bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPING OF INSTRUMENTS ON BASIC COMPETENCIES TO KNOW AND USE LETTERS, NUMBERS AND ETHICS WITH QUIZIZZ
Authors: Nugraha Agri Triya , Rohendi Dedi , Purnawan Purnawan
Published: November 2023

At the beginning of 2020, the emergency of the corona virus which caused an uproar in various countries in the world. Indonesia was one of the countries affected by the Covid-19 pandemic  virus. Corona virus disease 2019 (COVID-2019). This has an impact on the world of education, in the midst of the Covid-19 pandemic, the learning and assessment process must still be carried out. Remote assessment evaluation tools can use applications, there are many applications that can be selected by the teacher. One of them is the quizizz application, researchers chose the quizizz application because the quizizz feature can be fully felt for free, while other applications need to upgrade to the paid version to get more varied features and the quizizz apllication can be played in support of exam mode and can load many participants. The research aims at; (1) Producing basic competency instruments to recognizing and using letters, numbers and tags in technical drawings (2) Obtaining instrument eligibility data based on expert tests, and (3) Obtaining instrument validation data, including validity, reliability, differentation, and diffuclty index. The method used is the ADDIE model development method consisting of steps of analysis, design, develop, implement and evaluate. The research has produced a basic competency instrument of recognizing and using letters, numbers and etiquette in the subject of technical drawing of class X light vehicle engineering in the form of an objective test of multiple choice 5 options totaling 30 items. The average result of the validation of all expert tests was 81,5 % with the very valid category. The results of the instrumen testing on students showed that all items were valid, high realibility with difficulty index ;  27 % easy, 60 % moderate, 13 % difficult, and their distinguishing power ; 80 % is in the fair category and 20 % is in the good category.
OPTIMIZATION IN USING ONLINE LEARNING MEDIA DURING THE COVID-19 PANDEMIC AT SMKN 2 INDRAMAYU
Authors: Huwaidi Fahmi , Nandiyanto Asep Bayu Dani , Azis Ghani , Pratama Muhammad Fawwaz wahyu
Published: November 2023

WHO (World Health Organization) has designated Covid-19 as a global pandemic, because it has the opportunity to infect populations worldwide. Therefore, in an effort to break the chain of the spread of Covid-19, the Minister of Education and Culture issued a learning regulation during the pandemic, namely the learning process carried out remotely from home through online learning. This makes the use of social media or video conferencing an urgent matter to replace the usual face-to-face learning system. Effectiveness and student understanding are the main focus in this research to create effective, innovative, and creative online learning.
THE USE OF LESSON PLAN GUIDELINES BASED ON LEARNING MODELS TO FACILITATE VOCATIONAL TEACHERS TO DEVELOP COMPETENCY INDICATORS
Authors: Suherman Amay , Komaro Mumu
Published: November 2023

The gaps in student competence with industrial demands make graduates of vocational high schools not widely absorbed in the workforce. This study aims to enhance the ability of vocational teachers in compiling indicators of competency using a lesson plan guidelines based on a learning models. The study was conducted with a qualitative approach through the action research method. The participants involved in this study came from three vocational schools in Bandung, West Java, Indonesia. The informants involved in this study were six male teachers, having more than five years of work experience and teaching productive subjects. Data collection by Focus Group Discussion (FGD) to obtain general information and individual interviews to obtain more specific data. After the data is documented and evaluated, then proceed with guiding respondents to develop indicators of competence using the lesson plan guidelines. The results of the research are expected to increase the ability of teachers to compile indicators of competence through the guidance of the lesson plan based on a learning models. So that this research will have implications for the achievement of student competencies in accordance with the demands of the job/industry.
THE INFLUENCE OF ONLINE LEARNING VIA WHATSAPP ON STUDENTS’ LEARNING MOTIVATION IN PMKR SUBJECT
Authors: Subagja Rizky Eka , Suherman Amay , Sukrawan Yusep
Published: November 2023

Online learning as a concept certainly has several variables, one of which is student learning motivation. This study aims to determine how much influence caused by online learning via WhatsApp on students' learning motivation and to find out whether online learning has a significant effect and has a positive or negative relationship on students' learning motivation. The author raised the topic of this study after conducting a survey to 15 students and seeing the facts in the form of learning outcomes which indicated a lack of student motivation in online learning. The design of this study used a mix method approach. Data collection techniques use a questionnaire, observation, interview and data analysis using simple linear regression analysis. The results showed that online learning via WhatsApp had a significant influence and had a positive relationship on students' learning motivation, as well as an influence of 55,7% on students' learning motivation, 60.6% on students' desire to carry out learning activities, 30.4% on students' interest in learning activities, 25.7% on encouragement of students to carry out learning activities, 15.2% of the needs of students to carry out learning activities, 8.2% of the students' expectations to achieve their goals, 17.6% of students' desire to achieve their goals, 28.8% of self respect, 18.7% to the attractiveness of learning activities, by 28.3% to the conduciveness of the learning environment.
OPTIMIZATION OF WORKSHOP FACILITIES IN VOCATIONAL SCHOOL TO SERVE THE PRACTICUM OF LIGHT VEHICLE ENGINE MAINTENANCE
Authors: SUJADI SUJADI , Faza Ibnu Nur , Sriyono Sriyono , Noor Ridwan Adam M
Published: November 2023

This research is motivated by the lack of optimal practical infrastructure in vocational schools on the subject of light vehicle engine maintenance. This study aims to optimize the practice facilities at SMK PU Negeri Bandung. The method used in this research is a quantitative descriptive method with instruments of observation, interviews and documentation, then the collected data is processed statistically. The results showed that the light vehicle technique had the smallest ratio between the area of the room and the number of students among other skill competencies. The level of availability of infrastructure for an engine work area of 96 m², an electrical work area of 48 m², a chassis work area of 64 m², an instructor's room work area of 48 m² and an overall workshop area of 256 m² so that if categorized as standard workshop infrastructure at SMK PU Negeri Bandung 25% less than the standard BSNP and Permendiknas RI No. 40 of 2008. Therefore, optimization is done by making a practice schedule to increase the arrangement and use of practical infrastructure to 80%.
Analisis Pembelajaran Penjas Pada Saat Pandemi Covid 19 Di Sdn Ciaro III
Authors: Rasyd Harun Al , Saptani Entan , Safari Indra
Published: November 2023

Pandemi Covid-19 menyebabkan berbagai permasalahan pada berbagai sektor kehidupan, tidak terkecuali dalam pelaksanaan pendidikan. Pelaksanaan pendidikan di Indonesia selama setahun kebelakang diselenggarakan secara daring, begitupun dengan pembelajaran penjas yang berbasis praktik. Berkaitan dengan pelaksanaan pembelajaran penjas secara daring tentunya kegiatan pembelajaran maupun segala bentuk persiapan guru dalam mengajar sangat berbeda dengan pelaksanaan pembelajaran penjas pada umumnya, yang akan meninggalkan persepsi baru bagi siswa. Maka dari itu pada penelitian ini, peneliti berupaya untuk menganalisis pembelajaran penjas pada masa pandemi Covid-19. Penelitian ini menggunakan teknik analisis data deskriptif kualitatif, dimana penelitian ini menggunakan metode survei dan teknik pengumpulan data kuisioner. Sampel penelitian adalah siswa SD kelas VI SDN Ciaro III. Dari penelitian ini dapat menunjukan bahwa pembelajaran pendidikan jasmani secara daaring di masa pandemi covid di SDN Ciaro III kurang baik.
Physical Activity Levels in High School Students in West Java during the Covid-19 Pandemic
Authors: Tarigan Beltasar , Hidayat Teten
Published: November 2023

The study aimed to obtain empirical evidence about the direct impact of the COVID-19 pandemic on the active lifestyle of high school students in West Java and the activities carried out during the Covid-19 pandemic. The study population included high school students in West Java, while the samples were chosen randomly, involving 1,715 students representing each district in West Java. The research method used was the descriptive quantitative method. The instrument used was a physical activity questionnaire for children (PAQ-C). Data analysis employed Microsoft Excel and SPSS 24. The results showed that the student's active life behavior before the Covid-19 pandemic was mostly distributed in the high (857 people, 50%) and moderate (824 people, 48%) categories. Meanwhile, during the Covid-19 pandemic, the most distribution was in a low category (847 people, 49%). The level of student active behavior before the covid-19 pandemic was in the high category, while the level of student active behavior during the covid-19 pandemic was in a low category. This data showed that the COVID-19 pandemic decreased the student's active living behavior from the moderate to the low category. Before the Covid-19 pandemic, the activities carried out were jogging, traditional sports, football, volleyball, badminton, basketball, futsal, Pencak Silat, strength training, and gymnastics. Meanwhile, the activities carried out during the pandemic included sunbathing, walking, jogging, cycling, watching more TV, playing games, sleeping, sitting around, and helping the elderly.
The Role and Mechanism of Cinnamon for Athlete Metabolism and Recovery Process: A Systematic Literature Review
Authors: Hasan Muhamad Fahmi , Adnyana I Ketut , Bahri Samsul , Ray Hamidie Ronald Daniel
Published: November 2023

Athletes have a high need to maintain their performance to stay fit while performing a high training intensity and frequent exercise. It makes athletes have a high need for supplements. However, athletes are prohibited from taking supplements included in the doping category. The lowest risk of doping is herbal-based supplements. This study used a systematic review method. The screening employed the PRISMA method as the preferred reporting item for systematic review and meta-analyses. The articles were obtained from Scopus and Dimensions databases using “cinnamon” as the keyword. Furthermore, the words "cinnamon" and "athlete" were added so that the data were obtained more specific. The exclusion criteria of this study involved original article documents, while the inclusion criteria included not more than 5-year publications. In the article selecting process, there were four articles that fulfilled the inclusion and exclusion criteria stating that cinnamon was effective for preventing inflammation that had an impact on accelerating recovery in athletes. Cinnamomum zylanicum is the most effective type of cinnamon for athlete recovery. It is because Cinnamomum zylanicum contains the most Cinnamaldehyde to help speed up recovery, which is most suitable for athletes. Thus, cinnamon is expected to be an alternative supplement for athletes to improve their performance.
Content Validity of Self-Talk Guidance as a Psychological Skill Training Tool for Athletes
Authors: Candra Adiska Rani Ditya , Sobihin S , Yudhistira Dewangga , Romadhoni Wiga Nurlatifa , Wicaksono Anggit , Anggita Gustiana Mega , Ali Mohammad Arif
Published: November 2023

Psychological factors that can potentially improve athlete performance are called Psychological Skills Training (PST). PST refers to psychological skill training that is systematic and consistent in improving the athlete’s performance and achievement. Studies on the effectiveness of psychological techniques, such as self-talk, imagery, and goal setting, are often used as training tools for athletes. This study aimed to determine the content validity of the Self-talk Guide Book developed as a guide for implementing psychological exercises for athletes. This Book contained the types of self-talk, how to apply it, and ways for athletes to easily respond to any negative self-talk arising in their minds. The research used Research and Development method with the ADDIE design which focused on the "Development" stage. The target of this research was experts, including psychologists and mental coaches, to examine the content validity of the book. The analysis used was Aiken Validity and Combat Alpha. The Aiken Validity formula test gained a score of 0.700 to 1.000. The result indicates that the resulting content validity is High. The results of this study can be used as a guide to carry out the next stage of the "Self-talk Guidance" development, namely the Implementation and Evaluation stages so that the resulting book has good quality and is suitable for guiding athletes in practicing self-talk.
Improving Adolescent Life Skills through Sport Programs at the Child Correctional Institution
Authors: Sobarna Akhmad , Hamidi Ahmad
Published: November 2023

This study was aimed to examine the integration of life skills in sport training programs. Participants of this study were adolescent aged 14 -19 years, involving 22 adolescents (11 adolescents receiving the Life Skill program, 11 adolescents receiving regular exercise training without life skill programs). Sampling technique used in this study was the intact group technique. The method used was experimental method with a quasi-experiment model and pre-test post-test control group design. The instrument of this study was an instrument from Cronin and Allen (2017) containing eight life skills taught in a sports training program. The results of this study indicate that the sport program containing life skills in a structured and deliberate manner had an influence on the life skills of adolescent at Correctional Institution in Bandung City. The highest increase of life skill component in the integrated life skill group was leadership with the average development of 1.25. Meanwhile, the life skill component that had the highest increase in the non-integrated life skill group was the emotional skill with the average development of 0.70. In conclusion, the provision of sport programs integrated with life skills in a structured and deliberate manner is proven to be able to develop life skills and could improve the life skill of adolescent higher than sports programs that are not structured and intentionally integrated with life skills.
Effects of Structured Games Led by Classroom Teachers on Preschool Student Fundamental Motor Skills
Authors: Friskawati Gita Febria
Published: November 2023

Early childhood is a golden period for growth and development, including Fundamental Movement Skills (FMS). However, motor learning through games is often neglected. This study was aimed to reveal the impact of playing games led directly by the class teacher on student FMS mastery. Ex post facto research was conducted on children aged 5-7 years who had received a structured game program intervention led directly by their class teacher. A total of 30 children participated in this study, consisting of 12 boys and 18 girls. This program had been incorporated into the early childhood education curriculum at the school where the research took place. FMS was measured using TGMD-2. An independent t-test was used to reveal differences of the results of FMS of the children. The results of the study showed that there were differences in the acquisition of FMS between boys and girls, where the boys gained a higher locomotor skills compared to the girls. In contrast, the mastery of manipulative skills was higher in the girl group. This study concludes that it is important to integrate structured game programs in the early childhood education environment.
Improving Range of Motion through Leg Extension Exercise and Static Bike Exercise for Osteoarthritis Genu
Authors: Paramurthi I.A. Pascha , Suparwati Komang Tri Adi , Prianthara I Made Dhita , Yuliana I Wayan Aris
Published: November 2023

Aging is identical with decreased functional abilities, such as prolonged standing, walking, squatting, running, or other activities. These decreases in functional ability can be caused by a degenerative disease, namely osteoarthritis (OA) genu resulting in a limited motion in the knee joint caused by a decrease in range of motion. Treatments for OA Genu cases include leg extension exercise and static bike exercise to maintain and to increase the range of motion (ROM) of knee joints.  This study was a Quasi Experimental study. The study lasted for five weeks from May-June. The sample of this study were 24 people. The results of the study found that the ability to movement extension and knee flexion in both groups increased. Both groups obtained p  value = 0.625 for extension and p value = 0.062 for flexion.  The p value of extension and flexion is p0.05. Results showed that, after the intervention in both groups, the osteoarthritis  patients at Siloam Hospitals Bali had improved flexion ROM and knee extension. Based on the difference value before and after treatment, the percentage increase in range of motion extension and flexion in the static bike group was slightly higher than the leg extension exercise group. It concludes that leg extension exercise and static bike exercise are equally good in increasing ROM of osteoarthritis patients. Leg extension exercises and static bike exercise can be used as alternative exercises to improve the ability to bend and to straighten knee joints experiencing limitations or stiffness.
Improving Fundamental Movement Skills in Early Childhood through Outdoor Play Based on Gender
Authors: Supriady Andy , Mahendra Agus , Budiana Dian , Ma’mun Amung
Published: November 2023

Basic movement skill (FMS) is an important factor that can influence physical activities. Playing outside can support a child overall health, learning process, and basic motor skill development. The purpose of this study was to determine early childhood motor development through outdoor play based on gender differences. This study used an experimental method with a one-group pretest-posttest design. The study population consisted of preschool children aged 5–6 years. The sample included 30 preschool children selected using purposive sampling, consisting of 12 boys and 18 girls. TGMD-2 test instrument was used to measure FMS. The results showed that there was no difference of the effect of the outdoor play program on the basic motor skills (FMS) of boys and girls. Locomotor skills and control objects indicates that there was a significant effect of the program intervention. It concludes that early motor skills of boys and girls were improved after participating in an outdoor play program. According to the result of this study, it is necessary to conduct a more detailed approach on gender differences, especially on their basic motor needs and participations in programmed outdoor activities to encourage the development of basic motor skills (FMS).
Improving Learning Outcomes in Short-Distance Running Through a Play-Based Approach for Grade V Students
Authors: Aji Bayu Purnomo , Wismanadi Himawan
Published: November 2023

Sprinting requires one aspect of fitness, namely speed, which serves to support the body's ability to perform the same and repeated movements in a short time. This study aims to determine the level of effectiveness in improving the learning outcomes of 30-meter short-distance running using a play-based approach. The method used is action research, conducted in two cycles. The subjects of this study were 35 fifth-grade students from SD Negeri Manukan Wetan IV Surabaya, consisting of 13 boys and 22 girls. The study utilized pre-test and post-test data collection techniques. Before the implementation of action research, the students had an average completion score of 36 for short-distance running. This score increased to 45.71 in cycle I. In cycle II, the initial student score of 58.29 improved to 90.29, with 4 students failing to complete the test. Therefore, it can be concluded that the play-based approach has proven effective in enhancing the learning outcomes of 30-meter short-distance running for fifth-grade students at SD Negeri Manukan Wetan IV Surabaya for the 2022/2023 school year.
Fertility Services & Training: What the Future Beholds
Authors:   Department of Obstetrics & Gynaecology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Kuala Lumpur, Malaysia., Abdul Karim. Abdul Kadir
Published: November 2023

The world of assisted reproductive technology is rapidly expanding worldwide with new improvements and constantly developed techniques. Two of the important factors affecting the success of any centre are the reproductive clinician and the embryologist. While training programme for reproductive clinician has been established, less so is said for embryologist. As the pioneer and leading fertility centre amongst universities in the country, Universiti Kebangsaan Malaysia Medical Centre (UKMMC) is making steps towards introducing a clinical embryology programme that is hoping to set a standard for embryologist training for the country and region. Fertility preservation is an area of assisted reproduction that is fast gaining recognition. It gives hope, especially to young oncologic patients for future reproduction. International success with ovarian tissue cryopreservation and reimplantation culminating with the first birth in 2004 gives hope to these patients. With the current plans of expansion and training of our reproductive centre, an oncofertility unit with ovarian cryopreservation facilities will be soon established to cater to the needs of the country.
MIGRATION OF POPULATION IN THE NORTHERN BORDER REGIONS OF AZERBAIJAN
Authors:   Institute of Geography named after academician H.A. Aliyev, Ministry of Science and Education of the Republic of Azerbaijan, Abdullayeva Gulnara
Published: November 2023

Purpose. The main purpose of the research work is to study the migration features of the population in the northern border regions of Azerbaijan, to identify existing problems in this area and to identify ways to solve them. Method. Comparative analysis, attractiveness of the area, statistical methods were used in writing the article. The northern border regions of the Republic of Azerbaijan were chosen as the research object. Conclusion. Despite the implementation of several state programs from 2004 until now, there is inequality in the socio-economic development of the regions of the Republic of Azerbaijan. Unlike the Baku-Absheron zone, there are still serious problems in the socio-economic life of the population in other regions. This leads to an increase in unemployment and poverty in the regions, migration of the population to Baku. Since the border regions are of strategic importance for the state, more attention should be paid to the employment of the population in order to keep them on the ground. Taking into account the strategic importance of the border position of the northern border regions of the Republic of Azerbaijan and the extreme natural conditions in the mountainous area, it is necessary to give certain concessions to the population living here for the sustainable socio-economic development of the border settlements. The creation of certain infrastructures should be carried out directly at the expense of the state, and for their continuous, constant activity, it is advisable to have these enterprises under state control. Scientific novelty. Demographic development and participation of the population in the migration process in the northern border regions of Azerbaijan were studied. As a result of these studies, it was found that in some settlements, as a result of the decline in natural growth and migration, the population has sharply decreased. The recommendations and suggestions given in the article are important for determining the strategic importance of population settlement in the northern border regions and eliminating existing problems in the field of demographic development.
GROUPING OF GEOSYSTEMS ACCORDING TO THE DEGREE OF ECOLOGICAL TENSION AND ORGANIZATION OF ECOLOGICAL MANAGEMENT IN LANDSCAPE PLANNING
Authors:   Institute of Geography, Ministry of Science and Education Republic of Azerbaijan, Baku, Azerbaijan, Ismayilov Mirnuh Javad oghlu , Gulıyev Mirmahmud Ramiz oghlu ,   Institute of Geography, Ministry of Science and Education Republic of Azerbaijan, Baku, Azerbaijan
Published: November 2023

Aim: This article aims to assess the ecological situation in the Gudyalchay-Samurchay interfluve area to support landscape planning and socio-economic management. The study focuses on identifying natural-anthropogenic effects, sustainability, natural resources, socio-economic functions, and natural-anthropogenic conflicts in the area. Methodology: The study employs landscape-ecological planning and analysis techniques to evaluate the ecological condition of landscapes in the area. The tension level of the ecological situation is categorized into five levels: satisfactory, dangerous, stressed, crisis, and catastrophic. The assessment considers various landscape types and their structural and functional characteristics, as well as the impact of natural and anthropogenic factors. Results: The study reveals that landscapes with satisfactory ecological conditions are predominantly found in nival and subnival rock-glacial ecosystems. However, other landscape types show limited areas with satisfactory conditions. Dangerous, stressed, crisis, and catastrophic ecological situations are observed in different landscape types, with varying degrees of ecological stress and irreversible changes in the landscape components. The ecological assessment and the implementation of the ecological carcass concept are crucial for landscape planning and the sustainable development of the Gudyalchay-Samurchay interfluve area. The findings provide valuable insights for policymakers and land managers in balancing socio-economic activities with ecological considerations, protecting natural resources, and improving the overall ecological situation in the region. Scientific Novelty: The article highlights the concept of the ecological carcass as a framework for nature protection and management. It emphasizes the importance of specially protected natural areas, ecological corridors, natural forest ecosystems, and ecological education for local communities. The ecological carcass approach aims to ensure the ecological balance, prevent biodiversity loss and landscape degradation, and promote sustainable coexistence of humans and natural resources.
THE PRINCIPLE OF BASIN MANAGEMENT OF WATER RESOURCES AS A WAY TO BALANCED DEVELOPMENT OF UKRAINE
Authors:   Institute of Geography NAS of Ukraine  Kiev, Ukraine, Kush Alexey
Published: November 2023

The purpose of the article is to carry out a detailed analysis of the provisions and rules of water resources management according to the basin principle. The main goal is to analyze the characteristics of water use according to a comprehensive European approach. It is important to reveal the essence of the basin principle in the article. Research methodology. The article is based on the results of the author's research and reasoning regarding the assessment of the influence of the basin principle of water resources management at the legal level. The article contains the author's analysis of the main tools of the basin principle of water resource use. The author considers European norms and rules for the use of water resources. In addition, the author evaluates the ecological concept of water resources management according to the basin principle and the consequences of its implementation in the water market of Ukraine. Also, the article is based on the basic documents of European and Ukrainian legislation in the field of management and protection of water resources. Research results. The main aspects and features of the implementation of the basin principle in the Ukrainian legislative field have been studied. The problems and advantages of the basin principle of water use are revealed. The positive side of the integrated approach in water resources management is revealed. The main mechanisms of the integral principle of the use of water resources are revealed in detail and their impact on river basins is analyzed. The possibility of solving water conflicts and the transition to a sustainable approach in the field of water use was assessed. The main terms and interpretation of the water legislation of the basin principle of resource management are considered. Modern problems in the field of water use and in the policy of water resources management have been identified. Scientific novelty. The theoretical aspects of the implementation of the European principle of water use and its impact on the water potential of Ukraine are considered. Found ways to resolve the water conflict between business entities. The article contains ideas for the development of a sustainable approach to water management. A modern, mature ecological concept at the legislative level in the direction of water use is proposed. Effective proposals for changing the system of water resources use to improve the ecological situation are provided. In the article, more attention is paid to sustainable balanced development of water use. The article reflects the main components of a sustainable policy in the European Union in the direction of protection, restoration and development of water potential, and reveals the necessary components that are needed to ensure a rational, balanced development of resources. In addition, the article contains the main provisions and documentation of European water legislation.
Investigating the Antimicrobial Efficiency of Staple Food Against Enteric Pathogens
Authors: Heyuan Xu  , Sayyida Aiza Bukhari  , Nawab Ali  , Muhammad Ilyas  , Muhammad Abubakar  , Muhammad Haidar Zaman
Published: November 2023

Background: The advent of antibiotics has significantly decreased human death rates. However, the problem of antibiotic overuse and the number of individuals who maintain a suspicious and defensive stance towards medicines remain unresolved concerns. Hence, it is important to investigate the antibacterial efficacy of commonly consumed dietary items. Results and Discussion: This research examined the antibacterial activity of thirteen different daily vegetables and fruits. Among them, the extract from Citrus limon (Eureka) had the highest efficacy as an antibacterial agent against Gram-positive bacteria. The study involved quantifying the antibacterial efficacy of Citrus limon (Eureka) extract by measuring the diameter of the antibacterial zone and determining the cell concentration in the sample using an Ultraviolet Spectrometer. The results revealed a positive correlation between the antibacterial ability of the extract and its quantity, as well as a negative correlation between the inhibition degree of S. aureus and the quantity of Citrus limon (Eureka) extract. Conclusion: The study revealed that the extract derived from Citrus limon (Eureka) has robust antibacterial properties against gram-positive bacteria while demonstrating no discernible effect on gram-negative bacteria.
Health-game: a serious game to inform about coronavirus and combat false information
Authors: Estevam Leonardo , Ferreira Victor , Pontes Paulo , Costa Fernando , Seruffo Marcos
Published: November 2023

The market for digital games in Brazil has been growing prominently in recent years. In this area, educational games have been highlighted, which demonstrate positive results for the practice of gamification in the learning process. This article presents a serious quiz game that aims to inform you about the COVID-19, highlighting the importance of sharing truthful information about the virus. Making use of a methodology for regionalization of information with emphasis on everyday situations, thus intending to combat false information in a practical, scalable and playful way. The results, obtained from the validation with 30 students who tested the game, served as supporting material for improvements in the game and point out that, even using relatively simple and already usual techniques in the serious game scenario, it is possible to innovate in this field and provide society with a tool connected to the moment and difficulties it faces.
Fenótipos digitais para mindfulness e ansiedade encontrados por aplicativo de smartphone
Authors: Meneses Danilo Andrade de , Tavares Joel Jonathan Carvalho , Monteiro Raíssa Ester Maia , Lopez Luiz Carlos Serramo
Published: November 2023

A pesquisa em telemedicina possibilitou a captação de medidas fisiológicas para encontrar biomarcadores

do comportamento humano durante o uso de smartphones chamados fenótipos digitais. A identificação

e avaliação desses biomarcadores para diagnóstico da saúde fornece subsídios a uma área afim da

telemedicina, a medicina de precisão. Foi desenvolvido um aplicativo para celular chamado Neuropesquisa,

que possui recursos voltados a encontrar esses biomarcadores enquanto os usuários preenchem escalas

psicológicas para saúde mental. O objetivo foi correlacionar mindfulness, ansiedade e tempo de reação e

rastrear possíveis fenótipos digitais dessas pessoas. Realizou-se um estudo observacional, de delineamento

correlacional, transversal e remoto com 364 adultos pelo Neuropesquisa. Foram encontradas correlações

positivas e significativas entre mindfulness e tempo de reação, e negativas e significativas para ansiedade

e tempo de reação. Concluiu-se que Neuropesquisa foi capaz de identificar fenótipos digitais dentre os

constructos avaliados, de relevante importância para medicina de precisão e saúde mental.
Effect of new coumarin derivatives on the impulsive and compulsive components of gambling addiction in rats
Authors: Daliev Bakhodir B. , Lebedev Andrei A. , Bychkov Evgeny R. , Shabanov Petr D.
Published: November 2023

BACKGROUND: The search for new neuroactive compounds that selectively affect the mechanisms of emotional reinforcement in gambling addiction is of interest. No previous studies have examined the effects of coumarins on gambling addiction.
AIM: This study aimed to investigate the effect of new coumarin derivatives on the impulsive and compulsive components of gambling addiction in rats.
MATERIALS AND METHODS: The effects of drugs on elements of gambling addiction were assessed in rats in the “marble burying” test and “probability and magnitude of reinforcement” in the three-arm maze, a version of the Iowa test. The effects of the following six coumarin derivatives were assessed: LVM-091, LVM-092, LVM-096, LVM-099, LVM-S144, and IEM-2886.
RESULTS: In the “burrowing balls” test, substances synthesized based on coumarins LVM-092, LVM-099, LVM-S144, and IEM-2886 reduced the level of compulsivity, reducing the number of buried balls compared with the control and diazepam groups (p ≤ 0.05). In the “probability and magnitude of reinforcement” test, after the administration of drugs LVM-091, LVM-099, LVM-S144, and IEM-2886, the level of impulsivity and risk behavior decreased, reducing the number of animals entering the sleeve with the greatest reinforcement and its low probability.
CONCLUSIONS: New coumarin derivatives cause an anticompulsive effect and reduce the impulsivity level in rats, which in the future can be used for treating obsessive–compulsive disorders and addictive conditions, such as Internet addiction and gaming addiction.
Pyolytics as a product of the physical–chemical repurposing of antiseptics and an alternative to larval therapy for chronic wounds
Authors: Urakov Aleksandr L. , Urakova Natalia A. , Reshetnikov Alexey P. , Shabanov Petr D. , Wang Yi , Bodduluri Pradeep Vishwanath , Samorodov Aleksandr V. , Rozov Roman A. , Shchemeleva Albina A. , Novikov Vasiliy E. , Pozhilova Elena V.
Published: November 2023

The traditional treatment of chronic wounds involves daily cleansing of the wound surface from purulent necrotic masses using mechanical and medicinal methods, accompanied by regular replacement of wound dressing. In this case, medicinal wound cleansing lasts 10–15 mins from the time of replacement of the old wound dressing with the new one. According to established practice, medicinal sanitation of infected and purulent wounds during dressing involves irrigation of the wound surface with cleansing solutions, antiseptics, and/or antibiotics. In severe cases, the above therapy is supplemented with live larvae of the necrophage fly, which are injected into purulent necrotic masses and left in them under wound dressing until wounds are completely cleansed from pus. Nevertheless, the generally accepted course of treatment of chronic wounds remains ineffective. The use of pyolytics and their supplementation with wound dressings in the form of warm wet compresses, which create a local greenhouse effect in wounds, was reported to accelerate the healing of chronic wounds. Pyolytics are a group of antiseptics developed in Russia. They are warm alkaline solutions of hydrogen peroxide; when they interact with purulent necrotic masses, these solutions dissolve very quickly and foam them. Because of the interaction with pyolytics, thick purulent masses immediately turn into fluffy oxygenated foam. Pyolytics have been developed because of the physicochemical repurposing of aqueous solutions of sodium hydrogen carbonate and hydrogen peroxide. To accelerate the healing of chronic wounds, a recommendation was to irrigate the surface of chronic wounds with 3% hydrogen peroxide and 2–10% sodium bicarbonate solutions, heated to 37–45°C, which have alkaline activity at pH 8.4–8.5 and are enriched with dissolved carbon dioxide or oxygen (due to excess pressure of 0.2 atm). This study presented the importance of treating chronic wounds using politics and treatment outcomes using pyolytics along with warm moist dressing compresses, demonstrating a wound-healing effect. Consequently, physical and chemical reprofiling of antiseptics may make them effective pyolytics, and the combination of pyolytics with warm wound dressings such as warm moist compresses, which create a local greenhouse effect on wounds, accelerates the healing of chronic wounds.
Functional Near Infrared Spectroscopy (fNIRS) Assessment of State Vs. Trait Eating Behavior
Authors:   , Thomopoulos-Titomihelakis Kristina , Nasser Jennifer
Published: November 2023

Problem: Disordered Eating Behaviors (DEBs) are state-dependent (short-term) behaviors that can lead to trait-dependent (long-term) characteristics over time. The presence of DEBs for those seeking weight loss presents a risk for development of Eating Disorders (EDs); however, using the Eating Disorder Examination-Questionnaire (EDE-Q) Global Score (GS) to verify non-ED status does not allow for identification of DEBs. Objectives: The overarching objective of this work is to use a state-dependent neuroimaging method, functional Near Infrared Spectroscopy (fNIRS), to assess a modified EDE-Q GS for identifying DEBs in a non-ED population. Specifically, this work aims to (1) explore relationships between fNIRS variables, the original EDE-Q GS, and waist circumference, (2) statistically assess the construction of the original EDE-Q GS, and (3) modify the original EDE-Q GS to embed the Behavioral Features (BF) subscale into it. Methods: Secondary data analysis of fNIRS variables and self-reported eating behaviors (GS+BF) was conducted on data from a study examining relationships between regional prefrontal cortex activation and amount of food eaten in a test meal. A modified GS, the Disordered Eating Behavior Screener and Questionnaire (DEBSQ), was developed to include and address BF. GS and DEBSQ were statistically assessed using multiple regression. Results: Data from 97 participants (M=45, W=52) were analyzed. HbR added significantly to the model predicting GS, F(3, 76) = 3.107, p < 0.05, adj. R2 = 0.109. WC predicted GS in models with Oxy and HbO, F (3, 78) = 1.895, p > 0.05, adj. R2 = 0.068 and F(3, 78) = 1.565, p > 0.05, adj. R2 = 0.057, respectively. WC significantly predict DEBSQ in all the multiple regression models and identified 18 participants who endorsed DEBs (as per the BF subscale). Conclusions: Use of fNIRS revealed that using both state- and trait-dependent questions may provide a more comprehensive assessment of eating behavior for individuals not diagnosed with ED. DEBSQ has potential to incite a contemporary approach to potentially identifying DEBs sooner, given that all antecedent EDE constructs (including the BF subscale) are embedded within it. As such, it may also encourage extension of its use in a non-ED population. Additional studies in non-clinical and clinical samples are warranted.
Development of Interactive Web-Based Learning Media with the Discovery Learning Model to Increase Student Learning Motivation in Object Oriented Programming XI Vocational High Schools
Authors: Mustaqim M. Fazal
Published: November 2023

Students have difficulty understanding object-oriented programming material. Because the learning process carried out still uses the lecture method and the learning media used in the form of PowerPoint and even textbooks, resulting in a lack of understanding and a lack of student learning motivation. Other problems arise such as drowsiness due to boring learning, and difficulty understanding due to lack of interaction between students and teachers. Today's technology that can support the learning process in solving these problems is an interactive web. This study uses the Hannafin and Peck development model which goes through 3 phases, namely (1) needs analysis, (2) design, and (3) development and implementation. Data collection techniques were carried out through observation and questionnaires. The learning media developed is in the form of an interactive web application with a discovery learning model that contains learning and evaluation videos. The results of the feasibility analysis of learning media obtained the results of media expert validation of 96.3%, material expert validation of 93%, and group trials of 85.4%. The results of the analysis of all feasibility data obtained an average of 91.6% with the qualification "very valid" and declared feasible to be used in assisting the learning process of students. While the results of the analysis of increasing learning motivation obtained the results of group trials of 0.37. Based on these results, it is stated that learning media can increase students' learning motivation in the learning process with "moderate" qualifications.
Artificial Neural Network-Based Modeling of Performance Spark Ignition Engine Fuelled with Bioethanol and Gasoline
Authors: Marianingsih Susi , Mar’i Farhanna , Nanlohy Hendry Y.
Published: November 2023

Machine learning technology can distinguish the relationship between engine characteristics and performances. Therefore, the goal of the present work is to predict the performance parameters of a single-cylinder 4-stroke gasoline engine at different ignition timings using a blended mixture of gasoline and bioethanol by an artificial neural network (ANN). Experimental data for training and testing in the proposed ANN was obtained at a dynamic speed and full load condition. An ANN model was developed based on standard Back-Propagation algorithm for the spark ignition engine. Multi-layer perception network (MLP) was used for non-linear mapping between the input and output parameters. An optimizer in the family of quasi-Newton methods (lbfgs) and the rectified linear unit function were used to assess the percentage error between the desired and the predicted values. The network input parameters are engine speed, fuel, and ignition timing. Furthermore, torque, power, specific fuel consumption (SFC), thermal efficiency (ηth), and energy consumption (EC) are taken as output parameters. The results show that ANN is the proper method for predicting SIE performance because it has accurate prediction results that are very similar to experimental results. Moreover, from the observation results, the ANN model can predict the engine performance quite well with correlation coefficient (R)=0.962139 and MSE=0.003967 for data testing.
Complications of immunotherapy in advanced hepatocellular carcinoma
Authors: Song Young-Gi , Yoo Jeong-Ju , Kim Sang Gyune , Kim Young Seok
Published: November 2023

Immune checkpoint inhibitors (ICIs) are highly effective in cancer treatment. However, the risks associated with the treatment must be carefully balanced against the therapeutic benefits. Immune-related adverse events (irAEs) are generally unpredictable and may persist over an extended period. In this review, we analyzed common irAEs reported in highly cited original articles and systematic reviews. The prevalent adverse reactions include fatigue, pyrexia, rash, pruritus, diarrhea, decreased appetite, nausea, abdominal pain, constipation, hepatitis, and hypothyroidism. Therefore, it is crucial to conduct evaluations not only of gastrointestinal organs but also of cardiac, neurologic, endocrine (including the frequently affected thyroid), and ophthalmic systems before commencing ICIs. This review further explores commonly reported types of irAEs, specific irAEs associated with each ICI agent, rare yet potentially fatal irAEs, and available treatment options for managing them.
Vulval symptoms in female recreational cyclists
Authors: Harrison Lizzie , Edey Katharine
Published: November 2023

Background: Cycling is linked to altered genital sensation, numbness, pain and sexual dysfunction in males and the professional female cyclist. After noticing an increase in women presenting to gynaecology clinics with cycling related vulval symptoms, we aimed to identify the incidence, significance and management of vulval pathology among female recreational cyclists.
Methods: An anonymous online questionnaire was distributed to 5 Devon cycling clubs and promoted on the “South West Women’s Cycling” Facebook group. Participants were asked about vulval symptoms, management and if these symptoms had affected their cycling.
Results: 508 women responded to the questionnaire between the ages of 20 and 60+. Overall 221, 43.5% of women said they had been deterred from cycling due to vulval/perineal discomfort. The commonest symptom experienced was pain, 37.4%, followed by chafing, 33.3% and redness, 26.6%. Just over a fifth of women had experienced infections they attribute to cycling: 9.8% urinary tract infections, 7.5% vulvovaginal candida and 3.1% bacterial vaginosis. The most important recommendation for the management of vulval discomfort was to use a women-specific saddle with a central cut out. Other recommendations included the benefits of professional bike fit, use of chamois cream and avoidance of hair removal. The menopausal group (the modal group) also commented on the benefits of topical oestrogen to counter the effects of atrophy.
Conclusions: Vulval/perineal symptoms are a significant problem for female recreational cyclists. Further research and randomised control trials into the prevention and management is required so that evidence-based guidelines can be developed.