bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrospun scaffolds for heart valve tissue engineering
Authors: Gürbüz Betül , Balikci Elif , Baran Erkan Türker
Published: February 2025

A potential solution for prosthetic heart valves is tissue-engineered heart valves. Tissue-engineered heart valves (TEHVs) are designed to replicate the complex properties found in natural tissues, such as stiffness, anisotropy, and composition and organization of cells and extracellular matrix (ECM). Electrospinning is regarded as a highly versatile and innovative approach for fabricating numerous fibrous designs. In this review, we discuss recent developments in electrospun heart valve scaffolds, including scaffold materials, cell types, and electrospinning setups used to prepare aligned nanofibers. Despite the fact that natural biomaterials provided excellent biocompatibility, nanofibers from synthetic materials provided the required mechanical compatibility. Accordingly, most studies highlighted the benefits of designing composite heart valves using biological and synthetic polymers. Various strategies, such as the application of motorized mandrel and micropatterned collector in electrospinning were effective in controlling nanofiber alignment. Studies also showed that aligned nanofiber’s mechanical strength and anisotropic structure promote cell proliferation, and differentiation, and promote attachment. Numerous studies have reported that multiple cell sources are suitable for producing heart valves. Successful results were obtained with human umbilical vein endothelial cells (HUVECs), since they provide a convenient cell source for cellularization of valve leaflets. A higher conductivity of scaffolds was achieved by using biomaterials that conduct electricity, such as polyaniline, polypyrrole, and carbon nanotubes, which resulted in better differentiation of precursor cells to cardiomyocytes and higher cell beating rates. In light of these attributes, nanofibrous scaffolds produced through electrospinning are expected to offer numerous advantages for tissue engineering and medical applications in the near future. However, multiple challenges were identified as cell infiltration and 2D nature of nanofiber mats necessitate further engineering approaches in electrospinning procedure leaflet production.
Mitochondrial dysfunction in PBMC: a potential sensor for metabolic dysfunction-associated steatotic liver disease and therapeutic insight for NAD+-increasing strategies
Authors: Niño-Narvión Julia , Rossell Joana , Rojo-López Marina Idalia , Moreira Estefanía , Mateus Eder , Ruiz-Alcaraz Antonio José , Ramos-Molina Bruno , Martínez-Rojo Elizabeth , Martinez Laurent O. , Galán Maria , Julve Josep
Published: February 2025

The epidemic of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly growing worldwide. Thus, there is an urgent need for novel, non-invasive, and reliable biomarkers to replace liver biopsy for the diagnosis and prognosis of MASLD. Circulating peripheral blood mononuclear cells (PBMCs) are highly responsive to various stimuli and physiological changes. Beyond their immunomodulatory role, PBMC may act as metabolic sensors in several cardiometabolic disorders, including MASLD, with their metabolic programs shifting accordingly. Recent evidence suggests a link between impaired mitochondrial bioenergetics in PBMC and MASLD. Additionally, impaired mitochondrial respiration is intricately linked to the intracellular depletion of the oxidized form of nicotinamide adenine dinucleotide (NAD+) in various cell types. Accumulating preclinical and clinical data show that NAD+-increasing strategies may protect against MASLD by restoring intracellular NAD+ pools and improving mitochondrial performance. This review will focus on [i] the relevance of mitochondrial dysfunction, including impaired bioenergetics, in PBMC as a marker for the diagnosis and prognosis of MASLD, and [ii] the potential benefits of NAD+ precursors in MAFLD and their relationship with improved mitochondrial respiration in blood immune cells.
A fenntarthatósági feltételek érvényesítésének hatékony elősegítése a kórházakat érintő közbeszerzésekben (Közbeszerzések zöldítése az egészségügyben)
Authors: Varga Luca
Published: February 2025

A tanulmány célja olyan - az egészségügyben lefolytatott közbeszerzési eljárásokban alkalmazott - fenntarthatósági feltételek alkalmazásának bemutatása a nemzetközi gyakorlatból, amelyeket a hazai egészségügyi közbeszerzések és beszerzések zöldítése érdekében implementálni ajánlott. A fenntarthatósági téma az uniós zöld törekvések miatt mindig középpontban lesz, de a tanulmány aktualitását a COVID-19 járvány életünkre és környezetünkre gyakorolt hatása adta, így az egészségügyi közbeszerzések uniós és hazai jogszabályi bemutatása mellett, a világjárvány okozta új körülményekhez való alkalmazkodás által “életbe lépett” új változásokat is igyekszem bemutatni, részletezve az egészségügyi intézmények fenntartói irányításában bekövetkezett változásokat.
Qualitative and physical-chemical indicators of chitosan samples and their comparative characteristics with imported analogues
Authors:   Yanka Kupala State University of Grodno, Pavlova O. V. , Anufrik S. S. ,   Yanka Kupala State University of Grodno, Eisymont E. I. ,   Yanka Kupala State University of Grodno, Trusova M. M. ,   Yanka Kupala State University of Grodno
Published: February 2025

The work is devoted to the study of the qualitative and physicochemical indicators of chitosan obtained by acid-base hydrolysis and enzymatic hydrolysis, and their comparative characteristics with an imported analogue. The introduction identifies the problem in the field of obtaining and using technological auxiliary materials in the beverage industry. The scientific task is to compare the experimentally obtained technological auxiliary materials (chitosan with a deacetylation degree of 62%, insoluble in 1% solutions of organic acids, chitosan with a deacetylation degree of 98%, soluble in 1% solutions of organic acids and imported chitosan (China) in order to obtain import substitution. Classical methods of physicochemical analysis were used as materials and methods to determine the concentration of chemical elements in chitosan samples, a statistical analysis method. It was found that a chitosan sample with a deacetylation degree of 98% has a structure similar to the structure of chitosan produced in China, chitosan with a deacetylation degree of 62% has an amorphous-crystalline structure. In conclusion, a conclusion was made about the compliance of the quality of the obtained samples with the reference chitosan, about the prospects for using chitosan in technological processes taking into account its structural features.
Widespread Prevalence of Diphtheria in Nigeria, Africa: Identification, Pathogenic Impact, and Control of Corynebacterium diphtheriae
Authors: Eruchalu .I. Augustine
Published: February 2025

Corynebacterium diphtheriae is a Gram-positive bacterium responsible for diphtheria, a severe and potentially life-threatening disease. With a mortality rate of up to 20%, diphtheria remains a major public health concern, particularly in regions with low vaccination coverage, such as parts of Africa.
This paper provides a comprehensive overview of the pathogenesis, epidemiology, and laboratory identification of C. diphtheriae, along with its diagnosis and treatment options. Additionally, we will explore the history of diphtheria vaccination, current immunization strategies, and ongoing efforts to control this preventable disease. By emphasizing the importance of sustained public health initiatives and high vaccination coverage, we aim to underscore the urgency of preventing the resurgence of this deadly infection.
Modern approaches to the combat use of combined aircraft units in tactical groups
Authors:   Head of the Department of Tactics and Special Disciplines, Military Aviation Institute of the Republic of Uzbekistan, Jumabaevich Rakhimov Murod , Saribayevich Parmonov Baxtiyor ,   Senior Lecturer at the Department of Tactics and Special Disciplines of the Military aviation institute of the Republic of Uzbekistan
Published: February 2025

This article analyzes the views of foreign military experts on the procedure for using helicopter units in modern armed conflicts and the development of tactics for helicopter aviation operations, both independently and in conjunction with other types of aviation. Special attention is given to the nature of helicopter unit actions in both offensive and defensive operations, as well as the tactics for helicopter aviation operations, whether conducted independently or as part of joint operations within mixed UAV-aircraft-helicopter groups. In such groups, the presence of helicopters and unmanned reconnaissance systems with real-time information transmission has become mandatory.
The effect of rice flour addition on pasta quality: a case study from the republic of uzbekistan
Authors:   Assistant Teacher, Yangier Branch of the Tashkent Chemical-Technological Institute, Yangiyer, Uzbekistan, Raxmatov F.E. , O‘ktamov Sh.B. ,   Assistant Teacher, Yangier Branch of the Tashkent Chemical-Technological Institute, Yangiyer, Uzbekistan, Obloberdiyev S.N. ,   Assistant Teacher, Yangier Branch of the Tashkent Chemical-Technological Institute, Yangiyer, Uzbekistan, Abdukarimova M.B. ,   Student, Yangier Branch of the Tashkent Chemical-Technological Institute, Yangiyer, Uzbekistan, Raxmonberdiyeva S.B. ,   Student, Yangier Branch of the Tashkent Chemical-Technological Institute, Yangiyer, Uzbekistan
Published: February 2025

The study investigates the impact of rice flour addition to wheat flour in pasta production, focusing on quality attributes such as texture, cooking properties, and sensory evaluation. The research explores the physicochemical changes occurring due to different rice flour concentrations (10%, 20%, and 30%) and their effect on gluten structure, firmness, and cooking stability. Laboratory analyses, including protein content, moisture retention, and elasticity tests, were conducted to evaluate the influence of rice flour substitution. The results indicate that a moderate incorporation of rice flour (10–20%) maintains acceptable pasta quality while improving digestibility and reducing gluten-related concerns. However, excessive rice flour content (30%) negatively impacts structural integrity and sensory appeal. This study provides valuable insights into alternative flour utilization in pasta production, contributing to the development of gluten-modified and functional food products.
The concept of ‘‘health’’ in russian and uzbek languages: linguocultural perspective
Authors:   (DSc), Head of the Department of Uzbek and Foreign Languages, Tashkent Medical Academy, Uzbekistan, Mirzatullayevna Abdullayeva Rozanna
Published: February 2025

the linguistic essence of the concept of ‘‘health‘‘ as a multidimensional phenomenon encompassing physiological, sociocultural, and axiological aspects is examined in this paper. It analyzes the structure of a concept, its lexical-semantic field, phraseology, and metaphorical models that highlight the pivotal role of health in various cultural worldviews. The study emphasizes that in modern society, the concept of ‘‘health’’ is continuously expanding with new meanings and practices related to personal development and environmental awareness.
Typology of borrowings in linguistics
Authors:   Researcher of Kokand state pedagogical institute, Uzbekistan, Sharipov Ziyod
Published: February 2025

This study investigates the typology of borrowings in linguistics, focusing on the processes, types, and adaptation mechanisms of borrowed words in various languages. Borrowings, also known as loanwords, occur when one language adopts words from another due to contact and cultural exchange. The research classifies borrowings into types such as lexical, phonological, morphological, and semantic borrowings. Special attention is given to the comparative typology of English and Uzbek borrowings, highlighting their phonetic and semantic changes. The findings contribute to understanding the dynamics of linguistic change and cross-linguistic influence.
The theoretical foundations of cognitive linguistics, and the relationship between language and mind
Authors:   Senior teacher of the department of integrated course of English language 3, Uzbekistan, Norboyevich Umarov Bobur
Published: February 2025

Cognitive linguistics is a branch of linguistics that studies the interrelationship between language and the human mind. It examines the meanings and concepts embedded in language in connection with human cognition, perceptual processes, and mental mechanisms. Language and thought are interconnected—language is not merely a means of communication but also reflects how humans perceive and interpret the world. This article explores the theoretical foundations of cognitive linguistics, as well as the relationship between language and the mind, and analyzes relevant data to provide a comprehensive understanding of this field.
The Role of Latin in the Pedagogical Process: Connection with Medical Disciplines
Authors:   Senior Lecturer, Kimyo International University in Tashkent, Uzbekistan, Abdunabiyevna Ibragimova Shoira
Published: February 2025

The article is devoted to the study of the role of Latin in the pedagogical process, with an emphasis on its connection with medical disciplines. Latin, being the basis of scientific and medical terminology, plays an important role in the training of specialists in the field of medicine and pedagogy. The article discusses the main advantages of its study for students studying in the field of humanities and medical sciences, and analyzes the methods of teaching Latin in educational institutions. Particular attention is paid to how Latin contributes to the development of critical thinking and an in-depth understanding of specialized terms used in medicine and other scientific disciplines. In conclusion, the importance of preserving Latin as part of the modern educational process and its significance for future specialists is emphasized.
Classical and modern music theory: comparison and interaction
Authors:   Senior lecturer, Urgench State Pedagogical Institute, Uzbekistan, Narimanovna Allayarova Nargiza
Published: February 2025

The topic of comparison and interaction between classical and modern music theory is aimed at studying important aspects of musical development. This article discusses the main principles of classical music theory, how they have influenced modern music, and how modern musical styles reinterpret classical traditions. The study analyzes factors such as historical context, musical structures, harmonic and rhythmic aspects, as well as performance styles. The article also provides examples of how modern composers use and reinterpret the classical heritage. As a result, the continuity and renewal processes between classical and modern music theory are emphasized.
Electrochemical synthesis of cyclic biaryl λ3-bromanes from 2,2’-dibromobiphenyls
Authors: Savkins Andrejs , Sokolovs Igors
Published: February 2025

The remarkable nucleofugality of bromoarenes in diarylbromonium species renders them particularly suitable for the generation of arynes for subsequent use in a wide range of synthetic applications. The common approach to generate cyclic biaryl λ3-bromanes is based on thermal decomposition of hazardous diazonium salts. Herein, we disclose a mild and straightforward approach to diarylbromonium species by direct anodic oxidation of 2,2'-dibromo-1,1'-biphenyl. The electrochemical method provides access to a range of symmetrically and non-symmetrically substituted cyclic biaryl λ3-bromanes in moderate yields.
IMPLEMENTATION OF MIND MAPPING LEARNING MODEL TO IMPROVE STUDENTS' CREATIVITY IN SCIENCE LESSONS IN GRADE III OF SD GMIT KUANINO 1 KUPANG CITY
Authors: Ndoluanak Dira , Tanggur Femberianus S. , Benu Asti Y. , Nitte Yulsi M.
Published: February 2025

The mind mapping learning model is a visualization technique that helps students organize information, plan ideas, and connect concepts more effectively. By using mind mapping, students can be more active in the learning process, so that they can improve their absorption and understanding of the material being taught. By actively involving students in learning, it is hoped that they can develop creative and innovative thinking skills, and gain a deeper understanding of science and natural sciences material. This study aims to examine the implementation of the mind mapping learning model in improving student creativity in science and natural sciences learning in grade 3 of GMIT Kuanino 1 Elementary School, Kupang City. The method used in this study is a type of qualitative research with a descriptive method. The data collection instruments in this study were observation sheets, interview guidelines, documentation studies. And the data analysis techniques used in this study were Data Collection, Data Reduction, Data Verification, and Data Presentation. The results of the study showed thatThe implementation of this method significantly increases students' creativity and engagement in the learning process. Students show high enthusiasm and active involvement during the mind mapping process, which not only makes them understand the subject matter better, but also encourages them to dare to express ideas through image visualization and the use of color.
INFLUENCE OF DEEP MARGIN ELEVATION ON STRESSES AND DEFORMATIONS OF CLASS II CAVITY MOLARS: A THREE-DIMENSIONAL FINITE ELEMENTS ANALYSIS
Authors: Sato Victória de Andrade Dallara , Carvalho Marco Aurélio de , Carvalho Priscilla Cardoso Lazari
Published: February 2025

The restoration of teeth with large cavities is common and represents a challenge in dentistry, especially those that present deep proximal cavities. The Deep Margin Elevation (DME) technique is a method used to restore teeth with subgingival proximal cavities and to relocate the subgingival cervical margins to an equigingival or supragingival position. In this study, the influence of deep margin elevation on proximal boxes of mesio-occluso-distal (MOD) cavities was evaluated using the Finite Element Method (FEM), in comparison with clinical crown lengthening in the biomechanics of lower molars. The study conducted was a laboratory-based computational simulation. Three models were obtained: H-Healthy Tooth; EMP-Deep Margin Elevation; AC-Clinical Crown Lengthening. The response variables were: maximum principal stress, von Mises stress, and maximum principal displacement for all the involved structures. The 3D reconstruction of tomographic images of a lower first molar was carried out with the help of the InVesalius software, exported to the SolidWorks CAD software; to the Ansys Workbench software, and the analysis was performed using FEM. Axial loading was applied at 3 contact points on the occlusal surface, simulating tripod contact between arches in the mandibular intercuspation position with a magnitude of 400N. For the enamel of model H, the highest stress values were observed, followed by the EMP and AC models. In the Deep Margin Elevation model, the values were similar to those found in the healthy tooth. The increase in clinical crown led to higher stress values for the bone tissue, dentin, and inlay restoration.
UNDERSTAND AND BELONG: SCHOOLS AS SPACES FOR THE INCLUSION OF CHILDREN WITH AUTISM
Authors: Silva Fernanda Galdino da , Peixoto Josana Castro
Published: February 2025

Autism is considered a complex syndrome that involves developmental deviations from the early years of life in the areas of social interaction, communication, and behavior, with multiple causes and manifestations that encompass a wide variability of symptoms and responses to interventions. It was initially described by the Austrian psychiatrist LeoKanner in 1943, based on the cases of 11 children he was observing who exhibited impairments in three areas: social relationships, communication/language, and behavior. The author stated that individuals with autism had an innate inability to emotionally relate to other people, which would depend on a biological aspect. Due to the increasing number of cases of children with Autism Spectrum Disorder (ASD) and their relationship with the process of inclusion and belonging, the objective of this research was to describe and update the methodological bibliographic field in the relationship between ASD and topophilia. Understanding the theoretical-methodological concepts is of fundamental importance to subsequently evaluate the participation of the actors in theschool unit to promote the school inclusion of autistic children, which occurs through the effective participation of the parties.
COMPARISON OF THE EFFECT OF GAMETHERAPY VERSUS CINESIOTHERAPY ON FUNCTION, RANGE OF MOTION OF UPPER LIMBS, AND BRAIN ACTIVITY IN CHILDREN WITH DOWN SYNDROME: A CROSSOVER, PLACEBO-CONTROLLED, DOUBLE-BLIND CLINICAL TRIAL.
Authors: Cordeiro Lorraine Barbosa , Lopes Jamile Benite Palma , Ribeiro Pedro Augusto Silva , Freitas Victoria Renata Evangelista de , Silva Giovana Lima , Souza Eduardo Ferreira de , Duarte Natália de Almeida Carvalho , Kahani Danial , Oliveira Claudia Santos
Published: February 2025

Down Syndrome (DS) is a genetic condition characterized by a chromosomal abnormality1,2. There is a variability of deficits in the learning process and in the development of motor skills with a delay in the acquisition of basic motor milestones, impacting3,5 selective motor control, compromising motor acquisitions and the functional independence of the individual4.
In the field of assessments, there is currently the use of human movement analysis of upper limbs (UL)6., the kinematics of upper limb movement in children has already been addressed in several studies6, 7 with excellent results, the association of brain activity assessment with the use of electroencephalogram can provide a comprehensive evaluation of motor adaptation through the simultaneous study of biomechanical and electroencephalographic evidence, being able to clarify how the motor and brain activity of individuals with neurological diagnoses differs from normal movement patterns during the preparation, execution, and post-execution phases of a task8.
Given all the deficits mentioned in the field of rehabilitation, we have classical kinesiotherapy applied to the improvement of motor function in individuals with DS. we have classical kinesiotherapy with kinesiotherapy that generates beneficial9 effects, and currently, we have the use of gametherapy with the purpose of promoting movement repetition through functional and motor training10.
Thus, the objective of the present study is to conduct a comparative analysis between the effects of ten sessions of upper limb gametherapy training and kinesiotherapy on the functionality, movement pattern (spatio-temporal parameters, kinematics), and brain and muscle activity of children with Down syndrome.
The Effect of Environmental Performance, Environmental Costs and Environmentally Friendly Products on Financial Performance
Authors: AMANDA Febyanti Dwi , WIYONO Slamet , ARYATI Titik
Published: February 2025

This research aims to find out whether environmental performance, environmental cost and eco-friendly products influence the financial performance of manufacturing companies on the Indonesia Stock Exchange. This type of company was chosen because the company has a high level of sensitivity which is of concern to investors due to the large amount of energy expended for its operational activities. The population used is cement, chemical and mining industry companies listed on the Indonesia Stock Exchange in 2021-2023. Sample selection was used through a purposive sampling method, during the 2021-2023 observation period and was not delisted during the research period, resulting in a total sample of 120 samples. Based on the testing of 120 samples, tests were then carried out including descriptive statistics, classical assumption tests and research hypothesis tests. The results of the hypothesis test are that environmental performance has a positive effect on the company's financial performance, environmental costs have a positive effect on the company's financial performance, and environmentally friendly products have a positive effect on the company's financial performance.
Comparative Assessment of Microbial Community in Compost Samples
Authors: Kiani Noor Ul Huda , Farooq Saba , Ahmed Raees , Mahmood Basharat
Published: February 2025

Soil, composed of inorganic and organic materials, supports diverse microbial communities, including bacteria, fungi, and yeasts, which play essential roles in compost formation. Composting is a controlled biodegradation process that converts organic waste into a nutrient-rich soil conditioner. This study aimed to compare the microbial diversity and density in two compost samples (S1 and S2) prepared on campus. Sample S1 consisted of poultry waste, vegetable waste, and fruit waste, whereas Sample S2 was composed of vegetable waste and cow dung. Microbial isolation was performed using serial dilution, spread plate, and streak plate techniques. A total of 23 microbial isolates were obtained, including 12 bacterial, 6 fungal, and 5 yeast isolates. Bacterial density was significantly higher in S1 compared to S2, suggesting a potential influence of compost composition on microbial proliferation. Identified bacterial genera included Aeromonas, Staphylococcus aureus, Pseudomonas, Edwardsiella, Salmonella, Klebsiella, Shigella, and Streptococcus sp. Fungal isolates comprised Rhizopus sp., Aspergillus sp., Fusarium sp., and Helminthosporium sp., while yeast genera included Saccharomyces, Candida, and Cryptococcus. The comparative analysis highlights the impact of compost composition on microbial diversity and suggests that poultry and fruit waste may enhance bacterial density more than cow dung-based compost. These findings provide insights into microbial contributions to compost stability and potential applications in soil conditioning and nutrient solubilization.
Supersensitive Seismic Magnetometry of White Dwarfs
Authors: Rui Nicholas Z. , Fuller Jim , Hermes J. J.
Published: February 2025

The origin of the magnetic fields in white dwarfs (WDs) remains mysterious. Magnetic WDs are traditionally associated with field strengths ≳1 MG, set by the sensitivity of typical spectroscopic magnetic field measurements. Informed by recent developments in red giant magnetoasteroseismology, we revisit the use of WD pulsations as a seismic magnetometer. WD pulsations primarily probe near-surface magnetic fields, whose effect on oscillation mode frequencies is to asymmetrize rotational multiplets and, if strong enough, suppress gravity-mode propagation altogether. The sensitivity of seismology to magnetic fields increases strongly with mode period and decreases quickly with the depth of the partial ionization-driven surface convective zone. We place upper limits for the magnetic fields in 24 pulsating WDs: 20 hydrogen-atmosphere (DAV) and three helium-atmosphere (DBV) carbon–oxygen WDs, and one extremely low-mass (helium-core) pulsator. These bounds are typically ∼1–10 kG, although they can reach down to ∼10–100 G for DAVs and helium-core WDs in which lower-frequency modes are excited. Seismic magnetometry may enable new insights into the formation and evolution of WD magnetism.
The Assembly of Supermassive Black Holes at z < 1 in Early-type Galaxies from Scaling Relations
Authors: Farrah D. , Engholm A. , Hatziminaoglou E. , Petty S. , Shankar F. , Efstathiou A. , Ejercito K. , Jones K. , Lacy M. , Lonsdale C. , Pearson C. , Tarlé G. , Windhorst R. A. , Afonso J. , Clements D. L. , Croker K. S. , Pitchford L. K.
Published: February 2025

The assembly of supermassive black hole (SMBH) mass (M
•) and stellar mass (M
*) in galaxies can be studied via the redshift evolution of the M
•–M
* relation, but the ways in which selection bias and physical assembly channels affect this evolution are uncertain. To address this, we compare the M
•–M
* relation for local massive (M
* > 1010.5
M
⊙) quiescent early-type galaxies (ETGs) to that for massive ETGs hosting active galactic nuclei (AGN) at z ∼ 0.8. The restrictions on stellar mass and galaxy type limit the assembly channels that may connect the two relations. For the local sample we find

log
(

M

•

)
=
8.80
+
1.10
(
log

M

*

−
11
)

, in line with prior work. For the z ∼ 0.8 sample we find a bias-corrected relation:

log
(

M

•

)
=
7.80
+
1.25
(
log

M

*

−
11
)

. We show, however, that this relation depends on the stellar and SMBH mass functions used to compute the selection bias, the virial relation, the virial factor, and the active fraction, which together introduce uncertainty of up to ​​​​​​∼0.6 dex in the z ∼ 0.8 relation. Adopting reasonable choices of these parameters then our z ∼ 0.8 relation lies above that for z ∼ 0 AGN by ∼0.5 dex, but below our z ∼ 0 ETG relation by 0.4–1 dex in SMBH mass. We discuss possible sources of this offset, including further bias corrections, “downsizing” in SMBH mass assembly, and preferential SMBH growth. Our results highlight the need to reduce uncertainties from selection and measurement bias in SMBH and stellar masses at all redshifts.
Food waste and loss management in HORECA: The 5C’s route guidance
Authors: Torrejon Ramos Maria , Medina-Salgado María-Sonia , Ortiz-de-Urbina-Criado Marta
Published: February 2025

Purpose: The consumption of high levels of natural resources by Hotels, Restaurants and Catering -HORECA- has a significant impact on the environment. This paper examined the evolution of food waste and loss management in HORECA Supply Chain.Design/methodology/approach: A mixed methodology is used: bibliometric analysis with SciMat software and a narrative analysis, employing both quantitative and qualitative techniques.Findings: Authors devise a general model that encompasses the fundamental research areas: the context, internal and external stakeholders, approach, drivers, process management, product or service and results or performance. Furthermore, they present the 5C’s Route Guidance, which emphasises the importance of context, raising consciousness, identifying circular models by connecting the different stages of the supply chain, and creating sustainability-oriented methods, models and products, to collectively facilitate the reduction of food waste and loss.Research limitations/implications:  The article's academic implications include defining and positioning the core issues in HORECA supply chain management, providing future research questions, conceptual guidance, and advancing the theory of food waste reduction. On a practical level, it highlights the need to improve management in HORECA companies, raise awareness and call for collaboration between academia and professionals to advance practices to reduce food waste and loss from HORECA. Socially, the use of the 5C's Route Guidance can actively contribute to the achievement of the Sustainable Development Goals.Originality/value: To identify the current knowledge structure of a complex sector such as HORECA and its role for sustainability through the application of quantitative and qualitative methodologies. The findings aid researchers in achieving more robust studies, expanding the literature on the HORECA sector and its supply chain, and guiding them to focus their studies.
Agrippa d’Aubigné et la contraction des sonnets. Les sonnets en vers lyriques dans “L’Hécatombe à Diane”
Authors: Rouget François
Published: February 2025

This article studies the sonnets of Agrippa d’Aubigné written in short verses (heptasyllables and octosyllables). In L’Hécatombe, the number of sonnets in lyric verse (generally reserved for odes and odelettes) amounts to ten and constitutes ten percent of the whole. This number invites us to reflect on their internal structures and the relationships they have with the regular sonnets that surround them. The article traces the origins of the sonnet of short verses until the beginning of the 17th century, then analyses the formal aspects of those of d’Aubigné, and finally measures the effect produced by the insertion of these short pieces within a collection where sonnets of long verses dominate. We thus see that the poet sought to extend his prosodic research as far as possible in order to give the forms a varietas which leads to their distortion.
Les “Stances” d’Agrippa d’Aubigné ou la saison de la «disperata»
Authors: Scarlatta Gabriella
Published: February 2025

This essay traces the development of the disperata and its themes in Italy and their adoption and adaptation in France, where Agrippa d’Aubigné stands as its most remarkable and faithful interpreter. In his Stances in particular, he embraces its motifs with enthusiasm and vigor and creates original and skillful interpretations. Moreover, d’Aubigné replaces love with sophisticated nuances of despair, which are used as a defense mechanism. Indeed, since love can no longer nourish his poetry in the difficult historical and political circumstances of the end of the sixteenth century, despair becomes a more compelling lyrical inspiration. Despair turns out to be not only an attractive alternative to the beloved but also the only way to write and to survive.
Os saneamentos no Ministério dos Negócios Estrangeiros. Estudo de caso sobre a Missão Diplomática Portuguesa em França
Authors: Mateus Rui Pedro
Published: February 2025

O presente artigo centra-se no processo de saneamentos no Ministério dos Negócios Estrangeiros (MNE), durante a Revolução dos Cravos utilizando a missão diplomática portuguesa em França como caso de estudo. Apresenta-se algumas características do corpo diplomático e o seu historial de relações com a comunidade portuguesa, no período antes do 25 de Abril. Em seguida, analisa-se a evolução legislativa e orgânica dos “saneamentos” e os procedimentos próprios no MNE, para no fim apontar os seus resultados, em França, aquando do fim dos trabalhos da comissão de saneamento do MNE, em março de 1976.
A rutura revolucionária na nação portuguesa resultante do 25 de Abril e as mobilizações políticas do nacionalismo cinquenta anos depois
Authors: Silva Afonso
Published: February 2025

Partindo da interrogação acerca das interações entre o 25 de Abril e a nação portuguesa, este artigo comece por destacar o caráter de rutura da democratização portuguesa. Será tida em consideração a estrutura de oportunidade criada no contexto revolucionário para uma reação ao passado, particularmente o colonial, e a reorganização de narrativas sobre o passado que caracteriza uma rutura revolucionária. Assim, ao assinalar uma redefinição da imagem da nação, reflexiona-se acerca da interação assinalada não só no âmbito de uma rearticulação do imaginário nacional resultante do 25 de Abril, como também da ativação política dos temas do passado respeitante à democratização, destacando a descolonização, por parte da nova extrema-direita em articulação com o nacionalismo português pós-25 de Abril. Deste modo, procura-se contribuir neste artigo para o estudo da Revolução Portuguesa e da sua interação com o imaginário nacional no âmbito político-ideológico neste seu 50º aniversário.
A Bionic Visual Perception Optimization Method Adapted to Multiple Signal Intensities Within GIS
Authors: Huang Jie
Published: February 2025

Bionic visual perception technology captures optical signals from gas insulated metal enclosed switchgear (GIS) partial discharge by mimicking the biological visual system, achieving real-time detection and recognition of partial discharge phenomena under complex electromagnetic environments. However, existing technologies often consider only a single spectrum and do not account for differentiated thresholds for various discharge phenomena, affecting imaging accuracy. This paper proposes a multi-spectral bionic visual perception optimization method for GIS. First, a multi-spectral bionic visual perception framework is constructed. Second, an optimization problem is formulated to maximize the average imaging accuracy of all GIS discharge phenomena. Next, a two-stage event-driven deep Q-network (DQN) optimization method is proposed, learning the optimal light intensity change threshold through two-stage closed-loop feedback, including offline and online learning. Finally, the superior performance of the proposed method is validated through simulations.
The New Technology of Intelligent Health Physical Fitness Detection Based on Mobile Terminal
Authors: Xie Ruiyun , Hou Wenzhi
Published: February 2025

Nowadays, with the rapid development of the Internet, the use of electronic mobile terminals such as mobile terminals has become very popular, and people who are at the forefront of the times are almost completely covered by electronic mobile terminals such as mobile phones. The traditional physical fitness test becomes more complicated and often needs the help of others. Therefore, this paper mainly introduces the new technology of intelligent health fitness testing based on the mobile terminal, discusses its application at home and abroad, and puts forward some suggestions for promoting physical fitness testing. The evaluation criteria of healthy physical fitness items are introduced, and make full use of the characteristics of mobile Internet to realize real-time physical fitness testing. Intelligent physical measurement is of great significance to promote the development of physical fitness testing in China.
Hump nose viper induced thrombotic thrombocytopenia purpura, prolonged AKI and complicated with with anterior STEMI.
Authors: Padmasiri Sathiesha , Sivalingam Naveenkumar , Patirana W. D. A.
Published: February 2025

No abstract available
Implications of Quercetin in Mitigating Myocardial Ischemia-Reperfusion Injury: A Review Study
Authors: Azizidoost Shirin , Adelipour Maryam , Haybar Habib , Shabaninejad Zahra , Rashidi Mojtaba
Published: February 2025

Myocardial ischemia-reperfusion injury (IRI) is introduced as a typical cardiovascular disorder with enhancing worldwide occurrence. It is generally persuaded via normal blood flow restoration to the ischemic myocardium after a recanalization period and instantly results in myocardial damage. Current investigations displays that flavonoids have the capability to function as cardioprotective agents versus IRI, which are faced in the myocardium. In this comprehensive review, we aim to delineate the therapeutic effects of quercetin in the context of myocardial IRI, shedding light on its potential as a cardioprotective agent. An up-to-date review of the literature on the cardioprotective impact of quercetin in myocardial IRI was conducted through Embase, all databases correlated to Science Direct, and Pubmed using the terms “myocardial ischemia”, “reperfusion injury” and “quercetin”. Quercetin exhibits protective effects against IRI through its anti-inflammatory, antioxidant, antiapoptotic, and calcium overload-reducing activities. The present review can emerge as a reference for planning a daily diet to prohibit or alleviate injuries following myocardial IRI and emerging flavonoids as a new window for clinical application.
A Comparative Analysis of Functional Outcomes between Lateral and Posterolateral Approaches in Total Hip Arthroplasty
Authors: Amouzadeh Omrani Farzad , Afzal Sina , Baroutkoub Mojtaba , Salimi Sohrab , Barati Hasan , Azadnajafabad Sina , Kokly Saeed , Omidian Mohammad Mehdi
Published: February 2025

Background:

Total hip arthroplasty (THA) stands as the definitive gold standard treatment for degenerative hip disorders. Various approaches have been proposed for THA, each with its own set of advantages and disadvantages. This study aimed to compare the initial functional outcomes of the lateral and posterolateral approaches to determine the approach with superior functional outcomes.

Materials and Methods:

Through a retrospective cohort study, THA candidates over a 1-year period were analyzed. Patients who underwent surgery via the lateral or posterolateral approaches were included. Demographic characteristics of patients and postoperative outcomes were compared. Patients were followed up for 1 and 6 months to evaluate their functional outcomes using the Harris Hip Score (HHS).

Results:

A total of 50 THA candidates, divided into two groups of lateral (N = 25) and posterolateral (N = 25) approaches, were evaluated in this study. Comparison of demographic data revealed a significant difference in height and body mass index between the two groups (P < 0.05), whereas age and weight showed no significant difference (P > 0.05). The mean HHS and range of motion significantly improved in each group after 6 months (P < 0.001). No significant difference was observed between the lateral and posterolateral approaches in terms of HHS and hip range of motion (P > 0.05).

Conclusion:

The results of this study demonstrate no significant difference between the outcomes of the lateral and posterolateral approaches for THA. The choice of the optimal THA approach remains contingent on the surgeon’s experience and the patient’s preference.
Understanding the PPP Syndrome: A Rare Combination of Pancreatitis, Panniculitis, and Polyarthritis
Authors: Bagheri-Ghalehsalimi Amin , Jafari Mohammad , Aria Amir , Kouchak Athar , Momenzadeh Mahnaz
Published: February 2025

Pancreatitis, panniculitis, and polyarthritis (PPP) syndrome is a rare but serious disease that can be deadly. Its symptoms come on suddenly and unexpectedly. This disease is identified by erythematous bullous skin lesions and arthritis caused by pancreatic dysfunction. A 25-year-old man had an abdominal trauma with no past medical history. A CT scan showed pancreatic inflammation, peripancreatic edema, and mild fluid in the head of the pancreas without any collection and collection of blood in the retroperitoneum. The patient came back to the hospital 2 weeks later with a fever, abdominal pain, tender joints, redness, warmth in arms and legs, and rash on the skin. In addition, their amylase and lipase levels were increased. Based on the symptoms, the patient was referred to a rheumatologist and diagnosed with PPP syndrome with concomitant pancreatitis, panniculitis, and polyarthritis. Despite being prescribed corticosteroids and broad-spectrum antibiotics, the patient passed away. The exact pathophysiology of the additional abdominal symptoms has not yet been determined. However, some researchers have suggested that this disorder may be due to the entry of pancreatic lipase enzymes into the bloodstream. Pancreatic enzymes damage adipose tissue in the lower extremities and cause panniculitis (subcutaneous adipose tissue inflammation). The symptoms of arthritis may vary depending on the clinical case as different joints are affected and the number and symmetry of joints involved may differ. Therefore, PPP syndrome is sporadic and not easily diagnosed.
Vesicouterine Cutaneous Fistula Post-cesarean Section — A Case Report
Authors: Abufraijeh Seham M. , Jankhout Seif , Al-Tah Basil , Daradkeh Abdallah , Allauzy Suhaib A.
Published: February 2025

This case report presents the diagnosis and management of a 41-year-old woman who developed a vesicouterine cutaneous fistula after a cesarean section. She initially presented with pus discharge from the cesarean wound site, and later exhibited cyclical hematuria and fluid leakage from the skin incision, prompting further investigation. Diagnostic modalities, including computed tomography with contrast, confirmed the presence of a complex fistula involving the bladder, uterus, and skin. Conservative management with gonadotropin-releasing hormone therapy was attempted but discontinued due to worsening symptoms. Surgical intervention was performed successfully, leading to the resolution of symptoms. This case underscores the importance of prompt recognition and appropriate management of rare postcesarean complications, emphasizing adherence to anatomical principles.
A New Intrauterine Adhesions Classification System: The “Loddo Score”
Authors: Loddo Alessandro , Kaza Leon , Saponara Stefania
Published: February 2025

Intrauterine adhesions (IUAs) and Asherman’s syndrome (AS) have been recognized medical conditions since the late 19th and mid-20th centuries. Multiple classification systems have been proposed to better understand their severity and implications. This article aims to provide a comprehensive overview of the existing classifications for IUAs and introduces the Loddo scoring system, a novel approach for classifying these conditions. The Loddo scoring system is unique in amalgamating the strengths of previous classifications while emphasizing the importance of ultrasonographic endometrial thickness. This new system integrates various clinical parameters, offering a holistic representation of IUAs in clinical presentation and underlying structural changes. The Loddo scoring system presents a refined approach to understand and manage IUAs, providing a precise prognosis evaluation. Bridging the diagnostic and therapeutic divide seen in past systems, it offers promise for reshaping the landscape of diagnosis and treatment in women’s health. Further research and validation are essential to assess its broad clinical applicability.
Rare Masqueraders of Pure Neuritic Leprosy: A Report of Four Cases
Authors: Sadhukhan Subhajit , Bhardwaj Abhishek , Kumar Shubham , Yadav Taruna , Patra Suman , Tiwari Sarbesh
Published: February 2025

Introduction:

Hansen’s disease is a chronic, infective granulomatous skin disease with a wide array of manifestations that resemble many dermatological and neurological conditions. Pure neuritic Hansen’s disease is a familiar form among leprosy physicians, and it poses significant diagnostic difficulty. Various disorders can mimic leprosy neuropathy clinically and these patients may receive multidrug therapy in endemic areas due to the commonality of leprosy. Hence, it is necessary to be aware of mimickers of leprosy in its various forms.

Patients and Methods:

We conducted a single-center retrospective analysis from January 2022 to June 2023. We reviewed clinical, radiological, and histopathological findings of the patients referred from neurology outpatient department which mimicked leprosy neuropathy.

Results:

We are presenting four such patients with symptoms related to neuropathy and disability. The slit skin smear was negative in all these patients, and ultrasonography, magnetic resonance imaging, and histopathology were done for diagnostic confirmation. Ultimately, all these patients were concluded to be non-leprosy cases, and an alternative diagnosis was made.

Conclusion:

Leprosy can appear in various patterns and can be mistaken for other dermatoses. Since leprosy still carries a social stigma attached to it, a wide range of dermatological and neurological illnesses must be ruled out in the differential diagnosis. These four rare entities can also mimic pure neuritic leprosy, and a thorough neurocutaneous examination complemented with appropriate radiological investigations is key to diagnosing these conditions.