bluuebunny/crossref_metadata_2025 huggingface dataset:
SUPERVISI VIRTUAL PROGRAM PENGENDALIAN TUBERKULOSIS PARU ERA PANDEMI COVID-19 DI KABUPATEN OKU TIMUR
Authors: Siti Patria Hutami  , Yodi Mahendrahata  , Diah Ayu Puspandari
Published: May 2023

Background: COVID-19 requires all parties to adapt to an unprecedented situation. Meanwhile, the implementation of the Pulmonary TB Control Program activities must continue to support the success of the Pulmonary TB Control Program in East OKU Regency. Coaching which is usually done face-to-face but is now very difficult

to do because the COVID-19 has not subsided. Modern technology that reaches all aspects of life, including supervision activities.

Objective: To describe the virtual supervision mechanism carried out by the Regional Health Department to the primary health care during the Covid-19 pandemic in the Pulmonary TB Control Program in East OKU Regency.

Methods: A descriptive case study approach through a single case holistic design. Qualitative information was obtained through in depth interviews and documentation studies on April-Mei 2021. The research subjects were taken by the purposive sampling method. The subjects were 16 people.

Results: The implementation of virtual-based supervision activities was carried out via WhatsApp and telephone from the Regional Health Department to the primary healthcare. Virtual supervision made it easier to access communication between the Health District Office and the TB Program Manager at the puskesmas because

there are no restrictions on funds, distance and time. The Health District Office were able to monitor MSS achievements through the SITB report and monitor the availability of drug stocks virtually through coordination with the TB Program Manager at the puskesmas. However, the Health District Office was unable to monitor the use of logistics and reports related to slide numbering at the puskesmas in addition to the limited guidance provided during the COVID-19 pandemic.

Conclusion: Social media is used as a means of exchanging data and information. Virtual monitoring of activities and coaching has not been carried out optimally. Coaching needs to be done virtually to improve the ability and skills of a TB Programmer in terms of recording and reporting TB programs during the pandemic of COVID-19.
KUNJUNGAN RUMAH SEBAGAI STRATEGI PENINGKATAN PELAYANAN KESEHATAN UNTUK KELUARGA RAWAN DI KOTA MATARAM (WILAYAH KERJA PUSKESMAS KARANG PULE)
Authors: Yatik Krisliani  , Mubasysyir Hasanbasri
Published: May 2023

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DXVNet-ViT-Huge (JFT) Multimode Classification Network Based on Vision Transformer
Authors: Li Haoran , Li Daiwei , Zhang Haiqing , Luo Xincheng , Xu Lang , Qu LuLu
Published: May 2023

Aiming at the problem that traditional CNN network is not good at extracting global features of images, Based on DXVNet network, Conditional Random Fields (CRF) component and pre-trained ViT-Huge (Vision Transformer) are adopted in this paper Transformer model expands and builds a brand new DXVNet-ViT-Huge (JFT) network. CRF component can help the network learn the constraint conditions of each word corresponding prediction label, improve the D-GRU method based word label prediction errors, and improve the accuracy of sequence annotation. The Transformer architecture of the ViT (Huge) model can extract the global feature information of the image, while CNN is better at extracting the local features of the image. Therefore, the ViT (Huge) Huge pre-training model and CNN pre-training model adopt the multi-modal feature fusion technology. Two complementary image feature information is fused by Bi-GRU to improve the performance of network classification. The experimental results show that the newly constructed Dxvnet-Vit-Huge (JFT) model achieves good performance, and the F1 values in the two real public data sets are 6.03% and 7.11% higher than the original DXVNet model, respectively.
An Empirical Study on Why People in Haryana Are Preferring Startup in Todays Era and The Challenges Faced
Authors: Gera Tushar , Miglani Assistant Prof. Mehul
Published: May 2023

Abstract: The term "startup" is the most buzzed word in the 21st century. It significantly affects the nation's economy. A startup is a young business founded by one or more entrepreneurs to produce distinctive and one-of-a-kind goods or services. It seeks to promote innovation and accelerate the development or standard of living of the society. Entrepreneurship, self-employment, and enterprise development can help to tackle the crisis of unemployment and slow economic growth. However, those that choose one of these three options need to overcome a number of obstacles, and such start-up businesses have a high failure rate. Lack of funding, price increases, and drawbacks from small scale economies are what led to the failure. The startup entrepreneurs were called in order to investigate the startup environment, problems, possibilities, and challenges they confront as well as their familiarity with governmental rules. The focus of the study was on how businesses see their journeys with particular reference to the startup scene in Haryana.
Community Blogs Implementation for an Organization
Authors: Deshpande Roopa Onkar
Published: May 2023

Abstract: Community-based blogging sites can be excellent resources for knowledge on a wide range of specialized subjects. Such systems' usefulness significantly depends on user participation and contribution. In addition to offering information and resources on specialized subjects. These websites can promote a sense of belonging and support, and they can be a great place to gather advice and information on particular subjects.
NFTs in AR
Authors: Singh Amulya , Bhatnagar Aayushi , Bhatnagar Kartikey , Kumar Dr. Rajesh
Published: May 2023

Abstract: In the real world, we enjoy showing off our art collections through images and films to express our personalities and interact with others in the neighborhood. However, there aren’t many methods in the NFT community outside updating the profile image for us to show others how much we love our collections. Adding any NFT to your camera is quite simple with this project. This merely needs an OpenSea connection to access the associated material because of the compatibility with web3. And whether it is 3D or 2D, a superb AR experience will be created based on the NFT. The NFT can be used as a background if it’s a JPEG. However, if the 3D model is set up, you may control it by moving your body.
Enhancing Product Trust Using Blockchain
Authors: Bhosale Sahil , Bhosale Aditya , Nair Sreerag , Mohan Arjun , Patil Prof. Anita
Published: May 2023

Abstract: Counterfeit products have become a major issue in the global market, causing significant economic losses to businesses and health and safety risks to consumers. Blockchain technology has the potential to address this problem by creating a secure and immutable record of the origin and movement of products. This paper explores the use of blockchain technology for identifying counterfeit products. We examine the characteristics of blockchain technology, its benefits, and limitations. We also discuss the current approaches used for product identification and how blockchain technology can be used to enhance these methods. We present a case study on how blockchain technology can be implemented to identify counterfeit pharmaceuticals, one of the most critical areas of concern. The results show that blockchain technology can be a useful tool in identifying counterfeit products, as it provides an immutable record of product provenance, enhances traceability, and reduces the risk of fraud.
Profil Darah Merah dan Bobot Badan Ayam Broiler dipelihara pada Ketinggian Tempat yang Berbeda
Authors: Habibi Badru Zaman , Wahyuni Hanny Indrat , Widiastuti Endang
Published: May 2023

The aims of this research was determine the difference in the profile of red blood and body weight of broilers kept in the highlands and lowlands. The material of this study used 40 starter and finisher period chickens aged 21 and 35 days. The parameters observed were the profile of red blood and body weight. Data were analyzed using a t-test to test an average of 2 populations. The results showed that differences in place height were not significantly different (P> 0.05) in the number of erythrocytes and hemoglobin but were significantly different (p <0.05) in hematocrit and body weight. The conclusion of this study the profile of red blood broilers kept at different altitudes is still normal under the erythrocyte and hemoglobin level but the increase in temperature in the lowlands increases hematocrit values and decreases production seen from the body weight of broilers falling below normal.
Changes in ammonia emmisions in different zonation on closed house in the dry season affects Broiler chicken meat quality
Authors: Diyantoro Fahmi Aditya , Sarjana Teysar Adi , Sarengat Warsono
Published: May 2023

This research is an applied research carried out in broiler closed house with the aim of assessing the effect of ammonia emissions levels in different zones which affect the broiler meat quality in the dry season. Seven hundred and twenty broilers which taken from a portion of population in closed house with a capacity of 11.000 were used. The treatment applied is a change in ammonia emissions at a different zones which is measured on 0, 1/4, 1/2, and 3/4 length of broiler house from inlet. The parameters observed were pH, color and Water Holding Capacity (WHC) of broiler chicken meat. The results obtained indicate that an increase in ammonia emissions on zones 3 and 4 significantly affecting the increase of WHC value in zones 3 and 4 while other parameters do not. The increase of WHC value was an indicator of the decrease in broiler meat quality. It was concluded that the increase in ammonia emissions in zones 3 and 4 decreases the meat quality in the form of changes in the value of WHC without affecting pH and color values of broiler chicken breast meat.
¿Diagnóstico o estigma? Problematizar la enfermedad desde un acercamiento duoetnográfico
Authors: Aranda Delgado María Magdalena , Acosta Álvarez Mariely , Bénard Calva Silvia Marcela , Luna Blanco Mónica Adriana
Published: May 2023

Objetivo: El propósito de este escrito es hablar sobre las construcciones socioculturales alrededor de la enfermedad. La principal preocupación es contribuir a desmontar desde nuestras vivencias como investigadoras y mujeres diagnosticadas, el estigma que impregna la vida cotidiana de las personas como nosotras: obesas o con VPH (virus del papiloma humano). Metodología: Mediante la metodología conocida como duoetnografía, en la que dos individuos narran experiencias compartidas para profundizar sobre un fenómeno sociocultural, presentamos una serie de cavilaciones que cuestionan el lugar social en el que se nos coloca al ser valuadas como enfermas. Resultados: Encontramos, a partir de nuestras reflexiones simultáneas, tres epifanías que se relacionan, primero, con el estigma biomédico, luego, con el estigma personal y, después, con el estigma sociocultural. Una cuarta epifanía expone las consideraciones de aprendizaje conjunto durante el proceso de convivencia académica de las autoras. Conclusión: Nos interesa, sobre todo, dejar una invitación a considerar críticamente el estigma, nos preocupa hablar de cuidado y apuntar las prácticas discriminatorias más que negar nuestros diagnósticos.
Diyetsel Gümüş Nanopartikülün Gökkuşağı Alabalığının (Oncorhynchus mykiss) Yetiştiricilik Parametreleri ve Yüksek Sıcaklık Toleransına Etkisi
Authors: Uçaş Özgür , Evliyaoğlu Ece , Sevgili Hüseyin , Akarsu Esin , Noor Izam Siti Nur Insyirah , Yılmaz Hatice Asuman , Eroldoğan Orhan Tufan
Published: May 2023

Son yıllarda balık yemlerinde kullanılan balık unlarının yerine bitkisel protein kaynaklarının kullanılması ile birlikte balıklar için esansiyel olan mikro elementlerin yem içerisindeki miktarları da oransal olarak azalmıştır. Bu sebeple, kritik seviyelerde kullanılması gereken bu mikro besinlerin nanopartikül formlarının, özellikle soğuk su balıklarında kullanımının araştırılması önem arz etmektedir. Bu çalışmada yemlere ilave edilen gümüş nanopartikülün (Nano-Ag) gökkuşağı alabalığının (Oncorhynchus mykiss) büyüme, yem alımı, tüm vücut besinsel kompozisyonu ile kritik termal maksima değeri üzerine olan etkileri araştırılmıştır. Denemede 3 farklı dozda (0, 0.2 ve 2 mg/kg) Nano-Ag içeren yem hazırlanmıştır ve başlangıç ağırlıkları 41,50,31 g olan balıklar bu yemler ile 60 gün süresince günde iki defa olacak şekilde beslenmişlerdir. Deneme sonunda, alabalıkların final ağırlıkları 118,9 ve 112,9 g arasında değişmiş, gruplar arasında istatistiki önemli bir farklılık bulunmamıştır (P>0.05). Aynı şekilde, canlı ağırlık kazancı, yem tüketimi, yemden yararlanma oranı, visero-somatik indeks ve hepato-somtik indeks açısından da gruplar arasında istatistiksel olarak önemli bir farklılık bulunmamıştır (P>0.05). Gruplar arasında tüm vücut ham protein içeriği %16,1-16,3 arasında değişirken lipit içeriği %11,4-12,2 arasında değişim göstermiştir (P>0.05). Deneme sonunda gerçekleştirilen kritik termal maksima (CTMax) denemesinde yemlere ilave edilen Nano-Ag’nin önemli düzeyde istatistiki bir etkisinin olmadığı gözlenmesine karşın (P>0.05), yüksek Nano-Ag’nin termal toleransı kısmen de olsa artırdığı gözlenmiştir. Kontrol, 0.2 mg/kg ve 2 mg/kg grubu bireylerinin ortalama CTMax değerleri sırasıyla 27.0°C, 27.2°C ve 27.8°C olarak belirlenmiştir. 2 mg/kg Nano-Ag’nin CTMax’ı %3 artırdığı gözlenmiştir. Bu çalışma ile yemlere ilave edilen Nano-Ag’nin gökkuşağı alabalıklarında büyüme performans verilerine ve yem alımına etkisinin olmadığı ancak kısmen de olsa CTMax değerini artırma eğiliminde olduğu ortaya konmuştur.
Videogames e interações: intersecções entre a comunicação e a educação, segundo a perspectiva sistêmica e a ecologias das mídias
Authors: Da Silveira Bezerra Wagner
Published: May 2023

Considerando o consumo de videogames fenômeno social relevante, neste artigo, baseado em revisão bibliográfica que constituiu um dos capítulos da tese de doutorado que buscou compreender a produção de sentidos resultantes de interações experienciadas através dos jogos de videogames, on-line e off-line, a partir de grupos focais, recorro à interseccionalidade como perspectiva metodológica para demonstrar as intersecções entre a Comunicação e a Educação, à luz da perspectiva sistêmica e da ecologia das mídias, na ótica de pensadores como Gregory Bateson, Marshall McLuhan, entre outros. Na conclusão, assinalo que nas mídias se constituem linguagens que codificam a realidade, organizando-a segundo critérios e ideologias próprios, capazes de transformar e ser transformados por seus/suas usuários/as.
Telejornalismo, cultura e mortes do meio político: apontamentos sobre transformações do Jornal Nacional
Authors: Negrini Michele , Copetti Dalmaso Silvana
Published: May 2023

A morte é um assunto que faz parte do cotidiano humano e que adentra na pauta dos mais diversos meios de comunicação, como a televisão, por meio dos programas telejornalísticos. No âmbito do telejornalismo, que tem passado por ressignificações de ordem social e cultural no decorrer do seu processo histórico, as coberturas de mortes podem ser tomadas como objetos para visualização dessas transformações. Desta forma, o foco deste artigo é observar, através de verificação de reportagens sobre mortes do meio político no Jornal Nacional, as transformações do subgênero telejornal. Vamos tomar como base teórica a discussão de gênero televisivo como categoria cultural (MITTELL, 2001), considerando o gênero televisivo como uma chave analítica para o estudo. A pesquisa tem caráter exploratório e observacional (GIL, 2008).
Cinema caboclo manauara: na encruzilhada de imagens e sons produzidos em escolas
Authors: Menezes George Augusto Silva de , Silva Renata Ferreira da
Published: May 2023

Este artigo objetiva identificar e catalogar audiovisuais produzidos por um projeto em escolas públicas de Manaus entre 2007 e 2014. A catalogação parte do cinema de borda (LYRA, 2009) e da pedagogia da encruzilhada de Rufino (2019). Metodologicamente, a pesquisa se divide em três etapas: a) coleta de produções audiovisuais; b) catalogação e disponibilização dos materiais; e c) produção textual com considerações teóricas a partir de Didi-Huberman (2012), Francez (2021), Wunder (2016), Migliorin e Pipano (2018), Quijano (2005), Dussel (1993) e Walsh (2013, 2019). Como resultado, constatamos que a produção do projeto trouxe novas perspectivas sobre os modos de se "fazer cinema na escola", reforçando a potência de um audiovisual periférico em pesquisas decoloniais em torno de um cinema caboclo manauara.
Enhancing Photodetection Efficiency of CMOS SiPMs using Virtual Guard Rings in a Standard 0.35 μm Process
Authors: Preitnacher Jonathan , Ageev Sergei , Hansch Walter
Published: May 2023

In this letter, we introduce a design of virtual guarded SiPMs
fabricated in a standard 0.35 μm standard complementary metal oxide
semiconductor (CMOS) process. We compare the performance of these
virtual guarded cells (VGC) to that of conventional cells with real
guard rings, referred to as physical guarded cells (PGC). Specifically,
we evaluate the photon detection efficiency (PDE) of both types of
SiPMs. Our results demonstrate that the VGC SiPM outperforms the PGC
SiPM, exhibiting a true PDE of (22.5 ± 0.5) %, which is significantly
higher than the PDE of (10.9 ± 0.3) % obtained for the PGC SiPM. The
superior PDE of the VGC SiPM is attributed to a larger active or
photosensitive area due to the virtual guard rings and a thinner n-layer
in the photosensitive region.
The role of echocardiography in evaluating mechanical intravascular hemolysis after cardiac artificial prosthesis implantation: a literature review
Authors: Zhang Yuhang , Wang Jing
Published: May 2023

Mechanical intravascular hemolysis can occur after cardiac artificial
prosthesis implantation. With the development of medical technology and
the improvement of valve design, the incidence of severe mechanical
hemolysis after surgery has been significantly reduced, but it cannot be
completely avoided. At the same time, subclinical hemolysis after
surgery is common but often ignored. With the extensive development of
cardiac interventional surgery, the issue of postoperative hemolysis
deserves further attention. Ultrasound can effectively evaluate cardiac
artificial prosthesis implantation and provide imaging evidence for
predicting and diagnosing postoperative hemolysis. This article
introduces and explores the latest progress in applying echocardiography
parameters in mechanical hemolysis after cardiac artificial prosthesis
implantation.
Successful reversal of transgene silencing in Chlamydomonas reinhardtii
Authors: Beauchemin Remy , Mérindol Natacha , Fantino Elisa I. , Lavoie Pamela , Nouemssi Serge Basile , Meddeb-Mouelhi Fatma , Desgagné-Penix Isabel
Published: May 2023

Chlamydomonas reinhardtii has been successfully engineered to produce
compounds of interest following transgene integration and heterologous
protein expression. The advantages of this model include the
availability of validated tools for bioengineering, its photosynthetic
ability and its potential use as biofuel. Despite this, breakthroughs
have been hindered by its ability to silence transgene expression
through epigenetic changes. Histone deacetylases (HDAC) are main players
in gene expression. We hypothesized that transgene silencing can be
reverted with chemical treatments using HDAC inhibitors. To analyze
this, we transformed C. reinhardtii, integrating into its genome the
mVenus reporter gene under the HSP70-rbcs2 promoter. From 384
transformed clones, 88 (22.9 %) displayed mVenus positive (mVenus+)
cells upon flow-cytometry analysis. Five clones with different
fluorescence intensities were selected. The number of integrated copies
was measured by qPCR. Transgene expression levels were followed over the
growth cycle and upon SAHA treatment, using a microplate reader, flow
cytometry, RT-qPCR, and western blot analysis. First, we observed that
expression varies with the cell cycle, reaching a maximum level just
before the stationary phase in all clones. Second, we uncovered that
supplementation with HDAC inhibitors of the hydroxamate family, such as
vorinostat (suberoylanilide-hydroxamic-acid, SAHA) at the initiation of
culture increases the frequency (% of mVenus+ cells) and the level of
transgene expression per cell over the whole growth cycle, through
histone deacetylase inhibition. Thus, we propose a new tool to
successfully trigger the expression of heterologous proteins in the
green algae C. reinhardtii, overcoming its main handicap as an
expression platform.
Development of network pharmacology in sepsis treatment
Authors: chen fangling , chen maolin
Published: May 2023

So far, sepsis is still a global disease and health problem facing
mankind. Due to the complexity of the pathophysiology and pathogenesis
of sepsis, the idea that a drug corresponds to a single target - a
single disease is no longer suitable for the treatment of complex
diseases such as sepsis. The application of network pharmacology to
explore the signal network relationship between diseases, targets, and
drugs has gradually become a new disease treatment methodology. This
effective treatment for disease targets can improve the effectiveness
and success of drug therapy, and it is possible to develop from the
current treatment of symptoms of complex diseases to the real cure of
complex diseases. This paper will discuss the application and discovery
of network pharmacology in the treatment of sepsis, to provide a certain
scientific theoretical basis for the subsequent basic and clinical
research of sepsis treatment.
On-chip all-optical multicasting of mode-division multiplexing QPSK signals
Authors: Chen Baobao , Zhao Yi , Tan Haoyang , Guan Xaiowei , Gao Shiming
Published: May 2023

We propose and experimentally demonstrate an on-chip all-optical
multicasting (AOM) for 40 Gbit/s mode-division-multiplexed quadrature
phase-shift keying (MDM-QPSK) signals based on a parallel
dispersion-engineered multimode nonlinear silicon waveguide. Five
dual-mode multicast wavelengths are successfully obtained on the
generate idlers, and the power penalties of all the multicast channels
are less than 1.1 dB at the bit error rate (BER) of 3.8×10-3. The
dual-mode AOM scheme has the potential to promote the ability of optical
cross-connect in practical hybrid multiplexed networks including MDM
channels.
Manuscript title Prospective evaluation of oral levetiracetam for prophylaxis of busulfan-induced seizures in children undergoing hematopoietic stem cell transplantation
Authors: Aragão Marcelo de Melo , Zamperlini Gustavo , Seber Adriana , VG Zecchin , Lustosa Cintia Monteiro , Pinho Ricardo , Rodrigues Marcelo
Published: May 2023

Busulfan is commonly used in the conditioning regimen for hematopoietic
stem cell transplantation. Due to the risk of seizures associated with
its use, prophylaxis with an anti-seizure drug is required. We
prospectively evaluated the effectiveness of oral levetiracetam in
children and adolescents for the prevention of busulfan-induced
seizures. None of the 64 patients included in the study experienced
seizures during the conditioning therapy or side effects that required
discontinuation of the drug. Our results suggest that oral levetiracetam
is effective in this setting.
Cytoprotective effects of Nigella sativa seeds on monosodium glutamate induced seminal vesicle damages: Histological and immunohistochemical studies
Authors: Abd-Elkareem Mahmoud , Aljazzar Ahmed , Amer Ayman S. , El‑Rahman Mokhless A. M. Abd
Published: May 2023

Monosodium glutamate (MSG) is a worldwide food [flavour
enhancer](https://www.sciencedirect.com/topics/neuroscience/flavor-enhancers)
commonly used by the food industry. This feed additive may cause male
infertility. Nigella sativa seeds (NSS) is a widely used in
herbal medicine as it has many biological benefits and could provide a
solution. This work was designed to investigate the histological effects
of NSS on rats ingesting MSG. To achieve this aim, adult male albino
rats (2- 3 months old) were randomly and equally assigned into three
experimental groups. For a period of 21 days, control group received no
treatment, MSG group received MSG as 30 g/kg feed, and MSG + NSS group
received MSG as 30 g/kg feed and NSS as 30 g/kg feed. Seminal vesicle
histopathology in MSG group showed mild seminal vesiculitis with
degeneration of smooth muscle fibers in tunica muscularis. In addition,
there was an increase in the amount of connective tissue and apoptotic
cells count. Periodic Acid Schiff stain indicated irregular and
interrupted epithelial basement membranes. Glutathione reductase (GR),
superoxide dismutase 2 (SOD2), and caspase-3 immuno-expressions
increased in MSG group. It was found that there was an increase in the
number of apoptotic cells, intraepithelial lymphocytes and dendritic
cells in MSG group. However, treatment with NSS ameliorated these
disturbances. NSS mitigated MSG-induced seminal vesicle damage by its
histoprotective, cytoprotective and anti-apoptotic activities.
Proteomics Elucidating Physiological and Pathological Functions of TDP-43
Authors: Morato Jorge García , Gloeckner Christian Johannes , Kahle Philipp
Published: May 2023

Trans-activation response DNA binding protein of 43kDa (TDP-43)
regulates a great variety of cellular processes in the nucleus and
cytosol. In addition, a defined subset of neurodegenerative diseases is
characterized by nuclear depletion of TDP-43 as well as cytosolic
mislocalization and aggregation. To perform its diverse functions TDP-43
can associate with different ribonucleoprotein complexes. Combined with
transcriptomics, MS interactome studies have unveiled associations
between TDP-43 and the spliceosome machinery, polysomes and RNA
granules. Moreover, the highly dynamic, low-valency interactions
regulated by its low-complexity domain calls for innovative proximity
labeling methodologies. In addition to protein partners, the analysis of
posttranslational modifications showed that they may play a role in the
nucleocytoplasmic shuttling, RNA binding, liquid-liquid phase separation
and protein aggregation of TDP-43. Here we review the various TDP-43
ribonucleoprotein complexes characterized so far, how they contribute to
the diverse functions of TDP-43, and roles of post-translational
modifications. Further understanding of the fluid dynamic properties of
TDP-43 in ribonucleoprotein complexes, RNA granules, and self-assemblies
will advance the understanding of RNA processing in cells and perhaps
help to develop novel therapeutic approaches for TDPopathies.
Surgical waiting lists and queue management in a Brazilian tertiary public hospital
Authors: Pazin-Filho Antonio , Dallora Maria Eulália Lessa do Valle , Velasco Tonicarlo Rodrigues , Santos Roberto de Oliveira Cardoso dos , Volpe Gustavo Jardim , Moroço Diego Marques , Souza Danilo Arruda de , Canabrava Claudia Marques , Garcia Luis Vicente , Joviliano Edwaldo Edner , Maciel Benedito Carlos
Published: May 2023

Introduction: Centralized management of queues helps to reduce
the surgical waiting time in the publicly funded healthcare system, but
this is not a reality in the Brazilian Unified Healthcare System.
Objectives: To describe the implementation of the “Patients
with Surgical Indication” (PSI) in a Brazilian public tertiary
hospital; To assess the impact on waiting time and its use in rationing
oncological surgeries during the COVID-19 Pandemic. Methods:
Retrospective observational study of elective surgical requests
(2016-2022) in a Brazilian general, public, tertiary university
hospital. We recovered information regarding the inflows (indications),
outflows and their reasons, the number of patients, and waiting time in
queue. Results: We enrolled 82,844 indications in the PSI
(2016-2022). The waiting time (median and interquartile range) in days
decreased from 98(48;168) in 2016 to 14(3;152) in 2022
(p<0.01). The same occurred with the backlog that ranged from
6,884 in 2016 to 844 in 2022 (p<001). During the Pandemic,
there was a reduction in the number of non-oncological surgeries per
month (95% confidence interval) of -10.9(-18.0;-3.8) during Phase I
(January 2019-March 2020), maintenance in Phase II (April 2020-August
2021) 0.1(-10.0;10.4) and increment in Phase III (September
2021-December 2022) of 23.0(15.3;30.8). In the oncological conditions,
these numbers were 0.6(-2.1;3.3) for Phase I, an increase of
3.2(0.7;5.6) in Phase II and 3.9(1 ,4;6,4) in Phase III.
Conclusion: Implementing a centralized list of surgical
indications and developing queue management principles proved feasible,
with effective rationing. It unprecedentedly demonstrated the decrease
in the median waiting time in Brazil.
Groundwater Level Variation Analysis Using Hydrogeophysical Methods in an Area of Campo Sujo in Cerrado, Chapada dos Veadeiros Region, Goiás
Authors: Vilarinho Gustavo Xavier , Borges Welitom Rodrigues , Leão Santos Marcelo Henrique , Heringer Rodrigo Almeida , Cunha Luciano Soares , Oliveira Rafael Silva , Mendes Thiago Lima , Xavier Rafael de Oliveira , Verona Larissa da Silveira
Published: May 2023

Cerrado’s campo sujo areas have been one of the main focuses of anthropic occupation in the Chapada dos Veadeiros region, Brazil’s Central Plateau, as they are easily accessible flattened areas with less dense vegetation. They are usually associated with wetlands representing excellent water reservoirs and groundwater recharge zones. The environmental characterization and analysis of water level variation are essential to investigate the impacts of human occupation. Hydrogeophysics represents one of the main subsurface research tools due to its easy application and efficiency in identifying the water level, with emphasis on Ground-penetrating radar (GPR), and electrical resistivity tomography (ERT). An analysis of GPR sections with 200, 400, and 900 MHz frequency antennas associated with the resistivity model was carried out to identify structures, and map the groundwater level. The overlapping data compose a hydrogeophysical model with good correlation to direct measurements of water level in a monitoring well, and soil horizons mapped in a trench. The GPR proved to be efficient in mapping the water level, mainly about to the survey with a 400 MHz antenna, shown as a horizontal reflector associated with attenuation portions of the reflection signal, registering in profile the lowering of the water level from 1.68 m in May to 3.35 m in August. The resistivity model showed a good correlation with the variations between the mapped soil horizons. The analysis shows that constructing a hydrogeophysical model is an excellent alternative for identifying the water level, and characterizing the shallow subsurface by applying non-invasive techniques. The study area represents a preserved area of campo sujo, and the research data can be used for comparison with future surveys, in addition to representing a base hydrogeophysics methodology that showed promising results for the physiographic characteristics of the area, which can be replicated in regions of similar geoenvironmental aspects.
Effects of comprehensive rehabilitation on weight reduction in myocardial infarction patients
Authors: Karvetti RL Knuts LR.
Published: May 2023

The effect of a comprehensive rehabilitation programme, including diet therapy, was studied in overweight male myocardial infarction (MI) patients randomly assigned to a rehabilitation group (n = 69) and a control group (n = 64). The results show a mean weight decrease of 3.8 kg in the rehabilitation group and a mean weight increase of 1.1 kg in the control group (t = -5.78, p less than 0.001). The proportion of patients reducing their weight more than 5 kg was 33% in the rehabilitation group and 5% in the control group (chi 2 = 15.6, p less than 0.001). Patient characteristics which significantly affected the weight change by univariate analysis were age, level of overweight, smoking habits, employment situation and social problems. Multivariate analyses yielded a two-variable model with moderate explanatory power in the rehabilitation group. The model includes the variables Body Mass Index and cessation of smoking before MI.
Correlation between clinical examination and quantitative gait analysis in patients operated upon with the Gunston-Hult knee prosthesis
Authors: Olsson E , Barck A.
Published: May 2023

A group of 21 patients with total knee joint replacement was followed-up ten years after the operation. The clinical assessment including pain, range of motion, muscle strength and knee function was related to an objective gait analysis which included ground reaction force patterns and joint angular motion. This method of gait analysis not only confirmed in an objective way the impression from the clinical assessment but also provided a more accurate gradation of the results. The method is applicable to patients with weight bearing problems.
Measurement of skin mobility in the upper back
Authors: Hirschberg GG , Fatt I , Brown RD.
Published: May 2023

On manual testing for skinfold tenderness greater resistance has been reported in patients with marked skinfold tenderness. On objective measurement of skin mobility, by raising a skinfold with a vacuum pump and by establishing a stress/strain curve, no difference in skin mobility was found between subjects with and without skinfold tenderness. Furthermore, contrary to manual testing, the suction testing causes no pain in subjects with clinical skinfold tenderness. In a second series of suction tests, comparing skin mobility in a subject with relaxed and contracted underlying muscles, it was found that muscular contraction reduces skin mobility by 50%. The conclusion is that resistance felt by manual skinfold testing is not inherent in the structures, but is caused by contraction of underlying muscles because of pain caused by the manual skinfold test.
Radiographic verification of knee goniometry
Authors: Enwemeka CS.
Published: May 2023

The accuracy of knee goniometry was examined by comparing goniometric measurements with radiographic bone angle measurements of six positions of the knee, namely, 0 degree, 15 degrees, 30 degrees, 45 degrees, 60 degrees, and 90 degrees. Within the first 15 degrees of knee flexion joint excursion measured by goniometry differed significantly from bone angle measurement (p less than 0. 01). With 30 degrees of knee flexion or more, no significant difference was found between goniometric measurements and bone angle measurements of knee motion. These findings suggest that within the first 15 degrees of knee flexion, goniometric measurement of joint excursion may be remarkably wrong. On account of this, it was suggested that when range of motion is limited at the knee joint, caution should be exercised in determining movement gains or losses within the initial 15 degrees of knee flexion.
Low power Ga-Al-As laser treatment of painful osteoarthritis of the knee. A double-blind placebo-controlled study.
Authors: Bülow PM , Jensen H , Danneskiold-Samsøe B
Published: May 2023

The aim of this double-blind study was to evaluate the effect of low power Ga-Al-As laser treatment on chronic pain related to osteoarthritis of the knee with periarticular tender points. Twenty-nine out-patients with uni- or bilateral osteoarthritis of the knee were included and randomly assigned to treatment with either laser or placebo laser. Fourteen patients received active laser treatment and all patients included completed the study. The effect variables were daily levels of pain, analgesic requirements, palpation tenderness and isokinetic quadriceps strength. Each patient participated in the study for 9 weeks and registered daily level of pain and consumption of analgesics. In weeks 4, 5 and 6 the patients received a total of nine treatments, each of 15 min and administered to periarticular tender points. The dose per treatment was 22.5 joule. No significant differences in any of the effect variables were found between the two groups before, during or after treatment. With regard to the patients' overall assessment there was a clearly demonstrable positive effect of treatment in both groups. This is likely to be due to a placebo effect.
Connection between smoking and back pain--findings from an Icelandic general population study
Authors: Líndal E , Stefánsson JG
Published: May 2023

The association between pain in general, back pain and smoking was studied in a sample of subjects from the general public (n = 862). The results show that smoking men had pain problems more frequently than women (p < 0.0001). In comparison with non-smokers, smokers were found to have back pains more frequently (p < 0.01). Male smokers were also found to have a higher frequency of intervertebral disc problems than female smokers (p < 0.009). The frequency of disc problems encountered by the smoking subjects indicates a possible connection between smoking and back pain.
Validity of five common manual neck pain provoking tests
Authors: Sandmark H , Nisell R
Published: May 2023

The purpose of the present study was to assess five manual tests for pain provocation of the neck to determine their suitability for epidemiological investigations. To 75 randomly selected men, five manual pain-provoking tests were applied in a single-blind design. Prevalence of reported neck dysfunction, sensitivity, specificity, and positive and negative predicted value for each test were calculated. 22 of the 75 reported present neck pain, while the remainder reported freedom from neck pain for at least one year. Palpation over the facet joints in the cervical spine was found to be the most appropriate screening test to corroborate the replies in self-reported questionnaires on dysfunctions of the neck. The outcome of this test was quite consistent with the reported neck pain. The test of the formina intervertebralia and the upper limb tension test caused pain in almost all subjects with reported neck dysfunctions, though not causing referred pain in the arm as an indication of neurogenous tissue origin, as it was aimed to. Neither the neck rotation test nor the active flexion/extension test was sufficiently provocative to confirm the reported neck pain in these subjects, as both were insufficiently sensitive.
Clinical Findings and Return to Work After Heart Valve Replacement
Authors: Pere E , Saraste M , Inberg M , Arstila M , Vuori I , Kallio V
Published: May 2023

One hundred and thirteen patients operated during the years 1971 to 1976, were re-examined at an average of 26. 3 months after heart valve replacement. The functional capacity assessed by the NYHA-classification improved in about 40% of the patients. About 80% considered their symptoms and well-being to have improved after the operation. At the re-examination, heart size was most often enlarged in patients with mitral valve replacement. The average work load measured in bicycle ergometer test was higher in patients with aortic valve replacement compared to those with mitral valve replacement. Patients with aortic valve replacements were working more often (54%) than those with mitral valve replacements (37%). The mean age of patients who were working was significantly lower than in patients who were retired. There was a statistically significant relation between the physical working capacity and the working status. The employability assessed by history and clinical findings corresponded well to the actual work situation in individual patients.
Shoulder externally rotating exercises with pulley apparatus. Joint load and EMG
Authors: Harms-Ringdahl K , Arborelius UP , Ekholm J , Németh G , Schüldt K
Published: May 2023

The mechanical load on the gleno-humeral joint and the muscular activity during shoulder external rotation resisted by a pulley apparatus were analysed using normalized, low-pass-filtered EMG recorded from the infraspinatus, deltoid, pectoralis major and trapezius muscles. The load moment about the longitudinal axis of the joint was compared with the distribution of maximum muscle moment over different angles throughout the range of motion. The effect of subject positioning on the joint load and the muscular activity was studied. The best adaptation between the curves for load moment and maximum muscle moment was obtained when the subject was positioned sitting with the pulley located 20 degrees posterior to a frontal plane through the shoulders at a distance of 1. 3 m from the joint. Of the four muscles investigated, the infraspinatus was the most active. The method described might be used to find optimal designs of shoulder external rotation exercises with special regard to avoiding unintentional overloading of joint structures weakened by disease or trauma.
Simulation of Paretic Gait in Normal Subjects by Loading the Ankles
Authors: Eke-Okoro ST , Larsson LE , Sandlund B
Published: May 2023

Normal subjects were loaded with increasing weights (2-6 kg) applied around the ankles. During these conditions stride length increased in relation to velocity. The percentage duration of single support in relation to stride duration increased. Provided the same load was applied around both ankles increase was symmetrical. Consequently there was also an increase of swing as well as a decrease of stance and of double support. The results contrast in all respects to what was found in previous experiments when the load was carried in the hand. During these conditions stride length decreased as well as the duration of single support. The two experimental conditions differed in that with ankle loading the swing phase was loaded while in the other case stance was loaded. The two types of experiment may help to explain why some patients with paretic legs walk with short strides, while others walk with strides that are normal or slightly prolonged.
Issues in the Management of Behaviour Disturbance as a Consequence of Severe Head Injury
Authors: Tate RL
Published: May 2023

The management of organic psychosocial deficit following severe head injury has been a neglected area of rehabilitation. Behavioural modification programmes are being utilised increasingly to ameliorate inappropriate behaviours within the rehabilitation framework. Patterns of organic psychosocial deficits in the head injured are described and issues in the management of behaviour disturbances and the constraints that operate in the application of psychological techniques to the population who suffer acquired brain damage are discussed.
Relative Mechanical Load on Shoulder and Elbow Muscles in Standing Position When Handling Materials Manually. A Study of Packing Work
Authors: Svensson OK , Arborelius UP , Ekholm J
Published: May 2023

When a patient with a musculoskeletal disorder returns to work after rehabilitation, the work-station should be designed so that the impaired muscle groups are less exposed to load. The work posture desirable for a particular muscle group might impose higher load on another muscle group. Since the shoulder muscles usually are stronger than the elbow muscles, a direct comparison of the loads is difficult. To make comparisons possible, the load moment about the investigated joints were divided by the counteracting maximum muscular moments, and a Muscular strength Utilization Ratio (MUR) was obtained. Using this principle, the muscular load on the shoulder and elbow was investigated in 72 different packing work postures. Different combinations of box size, box angle, edge height and weight of object handled were studied. There was a higher relative load on the shoulder than on the elbow. The concept of relating joint load to strength may serve as a guideline for how high a patient's strength should be before returning to work to avoid further injuries.
Changes in Histochemical Profile of Muscle After Long-Term Electrical Stimulation in Patients With Idiopathic Scoliosis
Authors: Grimby G , Nordwall A , Hultén B , Henriksson KG
Published: May 2023

Adolescent patients with idiopathic scoliosis were treated with long-term electrical stimulation (30 Hz) at the posterior axillary line on the convex side of the curvature in order to correct the spinal deformity. The patients were also followed with muscle biopsies from the latissimus dorsi of the stimulated side taken before, after 3 and 6 months of electrical stimulation. There was a tendency for an increase in the percentage of type I and especially the type II C (undifferentiated) fibers after stimulation. The mean muscle fiber area and the fiber areas of the various fiber types did not change significantly. Histopathological findings were generally rare before as well as after 3 months of electrical stimulation, the only noticeable finding being a somewhat increased frequency of atrophic fibers in groups after 6 months of stimulation. In all studied patients the enzymatic activity of citrate synthase increased after 3 months and further in three studied patients after 6 months of stimulation. The present study gives some evidence of an adaptive process caused by electrical stimulation towards a more fatigue-resistant muscle.
Isometric Muscle Force and Anthropometric Values in Normal Children Aged Between 3.5 and 15 Years
Authors: Bäckman E , Odenrick P , G Henriksson K , Ledin T
Published: May 2023

Isometric muscle force was measured in 217 normal children aged 3.5-15 years. The standard error of a single determination made by the same observer was ca. 9% of the muscle force. When two measurements were made by different observers the standard error of the difference was estimated at ca. 17%. Reference values for isometric force are given for boys and girls separately. With regard to 7 of the 10 muscle groups tested the force was significantly greater in boys than in girls as early as at ca. 10 years of age. Age and weight were the most important predictors of muscle force.
Effect of pulsed ultrasound versus placebo on muscle soreness perception and muscular performance
Authors: Hasson S , Mundorf R , Barnes W , Williams J , Fujii M
Published: May 2023

The purpose of this study was to compare the analgesic effect of pulsating ultrasound treatment and placebo on delayed onset of muscle soreness produced by an eccentric exercise bout. In addition, the effect of pulsed ultrasound on muscular performance following an eccentric exercise bout was studied. Eighteen untrained subjects were randomly assigned to: 1) ultrasound (A) [N = 6] over the areas of concentrated muscle soreness, i.e. proximal vastus lateralis and distal vastus medialis; 2) placebo ultrasound (B) [N = 6]; and 3) no therapeutic intervention (C) [N = 6]. Baseline data were recorded for maximum isometric knee extension contraction (MVC), maximum knee extension torque (MT), knee extension work (W), and soreness perception (SP). All values were subsequently reassessed 24 and 48 hours after intense muscular activity. Immediately following the 24 hour reassessment the A group received ultrasound treatment, the B group received placebo ultrasound, while the C group received no treatment. Percent deviation from baseline of SP, MVC, MT and W were significantly less for A than B and C (p less than 0.05) at 48 hours post muscle soreness bout. These data indicate that pulsed ultrasound accelerates restoration of normal muscle performance, and thus is effective in decreasing delayed onset of muscle soreness. The mechanism for decreasing soreness perception in the muscle is unknown, but may be related to decreasing intramuscular pressure and/or decreasing the inflammatory response.