bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of lung consolidation with clinical prognosis in children with Mycoplasma pneumoniae pneumonia: a retrospective study
Authors: Chu Caiting , Wang Lijun , Li Huajun , Xu Shanshan , Zhang Liya , Liu Quanhua , Zhang Xi , Zhang Weixi , Li Wenhua , Huang Lisu
Published: May 2021

Objectives

Lung consolidation is common in patients with Mycoplasma pneumoniae pneumonia (MPP). In this study, we aimed to investigate whether this lung lesion associated with the severity and prognosis of MPP.
Methods

Clinical experts reassessed and collected the clinical characteristics, imaging features, and laboratory examination of 752 hospitalized children with MPP who received low-dose computerized tomography (CT) examination between August 2014 and July 2019. We evaluated the impact of lobar consolidation on the fever duration and length of hospital stay using Kaplan-Meier analysis and COX model. The relationship between lobar consolidation and inflammatory markers was also determined, as well as hospital charges.
Results

Among the 752 patients included, 90.3% (679/752) presented lung consolidation, 25.1% (189/752) with 2 or more lobar consolidation, and 16.2% (122/752) patients developed severe MPP (SMPP). Beyond pleural effusion, lobar consolidation had the highest risk of SMPP among low-dose CT imaging-based evidence. Compared with 0 and 1 lobar consolidation, 2 lobes, 3 lobes, and 4 lobes were associated with a 1-fold, 3.1-fold, and 7.5-fold increased risk of SMPP (OR 2.0 [95% CI 1.3–3.2], OR 4.1 [95% CI 2.0–8.5], OR 8.5 [95% CI 2.2–32.6]). The length of stay and fever duration were prolonged correspondingly with increase of number of lobar consolidation, as were hospital charges.
Conclusion

Lobar consolidation is a stable and reliable CT feature for assessing of severity of illness and clinical prognosis for children with MPP.
COVID-19 Data Published by Turkey is Fake or Not?
Authors: Guliyev Hasraddin
Published: May 2021

Turkey attempt to control the fast-rising number of coronavirus cases and deaths since the spread of coronavirus disease 2019 (COVID-19) in every country. Likewise, researchers from different fields have been an effort to explore COVID-19 with distinctive aspects for minimizing the cost of a pandemic on the economy and social life. We know that is impossible reliable and unbiased results of studies without accurate data. Thus, if we gather inadequate data and analysis it, we will be faulty decisions and make policies. For this reason, Benford's Law may be useful for assessing the effects of the current control interventions and may be able to answer the question, ‘‘How flat is flat enough?’’. In this study, we explore whether the COVID-19 data published by Turkey is fake or not with Benford's Law.
DLG2 impairs dsDNA break repair and maintains genome integrity in neuroblastoma
Authors: Keane Simon , de Weerd Hendrik A. , Ejeskär Katarina
Published: May 2021

Background: In primary neuroblastoma, deletions on chromosome 11q are known to result in an increase in the total number of chromosomal breaks. Microhomology mediated-end joining (MMEJ) is an error-prone pathway for DNA double-strand break repair that is often upregulated in cancer. DLG2, a candidate tumor suppressor gene on chromosome 11q, has previously been implicated in DNA repair.Methods: We evaluated an association between MMEJ gene expression and neuroblastoma patient outcome, risk categorization, and 11q status using publicly available microarray data from independent neuroblastoma patient datasets. Functional studies were conducted using comet assay and H2AX phosphorylation in neuroblastoma cell lines and in the fruit fly with UVC-induced DNA breaks. Results: We show that the MMEJ genes PARP1 and FEN1 are over expressed in neuroblastoma and restoration of DLG2 impairs their gene and protein expression. When exposed to UVC radiation, cells with DLG2 over expression show less DNA fragmentation and induce apoptosis in a p53 S46 dependent manner. We could also confirm that DLG2 expression results in CHK1 phosphorylation consistent with previous reports of G2/M maintenance. Conclusions: Taken together, we show that DLG2 expression increases p53 mediated apoptosis in response to genotoxicity, by maintaining S317 CHK1 phosphorylation and reducing the DNA replication machinery.
Die Väterbeteiligung in Europa und der Schweiz — Die Rolle der Väter für mehr Gleichberechtigung
Authors: Lütz Fabian
Published: May 2021

Nachdem die Europäische Union (EU) mit der Verabschiedung der Work-Life Balance Richtlinie (WLB-RL) zum ersten Mal im EU-Recht einen zehntägigen Vaterschaftsurlaub verankert hat und die Schweiz am 27. September 2020 im Rahmen der Volksabstimmung ebenfalls einen zehntägigen Vaterschaftsurlaub angenommen hat, lohnt sich ein Blick auf beide Rechtssysteme, um Gemeinsamkeiten und Unterschiede herauszuarbeiten. Der vorliegende Beitrag verfolgt einen rechtlichen und verhaltensökonomischen Ansatz und analysiert das europäische und schweizerische Recht vor dem Hintergrund des Zielsder Gleichstellung von Männern und Frauen. Schliesslich wagt er einen Ausblick und arbeitet rechtsvergleichend Reformmöglichkeiten heraus, die sich jeweils aus dem europäischen und Schweizer Recht für das jeweils andere Rechtssystem ergeben.

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Suite à l’inscription d’un congé de paternité de dix jours dans le droit de l’Union européenne, par l’adoption de la directive concernant l’équilibre entre vie professionnelle et vie privée (dite « Work-Life Balance »), et dans le droit suisse à l’issue du référendum du 27 septembre 2020, une analyse des similitudes et différences entre ces deux systèmes juridiques s’avère judicieuse. Cette contribution adopte une approche juridique et comportementale qui analyse les droits européen et suisse dans le contexte de l’objectif de l’égalité entre les hommes et les femmes. Enfin, il ouvre une perspective et suggère, sur la base de cette approche comparative, des possibilités de réforme, respectivement pour les systèmes européen et suisse.
Avaliação dos hábitos de higiene bucal de usuários de prótese dentária removível
Authors: Alencar Andressa Aires , Rodrigues Parente César Augusto , Dantas Eldon Saraiva , Lima Heron Teixeira , Silva Cosmo Helder Ferreira da
Published: May 2021

A reabilitação bucal tem por objetivo substituir dentes e tecidos bucais ausentes, bem como melhorar a função do sistema estomatognático e promover uma estética satisfatória. No entanto, o uso de um aparelho protético pode aumentar a predisposição à cárie, ocasionar alterações no periodonto e processos inflamatórios na mucosa. Este estudo verificar os hábitos de higienização das próteses e da cavidade bucal de dos usuários de próteses removíveis atendidos em uma Unidade Básica de Saúde do município de Iguatu-CE. Foi aplicado um questionário que continha perguntas relacionadas aos dados socioeconômicos, utilização dos métodos químico e mecânico de escovação das próteses e da cavidade oral, uso de soluções desinfetantes, hábito de dormir com a prótese e orientações recebidas pelo profissional. Os dados foram avaliados através de análise descritiva. A pesquisa envolveu 35 indivíduos portadores de próteses totais ou parciais removíveis, sendo 74,28% (n=26) mulheres, com média de idade de 60 anos e renda familiar mensal de até um salário mínimo. Os participantes relataram utilizar as mesmas próteses há mais de cinco anos e não terem recebido orientação profissional quanto à higienização oral. Além disso, 62,86% (n=22) dormem com as próteses em boca, 74,29% (n=26) declararam escovar até 3 vezes ao dia e o método da escova e creme dental foi o mais utilizado. O nível de conhecimento sobre o uso, conservação e higienização de próteses totais da população estudada precisa ser melhorado, uma vez parte da população ainda apresenta hábitos inadequados.
Evaluating the Business and Owner Characteristics Influencing the Adoption of Online Advertising Strategies in the U.S. Green Industry
Authors: Torres Ariana P. , Rihn Alicia L. , Barton Susan S. , Behe Bridget K. , Khachatryan Hayk
Published: May 2021

Online advertising is becoming a mainstay business practice to reach firms’ customer bases. Yet, the adoption and use of online advertising in the green industry are topics that have not been adequately researched. Using a national survey of green industry firms conducted in 2019, this research uses a double-hurdle model to investigate factors that impact firms’ adoption of, and amount spent on, online advertising. Our results show that one-third of the companies invested in online advertising. Of those investing in online advertising, the average percentage of online advertising as a share of all advertising expenditures was 46%. Small businesses were less likely to invest in online advertising compared with larger businesses; however, once they invested in online advertising, the percentage of investment was 25% higher among small firms when compared with their larger counterparts. Increasing years in operation as well as trade show participation was related to a 3% decrease in likelihood to use online advertising. Business owners who perceived hiring competent employees as a barrier to business growth invested 19% less of their advertising budget in online channels, which may indicate a lack of human resources to advertise online. We also compared the industry results with data from a 2014 survey and found the amount invested in online advertising increased ≈3% to 5% between studies. The percentage in wholesale sales influenced the amount spent on online advertising in 2014 but not in 2019. Being a small firm in 2014 increased the amount spent on online advertising, but the effect was 14% lower in 2019. In 2014, firms located in the Pacific, Southcentral, and Southeast U.S. regions invested more in online advertising compared with other regions, but in 2019, the only geographic difference was that firms in the Great Plains spent less on online advertising. Despite their lower adoption rates, the increased expenditures on online advertising implies that smaller firms that implement online advertising receive value through that channel and are willing to allocate more resources to leverage its reach. Firms contemplating adopting and investing in online advertising should consider their resource availability and marketing goals related to reaching different customer groups through online advertising.
Results of using 3-D simulation methods in treatment of midfacial fractures
Authors: Khudyk Anton , Grigorov Sergey
Published: May 2021

The article publishes the results of treatment of 27 patients with fractures of the face middle area, of which 14 used standard titanium mini-plates to reposition the fragments, and 13 – individual 3D simulated titanium mini-plates / grids. Before and after treatment, its effectiveness was assessed by the values of the displacements of bone fragments and the index of the visual-analog scale, which allows determining the functional and cosmetic effect of the surgery. It was found that the use of individual 3D simulated titanium mini-plates / grids allowed obtaining in 85 % of patients displacements not exceeding 3 mm. In 72 % of patients in whom standard titanium mini-plates were used, the displacement after surgery was 3.1–6 mm, which is significantly greater than in the group with individual modeling of structures.

On the 7th day after surgery in the first group (treatment with standard mini-plates), the index on the visual-analog scale was 11 (7; 13), which was significantly (p=0.00147) less than before surgery. In the second group (treatment using individual 3D simulated titanium mini-plates / grids) the index on the visual analog scale was 4 (6; 8) points, which was significantly (Z=3.3; p=0.00098) less than before surgery. Comparison of the visual-analog scale of the first and second groups on the 7th day after surgery revealed the presence of significant (U=2.47; p=0.013) differences. The obtained results testify to the greater efficiency of individual 3D modeled titanium mini-plates / grids in comparison with standard titanium mini-plates.

The object of the research: fractures of the middle area of the face. Comparison of the visual-analog scale of the first and second groups on the 7th day after surgery revealed the presence of significant (U=2.47; p=0.013) differences.

Investigated problem: the comparative evaluation of the effectiveness of the middle area of the face fractures treatment using individual 3D simulated titanium mini-plates / grids and standard titanium mini-plates.

The main scientific results: Optimizing the treatment of fractures of the face middle area will help to achieve good cosmetic and functional results.

The area of practical use of the research results: Department of Surgical Dentistry and Maxillofacial Surgery.

Innovative technological product: The proposed technique using individual 3D-simulated titanium miniplates will help to optimize the treatment of patients with traumatic fractures of the face middle area.

Scope of the innovative technological product: Clinical practice.
Method of evaluation of the minimal sample size for acoustical signal therapy monitored via electroencephalographic activity of human brain
Authors: Pareniuk Dmytro
Published: May 2021

The aim of the study. Improvement of the preparation to the acoustical signal therapy test or experiment of electroencephalographic activity of human brain and validation of the specified test results.

The problem to be solved. Estimation of the minimal possible sample size for maintaining needed research accuracy in the research field of the electroencephalographic activity of human brain via monitoring of the brainwave patterns during exposure to the musical signal.

Main scientific results. New method for selection minimal passable sample size for brainwave pattern studies is presented. Example of application of method for one rhythm of the brainwaves (delta-rhythm) is shown. Perspective way of obtaining clinically valuable differences between test group results was acquired. Differences between mean values for groups of results of different types of music and stress factor exposure are presented.

The area of practical use of the research results. Research facilities dedicated to the study of electroencephalographic activity of human brain and medical facilities and institutions, dedicated to the treatment of pathologies of the central nervous system, brain damage, stress, and progressive post-stress action psychological state restoration.

An innovative technological product. Dedicated method for quick estimation of minimal passable sample size for brainwave pattern studies, which is recommended for usage in the studies of the implementation of music therapy.

The area of application of an innovative technological product. Electroencephalographic activity of human brain study via brainwave pattern research. Clinical practice of application of a music therapy.
Comparison of distance education problems during the COVID-19 pandemic
Authors: Klochko Vitalii , Kulynych Tetiana , Chuiko Natalia , Postolna Natalia , Holovanova Olena
Published: May 2021

The object of research: distance learning in higher educational institutions of Ukraine and the world during the COVID-19 pandemic.

Investigated problem: building a higher education system during the COVID-19 pandemic, capable of quickly adapting to adverse conditions and providing a high level of training.

The main scientific results: explored trends regarding the study of the impact of the pandemic on higher education, the effectiveness of distance education. Analyzed Ukrainian studies of distance education in universities. Held by students of the KNTEU Kharkiv Trade and Economic College. Based on the research results, conclusions and recommendations were made regarding the improvement of the quality of distance education in the field of higher education.

The area of practical use of the research results: higher education and professional education organizations.

Technological innovation: identified the problems of distance education during the COVID-19 pandemic, based on them, recommendations were developed to improve the quality of education in higher educational institutions of Ukraine.

Scope of application for technological innovation: practical activity in higher education and relations with stakeholders of educational organizations.
Development of main principles and tasks of Jewish national movement for revival of the state by Vladimir Zhabotinsky
Authors: Radchenko Liudmyla
Published: May 2021

The social and political activity of V. Zhabotinsky as a Jewish politician, a famous Zionist, the founder of modern Israel and a multifaceted personality. Its focus on the consolidation of Jewish political and social organizations, the development of a common platform on the basic principles and objectives of the Jewish national movement for the revival of statehood and the involvement of Jews from around the world in this process is substantiated. V. Zhabotinsky's commitment to the Ukrainian national movement is proved.

The object of research: V. Zhabotinsky as a great political figure of the Jewish and Ukrainian national movement.

Investigated problem: V. Zhabotinsky contribution to the consolidation of Jewish political and public organizations, to the development of Zionist theory, the basic principles and tasks of the Jewish national movement for the revival of the independent Jewish state of Israel and the solution of the Ukrainian national question.

The main scientific results: based on the analysis of socio-political activities and creative achievements of V. Zhabotinsky as a Jewish politician, his focus on defining a common platform on the basic principles and tasks of the Jewish national movement for the revival of statehood, involving Jews from around the world. V. Zhabotinsky's commitment to the Ukrainian national movement was revealed.

The area of practical use of the research results: determined by the suitability for practical use of modern Jewish political and public organizations to preserve Jewish national identity, ideology and organization of the revisionist movement, as well as to address the Ukrainian issue of bilateral relations, understanding nationalism as a great life idea has nothing to do with chauvinism, racism or any form of ethical supremacy.

The results can be used in the development and teaching of courses: "World History" and "History of Ukraine".

Innovative technological product: on the basis of numerous sources and materials, some of which are introduced into scientific circulation for the first time, the V. Zhabotinsky Institute (Tel Aviv) has filled a significant gap in V. Zhabotinsky 's contribution as a great figure of the Jewish national movement. His commitment to the Ukrainian national movement is substantiated, the myth of eternal antagonism between Jews and Ukrainians is refuted, arguing that the two people have lived on Ukrainian lands for thousands of years.

Scope of the innovative technological product: theoretical research, development of Zionist theory and practice of preserving Jewish national identity, ideology and organization of the revisionist movement, solution of the Ukrainian national question.
Kharkiv organization of the CP (b) U: a study of the formation of totalitarian principles of internal party life (1920-1929)
Authors: Redka Sergiy , Yaremchuk Nadiia , Prykhodko Tetiana , Zolotoverkha Viktoriia , Borzilo Lesia
Published: May 2021

The object of research: Kharkiv organization of the CP (b) U as a component of the institutions of the political system of Ukraine.

Investigated problem : The article depicts the process of transformation of the party organization of the Communist Party of the Bolsheviks of Ukraine of the Kharkiv province into a totalitarian organization.

Main scientific results: From the very beginning, Communist Party of the Bolsheviks of Ukraine of the Kharkiv province was created as an undemocratic organization. But in the early 1920s, the internal party life of the party organization was characterized by some features of democracy. After the civil war, some communists demanded greater freedom of criticism, the initiative of the masses, and the fight against bureaucracy, but the opposition in the party organization, in contrast to the all-Union center, did not have an ideological platform. They were dissatisfied with the low financial status of ordinary communists and the privileges of the party nomenclature. The party apparatus resisted attempts to democratize party life, and ordinary communists were unable to resist this process. As a result, the party organization of Kharkiv region was transformed into a totalitarian organization, which was characterized by unanimity, intolerance of criticism, strict centralization, lack of election, powerlessness of ordinary members and uncontrolled power of the party apparatus.

Field of practical usage of research results: determined by suitability for use in the field of the modern state formation by politicians, parties, public organizations, state institutions, and the media.

Innovative technological product: on the basis of numerous archival materials, many of which are introduced into scientific circulation for the first time, a significant gap has been filled in the ideas about the process formation of totalitarian principles of internal party life at the regional level, namely in Kharkiv region.

Field of application of innovative technological product: the practice of forming, implementing and improving the system of state regulation by politic parties.
Biochemical composition of vegetable raw materials and the impact of dosage on the properties of processed cheese
Authors: Tlevlessova Dinara , Alimardanova Mariam , Kazhymurat Assemay
Published: May 2021

The object of research is the cream cheese, elaborated using vegetable raw materials.

Investigated problem: This article provides information on the biochemical composition of leaves of A. odorum. The leaves of wild onions revealed a high content of vitamin C, macro- and microelements and other biologically active substances, indicating high nutritional and vitamin value and prospects of these species for use as fillers in the dairy industry.

The main scientific results: A. odorum refers to green vegetable plants, rich enough variety of biologically active substances. Unlike other perennial species of onion, A. odorum characterized by low protein content (1.1–1.8 %) and a relatively high solids content (in the bulb up to 17 % in the leaves 10,5–11,3 %), sugars (10,9–12,1 %).

The area of practical use of the research results: There will be researched a possibility of Allium odorum usage as an addition for new processed cheese production and an influence of plant raw material dosage on structure of the processed cheese.

Innovative technological product: Products developed within the framework of integrated technology are distinguished by high quality, nutritional value, safety, preservation of special nutrients: essential amino acids, fatty acids, omega 6 vitamins, bioflavonoids. The recipe solutions about the elements of innovative complex technologies are reflected in the patents that are included in the Derwent database.

Scope of the innovative technological product: Plant raw materials can be used both in pharmaceuticals to isolate saponins and to increase the nutritional and biological value of food products. In this article, we considered it in the production of processed cheeses, but it can be used as a seasoning for dishes. Content of inulin, quercetin, saponins, vitamin K, selenium, etc. makes this source very promising, it also has fungicidal properties and allows you to increase the shelf life of food products.
Social and economic efficiency of implementation of pastile products made from unconventional raw materials in the hospitality field
Authors: Sokolovska Olena , Radchenko Anna , Biletska Yana , Krivtsova Anna , Kornitskaya Anastasia , Afanasieva Tetyana , Bilovska Olha
Published: May 2021

In the context of the deteriorating environmental situation, scientists are faced with the urgent task of improving the quality of food. One way is to reduce the carbohydrate load by replacing sugar in sweeteners while enriching them with nutrients. One way is to reduce the carbohydrate load by replacing sugar in sweeteners while enriching them with nutrients. For this purpose, a number of studies have been carried out to improve the quality of pastilles through the use of stevia - a natural sweetener and elamin

The objects of research are social and economic efficiency.

Investigated problem was to calculate the social and economic efficiency from the introduction of the developed marshmallow.

Main scientific results: The article presents these calculations of the economic efficiency of the implementation of the development, namely, a decrease in the realizable value of the Exotica pastille by 1.2 % and an increase in the "Smakota" pastille and "Nasoloda" marshmallow by 4.0 and 2.3 %. However, it was found that the integral quality indicator of marshmallow "Nasoloda" exceeds the control by 10.2 %, for the pastille "Exotica" and "Smakota" – by 21.1 and 26.3 %.

Scope of practical use of the development is the food industry, namely, the expansion of the range of products with a low glycemic index, increased nutritional value.

An innovative technological product is the technology of making pastilles, which has economic and social efficiency.

Scope of application of the innovative technological product: The use of the developed pastille products for consumers with a lack of iodine, selenium, iron, obesity patients and diabetes mellitus.
Development of extreme regulator of separation moisture from the gas stream
Authors: Kulіnchenko Heorhіi , Leontiev Petro , Drozdenko Oleksii
Published: May 2021

Object of study: Automation of control of technological parameters of the process of low-temperature separation (LTS) of moisture from a gas stream.

Investigated problem: Improving the efficiency of the separation process when preparing gas for transportation through the consumption network. Development of hardware and software tools that provide automation of the process of regulating flow parameters under conditions of action of time-varying disturbances.

Main scientific results: A criterion for controlling the LTS process of a gas flow is formulated. The difference in the dynamic characteristics of the processes occurring during the separation of moisture makes it possible to effectively use a two-circuit control system. The perspective of using extreme regulators (ER) of the process, which is characterized by time delays between the input of the object and its output, is substantiated. The use of ER ensures the stability of the control process under the influence of disturbances in the parameters of the gas flow.

In the MATLAB environment, an ER model has been developed, in which a step-type algorithm is used, which provides an increase in the efficiency of the LTS process in accordance with the selected criterion

The area of practical use of research results: The scope of use of the research results are automation objects that need continuous automatic tracking of the changing settings of the process parameters regulators. The studies carried out make it possible to use the proposed regulator in various technological installations for drying gas and air (with appropriate identification of the parameters of the object).

Innovative technological product: Based on the formed criterion for controlling the LTS process, which is aimed at increasing the efficiency of the LTS process of moisture from a gas flow, a microprocessor-based step-type ER has been developed. Preliminary tests of the regulator show that it can be implemented on commercially available program logic controllers on the market.

Scope of application of an innovative technological product: The considered ER can be used to construct control systems for oil and gas transportation processes, which require adaptation and optimization modes to flow parameters. In this case, the need for adaptation is dictated by changes in flow parameters over time.
Antibacterial Activities of Methanolic Extracts of Different Seaweeds from Iskenderun Bay, Turkey
Authors: AYDIN Betül
Published: May 2021

Antibacterial activities of the methanolic extracts of Stypopodium schimperi (Kützing) Verlaque and Boudouresque, Halopteris filicina (Grateloup) Kützing, Dictyota dichotoma (Hudson) J.V.Lamouroux, Gracilaria bursa-pastoris (S.G.Gmelin) P.C.Silva, Ulva intestinalis Linnaeus species from the Iskenderun Bay, Turkey against Escherichia coli, Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhimurium and Proteus vulgaris were evaluated by using the microdilution method. Results of the study showed that all of the extracts had an antimicrobial effect on the tested bacteria. A minimum inhibitor concentration and minimum bactericidal concentrations of the extracts ranged from >125 to <0.39 mg mL-1. Furthermore, this is the first report on antibacterial effects of the methanolic extracts of S. schimperi (Kützing) Verlaque and Boudouresque and G. bursa-pastoris (S.G.Gmelin) P.C.Silva species. The present findings revealed that all studied seaweed species could act as a natural source of bioactive compounds for the treatment of infectious diseases.
Membangun Nisbah Kehidupan Rumah Tangga: Tafsir Kolose 3:18-4:1
Authors: Panjaitan Firman
Published: May 2021

Abstract Household codes are often characterized by a patriarchal pattern that allows hierarchical relations between husband-wife and parent-child, including in terms of work. The hierarchy creates a condition of ordinationsubordination, which suggests that there are strong and weak parties. This resulted in the idea that the strong owns the weak. Colossians 3:18-4:1criticizes the household rules constructed according to the philosophical views that developed at that time. Using historical-criticism methods, especially textual criticism, namely studies that specialize in research on text or words, this article suggests that the phrase “in God” is a reference for a household code based on an equality principle. This research also reveals that the relationships constructed in Colossians 3:18-4:1 negatethe hierarchical model.

Abstrak Aturan kerumahtanggaan sering kali diwarnai dengan pola patriarkhi yang mengizinkan adanya hierarki dalam nisbah antara suami-istri dan orang tua-anak, termasuk juga dalam hal bekerja. Hierarki menimbulkan kondisi ordinasi-subordinasi, yang mengesankan ada pihak yang kuat dan lemah, dan dampak yang terjadi adalah munculnya status kepemilikandari yang kuat terhadap yang lemah. Kolose 3:18-4:1 hendak mengkritik aturan kerumahtanggaan yang telah terbangun selama ini akibat pengaruh pandangan filsafati yang berkembang pada saat itu. Dengan menggunakan metode historis-kritis,khususnya kritik teks, yaitu studi yang mengkhususkan pada penelitian terhadap teks atau kata, artikel ini hendak memperlihatkan bahwa aturan kerumahtanggaan dan kerja yang dibangun harus didasarkan pada ekualitas/kesejajaran, dan kata kunci dalam membangun kesejajaran itu adalah frasa “di dalam Tuhan”. Penelitian ini menghasilkan sebuah temuan yang menunjukkan bahwa nisbah yang dibangun dalam Kolose 3:18-4:1 mengenai aturan kerumahtanggaan dan kerja “di dalam Tuhan” adalah nisbah yang menafikan hierarki.
Translation Shifts on Reference by Machine Translation in Descriptive Text
Authors: Sipayung Kammer Tuahman
Published: May 2021

Translation shifts are one of strategy to get a high-quality translation. It’s also used to solve the absent meaning on the target text. The objectives of this research are to describe the translation shifts (based on the theory of Blum-Kulka about kinds of shift and Halliday and Matthiesen on cohesion theory), which are done by machine translation in descriptive texts. The researcher used a descriptive qualitative research design to achieve the aims of this research. The source of data in this research is descriptive text. The data of this research are pair of words in source and target text. The form of words (pair of words in source and target) are in reference form based on the theory of Halliday about lexical devices. The researcher used interactive data analysis (data condensation, data display, and verifying/conclusion) to get the research findings. This research shows that Yandex translation made translation shifts more (35 times) often than the others. From the whole types of translation shifts (cohesion shifts: implicitation, explicitation, and meaning change), implicitation shift placed a high frequency among machines translation, however explicitation shift placed in the low frequency, and the medium frequency is placed by meaning change. It is to indicate that machine translation still lacks to produce a high level in the target than a source.
How do Nigerian Gynaecologist in a Tertiary Health Facility Manage Infertile Patients for Sexual Dysfunction?
Authors: O Orji Ernest
Published: May 2021

This study was conducted to evaluate the approaches gynaecologists in Osun East Senatorial district; South west Nigeria uses to screen and manage their infertile women for sexual dysfunction. Forty gynaecologists and their resident doctors managing infertile women at Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria, were interviewed (June -December 2020) using an in-depth-interview guide and semi-structured questionnaires. All the forty doctors assessed the sexual functioning of infertile patients. The Assessment was usually done at the first time of seeing the patient and at other times when patients start a discussion about it or when a patient’s complaints are directly related to it. Ways of eliciting sexual concerns were by asking on the frequency of sexual intercourse per week, about ejaculatory intercourse, sexual satisfaction, and dyspareunia. None of them used any standardized assessment tools to screen infertile women. Most are not aware of any standardized tools for sexual functions assessment because they had no training in sexual dysfunction in both undergraduate and postgraduate training as it was not in their curricula. While they welcome the introduction of the tools in training and in the case file of patients, they believed that routine screening using these tools would increase the waiting time and would be an added burden on the doctors. This study showed that gynaecologists and residents are poorly equipped to address sexual problems and sexual dysfunction among infertile women. It is imperative that the curricula of medical training be updated to include assessing sexual functioning tools for better care.
A case of intoxication with tea made from Digitalis purpurea
Authors: Lehmann Anouk , Späni Selina , Harings-Kaim Annette , Probst Cecilia , Christ Andreas , Leuppi-Taegtmeyer Anne B
Published: May 2021

We present the case of a 34-year-old woman with recurrent depressive disorder who ingested purple foxglove with suicidal intent. She bought a foxglove plant (Digitalis purpurea) over the internet and used all of its leaves to make a tea that she then drank over a period of a few hours. Seventeen hours later, she developed abdominal pain, emesis and bradycardia and was admitted via the emergency department to the intensive care unit for further treatment and monitoring. The plasma digoxin concentration measured 3.53 nmol/l (therapeutic reference range 0.77-1.50 nmol/l) 21 hours after ingestion of the tea. She remained heamodynamically and neurologically stable, was treated with antiemetics and simple analgesia and did not require digoxin-specific antibodies. Despite normal renal function, her plasma digoxin half-life was prolonged (estimated 76 h), reflecting the long half-life of the parent compound digitoxin which is the main cardiac glycoside in Digitalis purpurea. She was transferred to psychiatric care 48 h after admission. In this report, we compare this case to other similar cases, which to date have only been rarely reported in the literature.
Could heart rate recovery and exercise capacity predict abnormal 99mTc-MIBI myocardial perfusion scan findings?
Authors: Naghedi Aryan , Namiranian Nasim , Goudarzi Mohsen , Moghadam Reza Nafisi , Razavi-Ratki Seid Kazem
Published: May 2021

Background and aim: Ischemic heart diseases lead to numerous deaths worldwide. Prevention, rapid diagnosis and treatment are principal strategies in controlling mortality due to coronary artery diseases (CAD). Considering variety of options, finding suitable diagnostic modality for each patient has been controversial for long times. Exercise treadmill test (ETT) is a well-known and old modality compared to radionuclide scintigraphy. In this study we aimed to assess if heart rate recovery (HRR) and exercise capacity (EC) in ETT can predict perfusion defects in 99mTc-MIBI SPECT myocardial perfusion imaging (MPI).Materials and methods: In this cross-sectional, descriptive-analytic study, we enrolled 254 patients referred for MPI to nuclear medicine department of Afshar or Shahid Sadoughi Hospital, Yazd, Iran. All patients underwent ETT and MPI. HRR and EC in ETT plus abnormal perfusion findings in MPI along with patient’s history and demographic information were recorded in a questionnaire. Finally, all data were analyzed using SPSS ver.22 software.Results: Based on our results, 161 (63.4%) of patients were men. Half of patients were diagnosed with hypertension. 45% were diagnosed with diabetes, 41% had hyperlipidemia and 8.3% were smokers. Based on our findings, 18.1% of patients had abnormal MPI results. Our analytic results indicated that there is no statistically significant association between transient RV visualization, transient ischemic dilation or lung to heart ratio with 1st and 2nd minute HRR and EC.Conclusion: Considering lack of association between ETT indices and MPI findings, it seems that ETT is not adequately sensitive in predicting perfusion defects in MPI. Thus, it seems logical in some cases to ignore expenses of MPI and suggest it to patients before ETT based on clinical judgement.
The Role of 99mTc-antigranulocyte SPECT/CT In Community-Acquired Diabetic Foot Osteomyelitis: A Clinical Experience
Authors: Uçkay İlker , Hüllner Martin W. , Achermann Yvonne , Plate Andreas , Schöni Madlaina , Rosskopf Andrea , Berli Martin C.
Published: May 2021

Background:

Magnetic resonance imaging (MRI) is the actual gold standard for the radiological diagnosis of diabetic foot osteomyelitis (DFO).

Materials and Methods:

MRI is not always available and many patients have contraindications. We evaluated the clinical value of 99mTc-antigranulocyte SPECT/CT (AGS) in eight DFO patients who underwent MRI before.

Results:

The goal was to have a better clinical view on the extent of bone infection and to ameliorate the surgical approach for DFO. However, this additional scintigraphy did not change anything in the clinical approach.

Conclusion:

We shared our experience with AGS for clinical management of complex DFO cases.
Comparison of Clinical Characteristics, Laboratory Findings and Imaging Manifestations of COVID-19 in Sulfur Mustard-exposed Survivors and Others: a Case-control Study
Authors: Hosseiniara Reza , Hosseini Seyed Mohammad Javad , Mirhosseini Seyed Ali , Swann Jennifer , Nodoushan Majid Mirzaei , Sharti Mojtaba , Nezhad Hamidreza Ebrahimi , Amanpour Hassan , Shahriari Maryam , Farnoosh Gholamreza , Farajzadeh Mohsen Abbasi , Farahani Alireza Jalali
Published: May 2021

Objective:

The objective of this study is to determine if previous exposure to sulfur mustard
(SM) gas increases the pathogenesis of COVID-19 by comparing clinical characteristics, laboratory
findings, and imaging data between SM-exposed survivors and other patients with COVID-19.

Methods:

This case-control study was conducted in Baqiyatallah hospital, Tehran, Iran, from 26th Feb
– 26th March 2020. The case group composed of 60 SM-exposed survivors infected with COVID-19,
and the control group was composed of 60 patients with COVID-19. Groups were matched for demographic
(including age and gender) and comorbidity variables except for lung disease which was higher
in the case group. The clinical characteristics, laboratory findings, and imaging manifestations, as
well as outcomes, were compared between the two groups.

Results:

While the majority of patients in the case and control groups had at least one comorbidity like
diabetes, hypertension, or heart disease, only lung disease was significantly higher in the case than in
the control group (P=0.001). Patients in both groups displayed a variety of symptoms on arrival. Only
chest pain was significantly more frequent in case patients than those in the control group. The levels
of Neutrophils, ESR, BS, AST, LDH, and CRP in both groups were higher, and Na levels were lower
than the normal range. Neutrophils were significantly higher in the case than in the control group
(p=0.02). The BUN level was significantly lower in the control than in the case group (p=0.04). Other
laboratory findings were within their normal ranges and similar in both groups. Significantly more patients
in the case group showed early-stage opacities than those in the control group (p=.03). There
were no significant differences in treatment or outcomes between the two groups.

Conclusion:

Most clinical characteristics, outcomes, and laboratory findings of COVID-19 in SMexposed
survivors, were similar to those in the non-exposed. While these findings suggest that sulfur
mustard gas exposure does not significantly affect the prognosis of the disease, the limitations and
sample size of the current study may warrant additional investigations.
Artistic language of ihara saikaku
Authors: Qosimova Gulnorakhon Bakhtiyorjon qizi
Published: May 2021

The paper is devoted to the analysis of Ihara Saikaku’s artistic language as a novelist of the Japanese literature of Genroku period. Through the lingvo-poetic analysis the author illustrates characteristic features of Saikaku’s unique language.
The legal rooting of aut dedere principle in universal crimes
Authors: Al jaff Mohammed Rashid Hassan , Mawlood Awaz Asaf
Published: May 2021

in this research we are going to elaborate the legal frame of the principle of prosecute and investigate  core crimes as an obligation in international law .due to the fact that this principle is now the subject of the particular attention .as well as it was adopted as a rule in numerous treaties .and there is a crucial debate concerning the nature of this principle in international customary law . accordingly by elucidation and clarification of this principle and its definition we will examine its application in the Iraqi legal system as a pathway to universalism in criminalization process .thus we will clarify in the first part  the principle and its source also the philosophical aspect in addition to the legal basis in bilateral conventions .   the second part of the article will  offers some controversial issue with respect to the customary  nature of the principle .at least many suggestions are founded upon severla elements of this principle .
Predicting Intensive Care Unit Length of Stay and Mortality Using Patient Vital Signs: Machine Learning Model Development and Validation
Authors: Alghatani Khalid , Ammar Nariman , Rezgui Abdelmounaam , Shaban-Nejad Arash
Published: May 2021

Background

Patient monitoring is vital in all stages of care. In particular, intensive care unit (ICU) patient monitoring has the potential to reduce complications and morbidity, and to increase the quality of care by enabling hospitals to deliver higher-quality, cost-effective patient care, and improve the quality of medical services in the ICU.

Objective

We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an Intelligent Remote Patient Monitoring (IRPM) framework that monitors the health status of patients, and generates timely alerts, maneuver guidance, or reports when adverse medical conditions are predicted.

Methods

We utilized the publicly available Medical Information Mart for Intensive Care (MIMIC) database to extract ICU stay data for adult patients to build two prediction models: one for mortality prediction and another for ICU length of stay. For the mortality model, we applied six commonly used machine learning (ML) binary classification algorithms for predicting the discharge status (survived or not). For the length of stay model, we applied the same six ML algorithms for binary classification using the median patient population ICU stay of 2.64 days. For the regression-based classification, we used two ML algorithms for predicting the number of days. We built two variations of each prediction model: one using 12 baseline demographic and vital sign features, and the other based on our proposed quantiles approach, in which we use 21 extra features engineered from the baseline vital sign features, including their modified means, standard deviations, and quantile percentages.

Results

We could perform predictive modeling with minimal features while maintaining reasonable performance using the quantiles approach. The best accuracy achieved in the mortality model was approximately 89% using the random forest algorithm. The highest accuracy achieved in the length of stay model, based on the population median ICU stay (2.64 days), was approximately 65% using the random forest algorithm.

Conclusions

The novelty in our approach is that we built models to predict ICU length of stay and mortality with reasonable accuracy based on a combination of ML and the quantiles approach that utilizes only vital signs available from the patient’s profile without the need to use any external features. This approach is based on feature engineering of the vital signs by including their modified means, standard deviations, and quantile percentages of the original features, which provided a richer dataset to achieve better predictive power in our models.
Turn on, Tune in, and Drop out: Predictors of Attrition in a Prospective Observational Cohort Study on Psychedelic Use
Authors: Hübner Sebastian , Haijen Eline , Kaelen Mendel , Carhart-Harris Robin Lester , Kettner Hannes
Published: May 2021

Background

The resurgence of research and public interest in the positive psychological effects of psychedelics, together with advancements in digital data collection techniques, have brought forth a new type of research design, which involves prospectively gathering large-scale naturalistic data from psychedelic users; that is, before and after the use of a psychedelic compound. A methodological limitation of such studies is their high attrition rate, particularly owing to participants who stop responding after initial study enrollment. Importantly, study dropout can introduce systematic biases that may affect the interpretability of results.

Objective

Based on a previously collected sample (baseline n=654), here we investigated potential determinants of study attrition in web-based prospective studies on psychedelic use.

Methods

Logistic regression models were used to examine demographic, psychological trait and state, and psychedelic-specific predictors of dropout. Predictors were assessed 1 week before, 1 day after, and 2 weeks after psychedelic use, with attrition being defined as noncompletion of the key endpoint 4 weeks post experience.

Results

Predictors of attrition were found among demographic variables including age (β=0.024; P=.007) and educational levels, as well as personality traits, specifically conscientiousness (β=–0.079; P=.02) and extraversion (β=0.082; P=.01). Contrary to prior hypotheses, neither baseline attitudes toward psychedelics nor the intensity of acute challenging experiences were predictive of dropout.

Conclusions

The baseline predictors of attrition identified here are consistent with those reported in longitudinal studies in other scientific disciplines, suggesting their transdisciplinary relevance. Moreover, the lack of an association between attrition and psychedelic advocacy or negative drug experiences in our sample contextualizes concerns about problematic biases in these and related data.