bluuebunny/crossref_metadata_2025 huggingface dataset:
Detection and classification of cervical cancer images using CEENET deep learning approach
Authors: Subarna T.G. , Sukumar P.
Published: April 2022

Earlier detection of cervical cancer in women can save their lives before a chronic development. The accurate detection in cancer tissues of cervix in the human body is very important. In this article, cervical images were classified into either affected or healthy images using deep learning architecture. The proposed approach was designed with the modules of Edge detector, complex wavelet transform, feature derivation and Convolutional Neural Networks (CNN) architecture with segmentation. The edge pixels in the source cervical image were detected using Kirsch’s edge detector, the Complex Wavelet Transform (CWT) was there used to decompose the edge detected cervical images into number of sub bands. Local Derivative Pattern (LDP) and statistical features were computed from the decomposed sub bands and feature map was constructed using the computed features. The featured map along with the source cervical image was fed into the Cervical Ensemble Network (CEENET) model for classifying of cervical images into the classes healthy or cancer (affected).
National trends in the incidence and management of retinopathy of prematurity in the United States, 2009 –2018
Authors: Cudjoe G.A. , Ameley A. , Ohemeng-Dapaah J. , Bhatt P. , Donda K. , Dapaah-Siakwan F.
Published: April 2022

BACKGROUND: Retinopathy of prematurity is a major cause of morbidity in preterm infants but population-based studies to evaluate recent trends in incidence in the United States (US) are lacking. Moreover, previous studies did not include the use of anti-Vascular Endothelial Growth Factor medications. The objective was to examine the recent secular trends in the incidence and treatment of severe retinopathy of prematurity (sROP) in the United States (US) from 2009 to 2018. METHODS: This was a population-based, serial cross-sectional study that utilized data from the National Inpatient Sample. The inclusion criteria were preterm infants with gestational age (GA) ≤30 weeks and length of stay > 28 days. The primary outcomes were trends in ROP surgery (photocoagulation, cryotherapy, scleral buckling, vitrectomy) and intravitreal injection of therapeutic (anti-VEGF) medications. The Cochrane-Armitage test was used to evaluate trends and P-value < 0.05 was considered significant. RESULTS: Out of 279,664 hospitalizations that met the inclusion criteria, 12,942 (4.6%) had sROP. Those with sROP were more likely to have severe intraventricular hemorrhage (12.5% vs 6.1%), bronchopulmonary dysplasia (48.2% vs 25.9%), and pulmonary hypertension (10.7% vs 4.7%). From 2009–2018, sROP significantly increased from 3.4% to 5.3% (P < 0.001), ROP surgery decreased from 36.8% to 11.9% (P < 0.001) while intra-vitreal administration of therapeutic drugs increased from 2% to 7.6% (P < 0.001). CONCLUSION: Surgery for sROP decreased while intra-vitreal administration of therapeutic drugs increased in the setting of increasing incidence of sROP in the US. Taken together, these findings suggest a gradual practice change and the long-term outcomes of intra-vitreal agents warrants future study.
Pre-Muhammadan Prophets in the Muslim Tradition and Piety
Authors: Mohamed Meerasahibu Dheen Mohamed
Published: April 2022

The belief in prophets before the Prophet Muhammad (SAW) and in the divine books that Allah Almighty sent to humanity/books revealed to the humanity by Allah Almighty constitute two of the six/five articles of faith in Islam. The denial of any one of them would result in “apostasy” and excommunication. All textbooks on the Islamic creed as well as all other major theological sources acknowledge these beliefs which also comprise a primary component of the curriculum taught to Muslim children. However, the impact of these beliefs in Islamic thought and practice needs to be explored extensively.
This paper attempts to highlight the role played by the previous prophets in Islamic life, especially in its devotional practices, with the hope that this type of study will contribute to/aim of increasing the awareness of other religions and developing a more inclusive approach towards them in the spirit of mutual appreciation and respect. These are –undoubtedly – some of/among the more pertinent and noble objectives that concern the modern man and the society.
The paper begins by explaining the importance of belief in the previous prophets as set in the sources of Islam and then proceeds to highlight some aspects of its practical importance in Islamic thought and life. It concludes with a special focus on some Sufi concepts and practices that display their intrinsic connections to previous prophets.
A Stereotypical Approach towards Muslim and Islam in Australian Press: Framing Analysis of Daily Telegraph and Daily Courier Mail
Authors: Haseeb-ur-Rehman Warrich  , Jamal ud Din  , Khan Rooh ul Amin
Published: April 2022

Framing of the Muslims and Islam has been a debatable/is a contentious area of interest for researchers. This study is designed to analyze the approach of the Australian press towards the Muslims and Islam when it covers the terrorist incidents in Australia and in other part of the world, especially in the western countries. The news related to terrorist incidents and activities published during a six-month timeframe, that is, from October 2016 to March 2017, in two popular newspapers namely The Daily Telegraph (leaning towards the Liberal Party) and The Courier Mail (right-centered newspaper in its nature) was thoroughly analyzed. The major objective was to know how these newspapers frame the Muslims and Islam in their news contents when the issue of terrorism is under discussion. Despite the different political leanings of the selected newspapers, their approach towards the Muslims and Islam was found to be similar as both the dailies framed the terrorism related stories in a way to associate the Muslims and Islam with terrorism.
Social Change in the Time of Covid-19: A Phenomenal Study in Malaysia from the Perspective of Maqasid Al-Sharī‘ah
Authors: Harun Muhammad Safwan , Md. Ariffin Mohd Farhan , Muhammad Ikhlas Rosele
Published: April 2022

The COVID-19 pandemic has made a huge impact on Malaysia since the first Movement Control Order (MCO) was implemented in March 2020. All sectors including the economic sector, tourism, services, sports, the religious sector and entertainment have been subjected to the Standard Operating Procedures (SOPs), such as the wearing of face masks, hygienic care and physical distancing. Although compliance with the SOPs can still be questioned, it is undeniable that it has changed the society’s way of living in Malaysia as the people are urged to adopt and adapt to the new norms in order to combat the spread of the virus. In fact, social change in times of COVID-19 can be considered as a new ‘urf (custom) practiced by the whole Islamic world. The issue is that these new changes coming with the application of the various SOPs for virus prevention are claimed to be for the benefit of religion, health, economy and education. Through phenomenal methodologies/Using a phenomenological methodology, this study emphasizes two main objectives, that are, explaining social change due to COVID-19 in Malaysia and analysing the correlation between social change and the parameters of maqāsid al-sharī‘ah (the higher purposes of Shari’ah) in each new practice. In conclusion, it should be emphasized that the current social change must correspond with maqasid al-shari’ah especially in dealing with the matters of the religion.
Vincent le Blanc as the Second Non-Muslim in Makkah and Madinah
Authors: Spahic Omer
Published: April 2022

Societies and nations generally construct their worldviews and strive to realize their religious and political objectives in the light of these worldviews. Christians of Europe in the 16th and 17th centuries began to explore the world and discovered new continents. They disseminated their views related to the peoples of the world, especially the Muslims, through their travelogues and books. It is generally acknowledged that the books published from the national pedestal are always biased. Hence, the analysis of books that are politically and religiously oriented is a very important task. Keeping this purpose in view, this article discusses the case of Vincent le Blanc as the second European non-Muslim to visit Makkah and Madinah. It argues that, in reality, the man never did as he claimed. The visit was staged mainly for the interest of Christian anti-Islamic polemics. The justification of this contention is two-pronged. Le Blanc’s fallacious, self-contradictory and irrational accounts of Makkah and Madinah, their holy mosques, and of hajj rituals are scrutinized. It is followed by bringing to fore his extensive plagiarism of the work of Ludovico di Varthema. The findings of this study suggest that the books written by tourists such as Le Blanc are characterised by biases and alienated approaches. Therefore, their propositional as well as linguistic material should always be viewed cautiously to safeguard against their misleading contents.
The Creation of Moon: Comparative Analysis between Modern Sciences and Religious Studies
Authors: Qari Abdul Basit  , Hafiz Abdul Rashid  , Awais Bin Zahid  , Muhammad Ayub
Published: April 2022

Curiosity is among the pre-eminent traits of human beings that differentiates them from other species. The majority of human beings believe in a religion that provides them with standards to be followed in this world and knowledge about the hereafter. Holy scriptures as a source of guidance also provide profound knowledge about the universe, its beginning and end, its solar and lunar systems, orbits and functions and other aspects. Modern science and its discoveries sometimes contradict the premises mentioned in religious theology, which need a rational outlook acceptable to the people with a scientific approach along with a theological perspective. In Islamic cosmological perspective, it is believed that Allah Almighty made two stars in the early days for the planet earth. The moon was also a shining star emitting light from the day first. It was a source of light by itself, not merely reflecting the light of the sun. In parallel to these divine theories, various scientific theories also explain the creation of the moon. Prominent among these are the Giant Impactor, Co-Accretion, and the Capture theory. The present research fills the knowledge gap and provides concrete and rationalized information regarding the creation of the moon in religion and modern science.
Use of Diperoxocholric Acid in Infected Diabetic Foot Ulcers Leading to Osteomyelitis: Case Reports
Authors: K V N N Santosh Murthy  , Katke Vaishali , Kiran Mayuresh
Published: April 2022

This article describes three patients who had an episode of infected diabetic foot ulcer with osteomyelitis, and subsequently treated with a Diperoxochloric acid topical solution. Diperoxochloric acid is a new chemical entity approved in the treatment of diabetic foot ulcer. It has properties to heal the wound and kill the microbes in wound, which is the need of hour. As most of the products that are available in market have either antimicrobial activity or wound growth factors, which have no action on microbes makes Diperoxochloric acid mechanism unique. All three ulcers showed positive wound contraction and reduction in size throughout the follow-up period ranging from 3 to 10 weeks. All the three patients showed positive signs of wound healing. One of the patients in whom amputation of great toe was advised also healed completely without any need of amputation.

Keywords: Diabetic foot ulcer, Diperoxochloric acid
Pentylenetetrazole Induced Kindling Model of Refractory Epilepsy: A Proof-of-concept Study to Explore Dose and Time Range of Phenobarbital in Rats
Authors:   Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India., Thapliyal Surabhi , Garg Nitika ,   Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India., Joshi Rupa ,   Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India., Chakrabarti Amitava ,   Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India., Medhi Bikash ,   Department of Pharmacology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Published: April 2022

Introduction: Drug-resistant epilepsy is an unmet medical condition that impacts 30% of epileptic patients. Numerous antiseizure drugs have already been developed but they provide only symptomatic relief and do not target the underlying pathogenesis. Preclinical models provide opportunities to gain insights into obscure mechanisms of drug-resistant epilepsy. Current animal models possess lacunae that need rectification and validation to discover novel antiepileptic drugs. The present study aims to validate 3 different doses of phenobarbital at 2 different periods. Methods: Pentylenetetrazole was given at a sub-convulsive dose (30 mg/kg/day/intraperitoneal [IP]) for 28 days to develop kindling in male Wistar rats. Further, kindled rats were divided into the following four groups: Pentylenetetrazole control, pentylenetetrazole and phenobarbital (20 mg/kg), pentylenetetrazole and phenobarbital 40 mg/kg, and pentylenetetrazole and phenobarbital (60 mg/kg). They were assessed on days 14 and 28 post-kindling. Seizure scoring, oxidative stress, phenobarbital plasma levels, and histopathology of hippocampal neurons were analyzed. Results: The results showed that the combination of pentylenetetrazole and phenobarbital (40 and 60 mg/kg) remarkably decreased seizure score, elucidated higher antioxidant effect, and prevented neuronal injury on day 14, whereas increased seizure score, oxidative stress, and neuronal death was observed with chronic administration of pentylenetetrazole and phenobarbital in kindled rats at day 28. Moreover, phenobarbital levels in blood were significantly increased at day 28 of phenobarbital treatment compared to day 14. Conclusion: The adapted protocol with phenobarbital 40 mg/kg dose could be of great potential in screening antiseizure drugs in refractory epilepsy.
Flexible Approximation Functions for Broadband Matching
Authors: Filippovich G. A. , Yantsevich M. A.
Published: April 2022

Introduction. Intensive use of broadband signals in RF devices for various purposes is associated with the need to develop broadband elements of RF systems. Iterative methods for designing such elements are frequently uninformative and ineffective, while analytical methods give solutions only for simple models. The problem is the small set of classical approximations, which impedes dealing with complex models of elements.Aim. Development of a wide-band matching technique based on generalized Darlington synthesis using flexible approximating functions (AF) for load models with zeros of transmission at infinity.Materials and methods. The paper is based on the generalized Darlington synthesis method. To extend the capabilities of the method, approximating functions with increased variation properties are used. In order to use the results in engineering practice, a synthesis algorithm was developed, which includes three stages: formation of the frequency response, control of analyticity of the used functions and limits of matching. The method is analytical and does not use iterative procedures. The mathematical apparatus of the method is based on the analysis of residues in the zeros of transfer function of load resistance.Results. Flexible approximating functions proved to be an effective tool for designing matching circuits with multiple transfer zeros in infinity. Variative properties of the function facilitate the realization of both smooth and wave frequency characteristics. A combination of both is also possible, ensuring the best properties of both. The proposed approximating functions allow a smooth change in the frequency response, while preserving the normalization characteristic of classical approximations. Application of such functions allowed us to virtually remove the limitations inherent in the classical AF on the minimum values of the load capacitance and more than 30 % of the limiting values of inductance in the above examples.Conclusion. The developed methodology makes the process of wideband matching physically transparent and can be applied to other classes of loads.
Analysis of Financing in Education Sector and Human Development Index in Regencies/City
Authors: Hermawan Rio , Arham Muhammad Amir , Dai Sri Indriyani
Published: April 2022

The research aims to analyze the effect of financing in education sector by utilizing data from statistics of Gorontalo Province from 2015 to 2019 in five regencies and one city administration in Gorontalo Province. Therefore, the proper analysis tool to use is panel data regression and fixed effect model (FEM). The result of analysis shows that there is a positive and significant effect of financing in education sector on the human Development Index as an increase in the financing will lead to an increase in the Human Development Index too. In addition, the control variable used is Gross Participation Rate (APK) for senior High School owns a negative and insignificant effect on the human development Index. In the meantime, the Net participation Rate (APM) for senior High School owns a positive and significant effect on the increase of Human Development Index. Additionally, the use of education budget requires to be increased whether in measurable planning process distribution or productive spending. Therefore, it is indispensable to perform sustainable monitoring and evaluation from all stakeholders.
La (no) deserción escolar. Análisis de estudiantes de 9.° grado
en Colombia
Authors: Aravena Domich Marcela , Pérez Campillo Carmen Cecilia
Published: April 2022

Este es un estudio de caso con estudiantes de 9.° grado de la Institución Educativa Madre Laura, del municipio de Tierra Alta, departamento de Córdoba, en Colombia. Tuvo como objetivo comprender la (no) deserción escolar en adolescentes próximos a egresar del sistema educativo secundario. Los y las jóvenes se encuentran en una situación sociocultural vulnerable en la que inciden factores psicosociales, económicos, familiares y académicos. Se propuso una metodología mixta cualitativa y cuantitativa, con enfoque descriptivo y analítico. Es importante poder caracterizar a y comprender la situación de estos adolescentes, que quieren completar su escolaridad pese a que podrían dejarla. Los principales hallazgos permiten reflexionar desde la institución educativa, el modelo pedagógico y el personal docente sobre una participación más activa, el rol de la familia y las motivaciones de los estudiantes.
Tool, indijska filozofija i Jung
Authors: Ivanović Blanka
Published: April 2022

Tool je heavy metal-bend čiji su tekstovi pjesama ispunjeni
referencama na filozofiju, osobito na indijsku filozofiju i jungijansku
psihoanalizu. Osvrću se primarno na svjesnost i transcendenciju kako
bi proširili vlastite poglede na svijet. Konceptom sjene pak upućuju na
Jungove poglede o mračnim dijelovima sebstva koje treba konfrontirati
također u svrhu razvoja i promjene perspektive. Tekstovi njihovih pjesama
upućuju na potrebu za rastom, ali i za društvenom osviještenošću – kako
fenomenološkom, tako i socijalnom. Osvrću se i na razmišljanja o životu,
interpersonalne odnose te socijalne utjecaje. Cijeli opus Toola tako je prožet
referencama i otvoren interpretaciji, potičući svakoga na razmišljanje te
vlastito propitkivanje koncepata na koje se osvrću.
A gaita gallega tocada polo gaiteiro, ou sea carta de Cristus para ir deprendendo a ler, escribir e falar ben a lengua gallega e ainda mais
Authors: Pintos Xoán Manuel
Published: April 2022

A Real Academia Galega enceta hoxe a publicación dalgúns textos literarios que son constituíntes básicos do noso corpo cultural. E faino en reproducións facsimilares das primeiras edicións. Serán libros doadamente accesibles. Dese xeito, cadaquén poderá dispor dunha colección ilustrativa do esforzo dos nosos devanceiros. O esforzo que levaron acabo para soerguer a lingua ás fecundas outuras da vida do espírito. Iniciamos a nosa xeira coa obra de Xoan Manuel Pintos, A gaita gallega. A figura de Xoan Manuel Pintos e o alcance deste seu libro están xa ben estudados polos especialistas que disto se teñen ocupado. Aquí soamente cómpre subliñar, unha vez máis, o carácter reivindicativo de Galicia e da sua lingua que nas páxinas do escritor pontevedrés latexa con forza propia. A presente edición é unha reprodución facsimilar desta primeira edición, conmemorativa do 75 aniversario da fundación da Real Academia Galega.
ANALYSIS OF THE DATA OBTAINED DURING THE EXPERIMENT, ASSESSMENT OF OBJECTIVE SYMPTOMS TO IDENTIFY CHRONIC VISUAL FATIGUE
Authors: Horoshko V. I. , Horoshko A.
Published: April 2022

There is a growing need to prevent visual fatigue of personal computer users due to the widespreaduse of computer technology. The purpose of the work is the analysis and development on the basisof the created software and hardware complex of the optimal mode of operation and removal of fatigue,conducting a series of experiments to test the effectiveness of the proposed mode of work and rest.Conclusions: The use of microcontroller technology with a wireless interface greatly simplifiesthe component base of the developed composite electronic components and expands the possibilitiesof diagnosing human fatigue. The proposed software makes this procedure accessible and easy formost diagnostic operators in the world.
La relación de la gestión de las cadenas de suministro con los procesos de producción para la competitividad de la pyme de Aguascalientes. Aguilera
Authors: Aguilera Enríquez Luis , Hernández Castorena Octavio , López Torres Gabriela Citlali
Published: April 2022

Con el presente trabajo de investigación, aplicado a la pequeña y mediana empresa (pyme) del sector de manufactura se pretende explicar si existe una relación positiva entre la gestión de la cadena de suministro y los procesos de producción, con la finalidad de que sean más competitivas; para ello se aplicó un instrumento de evaluación dirigido a los gerentes, donde los resultados obtenidos se han analizado con apoyo del paquete estadístico eqs, donde a través de ecuaciones estructurales se ha dado respuesta al objetivo planteado. En este sentido se puede concluir que la gestión de las cadenas de suministro tiene una relación positiva con los procesos de producción, y a su vez esta relación muestra un impacto positivo en la competitividad de la pyme de Aguascalientes. Para esta investigación se ha utilizando una muestra de 120 empresas, las cuales contienen de cinco a 250 trabajadores.
En busca de un posicionamiento de mercado: Modelo de Mercadotecnia
Authors: Montero Delgado Nancy Imelda , Muñoz Zapata Daniel , Vázquez Núñez Sergio Octavio
Published: April 2022

Esta investigación nace con la finalidad de identificar las variables que inciden en el diseño efectivo de una estrategia de mercadotecnia, de tal forma que el empresario implemente acciones que lo lleven a mejorar la posición en el mercado y su reflejo en el nivel de ventas. Para esto, se observan los modelos que han intentado explicar la efectividad de la mercadotecnia en el tiempo; partiendo así del modelo de Kotler (1977) y se integran los hallazgos identificados en otros modelos, así como la inserción de una variable adicional que pretende explicar con mayor claridad el nivel de mercadotecnia que emplea la empresa. Como resultado se propone un modelo aplicable a la mipyme a través del cual el empresario identifica en forma clara y sencilla el nivel de mercadotecnia con el que trabaja y su efectividad
KNOWLEDGE MANAGEMENT IN THE HUMAN CAPITAL DEVELOPMENT SYSTEM AT THE LABOR MARKET
Authors:   Ivan Franko National University of Lviv, Klepanchuk Olha
Published: April 2022

The relevance of the study of the impact of knowledge management and human capital development at the labor market on economic growth is determined by the need to overcome imbalances in the socio-economic development of Ukraine. The article is dedicated to the identification of the main features of human capital development, to the assessment of its level in Ukraine, as well as to the factors identifying the impact of knowledge management and human capital development on economic growth. The development of human capital is considered to be the most important prerequisite for ensuring sustainable economic growth in Ukraine. The main features of the development of human capital as a resource for increasing productivity and, consequently, the growth of capitalization at the micro, meso and macro levels is the accumulated stock of production competencies and inseparable knowledge and abilities. The correlation of the quality of knowledge flow management and GDP is revealed, the density of which reflects the desire of highly developed markets to attract investment in human resources development and the formation of demand for new knowledge. The high level of human capital accumulation in Ukraine is confirmed by the analysis of the range of international rankings, including 32nd place in the Global Innovation Index 2020 with the rate of 37,7% for knowledge-intensive employment. It is noted that to ensure economic growth it is necessary to apply the knowledge gained by citizens in the labor market. It is proposed to assess the effectiveness of knowledge management in the system of human resources development in the labor market by measuring its contribution to the economic growth of the regions of Ukraine. It is recommended to choose the growth rates of production, labor productivity, and the elasticity of employment growth as targets. It was found that the growth of human capital has an impact on productivity growth and the elasticity of employment growth. As human capital grows, the elasticity of employment growth will decrease, which makes the economy of the regions less labor-intensive and leads to greater economic growth. The simulation allowed us to identify the main factors of the direct and indirect impact of human capital development on the level of economic growth. In the future, it is proposed to study the models of human capital development under crisis conditions and to develop strategic guidelines for knowledge management at the institutional level.
Pengujian Validitas dan Reliabilitas System Usability Scale (SUS) Untuk Perangkat Smartphone
Authors: Usman Muhammad Lulu Latif , Gustalika Muhamad Azrino
Published: April 2022

Untuk mengukur suatu perangkat lunak lebih spesifik berbasis telepon seluler smartphone dapat diterima oleh pengguna maka dilakukan pengujian Usability.  Untuk membuat quisioner yang dapat digunakan untuk melakukan pengujian System Usability Scale (SUS) yang dinyatakan valid dan reliabel. Quisioner diuji menggunakan Expert Review dan Product-Moment Coefficient untuk uji validitas, serta Cronbach Alfa untuk uji reliabilitas. Berdasarkan hasil uji yang dilakukan didapatkan 10 butir quisioner untuk uji SUS dengan seluruh butir dinyatakan valid secara Expert Review dan Product-Moment Coefficient, serta reliabel dengan skor Cronbach Alfa 0,778086452. Terdapat beberapa penelitian terkait pembuatan quisioner untuk uji SUS dimana bahasa yang digunakan bahasa indonesia dan bahasa inggris dengan jumlah pertanyaan sebanyak 10 butir. Penelitian ini sendiri memberikan opsi lain quisioner dengan mengadopsi penelitian yang sudah dilakukan dengan melakukan pengujian validitas dan realibilitas untuk menguji suatu perangkat lunak menggunakan uji SUS.
FORMULASI SEDIAAN KUMUR EKSTRAK ETANOL 96% DAUN SELEDRI (Apium graveolens L.) SEBAGAI ANTIBAKTERI Streptococcus mutans Penyebab Bau Mulut
Authors: Yasir Angga Saputra , Rai Saputri Gusti Ayu , Chandra Yudhi
Published: April 2022

Sediaan kumur telah banyak digunakan sebagai salah satu cara untuk menjaga kesehatan rongga mulut dengan cara menghambat pertumbuhan bakteri. Salah satu tanaman yang memilki daya anti bakteri adalah daun seledri (Apium graveolens L.). Tujuan penelitian ini untuk mengetahui efektivitas daun seledri dalam sediaan kumur untuk menghambat bakteri Streptococcus mutans. Ekstraksi daun seledri menggunkan metode maserasi dengan pelarut etanol 96%. Hasil Uji Fitokimia menunjukan bahwa ekstrak daun seledri mengandung alkoloid, flavonoid, tanin, saponin. Pengujian daya hambat bakteri dilakukan dengan menggunakan metode semuran. Penelitian ini menggunakan beberapa konsentrasi daun seledri yaitu 0,1%, 0,2%, 0,3% dan kontrol positif dengan hasil dapat menghambat bakteri Streptococcus mutans dengan rata-rata zona hambat berturut-turut 7,37 mm, 7,7 mm, 8,087 mm dan kontrol positif 8,26 mm. Hasil uji iritasi sediaan kumur daun seledri pada kelinci ini menunjukan tidak adanya iritasi dengan skor pembentukan eritema 0 dan skor pembentukan udema 0. Hal ini dapat disebabkan karena pH sediaan yang telah memenuhi persyaratan dan tidak adanya eksipien yang dapat memicu iritasi
ANALISIS SGOT DAN SGPT PADA TIKUS JANTAN YANG DI INDUKSI PARASETAMOL UNTUK MENETAPKAN AKTIVITAS EKSTRAK BUAH DELIMA (Punica granatum L.) SEBAGAI HEPATOPROTEKTIF
Authors: Nofita Nofita , Ulfa Ade Maria , Muslim Davit Muhamad
Published: April 2022

Enzim SGOT dan SGPT berhubungan dengan sel parenkim hati yang dikeluarkan akibat kerusakan sel hati. Pengaruh Punica granatum pada enzim hati dapat dirujuk ke pada efektivitas antioksidan yang kuat dari senyawa aktifnya yang dapat berinteraksi dengan radikal bebas. Penelitian ini bertujuan untuk menyelidiki kemungkinan aktivitas hepatoprotektif ekstrak buah delima terhadap hepatotoksisitas yang diinduksi parasetamol. Hepatotoksisitas diinduksi pada tikus jantan Sprague Dawley dengan pemberian oral parasetamol dosis 2000 mg/kg berat badan pada hari ke 9, 2 jam setelah pemberian ekstrak buah delima dan silymarin. Ekstrak dari buah delima diberikan secara oral dengan dosis 200 mg/kg dan 400 mg/kg BB dan silymarin diberikan secara oral dengan dosis 100 mg/kg setiap hari selama 9 hari. Beberapa penanda seperti SGOT dan SGPT diukur untuk menilai efek ekstrak pada kerusakan hati yang disebabkan oleh parasetamol. Sampel darah dari tikus yang diberi ekstrak buah delima 200 mg / kg BB dan 400 mg / kg BB memberikan kadar SGOT dan SGPT yang lebih rendah di bandingkan kontrol negatif (paracetamol) menunjukkan efek ekstrak dalam mencegah kerusakan akibat hepatoksin, akan tetapi efek yang diberikan belum mampu menyamai kontro positif pada kadar SGOT. Silymarin digunakan sebagai obat kontrol positif. Sehingga perlu adanya penambahan waktu pemberian dan dosis dari ekstrak buah delima sehingga efek yang dihasilkan lebih baik. Kata Kunci : Buah Delima, Hepatoprotektif, SGOT, SGPT, Parasetamol
UJI EFEKTIFITAS EKSTRAK DAUN KOPI ROBUSTA (Coffea Robusta) SEDIAAN GEL TERHADAP BAKTERI Propionibacterium acnes
Authors: Marcellia Selvi , Tutik Tutik , Romadhon Sukma
Published: April 2022

Jerawat merupakan masalah kulit yang sering dialami oleh masyarakat terutama usia remaja. Jerawat disebabkan oleh bakteri Propionibacterium acnes. Daun kopi robusta memiliki khasiat sebagai anti jerawat. Zat aktif pada daun kopi robusta dapat diperoleh dengan ekstraksi menggunakan metode perkolasi dengan pelarut etanol 96%. Metode perkolasi leih efektif dibandingkan dengan metode maserasi karena menghasilkan rendemen yang lebih sempurna. Pada uji fitokimia menunjukan bahwa didalam ekstrak daun kopi robusta positif mengandung alkaloid, tanin, flavonoid dan saponin. Ekstrak daun kopi robusta yang diperoleh dibuat dalam sediaan gel dengan konsentrasi 0,1%, 0,5% 1% dan 2%. Evaluasi gel meliputi uji aya sebar, uji daya lekat, uji homogenitas, uji pH dan uji organoleptis. Uji daya hambat gel ektrak daun kopi robusta menggunakan metode difusi sumuran. Efektifitas zona hambat tertinggi yang terbentuk pada konsentrasi 2% sebesar 28.38%. Hasil uji antibakteri dianilisis menggunakan ANOVA. Hasil analisis statistik menunjukan ada perbedaan zona hambat yang signifikan yaitu nilai p=<0,005 antara seluruh konsentrasi gel ekstrak daun kopi robusta. Semakin tinggi konsentrasi gel ekstrak daun kopi robusta maka semakin luas diameter zona hambat. Gel ekstrak daun kopi robusta efektif dalam menghambat bakteri Propionibacterium acnes. Kata kunci : Propionibacterium acnes, Jerawat, Gel ekstrak daun kopi robusta.
FORMULASI SEDIAAN GEL EKSTRAK KULIT BAWANG MERAH (Allium cepa L.) SEBAGAI ANTIJERAWAT TERHADAP BAKTERI Propionibacterium acnes
Authors: Tutik Tutik , Feladita Niken , Evaliana Kadek
Published: April 2022

Bakteri Propionibacterium acnes merupakan bakteri gram positif berbentuk batang, yang merupakan flora normal kulit, namun pada kondisi tertentu bakteri menimbulkan jerawat. Tujuan dari penelitian ini adalah untuk mengetahui berapakah konsentrasi minimum yang paling efektif ekstrak bawang merah sebagai gel antijerawat. Penelitian ini melakukan  ekstraksi kulit bawang merah menggunakan metode maserasi dengan pelarut etanol 96%. Hasil rendemen dari ekstrak kulit bawang merah diperoleh sebesar 9,8%. Hasil ekstraksi diuji KHM kemudian hasil KHM digunakan untuk membuat formulasi gel. Pengujian daya hambat ekstrak kulit bawang merah dan sediaan gel ekstrak kulit bawang merah dilakukan dengan mengunakkan metode sumuran. Konsentrasi hambat minimum (KHM) yang menunjukkan daya hambat adalah 5% dengan rata-rata zona hambat 5,07mm. Kemudian dibuat sediaan gel dengan basis carbopol dan konsentrasi ekstrak sebesar 5% dan 10%. Formulasi terbaik dari sediaan gel yang dibuat adalah sediaan gel dengan konsentrasi ekstrak sebesar 10%. Konsentrasi ekstrak kulit bawang merah dalam sediaan gel antijerawat yang paling efektif dalam menghambat bakteri Propionibacterium acnes adalah sebesar 10% dengan zona hambat 10,50mm. Kata kunci: Gel, Kulit Bawang Merah, Antibakteri, Propionibacterium acnes
PENGARUH KONSENTRASI PELARUT TERHADAP AKTIVITAS ANTIOKSIDAN DAN KANDUNGAN TOTAL FLAVONOID EKSTRAK ETANOL KULIT BAWANG MERAH (Allium cepa L.)
Authors: Wahyuni Nadiya Eka , Yusuf Mashuri , Tutik Tutik
Published: April 2022

Kulit bawang merah (Allium cepa L.) yang masih kurang dimanfaatkan mengandung senyawa flavonoid yang sangat berpotensi sebagai antioksidan. Tujuan penelitian ini untuk mengetahui pengaruh konsentrasi pelarut terhadap aktivitas antioksidan dan mengukur kadar flavonoid dalam ekstrak etanol kulit bawang merah. Metode penelitian ini mengekstraksi kulit bawang merah dengan metode maserasi menggunakan pelarut etanol dengan variasi konsentrasi. Hasil ekstraksi diukur aktivitas antioksidan dengan metode DPPH dan kadar flavonoidnya. Hasil ekstraksi diperoleh % rendemen terbaik dari proses ekstraksi di dapatkan pada ekstrak yang menggunakan pelarut etanol 96% yaitu sebesar 28,88%. Hasil uji aktivitas antioksidan diperoleh nilai IC50 terbaik didapatkan pada ekstrak dengan pelarut etanol 96% yaitu sebesar 34,74 ppm. Hasil pengukuran kadar flavonoid terbesar juga didapatkan oleh ekstrak dengan pelarut etanol 96% yaitu sebesar 948,33 mg QE/g. Konsentrasi dari pelarut mempengaruhi aktivitas antioksidan dan kadar flavonoid ekstrak etanol kulit bawang merah.
Economic security of small and medium-sized businesses: substantive essence, approaches to management
Authors:   MIREA – Russian Technological University, Filobokova Ludmila Yu. , Nyarginen Victoria A. ,   Market Economy Institute of RAS,   MIREA – Russian Technological University
Published: April 2022

Small and medium business in Russia is a significant element in the system of the national economy of Russia, the functional role of which, in the process of its evolution at the present stage of development, has been transformed into a factor in the formation of a competitive environment. The presence of a developed competitive environment is considered as one of the basic conditions for ensuring sustainable socio-economic development of the country and improving the quality of life of its population. A competitive environment is possible to be formed in conditions of a high level of competitiveness of the «Small and Medium Business» system and its economic security. The problems of economic security are insufficiently studied and the relevance of such research is growing when it comes to small and medium-sized businesses, for the safe and sustainable development of which a scientific and methodological justification of management is necessary. This article presents the main results of a study on the development and justification of such provision: an interpretation of the definition of «economic security» and its local components by system levels is given, the need for institutional changes is proved, and a model of institutional changes of the innovation-integration type is proposed. The purpose of the study is the theoretical and methodological substantiation of the content essence of the category «economic security of small and medium-sized businesses», the establishment of links and relationships (elements of local security) of the state of security, considered as a result of the integration of local states of security, as well as the development of one of the alternative models of strategic management of economic business security in small organizational and economic forms of management. As part of the researching, the authors used an information-methodological approach, the methodology of strategic analysis and planning. The results of the study presented in the article should be considered as intermediate.
La commémoration de la sphère publique à la classe d’histoire : réflexions autour de la commémoration du 375e anniversaire de Montréal
Authors: Déry Chantal , Girard Emilie , Desnoyers-Collin Marie-Pierre
Published: April 2022

In 2017, the city of Montreal commemorated its 375th anniversary. It is in this context that we offer an overview of the characteristics of commemoration and more specifically we take a closer look at those lived in Montreal since the beginning of the 20th century. Based on this brief analysis, the second half of the article presents a tool to address commemoration in the history classroom with primary and high school students in order for them to better grasp the mechanisms behind the practice of commemoration and to help them built a citizen’s view of commemoration
La didactique de l’Information-Documentation en France comme ressources pour l’enseignement : une histoire et une « épistémologie plurielle »
Authors: Frisch muriel
Published: April 2022

Information-Documentation didactic in France as teaching resources: an history and a «plural epistemology». This text is based on our research Information-Documentation didactic. It focuses on the epistemological and historical dimensions developed in our Habilitation Thesis (2016) and uses a review of the literature. This paper is thus going to be organized into four parts: characterization of what we call a “plural epistemology”; origins and history of Documentation-Information training in Education; neighboring fields, complementary and identification of trends, paradigms and models dominant; documentary culture, Information-Documentation didactic and link with teaching of history.
Pourquoi enseigner l'histoire, et pourquoi enseigner l'histoire à l'école élémentaire ?
Authors: Souplet Catherine
Published: April 2022

This paper chooses to talk about history teaching, considering in particular its purposes. The aim is not to deliver a dogmatic reflexion, but rather to invoke others papers and authors’ propositions to think with them from a didactic point of view. The intent is to deliver a way to consider school history purposes, considering its practices, especially in primary school.
Il lessico della Shoah per una produzione linguistica creativa. Esempio di un percorso metodologico-didattico basato sul concetto di multiliteracies
Authors: Gentilin Olivetta
Published: April 2022

The present paper describes the development of a learning unit for German learners about different aspects of the Shoah. The theoretical basis follows the pedagogical design of multiliteracies both as regards the structure of the unit and the variety of proposed texts and media. Firstly, the students acquire knowledge of the past through the analysis of medial and written texts. In this phase they focus on the use and function of words related to the Shoah. Then they apply what they have learnt by producing creative poetry, using digital resources. In this way they have the opportunity to reflect on the past by comparing it with their own thoughts and opinions. The connection with present situations aims at making students rethink behaviour models.
Histoire de l’Holocauste et éducation aux droits humains: arrimage réussi au Québec?
Authors: Moisan Sabrina , Bélanger Audrey
Published: April 2022

This article focuses on the twinning of history teaching and human rights education. The case of the Holocaust illustrates the possibilities and limits of such a relationship, in light of the practices implemented in history and citizenship education classes in Quebec. Organized around four axes of analysis, the results show that the teachers privilege above all an awareness to the human rights and a teaching centered on the knowledge of the rights. Similarly, Holocaust education focuses on the Nazi efforts to persecute Jews without explicit references to human rights issues. Both subjects are studied separately in the same sequence.
MSCEIT emotional intelligence test: description, validization and adaptation
Authors: Shyron Yu.
Published: April 2022

The article presents the description and results of adaptation of the test of determining the level of emotional intelligence MSCEIT (The Mayer-Salovey-Caruzo. Emotional Intelligence Test), American researchers J. Mayer, P. Salovey and D. Caruso, based at the National University «Lviv Polytechnic» in order to use this technique in further studies of the impact of this indicator on the productivity of employees. The choice of the specified technique among the existing objective test methods is substantiated. The test was developed by the authors based on their own four-component structural model of abilities as an objective test of emotional intelligence. This technique covers two subtests for each component of emotional intelligence of this concept. The MSCEIT emotional intelligence test was adapted according to standard algorithms for adapting foreign language psychodiagnostic tools: the English version was translated into Ukrainian, retest reliability, reliability of parallel forms and internal consistency (Cronbach's alpha) were tested. A comparison of the results of the general sample of students and specialists in psychological and economic specialties (N = 468) and a sample of experts consisting of a doctor of psychological sciences and candidates of psychological and economic sciences who are researchers of emotional intelligence (N = 10). Testing was conducted by filling out blank test forms and calculating the results obtained by consensus and expert methods, respectively. Based on the results of the testing, a set of keys for the adapted MSCEIT test was obtained. The retest reliability study was conducted three weeks later. The reliability of parallel forms was carried out using the methods of subjective survey of D. Goleman and M. Hall. The high level of subjectivity of methods in the form of questionnaires determines the dependence of the results obtained on the level of self-esteem. In order to confirm the reliability of the results of the reliability of parallel forms, a study of the level of self-esteem of the sample of individuals using the method of «I am real» and «I am ideal».
Search engine marketing
Authors: Ivanechko N. , Dudar V. , Pavelko V.
Published: April 2022

The article considers the elements of Internet marketing. It is determined that search marketing is a search engine optimization and a modern method of site promotion by optimizing the resource for social networks. The classification of search queries is carried out according to the following features: query competitiveness, query frequency, query value, query geodependence, query regionality, query seasonality, query time of day. It is established that the sign of competitiveness of the request is divided into highly competitive, medium competitive, low competitive; the query frequency attribute is divided into high-frequency, medium-frequency, low-frequency; the degree of value of the request is divided into commercial and non-commercial; sign of geodependence of the request for non-independent and geo-dependent requests. The advantages and disadvantages of SEO and contextual advertising are found. Advantages of SEO are as follows: the presence of the site in search engines adds credibility and confidence in consumers; has good clickthrough rate; can show simultaneously several links of the same site in the TOP 10; in the long-term strategy the cheapest of all channels to attract traffic to the site; when you stop promoting the site, search positions are stored for up to 1 year; the effect of promotion affects all search engines; there is no threat to «convene» the budget by competitors. Advantages of contextual advertising are: fast traffic; full control over the ads and the ability to make changes quickly; independence from updates of search engine algorithms; the ability to set fixed daily budget, after reaching the set metric ads will stop running. The main disadvantages of SEO are: long lead times; change in the algorithm by search engine can dramatically affect the result; threat of sanctions against the site; it is impossible to predict the actions of the search engine in advance. The main disadvantages of contextual advertising are the following: the consumer understands that he goes to the company's website for advertising; when the money runs out, consumers will stop going to the site; in the end it can be very expensive; cost-per-click is constantly changing. The common disadvantage of these two elements is the lack of guarantees for the purchase of goods or services in any case.
Training Aircraft Selection of the Vietnam People's Air Force Using a Hybrid BWM-Fuzzy TOPSIS Method
Authors: Ma Jungmok
Published: April 2022

Demands that the Vietnam People's Air Force (VPAF) have new modern training aircraft have been growing recently. Although other training aircraft such as the Yak-52 and L-39 have performed well for decades, they are no longer able to perform the full range of training tasks required of them due to an increasing technology gap. In 2016, the United States government lifted a decade-long ban on lethal arms sales for Vietnam. This has created opportunities for Vietnam to access a variety of weapons suppliers from many countries that have a strong, global defence industry. However, one of the most difficult decisions the VPAF must make concerns the type, configuration, and capabilities of future training aircraft. This study therefore proposes a Multi-Criteria Decision Making (MCDM) model by combining the Best Worst Method (BWM) and a Fuzzy Technique for Order of Preference by Similarity to Ideal Solution (Fuzzy TOPSIS) to choose a modern training aircraft that can replicate the characteristics of several fourth-generation or better fighter planes, with the fifth-generation fighters also being able to perform light-attack and reconnaissance duties for VPAF. The case study employing the hybrid BWM-Fuzzy TOPSIS method reveals that the Yak-130 training aircraft is the best selection for VPAF. To validate the robustness of the proposed framework, sensitivity analysis has been conducted with the result compared to Analytic Hierarchy Process (AHP).
Colonisation then and now in Avanersuaq
Authors: Binachon Martin
Published: April 2022

How does colonialism affect the Inughuit People of Avanersuaq today? In October and November 2021, I went to Qaanaaq, Ilulissat and Nuuk to find out.
Avanersuarmi nunasiaataasimaneq ullukkumullu
Authors: Binachon Martin
Published: April 2022

Inughuit Avanersuarmiut nunasiaataasimanerat ullumikkumut qanoq sunniuteqarsimava? Tamanna paasiniarlungu Qaanaaq, Ilulissat taavalu Nuuk Oktobari Novembarillu qaammataanni, 2021, tikeraarpakka.