bluuebunny/crossref_metadata_2025 huggingface dataset:
Chronic and Latent Viral Infections and Leukocyte Telomere Length across the Lifespan of Female and Male Individuals Living with or without HIV
Authors: Yang Nancy Yi , Hsieh Anthony Y. Y. , Chen Zhuo , Campbell Amber R. , Gadawska Izabella , Kakkar Fatima , Sauve Laura , Bitnun Ari , Brophy Jason , Murray Melanie C. M. , Pick Neora , Krajden Mel , Côté Hélène C. F. ,   CIHR Team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA)
Published: May 2024

Background: Chronic/latent viral infections may accelerate immunological aging, particularly among people living with HIV (PLWH). We characterized chronic/latent virus infections across their lifespan and investigated their associations with leukocyte telomere length (LTL). Methods: Participants enrolled in the CARMA cohort study were randomly selected to include n = 15 for each decade of age between 0 and >60 y, for each sex, and each HIV status. Cytomegalovirus (CMV), Epstein–Barr virus (EBV), human herpesvirus 8 (HHV-8), herpes simplex virus 1 (HSV-1), and HSV-2 infection were determined serologically; HIV, hepatitis C (HCV), and hepatitis B (HBV) were self-reported. LTLs were measured using monochrome multiplex qPCR. Associations between the number of viruses, LTL, and sociodemographic factors were assessed using ordinal logistic and linear regression modeling. Results: The study included 187 PLWH (105 female/82 male) and 190 HIV-negative participants (105 female/84 male), ranging in age from 0.7 to 76.1 years. Living with HIV, being older, and being female were associated with harbouring a greater number of chronic/latent non-HIV viruses. Having more infections was in turn bivariately associated with a shorter LTL. In multivariable analyses, older age, living with HIV, and the female sex remained independently associated with having more infections, while having 3–4 viruses (vs. 0–2) was associated with a shorter LTL. Conclusions: Our results suggest that persistent viral infections are more prevalent in PLWH and females, and that these may contribute to immunological aging. Whether this is associated with comorbidities later in life remains an important question.
New Design of an Electrical Excavator and Its Path Generation for Energy Saving and Obstacle Avoidance
Authors: Ahmadi Khiyavi Omid , Seo Jaho , Lin Xianke
Published: May 2024

This study’s goals are divided into two categories. The first is to design and build an excavator equipped with parallel electrical linear actuators. The second is to generate and test a PSO-based and a PFM-based path for this excavator in order to save energy by reducing energy consumption, improve the digging accuracy by minimizing the deviation between the desired and dug surfaces of the ground, and prevent colliding with subsurface objects. For this purpose, computer vision was employed to improve monitoring and verification. Five types of experiments were carried out in this investigation. The first two and the other three examined the impact of energy conservation in PSO- and PFM-based path generation, respectively. Finally, the results from these experiments were compared to identify and show the effect of optimal path generation.
Graph Analysis of the Visual Cortical Network during Naturalistic Movie Viewing Reveals Increased Integration and Decreased Segregation Following Mild TBI
Authors: Ruiz Tatiana , Brown Shael , Farivar Reza
Published: May 2024

Traditional neuroimaging methods have identified alterations in brain activity patterns following mild traumatic brain injury (mTBI), particularly during rest, complex tasks, and normal vision. However, studies using graph theory to examine brain network changes in mTBI have produced varied results, influenced by the specific networks and task demands analyzed. In our study, we employed functional MRI to observe 17 mTBI patients and 54 healthy individuals as they viewed a simple, non-narrative underwater film, simulating everyday visual tasks. This approach revealed significant mTBI-related changes in network connectivity, efficiency, and organization. Specifically, the mTBI group exhibited higher overall connectivity and local network specialization, suggesting enhanced information integration without overwhelming the brain’s processing capabilities. Conversely, these patients showed reduced network segregation, indicating a less compartmentalized brain function compared to healthy controls. These patterns were consistent across various visual cortex subnetworks, except in primary visual areas. Our findings highlight the potential of using naturalistic stimuli in graph-based neuroimaging to understand brain network alterations in mTBI and possibly other conditions affecting brain integration.
Application of Digital Twin in Electric Vehicle Powertrain: A Review
Authors: Li Xiaokang , Niu Wenxu , Tian Haobin
Published: May 2024

Digital Twin (DT) is widely regarded as a highly promising technology with the potential to revolutionize various industries, making it a key trend in the Industry 4.0 era. In a cost-effective and risk-free setting, digital twins facilitate the interaction and merging of the physical and informational realms. The application of digital twins spans across different sectors, including aerospace, healthcare, smart manufacturing, and smart cities. As electric vehicles have experienced rapid growth, there is a growing demand for the development of innovative technologies. One potential area for digital twins application is within the automotive sector. The powertrain system of electric vehicles (EVs) consists of three parts, power source, power electronic system, and electric motor, which are considered as the core components of electric vehicles. The focus of this paper is to conduct a methodical review regarding the use of digital twins in the powertrain of electric vehicles (EVs). While reviewing the development of digital twin technology, its main application scenarios and its use in electric vehicle powertrains are analysed. Finally, the digital twins currently encounter several challenges that need to be addressed, and so the future development of their application to electric vehicles are summarized.
Artificial intelligence in practice: measuring its medical accuracy in oculoplastics consultations
Authors: Neuhouser Adam J. , Kamboj Alisha , Mokhtarzadeh Ali , Harrison Andrew R.
Published: May 2024

Purpose: The aim of this study was to investigate the medical accuracy of responses produced by Chat Generative Pretrained Transformer 4 (Chat GPT-4) and DALLE-2 in relation to common questions encountered during oculoplastic consultations.
Methods: The 5 most frequently discussed oculoplastic procedures on social media were selected for evaluation using Chat GPT-4 and DALLE-2. Questions were formulated from common patient concerns and inputted into Chat GPT-4, and responses were assessed on a 3-point scale. For procedure imagery, descriptions were submitted to DALLE-2, and the resulted images were graded for anatomical and surgical accuracy. Grading was completed by 5 oculoplastic surgeons through a 110-question survey.
Results: Overall, 87.3% of Chat GPT-4’s responses achieved a score of 2 or 3 points, denoting a good to high level of accuracy. Across all procedures, questions about pain, bruising, procedure risk, and adverse events garnered high scores. Conversely, responses regarding specific case scenarios, procedure longevity, and proceduredefinitions were less accurate. Images produced by DALLE-2-were notably subpar, often failing to accurately depict surgical outcomes and realistic details.
Conclusions: Chat GPT-4 demonstrated a creditable level of accuracy in addressing common oculoplastic procedure concerns. However, its limitations in handling case-based scenarios suggests that it is best suited as a supplementary source of information rather than a primary diagnostic or consultative tool. The current state of medical imagery generated by means of artificial intelligence lacks anatomical accuracy. Significant technological advancements are necessary before such imagery can complement oculoplastic consultations effectively.
Efficient semianalytical investigation of a fractional model describing human cornea shape
Authors: Abukhaled Marwan , Abukhaled Yara
Published: May 2024

Purpose: This study presents a novel application of the semianalytical residual power series method to investigate a one-dimensional fractional anisotropic curvature equation describing the human cornea, the outermost layer of the eye. The fractional boundary value problem, involving the fractional derivative of curvature, poses challenges that conventional methods struggle to address.
Methods: The analytical results are obtained by utilizing the simple and efficient residual power series method. The proposed method is accessible to researchers in all medical fields and is extendable to various models in disease spread and control.
Results: The derived solution is a crucial outcome of this study. Through the application of the proposed method to the corneal shape model, an explicit formula for the curvature profile is obtained. To validate the solution, direct comparisons are made with numerical solutions for the integer case and other analytical solutions available in the literature for the fractional case.
Conclusion: Our findings highlight the potential of the proposed method to significantly contribute to the diagnosis and treatment of various ophthalmological conditions.
RESEARCH ON THE CONSTRUCTION METHOD OF HIGH PRECISION 3D POINT CLOUD MAP FOR AGRICULTURAL ENVIRONMENTS
Authors: ZHAO Bo , LIU Suchun , Zhao Xiufeng , ZHU Licheng , ZHANG Tianfu , HAN Zhenhao , ZHANG Weipeng
Published: May 2024

In agricultural operation scenarios, the diversity of farmland terrain, crops and other forms, as well as uncertain factors such as weather changes and crop growth during agricultural operation, can have an impact on the construction of high-precision maps. To address these challenges and analyze operational scenarios based on the characteristics of agricultural scenarios, this paper proposes a point cloud map construction algorithm for plant point removal and locatability estimation. Based on the existing Simultaneous Localization and Mapping (SLAM) framework, plant point removal and locatability estimation are improved. Firstly, Red, Green, Blue (RGB) images and Near Infrared (NIR) images are fused to identify and remove plant point clouds, preserving effective inter frame matching information, reducing the impact of dynamic points on inter frame matching, and achieving high front-end motion estimation accuracy. Then, the localization estimation method based on learning is used to determine the motion estimation status and determine whether to execute the backend optimization algorithm. Finally, the back-end optimization algorithm based on Factor graph is designed, and the Factor graph, constraint relationship and optimization function are constructed to optimize the pose of all frames. The optimized map construction algorithm reduces the re projection errors between field roads, paths, and crop rows by 10.27%, 20.76%, and 14.36% compared to before optimization. To verify the actual operational effectiveness of the point cloud map construction algorithm, the hardware part of the multi-sensor information collection system was designed, and sensor internal and external parameter calibration were also carried out. A map information collection vehicle was built and field experiments were conducted. The results showed that the positioning error of the point cloud map construction method proposed in this paper is less than 0.5°, and the cumulative error of 30 m translation is less than 12 cm, which meets the actual operational requirements.
SATELLITE IMAGERY USAGE IN AGRICULTURE. CASE STUDY
Authors: MOICEANU Anca Daniela , MOICEANU Georgiana , PARASCHIV Gigel , CRISTEA Mario
Published: May 2024

All sizes of farms can benefit from satellite imagery, not only big producers. When paired with artificial intelligence (AI) and deep machine learning techniques, satellite photography becomes an effective tool for monitoring agricultural conditions and anticipating issues in the field. As a result, using satellite photos to guide crop farming choices can help determine when to apply nutrients and irrigation. This paper focuses on monitoring through satellite sensors with an emphasis on the facilities offered by the European Copernicus Program through Sentinel-2 satellites the crops from a farm from Calarasi County, Borcea commune.
Faktor-Faktor Yang Berhubungan Dengan Stres Kerja Perawat Di Instalasi Gawat Darurat RSUD Ulin Banjarmasin
Authors: Linda Linda
Published: May 2024

Instalasi  Gawat  Darurat  merupakan unit  penting  dalam  operasional  suatu rumah  sakit,  yaitu  Sebagai  pintu masuk pasien dalam  pelayanan  rumah  sakit,  IGD  harus melayani  semua  kasus  yang  masuk  ke rumah  sakit  dan  sesegera  mungkin memberikan  pertolongan  pertama  pada pasien. Perawat dituntut untuk  mampu  bekerjasama  dengan  tim kesehatan, serta pasien  dan  keluarga  pasien  yang berkaitan dengan kondisi kegawatan kasus di  ruang  IGD.  Tuntutan-tuntutan dalam  lingkungan  kegawatdaruratan membuat perawat IGD beresiko terhadap terjadinya  stres. Penelitian menggunakan analitik korelasi dengan desain cross sectional. Jumlah sampel pada penelitian ini ada 34 responden. Pada analisis regresi logistik ganda di dapat 3 variabel yang berhubungan dengan stres kerja yaitu beban kerja, komunikasi interpersonal dan lingkungan kerja. Hasil penelitian lebih lanjut didapatkan faktor yang paling dominan berhubungan dengan stres kerja adalah komunikasi interpersonal (p=0.011) dan OR=69,322. Dalam rangka menurunkan tingkat stres maka perawat IGD hendaknya meningkatkan evaluasi diri, meningkatkan mekanisme koping yang positif dan meningkatkan kualitas teknik komunikasi dalam hubungan interpersonal yang baik, sehingga akan memperlancar pelaksanaan tugas sehari-hari yang pada akhirnya terjalin kerjasama yang baik untuk menyelesaikan tugas.
Effects of propylene glycol in different doses on metabolic parameters in dairy cows
Authors: Şahan Adem , Hanedan Başak
Published: May 2024

In the study, the effects of propylene glycol (PG) drenched in different doses in dairy cows with positive energy balance were evaluated on serum metabolic parameters. Twenty-four Simmental dairy cows in 60-190 days of lactation period with positive energy balance were included to this study. PG was drenched 3 h after morning feeding, at a doses of 300 mL (8 dairy cows) and 500 mL (8 dairy cows), once a day, for 3 days. Eight dairy cows were included for control group. Blood samples were collected once before PG drenching, daily after drenching of PG, and finally on day 4. Serum biochemical parameters were determined. With regard to energy metabolism, glucose concentrations from serum biochemical parameters significantly increased on day 3 in 500 mL PG group compared to control group, and there were not significant changes in BHBA and NEFA concentrations. Decreased urea, increased chloride concentrations were determined with within reference limits. In dairy cows with positive energy balance, 500 mL PG oral drenching had positive effect on energy balance as determined by serum glucose measurements, might not have negative effects on hepatic and renal function, and may cause serum electrolyte changes within reference limits.
Finding the Relationship between Agriculture and Carbon Emissions in Pakistan: An Empirical Investigation
Authors: Ul Hassan Muhammad Iatzaz , Wu Mengyun , Yasir Rasool  , Gates Charles Mawuena
Published: May 2024

Pakistan’s economy depends on the agriculture sector which contributes approximately 25 percent to GDP and 45 percent to total employment. This research work inspects the link between agriculture value-added and carbon emit in Pakistan and other potential indicators for instance gross domestic per capita, Foreign direct investment, total population and resources energy. We retrieved data from the world indicators CD room spanning1988 to 2020 for this study and adopted auto regressive distributive log (ARDL) technique and Stata 18 version were used. The long run results of the study revealed that agricultural value-added, foreign direct investment, non-renewable energy utilization, population and Gross domestic per capita increased environmental deterioration. While consumption of renewable energy upsurge environment sustainability in the region. The outcomes also signpost the presence of bi-directional causality between the given indictors. The outcomes also signpost the presence of bi-directional causality between the given indictors. This study is only limited to only the Pakistan with specific indicators. Based on the empirical evidence, the study support to the agriculture sector through sustainable practices and green technological advancements to the economic growth and renewable resources to promote environmental sustainability in Pakistan.
The Influence of Innovation Strategy on Sustainable Competitive Advantage
Authors: Nuragita Try Ayu , Nursyamsiah Siti
Published: May 2024

This study examines the influence of innovation strategy on sustainable competitive advantage through a functional innovation approach, innovation process, and innovation system. This research utilized survey data conducted on MSMEs in Yogyakarta with a total sample of 95 respondents. In order to answer the research hypothesis, this study employed the Partial Least Square Structural Equation Modeling (PLS-SEM) analysis tool using SmartPLS tools. The results of the study indicate that there is an influence of innovation strategy on the innovation process and system, as well as the influence of the innovation process and system on sustainable competitive advantage. This research has contributed to the development of innovation strategies in building sustainable competitive advantage in MSMEs.
Travel Website
Authors: Kumar Deepak , Kumar Gagan , Kumar Vishal , Mala Gagan
Published: May 2024

Travel Website is an innovative web-based application designed to revolutionize the field of travel planning, which was implemented using a combination of HTML, CSS, JavaScript, and PHP. The uniqueness of the project lies in the fact that the application provides customers with the most relevant information on fares, a vast array of reviews for each unit, and the ability to book without any additional difficulty and hassle. As a result, taking into account the focus on real-time systems and user-generated content, Travel Website undoubtedly surpasses its competitors in terms of modernity and business. The main distinctive characteristic of the application is the ability to collect information on the cost of services from transportation and housing, which allows customers to choose the optimal, profitable journey. On the other hand, the system is algorithm-based to gather the fare information and update it instantly. Thus, users get live notifications whenever fares change are new special offers are available. Finally, the Travel Website’s critical feature is proved based on user-generated content. Users can share their real travel experience, review, and rate transportation. Thus, all users enjoy valuables tips and hints recommended.
Open Dislocated Interphalangeal Fracture of the Thumb in a 16-Year-Old Basketball Player
Authors: Zeddouk Hassan , Saadi Yassine , Boufettal Moncef , Bassir Rida-Allah , Mekkaoui Jalal , reda Fekhaoui Mohammed , Berrada Mohammed Saleh , Kharmaz Mohammed
Published: May 2024

Phalangeal dislocation fractures of the hand are common in the sports world especially contact sports and ball sports. Open ones are less common. In this article we report a case of a 16-year-old young basketball player who injured her right thumb during a practice. Clinical and radiological examinations showed an open phalangeal dislocation fracture of the thumb. Management consisted of immediate reduction, abundant washing and finger splint for 4 weeks after X-rays showed anatomical reduction. Short, medium and long term clinical and radiological examinations showed good evolution. At our last follow up (1.5 years) our patient had regained full use of her hand in both daily and sporting activities. The purpose of this study is to encourage non operative treatment in dislocated fractured fingers when treated early if the initial external reduction is anatomical, and to show the need for further studies in similar cases in the sport world.
ASPIRIN IN CAD: Is it Still the King of the Ring in 2024?
Authors: Bouraghda MA. , Takdemt W , Bououdina Y , Bouzid MA.
Published: May 2024

With its 3,500-year history, aspirin is one of the most widely used medicines in the world. For a very long time, its place in secondary and sometimes even primary cardiovascular prevention was indisputable. However, a growing body of clinical data is calling this dogma into question. It is therefore necessary to reassess its efficacy and, above all, its safety in certain indications, such as primary cardiovascular prevention in at-risk populations, anti-platelet monotherapy following DES implantation, and post-acute coronary syndrome.
Correlation of Ultrasound Guided (USG) Fine Needle Aspiration Cytology (FNAC) With Postoperative Histopathology in the Diagnosis of Thyroid Swelling
Authors: Rahman Md. Mostafijur , Sultan Saad , Islam Md. Ariful , Quddus Abdul , Tarafder Kamrul Hasan
Published: May 2024

Background: Thyroid swelling is a common problem in Bangladesh. Early and systematic evaluation of a nodular thyroid swelling is necessary as it is a frequent presentation of thyroid neoplasia. USG Guided Fine needle aspiration cytology (FNAC) is one of the diagnostic tools for early evaluation of thyroid nodules. USG Guided FNAC is considered as a cost-effective, simple, minimally invasive and easily repeatable procedure for preoperative screening in the diagnosis for most of the thyroid lesions. The objective of this study is to determine the sensitivity and specificity of USG Guided fine needle aspiration cytology (FNAC) and compare the efficacy with histopathology in diagnosis of thyroid swellings. Objective: To evaluate the sensitivity and specificity of USG Guided fine needle aspiration cytology (FNAC) and histopathology for the diagnosis of thyroid swelling. Method: This Observational Prospective Study was performed in the department of Otolaryngology & Head Neck Surgery, Dhaka Medical College Hospital. Dhaka over 6 month’s duration from January 2019-June 2019. Total 50 patients with thyroid swelling was selected after taking informed written consent and fulfilling the inclusion criteria. Smears was taken by standard procedure and then was stained with papanicolaou stain and haematoxylin and eosine stain. The smears was classified into categories like benign, indeterminate, malignant and unsatisfactory. Sensitivity, specificity, positive and negative predictive value and accuracy of USG Guided FNAC was calculated and compared to already available data. Appropriate statistical analysis was done to make comparison between final histopathological findings with initial USG Guided FNAC findings. Result: During the study period a total 73 were found eligible for USG Guided FNAC. Most of the patients (52%) were from 20-39 years age group. Among them 67.12% were female and rest (32.87%) were male. In this government hospital 75.34% were from low income group. ......
The Study of Body Condition Score and Macro Minerals on Fertile and Repeat Breeding Cattle in Ngaglik Sub-District
Authors: Datrianto Dwi Sunu , Indarjulianto Soedarmanto , Nururrozi Alfarisa , Paryuni Alsi Dara , Jr Topas Wicaksono Priyo , Adi Yosua Kristian , Egan Azzahra Fairuz Vervena
Published: May 2024

Beef is a source of animal protein in demand by the Indonesians. The development of cattle breeding in Indonesia needs to grow. One factor that causes the stagnation of cattle breeding is reproductive disorders. A reproductive disorder that local farmers in Indonesia often find is repeat breeding. This study aimed to know the Body Condition Score (BCS), Sodium (Na), and Chloride (Cl) between fertile and repeat-breeding cattle. This study used ten Simmental-PO cattle, and the research was conducted in Ngaglik Sub-District, Sleman City, Special Region of Yogyakarta Province. Cattle were divided into two groups, with five cattle in each group. Anamnesis examinations among farmers and reproduction records tests aimed to determine the fertile and repeat breeding cattle. Furthermore, body condition scoring is achieved by examining and palpating the costume and vertebrae. Blood samples were collected to determine the sodium and chlorine levels. Body Condition Score parameters among cattle were analyzed descriptively, and Na and Cl levels were analyzed using an independent T-test. The results of the BCS study on fertile cattle are 3,3 on average, and repeat breeding cattle are 2,5 on average. In addition, the results of the Na study on fertile cattle were 132.7±3.8, and repeat-breeding cattle were 131.6±2.5 (P>0.05). The results of the Cl study on productive cattle were 91.7±3.0 and repeat-breeding cattle 89.3±4.7 (P>0.05). The conclusion is that BCS is fertile range 2-3 and repeats breeding range 3-4. In conclusion, Na and Cl have no significant differences in productive and repeat-breeding cattle.
PENGARUH UKURAN PERUSAHAAN, ROA DAN LEVERAGE PADA TARIF PAJAK EFEKTIF PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI PADA 2017-2020 (SUBSEKTOR CONSUMER GOODS)
Authors: Tarigan Krisnawati , Octavianus Andrew Liejaya
Published: May 2024

The study aims to test whether Company Size, Return on Asset, and Leverage affect Effective Tax Rates. The data used is secondary data or derived from the financial statements of manufacturing companies registered with the IDX for the period 2017-2020. Retrieval techniques use purposive sampling techniques. The number of samples processed is 32 companies with overall observation data reaching 128 samples. The data was analyzed using multiple linear regression analysis and processed using the SPSS version 24 program. The results showed that the Size of the Company had a positive but insignificant effect on the effective tax rate, the return on asset negatively and significantly on the effective tax rate, and the leverage had a significant positive effect on the effective tax rate.
Keywords: Company Size, Return on Asset, Leverage, Effective Tax Rate.
Analysis of Factors Affecting Firm Performance Moderated by Competitive Strategies
Authors: Immanuel Caroline , Prima Dewi Sofia
Published: May 2024

The purpose of this research was to obtain evidence on the effect of financial leverage and components of intellectual capital (human capital efficiency, structural capital efficiency, capital employed efficiency) on firm performance with competitive strategies as moderation in manufacturing companies listed in Indonesian Stock Exchange during three years. The sample was selected using the cluster sampling method amounted to 27 companies. Data processing methods were performed using EViews. The results showed that financial leverage, human capital efficiency, and structural capital efficiency have an influence on firm performance, while capital employed efficiency and financial leverage moderated by competitive strategies have no influence on firm performance.
 Keywords: Financial Leverage; Intellectual Capital; Competitive Strategies; Firm Performance
Analisis Kinerja Finansial Pemerintah Daerah Provinsi DKI Jakarta Periode 2017-2021
Authors: Santosa Stellavia Claudia , Pandowo Andrew , Munandar Agus
Published: May 2024

This research aims to analyze the financial performance of DKI Jakarta by the government from 2017 to 2021. Research performance is conducted by calculating analysis ratio with five measurements namely independency ratio, efficiency ratio, effectiveness ratio, growth ratio and degree of decentralization. Results of this research show that there is high independence of the DKI Jakarta government, subsequently the government is rated effective in realizing regional revenue, also having significant growth and positive financial efficiency by the government.
Keywords: Decentralization, Financial Performance, SiLPA
Latest Trend and Perspective of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) as a Novel Nomenclature
Authors: Bando Hiroshi
Published: May 2024

Recently, the medical term for nonalcoholic fatty liver disease (NAFLD) has been changed to a novel nomenclature: metabolic dysfunction-associated steatotic liver disease (MASLD). The latest report shows analyses of the National Health and Nutrition Examination Survey (NHANES III) using the fibrosis-4 index (FIB-4) and enhanced liver fibrosis (ELF). Among 6429 NAFLD cases, 99% met MASLD criteria. In another study with 4286 cases, 99% of steatosis cases met the MASLD definition, and 95.4% met the metabolic dysfunction-associated fatty liver disease (MAFLD) definition. Several biomarkers show a relationship with MASLD/MAFLD, such as BMI, T2D, HOMA-IR, central obesity, waist circumference, and CKD.
Panorama da Tireoidite de Hashimoto: bases patogênicas, diagnósticas e terapêuticas
Authors: Acioli Lima de França Daniella , Vytor Cardoso Nobre Paulo , Luisa Vieira Cuyabano Leite Maria , Alves de Matos Barbosa Flavia , Farias Mota Marcos , Victor Nunes Cadete João , José Fernandes de Souza Vieira Henrique , Patrícia Acioli Lima de França Lara , Ester Gonçalves Ferreira Cavalcanti Manso Maria , Das Neves Pulcino Tarciany , Lages da Resurreição Fernando , Elves Vieira de Oliveira Junior Alan , Thamyres Barbosa Ferreira da Silva Isadora , Beatriz Soares Tojal de Barros Lima Ana
Published: May 2024

Introdução: A tireoidite de Hashimoto (HT) é uma doença autoimune que afeta a glândula tireoide, caracterizada pela progressiva inflamação e destruição do tecido tireoidiano, desencadeada pela resposta autoimune, que resulta na produção de autoanticorpos, como os anticorpos antitireoglobulina e antitireoperoxidase. Objetivo: Avaliar a patogênese, o diagnóstico e o manejo da Tireoidite de Hashimoto. Metodologia: Trata-se de uma revisão bibliográfica que incluiu artigos originais e revisões sistemáticas em inglês e português, que abordaram os aspectos patogênicos, diagnósticos e terapêuticos da HT, publicados entre 2014 e 2024, selecionados nas bases de dados PubMed, Scopus e SciELO. Após a seleção criteriosa, foram escolhidos 28 artigos para compor esta revisão bibliográfica. Resultados: A patogênese da TH apresenta múltiplos aspectos relevantes, como a anomalia das células T reguladoras, a atividade exacerbada das células Th17 e a expressão aumentada de componentes inflamassômicos e citocinas pró-inflamatórias. O diagnóstico é realizado principalmente pela dosagem de TSH, T4 livre e Anti-TPO, porém pode ser necessário outros exames complementares. O manejo é principalmente associado à reposição hormonal em pacientes com hipotireiodismo. Considerações: A TH é uma condição complexa, incluindo múltiplos mecanismos patogênicos que precisam ser mais elucidados. O diagnóstico é baseado principalmente na dosagem sérica de alguns compostos. As intervenções farmacológicas são associadas ao uso exógeno do hormônio tireoidiano e a cirurgia em alguns casos específicos.
SUFFICIENCY OF INSTRUCTIONAL RESOURCES AND PERFORMANCE OUTCOMES OF TECHNOLOGY AND LIVELIHOOD EDUCATION STUDENTS
Authors: Charity T. Embodo  , Randy B. Alonzo
Published: May 2024

In the landscape of secondary education, Technology and Livelihood Education (TLE) stands as a critical component, offering students a pathway to develop skills essential for personal and collective growth, particularly in scenarios where access to higher education is limited. The study was conducted in the Division of Panabo City, involving 200 TLE teachers explored the relationship between instructional resource sufficiency and student performance outcomes. Findings revealed a moderate extent of sufficiency in instructional resources, with certain dimensions consistently evident while others showed occasional presence. Similarly, student performance outcomes were deemed satisfactory, though with variations across different dimensions. The study underscored a significant correlation between the sufficiency of instructional resources and student performance outcomes, highlighting the critical role of resource availability in shaping student achievement. Notably, all domains of instructional resources, including textbooks, laboratory equipment, technology, physical facilities, and human resources, demonstrated a significant influence on student performance. This emphasizes the importance of targeted interventions to improve resource sufficiency and ensure a conducive learning environment for students. Recommendations were put forth to address identified areas of moderate sufficiency, advocate for resource allocation, foster collaboration among stakeholders, and enhance teacher professional development.
KEYWORDS: Instructional resources; performance outcomes; Division of Panabo City
MANAGEMENT BEHAVIOR OF SCHOOL HEADS AND PSYCHOLOGICAL CAPITAL OF PUBLIC SECONDARY TEACHERS IN PANABO CITY DIVISION
Authors: Dina S. Tiempo  , Ronaldo L. Serras
Published: May 2024

The study explored the relationship between management behavior of school heads and psychological capital of teachers in public secondary schools of Panabo City Division. Also, it investigated the association of the involved variables and the domains of management behavior of school heads that significantly influenced psychological capital of teachers. With the use of probability sampling, 150 secondary teachers in the public schools were selected as the respondents. Utilizing the descriptive-correlational survey method, the data collated were analyzed through the use of Mean, Product-Moment correlation and Regression Analysis. Results revealed that there was a very extensive management behavior of school heads and a very extensive psychological capital of teachers. Furthermore, there was a significant relationship between the management behavior of school heads and psychological capital of teachers. Moreover, all domains of management behavior of school heads were found to have significantly influenced on the psychological capital of teachers. Based on the findings, it was further suggested that higher officials in the Department of Education may identify means on how to help the school heads in strengthening their management behavior to help teachers reinforce their psychological capital.
KEYWORDS: Management behavior, psychological capital, descriptive correlation, Panabo City Division, Philippines
Novel patient-specific gingival soft-tissue expander development for large bone defects using silicone 3D-printing technology
Authors: Huang Tzu-Huan , Huang Shao-Fu , Yu Lu-Yi , Lo Chun-Liang , Chang Yu-Ping , Lin Chun-Li
Published: May 2024

The current hydrogel self-inflating expander is limited by its volume and linear expansion rate, making it unsuitable for correcting patient-specific large mandibular bone defects in soft-tissue surgeries. This study devised a novel approach for crafting patient-specific gingival tissue expanders for large mandibular bone defects by employing silicone 3D-printing technology. The biocompatible and swellable polymer tablet was compressed and placed into a 3D-printed silicone membrane to evaluate its expansion capability. Two patient-specific large left and right mandibular bone defects with complex geometries were selected to generate defect expander models in a computer-aided design (CAD) software. The swellable tablets were enveloped in the 3D-printed silicone membranes to form soft-tissue expanders, which were then immersed in phosphate-buffered saline (PBS) for 6 weeks to observe their expansion. Results demonstrated that a slot-shaped silicone soft-tissue tablet attained an expansion volume of 1960 mm³. A fourth-degree polynomial fitting curve illustrated slower expansion rates in the initial 2 weeks and achieved complete expansion in about 6 weeks. Patient-specific silicone expander testing indicated less than 2% error in the average expanded volumes of compared to CAD models. The cross-sectional profile of the soft-tissue expanders closely resembled the CAD model. This study demonstrated that biocompatible polymer could be utilized as swellable tablet material and enveloped within a 3D-printed silicone membrane to generate a novel soft-tissue expander that adhered to clinical standards. Additionally, the study validated the feasibility of expanding patient-specific silicone expanders within 6 weeks for repairing large left and right mandibular bone defects.
Effects of Ca2+/Mg2+ ions in recycled water on the reverse flotation properties of iron oxides
Authors: Tang Min , Wu Yan , Fu Jiahao
Published: May 2024

Water quality, particularly hardness, plays an important role in affecting the floatability of minerals as it interferes with the chemical/electro-chemical characteristics of mineral surfaces and their interactions with flotation reagents. It could become unpredictable when water sources characterized by different calcium or magnesium ion distributions were involved. This study aimed to identify the role of Ca2+/Mg2+ ions in the recycled water on the cationic reverse flotation selectivity of iron oxides through a series of bench/micro flotation tests, zeta potential, powder contact angle, and Fourier Transform Infrared (FTIR), etc. The results pointed out that the use of recycled tailing water deteriorates the flotation selectivity and dilutes the concentrates. This can be largely attributed to the presence of Ca2+ ions at higher concentrations as they induce a drop in the Fe recovery and an increase in SiO2 content while an increase in the content of Mg2+ ions seems to have little effect on the quality of concentrate. As evidenced by the data from micro-flotation, powder contact angle, zeta potentials, and FTIR, a hydrophilic colloidal layer formed by Ca-based hydrolyzed compounds, such as Ca(OH)+ or, CaCO3(s), etc., on quartz could change its zeta potentials and disturb its interactions with a cationic collector. They also play a role in weakening the flocculation of starch on hematite probably by pre-locking the acidic groups on the starch remnants and contracting their configurations, thus preventing their adsorption on mineral surfaces. However, magnesium ions seem to be beneficial to in strengthening the flocculation of starch on hematite as magnesium-based species could act as adsorption bridges of between starch and mineral surfaces.
A Case Report of 80-Year-Old Male with Total Atrioventricular Block, Acute Decompensated Heart Failure, and Non-ST-Elevation Myocardial Infarction Very High Risk: A Complicated Case in Limited Resources Setting
Authors: Wulandari Ni Kadek Putri , Putu Sukma Parahita Aditya
Published: May 2024

Background: Cardiovascular disease is still a major problem globally, with high morbidity and mortality rates. The progression of cardiovascular disease is so dynamic that it can leave the patient in a terminal condition. Given the high mortality and morbidity accompanied by rapid disease progression, understanding the appropriate management of each patient with comorbid heart disease is very important.
Case presentation: We report an 80-year-old male with TAVB (Total Atrioventricular Block), ADHF (Acute Decompensated Heart Failure), and NSTEMI (Non-ST-Elevation Myocardial Infarction). The patient was treated and stabilized intensively in our center based on protocol. Due to the rapid progression of the disease, we referred the patient to the tertiary hospital in Bali for further advanced treatment.
Conclusion: The mortality rate in cases of cardiovascular diseases is relatively high, requiring rapid and adequate treatment to provide better clinical outcomes.
Similarity Measures between Buying and Selling Prices of Various Exchange Rates with the inclusion of Multidimensionality and Multicollinearity
Authors: Ng Dennis Wen Wei , Chang Yun Fah , Sivanandan Premagowrie , Ng Wei Shean
Published: May 2024

This paper introduces a new statistical model, the multidimensional measurement error model with multicollinearity, to study the relationship between buying and selling prices of foreign exchange rates of various currencies. Such a model is needed due to the possible rise in multidimensionality and multicollinearity issues that may occur due to the movement of the financial markets towards stock market integration of various countries since the occurrences of the financial crisis as well as the part result of globalization. As this integration involves the participation of various countries, it will affect the foreign exchange rate. Hence, the analyses are performed on seven currencies against the Malaysian Ringgit where four models’ performances are compared. From this research, it can be concluded that the proposed model comparatively performs better than the other models in representing the relationship of the stationary prices and performs as well as existing models towards non-stationary prices. It can also be seen that the Japanese Yen is the currency that has the strongest influence and closer similar trends towards other currencies while the Great British Pound showed otherwise.
Tecnotimistas x tecnofóbicos
Authors: Barão Marques Filho Lourival
Published: May 2024

Contextualização: As novas tecnologias originadas na e pela quarta revolução industrial extinguirão ou reduzirão substancialmente os postos de trabalho em virtude da automação e da inteligência artificial?
Objetivo: O artigo tem por finalidade investigar os impactos das revoluções industriais no mundo do trabalho. Inicialmente, examinam-se o formato e as consequências das três primeiras revoluções industriais para, então, verticalizar o estudo sobre a quarta revolução industrial. Identifica-se a existência de duas correntes: tecnotimistas x tecnofóbicos, o que torna essencial analisar o estado da arte em ambas visões.
Método: Utiliza-se o método dedutivo para buscar responder o problema proposto, valendo-se da literatura produzida por sociólogos, economistas e historiadores.
Resultados: O artigo argumenta que tecnologia e emprego não são excludentes; ao revés, são complementares. Em todos os momentos em que houve uma substancial alteração nos modos de produção sempre houve o receio da extinção do trabalho humano. Mas, constatou-se que no decorrer dos dois últimos séculos a tecnologia foi uma fomentadora e criadora de novas formas de prestação de serviços e não uma eliminadora de empregos. O impacto emocional, social e sensitivo da inteligência artificial, que parece tornar tudo obsoleto e dispensável, também ocorreu quando a máquina a vapor, o motor a combustão ou o computador foram criados. Porém, o que se viu foi o aumento quantitativo e, depois, qualitativo dos trabalhos gerados e desenvolvidos.
Sistem Pendukung Keputusan Pemilihan Pupuk Efektif Untuk Budidaya Bawang Merah di Kecamatan Brebes Menggunakan Metode Additive Ratio Asessment (ARAS)
Authors: Nuriman Nuriman , Darmawan Erlan , Muhsin Muhsin
Published: May 2024

Tanaman bawang merah merupakan komoditas agribisnis dan jenis tanaman hortikultura yang memiliki nilai ekonomis tinggi. Kabupaten Brebes merupakan salah satu daerah penghasil bawang merah yang cukup signifikan di Indonesia. Berdasarkan hasil wawancara dengan petani pada saat sensus pertanian 2023 ditemukan permasalahan, yaitu petani cenderung lebih suka melakukan eksperimen saat pemilihan pupuk, sehingga membutuhkan waktu yang lama dan pengeluaran menjadi lebih banyak. Tujuan penelitian ini yaitu untuk membangun sistem pendukung keputusan menggunakan metode Aditive Ratio Assesment (ARAS) dan perankingan alternatif pupuk berdasarkan kriteria harga, dosis, umur dan kandungan pupuk. Tahapan memulai sistem perhitungan metode ARAS dengan memasukkan kriteria, alternatif, atribut dan bobot pada menu kriteria. Selanjutnya input sub nilai kriteria dan input data awal perhitungan pada menu alternatif. Sehingga menu perhitungan tampil. Hasil dari sistem perhitungan metode ARAS yaitu perankingan dari 8 alternatif: NPK Mutiara, KCI, SP-36, ZA, DAP (Phospat), Urea, Kamas, NPK Ponska. Berdasarkan kriteria pemilihan pupuk, dari 8 alternatif itu NPK mutiara berada di urutan pertama dengan nilai ki 0,6059, urutan kedua KCI dengan nilai ki 0.5312 dan urutan ketiga DAP(Phospat) dengan nilai 0,5014.
Pendampingan UMKM di Kota Bandung pada Aspek Pemasaran, Operasional, dan Keuangan
Authors: Debby Teresia , Iskandarsyah Triyana , Tjandraningsih Indrasari , Rismawati  , Assaf Rizka Aula , Wicaksono Ignatius Bryan Abimanyu
Published: May 2024

Mahasiswa program studi sarjana Manajemen Fakultas Ekonomi Universitas Katolik Parahyangan Bandung melalui mata kuliah wajib Pelayanan Kepada Masyarakat melakukan pendampingan terhadap UMKM di kota Bandung yang bertujuan untuk membantu menyelesaikan permasalahan yang dihadapi oleh para pemilik.  Metode yang digunakan pada kegiatan pengabdian ini adalah service learning. Di mana service learning merupakan sebuah metode pembelajaran yang memberikan penekanan pada penerapan pengetahuan perkuliahan ditengah-tengah masyarakat atau komunitas sekaligus berinteraksi dengan masyarakat atau komunitas serta menjadi solusi terhadap persoalan-persoalan yang dihadapi oleh masyarakat atau komunitas, sehingga mampu menerapkan secara nyata peran mahasiswa dan kampus dalam melakukan pengabdian kepada masyarakat. Setelah dilakukan baseline assessment, permasalahan utama yang dihadapi usaha mikro dan kecil meliputi masalah pemasaran, operasional dan pencatatan keuangan. Dalam masa pendampingan selama dua belas minggu, sebanyak tiga puluh enam unit usaha mikro dan kecil mendapatkan pengetahuan dan dapat menerapkan hasil pendampingan yang diberikan terkait pemanfaatan media sosial dan e-commerce untuk promosi, peningkatan kesadaran K3 dan pemahaman terhadap aspek-aspek keuangan yang meliputi penghitungan harga pokok penjualan, pencatatan keuangan, serta membuat neraca laba rugi.
Pengembangan dan Pelatihan Digitalisasi E-Commerce UMKM Bangka
Authors: Afriansyah Riki , Setya Pratama Muhammad , Fitriyani Agus , Ramadhan Muhammad , Ventani Embun
Published: May 2024

Usaha Mikro, Kecil dan Menengah (UMKM) Kabupaten Bangka masih melakukan transaksi penjualan dan pemasaran produk secara tradisional. Kegiatan Pengembangan dan Pelatihan Digitalisasi E-Commerce pada UMKM Bangka bertujuan meningkatkan daya saing dan kemampuan dalam memasarkan produk melalui platform e-commerce khusus di Kabupaten Bangka. Sistem informasi e-commerce diperlukan agar dapat membantu UMKM dalam menjalankan aktivitas transaksi penjualan. Selain itu, DISNAKER PERINDAG Kabupaten Bangka dapat memonitor transaksi penjualan tersebut. Fitur E-commerce memungkinkan UMKM untuk mengelola transaksi penjualan secara online maupun onsite ketika ada pelanggan yang membeli produk di tempat penjualan. Pelaksanaan kegiatan pengabdian kepada masyarakat dimulai dari melakukan pembuatan sistem e-commerce hingga memberikan pelatihan dan sosialisasi kepada pengguna sistem. Dari hasil kegiatan pelatihan diperoleh hasil survei menunjukkan bahwa 91.47% responden merasa sistem mudah digunakan, 89.24% menyatakan sistem memberikan manfaat, dan 90.84% berkeinginan untuk mengimplementasikan sistem.
DERRAME DE PETRÓLEO NA COSTA DO BRASIL (2019-2020): CARACTERIZAÇÃO E RISCOS ASSOCIADOS
Authors: Souza Thiago de Aguiar , Sotão-Neto Basílio Magno Tavares , Combi Tatiane
Published: May 2024

O petróleo é uma mistura complexa formada por compostos orgânicos e inorgânicos em proporções variáveis. Dentre os principais grupos de compostos orgânicos encontrados no petróleo bruto estão os hidrocarbonetos policíclicos aromáticos (HPAs), que são substâncias amplamente difundidas no meio ambiente, podendo ser encontrados no solo, água, ar e biota. A preocupação ambiental relacionada aos HPAs se deve ao seu potencial carcinogênico e toxicidade à biota aquática, podendo representar riscos à saúde animal e humana, entre o final de agosto de 2019 e março de 2020 ocorreu um derrame de óleo que atingiu a costa brasileira, principalmente a região nordeste o que já é considerado o maior acidente ambiental ocorrido em regiões tropicais.