bluuebunny/crossref_metadata_2025 huggingface dataset:
Estenose Ureteropélvico Fetal – Diagnosticada pela Ultra-sonografia
Authors: Bastos Guilherme de Almeida , Laurino Danilo Micheletto , Kashiwabuch Marcelo Kazuo , Agostini Pedro Adri Oliveira , Ploch Rafael de Souza Ramos
Published: October 2021

Os Autores relatam um caso de estenose na Junção Uretero-Pélvico à esquerda, diagnosticado no pré-natal pela ultra-sonografia com 25 semanas de gestação. A importância do diagnóstico precoce foi a interrupção da gestação antes de ocorrer uma perda renal fetal ou lesão irreversível renal do Recém-nascido (RN).
Pengaruh Manajemen terhadap Mutu Pendidikan Sekolah
Authors: Srihartini Yusi
Published: October 2021

This research was conducted with the aim of seeking information that there was an influence of management on improving the quality of school education, based on the Education Unit Level Curriculum or abbreviated as the KTSP in 2006. The study was conducted on elementary level education staff (SD / MI and SMP / MTS) and intermediate (SMA / MA and SMK / MAK) who have implemented the curriculum, especially the Jakarta area.

The results of the study for the group of education workers who implemented KTSP management had an average of 6.97 and for the group of educators who did not implement the KTSP obtained Lₒ of 0.1204 and for the group of educators not implementing KTSP management it was obtained at 0.1268 while L table for 40educators, a significant level of 0.05 at 0.14 means lₒ <Ltabel. It can be concluded that the population has a normal distribution. The results of the homogeneity research obtained X counts of 0.0053 X² table of 3.84 means that X² counts <x² tables, it can be concluded that both populations have the same variance or homogeneity. Testing the hypothesis by using the t test obtained t count of 2.1483 while the significant level of 0.05 degrees of freedom 78 obtained t table of 1.66 means t count> t table then Hᵃ is accepted so that there is management influence on the quality of school education for educational units implementthe KTSP.
Pengaruh Pergeraka Tingkat Suku Bunga dan Inflasi terhadap Nilai Aktiva Bersih Reksadana Saham
Authors: Evinovita Evinovita , Rahim Anwar , Ishardyatmo Handono
Published: October 2021

This study aims at determining the influence of BI interest rate  and inflation toward NAV balance mutual funds. This research was conducted during the period of data since 2008 to 2012. The sample used was the 30 balance mutual funds that are registered and active traded in Bapepam. From the results of the research literature conclude the basic assumptions that variable BI interest rate, and inflation levels affect the NAV of balance   mutual funds. Hypothetical tested is that there is a significant influence among independent variables to dependent variables, both partial and simultaneous. Research was conducted with regression analysis using application of Eviews 6.0. The test results shows that thypothetical is supported by data. Variable index BI interest rate    can  influence a positive significant to NAV  balance mutual  funds amounted   2,152514; inflastion levels can influence a negative significant to NAV balance mutual funds amounted  0,730341; the independent variables BI rate (X1) and inflastion (X2) both partial and simultaneous can influence to NAV balance mutual funds

at trust level 5%.
Pengaruh Reward dan Punishment terhadap Motivasi Kerja Karyawan di PT Antam Tbk UBPE Pongkor Departemen Process Plant
Authors: Badrudin Dudu , Hadi Sholikul , Supriyatna Rio Kartika
Published: October 2021

ABSTRACT

Employee work motivation must always be maintained and improved, one way is by implementing rewards and punishments. To improve effective performance, organizational agencies can pay attention to the most important thing, namely meeting the needs of their employees. The objectives of this study include (1) to analyze the effect of reward on employee work motivation (2) to analyze the effect of punishment on work motivation (3) to analyze the effect of reward and punishment on employee motivation at PT Antam Tbk, UBPE Pongkor. The method used in this research is quantitative method with descriptive analytic type of research, data collection is done through a questionnaire, with an active employee population of PT. Antam tbk UBPE pongkor. The method of determining the sample using the tabachic and Fidell method, the number of samples used in this study is 60 PT.Antam.Tbk, UBPE Pongkor employee respondents, the data used and processed is primary data. This study uses multiple linear regression analysis using the statistical package for the social sciencess (spss) version 21 program. Based on the results of statistical calculations, it shows that (1) the reward variable has no positive and not significant effect, (2) the punishment variable has a positive and significant effect (3) the reward and punishment variables together have a significant and significant effect on the work motivation of employees at PT Antam Tbk, UBPE Pongkor.
Pengaruh Faktor Budaya dan Psikologis Terhadap Keputusan Nasabah Dalam Memilih Bank Syariah Mandiri KCP Tajur
Authors: Rahmawati Siti , Supriyatna Rio Kartika , Junaedi Dedi , Arsyad Muhammad Rizal
Published: October 2021

Islamic banks are financial institutions that have a wide market potential in Indonesia as one of the applications of the Islamic Islamic economic system in realizing Islamic values ​​and teachings that regulate the economic sector of the Ummah. The number of new financial institutions that have emerged as a Sharia Bank as a business entity is demanded to be able to compete with other financial institutions to survive and increase their profitability. One of the supporting factors for the development of Islamic banking is the public's interest in choosing financial institutions. This research was conducted with the aim of analyzing the influence of cultural and psychological factors partially and simultaneously on customer decisions in choosing Islamic banks at Bank Syariah Mandiri KCP Tajur. The data in this study are primary data obtained from distributing questionnaires to 100 customers of Bank Syariah Mandiri KCP Tajur. The analysis model used to test the hypothesis is simple linear regression with the t test method and the f test using the Statistical Package for the Social Sciences (SPSS) program. The results of the t test of this study indicate that cultural factors have no effect on customer decisions in choosing Bank Syariah Mandiri Tajur, while psychological factors affect customer decisions in choosing Bank Syariah Mandiri Tajur. The results of the F test of this study indicate that cultural and psychological factors have a significant effect on customer decisions in choosing Bank Syariah Mandiri Tajur.
Analisis Strategi Pemasaran Dalam Meningkatkan Penjualan Rumah Makan Pecak Hj. Sadiyah Cilodong Depok
Authors: Ikhsan Reza Fauzi , Devi Abrista , Kosim Ahmad Mulyadi
Published: October 2021

This research begins from a phenomenon that describes the condition of restaurants in Indonesia as inseparable from problems related to marketing strategies, so that it can affect the existence of restaurants in competition and survival. This was a real reflection that cannot be avoided by a business. The research objective was to formulate the most appropriate marketing strategy in accordance with the applied marketing mix by looking at the internal and external conditions that are owned by Pecak Hj. Sadiyah Restaurant. This research was a qualitative descriptive study using marketing strategy theory. Data technique used observation, interviews, documentation, and questionnaires. Data analysis performed was data reduction, data presentation, data lever, and SWOT analysis. These research results have identified the marketing mix, such as product, price, place, and promotion. Then identified indicators in the internal environment as legality, agile operational managers, increasing income every year, quality food, strategic location, halal certification, good cooperation between workers, low prices with high taste, effective distribution channels, and leadership relationships with employees. good. Weaknesses include no offering motivation, no meetings, poor work management, minimal human resources, parking areas, and limited distribution areas. The external environment was able to take advantage of opportunities from abundant raw material sources, developing technology, consumptive culture of society, online delivery services, and high consumer loyalty. Related threats include unstable raw material prices, unstable public interest, shifting of consumers to competitors, and developments since Covid-19, so that the most appropriate marketing strategy was formulated for the development of Pecak Hj. Sadiyah Restaurant in minimizing the weaknesses and threats that threaten.
Peranan Perbankan Syariah Dalam Mendorong Usaha Mikro Kecil dan Menengah Dimasa Pandemi Covid-19
Authors: Muttaqin Hafiz Maulana , Kosim Ahmad Mulyadi , Devi Abrista
Published: October 2021

In the Indonesian economy, Micro, Small and Medium Enterprises (MSMEs) are the business groups that have the largest number. In addition, this group has proven to be resistant to various kinds of shocks to the economic crisis. So it is imperative to strengthen the UMKM group which involves many groups because the UMKM sector has a big contribution to workforce absorption, developing the UMKM sector will be able to absorb more existing workers and of course it will be able to improve the welfare of the workers involved in the workforce. In it so that it can reduce the unemployment rate and in the end it will be used to reduce poverty. The criteria for businesses that are included in MSMEs have been regulated in a legal umbrella based on law. This study aims to determine the role of Islamic Banking in Encouraging Micro, Small and Medium Enterprises (MSMEs) in Indonesian Sharia Banks (BSI) kc. Ahmad Yani Kota Bogor during the Covid Pandemic 19. This study used a descriptive qualitative method and the data used in this study were primary data. This study uses data collection techniques through literature study and interviews. The instrument used in the primary data is an interview with a source from Bank Syaria Indonesia Kc Ahmad Yani, Bogor City. Respondents revealed that the Role of Islamic Banking, especially Islamic Bank Indonesia Kc. Ahmad Yani played an important role in maintaining MSMEs during the Covid-19 pandemic as now because he helped distribute government programs, namely KUR (People's Business Credit), Providing.relaxation or relief to entrepreneurs affected by Covid-19 and facilitating the financing process for entrepreneurs. Which has been determined by the government through PJOK regulation no 11 of 2020.

Keywords: Micro, small and medium enterprises, Islamic banking. Covid-19
Prototipe Kepemimpinan Kiai di Pesantren Modern
Authors: Mukri Rusdiono , Tamam Abas Mansur
Published: October 2021

This study aims to determine the implementation of the management and leadership of kiai Pondok Modern Darussalam Gontor in order to continue to exist and even become a prototype of leadership and management of modern Islamic boarding schools in Indonesia. The study used descriptive qualitative methods which were carried out by collecting data obtained from documentation, observation and interviews, and supported by literature studies, both from books and journals. The results of the study show that the modernity of Pondok Gontor is seen in the implementation of management which is different from Islamic boarding schools in general. Gontor's management is carried out based on the principles of transparency and accountability as well as togetherness. Pondok Gontor adheres to a collective, democratic, and transformational leadership model. This leadership model is proven to be able to bring about change in every student and teacher to achieve high performance. Through its vision and mission, Pondok Gontor strives to produce strong and solid leaders, leaders who have a noble soul and philosophy of life, correct values and are involved in the totality of life in the boarding with high discipline.
Strategi Mengajar Dalam Meningkatkan Mutu Pembelajaran di Kelas 5 Sekolah Dasar Santo Thomas 2 Medan
Authors: Simanjuntak Harlen
Published: October 2021

The general objective of this study is to obtain an empirical description of the strategy for improving the quality of learning in grade 5 elementary schools in Medan. In particular, the objectives of this study are to, (1) find out the strategy for improving the learning quality of grade 5 elementary schools in Medan, (2) find out the results ofstrategies for improving the quality of learning for grade 5 elementary schools in Medan. Where the results of teaching strategies have not had a satisfactory impact on improving the quality of learning in schools. This is viewed from the aspect of teaching strategy, and also the results of the strategy have not given maximum effect onimproving the quality of learning at the elementary school of Santo Thomas 2 Medan.
GRADUATES ON LABOUR MARKET IN ROMANIA. PRECARITY OR RESILIENCE?
Authors: Hatos Roxana
Published: October 2021

Young people on the labor market is a topical issue both in academia and in the latest European and national policies. Young graduates are no exception. They invest in education and want a better match of their studies with the job. Some analyzes performed on AMIGO data and data performed with economics graduates help us to analyze the existing situation. The conclusions show us significant differences in terms of income, in terms of the field of study as well as the mismatch with the graduated field. In terms of gender, there are differences in job satisfaction, with men being more likely to reach leadership positions than women.
PALEOLİTİK DÖNEMDEN GÜNÜMÜZE MEDİKAL İLLÜSTRASYONUN KISA TARİHİ
Authors: KAYA Sefa Ersan
Published: October 2021

İnsan veya hayvan bedenleri Paleolitik dönem mağara duvar resimlerinde ve ilkel olarak yontulmuş figürlerde, çağlar boyunca çeşitli sanatsal ifade biçimi olarak tasvir edilmiştir. Mağara döneminden referans ile başlayan bu iletişim dili, sosyal ve kültürel değişim ile bilginin artması sonucu resim-yazı formları ortaya çıkmıştır. Hem iletişim kaynağındaki hem de metinsel sürecin ayrılmaz bir parçası olan illüstrasyonlar insan vücudu ve onun sistemleri hakkında yapılan gözlem ve incelemelere eşlik etmiştir. Çağlar boyu bilimsel ve toplumsal ilerlemenin izin verdiği ölçüde, illüstrasyon türleri brüt anatomiden çeşitli organ sistemlerine, histolojik preparatlara vb. kadar geniş ölçüde uygulama alanı bulmuştur. Antik Çağ’da taş zemin üzerine oyma tekniği kullanılarak yapılan görseller zaman içerisinde tabletler, metal levhalar ve farklı kâğıt formları ile çeşitlenerek şekillenmiştir. Dönemin kendisi ile çağdaş olan her yeni teknik, tıbbi bilgiyi genişletmiş ve izleyici kitle için erişilebilir kılmıştır. Bu makalede, görsel bir iletişim dili olarak medikal illüstrasyonun gelişim izlerini Antik çağdan günümüze kadar biriken kayıtlarından alınan temsil örnekleri ile açıklanmıştır. Bu örnekler bireyler arası küçük kümelerden küresel sosyal etkileşimde illüstrasyon ve medikal illüstrasyonun dönemsel etkileşimini ortaya koymaktadır.
ÇAĞDAŞ LİF SANATÇILARI PERSPEKTİFİNDEN DİASPORA OLGUSU
Authors: OSKAY Nazan
Published: October 2021

Toplumsal yaşantının her dokusunda farklı bir değişiklik yaşanmaktadır. Bu değişikliklerden biri de insanların tarih boyunca farklı sebeplerden dolayı bulundukları ana vatanlarını terk etmek zorunda bırakılmalarıdır. Yüzyıllardan bu yana gerçekleşen göç hareketleriyle birlikte yaşanan süreçte, ulusal kimlikten diasporik kimliklere kadar uzanan değişim, günümüzde hala tartışılan ve araştırılan önemli konulardan biri olmuştur.
Dünyanın farklı yerlerinde oluşturulan diaspora ile birey üzerinde ‘kimlik’, ‘kültür’, ‘kabul görme’ gibi faktörlerin, değişim ve dönüşüme zemin hazırlaması, sosyal bilimlerin birçok alanının da araştırma konusu olmuştur. Ayrıca sanatın farklı disiplinlerinde de sanatçıların diaspora temasını yapıtlarına taşıdıkları görülmektedir.
Diaspora kavramından yola çıkarak bu çalışmada, “Stories of Migration: Contemporary Artists Interpret Diaspora” (Göç Hikâyeleri: Çağdaş Sanatçılar Diaspora'yı Yorumluyor) isimli sergideki çağdaş lif sanatçılarının, ‘öteki’, ‘bellek’ ve ‘kimlik’ kavramlarının etkisini, kültürün önemli bir parçası olan tekstil teknik ve malzemesi aracılığıyla sanata nasıl yansıttıkları, eserleri üzerinden okunmaya çalışılmıştır.
Farkındalık yaratmak için yapılan bu araştırmada, farklı tekstil malzeme ve tekniklerinin kullanıldığı; bugünün yerini yadırgayan dünyasındaki tarihsel hakikatleri, fiziksel tahribatı ve önyargıyı görsel olarak dile getirmektedir. İzleyiciye üzerinde düşünmesi gereken sorular soran Altı (6) misafir ve otuz sekiz (38) jüri onayından geçmiş sanatçıların eserleri arasından 7 (yedi) farklı eser ele alınmıştır. Araştırmanın örnekleri ele alınırken farklı kültürlerden birey ya da toplulukların yaşadığı diasporik kimlik deneyimi göz önünde bulundurulmuş ve bu örnekler üzerinden analiz ve yorumlar yapılmıştır.
Araştırmada, serginin gerçekleştiği Amerika Birleşik Devletleri The George Washington Üniversitesi ve Tekstil Müzesi’nden elde edilen veriler ile sanatçıların yapıtları çalışmanın görsel doküman kısmını oluştururken, alan yazında ise kitap, tez, makale, internet kaynakları gibi araçlardan yararlanarak genel tarama yapılmıştır.
GRAFİK KAYIT: GERÇEK ZAMANLI GÖRSEL NOTLAR
Authors: BİLGİ İrem
Published: October 2021

Bilgiyi görsel olarak kaydetmek, konuyu anlamak ve akılda kalıcılığı artırmak için sıklıkla kullanılan bir yöntemdir. Herhangi bir konuyu dinlerken görsel notlar almak bireyler için fayda sağlamaktadır. Çizimle ilgisi olmayan bireylerin bile çeşitli karalamalar, çizgiler ve işaretler kullandığı gözlemlenmiştir. Görsel düşünmenin bu olumlu etkileri araştırmacılar tarafından desteklenmektedir. Grafik kayıtlar, toplantı, etkinlik, seminer, eğitim gibi alanlarda gerçek zamanlı olarak kaydedilen görsel notlardır. Gerçek zamanlı görsel notlar katılımcıların konuyu daha iyi kavramasına, konuyla etkileşimde bulunmalarına ve etkinlik bittiğinde konuyu daha iyi hatırlamalarına olanak sağlamaktadır. Etkinliğin sonunda konunun bütününü uzaktan görmeye yardımcı olan görsel bir harita ortaya çıkmaktadır. İlk olarak 1980li yıllarda görsel iletişim tasarımı alanından bağımsız bir şekilde ortaya çıkan grafik kayıt kavramı, günümüzde bir sektör haline gelmiştir. Görsel iletişim tasarımcıların grafik kaydedici başlığı altında çalıştıkları bu sektör, ortaya çıkış nedenleri, kısa tarihçesi ve görsel iletişim tasarımı bağlamında değerlendirilmesi açısından incelenmiştir. Grafik kayıtların görsel iletişim tasarımı alanındaki yerini irdeleyen bu makalede literatür taraması yapılarak nitel araştırma yöntemi kullanılmıştır.
‘BEN’ İNŞASINDA HAYVAN VARLIĞININ ETKİLERİNİN SANATSAL ÖRNEKLERLE İNCELENMESİ
Authors: SEZER Emrah
Published: October 2021

İnsan, kurduğu dünyada kendini ‘ben’ olarak var edebilmek için, bir ‘başka’ya ihtiyaç duymaktadır. ‘Ben’in, kendini karşılaştıracağı varlığın da onun gibi duygu ve davranış becerilerine sahip olması gerekmektedir. Bu nedenle, doğada insana en yakın varlık olan hayvan, ‘ben’in karşılaşacağı ’başka’ olarak konumlanmaktadır. Bu çalışmanın amacı, insan olan öznenin ‘ben’ kurulumunda hayvanın, insanın ‘başka’sı olarak yer aldığı durumları araştırmak ve felsefi düşünceler ile yapılan sorgulamaların, sanat tarihine yansımalarını incelemektir. Çalışmanın ilk bölümünde, doğada birlikte var olduğu hayvandan, insanın kendini nasıl ayırdığı ve insan-hayvan arasında yaratılan ikiliğin ortaya çıkışı, Antik Yunan’dan itibaren incelenecektir. İkinci bölümde Maurice Merleau-Ponty, Emanuel Levinas ve Jacques Lacan’ın felsefeleri üzerinden ‘ben’ kurgusunun yapılışı ve bu kurguda ‘başka’nın gerekliliği araştırılacaktır. Üçüncü bölümde ise inceleme konusu olan insan-hayvan ilişkisi üzerine sorgulamaların sanata yansımaları değerlendirilecektir. Değerlendirmeler, et ve beden kavramları ile Rembrandt ve Francis Bacon’un resimlerini, Emanuel Levinas tarafından ‘ben’in, karşısındakini tanıma aracı olarak ifade edilen ‘yüze sahip olma’ durumu ile Kate Clark’ın heykellerini ve Merleau-Ponty’nin, insan ve hayvan arasında yarattığı öznelerarası dünya fikri ile Joseph Beuys ve Oleg Kulik’in performanslarını ele alacaktır.
MÜZİK ÖĞRETMENİ ADAYLARININ MAKAMSAL, MODAL VE TONAL DİZİ BİLGİLERİNİN KARŞILAŞTIRILMASI
Authors: KARAASLAN Serkan , ÖZGÜR Ülkü
Published: October 2021

Araştırmanın amacı, müzik eğitiminde modal dizilerin, makamsal ve tonal dizilere göre müzik eserlerinin dizi ve karar tonlarını belirlemedeki rolünü ortaya koymaktır. Araştırmanın çalışma grubu, 2018-2019 öğretim yılı Gazi Üniversitesi Gazi Eğitim Fakültesi Güzel Sanatlar Eğitimi Bölümü Müzik Eğitimi Anabilim Dalı güz dönemi son sınıf öğrencilerinden oluşmaktadır. Bu çalışmada nitel araştırma yöntemi olan durum çalışması tipi kullanılmıştır. Öğrencilere işitsel ve görsel testler uygulanmıştır.
INTERNET OF NANOTHINGS (IoNT) – A CONCISE REVIEW OF ITS HEALTHCARE APPLICATIONS AND FUTURE SCOPE IN PANDEMICS
Authors: Prabhu R. Senthil , Ananthi D. Sabitha , Rajasoundarya S. , Janakan R. , Priyanka R.
Published: October 2021

Technologies that could allow literally billions of everyday objects to communicate with each other over the internet have enormous potential to change all our lives. The Internet of Things (IoT) is a transformative development, these technologies are a way of boosting productivity, keeping us healthier, making transport more efficient, reducing energy needs and making our homes more comfortable. In recent years, Internet of Things (IoT) and Internet of Nanothings (IoNT) have drawn significant research attention in numerous fields such as Healthcare, Defence, Environmental monitoring, Food and water quality control etc., There are various transformations such as Smart cities, Smart homes, Smart factories, Smart transportation, due to IoT and IoNT. Health care delivery requires the support of new technologies like IoT, IoNT to fight and look against the new pandemic diseases. For the past two years COVID-19 spreaded over worldwide including India, are fighting with pandemic disease and still looking for a practical and cost-effective solution to face the problems arising in several ways. To minimize the person to person, contact and to maintain social distancing various technologies are utilized, among them IoT and IoNT play a major role in healthcare system and allied fields. This review mainly discuss about the IoT, IoNT, its components and various applications in healthcare and allied fields.
Kecanduan Gadget di Masa Pandemi covid-19 pada Siswa Kelas XII MIPA SMAN 1 Sutojayan Kabupaten Blitar
Authors: Bintari Ramadhanti Husnah
Published: October 2021

Adanya pandemi Covid-19 menuntut adanya pembelajaran secara daring dengan menggunakan gadget ternyata menimbulkan dampak negatif yaitu siswa terstimulasi mengakses aplikasi lain sehingga  meningkatkan kenyamanan dan kemampuan eksplorasi siswa pada penggunaan internet. Hal ini meningkatkan resiko kecanduan pada siswa. Tujuan penelitian ini adalah mengetahui tingkat kecanduan gadget di masa pandemi Covid-19 pada siswa kelas XII MIPA SMAN 1 Sutojayan Kabupaten  Blitar.

Penelitian ini merupakan penelitian deskriptif. Populasinya seluruh siswa kelas XII MIPA SMAN 1 Sutojayan Kabupaten Blitar dengan total 176 orang. Jumlah sampel 122 responden, dengan teknik sampling proportional random sampling. Variabel yang diteliti adalah tingkat kecanduan gadget di masa pandemi Covid-19. Instrumen penelitian yang digunakan adalah kuesioner SAS (Smartphone Addiction Scale). Analisa data menggunakan analisis univariat.

Hasil penelitian menunjukkan sebagian besar responden berada pada tingkat kecanduan sedang yaitu 93 responden (75%), sebagian kecil berada pada kategori kecanduan berat dan ringan yaitu 23 responden (20%) dan 6 responden (5%). Hasil penelitian itu dimungkinkan karena adanya sarana dan prasana yang disediakan orang tua di rumah, untuk mencari informasi,mengerjakan tugas, bermain game dan menonton vidio/film/vlog.

Oleh karena itu, pemberian konseling kepada orang tua dan siswa tentang cara bijak penggunaan gadget serta kontrol diri dan selektivitas dalam penggunaan teknologi informasi dan komunikasi. Pembinaan dan pengawasan orang tua sangat dibutuhkan untuk menurunkan resiko kecanduan pada siswa.
UJI EFEKTIVITAS ANALGESIK EKSTRAK KOMBINASI JAHE (Zingiberaceae Officinale) DAN JARAK PAGAR (Jatropha curcas) PADA MENCIT(Mus Musculus
Authors: Septiawati Dwi
Published: October 2021

Nyeri pada dasarnya merupakan suatu reaksi fisiologis berupa reaksi protektif tubuh sebagai mekanisme untuk menghindari stimulus yang membahayakan bagi tubuh. Masyarakat saat ini menggunakan herbal sebagai pelengkap pengobatan primer yang diterima. Jahe merupakan tanaman rimpang yang memiliki banyak khasiat, salah satunya adalah sebagai analgetik dan antiinflamasi. Jarak pagar memiliki aktivitas farmakologi diantaranya melancarkan peredaran darah, menghilangkan bengkak, menghentikan pendarahan, dan menghilangkan gatal. Penelitian ini bertujuan untuk melihat perbandingan efek analgesik ekstrak kombinasi jahe dan jarak pagar dengan paracetamol. Penelitian ini merupakan penelitian eksperimental dengan kelompok perlakuan paracetamol dan kombinasi jahe dan jarak pagar. Pada penilitian ini menggunakan lima kelompokkontrol positif, control negative, dan kelompok perlakuan yaitu kelompok diberi ekstrak kombinasi jahe dan jarak pagar dengan 3 dosis berbeda yaitu 16 mg/ 20gr BB, 32 mg/20gr BB, 48 mg/20gr BB. Efek analgesik dilihat dengan menghitung jingkatan mencit dalam 5 menit, berupa mengangkat kedua kaki depannya atau meloncat ke atas setelah diberi induksi asam asetat 1%.Hasil pengamatan menunjukkan kandungan senyawa kimia pada ekstrak kombinasi jahe dan jarak pagar terbukti memiliki efek analgesik dibanding dengan kelompok kontrol.

Kata kunci: Analgesik, Paracetamol, Jahe, Jarak pagar
PERBEDAAN PENURUNAN SKALA NYERI PUNGGUNG PADA IBU HAMIL TRIMESTER III DENGAN SENAM HAMIL DAN TANPA SENAM HAMIL DI KECAMATAN MOJOSARI MOJOKERTO
Authors: Mardiana Heppy
Published: October 2021

Pendahuluan Pada kehamilan sering muncul keluhan salah satunya nyeri punggung yang banyak dialami oleh Ibu hamil di trimester tiga. Selama pandemi covid-19 terkait dengan kebijakan pemerintah bahwa pasien hamil yang tidak urgent, tidak perlu konsultasi serta senam hamil ditiadakan. Tujuan penelitian ini adalah mengetahui perbedaan penurunan skala nyeri punggung pada ibu hamil trimester III dengan senam hamil online dan tanpa senam hamil di Desa Seduri Kecamatan Mojosari-Mojokerto.

Metode Desain yang digunakan adalah Quasy Eksperiment dengan menggunakan pendekatan two group pre-post test design.Populasi dalam penelitian ini adalah semua Ibu hamil di Desa Seduri sebanyak 40 orang. Teknik pengambilan sampel menggunakan Total sampling, terdiri dari 20 kelompok kontrol dan 20 kelompok perlakuan. Penelitian dilakukan selama 3 minggu. Senam hamil online menggunakan Google meet selama 2x/minggu dan pengumpulan data menggunakan lembar observasi.

Hasil Uji komparasi menggunakan Independent t-test, dan didapatkan hasil t hitung 0.085(sig>0.05) berarti ada perbedaan penurunan skala nyeri punggung bawah pada Ibu hamil yang melakukan senam hamil dan yang tidak melakukan senam hamil.

Kesimpulan Senam hamil perlu dilakukan oleh Ibu di rumah selama pandemi Covid 19  karena memberikan efek rileks pada tubuh, sehingga membantu mengeluarkan hormone endorphin yang membuat Ibu bahagia.

 

Kata kunci: Kehamilan, Senam hamil, Nyeri punggung.
Tissue Engineering Heart Valves – a Review of More than Two Decades into Preclinical and Clinical Testing for Obtaining the Next Generation of Heart Valve Substitutes
Authors: Simionescu Dan , Harpa Marius Mihai , Simionescu Agneta , Oprita Codrut , Movileanu Ionela
Published: October 2021

Well documented shortcomings of current heart valve substitutes – biological and mechanical prostheses make them imperfect choices for patients diagnosed with heart valve disease, in need for a cardiac valve replacement. Regenerative Medicine and Tissue Engineering represent the research grounds of the next generation of valvular prostheses – Tissue Engineering Heart Valves (TEHV). Mimicking the structure and function of the native valves, TEHVs are three dimensional structures obtained in laboratories encompassing scaffolds (natural and synthetic), cells (stem cells and differentiated cells) and bioreactors. The literature stipulates two major heart valve regeneration paradigms, differing in the manner of autologous cells repopulation of the scaffolds; in vitro, or in vivo, respectively. During the past two decades, multidisciplinary both in vitro and in vitro research work was performed and published. In vivo experience comprises preclinical tests in experimental animal model and cautious limited clinical translation in patients. Despite initial encouraging results, translation of their usage in large clinical scenarios represents the most important challenge that needs to be overcome. This review purpose is to outline the most remarkable preclinical and clinical results of TEHV evaluation along with the lessons learnt from all this experience.
The Investigation of Combined Na+/Ca2+ Exchanger and the L-type Ca2+- Channel Inhibition in Langendorff-Perfused Isolated Guinea Pig Hearts
Authors: Prorok János , Veisbart Annamária , Lipka Dóra , Jost Norbert
Published: October 2021

Objective

The sodium/calcium exchanger (NCX) and the L-type Ca2+-channel (LTCC) are nowadays considered the major transmembrane transport mechanisms that control Ca2+ homeostasis. In pathophysiological conditions the altered function of these currents may influence the Ca2+ homeostasis and cardiac contractility and thereby, may enhance the development of severe tachyarrhythmias. The blockade of NCX current has been proposed as possible approach in the prevention and/or suppression of arrhythmias; however, this mechanism is not always favourable because the inhibition of both modes of NCX may induce Ca2+-overload. The decrease of the Ca2+ level by partial LTCC inhibition may be beneficial in increasing the antiarrhythmic efficacy. Therefore, the aim of our study was to investigate the antiarrhythmic effects of combined NCX and LTCC blockade in the ex vivo guinea pig arrhythmia model.

Methods

We have performed Langendorff experiments in isolated guinea pig hearts. We have recorded electrocardiograms (ECG) and left ventricle pressure. We have applied 1 μM ORM-10962 (ORM), a compound that block NCX current and 30 nM nisoldipine for the inhibition of LTCC. Arrhythmias have been provoked by decreasing the activity of the sodium/potassium pump with 5 μM ouabain.

Results

We found that neither LTCC nor NCX blockade alone increased, while the combined inhibition of the two currents significantly delayed (p<0.05) the mean time of appearance of ouabain-induced ventricular fibrillation. The heart frequency was affected by none of the drugs, only the left ventricular pressure (end-systolic and diastolic difference) was significantly elevated by ORM (p<0.001).

Conclusion

In the Langendorff-perfused guinea pig heart, specific, combined NCX and LTCC blockade may be favourable than the inhibition of NCX or LTCC alone. However, further investigations are necessary to identify the pathological settings in which this combined cardiac drug therapy may be a potential new approach.
In Silico Analysis of Novel Titin Non-Synonymous Missense Variants Detected by Targeted Next-Generation Sequencing in a Cohort of Romanian Index Patients with Hypertrophic Cardiomyopathy
Authors: Micheu Miruna Mihaela , Oprescu Nicoleta , Popa-Fotea Nicoleta-Monica
Published: October 2021

Background and aim

Most of detected variants in cardiogenetic panels are still classified as variants of unknown significance, requiring supplementary analyses for a definite classification. Performing further in-depth studies on such vast number of candidates is unfeasible. We sought to prioritise the novel nonsynonymous missense variants identified in titin gene (TTN) in a cohort of Romanian index cases with hypertrophic cardiomyopathy (HCM).

Methods

45 unrelated probands with HCM were screened by targeted next generation sequencing (NGS) covering all TTN exons. A stepwise strategy was used to select and prioritize the candidate variants for subsequent investigation.

Results

Using rigorous bioinformatic filtering, 7 novel TTN nonsynonymous missense variants were identified and were the subject of in silico sequential analysis. 4 of the 7 variants were predicted to be possibly pathogenic by the Mendelian Clinically Applicable Pathogenicity (M-CAP) algorithm. Of these, three sequence variants (c.30392G>T, c.2518G>T, and c.49G>T) were also predicted to be destabilizing according to the second computational tool (TITINdb) and were designated as likely function-impacting.

Conclusions

Herein we presented our strategy to hand-pick the novel TTN missense variants to be considered for further experimental studies. By applying various in silico tools, we restricted the list of sequence variants to be investigated to those most likely to be disease-associated, and thus reducing the need to perform expensive and time-consuming additional studies.
Review of approaches and methods to assess the comparative efficiency of technological processes and production
Authors: Kovalev D.I. , Kozlova M.F. , Olshevskaya O.I. , Mansurova T.P.
Published: October 2021

The article provides an overview of approaches and methods to assess the comparative efficiency of technological processes and production. It is known that the most common methods are those that assess production based on the analysis of the states of control objects, as components of production, taken into account in the automated control system, or analysis of the course of the technological process. It is shown that efficiency is the most general, defining property of any purposeful activity, which from the cognitive point of view is revealed through the category of the goal and is objectively expressed by the degree of goal achievement, taking into account the cost of resources and time. Increasing the efficiency of the enterprise is carried out using methods of analyzing the structures of enterprises, which allow, with the transparency of the structure and organization of production, to carry out accurate and high-quality monitoring of the state of the objects of the enterprise and their management. The analysis of comparative efficiency is an important component of production processes. The results of the analysis allow you to debug the work of the enterprise already at the initial stages of reducing the efficiency of its functioning. An important task is to find a mathematical basis for analyzing the efficiency of enterprises. The paper discusses parametric and nonparametric methods for assessing comparative efficiency. The main difference between parametric methods is the econometric estimation of parametric functions in the study of the interaction of costs and resources. The authors pay attention to the nonparametric DEA method, which, due to its characteristics, has a number of advantages and features. The method allows you to obtain a comprehensive performance indicator for each enterprise, and can also take into account multiple input and output variables. These features of the DEA method make it possible to successfully apply it in determining the indicator of the comparative efficiency of enterprises.
BENEFÍCIOS DO SEGUIMENTO FARMACOTERAPÊUTICO PARA O TRATAMENTO DE PACIENTES COM DIABETES MELLITUS: UMA REVISÃO INTEGRATIVA
Authors: Silva Gonçalves Samantha Aparecida , Silva Simone , Bitencourt Santos Barros Gérsika
Published: October 2021

Objetivo: Analisar o benefício do acompanhamento farmacoterapêutico durante a terapia medicamentosa e não medicamentosa de pacientes com diabetes mellitus. Métodos: Trata-se de uma revisão integrativa da literatura sobre o acompanhamento de pacientes com terapia antidiabética e que possuem ou não comorbidades secundárias. Os artigos foram analisados por meio das bases de dados, Pubmed, Scielo, Lilacs publicados entre os anos de 2016 a 2021. Resultados: Foram selecionados 20 artigos para comporem esse artigo de revisão. Os artigos correlacionam a prática do seguimento farmacoterapêutico dos pacientes de diabetes mellitus e os benefícios trazidos para a resposta terapêutica. Há também estudos sobre o benefício da atividade física associada a fármacos diabéticos que melhoraram sua glicemia de jejum, pós prandial e hemoglobina glicada. Quanto à idade observou que há um predomínio de pessoas com uma idade acima de 41 anos, 50% de 41 a 60 e 23% de 61 a 80 anos. Este fato deve se por se relacionar ao aumento de doenças crônicas, cujo o avanço da idade é proporcional ao aumento da incidência de diabetes mellitus.  Considerações finais: Houve uma percepção de que é importante o acompanhamento farmacoterapêutico dos pacientes com diabetes mellitus, pois muitos desenvolvem outras doenças relacionadas ao mal-uso do fármaco por falta de resposta farmacológica ou apresentam reações adversas relacionadas aos medicamentos administrados.
Nghiên cứu các đặc trưng cơ học của bê tông sử dụng cát mịn phối trộn cát nghiền trong xây dựng cầu
Authors: Nguyễn Đức Dũng , Nguyễn Duy Tiến , Thái Khắc Chiến
Published: October 2021

Đồng bằng sông Cửu Long đang trong giai đoạn xây dựng cơ sử hạ tầng với hàng loạt các công trình giao thông lớn đã và đang được triển khai như cao tốc Trung Lương – Mỹ Thuận, cao tốc Bến Lức – Long Thành, cầu Bình Khánh, cầu Thủ Thiêm 2. Trong khi đó nguồn cát vàng hạt lớn để chế tạo bê tông xi măng ngày càng trở lên khan hiếm. Để đáp ứng nhu cầu xây dựng các dự án đã tiến hành phối trộn cát mịn (CM) với cát nghiền thô còn gọi là đá mi (ĐX) để tạo ra cát hỗn hợp để dùng như một giải pháp thay thế. Nội dung bài báo này trình bày kết quả nghiên cứu các tính chất cơ học của bê tông sử dụng cát hỗn hợp với cấp cường độ C40 phù hợp để áp dụng cho xây dựng cầu, đồng thời cũng xây dựng các phương trình quan hệ giữa các đặc trưng cơ học của bê tông với các tính chất của vật liệu cát hỗn hợp nhằm đưa ra các đề xuất phục vụ công tác thiết kế và thi công cầu với loại vật liệu đặc trưng này.
Characteristics and corrosion protection of polypyrrole doped with salicylate anions
on CT3 steel passivated by molydate
Authors: Hoang Thi Tuyet Lan , Lai Thi Hoan
Published: October 2021

In recent years, the conducting polymers have attracted much attention in research and development because of their applications in medical and civil engineering. Here, the salicylate doped polypyrrole films were prepared on the carbon steel surface and their corrosion protection in 3 % NaCl solution were studied. Polypyrrole (Ppy) film was electrochemically synthesised with constant current techniques in a sodium salicylate solution (0.05M, 0.1M, 0.15M) and 0.1M pyrrole monomer on mild CT3 steel electrode passivated by molybdate. The morphological, structural, composition and thermal properties of salicylate doped Ppy films were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and thermogravimetric analysis (TGA) techniques. The anti-corrosion ability of these films was assessed by electrochemical measurements in 3 % NaCl solution. The obtained results suggested that salicylate anions contributed in corrosion protection ability of Ppy films for mild steel electrode. The concentration of sodium salicylate of 0.1M and pyrrole of 0.1M is most suitable for preparation of good protection coating. The self-healing mechanism has been also mentioned for salicylate doped Ppy films on CT3 steel substrate.
Experimental evaluation on engineering properties and microstructure of the high-performance fiber-reinforced mortar with low polypropylene fiber content
Authors: Vu Viet Hung , Nguyen Tuan Cuong , Nguyen Huu Duy , Ngo Nguyen Ngoc Tho , Huynh Trong Phuoc
Published: October 2021

Recently, high-performance fiber-reinforced mortar/concrete (HPFRM) has been researched and developed in many fields such as repair, maintenance, and new construction of infrastructure works due to its high strain capacity and tight crack width characteristics. Optimizing the design of mixture proportions and structures using HPFRM is still a complex mechanical and physical process, depending on the design principles, specific site conditions, and their local materials. This study aims to develop an HPFRM with low polypropylene fiber content by using locally available ingredients in Southern Vietnam to address the deficiencies commonly observed in traditional cement grout mortars. Three mixture proportions were prepared with different water-to-binder (w/b) ratios of 0.2, 0.25, and 0.3. Then, the performance of HPFRM was evaluated in both fresh and hardened stages. Additionally, the microstructural characteristics of each mix design were also assessed through scanning electron microscope observation. The experimental results showed that the optimum w/b of 0.25 and a fixed dosage of 0.6% polypropylene fiber produced positive impacts on the rheological, mechanical properties, and also ductility of the high-performance mortar. It was concluded that HPFRMs are promising for cost-effective and sustainable cement mortars.
Relationship between Educational and Occupational Status of Parents and their involvement in Adolescents’ Academic Achievements in Agona West Municipality
Authors: Boateng Akosua Serwaa-Adomako , Wilson Kwesi Nkum
Published: October 2021

The study was conducted to know whether education level and occupational status of parents in the Agona West Municipality of Ghana have any significant relationship with parental involvement in adolescent academic achievement. The cross-sectional survey and correlational research designs were employed and data were collected with the use of a structured questionnaire. The questionnaire was self-administered to the 310 basics 8 pupils that were purposively sampled from the 6 randomly selected schools. Findings revealed that, in the Agona West Municipality, education level of both mothers and fathers had a significant relationship with parent’s ability to engage in school based activities of pupils as well as encouraging the pupils with respect to their academic achievement. However, occupational status of only fathers had a significant relationship with parent’s ability to involve in school based activities. Additionally, no significant relationship between a parent’s occupational status and their ability to encourage pupils with respect to their academic achievement was found. The authors provide guidance implications and recommendations based on the findings from the study.
ВИРТУАЛДЫ ЖӘНЕ ТОЛЫҚТЫРЫЛҒАН ШЫНДЫҚ ТЕХНОЛОГИЯЛАРЫН ОҚУ ПРОЦЕССІНДЕ ҚОЛДАНУДЫҢ ПРАКТИКАЛЫҚ НЕГІЗІ
Authors: Зухра Кусайновна Калкабаева  , Нуржан Тажибаевич  Шындалиев
Published: October 2021

"Қазіргі таңда виртуалды және толықтырылған шындық технологияларының қолданылу аясы көптеген салаларды қамтиды. Күнделікті өмірде қолданылып жүрген әлеуметтік желілер мен көңіл көтеруге арналған ойындардан бастап қоғам өміріне маңызды білім беру, медицина, техника салаларында да көптеп пайдаланылуда. Мақалада оқу процессінде қолданысқа енгізілген виртуалды және толықтырылған шындыққа негізделген маңызды қосымшалардың жұмысына шолу жасаймыз. Аталған қосымшаларды білім беруде сандық ресурс ретінде пайдалану білім алушылардың ұсынылып отырған пәнге деген қызығушылығын арттырып, оқу сапасын көтерудің бірден бір жолы болып табылады. Сонымен қатар, берілген мақалада виртуалды және толықтырылған шындық қосымшаларын құруға арналған бағдарламалық жабдықтарға талдау жасалып, жұмыс жасау мүмкіндіктері қарастырылды. Талдау нәтижелері бойынша Vuforia және Unity 3D бағдарламалық жабдықтары тиімді екендігін ескеріп, алдағы жұмыстарымызда осы бағдарламаларды пайдалануға шешім қабылдадық. Аталған бағдарламалық жабдықтарды эксперимент барысында қолданып, тиімділігіне тағы да көз жеткізетін боламыз. Жоғары оқу орынында VR\AR технологияларының қолданылу деңгейін анықтау мақсатында Л. Н. Гумилев атындағы Еуразия ұлттық университеті мен Қ. Жұбанов атындағы Ақтөбе өңірлік университеті білім алушылары арасында сауалнама жүргізілген болатын. Сауалнама нәтижелері бойынша білім алушылардың VR\AR құрылғыларын сабақта қолданғысы келетіндігін, виртуалды және толықтырылған шындық қосымшаларын құруды үйренуге деген қызығушылығын байқадық. "
ОРГАНИЗАЦИЯ ОБУЧЕНИЯ УЧАЩИХСЯ С НАРУШЕНИЕМ СЛУХА ИНОСТРАННОМУ ЯЗЫКУ: ЗАРУБЕЖНЫЙ И КАЗАХСТАНСКИЙ ОПЫТ
Authors: Гульмира Баянжановна Мадиева  , Елена Юрьевна Сысоева
Published: October 2021

"Настоящая статья посвящена одной из важных тем инклюзивного образования – обучению учащихся с нарушением слуха, в частности, обучению иностранным языкам. Приводятся результаты теоретического обзора научной литературы с целью сравнения имеющегося зарубежного (польского) и казахстанского опыта организации обучения иностранному языку учащихся с нарушением слуха, его особенностей. Дано описание основных моментов организации образовательного процесса, методов обучения, используемых при обучении иностранному языку учащихся с нарушением слуха в контексте польского и казахстанского образовательных процессов. Представлены результаты анализа опыта обучения иностранному языку в Казахстане в условиях специальной коррекционной школы № 5 для детей с нарушением слуха г. Алматы, полученные в результате наблюдения за педагогическим процессом на уроках английского языка. Были описаны используемые методы обучения и имеющиеся проблемы, с которыми сталкиваются как учителя, так и ученики. Полученные результаты позволяют сделать выводы о имеющихся схожих и различных моментах в организации и проведении обучения в Казахстане и Польше, а также необходимости дальнейшего совершенствования процесса обучения учащихся с нарушением слуха иностранному языку. "
ЖОҒАРЫ ӨНІМДІ ЕСЕПТЕУЛЕРДІ ЖҮЗЕГЕ АСЫРУДЫҢ ОҚУ-ӘДІСТЕМЕЛІК НЕГІЗДЕР
Authors: Меруерт Серік  , Гульмира Жумагалиевна  Ерланова
Published: October 2021

"Бұл мақалада оқу-әдістемелік негіздерді, оларды құрастыру мен қолдану ерекшеліктері, сапасын талдау және жоғары оқу орнының оқу үдерісіне енгізуді оңтайландыру, жоғары оқу орындарында білім бағдарламаларын әдістемелік қамту, оқу-әдістемелік кешендерді құрастыру мен қолдану ерекшеліктері сияқты сұрақтарды қарастыратын бірқатар ғылыми еңбектер мен педагогикалық әдебиеттерге, сонымен қатар, жоғары өнімді есептеулерді (ЖӨЕ) оқыту жағдайы бойынша әлемдегі алдыңғы қатардағы жоғары оқу орындарының тәжірибесіне шолу жасалады. ЖӨЕ жүзеге асырудың оқу-әдістемелік қамтамасыз етілуі сипатталады. Мысал ретінде ақпараттық технология саласының болашақ мамандарын даярлауда жоғары жылдамдықты есептеулерге арналған оқу курстарының оқу-әдістемелік негіздері алынады. Сонымен бірге, оқу курсының мақсаты, оқытудың негізгі әдістемелік қамтылуы талқыланады. Оқу үдерісін ұйымдастыруда пәннің оқу-әдістемелік кешенін құру, цифрлық білім беру ресурстары мен оқу-әдістемелік құралдары туралы айтылады. Берілген тақырыптар бойынша әртүрлі әдістерді қолдану арқылы жылдам есептеулердің мысалдары келтіріліп, салыстырмалы талдау жасалады. Сол арқылы тиімді есептеу әдістері анықталады. Курсты оқу барысындағы негізгі құзыреттіліктері беріледі. Құрастырылған әдістемелік құралдарды оқу үдерісіне енгізу нәтижесі беріліп, оның тиімділігін анықтайтын эксперименттің қысқаша қорытындысы келтіріледі. "