bluuebunny/crossref_metadata_2025 huggingface dataset:
NUMERICAL SIMULATION OF THE REFLECTANCE SIGNAL FROM A SHORT-PULSE GAUSSIAN LASER BEAM INCIDENT ON HEALTHY AND MALIGNANT SKIN TISSUE
Authors: Coelho Pedro Jorge Martins
Published: August 2024

The application of short-pulse lasers in biomedical diagnosis and therapies has garnered significant attention in recent
years. Specifically, for human skin, the reflected laser signal can provide valuable information about tissue health,
as the optical properties of healthy and malignant tissues differ, leading to distinguishable signals. In this study,
a short-pulse Gaussian laser beam is applied to diagnose cutaneous tumors using two-dimensional axisymmetric
coordinates. This method extends previous studies that utilized one-dimensional approximations or top-flat laser
beams. The transient radiative transfer equation is solved using the discrete ordinates method. Scattering is described
by the Henyey-Greenstein phase function. A second-order Runge-Kutta method is used for time discretization, while
spatial discretization is handled using the finite volume method and the CLAM scheme. The skin is modelled as a
multi-layered medium with distinct optical properties for each layer. The temporal variation of the reflected signal from healthy skin tissue is compared to those from tissues with non-melanoma and melanoma carcinomas. Additionally,
the variation of the signal with the size of the tumor is investigated. The results show that different skin carcinomas of the same size produce reflected signals of different magnitudes, allowing for their identification, although this becomes more challenging at early growth stages. The reflectance varies with tumor size and growth stage.
Vascular Endothelial Growth Factor–B Blockade with CSL346 in Diabetic Kidney Disease
Authors: Cooper Melisa , Cherney David Z.I. , Greene Tom H. , Heerspink Hiddo J.L. , Jardine Meg , Lewis Julia B. , Wong Muh Geot , Baquero Elbalejandra , Heise Mark , Jochems Jeanine , Lanchoney Diana , Liss Charles , Reiser David , Scotney Pierre , Velkoska Elena , Dwyer Jamie P.
Published: August 2024

Key Points

The vascular endothelial growth factor B inhibitor CSL346 (8 or 16 mg/kg q4w) did not reduce urinary albumin-creatinine ratio at week 16 versus placebo in patients with type 2 diabetes mellitus and diabetic kidney disease.

CSL346 was generally well tolerated at both doses; however, CSL346 (16 mg/kg) significantly increased diastolic BP versus placebo.

Background

Increased vascular endothelial growth factor B (VEGF-B) expression in patients with diabetic kidney disease (DKD) is associated with increased lipid deposition in glomerular podocytes. Reducing VEGF-B activity in animal models of DKD using an anti–VEGF-B antibody improved histological evidence of glomerular injury and reduced albuminuria, effects attributed to prevention of ectopic lipid deposition in the kidney. CSL346 is a novel humanized monoclonal antibody that binds VEGF-B with high affinity. Targeting VEGF-B in patients with type 2 diabetes mellitus may improve DKD progression markers.

Methods

An international, randomized, double-blind, placebo-controlled, phase 2a study (NCT04419467) assessed CSL346 (8 or 16 mg/kg subcutaneously every 4 weeks for 12 weeks) in participants with type 2 diabetes mellitus and a urinary albumin-creatinine ratio (UACR) ≥150 mg/g (17.0 mg/mmol), and eGFR >20 ml/min per 1.73 m2. Efficacy, safety/tolerability, pharmacokinetics, and pharmacodynamics of CSL346 were evaluated. The primary analysis compared the change from baseline in log-transformed UACR between the two CSL346 dose groups combined versus placebo at week 16.

Results

In total, 114 participants were randomized. CSL346 did not significantly reduce UACR compared with placebo at week 16 (combined CSL346 group difference from placebo [95% confidence interval], 4.0% [−14.7 to 26.8]). Furthermore, no effect was seen in participant subgroups (degree of kidney impairment or sodium-glucose cotransporter 2 inhibitor use) or on urinary biomarkers reflecting proximal tubular injury. CSL346 was generally well tolerated; however, diastolic BP was significantly higher with CSL346 16 mg/kg versus placebo from week 2 onward, with differences ranging from +3.8 to +5.3 mm Hg (P = 0.002 at week 16).

Conclusions

CSL346 did not reduce UACR compared with placebo at 16 weeks in participants with type 2 diabetes mellitus and DKD and was associated with an increase in diastolic BP.

Clinical Trial registry name and registration number:

VEGF-B Blockade with the Monoclonal Antibody CSL346 in Subjects with DKD, NCT04419467.
Detecting cell types and densities in the tumor microenvironment improves prognostic risk assessment for breast cancer
Authors: Liu Pu , Zhang Xueli , Wang Wenwen , Zhu Yunping , Xie Yongfang , Tai Yanhong , Ma Jie
Published: August 2024

A comprehensive evaluation of the relationship between the densities of various cell types in the breast cancer tumor microenvironment and patient prognosis is currently lacking. Additionally, the absence of a large patch-level whole slide imaging (WSI) dataset of breast cancer with annotated cell types hinders the ability of artificial intelligence to evaluate cell density in breast cancer WSI. We first employed Lasso-Cox regression to build a breast cancer prognosis assessment model based on cell density in a population study. Pathology experts manually annotated a dataset containing over 70,000 patches and used transfer learning based on ResNet152 to develop an artificial intelligence model for identifying different cell types in these patches. The results showed that significant prognostic differences were observed among breast cancer patients stratified by cell density score (P = 0.0018), with the cell density score identified as an independent prognostic factor for breast cancer patients (P < 0.05). In the validation cohort, the predictive performance for overall survival (OS) was satisfactory, with area under the curve (AUC) values of 0.893 (OS) at 1-year, 0.823 (OS) at 3-year, and 0.861 (OS) at 5-year intervals. We trained a robust model based on ResNet152, achieving over 99% classification accuracy for different cell types in patches. These achievements offer new public resources and tools for personalized treatment and prognosis assessment.
Titration of Lentivirus v1
Authors: Adami Anita
Published: August 2024

This protocol is about titrating lentivirus.
Mycoplasma Removal Treatment Protocols v2
Authors: Lopez Carolina
Published: August 2024

This protocol describes three mycoplasma removal procedures to be utilized depending on need. The protocols are described from milder/maintenance to the harshest option to be used in extreme cases of contamination when it is not possible ato re-start the culture from a clear source.
Protocol for RNA Extraction from Peanut Samples Using Direct-zol™ RNA Miniprep v1
Authors: Gabriela Paredes Gabriela
Published: August 2024

RNA extraction is a fundamental step in molecular biology, crucial for downstream applications such as qPCR, sequencing, and gene expression analysis. The process of RNA extraction involves the isolation of RNA from cells or tissues, which must be done in a way that preserves the integrity and purity of the RNA. This is especially important because RNA is highly susceptible to degradation by RNases, which are ubiquitous in the environment. The extraction process typically involves several key steps: cell lysis, removal of proteins and other contaminants, and purification of the RNA. The Direct-zol‱ RNA Miniprep kit simplifies these steps by allowing for the direct processing of samples in TRIzol‱ or similar reagents, which are known for their strong denaturing properties that inactivate RNases and other degradative enzymes. TRIzol‱ is particularly advantageous for samples with high oil content, such as peanut seeds, as it effectively disrupts the cell membranes and separates nucleic acids from lipids and other cellular components without the need for chloroform, phase separation, or precipitation steps. Using TRIzol‱ in combination with the Direct-zol‱ RNA Miniprep kit ensures that high-quality total RNA, including small RNAs, can be efficiently extracted even from challenging samples like peanut tissues. This streamlined method reduces the complexity and time required for RNA extraction, making it an ideal choice for researchers working with oil-rich seeds.
[RETRACTED] CrossRef Outage Prep, citations and versions the third copy v1
Authors: Frolov Vladimir
Published: August 2024

[RETRACTED]

Description example
“Collorindo” as páginas da revista Veja. As narrativas e as imagens sobre o movimento dos caras-pintadas
Authors:   Universidade Católica de Pelotas, Ferreira dos Santos Douglas , Barcellos Dias Carolina Kesser ,   Universidade Católica de Pelotas, da Silva Della Vechia Renato ,   Universidade Católica de Pelotas
Published: August 2024

Este artigo discute a representação visual e textual do Movimento dos Caras-pintadas nas edições da revista Veja publicadas ao longo de 1992. Por meio da análise das fotografias, manchetes e textos da Seção Brasil, procurou-se compreender como a revista – um produto mercadológico que interfere na construção da representação sobre o passado brasileiro – construiu as narrativas que legitimaram as manifestações contrárias ao governo Collor, cristalizando-as no imaginário social como um modelo de participação política, embora suavizando seu conteúdo de contestação, restringindo-as a uma ideia de ética na política.
A prospective observational study on efficacy of ulipristal acetate in treatment of uterine fibroids
Authors: Singh Eshna , Khanijo Vandana , Unni Jyothi
Published: August 2024

Background: Uterine fibroids are common benign tumors where management has traditionally been surgical.  Ulipristal acetate (UPA) is a new, effective, and well-tolerated option for the preoperative treatment of moderate and severe symptoms of uterine fibroids. Objectives were to study the utility of UPA in treatment of uterine fibroids.
Methods: A prospective observational study was conducted in women aged 18-50 years presenting with menstrual abnormalities with fibroids to Jehangir Hospital, from 01 December 2017 to 30 September 2019. The 50 premenopausal women with at least one fibroid ≥3 cm in diameter and <8 cm, with heavy menstrual bleeding (HMB) or pain were included. 5 mg of UPA was given once daily for a period 3 months. Primary outcome was to determine symptomatic relief.
Results: Uterine bleeding was controlled in 96% patients whereas 100% had pain relief. Reduction of fibroid volume and size was noted in 60% patients. Favourable outcomes were seen in more cases of intramural fibroids as compared to sub-serosal and submucosal fibroids.
Conclusions: UPA proved to be an effective drug for symptomatic relief in patients with uterine fibroids. Although 60% patients showed reduction in fibroid size, the amount of reduction was not very significant in most of the patients.
Determinants impacting the quality of life in postmenopausal women: an in-depth narrative review
Authors: Yemde Awanti , Kawthalkar Anjali , Bhalerao Anuja
Published: August 2024

The menopausal transition represents a pivotal phase in women's lives, marked by intricate physical, psychological, and social changes that collectively shape their quality of life (QoL). Postmenopausal women, characterized by the cessation of menstrual cycles and declining ovarian hormone production, experience a convergence of multifaceted influences during this critical period. This review aims to comprehensively explore and describe the factors impacting the QoL of postmenopausal women, offering valuable insights for healthcare practitioners, policymakers, and researchers seeking to enhance well-being in this life stage. In this descriptive review, the existing literature on postmenopausal women's QoL determinants is examined to provide a detailed understanding of the various contributing factors. The complex interplay of hormonal shifts, psychosocial dynamics, socioeconomic conditions, health status, and lifestyle choices intricately shapes the postmenopausal experience. These factors, whether independently or interactively, play a crucial role in defining the trajectory of postmenopausal QoL. A thorough exploration of available studies from various databases such as PubMed, Scopus, and PsycINFO was conducted. Relevant articles were identified through a combination of keyword searches and manual screening, focusing on studies that discuss the determinants of QoL in postmenopausal women. From a substantial initial pool, six key articles were selected based on their relevance and contribution to understanding the topic. Through this descriptive review, several key factors were identified as influential in shaping postmenopausal QoL. Hormonal changes, education level, lifestyle choices, attitudes towards menopause, self-perceived efficacy, family dynamics, menopause-related symptoms, and socioeconomic indicators emerged as significant determinants. Particularly, vasomotor and sexual symptoms were found to have a substantial impact on well-being across various dimensions. The review also highlighted the importance of targeted interventions to address specific facets of QoL in postmenopausal women, offering potential pathways for enhancing overall well-being during this life stage.
Creating a Revolutionary History of the Soviet East: the Turkestan Uprising of 1916 in Soviet Historiography and Propaganda of the 1920s and 1940s
Authors: Tikhonov Vitaliy
Published: August 2024

The article analyzes the contexts of the formation and development of the image of the Turkestan uprising of 1916 in Soviet historical science and propaganda of the 1920s and 1940s. The work uses both published and unpublished sources. In particular, an unpublished monograph by A.V. Shestakov is being introduced into scientific circulation. It is demonstrated that the uprising was firmly embedded in the class-anti-colonial discourse of the Soviet historical narrative, fulfilling the function of constructing the revolutionary history of Central Asia and building its continuity with the October Revolution. It is indicated that the foreign policy factor played a significant role in updating the image of the uprising, since the Soviet government considered the uprising as a mobilizing image for the colonial-dependent peoples. Despite the revision of the evaluation of the anti-Tsarist uprisings in the 1940s, the Turkestan uprising retained its position in the official policy of memory, since it opposed the “idealization of the feudal past” and supported the all-Union revolutionary myth.
How the British Tried to Turn the Russian North into a Colony
Authors: Labutina Tatyana
Published: August 2024

The article deals with the British attempt to colonize the northern region of the Russian state during the period of Troubles. This problem, despite its relevance and scientific significance, remains poorly studied in modern Russian and practically unexplored in British historiography. The author pays special attention to the study of the plans of the British government to colonize, seize Russian territories, change the form of government in Russia, and finance the operation at the expense of the local population. The colonization plan proposed by the military (Thomas Chamberlain, Captain J. Margeret) was discussed at a meeting of the Privy Council of the Kingdom under the leadership of King James I Stuart. However, while preparations were underway for a military invasion, Tsar Mikhail Romanov, elected by the people, took the Russian throne, and the Troubles were over. As a result, the British plans to turn Russia into their colony were not destined to come true.
“The Tyrant Has no Right to the Crown of France”: Strategies of National Identification of the French in the Political Discourse of the 15th Century
Authors: Tsaturova Susanna
Published: August 2024

The article analyzes French political treatises of the first half of the 15th century, written in the camp of supporters of Charles of Valois to justify his rights to the throne of France and against the treaty of Troyes in 1420 on the “union of the two crowns”. The defenders of the interests of the Dauphin Charles used, first of all, legal arguments: violation by this treaty of the ancient Salic law prohibiting the transfer of the throne in France through the female line; deviation from the rules and customs of succession to the French throne established by royal acts. Special emphasis was placed on the requirement to be loyal to the "natural" sovereign, based on the concept of the laws of nature as a Divine institution. The article pays close attention to anti-English invectives and the negative image of the British. Historians ignored this conspicuous and regularly recurring motif or regarded chauvinism and xenophobia as unworthy of scientists and intellectuals. The author of the article suggests interpreting these passages in the context of the legal concept of loyalty built by the ideologists of the monarchy. In political treatises, the kings of England are condemned for disloyalty: Edward III for the war he started against his liege, the king of France, and Henry of Lancaster for the removal and murder of King Richard II. Because of this, English kings are qualified in French political treatises as tyrants and usurpers. But the English, in general, are exposed in these treatises as a cruel and disloyal people to their kings, whom they are ready to displace on a whim. These qualities of the British and their monarchs are designed to shade and emphasize the loyalty of the French as their special national virtue. Thus, in the French political discourse, loyalty is closely connected with national identity. And this mythologeme is firmly embedded in the French monarchist ideology.
Typology of Multiple Polities in the Antiquarian Discourse
Authors: Palamarchuk Anastasia
Published: August 2024

In the Antiquarian discourse of the early 17th century two descriptive models and correlating contexts were used for describing structural complexity of states and polities. Nearly every polity described by antiquaries was represented as structurally complex, or, in K. Russel’s expression, “multiple”. The first model which can be characterized as “hierarchical”, directly corresponded to the traditional order of precedence of feudal titles and dignities and had explicit outward focus. This model reflected the necessity to reflect on corresponding status of existing monarchies of Christian oikumene and allowed to set out universal criteria which allowed to identify the status of a monarchy. The inward focus was characteristic of the second descriptive model. It allowed to demonstrate internal integrity of local communities, which used to be a part of larger polities during their history.
“In Kiev, There Were Sitting the Men”: a New Reconstruction of the Dynastic Conflict between Yaroslav and Mstislav, Sons of Vladimir Svyatoslavich
Authors: Vinogradov Andrey
Published: August 2024

The article analyses the last episode of the internecine war between the sons of the Kiev prince Vladimir Svyatoslavich — the confrontation in 1024—1026 between Yaroslav (“the Wise”) and Mstislav. It has repeatedly become the object of attention of researchers, but many questions still remain controversial and unclear. The main problem is unclearness of the story about these events in the main source — “The Tale of Bygone Years”. According to it, despite the fact that after the victory in the Battle of Listven in 1024 Mstislav allegedly ceded Kiev to Yaroslav, the latter did not dare to come there and ruled Kiev through members of his retinue. On the basis of various sources (a Scandinavian saga, the Annals by the Polish chronicler Jan Długosz written in Latin, Old Rus princely seals) the authors come to the following conclusions. The Kiev prince in 1024—1026 was most likely Mstislav Vladimirovich, not Yaroslav. Ιn favour of this is speaks, in particular, the Mstislav’s adoption of title μέγας ἄρχων Ῥωσίας, which was later adopted by Yaroslav, but then stopped to be used. The tendency of the Russian chronicle was probably determined by a desire to soften the conflict character of the relations between the two positive heroes of the narrative after the sudden appearance of Mstislav in Southern Rus. As a result, logical inconsistencies and silence about some important events in the “The Tale of Bygone Years”, were connected not so much with its later editing as with the original contradictory rhetorical strategy of the autor of the annalistic narrative. In addition, new finds of Mstislav’s seals confirm that his saint patron was Constantine the Great.
Where Is the Limit of Loyalty? On a Monarchical Impostor and a King on the Throne
Authors: Gershtein Anna
Published: August 2024

Monarchical impostor usually opposed himself to ruler sitting on a throne. People who went over his side refused the loyalty to the official authority when recognized an impostor as a real power. However, the false Frederick II of Hohenstaufen in 1285 offered the legitimate King Rudolf I of Habsburg a different, non-alternative project, but a unifying one. The impostor appealed to the King to come to him at the Reichstag and receive the German lands from him as an «Emperor». This was an attempt to take his place in the political arena without setting a goal (at least in the beginning) to remove Rudolf. The notion of loyalty to the King in such circumstances turns out not to be strictly alternate, but more flexible, variable depending on the historical context. The interpretation of the actions of the self-proclaimed Emperor as loyalty or disloyalty to Rudolf depends primarily on the interpretation of the main political and military force — the King.
Satisfaction with Distance Learning: an Analysis through Graduates at UFSM
Authors: Pontes Vanessa da Silva , Vieira Kelmara , Matheis Taiane Keila , Bender Filho Reisoli , Ribeiro Victor Matheus Portela
Published: August 2024

This study analyzed how pleased graduate students are in courses offered by Open University of Brazil, Santa Maria University (UFSM). Methodologically, we applied descriptive statistics, factor analysis and regression in a sample of 712 graduates. Results showed that graduates are satisfied with the chosen course and indicated that the main determinant is related to the quality of teaching. Conversely, satisfaction was lower for non-white graduates, which included cultural and social issues related to black ethnicity, and for those who, at some point during the course, thought about dropping out. It is expected that the knowledge of the determinants of graduates’ (dis)satisfaction may contribute to the settlement of strategies that aim to increase students’ satisfaction and the retention levels.
 
Keywords: Distance learning. Degree of student satisfaction. Graduates. Higher education.
Gamificação como Estratégia de Ensino-Aprendizagem Ativa sobre Obesidade e Hábitos Alimentares Saudáveis para Adultos e Pessoas Idosas
Authors: Kaya Andreia Naomi Madoz , Garcia Kerolyn Ramos , Pimenta Bruna Cabral Reis , Santos Samara Rosa Pessoa dos , Karnikowski Margô Gomes de Oliveira , Pereira Leonardo Costa , Gris Eliana Fortes
Published: August 2024

A gamificação proporciona estratégias para engajar e motivar o ensino de diversas áreas e torna-se importante nos dias atuais por conta do avanço da tecnologia e a necessidade de novas ferramentas de ensino-aprendizagem. O objetivo do presente estudo foi analisar o efeito do uso da gamificação como estratégia de ensino-aprendizagem, por meio da aplicação de um jogo educacional em formato de quiz, para população adulta e idosa. Com isso foi realizado um estudo quali-quantitativo envolvendo grupo intervenção (GI) e grupo controle (GC), com participantes do Programa Universidade do Envelhecer da Universidade de Brasília (UniSER/UnB). Os instrumentos utilizados para coleta de dados foram formulários iguais aplicados pré e pós aplicação das metodologias, de modo que no GI foi a utilizado o jogo/game e no GC foi a aula tradicional. Os resultados mostraram que os participantes que tiveram aulas gamificadas tiveram a percepção de aumento do conhecimento, bem como foi observada pela análise qualitativa a citação de termos corretos sobre o assunto.
Digital Zakat and the Role of Zakat Intermediation: Case Study at BAZNAS West Java
Authors: Fadilah Sri , Rosdiana Yuni , Sundaya Yuhka , Maemunah Mey , Fitriah Epi , Lestari Rini , Hernawati Nopi
Published: August 2024

This study aims to determine the relationship between the use of digital zakat and the intermediary role of zakat in zakat institutions. The background of the research starts from the zakat institution which is authorized by the government according to Law Number 23 of 2011 concerning the management of zakat in Indonesia which carries out the role of zakat intermediary, namely collecting funds from muzaki and distributes to mustahiq. In fact, there is less than optimal collection of zakat with low realization of collection and less effectiveness of zakat distribution. Allegedly many factors are considered to be the cause of the ineffectiveness of the intermediary role of zakat, namely the collection and distribution of zakat. In this article, it is explained that the implementation of digital zakat is considered as one of the factors that has become an obstacle. The research method used is a case study at zakat institutions at the provincial level in the city of Bandung, namely BAZNAS West Java. Variables of research are digital zakat and the role of intermediation. Data collection were done by performing interviews and documentation. The results of the study show that the implementation of digital zakat at zakat institutions can optimize zakat collection with evidence of increased collection and more effective distribution of zakat, especially related to performance achievements.
Keywords: digital zakat, effectiveness, optimization of collection
Policy Constraints on Local Governance for Community Resilience: Qualitative Insights from Stakeholders in Disaster-prone Areas
Authors: Yuniarti Y , Respati T. , Januarita R. , Irasanti S. N.
Published: August 2024

This qualitative study examines the impact of central government policies on community resilience for disaster preparedness, explicitly focusing on the constraints faced by local governments. This study explores the challenges hindering optimal performance at the local level through 18 informants using focus group discussions with key stakeholders, including sub-district heads and village leaders. The findings reveal that central government policies pose significant hurdles to local governance in disaster-prone areas. These policies restrict local governments’ decision-making authority and autonomy, impeding their ability to respond effectively to disaster risks and emergencies. Notably, the study highlights the presence of a communityled disaster management organization already in place, comprising members from within the community. The policy constraints identified include limited resource allocation, bureaucratic procedures, and a need for more flexibility in decision making. Stakeholders express concerns regarding rigid central government frameworks that do not recognize or account for the unique needs of individual communities. The study emphasizes the importance of policy reforms to empower and support local governments and their existing disaster management organizations. This research contributes to understanding community resilience by highlighting the vital role of local governance and community-led organizations in disaster preparedness.
Keywords: community, disaster, government policies, resilience
Building Entrepreneurial Networks for Omnichannel Coffee Retailing in Cimenyan Sub-district: A Case Study
Authors: Djamaludin D , Achiraeniwati Eri , Rejeki Yanti Sri , Rukmana Otong , Muhammad Chaznin R.
Published: August 2024

Cimenyan district in Bandung Regency, enriched with coffee farms, contributes around 8 quintals annually to Bandung’s 21.53 tons of coffee yield. As a distinguished coffee-producing hub in Indonesia and globally, it is vital in coffee trade dynamics. Discussions with local coffee stakeholders unveiled challenges in Cimenyan’s coffee value chain, like seed quality enhancement, post-harvest processing, and traditional marketing practices. This initiative aims to bolster entrepreneurs and coffee growers in Cimenyan, focusing on expanding their market reach through an omnichannel retail strategy empowered by digital technology, notably incorporating Big Channel software training. This software training is crucial for orchestrating omnichannel retail operations, providing a platform for sales diversification. By facilitating knowledge transfer, skill enhancement through software training, and necessary support, it is envisioned that local stakeholders will broaden their sales across diverse digital platforms, enriching the customer journey from product exploration to purchase. The endeavor seeks to augment coffee sales competitiveness, foster innovative entrepreneurship, and/or extend digital and offline channels in the existing business domain, thereby, creating a more robust and technologically adept coffee retailing network in the Cimenyan district.
Keywords: entrepreneurial capacity enhancement, omni channel retail, coffee production, Cimenyan District
Strategies to Achieve Sustainable Development Goals through Diversification of Waqf Products
Authors: Amaliah Ima , Aspiranti Tasya , Shaharuddin Amir
Published: August 2024

Waqf can be used to achieve SDGs. This is evident from the programs rolled out by waqf institutions that have covered several articles in the SDGs, but in fact, they still revolve around the same articles such as no poverty, inequality, health, education, gender, clean water, and sanitation. Therefore, it is important to map the diversification of waqf products so that a waqf diversification strategy can be developed for SDG’s implementation. The method used is descriptive quantitative using data from the annual reports of waqf BSI, Sinergy Foundation, and OJK roadmap. The results of the study show that there are similarities in waqf diversification between waqf institutions where waqf institutions have implemented 6-9 waqf articles (eradicating poverty, ending hunger, good health and well-being, quality education, gender equality, access to clean water and sanitation, clean and affordable energy). Therefore, it is necessary to transform waqf institutions, laws and procedures, digital transformation, and literacy and education.
Keywords: diversification strategy, SDG’s, Waqf program
Environmental Control and Management Continuation through the Ruling of the State Administrative Court
Authors: Latif Abdul , Cahyaningrum Lulik Tri
Published: August 2024

Changes in environmental law provisions that have the potential to cause inconsistencies in these decisions must be harmonized with the legal system. Without consistency in decisions regarding environmental public administration disputes, it will be difficult for the government to make decisions and guidelines for determining policies related to environmental protection and management. This research aims to determine the consistency of environmental administration dispute decisions in state administrative courts. The writing method uses a normative juridical approach with statutory regulations, the legal sources used were primary and secondary relating to state administrative law and environmental regulations, apart from that the author uses a case study approach. The results of the research show that the implementation of regulations related to state administrative decisions in the environmental sector is still inconsistent, with the government placing more emphasis on remedial (retroactive) efforts in environmental problems, manifested in the form of government intervention to restore environmental conditions after pollution and/or damage that occurs to the environment. Considering that the majority of environmental law enforcement is in the field of government administration, inconsistencies in environmental state administration decisions must be resolved immediately to realize good environmental protection and management. In fact, the decision of the state administrative court judge is not only intended to resolve a dispute but will also serve as a guideline for government agencies/officials in realizing sustainable environmental protection and management.
Keywords: consistency, environment, protection, sustainability
Scoping Review: Pentahelix Community Empowerment Development Strategy as an Effort to Improve the Quality of Life during the Covid-19 Pandemic in Low Middle Income Countries LMIC
Authors: Nurlatif Rr. Vita , Kushermanto Andi , Isrofah I , Priharwanti Ardiana , Prasetyo Eko Budi
Published: August 2024

The Covid-19 pandemic has had a multi-sectoral impact not only on the health sector, but also on multi-sectors, such as health, education, economy, and other crucial and supporting sectors. During the pandemic, that hit more than 200 countries, various community empowerment strategies have emerged, all of which have the same pattern, namely stakeholder engagement. The community empowerment strategy, which aims at improving the quality of life based on family is the way out or the most possible way out to improve public health status during the new normal, especially in middle and lower countries. A systematic approach was taken to search for literature using the PubMed DataBase, Health Evidence, Cochrane, and Science Direct. Then the results of empirical research that met the criteria were carried out using critical analysis based on the PCC (Population, Concept, and Context) approach, using the keywords ((((community) health empowerment) OR (health empowerment)) OR (Community health development)) OR (Stakeholder engagement)) AND (((Community empowerment development strategy)) OR (Community development strategy))) AND (((Improving the quality of live based on Thought families The Age of New Habits)) OR (quality of live)) OR (Improving quality of live family based)))) AND (Low Middle Income Country). The results are based on the results of a scoping review of 9 articles, five models of pentahelix community empowerment strategies were obtained as an effort to improve the quality of life during a pandemic in lower middle-class countries. Suggestions for the involvement of stakeholders and the community are key factors that must always be synergized as a way out of community empowerment during a pandemic.
Keywords: stakeholder engagement, quality of life, new habits, low middle-income country
Determinant of Financial Distress in Conventional Rural Banks in Central Java: Before and during Covid-19 Period
Authors: Kushermanto Andi , Rahayu Titi , Kurnianingsih Helen , Ulum Akhmad Samsul , Fachrur M. Maulidin , Alisa Inayah Risqi
Published: August 2024

Financial distress refers to a state in which a company is unable to generate sufficient income and has difficulty paying its debt, and this effect can threaten the company’s financial condition towards bankruptcy. This study aims to examine the influence of loan-to-deposit ratio, nonperforming loans, and return on assets on financial distress. Additionally, it conducts multigroup testing of these variables in the Covid-19 pandemic period. The population of this study is conventional rural banks in Central Java for the 2019–2020 period. The sample, consisting of 84 observations, was obtained using the purposive sampling method. The data analysis technique employed in this study is Partial Least Squares-Structural Equation Modeling (PLS-SEM), utilizing WarpPLS version 8.0 software. This study shows that loan-to-deposit ratio and nonperforming loans have a positive effect on financial distress, while return on assets has a negative effect on financial distress. Furthermore, the additional analysis shows that there are significant differences between the loan-to-deposit ratio and nonperforming loans on financial distress in the pre-Covid-19 period and during the Covid-19 period. However, there is no significant difference in the effect of return on assets on financial distress in these Covid-19 periods.
Keywords: covid-19, financial distress, loan to deposit ratio, nonperforming loans, return on asset
Cinnamon Flour Enriched Commercial Feed (Burmese Cinnamon) With Different Dosage on the Growth of Cantang Group Fish (Ephinephelus Fuscoguttatus X Lanceolatus)
Authors: Syakirin M. Bahrus , Soeprapto Hayati , Mardianan Tri Yusufi , Linayati L , Aziz Bagus Kuncoro
Published: August 2024

The cantang grouper is the result of a cross between the tiger grouper and the kertang grouper (Ephinephelus fuscoguttatus x lanceolatus). It inhabits the bottom of tropical and subtropical sea waters, typically solitary, but forms groups when spawning, and is nocturnal. The selling price is quite expensive which makes it attractive. The purpose of this study was to determine the effect of adding cinnamon flour at different doses to commercial feed on the growth of cantang grouper. This study employed a quantitative experimental approach. The experimental design adopted was Completely Randomized Design (CRD), consisting of 4 treatments, each replicated 3 times. Parameters observed included Feed Conversion Ratio (FCR) value, the highest value was in treatment A and the lowest was in treatment B, namely in the treatment of giving cinnamon flour 0.5 g/100 g of feed. The survival rate of cantang grouper was notably high, with an average of 100% throughout the duration of the study. The addition of cinnamon powder in feed had a very significant effect on the growth of cantang grouper. The most substantial growth was observed in treatment B, where cinnamon powder was added at a rate of 0.5 g/100 g of feed, resulting in an average growth of 4.68 grams. The study of cantang grouper was supported by water quality parameters (DO, pH, turbidity, salinity), which remained conducive for the maintenance of cantang grouper juveniles.
Keywords: cantang grouper, water quality, growth
Self-Management Mentoring Model in Improving the Health Quality of Life of Productive Age Diabetics
Authors: Nurlatif Rr. Vita , ‎ Sumardiyono , Rahardjo Setyo Sri
Published: August 2024

Diabetes is a global epidemic, and failure to address it directly and effectively can lead to economic losses affecting countries in Asia and Africa. This systematic review was compiled to find a comprehensive self-management mentoring model by community health workers that have an impact on improving the quality of life. The search strategy for articles and data sources encompassed various electronic databases, including PubMed, Health evidence, Cochrane, Google Scholar, Web of Science, Publish and Perish. The search strategy utilized PICOT key ((((diabetes mellitus[Title/Abstract] OR diabetes management by peers [Title/Abstract])) AND (control[Title/Abstract] OR no[Title/Abstract])) AND (HQOL[Title/Abstract] OR QOL[Title/Abstract] OR HBA1C[Title/Abstract] OR blood pressure[Title/Abstract] OR Body mass index[Title/Abstract])) AND (week[Title/Abstract] OR month[Title/Abstract]) . Based on the searching results obtained 277 articles found, following screening, extraction, and Full-text review, 10 articles were synthesized, various models of self-management were obtained with peer assistance and community health workers, such as PBE, IBE, PBS, HE, HC, Model 5 healthy lifestyle, self-management with CHW mentoring for 3 months. COMP-DSMP Model for 3 months. Diabetes Online Model for diet & e-health for diabetics, “Blue Star Mobile Apps” Model, DSME DMT2 Model. The success of self-management is highly dependent on the amount of motivation of diabetes mellitus (DM) patients to improve their knowledge, attitudes, and practices in controlling and managing blood glucose control. Compliance with therapy, physical activity, control of sugar consumption, dietary management, stress management, and regulation of rest patterns are the keys to optimal quality of life for people with diabetes mellitus.
Keywords: community health worker, health quality of life, self-management mentoring
Reimaging Solidarity Feminist of Jesus in the Gospel of John 4:1-42 as Implications of Church Solidarity toward Women
Authors: ‎ Darius
Published: August 2024

One major concern of the freedom movement is the issue of feminism. Feminism movements exist to attack all acts of injustice toward women. Therefore, feminism is an effort or movement for women who demand emancipation, equality, and justice between the rights of men and women. This study describes the concept of Jesus’ feminist social solidarity in the Gospel of John 4:1–45 as a reflection of the church in applying feminist solidarity in various contexts. Therefore, the reflection of Jesus’ feminist solidarity is the basis for the church to maintain a balance between men and women, especially in service. The study utilizes the sociology hermeneutics and feminist hermeneutics approaches, both of which were carried out in an analytical descriptive manner. Sociological hermeneutics was used in the text of John 4:1–42 to analyze the sociological character of each of the characters in the text.1 Apart from that, feminist hermeneutics was applied to the text John 4:1–42 to reinterpret it in the light of the feminist movement to produce feminist solidarity centered on the feminist perspective of Jesus. The findings of the study show that: (1) Jesus’ outreach has destroyed the separator and lifted the degree of strata of Samaritan women’s society; (2) the kindness of Jesus is evidence of outreach to marginalized (women) groups; and (3) the feminist perspective of Jesus is empowering namely having become a Samaritan woman as a tool for Jesus to reach out.
Keywords: solidarity, feminism, Gospel, Jesus, movement
Jurisdiction of Russian Commercial Courts over Cases on Bankruptcy of Foreign Companies
Authors:   Associate Professor of the Department of Civil Procedure of the Ural State, Razdyakonov Evgeny S.
Published: August 2024

The article examines the issue of changing the approach to the interpretation of the law on the competence of Russian courts to consider cases of insolvency (bankruptcy) of foreign companies. It is noted that in the absence of changes in legal regulation, the new approach is due to the law enforcement activities of arbitration courts. Based on the provisions of the latest judicial practice, the author formulates the key elements of the competence of arbitration courts to consider bankruptcy cases of foreign companies.
Recognition of Notarized Powers of Attorney Issued in the FRG by Russian Notaries
Authors:   Associate Professor of the Department of Civil Procedure of the Ural State Law, Bessonova Anastasiia I.
Published: August 2024

The article analyzes the problems of recognition (assessment) of foreign notarial acts by Russian notaries using the example of notarized powers of attorney certified by notaries in Germany. Attention is drawn to the importance of correct application by notaries of the rules of international private law to the form and content of foreign powers of attorney.
The Required Forum for International Inheritance Cases: What's Next?
Authors:   Professor of the Department of Civil Procedure of the Ural State Law University named after V.F. Yakovlev, Rents Igor G , Zazulina Liubov D. ,   Postgraduate Student of the Department of Civil Procedure of the Ural State
Published: August 2024

State Law University named after V. F. Yakovlev The article is devoted to the expansion of the competence of Russian notaries and courts in international inheritance cases as a result of the adoption of the decision of the Constitutional Court. The deviation authorized by him from the connectedness of the inheritance procedure and the applicable law conceals the potential to increase the efficiency, speed and convenience of settling the Russian part of the cross-border inheritance, but does not exclude serious complications that threaten the stability and predictability of inheritance. Based on the analysis of possible consequences, the conclusion is drawn about the exclusivity of the application of the doctrine of the necessary forum in the current conditions and the need to develop a universal approach to the delimitation of jurisdiction in cross-border inheritance.
Mide kanserinde adropin ve hipoksi ile indüklenebilir faktör -1 alfa’nın önemi
Authors: Çağlar Alperen Akansel , Hannarici Zekeriya , Büyükbayram Mehmet Emin , Turhan Aykut , Çoban Eşdur Pınar , Eğilmez Esra , Kızıltunç Çağrı , Bilici Mehmet , Tekin Salim Başol
Published: August 2024

Amaç: Mide kanseri tüm dünyada ki yeni kanser vakalarının %5,6’sını oluşturur ve beşinci en sık görülen kanser türüdür. Kansere bağlı ölüm sıralamasında ise üçüncü sırada yer almaktadır. Lokalileri mide kanserinde, günümüzde ki standart neoadjuvan tedavi ile hastaların yalaşık % 75’ine uygun rezeksiyon yapılabilmektedir. Hastaların iki yıllık hayatta kalma oranları yaklaşık %70 iken bu oran beşinci yılda %45’lere düşmektedir. Bir çok kanser türünde erken tanı ile yüksek küratif tedavi oranları ve uzun süreli sağkalım başarısı sağlanmasına rağmen mide kanseri için malesef aynı durum sözkonusu değildir ve karşılanmamış tedavi ihtiyacı devam etmektedir.
Adropin, vücudumuzda birçok dokudan salgılanan; başlıca enerji homeostazisi, anjiyogenez, hücre proliferasyonu ve hücre göçü süreçlerinde düzenleyici rolü olan bir peptittir. Hipoksi ile indükenebilir faktör (HIF) ise dokularda oksijen seviyeleri düşünce aktive olur ve hücrelerin büyümesi, gelişmesi ve farklılaşmasını regüle eder.
Yeni tanı almış lokal ileri mide kanseri hastalarında ki adropin ve HIF-1α sevyeleri ile sağlıklı bireylerdeki adropin ve HIF1-α seviyeleri karşılaştırılarak, adropinin ve HIF1-α’nın mide kanseri patogenezi üzerinde rolü ve tedavi yanıt oranlarının adropin ve HIF-1α seviyeleri ile ilişkisinin araştırılması amacıyla prosektif bir çalışma planlandı.
Gereç ve Yöntemler: Yeni tanı almış, neoadjuvan kemoterapi alacak olan lokalileri mide kanserli hastalar ve sağlıklı kontrol grubu arasında adropin ve HIF-1α düzeyleri karşılaştırıldı. Ayrıca tedaviyi tamamlayan hastalarda klinik ve patolojik yanıt oranları ile adropin ve HIF-1α düzeyleri arasında bir ilişki olup olmadığına bakıldı.
Bulgular: Adropin, mide kanserli hastalarda istatistiksel anlamlı olarak daha düşük, HIF-1α düzeyleri ise mide kanserli hastalarda istatistiksel anlamlı olarak daha yüksek bulundu. Adropin ve HIF-1α düzeyleri ile klinik yanıt, patolojik yanıt, operabilite durumu, yeni patolojik T (ypT) ve yeni patolojik N (ypN) evreleri gibi çeşitli klinik değişkenler arasında anlamlı bir farklılık görülmedi.
Sonuç: Daha önce araştırılmamış olan ve literatür taraması yoluyla herhangi bir veri tespit edilemeyen adropin ve mide kanseri arasındaki ilişkiyi ortaya koymak önemliydi. Adropin ve HIF-1α'nın mide kanserinde rol oynayan iki önemli faktör olduğu açıktır. Ayrıca adropin ve HIF-1α mide kanserinin erken teşhisi için iki önemli parametre olabilir. Adropin ve HIF-1α'nın mide kanserindeki rolünü aydınlatmak için daha fazla çalışmaya ihtiyaç vardır.