bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioprinting technology for the management of diabetic foot disease: Emerging applications, challenges, and prospects
Authors: Xu Fan , Rui Shunli , Yang Cheng , Jiang Xiaoyan , Wu Wei , Tang Xianlun , G. Armstrong David , Ma Yu , Deng Wuquan
Published: August 2023

Most conventional therapies have limitations in the repair of complex wounds caused by chronic inflammation in patients with diabetic foot ulcers (DFUs). In response to the demand for more biotechnology strategies, bioprinting has been explored in the regeneration field in recent years. However, challenges remain regarding the structure of complex models and the selection of proper biomaterials. The purpose of this review is to introduce the current applications of bioprinting technology in chronic diabetic foot wound healing. First, the most common application of bioprinting in producing skin equivalents to promote wound healing is introduced; second, functional improvements in the treatment of chronic and difficult-to-heal DFU wounds facilitated by bioprinting applications are discussed; and last but not least, bioprinting applications in addressing unique diabetic foot disease characteristics are summarized. Furthermore, the present work summarizes material selection and correlations between three-dimensional (3D) bioprinting and a variety of biomimetic strategies for accelerating wound healing. Novel, biotechnological tools such as organoids for developing new biomaterials for bioprinting in the future are also discussed.
 
Advances of 3D printing in gastroenterology and where it might be going
Authors: Zhang Yuhang , Chen Liuxiang , Hu Bing
Published: August 2023

Gastrointestinal (GI) system comprises a great number of organs and tissues of various functions, both hollow and solid. However, it is still a less well-developed area for three-dimensional (3D) printing (3DP) applications compared to orthopedics. Clinical applications of 3DP in the GI system are presently restricted to preoperative planning, surgical guidance, and education for students, residents, and patients, either for laparoscopy or endoscopy. Several surgery-related accessories have been designed to facilitate surgical procedures. The results are promising but not adequately proven due to a lack of reasonable study design and proper comparisons. Other important requirements for GI systems in clinical scenarios are structural reconstruction, replacement, defect repair, drug screening, and delivery. Many 3D-printed decellularized, cell-seeded, or even bioprinted scaffolds have been studied; however, most studies were conducted on small animal or in vitro models. Although encouraging results have been obtained, there is still a long way to go before products compatible with humans in size, histology, and functions can be printed. The key points to achieving this goal are the printing material, cell type and source, and printing technology. The ultimate goal is to print tissue and organ substitutes with physiological functions for clinical purposes in both time- and cost-effective ways.
Development of a 3D-printable matrix using cellulose microfibrils/guar gum-based hydrogels and its post-printing antioxidant activity
Authors: Emmanuel Adedeji Olajide , Hyun Min Ju , Eon Park Gi , Jee Kang Hye , Choi Ji-Young , Aminu Mariam Omowunmi , Boniface Ocheme Ocheme , Joo Seon-Tea , Moon Kwang-Deog , Jung Young Hoon
Published: August 2023

A biomaterial ink suitable for three-dimensional (3D) printing was developed using cellulose microfibrils (CMFs, 1% w/v) and guar gum (1–7 g/100 mL CMFs), and the post-printing stability and antioxidant functionality of the borax-treated construct were investigated. Rheological analysis, Fourier transform infrared spectrometry, X-ray diffractometry, and scanning electron microscopy revealed the suitability of the two polymers to form an interpenetrating composite hydrogel that would facilitate printability. The produced composite hydrogel showed good structural, morphological, thermal, and textural properties. CMFs with 5% guar gum showing optimal surface properties and rheological properties were printed with the least dimensional errors at 50% infill density, 10 mm/s printing speed, 0.8 mm nozzle diameter, and 0.5 mm layer height. The treatment with borax showed good shape fidelity during 12 h storage. The treated construct also showed considerably increased mechanical properties and antioxidant activities in comparison with the untreated construct. A stable 3D construct suitable for a variety of applications could be produced using CMFs and guar gum-based ink.
3D Aerosol Jet® printing for microstructuring: Advantages and limitations
Authors: Seiti Miriam , Degryse Olivier , Monica Ferraro Rosalba , Giliani Silvia , Bloemen Veerle , Ferraris Eleonora
Published: August 2023

Aerosol Jet® printing (AJ®P) is a direct writing printing technology that deposits functional aerosolized solutions on free-form substrates. Its potential has been widely adopted for two-dimensional (2D) microscale constructs in printed electronics (PE), and it is rapidly growing toward surface structuring and biological interfaces. However, limited research has been devoted to its exploitation as a three-dimensional (3D) printing technique. In this study, we investigated AJ®P capabilities for 3D microstructuring of three inks, as well as their advantages and limitations by employing three proposed 3D AJ®P strategies (continuous jet deposition, layer-by-layer, and point-wise). In particular, 3D microstructures of increasing complexity based on silver nanoparticle (AgNPs)-, poly(3,4-ethylenedioxythiophene)polystyrene sulfonate (PEDOT:PSS)-, and collagen-based inks were investigated at various aspect ratios and resolutions. Biocompatibility assays were also performed to evaluate inks cytotoxicity effects on selected cellular lineages, including neuronal and osteoblast cell lines. Results show the possibility to print not only arrays of micropillars of different aspect ratios (AgNPs-ARs ~ 20, PEDOT:PSS-ARs ~ 4.5, collagen-ARs ~ 2.5), but also dense and complex (yet low reproducible) leaf- or flake-like structures (especially with the AgNPs-based ink), and lattice units (collagen-based ink). Specifically, this study demonstrates that the fabrication of 3D AJ®-printed microstructures is possible only with a specific set of printing parameters, and firmly depends on the ink (co-)solvents fast-drying phenomena during the printing process. Furthermore, the data concerning inks biocompatibility revealed high cytotoxicity levels for the AgNPs-based ink, while low ones for the PEDOT:PSS and the collagen-based inks. In conclusion, the paper provides general guidelines with respect to ink development and print strategies for 3D AJ®P microstructuring, opening its adoption in a vast range of applications in life science (tissue engineering, bioelectronic interfaces), electronics, and micromanufacturing.
The attractiveness of 4D printing in the medical field: Revealing scientific and technological advances in design factors and applications
Authors: Martinez-De-Anda Angelica A. , Rodriguez-Salvador Marisela , Castillo-Valdez Pedro F.
Published: August 2023

Currently, there is an increasing demand in the medical field for low-cost, high-quality products as well as personalized solutions, and different manufacturing methods are being investigated to provide innovative solutions. Four-dimensional (4D) printing is a promising technology that could overcome the challenges associated with the applications of three-dimensional printing in regenerative medicine and biomedical devices. A revolution is expected in this regard, and it is essential to keep abreast of the latest developments. Under this context, the purpose of this paper is to reveal scientific and technological advances of 4D printing in the medical field using a competitive technology intelligence (CTI) methodology. To this end, publications were analyzed from the Scopus database between January 1, 2017, and May 9, 2023. The main trends were identified for both design factors and applications. In the first case, the following were considered: 4D printing methods, external stimuli, materials, mathematical models, and interaction mechanisms. In contrast, in the second case, the applications of 4D printing involved were considered: drug delivery systems, stents, and scaffolds. The obtained design factors results included improvements in mechanical properties of hydrogels by adding magnetic nanoparticles, biopolyurethane, and other materials, the development of cell-friendly bioprinting methods to print cellular structures, and the use of theoretical-experimental approaches to predict shape deformation of structures. While for applications, results included advances in the development of expandable drug delivery systems, fabrication of stents for the treatment of vascular and tracheal stenosis, and the design of scaffolds to treat cartilage defects and bone regeneration. This study provides insights to researchers, academics, and companies involved in research and development as well as innovation that are looking for new solutions to improve health by incorporating breakthrough technologies such as 4D printing.
Rheology-informed hierarchical machine learning model for the prediction of printing resolution in extrusion-based bioprinting
Authors: Oh Dageon , Shirzad Masoud , Chang Kim Min , Chung Eun-Jae , Nam Seung Yun
Published: August 2023

In this study, a rheology-informed hierarchical machine learning (RIHML) model was developed to improve the prediction accuracy of the printing resolution of constructs fabricated by extrusion-based bioprinting. Specifically, the RIHML model, as well as conventional models such as the concentration-dependent model and printing parameter-dependent model, was trained and tested using a small dataset of bioink properties and printing parameters. Interestingly, the results showed that the RIHML model exhibited the lowest error percentage in predicting the printing resolution for different printing parameters such as nozzle velocities and pressures, as well as for different concentrations of the bioink constituents. Besides, the RIHML model could predict the printing resolution with reasonably low errors even when using a new material added to the alginate-based bioink, which is a challenging task for conventional models. Overall, the results indicate that the RIHML model can be a useful tool to predict the printing resolution of extrusion-based bioprinting, and it is versatile and expandable compared to conventional models since the RIHML model can easily generalize and embrace new data.
Pengantar Redaksi dan Daftar Isi
Authors: Team Editorial
Published: August 2023

Pengantar Redaksi
The Influence of Ethnomathematics Based Problem Based Learning (PBL) Model on Gedongsongo Temple Objects on the Creative Thinking Ability of Junior High School Students in View of Self-Confidence
Authors: Suryonegoro Bayu Murti , Hidayah Isti
Published: August 2023

Purpose of the study: In analyzing the relationship between the influence of the Problem-Based Learning (PBL) learning model based on ethnomathematics learning at Gedongsongo Temple on the creative thinking abilities of class IX junior high school students regarding self-confidence.

Methodology: The subjects of this study were Junior high school 1 Jambu students. The research method used is quasi-experimental and posttest-only control design research. Data collection techniques using test and non-test instruments in the form of questionnaires. Quantitative data analysis begins with a prerequisite test using the normality and homogeneity tests. Test the hypothesis using the proportion test and test the regression analysis.

Main Findings: There is a difference in Creative Thinking Ability and a difference in self-confidence which is more increased in applying the problem-based learning model based on Gedongsongo Temple ethnomathematics in class IX junior high school students. Thus, there is a relationship between the influence of the Gedongsongo Temple ethnomathematics problem-based learning model on the creative thinking abilities of class IX junior high school students regarding self-confidence.

Novelty/Originality of this study: The expository model through the teacher-centered approach is believed to be unable to empower students' creative thinking abilities and self-confidence, so creative thinking skills and self-confidence are still low, and students do not play an active role in the process of studying the material in class. Therefore, there needs to be an update using the PBL model with ethnomathematics to improve creative thinking skills.
Ability Analysis of Providing Explanations and Strategies in Learning Science
Authors: Kartina Lia , Nurmeimana Nurmeimana , Abamba Ikechuku , Aswad Amar J.
Published: August 2023

Purpose of the study: This descriptive study aims to analyze science learning based on students' High Order Thinking Skills, which can be seen from the thinking skills of students in junior high schools.

Methodology: This research was conducted at Junior High School State 21 Jambi City using a mixed research method with an explanatory analysis design with two instruments instrument for the quantitative approach and interview sheets for the qualitative approach. The research subjects were 58 students of class VIII. The concept tested is material about lens refraction, divided into ten questions.

Main Findings: Five indicators tested are the ability to provide essential explanations (MPD) and strategies and tactics. After analyzing the student's answers, the average MPD skills were 2.40, and strategy and tactics were 2.48. This critical thinking skill is good because the teacher also provides space for students to be active in learning so that students often ask questions and analyze the material presented in learning science.

Novelty/Originality of this study: The novelty of this study is that analyzing HOTS-based science learning can improve students' critical thinking skills so that students can be active in asking questions and analyzing the material. With necessary thinking skills, students can be more open to differences of opinion, and students can still be objective with the sources of knowledge that they have before.
Rudolf von Ems, Der guote Gêrhart/Der gute Gerhart. Mittelhochdeutsch/Neuhochdeutsch. Hrsg., übersetzt, kommentiert und mit einem Nachwort versehen von Norbert Kössinger und Katharina Philipowski. Stuttgart: Philipp Reclam jun., 2022, 542 S., 4 s/w Abb.
Authors: Classen Albrecht
Published: August 2023

Abstract: Obwohl wir meistens davon ausgehen, dass die höfische Dichtung des Mittelalters relativ konform gestaltet war, sei es, dass Ritter am Hof von König Artus auf Abenteuer losziehen, sei es, dass ein Liebesgeschehen beschrieben wird. Wenn aber ein Kölner
Kaufmann, Gerhart, auftritt, der nach extensiven Handelsreisen bis in den Mittleren Osten auf der Rückreise nach Marokko gelangt und dort mittels seiner Kaufmannsgüter eine norwegische Prinzessin, ihren Hofstaat und eine Gruppe englischer Adliger befreit, was ihm in der Heimat ein
großes Lösegeld einbringen sollte (er fordert dieses niemals ein), geraten wir ins Stutzen. Darüber hinaus erfahren wir, dass Gerhart eine enge Freundschaft mit dem marokkanischen Burggrafen schließt, ohne dass ihre religiösen Unterschiede oder sprachlichen Differenzen
eine Rolle spielen würden. Erstaunlich wirkt ebenfalls, dass Gerhart später die norwegische Prinzessin Erene mit ihrem ursprünglichen Verlobten Willehalm, Prinz von England, verheiratet und, als er mit ihnen nach England reist, dort einen bitteren Bürgerkrieg vermeiden
und Frieden herstellen kann. Der Protagonist trägt das Epithet ‘der Gute’, was Gerhart dem Kaiser Otto dadurch erklärt, indem er seine Lebensgeschichte schildert, Dies bietet Otto eine wichtige Lebenslektion, denn er hatte versucht, mittels des Baus des Magdeburger Doms
sich Gottes Gnade zu ‘erkaufen, worauf ihn ein Engel auf Gerhart verwiesen hatte.
Jenseits der ausgetretenen Pfade: Normüberschreitungen in der höfischen Epik vom späten 12. bis zum frühen 14. Jahrhundert, hrsg. Désirée Mangard und Miriam Strieder. Innsbrucker Beiträge zur Kulturwissenschaft, Germanistische Reihe, 94.
Innsbruck: innsbruck university press, 2021, 301 S., 21 farbl. Abb.
Authors: Classen Albrecht
Published: August 2023

Abstract Auf erstem Blick fühlt man sich sofort vom Bild auf dem Bucheinschlag und auch von dem Titel angezogen, denn zu den zentralen Aufgaben jeglicher Forschungsarbeit gehört genau dieser Ansatz, sich von den ausgetretenen Pfaden zu entfernen und neue Wege einzuschlagen.
In dieser Festschrift für Waltraud Fritsch-Rößler, was hier leider gar nicht angezeigt wird, behandeln die Beiträger aus verschiedenster Sicht die Fragen nach alternativen Perspektiven in der mhd. Epik vom hohen bis zum späten Mittelalter. In sympathischer Weise bemühen
sich einleitend Mangard und Strieder darum, die wichtigsten Publikationen der zu Ehrenden kurz vorzustellen und sie unter das Globalthema zu gruppieren, das dann die einzelnen Autoren individuell weiter verfolgen. Ob aber der Begriff ‘anarchisches Element’ in diesem Kontext wirklich
hilfreich sein mag (13), scheint mir etwas problematisch zu sein. Aber die Untergruppen, 1. wilde Innenwelten auf Abwegen, 2. unbändige Gefühle und Konflikte und 3. wundersame Wesen, sind wirklich vielversprechend, während 4. wagemutige Bearbeitungen, sich eher auf philologische
Aspekte bezieht und mehr technischer Art ist (Kurt Gärtner, zu Hartmanns von Aue Erec).
Rancang Bangun Aplikasi Management System “Digihelp” pada PT. Swamedia Informatika
Authors: Sinaga Arnold Ropen , Pratama Kevin
Published: August 2023

Informasi merupakan suatu tuntutan dalam memenuhi kebutuhan sehingga mendorong untuk membentuk suatu aplikasi sebagai sarana penunjang kebutuhan informasi tersebut. Aplikasi yang relevan dengan hal itu salah satunya adalah digihelp. Masalah yang dihadapi oleh Telkom Corporate University (Telkom Corpu) salah satunya adalah pada sistem manajemen belum mempunyai antarmuka serta front-end website. Aplikasi sistem digihelp ini merupakan solusi dari permasalahan yang ada. Pembangunan suatu sistem informasi yang dapat berjalan seperti apa yang diharapkan dapat menggunakan SDLC (Systems Development Life Cycle atau Systems Life Cycle) yang melalui tahapan: perencanaan, analisa, desain dan yang terakhir adalah tahap implementasi, setelah itu proses uji coba. Pengelolaan juga harus dilakukan sebagai perawatan dari system. Penelitian ini dimulai dengan melakukan perancangan kebutuhan sistem, kemudian membuat desain sistem yang terdiri dari pemilihan typography, system color, button size dan grid & spacing, lalu dilanjutkan dengan design wireframe dan design component yang digunakan dalam aplikasi sampai akhirnya dibuatlah design final dari aplikasi itu yang nantinya digunakan sebagai acuan oleh programmer dalam melakukan pengkodean secara front-end dari aplikasi yang dirancang, dan yang terakhir adalah membuat front-end dari User Interface dengan acuan desain sebelumnya yang telah dibuat.
Tamthilia ya Kiswahili katika Ukuaji na Ustawi Endelevu wa Ujasiriamali Nchini Tanzania: Uchunguzi wa Tamthilia ya Safari ya Chinga (2009) ya Shani Omari
Authors: Masatu Furaha Jumapili
Published: August 2023

Ujasiriamali ni wimbo unaozidi kurindima masikioni mwa wanajamii. Wimbo huu unatokana na changamoto ya fursa funge za ajira miongoni mwa vijana. Tatizo linaonekana kuwa kubwa kwa sababu vijana wengi hawaonekani kuwa na msukumo wa ndani na wa kimazingira wa kujiajiri. Vijana wengi bado wanaamini katika kuajiriwa badala ya kujiajiri ilhali fursa za ajira rasmi wazitakazo ni chache kuliko idadi yao. Serikali na wadau wa maendeleo, wanazidi kukuna vichwa kutafuta ufumbuzi wa changamoto hii ya ajira miongoni mwa vijana. Mojawapo ya mapendekezo ya kutatua changamoto hii, ni kwa serikali na wadau kuwawezesha vijana kujikomboa kifikra kupitia elimu na mazingira rafiki kwa ujasiriamali. Baadhi ya wadau, wanaamini elimu rasmi ya ujasiriamali katika shule ya msingi na sekondari ndiyo suluhu kwa vijana kufikiria kujiajiri. Hata hivyo, kuna hoja kuwa wadau wa elimu wamechelewa sana kuiteua tamthilia ya Safari ya Chinga (2009) ya Shani Omari kuwa tamthilia ya kiada miongoni mwa tamthilia rasmi zinazopaswa kufundishia na kujifunza uhakiki wa fasihi na ujasiriamali katika ngazi ya sekondari na vyuo. Hivyo, makala haya yanawasilisha sehemu ya matokeo ya uchunguzi tulioufanya kuhusiana na maudhui ya tamthilia ya Safari ya Chinga ili kuonesha nafasi adhimu ya Tamthilia ya Kiswahili katika ukuaji na ustawi endelevu wa ujasiriamali nchini Tanzania.
Study on Application of AI Controllers for Speed Control of Motors
Authors: Ketan Kalke  , Dr. Bhumeshwar Patle
Published: August 2023

Building high-performance motor drives is vital for industrial uses. A high-performance motor drive system must be quick in terms of dynamic speed order monitoring and load regulation. The motor controllers can provide system protection by regulating or limiting torque, protecting against overloads, and safeguarding against mistakes. Many motor controllers include logic for managing applications as well as additional features like data recording and data collecting. The purpose is to study various tuning techniques for motor speed controllers using Artificial intelligence. The controllers such as proportional-integral (PI) controller and proportional integral derivative (PID) controller have been considered here. Most frequently used Artificial intelligence (AI) methods such as Artificial Neural Networks (ANN), Fuzzy logic controller (FLC), Genetic Algorithm (GA), Bat Algorithm, Adaptive Tabu Search (ATS), Ant Colony Optimization (ACO), Ziegler and Nichols (ZN) Algorithm are considered by their decision-making capability. In the proposed work a rigorous literature review is done for analyzing the performance of AI-based controllers. This will help other researchers to understand various aspects of the said controllers, particularly the technology involved. In-depth review and application of AI controllers are highlighted using various charts and graphs for easy understanding.

Keywords: AI motor controllers, Fuzzy Logic, PID controller, PI controller, Genetic algorithm, PSO algorithm, Ziegler and Nichols algorithm, Bat algorithm, Adaptive Tabu search algorithm
Design and Development of Indigenous EV Motor Test Rig for Small Capacity Motor Testing
Authors: Sreekumar U.
Published: August 2023

Electric Vehicle is increasing at a faster pace. There is a need for them to meet a variety of reliability requirements. The reliability of the product in the automotive domain is very important as if the product fails it can cause catastrophe. The paper describes the design and development of the Motor Test Rig. The main application of the Electric motor test bench is certification and evaluation testing of motors used in Electric and Hybrid-Electric Vehicles We have designed and developed an indigenous Motor Test Rig for OEM based on the experience we gained in EV motor testing.

Keywords: Failure Rate, MTBF, Automotive, Simulation, Reliability, Indigenous, EV Motor Test Rig, Motor Testing
Functional Safety for Automatic Emergency Braking based on ISO 26262
Authors: Ananda Adhikari  , Aspak Saban  , Shirish Bohora  , Viranchi Shastri
Published: August 2023

The popularity of electronic systems had increased in automobiles. A lot of ECUs, electronics sensors, bus are used in automobile systems which has made the system complex. Safety analysis should be done to ensure functional safety. IEC has introduced the standard, ISO 26262 for safety analysis of electrical/electronic/programmable systems in automobiles to reduce and control systematic faults. ISO 26262 give guidelines to define and follow the techniques strategically for the entire product life cycle of the vehicle. It does not explain how functional safety is done but it will guide us throughout the process. In this paper, we have analysed the Automatic Emergency Braking system as per the ISO 26262 guidelines. AEB is a significantly important active safety system which relies on electronic sensors, ECU and electronic actuators. The proper functioning of these electronic components could save the hazard from happening. We have determined the ASIL level, we determine safety goal and safety requirement, Fault Tree Analysis (FTA), Failure mode and Effect analysis. Also, we performed an HW safety analysis.

Keywords: Electronic Sensors, functional safety, ISO 26262, Automatic Emergency Braking, Medini Analyze, Fault Tree analysis (FTA), Electro-Hydraulic Braking System, Failure Mode and Effect Analysis, Model-Based Safety Analysis, Safety Goals, HARA, FTA
Study of Effective Powertrain Sizing for Electric Vehicles
Authors: Siddharth R Gandhi  , Abhijeet Chavan
Published: August 2023

Rapid growth of electric vehicles technology and its efficiency management techniques has led to dramatic rise in the necessity for effective sizing of powertrain components. The recent market need for this technology is the optimized powertrain design to encourage further evolvement. In present study, thorough calculations involved in the powertrain sizing through various assessments are emphasized. Forces, Power, Energy, Motor and Battery Pack calculations are derived along with discharge rate and battery usage time. Effective powertrain components capacitive size is calculated for an estimated vehicle performance which can eventually assist in the optimal vehicle design which helped in range extension.

Keywords: Electric vehicles, Powertrain design, Battery Pack calculations, vehicle design, hybridization, Hybrid vehicles, fuel powered vehicles, Electrical Drive system, PHEVs, FEVs, fuel cells
Failure Analysis and Product Improvement for Hypoid Gearset of Rear Axle
Authors: Prasanna Venkatesan R.  , Sundarayya V.  , Yoganand R. D.
Published: August 2023

The current market trend shows that LCV vehicle sales are in increasing phase and more demands are expected by customers in which the Vehicle manufacturers should meet their requirements and applicate the right product accordingly. This paper will briefly explain about the investigation results of Ring gear premature failure in LCV Rear axles. The rear axle is a Structural member which should meet both Fatigue and impact strength requirements; thereby axle can meet Customer requirements which are used to experiencing different duty cycles and load patterns. The scope of this paper explains about detailed Investigation which has been taken like Field Study, Failure Part’s Strip down analysis and Fracture analysis. In addition to that Failure simulation analysis was also performed through CAE verification and Vehicle level Validation for correlation study. Based on the Investigation results, Gear design modification proposals have been taken and underwent the CAE analysis to finalize opt design for development. Post development of new gear set, Vehicle level validation has been carried out and found no issues in Field operating condition.
Keywords: LCV vehicles, CAE Analysis, Hypoid Gearset, Ring Gear, Failure analysis, Fracture Analysis, Strip down analysis, Failure, simulation analysis
MANAGEMENT OF THE ONBOARDING PROCESS INFORMATION SUPPORT OF IT SPECIALISTS USING RPA TECHNOLOGIES
Authors:   Ufa University of Science and Technology, Dron Е.А. , Pavlovich Т.V. ,   Russian Technological University MIREA
Published: August 2023

Enterprises have recently begun to hold public conferences, which consider the proposed development of a software solution for onboarding new professionals. Therefore, when large companies onboard new young specialists their HR-managers need to have high-quality, fast and effective onboarding system. To implement an onboarding system based on distance learning, a new employee will have access to the company's courses. A new employee uses this system and takes basic courses aimed to enhance professional competencies, such as teamwork, customer focus, critical thinking, presentation and communication skills and etc. A new employee takes courses to deep study of his professional area. These courses are related to the study of the business-process, interactions with the user, the design of enterprise systems. By the end of the study an employee will have theoretical knowledge, backed up by tests and assignments in the courses, as well as handouts from the courses.
Aplicación móvil para estimar el porcentaje de deserción escolar usando minería de datos
Authors: Ruiz Ledesma Elena Fabiola , Chavarría Báez Lorena , Veliz Martínez Juan Carlos
Published: August 2023

Este artículo reporta el desarrollo de una aplicación móvil, haciendo uso de técnicas de minería de datos, para determinar un modelo de reglas de decisión e incluirlas en la aplicación usando JSON. La metodología utilizada para el desarrollo fue CRISP-DM. Para el proceso de minería de datos se utilizó la información de 949 estudiantes de una institución pública de México, considerando 7 variables. La aplicación generada permite estimar la probabilidad que tiene un estudiante de no culminar sus estudios, para poder actuar en consecuencia, buscando estrategias que apoyen la mejora de las condiciones de los estudiantes, según los factores detectados.
Dysregulated microRNAs as a biomarker for diagnosis and prognosis of hepatitis B virus-associated hepatocellular carcinoma
Authors: Zhang Ming-He , Yuan Yu-Feng , Liu Li-Juan , Wei Yu-Xin , Yin Wan-Yue , Zheng Lan-Zhuo-Yin , Tang Ying-Ying , Lv Zhao , Zhu Fan
Published: August 2023

Hepatocellular carcinoma (HCC) is a malignancy with a high incidence and fatality rate worldwide. Hepatitis B virus (HBV) infection is one of the most important risk factors for its occurrence and development. Early detection of HBV-associated HCC (HBV-HCC) can improve clinical decision-making and patient outcomes. Biomarkers are extremely helpful, not only for early diagnosis, but also for the development of therapeutics. MicroRNAs (miRNAs), a subset of non-coding RNAs approximately 22 nucleotides in length, have increasingly attracted scientists’ attention due to their potential utility as biomarkers for cancer detection and therapy. HBV profoundly impacts the expression of miRNAs potentially involved in the development of hepatocarcinogenesis. In this review, we summarize the current progress on the role of miRNAs in the diagnosis and treatment of HBV-HCC. From a molecular standpoint, we discuss the mechanism by which HBV regulates miRNAs and investigate the exact effect of miRNAs on the promotion of HCC. In the near future, miRNA-based diagnostic, prognostic, and therapeutic applications will make their way into the clinical routine.
Inherited CHEK2 p.H371Y mutation in solitary rectal ulcer syndrome among familial patients: A case report
Authors: He Cheng-Cheng , Wang Shan-Ping , Zhou Pei-Rong , Li Zhi-Jun , Li Na , Li Ming-Song
Published: August 2023

Hepatocellular carcinoma (HCC) is a malignancy with a high incidence and fatality rate worldwide. Hepatitis B virus (HBV) infection is one of the most important risk factors for its occurrence and development. Early detection of HBV-associated HCC (HBV-HCC) can improve clinical decision-making and patient outcomes. Biomarkers are extremely helpful, not only for early diagnosis, but also for the development of therapeutics. MicroRNAs (miRNAs), a subset of non-coding RNAs approximately 22 nucleotides in length, have increasingly attracted scientists’ attention due to their potential utility as biomarkers for cancer detection and therapy. HBV profoundly impacts the expression of miRNAs potentially involved in the development of hepatocarcinogenesis. In this review, we summarize the current progress on the role of miRNAs in the diagnosis and treatment of HBV-HCC. From a molecular standpoint, we discuss the mechanism by which HBV regulates miRNAs and investigate the exact effect of miRNAs on the promotion of HCC. In the near future, miRNA-based diagnostic, prognostic, and therapeutic applications will make their way into the clinical routine.
Penyusunan dan Pelaporan Anggaran Pembangunan pada Dinas Pekerjaan Umum dan Penataan Ruang Kota Bogor
Authors: Melati Citra , Suwarno Suwarno
Published: August 2023

Anggaran merupakan rencana kegiatan yang dilaksanakan oleh suatu organisasi ataupun perorangan untuk masa yang akan datang dalam jangka waktu tertentu dan dinyatakan dalam satuan uang. Penyusunan anggaran dilakukan untuk menyempurnakan rencana yang telah disusun karena dengan anggaran menjadi lebih jelas dan nyata terlihat.

            Tujuan Riset ini adalah untuk mengevaluasi anggaran pembangunan yang dilakukan secara berkala dan sistematis. Evaluasi ini dilakukan untuk mengetahui proses penyusunan dan pelaporan anggaran pembangunan pada Dinas Pekerjaan Umum dan Penataan Ruang (PUPR) Kota Bogor apakah telah sesuai dengan Peraturan Perundang-undangan yang berlaku. Evaluasi dilakukan dengan membandingkan antara praktik penyusunan dan pelaporan anggaran dengan ketentuan penyusunan dan pelaporan anggaran dalam Peraturan Perundang-Undangan. Hasil Riset ini menunjukkan bahwa penyusunan dan pelaporan anggaran pembangunan pada Dinas Pekerjaan umum dan penataan Ruang (PUPR) Kota Bogor telah sesuai dengan Kepmendagri Nomor 050-3708 Tahun 2020 Tentang Hasil Verifikasi dan Validasi Pemutakhiran Klasifikasi, Kodefikasi, dan Nomenklatur Perencanaan Pembangunan dan Keuangan Daerah.

           

Keywords : Penyusunan dan Pelaporan Anggaran
Tinjauan Atas Kepuasan Pelanggan BPJS Kesehatan Di Rumah Sakit Umum Daerah Kota Bogor
Authors: Yusdira Ade , Rezkya Inggrid
Published: August 2023

Kepuasan pelanggan merupakan faktor terpenting dalam berbagai kegiatan bisnis pada perusahaan. Kepuasan pelanggan adalah tanggapan konsumen terhadap evaluasi ketidak sesuaian yang dirasakan antara harapan yang sebelumnya dengan kinerja produk yang dirasakan. Dengan terpuaskannya keinginan dan kebutuhan para pelanggan, maka hal tersebut memiliki dampak yang positif bagi perusahaan. Tujuan penelitian ini adalah untuk 1.) Mengetahui bagaimana kepuasan pelanggan BPJS Kesehatan yang berada di Rumah Sakit Umum Daerah Kota Bogor. 2.) Untuk mengetahui hambatan pelayanan BPJS Kesehatan di RSUD Kota Bogor. 3) Untuk mengetahui upaya menangani hambatan pelayanan BPJS Kesehatan di RSUD Kota Bogor. Evaluasi dilakukan untuk mengetahui pelayanan BPJS Kesehatan terhadap pasien di Rumah Sakit Umum Daerah Kota Bogor. Hasil penelitian ini menunjukan bahwa Rumah Sakit Umum Daerah Kota Bogor telah mengupayakan pelayanan untuk pelanggan BPJS Kesehatan dengan cukup baik. Manfaat pelayanan yang cukup baik dapat dirasakan oleh pelanggan BPJS Kesehatan, sehingga memberikan kepuasan pada pelanggan di RSUD Kota Bogor.

 

Keywords : kepuasan pelanggan, BPJS Kesehatan, Rumah Sakit Umum Daerah Kota Bogor
Proses Perhitungan Harga Pokok Produksi Berdasarkan Full Costing Sebagai Dasar Dalam Menentukan Harga Jual Pada CV Albaik Herbal Indonesia
Authors: Amanda Shanya , Jasmadeti Jasmadeti
Published: August 2023

Penetapan biaya produksi sangat penting karena meningkatkan persaingan antar perusahaan dalam menghasilkan produk yang berkualitas dengan harga yang kompetitif. Perhitungan harga pokok produksi (HPP) merupakan hal yang penting untuk diperhatikan dalam menentukan harga jual produk. Perhitungan HPP yang tepat dan akurat merupakan hal yang harus dilakukan oleh setiap perusahaan, karena tanpa adanya perhitungan HPP yang tepat dan akurat, perusahaan manufaktur yang bersangkutan akan mengalami masalah dalam menentukan harga jual suatu produk. Tujuan penelitian ini adalah untuk menganalisis bagaimana pengalokasian dan perhitungan harga pokok produksi dalam menentukan harga jual kapsul pelangsing dengan metode perusahaan dan metode full costing. Hasil penelitian ini menunjukan terdapat kelemahan dalam perhitungan harga pokok produksi dalam menentukan harga jual perusahaan yaitu kalkulasi harga jual yang dilakukan perusahaan lebih rendah dari pada harga jual setelah dievaluasi. Menurut perusahaan harga jual kapsul pelangsing sebesar Rp 29.334/pcs, sedangkan harga jual dengan metode full costing sebesar Rp 30.014/pcs, hal ini disebabkan karena perusahaan tidak membebankan biaya bahan baku seperti gas, biaya air, dan biaya tenaga kerja tidak langsung. Metode penetapan full costing adalah suatu metode penentuan harga pokok produksi yang menghitung semua unsur dari biaya produksi yang terdiri dari biaya bahan baku, tenaga kerja langsung, tenaga kerja tidak langsung, biaya overhead pabrik, baik biaya tetap maupun biaya variabel. Harga jual dapat diperoleh dari harga pokok produksi ditambah keuntungan yang diharapkan. Hasil penelitian menyatakan bahwa perhitungan harga pokok produksi terdapat selisih yang mempengaruhi harga jual.

 

Kata kunci : harga pokok produksi, full costing, harga jual.
Tinjauan Atas Layanan Mobile Banking Maslahah Pada Bank BJB Syariah
Authors: Apandi Saftalina Meilani , Suardy Weman , Purnama Denta
Published: August 2023

Mobile Maslahah Mobile maslahah merupakan layanan dari Bank Bjb Syariah  memberikan suatu pelayanan e-banking maupun delivery channel berdasarkan prinsip syariah yang bisa di unduh oleh nasabah melalui AppsStore ataupun GooglePlaystore yang ada pada smartphone nasabah. Yang memudahkan nasabah dalam bertransaksi  dimana saja selama 24 jam dengan jaringkan komunikasi data 3G/GPRS/EVDO/WiFi. Tujuan dari penelitian yang dilakukan oleh penulis yaitu Untuk mengetahui layanan system mobile banking maslahah pada Bank BJB Syariah, Untuk mengetahui apa saja hambatan dalam layanan Mobile banking maslahah pada Bank BJB Syariah, Untuk mengetahui bagaimana upaya menangani hambatan dalam layanan Mobile banking maslahah pada Bank BJB Syariah. Melalui penelitian ini, penulis mendapatkan hasil bahwa untuk mengukur bagaimana layanan mobile banking maslahah ini dengan menggunakan 5 dimensi kualitas pelayanan yaitu Reability, Assurance, Tangible, Empathy, Responsive dan layanan Mobile banking maslahah ini telah mencakup ke 5 dimensi kualitas pelayanan tersebut.

Kata kunci : Kualitas pelayanan
Sistem Informasi Akuntansi Dalam Kaitannya Dengan Laporan Biaya Produksi Pada Perusahaan CV Surya Pratama Gemilang
Authors: Iriyadi Iriyadi , Pamungkas Bambang , Gunawan Lussar Gerrycia
Published: August 2023

Development of competitive businesses have triggered changes in the various methods of business management to streamline labor costs, overhead costs and raw material costs in improving product quality. Manufacturing companies are in a period of dynamic transformation that requires the manufacturers to always expand its business to survive and have strong competitiveness in addition to the company must have a strategy for its business organization, strategies must be developed by the company in addition to developing the company's products also must develop the data processing. Hopefully, by the system of all the activities of the company can be run according to plan and to minimize deviations or errors that occur which could harm the company. Object of research chosen by the authors is the company CV Surya Pratama Gemilang, a medium-sized manufacturing company that produces a variety of bacterial decomposition and laboratory equipment. The company has a systematic record system and computerized production and there are some systems that are still made manually as demandfor raw materials from the production to the warehouse with a wane sometimes only just though the procedure had to use a memo for taking raw materials from the warehouse. In doing production company CV Surya Pratama Gemilang processing raw materials into finished products based on processes that make the production process according to the requirement or determination of the bam, so when the warehouse inventory is less than the policysetting in the warehouse, the company started production to meet the needs of the provisions in the warehouse. From the nature of the production process suitable production cost calculation is based on the cost method (Process Costing).

Keywords: Accounting Information Systems, report production costs, Cost Based Process
Theory of change for implementing matrix support in mental health
Authors: Treichel Carlos Alberto dos Santos , Silva Michelle Chanchetti , Presotto Rodrigo Fernando , Leme Kaleb Eliel Ferreira , Reis Maria Fernanda Lirani dos , Amorim Sulamita Gonzaga Silva , Lourencetti Ana Laura Salomé , Saidel Maria Giovana Borges , Campos Rosana Teresa Onocko
Published: August 2023

Objective: To describe the process of development of the theory of change for the implementation of Matrix Support in a medium-sized municipality in São Paulo and to reflect on the contributions of this approach to the planning and evaluation of this intervention, considering the potentialities and challenges from its execution remotely.
Methods

Qualitative study performed through participatory workshops and construction of narratives with workers and managers of the Psychosocial Care Network following the recommendations of a guide for the development of the theory of change in complex interventions.

Results: The implementation of Matrix Support configures one of the three distal results that culminate in the possibility of establishing the logic of shared care related to the activation of intersectoral network and the implementation of a Continuing Education Committee. External components that should be guaranteed by the organizational context for the effective achievement of some intermediate and long-term results were also recognized.

Conclusion: The development of the theory of change was effective in delimiting objectives and implementation components from the perspective of the actors involved, establishing indicators for its monitoring and evaluation based on context conditions, and enabling the direction of workers’ efforts towards its consolidation.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway. Neural Regen Res. 2023 May;18(5)1067–1075
Authors: Gakhar Diksha
Published: August 2023

Despite the fact that a number of therapeutic modalities have shown promise in the treatment of spinal cord injury (SCI), focusing solely on one aspect of recovery will not lead to successful and useful regeneration in people. The current study targets an integrated approach of neuroprotection and rehabilitation strategies to treat spinal cord injury, increasing nerve regeneration and functional recovery through functional sensorimotor training and cell transplantation. Sun et al., 2022 investigated the synergistic effect of exercise training and bone marrow mesenchymal stem cell transplantation which could promote active recovery in a mice model of thoracic contusive spinal cord injury.
DOES GREEN FINANCE SUPPORT TO REDUCE THE INVESTMENT SENSITIVITY OF ENVIRONMENTAL FIRMS?
Authors: Habib Ashfaq , Khan Muhammad Asif , Oláh Judit
Published: August 2023

This study aims to examine the financing cash flow sensitivity into the firm investment of Environment Sensitive Firms (ESFs). To improve the robustness of our analysis, we implement cluster regression to analyze the 300- firms listed on Shenzhen Stock Exchange. The findings of this study indicate that high-ESFs have more financing cash flow volatility in firm investment than low-ESFs. The firms can reduce this volatility by integrating green finance with their financing cash flows. Green finance helps to implement sustainable investment practices and reduces investment volatility by providing the solution to societal issues. It also assists to generate stable cash flows, lower investment risk, and a better governance structure.
THE SUSTAINABLE CYCLE BETWEEN LEAN PRODUCTION AND AUDITING PRACTICES AND ITS EFFICIENCY IN IMPROVING SUPPLIER RELATIONSHIPS AND GREEN SUPPLY CHAINS
Authors: Xiang Huang , Chen Ping-Kuo , Zhang Guodao
Published: August 2023

This study explores why a sustainable cycle is induced when manufacturers implement auditing in combination with lean production. Furthermore, it verifies whether this sustainable cycle enhances process integration and risk resilience, thereby allowing the manufacturer to build strong cooperation with suppliers, which further produces a positive effect on the green supply chain. Sociotechnical systems theory is our theoretical basis, and calculating Spearman’s rank correlation coefficient and estimating PLS regressions are the main methods used. The results show that the implementation of auditing induces two driving forces: internal responsibility and the ability to respond to emergencies. These two forces drive suppliers to actively and positively cooperate with lean practices to ensure that the effect of those practices is strengthened. Moreover, stronger lean practices also produce two feedback forces – expanded tolerance for auditing and expanded acceptance of auditing interventions – that strengthen auditing practices. As a result, the mutually continuous strengthening of lean production and auditing practices is produced, which further becomes a sustainable cycle. This cycle can continue to enhance process integration and increase risk resilience, build strong cooperation with suppliers, and improve the green supply chain.
What’s the Difference? The Potential for Convolutional Neural Networks for Transient Detection without Template Subtraction
Authors: Acero-Cuellar Tatiana , Bianco Federica , Dobler Gregory , Sako Masao , Qu Helen ,   The LSST Dark Energy Science Collaboration
Published: August 2023

We present a study of the potential for convolutional neural networks (CNNs) to enable separation of astrophysical transients from image artifacts, a task known as “real–bogus” classification, without requiring a template-subtracted (or difference) image, which requires a computationally expensive process to generate, involving image matching on small spatial scales in large volumes of data. Using data from the Dark Energy Survey, we explore the use of CNNs to (1) automate the real–bogus classification and (2) reduce the computational costs of transient discovery. We compare the efficiency of two CNNs with similar architectures, one that uses “image triplets” (templates, search, and difference image) and one that takes as input the template and search only. We measure the decrease in efficiency associated with the loss of information in input, finding that the testing accuracy is reduced from ∼96% to ∼91.1%. We further investigate how the latter model learns the required information from the template and search by exploring the saliency maps. Our work (1) confirms that CNNs are excellent models for real–bogus classification that rely exclusively on the imaging data and require no feature engineering task and (2) demonstrates that high-accuracy (>90%) models can be built without the need to construct difference images, but some accuracy is lost. Because, once trained, neural networks can generate predictions at minimal computational costs, we argue that future implementations of this methodology could dramatically reduce the computational costs in the detection of transients in synoptic surveys like Rubin Observatory's Legacy Survey of Space and Time by bypassing the difference image analysis entirely.