bluuebunny/crossref_metadata_2025 huggingface dataset:
An Update on Viral Hepatitis B and C in Mexico: Advances and Pitfalls in Eradication Strategies
Authors: Campos-Valdez Marina , Castro-García Manuel Alejandro , Ramos-Márquez Martha Eloísa , Gurrola-Díaz Carmen Magdalena , Salazar-Montes Adriana María , Sánchez-Orozco Laura Verónica
Published: July 2024

In Mexico, hepatitis B and C infections are a significant burden on the health system. The aim of this narrative review was to analyze the state of the art on hepatitis B and C in Mexico by searching and studying available data in academic articles and government reports and statements on epidemiology, prevention, treatment, and elimination strategies undertaken by the Mexican government. Even where the government has implemented a hepatitis B vaccination strategy to reduce its incidence, a very low proportion of people complete the vaccination schedule. Regarding hepatitis C, there is a National Elimination Program that emphasizes the importance of screening, diagnosis, and treatment focused on the population at risk. With the implementation of this program, more than a million fast tests have been carried out and the positive cases have been verified by viral load. Infected patients are tested to determine liver function, fibrosis stage, and coinfection with HBV and/or HIV. Patients without cirrhosis and/or coinfections are treated in first-level care centers, while those with cirrhosis and/or comorbidities are referred to specialists. The possibility of hepatitis C eradication in Mexico seems more likely than eradication of hepatitis B; however, major challenges remain to be overcome to reach both infections’ elimination.
Recycling and Reuse of Spent LIBs: Technological Advances and Future Directions
Authors: Lv Long , Zhou Siqi , Liu Changqi , Sun Yuan , Zhang Jubing , Bu Changsheng , Meng Junguang , Huang Yaji
Published: July 2024

Recovering valuable metals from spent lithium-ion batteries (LIBs), a kind of solid waste with high pollution and high-value potential, is very important. In recent years, the extraction of valuable metals from the cathodes of spent LIBs and cathode regeneration technology are still rapidly developing (such as flash Joule heating technology to regenerate cathodes). This review summarized the studies published in the recent ten years to catch the rapid pace of development in this field. The development, structure, and working principle of LIBs were firstly introduced. Subsequently, the recent developments in mechanisms and processes of pyrometallurgy and hydrometallurgy for extracting valuable metals and cathode regeneration were summarized. The commonly used processes, products, and efficiencies for the recycling of nickel–cobalt–manganese cathodes (NCM/LCO/LMO/NCA) and lithium iron phosphate (LFP) cathodes were analyzed and compared. Compared with pyrometallurgy and hydrometallurgy, the regeneration method was a method with a higher resource utilization rate, which has more industrial application prospects. Finally, this paper pointed out the shortcomings of the current research and put forward some suggestions for the recovery and reuse of spent lithium-ion battery cathodes in the future.
Liquid–Liquid Equilibrium of Sesame Fatty Acid (Ethyl and Methyl) Ester + Glycerol + Ethanol/Methanol Mixtures at Different Temperatures
Authors: Silva Anderson , Lopes Guilherme , Corazza Marcos , Arce Pedro , Coêlho Dayana , Meili Lucas , Carvalho Sandra , Ferreira-Pinto Leandro , Soletti João
Published: July 2024

This study aimed to investigate the liquid–liquid equilibrium (LLE) behavior of sesame fatty acid ethyl ester (FAEE) and methyl ester (FAME) in combination with glycerol and the co-solvents ethanol and methanol. FAEE and FAME were produced through the transesterification of mechanically extracted and purified sesame oil, using potassium hydroxide (KOH) as a homogeneous base catalyst. The reactions were conducted in ethanol and methanol to produce FAEE and FAME, respectively. Post-reaction, the products were separated and purified, followed by an analysis of the LLE behavior at 313.15 K and 323.15 K under atmospheric pressure (101.3 kPa). The experimental process for the miscibility analysis utilized a jacketed glass cell adapted for this study. Miscibility limits or binodal curves were determined using the turbidity-point method. Tie lines were constructed by preparing mixtures of known concentrations within the two-phase region, which allowed the phases to separate after agitation. Samples from both phases were analyzed to determine their composition. This study revealed that higher temperatures promoted greater phase separation and enhanced the biodiesel purification process. The NRTL model effectively correlated the activity coefficients with the experimental data, showing good agreement, with a root-mean-square deviation of 3.5%. Additionally, the data quality was validated using Marcilla’s method, which yielded an R2 value close to 1. Attraction factors and distribution coefficients were also calculated to evaluate the efficiency of the co-solvents as extraction agents. The findings indicated higher selectivity for methanol than for ethanol, with varying degrees of distribution among the co-solvents. These results offer significant insights into enhancing biodiesel production processes by considering the effects of co-solvents on the LLE properties of mixtures, ultimately contributing to more efficient and cost-effective biodiesel production.
α-Carbonyl Rh-Carbenoid Initiated Cascade Assembly of Diazobarbiturates with Alkylidene Pyrazolones for Synthesis of Spirofuropyrimidines
Authors: Zhang Yue , Mi Yu-Hang , Wang Kuo , Zhao Hong-Wu
Published: July 2024

Catalyzed by Rh2(esp)2 (10 mol%) and (±)-BINAP (20 mol%) in DCE at 80 °C, the cascade assembly between diazobarbiturates and alkylidene pyrazolones proceeded readily and produced spiro-furopyrimidines in 38–96% chemical yields. The chemical structure of the prepared spirofuro-pyrimidines was firmly confirmed by X-ray diffraction analysis.
MgO Modified by X2, HX, or Alkyl Halide (X = Cl, Br, or I) Catalytic Systems and Their Activity in Chemoselective Transfer Hydrogenation of Acrolein into Allyl Alcohol
Authors: Gliński Marek , Ulkowska Urszula , Kaszkur Zbigniew , Łomot Dariusz , Winiarek Piotr
Published: July 2024

A new type of catalyst containing magnesium oxide modified with various modifiers ranging from bromine and iodine, to interhalogen compounds, hydrohalogenic acids, and alkyl halides have been prepared using chemical vapor deposition (CVD) and wet impregnation methods. The obtained systems were characterized using a number of methods: determination of the concentration of X− ions, surface area determination, powder X-ray diffraction (PXRD), surface acid–base strength measurements, TPD of probe molecules (acetonitrile, pivalonitrile, triethylamine, and n-butylamine), TPD-MS of reaction products of methyl iodide with MgO, and Fourier transform infrared spectroscopy (FTIR). The catalysts’ activity and chemoselectivity during transfer hydrogenation from ethanol to acrolein to allyl alcohol was measured. A significant increase in the activity of modified MgO (up to 80% conversion) in the transfer hydrogenation of acrolein was found, while maintaining high chemoselectivity (>90%) to allyl alcohol. As a general conclusion, it was shown that the modification of MgO results in the suppression of strong basic sites of the oxide, with a simultaneous appearance of Brønsted acidic sites on its surface. Independently, extensive research on the reaction progress of thirty alkyl halides with MgO was also performed in order to determine its ability to neutralize chlorinated wastes.
Being a Postgraduate Nursing Student in Limpopo Province, South Africa: An Exploratory Study
Authors: Ntho Tshepo Albert , Ngoatle Charity , Mothiba Tebogo Maria , Hlahla Lina Sebolaisi , Phukubye Thabo Arthur , Bopape Mamare Adelaide
Published: July 2024

Research proficiencies for nurses include the ability to search for and evaluate evidence, disseminate findings, and apply findings to practice within the context of caring. Aim: This study explored the experiences of distant postgraduate nursing students in Limpopo Province, South Africa. Methods: The population consists of all students registered for postgraduation studies in a nursing programme at two South African universities in Limpopo Province. Purposive sampling was used to select 23 registered postgraduate nursing students. Data were collected through unstructured one-on-one interviews, including an audio recorder and field notes. The narrative data from interviews were analysed qualitatively through Tesch’s open coding descriptive qualitative data analysis method. Results: Three main themes emerged: the reasons behind engaging in postgraduate studies, factors impacting postgraduate studies’ success, and a description of challenges associated with conducting research. Conclusions: The students generally have varied experiences about whether or not completing a research project is a valuable learning experience. The relationship between a postgraduate student and their research supervisor is crucial to ensuring that the students advance consistently and complete their theses on time. The study will, therefore, assist HEIs offering postgraduate programmes in nursing in realising the challenges faced by students and coming up with strategies to combat the challenges.
The World of Immunotherapy Needs More Than PD-1/PD-L1—Two of the New Kids on the Block: LAG-3 and TIGIT
Authors: Gama João Martins , Teixeira Paulo , Caetano Oliveira Rui
Published: July 2024

Immunotherapy has paved the way for the development of solid tumor new treatments in the last decade. The approval of immune checkpoint inhibitors such as anti PD-1/PD-L1 provided a revolution with optimal results. However, a considerable proportion of patients experience adverse therapeutic effects, and up to 50% may develop secondary resistance in the first three to five years. This has prompted the need for identifying new targets for immunotherapy that have good tolerance and biosafety and, of course, good tumoral response, either alone or in combination. Two of these new targets are the Lymphocyte-activation gene 3 (LAG-3) and the T cell immunoglobulin and ITIM domain (TIGIT). They are responsible for several interactions with the immune system, prompting an immunosuppressive phenotype in the tumor microenvironment. Both LAG-3 and TIGIT can be druggable, alone or in combination with anti-PD-1/PD-L1, with rather safe profiles making them attractive. In this review, we highlight some of the immune mechanisms of TIGIT and LAG-3 and their detection by immunohistochemistry, providing some insight into their use in the clinical setting.
Successful Transmammary Treatment of Babesia gibsoni Infection in Newborn Puppies after the Administration of Malarone®, Azithromycin, and Artesunate to a Lactating Dam
Authors: Karasová Martina , Blaňarová Lucia , Tóthová Csilla , Hrčková Gabriela , Kisková Terézia , Ševčíková Zuzana , Revajová Viera , Nagy Oskar , Víchová Bronislava
Published: July 2024

Babesia gibsoni is a parasitic protozoan transmitted through tick bites and can cause severe disease in dogs. It can also be transmitted through direct contact with infected blood during dog fights, blood transfusions, and from dam to offspring during the perinatal period, resulting in stillborn or dead newborn puppies. This study aimed to determine the incidence of infection, the viability of newborn puppies, and the degree of B. gibsoni transmission from infected dam to offspring during pregnancy and lactation. Using PCR-based molecular methods, B. gibsoni infection in a pregnant American Pit Bull Terrier and her newborn puppies was confirmed. The incidence of B. gibsoni infection in the litter reached 75%. Out of eight puppies, six were infected with B. gibsoni, and one died. A therapeutic protocol comprising Malarone®, azithromycin, and artesunate was administered to a lactating B. gibsoni-positive bitch. By day 77 after birth, three out of five positive puppies showed negative PCR tests for B. gibsoni, indicating successful treatment through breast milk during nursing. In the two remaining positive puppies, therapy was started and parasitemia was successfully eliminated.
Exploring the Perceptions and Behaviours of UK Prescribers Concerning Novel Lipid-Lowering Agent Prescriptions: A Qualitative Study
Authors: Baig Sarah , Mughal Shahrauz , Murad Yousuf , Virdee Mandeep , Jalal Zahraa
Published: July 2024

Reducing low-density lipoprotein cholesterol levels lowers the risk of atherosclerotic cardiovascular disease. With the current and future portfolios of emerging lipid-lowering therapies included in various national and international guidelines, the objectives of this study were (i) to investigate the perceptions of UK prescribers’, including doctors, pharmacists, and nurses, on current lipid management for cardiovascular diseases and prescriptions of novel lipid-lowering therapies, and (ii) to explore the challenges and facilitating factors of prescribing novel lipid-lowering therapies through qualitative interviews. Qualitative semi-structured interviews with twelve medical and non-medical prescribers were conducted, around 20–30 min in length. The interviews were audio-recorded and transcribed on an online platform. A thematic analysis was deployed. Four major themes emerged from the analysis: (1) prescribing barriers; (2) prescribing enablers; (3) inter-profession variability; and (4) health literacy. These themes highlighted the contrast between the need for optimal shared decision making and the various constraints in practice. Participants expressed their inexperience with novel lipid-lowering therapies and acknowledged the requirement and importance of these agents for primary cardiovascular disease prevention. Participants recognised confidence and competence as key drivers for prescribing therapies and welcomed further education and training to enhance their skillset. Patients’ misconceptions towards current lipid-lowering therapies contributed to their refusal of newer agents, highlighting a requirement to improve patient education. Targeting communities through awareness campaigns was identified as a viable solution.
Design of an Airborne Low-Light Imaging System Based on Multichannel Optical Butting
Authors: Peng Jianwei , Yang Hongtao , Lei Yangjie , Yu Wanrong , Chen Weining , Zhang Guangdong
Published: July 2024

For the purpose of achieving long-range, high-resolution, and ultra-wide-swath airborne earth imaging at extremely low-light levels (0.01 Lux), a low-light imaging system built on multi-detector optical butting was researched. Having decomposed the system’s specifications and verified its low-light imaging capability, we proposed to employ an optical system with a large relative aperture and low distortion and achieve imaging through the field-of-view (FOV) butting facilitated by eight 1080P high-sensitivity scientific complementary metal-oxide semiconductor (SCMOS) detectors. This paper elaborates on the design concept of the mechanical configuration of the imaging system; studies the calculation method of the structural parameters of the reflection prism; provides mathematical expressions for geometric parameters, such as the length and width of the splicing prism; and designs in detail the splicing structure of six reflection prisms for eight-channel beam splitting. Based on the design and computational results, a high-resolution, wide-swath imaging system for an ambient illuminance of 0.01 Lux was developed. Exhibiting a ground sampling distance (GSD) of 0.5 m (at a flight height of 5 km), this low-light imaging system keeps the FOV overlap ratio between adjacent detectors below 3% and boasts an effective image resolution of 4222 × 3782. The results from flight testing revealed that the proposed imaging system is capable of generating wide-swath, high-contrast resolution imagery under airborne and low-light conditions. As such, the way the system is prepared can serve as a reference point for the development of airborne low-light imaging devices.
Morpho- and Chemotyping of Holopelagic Sargassum Species Causing Massive Strandings in the Caribbean Region
Authors: Kergosien Nolwenn , Helias Mathieu , Le Grand Fabienne , Cérantola Stéphane , Simon Gaëlle , Nirma Charlotte , Thibaut Thierry , Berline Léo , Changeux Thomas , Blanfuné Aurélie , Connan Solène , Stiger-Pouvreau Valérie
Published: July 2024

The specific identification of three major morphotypes of the tropical holopelagic Sargassum species causing massive strandings on the African and Caribbean coastlines was attempted by morphological characterisation as well as quantitative and qualitative analyses of several metabolites. Of the 25 morphological variables studied on 208 samples from the North Atlantic Ocean, 22 were used to establish a dichotomous identification key, allowing without any doubt the identification of each morphotype based on their morphological criteria alone. We also attempted to differentiate morphotypes using chemical fingerprintings (HR-MAS NMR) and markers by analysing pigment level and composition using High Pressure Liquid Chromatography, terpene profiles by Thin Layer Chromatography, phenolic compound levels by the Folin-Ciocalteu assay and structures by 2D Nuclear Magnetic Resonance spectroscopy, and fatty acid composition by Gas Chromatography. While pigment level and composition, terpene profiles, and phenolic contents were not discriminating, quantification of eight fatty acids enabled the differentiation of the three morphotypes. Furthermore, phlorotannin purification permitted their structural characterisation allowing discrimination between the three morphotypes. Our study highlights the potential of the free fatty acid profile and phlorotannin structure as good chemomarkers in order to discriminate between the three morphotypes of holopelagic Sargassum.
Chemical Composition of Volatile and Extractive Organic Compounds in the Inflorescence Litter of Five Species of Woody Plants
Authors: Isidorov Valery A. , Masłowiecka Jolanta
Published: July 2024

The decomposition of plant litter, most of which is found in forests, is an important element of the global carbon cycle, as a result of which carbon enters the atmosphere in the form of not only CO2 but also volatile organic compounds (VOCs). Although the formation of litter is associated with autumn cooling, in the spring, there is a very intense fall of faded inflorescences of woody plants. This study examined the chemical composition of the litter and VOCs emitted from decaying inflorescences of four species of forest-forming trees: silver birch, European hornbeam, black alder and aspen. All litter emissions consisted of 291 VOCs, mainly terpenes actively participating in atmospheric processes. The detection of a number of typical mushroom metabolites, such as 1-octen-3-ol, known as “mushroom alcohol”, and alkyl sulphides, suggests that inflorescence-derived VOCs are a mixture of components of plant and microbial origin. In methanol extracts of the fallen inflorescences of all types, 263 organic compounds were identified, the majority of which were related to carbohydrates. Their share in the extracts was 72–76%. In general, the composition of the extractive compounds indicates the easy availability of this material for assimilation by various types of destructors.
Investigating the Chemical Profile of Underexplored Parts of Dipteryx alata (Baru) Using the PS–MS Technique
Authors: Nunes Bruna Vieira , Silva Viviane Dias Medeiros , Ramos Ana Luiza Coeli Cruz , Coelho Talvane , Melo Angelita Cristine de , Ferreira Ricardo Manuel de Seixas Boavida , Augusti Rodinei , Lucena Reinaldo Farias Paiva de , Melo Júlio Onésio Ferreira , Araújo Raquel Linhares Bello de
Published: July 2024

The baru (Dipteryx alata Vog.), a fruit native to the Cerrado biome, is well-known for its almonds, which are extensively exploited and exported. Unfortunately, the remaining parts of this fruit are often discarded. This study investigates the fixed chemical constituents of the baru, including the bark, pulp, endocarp, and almonds, using the PS–MS technique in positive and negative ionization modes. Notably, this research presents the first chemical profile of baru almonds in both their raw and roasted states. The analysis identified 57 compounds reported for the first time in a baru and 24 common compounds. The majority of these compounds are classified as flavonoids. In both ionization modes, the peel exhibited a higher proportion of phenolic compounds, although the chemical compounds varied among the peel, pulp, almond, and endocarp. These findings highlight the perspective of bioeconomy and biotechnology. By staggering baru fruit production alongside extractivists, we can optimize the utilization of all parts of the fruit. Furthermore, given the knowledge of the biological properties of flavonoids and the baru composition, we recommend additional studies to analyze their potential in preventing chronic non-communicable diseases.
PagbHLH35 Enhances Salt Tolerance through Improving ROS Scavenging in Transgenic Poplar
Authors: Wang Shuang , Dong Liben , Yao Wenjing , Jiang Tingbo
Published: July 2024

The bHLH transcription factor family plays crucial roles in plant growth and development and their responses to adversity. In this study, a highly salt-induced bHLH gene, PagbHLH35 (Potri.018G141600), was identified from Populus alba × P. glandullosa (84K poplar). PagbHLH35 contains a highly conserved bHLH domain within the region of 52–114 amino acids. A subcellular localization result confirmed its nuclear localization. A yeast two-hybrid assay indicated PagbHLH35 lacks transcriptional activation activity, while a yeast one-hybrid assay indicated it could specifically bind to G-box and E-box elements. The expression of PagbHLH35 reached its peak at 12 h and 36 h time points under salt stress in the leaves and roots, respectively. A total of three positive transgenic poplar lines overexpressing PagbHLH35 were generated via Agrobacterium-mediated leaf disk transformation. Under NaCl stress, the transgenic poplars exhibited significantly enhanced morphological and physiological advantages such as higher POD activity, SOD activity, chlorophyll content, and proline content, and lower dehydration rate, MDA content and hydrogen peroxide (H2O2) content, compared to wild-type (WT) plants. In addition, histological staining showed that there was lower ROS accumulation in the transgenic poplars under salt stress. Moreover, the relative expression levels of several antioxidant genes in the transgenic poplars were significantly higher than those in the WT. All the results indicate that PagbHLH35 can improve salt tolerance by enhancing ROS scavenging in transgenic poplars.
Adaptation to Third-Party Payments: Statistical Analysis of Digital Donations Made to Donglin Monastery
Authors: Liu Qi
Published: July 2024

This paper explores the adaptations Buddhism has made to digital payment methods in the context of the Chinese mainland. To provide the audience with a relatively comprehensive understanding of the general context in which the new method of donation is applied, this paper first introduces the development and digital landscape of the internet and third-party payments in the Chinese mainland. Then, statistical analysis is used to make large-scale claims by analyzing 1328 donation records made to Donglin Monastery in Mount Lu with the statistical software SPSS to determine whether the digital donation method is linked to the purpose of donations, or the amount of money being donated, and to what extent it substitutes for traditional donation methods.
The Relationship between the Level of Religiousness of the Christian Orthodox Female Students of Teachers’ Education Faculties in Serbia and Their Attitudes towards Orthodox-Moral Issues
Authors: Petrović Jelena R. , Šuvaković Uroš V. , Nikolić Ivko A.
Published: July 2024

Religion is a complex construct that defines not only the historical and social identity of a nation, but also the personal identity of an individual. The attitude towards religion can be conditioned by tradition, political ideology, true faith, education, etc. In our research, we have tried to establish the level of religiousness of the female students of teacher education faculties in Serbia, belonging to the Orthodox Christianity as the dominant confession in Serbia. We examined their attitudes towards some of the moral challenges encountered by believers, including abortion, prostitution, same-sex marriages, the use of cannabis, and euthanasia. Using a snowball non-discriminative online sample of 336 female Orthodox students, we found that the students assessed themselves as above-average religious and that out of three dimensions of religiousness measured in the questionnaire, the lowest scores were recorded for the dimension of the effect of faith on their behavior. The study showed that the level of religiousness is a good predictor of attitudes towards abortion, prostitution, and same-sex marriages, but not towards the use of cannabis. Moreover, religiousness and attitudes towards prostitution are positively correlated, which is directly opposite to religious teachings. This is why a question arises as to whether we can speak about a return to faith or merely a return to the traditional model of manifesting the religious as an antipode to the secular organization in force until 1989. The results of our research point to the latter conclusion.
Development of the Black–Scholes Model for Determining Insurance Premiums to Mitigate the Risk of Disaster Losses Using the Principles of Mutual Cooperation and Regional Economic Growth
Authors: Purwandari Titi , Hidayat Yuyun , Sukono  , Kalfin  , Ibrahim Riza Andrian , Subiyanto
Published: July 2024

The frequency and economic damage of natural disasters have increased globally over the last two decades due to climate change. This increase has an impact on the disaster insurance field, particularly in the calculation of premiums. Many regions have a shortcoming in employing insurance because the premium is too high compared with their budget allocation. As one of the solutions, the premium calculation can be developed by applying the cross-subsidies mechanism based on economic growth. Therefore, this research aims to develop premium models of natural disaster insurance that uniquely involve two new variables of an insured region: cross-subsidies and the economic growth rate. Another novelty is the development of the Black–Scholes model, considering the two new variables, and it is used to formulate the premium model. Following the modeling process, this study uses the model to estimate the premiums for natural disaster insurance in each province of Indonesia. The estimation results show that all new variables involved in the model novelties significantly affect the premiums. This research can be used by insurance companies to determine the premium of natural disaster insurance, which involves cross-subsidies and economic growth.
Anti-IgG Doped Melanin Nanoparticles Functionalized Quartz Tuning Fork Immunosensors for Immunoglobulin G Detection: In Vitro and In Silico Study
Authors: Gürcan Dilhan , Baysoy Engin , Kaleli-Can Gizem
Published: July 2024

The quartz tuning fork (QTF) is a promising instrument for biosensor applications due to its advanced properties such as high sensitivity to physical quantities, cost-effectiveness, frequency stability, and high-quality factor. Nevertheless, the fork’s small size and difficulty in modifying the prongs’ surfaces limit its wide use in experimental research. Our study presents the development of a QTF immunosensor composed of three active layers: biocompatible natural melanin nanoparticles (MNPs), glutaraldehyde (GLU), and anti-IgG layers, for the detection of immunoglobulin G (IgG). Frequency shifts of QTFs after MNP functionalization, GLU activation, and anti-IgG immobilization were measured with an Asensis QTF F-master device. Using QTF immunosensors that had been modified under optimum conditions, the performance of QTF immunosensors for IgG detection was evaluated. Accordingly, a finite element method (FEM)-based model was produced using the COMSOL Multiphysics software program (COMSOL License No. 2102058) to simulate the effect of deposited layers on the QTF resonance frequency. The experimental results, which demonstrated shifts in frequency with each layer during QTF surface functionalization, corroborated the simulation model predictions. A modelling error of 0.05% was observed for the MNP-functionalized QTF biosensor compared to experimental findings. This study validated a simulation model that demonstrates the advantages of a simulation-based approach to optimize QTF biosensors, thereby reducing the need for extensive laboratory work.
A Novel Joint Motion Compensation Algorithm for ISAR Imaging Based on Entropy Minimization
Authors: Li Jishun , Zhang Yasheng , Yin Canbin , Xu Can , Li Pengju , He Jun
Published: July 2024

Space targets move in orbit at a very high speed, so in order to obtain high-quality imaging, high-speed motion compensation (HSMC) and translational motion compensation (TMC) are required. HSMC and TMC are usually adjacent, and the residual error of HSMC will reduce the accuracy of TMC. At the same time, under the condition of low signal-to-noise ratio (SNR), the accuracy of HSMC and TMC will also decrease, which brings challenges to high-quality ISAR imaging. Therefore, this paper proposes a joint ISAR motion compensation algorithm based on entropy minimization under low-SNR conditions. Firstly, the motion of the space target is analyzed, and the echo signal model is obtained. Then, the motion of the space target is modeled as a high-order polynomial, and a parameterized joint compensation model of high-speed motion and translational motion is established. Finally, taking the image entropy after joint motion compensation as the objective function, the red-tailed hawk–Nelder–Mead (RTH-NM) algorithm is used to estimate the target motion parameters, and the joint compensation is carried out. The experimental results of simulation data and real data verify the effectiveness and robustness of the proposed algorithm.
Noncooperative Spectrum Sensing Strategy Based on Recurrence Quantification Analysis in the Context of the Cognitive Radio
Authors: Kadjo Jean-Marie , Yao Koffi Clément , Mansour Ali , Le Jeune Denis
Published: July 2024

This paper addresses the problem of noncooperative spectrum sensing in very low signal-to-noise ratio (SNR) conditions. In our approach, detecting an unoccupied bandwidth consists of detecting the presence or absence of a communication signal on this bandwidth. Digital communication signals may contain hidden periodicities, so we use Recurrence Quantification Analysis (RQA) to reveal the hidden periodicities. RQA is very sensitive and offers reliable estimation of the phase space dimension m or the time delay τ. In view of the limitations of the algorithms proposed in the literature, we have proposed a new algorithm to simultaneously estimate the optimal values of m and τ. The new proposed optimal values allow the state reconstruction of the observed signal and then the estimation of the distance matrix. This distance matrix has particular properties that we have exploited to propose a Recurrence-Analysis-based Detector (RAD). The RAD can detect a communication signal in a very low SNR condition. Using Receiver Operating Characteristic curves, our experimental results corroborate the robustness of our proposed algorithm compared with classic widely used algorithms.
Preparation and Printing Performance of Visible Light Photochromic Paper Based on PMoA-PWA/ZnO/PVP Composite
Authors: Zhao Wanqing , Zhao Hongmei , Feng Wei , Zhao Honggang
Published: July 2024

The recyclable paper based on photochromic materials not only reduces the pollution in the paper manufacture process, but also reduces the pollution caused by the use of ink, which receives wide attention. In this paper, a series of phosphomolybdic acid–phosphotungstic acid/ZnO/polyvinylpyrrolidone (PMoA-PWA/ZnO/PVP) hybrid films, which had different ratio of PMoA/PWA, was prepared by the ultrasonic composite method. The results indicated that the hybrid film prepared when the ratio of PMoA to PWA was 3 had the best photochromic performance. In this system, ZnO was the photosensitizer, while PMoA/PWA was the chromophore. The photochromic mechanism of the PMoA-PWA/ZnO/PVP hybrid film was based on the photogenerated electron transfer mechanism. ZnO generated photoelectron under the excitation of visible light, then PMoA and PWA obtained the photoelectron and produced photoreduction reaction to generate heteropolyblue. The visible light photochromic paper was prepared by loaded PMoA-PWA/ZnO/PVP hybrid film (A3) on A4 paper. Application tests showed that the prepared paper had extremely stable, excellent and reversible visible light photochromic properties, whether it was printing patterns or words, and could replace ordinary paper to realize the reuse of paper.
Application of High-Surface Tension and Hygroscopic Ionic Liquid-Infused Nanostructured SiO2 Surfaces for Reversible/Repeatable Anti-Fogging Treatment
Authors: Nakamura Satoshi , Wassgren Jerred , Sugie Sayaka , Hozumi Atsushi
Published: July 2024

Anti-fogging coatings/surfaces have attracted much attention lately because of their practical applications in a wide variety of engineering fields. In this study, we successfully developed transparent anti-fogging surfaces using a non-volatile and hygroscopic ionic liquid (IL), bis(hydroxyethyl)dimethylammonium methanesulfonate ([BHEDMA][MeSO3]), with a high surface tension (HST, 66.4 mN/m). To prepare these surfaces, a layer of highly transparent, superhydrophilic silica (SiO2) nano-frameworks (SNFs) was first prepared on a glass slide using candle soot particles and the subsequent chemisorption of tetraethoxysilane (TEOS). This particulate layer of SNFs was then used as the support for the preparation of the [BHEDMA][MeSO3] layer. The resulting IL-infused SNF-covered glass slide was highly transparent, superhydrophilic, hygroscopic, and had self-healing and reasonable reversible/repeatable anti-fogging/frosting properties. This IL-infused sample surface kept its excellent anti-fogging performance in air for more than 8 weeks due to the IL’s non-volatile, HST, and hygroscopic nature. In addition, even if the water absorption limit of [BHEDMA][MeSO3] was reached, the anti-fogging properties could be fully restored reversibly/repeatably by simply leaving the samples in air for several tens of minutes or heating them at 100 °C for a few minutes to remove the absorbed water. Our IL-based anti-fogging surfaces showed substantial improvement in their abilities to prevent fogging when compared to other dry/wet (super)hydrophobic/(super)hydrophilic surfaces having different surface geometries and chemistries.
Smartphone-Based Citizen Science Tool for Plant Disease and Insect Pest Detection Using Artificial Intelligence
Authors: Christakakis Panagiotis , Papadopoulou Garyfallia , Mikos Georgios , Kalogiannidis Nikolaos , Ioannidis Dimosthenis , Tzovaras Dimitrios , Pechlivani Eleftheria Maria
Published: July 2024

In recent years, the integration of smartphone technology with novel sensing technologies, Artificial Intelligence (AI), and Deep Learning (DL) algorithms has revolutionized crop pest and disease surveillance. Efficient and accurate diagnosis is crucial to mitigate substantial economic losses in agriculture caused by diseases and pests. An innovative Apple® and Android™ mobile application for citizen science has been developed, to enable real-time detection and identification of plant leaf diseases and pests, minimizing their impact on horticulture, viticulture, and olive cultivation. Leveraging DL algorithms, this application facilitates efficient data collection on crop pests and diseases, supporting crop yield protection and cost reduction in alignment with the Green Deal goal for 2030 by reducing pesticide use. The proposed citizen science tool involves all Farm to Fork stakeholders and farm citizens in minimizing damage to plant health by insect and fungal diseases. It utilizes comprehensive datasets, including images of various diseases and insects, within a robust Decision Support System (DSS) where DL models operate. The DSS connects directly with users, allowing them to upload crop pest data via the mobile application, providing data-driven support and information. The application stands out for its scalability and interoperability, enabling the continuous integration of new data to enhance its capabilities. It supports AI-based imaging analysis of quarantine pests, invasive alien species, and emerging and native pests, thereby aiding post-border surveillance programs. The mobile application, developed using a Python-based REST API, PostgreSQL, and Keycloak, has been field-tested, demonstrating its effectiveness in real-world agriculture scenarios, such as detecting Tuta absoluta (Meyrick) infestation in tomato cultivations. The outcomes of this study in T. absoluta detection serve as a showcase scenario for the proposed citizen science tool’s applicability and usability, demonstrating a 70.2% accuracy (mAP50) utilizing advanced DL models. Notably, during field testing, the model achieved detection confidence levels of up to 87%, enhancing pest management practices.
Added-Value of Cotton Textile Waste for Nonwoven Applications
Authors: Rodrigues Lúcia , Marques Rita , Dias Juliana C. , Magalhães Beatriz , Santos Anabela , Amorim Cláudia , Carta Ana Margarida , Pinto Paula , Silva Carla J.
Published: July 2024

Due to the continuous optimization of cutting plans, the cotton scrap size resulting from the cutting of components for clothing production (post-industrial residues) is often considered insufficient to obtain fibres with the proper length to produce a new yarn through mechanical recycling processes; so it is important to search for other applications for these wastes. In this context, small pieces of cotton were submitted to a shredding process to obtain recycled fibres. Cotton small pieces and recycled fibres were then submitted to a refining process to achieve refined fibres. Using these materials alone and in blends with refined and unrefined bleached eucalyptus kraft pulp (BEKP), wet-laid nonwovens were developed and characterized. An analysis of the results revealed that the replacement of unrefined BEKP by 70% cotton waste fibres in wet-laid nonwovens, reducing the use of virgin raw material, enhances the structures’ mechanical properties by 80% and 14%, for small pieces or recycled fibres, respectively. Additionally, refining small pieces of cotton seems to be more promising than refining recycled fibres, because less steps are required to obtain wet-laid nonwovens with better mechanical properties. These results highlight the potential of this approach to be explored further for different products and end applications.
Personal Exposure to Sulfuric Acid in the Electroplating Industry: Development and Validation of a Predictive Model
Authors: Wang Austin B. , Chuang Kai-Jen , Wang Ven-Shing , Chang Ta-Yuan
Published: July 2024

This study aimed to measure personal exposure to sulfuric acid in the electroplating industry to establish a predictive model and test its validation. We collected indoor air parameters and related information from four electroplating plants. Silica gel sorbents were used to collect air samples using high-performance ion chromatography. We collected air samples from three plants (i.e., Plant B, Plant C, and Plant D) and applied multiple linear regressions to build a predictive model. Eight samples collected from the fourth plant (i.e., Plant A) were used to validate the model. A total of 41 samples were collected with a mean of 25.0 ± 9.8 μg/m3 (range 12.1–51.7 μg/m3) in this study, including Plant A (8 samples, 17.5 ± 2.8 μg/m3, 13.0–22.0 μg/m3), Plant B (11 samples, 36.5 ± 9.7 μg/m3, 23.1–51.7 μg/m3), Plant C (11 samples, 16.4 ± 1.7 μg/m3, 12.1–17.8 μg/m3), and Plant D (11 samples, 27.4 ± 1.7 μg/m3, 24.1–29.9 μg/m3). Plant B was significantly higher in sulfuric acid than the other plants. Workers from the electroplating process plants were exposed to sulfuric acid at 29.0 ± 11.5 μg/m3. The predictive model for personal exposure to sulfuric acid fit the data well (r2 = 0.853; adjusted r2 = 0.837) and had an accuracy of 5.52 μg/m3 (bias ± precision; 4.98 ± 2.38 μg/m3), validated by the personal sampling of the fourth plant. This study observed that sulfuric acid exposure was lower than the permissible exposure level of 1000 μg/m3 in Taiwan and the United States, and only two samples were lower than the European Union standard of 50 μg/m3. The developed model can be applied in epidemiological studies to predict personal exposure to sulfuric acid in plants using electroplating.
Advancing Vaccinology Capacity: Education and Efforts in Vaccine Development and Manufacturing across Africa
Authors: Sinumvayo Jean Paul , Munezero Pierre Celestin , Tope Adegboyega Taofeek , Adeyemo Rasheed Omotayo , Bale Muritala Issa , Nyandwi Jean Baptiste , Haakuria Vetjaera Mekupi , Mutesa Leon , Adedeji Ahmed Adebowale
Published: July 2024

Africa, home to the world’s second-largest population of approximately 1.3 billion, grapples with significant challenges in meeting its medical needs, particularly in accessing quality healthcare services and products. The continent faces a continuous onslaught of emerging infectious diseases, exacerbating the strain on its already fragile public health infrastructure. The COVID-19 crisis highlighted the urgency to build local vaccine production capacity and strengthen the health infrastructure in general. The risks associated with a heavy reliance on imported vaccines were exposed during the COVID-19 pandemic, necessitating the need to nurture and strengthen the local manufacturing of vaccines and therapeutic biologics. Various initiatives addressing training, manufacturing, and regulatory affairs are underway, and these require increasing dedicated and purposeful financial investment. Building vaccine manufacturing capacity requires substantial investment in training and infrastructure. This manuscript examines the current state of education in vaccinology and related sciences in Africa. It also provides an overview of the continent’s efforts to address educational needs in vaccine development and manufacturing. Additionally, it evaluates the initiatives aimed at strengthening vaccine education and literacy, highlighting successful approaches and ongoing challenges. By assessing the progress made and identifying the remaining obstacles, this review offers insights into how Africa can enhance its vaccine manufacturing capacity to respond to vaccine-preventable disease challenges.
STRIDE-Based Cybersecurity Threat Modeling, Risk Assessment and Treatment of an In-Vehicle Infotainment System
Authors: Das Popy , Asif Md. Rashid Al , Jahan Sohely , Ahmed Kawsar , Bui Francis M. , Khondoker Rahamatullah
Published: July 2024

In modern automobiles, the infotainment system is crucial for enhancing driver and passenger capabilities, offering advanced features such as music, navigation, communication, and entertainment. Leveraging Wi-Fi, cellular networks, NFC, and Bluetooth, the system ensures continuous internet connectivity, providing seamless access to information. However, the increasing complexity of IT connectivity in vehicles raises significant cybersecurity concerns, including potential data breaches and exposure of sensitive information. To enhance security in infotainment systems, this study applied component-level threat modeling to a proposed infotainment system using the Microsoft STRIDE model. This approach illustrates potential component-level security issues impacting privacy and security concerns. The study also assessed these impacts using SAHARA and DREAD risk assessment methodologies. The threat modeling process identified 34 potential security threats, each accompanied by detailed information. Moreover, a comparative analysis is performed to compute risk values for prioritizing treatment, followed by recommending mitigation strategies for each identified threat. These identified threats and associated risks require careful consideration to prevent potential cyberattacks before deploying the infotainment system in automotive vehicles.
Detection of Serum IgG Specific for Brachyspira pilosicoli and “Brachyspira canis” in Dogs
Authors: Gothe Julia , Horn Matthias , Baums Christoph G. , Heilmann Romy M. , Schrödl Wieland
Published: July 2024

Brachyspira pilosicoli (B. pilosicoli) is a pathogen in pigs, poultry, and humans causing colitis, diarrhea, and poor growth rates. Its role as a canine pathogen is controversial, and the seroprevalence of specific IgG antibodies against B. pilosicoli in dogs is unknown. A further, not yet officially recognized Brachyspira species in dogs is “Brachyspira canis” (“B. canis“), which is proposed to be apathogenic. This study evaluates enzyme-linked immunosorbent assays (ELISAs) measuring serum IgG antibodies specific for B. pilosicoli or “B. canis” and investigates levels of specific IgG antibodies against B. pilosicoli and “B. canis” in a cohort of clinical patients presented at an animal referral clinic. These ELISAs use detergent-extracted antigens from B. pilosicoli and “B. canis”. To increase analytic specificity, we precipitated the antigens with trichloroacetic acid (TCA) to isolate and concentrate the respective protein fraction. Our results indicate that a large number of serum IgG antibodies bind to shared epitopes of detergent-extracted antigens of the two spirochaetes. Our data also suggest that dogs might not only carry B. pilosicoli but also have “B. canis”-specific serum IgG antibodies.
Modeling and Evaluation of a Multi-Stable Hybrid Energy Harvester
Authors: Li Haining , Liu Kefu , Deng Jian
Published: July 2024

This article develops a multi-stable hybrid energy harvester (MSHEH) which consists of a piezoelectric energy harvester (PEH) and an electromagnetic energy harvester (EMEH). By tuning two parameters, the MSHEH can achieve a mono-stable, bi-stable, and tri-stable state, respectively. A numerical procedure is developed to compute the EMEH’s transduction factor. The obtained result is validated experimentally. Using the equivalent magnetic 2-point dipole theory, the restoring force model of the magnetic spring is established. The obtained model is verified experimentally. The energy harvesting performances of the MSHEH under the four different configurations (linear, mono-stable, bi-stable and tri-stable) subjected to frequency sweep excitations are evaluated by simulation and validated by experiment. The comparative analysis focuses on power output, accumulated harvested energy, and effective energy-harvesting bandwidth. The optimum load resistances are investigated by Pareto front optimizations. The following key findings are obtained. When subjected to high-level frequency sweep excitation, the tri-stable configuration exhibits the widest frequency bandwidth and the highest total accumulated harvested energy. When subjected to low-level frequency sweep excitation, the bi-stable configuration is more efficient in energy harvesting. The best performance trade-off between the PEH and EMEH can be achieved by selecting the optimum load resistances properly.