bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimization of multi-echelon reverse supply chain network using genetic algorithm
Authors: Singh Guman , Rizwanullah Mohammad
Published: October 2023

Remanufacturing products has been more popular in recent years among businesses as a result of environmental concerns, and the close loop supply chain (CLSC) network has been used to optimise the reverse logistic system. The objective of the current study is to identify the ideal CLSC network, which consists of several producers, remanufacturers, intermediary centres, and customer centres. The consideration of a multi-product, multi-echelon, closed loop supply chain network (CLSC) model for returns products, in which choices about the procurement of materials and their production, distribution, recycling, and disposal play a significant part, is necessary to meet the work’s objectives. In order to resolve the issue more cheaply, a mixed-integer linear programming (MILP) approach is used. Genetic algorithm (GA) is applied as a solution approach in this.
A Study of Consumer Adoption of Chatbot in E-Commerce Sector in India
Authors: Sharma Priyanka , Satija Saumya , Yadav Dhanjay
Published: October 2023

With the advancement of technology, E-Commerce (ecom) can be an area of tremendous possibilities in terms of Artificial Intelligence (AI) driven application. In Ecom. Chatbots(cbots) are serving as flagbearers for revolutionizing accessibility and intervention, thereby addressing the growing need for customer service with a particular standard. This research documents the consumer adoption study that revolves around usage of cbots in the domain of ecom. The objective of the study is to find what the general public believes about the use of ecom Cbots as well as to identify any potential challenges or facilitators in the introduction of these Cbots. Primary research was conducted, wherein a survey had been drafted, and further analysis was done using descriptive statistics, it was found that, at present, the majority still see these cbots as a tool for seeking general information searching products and also for solving the general queries.

The Chatbot technology is in the development stage and a lot of are required to be done to replicate the conversation of a human being completely. The bot exchange still lacks empathy which makes it difficult for a computer to emulate. Users are still skeptical to trust these kinds of technology which leads to the low adoption process.
MONETARY POLICY AND ECONOMIC GROWTH OF NIGERIA: TIME-SERIES EVIDENCE FROM NIGERIA (1981-2022)
Authors:   Economics Department, Abia State University, Uturu,, Osunkwo F , Uke Kalu ,   Economics Department, Abia State University, Uturu- Nigeria, Omoruyi Pamela ,   Economics Department, Faculty of Social Sciences, University of Benin, Nigeria.
Published: October 2023

The study examined the impact of monetary policy on the economic growth of Nigeria; for the period 1981-2022. The study used Gross Domestic Product as a proxy for economic growth and employed it as the dependent variable; whereas, monetary policy rate, Cash Reserve Ratio, Treasury Bills, and liquidity rate respectively were used as the explanatory variables to measure monetary policy. Hypotheses formulated were tested using Autoregressive Distributed Lagged (ARDL) Bound co-integration test ECM. The study revealed that the Cash reserve ratio (CRR) and Treasury Bill Rate (TBR) were positive and statistically significant on Gross Domestic Product in Nigeria. Monetary Policy Rate (MPR) has a negative and is statistically significant to economic growth in Nigeria. While the Liquidity ratio had a negative and insignificant impact on Gross Domestic Product in Nigeria. The ECM result reveals that the error correction term is negative and statistically significant, and this corroborates and shows evidence of a certain return to the short-run equilibrium in the model. Therefore, the study recommends that monetary authorities should give priority attention to CRR and TBR monetary policy tools as they will produce a more desirable result in terms of economic stabilization.
INVESTIGATING THE DETERMINANTS OF CEREAL PRODUCTION IN NIGERIA
Authors:   Department of Cooperative and Rural Development, University of Agriculture and Environmental Sciences, Umuagwo, Imo State, Nzeh Innocent , Uzoechina Benedict ,   Department of Economics, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria., Imoagwu Chika ,   Department of Economics, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria., Ogwuru Hycenth ,   Department of Economics, Novena University, Ogume, Delta State, Nigeria
Published: October 2023

This study examined the factors that determine cereal production in Nigeria in two different periods; namely from 1970-2006 and from 1986-2021 using the autoregressive distributed lag (ARDL) bounds test. Findings revealed that in the two periods, cereal production was mainly influenced positively by land under cereal production and agricultural raw materials import. Also, while arable land impacted positively on cereal production in the second period, both food importation and rural population growth adversely impacted on its production. The study therefore contends that for cereal production to improve in Nigeria, land under cereal cultivation should be improved. Furthermore, while there is need to encourage the importation of more agricultural inputs in the short-run, the long-run target should be geared towards sourcing the inputs locally. It is equally the view of the study that while it is pertinent to modernize agricultural practice so that the rural inhabitants can embrace farming, excessive cereal importation should be checked to encourage local production.
ECOPRENEURSHIP AND ORGANISATIONAL PERFORMANCE: A STUDY OF QUOTED PAINT MANUFACTURING FIRMS IN NIGERIA
Authors:   Department of Business Administration and Marketing, Babcock University, Ilishan Remo Ogun State, Nigeria, Onu Christopher , Akinlabi B ,   Department of Business Administration and Marketing, Babcock University, Ilishan Remo Ogun State, Nigeria, Nneji Ngozi ,   Department of Business Administration and Marketing, Babcock University, Ilishan Remo Ogun State, Nigeria
Published: October 2023

This study investigates the impact of ecopreneurship on the organisational performance of quoted paint manufacturing companies in Nigeria. The objective of the study is to examine the dimensions of ecopreneurship, including eco-innovation, eco-production, green supply chain management, waste management, and eco-marketing, and their influence on organizational performance. The study also explores the moderating effects of environmental commitment and government regulations on this relationship. The study adopts a positivist research philosophy and employs a quantitative research approach. The study population consists of 438 employees from four paint manufacturing companies listed on the Nigerian Exchange, namely CAP Plc, Berger Paints Plc, Meyer Paint Plc, and Premier Paints Plc. Questionnaires were used as the primary data collection method, and a pilot study was conducted to validate the questionnaire. The data were analyzed using descriptive and inferential statistical methods, including multiple regression analysis and hierarchical regression analysis. The findings of the study indicate that eco-marketing has a positive and significant effect on the organizational performance of quoted paint manufacturing companies in Nigeria (β = 0.466, t = 5.195, p < 0.05). Eco-innovation (β = 0.082, t = 0.748, p>0.05) and waste management (β = 0.057, t = 0.511, p>0.05) show positive but insignificant effects, while eco-production (β = -0.136, t = -1.093, p>0.05) and green supply chain management (β = -0.051, t = -0.447, p>0.05) exhibit negative but insignificant effects on organizational performance. The overall relationship between ecopreneurship dimensions and organizational performance is positive but relatively low, with the dimensions accounting for only 9.5% of the variations in organizational performance. An environmental commitment was found to moderate the relationship between ecopreneurship and organizational performance. In conclusion, the study highlights the importance of adopting ecopreneurial practices, particularly eco-marketing, to enhance the organizational performance of quoted paint manufacturing companies in Nigeria. It emphasizes the need for a strong commitment to environmental sustainability within organizations and suggests the integration of environmentally friendly production processes. Regulators and policymakers are encouraged to formulate and enforce policies that promote ecopreneurship practices in order to ensure environmental protection and enhance organisational performance.
FAMILY BACKGROUND AND ENTREPRENEURIAL INTENTION OF SELECTED CORP MEMBERS IN OYO STATE, NIGERIA
Authors:   Department of Business Administration and Marketing, School Management Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria., Oluwatobi Lebile , Emmanuel Ajike ,   Department of Business Administration and Marketing, School Management Sciences, Babcock University, Ilishan-Remo, Ogun State, Nigeria.
Published: October 2023

Entrepreneurship Intention has been discussed in extant literature as the foundation for successful businesses. The decision of an individual to start a business is often derived from his constant interactions and consultations with his social environment. An individual who belongs to an entrepreneur-family has a greater chance to choose an entrepreneurial career than one hailing from non-entrepreneurial background. However, the effect of family background on entrepreneurial intention of corps members in Nigeria has not been fully established, which has created a literature. Therefore, this study investigated the the effect of family background on entrepreneurial intention in Nigeria. The study adopted the survey research design. 439 batch B corps members in Ibadan North, Ibadan Southwest and Ogbomoso North Local government area of Oyo State, Nigeria served as the sample unit Questionnaires were administered to the selected Corp members. Cronbach’s Alpha reliability coefficients for the constructs ranged from 0.810 to 0.827. A response rate of 87.4% was recorded from the field work. The data was analysed using descriptive and inferential tools with the aid of Statistical Package for Social Science (SPSS) version 27. Findings revealed that family background has significant effect on entrepreneurial intention selected corps members in Oyo State, Nigeria. (R= 0.551, R2= 0.304, t = 6.476 P<0.05). Specifically, the study found that Family background has a significant combined effect on entrepreneurial intention of selected corps members in Oyo State, Nigeria. (R= 0.568 R2= 0.323, AdjR2 0.293 F(4, 380) = 10.958 P<0.05). The study concluded that there is significant relationship between family background and entrepreneurial intention, with a moderate positive correlation. The study therefore recommended that Youth corps members should understand the potential influence of family business experience and entrepreneurial education on their entrepreneurial competence and knowledge. Reflect on the experiences and knowledge gained from family businesses and leverage them to enhance your entrepreneurial abilities.
Farm Friendly Chat Bot
Authors: Komal Mandal  , Nikita Bhokare  , Ketki Gaidhani  , Chanchal Bavisker  , Prof. M. D. Sanap
Published: October 2023

This study presents the development of a chat room and a chatbot designed to facilitate discussions on prevalent farming issues among peers and experts. Its primary aim is to provide timely support to farmers in making informed decisions about their farming practices. To create a structured framework for these conversations, a standardized set of questions was formulated through consultations and surveys involving farmers, experts, and other stakeholders. The questions were analyzed to extract 'intents,' representing the specific information or assistance users might seek, and 'examples,' which are concrete instances users provide to express their particular intent. Additionally, 'entities' were identified to represent distinct objects or concepts related to these intents. The model was trained using the Artificial Intelligence Markup Language (AIML) to predict the intent based on the provided examples. This training process enhances the chatbot's ability to understand and respond to user queries effectively. Furthermore, the chatbot was deployed on a cloud platform, reducing the computational resources required on the client end. This approach ensures accessibility and usability for a broader user base without significant hardware constraints.
Teachers’ Perceptions of Blended Learning and the Acquisition of Language Skills in National and Extra-County Schools in Western Region, Kenya
Authors: Lillian Wasike Nekesa , Mutsotso Stanley Ngome , Wasike Duncan Wekesa
Published: October 2023

In order to meet the 21st Century threshold of global quality education, there is a need to adopt more modern technology in the classroom; a need further aggravated by Covid-19 which recently interrupted education worldwide. It is against this backdrop and the unsatisfactory KCSE performance in languages, that this study sought to investigate Perceptions of Teachers on the use of Blended Learning in learners’ acquisition of English language skills in National and Extra-County schools in Western region, Kenya. The main objective was to establish Teachers’ Perceptions towards use of blended learning in enhancing learners’ acquisition of English reading and writing skills in National and Extra-County schools in Western region, Kenya. This study was based on Social Constructivism and Connectivism theories by Lev Vygotsky and George Siemens respectively. The sample was 32 Language Teachers;16 Principals; 4 CQASOs and 2 KICD language specialists. The study sample was 54 respondents selected through simple random and purposive sampling techniques. The design adopted was Descriptive Survey. Data was collected through 2 instruments: an interview schedule and a questionnaire. The data was analyzed using descriptive and inferential statistics using SPSS. For the purpose of analysis; the schools in the study were divided into High and Low Achievers’ schools. The study findings also showed that higher levels of acquisition of language skills in High Achievers’ schools were attributable to positive perceptions by teachers towards use of blended learning, for which a significant difference was established (t (32)=1.0067). The study concluded that the availability and frequent use of blended learning positively impact teachers’ perceptions towards the use of blended learning and influence learners’ acquisition of English language skills. This study recommends that the use of blended learning be encouraged and there should be sustained teacher professional development to equip teachers with relevant skills to enable them to use blended learning.
Capital extranjero y gestión local: La Compañía Italo-Argentina de Electricidad, 1912-1950
Authors: Barbero María Inés , Lanciotti Norma Silvana
Published: October 2023

El artículo analiza la trayectoria de la Compañía Ítalo-Argentina de Electricidad desde su creación en 1912 hasta 1950, momento en el cual se produjeron cambios estructurales en la modalidad de gestión y en la propiedad de los sistemas eléctricos tanto a nivel global como en la Argentina. Evaluamos los orígenes de la compañía, la conformación del grupo inversor y el estilo de financiamiento, así como su trayectoria tecnológica en relación con las condiciones institucionales que incidieron en el sector eléctrico. El trabajo se basa en el análisis de archivos y publicaciones de las empresas eléctricas y compañías holding (Archivo Histórico Pirelli, Memorias y balances de CIAE, Memorias y balances de CHADE, Memorias y Balances de CATE, Memorias y Balances de la SSAE), informes y publicaciones de gobierno (Antecedentes de las concesiones, Informes de las comisiones investigadoras, Documentación y legajos sobre electricidad en el Archivo General de la Nación) y publicaciones periódicas (Boletín de la Bolsa de Comercio, Monitor de Sociedades Anónimas, The Argentine Year’s Book).
Migración a la Argentina y regreso a Italia. Las actividades empresariales de Juan Giol en la Región del Véneto, 1912-1930
Authors: Olguín Patricia
Published: October 2023

Los migrantes europeos que retornaron a sus países de origen en la era de la inmigración masiva que se inició en la década de 1880 y concluyó con el estallido de la Primera Guerra Mundial siguieron itinerarios diversos. Este trabajo se propone analizar las actividades económicas desarrolladas por Juan Giol -un inmigrante italiano devenido en un empresario vitivinícola exitoso en Argentina- que regresó a la patria en 1915 y puso en marcha una empresa agroindustrial diversificada en la región del Véneto, la cual dirigió desde 1915 y hasta su muerte en 1936. Sobre la base de un conjunto de documentos empresariales y personales inéditos pertenecientes a Juan Giol, se pretende reconstruir el proceso de inversión en explotaciones rurales iniciado en Italia antes del retorno, estudiar el funcionamiento y los resultados económicos de la Azienda Giol, conocer su relación con el capital acumulado y los negocios emprendidos en Argentina y reconstruir las redes de relaciones familiares, económicas y sociales tendidas a ambos lados del Atlántico. El estudio realizado revela una sangría de fondos transferidos desde Argentina a la Azienda Giol, que llegó a más que triplicar los beneficios promedio producidos por las unidades de negocios entre 1913 y 1930.
Investigating the Differences & Similarities: A Comparison of Turkish and Pakistani Media Educational Systems
Authors: FAHİM M. , ISLAM Md Nazmul
Published: October 2023

This article is an attempt to compare the Pakistani and Turkish media educational systems with the view of revealing the similarities and differences between them. The novelty of the research lies in the fact that there are no previous studies attempted at examining and comparing Pakistan’s and Türkiye’s media educational systems. The study comprises 10 media faculties/departments of public sector universities from each country under study and applies descriptive content analysis to investigate the underpinned research subject through the websites and prospectuses of the faculties and/or departments. The present research lays out theoretical dimensions and statistics of Türkiye and Pakistan’s media educational systems, comparing and contrasting the statistical figures in terms of Ph.D and/or non-Ph.D faculty members, foreign Ph.D faculty members, male-female ratio, degree programs, facilities (campus radio station, TV station), publications, the ranking of the media faculties and departments. This comparative study aims at highlighting the gaps and proposing solutions for improving the quality of Pakistan’s media educational system, as media is an integral part of our society and it is the fourth estate.
Alternatives for the scientific production evaluation for the Social Sciences. A look from technoscience as a social phenomenon
Authors: Ortiz Núñez Roelvis
Published: October 2023

The evaluation of science is a subject that has generated debates and tensions in the scientific and academic community. The dominant model for the evaluation of scientific activity presents a series of criticisms and limitations, with special emphasis on the field of Social Sciences. In order to propose solutions to this phenomenon, the research formulates as a general objective to develop an alternative model of scientific production evaluation for the Social Sciences field, from the perspective of technoscience as a social phenomenon. The research raises methodological triangulation, by integrating qualitative and quantitative analysis approaches, which include methods and techniques such as bibliographic review, application of traditional metrics and alternative science measurement, as well as the application of interviews, surveys and the Delphi method. An analysis of the state of the matter was carried out, which made it possible to identify the questions, criticisms and limitations of the science evaluation processes, which contributed to establishing a balance in relation to the contributions, discussions, inputs, referential frameworks, conceptions, approaches and perspectives. The proposal is based on the techno-scientific changes introduced in the knowledge production that allow a complementation between the knowledge production and society. From this perspective, the quality and relevance of the scientific research results, epistemological diversity and the active participation of the academic and social community are promoted.
Estrategias para el fortalecimiento institucional
Authors: Castellanos Espinoza Esther Briggitte
Published: October 2023

El presente trabajo de investigación tiene como objetivo identificar cuales son los factores que han ocasionado que Presto tenga un nivel de ingresos bajo en los últimos 3 años para la creación de estrategias a partir de la matriz FODA que permitan lograr un fortalecimiento institucional de la compañía. Para efectos de este estudio se aplicó un enfoque cualitativo, el tipo de investigación es el descriptivo con un diseño narrativo, para lo cual se entrevistó al Gerente General y realizó una observación directa no participativa durante 20 días al personal en horario laboral. Los resultados arrojaron que existen dos grandes problemas, el marketing y los costos elevados, para lo cual se deben aplicar las estrategias planteadas.
Incidencia del teletrabajo en la productividad laboral de la Dirección Provincial del Consejo de la Judicatura de Manabí
Authors: Macías Villafuerte Yenny María , Bravo Giler María Amelia , Zambrano Zambrano María Inés
Published: October 2023

Esta investigación tiene relevancia debido al creciente interés en el teletrabajo como resultado de la pandemia de COVID-19. La contribución académica del estudio radica en su aporte a la comprensión y conocimiento sobre los efectos del teletrabajo en la productividad laboral. Desde una perspectiva práctica, los hallazgos pueden ser utilizados por la Dirección Provincial del Consejo de la Judicatura de Manabí para evaluar y ajustar sus políticas y prácticas relacionadas con el teletrabajo. Es importante destacar que esta investigación se basa en un enfoque cuantitativo. Sin embargo, al tratarse de una investigación no experimental, los resultados reflejan la percepción de los participantes en el momento de la encuesta y no se pueden establecer relaciones de causalidad directa entre el teletrabajo y la productividad laboral. No obstante, los hallazgos respaldan la idea de que el teletrabajo puede tener un impacto positivo en la productividad y satisfacción laboral de los servidores.
First report of Fusarium oxysporum f. sp. niveum race 1 as causal agent of vascular wilt of watermelon in Mexico
Authors:   Centro de Investigación en Alimentación y Desarrollo, A.C. México, Vargas-Arispuro Irasema , Ramírez-Bustos Irene Iliana ,   Universidad Estatal de Sonora. México, Arratia-Castro Alda Alejandra ,   Universidad Politécnica de Pénjamo. México, Bárcena-Santana Daniel ,   Universidad Estatal de Sonora. México, Fernández-Herrera Ernesto ,   Universidad Estatal de Sonora. México
Published: October 2023

Vascular wilt (Fusarium oxysporum f. sp. niveum [Fon]) is the main fungal disease of watermelon crops worldwide and can be caused by any of the four known races of this fungus (race 0, 1, 2 and 3). In Mexico, there are no reports of the presence of any of these races. The presence of plants with wilt and vascular necrosis has been observed in commercial watermelon plantations in the municipality of Hermosillo, Sonora, Mexico, mainly during the spring-summer growing seasons. The aim of this study was to identify the Fon race causing vascular wilt in watermelon plants in Hermosillo, Sonora. Three fungal isolates were collected from symptomatic plants. Based on their morphological characteristics, DNA amplification of the isolates (with specific primers Fon-1/Fon-2, FONSIX6F/FONSIX6R and FNR3-F/FNR3-R, which allow differentiating Fon race 1, 2 and 3) and inoculation into three differential watermelon cultivars, the three isolates (UESFON01, UESFON02 and UESFON03) were identified as F. o. f. sp. niveum race 1. To our knowledge, this is the first report where F. o. f. sp. niveum race 1 is identified as the causal agent of wilt, vascular necrosis and plant death in watermelon crops in Mexico.
Automatic identification of avocado fruit diseases based on machine learning and chromatic descriptors
Authors:   Colegio de Postgraduados, Campus Montecillo. México, Campos-Ferreira Ulises Enrique , González-Camacho Juan Manuel ,   Colegio de Postgraduados, Campus Montecillo. México, Carrillo-Salazar José Alfredo ,   Colegio de Postgraduados, Campus Montecillo. México
Published: October 2023

Timely identification of phytosanitary problems in agricultural crops is essential to reduce production losses. Artificial intelligence algorithms facilitate their rapid and reliable identification. In this research, three learning classifiers, namely random forest (RF), support vector machine (SVM) and multilayer perceptron (MLP), were evaluated to identify three target classes (healthy fruit, anthracnose [Colletotrichum spp.] and scab [Sphaceloma perseae]) from digital fruit images. Two color descriptor extraction techniques (region selection and image subsampling) were compared with the RF classifier, and an overall classification accuracy (ACC) of 98±0.03 % with region selection and 84±0.08 % with subsampling was obtained. Subsequently, the classifiers were evaluated with color descriptors extracted with region selection. RF and MLP were superior to SVM, with an ACC of 98±0.03 %. Scab and anthracnose were identified with an F1 score of 98 %. %. The high performance of the classifiers shows the potential for applying artificial intelligence paradigms to identify phytosanitary problems in agricultural crops.
Marchantas de la Región Capital de Veracruz: los saberes alimentarios de una actividad productiva/comercial
Authors: Mendoza López Laura , Barón León María de Lourdes
Published: October 2023

En la ciudad de Perote, cabecera del municipio homónimo, perteneciente a la Región Capital de Veracruz, se les llama marchantas a las campesinas provenientes de otros municipios de la región, que se dedican a vender de puerta en puerta alimentos tradicionales de temporada, cultivados en huertos de traspatio por ellas o sus familias. El objetivo de este artículo consiste en visibilizar los saberes alimentarios que poseen las marchantas para poder desarrollar su actividad productiva/comercial y a través de quién o quiénes les fueron transmitidos. Estos saberes incluyen: cómo y dónde se obtienen, la forma de prepararlos, servirlos, además de consumirlos; a conocer las temporadas, los sitios y técnicas necesarias para obtenerlos, etc. (Aguirre, 2016; Troncoso, 2019). Através de un censo, entrevistas a profundidad, así como observación participante, se identificaron los saberes alimentarios que ellas poseen, así como de quiénes y cómo los adquirieron. Se encontró que las marchantas aprenden desde la infancia, y, como veremos, son de particular importancia en este proceso de aprendizaje, las mujeres de la familia y la comunidad, así como de algunos familiares hombres, en ciertas etapas de la transmisión de los saberes.
Representaciones territoriales y actores sociales en la reconfiguración territorial de San Miguel Xaltocan
Authors: Vega Vega Luis Eduardo , Llanos Hernández Luis , Hernández Aguilar Gerardo Porfirio
Published: October 2023

En 2019, el gobierno federal negoció con los pobladores de San Miguel Xaltocan los terrenos de uso agrícola para la construcción del megaproyecto Aeropuerto Internacional Felipe Ángeles (AIFA), y prometió a cambio la realización de varios proyectos de beneficio social en el territorio. Este contexto generó un ambiente de negociación y conflicto entre el gobierno y los actores sociales de la comunidad, un proceso muy complejo debido a la multiplicidad de intereses y diferentes formas de percibir su territorio. Las representaciones territoriales presentes en los actores sociales influyeron en la reconfiguración del espacio-territorio a través de procesos de apropiación y proyección territorial a largo plazo. En estas representaciones están inmersas algunas percepciones que constituyen oportunidades, esperanzas y riesgos. El objetivo del estudio fue interpretar cómo las representaciones territoriales influyen en la reconfiguración del territorio. El estudio se desarrolló bajo el enfoque cualitativo con las técnicas de entrevista semiestructurada, recorrido de campo, la representación gráfica proyectada en el recuerdo de las personas y la revisión documental.
An unusual cause of abdominal pain: spontaneous bilateral adrenal hemorrhage
Authors: Rodriguez Tebar A , Panza-Nduli J , Gubin B , Rogghe P-A , Oriot P
Published: October 2023

Bilateral adrenal hemorrhage (BAH) is a rare condition that can lead to acute adrenal insufficiency and death if not recognized and treated promptly. We report the case of a 30-year-old male who presented to the emergency department with acute abdominal pain, nausea, and vomiting. On emergency room admission, the first abdominal CT revealed normal adrenal glands without enlargement, but with the development of hypotension and hypoglycemia, a second CT performed four days later showed enlargement due to hemorrhage in both adrenals. The diagnosis of BAH associated with acute adrenal insufficiency was retained. Prompt treatment with intravenous and oral corticosteroids resulted in successful conservative management. We describe the clinical, biological, radiological and etiological features of this condition based on a review of the literature.
ERLIQUIOSE MONOCÍTICA CANINA: ATUALIDADES SOBRE A DOENÇA
Authors: Caetano Isabela Rodrigues , Costa Bruna Goulart , Paulino Junior Daniel
Published: October 2023

O principal patógeno causador da erliquiose nos cães, é a Erlichia canis. Sua transmissão depende do vetor, Rhipicephalus sanguineus, carrapato que passa a doença para os cães através do repasto sanguíneo, pela inoculação da saliva. Ocorre em regiões de clima tropical. Essa afecção é multissistêmica, com sinais clínicos inespecíficos, o que dificulta o seu diagnóstico e tratamento de maneira precoce. Divide-se nas fases aguda, subclínica e crônica. Seu diagnóstico é baseado no histórico, anamnese, exame físico e exames complementares. O exame mais utilizado é o teste rápido dot-ELISA, porém, o exame que apresenta diagnóstico definitivo é o PCR. Um dos achados laboratoriais mais comuns é a trombocitopenia, porém deve-se diferenciar de outras doenças que também apresentam essa alteração e que são transmitidas pelo mesmo vetor. O tratamento eficaz é com antibioticoterapia e terapias de suporte que visam a remissão dos sinais clínicos. O medicamento preconizado é a doxiciclina. Não há um método totalmente eficaz de prevenção da doença ou de controle do vetor para que não haja sua propagação em grande escala. Por isso, as medidas tomadas são relacionadas ao controle do vetor, nos animais e no ambiente. São utilizados medicamentos pour on, spot on, coleiras, e as isoxazolinas. Há também, os óleos essenciais, como o de Cravo-da-Índia, para controle ambiental, como possibilidade para o futuro. Esse trabalho tem como objetivo realizar uma revisão de literatura atual sobre a doença, abordando seus principais aspectos, dentre eles, definição, etiologia, epidemiologia, patogenia, sinais clínicos, diagnóstico, tratamento, prognóstico, controle e prevenção.
REPRESENTATIVE AND ILLUMINIST CONSTITUTIONAL JURISDICTION: AN OUTLOOK BASED ON THE HERMENEUTICAL CRITICISM OF LAW
Authors: Rodrigues Josenilson
Published: October 2023

The present study analyzed the representative and illuminist role of the Constitutional Courts (Barroso) under the lens of the Hermeneutic Criticism of Law (Streck). The objective was to understand, based on these theoretical matrices, what to expect from Brazilian constitutional jurisdiction to adequately meet the constitutional project inaugurated in 1988. An approach was made to the representative and illuminist role of the Constitutional Courts and the Hermeneutic Criticism of Law (HCL) and, at the end, an analysis of the representative and illuminist role of the Constitutional Courts based on the HCL. It was noted that HCL offers elements that are best suited to the democratic implementation of the constitutional project inaugurated in 1988.
ELUCIDAÇÕES SOBRE A NANOTECNOLOGIA NA DOENÇA DO ALZHEIMER: REVISÃO DA LITERATURA
Authors: Barbosa Anna Heloísa Lemos , Novais Caroline dos Santos , Ribeiro Francielen Letícia Silva , Andrade Hudson Holanda de
Published: October 2023

A doença do Alzheimer (DA), é uma condição neurodegenerativa que tem como característica a presença de placas fibrilares amiloides extracelulares, composta por um peptídeo conhecido por β-amiloide. Ao longo dos anos, diversos pesquisadores vêm se dedicando a encontrar novos métodos de diagnóstico e tratamento para a DA, no entanto as diligências não apresentaram resultados significativos em relação à doença. Porém com o avanço da tecnologia e sua inserção no meio da pesquisa e saúde, é possível obter novas expectativas, através do uso da nanotecnologia como forma de combate à doença. Desta forma, o presente artigo apresenta informações bibliográficas com base nos principais artigos científicos associados a nanotecnologia e Alzheimer, visando levar conhecimento e informação para profissionais da saúde e a comunidade interessada. Este trabalho tem como objetivo identificar o potencial da utilização de nanopartículas no tratamento da doença de Alzheimer e identificar tratamentos promissores e quais são seus possíveis efeitos colaterais conduzindo uma Revisão narrativa da literatura baseada em consulta a repositórios como Science Direct, Web of Science, PubMed e Scielo. Como resultado se observou que as nanopartículas são capazes de atravessar a barreira hematoencefálica (BHE) e transportar os medicamentos necessários para a inibição da agregação de peptídeos Aβ, resolvendo fibrilas preexistentes. Polímeros biodegradáveis e biocompatíveis, como polilactida de polietilenoglicol (PLGA), representa uma abordagem promissora e segura e tem sido amplamente utilizada. As melhores tecnologias são aquelas que incluem nanopartículas, capaz de atravessar a barreira hematoencefálica (BHE) para atingir alvos terapêuticos e garantir que essas moléculas não causem efeitos nocivos, tóxico para o corpo. Embora as nanopartículas sejam eficazes no tratamento de algumas doenças, pouco se sabe sobre os seus efeitos secundários, estes medicamentos podem ou não ser mais prejudiciais ao organismo do que a doença que pretendem tratar. Conclui-se que existem muitos tratamentos promissores, mas ainda não foram aprovados devido à dificuldade de manter concentrações adequadas do medicamento no espaço intraneural. A determinação da dose tóxica é necessária para aprovar o uso de nanopartículas no tratamento, mas é quase impossível, pois seus efeitos citotóxicos em regiões extraneural são imprevisíveis, sendo necessário mais estudos com os nanomateriais para tratamento de Alzheimer.
EFEITOS ADVERSOS NO USO DO ÁCIDO HIALURÔNICO INJETÁVEL EM PREENCHIMENTOS FACIAIS: REVISÃO NARRATIVA
Authors: Carvalho Yandra Danielle da Silva , Lucena Amanda Dourado de , Costa Andrea de Andrade Souza , Andrade Ikaro Alves de
Published: October 2023

O Biomédico esteta pode realizar vários procedimentos faciais minimamente invasivos. No entanto, os cuidados e a segurança dos pacientes devem ser priorizados mediante as possíveis complicações resultantes deste tratamento. Nesse sentido o objetivo desta revisão narrativa é compreender o papel do biomédico esteta frente às implicações e os efeitos adversos do uso do ácido hialurônico injetáveis em preenchimentos faciais. Existem uma variedade de reações adversas, abrangendo desde edema e equimose localizados até complicações mais sérias, como infecções e necrose tecidual. Ao destacar de forma criteriosa os efeitos adversos associados ao ácido hialurônico, este estudo proporciona uma visão abrangente dos riscos inerentes a essa intervenção estética. Tais informações são cruciais para embasar a prática do profissional biomédico esteta, permitindo a adoção de medidas preventivas e a seleção criteriosa de pacientes, visando minimizar tais efeitos e promover resultados seguros e satisfatórios. A presente discussão não apenas contribui para o aprimoramento da prática clínica, mas também preenche uma lacuna no corpo de conhecimento atual sobre os efeitos adversos do ácido hialurônico em procedimentos faciais. Com base em evidências sólidas, busca-se assim promover uma abordagem informada e responsável no contexto da estética biomédica.
USO INDISCRIMINADO DE NIMESULIDA
Authors: Castro Thamiris da Silva Correia , Andrade Leonardo Guimarães de
Published: October 2023

Os Anti-inflamatórios não esteroides (AINES) são a classe de medicamentos mais prescritos e vendidos no mundo, são utilizados para evitar e/ou dificultar um processo inflamatório causado por uma infecção ou lesão. A nimesulida surgiu em 1985 e passou a ser comercializada em mais de 50 países. Em virtude de seu potencial terapêutico, este medicamento acaba sendo usado em larga escala no Brasil. Seu mecanismo de ação está associado à inibição das enzimas ciclo-oxigenases, preferencialmente da COX-2. A menor afinidade pela COX-1 reduz os efeitos adversos que os AINEs podem causar Contudo, com o passar dos anos, alguns estudos científicos demonstraram a presença de uma grave reação adversa: são evidenciados problemas gastrintestinais, cardiovasculares, hepáticas, cerebrovasculares, renais, trombóticos, gestacionais e fetais, aumentando o índice de morbimortalidade. É nessa circunstância que entra a importância da atuação do farmacêutico, assumindo papel essencial na avaliação e orientação do paciente quanto à farmacoterapia prescrita pelo médico.
Global estimates of 100-year return values of daily precipitation from ensemble weather prediction data
Authors: Ruff Florian , Pfahl Stephan
Published: October 2023

Abstract. High-impact river floods are often caused by very extreme precipitation events with return periods of several decades or centuries, and the design of flood protection measures thus relies on reliable estimates of the corresponding return values. However, calculating such return values from observations is associated with large statistical uncertainties due to the limited length of observational time series. Here, 100-year return values of daily precipitation are estimated on a global grid based on a large data set of model-generated precipitation events from ensemble weather prediction. In this way, the statistical uncertainties of the return values can be substantially reduced compared to observational estimates. In spite of a general agreement of spatial patterns, the model-generated data set leads to systematically higher return values than the observations in many regions, with statistically significant differences, for instance, over the Amazon, western Africa, the Arabian Peninsula and India. This may point to an underestimation of very extreme precipitation events in observations, which, if true, would have important consequences for practical water management.
Salt intrusion dynamics in a well-mixed sub-estuary connected to a partially to well-mixed main estuary
Authors: Lin Zhongyuan , Zhang Guang , Zou Huazhi , Gong Wenping
Published: October 2023

Abstract. Salt intrusion in estuaries has been exacerbated by climate change and human activities. Previous studies have primarily focused on salt intrusion in the mainstem of estuaries, whereas those in sub-estuaries (those branch off their main estuaries) have received less attention. During an extended La Niña event from 2021 to 2022, a sub-estuary (the East River estuary alongside the Pearl River Estuary, China, experienced severe salt intrusion, posing a threat to the freshwater supply in the surrounding area. Observations revealed that maximum salinities in the main estuary typically preceded spring tides, exhibiting significant asymmetry in salinity rise and fall over a fortnightly timescale. In contrast, in the upstream region of the sub-estuary, the variation of salinity was in phase with that of the tidal range, and salinity rise and fall exhibited more symmetrical. Inspired by these observations, we employed idealized numerical models and analytical solutions to investigate the underlying physics behind these behaviors. It was discovered that under normal dry condition (with a river discharge of 1500 m3 s-1 at the head of the main estuary), the river-tide interaction and change in horizontal dispersion accounted for the in-phase relationship between the salinity and tidal range in the upstream region of the sub-estuary. Under extremely dry conditions (i.e., a river discharge of 500 m3 s-1 at the head of the main estuary), salinity variations kept pace with those of the tidal range from the middle to upstream regions of the sub-estuary. The variation of salinity in the main estuary, along with those of salt dispersion and freshwater influx inside the sub-estuary collectively influenced salinity variation in the well-mixed sub-estuary. These findings have important implications for water resource management and salt intrusion prevention in the catchment area.
G6-1.5K-SAI: a new Geoengineering Model Intercomparison Project (GeoMIP) experiment integrating recent advances in solar radiation modification studies
Authors: Visioni Daniele , Robock Alan , Haywood Jim , Henry Matthew , Tilmes Simone , MacMartin Douglas G. , Kravitz Ben , Doherty Sarah , Moore John , Lennard Chris , Watanabe Shingo , Muri Helene , Niemeier Ulrike , Boucher Olivier , Syed Abu , Egbebiyi Temitope S.
Published: October 2023

Abstract. The Geoengineering Model Intercomparison Project (GeoMIP) has proposed multiple model experiments during the phases 5 and 6 of the Climate Model Intercomparison Project (CMIP), with the latest set of model experiment proposed in 2015. With phase 7 of CMIP in preparation, and with multiple efforts ongoing to better explore the potential space of outcomes for different Solar Radiation Modification (SRM) both in terms of deployment strategies and scenarios and in terms of potential impacts, the GeoMIP community has identified the need to propose and conduct a new experiment that could serve as a bridge between past iterations and future CMIP7 experiments. Here we report the details of such a proposed experiment, named G6-1.5K-SAI, to be conducted with the current generation of scenarios and models from CMIP6, and clarify the reasoning behind many of the new choices introduced. Namely, compared to the CMIP6 GeoMIP scenario G6sulfur, here we decided on: 1) an intermediate emission scenario as baseline (the Shared Socioeconomic Pathway 2-4.5); 2) a start date set in the future that includes both considerations around the likelihood of exceeding 1.5 ºC above preindustrial and some considerations around a likely start date for an SRM implementation; 3) a deployment strategy for Stratospheric Aerosol Injection that does not inject in the tropical pipe in order to obtain a more latitudinally uniform aerosol distribution. We also offer more details over the preferred experiment length and number of ensemble members, and include potential options for second-tier experiments some modeling groups might want to run. The specifics of the proposed experiment will further allow for a more direct comparison between results obtained with CMIP6 models and those obtained with future scenarios for CMIP7.
Wind Farm Structural Response and Wake Dynamics for an Evolving Stable Boundary Layer: Computational and Experimental Comparisons
Authors: Shaler Kelsey , Quon Eliot , Ivanov Hristo , Jonkman Jason
Published: October 2023

Abstract. The wind turbine design process requires performing thousands of simulations for a wide range of inflow and control conditions. This necessitates computationally efficient yet time-accurate models, especially when considering wind farm settings. To this end, FAST.Farm is a dynamic wake meandering-based midfidelity engineering tool developed by the National Renewable Energy Laboratory targeted at accurately and efficiently predicting wind turbine power production and structural loading in wind farm settings, including wake interactions between turbines. This work is an extension to a study into constructing a diurnal cycle evolution based on experimental data. Here, this inflow is used to validate the turbine structural and wake meandering response between experimental data, FAST.Farm simulation results, and high-fidelity large-eddy simulation results from coupled SOWFA-OpenFAST. The validation occurs within the nocturnal stable boundary layer when corresponding meteorological and turbine data were available. To that end, load results from FAST.Farm and SOWFA-OpenFAST are compared to multi-turbine measurements from a subset of a full-scale wind farm. Computational predictions of blade-root and tower-base bending loads are compared to 10-minute statistics of strain gauge measurements during 3.5 hour of the evolving stable boundary layer, generally with good agreement. This time period coincided with an active wake steering campaign of an upstream turbine, resulting in time-varying yaw positions of all turbines. Wake meandering was also compared between the computational solutions, generally with excellent agreement. Simulations were based on the use of a high-fidelity precursor constructed from inflow measurements and using state-of-the-art mesoscale-to-microscale coupling.
Vegetation on expansive clay soils from Madrid and La Sagra region (Madrid-Toledo, Spain)
Authors: Luengo Enrique , Magaña Ugarte Rosina , Martínez Labarga Juan Manuel , De Pablo Sanz Rubén , Sánchez-Mata Daniel
Published: October 2023

Soils rich in expansive clays (i.e., smectite and montmorillonite, and, to a lesser extent, soft clays such as sepiolite and palygorskite) are found in a broad stretch running NNE-SSW from the east of Madrid to the Tagus River surrounds in the province of Toledo. These clays tend to give rise to a specific type of soil, known as "vertisols" or related argillic soils with vertic behaviour, varied chemical and sedimentological composition, and occasionally siliceous or dolomitic clasts. In these soils, where there is an absence of woody vegetation, the colonising nitrophilous vegetation becomes of particular interest through the usage and alteration of the land. These argillic soil plant communities are incredibly diversified, with flora suited to the unique hydrogeochemical conditions of these settings. The variety of these plant communities is determined by factors such as land use, lithology, terrain, and the level of humidity they can withstand. We identify the primary plant community on the Madrid-Toledo expansive clays in this paper, as well as provide a preliminary approach to the different varieties and transitions to other related plant communities. The main dynamic and catena links are established, and a floristically summarised table is provided, along with a descriptive examination of the community's behaviour and variability. Finally, its conservation status and the high degree of threat to which it is subjected are assessed.
Analyzing the Writ Jurisdiction of High Courts: A Case Study from Pakistan
Authors: Qureshi Gohar Masood , Shahid Anum , Chaudhary Faiza
Published: October 2023

The primary and the most important function of judiciary in a country is to establish the rights of the citizens and to safe guard the same. And thus, to enforce the fundamental rights laid down in the constitution. In Pakistan, the judiciary either higher or the subordinate performing the same functions with true sprite, following the constitution and the statutory laws to ensure that every citizen is guaranteed his fundamental rights in light of Article 9 of the Constitution of Islamic Republic of Pakistan. In this research paper, the role of high courts will be discussed under article 199 of the constitution, and this research paper will unfold the power of high courts to enforce fundamental rights. In this paper, the writ jurisdiction of the high court will be explained related to the establishment of fundamental rights.