bluuebunny/crossref_metadata_2025 huggingface dataset:
Features of employment in a singleindustry town on the example of Pavlovo, Nizhny Novgorod oblast
Authors: Kulikova Aleksandra , Mikhailova Veronika , Klemyatich Yulia , Teodorovich Mikhail
Published: June 2023

The article describes the main features of the labor market in Pavlovo, Nizhny Novgorod oblast, analyzes employment strategies of the population from different property groups. Due to its geographical location, socio-demographic structure, Pavlovo was chosen as an example of a typical small town in the European part of Russia. The article presents the results of sociological survey conducted in 2011 and 2021. The 2011 survey was carried out by the Institute of Socio-Economic Studies of Population of the FCTAS RAS (Moscow) and Lobachevsky State University of Nizhniy Novgorod (Nizhny Novgorod) with participation of the universities of Glasgow (Scotland) and Uppsala (Sweden). The 2021 survey — by the Center for the Study of Social Systems, the Department of Sociology of Project Activity and Pro-Competitive Regulation of the Lobachevsky State University of Nizhniy Novgorod., the universities of Glasgow (Scotland), Uppsala (Sweden) with the support of the Scientific Information Center, Nizhny Novgorod. As a result of the cluster analysis, four social groups were identified that differ from each other in socio-economic characteristics and strategies of behavior in the labor market. The relationship between the level of education and the position on the labor market is clearly visible. In the group of affluent households, there are more people who have higher education. Higher education and qualification level allow one to occupy higher-paying positions, diversify career strategies even in a single-industry city. While in low-income families, the share of those who are employed in the industrial sector, in particular, at the city-forming enterprise, is higher. Affluent households show the greatest economic activity, while combining additional ways of earning with the main specialty. It is important to note that the lower the family income level, the less often they use the opportunities for additional earnings. People of retirement age, while maintaining an average level of economic activity and sufficient labor potential (education, skill level), are quite severely limited in employment opportunities. Factors reducing the material well-being of family are the presence of minor children, the position of a single parent, the status of a pensioner. Those living alone are also often low-income, especially women.
“It Won't Be So Expensive”: Approaches to the Organization of Scientific Work in the 1930s.
Authors: Dolgova Evgenia
Published: June 2023

The article examines the change in approaches to stimulating and organizing scientific work during the years of Soviet industrialization. On the example the Central Commission for Improving the Life of Scientists and the Commission for Assistance to Scientists (since 1931) the author characterizes the transition from socio-economic support to stimulate collectivism and high rates of scientific output, especially actualized under Taylor's influence and during the years of the Stakhanov movement. The author concludes these changes affected the industrial culture of that time because of the ideas of the individual scientific work changed of the division of labor and providing production capacities of scientific collectives. Special attention is paid to the projects of organizing collective research – “auxiliary workshops” at scientific organizations. The research is based on the documents of the unpublished analytical report “On accelerating the pace of scientific work” and the materials of its discussion at the meeting of the Commission for Assistance to Scientists, identified in the State Archive of the Russian Federation.
Personnel Problems in Domestic Science
Authors: Klistorin Vladimir
Published: June 2023

The paper discusses the problems of scientific activity effectiveness, especially the quality of scientific personnel training, formation and maintenance of creative climate in research teams, and certification of scientific workers. The majority of the works devoted to the problems of domestic science development discuss the problems of low demand for the results of research and publication activity at the international level, aging of research teams and the problem of youth flow-in into science, material and financial support of scientific research, the structure of research and its compliance with the most demanded areas of knowledge and much more. Much less attention in the scientific literature is paid to the problem of the use of human capital in science, and usually the conclusions are reduced to the problem of insufficient funding of fundamental research. The article discusses the process of training of highly qualified researchers, argues that a special role in this is played by on-the-job training, justifies the need to create conditions for the flow of scientific personnel and extensive informal cooperation of scientists. It is shown from the standpoint of the theory of human capital and special interest groups that such mechanisms to a certain extent ensure the effectiveness of scientific research. Some decisions of the Ministry of Education and Science of the Russian Federation regarding the stimulation of scientific research productivity are considered. It is shown that the approaches of the Ministry in this area are reduced to the orientation of scientists to achieve formal quantitative indicators, which ultimately leads to a decrease in the quality of R&D. Moreover, the focus on quantitative indicators leads to individualization of research work, reduction of incentives for creative communication and scientific criticism. Another problem is the formation of scientific nomenclature and the growing isolation of domestic science from the world. The tightening of criteria and the increasing complexity of scientific certification procedures on the basis of the same quantitative approaches and growing centralization in decision-making lead rather to the opposite result – the quality of researchers and the effectiveness of their work are declining. The general conclusion is that the domestic science needs actual decentralization both in the choice of research topics and in the personnel policy.
HUBUNGAN ANTARA DUKUNGAN MANAJEMEN, PENGETAHUAN DAN SIKAP TERHADAP KEPATUHAN KARYAWAN PADA PROTOKOL PENCEGAHAN COVID 19 DI PT. ASURANSI SINARMAS JAKARTA
Authors: Sangadji Namira Wadjir , Aningsih Aningsih
Published: June 2023

Kenaikan angka kasus COVID 19 dapat disebabkan karena faktor ketidak kapatuhan dalam menerapkan protokol kesehatan selama masa pandemi khususnya oleh para karyawan. Aktivitas bekerja di kantoran menyebabkan tingginya mobilitas dan interaksi sesama karyawan. Studi pendahuluan yang dilakukan di PT. Asuransi Sinarmas Jakarta ditemukan 68% karyawan belum patuh dalam melakukan pencegahan COVID 19 di tempat kerja. Tujuan dari penelitian ini adalah mengetahui variabel –variabel yang berhubungan dengan kepatuhan karyawan terhadap protokol kesehatan di PT. Asuransi Sinarmas Jakarta. Metode yang dipakai yaitu metode kuantitatif dengan desain cross sectional. Penelitian ini dilaksanakan pada bulan September - Desember 2020. Pengumpulan data primer dilakukan melalui google form dan disebarkan secara daring. Populasi pada penelitian ini adalah semua karyawan di PT. Asuransi Sinarmas Jakarta. Sampel dalam penelitian ini berjumlah 98 karyawan dengan metode pengambilan sampel secara total sampling. Analisis data dilakukan secara univariat dengan persentase dan bivariat dengan uji Chi Square. Hasil menunjukan 30,6% karyawan tidak patuh pada tidakan pencegahan COVID 19 di tempat kerja. Variabel pengetahuan tentang COVID 19, sikap, dan dukungan manajemen perusahaan berpengaruh secara signifikan terhadap kepatuhan karyawan dalam protokol pencegahan COVID-19 di tempat kerja.
GAMBARAN AKREDITASI PUSKESMAS INDONESIA BERDASARKAN DATA SEKUNDER DARI RISET FASILITAS KESEHATAN 2019
Authors: Mawarni Dian , Sabran Sabran , Puspitasari Sendhi Tristanti , Wardani Iing Merillarossa Kharisma
Published: June 2023

Kebijakan akreditasi fasilitas pelayanan kesehatan tingkat pertama berperan memastikan pemerataan mutu pelayanan kesehatan masyarakat. Sejak 2015, belum ada kajian mengeksplorasi capaian akreditasi Puskesmas seluruh provinsi Indonesia. Penelitian bertujuan mengetahui gambaran akreditasi Puskesmas Indonesia dan mengidentifikasi determinan dari karakteristik Puskesmas. Penelitian ini menggunakan data sekunder dari Riset Fasilitas Kesehatan 2019. Sebanyak 8.543 Puskesmas memenuhi kriteria untuk dianalisis. Uji Chi-Square untuk menilai hubungan karakteristik Puskesmas dengan status akreditasi. Penelitian ini menunjukkan sebagian besar Puskesmas memiliki layanan rawat inap (56,72%), terletak di desa (48,58%), telah terakreditasi (79,19%), memiliki predikat madya akreditasi (56,07%), dan non BLUD (68,14%). Penelitian ini menjelaskan adanya hubungan kemampuan pelayanan, kategori wilayah, pola pengelolaan keuangan dengan status akreditasi Puskesmas. Penelitian ini menyimpulkan kebijakan akreditasi fasilitas kesehatan tingkat pertama belum terlaksana secara menyeluruh di Puskesmas Indonesia. Oleh karena itu perlu optimalisasi peran Dinas Kesehatan Kabupaten/Kota dalam memberikan pendampingan akreditasi terutama Puskesmas dengan karakteristik memiliki layanan rawat jalan, daerah terpencil, dan non BLUD.
WANITA NELAYAN: SANITASI DAN USAHA KESEHATAN KELUARGA
Authors: Moelyaningrum Anita Dewi , Khoiron Khoiron , Ma`rufi Isa , Nurika Globila , Kusnadi Kusnadi
Published: June 2023

Indonesia adalah negara maritim dengan panjang garis pantai sepanjang 108.000 km. Profesi nelayan menjadi pilihan masyarakat yang tinggal dikawasan pesisir. Wanita nelayan adalah istri nelayan yang berperan dalam keberlangsungan rumah tangga nelayan. Tujuan dalam penelitian ini adalah menggambarkan peran wanita nelayan dalam upaya sanitasi serta kesehatan dan keselamatan keluarga. Metode penelitian adalah observasional dengan pendekatan cross-sectional. Data dianalisa secara kualitatif dan kuantitatif. Responden penelitian ini adalah wanita nelayan dengan kepala rumah tangga nelayan yang masih aktif melaut sebanyak 60 orang responden dan berdomisili di Desa Jangkar, Kabupaten Situbondo, Jawa Timur. Hasil penelitian menunjukkan bahwa rerata usia responen adalah 35 tahun dengan pendidikan sebagian besar lulus Sekolah Menengah Pertama (SMP), memiliki aktivitas ekonomi untuk membantu keuangan keluarga. Responden memiliki harapan yang tinggi untuk anak anak mereka untuk dapat bersekolah hingga perguruan tinggi, lebih memilih pendidikan berbasis agama, dan ingin memiliki 3 orang anak pada setiap keluarga. Pelayanan kesehatan yang dipilih keluarga adalah puskesmas, serta melakukan pemantauan kelengkapan imunisasi anak. Responden berperan dalam upaya keselamatan kepala keluarga saat melaut dengan mengingatkan penggunaan Alat Pelindung Diri, waktu istirahat, mempersiapkan kelengkapan melaut, menyediakan menu yang bergizi maupun suplemen supaya tetap bugar saat melaut. Kondisi sanitasi dan hygiene masih kurang, karena masih membakar sampah, dan memiliki aluran air limbah tidak sanitair. Perlu peningkatan pendidikan supaya mampu mendukung diversitas usaha yang lebih menguntungkan secara ekonomi, serta peningkatan sarana sanitasi, serta perlu pelatihan cara mengolah sampah rumah tangga berbasis peningkatan ekonomi untuk menurunkan beban pencemaran lingkungan pesisir sekaligus dapat membantu peningkatan pendapatan.
Assessment of engine valve materials
Authors: Tomaszewski Szymon , Grygier Dominika , Dziubek Mateusz
Published: June 2023

This paper presents an analysis of six sets of engine valves, each set consisting of one exhaust valve and one intake valve. Each pair of valves was used in an engine with different displacement and mileage. The valves were subjected to microscopic analysis, hardness measurement and chemical composition analysis using a glow discharge spectrometer and energy dispersive spectroscopy (EDS). The design and materials of the valves showed that both the intake and exhaust valves in their present form would be a strength of the engine.
Os agentes múltiplos na coluna de artes plásticas do suplemento literário do Minas Gerais: 1966-1973
Authors:   Universidade Federal de Minas Gerais, Matos Lucas Moraes
Published: June 2023

O que define a crítica de arte? Onde persiste o desinteresse ou pouco conhecimento relacionado às artes visuais, como no caso da cultura brasileira, a crítica especializada pode se apresentar como uma excentricidade. Apesar do estranhamento, esta nem sempre foi a realidade apresentada. Pelo levantamento, realizado pelo grupo de pesquisa Memória das Artes Visuais em Belo Horizonte (MAV-BH), para esta pesquisa, foi possível notar que o circuito artístico em Belo Horizonte foi movimentado, pela crítica de arte principalmente durante as décadas de 60 e 70, através de uma coluna do Suplemento Literário, caderno (ainda ativo) anexo ao jornal oficial do Estado, o Minas Gerais, o qual contou com pelo menos 491 textos críticos. Dada a atual situação das artes visuais, esse cenário se mostra um tanto provocativo. Nesse sentido, compreendemos a crítica de arte como parte de um sistema que envolve artistas, obras de arte, museus, coleções, galerias e todo o conjunto de elementos capazes de definir o campo artístico como autônomo.
Immunohematologic Biomarkers in COVID-19: Insights into Pathogenesis, Prognosis, and Prevention
Authors: Sweet David , Freeman Michael , Zidar David
Published: June 2023

Coronavirus disease 2019 (COVID-19) has had profound effects on the health of individuals and on healthcare systems worldwide. While healthcare workers on the frontlines have fought to quell multiple waves of infection, the efforts of the larger research community have changed the arch of this pandemic as well. This review will focus on biomarker discovery and other efforts to identify features that predict outcomes, and in so doing, identify possible effector and passenger mechanisms of adverse outcomes. Identifying measurable soluble factors, cell-types, and clinical parameters that predict a patient’s disease course will have a legacy for the study of immunologic responses, especially stimuli, which induce an overactive, yet ineffectual immune system. As prognostic biomarkers were identified, some have served to represent pathways of therapeutic interest in clinical trials. The pandemic conditions have created urgency for accelerated target identification and validation. Collectively, these COVID-19 studies of biomarkers, disease outcomes, and therapeutic efficacy have revealed that immunologic systems and responses to stimuli are more heterogeneous than previously assumed. Understanding the genetic and acquired features that mediate divergent immunologic outcomes in response to this global exposure is ongoing and will ultimately improve our preparedness for future pandemics, as well as impact preventive approaches to other immunologic diseases.
Therapeutic Effect of Enzymatic Hydrolyzed Cervi Cornu Collagen Np-2007 and Application in Osteoarthritis
Authors: Kim Ha-Rim , Lee Seung-Hyeon , Noh Eun-Mi , Choi Bongsuk , Seo Hyangyim , Jang Hansu , Kim Seon-Young , Park Mi Hee
Published: June 2023

Cervi cornu has been extensively used in traditional medicine as an antioxidant and for the treatment of various disorders, including osteoporosis. However, since it is not easy to separate the active ingredient, absorption is not performed well. In this study, we extracted the low molecular weight (843Da) collagen NP-2007 from cervi cornu by enzyme hydrolyzation, and evaluated the therapeutic effect in a monosodium iodoacetate (MIA)-induced rat osteoarthritis model, and identified their molecular mechanisms. NP-2007 was orally administered at 50, 100, and 200 mg/kg for 21 d. Efficacy was evaluated based on serum parameters, inflammatory mediators, and mor-phological and histopathological analyses of knee joints. Production of matrix metalloproteinases, including MMP-2, MMP-3, and MMP-9, in the serum was higher in MIA-treated rats; however, these levels decreased after NP-2007 treatment. Serum levels of tumor necrosis factor-α, interleukin (IL)-1β, IL-6, and prostaglandin E2 were lower in the NP-2007 group than in the MIA group. Furthermore, the administration of NP-2007 resulted in effective preservation of both the synovial membrane and knee cartilage, and significantly decreased the transformation of fibrous tissue. This study indicates that NP-2007 can prevent and alleviate symptoms of osteoarthritis and have applications as a novel arthritis treatment.
Essential Thrombocythemia and Ischemic Stroke: A Case Series of Five JAK2-Positive Patients
Authors: Kim Byong-Kyu , Eah Kyung Yoon , Park Jin-Mo
Published: June 2023

Objectives: Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm characterized by elevated platelet counts and an increased risk of thrombotic events, including ischemic strokes. Methods: We conducted a retrospective analysis of data from consecutive ischemic stroke patients with ET between March 2014 and February 2023. Results: This case series describes the clinical presentation, radiological features, and management of five patients with ET-associated ischemic strokes, all harboring the JAK2 mutation. The diverse radiological findings suggest that both large and small vessel diseases may be influenced by the prothrombotic state induced by ET. A significant elevation in platelet count was observed to correlate with the emergence of new acute infarctions in some cases. Conclusions: The study highlights combined use of antiplatelet and cytoreductive therapy in preventing secondary stroke events in patients with ET and JAK2 mutations. The heterogeneity of stroke patterns in this population necessitates a comprehensive understanding of the underlying pathophysiological mechanisms and tailored therapeutic approaches.
Mouse Models for HTLV-1 Infection and Adult T-cell Leukemia
Authors: Nakajima Shinsuke , Okuma Kazu
Published: June 2023

Adult T-cell leukemia (ATL) is an aggressive hematologic disease caused by human T-cell leukemia virus type 1 (HTLV-1) infection. Various animal models of HTLV-1 infection/ATL have been established to elucidate the pathogenesis of ATL and develop appropriate treatments. For analyses employing murine models, transgenic and immunodeficient mice are used because of the low infectivity of HTLV-1 in mice. HTLV-1 Tax and HBZ transgenic mice spontaneously develop tumors, and roles for both Tax and HBZ in cell transformation and tumor growth have been established. Severely immunodeficient mice were able to engraft ATL cell lines and have been used in preclinical studies of candidate molecules for the treatment of ATL. HTLV-1-infected humanized mice with an established human immune system are a suitable model to characterize cells in the early stages of HTLV-1 infection. This review outlines the characteristics of mouse models of HTLV-1 infection/ATL and describes progress made in elucidating the pathogenesis of ATL and developing related therapies using these mice.
Evidence for Microchimerism in Baboon Recipients of Pig Hearts
Authors: Jhelum Hina , Bender Martin , Reichart Bruno , Mokelke Maren , Radan Julia , Neumann Elisabeth , Krabben Ludwig , Abicht Jan-Michael , Kaufer Benedikt , Längin Matthias , Denner Joachim
Published: June 2023

Xenotransplantation is, like allotransplantation, usually associated with microchimerism, e.g., the presence of cells from the donor in the recipient. Microchimerism was reported in first xenotransplantation trials in humans as well as in most preclinical trials in non-human primates (for review see Denner, Viruses 2023, 15, 190). When using pigs as xenotransplantation donors, their cells contain porcine endogenous retroviruses (PERVs) in their genome. That makes it difficult to discriminate between microchimerism and PERV infection of the recipient. Here, we demonstrate which virological methods should be used to identify microchimerism, first of all screening for porcine cellular genes. Using porcine short interspersed nuclear sequences (SINES), which have hundred thousands of copies in the pig genome significantly increased the sensitivity of the screening for pig cells. Second, absence of PERV RNA demonstrated an absence of viral genomic RNA or expression as mRNA. Finally, absence of antibodies against PERV proteins conclusively demonstrated an absence of a PERV infection. When applying these methods for analyzing baboons after pig heart transplantation, microchimerism could be demonstrated in all animals. These methods can be used in future clinical trials.
Modeling of the Spatial Distribution of Forest Carbon Storage in a Tropical/Subtropical Island With Multiple Ecozones
Authors: Chang Ting-Wei , Chen Guan-Fu , Chang Ken-Hui
Published: June 2023

Visual data on the geographic distribution of carbon storage helps policy maker to formulate countermeasures on global warming. However, Taiwan, as an island showing diversity in climate and topography, had lacked valid visual data in distribution of forest carbon storage between the last to forest surveys (1993-2015). This study established a model to achieve an estimation that capable to demonstrate the distribution of forest carbon storage. This model uses land use, stand morphology, carbon conversion coefficient databases accordingly for 51 types of major forest in Taiwan. An estimation on 2006 was conducted and shows an overall carbon storage of 165.65 Mt C, with forest carbon storage per unit area of 71.56 t C ha–1, where natural forests and plantations respectively contributed of 114.15 Mt C (68.9%) and 51.50 Mt C (31.1%). By assuming no change in land use type, the carbon sequestration from 2006 to 2007 by the 51 forest types was estimated to be 5.21 Mt C yr–1 using historical tree growth and mortality rates. The result reflects the reality of the land use status and event of coverage shifting with time by combining to the two forest surveys in Taiwan.
The Transition to a Renewable Energy Electric Grid in the Caribbean Island Nation of Antigua and Barbuda
Authors: Hoody Patrick , Chiasson Andrew , Brecha Robert J.
Published: June 2023

The present study describes the development and application of a computer model of the national electricity system for the Caribbean dual-island nation of Antigua and Barbuda to investigate the cost-optimal mix of solar photovoltaics (PV), wind, and in the most novel contribution, concentrating solar power (CSP). These technologies, together with battery and hydrogen energy storage, can enable the aim of achieving 100% renewable electricity and zero carbon emissions. The motivation for this study was that while most nations in the Caribbean rely largely on diesel fuel or heavy fuel oil for grid electricity generation, many countries have renewable resources beyond wind and solar energy. Antigua and Barbuda generates 93% of its electricity from diesel-fueled generators and has set targets of becoming a net-zero nation by 2040 and having 86% renewable energy generation in the electricity sector by 2030, but the nation has no hydroelectric or geothermal resources. The modeled, optimal mix of renewable energy technologies presented here was found for Antigua and Barbuda by assessing the levelized cost of electricity (LCOE) for systems comprising various combinations of energy technologies and storage. Other factors were also considered, such as land use and job creation. It was found that 100% renewable electricity systems are viable and significantly less costly than current power systems, and that there is no single defined pathway towards a 100% renewable energy grid, but several options are available.
Unleashing Black Sea Cucumber's Potential: Identifying Anti-Cancer Compounds Through In Silico Drug Discovery
Authors: Romdendine Muhammad Fahrury , Kusuma Wisnu Ananta , Annisa Annisa , Nurilmala Mala , Fitriani Rizka
Published: June 2023

Despite being an abundant marine organism in Indonesia, black sea cucumber is still underutilised due to its slightly bitter taste. Previous studies have hinted at the potential of black sea cucumber as an anti-cancer agent. However, specific identification of bioactive compounds that can interact with cancer proteins is still lacking. In the same place, cancer ranks third as Indonesia's leading cause of death. Therefore, this study aims to identify potential anti-cancer compounds from black sea cucumbers using a comprehensive in silico drug discovery approach. This research uses machine learning, molecular docking, and ADMET analysis to identify bioactive compounds that specifically interact with cancer proteins. A combination of the Cascade Deep Forest algorithm and ECFP-AAIndex1 feature combination proved to be the most effective in predicting these interactions. Through molecular docking validation, four bioactive compounds with strong binding affinity were identified: Afimoxifene, Danazol, Taxifolin, and Terfenadine. ADMET analysis highlighted Taxifolin as the most promising candidate, as it passed most ADMET parameters. Further wet laboratory studies are required to confirm the effects and potential of these compounds as anti-cancer agents. This study builds a foundation for future investigations into alternative cancer treatments using abundant natural resources.
The Impact of COVID 19 on Medical Staff Mental and Professional Wellbeing: A Longitudinal Study. Are Doctors Really Stronger than Nursing Staff?
Authors: Mendlovic Sefi , Haklay Idan , Eliot Roxane , Lahad Mooli
Published: June 2023

This study examines the psychological repercussions of the COVID-19 pandemic on a medical team in an Israeli general hospital. The research explores the professional quality of life, burnout symptoms, secondary traumatic stress, and mindfulness among team members across three distinct phases of the pandemic. Analysis was conducted for different subgroups based on job roles and seniority, allowing for an evaluation of the phase-specific effects on the ProQOL (Professional Quality of Life) and mindfulness. Results align with established crisis trajectories, encompassing honeymoon/heroic phases, inventory, disillusionment, and recovery. The findings demonstrate a negative correlation between compassion satisfaction and burnout, as well as between mindfulness and burnout/secondary traumatic stress. Remarkably, male doctors exhibit a more pronounced negative impact on mindfulness compared to their female counterparts, primarily comprising healthcare workers. Temporal analysis reveals significant differences in compassion satisfaction and mindfulness, with baseline measurements being notably higher. Furthermore, the study sheds light on the vulnerability of male doctors, emphasizing the crucial role of hospital management in conveying the message and implementing effective measures to support professional quality of life. These findings underscore the necessity of prioritizing the well-being of medical professionals, particularly male doctors who face unique challenges in seeking assistance.
Model and Simulation of Benefit Distribution of Collaborative Cooperation in the Supply Chain of General Contracting Projects
Authors: Wang Dan , Gao Wenwen
Published: June 2023

To solve the benefit allocation problem between the subjects of the supply chain of general contracting projects. The Cobb-Douglas function is applied to establish the benefit distribution model when the two cooperate in the supply chain system, analyze the optimal benefit situation of one-time cooperation between the two parties under two modes of egoistic decision and collectivistic decision as well as the benefit distribution problem of multiple cooperation, and conduct numerical simulation to calculate the functional relationship between each decision variable and the contribution degree of the general contractor under different effort cost coefficients. The results show that：In the case of one-time cooperation between general contractors and subcontractors, regardless of the decision mode, the degree of effort of both parties is positively related to their own contributions and negatively related to each other's contributions; the overall benefit of the supply chain system is positively proportional to the degree of contribution of the general contractor and inversely proportional to the share of benefit distribution of the subcontractor; in multiple cooperation, the equilibrium result of both parties achieving Pareto optimality at each stage is that both parties choose to cooperate.
Hyperautomation in Government Digital Transformation
Authors: Pinheiro Álvaro , Guimarães Romero
Published: June 2023

Este artigo apresenta o processo de implementação da Hiperautomação no setor público brasileiro, especialmente no âmbito da Procuradoria Geral do Estado de Pernambuco. Devido à atual economia competitiva, a demanda por soluções inteligentes e confiáveis está aumentando. Para atender a essa necessidade, tecnologias inovadoras que abordem a complexidade inerente à transformação digital são desejáveis. Assim, as organizações públicas têm buscado aplicar a automação de processos para atender às necessidades dos cidadãos por um serviço mais eficiente e eficaz. No entanto, podemos observar que a automação pura e direta é apenas parte do processo de transformação. Algumas das razões que explicam a necessidade de ir além da automação de processos e alcançar a hiperautomação é a abundância de dados de várias fontes e tipos. Tudo deve estar dentro dos padrões legais, ressaltando que toda tecnologia deve estar alinhada com transparência e auditabilidade para ser incorporada com segurança. Para a experimentação, foi utilizado o método de pesquisa-ação com a aplicação da Hiperautomação, visando aumentar a arrecadação e a economia do Estado na Procuradoria Geral do Estado de Pernambuco.
Dental implants and bleeding disorders: review and clinical indications
Authors: Bacci Christian , Schiazzano Claudia , Zanon Ezio , Stellini Edoardo , Sbricoli Luca
Published: June 2023

Background: Bleeding disorders can be divided into three categories: congenital coagulation disorders (CCDs), antiplatelet induced bleeding disorders (APBDs) and anticoagulant induced bleeding disorders (ACBDs). Implant placement can be challenging in this kind of patients. The aim of this study is to provide evidence on implant surgery in patient with bleeding disorders and to generate some practical recommendations for clinicians. Material & Methods: Pubmed/MEDLINE, Scopus, Web of Science and Cochrane Library databases were screened. The latest search was performed in July 2022. Case Reports, Case Series, Cohort Studies, Cross-Sectional Studies, Case Control Studies, Reviews, Consensus Reports, Surveys and Animal Studies were included in the analysis. Results: Seventeen articles on CCDs were found, fourteen on APBDs, twenty-six on ACBDs. Most of these articles were case report or case series. Patients with CCDs can be treated after the infusion of the missing coagulation factor. Patients with APBDs can be treated without withdrawing the therapy. Patients with ACBDs should be treated depending on the anti-coagulative medication. Conclusion: Despite the low level of evidence, dental implants can be safely placed in patients with bleeding disorders. However, careful preoperative evaluation and the adoption of local and post-operative bleeding control measures are mandatory.
MPI+OpenMP methods for implementing the conjugate gradient method with the IC(0) preconditioner based on the use of grid node reordering
Authors: Milyukova Olga Yurievna
Published: June 2023

The paper considers two ways of using MPI and MPI+OpenMP technologies for constructing and inverting the preconditioner of an incomplete triangular Cholesky decomposition without filling IC(0) for solving systems of linear algebraic equations with an arbitrary symmetric positive definite matrix. They differ in the way in which the preconditioning matrix IC(0) is computed. Methods of using MPI and MPI+OpenMP technologies are based on the use of grid node orderings consistent with the division of the calculation area. The use of OpenMP technology in the construction and inversion of the preconditioner is carried out for most rows of the matrix. Comparative timing results for the MPI+OpenMP and MPI implementations of the proposed preconditioning used with the conjugate gradient method for a model problems and the sparse matrix collections SuiteSparse as well as comparing the time of solving these problems using two methods of using MPI and MPI + OpenMP technology are presented.
Eating Habits and Nutritional Adequacy of the Transgender (Hijra) Community Residing In and Around Mumbai
Authors: Joshi Sheetal , Yardi Veena
Published: June 2023

For centuries, the Hijra enjoyed a special respect in the Hindu and Islamic cultures however, over the time, stigmatization took its toll and today the community is pushed to live on extreme societal margin. The present study was undertaken to assess the nutritional status of 304 transgender (Male to Female) residing in and around Mumbai using a mixed method approach. Participants were selected using a purposive sampling technique with the help of three Community Based Organisations (CBOs) working in close association with transgender. Data related to their nutritional status was collected before the pandemic using Food Frequency Questionnaire, 24-hr Recall and anthropometric measurements. Data related to impact of COVID-19 pandemic on food habits of transgender was collected from eight key informants working with CBOs using in-depth telephonic interviews. Results indicated that consumption of calorie dense junk foods was high and that of immunity building micronutrient dense foods such as fruits, vegetables and milk was notably low. Mean intake of macronutrients was adequate but that of micronutrients was lower for the majority. BMI assessment showed that 13 and 49% were underweight and overweight /obese respectively. COVID-19 pandemic further worsened nutritional status. The findings of the study may serve as basis for formulation of effective nutrition intervention programmes for transgender community.
Triple Burden of Malnutrition: A Reminder to Reform
Authors: Sai Gayathri H. , Thirumani Devi A.
Published: June 2023

The Triple Burden of Malnutrition is one of the most alarming issues of the current world. The current study focuses on the occurrence of triple burden of malnutrition in young adult women and impact of personalized nutrition education on the nutritional status of young adult women in the age group of 18- 21 years. The subjects were provided with questionnaire to collect the demographic and dietary data and also to screen the subjects for nutritional deficiencies. The study was conducted on 200 students and were assessed their nutritional status using ABCD technique such as Anthropometric Measurements (height, weight, BMI, waist and hip circumference, waist and hip ratio), Biochemical Estimation, Clinical Examination and Dietary pattern (24 hour recall method, Food frequency table).The subjects were categorised into under nutrition, over nutrition and micronutrient deficiencies. They were provided with personalised nutrition education on the basis of their nutritional status and requirements.
Exploring Therapeutic Potential of Ginger: Preclinical and Clinical Review
Authors: Otari Anuradha D. , Patil Rupali A.
Published: June 2023

Major attention is being paid to ginger's potential clinical uses in the hopes of achieving significant therapeutic effects. This thorough review seeks to offer a thorough explanation of the clinical effects of ginger in many documented areas. Systematic reviews, meta-analyses, and randomised controlled trials on the effects of ginger were mentioned. The study design, population characteristics, and primary outcomes of the review and research papers were all thoroughly examined. Along with anti-inflammatory effects, it has been shown to help cancer types, digestive issues, anti-diabetic metabolic syndromes, and motion sickness and vomiting during pregnancy. Calcium channel blockers as well as antibiotics have shown synergistic effect with ginger in preventing platelet aggregation. Ginger has the capacity to fend off illness.
Characterization of Bio-Degradable Plant Based Film to Enhance the Shelf Life of Perishable Food
Authors: Kumari Preeti , Kumar Avinash , Chakraborty Manali , Budhwar Savita , Kumar Suneel
Published: June 2023

The present study discloses the role of developed fenugreek-based biofilms to enhance shelf life of perishable foods. The biofilms were prepared in different variations [fenugreek: agar] i.e. V0 (100:0), V1 (90:10), V2 (80:20), V3 (70:30) and are characterized on the basis of transparency and thickness along with other functional properties. Obtained data indicated better transparency for V1 (2.50) in comparison with V2 and V3.The variations were able to retain nutritional contents viz., antioxidant property, ascorbic acid, phenolic content and percentage weight loss in coated sample with negligible nutrient loss compared to that of uncoated sample. Further, the samples have been irradiated using gamma source, to observe the effect of combined treatments (biofilm and gamma radiation). Recorded observation depicts enhanced shelf life of coated – irradiated sample (V1- Ir) for 19 days. The current study discloses the strategic approach of plant-based biofilm and radiation in improving shelf life of perishable foods.
ANALISIS PENGARUH PROFIL SUDUH TERHADAP DAYA TURBIN VORTEX
Authors: Marfizal Marfizal , Sufiyanto Sufiyanto , Wardianto Dedi
Published: June 2023

Abstrak

Turbin vortex adalah turbin yang beroperasi dengan memanfaatkan aliran vortex sebagai penggerak sudu-sudu turbin yang kemudian poros turbin dihubungkan ke generator untuk mengkonversi energi mekanis poros kedalam bentuk energi listrik. Pada penelitian ini akan dilakukan pengujian terhadap turbin vortex dengan head 1 m, debit aliran 0,12 m3/s. dalam proses pengujian akan di gunakan 3 jenis sudu, yaitu sudu lurus, sudu lengkung dan sudu lengkung bersirip. Setelah dilakukan pengujian dapat disimpulkan bahwa  daya tertinggi terdapat pada sudu lengkung  sebesar 959,08 watt dan  berikutnya sudu lengkung bersirip   714.38 watt, sedang kan daya terendah terdapat pada jenis sudu lurus 582.48 Watt. Untuk putaran yang dihasilkan dapat terlihat pada grafik dibawah,   Putaran  tertinggi terdapat pada sudu lengkung   bersirip sebesar 540,00 rpm dan  berikutnya sudu lengkung    517.67 rpm, sedang kan putran terendah terdapat pada jenis sudu lurus 510.67 rpm. Untuk effisiensi masing masin sudu terhat bahwa sudu lengkung masih tertinggi dan diikuti sudu jenis lengkung bersirip, terendah sudu lurus dengan effisiensi masin masin 98 %, 73 % dan 59%.
PENGARUH PENAMBAHAN ABU ARANG TEMPURUNG KELAPA TERHADAP KUAT TEKAN PAVING BLOCK
Authors: A Arman , Mulyati Mulyati , Wardi Syafri , Roza Angelalia , Sonia Putra Didi
Published: June 2023

Paving Block adalah bahan bangunan yang dibuat dari campuran semen, pasir dan air. Paving Block banyak digunakan dalam bidang konstruksi, seperti tortoar, jalan raya, lahan parkir, taman dan lainnya. Kemudahan dalam pemasangan, perawatan yang murah serta memenuhi aspek keindahan mengakibatkan paving block lebih banyak disukai. Seiring dengan banyaknya pembangunan seperti rumah, taman, jalan di tengah-tengah masyarakat saat ini, sehingga mengakibatkan kebutuhan paving block semakin meningkat. Karena proses pengerasannya membutuhkan waktu yang cukup lama, maka dari itu untuk mempercepat pengerasan, penelitian ini menanbahkan bahan Abu Tempurung Kelapa. Dalam penelitian ini menggunakan perbandingan 1 Pc: 3 Ps dan ditambahan Abu Tempurung kelapa dengan Variasi 0 %, 2,5 %, 5 %, dan 7,5 % dari berat semen. Nilai kuat tekan paving block rencana rata-rata Minimal 12,5 MPa dan Maksimal 15 MPa untuk mutu C yang dipergunakan untuk Pejalan kaki dan penggunaan lain, dengan benda uji persegi panjang dengan ukuran 20 cm x 10 cm x 6 cm sebanyak 24 buah dengan umur pengujian 28 hari untuk pengujian kuat tekan dan penyerapan air. Berdasarkan hasil pengujian didapatkan nilai kuat tekan paving block normal sebesar 13 Mpa, penambahan Abu Tempurung Kelapa 2,5 % didapatkan sebesar 13,5 MPa, Abu Tempurung 5 % didapatkan sebesar 14,5 Mpa, Penambahan Abu tempurung 7,5 % didapatkan sebesar 12,83 Mpa. Berdasarkan hasil pengujian didapatkan nilai penyerapan air Paving Block normal sebesar 7,8 %, Abu Tempurung 2,5 % sebesar 7,22 %, Penambahan Abu Tempurung 5 % sebesar 6,3 %, Abu Tempurung 7,5 % sebesar 4,89%. Dengan demikian dapat dinyatakan bahwa pengaruh Abu Tempurung Kelapa dapat meningkat kuat tekan dam menurunkan penyerapan air. Kuat tekan tertinggi dan penyerapan air terendah di peroleh pada penambahan 5% untuk kuat tekan dan penyerapan Air terendah diperoleh penambahan 4,89 %.
PENGARUH PERLAKUAN TANAM TERHADAP HASIL PANEN TANAMAN PADI
Authors: Putri Anindita Rahmalia , Wahyudi Bayu
Published: June 2023

Ketahanan pangan menjadi isu yang diperhatikan oleh masyarakat dunia beberapa tahun ini. Ketersediaan pangan sangat bergantung pada kestabilan pertanian. Namun pertanian adalah salah satu sektor yang sensitif terhadap iklim. Meskipun perbaikan terus-menerus dalam teknologi dan varietas tanaman dilakukan tetapi faktor cuaca dan iklim tetap tak terkendal. Faktor – faktor ini mempengaruhi kuantitas dan kualitas produksi pertanian sehingga produktivitasnya pun diragukan. Sehingga untuk meningkatkan produktivitasnya diperlukan suatu penerapan strategi yang tepat. Strategi yang optimal akan lebih tepat diterapkan jika terdapat temuan terkait pengaruh – pengaruh yang dapat meningkatkan produktivitas hasil panen. Sehingga penelitian ini bertujuan untuk menganalisa pengaruh perlakuan tanam dalam meningkatkan produktivitas hasil panen dengan metode Structural Equation Modeling(SEM). Hasil penelitian menujukkan bahwa penggunaan pupuk memberikan pengaruh signifikan terhadap hasil panen serta perlakuan tanam.
Open Genes — A New Comprehensive Database of Human Genes Associated With Aging and Longevity
Authors: Rafikova Ekaterina , Nemirovich-Danchenko Nikolay , Ogmen Anna , Parfenenkova Anna , Velikanova Anastasiia , Tikhonov Stanislav , Peshkin Leonid , Rafikov Konstantin , Spiridonova Olga , Belova Yulia , Glinin Timofey , Egorova Anastasia , Batin Mikhail
Published: June 2023

The Open Genes database was created to enhance and simplify the search for potential
aging therapy targets. We collected data on 2402 genes associated with aging and
developed convenient tools for searching and comparing gene features. A
comprehensive description of genes has been provided, including lifespan-extending
interventions, age-related changes, longevity associations, gene evolution, associations
with diseases and hallmarks of aging, and functions of gene products. For each
experiment, we presented the necessary structured data for evaluating the experiment’s
quality and interpreting the study’s findings. Our goal was to stay objective and precise
while connecting a particular gene to human aging. We distinguished six types of
studies and 12 criteria for adding genes to our database. Genes were classified
according to the confidence level of the link between the gene and aging. All the data
collected in a database are provided both by an API and a user interface. The database
is publicly available on a website at https://open-genes.org/.
Does the Use of Antenatal Corticosteroids Reduce Respiratory Morbidity in Babies Born in Late Preterm Period?
Authors: Shittu Khadijah A. , Rabiu Kabiru Afolabi , Ahmed Bolaji , Akinola Oluwarotimi I. , Akinlusi Fatimat
Published: June 2023

Objective
The aim of this study is to determine the effectiveness of antenatal corticosteroid in reducing respiratory morbidity in babies born in the late preterm period.
Materials and methods
Two hundred and eighty-six pregnant women at risk of having a late preterm delivery were studied. One hundred and forty-three (143) served as the cases and were given 2 doses of 12mg intramuscular dexamethasone 12 hours apart, while 143 served as the controls and were given a similar quantity of placebo. The women were followed up prospectively and data were collected on the pregnant women and their newborns on a standardized form. The neonates were assessed for acute respiratory distress syndrome and transient tachypnea of the newborn based on clinical signs, symptoms, and chest x-ray results (when indicated). The primary outcome was the occurrence of neonatal respiratory morbidity.
Results
The primary outcome occurred in 5 out of 130 infants (3.8%) in the dexamethasone group and 31 out of 122 (25.4%) in the placebo group (P value = 0.000003). Birth asphyxia, neonatal intensive care admission and need for active resuscitation at birth also occurred significantly less frequently in the dexamethasone group (P value 0.004, 0.009, 0.014 respectively). There were no significant group differences in the incidence of neonatal sepsis, neonatal jaundice, hypoglycemia and feeding difficulties.
Conclusion
Administration of dexamethasone to women at risk for late preterm delivery significantly reduced the rate of neonatal respiratory complications neonatal intensive care unit and need for active resuscitation at birth.
Trial Registration: PACTR (www.pactr.org) Registration Number: PACTR202304579281358. The study was retrospectively registered on April 19, 2023.
Effect on Functional Outcome of Robotic Assisted Rehabilitation Versus Conventional Rehabilitation in Patients with Complete Spinal Cord Injury: A Prospective Comparative Study
Authors: Khande Chandra , VERMA VISHAL , Regmi Anil , Ifthekar Syed , Sudhakar P , SETHY SIDDHARTH , Kandwal Pankaj , Sarkar Bhaskar
Published: June 2023

Study Design: Prospective Comparative Study
Objective:This study aims to compare the functional outcomes of Robotic-assisted rehabilitation by Lokomat system Vs. Conventional rehabilitation in patients with Dorsolumbar complete spinal cord injury.
Methods: 15 patients with Dorsolumbar spinal cord injury with ASIA A neurology were allocated to robotic rehabilitation and 15 patients to conventional rehabilitation after an operative procedure. Pre-rehabilitation parameters were noted in terms of ASIA Neurology, Motor, and sensory function scores, WISCI II score (Walking Index in Spinal Cord Injury score), LEMS (Lower Extremity Motor Score), SCIM III score (Spinal Cord Independence Measure III score), AO Spine PROST (AO Patient Reported Outcome Spine Trauma), McGill QOL score (Mc Gill Quality Of Life score), VAS score (Visual Analogue Scale) for pain and Modified Ashworth scale for spasticity in lower limbs.
Results: On comparing of robotic group to conventional group there was a statistically significant improvement in group in terms of Motor score, WISCI II score, SCIM III score, AO PROST score, Mc GILL QOL score, Max velocity, and Step length. While LEMS score, ASIA neurology, VAS score, Sensory score, and Modified Ashworth scale for spasticity were not statically significant while comparing between two groups.
Conclusion: Robot-assisted rehabilitation is superior than conventional rehabilitation in Spinal Cord Injury patients. Variations in results found in the literature for robotic assisted training are probably a result of factors such as differences in type and severity of lesion, time of onset to entry in rehab the devices used, application of the interventions and control interventions.
Level of Evidence: III