bluuebunny/crossref_metadata_2025 huggingface dataset:
The demand of cancer patients to anticipate the management of undernutrition: is a nutrition prehabilitation before treatment conceivable as supportive care to improve quality of life? Argument for the NEHOTEL® concept
Authors: Philippe Pouillart , Flore Dépeint , Isabelle Soula , Bruno Raynard
Published: February 2024

Purpose

Our translational research team in nutrition and cancer works to identify changes in eating and cooking behaviors since the diagnosis. Educational tools have been standardized as supportive care workshops in culinary practice and nutrition to enhance quality of life with regards to symptoms associated with treatment. Ongoing work with a cluster of expert patients led to the conclusion that such tools are essential but may be addressed too late, once symptoms are present and undernutrition is set. We thus investigated the concept of an early nutritional and multimodal prehabilitation program to improve quality of life.

Methods

Over a period of one year, 10 patients, together with researchers and caregivers co-constructed the NEHOTEL educational program. The relevance of this program was then confronted to the practical, medical and ethical points of view.

Results

An innovative multimodal supportive care 5-days course has been validated with our panel of expert patients. In this setting, new cancer patients will be invited to a non-medical hotel facility specifically designed for this project.

Conclusions

In the synopsis of the cancer care path as currently conceived in France, the early positioning of this intervention, which formalizes the need for unmet supportive care of patients in nutrition, raises questions about its medico-technical feasibility and the chances of visualizing a benefit on the quality of life. NEHOTEL® concept design is the outcome of this translational work, supported by an ongoing clinical feasibility study.
High-throughput nano-flow proteomics using a dual-column electrospray source
Authors: Staes An , Boucher Katie , Dufour Sara , Maia Teresa Mendes , Timmerman Evy , Van Haver Delphi , Pauwels Jarne , Demol Hans , Vandenbussche Jonathan , Impens Francis , Devos Simon
Published: February 2024

With current trends in proteomics, especially regarding clinical and low input (to single cell) samples, it is increasingly important to both maximize the throughput of the analysis and maintain as much sensitivity as possible. The new generation of mass spectrometers (MS) are taking a huge leap in sensitivity, allowing to analyze samples with shorter liquid chromatography (LC) methods while digging as deep in the proteome. However, the throughput can be doubled by implementing a dual column nano-LC-MS configuration. For this purpose, we used a dual-column setup with a two-outlet electrospray source, and compared it to a classic dual-column setup with a single-outlet source.
The regulatory network of the White Collar complex during early mushroom development inSchizophyllum commune
Authors: Vonk Peter Jan , van der Poel Marieke J. P. , Niemeijer Zoé E. , Ohm Robin A.
Published: February 2024

Blue light is an important signal for fungal development and is detected by the White Collar complex, which consists of WC-1 and WC-2. Most of our knowledge on this complex is derived from the ascomyceteNeurospora crassa, where both WC-1 and WC-2 contain GATA zinc-finger transcription factor domains. In basidiomycetes, WC-1 is truncated and does not contain a transcription factor domain, but both WC-1 and WC-2 are still important for development . In the model mushroomSchizophyllum commune, we show that dimerization of WC-1 and WC-2 happens independent of light, but that induction by light is required for promoter binding by the White Collar complex. Furthermore, the White Collar complex is a promoter of transcription, but binding of the complex alone is not always sufficient to initiate transcription. For its function, the White Collar complex associates directly with the promoters of structural genes involved in mushroom development, like hydrophobins, but also promotes the expression of other transcription factors that play a role in mushroom development.
The impact of management practices on export margins of firms: evidence from a recent Egyptian industrial survey
Authors: Kamal Yasmine
Published: February 2024

Purpose

The paper aims at studying the effect of management practices on the extensive and intensive export margins of Egyptian manufacturing firms.

Design/methodology/approach

The study relies on the 2020/2021 Egyptian Industrial Firm Behavior Survey (EIFBS) which comprises 2,383 manufacturing firms representing small, medium, and large sized firms located in different regions of Egypt: Urban Governorates, Lower Egypt, and Upper Egypt. It constructs an overall management z score for each firm to estimate its effect on a firm’s probability of exporting and value of exports using Ordinary Least Squares (OLS) regressions.

Findings

Results indicate that good management is associated with a higher probability of firm exporting as well as higher export revenues conditional on exporting, robust to controlling for the level of domestic sales. These effects do not differ by firm ownership or type of sector, but rather by firm size, with managerial competence raising the probability of exporting more for large-sized firms. Additionally, good management is associated with higher firm productivity, innovation and worker training propensities which gives evidence that it is both an efficiency and a quality enhancer. Moreover, monitoring and targeting practices have significant positive effects on both margins, while incentives are only significant for the extensive margin.

Practical implications

Firms that aim at enhancing their export prospects and revenues should devote resources to review and upgrade their management systems to boost their product quality and production efficiency. Policy-wise, the government should create a competitive market environment that is open to both domestic and foreign firms’ entry to stimulate the adoption of better management practices.

Originality/value

The paper is the first to explore the link between firm management practices and export outcomes for a MENA country (Egypt). It makes use of a recent survey, the 2020/2021 Egyptian Industrial Firm Behavior Survey (EIFBS). The findings shed light on the importance of different management components (monitoring, targeting and incentives) in driving a manufacturing firm’s export performance.
Numerical modelling of heating and melting of metal in a mini industrial direct current electrical arc furnace
Authors: Pavlovs Sergejs , Jakovičs Andris , Chudnovsky Alexander
Published: February 2024

Purpose

The purpose of this paper is the study of the electro-vortex flow (EVF) as well as heating and melting processes for mini industrial direct current electric arc furnace (DC EAF).

Design/methodology/approach

A mini DC EAF was designed, manufactured and installed to study the industrial processes of heating and melting a small amount of melt, being 4.6 kg of steel in the case under study. Numerical modelling of metal melting was performed using the enthalpy and porosity approach at equal values and non-equal values of the solidus and liquidus temperatures of the metal. The EVF of the liquid phase of metal was computed using the large eddy simulation model of turbulence. Melt temperature measurements were made using an infrared camera and a probe with a thermocouple sensor. The melt speed was estimated by observing the movement of particles at the top surface of melt.

Findings

The thermal flux for metal heating and melting, which is supplied through an arc spot at the top surface of metal, is estimated using the thermal balance of the furnace at melting point. The melting time was estimated using numerical modelling of heating and melting of metal. The process started at room temperature and finished once whole volume of metal was molten. The evolution of the solid/melt phase boundary as well as evolution of EVF patterns of the melt was studied.

Originality/value

Numerical studies of heating and melting processes in metal were performed in the case of intensive liquid phase turbulent circulation due to the Lorentz force in the melt, which results from the interaction of electrical current with a self-magnetic field.
How a leader in the footsteps of Atatürk enlightened the lives of thousands of children
Authors: Ünsal Efe
Published: February 2024

Learning outcomes

The key learning from this case study include the following: first, there are various leadership types that leaders can exhibit, such as servant leadership and transformational leadership, and an individual’s leadership style can be evaluated by analysing his/her traits and behaviours. Second, decision-making is much more critical for leaders than for anyone else, and there are different approaches, such as rational and intuitive decision-making, that leaders can apply when making a decision. Third, in male-dominated work environments such as the sports sector, female executives should carefully weigh the risks and opportunities of leadership positions while being promoted.

Case overview/synopsis

The UPS Sports and Culture Club was founded in 2003 by Haluk Ündeğer in Zeytinburnu district, one of the most dangerous neighbourhoods in Istanbul that had a bad reputation for being high on crime and drugs. The club’s main goal was to train children from disadvantaged groups to develop a career in sports. Shortly after the club’s founding, Semra Demirer, a physical education teacher who had devoted her life to children’s physical, cultural and personal development, crossed paths with the UPS Club. In 2004, Demirer started to work at the UPS Sports and Culture Club as the general coordinator. She played an important role in the growth and development of many children over the years and helped raise very talented athletes such as Simge Aköz. In 2020, on the heels of financial and administrative difficulties, the club was at the risk of being shut down. Hence, Demirer grappled with the decision of whether to share this information with the employees and players in the club. She deeply considered how she could overcome the conflict between transparency and confidentiality she was experiencing.

Complexity academic level

The case study is suitable for undergraduate students.

Supplementary materials

Teaching notes are available for educators only.

Subject code

CSS 6: Human Resource Management.
Organizational learning, quality and safety culture in patient care: comparing Colombia and the Kingdom of Saudi Arabia
Authors: Santa Ricardo , Morante Diego , Tegethoff Thomas , Berggrun Luis
Published: February 2024

Purpose

The purpose of this study is to determine the interactions between factors such as organizational learning, feedback about errors, punitive response to errors and communication quality in hospitals in the Kingdom of Saudi Arabia and Colombia when adopting a culture of quality and safety (CQS) in patient care.

Design/methodology/approach

Based on a literature review, a self-administered questionnaire was developed and used to collect data from 417 Saudi respondents affiliated with hospitals and 483 Colombian respondents at the beginning of the pandemic. Structural equation modeling is used in this study to test the hypothesized relationships.

Findings

The results show a solid and significant predictive relationship between feedback about errors and the CQS in both countries (Colombia: b = 0.55, p < 0.001; KSA: b = 0.44, p < 0.001), but a very low and insignificant predictive relationship between no punitive response to errors and CQS (Colombia: b = –0.02, p > 0.05; KSA: b = 0.05, p > 0.05).

Practical implications

This study demonstrates the importance of organizational learning in fostering a CQS in the health-care sector in the Kingdom of Saudi Arabia and Colombia. Recent unprecedented policy actions motivated by the COVID-19 pandemic, such as social distancing, lockdowns and safety practices enforcement, have further highlighted this concern. Moreover, attention to the dimensions addressed in this study is required for accreditation purposes in organizations seeking to promote a CQS. Overall, this research highlights the vital role of safety and quality practices among health-care organizations, which has significant policy implications, especially in the current period of high uncertainty.

Originality/value

This paper contributes to the theory and practice in the health-care sector by extending the current knowledge of the impact of the quality of communications, non-punitive response to errors and feedback about errors in organizational learning and safety culture, and by presenting a novel, quantitative methodology seldom used for these topics.
Reinforcing infrastructure equity through leveraging Envision rating system within construction education
Authors: Rahat Rubaya , Calle Müller Claudia , ElZomor Mohamed
Published: February 2024

Purpose

Construction education rarely addressed the importance of disseminating knowledge on infrastructure equity, thus impeding progress toward creating equitable and sustainable developments. This study aims to investigate the existing sustainability courses under the American Council for Construction Education (ACCE) accredited construction management (CM) programs to examine the integration of infrastructure equity topics and assess improvement in CM students’ knowledge and awareness to address this issue through an intervention.

Design/methodology/approach

To achieve these objectives, this research reviewed the sustainability course descriptions of the ACCE-accredited undergraduate and graduate CM curricula. Furthermore, the study implemented a workshop within a CM sustainability course that taught the students about the key concepts of infrastructure equity as well as how to address this issue by leveraging the Envision infrastructure rating system.

Findings

The course review results showed that most sustainability courses lack topics such as infrastructure equity and social sustainability. Moreover, the analysis of pre- and postworkshop surveys indicated that guided training could improve the students’ understanding as well as boost their confidence to address and mitigate infrastructure inequity issues.

Originality/value

The findings of the study are valuable for increasing awareness of infrastructure equity and facilitating the future construction workforce with the required expertise to develop equitable infrastructure systems.
Validating two shortened versions of the fitness switching cost scale
Authors: Kim Kyungyeol , Lee Senyung
Published: February 2024

Purpose

Although the fitness switching costs scale (FSCS) was shown to have sound psychometric properties, the length of the 54-item may impose burdens on survey participants and present methodological and analytic challenges for researchers and practitioners. Therefore, the present study shortened and validated two versions of the FSCS, namely the 33-item FSCS (FSCS-33) and the 11-item FSCS (FSCS-11).

Design/methodology/approach

In Study 1 (n = 411), the most useful items from the FSCS for the FSCS-33 and FSCS-11 were identified using item response theory (IRT). Study 2 (n = 391) and Study 3 (n = 400) assessed the psychometric properties of the FSCS-33 and FSCS-11, respectively, using partial least squares structural equation modeling.

Findings

The FSCS-33 and FSCS-11 demonstrated strong reliability and validity in assessing switching costs in fitness centers.

Originality/value

The psychometrically sound short-form scales provide researchers and practitioners with convenient and accurate means of measuring switching costs in fitness centers.
Cannabis sativa (hemp) – an eco-friendly material for heritage conservation and sustainable environment
Authors: Singh Manager Rajdeo , Kanth Aditya Prakash , Sawant Madhuri , Ragde Rajesh
Published: February 2024

Purpose

The present work highlights the outstanding properties of Cannabis sativa that can be harnessed for various utilitarian functions and its climate friendly properties.

Design/methodology/approach

In this paper, the authors reviewed current research on all possible utilities from household work to manufacturing of various products that are environmentally sustainable. The authors have presented some of their research on this materials and also exploration of hemp as an archaeological material based on the findings from wall paintings of Ellora caves.

Findings

There are references of hemp use in mixing with earthen/lime plaster of western Indian monuments. Around 1,500 years of Ellora’s earthen plaster, despite harsh climatic conditions, survived due to the presence of hemp in the plaster that adds durability, fibrosity and its capacity to ward off insects and control humidity. Furthermore, the outstanding quality of Cannabis as carbon sequestrant was harnessed by Indians of ancient times in Ellora mural paintings.

Research limitations/implications

This work discusses some relevant literature on the potential use of hempcrete aligned with Agenda 2030 of sustainable development goals.

Practical implications

There are several research going on in producing sustainable materials using hemp that have the least environmental impact and can provide eco-friendly solutions.

Social implications

The authors impress upon the readers about multifarious utility of the hemp and advices for exploration of this material to address many environmental issues.

Originality/value

This paper presents both review of the existing papers and some components coming directly from their laboratory investigations.
Psychologically gaining through losing: a metaphor analysis
Authors: Du Plessis Linda , Bui Hong T.M.
Published: February 2024

Purpose

This paper conceptualises how managers psychologically experience and respond to crises via metaphor analysis.

Design/methodology/approach

This paper uses a discourse dynamics approach to metaphor analysis. Conceptual metaphors were analysed and developed into concept maps through 37 semi-structured interviews with senior managers from different portfolios within 16 public universities in South Africa after #FeesMustFall protests.

Findings

Five domains emerged, including (1) looming crisis, (2) crisis onset, (3) crisis triage and containment, (4) (not) taking action and (5) post-crisis reflection. These domains shape a framework for the crisis adaptation cycle.

Practical implications

This study suggests that organisations should pay more attention to understanding emotions in crises and can use the adaptation model to develop their managers. It shows how metaphors can help explain affective and cognitive experiences and how emotions shift and evolve during a crisis. Managers should be aware of early signs of the crisis and its potential impact on their business operation in the looming and recognition stages, analyse the situation and work collectively on possible actions to minimise losses and maximise gains.

Originality/value

This is a rare investigation into the emotions of senior managers in the public sector in a social movement and national crisis via unconventional research methods to advance cognitive appraisal theory in crisis management.
Prescriptive digital transformation maturity model: a development and validation study
Authors: Kocaoglu Batuhan , Kirmizi Mehmet
Published: February 2024

Purpose

This study aims to develop a modular and prescriptive digital transformation maturity model whose constituent elements have conceptual integrity as well as reveal the priority weights of maturity model components.

Design/methodology/approach

A literature review with a concept-centric analysis enlightens the characteristics of constituent parts and reveals the gaps for each component. Therefore, the interdependency network among model dimensions and priority weights are identified using decision-making trial and evaluation laboratory (DEMATEL)-based analytic network process (ANP) method, including 19 industrial experts, and the results are robustly validated with three different analyses. Finally, the applicability of the developed maturity model and the constituent elements are validated in the context of the manufacturing industry with two case applications through a strict protocol.

Findings

Results obtained from DEMATEL-based ANP suggest that smart processes with a priority weight of 17.91% are the most important subdimension for reaching higher digital maturity. Customer integration and value, with a priority weight of 17.30%, is the second most important subdimension and talented employee, with 16.24%, is the third most important subdimension.

Research limitations/implications

The developed maturity model enables companies to make factual assessments with specially designed measurement instrument including incrementally evolved questions, prioritize action fields and investment strategies according to maturity index calculations and adapt to the dynamic change in the environment with spiral maturity level identification.

Originality/value

A novel spiral maturity level identification is proposed with conceptual consistency for evolutionary progress to adapt to dynamic change. A measurement instrument that is incrementally structured with 234 statements and a measurement method that is based on the priority weights and leads to calculating the maturity index are designed to assess digital maturity, create an improvement roadmap to reach higher maturity levels and prioritize actions and investments without any external support and assistance.
Bibliometric mapping in the landscape of cybernetics: insights into global research networks
Authors: Nica Ionut
Published: February 2024

Purpose

This bibliometric mapping study aimed to provide comprehensive insights into the global research landscape of cybernetics. Utilizing the biblioshiny function in R Studio, we conducted an analysis spanning 1958 to 2023, sourcing data from Scopus. This research focuses on key terms such as cybernetics, cybernetics systems, complex adaptive systems, viable system models (VSM), agent-based modeling, feedback loops and complexity systems.

Design/methodology/approach

The analysis leveraged R Studio’s biblioshiny function to perform bibliometric mapping. Keyword searches were conducted within titles, abstracts and keywords, targeting terms central to cybernetics. The timespan, 1958–2023, provides a comprehensive overview of the evolution of cybernetics-related literature. The data were extracted from Scopus to ensure a robust and widely recognized source.

Findings

The results revealed a rich and interconnected global research network in cybernetics. The word cloud analysis highlights prominent terms such as “agent-based modeling,” “complex adaptive systems,” “feedback loop,” “viable system model” and “cybernetics.” Notably, the journal Kybernetes has emerged as a focal point, with significant citations, solidifying its position as a key source within the cybernetics research domain. The bibliometric map provides visual clarity regarding the relationships between various concepts and their evolution over time.

Originality/value

This study contributes original insights by employing advanced bibliometric techniques in R Studio to map the cybernetics research landscape. The comprehensive analysis sheds light on the evolution of key concepts and the global collaborative networks shaping cybernetics research. The identification of influential sources, such as Kybernetes, adds value to researchers seeking to navigate and contribute to the dynamic field of cybernetics. Furthermore, this study highlights that cybernetics not only provides a useful framework for understanding and managing major economic shocks but also offers perspectives for understanding phenomena in various fields such as economics, medicine, environmental sciences and climate change.
Efficacy and safety of epidural block with lidocaine for refractory severe plaque psoriasis: An open‐label pilot study in real world setting
Authors: Xu Xin , Yu Buwei , Lv Youwen , Cai Qing , Li Mengya , Li Guifeng , Li Qifang
Published: February 2024

Epidural block using lidocaine, a non‐selective blocker of voltage‐gated sodium channels (Nav), has demonstrated efficacy in the treatment of severe plaque psoriasis in a limited number of cases. This study aimed to evaluate the effectiveness and safety of epidural lidocaine block in adult patients with severe, treatment‐resistant plaque psoriasis. This was an open‐label pilot study. Patients with severe plaque‐type psoriasis unresponsive to at least one systemic treatment were enrolled for a 1‐week epidural lidocaine block and followed up for 48 weeks. Thirty‐six patients participated, with 32 completing the study. At the 12‐week mark, there was a remarkable 59% improvement in the mean Psoriasis Area Severity Index (PASI) score (P < 0.001). By week 48, 28 out of 32 patients (87%) achieved PASI 75, while 18 out of 32 (56%) reached PASI 90. Within 7 days, 20 out of 21 patients (95%) reported a reduction in itch, with a mean itch reduction of 82% at day 1 and 94% at day 7. Notably, no severe side effects were observed. Epidural lidocaine block proved to be an effective and safe long‐term treatment option for individuals with refractory severe plaque psoriasis.
Synergic actions of botulinum neurotoxin A and oxaliplatin on colorectal tumour cell death through the upregulation of TRPM2 channel‐mediated oxidative stress
Authors: Demir Sıdıka , Duman İpek , Nazıroğlu Mustafa
Published: February 2024

Botulinum neurotoxin A (BoNT) is being shown to have anticancer action as a potential adjuvant treatment. The transient receptor potential (TRP) melastatin 2 (TRPM2) stimulator action of BoNT was reported in glioblastoma cells, but not in colorectal cancer (HT29) cells. By activating TRPM2, we evaluated the impacts of BoNT and oxaliplatin (OXA) incubations on oxidant and apoptotic values within the HT29 cells. Control, BoNT (5 IU for 24 h), OXA (50 μM for 24 h) and their combinations were induced. We found that TRPM2 protein is upregulated and mediates enhanced BoNT and OXA‐induced Ca2+ entry in cells as compared to control cells. The increase of free reactive oxygen species (ROS), but the decrease of glutathione is the main ROS responsible for TRPM2 activation on H29 exposure to oxidative stress. BoNT and OXA‐mediated Ca2+ entry through TRPM2 stimulation in response to H2O2 results in mitochondrial Ca2+ overload, followed by mitochondrial membrane depolarization, apoptosis and caspase‐3/‐8/‐9, although they were diminished in the TRPM2 antagonist groups (N‐(p‐amylcinnamoyl)anthranilic acid and carvacrol). In conclusion, by increasing the susceptibility of HT29 tumour cells to oxidative stress and apoptosis, the combined administration of BoNT and OXA via the targeting of TRPM2 may offer a different approach to kill the tumour cells.
Physicochemical, structural, and emulsifying properties of stable blended whey and soy protein colloidal dispersion prepared by pH‐shifting and ultrasound
Authors: Liu Yaxuan , Gao Feng , Xia Boxue , Deng Jie , Liang Shuxia , Wang Cuina
Published: February 2024

This study investigated physiochemical, structural, and emulsifying properties of whey and soy protein blends (4%, w/v), which were combined at various proportions by pH‐shifting and ultrasound. The mixed dispersions exhibited small particle sizes (below 200 nm), with the smallest value observed at a sample with WPC to SPI ratio of 50:50. Reducing whey protein gave the blend lower surface hydrophobicity and higher α‐helix structure. More soy protein resulted in larger droplet size, lower surface charge, and greater flocculation of fabricated emulsions. Emulsions with soy protein lower than 50% were acceptable due to the nano‐scale size and small flocculation index.
Expression pattern analysis of transmembrane receptor TmToll‐8, −9, and −10 in the coleopteran insect Tenebrio molitor following systemic infection
Authors: Kojour MaryamAli Mohammadie , Jang Ho Am , Vasantha‐Srinivasan Prabhakaran , Lee Yong Seok , Jo Yong Hun , Han Yeon Soo
Published: February 2024

In insects, the production of antimicrobial peptides is considered to be the solo arm of the innate immune response. The Toll and immune deficiency pathways are two major signaling pathways that lead to the production of antimicrobial peptides as final effectors. The dynamic functions of Toll/Toll‐like receptors have been thoroughly reviewed in mammals and Drosophila. During the last decade, we have attempted to clarify the immunological roles of different Toll receptor variants and their ligands in Tenebrio molitor. Accordingly, we showed that TmToll‐8, −9, and −10 mRNA transcripts are induced following systemic injections of Gram‐negative, Gram‐positive, and fungal infections. Our data revealed harmonic expression patterns of TmToll‐8, −9, and −10 throughout the developmental stages of healthy individuals and in response to infections in the examined tissues (Malpighian tubules, gut, fat bodies, and hemolymph), illustrating similar evolutionary conversions of different Toll receptor variants in T. molitor. Taken together, our findings highlight the immunological actions of TmToll‐8, −9, and −10 in response to pathogenic insults in T. molitor.
Distribution of the N2‐fixing cyanobacterium Candidatus Atelocyanobacterium thalassa in the Mexican Pacific upwelling system under two contrasting El Niño Southern Oscillation conditions
Authors: Vieyra‐Mexicano Cinthya , Souza Valeria , Pajares Silvia
Published: February 2024

The unicellular cyanobacterium Candidatus Atelocyanobacterium thalassa (UCYN‐A) is a key diazotroph in the global ocean owing to its high N2 fixation rates and wide distribution in marine environments. Nevertheless, little is known about UCYN‐A in oxygen‐deficient zones (ODZs), which may be optimal environments for marine diazotrophy. Therefore, the distribution and diversity of UCYN‐A were studied in two consecutive years under contrasting phases (La Niña vs. El Niño) of El Niño Southern Oscillation (ENSO) along a transect in the ODZ of the Mexican Pacific upwelling system. Of the three UCYN‐A sublineages found, UCYN‐A1 and UCYN‐A3 were barely detected, whereas UCYN‐A2 was dominant in all the stations and showed a wide distribution in both ENSO phases. The presence of UCYN‐A was associated with well‐oxygenated waters, but it was also found for the first time under suboxic conditions (<20 μM) at the bottom of a shallow coastal station, within the oxygen‐poor and nutrient‐rich Subsurface Subtropical water mass. This study contributes to the understanding of UCYN‐A distribution under different oceanographic conditions associated with ENSO phases in upwelling systems, especially because of the current climate change and increasing deoxygenation in many areas of the world's oceans.
Simón Rodríguez and the sentimental roots of social republicanism
Authors: Castrillón Alejandro
Published: February 2024

In this article, I claim that Simón Rodríguez, a 19th‐century Venezuelan thinker, used and reconfigured Jean‐Jacques Rousseau's understanding of amour‐propre to construct a new political foundation for Latin America. He sought to channel it and other sentiments toward productive ends with a social education. In doing so, Rodríguez departs from Rousseau while still addressing the latter's political concerns regarding the benefits of egalitarian republicanism and the pitfalls of civilizational progress. Instead of accepting political models from antiquity, Rodríguez conceives of an egalitarian social republic uniting the rich and poor, White and people of color. While skeptical of European civilization built on commerce, he sees the possibility of a social civilization reconciling the interests of all in society. This comparative study of Rodríguez provides a necessary addition to the history of political philosophy while offering insights into a mode of thinking still informing contemporary politics in Latin America.
Hand eczema‐related presenteeism and sickness absence: A cross‐sectional population‐based study
Authors: Brands Marjolein J. , Loman Laura , Roelen Corné A. M. , Bültmann Ute , Schuttelaar Marie L. A.
Published: February 2024

Background

To date, hand eczema (HE)‐related presenteeism has never been assessed within the general population, and general population‐based studies on HE‐related sickness absence are limited.

Objectives

To assess the prevalence of HE‐related presenteeism and sickness absence, and factors associated with HE‐related presenteeism, within the Dutch general population.

Methods

Within the Lifelines Cohort Study, participants with HE in the last year (aged 18–65 in 2020), were identified by a questionnaire including questions regarding HE‐related presenteeism and sickness absence. Socio‐demographic factors were collected from 2006 to 2020.

Results

Out of the 3.703 included participants with HE, 2.7% (n = 100) reported HE‐related presenteeism, with 19.8% (n = 57) among those with severe‐to‐very‐severe HE. HE‐related sickness absence was reported by 0.5% (n = 20) and 5.9% (n = 17), respectively. Logistic regression analyses, adjusted for age and sex, showed negative associations between HE‐related presenteeism and higher educational attainment, higher income (>€2500) and higher occupational skill level, and positive associations for high‐risk occupations, chronic HE, moderate and severe‐to‐very‐severe HE (compared to almost clear), atopic dermatitis and occupational wet exposure.

Conclusions

A high prevalence of HE‐related presenteeism was found among participants with severe‐to‐very‐severe HE. Future studies should focus on longitudinal associations with the clinical course of HE, as HE‐related presenteeism might aggravate symptoms of HE.
Effect of comprehensive nursing care for the liver cancer patients undergoing interventional therapy in China: A systematic review and meta‐analysis
Authors: Zhang Shimei , Li Na , Mao Xuying , Yang Dongxia
Published: February 2024

Aims

This review aims to assess the effect of comprehensive nursing care on liver cancer patients undergoing interventional therapy in China.

Methods

In accordance with PRISMA guidelines, we reviewed randomized controlled trials and observational studies assessing the effect of comprehensive nursing care against standard care on liver cancer patients undergoing specific interventional therapies in China, including PubMed, Embase, CENTRAL and CINAHL till June 2023. Data synthesis was conducted using a random‐effects model and reported as pooled odds ratio (OR) or mean difference (MD) or standardized mean differences (SMD).

Results

Ten Chinese studies with 1682 participants were evaluated. Comprehensive nursing care significantly enhanced patient outcomes in liver cancer treatment. Quality of life improved markedly (OR: 0.16, 95% CI: 0.06–0.41). Notable reductions were observed in anxiety (MD: −8.96, 95% CI: −11.52 to −6.40) and depression (MD: −9.47, 95% CI: −11.79 to −7.14). Patients also experienced increased physical (SMD: 1.70, 95% CI: 1.15–2.25), social (SMD: 1.65, 95% CI: 1.14–2.16) and activity scores (SMD: 1.94, 95% CI: 1.49–2.39), alongside a decrease in post‐treatment complications (OR: 0.28, 95% CI: 0.21–0.37), demonstrating the multifaceted benefits of comprehensive care.

Conclusion

Comprehensive nursing care may improve patient outcomes in liver cancer treatment, offering potential benefits in reducing the side effects of interventional therapy.
Heart failure and the cost of dying: must the ferryman always be paid?
Authors: Sivanathan Vithoosharan , Smallwood Natasha , Ong Jeffrey , Wee Elin , Zentner Dominica
Published: February 2024

Background

Provision of palliative care in chronic heart failure (CHF) can support complex decision‐making, significantly improve quality of life and may lower healthcare costs.

Aims

To examine whether healthcare costs differed in terminal admissions according to the adoption of a palliative approach.

Design

Retrospective review of medical records and costing data for all admissions resulting in death from CHF (July 2011 to December 2019), analysed as two groups (2011–2016 and 2016–2019) because of background changes in costings.

Setting

Admissions with CHF resulting in death in an Australian tertiary referral centre.

Results

The cohort (n = 439) were elderly (median age 83.7 years, interquartile range (IQR) = 77.6–88.7 years) and mostly men (54.9%). Half (230, 52.4%) were referred to a specialist palliative care team, whereas over a third (172, 39.2%) received a palliative approach. Receiving a palliative approach was associated with a nonstatistically significant lower admission cost (AU$12 710 vs AU$15 978; P = 0.19) between 2011 and 2016 (n = 101, 38.8%) and a significantly lower cost (AU$11 319 vs AU$15 978; P < 0.01) between 2016 and 2019 (n = 71, 39.7%). Intensive care admission resulted in the single greatest additional cost at AU$14 624 (IQR = AU$4130–AU$44 197) (n = 48, 2011–2016). Median terminal admission cost was lower for patients with comfort goals of care (P < 0.01), without life‐sustaining interventions (P < 0.01) or who received a palliative approach (P < 0.01).

Referral to inpatient specialist palliative care or receiving a palliative approach resulted in comparable admission costings (AU$11 621 [IQR = AU$4705–AU$32 457] and AU$11 466 [IQR = AU$4973–AU$25 614]).

Conclusion

A palliative approach in terminal CHF admission may improve quality at the end of life and decrease costs associated with care.
Instructor's low guided gaze duration improves learning performance for students with low prior knowledge in video lectures
Authors: Shi Yawen , Chen Zengzhao , Wang Mengke , Chen Shaohui , Sun Jianwen
Published: February 2024

Background

Guided gaze is the instructor's gaze towards teaching materials to guide students' attention, and it plays a vital role in enhancing video‐based education. The duration of guided gaze, indicating how long instructors focus on teaching materials, varies based on the lecture design. Nevertheless, the impact of varying durations of guided gaze, especially concerning students' prior knowledge, remains inadequately understood.

Objectives

This study investigates the influence of the instructor's guided gaze duration and students' prior knowledge on learning performance and affective experiences in video lectures.

Methods

145 fifth‐grade students participated and were divided into high and low prior knowledge groups based on a pre‐test. Within each group, students were randomly assigned to view one of three video lectures with different guided gaze durations (high vs. medium vs. low). Learning performance and affective experiences (learning experience, satisfaction, and emotions) were measured as dependent variables.

Results and Conclusion

The results revealed that low guided gaze duration significantly improves learning performance for students with low prior knowledge. Conversely, high guided gaze duration negatively impacts learning experience, satisfaction, and positive emotions. Additionally, students with high prior knowledge reported higher learning experience and satisfaction. These findings highlight the interaction between guided gaze duration and prior knowledge in students' learning performance.

Implications

Our findings provide valuable implications for the design of guided gaze duration in video lectures based on students' prior knowledge. By adjusting guided gaze duration appropriately, instructors can optimise students' learning performance and affective experiences.
Morphochromatic spectrum through gonad development stages of the razor surgeonfish, Prionurus laticlavius (Valenciennes, 1846) (Actinopterygii: Acanthuriformes)
Authors: Aguilar‐Santana Fernando A. , Schmitter‐Soto Juan Jacobo , Lucano‐Ramírez Gabriela , Avila‐Poveda Omar Hernando , Arellano‐Martínez Marcial
Published: February 2024

Gonad development stages (GDS) are a critical tool that can be easily applied in fisheries to visually discriminate mature from immature organisms and assess their reproductive condition. This study proposes a morphochromatic scale to define gonad development stages for razor surgeonfish (Prionurus laticlavius) based on morphological and structural assessments of the gonad, histologically validated using multivariate dummy matrices modeled through multiple linear regression analyses. Gonads of 271 specimens were photographed prior to preservation to describe their shape, size, color, and turgor for morphochromatic analysis. Later, gonads were processed using standard histological methods. An oocyte growth scale was designed based on oocyte diameter and follicular wall thickness for each stage. In addition, five morphochromatic gonad development stages were histologically validated: immature, developing, spawning capable, regressing, and regenerating. Morphochromatic variations were observed in the last three stages in both sexes. Results show that gonad morphology and structure of P. laticlavius are similar to those of other acanthurids, albeit with some asymmetric and morphological differences, as well as gonad morphochromatic in both sexes. These findings confirm that maturation is species‐specific. Also, although not a critical character, gonad colouration was found to play a major role in distinguishing between gonad development stages along with shape, size, vascularity (females), and folds (males). Therefore, gonad colouration should not be entirely overlooked because doing so may lead to errors in determining sexual maturity stages.
Design and evaluation of pneumatic impact‐twisting combined walnut fixed posture shell‐breaking mechanism
Authors: Wang Yingbiao , Wang Zhoumei , Liu Mengdi , Wan Shuanglin , Zhang Chaoyu
Published: February 2024

The traditional walnut shelling methods, involving single‐stage or secondary processes, face challenges such as increased costs, uncertainties in shell positioning, and irregular crack expansion. To address these issues, this article introduces an innovative pneumatic impact‐twisting combined shelling method based on walnut fixed posture. The shelling mechanism design and orthogonal test were conducted, optimizing parameters like spring wire diameter (A), pressing head rotation angle (B), and cylinder locking air pressure (C) using evaluation criteria such as superior‐grade rate, intermediate‐grade rate, broken kernel rate, and shelling rate. Results indicate that the optimal shelling effect is achieved with a 3.5 mm steel spring wire diameter, a 100° downward pressing head rotation angle, and a 0.6 MPa cylinder locking air pressure on the pressure arm. The corresponding rates are as follows: superior‐grade rate 29.49%, intermediate‐grade rate 52.54%, broken kernel rate 10.14%, and shelling rate 91.04%. This study demonstrates that the pneumatic impact‐twisting combined walnut fixed posture shelling method improves post‐shelling quality, offering new design concepts for walnut shelling equipment.

Practical Applications

This introduces an innovative method that combines impact with twisting, and a pneumatic impact‐twisting combined walnut fixed posture shell‐breaking test device has been developed. Mechanical analysis was conducted for each stage of shell‐breaking. The research indicates that the pneumatic impact‐twisting combined method can enhance the production quality of walnut kernels after shell‐breaking. The test results indicate an improvement in the yield of 1/2 and 1/4 kernels compared to existing shell‐breaking methods. The inventive design of this shell‐breaking module contributes to the walnut kernel quality in the shell‐breaking production line, offering new methods and concepts for the design and advancement of walnut shell‐breaking devices.
A buried gneiss dome in the northern Gawler Craton: The record of early Mesoproterozoic (ca. 1600–1560 Ma) extension in southern Proterozoic Australia
Authors: Yu Jie , Hand Martin , Morrissey Laura J. , Payne Justin L.
Published: February 2024

Mabel Creek Ridge, in the northern Gawler Craton, is a granulite‐facies domain recording early Mesoproterozoic metamorphism, flanked by less metamorphosed rocks and dissected by crustal‐scale divergent structures. The nature of early Mesoproterozoic events is poorly understood due to the lack of basement outcrop. Calculated metamorphic phase diagrams and geochronology are used to decipher the tectonic regime of a potential gneiss dome. Pressure–temperature (P–T) modelling of metapelites from five drill holes across Mabel Creek Ridge suggests it has experienced conditions of ~6.4–7.4 kbar and 800–850°C and the growth of suprasolidus cordierite after garnet indicates subsequent decompression. In situ U–Pb monazite and Lu–Hf garnet geochronology constrains the granulite‐facies metamorphism of Mabel Creek Ridge to ca. 1600–1560 Ma. In contrast, drill hole GOMA DH4 located to the north of Mabel Creek Ridge records conditions of 2.2–5.4 kbar and 710–740°C at ca. 1520 Ma, with no evidence for 1600–1560 Ma metamorphism. Our new P–T pseudosection results and geochronology data from Mabel Creek Ridge and adjacent crust, coupled with the regional seismic and airborne magnetic data, reveal that Mabel Creek Ridge represents a record of early Mesoproterozoic extension in the Gawler Craton, during which thermally perturbed lower crustal rocks were exhumed within a gneiss dome. Early Mesoproterozoic extension took place within a complex geodynamic regime resulting from the interplay between final Nuna convergence along the margin of northeast Australia at ca. 1600 Ma and subduction to the southwest at ca. 1630–1610 Ma.
A method for crystallographic mapping of an alpha‐beta titanium alloy with nanometre resolution using scanning precession electron diffraction and open‐source software libraries
Authors: MacLaren Ian , Frutos‐Myro Enrique , Zeltmann Steven , Ophus Colin
Published: February 2024

An approach for the crystallographic mapping of two‐phase alloys on the nanoscale using a combination of scanned precession electron diffraction and open‐source python libraries is introduced in this paper. This method is demonstrated using the example of a two‐phase α/β titanium alloy. The data were recorded using a direct electron detector to collect the patterns, and recently developed algorithms to perform automated indexing and analyse the crystallography from the results. Very high‐quality mapping is achieved at a 3 nm step size. The results show the expected Burgers orientation relationships between the α laths and β matrix, as well as the expected misorientations between α laths. A minor issue was found that one area was affected by 180° ambiguities in indexing occur due to this area being aligned too close to a zone axis of the α with twofold projection symmetry (not present in 3D) in the zero‐order Laue Zone, and this should be avoided in data acquisition in the future. Nevertheless, this study demonstrates a good workflow for the analysis of nanocrystalline two‐ or multi‐phase materials, which will be of widespread use in analysing two‐phase titanium and other systems and how they evolve as a function of thermomechanical treatments.
Radiographically guided femoral neck osteosynthesis with cannulated compressive titanium screw and anti‐rotational component in a Brown Howler Monkey (Alouatta guariba clamitans)
Authors: Rovaris Inácio Bernhardt , Meyer Jacqueline , Rodrigues Paola Antunes , Surita Lívia Eichenberg , Picoli Roberta , Filho Fábio Trindade Dutra de Almeida , Monteiro Eduardo Raposo , Alievi Marcelo Meller
Published: February 2024

A Brown Howler Monkey presented with a femoral neck fracture was successfully treated with a cannulated compressive screw and an anti‐rotational component inserted with radiographically guided technique. Complete bone consolidation and functional recovery were observed 9 weeks after the surgery, and the monkey was released to his place of origin.