bluuebunny/crossref_metadata_2025 huggingface dataset:
Appraisal of long-term rainfall trends and rainfall erosivity in diverse agroclimatic zones of Chhattisgarh state, India: Implication for soil and water conservation measures
Authors: Dash Ch. Jyotiprava , Yadav Prachi , Kumar Randhir , Patra Sitanshu Sekhar , Hombegowda H.C. , Adhikary Partha Pratim
Published: November 2023

This study delved into the trends of rainfall and rainfall erosivity (R-factor) over a span of 120 years (1901–2020) using monthly precipitation data from 16 stations in Chhattisgarh state, India. Various statistical methods including homogeneity tests, non-parametric trend tests, and Sen's slope estimator were employed to discern the trends and slope values. The results, at a 5% significance level, underscored a significant increasing trend in rainfall for the Bastar plateau, while the Chhattisgarh plains, Northern hills, and Chhattisgarh state exhibited a declining trend in annual rainfall. However, no specific trend was observed in pre- and post-monsoon seasons. During the winter season, the Bastar plateau, Northern hills, and Chhattisgarh state experienced declining rainfall, whereas the Chhattisgarh plains showed no discernible trend. Notably, the Northern hills exhibited the highest mean annual R-factor (12519.4 MJ mm ha-1 h-1 year-1), followed by the Chhattisgarh plains (11587.7 MJ mm ha-1 h-1 year-1) and the Bastar plateau (9633.5 MJ mm ha-1 h-1 year-1). On the broader scale, the annual R-factor trend for Chhattisgarh state indicated a decline, estimated at a rate of 0.74 MJ mm ha-1 h-1 year-1. This decline was attributed to a reduction in overall rainfall, although it's important to note that this decrease in R-factor doesn't necessarily signify a decline in soil erosion or soil health deterioration. To adapt to the varying rainfall patterns, it's imperative to implement region-specific measures that can effectively address both increasing and decreasing trends in rainfall. This targeted approach is crucial for sustainable management of soil erosion and preservation of soil health in the study area.
Classification and Identification of Tea Diseases Based on Improved YOLO V7 Model of MobileNeXt
Authors: Xia Yuxin , Yuan Wenxia , Zhang Shihao , Wang Qiaomei , Liu Xiaohui , Wang Houqiao , Wu Yamin , Yang Chunhua , Xu JiaYi , Li Lei , He Junjie , Cao Zhiyong , Wang Zejun , Zhao Zihua , Wang Baijuan
Published: November 2023

To overcome the constraints associated with conventional approaches used in the classification and detection of tea diseases, which are characterized by their limited accuracy and sluggish responsiveness, this study introduces an enhanced YOLOv7 lightweight model algorithm integrated with MobileNeXt. This refinement not only bolsters the model's capacity for extracting and processing features but also effectively lightens the computational load, expedites recognition, and integrates a dual-layer routing attention mechanism visual converter to enhance the capture of crucial details and textures within disease images. Consequently, these enhancements lead to improved model performance and computational efficiency, ensuring precise and rapid identification of tea diseases. Furthermore, this model incorporates the more appropriate SIoU as the loss function, mitigating losses, minimizing omissions, and reducing misclassifications, thus resulting in superior recognition, even in complex image backgrounds. Based on the training outcomes, the enhanced model attains Precision, Recall and mean Average Precision scores of 93.5%, 89.9%, and 92.1%, respectively, marking substantial enhancements of 5.06%, 2.16%, and 2.91% compared to the original YOLOv7 model. Additionally, the model's size is reduced by 19.12%, and its detection speed accelerates by 11.13%. This improved model excels in accurately and expediting.
A novel phage endolysin inactivates a wide range of Staphylococcus aureus and eliminates mono- and mixed-species biofilms associated with S. aureus
Authors: Rao Xiancai , Liu He , Wei Xuemei , Wang Zhefen , Huang Xiaonan , Li Mengyang , Hu Zhen , Zhang Kexin , Hu Qiwen , Peng Huagang , Shang Weilong , Yang Yi , Wang Yuting , Lu Shuguang
Published: November 2023

Staphylococcus aureus and its single or mixed biofilm infections seriously threaten global public health. Phage therapy, which uses active particles or phage-derived endolysins, has emerged as a promising alternative strategy to antibiotic treatment. However, high-efficient phage therapeutic regimens have yet to be established. In this study, we used a mixed-sample procedure to isolate phages against methicillin-resistant S. aureus (MRSA) XN108. We characterized a new phage, SYL, sequenced its genomes, and engineered its novel endolysin, LysSYL. LysSYL demonstrated stability under various conditions and exhibited a broader range of efficacy against staphylococcal strains than its parent phage (100% vs. 41.7%). Moreover, dynamic live/dead bacterial observation demonstrated that LysSYL could completely inactivate MRSA USA300 within 10 min. Scan and transmission electron microscopy revealed evident bacterial cell perforation and deformation. In addition, LysSYL displayed strong eradication activity against single- and mixed-species biofilms associated with S. aureus. It also had the ability to disrupt bacterial persisters, and it proved highly effective in eliminating persistent S. aureus when combined with vancomycin. Furthermore, LysSYL protected BALB/c mice from lethal S. aureus infections. A single-dose treatment with 50 mg/kg of LysSYL resulted in a dramatic reduction in bacterial loads in the blood, liver, spleen, lungs, and kidneys of a peritonitis mouse model, which resulted in rescuing 100% of mice challenged with 108 colony forming units of S. aureus USA300. Overall, the data provided in this study highlight the strong therapeutic potential of endolysin LysSYL in combating staphylococcal infections, including mono- and mixed-species biofilms related to S. aureus.
The role of the Trigeminocardiac Reflex in a Traumatic Brain Injury Death: Case Report
Authors: Radanović Dražen , Mirčić Uroš , Radnić Bojana , Elboursh Dušan , Bogosavljević Đurđina , Stanisavljević Jovana , Antonijević Jovana , Knežević Saša , Čukić Bojan , Pajić Srbislav
Published: November 2023

The trigeminocardiac reflex (TCR) is defined as sudden onset of parasympathetic dysrhythmias including hemodynamic irregularities, apnea, and gastric hypermotility during stimulation of sensory branches of the trigeminal nerve. Back in 1999 when TCR was first described as such, a clinical discussion on the establishment of terminology is ongoing. We present a case of a 31-year-old male patient who was admitted to the Emergency Department due to traumatic brain injury who died with clinical manifestations of TCR. TCR can be a red flag for neurosurgeons when treating patients with traumatic brain injury.
Association of serum albumin and left ventricular ejection fraction on all-cause mortality of patients with stable coronary artery disease
Authors: Zhang Hua , Qiu Shaodong , Chen Fei , Wang Xiaojun
Published: November 2023

Objective: To explore serum albumin (Alb) and left ventricular ejection fraction (LVEF) in predicting all-cause mortality (ACD) in patients with stable coronary artery disease (SCAD).
Method: Patients with SCAD were divided into 4 groups according to their Alb and LVEF levels. The KM curves were used to compare ACD among the four groups. ROC curves were used to compare the efficacy of predicting ACD among the combination of Alb and LVEF and either Alb or LVEF alone. Cox regression analysis identified the influencing factors of ACD in patients with SCAD and detected the correlation between Alb and LVEF.
Results: ACD occurred in 18 (8.9%) of 203 patients with SCAD, with an average follow-up of 26.53±14.34 months. In the K‒M analysis, the risk of ACD in the four groups ranged from high to low: Group A (26.7%)>Group B (17.6%)> Group D (0.9%) > Group C (0%, P<0.001). The ROC curve showed that the combination of Alb and LVEF (AUC=0.888) had better predictive value for ACD than either Alb (AUC=0.879) or LVEF alone (AUC=0.651), P<0.001. Multivariate Cox regression analysis showed that Alb ≤4 g/dL predicted ACD events after adjusting for baseline (HR: 12.16, 95% CI: 1.57 to 94.41; P =0.017) and treatment (HR: 19.36, 95% CI: 2.53-147.78, P =0.004). Alb was positively correlated with LVEF (r=0.22, P=0.002).
Conclusions: Alb combined with LVEF is more effective than a single index in predicting ACD in SCAD and could be used as a new model to judge the prognosis of SCAD.
CRISPR/Cas9-based genome-wide screening for Metastasis ability identifies FCGR1A regulating the metastatic process of ovarian cancer by targeting LSP1
Authors: Jiang Hui , Qi Yingying , Zhang Ting , Zhu Weiyan
Published: November 2023

Background: Metastasis is a main cause of death from ovarian cancer(OC). Screening key makers involved in OC metastasis can help to effectively detect early metastasis postoperatively. However, the role of FCGR1A involved in OC metastasis has yet to be fully established.
Methods: A genome-wide CRISPR/Cas9-based screening system was used to identify regulatory factor in metastasis. Expression of FCGR1A and LSP1 in the ovarian cancer cell lines was examined by quantitative real-time polymerase chain reaction (qRT-PCR).The functions of FCGR1A and LSP1 in OC cell migration, invasion and proliferation were determined using wound healing assay, transwell invasion assay and CKK8 assay. A transcription-activated library was used to identify the potential downstream gene of FCGR1A. FCGR1A expression was immunohistochemically detected and IRS scores were calculated.
Results: FCGR1A was upregulated in OC cells compared with normal ovarian cell. Downregulation of FCGR1A inhibited the metastasis, proliferation and EMT progression in OC cells in vitro and intraperitoneal metastasis in vivo.Moreover, Downregulation of FCGR1A accompanied with lower LSP1 expression. Overexpression of LSP1 partially reversed the tumor suppressive function caused by FCGR1A Downregulation. The higher FCGR1A expression level was related to metastasis, higher grade, higher stage, and lymph node metastasis of OC. Survival analysis suggested that the group with higher FCGR1A expression had a lower tumor-free survival rate and a lower overall survival rate than the group with low FCGR1A expression.
Conclusion: FCGR1Aenhances OC metastasis by regulating LSP1 and that FCGR1A is associated with poor prognosis, supporting FCGR1A as a potential predictive factor for detecting early metastasis postoperatively.
Tomato Leaf Disease Detection Using Convolutional Neural Network
Authors: Parvez Shamima , Uddin Md Ashraf , Islam Md Manowarul , Bharman Pallab , Talukder Md. Alamin
Published: November 2023

Leaf diseases pose a significant threat to crop production and profitability, particularly in the case of tomatoes, which are extensively cultivated worldwide. Early detection of these diseases is crucial to prevent significant crop losses. In this study, we propose a novel deep learning-based approach for disease detection and prediction in tomato plant leaves. Convolutional neural networks (CNNs) have emerged as the most effective deep learning algorithm for image classification tasks. Leveraging the power of CNNs, we employed a CNN architecture to detect and identify diseases in tomato leaf samples. The suitability of CNNs for detection and prediction tasks makes them an ideal choice for this study. Our dataset comprised 6,926 images of both healthy and diseased tomato plants obtained from the PlantVillage dataset. By training our CNN model on this dataset, we achieved a promising test accuracy of 98.39\%. This high accuracy demonstrates the effectiveness of our approach in accurately predicting the presence of diseases in tomato plant leaves. Through our study, we aim to contribute to the early detection and prevention of leaf diseases in tomato plants, ultimately improving crop productivity and ensuring the profitability of tomato cultivation.
Consequences of polypharmacy among the people living with dementia: a systematic review and meta-analysis
Authors: Talukdar Imdadul Haque , Saha Sanjib
Published: November 2023

Background
The objective of this systematic review and meta-analysis was to synthesise and summarise studies on the consequences of polypharmacy on people living with dementia (PwD), categorize the consequences, analyse the quality of the studies, and estimate pooled effect sizes of these consequences.
Methods
A systematic literature review was conducted following the PRISMA guideline. Covidence software was used for screening, study selection and data extraction. The quality of the selected studies was assessed using an adapted version of Newcastle-Ottawa Scale (NOS) scale. Random effect models were used to perform the meta-analyses and the heterogeneity among the studies was assessed by i2 statistics.
Results
Nineteen studies were selected for this review. The four most frequent consequences were: potentially inappropriate medication (PIM) (n = 6, 31.6%), hospitalisation (n = 4, 21%), adverse drug reaction (ADR) (n = 3, 15.8%), and mortality (n = 3, 15.8%), all of which were significantly associated with polypharmacy. The quality of the reviewed studies was fair to good quality (good, n = 13 and fair, n = 6). Meta-analysis was performed with five studies related to PIM and revealed that the odds of having PIM among the PwD exposed to polypharmacy was 2.93 times (95% CI: 2.24–3.82; I2 = 95.6%). Heterogeneity was observed in the selected studies with regards to study design, sample size, follow-up duration, adjustment of confounders, as well as definitions of polypharmacy and inconsistent tools for dementia diagnosis.
Conclusions
Polypharmacy is associated with PIM use, ADR, mortality and hospitalisation for PwD despite high heterogeneity among the studies in terms of polypharmacy definition and dementia diagnosis.
Prospero Registration Number: CRD42023404749
Sustainability of the Higher Educational Institute : a Systematic Literature Review and Future Research Directions
Authors: ghosh pravash
Published: November 2023

This paper critically synthesizes the present literature on sustainable institute over the past 9 years to explore the various constructs associated with it using the Antecedents, Decisions and Outcomes (ADO) model. It also determines both the research gaps and the future research directions. A systematic literature review process (SLR) as proposed by (Tranfield, Denyer, and Smart 2003) is followed. Applying the PRISMA framework, 84 full-text articles relevant to the sustainable institute (in business management) were extracted. This systematic review synthesizes the antecedents, decision processes and consequences of sustainable institute in the business management domain. This review illustrates the information of the most prominent authors, journals and countries. The most important contribution of this study is that it proposes a framework that explain the theoretical underpinning of sustainable institute. It also provides insights into how faculty level, student level, institute level and other factors influence sustainable institute. The study also identifies the major factors that lead to a sustainable institute and helps for the sustainable development of the institute in a holistic manner.
Biocontrol potential and mechanism of action of Bacillus tequilensis JK-11 against Bipolaris sorokiniana.
Authors: kang kun , Fan Junmin , Zhang Haotian , Chen Lulu , Lei yang , hu yuansen
Published: November 2023

Root rot of wheat, caused by the pathogen Bipolaris sorokiniana, has emerged as a major concern for wheat yield damage and food security in central China. Given their environmentally friendly nature, biological control methods are becoming increasingly popular. We conducted a study to assess the antagonistic effect of Bacillus tequilensis JK-11 on B. sorokiniana. Spore germination and mycelial dry weight of B. sorokiniana decreased by 84.9% and 80.63% after JK-11 culture filtrate treatment with a concentration of 20%. SEM observed significant damage to the microscopic morphology of B. sorokiniana cells, and LSCM observed significant apoptosis of B. sorokiniana mycelial cells in the treated group, in addition to changes in ergosterol and electrical conductivity suggesting elevated mycelial cell membrane permeability. In contrast to the untreated group, CF-treated B. sorokiniana cells showed significant DNA and mitochondrial damage and excessive accumulation of reactive oxygen species. The activities of antioxidant enzymes and key enzymes involved in metabolic processes were significantly impaired in mycelial cells treated with different concentrations of CF. Wheat potting experiments using JK-11 revealed its ability to stabilize wheat root colonization for a certain period. Moreover, the bacterial suspension of JK-11 had a significant impact on wheat root rot prevention post-irrigation. The study results suggest that JK-11 strain of B. tequilensis exhibits great potential for controlling wheat root rot and offers a fresh approach to wheat management.
Elevated CD56brightNK cell and IFNγ levels in the blood of children with common cold provides a clue for preventing COVID-19
Authors: Chen Zhanpeng , Chen Zhanpeng , Chen Zhanpeng , Chen Zhanpeng
Published: November 2023

Objective: We aim to detect and compare the levels of natural killer (NK) cells (CD56bright and CD56dim), interleukin (IL)18, interferon (IFN)α, and IFNγ in the blood of children with common colds and healthy children, in order to provide clues for the prevention of coronavirus disease 2019（COVID-19）at the current stage.
Study design: A total of 153 children, including 49 with common colds and 104 healthy children, were recruited for this cross-sectional study. The demographic characteristics and lifestyle habits of healthy children and children with common cold are similar. Peripheral venous blood samples were collected by professional nurses for flow cytometry analysis and cytokine determination.
Results: We found that compared to healthy children, children with common colds had significantly reduced forced vital capacity (FVC), and increased CD56brightNK cell ratio, and levels of serum IL18 and IFNγ (all P < 0.05). Linear regression analysis showed that the increase in IFNγ level was positively correlated with the increase in CD56brightNK cell, IFNα, and IL18 levels (all P < 0.05). The increase in CD56brightNK cell ratio was positively correlated with the increase in IFNγ and IL18 levels (all P < 0.05).
Conclusions: Children may resist common cold by increasing the levels of CD56brightNK cells, IFNγ, and IL18 in their blood, which could be the reason why children are more susceptible to common cold but exhibit stronger immunity against COVID-19. CD56brightNK cells may serve as a crucial breakthrough in addressing the current prevalence and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.
Feasibility of clinical target volume (CTV) automatic delineation using deep learning network for cervical cancer radiotherapy: a study with external validation
Authors: Wu Zhe , Liu Mujun , Pang Ya , Huyan Ruoxi , Wang Dong , Xu Cheng , Yang Yi , Peng Shengxian , Deng Lihua , Wu Yi
Published: November 2023

Purpose To explore the accuracy and feasibility of a proposed deep learning (DL) algorithm for clinical target volume (CTV) delineation in cervical cancer radiotherapy and evaluate whether it can perform well to external cervical cancer and endometrial cancer cases for generalization validation. Materials and methods A total of 332 patients were enrolled in this study. A state-of-the-art network called AttResCNet, which adopted Resnet50 based on a channel and spatial attention as backbone was proposed. 236 cervical cancer cases were randomly grouped into training (n = 189) and internal validation (n = 47) cohorts. External validations were performed in a separate cohort of 54 cervical cancer and 42 endometrial cancer cases. The performances of the proposed network were evaluated by dice similarity coefficient (DSC), sensitivity (SEN), positive predictive value (PPV), 95% Hausdorff distance (95HD) and oncologist clinical score when comparing them with manual delineation in validation cohorts. Results In internal validation cohorts, the DSC, SEN, PPV, 95HD for AttResCNet achieved 0.775, 0.796, 0.740, 10.156 mm. In external independent validation cohorts, AttResCNet achieved 0.765, 0.805, 0.729, 12.075 mm for cervical cancer cases and 0.766, 0.803, 0.738, 11.527 mm for endometrial cancer cases, respectively. The clinical assessment score showed that minor and no revisions (delineation time was shortened to within 30 minutes) accounted for about 85% of all cases in DL-aided automatic delineation. Conclusions We demonstrated the problem of model generalizability for DL-based automatic delineation. The proposed network can improve the performance at automatic delineation for cervical cancer and shorten manual delineation time at no expense of quality. The network showed excellent clinical viability, which can also be even generalized for endometrial cancer with excellent performance.
Deploying Support Vector Machines and Rule-Based Algorithms for Enhanced User Training in Cloud ERP: A Natural Language Processing Approach
Authors: Shibghatullah Assoc. Prof. Dr. Abdul Samad Bin , Ling Assoc. Prof. Dr. Chloe Thong Chee , Sarsam Assistant Professor Dr. Samer Munthana , Cherukuri Prof. Dr. Aswani Kumar , Qazi Professor Dr. Saad Ahmed , Hong Koh Chee
Published: November 2023

The authors have requested that this preprint be removed from Research Square.
Modelling the Cloud Computing Adoption Market Scenarios Using System Dynamics
Authors: Pandey Abhinav , Swami Sanjeev , Bhusan Sanjay
Published: November 2023

Cloud computing adoption market scenarios have been modelled using stock-and-flow concept of systems dynamics. The stock variables have been defined as Potential Adopters, Early Adopters and Late Adopters principally based on Bass Model. The flow variables have been defined as rate of early adoption, rate of industry adoption and rate of future adoption respectively in cloud adoption scenarios as simulated through modelling. Auxiliary variables which impact the rate of cloud adoption are factors identified through expert opinion which will impact the adoption of cloud computing in business organizations. Cloud service providers needs to trade the Product-Market expansion path, as single product and/or single market will eventually saturate over a period of time, when all potential adopters will adopt cloud computing and hence the adoption rate of cloud offerings will saturate with a S- curve.
Investigating Differentiated Instruction and the Contributing Factors to Cater EFL Students’ Needs at the Collegial Level
Authors: Tajik Omid , Noor Shagofah , Golzar Jawad
Published: November 2023

Teaching language has its challenges for many reasons, including learners’ background, learning styles, motivation, and socioeconomic status. However, EFL students can benefit from differentiation across the learning continuum to a large extent. This study aimed to investigate Afghan EFL learners’ perceptions of differentiated instruction and the factors that contributed to cater their needs. This study revolved around five main elements of differentiated instruction: learning environment, content, process, product, and assessment. In this mixed-method research study, a questionnaire was developed and distributed to 102 EFL students at Herat University, Afghanistan, to record their perception of differentiated instruction in their classes. Moreover, three teachers of the English department at the same university were also interviewed to understand their experience implementing differentiated instruction and identify their tensions. The study's results suggested that it is practical to implement differentiated instruction in mixed-level, large heterogeneous classrooms.
Towards Quantifying the Communication Aspect of Resilience in Disaster-Prone Communities
Authors: Okeukwu-Ogbonnaya Adaeze , Amariucai George , Natarajan Balasubramaniam , Kim Hyung Jin
Published: November 2023

In this study, we investigate the communication networks of urban, suburban, and rural communities from three US Midwest counties through a stochastic model that simulates the diffusion of information over time in disaster and in normal situations. To understand information diffusion in communities, we investigate the interplay of information that individuals get from online social networks, local news, government sources, mainstream media, and print media. We utilize survey data collected from target communities and create graphs of each community to quantify node-to-node and source-to-node interactions, as well as trust patterns. Monte Carlo simulation results show the average time it takes for information to propagate to 90% of the population for each community. We conclude that rural, suburban, and urban communities have different inherent properties promoting the varied flow of information. Also, information sources affect information spread differently, causing degradation of information speed if any source becomes unavailable. Finally, we provide insights on the optimal investments to improve disaster communication based on community features and contexts.
Subjective emotional experience mediates cross-cultural differences in emotion perception
Authors: Li Ranran , Briers Torunn , McDonald Skye
Published: November 2023

Understanding the cross-cultural differences in emotion perception has captured the interest of researchers for decades. While various mechanisms have emerged to explain such differences, the general inclination to differentiate emotions, irrespective of whether they relate to others or oneself, has remained unclear. To investigate this overarching propensity, we selected the Toronto Alexithymia Scale (TAS-20) as a suitable instrument for measuring the extent to which individuals typically recognize and describe their own emotional experience. Here we examined the mediating role of self-emotional experience in the context of cross-cultural differences in emotion perception. To make the test more representative of real-life situations, we employed an emotion perception task that simulates naturalistic and complex emotional scenarios. The findings revealed that Caucasian Australian students scored higher than Asian Australian students in the emotion perception task and were more inclined to report subjective emotional experience. Notably, the differences in emotion perception between the two cultural groups were fully accounted for by scores on the TAS-20. This suggests that these distinctions were linked to the general tendency to differentiate between subjective emotions, rather than stimulus-related factors, such as the ethnicity of actors or actresses. Furthermore, we examined whether the propensity of distinguishing between emotion concepts could provide insight into the cross-cultural differences in this general emotion perception tendency. However, no significant correlations were found between conceptual differentiation and either TAS-20 or emotion perception. These null results underscore the importance of contextual settings in emotion studies.
Occupational Stress, Strain, and coping among nursing personnel: A hospital-based cross-sectional study
Authors: Kowshik Shamili , HN Dhanpal , shil Rahul
Published: November 2023

Background
Nurses are the backbone of the healthcare system and the largest healthcare force in the world. They work in multidisciplinary areas in hospitals, nursing homes, government and private sectors, and research and development, which makes them the most stressful personnel in clinical areas.
Objectives
This paper aims to explore occupational stress, strain, and coping among nurses working in a hospital in Bengaluru.
Methodology:
A nonexperimental hospital-based cross-sectional study was conducted from November 2, 2022, to December 2, 2022, using a purposive sampling technique. A total of 77 nurses from different areas participated in the study. Data was collected by the researcher himself through the revised version of the Occupational Stress Inventory (OSI-R) scale. Descriptive statistics were used with the mean, standard deviation, frequency, and percentage. To check the association, chi-square analysis was used.
Results
The research shows that the majority of the nurses had maladaptive stress in terms of role insufficiency (RI), role ambiguity (RA), role boundary (RB), and physical environment (PE). It was observed that there was a high level of vocational strain (VS) and interpersonal strain (IS) with an average social support system (SS) among nurses. A significant association was found between gender and ORQ factors like physical environment, designation of the nurse and ORQ in the area of responsibility, and physical environment of the working area. The PSQ factor, vocational strain was significantly associated with gender. Furthermore, a significant association was also found between gender and PRQ factors like self-care coping and social support (SS) coping skills.
Conclusion
Our data suggested a moderate to high level of occupational stress with less social support among nurses. Consequently, it is imperative for healthcare organizations to acknowledge the existence of occupational stress and collaborate towards devising a resolution, enabling nurses to provide patients with optimal care.
Host transcriptome profiling reveals the IL1RAP as a potential candidate gene for the resistance against Lumpy Skin Disease
Authors: Banabazi Mohammad Hossein , Borm Steven Van , Klingström Tomas , Niazi Adnan , De Clercq Kris , Mostin Laurent , Haegeman Andy , De Koning Dirk-Jan
Published: November 2023

To better understand the mechanisms underlying the response diversity to Lumpy Skin Disease Virus (LSDV), we studied differentially expressed genes (DEGs) between two recovered versus three non-recovered Holstein bulls before the infection challenge and three time points after that. The host transcriptome profiling revealed that IL1RAP gene expression could be a potential determinant in distinguishing between resilient and susceptible cattle (padj < 0.05). It was significantly shifted from up-regulated prior to infection to down-regulated three days post-infection in the LSD-resilient cattle. Its expression remained up-regulated among the susceptible cattle post-infection compared to pre-infection. The results showed that seven days post-infection may be a critical time point for LSD infection. The Gene Ontology (GO) and KEGG pathway enrichment test showed a few enriched GO terms and pathways relevant to the LSD and the involvement of the IL1RAP gene. This pilot study, with limited statistical power, is the first to investigate bovine gene expression profiling in response to LSDV and needs a larger independent trial to confirm the findings.
ANALISIS PENGARUH LINGKUNGAN KERJA DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN DI BMT NUANSA UMAT JATIM PAMEKASAN
Authors: Mubarak Reza , Maulana Asep , Faruq Umarul
Published: November 2023

The Islamic Economic System prohibits usury (riba) and the unfair accumulation of wealth by specific parties. In practical terms, there is a need for widespread dissemination regarding various products, services, the fundamental principles of the relationship between financial institutions and customers, and the permissible ways of conducting business in Islamic finance. Employee performance and productivity are crucial factors for the success of financial institutions. Proper and effective human resource management can enhance employee performance and enable the achievement of company goals. This research aims to determine the influence of the work environment and work motivation on employee performance at BMT NU Jatim in the Pamekasan Regency. The research methodology employs a quantitative approach with a population of 58 individuals, and a saturated sampling technique is used to select the sample. The primary data used in this study are collected through questionnaires. The data analysis technique employed is multiple linear regression analysis. The analysis results indicate that the work environment has a positive and significant impact on employee performance, as does work motivation.
Satisfaction with School Life: Capturing Malaysian Pupils’ Voice from a Multiethnic Perspective
Authors:   School of Educational Studies, Universiti Sains Malaysia, Pulau Pinang, Malaysia, Namoco Sarah , Thien Lei Mee ,   School of Educational Studies, Universiti Sains Malaysia, Pulau Pinang, Malaysia, Kho Siaw Hui ,   School of Educational Studies, Universiti Sains Malaysia, Pulau Pinang, Malaysia
Published: November 2023

This qualitative study aimed at gaining an in-depth understanding of the aspects that shaped pupils’ satisfaction with school life in a multiethnic Malaysian context. The multiple case study design was employed to understand and elicit pupils’ experiences, feelings, beliefs, thoughts and perceptions of their satisfaction with school life in three different types of Malaysian primary schools, namely national primary school (Malay-dominated), national type Chinese primary school (Chinese-dominated) and national type Tamil primary school (Indian-dominated). A total of 18 pupils with six members from each type of Malaysian primary school participated in three focus group discussions. Four themes emerged from the thematic analysis of the interview data: (1) emotional contentment; (2) curricular achievement and co-curricular achievements; (3) safe, conducive and comfortable learning environment; and (4) development of 21st-century skills. These emerging four themes from the participants’ views and experiences provided a holistic perspective on satisfaction with school life in Malaysian primary schools. Practical implications that could be beneficial in leveraging life satisfying experiences of the pupils in the school were discussed. This study has contributed to the body of knowledge with regard to satisfaction with school life from a multiethnic perspective.
Into IR4.0: Charting the Social and Occupational Changes in Industrialised Malaysia
Authors:   School of Distance Education, Universiti Sains Malaysia, Pulau Pinang, Malaysia, Yap Chee Yeong , Chua Hang Kuen ,   School of Distance Education, Universiti Sains Malaysia, Pulau Pinang, Malaysia, Chin Yee Whah ,   School of Social Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia
Published: November 2023

The COVID-19 pandemic may have disrupted the socioeconomic fabrics of the world, but it also has spurred the incorporation of the Fourth Industrial Revolution (IR4.0) technologies into organisational operations, work settings, service deliveries and our everyday life. The workability and cost-effectiveness of these technologies will motivate companies to enhance their incorporation into respective organisational and operational designs. This will subsequently change our employment and the way we work as evident in the technological changes throughout previous industrial revolutions. This overview aims at charting out the universal societal changes, particularly changes in work aspects, corresponding to industrialisation; and how IR4.0 may alter current social and occupational landscapes in the near future. These universals are then used to contextualise the social and occupational changes during Malaysian industrialisation. The challenges and some suggestions for the direction of future research on work/ occupation as Malaysia ventures into IR4.0 are presented at the end of this overview.
Get the Jab: Government Multisemiotic Legitimation of COVID-19 Vaccines in Malaysia
Authors:   School of Humanities, Universiti Sains Malaysia, Pulau Pinang, Malaysia, Rajandran Kumaran
Published: November 2023

The present article studies how the government of Malaysia legitimises COVID-19 vaccines. Vaccination is a whole government endeavour but the Special Committee on COVID-19 Vaccine Supply (Jawatankuasa Khas Jaminan Akses Vaksin COVID-19 [JKJAV]) is the central government organisation that manages national-level vaccination. The management involves a discursive aspect and the discourse on social media sites should be explored because it frames beliefs and practices about vaccines. A qualitative analysis of legitimating strategies and their language and image features were conducted on Malay language posts on Facebook, Instagram and Twitter from February 2021 to July 2021. The posts discursively legitimise COVID-19 vaccines in terms of their characteristics and benefits. The multisemiotic legitimation is achieved by mixing rationalisation, moralisation and authorisation. JKJAV proposes that vaccines are the best means of protection, encouraged by various sources. Cumulatively, the vaccine favourable discourse makes vaccination an exercise of personal choice by an individual. The agency is justified by rational, moral and authoritative reasons, to recreate social dynamics before the pandemic.
Disembodied Surreal Tendencies of Silent Hill the Film: Traces of Japanese Abreaction Terror
Authors: Jaka Pratama Andreas
Published: November 2023

The Silent Hill live action cinema was an adaptation of a survival horror videogame title that explored the theme of loss, delusion, but also of internal conflict that leads to the ultimate self-redemption. Through the psychoanalytical reading, the surreal tendencies and symbolisms are analysed, the signs of abreaction terror sourced historically from the post-war Japan made manifest. This article looks at the possible point of origin of the surreal symbolism utilized by first the videogame iterations, then secondly the adaptation to the silver screen which may not translate into its contextually accurate adaptation. Exposing the roots of such subconscious historical trauma realizes how much the live action films made disembodiment of that spirit resulting in its failure to reach down deeper into the source material.
A recusa da “falácia naturalista” como uma das bases epistemológicas da teoria pura do direito
Authors: Santos Neto Arnaldo Bastos , Lorencini Bruno César , Afonso Túlio Augusto Tayano
Published: November 2023

A falácia naturalista, conforme descrita nas obras de David Hume e George Moore, ocorre quando da conexão de uma cópula proposicional da ordem do ser, como é e não é, para uma proposição na ordem do dever ser, como deve e não deve. Ou seja, existe uma classe de afirmações de fato logicamente distinta de uma classe de afirmações de valor. Neste artigo analisamos como a recusa da falácia naturalista constitui uma das ferramentas conceituais mais importantes da obra kelseniana, presente desde o trabalho que inaugura o projeto da Teoria Pura do Direito, a obra “Os problemas capitais da teoria jurídica do Estado” até a edição póstuma do “Teoria Geral das Normas”, quando Kelsen alude explicitamente sobre a contribuição de David Hume para o seu sistema conceitual normativista.
A methodology for integrating time-lagged rainfall and river flow data into machine learning models to improve prediction of quality parameters of raw water supplying a treatment plant
Authors: Ortiz-Lopez Christian , Torres Andres , Bouchard Christian , Rodriguez Manuel
Published: November 2023

Rainfall and increased river flow can deteriorate raw water (RW) quality parameters such as turbidity and UV absorbance at 254 nm. This study aims to develop a methodology for integrating both time-lagged watershed rainfall and river flow data into machine learning models of the quality of RW supplying a drinking water treatment plant (DWTP). Spearman's rank non-parametric cross-correlation analyses were performed using both river flow and rain in the watershed and RW data from the water intake. Then, RW turbidity and RW UV254 were modelled, using a support vector regression (SVR) and an artificial neural network (ANN) under several prediction scenarios with time-lagged variables. River flow presented a very strong correlation with RW quality, whereas rainfall showed a moderate correlation. Time lags with maximum correlations between flow data and turbidity were a few hours, while for UV254, they were between 2 and 4 days, demonstrating varied time lags and a complex behaviour. The best performing scenario was the one that used time-lagged watershed rainfall and river flow as input data. The ANN performed better for both turbidity and UV254 than SVR. Results from this study suggest the possibility for new modelling strategies and more accurate chemical dosing for the removal of key contaminants.
A Critical Assessment of Remdesivir
Authors: Chandra Subhash , Choudhary Alka N. , Palai Santwana , Rauf Abdur , Aboul-Enein Hassan Y.
Published: November 2023

The COVID-19 pandemic that originated in Wuhan city, China, has affected every village
in India. This has killed millions of people. This disease involves symptomatic and asymptomatic
mutations. The purpose of this review was to assess the effectiveness of remdesivir particularly
against SAR-CoV-2 (Coronaviridae family). The relevant works have been studied with respect to
the drug's chemistry, mechanism of action, pharmacokinetics, pharmacodynamics, clinical data, and
side effects. Remdesivir has been used in many cases of coronavirus-infected patients because it has
been proven to possess beneficial effects; however, significant adverse effects have also been reported.
Remdesivir has been reported to help in lowering the disease's high fatality rate. However,
the WHO has warned against using the medicine because there is no clinical data to support its therapeutic
efficacy.
Validity and Reliability Study in Turkish COVID-19 Literacy Scale
Authors: Türkoğlu Nihan , Kavuran Esin
Published: November 2023

Background:

It is critical to conduct studies on the evaluation of COVID-19 health literacy in different cultures. Health literacy can make it easier to distinguish between reliable information about COVID-19 and misinformation, empowering individuals to make illuminated health decisions and to practice healthy and protective behaviours.

Objective:

The aim of this study is to verify the validity and reliability of COVID-19 Health Literacy Scale (COVID-19-HLS) for Turkish.

Methods:

This was a cross-sectional-descriptive study. The sample was randomly divided into two groups for factor analysis. A total of 712 individuals were included for exploratory (n=350) and confirmatory (n=362) factor analysis. The data were gathered by using the COVID-19-HLS and the Personal Variables Form. Language validity, content validity, item analyses, and exploratory and confirmatory factor analyses were performed to determine the validity and reliability of COVID-19-HLS.

Results:

Internal consistency reliability of the scale was found as 0.94. Item-total score correlation values of the scale were between 0.21 and 0.70, and the intra-class correlation coefficient was determined as 0.933. It was found that the item factor loads varied between 0.735 and 0.456 and the four-factor structure of the scale was found to be acceptable.

Conclusion:

In line with the analyses, it was shown that the scale is a valid and reliable instrument for Turkish society.
The Roles of Youth in Intimate Partner Relationships and the Perceived Risk of HIV Infection in South Africa
Authors: De Wet-Billings Nicole , Mabetha Khuthala , Sello Matshidiso , Makuapane Lerato
Published: November 2023

Background:

Young people in South Africa face multiple developmental challenges, including violence and HIV infection.

Objective:

This study examines the various roles of youth in violent intimate relationships (IPV) and its association with the perceived risk of HIV infection. Results from this study could assist in youth development programmes to increase HIV testing, as well as inform modifications to the South African Domestic Violence Act (No. 116 of 1998), which addresses all forms of intimate partner violence in the country.

Methods:

The study uses data from the South African National HIV Prevalence, HIV Incidence, Behaviour and Communication Survey (SABSSM) 2017. The study population is youth (15-24 years old) who responded to a question on their perceived risk of being infected with HIV. A weighted sample (N) of 1,301,550 youth is included. The main independent variable is the 'role in IPV', and the study controls for the demographic, socioeconomic, and HIV knowledge and sexual behaviours of youth. Cross-tabulations and a multivariate binary logistic regression model are used to determine the relationship between controls and the outcome.

Results:

About 20% of youth perceive themselves at risk of being with HIV. Their reasons for believing this are because they are sexually active, do not use condoms consistently, and do not trust their partners. Only about 4% of IPV perpetrators, compared to 23.71% of victims and 23.16% of bidirectional youth, think it is likely they will get infected with HIV. The odds of perceiving themselves at risk are higher (with p-values<0.05) for victims (OR=1.21), 20-24 years old (OR=1.35), female (OR=1.25), those who responded do not think condoms reduce the risk of HIV (OR=1.49) and those who do not use condoms (OR=1.44) among others.

Conclusion:

IPV behaviours are associated with perceived HIV risk among young people in South Africa. For perception to change and allow youth to adopt protective behaviours against HIV, there is a need for policy to target the different roles of youth.
Teenagers’ Perceptions of Contraception Use and Support Requirements to Prevent Teenage Pregnancies: A South African Study
Authors: Ntini Annah Maite , Rabie Tinda , Froneman Kathleen , Swart Anna-Therese
Published: November 2023

Background:

Teenage pregnancy continues to be a concern. Complications during pregnancy and childbirth are the leading causes of death among pregnant teenagers. The use of contraception and support to prevent teenage pregnancies is of utmost importance to help address this concern.

Objectives:

The study aimed to explore and describe perceptions of teenagers regarding the use of contraception (1) and what support is required in assisting teenagers to prevent teenage pregnancies (2) in Limpopo Province, South Africa.

Methods:

A qualitative research strategy employing exploratory and descriptive approaches was used in this study. Purposive sampling of teenagers in a public secondary school with the highest pregnancy rate in a district of the Limpopo Province was used. Data were collected from 23 participants using naïve sketch booklets with 12 questions. Data were analysed using content analysis with the assistance of a co-coder.

Results:

Three categories emerged from the data, namely opinion of contraception (1), factors preventing the usage of contraception (2), and help and support (3).

Conclusion:

Teenagers were knowledgeable about contraception methods, which included condoms, oral contraceptives and injectables, and the usage thereof. Advantages, disadvantages, and areas to access contraception were also known by the participants. However, there were different opinions with regards to contraception, factors preventing its usage, and help and support needed.
Self-Reported Hearing Difficulties and Hearing Aid Uptake
Authors: Oh Soo Hee
Published: November 2023

The purpose of this study is to understand self-reported hearing difficulties and hearing aid uptake with people perceiving hearing difficulties in Korea. The study investigated a total of 788 adults (mean age 67 years) with self-reported hearing difficulties during the eighth survey of Korean National Health and Nutrition Examination. The data included otolaryngology survey, pure tone hearing thresholds, and surveys on quality of life and mental health. People perceiving hearing difficulties showed reduced hearing thresholds. The prevalence of hearing aid uptake was 12.8% of people with self-reported hearing difficulties. People with mild and severe hearing difficulties showed 4.8% and 35.5% of prevalence in hearing aid uptake, respectively. The uptake of hearing aids in Korea was found to be very low. Subjective self-evaluation of hearing difficulties can be used as an indexing tool of hearing loss.