bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of solitary cecum diverticulitis – Single-Center Experience
Authors: Gonullu Emre , Yigit Merve , Mantoglu Baris , Capoglu Recayi , Harmantepe Tarik , Gunduz Yasemin , Altintoprak Fatih , Bayhan Zulfu , Erkorkmaz Unal
Published: May 2021

Objective: Cecal diverticulitis may be encountered as a real etiological factor in 1/300 appendectomies. Differential diagnosis of acute appendicitis and cecal diverticulitis is crucial because of the different treatment methods. Our aim is to reveal the importance of distinguishing acute appendicitis from cecal diverticulitis.
Methods: The data of patients who were admitted to the hospital between 2015 and 2019 with the complaint of abdominal pain and then finally diagnosed with colon diverticular disease, colon diverticulitis, or acute appendicitis, analyzed retrospectively.
Results: A total of 19 cecum diverticulitis patients were detected during surgery for acute appendicitis or during clinical and radiological evaluation. 1247 appendectomies were evaluated; the final diagnosis was observed as cecal diverticulitis in 5 patients (0,4%). One hundred nineteen patients diagnosed with colonic diverticulitis at admission were evaluated, while 105 (88,2%) of them had left-sided diverticulitis, 14 (11,7%) of them had solitary cecal diverticulitis. All of the solitary cecal diverticulitis patients were treated conservatively, except one patient who has Hinchey 3 diverticulitis.
Conclusion: Differential diagnosis of cecum diverticulitis with acute appendicitis is important because cecum diverticulitis can be managed as conservatively in most cases. In order to prevent unnecessary surgical interventions, this importance has increased, especially during the COVID-19 pandemic period.
Hand injuries in polytrauma patients.
Authors: Żyluk Andrzej , Fliciński Filip , Pakulski Cezary
Published: May 2021

Hand and forearm injuries are relatively rare in polytrauma patients; their incidence is estimated on 2-5%. They are usually not life threatening, and, therefore are considered of secondary importance, replaced by serious injuries of other body parts. However, they should be treated immediately after stabilization of the general condition of the patients, as their delayed fitting may result in serious dysfunction of the hand. The aim of this study was determine the incidence, distribution and methods of treatment of hand and forearm injuries in the patients treated in Polytrauma Centre of the SPSK 1 in Szczecin, over the period of 4 years. Medical records of 16 patients, 11 men (65%) and 5 women (35%) at the mean age of 34 years (range 19-62) who were treated in Polytrauma Centre and sustained an additional injury to the hand and/or forearm were analysed.
Results. The most common component of polytrauma with associated hand injury was major bone fractures (spine, pelvis and extremities) - 12 cases (70%), followed by chest - 11 (65%), maxillofacial - 9 (53%), brain - 8 (47%) and abdominal injuries - 5 (29%). The most common injury of the distal upper limb was fracture of the distal radius - in 9 patients (53%). Two patients sustained excessive crush-degloving injuries which were primary cause of their admission into Polytrauma Centre. Nine patients required surgery, predominantly fixation of the distal radius with plate. All patients survived. The importance of the correct fitting of hand injuries, promptly after stabilization of the general condition of polytraumatized patients was emphasized.
Adulthood of patients after oesophageal atresia repair- General Surgeon's Guide
Authors: Tokarz Anna , Rogula Wojciech , Tokarska Karolina , Tarsa Maciej , Urban Witold , Zbroja Karolina , Górecki Wojciech
Published: May 2021

Introduction
Despite proper surgical management in neonatal period, congenital oesophageal atresia [OA] may present serious source of lifelong disorders. The objective of our study is to present the most important facts about oesophageal atresia, types of treatment and possible complications which might demand surgical management in adult life. We would like to familiarize general surgeons with this matter to provide OA patients with proper medical care.
Materials and Methods
We made a thorough literature review of Medline database and Cochrane Library with "(o)esophageal atresia", "long gap", "surgery" and “follow-up” used as keywords.
Results
Long-term observation reveals that patients with OA may need help from general surgeons, however do not often look for it. Even after surgical repair in neonatal period, OA indispose to multiple concomitant disorders including gastroesophageal reflux disease, oesophagitis, strictures, epithelial metaplastic changes in the oesophagus or hiatal hernia development. Endoscopic follow-up should be systematically performed in OA patients’ population in order to early detection of possible pathologies.
Discussion
Advancement in medicine allowed to improve survival rates and adulthood is reached more often in population of OA patients. In the face of variety of concomitant problems, systematic long-term follow-up seems to be crucial in proper medical care in these patients.
Polymeric locking clips [Hem-o-lok] versus Metallic clips in elective Laparoscopic Cholecystectomy: A Retrospective study of 1496 patients
Authors: Madhavan Shibumon , Pandey Anshuman , Masood Shakeel , Kumar Suneed , Chauhan Smita , Kumar Dinesh , Jha Sneha
Published: May 2021

Background
Laparoscopic cholecystectomy is one of the most commonly performed operation. Various methods for securing the cystic artery and cystic duct are described in literature. We aim to compare intra-operative and early post-operative outcomes of laparoscopic cholecystectomy using polymeric locking Hem-o-lok clips versus metallic ligaclips .
Patients and Methods
Retrospective study of prospectively maintained single institutional data including all consecutive patients who underwent elective laparoscopic cholecystectomy from 2013 to 2018. Patients in whom metallic ligaclips were used were grouped as Group I and those with Hem-o-Lok were grouped as Group II. The early post-operative outcomes of the two groups were compared.
Results
Total 1496 patients were included in the study; 836 patients in Group I and 660 in Group II. Study included 29.1% males and 70.9% females with mean age of 43.6 years. Hem-o-lok clip was better in securing wide cystic duct compared to metallic clips. Metallic clip failed to secure 8 out of 44 wide cystic duct compared to 0 out 70 with Hem-o-lok clips (p=0.002). The post-operative outcomes of both groups were comparable. There were no cystic duct leak, post- operative bleeding or major bile duct injuries in either group.
Conclusion
Use of Hem-o-lok clip is safe in laparoscopic cholecystectomy due to ease of application and security. Hem-o-lok is more useful in patients with thick and wide cystic duct which are difficult to secure with metallic clips with low risk of leak.
Key words: Laparoscopic Cholecystectomy, Hem-o-lok clip, Metallic clip, Wide cystic duct
Gastroesophageal reflux disease – from the point of view
of a gastroenterologist, otolaryngologist and surgeon
Authors: Jurkiewicz Dariusz , Waśko-Czopnik Dorota , Pietruszewska Wioletta , Tarnowski Wiesław , Barańska Magda , Kowalczyk Magdalena , Jaworski Paweł
Published: May 2021

Gastrooesophageal reflux disease is the regurgitation of stomach contents into the esophagus, which causes troublesome
symptoms or complications for the patient. Before starting the treatment, it is always necessary to objectively confirm
gastroesophageal reflux disease, especially in correlation with ENT symptoms, as extra esophageal complications.
In diagnostics, the "gold standard" is a 24-hour impedance-pH supplemented with endoscopy. Treatment without objective
confirmation of the disease is not recommended, the more so that non-acid gas proximal reflux, detectable only in the MIIpH
test, causes the greatest number of laryngological complications. It is important to confirm the coexistence of clinical
symptoms of GERD with ESS. Considering the time of treating the disease and its consequences, it is worthwhile to be
cautious and careful with the diagnosis of the disease, and the treatment should be carried out for a long time in relation
to the recommendation, preferably in cooperation with an ENT specialist and gastroenterologist. The greatest therapeutic
effectiveness is achieved by combining PPI with itopride while maintaining the appropriate doses of drugs and observing
a sufficiently long duration of treatment, while maintaining the correct dose reduction and drug discontinuation regimen.
In case of failure of pharmacological treatment, antireflux surgery should be take into consideration.
APPROPRIATENESS OF REFERRING FOR COLONOSCOPY: RESULTS FROM A CROSS–SECTIONAL STUDY IN PRIMARY CARE
Authors: Sánchez-Ruano Núria , Hervás Amparo , Vilaseca Josep
Published: May 2021

Background:
Colorectal cancer (CRC) is the third most commonly diagnosed malignant cancer and the fourth leading cause of cancer-related death in the world. The role of family doctors in the diagnosis and management of gastrointestinal disorders, including screening for CRC, is crucial.
Aim of the study:
To examine the appropriateness of colonoscopy referrals in a primary healthcare setting.
Material and methods:
The clinical reports of all colonoscopies ordered during 2017 at a primary care center (317 in total) were examined. The reasons for referral, the findings of the colonoscopies, and the pathology of identified polyps were extracted from the reports and summarized.
Results:
The patients included 161 males (50.8%) and 156 females (49.2%) with a mean age of 63.6 years. The most frequent reasons for ordering a colonoscopy were a personal history of polyposis/CRC (n = 94, 29.7%), rectal bleeding (n = 57, 18%) and anemia (n = 35, 11%). Only 67 (21%) of the colonoscopies performed showed a normal result, whereas 250 (79%) had abnormal findings. The main findings of the colonoscopies were polyps (n = 119, 37.5%), diverticulosis (n = 61, 19.2%) and hemorrhoids (n = 37, 11.7%). The main results for polyp pathology were tubular adenoma with low-grade dysplasia (n = 70, 58.8%), hyperplastic polyp (n = 27, 22.7%), adenocarcinoma (n = 9, 7.6%) and inflammatory polyp (n = 4, 3.4%). Colorectal cancer was found in a total of 14 (4.4%)
Conclusions:
patients.The referral for colonoscopy by family doctors is appropriate.
Physical Activity of the Elderly in Light of the 2020 WHO Guidelines
Authors: Husejko Jakub P. , Strugała Maciej , Modrzejewski Mateusz , Wąsicki Mariusz , Kędziora-Kornatowska Kornelia , Podhorecka Marta
Published: May 2021

Introduction: Demographic assessment in Poland allows to indicate progressive aging of society, associated with the growing number of people with cardiovascular diseases, cancer and disabilities of various origins. In November 2020, the World Health Organization (WHO) issued recommendations for physical activity which, for the first time, also applied to people suffering from chronic diseases and disabilities. Compliance with the guidelines is part of the prevention regarding both chronic diseases and disabilities with various etiology.

Study aim: The aim of the study is to present the latest guidelines of the World Health Organization and based on the cited literature, to answer the following question: How can changes in physical exercise have impact on the functional state of people above the age of 60?

Materials and methods: The study objective was carried out based on analysing the quoted WHO guidelines and the cited literature related to the recommended physical activity of people above the age of 60 in overcoming various origins of their disabilities and lesions. Within this context, the following provisions were analysed: WHO guidelines from 2020 and quoted literature in the number of 32 items.

Results: Physical activity may delay human aging by as many as 2 decades, improving the systemic condition, positively affecting the symptoms of a depressive disease, inhibiting neurodegenerative diseases and has a beneficial effect on the health of patients suffering from metabolic diseases.

Conclusions: Regular physical activity of people above the age of 60 definitely has a positive effect on their functioning, both in terms of disabilities and diseases of various origins.
La dynamique hydro-sédimentaire du bassin de la rivière Jiu : approche systémique et multi-échelle
Authors: Morosanu Gabriela Adina
Published: May 2021

The present book, titled “The Hydro-sedimentary dynamics of the Jiu River Watershed. A systemic and multi-scale approach” sets about to investigate the dynamics of liquid and solid flows in a challenging watershed represented by the Jiu River Basin. The Jiu River (with a length of 339 km) is one of the main tributaries of the Danube in its Romanian sector, and its watershed stretches over an area of 10,080 km2, in SW Romania. Jiu River Basin is defined by complex geographical features, determined by a variety of natural and socio-economic factors. From an economic standpoint, the element that makes Jiu’s watershed stand out among other comparable rivers is the presence and exploitation of coal in its upper sector (bituminous coal) and middle sector (lignite), as these activities have left their mark on the quality of the water and the quantity and origins of fine sediments. In this study, we relied upon the existence of coal resources in order to investigate the hydro-sedimentary dynamics in the Jiu River Basin and identify the fine sediment sources, by performing an analysis of coal particles found in the fine sediments, which was carried out through different laboratory methods.
Competentele sociale si emotionale. Exemple de bune practici pentru profesori si consilieri scolari
Authors: Andrei Angela
Published: May 2021

Lucrarea de fata contine 38 de exemple de buna practica, colectate ca urmare a apelului catre Centrele Judetene de Resurse si Asistenta Educationala (CJRAE)/Centrul Municipiului Bucuresti de Resurse si Asistenta Educationala (CMBRAE), lansat de Institutul de Știinte ale Educatiei din Bucuresti, in septembrie 2019 pentru realizarea conferintei nationale Euroguidance Romania 2019 si ca urmare a apelului catre CJRAE/CMBRAE, lansat de Centrul National de Politici si Evaluare in Educatie, Unitatea de Cercetare in Educatie (CNPEE-UCE) din Bucuresti, in mai 2020 pentru contributii pe tema dezvoltarii competentelor sociale si emotionale. Lucrarea contine 26 jurnale de reflectie, 6 programe si 6 activitati de dezvoltare a competentelor sociale si emotionale ale elevilor din invatamantul primar, gimnazial, liceal si profesional. Jurnalele de reflectie includ prezentari ale unor programe si activitati de dezvoltare a competentelor sociale si emotionale ale elevilor, dar si cursuri de formare adresate profesorilor si consilierilor scolari
PArticole de suflet, vol. II
Authors: Gojgar Pr. Mihai
Published: May 2021

Aculturarea stilistica prin care parintele Mihai Gojgar castiga in scris este entuziasmanta. Nu sunt talcuiri ale Evangheliei, ci redescoperiri ale temeiurilor sale. Credinta nu are nevoie de argumente, ci de fundamente. De fundamente luminoase. Unele dintre texte poarta titluri si post-titluri asezate in paranteze. Semnul adaptarii din... scris pe care autorul o face continutului sau. O nevoie fireasca in lucru ca jurnalist. Editorialistul se stinge luminand in duh omiletic. Aici e cheia frumusetii textelor acestora. Departe de a fi moraliste ori ”lectionarde”, randurile ce le veti parcurge pot produce o serie de adaptari cuminti in tahicardia ce ne incearca la vreme de zgomotoasa pandemie. Cum intelege parintele inimile ascultatorilor? Desigur, ascultandu-le. Se simte in texte grija pastorala. Ce care mustra cu drag si da masura asteptarilor duhivnicesti. Titlul ne arata aceasta. PArticole de suflet se dovedesc a fi miride din marea prescura a vietii duhovnicesti a unei parohii cu un profil misionarspecial, dinamic si viu. Pr. Conf. Dr. Constantin Necula
Psychosocial Characteristics of Images of Power in Mass Communication
Authors: Busu Oprea-Valentin
Published: May 2021

Different categories of specialists in social sciences as well as different categories of proffesional communicators will find here a synthetic picture of the more significant classical and modern theories regarding the role of power as a ”Fundamental phenomenon that regulates and organizes social life”, and as it appears to us: a brute force, an alluring mermaid, a possessor of saving solutions and skills etc. Also, because we live in a time when direct communication is outdated, the author analyzes the media system mainly under the aspect of image construction or personalized representation of power. A special mention also deserves the fact that the author achieves his goals by using a multiple perspective - social, psychosociological, anthropological. This approach is not a final decryption of the contents of the concepts of power and communication - image, but is part of a continuum of efforts to reveal the rich, challenging social reality, thus bringing his own contribution both to finding answers and to the birth of new questions.
Aceitação do uso de Slides como Recurso Didático por Alunos do Ensino Superior
Authors: Bonilla Rosineide Da Silva , Santos Jonas Martins , Vilela Tânia Jucilene Vieira
Published: May 2021

O trabalho traz discussões sobre a aceitação dos alunos (as) no uso dos slides como recurso didático. Abordaremos discussões acerca do âmbito educacional e as tecnologias digitais, com vistas a contribuir com a relação entre professor, aluno no ensino superior nos cursos de tecnologia das universidades UNEB e UFGD presenciais e a distância. Dessa forma, a pesquisa bibliográfica inicia-se por meio dos conceitos sobre a importância das tecnologias da informação e comunicação no meio educacional. A metodologia utilizada será de cunho bibliográfico e pesquisa quantitativa-qualitativa aos discentes, visando a possibilidade de chegar há discussões que possam responder nossos questionamentos sobre a problemática levantada em nossa pesquisa, de como está sendo a aceitação do uso das ferramentas tecnológicas como mediação pedagógica no ensino superior. Para o embasamento teórico utilizamos KENSKI (2012), SOUZA; LINHARES (2012) e MENEGAZ (2016) que destacam sobre o tema abordado, enfocando questões significativas para nossas reflexões na área educacional pedagógica por meio da tecnologia no que compete o ensino-aprendizagem e seus recursos. Os resultados serão de grande valia para que possamos praticar essas questões sobre a era digital e suas ferramentas que poderão ser usadas com mais propriedade nas aulas dos futuros profissionais da educação.
O uso do Whatsapp, Google Drive, E-Mail e Moodle na Coordenação de uma Escola Pública
Authors: Abreu Maria Aparecida Rondis Nunes de , Batista Erlinda Martins , Loiola Luziety Adalgisa Gimenez
Published: May 2021

Este artigo relata o uso do WhatsApp, e-mail, Google Drive e Moodle como ferramentas de comunicação entre coordenação pedagógica e docentes na Escola Municipal Professor Licurgo de Oliveira Bastos em Campo Grande, MS. O diálogo virtual amplia a gestão. Semanalmente, um docente encarrega-se de compartilhar o planejamento para análise do coordenador e docentes adaptando-o às turmas. Vislumbra-se a reflexão dos professores no contexto educacional para que surjam novas pesquisas aprofundando o uso das TICs e que órgãos governamentais invistam significativamente em prol da melhoria da infraestrutura fundamental ao uso destas ferramentas virtuais e na formação continuada dos professores e coordenadores.
Bullying e Cyberbullying: como os professores estão sendo preparados para lidarem com esse problema?
Authors: Nascimento Sulamita Barreto , Eleotério Valdênia Rodrigues Fernandes
Published: May 2021

O presente artigo é resultado de um Trabalho de Conclusão de Curso do Curso de Pedagogia da Universidade Federal de Mato Grosso do Sul, Campus de Aquidauana. Tem como tema o Bullying e cyberbullyin. O objetivo geral é: identificar como os professores do município de Aquidauana, das redes estadual e municipal estão sendo capacitados para combater os problemas. Tivemos como metodologia a pesquisa bibliográfica e de campo. A técnica escolhida para coleta de dados foi o questionário. Os resultados mostram que o combate de alguma forma é feito nas escolas participantes da pesquisa. Concluímos que para minimizar/combater essas atitudes é necessária mais capacitação e diálogo permanente na comunidade escolar.
Safety of Healthcare Workers During the Airway Management in Adult and Pediatric Patients with COVID-19
Authors: Rahmani Farzad , Mahmoodpoor Ata , Salmasi Shiva , Ebrahimi Bakhtavar Haniyeh
Published: May 2021

: Since December 2019, the outbreak of coronavirus disease 2019 (COVID-19) has spread worldwide. Although the majority of patients show mild symptoms, the disease can rapidly progress in severe cases and develop acute respiratory distress syndrome (ARDS) that may lead to therapeutic interventions, including oxygenation, tracheal intubation, and mechanical ventilation. It is suggested that the new coronavirus spreads mostly via droplets, surface contact, and natural aerosols. Hence, high-risk aerosol-producing procedures, such as endotracheal intubation, may put the healthcare workers at a high risk of infection. In the course of managing patients with COVID-19, it is essential to prioritize the safety of healthcare workers. Hence, this review study aimed to summarize new guidelines and proper airway management in adult and pediatric COVID-19 patients.
Efficacy of an Early Self-care-Based Education Program on the Self-evaluation of Primiparous Postpartum Mothers: A Randomized Controlled Clinical Trial
Authors: Chamangasht Maryam , Akbari Kamrani Mahnaz , Farid Malihe
Published: May 2021

Background: During the postpartum period, due to the lack of knowledge about postpartum complications and care, women, especially primiparous women, lack the adequate skills to adapt to new conditions and have no confidence to care for themselves and their infants. The early mothers' assessment, education, counseling, and nursing interventions can increase their adaptation and reduce their incompatible responses to their infant and partner. Objectives: This study aimed to examine the effect of early self-care based education program on primiparous women’s self-evaluation. Methods: A randomized controlled clinical trial was conducted from May to October 2018 on 58 primiparous women referred to the Neonatal Screening Center in Karaj (IRAN). A random allocation method was applied to select intervention and control groups. The data were collected using a three-part questionnaire consisting of general, developmental, and health deviation postpartum evaluation made by researchers. The intervention group received three education sessions throughout the 3 - 5, 10 - 15, and 17 - 22 days after childbirth. The control group received routine postpartum care. Data were analyzed by descriptive statistics (such as mean, standard deviation, and absolute frequency) and statistical tests (including t-test, paired t-test, and chi-square) or non-parametric statistical tests (e.g., the Wilcoxon and Mann-Whitney test) using SPSS version 19. Results: Before the intervention, there was no statistically significant difference in the mean total self-evaluation scores between the intervention (131.269 ± 12.742) and control (137 ± 9.600) groups (P-value = 0.073), but six weeks after delivery, a significant difference was observed in the mean self-evaluation scores between the intervention (149.692 ± 7.625) and control (122.923 ± 11.495) groups (P-value < 0.001). Conclusions: The results of this study showed that early self-care education program was effective for primiparous women's self-evaluation and increased the postpartum adaptation of the women.
Introduction to the Study of Mechanical Properties of Terpolymer PP/EPDM Mixtures
Authors: Scagliusi Sandra R. , Carvalho Elizabeth C.L. , Lugão Ademar B.
Published: May 2021

Thermoplastic elastomers (TPEs), based in PP (Polypropylene) / EPDM (Ethylene Propylene Diene Monomer) have as purpose improving PP resistance and impact, aiming to a more comprehensive use in automotive market, among edifications, construction and packaging sectors, due to their recyclability properties. PP is a commodity, with a high melting point, high mechanical resistance and low density, posing a balance between physical and mechanical properties; in addition, it shows an easy processing, at low cost. In order to minimize this deficiency, EPDM, an impact modifier, can be used. Nevertheless, most of polymeric blends are incompatible and immiscible, i.e., show a mutual and limited solubility and in most of cases, a high interfacial tension. However, there is a relatively low interfacial tension (force which acts on transformation of a continuous structure in a dispersion) between PP and EPDM (approximately 0.3 mN.m-1), reducing the rate of breakup and facilitating the build-up of a continuous structure. This work aims to the study of compatibility of PP and EPDM blends and variation of mechanical properties, emphasizing that many properties of thermoplastic elastomers can be processed according with conventional thermoplastics methods: herein, PP/EPDM blends, 90/10, 80/20, 70/30 and 50/50 were characterized according to: Mechanical essays, Differential Scanning Calorimetry, Thermogravimetric Analyses, Melt Flow Index, Izod Impact Strength and Dynamic mechanical Analyses.
The Effect of Aluminium Surface Treatments on the Bonding Properties of Silica-Modified Epoxy Adhesive Joints: A Statistical Approach
Authors: Santos Francisco M. Dos , Oliveira Lívia A. de , Bueno Alysson H. S. , Freire Rodrigo T. S. , Silva Leandro José da , Pino Gilberto García del , Panzera Tulio H.
Published: May 2021

A full factorial design is carried out to investigate the effects of different surface treatments, the inclusion of silica microparticles and the use of wash primer on the apparent shear strength and adherent strength of single-lap aluminium joints. Scanning electron microscopy, surface energy and roughness measurements are performed to characterise the aluminium surface. The results show that the use of wash primer decreases the apparent shear strength of the joints significantly. The cohesive failure of the primer is the main cause of the reduction in strength. On the other hand, the inclusion of 10 wt.% of silica microparticles in the adhesive layers increases the shear strength by 26%. Surfaces treated with NaOH for one minute, without using a wash primer, result in the most resistant joint. In contrast to the apparent shear strength, adherent strength is most effective when only degreasing is considered.
Agenda 2030. How to reach the goals and measure success at the local level
Authors:   Nordregio, Sánchez Gassen Nora , Huynh Diana , Penje Oskar , Ström Hildestrand Åsa , Salolammi Pipsa
Published: May 2021

The report summarises the main insights and lessons learned from the webinar series. The report is structured as follows: the first section provides background information on the webinar series, the topics that were addressed, as well as the participants that registered for the series. A map then shows the municipalities and regions that were in the focus of the webinar series. The main part of the report consists of six sections, one for each webinar. In each of the six sections, we highlight the main lessons and good practices that our keynote speakers shared with us. The texts also highlight challenges in the work with the SDGs and describe how they were addressed by the municipalities and regions.
Do Third Molars Play a Role in Second Molars Undergoing Endodontic Treatment?
Authors: UYSAL Betül Aycan , KAYA Bilal , GUNESER Mehmet Burak
Published: May 2021

Background and aim: This study evaluated the rates of second molars undergoing endodontic treatment due to partially or fully erupted lower and upper third molars. Materials and Methods: Radiographic data from 579 patients were analyzed to calculate the rates of second molars undergoing endodontic treatment due to third molars and other reasons. Descriptive statistics were expressed as numbers and percentages for categorical variables. The chi-square test was used to determine the relationships between categorical variables. Results: The rate of second molars undergoing root canal treatment for reasons unrelated to third molars was statistically higher than that of second molars undergoing treatment because of third molars (p < 0.001). The rate of lower second molars with endodontic treatment was significantly higher than that of upper second molars (p < 0.001). There was no statistically significant difference between partially and fully erupted third molars causing root canal treatment of second molars (p = 0.344). Conclusion: Root canal treatment of second molars can be related to fully or partially erupted third molars. All preventive measures should be taken to avoid the need for root canal treatment.
Combinatorial deployment of F-actin regulators to build complex 3D actin structures in vivo
Authors: Xie Yi , Budhathoki Rashmi , Blankenship J Todd
Published: May 2021

Despite extensive studies on the actin regulators that direct microfilament dynamics, how these regulators are combinatorially utilized in organismal tissues to generate 3D structures is an unresolved question. Here, we present an in-depth characterization of cortical actin cap dynamics and their regulation in vivo. We identify rapid phases of initiation, expansion, duplication, and disassembly and examine the functions of seven different actin and/or nucleator regulators (ANRPs) in guiding these behaviors. We find ANRPs provide distinct activities in building actin cap morphologies – specifically, while DPod1 is a major regulator of actin intensities, Cortactin is required for continued cortical growth, while Coronin functions in both growth and intensity and is required for Cortactin localization to the cap periphery. Unexpectedly, cortical actin populations recover more rapidly after regulator disruption, suggestive of a deep competition for limited G-actin pools, and we measure in vivo Arp2/3 recruitment efficiencies through an ectopic relocalization strategy. Our results illustrate how the coordination of multiple actin regulators can orchestrate organized and dynamic actin structures in a developmental system.
DE-CRYSTALLIZATION OF CALCIUM OXALATE AND URIC ACID CRYSTALS BY USING MUSA PARADISIACA STEM EXTRACT
Authors: M H Aishwarya , A P Anusha , Bhat Pritam , Nandi Sahana , K Geetanjali , S V Hiremath , K J Pavan
Published: May 2021

Concentrated urine, the minerals and acid salts adhere together to form hard deposits known as kidney stone. The most common minerals found in crystals are calcium oxalate, calcium phosphate, uric acid and struvite. In majority cases renal stones were removed by surgical treatment like ESWL, ureteroscopy and percutaneous nephrolithotomy but unfortunately recurrence of stone was observed in about 50% cases. Medicinal plants have been known for long period of time as an excellent source of therapeutic agents for various diseases including urological disorders and Banana stem extract is said to be useful in de-crystallization of Kidney stones. The present study reveals the effectiveness of Banana stem extract when treated on these crystals showed decrease in the size and weight which was measured by weighing balance at different intervals. The study revels considerable decrease in the weight of stone from 0.4440 gram to 0.3704 gram. The result shows that effective use of banana stem extract can be effectively used to degrade the kidney stones.
ALEPA CHIKITSA IN KUSHTA: A CRITICAL REVIEW
Authors: Bharadwaj Muktha K A , Kumar Vinay K N
Published: May 2021

Skin is the largest organ of the body which is in direct contact with the environment, the status of which reflects the status of healthy body. When skin gets affected, it not only has its impact on Somatic system but also on Psychological and Social aspects. In Ayurveda, skin diseases are broadly classified into Kushta which is a Bahya rogamarga janya vyadhi and gets vyakta in Twak and the treatment of which consists of both external and internal treatments which are considered as bahirparimarjana and antarparimarjana chikitsa. Bahirparimarjana chikitsa like Udvartana, Takradhara, Parisheka and Lepa all have very beneficial effects in treating this disease called Kushta in the same way as that of Shodhana. Alepa chikitsa has been given prime importance among these Bahir – Parimarjana chikitsa as it does Twak prasadana, rakta prasadana, kandu vinashana and daha prashamana. Hence, an attempt has been made to compile and critically analyse the use of different lepas helpful in Kushta roga.
AN INQUISITIVE INSIGHT INTO THE PATHOPHYSIOLOGY AND MANAGEMENT OF GRAHANI ROGA
Authors: Yadav Sunitha Dhirendra , Sudhakar Padamata Sai , Bulliah Talakayala , Srinivas Kurlapati , Yeragorla Ratna Priya Darsini
Published: May 2021

Grahani roga has been a challenge owing to its preponderance in the present lifestyle conditions where the dietary practice has gone completely out of sync. Grahani roga simulates Irritable Bowel Syndrome considering its cardinal features. It is prevalent among 10-20% of adults and adolescents, predominantly in females. Despite extensive research, an effective treatment and prevention strategy has not been developed due to its heterogenous etiopathogenesis. In this paper, neurological etiopathogenesis and pathophysiology of grahani roga is elaborated. Pathophysiology of Samana vata with respect to the Auerbach’s plexus and Vyana vata with respect to Meissner’s plexus of the enteric nervous system, in etiopathogenesis of grahani roga has been elucidated. Ghrita is considered as the probable mode of treatment due to its Vatahara and Agnideepaka properties.
A REVIEW ON HEALTH ISSUES AMONG ADOLESCENT GIRLS: AN AYURVEDIC PERSPECTIVE
Authors: AK Nithya , MK Sharada , AK Anoop
Published: May 2021

Adolescence is a vital stage for both boys and girls, but it is more important for girls due to menstrual complications. So, they need special care and considerations. Adolescence is a time for growth spurts and puberty changes. Therefore, adolescence is a stage which will breed great stress and strain among parents. According to Ayurveda these changes develop during this period is known as rajo darshana or menarche, which is the product of Rasa, flows out of the body in every month, after the age of twelve years and slowly reduces by the age of fifty years. Sexual and other physical maturation that happens during puberty occurs mainly due to hormonal changes. So, this article is an effort to throw light on the role of health issues and their Ayurvedic management among adolescent girls.
A REVIEW ON PHYTOCHEMICAL, ANALYTICAL, PHARMACOLOGICAL AND NUTRITIONAL SIGNIFICANCE OF SOLANUM TUBEROSUM
Authors: Ramakrishna K , Swathi K , Sunitha N , Sree P Spoorthi , Naveen R
Published: May 2021

Potato known as Solanum tuberosum belongs to Solanaceae family. The whole parts of the plant are meant for their medicinal use. The chemical constituents present in potato are having numerous pharmacological activities. The main chemical constituents of potato are phenolic compounds, flavonoids, anthocyanins, alkaloids. The reported pharmacological activities of potato are antibacterial, anti-obesity, anti-allergy, anti-inflammatory, anti-ulcer. Potato also contains vitamins such as vitamin-B6, vitamin-B3, pantothenic acid and minerals like potassium, manganese, phosphorous, copper, it also contains some amount of fiber. The geographical origin and distribution, nutritional value, phytochemical constituents have been mentioned in this present review article.
Engklek Game and Its Benefits for Early Children’s Development
Authors: Sukoyo Joko , Kurniati Endang , Utami Esti Sudi
Published: May 2021

This research aims to describe the engklek game and its benefits for early children's development. The applied research method is a qualitative methodology with human data and non-human data sources. The data was collected by the interview, observation, and document analysis. Meanwhile, the data analysis was done by using Mile and Huberman interactive analysis model through data reduction, display, and conclusion. The findings showed that the engklek game developed in Boyolali municipality had two types of the engklek game. They are an airplane engklek and a mountain engklek. The game could be played by both males and females with 2-5 persons. It is usually played in the morning or the afternoon in the yard. Engklek games could be used to stimulate the physical, cognitive, social, emotional, and linguistic development of children. The physical skill consists of rough and fine motoric development, obesity reduction and leg muscle strengthening. The cognitive skill consists of geometry concept, calculation, estimation, problem-solving learning, and interpersonal quotient improvement. Social skill consists of socializing and honesty. The emotional skill consists of children's training to not be sloppy and stress reduction. Meanwhile, the linguistics skill consists of the word - sentence management skill and contextual language usage.
Effects of Family Education on Children's Personal Development
Authors: Ngoc Nguyen Thi
Published: May 2021

Today, it is not difficult for parents to find information, knowledge about how to raise children on the Internet or book stores. However, the knowledge and methods that we apply to children in order to promote their efficiency is a matter that make us take it into consideration. And if we choose the wrong method, or apply the wrong teaching method, it might have not-good influence on the process of formation and development. This paper is based on personal opinion, and is completed by the method of searching for information, documents and previous studies. In the article, there are several parenting methods used by Vietnamese parents and the impact of those methods on the formation of children 's personality. Hopefully, parents can adjust their ways of teaching, choose the best and most appropriate methods to teach their children. The paper is also completed by the support of some respondents who are living in Vietnam with the hope that we can find out some effective solutions when teaching children at home The results of the paper shows that the role of famlily plays a rather important, that is, parents needs more attention in order to protect and develop their children’s skills and necessary knowledge.
An Assessment of Cultural and Heritage Tourism Products in Kampung Hujong Permatang and Kampung Permatang in Kuala Selangor
Authors: Saaidin Munira Binti , Ahmad Amri Bin
Published: May 2021

The purposes of this study were to explore the availability and conditions of the cultural and heritage products in Kampung Hujong Permatang and Kampung Permatang in the Hujong Permatang sub-district of Kuala Selangor. The data and information were collected via observations and unstructured interviews, guided by using checklists on resources such as community, site, physical and natural, environmental, and the tourism facilities and services, that were to be examined. The findings indicated some very interesting and unique cultural and heritage products that were available and could be promoted as tourism products such as the historical sites which had the graves of famous warriors at Bukit Raja, the old mosque of Kampung Permatang, the traditional Bugis and unique Malay houses, the Malay art of self-defence called Silat Lincah, the almost extinct traditional dance called Dabus with the accompanying musical instruments, and the handicrafts made of jute fibres. Proper planning for tourism development which should include all the stakeholders, especially the community members, had be carried out at the onset of ideas for improvement of the villages.
The Importance of Governance in Digital Transformation: A Case Study of e-CRM Implementation in a Malaysian Petrochemicals Company
Authors: Radzi Mohd Shaiful Ridwan , Tajudin Misyer Mohamed , Musa Normaziah Che , Rose Roslan Mohd
Published: May 2021

Many organizations embrace digital technologies to drive changes in enterprise business models and ecosystems that will not only enable them to weather the increasing environmental dynamics but also thrive on it. However, numerous internal and external factors have caused very few of them to continue their digital transformations in the right direction. For the rest, the journey to digital transformation have not resulted with businesses achieving complete value of a digitally-enabled change. Likewise, most Malaysian companies who have invested significantly in their digital endeavor have obtained very basic levels of return on their investments. This research examines the effects of governance on digital transformation by scrutinizing the implementation of e-CRM system at a Malaysian petrochemicals company. An exploratory study was initiated by interviewing key people at the company, leading to the adaptation of a survey questionnaire. Data was collected from 295 employees at various levels of management. Correlation analyses were carried out based on the parametric data. Governance was found to be significantly affecting digital transformation awareness, implementation and quality. Such findings demonstrate the importance of governance for supporting strategic decision making to deploy digital transformation in the manufacturing sector of an emerging economy.
Image quality assessments according to the angle of tilt of a flex tilt coil supporting device: An ACR phantom study
Authors: Lee Ho Beom , Jang Ji Sung , Lee Ki Baek , Kim Sung Min
Published: May 2021

In this study, we assessed how image quality depends on the angle of tilt of a flex tilt coil supporting device during an MRI examination. All measurements were performed with an American College of Radiology (ACR) MRI phantom using a flex tilt coil supporting device. All images were analyzed using an automatic assessment method following the ACR MRI accreditation guidance. Image quality was compared between acquisitions grouped according to the angle of tilt of the coil supporting device: group A (Flat mode), group B (10˚), and group C (18˚). All measured image qualities were within the ACR recommended criteria, regardless of the angle of tilt of the flex tilt coil supporting device. However, statistically significant differences between the three groups were found for slice thickness, position accuracy, image intensity uniformity, and SNR (P < 0.05, ANOVA). The flex tilt coil supporting device can provide sufficient image quality, passing the criteria of the ACR MRI guideline, despite differences in slice thickness, slice position accuracy, image intensity uniformity, and SNR according to the angle of tilt.
Intrinsic detector sensitivity analysis as a tool to characterize ArcCHECK and EPID sensitivity to variations in delivery for lung SBRT VMAT plans
Authors: Alharthi Thahabah , Vial Phil , Holloway Lois , Thwaites David
Published: May 2021

Purpose

To investigate intrinsic sensitivity of an electronic portal imaging device (EPID) and the ArcCHECK detector and to use this in assessing their performance in detecting delivery variations for lung SBRT VMAT. The effect of detector spatial resolution and dose matrix interpolation on the gamma pass rate was also considered.

Materials and methods

Fifteen patients’ lung SBRT VMAT plans were used. Delivery variations (errors) were introduced by modifying collimator angles, multi‐leaf collimator (MLC) field sizes and MLC field shifts by ±5, ±2, and ±1 degrees or mm (investigating 103 plans in total). EPID and ArcCHECK measured signals with introduced variations were compared to measured signals without variations (baseline), using OmniPro‐I'mRT software and gamma criteria of 3%/3 mm, 2%/2 mm, 2%/1 mm, and 1%/1 mm, to test each system's basic performance. The measurement sampling resolution for each was also changed to 1 mm and results compared to those with the default detector system resolution.

Results

Intrinsic detector sensitivity analysis, that is, comparing measurement to baseline measurement, rather than measurement to plan, demonstrated the intrinsic constraints of each detector and indicated the limiting performance that users might expect. Changes in the gamma pass rates for ArcCHECK, for a given introduced error, were affected only by dose difference (DD %) criteria. However, the EPID showed only slight changes when changing DD%, but greater effects when changing distance‐to‐agreement criteria. This is pertinent for lung SBRT where the minimum dose to the target will drop dramatically with geometric errors. Detector resolution and dose matrix interpolation have an impact on the gamma results for these SBRT plans and can lead to false positives or negatives in error detection if not understood.

Conclusion

The intrinsic sensitivity approach may help in the selection of more meaningful gamma criteria and the choice of optimal QA device for site‐specific dose verification.
Selective vulnerability to atrophy in sporadic Creutzfeldt‐Jakob disease
Authors: Younes Kyan , Rojas Julio C. , Wolf Amy , Sheng‐Yang Goh M. , Paoletti Matteo , Toller Gianina , Caverzasi Eduardo , Luisa Mandelli Maria , Illán‐Gala Ignacio , Kramer Joel H. , Cobigo Yann , Miller Bruce L. , Rosen Howard J. , Geschwind Michael D.
Published: May 2021

Objective

Identification of brain regions susceptible to quantifiable atrophy in sporadic Creutzfeldt‐Jakob disease (sCJD) should allow for improved understanding of disease pathophysiology and development of structural biomarkers that might be useful in future treatment trials. Although brain atrophy is not usually present by visual assessment of MRIs in sCJD, we assessed whether using voxel‐based morphometry (VBM) can detect group‐wise brain atrophy in sCJD.

Methods

3T brain MRI data were analyzed with VBM in 22 sCJD participants and 26 age‐matched controls. Analyses included relationships of regional brain volumes with major clinical variables and dichotomization of the cohort according to expected disease duration based on prion molecular classification (i.e., short‐duration/Fast‐progressors (MM1, MV1, and VV2) vs. long‐duration/Slow‐progressors (MV2, VV1, and MM2)). Structural equation modeling (SEM) was used to assess network‐level interactions of atrophy between specific brain regions.

Results

sCJD showed selective atrophy in cortical and subcortical regions overlapping with all but one region of the default mode network (DMN) and the insulae, thalami, and right occipital lobe. SEM showed that the effective connectivity model fit in sCJD but not controls. The presence of visual hallucinations correlated with right fusiform, bilateral thalami, and medial orbitofrontal atrophy. Interestingly, brain atrophy was present in both Fast‐ and Slow‐progressors. Worse cognition was associated with bilateral mesial frontal, insular, temporal pole, thalamus, and cerebellum atrophy.

Interpretation

Brain atrophy in sCJD preferentially affects specific cortical and subcortical regions, with an effective connectivity model showing strength and directionality between regions. Brain atrophy is present in Fast‐ and Slow‐progressors, correlates with clinical findings, and is a potential biomarker in sCJD.