bluuebunny/crossref_metadata_2025 huggingface dataset:
Aktualne i nowe strategie leczenia aktywnej orbitopatii tarczycowej
Authors: Wierzbowska Joanna
Published: August 2020

Orbitopatia tarczycowa, zwana także oftalmopatią Gravesa, jest następstwem reakcji autoimmunologicznej w oczodole wywołanej przez wspólny dla tarczycy i oczodołu antygen lub antygeny. W niniejszym artykule na podstawie koncepcji patogenezy orbitopatii tarczycowej omówiono aktualną strategię oraz nowe kierunki leczenia zarówno hipertyreozy, jak i aktywnej fazy oftalmopatii. Tradycyjna strategia leczenia orbitopatii obejmuje leczenie immunosupresyjne za pomocą glikokortykosteroidów, radioterapię oczodołów i dekompresję chirurgiczną. Nowe kierunki terapii związane są z zastosowaniem leków specyficznie modulujących określone białka komórkowe zaangażowane w szlaki reakcji autoimmunologicznej w oczodole. Należą do nich przeciwciała monoklonalne, inhibitory cytokin oraz selektywne związki immunosupresyjne.
Perspektywy zastosowania klinicznego nowego implantu RENEXUS® w teleangiektazjach okołoplamkowych typu 2
Authors: Nowosielska Agnieszka
Published: August 2020

Implant RENEXUS® firmy Neurotech Pharmaceuticals należy do nowoczesnych leków okulistycznych zarówno pod względem wykorzystanej w nim substancji czynnej, jak i formy jej podania do wnętrza gałki ocznej.
Substancją aktywną implantu jest rzęskowy czynnik neurotroficzny produkowany przez żywe ludzkie komórki nabłonka barwnikowego zawarte wewnątrz implantu. Rzęskowy czynnik neurotroficzny ma działanie ochronne na komórki siatkówki, dzięki czemu spowalnia ich utratę w przewlekłych schorzeniach degeneracyjnych oraz stanach zaburzonego ukrwienia.
Uważa się, że implant RENEXUS® może być wykorzystany w schorzeniach takich jak: teleangiektazje okołoplamkowe typu 2, zwyrodnienie barwnikowe siatkówki, neuropatia jaskrowa nerwu wzrokowego, przednia niedokrwienna neuropatia nerwu II, degeneracja plamki związana z wiekiem.
Czas aktywnego wydzielania substancji leczniczej do wnętrza gałki ocznej przez implant RENEXUS® ocenia się na ok. 5 lat.
Implant RENEXUS® przeszedł pomyślenie badania kliniczne II fazy i jest obecnie testowany w próbach klinicznych III fazy w leczeniu teleangiektazji okołoplamkowych typu 2.
Energia solar como fator de desenvolvimento rural e a produção de leite em Goiás
Authors: Jordão Luciana Ramos , Silva Thiago Henrique Costa , Chagas Gutherrison Gonçalves das , Barreira Sybelle
Published: August 2020

Este trabalho tem como objetivo geral compreender os desafios para a ampliação do uso de energia solar no Brasil, sobretudo no meio rural e em Goiás, visando promover o desenvolvimento social, ambiental e econômico. Destaca-se a atividade leiteira goiana como objeto de estudo, demonstrando como os produtores, em sua maioria compostos por agricultores familiares, mesmo estando em uma região com grande capacidade de geração de energia fotovoltaica, ficam à mercê das matrizes energéticas tradicionais e não renováveis, como a petrolífera e a hidrelétrica. Por meio de analises documentais e bibliográficas, subsidiadas por análise indireta de dados, em uma perspectiva qualitativa, busca-se compreender as políticas públicas voltadas à promoção do desenvolvimento rural e os entraves para a adoção de uma matriz energética limpa, a solar. Depreende-se que o alto custo para a implantação dos sistemas fotovoltaicos e a ausência de incentivos por parte do poder público são entraves para a autonomia e melhores condições de vida dos agricultores familiares goianos que se ocupam da atividade leiteira como fonte principal de renda. Assim, aponta-se a ampliação do Programa Goiás Solar e a construção de uma agenda de políticas públicas formuladas a partir da necessidade dos sujeitos do campo como saídas para a crise de distribuição energética que assola o estado, gerando um desenvolvimento que expanda as liberdades individuais e coletivas.
Palavras-Chave: Desenvolvimento rural. Energia limpa. Crise energética. Políticas Públicas. Produção de Leite.
Saúde e vulnerabilidade social
Authors: Santos Edemilson Pichek dos , Morais Roberto Tadeu Ramos , Bassan Dilani Silveira Bassan
Published: August 2020

O objetivo geral deste artigo é analisar os indicadores sociais do município de Taquara (Rio Grande do Sul, Brasil) discutindo acerca das intervenções realizadas em uma comunidade em situação de vulnerabilidade social, na perspectiva da saúde, enquanto direito humano fundamental. Como metodologia se utilizou um estudo exploratório-descritivo. Realizou-se um levantamento dos indicadores sociais no município de Taquara, localizado no Vale do Paranhana (RS); a partir da obtenção dos dados, procedeu-se a análise descritiva e, paralelamente, a reflexão com base nas intervenções realizadas. Os resultados permitiram propor dois eixos temáticos, através dos quais foram realizadas as discussões: a) direitos humanos no território dos excluídos: desvelando os indicadores sociais; b) experiência de Intervenções em um território com vulnerabilidades sociais: desvelando a necessidade de práticas de cuidados e cidadania. Por fim, se conclui que a experiência de exercer a saúde no território demonstra que não é possível ignorar outros setores do âmbito social, requer a articulação de vários serviços e esferas governamentais. Faz-se necessária atuação veemente junto às autoridades municipais-regionais para fortalecer a execução de políticas públicas que visem às necessidades da população.
Palavras-chave: Desenvolvimento Regional. Enfermagem. Indicadores de Saúde. Políticas Públicas. Relações Comunidade-Instituição
Relevância econômica dos benefícios previdenciários nos municípios da região COREDE Celeiro/RS
Authors: Kohler Romualdo , Balzan Karine Matuchevski , Ribas João Vitor  Moraes
Published: August 2020

Este artigo tem como objetivo investigar e debater sobre a relevância econômica dos benefícios pagos pela Previdência Social Federal na renda dos municípios brasileiros, em especial nos de pequeno porte. Parte-se da premissa de que no local os fundamentos teóricos diferem-se dos da macroeconomia nacional, por se tratar de uma economia aberta por excelência, com livre fluxo de bens, serviços, rendas, capitais e fatores de produção. Para tal abordagem, epigrafou-se as teorias da Base Exportadora, da Base Econômica e da proposição de Kohler com ênfase na endogeneidade da moeda no território e na diferenciação entre Produto e Renda. Com vistas ao enquadramento metodológico, trata-se de uma pesquisa exploratória, bibliográfica e quantitativa, com o trato estatístico de dados secundários oficiais da Região do COREDE Celeiro/RS, composta por 21 municípios, todos com menos de 25.000 habitantes. Como resultados observou-se a grandeza relativa dos benefícios previdenciários na composição da Renda Municipal, para além da forte correlação, em especial, entre estas transferências públicas e o setor terciário nos municípios amostrais.
Palavras-chave: Renda Municipal. Teoria da Base Econômica. Endogeneidade da Moeda. Benefícios Previdenciários. Desenvolvimento Regional.
Práticas contábeis e a accountability em universidades comunitárias no Rio Grande do Sul
Authors: Thesing Nelson José , Santos Vaneza Lima dos , Büttenbender Pedro Luís , Mera Claudia Maria Prudêncio de , Pieniz Luciana Paim
Published: August 2020

O artigo busca compreender a natureza transformadora/conservadora presente no ambiente universitário, ao verificar, se o trilhar desse caminho, é o de aproximação ou distanciamento da universidade para com a comunidade. Essa inquietação conquista pertinência, nas investigações que buscam compreender as práticas contábeis: Balanço Social, Relatório Social, Relatório de Atividades, elaboração e divulgação dos Relatórios, de como funcionam as lentes dos profissionais da contabilidade, especialmente, seus diálogos com a accountability. O objetivo desta pesquisa foi explorar as práticas operacionais que resultam nas informações necessárias para o accountability nas Universidades Comunitárias do Rio Grande do Sul. O caminho metodológico conta com a abordagem qualitativa, tendo por objetivos as pesquisas exploratória, descritiva e explicativa. A pesquisa verifica, um conjunto teórico, fundamentado na ciência, bem como, conta com a pesquisa de campo, com os responsáveis da contabilidade. Os resultados da pesquisa revelaram que as Universidade desenvolvem um diálogo permanente, fértil para prestação de contas, bem como cultivam, um trabalho estratégico de planejamento, na academia e com os mais diversos setores da sociedade, onde as práticas contábeis se fazem presente, onde o pensar da accountability não é apenas um instrumento mecânico, mas um processo reflexivo a partir do fazer acadêmico, dando sentido para quem produz, em todos os níveis, seja na coleta e mensuração dos resultados, na padronização das informações, na escolha de indicadores, na divulgação dos Relatórios, em processos não só técnicos instrumentais, mas de cunho qualitativo, o que desafia maiores estudos no campo do accountability, bem como, nas vivencias comunitárias e suas repercussões nos processos de desenvolvimento.
Palavras-chave: Accountability. Balanço Social. Universidades Comunitárias. Desenvolvimento Regional.
Vulnerabilidade socioeconômica no semiárido cearense
Authors: Batista Maria Larissa Bezerra , Moura José Ediglê Alcantara , Alves Christiane Luci Bezerra
Published: August 2020

A região do semiárido é vista, em âmbitos acadêmico e institucional, como um território que apresenta históricos recorrentes de vulnerabilidades, sendo esta última entendida como o não atendimento das necessidades básicas à sobrevivência dos indivíduos, que envolve elementos relacionados a saúde, educação, renda e saneamento básico. Com base nisso, tem-se que, nos últimos anos, o semiárido cearense apontou para a necessidade de cuidados específicos, mecanismos de desenvolvimento sociais e econômicos apropriados, além da carência de políticas públicas que atentem para os problemas enfrentados pela região. O objetivo deste estudo é criar um índice que mensure os níveis de vulnerabilidade do semiárido cearense, mediante a proposição do Índice de Vulnerabilidade Socioeconômica (IVSE), a partir da metodologia de Análise Fatorial (AF) e com dados extraídos do Censo Demográfico do Instituto Brasileiro de Geografia e Estatística (IBGE), no ano de 2010. Os resultados apontaram para a criação de três fatores, nomeados de condições socioeconômicas, condições demográficas e condição saúde, respectivamente. Então, conclui-se que existe uma grande heterogeneidade na vulnerabilidade socioeconômica nessa região. Ademais, salienta-se a necessidade de um redimensionamento do papel do Estado em áreas consideradas estratégicas, como a saúde, educação e geração de empregos e renda, tendo em vista que foram identificados níveis altos de vulnerabilidade na região estudada.
Palavras-chave: Vulnerabilidade. Semiárido. Ceará. Análise Fatorial. Desenvolvimento.
Rectal adenocarcinoma following imperforate anus: A rare case report
Authors: Khan Sarah , Khan Hina Abdul Qayoom , Agha Jan Muhammad , Samo Khursheed Ahmed , Abbasi Mujeeb Ur Rehman , Memon Amjad Siraj
Published: August 2020

Background:

Anorectal malformations are a rare presentation. The standard treatment modality for imperforate anus is surgery. The abdominoperineal pull-through procedure was popular in the past for this malformation, but, with recent advancement, the posterior sagittal anorectoplasty and colostomy as a staged procedure are other options. Chronic constipation following pull-through procedures for imperforate anus may also lead to degeneration of the anorectal segment.

Case Presentation:

A 28-year-old male presented with the complaint of on and off constipation and painful defecation since childhood. The patient had a history of imperforate anus congenitally, for which a pull-through procedure was done after birth at another hospital. He underwent multiple surgeries for constipation. During this time period, the patient had constant complaints of difficulty in defecation and constipation, for which he used to use Hager’s dilators to dilate the anal canal. He also used per rectal enema and suppositories. His digital rectal examination showed narrowed anal opening. Colonoscopy was planned, which showed ulcerated and necrotic area at 6–8 cm from anal verge. Biopsy came out to be moderate-to-poor differentiated adenocarcinoma with signet ring cell differentiation. His computed tomography scan was performed, which showed circumferential mural thickening starting from the anal verge to the rectosigmoid junction with local infiltration to prostate, bilateral levator ani, and posterior sacral space. The patient was given a diversion colostomy and was referred for neoadjuvant chemoradiotherapy.

Conclusion:

All patients undergoing pull-through procedures should be closely followed in a multidisciplinary unit with interval colonoscopy for the early detection and prompt management of rectal cancer.
The Great I-QALY Disaster
Authors: Langley Paul
Published: August 2020

The QALY is an impossible construct; it defies common sense. It fails completely once we consider the axioms of fundamental measurement. Utilities as ordinal scales cannot be used to create QALYS. The QALY should never have been introduced to support the value assessment of pharmaceutical products and devices. The result is 30 years of QALY based assessments of pharmaceutical products and devices which are conceptually and technically wrong. They are a charade and will have contributed mistakenly to thousands of formulary decisions. In the search for a common metric to evaluate cost-effectiveness the impossibility of a QALY was overlooked. The result is a disaster, unfolding over decades. Our next steps must be to abandon the QALY paradigm and look ahead to a new value assessment framework.

 

Commentary
Por uma linguística de base antropológica
Authors: Dutra Kedilen , Santana Gabriela Rodrigues , Pozza Mariana Machado
Published: August 2020

A conferência ministrada pelo Prof. Dr. Valdir do Nascimento Flores parte dos conceitos de linguagem, línguas e falante para subsidiar uma Linguística de base antropológica. Assim sendo, o conferencista alicerça-se, fundamentalmente, nos estudos de Humboldt, Saussure e Benveniste, bem como nas indagações epistemológicas de Hagège, Milner e Kant. Tal enquadramento permite que Flores entenda a linguagem como algo que: a) é propriedade humana; b) é realizado nas línguas; c) encontra existência no falante ao ser realizada nas línguas. Assim, o que temos na exposição é uma fagulha para a prospecção de uma Linguística que está essencialmente ligada à natureza do humano e à categoria de enunciação, concebida à luz dos estudos benvenistianos.
A criança entre o falado e o escrito: a aquisição da linguagem e o uso da língua
Authors: Chittolina Raphaela Machado Monteiro
Published: August 2020

A mesa redonda aqui resenhada trata da criança e do uso da língua, mais especificamente da fala, da escrita e de suas relações na aquisição da linguagem. Cada um dos três participantes aborda esse tema com base em uma perspectiva teórica própria: uma abordagem linguística-discursiva (Lourenço Chacon), uma abordagem linguístico-enunciativa (Marlete Sandra Diedrich) e uma abordagem linguístico-funcionalista (Gabriela Maria de Oliveira-Codinhoto). Dado o percurso singular que cada participante trilha para refletir acerca do assunto, constata-se, em todas as pesquisas, um compromisso teórico e metodológico com o estudo da aquisição da linguagem. Tal compromisso se comprova no momento da análise e da discussão dos dados, o que configura cada um dos trabalhos apresentados como uma relevante contribuição para os estudos acerca do uso da língua na constituição da criança como falante e como escrevente.
Arsenic and Other Geogenic Contaminants in Groundwater – A Global Challenge
Authors: Hug Stephan J. , Winkel Lenny H. E. , Voegelin Andreas , Berg Michael , Johnson Annette C.
Published: August 2020

Groundwater is a much safer and more dependable source of drinking water than surface water. However, natural (geogenic) hazardous elements can contaminate groundwater and lead to severe health problems in consumers. Arsenic concentrations exceeding the WHO drinking water guideline
of 10 ?g/L globally affect over 220 million people and can cause arsenicosis (skin lesions and cancers). Fluoride, while preventing caries at low concentrations, has detrimental effects when above the WHO drinking water guideline of 1.5 mg/L and puts several hundred million people at risk
of dental and skeletal fluorosis. In this article, we report on the geochemistry and occurrence of arsenic and fluoride in groundwater and on the development of global and regional risk maps that help alert governments and water providers to take appropriate mitigation measures for the provision
of safe drinking water. We then summarize research on the removal of arsenic and fluoride from drinking water, focusing on adapted technologies for water treatment. Finally, we discuss the applicability of various measures in a larger context and future challenges in reaching the goal of access
to safe drinking water for all.
A Scientific Journey with Ionophore-based Sensors
Authors: Bakker Eric
Published: August 2020

This article describes selected historical milestones in the field of neutral ionophore-based sensors, starting with the first discovery by Wilhelm Simon and their impact to analytical sciences despite the initial difficulty to understand their function. The reader is then guided through
topics in which the author has been involved over the years, from understanding thermodynamic aspects to the field of non-equilibrium potentiometry, polyion sensors, trace level potentiometry, instrumentally controlled ion sensors and finally potentiometry involving local perturbations and
transient currents that allow for new readout possibilities. Discussed applications include clinical diagnostics, environmental in situ sensing/profiling and speciation analysis. The article loosely follows the content of the Simon-Widmer Award lecture of the same title presented by the author
at the CH Analysis 2019 conference in Beatenberg, Switzerland.
[18F]SuFEx Click Chemistry Enabled Ultrafast Late-stage Radiosynthesis
Authors: Zheng Qinheng , Xu Hongtao , Wang Hua , Du Wen-Ge Han , Wang Nan , Xiong Huan , Gu Yuang , Noodleman Louis , Yang Guang , Sharpless K. Barry , Wu Peng
Published: August 2020

The lack of simple, efficient [18F]fluorination processes and new target-specific organofluorine probes remains the major challenge of fluorine-18-based positron emission tomography (PET). We report here a fast isotopic exchange method for the radiosynthesis of aryl [18F]fluorosulfate based PET agents enabled by the emerging sulfur fluoride exchange (SuFEx) click chemistry. The method has been applied to the fully-automated 18F-radiolabeling of twenty-five structurally diverse aryl fluorosulfates with excellent radiochemical yield (83–100%) and high molar activity (up to 281 GBq µmol–1) at room temperature in 30 seconds. The purification of radiotracers requires no time-consuming high-performance liquid chromatography (HPLC), but rather a simple cartridge filtration. The utility of aryl [18F]fluorosulfate is demonstrated by the in vivo tumor imaging by targeting poly(ADP-ribose) polymerase 1 (PARP1).
Spectroscopic and Electrokinetic Evidence for a Bifunctional Mechanism of the Oxygen Evolution Reaction
Authors: Bai Lichen , lee seunghwa , Hu Xile
Published: August 2020

The oxygen evolution reaction (OER) is an essential anodic reaction in many energy storage processes. OER is most often proposed to occur via a mechanism involving four consecutive proton-coupled electron transfer (PCET) steps, which imposes a performance limit due to the scaling relationship of various oxygen intermediates. A bifunctional OER mechanism, in which the energetically demanding step of the attack of hydroxide on a metal oxo unit is facilitated by a hydrogen atom transfer to a second site, has the potential to circumvent the scaling relationship. However, the bifunctional mechanism has hitherto only been supported by theoretical computations. Here we describe an operando Raman spectroscopic and electrokinetic study of two highly active OER catalysts, FeOOH-NiOOH and NiFe layered double hydroxide (LDH). The data support two distinct mechanisms for the two catalysts: FeOOH-NiOOH operates by a bifunctional mechanism where the rate-determining O-O bond forming step is the OH- attack on a Fe=O coupled with a hydrogen atom transfer to a NiIII-O site, whereas NiFe LDH operates by a conventional mechanism of four consecutive PCET steps. The experimental validation of the bifunctional mechanism enhances the understanding of OER catalysts.
A study of Estrogen Receptor, Progestrone Receptor and hER2/NEU expressions in cases of breast cancer in a tertiary care hospital
Authors: Mamta Bharti  , Nanda J. Patil  , Kshirsagar A Y
Published: August 2020

The study of Estrogen receptor, Progesterone receptor and HER-2/neu expressions in cases of ca breast was carried out over a period of 2 years at tertiary care hospital karad which included 101 breast cancer cases. Maximum numbers of patients (34.65%) were in the 41 – 50 years group. All patients were female. Family history was seen in 10 (9.90%) cases. Out of 101 cases equal cases were in the category of invasive breast carcinoma grade -II (46.42%) and grade- III (46.42%).While grade- I tumors comprised of 7.41% cases. Invasive breast carcinoma - no special type accounted for maximum cases (77.22%). Other histological types were medullary carcinoma (7.92%), mucinous carcinoma (2.97%). Out of 101 cases, 56.43% of breast cancer cases were positive for estrogen and progesterone receptors. Maximum number of HER-2/neu over expression 5/10 (50%) was seen in 41-50 years of age group.A positive correlation was found between ER and PR expression. Maximum number of triple negative cases were seen in medullary carcinoma (100%), metaplastic carcinoma (100%) followed by invasive breast carcinoma .Out of 101 cases of breast cancer, 42 cases (41.58%) showed axillary lymph node metastasis. Axillary metastasis was divided as 0 lymph node (no metastasis) - 58.41% cases, 1-3 lymph node metastasis – 21.78% and >3 lymph node metastasis – 19.80%. Tumor emboli were noted in 31.68% of cases. Estrogen and Progesterone receptor expression correlate well with the established prognostic markers like- age, type of tumor, histological grade, axillary lymph node metastasis and tumor emboli.
IMPLEMENTASI DIVERSI GUNA MEWUJUDKAN RESTORATIVE JUSTICE DALAM SISTEM PERADILAN PIDANA ANAK.
Authors: Witasari Aryani , Arif Muhammad Sholikul
Published: August 2020

The research objective is to identify and analyze the implementation of Diversion in order to realize Restorative Justice in the Juvenile Criminal Justice System in an effort to provide legal protection for child criminal offenders. The approach method used in this research is normative juridical or library law research or doctrinal law research, namely legal research by examining library materials and secondary materials, the results of the study found that the obligation to seek diversion with the Restorative Justice approach at every stage in the criminal justice process Children must be carried out in the Criminal Justice System, Diversion as a step towards transferring the settlement of children's cases from the criminal justice process to non-criminal justice processes by prioritizing the Restorative Justice approach which can be carried out by way of deliberation or mediation which emphasizes efforts to restore back to its original state in a friendly manner.
Utilização de 5-fluorouracil (5-FU) tópico em equino com carcinoma de célula epidermoide: relato de caso
Authors: Pinho Neto Antônio Catunda , Viana Vivian , Araújo Magda Lima Chagas , Maróstica Thaire Pereira , Ribeiro Debora Da Silva Freitas , Ribeiro Rodrigo Martins
Published: August 2020

O carcinoma de células escamosas ou epidermoide (CCE) é um uma neoplasia maligna, multifatorial, de origem epidérmica, comum em equinos e responsável por 20% dos tumores dessa espécie.  Nesse contexto, o 5-fluorouracil atua na síntese de DNA e RNA por inibição enzimática, interferindo na replicação celular, sendo indicado nos casos em que há lesões pequenas. Pode ser administrado por via parenteral, tópica ou por injeção intratumoral. O presente trabalho tem como objetivo registrar a ocorrência de um caso de CCE em um equino com lesão ulcerativa extensa apresentando secreção sanguinolenta e purulenta, na região torácica, bem como a evolução do tratamento com o 5-fluorouracil, quimioterapia antineoplásica neoadjuvante, para a remissão da lesão e reduzir a área a ser extirpada com margem de segurança.
Métodos alternativos no tratamento de infecções causadas por Staphylococcus aureus
Authors: Fanin Mauricio , Balestrin Fanin Élister Lílian Brum , Santos Isabela Carvalho dos , Lima Jonathan Soares de , Gonçalves Arianne Peruzo Pires , Martins Lisiane De Almeida
Published: August 2020

Staphylococcus aureus (S. aureus) são agentes causadores de doenças em todo o mundo, que acarretam grandes prejuízos e riscos à saúde humana e animal. Isto ocorre devido à grande capacidade que este micro-organismo possui de adquirir genes que codificam a produção de biofilmes, toxinas e, principalmente resistência a antimicrobianos. Com isso, torna-se muito importante a pesquisa com intenção em encontrar métodos alternativos para o combate a este patógeno. Atualmente, existem inúmeras pesquisas buscando encontrar e/ou desenvolver métodos alternativos frente à utilização de antimicrobianos para combater S. aureus, sendo relatada pela comunidade científica uma grande quantidade de cepas multirresistentes. Dada a grande relevância ao tema envolvendo a saúde única, este trabalho tem como objetivo ressaltar e enfatizar as principais linhas de pesquisa utilizadas atualmente no combate ao S. aureus. As linhas de pesquisa relatadas serão: terapia bacteriofágica; ozonioterapia; homeopatia; atividade de óleos essenciais e extrato de plantas.
Estresse térmico e o desempenho produtivo de ovinos: uma revisão
Authors: Polli Volmir Antonio , Costa Pablo Tavares , Restle João , Bonadiman Rafael , Vaz Ricardo Zambarda
Published: August 2020

O clima interfere de maneira marcante na produtividade animal, característica que tem sua importância ressaltada no tocante às recentes mudanças climáticas verificadas e às previsões de aumento no aquecimento global. Neste contexto, a presente revisão visa abordar os efeitos do clima sobre o conforto térmico, aspectos comportamentais e desempenho produtivo em ovinos. As condições climáticas acarretam respostas fisiológicas e comportamentais relevantes nos ovinos, e, quando essas condições atingem graus elevados de estresse, acabam impactando fortemente nos índices de produtividade. É necessário adequar práticas de manejo, instalações e alimentação de tal forma que permitam melhores condições de bem-estar dos animais frente às condições climáticas estressantes, bem como selecionar biótipos mais adaptados às características climáticas, as quais serão explorados, buscando permitir que expressem todo seu potencial produtivo.
Volarization of valuable compound from watermelon by-product using ultrasound-assisted extraction
Authors: Lim W.Y.C. , Yusof N.L. , M.R. Ismail-Fitry , Suleiman N.
Published: August 2020

The aim of this study was to develop an efficient, reliable, and sustainable technology for
the recovery of value-added compounds from by-product, in this case, is watermelon
rinds. The properties of the watermelon rinds obtained from innovative ultrasoundassisted extraction (UAE) were evaluated. In regard to this, the pectin content, degree of
esterification, and galacturonic acid content of the watermelon rind extracts were
determined in order to verify the efficiency of the UAE. Initially, the UAE were
conducted using two types of acid: citric and hydrochloric. The highest pectin content was
obtained using citric acid. Additional UAE was then performed with citric acid at 50, 60,
or 70°C for 10, 20, or 30 mins. Both UAE temperature and time significantly influenced
the pectin extracts and galacturonic acid. The best findings for a high galacturonic acid
content (47.41%) when the watermelon rinds were extracts at 70°C for 20 mins.
According to the findings, the extraction process lasted 10 or 20 mins at all temperatures
was mainly high-methoxyl pectin, which can form gels under acidic conditions. This
suggests that pectins derived from watermelon rinds using UAE may be especially useful
as an additive in some confectionery products.
Quality assessment of gluten-free bread from pro-vitamin A cassava and velvet bean flour
Authors: Olatunde S.J. , Odebunmi O.F. , Abioye V.F. , Oladimeji T.E.
Published: August 2020

The increasing trend of coeliac disease (CD) and gluten-related disorders has led to
consumers’ increasing interest in gluten-free products with quality characteristics similar
to wheat bread. The potentials of pro-vitamin A cassava and velvet bean in the production
of nutritious gluten-free bread was investigated. Different levels of flour formulations
(100:0, 90:10, 80:20, 70:30, 60:40 and 50:50 (w/w), respectively) were obtained from provitamin A cassava and velvet beans flours while xanthan gum was used as the bread
improver. The effect of the addition of velvet beans flour to pro-vitamin A cassava on
proximate content, anti-nutritional and functional properties of the flour were determined,
while the physical and the sensory properties of the bread samples were evaluated. The
protein, ash, fat and energy values were in the ranges of 1.51- 23.00%, 1.12-3.35%, 2.35-
12.50% and 1555.34-1760 kJ/100 g, respectively. The water absorption capacity, bulk
density, swelling capacity and wettability were in the ranges of 27.69-32.35%, 1.48-
1.61%, 1.01-1.15 g/mL and 9.44-35.19 min, respectively. The values obtained for HCN,
tannin, phytate, Dopamine were 0.64-0.88, 2.22-3.55 mg/100 g, 0.48-1.41 mg/100 g, 0.00-
4.11 ng/mL, respectively. The physical properties ranged 640-980 cm3
, 371-544 g, 1.73-
2.10 cm3
/g and 0.20-1.40 cm for loaf volume, loaf weight, specific volume and oven
spring, while the sensory evaluation indicated better acceptability at 30% velvet bean flour
substitution. This research has shown that nutrient-dense gluten-free bread with acceptable
sensory quality can be produced from pro-vitamin A cassava and velvet beans. This has
potentials to address the coeliac disease.
Marketing Islamic services: tackling misconceptualisation of commercial insurance
Authors: Kadirov Djavlonbek
Published: August 2020

© 2020, Emerald Publishing Limited. Purpose: The purpose of this paper is to offer an alternative conceptualisation of commercial insurance that is based on service thinking and compares it to the ideas flowing from goods thinking that currently appears to be a dominant mindset. Design/methodology/approach: When deliberating on commercial insurance, Muslim jurists and scholars followed a misleading route of logical reasoning that is based on comparing insurance to other approved commercial contracts within Islamic Law. In this paper, the author questions such reasoning by contrasting the framework of service thinking to that of goods thinking. Findings: The alternative framework proposed in this paper repositions commercial insurance as a unique type of service (rather than a good). It shows that commercial insurance can be seen as a bundle of benefits, which unfold in a gradual, intermittent, sporadic manner depending on the circumstances. This mode of a servicing relationship focuses on harm removal rather than the opportunistic actualisation of unfair monetary gain. Insurance premium is conceptualised as an availability fee, while compensation payout is recast as the restoration of value. Practical implications: Muslim jurists and marketing practitioners can use this framework to further scrutinise the permissibility of different varieties of commercial insurance in the contexts of both Muslim and non-Muslim majority countries. As service thinking radically repositions the essence and structure of commercial insurance, the views on the relevance of “gharar” and “riba” may undergo significant re-conceptualisation. Moreover, the design of takaful options can be improved on this basis. Social implications: Service thinking can better elucidate a positive societal role of commercial insurance that is in accord with the societal and Islamic maxim of harm removal. Some objections to commercial insurance relate to public policy failures. Well-regulated commercial insurance industries can substantially contribute to the economic development of impoverished societies. Originality/value: This paper exemplifies compelling power as well as potential of the discipline of Islamic marketing in contributing to significant debates concerning the permissibility of modern commercial options.
Modelling P2P Airbnb online host advertising effectiveness: the role of emotional appeal information completeness creativity and social responsibility
Authors: Wisker ZL , Kadirov Djavlonbek , Bone C
Published: August 2020

© 2019, Emerald Publishing Limited. Purpose: This study aims to examine the factors that influence peer-to-peer online host advertising effectiveness (POHAE). The study posits that POHAE is a multidimensional construct supported by emotional appeal, information completeness, advertising creativity and social responsibility practices influencing purchase intention and positive word of mouth. Perceived value is hypothesised as the moderating variable for the relationship between POHAE and purchase intention. Design/methodology/approach: Quantitative data were collected from New Zealand through a quasi-experimental survey. A total of 95 people participated in the experiment. The study uses one-way repeated measures design ANOVA to test Hypothesis 1 and MEMORE model to test the effects of mediation and moderation for repeated measures. Findings: Results are significant to the study model. ANOVA results show that the assumption of sphericity is not violated: Mauchly’s W, Greenhouse–Geisser, Huynh–Feldt estimates are equal to one, suggesting that the data are perfectly spherical. The mediation and moderation effects for repeated measure designs are also significant. The tests are based on 95 per cent Monte Carlo confidence interval and 20,000 bootstrapping samples. Research limitations/implications: This study enhances the hierarchy of effects theory (HOE) (Lavidge and Steiner, 1961), which posits that consumers respond to a specific marketing communication through three components: the cognitive component, which is measured by an individual’s intellectual, mental or rational states; the affective component that refers to an individual’s emotional and feeling states; and finally the conative or motivational state, that is, the striving state relating to the tendency to treat objects as positive or negative. This study observes significant paths from POHAE to purchase intention and word of mouth. Limitations include a small sample size (95) and not regressing the POHAE variables individually on purchase intention and word of mouth. Practical implications: Given the absence of a brand, as in the Airbnb host advertisement, attention should be given to writing the adverts effectively. Advertising creativity does not only hold for graphics and personal pictures but also for the hosts who need to be creative in crafting their advertisement text. Elements such as social responsibility practice and creativity should also not be overlooked. Social implications: This study provides insights on how to effectively communicate with potential customers in a peer-to-peer marketplace. Originality/value: This study provides an insight into peer-to-peer marketplaces on the importance of marketing communication strategies by providing more attention to writing advertisement texts. It is important to understand the variables that influence consumers’ motivation in responding to Airbnb online advertisements.
Big data approaches and outcome of information asymmetry: opportunities for future research
Authors: Mandlik Milind A , Kadirov Djavlonbek
Published: August 2020

No description supplied
Tackling the Subaltern Quandary: Marketing Systems of Dignity
Authors: Jagadale SR , Kadirov Djavlonbek , Chakraborty D
Published: August 2020

© 2017, © The Author(s) 2017. The subaltern quandary refers to the failure of a fast-growing economy to improve the abysmal living conditions of marginalized groups. To gain a better insight into this issue, we investigate the subaltern group’s experiences of marketing systems in the context of neo-liberal reforms in rural India. The qualitative analysis of subaltern narratives shows that subaltern experiences are shaped by marketization processes that imbue market relations with new stylized meanings of dignity. Despite these meanings perpetuating limited and distorted constructions, subalterns use them, exemplified in their attempts to minimize their perceived dissimilarity to other marketing system actors, in order to gain access to predominant, albeit flawed, marketing systems. Thus, the status quo is rarely challenged. This research suggests that the subaltern quandary can only be resolved when market development initiatives take human worth as a main goal, while subalterns are empowered with market system creation, design and governance capabilities.
Investigating Chrematistics in Marketing Systems: A Research Framework
Authors: Kadirov Djavlonbek , Varey RJ , Wolfenden S
Published: August 2020

© 2015, © The Author(s) 2015. Contributing to the analytical capacity of critical thinking in macromarketing, we develop a research framework that would enable researchers to investigate chrematistics in marketing systems. Chrematistics refers to regulative influences on marketing systems’ structure and operations of market action perpetuated by actors with power/dominance. We outline the research framework consisting of a seven-step process that helps to scrutinize the transformative effect of chrematistic practices on the design and regulation of marketing systems.
Authenticity: A Macromarketing Perspective
Authors: Kadirov Djavlonbek , Varey RJ , Wooliscroft B
Published: August 2020

This investigation argues that authenticity is inherently a macromarketing concept that is linked to how marketers and consumers view themselves and their own status in society. We show that authenticity refers to the marketer's marketplace condition (mindset) that can be best described as sincere concern for another. We argue that micromarketing as a general phenomenon is rooted in inauthenticity due to the fact that micromarketing practices represent (distressed, decomposed) overreaction to the marketers' self-embraced narrow view of their own social status (as maximiser of self-interest, profit, growth) that is largely irrelevant - even contradictory - to the crucial goals of society. © The Author(s) 2013.
The companion community: How car producers promote hybrid car consumption
Authors: Kadirov Djavlonbek , Varey R
Published: August 2020

No description supplied
Customers of place: Exploring interregional migrant collectivities
Authors: Kadirov Djavlonbek , Triveni A
Published: August 2020

Purpose – The aim of this research is to explore how and why different migrant groups see different values in places they move to. Understanding these values and also the conditions in which these values are shaped will help in targeting marketing effort. Design/methodology/approach – The hierarchical and K/means cluster analyses were instrumental in identifying different migrant clusters. Planned contrasts were employed to compare related pairs of clusters. The logistic regression analysis identified several determinants of cluster membership likelihood. Findings – Four different internal migrant clusters are identified in the Hawke's Bay region of New Zealand. These are Material Success Seekers, Community/Environment Folks, Apathetics, and All/rounders. The former two express a fragmentalist lifestyle. Material Success Seekers emphasise regional business opportunities while being indifferent to social and natural resources. In contrast, Community/Environment Folks emphasise social and natural resources while maintaining indifference to business opportunities. In turn, the latter two clusters make up a holistic lifestyle: All/rounders consider all three major characteristics of the region to be important while apathetics totally deemphasise these characteristics. The planned contrasts show that demographics are instrumental in predicting differences between related clusters but not helpful in distinguishing the identified lifestyles. Research limitations/implications – The limitation of this investigation is that the important constructs used to cluster migrants are not well calibrated, although the reliability scores appear to be satisfactory. Moreover, the use of four/point importance scales does not allow attaining a greater level of construct sensitivity. The research method is unique in a sense that the cluster analysis and the planned contrasts are applied to examine contrasting values of migrant collectivities. Practical implications – A number of specific practical challenges need to be resolved by the regional decision makers in order to enhance place satisfaction by internal migrant collectivities. First, the regional and city councils will need to tailor different services, facilities, and public spaces to appeal to different requirements of migrant clusters. Second, the region's settlement support agency should provide migrants with relevant, focused, and differentiated information about available services and resources to suit their various life goals, aspirations, and values. Originality/value – This investigation tackles the problem of lacking theoretical and empirical research foundation on internal migration as a marketing phenomenon. Moreover, it is unique in its approach of conceptualising migrant segments as cultural phenomena, that is, interdependent collectivities that form on the basis of contrasting values. © 2010, Emerald Group Publishing Limited
Macro-systems role of marketing: Do we trade environment for welfare?
Authors: Kadirov Djavlonbek
Published: August 2020

The purpose of this research is to advance understanding of the macro-systems role of marketing. The author augments the equivocal principle of marketing (EPM) with the hypothesis that marketing has a negative indirect impact on societal welfare. The estimation of a structural error correction model in the context of the U.S. marketing system confirms that there exists a negative long-run relationship between environmental entropy and sustainable welfare with marketing positively associated with environmental entropy. This fact invalidates the assumptions behind the trade-off conjecture, which could only be supported if one is willing to accept the economic welfare myth. © SAGE Publications 2011.
The effect of an educational intervention on awareness of various aspects of pulmonary tuberculosis in patients with the disease
Authors: Yousif Kalthoum , EI Maki Mabrouka , Babikir Rosa Khalil , Abuaisha Hasan
Published: August 2020

Background: Tuberculosis (TB) is a major health problem worldwide. Raising awareness of various aspects of the disease among patients who have TB is important to help in control and prevention. Aims: This was a quasi-experimental study, pre- and post-test, designed to evaluate the effect of an educational intervention on awareness among patients with pulmonary TB. Methods: A structured questionnaire covering various facts about pulmonary TB was used in the pre-intervention phase for 150 TB patients who were being followed-up in a major hospital in Sudan (r = 0.80). The same questionnaire was reused after the patients underwent an educational awareness programme. Results: There were more males (74%) than females. Mean age was 36.5 years. Most patients (86.6%) had some education, however, their knowledge about aspects of TB was generally poor prior to the intervention. This included the nature of the causative organism, modes of transmission and measures needed for the control and prevention. Post-intervention, there was significant improvement in all aspects of knowledge tested (P < 0.007). Conclusion: Although the diagnosis of TB in the participants was confirmed and they were on regular clinical follow-up, their knowledge about various aspects of TB was poor prior to the educational intervention. There is a need for more effort towards raising awareness among patients with TB about their disease while on treatment. This is important to help control and prevent the disease
MEASURING SUSTAINABILITY PERFORMANCE IN UNIVERSITY: IS IT POSSIBLE TO IMPLEMENT SUSTAINABILITY ACCOUNTING IN PUBLIC SECTOR ORGANIZATION?
Authors: Kurniawan Putu Sukma
Published: August 2020

This study aims to identify the ability of non-business organizations to implement the concept of sustainability accounting and to measure the organization’s sustainability performance. The object of this study is higher education institutions (public universities). This study used a qualitative paradigm with data collection techniques and using the document analysis method. The data used is the university’s sustainability report and relevant documents. The methods used to analyze sustainability performance is the GASU method and the STARS System. The results of this study found that public university organizations can apply the concept of sustainability accounting and have a very high capability to implement the concept of sustainability accounting. This study also identified the challenges in the implementation process of sustainability accounting in public sector organizations, particularly in higher education institutions.
EXPLAINING EXISTING PERFORMANCE OF INDONESIA’S AUDIT BOARD: INFORMAL NETWORKS, CONSTITUTIONAL MAKERS’ DECISION, AND CONSTITUTIONAL REFORM
Authors: Baidhowah Adfin Rochmad
Published: August 2020

This study seeks to explain the process of Audit Board article amendment in the constitutional reform as the source of current BPK’s performance, by answering questions: how much do informal networks influence constitutional maker’s decision and to what extent do the external pressures influence the informal networks on the amendment of Audit Board article? This study used a quantitative method to develop variables of social networks in examining how much informal networks based on ideational informal networks influence constitutional makers’ voting between 1999 and 2001 in six meetings which contained voting out of 39 meetings of the Audit Board article amendment. Illustrating statistically significant results of the influence of ideational informal networks on the constitutional makers’ decisions and the influence of high political effect (president’s preference) and strong party pressure on the ideational informal networks, this study shows that “the progressive liberal bloc” which can enforce constitutional reform – particularly Audit Board article though not full-scale reform – within the “ineffective formal institution” as it happened in transition era, has shown how informality’s outcome is in line with formality’s outcome, so it causes improved performance of Audit Board today. Because the statistical evidence talks to broader topics about the people representative bodies and governance, this study suggests paying more attention to the factors of constitutional makers’ networks, on and off the meetings of constitutional reform.