bluuebunny/crossref_metadata_2025 huggingface dataset:
Hipertensão pseudorresistente causada por inadequação do regime terapêutico
Authors: Nascimento Victor Barbosa , Silva Rosileide Zeferino da , Carvalho Janaina Fraga de , Leopardi-Gonçalves Maria das Graças , Oliveira-Filho Alfredo Dias de , Neves Sabrina Joany Felizardo
Published: July 2022

Fundamento: O diagnóstico da hipertensão arterial resistente (HAR) requer a identificação e exclusão de casos de pseudorresistência, que por sua vez deve-se à (1) má técnica de medição da pressão arterial (PA), (2) efeito do jaleco branco, (3) baixa adesão terapêutica e/ou (4) esquema terapêutico inadequado. Objetivo: Este estudo teve como objetivo avaliar prevalência de hipertensão pseudorresistente (HAPR) causada pela presença de Inadequação do Regime Terapêutico (IRT). Métodos: Foi realizado um estudo transversal com pacientes atendidos na atenção primária em Maceió entre dezembro de 2013 a fevereiro de 2014. Foram incluídos pacientes com diagnóstico de hipertensão e em tratamento medicamentoso. Os pacientes foram avaliados quanto ao uso de medicamentos, análise do esquema terapêutico anti-hipertensivo, adesão terapêutica, valores de Pressão Arterial Sistólica (PAS) e Pressão Arterial Diastólica (PAD). Resultados: Foram incluídos no estudo 183 pacientes, destes 8 (4,3%) apresentaram HAR e 12 (6,6%) apresentaram HAPR. Todos os pacientes com HAPR apresentaram IRT entre os pacientes com HAS primária 74,8% foram expostos a IRT (p=0,000). O tipo de IRT mais frequente entre pacientes com HAPR foi a inércia terapêutica. Conclusão: Deste modo, concluímos que a IRT é recorrente entre pacientes com HAPR, sendo a inércia terapêutica o tipo de IRT mais frequente.
Microbiological analysis of sterile and nonsterile gloves before and during root canal treatment procedures
Authors: Barroso Arthur Pimentel , Silva Emmanuel João Nogueira Leal da , Soares Edy Carlos de Alencar , Anacleto Felipe Nogueira , Prado Marina Carvalho , Guerisoli Danilo Mathias Zanello , Duque Thais Mageste , Marion Jefferson José de Carvalho
Published: July 2022

Objective: To evaluate the microbiological contamination of sterile (SG) and non-sterile (NSG) gloves before and during different stages of endodontic treatment. Methodology: Five brands (n = 10 per brand) of NSG (Supermax, UniGloves, Lemgruber, Nugard and Embramac) and four brands (n = 10 per brand) of SG (Sensitex, Sanro, Mucambo, Madeitex) were analyzed. Microbiological collections were performed at 3 different time-points: immediately after opening the packages (S1); after performing rubber dam placement (S2); and at the end of root canal treatment (S3). In the NSG group, to assess possible contamination by exposure to the clinical environment, samples were also collected within 24 hours (S4) and 7 days (S5) after opening the packages. After smearing the gloves with sterile swabs, the samples were immediately placed in test tubes containing specific BHI culture medium. These samples were incubated for 24 and 48h and the turbidity of the medium was evaluated. For turbid samples, bacterial identification was performed through culture and biochemical tests. Results: At S1, only the NSG UniGloves and Nugard brands showed contamination, while no contamination was observed in the SG. After S2 and S3 all brands showed contamination. In the NSG assessments, 24h after opening the packaging (S4) only the UniGloves brand showed no contamination, but this was not observed after 7 days (S5). The most observed species were Staphylococcus aureus, Staphylococcus ssp, Staphylococcus intermedius, Neisseria ssp, Escherichia coli and Pseudomonas aeroginosa. Conclusion: The NSG can be contaminated after opening the packaging and their exposure to the dental office environment can make it contaminated. SG are sterile but can also become contaminated during procedures. In the trans-operative period of root canal treatment, both NSG and SG can be contaminated by Gram-positive and Gram-negative bacteria.
Prosthetic solution for whistling in fixed prostheses on implants: a case report
Authors: Almeida Eduarda Calisto de , Dias Kátia Denise da Silva Ribeiro Gamba , Oliveira Manuela Ferreira Manhães  de , Valentim Elis Regina Nunes de Almeida , Heggendorn Fabiano Luiz
Published: July 2022

This clinical case report aims to describe the prosthetic solutions in a case of phonetic alteration reported by the patient after multiple anterosuperior rehabilitation with seven single cemented crowns type FP2, responsible for the lispting, reversing the prosthetic rehabilitation in four FP3 splinted and screwed crowns with palatal flange. Initially, the patient was unsatisfied with an upper removable partial denture. After the planning and execution of the surgical phase with eight osseointegrated implants, the osseointegration period occurred with the installation of seven single cemented crowns classified as FP2. During the adaptation period, the patient reported rattling during speech due to the passage of air in the cervical interdental region of the implant-supported prostheses (ISP), corresponding to teeth elements 22 to 12. When identifying the crowns responsible for the rattling, we elaborated a new plan with a FP3 splinted and screwed to guarantee reversibility, plus artificial cervical gum in the palatal region, called flange, replacing the lost anatomical crown and soft tissues. Several factors can result in phonetic changes; in the presented case, the multiple upper anterior prosthetic rehabilitation associated with the existence of a pronounced ogival palate and a thin gingival profile of the patient resulted in the development of whistling. The prosthetic conversion of crowns from FP2 to FP3 with palatal flange ensuring air locking between the cervical region of the FP proved satisfactory in resolving the condition of phonetic alteration, rehabilitating the lost phonemes.
A inclusão escolar pela perspectiva docente: reflexões a partir dos textos legislativos
Authors: Araújo Raianny Kelly Nascimento , Lima Rafael Moreira , Martins Viviane Lima
Published: July 2022

A inclusão social de pessoas com deficiência e principalmente a inclusão escolar, é uma temática que vem ganhando espaço nas discussões nacionais e internacionais, tanto nos projetos políticos pedagógicos como na legislação. Nesse sentido, este trabalho busca compreender como as políticas públicas dão subsídios às práticas educativas de inclusão dos(as) professores(as) que trabalham com estudantes com deficiência. É perceptível que a legislação brasileira assegura o acesso universal à educação de qualidade, mas ainda é deficitária quando pensamos no tema inclusão. Analisando na prática, vemos que falta formação inicial e continuada para os(as) professores(as), recursos humanos e materiais diversos, infraestrutura adequada nas escolas, assim como uma mentalidade inclusiva. A Constituição Federal, as Diretrizes e Bases da educação, o ECA e as Diretrizes Curriculares para a Educação Especial na Educação Básica, são exemplos de legislações nacionais que abordam o direito à educação, ao acesso e a permanência com qualidade nas escolas, entretanto, no que se refere às crianças com deficiência, estas leis divergem com a realidade das escolas regulares, tendo em vista as múltiplas barreiras atitudinais e concretas que as escolas e os(as) alunos(as) vivenciam.
IQA da nascente do Córrego Sussuapara nos meses secos e chuvosos no município de Palmas – TO
Authors: Pereira Jucilene da Costa , Queiroz Sérgio Carlos Bernardo , Picanço Aurélio Pêssoa , Naoe Alessandra Maria de Lima , Silva Roberta Araújo e , Mendonça Rose Mary Gondim , Frota Adréia Cintra Braga
Published: July 2022

As nascentes são sistemas ambientais importantes para a manutenção do equilíbrio hidrológico, geomorfológico e biológico. Porém, em áreas urbanas, essas nascentes têm sido intensamente modificadas pela ação humana. Uma das principais consequências das intervenções urbanas na dinâmica das nascentes são as alterações na qualidade da água. Além disso, períodos de maior precipitação podem interferir nessa dinâmica. Por isso, o presente estudo teve como objetivo avaliar o índice de qualidade das águas – IQA na nascente do Córrego Sussuapara no município de Palmas-TO no ano de 2021. Foram estudados nove parâmetros para avaliar a qualidade da água, sendo quatro amostras coletadas nos meses secos e quatro nos meses chuvosos. Os resultados obtidos foram comparados com a Resolução nº 357 do Conama e demonstraram que o IQA da nascente do Córrego Sussuapara nos meses secos foi superior aos meses chuvosos, sendo classificadas como “Boa” e “Regular”, respectivamente. Os resultados evidenciaram que os impactos causados pelo escoamento superficial e localização da nascente são determinantes para o índice de qualidade da água.
Disseminando cuidado na Atenção Primária à Saúde: a educação permanente como estratégia para prevenção de quedas em idosos
Authors: Morais Cirliane de Araújo , Monte Francisco Thiago Paiva , Félix Sarah Carvalho , Oliveira Camila Martins de , Fontenele Débora Maria Ximenes , Sampaio Maria Auxiliadora Resende , Carneiro Francisca Angelita
Published: July 2022

Pesquisa intervenção, de abordagem qualitativa, sobre o desenvolvimento de um processo de educação permanente em saúde, com a temática da prevenção de quedas em idosos, realizada com Agentes Comunitários de Saúde (ACS) atuantes em um dos territórios da Estratégia Saúde da Família de um município do interior do Ceará. Utilizou-se a observação participante, aplicação de questionários e gravação de áudio como instrumentos mediadores da coleta de dados. Para descrição dos resultados, os dados foram submetidos a análise de conteúdo do tipo análise temática proposta por Minayo. Notou-se um contexto de encontro com algumas dificuldades na compreensão e identificação da equipe sobre os fatores de risco para quedas em idosos. A intervenção propiciou a compreensão sobre estes fatores, bem como sobre as possibilidades de prevenção de quedas, indicando as possíveis necessidades de adaptação que devem ocorrer no ambiente domiciliar. Destaca-se a importância da corresponsabilização da família no cuidado do idoso.
Relação entre as condições de saneamento e os objetivos do desenvolvimento sustentável
Authors: Araújo Wesley Fernandes , Silva Jéssica Alves da , Rocha Filho Luciano Borges da , Rocha Lindalva de Moura
Published: July 2022

O acesso ao saneamento básico foi adotado em 2015 pela Cúpula das Nações Unidas sobre o Desenvolvimento Sustentável como um dos objetivos a serem alcançados globalmente até 2030. Todavia, em uma rápida observação sobre os demais Objetivos se nota que seus alcances também perpassam por melhores condições de saneamento. Este trabalho objetivou identificar os dados obtidos no Instituto Trata Brasil para correlacionar o comportamento da renda, saúde, mortalidade infantil e educação quando se modificam as condições disponíveis de acesso aos serviços básicos, tendo em vista aproximar seus resultados com Objetivos propostos na Agenda 2030. Para tanto, foram determinados os coeficientes de correlação linear e de determinação e para a realização destes cálculos e da construção dos gráficos foi utilizado o software RStudio. As correlações e os coeficientes de determinação calculados se mostraram fortes e capazes de explicar bem a sua variação conforme se alteram as formas existentes de acesso ao saneamento. Em outras palavras, os indicadores tendem a melhorar quando são realizados investimentos no setor e quanto mais a população é provida de acesso à água e a coleta de esgoto.
Comportamento alimentar e estado nutricional de estudantes de uma escola em Brasília/DF
Authors: Silva Walney Fernandes Martins da , Andrade Ana Beatriz de Oliveira , Guimarães Ana Carolina de Faria Silva , Silva Maria Júlia Assumpção Alves da , Bessa Larissa de Freitas Macedo , Dormundo Nerys Cristiane , Maynard Dayanne da Costa
Published: July 2022

Alterações no estado nutricional estão diretamente relacionadas ao consumo excessivo de alimentos, especialmente de processados e ultraprocessados. Isso porque essas fontes alimentares são ricas em sódio, açúcar e gorduras, além de aditivos alimentares. Na infância, o risco de desenvolver deficiências nutricionais é elevado devido ao aumento das necessidades nutricionais, nessa fase também é importante a comensalidade visto que há a formação dos hábitos alimentares. O objetivo da pesquisa é compreender como a alimentação impacta no estado nutricional das crianças de uma escola no Distrito Federal, por meio de um estudo de caso do tipo descritivo e transversal. O trabalho foi realizado com crianças que frequentam uma escola em Brasília, no período matutino, a amostra foi definida por conveniência. A primeira etapa foi realizada por um questionário avaliando hábitos de vida e alimentares e na segunda etapa foram definidos os pontos críticos, na qual obteve como resultado um consumo regular de alimentos in natura, como frutas (65,6%), verduras e legumes (59,4%) e minimamente processados, como o arroz e feijão (46,9%), mas com um alto consumo de alimentos ultraprocessados, especialmente bebidas açucaradas (50%), doces e guloseimas (43,8%). Além disso, a falta de comensalidade na realização das refeições prevalece na maioria das crianças. Porém, a maioria do público apresentou um peso (76,6%), estatura (93,3%) e IMC (56,6%) adequados para a idade. Concluindo que há a necessidade de acompanhamento nutricional de forma periódica e contínua com avaliação do padrão alimentar dentro e fora da escola do público avaliado.
Pengetahuan dan Sikap Masyarakat terhadap Bahaya Tikus sebagai Agen Global Penular Penyakit Zoonosis
Authors: Kusumarini R Shelly , Annadhifa Chandra Luki , Zuhria Farida Puspita , Billa Frida Ayu Salsana , Lestari Putri Dwi
Published: July 2022

Tikus adalah urban animal sekaligus sumber patogen dan reservoir berbagai penyakit yang berbahaya bagi Kesehatan masyarakat. Bentuk penularan penyakit melalui tikus dapat terjadi secara direct maupun indirect. Masyarakat desa Pucakwangi Kabupaten Lamongan umumnya memiliki mata pencaharian sebagai petani dan peternak. Berdasarkan hasil survei permasalahan yang terjadi di desa tersebut adalah intensitas masyarakat untuk bertemu tikus sangat tinggi yaitu 65% khususnya di sawah dan rumah. Disisi lain, tingkat pengetahuan masyarakat terhadap penyakit zoonosis dan Rodent-borne disease masih rendah. Oleh karena itu, pelaksanaan kegiatan pengabdian masyarakat penting untuk dilakukan berfokus terhadap pengetahuan dan sikap masyarakat dalam menghadapi potensi dan resiko bahaya yang ditimbulkan oleh Tikus. Hasil dari kegiatan ini antara lain mampu meningkatkan pemahaman masyarakat sebesar 100%. Kegiatan ini juga dapat mengetahui upaya yang dilakukan masyarakat selama ini dalam menghadapi tikus diantaranya dengan penggunaan racun tikus, lem tikus, jebakan tikus, dipukul dan ditembak. Kegiatan ini merupakan bagian dari pendekatan sistem One health demi terwujudnya Kesehatan masyarakat yang lebih baik. Lebih lanjut, perlu peningkatan partisipasi aktif masyarakat dengan kegiatan pendampingan agar terbentuk sikap kepedulian terhadap penyakit zoonosis.
Perbandingan Sistem Hukum Inggris Dengan Jerman (Refleksi Terhadap Sumber Hukum Dan Penerapan Hukum Indonesia)
Authors: Tampubolon Manotar , Simbolon Putu George Matthew
Published: July 2022

This article explains the differences and similarities between the British legal system and German Law and reflects their application to Indonesian law which was influenced by the swift flow of legalism. The writing uses a normative juridical method with a comparative law approach. Authors use English common law sources along with their application and German civil law along with their application under the stuffenbau theory. The difference between these legal systems is the common law system prioritizes precedent application, while the civil law system prioritizes statutes. Furthermore, these systems also have similarities whereas both systems are applying customs, doctrines, and legal interpretations as to their complementary legal instruments. The authors address that Indonesia needs to apply methods beyond the statute approach, and Indonesia shall take into account customs, doctrines, and interpretations to achieve justice.
Tindak Pidana Pengalihan Obyek Jaminan Fidusia Oleh Debitur (Tinjauan Yuridis Putusan Nomor: Nomor 137/Pid.Sus/2020/PN.Mks)
Authors: Arafat Muhammad Rusli
Published: July 2022

Sejalan dengan pesatnya pertumbuhan dan aktivitas ekonomi, bentuk- bentuk kejahatan Bisnis kini beranekaragam bentuknya. Seperti penggelapan pajak, pembobolan bank melalui komputer atau automatic teller machine, penyalahgunaan ijin perdagangan, tindak pidana dalam masa pembiayaan perjanjian leasing seperti penggelapan kendraan. Tentunya perbuatan di atas berada pada ranah kegiatan hukum perdata atau hukum bisnis. Namun di dalamnya mengandung unsur kejahatan, maka ujungnya adalah menjadi perbuatan pidana. Penelitian ini sangat penting guna menjawab permasalahan penerapan asas lex spesialis derogat legi generalis dalam tindak pidana pengalihan obyek jaminan fidusia dengan menganalisis pertimbangan hukum majelis hakim dalam putusan pengadilan yang telah memiliki kekuatan hukum tetap. Permasalahan dalam penelitian ini yaitu pengaturan tentang tidak pidana pengalihan obyek fidusia berdasarkan hukum positif di Indonesia serta Bagaimana penerapan asas lex spesialis derogat legi generalis oleh majelis hakim dalam tindak pidana pengalihan obyek jaminan fidusia pada putusan Nomor: 137/Pid.Sus/2020/PN Mks. Penerapan asas Asas Lex Specialis Derogat Legi Generalis harus secara cermat di pertimbangkan oleh hakim dalam pertimbangan hukum terhadap perbuatan terdakwa, tindak pidana pengalihan obyek fidusia melekat pada hukum perdata sehingga akibat hukum dari tidak dilakukannya prosedur pendaftaran jaminan fidusia berakibat pada pemenuhan unsur tindak pidana dalam ketentuan pidana pada UU No. 42 Tahun 1999 tentang Jaminan Fidusia.
BUDAYA HUKUM ANTI - ECO SLAPP SEBUAH PERBANDINGAN HUKUM ANTARA INDONESIA DAN FILIPINA
Authors: Manullang Sardjana Orba , Kusumadewi Yessy , Nurwanty Iis Isnaeni , Natsir Andi Elrika , Lestari Diah
Published: July 2022

Keberadaan lingkungan merupakan salah satu tanggungjawab yang harus dilaksanakan manusia, sebab manusia dan makhluk hidup lainnya tidak bisa hidup tanpa lingkungan. Semakin meningkatnya pengetahuan dan teknologi, seharusnya diikuti juga dengan kemajuan tingkat kesadaran manusia terhadap lingkungan yang semakin terancam keberadaannya. Sayangnya, yang memiliki kesadaran hukum akan pentingnya menjaga lingkungan tidak pada semua orang, maka dalam usaha menjaga lingkungan seringkali ditemukan masalah seperti kriminalisasi atau yang dikenal dengan sebutan SLAPP. Tindakan SLAPP pada awalnya bisa dikatakan sebagai sebuah tindakan pembalasan berupa gugatan saja. Di Indonesia sendiri, tindakan SLAPP dapat berupa tindakan kekerasan, kriminalisasi (melalui proses pidana yang tidak layak atau dipaksakan), ancaman kekerasan (intimidasi) dan gugatan perdata. Salah satu tindakan SLAPP yang paling sering dilakukan adalah kriminalisasi dengan tujuan untuk menghambat atau menghalangi partisipasi masyarakat dalam memperjuangkan haknya untuk memperoleh lingkungan yang baik dan sehat. Konsep SLAPP di Filipina sendiri menjelaskan bahwa, suatu tindakan dikatakan SLAPP apabila seseorang (individu), organisasi non pemerintah, lembaga pemerintah atau para pekerja yang berpartisipasi dalam mewujudkan lingkungan hidup yang baik dan sehat melalui proses mekanisme hukum maupun tidak melalui proses mekanisme hukum, mengalami tindakan kekerasan, ancaman (intimidasi) dan kriminalisasi. Maraknya kasus SLAPP yang terjadi baik di Indonesia maupun di Filipina merupakan sebuah peringatan kepada semua pihak mulai dari masyarakat sampai kepada pemerintah untuk segera membentuk suatu kebijakan Anti Eco-SLAPP yang fokusnya untuk melindungi para pejuang lingkungan agar terhindar dari tindakan SLAPP yang sangat merugikan korban, dan terlebih lagi sebagai bentuk pencegahan kerusakan lingkungan yang akan terjadi cepat atau lambat apabila tidak segera ditangani.
PENGEMBANGAN BAHAN AJAR TEKS SURAT UNTUK SMP DARI SURAT � SURAT DI LINGKUNGAN SISWA
Authors: Wiguno Panji Setyo , Kusmana Suherli , Wilsa Jaja , Al�Aiman Maman Noer
Published: July 2022

Penelitian bertujuan untuk mengatasi keterbatasan bahan ajar teks surat dalam mata pelajaran Bahasa Indonesia di SMP/MTs berdasarkan Kurikulum 2013. Banyak teks surat pribadi dan surat dari instansi di daerah tempat tinggal siswa yang dapat digunakan sebagai dasar pengembangan bahan ajar teks surat tersebut. Untuk mencapai tujuan ini digunakan metode penelitian Research and Development dengan tahap penelitian Analysis, Design, Development, Implementation, dan Evaluation (model ADDIE). Dari penelitian ini dihasilkan bahan ajar yang memenuhi kriteria sebagai bahan ajar yang layak untuk digunakan dalam pembelajaran. Dari pengukuran validasi bahan ajar oleh ahli berdasarkan penilaian terhadap komponen isi/materi, penyajian, bahasa, dan grafika diketahui tingkat kelayakan buku ajar termasuk ke dalam kategori Sangat Layak. Demikian pula penilaian dari guru bidang studi terhadap komponen tersebut termasuk ke dalam kategori Sangat Layak. Berdasarkan implementasi penggunaan bahan ajar tersebut diketahui sangat efektif dalam pembelajaran Bahasa Indonesia di SMP. Keefektifan tersebut dapat ditunjukkan dari hasil pengukuran pada kelas eksperimen yang lebih baik daripada kelas kontrol. Berdasarkan hasil tersebut, dapat dinyatakan bahwa bahan ajar Teks Surat yang dikembangkan berdasarkan teks surat pribadi dan teks surat dinas asal instansi di Kabupaten Brebes sangat layak dan efektif digunakan dalam pembelajaran kepada siswa SMP di Kabupaten Brebes Jawa Tengah.
DESAIN PEMBELAJARAN MENULIS TEKS CERPEN MENGGUNAKAN MODEL PEMBELAJARAN INKUIRI BERBANTUAN MEDIA VIDEO ANIMASI DI SMA
Authors: Mira Ningtyas Sekar Suti , Rasyad Sobihah , Rosmaya Elin
Published: July 2022

Penelitian ini dilakukan untuk membuat desain pembelajaran menulis teks cerpen. Rumusan masalah pada penelitian ini yaitu, bagaimana desain pembelajaran menulis teks cerpen dengan menggunakan model pembelajaran inkuiri berbantuan media video animasi di SMA dan bagaimana implementasinya. Penelitian ini bertujuan untuk mendeskripsikan desain pembelajaran tersebut dan mendeskripsikan hasil implementasi. Untuk menyusun desain pembelajaran, penulis menggunakan metode ADDIE. Selanjutnya, desain pembelajaran tersebut divalidasi oleh tiga dosen ahli dan dua guru bahasa Indonesia. Berdasarkan hasil validasi tersebut, diperoleh nilai sebesar 93 % untuk RPP, 98,57 % untuk media video animasi, dan 87,22 % untuk materi yang terdapat dalam video animasi. Seluruh hasil persentase tersebut menunjukkan kriteria sangat valid. Artinya, desain pembelajaran menulis teks cerpen dengan menggunakan model pembelajaran inkuiri berbantuan media video animasi di SMA layak digunakan.Kata kunci: Desain pembelajaran, teks cerpen, dan video animasi.
PENGARUH MEDIA GAMBAR TERHADAP KEMAMPUAN MENULIS TEKS DESKRIPSI PADA SISWA KELAS VII SMP AL-FALAH KOTA JAMBI
Authors: Sonia Adelia Gita , Budiyono Herman , Purba Andiopenta
Published: July 2022

Penelitian ini memiliki tujuan mendeskripsikan dan untuk mengetahui terdapatnya pengaruh dari media gambar berseri terhadap kemampuan menulis teks deskripsi siswa kelas VII SMP Islam Al-Falah Kota Jambi. Berdasarkan aspek dari struktur teks deskripsi yakni identifikasi umum, deskripsi bagian serta penutup. Penelitian ini menggunakan metode kuantitatif jenis eksperimen, dengan desain penelitian menggunakan quasi eksperimental. Subjek dalam penelitian ini yaitu siswa kelas VII.2 yang memiliki peran sebagai kelas kontrol dengan siswa berjumlah 14 orang dan siswa kelas VII.4 yang memiliki peran sebagai kelas eksperimen yang dengan siswa berjumlah 14 orang juga yang dipilih dengan menerapkan teknik Purposive Sampling. Pemerolehan data dalam penelitian ini didapat dengan cara observasi, dokumentasi dan lembar tes. Pada penelitian ini kemampuan menulis teks deskripsi pada siswa menunjukkan hasil posttest kelas eksperimen lebih tinggi dibandingkan posttest kelas kontrol. Hal ini berdasarkan tinjauan rata-rata dari nilai posttest kelas kontrol yaitu sebesar 84,64, sedangkan rata-rata dari nilai posttest kelas kontrol hanya sebesar 68,57. Setelah dilakukan uji analisis data dan juga uji hipotesis dengan bantuan program SPSS 25, terlihat ada pengaruh positif terhadap penggunaan media gambar berseri yaitu pada uji t diperoleh Sig. 0,000<0,05 atau dengan kata lain Ho ditolak dan Ha diterima.
NILAI-NILAI KEHIDUPAN PADA NOVEL PARADIGMA KARYA SYAHID MUHAMMAD DAN PEMANFAATANNYA SEBAGAI BAHAN AJAR DALAM PEMBELAJARAN TEKS NOVEL DI SMA
Authors: Susilo Jimat , Juwanda Juwanda , Dewi Kartika Puspa
Published: July 2022

Salah satu upaya untuk dapat menarik minat baca siswa adalah menemukan bahan bacaan yang diminati serta di dalamnya memuat kompetensi yang harus dicapai oleh siswa. Misalnya yang paling dekat dengan kehidupan sehari-hari siswa yaitu dengan menyimpulkan pesan yang terkandung dalam sebuah novel melalui nilai-nilai kehidupan. Penelitian ini menggunakan metode kualitatif dengan mekanisme kerja deskriptif analitik. Sumber data penelitian ini adalah novel Paradigma karya Syahid Muhammad. Tujuan dari penelitian ini adalah untuk mendeskripsikan nilai-nilai kehidupan yang terdapat dalam novel Paradigma karya Syahid Muhammad dan pemanfaatannya sebagai bahan ajar sastra berupa modul untuk tingkat SMA sederajat. Data yang diperoleh berasal dari hasil analisis novel yang kemudian dimanfaatkan sebagai bahan ajar berupa modul. Selanjutnya, bahan ajar tersebut divalidasi oleh beberapa ahli. Hasil angket validasi dosen ahli dengan nilai persentase 90,79% dan 88,82% serta hasil angket validasi guru ahli dengan nilai persentase 84,87% dan 98,68%. Kemudian, hasil validasi dari dosen ahli dan guru ahli digabungkan sehingga memperoleh hasil dengan nilai persentase 90,79%.
PEMBELAJARAN TEKS CERITA INSPIRATIF MENGGUNAKAN GOOGLE CLASSROOM: MENINGKATKAN PEMAHAMAN SISWA TERHADAP TEKS CERITA INSPIRATIF
Authors: Rahayu Sri , Rozak Abdul , Mascita Dede Endang
Published: July 2022

Penelitian ini bertujuan untuk mengetahui proses, aktivitas, dan efektivitas pembelajaran menggunakan media kelas google, materi teks cerita inspiratif pada siswa SMP Negeri 1 Kasokandel Kabupaten Majalengka. Pembelajaran teks disampaikan dengan media pembelajaran yang sesuai dengan pembelajaran era abad 21 dan sesuai dengan revolusi industri 4.0 yang berbasis teknologi digita. Penelitian ini menggunakan metode eksperimen nonequivalent control group design. Hasil penelitian adalah meningkatnya kompetensi pengetahuan dan keterampilan siswa terhadap materi teks cerita inspiratif. Jadi,media kelas google efektif digunakan dalam pembelajaran teks cerita inspiratif.
NILAI SOSIAL DALAM SOSIAL ANTOLOGI CERITA PENDEK �JURAGAN HAJI�KARYA HELVY TIANA ROSA DAN PEMANFAATANNYA SEBAGAI BAHAN AJAR SASTRA DI SMA
Authors: Hayati Sri
Published: July 2022

Penelitian ini dilatar belakangi bahwa pengembangan bahan ajar masih belum sepenuhnya dilakukan oleh pendidik. Hal tersebut terhalangnya waktu dan kondisi dari pendidik, dalam hal ini pendidik masih menggunakan bahan ajar sebelumnya. Maka dengan demikian hal yang dilakukan adalah mengembangkan bahan ajar teks cerpen dalam nilai sosial dan unsur-unsur pembangun cerpen pendek berupa bahan ajar modul. Diharapkan bagi peserta didik dapat belajar secara mandiri namun tetap terkontrol oleh pendidik. Metode penelitian yang digunakan adalah metode metode pengembangan (Research and Development atau R&D) dengan model ADDIE yang terdiri atas lima tahap penelitian dan pengembangan. Tahap tersebut yaitu sebagai berikut: 1) Analysis (Analisis), Design (Perancangan), Development (Pengembangan), Implemetation (Implementasi), dan Evaluation (Evaluasi). Penggunaan model ADDIE dimaksudkan untuk menyederhanakan penelitian namun akan mengahsilkan penelitian yang efektif dan efisien. Hasil dari penelitian ini peserta didik dapat menambah wawasan dari antologi cerpen dalam modul yang dibuat oleh pendidik, selain efesien waktu karena belajar mandiri. Hasil pengembangan bahan ajar ini pun divalidasi oleh dosen ahli dan guru agar sejauh mana bahan ajar modul dapat digunakan untuk sebagai referensi lain untuk memperoleh hasil pembelajaran secara maksimal.
“Variations on Variations”: History of the Jazz Transformations of the Allegretto from Beethoven’s Seventh Symphony
Authors:   Russian Gnesins’ Academy of Music, Presnyakova Inga A.
Published: July 2022

The history of jazzing the theme of the variations from the Allegretto of Beethoven’s Seventh Symphony began with a revision of its four-measure fragment in the vein of a light-popular style and traversed the path towards a deep transformation, which in all likelihood would be quite congenial to the composer of the original work, as a 50-minute variation cycle. The article discusses three jazz revisions – the potpourri Beethoven Wrote It... But It Swings! by Dolly Dawn and her Dawn Patrol, written in 1939, the composition Beethoven Riffs On created by the John Kirby Sextet in 1941, and the album Beethoven. Allegretto from Symphony no. 7 created by the Jacques Loussier Trio, 2003. The author reveals the typical methods of the stylistic transformation of the original for jazz practice, as well as individual features for each musical example.
The Small Contrapuntal Cycle in the Music of Paul Natorp
Authors:   Institute of Music, Theater and Choreography, Herzen State Pedagogical University of Russia, Volkova Polina S. , Guo Shaoying ,   Institute of Music, Theater and Choreography, Herzen State Pedagogical University of Russia, Huang Zehuan ,   Institute of Music, Theater and Choreography, Herzen State Pedagogical University of Russia
Published: July 2022

The article examines the musical legacy of German composer Paul Natorp (1854– 1924), who has obtained his world recognition chiefly as a Neo-Kantian philosopher. Unlike the other philosophers-composers known to history, such as, for instance, Jean-Jacques Rousseau and Friedrich Nietzsche, the name of Natorp the composer has remained virtually unknown to philosophers, as well as to musicians. Among the thinker’s greatest influences was Plato, whose attitude towards music was shared by Natorp throughout his entire life. Examining music as one of the fundamental laws of the universe, Natorp placed the principle of harmony at the core not only of his life activities, but also of his philosophical studies and pedagogical innovations. The article presents a scholarly analysis of the small contrapuntal cycle in the musical legacy of the philosopher-composer with the example of Paul Natorp’s Three Preludes and Fugues for Piano, which revive the baroque tradition of improvisation. Natorp’s piano compositions correspond to the influences of his era, which demonstrates a constant aspiration towards the attainment of harmony, balance and clarity in the conditions of the dissolving tonal-harmonic connections and free compositional forms. In his compositions, the art of the future is given a special position as a significant unifying and stabilizing component of musical creativity.
The Scene of the Dramatic Culmination in The Tidings Brought to Mary, a Mystery Play by Paul Claudel, from the 1912 Edition. Organization of the Sound Space
Authors:   St. Petersburg State University, Azarova Valentina V.
Published: July 2022

The article examines the sound space in the second scene of Act II, the culminating scene of The Tidings Brought to Mary, the first edition of Paul Claudel’s mystery play. An analysis is made of the composition and dramaturgy of this scene in order to discern the functions of theatrical music as well as the particularities of sound dramaturgy in the sacred space of the mystery play. The author arrived at the conclusion that the organization of the musical space in Act III, Scene 2 has engendered a new understanding of the universal meaning of the mystery in the 20th century.
Depression among Healthcare Workers During COVID-19 Pandemic in Hulu Langat District, Selangor, Malaysia: A Cross-sectional Study
Authors: Sapari Hadita , Selamat Mohamad-Ikhsan , Mohamed Salina , Suli Zailiza , Isa Mohamad-Rodi
Published: July 2022

Background: COVID-19 is a serious threat to the global, not only to health, economy and society but also is a great challenge to HCW’s mental health. A lot of studies were carried out and found HCW’s psychological well-being has been severely affected, especially those in the hospital setting. This study aims to determine the prevalence of depression and the factors associated with depression among HCWs in public health settings during the COVID-19 pandemic.

Methods: A cross-sectional study was conducted at 13 health clinics and one District Health Office in Hulu Langat District. This study was conducted from February 2021 to Mei 2021. A self-administered questionnaire was distributed consisting of three sections (sociodemographic, job characteristics and depression assessment using validated PHQ-9 tool). Descriptive statistics were used to describe the sociodemographic, and multiple logistic regression was used to determine the factors associated with depression.

Result: A total of 291 HCWs were involved in this study. The prevalence of depression among HCWs was 22.7 (95%CI: 22.65, 22.98). Female (Adj. OR=2.01, 95% CI: 1.016, 3.55), stress at work (Adj. OR=3.22, 95% CI: 1.48, 7.02), conflict among colleague (Adj. OR=3.33, 95% CI: 1.72, 6.34) and never attended training or orientation related COVID-19 management (Adj. OR=2.30, 95% CI=1.13, 4.70) were associated with depression.

Conclusion: The prevalence of depression in this study was comparable with international studies conducted during pandemic COVID-19, but was lower than the local prevalence of depression conducted pre-pandemic. A healthy working environment needs to be conducted to ensure psychological well-being and hence alleviate the depression among HCWs.
Wood-Derived Vascular Patches Loaded With Rapamycin Inhibit Neointimal Hyperplasia
Authors: Xie Boao , Zhang Liwei , Lou Chunyang , Wei Shunbo , Li Jing’an , Bai Hualong , Dardik Alan
Published: July 2022

Background: Patches are commonly used to close blood vessels after vascular surgery. Most currently used materials are either prosthetics or animal-derived; although natural materials, such as a leaf, can be used as a patch, healing of these natural materials is not optimal; rhodamine and rapamycin have been used to show that coating patches with drugs allow drug delivery to inhibit neointimal hyperplasia that may improve patch healing. Wood is abundant, and its stiffness can be reduced with processing; however, whether wood can be used as a vascular patch is not established. We hypothesized that wood can be used as a vascular patch and thus may serve as a novel plant-based biocompatible material.

Method: Male Sprague–Dawley rats (aged 6–8 weeks) were used as an inferior vena cava (IVC) patch venoplasty model. After softening, wood patches coated with rhodamine and rapamycin were implanted into the rat subcutaneous tissue, the abdominal cavity, or the IVC. Samples were explanted on day 14 for analysis.

Result: Wood patches became soft after processing. Patches showed biocompatibility after implantation into the subcutaneous tissue or the abdominal cavity. After implantation into the IVC, the patches retained mechanical strength. There was a significantly thinner neointima in wood patches coated with rapamycin than control patches (146.7 ± 15.32 μm vs. 524.7 ± 26.81 μm; p = 0.0001). There were CD34 and nestin-positive cells throughout the patch, and neointimal endothelial cells were Eph-B4 and COUP-TFII-positive. There was a significantly smaller number of PCNA and α-actin dual-positive cells in the neointima (p = 0.0003), peri-patch area (p = 0.0198), and adventitia (p = 0.0004) in wood patches coated with rapamycin than control patches. Piezo1 was expressed in the neointima and peri-patch area, and there were decreased CD68 and piezo1 dual-positive cells in wood patches coated with rapamycin compared to control patches.

Conclusion: Wood can be used as a novel biomaterial that can be implanted as a vascular patch and also serve as a scaffold for drug delivery. Plant-derived materials may be an alternative to prosthetics or animal-based materials in vascular applications.
The Dual Roles of MAGE-C2 in p53 Ubiquitination and Cell Proliferation Through E3 Ligases MDM2 and TRIM28
Authors: Liu Yunshan , Cao Beibei , Hu Liqiao , Ye Jingjing , Tian Wei , He Xiaojing
Published: July 2022

The tumor suppressor p53 is critical for the maintenance of genome stability and protection against tumor malignant transformation, and its homeostasis is usually regulated by ubiquitination. MDM2 is a major E3 ligase of p53 ubiquitination, and its activity is enhanced by TRIM28. TRIM28 also independently ubiquitinates p53 as an E3 ligase activated by MAGE-C2. Moreover, MAGE-C2 is highly expressed in various cancers, but the detailed mechanisms of MAGE-C2 involved in MDM2/TRIM28-mediated p53 ubiquitination remain unknown. Here, we found that MAGE-C2 directly interacts with MDM2 through its conserved MHD domain to inhibit the activity of MDM2 on p53 ubiquitination. Furthermore, TRIM28 acts as an MAGE-C2 binding partner and directly competes with MAGE-C2 for MDM2 interaction, thus releasing the inhibitory role of MAGE-C2 and promoting p53 ubiquitination. MAGE-C2 suppresses cell proliferation in TRIM28-deficient cells, but the overexpression of TRIM28 antagonizes the inhibitory role of MAGE-C2 and accumulates p53 ubiquitination to promote cell proliferation. This study clarified the molecular link of MAGE-C2 in two major E3 systems MDM2 and TRIM28 on p53 ubiquitination. Our results revealed the molecular function of how MAGE-C2 and TRIM28 contribute to p53 ubiquitination and cell proliferation, in which MAGE-C2 acts as a potential inhibitor of MDM2 and TRIM28 is a vital regulator for MAGE-C2 function in p53 protein level and cell proliferation. This work would be helpful to understand the regulation mechanism of tumor suppressor p53.
Saccharides Influence Sperm Quality and Expressions of Motility and Fertilization-Associated Genes in Cryopreserved Sperm of Pacific Abalone, Haliotis discus hannai
Authors: Hossen Shaharior , Sukhan Zahid Parvez , Cho Yusin , Choi Cheol Young , Kho Kang Hee
Published: July 2022

Pacific abalone, Haliotis discus hannai, is a highly commercial seafood in Southeast Asia. The present study aimed to determine the influence of saccharides and vitamins on post-thaw sperm quality, ATP content, fertilization capacity, hatching capacity, and mRNA content of motility and fertilization-associated genes of Pacific abalone. Sperm cryopreserved using saccharides improved the post-thaw sperm quality including motility, acrosome integrity (AI), plasma membrane integrity (PMI), and mitochondrial membrane potential (MMP). However, vitamins (l-ascorbic acid) did not result in any significant improvement in sperm quality. Sperm cryopreserved using saccharides also improved ATP content, DNA integrity, and mRNA content of motility and fertilization-associated genes of post-thaw sperm than sperm cryopreserved without saccharides. Among sperm cryopreserved using different saccharides, post-thaw sperm quality indicators (except PMI) and mRNA content of motility and fertilization-associated genes did not show significant differences between sperm cryopreserved using 3% sucrose (S) combined with 8% dimethyl sulfoxide (DMSO) and sperm cryopreserved using 1% glucose (G) combined with 8% ethylene glycol (EG). However, sperm cryopreserved using 3% S + 8% DMSO showed higher post-thaw sperm quality (motility: 58.4 ± 2.9%, AI: 57.1 ± 3.2%, PMI: 65.3 ± 3.3%, and MMP: 59.1 ± 3.2%), ATP content (48.4 ± 1.8 nmol/ml), and % DNA in tail (2.09 ± 0.20%) than sperm cryopreserved using other saccharides. When sperms were cryopreserved using 3% S + 8% DMSO, the mRNA content of motility (heat shock protein 70, HSP70; heat shock protein 90, HSP90; protein kinase A, PKA-C; axonemal protein 66.0, Axpp66.0; and tektin-4) and fertilization-associated (sperm protein 18 kDa, SP18 kDa) genes were higher than in sperm cryopreserved using other saccharides. However, changes in the mRNA contents of these genes were insignificant between sperm cryopreserved using 3% S + 8% DMSO and 1% G + 8% EG. Taken together, these results indicate that cryopreservation using 3% S + 8% DMSO can improve post-thaw sperm quality and mRNA contents better than other examined cryoprotectants. The present study suggests that 3% S + 8% DMSO is a suitable cryoprotectant for sperm cryopreservation and molecular conservation of this valuable species.
Rational Design of Synergistic Structure Between Single-Atoms and Nanoparticles for CO2 Hydrogenation to Formate Under Ambient Conditions
Authors: Zhai Shengliang , Zhang Ling , Sun Jikai , Sun Lei , Jiang Shuchao , Yu Tie , Zhai Dong , Liu Chengcheng , Li Zhen , Ren Guoqing
Published: July 2022

Single-atom catalysts (SACs) as the new frontier in heterogeneous catalysis have attracted increasing attention. However, the rational design of SACs with high catalytic activities for specified reactions still remains challenging. Herein, we report the rational design of a Pd1-PdNPs synergistic structure on 2,6-pyridinedicarbonitrile-derived covalent triazine framework (CTF) as an efficient active site for CO2 hydrogenation to formate under ambient conditions. Compared with the catalysts mainly comprising Pd1 and PdNPs, this hybrid catalyst presented significantly improved catalytic activity. By regulating the ratio of Pd1 to PdNPs, we obtained the optimal catalytic activity with a formate formation rate of 3.66 molHCOOM·molPd−1·h−1 under ambient conditions (30°C, 0.1 MPa). Moreover, as a heterogeneous catalyst, this hybrid catalyst is easily recovered and exhibits about a 20% decrease in the catalytic activity after five cycles. These findings are significant in elucidating new rational design principles for CO2 hydrogenation catalysts with superior activity and may open up the possibilities of converting CO2 under ambient conditions.
Challenges to establish the diagnosis of aspergillosis in non-laboratory animals: looking for alternatives in veterinary medicine and demonstration of feasibility through two concrete examples in penguins and dolphins
Authors: Desoubeaux Guillaume , Cray Carolyn , Chesnay Adélaïde
Published: July 2022

Aspergillosis remains difficult to diagnose in animals. Laboratory-based assays are far less developed than those for human medicine, and only few studies have been completed to validate their utility in routine veterinary diagnostics. To overcome the current limitations, veterinarians and researchers have to propose alternative methods including extrapolating from human diagnostic tools and using innovative technology. In the present overview, two specific examples were complementarily addressed in penguins and dolphins to illustrate how is challenging the diagnosis of aspergillosis in animals. Specific focus will be made on the novel application of simple testing in blood based on serological assays or protein electrophoresis and on the new information garnered from metabolomics/proteomics to discover potential new biomarkers. In conclusion, while the diagnostic approach of aspergillosis in veterinary medicine cannot be directly taken from options developed for human medicine, it can certainly serve as inspiration.
Return to University Classrooms With Blended Learning: A Possible Post-pandemic COVID-19 Scenario
Authors: Cobo-Rendón Rubia , Bruna Jofre Carola , Lobos Karla , Cisternas San Martin Nataly , Guzman Esteban
Published: July 2022

After more than 2 years of the pandemic caused by COVID-19, a gradual return to face-to-face teaching has been taking place. Therefore, administrators need to establish procedures to facilitate and ensure the quality of teaching during this process. The purpose of this article is to describe the strengths and challenges of implementing Blended Learning (BL). The design used is consistent with a secondary investigation of a narrative review. As a result, several recommendations are presented for building institutional frameworks that enable the implementation of high-quality BL models in the context of a gradual return to face-to-face courses in higher education. From a theoretical and contextual perspective, considerations for transitioning to this model are discussed, based on lessons learned from emergency remote education. We conclude that the present post-pandemic scenario constitutes a pivotal moment for determining the way education is delivered in higher education.
Association of Metabolic Dysfunction-Associated Fatty Liver Disease With Left Ventricular Diastolic Function and Cardiac Morphology
Authors: Peng Dandan , Yu Zhenqiu , Wang Mingwei , Shi Junping , Sun Lei , Zhang Yuanyuan , Zhao Wenbin , Chen Chen , Tang Jiake , Wang Chunyi , Ni Jie , Wen Wen , Jiang Jingjie
Published: July 2022

Background and Aim

Non-alcoholic fatty liver disease (NAFLD) is closely related to cardiovascular diseases (CVD). A newly proposed definition is metabolic dysfunction-associated fatty liver disease (MAFLD), which was changed from NAFLD. The clinical effect of this change on abnormalities of cardiac structure and function is yet unknown. We aimed to examine whether MAFLD is associated with left ventricular (LV) diastolic dysfunction (LVDD) and cardiac remolding and further identify the impact of different subgroups and severity of MAFLD.

Method

We evaluated 228 participants without known CVDs. Participants were categorized by the presence of MAFLD and the normal group. Then, patients with MAFLD were subclassified into three subgroups: MAFLD patients with diabetes (diabetes subgroup), overweight/obesity patients (overweight/obesity subgroup), and lean/normal-weight patients who had two metabolic risk abnormalities (lean metabolic dysfunction subgroup). Furthermore, the severity of hepatic steatosis was assessed by transient elastography (FibroScan®) with a controlled attenuation parameter (CAP), and patients with MAFLD were divided into normal, mild, moderate, and severe hepatic steatosis groups based on CAP value. Cardiac structure and function were examined by echocardiography.

Results

LVDD was significantly more prevalent in the MAFLD group (24.6% vs. 60.8%, p < 0.001) compared to the normal group. The overweight subgroup and diabetes subgroup were significantly associated with signs of cardiac remolding, including interventricular septum thickness, LV posterior wall thickness, left atrial diameter (all p < 0.05), relative wall thickness, and LV mass index (all p < 0.05). Additionally, moderate-to-to severe steatosis patients had higher risks for LVDD and cardiac remolding (all p-values < 0.05).

Conclusion

MAFLD was associated with LVDD and cardiac remolding, especially in patients with diabetes, overweight patients, and moderate-to-to severe steatosis patients. This study provides theoretical support for the precise prevention of cardiovascular dysfunction in patients with MAFLD.