, - 12,46). Conclusão Assim, concluímos que a administração oral de curta duração (6 dias), associada a um programa de treinamento físico aeróbico promovem diversos benefícios hemodinâmicos em ratos Wistar machos, como melhorias na rigidez arterial e na PA. Essas respostas sugerem que o treinamento físico e a suplementação de nitrito de sódio podem ser alternativas satisfatórias para a prevenção e tratamento da hipertensão.
Short-term Oral Nitrite Administration Decreases Arterial Stiffness in Both Trained and Sedentary Wistar Rats
Authors: Souza Thiago Pereira , Tardelli Lidieli Pazin , Nicoletti Rafael Antunes , Jacomini André Mourão , Martins Gabriel Francisco de Mello , Pinheiro Lucas Cézar , Tanus-Santos José Eduardo , Amaral Sandra Lia do , Zago Anderson Saranz
Published: December 2024

Abstract Background Nitric Oxide (NO) plays an important role in blood pressure (BP) regulation, acting directly on peripheral vascular resistance through vasodilation. Physical training (via eNOS/NO) and intake of nitrite have been considered major stimuli to increase NO. Objective We examined the effects of oral nitrite administration and aerobic exercise training on BP and arterial stiffness in Wistar rats. Methods Thirty-nine (39) young male Wistar rats were divided into the following groups (n = 9 or 10 per group): Sedentary-Control (SC), Sedentary-Nitrite (SN), Trained-Control (TC), and Trained-Nitrite (TN). They were submitted to aerobic physical training on treadmills for 8 weeks (50-60% of physical capacity, 1h/day, 5 days/week) or kept sedentary. In the last 6 days of training, oral nitrite was administered (15 mg/Kg by gavage). BP, arterial stiffness, and plasma and tissue nitrite concentrations were assessed after the training and oral nitrite administration period. The significant level was defined as p < 0.05. Results Oral administration of nitrite was effective in reducing arterial stiffness values (TN, -23%; and SN, -15%). Both groups that had only one type of intervention showed lower systolic BP compared with control (TC vs. SC, -14.23; and SN vs. SC, - 12.46). Conclusion We conclude that short-term oral administration for 6 days and an aerobic physical training program promote several hemodynamic benefits in male Wistar rats, such as improvements in arterial stiffness and BP. These responses suggest that physical training and sodium nitrite supplementation can be alternatives for the prevention and treatment of hypertension.