bluuebunny/crossref_metadata_2025 huggingface dataset:
As dificuldades enfrentadas na ausência de profissionais farmacêuticos nas farmácias hospitalares
Authors: De Oliveira Luana Carvalho , Gouveia Fabíola Leite , Da Silva Willams Alves , Da Silva Camila Macaúbas , De Menezes Danielle Lima Bezerra , Macedo Pollyana Cristina de Oliveira , Silva Janayze Suéllen de Lima Mendes , Bandeira Mary Anne Medeiros
Published: May 2023

As evoluções tecnológicas e a necessidade da promoção da saúde para a população vêm abrindo horizontes de fortalecimento farmacêutico, e trazendo base para a prescrição farmacêutica, consolidando a Farmácia Clínica e a autoridade técnica do profissional, exercendo assim, um papel estratégico na mudança da saúde no país. O Farmacêutico sempre acompanhou a humanidade, pois o homem sempre conviveu com doenças e, por muito tempo, o farmacêutico exerceu apenas o papel de manipular medicamentos, com a evolução dos séculos e ascensão da indústria, houve um deslocamento do seu principal ofício. Para resgatar o Farmacêutico e aproximá-lo da população e equipe, surgiram a Farmácia Clínica e a Atenção Farmacêutica, levando a imagem do farmacêutico para o cuidado ao paciente no hospital e, posteriormente, nos ambulatórios e comunidades. Aplicando seus conhecimentos para garantir o uso racional de medicamentos, otimizando terapias, trazendo segurança e custo-benefício ao uso adequado de medicamentos. Compreendendo atitudes, valores éticos, comportamentos, habilidades, compromissos e corresponsabilidades na prevenção de doenças, promoção e recuperação da saúde, de forma integrada à equipe multiprofissional. Utilizando também métodos de Seguimento Farmacoterapêutico, podendo seguir seu atendimento com determinação dos resultados obtidos.
A vítima no contexto da criminologia contemporânea
Authors: De Oliveira Guilherme Vicente , De Sousa Gaspar Alexandre Machado
Published: May 2023

Ao longo dos períodos históricos a vítima assumiu diversos papéis no fenômeno criminal. Ora como protagonista (vingança privada), ora como coadjuvante (vingança pública). No final da idade moderna, início da idade contemporânea (século XVIII), sob influência do movimento filosófico conhecido como Iluminismo ou Ilustração, o direito penal e a criminologia foram sistematizados segundo critérios científicos, surgindo a partir daí diversas escolas criminológicas que se debruçaram sobre o evento criminoso a fim de compreendê-lo e controlá-lo. A criminologia desenvolveu-se paulatinamente nestes dois últimos séculos ampliando seu objeto de estudo a fim de hoje abarcar quatro elementos: crime, criminoso, a vítima e o controle social. O presente artigo, tem como fito compreender o trato da vítima no contexto do evento criminoso ao longo dos períodos históricos, sua sistematização como objeto de estudo da criminologia, operada no pós-segunda guerra mundial, nascedouro da vitimologia, e qual a repercussão disso na atualidade, sobretudo na construção de políticas criminais, na segurança pública e no sistema processual penal, especialmente a vista do crescente movimento de consensualização do direito penal que dá ênfase a hodierna etapa de redescobrimento da vítima.
Apendicite aguda: aspectos fisiopatológicos e manejo terapêutico
Authors: Silva Vitoria Viana , Macedo Mariana Machado Rocha , Melo Iara Tiene de Lima , Pompei Vinícius Abritta , Kneip Luiza Baptista de Oliveira , Fernandes Luisa Mairink , Souza Gustavo Meirelles , Albuquerque Ana Luíza Carvalho , Arruda Vitória Pimenta , De Andrade Maria Júlia Vasconcelos Fernandes
Published: May 2023

A Apendicite Aguda (AA) é caracterizada pela inflamação do apêndice. Sua prevalência é mais frequente em homens quando comparado às mulheres. O risco de desenvolver a doença ao longo da vida é de aproximadamente 1 em cada 11 pessoas. A teoria mais consistente a respeito da etiologia da AA gira em torno de uma obstrução luminal do fundo cego do apêndice. Os principais sintomas da doença são dor em cólica periumbilical que se intensifica por um período de 24 horas e se irradia para a fossa ilíaca direita, acompanhada de náuseas, vômitos, febre e perda de apetite. Alguns sinais como o de Romberg, de Rosving, e o de Psoas são descritos para investigação da doença. Ademais, sistemas de pontuação clínica, como o escore de Alvarado, associado a exames de imagem, como a ultrassonografia e a tomografia computadorizada, podem ser muito úteis para comprovação diagnóstica, além de contribuírem para a diferenciação entre apendicite complicada e não complicada. No que se refere ao diagnóstico diferencial, existem importantes doenças que precisam ser lembradas e que possuem uma sintomatologia parecida, como a Doença Inflamatória Pélvica, torção de cisto ovariano, linfadenite mesentérica e intussuscepção intestinal. O tratamento da AA, na apendicite não complicada, possui como padrão ouro a apendicectomia. Todavia, na AA complicada, com exceção dos pacientes com peritonite difusa, existem indicações para o tratamento conservador com antibioticoterapia, apesar de não ser um consenso.
Sangue vivo isolado nas fezes de recém nascidos e o desafio diagnóstico de proctocolite alérgica
Authors: De Carvalho Vânia Gameiro , Machado Lucas Rossi , Stival Paula Gameiro Colenghi , Barione Maria Júlia de Sousa , Sandoval Ana Luísa Mitri
Published: May 2023

A alergia à proteína do leite de vaca (APLV) é a principal causa de alergia alimentar na infância, com manifestações clínicas variadas, incluindo diversos órgãos, sistemas e graus de comprometimento, podendo ser classificada, de acordo com seu mecanismo imunológico, como Alergia Imunoglobulina E (Ige E) mediada, Alergia mista ou Alergia não IgE mediada. Entre as reações não IgE mediadas encontra-se a Proctocolite Alérgica Induzida pela Proteína Alimentar (FPIAP, do inglês food protein induced proctocolitis), a qual, no período neonatal, manifesta-se frequentemente na forma de sangramento retal. A FPIAP, no entanto, devido à ampla gama de diagnósticos diferenciais, permanece um tópico controverso. Além disso, poucos estudos têm usado o padrão-ouro de diagnóstico, o Teste de Provocação Oral (TPO), para a confirmação do diagnóstico de APLV, sendo que a maioria das estimativas sobre a frequência de APLV utilizam outros métodos diagnósticos, como prick-test, histologia e autopercepção, em manifestações variadas de apresentação clínica, o que pode superestimar a frequência real da doença. De acordo com isso, é evidente que a caracterização diagnóstica da proctocolite alérgica em recém nascidos necessita de um consenso, em termos de investigação diagnóstica e condutas, baseado em evidências científicas, para que, dessa maneira, seja evitado o superdiagnóstico da doença e, consequentemente, restrições desnecessárias da proteína do leite de vaca e a introdução inapropriada de fórmulas infantis hipoalergênicas de alto custo.
A prevalência da Esofagite Eosinofílica no Brasil – uma revisão de literatura
Authors: Queiros Mariana Carvalho , Bandeira Lucas Alves , Souza Ana Elisa de Freitas , de Paiva Stephany Fernandes , Alcântara Vitor Silva , Mouro Maria Fernanda , Dos Santos Isabella Ribeiro , Alves Hyago Rodolfo Franco , Marinheiro Nicolle Pires Bastos , Perissê Rafaella Afonso Tormin
Published: May 2023

OBJETIVO: O presente artigo tem como objetivo revisar dados da literatura sobre o tema Esofagite Eosinofílica (EE), visando, por meio de conceitos atualizados, ampliar o conhecimento da doença através de seus aspectos etiológicos e fisiopatológicos, bem como discutir sua incidência e prevalência no Brasil. MÉTODOS: Trata-se de uma revisão sistemática de literatura, na modalidade exploratória. Os trabalhos encontrados foram submetidos, de forma integral, a uma análise crítica que discutiam a história natural da Esofagite Eosinofílica, suas etiologias, fisiopatologia e manifestações clínicas além de sua incidência e prevalência no Brasil. RESULTADOS: A partir das bases de dados Scielo, PubMed, Medline e BVS, foram identificados 26 estudos para a composição desta revisão de literatura, dos quais 17 foram incluídos para sua versão definitiva. CONCLUSÃO: A Esofagite Eosinofílica é uma doença em plena ascensão no Brasil, notoriamente subnotificada e que apresenta grande impacto na vida diária da comunidade. A partir de uma interação entre antígenos e o epitélio esofágico são desencadeados sintomas como a disfagia crônica, impactação alimentar e vômitos. Verificou-se ainda uma associação entre indivíduos atópicos e o maior desenvolvimento de Esofagite Eosinofílica. Por fim, a formulação de novas pesquisas sistemáticas e metanálises se fazem necessárias para promover um maior conhecimento da Esofagite Eosinofílica, a fim de subsidiar o arcabouço propedêutico dos médicos generalistas, sobretudo na atenção primária.
Prevalência do Transtorno Dismórfico corporal em pacientes candidatos e/ou submetidos a procedimentos estéticos na especialidade da cirurgia plástica: uma revisão sistemática
Authors: Rodrigues Luan Figueiredo , De Souza Junior Reinaldo Elias , Balbino Jamily Cardoso , Da Rocha Neto Luiz José , De Almeida Júlia Lemos Vilela , Silva Matheus Freitas , Oliveira Júlia Rocha , Campos Lucas de Souza , Bergamini Vitor Miguel , Sagata Yoshio , Guerreiro João Vitor Silva , Braga Marcelo de França e Azevedo , Maciel Gabriela Cordeiro , Pedro Gabriel Ferreira de Sena , Ferreira Bruna Alves , Lima Lara Vento Moreira , Pacheco Andressa Vitória Gomes , Aragão Tereza Madalena Mendes , Sampaio Rubem Rhuan Farias , Pascutti Paula Fernanda Greghi , Pina Guilherme Cristovam , Souza Gabriel Muniz Rodrigues , Cezario Isabella Franzon , De Almeida Laura Ferreira , da Silva Joyce Tavares , Moreira Bruna Iunes , Botelho Emanuelle Siqueira , Macêdo Eloah Nascimento , Jaime Alessandra , Jaime Adriano , Neves Tiemi Fukushima , Rizzo Luiz Fernando Ferreira , Lins Neto Leonardo D'Avila , Raffaelli Thereza Cozzolino Ferreira
Published: May 2023

O transtorno dismórfico corporal (TDC) é um transtorno psiquiátrico caracterizado pela preocupação excessiva e distorcida com a aparência física. Na especialidade da cirurgia plástica, é comum que pacientes busquem procedimentos estéticos para corrigir supostas imperfeições corporais decorrentes do TDC. O objetivo desta revisão sistemática é avaliar a prevalência do TDC em pacientes candidatos e/ou submetidos a procedimentos estéticos na especialidade da cirurgia plástica. Foram selecionados estudos que abordam a prevalência do TDC em pacientes submetidos a procedimentos estéticos, publicados entre 2010 e 2022. Os resultados indicam uma prevalência elevada de TDC em pacientes que buscam procedimentos estéticos na cirurgia plástica. A revisão também destaca a importância da avaliação psicológica pré-operatória e do tratamento adequado para pacientes com TDC ou outras condições mentais que possam interferir no resultado da cirurgia e na satisfação do paciente. Uma abordagem multidisciplinar envolvendo cirurgiões plásticos e profissionais de saúde mental é fundamental para garantir a segurança e a satisfação dos pacientes submetidos a procedimentos estéticos.
Alimentos plant based: análise da percepção do consumidor pelo uso de Word Association
Authors: De Camargos Flaviane Cristina , Carvalho Naiara Barbosa , Ribeiro Bruna Gabriele Silva , Muniz Ludmylla dos Santos , da Silva Vanelle Maria
Published: May 2023

Nos últimos anos, houve redução no consumo de produtos de origem animal, abrindo espaço no mercado para novos produtos formulados apenas com ingredientes vegetais. Esses produtos são denominados alimentos plant based, que se apresentam cada vez mais como opção nas dietas de pessoas que se identificam como veganas, vegetarianas ou flexitarianas. Neste contexto, torna-se imprescindível a compreensão dos direcionadores de mercado e do comportamento desse consumidor para assim explorar plenamente as oportunidades desse nicho. Diante do exposto, objetivando avaliar o perfil dos consumidores de alimentos plant based, bem como, a sua atitude e motivação frente a essa nova tendência alimentar, foi realizada uma pesquisa de mercado por meio da aplicação de questionário semiestruturado composto por 17 questões analisadas por estatística descritiva, tabulações cruzadas, teste qui-quadrado (α = 5%), análise de variância (ANOVA) e teste de Tukey, quando necessário, ambos ao nível de 5% de significância. Além disso, quatro imagens (estímulos) foram analisadas utilizando a metodologia de Word Association e análise de correspondência: Leite UHT Integral, Bebida vegetal, Bebida plant based e imagem de bebida vegetal com presença de selo da Sociedade Vegetariana Brasileira - SVB. Diante dos resultados obtidos é possível concluir que os consumidores de alimentos plant based são majoritariamente do sexo feminino (78,1%), composto por jovens adultos (59,2%) e solteiros (64,9%), identificam-se como vegetarianos (35,5%) e veganos (32,9%). Tais participantes são motivados por questões éticas (78,8%), ambientais (74,8%) e de saudabilidade (61,9%). São considerados importantes no ato de compra, o sabor (71,7%), preferindo aqueles alimentos que apresentem características semelhantes aos de origem animal, saudabilidade, sustentabilidade e o preço, que quando alto é identificado também como principal limitador ao consumo. A word association demonstrou que de forma geral, os produtos de origem animal são percebidos de forma negativa pelos respondentes. Além disso, não há diferença significativa entre as associações feitas a esses produtos denominados em língua nativa ou estrangeira, apesar de o uso de estrangeirismo estar fortemente ligado à falta de acessibilidade. Dessa forma, conclui-se que as empresas do nicho devem investir em pesquisa e desenvolvimento de produtos com qualidade sensorial semelhantes aos de origem animal, nomeados em português, com preço acessível, sendo facilmente encontrados no mercado. Além disso, a adesão a selos e certificações poderá resultar em grande diferencial competitivo no mercado.
Bioinspired Additive Manufacturing of Hierarchical Materials: From Biostructures to Functions
Authors: Wei Jingjiang , Pan Fei , Ping Hang , Yang Kun , Wang Yanqing , Wang Qingyuan , Fu Zhengyi
Published: May 2023

Throughout billions of years, biological systems have evolved sophisticated, multiscale hierarchical structures to adapt to changing environments. Biomaterials are synthesized under mild conditions through a bottom-up self-assembly process, utilizing substances from the surrounding environment, and meanwhile are regulated by genes and proteins. Additive manufacturing, which mimics this natural process, provides a promising approach to developing new materials with advantageous properties similar to natural biological materials. This review presents an overview of natural biomaterials, emphasizing their chemical and structural compositions at various scales, from the nanoscale to the macroscale, and the key mechanisms underlying their properties. Additionally, this review describes the designs, preparations, and applications of bioinspired multifunctional materials produced through additive manufacturing at different scales, including nano, micro, micro-macro, and macro levels. The review highlights the potential of bioinspired additive manufacturing to develop new functional materials and insights into future directions and prospects in this field. By summarizing the characteristics of natural biomaterials and their synthetic counterparts, this review inspires the development of new materials that can be utilized in various applications.
Biological activity of new organic germanium compounds
Authors:   Lipetsk State Pedagogical University named after P.P. Semyonov Tyan-Shansky, Solupaeva L.V.
Published: May 2023

The article provides information about the author’s own research. The data of numerous experiments carried out in different years indicate the revealed high biological activity of the class of original organogermanium compounds. The author presents data on studies at different levels of biological organization – from mitochondria of liver cells to the whole organism. A special place in the article is occupied by information about the possibility of correcting the pathogenesis of atherosclerosis with various organogermanium compounds. The methodological basis for interpreting the results is the theory of adaptation
Astragerm — activator of gene expression peroxisoms coactivator
Authors:   Lipetsk State Pedagogical University named after P.P. Semyonov-Tyan-Shansky, Solupaeva L.V. , Rybakov Y.L. , Gukasov V.M. , Myakinkova L.L. , Zhigacheva I.V. , Semyonova S.A. , Rasulov M.M.
Published: May 2023

The effect of the biologically active additive «Astragerm» on the activity of PGC-1-alpha was studied. The activating effect of astragerm on the expression of PGC-1-alpha in the «in vivo» system in rat muscle tissues was shown. Methods for quantitative assessment of mitochondria in tissues and analysis of the expression of genes included in the cascades of regulatory processes of energy metabolism were applied. Coordinated stimulation of tryptophanyl-tRNA synthetase gene expression, its non-canonical activity in the synthesis of the second messenger Ap3A, and expression of the PGC-1 alpha gene in «in vivo» systems under the action of astragerm was found, which indicates the unity of the mechanisms of energy regulation with the functions of protein synthesis and nonspecific immunity.
Detection and evaluation of breast pathology based on fuzzy clustering and discrete wavelet transform
Authors:   Siberian Federal University, Hamad Y.A. , Zotin A.G. , Simonov K.V. , Medievsky A.V. , Chizhova I.G. ,   Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky
Published: May 2023

The aim of the work is to develop a method for extracting a breast tumor and an uninfected area of the breast within the framework of medical imaging using a combination of fuzzy clustering with discrete wavelet transform (FCMDWT) tools. Two sets of mammographic breast image data were used in the study: a subset of breast images of a digital base mammography screening data (CBIS-DDSM) and private data set. Contrast enhancement techniques were used to improve image quality before using FCMDWT for tumor segmentation and analysis. To assess the accuracy of tumor isolation metrics such as the Dice coefficient (F1 score) and intersection by union (IoU) were used. The mean IoU was 98.41 and F1 score was 96.47 using the proposed FCMDWT.
ANALYSIS OF THE REAL CAPABILITIES OF THE OLDER PEOPLE THROUGH MONITORING WEB RESOURCES
Authors: Барышева Г.А. , Рождественская Е.М. , Хаперская А.В.
Published: May 2023

Проведен анализ реальных потребностей старшего поколения посредством мониторинга вебресурсов и выявления реальных запросов пользователей в сети интернет. В результате исследования была сформирована база данных, которая содержит систематизированные сведения о реальных потребностях старшего поколения. Выявлены направления для разработки социально-гуманитарных технологий улучшения благополучия старшего поколения на основе сравнения представлений об их реальных потребностях в научной литературе, государственной стратегии национальной политики и пользовательских веб-запросов. Авторами предложена следующая группировка реальных потребностей старшего поколения: 1) первичные потребности в финансовой помощи и медицинском уходе, социальной защите; 2) потребности в коммуникации, включая цифровую среду, и автономности проживания; 3) потребности в труде и саморазвитии; 4) потребности в самореализации. Предложены рекомендации по использованию результатов исследования в целях создания имитационной модели потребностей для мониторинга социально-экономических изменений в экономике старения и в режиме реального времени.

We analyzed the real capabilities for the older generation by monitoring web resources and identifying real user requests via the Internet. As a result, we formed a database containing dataset of the real capabilities for the older generation. We assume the directions to implement survey results in developing socio-humanitarian technologies for improving the well-being of the older people based on a comparison of ideas about their real needs in scientifi c literature, state strategy and user web requests. We propose a systematization of the real capabilities of the older people into the following groups: 1) primary needs for fi nancial assistance and medical care, social protection; 2) capabilities for communication, including the digital environment, and autonomy of residence; 3) capabilities for work and self-development; 4) the capability for self-realization. We proposed recommendations to create a simulation model of needs for monitoring socio-economic changes in the aging economy in real time.
ВЗАИМОСВЯЗЬ СЕМЕЙНОГО СОСТОЯНИЯ, ДУХОВНОСТИ, КАЧЕСТВА ЖИЗНИ И СЧАСТЬЯ У ПОЖИЛЫХ ЛЮДЕЙ В НИГЕРИИ
Authors: Oyinlola O. , Adebusoye L.A. , Cadmus E.O. , Afolayan O.K.
Published: May 2023

Happiness of older adults in rarely studied in the global south like Nigeria compared with the global north. This study assessed the relationship between family dynamics, spirituality, quality of life and happiness among older adults in Nigeria. Cross-sectional study of 378 older adults (≥60 years) were selected. Oxford Happiness questionnaire, the family dynamics, spirituality, and quality of life (QoL) were determined with the Family Relationship Index, spiritual Index of Well-being scale and Quality-of-Life Brief questionnaire respectively. Descriptive and inferential statistics were carried out at α0,05. The mean age was 72,8±7,1 years and 255 (67,5 %) were females. Majority 313 (82,8 %) were assessed to be happy. Overall, family dynamics, spirituality, and health related QoL were signifi cantly determinants of happiness (p<0,05). Among the women, there was good cohesion in the family dynamics (p=0,031), good health related QoL in the physical domain (p<0,001) and satisfaction with health (p=0,036) were the predictors of happiness. Having higher selfeffi cacy (p=0,018) and life scheme spirituality (p=0,050) were the predictors of happiness among the men. The present fi ndings showed that most of the older adults were happy. Routine assessment and interventions could increase the feeling of happiness among older adults in the global south.

Проблемы семейного состояния, духовности, качества жизни и счастья у пожилых людей редко изучают в южных странах, таких как Нигерия, по сравнению с северными. В этом исследовании оценивали взаимосвязь семейного состояния, духовности, качества жизни и счастья у пожилых людей в Нигерии. Было проведено поперечное обследование 378 пожилых людей (≥60 лет). Семейное состояние, духовность и качество жизни определяли с помощью индекса семейных отношений, шкалы духовного индекса благополучия и краткого опросника качества жизни соответственно. Описательную и логическую статистику проводили при α0,05. Средний возраст составил 72,8±7,1 года, 255 (67,5 %) были женщины. Большинство — 313 (82,8 %) пожилых были оценены как счастливые. В целом семейное состояние, духовность и качество жизни, связанное со здоровьем, были в значительной степени определяющими факторами счастья (p<0,05). У женщин предикторами счастья были семейная сплоченность (p=0,031), хорошее качество жизни, связанное с физическим здоровьем (p<0,001), и удовлетворенность здоровьем (p=0,036). Предикторами счастья у мужчин были высокая самореализация (р=0,018) и духовность жизни (р=0,050). Результаты исследования показали, что большинство пожилых людей были счастливы. Регулярная оценка и программы вмешательства для улучшения качества жизни могут повысить чувство счастья у пожилых людей южных стран.
ВЗАИМОСВЯЗЬ САМООЦЕНКИ И СУБЪЕКТИВНОЙ ЖИЗНЕСПОСОБНОСТИ У ПОЖИЛЫХ ЛЮДЕЙ В ИРАНЕ
Authors: Abolghaseminejad P. , Borhaninejad V. , Khanjani N. , Saber M. , Alizadeh S.
Published: May 2023

Today, aging of the population is considered one of the most fundamental challenges worldwide. One of the important factors in active aging is paying attention to psychological variables and related factors. This study was conducted aimed to determine the relationship between self-esteem and subjective vitality of the older people in Iran, Sirjan in 2020. In this descriptiveanalytical study, 200 older people aged 60 years and older were selected from comprehensive health centers in Sirjan by a two-stage random sampling method. The data were collected using the validated Rosenberg Self-Esteem Scale, and validated Subjective Vitality Scale. The data were analyzed using SPSS software version 20 using descriptive and inferential statistics, including the Mann—Whitney test, Kruskal—Wallis test, Post Hoc tests, and Spearman correlation coeffi cient. The mean age of the older people was 65,66±3,9 years. The the mean and standard deviation of self-esteem score was 36,34±4,62 and 21,80±2,85 for subjective vitality score. There was a positive and signifi cant correlation between self-esteem and subjective vitality R=0,58 (p<0,001). Also, gender, marital status and employment status were associated with subjective vitality (p<0,05). Therefore, planners and policymakers should consider self-esteem and subjective vitality in designing and prioritizing interventions related to improving the health of the older people.

Сегодня старение населения считается одной из самых фундаментальных проблем во всем мире. Одним из важных факторов активного старения является внимание к психологическим переменным и связанным с ними факторам. Это исследование было проведено для выявления взаимосвязи самооценки и субъективной жизнеспособности у пожилых людей в Сирджане (Иран) в 2020 г. Для этого описательноаналитического исследования были отобраны 200 пожилых людей 60 лет и старше из комплексных медицинских центров в Сирджане методом двухэтапной случайной выборки. Данные были собраны с использованием утвержденной шкалы самооценки Розенберга и утвержденной шкалы субъективной жизнеспособности. Данные были проанализированы с использованием программного обеспечения SPSS версии 20 с использованием описательной и логической статистики, включая критерий Манна— Уитни, критерий Крускала—Уоллиса, тесты Post Hoc и коэффициент корреляции Спирмена. Средний возраст пожилых людей составил 65,66±3,9 года. Среднее значение и стандартное отклонение самооценки составили 36,34±4,62 и 21,80±2,85 балла субъективной жизнеспособности. Выявлена положительная и достоверная корреляция самооценки и субъективной жизнеспособности R=0,58 (p<0,001). Также пол, семейное положение и статус занятости были связаны с субъективной жизнеспособностью (p<0,05). Таким образом, планировщики и политики должны учитывать самооценку и субъективную жизнеспособность при разработке и определении приоритетов вмешательств, связанных с улучшением здоровья пожилых людей.
COMBINATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ARTERIAL HYPERTENSION IN THE ELDERLY: CLINICAL AND HEMODYNAMIC FEATURES AND QUALITY OF LIFE
Authors: Таютина Т.В. , Клименко Н.Ю. , Лысенко А.В. , Казарян Т.М. , Модебадзе Е.В.
Published: May 2023

Проведена оценка особенностей клинической картины, гемодинамики и качества жизни пожилых пациентов с ХОБЛ и артериальной гипертензией. Полученные результаты позволяют говорить о том, что в случае сочетания этих патологий наблюдают не только отчетливые клинико-функциональные и гемодинамические изменения, но и снижение качества жизни, в значительной степени детерминированное выраженностью симптомов обоих заболеваний, а также тяжестью течения коморбидной патологии. Выявленные изменения у пожилых пациентов с ХОБЛ и артериальной гипертензией диктуют необходимость оптимизации, прежде всего, амбулаторного этапа наблюдения и реабилитации пожилых пациентов с коморбидной патологией.

Clinical features, hemodynamics and quality of life of elderly patients with a combination of chronic obstructive pulmonary disease and arterial hypertension were assessed. The results of the study suggest that in the case of a combination of arterial hypertension and chronic lung disease, not only distinct clinical, functional and hemodynamic changes are observed, but also a signifi cant decrease in the quality of life, largely determined by the severity of the symptoms of both diseases, as well as the severity of the comorbid pathology. The revealed changes in elderly patients with chronic obstructive pulmonary disease and arterial hypertension dictate the need to optimize, fi rst of all, the outpatient stage of observation and rehabilitation of elderly patients with comorbid pathology.
PHYSICAL REHABILITATION FOR ANKLE JOINT INJURIES IN ELDERLY AND SENILE PEOPLE (STAGE 2)
Authors: Бобунов Д.Н. , Селезнева Д.Д. , Абдульминова Р.И. , Шихирина А.А. , Хацукова К.С. , Шапанов Р.А. , Погодина Я.В. , Иорданишвили А.К. , Арутюнов В.А.
Published: May 2023

Основная часть повреждений у пациентов пожилого и старческого возраста в результате повышенной физической нагрузки при движении приходится на нижние конечности. Травмы голеностопного сустава имеют многофакторную этиологию, включающую взаимодействие компенсаторной биомеханики позвоночного столба и ног, внешних факторов среды и выбора обуви. В связи с этим необходим комплекс реабилитационных мер, включающий ЛФК, для осуществления восстановительного процесса не только в амбулаторных условиях, но и на дому, тем самым улучшая качество жизни и предотвращая инвалидизацию. Пациенты группы сравнения получали стандартную комплексную терапию, включающую ортопедические методы, медикаменты, миостимуляцию, массаж. Пациентам основной группы дополнительно к традиционной схеме реабилитации была добавлена методика ЛФК по заявленному способу. В ходе исследования не выявлено значимых осложнений и побочных эффектов при использовании данной методики, что позволяет рекомендовать ее как средство вторичной профилактики травм голеностопного сустава и стопы, особенно при противопоказаниях к консервативной и таргетной терапии. Выявлена существенная разница по показателям гониометрии после восстановительного периода у больных основной и группы сравнения.

The main part of the injuries of elderly and senile patients as a result of physical activity falls on the lower limbs, due to the increased load during movement. Ankle injuries have a multifactorial etiology involving the interaction of compensatory spinal and leg biomechanics, environmental factors, and shoe selection. In this regard, it is necessary to prepare a complex of rehabilitation measures, including physical therapy, with the possibility of implementing the recovery process not only on an outpatient basis, but also at home, thereby improving the quality of life and preventing disability. The patients of the comparison group received standard complex therapy, including orthopedic methods of treatment, drug therapy, myostimulation, and massage. For patients of the main group, in addition to the traditional complex, the exercise therapy technique according to the claimed method was added. The study revealed no signifi cant complications and side effects when using this technique, which allows us to recommend it as a means of secondary prevention and injuries of the ankle joint, especially when conservative and targeted therapy is contraindicated. A significant difference was found in goniometry parameters after the recovery period in patients in the main and comparison groups.
Proyecto de innovación docente CIRCE. Recorrido virtual 1: el proyecto de ejecución.
Authors: Rivera Gómez Carlos Alberto , Roa Fernández Jorge , Diz Mellado Eduardo María , López Cabeza Victoria Patricia , Galán Marín María del Carmen
Published: May 2023

El recurso consiste en un recorrido virtual durante diversas fases de ejecución del proyecto de construcción de una vivienda unifamiliar. A lo largo del recorrido es posible mejorar la información del proceso con narraciones específicas y archivos de documentación escrita y gráfica complementaria con objeto de posibilitar un acercamiento gradual a las sucesivas fases desde el proceso de ideación y diseño hasta la concreción y detalle del proyecto de ejecución. En este primer recorrido de una serie de dos, se introducen los conceptos relativos a la documentación y especificaciones del Proyecto de Ejecución ilustrados mediante su concreción en una vivienda real que funciona como caso de análisis específico.

El recurso se implementará fundamentalmente en los procesos de formación de los diferentes agentes, especialmente técnicos, implicados en procesos edificatorios y constructivos según la Ley de Ordenación de la Edificación. Específicamente se entiende de especial utilidad para la formación de estudiantes de arquitectura ya que posibilita un acercamiento más directo a la realidad profesional constructiva. Se considera aplicable a la docencia de asignaturas del área de Construcciones Arquitectónicas y, específicamente, a los contenidos de la asignatura Construcción 6.

En el ámbito universitario técnico-arquitectónico, teniendo en consideración los múltiples inconvenientes para el traslado físico de los estudiantes a localizaciones donde se verifican los procesos de construcción de edificios, el uso de distintos recursos audiovisuales, y en especial de la realidades virtuales y mixtas, suponen una alternativa adecuada de virtualizar dichas visitas.

Además de su utilidad en la formación de estudiantes en otros grados diferentes al del Fundamentos de Arquitectura, el recurso puede servir de base para la formación en otros niveles educativos y como material didáctico para la impartición de cursos de personal técnico vinculado a la construcción de edificios.

Este recurso pretende mejorar la comprensión de conceptos y procesos con un grado de complejidad considerable incluso en la formación universitaria de profesionales vinculados a la Arquitectura mediante la aproximación de los estudiantes a un caso real que, por su singularidad e interés proyectual y técnico-constructivo, facilite ese proceso de aprendizaje y mejore la adquisición de las competencias profesionales requeridas tanto para la redacción del Proyecto de Ejecución como del proceso de Dirección de Obras.
Caracterización de genotipos del virus del papiloma humano en mujeres que acuden a la Unidad de Atención Integral del VIH e Infecciones Crónicas de un hospital guatemalteco
Authors: Pereira Rocío , Navas-Castillo Jessenia , Samayoa-Bran Ana
Published: May 2023

La infección por VIH suprime el sistema inmune al aumentar el riesgo de adquirir una infección por un virus del papiloma humano de alto riesgo (VPH-AR), la persistencia y, en último caso, el desarrollo de cáncer de cérvix. Objetivo: Caracterizar los genotipos del VPH, describir las características sociodemográficas y epidemiológicas, y establecer la asociación entre el VPH y las variables clínicas de monitoreo en las mujeres VIH positivo que acudieron a la UAI-HR de marzo de 2019 a agosto de 2021. Método: Investigación descriptiva-transversal retrospectiva en 406 mujeres con VIH. Se llevó a cabo un muestreo no probabilístico de casos consecutivos; los datos fueron analizados en el software Jamovi, mediante el cálculo de frecuencias y porcentajes para variables categóricas y a través de tablas de contingencia, empleando la prueba de chi cuadrado. Resultados: Se encontró una frecuencia de genotipos del VPH-AR de 36.95% (150/406), predominando otros VPH-AR (95, 76.0%). El rango de edad que más se presentó (58, 39.5%) fue de 30 a 39 años. La mayor frecuencia de positividad para genotipos de VPH-AR fue en pacientes con recuentos mayores a 500 células/ µL (30.6%, 66) y con cargas virales del VIH indetectables (28.3%,53). Conclusión: La frecuencia de genotipos del VPH-AR evidencia la importancia de realizar el tamizaje para el mismo en las pacientes de diagnóstico reciente del VIH, así como la búsqueda periódica del VPH a toda mujer negativa en su primera prueba.
A STUDY OF BRANCHING PATTERN OF EXTERNAL CAROTID ARTERY IN THE CAROTID TRIANGLE – A CADAVERIC STUDY
Authors: Balaiya Anitha , Shanmugum Shanthini
Published: May 2023

Background Carotid triangle is an important neurovascular area located in the anterior cervical region of the neck.
Variations in the external carotid artery in carotid triangle may complicate surgeries like radical neck dissection,
aneurysm repair in the carotid triangle To study the branching pattern and variations of external c Aim and Objective arotid artery in carotid
triangle This study includes 30 formalin xed cadavers from the Department of Ana Method tomy, Sri lakshmi Narayana institute of medical
sciences Puducherry . This study includes all the cadavers during routine anatomical dissection by the students. In this present study Results
both sides of the neck regions , a total of 60 sides were dissected. External carotid artery branches in the carotid triangle were traced. In the study
period we found 3% of superior thyroid artery arising from common carotid artery and common unilateral linguofacial trunk in 6% of cadavers.
Other branches of external carotid artery in the carotid triangle were traced. Ca Discussion And Conclusion rotid triangle is a vascular area
contains common carotid artery and its terminal branches, important area for auscultation and palpation of vessels. With in the carotid triangle
common carotid artery divides into internal and external carotid arteries at the level of upper border of thyroid cartilage. External carotid artery
gives eight branches with in this ve branches arises from carotid triangle. The study of branches of external carotid artery in the carotid triangle
was paramount important to avoid iatrogenic injury during neck dissection.
IMPACT OF TECHNOLOGY ON SOCIAL AND COGNITIVE DEVELOPMENT IN CHILDREN
Authors: Maria Joy Rani
Published: May 2023

Technology has inuenced children's social and cognitive development in recent years. This article explores both the
positive and negative impacts of technology on children's social and cognitive development. On the one hand, technology
can provide children with the opportunity to learn and engage in activities that may not be available in their home environment. This can lead to
increased condence and improved problem-solving skills. On the other hand, technology can lead to a decrease in physical activity, an increase in
feelings of isolation and loneliness, an over-dependence on technology, and a decrease in creativity and problem-solving skills. The article also
discusses technology's potential implications on children's social and cognitive development. It looks at how technology can both positively and
negatively affect children's development. It also looks at how it can be used to help them grow and develop healthily. Ultimately, this article
provides insight into the impact of technology on children's social and cognitive development and the potential implications of technology on
their lives
SILICONE RELINING OF MAXILLARY HOLLOW OBTURATOR TO ACCOMMODATE FOR CHANGE IN ORO-NASAL DEFECT ANATOMY – A CASE REPORT
Authors: Lenka Lipika , Acharya Anaida , Kumar Patro Tapan , Dhal Angurbala , Garhnayak Lokanath , Kumar Ullash
Published: May 2023

Oral cancer constitutes 1/3rd of all human cancers and it's the 6th most occurring cancer worldwide. Maxillary neoplasm
is mostly treated by surgical resection of the maxilla and adjoining structures. The ablative surgery frequently results in
communication between oral and nasal cavities, this causes functional impairment of speech and swallowing which can be treated either by
reconstructive surgery or rehabilitation with an obturator prosthesis. Though reconstructive surgery offers better patient comfort, it is not possible
in many situations particularly when the defect is large and when there is a need for radiation therapy.
Obturator is the primary method of rehabilitating larger maxillary defects. Numerous techniques of hollow bulb fabrication have been mentioned
in the literature from time to time to improve the resonance of speech and to reduce the weight of the prosthesis. In this case report a direct
investment method of waxed-up closed hollow bulb obturator is used. And silicone relining of the obturator was done to improve the patient's
comfort and accommodate for the change in oro-nasal defect size
STUDY ON DRUG PRESCRIPTION PATTERNS AMONG DENGUE PATIENTS IN A TERTIARY CARE HOSPITAL, TUMKUR
Authors: K Naveen , S Vathsala
Published: May 2023

Background: Dengue fever causes a signicant economic and social burden on the population worldwide. When
standard management guidelines are not practiced it leads to economic burden on patients. The present study aims to
assess the drug prescription pattern for dengue patients admitted in a tertiary care teaching hospital. A prospective study Material and Methods:
was conductedamong 100 dengue patients undergoing treatment in the Department of General Medicine of Medical college in Tumakuru,
Karnataka over a period of one year from November 2018 to October 2019. Details of drugs prescribed was documented and analysed. Results:
The mean age of patients was 34.25 ± 14.69 years with minimum and maximum age of 14 and 68 years respectively. 56% of patients were male
and 44% female.The average number of drugs prescribed per patients in the present study was 3.7 ± 1.05 drugs. A total of 110 antimicrobial were
used with 24% and 41% receiving two and one antimicrobial agents respectively for treating dengue patients. All patients were given i.v. uids
and antipyretrics. Cari papaya extract was given to 48% of cases. Steroids were needed only among 3% of dengue cases while platelet transfusion
was done for 29 patients with mean requirement of 6.79 ± 2.4 units of platelet. Si Conclusion: gnicant proportion of patients received antibiotics
and other drugs with no proven benets in dengue management, increasing the cost of treatment and unnecessary side-effects. There is a need to
conduct training programme among treating physician on the use of recommended drugs as per standards.
PROSPECTIVE STUDY OF BURST ABDOMEN AND VARIOUS DETERMINANTS
Authors: G.D Yadav , Yadav Anju , Saxena Nishant , Pratap Singh Gajendra
Published: May 2023

Background: Wound dehiscence/burst abdomen is a serious postoperative complication with incidence of 10.0-30.0%,
and is of great concern because of risk of evisceration, the need for immediate intervention, and the possibility of repeat
dehiscence, higher risk in elderly age group and surgical wound infection. Despite progress made in peri-operative and postoperative care over
the past few years, wound dehiscence after abdominal surgery continues to be a challenging complication, which considerably prolongs hospital
stay(morbidity) and is associated with mortality rates of 10% to 44%. Wound dehiscence carries with it a list of multiple etiological factors that
need evaluation and early intervention to decrease morbidity and mortality. To nd AIM: various aetiology/risk factors of burst abdomen in
patients, admitted in surgical emergency department of LLR hospital, Kanpur T MATERIALS AND METHODS: his is a prospective study, in
which 80 patients of burst abdomen aged more than 18years were studied, which underwent exploratory laparotomies in Department of General
surgery, LLR & Associated Hospitals, G.S.V.M. Medical College from January 2021 to October 2022. Various etiological factors were observed
like age, sex, post operative discharge, surgical site infection and patients undergoing emergency/elective exploratory laparotomy, aged more
than 18 years and primarily operated in Department of General surgery, LLR & Associated Hospitals, G.S.V.M. Medical College and giving
consent. CONCLUSION: Burst abdomen is a serious sequel of impaired wound healing and our ndings were as follows:- Mean age group of
presentation was 47.25+ 8.95 years., male preponderance of 76.25% with respect to female of 23.575%, burst abdomen present in 80 cases of
emergency laparotomy and none in elective cases, on the basis of discharge 75% cases were having sero sanguineous discharge, the organism
most commonly isolated from stitch line was gram negative bacteria i.e. E coli (45%).
PREDICTABLE FACIAL ESTHETICS BY PRESURGICAL NASOALVEOLAR MOULDING IN NEONATES - A CASE REPORT
Authors: Pattanaik Sweta , Sahoo Jyotirmayee , Kumar Patro Tapan , Dhal Angurbala , Garhnayak Lokanath
Published: May 2023

A Cleft is a congenital abnormal space or gap in the upper lip and palate. Although plastic surgery has made great
advances in the area of cleft surgery, aesthetical corrections of the decient columella and nasal cartilages were difcult.
presurgical naso-alveolar molding (PNAM) at an early stage is used to reduce soft tissue and cartilaginous deformity. This article presents a case
report of a 6-day-old baby boy with a left-sided unilateral incomplete cleft lip and palate, with no signicant medical history or any associated
systemic illness. He was referred with the primary need for a feeder plate. The width of the cleft was measured from the base of the alveolus on one
side to the other and was approximately 7 mm. The nal impression was made with a custom tray. NAM appliance was fabricated and inserted in
the patient's mouth. Orthodontic wire of 21 gauzes was used for wire bending to support the acrylic forming a nasal bulb. In 2 months, the followup patient was recalled at each 15 days intervals for 1 and a half months for activation and modication of the plate to gradually approximate the
alveolar segments. After 2 months of follow-up, it was shown that the cleft palate gap was reduced to 3mm from 7mm. PNAM allows overall
improvement in the aesthetics of nasolabial complex in cleft conditions and minimizes the extent and the numbers of surgery. The cleft deformity
was signicantly reduced in size with the NAM therapy in the present case
ADVANCES IN DENTAL VENEERS: A REVIEW
Authors: Virendra Gaonkar Akanksha , Gopeshetti Pallavi , Pujar Madhu , Umesh Sahana , Chowdary Anjany
Published: May 2023

Veneers have made a breakthrough in dentistry in recent times. They have been predicted to increase a patient's selfcondence, personal relationship, and even success in his or her career. Hence, with veneers, it is possible to create
amazing esthetic results and yet retain a considerable amount of tooth structure. Successful results depend not only on the clinical and laboratory
technique used for the assembly of veneers but also on an understanding of the scientic background behind its material aspect and case selection.
Veneers have evolved in the past 10 years or so in the material aspect. Various materials are used to fabricate veneers like composite, processed
composite, porcelain, ceramic, preformed acrylic laminates, and glass-ceramic veneers. The current article is a review that illustrates recent
advancements in the material aspect of dental veneers.
VISUAL OUTCOME AND INTRA AND POST-OPERATIVE COMPLICATIONS IN POSTERIOR POLAR CATARACT PATIENTS FOLLOWING PHACOEMULSIFICATION IN TERTIARY EYE CARE HOSPITAL IN ELURU.
Authors: Harinath Mamidi , Vivekanand Undrakonda
Published: May 2023

Aim And Objective: To evaluate the visual outcome, intra and post-operative complications of posterior polar cataract following phacoemulsication. Department of ophthalmology, Alluri sitaramaraju academy Setting: of medical sciences, Malkapuram, Eluru, Andhra Pradesh, india-5343005. A Prospective longitudinal study in which Phacoemulsication s Methods and materials: urgery was carried out in 40 posterior polar cataract patients under local anaesthesia by single surgeon with age ranging from 31 to 65years after taking informed and written consent, duration of study is 18 months all data were analyzed by using Microsoft e Statistical Analysis: xcel sheet using descriptive statistics Results: out of 40 cases, posterior capsular tear occured in 5 eyes (12.5%), capsular bag IOLs was achieved in 35cases sulcus-sulcus in 5 cases, post-operative visual outcomes at day 7 is 6/18(35%) and 6/24(22.5%) , at 1st month visual outcome is improved to 6/9(42.5%) and 6/12(30%) at 6th month visual acuity is 6/6 in 10%, 6/9 in 47.5%(19) and 6/12(32.5%). posterior polar cataracts Conclusion: can be safely removed,If the proper surgical approach is used. In the majority of instances, visual acuity dramatically improved, despite the fact that some patients with a unilateral cataract had already experienced amblyopia and proper patient pre op work-up and patient counselling is needed.
A CASE OF SPINAL ABSCESSES IN A POORLY CONTROLLED DIABETIC PATIENT
Authors: Pereira Jessica , Kolwalkar Ravish , Dubhashi Avinash
Published: May 2023

This is a case report of a poorly controlled diabetic patient who presented with high grade fever and back pain. He was found to have epidural and
paraspinal abscesses. The abscesses were drained and antibiotics were given as per culture sensitivity and the patient showed a good response to the
same.