bluuebunny/crossref_metadata_2025 huggingface dataset:
Sifat Mutu Fisik Mi Basah Berbahan Baku Tepung Campolay Masak Penuh
Authors: Aminullah Aminullah , Purba Risdelita , Rohmayanti Titi , Pertiwi Sri Rejeki Retna
Published: October 2020

Buah campolay masak penuh dapat diolah menjadi tepung campolay dan dibuat menjadi mi basah non gluten. Tujuan dari penelitian ini adalah mempelajari pengaruh formulasi rasio mocaf dengan tepung campolay dan konsentrasi guar gum terhadap mutu fisik mi.   Penelitian ini menggunakan dua faktorial, faktor pertama adalah perbandingan mocaf dan tepung campolay (70%:30%, 60%:40%, 50%:50%) dan faktor kedua adalah konsentrasi guar gum (0%, 1%, 2%), dengan dua kali pengulangan. Analisis mi basah meliputi uji cooking loss, kekerasan, kekenyalan, kelengketan. Hasil menunjukkan bahwa semakin banyak tepung campolay yang ditambahkan pada formula mi basah menghasilkan cooking loss semakin tinggi,   tetapi semakin tinggi konsentrasi guar gum yang ditambahkan pada formula mi cenderung   menurunkan nilai cooking loss. Peningkatan konsentrasi  tepung  campolay dan dapat  menurunkan  kekerasan,  akan tetapi tidak berpengaruh secara nyata terhadap kekenyalan dan  kelengketan. Sedangkan peningkatan konsentrasi guar gum dapat menurunkan kekerasan, kelengketan dan meningkatkan kekenyalan mi basah campolay.
KARAKTERISTIK FISIKOKIMIA DAN SENSORI MINUMAN SEREAL INSTAN DARI SORGUM (Sorgum bicolor) DAN TEPUNG TEMPE
Authors: Novidahlia Noli , Kusumaningrum Intan , Pamela Aisyah Intan
Published: October 2020

Penelitian ini bertujuan untuk mengembangkan produk minuman sereal instan dari sorgum dan tepung tempe serta untuk mengetahui dan mempelajari tentang karakteristik fisikokimia dan sensori produk minuman sereal instan dari sorgum dan tepung tempe. Rancangan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan satu faktor dan tiga taraf perlakuan. Faktor perlakuannya adalah perbandingan sorgum dan tepung tempe dengan tiga taraf perlakuan , yaitu (25%:10%), (20%:10%), (15%:15%). Analisis yang dilakukan meliputi uji fisik (daya serap air, waktu rehidrasi, dan viskositas), uji kimia (kadar air, abu, protein, lemak, serat kasar, dan karbohidrat), uji sensori (hedonik). Produk terpilih akan dihitung nilai energi. Berdasarkan hasil data penelitian minuman sereal instan terpilih yaitu perlakuan perbandingan sorgum dan tepung tempe (20%:10%) mengandung daya serap air 269,03 %, waktu rehidrasi 269,50 seconds,  viskositas 6,09 cp , kadar air 4,60 %, kadar abu 3,28 %, kadar protein14,81 %, kadar lemak 14,80 %, kadar serat kasar 2,09 %, karbohidrat 62,85 % , total kalori 444 Kkal.
Pengembangan Lembar Kerja Peserta Didik Berbasis Etnomatematika Pada Materi Segitiga dan Segiempat
Authors: Rewatus Antonius , Leton Samuel Igo , Fernandez Aloysius Joakim , Suciati Maria
Published: October 2020

Penelitian  ini bertujuan untuk menghasilkan produk  Lembar Kerja Peserta Didik (LKPD) berbasis Etnomatematika yang berkualitas baik pada materi Segiempat dan Segitiga.  Untuk mengetahui kualitas dari LKPD yang dihasilkan dilihat dari tiga aspek yaitu kevalidan, kepraktisan dan keefektifan. Metode yang digunakan dalam penelitian ini yaitu research and development(R&D) dengan model pengembangan four-D(4-D) yang dimodifikasi menjadi 3D tahap yaitu define, design, dan develop. Instrumen yang digunakan untuk mengukur kualitas LKPD yaitu angket lembar validasi untuk mengukur kevalidan, wawancara, angket respon guru dan respon peserta didik untuk mengukur kepraktisan, dan tes untuk mengukur keefektifan.Hasil dari penelitian ini menunjukkan kualitas LKPD memenuhi kriteria kevalidan dengan skor rata – rata keseluruhan sebesar 4,8 dan kualitas LKPD memenuhi kriteria kepraktisan dengan skor rata – rata keseluruhan sebesar 4,73 sertapersentase ketuntasan tes peserta didik sebesar 77,7 % memenuhi kriteria keefeektifan.Dengan demikian Pengembangan LKPD berbasis Etnomatematika pada materi segiempat dan segitiga berkualitas baik dan dapat digunakan dalam pembelajaran matematika.
Peningkatan Kemampuan Pemecahan Masalah Mahasiswa DIII Teknik Mesin dengan Software Wolfram Mathematica
Authors: Qurohman M. Taufik , Romadhon Syaefani Arif , Sungkar Muchamad Sobri
Published: October 2020

Dalam penelitian ini populasi adalah Mahasiswa Prodi DIII Teknik Mesin, kemudian untuk sampel yang digunakan adalah kelas 2B yang merupakan mahasiswa semester 2 Tahun Akademik 2019/2020. Penelitian ini memiliki tujuan meningkatkan kemampuan pemecahan masalah yang dengan memadukan teknologi komputasi mengunakan software Wolfram Mathematica. Penelitian merupakan Penelitian Tindakan Kelas dengan 4 tahap yaitu Planning, Acting, Observing, Reflecting. Hasil riset yang telah dilaksanakan dengan aplikasi inovasi pembelajaran komputasi Wolfram Mathematica adalah sebagai berikut : (1) Hasil Rekap kuisioner yang telah dibagikan dan dan di isi langsung oleh mahasiswa memiliki prosentase 24% meningkat menjadi 88% pada siklus ke , (2) Terdapat peningkatan aktifitas belajar mahasiswa dengan diskripsi pada siklus 1 memiliki Prosentase 63% yang memiliki tingkat keaktifan pada tingkat cukup aktif, dan pada siklus II sebesar 75% yang memiliki tingkat keaktifan pada tingkat aktif, (3) Terdapat pula pengingkatan pada kemampuan pemecahan mahasiswa, tingkat keaktifan, dan minat belajar pada mahasiswa yang terlihat dengan indikator perolehan nilai rerata mahasiswa pada siklus 1 sebesar 65 serta tingkat ketuntasan belajar mahasiswa dengan capaian 55%. Kemudian nilai rerata mahasiswa di siklus 2 di peroleh dengan tingkat 77 serta tingkat ketuntasan mahasiswa dalam proses pembelajaran mencapai 98%, sehingga dapat di simpulkan terdapat perubahan positif yang sangat siginifikan dan efektif.
Pengembangan Media Pembelajaran Interaktif Berbasis Strategi Metakognitif untuk Meningkatkan Kemampuan Berpikir Kritis siswa
Authors: Hendi Asrean , Caswita Caswita , Haenilah Een Yayah
Published: October 2020

Penelitian ini bertujuan untuk mengembangkan media pembelajaran interaktif berbasis strategi metakognitif. Media pembelajaran  interaktif ini dikembangkan sebagai penunjang untuk meningkatkan  kemampuan berpikir kritis siswa.  Media interaktif ini berbentuk file persentasi dalam bentuk powerpoint. Model penelitian pengembangan yang digunakan adalah Model DDD-E oleh Ivers dan Barron. Tahapan pengembangan peneltian dimulai dari decide, design, develope, dan evaluate. Subjek penelitian ini adalah siswa kelas X TKJ di SMK Harapan Bangsa Ulubelu Kabupaten Tanggamus, tahun  pelajaran 2019-2020. Data penelitian diperoleh melalui observasi, wawancara, angket respon guru terhadap media pembelajaran, dan tes kemampuan berpikir kritis siswa. Media pembelajaran interaktif yang dikembangkan telah valid menurut ahli media dari segi teori pendukung dan struktur pengembangan media pembelajaran interaktif berbasis metakognitif untuk meningkatkan kemampuan berpikir kritis siswa. Hasil uji di lapangan menunjukkan bahwa kemampuan berpikir kritis siswa yang menggunakan media pembelajaran interaktif berbasis strategi metakognitif lebih tinggi dari pada kemampuan berpikir kritis siswa yang tidak menggunakan media pembelajaran interaktif  berbasis stategi metakognitif.  Oleh karenanya dapat disimpulkan bahwa media pembelajaran interaktif berbasis metakognitif yang dikembangkan lebih efektif untuk meningkatkan kemampuan berpikir kritis siswa.
Praktikalitas dan Efektifitas Bahan Ajar Kalkulus Berbasis Daring Berbantuan Geogebra
Authors: Maskar Sugama , Dewi Putri Sukma
Published: October 2020

Program Pemerintah Republik Indonesia melalui kementerian pendidikan dan kebudayaan (Kemendikbud) tentang pembelajaran daring yang telah digagas tahun 2014 terpaksa dipercepat pelaksanaannya secara masal pada tahun 2020 dikarenakan efek dari pandemi covid-19 yang melanda seluruh dunia, termasuk Indonesia. Perubahan pembelajaran tradisional menjadi full daring tentu menjadi tantangan yang cukup besar bagi institusi penyelenggaran pendidikan. Pembelajaran daring tentu membutuhkan pendukung yang relevan, salah satunya bahan ajar. Artikel ini membahas tentang pengembangan bahan ajar kalkulus berbasis daring berbantuan GeoGebra. Tujuan pengembangan bahan ajar tersebut sebagai alternatif agar pembelajaran kalkulus berbasis daring dapat berjalan efektif dan optimal. Metode yang digunakan untuk mengembangkan bahan ajar tersebut adalah dengan jenis penelitian research and development (R&D) melalui pengujian praktikalitas dan efektfitas bahan ajar dengan instrumen kuisioner dan soal kalkulus dasar pada 20 responden yang merupakan mahasiswa Program Studi Pendidikan Matematika Universitas Teknokrat Indonsesia yang telah mengambil mata kuliah Kalkulus Dasar. Hasil pengujian praktikalitas dan efektifitas bahan ajar ini menunjukan bahwa praktikalitas dan efektifitas bahan ajar ini termasuk kategori baik dengan nilai uji sebesar 3,36 untuk praktikalitas dan 72,75 untuk efektifitas. Artinya bahan ajar kalkulus berbasis daring berbantuan GeoGebra ini dapat diimplementasikan pada pengguna sebagai alternatif pembelajaran kalkulus berbasis daring. Berdasarkan evaluasi hasil kuisioner praktikalitas dan efektfitas bahan ajar ini perlu dipotimalkan lagi pada bagian konten untuk dapat mengembangkan kreativitas pengguna serta pada konten pembelajaran matematika realistik.
Ovarian teratoma with anti-N-methyl-D-aspartate receptor encephalitis, a type of limbic encephalitis: a review of the literature and a case report in Korea
Authors: Park S.H. , Lim J. , Lim K.T. , Choi K.H. , Yoon S.M. , Chung H.J.
Published: October 2020

Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a type of limbic encephalitis that is resulted by an autoimmune processes; it is a rare autoimmune encephalitis caused by the NMDA receptor antibody secreted by all kinds of tumors. This paraneoplastic syndrome is frequently associated with ovarian teratomas; however, neural cells expressing anti-NMDAR may also be involved in the disease. We report a patient with a case of anti-NMDAR encephalitis associated with an ovarian teratoma, and present a literature review of 16 cases of anti-NMDAR encephalitis in Korean women.
Multiple chemical sensitivity (MCS): women’s health issue
Authors: Roncati L. , Vadalà M. , Laurino C. , Palmieri B.
Published: October 2020

Multiple chemical sensitivity (MCS) is a controversial, complex, and recurring chronic disturbance resulting from olfactory exposure at low levels to foreign chemicals usually tolerated in the rest of the healthy population, without functional tests capable to explain signs and symptoms of the disorder. Recently, some authors have supported that organic abnormalities in the olfactory sensors and a hyperactive limbic system, combined with peculiar personality traits, can best explain MCS. Epidemiological observations suggest that MCS has a 2-3% prevalence in the general population and that women are more significantly at risk to develop the disturbance; about 80% of affected patients are in fact women between the ages of 30 and 50. On closer inspection, many women present with hyperosmia during two other common female conditions, i.e. pregnancy and menstrual migraine, both accompanied by well known neurovegetative limbic symptoms; therefore, it appears reasonable to include a hormonal imbalance in the pathogenesis of MCS.
Placenta accreta and uterine rupture of unscarred uterus in patients with systemic lupus erythematosus with prolonged steroid exposure: a report of two cases
Authors: Kim H.M. , Chin Y.J. , Cha H.H. , Seong W.J. , Kim M.J.
Published: October 2020

We experienced two cases of placental abnormalities or uterine rupture in patients with systemic lupus erythematosus (SLE), necessitating cesarean hysterectomy and leading to massive hemorrhage that required large transfusions. So we introduced the possibility of abnormal placentation and uterine rupture as well as preeclampsia, preterm labor, and fetal growth restriction needs to be considered in pregnant women with SLE who have been taking steroids, even if low dose, for prolonged periods and who do not have any other risk factors.
Evaluation of sexual functions and quality of life in female patients after hysterectomy for benign symptomatic diseases
Authors: Can Ö. Koşar , Güler Ö.T. , Çabuş Ü. , Kılıç D. , Kabukçu C.
Published: October 2020

Objective: To evaluate selected quality of life parameters among sexually active patients who underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) for benign symptomatic disease. Materials and Methods: Fifty-six TAH-BSO patients (20 menopausal + 36 premenopausalhysterectomized women) were evaluated between September 2017 and May 2018 using the FSFI, ASEX and SF-36 scores with individual interviews before and six months after TAH + BSO surgery. Results: The preoperative and postoperative period scores from three different validated questionnaires were found to be significantly different for all patients. Scores in the postoperative periods were better in all patients. Also, scores in the preoperative and postoperative periods were higher among premenopausal patients than menopausal patients. Conclusion: Our results showed that sexual function and quality of life improved in all patients who underwent TAH-BSO for benign symptomatic disease. Also, menopausal status is very important.
The role of dinoprostone for labor induction in postterm and high-risk term pregnancies
Authors: Urunsak I.F. , Gulec U.K. , Eser E. , Sucu M. , Akcabay C. , Buyukkurt S.
Published: October 2020

Purpose: To determine the effect of controlled release vaginal dinoprostone (CRVD) in post-term and high-risk term pregnancies on successful ripening, the length of active labour, the total time for delivery, route of delivery, and maternal-neonatal outcomes. Methods: We performed a retrospective study on women undergoing cervical ripening with CRVD. A total of 94 post-term pregnancies (group 1) were compared with 138 high-risk pregnancies requiring labour induction due to maternal and/or fetal indications at term (group 2). The primary outcome of the study was vaginal delivery within 24 hours. Length of active labour, the total time for delivery, route of delivery and maternal and neonatal outcomes were evaluated as secondary outcomes. Results: Vaginal delivery rates were 73.4% (69/94) and 81.9% (113/138) in groups 1 and 2, respectively (p = 0.123). The mean delivery lengths were 16.6 ± 9.5 and 16 ± 8.9 hours in groups 1 and 2, respectively (p = 0.259). Both groups were also similar regarding the length of active labour (9.3 ± 6.7 and 9.6 ± 6.8 hours; p = 0.717). Cesarean section rates were 23.4% and 13% in groups 1 and 2, respectively (p = 0.04). There were no differences in maternal and neonatal outcomes between the groups. Conclusion: Our study showed that dinoprostone is effective for labour induction, particularly in high-risk term pregnancies.
PEMBINAAN TPA/TPQ DI DESA BONTOMATE'NE KEC. TURATEA KAB. JENEPONTO
Authors: Subair
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
A narrative review of newly approved drugs for COVID-19
Authors: Seetharaman Rajmohan , Lokhande Jaisen
Published: October 2020

COVID-19 disease is swiftly spreading over the globe. There were no specific approved drugs or therapies at the start of the pandemic. Hence, the management of these patients involves optimized supportive care. Researchers worldwide are analyzing the viral structure viruses pathophysiology to develop new drugs and repurpose the currently approved drugs. Regulatory authorities worldwide, such as the USFDA, EMA, CDSCO, etc. are working closely with these scientists. They are expediting their efforts by providing advice, technical assistance, regulatory flexibility, and leveraging on scientific information from the trials conducted across various parts of the globe. These efforts have led to emergency use authorizations and restricted emergency use approvals of a few drugs, namely remdesivir, favipiravir, and 2% propofol emulsion for use in COVID-19 patients. The USFDA has revoked the approval of chloroquine and hydroxychloroquine. Many more new drugs are in the pipeline for their antiviral or immunomodulatory or other supportive mechanisms of action. These drugs are under the radar of regulatory authorities who are monitoring their efficacy and safety firmly as the world hopes to find a solution to combat this pandemic.
PEMBINAAN TPA/TPQ DI DESA BONTOMATE'NE KEC. TURATEA KAB. JENEPONTO
Authors: Surianti
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
Resensi Jurnal Bukti Keilahian Yesus Menurut Injil
Authors: Simanjuntak David M. Parsaulian
Published: October 2020

Tulisan ini berisi resensi mengenai jurnal Bukti Keilahian Yesus Menurut Injil yang dituliskan oleh Pdt. Kalis Stevanus., M.Th
Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction in COVID-19
Authors: Senapati Sabyasachi , Banerjee Pratibha , Bhagavatula Sandilya , KUSHWAHA2 PREM PRAKASH , Kumar Shashank
Published: October 2020

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is an emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans-membrane protease serine 2 (TMPRSS2) are the two major host factors that contribute to the virulence of SARS-CoV-2 and pathogenesis of coronavirus disease-19 (COVID-19). Animal to human transmission of SARS-CoV-2 is considered as a rare event that necessarily required strong evolutionary adaptations. Till date no other human cellular receptors were identified beside ACE2 for SARS-CoV-2 entry inside the human cell. Proteolytic cleavage of viral spike (S)-protein and ACE2 by TMPRSS2 began the entire host-pathogen interaction initiated with the physical binding of ACE2 to S-protein. SARS-CoV-2 S-protein binds to ACE2 with much higher affinity and stability than that of SARS-CoV’s. Molecular interactions between ACE2-S and TMMPRSS2-S are crucial and preciously mediated by specific residues. Structural stability, binding affinity and level of expression of these three interacting proteins are key susceptibility factors for COVID-19. Specific protein-protein interactions (PPI) are being identified that explains uniqueness of SARS-CoV-2 infection. Amino acid substitutions due to naturally occurring genetic polymorphisms potentially alter these PPIs and poses further clinical heterogeneity of COVID-19. Repurposing of several phytochemicals and approved drugs against ACE2, TMPRSS2 and S-protein have been proposed that could inhibit PPI between them. We have also identified some novel lead phytochemicals present in Azadirachta indica and Aloe barbadensis which could be utilized for further in vitro and in vivo anti-COVID-19 drug discovery. Uncovering details of ACE2-S and TMPRSS2-S interactions would further contribute in the future research on COVID-19.
PEMBINAAN TPA/TPQ DI DESA BONTOMATE'NE KEC. TURATEA KAB. JENEPONTO
Authors: Ardi
Published: October 2020

Kuliah Kerja Lapang Plus (KKLP) merupakan suatu kegiatan perkuliahan yang bersifat intrakurikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh masyarakat dalam waktu tertentu. oleh karena, sifatnya intrakurikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strata satu (SI) harus mengikuti KKLP.
Laporan minggu ke4 kegiatan 1
Authors: pertiwi
Published: October 2020

Kegiatan pengecetan dan penulisan batas dusun bontoparang dan bontomanai
Melakukan observasi ke tempat kuliah kerja lapang plus di kelurahan Tolo timur
Authors: Meri
Published: October 2020

Observasi dilakukan untuk pengenalan lokasi kelurahan tolo timur
Proses belajar mengajar
Authors: Dinasti Sarmila Dwi
Published: October 2020

Kuliah kerja lapang plus (KKLP) merupakan suatu kegiatan perkeluliahan yang bersifat intrakulikuler dalam bentuk pengabdian pada masyarakat yang dilakukan oleh mahasiswa dalam jangka waktu tertentu.oleh karena,sifatnya intrakulikuler sehingga setiap mahasiswa yang akan menyelesaikan studi di perguruan tinggi pada suatu program strarta satu (SI) harus mengikuti KKLP.
How do loot boxes make money? An analysis of a very large dataset of real Chinese CSGO loot box openings
Authors: Zendle David
Published: October 2020

Loot boxes are a form of video game monetisation that shares formal similarities with gambling. There are concerns that loot box revenues are disproportionately drawn from a small percentage of heavily-involved individuals, as is the case with gambling, leading to the potential for financial harm. In this paper we analyse a dataset of 1,469,913 loot box purchases from 386,269 separate Chinese users of the game Counter-Strike: Global Offensive. The Gini coefficient was used to measure the distribution of spending, and how much spending was concentrated within top percentiles. It estimated the concentration of spending amongst loot box openers as lower than observed elsewhere amongst gamblers (95CI: 63.76% - 64.26%). However, the majority of loot box revenue is drawn from the top 10% of players, with 1% alone responsible for 26.33% of all revenue. Overall, this research provides a crucial first step in understanding the financial consequences of loot box monetisation.
METAPHORS OF DESPOTISM: FROM THE «IRON HAND» TO THE «IRON HEEL»
Authors:   INION RAN, Dushenko Konstantin
Published: October 2020

In the European cultural space there are related metaphors associated with the image of a knight chained in armor: «iron hand», «iron foot/heel», «armored fist», «iron hand in a velvet glove». Most often they are used as a sign of ruthless, despotic power. They are adjacent to the image of «bayonets» as a symbol of despotic power. The article explores the origin and existence of these metaphors in various national cultures.
DEVELOPMENT OF INTELLECTUAL PROPERTY LAW IN THE RUSSIAN FEDERATION
Authors:   MGIMO, Ruzakova Olga
Published: October 2020

This article is about trends and main directions of development of Russian legislation on intellectual property rights, it analyzes the problems of its application in practice and its compliance with international treaties of Russian Federation, in particular, recent changes in legislation relating to the protection of rights to a «live performance», prospects for recognizing geographical indications as intellectual property, the creation of registries of copyright and related rights based on the blockchain technology.
THE TRUTH IS OUT THERE: SEARCHING FOR THE LEGAL NATURE OF DOMAIN NAMES
Authors:   MSU, Loseva Elisaveta
Published: October 2020

The main approaches to domain names legal nature are considered in this article. Each of the positions is critically analyzed. The author suggests that legal nature of domain names should be defined according to their purpose of using and that commercially used domain names should be considered different kinds of intellectual property designators (depending on their contents).
LEGAL ASPECTS OF MODERN BIOTECHNOLOGY
Authors: Kartskhiya Alexander
Published: October 2020

Thanks to modern technologies in the field of artificial intelligence, big data and genetic bioengineering, there are new opportunities to intensify research on genome sequencing (DNA sequencing), editing genes of living organisms. This article is devoted to legal aspects of regulation of biotechnologies, genetic engineering. The author analyzes the possibilities of patent and legal protection of genomic technologies in accordance with the legislation and law enforcement practice of Russia and foreign countries. Biotechnology in the medium term can be an effective tool for the treatment of dangerous diseases and hereditary human diseases, and in the long term - may become a tool for the development of individual abilities to create genetically modified entities («cyborgs»), the legal personality of which in the near future will become relevant topics of legal research.
ETHICAL ASPECT OF ANTI-MONOPOLY IMMUNITY OF THE PATENTEE ON A MEDICINE
Authors: Gosrskaya Ekaterina
Published: October 2020

The article discusses the ethical aspect of the anti-monopoly immunity of the holder of exclusive rights to a drug, and also question about of legality setting the price of drugs by pharmaceutical companies. The author analyzes the role of the state as a balance-guarantor of the interests between citizens, which have the right to affordable and effective medicines, and the companies-patentee as subjects of a business.
SLY DIGIT: UNFAIR PRACTICES IN SCIENTIFIC CREATIVITY
Authors:   INION RAN, Afanasieva Ekaterina , Dolgikh Maria
Published: October 2020

Are mathematical approaches always justified in the case of evaluating the work of scientific and pedagogical workers? What risks does the quote rating carry? What unscrupulous methods are now used to get rid of charges of plagiarism, to wind yourself a scientific quotation rating? Only the scientific community as a whole will be able to work out answers to these and many similar questions, responding to the bad behavior of individual researchers.
LEGAL REGULATION OF USING PHOTOGRAPHIC WORKS AND INTERNET MEMES IN THE MODERN WORLD
Authors:   MSU, Rudenkova Albina
Published: October 2020

Author raises the problem of distinction the concepts of illustrating and citation photographic works. In the article the impact of information technology on the protection and security of internet memes is viewed.
ESTOPPEL IN INTELLECTUAL PROPERTY LITIGATION
Authors:   MSU, Ekimova Vladlena
Published: October 2020

The article deals with licensee estoppel, file wrap estoppel and equitable estoppel in relation to the intellectual property disputes. Firstly, the paper considers negative impact of licensee estoppel on economic. Secondly, the paper analyzes the prosecution history estoppel which often goes hand-in-hand with doctrine of equivalents. Thirdly, the paper describes equitable estoppel as a solution to prevent rent-seeking behavior of owner.
CONSTITUTIONAL GUARANTEES OF PRIVACY IN THE DIGITAL SPACE
Authors: Ivanova Angelina
Published: October 2020

The main problems of privacy and various solutions from the point of view of constitutional rights and freedoms provided in the developed countries of the world are considered.
Von Hippel-Lindau Syndrome- A Case Report
Authors: Thulung Suraj , Baniya Ashish , Paudel Subodh Sharma , Devkota Anirudra , Shrestha Shikher
Published: October 2020

Von Hippel–Lindau (VHL) disease is a rare, familial disorder involving multiple organs, and characterized by the development of many benign and malignant tumors. It is an autosomal dominant disorder with high penetrance and variable expression. We present a case of a 31-year-old gentleman with gradual onset painless bilateral diminution in the vision for one and a half months with significant positive family history. Radiographic study revealed multiple cerebellar hemangioblastomas with obstructive hydrocephalus, renal cortical and pancreatic cysts and cystic renal cell carcinoma. Symptoms were relieved after endoscopic third ventriculostomy. These constellations of findings suggested von Hippel Lindau (VHL) syndrome and we present this case.
Glucose Content in Popular Sweetened Beverages: Soft Drinks, Fruit Juices, Wines
Authors: Adhikari Mandira Pradhananga , Thakur Sunil
Published: October 2020

available with fulltext.
Adsorptive Removal of Cs(I) from Water by Using Persimmon Tannin Impregnated Zeolite
Authors: Paudyal Hari , Pangeni Bimalal , Inoue Katsutoshi
Published: October 2020

available with fulltext
Avaliação de dor em expressão facial neonatal por meio de redes neurais profundas
Authors:   , Buzuti L. F.
Published: October 2020

Neonatal pain assessment might suffer variation among health professionals, leading to late intervention and flimsy treatment of pain in several occasions. Therefore, it is essential to develop computational tools of pain assessment, less subjective and susceptible to external variable influences. Deep learning models, especially Convolutional Neural Networks, have gained ground in the last decade, due to many successful applications in image analysis, object recognitions and human emotion recognitions. In this context, the general aim this dissertation was analyse quantitatively and qualitatively models of Convolutional Neural Networks in the task neonatal pain classification through a computacional framework based in face images of two distinct databases (an international, named COPE, and other national, named UNIFESP). How specific aims were implemented, evaluated and compared the performance of three existent models used in literature: Neonatal Convolutional Neural Network (N-CNN) and two type of ResNet50 models. The quantitative results showed the excellence of N-CNN to neonatal pain assessment automatic, with average accuracy of 87.2% and 78.7% for the databases COPE and UNIFESP, respectively. However, the quantitative analysis showed that all neural models evaluated, including N-CNN models, can learn artifacts from the imagens and not variation discriminating in faces, thus showed the necessity more studies to apply this models in clinical practice
EPOXY POLYMERS BASED ON DIGLYCIDYL ETHERS WITH CYCLIC GROUPS
Authors: Givi Papava  , Nora Dokhturishvili  , Marina Gurgenishvili  , Ia Chitrekashvili  , Zurab Chubinishvili
Published: October 2020

Glycidyl ethers of polycyclic bisphenols of norbornan type and their phenyl substituted derivatives were obtained and studied. They were solidified by diaminodiphenylsulphon and methyltetrahydrophthalic anhydride. The data of the termogravimetric analysis of the obtained polymers showed that they are characterizes by high thermal – and heat stability.The properties of polymers depend on the structure of the hardener and its chemical nature as well. The properties of polymers were sharply changed when glycidyl derivatives of bisphenols were cured by hardeners of different chemical structure. The presence of cyclic structures in the hardener molecule causes considerable increase of their thermal stability. Polymers on the basis of chlorine substituted glycidyl ethers of polycyclic bisphenols are characterized by incombustibility.
An Editorial Passing of the Torch
Authors: Mitchell Kim M. , Zwagerman Sean , Clerc Isabelle
Published: October 2020

None
Methods of assessing the creditworthiness of the natural person borrower
Authors: Kucherenko Svitlana , Kucherenko Oleh
Published: October 2020

The purpose of the study is to analyze the methods of assessing the creditworthiness of the natural person borrower in terms of feasibility of its applying in various types of lending, as well as to provide the recommendations on the most effective method of implementing such an assessment in banking institutions practice.  Both general scientific and special methods of scientific knowledge have become the methodological basis of the article. In the process of writing the article the following methods were used: dialectical, economic comparisons and generalizations, grouping, graphical, system-structural analysis and synthesis. Results of work. In the article the modern methods of assessing the creditworthiness of the natural person borrower used by banking institutions in their practice are thoroughly investigated. The advantages and disadvantages of using each of them and the feasibility of applying different methods in providing various types of loans are substantiated. It is determined that the most promising method of assessing the creditworthiness of the natural person borrower is credit scoring.  The implementation of these recommendations will lead to the improvement and acceleration in providing the quality banking services for the client, as well as to the successful operation of the banking institution. Conclusions. The financial condition of the bank as a whole depends on the quality of assessing the creditworthiness of borrowers. Most often, the examination of the creditworthiness of individual borrowers is carried out on a point system for assessing the clients’ reliability. Based on the analysis of qualitative and quantitative indicators, the bank makes a conclusion about the reliability of a potential borrower and gives the assessment to the creditworthiness of the borrower. In considering the financial situation and economic condition of a potential borrower all the details are important, otherwise the bank may be at risk and suffer great losses. At the same time, the complexity of assessing the creditworthiness of the borrower makes financial institutions to apply the different approaches to evaluation methods. Careful clients’ selection based on the assessment of the borrower's creditworthiness allows the bank to minimize its credit resources loss.
Ensuring the financial probability of the united territorial communities in the conditions of decentralization
Authors: Yevtushenko Natalia , Malyshko Vitalina , Horodnichenko Yuliia
Published: October 2020

Subject of research is the sources of funding for the social development of united territorial communities (UTC). The purpose of the article is to determine the prospects and measures to attract financial resources for the development of local communities in a decentralized environment. Methods which were used in course of research: method of system-structural analysis and synthesis, method of comparative analysis, generalization, statistical, general scientific, special methods of scientific knowledge and other research methods. Study results.The article identifies the main obstacles to effective financial support for the development of territorial communities, considers some experience in finding and raising funds for the development of territories, describes the sources of such funds. Measures that will contribute to the investment attractiveness of the territory are analyzed and substantiated. Application of results. The results of the study can be used by the united territorial communities for the formation of financial resources, as well as in higher education institutions in the teaching of economic disciplines. Conclusions. After conducting the research, it should be noted that the process of uniting territorial communities in Ukraine and, consequently, attracting financial resources to their budgets is a rather complex process and therefore requires consolidation of efforts at all levels of government and support from European partners.  Due to the reform of decentralization of management in Ukraine, capable territorial communities should be created that are able to ensure the development of the territory, quality provision of social services and promote the well-being of their residents and Ukraine in general.  It is determined that the main sources of funds for socio-economic development of UTC are: international technical assistance, additional subventions from the state budget to local budgets for the formation of community infrastructure, local taxes from businesses.
Innovative sources of increasing the competitiveness of rural green tourism enterprises
Authors: Adamchуk Oleksandr
Published: October 2020

The subject of research is the theoretical and practical aspects of the definition and implementation of innovations, forms and directions of innovation in order to increase the competitiveness of rural green tourism enterprises. The aim of the work is to identify innovative sources of increasing the competitiveness of rural green tourism enterprises and substantiate the factors, components and tools for innovation in a knowledge economy, digital technologies, non-cash payments, high-speed Internet. The methodological basis of the article were the theoretical and methodological provisions of modern business economics, historical and monographic methods of scientific knowledge, as well as system-structural analysis and synthesis of the study of phenomena and processes, problem-based approach in justifying types, forms and directions of innovation. Results of work. The sources and offered components, directions and tools of introduction of innovations in work of the enterprises of rural green tourism, including in the form of organizational and administrative, marketing, product groups of them are revealed; in the form of IT startups, touring and digital systems and backup networks; timesharing, clustering, strategic alliances and clubs; smart Internet projects, software organization and management of the actual agro-villages and tourist enterprises in the countryside to increase their competitiveness. Field of application of results. Conclusions and results can be used in the work of rural green tourism enterprises, rural communities, public organizations, local governments; in the educational and scientific process of economic faculties of universities, colleges of tourist specialization, other institutions of higher education. Conclusions. Innovative activity in the system of strategic goals, priorities and guidelines for increasing the competitiveness of rural green tourism enterprises in the era of knowledge economy and digitalization will take a leading place. The realization of their important socio-economic functions, as well as other subjects of social life is becoming increasingly associated with an innovative type of development. In turn, it is based on a continuous and purposeful process of finding, preparing and implementing innovations. The possibility and motivation to obtain higher incomes and the need to increase the efficiency of financial and investment resources forces the participants of the tourism business in the countryside to purposefully create new tastes, interests and needs, introduce fundamentally new products, products, services and technologies. All this is also connected with the acceleration of innovation processes.
Three-Dimensional Biomodels: Use of Different Materials for the Surgical Planning in Relation to Two Mandibular Cysts Cases
Authors: Mariano Astigueta José , Mariano Astigueta José , Norbin José Mendoza Cuello , Alejandro Benitez Javier , Alberto Attaguile , Graciela Ana Giannunzio
Published: October 2020

Introduction: The use of three-dimensional models in the diagnosis, planification and treatment of the
maxillofacial area pathology has been included in publications since 1980, and has enabled to minimize
surgical time, reducing peri and postoperative morbidity, and optimizing surgical results. Currently, the
market offers a huge range of 3D printers and materials which allows biomodels to be printed for medical
purposes. The purpose of the following paper is to describe the use of two types of three-dimensional models
in the therapeutic planning of two cases of mandibular cysts.
Case Report: Two cases of mandibular dentigerous cysts are described, in which osteosynthesis plates were
used to prevent pathological fractures, pre-modeled together with acrylic positioners on three-dimensional
models and printed in different ways. Postoperative clinical and tomographic controls were performed.
Conclusion: The knowledge of the properties of the different materials available for the construction of
three-dimensional models allows selecting the one that best suits the case needs required, minimizing
surgical times and optimizing the results.
Taxonomy of Podoscirtinae (Orthoptera: Gryllidae). Part 8: American taxa of the tribe Podoscirtini
Authors: Gorochov A.V.
Published: October 2020

Tribal position of some American representatives of Podoscirtinae and differences between this subfamily and Eneopterinae are discussed. Two former tribes are reduced to the subtribes Aphonomorphina and Neometrypina (both in Podoscirtini). Two new genera, four new subgenera, 30 new species and two new subspecies are described. The former genus Euaphonus Hebard, 1928 is reduced to a subgenus of the genus Aphonomorphus Rehn, 1903. New replacement name Eneopteroides chopardi nom. nov. is proposed for Eneopteroides flavifrons Chopard, 1956 which is a junior secondary homonym of Eneopteroides flavifrons (Saussure, 1897). Systematic position and distribution of some other American taxa of Podoscirtini are clarified.
The Influence of Restrictive Pulmonary Dysfunction on Osteoporotic Thoracic Vertebral Fractures
Authors: Park Ji-Hun , Lee Sang-Min , Shim Seong-Woo , Baek Sung-Nyun , Choi Yong-Soo
Published: October 2020

Study Design A cross-sectional study. Purpose To examine the influence of restrictive pulmonary dysfunction on osteoporotic thoracic vertebral fractures. Overview of Literature Osteoporotic thoracic vertebral fractures generally result in an increased kyphotic angle, which in turn may lead to pulmonary function impairment. Impaired pulmonary function could be associated with vertebral fractures. However, an association between osteoporotic thoracic vertebral fractures and pulmonary function remains controversial. Methods A total of 96 patients were enrolled in this study, 30 of whom had osteoporotic thoracic vertebral fractures (group 1), 30 with chronic back pain (group 2), and 36 with chronic pulmonary diseases (group 3). Radiologic study of prevalent vertebral fractures, thoracic kyphotic angle, bone mineral density, relaxed expiratory vital capacity, forced vital capacity (FVC), and forced expiratory volume in 1 second (FEV1) in spirometry was investigated. Results The mean FVC and FEV1 were 75.66%±20.23% and 79.93%±22.48%, respectively, in group 1; 84.50%±16.25% and 91.87%±21.65%, respectively, in group 2; and 91.64%±17.53% and 91.03%±23.71%, respectively, in group 3. Group 1 (patients with osteoporotic thoracic vertebral fracture) had the lowest FVC among the three groups (p=0.01). Group 1 revealed worse result of pulmonary dysfunction than group 3 (patients with chronic pulmonary diseases) (p=0.01). The average kyphosis angle of the thoracic spine was 26.95°±15.17°, 36.47°±20.08°, and 28.58°±10.58° in groups 1, 2, and 3, respectively. There was a negative correlation between thoracic kyphosis and FEV1 (r=−0.309, p=0.01). Conclusions The results suggest that osteoporotic thoracic vertebral fracture burden could be affected by restrictive pulmonary dysfunction.
Is Older Age a Contraindication for Single-Level Transforaminal Lumbar Interbody Fusion?
Authors: Patel Jwalant Y. , Kundnani Vishal G. , Chawada Bansari
Published: October 2020

Study DesignRetrospective cohort.PurposeThis study’s primary objective was to compare the clinico-radiological outcomes and incidence of perioperative complications of transforaminal lumbar interbody fusion (TLIF) at lower lumbar levels for elderly and younger patients. The secondary objective was to evaluate the effect of age on clinical outcomes and patient satisfaction in the two groups.Overview of LiteratureThe lumbar interbody fusion surgery in elder age has been reported to produce a higher complication rate and suboptimal results. Literature evaluating efficacy and safety of TLIF in elderly population is scanty. The effect of age on clinical outcome and the overall patient satisfaction after TLIF has been understudied.MethodsThis retrospective study was conducted from 2011 to 2017 with 121 patients, who underwent TLIF and were divided into two cohorts based on age (group A, >65 years and group B, <65 years). Perioperative clinical/radiological parameters, postoperative complications, and satisfactory outcomes were evaluated in both groups. A statistical analysis between two matched groups was performed with logistic regression analysis and Student t-test.ResultsThe mean age was 73.8±4.5 years in group A and 47.3±12.7 years in group B. There was no statistical difference in surgical time (p=0.15), mobilization, or hospital stay (p=0.15) between the two groups. There were no statistically significant differences noted in the Oswestry Disability Index, Visual Analog Scale, or Wang’s outcome score between the two groups at final follow-up. Postoperative complications not affecting outcome were common in the elderly group, but there was no statistically significant difference noted among neurological or cardiopulmonary events between the two groups.ConclusionsIn judiciously selected patients with proper preoperative risk assessment and optimized medical co-morbidities, TLIF surgery can have successful results, in terms of clinical outcome and satisfaction, in the elderly. Older age should not be a contraindication for TLIF in patients with degenerative lumbar disease.
Financer l’éphémère
Authors: Chaney Damien , Pecchioli Bruno
Published: October 2020

Malgré le développement exponentiel du crowdfunding, la mobilisation de la foule pour financer un projet peut représenter un défi lorsqu’il s’agit d’une organisation temporaire comme un festival. Mobilisant la théorie du signal, cette recherche étudie les facteurs clés du succès des campagnes de crowdfunding pour les festivals à partir d’un échantillon de 368 observations. Si les résultats obtenus montrent des similitudes avec ceux observés dans d’autres secteurs concernant les informations liées aux projets, ils mettent également en évidence des spécificités du crowdfunding culturel dans le choix des projets à financer.
Antimicrobial Sensitivity Testing Using the Kirby-Bauer Disk Diffusion Method; Limited Utility in Ugandan Hospitals
Authors: Segawa Ivan , Ssebambulidde Kenneth , Kiiza Daniel , Mukonzo Jackson
Published: October 2020

Background: Antimicrobial resistance (AMR) is a global health threat responsible for increased healthcare costs and mortality. The World Health Organization (WHO) global action plan on AMR recommends antimicrobial sensitivity testing (AST) and surveillance of antibiotic use to address this threat. We conducted a cross-sectional study to determine the utility of AST in three major referral hospitals in Uganda. Methods: We used abstraction checklists to collect data on AST requests, AST performed, AST turnaround time, and dispensed antibiotics, from in-patient files and laboratory and pharmacy records. Antibiotic data were summarized using proportions. The relationship between dispensed antibiotics and AST antibiotic-disks was analyzed using spearman’s rank correlation and simple linear regression. Results: Of the 607 in-patient files reviewed, AST was requested in 24 (4.0%), and done in 13 (2.1%). All three hospitals used the Kirby-Bauer disk diffusion method for AST, with a median turnaround time of 5 days (IQR 4-8). While the frequently used AST antibiotic-disks were cotrimoxazole (13.0%), ampicillin (11.7%), and ceftriaxone (10.5%), the most dispensed antibiotics were metronidazole (30.3%), amoxicillin (19.6%) and ceftriaxone (14.8%). There was a weak correlation (r=0.313, p=0.120) between dispensed antibiotics and AST antibiotic-disks, and AST performance was not associated with antibiotic consumption. Conclusion: We report an underutilization of AST, inconsistent with the hospital antibiotic consumption, and may be related to the use of the disk diffusion method. We recommend alternative faster and better coordination in the procurement of AST diagnostics in Ugandan hospitals.
Pelatihan Komunikasi Efektif dalam meningkatkan Pelayanan Prima di Instansi Pemerintahan Provinsi Jawa Barat
Authors: Ramadhana Maulana Rezi , Sudrajat Ratih Hasanah
Published: October 2020

Ineffective communication will affect the quality of a service, because it is related to the speed and accuracy of information that affects public trust. This issue is a focus on the customer service units of service agencies in the West Java provincial government, so it is necessary to increase the capacity of communication directed at excellent service. Community service activities through this form of effective communication training involve twenty-one employees of the customer service unit. Analyze training effectiveness by using score measurements before and after treatment, and needs response surveys are used to assess the usefulness of the training. The results of the training carried out showed a significant increase in scores between before and after the effective communication training, and the training received a positive response. Associated with the results of the training achieved is expected to have an impact on improving the quality of excellent service.