bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Pengolahan Limbah Kotoran Sapi untuk Optimalisasi Pertanian Organik dan Kebersihan Lingkungan
Authors: Jauhani Muhammad Afiful , Fitriyah Arifatul , Wulandari Diny , Ramadhani Essa Hakim , Puspitasari Phinky , Salsabilla Shafira , Wari Aang Indras
Published: July 2024

Desa Klatakan, Kecamatan Kendit, Kabupaten Situbondo merupakan desa dengan mayoritas penduduknya beternak sapi. Fenomena pembuangan limbah kotoran sapi secara sembarangan masih banyak ditemukan padahal mengakibatkan dampak negatif bagi lingkungan, kesehatan, serta wisata di Desa Klatakan. Selain berternak masyarakat Desa Klatakan juga bertani. Saat ini terdapat beberapa permasalahan yang dihadapi oleh petani yaitu kelangkaan pupuk. Akibat dari langkanya pupuk menyebabkan harga pupuk semakin mahal, sehingga petani sangat sulit untuk memperoleh pupuk untuk kebutuhan bertani. Permasalahan tersebut dapat diatasi dengan diadakannya pelatihan pengolahan limbah kotoran sapi menggunakan metode fermentasi. Tujuan dari pengabdian masyarakat ini yaitu dapat mengurangi jumlah limbah kotoran sapi dengan kegiatan pelatihan tersebut, serta untuk meningkatkan kebersihan lingkungan dan mendukung pertanian organik di Desa Klatakan. Hasil dari kegiatan tersebut yaitu responden telah memahami bahaya membuang limbah kotoran sapi secara sembarangan, memahami pembuatan pupuk organik dari limbah kotoran sapi, serta para petani juga memahami bahaya pupuk kimia secara berkelanjutan dan manfaat penggunaan pupuk organik secara berkelanjutan.
Factores relacionados con la madurez y transformación digital en las Pymes manufactureras de Nuevo León
Authors: Puente Aguilar Elva Patricia , Lucas Marmol Antonio , Solís Peña Carolina
Published: July 2024

El objetivo de esta investigación es determinar los factores relacionados con la madurez digital de las Pymes manufactureras del estado de Nuevo León, a fin de contribuir en el conocimiento sobre su transformación digital. Mediante la revisión de literatura se definieron cinco variables independientes, capacidad de absorción del conocimiento, nivel de infraestructura tecnológica, cultura organizacional, capacidad de innovación y entorno de la empresa; como variable dependiente, se definió el grado de madurez digital. El diseño de la investigación fue cuantitativo, transversal, con alcance exploratorio y descriptivo correlacional. Se diseñó una encuesta para recopilación de datos que fue validada por un panel de expertos en el área. Para comprobar su fiabilidad, se realizó una prueba piloto y se midió el Alpha de Cronbach. Posteriormente se aplicó a empleados y directivos de 69 empresas Pymes manufactureras del estado. A partir de los datos se generó un modelo de regresión lineal múltiple en el software SPSS, el cual se sometió a diversas pruebas estadísticas para evaluar las variables y su significancia. El modelo resultó aprobado. Los resultados indicaron que tres de las variables, capacidad de absorción del conocimiento, nivel de infraestructura tecnológica y entorno de la empresa resultaron significativas con un p-value < 0.05. Adicionalmente se recomendaron análisis específicos para las dos variables que no fueron aceptadas. A partir del análisis estadístico se obtuvo una ecuación para medir el grado de madurez digital en Pymes manufactureras de Nuevo León que contribuye al avance en la transformación digital de las empresas manufactureras del estado.
PENGARUH BALLON BLOWING TERHADAP FATIQUE PASIEN DIABETES MELITUS TIPE 2 DI PUSKEMAS SIMPANG TIGA KOTA PEKANBARU
Authors: Azhar Bayu , Yani Fitri Hidayatul , Sriyanti Sriyanti , Zulirfan M
Published: July 2024

Diabetes mellitus is a non-communicable disease that causes the highest death in the world. The incidence of type 2 diabetes mellitus is quite high in the Simpang Tiga Health Center, Pekanbaru City. One of the complaints often experienced by people with diabetes mellitus is fatigue. Fatique in type 2 diabetes mellitus sufferers is influenced by physical and psychological factors, physical factors include complications, sleep quality, and pain while psychological factors are anxiety and depression. The purpose of this study was to determine the effect of balloon blowing on the fatigue of patients with type 2 diabetes mellitus. This research is quantitative in nature. This research was conducted at the Simpang Tiga Health Center in Pekanbaru City in May 2023 with 18 respondents. The research design used was a quasy experimental design, using the Fatique Serverity Scale questionnaire research instrument. The analysis used is the frequency distribution and the statistical test Paired-t test to see the effect on the variables. The results of the study concluded that there was a significant effect of balloon blowing on the fatigue of diabetes mellitus patients (p value 0.000 : a = 0.05). This researcher recommends to future researchers to conduct further research with a control group, and other interventions. So that the scope of discussion becomes wider.
Hubungan Tingkat Pengetahuan dengan Sikap Orang Tua Tentang Pemberian Pertolongan Pertama Cedera Pada Anak Berkbutuhan Khusus (ABK) Di SLB Denpasar
Authors: Dewi Gusti Agung Meidy , Wahyunadi Ni Made Dewi , Sriasih Ni Kadek
Published: July 2024

Latar Belakang : pengetahuan dengan sikap orang tua yang kurang baik dapat menyebabkan orang tua sering kali memilih tindakan yang tidak tepat ketika memberikan pertolongan pertama cedera pada anak, sehingga menimbulkan dampak kesehatan yang serius dan berunjung kematian pada anak, terlebih lagi pada anak berkebutuhan khusus (ABK) yang berisiko lebih tinggi mengalami cedera karena memiliki keterbatasan fisik, mental-inteklektual, sosial maupun emosional. Tujuan Penelitian: untuk mengetahui hubungan tingkat pengetahuan dengan sikap orang tua tentang pemberian pertolongan pertama cedera pada ABK di SLB N 1 Denpasar. Metedologi: desain yang digunakan pada penelitian ini adalah analitik korelasi dengan pendekatan cross sectional yang dilakukan pada bulan Maret – Mei 2023. Populasi dalam penelitian ini adalah orang tua yang memiliki anak berkebutuhan khusus yang bersekolah di SLB N 1 Denpasar. Menggunakan metode total sampling yaitu 231 responden. Instrumen yang digunakan berupa lembar kuesioner. Analisa data menggunakan uji spearmean rho. Hasil: mayoritas tingkat pengetahuan dan sikap orang tua tentang pemberian pertolongan pertama cedera pada ABK berkategori baik. Hasil uji statistik menggunakan spearmean rho didapatkan p <0,001 yang artinya ada hubungan tingkat pengetahuan dengan sikap orang tua tentang pemberian pertolongan pertama cedera pada ABK. Kekuatan kolerasi bernilai 0,476 dikatakan sedang serta arah kolerasi positif yang berarti semakin baik tingkat pengetahuan maka semakin baik pula sikap tentang pemberian pertolongan pertama cedera. Kesimpulan: mayoritas orang tua ABK memiliki pengetahuan dengan sikap yang baik sehingga perlu dipertahankan agar orang tua mampu menolong anak ketika mengalami cedera akibat kecelakaan rumah tangga atau kegawadaruratan lainnya.
SOME TRENDS IN DATA TRANSMISSION AND PROCESSING TECHNOLOGIES
Authors: Дудин Е.Б. , Сюнтюренко О.В.
Published: July 2024

Рассматриваются новые направления и значимые тенденции развития технологий передачи и обработки информации, такие как: пропускная способность каналов связи и скорость передачи данных; беспроводные сенсорные сети; программноконфигурируемые сети; высокопроизводительные вычисления, сетевые технологии управления; системы обработки и регистрации информации от различных средств обнаружения; системы питания летательных аппаратов энергией лазерного и СВЧ излучения; разработки антенн для базовых станций и подвижных систем связи. Показана взаимосвязь процессов развития информационных технологий с проблемами обеспечения информационной безопасности и задачами реиндустриализации российской экономики.

New directions and significant trends in the development of information transmission and processing technologies are being considered, such as: communication channel capacity and data transfer rate; wireless sensor networks; Software-configurable networks high-performance computing, network management technologies; systems for processing and recording information from various detection means; aircraft power supply systems with laser and microwave energy; designing antennas for base stations and mobile communication systems. It shows the relationship of information technology development processes with information security issues and the tasks of reindustrialization of the Russian economy.
INFORMATION TECHNOLOGY SUPPORT FOR TELECOMMUNICATION NETWORKS IN RUSSIA FOR THE INTEGRATION OF GLOBAL COMMUNICATION NETWORKS IN EURASIA
Authors: Сухоручкина И.Н. , Сухоручкина А.А.
Published: July 2024

Проанализированы сети связи международной экономической интеграции, зон свободной торговли, экономических, таможенных и валютных союзов, патентных и метрологических организаций в Евразии с участием России, законодательство госрегулирования сетей связи, проекты национальной программы «Цифровая экономика РФ», международные, европейские и российские стандарты кабельных систем связи. Классифицированы магистральные сети связи в России, наземные кабельные сети связи в Евразии через РФ - TEA NEXT, Европа - Россия - Азия ERA и DREAM, Европа - Россия - Япония ERJ, Европа - Россия - Монголия - Китай ERMC, Транзит - Монголия TMP, сеть Юго-Западной Азии SWAN, Супер Транзит Шелковый путь, TRANSKZ, подводные кабельные системы связи в Евразии с участием России - Межконтинентальный канал квантовой связи БРИКС, трансарктические кабельные линии связи Хельсинки - Токио и «Полярный экспресс» Мурманск - Владивосток, Россия - Япония RJCN, Хоккайдо - Сахалин HSCS, Италия - Турция - Украина - Россия ITUR, спутниковые системы связи России и с участием России - Globalstar, Inmarsat, Thuraya, Iridium, Intelsat, Eutelsat и Orbcomm. Проанализировано отражение НИОКР глобальных сетей связи в реферативных базах данных.

The communication networks for international economic integration, free trade zones, economic, customs and currency unions, patent and metrological organizations in Eurasia with the participation of Russia, the legislation for state regulation of communication networks, projects of the national program “Digital Economy of the Russian Federation”, international, European and Russian standards of cable systems have been analyzed. Backbone communication networks in Russia, terrestrial cable communication networks through Russia in Eurasia such as TEA NEXT, Europe-Russia-Asia ERA, Diverse Route for European and Asian Markets DREAM, Europe-Russia-Japan ERJ, Europe-Russia-Mongolia-China ERMC, Transit-Mongolia TMP, Southwest Asia Network SWAN, Super Transit Silk Road, TRANSKZ, submarine cable communication systems in Eurasia with the participation of Russia such as BRICS Intercontinental Quantum Communication Channel, Helsinki-Tokyo trans-Arctic telecom cable, Murmansk-Vladivostok “Polar Express”, Russia-Japan Cable Network RJCN, Hokkaido-Sakhalin Cable System HSCS, Italy-Turkey-Ukraine-Russia ITUR, satellite communication systems of Russia and with the participation of Russia such as Globalstar, Inmarsat, Thuraya, Iridium, Intelsat, Eutelsat and Orbcomm have been systematized. The global communication networks R&D reflection in abstract databases has been analyzed.
Development of Smart Solar Charge Controller on Wiznet W5500 IoT Platform
Authors: M.V.N. Srujan Manohar , O.A. Varun , P. Lavanya , Y. Sathwik , M. Madhu
Published: July 2024

The research represents a significant advance in solar energy technology, taking inspiration from nature's own efficiency mechanisms, particularly the heliotropic behavior of sunflowers. This research proposes the development and implementation of a solar energy system that dynamically adjusts the position of solar panels to track the movement of the sun throughout the day, maximizing energy capture and efficiency. The system uses a biomimetic approach, replicating the natural response of sunflowers to optimize exposure to sunlight. The main components of the system include LDR sensors for real-time sun position tracking, actuators for panel orientation adjustments, and a central control unit to manage system operations. This proposed study aims to address the limitations of traditional fixed solar panel systems, which are unable to adapt to changing sunlight angles throughout the day. The proposed system is also includes a MPPT based solar charge controller, with its response accessible through web servers and laptops/cell phones. The W5500 web server module integrated into the system serves as an IoT platform. Since web servers are platform-independent, they can be supported in cell phones/laptops allowing users to request relay evaluations and monitor solar charge controllers through the W5500 modules. The system can display battery charging status under various weather conditions and can be further enhanced to track other devices. The solar charge controller features multiple modules that enable IoT functionality, such as WIZNET (W5500), Arduino Nano (Atmega 328p), ESP32, solar panels, servo which are low cost and energy efficient.
RASTREAMENTO E PREVENÇÃO DO CÂNCER DE COLO DE ÚTERO
Authors: Dias Francisco Érbio , Nascimento Maria Eduarda Bezerra do , Sá Marcos Vinicios Alves de , Rosa Victor Hugo Júlio da , Balthar Mariana de Amorim , Oliveira Luanne Costa , Oliveira Bruna Stéfanny Mota de , Pessoa Beatriz Reis , Conceição Marcos Antonio da , Nunes Lohanna Gama , Juraci Sérgio Danillo Santana de Lima
Published: July 2024

Este artigo analisa as políticas e procedimentos para o câncer do colo do útero no Brasil, com foco na prevenção e rastreamento. Foi utilizada uma abordagem comparativa para identificar semelhanças e diferenças entre diretrizes e estratégias para a prevenção e rastreio do cancro da mama em todos os países. A pesquisa incluiu revisão da literatura, análise da literatura e de dados secundários e discussões com especialistas, tecnólogos e gerentes de projeto. Apesar das diferenças nas estratégias de rastreio do cancro, os outros países tem um programa bem estruturado com decisões e sistemas centrados a nível nacional para monitorizar o desempenho. O Brasil enfrenta problemas contínuos devido à falta de coordenação de medidas e falhas no setor feminino que alteraram os testes. As principais dificuldades na implementação de programas de rastreio do cancro da mama (incapacidade de rastrear populações em risco, falta de sistemas de controlo de qualidade, acompanhamento inadequado nas mulheres, os resultados são diferentes).
INFECÇÃO URINÁRIA NA PEDIATRIA: COMPREENDENDO SUAS REPERCUSSÕES: REVISÃO INTEGRATIVA
Authors: Silva Silvano Alves da , Miranda Arthur Pereira , Goes Maria Laura Vasconcelos Moreira Lopes de , Gusmão Herman Silva Brito Lima Buarque de , Ferraz Roger Kayan , Menezes Rafael da Silva Viana , Júnior Marcio Antonio Gomes Reis , Santos Bianca Meotti dos , Lemes Rodrigo Teixeira , Noronha João Pedro Homar de , Laurindo João Victor , Soares Gustavo Silveira , Santos Murilo Macêdo , Carvalho Renan Araujo de
Published: July 2024

Introdução: Infecção urinária na pediatria é uma condição clínica comum que afeta crianças e adolescentes, sendo uma das principais causas de consulta em serviços de emergência e ambulatórios pediátricos.
Metodologia: A fonte de busca incluiu bases de dados eletrônicas reconhecidas pela sua relevância e abrangência na área biomédica. As principais bases de dados selecionadas foram Google Acadêmico, Scielo e PUBMED. Estas fontes foram escolhidas devido à sua capacidade de fornecer acesso a uma vasta gama de estudos de alta qualidade, cobrindo diversas disciplinas e aspectos relacionados à temática proposta.
Resultados: Os métodos diagnósticos para infecção urinária na pediatria são essenciais para identificar com precisão a presença de infecção e para orientar o tratamento adequado. A coleta adequada de amostras de urina é crucial para evitar contaminações que possam comprometer os resultados dos exames.
Conclusão: Em resumo, as infecções urinárias na pediatria são uma condição comum, mas complexa, que requer uma abordagem abrangente para seu manejo. A compreensão das repercussões clínicas, emocionais e sociais dessas infecções é fundamental para o desenvolvimento de estratégias eficazes de diagnóstico, tratamento e prevenção.
Alterações Ecocardiográficas da Geometria e da Função Cardíaca em Pacientes com Lipodistrofia Familiar Parcial
Authors: Romano Minna Moreira Dias , Sapalo André Timóteo , Guidorizzi Natália Rossin , Moreira Henrique Turin , Inês Paula Ananda Chacon , Kalil Lucas Candelária , Foss Maria Cristina , Paula Francisco José Albuquerque de
Published: July 2024

Resumo Fundamento: A cardiomiopatia associada à lipodistrofia parcial (LP) ainda não foi bem descrita. Objetivo: Caracterizar a morfologia e a função cardíaca na LP. Métodos: Pacientes com LP e controles foram avaliados prospectivamente por ecocardiografia transtorácica e ecocardiografia por speckle-tracking (Strain Longitudinal Global, SLG). A relação entre as variáveis ecocardiográficas e o diagnóstico de LP foi testada com modelos de regressão, considerando o efeito da pressão arterial sistólica (PAS). Adotou-se um nível de significância de 5%. Resultados: Vinte e nove pacientes com LP foram comparados com 17 controles. Eles não se diferiram quanto à idade (p=0,94), sexo ou índice de massa corporal (p= 0,05). Os pacientes com LP apresentaram PAS estatisticamente mais alta (p=0,02) em comparação aos controles. Ainda, os pacientes com LP apresentaram maior dimensão do átrio (37,3 ± 4,4 vs. 32,1 ± 4,3 mm, p= 0,001) e maior volume atrial (30,2 ± 7,2 vs. 24,9 ± 9,0 mL/m2, p=0,02), massa do Ventrículo Esquerdo (VE) (79,3 ± 17,4 vs. 67,1 ± 19,4; p=0,02), e parâmetros sistólicos reduzidos do VE (E’ lateral, p= 0,001) (E’ septal, p= 0,001), (razão E/E’, p= 0,02). A fração de ejeção do VE (64,7 ± 4,6 vs. 62,2 ± 4,4 %, p = 0,08) e o SLG não foram estatisticamente diferentes entre os grupos (-17,1±2,7 vs-18.0 ± 2,0%, p= 0,25). Observou-se uma reação positiva do átrio esquerdo (β 5,6; p<0,001), espessura da parede posterior (β 1,3; p=0,011), E’ lateral (β -3,5; p=0,002) e E’ septal (β -3,2; p<0,001) com o diagnóstico de LP, mesmo após o ajuste para a PAS. Conclusão: Os pacientes com LP apresentam hipertrofia do VE, aumento do átrio esquerdo, e disfunção diastólica do VE apesar de fração de ejeção do VE e SLG preservados. Os parâmetros ecocardiográficos estão relacionados com o diagnóstico de LP, independentemente da PAS.
Echocardiographic Alterations of Cardiac Geometry and Function in Patients with Familial Partial Lipodystrophy
Authors: Romano Minna Moreira Dias , Sapalo André Timóteo , Guidorizzi Natália Rossin , Moreira Henrique Turin , Inês Paula Ananda Chacon , Kalil Lucas Candelária , Foss Maria Cristina , Paula Francisco José Albuquerque de
Published: July 2024

Abstract Background: Cardiomyopathy associated with partial lipodystrophy (PL) has not been well described yet. Objective: To characterize cardiac morphology and function in PL. Methods: Patients with familial PL and controls were prospectively assessed by transthoracic echocardiography and with speckle-tracking echocardiography (global longitudinal strain, GLS). The relationship between echocardiographic variables and PL diagnosis was tested with regression models, considering the effect of systolic blood pressure (SBP). Significance level of 5% was adopted. Results: Twenty-nine patients with PL were compared to 17 controls. They did not differ in age (p=0.94), gender or body mass index (p= 0.05). Patients with PL had statistically higher SBP (p=0.02) than controls. Also, PL patients had higher left atrial dimension (37.3 ± 4.4 vs. 32.1 ± 4.3 mm, p= 0.001) and left atrial (30.2 ± 7.2 vs. 24.9 ± 9.0 mL/m2,p=0.02), left ventricular (LV) mass (79.3 ± 17.4 vs. 67.1 ± 19.4, p=0.02), and reduced diastolic LV parameters (E’ lateral, p= 0.001) (E’ septal, p= 0.001), (E/E’ ratio, p= 0.02). LV ejection fraction (64.7 ± 4.6 vs. 62.2 ± 4.4 %, p= 0.08) and GLS were not statistically different between groups (-17.1 ± 2.7 vs. -18.0 ± 2.0 %, p= 0.25). There was a positive relationship of left atrium (β 5.6, p<0.001), posterior wall thickness, (β 1.3, p=0.011), E’ lateral (β -3.5, p=0.002) and E’ septal (β -3.2, p<0.001) with PL diagnosis, even after adjusted for SBP. Conclusion: LP patients have LV hypertrophy, left atrial enlargement, and LV diastolic dysfunction although preserved LVEF and GLS. Echocardiographic parameters are related to PL diagnosis independent of SBP.
Protective Effect of Long Noncoding RNA OXCT1-AS1 on Doxorubicin-Induced Apoptosis of Human Myocardial Cells by the Competitive Endogenous RNA Pattern
Authors: Chen Zhen , Liu Yijue , Ma Rui , Zhang Mengli , Wu Xian , Pen Huan , Gui Feng , Liu Yafeng , Xia Hao , Hu Niandan , Ai Bo , Xiong Jun , Xia Hongxia , Li Wenqiang , Ai Fen
Published: July 2024

Abstract Background: The anthracycline chemotherapeutic antibiotic doxorubicin (DOX) can induce cumulative cardiotoxicity and lead to cardiac dysfunction. Long non-coding RNAs (lncRNAs) can function as important regulators in DOX-induced myocardial injury. Objective: This study aims to investigate the functional role and molecular mechanism of lncRNA OXCT1 antisense RNA 1 (OXCT1-AS1) in DOX-induced myocardial cell injury in vitro. Methods: Human cardiomyocytes (AC16) were stimulated with DOX to induce a myocardial cell injury model. OXCT1-AS1, miR-874-3p, and BDH1 expression in AC16 cells were determined by RT-qPCR. AC16 cell viability was measured by XTT assay. Flow cytometry was employed to assess the apoptosis of AC16 cells. Western blotting was used to evaluate protein levels of apoptosis-related markers. Dual-luciferase reporter assay was conducted to verify the binding ability between miR-874-3p and OXCT1-AS1 and between miR-874-3p and BDH1. The value of p<0.05 indicated statistical significance. Results: OXCT1-AS1 expression was decreased in DOX-treated AC16 cells. Overexpression of OXCT1-AS1 reversed the reduction of cell viability and promotion of cell apoptosis caused by DOX. OXCT1-AS1 is competitively bound to miR-874-3p to upregulate BDH1. BDH1 overexpression restored AC16 cell viability and suppressed cell apoptosis under DOX stimulation. Knocking down BDH1 reversed OXCT1-AS1-mediated attenuation of AC16 cell apoptosis under DOX treatment. Conclusion: LncRNA OXCT1-AS1 protects human myocardial cells AC16 from DOX-induced apoptosis via the miR-874-3p/BDH1 axis.
Aproximações teóricas sobre a construção da identidade profissional docente na pós-graduação stricto sensu em turismo, hospitalidade e áreas afins no Brasil
Authors: Brito Adriana Santos , Netto Alexandre Panosso , Costa Perinotto André Riani
Published: July 2024

O artigo teve como objetivo compreender as atribuições teórico-reflexivas direcionadas aos cursos de pós-graduação stricto sensu em turismo, hospitalidade e áreas afins no Brasil, à luz da construção da identidade profissional docente. Ressalta-se nesta pesquisa que as atribuições teóricas e práticas ocorridas nas duas últimas décadas possibilitaram a criação da Associação Nacional de Pesquisa e Pós-Graduação em Turismo (ANPTUR), em 2002, organização que vem diversificando temáticas de ensino e pesquisa nessas áreas de estudos. A metodologia envolveu pesquisa de cunho qualitativa, descritiva-exploratória e bibliográfica. Após as análises propõe-se contribuições interdisciplinares que corroboram para novos olhares alinhados à construção da identidade docente (construção interdisciplinar). Nas considerações finais apresenta-se contribuições à luz do caminhar na docência e na pesquisa. Desta forma, propõe-se a realização de futuras investigações teóricas e/ou aplicadas para auxiliar em novas adequações direcionadas a melhorias relacionadas à formação de recursos humanos nesses cursos de pós-graduação stricto sensu em turismo, hospitalidade e áreas afins no país.
ABORDAGEM INTERDISCIPLINAR NO TRATAMENTO DO PACIENTE COM CÂNCER
Authors: Vitoria Oliveira Souza
Published: July 2024

A neoplasia maligna é uma condição crônica e progressiva que requer uma abordagem multidisciplinar para cuidados adequados. Este estudo tem como objetivo explorar, por meio de uma revisão de literatura, a dinâmica entre a equipe multiprofissional e o paciente oncológico, destacando a influência do relacionamento profissional-paciente no processo terapêutico. Utilizando uma abordagem de pesquisa bibliográfica, foram coletados dados da base de dados Scielo, utilizando os descritores Equipe de Assistência ao Paciente, Oncologia e Cuidados Paliativos. Este estudo reforça a importância do cuidado multidisciplinar para promover a integralidade da assistência à saúde do paciente oncológico, visando melhorar sua qualidade de vida. A revisão da literatura ressalta a necessidade de uma abordagem multiprofissional no cuidado oncológico, mas também identifica lacunas na implementação efetiva dessa abordagem na prática clínica. Portanto, é fundamental que o tema seja discutido e amplamente divulgado para incentivar a estruturação de equipes multiprofissionais na prestação de cuidados ao paciente com câncer.
REVISÃO INTEGRATIVA DA INTERAÇÃO FARMACOLÓGICA ENTRE O METRONIDAZOL E O ÁLCOOL: REAÇÃO DO TIPO DISSULFIRAM?
Authors: Ferreira Bernardo , Pereira Lívia , Dayrell Lorrany , Araújo Karina , Lemos Roberta , Alves Lucas
Published: July 2024

O alcoolismo é um problema de saúde relevante que atinge grande parte da população humana, cuja etiologia envolve múltiplos fatores, dentre eles cita-se os culturais e comportamentais. Nessa perspectiva, o álcool enquanto substância pode produzir dependência química e contribuir para o desenvolvimento de doenças crônicas, afetando a saúde e a qualidade de vida. O metronidazol é um antibiótico para infecções anaeróbias ou parasitárias, cujo efeitos colaterais indaga-se a intolerância ao álcool. Dessa forma, o objetivo do presente estudo foi descrever a interação do metronidazol com o álcool e elucidar a possível reação do tipo dissulfiram. A partir disso, foi realizada uma revisão integrativa na literatura, mediante seleção de artigos encontrados na base de dados da National Library of Medicine and National Institutes of Health (PubMed). De acordo com os resultados, a reação adversa do uso concomitante de metronidazol e álcool é inconclusiva, haja vista a limitação dos dados existentes, visto que há pontuações favoráveis ao aparecimento de sintomas negativos associados ao uso concomitante de metronidazol e álcool, mas também existem estudos que revelam à incerteza dessa relação. Portanto, se for o melhor tratamento proposto, não é recomendado o descarte do metronidazol para pacientes etilistas, mas não se pode subestimar a inexistência de qualquer interação entre o fármaco e o etanol.
CHARACTERIZATION OF CAPSULE MORPHOLOGIC PROPERTIES AND ALKALOID CONTENTS OF TURKISH POPPY GENOTYPES WITHIN ANKARA ENVIRONMENTAL CONDITIONS
Authors: Yanardag Y.K. , Day S , Bayraktar N
Published: July 2024

Poppy (Papaver somniferum) L. is cultivated commercially in several countries legally to produce alkaloids (i.e. morphine, codeine, thebaine, narcotine, papaverine and oripavine) for pharmaceutical industries. The demand for these alkaloids is increasing and Global climate change is influencing poppy cultivated areas. Türkiye is responsible for poppy cultivation, breeding new cultivars and adaptation trials. Therefore, the present investigation was undertaken during two years to examine the most cultivated 16 cultivars and 3 new lines for capsule morphology properties, their alkaloid values and capsule yield in Ankara conditions which is not in the poppy cultivation area in Türkiye. The experiment was arranged in the randomized complete block design with four replications. The plot size of 2.4 m² (2 m × 1.2 m) and 4 rows with spacing 30 cm between rows and 10 cm within plants were applied. The capsule parameters and alkaloid content were measured in 10 dry capsules after harvesting. To measure the content of alkaloids (%) the capsules were ground into powder and HPLC-MS/MS analysis after the solvent extraction of poppy straw on dry matter was conducted. Genotypes showed variation in stigmatic rays and the number of stigmatic rays was higher in the first year. The maximum stigmatic ray value was seen in cv. Ofis-95 with 13.27 in the first year. The maximum value for capsule length and diameter was obtained from cv. Ofis-NP (51.75 mm) and cv. Ofis-95 (45.00 mm) in the mean of two years. The maximum capsule yield was obtained from cv. Ofis-95 for both years and the values were 155.90 and 160.30 kg daˉ¹. The maximum morphine percentage was recorded in cv. Ofis-1 with 1.63 and 1.24% respectively. The percentage of noscapine, codeine, thebaine was noted as maximum values in Ofis-1 among genotypes. The results favoured the cultivation of these genotypes in Ankara which is not one of the poppy cultivation area and further agronomic studies should be undertaken to develop production technology of poppy in these environmental conditions.
Keywords: Papaver somniferum, cultivation, capsule yield, morphine, noscapine
EFFECT OF CRYO-STORAGE ON STORABILITY OF PAPAYA SEEDS
Authors: Kavitha S , Subhigha G , Manonmani S , Renugadevi J , Ambika S , Laksmi S , Thanga Hemavathy A , Thirusendura Selvi D , Vigneshweri R
Published: July 2024

A fruit crop of significant economic importance, papayas are often propagated from seeds. Based on their freezing injury even at low moisture content, papaya seeds are classified as "intermediate seeds"; and rapid loss of viability in storage is assumed to be the primary cause of poor germination; thus, the development of appropriate technology is necessary to prolong the storability of papaya seeds. One such effective technology for prolonged seed storability is cryo-storage. The purpose of the current study was to investigate how cryostorage affects papaya seed storability. For this investigation, TNAU Papaya variety CO 8 seeds were utilised. Five distinct treatments were applied to the seeds, which were then kept for approximately six months at liquid nitrogen's vapour phase (-140°C). The biochemical parameters such as protein content, free amino acid, total carbohydrates, free sugars, total lipids, and dehydrogenase activity were measured on a monthly basis along with seed germination and seedling vigour in the cryopreserved papaya seeds. Results indicated that papaya seeds that had been vitrified (seeds with a 10% moisture content that had been soaked in loading solution for 20 minutes, then immersed in Plant Vitrification Solution 2 (PVS2) for another 20 minutes, packed in cryovials and kept in cryo-storage at -140°C) compared to papaya seeds that were packed in cloth bags and stored in ambient conditions had higher seed germination, dry matter production and vigour index at six months after storage. In comparison to fresh seeds, the results also showed that, after six months of cryo-storage, biochemical proximate, protein content, total carbohydrate content, total lipid content, and dehydrogenase activity were maintained in the aforementioned treatment with minimum reduction, while electrical conductivity, free amino acid content, and free sugar content gradually increased with the storage period at minimum rate. In crux, vitrified papaya seeds packaged in cryovials and kept in cryo-storage at -140°C preserved their quality for six months, meeting Indian Minimum Seed Certification Standards. This could be useful for storing papaya seeds for longer periods of time.
Keywords: Papaya, vitrification, differential scanning calorimetry, liquid nitrogen, cryo-storage
ASSESSING THE ECONOMIC BENEFITS OF FOREST CARBON RESERVOIRS IN VIETNAM: IMPLICATIONS FOR FOREST CARBON TRADING MARKET DEVELOPMENT
Authors: Thanh D.T. , Ying Z , Huyen T.T. , Nguyen N.T.T.
Published: July 2024

The forest carbon sink is a cornerstone in Vietnam's strategy to combat climate change, aiming for carbon neutrality by 2050 as pledged during COP26. Assessing the economic benefits of Vietnam's current forest carbon sinks is crucial for initiating a domestic forest carbon trading market. Following protocols set by the Inter-Ministerial Committee on Climate Change in 2006, market valuation techniques to approximate the economic value of the forest carbon reservoir were employed. Results show Vietnam's forest ecosystems sequester about 1,401.52 million tons of carbon, equivalent to 5,143.60 million tons of CO2. The estimated economic value is approximately 25,717.95 million USD, with natural forests valued at about 87.44 million USD annually and planted forests at 63 million USD annually. These findings underscore Vietnam's capacity to establish and expand its forest carbon trading market. However, currently the establishment of Vietnam's forest carbon sink market is still in the preparatory phase and has not yet developed into an independent and complete trading system. Therefore, to optimize this potential, Vietnam needs to improve forest quality, promote sustainable forestry economics, and conduct scientific research to provide persuasive and reliable evidence, to support policies for the establishment and development of the forest carbon sink market.
Keywords: Biomass, economic value, forest carbon sink, market value method, stock volume, Viet Nam.
The Impact of Banking Penetration on Foreign Direct Investment in ASEAN: Comparative Analysis of Indonesia, Malaysia, and Thailand
Authors: Hidayat Ariodillah , Shodrokova Xenaneira
Published: July 2024

High banking penetration is considered an important indicator of the stability and maturity of a country's financial system, which can attract foreign direct investment (FDI). This phenomenon is becoming increasingly relevant in the ASEAN region, which continues to seek to increase its attractiveness for foreign investors amid global challenges. The study used secondary data from the International Monetary Fund covering the period from 2010 to 2021. The analysis was carried out using the regression of panel data of the Random Effect Model type. The results show that banking penetration has a significant positive impact on FDI in ASEAN. This confirms that foreign investors' confidence in the domestic financial system is very important. In Indonesia, strong banking penetration supports FDI growth despite regulatory and infrastructure challenges. In Malaysia, expanding access to digital financial services is important, while in Thailand, cooperation between the banking and telecommunications sectors is an example for other ASEAN countries. ASEAN countries need to focus on increasing banking penetration through policies that support digital financial services, improve corporate governance, and strengthen regional cooperation. The originality of this research lies in an in-depth comparative analysis of the impact of banking penetration in Indonesia, Malaysia, and Thailand, providing insights and policy strategies that can be adopted by other ASEAN countries to increase their FDI attractiveness.
Histological of the Epididymis after Lead (Plumbum) Exposure in Albino Mice Mus musculus
Authors: SARI DIAH KOMALA , WIDAYANTI GUSTI AYU , ARIFAH NUR
Published: July 2024

Lead or Plumbum (Pb) is a type of heavy metal-based chemicals that our body discontinue require for its proper functioning. When these chemicals enter the body in excessive amounts, they can harm the body's systems and increase the risk of cancer. Here we use albino mice Mus musculus. These small mammals often used in laboratorium research.This study to learn the effect of lead administration on the epididymal epithelium of albino Mus musculus mice. There are 18 mice divided into 3 treatment groups with 6 mice in each group (n=6). Every mouse in each group was given an intraperitoneal injection of Pb(NO³)² at a dose of 0 mgPb/kgBB, 5 mgPb/kgBBand 10 mgPb/kgBB. After 35 days, the treated mice were euthanized using the neck dislocation technique, and the epididymal epithelium was examined histologically. The findings of the study indicate that there was a reduction in the thickness of the epididymal epithelium, or thinning of the epididymal epithelium, in the group that received Pb when compared to the control group. The average tubule diameter in the control group was 7.125 mm, in 5 mbPb/kgBB it was 5.2083 mm, whereas in the 10 mgPb/kgBB treatment group, it was 4.3333 mm. This means that there was a significant difference in the thickness of the epididymal epithelium between the control group and the group given 5 mgPb/kgBB, 10 mgPb/kgBB. The results suggest that the administration of Pb is not safe for the epididymal epithelium at a dosage of  5mgPb/kgBB and 10 mgPb/kgBB
First records of Stigmatogobius yanamensis Visweswara Rao, 1971 (Perciformes: Gobiidae) in Indonesian waters
Authors: IQBAL MUHAMMAD , SETIAWAN ARUM , YUSTIAN INDRA
Published: July 2024

Stigmatogobius yanamensis is a small and cryptic goby, whose distribution remains poorly known. On 2 April 2016,  two specimens of S. yanamensis with a standard length of 20-21 mm were caught by hand net in the intertidal zone of estuarine mangroves, above a muddy substrate at the mouth of Sembilang River, South Sumatra Province, Indonesia. In addition, ten specimens were collected on 1-4 June 2023 in Sungsang (c. 40 km from Sembilang River) South Sumatra Province, Indonesia. This finding constitutes the first records of S. minima in Indonesian waters
Analisis Penggunaan Aplikasi E-Sumsel dalam Pembuatan Surat Tugas dan Taksasi SPPD Pada Badan Pengelola Keuangan dan Aset Daerah Provinsi Sumatera Selatan
Authors: Merti Paensi  , Mair Zaid Romegar , Indah Permatasari  , Muhammad Ikhwan Jambak
Published: July 2024

Surat Tugas merupakan surat dinas yang biasa digunakan untuk keperluan pekerjaan formal di lingkungan pegawai negeri sipil (ASN) untuk melakukan tugas kerja ke instansi atau kantor yang ada di tempat lain. Tujuannya yaitu untuk meneliti apa saja yang menjadi kepuasan dan ketidakpuasan pegawai sebagai pengguna aplikasi E-Sumsel dalam membuat surat tugas dan taksasi perjalanan dinas sehingga menjadi bahan evaluasi untuk meningkatkan kualitas dari aplikasi E-Sumsel pada pembuatan surat tugas dan taksasi perjalanan dinas. Sebelum adanya aplikasi E-Sumsel untuk memproses data perjalanan dinas, absensi, tunjangan penghasilan pegawai, gaji, pegawai ASN dan Non ASN masih menggunakan MS.Word dan MS.Excel sehingga sering terjadi Human Eror yang dimana data yang di peroleh tidak valid dan efisien. Dengan adanya aplikasi E-Sumsel yang digitalisasi maka informasi yang di peroleh lebih cepat, efisien dan efektif. Hasil dari Penelitian ini menggunkan Teknik pengumpulan data primer, yaitu data yang diperoleh dengan melakukan Penelitian secara langsung ke lokasi penelitian sesuai dengan masalah yang diteliti. Pengumpulan data ini dilakukan dengan cara Wawancara (Interview), Observasi, Kuesioner dan Dokumen.
Sistem Pengendalian Water Pump Untuk Mengatur Tinggi Level Air Dengan Fuzzy
Authors: Siregar Baginda , Muhammad Andre Apriansyah
Published: July 2024

Di beberapa wilayah Sumatera Selatan pada musim kemarau air bersih sulit ditemukan. Warga setempat mengandalkan sumber mata air dari perbukitan yang jauh dari pemukiman. Air bersih yang baik memiliki kriteria dan mutu, PDAM ialah perusahaan pengolah air yang tidak layak menjadi air bersih layak konsumsi.  PDAM memiliki plant Water Treatment sebagai tempat untuk mengelola air bersih. Salah satu prosedur pada plant ialah pengendalian level air secara konvensional. Masih ada tingkat error pada pengendalian level secara konvensional. Dibutuhkan kendali pada tingkat error agar pengendalian lebih efisien. Penerapan  logika fuzzy digunakan untuk memperkecil tingkat error. Logika fuzzy digunakan untuk kendali output nilai  PWM motor pada plant serta memiliki masukan pembacaan jarak dari sensor IR SHAR GP2Y0A21. Nilai PWM ditentukan dari aturan fuzzy berdasarkan nilai error dan beda error  yang dihasilkan dari pembacaan jarak oleh sensor. Nilai PWM yang dihasilkan berasal dari himpunan fuzzy.  Dari hasil yang dilakukan, pada saat level air 6 cm nilai error 14 serta nilai PWM yang dihasilkan sebesar 221 nilai PWM masuk pada himpunan cepat dan sangat cepat. Nilai PWM akan turun sampai nilai error 0 menghasilkan nilai PWM sebesar 190 yang masuk pada himpunan sedang. Penggunaan logika fuzzy pada plant bagian level  tepat dilakukan untuk  mengendalikan pompa sesuai pada tingkat error yang dihasilkan.
Analisis Sentimen Review Pengguna Viu Pada Play Store Dengan Algoritma Random Forest
Authors: Tangguh Prana Welas Sukma  , Pribadi Muhammad Rizky
Published: July 2024

Abstrak penelitian ini bertujuan untuk menganalisis sentimen review pengguna Viu di Google Play Store menggunakan algoritma Random Forest. Dengan lebih dari 100 juta unduhan dan 1 juta ulasan, aplikasi ini memberikan wawasan berharga mengenai persepsi pengguna terhadap layanan streaming video tersebut. Melalui analisis sentimen, penelitian ini mencoba memahami lebih dalam bagaimana respons pengguna terhadap Viu. Menggunakan teknik Synthetic Minority Oversampling Technique (SMOTE), penelitian ini mengatasi ketidakseimbangan kelas dalam dataset ulasan pengguna Viu. Hasil menunjukkan bahwa penerapan SMOTE meningkatkan stabilitas dan akurasi model, dengan peningkatan signifikan dalam akurasi, presisi, recall, dan F1-score. Dengan demikian, penelitian ini tidak hanya memberikan wawasan tentang sentimen pengguna terhadap Viu, tetapi juga mengevaluasi efektivitas teknik SMOTE dalam meningkatkan kinerja model analisis sentimen menggunakan algoritma Random Forest.
Kata kunci: Sentimen Analisis, Viu, Google Play Store, Random Forest, SMOTE.
Pengaruh Kualitas Produk, Kemasan dan Varian Produk terhadap Keputusan Pembelian Produk Mixue Ice Cream And Tea
Authors: Damayanti Alfina , Malau Riki Hanri
Published: July 2024

Keputusan pembelian adalah keputusan akhir dari konsumen untuk membeli atau tidaknya suatu produk dan jasa dengan banyak pertimbangan. Ketika melakukan keputusan pembelian, seringkali terdapat beberapa pilihan antara dua atau lebih alternatif. Tujuan penelitian ini adalah untuk mengetahui apakah ada pengaruh Kualitas Produk, Kemasan, dan Varian Produk terhadap Keputusan Pembelian produk Mixue Ice Cream and Tea (Studi Kasus pada Masyarakat Kota Pekanbaru). Dalam penelitian ini sampel berjumlah 100 orang responden dengan menggunakan teknik purposive sampling. Hasil uji data yang diperoleh, menunjukkan bahwa data valid dan reliabel. Selanjutnya pengujian dilakukan dengan regresi linier berganda, uji parsial (uji t), uji simultan (uji F), dan uji koefisien determinasi. Hasil dari penelitian ini menunjukkan bahwa terdapat pengaruh yang positif dan signifikan dari Kualitas Produk terhadap Keputusan Pembelian. Terdapat pengaruh yang positif dan signifikan dari Kemasan terhadap Keputusan Pembelian. Terdapat pengaruh yang positif dan signifikan dari Varian Produk terhadap Keputusan Pembelian. Kualitas Produk, Kemasan, dan Varian Produk secara simultan berpengaruh signifikan terhadap Keputusan Pembelian Produk Mixue Ice Cream and Tea. Besar pengaruh Kulitas Produk, Kemasan, dan Varian Produk terhadap Keputusan Pembelian Produk Mixue Ice Cream and Tea ditunjukkan dengan koefisien determinasi sebesar  0,583 (58,3%) dan sisanya 41,7% merupakan variabel lain yang tidak diteliti kedalam penelitian ini.
Exploring the Third Ventricular Floor Anatomy: Clinical Insights for Endoscopic Third Ventriculostomy
Authors: Martins Carolina , Tabarelli Luis Felipe Pohlmann , Campero Álvaro , Alencastro Luiz Felipe , Valença Marcelo Moraes , Wen Hung Tzu , Rhoton Jr. Albert
Published: July 2024

IntroductionSuccessful endoscopic third ventriculocisternostomy depends on understanding the third ventricle's floor and adjacent cisternal anatomical landmarks.ObjectiveTo explore the relationships among critical structures in this area to establish an anatomical classification for this region.MethodsSixty, silicone-injected, cadaveric heads were used. Measurements were taken at the level of third ventricular floor, cisterns, and tentorial edge, to classify the following: the size of the pre-mammillary area, suitable for third ventriculostomy; to determine whether the midbrain and optic chiasm are pre, normo or postfixed and to classify the size of the angle between the third nerves in the cistern.ResultsIn this study, pre-mammillary area sizes were classified as small (12.5%), medium (62.5%), and large (25%). Midbrain positioning was prefixed in 19%, midrange in 57.1%, and postfixed in 23.8% of cases. Chiasm positioning showed 20% prefixed, 65% normofixed, and 15% postfixed. A significant inverse relationship emerged between the midbrain-dorsum distance and the angle between the third nerves at the peduncle (p=0.001). As the dorsum-midbrain distance increased, so did the distance from the dorsum to the basilar artery, basilar artery to the midbrain, and the size of the pre-mammillary area (p<0.001). A wider tentorial edge also correlated with a greater distance between the third nerves (p<0.05).ConclusionThe midbrain's position significantly influences the safe space for third ventriculocisternostomy. A larger space is likely with a prefixed chiasm or postfixed midbrain. The midbrain position and tentorial notch width determine the lateral safety zone for a paramedian ventricular floor opening. Pre-operative assessment of these spatial relationships is useful.
PERAN TIKTOK DALAM MENINGKATKAN BRAND AWARENESS DI KALANGAN MILENIAL DAN GEN Z
Authors: Akbar Muhammad Fikri , Ati Henny Dewi Laras , Sukarson Ardian
Published: July 2024

Penelitian ini menginvestigasi peran TikTok dalam meningkatkan brand awareness di kalangan milenial dan Gen Z, fokus pada strategi pemasaran yang digunakan dan dampaknya terhadap persepsi dan ingatan konsumen. Metode campuran digunakan, menggabungkan survei kuantitatif dan analisis kualitatif. Hasilnya menunjukkan bahwa TikTok efektif dalam meningkatkan brand awareness melalui konten kreatif, tantangan hashtag, kolaborasi dengan influencer, dan iklan berbayar. Peningkatan keterlibatan pengguna, jumlah pengikut, viralitas konten, dan interaksi dengan konten merek menjadi indikator utama dampak TikTok terhadap brand awareness. Meskipun ada tantangan seperti kebutuhan akan kreativitas dan pemahaman terhadap algoritma, penelitian ini menyimpulkan bahwa TikTok adalah alat yang berharga dalam pemasaran digital, memungkinkan perusahaan untuk mencapai tujuan pemasaran mereka dan membangun brand awareness yang kuat di kalangan milenial dan Gen Z.
Impacts of Participation in Scientific Activities on Marine Tourists’ Engagement and Individual Learning Outcomes
Authors: Lucrezi Serena
Published: July 2024

Participation of marine tourists in scientific activities or Citizen Science can be considered a way to promote tourism that is educational, enriching, and valuable to the achievement of Sustainable Development Goals among other objectives set by the United Nations Ocean Decade. Whether
tourists’ experiences result in positive outcomes, however, requires continuous investigation. This study assessed the short-term impacts of marine tourists’ participation in scientific activities, with a focus on experiential and reflective engagement and individual learning outcomes,
and the potential influence of the former on the latter. A total of 111 tourists participated in a questionnaire survey following an experience of snorkeling/diving with a scientist to monitor the kelp forests of Cape Town during 2021‐2022. The results of the survey showed positive
impacts of the scientific experience on tourists. In particular, experiential and reflective engagement significantly positively influenced specific individual learning outcomes. These findings emphasize the importance of designing marine scientific tourism experiences that are engaging to
improve learning and result in positive behavioral intentions to partake in similar activities in future while supporting more sustainable forms of tourism.