bluuebunny/crossref_metadata_2025 huggingface dataset:
Biomarkers of male hypogonadism in childhood and adolescence
Authors: Rey Rodolfo A.
Published: May 2020

Objectives

The objective of this review was to characterize the use of biomarkers of male hypogonadism in childhood and adolescence.

Contents

The hypothalamic-pituitary-gonadal (HPG) axis is active during fetal life and over the first months of postnatal life. The pituitary gland secretes follicle stimulating hormone (FSH) and luteinizing hormone (LH), whereas the testes induce Leydig cells to produce testosterone and insulin-like factor 3 (INSL), and drive Sertoli cells to secrete anti-Müllerian hormone (AMH) and inhibin B. During childhood, serum levels of gonadotropins, testosterone and insulin-like 3 (INSL3) decline to undetectable levels, whereas levels of AMH and inhibin B remain high. During puberty, the production of gonadotropins, testosterone, and INSL3 is reactivated, inhibin B increases, and AMH decreases as a sign of Sertoli cell maturation.

Summary and outlook

Based on our knowledge of the developmental physiology of the HPG axis, these biomarkers can be used in clinical practice to interpret the physiopathology of hypogonadism. Additionally, these markers can have diagnostic value in different forms of hypogonadism that may appear during childhood and adolescence.
Broad spectral lines in AGNs and supermassive black hole mass measurements
Authors: Popović Luka Č.
Published: May 2020

The mass measurement of supermassive black holes (SMBHs) is a very complex task. Between several methods for SMBH mass measurements, some of them use the spectral lines, which indicate the motion of the emitting/absorbing material around an SMBH. Mostly, there is an assumption of virialization of line emitting gas in the region which is close to the central SMBH. In this paper we will give an overview of methods for the SMBH mass measurements using broad emission spectral lines observed in Type 1 AGNs. First we give the basic idea to use the parameters of broad lines to SMBH mass measurements. After that we give an overview of broad lines from X-ray (Fe kα) to the IR (Pashen and Brecket lines) which have been used for SMBH mass estimates. Additionally, we describe and discuss a new method for SMBH mass measurements using the polarization in the broad lines emitted from Type 1 AGNs.
Nonlinear flexural analysis of sandwich beam with multi walled carbon nanotube reinforced composite sheet under thermo-mechanical loading
Authors: Lal Achchhe , Markad Kanif
Published: May 2020

Nonlinear flexural analysis of sandwich composite beam with multiwall carbon nanotube (MWCNT) reinforced composite face sheet and bottom sheet under the thermo-mechanically induced loading using finite element method is carried out. Solution of current bending analysis is performed using Newton’s Raphson approach by using higher order shear deformation theory (HSDT) and non-linearity with Von Kármán kinematics. The sandwich laminated composite beam is subjected to uniform, linear and nonlinear varying temperature distribution through thickness of the beam. The sandwich beam with MWCNT reinforced composite facesheet and bottom sheet is subjected to point, uniformly distributed (UDL), hydrostatic and sinusoidal loading. The two phase matrix is utilized with E-Glass fiber to form three phase composite face sheet and bottom sheet by Halpin-Tsai model. The static bending analysis is performed for evaluating the transverse central deflection of three and five layered sandwich composite beam. Transverse central deflection is measured by varying CNT volume fraction, uniformly distributed, linearly and nonlinear varying temperature distribution, thickness ratio, boundary condition, number of walls of carbon nanotube by using interactive MATLAB code.
Nouveau fragment arabe du De aeternitate mundi contra Aristotelem de Jean Philopon
Authors: Rashed Marwan
Published: May 2020

This paper presents a new fragment of Philoponus' treatise De aeternitate mundi contra Aristotelem. The fragment, preserved only in an Arabic translation by al-Bīrūnī, derives in all probability from the third book of the treatise, and it deals with the moonstone or selenite. It is hypothesized that this mirabile, which is described by Damascius in his Life of Isidore, was deployed by Philoponus at the point of his polemic against Aristotle.
Pyrrhonism, Inquiry, and Rationality
Authors: Machuca Diego E.
Published: May 2020

In this paper, I critically engage with Casey Perin's interpretation of Sextan Pyrrhonism in his recent book, The Demands of Reason: An Essay on Pyrrhonian Scepticism. From an approach that is both exegetical and systematic, I explore a number of issues concerning the Pyrrhonist's inquiry into truth, his alleged commitment to the canons of rationality, and his response to the apraxia objection.
L'interpretazione del Teeteto e la natura della epistemologia platonica. Alcune osservazioni
Authors: Ferrari Franco
Published: May 2020

This article replies to the critical note by Trabattoni («Elenchos», xxxiii (2012) pp. 69-107). The author defends his interpretation of Plato's Theaetetus against Trabattoni's objections, arguing that the maieutic and peirastic character of the dialogue explains its negative or aporetic conclusion. For the failure of all the attempts to define knowledge in the dialogue doesn't mean that, according to Plato, knowledge is not possible for men or that it can be identified with doxa; on the contrary, Plato clearly states that the philosopher, i.e. the dialectician, is absolutely able to attain the perfect knowledge of the forms. The subsequent failures in the Theaetetus, particularly the last two, depend on the admission of an "additive model'' according to which knowledge is "doxa plus something'', an epistemological attitude that is explicitly rejected in the Meno.
Stasis del alma y psicologización de la política en República IV
Authors: Soares Lucas
Published: May 2020

In Republic 436a-c Plato introduces, for the first time, the problematic postulate of the tripartition of the species-functions of the soul to pass on to justify it by starting from the so-called “Principle of conflict” or “of the impossibility of opposites”. To reach this point in the dialogue, we will firstly place this passage in the conceptual architecture of the work, taking the topic of stasis (sedition, revolt, civil war) as the thread for the reconstruction of the argumentative sequence that leads into the psychological model of the parts in conflict. We actually start from the hypothesis that Plato gets to the tripartition of the soul from the evidence that in the psychological reality of the individual there exists a stasis that is produced in the soul due to injustice, contrasting to the concord and friendship that is a result of justice. On the basis of the psychological model of the parts in conflict, the psycho-political objective looked for in Republic, points to the achievement of the psychic unity as a condition for the political unity; since Plato’s political objective is to make citizens become better, which can only be reached through an improvement of the individual soul. Through the topic of stasis and the lexis of the conflict that derives from it, we uphold that Plato intends to prove not only the political and tripartite constitution of the soul, but first and foremost the priority that the psychic tripartition holds over the political order.
Knowing by Doing: The Role of Geometrical Practice in Aristotle’s Theory of Knowledge
Authors: Ugaglia Monica
Published: May 2020

Aristotle’s way of conceiving the relationship between mathematics and other branches of scientific knowledge is completely different from the way a contemporary scientist conceives it. This is one of the causes of the fact that we look at the mathematical passages we find in Aristotle’s works with the wrong expectation. We expect to find more or less stringent proofs, while for the most part Aristotle employs mere analogies. Indeed, this is the primary function of mathematics when employed in a philosophical context: not a demonstrative tool, but a purely analogical model. In the case of the geometrical examples discussed in this paper, the diagrams are not conceived as part of a formalized proof, but as a work in progress. Aristotle is not interested in the final diagram but in the construction viewed in its process of development; namely in the figure a geometer draws, and gradually modifies, when he tries to solve a problem. The way in which the geometer makes use of the elements of his diagram, and the relation between these elements and his inner state of knowledge is the real feature which interests Aristotle. His goal is to use analogy in order to give the reader an idea of the states of mind involved in a more general process of knowing.
Pyrrhonian Relativism
Authors: Machuca Diego
Published: May 2020

This paper argues that Sextus Empiricus’s Pyrrhonism is a form of relativism markedly different from the positions typically referred to by this term. The scholars who have explored the relativistic elements found in Sextus’s texts have claimed that his outlook is not actually a form of relativism, or that those elements are inconsistent with his account of Pyrrhonism, or that he is confusing skepticism with relativism. The reason for these views is twofold: first, when employing the term “relativism” one hardly has in mind the sort of relativistic stance adopted by the Pyrrhonist; and second, those scholars have misinterpreted Sextus’s relativistic remarks. The purpose of this paper is to show that he adopts a phenomenological kind of relativism that is compatible with his account of Pyrrhonism.
Il confronto di Giovanni Filopono con Alessandro di Afrodisia intorno al problema della conversione delle proposizioni
Authors: Gili Luca
Published: May 2020

In this paper I compare Philoponus’s account of the laws of conversion for categorical and modal propositions with Alexander’s exposition of the same topic. I argue that Philoponus’s main source was Alexander’s commentary on Aristotle’s Prior Analytics and that Philoponus had no access to independent sources to reconstruct Theophrastus’s proof for the conversion of universal negative propositions. I suggest that the different solutions that Alexander and Philoponus offer to the puzzles of the doctrine of the laws of conversion depend on the two commentators’ different exegetical strategies. Alexander tries to solve the puzzles by means of doctrines, which Aristotle expounded elsewhere. Philoponus instead interprets Aristotle’s passage as implying a hierarchy among propositions - a doctrine which is not explicitly present in Aristotle’s text.
Bergson lettore del misticismo plotiniano. Note autografe inedite
Authors: Taormina Daniela Patrizia
Published: May 2020

Bergson interprets Plotinian mysticism in the light of his distinction between two different kinds of mysticism: one which translates union with God into action, the other which translates it into contemplation. Plotinus embodies the highest expression of the latter, intellectual mysticism. This thesis runs through Bergson’s oeuvre from his early works to Les Deux Sources de la morale et de la religion. The present study traces its origins back to a reading of Ennead VI 9 on the basis of notes in the philosopher’s own hand, in all likelihood pertaining to the lecture course he delivered at the Collège de Fance in 1901-1902. These notes, here published for the first time, show that a careful engagement with the Plotinian text led Bergson to stress the continuity between two forms of ecstasy, regarded as stages in the soul’s return to its source: in the first stage, the soul reverts to the intelligible and identifies with it (intellectual ecstasy); in the second, the intellect, united with itself, attains ultimate unity (supra-intellectual ecstasy). In both cases, the soul does not identify with God’s creative will and hence the ecstasy it experiences is still a theoretical, or intellectual, one.
Le vers 4 du fragment 115 d’Empédocle (FVS 31 D.-K.): proposition d’une correction
Authors: Meulder Marcel
Published: May 2020

By establishing a link between Homer’s, Hesiod’s and Empedocles’ similar textual expressions, we are allotted to assert that the fourth line of Empedocles’ fragment 115 (FVS 31) is authentic. We must read the first words of this line so: ὅς κεν ἑκὼν ἐπίορκον… This emendation of Empedocles’ text implies that the guilty god (or man or Blessed) whom Empedocles’ fragment mentions, is not urged by an (positive or negative) outside element, nor is deceived by a god or a man, acts quite willingly and like the Hatred to which he adheres, and behaves like an human being. However he differs from the disloyal man; for, once punished and cleansed, he is allotted to go back to the society of the Gods or the Blessed, whereas the disloyal man becomes blind or dies, as the myth of the Sicilian Palici testifies. Empedocles refers to this myth when he is speaking over the goddess Nestis.
Aristotle’s Way away from Parmenides’ Way. A Case of Scientific Controversy and Ancient Humour
Authors: Quarantotto Diana
Published: May 2020

In Physics Α, Aristotle introduces his science of nature and devotes a substantial part of the investigation to refuting the Eleatics’ theses, and to resolving their arguments, against plurality and change. In so doing, Aristotle also dusts off Parmenides’ metaphor of the routes of inquiry and uses it as one of the main schemes of his book. Aristotle’s goal, I argue, is to present his own physical investigation as the only correct route, and to show that Parmenides’ “way of truth” is instead both wrong and a sidetrack. By revisiting Parmenides’ metaphor of the route, Aristotle twists it against him, distorts it and uses this distortion as a source of fun and of some mockery of Parmenides himself. Thereby, Physics Α gives us a taste of Aristotle’s biting humour and of his practice of the “virtue” of wit (eutrapelia).
Programming and control for skill-based robots
Authors: Saukkoriipi Janne , Heikkilä Tapio , Ahola Jari M. , Seppälä Tuomas , Isto Pekka
Published: May 2020

This paper considers programming and control of skill-based robots. Robot skills are used to integrate and synchronize robot actions and sensor data in a consistent way. Skill-based approach provides a framework for configurable robot systems, enabling quick setups and start-ups of applications. In the paper we will introduce skill programming and skill control concepts in more detail and how they relate to usage of models and sensors. We will also give a practical example for programming and implementing skills for a grinding application.
Using Digital Twin Technology in Engineering Education – Course Concept to Explore Benefits and Barriers
Authors: Liljaniemi Antti , Paavilainen Heikki
Published: May 2020

Digital Twin (DT) technology is an essential technology related to the Industry 4.0. In engineering education, it is important that the curricula are kept up-to-date. By adopting new digital technologies, such as DT, we can provide new knowledge for students, teachers, and companies. The main aim of this research was to create a course concept to research benefits and barriers of DT technology in engineering education. The research confirmed earlier findings concerning digitalization in engineering education. DT technology can increase motivation for studying and improve learning when applied correctly.
A Slow Unfolding “Fault Sequence”: Risk and Responsibility in Lucy Kirkwood’s The Children
Authors: Hoydis Julia
Published: May 2020

British playwright Lucy Kirkwood’s The Children (2016) tackles the imaginative challenge of depicting environmental crisis, in particular the risks of nuclear destruction and climate change. With questions of intra- and intergenerational justice being at the heart of the dramatic text, this article draws on conceptions and insights from cultural risk theory to argue that human risk behaviour and decision-making is the play’s main focus and determines characterisation as well as structure. Interrogating the tension between aesthetic form and content, it shows how The Children naturalizes the (post-)apocalyptic condition and strives for a balance of scales with regard to collective and personal crisis. Characteristic of the rapidly growing corpus of contemporary “cli-fi” drama, and in accordance with many of the strategies proclaimed by climate communication theory, the play stages the catastrophic implications of environmental destruction predominantly as collective risk management and in a predominantly realist manner, discarding formal experimentation as well as futurist setting. Yet this article argues that it remains ambiguous what kind of risk management is proposed and whether we should read it as a call for action or as an imaginative means of accepting finitude.
Organic electrochromic molecules: synthesis, properties, applications and impact
Authors: Stolar Monika
Published: May 2020

Organic electronics are at the forefront of modern research, with goals of creating more efficient and environmentally benign devices. Organic molecules can achieve this as they typically result in materials that are solution-processable and less toxic than their transition-metal counterparts. Electrochromic molecules have unique color changing properties upon passing an electrical current making them highly sought after for colored displays, dimming mirrors, and smart windows. Part of my PhD work was devoted to developing a new class of electrochromic molecules, the phosphoryl-bridged viologens, with more favorable redox properties and new color changing modes. In order to understand the necessity and potential of new electrochromes, it is important to assess the history of the field and its future. In addition to designing new molecules for electrochromic devices, it is equally important to design a multifunctional species with a bright, competitive future across various organic electronic applications.
Removal of chromium ions by functional polymers in conjunction with ultrafiltration membranes
Authors: Sánchez Julio , Rodriguez Carol , Oyarce Estefanía , Rivas Bernabé L.
Published: May 2020

In the current research water-soluble functional polymers (WSFP) were prepared via radical polymerization and purified by fractionation through ultrafiltration membranes with different molecular weights cut off (MWCO) of 30 and 100 kDa. The WSFPs were poly(3-acrylamide propyl) trimethyl ammonium chloride, P(ClAPTA), poly(2-acrylamido-2-methyl-1-propane sodium sulfonate, P(AMPSNa), and poly(3-methacrylamino propyl) dimethyl 3-sulfopropyl ammonium hydroxide, P(HMPDSPA). These polymers were characterized by Fourier transformed infrared spectroscopy (FT-IR) and thermogravimetry analysis (TGA). Using liquid-phase polymer-based retention technique (LPR), chromium [Cr(III) and Cr(VI)] retention was studied as a function of pH, polymer and chromium concentration, selectivity, maximum retention capacity, chromium elution capacity, and polymer regeneration through sorption and desorption studies. Results of FT-IR showed the characteristic absorption bands of the synthesized polymers. The decomposition temperatures of P(ClAPTA) were at 303.1 °C, and for P(AMPSNa) three decompositions temperatures were registered at 190.5 °C, 223.2 °C, and 304.8 °C. P(HMPDSPA) presented two important decomposition temperatures at 292.4 °C and 391.7 °C, respectively. Concerning to the retention of Cr(VI), it was maximal (100 %) when P(ClAPTA) was studied at pH 6. The maximum retention of Cr(III) (100 %) was achieved by P(AMPSNa) at pH 3. The optimum polymer:Cr mole ratio obtained was 10:1 for both Cr(VI) and Cr(III). The retention of Cr(VI) decreased due to the presence of interfering ions, and the hydrodynamic flow was almost constant during the ultrafiltration of polymer-Cr macromolecule.
Making out with the world and valuing relationships with humans
Authors: Liberati Nicola
Published: May 2020

This paper aims to analyze the effects of the introduction of teledildos on our sexual lives according to postphenomenology and mediation theory. Digital technologies are getting very intimate by mediating even our sexual intercourse, as in the case of teledildonics. According to postphenomenology and mediation theory, technologies are never neutral, but they change how we live and how we relate to the world around us. Thus, we need to ask how these intimate technologies are going to affect us in the way we live our intimacy and relationships. This paper will show how teledildonics will allow human beings to have sexual intercourse with every object around by turning them into sexually interactive "quasi-others", and how this change will affect the way we give meanings and values to love and sex in general. The first part of this paper will show the introduction of teledildonics will affect how we perceive the world around us and how we are tempted by it. The second part will highlight how even the meanings and values we give to sex and love will be shaped according to the new potentialities provided by teledildos.
The moral case for sexbots
Authors: Behrendt Marc
Published: May 2020

In this paper, I will try to examine the main objections and moral qualms by some opponents to sexbots. While minor points of their argumentation are not entirely groundless, my aim is to show that overall, most of the claims directed against sexbots are: (1) rarely based on facts or data; (2) driven by unfounded fears; and originate from; (3) implicit to very strong political and ideological beliefs.

The driving moral forces behind the opponents’ position are not traditional moral categories such as good or bad per se, but they are rather subsumed or dissolved under very vague and fashionable concepts such as gender and objectification. Hence, morality in this case can be seen as highly subservient to a political cause: it views some aspects of technological progress as an offshoot of all-mighty capitalism; and sexbots in particular, as a threat to social order, that will redefine or even wipe out traditional interactions between human beings and ultimately, destroy humanity.

I will argue on the contrary that there is a strong moral case for sexbots, that stems from notions such as sexual liberty, personal freedom and humanism, and extends to novel concepts, like sexual equality or sexual opportunity, sexual justice and compassion.

Moreover, I am fairly convinced that sexbots, widely available and used in a responsible manner, might have a positive impact on society as a whole. The sexual well-being and fulfilment of individuals in want of intimacy and emotional connection, could be seen as a tool for social progress and sexual justice.

As Socrates brilliantly pointed out through Plato, most of human misery, suffering and wars, arise from our unfulfilled bodily desires and frustrations (“Phaedo”, 66c). He of course advocated in favour of chastity and resisting sexual temptation, but his basic premise and insight are still valid today.

Finally, the underlying questions I will explore in the following pages are: how come such vast swaths of the progressive camp, adopt a conservative discourse, when it comes to sexual progress? Why is there such a staunch opposition to sexbots and the ensuing right to pleasure, while at the same time, we are precisely witnessing in the most recent decades, an inflation in all kinds of subjective rights, that we tend to value so much?
Evaluating Visualisations in Voting Advice Applications
Authors: Bruinsma Bastiaan
Published: May 2020

While the design of voting advice applications (VAAs) is witnessing an increasing amount of attention, one aspect has until now been overlooked: its visualisations. This is remarkable, as it are those visualisations that communicate to the user the advice of the VAA. Therefore, this article aims to provide a first look at which visualisations VAAs adopt, why they adopt them, and how users comprehend them. For this, I will look at how design choices, specifically those on matching, influence the type of visualisation VAAs not only do but also have to, use. Second, I will report the results of a small-scale experiment that looked if all users comprehend similar visualisations in the same way. Here, I find that this is often not the case and that the interpretations of the users often differ. These first results suggest that VAA visualisations are wrongly underappreciated and demand closer attention of VAA designers.
KAWASAN WISATA PENDIDIKAN LINGKUNGAN HIDUP (KWPLH) BALIKPAPAN SEBAGAI SUMBER BELAJAR KONSERVASI
Authors: Ngabekti S.
Published: May 2020

Penelitian ini bertujuan untuk mengkaji Kawasan Wisata Pendidikan Lingkungan Hidup (KWPLH) Balikpapan sebagai sumber belajar konservasi. Metode penelitian adalah metode survai instansional dan pengamatan lapangan. Berdasarkan hasil pengamatan lapangan, pengelolan enklosur beruang madu seperti di habitat alami, dan aktivitasnya dapat diamati oleh masyarakat sebagai sumber belajar konservasi. Analisis dokumen buku tamu (2012) menunjukkan KWPLH Balikpapan dikunjungi oleh 50.000 70.000 orang. Pendapat pengunjung secara ringkas dapat disimpulkan bahwa KWPLH Balikpapan merupakan tempat yang nyaman untuk belajar dan berpotensi bagus untuk memperoleh pengetahuan, dan upaya pelestarian beruang madu beserta habitatnya.This study aims to assess Kawasan Wisata Pendidikan Lingkungan Hidup (KWPLH) Balikpapan as a learning resource of conservation. The research method is institutional survey and field observation. Based on field observations, such as the management of bears enclosure in their natural habitat, and its activity can be observed by the community as a learning resource of conservation. Analysis of guest book documents (2012) indicated that KWPLH Balikpapan visited by 50,000-70,000 people. Opinions from visitors briefly can be concluded that KWPLH Balikpapan is a comfortable place to learn and have a good potential to acquire knowledge, and the effort to conserve sun bears and their habitat.
ELEMEN BERNALAR TUJUAN PADA PEMBELAJARAN IPA MELALUI PENDEKATAN METAKOGNITIF SISWA SMP
Authors: Patonah S.
Published: May 2020

Tujuan dari penelitian ini adalah untuk mengembangkan pembelajaran IPA menggunakan pendekatan metakognitif untuk meningkatkan kemampuan berfikir kritis pada siswa. Metode penelitian yang digunakan adalah triangulasi mix method design. Dari hasil pengamatan, sejumlah 6 kelompok telah merespon pertanyaan, sehingga semua dapat dikatakan telah berpikir kritis karena dapat menginterpretasikan hasil pengamatan pada video dan dapat mempertimbangkan hasil percobaan sebelumnya. Penerapan pembelajaran IPA dengan pendekatan metakognitif dapat membuat siswa berpikir tentang perencanaan kerja sampai dengan pemecahan masalah yang dihadapiThe purpose of this study is to develop a learning science using metacognitive approach to enhance the ability of critical thinking in students . The research method used is triangulation mixed method design. From the results, a number of 6 groups have responded to the question , so that all can be said to have critical thinking because it can interpret the results of observations on video and can consider the results of previous experiments. The application of science learning with metacognitive approach can make students think about the planning work to solving those problems.
PERANGKAT PEMBELAJARAN PROBLEM BASED LEARNING BERORIENTASI GREEN CHEMISTRY MATERI HIDROLISIS GARAM UNTUK MENGEMBANGKAN SOFT SKILL KONSERVASI SISWA
Authors: Rosita A. , - Sudarmin , Marwoto P.
Published: May 2020

Penelitian ini bertujuan untuk mengembangkan perangkat pembelajaran problem based learning berorientasi green chemistry pada materi hidrolisis garam untuk mengembangkan soft skill konservasi siswa SMA. Metode penelitian ini adalah research and development (R&D). Hasil penelitian menunjukkan LKS yang dikembangkan sangat layak untuk digunakan dalam pembelajaran kimia. Perangkat pembelajaran dapat meningkatkan pemahaman konsep siswa materi hidrolisis garam dengan N-gain sebesar 0,63 (sedang). Peningkatan soft skill konservasi siswa yang berkriteria tinggi sebanyak 35,48 % sedangkan yang berkriteria sedang 64,52 %.This research has aim to developt teaching and learning instrument application on problem based learning which oriented on green chemistry on salt hydrolisys for developing conservation soft skill for student. The method of this research is research and development (R&D). The results showed a very worthy worksheets developed for use in teaching chemistry. Teaching instrument can improve the understanding of student concept of salt hydrolysis matery can get N-gain 0,63 (medium). The improving soft skill of student conservation has high criteria 35,48%. For medium has 64,52%.
Estimating the Hurst index of the solution of a stochastic integral equation
Authors: Kubilius Kęstutis , Melichov Dmitrij
Published: May 2020

Let X(t) be a solution of a stochastic integral equation driven by fractional Brownian motion BH and let V2n (X, 2) = \sumn-1 k=1(\delta k2X)2 be the second order quadratic variation, where \delta k2X = X (k+1/N) − 2X (k/ n) +X (k−1/n). Conditions under which n2H−1Vn2(X, 2) converges almost surely as n → ∞ was obtained. This fact is used to get a strongly consistent estimator of the Hurst index H, 1/2 < H < 1. Also we show that this estimator retains its properties if we replace Vn2(X, 2) with Vn2(Y, 2), where Y (t) is the Milstein approximation of X(t).
Differential geometry of intersection curve of two surfaces
Authors: Navickis Kazimieras
Published: May 2020

In this this article the differential geometry of intersection curve of two surfaces in the three dimensional euclidean space is considered.In case, curvature and torsion formulas for such curve are defined.
Analysis of teaching programming basics from pupils’ viewpoint
Authors: Blonskis Jonas , Burbaitė Renata , Dagienė Valentina
Published: May 2020

Teaching programming in a comprehensive school is a long and difficult process, which is why it should be analysed from various points of views. An analysis of pupils’ opinion on the lesson of programming basics has been carried out by combining pedagogical observation method with continuing questionnaires of pupils. Having processed the data of analysis, it has been determined that pupils’ cooperation with teacher and friends has a considerable influence on the success of learning programming. Moreover, the analysis has revealed that not only the final result is important but also the process of learning. In this article, the most common difficulties that pupils encounter when learning programming are discussed and their reasons are indicated. Having processed the results of pupils’ test task solutions, an attempt was made to determine if the pupils evaluate their knowledge, abilities and skills objectively. Finally, recommendations to teachers are given on the grounds of the results of the analysis.
European student’s mathematical olympiad’ 09
Authors: Dzindzalieta Dainius
Published: May 2020

In this article we talk about Vojtech Jarn¸ kk International Mathematical Competition for students’ also called “Europe’09 student olympiad” which was held in Czech Republic, Ostrava. We also give some problems and one solution of not the hardest problem.
Numerical simulation of the influence of the fluctuations of the biosensor’s parameters on its response
Authors: Štikonienė Olga , Ivanauskas Feliksas
Published: May 2020

The mathematical model of the electrochemical glucose biosensor based on the enzymatic conversionof the substrate and the diffusion of the substrate was used. The influence of the fluctuations of themembrane thickness, the diffusion coefficients and pH were modelled and their impact was evaluated atdifferent modes of an action of the biosensor.
Possibilities of improving the learning quality of mathematics in Kaunas University of Technology
Authors: Novikienė Regina , Matiukaitė Rasa
Published: May 2020

The learning quality of mathematics is perceived in the article from educational perspective as the existence of arranged educational system that allows implementing the aims of the course taught. The article reveals the possibilities of improving the quality while teaching first year students of Kaunas University of Technology. The conclusions are based on student test results, the analysis of scientific literature and practical experience of the authors.
Trigonometric functions in the secondary school
Authors: Vaškas Petras
Published: May 2020

In the school mathematics trigonometric functions for acute angle and obtuse angle are defined differently. The common definitions of trigonometric functions for the both cases in the paper are proposed.
Petras Vileišis (1851–1926) as the Pioneer in creating Lithuanian “Arithmetic”
Authors: Banionis Juozas
Published: May 2020

Petras Vileišis (1851–1926) is one of the most prominent Lithuanian personalities at the end of the 19th c. and the beginning of the 20th c., who was distinguished for his universal activity. He is mostly well known as an engineer, a man in culture, a public man, a promoter of Lithuanianism. However, Petras Vileišis’s merit in the development of Lithuanian mathematical education is underestimated. The article throws the light on the circumstances of creating “Arithmetic” by a diplomaed mathematician P. Nėrys (P. Vileišis), its content and the importance for mathematical education in Lithuania.
Computational modeling of the kinetics of lipase catalyzed reaction
Authors: Dabulyt-Bagdonavičienė Jurgita , Ivanauskas Feliksas , Razumas Valdemaras
Published: May 2020

The kinetics of lipase catalyzed reaction (hydrolysisof ascorbic acid palmitate), described by the system of simple non-linear differential equations was presented. The system was solved analytically and the result expressed by formula. With reference to calculated solution the current dependence on various parameters was performed. The comparison of experiments [3] and calculated results was made.
Asymmetric cipher protocol using conjugacy and discrete logarithm problem
Authors: Raulynaitis Andrius , Venclovienė Agnė
Published: May 2020

The paper proposes asymmetric cipher protocol based on matrix field over some field F. The asymmetric cipher is based on two simultaneous problems: matrix conjugator search problem (MCSP) and matrix discrete logarithm problem (MDLP). The algorithm construction does not allow performing a crypto-analysis by replacing the existing MCSP solution to the matrix decomposition problem (MDP) solution. The security parameters are defined and preliminary security analysis is presented.
Analysis of pricing models for options
Authors: Landauskas Mantas , Valakevičius Eimutis
Published: May 2020

The program developed was effective in time of calculation and let us state, that binomial and Markovian models give similar results, but Markovian model is much slower when lattice has more than 25 periods. The crude Monte Carlo Model requires millions of paths to be generated in order to get high accuracy.
Computation of Nash equilibria in three-personmatrix game
Authors: Vakarinienė Sigutė , Sudžiūtė Daina
Published: May 2020

The method for finding Nash equilibrium in three-person matrix game is introduced in this paper. Linear optimization model with binary variables for computation of equilibrium points in three-person matrix game is proposed.
Application of the MUSIC method for estimation of the signal fundamental frequency
Authors: Šimonytė Virginija , Pyž Gražina , Slivinskas Vytautas
Published: May 2020

The goal of the paper is to use the MUSIC method to estimate the fundamental frequency of signals, and compare the results with the ones obtained by the DFT method. Real speech signals are considered in the paper. Lithuanian vowel sound fundamental frequency is estimated by the MUSIC and DFT methods.
Geometric max stability of random vectors
Authors: Aksomaitis Algimantas , Ivanovienė Irma
Published: May 2020

Geometric max (min) stability of random variables is investigated enough. In this article, geometric stability concept is extended for the vectors. We also search connections between the geometric max (min) stability and max (min) stability of vectors.
Would You Prescribe Mobile Health Apps for Heart Failure Self-care? An Integrated Review of Commercially Available Mobile Technology for Heart Failure Patients
Authors: Mortara Andrea , Vaira Lucia , Palmieri Vittorio , Iacoviello Massimo , Battistoni Ilaria , Iacovoni Attilio , Macera Francesca , Pasqualucci Daniele , Bochicchio Mario , De Maria Renata
Published: May 2020

Treatment of chronic diseases, such as heart failure, requires complex protocols based on early diagnosis; self-monitoring of symptoms, vital signs and physical activity; regular medication intake; and education of patients and caregivers about relevant aspects of the disease. Smartphones and mobile health applications could be very helpful in improving the efficacy of such protocols, but several barriers make it difficult to fully exploit their technological potential and produce clear clinical evidence of their effectiveness. App suppliers do not help users distinguish between useless/dangerous apps and valid solutions. The latter are few and often characterised by rapid obsolescence, lack of interactivity and lack of authoritative information. Systematic reviews can help physicians and researchers find and assess the ‘best candidate solutions’ in a repeatable manner and pave the way for well-grounded and fruitful discussion on their clinical effectiveness. To this purpose, the authors assess 10 apps for heart failure self-care using the Intercontinental Marketing Statistics score and other criteria, discuss the clinical effectiveness of existing solutions and identify barriers to their use in practice and drivers for change.
Leishmaniose visceral humana: um retrato da situação de casos em idosos e longevos
Authors: Mahmud Ibrahim Clós , Kowalski Carla Viero , Behar Paulo Renato Petersen , Stobäus Claus Dieter
Published: May 2020

Aims: to analyze the current Brazilian and of the state of Rio Grande do Sul epidemiological situation of visceral leishmaniasis (LVH) in the elderly and verifythe mortality coefficient.Methods: This is a cross-sectional study with a secondary data source, taken from SINAN data from January 2013 to December 2017, with confirmed visceral leishmaniasis in Brazil and Rio Grande do Sul, which are tabulated in Excel and analyzed with Epiinfo 7.Results: cases of LVH in the elderly have increased in the last 5 years, within the Brazilian and the state of Rio Grande do Sul settings. Although not widely reported, it is frequent to compromise and increase the proportion of elderly people who die from LVH, which was 20,3% of the cases in the period from 2013 to 2017, demonstrating the seriousness of the infection in this public. In our study we also found a strong relation between age and the increase in the lethality coefficient, reaching 46.87% in 2016.Discussion: One of the recent strategies in the fight against HVL is the slaughter of dogs that contains the parasite responsible for the transmission of the disease, but this method of control has not been very effective. Thus, the immunoprophylactic measurement by Leish-Tec® vaccine has a favorable effect in the fight  against the disease only in animals that are not in high transmission areas.
Desenvolvimento e Validação do Questionário de Conhecimento em Asma Pediátrica (Q-CAP) para população brasileira
Authors: Cardoso Thiago De Araujo , Ribeiro Mariele Cunha , Roncada Cristian , Dos Santos Rejane Rosaria Grecco , Pitrez Paulo Márcio Condessa
Published: May 2020

AIMS: To develop and validate the Knowledge Questionnaire in Pediatric Asthma, in the brazilian Portuguese language.METHODS: The questionnaire was developed based on recognized international instruments. Experts have examined the instrument, along with parents of children with asthma. The tests of construct validity and contents, Cronbach’s alpha, intraclass correlation coefficient, Pearson Correlation, analysis of Kappa and ROC curve.RESULTS: Participated in this study 132 parents of children with asthma, and 117 (88.6%) female, average age of 35.9 ± 9.1 years, 78 (59.1%) with full high school, 73 (59.8%) in the economy class C. The final version of the instrument possessing 20 questions, with cut-off of ≥ 14 points. The total scores obtained “A” concept validity tests/construct and value of 0.69 on Cronbach’s alpha. In the evaluation of correlation intraclass coefficient the questionnaire has within the acceptable  levels (ICC = 0.69; 95% CI = 0.61 ~ 0.77; p < 0.001). The sensitivity and specificity have lodged area of 0.93 (95% CI: 0.84 ~ 1.0; p = 0.002) and values of 80% and 97.1%, respectively. After applying the final version of the questionnaire of knowledge in Pediatric Asthma, only 5 (3.8%) the parents showed  satisfactory levels of knowledge in asthma.CONCLUSION: The Knowledge questionnaire in Pediatric Asthma has proven to be reliable, clear and with suitable levels of reproducibility and internal consistency. Your application is easy and covers the cultural aspects, as well as Brazilian great accuracy in measuring the level of knowledge about asthma.
Articulações sobre ética e inclusão a partir do contexto de uma Escola de Governo
Authors: Dos Santos Mônica Pereira , De Lima Carolina Barreiros , De Oliveira Renato José
Published: May 2020

O presente artigo tem por objetivo compreender os sentidos atribuídos ao termo “ética” durante o processo de desenvolvimento do Index para a Inclusão (BOOTH E AINSCOW, 2011) em uma Escola de Governo, instituição pública que promove a formação e o aperfeiçoamento de agentes públicos. Para tanto, foram analisados dados coletados durante a pesquisa “Desenvolvendo e adaptando o Index para a Inclusão em uma Escola de Governo no Brasil”, que teve por objetivo promover um processo de autorreflexão dentro da Escola e, a partir disso, propor ações que pudessem provocar transformações referentes ao desenvolvimento de culturas, políticas e práticas de inclusão institucionais. Os dados foram analisados a partir da perspectiva Omnilética (SANTOS, 2013) e da Teoria da Argumentação (PERELMAN e OLBRECHTS-TYTECA, 2005). Os resultados apontaram que os sentidos atribuídos ao termo perpassaram pelas ideias de ética como um valor “copiado”; ética e inclusão: sinônimos ou à parte? e ética e sua relação com transparência.
“I felt alone”: The Importance of Social Support for Early Intervention
Authors: Espe- Sherwindt Marilyn , Serrano Ana Maria
Published: May 2020

When adopting an ecological perspective of Early Intervention (EI), social support became a key concept for understanding families and ways of coping with a child who is at-risk or have been diagnosed with Special Educational Needs. Research findings demonstrate that social support, personal well-being, parenting interactional styles, and child development are both conceptually and empirically related, and that variation in child development is attributable to social support and well-being more so than to family Social Economic Status. Social supports play an essential role when planning intervention with young children and their families. This article will provide an evidence based review of the concept and its importance in Early Intervention and it will present a case study to illustrate and operationalize the ideas discussed in the article.***“Eu senti-me só”: a importância do apoio social para a intervenção Precoce***Adotando uma perspetiva ecológica de Intervenção Precoce (IP), o apoio social tornou-se um conceito-chave para entender as famílias e formas de lidar com uma criança em risco ou com Necessidades Educacionais Especiais. Os resultados da investigação demonstram que o apoio social, o bem-estar pessoal, os estilos de interação dos pais e o desenvolvimento infantil estão conceitualmente e empiricamente relacionados, e que as mudanças no desenvolvimento infantil se atribuem mais ao apoio social e ao bem-estar, da família do que ao seu estatuto sócio económico. Os apoios sociais desempenham um papel essencial no planeamento da intervenção com crianças pequenas e suas famílias. Este artigo fornecerá uma revisão baseada em evidências do conceito e sua importância na IP e apresentará um estudo de caso para ilustrar e operacionalizar as ideias discutidas no artigo.Palavras-Chave: Intervenção Precoce, Apoio Social, Apoio Formal e Informal, Ecomapa
Can you hear me? - Accessing the voice of the child with Autism and their parent
Authors: Twomey Miriam
Published: May 2020

The aim of this paper is to access the voices of children with Autism Spectrum Disorders and their parents. This paper engages with philosophical conceptual frameworks exploring concepts of movement and engagement in eliciting child and parent voice. Qualitative, longitudinal case studies were conducted. Semi-structured interviews [n=83] were conducted with stakeholders including parents. Children with and without the label of Autism engaged in interventions drawing on the Creative Arts. Living autoethnography was considered a methodological tenet, establishing connectivity between life and research, self and others, providing a window through which the internal world of the parent was interpreted and understood. This research enabled children and parents to explore their worlds and deliberate on areas that affected their lives. The potential value for using the Creative Arts as a means of engaging children with Autism is discussed. Implications relating to movement [literal and metaphoric] and engagement are explored.***Você pode me ouvir? - Acessando a voz da criança com Autismo e seus pais***O objetivo deste artigo é acessar as vozes de crianças com Transtorno do Espectro Autista (TEA) e de seus pais. Este artigo aborda estruturas conceituais filosóficas que exploram conceitos de movimento e engajamento como forma de dar voz a crianças e pais. Estudos de caso qualitativos e longitudinais foram conduzidos. Entrevistas semiestruturadas [n = 83] foram realizadas com as partes interessadas, incluindo os pais. Crianças com e sem o diagnóstico de TEA envolveram-se em intervenções baseadas nas Artes Criativas. A autoetnografia viva foi considerada um princípio metodológico, estabelecendo conectividade entre a vida e a pesquisa, o eu e os outros, fornecendo uma janela através da qual o mundo interno dos pais foi interpretado e compreendido. Esta pesquisa permitiu que crianças e pais explorassem seus mundos e deliberassem sobre as áreas que afetaram suas vidas. O valor potencial do uso das Artes Criativas como meio de envolver as crianças com Autismo é discutido. Implicações relacionadas ao movimento [literal e metafórico] e engajamento são exploradas.Palavras-chave: Engajamento; Crianças com Autismo, Voz da criança; Voz dos pais; Inclusão, Movimento; Imitação; Teatro de Fantoches
Towards Implementation of an Early Intervention Model by a Paraguayan Organization
Authors: McWilliam R. A. , García-Grau Pau
Published: May 2020

Implementation science has been developed to help understand why evidence-based practices are not adopted as rapidly as they might. We describe here the process a rehabilitation center in Paraguay is undergoing to transform itself into a state-of-the-art early intervention program. We describe the organization and its contextual strengths and barriers, the model it chose to implement, and the implementation procedures it has attempted. The implications for model fidelity are highlighted, as this organization needed to make adaptations to the model as designed, to fit the particular context of its mission and the Paraguayan culture. Features of the Routines-Based Model are described.***Rumo à implementação de um modelo de intervenção precoce por uma Organização Paraguaia***A ciência da implementação foi desenvolvida para ajudar a entender as razões que levam a que as práticas baseadas na evidência não sejam adotadas pelos profissionais tão rapidamente quanto deveriam ser. Descrevemos aqui o processo de transformação que um centro de reabilitação no Paraguai está a passar se tornar num programa de intervenção precoce de última geração. Descrevemos a sua organização, os seus pontos fortes e as barreiras contextuais, o modelo que escolheu implementar e os procedimentos de implementação que utilizou. As implicações para a fidelidade do modelo são destacadas, pois a organização necessitava fazer adaptações ao modelo conforme previsto, para se ajustar ao contexto específico da sua missão e da cultura paraguaia. São descritas as características do modelo baseado nas rotinas.Palavras-chave: Ciência da implementação, centrado na família, baseada nasrotinas, funcional.