bluuebunny/crossref_metadata_2025 huggingface dataset:
FUNCTIONAL OUTCOME OF TOTAL HIP ARTHROPLASTY WITH DUAL MOBILITY CUPS IN HIP ARTHRITIS-A PROSPECTIVE COHORT STUDY
Authors:   Clinical Associate, Apollomedics Hospital Lucknow DNB Orthopaedic Surgery., Vatsa Abhinav , Sohail Siddique Mohammed ,   Fellow Arthroplasty and Arthroscopy, Apollomedics Hospital, Lucknow, DNB Orthopaedic surgery, MNAMS., Chhutani Devashish ,   Associate Consultant, Apollomedics Hospital, Lucknow Former Senior Registrar AIIMS New Delhi M.S. Orthopaedics (MGM Medical College, Indore (M.P.).
Published: April 2024

Background: Dual mobility (DM) total hip arthroplasty (THA) has gained popularity due to its potential to enhance stability and reduce dislocation rates compared to traditional THA constructs. However, there is a need for further investigation into its functional outcomes, complications, and implant survivorship. Method: We conducted a hospital-based prospective study involving 50 patients undergoing total hip replacement over a one-year period. Functional outcomes were assessed using the Harris Hip Score (HHS) and Posterior Muscle Endurance (PME) Score. Descriptive statistics were used for data analysis. Results: The study population consisted predominantly of older patients (mean age 64.30 years), with a higher representation of males (56%). The most common diagnosis was neck of femur fracture (NOF#) (75%), with a balanced distribution of cemented (40%), uncemented (40%), and hybrid (20%) fixation techniques. HHS and PME scores showed significant improvements over 12 months, with excellent outcomes observed in 61.1% of participants. Complications occurred in 14% of patients, with peri-prosthetic fracture and surgical site infection being the most common. Implant survivorship at final follow-up was 94%. Conclusion: Dual mobility cup total hip replacement demonstrates promising outcomes in terms of functional improvement, low complication rates, and high implant survivorship. It represents a viable option for patients undergoing THA, particularly those at risk of dislocation. Further research, including prospective comparative studies, is needed to better understand its long-term efficacy and suitability across different patient populations.
Esquada e sua correlação com os marcadores de alimentação em inquérito de saúde: Evidências de validade
Authors: Costa e Silva Danilla Michelle , Santos Thanise Sabrina Souza , Slater Betzabeth
Published: April 2024

Objetivou-se avaliar a correlação entre ESQUADA e marcadores de alimentação saudável e não saudável. Trata-se de estudo psicométrico realizado com adultos participantes do Inquérito de Saúde de Base Populacional nos municípios de Teresina e Picos. A ESQUADA foi utilizada para avaliar a qualidade da dieta, mensurada em escores e classificada em cinco níveis de qualidade variando de “muito ruim” a “excelente”. Hábitos alimentares foram investigados com marcadores de alimentação saudável e não saudável. As frequências de consumo obtidas a partir dos marcadores e da descrição dos níveis de qualidade da dieta foram ordenadas em categorias, tornando-as postos comparáveis. O coeficiente de correlação por postos de Kendall foi utilizado no estudo de correlação entre as frequências, adotando-se a significância de 5%. Quanto melhor a qualidade da dieta, segundo a ESQUADA, mais saudável a alimentação dos indivíduos, segundo os marcadores. Foram observadas concordâncias variando de 53% (hortaliças cozidas) a 62,5% (frutas e bebidas açucaradas). A análise da concordância soma evidências de validade da ESQUADA e endossa seu uso em inquéritos de saúde permitindo a avaliação da qualidade da dieta em consonância com o guia alimentar para a população brasileira.
Yanya Mebusu ve Şura-yı Devlet Azası Ali Naki Paşa (1844-1904)
Authors: Olgun Said
Published: April 2024

Bu çalışmanın konusunu Yanya Mebusu Ali Naki Paşa oluşturmaktadır. Tanzimat Fermanının ilanından kısa bir süre sonra 1844 yılında Yanya’ya bağlı Libohova’da doğmuştur. Köklü ve zengin bir aile olan Arslan Paşazade ailesine mensuptur. Özel hocalardan temel düzeyde eğitim almıştır. Ali Naki Paşa, ailesinin sahip olduğu nüfuz ve Osmanlı saltanatına sadakati nedeniyle mebusluk ve Şura-yı Devlet üyeliği gibi çeşitli ve önemli vazifelerde bulunmuştur. Üstlenmiş olduğu görevlerde göstermiş olduğu başarılar hem hükümet hem de Padişah tarafından takdirle karşılanmıştır. Bilhassa II. Abdülhamid döneminde hızlı bir gelişim gösteren Arnavut ulusçuluğuna mesafeli durmaya özen göstermiştir buna rağmen şüpheci gözlerden korunması mümkün olmamıştır. İyi eğitim almalarını sağladığı çocukları Osmanlı devlet hizmetinde önemli görevler üstlendikleri gibi 1912 yılında kurulan Arnavutluk devletinde de önemli vazifelerde bulunmuşlardır.

Çalışmada bilhassa Osmanlı arşiv belgelerinden istifade edilerek Ali Naki Paşa’nın kronolojik bir hayat hikayesi ortaya konulmaya çalışılmıştır. Çeşitli başlıklar altında ailesi, ilk gençlik yıllarında yer aldığı görevler, mebusluğu, mutasarrıflığı, Şura-yı Devlet Azalığı ve çocukları hakkında bilgiler aktarılmıştır.
Application of Silicon Nanowires
Authors: Feng Yang , Zhao Shihua , Liang Ping , Xia Ziwen , Peng Hongyan
Published: April 2024

:

Silicon Nanowires (SiNWs), a novel category of nanomaterials, exhibit several outstanding
properties, including superior transistor performance, quantum tunneling effects, and
remarkable electrical and optical capabilities. These properties are expected to contribute significantly
to the development of future nanodevices, such as sensors and optoelectronic components.
The potential for device miniaturization with SiNWs is based on their ease of monocrystallization.
This leads to a reduced rate of hole-electron complexes and their extensive specific
surface area that promotes boundary effects, thereby diminishing conductivity. Characterized by
unique structural attributes, SiNWs hold promise for a wide range of applications in various
sectors. To date, multiple methods have been established for SiNW fabrication, including solgel,
electrochemical, laser ablation, chemical vapor deposition, and thermal vapor deposition
techniques. Subsequently, the focus has shifted to the application of SiNWs in electronics, energy,
and biomedicine. SiNWs are instrumental in producing high-performance electronic devices,
such as field-effect transistors, sensors, and memory units. They also exhibit outstanding photovoltaic
properties, making them suitable for high-efficiency solar cell and photocatalyst production.
Additionally, SiNWs are poised to make significant contributions to biomedicine, particularly
in biosensors, drug delivery systems, and tissue engineering materials. This article provides
a concise review of the current status of SiNWs in electronics, sensing devices, and solar cell
applications, and their roles in high-performance transistors, biosensors, and solar cells. It concludes
with an exploration of the challenges and prospects for SiNWs.

:

In summary, the unique attributes of SiNWs establish them as a versatile nanomaterial with
broad applicability. This review offers a comprehensive overview of SiNW research and theoretical
insights that may guide similar studies. The insights into recent SiNW research presented
here are intended to inform future applications and investigations involving these nanomaterials.
Lelylijn voor meer brede welvaart
Authors: van Dijk Jouke
Published: April 2024

Al meer dan dertig jaar zijn er plannen voor de aanleg van een spoorverbinding van Amsterdam via Lelystad en Heerenveen naar Groningen die stranden op politieke onwil en op verkeerde aannames over de kosten en baten. Op basis van de bijdrage aan de regionale en nationale Brede Welvaart kan het wel.
Luchtvervuiling in Vlaanderen
Authors: Van Acker Emma , Loopmans Maarten
Published: April 2024

Vlaanderen vormt een van de hotspots van luchtvervuiling in Europa. De hoge bevolkingsdichtheid, het dichte wegennetwerk en het hoge aandeel vervuilende dieselwagens maken er het wegverkeer een belangrijke bron van vervuiling. De Vlaming is terecht ongerust over de luchtkwaliteit. Dat er onder Vlamingen grote verschillen in blootstelling bestaan, is minder geweten.
EFEKTIVITAS LKPD DIGITAL BERBASIS PROBLEM BASED LEARNING TERHADAP KETERAMPILAN BERPIKIR KRITIS PESERTA DIDIK PADA MATERI SISTEM EKSKRESI KELAS XI DI SMA NEGERI 1 PANGKALPINANG
Authors: Shafira Istu Hanan
Published: April 2024

Penelitian ini bertujuan untuk mengetahui efektivitas LKPD digital berbasis Problem Based Learning terhadap keterampilan berpikir kritis peserta didik kelas XI di SMA Negeri 1 Pangkalpinang. Jenis penelitian berupa kuasi eksperimen dengan menggunakan  nonequivalent control group design. Populasi dalam penelitian ini adalah seluruh peserta didik kelas XI MIPA di SMA Negeri 1 Pangkalpinang. Sampel penelitian yang diambil sebanyak dua kelas yaitu kelas XI MIPA 4 sebagai kelas eksperimen dan kelas XI MIPA 1 sebagai kelas kontrol. Pemilihan sampel tersebut menggunakan teknik purposive sampling. Data keterampilan berpikir kritis dikumpulkan menggunakan tes berbentuk uraian. Analisis data dilakukan dengan uji Independent Sample T-test dan uji Effect Sizes.  Hasil penelitian menunjukkan bahwa penggunaan LKPD digital berbasis Problem Based Learning memberikan pengaruh yang signifikan terhadap keterampilan berpikir kritis peserta didik didasarkan pada hasil Independent T-test nilai Sig (2-tailed) sebesar 0,021 0,05. LKPD digital berbasis Problem Based Learning cukup efektif untuk meningkatkan keterampilan berpikir kritis peserta didik dengan nilai cohen’s d sebesar 0,6 yang termasuk dalam kategori sedang dengan persentase sebesar 73%.  Hal ini bermakna bahwa peseta didik cukup maksimal mencapai target keterampilan berpikir kritis dengan menggunakan LKPD digital berbasis Problem Based Learning dalam pembelajarannya.
PENGARUH MODEL INKUIRI TERBIMBING BERBANTUAN MEDIA VIDEO ANIMASI TERHADAP MINAT BELAJAR SISWA PADA MATERI SISTEM REPRODUKSI KELAS XI MIPA DI SMAN UMBULSARI JEMBER
Authors: Wulandari Ayu , Setyawati Heni
Published: April 2024

Keterlibatan dan partisipasi siswa dalam proses pembelajaran belum menunjukkan keaktifan siswa. Siswa cenderung kurang antusias dan proaktif dalam mengikuti pembelajaran. Inovasi yang dapat dilakukan agar siswa tertarik dan aktif dalam pembelajaran adalah diterapkan model pembelajaran inkuiri terbimbing berbantuan media video animasi. Tujuan dari penelitian ini yaitu: 1) Mengetahui minat belajar siswa kelas eksperimen setelah diberikan pembelajaran dengan model pembelajaran inkuiri terbimbing berbantuan media video animasi terhadap minat belajar siswa pada materi sistem reproduksi kelas XI MIPA di SMA Negeri Umbulsari Jember tahun pelajaran 2022/2023. 2) Mengetahui pengaruh model pembelajaran inkuiri terbimbing berbantuan media video animasi terhadap minat belajar siswa pada materi sistem reproduksi kelas XI MIPA di SMA Negeri Umbulsari Jember tahun pelajaran 2022/2023. Pendekatan yang digunakan penelitian ini adalah pendekatan kuantitatif dengan jenis Quasi Experiment dengan bentuk Nonequivalent Group Control Pretest Posttest Design. Pada design ini terdapat dua kelompok yaitu kelompok eksperimen dan kelompok kontrol yang diberi pretest dan posttest. Pengambilan sampel dilakukan dengan teknik purposive sampling. Teknik analisis data yang digunakan adalah uji Z. Hasil penelitian menunjukkan: 1) Minat belajar siswa kelas eksperimen memperoleh skor rata-rata 53,21 saat pretest dan 57,74 saat posttest, nilai tersebut lebih tinggi daripada kelas kontrol yang mempunyai nilai rata-rata sebesar 52,91 saat pretest dan 53,44 saat posttest. 2)Terdapat pengaruh yang signifikan model pembelajaran inkuiri terbimbing berbantuan media video animasi terhadap minat belajar siswa pada materi sistem reproduksi kelas XI MIPA di SMA Negeri Umbulsari Jember tahun pelajaran 2022/2023 dengan nilai signifikansi 0,000. Penelitian ini diharapkan dapat menjadi alternatif pembelajaran yang dapat digunakan oleh guru untuk meningkatkan keterampilan berpikir siswa.
Identifying X (Formerly Twitter) Posts Relevant to Dementia and COVID-19: Machine Learning Approach
Authors: Azizi Mehrnoosh , Jamali Ali Akbar , Spiteri Raymond J
Published: April 2024

Background

During the pandemic, patients with dementia were identified as a vulnerable population. X (formerly Twitter) became an important source of information for people seeking updates on COVID-19, and, therefore, identifying posts (formerly tweets) relevant to dementia can be an important support for patients with dementia and their caregivers. However, mining and coding relevant posts can be daunting due to the sheer volume and high percentage of irrelevant posts.

Objective

The objective of this study was to automate the identification of posts relevant to dementia and COVID-19 using natural language processing and machine learning (ML) algorithms.

Methods

We used a combination of natural language processing and ML algorithms with manually annotated posts to identify posts relevant to dementia and COVID-19. We used 3 data sets containing more than 100,000 posts and assessed the capability of various algorithms in correctly identifying relevant posts.

Results

Our results showed that (pretrained) transfer learning algorithms outperformed traditional ML algorithms in identifying posts relevant to dementia and COVID-19. Among the algorithms tested, the transfer learning algorithm A Lite Bidirectional Encoder Representations from Transformers (ALBERT) achieved an accuracy of 82.92% and an area under the curve of 83.53%. ALBERT substantially outperformed the other algorithms tested, further emphasizing the superior performance of transfer learning algorithms in the classification of posts.

Conclusions

Transfer learning algorithms such as ALBERT are highly effective in identifying topic-specific posts, even when trained with limited or adjacent data, highlighting their superiority over other ML algorithms and applicability to other studies involving analysis of social media posts. Such an automated approach reduces the workload of manual coding of posts and facilitates their analysis for researchers and policy makers to support patients with dementia and their caregivers and other vulnerable populations.
A Self-Guided Web-Based App (MyDiaMate) for Enhancing Mental Health in Adults With Type 1 Diabetes: Insights From a Real-World Study in the Netherlands
Authors: Embaye Jiska , de Wit Maartje , Snoek Frank
Published: April 2024

Background

MyDiaMate is a web-based intervention specifically designed for adults with type 1 diabetes (T1D) that aims to help them improve and maintain their mental health. Prior pilot-testing of MyDiaMate verified its acceptability, feasibility, and usability.

Objective

This study aimed to investigate the real-world uptake and usage of MyDiaMate in the Netherlands.

Methods

Between March 2021 and December 2022, MyDiaMate was made freely available to Dutch adults with T1D. Usage (participation and completion rates of the modules) was tracked using log data. Users could volunteer to participate in the user profile study, which required filling out a set of baseline questionnaires. The usage of study participants was examined separately for participants scoring above and below the cutoffs of the “Problem Areas in Diabetes” (PAID-11) questionnaire (diabetes distress), the “World Health Organization Well-being Index” (WHO-5) questionnaire (emotional well-being), and the fatigue severity subscale of the “Checklist Individual Strength” (CIS) questionnaire (fatigue). Two months after creating an account, study participants received an evaluation questionnaire to provide us with feedback.

Results

In total, 1008 adults created a MyDiaMate account, of whom 343 (34%) participated in the user profile study. The mean age was 43 (SD 14.9; 18-76) years. Most participants were female (n=217, 63.3%) and higher educated (n=198, 57.6%). The majority had been living with T1D for over 5 years (n=241, 73.5%). Of the study participants, 59.1% (n=199) of them reported low emotional well-being (WHO-5 score≤50), 70.9% (n=239) of them reported elevated diabetes distress (PAID-11 score≥18), and 52.4% (n=178) of them reported severe fatigue (CIS score≥35). Participation rates varied between 9.5% (n=19) for social environment to 100% (n=726) for diabetes in balance, which opened by default. Completion rates ranged from 4.3% (n=1) for energy, an extensive cognitive behavioral therapy module, to 68.6% (n=24) for the shorter module on hypos. There were no differences in terms of participation and completion rates of the modules between study participants with a more severe profile, that is, lower emotional well-being, greater diabetes distress, or more fatigue symptoms, and those with a less severe profile. Further, no technical problems were reported, and various suggestions were made by study participants to improve the application, suggesting a need for more personalization.

Conclusions

Data from this naturalistic study demonstrated the potential of MyDiaMate as a self-help tool for adults with T1D, supplementary to ongoing diabetes care, to improve healthy coping with diabetes and mental health. Future research is needed to explore engagement strategies and test the efficacy of MyDiaMate in a randomized controlled trial.
Evaluating the User Experience of a Smartphone-Delivered Sexual Health Promotion Program for Older Adults in the Netherlands: Single-Arm Pilot Study (Preprint)
Authors: Correia de Barros Ana , Bergmans Mariëtte , Hasanaj Kreshnik , Krasniqi Drianë , Nóbrega Catarina , Carvalho Carneiro Bruna , Vasconcelos Priscila A , Quinta-Gomes Ana Luísa , Nobre Pedro J , Couto da Silva Joana , Mendes-Santos Cristina
Published: April 2024

BACKGROUND

Sexual health is an important component of quality of life in older adults. However, older adults often face barriers to attaining a fulfilling sexual life because of issues such as stigma, lack of information, or difficult access to adequate support.

OBJECTIVE

We aimed to evaluate the user experience of a self-guided, smartphone-delivered program to promote sexual health among older adults.

METHODS

The mobile app was made available to community-dwelling older adults in the Netherlands, who freely used the app for 8 weeks. User experience and its respective components were assessed using self-developed questionnaires, the System Usability Scale, and semistructured interviews. Quantitative and qualitative data were descriptively and thematically analyzed, respectively.

RESULTS

In total, 15 participants (mean age 71.7, SD 9.5 years) completed the trial. Participants showed a neutral to positive stance regarding the mobile app’s usefulness and ease of use. Usability was assessed as “Ok/Fair.” The participants felt confident about using the mobile app. To increase user experience, participants offered suggestions to improve content and interaction, including access to specialized sexual health services.

CONCLUSIONS

The sexual health promotion program delivered through a smartphone in a self-guided mode was usable. Participants’ perception is that improvements to user experience, namely in content and interaction, as well as connection to external services, will likely improve usefulness and acceptance.
Artificial Intelligence-Based Mobile Phone Applications for Child Mental Health: A Systematic Review and Content Analysis (Preprint)
Authors: Yang Fan , Wei Jianan , Zhao Xuejun , An Ruopeng
Published: April 2024

BACKGROUND

Mobile phone apps powered by Artificial Intelligence (AI) have emerged as powerful tools to address mental health challenges faced by children. This study aimed to comprehensively review AI-driven apps for child mental health, assessing their availability, quality, readability, characteristics, and functions.

OBJECTIVE

This study aimed to comprehensively review AI-driven apps for child mental health, assessing their availability, quality, readability, characteristics, and functions.

METHODS

Utilizing a systematic review approach, we initially identified 369 apps, which, after screening eligibility, resulted in 27 apps being included in this study. Quality was evaluated using the Mobile Application Rating Scale (MARS). A readability calculator was implemented to assess readability by utilizing the count of words, syllables, and sentences to generate a score indicative of the reading difficulty level. Content analysis was conducted to evaluate the apps’ availability, characteristics, and functionality.

RESULTS

Evaluation of the apps revealed three functional categories: chatbot (15 apps), journal logging (9 apps), and psychotherapeutic treatment (3 apps). A majority (74.1%) employed natural language processing technology. The average MARS score of 3.45 out of 10 demonstrated a need for quality improvement. Low readability (averaged 6.04 for the content and 9.44 for the introduction in the app store) and monotonous user interface implied inadequate child-friendly design. While 74.1% of apps used clinically validated technologies, rigorous clinical tests of the apps were often missing, with only one app undergoing a clinical trial. Concerns over response accuracy were also identified. High costs (74.1% required payment with a mean of $20.16/month) could also limit accessibility.

CONCLUSIONS

This study highlighted an urgent need for improved quality, child-friendly design, rigorous clinical testing, and affordable pricing to maximize the benefits of these AI-based mental health apps for children.
Investigating Antecedents to Older Adults’ Uptake of Health Information Systems: Case of Electronic Personal Health Records (Preprint)
Authors: Torkman Reza , Ghapanchi Amir Hossein , Ghanbarzadeh Reza
Published: April 2024

BACKGROUND

Although older adults are most in need of utilizing health information systems such as electronic Personal Health Records (PHR), existing literature has given poor attention to this vulnerable group of users.

OBJECTIVE

The current study aimed to understand the determinants of the intention to use electronic Personal Health Record (PHR) systems among elderlies.

METHODS

Hands-on workshops were organised to clarify various functions of a PHR system for 135 seniors and increase their knowledge of using the system for self-management of their chronic conditions. After the completion of the training, a survey was conducted to evaluate the usage intention toward PHR through the lens of Health Belief Model (HBM). The data were analysed using Partial Least Squares (PLS) path modelling.

RESULTS

Data analysis of 135 responses received uncovered that the seniors’ usage intention toward the PHR is a function of PHR’s perceived usefulness, perceived barriers, perceived confidence, and cues to action. Of these, perceived usefulness was found to be the strongest predictor. The results also indicated that perceived susceptibility and perceived severity do not significantly impact the seniors’ intention for the PHR.

CONCLUSIONS

According to the findings and based on the HBM literature, if individuals perceive more benefits and fewer barriers to the PHR, greater self-efficacy, and better cues to action, they are more likely to adopt the system.

CLINICALTRIAL

N/A
Correction: Investigating Father or Partner Involvement in Family Integrated Care in Neonatal Units: Protocol for a Prospective, Multicenter, Multiphase Study (Preprint)
Authors: Rubinstein Rupa , Gallagher Katie , Ho John , Bose Julian , Khashu Minesh , Aladangady Narendra
Published: April 2024

UNSTRUCTURED
The effect of curcumin-piperine co-supplementation on kidney allograft function in kidney transplant recipients: study protocol for a double-blind, randomized, controlled trial (Preprint)
Authors: Nosrati-Oskouie Mohammad
Published: April 2024

UNSTRUCTURED

Kidney transplant recipients (KTRs) are at high risk of vascular dysfunction and delayed graft function. The current study presents a protocol for an interventional clinical trial to survey the hypothesis, that curcumin-piperine co-supplementation is effective in improving kidney allograft function and can reduce inflammation and vascular complication in KTR.
The study is randomized, double-blind, and placebo-controlled, with two parallel arms that will include a total of forty KTRs. KTRs aged 18-60 years will be randomized in a ratio of 1:1 to receive either curcumin-piperine (500 mg curcumin and 5 mg piperine) or a matching placebo (505 mg maltodextrin) for 12 weeks immediately after kidney transplantation (time 0) and week 12. The primary outcome is to evaluate the immediate, delayed, and slow graft function, serum creatinine, and eGFR. The secondary outcomes are glycemic control, lipid profile, length of hospital day, duration of DGF, number and dosage of immunosuppressive drugs, and inflammation.
This study is the first randomized clinical trial based on our knowledge to assess the effect of curcumin-piperine co-supplementation on kidney allograft function in KTRs. Curcumin supplementation may be effective in increasing graft function by reducing inflammation and oxidative stress.
Trial registration: This trial has been registered in the Iranian Registry of Clinical Trials (IRCT) with code “IRCT20110123005670N29”, https://en.irct.ir/trial/63535. The registration date is June 22, 2022.
JiXiao Glaze Online Store Operation and Promotion Strategy to Discuss
Authors: Song Guohua , Yan Hao , Bo Naiwen , Ming Qiaoying
Published: April 2024

The rapid development of Internet technology, so that many merchants have to take advantage of the e-commerce platform audience to carry out the online business, although achieved a certain sales effect, but not ideal, the main reason is that the operation and promotion strategy of the online store is not in-depth study. Online store only find in line with their own operation and promotion strategy, in order to form their own radiation effect, and ultimately realize the operational goals. This study discusses the operation and promotion strategy of Liuli online store in depth, hoping that the operators can change their thinking and flexibly apply various operation and promotion strategies of online store according to the specific situation, so as to promote the good operation and development of online store. It is hoped that this study can provide reference for online store operators.
An Institution-Based Ethics Review Committee Model for Research on Human Subjects in Eswatini: Composition, Duties and Operations
Authors: Dlamini Sabelo V. , Babazile Shongwe , Sihle Nxumalo
Published: April 2024

It is becoming increasing apparent that Universities in Eswatini need to establish effective ethics review committees to review applications from students and from faculty researchers. As the establishment of postgraduate programmes continue to increase, the volume of applications expected to be reviewed by the national Eswatini Human and Health Research Review Board (EHHRRB) continue to increase. The capacity of the EHHRRB is in itself not adequate for the load. High load of reviews suggest that not enough time is spent on each application. Hence universities have to carry some of this burden by reviewing their student applications or even applications from researchers in the country. It has been observed that universities themselves have either poorly constituted ethics committees or ones that are non-functional. This paper attempts to review different models of university-based committees that may be adopted by universities in Eswatini. Three models are discussed, the single central committee model, the devolved committee model and the rotating committee models. The paper discusses strengths and weaknesses of each model. The rotating committee model encapsulates the strengths of the former two models while suggesting how this model may avoid their weaknesses. The paper does not in any way entail to prescribe any model for any university but merely elucidates on the pros and cons of each in order to assist universities make informed decisions on which model best suites their set up.
REVIEW OF THERMODYNAMIC AND PHYSICO-CHEMICAL PARAMETERS INFLUENCING METHYLENE BLUE ADSORPTION ON ACTIVATED CHARCOAL OF NATURAL ORIGIN
Authors: BALDE MAMADOU , DIEDHIOU ADAMA , NDOYE IDRISSA , TIRERA HAROUNA , GUEYE ROKHAYA SYLLA , TINE YORO , THIAM KHADIDIATOU , GUEYE NANGO , SECK MATAR , FALL DJIBRIL , WELE ALASSANE
Published: April 2024

Methylene blue (MB) is a phenothiazine derivative used in microbiology, surgery, diagnostics and as a sensitizer in the photo-oxidation of organic pollutants. These numerous uses of methylene blue could lead to its accumulation in wastewater, causing harmful effects on the environment and living beings. To combat these harmful effects, numerous wastewater treatment processes, particularly physicochemical, were implemented. Adsorption techniques are particularly used to find new natural, biodegradable and inexpensive adsorbents to treat colored waste from structures such as medical and pharmaceutical laboratories. The aim of the present study was to carry out a relevant bibliographical review of the physico-chemical and thermodynamic parameters that can influence this adsorption of methylene blue on activated carbons of natural origin. The results showed a remarkable elimination of methylene blue. However, parameters such as particle size, adsorbent mass, pH, contact time, initial methylene blue concentration, agitation speed and temperature showed that the adsorption capacity of MB on biosorbents was influenced by these quantities. Similarly, the positive and negative enthalpy values (ΔH°) indicated that adsorption process could be endothermic or exothermic. Other thermodynamic parameters, such as the negative value of Gibbs free energy (ΔG°) and the positive value of entropy (ΔS°), also showed that the adsorption process was feasible and spontaneous.
TANDEM MASS SPECTROMETRIC METHOD FOR THE TRACE LEVEL DETERMINATION OF 2-AMINOPYRIDINE: A POTENTIAL GENOTOXIC IMPURITY IN TENOXICAM API
Authors: RATHORE MANOJ KUMAR , MOHAN REDDY T. RAMA
Published: April 2024

Objective: This study aimed to develop a highly sensitive method for the determination of the genotoxic impurity 2-amino pyridine in Tenoxicam, employing hyphenated techniques.
Methods: The determination of 2-amino pyridine was carried out using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method in Selected Ion Monitoring mode (SIM). A LiChrospher RP-18 (100×4.6 mm) 5.0 µm column was utilized for the separation. A gradient elution technique was employed with acetonitrile (mobile phase A) and 0.01M ammonium acetate buffer (mobile phase B) in varying ratios. The gradient program (T/%B) was set as 0/5, 2.50/15, 5.00/30, 10.00/50, 15.00/95, 20.00/95. The developed method was validated according to the International Conference on Harmonization guidelines.
Results: The limits of detection (LOD) and quantification (LOQ) for 2-amino pyridine were found to be 0.09 ppm and 0.3 ppm, respectively. The method demonstrated accuracy within the range of 89.1% to 106.6% for the analyte. The method's linearity was confirmed through a six-point calibration graph spanning 6 ppm to 75 ppm, corresponding to a concentration of 20 mg/ml of Tenoxicam.
Conclusion: Developed hyphenated LC-MS/MS method presented in this study offers a highly sensitive and accurate means for the determination of the genotoxic impurity 2-amino pyridine in Tenoxicam. With validated LOD and LOQ values, as well as demonstrated accuracy, this method proves to be a robust quality control tool suitable for the quantitation of 2-amino pyridine at very low concentrations in the pharmaceutical compound Tenoxicam.
AN OVERVIEW ON ORAL THIN FILMS–METHODOLOGY, CHARACTERIZATION AND CURRENT APPROACH
Authors: BADEKAR RUCHITA , BODKE VISHAL , TEKADE BHARAT W. , PHALAK SWAPNIL D.
Published: April 2024

The pharmaceutical sector is looking for new ways to deliver drugs, and one such way is through thin films. It has been said that thin films offer an alternative to traditional dosage forms. They offer rapid, local, or systemic effects and are a very flexible platform. Furthermore, patients with dysphagia, elderly, paediatrics, or bedridden patients, as well as those who have difficulty accessing water, can easily utilize these systems on their own. There are several ways to administer these drug delivery systems, including transdermally, ocularly, buccally, sublingually, and orally.
One of the most creative and patient-focused novel drug delivery systems is Orodispersible Thin Films (OTF). Numerous pharmaceutical companies and academic experts worldwide are currently investigating the potential of these films for delivering drugs derived from both synthetic and natural sources. The beauty of this special drug delivery method is that, as we can see from the subjects' consumption of conventional dosage forms (tablets, capsules), they don't require water to be consumed. Furthermore, these delivery methods do a great job of encouraging patient compliance in general, especially in the case of both older and pediatric patients.
This review shows a detailed review of oral thin film its applications and method of preparation; mainly focus of this research is thin film introduction to researchers and last 10 y of research on thin film with drugs and polymers used in research.
Планарная фотоника ближнего инфракрасного диапазона на основе сверхлегированного кремния: перспективы
Authors: Ковалев М.С. , Подлесных И.М. , Певчих К.Э. , Кудряшов С.И.
Published: April 2024

Появление кремниевой фотоники за последние два десятилетия создало
условия для того, чтобы кремний стал предпочтительной платформой для
фотонной интеграции. В этом обзоре мы предлагаем наш взгляд на растущую
область интегральной фотоники ближнего инфракрасного диапазона на кремнии
и перспективные технологии обеспечения этого роста. Представлен комплексный обзор
современного состояния таких ключевых фотонных устройств, как волноводы, источники света и детекторы.
Ultra-High Birefringence Property and Low Confinement Loss of Circular Photonic Crystal Fiber for Telecommunication Application
Authors: Rumpa Ramin Chapa
Published: April 2024

Abstract: A redesigned PCF structure with minimal confinement loss and high birefringence is proposed in this research paper. It employs a circular lattice arrangement with one ring of identical air holes. High birefringence and low confinement loss are two of the properties that have been numerically studied using the finite element method with circular perfectly matched layer boundary conditions. By adjusting the hole size and spacing, it is possible to achieve both properties simultaneously. At an excitation wavelength of 1550 nm, a numerically obtained modal birefringence of 2.3179×10-2 is observed. Simultaneously, by methodically evaluating the cladding rings, the center-to-center distance between the air holes, and the number of cladding rings with equal diameters, a minimal confinement loss (<10-1) may be achieved. Additionally, the suggested PCF verifies that it is feasible to acquire. Our extremely birefringent fiber can be controllably created thanks to the development of birefringence with structural modifications. The suggested structure has better optical characteristics, making it a potential contender for sensing and broadband dispersion correction.
Enhancing Image Realism Through Fine Grained Text to Image Synthesis
Authors: S Priyavarshini.
Published: April 2024

Abstract: We propose a more effective Deep Fusion Generative Adversarial Networks (DF- GAN) for synthesizing high-quality realistic images from text descriptions. The main challenges in this task are the entanglements between generators of different image scales, the reliance on extra networks for text-image semantic consistency, and the computational cost of cross-modal attention-based fusion. Ourproposed approach addresses these challenges as follow
Distributed Approach for Efficiently Extracting Common Patterns from Large Datasets
Authors: Senthil Dr. P.
Published: April 2024

Abstract: In recent years, advancements in database knowledge discovery have enabled it to find important and practical information with great force. Frequent pattern mining and association rule mining has been thoroughly investigated for a great range of real-world applications. Traditional mining algorithms use memory-resident, centralised data. The performance is not effective enough when applying these methods to remote databases because of the large amount of data, bandwidth limitation, and energy limitations, especially in this era of big data. Datamining in dispersed contexts has therefore become a significant field of study.
Implementation of Arduino Based System for Automatic Street Light Switching and Fault Detection
Authors: Bagal Prof. S. A.
Published: April 2024

Abstract: The imperative for deploying automated street lighting systems in India is underscored by the significant opportunity to enhance energy efficiency a pivotal goal for a country committed to optimizing energy use. Research indicates that transitioning to LED street lighting can lead to a 30% decrease in energy consumption, translating into a substantial electricity conservation of approximately 2,326 GWh. LED technology is renowned for its potential to reduce energy requirements by up to 80% in comparison to conventional lighting methods, offering a more sustainable alternative that significantly lowers electricity demand. Transitioning to energy-efficient lighting plays a vital role not only in diminishing energy use but also in contributing to environmental protection by reducing CO2 emissions. Furthermore, the incorporation of automated control mechanisms in street lighting systems, such as daylight sensors and solar panels, which adjust lighting based on sunlight exposure, further boosts energy efficiency.
Fortifying Software Security: Strategies, Implementation, and Challenges
Authors: Kosarkar Kajal
Published: April 2024

Abstract: In an increasingly interconnected world, where software applications underpin critical infrastructure, financial systems, and everyday interactions, ensuring robust security measures throughout the software development lifecycle has become paramount. This research paper conducts a comprehensive investigation into the multifaceted landscape of software security, examining key strategies, implementation techniques, and challenges encountered by developers. Drawing from an extensive review of literature, case studies, and emerging trends, this paper provides nuanced insights into effective approaches for mitigating security risks and fostering a culture of security awareness in software development endeavors
IOT Based Accident Alert System
Authors: Talekar Revati
Published: April 2024

Abstract: Transportation has great importance in our daily life and it’s development has made many of our chores much easy. IoT based accident alert system aims to provide real-time warnings to drivers as they approach hazardous areas using ESP32 Ultrasonic Sensors and RF Transmitter and Receiver has gained attention. When a vehicle or a car comes near the accident prone area, ESP32 alongwith Speaker and Audio amplifier whichis situated in a car produces a beep sound through which the driverin the car getsan alarmsound that thereis an accident prone area nearby.
Why there are so Many Programming Languages?
Authors: Paunikar Anuj
Published: April 2024

Abstract: This paper presents an overview on the existence of many programming languages. The exploration of privacy concerns in the 5G landscape necessitates an examination of the technological underpinnings that define this network's capabilities. From the increased reliance on edge computing to the proliferation of IoT devices, understanding the mechanics of 5G is crucial for comprehending the vulnerabilities that may compromise user privacy. Moreover, this paper aims to analyse the evolving regulatory landscape and policy frameworks surrounding data protection in the context of 5G, assessing their adequacy in safeguarding individual privacy rights.
3D CAD Model of Multifunctional Seat Used in Military Vehicle
Authors: Sahare Payal Lalchand
Published: April 2024

Abstract: The primary postural strain experienced by the human body on extended off-road journeys is caused by the vibrations transmitted to the undercarriage and vehicle structure through the seat, as well as by the seating posture impacting the spine. The absorption of shocks and vibrations that happen during travel, linked to changes in speed and manoeuvres like braking, is crucial to minimizing vibrations. The effectiveness of vibration reduction relies heavily on the overall suspension system of the vehicle, particularly the design of the seats.
Traffic Management using Real-time Density-Based Traffic Light Control System
Authors: Bakal Swapnali
Published: April 2024

Abstract: In modern times, cities commonly encounter a big challenge dealing with traffic issues. It's hard to find empty roads nowadays, and waiting at red lights takes forever. The traffic lights are set based on average traffic, but this causes issues at certain spots where traffic suddenly gets heavy. That's why we need a smart system that can handle traffic jams better by looking at how much traffic there is. This system would change the traffic lights in real-time, making things smoother and reducing wait times. In simple terms, we need a clever system to fix the traffic mess in our cities. One of the solution is to manage traffic on signal, traffic signal timing (TST) optimization is one of the fastest and most economical ways to curtail congestion at the intersections and improve traffic flow in the urban network. In this paper we are going to discuss some of the existing traffic light control systems, their drawbacks as well as our proposed system where we are trying to avoid the drawbacks of existing systems. The main objective of our project is to provide a smooth flow of traffic and to reduce the time duration for which one has to stand at the traffic signal. The cameras will monitor the density of vehicles standing at the signal using image processing.This camera takes pictures, and those pictures are analyzed to figure out the density of vehicles in particular lanes. The camera can also recognize sirens and, when it does, it changes the traffic light to green so that emergency vehicles like ambulances and fire trucks can pass through.
The Uniform Civil Code (UCC) in ASSAM: Debates, Impact and Possible steps
Authors: Nath Nabajit
Published: April 2024

Abstract: Article 44 of the Constitution says, "The State shall endeavour to secure for the citizens a uniform civil code throughout the territory of India." Assam is the third state, following Uttarakhand and Gujarat, all ruled by the Hindu nationalist BJP, to move toward a unified civil law for all religious groups, however the tribal communities, comprising 12.45 percent of the state’s population, will be exempted from the code. As per the government UCC will deal with four points — preventing underage marriage, banning polygamy, inheritance laws and registration of live-in relationships. It will not deal with traditional rituals or practices,” Even if the communities governed under the sixth schedule areas will be exempted, it will affect the other communities practising their customary rights. Based on the enumeration of the 2011 census, Assam has a population of 61.47 per cent Hindus, 34.22 per cent Muslims and 3.7 per cent Christians.
The Social Media Marketing: A Game Changer in the Modern Business-Case Study
Authors: N Arsath Ali
Published: April 2024

Abstract: Social media marketing has revolutionized the landscape of modern business, offering unprecedented opportunities for companies to engage with their audience, build brand awareness, and drive sales. This paper explores the transformative role of social media in reshaping traditional marketing strategies and its profound impact on businesses of all sizes. Through a comprehensive review of literature, this study examines the various techniques and tools utilized in social media marketing, including content creation, influencer partnerships, and targeted advertising. Additionally, it analyses the advantages and challenges associated with implementing social media marketing campaigns, such as reaching diverse demographics, managing online reputation, and measuring return on investment. Furthermore, the paper investigates the evolving trends and future prospects of social media marketing, including the rise of video content, augmented reality, and data-driven personalization. Overall, this research contributes to a deeper understanding of how social media has emerged as a pivotal force in driving business growth and innovation in the digital age.
A Study on the Influence of Feng Shui Factors on the Intention of Tenants to Renew Contracts in Multi-Auction History Commercial Facility: Focusing on the Seoul Commercial Facility
Authors:   Residential Environment Institute Of Korea, Jang Chunhui , Jang Heesoon
Published: April 2024

A Study on the Interpretation of Feng shui Factors in the Commercial Facility Location Analysis - Focused on the Multiple Auctions in Jung-gu, Seoul -Using the multiple auctions in Jung-gu, Seoul as a focal point, this study aims to analyze the interpretation of environmental factors in the location analysis of commercial facilities. The research focuses on the study of commercial facility locations, specifically in terms of their relationship with environmental factors.The research methodology includes the following steps: 1. Data Collection - Collect data related to commercial facility locations in Jung-gu, Seoul, particularly those obtained through multiple auctions. - Gather data on environmental factors such as geographic characteristics, natural environment (landscape, water, mountains, etc.), and geographical location. 2. Data Preprocessing - Preprocess the collected data to transform it into a suitable format for analysis - Cleanse the data and extract relevant variables for the study. 3. Environmental Factors Analysis: - Utilize Geographic Information Systems (GIS) to analyze the environmental factors related to commercial facility locations. - Conduct spatial analysis to identify patterns and relationships between commercial facilities and environmental factors. 4. Interpretation and Evaluation - Interpret the results of the analysis to gain insights into the interpretation of environmental factors in cmmercial facility location analysis - Evaluate the significance and impact of environmental factors on commercial facility locations in Jung-gu, Seoul. 5. Conclusion and Recommendations:Summarize the findings and draw conclusions based on the interpretation of environmental factors in commercial facility location analysis - Provide recommendations for future decision-making processes regarding commercial facility locations, taking into account the identified environmental factors. By conducting this study, we aim to contribute to the understanding and interpretation of environmental factors in the location analysis of commercial facilities, specifically focusing on the multiple auctions in Jung-gu, Seoul.
DEVELOPMENT OF INTERACTIVE LEARNING MEDIA BASED ON THE PROBLEM SOLVING METHOD USING PREZI FOR THE TOPIC OF ENVIRONMENTAL CHANGES
Authors: Hanim Nafisah , Zuraidah Zuraidah , Dewi Cut Ratna , Eriawati Eriawati , Ahadi Rizky , Muhsan Raihanul
Published: April 2024

The process of learning Biology is still dominated by teachers as the sole source of information, using less interactive teaching media such as chalkboards and textbooks. The use of interactive media is considered appropriate for fostering students' problem-solving abilities, especially in the topic of Environmental Changes. The development of interactive media is crucial. This study aims to develop an interactive learning media using Prezi based on the problem-solving method for the topic of Environmental Changes. The research utilizes the R&D (Research and Development) model following the Borg and Gall research design, with the following stages: potential and problem stage, data collection stage, product design stage, design validation stage, design revision stage, and product revision stage