bluuebunny/crossref_metadata_2025 huggingface dataset:
Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regions
Authors: Li Qingqin S. , Sun Yu , Wang Tania
Published: October 2020

Background

Growing evidence shows that epigenetic modifications play a role in Alzheimer’s disease (AD). We performed an epigenome-wide association study (EWAS) to evaluate the DNA methylation differences using postmortem superior temporal gyrus (STG) and inferior frontal gyrus (IFG) samples.

Results

Samples from 72 AD patients and 62 age-matched cognitively normal controls were assayed using Illumina© Infinium MethylationEPIC BeadChip. Five and 14 differentially methylated positions (DMPs) associated with pathology (i.e., Braak stage) with p value less than Bonferroni correction threshold of 6.79 × 10–8 in the STG and IFG were identified, respectively. These cytosine–phosphate–guanine (CpG) sites included promoter associated cg26263477 annotated to ABCA7 in the STG (p = 1.21 × 10–11), and cg14058329 annotated to the HOXA5/HOXA3/HOXA-AS3 gene cluster (p = 1.62 × 10–9) and cg09448088 (p = 3.95 × 10–9) annotated to MCF2L in the IFG. These genes were previously reported to harbor DMPs and/or differentially methylated regions (DMRs). Previously reported DMPs annotated to RMGA, GNG7, HOXA3, GPR56, SPG7, PCNT, RP11-961A15.1, MCF2L, RHBDF2, ANK1, PCNT, TPRG1, and RASGEF1C were replicated (p < 0.0001). One hundred twenty-one and 173 DMRs associated with pathology in the STG and IFG, respectively, were additionally identified. Of these, DMRs annotated to 30 unique genes were also identified as significant DMRs in the same brain region in a recent meta-analysis, while additional DMRs annotated to 12 genes were reported as DMRs in a different brain region or in a cross-cortex meta-analysis. The significant DMRs were enriched in promoters, CpG islands, and exons in the genome. Gene set enrichment analysis of DMPs and DMRs showed that gene sets involved in neuroinflammation (e.g., microglia differentiation), neurogenesis, and cognition were enriched (false discovery rate (FDR) < 0.05).

Conclusions

Twenty-two DMPs and 30 DMRs associated with pathology were replicated, and novel DMPs and DMRs were discovered.
Serial blockface SEM suggests that stem cells may participate in adult notochord growth in an invertebrate chordate, the Bahamas lancelet
Authors: Holland Nicholas D. , Somorjai Ildiko M. L.
Published: October 2020

Background

The cellular basis of adult growth in cephalochordates (lancelets or amphioxus) has received little attention. Lancelets and their constituent organs grow slowly but continuously during adult life. Here, we consider whether this slow organ growth involves tissue-specific stem cells. Specifically, we focus on the cell populations in the notochord of an adult lancelet and use serial blockface scanning electron microscopy (SBSEM) to reconstruct the three-dimensional fine structure of all the cells in a tissue volume considerably larger than normally imaged with this technique.

Results

In the notochordal region studied, we identified 10 cells with stem cell-like morphology at the posterior tip of the organ, 160 progenitor (Müller) cells arranged along its surface, and 385 highly differentiated lamellar cells constituting its core. Each cell type could clearly be distinguished on the basis of cytoplasmic density and overall cell shape. Moreover, because of the large sample size, transitions between cell types were obvious.

Conclusions

For the notochord of adult lancelets, a reasonable interpretation of our data indicates growth of the organ is based on stem cells that self-renew and also give rise to progenitor cells that, in turn, differentiate into lamellar cells. Our discussion compares the cellular basis of adult notochord growth among chordates in general. In the vertebrates, several studies implied that proliferating cells (chordoblasts) in the cortex of the organ might be stem cells. However, we think it is more likely that such cells actually constitute a progenitor population downstream from and maintained by inconspicuous stem cells. We venture to suggest that careful searches should find stem cells in the adult notochords of many vertebrates, although possibly not in the notochordal vestiges (nucleus pulposus regions) of mammals, where the presence of endogenous proliferating cells remains controversial.
An ovarian torsion in a 2-year-old girl: a case report
Authors: De Silva Mawanane Hewa Aruna Devapriya , Kolombage Padmini , Kasthuri Sembakutti
Published: October 2020

Background

Abdominal pain is one of the most common complaints by patients in the emergency department. Diarrhea, constipation, and urinary tract infection are the commonest etiologies among these patients, but there are surgical emergencies, such as appendicitis and volvulus of the intestine, which are less common. Torsion of the ovary is rarer than all of the above conditions. Ovarian torsion occurs following the twisting of the ovary on its ligamentous attachment, possibly with a cyst, leading to the impediment of blood flow. Prompt diagnosis with a high clinical suspicion is essential to salvage the ovaries and to prevent complications, including death.

Case presentation

Here, we present a case of ovarian torsion in a 2-year-old Sri Lankan girl who presented with nonspecific abdominal symptoms after being symptomatically treated twice by her general practitioners for 3 days. Following biochemical and radiological investigations, she was diagnosed with a twisted necrotic ovarian torsion and underwent laparoscopic right-sided oophorectomy.

Conclusions

Finding the etiology of a child with abdominal pain is challenging, especially because of the limited history, examination findings, the difficulty in carrying out radiological investigations, and the poor specificity of the results compared with adults. This is a case presentation and a brief discussion about the dilemmas and difficulties in the diagnosis and treatment of ovarian torsion in young children.
Analysis of the microRNA expression profiles of chicken dendritic cells in response to H9N2 avian influenza virus infection
Authors: Yang Jing , Huang Xinmei , Liu Yuzhuo , Zhao Dongmin , Han Kaikai , Zhang Lijiao , Li Yin , Liu Qingtao
Published: October 2020

MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression profiles in chicken dendritic cells infected with H9N2 avian influenza virus (AIV). A total of 66 known and 36 novel miRNAs were differently expressed upon H9N2 infection, including 72 up-regulated and 30 down-regulated miRNAs. Functional analysis showed that the predicted targets of these miRNAs were significantly enriched in several pathways including endocytosis, notch, lysosome, p53, RIG-I-like and NOD-like receptor signaling pathways. These data provide valuable information for further investigating the roles of miRNA in AIV pathogenesis and host defense response.
Robust widely linear beamforming using estimation of extended covariance matrix and steering vector
Authors: Meng Zhen , Zhou Weidong , Gazor Saeed
Published: October 2020

The distribution of the received signals in many array processing applications is noncircular. Although optimal widely linear beamformer (WLB) can provide the best performance for noncircular received signals, its performance degrades severely under model mismatches in practical applications. As a remedy, we propose a robust WLB by using precise reconstruction of extended interference-plus-noise covariance matrix (EINCM) and low-complexity estimation of extended desired signal steering vector (EDSSV). We propose to first determine the steering vectors, powers, and noncircularity coefficients of all signals and the noise power. In contrast to the previous reconstruction methods using the integration over a wide angular sector, we reconstruct the interference-plus-noise covariance matrix (INCM) and the pseudo INCM accurately according to their definitions. By using INCM and pseudo INCM, we can precisely reconstruct the EINCM. We propose to estimate the EDSSV by intersecting two extended subspaces, which are respectively formed by eigendecomposing the extended sample covariance matrix and the extended desired signal covariance matrix. Unlike the convex optimization methods, the proposed EDSSV estimation does not require any optimization programming and yields a solution with closed expression in low computational complexity. Simulation results show that the proposed robust WLB provides near optimal performance under several model mismatch cases.
Dynamic properties of a discrete population model with diffusion
Authors: Li Ming-Shan , Zhou Xiao-Liang , Xu Jiang-Ming
Published: October 2020

We study the dynamical properties of a discrete population model with diffusion. We survey the transcritical, pitchfork, and flip bifurcations of nonhyperbolic fixed points by using the center manifold theorem. For the degenerate fixed point with eigenvalues ±1 of the model, we obtain the normal form of the mapping by using the coordinate transformation. Then we give an approximating system of the normal form via an approximation by a flow. We give the local behavior near a degenerate equilibrium of the vector field by the blowup technique. By the conjugacy between the reflection of time-one mapping of a vector field and the model we obtain the stability and qualitative structures near the degenerate fixed point of the model. Finally, we carry out a numerical simulation to illustrate the analytical results of the model.
An efficient finite element method and error analysis for eigenvalue problem of Schrödinger equation with an inverse square potential on spherical domain
Authors: Sui Yubing , Zhang Donghao , Cao Junying , Zhang Jun
Published: October 2020

We provide an effective finite element method to solve the Schrödinger eigenvalue problem with an inverse potential on a spherical domain. To overcome the difficulties caused by the singularities of coefficients, we introduce spherical coordinate transformation and transfer the singularities from the interior of the domain to its boundary. Then by using orthogonal properties of spherical harmonic functions and variable separation technique we transform the original problem into a series of one-dimensional eigenvalue problems. We further introduce some suitable Sobolev spaces and derive the weak form and an efficient discrete scheme. Combining with the spectral theory of Babuška and Osborn for self-adjoint positive definite eigenvalue problems, we obtain error estimates of approximation eigenvalues and eigenvectors. Finally, we provide some numerical examples to show the efficiency and accuracy of the algorithm.
Positive solutions of a discrete second-order boundary value problems with fully nonlinear term
Authors: Jin Liyun , Luo Hua
Published: October 2020

In this paper, we mainly consider a kind of discrete second-order boundary value problem with fully nonlinear term. By using the fixed-point index theory, we obtain some existence results of positive solutions of this kind of problems. Instead of the upper and lower limits condition onf, we may only impose some weaker conditions onf.
A priori bounds of the solution of a one point IBVP for a singular fractional evolution equation
Authors: Mesloub Said , Gadain Hassan Eltayeb
Published: October 2020

A priori bounds constitute a crucial and powerful tool in the investigation of initial boundary value problems for linear and nonlinear fractional and integer order differential equations in bounded domains. We present herein a collection of a priori estimates of the solution for an initial boundary value problem for a singular fractional evolution equation (generalized time-fractional wave equation) with mass absorption. The Riemann–Liouville derivative is employed. Results of uniqueness and dependence of the solution upon the data were obtained in two cases, the damped and the undamped case. The uniqueness and continuous dependence (stability of solution) of the solution follows from the obtained a priori estimates in fractional Sobolev spaces. These spaces give what are called weak solutions to our partial differential equations (they are based on the notion of the weak derivatives). The method of energy inequalities is used to obtain different a priori estimates.
TSME: a trust-based security scheme for message exchange in vehicular Ad hoc networks
Authors: Abassi Ryma , Ben Chehida Douss Aida , Sauveron Damien
Published: October 2020

A Vehicular Ad hoc NETwork (VANET) is a self-organized network formed by connected vehicles, which allows the exchange of useful traffic information in a timely manner. In such a context, evaluating the reliability of transmissions is vital. Trust can be used to promote such healthy collaboration. In fact, trust enables collaborating vehicles to counter uncertainty and suspicion by establishing trustworthy relationships. The main contribution of this paper is the proposition of a trust-based security scheme for message exchange in a VANET called TSME. Because of VANET characteristics, including dynamicity and high speed, we first proposed a VANET Grouping Algorithm (VGA); a suitable clustering algorithm organizing the network into groups with elected Group-Heads. Second, built on the VGA, we defined our trust management scheme dealing with vehicles’ reputations. Finally, we proposed a formal specification of the scheme using an inference system, and conducted a formal validation to assess its completeness and soundness rather than conducting simulations where some potentially rare conflicting or malfunctioning situations might not be detected. Soundness was proven by showing that there were no conflicts in our scheme, and completeness was established by assessing that all potential situations could be handled. The results obtained showed that our scheme for evaluating the veracity of exchanged messages is formally sound and complete.
Assessment of HY-2A GM data by deriving the gravity field and bathymetry over the Gulf of Guinea
Authors: Wan Xiaoyun , Annan Richard Fiifi , Wang Wenbin
Published: October 2020

Nine cycles of Haiyang-2A (HY-2A) IGDR (Interim Geophysical Data Record) data are used to derive gravity products over the Gulf of Guinea (15° W–5° E, 4° S–4° N). Firstly, the sea surface heights (SSH) and vertical deflections are derived and their precisions are evaluated. The comparison results show that the east component of vertical deflections has a poorer precision than the north component by 4.15 times. A theoretical proof was given to explain this point according to the error propagation rule. Gravity anomalies are then derived from vertical deflections using the remove–restore method. The precision of the derived HY-2A gravity anomalies is evaluated with SIO, DTU13, EGM2008, EIGEN-6C4 products. The results showed that the differences between HY-2A-derived gravity anomalies and these models have mean values larger than 0.5 mGal and std values around 7.0–7.3 mGal. In order to improve the precision, an improved new version of gravity anomalies was derived by assigning a small weight to the east component of vertical deflections, since the precision of which is poorer than the north component. Comparison with the initial model showed that the precision of the new gravity anomalies is an improvement of the initial model by approximately two times. When compared with EGM2008, EIGEN-6C4, SIOv28 and DTU13, the mean values of the differences are close to zero and standard deviation of the differences are around 2.7–3.0 mGal. The improved gravity anomalies were used to invert the bathymetry of the region using the gravity-geologic method. The modeled bathymetry compared well with a previous bathymetric study by the authors that used DTU13 gravity anomalies. It also performed well against ETOPO1 and SRTM15+V2; with difference means, standard deviations and correlation coefficients of 26.67 m, 183.09 m, 0.9562; and 12.26 m, 174.55 m, 0.9590, respectively. This implies that SSH data from HY-2A are geophysically reliable; and hence, can be incorporated with SSH data from other satellite altimeters.
Efficacy of Treatments for Polycystic Ovarian Syndrome Management in Adolescents
Authors: Al Khalifah Reem A , Florez Ivan D , Zoratti Michael J , Dennis Brittany , Thabane Lehana , Bassilious Ereny
Published: October 2020

Limited evidence on treatment options for polycystic ovarian syndrome (PCOS) has led to considerable variation in health care practices. We aimed to compare the effects of metformin and/or oral contraceptive pills (OCP) in combination with pioglitazone, spironolactone, flutamide, and lifestyle interventions among adolescents aged 11 to 19 years with PCOS. Literature searches were performed in Medline, Embase, and the Cochrane Central Register of Controlled Trials from database inception through December 2018, with no language restriction. Two reviewers screened titles and abstracts, assessed full text eligibility, and extracted information from eligible trials. Evidence was synthesized through network meta-analyses (NMA) using a Bayesian random-effects approach. We identified 37 randomized controlled trials, in which 2400 patients were randomized. NMA showed no statistically important difference among all interventions to improve menstrual regulation or body mass index. Moderate-quality evidence showed hirsutism scores were reduced by multiple interventions that included single and combination medications namely; lifestyle intervention, metformin, OCP, spironolactone, pioglitazone, metformin-OCP, metformin-spironolactone, and metformin-flutamide against placebo. Moderate-quality evidence showed OCP results in more dysglycemia compared to metformin (odds ratio, 2.98; 95% credible interval, 1.02-8.96), no intervention resulted in dysglycemia reduction. In conclusion, metformin and OCP as monotherapy or in combination with other interventions compared with placebo can reduce hirsutism scores, but none of these medications lead to effective menstrual cycle regulation or weight reduction. However, the use of OCP leads to worse cardiometabolic risk factors. Further research into new treatment options is urgently needed.

PROSPERO registration number

CRD42015016148.
A legislative gender-equality norm as a catalyst for change? Discursive convergence in the case of the Swedish Parliament
Authors: Erikson Josefina , Freidenvall Lenita
Published: October 2020

This article addresses the establishment of gender-equality norms in a case often presented as one of the most gender-equal legislatures in the world, namely, the Swedish Parliament (Riksdagen). Based on a series of in-depth interviews between 2005 and 2016 with 90 legislators in the Swedish Parliament, we ask whether there is agreement over gender-equality problems in Parliament that cut across gender and party affiliation, and whether there is convergence over time in this regard. Our findings show that there is a trend of convergence of the gender-inequality framings over time, which indicates the establishment of a shared legislative gender-equality norm. We suggest that a legislative gender-equality norm might work as a catalyst for progressive and continuous work in this area.
Integrated photonic neural network based on silicon metalines
Authors: Zarei Sanaz , Marzban Mahmood-reza , Khavasi Amin
Published: October 2020

An integrated photonic neural network is proposed based on on-chip cascaded one-dimensional (1D) metasurfaces. High-contrast transmitarray metasurfaces, termed as metalines in this paper, are defined sequentially in the silicon-on-insulator substrate with a distance much larger than the operation wavelength. Matrix-vector multiplications can be accomplished in parallel and with low energy consumption due to intrinsic parallelism and low-loss of silicon metalines. The proposed on-chip whole-passive fully-optical meta-neural-network is very compact and works at the speed of light, with very low energy consumption. Various complex functions that are performed by digital neural networks can be implemented by our proposal at the wavelength of 1.55 µm. As an example, the performance of our optical neural network is benchmarked on the prototypical machine learning task of classification of handwritten digits images from the Modified National Institute of Standards and Technology (MNIST) dataset, and an accuracy comparable to the state of the art is achieved.
Switchable broadband terahertz spatial modulators based on patterned graphene and vanadium dioxide
Authors: Ye Longfang , Chen Xueer , Zhu Chunhui , Li Weiwen , Zhang Yong
Published: October 2020

We numerically demonstrate a switchable broadband terahertz spatial modulator composed of ginkgo-leaf-patterned graphene and transition material vanadium dioxide (VO2). The phase transition property of VO2 is used to switch the spatial modulator from absorption mode to transmission mode, and the graphene behaves as dynamically adjustable material for a large scale of absorption and transmittance modulation. When VO2 is in the metallic state and the Fermi energy of graphene is set as 0.8 eV, the proposed modulator behaves as a broadband absorber with the absorbance over 85% from 1.33 to 2.83 THz. By adjusting the graphene Fermi level from 0 to 0.8 eV, the peak absorbance can be continuously tuned from 24.3% to near 100% under the absorption mode, and the transmittance at 2.5 THz can be continuously tuned from 87% to 35.5% under the transmission mode. To further increase the bandwidth, a three-layer-patterned-graphene is introduced into a new modulator design, which achieves a wide bandwidth of 3.13 THz for the absorbance over 85%. By the combination of the tunability of graphene and VO2, the proposed modulators not only can flexibly switch between dual-functional modulation modes of absorption and transmission but also possess deep modulation depth. Benefitting from the excellent modulation performance, the proposed switchable dual-functional spatial modulators may offer significant potential applications in various terahertz smart optoelectronic devices.
Compensated-beacon adaptive optics using least-squares phase reconstruction
Authors: Banet Matthias T. , Spencer Mark F.
Published: October 2020

In this paper, we quantify the benefits of compensated-beacon adaptive optics (CBAO) relative to uncompensated-beacon adaptive optics (UBAO) using wave-optics simulations. Throughout, we present results for both the Shack-Hartmann wavefront sensor (SH-WFS) and the digital-holographic wavefront sensor (DH-WFS). Given weak to moderately strong scintillation conditions, the results show that the two noiseless sensors offer similar performance in terms of the peak Strehl ratio when using similar subaperture sampling and least-squares phase reconstruction. Specifically, CBAO leads to an average performance boost of 17% for the SH-WFS and 26% for the DH-WFS relative to UBAO for the turbulence scenarios studied here.
Giant low-field tunability of THz transmission in patterned magnetic split-ring metastructures
Authors: Zhang Xiaoyu , Chen Yajie , Zhao Lei , Tan Yang , Zhang Qiang , Ma Chunlan , Harris Vincent G.
Published: October 2020

Mirror-asymmetric split-ring metamaterials with high quality factor in the terahertz (THz) band, consisting of patterned high magnetic permeability and low coercivity FeNHf films deposited on high resistivity silicon substrates, were studied for their magnetic field tunable response in frequency and transmission. Dynamic tuning of terahertz transmission and electromagnetic resonance modes were investigated theoretically and experimentally as a function of magnetization of the FeNHf film. Experimental results indicate that the metamaterial structure provides a giant tunability of resonance frequency (Δfr/fr=3.3%) and transmittivity (21%) at a frequency of 0.665 THz under a low magnetic field of H=100 Oe. Remarkable tuning coefficients of frequency and transmittivity, 0.23 GHz/Oe and 0.21%/Oe, respectively, were measured. Finite difference time domain simulations reveal that the incredible tunability stems predominately from the response of the THz dynamic magnetic field to magnetization. As a result, the metamaterial, consisting of a simple magnetic split-ring microstructure, provides previously unimagined paths to tunable devices for potential use in emerging THz technologies including 6G communication systems and networks.
El estudio netnográfico de comunidades transmedia en torno al podcast: nuevos horizontes en la investigación de ecologías de aprendizaje digitales
Authors: Celaya Iñaki , Naval Concepción , Arbués Elena
Published: October 2020

El mundo digital está asistiendo a una explosión de ecologías de aprendizaje conformadas en torno a los cibermedios. Casos como el del podcasting, un medio emergente cuyos contenidos aglutinan comunidades virtuales que interactúan de forma horizontal, intercambiando y co-construyendo conocimiento. En consecuencia, este trabajo aborda las comunidades de aprendizaje relativas al podcast mediante un proceso reflexivo centrado en reducir la confusión que genera la naturaleza virtual del objeto de estudio: unos espacios de participación fragmentados y coordenadas espaciotemporales distintas a las del mundo real. Para ello, se utiliza la netnografía para conceptualizar la comunidad de aprendizaje virtual y analizar su estructura transmedia, repartida en múltiples escenarios de participación social. La propuesta es extrapolable a otras comunidades virtuales y busca atraer a la comunidad educativa hacia entornos digitales que se sitúan en el ámbito de la educación no formal.
RESISTANCE OF COMPRESSION ELEMENTS STRENGTHENED WITH HOOPS MADE OF SELF-COMPACTING FIBER CONCRETE TO STRESSES ARISING FROM BENDING AND AXIAL LOADING
Authors:   Togliatti State University, Togliatti, Russian Federation, Podnebesov P , Teryanik V
Published: October 2020

The results of the experimental study of the influence of the type of concrete in the hoop on the strength and deformability of compressed reinforced elements, tested on axial compression, are given. It is shown that the capacity of reinforced elements increases due to the hoop effect. A method of calculating reinforced elements subject to triaxial stress in round cross-section hoops is given
ABOUT REDUCING ENERGY CONSUMPTION DURING THE SANDS CONCENTRATION PROCESS
Authors:   Togliatti State University, Togliatti, Russian Federation, Salnikov S , Karandaev G ,   EcoTrans, LLC, Togliatti, Russian Federation,   3 Hydromechstroyproject, LLC, Togliatti, Russian Federation
Published: October 2020

The article analyzes the results of the production study of the effect of sand-size segregation in the conical screen underflow pipeline. These results lead to the identifying of the main requirements to the construction of tapering chute. The work gives the results of the laboratory study of the tapering chute model. The results prove the possibility of sand benefication without using additional energy. The schematic diagram of sands enrichment technology in tapering chutes in the gravity hydrotransport process with the expected quality indicators is offered.
DEVELOPMENT AND STUDY OF SELF-COMPACTING CONCRETE CHARACTERISTICS USING THE MATERIALS OF THE CHELYABINSK REGION
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Matveyev D , Ivanov I , Chernykh T , Kramar L
Published: October 2020

Composition of the self-compacting concrete B30-B40 is developed. It is proved that a fine granulated blast-furnice slag has a strong influence on stabilization of rheological properties of selfcompacting concrete. It is necessary to use clean coarse and fine aggregates (sand and gravel) when using polycarboxylates with the aim of getting high workability of concrete mixture
THE MULTIPLE USE OF THE FIRST AND UNDERGROUND FLOORS OF RESIDENTIAL BUILDINGS
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Gorbatenko A , Ignatiev U
Published: October 2020

Modern intensive traffic and pedestrian flows at city roads significantly affects (by noise and air pollution)the residential facilities’ first and second floors. The same applies to the driveways and sidewalks of micro-districts and quarters. All this leads to the decrease of living quality, hence the quality of the residential area’s location on the first and second floors. Therefore, the trend to place public service institutions on the first and second floors of residential buildings is completely justified.
DEVELOPMENT OF THE CONSTRUCTION MANAGEMENT SOLUTIONS USING BUILDING INFORMATION MODELING (BIM)
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Vaisman S , Baiburin A
Published: October 2020

The paper deals with methods for development of process control and management documentation in construction with the help of Building Information Modeling (BIM). Information modeling is applied to design projects on the erection process for vertical cylindrical tanks with external platforms. The new approach allows increasing managerial and engineering reliability of construction and installation works.
THE COMPETENCE OF BACHELORS MAJORING IN 08.03.01 CONSTRUCTION TO PERFORM CONSTRUCTION AND TECHNICAL EXPERTISE IN CASE OF SOLVING CIVIL DISPUTES
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Averin S
Published: October 2020

Russian courts often consider disputes in the sphere of construction, which requires the support of a forensic expert. That’s why the issue of experts’ competence is quite topical. The study on required competence is carried out on the basis of data received during the practical activity of forensic experts. In the course of study typical mistakes which are made by forensic specialists are identified. The author suggests the solution of specified problems and the algorithm of conducting forensic examination. All existing methods are oriented to economists who get supplementary education in the field of construction and work as construction experts. The obtained in the course of the investigation results are aimed at bachelors majoring in 08.03.01 Construction, which is a truly new approach to consideration of this issue. It will favour the improvement of quality of construction examination
THE IMPROVEMENT OF BITUMEN APPLICATION PROPERTY BY INTRODUCING MODIFYING ADDITIVES OF NATURAL ORIGIN
Authors:   Kurgan State Agricultural Academy by T.S. Maltsev, Kurgan, Russian Federation, Grehov P , Zavodov S
Published: October 2020

The possibility of the introduction of the flask in asphalt concrete as a mineral supplement. The results of studies of the flask’s effect on the bitumen adhesion to the mineral material in the asphalt mixture. The results allow to receive the asphalt mix with a higher index of bitumen adhesion to the mineral material. Shows the production of asphalt concrete technology with the introduction of the flask as a mineral supplement.
THE EFFECT OF ADDITIVES ON HEAT EMISSION OF CONCRETE
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Butakova M , Galyauv R , Saratkov A
Published: October 2020

The paper is focused on the effect of chemical additives, namely plasticizing agents on the heat emission in the context of cement hydration. The authors find to what extent each additive affects this process for CEM II 32.5H and CEM I 42.5H. They come to the conclusion that this additive decreases the maximum temperature of the mixture heating. In laboratory conditions the standard consistency for all compositions is chosen in accordance with GOST 310.3-76. The research results are obtained with the help of an adiabatic calorimeter. The area to determine the amount of heat generated over a defined period is calculated.
THE STRUCTURE OF SYSTEM FOR PROVIDING MICROCLIMATE OF THE WORKPLACE OF ASSEMBLERS OF RADIO EQUIPMENT
Authors:   Kalashnikov Izhevsk State Technical University, Izhevsk, Russian Federation, Nekrotyuk A , Korepanov E
Published: October 2020

Described the structure of the assurance system of microclimate parameters of the workplace in the workshop. Assembly of electronic equipment. Developed functional and structural model of the air conditioning system of the shop. Described mathematical model of the regulation of microclimate parameters, energy-efficient system. According to the preliminary calculation of the velocity distribution of air flow in the working area of the calculated indicator of the comfort thermal sensation PMV. It is shown that the well-being of the installers is crucial when choosing constructive solutions local ventilation. Formulated the problem and challenges for future research on the creation of an effective system of provision of the microclimate, characterized by a large number of alternative solutions and a variety of diverse factors
THE RECONSTRUCTION OF ON-SHORE PUMPING STATION COMBINED WITH A WATER INLET WITHOUT A STOP OF WORK OF CHELYABINSK METALLURGICAL PLANT
Authors:   South Ural State University, Chelyabinsk, Russian Federation, Arkanova I , Noskov A ,   Chelyabinsk Metallurgical Plant, Chelyabinsk, Russian Federation
Published: October 2020

The plan of reconstruction of an on-shore pumping station combined with a water inlet of Chelyabinsk Metallurgical Plant (CMP) is developed. The authors give characteristics of the quality and amount of water, needed for the main production of CMP. The inspection of the on-shore pumping station combined with the water inlet of CMP is carried out. The need for reconstruction for reliability control and compliance with modern requirements of water intake of an industrial enterprise, which in turn is connected with the expansion of production at CMP is proven. The basic equipment is specified. It leads to the enlargement of the pumping station itself.
Modification of ACI209R-92 Concrete Shrinkage Model for Partial Replacement of Cement with Fly Ash and Sand with Pond Ash
Authors: Rath Badrinarayan , Deo Shirish , Ramtekkar Gangadhar
Published: October 2020

A lot of researchers have been committed to studying various mathematical models for forecasting shrinkage strain developed in concrete and have found many computational models. Those models only predict the linear shrinkage of concrete. But volumetric shrinkage gives clear ideas about shrinkage strain produced inside the structure. However, the previous investigation usually focused on the shrinkage of control cement concrete or cement was replaced with one kind of supplementary cementitious material. The influence of multiple supplementary materials as both cement and sand replacement on shrinkage has not been studied, and this is very important in practice for saving cement and sand. In this research, cement has been replaced with fly ash up to 40 % and sand has been replaced with pond ash up to 20 % individually as well as simultaneously. A total of 27 mixes has been prepared by using three water–cement ratios, and the influence of fly ash and pond ash on volumetric shrinkage has been studied. It is found that when cement is replaced with fly ash up to 40 %, the shrinkage of concrete shows 47 % less than the shrinkage result of control concrete. Similarly, the replacement of sand with pond ash up to 20 % results in the reduction of shrinkage of concrete up to 22 %, and the results for the simultaneous replacement of cement with fly ash and sand with pond ash show a reduction of shrinkage of concrete up to 62 % as compared with the shrinkage of control concrete. Shrinkage strains for all 27 mixes have been determined by using different shrinkage models as well as a laboratory test. It is found that the shrinkage strain found from the ACI model matches with shrinkage strain determined from laboratory tests in a better way as compared with other models. Further, the ACI model has been modified to determine the shrinkage strain of concrete, prepared from supplementary cementitious materials.
Comparison of Two Laboratory Methods for Measuring Soil Critical Temperature
Authors: Oh Hyunjun , Tinjum James M.
Published: October 2020

Coupled heat and moisture transfer above a critical temperature is important in various geothermal applications (e.g., geothermal heat exchangers, buried power cables, and energy piles) because of its impact on nonsteady soil thermal properties. In this study, temperature and moisture content of seven sandy soils were measured using two laboratory approaches—vertical and radial—to evaluate the critical temperatures. The vertical approach measured temperature and moisture data from top to bottom of a soil column, and the radial method obtained the measurements from center to outside of the specimen. To validate the test results, computational modeling was also carried out in MATLAB. Although the results obtained from radial testing included rapid changes in temperature gradients near the boundaries between dry and wet zones, ambiguous temperature profiles (i.e., gradual gradients over the entire range) were observed in vertical testing possibly because of horizontal boundary heat losses. In contrast to the gradual temperature gradients, moisture content profiles showed significant variations near the transitional regime, thus the critical temperatures were determined based on both temperature and moisture profiles. Average critical temperature for seven soils was 45.8°C, and the critical temperature was dependent on the void ratio. As void ratio decreased, critical temperature increased with a corresponding decrease in the size of the dry zone. The critical temperatures obtained from radial testing were higher (up to 5.2°C higher) and took more time to reach steady-state condition (up to 9 h longer) than those obtained from vertical testing. Because there are limited data and methodology in published studies that discuss a standard methodology to measure soil critical temperature, a consistent, universally accepted, procedural-based method is needed for the measurement or determination of the critical temperature.
An Investigation and Optimization Study of Borax Content in the Slime Products
Authors: Mak S. L. , Chiu W. H. , Tang W. F. , Li C. H.
Published: October 2020

The slime toys were invented by Mattel in 1976. Slime is a reversible cross-linking gel made from guar gum. The slime toys were further developed into many different products and became one of the most popular toys. Despite buying slime products with attractive packaging, some children love to make their own slime products. The Consumer Council of Hong Kong published a report in 2019 to alert the public about the safety problems because of the excess boron content in those slime products in 2019. Some reported cases of slime product players having adverse health symptoms, which made the government concerned about the safety of slime products. The objectives of the study were to investigate the concentration of boron compounds in the four selected slime toys from the market and suggest a safety ingredient formula to the users to make their own do-it-yourself slime toys. Because only the European Union has relevant safety regulations and standards to limit the concentration of boron compounds in the toys, amendment of the current children’s products safety regulations and standards is required. By fulfilling the objectives, the consumers can make sure that their children who play with slime products can do so without the potential adverse health effects.
Detecting Selection from Linked Sites Using an F-Model
Authors: Galimberti Marco , Leuenberger Christoph , Wolf Beat , Szilágyi Sándor Miklós , Foll Matthieu , Wegmann Daniel
Published: October 2020

Allele frequencies vary across populations and loci, even in the presence of migration. While most differences may be due to genetic drift, divergent selection will further increase differentiation at some loci. Identifying those is key in studying local adaptation, but remains statistically challenging. A particularly elegant way to describe allele frequency differences among populations connected by migration is the F-model, which measures differences in allele frequencies by population specific FST coefficients. This model readily accounts for multiple evolutionary forces by partitioning FST coefficients into locus- and population-specific components reflecting selection and drift, respectively. Here we present an extension of this model to linked loci by means of a hidden Markov model (HMM), which characterizes the effect of selection on linked markers through correlations in the locus specific component along the genome. Using extensive simulations, we show that the statistical power of our method is up to twofold higher than that of previous implementations that assume sites to be independent. We finally evidence selection in the human genome by applying our method to data from the Human Genome Diversity Project (HGDP).
ОРГАНІЗАЦІЙНО-ПЕДАГОГІЧНІ УМОВИ ЗАБЕЗПЕЧЕННЯ ЯКОСТІ
ФІЗИЧНОГО ВИХОВАННЯ ШКОЛЯРІВ
Authors: Москаленко Наталія , Яковенко Артем , Овчаренко Сергій , Сидорчук Тетяна
Published: October 2020

Мета: визначити організаційно-педагогічні умови забезпечення якості фізичного виховання учнів закладів загальної середньої освіти України на основі екстраполяції зарубіжного досвіду.

Матеріал і методи: дослідження проводились у Придніпровській державній академії фізичної культури і спорту. У ході дослідження використано такі методи: теоретичний аналіз та узагальнення даних науково-методичної літератури та документальних матеріалів, метод порівняння, метод системного аналізу.

Результати: визначено організаційно-педагогічні умови забезпечення якості фізичного виховання школярів, дотримання яких дозволить досягти належного рівня фізичної підготовленості та здоров’я учнів, сформованої системи знань учнів в сфері фізичного виховання, у тому числі, для організації самостійної рухової активності, сформованої звички до занять фізичними вправами протягом всього життя, стійкого інтересу учнів до видів рухової активності, наявності соціальних зв’язків та навичок взаємодії, розвиненої здатності учителя та учнів здійснювати рефлексію.

Висновки: аналіз та узагальнення досвіду організації фізичного виховання в країнах Європи, Азії та США дозволили визначити організаційні та педагогічні умови забезпечення якості процесу фізичного виховання, які можна застосовувати в системі загальної середньої освіти України.

Ключові слова умови, якість, зарубіжні країни, досвід, критерії ефективності.
ОСОБЛИВОСТІ ВИКОНАННЯ РЕЗУЛЬТАТИВНИХ УДАРІВ У ВОРОТА ФУТБОЛІСТАМИ В ІГРАХ КОМАНД ВИСОКОГО РІВНЯ
Authors: Перцухов Андрій , Шаленко Віктор
Published: October 2020

Мета: встановити особливості виконання результативних ударів у ворота футболістами високої кваліфікації.

Матеріал і методи: реєстрація техніко-тактичних дій (ТТД) здійснювалася на прикладі ігор команд-учасниць Ліги чемпіонів УЄФА сезону 2019/2020. Усього було проаналізовано 108 ігор. У роботі застосовувалися такі методи дослідження: аналіз науково-методичної літератури, реєстрація ТТД, методи математичної статистики.

Результати: у роботі представлено дані, які характеризують особливості виконання результативних ударів у ворота футболістами в іграх команд високого рівня. Усього було зареєстровано й проаналізовано 344 голи в 108 іграх команд-учасниць Ліги чемпіонів УЄФА сезону 2019/2020. Усі результативні удари класифікувалися за часом, місцем, ситуацією, способом та умовами виконання.

Висновки: встановлено, що футболісти високої кваліфікації результативні удари в ворота частіше виконували з 76 по 90 хвилини гри, із зони штрафної площі (крім площі воріт), після передачі м'яча від партнера по команді, першим дотиком, по м'ячу з ґрунту, в нижню частину воріт.

Ключові слова удари, штрафна площа, площа воріт, каркас воріт, провідна нога, стандартне положення, область воріт, ігрове амплуа.
ВИБІР ІГРОВОГО АМПЛУА ПІВЗАХИСНИКІВ І РУХОМИХ НАПАДНИКІВ У ГРАВЦІВ В ЖІНОЧОМУ ВОДНОМУ ПОЛО
Authors: Пилипко Ольга , Пилипко Аліна
Published: October 2020

Мета: розробити та експериментально обґрунтувати методику вибору ігрового амплуа півзахисників і рухомих нападників у гравців в жіночому водному поло.

Матеріал і методи: аналіз та узагальнення літературних джерел, педагогічне спостереження, антропометричні та фізіологічні вимірювання, тестування показників спеціальної плавальної і технічної підготовленості, аналіз ігрової діяльності ватерполісток за допомогою спеціальних протоколів контрольних ігор, методи математичної статистики. Контингент обстежуваних склали члени жіночої збірної команди Харківської області з водного поло, які мали рівень спортивної кваліфікації «Майстер спорту України».

Результати: авторами визначені особливості структури спеціальної підготовленості кваліфікованих ватерполісток, які виконують функції півзахисників і рухомих нападників, досліджений взаємозв’язок між показниками фізичного розвитку, технічної і спеціальної плавальної підготовленості та ефективністю ігрових дій спортсменок даного амплуа, розроблено модельні характеристики найбільш значущих показників структури спеціальної підготовленості кваліфікованих ватерполісток, які можуть служити орієнтирами для визначення ігрового амплуа півзахисників і рухомих нападників.

Висновки: визначення ігрового амплуа у гравців в жіночому водному поло повинно проводитися на підставі комплексного аналізу параметрів, які відображають різні сторони структури спеціальної підготовленості кваліфікованих спортсменок.

Ключові слова водне поло, спортсменки, півзахисники, рухомі нападники, показники, взаємозв'язок, модельні характеристики.
Square Roots of Kepler Ellipses, Electrons and Rydberg Atoms in a Magnetic Field
Authors: Stepanovsky Yu. P.
Published: October 2020

Young Kepler’s daring ideas on the structure of the Solar system are applied to the analysis of planetary distances in the exoplanetary system HD 10180. Using Zhukovsky’s transformation, the essence of the spinor regularization of Kepler’s problem is explained as extracting the square root of an ellipse and using a Kepler eccentric anomaly instead of the usual time. The achievements of Kharkiv radio astronomers in the search for radio recombination lines of Rydberg carbon atoms at the UTR-2 radio telescope are considered. A generalized spinor regularization of the Kepler problem is used to analyze the energy spectra of Rydberg hydrogen atoms in a magnetic field.
Interpretation of the Spin Torque Sign Change in F/N/F Structures in Terms of a Mechanical Analogy
Authors: Bazaliy Ya. B.
Published: October 2020

A useful interpretation of the spin-accumulation and spin-current distributions in magnetic nanostructures with diffusive transfer has been discussed. A mathematically equivalent mechanical system was proposed that provides an intuitive understanding of the dependence of the spin-transfer torque values on various parameters. In particular, it gives a clear explanation for the sign change of the spin-transfer torque in asymmetric F/N/F structures.
Spin-Polarized Current-Driven Ferromagnetic Domain Wall Motion with a Skyrmion-Like Building Block
Authors: Gorobets O. , Gorobets Yu. , Tiukavkina I. , Gerasimenko R.
Published: October 2020

The purpose of the research is the construction of an analytic model for the description of a spin-polarized current-driven ferromagnetic domain wall motion with a skyrmion-like building block. The motion velocity of the ferromagnetic domain wall with a skyrmion-like building block is found as a function of the driving torques and an external magnetic field strength.