bluuebunny/crossref_metadata_2025 huggingface dataset:
On some convergences to the constant e and improvements of Carleman’s inequality
Authors:   DEPARTMENT OF SCIENCE VALAHIA UNIVERSITY OF TARGOVISTE BD. UNIRII 18, 130082 TARGOVISTE, ROMANIA E-mail address: cristinel.mortici@hotmail.com, MORTICI CRISTINEL , YUE HU ,   HENAN POLYTECHNIC UNIVERSITY COLLEGE OF MATHEMATICS AND INFORMATICS JIAOZUO CITY, HENAN 454000, CHINA E-mail address: huu3y2@163.com
Published: April 2021

We present sharp inequalities related to the sequence (1 + 1/n)n and some applications to Kellers’ limit and Carleman’s inequality.
Some fixed point theorems via partial order relations without the monotone property
Authors:   DEPARTMENT OF MATHEMATICS, FACULTY OF SCIENCE NARESUAN UNIVERSITY PHITSANULOK, 65000, THAILAND E-mail address: w saksirikun@hotmail.co.th, SAKSIRIKUN WARUT , PETROT NARIN ,   DEPARTMENT OF MATHEMATICS, FACULTY OF SCIENCE NARESUAN UNIVERSITY PHITSANULOK, 65000, THAILAND E-mail address: narinp@nu.ac.th
Published: April 2021

The main aim of this paper is to consider some fixed point theorems via a partial order relation in complete metric spaces, when the considered mapping may not satisfy the monotonic properties. Furthermore, we also obtain some couple fixed point theorems, which can be viewed as an extension of a result that was presented in [V. Berinde, Generalized coupled fixed point theorems for mixed monotone mappings in partially ordered metric spaces, Nonlinear Anal., 74 (2011), 7347–7355].
A new approach to α-ψ-contractive mappings and generalized Ulam-Hyers stability, well-posedness and limit shadowing results
Authors:   DEPARTMENT OF MATHMATICS AND STATISTICS FACULTY OF SCIENCE AND TECHNOLOGY THAMMASAT UNIVERSITY RANGSIT CENTER PATHUMTHANI 12121, THAILAND. E-mail address: wutiphol@mathstat.sci.tu.ac.th, poom teun@hotmail.com, SINTUNAVARAT WUTIPHOL
Published: April 2021

In this paper, we introduce the new concept of weakly α-admissible mapping and give example to show that our concept is different from the concept corresponding existing in the literature. We also establish fixed point theorems by using such concept along with α-ψ-contractive condition and give some example which support our main result while previous results in literature are not applicable. Moreover, we study the generalized UlamHyers stability, the well-posedness and the limit shadowing for fixed point problems satisfy our conditions.
Plitidepsin, an inhibitor of the cell elongation factor eEF1a, and molnupiravir an analogue of the ribonucleoside cytidine, two new chemical compounds with intense activity against SARS-CoV-2
Authors: Reina Jordi ,   Unidad de Virología, Servicio de Microbiología, Hospital Universitario Son Espases, Facultad de Medicina (UIB). Palma de Mallorca. Spain
Published: April 2021

The knowledge of the replicative cycle of SARS-CoV-2 and its interactions with cellular proteins has opened a new therapeutic possibility based on blocking those essential for the virus. The cellular protein elongation factor eEF1A could be a good target. Among its natural inhibitors are didemnins and their related chemical compounds such as plitidepsin. In human cell culture, this compound is capable of inhibiting the virus with a potency 27,5 times that of remdesivir. It must be administered intravenously. Of the ribonucleoside analogues, molnupiravir (MK-4483/EIDD-2801) (hydroxy-cytidine) determines a lethal mutagenesis on SARS-CoV-2. In animals, after oral administration, the pulmonary viral load decreases 25,000 times and when administered as prophylaxis, approximately 100,000 times. It prevents the transmission of the virus and eliminates its presence in the oropharynx. Both chemicals have started Phase I / II human clinical trials
Some Implications of a Scale Invariant Model of Statistical Mechanics to Boltzmann versus Shannon Entropy in Thermodynamics and Information Theory
Authors: Sohrab Siavash H.
Published: April 2021

A scale invariant model of statistical mechanics is applied for a comparative study of Boltzmann’s entropy in thermodynamics versus Shannon’s entropy in information theory. The implications of the model to the objective versus subjective aspects of entropy as well as Nernst-Planck statement of the third law of thermodynamics are also discussed
Transformation of Values in the Context of National and Civilizational Rifts
Authors:   Medical University “Reaviz”, Шишкин А. Е.
Published: April 2021

The transformation of value meanings in Russia under the influence of the socio-political technologies of “consciental warfare” took place several times. The first turmoil occurred during the reign of Prince Vladimir through change of religion (from Vedism to Judeo-Christianity) and replacement of Glagolitic script by Cyrillic alphabet. The second unrest was organized in the period of the Seven Boyars; the third, during the October Revolution, while the fourth began under President Yeltsin’s rule and continues to the present day. Vasily Klyuchevsky believed that the essence of the turmoil lies in the national rifts between “soil” and “civilization”. According to Vladimir Solovyov, the struggle between clan and state relations is the main content of the history of Russia. The essence of civilizational rifts lies in the contradiction between globalization and localization in the conditions of cyclic stages of human development, especially pronounced in an era of change, when the clash of cultures intensifies. Nowadays, we have an understanding of how ersatz values are intentionally implanted with the help of soft power, but in order to resist national and civilizational entropy, we must create sociopolitical technologies that ensure consistent security. According to the author, a balance of power in a society can be established through restoring and preserving traditional community values. For Jean Monnet, the communal approach involves gathering the entire humanity into a single fraternal family (the mondialist project) to restrain the power of the market. The “communard methodology” of I.P. Ivanov and A.V. Mudrik considers the communal way of life as a “social phenomenon”, “part of culture” and “national heritage”. This paper suggests constructs for transforming society in the context of communitarianism, where people are authorized to create their own social reality. The new communitarian self-developing system, as an original solution for long-term development of Russia, should become an obstacle to national and civilizational rifts, manifested in social instability and colour revolutions.
INFLUENCE OF POPULATION NUMBER ON THE DEVELOPMENT OF THE INDUSTRY WITHIN THE FRAMEWORK OF AGLOMERATION
Authors: Павлов Юрий Владимирович
Published: April 2021

В статье с помощью матрицы расстояний выявляется вероятная численность населения в зоне возможного влияния территории, далее определяется способность к преодолению отраслью народного хозяйства порогового ограничителя по численности населения. В результате разработаны рекомендации по приоритету развития отраслей на территории.

In the article, using the distance matrix, the probable population size in the area of possible influence of the territory is revealed, then the ability of the industry to overcome the population threshold limit is determined. As a result, recommendations were developed on the priority of the development of industries in the territory.
DIGITAL TECHNOLOGIES ARE A FACTOR IN ACCELERATING ECONOMIC GROWTH
Authors: Андреев Олег Станиславович
Published: April 2021

В предложенной статье рассматривается роль цифровых технологий как фактора, влияющего на экономический рост не в меньшей степени, чем традиционные факторы - капитал и труд. В этой связи появились и расширяются исследования, связанные с феноменом «цифровые технологии»». Все это ставит перед любым государством задачу информатизации экономики, поскольку успешное ее решение становится одним из решающих условий роста конкурентоспособности страны. Основные мероприятия программных документов сводятся к приоритетному решению задачи информатизации макроуровня системы государственного управления экономикой. И в меньшей степени внимание уделяется аналогичным задачам на микроуровне экономики, к которому относятся, прежде всего, производственные предприятия, являющиеся главным звеном экономики.

The proposed article is concerned with the role of digital technologies as a factor influencing economic growth no less than traditional factors - capital and labor. In this regard emerged and expanded research related to the phenomenon of "digital technologies". All this poses the task of informatization of the economy for any state, since its successful solution becomes one of the decisive conditions for the growth of the country's competitiveness. The main activities of the program documents are resolved into the priority solution of the problem of informatization of the macro-level of the system of state management of the economy. And to a lesser extent, attention is paid to similar tasks at the microlevel of the economy, which include, first of all, manufacturing enterprises, which are the main link in the economy.
QUANTITATIVE ANALYSIS OF AGGLOMERATION EFFECTS IN SAMARA-TOGLIATTI'S Metropolitan area for FOOD INDUSTRY
Authors: Павлов Юрий Владимирович
Published: April 2021

Проведена количественная оценка двух составляющих агломерационного эффекта (эффектов урбанизации и локализации) на примере пищевой отрасли в рамках Самарско-Тольяттинской агломерации. Выявлено, что на производительность труда оказывают влияние численность населения в радиусе 120 км от центра муниципального образования и удалённость от Самары.

A quantitative assessment of two components of the agglomeration effect (the effects of urbanization and localization) was carried out using the example of the food industry within the Samara-Togliatti agglomeration. It was revealed that labor productivity is influenced by the population size within a radius of 120 km from the center of the municipality and the distance from Samara.
CURRENT CONTROL OF KNOWLEDGE IN MODERN CONDITIONS
Authors: Амиров Айрат Равилович
Published: April 2021

Рассматриваются вопросы практики применения автоматизированного контроля знаний студентов очной формы обучения. Отмечены основные преимущества и недостатки автоматизированного текущего контроля и возможные пути его совершенствования.

The article deals with the practice of using current control of knowledge of full-time students. The main advantages and disadvantages of automated monitoring and possible ways of its improvement are noted.
FEATURES OF MANAGEMENT OF THE EDUCATIONAL ORGANIZATION
Authors: Салаватова Асиль Магомедовна , Бойко Раиса Андреевна
Published: April 2021

В статье дается анализ современного состояния управления образовательной организации, раскрыты основные особенности управления образовательной организации. В статье структура управления образовательной организацией представлена пятью основными уровнями: уровень директора; педагогический совет, родительский комитет; уровень заместителей директора; уровень учителей; уровень учащихся.

The article analyzes the current state of management of an educational organization, reveals the main features of the management of an educational organization. In the article, the structure of management of an educational organization is represented by five main levels: director level; pedagogical council, parent committee; the level of deputy directors; the level of teachers; level of students.
ENSURING TECHNOSPHERIC SAFETY OF ELECTROCHEMICAL PRODUCTION
Authors: Виноградов Олег Станиславович , Виноградова Наталья Александровна , Барановская Ольга Владимировна , Яловой Алексей Евгеньевич
Published: April 2021

В статье описана возможность перехода предприятий электрохимического профиля на систему экономии воды и материалов, а также снижения экологической нагрузки на окружающую среду.

The article describes the possibility of transition of enterprises of an electrochemical profile to a system of saving water and materials, as well as reducing the environmental load on the environment.
OBSERVATIONS OVER REGIONAL WORDS IN THE POETRY OF V. V. PORTUGALOV
Authors: Пальчикова Дарья Дмитриевна , Семенов Алексей Иванович
Published: April 2021

В статье рассматриваются типы регионализмов, особенности их функционирования в произведениях В. В. Португалова. Многие анализируемые слова принадлежат к группе относительных регионализмов, это связано с тем, что интересующие нас произведения ориентированы на носителей литературного языка - читателей, проживающих в различных районах России.

The article examines the types of regionalisms, the peculiarities of their functioning in the works of V.V. Portugalov. Many of the analyzed words belong to the group of relative regionalisms, this is due to the fact that the works of interest to us are focused on native speakers of the literary language - readers living in different regions of Russia.
USING THE WIX WEB SERVICE FOR CREATING AN ONLINE QUIZ IN EDUCATION
Authors: Демичева Татьяна Дмитриевна , Преминина Яна Клавдиевна
Published: April 2021

В статье рассмотрены особенности использования веб-сервиса Wix для создания онлайн - викторины в образовательном процессе.

The article discusses the features of using the Wix web service to create an online quiz in the educational process.
MEDIA TEXT AS A BASIC CATEGORY OF MEDIA LINGUISTICS: PROBLEMS OF IDENTIFICATION, DELIMITATION, AND TYPOLOGY
Authors: Мякшин Кирилл Александрович
Published: April 2021

Статья посвящена исследованию медиатекста в контексте многообразия научных подходов. Определены основные концепты, в которых себя представляет феномен данного текста. Предпринята попытка определить основные контексты существования медиатекстов, что позволяет выделить социально-культурное поле бытия медиатекста, установить его социально-историческую обусловленность. Рассмотрена типология указанного вида текста.

The article deals with the study of media text in the context of a variety of scientific approaches. The main concepts in which the phenomenon of this text represents itself are defined. An attempt is made to determine the primary contexts of the existence of media texts, which allows identifying the socio-cultural field of the existence of the media text, establishing its socio-historical conditionality. The typology of this type of text is considered.
ENSURING TECHNOSPHERE SAFETY AT THE STAGE OF EQUIPMENT DESIGN
Authors: Виноградов Олег Станиславович , Виноградова Наталья Александровна , Барановская Ольга Владимировна , Лопатина Анастасия Юрьевна
Published: April 2021

В статье приведено описание программных продуктов для расчетов по обеспечению устойчивой работы оборудования и обеспечения факторов безопасности и экологической чистоты производственных процессов.

The article contains a description of software products for calculations to ensure the stable operation of equipment and ensure safety factors and environmental cleanliness of production processes.
Modellbasierte Berechnung des aerosolgebundenen Infektionsrisikos in Klassenräumen, Großraumbüros, Hörsälen und Sporthallen bei unterschiedlichen Nutzungssituationen/Model-based calculation of the aerosol-related risk of infection in classrooms, open-plan offices, lecture halls and sports halls for different usage situations
Authors: Schweiker Marcel , Salthammer Tunga , Moriske Heinz-Jörn , Tappler Peter , Scherer Christian , Trukenmüller Alfred , Müller Dirk
Published: April 2021

In diesem Beitrag werden Ergebnisse eines Berechnungsverfahrens zur Bewertung eines relativen Infektionsrisikos vorgestellt, mit dem eine (beliebige) Raumsituation mit einer Referenzsituation verglichen werden kann. Die Referenzsituation beschreibt einen Klassenraum mit maschineller Belüftung, ausgelegt nach dem heutigen Stand der Technik. Dabei wird vorausgesetzt, dass keine absolute Sicherheit vorliegt, jedoch eine nur sehr geringe Infektionswahrscheinlichkeit angenommen wird. Durch die Wahl der Raum- und Lüftungsparameter wird sichergestellt, dass sich in der Referenzsituation nach dem heutigen Stand des Wissens Infektionen über virentragende Aerosolpartikel nur beschränkt bis gar nicht ausbreiten können. Für Fälle, in denen keine Ausstattung mit meist zentral gesteuerten raumlufttechnischen Anlagen (RLT-Anlagen) vorliegt, was für die meisten Schulen gilt, wurde in Schulklassenräumen mit Lüftung über Fenster ebenfalls eine Referenzsituation mit einem relativen Infektionsrisiko von „1“ beschrieben und als Berechnungsbezug verwendet. Alle Berechnungen können sowohl stationär als auch instationär über eine Internetseite für eigene Räume und Szenarien durchgeführt werden (http://risico.eonerc.rwth-aachen.de/). Bei allen modellbasierten Betrachtungen bleiben andere Übertragungswege, wie Kontaktübertragung, das Nicht-Beachten allgemeiner Hygieneregeln oder direkte Kontakte, unberücksichtigt. Auch das generelle Tragen von besonders wirksamen Mund-Nasen-Bedeckungen (MNB) wie FFP2- oder OP-Masken mit CE-Zeichen nach DIN EN 14683, wie es sich in der politischen Diskussion zunehmend als Vorgabe abzeichnet, wird nicht vorausgesetzt.
Book Review: Foundations of Artificial Intelligence in Healthcare and Bioscience
Authors: Freeman Paul B.
Published: April 2021

Book Review:

Catania LJ. Foundations of Artificial Intelligence in Healthcare and Bioscience. Cambridge: Academic Press; 2020, $150.00, 524 pages, Paperback ISBN:9780128244777, e-book ISBN: 9780323860055.
Functions of legal guarantees in labor law: current issues
Authors: Pyzhova Maryna Pyzhova
Published: April 2021

Problem setting. The concept of “guarantee” is the subject of many scientific studies, and in various fields of law. But this is especially true of labor law, and above all, work on guarantees of labor rights of citizens. That is why a special place in the system of national labor law is occupied by the institution of guarantees and compensations. Unfortunately, the outdated Labor Code of Ukraine has significant problems with terminological uncertainty, as it contains neither a definition of guarantees nor a definition of compensation, in contrast to the Labor Code of the Russian Federation, where Article 164 clearly defines that guarantees are funds. ways and conditions by which the exercise of rights granted to employees in the field of social and labor relations is ensured. And compensations are monetary payments established for the purpose of reimbursement to employees of the expenses connected with performance by them of labor or other duties provided by this Code and other federal laws. Therefore, we see it necessary to investigate and determine the purpose and indicate what functions are guaranteed by labor law in Ukraine.
Analysis of recent research. Scientists approach the understanding of the essence and content of legal guarantees in different ways, among them E. Ametistov, V. Andriev, N. Bolotina, O. Valetska, S. Venediktov, S. Verlanov, M. Grekova, S. Ivanov, I. Kiselyov, N. Kokhan, E. Krasnov, M. Feskov, G. Chanisheva, and problems of the institute of remuneration – V. Bozhko, V. Zhernakov, M. Inshin, O. Protsevsky, S. Prilipko, O. Sytnitskaya, N. Khutoryan, O. Yaroshenko, I. Yatskevich and others.
Target of research is to consider the issue of legal guarantees in labor law and highlight their functions.
Article’s main body. The article considers the issue of assigning legal guarantees in labor law. The author’s definition of the functions of legal guarantees in labor law is given, it is indicated that these are the areas of influence on the realization of employees and employers of their labor rights and responsibilities, protection of rights and freedoms and their restoration in case of violation. It is proposed to distinguish four main functions of legal guarantees in labor law, including security, instrumental, creating a balance between the interests of the employee and the employer, providing stability to labor relations. The articles of the national security legislation which express the specified functions are analyzed.
Conclusions and prospects for the development. In our opinion, the definition and understanding of the functions of legal guarantees in labor law is necessary for further scientific and theoretical study of the institution of guarantees in labor law, as well as for law enforcement. We are convinced that guarantees are an important and necessary tool for the realization of the declared rights and freedoms of citizens in the field of labor. That is why there is an urgent need to develop and consolidate at the legislative level the conceptual apparatus of the institution of guarantees.
The European ombudsman as a body for the protection of the rights of individuals and legal entities in the European Union
Authors: Maryniv Ivanna , Kotenko Andriy
Published: April 2021

Formulation of the problem. Today, the EU faces new challenges due to the globalization policy pursued by most EU member states, migration and the global pandemic - COVID-19. In the new conditions, the protection of human rights acquires a fundamentally new meaning. Therefore, the question of the role of the EU Ombudsman in the process of protection of individual rights and control over the activities of bodies is very relevant.
By choosing the path of European integration and committing itself under the Association Agreement to adapt a number of areas in line with the acquis communautaire, Ukraine should also focus on the experience of the European Ombudsman. Since taking office as the Ukrainian Parliamentary Commissioner for Human Rights in 1998, it will not be an exaggeration to state that there are a number of problems in overseeing the proper activities of the authorities in respecting human and civil rights and freedoms. That is why, given the shortcomings and the chosen vector of development, the experience of the European Ombudsman is of great importance for Ukraine in order to improve the activities of the Ukrainian Parliament’s Commissioner for Human Rights.
Target of research is to examine the role of the EU Ombudsman in the process of investigating good governance in the EU institutional mechanism.
Article’s main body. The article is devoted to the study of the legal status of the European Ombudsman as a body that must investigate improper bodies of the activities of institutions, agencies to ensure the restoration of violated rights guaranteed by the Charter of Fundamental Rights of the European Union. The analysis of the practice of the European Ombudsman in the official annual reports, as well as the development strategy is carried out. With the help of EU legislation research and conducting of the legal analysis of the Ombudsman’s annual reports, strategic development documents and enquiries, opened by the Ombudsman in the last decade, the complexity of the European ombudsman’s contribution to the implementation of the sustainable development principle within EU’s supranational legal framework.
Conclusions. After analyzing the development of Ombudsman’s legal status and the results of his enquiries, conducted in the last decade, a conclusion has been made, that the European ombudsman considerably influences all the institutional system of the EU. His initiatives have far-reaching consequences which might have caused their effect on the whole legal framework of the EU, in case if the European ombudsman had been given some more legal powers. Though, having only recommendation mechanisms in possession, this body influences the governing system of the EU largely, causing positive changes, meeting the leading principles of the functioning of the EU.
The hybrid firefly algorithm with the fuzzy movement method for solving a complex scheduling problem
Authors: Phu-ang Ajchara
Published: April 2021

This paper proposes a hybrid algorithm that applied the firefly algorithm (FA) with the new idea labeled as the fuzzy movement method for solving a complex scheduling problem called the flexible job shop scheduling. The step of the proposed algorithm is similar to the original FA, which is based on the concept of flashing behavior to attract the other fireflies. In order to improve the efficiency of the FA algorithm for the FJSP, the proposed algorithm introduces three new ideas. In the first idea, the genetic algorithm (GA) is used to generate the high quality of the initial population. Next, the self-adaptive roulette wheel selection which embedded in the GA introduced to increase the diversity of the machine selection process. Finally, the fuzzy movement method is presented to enhance the work balancing ability between the high workload machines and the low workload machines. The proposed algorithm has been evaluated with a benchmark data set and compared to the other algorithm. The experimental results demonstrate that the proposed algorithm can effectively solve the flexible job shop scheduling problem.
Front Line Nurse Managers’ Attitudes And Perceived Barriers Towards Continuous Education In Nursing; Sri Lanka
Authors: Jayamaha Akila R , Kanchana K. T. G. , Perera A. C. H. , Nisansala M. W. N. , Priyadarshani U. G. N. , Sewwandi K. P. A. , Dharmarathna H. H. N. D. , Senerath N. S. A. S. N. , Nawarathne L. C. , Sepalika H. M. S. , Karunawasala U. , Samanmali M. B. C.
Published: April 2021

Abstract

Continuous education is a vital factor which contributes towards the professional development in nursing and it is directly associated with the health of a country. Continuous education is essential to maintain and improve the knowledge, skills, and attitudes of nurses and provide better health care. The objective of this study was to assess the attitudes and perceived barriers towards continuous education in nursing among the front-line nurse managers in Sri Lanka. A descriptive cross-sectional study was conducted among 555 front line nurse managers in Sri Lanka using a self-administered questionnaire. Data analysis was done using descriptive statistics. SPSS 25 version was used as the data analysis tool. Thirty-one special grade nursing officers and 524 grade 1 nursing officers participated in this study. The majority (73%) had more than 20 years of working experience as a nursing professional. Most of the nurse
managers were diploma holders (83%), 3% undergraduates, 14% graduates, and 1% were reading for Masters. Attitudes towards continuous education were good among all the nurse managers, while 92% were willing to continue their education. The majority (96%) has perceived that continuous education is vital for professional development in nursing, and 91% has stated that the opportunities and facilities for continuous education and nursing research should be improved. The attitudes borne by the front line nurse managers towards continuous education, were considered to have been very positive. Further, continuous education was perceived by them as a vital part of professional development. Therefore, it could be surmised that the opportunities and facilities for continuous education and research on continuous nursing education should be improved in order to facilitate the provision of better health care.

Keywords: Continuous Education, Nurse Managers, Attitudes
ORTADOĞU’DA SİVİL İTAATSİZLİK EYLEMLERİ; 1979 İRAN DEVRİMİ ÜZERİNE BİR İNCELEME
Authors: ONUTÇU ALKIŞ Asya
Published: April 2021

1979 İran devrimi, modern dönemde Ortadoğu’da gerçekleşmiştir. Hala devrim ile yönetime gelenlerin İran’da yönetiminde mevcudiyetini koruması ve devrimin gerçekleştiği dönemde kimsenin İran’da bir devrimin gerçekleşeceğini öngörememesi devrimi önemli kılmaktadır. Bundan dolayı 1979 İran Devrimi modern dönemin en şaşırtıcı devrimlerinden biri olarak yorumlanmıştır. Modern dönemin bu ilgi çeken devrimi ve devrime giden süreçte yaşanan eylemlerin sivil itaatsizlik bakışıyla, sivil itaatsizliğin unsurları açısından incelenmesi çalışmamızın konusunu oluşturmuştur. Eylemler incelenirken özellikle sivil itaatsizliğin dar tanımı esas alınmıştır.
Clinical Characteristics, Management, and Potential Biomarkers of Endocrine Dysfunction Induced by Immune Checkpoint Inhibitors
Authors: Iwama Shintaro , Kobayashi Tomoko , Arima Hiroshi
Published: April 2021

Immune-related adverse events (irAEs) affecting the endocrine glands are among the most frequent irAEs induced by immune checkpoint inhibitors (ICIs) and include hypopituitarism, primary adrenal insufficiency, thyrotoxicosis, hypothyroidism, hypoparathyroidism, and type 1 diabetes mellitus. Since the incidence and clinical features of endocrine irAEs vary according to the ICI used, it is important to understand the characteristics of these irAEs and to manage each one appropriately. Since some endocrine irAEs, including adrenal crisis and diabetic ketoacidosis, are potentially life-threatening, predicting the risk of endocrine irAEs before their onset is critical. Several autoantibodies have been detected in patients who develop endocrine irAEs, among which anti-thyroid antibodies may be predictive biomarkers of thyroid dysfunction. In this review, we describe the clinical features of each endocrine irAE induced by ICIs and discuss their potential biomarkers, including autoantibodies.
The role of neutrophil/lymphocyte ratio and mean platelet volume in diagnosis of ovarian torsion
Authors: ÖKSÜZOĞLU Ayşegül
Published: April 2021

Aim

Ovarian torsion is one of the gynecological emergencies that often presents with non-specific symptoms leading to delayed diagnosis. There are no adequate clinical, laboratory or imaging criteria to make a definitive diagnosis of ovarian torsion preoperatively. The aim of this study was to investigate the role of the neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) value in the diagnosis of patients with ovarian torsion.

Materials and method

A total of 198 women were included in this retrospective study and two study groups were formed. Group 1 consisted of 66 patients diagnosed with ovarian torsion following abdominal exploration and the control group consisted of 132 patients who were operated for benign unruptured ovarian cysts (Group 2). Groups were compared according to clinical characteristics and hematological parameters. Demographic and clinical characteristics and preoperative complete blood count parameters were retrieved from the medical records. Results: Mean leukocyte, neutrophil, and NLR were significantly higher, and MPV was significantly lower in patients with ovarian torsion compared to controls (p
Evlilikte Eşe Yönelik Gerçekleşen Cinsel Saldırı: Eş Tecavüzü
Authors: TÜLÜ İsmail Altan , ÜSTÜN GÜLLÜ Belgin , MORALOĞLU TEKİN Özlem
Published: April 2021

Cinsel saldırı, saldırıda bulunan kişinin mağdura yakınlığı bakımından, mağdurun tanımadığı bir kişi tarafından gerçekleşen cinsel saldırı; bir buluşma sonrası mağdurun yeni tanıdığı bir kişi tarafından gerçekleşen cinsel saldırı ve mağdurun eşi veya beraber yaşadığı partneri tarafından gerçekleşen cinsel saldırı olmak üzere üç şekilde gerçekleşmektedir. 1970’lerden sonra yasal zeminde ilk kez konuşulmaya başlayan evlilik içi cinsel saldırının, eşin rızası olmadan, zorlama, baskı ve güç kullanılarak, öfke, güç ve sadistik duyguları tatmin etmek amacıyla gerçekleştirildiği ifade edilmektedir. Saldırıyı gerçekleştirenlerin çoğunda, iletişim becerilerinde yetersizlik ve karşı cinse yönelik duygusal yakınlık kurmada problemlerin yaşandığı; mağdurların çoğunda ise, saldırı sonrası bir takım psikolojik, fizyolojik ve jinekolojik problemlerin ortaya çıktığı belirtilmektedir. Yaşanılan problemlerin tedavisine yönelik olarak, uygun tedavi seçenekleri de bulunmaktadır. Ülkemize ait geleneksel değerler, kadına yönelik sosyo-kültürel bakış açısı, ailenin ve özel ilişkilerin mahremiyeti gibi konular nedeniyle evlilik içi gerçekleşen cinsel saldırının çok fazla açığa çıkarılmadığı düşünülmektedir. Bu çalışmada, evlilik içi eşe yönelik olarak gerçekleştirilen cinsel saldırının özetlenmesi amaçlanmıştır.
AN ANALYTIC NETWORK PROCESS BASED RISK ASSESSMENT MODEL FOR PPP HYDROPOWER INVESTMENTS
Authors: Akcay Emre Caner
Published: April 2021

The number of public-private partnership (PPP) projects has gone up especially in developing countries. The risk assessment of PPP projects is essential in ensuring project success. The objective of this study is to develop an Analytic Network Process (ANP) based risk assessment model for hydropower investments, and a tool to facilitate quantification of risk ratings based on this model. The results show that the three most important risk factors that affect the overall risk rating of a PPP hydropower investment are legal risks, contractor/subcontractor risks, and operator risks. In addition, the three most important risk clusters were identified as stakeholders, government requirements, and resources, whereas market was the least important cluster. The tool that measures the risk rating of a PPP of hydropower project was tested on ten real cases, and satisfactory results were obtained in terms of its predictive capability. The contributions of this research include (1) identification of the risk factors and clusters of factors associated with PPP hydropower investments; (2) determination of the priority of each risk factor and cluster; (3) development a tool that guides the investors through the risk assessment of PPP hydropower investments.
Projected Rotational Velocities and Fundamental Properties of Low-mass Pre-main-sequence Stars in the Taurus–Auriga Star-forming Region
Authors: Nofi Larissa A. , Johns–Krull Christopher M. , López–Valdivia Ricardo , Biddle Lauren , Carvalho Adolfo S. , Huber Daniel , Jaffe Daniel , Llama Joe , Mace Gregory , Prato Lisa , Skiff Brian , Sokal Kimberly R. , Sullivan Kendall , Tayar Jamie
Published: April 2021

The projected stellar rotational velocity (

) is critical for our understanding of processes related to the evolution of angular momentum in pre-main-sequence stars. We present

measurements of high-resolution infrared and optical spectroscopy for 70 pre-main-sequence stars in the Taurus–Auriga star-forming region, in addition to effective temperatures measured from line-depth ratios, as well as stellar rotation periods determined from optical photometry. From the literature, we identified the stars in our sample that show evidence of residing in circumstellar disks or multiple systems. The comparison of infrared

measurements calculated using two techniques shows a residual scatter of ∼1.8 km s−1, defining a typical error floor for the

of pre-main-sequence stars from infrared spectra. A comparison of the

distributions of stars with and without companions shows that binaries/multiples typically have a higher measured

, which may be caused by contamination by companion lines, shorter disk lifetimes in binary systems, or tidal interactions in hierarchical triples. A comparison of optical and infrared

values shows no significant difference regardless of whether the star has a disk or not, indicating that CO contamination from the disk does not impact

measurements above the typical ∼1.8 km s−1 error floor of our measurements. Finally, we observe a lack of a correlation between the

, presence of a disk, and H-R diagram position, which indicates a complex interplay between stellar rotation and evolution of pre-main-sequence stars.
Orbital Evolution of Binary Black Holes in Active Galactic Nucleus Disks: A Disk Channel for Binary Black Hole Mergers?
Authors: Li Ya-Ping , Dempsey Adam M. , Li Shengtai , Li Hui , Li Jiaru
Published: April 2021

We perform a series of high-resolution 2D hydrodynamical simulations of equal-mass binary black holes (BBHs) embedded in active galactic nucleus (AGN) accretion disks to study whether these binaries can be driven to merger by the surrounding gas. We find that the gravitational softening adopted for the BBH has a profound impact on this result. When the softening is less than 10% of the binary separation, we show that, in agreement with recent simulations of isolated equal-mass binaries, prograde BBHs expand in time rather than contract. Eventually, however, the binary separation becomes large enough that the tidal force of the central AGN disrupts them. Only when the softening is relatively large do we find that prograde BBHs harden. We determine through detailed analysis of the binary torque, that this dichotomy is due to a loss of spiral structure in the circum-single disks orbiting each black hole when the softening is a significant fraction of the binary separation. Properly resolving these spirals—both with high resolution and small softening—results in a significant source of binary angular momentum. Only for retrograde BBHs do we find consistent hardening, regardless of softening, as these BBHs lack the important spiral structure in their circum-single disks. This suggests that the gas-driven inspiral of retrograde binaries can produce a population of compact BBHs in the gravitational-wave-emitting regime in AGN disks, which may contribute a large fraction to the observed BBH mergers.
Construction of Explicit Symplectic Integrators in General Relativity. III. Reissner–Nordström-(anti)-de Sitter Black Holes
Authors: Wang Ying , Sun Wei , Liu Fuyao , Wu Xin
Published: April 2021

We give a possible splitting method to a Hamiltonian for the description of charged particles moving around the Reissner–Nordström-(anti)-de Sitter black hole with an external magnetic field. This Hamiltonian can be separated into six analytical solvable pieces, whose solutions are explicit functions of proper time. In this case, second- and fourth-order explicit symplectic integrators are easily available. They exhibit excellent long-term behavior in maintaining the boundness of Hamiltonian errors regardless of ordered or chaotic orbits if appropriate step sizes are chosen. Under some circumstances, an increase of the positive cosmological constant gives rise to strengthening the extent of chaos from the global phase space; namely, chaos of charged particles occurs easily for the accelerated expansion of the universe. However, an increase of the magnitude of the negative cosmological constant does not. The different contributions to chaos are because the cosmological constant acts as a repulsive force in the Reissner–Nordström-de Sitter black hole, but an attractive force in the Reissner–Nordström-anti-de Sitter black hole.
Labiobaetis Novikova & Kluge in West Africa (Ephemeroptera, Baetidae), with description of a new species
Authors: Kaltenbach Thomas , Gattolliat Jean-Luc
Published: April 2021

Material collected between 1984 and 1988 in Guinea and Mali and between 2003 and 2008 in the Ivory Coast substantially increased our knowledge of Labiobaetis Novikova & Kluge in West Africa. We identified eight different species using morphological characters. One species, L. ediaisp. nov., is new to science; it is described and illustrated, based on its nymphs. The status of L. boussoulius (Gillies, 1993) is discussed and the divergent morphology of L. elouardi (Gillies, 1993) is compared to other species of Labiobaetis. A key to the nymphs of all West African species is provided and the distribution of Labiobaetis species in the Afrotropical realm is discussed.
Species conservation profile and amended distribution of Cousinia knorringiae (Asteraceae), a narrow endemic of the Western Tian-Shan
Authors: Usmonov Mansur , Tojibaev Komiljon , Jang Chang-Gee , Sennikov Alexander
Published: April 2021

Cousinia knorringiae Bornm. (Asteraceae) belongs to C. sect. Subappendiculatae Tscherneva, a group of the species-rich and taxonomically difficult genus Cousinia Cass. This species is narrowly distributed in the Western Tian-Shan and has been known as endemic to Kyrgyzstan. It inhabits bare rocks and screes at elevations of 1200–1500 m above sea level. This species is of conservation interest because of its small population size and limited distribution.

Cousinia knorringiae is reported for the first time from eastern Uzbekistan on the basis of specimens collected on Ungur-Tepa Mt., a south-western outlier of the Bozbu-Too Mts. (Western Tian-Shan). The conservation status of the species is assessed as Endangered (EN), based on criterion D (estimated population size 200-250 mature individuals), according to the IUCN Red List Categories and Criteria (version 3.1). A new distribution map and a line drawing for C. knorringiae are provided and its type locality is clarified. The new knowledge suggests that the species is endemic to the East Fergana botanical hotspot, which includes a transborder territory shared between Kyrgyzstan and Uzbekistan and should, therefore, be subjected to international conservation measures. The southern extension of Ungur-Tepa Mt. harbours important plant species, which cannot be found elsewhere in Uzbekistan and may, therefore, be proposed for legal protection.
Potential changes in the distribution of Delphinium bolosii and related taxa of the series Fissa from the Iberian Peninsula under future climate change scenarios
Authors: Ramírez-Rodríguez Rubén , Melendo-Luque Manuel , Rus-Moreno Juan Diego , Amich Francisco
Published: April 2021

A particular threat posed by climate change for biodiversity conservation, one which has scarcely been studied, is the overlap of the potential distribution areas in phylogenetically closely related species. In this study, Species Distribution Modelling (SDM) was used to investigate the potential changes in the distribution of Delphinium bolosii and D. fissum subsp. sordidum under future climatic scenarios. These two closely related and endangered endemic species from the Iberian Peninsula do not have complete reproductive barriers between them. The two models selected different predictors with a similar effect in the biological cycle. Both taxa need low winter temperatures to break seed dormancy and sufficient rainfall to complete the flowering and fruiting stages. The current potential distribution areas of both taxa do not currently overlap. However, the results showed that potential changes may take place in the species’ distribution range under future climate scenarios. The models predict a reduction of the potential distribution area of D. bolosii while, conversely, the potential distribution area of D. fissum subsp. sordidum increased. In both cases, the predicted contraction in range is very high, and loss of habitat suitability in some current localities is worrying. Notwithstanding, the models do not predict overlaps of potential areas under climate change scenarios. Our findings can be used to define areas and populations of high priority for conservation or to take action against the impacts of climate change on these endangered species.
Tigriopus iranicus sp. nov., a new species of Harpacticidae (Copepoda, Crustacea) from Iran, with a redescription of T. raki Bradford, 1967
Authors: Nazari Fatemeh , Mirshamsi Omid , Martínez Arbizu Pedro
Published: April 2021

The first representative of Tigriopus Norman, 1869 from the north-western Indian Ocean is described from rock pools on the Iranian coast. Tigriopus iranicussp. nov. is distinguishable from its congeners by i) the possession of two maxillary endites, each with two setae; ii) a two-segmented mandibular endopod; iii) P1enp-3 with one pinnate claw, a well-developed geniculate spine and a small seta; and iv) female P6 with two setae. Additionally, we present a complete redescription of Tigriopus raki Bradford, 1967 on the basis of paratype material and a key to the species of the genus.
Punk comme un porc
Authors: Rosenthal Rob , Quément Fanny
Published: April 2021

Membre fondateur des Freeze, groupe de punk du Cap Cod, dans le Massachussetts, né en 1978 et connu pour sa longévité, Robert Rosenthal a quitté le navire en 1982. Il enseigne aujourd’hui le journalisme radiophonique. Dans un épisode de Lost Notes , série de podcasts lancée par Jessica Hopper pour KCRW, il revient sur son passé punk pour évoquer un sentiment de honte enfoui en lui depuis cette époque. Une honte liée à une certaine chanson de Freeze, « I Hate Tourists », premier single et premier succès du groupe. Le récit se construit donc dans la confrontation des points de vue afin d’aborder des questions de responsabilité, de transmission et de rapport au passé. Rosenthal se devait d’aborder le sujet, avec sa propre fille comme avec cet ami d’enfance qui joue encore dans le groupe, Clif « Hanger » Croce, et qu’il n’avait pas revu depuis des années. Alors, que faire de « I Hate Tourists » ? Rosenthal ne se défile pas. La réponse qui se dessine à l’horizon de son récit apporte un éclairage essentiel dans les débats en cours sur la « cancel culture ». Le texte que nous vous proposons de lire est une adaptation française de ce podcast. Il prend, lui aussi, la forme d’une histoire plutôt que celle d’un article.
Garanties de l’autonomie patrimoniale des jeunes Églises en République démocratique du Congo
Authors: Mole Mogolo Gratien
Published: April 2021

Plusieurs facteurs font obstacle à l’autonomie patrimoniale des jeunes Églises en République démocratique du Congo. Ils ont été identifiés, entre autres, par le cardinal Malula. Des propositions qui visent la croissance de cette autonomie ont été faites par le pape Jean-Paul II et par différentes assemblées supra-épiscopales africaines. D’un point de vue canonique, des solutions institutionnelles et l’inculturation du droit par la création d’un droit particulier pourraient également y contribuer.
Mgr Costantini, premier délégué apostolique, responsable canonique des missions catholiques de Chine (1922-1932)
Authors: Wang Jiyou Paul
Published: April 2021

Prenant appui sur les sources conciliaires et législatives, l’auteur retrace ici la convocation et le déroulement du premier concile plénier de Chine. Celui-ci fut organisé en 1924 sous l’impulsion du délégué apostolique, Mgr Celso Costantini. L’article rend compte des problèmes politiques et des difficultés canoniques dont souffraient alors les missions de Chine. Il examine l’attitude des missionnaires étrangers à l’égard de la culture et des traditions chinoises, et au regard des lois canoniques particulières concernant les diverses catégories de fidèles catholiques : missionnaires, clercs et laïcs autochtones. Il montre, enfin, comment ce premier concile a renforcé l’implantation du christianisme dans la société chinoise moderne et a marqué une étape capitale vers la naissance d’une Église locale catholique authentiquement chinoise.
Les facteurs de satisfaction liés à l’environnement de travail des managers transfrontaliers du Rhin supérieur
Authors: Wodociag Sophie
Published: April 2021

Alors que le recours à la main d’œuvre transfrontalière connaît une forte croissance (> 21% entre 1999 et 2012 dans le Rhin Supérieur (Insee, 2016)), la relation à l’emploi des transfrontaliers reste peu étudiée. Pourtant, la pénibilité des conditions de travail (Garufo, 2014), induite par la fatigue liée aux trajets quotidiens alliée à un rythme de travail élevé (DeFranck et al. , 2000) en questionne la pérennité. L’examen conceptuel des exigences et ressources de travail (Bakker et Demerouti, 2007) sur la satisfaction (Larouche et al. , 1973) des transfrontaliers apporte de premiers éléments de réponse descriptifs. Une étude qualitative réalisée auprès de 29 managers transfrontaliers du Rhin Supérieur permet d’approfondir la compréhension du processus. Elle met principalement en évidence la perception d’une reconnaissance liée à la rémunération, aux possibilités d’évolution professionnelle et à l’exercice d’une responsabilité hiérarchique.
L’Europe, contrainte ou renfort ?
Authors: Benlolo-Carabot Myriam
Published: April 2021

Le sentiment d’une érosion inexorable des pouvoirs de l’État face à l’Union européenne est désormais largement répandu. Il repose sur des éléments divers qui tendent à présenter le droit de l’Union comme un ensemble monolithique, mis en œuvre par un pouvoir centralisé habilité à imposer la norme européenne, y compris dans le champ des compétences régaliennes de l’État. De telles assertions négligent la complexité et la spécificité de la contrainte européenne, laquelle diffère en fonction notamment des caractéristiques et du processus d’élaboration de l’acte adopté, de la nature de la compétence attribuée à l’Union ou de l’étendue des dérogations accordées aux États. Finalement, ce sont les termes du débat lui-même, en particulier la notion de « souveraineté », qui sont redéfinis, l’État trouvant dans l’Union un cadre renouvelé d’exercice de ses pouvoirs.