bluuebunny/crossref_metadata_2025 huggingface dataset:
Educación propia como rescate de la autonomía y la identidad cultural
Authors: Zuluaga Giraldo Jorge Iván , Largo Taborda Wilson Alejandro
Published: August 2021

Las comunidades indígenas en Colombia fundamentan su plan de vida desde los lineamientos establecidos por el Consejo Regional Indígena del Cauca (CRIC), que le da a cada pueblo potestad para adaptarlo según sus necesidades y expectativas. Dentro de su plan de vida, se encuentran elementos fundantes para el desarrollo de la comunidad como lo es su historia, la pervivencia de la cultura, su saber ancestral, la participación comunitaria, el territorio, la justicia, la salud, el ambiente y la educación propia como el conjunto de conocimientos del pueblo que se construye desde su avance y tradición que se transmite de generación en generación. En este sentido, se propone brindar una reflexión de la educación propia en el marco de la identidad, la autonomía y el desarrollo curricular, como una posibilidad para fortalecer el saber cultural desde la opción de vida de cada una de las comunidades indígenas. De esta manera, la educación propia se constituye en uno de los principales elementos de desarrollo, conocimiento, apropiación y avance de las prácticas culturales de cada uno de los territorios.
Emociones, inteligencias múltiples y rendimiento académico en universitarios
Authors: Rodríguez De Ávila Ubaldo Enrique , Paba Barbosa Carmelina , Paba Argote Zuany Luz , Obispo Salazar Kelly , Ceballos Ospina Guillermo Augusto , Cabas Manjarrés María Fernanda , Cervantes Perea Wendy , Vega Villa David Felipe , Munera Luque Kenia Melissa , Rodrigues De França Campos Fabiola , Chiombacamga Nafital Adriano
Published: August 2021

El rendimiento académico (RA), también conocido como desempeño académico, es una variable que interesa a estudiantes de todos los niveles, a profesores, padres de familia e investigadores. Es decir, todos aquellos que son afectados en cualquier medida y dimensión de actuación en el sistema educativo se interesan por esta variable, que siempre se ha tornado como desafiante para la formación de los jóvenes, especialmente los universitarios. Los autores discurren por los diferentes tópicos que sugiere el título de la obra, presentando, inicialmente, el carácter multimodal del RA; luego, se presentan las evidencias científicas acerca de las inteligencias múltiples con sus diferentes tipos y su implicación con el RA; después, el RA, en el cual se incluyen los estilos de aprendizaje, la autorregulación y la teoría de la emoción; posteriormente, continúa el capítulo que vincula aspectos biológicos tales como la preferencia circadiana o cronotipo, que incluye y explica el ciclo sueño-vigilia y el RA, así como la preferencia circadiana y el desempeño cognitivo, lo cual es un factor de estudio en los últimos años. Termina el libro con el capítulo dedicado a cómo los síntomas depresivos y la ideación suicida intervienen en el desempeño académico.
Cerebral Microbleeds and White Matter Hyperintensities are Associated with Cognitive Decline in an Asian Memory Clinic Study
Authors: Gyanwali Bibek , Lui Benedict , Tan Chuen S. , Chong Eddie J.Y. , Vrooman Henri , Chen Christopher , Hilal Saima
Published: August 2021

Background:

Cerebral Small Vessel Disease (SVD); lacunes, Cerebral Microbleeds (CMBs),
and White Matter Hyperintensities (WMH) have a vital role in cognitive impairment and dementia.
SVD in lobar location is related to cerebral amyloid angiopathy, whereas SVD in a deep location with
hypertensive arteriopathy. It remains unclear how different locations of SVD affect long-term cognitive
decline. The present study aimed to analyse the association between different locations and severity
of SVD with global and domain-specific cognitive decline over the follow-up interval of 3 years.

Methods:

We studied 428 participants who had performed MRI scans at baseline and at least 3 neuropsychological
assessments. Locations of lacunes and CMBs were categorized into strictly lobar,
strictly deep and mixed-location, WMH volume into anterior and posterior. The National Institute of
Neurological Disorders and Stroke-Canadian Stroke Network Harmonization Neuropsychological
Battery was used to assess cognitive function. To analyse the association between baseline location and
severity of SVD with cognitive decline, linear regression models with generalized estimated equations
were constructed to calculate the mean difference, 95% confidence interval and two-way interaction
factor between time and SVD.

Results:

Increased numbers of baseline CMBs were associated with a decline in global cognition as
well as a decline in executive function and memory domains. Location-specific analysis showed similar
results with strictly lobar CMBs. There was no association with strictly deep and mixed-location
CMBs with cognitive decline. Baseline WMH volume was associated with a decline in global cognition,
executive function and memory. Similar results were obtained with anterior and posterior WMH
volumes. Lacunes and their locations were not associated with cognitive decline.

Conclusion:

Strictly lobar CMBs, as well as WMH volume in anterior and posterior regions, were
associated with cognitive decline. Future research focuses are warranted to evaluate interventions that
may prevent cognitive decline related to SVD.
Cardiovascular Disease in Patients with Diabetes: A Comparison of Professional Society Guidelines
Authors: Sarkar Sudipa , Salazar Ilton M. Cubero , Tibuakuu Martin , Blumenthal Roger S.
Published: August 2021

In this review, we compare major points given in the 2021 American Diabetes Association
and the 2020 American Association of Clinical Endocrinologists/American College of Endocrinology
guidelines, in particular, the assessment and management of cardiovascular risk in patients
with diabetes with a focus on dyslipidemia, blood pressure, and pharmacotherapy in diabetes.
“Ferrites”: Synthesis, Structure, Properties and Applications
Authors: Mullick S.
Published: August 2021

Ferrites synthesis method and characterization techniques are attracting huge attentions of researchers because of their wide scope of uses in numerous areas. The ferrites include high resistivity, saturation magnetization, permeability, coercivity and low power losses. The above-mentioned useful ferrites characteristics make them appropriate for use in different applications. These ferrites are used in biomedical field for cancer cure and MRI. Electronic applications are transformers, transducers, and inductors which are also made using ferrites and also used in making magnetic fluids, sensors, and biosensors. Ferrite is a profoundly helpful material for many electrical and electronic applications. It has applications in pretty much every domestic device like LED bulb, mobile charger, TV, microwave, fridge, PC, printer, etc. This review mainly focus on the synthesis method, characterization techniques, and implementation of FNPs. This Chapter presents various methods used for ferrites preparation with distinctive examples, their advantages as well as limitations in detail. Ferrites properties like structural, optical, electrical and magnetic with their characterization techniques and various applications in the areas of biomedical, electronics, and environment are also discussed.
Multiferroicity in Aurivillius Based Bi4Ti3O12 Ceramics: An Overview, Future Prospective and Comparison with Ferrites
Authors: Bhardwaj S.
Published: August 2021

The growing modern society demands more new generation devices to fulfil their requirements. This has forced the scientific community to develop multifunctional smart devices. Aurivillius based Bi4Ti3O12 ceramics are one of the leading families of oxide materials, which attract immense attention due to their electrical, ferroelectric, optical, and dielectric properties. These materials have gained special attention due to their numerous device applications such as magnetic recording, sensors, read head technology, spintronic devices, switching devices, data storage devices and multiple state memory devices etc. Multiferroic are the materials in which two or more than two ferroic orders exist simultaneously. This chapter focuses on the possibility of existence of multiferroic behaviour in Aurivillius based compounds specially Bi4Ti3O12. Firstly, we have discussed the basics of multiferroics and their types and the magnetoelectric effect. The effect of different dopants in originating the multiferroism in Bi4Ti3O12 have been reviewed and discuss in detail. At the end comparison of multiferroic and ferrite materials and their future perspective have been discussed.
PRODUCTION, CONSUMPTION AND PRICE (IMPORTS, PRODUCERS AND CONSUMER) VOLATILITY OF SHALLOT IN PROBOLINGGO REGENCY
Authors: Sulistiowati Susanti Evie , Anindita Ratya , Asmara Rosihan
Published: August 2021

Changes in production, consumption, and import variables cause the price of shallots to fluctuate. A high and unpredictable price fluctuation increasing the volatility problem. This phenomenon gives results in risk, uncertainty and leading to a decline in the welfare of producers and consumers. Based on the description of the problems above, it is important to analyze price, production, import, and consumption volatility to determined the level of risk and uncertainty faced by producers and consumers. This study uses monthly secondary data (time series) on production, price, imports, and consumption of shallots in Probolinggo Regency, for seven years (2013-2019). The ARCH/GARCH method is used to analyze the volatility of prices, production and consumption. The results from the analysis are the production variable has a low level of volatility, the consumption and import prices have high-level volatility, producer price has low-level volatility, while consumer prices has-high level volatility. From the results means that the risks and uncertainties faced by producers in conducting shallot cultivation are low. While for the consumer means the risks and uncertainties in consuming shallots are high.
Retrospective Analysis of Autoimmune Diseases and Immunologic Characteristics of the Adult Primary Immune Deficiency Cohort: 17 Years Experience of the Tertiary Referral Immunology Center in Turkey
Authors: TUNAKAN DALGIÇ Ceyda , Zerrin Sin Aytül , Ardeniz Fatma Ömür
Published: August 2021

ABSTRACT Objective: Primary immunodeficiencies (PIDs) consist of genetically heterogeneous disorders. The spectrum can include infectious diseases, malignancy, allergy, and autoimmunity. We aimed to analyze the frequency and variety of autoimmune diseases (ADs) in PIDs and describe their clinical and laboratory features. Materials and Methods: Ninety-two patients with PID followed by Ege University Medical Faculty between 2000 and 2017 were enrolled in this retrospective, cross-sectional study. All patients’ medical records were reviewed using the demographic information, type of PIDs and ADs, ADs-related autoantibodies, and basic and immunologic laboratory findings. ADs were diagnosed using clinical and complementary paraclinical findings by an immunologist and/or a subspecialist related to the affected organ or system. Results: We evaluated 50 male and 42 female PID patients with a mean age of 40.92 (18-86). Twenty-nine (32 %) patients (15 females/14 males) with a mean age of 43.8 (19-78) had ADs. In our study group, the most commonly detected type of PID with AD is common variable immune deficiency (CVID) (n=17); followed by combined immune deficiency (CID) (n=3), CTLA4 deficiency (n=2), selective IgA deficiency (sIgAD) (n=2), specific IgG subgroup deficiency (n=1), autoimmune polyglandular syndrome (APS) with hypogammaglobulinemia (n=1), dyskeratosis congenita (DC) (n=1), Osler-Rendu-Weber (ORW) syndrome with CVID-like PID (n=1), and cartilage-hair hypoplasia (CHH) (n=1). According to systematic assessments, ADs resulted in endocrinologic 14%, dermatologic 10.8%, rheumatologic 9.7%, gastroenterological 9.7%, hematological 8.6%, and neurologic disorders 1%. The frequency of ADs was higher in CVID cases than other types of PIDs (p <0.05). Basic and immunologic laboratory findings of the PIDs with and without ADs were analyzed and compared; however, no statical significant difference was obtained between the groups. Conclusion: We have analyzed the frequency and variety of ADs in a adult PID cohort in Turkey. Patients presenting with multiple ADs should be screened for having an underlying PID. Keywords: Primary immune deficiency, autoimmunity, autoantibody, immunologic parameters, frequency
The Relationship Between Body-Mass Index, Central Obesity and Asthma in Children
Authors: Ay Arzu , Ucaryılmaz Hülya , Emsen Ayca , Artaç Hasibe
Published: August 2021

Objective: We hypothesized that, compared with body mass index (BMI) alone, central obesity would provide added information regarding types of asthma (allergic, nonallergic) and asthma severity. Materials and Methods: A total of 150 children aged between 7-17 years with 50 allergic asthma, 50 nonallergic asthma and 50 controls were included in the study. Height, weight, waist and hip circumferences of the groups were measured. Waist-to-hip ratio and BMI were calculated. Pulmonary function test results were recorded. The relation between anthropometric measurements, asthma, atopy, obesity and each other was analyzed. Results: Obesity according to BMI was higher in the group with allergic asthma than nonallergic asthma and the control group (p: 0.014). A positive correlation was found between asthma and BMI percentile, BMI z score and waist-to-hip ratio (p: 0.002; 0.003; 0.040, respectively). Children with obesity according to waist circumference were more frequent in the groups with allergic and nonallergic asthma compared to the control group (p: 0.048). There was a significant relationship between asthma severity and central obesity (p: 0.048). FEV1 / FVC and FEF25-75 were lower in the asthmatic groups compared to the control group (p: 0.028; 0.012, respectively). Conclusion: This study showed that central obesity was associated with asthma and asthma severity, but not with atopy. More investigation is needed to clarify how central obesity in children affects the control of asthma and the response to asthma medication. Keywords: Childhood asthma, central obesity, waist-to-hip ratio, body mass index
Prevalence of Allergic Diseases in Patients with Common Autoinflammatory Diseases
Authors: Erdoğan Tuba , yaşar Bilge Nazife Şule , Kaşifoğlu Timuçin
Published: August 2021

ABSTRACT Objective: Autoinflammatory diseases are driven by abnormal activation of the innate immune system. Although allergic diseases are known to be mediated by the T helper 2 response, new mechanisms are put forward about the activation of innate immunity during exposure to allergens in recent years. Familial Mediterranean fever (FMF) and Behçet’s disease (BD) are the commonly seen autoinflammatory diseases in Turkey. It was aimed to determine the prevalence of allergic diseases in BD and FMF and contribute to explaining the relationship between autoinflammation and allergic diseases in this survey. Materials and Methods: The study included 42 patients with BD, 40 with FMF, 20 with other rheumatic diseases, and 20 healthy controls who had volunteered for allergic evaluation. Patients were questioned about allergic diseases such as asthma, allergic rhinitis, atopic dermatitis, venom allergy, and food-drug allergy. The same prick test panel was used for all patients to investigate the presence of atopy. Results: Although the rate of allergic diseases and the blood eosinophil rate were significantly higher in patients with FMF and Behçet’s disease, which are commonly seen as autoinflammatory diseases, atopy rates were similar in all groups. The prevalence of allergic rhinitis and any allergic diseases was significantly higher in the FMF and BD groups (p: 0.03 and p: 0.02, respectively). In the multiple logistic regression model of the presence of any allergic disease, none of the factors was associated with allergic diseases. Conclusion: The prevalence of allergic diseases in patients with FMF and BD was found to be higher than in those with other rheumatic diseases and the control group but atopy rates were similar in all groups. The autoinflammatory diseases are not protective in terms of allergic sensitization and allergic rhinitis. This may be the result of recent advances in the innate immune sensing system. Keywords: Allergic diseases, autoinflammatory diseases, familial Mediterranean fever, Behçet’s disease, atopy
Oculocutaneous Albinism Type 7 with Recurrent Infections: A Case Report
Authors: Kılıç Mehmet , Özcan Mehmet Hazar , Taskın Erdal , Yıldırım Hakan , Şen Aşkın
Published: August 2021

ABSTRACT Oculocutaneous albinism (OCA) is a disorder of melanin biosynthesis characterized by hypopigmentation of the skin, hair, and retinal pigment epithelium. We present the clinical and laboratory features of two siblings, born to consanguineous Turkish parents, who were diagnosed with autosomal recessive OCA type 7. We detected a homozygous mutation in the C10ORF11 gene (p.A23Rfs * 39) in both patients. Interestingly, the medical history revealed that both patients had suffered from recurrent respiratory tract infections since birth. The patients were investigated for suspected immunodeficiency and the results of the immune screening assays were normal. We believe these patients are noteworthy to report since presentation with infections has not been described in the prior descriptions of OCA type 7. As of this current writing, infectious problems have stopped in one of our cases since the age of five and a half years. Keywords: Oculocutaneous albinism type 7, recurrent infection, immune system, genetic analysis, C10ORF11 gene
Pros and Cons of Nebulizer Treatment in Asthma Exacerbation During the COVID-19 Pandemic
Authors: ÖZTÜRK Ayşe Bilge , Baccıoğlu Ayşe , Uysal Soyer Özge , Civelek Ersoy , Şekerel Bülent Enis , Babek Sevim
Published: August 2021

ABSTRACT Nebulizers generate aerosols and may potentially transmit respiratory viral particles including SARS-CoV-2. There is a great concern about the use of a nebulizer in the treatment of asthma exacerbations in the hospital or home setting during the COVID-19 pandemic and its use is not recommended unless essential. However, aerosol therapy should not be avoided in obligatory indications. Therefore, indications of nebulizer use during the pandemic should be evaluated on an individual basis in case of a severe asthma attack, and infection control recommendations should be followed by clinicians while using nebulizers. In this article, we aimed to assess the safety in addition to the “pro” and “con” sides of nebulizer treatment in asthma exacerbation during the COVID-19 pandemic. Keywords: Asthma, coronavirus disease 2019, COVID-19, SARS-CoV-2, nebulizers
The General Features of Epic and Lyrical Poetry in the Kurdish- Gorany (Hawrami) Dialect
Authors: Mohammad Anwar Qader , Abdulrahman Lhon Qadr
Published: August 2021

The well- known Russian orientalist and Kurdolog, V.F. Minorsky was the first researcher who classified Gorany Poetry into three literary genres: Epic, Religion, and Lyrical poetries.
Our study is included within the frame of research of the literature of the Gorani (Hawrami) dialect. Therefore, we attempted to investigate this topic through the poetic methods of the two literary genres: Epic and Lyric to indicate their high level style and aesthetic values.
A Slantlet based Statistical Features Extraction for Classification of Normal, Arrhythmia, and Congestive Heart Failure in Electrocardiogram
Authors: Saeed Sawza Saadi , Yousif Raghad Zuhair
Published: August 2021

Intelligent and automated systems for diagnosing heart disease play a key role in treatment of heart disease and hence mitigating the possibility of heart disease, heart failure or sudden death. Thus, a Computer-Aided Design CAD system can provide a doctors with a clue about the category of patient heart disease, which might be Normal Sinus Rhythm, Abnormal Arrhythmia (ARR), and Congestive Heart Failure (CHF) electrocardiogram (ECG) signal. In this work a novel Slantlet transform (SLT) statistical features have been extracted and selected for 900 ECG segments taken from MIT-BIH ARR Database equally from three classes mentioned above for heart dieses classification through ECG signals. Based on the superiority of SLT in time localization as compared to the traditional wavelet transform, 12 out of 14 statistical features have been successfully passed the ANOVA test with P-value of 10−3. Then after, the relevant features are provided to three well-known classifiers (Support Vector Machine [SVM], K-nearest neighbor, and Naive Bayes). The performance tests show that Attaining 99.254% classification average AUC it can be achieved using SLT transform based features along with SVM classifier, which is a set of related supervised machine learning algorithm used for regression and classification with high generalization ability. It performs classification on two group problems. SVM classifier determines the best hyperplane which distinguishes between each positive and negative training sample.
The Luminosity Function of Galaxies in Some Nearby Clusters
Authors: Rasheed Mariwan Ahmed , Mohammad Khalid K.
Published: August 2021

In the present work, the galaxy luminosity function (LF) has been studied for a sample of seven clusters in the redshift range (0.0 ≲ z ≲ 0.1), within Abell radius (1.5 h−1 Mpc), in the five SDSS passbands ugriz. In each case, the absolute magnitude distribution is found and then fitted with a Schechter function. The fitting is done, using the χ2 – minimization method to find the best values of Schechter parameters Ф* (normalization constant), M* (characteristic absolute magnitude), and α (faint-end slope). No remarkable changes are found in the values of M* and α, for any cluster, in any passband. Furthermore, the LF does not seem to vary with such cluster parameters as richness, velocity dispersion, and Bautz–Morgan morphology. Finally, it is found that M* becomes brighter toward redder bands, whereas almost no variation is seen in the value of α with passband, being around (−1.00).
Comparison of Different Ensemble Methods in Credit Card Default Prediction
Authors: Faraj Azhi Abdalmohammed , Mahmud Didam Ahmed , Rashid Bilal Najmaddin
Published: August 2021

Credit card defaults pause a business-critical threat in banking systems thus prompt detection of defaulters is a crucial and challenging research problem. Machine learning algorithms must deal with a heavily skewed dataset since the ratio of defaulters to non-defaulters is very small. The purpose of this research is to apply different ensemble methods and compare their performance in detecting the probability of defaults customer’s credit card default payments in Taiwan from the UCI Machine learning repository. This is done on both the original skewed dataset and then on balanced dataset several studies have showed the superiority of neural networks as compared to traditional machine learning algorithms, the results of our study show that ensemble methods consistently outperform Neural Networks and other machine learning algorithms in terms of F1 score and area under receiver operating characteristic curve regardless of balancing the dataset or ignoring the imbalance
Assessing the Real-time Influence of Racism-Related Stress and Suicidality Among Black Men: Protocol for an Ecological Momentary Assessment Study
Authors: Adams Leslie , Igbinedion Godwin , DeVinney Aubrey , Azasu Enoch , Nestadt Paul , Thrul Johannes , Joe Sean
Published: August 2021

Background

Suicide is the third leading cause of death among Black adults aged 18-35 years. Although men represent a majority of suicide deaths among Black adults, less is known regarding the extent to which unique cultural stressors, such as racism-related stress (eg, racial discrimination), are salient in exacerbating suicide risk among Black men. Moreover, few studies examine the daily influence of racism-related stressors on suicide outcomes using real-time smartphone-based approaches. Smartphone-based mobile health approaches using ecological momentary assessments (EMA) provide an opportunity to assess and characterize racism-related stressors as a culturally sensitive suicide risk factor among Black young adult men.

Objective

The goal of this study is to describe a protocol development process that aims to capture real-time racism-related stressors and suicide outcomes using a smartphone-based EMA platform (MetricWire).

Methods

Guided by the Interpersonal Theory of Suicide (ITS), we developed a brief EMA protocol using a multiphased approach. First, we conducted a literature review to identify brief measures previously used in EMA studies, with special emphasis on studies including Black participants. The identified measures were then shortened to items with the highest construct validity (eg, factor loadings) and revised to reflect momentary or daily frequency. Feasibility and acceptability of the study protocol will be assessed using self-report survey and qualitative responses. To protect participants from harm, a three-tier safety protocol was developed to identify participants with moderate, elevated, and acute risk based on EMA survey response to trigger outreach by the study coordinator.

Results

The final EMA protocol, which will be completed over a 7-day period, is comprised of 15 questions administered 4 times per day and a daily questionnaire of 22 items related to sleep-related impairment and disruption, as well as racism-related stress. Study recruitment is currently underway. We anticipate the study will be completed in February 2023. Dissemination will be conducted through peer-reviewed publications and conference presentations.

Conclusions

This protocol will address gaps in our understanding of Black men’s suicide outcomes in the social contexts that they regularly navigate and will clarify the temporal role of racism-related stressors that influence suicidal outcomes.

International Registered Report Identifier (IRRID)

PRR1-10.2196/31241
Understanding the #longCOVID and #longhaulers Conversation on Twitter: Multimethod Study (Preprint)
Authors: Santarossa Sara , Rapp Ashley , Sardinas Saily , Hussein Janine , Ramirez Alex , Cassidy-Bushrow Andrea E , Cheng Philip , Yu Eunice
Published: August 2021

BACKGROUND

The scientific community is just beginning to uncover the potential long-term effects of COVID-19, and one way to start gathering information is by examining the present discourse on the topic. The conversation about long COVID-19 on Twitter provides insight into related public perception and personal experiences.

OBJECTIVE

The aim of this study was to investigate the #longCOVID and #longhaulers conversations on Twitter by examining the combined effects of topic discussion and social network analysis for discovery on long COVID-19.

METHODS

A multipronged approach was used to analyze data (N=2500 records from Twitter) about long COVID-19 and from people experiencing long COVID-19. A text analysis was performed by both human coders and Netlytic, a cloud-based text and social networks analyzer. The social network analysis generated Name and Chain networks that showed connections and interactions between Twitter users.

RESULTS

Among the 2010 tweets about long COVID-19 and 490 tweets by COVID-19 long haulers, 30,923 and 7817 unique words were found, respectively. For both conversation types, “#longcovid” and “covid” were the most frequently mentioned words; however, through visually inspecting the data, words relevant to having long COVID-19 (ie, symptoms, fatigue, pain) were more prominent in tweets by COVID-19 long haulers. When discussing long COVID-19, the most prominent frames were “support” (1090/1931, 56.45%) and “research” (435/1931, 22.53%). In COVID-19 long haulers conversations, “symptoms” (297/483, 61.5%) and “building a community” (152/483, 31.5%) were the most prominent frames. The social network analysis revealed that for both tweets about long COVID-19 and tweets by COVID-19 long haulers, networks are highly decentralized, fragmented, and loosely connected.

CONCLUSIONS

This study provides a glimpse into the ways long COVID-19 is framed by social network users. Understanding these perspectives may help generate future patient-centered research questions.
Hearing Loss in Patients With Morquio Syndrome: Protocol for a Scoping Review (Preprint)
Authors: Diaz-Ordoñez Lorena , Candelo Estephania , Silva-Cuero Katherine , Saldarriaga Wilmar , Murgašová Lenka , Magner Martin , Pachajoa Harry
Published: August 2021

BACKGROUND

Mild to moderate hearing loss is common in patients with mucopolysaccharidosis (MPS) IVA. The hearing loss can be conductive, sensorineural, or mixed. However, in these patients, the mixed form is frequent, attributed to the combination of conductive and neurosensory elements, with slowly progressive evolution. Conductive hearing loss may be secondary to recurrent upper respiratory tract infections, serous otitis media, and deformities of the ear ossicles due to the accumulation of glycosaminoglycans (GAGs). Meanwhile, the sensorineural form is mainly attributed to the accumulation of GAGs in the auditory system.

OBJECTIVE

The aim of this scoping review is to understand the extent and type of evidence in relation to the physiopathology, classification, epidemiology, and clinical management of hearing loss and the effect of therapy for hearing loss in patients with MPS IVA.

METHODS

This scoping review includes participants across all genders and of no particular age group who are diagnosed with MPS IVA and develop hearing loss as a comorbidity. No exclusion criteria (country, language, or document type) will be applicable. The information sources will include experimental and quasi-experimental, analytical observational, observational, and qualitative studies. Unpublished literature will not be covered. Grey literature will be covered. A total of 2 independent reviewers will participate in the process of screening the literature, paper selection, and data extraction, and this process will be performed blindly. When all manuscripts have been selected, disagreements that arise between the 2 reviewers at each stage of the selection process will be resolved through discussion or with an additional reviewer. Results will be reported with descriptive statistics and information will be displayed in a diagrammatic or tabular manner, as explained in the JBI guidelines.

RESULTS

The literature search was performed in November 2021 in MEDLINE, LILACS (Literatura Latino-Americana e do Caribe em Ciências da Saúde), the Cochrane Library, ScienceDirect, Google Scholar, and OpenGrey; a total of 780 results were retrieved. Completion of the review is expected in mid-2022.

CONCLUSIONS

This scoping review will be the first to describe the extent of the information regarding the development of hearing loss in the MPS IVA population. The data gathered by this review may lead to an understanding of the grade of hearing loss in this population and allow for the assessment of possible interventions according to the disease pattern.

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/32986
Parental Influences on Children’s Oral Health Behaviors, Reading Behaviors, and Reading Attitudes Associated with the Sharing of a Digital Story from the eBook for Oral Health Literacy© Curriculum
Authors: Ubbes Valerie A. , Witter Abby
Published: August 2021

This study investigated the relationships between parents and their children on oral health behaviors, reading behaviors, reading attitudes, and liking perceptions of one chapter from an eBook curriculum intervention. A Qualtrics platform was used to survey 316 parent-child dyads across the United States before and after the shared reading of one chapter from the eBook for Oral Health Literacy© entitled “Setting Goals for Going to the Dentist”. Participants answered 75 questions about their teeth brushing and flossing behaviors, number of cavities, how often they visited libraries and bookstores, enjoyment of reading, and perceptions (liking) of the words and pictures of the chapter that they read and heard. Statistically significant relationships were found between parents and their children on oral health behaviors (?2 = 49.12, p < 0.001); reading behaviors (?2 = 10.4, p < 0.01), reading attitudes (?2 = 8.773, p < 0.01), and perception (liking) of the eBook chapter that they read and heard (?2 = 113.813, p < 0.01). Results from 301 parent-child dyads point to the importance of social modeling that parents play in the development of their children’s oral health behaviors, reading behaviors, and reading attitudes. Testing of additional chapters from the eBook intervention is warranted.
Comparison of Biogas Concentrations in Various Environmental Conditions and Determination of the Optimal Period of Its Production at Environment Temperature
Authors: Demollari Edmond , Jojic Etleva , Sallaku Enkeleda , Vorpsi Valdete , Dodona Erta , Mema Olsid
Published: August 2021

Albania, as a part of Western Balkan, has a variety of climate systems. This type of climate has a closed connection with waste treatment process. The biogas volume produced by the experimental environmental was 0.6 m3. The maximum methane concentration in biogas was reached at 55.8%/volume. The enclosed area (in oval circle) is another indicator of this system. This area extends over the period from 14.08.2018 until 26.08.2018 (12 days). The biomethane maximum biogas concentration reached 53.5 %/vol. up to 55.8% vol. The concentration drop was 4.2 %/vol. The main factor was the temperature. In the period of maximum durability the temperatures were minimum 30°C and maximum 42°C. Another contributing factor was the inoculum. Since inoculum was made from the treatment of four types of waste of different nature, then the concentration of microorganisms was higher. The purpose of the comparison between the two experiments is the sustainability of biogas production as well as the biomethane concentration biogas concentration on waste treatment. Environmental temperature was studied in three different regions of Albania: Shkodra, Tirana and Vlora. The observations showed that the region of Vlora has the longest period of average daily temperature (June 14th to October 1st).
Tourism and Urbanization, An Interconnected Evolution
Authors: Gohar Amir
Published: August 2021

While there is extensive literature on the evolution of tourism and the urbanization process, the interlinks between these two evolutions are not yet fully explored; maybe because they are separate disciplines, or taught independently of each other. This research navigates the spatial dimension of travel evolution alongside the attendant expansion of the urbanization process. It defines the nexus between tourism as a global demand and the physical infrastructure that accommodates such a force. The built environment, manifested in both its urban forms and its systems of mobility, is shaped by, and has been shaping, many factors including tourism. Using comparative narratives that describes tourist curiosity, the tourism routs and the tourism destinations across time, this work further explores the historical relationship between urbanization and tourism by emphasizing how the evolution of each has influenced the other. Itanalyzes different eras and identifies how the tourist, the travel mode and the destination have influenced each other through time. Considered one of the world's oldest tourist destinations, Egypt is used here to demonstrate the interlocking relationship of tourism and urbanization. The research concludes that appreciating these two phenomena in isolation proves challenging insofar as the evolution of tourism through time can not only be attributed to the tourism demand but also to the shape and form of the destination and the mobile systems available in each era and locale.
Afro-descendants and social stratification in Mexico. New evidence from the 2015 Intercensal Survey
Authors:   El Colegio de la Frontera Norte, Torre-Cantalapiedra Eduardo , Sánchez-Soto Gabriela ,   Universidad de Houston
Published: August 2021

The 2015 Intercensal Survey marks the first time African descent self-identification was included on a nationally representative survey in Mexico. Before that, there were no nation-wide official counts of the Afro-Mexican population. In this paper we use ordinal logistic regression models to examine the effect of being Afro-descendant on the educational and occupational status of Mexi-cans. Contrary to expectations, our results show that, at the national level, there is no evidence that the self-identified Afro-Mexican population has a lower socioeconomic status than other Mexicans. This contradictory result may be attributed to a higher likelihood of Afro-descendant self-identification among more educated people, and lower among the most disadvantaged, par-ticularly in areas where Afro-Mexicans are less represented.
La enseñanza, lo femenino y la vida. Reseña del libro: Foucault, M. (2020) La sexualidad. Seguido de El discurso de la sexualidad
Authors: Valle Vázquez Ana María
Published: August 2021

Hasta ahora tenemos cuatro libros de Foucault dedicados a la experiencia ética del sexo: en los griegos con la aphrodisia, en los cristianos con la carne y en los modernos con la sexualidad.Hoy en 2020 celebramos el tomo cero titulado La sexualidad. Seguido de El discurso de la sexualidad, que trata de dos cursos impartidos por Foucault, el primero en 1964 y el segundo en 1969. La pregunta nodal y que puede articular a ambos cursos es: ¿qué es la sexualidad en nuestra cultura?
Crack Detection by Ultrasonic System on Locomotive-Track
Authors: Mayekar Vijay
Published: August 2021

Abstract: It has been found that major cause of the Railways accidents is due to the derailment attributed to the cracks developed on the rails. Crack development and its prolongation happens due to regular movement of locomotives, absence of timely detection. The maintenance lapse poses serious questions on the security of Railways transport operation. Manual detection of cracks on locomotive-tracks by maintenance team is arduous task, time consuming, irregular due to environmental factors and tight scheduling of trains, which may lead to maintenance work errors. This project aims at addressing the issue of crack detection by ultrasonic crack detection system, which would work in real time, with the control action taken to avoid major accident. Ultrasonic crack detection system is mounted on the locomotive itself, include precision ultrasonic sensor, LCD display, GPS module and its power supply. System will detect crack, subsequently it will generate Visual warning-signal for the authorities and generate location coordinates of the Crack. This will help for authority to generate caution signal for locomotives running on the same track for slow movement and emergency maintenance action could be undertaken. Keywords: locomotive-track, crack, ultrasonic Sensor, GPS Module, Arduino microcontroller
The integration of the authority of judicial institutions in solving general election problems in Indonesia
Authors: Siboy Ahmad
Published: August 2021

The authority to adjudicate general election problems/ disputes scattered in various judicial institutions has made the resolution process drawn out and, complicated, creating overlapping powers and the potential for conflicting decisions between judicial institutions. This study examines how the judiciary's authority is regulated in adjudicating election problems, why it is necessary to integrate judicial authority, and how the concept of the judiciary's power is in judging all general election problems. This research aims to map the judiciary's power and find the judicial institution's design with an authority to adjudicate all general election problems. This study used juridical-normative research with a statutory approach, conceptual and case approaches. The results show that the authority to judge general election problems is given to the Constitutional Court, Supreme Court, State Administrative Court, and District Courts of Appeal. The large number of judicial institutions authorized to judge has been proven to be incompatible with general election administration and judicial power administration principles. The authority to adjudicate all election issues must be exercised in one judicial institution. The judiciary that can exercise this authority refers to the Constitutional Court, the Supreme Court, or the exercise can be performed by establishing a remarkable judicial institution.
Transgender viewed from the perspective of positive law, health, and cultures in Indonesia
Authors: Wiryani Fifik , Ummah Nurul , Najih Mokhammad , Nasser Muhammad , Yunus Nur Rohim
Published: August 2021

Transgender people are seen as an abnormal minority group that bends the accepted sexual orientation against the cultures in Indonesia. This trend is also believed to be more prone to diseases. From the perspective of ius constitutum, transgender people are under different protection as set forth in Article 1 paragraph (3) of Law Number 39 of 1999 and Article 28 J of the 1945 Indonesian Constitution. However, the human rights governed are restricted to moral and religious, security, and public order rights. In the view of the positive law, in terms of health, every individual has the right to decide how they should live their life, but health is generally linked to diseases. When it comes to this matter, it can also be deemed inappropriate or deviant. Transgender people may be deprived of society, and they may have narrower room for their day-to-day activities such as mingling in religious activities and society, and even going to the restroom). This sexual tendency could also cause a serious disease like HIV/AIDS and irritate others due to their existence around them. In a different view, transgender people are recognized by the State that attempts to save them from conflicting thoughts of their existence. To conclude, being transgender is an inner disease existing in an individual. Although it is seen as normal by transgender people, this reality is still seen as discomfort by others.
PRAYER AS A FORM OF MANIFESTATION OF A SPECIFIC SACRIFICE (ON THE EXAMPLE OF THE TEXTS OF THE OLD TESTAMENT PRAYERS-BLESSINGS)
Authors:   SVETLANA N. VOROBYEVA  Tver State Technical University, VOROBYEVA SVETLANA N.
Published: August 2021

The article studies a prayer as a special form of interpersonal religious communication, the distinctive feature of which is the involvement of representatives of different worlds in the communicative process: the sacred and the profane. The philological analysis focuses on the Old Testament prayers - the blessings of God addressed to the first people Adam and Eve, as well as to the Old Testament saints Noah, Abraham, Isaac and Jacob. The study shows that the texts belong to the genre of prayer, as we have the relevant structural-semantic and functional features that identify it as text in this genre (the presence of the addresser and the addressee, the communicative goal; particular situation of communication; mechanism of text formation, etc.). The prayer of blessing is a form of expression of the specific victim, an example of which is the perfect love of God that caused the creation of the Universe and return the feeling of a man. Analyzing the biblical material, the author of the article comes to the following conclusions: 1) the divine word, the blessing is a manifestation of perfect love, through which covered not only the process of creation, but the creation itself; 2) appellative text directs the addressee to commit post-communistic action, which is directly connected with the implementation of the divine will, a manifestation of humility - certificate of perfect love on the part of the person; 3) the instrument of text formation prayers-blessings mechanism is deployed variable repetition; 4) the Old Testament model of prayer becomes a model of the textual organization of spiritual communication between God and man, man and God...
Niosomes as Nano-carrier Based Targeted Drug Delivery System
Authors: Joy Chanchal , Nair Smitha K. , Krishna Kumar K , Dineshkumar B
Published: August 2021

Niosomes are considered as novel nano-carrier in the drug delivery systems. These are much more stable than other nano-carriers like liposomes and nanoparticles. It is an example for targeted and control release of medication. The drug is entrapped into lipid core so that it prevents the drug from leaching. Here the drug will be targeted only to the desired cell/tissue and not to the non-targeted cells. By giving this formulation we can thereby reduce the dose of the drug and toxicity. This review article mainly emphasizes on the potential applications of niosomes in targeted drug delivery system.

Keywords: niosomes, nanocarriers, targeted drug delivery.
Experimental Design: Approaches and Applications in Development of Pharmaceutical Drug Delivery System
Authors: Supare Vinanti , Wadher Kamlesh , Umekar Milind
Published: August 2021

Conventionally, all the delivery systems have been prepared by methodology of trial and error concept by manipulating one variable at a Time, but attainment of optimal formulation is not achievable. The systematic approach Design of Experiments (DoE) enables researchers to provide appropriate outline to develop a best optimized delivery system. Optimization techniques using DoE helps to provide effective and economical analytical tools to find the perfect solution for a particular problem. In screening designs, there is large number of screening factors in minimum number of experiments and beneficial to minimize the variables in a desired size therefore further experimentation may be performed easily by using these variables. Experimental designs and optimization techniques are the tools which are systematically used to categorize various types of problems that may influence development of pharmaceutical delivery system. Use of experimental design is the best approach to the screening and optimization of experimental factors. In the present review article we have focused on application of practically applicable experimental designs and optimization techniques for the development of quality and efficacious of pharmaceutical formulations such as, nanoparticles, Phytosomes, microspheres, liposomes, micells, films, nanostructured lipid carriers and tablets and which type of factors to be considered while optimization are also discussed.

Keywords: Experimental design, Optimization, Applications, Drug delivery, Phytosomes, Nano delivery System.