bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnóstico da relação de degradação de solo e planta em área de cultivo de Eucalyptus urophylla com a presença de térmitas e formigas
Authors: Fernandes Paulo Ricardo de Sena , Ferreira Cibelle Christine Brito , Damascena Jossimara Ferreira , Silva Fabiano Rocha da , Lima Ítalo Cordeiro Silva , Barbosa Rone da Silva , Santos Antonio Clementino dos
Published: May 2021

Térmitas e formigas são agentes bióticos com alto nível de diversificação, indicando degradação do solo e deficiência nutricional do mesmo. Com os danos causados por eles, no solo e em plantas de eucalipto, faz-se necessário o controle dessas pragas, de maneira que, para o sucesso da aplicação do manejo integrado de pragas, a avaliação populacional desses indivíduos é fundamental, sendo imprescindível saber como eles se distribuem no campo. Dessa forma, objetivou-se investigar a dinâmica de distribuição espacial de ninhos de formigas e termitas em uma área de floresta plantada de eucalipto, bem como estudar o impacto causado por essas pragas no solo e na planta. Na avaliação dos atributos no plantio de Eucalyptus urophylla foram cinco: (1) o número de árvores mortas, (2) número de formigueiro e (3) número de ninhos de térmitas, (4) área dos formigueiros e (5) área dos ninhos de térmitas. Para os atributos de área de ninhos de formiga e térmitas foi coletado de 3 a 5 amostras das áreas, em seguida realizou a média, a fim de corresponder a cada ponto georreferenciado. Houve uma distribuição irregular dos ninhos de formigas e de térmitas pela área de estudo, atenuando a invasão do capim, principalmente em locais com maior número de ninhos de formigas, recomendando a manutenção deste povoamento em função destes agentes bióticos na área.
Botânica no Ensino Superior: o que pensam os discentes do Amapá (Amazônia, Brasil)
Authors: Alves Robson Marinho , Dias Ana Cristina Andrade de Aguiar , Gil André dos Santos Bragança
Published: May 2021

O presente trabalho teve como objetivo descrever as dificuldades encontradas pelos discentes no processo ensino-aprendizagem, dos conteúdos de Botânica em cursos de licenciatura em Ciências Biológicas e Naturais ofertados por Instituições de Ensino Superior (IES) públicas do estado do Amapá. Os dados foram coletados a partir da utilização de questionários, contendo perguntas referentes as particularidades dos discentes e do curso, os obstáculos relacionados aos conteúdos e carga horária das disciplinas, a metodologia docente e o que pode ser melhorado no ensino de Botânica. As respostas destacam os empecilhos que limitam a aprendizagem dos discentes no que se referem às estratégias didáticas aplicadas pelos docentes no ensino das disciplinas, a exiguidade de aulas práticas, a escassez de material didático e de espaços específicos para as aulas e a carga horária insuficiente para estudar as disciplinas de Botânica. Os resultados apresentados neste estudo recomendam o aperfeiçoamento do ensino de Botânica nos cursos de licenciaturas analisados, principalmente no que tange as estratégias e procedimento metodológico docente ao ensinar as disciplinas de Botânica.
Avaliação da função sexual de mulheres jovens brasileiras durante a pandemia de SARS-CoV-2: Um estudo observacional
Authors: Brilhante Magdalena Muryelle Silva , Marinho Maria de Fátima Duarte , Magalhães Adriana Gomes , Correia Grasiéla Nascimento
Published: May 2021

Introdução:A pandemia de SARS-CoV-2 gerou um impacto na saúde sexual e reprodutiva principalmente por ser uma doença com alta transmissibilidade entre indivíduos que mantém contato próximo. Objetivo: Avaliar o impacto do isolamento social na função sexual, qualidade de vida, e autoimagem de mulheres nulíparas, antes e durante a pandemia de SARS-CoV-2. Métodos: Estudo analítico observacional longitudinal, com mulheres de 18 a 35 anos, nulíparas, com ensino médio completo, que não realizaram tratamento fisioterapêutico prévio. A coleta de dados contemplava dados antroposociodemográficos e os questionários Female Sexual Function Index (FSFI), Short Form Health Survey 36 (SF-36), e a Escala de Silhuetas de Stunkard, Sorensen e Schlusinger (avaliação da autoimagem), aplicados antes e durante o isolamento social. A análise estatística foi realizada no GraphPad Prisma 6.0, e foi utilizado o teste de Shapiro Wilk, para analisar a distribuição da amostra, que foi não paramétrica, em seguida aplicou-se o Teste de Wilcoxon e a Correlação de Spearman. O nível de significância adotado foi p≤0,05. Resultados: Foram avaliadas 37 voluntárias, as variáveis sociodemográficas e o índice de massa corporal não apresentaram diferença entre as avaliações, durante o isolamento social o número de mulheres sedentárias aumentou (p<0.0001), a função orgástica melhorou (p=0,0081), a dor piorou significativamente no SF-36 (<0.0001), e quanto melhor foi o Estado Geral de Saúde do SF36 melhor foi a função sexual [p=0,04; r=0,37], na correlação da atividade física, o tipo de isolamento social e o escore total obtido no questionário FSFI, não foi verificado correlações significativas. Conclusão: O isolamento social, favoreceu a melhora da função orgástica, a piora da dor no SF-36, e não interferiu na insatisfação da imagem corporal, que permaneceu semelhante.
Validação do constructo e reprodutibilidade intra-avaliador do teste de degrau de 6 minutos em crianças saudáveis de 7-11 anos
Authors: Siqueira Pedro Paulo Simões de , Teixeira Juliana Baptista , Chaves Sulyvan Ítalo Daher , Lima Anna Myrna Jaguaribe de
Published: May 2021

Objetivo: Validar o teste de degrau de seis minutos (TD6M) e avaliar sua reprodutibilidade para determinação da tolerância ao esforço em crianças saudáveis de 7-11 anos. Métodos: Foram incluídas na pesquisa 66 crianças saudáveis, com idade entre 7 e 11 anos completos. Os voluntários foram submetidos ao teste de caminhada de seis minutos (TC6M) e ao TD6M, em ordem aleatória e dias diferentes, com intervalo de no máximo sete dias. Resultados: Foi observada uma correlação positiva moderada entre a distância percorrida no TC6M e o número de subidas no TD6M (r=0,43; p<0,001). A reprodutibilidade das variáveis no TD6M foi considerada excelente em relação às variáveis desempenho (número de degraus) (r=0,92; IC=0,87 a 0,87; p<0,001), pressão arterial sistólica (PAS) imediatamente após (r=0,87; IC=0,79 a 0,92; p<0,001), PAS-1’recuperação (r=0,84; IC=0,74 a 0,90; p<0,001), frequência cardíaca (FC) máxima (r=0,90; IC=0,83 a 0,94; p<0,001), FC-imediatamente após (r=0,88; IC=0,81 a 0,93; p<0,001) e Fadiga de membros inferiores (MMII)-durante o teste (3o min) (0,86; IC=0,78 a 0,92; p<0,001). Apresentaram também uma reprodutibilidade muito boa a PAS-repouso (r=0,75; IC=0,59 a 0,84; p<0,001), PAS-5’recuperação (r=0,78; IC=0,56 a 0,83; p<0,001), PAD-repouso (r=0,74; IC=0,58 a 0,84; p<0,001), pressão arterial diastólica (PAD) imediatamente após (r=0,72; IC=0,55 a 0,83; p<0,001), PAD-1’recuperação (r=0,77; IC=0,63 a 0,86; p<0,001), PAD-5’recuperação (r=0,73; IC=0,56 a 0,83; p<0,001), FC-repouso (r=0,73; IC=0,60 a 0,86; p<0,001), Fadiga de MMII-imediatamente após (r=0,72; IC=0,54 a 0,83; p<0,001). Conclusão: O TD6M é seguro, válido e com boa reprodutibilidade intra-avaliador na avaliação da tolerância ao esforço em crianças saudáveis entre 7-11 anos.
Pulsed-wave Doppler Ultrasound in canine reproductive system – Part 2: use in the routine
Authors: Carvalho Camila Franco de , Magalhães Jéssica Ribeiro , Magalhães Andreia Moreira , Guimarães Kyrla Cartynalle das Dores Silva , Moraes Reiner Silveira de , Sousa Daniel Bartoli de , Amaral Andréia Vitor Couto do
Published: May 2021

Given the importance of the reproduction field combined with the use of the Pulsed-Wave (PW) ultrasound in the clinical routine, this study aims to review the application of this diagnostic method in the reproductive tract of females and males of the canine species. A narrative review was carried out by using scientific articles, monographs, dissertations and thesis published and available in online databases: Periodical Capes (Coordination for the Improvement of Higher Education Personnel), SciELO (Scientific Electronic Library Online) and Google Scholar, in addition to specific books on the topic. In female dogs, Doppler ultrasound can be used to evaluate hemodynamic conditions in the estrous cycle (e.g. estimating day of ovulation and fertility, diagnosing early pregnancy, abnormalities, and fetal stress, thus ensuring greater obstetric safety) and identification of diseases, thereby avoiding unnecessary surgical interventions. In male dogs, however, Doppler ultrasound is mainly used in vascular evaluations in order to identify hemodynamic changes due to occurrence of benign prostatic hyperplasia (BPH), most common disease of the prostate and in the assessment of testicular arteries to better understand spermatogenesis and diseases that affect the testicle. In this review, we demonstrate that the use of Doppler mode ultrasound, especially the PW, allows dynamic analysis in clinical examination and complements important information in the diagnosis and treatment of different reproductive disorders in dogs.
Boas práticas na assistência ao parto natural
Authors: Costa Roberto de Sousa , Ferreira Janaína Pereira , Viana Magda Rogéria Pereira
Published: May 2021

O desenvolvimento de boas práticas na assistência ao parto normal, implementadas nas rotinas dos centros obstétricos, é importante, considerando-se a humanização do binômio materno-fetal, que favorece uma experiência positiva, bem como, contribui para o processo de parturição de forma que a mãe se sinta acolhida e possa manter saúde física e emocional, garantindo um parto sem complicações e que lhe traga boas recordações desse momento. O objetivo desse trabalho foi avaliar quais os conhecimentos sobre as boas práticas adotadas por enfermeiros que atuam na assistência ao parto natural, conforme as publicações científicas. Utilizou-se a revisão integrativa, em que 11 artigos científicos disponibilizados na íntegra, nos últimos 5 anos, selecionados na Biblioteca Virtual de Saúde, compuseram a amostra analisada. Os resultados demonstraram que, em todas as publicações foram empregadas boas práticas assistenciais, principalmente as não farmacológicas, por enfermeiros, para alívio da dor, oportunizando um trabalho de parto fisiológico e humanizado. Conclui-se que as estratégias empregadas pelos enfermeiros contribuem para o resgate do parto natural, que apresenta inúmeras vantagens para o binômio mãe e filho.
Perfil epidemiológico dos casos notificados de intoxicação exógena no Estado do Piauí, Brasil
Authors: Silva-Sampaio João Paulo da , Costa Renan de Lima , Torres Kely Naiara dos Santos , Sousa Nataniel Vieira de , Chaves Tatiana Vieira Souza , Gomes Júnior Antônio Luiz
Published: May 2021

Este trabalho teve como objetivo descrever o perfil epidemiológico de intoxicações exógenas notificadas no estado do Piauí - Brasil entre os anos de 2013 a 2017. Foi desenvolvida uma pesquisa de caráter exploratória, epidemiológica e descritiva com abordagem transversal, quantitativo e retrospectivo, os dados foram retirados do Sistema Nacional de Agravos de Notificações (SINAN) do Sistema Único de Saúde (SUS), o perfil evidenciou o predomínio do sexo feminino, faixa etária entre 20-39 anos, ensino fundamental incompleto, o agente tóxico mais frequente foram os medicamentos, as circunstâncias foram as tentativas de suicídios e com evolução de cura sem sequela na maioria dos casos. Foram registrados um total de 6.113 casos de intoxicações entre os anos analisados. Conclui-se, com esse estudo, a importância das notificações como proposta de implementação de melhorias contínuas das notificações e do preenchimento das fichas no SINAN, pois nos permitirá a obtenção de dados confiáveis e consistentes.
Dados cientométricos no contexto “desenvolvimento sustentável no Brasil” nos últimos 10 anos
Authors: Sampaio Raimundo Samuel Leite , Lima Elvis Estilak , Bezerra Janete de Souza , Pereira Kyhara Soares , Santos Luciano Temoteo dos , Sobral Selton David Cavalcante , Silva Joyce dos Santos , Oliveira Maraiza Gregorio de , Oliveira Rodolfo Sérgio de , Pereira Ginna Gonçalves , Pereira Francisco Diego , Oliveira Maria Aurea Soares de , Oliveira Bruna Almeida de , Gonçalo Maria Aparecida Barbosa Ferreira , Costa Adrielle Rodrigues
Published: May 2021

A preocupação com o desenvolvimento sustentável representa a possibilidade de garantir mudanças sociopolíticas que não comprometam os sistemas ecológicos e sociais que sustentam a vida. Neste contexto, foi realizado um levantamento bibliográfico e cientométrico em termos de desenvolvimento sustentável, ferramentas importantes para estudar e mensurar o progresso da ciência em análises quantitativas e qualitativas. A produtividade foi averiguada por meio das avaliações bibliométrica, utilizando bancos de dados de acesso a documentos da ciência, “Elsevier Scopus” entre o período: de 2009 a 2019, envolvendo as palavras-chave “Desenvolvimento Sustentável no Brasil”. A análise estatística foi expressa pelo programa GraphPad Prism 6. Em análise aos dados publicados no banco de dados da “SCOPUS”, foi possível observar que o primeiro trabalho publicado com o conceito “desenvolvimento sustentável no Brasil” foi em 1982, e ao longo os anos foi aumentando cada vez mais os estudos referente a este tema, tendo hoje 3.520 trabalhos registrados nesta plataforma. O Brasil se destaca com o maior número de trabalhos nestes últimos 10 anos, totalizando em torno de 1976 trabalhos, onde o ranking é liderado pela “USP- Universidade de São Paulo” uma Universidade consideravelmente importante no país, com atualmente 324. Dados como estes são promissores para averiguar como está a produtividade num respectivo assunto pelo país.
Estilo de vida de universitários: Análise de estudantes em diferentes turnos
Authors: Santos Amanda Lopes dos , Prati Sérgio Roberto Adriano , Santos Aline de Souza
Published: May 2021

Analisar o estilo de vida de universitários de diferentes turnos. Foram investigados 400 estudantes de uma universidade de Paranavaí-PR, 287 de Administração e 113 de Pedagogia; todos responderam ao questionário Estilo de vida Fantástico (EVF), composto por 25 questões, subdividido em 9 dimensões: Família e amigos (F); Atividade física (AF); Nutrição (N); Tabaco e drogas (TD); Álcool (Al); Segurança, estresse e atividade sexual (S); Tipo de comportamento (TC); Introspecção (I) e Carreira (C). Cada resposta atribui um valor de 0 a 4 pontos, totalizando escore máximo de 100 (quanto mais alto, melhor o estilo de vida). Em média os estudantes de Administração obtiveram 65,0±10,4pts e estudantes de pedagogia 67,6±10,9pts. Na comparação entre estudantes de turnos diferentes observou-se que não houve diferença estatística (P>0,05) entre estudantes de pedagogia (Vespertino, n=56, EVF= 67,8±10,7pts e Noturno, n=57, EVF= 67,4±11,2pts), em contrapartida estudantes de administração apresentaram diferença (P=0,01), sendo que estudantes do turno matutino (68,1±9,3) apontaram melhor EVF em relação ao noturno (64,1±10,6pts). Por fim, foi identificado que 35% dos estudantes de Administração alcançaram o escore mínimo (70pontos) considerado mais saudável e de menor risco, sendo 28% do período matutino e 71% do noturno. Quanto aos estudantes de Pedagogia, 45% obtiveram EVF considerado adequado, sendo 43% do vespertino e 56% do noturno. O Estilo de vida dos universitários é predominantemente inadequado; estudantes do período noturno apresentam pior estilo de vida quando comparado com estudantes diurnos e isso é mais evidente em estudantes do sexo masculino.
Application of an active oxygen (blue®m) with free connective graft technique for root coverage – a case report
Authors: Stroparo Jeferson Luis de Oliveira , Weiss Suyany Gabriely , Storrer Carmen Lucia Mueller , Deliberador Tatiana Miranda
Published: May 2021

Gingival recession occurs due to the migration of the gingiva in the apical direction, leading to compromising local aesthetics and root hypersensitivity. Connective tissue graft is the gold standard treatment in these cases improving both functional and aesthetics aspects.The purpose of this case is to report root coverage using the free connective tissue graftingtechnique (CTG) associated with topical application of active oxygen oral gel and mouthwash (blue®m). A 27-year-old female sought care with the main complaint of root hypersensitivity and the presence of gingival recession in the anterior region of the mandible. Clinical examination revealed the presence of type 1 gingival recession in the left mandibular central incisor. The treatment of choice was a modified graft (free connective graft). The graft and recipient bed received applications of blue®m oral gel. The patient was instructed to use blue®m mouthwash and blue®m oral gel after the surgery for 10 days. At 60 days, the patient showed satisfactory healing in the area of the free CTG, with gain of keratinized tissue and partial covering of the gingival recession. Free CTG with the support of the gel and the mouthwash with active oxygen release makes the technique viable, preventing graft necrosis and achieving root coverage and keratinized tissue.
Técnica e saberes tradicionais na formação profissional do Tecnólogo em Construção Civil
Authors: Cecilio Luiz Eduardo Camargo dos Santos , Freire Emerson
Published: May 2021

Buscando entender melhor a relação histórica do ser humano com a técnica, e indo além da dicotomia que sugere o par teoria e prática no âmbito da educação, o presente artigo procura trazer, passando pelo pensamento do filósofo francês Gilbert Simondon e do educador Jarbas Novelino Barato, cada qual no seu devido contexto, reflexões sobre o processo de ensino e aprendizagem em cursos de educação profissional e tecnológica. Trata-se de uma pesquisa bibliográfica e documental que busca discutir a relevância e as contribuições dos saberes tradicionais na trajetória de construção do perfil de profissionais Tecnólogos em Construção Civil, por sua vez diretamente ligados a cultura e ao pensamento contemporâneo. O recorte dessa pesquisa está centrado no estudo de documentos relacionados aos cursos de Tecnologia da Construção Civil e na análise da formação desses profissionais. Para tanto, pretende-se conceituar os termos destacados e relacioná-los à aspectos concretos do tipo de curso em questão.
Gestão estratégica de materiais: Uma proposta através da Matriz de Kraljic e da teoria dos jogos
Authors: Lima Douglas Leonardo de , Santos Osmildo Sobral dos , Coutinho Aparecido dos Reis
Published: May 2021

Analisando o cenário de competitividade entre as empresas, o setor de compras tornou-se um setor estratégico, assim, é possível perceber a constate busca das organizações por modelos estratégicos que possibilitem um alinhamento com os resultados esperados pelas corporações. O presente artigo busca propor um método alternativo para gestão estratégica na aquisição de materiais e serviços, através do modelo de compras criado por Peter Kraljic, que analisou os materiais a partir dos impactos financeiros causados por eles e os risco de suprimentos que estes representam. Junto a isto é proposto a utilização da Teoria dos Jogos, como estratégia de jogo a ser jogado para cada grupo de material.  Para isto, o método de pesquisa utilizado foi o método hipotético-dedutivo, bem como a revisão da literatura, feita através da leitura de livros, revistas e periódicos que relatam e relacionam-se com o assunto. Ao final um dos resultados observados é uma matriz estratégica para aquisição de materiais, onde para cada grupo de materiais, após classificados quanto ao risco financeiro e risco de suprimento é proposto um tipo de jogo. Entretanto, observa-se que o campo de estudo é muito vasto e passível de novos estudos.
Changes in health status of North Korean children and emerging health challenges of North Korean refugee children
Authors: Choi Seong-Woo
Published: May 2021

The food shortage in North Korea is a serious situation that has spanned the mid-1990s to today. North Korean refugee children, even those born in North Korea, China, or South Korea, had poor nutritional status at birth; thus, their growth and nutritional status should be continuously monitored. This review focused on the health status of North Korean children and the nutritional status of North Korean refugee children upon settling in South Korea. Immediately after entering South Korea, North Korean refugee children were shorter and lighter than South Korean children and had a serious nutritional status. Over time, their nutrition status improved, but they remained shorter and lighter than South Korean children. A new obesity problem was also observed. Therefore, it is necessary to continuously monitor their growth and nutritional status.
Prevention of dentoalveolar anomalies at an early age. Preventive check-ups
Authors:   Children's Dental Clinic No. 22, Karelova A.V. , Timonenko O.S. ,   Children's Dental Clinic No. 22, Vasyayeva L.E. ,   Children's Dental Clinic No. 22, Rybak O.G. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai, Tarmayeva S.V. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai
Published: May 2021

The article is focused on organizational measures that ensure the prevention of dentoalveolar anomalies in the system of dispensary observation, which should be set up taking into account the age periods of the child's development.
Sosialisasi Pencegahan Stunting pada Anak Balita di Kelurahan Cawang Jakarta Timur
Authors: Damanik Sri Melfa , Sitorus Erita , Mertajaya I Made
Published: May 2021

Stunting merupakan salah satu kondisi gagal tumbuh pada anak dimana tinggi badan anak <-2SD menurut tabel Z-score WHO. Ada beberapa hal yang menjadi penyebab utama masalah stunting pada anak, salah satunya yaitu ketidakoptimalan praktik pemberian makan anak. Tujuan Pelaksanaan Pengabdian kepada Masyarakat (PKM) ini yaitu untuk meningkatkan pengetahuan dan ketrampilan ibu tentang pencegahan stunting melalui edukasi praktik pemberian makan yang tepat berdasarkan rekomendasi WHO. Sebanyak 40 ibu yang memiliki anak Balita ikut dalam kegiatan PKM. Metode pelaksanaan PKM yaitu sosialisasi yang dikombinasikan dengan survei secara kuantitatif tentang pelaksanaan praktek pemberian yang dilakukan oleh ibu berdasarkan indikator praktik pemberian makan menurut rekomendasi WHO. Hasil PKM menunjukkan terdapat perbedaan yang signifikan antara nilai pre dan posttest peserta setelah diberikan sosialisasi di Kelurahan Cawang, Jakarta timur (P<0,001) dan 90 % ibu  mengalami peningkatan pengetahuan. Pemahaman ibu yang memiliki anak Balita tentang pencegahan stunting melalui pemberian makanan yang tepat dapat menurunkan risiko masalah stunting di Indonesia.
Sosialisasi Tentang Perlindungan dan Pencegahan Kekerasan dalam Rangka Kampanye 16 Hari Anti Kekerasan Terhadap Perempuan dan Anak
Authors: Sormin Elferida , Pramudini Puri , Nadeak Bernadetha , Yesyca Mita , Lase Formas Juitan , Panggabean Mompang L. , Novitasari Indah , Jovani Audra
Published: May 2021

Kegiatan Pengabdian kepada Masyarakat (PkM) dalam rangka perayaan 16 Hari Kampanye Anti Kekerasan Terhadap perempuan dan Anak yang digagas oleh Pemerintah Daerah Khusus Ibukota Jakarta melalui Dinas Pemberdayaan, Perlindungan Anak dan Pengendalian Penduduk (DPPAPP) DKI Jakarta menggandeng sepuluh perguruan tinggi mitra kerjasama yang ada di DKI Jakarta yang salah satunya adalah Universitas Kristen Indonesia (UKI) dan juga lembaga-lembaga terkait baik negeri maupun swasta. Kegiatan PkM ini diselenggarakan dalam berbagai bentuk, yakni: sosialisasi secara virtual dengan topik-topik yang berbeda namun tetap dalam tema besar yaitu anti kekerasan terhadap perempuan dan anak; dan juga pembuatan video seruan untuk memberantas kekerasan terhadap perempuan dan anak oleh Rektor UKI. Dalam kegiatan PkM ini, Tim UKI memperoleh kesempatan untuk pelaksanaan sosialisasi secara daring untuk empat topik, yakni: 1) Pembelajaran Jarak Jauh (PJJ), enjoy aja; 2) Cerdas Bermedia Sosial;3) Stop Trafficking! Tugas Kita Bersama; 4) Pencegahan Kekerasan di Tempat Publik. Dalam pelaksanaan sosialisasi secara Daring, selain dengan DPPAPP, UKI juga bekerjasama dengan UHAMKA dan STIE IPWIJA. Pelaksanaan sosialisasi berjalan dengan sangat baik diikuti oleh peserta baik yang bergabung secara langsung melalui ruang zoom sekitar 500 orang, dan juga yang menyaksikan melalui youtube channel, Facebook dan Instagram DPPAPP. Kegiatan sosialisasi secara daring ini mendapat respon yang sangat positif dari warga masyarakat, terbukti dari antusiasnya para peserta dalam mengajukan pertanyaan terkait topik yang dibawaka, yang selajutnya ditanggapi dengan sangat detail oleh para narasumber. Rangkaian kegiatan Kampanye 16 Hari Anti Kekerasan Terhadap Perempuan dan Anak juga mendapatkan penghargaan dari lembaga MURI dengan kategori viewers terbanyak, hampir mencapai 1 juta viewers.
Sources of funding regional smart specialization in Ukraine
Authors:   SI “Institute of Regional Research named after M. I. Dolishniy of the NAS of Ukraine”, DUB Andrii
Published: May 2021

Increasing the competitiveness level of regions based on smart-specialization is one of the foundations of regional development policy in Ukraine until 2027. Ukrainian regions have identified areas of their smart-specialization and formed projects for their implementation to achieve this goal. However, the smart-specialization projects require considerable financial resources. Identify and assess the financial sources for smart-specialization projects in Ukrainian regions, describe the weaknesses of the financial support mechanism for regions’ smart-specialization and suggest possible ways to eliminate them is the goal of our research. We analyzed regional development strategies and medium-term action plans of strategies’ implementation for identifying smart-specialization projects and the expected sources and scope of their financing. Then, we evaluated the possibility of financing the smart-specialization of Ukrainian regions from the expense of state and regional budgets, international organizations and domestic enterprises. State budget funds are the main financial resource for the introduction of regions’ smart-specialization. On average, almost half of the total planned funding for the regions’ smart-specialization projects comes from the state budget. The own funds of enterprises, grant funds, resources of international financial organizations, etc. – cover the second planned half of the regions’ smart-specialization projects’ cost. Funds from regional budgets will provide only a small need for funds for regions’ smart-specialization projects implementation. However, we found the absence of a separate financial support mechanism specifically for regions’ smart-specialization projects at both the state and regional levels. Conclusion. In Ukraine, there are sources of funds to start financing smart-specialization of regions. The range of tools for financial support of smart-specialization projects is quite wide. Besides, we propose to allocate part of the funds within the state and regional programs exclusively to the implementation of regions’ smart-specialization projects. We recommend introducing the funding for relevant projects on a revolving basis alongside non-repayable financial instruments to support regions’ smart-specialization.
Evaluation Of Foveal Thickness And Macular Choroidal Thickness With Optical Coherence Tomography in Behçet's Disease
Authors: BOZALİ Erman , ERDOĞAN Haydar , DURSUN Ayhan , VURAL ÖZEÇ Ayşe , TOKER İlker , ARICI Mustafa
Published: May 2021

Objective: The aim of this study is to evaluate foveal thickness and macular choroidal thickness on patients who were diagnosed with Behcet’s Disease (BD).
Materials and Methods: A total of 60 patients were included in this prospective cross-sectional study. Patients were divided into two groups. Group 1 consisted of 30 patients who were diagnosed with BD and Group 2 consisted of 30 healthy controls. Detailed ophthalmological examination was performed on both groups and foveal thickness and macular choroidal thickness were measured with Spectral Domain Optical Coherence Tomography (SD-OCT). To measure the choroidal thickness enhanced depth imaging OCT (EDI-OCT) technique was used.
Results: Mean foveal thickness in patients with BD was 216.06 ± 53.14 μm and mean subfoveal choroidal thickness was 363.21 ± 85.22 μm. Mean foveal thickness and subfoveal choroidal thickness in healthy controls was 211.65 ± 16.60 μm and 352.83 ± 87.11 μm respectively. There was no statistical significance between patients with BD and control group regarding foveal and subfoveal choroidal thickness. However, anatomical deformation of Elipsoid Zone structure in OCT had the most effect on visual acuity (p=0,001).
Conclusion: This study shows that there was no statistically significant difference in terms of foveal thickness and macular choroidal thickness in patients with BD.
Excitation Conditions for Surface-Enhanced Hyper Raman Scattering With Biocompatible Gold Nanosubstrates
Authors: Dusa Arpad , Madzharova Fani , Kneipp Janina
Published: May 2021

Surface enhanced hyper Raman scattering (SEHRS) can provide many advantages to probing of biological samples due to unique surface sensitivity and vibrational information complementary to surface-enhanced Raman scattering (SERS). To explore the conditions for an optimum electromagnetic enhancement of SEHRS by dimers of biocompatible gold nanospheres and gold nanorods, finite-difference time-domain (FDTD) simulations were carried out for a broad range of excitation wavelengths from the visible through the short-wave infrared (SWIR). The results confirm an important contribution by the enhancement of the intensity of the laser field, due to the two-photon, non-linear excitation of the effect. For excitation laser wavelengths above 1,000 nm, the hyper Raman scattering (HRS) field determines the enhancement in SEHRS significantly, despite its linear contribution, due to resonances of the HRS light with plasmon modes of the gold nanodimers. The high robustness of the SEHRS enhancement across the SWIR wavelength range can compensate for variations in the optical properties of gold nanostructures in real biological environments.
Categoricity, Variation, and Gradience in Sambla Balafon Segmental Encoding
Authors: McPherson Laura
Published: May 2021

This paper analyzes the musical surrogate encoding of Seenku (Mande, Burkina Faso) syllable structure on the balafon, a resonator xylophone used by the Sambla ethnicity. The elements of syllable structure that are encoded include vowel length, sesquisyllabicity, diphthongs, and nasal codas. Certain elements, like vowel length and sesquisyllabicity, involve categorical encoding through conscious rules of surrogate speech, while others, like diphthongs and nasal codas, vary between being treated as simple or complex. Beyond these categorical encodings, subtler aspects of rhythmic structure find their way into the speech surrogate through durational differences; these include duration differences from phonemic distinctions like vowel length in addition to subphonemic differences due to phrasal position. I argue that these subconscious durational differences arise from a “phonetic filter”, which mediates between the musician’s inner voice and their non-verbal behavior. Specifically, syllables encoded on the balafon may be timed according to the perceptual center (p-center) of natural spoken rhythm, pointing to a degree of phonetic detail in a musician’s inner speech.
High-Resolution 3D Seismic Imaging of Fault Interaction and Deformation Offshore San Onofre, California
Authors: Holmes James J. , Driscoll Neal W. , Kent Graham M.
Published: May 2021

The Inner California Borderland (ICB) records a middle Oligocene transition from subduction to microplate capture along the southern California and Baja coast. The closest nearshore fault system, the Newport-Inglewood/Rose Canyon (NIRC) fault complex is a dextral strike-slip system that extends primarily offshore approximately 120 km from San Diego to Newport Beach, California. Holocene slip rates along the NIRC are 1.5–2.0 mm/year in the south and 0.5 mm/year along its northern extent based on trenching and well data. High-resolution 3D seismic surveys of the NIRC fault system offshore of San Onofre were acquired to define fault interaction across a prominent strike-slip step-over. The step-over deformation results in transpression that structurally controls the width of the continental shelf in this region. Shallow coring on the shelf yields a range of sedimentation rates from 0.27–0.28 mm/year. Additionally, a series of smaller anticlines and synclines record subtle changes in fault trends along with small step-overs and secondary splay faults. Finally, sedimentary units onlapping and dammed by the anticline, place constraints on the onset of deformation of this section of the NIRC fault system. Thickness estimates and radiocarbon dating yield ages of 560,000 to 575,000 years before present for the onset of deformation.
Forecast Quality of Physics-Based and Data-Driven PV Performance Models for a Small-Scale PV System
Authors: Stüber Moritz , Scherhag Felix , Deru Matthieu , Ndiaye Alassane , Sakha Muhammad Moiz , Brandherm Boris , Baus Jörg , Frey Georg
Published: May 2021

In the context of smart grids, the need for forecasts of the power output of small-scale photovoltaic (PV) arrays increases as control processes such as the management of flexibilities in the distribution grid gain importance. However, there is often only very little knowledge about the PV systems installed: even fundamental system parameters such as panel orientation, the number of panels and their type, or time series data of past PV system performance are usually unknown to the grid operator. In the past, only forecasting models that attempted to account for cause-and-effect chains existed; nowadays, also data-driven methods that attempt to recognize patterns in past behavior are available. Choosing between physics-based or data-driven forecast methods requires knowledge about the typical forecast quality as well as the requirements that each approach entails. In this contribution, the achieved forecast quality for a typical scenario (day-ahead, based on numerical weather predictions [NWP]) is evaluated for one physics-based as well as five different data-driven forecast methods for a year at the same site in south-western Germany. Namely, feed-forward neural networks (FFNN), long short-term memory (LSTM) networks, random forest, bagging and boosting are investigated. Additionally, the forecast quality of the weather forecast is analyzed for key quantities. All evaluated PV forecast methods showed comparable performance; based on concise descriptions of the forecast approaches, advantages and disadvantages of each are discussed. The approaches are viable even though the forecasts regularly differ significantly from the observed behavior; the residual analysis performed offers a qualitative insight into the achievable forecast quality in a typical real-world scenario.
Quantifying Slopes as a Driver of Forest to Marsh Conversion Using Geospatial Techniques: Application to Chesapeake Bay Coastal-Plain, United States
Authors: Molino Grace D. , Defne Zafer , Aretxabaleta Alfredo L. , Ganju Neil K. , Carr Joel A.
Published: May 2021

Coastal salt marshes, which provide valuable ecosystem services such as flood mitigation and carbon sequestration, are threatened by rising sea level. In response, these ecosystems migrate landward, converting available upland into salt marsh. In the coastal-plain surrounding Chesapeake Bay, United States, conversion of coastal forest to salt marsh is well-documented and may offset salt marsh loss due to sea level rise, sediment deficits, and wave erosion. Land slope at the marsh-forest boundary is an important factor determining migration likelihood, however, the standard method of using field measurements to assess slope across the marsh-forest boundary is impractical on the scale of an estuary. Therefore, we developed a general slope quantification method that uses high resolution elevation data and a repurposed shoreline analysis tool to determine slope along the marsh-forest boundary for the entire Chesapeake Bay coastal-plain and find that less than 3% of transects have a slope value less than 1%; these low slope environments offer more favorable conditions for forest to marsh conversion. Then, we combine the bay-wide slope and elevation data with inundation modeling from Hurricane Isabel to determine likelihood of coastal forest conversion to salt marsh. This method can be applied to local and estuary-scale research to support management decisions regarding which upland forested areas are more critical to preserve as available space for marsh migration.
Mapping the Research Landscape on Poaching: A Decadal Systematic Review
Authors: Lavadinović Vukan M. , Islas Camila A. , Chatakonda Murali Krishna , Marković Nevena , Mbiba Monicah
Published: May 2021

Poaching is a widespread activity that affects wildlife management goals and undermines conservation efforts worldwide. Despite its complexity, poaching is still commonly addressed by researchers as a one-dimensional phenomenon. To deepen the scientific understanding of poaching, we conducted a systematic literature review in the Web of Science and Scopus databases for the last 10 years, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology. We found that most studies were carried out in Africa, although 43% of all articles on poaching were published by researchers from the United States and the United Kingdom. The most studied species are elephants (22%), rhinos (19%), wolves (9%), and bears (6%). Although this study identified a wide range of motives and drivers behind poaching activities, more than half of the analyzed articles do not attempt to provide a deeper understanding of this phenomenon. Its understanding of poaching usually does not go beyond the environmental impact of illegal hunting. Our study’s potential limitations may relate to the focus on exclusively English-language articles and, among them, only those discussing mammal, bird, and reptile species. Our findings indicate that global scientific knowledge on poaching in the last 10 years is biased. There is an imbalance between the developed countries that mostly produce knowledge on poaching (usually from Northern America and Europe) and the developing countries commonly an object of interest. This bias is potentially challenging, as the global scientific knowledge on poaching comes from limited experience based on charismatic species and selective case studies. To overcome this gap and develop a deeper understanding of poaching, the scientific community needs to overcome this bias and address illegal hunting wherever it affects the environment and undermines conservation efforts.
Whole-Exome Sequencing Reveals Rare Germline Mutations in Patients With Hemifacial Microsomia
Authors: Chen Xiaojun , Liu Fatao , Mar Aung Zin , Zhang Yan , Chai Gang
Published: May 2021

Hemifacial microsomia (HFM) is a rare congenital disease characterized by a spectrum of craniomaxillofacial malformations, including unilateral hypoplasia of the mandible and surrounding structures. Genetic predisposition for HFM is evident but the causative genes have not been fully understood. Thus, in the present study, we used whole-exome sequencing to screen 52 patients with HFM for rare germline mutations. We revealed 3,341 rare germline mutations in this patient cohort, including those in 13 genes previously shown to be associated with HFM. Among these HFM-related genes, NID2 was most frequently mutated (in 3/52 patients). PED4DIP, which has not been previously associated with HFM, exhibited rare variants most frequently (in 7/52 patients). Pathway enrichment analysis of genes that were mutated in >2 patients predicted the “laminin interactions” pathway to be most significantly disrupted, predominantly by mutations in ITGB4, NID2, or LAMA5. In summary, this study is the first to identify rare germline mutations in HFM. The likely disruptions in the signaling pathways due to the mutations reported here may be considered potential causes of HFM.
Cell Type-Specific Differentiation Between Indica and Japonica Rice Root Tip Responses to Different Environments Based on Single-Cell RNA Sequencing
Authors: Wang Zhe , Cheng Daofu , Fan Chengang , Zhang Cong , Zhang Chao , Liu Zhongmin
Published: May 2021

Background: As Oryza sativa ssp. indica and Oryza sativa ssp. japonica are the two major subspecies of Asian cultivated rice, the adaptative evolution of these varieties in divergent environments is an important topic in both theoretical and practical studies. However, the cell type-specific differentiation between indica and japonica rice varieties in response to divergent habitat environments, which facilitates an understanding of the genetic basis underlying differentiation and environmental adaptation between rice subspecies at the cellular level, is little known.

Methods: We analyzed a published single-cell RNA sequencing dataset to explore the differentially expressed genes between indica and japonica rice varieties in each cell type. To estimate the relationship between cell type-specific differentiation and environmental adaptation, we focused on genes in the WRKY, NAC, and BZIP transcription factor families, which are closely related to abiotic stress responses. In addition, we integrated five bulk RNA sequencing datasets obtained under conditions of abiotic stress, including cold, drought and salinity, in this study. Furthermore, we analyzed quiescent center cells in rice root tips based on orthologous markers in Arabidopsis.

Results: We found differentially expressed genes between indica and japonica rice varieties with cell type-specific patterns, which were enriched in the pathways related to root development and stress reposes. Some of these genes were members of the WRKY, NAC, and BZIP transcription factor families and were differentially expressed under cold, drought or salinity stress. In addition, LOC_Os01g16810, LOC_Os01g18670, LOC_Os04g52960, and LOC_Os08g09350 may be potential markers of quiescent center cells in rice root tips.

Conclusion: These results identified cell type-specific differentially expressed genes between indica-japonica rice varieties that were related to various environmental stresses and provided putative markers of quiescent center cells. This study provides new clues for understanding the development and physiology of plants during the process of adaptative divergence, in addition to identifying potential target genes for the improvement of stress tolerance in rice breeding applications.
Comparative Genomic Analysis of TCP Genes in Six Rosaceae Species and Expression Pattern Analysis in Pyrus bretschneideri
Authors: Zhao Yu , Su Xueqiang , Wang Xinya , Wang Mengna , Chi Xujing , Aamir Manzoor Muhammad , Li Guohui , Cai Yongping
Published: May 2021

TCP is a plant-specific transcription factor that plays an important role in flowering, leaf development and other physiological processes. In this study, we identified a total of 155 TCP genes: 34 in Pyrus bretschneideri, 19 in Fragaria vesca, 52 in Malus domestica, 19 in Prunus mume, 17 in Rubus occidentalis and 14 in Prunus avium. The evolutionary relationship of the TCP gene family was examined by constructing a phylogenetic tree, tracking gene duplication events, performing a sliding window analysis. The expression profile analysis and qRT-PCR results of different tissues showed that PbTCP10 were highly expressed in the flowers. These results indicated that PbTCP10 might participated in flowering induction in pear. Expression pattern analysis of different developmental stages showed that PbTCP14 and PbTCP15 were similar to the accumulation pattern of fruit lignin and the stone cell content. These two genes might participate in the thickening of the secondary wall during the formation of stone cells in pear. Subcellular localization showed that PbTCPs worked in the nucleus. This study explored the evolution of TCP genes in six Rosaceae species, and the expression pattern of TCP genes in different tissues of “Dangshan Su” pear. Candidate genes related to flower induction and stone cell formation were identified. In summary, our research provided an important theoretical basis for improving pear fruit quality and increasing fruit yield by molecular breeding.
The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges
Authors: Noviello Daniele , Mager Riccardo , Roda Giulia , Borroni Riccardo G. , Fiorino Gionata , Vetrano Stefania
Published: May 2021

Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract, characterized by a dysregulated innate and adaptive immune response to gut microbiota that contributes to the perpetuation of intestinal inflammatory processes. The Interleukin (IL) 23/IL17 axis has been reported to play a key role in UC pathogenesis promoting Th17 cells and cytokines-related immune response. Recently, the blockade of IL23/IL17 pathways has been raised enormous interest in the treatment o several chronic inflammatory disorders. In this review, we summarize the emerging results from clinical trials that evoked both promise and discouragement in IL23/IL17 axis in the treatment of UC. Targeting IL23 p40 through Ustekinumab results safe and effective to induce and maintain clinical remission, low inflammatory indexes, mucosal healing, and a better quality of life. Studies targeting IL23 p19 through Mirikizumab, Risankizumab, Brazikumab and Guselkumab are still ongoing. To date, no clinical studies targeting IL17 pathway are ongoing in UC. IL-17 targeting is thought to have a context-dependent biological effect, based on whether cytokine is selectively targeted or if its function is dampened by the upstream block of IL23.
Future Biomarkers for Infection and Inflammation in Febrile Children
Authors: Zandstra Judith , Jongerius Ilse , Kuijpers Taco W.
Published: May 2021

Febrile patients, suffering from an infection, inflammatory disease or autoimmunity may present with similar or overlapping clinical symptoms, which makes early diagnosis difficult. Therefore, biomarkers are needed to help physicians form a correct diagnosis and initiate the right treatment to improve patient outcomes following first presentation or admittance to hospital. Here, we review the landscape of novel biomarkers and approaches of biomarker discovery. We first discuss the use of current plasma parameters and whole blood biomarkers, including results obtained by RNA profiling and mass spectrometry, to discriminate between bacterial and viral infections. Next we expand upon the use of biomarkers to distinguish between infectious and non-infectious disease. Finally, we discuss the strengths as well as the potential pitfalls of current developments. We conclude that the use of combination tests, using either protein markers or transcriptomic analysis, have advanced considerably and should be further explored to improve current diagnostics regarding febrile infections and inflammation. If proven effective when combined, these biomarker signatures will greatly accelerate early and tailored treatment decisions.