bluuebunny/crossref_metadata_2025 huggingface dataset:
Screening for tuberculosis among sanitation workers in a tertiary care hospital, Delhi, India: a cross-sectional study
Authors: A. Mogan K. , Kapoor Richa , Lukhmana Shveta , Bharti Aakanksha , Goyal Mohit
Published: November 2020

Background: The surveillance of TB reduces disease transmission by shortening the duration of infectiousness and this reduces the incidence of TB infection and consequently contributes to reduced incidence of TB disease. The study aimed to screen for tuberculosis among the sanitation workers in a tertiary care hospital and assess the associated factors to provide the burden of tuberculosis among sanitation workers.Methods: The present study was conducted in Safdarjung Hospital, one of the largest Tertiary care hospital in India, located in the Southern part of Delhi. This was a cross-sectional study conducted among the sanitation workers currently employed in the hospital. 362 workers were included in the study using a convenient sampling (non-probability) method. The participants were interviewed with a pretested, semi-structured, semi-open ended questionnaire, which was based on the guidelines of screening of TB of Revised National Tuberculosis Control Program (RNTCP). The data was entered in Google forms and analyzed for completeness and cleaned for errors and missing values. Data analysis was done using licensed SPSS software version 21.0.Results: Out of total 362 workers who were screened for TB, 28 (7.7%) gave a positive history for presumptive TB. The symptoms reported among them were cough more than 2 weeks (85.7%), fever or night sweats more than 2 weeks (46.4%), significant weight loss (53.5%), hemoptysis (14.2%), and symptoms regarding EPTB (53.5%).Conclusions: It is important to protect the health care workers working in hospital setting as they are under higher risk and screening should be conducted at regular intervals.
Improved Vector Control of a Counter-Rotating Wind Turbine System Using Adaptive Backstepping Sliding Mode
Authors: Yahdou Adil , Djilali Abdelkadir Belhadj , Boudjema Zinelaabidine , Mehedi Fayçal
Published: November 2020

The vector control (VC) method based on proportional-integral (PI) controllers of a doubly fed induction generator (DFIG) integrated in a counter rotating wind turbine (CRWT) system have many problems, such as low dynamic performances, coupling effect between the d-q axes and weak robustness against variation parametric. In order to resolve these problems, this research work proposes an adaptive backstepping sliding mode (ABSM) controller. The proposed control strategy consists in using dynamic-gains that ensures a better result than a conventional VC method. Stability of the proposed ABSM control approach has been proved by the Lyapunov method. Simulation results depicted in this research paper have confirmed the good usefulness and effectiveness of the proposed ABSM control.
Analysis of the subject of lifelong education : feature and organic connection
Authors: Zhou Wei
Published: November 2020

Summary : The subject of lifelong education is the provision of school premises for lifelong education , Teaching Activities , Administrative Services , Policies and Systems , a variety of organizational machines such as theoretical research construct, Show distinct diversity, Open Features; in lifelong education, School ,Government , Community , Enterprise and library , Museums and other principals The has A new change in its meaning, features and so on ; in the people-centered concept , lifelong education principals need to break through the system , Resource Open , Organization Innovation and tool selection to achieve mutual communication and organic connections , To build an open , flexible,, Effective lifelong education system .
Research and Application of Vocational Ability Training——Take
Computer Application Technology as an Example
Authors: Wang Ying
Published: November 2020

To better improve the professional ability of students is the focus of talent training in higher vocational colleges in China in the new era. The Computer major is a relatively popular major in China’s higher vocational colleges. With the continuous development of higher vocational education, the issue of professional ability training for computer majors has attracted widespread attention. This article starts with the analysis of the problems existing in the training of computer professional vocational ability, and focuses on the research and application of computer professional vocational ability training. It is hoped to use the professional ability as the starting point to further optimize the vocational ability training model of computer science in higher vocational colleges in China and provide more application-oriented computer talents to the society.
The Construction and Application of the In-class Flipped Teaching
Model Based on Micro-classes in Junior High School Information
Technology Courses
Authors: Qing Xinfei , Tian Min , Zhou Jie
Published: November 2020

the in-class flipped teaching model concentrates the teaching links of flipped class in the classroom, and completes the process of knowledge construction to internalization in class. This restructuring of teaching structure is more in line with the current education situation in China, but compared with the flipped classroom, China has less theoretical research and practical exploration of the flipped teaching model in class. Therefore, through the research on the current situation of flipped classroom teaching models at home and abroad, combined with the characteristics of junior high school information technology courses, a micro-class-based in-class flipped teaching model was constructed and implemented in junior high school information technology courses. The survey results were obtained to assist related theories and practical exploration.
Construction and Research of College Students’ Educational
Management Ecosystem in the Micro Era
Authors: Wang Baofeng
Published: November 2020

With the acceleration of educational development and technological development, society continues to advance, technology continues to innovate, and related concepts are also updated. The network is playing an increasingly important role in people’s social production and life. With the help of the Internet and related information technology applications, education is provided with a broader resource and interactive platform, and related technology and concept updates have also brought new opportunities and challenges to the development of education. With the advent of the micro era, the Microsoft platform has brought great convenience to people’s life, study and work. In the micro era, some new problems have emerged in education management. In this regard, it is necessary to clarify the impact of college student education management in the micro era, and actively explore specific countermeasures for the construction of the college student education management ecosystem in the micro era.
Research on the Role of Mobile Learning Technology in Promoting
Deep Learning of College Students
Authors: Liu Xiangsen , Ye Zhenzhen , Jiang Dongmei
Published: November 2020

As the primary productive force, education plays a huge role in the development of modern society. Traditional educational activities mainly focus on the teaching of students’ superficial knowledge and skills, which are no longer able to meet the current society’s demand for talents. At present, it is required to promote the development of in-depth thinking of college students, stimulate their innovation and creativity, and enable students to better contribute to social production. Therefore, it is very important to introduce the concept of deep learning for college students and establish a student-based teaching model. The author mainly uses mobile learning technology to analyze the functional role of mobile learning technology in promoting deep learning activities for college students, and proposes ways to effectively grasp mobile learning technology in future university informatization education activities.
Development and Application of an Interactive Teaching Model for
the ‘Introduction to Environmental Protection’ Course Teaching
based on the Student’ s Personal Individual Needs
Authors: Li Junfeng , Ren Yucheng , Reaihan E , Wang Meng
Published: November 2020

The interactive teaching model is a modern method that takes the students as a main body and promotes their innovative ability teaching and training. The object of this paper is to discuss the application of interactive teaching model for the course teaching of the ‘Introduction to Environmental Protection’ course for the students major in the architecture based on the student`s personal individual needs. The main reforms include five aspects: the diverse forms of the class, the feedback mechanism for homework, the encouragement of the students’ answering questions, the customized homework and the reform of the assessment mode. Through the feedback of the classroom and the questionnaire, it can be seen that after the classroom teaching reform, the classroom interaction was increased, the students’ participation and the classroom enthusiasm was improved, the knowledge points’ mastering became better and the students’ satisfaction was improved obviously. The mode of teaching reform has laid a solid foundation for the popularization and application of the introduction courses of other majors.
Analysis of Information Security Maintenance Countermeasures in
Power Automation Communication Technology
Authors: Luo Kun
Published: November 2020

This article is divided into three parts. The first part is to summarize the current situation of the use of power automation communication systems, information security, and the basic requirements of the current society for the information security of the system. The second part analyzes the current information security problems of power communication technology from human factors, natural factors, and technical loopholes. The third part explores the maintenance countermeasures to improve the information security of power automation communication technology and systems.
Analysis of Ways to Strengthen the Management of Marine Fishery
Resources in China in the New Period
Authors: Chen Zhi , Liu Yan , Yang Chaojie , Xing Xiaoxuan , Wang Qianqian , Su Lican
Published: November 2020

This article mainly starts with the concept and basic characteristics of China’s marine fishery resources. On this basis, it analyzes the utilization status of China’s marine fishery resources and the problems existing in the management of marine fishery resources for discussion, and finally proposes effective ways to strengthen the management of marine fishery resources, aiming at providing help for the sustainable development of China’s marine fishery resources.
Illuminate the Hidden Pain in Our Hearts——Analysis of the Image of “Aunt” in Mo Yan’s Novel Frog
Authors: Yuan Hui
Published: November 2020

Frog is a long-form masterpiece created by Mo Yan with the great concentration that touches the most painful part of the Chinese soul. The novel consists of four long letters and a drama written by the playwright Tadpole to the Japanese writer Sugitani. It is about the life experience of an “aunt”, a Chinese rural obstetrician and gynecologist, with vivid and touching details showing the sixty years of undulating birth history in rural China.
The application of classroom interactive teaching mode in English teaching
Authors: You Lihua
Published: November 2020

College English teaching has an important impact on students’ future employment, participation in postgraduate entrance exams and other activities, and their ability to use English in the future. Under the current background of quality-oriented education, adopting classroom interactive education mode for college English teaching can effectively activate the classroom atmosphere, help students consolidate English knowledge, promote the development and implementation of English education, and improve the quality of college English teaching.
Research on Teaching Reform of Basic Courses of Landscape
Architecture Design in Applied Universities
Authors: Zhou Yan , Fan Lei
Published: November 2020

Design foundation is an introductory course for landscape architecture majors, and it occupies a very important position in the entire landscape architecture professional teaching. This article is mainly based on the relevant requirements of application-oriented talent training, combined with the current teaching status of landscape architecture design professional courses, analyzes the problems in actual teaching, and makes some adjustments in the teaching content to reform the basic courses of landscape architecture design. The teaching method enhances the enthusiasm of students to learn, and lays a solid foundation for cultivating outstanding applied design talents.
The Exploration of the Organic Combination of Innovation and
Entrepreneurship Education and Professional Education
Authors: Long Zhuoqun
Published: November 2020

Under the influence of China's education reform, the combination of innovation and entrepreneurship education and professional education has become a new training model for more colleges and universities to cultivate talents, in order to respond to the increasingly severe employment situation in the society, and to train talents in all aspects. For all colleges and universities, cultivating students' independent entrepreneurship ability and doing a good job in innovation and entrepreneurship training and education can provide more development directions for college students and make them take independent entrepreneurship as a goal of subsequent development. This article first analyzes the current situation of the combination of professional education and innovation and entrepreneurship education, and then explores the method of organic combinationthe of professional education and innovation and entrepreneurship education.
The levels of sICAM-1, sELAM-1, TNFα and sTNFR1 proteins in patients with colorectal adenocarcinoma in tumor and corresponding normal mucosa
Authors: Strzelczyk Joanna K. , Cuber Piotr , Bochon Benjamin , Gajdzik Krzysztof , Strzelczyk Janusz , Krakowczyk Łukasz , Wiczkowski Andrzej , Owczarek Aleksander Jerzy , Ostrowska Zofia
Published: November 2020

Colorectal cancer is a common malign disease of the gastrointestinal tract. The cancer survival rate depends on the stage of the disease at detection time. It is well known that several molecular mechanisms are involved in cancer and some molecules might affect or modulate neogenesis. The aim of the study was to assess the levels of sICAM-1, sELAM-1, TNFα and sTNFR1 protein in tumor and corresponding normal mucosa in a group of patients with colorectal adenocarcinoma and also associations of these parameters with demographic and clinical profiles of the patients. Tissue specimens were obtained during resection of neoplastic lesions. Protein levels were assayed in tissue homogenates by ELISA. The protein level of sICAM-1 in tumor was significantly increased in comparison to the corresponding normal mucosa (80.06 ng/mg vs 69.53 ng/mg, p=0.02). Furthermore, a significant positive correlation between sICAM-1 and sTNFR1 proteins levels in tumor (rs=0.58, p<0.001) and in corresponding normal mucosa (rs=0.48, p<0.001) was found. Also, significant correlations in corresponding normal mucosa were found between sELAM-1 and sICAM-1 (rs=0.58, p<0.001) and between sTNFR1 and sELAM-1 (rs=0.57, p<0.001). Significantly higher level of sTNFR1 in corresponding normal mucosa samples of patients with distant metastases was observed (p=0.04). Obtained results suggest that sICAM-1 protein could be considered as colorectal cancer marker. Furthermore, sTNFR1 also has the potential to become a good prognostic marker used during monitoring of the patients. Nevertheless, a further study in this area to confirm this correlation is required.
A Journey of Doing Research “In a Good Way”: Partnership, Ceremony, and Reflections Contributing to the Care and Wellbeing of Indigenous Women Living with HIV in Canada
Authors: Peltier Doris , Martin Carrie , Masching Renée , Standup Mike , Cardinal Claudette , Nicholson Valerie , Kazemi Mina , Kaida Angela , Warren Laura , Jaworsky Denise , Gervais Laverne , De Pokomandy Alexandra , Bruce Sharon , Greene Saara , Becker Marissa , Cotnam Jasmine , Larkin Kecia , Beaver Kerrigan , Bourassa Carrie , Loutfy Mona
Published: November 2020

The relationship between the First Peoples of Canada and researchers is changing as processes of self-determination and reconciliation are increasingly implemented. We used storytelling and ceremony to describe a historic event, the Indigenous Women’s Data Transfer Ceremony, where quantitative data of 318 Indigenous women living with HIV were transferred to Indigenous academic and community leaders. Relationship building, working together with a common vision, the Ceremony, and the subsequent activities were summarized as a journey of two boats. The Truth and Reconciliation Commission of Canada's Calls to Action and Indigenous ethical principles were central to the process. The article ends with team members’ reflections and the importance of shifting power to Indigenous Peoples in regard to data collection, their stories, and the resulting policies.
Neurorozwojowy wymiar gestu wskazywania palcem – rozwój i stymulacja
Authors: Siudak Anna , Bielenda-Mazur Ewa
Published: November 2020

Artykuł stanowi kontynuację rozważań autorek nad gestem wskazywania palcem (GWP) u niemowląt. Podstawy teoretyczne zawarte w tekście Gest wskazywania palcem w świetle doniesień neurobiologicznych zostały dopełnione o rozważania nad konsekwencjami braku GWP u dzieci oraz o ćwiczenia stymulujące, które zaprogramowano z uwzględnieniem trzech aspektów istotnych dla jego pojawienia się: stymulacji motorycznej, poznawczej oraz językowej. Przedstawiony autorski model oddziaływań terapeutycznych stanowi podstawę do budowania u dziecka zdolności komunikowania się – początkowo z wykorzystaniem gestu wskazywania, a następnie gestu werbalnego.
Postępowanie logopedyczne w przypadku dzieci z niewielkim nasileniem niepłynności mówienia
Authors: Woźniak Tomasz
Published: November 2020

Artykuł podejmuje zagadnienie postępowania logopedycznego w przypadku dzieci w wieku przedszkolnym i wczesnoszkolnym, u których występuje niewielkie nasilenie niepłynności mówienia. Jest to ważny problem w praktyce logopedycznej, ponieważ niepłynność mówienia występuje w okresie rozwoju mowy u 5% dzieci. Jąkanie dotyczy tylko 1% i tylko w przypadku dzieci jąkających się napotykamy jasno określone procedury terapii. Praca logopedy z dziećmi z mniej nasiloną niepłynnością, odróżnienie niepłynności rozwojowej od patologicznej oraz odpowiednie działania terapeutyczne i profilaktyczne stają się zasadniczą kwestią terapii. W artykule omówiono zagadnienia podłoża niepłynności u dzieci, jej diagnozy oraz dalszych działań terapeutyczno-profilaktycznych.
Estratégias de leitura e suas contribuições para a formação do leitor nos anos iniciais
Authors: Oliveira Quirino Chayene Andressa de , Guerim Fernandes Geuciane Felipe
Published: November 2020

Esta pesquisa teve como objetivo investigar as contribuições das estratégias de leitura para a formação do leitor nos anos iniciais. Justifica-se pela necessidade de repensar as concepções e práticas de leitura vivenciadas ao longo da formação leitora, apresentando possibilidades e estratégias para a formação de um leitor autônomo. Neste sentido, delineou-se a problemática da pesquisa: Quais as contribuições das estratégias de leitura para a formação do leitor nos anos iniciais? O estudo foi realizado mediante pesquisa bibliográfica, de abordagem qualitativa, em diálogo com Leffa (1999) e Silva (1984,1999) que buscaram compreender as diferentes concepções de leitura, e, Luria (2010); Souza et al. (2010); Souza, Girotto e Silva (2012); Girotto e Souza (2011); Souza e Girotto (2013); Solé (1998), entre outros, que destacaram em seus estudos a importância das estratégias de leitura e da leitura literária como caminho para a compreensão leitora nos anos iniciais.
FIRST REPORT OF THE INVASIVE PEST DROSOPHILA SUZUKII(MATSUMURA, 1931)(DIPTERA DROSOPHILIDAE)ON OLEA EUROPAEAL. IN ITALY
Authors: ORZALI LAURA , MOSCONI FABIO , ROVERSI PIO FEDERICO , BERGAMASCHI VALENTINO , RICCIONI LUCA
Published: November 2020

The fruit crop pest Drosophila suzukii(Matsumura, 1931)(Diptera: Drosophilidae) is a highly polypha-gous invasive pestlisted in the EPPO A2 list. This specieshas been reported as host of a variety of cultivatedplantsandwild fruits.Herein,we report the record of someD.suzukiiviable specimensthatwere found in olives directly collected from the tree branches in four differentsites of Latium and Umbria (Italy). Adults emerging from these pupae were collected and morphological and molecular analysiswere carried out to confirm the speciesidentity. Olive tissues alterations wereobserved in associationwiththe presence of the species.The analysis of the available literature showed us that this is the first record of D. suzukiias a phytophagous species on the olive tree in Italy and probably worldwide
Trabajo a distancia y teletrabajo: una perspectiva de género Ana de la Puebla Pinilla
Authors: Puebla Pinilla Ana de la
Published: November 2020

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Derechos sociales y políticas publicas
Authors: Solozábal Echavarría Juan José
Published: November 2020

Este artículo reseña: Samuel Moyn. Not enough, human rights in an unequal world, Harvard University Press, London 2018.
WHY HEALTH WORKFORCE MATTERS: REFLECTIONS FROM CURRENT PANDEMIC AND PAST PROGRAMS EXPERIENCES
Authors: Atika Nur
Published: November 2020

A well-functioning health system depends largely on the quantity and capacity of health human resources who have responsibilities for organizing and implementing health services. A proper arrangement of health workers in terms of numbers, competencies, and diversity is necessary for responding to healthcare needs and achieving health program goals. The need for adequate and skilled health professionals has become even more urgent in the time of current pandemic situation to ensure the resiliency of health systems. In responding to the COVID-19 pandemic, especially in Indonesia, attention is intensively paid to the aspect of facilities such as hospitals, as well as testing and protective equipment. However, we should not forget that the readiness of human resources including clinicians, nurses, laboratory staff, ambulance drivers, and so on are also of paramount importance.
THE EFFECT OF BURNOUT SYNDROME ON TURNOVER INTENTION USING ORGANIZATIONAL COMMITMENT AS AN INTERMEDIATE VARIABLE
Authors: Santi Maya Weka , Nandini Nurhasmadiar , Alfiansyah Gamasiano
Published: November 2020

Background: The average of employee turnover rate in Surabaya Surgical Hospital was quite high roughly about 16.21% in 2011 until 2015. Employees’ negative behavior or feelings due to long exposure to an emotional stressor are called burnout syndrome which could trigger turnover in an organization.Aims: This study analyzed the effect of burnout syndrome towards turnover intention using organizational commitment as an intermediate variable.Methods: This study was cross-sectional research by involving 126 respondents as samples according to the proportion of each unit at Surabaya Surgical Hospital. Data were analysed statistically using multiple linier regression.Results: Respondents were mostly female (65.1%) and in the age group of 26-35 years (62.7%). Most of them were early adults, permanent employees (95.2%), and undergraduates (89.7%). While the minority have worked for 3 up to 4 years (40.5%). Burnout syndrome had a significant effect on employees’ organizational commitment. Organizational commitment showed a significant effect on turnover intention, while burnout syndrome did not show a significant effect on turnover intention.Conclusion: Burnout syndrome did not directly affect turnover intention but became a possible cause of turnover intention through organizational commitment as the intermediate variable. The results of this study could be the basis for hospital managers to decrease employee’s turnover intention by minimizing burnout syndrome and increasing organizational commitment with a better reward system. Keywords: burnout syndrome, organizational commitment, turnover intention, hospital.
THE EFFECT OF ORGANIZATION’S STRUCTURE AND TASK CHARACTERISTICS ON TEAM EFFECTIVENESS IN TUBERCULOSIS PREVENTION PROGRAM
Authors: Lestyoningrum Sinta Dewi , Rochmah Thinni Nurul , Suminar Dewi Retno , Safira Ulfia Hazna
Published: November 2020

Background: A team is a vital element for an organization. An organization should put efforts to improve team performance even though they might face some obstacles. Organization’s structure and task characteristics resulted in different team effectiveness of primary healthcare centres in preventing tuberculosis (TB) cases in Surabaya.Aims: This study aimed to identify the effect of organization’s structure and task characteristics on team effectiveness of primary healthcare centers in TB prevention program in Surabaya.Methods: The reasearch was a quantitative study using a cross-sectional approach. Questionnaires were disseminated to 43 respondents as the samples selected with a proportional stratified random sampling technique based on the success rate. The respondents consisted of doctors, nurses, and health analysts who were directly involved in the Tuberculosis prevention program. This study used a linear multivariable regression test to confirm the most significant model for the independent variable.Results: The span of control and centralization had a significant effect on task characteristics (sig 0.00; sig 0.017). The dimensions of task characteristics that had a significant effect on team effectiveness were task variety, task identity, and task significance.Conclusion: There was a significant effect of span of control and centralization on task characteristics. The primary healthcare centers should provide access to technology to upgrade the span of control and centralization and their understanding of task characteristics. Keywords: health services, organization’s structure, task characteristics, team effectiveness, tuberculosis.
Cornelia de Lange Syndrome and Psychiatric’s Assistance
Authors: Apriliani Katharina Merry , Setiawati Yunias
Published: November 2020

Cornelia de Lange's syndrome (CdLS) is a genetic disorder characterized by developmental disorders in several organ systems, including the brain, bones, digestion, immunity, endocrine, and others. This syndrome is mainly caused by mutations in the NIPBL, SMC3, and SMC1A genes. CdLS are generally comorbid with developmental or intellectual-level disorders, autism spectrum disorders, self-injury behavior, difficulty speaking, anxiety, hyperactivity, and sleep problems. This CdLS has a significant impact on the quality of life and maladaptive function in patients, as well as causing psychological disorders for families. Therefore, the need for psychiatric assistance for family psychoeducation, psycho-social interventions and cognitive-behavioral education.
Current Drug Repurposing Strategies in Treatment of
COVID-19
Authors: Kapoor Kapish , Sanawedwala Abbas , Rajput Deeksha , Bhardwaj Shreyansh , Shrivastav Kriti , Dhingra Naveen
Published: November 2020

Drug repurposing is the process of finding the new uses of existing drugs. It is one
of the emerging methods involved in selecting a molecule for diseases which are
communicable and can spread in the general population at a faster pace. The method is
selected over conventional drug discovery methods because it is a faster way to bring an
existing molecule for a different disease. Ever since COVID-19 pandemic has emerged
worldwide use of repurposed drugs has become an important toll to tackle this viral disease.
This review is a study of the varous stargegies of drug reprposing for the treatment of COVID19.
Studies on Drug Release Kinetics and Mechanism from
Sustained Release Matrix Tablets of Isoniazid using Natural
Polymer Obtained from Dioscorea Alata
Authors: Solanki Dharmendra , Motiwale Mohit
Published: November 2020

Sustained-release (SR) matrix tablets of Isoniazid and polysaccharide isolated from
tubers of Dioscorea alata, at different drug to polymer ratios, were prepared by using wet
granulation method. The formulated tablets were also characterized by physical and chemical
parameters and results were found in acceptable limits. The investigation focuses on the
influence of the proportion of the matrix material on the mechanism and the release rate of the
drug from the tablets. In vitro drug release appears to occur both by diffusion and a swellingcontrolled
mechanism, indicates the drug release from the tablet was non-Fickian super case II
transport. The drug release data fit well to the Korsmeyer equation.
Protein-protein Interaction Analysis of Contributing
Molecules in Dura mater Healing Process
Authors: Ban Bolly Hendrikus Masang , Hermanto Yulius , Faried Ahmad , Arifin Muhammad Zafrullah , Yembise Trajanus Laurens , Wirakusumah Firman Fuad
Published: November 2020

Background: Dura mater is a special tissue that fulfills a critical function in brain
anatomy and physiology. This tissue contains numerous cells, stem cells, and growth factors. This
research investigates the protein interaction contributing to dura mater healing process. Methods: We
use the available analysis software to perform the protein-protein interaction (PPI) analysis
(http://gpsprot.org/index.php). GPS Protein is an interactive platform for visualizing human protein
interaction by integrating HIPPIE and CORUM databases. We excluded HIV-1 proteomic and RNAi
databases, instead focused on human PPI (Confidence level 0.75). Two proteins were inputted as
query to identify the potential protein network in Dura mater healing according to previous studies,
i.e. fibroblast growth factor-2 (FGF2) and transforming growth factor beta-1 (TGFβ1). Results: PPI
results shows a high level (confidence level > 0.75) of protein-protein interaction of TGFβ1 to 197
other proteins (Confidence level ranges: 0.49 - 0.87), and PPI of FGF2 to 26 other proteins
(Confidence level ranges: 0.0-0.97). TGFβ1 interactions showed the important interactions to some
remodeling proteins. TGFβ1 encoded regulates cell proliferation, differentiation, growth, expression
modulation and the activation of other growth factors. It also induces epithelial-to-mesenchymal
transition (EMT) and cell migration. Conclusion: This bioinformatics approach is the more efficient
and cheaper method for analyzing the molecular aspect of protein that has a special contribution in
Dura mater healing process. These results could beneficial in focusing further researches for more
complex laboratory examinations.
Preparation and characterization of baicalein loaded
phytosomes: Assessment of in vitro parameters
Authors: Zade KanchanV , Jain Alok Pal
Published: November 2020

Phytosome is a complex between natural active ingredient and a phospholipid.
Further, phytosomes been applied to many popular herbal extracts or active molecules for
augmenting oral dissolution. Therefore, in present investigation, orally administered Baicalein,
atype of flavanoids, is poorly absorbed, and shows suboptimal dissolution. The phytosomes
encapsulating baicalein (1:1 Mm) were prepared by reverse phase evaporation method followed
by lyophilization. Transmission electron microscopy (TEM) analysis revealed that phytosomes
were almost spherical in shape with particle size below 100 nm. The Powder ex-ray diffraction
(PXRD) and differential scanning calorimetry (DSC) demonstrated that Baicalein loaded
phytosomes were amorphous in nature. Amorphization of therapeutic moiety leads to
improvement in dissolution. In conclusion, epigallocatechin loaded phytosomes exhibited
promising results and warrant further in vitro andin vivo investigations under a set of stringent
parameters for transforming in to a clinically viable products.
Dust Transport from Inland Australia and its Impact on Air Quality and Health on the Eastern Coast of Australia during the February 2019 Dust Storm.
Authors: Aragnou Emilie , Watt Sean , Nguyen Duc Hiep , Cheeseman Cassandra , Riley Matt , Leys John , White Stephen , Salter David , Azzi Merched , Tzu-Chi Chang Lisa , Morgan Geoffrey , Hannigan Ivan
Published: November 2020

Dust storms originating from Central Australia and western New South Wales frequently cause high particles concentration at many sites across New South Wales, both inland and along the coast. This study focussed on a dust storm event in February 2019 which affect air quality across the state as detected at many ambient monitoring stations in the Department of Planning, Industry and Environment (DPIE) air quality monitoring network. The WRF-Chem (Weather Research and Forecast Model – Chemistry) model is used to study the formation, dispersion and transport of dust across the state of New South Wales (NSW, Australia). Wildfires also happened in northern NSW at the same time of the dust storm in February 2019, and their emissions are taken into account in WRF-Chem model by using Fire Inventory from NCAR (FINN) as emission input. The model performance is evaluated and is shown to predict fairly accurate the PM2.5 and PM10 concentration as compared to observation. The predicted PM2.5 concentration over New South Wales during 5 days from 11 to 15 February 2019 is then used to estimate the impact of the February 2019 dust storm event on three health endpoints namely mortality, respiratory and cardiac diseases hospitalisation rates. The results show that even though as the daily average of PM2.5 over some parts of the state, especially in western and north western NSW near the centre of the dust storm and wild fires, are very high (over 900 µg/m3), the population exposure is low due to the sparse population. The top five Statistical Area Level 4 regions with the most impact in term of mortality, respiratory diseases hospitalisation and cardiac disease hospitalisation are Far West and Orana, Newcastle and Lake Macquarie, New England and North West, Sydney – Inner South West and either Central Coast (mortality) or Sydney – Parramatta (respiratory diseases hospitalisation) or Sydney – Inner West (cardiac diseases hospitalisation). Generally, the health impact is similar in order of magnitude to that caused by biomass burnings events from wildfires or from hazardous reduction burnings (HRBs) near populous centres such as in Sydney in May 2016. One notable difference is the higher respiratory diseases hospitalisation for this dust event (161) compared to fire event (24).
Online Multilingual Hate Speech Detection: Experimenting with Hindi and English Social Media
Authors: Vashistha Neeraj , Zubiaga Arkaitz
Published: November 2020

The exponential increase in the use of the Internet and social media over the last two decades has changed human interaction. This has led to many positive outcomes, but at the same time it has brought risks and harms. While the volume of harmful content online, such as hate speech, is not manageable by humans, interest in the academic community to investigate automated means for hate speech detection has increased. In this study, we analyse six publicly available datasets by combining them into a single homogeneous dataset and classify them into three classes, abusive, hateful or neither. We create a baseline model and we improve model performance scores using various optimisation techniques. After attaining a competitive performance score, we create a tool which identifies and scores a page with effective metric in near-real time and uses the same as feedback to re-train our model. We prove the competitive performance of our multilingual model on two langauges, English and Hindi, leading to comparable or superior performance to most monolingual models.
Ethylene Polymerization via Zirconocene Catalysts and Organoboron Activators: An Experimental and Kinetic Modeling Study
Authors: Valencia Luis , Enríquez-Medrano Francisco , López-González Ricardo , Quiñonez-Angulo Priscila , Saldívar-Guerra Enrique , Díaz-Elizondo José , Zapata-González Iván , Díaz de León Gómez Ramón
Published: November 2020

After 40 years of the discovery of metallocene catalysts, there are still several aspects that remain unresolved, especially when the “conventional” alkylaluminum activators are not used. Herein, we systematically investigate the synthesis of PE via three different zirconocene catalysts, with different alkyl substituents, activated via different organoboron compounds. The polymerization behavior, as well as the properties of the materials, are evaluated. The results demonstrate that the highest catalytic activity is shown by Bis(cyclopentadienyl)dimethylzirconium activated by trityl tetra(pentafluorophenyl)borate. Also finding that toluene is the optimum solvent for these systems and at these reaction conditions. Moreover, to validate our experimental results, a comprehensive mathematical model is developed on the basis of thermodynamic and kinetic principles. The concentration of ethylene transferred to the solvent phase (toluene) in a liquid-vapor equilibrium (LVE) system is estimated based on the Duhem’s theorem. Arrhenius expressions for the kinetic rate constants of a proposed kinetic mechanism are estimated by a kinetic model, in which the rate of polymerization is fitted by a least-square optimization procedure and the molecular weight averages by the method of moments. The simulations of the coordination polymerization suggest the presence of two types of active sites, principally at low temperatures, and the reactivation of the deactivated sites via a boron-based activator. However, the effect of the temperature on the reactivation step is no clear; a deeper understanding via designed experiments is required.
FRANSA VE AACHEN ANTLAŞMASI ÇERÇEVESİNDE AVRUPA ORDUSU ÇABALARI
Authors: AYHAN Halis
Published: November 2020

Avrupa Ordusu federalistlerin gözde tasarısıdır. Bu amaca gerek Birlik gerekse devletler düzeyinde ulaşılma gayreti sürmektedir. Birlik düzeyinde hem hukukî hem de askerî bazı altyapılar oluşturulmuştur. Avrupa Birliği Antlaşması’nda Ortak Güvenlik ve Savunma Politikası hükümleri hukuki; Avrupa Kolordusu ve AB Savaşöbekleri askerî; PESCO da proje altyapılarını oluşturmaktadır. Ancak mevcut şartlarda her iki askerî oluşum da NATO ile boy ölçüşebilir değildir.
Devletler düzeyinde ise ordu kurulması çabalarının başını Fransa çekmektedir. Almanya ile imzaladığı Aachen Antlaşması savunma ve güvenlik hükümleri içermektedir. Merkel amacın Avrupa Ordusu’na ulaşmak olduğunu resmen belirtmiştir. ABD ve NATO’nun karşı çıkması, AB içinde kutuplaşmalar ordunun önündeki en büyük engellerdir. Fransa’daki Sarı Yelekliler isyanı ordu fikriyle bağlantılıdır ve olayların Fransa’da patlak vermesinin sebeplerinden biri de budur. Çalışmanın kapsamı Avrupa Ordusu girişimlerinin Fransa temelli incelenmesidir.
ANTROPOLOJİNİN BARIŞ OPERASYONLARININ BAŞARISINA ETKİSİ: SURİYE ANALİZİ
Authors: EMİNOĞLU Ayça , YILMAZ Hasan
Published: November 2020

Bu çalışmanın amacı, “Barış müdahalelerinin başarısına antropolojik değerlendirmeler ne oranda katkı sağlayabilmektedir?” sorusuna, ‘hibrit’ (melez) barış inşasına bakarak yanıt aramaktır. Alan yazın taraması neticesinde ortaya çıkarılan bulguların, Suriye iç savaşı vaka analizinde teyidine çalışılmıştır. Antropolojik çalışmaların hibrit barış inşasında uygulanmasının barış girişimlerine katkı sağlayacağı hipotezinden hareket edilmiştir. Yerelde günlük barışın sağlanmasına katkı sağlayan sivil toplum faaliyetlerince kullanılan antropolojik yaklaşımın, yerelde barışın icrasında görev yapan silahlı kuvvetlerce kullanılamadığı düşünülmektedir. Siyasi müzakereler seviyesinde (ulusal ve uluslararası) ise, ‘yüksek politikalar’ nedeniyle antropolojik yaklaşımların kabul edilebilirliğinin düşük olduğu gözlemlenmektedir. Suriye iç savaşı, sivil toplumun (yerel taban örgütlenmeleri ve hükümet dışı oluşumlar) günlük barışa etkin katkı sağlaması, benzer başarının siyasi müzakereler seviyesinde ve yüksek politikaların emrinde olan silahlı kuvvetlerce elde edilememesi olgusuyla bu bulguları teyit eder niteliktedir.
Разработка вакцины против коронавирусной инфекции на базе норовирусной молекулярной платформы
Authors: Новиков Дмитрий , Мохонов Владислав , Мохонова Екатерина , Лапин Владислав , Мелентьев Дмитрий , Новиков Виктор
Published: November 2020

Известно, что белок норовируса VP1 способен самостоятельно собираться в вирусоподобные частицы (ВПЧ), на которые развивается достаточно сильный иммунный ответ. Нами получен рекомбинантный VP1 эпидемического варианта норовируса генотипа GII.4, доминировавшего на территории Нижегородской области в 2018 г. Показана способность VP1 к самосборке, его безопасность и иммуногенность. ВПЧ на основе VP1 норовируса использованы в качестве молекулярной платформы для разработки вакцины против коронавирусной инфекции. Для этого проведена замена части белка VP1, экспонированной на поверхности ВПЧ, на аминокислотную последовательность SARS-CoV-2, кодирующую сайты связывания с рецепторами (RBD). Для увеличения растворимости и корректного фолдинга N-концевая часть рекомбинантной химеры VP1 норовируса с RBD SARS-CoV-2 слита с периплазматическим мальтозосвязывающим белком E.coli с включением сайта для специфичного гидролиза. Проведена оптимизация экспрессии, растворения и очистки слитого белка VP1 норовируса с RBD SARS-CoV-2. Полученная химерная структура может быть использована в составе вакцины для профилактики COVID-19, применимой для интраназальной вакцинации.
ARE ISLAMIC BANKS SUFFERING FROM A MODEL MISFIT? COMPARISON WITH COOPERATIVE BANKS
Authors: Gulzar Rosana , Ibrahim Mansor H. , Ariff Mohamed
Published: November 2020

For the first time, this study investigates whether Islamic banks, in mimicking conventional banks, have become less stable than their theoretical equivalent, which is the cooperative banks in Europe. Theoretically the interest prohibition should have pushed Islamic banks towards mutuality and profit-sharing, which have been argued to be stabilising. In practice however, the banks are pushed for growth under a debt-driven commercial banking model which is not only antithetical to the Shariah but also destabilising. This may explain why the empirical findings are still divergent in Islamic banking stability studies. Our study employs system GMM to compare the stability of 37 Islamic banks against 1,536 cooperative banks in Europe during the 2008 crisis and post-non-crisis years. Interestingly, we found consistent and significant evidence that the Islamic banks are less stable than the cooperative banks in both macroeconomic conditions. This has significant policy implications, main of which is to steer reform efforts away from refurbishing Islamic commercial banks and towards building an entirely new Islamic cooperative bank, based on the model in Europe.
ISLAMIC VS CONVENTIONAL FUNDS WITHIN THE FAMILY: SELECTIVITY SKILLS AND MARKET TIMING ABILITY
Authors: Bani Atta Anas Ahmad , Marzuki Ainulashikin
Published: November 2020

ABSTRACT
The aim of the study is to compare the performance of Islamic mutual fund (IMF) and conventional mutual fund (CMF) within the same family, in addition, to examine the performance of fund family in Malaysia for the period from 2007 to 2018. The study used eight measures of performance, raw returns, excess returns, Sharpe ratio, Treynor ratio, Jensen alpha, Carhart four-factor model as selectivity models, In addition to Treynor & Mazuy (TM) and Hendrickson & Merton (HM) as market timing models. The study contributes by investigating and compares the performance at the family level. The results reported that IMFs exhibited some fund selection ability over CMFs. However, both types of funds displayed poor market timing ability. At a fund family level, the results show the fund families exhibited good fund selections skills, at the same time, fund family still exhibited poor market timing ability. The novel result of this study that the difference in performance between Islamic and conventional funds shrank compared to the results of previous studies. Due to the common advantages offered by the families for both types of funds. The findings are important to investors because the results provide new evidence about the fund families' performance. Most investors follow the top-down approach, where mutual fund investors initially choose fund families before deciding which funds to hold. In addition, the results are important for managers to decide which types of funds that they may issue in their own families, so that they can perform well in the future.
ACCEPTANCE OF ISLAMIC EQUITY-BASED MORTGAGE PRODUCT: AN EXTENSION OF DECOMPOSED THEORY OF PLANNED BEHAVIOUR
Authors: Shaikh Imran Mehboob , Noordin Kamaruzaman
Published: November 2020

This study examine the determinants that may predict the consumer’s intention to accept equity-based product, which is mushārakah mutanāqisah (MM) Islamic mortgage. Survey was conducted using multi-stage and purposive sampling. For the purpose of analysis structural equation modelling technique was used in current research. Moreover, 306 responses were gathered from users of MM Islamic mortgage. The theoretical framework of the current study was drawn upon the decomposed theory of planned behaviour (DTPB) because of its predictive power and robustness to base a model. The findings of the study revealed that behavioural intention appeared to have been directly and indirectly influenced by all constructs and above all most significant factors are Peers and perceived behaviour control. All the main beliefs, namely, attitude, subjective norm, perceived behaviour control, which are predicted by compatibility, relative advantage, peers and self-efficacy affects consumers’ intention to accept mushārakah mutanāqisah, MM home financing. The effect of pricing variable on intention was significant as well. Pricing variable is yet to be tested therefore, this paper will be a useful reference for the policymakers, academicians and future researchers.
ISLAMIC FINANCIAL DEVELOPMENT AND ECONOMIC GROWTH IN NIGERIA: A BOUNDS TESTING APPROACH
Authors: Sabiu Tasiu Tijjani , Abduh Muhammad
Published: November 2020

Using a bounds testing approach to the cointegration and error correction method developed within the autoregressive distributed lag (ARDL) framework, this paper analyses the short- and long-run dynamic relationships between Islamic financial development and economic growth in Nigeria. Quarterly time-series data (2012:1 to 2019:3) are employed for the variables, together with non-interest bank financing to the private sector and real gross domestic product as indicators of Islamic financial development and economic growth respectively. The results indicate a significant short- and long-run relationship between Islamic financial development and economic growth. The relationship, however, is neither Schumpeter’s supply-leading nor Robinson’s demand-following type; rather, it appears to be bi-directional. In addition, empirical evidence is found that underscores the important role of Islamic bank financing in the economic performance of Nigeria. The paper recommends that improvement of the Islamic financial system in Nigeria may foster economic development and enhance welfare and poverty alleviation in the long run.