bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance Analysis of the Village Unit Cooperative (KUD) “Suka Makmur” Using the Balanced Score Card
Authors: Siahaan Herlyna Novasari , Varwasih Mia Wananda , Nofitasari Rahmi
Published: November 2024

This study aims to analyse the performance of the village unit cooperative (KUD) “Suka Makmur” using the Balanced Scorecard instrument because cooperatives must be run with good management by implementing Good Corporate Governance (GCG). Therefore, it is necessary to measure the performance of cooperatives that focus on financial and non-financial performance. This research was conducted from July to October 2023 at the KUD “Suka Makmur”. Mixed methods are used for primary and secondary data. According to the results of research on customer and membership perspectives, it shows that the existing membership at the KUD “Suka Makmur” totals 1,978 people, where the 2021-2022 membership comparison has no cooperative members who have resigned. Second, the financial aspect shows that the results of financial ratios (liquidity, solvency, and profitability) of the KUD “Suka Makmur” are in good condition, the third aspect of the cooperative business is related to the business of buying and selling FFB, UKM Mart, agricultural production facilities unit and savings and loan unit. According to the fourth learning and growth perspective, there are efforts made by cooperatives aimed at improving the ability of cooperative human resources through cooperative training and education, as well as assistance from the Ministry of Cooperatives and the West Tanjung Jabung Cooperative Office.
Staying Happy During COVID-19: Analyzing Happiness Indicators Among Poultry Farmers in Malang Regency
Authors: Ta'in Anas , Nurahmi Sutraning , Damat
Published: November 2024

This study aims to examine the contribution of each happiness indicator, assess the overall happiness levels among laying hen and broiler chicken farmers, and analyze variations in happiness based on farm scale during the COVID-19 pandemic in Malang Regency. The research site was chosen through purposive sampling, as Malang Regency is a key center for poultry farming in East Java. Accidental sampling yielded 75 respondents, comprising 36 farmers with less than 5,000 livestock and 39 with more than 5,000. Results identified 16 valid indicators out of the 21 used in the study. The roles of each happiness indicator were as follows: education and skills (0.782), employment (0.780), health (0.632), family harmony (0.735), leisure availability (0.757), social relations (0.754), security conditions (0.584), happiness (0.716), absence of depression (0.793), optimism (0.867), empathy (0.570), independence (0.828), environmental mastery (0.815), self-development (0.598), positive relationships (0.615), and life goals (0.605). The overall happiness score for poultry farmers was 4.37, with laying hen farmers at 4.33 and broiler chicken farmers at 4.39, placing them in the "happy" category. No significant difference was observed in happiness levels between farmers with business scales below and above 5,000 livestock.
Argumentação na entrevista de seleção de emprego: um olhar sobre a modalização delimitadora
Authors: Adelino Francisca Janete da Silva , Nascimento Erivaldo Pereira do
Published: November 2024

Este artigo analisa a orientação argumentativa de modalizadores delimitadores no gênero entrevista de seleção de emprego. Os estudos sobre a modalização discursiva, a partir de Cervoni (1989), Castilho e Castilho (2002), Koch (2010), Neves (2011) e Nascimento e Silva (2012), entre outros, fundamentam essa investigação. Trata-se de uma pesquisa qualitativa, de cunho descritivo e interpretativo, cujo corpus é constituí­do por 22 entrevistas. Os resultados revelam que os modalizadores delimitadores são usados pelos locutores com os seguintes propósitos: a) indicar os limites de atuação do sentido do enunciado; b) situar as condições sob as quais o enunciado pode ser considerado; c) avaliar o conteúdo do enunciado; d) apontar condições para negociações; e) e, ainda, expressar certeza alicerçada no conhecimento compartilhado entre entrevistador e entrevistado. Assim, podemos afirmar que o fenômeno estudado atua como recurso argumentativo no gênero, pois além de situar limites em relação ao conteúdo no enunciado, apresenta traços de avaliação, faz referência a um dado especí­fico, orienta para uma interpretação desejada, e, também, estabelece uma negociação entre os interlocutores necessária à manutenção do diálogo.
"Redondo é sair do seu quadrado" (2017): análise semiótica de posts publicitários da skol no facebook
Authors: Camargo Gabriella Cristina Vaz , Ribeiro Thaí­s Borba
Published: November 2024

O objetivo principal deste artigo é investigar como se dá a relação entre os textos verbal, visual e verbo-visual que compõem um tipo especí­fico de anúncio publicitário, o post, avaliando em que medida eles funcionam na produção de um sentido global ao sincretizarem tais linguagens. Nesse sentido, os posts publicitários são tomados como objetos de análise deste estudo e compreendidos como textos sincréticos, conforme a Semiótica Discursiva, a partir das contribuições de Greimas (2014), Hjelmslev (1975), Floch (1985, 1986, 1995), Fiorin (2009) e Barros (2002, 2004). Foram coletados três posts publicados na página oficial da Skol, no Facebook, para a campanha de verão "Redondo é sair do seu quadrado", no perí­odo entre dezembro de 2016 e janeiro de 2017, analisando-se a constituição verbo-visual marcada pela sobreposição da linguagem verbal (os textos escritos na imagem e as legendas dos posts) e da linguagem visual (a composição figurativa das personagens e dos espaços nas imagens). Os resultados das análises apontam que a marca busca redimensionar sua própria imagem e abrangência de mercado na tentativa de adotar o discurso da inclusão e da quebra de padrões sociais ao incluir entre as estratégias enunciativas o texto de audiodescrição reforçado pela hashtag #PraCegoVer.
"O que Achamos do Filme 365 DNI": responsabilidade enunciativa e atos ilocucionários no gênero podcast
Authors: Sousa Francisco Diego , Bessa Maria Aparecida Porto , Bernardino Rosângela Alves dos Santos
Published: November 2024

Apesar da existência de diálogos empreendidos por profissionais dedicados a combater representações pejorativas relativas à mulher, ainda é comum encontrarmos, em nossa sociedade, discursos que propagam posições misóginas, sendo cada vez mais acentuados no universo das mí­dias digitais. Cientes da seriedade dessa problemática, propomo-nos a investigar a (não) assunção da responsabilidade enunciativa e os atos ilocucionários na construção desses discursos, especificamente no podcast intitulado "O que Achamos do Filme 365 DNI", disponí­vel no canal "Tranquilo Amor", no YouTube, em que três psicólogos e uma publicitária tecem opiniões sobre o referido filme. Para tanto, filiamo-nos teoricamente à Análise Textual dos Discursos proposta por Adam, à teoria do ponto de vista desenvolvida por Rabatel, à teoria dos atos de fala, introduzida por Austin, e à abordagem bakhtiniana de gênero. A análise mostrou que, no tocante à responsabilidade enunciativa, observada em função do gerenciamento das vozes, os locutores-enunciadores primeiros manifestam-se como coenunciadores dos pontos de vista de filósofos, psicanalistas, antropólogos, e evidenciam distanciamento com relação aos pontos de vista do senso comum, disseminados, por exemplo, na produção cinematográfica e em letras de música. Quanto aos atos ilocucionários, observamos sua natureza diretiva e enfática sobre os interlocutores, construindo a ideia de que o filme "365 DNI" é uma produção ruim em diferentes aspectos, sobretudo por reproduzir o discurso machista e misógino. Ao colocarmos em debate a polarização relativa aos discursos sobre a mulher, esperamos que este artigo contribua para o combate ao preconceito, ao machismo e a outros tipos de desvalorização da mulher.
Dificuldades e desafios na editoria cientí­fica em tempos de pandemia e ataques à pesquisa
Authors: Bessa José Cezinaldo Rocha
Published: November 2024

O volume reúne um conjunto de textos que reportam resultados de pesquisas que investigam os objetos texto e discurso por diferentes miradas teóricas. São contempladas investigações que abrangem temáticas das mais instigantes e atuais, dentre as quais destacamos tecnologias digitais, letramento crí­tico, BNCC, organização retórica em provas do ENEM, discursos polí­ticos, gêneros do discurso, texto e ensino e ensino de lí­nguas. Este volume traz, por exemplo, 03 textos que abordama Base Nacional Comum Curricular (BNCC), o que demonstra a atualidade e a pertinência das reflexões e contribuições que publicamos na nossa revista.
The Right to Education in the Convention on the Rights of Persons with Disabilities: How is it Implemented in Indonesia?
Authors: Santosa Satria Aji
Published: November 2024

This paper analyses the rights to education for persons with disabilities in Indonesia according to the existing national law and the Convention on the Rights of Persons With Disabilities. It is found that the persons with disabilities are still experiencing ambiguity when it comes to the implementation of their rights to education in Indonesia. This paper concludes that the form of protection of the rights for persons with disabilities to obtain education in Indonesia has not met the criteria set by the Convention on the Rights of Persons With Disabilities because there are still differences in access to education for persons with disabilities in Indonesia. The Indonesian government is suggested to implement the rights to education for persons with disabilities equally and non-discriminatory by ensuring an inclusive access to education and providing special educational facilities for persons with disabilities as regulated in legislation and the Convention on the Rights of Persons With Disabilities.
Legal Status of Climate Refugees: Is it Regulated in International Law?
Authors: Wattiheluw Azmi Julifa , Anwar Arman , Tuhulele Popi
Published: November 2024

Tulisan ini menganalisis fenomena pengungsi iklim, yakni orang yang bermigrasi akibat krisis iklim di negara asalnya dan penentuan status hukum, hak, dan perlindungannya dalam kerangka hukum internasional karena hukum internasional mendefinisikan pengungsi sebagai seseorang yang terpaksa meninggalkan negaranya. negara mereka karena penganiayaan, perang, atau kekerasan. Pengungsi mempunyai ketakutan yang beralasan akan penganiayaan karena ras, agama, kebangsaan, opini politik, atau keanggotaan dalam kelompok sosial tertentu. Kehadiran pengungsi iklim mendorong adanya prioritas tambahan bagi mereka yang terpaksa meninggalkan negara asalnya akibat krisis iklim. Tulisan ini menggunakan metode penelitian hukum normatif dengan mengkaji instrumen hukum internasional, buku, tesis, artikel jurnal, website, kamus hukum, dan ensiklopedia yang dikumpulkan melalui analisis hukum normatif kualitatif. Makalah ini menemukan bahwa ada beberapa pengaturan hukum internasional yang dapat memberikan perlindungan bagi pengungsi iklim berdasarkan konteks hak asasi manusia di mana status hukum pengungsi iklim disamakan dengan pengungsi yang didefinisikan dalam Konvensi Pengungsi 1951.
A Preliminary Sustainable Housing Development Framework for Rural Areas in Sarawak, Malaysia
Authors: Wong Shi Yee , Low Wai Wah , Soon Wong Kwong , Kan Fock-Kui
Published: November 2024

The Malaysian National Housing Policy 2018-2025 proposed different housing development strategies, specifically focusing on the urban areas, with relatively little investigation on housing development in rural areas. This research investigates the challenges of incorporating sustainability features into housing and strategies to moving forward which leads to the development of a preliminary sustainable housing framework in rural areas. Semi-structured interview was conducted with 13 rural area residents’ representatives and suppliers of housing materials who have more than ten years of experience in Sarawak. Content analysis was employed to analyse the collected data to further develop a framework related to sustainable housing development in rural areas. The proposed framework was validated with six experts who have 10-20 years of experience in rural areas through questionnaire. The findings revealed that accessibility issues, such as lack of proper transportation, and residents’ financial capacity, hindered sustainable housing development, as the houses in Sarawak rural areas are mostly built by the residents. A preliminary framework that includes collaboration between government, suppliers of housing materials, contractors and residents, was proposed for improving housing conditions in rural areas to ensure the durability of the traditional timber house as well as the newly constructed houses with bricks and cement. This research could assist the government in identifying residents’ housing needs, improving housing conditions and hence, enhancing residents’ quality of life.
A User-Centric CPTED-Based Approach to Investigate Physical Environmental Variables Influencing Perceived Security of Urban Park Users in Tiruchirappalli, India
Authors: Mehta Dherya , Gopalakrishnan Padmanaban
Published: November 2024

The link between Fear of Crime (FC) and physical environment and crime levels is referred to as Crime Prevention Through Environmental Design (CPTED). However, FC, irrespective of the level of crime through physical environmental features, can hinder people's access to urban parks. This study is a novel attempt to evaluate the Perceived Security (PS) related to fear of (theft, robbery) crime under the CPTED classification by assessing actual users' perceptions of multiple physical environmental variables within and around fifteen Tiruchirappalli urban parks. The objectively measured CPTED variables were documented through observations and measurements by the authors, whereas subjectively measured ones were assessed using actual users’ (n=524) perceptions. The results majorly highlight the significance of park design and landscape-based surveillance and park facilities and landscape-based maintenance variables towards predicting PS. The findings from this study can aid policymakers, park designers, and managers in adopting strategies that can enhance the PS of users, prioritise interventions, and engage residents in addressing specific design considerations.
Analysis of Barriers to Branding Waterfront City Makassar and Surabaya in Indonesia Using Interpretive Structural Modelling Approach
Authors: Maulana Syahrizal , Nasution Syukri Yusuf , Pramadi Yoka , Rusata Tatang , Hartanto Arief , Hendrix Tommy
Published: November 2024

Indonesia boasts the second-longest coastline in the world, with almost half of its cities surrounded by bodies of water such as lakes, rivers, and seas. The waterfront areas of these cities are vital and could be developed as a brand for each city. Two examples of such cities are Makassar and Surabaya, which have been developing waterfront city projects to increase tourism and improve city infrastructure. However, in practice, strengthening the branding of waterfront cities still faces various challenges. This research analyzes the barriers to strengthening city branding, specifically for waterfront cities in Makassar and Surabaya, using a case study method with a comparative descriptive design. The Interpretive Structural Modelling (ISM) approach was used to systematically analyze the barriers to branding waterfront cities and determine the best strategies for strengthening their branding. The identification of barriers revealed 15 barriers, which were summarized into five categories and structured into seven levels. Barriers with the highest value of driver power should be prioritized in problem-solving. Finally, this paper discusses strategies for strengthening waterfront city branding in Indonesia and presents the research findings, including recommendations for policy makers, urban planners, and stakeholders to collaboratively enhance the branding efforts and overcome the identified challenges.
Leaf shape and size variability of Dryas octopetala in the Central Great Caucasus (the Kazbegi region, Georgia) based on traditional and geometric morphometrics
Authors: Ekhvaia Jana , Abdaladze Otar , Jolokhava Tamar , Bakhia Arsen
Published: November 2024

While soil pH is known to be a key driver of plant species composition, we
still have a poor understanding of the quantification of the responses of
leaf traits to different soil types, especially in highly sensitive alpine
environments susceptible to global environmental changes. By combining
traditional and modern geometric morphometrics we aimed to bridge the
existing gap and determine whether certain leaf traits reliably separate
evergreen Dryas octopetala populations residing in the subalpine-alpine zone
of the Kazbegi region, in the eastern part of the Central Great Caucasus in
Georgia. To achieve this aim, three populations of D. octopetala were
analysed through traditional and, for the first time, modern geometric
morphometrics. Both methods revealed congruent results indicating
significant differences in leaf shape and size in locations with similar
climatic conditions but different soil pH environments (acid vs neutral to
slightly alkaline) thus suggesting that D. octopetala exhibits stronger leaf
morphological plasticity (wider and larger leaves vs narrower and smaller
leaves) to respond to changes in the soil pH gradient. In addition, modern
geometric morphometrics, with its high degree of precision as an accessible
and inexpensive method, could be advantageous for researchers and scientists
seeking to gain a deeper understanding of plant species? unique responses to
varying environmental conditions.
Clinopodium menthifolium subsp. menthifolium in the Central Balkan Peninsula - essential oil composition in relation to climatic conditions
Authors: Slavkovska Violeta , Zbiljic Milos , Stojanovic Danilo
Published: November 2024

The compositional dependency of the essential oil of Clinopodium menthifolium
subsp. menthifolium (Lamiaceae) on ecological conditions has not yet been
investigated. In pursuit of this objective, we assessed the quantity and
quality of the essential oil in plants from 11 natural populations from the
Central Balkans and one cultivated plant. In order to determine the
correlations between essential oil variations and environmental conditions,
each habitat was characterised by 36 climatic and 19 bioclimatic parameters.
Despite inhabiting diverse climatic zones, altitudes, and biogeographical
regions, no significant differences were observed in the yield and
qualitative and quantitative composition of the essential oils among the
analysed plants. All the samples exhibited essential oil yield ? 0.5%, V/w,
with piperitone epoxide as the major compound. Among the identified
compounds, only limonene and (E)-caryophyllene demonstrated dependence on
bioclimatic parameters. The bioclimatic parameters which influence the
presence of a larger number of compounds are annual temperature range and
the precipitation of the wettest quarter. The consistent quantity and
quality of the essential oils of C. menthifolium subsp. menthifolium
indicate their probable adaptive significance and could serve as
chemotaxonomic features of this taxon.
Red-list of moss species of Serbia: 2024 assessment
Authors: Sabovljevic Marko , Pantovic Jovana , Sirka Pavel , Vujicic Milorad , Sabovljevic Aneta , Papp Beáta
Published: November 2024

The new extinction risk assessments of the mosses of Serbia have been
completed. Based on the available data, 27.18% of Serbian moss flora (174
species) is under threat (status 2024). Nearly 20% (129 species) of Serbian
moss flora is considered to be Data Deficient (DD) and 5.16% (33 species)
Near Threatened (NT). These findings clearly indicate the urgent need for
field investigation and species biology research in order to define the
major threats and adequate conservation measures.
Propagation of Campanula bayerniana (Campanulaceae) by seeds as a reproduction model for the conservation of threatened small-seed plant species
Authors: Asatryan Anna , Shcherbakova Yekaterina , Rudov Alexander , Navasardyan Yevgenia
Published: November 2024

The in vitro seed propagation of small seeded Campanula species often incurs
complications in the manual handling of the tiny seed material from seed
sterilisation to seedling transplantation in soil. The lack of a simple and
effective protocol which minimises manual operations makes the propagation
of such species both challenging and inefficient. This study aimed to
develop a protocol for the seed reproduction of threatened Campanula and
other threatened small-seed plant species. The method was successfully
tested on Campanula bayerniana subsp. bayerniana. The saplings were
cultivated over a 5-month period through seed germination under in vitro
conditions followed by their transfer to containers with a soil mix. The
protocol employs small filter paper discs on which the seeds germinate and
continue their development in soil substrate until the full biodegradation
of the discs. The method involves surface treatment of the seeds with
potassium permanganate solution, thus avoiding additional washing phases and
direct contact with the seeds and seedlings, thereby preventing mechanical
damage. This also facilitates the handling of each seed separately,
minimising seed loss particularly when working with a small number of seeds.
This study is also the first known example of the ex situ propagation of
Campanula bayerniana.
A nomenclatural and taxonomic re-evaluation of neglected Centaurea candelabrum Hayek & Kosanin (sect. Acrocentron, Asteraceae) and related serpentine endemics from the Balkan Peninsula
Authors: Lakusic Dmitar , Kuzmanovic Nevena , Shuka Lulëzim , Novakovic Jelica , Vukojicic Snezana
Published: November 2024

Centaurea sect. Acrocentron comprises several taxonomically intricate groups
of taxa, including the Balkan endemic obligate serpentinophytes: C.
melanocephala, C. candelabrum and C. albertii. Despite its distinctive
morphological characteristics, C. candelabrum was considered conspecific
with C. melanocephala. A similar situation pertains to C. albertii, which
has largely been considered a synonym of C. melanocephala. Considering that
several recent floristic works treat these taxa as separate species
distributed in different serpentinite areas of the Balkans, the main
objectives of our study were to analyse the taxonomic and chorological
relationships between them, and to propose a new taxonomic concept. Our
study was based on an extensive revision of herbarium material, including
the type specimens, personal field data and observations of living plants.
Our comprehensive study showed that the plants previously recognised as C.
melanocephala from the Stolovi mountain in central Serbia and those
previously recognised as C. candelabrum from northern Albania deserve the
rank of distinct species. These species can be easily distinguished from
each other by a number of characters, including their general habitus, the
dimensions and shape of the basal leaves, and the indumentum of the
involucral bracts. Given the only slight differences observed between the
populations in Kosovo and Albania, the question of whether C. albertii is
conspecific with C. candelabrum or deserves an independent taxonomic status
remains unresolved until further detailed integrative studies are conducted.
In view of the clear differences in morphological and ecological
characteristics which exist within this group compared to other
representatives of sect. Acrocentron, we propose the separation of the
studied taxa into a separate C. melanocephala complex, as outlined in this
paper.
Physiological characterisation of aquatic traps in the epiphytic carnivorous plant Utricularia humboldtii
Authors: Adamec Lubomir
Published: November 2024

The suction traps of aquatic Utricularia species are discoid bladders, 1-6 mm
long, with their lumen isolated by a mobile trapdoor from the ambient
medium. Water is pumped out of the traps to maintain the negative pressure
in the reset traps. When a prey animal touches the sensory hairs on the
trapdoor it opens, the ambient water along with the prey is sucked inside
and the trapdoor is closed again. Utricularia humboldtii is a robust,
semiaquatic-epiphytic or terrestrial species from the generic section
Orchidioides from South America. The efficiency of its aquatic traps was
measured based on trap firing and resetting rates as well as changes in trap
thickness due to both mechanically stimulated and spontaneous firings using
an electronic sensor. The U. humboldtii traps exhibited relatively low
firing and resetting rates. These values are 2 to 20 times lower than those
in other aquatic Utricularia species reported in the literature. These
results together with the low aerobic respiration rate of sliced traps
indicate that the less efficient aquatic traps in U. humboldtii are
specialised for catching fine prey items in bromeliad water tanks. A marked
lag-period in trap resetting was found to occur during the first 30 min
after firing, contradicting the accepted concept of continuous water
pumping. Spontaneous trap firings were also observed with the same magnitude
as that in stimulated firings. This implies that spontaneous firings occur
consistently in all the tested aquatic Utricularia species. However,
although they relate to the continuous water pumping mechanism of the traps,
their physiological importance has not been fully elucidated.
Epidemiology and treatment outcome of nasopharyngeal carcinoma in a low-incidence population – a DAHANCA analysis in Denmark 2000–2018
Authors: Schiess Erik , Jensen Kristian H. , Kristensen Morten H. , Johansen Jørgen , Eriksen Jesper G. , Maare Christian , Andersen Maria , Farhadi Mohammad , Hansen Christian R. , Overgaard Jens , Hjalgrim Lisa L. , Lelkaitis Giedrius , Friborg Jeppe
Published: November 2024

Introduction: Nasopharyngeal carcinoma (NPC) is a rare disease and most studies have therefore been conducted in endemic areas. The aim of this study was to describe epidemiology and treatment outcomes of NPC in a population-based, non-endemic setting.
Material and methods: Patients with NPC diagnosed in Denmark from 2000 to 2018 were identified in the Danish Head and Neck Cancer Study Group (DAHANCA) database. Clinical records were reviewed to obtain missing data and confirm outcome, histological subtypes, Epstein-Barr virus (EBV)-status, prognostic factors, and treatment.
Results: NPC was identified in 394 patients corresponding to age-standardized incidence rates of 0.5 and 0.2 per 100,000 in men and women, respectively. The 5-year overall (OS) and disease-specific survival (DSS) were 56 and 66%. In multivariate analysis, stage, smoking, and histology affected both OS and DSS, as patients with undifferentiated carcinomas had superior outcomes. Tumor EBV-status was determined in 221 patients, of whom 160 (72%) tested positive. EBV-positivity was associated with an improved OS in univariate analysis, but not after adjustment for relevant clinical factors.
Interpretation: NPC is a rare malignancy in Denmark, and three in four patients have EBV-associated tumors. Tumor histology, smoking status, and stage, but not EBV-status, had independent prognostic impact on survival.
Cancer incidence following non-neoplastic medical conditions: a prospective population-based cohort study
Authors: Sipilä Lauri J. , Tanskanen Tomas , Heikkinen Sanna , Seppä Karri , Aavikko Mervi , Ravantti Janne , Aaltonen Lauri A. , Pitkäniemi Janne
Published: November 2024

Background and purpose: Many non-neoplastic diseases have been established to be tumorigenic, and cancers are sometimes misdiagnosed as non-neoplastic diseases. We conducted a comprehensive registry-based study of site-specific cancer diagnosis risk following the diagnosis of any preceding medical condition (PMC) encoded by the International Classification of Diseases (ICD)-10 classification.
Material and methods: We analyzed healthcare data and cancer data for a random population-based sample of 2.5 million individuals living in Finland on January 1, 2000. Hazard ratios for each PMC and cancer pair were estimated using piecewise constant hazard regression models. P-values were corrected for multiple testing with the Bonferroni method.
Results: Several lifestyle-related PMCs were associated with the risk of cancer diagnosis, exemplified by chronic obstructive pulmonary disease and subsequent lung cancer diagnosis risk (female hazard ratio [HR] = 9.91, 95% confidence interval [CI]: 9.18–19.7, p-adj. < 0.0001; male HR = 5.69, 95% CI: 5.43–5.96, p-adj. < 0.0001). Diagnosis risk of ill-defined cancers appeared to increase following diagnosis of Alzheimer’s disease (AD). We identified rare PMCs of potential interest.
Interpretation: A considerable proportion of the statistically significant associations were explainable by tobacco smoking and alcohol use. The enrichment of ill-defined cancer diagnoses in persons with AD, together with the overall inverse association between AD and cancer, may reflect underdiagnosis of cancer in this patient population. Our results provide a useful resource for research on the prevention and early detection of cancer.
Neuropathic Pain
Authors: R* Haider , A Mehdi , GK Das , Z Ahmed , S Zameer
Published: November 2024

Neuropathic pain, caused by damage to the nervous system, presents a major challenge in clinical care due to its complex nature. This review focuses on the mechanisms and current treatment strategies for neuropathic pain, particularly in conditions such as diabetes and other chronic neurological disorders. Neuropathic pain often manifests as spontaneous pain, hyperalgesia, and allodynia. Diagnosis involves a comprehensive patient history, physical examination, and specialized tests. Although pharmacologic treatments such as anticonvulsants and antidepressants are common, their efficacy is often limited by side effects. Non-pharmacologic therapies, including physical therapy and neuromodulation, provide additional relief. Emerging treatments, like nerve growth factor inhibitors, show promise in early trials. Personalized medicine, incorporating genetic and molecular insights, could revolutionize future treatment approaches. Continued research into these mechanisms is crucial for improving patient outcomes.
Biologically Active Natural Compounds in SARS-Cov-2 Adherence Prevention
Authors: M* Amirova , A Dadashova , N Melikova , F Mammаdova , I Kerimova , V Yagubova , A Orujov
Published: November 2024

Taking into account the information on the mechanism of of SARS-CoV-2 development, during treatment, it is advisable to pay attention to inhibition of viral replication; reduction hypoxia; elimination drug poisoning and toxic, allergic consequences; add antioxidant therapy to prevent formation of reactive oxygen species (ROS) at recovery phase and hook up anti-inflammatory therapy. This goal could be achieved through the administration of antioxidants with anti-viral properties. For example, using superoxide dismutase mimics metalloporphyrins, metallocorroles, Mn biliverdins, Mn cyclic polyamines, Mn salens, metal oxides/salts and inducers of antioxidant protection. It is also possible to increase the antioxidant enzymes genes expression or the activity of the enzyme itself. Patients taking antibiotics for SARS-CoV-2 were more susceptible to exacerbations due to opportunistic infections, so alternatives to antibiotics with high efficacy and well-absorbed antioxidant properties are more appropriate. In this regard, vitamin C, N-acetylcysteine, and glycine, as well as melatonin, quercetin, astaxanthin, glutathione, fat-soluble vitamins, polyphenols, unsaturated fatty acids, and a number of other substances with high anti-inflammatory effects exhibit positive effect.
A New Chemical Inhibitor to Mitigate Swelling of Sodium and Calcium Bentonite during Drilling Process
Authors: DA Osei
Published: November 2024

Clay swelling during drilling operations is one of the challenges faced in the oil industry. While both oil-based and syntheticbased muds have been successful at reducing clay swelling, the environmental concerns of oil-based muds and the high cost of synthetic-based muds limit their usage. Commercial water-based inhibitors like sodium chloride (NaCl), potassium chloride (KCl), cesium formate (CHCsO2), ammonium chloride (NH4Cl), and tetramethylammonium chloride (C4H12NCl-) are commonly used. However, some inhibitors have limitations, such as the toxicity of KCl, which according to the Environmental Protection Agency, cannot be used at concentrations higher than 5%. Other limitations include their impact on the rheology of drilling mud, cost (CHCsO2, C4H12NCl-), and their limited behaviour at high temperatures and pressures (NaCl). In this study, novel clay inhibitors for water-based drilling muds were characterized. A capillary suction timer (CST), a filtration time test, energy dispersive spectroscopy (EDS), and a scanning electron microscope (SEM) were used for the experiments. Testing was conducted on Na and Ca bentonite mixed with water-based drilling mud (WBDM) and commercial inhibitors, as well as novel inhibitors at 3%, 4%, and 5% concentrations.
Penerapan Model Project Based Learning Terhadap Kreativitas Mahasiswa Prodi PGSD Dalam Mengembangkan Silabus Pembelajaran
Authors: Maulida Rizky , Ginting Erwin
Published: November 2024

Pendidikan abad 21 merupakan Pendidikan yang salah satu tuntutannya adalah kreatifitas pada mahasiswa. Kreatifitas ini bisa dilakukan dengan menerapkan model pembelajaran yang mampu menstimulus kemampuan kreatifitas mahasiswa. Penelitian ini bertujuan untuk melihat kreatifitas mahasiswa yang diajarkan dengan menggunakan Project based learning (PjBL). Disain penelitian ini adalah penelitian eksperimen one shot case study dengan sampel penelitian 35 mahasiswa. Analisis data dilakukan dengan metode deskriptif. Hasil penelitian ini menunjukan mahasiswa yang diajarkan dengan model pembelajaran Project based learning (PjBL) memiliki persentase kreatifitas rata-rata 74% denagn kategori tinggi. beberapa kendala ditemui pada kegiatan pembelaajran seperti, pemahaman mahasiswa pada pembelajaran Project based learning (PjBL), perancangan proyek, distribusi tugas kelompo, dll. namun secara umum kendala yang ditemui mampu diselesaikan. Kesimpulan dari penelitian ini adalah pembelajaran dengan model pembelajaran Project based learning (PjBL) mampu menghasilkan kreatifitas yang tinggi pada mahasiswa.Keywords: Pembelajaran Proyek, Kreatifitas, PjBL
Quality assessment of oral health promotion contents regarding caries, periodontal disease, and oral cancer through websites using discern instruments: a cross-sectional study
Authors: Halim Muhammad Abdul , Suwargiani Anne Agustina , Aripin Dudi , Marhazlinda Jamaludin
Published: November 2024

ABSTRACTIntroduction: One way to improve public oral health is through conducting health promotion activities. As technology develops, the internet has been used as a medium for health promotion by presenting health content through websites. However, the use of these websites has the potential to provide inaccurate health information due to the flexibility of users in uploading health content without a prior regulatory process and review of the contents. This study aims to describe oral health promotion content quality through regarding caries, periodontal disease, and oral cancer websites using Discern Instruments. Methods: This study used the descriptive method with a cross-sectional approach. Samples were taken using the purposive sampling technique, with a total of 46 samples. The instrument consisted of 16 questions divided into three sections. The first section, comprising seven questions, focused on the reliability and accuracy of the presented health information. The second section, with eight questions, focused on the quality of information regarding treatment options. The final section, consisting of a single question, assessed the overall assessment based on the previous questions. The quality of the websites was assessed by two reviewers. The inter-rater reliability between the two reviewers was calculated using the Cohen’s Kappa test. Data presentation included frequency distribution, mean, and standard deviation. Results: In this study, 33.3% of caries websites had low quality and 66.6% had moderate quality. In periodontal disease, 33.3% of websites were of low quality, 60% were of moderate quality and 6.6% were of high quality. In oral cancer, 26.3% were of low quality and 73.6% were of medium quality.  Conclusion: The quality of dental and oral health promotion content on websites, assessed using the Discern Instruments, shows that most websites regarding caries, periodontal disease, and oral cancer have moderate quality, some have low quality, and only one website is of high quality.
Increasing mothers' knowledge, and attitudes, and children's oral hygiene index simplified (OHI-S): an experimental study on the “EKARINI” educational method
Authors: Eka Rini Willia Novita , Rusdi Muhammad , Siburian Jodion , Kalsum Ummi , Susilawati Sri
Published: November 2024

ABSTRACTIntroduction: The high incidence of dental caries in children is partly due to the lack of parental participation in estabilishing children's tooth-brushing habits. This research aims to see an increase in the variables tested in the EKARINI, an educational model on mothers’ knowledge, attitudes, and children's OHIS. Methods: This study employs an experimental design, collecting pretest and posttest data from mothers and their children following the intervention.  The intervention provided in this study involved the EKARINI educational model, which included a pre-test and post-test in the form of a questionnaire consisting of several questions about maternal knowledge and attitudes toward dental health, and the control group received standard education using media such as leaflets, videos, and phantom models. The sample consisted of two groups: an intervention group with 20 respondents and a control group with 20 respondents. Data analysis was conducted using either the independent t-test or the Mann-Whitney test. Results: The findings revealed a significant difference between the posttest scores of the intervention group and the control group The p-values indicate significant differences for each variable: knowledge (p = 0.006), attitude (p = 0.016), and OHIS (p = 0.010), showing that the EKARINI educational model effectively improved maternal knowledge, attitudes, and children's oral hygiene compared to the control group. Based on the average value, the group that received the educational model had a higher average value than the control group. Conclusion: The EKARINI educational model is in increasing mothers’ knowledge, attitudes, and better OHIS values.
Presentación dosier: Bibliotecología social: aportes, reflexiones y perspectivas desde América Latina y el Caribe - parte 1
Authors: Duque-Cardona Natalia , López Fernando A.
Published: November 2024

Presentación de dosier. Bibliotecología social: aportes, reflexiones y perspectivas desde América Latina y el Caribe - parte 1
La resistencia espacial: una práctica de biblioteca
Authors: Quintero López Dayro Leon
Published: November 2024

El presente artículo parte de una investigación en la que se aborda el problema de los procesos de resistencia que en América Latina han permitido la configuración y el funcionamiento de las bibliotecas como respuesta a las problemáticas sociales. En razón de ello, se ubica conceptualmente en la geografía y en particular en el espacio, para desde allí interpelar la bibliotecología en la comprensión de los fenómenos sociales, desencadenando con ello un ejercicio metodológico de corte cualitativo con análisis de contenido en una perspectiva crítica de tal modo que la lectura y el análisis permitan situar el decir en el espacio y el espacio del decir de la biblioteca como parte de la resistencia espacial de los bibliotecarios y las bibliotecarias.
El Boletín de la Biblioteca Pública de la Provincia de Buenos Aires: un instrumento estratégico de gestión y exhibición (1899-1905)
Authors: Dorta Ayelén
Published: November 2024

Se elabora una caracterización del Boletín de la Biblioteca Pública de la Provincia de Buenos Aires, editado entre 1899 y 1905 por Luis Ricardo Fors en el marco de sus funciones como director de la biblioteca situada en La Plata. Se parte de una breve inscripción del órgano periódico en el campo revisteril decimonónico para, luego, poner la mirada sobre los aspectos materiales y de contenido que configuraron su identidad. A modo de conclusión, se sostiene que el Boletín se constituyó como un hito en la historia institucional del espacio bibliotecario y en la historia de la bibliotecología argentina como disciplina en emergencia. En paralelo, se argumenta que Fors hizo un empleo estratégico de este dispositivo, tanto en términos institucionales como personales.
¿Emprendedores? La ilusión de la independencia
Authors: Ferreyra Florencia Ester , Padín Mariano
Published: November 2024

Reseña de Emprendedores Ya!: Capitalismo de plataformas en Uruguay por N. Marrero (Coord.), A. González, P. Leguisamo y N. López
Improving the Computational Thinking Abilities of Junior High School Students Through Problem-Based Learning
Authors: Romadani Moh. Nafis Husen , Ariyanti Gregoria , Winarsih
Published: November 2024

Computational Thinking is a crucial skill that students must master in the 21st century. Computational Thinking encompasses a systematic process that enables individuals to formulate problems, develop strategies, and find effective, efficient, and reusable solutions. This research aims to enhance students' Computational Thinking abilities through the application of the Problem-Based Learning (PBL) model, which is effective in facilitating active learning and problem-solving. The methodology used in this study is Classroom Action Research (CAR) with a spiral approach developed by Stephen Kemmis and Robin McTaggart. Data collection is conducted through post-tests administered at the end of each cycle phase. The obtained data are analyzed using a designed assessment rubric, wherein students are categorized based on their Computational Thinking abilities and foundational Computational Thinking skills. The results indicate that by the end of Cycle II,  of students achieved a moderate to high level of Computational Thinking ability. These findings affirm that the implementation of the Problem-Based Learning learning model can significantly improve students' Computational Thinking skills.
The Padlet Media Design Based on Bima Local Literature to Improve Student Writing Skills
Authors: Arwan  , Suryaningsih Sri
Published: November 2024

This research aims to improve students' writing skills through the use of Padlet media which is integrated with local wisdom of Bima regional literature. The background of this research is based on the low writing ability of students caused by monotonous traditional learning methods and the lack of use of interactive media. This research uses the Research and Development (R&D) method with the ADDIE (Analysis, Design, Development, Implementation, and Evaluation) development model. Local literature, such as folklore and poetry, is integrated into Padlet's platform as teaching materials to provide relevant cultural context for students. The participants in this study are 30 students of the Indonesian Language and Literature Education Study Program at STKIP Harapan Bima. The results of the study showed a significant improvement in students' writing skills after the use of Padlet based on local wisdom. The average writing score of students increased by 25%, especially in the aspects of cohesion, coherence, and idea development. In addition, students also reported increased motivation and active involvement in writing learning through Padlet's collaborative features, such as writing sharing and feedback. However, there are several technical obstacles faced, such as limited internet access and lack of digital literacy among students. The results of this study have implications that the integration of digital technology and local wisdom can be an innovative strategy in improving students' writing skills, as well as fostering their cultural awareness.
3 korzyści dla jelit – prebiotyk, probiotyk, postbiotyk
Authors: Waśko-Czopnik Dorota
Published: November 2024

Choroby jelit, zarówno czynnościowe, jak i zapalne, zaczynają stanowić globalny problem zdrowotny. Ich etiologia jest wieloczynnikowa, diagnostyka bywa trudna, złożona i ma na celu nie tylko potwierdzenie rozpoznania, ale wykluczenie przede wszystkim zmian organicznych. Spektrum dolegliwości, zwłaszcza w zaburzeniach czynnościowych, jest szerokie i niestałe, dlatego stosujemy leczenie objawowe, nakierowane na aktualne dolegliwości chorego. Jedną z ważnych przyczyn chorób jelit jest zaburzenie osi mózgowo-jelitowej, co przekłada się na funkcjonowanie mikrobioty jelitowej. Odpowiednia dbałość o mikrobiom, stosowanie prebiotyku i postbiotyku dla zachowania jego równowagi oraz suplementacja odpowiednio przebadanym probiotykiem to kluczowe elementy utrzymania homeostazy jelit.
Lewodropropizyna – czy skład leku ma znaczenie?
Authors: Sybilski Adam J.
Published: November 2024

Kaszel jest najczęstszym objawem chorób układu oddechowego, a odruch kaszlowy jednym z podstawowych fizjologicznych mechanizmów ułatwiających oczyszczanie dróg oddechowych. Wskazania do stosowania leków przeciwkaszlowych są ograniczone i dotyczą wyłącznie suchego, uporczywego kaszlu. Jednak badania pokazują, że stosowanie leków przeciwkaszlowych jest skuteczne. Wśród leków przeciwkaszlowych szczególne miejsce zajmuje lewodropropizyna. Jest nieopioidowym środkiem przeciwkaszlowym, działającym obwodowo. Metaanalizy udowodniły skuteczność zarówno u dzieci, jak i dorosłych, wykazując statystycznie istotnie lepsze wyniki w porównaniu z lekami przeciwkaszlowymi działającymi ośrodkowo pod względem skuteczności w zmniejszaniu intensywności kaszlu, jego częstości i nocnych wybudzeń. Cechy, jakie powinien mieć idealny lek dla dzieci to: skuteczność, bezpieczeństwo, doświadczenie ze stosowaniem preparatu, postać odpowiednia do wieku i możliwości pacjenta, precyzyjnie określone dawkowanie, brak zawartości cukru w syropie oraz alkoholu i barwników, dobry smak i prosty sposób dawkowania. Jest taki preparat.
Zgaga – czym, kiedy i jak złagodzić?
Authors: Waśko-Czopnik Dorota
Published: November 2024

Jednym z najczęściej zgłaszanych przez pacjentów schorzeń jest zgaga – pieczenie i palenie wzdłuż przełyku. Stanowi ona jeden z głównych objawów choroby refluksowej przełyku, ale może pojawiać się także incydentalnie. W zależności od częstości występowania dolegliwości, czasu ich trwania oraz nasilenia proponowane jest odmienne postępowanie, które ma na celu szybkie łagodzenie zgagi, gojenie potencjalnych zmian zapalnych przełyku lub doraźne zniesienie odczucia pieczenia w przełyku, jeśli nie występuje ono często lub stale, a tylko w określonych sytuacjach, np. po błędach dietetycznych. Samoleczenie pacjentów powinno być ograniczone do 2 tygodni, a przy najmniejszych wątpliwościach czy przy występowaniu objawów alarmowych zawsze należy wykonać badania dodatkowe. Leczenie inhibitorami pompy protonowej powinno być ograniczone do 4–8 tygodni, w razie niepowodzenia pacjent również powinien być skierowany do specjalisty. Doraźne stosowanie famotydyny, alkinianów i alginianów może być skuteczne przy objawach epizodycznych.
Eplerenon – filar terapii niewydolności serca
Authors: Krzowski Bartosz , Grabowski Marcin
Published: November 2024

Niewydolność serca jest główną przyczyną zgonów w Polsce i na świecie. Ponadto liczne hospitalizacje pacjentów z niewydolnością serca wiążą się z bardzo dużym obciążeniem finansowym dla systemów opieki zdrowotnej. W wytycznych Europejskiego Towarzystwa Kardiologicznego przedstawiono dokładne rekomendacje dotyczące leczenia pacjentów z niewydolnością serca uwzględniające konkretne molekuły. Dodatkowo, coraz więcej uwagi poświęca się stosowaniu leków w optymalnych dawkach. Najnowsze dane potwierdzają zasadność stosowania większych dawek leków rekomendowanych w wytycznych.