bluuebunny/crossref_metadata_2025 huggingface dataset:
ФОРМУВАННЯ КОМПЕТЕНТНОСТЕЙ УЧАСНИКІВ ОСВІТНЬОГО ПРОЦЕСУ НА ОСНОВІ ХМАРО ОРІЄНТОВАНИХ ІНФОРМАЦІЙНО-ОСВІТНІХ СИСТЕМ
Authors: Биков Валерій Юхимович
Published: March 2021

Представлено основні результати виконання комплексу наукових досліджень, що здійснювалися у 2018-2020 рр. в Інституті інформаційних технологій і засобів навчання НАПН України, з проблем формування компетентностей учасників освітнього процесу на основі хмаро орієнтованих інформаційно-освітніх систем: 1. «Адаптивна хмаро орієнтована система навчання та професійного розвитку вчителів закладів загальної середньої освіти» (фундаментальне, керівник — д-р пед. наук, с.н.с. М.П. Шишкіна); 2. «Система комп’ютерного моделювання пізнавальних завдань для формування компетентностей учнів з природничо-математичних предметів» (фундаментальне, керівник — д-р пед. наук, с.н.с. С.Г. Литвинова); 3. «Методика використання відкритих електронних науково-освітніх систем для розвитку інформаційно-дослідницької компетентності наукових і науково-педагогічних працівників» (прикладне, керівники — канд. пед. наук, с.н.с. А.В. Яцишин, канд. пед. наук С.М. Іванова). Особливу увагу в доповіді приділено впровадженню результатів досліджень у практику закладів загальної середньої освіти, вищої та післядипломної педагогічної освіти. Презентовано розроблені та апробовані на практиці методики, навчально-методичні матеріали. Системоутворювальними чинниками комплексу наукових досліджень є: загальна мета, єдиний базовий методологічний фундамент досліджень (системний, компетентнісний і проєктний підходи), комплексний характер їх одночасного проведення і впровадження, взаємозумовленість основних кінцевих результатів (сформованих цифрових компетентностей учасників освітнього процесу), хмарна комп’ютерно-технологічна платформа досліджень і реалізацій освітніх застосувань.
Systematic Review as A Research Design: A Brief Overview
Authors: L Manoj Kumar
Published: March 2021

Systematic reviews and meta-analyses are proliferating in medical literature. Systematic reviews areconducted widely in medical science to answer focused and specific clinical research questions. Researchersemploy a predetermined, explicit and progressive systematic methodology to comprehensively search for,select, formally evaluate, analyze and cumulate the studies which gives results for stated research problem.Meta-analysis; a further statistical step of systematic review is the statistical pooling of the results of studies.Systematic reviews critically appraise and synthesize the best available evidences and findings to provide aconclusion statement in regards to a specific answerable research question. The fame of systematic reviewand its application are scarce in India especially in nursing science. This paper tries to simply draw basicsteps and concepts of Systematic review, along with guidelines and core methodology to be adopted whiledoing a Systematic review.
Assessment of the Level of Coping Strategies in Patients with Depression Attending Psychiatric Outpatient Department at Selected Teritary Care Hospitals Coimbatore
Authors: Ramachandran Remya , Esther Sherlin. P Beulah , Majrin Esther Lydia , Metilda K Ann Metilda K , P Poonesh
Published: March 2021

Depression is one of the four major diseases in the world. Patients with depression uses different coping stylesto cope up with their problems. The objective was to assess the coping strategies adopted by the patients withdepression and to find out the association between coping strategies and selected demographic variables. Thedescriptive study was undertaken among patients with depression and non-probability purposive samplingtechnique was used. The data was collected using structured questionnaire. In overall 60% of patients havemoderate level of coping strategies, 30% of patients have inadequate level of coping strategies and 10% ofpatients have adequate level coping strategies. There was significant association between the level of copingstrategies and the demographic variable like domicile. This study concluded that selected patients withdepression had moderate level of coping strategies.
Effect of a Brief Intervention on Anger Management among Adolescents
Authors: A Uma Maheswari , Rathinasabapathy Baby , Nagarajan Padmavathi
Published: March 2021

Background: Adolescence is the transition period between childhood and adulthood, during which anindividual experiences a number of emotional issues. Adolescents’ anger may be triggered and/or intensifiedby variety of factors. To be healthy and safe, adolescents need to be equipped with skills that allow themto cope with anger in a productive manner. This study was aimed to assess the effect of anger managementtechniques on the level of anger among adolescents.Method: An experimental pre-test, post-test design was adopted to achieve the objectives of the study. Asimple random sampling technique was used to select 120 adolescents, studying at Government schools ofPuducherry. Socio-demographic details were collected by a semi-structured proforma. The level of anger wasassessed by Adolescent anger rating scale before and after the intervention. Anger management techniquessuch as deep breathing exercises, assertive communication and the techniques to improve interpersonalrelationship were taught to the subjects over a period of one-week.Results: Majority of the subjects was in the age group of 14 years, in both the experimental (n=28, 46.67%)and control group (n= 26, 43.33%). There was a significant reduction in the level of anger among theexperimental group from the pre-test mean (SD) score of (92.5 ± 19.13) to post-test (68.95 ± 11.58) and thepaired ‘t’ test value (12.91) demonstrated that the difference was statistically significant at p<0.001.Conclusion: The study results indicate that anger management intervention was effective in reducing thelevel of anger among adolescents. The techniques adopted in the study are simple and cost effective and theregular practice of these techniques would definitely enhance the coping skills of adolescents in controllingtheir anger.
Association between Patient’s Educational Degree with Level of Knowledge and Perception Regarding Pulmonary Tuberculosis
Authors: Mohammad Subkhan  , Rahmat Sayyid Zharfan  , Ricky Indra Alfaray  , Kamal Musthof
Published: March 2021

Background: Indonesia is the second largest population of pulmonary tuberculosis (TB) worldwide.Unfortunately, this condition has remained unchanged past decade. Education is essential for the formationof knowledge and perception, which is important, due to its impact on tuberculosis treatment implementation.Objective: The aim of this study is to determine the association between patient’s educational degree withknowledge and perception regarding pulmonary tuberculosis.Method: This was observational analytic study with cross-sectional design. The study was conducted on 51patients in TB outpatient clinic from Siti Khodijah Hospital and two Primary Health Care in Sidoarjo. Usingsimple random sampling, a questionnaire was formed to obtain related information about the variablesstudied; including baseline characteristic (age, gender, education, occupation), patient’s knowledge,and perception regarding pulmonary tuberculosis. Then parameter’s of knowledge and perception wereclassified: good and low.Results: Using multivariate analysis of Wilcoxon test, there was a significant difference between each groupof patient educational degree with knowledge regarding tuberculosis (p = 0.00) and perception regardingtuberculosis (p = 0.00).Conclusion: Different patient educational degree shows different knowledge and perception regardingPulmonary TB. This result may indicate that the educational degree affected the patient to understand thedisease. The collaborative approach needed to build proper patient’s knowledge and perception. Lack ofknowledge regarding TB, may due to a deficiency in Indonesian school curriculum content. These resultswill inform the development of relevant education, and information system, to enhance awareness abouttuberculosis in society.
An Updated Review on Some Neurotoxicpharmacological Agents Along with their Neurotoxic Mechanisms
Authors: Muhammad Irfan Bashir  , Nur Hidayah Kaz Abdul Aziz  , Dzul Azri Mohamed Noor
Published: March 2021

This review will provide the vital information about some pharmacological agents which are Neurotoxic.Through this update, Anti-cancer, Anti-bacterial, Analgesic, Psychoactive drug and Anabolic steroidmedication are reported briefly regarding their neurotoxic mechanisms. In this review all informationregarding neurotoxic drugsis collected from 2020 published work by Web of science, Scopus, PubMed andGoogle Scholar. It is concluded that all these drugs which the part of our study areneurotoxic. There is needto discover some methodto reduce their toxicity and to avoid the chronic use of these medications.
Effects Of Pigeon PEA (Cajanus Cajan) Consumption to Decrease Blood Pressure on Elderly Hypertension in the Region of Barana Health Center of Jeneponto
Authors: Muhammad Khidri Alwi  , Sri Julyani  , Yusriani, Nurfardiansyah Burhanuddin  , Sulfiana S  , Burhanuddin Bahar
Published: March 2021

Hypertension is a high-risk condition that causes of deaths, stroke, and coronary heart disease. This studyaims to determinethe effect of giving pigeon pea (Cajanus cajan) baruasa on systolic and diastolic bloodpressure of elderly with hypertension.The research is quasy experimental design with pre-post test group. A total of 36 elderly people withhypertension were divided into intervention group and control group by random sampling. Data wereanalyzed using Mann-Whitney and Wilcoxon with 95% confidence level.The results of this study indicate that: There is an effect giving pigeon pea (Cajanus cajan) baruasa on thesystolic blood pressure of elderly with hypertension (p = 0.001 <0.05); (4) There is an effect giving pigeonpea (Cajanus cajan) baruasa to the diastolic blood pressure of elderly with hypertension (p = 0.001 <0.05).The conclusion of this study that consumption of pigeon pea (Cajanus cajan) baruasa can reduce of bloodpressure on elderly hypertensive in Jeneponto district.The suggestions for researcher presumably can further investigate the influence of pigeon pea baruasa onblood pressure in elderly man with hypertension and long storage time (expiration date) of pigeon peabaurasa
Association between Effect Ofsome Pro-inflammatory and Anti-inflammatory Cytokines before and After Surgical Patients
Authors: Muntasser Alawi Awad  , Firas Hasan Hadi  , Nada Fadil Abbas
Published: March 2021

The aims of our study were to investigate association of some effect of pro- inflammatory and antiinflammatory cytokines before and after surgical patients through study serum concentration of, TNF-?,IL-2, IL-4, IL-6, IL-10. 35 blood samples were collected from surgical patients (17 male, 18 female)withgeneral anesthesia from Al-Diwaniyah Hospital, Iraq. Samples were taken before surgery (Tpre), the firstday) T1), third day) T3 (and fifth day (T5) after operative after skin incision.Pro-inflammatory cytokines(IL-2, IL-6, and TNF-?) and anti-inflammatory cytokines (IL-4, IL-10) were quantitatively analyzed byELISA technique.Our resultsshowed there were no significant difference (p<0.05) in WBCs count, WBCspercentage (neutrophil, eosinophil, basophil, monocytes and lymphocytes), PCV, PCT percentage and HBconcentration before (Tpre) and after (T1, T3, and T5) surgical operation. Also the results showed therewere a significant decrease in IL-2 concentration in (T1) and (T3) day postoperative surgery comparedwith (T pre), and returned to the pre-operative values on (T5). IL-6 showed significant increase in first daypostoperative (T1), and then decreased the (T3 and T5) compared to the (Tpre), TNF? slightly increasedin (T1 and T5) but the difference didn’t significantly, IL-4 didn’t show any significant difference betweenTpre, T1, T3 and T5. IL-10 showed a significant increase in (T1) compared with (Tpre), and returned tothe preoperative values on (T3) and (T5). We could be concludethe pro? and anti?inflammatory cytokinesbalanced ratio is essential to regulate the inflammatory responses postoperative. Anti-inflammatory cytokine(IL-10) increased in first day postoperative to suppress excessive effect of pro-inflammatory cytokine (IL-6).
Dental Medicine Students Perception on the Effectiveness of Problem Based Learning (PBL) Class Using Online Learning Method
Authors: Nicholas Ezra  , Aryo Dwipo Kusumo  , Kamilia Fahmi Ag  , Fathimah Hanan  , Naurah Nabilah Pramaztri  , Leila Isyafitri  , Mohammed Alaqsha Brysoul Ceson
Published: March 2021

Background: The main concern of universities is regarding the quality and effectiveness of education. Atotal of 32 dentistry faculties in Indonesia have implemented Problem Based Learning (PBL) classes in theirlearning curriculum. Some dentistry faculties have actively used student-centered learning method, andare no longer teacher-centered. According to the results of the 2017 Indonesian Internet Service ProvidersAssociation, the prevalence for Indonesian (Undergraduate/Diploma) students as Internet users reached79.23%.Purpose: To describe the perception of Universitas Airlangga Faculty of Dental Medicine students on theeffectiveness of the Problem Based Learning (PBL) class using the Online Learning method.Method: Data was collected from the distribution of questionnaires to students of Universitas Airlangga,Faculty of Dental Medicine semesters 1, 3, 5, and 7. Then a descriptive statistical test was conducted.Results: The percentage of respondents who considered effective Problem Based Learning (PBL) classesusing online learning method was 52.4%, very effective at 5.8%, very ineffective at 2.9%, no opinion at14.6%, and ineffective at 24.3%.Conclusion: The majority of Universitas Airlangga Faculty of Dental Medicine students have an effectiveperception of the Problem Based Learning (PBL) class using the Online Learning method.
Estimation of Difference in Rate of Healing of Contusions in Diabetic, Hypertensive and Anemic Persons by Subjective and Objective Analyses
Authors: Nisha Nandakumar  , Prasannan K  , Nisha T.R
Published: March 2021

Background and Objectives: Age of injuries have several medicolegal implications including assault,abuse,criminal conjectures etc. Contusions are wounds characterized by effusion of blood into tissuespaces caused by forceful impact of blunt objects. Its colour changes reflect the natural healing process,though these changes donot occur uniformly and depend on the size of contusion, age and physique of theperson and also presence or absence of diseases. This study was aimed at estimating the delay in healingof contusions in diabetic, hypertensive and anemic persons by gross examination and objective analysesincluding examination under Woods lamp, magnification of digital photograph, and histologic changes tovalidate the age as per available history.Method: This is an autopsy based prospective study over a period of 1 year (Feb 2015-Feb 2016),involving50 cases of contusions conducted in Department of Forensic Medicine, Govt Medical College Calicut. Thedata obtained were analysed by SPSS software version 18. Comparison of different components, the level ofcorrelation between various variables and significance of association were determined, and sensitivity andspecificity of various method of analyses in determining the age of wounds were established.Conclusion: Grossly,contusions were red < 24 hours old, bluish black on day 2, greenish on day 3 andyellow on day 7 as was seen in magnified digital photograph.There is increasing positive agreement between colour of wound assessed from magnified digital photographand period of survival from day 1 to day 5-6 and decreases thereafter in normotensives, hypertensives andnon diabetic subjects whereas it drops drastically after 7 days in diabetics.The association between colour of contusion under Woods lamp and survival period increased from day 1to reach maximum on 5-6 days.There is significant positive association between presence of hypertension,as in diabetes, and histologicaldelay in healing of contusions whereas no significant association was found with anemic status.
An Epidemiological Analysis of Deaths Due to Burns in Newly Married Females
Authors: Nisreen Abdul Rahman  , Shanmugam K.  , Sanjay Sukumar  , Kusa Kumar Shaha
Published: March 2021

Death due to burns is a major public health problem worldwide. Most cases occur in middle and low-incomecountries. In India, deaths due to burns are commoner in women than in men. Fire is easily available weaponfor suicide and homicide and it can also cause accidental deaths. Death due to burns in newly marriedfemale is a common incident in our country and major fraction of such deaths happen as a result of dowryharassment or killing for not giving dowry. Our study aimed to identify some of the epidemiological factorsin deaths due to burns in newly married females in and around Pondicherry. Out of 48 cases during the studyperiod, 24 victims were in the age group of 22-25 years and 26 women died within 3 years of marriage.The majority of the cases occurred in less educated and homemaker wives and were living in a joint family.Major reasons or motive behind deaths were dowry harassment and torture, and quarrel with husband or inlaws. The most common manner of such deaths was suicidal followed by accidental.
Green Biosynthesis of Silver Nanoparticles Using Gallium aparine Green Part Extract and Anti-skin Cancer Activity.
Authors: Omar Hasnawi Hamdi  , Shurook M.K. Saadedin  , Iqbal Harbi Mohammed AL_ZAIDI
Published: March 2021

Background: Galium aparine has a long history of use as an alternative medicine and is still used widely bymodern herbalists. It is a fabulous diuretic that is often taken to treat skin problems. It treats many problemssuch as seborrhoea, eczema, psoriasis. It also acts as a great detoxifying agent in life-threatening ailmentslike cancer. Skin cancer is the most common type of cancer in light skinned populations around the world.Aim: The aim of the study was to evaluate the anticancer efficacy of greensynthesised silver nanoparticles(AgNPs) of Gallium aparine extract.Method: The green part of the plant G.aparne extracted with ethanol 70%, then divided into four fractionsto prepare stable AgNPs .Results: Several tests were performed to examine the extracts and AgNPs, including SEM,FTIR and UVVS. Scanning electron microscope(SEM)micrographs showed that the diameters range of AgNPs formedwere from 35-110 nm.Fourier transform infrared (FTIR) shows that there were two functional groups, thearomatic (C=C) and hydroxyl (– OH), groups may be involve in the fabrication of AgNPs. UV-VS showsthat there were a peaks at 298,448, 534, 606, 648, for nanoscale petroleum ether extract. These peaks maybeindicate the synthesis of AgNPs. Different concentrations (6.225 - 400 µg/ml), of petroleum ether extractand its green AgNPswere tested as anti-skin cancer, the nanoparticles had appositive effect against cancer,the IC50 for the petroleum ether extract was 730.2 and 116.5 of normal cell line (WRL 68) and cancer cellline (A375), respectively,while the IC50 for the AgNPs of Gallium aparine extract was 294.4 and 77.03ofnormal cell line (WRL 68) and cancer cell line (A375)respectively.Discussion: This indicates that the G. aparine extract is a good biological carrier for synthesizing silvernanoparticles which has potential for various biomedical and pharmaceutical applications.Conclusion: AgNPs have been successfully synthesized using G . aparian extract, The nanoparticles haveshown good anticancer activity towards human skin cancer cells.
Application of Colaizzi’s Method of Data Analysis in Phenomenological Research
Authors: Praveena K.R  , Sasikumar S
Published: March 2021

Background: Phenomenology is a research method intended to explore the experiences of people as theylive in different phases of their life. Aim: This paper aimed to explore the Colaizzi’s method of descriptivedata analysis to articulate the experiences of women living with Ischemic heart disease (IHD).Method: By using the actual research data, the technique of Colaizzi’s data analysis was used to extract,organize and analyze the data.Results: Colaizzi’s strategy was effectively utilized in identifying significant statements from the transcribedverbatim and meanings were formulated. From these formulated meanings clusters of themes and themeswere derived which eventually helped in the development of thematic map of experiences of women withIschemic heart disease (IHD).Conclusion: Colaizzi’s step of data analysis in descriptive phenomenology was effectively utilized in thisresearch that facilitated in reflecting the experiences of IHD patients.
Assessment of Women’s Satisfaction with Childbirth Experience after Utilization of Pain Management Practices at Al-Elwyia Maternity Teaching Hospital
Authors: Rabea Mohsen Ali
Published: March 2021

A quasi-experimental study conducted on non-probability of (30) women whom admitted to Al-ElwyiaMaternity Teaching Hospital suffering from labor pain for the period of (4th July 2018 through 24th October2018). The results how that the highest percentages of non- pharmacological method used was frankincenseoil, and related to women perception of labor pain they are assessed high as general, and they are accounted24(96.0%). The study concluded that women’s satisfaction with childbirth experience after utilization painmanagement practice’s items showed good status, since highly evaluation was obtained, and that reflectedthe positive site of effectiveness for the intervention which were applicable indeed. So that constructioncontinuous education program about non-pharmacological pain management practices to all midwifeworking in delivery room and department of maternity is need.
Evaluation of a New Green Zirconium Nanoparticle from Lemon and Peel Extract Antioxidant and Anticancer Activity
Authors: Rajaa H. Salih  , Sundus Hameed Ahmed  , Rasha Sattam Hameed  , Isam Hussain T. Al-Karkhi
Published: March 2021

Objective: This study was planned to synthesizea novel green Zirconium nanoparticles (ZrNPs), fromlemon/and lemon peel with zirconium salt and test its bioactivity against free radicals, and certain cancer celllines (MCF-7).Materials and Method: Lemon/peel extracts were prepared, mixedwith water and heated to80 °C, and filtered. The zirconium nanoparticles were synthesized using (ZrCl3) solution which was addedto the filtrate (juice and peel) in 1:1 proportion, and UV-Visible was taken. Different concentrations wereprepared to study their activity. DPPH assay against free radicals and cytotoxicity against MCF-7 cell linewere measured. Results: UV-Visible absorbance of lemon peel/and lemon NPs was carried out and it wasfound that NPs gave peaks at 457 and 478 nm, while lemon NPs gave peak at 217, and 270 nm. antioxidantactivity of all the solutions were carried out, it was found that the peel and juice nanoparticles gave thehighest scavenging activity % in all concentrations at 800, 600, 400, and 200 µg/ml which were 93, 78, 57,and 20% respectively. The activity against MCF-7 cancer cell line, the highest inhibition percentage effect(95.16) showed by NPs + Peel, while the lowest effect was 18.42.Conclusion: Novel NPs were synthesized form ZrCl3 and lemon extract/and lemon peel, it was found thatthe last one is more active against free radical and MCF-7 cell line.
Effectiveness of Jacobson’s Progressive Muscle Relaxation (JPMR) on Hypertension among School going Adolescents
Authors: Rajagopal Manjushambika  , Baby Prasanna  , R. Vijayaraghavan  , Bai Sushama
Published: March 2021

Background: Hypertension could have its origin in childhood and go undetected unless specially lookedfor. Though many risk factors were postulated for hypertension among adolescents, gap in knowledge is thatno studies are reported on effectiveness of interventions for hypertension among adolescents.Objectives: To determine: 1) effectiveness of JPMR on blood pressure. 2) association of blood pressureto selected variables. Basic procedure: In first phase, a cross-sectional survey was conducted among980 adolescents following multistage stratified random sampling from classes 6th to 12th. Anthropometricmeasurements, HR, BP and selected blood tests were done. In second phase experimental approach withpre-test, post-test control and experimental was done with JPMR as intervention.Main Findings: Both rural and urban adolescents were in par with regard to prevalence of hypertension.There was significant association between hypertension and family history. Prevalence of hypertensionamong 14-17 years was higher than 11-13 years. Prevalence of hypertension among overweight and obeseadolescents was significantly higher than their counterparts. Mean post-test systolic and Diastolic BP ofexperimental groups in both rural and urban areas were significantly lower than their pre-test values and thepost-test values of their counterparts suggesting JPMR was effective.Conclusion: JPMR is an effective intervention for adolescent hypertension. Relaxation techniques can bemade as part of curriculum in schools.
Evaluation of Eustachian Tube Function on Chronic Suppurative Otitis Media
Authors: Rosydiah Rahmawati  , Haris Mayagung Ekorini
Published: March 2021

Introduction: Many literatures reported that poor aeration in the middle ear due to Eustachian tubedysfunction is an important factor that plays a role in causing acute and chronic otitis media.Objective: To assess Eustachian tube function (ETF) and to confirm Eustachian tube condition duringsurgery on chronic suppurative otitis media (CSOM) patients.Method: This study employed a prospective design, in which participants were examined for ETF beforeand after surgery. The examination used Toynbee’s procedure with impedance audiometry. The examinationresults were analysed using Pearson’s product-moment test with p < 0.05.Results: The average patient’s age was 36.27 ± 5.98 years, with an age range of 12 to 67 years. Mostparticipants had no cholesteatoma (59.89%), perforation (50.00%), and experienced conductive hearing loss(54.54%). There was no significant difference between ETF and Eustachian tube during surgery (p = 0.439).Conclusion: This study reported that most CSOM patient had total impaired ETF with open Eustachiantube.
Evaluated Stress and Anxiety in College Students before and After Midterm Exam
Authors: Rozy Kumari  , Monika Sharma
Published: March 2021

The purpose of this study is to assess anxiety and stress in college student before and after midterm exam.The study will be conducted on N=200 students of Galgotias University, Greater Noida, U.P., India. Scaleis taken as outcome measure and students are asked to fill a form (according to DASS and PSS) after takingconsent before and after midterm examination. There collected data is then to be compared to know theeffect of exams on stress and anxiety level of students.Background: The spiritual well-being of university student is an area of amplify reflection universal. Theaim of this student is to check-up the expansion of stress and concern into a group of Galgotias universitystudent. Solely as each young person, undergraduate students needfulness to cope.Method: We are taking 200 subjects for this study. My study is based on observational study. We are usingDASS and PSS scale for measuring the stress and anxiety of the students. Inclusion criteria is stress andanxiety in college student during midterm exam and exclusion criteria is neurological and psychologicaldisorders.Results: We are hoping for positive result. We would find that the students take exam stress and anxietylevel increase.Discussion AND Conclusion: We would conclude positive result of our study. Our study will show thatduring and before exam students face stress and anxiety and after exam it will decrease.
Rate of Hypokalemia and Risk Factors in Patients on Peritoneal Dialysis Under PD First Policy
Authors: Sajja Tatiyanupanwong  , Wongsa Laohasiriwong  , Nathaphob Chaichaya  , Bandit Thinkhamrop  , Pokkrong Limpwanta  , Jadsada Thinkhamrop  , Siribha Changsirikulchai
Published: March 2021

Background: Hypokalemia is common among peritoneal dialysis (PD) patients. The incidence rate ofhypokalemia and risk factors were investigated.Material and Method: A retrospective cohort, enrolled 1,044 incident PD patients under the Universal HealthCoverage(UHC) Scheme of a regional hospital between January 2012 and December 2018. Hypokalemiawas defined as having serum potassium less than 3.5mEq/L. The rate of hypokalemia in episodes per oneyear at risk was determined. Risk factors of hypokalemia were reported as an incidence rate ratio usingPoisson regression.Results: The incidence rate of hypokalemia was 2.21(95% confidence interval, 2.14-2.27)episodes per oneyear at risk. Risk factors of hypokalemia were ; older than 60 years, female, diabetes, bodyweight less than45 kg, serum albumin less than 3.5 g/dL, serum phosphate less than 2.5 mg/dL, and total lymphocyte countless than 1,500 cells/mm3.Conclusions: Hypokalemia was frequently occurred in PD patients. Elderly PD patients, female, diabetes,malnutrition, low serum albumin, and lowserum phosphate had higher risks to develop hypokalemia.
The Relationship of Adding Allicin Powder to Diet on Concentration of Glutathione Enzyme and Histological of Thymus Gland of Broiler
Authors: Salman K.A.A  , Al-Mashhadani H.A.  , Al-Hayani W.KH
Published: March 2021

This study was conducted at the field of poultry - Abu Gharib/department of Animal Production/college ofagricultural engineering Sciences - university of Baghdad, during the period from 12/10/2019 to 24/11/2019duration (42 days), to demonstrate the effect of adding different levels of Allicin to broiler diet on Glutathionelevel in blood and histological of thymus gland, total of 225 Ross 308 chicks was used. Birds were randomlydistributed into five treatment groups which were : First treatment T1: without additives to diet (control),other treatments T2, T3, T4, T5 was added Allicin at a rate of (800,600,400,200 mg/Kg diet) respectively,and Allicin was added from first day until the end of the experiment for all addition treatments, results of thisexperiment showed: High significant (P<0.01) in all additive treatments compared to control for glutathioneenzyme in plasma at 21, 42 days for broiler age. With respect to the histological examination of thymusgland showed that adrenocortical hyper function and degeneration and depletion in lymphoid tissue in T2,T3 and T5 treatments compared to control treatment, while cortex and Pulp with a lymphatic interstitial inthe stage of degeneration for T4 and control treatments.
Assessment of Potential Factors that Effect Women Response to Labor Pain at Al-Elwyia Maternity Teaching Hospital
Authors: Sarab Nasr Fadhil  , Rabea Mohsen Ali  , Aqdas Dawood Salman
Published: March 2021

This study aims to assess the potential factors that effect on women response to labor pain. A descriptivedesign was conducted on non-probability (Purposive Sample) of (60) pregnant women admitted to AlElwyia Maternity Teaching Hospital suffering from labor pain. The data were analyses used descriptive &inferential statistical. The study results show a highly significant differences concerning factors aggravatelabor pain regarding positive and negatives items generally, and there source factors have highly assessedcompletely as very enough which accounted (94%), and service provider factors also extremely assessedgood. The study concluded that there are many factors effect on women’s coping with labor pain. The studyrecommended developing educational program for pregnant women teach them about all changes duringperiod of pregnancy and labor, and initiation of childbirth classes in primary health care centers
Role of Intestinal Microbiota and its Virulence Factors in Pathogenesis of Inflammatory Bowel Disease
Authors: Sarah S. Abdul-Hussein  , Neihaya H. Zaki  , Ali H. Ad’hiah
Published: March 2021

Inflammatory bowel disease (IBD) is a chronic relapsing unexplained etiological condition and microbiotahave been suggested to influence its etiology and pathogenesis. Ulcerative colitis (UC) and Crohn’s disease(CD) are the two main categories of this disease. The present study examined the fifty fecal samples obtainedfrom IBD patients and control. The bacterial isolates were identified by culture, microscope examination,biochemical test, and Vitek 2 compact system.Results showed that IBD patients havedifferent percentages ofProteobacteria (54.5%), Actinobacteria (1.6%), and Firmicutes (43.8%) when identified. They encompassed17 genera that involve 121 bacterial isolates. The corresponding percentages in control were 49%, 0%and 51%, respectively, with four genera and 68 bacterial isolates. The bacterial isolates of IBD patientsand control are assessed for some virulence factors, which included biofilm formation and production ofphospholipase and hemolysin, as well as antibiotic susceptibility. In IBD patients, evaluation of biofilmformation revealed that 20.6% of isolates were high-producing, 69.4% was moderate producing and10%non-biofilm producing. The corresponding percentages in control were 1%, 62% and 37%, respectively.The bacterial isolates showed different abilities in producing phospholipase. In samples of patients, 20.5%of isolates showed large activity, 44% moderate activity and 35.5% negative activity. For control samples,most of the isolates were non-producer of phospholipase (66%), while large and moderate enzyme activityaccounted for 4.5% and 29.5%, respectively. The hemolysin enzyme activity was determined as 35% ofisolates with high activity, 40% with moderate activity and 25% without activity. These percentages incontrol isolates were 25%, 35% and 40%, respectively. Imipenem was the most effective antibiotic againstgram-positive and gram-negative bacteria of the patient isolates with the resistance of 27% and 24%respectively, while the less effective antibiotics was cefixime with resistance of 95% and 88%, respectively.In the control isolates, the imipenem was also the most effective against bacteria with a resistance of 15%.The less effective antibiotics for gram-positive isolates was erythromycin with resistance of 43%and forgram-negative isolates, it was tetracycline was (45%).
Death by Stimulation of the Left Vagus Nerve in a Case of Neck Grasping in a Healthy Young Man
Authors: Saverio Potenza  , Alessandro Mauro Tavone  , Claudia Scipione  , Giovanni Arcudi  , Gian Luca Marella
Published: March 2021

Fatal neck pressure due to manual strangulation is a relatively common event. Sudden deaths that occur inthe first seconds of pressure are attributed to effects of the nerve. According to leading authors, the processoccurs through a reflex arc where the afferent (sensory) nerve impulses emerge in the carotid complex of thenerve endings, but not in the vagus trunk itself.On the contrary, we describe one such fatality. The body of a man in his early twenties came to attention inour Institute. According to testimonies and investigations, the victim had a domestic fight with his brother.After a verbal altercation, the victim was grabbed by the neck and immediately fell dead. During the externalexamination, only two small finger-nail superficial abrasions were found in the left cervical region. No othersigns of violence were detected. The dissection of the neck only revealed a perineural hematoma in theleft vagus trunk in the cervical tract. The cause of death was attributed to neurally mediated cardiac arrestinduced by direct left vagus nerve compression.
Issues Arising from the Creation of Special Economic Zone in Southern Thailand: A Scoping Step of Rapid Health Impact Assessment
Authors: Suvapak Benjatanawat  , Sang-arun Isaramalai  , Dudsadee Muenhor  , Pongthep Sutheravut
Published: March 2021

Background: Special Economic Zone (SEZ) policy of Thai government aimed to promote the economyin bordered provinces. Its establishment may cause concerns and impacts on communities. This articleexplores those issues arising from SEZ establishment in Southern Thailand.Method: The scoping step of rapid health impact assessment process was applied using documentaryresearch combined with qualitative descriptive approaches, including focus group discussions, interviews,and brainstorming. Data were collected from seventy participants, comprising government officials, localgovernment officials, community leaders, public health volunteers, members of local organizations, andlocal residents. Content analysis was used to analyze the data.Conclusion: The most important issues were found in four aspects—economic, social, environmental, andhealth. The economic aspect involved higher income and more employment opportunities, while for theenvironmental aspect, the issues were related to waste management and water pollution. The social issuescomprised the build-up of traffic and the influx of migrant workers. The health issues were emerging/reemerging infectious diseases, particularly from migrant workers and the insufficiency of health services. Asa result, a rapid health impact assessment should be carried out based on these issues. It should be taken intoconsideration by local officials responsible for developing and regulating the SEZ.
Phenolic Profile and Antioksidant Activity of Trigona Honey in Bone, South Sulawesi, Indonesia
Authors: Tri Damayanty Syamsul  , Rosdiana Natzir  , Suryani As’ad  , Veni Hadju  , Hasyim kasim  , Andi Tenriola  , Wahyuni
Published: March 2021

Introduction: Stingless bee honey has different characteristics from other types of bee honey in termsof colors, tastes, water content, and sugar. Trigona honey is one of the local products in South Sulawesiproduced by stingless bees from Tetragonula species widely known to the public. This study determined thephenol content of trigona honey and its antioxidant activity.Method: The compounds of trigona honey ethanol extract were identified using gas chromatography. Theantioxidant activity of the extract was examined with the DPPH method.Result Content test shows that trigona honey has bioactive compounds, flavonoids, alkaloids, andtriterpenoids. DPPH show to trigona honey 104,25.Conclusion: Trigona honey contains mild antioxidant activity and metabolite compounds such aspolyphenols, flavonoids, alkaloids, and triterpenoids. The nutrient activity can reduce blood glucose andincrease insulin plasma.
QTc Interval Prolongation in Drug Resistant-Tuberculosis Patients Treated with Shorter Treatment Regimen
Authors: Tutik Kusmiati  , Yulia Devina Suci  , Soedarsono
Published: March 2021

Background: Shorter Treatment Regimen (STR) is a combination of treatments with a shortened periodfrom 20-24 months to 9-11 months. Shortened treatment requires a higher dose of drug to kill resistantbacteria. Corrected QT (QTc) interval prolongation is one of the severe side effects of treatment.Objective: This study aimed to find the factors of QTc prolongation in Drug Resistant-Tuberculosis (DRTB) patients treated with STR during an intensive phase.Method: An analytical retrospective study was conducted at Dr. Soetomo General Academic Hospital,Surabaya, Indonesia. DR-TB patients on the STR regimen were collected based on medical records betweenSeptember 2017 to August 2018. QTc interval was calculated by Fredericia formula. The relationshipbetween QTc interval at baseline and occurrence of QTc prolongation was analyzed using Chi-Square offisher’s exact test.Results: Among 108 patients on the STR regimen, there were 20 (28%) patients experienced moderateQTc prolongation (471-500 ms), and 31 (28%) patients had severe QTc prolongation (>500 ms) during fourmonths observation period in STR treatment. The prolonged QTc interval was significantly related to QTcinterval at baseline (p = 0.001). The QTc interval at baseline correlated significantly with the start time ofQTc prolongation (p < 0.001). Risk factors of age, gender, comorbid, hypertension, and potassium level atbaseline had a significant negative correlation to QTc prolongation.Conclusion: The prolonged QTc interval was significantly related to QTc interval at baseline. The QTcinterval at baseline correlates significantly with the start time of QTc prolongation.
Screening of Thyroid Function Test During First Trimester of Pregnancy
Authors: Vanaraj Diyora
Published: March 2021

Introduction: During pregnancy maternal thyroid dysfunction has been associated with a number of adverseoutcomes, like preterm birth, placental abruption, fetal death and impaired neurological development inthe child. The presence of Thyroid Peroxidase Antibody (TPO-Ab) results miscarriage, preterm birth andmaternal post-partum thyroid disease. Hypothyroidism is closely associated with the presence of ThyroidPeroxidase Antibody. If a pregnant woman is positive for TPO-Ab in early pregnancy, her chances todeveloping thyroid abnormalities.Objective: To find out the level of TPO-Ab and thyroid status in first trimester of pregnancy. Method:Observational cross-sectional Study was designed in Department of Biochemistry, Medical college,Vadodara, Gujarat, India.Sample Size: 200 Normal pregnant women that randomly selected from the first trimesters of pregnancy.The study parameters were - thyroid peroxidase anti-body (TPO-Ab); serum thyroid stimulating hormone(TSH); serum T3 and serum T4.Result: Our study found that 30(15%) pregnant women of first trimester was hypothyroidism (TSH>2.5mIU/l) Out of these 30 females, 9(4.5%) had overt hypothyroidism & 21 (10.5%) had subclinicalhypothyroidism, among these 30 subjects, 26(13%) had found TPO-Ab positive (TPO-Ab >35 IU//mL)there was a significant positive correlation between positive TPO-Ab and serum TSH level of study subjectsand there was a negative correlation between serum TSH and serum T4,T3 level in study subjects.Conclusion: In this study we found 15% prevalence of hypothyroidism (4.5 % overt & 10.5 % subclinical)in first trimester of pregnancy. We found positive TPO-Ab in 13% of pregnant females and all these hadsome thyroid dysfunctions, subclinical or overt hypothyroidism, subclinical being much more common thanovert hypothyroidism.
Utilization Review of Imaging Equipment: An insight into CT Scanning
Authors: Vijay Kumar Tadia  , Shakti Kumar Gupta  , Sidhartha Satpathy  , Arun Kumar Gupta  , Sanjay Kumar Arya
Published: March 2021

Introduction: Radio diagnosis service plays a crucial role in diagnosis of the patient’s disease. The volumeof patients utilising this service is very high. This service also takes away the sizeable share of total capitalinvestment and therefore, the optimal utilization of this service becomes important.Methodology: Literature review was done through Google scholar, electronic database of PubMed andother relevant databases. The query terms like Utilization Review of Imaging Equipment, Utilisation of CTScanners, Capacity of Scanners in Radiology and Waiting Times for Imaging were used to fetch the relevantdata sources. Around 130 articles were reviewed and analysed.Results: The number of CT Scans per 1 million of population in High Income (HI), Upper Middle Income(UMI), Lower Middle Income (LMI) are 14.7, 7.3, 3.7. The CT scanners are one of the most expensivepieces of medical equipment in hospitals, with CT scanners costing between $1 million (?7 crore) and $2million (?14 crore).There is a substantial variation in the utilisation of these services, including number of scans per day andwait times. Increasing the scanner efficiency and utilisationcan significantly decrease the cost per scan andincrease access to imaging services.Expanding capacity, improving operating procedures by reducing change-over times, and improvingcapacity allocation in combination with scheduling procedures can contribute to the overall reduction of CTaccess time.Discussion and Conclusion: By acquiring Utilization data about CT Scanners, we get to know a completeand accurate overview of how Scanners are used. The CT scanner utilisation can be improved in both publicand private health sector by analysingthe key information about the utilisation of their own and other healthservices’ CT scanners.
World War 1 Antiseptic Working Miraculously in Complicated Wounds
Authors: Vipul Gurjar  , Viraj Narola  , Bhavin Shah
Published: March 2021

Introduction: Diabetic foot and complicated ulcers are relatively common occurrence in daily surgical topatient department for managing them various dressing materials and solutions are available. One of suchis acriflavine emulsion.Case Presentation: Both patients were diabetic having large ulcers over leg 2nd was Hepatitis B positivealso having large leg ulcer due to insect bite. In both Acriflavine emulsion was used as dressing material.STSG was performed in both and graft were accepted with uneventful post op courseDiscussion: Acriflavine made from acridine has a local antiseptic property with Antimicrobial and antiviralaction it does have a skin irritant 1 property but to neutralise that glycerine was used in 1:1000 emulsionConclusion: Acriflavine which was used in world war1 as antiseptic solution for war wounds can be usedfor dressing of complicated ulcers and wounds to gainbetter results.
The Relationship between Preeclampsia with the Occurrence of Postpartum Depression in Masyita Delivery Hospital Makassar, Indonesia
Authors: Wa Mina La Isa  , Ernawati  , Amriati M.  , Rusni M.  , Sitti Nurbaya  , M. Askar
Published: March 2021

Preeclampsia in Indonesia remains a huge problem during pregnancy with high morbidity and mortality.Many risk factors influence the occurrence of preeclampsia, such as the family history of preeclampsia,kidney disease, diabetes mellitus, chronic hypertension that has been suffered previously by pregnant mothersbefore pregnancy (preeclampsia superimposed), obesity, and postpartum depression. The research objectivewas to determine the relationship between preeclampsia and the occurrence of postpartum depression inMasyita Delivery Hospital Makassar. This study used quantitative research method with a cross-sectionaldesign. Sampling using purposive sampling with a sample size of 61 postpartum mothers. Collecting datausing a questionnaire and analyzed using the Chi-Square test. This study found that pregnant mothers whoexperienced mild preeclampsia were 34 subjects with 8.8% of them had postpartum depression, severepreeclampsia experienced by 7 subjects with 71,4% of them had postpartum depression. The results ofstatistical tests using Chi-square obtained the p-value=0.001. This study concluded that there is a significantrelationship between preeclampsia and the incidence of postpartum depression in Masyita Delivery HospitalMakassar, Indonesia.
Assessment of Pentraxin 3 (PTX3) and Sclerostin (SOST) Levels in Serum of Patients with Chronic Kidney Disease
Authors: Wijdan Rajh Hamza Al-Kraity
Published: March 2021

In the present study, 70 of patients were 35 males and 35 females were suffering from chronic kidneydisease, and 20 of control group. The samples were collected from Specialized Center for Diseases andKidney Transplant in AL-Sadder Medical City/Najaf Governorate/Iraq, during the period from July tillAugust, 2019. The ages of control and patients ranged 30 to 69 y old. The patients group was divided intosubgroup according to the age and gender, Patients without a complete medical record were excluded andthose with other diseases were excluded.The present study revealed a significant enhance (p<0.05) inserum PTX3 and SOST levels in CKD comparewith control group, while a significant decline (P<0.05) in serum HDL level of CKD in comparison withcontrol group. The result indicated no significant differences (p>0.05) in serum of PTX3 and SOST levelsbetween female and males groups of CLD patients. Also, The results showed a significant increase (p>0.05)in serum PTX3 and SOST levels there was a significant increase(p<0.05)among different groups ages. Thereis a positive association between PTX3 and SOST concentrations of CKD patientsConclusion: The current study conducted that PTX3 and SOST levels were good markers for diagnosis anddetection of chronic kidney disease in both genders the males and females.