bluuebunny/crossref_metadata_2025 huggingface dataset:
Metodología de síntesis de autómatas para controlar sistemas de navegación autónoma terrestre
Authors: Martínez Valencia Jorge Luis , Holguín Londoño Mauricio , Holguín Londoño Germán Andrés
Published: July 2024

En este trabajo se plantea una metodología para la síntesis de autómatas en aplicaciones de navegación autónoma terrestre con una tarea global. La metodología propuesta se basa en el diseño de autómatas por gramáticas regulares y permite generar una política de control para la conducción autónoma de un vehículo en un ambiente parcialmente controlado mientras se extrae información del entorno a través de sensores. Además, se plantean los inconvenientes que se presentan al tratar de abordar esta aplicación con enfoques tradicionales que implican la síntesis de autómatas finitos no deterministas. Por último, se presentan losautómatas obtenidos al validar la metodología propuesta a través de simulaciones utilizando el software MATLAB con el Toolbox integrado de realidad virtual (V-Realm Builder).
Teaching Quantitative Methods For Social Anthropology: Reflections and recommendations from student experiences
Authors: Rohmann Anna , Kinsell Hannah , Ramadhita Sarah
Published: July 2024

Training in quantitative methods is an essential part of postgraduate degree courses in social anthropology. However, the student experience with learning these methods is negative and it is not perceived useful to studies and future professional practice. That is why we ask how skills in quantitative methods serve social anthropologists and what challenges to teaching need to be addressed. We use autoethnographic reflections and self-narratives to illustrate how our recommendations are situated in the student experience. Our goal is to contribute to discussions around multimodal, interdisciplinary approaches in social anthropology and to improve the student experience with quantitative method modules. To make this tangible, we give six recommendations: 1) focus on data literacy, 2) make quantitative concepts applicable to research practice, 3) situate quantitative methods in social anthropology, 4) address quantitative methods problematic aspects, 5) introduce it with care, and 6) facilitate collaborative learning and peer-support.
The Craft of Teaching. Cultivating Uncertainty and Moving in Playfulness as Pedagogical Strategy
Authors: Arantes Lydia
Published: July 2024

I have long tried to move away from teaching as “passing on knowledge” and moved towards practicing teaching as co-creating knowledge. I have come to regard teaching as a joint act of exploration, also taking into account students’ everyday life experiences. In the last academic year, I decided to expand my pedagogy by including playfulness. This required openness and vulnerability on behalf of me as the person developing the course as well as a new kind of engagement and involvement on behalf of my students. In doing so, the courses opened up space for making visible “epistemological journeys” (Arantes, 2021) and “liminal knowledges” (Burgos-Martinez, 2018). In this paper I give insights into some of the chosen approaches – of which a few involved playing with the idiom ‘business before pleasure’ – and reflect on their implications. I suggest that anthropology not only move within playfulness in the realm of research and representation but also on the level of teaching. Ultimately, I also reflect on what learning and teaching playfully and giving space to homo ludens (Huizinga, 1950) can teach us about the broader role of play for anthropology.
Cryopreservation of stem cell-derived beta-like cells enriches for insulin-producing cells with improved function
Authors: Barra Jessie M. , Kratz Austin T. , Castro-Gutierrez Roberto , Proia James , Bhardwaj Gurprit , Phelps Ed , Russ Holger A.
Published: July 2024

The generation of stem cell-derived beta-like cells (sBC) holds extreme promise as not only an abundant insulin-producing cell source for replacement therapy of Type 1 diabetes (T1D), but also as an invaluable model system for investigating human beta cell development, immunogenicity, and function. Several groups have developed methodology to direct differentiate human pluripotent stem cells into pancreatic cell populations that include glucose responsive sBC. Nevertheless, the process of generating sBC poses significant experimental challenges. It involves lengthy differentiation periods, experiences substantial variability in efficiency, and inconsistencies in obtaining functional sBC. Here, we described a simple and effective cryopreservation approach for sBC cultures that yields homogeneous sBC clusters that are enriched for insulin expressing cells while simultaneous depleting proliferative progenitors. Thawed sBC display enhanced glucose-stimulated insulin release compared to controls in vitro and can effectively engraft and function in vivo. Collectively, this approach alleviates current challenges with inefficient and variable sBC generation while improving their functional state. We anticipate that these findings can inform ongoing clinical application of sBC for the treatment of patients with T1D and serve as an important resource for the wider diabetes field that will allow for accelerated research discoveries.
No evidence for persistent enteroviral B infection of pancreatic islets in type 1 diabetic and pre-diabetic patients from RNA-Seq data
Authors: Manduchi Elisabetta , C. Descamps Hélène , Schug Jonathan , Da Tong , Lahori Deeksha , El-Mekkoussi Hilana , R. Betts Michael , H. Kaestner Klaus
Published: July 2024

Abstract

Persistent enterovirus B infection has been proposed as an important contributor to the etiology of type 1 diabetes. We leveraged extensive bulk RNA-sequencing data from alpha, beta, and exocrine cells, as well as single cell islet RNA-Seq data from the Human Pancreas Analysis Program (HPAP), to evaluate the presence of enterovirus B sequences in the pancreas of type 1 diabetic and pre-diabetic (non-diabetic but auto-antibody positive) patients. We examined all available HPAP data for either assay type, including non-diabetic, type 1, and type 2 diabetic donors. To assess the presence of viral reads, we analyzed all reads not mapping to the human genome with the taxonomic classification system Kraken2 and its full viral database, augmented to encompass representatives for all (28) enterovirus B serotypes for which a complete genome is available. As a secondary approach, we input the same sequence reads into the STAR aligner using these 28 enterovirus B genomes as the reference. No enterovirus B sequences were detected by either approach in any of the 243 bulk RNA libraries nor in any of the 79 single cell RNA libraries. While we cannot rule out the possibility of a very low-grade persistent enterovirus B infection in the donors analyzed, our data do not support the notion of chronic viral infection by these viruses as a major driver of type 1 diabetes.

Keywords: type 1 diabetes, enterovirus B, persistent viral infection, RNA-Seq

Article Highlights

• Persistent enterovirus B infections of pancreatic islets have been suggested as trigger for autoimmunity leading to type 1 diabetes in genetically susceptible individuals.

• Unbiased sequence-based analysis of bulk and single cell RNA-Seq data from the Human Pancreas Analysis Program found no evidence for presence of enterovirus B sequences in the human pancreas.

• While our findings do not rule out the possibility of a very low-grade persistent enterovirus B infection, our data do not support the notion of chronic viral infection by these viruses.
The miR-203/ZBTB20/MAFA axis orchestrates pancreatic β-cell maturation and identity during weaning and diabetes
Authors: Li Yating , Yang Yuqian , Sun Yi , He Lu , Zhao Lin , Sun Haoran , Chang Xiaoai , Liang Rui , Wang Shusen , Han Xiao , Zhu Yunxia
Published: July 2024

ABSTRACT

Maturation of postnatal β cells is regulated in a cell-autonomous manner, and metabolically stressed β cells regress to an immature state, ensuring defective β-cell function and the onset of type 2 diabetes. The molecular mechanisms connecting the nutritional transition to β-cell maturation remain largely unknown. Here, we report a miR-203/ZBTB20/MAFA regulatory axis that mediates the β-cell maturation process. We show that miR-203 level in β cells changes during the nutritional transition and that miR-203 inhibits β-cell maturation at the neonatal stage and under high-fat diet (HFD) conditions. Using single-cell RNA sequencing, we demonstrated that miR-203 elevation promoted the transition of immature β cells into CgBHi endocrine cells, while suppressing gene expressions associated with β-cell maturation in a ZBTB20/MAFA-dependent manner. ZBTB20 is an authentic target of miR-203 and transcriptionally upregulates MAFA expression. Manipulating the miR-203/ZBTB20/MAFA axis may therefore offer a novel strategy for boosting functional β-cell numbers to alleviate diabetes.

Highlights

 Nutritional transition from high-fat-rich diet to carbohydrate-rich diet inhibits miR-203 expression.

 Failure to inhibition of miR-203 during HFD feeding causes β-cell immaturity and loss of identity.

 Ablation of miR-203 in β cells prevents HFD-induced β-cell dysfunction.

 The miR-203-ZBTB20-MAFA axis mediates β-cell immaturity and is conserved in humans.
Cryopreservation of stem cell-derived beta-like cells enriches for insulin-producing cells with improved function
Authors: M. Barra Jessie , T. Kratz Austin , Castro-Gutierrez Roberto , Proia James , Bhardwaj Gurprit , Phelps Ed , A. Russ Holger
Published: July 2024

Abstract:

The generation of stem cell-derived beta-like cells (sBC) holds extreme promise as not only an abundant insulin-producing cell source for replacement therapy of Type 1 diabetes (T1D), but also as an invaluable model system for investigating human beta cell development, immunogenicity, and function. Several groups have developed methodology to direct differentiate human pluripotent stem cells into pancreatic cell populations that include glucose responsive sBC. Nevertheless, the process of generating sBC poses significant experimental challenges. It involves lengthy differentiation periods, experiences substantial variability in efficiency, and inconsistencies in obtaining functional sBC. Here, we described a simple and effective cryopreservation approach for sBC cultures that yields homogeneous sBC clusters that are enriched for insulin expressing cells while simultaneous depleting proliferative progenitors. Thawed sBC display enhanced glucose-stimulated insulin release compared to controls in vitro and can effectively engraft and function in vivo. Collectively, this approach alleviates current challenges with inefficient and variable sBC generation while improving their functional state. We anticipate that these findings can inform ongoing clinical application of sBC for the treatment of patients with T1D and serve as an important resource for the wider diabetes field that will allow for accelerated research discoveries.

Article Highlights:

· Human stem cell-derived beta-like cells (sBC) are a vital tool for the field of diabetes research but are technically difficult to produce and challenging to maintain in culture.

· This manuscript describes a new cost effective and simple approach to cryopreserve differentiated sBC.

· Frozen and thawed (F/T) sBC are more uniform, display enriched beta cell fraction and improved function while depleting SOX9+ progenitors.

· F/T sBC can successfully engraft and display stimulated insulin release in the absence of any cystic structures.

· Cryopreservation will enable more researchers to utilize sBC for complex experiments to investigate human diabetes pathogenesis.
Redescription of Pseudobenedenia lauriei Szidat 1965 (Monogenea: Capsalidae) from Notothenia neglecta in Laurie, Peterman, and South Orkney Islands, South Antarctica
Authors: Rubtsova Nataliya Y , Marcotegui Paula
Published: July 2024

While reviewing museum collections of Pseudobenedenia Johnston, 1931, we found five deposited slides marked by Dr. Lothar Carlos Guillermo Szidat as Pseudobenedenia lauriei Szidat, 1965 from Notothenia neglecta Nybelin, 1951. We have removed the synonymization of Pseudobenedenia lauriei Szidat, 1965 as a junior synonym of Pseudobenedenia nototheniae Johnston, 1931 and restored its identity as a valid species that we redescribe herein. We added never-published data on the ovary, testes, bursa, haptor diameter, and egg of P. lauriei. As well, we added data on body size, measurements of sclerotized structures of haptor (accessory sclerites, anterior and posterior hamuli), oral suckers, pharynx and anterior hamulus to accessory sclerite ratio. A comparison of the measurements the presently recognized species of P. lauriei shows that it differs from all known species of Pseudobenedenia Johnston, 1931 and corresponds to the data of its original description. We provide photomicrographs of P. lauriei for the first time in addition to more informative line drawings of this species.
Asymmetry of Eye Peduncle Length in Euprotomus Iredalei (Abbott, 1960) (Mollusca: Neostromboidae: Strombidae)
Authors: Maxwell Stephen J , JL Watt , MA Payne
Published: July 2024

This study examines the difference in right and left ommatophore length of Euprotomus iredalei from Karratha, Western Australia. In all specimens examined (n = 39, Males = 21, Females = 18) there was no evidence of imposex in terms of sexual organ abnormality or gonadal form, and all animals had right and left ommatophores that were of different lengths. This length difference was significant (t(38) = 10.315, p < 0.001) in the length of the ommatophore with the right longer (8.86 mm ± 0.23 SE) than the left (7.32 mm ± 0.19), and the effect size was large (d = 1.05). There was no sexual dimorphism in the difference in proportional length of the ommatophore between males and females (t(38) = 0.056, p = 0.955). This paper indicated that the difference between the left and right ommatophore in the target species and not a consequence of imposex.
O USO DE VAGA ZERO NO SISTEMA ÚNICO DE SAÚDE E SEUS QUESTIONAMENTOS JUDICIAIS
Authors: Toledo Roberta Cristina Paganini , Betoni Hugo Vechiato , Leite Sara Ribas Ortigosa
Published: July 2024

O presente artigo pretende analisar a (in)constitucionalidade do uso da “vaga zero” no Sistema Único de Saúde, a partir da coleta dos argumentos favoráveis e contrários à constitucionalidade na jurisprudência do Tribunal de Justiça do Estado de São Paulo e da verificação da tendência de posicionamento desse tribunal. Os resultados mostram que, embora os objetivos dessa medida sejam legítimos – assegurar o atendimento em casos de urgência –, sua aplicação é bastante controversa, sobretudo diante do risco que oferece ao paciente e à unidade de saúde que o recebe. Por outro lado, os defensores da “vaga zero” sustentam que a intervenção do Judiciário nessa matéria ofenderia a Separação de Poderes. Diante desse impasse, observou-se que a questão está longe de ser pacificada na jurisprudência paulista, que persiste oscilando entre entendimentos opostos, ora dando preponderância a argumentos favoráveis à constitucionalidade, ora a argumentos desfavoráveis. Urge, portanto, a uniformização do entendimento jurisprudencial, para que se assegure o tratamento isonômico dos pacientes.
Long Term Effect of Residue Management, Nitrification and Urease Inhibitor on Non-target Soil Bacterial Community in Rice–Wheat and Maize–Wheat Cropping Systems
Authors: Chakraborty Ranabir , Purakayastha T. J. , Ramakrishnan B. , Kour Babanpreet , Bhowmik Arpan , Das Abinash
Published: July 2024

An investigation was carried out from November, 2020 to April, 2021 at the Indian Agricultural Research Institute, New Delhi, employing a split-split plot layout with two cropping systems (rice-wheat and maize-wheat), four long-term crop residue management strategies including burning (CRB), removal (CRR), incorporation (CRI), and biochar (BC), and two nitrogen management: neem-coated urea (NCU) and Urea+dual (urease+nitrification) inhibitor (UUINI). Soil DNA was extracted and quantified for 16S bacteria, 16S archaea, nifH, ureC and anammox abundances using quantitative PCR. Additionally, Soil samples were analysed for available nitrogen (urea, NH4+, NO3-) and water-soluble carbon. Rice-wheat rotations favoured higher 16S bacterial abundance while maize-wheat elevated 16S archaea. Notably, CRI and BC exhibited higher bacterial abundance compared to CRR and CRB, while minimal impact was noticed for archaea. The nifH gene abundance was influenced by all treatments along with their interactions. UreC gene copies exhibited a direct relationship with 16S archaea and an inverse relationship with 16S bacteria; UUINI showed a higher abundance of ureC under CRI and BC in both cropping systems. Moreover, anammox abundance correlated positively with NH4+ and NO3- but negatively with unhydrolyzed urea, indicating the inhibitory effect of UUINI. These findings underscore the complex relationships among inhibitors, residue management, cropping systems and soil microbial communities, emphasizing the need for tailored approaches to optimise nutrient cycling and soil health in agricultural systems.
Perencanaan Ruang Usaha PKL di Kompleks Terminal Dhaksinarga Wonosari Berbasis Komunitas
Authors: Damanik Imelda Irmawati , Raniasta Yohanes Satyayoga , Kinanthi Maria
Published: July 2024

The economic growth of the city is closely related to informal activities, one of which is street vendors (PKL - "Pedagang Kaki Lima"). PKL activities generally seek strategic urban spaces to conduct informal trading businesses. The Pedagang Kaki Lima community in Gunung Kidul has been given the opportunity to develop their trading activities in the Dhaksinarga terminal complex in Wonosari city. The existing condition of the Dhaksinarga terminal prompted the PKL vendors to contact the Urban and Settlement Environment Laboratory of the Faculty of Architecture and Design at UKDW to assist in planning the PKL business spaces with a people-oriented concept. In this community engagement (PkM) activity, the design process is carried out using a community-based design approach, with the aim of producing a design that suits the space needed for the unique trading activities of PKL vendors in Gunung Kidul, who are part of the PPKL-Gunung Kidul association. Moreover, considering that this business space is located within the Dhaksinarga terminal complex managed by the Department of Transportation, all design efforts must align with the public service function of the Dhaksinarga Terminal. This PkM process will be a collaboration between the community (PPKL-Gunung Kidul), academia (Urban and Settlement Environment Laboratory, UKDW), and the government (Department of Transportation), requiring mapping to ensure that all parties benefit from the PKL business space design activity.
Sistim Informasi Geografis Sebaran Objek Wisata Bahari di Kecamatan Salahutu, Pulau Ambon Berbasis Web Dengan Menggunakan ArcGIS StoryMaps
Authors: Rakuasa Heinrich , Somae Glendy , Sihasale Daniel Anthoni , Pakniany Yamres , Septory Juan Steiven Imanuel , Latue Philia Christi
Published: July 2024

Penelitian ini memperkenalkan penggunaan Sistem Informasi Geografis (SIG) dalam merancang platform web berbasis ArcGIS StoryMaps untuk memvisualisasikan dan mempromosikan objek wisata bahari di Kecamatan Salahutu, Pulau Ambon. Platform ini mengintegrasikan data geografis dengan elemen multimedia seperti gambar, video, dan teks naratif untuk menghasilkan pengalaman interaktif yang memadukan informasi tentang objek wisata, jalur perjalanan, serta budaya lokal. Melalui peta interaktif, pengunjung dapat menjelajahi lokasi objek wisata, mendapatkan informasi detail, dan memahami konteks lingkungan sekitarnya. Diharapkan platform ini akan memungkinkan promosi yang efektif terhadap keindahan dan daya tarik objek wisata bahari di Kecamatan Salahutu kepada berbagai jenis audiens, serta mendorong kesadaran akan pentingnya pelestarian lingkungan bahari.
UPAYA PENINGKATAN PEREKONOMIAN MELALUI EKSPOR PRODUK (MUKENA) DI BANGIL, PASURUAN. JAWA TIMUR
Authors: Rochdianingrum Widhi Ariestianti , Retnani Endang Dwi , Fidiana Fidiana , Widyawati Dini , Mustika Hindah
Published: July 2024

Kegiatan pengabdian ini dilakukan dengan tujuan utama untuk meningkatkan keberlangsungan perekonomian baik untuk pelaku UMKM mukena dan lingkungan sekitarnya, alasan kegiatan ini pada mukena dikarenakan mukena sebagai salah atau pakaian yang dipergunakan oleh umat islam khususnya kaum wanita, mukena memiliki model yaitu putusan dan terusan, memiliki varian warna dan motif. Pelaku UMKM mengalami suatu kendala karena adanya jumlah pembeli yang menurun selain karena adanya dampak Covid-19 juga karena adanya harga bahan yang meningkat. Adanya pengabdian ini untuk membantu menyelesaikan beberapa kendala yang ada, salah satu upaya yang dilakukan dalam hal ini berupa memperluas pangsa pasar ke negara lain (Asia), hal ini dilakukan karena kualitas produk (mukena) yang dihasilkan sangat baik dan layak direkomendasikan ke pihak asing. Bahan yang dipergunakan di bilang memiliki kualitas sangat baik karena bahan yang dipakai berasal dari bahan yang sudah sesuai dengan kondisi dan sesuai dengan selera pada umumnya konsumen dan pelanggan yaitu berbahan ringan dan nyaman tidak terasa panas. Ekspor merupakan suatu kegiatan yang bertujuan untuk meningkatkan pertumbuhan di segala sektor, salah satunya sektor berupa sektor ekonomi.
Forschende Fachdidaktik IV
Authors: Unger-Ullmann Daniela , Hofer Christian
Published: July 2024

In diesem Band greifen Forschende, die zum Teil selbst langjährig in der universitären Sprachenlehre tätig sind, relevante Forschungsthemen aus dem Sprachunterricht auf und bearbeiten diese im Rahmen fachdidaktischer Forschungsprojekte. Die beschriebenen Projektergebnisse werden nachhaltig in die Sprachenlehre integriert, um Qualitätsentwicklung zu gewährleisten, Kompetenzerweiterung der Lehrenden zu fördern und aktuelle bildungswissenschaftliche Themen, die aus gesellschaftlichen Transformationsprozessen resultieren, in den praxisrelevanten Kontext zu übertragen. Diesem ganzheitlich integrativen Forschungspostulat folgen vorliegende fachdidaktische Forschungsergebnisse nicht nur, sondern verdeutlichen darüber hinaus Konsequenzen für die fachdidaktische Bildungskultur, die sich etwa aus der Corona-Krise oder aus veränderten Zielgruppen universitärer Sprachkurse ergeben haben.
Tourismuspolitik
Authors: Bochert Ralf , Vogler Ralf
Published: July 2024

Ideal für Praxis und Wissenschaft

Urlaub ist die schönste Nebensache der Welt. Allerdings geht das Reisen mit Markt- und Staatsversagen einher. National und supranational müssen Regierungen deswegen den Tourismus politisch gestalten. Ralf Bochert und Ralf Vogler beleuchten die Tourismuspolitik im Detail: Zu Beginn skizzieren sie die Grundlagen von Tourismus und Politik. Zudem gehen sie u.a. auf Marktformen und Wettbewerb ein. Die Problematiken, die sich aus öffentlichen Gütern und Externalitäten ergeben, lassen sie nicht außer Acht. Privatisierung und Deregulierung thematisieren sie ebenso wie Lobbyismus und die Interessen der Stakeholder. Auf Basis dessen zeigen sie Handlungsfelder der Tourismuspolitik auf.

Das Buch richtet sich an Studierende, Praktiker:innen und Wissenschaftler:innen der Politik- und Tourismuswissenschaften.
The Anthropological Dimension of the Philosophy of Cosmocentrism of Antiquity
Authors: Мirgorodskiy Andrey A. ,   Donetsk branch of the Volgograd Academy of the Ministry of Internal Affairs  of the Russian Federation
Published: July 2024

The paper examines the content of the problem of man in ancient philosophy, in which anthropocentrism can be discerned long before the Renaissance. The problem of man forms an important part of reflections at all stages of cultural and historical development. In the philosophy of Antiquity, man and the Cosmos were never radically opposed. On the contrary, they always correlated with each other, because the Cosmos was under-stood as animate and human-like. At the same time, whatever the greatness of man, he always fit into the hori-zon of the cosmocentric worldview and did not surpass the Cosmos. The focus of Antiquity was the natural-cosmic life, in which he appeared exclusively as a natural being. In order to realize his potencies on the basis of love and creativity, from a means of achieving any natural-cosmic goals, man had to become a comprehen-sive and harmonious personality, first of all, in social life.
Philosophy as the Basis of Cultural Cognition
Authors: Khvoshchevskaya Irina V. ,   Yaroslav the Wise Novgorod State University
Published: July 2024

The relationship between philosophy and culture serves as a focal point in understanding the intricate dynam-ics of human civilization. This article delves into the historical evolution of the philosophy of culture as an inde-pendent scholarly discipline, tracing its origins from the turn of the XIX to the XX centuries. It examines various philosophical doctrines that have profoundly influenced the analysis of culture, including existentialism, sym-bolic forms, sociology of culture, and the philosophy of life. Cultural studies, inherently multidisciplinary, inter-sects with disciplines such as philosophy, sociology, political science, and psychology. Unlike cultural studies, which often focuses on empirical knowledge and representations of culture, the philosophy of culture seeks metaphysical insights into cultural phenomena. This article elucidates the methodological principles of cultural studies grounded in philosophical doctrines, exploring concepts like semiotics and hermeneutics for interpret-ing cultural texts and phenomena. The diversity within the philosophical theory of culture is underscored, high-lighting approaches such as the anthropological perspective, Marxism, and the information-semiotic approach. Each of these perspectives offers unique insights into the nature of culture and its dynamic interplay with socie-ty and the individual. In conclusion, the philosophical exploration of culture not only enriches our understanding of societal dynamics but also provides deeper insights into the existential and metaphysical dimensions of hu-man existence. By bridging empirical observations with philosophical contemplation, this interdisciplinary ap-proach fosters a comprehensive framework for comprehending the complexities of cultural phenomena.
Training and Development of Multitasking Specialists in a Modern Organization
Authors: Berezhnaya Maria S. ,   Financial University under the Government of the Russian Federation,   Institute of Educational Development Strategy
Published: July 2024

This article addresses the issue of training and developing multitasking specialists in modern organizations. In the face of talent shortages and high demand for multitasking employees, employers are faced with the need to effectively manage the process of employee training and development. The article describes current trends in employee education, including the use of modern HR tools, the creation of personalized development pro-grams, and the formation of talent pools. The author emphasizes the need for specialists to develop a wide range of skills, encompassing communicative, leadership, and digital competencies, along with the ability to adapt quickly and effectively plan work tasks. The author examines common pitfalls in career growth strategy development. The concluding part of the article emphasizes the importance of flexibility in employee training in 2024, describes organizations’ transition to digital learning platforms, and the integration of learning into the work process.
Modern Political Myths and Pseudo-Myths in the Aspect of the Theory of Ethnogenesis
Authors: Kravchenko Victoria V. ,   University of World Civilizations named after V.V. Zhirinovsky
Published: July 2024

The aim of this research is to apply L.N. Gumilev’s theory of ethnogenesis and A.F. Losev’s philosophical doc-trine on myth to modern political culture. The essential aspects of the political myth as an invariant of the ethnic myths are analyzed in the article; the ethnic myth itself is intepreted as an integral component of the ethnic mentality and spiritual life of the ethnos. The results of the study show that in modern political reality there are a number of myths and “pseudo-myths” that play a significant role in world politics. The varieties of these political myths are examined, which represent specific transformations of traditional myths. Artificial “pseudo-myths” are revealed as a result of political technologies and socio-political construction, which are essential in modern political reality. Particular emphasis is placed on the role of “pseudo-myths” created for political quasi-ethnicities forming in today’s globalized and individualized society, where traditional ethnic ties are breaking down or weakening. The further political development of individual ethnicities, nations, and humanity as a whole will depend on which myths define their current activities and prospective survival programs.
Multidisciplinary View on the Link of Environmental Activism with Art Creation - a Case Study of Recycled (Junk) Art
Authors: Kikuchi Ryunosuke ,   Centro de Estudos de Recursos Naturais, Ambiente e Sociedade, Instituto Politécnico de Coimbra, Portugal Faculty of Advanced Science and Technology, Ryukoku University, Japan
Published: July 2024

It is reported that the world of art needs more social enterprise and the world of social enterprise needs more art. Therefore, a case study of recycled art was carried out in order to investigate how the link between the art movement and the environmental movement has been formed. Recycled art is often considered as a form of environmental activism. However, there is a time lag of about half a century between the initiation of recycled art in the early 20th century and that of environmental activism (e.g. 3R's - reduce, reuse and recycle) in the 1970s. Recycled art is not historically linked with environmental activism, but it is currently and practically linked with environmental activism. The reuse/recycling of waste as an art tool was new and novel for the then progressive artists from the artistic viewpoint. Since there is now increasing concern over environmental issues and measures to address such issues across the world, the reuse/recycling of waste as an art tool is environmentally friendly from the 3R's viewpoint. That is, these two viewpoints are quite different, but the outcome of recycled art fulfills both interests – artistic creativity and waste abatement. Our modern society has a lot of complex problems; therefore, cooperation across different sectors is often required. Recycled art seems to be a thought-provoking example for working together across sectoral boundaries.
Legal Protection for Muslim Consumers Regarding Halal Food Certification in Law Number 33 of 2014 (Gazetted)
Authors: Kurnia Pradana Aditya Fajri , Muhammad Yunan Hidayat  , Sugiyat Sugiyat , Nafi' Hasbi M. Zidny
Published: July 2024

Purpose : “The purpose of this study is to analyse the legal protection for Muslim consumers of halal certified products in Law Number 33 of 2014.
Method : This research uses a normative juridical approach, namely research that is focused on legal norms relating to legal protection for Muslim consumers against halal food certification in Law Number 33 of 2014.
Result : The existence of various laws and regulations relating to halal labelling on food shows that the regulation is still partial. However, the existence of Law of the Republic of Indonesia Number 33 of 2014 concerning Halal Product Guarantee provides more legal certainty. Business actors who are required to include halal labels on food are one of the moral responsibilities of business actors.
Implication :The JPH Law provides several forms of legal protection for Muslim consumers. However, the implementation of the JPH Law still faces several obstacles. To improve legal protection for Muslim consumers, several efforts need to be made, such as increasing socialisation of the JPH Law, strengthening BPJPH, and improving coordination between institutions.
QCA-based design of polar encoder circuit
Authors: Vittapu Sravan Kumar , Sankuru Ravichand , Rakshana Chepuri , Mahesh Beeradhar , Teja Amudha Naga
Published: July 2024

In the last few decades, nano-electronic devices have been manufactured using VLSI technology. Over the past four decades, IC technology has been growing by using CMOS technology successfully, but this CMOS technology has a scaling limitation. To overcome this scaling limitation, QCA (quantum dot cellular automata) emerges as an alternative. This work is the implementation of the design of a polar encoder using QCA technology. This design is a single-layered and even bottom-up approach technique. The Polar code is more efficient and has less energy dissipation compared to the turbo code and conventional codes (CC). This design explores (8:4). A Polar encoder is designed to have fewer cells and area compared to the turbo encoder and conventional encoder. The proposed design is implemented using the QCA designer tool.
Personal data protection in fintech: A case study from Indonesia
Authors: Rohendi Acep , Kharisma Dona Budi
Published: July 2024

Personal data privacy regulation and mitigation are critical in implementing financial technology (fintech). Problems with fintech users’ data might result from data breaches, improper usage, and trade. Issues with personal data will result in financial losses, crimes, and violations of personal information. This legal research used three approaches: conceptual, comparative, and statute-based. In order to implement the statutory method, all laws and regulations pertaining to the legal concerns of information technology, fintech, personal data security, and protection are reviewed. Due to the nature of the sources of data, this study mainly used literature study and document observation to collect the data. Then, legal interpretation, legal reasoning, and legal argumentation are all included in the qualitative juridical analysis. This article recommends two strategies that Indonesia should take to provide personal data protection, including: 1) establishing the Personal Data Protection Commission (PDPC); and 2) improving the financial literacy of consumers.
Prognostic evaluation of glycogen synthase kinase 3A (GSK3A) mRNA expression in colon cancer patients
Authors: Walter Neha Sylvia , Kaur Jasmeet
Published: July 2024

Introduction: GSK3, a multifunctional serine/threonine kinase regulates cell-cycle progression, differentiation and apoptosis and its inhibition can have a tumor suppressor/promoter effect, depending on the cell type. There are conflicting reports of GSK3 in cell growth, but most studies have focused on GSK3β and very few on GSK3α in cancer. GSK3α regulates proliferation of melanoma and pancreatic and colon cancer cells, but the predictive role of GSK3A is not known in colon cancer. Material and methods: The prognostic role of GSK3A was assessed in colon cancer patients employing Kaplan-Meier plotter (KM plotter) database. Online ROC plotter tool was used to compare the GSK3A gene expression in colorectal cancer patients receiving any form of chemotherapy. Results: Current results show that higher GSK3A mRNA expression is significantly related to poorer Relapse Free Survival (RFS) in colon cancer patients. Assessment of GSK3A mRNA for different clinicopathological features like clinical stages, TP53 mutation, stage T and stage N highlighted the critical prognostic value of GSK3A mRNA in colon cancer. Discussion and conclusion: GSK3A will help to better predict colon cancer prognosis and to develop better treatment strategies for colon cancer patients and will be beneficial in combating the heterogeneity and complexity of colon cancer.
Exploring the application and value of martial arts in modern society by combining double difference models
Authors: Liu Minglong , Deng Haijuan
Published: July 2024

Properly acknowledging the application and value of modern Chinese wushu is essential for its ongoing survival and development and plays a pivotal role in shaping its future direction. This analysis delves into the application value of wushu within contemporary society, leveraging its unique characteristics and advantages. Specifically, the exploration is structured around four principal domains: competitive sport, tourism, technical labor, and martial arts training. These dimensions collectively underscore the multifaceted impact and significance of wushu in the modern era. Then, based on relevant theories, research hypotheses, and research variables are determined, a double difference model oriented to the socio-economic value of wushu is constructed, and the value of wushu is analyzed with the support of the model by combining relevant research data. The conclusion presents that the panel data of FDI, Service, and Urban are smooth at a 1% level, while the panel data of GDP and Events are smooth at a 5% level. The p-values of model (1) and model (2) are 0.206 and 0.388, respectively, which indicates that martial arts have a certain promotion effect on the development of the local economy.
Responsabilidad del fabricante por sus productos, contrato de seguro y acción directa: panorámica breve de la práctica española de Derecho internacional privado
Authors: Maseda Rodríguez Javier
Published: July 2024

En el ámbito de la responsabilidad por productos, este trabajo tiene por objeto la identificación de los problemas de Derecho internacional privado que se plantean en la práctica española relativa a las reclamaciones por los daños provocados por el empleo en distintas intervenciones quirúrgicas de naturaleza oftalmológica de un producto sanitario de la marca Ala Octa, fabricado por la empresa Alamedics GmbH AG y que resultó tóxico. Por un lado, y en tanto que las víctimas accionaron directamente contra Allianz Versicherungs AG en su calidad de compañía de seguros de Alamedics GmbH AG, los problemas relativos al régimen de la acción directa, dependiente de la ley rectora de un contrato de seguro regulado por el Reglamento Roma I y de la ley rectora del daño, cuya determinación corresponde al Reglamento Roma II. Por otro, los problemas derivados del juego (imperfecto) de las normas de conflicto, especial y general, del Reglamento Roma II. Y, finalmente, el desconocimiento de las cláusulas de compatibilidad que regulan la convivencia del Reglamento Roma II con el (ignorado) Convenio de La Haya de 1973 sobre ley aplicable a la responsabilidad por productos.
International summer schools as a platform of inclusive education for doctoral students
Authors: Bagchi Suparna
Published: July 2024

This paper is based on reflections on my understanding of international summer schools, drawing from my personal experiences while participating in one of them, which took place in a European country in 2021. I argue that international summer schools can play an important role as an international academic forum in the practice of inclusive education for doctoral students and early career researchers from various perspectives. I use the model of three levels of inclusion advanced by Qvortrup and Qvortrup to justify my arguments in this autoethnographic study. I discuss the study methodology and provide an overview of the timetable followed by the international summer school that I attended. Then, I argue how it provided an inclusive learning experience to the participant students from numeric/physical, social, and psychological perspectives. I conclude by observing that international summer schools need to utilise their transnational nature to initiate race-sensitive, culturally responsive discussions among their participant students. This approach will help to create critical cultural awareness among its students, trying to give a clear picture of the intercultural makeup of the world as it exists.
Weight loss, diarrhea, and polyneuropathy: could it be amyloidosis?
Authors: Galindo Luis Francisco Pineda , Cortés Zully Esmeralda Contreras , Martínez Andrea Avila , del Rosario Mora Campos María , Jiménez Elsa Acosta , Torres Armando Pérez
Published: July 2024

Background:

Amyloidosis is a multisystemic disease that may be hereditary, characterized by the deposit of amyloid in the extracellular space. Transthyretin-mediated (ATTRm) amyloidosis is the most common subtype of heredofamilial amyloidosis. The diagnosis is based on clinical suspicion and amyloid in tissues. Hepatic transplantation is the only treatment that prevents the synthesis of the amyloidogenic variants of transthyretin protein.

Case Presentation:

A 34-year-old male presented with weight loss, gastrointestinal symptomatology, and polyneuropathy associated with histopathologic deposits of amyloid in gastrointestinal and fat tissue as well as peripheral nerve.

Conclusion:

Hereditary familial amyloidosis (HFA) is a relatively rare disorder that leads to erroneous and delayed definitive diagnosis. Therefore, the diagnosis should be first based on a suspicion of the disease, and then proceed according to complete protocol.
Artificial Intelligence-Driven Video Indexing for Rapid Surveillance Footage Summarization and Review
Authors: Jung Jaemin , Park Soonyong , Kim Harim , Lee Changha , Hong Charmgil
Published: July 2024

This paper introduces VIDEX, an advanced tool designed to streamline the analysis of surveillance video through a user-friendly interface. VIDEX achieves high development efficiency and maintainability utilizing the Model-View-ViewModel (MVVM) design pattern. The core feature of VIDEX is a footage summary using object detection and anomaly detection. Its architecture ensures efficient data management by organizing detected objects and anomalies within an indexed database, thus facilitating a more rapid review process. Additionally, multi-threading was used to shorten the processing time. VIDEX provides a video summarization that can be used primarily in the criminal investigation stage using the information stored in a database. Discover more about VIDEX and access its resources at https://github.com/nth221/videx.
iFakeDetector: Real Time Integrated Web-based Deepfake Detection System
Authors: Lee Kangjun , Jung Inho , Woo Simon S.
Published: July 2024

Recently, deepfake detection research has been actively conducted. While many deepfake detectors have been proposed, validating the practicality of such systems against real world settings has not been explored much. Indeed, there are some gaps and disparities when they are applied in the real world. In this work, we developed a real time integrated web-based deepfake detection system, iFakeDetector, which incorporates the recent high performing deepfake detectors, and enables easy access for non-expert users to evaluate deepfake videos. Our system takes a deepfake video as input, allowing users to upload videos and select different detectors, and provides detection results on whether the uploaded video is a deepfake or not. Also, we provide an analysis tool that enables the video to be analyzed on a frame-by-frame basis with the probability of each frame being manipulated. Finally, we tested and deployed iFakeDetector in a real world scenario to verify its practicality and feasibility.
CLR-Face: Conditional Latent Refinement for Blind Face Restoration Using Score-Based Diffusion Models
Authors: Suin Maitreya , Chellappa Rama
Published: July 2024

Recent generative methods have shown promising blind face restoration performance. They usually project the degraded images to the latent space and then decode high-quality faces either by single-stage latent optimization or directly from the encoding. Generating fine-grained facial details faithful to inputs remains challenging. Most existing methods produce either overly smooth outputs or alter the identity. This could be attributed to the typical trade-off between quality and resolution in the latent space. If the latent is highly compressed, the decoded output is more robust to degradations but shows worse fidelity. On the other hand, a more flexible latent space can capture intricate details better, but is extremely difficult to optimize for highly degraded faces. We introduce a diffusion-based-prior inside a VQGAN architecture that focuses on learning the distribution over uncorrupted latent embeddings. We iteratively recover the clean embedding conditioning on the degraded counterpart. Furthermore, to ensure the reverse diffusion trajectory does not deviate from the underlying identity, we train a separate Identity Recovery Network and use its output to constrain the reverse diffusion. Specifically, using a learnable latent mask, we add gradients from a face-recognition network to a subset of latent features that correlates with the finer identity-related details in the pixel space, leaving the other features untouched. Disentanglement between perception and fidelity in the latent space allows us to achieve the best of both worlds. We perform extensive evaluations on multiple real and synthetic datasets to validate our approach.
Expressiveness is Effectiveness: Self-supervised Fashion-aware CLIP for Video-to-Shop Retrieval
Authors: Tian Likai , Yang Zhengwei , Hu Zechao , Li Hao , Yin Yifang , Wang Zheng
Published: July 2024

The rise of online shopping and social media has spurred the Video-to-Shop Retrieval (VSR) task, which involves identifying fashion items (e.g., clothing) in videos and matching them with identical products provided by stores. In real-world scenarios, human movement in dynamic video scenes can cause substantial morphological alterations of fashion items with aspects of occlusion, shifting viewpoints (parallax), and partial visibility (truncation). This results in those high-quality frames being overwhelmed by a vast of redundant ones, which makes the retrieval less effectiveness. To this end, this paper introduces a framework, named Self-supervised Fashion-aware CLIP (SF-CLIP), for effective VSR. The SF-CLIP enables the discovery of salient frames with high fashion expressiveness via generating pseudo-labels from three key aspects of fashion expressiveness to assess occlusion, parallax, and truncation. With such pseudo-labels, the ability of CLIP is expanded to facilitate the discovery of salient frames. Furthermore, to encompass the comprehensive representations among salient frames, a dual-branch graph-based fusion module is proposed to extract and integrate inter-frame features. Extensive experiments demonstrate the superiority of SF-CLIP over the state-of-the-arts.
OSIC: A New One-Stage Image Captioner Coined
Authors: Wang Bo , Zhang Zhao , Zhao Mingbo , Jin Xiaojie , Xu Mingliang , Wang Meng
Published: July 2024

Mainstream image captioning models are usually two-stage captioners, i.e., encoding the region features by a pre-trained detector and then feeding them into a language model to generate the captions. However, such a two-stage procedure will lead to a task-based information gap that decreases the performance, because the region features in the detection task are suboptimal representations and cannot provide all the necessary information for subsequent captions generation. Besides, the region features are usually represented from the last layer of the detectors that lose the local details of images. In this paper, we propose a novel One-Stage Image Captioner (OSIC) with dynamic multi-sight learning, which directly transforms the images into descriptive sentences in one stage for eliminating the information gap. Specifically, to obtain rich features, multi-level features are captured by Swin Transformer, and then fed into a novel dynamic multi-sight embedding module to exploit both the global structure and local texture of input images. To enhance the global modeling capacity of the visual encoder, we propose a new dual-dimensional refining to non-locally model the features interaction. As a result, OSIC can directly obtain rich semantic information to improve the captioner. Extensive comparisons on the benchmark MS-COCO, Flickr8K and Flickr30K datasets verified the superior performance of our method.