bluuebunny/crossref_metadata_2025 huggingface dataset:
CARDAMOM-FluxVal version 1.0: a FLUXNET-based validation system for CARDAMOM carbon and water flux estimates
Authors: Yang Yan , Bloom A. Anthony , Ma Shuang , Levine Paul , Norton Alexander , Parazoo Nicholas C. , Reager John T. , Worden John , Quetin Gregory R. , Smallman T. Luke , Williams Mathew , Xu Liang , Saatchi Sassan
Published: March 2022

Abstract. Land–atmosphere carbon and water exchanges have large uncertainty
in terrestrial biosphere models (TBMs). Using observations to reduce TBM
structural and parametric errors and uncertainty is a critical priority for
both understanding and accurately predicting carbon and water fluxes. Recent
implementations of the Bayesian CARbon DAta–MOdel fraMework (CARDAMOM) have
yielded key insights into ecosystem carbon and water cycling. CARDAMOM
estimates parameters for an associated TBM of intermediate complexity
(Data Assimilation Linked Ecosystem Carbon – DALEC). These CARDAMOM analyses – informed by co-located C​​​​​​​ and H2O
flux observations – have exhibited considerable skill in both representing
the variability of assimilated observations and predicting withheld
observations. CARDAMOM and DALEC have been continuously developed to
accommodate new scientific challenges and an expanding variety of
observational constraints. However, so far there has been no concerted
effort to globally and systematically validate CARDAMOM performance across
individual model–data fusion configurations. Here we use the FLUXNET 2015
dataset – an ensemble of 200+ eddy covariance flux tower sites – to
formulate a concerted benchmarking framework for CARDAMOM carbon
(photosynthesis and net C exchange) and water (evapotranspiration) flux
estimates (CARDAMOM-FluxVal version 1.0). We present a concise set of skill
metrics to evaluate CARDAMOM performance against both assimilated and
withheld FLUXNET 2015 photosynthesis, net CO2 exchange, and
evapotranspiration estimates. We further demonstrate the potential for
tailored CARDAMOM evaluations by categorizing performance in terms of (i)
individual land-cover types, (ii) monthly, annual, and mean fluxes, and (iii)
length of assimilation data. The CARDAMOM benchmarking system – along with
the CARDAMOM driver files provided – can be readily repeated to support both the
intercomparison between existing CARDAMOM model configurations and the
formulation, development, and testing of new CARDAMOM model structures.
Deep Learning Methods for Flood Mapping: A Review of Existing Applications and Future Research Directions
Authors: Bentivoglio Roberto , Isufi Elvin , Jonkman Sebastian Nicolaas , Taormina Riccardo
Published: March 2022

Abstract. Deep Learning techniques have been increasingly used in flood management to overcome the limitations of accurate, yet slow, numerical models, and to improve the results of traditional methods for flood mapping. In this paper, we review 58 recent publications to outline the state-of-the-art of the field, identify knowledge gaps, and propose future research directions. The review focuses on the type of deep learning models used for various flood mapping applications, the flood types considered, the spatial scale of the studied events, and the data used for model development. The results show that models based on convolutional layers are usually more accurate as they leverage inductive biases to better process the spatial characteristics of the flooding events. Models based on fully-connected layers, instead, provide accurate results when coupled with other statistical models. Deep learning models showed increased accuracy when compared to traditional approaches and increased speed when compared to numerical methods. While there exist several applications in flood susceptibility, inundation, and hazard mapping, more work is needed to understand how deep learning can assist real-time flood warning during an emergency, and how it can be employed to estimate flood risk. A major challenge lies in developing deep learning models that can generalize to unseen case studies. Furthermore, all reviewed models and their outputs, are deterministic, with limited considerations for uncertainties in outcomes and probabilistic predictions. The authors argue that these identified gaps can be addressed by exploiting recent fundamental advancements in deep learning or by taking inspiration from developments in other applied areas. Models based on graph neural networks and neural operators can work with arbitrarily structured data and thus should be capable of generalizing across different case studies and could account for complex interactions with the natural and built environment. Physics-based deep learning can be used to preserve the underlying physical equations resulting in more reliable speed-up alternatives for numerical models. Similarly, probabilistic models can be built by resorting to Deep Gaussian Processes or Bayesian neural networks.
Effectiveness of Sentinel-1 and Sentinel-2 for Flood Detection Assessment in Europe
Authors: Tarpanelli Angelica , Mondini Alessandro Cesare , Camici Stefania
Published: March 2022

Abstract. Inundation is one of the major natural hazards in Europe. The evaluation of the flood hazard and risk is not straightforward mainly due to the monitoring system that is poor or not uniformly distributed in the territory. The ESA Earth Observation Program, including a series of satellites, Sentinels, for the operative observation of the natural phenomenon, e.g. the inundations, can potentially reduce the gap. Sentinel-1 (SAR) and Sentinel-2 (optical) are demonstrated suitable for mapping flooded areas, but despite the medium-high spatial and temporal resolution of the sensors, the mapping of inundated territories is often partial or missing. The objective of this study is to evaluate through a synthetic study the effectiveness of the Sentinel-1 and Sentinel-2 in the systematic assessment of floods in Europe, where the flood events have duration ranging from some hours to a few days. To reach the target, we analysed ten years of river discharge data over almost 2000 sites in Europe and we extracted flood events over some established thresholds, as proxies of flood riverine inundations. Based on the revisit time of the satellites constellations and cloud coverage, we derived the percentage of potential inundation events that Sentinel-1 and Sentinel-2 could be able to observe. Results show that assuming the configuration of a constellation of two satellites for each mission and considering the ascending and descending orbit, on average the 58 % of flood events are potentially observable by Sentinel-1 and only the 28 % by Sentinel-2 due to the cloud coverage.
Crustal structure of the Volgo–Uralian subcraton revealed by inverse and forward gravity modelling
Authors: Ognev Igor , Ebbing Jörg , Haas Peter
Published: March 2022

Abstract. Volgo–Uralia is a Neoarchaean easternmost part of the East
European craton. Recent seismic studies of the Volgo–Uralian region provided
new insights into the crustal structure of this area. In this study, we
combine satellite gravity and seismic data in a common workflow to perform a
complex study of Volgo–Uralian crustal structure, which is useful for further
basin analysis of the area. In this light, a new crustal model of the
Volgo–Uralian subcraton is presented from a step-wise approach: (1) inverse
gravity modelling followed by (2) 3D forward gravity modelling. First, inversion of the satellite gravity gradient data was applied to determine
the Moho depth for the area. Density contrasts between crust and mantle were
varied laterally according to the tectonic units present in the region, and
the model is constrained by the available active seismic data. The Moho discontinuity obtained from the gravity inversion was consequently
modified and complemented in order to define a complete 3D crustal model by
adding information on the sedimentary cover, upper crust, lower crust, and
lithospheric mantle layers in the process of forward gravity modelling, where
both seismic and gravity constraints were respected. The obtained model
shows crustal thickness variations from 32 to more than 55 km in certain
areas. The thinnest crust with a thickness below 40 km is found beneath the
Precaspian basin, which is covered by a thick sedimentary layer. The
thickest crust is located underneath the Ural Mountains as well as in the
centre of the Volgo–Uralian subcraton. In both areas the crustal thickness
exceeds 50 km. At the same time, initial forward gravity modelling has shown
a gravity misfit of ca. 95 mGal between the measured Bouguer gravity anomaly
and the forward calculated gravity field in the central area of the
Volgo–Uralian subcraton. This misfit was interpreted and modelled as a
high-density lower crust, which possibly represents underplated material. Our preferred crustal model of the Volgo–Uralian subcraton respects the
gravity and seismic constraints and reflects the main geological features of
the region with Moho thickening in the cratons and under the Ural Mountains
and thinning along the Palaeoproterozoic rifts, Precaspian sedimentary basin,
and Pre-Urals foredeep.
Android Educational Game: Introduction to Basic Logic for Children
Authors: Irawan Nurul Ria , Fadhliana Nisa Rizqiya , Sari Wahyuni Eka
Published: March 2022

Introduction to Basic Logic aims to develop children's thinking abilities about numbers and quantities to teach activities that are in accordance with the development of their thinking power. Learning in children requires an educational media game facility, one of which is the Educational Game. This educational type game aims to provoke children's interest in learning the subject matter while playing the game. Mobile games can be an alternative in children's learning. Basically children prefer to play rather than learn. This is natural, because child psychology is playing. Based on these problems an educational game application is made for the introduction of basic logic in Android-based children, so that it can produce alternative learning for children. This educational game is intended for children aged 6-7 years because children aged 6-7 years have begun to understand the concept of numbers and develop sensitivity in solving a problem. And trials are carried out using a questionnaire
أثر التحول إلى الأعمال الإلكترونية على التميز في الأداء المؤسسي بالتطبيق على القطاع الصحي بمحافظة الطائف (1442هـ -2021م)
Authors:   أخصائي ادارة صحية ومستشفيات، ماجستير إدارة مستشفيات، صحة بيشة، المملكة العربية السعودية, السبيعي عبد الله فرحان مطلق , عبد الفتاح طلعت رشاد ,   الأستاذ المساعد في قسم الادارة المالية، جامعة بيشة، المملكة العربية السعودية, محمود عبد الحفيظ عثمان ,   استشاري الطب الوقائي (طب المجتمع)، مديرية الشؤون الصحية، بيشة، المملكة العربية السعودية
Published: March 2022

هدفت الدراسة الحالية إلى دراسة مدى توفر البنية التحتية لأنظمة الأعمال الإلكترونية بالقطاع الصحي بمحافظة الطائف. من خلال إبراز العلاقة بين استخدام نظام الأعمال الإلكترونية وزيادة كفاءة منسوبي القطاع الصحي بمحافظة الطائف. استخدم الباحث المنهج الوصفي التحليلي. تكون مجتمع الدراسة من العاملين في القطاع الصحي في محافظة الطائف، والبالغ عددهم (3100) موظف وعينة عشوائية بسيطة مكونة (174) موظف من العاملين في القطاع الصحي بمحافظة الطائف. بناء على طبيعة البيانات، وعلى المنهج المتبع في الدراسة، وجد الباحث أن الأداة الأكثر ملاءمة لتحقيق أهداف هذه الدراسة هي "الاستبانة" وتوصلت الدراسة إلى أن: هناك أثر ذو دلالة إحصائية للبنية التحتية للقطاع الصحي السعودي والتحول إلى الأعمال الإلكترونية بمحافظة الطائف، وقد بلغت نسبة التأثير (33.6%)، هناك أثر ذو دلالة إحصائية لاستعدادات العاملين بالقطاع الصحي السعودي والتحول إلى الأعمال الإلكترونية بمحافظة الطائف، حيث بلغت نسبة التأثير (29.7%)، هناك أثر ذو دلالة إحصائية للتحول إلى الأعمال الإلكترونية وتحقيق التميز في الأداء المؤسسي بالقطاع الصحي بمحافظة الطائف، حيث بلغت نسبة التأثير (34.6%). وأوصت الدراسة بالتالي: تفعيل الإدارة الإلكترونية بشكل كامل في القطاع الصحي، وتحويل جميع الإجراءات الإدارية التي تتم بالطريقة التقليدية إلى الكترونية، ضرورة التعريف بالخدمات الإلكترونية المتاحة بالقطاع الصحي والترويج لها، عن طريق استغلال التقنية كوسائل الإعلام المختلفة وشبكات التواصل الاجتماعي، حيث يتم التعرف إليها من خلال المستفيدين، ومن ثم توسيع دائرة استخدامها، تطوير الإجراءات والعمليات الإدارية بالقطاع الصحي بما يتوافق مع أهداف الإدارة الإلكترونية
Unusual presentation of Endocervical Adenocarcinoma following hysterectomy for high grade CGIN
Authors:   niversity of Nottingham Medical School, Hall Thomas , Phillips Andrew , Schalkwyk Gerhard Van , Bali Anish
Published: March 2022

Cervical carcinoma is the fourteenth most common cancer in the UK with 1 in every 142 women being diagnosed (1). Cervical carcinoma can be subdivided into numerous histological types, of which endocervical adenocarcinoma, represents 20-25% of all cancers (2). The proportion of cervical cancers diagnosed as endocervical adenocarcinomas has increased as the introduction of the cervical screening for squamous precancerous lesions has reduced the number of squamous cell cancers of the cervix. The most common subtype of endocervical adenocarcinoma is associated with human papillomavirus (HPV) type 18 (3). Often these cancers have a diffuse growth pattern and are closely associated with CGIN (adenocarcinoma in situ) making measurement of the extent of disease difficult. Cervical adenocarcinomas are staged according to the (FIGO) International Federation of Gynaecology and Obstetrics) system. Early stage cervical cancer is usually treated increasing radicality of surgical excision whilst advanced cervical cancer is treated with radiotherapy and chemotherapy.
TPE-Nabs Combination Therapy for Severe COVID-19
Authors:   University in Madison, Wisconsin, US, Malkovsky Miroslav
Published: March 2022

The pandemic spread of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires very urgently to identify effective therapies and prophylaxis. This appears perhaps even more imperative, after remdesivir, seemingly the most promising antiviral drug with very potent in vitro activity against SARS-CoV-2, was tested in adults with severe COVID-19 in a randomized, double-blind, placebo-controlled, multi-centre trial with somewhat disappointing results [1] (quote): “In this study of adult patients admitted to hospital for severe COVID-19, remdesivir was not associated with statistically significant clinical benefits.”
Transoral Robotic Surgery and Geriatric Population: Which Benefit?
Authors:   ENT department, CHU UCL Namur – site Godinne, Avenue du Docteur Gaston Therasse 1, 5530 Yvoir Belgium., Samantha Hassid
Published: March 2022

1.1. Purpose: As a result of increased life expectancy, the proportion of elderly patients with head and neck cancer is constantly rising. Transoral robotic surgery has been developed over the last ten years as a minimal invasive surgical procedure. The purpose of this study is to evaluate the place of this technique for elderly patients. 1.2. Methods & material: Study data related to elderly (age over 75 years) patients who underwent TORS between March 2008 and March 2018 were analyzed. 28 elderly patients were included; the different locations were 18 laryngeal (10 glottic and 8 supraglottic), 3 hypopharyngeal, 2 oral cavities and 5 oropharyngeal carcinoma respectively. 1.3. Results: 28 patients, 23 men and 5 women, with an average of 79 years old were successfully operated without external conversion. The 3-year Disease-Specific Survival (DSS) rate is 87.3% and the 3-year overall survival (OS) rate is 65,6%. Surgery was completed in a mean of 131 minutes (including exposure). All patients were extubated the same day (56%) or the day after the surgery (44%). Except for total laryngectomies, three patients (10.7%) received transient tracheostomies. Oral feeding was started after an average of 11 days after surgery. The hospitalization stay was 27 days on average. 1.4. Conclusions: Trans-oral Robotic surgery is a valuable technical option to address selected head and neck carcinoma in the elderly population. Early postoperative rehabilitation limits swallowing disorders and pulmonary complications. The surgical time is reduced compared to conventional open surgery which is a great advantage for this fragile population.
Favorable surgical outcomes and perioperative complication rates after robotic radical cystectomy and intracorporeal urinary diversion at a single, low-volume center: Initial experience with 65 consecutive cases
Authors:   Department of Urology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 5011194, Japan., Koie Takuya
Published: March 2022

1.1. Purpose: This study aimed to evaluate the surgical outcomes and perioperative complications among patients who underwent robot-assisted radical cystectomy (RARC) with intracorporeal urinary diversion (ICUD). 1.2. Methods & materials: We retrospectively reviewed the clinical and pathological records of 65 consecutive patients who underwent RARC with ICUD between November 2018 and June 2021 at Gifu University. The patients were divided into three groups according to the type of urinary diversion: ureterocutaneostomy (UC), ileal conduit (IC), and ileal neobladder (NB). The endpoints of this study were surgical outcomes and perioperative complications according to the type of UD. 1.3. Results: There were no significant differences between the IC and NB groups with respect to the total operation time. TwentyPage -01 World Journal of Clinical Surgery Open Access https://www.wjclinicalsurgery.com seven complications were registered in the first 90 days. The most frequent early complication was urinary tract infection in 11 patients. 1.4. Conclusion: Our initial experience with RARC followed by ICUD was favorable, with acceptable surgical outcomes and perioperative complications.
Laparotomy in Children in a Tertiary Hospital in a Developing Country: Indications, Complications and Outcome
Authors:   Department of Surgery, Enugu State University Teaching Hospital, Enugu, Nigeria., Emeka Chukwubuike Kevin
Published: March 2022

Background: Pediatric laparotomy is important surgical procedure necessary for the diagnosis and treatment of abdominal surgical conditions in children. The objective of this study was to evaluate our experience on pediatric laparotomy in terms of indications, complications and outcome. Methodology: This was a retrospective study of children aged 15 years and younger who had laparotomy (for various indications) between January 2017 and December 2018 at the pediatric surgery unit of Enugu State University Teaching Hospital (ESUTH) Enugu, Nigeria. Results: A total of 202 pediatric laparotomies were performed during the study period. There was male predominance and the median age of the patients was 5 years. Majority of the patients were infants and most of the laparotomies were performed as emergency surgeries. The mean duration of hospital stay of the patients was 10 days and abdominal pain was the most common symptom. At presentation, one-half and one-quarter of the patients had low hemoglobin and electrolyte derangement respectively. Abdominal ultrasound and x rays were diagnostic in about 50% of the patients. Intussusception was the most common indication for laparotomy and surgical site infection was the most common post-operative complication. Eleven (5.4%) patients expired. Conclusion: Laparotomy in children can be lifesaving and infants with intussusception were the largest group of patients in the current series. Abdominal pain, Page -01 World Journal of Clinical Surgery Open Access https://www.wjclinicalsurgery.com anemia and electrolyte derangement were the common indices at presentation. Pediatric laparotomy can be associated with morbidity and mortality.
In Vitro Bioactivity Test of Senna Alata (L.) Roxb Leaves Extract
Authors: Rahmawati Fri , Prihantini Nur Nunu , Hady Bella Christina
Published: March 2022

Traditionally, Senna Alata (L.) Roxb (Ketepeng Cina) has been used as an alternative medicine for typhus, diabetes, malaria, herpes, eczema, asthma, stomach ulcers, syphilis, influenza, bronchitis, intestinal worms, fungal skin diseases such as tinea versicolor, ringworm and scabies. The study's objective was to determine the active compounds, antioxidant potency and antifungal activity of Senna Alata (L.) Roxb leaves extract. Samples were extracted using the maceration method with 70% ethanol, ethyl acetate and N-hexane as solvents. Phytochemical analysis used the Harbone method, antioxidant testing using 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and antifungal testing using the agar diffusion method. Phytochemical results proved that all Senna Alata (L.) Roxb leaves extract contained alkaloids, saponins, tannins, flavonoids, triterpenoids, steroids, glycosides. While the antioxidant test stated that ethanol and ethyl acetate solvents had solid antioxidant potential with the Inhibition Concentration (IC50) values ​​obtained were 66.01 ppm and 78.23 ppm respectively. While the solvent N-hexane has a moderate antioxidant potential, the IC50 value obtained is 138.80 ppm. The diameter inhibition zones of ethanol, ethyl acetate, and N-hexane extracts against the Candida albicans were 8.66 mm, 10.22 mm and 8.84 mm, respectively. Cryptococcus neoformans was only inhibited by ethyl acetate and N-hexane Senna Alata (L.) Roxb leaves extracts with diameter inhibition zones of 4.84 mm and 4.44 mm, respectively.

Key words: Antifungal, Antioxidant, Candida albicans, Cryptococcus neoformans, Phytochemical , Senna alata (L.) Roxb.
Medical Students’ Knowledge Level about X-Ray as a Diagnostic Support Tool at Universitas Kristen Indonesia, Jakarta Batch 2016
Authors: Marvellini Richard Yan
Published: March 2022

The study is aimed at investigating the medical students’ knowledge level about x-ray as a diagnostic support tool. It was done at Universitas Kristen Indonesia. The type of research is in the form of quantitative descriptive, which aims to systematically, factually, and accurately regarding the level of knowledge. Research data collection was carried out using a cross-sectional research design. The population in this study were all medical students of the Universitas Kristen Indonesia, batch 2016. The respondents were medical students, batch 2016 semester 1, who had just graduated from high school and entered the university level to see respondents' level of knowledge about X-rays for about 100 respondents. The instrument of this study was a set of questionnaires which had been tested to 30 UKI students from the 1st semester of pediatric medicine faculty. Researchers carried out data processing through editing, coding, processing, and cleaning stages. The researcher used univariate and bivariate analysis to analyze the research results. The result of the research is that most of the respondents have a high level of knowledge of X-Ray, and the source most often used by students to find information about X-Ray is electronic media. Based on the bivariate analysis results, the p-value obtained is 0.000, which means that there is a significant relationship between the respondent's school origin and the level of knowledge of X-rays.

Key words: X-Ray, Diagnostic Support Tool, Students’ Knowledge.
Profitability and Determinants of Edible Insects Marketing in Oji-River and Udi Local Government Areas, Enugu State, Nigeria
Authors: C. I Ezeano, , Z. F. Anyanwu, , C. C. Okeke,
Published: March 2022

The study examined the profitability and determinants of edible insects marketing and utilization in Oji-River and Udi Local Government Areas, Enugu State, Nigeria. Specifically, it described the socio-economic characteristics of the respondents, estimate the profitability of edible insect marketing and determined the influence of socio-economic characteristics of the respondents on net marketing income. Purposive sampling technique was used to select 120 respondents and data collection was on primary source using well structured questionnaire and were analyzed using descriptive statistics, enterprise budgeting, Shepherd-Futrell and multiple regression techniques. Finding on socioeconomic characteristics showed that majority of the marketers (35.83%) are within the age bracket of 41-50 years with mean age of 39% and there is female (80.83%) dominance in the enterprise. Profitability indicators such as; net marketing income (N,736,952.83), input cost (cost of harvesting and marketing) (N3,223,247.15), return on investment (N2.159), net return on investment (N1.15) and coefficient of marketing efficiency (0.463) proved the enterprise profitable. The implication of the net return on investment figures revealed that the marketers return N1.15 for every 1 naira invested in the business. Findings also indicated marketing efficiency level of 46.30%. It implies that the marketers are less efficient in marketing of edible insect. Age, gender, household size, other source of income and marketing cost significantly determined net marketing income realized by the edible insect marketers. However improvement in the marketing strategy which will benefit the harvesters/marketers and provision of modern storage and preservative facilities by the union and other relevant agencies for a longer period of time were recommended.

Keywords: Profitability, determinants, marketing and edible insects.
Development of Interactive Learning Multimedia "Mejabando" for Improving Critical and Creative Thinking Skills in Indonesian Language Learning Class V Elementary School
Authors: Sandang Gebriela , . Wagiran , Latiana Lita
Published: March 2022

This study aims to produce android-based learning multimedia. The research method used is R&D research with the ADDIE development model (analysis, design, development, implementation, evaluation). The steps in the research include analyzing, designing, developing, implementing, and evaluating. Data collection techniques in this study include interviews, questionnaires, tests, and documentation. The trial was carried out using the One Group Pretest-Posttest Design. The results of this study are (1) the need for multimedia mejabando learning in the high category (2) the validity of the interactive multimedia mejabando from the material expert got a score of 4.18 in the good category and 4.64 from the material expert in the good category (3) multimedia practicality is in the very practical category with a score of 87%, 88% and 89% (4) the effectiveness of interactive multimedia learning mejabando can be seen from the results of the students' pretest and posttest. Critical thinking skills get an N-Gain score of 0.66 in a fairly effective category and N-Gain score for creative thinking skills of 0.57 in a moderately effective category. Based on the results of the research obtained, it can be concluded that the interactive multimedia mejabando learning to improve critical and creative thinking skills in learning Indonesian for fifth-grade elementary school is practical, valid and effective for use in learning.

Keywords: Multimedia, critical thinking, creative thinking, Indonesian Language.
Association of Demographic Characteristics and Utilization of Cervical Cancer Screening Services among Women in Ikwerre, Southern Nigeria
Authors: C. Okachi-Ordu, , O.B. Nworuh, , J.C. Nwaokoro,
Published: March 2022

Cervical cancer is the leading cause of cancer deaths among women in developing countries. This was a cross-sectional descriptive study carried out to investigate the utilization of cervical cancer screening services among women in Ikwerre, Southern Nigeria. The multi stage sampling technique was used to select 399 women between the ages of 21 and 65years for this study. A well-structured questionnaire after being validated and tested for reliability was administered to the participants. An informed consent was also obtained from all the participants in this study. Chi-square was used to test the relationship between variables at p=0.05 significant level. Results showed that demographic characteristics found to be associated with utilization of cervical cancer screening services in this study were age 12(12.4%) at P= 0.001, marital status 14(9.5%) at P= 0.002, education 19(9.0%) at P= 0.001, number of children 14(6.8%) at P= 0.009 and income level 19 (45.2%) at P= 0.001. From the findings of this study, utilization of cervical cancer screening services among women in Ikwerre was abysmally low. It was recommended that medical personnel play a major role in enlightening the public on the importance of cervical cancer screening and availability of the screening services. The government should also ensure that the cost of the screening service was made affordable.

Keywords: Cervical cancer, Screening, Demography, Utilization.
Analisis kemampuan calon guru IPA mengintegrasikan teknologi dalam pembelajaran menggunakan SAMR
Authors: Abdurrahman Dudung , Nursafitri Nursafitri
Published: March 2022

Pembelajaran di masa pandemi Covid 19 mengharuskan guru memiliki kemampuan dalam teknologi untuk mendukung pembelajaran. Pembelajaran model ini menjadi new normal dalam pendidikan. Oleh karena itu, calon guru harus memiliki kemampuan mengintegrasikan teknologi dalam pembelajaran. Penelitian ini bertujuan untuk menganalisis kemampuan calon guru IPA dalam mengintergasikan teknologi dalam pembelajaran IPA. Metode penelitian yang digunakan adalah deskriptif. Sampel pada penelitian ini adalah mahasiswa yang mengikuti perkuliahan microteaching semster ganjil 2021/2022 sebanyak 6 orang. Pofil kemampuan Â calon guru IPA dalam mengintegrasikan teknologi diperoleh dari observasi pembelajaran yang disimulasikan. Tingkatan integrasi teknologi dalam pembelajaran dikelompokan menggunakan SAMR. Hasilnya diperoleh bahwa mahasiswa calon guru IPA dalam mengintegrasikan pembelajaran masih berada pada tingkat subtitution. Pada tingkat ini, teknologi digunakan pada pembelajaran hanya sebatas pengganti dan tidak ada peningkatan fungsional teknologi di pembelajaran.
Studi literatur: Analisis permasalahan pembelajaran kimia SMA pada materi stoikiometri
Authors: Ahmad Listia Fauziyyah
Published: March 2022

Hingga saat ini problematika miskonsepsi dan kesulitan siswa dalam memecahkan masalah numerik pada topik stoikiometri masih terjadi. Sebagian besar fokus penelitian hanya ditujukan pada cara mengungkap miskonsepsi siswa, padahal mengidentifikasi penyebab dan memberi solusi untuk mengatasi hal tersebut tidak kalah pentingnya. Kesulitan dalam stoikiometri disebabkan kurangnya pemahaman konsep mol, ketidakmampuan menyetarakan persamaan kimia, penggunaan hubungan stoikiometri yang tidak konsisten, mengidentifikasi pereaksi pembatas, penentuan hasil teoritis, dan identifikasi zat yang berlebihan. Pendidik perlu menganalisis serta menerapkan teknik pedagogis sebagai sarana untuk mengatasi miskonsepsi dan kesulitan siswa dalam memecahkan masalah numerik diantaranya memperbaiki prakonsepsi siswa, pembelajaran dengan model student centered learning, membuat peta konsep dan mind map, berlatih memecahkan soal dengan langkah-langkah algoritmik dan melakukan pembelajaran yang mencapai tingkat ketuntasan. Karena eberhasilan siswa dalam memahami materi stoikometri menjadi faktor penentu dalam mempelajari materi selanjutnya yang memerlukan konsep stoikiometri sebagai materi prasyarat.Kata kunci:Â Â  stoikiometri, miskonsepi, kesulitan belajar, kompetensi pedagogik, pemecahan masalah
Examination of Intercultural Sensitivity Levels of Nursing Students
Authors: KABU HERGÜL Filiz , GÖK Fadime , İPİÇÜRÜK Hilal Gizem
Published: March 2022

The aim of this descriptive study was to determine the intercultural sensitivity levels of nursing students. The universe of the study consisted of all students (n=811) studying in the nursing department of a University's health sciences faculty in the 2019-2020 spring semester. All students (n=360) who agreed to participate in the study without sampling were included in the sample. Data were collected with "Student Descriptive Information Form" and "Intercultural Sensitivity Scale. Data were evaluated with number, percentage, mean, standard deviation, Independent Samples t-test, One-Way Anova, Mann Whitney-U and Kruskal Wallis tests. The mean age of the students was 20.01±1.41 and 81.4% were women. When the descriptive characteristics of the students and the Intercultural Sensitivity Scale mean score were compared, It was determined that there was a statistically significant difference between gender and having friends from different cultures. It was observed that female students were more respectful to cultural differences, while males were more self-confident in intercultural interaction. It was determined that students who have friends from different cultures have higher participation in intercultural interaction, self-confidence in intercultural interaction, enjoyment of intercultural interaction and intercultural sensitivity. It was determined that the students included in the study had a moderate level of intercultural sensitivity in general. In addition, when viewed according to the scale sub-dimension; It was determined that while the students used the sub-dimension of participating in intercultural interaction the most, they used the sub-dimension of paying attention to intercultural interaction the least.
The Effect of Using Reading Short Story in Students’ Vocabulary Mastery at SMP HKBP Pajak Baru Belawan
Authors: Aritonang Melly Stevani , Manik Sondang
Published: March 2022

This research was aimed to answer the question about the implementation of short story technique whether it can enrich the students’ English vocabulary at Class VIII SMP HKBP PAJAK BARU BELAWAN or not, This is an experimental research. the writer tested the null hypothesis (Ho) which stated that the use of short story cannot enrich the students’ English vocabulary at Class VIII,.The text that used for short story technique in this reseacrh was monologue text (a text that displays story teller) this research focused on narrative text (imaginative experiences) particularly, narrative text was related to the syllabus of the second semester for second grade of junior high school. After the Pretest, Treatment and Post test, there is a significant difference of mean score got both of experimental group (75.25) and the control group (72,75). T-observe > T – table ( P = 0,05) df (38), or 4,46 > 1,686 (P = 0,05). It means that alternative hypothesis (Ha) is accepted and null hypothesis (Ho) is rejected. Thus it can be conclude that by using Reading Short Story affects the students’ vocabulary masterthat there is a significant effect of Reading Short Story in students’ vocabulary mastery. In other words, alternative hypothesis (Ha) is accepted and null hypothesis (Ho) is rejected
Keywords: implementation of short story technique,reading short story
Android Based Educational Game in Learning and Teaching English Vocabulary
Authors: Insani Nurchintyawati, S.Pd.,M.Pd
Published: March 2022

Vocabulary learning is often perceived as boring by learners, especially for those who grew up in the digital era. The use of online games in vocabulary learning and teaching can be one solution to solve this problem. Android is the current world-famous software nowadays. It is believed to help teachers in delivering knowledge effectively and efficiently. Therefore, this paper aims to illustrate the effectiveness of Android-based educational games to enhance the ability of learners in learning English vocabulary. The discussion includes overview about vocabulary, games, ICT tools in EFL classroom, and the use of educational games from Android (App Inventor) can improve students' English competence in learning vocabulary. Therefore, this paper will be explained about the use of Android-based educational games as one of the fun alternative teaching innovations to support creative teachers and students. And hopefully it can be useful and meaningful reference and information for the reader about the use of android based educational game in learning and teaching English Vocabulary.

Keywords: Android based educational game, vocabulary, ICT tool.
Case Study of Digital-Based Service Innovation for Old Age Insurance (JHT) Claims by BPJS Employment (BPJAMSOSTEK) Pekalongan Branch Office Central Java
Authors: Sofiana Maya , Seiver Langelo Juandy , Supriyadi Endang , Maulina Anita , Wahyuni Rita
Published: March 2022

Various government efforts to break the Covid-19 chain have also affected the economy, as many companies have laid off employees on a large scale. This has resulted in an increase in the number of claims for the Social Security Administering Body (BPJS) for Employment or BPJAMSOSTEK. The purpose of the study was to find out a Case Study of Digital-Based Service Innovation for Old Age Security Claims (JHT) by BPJS Ketenagakerjaan (BPJAMSOSTEK) Pekalongan Branch Office, Central Java. Research methods. The research method used to describe the problems that exist in this study is a qualitative method with a study approach. Primary data sources in this study came from interviews with informants. The informants in this case are employees who are directly involved in the implementation of public services, leaders and participants as users of services provided by BPJAMSOSTEK Pekalongan City Branch, Central Java. The technique used in this study was carried out in several steps, namely, data reduction (sorting, focusing and attention), data presentation (display) and drawing conclusions. Research result. The innovation attributes at BPJAMSOSTEK Pekalongan City Branch are in accordance with the relative advantage, suitability, complexity, possibility to try and ease of observation. In terms of acceptance of the information system, it is seen from 2 elements, namely the ease of use and the usefulness of the LAPAKASIK information system in accordance with the Theory Technology Acceptance Model (TAM): In the Internal User/BPJAMSOSTEK Aspect In the External Aspect User/BPJAMSOSTEK Participant.
Sustainable SCM Approach as a Branding Strategy on the Hutan Bambu Tourism Object in Bekasi City
Authors: Andayani Wuwuh , Fahriyah Aramia , Yoseph Rochland , Andamisari Dessy , Chairani Ridfa
Published: March 2022

This study was aimed at analyzing the implementation of the Sustainable Supply Chain Management (SSCM) approach as a branding strategy of tourism development of Hutan Bambu in Bekasi city. This study employed a descriptive research method using a qualitative approach. The data sources were primary and secondary data. The techniques of data collection were observation, interviews, and documentation. The interviews were conducted with six informants representing the manager, visitors, local communities, and food sellers in the Hutan Bambu area of Bekasi city. Furthermore, the data were analyzed by using the SSCM approach. The results of the study showed that the branding strategy for developing the Hutan Bambu tourism object can apply several ways. First, it considered SSCM concerns, especially sustainability, marketing-logistics empowerment, market-driven SCM, synchronous SCM, fast response logistics, and network-based resource management. Second, the tourism development was carried out by creating strong branding with the advantages of the Hutan Bambu tourism object, namely by marketing through social media to local and national communities. Third, the development can be done by holding attractive soft skills programs regularly by collaborating with training studios or certain institutions, so they can bring in visitors on a more regular and programmed basis. Fourth, this can also be done by modifying the management system, so the tourists can find alternative tourism objects in the city. Finally, the SSCM approach could be implemented in the development of the Hutan Bambu tourism object, Bekasi by strengthening branding and interesting soft-skills, as well as modifying the management system.
Determinant of Customer of Loyalty in Healthcare Industry : Mediating Role of Customer Trust
Authors: Mubarok Endang Saefuddin , Kurniawan Arif , Hidayat Rahmat , Hia Ahman Kuktur , Bandawaty Euis
Published: March 2022

This research aimed at understanding the effect of service quality, clinic image, and price/tariff on patient trust and loyalty. The multivariate analysis with descriptively and explanatorily-quantitative method was used for this research. The samples of the research were 120 respondents. Data collection was carried out using a questionnaire instrument and was subsequently analyzed by using Structural Equation Modeling (SEM). The results of this research concluded that the service quality and price/tariff had a significant effect on trust and clinic image had no significant effect on patient trust. The quality of service, clinic image, and price/tariff had a significant effect on patient loyalty, while trust had no significant effect on patient loyalty. Trust can mediate the effect of clinical image on patient loyalty. However, trust cannot mediate the effect of service quality and price/tariff on patient loyalty. The strength value of the dependent variable shown by the calculation of multiple correlation values (R2), both trust and patient loyalty are significant.
Macroeconomic effects of shocks to import and services sector prices
Authors:   Bank of Greece, Papageorgiou Dimitris
Published: March 2022

This paper investigates the macroeconomic implications of inflationary shocks that originate from the import and services sectors. The set-up is a medium-scale Dynamic Stochastic General Equilibrium (DSGE) model calibrated for the Greek economy. The results suggest that a temporary increase in import price inflation adversely affects economic activity and drives up domestic inflation. The largest output losses occur in the medium term, since in the short term the adverse effects are dampened by the presence of price rigidities and an import substitution effect that induces expenditure to switch towards domestically produced goods. Additionally, the findings suggest that a temporary increase in the price of the services sector exerts strong inflationary pressures and negatively affects economic activity. Finally, the results show that inflation persistence matters for the effects on the macroeconomy. The more persistent inflation is in imports and the services sector, the larger the output losses.
Sistem Manajemen Kartu Nama dengan OCR dan Ekstraksi Informasi Otomatis
Authors: Darmawan Robby , Nasuha Aris , Zaman Lukman , Armanto Hendrawan
Published: March 2022

Sebagai pelaku bisnis, kartu nama adalah salah satu hal yang penting untuk bertukar informasi. Namun kartu nama biasanya mudah hilang atau rusak, sehingga beberapa orang biasanya menyimpan informasi dari kartu nama itu pada telepon genggam atau komputer mereka. Penelitian ini akan membuat sistem manajemen kartu nama baik individu dan juga perusahaan dengan ekstraksi informasi kartu nama otomatis untuk mempermudah pengguna perorangan ataupun perusahaan dalam melakukan penyimpanan kartu nama para kolega. Untuk mewujudkan aplikasi yang dilengkapi dengan fitur tersebut dilakukan proses pengenalan karakter pada gambar kartu nama menggunakan Tesseract OCR dan information extraction memanfaatkan klasifikasi entity dengan membangun classifier menggunakan Naive Bayes dan mengkombinasikannya dengan rule based. Hasil uji coba yang telah dilakukan mendapatkan performa 85.1% untuk pengenalan karakter dan 86% untuk pengklasifikasian entity. Dilakukan juga uji coba fungsionalitas terhadap setiap fitur pada sistem ini dengan menggunakan metode blackbox testing yang memastikan setiap aksi yang dilakukan pengguna akan menghasilkan output sesuai target yang diharapkan. Selain itu, dari hasil kuisioner yang berisikan tentang usability dari sistem ini, sebagian besar responden merasa terbantu dalam memanajemen kartu nama dengan menggunakan sistem aplikasi ini.
Avanços Científicos em Ciências Farmacêuticas
Authors:   Emanuel Tenório Paulino
Published: March 2022

Esta obra trata dos recentes avanços no campo das ciências farmacêuticas, traz como foco desta edição revisões com interesse na ciência farmacêutica empenhada na contribuição para a produção e inovação visando a prospecção para uso terapêutico e/ou marcadores fitoquímicos, o livro traz ainda a relevância da temática de compostos de diferentes origens: compostos naturais e derivados sintéticos inserindo-os nas doenças clinicamente relevantes no contexto contemporâneo.
NOVOS ALVOS FARMACOLÓGICOS E SEUS CANDIDATOS À FÁRMACOS COM ENFOQUE NOS PRODUTOS FINAIS DA GLICAÇÃO AVANÇADA (ANTI-AGES): PERSPECTIVAS PARA O TRATAMENTO DA SÍNDROME METABÓLICA, PARTE I
Authors: Paulino Emanuel Tenório , Silva-Júnior Edeíldo Ferreira , Júnior João Xavier Araújo , Ribeiro Êurica Adélia Nogueira
Published: March 2022

As síndromes metabólicas são doenças relacionadas aos distúrbios cardiovasculares e endócrinos de maneira simultânea manifestando sintomas de característicos associada ao aparecimento de ao menos três doenças concomitante, dentre elas: Hipertensão arterial sistêmica, Diabetes mellitus, dislipidemias, obesidade e/ou infarto agudo do miocárdio, aumentando o risco de mortalidade. O aumento dos níveis circulantes dos produtos finais da glicação avançada (AGES) engatilham o dano cardiovascular e endocrinológico. Assim, o objetivo deste trabalho foi realizar uma revisão de AGES como um novo alvo terapêutico relevante para compor o desenvolvimento de novos fármacos em farmacologia cardiometabólica. Para isto, a busca ativa foi realizada nas bases de dados científicos sem data limite entre as publicações. Os descritores utilizados foram: “Advanced Glycation End-products” and/or “new drugs-design” and/or metabolic syndrome. Os resultados revelaram que os protótipos de fármacos em desenvolvimento envolvem os inibidores da formação de AGES nas fases enzimáticas e não-enzimática, moduladores de receptores para AGES, inibidores da translocação de AGES e compostos antioxidantes. Em conclusão identificamos que AGES é um novo alvo farmacológico explorado para o desenho e desenvolvimento de novos fármacos na síndrome metabólica baseada no uso racional de medicamentos.
NOVOS ALVOS FARMACOLÓGICOS E SEUS CANDIDATOS À FÁRMACOS COM ENFOQUE NOS PRODUTOS FINAIS DA GLICAÇÃO AVANÇADA (ANTI-AGES): PERSPECTIVAS PARA O TRATAMENTO DA SÍNDROME METABÓLICA, PARTE II
Authors: Paulino Emanuel Tenório , Silva-Júnior Edeíldo Ferreira , Júnior João Xavier Araújo , Ribeiro Êurica Adélia Nogueira
Published: March 2022

O tratamento farmacoterapêutico das síndromes metabólicas representam um desafio na farmacologia moderna, candidatos a fármacos para a síndrome metabólica recrutam atividades biológicas que induzam melhoras no eixo cardioendócrino, produzindo melhorias sobre a Hipertensão arterial sistêmica, Diabetes mellitus, dislipidemias, obesidade e/ou infarto agudo do miocárdio, atuando nos gaps´s de interconexão das patologias acima descritas. Não obstante os produtos finais da glicação avançada (AGES) engatilham o dano cardiovascular e endocrinológico e surgem como um alvo comum as doenças que compõe a síndrome metabólica. Os compostos anti-AGE´s aparecem como uma nova perspectiva na geração de candidatos a novos fármacos cardiometabólicos. Os promissores efeitos da aminoguanidina, estimularam a condução de estudos anti-AGE para o tratamento de doenças do eixo cardiometabólico. Assim, o objetivo deste trabalho foi realizar uma revisão dos novos protótipos de fármacos com o enfoque molecular em AGES como um alvo terapêutico relevante para compor o desenvolvimento de novos fármacos em farmacologia cardiometabólica. Os resultados revelaram que o desenvolvimento de protótipos de fármacos é desenvolvido para uma breve aplicação farmacológica. Em conclusão identificamos a existência das primeiras gerações de fármacos anti-AGE´s, baseadas nas técnicas de desenvolvimento da química medicinal e ainda a aplicação de compostos já disponíveis no mercado farmacêutico com ações anti-AGE, revelando seus avanços farmacoterapêuticos alicerçado no uso racional de fármacos.