bluuebunny/crossref_metadata_2025 huggingface dataset:
Adaptive Management in Education: a New Role of the Teacher of Higher Education
Authors: Luchaninova Olga P.
Published: February 2020

The article analyzes the new role of the teacher of a modern institution of higher education, points out the relevance of solving the problem of adaptive management in education. Attention is drawn to the managerial culture of the teacher, his readiness for changes in himself and the educational process. It is emphasized that the teacher must prepare not only the future professional specialist, but also a person with “soft skills” that can empathize, lead, bear responsibility for independently made decisions. Such preparation requires the teacher to rethink his role in the educational process and readiness for qualitative changes, primarily in himself. The teacher as a manager in education should be the organizer of the innovation process, a professional and a person. Models of teaching a teacher as a coach, facilitator, mentor, tutor are described. The necessity of a new role of a teacher in the process of adaptation to requirements and changes in society is substantiated.
The Development of Students' Emotional Intelligence in English Lessons as a Factor in their Adaptation to Modern Living Conditions
Authors: Humeniuk Iryna Bol.
Published: February 2020

The article deals with the importance of the development of students` emotional intelligence in English lessons as a factor in their adaptation to modern living conditions, to activities in a rapidly changing world.The necessity to study and use emotions in the lesson to reveal the emotional potential of the participants of the educational process and develop the emotional intelligence in them at different levels of learning is justified. It is noted that many social, psychological and physiological deviations are connected with a strong load on the nervous system, the human psyche and the person`s inability to adapt to modern conditions of life creates a problem and complicates life.It is emphasized that when learning a language, we take into consideration not only the students` ability, level of their intellect, but also the emotional sphere, the psychological atmosphere in which the educational process takes place, we use different strategies of emotional intelligence development, create a microclimate in the lessons that will promote formation of positive motivation for learning a foreign language, the learning will be more successful and students will develop the ability to analyze their own and their companions` emotional state and actions, think and make decisions, act decisively and correctly in unexpected or difficult life situations, that is, to show adaptive behavior in emotional situations. It was also noted that the question of the importance of the development of emotional intelligence in the study of language was interesting not only for psychologists, but also for educators. A large number of scientists from various fields both in Ukraine and abroad research this problem. Knowledge and emotional-value components of the educational process in English can be realized through properly selected material, forms of work, kinds and types of exercises.The article presents forms, methods and means of organizing the educational process at different levels of learning that affect the development of the emotional component, contribute to the effectiveness of the English language learning process and the creation of a positive emotional atmosphere in the classroom. It is concluded that emotional intelligence is an important component of personality development that can be developed and improved throughout the study period.Emotional intelligence cannot be viewed without child's cognitive activity. Holistic education is the unity of emotional and intellectual spheres. It is impossible to form a person capable of adaptation in the modern life without it.
Regional Innovation Policy on Sustainability: Essence, Features and Tasks
Authors: Averkyna Maryna F. , Karlova Olena An.
Published: February 2020

The article is devoted to revealing the essence, features and tasks of regional innovation policy for the development of innovations based on sustainability, active introduction of new, resource-saving technologies in the region's economy, reduction of consumption of non-renewable resources. Regional innovation policy should be seen as part of a regional sustainable development policy. Separation of a particular direction is due to the significant economic, environmental, and social effects that innovative technologies. The subjects of regional policy are the authorities of the state, regional and local levels, in particular: state and local authorities, local self-government bodies, territorial communities that will provide innovations in the region.

At the same time, it is stated that the rights and powers of state and regional authorities should be mutually agreed and divided. In such circumstances, the implementation of regional innovation policy will contribute to the best results. It is also necessary to cooperate and join forces not only with the authorities but also with businesses engaged in innovation and related industries. The authors highlight the Tasks of the Regional Innovation Policy:  the use of innovation in the regions should involve active interaction between the regions and the state, with regard to the equal use of socio-ecological and economic resources; providing prerequisites for the use of innovation, taking into account the specialization of the region; providing conditions for comprehensive training of specialists for the development of new technologies; ensuring balanced development by maximizing the use of internal resources of the region, reducing the consumption of non-renewable resources in the region; stimulation of attracting investment and credit resources, which will ensure innovation implementation; use of organizational and legal, economic tools to stimulate the use of new technologies; the use of economic methods to stimulate the use of innovation by economic entities in the region. This will help to address effectively the issues that will arise in organizing such industry in the region. As a result, it will be possible to meet the region's industrial, agricultural and consumer energy needs through the use of innovation, taking into account the region's potential, species structure and spatial differentiation, which is based on maximizing socio-ecological and economic efficiency in the context of ensuring the sustainable development of the region
Ways to Increase the Efficiency of Heating Enterprise Management Under Market Relations (on the Example of Kramatorsk Heating Network)
Authors: Dolgaleva Elena V. , Kulik Yuliia Y.
Published: February 2020

The theoretical and practical aspects of effective enterprise management are considered in the paper. The efficiency of functioning is analyzed and the general analysis of the activity of the Kramatorsk District Heating Utility (KVP) of the Kramatorsk City Council is provided. The structure of financial resources at the enterprise is investigated. Profit generation is analyzed and liquidity balance analysis of the Kramatorsk Heat Network is conducted. The main problems of this enterprise and ways of overcoming them are revealed. Recommendations are given to increase the efficiency of the management of the heat supply enterprise in terms of market relations on the example of KVP «Kramatorsk District Heating Network», namely: modernization and reconstruction of equipment; replacement of thermal networks with modern ones; replacement of old boilers with more productive new ones; insulation insulation of thermal networks; advocacy for community involvement in resource management; development of deregulation projects by the authorities; observance of the standards of accounting of the produced energy. Compliance with these guidelines will improve the quality of services provided to the analyzed company and will reduce the cost of products sold, which in turn will lead to the fact that all consumers will pay a fair price for the services received in time.

The purpose of this article is to theoretically substantiate and develop practical recommendations for the effective management of a heat supply company under market relations. The relevance of the chosen topic is due to the need for effective management of enterprises in the current state of the economy, the imperfection of theoretical, methodological and legislative support for the effective functioning of enterprises, as well as anti-crisis management, the need for systematic research on the formation of integrated anti-crisis management of enterprise finances; improvement of the state policy in the sector, improvement of the real sector of the economy, which will help to improve financial security of both individual domestic enterprises and the economy as a whole.

The scientific novelty of the obtained results is the development of recommendations for improving the efficiency of management of the heat supply company in terms of market relations. The practical value is that the results of the study can be used for other district heating systems of all types of property, which operate in the sphere of providing services to the population.
Providing of Social Safety of Population in the Conditions of Intensifying of Socio-Economic Risks
Authors: Mykhalchenko Anna
Published: February 2020

The article proves the need to ensure social security for the population, which is an important factor in the country's social stability and its national security, given the strengthening of socio-economic risks, the growth of social tension in society and the unsatisfactory social and economic development of the country. The author describes the main socio-economic risks faced by the country's population in modern conditions which lead to a high dependence of the welfare of a significant part of the population on social security and social protection.

The aim of the article is to study current trends in the socio-economic state of the country and determine its features in the context of socio-economic and political instability.

The author analyzes the current legislation of the country and the existing approaches to the definition of the concept of “social security” and concludes that the economic component is one of the important components of social security.

It has been proven that social security is largely driven by economic and social factors. According to this, the main demographic, economic and social indicators of the socio-economic development of the country are characterized. It was concluded that the conditions of social security for the country's population do not match, which is manifested in a worsening demographic situation in the country, significant stratification of society, increased poverty, inadequate social guarantees to ensure a decent standard of living, etc. It is noted that the level of well-being of the population remains extremely low, based on an analysis of its main indicators.

Based on the identified problems and the results of the study, the author outlines the directions for ensuring the social security of the country's population to increase the standard of living of the population, stimulate its economic activity and employment, which will improve the country's socio-economic situation and reduce the negative consequences of existing socio-economic risks.
Aux origines de la critique postmoderne
Authors: Ridley Simon
Published: February 2020

Dans cette reconstruction de l'importance des mouvements sociaux étudiants qui a marqué les années 1967-1969, notre tentative de reformuler les termes d'une critique variée et multipolarisée de l’institutionnalisme et de l’académisme de la connaissance est combinée à une analyse des espaces constitutifs de la relation social mouvementiste (à savoir campus: Berkeley et Nanterre). L’analogie possible entre le campus en tant qu'espace de production de connaissances et les compétences «reproductives» du savoir et l’usine en tant qu’espace de production de connaissances techniques incarnées explique également la force imaginaire d'un mouvement étudiant et ouvrier capable de marquer l’imaginaire collectif mondial et sa mémoire à ce jour.
The spreading of a counter-culture
Authors: Stuppia Paolo
Published: February 2020

This article studies the 60s-70s counterculture, taking the example of the French back-to-the-land movement that spread after the May 1968 revolt. It is based on an ongoing ethnographic research started in 2008 in the Pyrenees. After having outlined an atlas of the French back-to-the-land phenomenon, my aim is to analyze its reasons and persistences, 50 years after first people moved to the countryside to live in intentional communities. Some of the areas invested by those people still preserve the original counter-cultural spirit of the 60s-70s, attracting until today « new settlers » trying to live differently form the rest of the society, defend nature and re-create sustainable communities.
Pour une politique du commun du peuple
Authors: Bidet Jacques
Published: February 2020

Néolibéralisme et crise du marxisme. La question écologique. Structure de classe et Système-monde, tabou structurel et tabou systémique. Capitalistes, compétents et classe populaire, duel triangulaire. Régime d'hégémonie. Etat-monde. Appareils d’État mondiaux. Commun du peuple.
CRM Systems as a Tool for Improving Business Efficiency
Authors: Filimonova V.
Published: February 2020

Currently, in order to effectively conduct business and improve the company’s competitiveness, it is necessary to constantly improve the efficiency of management activities, monitor and analyze all stages of business. The use of specialized CRM software will allow companies to improve the efficiency of customer relationship management and quickly solve current problems.
Detective Storyworlds:Longmire,True Detective, andLa trêve
Authors: Dechêne Antoine
Published: February 2020

This paper addresses one question: What makes detective series popular today? In the past, scholars have responded that the genre is mainly focused on plot, to the point of becoming a narrative prototype. This approach explains why detective fiction appears to be more limited in its proliferation across media than other genres such as fantasy or science fiction. If plot is the dominant feature of the genre, and plot somehow works against proliferation, then why are we still producing and consuming so many detective series? Following Marie-Laure Ryan, I wish to argue that a shift from plot to worldbuilding has occurred in detective fiction. This shift follows the evolution of narrative theory which in the last decades had to expand to other disciplines and media. In the same way that narratology embraced the new concept of ‘world,’ popular series have adopted its potential to proliferate, an aptitude that is now truly part of its aesthetics and poetics. I want to describe and understand the increasingly important role played by storyworlds in detective fiction so as to better apprehend how popular series are made in our cultural era of mass media production.
Neuro-Crime Fiction: Detecting Cognitive Difference
Authors: Meeks Spencer
Published: February 2020

This paper seeks to understand how crime fiction connects with the neuroscientific turn occurring in society and culture today. It argues the genre has inherent ties to the science, technology, and biopolitical imperatives underpinning the neuroscientific turn, and is thus uniquely suited to exploring and challenging the ethical considerations arising from it. The paper highlights the symbiotic relationship between crime fiction and neuroscientific models, in which the particularities of the genre are employed by science while science influences the forms of crime fiction. Looking particularly at recent crime novels focussing on types of dementia, it explores how they affect expected generic endings to mount an ideological critique of a strictly medical and material model of identity formation. It does this through a re-working of today's hegemonic model of brain health, dominated by discourses of ‘neuroplasticity,’ looking in particular at how crime fiction can help us to think differently about cognitive differences and diseases.
The Challenges to be a Regulatory Affair Associate:
Day-To-Day Questions on How to Reach Consensus between Manufacturers of Pharmaceutical Products and Government Regulatory Authorities
Authors: Chikobava Elene , Beridze Irma
Published: February 2020

The modern pharmaceutical industry is one of the main branches in the healthcare segment and is considered to be the most highly regulated industries worldwide. The regulation is provided by a specialist, named Regulatory Affairs Manager (syn.: Regulatory Affairs Executive or Regulatory Affairs Associate), involved in authorization process of pharmaceutical products. When person graduates from University with medical, pharmaceutical or even chemical diploma, he/she never thinks about professional career as a Regulatory Affairs Manager, because this specialty is new, about 40 years old.
What is a Regulatory Affairs Associate’s duty? One category-Regulatory Affairs Associate inside the manufacturing office, whose duty is to prepare registration dossier based on the process of artworks and Patient Information Leaflet preparation, prior to completing Common Technical Document (CTD) format dossier; other category (national regulatory affairs Associate)-are those who are ensuring mediation between Manufacturer and Government Regulatory Authorities.
Regardless of differences of each Government requirement for dossier registration, the main task of each Regulatory Affairs Associate is to prepare Dossier for submission which will pass successful registration. For this purpose, the National Regulatory Affairs Associate should ensure that manufacturer/Marketing Authorization Holder (MAH)’s dossier is complete and in line with different documentation requirements, following the national requirements and in case such requirement don’t exist-with the guidelines of the World Health Organization (WHO) and International Council for Harmonization (ICH). On the other hand, National Regulatory Affairs Associate is working with National Regulatory Affairs officers to correct and align deficiencies in documentation in accordance with the National requirements.
Each drug as a living organism (innovative drugs even have birthdays), which is subject to many changes reflected in the registration dossier: whether in its pharmaceutical part (composition, production process, stability etc.,) or pharmacological (therapeutic indications, side effects and others), as a consequence the Regulatory Affairs Manager is constantly involved in registration of an infinite number of Variations. The main goal of Regulatory structures-both governmental and private-is to ensure the safety, quality and efficacy of medicines.
Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice
Authors: Pinterić Marija , Podgorski Iva I. , Hadžija Marijana Popović , Tartaro Bujak Ivana , Dekanić Ana , Bagarić Robert , Farkaš Vladimir , Sobočanec Sandra , Balog Tihomir
Published: February 2020

Metabolic homeostasis is differently regulated in males and females. Little is known about the mitochondrial Sirtuin 3 (Sirt3) protein in the context of sex-related differences in the development of metabolic dysregulation. To test our hypothesis that the role of Sirt3 in response to a high-fat diet (HFD) is sex-related, we measured metabolic, antioxidative, and mitochondrial parameters in the liver of Sirt3 wild-type (WT) and knockout (KO) mice of both sexes fed with a standard or HFD for ten weeks. We found that the combined effect of Sirt3 and an HFD was evident in more parameters in males (lipid content, glucose uptake, pparγ, cyp2e1, cyp4a14, Nrf2, MnSOD activity) than in females (protein damage and mitochondrial respiration), pointing towards a higher reliance of males on the effect of Sirt3 against HFD-induced metabolic dysregulation. The male-specific effects of an HFD also include reduced Sirt3 expression in WT and alleviated lipid accumulation and reduced glucose uptake in KO mice. In females, with a generally higher expression of genes involved in lipid homeostasis, either the HFD or Sirt3 depletion compromised mitochondrial respiration and increased protein oxidative damage. This work presents new insights into sex-related differences in the various physiological parameters with respect to nutritive excess and Sirt3.
Preparation, Cytotoxicity, and In Vitro Bioimaging of Water Soluble and Highly Fluorescent Palladium Nanoclusters
Authors: Thangudu Suresh , Kalluru Poliraju , Vankayala Raviraj
Published: February 2020

Fluorescent probes offer great potential to identify and treat surgical tumors by clinicians. To this end, several molecular probes were examined as in vitro and in vivo bioimaging probes. However, due to their ultra-low extinction coefficients as well as photobleaching problems, conventional molecular probes limit its practical utility. To address the above mentioned challenges, metal nanoclusters (MNCs) can serve as an excellent alternative with many unique features such as higher molar extinction coefficients/light absorbing capabilities, good photostability and appreciable fluorescence quantum yields. Herein, we reported a green synthesis of water soluble palladium nanoclusters (Pd NCs) and characterized them by using various spectroscopic and microscopic characterization techniques. These nanoclusters showed excellent photophysical properties with the characteristic emission peak centered at 500 nm under 420 nm photoexcitation wavelength. In vitro cytotoxicity studies in human cervical cancer cells (HeLa) cells reveal that Pd NCs exhibited good biocompatibility with an IC50 value of >100 µg/mL and also showed excellent co-localization and distribution throughout the cytoplasm region with a significant fraction translocating into cell nucleus. We foresee that Pd NCs will carry huge potential to serve as a new generation bioimaging nanoprobe owing to its smaller size, minimal cytotoxicity, nucleus translocation capability and good cell labelling properties.
Trans-Disciplinary Responses to Climate Change: Lessons from Rice-Based Systems in Asia
Authors: Hellin Jon , Balié Jean , Fisher Eleanor , Kohli Ajay , Connor Melanie , Yadav Sudhir , Kumar Virender , Krupnik Timothy J. , Sander Bjoern Ole , Cobb Joshua , Nelson Katherine , Setiyono Tri , Puskur Ranjitha , Chivenge Pauline , Gummert Martin
Published: February 2020

Climate change will continue to have a largely detrimental impact on the agricultural sector worldwide because of predicted rising temperatures, variable rainfall, and an increase in extreme weather events. Reduced crop yields will lead to higher food prices and increased hardship for low income populations, especially in urban areas. Action on climate change is one of the Sustainable Development Goals (SDG 13) and is linked to the Paris Climate Agreement. The research challenge posed by climate change is so complex that a trans-disciplinary response is required, one that brings together researchers, practitioners, and policy-makers in networks where the lines between “research” and “development” become deliberately blurred. Fostering such networks will require researchers, throughout the world, not only to work across disciplines but also to pursue new South–North and South–South partnerships incorporating policy-makers and practitioners. We use our diverse research experiences to describe the emergence of such networks, such as the Direct Seeded Rice Consortium (DSRC) in South and Southeast Asia, and to identify lessons on how to facilitate and strengthen the development of trans-disciplinary responses to climate change.
Numerical and Experimental Investigations of Asphalt Pavement Behaviour, Taking into Account Interface Bonding Conditions
Authors: Le Minh-Tu , Nguyen Quang-Huy , Nguyen Mai Lan
Published: February 2020

The interface bond between layers plays an important role in the behavior of pavement structure. However, this aspect has not yet been adequately considered in the pavement analysis process due to the lack of advanced characterizations of actual condition. In many pavement design procedures, only completely bonded or unbounded interfaces between the layers are considered. For the purpose of the better evaluation of the asphalt pavement behavior, this work focused on its investigation taking into account the actual interface bonding condition between the asphalt layers. Based on the layered theory developed by Burmister (1943), the actual interaction between pavement layers was taken into account by introducing a horizontal shear reaction modulus which represents the interface bonding condition for a given state. The analytical solution was then implemented in a numerical program before doing forward calculations for sensitivity analysis which highlights the influence of the interface bonding conditions on the structural behaviors of asphalt pavement under a static load. Furthermore, the numerical program was applied through an original experimental case study where falling weight deflectometer (FWD) tests were carried out on two full-scale pavement structures with or without a geogrid at the interface between the asphalt layers. Backcalculations of the FWD measurements allowed determining field condition of the interface bond between the asphalt layers. The obtained values of the interface shear modulus in pavement structure with a geogrid are smaller than the ones in pavement structure without geogrid. Moreover, all of these values representing field performance are at the same order of magnitude as those from dynamic interlayer shear testing.
Effect of Ga and Zr Substitution on the Properties of Dy2Fe17−XZrX and Dy2Fe16Ga1−xZrx (0 ≤ x ≤ 1) Intermetallic Compounds Prepared via Arc Melting Process
Authors: Dahal Jiba Nath , Ali K.S. Syed , Mishra S.R. , Neupane Dipesh
Published: February 2020

The effects of substitution of Zr and Ga on the structural and magnetic properties of Dy2Fe17 intermetallic compound were investigated in this study. The Rietveld analysis confirmed that the crystalline system was a Th2Ni17 structure. Lattice parameters a (Å) and c (Å), unit cell volume (Å3), and bonding distance (Å) were calculated using Rietveld analysis. The unit cell volume of Dy2Fe17−xZrx and Dy2Fe16Ga1−xZrx increased linearly with Zr and Ga substitution. The Curie temperature (Tc) of Dy2Fe17−xZrx and Dy2Fe16Ga1−xZrx was found to be Zr content-dependent. The maximum Curie temperatures were observed at 510 K (x = 0.75 Zr content) for Dy2Fe17−xZrx and 505.1 K (x = 0.5 Zr content) for Dy2Fe16Ga1−xZrx, which are 102 K and 97 K higher than the value found for Dy2Fe17, respectively. The room-temperature Mössbauer analysis showed a decrease in the average hyperfine field and increases in the isomer shift with Zr doping. The overall improvement in Curie temperature with the substitution strategy of Zr–Ga substitution in 2:17 intermetallic compounds could find potential use of these magnetic compounds in high-temperature applications.
New Construction of Strongly Relatively Nonexpansive Sequences by Firmly Nonexpansive-Like Mappings
Authors: Işık Hüseyin , Haddadi Mohammad Reza , Parvaneh Vahid , Park Choonkil , Kornokar Somayeh
Published: February 2020

In recent works, many authors generated strongly relatively nonexpansive sequences of mappings by the sequences of firmly nonexpansive-like mappings. In this paper, we introduce a new method for construction of strongly relatively nonexpansive sequences from firmly nonexpansive-like mappings.
On the Connection between Spherical Laplace Transform and Non-Euclidean Fourier Analysis
Authors: De Micheli Enrico
Published: February 2020

We prove that, if the coefficients of a Fourier–Legendre expansion satisfy a suitable Hausdorff-type condition, then the series converges to a function which admits a holomorphic extension to a cut-plane. Next, we introduce a Laplace-type transform (the so-called Spherical Laplace Transform) of the jump function across the cut. The main result of this paper is to establish the connection between the Spherical Laplace Transform and the Non-Euclidean Fourier Transform in the sense of Helgason. In this way, we find a connection between the unitary representation of SO ( 3 ) and the principal series of the unitary representation of SU ( 1 , 1 ) .
The Relations between Residuated Frames and Residuated Connections
Authors: Kim Yong Chan , Oh Ju-Mok
Published: February 2020

We introduce the notion of (dual) residuated frames as a viewpoint of relational semantics for a fuzzy logic. We investigate the relations between (dual) residuated frames and (dual) residuated connections as a topological viewpoint of fuzzy rough sets in a complete residuated lattice. As a result, we show that the Alexandrov topology induced by fuzzy posets is a fuzzy complete lattice with residuated connections. From this result, we obtain fuzzy rough sets on the Alexandrov topology. Moreover, as a generalization of the Dedekind–MacNeille completion, we introduce R-R (resp. D R - D R ) embedding maps and R-R (resp. D R - D R ) frame embedding maps.
Discovery of Two Brominated Oxindole Alkaloids as Staphylococcal DNA Gyrase and Pyruvate Kinase Inhibitors via Inverse Virtual Screening
Authors: Sayed Ahmed M. , Alhadrami Hani A. , El-Hawary Seham S. , Mohammed Rabab , Hassan Hossam M. , Rateb Mostafa E. , Abdelmohsen Usama Ramadan , Bakeer Walid
Published: February 2020

In the present study, a small marine-derived natural products library was assessed for antibacterial potential. Among 36 isolated compounds, a number of bis-indole derivatives exhibited growth-inhibitory activity towards Gram-positive strains (Bacillus subtilis and multidrug-resistant Staphylococcus aureus). 5- and 6-trisindoline (5-Tris and 6-Tris) were the most active derivatives (minimum inhibitory concentration, MIC, 4–8 µM) that were subsequently selected for anti-biofilm activity evaluation. Only 5-Tris was able to inhibit the staphylococcal biofilm formation starting at a 5 µM concentration. In order to investigate their possible molecular targets, both natural products were subjected to in silico inverse virtual screening. Among 20 target proteins, DNA gyrase and pyruvate kinase were the most likely to be involved in the observed antibacterial and anti-biofilm activities of both selected natural products. The in vitro validation and in silico binding mode studies revealed that 5-Tris could act as a dual enzyme inhibitor (IC50 11.4 ± 0.03 and 6.6 ± 0.05 µM, respectively), while 6-Tris was a low micromolar gyrase-B inhibitor (IC50 2.1 ± 0.08 µM), indicating that the bromine position plays a crucial role in the determination of the antibacterial lead compound inhibitory activity.
Safety Aspects of Genetically Modified Lactic Acid Bacteria
Authors: Plavec Tina Vida , Berlec Aleš
Published: February 2020

Lactic acid bacteria (LAB) have a long history of use in the food industry. Some species are part of the normal human microbiota and have beneficial properties for human health. Their long-standing use and considerable biotechnological potential have led to the development of various systems for their engineering. Together with novel approaches such as CRISPR-Cas, the established systems for engineering now allow significant improvements to LAB strains. Nevertheless, genetically modified LAB (GM-LAB) still encounter disapproval and are under extensive regulatory requirements. This review presents data on the prospects for LAB to obtain ‘generally recognized as safe’ (GRAS) status. Genetic modification of LAB is discussed, together with problems that can arise from their engineering, including their dissemination into the environment and the spread of antibiotic resistance markers. Possible solutions that would allow the use of GM-LAB are described, such as biocontainment, alternative selection markers, and use of homologous DNA. The use of GM-LAB as cell factories in closed systems that prevent their environmental release is the least problematic aspect, and this is also discussed.
Graphene Quantum Dots with High Yield and High Quality Synthesized from Low Cost Precursor of Aphanitic Graphite
Authors: Shen Shuling , Wang Junjie , Wu Zhujun , Du Zheng , Tang Zhihong , Yang Junhe
Published: February 2020

It is difficult to keep the balance of high quality and high yield for graphene quantum dots (GQDs). Because the quality is uncontrollable during cutting large 2D nanosheets to small 0D nanodots by top-down methods and the yield is low for GQDs with high quality obtained from bottom-up strategy. Here, aphanitic graphite (AG), a low-cost graphite contains a large amount of small graphite nanocrystals with size of about 10 nm is used as the precursor of graphene oxide quantum dots (GO-QDs) for the first time. GO-QDs with high yield and high quality were successfully obtained directly by liquid phase exfoliating AG without high strength cutting. The yield of these GO-QDs can reach up to 40 wt. %, much higher than that obtained from flake graphite (FG) precursor (less than 10 wt. %). The size of GO-QDs can be controlled in 2–10 nm. The average thickness of GO-QDs is about 3 nm, less than 3 layer of graphene sheet. Graphene quantum dots (GQDs) with different surface properties can be easily obtained by simple hydrothermal treatment of GO-QDs, which can be used as highly efficient fluorescent probe. Developing AG as precursor for GQDs offers a way to produce GQDs in a low-cost, highly effective and scalable manner.
A Survey of the Individual Claim Size and Other Risk Factors Using Credibility Bonus-Malus Premiums
Authors: Gómez-Déniz Emilio , Calderín-Ojeda Enrique
Published: February 2020

In this paper, a flexible count regression model based on a bivariate compound Poisson distribution is introduced in order to distinguish between different types of claims according to the claim size. Furthermore, it allows us to analyse the factors that affect the number of claims above and below a given claim size threshold in an automobile insurance portfolio. Relevant properties of this model are given. Next, a mixed regression model is derived to compute credibility bonus-malus premiums based on the individual claim size and other risk factors such as gender, type of vehicle, driving area, or age of the vehicle. Results are illustrated by using a well-known automobile insurance portfolio dataset.
Suggestions for Chinese University Freshmen Based on Adaptability Analysis and Sustainable Development Education
Authors: Chen Huaruo , Ling Ling , Ma Yonghui , Wen Ya , Gao Xiyuan , Gu Xueying
Published: February 2020

Based on the theory of sustainable development education, this paper tested the adaptability of contemporary university freshmen. Using the compilation and revision of China’s College Student Adjustment Scale (CCSAS). This paper examines five dimensions: personal emotional adaptability, learning adaptability, interpersonal adaptability, university identity, and living adaptability. Using a sample of 640 freshmen (from more than 30 universities) and considering the three dimensions of gender, major, and origin, the paper reaches the following conclusions. Generally, the adaptability of freshmen was positive and their adaptation is good; from the perspective of gender, males and females are different in physiology and psychology; from the perspective of major, there are no significant differences; from the perspective of students’ origin, there was no significant difference in general, but there were significant differences in personal emotions and university identity. Based on the above results, this paper emphasizes that to achieve the goal of sustainable development education, universities should begin to pay attention to the adaptability of students as soon as they enter the university. In addition to paying attention to the quality of teaching and learning, universities should also pay attention to the individual differences among students and the related factors that hinder their sustainable development. To ensure that students can meet the challenges of society in the future, the university should cultivate students’ awareness of sustainable development and their ability to participate in and develop sustainable practices.
Decision-Making of Green Space Utilization and Protection in Urban Fringe Based on Biodiversity Trade-Off
Authors: Liu Haijiao , Ma Yonghong , Liu Qing , Song Yan
Published: February 2020

Urbanization leads to the continuous expansion of urban built-up areas and the erosion of green space in urban fringe areas, leading to the continuous decline of biodiversity. Urban planners and managers need corresponding decision support tools to coordinate the contradiction between the utilization and protection of green space, ensure the maintenance capacity of biodiversity in green space, and realize the sustainable development of regional economy, society and ecology. Therefore, based on the Hellwig Method, this study designed a decision-making method of green space utilization and protection in urban fringe areas and applied the method to the decision simulation of single or multiple green space utilization and protection modes. In the decision simulation of a green space utilization mode, we evaluated the Hk values of one or several green space sample units, respectively. The smaller the Hk value, the smaller the influence of the green space unit on the biodiversity maintenance function of the whole green space in the region, so the green space unit can be selected first when making green space utilization planning decisions in the urban fringe. In the decision simulation of green space protection mode, the higher the Hk value of single green space sample unit combination or multiple green space sample unit combination, the greater the influence of the green space unit in the combination on the maintenance function of the overall green space biodiversity in the region. Then, when planning the green space protection in the urban fringe, the combination of such green space sample units should be given priority as the key protection and control objects. As a decision support tool for optimal scheme of green space utilization and protection in urban fringe areas, the method is practical, instructive, reasonable, operable, flexible, and universal.
Sustainability and Collaboration: Crossdisciplinary and Cross-Sector Horizons
Authors: Klein Julie Thompson
Published: February 2020

The title of this article signals increasing collaboration across boundaries aimed at understanding and solving complex scientific and societal problems. The article is a reflective analysis of five intersecting keywords in discussions of sustainability and boundary crossing. This genre of discourse studies interprets language use, drawing in this case on a representative sample of authoritative definitions, case studies, and state-of-the-art accounts. The Introduction situates the discussion around the increasing number and size of teams as well as research across both academic disciplines and other sectors, followed by the five keywords that structure the overall argument. Section 2 examines the first of the five keywords, defining interdisciplinarity by marking its alignment with integration, confluence, interdependence, interaction, and balance. Section 3 considers the second keyword—transdisciplinarity—by tracing evolution of a problem-focused connotation, links to sustainability, inclusion of stakeholders, the imperative of critique, and transdisciplinary action research. Section 4 brings together insights on inter- and trans-disciplinarity in a composite “crossdisciplinary” alignment with collaboration, factoring in the nature of teamwork, public engagement, and translation. Section 5 then turns to learning, noting the difference between education and training then emphasizing transformative capacity, double- and triple-loop learning, reflexivity, and a transdisciplinary orientation. Section 6 takes up the final keyword—knowledge—by calling attention to inclusion, indigenous and local perspectives, nomothetic versus idiographic perspectives, the question of fit, and the nature of crossdisciplinary knowledge. The article concludes by identifying future research needs.
Correction: Zika Virus-Derived E-DIII Protein Displayed on Immunologically Optimized VLPs Induces Neutralizing Antibodies without Causing Enhancement of Dengue Virus Infection. Vaccines 2019, 7, 72
Authors: Cabral-Miranda Gustavo , Lim Stephanie M. , Mohsen Mona O. , Pobelov Ilya V. , Roesti Elisa S. , Heath Matthew D. , Skinner Murray A. , Kramer Matthias F. , Martina Byron E. E. , Bachmann Martin F.
Published: February 2020

The authors wish to make the following correction to their paper [...]
Tank Volume Control Using LabVIEW and Arduino UNO
Authors: A Ardilessi
Published: February 2020

Abstract - Rapid technological developments in contemporary times also affected the development of the toolsin an industry.Equipment in an industry that was once driven manually by humans are now beginning to be controlled automatically. One of the automatic controller system that is widely used in an industrial controller system is proportional integral derivative (PID). PID controller consists of three kinds of methods that the controller proportional controller, the integral controller, and derivative controller. Controlling the height levels of the system is done through LabView 2013. Arduino UNO board is used to process the data on the flow sensor and height sensor.Data obtained from the height sensor and flow sensor is used to set the input and output water tank so that the water level in accordance with the desired height. From the test results, using Ti as an input parameter in the integral action zigler – Nichols method. Condition stable and constant oscillation at the output level elevation will be obtained, when the conditions given parameter value Ti is getting bigger and parameter values Kp given increasingly smaller. By using the parameters obtained from the calculation using the method zigler – Nichols, obtained results faster output stable when using a PI controller. Keyword : Controller, Proportional Integral Derivative, Ziegler-Nichols, LabView
Room Temperature Controller uses the PID
Authors: Firdaus Ramadan
Published: February 2020

Abstract - Today's automatic control system provides many benefits for humans. Apart from being able to increase work time, automatic control can also reduce human errors and increase work effectiveness. One application of automatic control is controlling temperature with the aim of obtaining the desired temperature in a relatively short time and can maintain the temperature in a stable condition. The temperature control system can be applied using the Arduino and LabVIEW boards. In this temperature control system one LM35 temperature sensor is used. The temperature sensor is placed in a position that is adjusted to the inside of the plant to find the temperature transfer that occurs in the plant. Data from the sensor then goes to the Arduino board, which in this control system uses data as an acquisition. To maintain the temperature inside the factory, use a ventilation fan to lower the temperature if the temperature inside the plant exceeds the set point. To control the fan used this controls the PID which is implemented through LabVIEW. In addition to implementing the PID control, LabView is used as an interface to find out the actual temperature of the plant RPM speed of the fan used and filling in the PID parameters. In the PID approval three parameters can be obtained with Ziegler-Nichols penalties. The results of the study show that the plant response is continuous oscillation and can be overcome by using Ziegler-Nichols continuous oscillation punishment. By using LabVIEW PID and punishment parameters using the Ziegler-Nichols method, for a set point temperature of 28oC the plant response is (28 ± 0.5) oC. In other words controlling temperature using the PID control and the Ziegler-Nichols method have errors below 2% indicating that the temperature control system is feasible to use. Keyword : Temperature, PID Control, LabVIEW, Arduino board, Ziegler-Nichols.
Doença de Parkinson e reabilitação vestibular
Authors: Botelho Isabela Silva , Lopes Lízia Laiz Costa Dias , Sousa Maria da Glória Canto de
Published: February 2020

Introdução. Estudos realizados obtiveram achados que evidenciam uma grande incidência de respostas vestibulares na população portadora da doença de Parkinson (DP) e que, portanto, a reabilitação vestibular (RV) pode trazer benefícios para esses pacientes, melhorando a sintomatologia e o prognóstico clínico. Objetivo. Demonstrar os efeitos de um programa de RV em um paciente portador de doença de Parkinson. Método. Trata-se de um estudo de caso. O paciente submeteu-se a um programa de RV a fim de obter a diminuição ou remissão do sintoma tontura. Foi utilizado o Dizziness Handicap Inventory (DHI) para comparação dos resultados pré e pós-programa. Resultados. As subescalas física, emocional e funcional do DHI obtiveram os seguintes escores pré-programa: subescalas física 12 pontos, funcional 4 pontos e emocional 8 pontos, totalizando 24 pontos e pós-programa, escore de zero ponto nas três subescalas no retorno do período das férias. Conclusão. De acordo com o estudo foi possível constatar que o programa de reabilitação vestibular, ora proposto, trouxe benefícios para o paciente que evoluiu sem queixas de tontura e com redução importante dos escores em relação ao escore total geral no início do programa.
Historia de vida de una colección. El caso del museo arqueológico de Chasicó, Partido de Tornquist (Provincia de Buenos Aires)
Authors: Oliva Camila
Published: February 2020

Algunas de las colecciones arqueológicas de importantes museos de la República Argentina han sido investigadas extensamente por la comunidad científica, principalmente en relación a su valoración material como evidencia de la ocupación pretérita de grupos humanos. Sin embargo, los estudios de este tipo de colecciones en los museos locales de la Provincia de Buenos Aires han sido escasamente desarrollados. Las colecciones pueden ser abordadas como archivos históricos, dado que contienen información de la contextualización historiográfica del momento de su conformación; en este sentido, no es posible considerar a la colección sin la figura del sujeto que la conformó y su capacidad de agencia (i.e. coleccionistas, aficionados, arqueólogos, historiadores, entre otros). El objetivo principal de este artículo es analizar los relatos que dan cuenta del proceso de creación de las colecciones del Museo Arqueológico de Chasicó, ubicado en la Estancia Don Natalio, partido de Tornquist, provincia de Buenos Aires. Cabe destacar que se trata de una institución declarada Sitio Histórico Municipal desde el año 2006, y cuenta con un importante número de piezas paleontológicas y arqueológicas prehispánicas e históricas correspondientes a los grupos humanos que habitaron el sector sur del Área Ecotonal Húmedo Seca Pampeana. Bajo este marco, se propone abordar metodológicamente el registro de la memoria oral de la Licenciada Nora Cinquini, tutora de las colecciones que alberga el museo. De esta manera, se entiende a la memoria como una forma de expresión de identidad, la cual permite considerar a los procesos de construcción identitarios de una comunidad y su vínculo con el pasado. El presente trabajo busca indagar la utilidad, el valor académico y los aportes generados por los estudios historiográficos -en cuanto al origen de las colecciones arqueológicas museísticas- para la comprensión de procesos identitarios que emergen de este tipo de institución.