bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanisms of chronic postsurgical pain
Authors: Tassou Adrien , Richebe Philippe , Rivat Cyril
Published: February 2025

Chronic pain after surgery, also known as chronic postsurgical pain (CPSP), is recognized as a significant public health issue with serious medical and economic consequences. Current research on CPSP underscores the significant roles of both peripheral and central sensitization in pain development and maintenance. Peripheral sensitization occurs at the site of injury, through the hyperexcitability of nerve fibers due to surgical damage and the release of inflammatory mediators. This leads to increased expression of pronociceptive ion channels and receptors, such as transient receptor potential and acid-sensing ion channels (ASIC), enhancing pain signal transmission. Central sensitization involves long-term changes in the central nervous system, particularly in the spinal cord. In this context, sensitized spinal neurons become more responsive to pain signals, driven by continuous nociceptive input from the periphery, which results in an enhanced pain response characterized by hyperalgesia and/or allodynia. Key players in this process include N-methyl-D-aspartate receptor and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, along with proinflammatory cytokines and chemokines released by activated glia. These glial cells release substances that further increase neuronal excitability, maintaining the sensitized state and contributing to persistent pain. The activation of antinociceptive systems is required for the resolution of pain after surgery, and default in these systems may also be considered as an important component of CPSP. In this review, we will examine the clinical factors underlying CPSP in patients and the mechanisms previously established in preclinical models of CPSP that may explain how acute postoperative pain may transform into chronic pain in patients.
In-situ shear modulus reduction with strain in stiff fissured clays and weathered mudstones
Authors: Briggs Kevin Mark , Trinidad González Yuderka , Meijer Gerrit Johannes , Powrie William , Butler Simon , Sartain Nick
Published: February 2025

The non-linear stress-strain behaviour of stiff clays and weak rocks at small and medium strains may be a critical consideration in the design of geotechnical structures. Empirical methods have been developed for estimating the maximum shear modulus and the normalised shear modulus reduction with strain of fine-grained soils. These are usually expressed as functions of the void ratio (or specific volume) and average effective (confining) stress, based on results from laboratory tests. However, the fidelity of these equations has not been widely evaluated in-situ.
This paper describes the use of in-situ measurements from an instrumented embankment to calculate the operational in-situ shear modulus of the underlying stiff clays and weathered mudstones at medium and large strains. It is shown that the shear modulus at very small strain of the weathered clays increased linearly with depth, consistent with empirical equations. The gradient of the normalised, non-linear stiffnesses of the clays were comparable with those measured in laboratory tests of fine-grained soils, at a range of strains. However, the values for the reference strain, where the maximum shear modulus reduces by 50%, were lower than was predicted by the empirical equations.
Evaluation of Sinorhizobium meliloti strains and commercial rhizobial inoculants for fenugreek production in Canada
Authors: Wickramarathna Aruna , Knight J. Diane , Greenshields Dave
Published: February 2025

Fenugreek (Trigonella foenum-graecum L.) is a versatile annual legume valued for its nutritional, medicinal, and agricultural uses. Like other legumes, fenugreek can conduct biological nitrogen fixation (BNF). Because fenugreek lacks a dedicated commercial rhizobial inoculant, this study aimed to evaluate the effectiveness of six commercial rhizobial inoculants registered for alfalfa and sweet clover, alongside fifteen Sinorhizobium meliloti strains, on two fenugreek varieties, CDC Canafen and Fenucold. Using laboratory inoculation tests and greenhouse experiments, the symbiotic potential of these products and strains was assessed through nodule formation, BNF, dry matter yield, and the amount of nitrogen fixed. There was variability in symbiotic performance across the strain-variety combinations, with the commercial inoculant RIZOLIQ TOP-Alfalfa and the pure strains USDA1811 and USDA1150 demonstrating superior nodulation, % nitrogen derived from the atmosphere (%Ndfa), and dry matter production. CDC Canafen generally exhibited greater nitrogen fixation compared to Fenucold, and the varieties could fix up to 58% and 47% of their required nitrogen, respectively. The study identifies a registered commercial inoculant that can be used on common fenugreek varieties grown in Canada and shows the potential of other S. meliloti strains for future improvements to inoculant offerings.
Construction of a Compton camera-equipped robotic system capable of moving autonomously towards the radiation source
Authors: Sato Y. , Kakuto T. , Tanaka T. , Shimano H.
Published: February 2025

In decommissioning the Fukushima Daiichi Nuclear Power Station, understanding the distribution of radioactive substances is crucial to developing detailed decontamination plans and minimizing worker exposure. In this study, an autonomous mobile radiation source detection system based on a mecanum wheel robot equipped with a Compton camera was constructed. The Compton camera visualizes the radiation source, and software embedded in the robot system reads the results to recognize the radiation source and move the robot toward it. If the robot’s depth camera detects an obstacle while moving, it changes direction, visualizes the radiation source again using the Compton camera, and repeats moving the robot toward the radiation source. Furthermore, two demonstration tests were conducted in the laboratory using a 137Cs radiation source to confirm that the robot can reach it where there are obstacles or a narrow region. We have also summarized issues that must be identified to apply this system to actual decommissioning sites.
Nonlinear parametric generation of optical vortices and their propagation in graphene quantum dots
Authors: Alalaq Iman Samir , Rajiv Asha , Ariffin I. A. , Darwish Nashwan Salah Aldeen , Thajeel Sadeq Khudhur , Bahair Hala , Singh Ashish , Sharma Aditi , Hameed Safaa Mustafa , Altimari Usama S. , Hamoodah Zainab Jamal , Alhadrawi Merwa
Published: February 2025

In this paper, we investigate the propagation of optical vortices carrying orbital angular momentum in a coherently prepared graphene quantum dot (GQD) system. Using the Maxwell–Bloch equations and assuming weak light–matter interaction, we examine two key scenarios. The first scenario involves the transfer of optical vortices through nonlinear parametric process, starting with one vortex beam absent and then generated during its interaction with the GQD system. We analyze how various system parameters affect vortex conversion efficiency and the matching of optical vortices. Our results reveal that vortex conversion efficiency is significantly influenced by detuning and incoherent pumping, with notable efficiency and steady-state intensity achieved when these parameters are properly manipulated. In the second scenario, where both vortex beams are initially present, we explore their propagation within the GQD medium. In particular, we observe that when both beams are resonant and incoherent pumping is applied, they quickly stabilize and perfectly match over short propagation distances. Conversely, when both beams are nonresonant, they exhibit oscillatory decay in intensity, preventing them from achieving a steady-state match and leading to absorption by the GQD medium. This study enhances our understanding of vortex beam dynamics in GQD systems and provides insights into optimizing vortex beam transfer for high-dimensional quantum information processing applications.
Diagnostic tomography of applied holography
Authors: Khveshchenko D. V.
Published: February 2025

The single-particle behavior in [Formula: see text]-dimensional Fermi gases with a large number N of species and strong short-range s-wave scattering is studied in the (effectively) [Formula: see text] ‘tomographic’ framework and is shown to demonstrate certain features of a pseudo-holographic correspondence with the [Formula: see text] gravity of the [Formula: see text] type. However, due to the intrinsically topological nature of the latter theory, its dynamics reduces to a purely boundary one and so, akin to its [Formula: see text] counterpart, this formal correspondence neither represents a genuine case of, nor endorses the hypothetical holographic duality between pairs of fully dynamical systems defined in different dimensions.
On Leray’s blow-up condition
Authors: Schonbek Maria E. , Schonbek Tomas P.
Published: February 2025

In his ground breaking paper [4], Leray proves that if the velocity [Formula: see text] is a smooth solution to the 3-dimensional, incompressible, Navier–Stokes equations, that blows up in finite time [Formula: see text], then [Formula: see text]. This provides a lower bound for possible blowouts of solutions to the Navier–Stokes equations. The possibility of a blowout occurring at this minimal level was explored in [3, 5]. This paper supplements and extends these results, looking in more detail at the concept of ancient solutions.
The Genesis and Significance of Pyrite in the Ordovician Majiagou Formation in the Central and Eastern Ordos Basin
Authors: Qiu Wanliu , Zhang Dongdong , Chen Xiaoyan , Liu Wenhui , Wang Xiaofeng , Zhang Tao , Luo Houyong , Zhang Qian , Feng Danting
Published: February 2025

The geochemical data of the gas sourced from the Majiagou Formation indicate low organic content and high thermal maturity, which make the evaluation of the hydrocarbon generative potential difficult. However, the low organic abundance and high thermal maturity of the Majiagou Formation make it difficult to evaluate its hydrocarbon generation potential. The Study of the genesis of pyrite can provide a better understanding of a source rock depositional environment and its evolution. In this paper, we report a significant amount of pyrite linked to the hydrocarbon source in the Majiagou Formation. Light and electron microscopy were used to observe the morphology pyrite while sulfur, carbon, and oxygen isotope were used to investigate the geochemical characteristics of pyrite and the surrounding rock matrix. The results showed that macroscopic stellate pyrite filled cracks and is found in veins or along the laminar surface, as well as agglomerated pyrite; microscopically, pyrite is dominated by autotypic pyrite in the form of cubes, pentagonal dodecahedrons, and columns. The

δ

34
S
CDT
ranged from 4.6‰ to 27.5‰,

δ

13
C
PDB
values ranged from −3.4‰ to −2.3‰, and

δ

18
O
PDB
values ranged from −10.5‰ to −7.3‰. Our findings, combined with the geological background and thermal history of the region, the pyrite in the Majiagou Formation was formed by thermochemical sulfate reduction. Indicating that large-scale hydrocarbon generation events have occurred. The rocks of the Majiagou Formation had the ability to generate hydrocarbons. The research can be utilized as supporting material for the exploration and development of natural gas fields in the Ordos Basin.
Whom do Explanations Serve? A Systematic Literature Survey of User Characteristics in Explainable Recommender Systems Evaluation
Authors: Wardatzky Kathrin , Inel Oana , Rossetto Luca , Bernstein Abraham
Published: February 2025

Adding explanations to recommender systems is said to have multiple benefits, such as increasing user trust or system transparency. Previous work from other application areas suggests that specific user characteristics impact the users’ perception of the explanation. However, we rarely find this type of evaluation for recommender systems explanations. This paper addresses this gap by surveying 124 papers in which recommender systems explanations were evaluated in user studies. We analyzed their participant descriptions and study results where the impact of user characteristics on the explanation effects was measured. Our findings suggest that the results from the surveyed studies predominantly cover specific users who do not necessarily represent the users of recommender systems in the evaluation domain. This may seriously hamper the generalizability of any insights we may gain from current studies on explanations in recommender systems. We further find inconsistencies in the data reporting, which impacts the reproducibility of the reported results. Hence, we recommend actions to move toward a more inclusive and reproducible evaluation.
Asymmetric Electrode Ionomers Based on Polydiallyldimethylammonium Block Copolymers for Enhanced Performance in Anion Exchange Membrane Fuel Cells
Authors: Shubair Asma , Gowling Alannah C. , Sundari Babu Varshini , Meek Kelly M.
Published: February 2025

Fuel cells offer a promising solution for clean energy conversion, with anion exchange membrane fuel cells (AEMFCs) being particularly attractive for their potential to use less expensive, non-platinum group metal (non-PGM) catalysts. Despite significant progress in AEMFCs in recent years, their performance is limited by instability often resulting from water imbalance within the cell (e.g, anode flooding, cathode dry-out). Implementing asymmetric electrode anion exchange ionomers (AEIs), i.e., using a hydrophobic AEI at the anode to inhibit swelling and a hydrophilic AEI at the cathode to prevent water depletion, could overcome issues of poor water management. In this study, block copolymer (BCP) AEIs of polydiallyldimethylammonium hydroxide-block-polystyrene (PDADMAOH-b-PS) were synthesized via reversible addition-fragmentation chain transfer polymerization, achieving ion exchange capacities of 1.03 to 3.40 mmol g−1. These BCP AEIs were employed in the AEMFCs to optimize water distribution by controlling the hydrophobicity/hydrophilicity of the gas diffusion layers. Our results demonstrated lower ohmic losses and mass transport limitations in the asymmetric electrode design vs the symmetric analog.
Adaptable Pectin Extraction and Functional Group Impact on Electrolytes Suitable for Energy Storage Applications
Authors: Wilson Nathan W. , Mete Bengu , Payne Nicholas J. , Tropp Joshua , Botte Gerardine G.
Published: February 2025

An alkaline de-esterification method was developed to modify the functional properties of pectin extracted from soybean hull waste. The process yielded pectin with degrees of esterification (DE) ranging from 40 to 0.40, which was then incorporated into symmetrical supercapacitors using carbon active material derived from in situ resource utilization (ISRU) methods for space exploration applications. Physical characterization via Fourier transform infrared spectroscopy, H1 nuclear magnetic resonance spectroscopy, and static light scattering revealed that precipitation pH significantly influenced DE, molecular weight, and yield. In electrochemical testing using coin cells with blocking electrodes, pectin with 27 DE demonstrated superior ionic conductivity of 17.51 S m−1, substantially higher than reported biopolymer alternatives. While initial supercapacitor cells using ISRU carbon showed modest capacity (∼1 F g−1) and specific energy (∼0.1–1 Wh kg−1), devices incorporating commercial carbon electrodes achieved markedly improved performance (2–5 Wh kg−1). The pectin-based hydrogel electrolytes exhibited promising characteristics including high specific power (1,000–11,000 W kg−1) and exceptional stability over 10,000 galvanostatic charge-discharge cycles with maintained coulombic efficiency, establishing their potential for future energy storage applications.
Integration of metabolomics and transcriptomics reveals the mechanism of TMEM30A downregulation induced FSGS podocyte injury
Authors: Hou Yanpei , Chen Sipei , Li Yi , Huang Liming , Zhang Huijian , Yu Min , Xiong Lin , Zhong Xiang , Wang Li , Zhu Xianjun , Li Guisen , Peng Lei
Published: February 2025

This study aimed to identify the key pathways and molecules of TMEM30A downregulation involved in FSGS podocyte injury. Through comprehensive transcriptomic and metabolomic analyses, as well as in vivo and in vitro experiments, we discovered that the downregulation of TMEM30A triggers podocyte injury by decreasing the levels of glycolysis-related molecules, including ALDOA, HK2, LDHA, and GAPDH, in FSGS.
Improving Container Port Efficiency: A Data‐Driven Model for Optimizing Truck Arrival Appointments Through Distributionally Robust Optimization
Authors: Sun Shichao , Dong Yao
Published: February 2025

The irregular arrival patterns of container trucks at ports have a substantial impact on logistics operations’ efficiency, resulting in congestion during peak hours and unused port capacity during idle times. Implementing a truck appointment system (TAS) is vital to address this issue effectively. This paper suggests enhancing the TAS by adopting a data‐driven approach using terminal gate data to understand the intricate and uncertain relationship between truck arrival patterns and port operational efficiency. Insights gained from these data are utilized to develop a distributionally robust optimization (DRO) model. This model provides an exact solution for optimizing the appointment quota plan of TASs, thereby improving port efficiency and addressing operational challenges. Compared to existing methods, this approach does not heavily rely on theoretical assumptions concerning the cooperation mechanisms among trucks, yard equipment, quayside equipment, and other facilities and fully considers the complex uncertainties in truck arrivals. Furthermore, to examine the effectiveness of the proposed model, a case study is conducted at Yan Port, China, aiming to achieve practical results. The numerical experiments comparing its performance with the conventional robust optimization (RO) model confirm the superiority of the proposed DRO model in minimizing the total truck turnaround time within the terminal and overall time expenses. This superiority stems from its integration of the respective advantages of stochastic optimization (SO) and traditional RO methods. By optimizing the appointment quota plan in this manner, it achieves a balanced distribution of truck arrivals, showcasing its significant potential to enhance port logistics efficiency.
A Robust Control Method for Reliability Improvement of Cascade H‐Bridge STATCOM Under DC‐Link Capacitance Uncertainty
Authors: Azimi Maede , Asadi Mehdi
Published: February 2025

This paper proposes a robust DC‐link voltage controller designed for a multilevel‐based static synchronous compensator (STATCOM), addressing both DC‐link capacitance degradation and load variations. The uncertainty in DC‐link capacitance is modeled as an external perturbation, leading to the development of a second‐order sliding mode controller (SOSMC) based on a twisting algorithm. This controller effectively manages these uncertainties, providing high stability and robustness against parameter variations and external disturbances. Furthermore, it reduces unwanted chattering and enhances overall system performance. The impact of DC‐link capacitance uncertainty on the reliability of multilevel converters is analyzed, comparing the proposed SOSMC with traditional proportional–integral (PI) controllers in the Simulink MATLAB environment. The results demonstrate that the SOSMC method outperforms the PI controller under 33% uncertainty in DC‐link capacitance over 5 years. The proposed control scheme not only meets reactive power demands but also effectively manages uncertainties in DC‐link capacitors. Additionally, the twisting algorithm maintains an acceptable total harmonic distortion (THD) index on the AC side, thereby improving overall reliability while reducing maintenance costs.
miR‐21‐5p Targets PIK3R1 to Regulate the NF‐κB Signaling Pathway, Inhibiting the Invasion and Progression of Prolactinoma
Authors: Li Min de , Yang Juan , Wu Xiao , Chen Shang Si
Published: February 2025

Prolactinomas (PRLs) are benign tumors with malignant characteristics that can invade the surrounding tissue structures and are challenging to treat. It has been reported that miR‐21‐5p expression in pituitary adenomas is correlated with tumor invasion and size. However, the mechanism of action of miR‐21‐5p in PRL remains unclear. Dysregulation of the phosphoinositide‐3‐kinase (PI3K) regulatory Subunit 1 pathway occurs frequently in cancer and plays an important role in tumor progression as an important component of the PI3K pathway. However, the role of PIK3R1 in PRL and its regulatory mechanism are unknown. In this study, we first explored the effect of miR‐21‐5p in PRL and then confirmed that PIK3R1 is a direct target of miR‐21‐5p using bioinformatics and cellular experiments. Subsequent in vitro experiments demonstrated that overexpression of PIK3R1 significantly attenuated the biological effects of miR‐21‐5p in PRL cells, such as promoting proliferation and invasion. Finally, we explored the mechanism by which PIK3R1 affects PRL progression and found that the inhibition of IκBa degradation by PIK3R1 impacts PRL progression via the miR‐21‐5p/PIK3R1/MMP pathway.
Drop‐Weight Impact Analysis of Unidirectional Sisal Fiber –Reinforced Epoxy Resin Composite Material for Automotive Application Based on ASTM D‐7136 Standard
Authors: Dagne Shiferaw Habtamu , Woldemariam Mulugeta H. , Tilahun Redda Daniel , Yimam Ahmed Amar
Published: February 2025

The main goal of this study is to investigate the drop‐weight impact analysis of sisal fiber–reinforced epoxy resin composite materials for automotive applications using Abaqus/CAE software based on the ASTM D‐7136 standard. For this simulation, a [0/0]s unidirectional sisal/epoxy composite laminate with an overall thickness of 2.16 mm was used, and 0.5, 1, 2, and 3 kg of a rigid hemispherical impactor mass with 1, 2, and 3 m/s of velocities were used to deal with their effects on the composite laminates. The result revealed that the initial damage mechanism in the impact event is the interplay matrix crack. After that, matrix and fiber debonding, fiber breakage, and penetration occurred depending on the mass and velocity of the impactor. In addition, when the impactor mass and velocity increase, the composite plate’s reaction forces and energy absorption increase up to 1 kg of the impactor at 3 m/s. However, for 2 and 3 kg of the impactor mass, the energy absorption capacity of the material is decreased due to the high damage and perforation of the composite laminate. In general, it is found that the unidirectional sisal fiber–reinforced epoxy resin composite material has a moderate energy absorption capacity in the transverse direction and has the potential to be used for different automotive interior body applications.
Datasets S1 from CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis
Authors: Zhang Qiangnu , Zhang Yusen , Fu Chuli , He Xiaoyan , Huang Zuotian , Wu Geyan , Wei Teng , Jin Wen , Yan Lesen , Wu Meilong , Peng Gongze , Fan LinLan , Li Mingyue , Guo Yuehua , Bi Jiangang , Bai Yu , Roessler Stephanie , Yan Guang-Rong , Liu Liping
Published: February 2025

Metabolomics data
Data from CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis
Authors: Zhang Qiangnu , Zhang Yusen , Fu Chuli , He Xiaoyan , Huang Zuotian , Wu Geyan , Wei Teng , Jin Wen , Yan Lesen , Wu Meilong , Peng Gongze , Fan LinLan , Li Mingyue , Guo Yuehua , Bi Jiangang , Bai Yu , Roessler Stephanie , Yan Guang-Rong , Liu Liping
Published: February 2025

Abstract
Cleavage stimulation factor subunit 2 (CSTF2) is a fundamental factor in the regulation of 3′-end cleavage and alternative polyadenylation of pre-mRNAs. Previous work has identified a tumor-promoting role of CSTF2, suggesting that it may represent a potential therapeutic target. In this study, we aimed to elucidate the mechanistic function of CSTF2 in hepatocellular carcinoma (HCC). CSTF2 upregulation was frequent in HCC, and elevated levels of CSTF2 correlated with poor patient prognosis. Although CSTF2 inhibition did not suppress HCC growth under nonstress conditions, it supported tolerance and survival of HCC cells under hypoxic conditions. Mechanistically, CSTF2 increased phosphoglycerate kinase 1 (PGK1) protein production to enhance glycolysis, thereby sustaining the energy supply under hypoxic conditions. CSTF2 shortened the 3′ untranslated region of PGK1 pre-mRNA by binding near the proximal polyadenylation site. This shortening led to a loss of N6-methyladenosine (m6A) modification sites that are bound by YTH m6A RNA-binding protein F2 and increase degradation of PGK1 mRNA. Concurrently, hypoxia increased m6A modification of PGK1 mRNA near the proximal polyadenylation site that was recognized by the YTH m6A RNA-binding protein C1, which recruited CSTF2 to enhance the shortening of the PGK1 3′ untranslated region. A small-molecule screen identified masitinib as an inhibitor of CSTF2. Masitinib counteracted PGK1 upregulation by CSTF2 and suppressed the growth of HCC xenograft and patient-derived organoid models. In conclusion, this study revealed a function of CSTF2 in supporting HCC survival under hypoxia conditions through m6A modification evasion and metabolic reprogramming, indicating that inhibiting CSTF2 may overcome hypoxia tolerance in HCC.

Significance: Targeting CSTF2 inhibits hepatocellular carcinoma survival in hypoxic microenvironments, which may be a promising therapeutic strategy for treating liver cancer.
Table 2 from Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence
Authors: McDonald Elizabeth S. , Pan Tien-Chi , Pant Dhruv K. , Troester Melissa A. , Kossenkov Andrew V. , Mankoff David A. , Mach Robert H. , Chodosh Lewis A.
Published: February 2025

PGRMC1 is weakly associated with TK1. PGRMC1 exhibits a significant correlation with TK1 when all cancers are combined, although the magnitude of these associations is weak. PGRMC1 vs. TK1
Appendicolith as a Sign of Complicated Appendicitis: A Myth or Reality? A Retrospective Study
Authors: Nikkolo Ceith , Muuli Mariliis , Kirsimägi Ülle , Lepner Urmas
Published: February 2025

Introduction: Appendicolith can be incidentally detected on abdominal computer tomography (CT) without any signs of appendicitis. However, it has also been found to be a risk factor for failure of nonoperative management in acute appendicitis. The present retrospective study aimed to evaluate whether appendicolith predicts complicated appendicitis in patients with any appendicitis. Methods: A retrospective chart review was conducted for patients undergoing appendectomy from January 2016 to December 2018. Appendicolith was considered to be present when it was described in a CT scan. Results: Of the 267 patients, appendicolith was found in 120 cases, while there were no in 147 cases in preoperative CT scans. In the case of complicated appendicitis (gangrenous or gangrenous perforated appendicitis), appendicolith was visible in CT scans in 57.7% of the patients. Of the patients with uncomplicated appendicitis, 38.3% had appendicolith in CT scan (p = 0.002). In univariate logistic regression analysis, based on the finding of the histological specimen, appendicolith was associated with complicated appendicitis (OR: 2.12; 95% CI: 1.28–3.51; p = 0.004). When adjusting for sex, age group (age ≤50 vs. >50 years), and duration of symptoms (≤24 vs. >24 h), the odds ratio was 3.52 (95% CI: 1.88–6.58; p < 0.001). Conclusion: Our study found that appendicolith can be considered an independent risk factor for complicated appendicitis. Therefore, in the presence of appendicolith, surgical treatment should probably be preferred over nonsurgical treatment in acute appendicitis.
Experiência do teleatendimento na reabilitação
Authors: Utiyama Daniela Mitiyo Odagiri , Andrade Viviane Caroline Sales de , Ayres Denise Vianna Machado , Alfieri Fábio Marcon , Battistella Linamara Rizzo
Published: February 2025

Objective: Report the experience of call center in patients with spinal cord injury, stroke and amputee in a rehabilitation center. It consists of three cases that started rehabilitation by call center in the rehabilitation center of the Institute of Physical Medicine and Rehabilitation of the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo (IMREA-HCFMUSP). This report shows that assessments such as the Functional Independence Measure (FIM), Timed Up and Go (TUG) test, 1-minute sit-and-stand test could be applied on platforms such as Dr. TIS®, Whatsapp®, before and after a physiotherapy program with the aimed at improving the functionality of these patients who, after the respective calls, could obtain improvements through call center. Conclusion: This rehabilitation model proved to be safe, beneficial and likely to provide remote care for these patients.
Avaliação da força de preensão palmar e limiar de tolerância a dor à pressão entre indivíduos jovens e idosos
Authors: Vitorino Cristiano Franco , Paislandim João Paulo , Fernandes Pedro Ferreira , Borges Rodrigo Santos , Oliveira Natalia Cristina de , Alfieri Fabio Marcon
Published: February 2025

Objective: Was to compare and verify the associations between muscle strength and pressure pain threshold (PPT) between elderly and young individuals. Methods: Observational cross-sectional study in which 53 volunteers participated and were evaluated in relation to muscle strength through handgrip strength tests, maximum isometric knee extension strength tests and trunk extension tests. The PPT assessment was carried out using algometry in the following regions: hand, vastus medialis, vastus lateralis, and lumbar region. Data were analyzed using the SPSS v.26 package and Spearman visualization coefficients were established. Results: The young group presented higher values in relation to dynamometry (p<0.05) in all assessments compared to the elderly, but no significant differences were found in relation to PPT. The group of young people showed significant and moderate associations (r= 0.410 to r= 0.599) between strength x PPT. In the elderly group, correlations ranged from moderate (r= 0.536 to r= 0.597) to strong (r= 0.607 to r= 0.725). Conclusion: Young people obtained higher values in strength assessments and in their relationship with the elderly, but there was no difference between the PPT between the groups. In the young group, moderate associations were found between the strength variables and PPT. In the elderly group, the associations between FPP x algometry were moderate and strong.
Efeitos do treinamento em esteira ergométrica sobre a funcionalidade na paralisia cerebral: uma revisão integrativa da literatura
Authors: Xavier Nathan Silva , Matias Larissa Hoehne , Matheus Denise , Castro Pedro Claudio Gonsales de , Battistella Linamara Rizzo , Imamura Marta
Published: February 2025

Objective: The aim of this integrative literature review was to analyze the key benefits of treadmill training (TT) for the functionality of ambulatory children and adolescents with cerebral palsy (CP). Method: Searches were conducted in the Pubmed, EMBASE, and Physiotherapy Evidence Database (PEDro) databases for studies published between 2013 and 2023. Results: Out of 428 studies found, 17 were selected for analysis and synthesis of knowledge. The studies demonstrated positive effects on ambulatory function, with changes in spatiotemporal and kinematic parameters of gait, as well as positive outcomes in gait capacity and performance measures. Additionally, significant changes were observed in gross motor function, mobility, and functional balance. TT protocols and methods varied among the studies, but most initiated training at lower walking speeds and durations, gradually increasing over the course of treatment, utilizing partial body weight support (PBWS) and manual facilitations depending on the severity of CP and gait function limitations. To enhance functionality, combining TT with other therapeutic modalities such as strength training and ground walking is recommended. Overall, the studies conducted TT two to three times per week, lasting six to twelve weeks. Conclusion: TT proved to be an effective and feasible therapeutic modality for application in the treatment of ambulatory children and adolescents with CP.
Efeito da terapia de fotobiomodulação na performance muscular de pacientes pós SARS-CoV
Authors: Quintanilha Naiane Ribeiro , Bilby Anne Sofia Pang , Pereira Franciele da Silva , Kuriki Heloyse Uliam , Marcolino Alexandre Márcio , Barbosa Rafael Inácio
Published: February 2025

Objective: To analyze the effects of photobiomodulation therapy PBMT on functional capacity and muscular performance in individuals after severe acute respiratory syndrome SARS. Methods: 15 individuals participated in the research, 7 from the active PBMT group (28.71 ± 12.91 years) and 8 individuals from the placebo PBMT group (28 ± 16.33 years) affected by COVID-19, randomly divided into two groups: placebo PBMT and active PBMT (E-Light IRL-DMC®, 288J). All volunteers underwent a final assessment using the Fatigue Assessment Scale (FAS), peak isometric strength (Lafayette Hand-Held Dynamometer™) of the knee extensors and the five-repetition sit-to-stand test (STS). Then, active or placebo PBMT was applied to six quadriceps sites of the dominant leg. Results: after the protocol the active PBMT for mean peak force obtained (34.31 ± 13.50) and the placebo PBMT group (31.11 ± 7.82) and in the TSLC5 active PBMT group 9.19 ± 1.75) and the placebo PBMT (9.18 ± 2.09), both with no significant difference in increased functional capacity and muscular performance between the groups. Conclusion: PBMT had no effect when compared to placebo in improving functional capacity and muscle performance in post- SARS individuals. Studies with greater sample size are suggested, with the aim of verifying the causal relationship between PBMT and the musculoskeletal repercussions after SARS.
Three Types of Existential Entailments in a Multi-domain Semantics
Authors: Rami Dolf , Köpping Jan
Published: February 2025

In this article, we argue for the distinction of three different types of predicates: existence entailing, (existence) neutral, and nonexistence entailing predicates. We provide linguistic tests as well as examples to motivate this distinction. After motivating our views on predicates, we show how our theory is able to deal with a multitude of problematic data both known from the literature as well as new. Then, we develop a multi-domain predicate logic inspired by certain versions of free logics in order to represent these entailments in a formal way.
Arrojadoa bahiensis subsp. minutiflora (Cactaceae, Cactoideae), a new subspecies from the Brazilian flora
Authors: GONZAGA DIEGO RAFAEL , PEREIRA FABRICIO DE OLIVEIRA
Published: February 2025

Arrojadoa bahiensis subsp. minutiflora is described on the basis of living collections and herbarium specimens. The new subspecies is considered endemic to the Brazilian Caatinga (Municipality of Piatã, Diamantina Plateau, Bahia State). Comments on its morphology in comparison with the similar taxa, as well as geographical distribution, phenology, habitat, conservation status, and original photographs are provided.
Gen Z Employees’ Adaptive Performance in Hybrid Workplaces: The Role of Inclusive Leadership, Creativity, and Work Engagement
Authors: Κatsaros Kleanthis K.
Published: February 2025

By drawing on the social exchange theory, the article suggests a moderated mediation model to examine the role of employee creativity and work engagement in the relationship between inclusive leadership and employee adaptive performance. Data were collected from 305 Gen Z employees in the Greek telecommunication industry and their supervisors in three sequential phases. The research findings suggest that employee creativity mediates the relationship between inclusive leadership and employee adaptive performance. Additionally, they provide support that work engagement moderates the relationship between employee creativity and adaptive performance, as well as, the indirect relationship between inclusive leadership and employee adaptive performance through employee creativity; such that the positive relationships are stronger when work engagement is higher. The results indicate that should leaders and change management practitioners manage to positively influence (Gen Z) employees’ creativity by employing inclusive strategies and procedures; they will boost their adaptive performance during change.
A Qualitative Study of Competencies of Coaches That Predict Client Behavior Change
Authors: Boyatzis Richard , Ehasz Sharon F. , Liu Han , Oosten Ellen Van
Published: February 2025

Coaching's rapid growth has increased pressure to have effective coaches. The competency models currently used for training and certification are based on opinion surveys. In management, such a process for developing competency models has been shown to confuse standards of excellence with prejudicial fads. This study examined competencies demonstrated in critical incident work samples of coaching by more effective and less effective coaches as measured by client behavioral change over 2 years. Effective coaches more frequently demonstrated the competencies of achievement orientation, empathy, emotional self-awareness, and coaching and mentoring as well as the total number of emotional and social intelligence competencies shown by a coach as compared to their less effective counterparts. More effective coaches discussed more role differentiation as a coach from other related roles as compared to less effective coaches. Implications for future research and practice in coach training and certification are discussed.
Adoption and abandonment of hybrid rice technology: The case of Bangladesh
Authors: Mottaleb Khondoker Abdul , Durand-Morat Alvaro , Fatah Fazleen Abdul , Sarkar Md. Abdur Rouf
Published: February 2025

Our study delves into the dual dynamics of adoption and abandonment of hybrid rice technology in Bangladesh, filling a gap in the literature that emphasizes technology adoption over abandonment. Drawing on primary data from 1301 farm households, the research empirically explores the factors influencing the adoption and abandonment of hybrid rice technology in Bangladesh. With rice being a staple in Bangladesh, the government seeks to boost hybrid rice adoption due to its higher yield potential. Descriptive findings highlight challenges, including inferior cooked rice quality and low market prices. Adoption is prominent among market-oriented farmers, while abandonment is associated with income earning from nonfarm sectors and self-consumption cultivation. Notably, Bangladesh imports over 75% of hybrid rice seeds, primarily from China and India, with less than a quarter developed domestically. The study recommends strategic investment in adaptive research to enhance hybrid rice grain quality specifically on amylose content in hybrid rice to make cooked hybrid rice less sticky. To achieve the objective, this study emphasizes collaborative efforts between national and international research organizations. It underscores the importance of developing and deploying hybrid rice technology with improved traits to cater consumer demand and to bolster food security. Additionally, the study advocates for strong financial support from international donor agencies to advance national adaptive research initiatives.
Non-destructive identification of cashmere and wool fibers based on PLS-DA and LDA using NIR spectroscopy
Authors: Chen Xin , Wang Fang , Zhu Yaolin
Published: February 2025

Manual identification of cashmere and wool fibers is often laborious, subjective, and time-consuming due to their extremely similar features. In order to non-destructively and accurately detect these animal fibers, this study proposes a novel detection method based on machine learning algorithms by near-infrared (NIR) spectroscopy. Building upon the preprocessing of NIR spectroscopy data of cashmere and wool fibers, both partial least-squares discriminant analysis (PLS-DA) and linear discriminant analysis (LDA) classifiers are used to distinguish cashmere and wool fibers. First, four data preprocessing methods are applied: mean normalization (MN), z-score standardization (ZSS), mahalanobis distance (MD), and discrete wavelet transform (DWT). Second, following the preprocessing, PLS-DA is used for feature extraction of the spectral data. Finally, based on the criterion of cumulative contribution rate of 80%, determine the number of principal components (PCs) and use the selected PCs as input for LDA. This study compares three feature extraction methods, principal component analysis (PCA), factor analysis, and sparse principal component analysis (SPCA), and two identification models, k-nearest neighbor (KNN) and decision tree (DT). Experimental results indicate that the proposed PLS-DA-LDA model outperforms the other 11 models, offering a new method for the identification of cashmere and wool fibers using NIR spectroscopy.
Intermittent hold control for exponential synchronization of fractional-order delayed complex networks with its application
Authors: Yao Xueqi , Shi Jingxi , Zhong Shouming , Du Yuanhua
Published: February 2025

The paper focuses on synchronization problems of a type of fractional-order complex systems with delays. First, a general exponential stability theorem is achieved by utilizing function of complex variable method and fractional-order calculus, which can handle a type of multiple delayed complex systems. Then, a novel intermittent-hold control is designed, which can reduce the information transmission by flexibly adjusting the control interval. Next, through the proposed theorem and controller, exponential synchronization results can be obtained by constructing simple Lyapunov functional. Meanwhile, the control gains can be calculated by linear matrix inequality. Finally, two simulations are given to show the effectiveness of the proposed results, and some comparisons with different control times and holding times verify the flexibility of control time selection.
Evidence for a Curvilinear Effect of Psychological Discomfort on Dominant Group Members’ Engagement in Allyship
Authors: Foster-Gimbel Olivia A. , Phillips L. Taylor
Published: February 2025

Psychological discomfort can motivate, demotivate, or even backfire upon efforts to encourage allyship. We consider the intensity of such discomfort to test curvilinear relationships between psychological discomfort and Whites’ engagement in equity efforts. Across four pre-registered studies ( N = 4,563), we find support for our curvilinear model. First, we explore the relationship between collective discomfort and allyship intentions. While we find that collective discomfort is linearly associated with greater allyship, we find little evidence of diminishing returns. Second, we find a curvilinear relationship between collective discomfort and defensive reactions: Both low and high discomfort was associated with increasing defensive reactions to evidence of racial inequity (victimhood claiming, stigma reversal) than moderate discomfort. Thus, we provide empirical support for the idea that dominant group members who experience high (vs. moderate) discomfort in the face of social inequality may be less likely to support equity. We offer insights on how to manage this issue
Unmasking Distress: An Analysis of COVID-19’s Mental Health Impact on Nurses in South Africa
Authors: Haine Phillipa , Kagee Ashraf , Coetzee Bronwyne , Janse Van Vuuren Marnus , Shongwe Lindokuhle
Published: February 2025

Background:

The acute mental health challenges faced by nurses during the COVID-19 pandemic have the potential to result in long-lasting psychological impacts. Promoting the mental health of nurses is crucial not only to safeguard their wellbeing but also to ensure the delivery of optimal patient care.

Objective:

This study sought to ascertain the extended mental health impact of the COVID-19 pandemic among nurses in South Africa.

Methods:

Participants involved nurses working at four hospitals in the Western Cape province: Helderberg, TC Newman, Stellenbosch, and Tygerberg. A convenience sample of nurses ( N = 264) from the four hospitals participated in the study. Data collection involved an online survey, which included a comprehensive battery of psychological measures, such as fear of COVID-19, perceived vulnerability to disease, anxiety, depression, post-traumatic stress disorder (PTSD), alcohol use, and worry about COVID-19 infection.

Results:

The mean age of participants was 34.4 ( SD = 7.9), with a majority being female (82%). Age was positively correlated with hopelessness and life satisfaction but negatively associated with fear of COVID-19 and symptoms of anxiety, PTSD, alcohol use, and depression. Nurses in the private sector reported higher levels of alcohol use and PTSD than nurses in public, while married and partnered nurses reported reduced levels of anxiety compared to their unmarried counterparts. Higher education levels were associated with reduced adverse mental health outcomes.

Conclusion:

Psychological distress among nurses was exacerbated even after the peak of the COVID-19 pandemic. Potential areas of concern are highlighted, indicating the need for targeted interventions.
Day-ahead and Reserve Prices in a Renewable-based Power System: Adapting Electricity-market Design for Energy Storage
Authors: Deman Laureen , Siddiqui Afzal S. , Clastres Cédric , Boucher Quentin
Published: February 2025

Decarbonizing the power mix will require investments in storage and flexibility options to replace the current carbon-intensive supply of reserves. This paper questions whether reserve-capacity markets can serve as a capacity mechanism for flexible technologies. A fundamental model of the day-ahead and reserve markets is used to investigate the evolution of reserve prices with large shares of renewable energy and storage. The model represents the current market design in Continental Europe with a centralized supply and platforms for the exchange of reserves. By becoming the main suppliers of reserve capacity, batteries have a noticeable impact on reserve prices. Their flexibility implies zero opportunity cost most of the time, meaning that the flexibility is not rewarded by the market. These results suggest that reserve-capacity markets cannot provide additional remuneration for flexible technologies and, thus, do not solve the missing-money problem in the context of the energy transition.

JEL Classification: Q41, Q47