bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on Intelligent Estimation Method of Human Moving Target Pose Based on Adaptive Attention Mechanism
Authors: Ding Meishuang , Zhao Jing
Published: February 2022

In daily physical education, posture performance is an important basis for making excellent results. This paper explores an intelligent method to estimate the target pose based on adaptive attention mechanism. First, the regional attention is iteratively generated from a global level to a local level based on the attention mechanism. Human decision-making patterns are imitated to evaluate the effectiveness of regional attention in real time. The level of attention mechanism is adaptively adjusted and focused layer by layer to achieve precise target detection and tracking. Second, with the target frame obtained from each frame, the pose estimation algorithm finds the key points of human body, enabling the human body pose optimization strategy to solve the crossover problem of the key points. Results of experiments on sports video images show that the proposed method has a higher accuracy in pose estimation than other algorithms and can help sportsmen adjust their training methods scientifically.
Reliability Analysis of a Two Nonidentical Unit Parallel System with Optional Vacations under Poisson Shocks
Authors: El-Sherbeny Mohamed S. , Hussien Zienab M.
Published: February 2022

In this article, we study the impact of some system parameters on an industrial system consisting of two nonidentical parallel units with one repairer. The active unit may fail due to essential factors such as aging or deterioration, or due to external phenomena such as Poisson shocks occurring at different time periods. Whenever the value of a shock is greater than the specified threshold of the active unit, the active unit fails. The article assumes that the repairman can make one of two decisions at the beginning of system operation: either he takes a vacation when the two units are operating normally, or he remains in the system to monitor it until the first failure of the system. If a failure occurs in either unit during the repairman’s absence, the failed unit must wait until the repairman is called back to work. We assume that the value of each shock is i.i.d. with a known distribution. The length of the repairman’s vacation, the repair time, and the recall time are arbitrary distributions. Various reliability measures were calculated using the supplementary variable technique and the theory of Markov vector processes. Sensitivity and relative sensitivity analyses were also performed for the system parameters. Finally, numerical calculations and graphical analyses were performed to validate the derived indices.
A Retrospective Study of Incidence and Predictors on Mother-to-Child Transmission of HIV among HIV-Exposed Infants in West Guji Zone, Southern Ethiopia
Authors: Degavi Girish , Safayi Boko Loka , Adola Shiferaw Gelchu , Demisse Biniyam , Utura Takala , Gemeda Udessa , Kelna Edwin Sarah Ezhil , Demissie Fitsum
Published: February 2022

Background. The transmission of HIV from mother to child among HIV-positive infants is estimated to be higher than 20%, despite the fact that antiretroviral treatment is available for antenatal mothers with HIV. In Ethiopia, the prevalence of HIV transmission from mother to child among infants aged one and a half years is estimated to be approximately 15.7 percent. Methods. A retrospective cohort analysis using a simple random sampling technique was incorporated among 422 HIV-exposed babies and their mothers who were randomly chosen and screened using OPD (outpatient card) from March 2019 to March 2021 in the general hospitals of West Guji zone, Oromia, Ethiopia. The data were coded and entered into EpiData version 4.6.1 and exported to SPSS version 23 for cleaning and analysis. Result. The study revealed that at the end of follow-up, 3.8% of the HIV-exposed infants were found to be HIV positive. Poor adherence of infant for CPT (AOR: 5.6; 95% CI: 1.010–27.24), father not enrolled to ART (AOR: 4.4; 95% CI: 1.187–15.724), age of infants at enrollment >6 weeks (AOR: 4.5; 95% CI: 1.102–16.1), mother’s enrollment to PMTCT during labor and delivery or after (AOR: 6.84; 95% CI: 1.316–42.743), and mothers on the WHO clinical stage mild or advanced (AOR: 3.6; 95% CI: 1.146–16.842) was found to be the most important significant predictors of mother-to-child transmission of HIV. Conclusion. Several factors included in the study were the main predictors of mother-to-child transmission of HIV. The study concluded that there are some lacunae in the prevention of MTCT of HIV but that the incidence of MTCT of HIV was significantly lower in this part of the world.
Delayed Epistaxis which Was Developed after Orthognathic Surgery with Le Fort I Osteotomy and Managed by Endoscopic Cauterization
Authors: Kurasawa Yuya , Sato Hitoshi , Katada Ryogo , Inada Takanobu , Shirota Tatsuo , Shimane Toshikazu
Published: February 2022

A case of delayed epistaxis from the mucosa behind the right side of the inferior nasal mucosa 11 days after orthognathic surgery by Le Fort I osteotomy is presented. The patient was a 31-year-old man who underwent orthognathic surgery under general anesthesia. No abnormal findings were found during or after the operation. The patient was discharged from the hospital 10 days postoperatively. However, bleeding from the right nasal cavity occurred suddenly on the night after discharge, and he presented to our hospital again. The epistaxis was stopped once by nasal packing containing 0.001% epinephrine and systemic infusion of carbazochrome sulfonic acid and tranexamic acid. However, when the nasal packing was removed the next day, right nasal epistaxis was observed again. Curvature of the nasal septum and thickening of the inferior turbinate mucosa were seen on inspection; although, no active bleeding point was identified. Decreased nasal mucosa thickening and bleeding were observed after nasal packing containing 0.02% epinephrine. When the inside of the nasal cavity was observed endoscopically, an approximately 2 mm laceration was found in the mucosa behind the side wall of the right inferior nasal mucosa, and bleeding from the same part was confirmed. After endoscopic cauterization for hemostasis of the nasal mucosa, no rebleeding was observed. Although delayed epistaxis after Le Fort I osteotomy are often performed CT angiography to confirm the bleeding site, endoscopic cauterization would be primarily useful because of less invasiveness.
Analysis of Cybersecurities within Industrial Control Systems Using Interval-Valued Complex Spherical Fuzzy Information
Authors: Alothaim Abdulrahman , Hussain Shoukat , Al-Hadhrami Suheer
Published: February 2022

Technology affects almost every aspect of life and is constantly changing. Digital communication technology has made it easier and faster to connect people all over the world. Digital technology is used in varies fields, including business, industries, companies, and educational institutions. There are various benefits of technology; it is also associated with a number of risks and dangerous threats known as cybercrimes. Cybercrime is a criminal activity that targets digital technology, like a computer, a computer network, or a mobile device. Cybersecurity is the way we reduce the risk of becoming a victim of cybercrime. Cybersecurity is the process of defending against cyberattacks. By using these concepts, we investigated the interval-valued complex T-spherical fuzzy relations (IVCT-spherical-FRs) introduced in this paper. We studied the relationships between different types of cybersecurity and the sources of cyberattacks. Furthermore, the Hasse diagram for the interval-valued complex T-spherical partial order set and relation is developed. The concepts of Hasse diagram are being used to examine various cybersecurity techniques and practices. The most effective method is identified using the features of Hasse diagrams. Finally, comparison tests are used to demonstrate the benefits of the proposed methods.
Fuzzy Support Tensor Product Adaptive Image Classification for the Internet of Things
Authors: Shi Zhongrong , Ma Yun , Fu Maosheng
Published: February 2022

Computer vision is one of the hottest research directions in artificial intelligence at present, and its research goal is to give computers the ability to perceive and cognize their surroundings from a single image. Image recognition is an important research direction in the field of computer vision, which has important research significance and application value in industrial applications such as video surveillance, biometric identification, unmanned vehicles, human-computer interaction, and medical image recognition. In this article, we propose an end-to-end, pixel-to-pixel IoT-oriented fuzzy support tensor product adaptive image classification method. Considering the problem that traditional support tensor product classification methods are difficult to directly produce pixel-to-pixel classification results, the research is based on the idea of inverse convolution network design, which directly outputs dense pixel-by-pixel classification results for images to be classified of arbitrary size to achieve true end-to-end and pixel-to-pixel high-score image classification and improve the efficiency of support tensor product models for high-score image classification on a pixel-by-pixel basis. Moreover, considering that network supervised classification training using deep learning requires a large amount of labeled data as true values and obtaining a large number of labeled data sources is a difficult problem in the field of image classification, this article proposes using a large amount of unlabeled high-resolution remote sensing images for learning generic structured features through unsupervised to assist the labeled high-resolution remote sensing images for better-supervised feature extraction and classification training. By finding a balance between generic structural feature learning of images and differentiated feature learning related to the target class, the dependence of supervised classification on the number of labeled samples is reduced, and the network robustness of the support tensor product algorithm is improved under a small number of labeled training samples.
Neuroprotective Effect of Acupuncture against Single Prolonged Stress-Induced Memory Impairments and Inflammation in Rat Brain via Modulation of Brain-Derived Neurotrophic Factor Expression
Authors: Lee Bombi
Published: February 2022

Posttraumatic stress disorder (PTSD) is a serious mental disorder that can appear after exposure to extreme stress. Acupuncture is an alternative therapy that is widely used to treat various neurodegenerative diseases, as well as cognitive and memory impairments. The aim of this study was to examine whether acupuncture stimulation at a specific acupoint (Shenmen or heart meridian, HT7) could improve memory defects caused by single prolonged stress (SPS) in rats. After exposure to SPS, acupuncture on the HT7 acupoint in male rats was performed, once daily for 21 days. We confirmed that this treatment improved fear memory, cognitive function, and spatial memory by modulating the neuroinflammation and expression of brain-derived neurotrophic factor (BDNF) mRNA in the brain. It also significantly inhibited the activation of proinflammatory cytokines, such as tumor necrosis factor-α and interleukin-1β and the enzyme cyclooxygenase-2 in the brain; it increased the expression of BDNF mRNA in the hippocampus. Our findings provide valuable information concerning the clinical usefulness of acupuncture in the treatment of PTSD.
Stereotactic Radiosurgery (SRS) Induced Higher-Grade Transformation of a Benign Meningioma into Atypical Meningioma
Authors: Basalamah Ali , Al-bolbol Mohammed , Ahmed Osman , Ali Nagoud , Al-Rashed Sabah
Published: February 2022

Background. Stereotactic radiosurgery (SRS) is a widely used treatment modality for the management of meningioma. Whether used as a primary, adjuvant, or salvage procedure, SRS is a safe, less invasive, and effective modality of treatment as microsurgery. The transformation of a meningioma following radiosurgery raises a concern, and our current understanding about it is extremely limited. Only a few case reports have described meningioma dedifferentiation after SRS to a higher grade. Moreover, a relatively small number of cases have been reported in large retrospective studies with little elaboration. Case Description. We report a detailed case description of a 41-year-old man with progressive meningioma enlargement and rapid grade progression after SRS, which was histopathologically confirmed before and after SRS. We discussed the clinical presentation, radiological/histopathological features, and outcome. We also reviewed previous studies that reported the outcome and follow-up of patients diagnosed with grade I meningioma histopathologically or presumed with benign meningioma by radiological features who underwent primary or adjuvant radiosurgery. Conclusion. The risk of progression after SRS is low, and the risk of higher-grade transformation after SRS is trivial. The early timing for recurrence and field-related radiation may favor a relationship between SRS and higher-grade transformation (causality) although transformation as a part of the natural history of the disease cannot be fully excluded. Tumor progression (treatment failure) after SRS may demonstrate a transformation, and careful, close, and long follow-up is highly recommended. Also, acknowledging that there is a low risk of early and delayed complications and a trivial risk of transformation should not preclude its use as SRS affords a high level of safety and efficiency.
Dose-Response Associations of Metabolic Score for Insulin Resistance Index with Nonalcoholic Fatty Liver Disease among a Nonobese Chinese Population: Retrospective Evidence from a Population-Based Cohort Study
Authors: Cai Xintian , Gao Jing , Hu Junli , Wen Wen , Zhu Qing , Wang Mengru , Liu Shasha , Hong Jing , Wu Ting , Yang Shunfan , Tuerxun Guzailinuer , Li Nanfang
Published: February 2022

Purpose. This study is aimed at investigating the association between the metabolic score for insulin resistance (METS-IR) index and nonalcoholic fatty liver disease (NAFLD) in the nonobese population and its predictive value. Methods. 10730 nonobese subjects were selected from longitudinal cohort research conducted from January 2010 to December 2014. Cox proportional hazards models were employed to assess the relationship between METS-IR and new-onset NAFLD. Generalized additive models were used to identify nonlinear relationships. In addition, we performed subgroup analyses and interaction tests. The time-dependent receiver operating curve (ROC) and area under the ROC (AUC) were utilized to measure the discriminatory ability of METS-IR for new-onset NAFLD. Beyond clinical risk factors, the incremental predictive value of METS-IR was appraised using integrated discrimination improvement (IDI), C-index, and net reclassification index (NRI). Results. Over a median period of 804.50 days of follow-up, 1859 (17.33%) participants had a new onset of NAFLD. After adjusting for confounders, the HR for new-onset NAFLD in the Q4 group was 6.40 compared with the Q1 group. When METS-IR was considered a continuous variable, the risk of NAFLD increased by 34% for every 1 SD increase in METS-IR. The smoothing curve shows the dose-response relationship between METS-IR and the presence of new-onset NAFLD. Using a two-piecewise linear regression model, we derived a METS-IR inflection point of 36. HRs were 1.31 on the left side of the inflection point and 1.04 on the right side of the inflection point (log-likelihood ratio test,P<0.001). Subgroup analyses and interaction tests revealed an interaction between gender and SBP in the association between METS-IR and new-onset NAFLD. In the subgroup analysis of gender and SBP, we observed a higher risk of new-onset NAFLD in men and in those with abnormal SBP levels. We evaluated the ability of METS-IR to identify new-onset NAFLD at different time points. The AUCs at 1, 2, 3, and 4 years were 0.784, 0.756, 0.758, and 0.752, respectively, which represent good discrimination of new-onset NAFLD. The addition of METS-IR greatly improved the reclassification and differentiation of clinical risk factors, with an NRI of 0.276 and an IDI of 0.068. In addition, the addition of METS-IR increased the C-index from 0.719 to 0.771. Conclusion. In a nonobese Chinese population, elevated METS-IR was independently associated with an enhanced risk of NAFLD development and a dose-response relationship existed. In addition, METS-IR might be a reliable indicator for screening individuals at risk for early NAFLD, especially in nonobese populations.
Controllable Clustering Algorithm for Associated Real-Time Streaming Big Data Based on Multi-Source Data Fusion
Authors: Cui Haiting , Li Shanshan
Published: February 2022

Aiming at the problems of poor security and clustering accuracy in current data clustering algorithms, a controllable clustering algorithm for real-time streaming big data based on multi-source data fusion is proposed. The FIR filter structure model is used to suppress network interference, and ant colony algorithm is used to detect the abnormal data in the big data. By optimizing the iteration, the pheromone concentration is placed in the front position as the abnormal data point, and the filter is introduced. The fusion scope of multi-source data fusion is set. Combined with the data similarity function, the multi-source data fusion concept is used to construct the associated real-time streaming big data fusion device, and the data deduplication results are substituted into the fusion device to obtain the data clustering result. The experiments show that the proposed algorithm has high safety factor, good data clustering accuracy, high clustering efficiency, and low energy consumption.
Milk Fatty Acid Profile of Holstein Cows When Changed from a Mixed System to a Confinement System or Mixed System with Overnight Grazing
Authors: Grille Lucía , Adrien María L. , Méndez María N. , Chilibroste Pablo , Olazabal Laura , Damián Juan P.
Published: February 2022

This study is aimed at comparing the milk fatty acid profile (FAP) of cows that changed from a mixed system (MS) of double grazing plus total mixed ration (TMR) to a total confinement system (TCS, 100% TMR) with cows that changed to another MS with one overnight grazing plus TMR and compare with cows that were kept unchanged in TCS. The diet change was made in the second month of lactation. The milk samples were collected at one (M1-spring) and three months of lactation (M3-summer). Three treatments are as follows (each

n
=
10

): confined cows fed with TMR throughout the period (GTMR), cows that changed from MS with double grazing plus TMR in M1 to TCS in M3 (GCHD), and cows that changed from a MS with double grazing plus TMR in M1 to a MS with overnight grazing plus TMR in M3 (GTMR+P). Unlike GTMR+P, GCHD improved milk production after change (increased 14% from M1 to M3), but milk FAP was impaired. In M3, conjugated linoleic acid (C18 : 2-CLA) in GTMR and GCHD was lower than GTMR+P (

p
<
0.05

), and linolenic (C18 : 3-n-3) was lower in GCHD than GTMR+P. Maintaining grazing in summer overnight sustained milk fat quality, evidenced by higher C18 : 3 (n-3); C18 : 2 (CLA); and n-6/n-3 ratio than cows that changed to TCS.
Performance Measurment and Lead-Time Reduction in EPC Project-Based Organizations: A Mathematical Modeling Approach
Authors: Ghasemi Matina , Nejad Mazyar Ghadiri , Alsaadi Naif , Abdel-Jaber Mu’tasim , Ab Yajid Mohd Shukri , Habib Mamun
Published: February 2022

To characterize the process of lead-time reduction in EPC project-based organizations, including the engineering, procurement, and construction activities, various elements such as organizational issues, firm resources, used methods and techniques, and performance measuring tools are important. In this study, the four mentioned elements are evaluated through a survey in different EPC project-based organizations. The survey is sent to only experts and managers who are involved in EPC projects, and the obtained data is used to test the relationship between the mentioned variables and the lead time of developing new products. This evaluation is followed by a set of generalized lessons learned and courses of action to improve the development process. Additionally, the attributes of performance measurement in such projects are scrutinized. Therefore, to analyze the impacts of the mentioned variables and their variations on the performance measurement, a mathematical model based on the fuzzy approach is developed. The results show that all of the four considered variables are correlated to the lead time and affect the quality perceived by the main client and the cost of the project. Moreover, data obtained from the proposed mathematical formulations illustrated that the fuzzy modeling approach is an effective method to predict the performance measurement level when the levels of the input variables are given.
Determining the Optimal Scalar Intensity Measure of Floor Communication Towers
Authors: Li Bo , Lai Qinghui , Guo Endong , Mao Chenxi , Li Xiaofei
Published: February 2022

Various structural types and ground motion characteristics lead to distinct intensity measures of structural seismic performance. For the lattice high-rise steel structure of communication towers, determining the intensity measures to adjust ground motion is critical. Additionally, a crucial problem is whether the ground motion intensity parameters of pulse-like ground motion and ordinary ground motion are consistent. In this study, a standard floor four-leg angle steeled communication tower was considered the study object, and 50 pulse-like ground motions and 50 ordinary ground motions were identified to form a pulse-like ground motion set and ordinary ground motion set, respectively. For comparative analyses, 15 ground motion parameters, including amplitude, spectrum, duration, and energy parameters, were selected. The results revealed that for the lattice towers, such as communication tower, under the action of pulse-like ground motion or ordinary ground motion, efficiency, practicability, and sufficiency should be considered. Furthermore, the most suitable intensity measure was the spectral acceleration corresponding to the natural period of the tower. This study provides a basis for selecting the ground motion for dynamic time history analysis of the lattice steel tower.
A Sparse Gating Convolutional Recurrent Network for Traffic Flow Prediction
Authors: Huang Xiaohui , Tang Jie , Peng Zhiying , Chen Zhiyi , Zeng Hui
Published: February 2022

With the continuous development of deep learning, more and more huge deep learning models are developed by researchers, which leads to an exponential increase of the parameters of models. Therein, the convolutional recurrent network as a type of widely used deep learning method is often employed to handle spatiotemporal data, e.g., traffic data. However, because of the large number of parameters in the model, the convolutional recurrent network needs to consume a lot of computing resources and time in the training process. To reduce the consumption of resources, we propose a sparse convolutional recurrent network with a sparse gating mechanism that is able to reduce the complexity of the network by an improved gate unit while keeping the performance of the model. We evaluate the performance of our proposed network on traffic flow datasets, and the experimental results show that the parameters of the model are significantly reduced under the condition of similar prediction accuracy compared with the traditional convolutional recurrent network.
A Four-miRNA-Based Diagnostic Signature for Rheumatoid Arthritis
Authors: Jiang Xu , Wei Zhenjie , Wang Chao , Wang Qianqian , Zhang Yanzhuo , Wu Chengai
Published: February 2022

Background. As a chronic inflammatory disease, rheumatoid arthritis (RA) usually leads to cartilage and bone damage, even disability. Earlier detection and diagnosis are crucial to improve the therapeutic efficacy, and the aim of our study is to identify a potential diagnostic signature for RA. Methods. We downloaded the GSE124373 dataset from the Gene Expression Omnibus (GEO) database. And differential expression analysis of miRNAs was conducted using the limma package of R language. The potential targeted mRNAs of differentially expressed miRNAs were predicted using the MiRTarBase database. The clusterProfiler package in R language was used to conduct functional enrichment analysis (GO term and KEGG pathway). Then, based on the key miRNAs screened by stepwise regression analysis, the logistic regression model was built and it was evaluated using a 5-fold cross-validation method. Results. A total of 19 differentially expressed miRNAs in the blood sample of RA patients compared with that of healthy subjects were identified. Nine optimal miRNAs were screened by using stepwise regression analysis, and four key miRNAs hsa-miR-142-5p, hsa-miR-1184, hsa-miR-1246, and hsa-miR-99b-5p were further optimized. Finally, a logistic regression model was built based on the four key miRNAs, which could reliably separate RA patients from healthy subjects. Conclusion. Our study established a logistic regression diagnostic model based on four crucial miRNAs, which could separate the sample type reliably.
An Analysis of Students’ failing in University Based on Least Square Method and a New
arctan
−
exp
Logistic Regression Function
Authors: Xianghan Zhang , Qunli Zhang
Published: February 2022

By improving the logistic regression function and selecting a step-by-step fitting result using the least square method as the input of the logistic regression model, this paper analyzes the situation of students failing the course. Compared with arctan-exp function and sigmoid function, the former has better robustness and stability and makes the results tend to 0 and 1 and be classified. An improved algorithm based on

arctan
−
exp

logistic regression and least square method, which combines the advantages of both functions, is studied. Finally, an implementation algorithm is presented to well meet the function. Besides, through a simulation example, both theoretical analysis and experimental evaluation demonstrate the effectiveness of our proposed approach, and it shows that the nonlinear arctan-exp function, which bases on the least square method, is used as the distribution function to predict the effectiveness of students’ failure. The algorithm has been compared and evaluated, which obtains superior results in terms of both accuracy rate and recall rate of the diagnosis results of the students failing.
A Rare Case of Large-Vessel Vasculitis following Checkpoint Inhibitor Therapy and Pegfilgrastim
Authors: Mort Joseph , Maheshwari Shipra , Basu Nayanika , Dillon Patrick , Brady Kevin , Bear Harry , Millard Trish
Published: February 2022

Checkpoint inhibitors (CPIs) and pegfilgrastim, a long-acting growth factor agent, are vital components of current cancer treatments. Immune-related adverse events (irAEs) such as colitis and pneumonitis are well-established toxicities associated with CPI therapy. However, large-vessel vasculitis secondary to CPI utilization is reported only in rare case reports and case series. Interestingly, large-vessel vasculitis has also been reported as a rare complication of pegfilgrastim use. We present a 59-year-old female with left stage IIA (cT2N0M0) triple-negative breast cancer receiving neoadjuvant decitabine and pembrolizumab prior to neoadjuvant chemotherapy (NAC). NAC included standard-of-care dose dense doxorubicin and cyclophosphamide (ddAC) supported with pegfilgrastim use followed by weekly carboplatin and paclitaxel. After receiving her second cycle of ddAC with pegfilgrastim, the patient reported five days of left shoulder and arm pain. Subsequent CT imaging demonstrated wall thickening and inflammatory changes surrounding the left subclavian artery, aortic arch, left carotid artery, proximal innominate arteries, and the mid internal carotid arteries and its branching vessels. These findings were extremely concerning for large-vessel vasculitis. Excluding CPI therapy and pegfilgrastim use, no additional inciting event or medication that the patient was exposed to was noted to be associated with large-vessel vasculitis. We present this case to report on this rare but severe complication from commonly utilized agents in cancer treatment. We also extend the possibility of large-vessel vasculitis development in relation to the COVID-19 vaccine due to shared ingredients found in both the vaccine and pegfilgrastim. It is important to outline the treatment used for such a complication as no standardized treatment has been established for large-vessel vasculitis caused by CPI therapy or pegfilgrastim use.
Application of Electronic Nose to Predict the Optimum Fermentation Time for Low-Country Sri Lankan Tea
Authors: Sharmilan Tharaga , Premarathne Iresha , Wanniarachchi Indika , Kumari Sandya , Wanniarachchi Dakshika
Published: February 2022

The fermentation stage is vital during the black tea manufacturing process to produce the best-quality tea. The oxidation of tea biochemical compounds results in the appearance of characteristic smell peaks during the fermentation stage. These subtle changes in tea aroma are hard to detect unless one is a trained personnel. Here for the first time, we applied e-nose to monitor the fermentation process of Sri Lankan low-country tea. In this study, detection of smell peaks during fermentation was conducted by a custom-made e-nose (Digi-Nose) with four gas sensors. Singular value decomposition (SVD) is applied to eliminate the noise and dimensionality reduction in the sensor responses observed. The prediction of the time of appearance of smell peaks was conducted with a support-vector machine (SVM). Finally, theaflavin content with time was compared to validate the optimum fermentation times observed with an e-nose.
SARS-CoV-2-Associated Multisystem Inflammatory Syndrome in a Child in Uganda: A Paediatric Experience in a Resource-Limited Setting
Authors: Piloya Thereza , Nakiyingi Lydia , Kimuli Ivan , Kayima James , Lubega Joseph , Sekabira John , Aanyu Hellen T.
Published: February 2022

SARS-CoV-2-associated Multisystem Inflammatory Syndrome in children (MIS-C) has been described in developed settings that have reported a high burden of COVID-19 cases. However, to date, there are few published cases of MIS-C that have been described in the African region. MIS-C has high morbidity and even mortality without a prompt diagnosis. We report a case of a 9-year-old girl who presented with typical clinical features of MIS-C in Uganda but had a delay in diagnosis. This case report aims to raise awareness among health providers in similar settings to improve clinical suspicion of MIS-C, facilitate prompt diagnosis and treatment, and thus improve outcomes.
Vibrations Evaluation of Functionally Graded Porous Beams in Thermal Surroundings by Generalized Differential Quadrature Method
Authors: Khakpour Mahdi , Bazargan-Lari Yousef , Zahedinejad Parham , Kazemzadeh-parsi Mohammad- Javad
Published: February 2022

This study investigates how to obtain the natural frequency of functionally graded porous beams simply supported on an elastic substrate in thermal surroundings by the theory of third-order shear deformation. Temperature constantly changes in the beam thickness direction and step with the distribution of volume fraction power law of the ingredient has been affected on the material attributes. The distribution of uniform porosity at the pass phase is examined. To achieve the equations of governing, Hamilton's principle was carried out. To discretize these equations, the generalized differential quadrature method has been used. First, the approach's convergence is shown. Comparison with the results of other articles was performed for validation. Here, the impacts of numerous factors like index of power law, heat field type, temperature difference, slenderness ratio, and porosity coefficient and elastic substrate factors of a functionally graded porous beam on the natural frequencies were studied for simple boundary conditions. In addition to displaying these parameters’ impact on the beam’s thermomechanical evaluation, the conclusions also confirm the accuracy of the numerical technique used.
Research on the Combination Technology of Cultural and Creative Industries Based on TRIZ Theory
Authors: Huang Chunxia , Cheng Wenjin
Published: February 2022

In recent years, the cultural and creative industry has become an emerging industry that countries have vigorously supported and promoted in the new economic era. This article introduces the TRIZ innovation theory into the cultural and creative industry. As an innovative problem-solving theory, TRIZ has good practicability and operability. It seeks breakthroughs on the basis of original creative thinking and provides a scientific and efficient cultural creativity. Combining specific cases, analyze the innovative principles of TRIZ theory as the origin, stimulate creative methods that generate divergent thinking, aggregate thinking, and conversion thinking, and apply them to creative mechanisms and applications in cultural advertising creativity. The whole process is guided by rational principles to lead perceptual thinking, and concrete principles drive abstract imagination, exploring the source of thinking of the essence of cultural advertising creative design. This theory and its application mechanism have become a brand new thinking method and application attempt in the field of cultural advertising creativity.
Construction of Glycolytic Regulator Gene Signature to Predict the Prognosis and Tumor Immune Cell Infiltration Levels for Prostate Cancer
Authors: Zhang Ling , Wang Bin , Wang Zhi-Shun , Guo Yong-Lian , Shen Hao
Published: February 2022

Prostate cancer (PCa) is the commonly generated noncutaneous neoplasm among men worldwide. Glycolysis had been validated to promote cancer progression. However, the clinical significance of glycolytic regulators in PCa was not well understood. Here, we discovered that glycolytic regulators were dysregulated in PCa samples using GSE8511, GSE6919, and GEPIA. By detecting the expression of these regulators in PCa samples, we found that SLC2A1, SLC2A3, HK2, PFKFB2, TPI1, PKM2, and LDHA had higher expression in PCa compared with normal tissues. Moreover, both higher expression of TPI1, ALDOA, ENO1, LDHA, and PKM and lower expression of LDHB and HK2 were significantly related to shorter progression-free survival time in PCa. Of note, an 8 gene-based risk score was further constructed and confirmed to have a good performance in predicting progression-free survival (PFS) time in PCa. The signature risk score significantly correlated with NK cell, neutrophil cell, macrophage M2 cell, and myeloid dendritic cell infiltration levels in PCa. After bioinformatics analysis, our data suggested glycolytic regulators participated in the regulation of multiple nonmetabolic biological processes, such as RNA transport, biosynthesis of antibiotics, and cell cycle. We recapitulate that the glycolytic regulator signature was a prospective indicator for prognosis and immune cell infiltration levels in PCa.
Ovarian Torsion: Presentation and Management in a Pediatric Patient
Authors: Nguyen Katie P. , Valentino William L. , Bui Duy , Milestone Honey
Published: February 2022

Background. Adnexal torsion is the fifth most common gynecologic emergency accounting for approximately 20 to 30% of ovarian surgeries in pediatric patients. Case. The patient is a ten-year-old female who presented to the emergency room for severe left lower quadrant abdominal pain. On presentation, she was hemodynamically stable with an acute abdomen. A transabdominal ultrasound showed a predominantly anechoic structure measuring up to 5.6 cm without definitive Doppler flow, concerning for a large cyst causing ovarian torsion. Gynecology was consulted, and the patient underwent a diagnostic laparoscopy, aspiration of the left ovarian cyst, and left ovarian detorsion. Pathology results were consistent with benign cystic contents. Conclusion. Appropriate diagnosis and timely surgical gynecological intervention allowed this pediatric patient to salvage and preserve ovarian function.
Analysis and Calculation of the Best Center of Mass for Supercavitating Projectile
Authors: Wei Ping , Wang Shoufa , Yan Wenrong , Yu Xin
Published: February 2022

Currently, the supercavitating projectiles mostly rely on experience or experimental results to test the shape of the projectile; however, the cost of the experiment is relatively high, and there is no specific criterion to judge whether the underwater projectile is stable. To solve the aforementioned problems, we study the motion stability and establish motion equations for supercavitating projectiles. Through theoretical analysis and simulation calculations, the optimal center of mass position is designed to optimize the motion performance of underwater supercavitating projectiles. We think this work can provide theoretical support for the optimal design of underwater supercavitating projectiles.
Impact of Post-Transplantation Hypomagnesemia on Long-Term Graft and Patient Survival after Transplantation
Authors: Isakov Ofer , Patibandla Bhanu K. , Christopher Kenneth B. , Chandraker Anil , Hod Tammy
Published: February 2022

Background: Post-transplant hypomagnesemia is commonly observed among patients prescribed calcineurin inhibitor (CNIs). Methods: We conducted a retrospective single-center analysis (2000–2013, N = 726) to examine the association of hypomagnesemia with long-term patient and allograft outcomes in kidney transplant recipients. A median serum magnesium (Mg) level of all measured Mg levels from 1 month to 1 year posttransplant was calculated. Results: For every increase in Mg of 0.1 mg/dL, the risk for either graft loss or death, overall mortality, and death with a functioning graft increased by 11%, 14%, and 12%, respectively (p < 0.01). In a multivariate model, patients with median Mg level ≥1.7 mg/dL had a reduced overall survival rate (HR 1.57, 95% CI: 1.04–2.38, p = 0.033) compared to those with median Mg level <1.7 mg/dL. This association was observed in subgroups of patients above 60 years old, in those who had a slow graft function (SGF) and in females. Conclusions: Posttransplant hypomagnesemia is associated with better patient and allograft survival up to 10 years posttransplant. This relationship remained significant after accounting for baseline allograft function, presence of SGF and CNI trough levels.
Risk Management Concept Development of Pondok Pesantren Educational Institutions
Authors: Ekaningsih Lely Ana Ferawati , Salim Ubud , Djumahir Djumahir , Indrawati Nur Khusniyah , Djakfar Muhammad
Published: February 2022

The concept of risk management has been widely studied in terms of finance in Islamic and conventional banking, government institutions, and insurance. While research on non-financial risk management in educational institutionsis still rarely done. This article aims to propose the development of the concept of risk management for Islamic educational institutions, especially pondokpesantrenor Islamic boarding schools. This research is a qualitative research/conceptual paper by conducting theoretical and empirical studies on articles that have been published. The data is secondary data. The results of the study found that risk exists in all organizations including pondokpesantren, so it is necessary to carry out risk management. Risk must be managed appropriately and correctly because failure to manage risk has serious consequences for the organization. The risk management process in pondokpesantrenis based on the implementation of Islamic values ​​sourced from the Qur'an and Hadith. The most important contribution of this paper is to develop the concept of risk management for pondokpesantren.
Sekayam Subdistrict’s Food System Activities and Local Food Security
Authors: Purnawan Endar , Brunori Gianluca
Published: February 2022

This study analyzes Sekayam subdistrict’s local food system and local food security. Based on an analysis of local food vendor interviews, this research sheds light on the local food system based on five food groups modified from seven food groups of household dietary diversity scale measurement, according to the local condition. The stages of data analysis in this study adhered to the data analysis process modified from Neuman. The result indicates that the Sekayam subdistrict is self-sufficient in rice, vegetables, and freshwater fish but depends on other places for meat, seafood, and other foodstuffs such as cooking oil, milk, eggs, and sugar. Taken together, the research findings highlight the importance of developing some potential food sources to fulfill a community need so that Sekayam subdistrict in the future no longer depends much on other places supplied, to pursue better local self-sufficiency and better local food security. This paper strongly recommends policymakers, stakeholders, and local farmers, as well as the community, to plan and take some actions to pursue local self-sufficiency and better local food security in the future. The activity includes food production, processing and packaging, distribution and retailing, and consumption.
The Best Marketing 4.0 Brand Model in Indonesia
Authors: Ardiansyah Tedy , Zulfikar Ian , Awaloedin Dipa Teruna
Published: February 2022

The purpose of this study is to find out the best marketing 4.0 brand model in Indonesia, not just a brand that is a symbol of the current development of technology or industry 4.0. Marketing is a major part of the progress of a company, along with the development of technology, marketing becomes the main problem of survival of a company. Marketing 4.0 is the right answer in helping to solve these problems, especially in building a company brand. But how to build the right Marketing 4.0 so that the brand becomes the main breath of the company. The method used is a qualitative case study method, which describes in detail a program. The results of this study show an invention for the best Marketing 4.0 brand model in Indonesia, so it is expected to be a model for the company's progress in this 4.0 industry.
Observações cotidianas de um gato intelectual
Authors: Tamura Celia
Published: February 2022

This paper analyzes the roles of riempitivi and digressions in the Natsume Söseki's novel Wagahai wa neko de aru (l am a cat, 1906) considered a typical 19" Century novel, which the Author created basing on English literary sources, mainly Laurence Sterne's The life and opinions of Tristram Shandy, gentleman (1760-1767). The humor in the Sõseki's novel - expressed in riempitivi and digressions- creates an ironical comedy, which hide a pessimistic and nihilistic conception of life.
O genocídio armênio e seus reflexos na literatura
Authors: Pereira Deize Crespim
Published: February 2022

The history of Armenia in the 20th century is marked by a tragedy: the genocide of approximately 1,500.000 inhabitants of Turkish Armenia by the Ottoman Empire. The goal of this paper is to analyze two main consequences of the Armenian genocide in Armenian literature, namely, the transition from modern (1850-1915) to contemporary literature (1915-), and the formation of Armenian contemporary literature in Diaspora. While Armenian modern literature is largely characterized by militant engagement, aiming to instruct the popular masses so that they could fight for political and social justice and forindependence, Armenian contemporary literature produced in Diaspora deals mainly with questions concerning cultural identity of Armenian descendants that were born in Diaspora. We exemplify these trends with excerpts from texts written by two modern authors (Raffi and Daniel Varujan) and two contemporary ones (William Saroyan and Michael J. Arlen).
Dissociating the Neural Correlates of Planning and Executing Tasks with Nested Task Sets
Authors: Cookson Savannah L. , Schumacher Eric H.
Published: February 2022

Task processing (e.g., the preparation and execution of responses) and task representation (e.g., the activation and maintenance of stimulus–response and context information) are two facets of cognitive control supported by lateral frontal cortex (LFC). However, the mechanistic overlap (or distinction) between these two facets is unknown. We explored this by combining a complex task mapping with a precueing procedure. Participants made match/nonmatch judgments on pairs of stimuli during fMRI recording. Precues on each trial gave variable amounts of information to the participant in anticipation of the stimulus. Our results demonstrated that regions throughout LFC were more active at the stimulus (when responses could be executed) than at the cue (when they could only be prepared), indicating that they supported execution of the task agnostic to the specific task representation. A subset of regions in the left caudal LFC showed increased activity with more cue information at the cue and the reverse at the stimulus, suggesting their involvement in reducing uncertainty within the task representation. These results suggest that one component of task processing is preparing and executing the task according to the relevant representation, confined to left caudal LFC, whereas nonrepresentational functions that occur primarily during execution are supported by different regions throughout the rest of LFC. We further conducted an exploratory investigation of connectivity between the two groups of regions in this study and their potential relationship to the frontoparietal and cingulo-opercular networks. Regions with both patterns of activity appear to be part of the frontoparietal network.
Ingold’s Animism and European Science
Authors: Kochan Jeff
Published: February 2022

Anthropologist Tim Ingold promotes Indigenous animism as a salve for perceived failures in modern science; failures he claims also hobbled his own early work. In fact, both Ingold’s early and later work rely on modern scientific ideas and images. His turn to animism marks not an exit from the history of European science, but an entrance into, and imaginative elaboration of, distinctly Neoplatonic themes within that history. This turn marks, too, a clear but unacknowledged departure from systematic social analysis. By re-embracing social analysis, Ingold would overcome the obscurity that now hobbles his later work.
Geography in Couplets?
Authors: Hanigan Daniel R.
Published: February 2022

Greek periplography appears to have been an almost exclusively prosaic phenomenon. The single exception to this is Zenothemis (4th/3rd cent. BC) whom John Tzetzes credits with the production of an elegiac distich (SH 855 = Tz. H. 7.765f.) apparently sourced from a Periplous. This brief note contributes to the discussion about the shape of Zenothemis’ Periplous by offering a series of stylistic observations about the single surviving fragment and considering the rationale for ascribing (or not) seven other testimonia (SH 856-862) to this poem.
The Mystery Cults and the Latin Historians
Authors: Levene David
Published: February 2022

Historians writing in Latin show only intermittent interest in mystery cults; but when they do, their approach falls broadly into three different patterns. At times the cults are described in their local context, and treated as alien to a greater or lesser degree, though recognizable and sometimes acceptable to Roman participants. Secondly, they are sometimes treated as more or less indistinguishable from the rest of the religious landscape at Rome—but in those cases all sense of foreignness disappears, and there is no mention of initiation or anything distinctive about the experience of those cults. Thirdly, those more distinctive aspects may be emphasized, but only when the cults are treated as something dangerous and hostile to Rome, and are assimilated to ideas of secrecy and conspiracy.