bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of Hand Joint Symptoms in Androgen Deprivation Therapy Among Japanese Patients with Prostate Cancer
Authors: Inoue Shogo , Hayashi Tetsutaro , Teishima Jun , Matsubara Akio
Published: December 2021

Purpose:

The current trends in favor of androgen deprivation therapy (ADT) for nonmetastatic prostate cancer at the stage of biochemical recurrence or increasing prostate-specific antigen levels raise the issue of exposing asymptomatic patients to potential adverse effects over the longer term. The aim of this study is to assess the hand joint symptoms caused by ADT in Japanese patients with prostate cancer.

Materials and Methods:

We retrospectively reviewed and performed a cross-sectional survey of hand joint symptoms in patients receiving ADT for prostate cancer. The results were compared with a control group of patients with prostate cancer that was hormone-naïve group. In total, there were 279 Japanese patients with prostate cancer, of whom 150 patients were ADT treated and 129 patients were hormone naïve. Patients completed a three-item self-administered questionnaire assessing the presence of hand joint symptoms that started or worsened after initiating ADT.

Results:

A statistically significant difference was found between the incidence rates of hand joint symptoms of both groups (P = 0.0056). There was a statistically significant difference in the incidence rates of hand joint pain (P = 0.0273). However, the incidence rates of hand numbness (P = 0.0576) and hand muscle weakness (P = 0.1098) between both groups were not significantly different.

Conclusion:

Our cross-sectional study demonstrated that patients receiving ADT for prostate cancer show significant hand joint symptoms compared to hormone-naïve patients. Consequently, for patients receiving ADT who suffer from hand joint symptoms, we must consider the adverse effects of ADT.
Comparative Analysis of Robot-Assisted, Laparoscopic, and Open Radical Prostatectomy Regarding Lower Urinary Tract Symptoms
Authors: Inoue Shogo , Hayashi Tetsutaro , Teishima Jun , Matsubara Akio
Published: December 2021

Purpose:

This study aims to assess lower urinary tract symptoms (LUTS) after radical prostatectomy (RP) and compare longitudinally the short-time LUTS changes of three techniques: robot-assisted RP (RARP), laparoscopic RP (LRP), and open RP (ORP).

Materials and Methods:

We reviewed prospectively the collected longitudinal data on the International Prostate Symptom Score (IPSS) from patients who performed RP for localized prostate cancer. One-year longitudinal data (preoperatively and at postoperative 3, 6, and 12 months) on IPSS were available for 322 patients. The number of patients was 231 for RARP, 42 for LRP, and 49 for ORP. LUTS was assessed on the basis of the IPSS and the IPSS quality of life (QOL) score.

Results:

The IPSS and IPSS related QOL scores were significantly improved over the baseline score not for the LRP and ORP but for the RARP. For patients with moderate to severe LUTS preoperatively, the RARP group immediately improved in terms of preoperative LUTS differently from both LRP and ORP groups. Only RARP significantly improved in terms of voiding symptom composites (VSC) differently from both LRP and ORP procedures. However, none of the procedures changed in terms of storage symptom composites (SSC) longitudinally.

Conclusions:

The improvement of LUTS for RARP may contribute to the improvement of not only SSC but also VSC.
Comparing the Predictive Values of Diameter-Axial-Polar and Renal Scores for Long-Term Trifecta Outcomes in Robot-Assisted Partial Nephrectomy for Renal Cell Carcinoma
Authors: Lien Chi Chih , Chiang Chi Hung , Lu Yu Chuan , Chang Hong Chiang , Huang Chao Yuan
Published: December 2021

Purpose:

Few studies have reported the value of the diameter-axial-polar (DAP) score in robot-assisted partial nephrectomy (RaPN) for renal cell carcinoma (RCC) and sequentially compare DAP and RENAL nephrometry score to predict long-term surgical, oncological, and functional outcomes of RaPN for renal cancer. This study demonstrated that the DAP score is effective enough to predict long-term trifecta outcomes of RaPN.

Materials and Methods:

We retrospectively collected clinical data of 108 patients with pathologically confirmed RCC who received RaPN by a single surgeon during 2012–2017. The patients were stratified into low, intermediate, and high complexities according to the RENAL and DAP scoring systems. We analyzed warm ischemia time (WIT), cancer-specific survival, radiographic progression-free survival, positive rate of surgical margin, renal function from the preoperative period to postoperative 1st/6th month, and postoperative complications.

Results:

The median follow-up period was 36 months. The 3-year cancer-specific survival rate and 3-year radiographic progression-free survival were 98.4% and 95.2%, respectively. Four patients (3.6%) had positive surgical margins. The largest decrease of renal functions from pre- to postoperative 6th month was noted in the intermediate DAP score group. No difference was observed between the DAP and RENAL scores in terms of WIT in 25 min, positive margin, complication, 3-year radiographic local recurrence, and chronic kidney disease (CKD) change, but a significant difference was observed in WIT in 20 min (area under the curve of DAP vs. RENAL = 0.81 vs. 0.54, P = 0.03). Age is an independent factor for progression to CKD after RaPN (odds ratio = 1.054, 95% confidence interval = 1.008–1.102, P = 0.022). Complications occurred in 22 patients (20.4%), and the most common postoperative complications were bleeding (12.2%), postoperative fever (0.5%), and urinary leakage (0.3%).

Conclusion:

The DAP score is an easy and effective tool for predicting perioperative outcomes of RaPN, especially in WIT in 20 min.
Tubular Ectasia of the Rete Testis
Authors: Chun Hui-Ming
Published: December 2021

A 60-year-old male reported a painless left scrotal mass for months. The testicle was removed due to the fact that malignancy could not be excluded from physical examination, tumor markers, or scrotal imaging. Afterward, further pathological examinations diagnosed the patient's condition as tubular ectasia of the rete testis (TERT) rather than malignancy. TERT is a rare benign lesion that may be mistaken for malignant tumors at first glance. However, distinguishing diagnoses can be made with a combination of sonography and magnetic resonance imaging without much difficulty. That is why it is highly recommended to consider this condition before confirming the final diagnosis of similar cases.
The Impact of Population Lockdown on the Referral Pattern for Urology in a COVID-19 Designated Tertiary Hospital in Malaysia
Authors: Amat Norshuhada , Philip Eleanor F. , Chai Chu Ann , Yeoh Wei Sien , Lim Jasmine , Fadzli Ahmad Nazran , Kuppusamy Shanggar , Ong Teng Aik
Published: December 2021

Purpose:

Once COVID-19 was first reported in Wuhan, China, in December 2019, it has rapidly spread worldwide. The Malaysian Government had taken an early measure by introducing the movement control order (MCO), which is a form of lockdown. This study aims at describing the referral pattern for urology in a COVID-19 designated tertiary hospital throughout the MCO period.

Materials and Methods:

All urology referrals received from March 18, 2020 to April 28, 2020 (i.e., during the MCO period) were included and assessed prospectively. For comparison, a retrospective study covering the period from February 1, 2020 to March 17, 2020 (i.e. pre-MCO period) was conducted. Parameters measured and compared include sources of referral, type of cases, outcomes, admission status, and COVID-19 status of patients referred.

Results:

The majority of referrals for urology were received from the emergency department during MCO (42.9%), followed by the medical ward (28.6%) and surgical ward (2.3%). In terms of the type of cases referred, during the MCO, the highest number of hematuria cases (22.5%) was received and a high number of Benign Prostate Hypertrophy (BPH) and urethral stricture cases (18.8%). Conservative measures remain the most commonly adopted outcomes/management for both pre and during MCO. The number of admissions required for urology referral showed a slight difference between pre and during MCO.

Conclusion:

The workload of urology referral in a COVID-19 designated tertiary hospital did not change despite MCO. This supports that the urology team still has an important role to play as a subspecialty unit in managing urology emergencies, even when elective surgeries and procedures are being reduced or rescheduled.
Noticing: Una revisión bibliográfica sobre los orígenes y perspectivas actuales
Authors: López Ledher M.
Published: December 2021

Esta revisión bibliográfica parte de la relevancia del constructo del noticing del profesor en la Educación Matemática y pretende explorar el concepto del noticing a partir de las obras que dan origen a su estudio en nuestra área y describir las perspectivas teóricas que se encuentran en sus bases y las vertientes investigativas que actualmente derivan de estas. El método utilizado para esta revisión sistemática de la literatura ha sido citation-based study (estudio basado en citas) que ofrece unos procedimientos bien definidos de recolección de datos, considerando cuatro categorías para las publicaciones revisadas: citadas, co-citadas, citantes y co-citantes. Se parte de una búsqueda en Google Académico utilizando como palabra clave “noticing”, posteriormente, se trabaja con la información de citación de la base Web of Science. El análisis de datos se realiza con la herramienta Bibliometrix que permite determinar las relaciones entre documentos y sus citaciones. La selección final considera 44 publicaciones que proporcionan información sobre los orígenes de la conceptualización del noticing desde tres posturas teóricas diferentes y las distintas perspectivas emergentes. Se concluye con algunas preguntas abiertas y proyecciones para futuros estudios en el tema.
Distribution of financial resources by areas of investments in the human capital of the region
Authors:   Vladivostok State University of Economics and Service, Mazelis Lev S. , Krasko Andrey A. ,   Vladivostok State University of Economics and Service, Krasova Elena V. ,   Vladivostok State University of Economics and Service
Published: December 2021

Introduction. The study has been conducted within the framework of the urgent scientific and practical task of accumulation and development of human capital of Russian regions. Under the conditions of risks and limited resources, the regional management faces the task of optimal distribution of financial resources invested in the development of human capital and improvement of the quality of life. The study aims to build and test the dynamic optimization model of financial resources distribution by areas of investment in human capital through the example of the Primorye Territory (Russian Federation). Materials and methods. The multi-period economic and mathematical model describes the influence of the volumes and structure of public and private investments on the regional human capital in the form of recurrent dependencies. The target function of the model is an integrated index of achieving the objectives for the development of human capital in the region. The model is a mathematical programming problem, the optimization variables are the shares of investment resources distributed by investment areas and years. Results. In a practical sense, the proposed model is a management tool for searching the optimal structure of investments in human capital by areas of investment and periods. Based on the annual results of modeling and numerical calculations through the example of the Primorye Territory (Russian Federation), the structure of the investments that allow advancing in the achievement of target values of strategic indicators in the field of human capital development is offered. Conclusion. In the long term, the achievement of target indicators will be facilitated by a more even structure of investments in the following areas: along with education and health care, it is advisable to increase investments in other areas, first of all, in the issues of national importance, national security, public order, and social policy.
POSITIONING FLOWER BOUQUET DENGAN MULTIDIMENSIONAL SCALING BERDASARKAN PERSEPSI KONSUMEN DI LACHERIE FLORIST
Authors: Mariana Christy Dwita , Octavalery Yolanda , Yusuf Dionisius
Published: December 2021

The purpose of this study is to determine the position of flower bouquet on ​​the consumer perception in Lacherie Florist by using multidimensional scaling analysis (MDS). The sample in this research were 104 respondents of Lacherie Florist. Data collection used a questionnaire through Google forms. The validity test results stated that all statements were valid as well as the reliability test showed that all parameters were reliable. The results obtained from the bouquet flower were divided into four different positioning groups based on consumer perception. The results indicated that (1) Bloom Box was most different from other types of bouquet flower (2) Bloom Bag, Artificial Flowers and Snack Bouquet have similarities because they were in the same quadrant (3) Mixed Money and Flowers and Money Bouquet were the most similar type because of the position closest to each other. (4) Fresh flowers have similarities with Mix Money Bouquet and Flowers but located in different quadrant.Keywords: Bouquet flower, consumer, perception, multidimensional scaling, positioning
Dijital Anlatılarda Erkeklik Temsilleri: Onur Saylak'ın Şahsiyet Dizisinin Göstergebilimsel Çözümlemesi
Authors: BARIŞ Baran
Published: December 2021

Toplumsal cinsiyet çalışmaları ilk dönemlerinde kadın kimliğine odaklanırken ardılı olan çalışmalarda erkekliğin inşası üzerine de çözümlemeler yapılmaya başlanmıştır. Elde edilen bulgular edebiyattan sinemaya birçok disiplinde yapılan araştırmalara katkı sunmuştur. Erkekliğin inşası, sinema ve televizyonda ele alındığında baş anlatı kişisi olan erkeklerin R. W. Connell’ın “hegemonik erkeklik” kavramıyla açıkladığı erkekliğin temsilcileri oldukları görülmüştür. Bu geleneksel anlatılarda, erkek anlatı kişileri, başta kadınlar olmak üzere yaşamlarındaki insanlar üzerinde doğrudan egemenlik kurmuş ya da kadınların kurtarıcıları olarak konumlandırılarak kahramanlaştırılmıştır. Bu çalışmanın amacı, dijital platformlarda yayınlanan anlatılarda erkeklik temsillerinde bir farklılık olup olmadığını göstergebilimsel yöntem çerçevesinde ortaya çıkarmaktır. Çalışmanın veri tabanını Onur Saylak’ın yönettiği Şahsiyet dizisi oluşturmaktadır. Anlatıda hegemonik erkekliğin dışında, toplumsal cinsiyet rejiminin erkeklerden beklediği toplumsal cinsiyet rollerine uymayan ve “kahraman” olmayan, yenilebileceği de gösterilen Agâh Beyoğlu, Ateş Arbay ve Firuz adlı erkek karakterlerin eylemleri, eyleyen şeması kapsamında incelenmektedir. Anlatı kişilerinin eylemlerinin başarısızlıkla sonuçlanmasında, eşitsizlik üzerine kurulan ataerkil yapının doğrudan etkisi olduğu ortaya çıkmıştır. Bununla birlikte ataerkil yapının hegemonik erkeklik dışındaki erkeklik biçimlerine de yaptırımlar uyguladığı görülmüştür.
COMPARATIVE STUDY OF EFFICACY OF SHATAVARI GHRUTA ANJANA AND ERANDA TAILA ANJANA IN THE MANAGEMENT OF VISUAL DISPLAY TERMINAL SYNDROME
Authors: Dubey Vijay , Salvi S.S.
Published: December 2021

This study was conducted to evaluate the efficacy of Shatavari ghutra Anjana and Eranda taila anjana in the management of the visual display syndrome. For this work patients attending the netraroga (oph- thalmology) OPD at the hospital attached to Tilak Ayurveda Mahavidyalaya, Pune (Maharashtra) was selected based on the inclusion and exclusion criteria of the study. Ethical clearance was accredited by the institutional ethical committee of the institute and written consent from all the selected patients was taken before the treatment. The selected patients were randomly divided into two groups. Group A was given Shatavari ghruta anjana in each eye one time a day for one month and group B was given Eranda taila anjana in each eye one time a day for one month. The clinical data collected and compiled from this clinical trial was sorted out processed by implying various statistical methods and it was found that Group A showed comparatively better results in redness of eyes and eye irritation.
Keywords: Shatavari ghruta anjana, Eranda taila anjana, visual display syndrome.
CRITICAL UNDERSTANDING OF MUTRA UTPATHI ACCORDING TO AYURVEDA
Authors: Baby Madona , Kulkarni Prathibha
Published: December 2021

Ayurveda is mainly based on dosha, dhatu and mala. Mala are the substances or waste matters That are excreted out of the body. They are by-products formed as a result of various physiological activities happening inside the body. Purisha, Mutra and Sweda are considered as the main excretory product of the body and called mala. Urine formation is one of the important physiological activities of the human body in which Mutravaha Moola and waste products of Ahara Rasa contribute significantly. Basti, Mutravaha Srotansi, Vrikka, Mutravaha Nadies, Mutravaha Dhamanis and Mutravaha Sira, etc. Are major body parts which play a significant role in the process of urine formation. While modern science described the urinary bladder, nephrons, kidneys, ureters and urethra, etc as vital parts of urine formations. This article tries to critically review the formation of urine according to Ayurveda.
Keywords: Mala, Mutra, Mutravaha Srothas, urine formation
A CLINICAL STUDY OF DEVDALI HIMA NASYA AND DRONPUSHPI SWARASA ANJANA IN KAMALA (JAUNDICE)
Authors: Kanwar Rekha , Sharma Mahesh Kumar , Sharma Gyan Prakash
Published: December 2021

Most people have become used to spicy fast-food day by day. This has taken human beings far away from nature. Nowadays alcohol consumption is also increasing day by day. Ayurvedic texts have mentioned hepatocellular jaundice as Kamala. Due to frequent intake of Pittakara Aahara (spicy and hot food), it leads to vitiation of Pitta Dosha and Virechana1 (purgation) is the first line of treatment for Pittadushti. Ayurvedic line of management Ac- cording to lolimbraj (Vaidya jivana)2 i.e., Nasya therapy and According to Chakradatta Anjana3 therapy in addi- tion with above mentioned take 3 gm Triphala Churna with Lukewarm water at bedtime for Koshta shuddhi. Nasya and Anjana both are successful in Kamala by removing toxic waste from the body, and by correcting Agni (digestive fire). In our ancient classics, single drugs along with compound drugs have been mentioned in Kamala. These drugs have Kamalahara properties. This results in better circulation and nourishment of the organs and the diseases will subside. Kamala is a disease caused by an overabundance of Mala Ranjak Pitta. Nasya cleanses and energies the tissues and organs of the head and neck. Shodhan Nasya is a form of Nasya that promotes secretions and removes toxins from the body. Devadali Phal Nasya is a form of Shodhan, particularly Rechna Nasya, that causes accumulated Mala Ranjak Pitta to be excreted through the nose. Nasya is referred to as "Nastah Pracchar- dan" by Charaka4. It means Nasya is shodhan karma, which explains Nasya's position at the systemic level and why sr. bilirubin levels fall. Dronpushpi is Doşakarma Kaphavātaśamaka, Pittasamśodhaka Property.It is having Katu, Lavaņa, Madhura Rasa. It is laxative, angmintic, stimulant and febrifuge. The swarasa of this herb is ap- plied as a collyrium (natrănjana) in case of jaundice.
Keywords: Jaundice, Kamala, Pitta Dushti, Nasya, Anjana, LFT.
AYURVEDIC MANAGEMENT OF GRIDHRASI (SCIATICA)
Authors: Rao Anshika , Kumari Sunita
Published: December 2021

In the contemporary era, human society is leading a mechanical life with a sedentary lifestyle, precariously busy schedule, constant work without rest, night shift, alarming anxiety and stress in the work field, drastic changes in the environment etc. All these cause prevalence of Vatavyadhi(disorders due to Vata dosha) in this modern era. Among the different Vatavyadhi (disorders due to Vata), the most affected one is Gridhrasi (sciatica) which is characterized by low backache radiating to one or both the lower limbs. In addition to the above-mentioned caus- es, constant work schedule in an improper sitting posture, travelling long distances by vehicles, lifting of heavy objects, trauma to the low back region are the precipitating factors of Gridhrasi. The causes, signs and symptoms explained by different Acharyas have more relevance to the present situation. The presentation of Gridhrasi var- ies from person to person due to changes in Nidana(causative factors), and Samprapti (pathogenesis). Close ob- servation and thorough knowledge of our classics make the diagnosis and treatment of Gridhrasi easier. So, the present article tries to explain the Lakshana (symptoms) and treatment of Gridhrasi which will ensure a simpler and more effective treatment of the cases.
Keywords: VataVyadhi; Gridhrasi; Nidana; Samprapti; Lakshana; Treatment.
MARMA THERAPY: A NEW APPROACH OF AYURVEDA IN POST-COVID-19 STRESS MANAGEMENT
Authors: Singh Shailesh , Sharma D. K. , Sharma J. K. , Das Sharma Purushottam
Published: December 2021

Introduction: Ayurveda is an ancient science of medicine and surgery, here many of the treatment procedures are described for combat diseases, i.e., Ksharkarma (procedure with the help of base), Agnikarma (procedure with the help of fire), Siravedhan (procedure with the help of puncturing blood vessels), Panchkarma (purification proce- dure) etc. In this science Marma (vital point) therapy is like a blessing to a human being. It is a stimulation therapy of specific points. Now these days, stress arises as a major problem in COVID-19 recovered patients. It is very common to all age groups. Major causes are lack of proper classes of students, unemployment, lack of social inter- action due to isolation and health status anxiety during COVID-19 infection. It arises during and post COVID-19
but especially in the post period of infection. In stress, Marma therapy has an important role because it helps to maintain the equilibrium of the body by working on body humour. Objective: To provide costless, chemical-free and effective treatment for post-COVID-19 patients. Data Source: Relevant various Ayurvedic literature, Samhitas (classical books), modern literature, journals, magazines and online available materials. considered. Review Method: Relevant various data source materials were considered for this. Result: stress will be relieved because this therapy acts directly on hormones secretion which is responsible for relieving stress. Conclusion: By this ther- apy, a patient gets relief without any expenses and the most important is that without using hormonal treatment. Marma therapy in stress can relieve stress by maintaining calmness in the brain, it helps to maintain the brain's proper functioning. By this therapy, not only the stress but stress-related other complications can be treated.
Keywords: Marma therapy, COVID-19, post-covid-19, stress.
Multimodal Fusion of Face and Palm Using Local Color Binary Patterns and Haralick Features
Authors: Patil Vijeeta , Kallur Shanta , Hiremani Vani
Published: December 2021

Face recognizable proof has drawn in numerous scientists because of its novel benefit, for example, non-contact measure for include obtaining. Varieties in brightening, posture and appearance are significant difficulties of face acknowledgment particularly when pictures are taken as dim scale. To mitigate these difficulties partially many exploration works have been completed by considering shading pictures and they have yielded better face acknowledgment rate. A strategy for perceiving face utilizing shading nearby surface highlights is depicted. Test results show that Face ID approaches utilizing shading neighborhood surface highlights astonishingly yield preferred acknowledgment rates over Face acknowledgment approaches utilizing just shading or surface data. Especially, contrasted and grayscale surface highlights, the proposed shading neighborhood surface highlights can give great coordinating with rates to confront pictures taken under extreme varieties in enlightenment and furthermore for low goal face pictures. The other biometric framework utilizes palmprint as quality for the recognizable proof and validation of people. The principal point is to extract Haralick highlights and utilization of probabilistic neural organizations for confirmation utilizing palmprint biometric quality. PolyUdatabase tests are taken from around 200 clients every client's 2 examples are gained. This palm print biometric recognizes the phony (fake) palmprint made of POP (Plaster of paris) and separates among living and non-living dependent on the entropy highlight. Test results portray that the eleven Haralick feature values are acquired in execution stage and productive precision is accomplished.
Habilidades Investigativas en el Pregrado de la Carrera de Sociología
Authors: Prudencio Coreas Lourdes Elizabeth
Published: December 2021

OBJETIVO: describir los resultados del diagnóstico situacional del desarrollo de las habilidades investigativas en los estudiantes de la carrera licenciatura en sociología, de la Facultad Multidisciplinaria Oriental, Universidad de El Salvador. El trabajo es producto de la sistematización empírica-documental, realizada en la fase del diagnóstico del proceso de investigación doctoral. MÉTODO: se realizó una revisión y análisis documental del plan de estudio y los programas del área de metodología de la carrera. Asimismo, se aplicaron tres cuestionarios a profesores especialistas de la disciplina de sociología. RESULTADO: con base en el análisis de los documentos curriculares, se constató que no existe de manera clara y explícita un enfoque de formación y de las habilidades investigativas a formar en el licenciado en sociología. CONCLUSIÓN: atendiendo los resultados del análisis documental y empírico de la fase del diagnóstico se concluye en un sistema de habilidades, que, de acuerdo con la situación real del proceso de formación del futuro profesional, deben desarrollarse como resultado de su formación científica a lo largo de los cinco años de la carrera.
INTANGIBLE HERITAGE TOURISM: THE NEPALESE DIASPORA IN MALAYSIA
Authors:   Universiti Tunku Abdul Rahman, Subaramaniam Kavitha , Roy Swagata Sinha ,   Universiti Tunku Abdul Rahman, Budakoti Devendra Kumar ,   Independent Consultant/Researcher
Published: December 2021

Who are you? Where are you from? How did you end up in Malaysia? These are the common questions that the Nepalese community here in Malaysia has had to respond to many a time. We cannot blame the naïve attitudes that our Malaysians possess but it is a matter of regret that most Malaysians from other ethnic groups are not aware of the Nepalese community here, simply because there has been no exposure to their presence. The intangible heritage of one’s ethnicity and culture play a crucial role in pointing out one’s origin, identity and existence. In the context of tourism, it is essential to sustain this minority group as it may arouse the interest of the Nepalese not only in their motherland but also around the globe. Tourists will be interested to learn about how the Nepali diaspora is able to preserve their unique traditions despite the influence of urbanisation and other culturalisations. The authors would apply the functionalist approach to discuss how the intangible tourism not only benefits the nation’s economy but also functions to prevent the extinction of the Malaysian Nepalese customs. The research questions that are posed for this paper are as follows i) How do the Nepalese Malaysians sustain their intangible heritage? ii) What measures are this minority group taking to safeguard their tradition? and iii) In what way will the preservation be able to benefit the country and themselves? In-depth interviews with 15 informants will be conducted along with consensual audio-recording. Transcriptions of the interviews will analyse the thematic patterns coupled with peer checking to reduce bias for the data to be credible and trustworthy. The outcome of this research will be presented.
INFLUENCING FACTORS OF 7PS ON CONSUMER PURCHASE INTENTION OF HALAL TOURISM IN KANO-NIGERIA
Authors:   Universiti Sains Malaysia, Yahya Sulaiman , Kamalul Ariffin Shaizatulaqma ,   Universiti Sains Malaysia
Published: December 2021

Halal Tourism is a social, cultural and economic phenomenon which entails the movement of people to countries or places outside their usual environment for personal or business/professional purposes in accordance with Islamic injunctions. Nigeria has a Muslim population of more than 100 million which makes it an ideal halal marketplace worth trillions of US dollars. As the halal movement gains traction, the global industry has set its sights on Nigeria’s growing demand for shariah-compliant goods and services. The purpose of this paper is to examine the marketing mix strategy for halal tourism consisting of products, prices, promotions, locations, personal preferences, processes and physical evidence of the intent to partake in halal tourism by consumers in Kano-Nigeria. This research paper observes that Nigeria as a country has the potential to make tourism a main source of income seeing as it has a diverse set of tourist attractions, a large domestic tourism market and a unique cultural heritage capable of enticing foreign tourists. This research paper recommends among other things that the entrenchment of a sound halal tourism development master plan capable of rejuvenating the economy of the country and ensuring sustainable halal tourism development even in the face of the current global economic melt-down due to the COVID-19 pandemic. The paper employs the Desk Study approach as its method for gathering the data to be used in this study. The findings of this research paper will benefit those in tourism-related industries and policymakers. The specific identification of certain elements namely: products, prices, promotions, locations, personal preferences, processes and physical evidence of a consumer’s intention to partake in halal tourism in Kano-Nigeria would help halal tourism service providers to offer attractive packages that meet tourist expectations. This paper has its limits as it is a conceptual approach, and empirical studies are both recommended and needed in the future.
A CONCEPTUAL PAPER OF SPIRITUAL TOURISM MODEL (ISToM)
Authors:   Universiti Malaysia Terengganu, Md Sawari Siti Salwa , Mohamad Zaleha ,   Universiti Malaysia Terengganu, Othman Nor’ain ,   Universiti Teknologi MARA, Ramdzan Ali Amirul Eimer ,   International Islamic University Malaysia
Published: December 2021

Spiritual tourism also known as one type of special interest tourism activity based on the expectations related with spirituality is now continuously developing and is being demanded by tourists. This demand is in line with the improvement of tourist information technology. Spiritual tourism will continuously develop due to the changes in the needs of the market. Initially, spiritual activities are directly connected with religion, and they have now shifted to the idea to something that is related with spiritual activities which include, creating comfort, pleasure and quality experience. Despite of the rapid development, it can be seen in the academic writing research, in which, there are still several researchers who argued religious and spiritual tourism as the same type of tourism. The phenomenon of religious spiritual tourism is more complex in the modern era and has been recognised as a separate tourism. Internationalising religious spiritual tourism in the context of people, places, and events has become a challenge. Religious spiritual tourism requires a new mode as a form of quality tourism development so that it will organise sociocultural life with varieties of unique customs and become a tool to increase regional income, creating job opportunities and indirectly improve Malaysians’ quality of life. Thus, there is an urge to integrate the religious aspect into spiritual tourism. Hence, this research aims to develop an Islamic Spiritual Tourism Model (ISToM) based on Maqasid As Shariah. It is hoped that the findings will contribute to the existing knowledge about values and provide implications for developing spiritual tourism sustainably.
ESSENTIAL OIL ANALYSIS OF THE „MICROMERIA JULIANA“ (L.) BENTH., FROM LUŠTICA, MONTENEGRO
Authors:   Faculty of Sciences and Mathematics, University of Niš, Filipović S. , Radulović N.
Published: December 2021

Micromeria (Bentham, 1829.) is a polymorph genus of Lamiaceae with about 130 species grouped in three sections: Cymularia, Eumicromeria and Pseudomelissa, the most diverse in Mediterranean regions, but widespread across Europe, Asia, Africa, and North America [1]. Up to now, eight Micromeria species have been recorded inhabiting the territory of Montenegro including a dwarf shrub, Micromeria juliana (L.) Benth. Knowing the existence of the variability in quantity and qualitative makeup, interpopulational, and the interspecies variability of the up to now reported essential oils from this plant prompted us to make the detailed analysis of the M. juliana specimens originating from rocky, sunny carbonate rock bases in Zabrđe, Montenegro, since the plant material from this area was not examined before. Detailed GC-MS analysis of the obtained essential oil resulted in 70 identified components among which α-pinene (12.2%), (E)-nerolidol (8.9%), viridiflorol (6.8%), limonene (6.1%), and borneol (5.2%) prevailed, differing significantly in content from the previously reported populations (Morača canyon, Cijevna canyon, Mt. Orjen and Mt. Krivošije) [2]. The objective of this study is to gain insight into the essential oil structure, determine the possible mutual similarity and the variability in their chemical compositions, and to enclose possible diversity in the secondary metabolite profile dependent on the site of collection.
17-SUBSTITUTED STEROIDAL TETRAZOLES – NOVEL LIGANDS FOR HUMAN STEROID-CONVERTING CYP ENZYMES
Authors:   University of Novi Sad,Faculty of Sciences, Jovanović-Šanta Suzana S. , Oklješa Aleksandar M. , Sachanka Antos B. , Dzichenka Yaraslau U. , Usanov Sergei A.
Published: December 2021

In animal and human organisms, there are many enzymes, members of the family of heme- containing proteins, cytochromes P450 (CYPs), included in the biosynthesis and metabolism of many biomolecules, as cholesterol, bile acids, sex, and corticosteroid hormones, as well as in metabolism of drugs and xenobiotics. It is also well-known that different imidazole and triazole derivatives are efficient inhibitors of CYPs activity. In this study, we present in vitro screening of binding of novel androstane derivatives with tetrazole- containing substituents in position 17 to human recombinant steroid-converting CYP enzymes: CYP7A1, CYP7B1, CYP17A1, CYP19, and CYP21. Initial screening was performed using a high throughput screening approach, while the affinity of the ligands was analyzed using spectrophotometric titration. For some among tested compounds type I spectral response (substrate-like binding) for CYP7A1 selectively, while for one compound type II spectral response (inhibitor-like binding) for CYP21 were detected, with micromolar values of Kds. Interestingly, one compound with mixed spectral response was found to bind for CYP7B1, which means that there are two optimal positions of the ligand inside the protein active site. Such results could be useful in CYP-inhibiting drug development, during a fast, high-throughput screening of pharmacological potential of novel compounds, as well as in side- effects recognizing.
PHYTO-MEDIATED SYNTHESIS OF SILVER NANOPARTICLES USING AQUEOUS EXTRACT OF „BUGLOSSOIDES PURPUROCAERULEA“ (BORAGINACEAE) AND THEIR BIOACTIVITY
Authors:   University of Kragujevac, Institute for Information Technologies, Katanić Stanković Jelena S. , Srećković Nikola , Mihailović Vladimir
Published: December 2021

In this study, silver nanoparticles (AgNPs) have been synthesized using the aqueous extract of the aerial parts of B. purpurocaerulea, collected in Serbia. B. purpurocaerulea silver nanoparticles (Bp– AgNPs) synthesis was confirmed using UV-Vis spectroscopy and Fourier Transform Infrared Spectroscopy (FTIR). The biological potential of synthesized Bp-AgNPs was evaluated in vitro using ABTS assay for determining free radical scavenging potential and microdilution method for analysis of antimicrobial properties. Bp-AgNPs showed high antioxidant activity similar to Bp-extract, comparable to BHT. The synthesized nanoparticles exerted remarkable antibacterial effects, with minimal inhibitory concentration (MIC) values below 20 µg/mL. In the case of some bacterial strains, the results of Bp– AgNPs were comparable or similar to standard antibiotic erythromycin. The antifungal activity of Bp– AgNPs was moderate for most of the used strains. Nevertheless, several fungi were resistant to the NPs action, while two tested Penicillium species were extremely sensitive on Bp-AgNPs with MIC lower than 40 µg/mL. The antimicrobial properties of Bp-AgNPs can be useful for the development of new NPs-containing products.
Standard mark table and standard USCI-CF table of the point group D6h. Unification of candidates derived from different D6h-skeletons
Authors:   Shonan Institute of Chemoinformatics and Mathematical Chemistry, Japan, Fujita Shinsaku
Published: December 2021

Combined-permutation representations (CPRs) for characterizing -skeletons (a benzene skeleton, a Haworth-projected skeleton, a superphane skeleton, and a coronene skeleton) are constructed by starting from respective sets of generators, where the permutation of each generator is combined with a mirror-permutation of 2-cycle to treat both achiral and chiral substituents under the GAP system. Thereby, the CPR of degree 8 (= 6 + 2) for the benzene skeleton, the CPR of degree 14 (= 12 + 2) for the Haworth-projected skeleton, the CPR of degree 14 (= 12 + 2) for the superphane skeleton, the CPR of degree 14 (= 12 + 2) for the coronene skeleton are generated to give primary mark tables (tables of marks) based on these CPRs. These primary mark tables generated by the GAP system are different in the sequence of subgroups from each other, although they stem from the same point group . They are unified into a single standard mark table by means of a newly-devised GAP function MarkTableforUSCI. Moreover, another newly-devised GAP function constructUSCITable is employed to construct a standard USCI-CF (unit-subduced-cycle-index-with-chirality-fittingness) table concordantly. After a set of PCI-CFs (partial cycle indices with chirality fittingness) is calculated for each skeleton, symmetry-itemized combinatorial enumeration is conducted by means of the PCI method of Fujita’s USCI approach (S. Fujita, Symmetry and Combinatorial Enumeration in Chemistry, Springer-Verlag, Berlin-Heidelberg, 1991).
Energy of extended bipartite double graphs
Authors:   Karnatak University, Dharwad, India, Ramane Harishchandra S. , Parvathalu B. , Ashoka K.
Published: December 2021

The energy of a graph is the sum of the absolute values of its eigenvalues. In this article, an exact relation between the energy of extended bipartite double graph and the energy of a graph together with some other graph parameters is given. As a consequence, equienergetic, borderenergetic, orderenergetic and non-hyperenergetic extended bipartite double graphs are presented. The obtained results generalize the existing results on equienergetic bipartite graphs.
A graph operation and its applications in generating orderenergetic and equienergetic graphs
Authors:   Government Engineering College, Kerala, India, Joseph Subin P.
Published: December 2021

A general graph operation is defined and some of its applications are given in this paper. The adjacency spectrum of any graph generated by this operation is given. A method for generating integral graphs using this operation is discussed. Corresponding to any given graph, we can generate an infinite sequence of pair of equienergetic non-cospectral graphs using this graph operation. Given an orderenergetic graph, it is shown that we can construct two different sequences of orderenergetic graphs. A condition for generating orderenergetic graphs from non-orderenergetic graphs are also derived. This method of constructing connected orderenergetic graphs solves one of the open problem stated in the paper by Akbari et al.(2020).
Estonia y Singapur: Casos de éxito de la Transformación Digital
Authors: Rios-Campos Carlos , Ynga Enrique Guillermo Llontop , Grado Oscar Esteban García , Mujica Cristian Gladio Valentín , Aguirre Giuliana Fiorella Samame , Zaquinaula Irma Rumela Aguirre , Torres Antero Alexander Cabrera Torres , Vargas Daniel Jesús Castro
Published: December 2021

Resulta necesario comprender lo sucedido en Estonia y Singapur con respecto a la Transformación Digital, considerando que a nivel mundial se presentó un desafío a cualquier tipo de organización con el inicio de la pandemia en el año 2020. Se planteó el objetivo general, analizar a Estonia y Singapur: Casos de éxito de la Transformación Digital. Metodología, la investigación presentó un diseño cualitativo-interpretativo, de tipo documental, se han seleccionado 54 documentos, realizados en el periodo 2016 – 2021, incluyendo: artículos científicos, artículos de revisión e información de sitios web de organizaciones reconocidas. Las palabras claves utilizadas en las búsquedas fueron: Transformación digital, Estonia, Singapur. Resultados, la transformación digital resulta importante y urgente en las organizaciones y países, sobre todo en estos momentos de pandemia. En Estonia y Singapur, destaca la fuerte inversión por parte del estado y el compromiso y adaptación de su sociedad con los cambios de la transformación digital. Conclusiones, Estonia y Singapur son dos casos de éxito de la transformación digital, por ello muchos países buscan su asesoría y establecer convenios. Este proceso de transformación digital, ha requerido un esfuerzo constante y un alto compromiso de los actores del mismo.
A Learning Journey through a Heart-Centered Book
Authors: Allen Wendy , Ryan Lori
Published: December 2021

As faculty for a graduate program in early childhood leadership, we co-designed a course on community-based action research around Patricia Wilson’s book, The Heart of Community Engagement: Practitioner Stories from Across the Globe. In this review we share how it mirrored our own deepening sense of community engagement practices, and how our students engaged with this unique text on their individual and collective learning journeys. We share highlights from the text that reinforced our sense of liberatory pedagogy.  Wilson’s  personal  stories, as well as the stories of community-engaged practitioners across the globe , invite all of us to create our own purpose and intentions for the evolving path of facilitating change within ourselves and with others.
Awareness Based Systems Change and Racial Justice
Authors: Cunningham Dayna
Published: December 2021

In my years working as a racial justice lawyer I came to realize that the law, while an incredibly important part of the work, is too blunt an instrument for the work of opening people’s hearts. What awareness-based systems change, and Theory U in particular, has to offer is a framework and method for doing this subtle work. In this piece I describe the ways in which this approach can serve as a powerful tool in the transformation of systemic and structural violence through its core movement of turning the beam of observation back on self and system with open-mind (curiosity), open-heart (compassion) and open-will (courage). If structural violence is a series of societal agreements to not pay attention to a set of people we deem less human than ourselves, as I believe it is, then what does it mean to cultivate a quality of attention that redresses these agreements? Not averting our eyes from the systemic racism that shapes our collective existence is core, as is witnessing with a tender heart.  Then connecting the tender heart to effective action means acting with understanding of the urgent need to see from the whole, which cannot exclude anyone, especially people who have been marginalized. While you do not unmake centuries of injustice and violence by paying attention with an open-mind, heart, and will, you do help the social body in the room become more effective at the thing they are trying to do - beginning to address centuries of injustice and violence. That is the potential of awareness-based systems change.
Assessment of Performance Appraisal in Visakhapatnam Port Trust (VPT)
Authors:   Research Scholar, Dept. of RMCS, C.C.Sc, PJTSAU, Hyderabad, Soujanya K.
Published: December 2021

Once the employee has been selected, trained and motivated, he is then appraised for his performance. Performance appraisal is the step where the management finds out how effective it has been at hiring and placing employees. Thus, teachers evaluate the performance of students, bankers evaluate the performance of creditors, parents evaluate the behavior of their children and all of us consciously or unconsciously evaluate our own actions from time to time. In social interactions, performance is considered a systematic and planned manner to achieve widespread popularity in recent years. Performance appraisal is essential to understand and improve the employee’s appraisal. It was viewed that performance appraisal was useful to decide upon employee promotion/transfer salary determination and the like. But the recent development in human resources management, it indicates the levels of desired performance levels, of actual performance in gap between this two. This gap should be bridged through human resources development techniques like training, executive development etc., For the main asset is employees according to the employee’s performance the production, sale is happened to the organization according to that the profit and growth of the organization is increased or decreased for that the employee performance is most important. The employee performance is known by performance evaluation only. In other words, performance appraisal can be defined as the systematic evaluation of the individual with respect to their performance on the job and their potential development and his or her judgments, targets achieved by him or her, etc. The study aimed to investigate the assessment of performance appraisal is given to the employees working in the Visakhapatnam port trust.
How to Habits of Drinking Alcohol "SOPI" in Community?- Dental Caries Status
Authors:   Department of Dental Health, Poltekkes Kemenkes Yogyakarta, Yogyakarta, Indonesia, Ayun Quroti
Published: December 2021

Dental and oral health problems in the people of East Nusa Tenggara Province are in the high category. The people of Coal Village have a habit of drinking sopi, a traditional alcoholic beverage. Frequently drinking alcoholic beverages for long duration has a negative risk to the oral health. Sopi is one of the traditional alcoholic beverages, fermented from Enau (palm) tree plants. The purpose of this research is relationship between the habits of drinking sopi and the status of dental caries. Method: This is a research of Analytical Survey. This research was conducted in November to December 2019. The population on this research was the society of sopi drinkers. The total sampling was 76 people. The data collecting of the sopi drinking habits was carried out by completing the checklists; the data of the dental caries status was obtained by direct examinations. The data analysis used the test of Kendall’s Tau c. Results: The duration of drinking sopi was classified in the old category (93,4%); the frequency of drinking sopi was classified in the frequent category (63,2%); the volume of the drunk sopi was classified in the lots category (61,8%); the habits of drinking sopi was classified in the heavy category (93.4%); and the dental caries status was classified in the high criterion (52,6%). Based on the correlation test results, that there was no relationship between the time duration, frequency, volume, and the habits of drinking sopi with the status of dental caries (P < 0,05). Conclusion: There was no relationship between the habits of drinking sopi and the status of dental caries.