bluuebunny/crossref_metadata_2025 huggingface dataset:
A FRAMEWORK TO DEVELOP INTELLIGENT SYSTEM FOR CAPTURING PRODUCT FEATURES USING OPEN CV TECHNIQUE
Authors: Saif Yazid Abdullsameea , Yusof Yusri , Ahmed Maznah lliyas , Pathan Zohaib khan , Latif Kamran , Abdul Kadir Aini Zuhra
Published: March 2021

This research aims to propose an innovative framework using ISO14649 standard to detect defects in manufactured shaped objects or geometric surfaces of non-linear products of the CNC machine. The significant importance in order to recognize the potential to improve industry product quality inspection and encourage the waste of timing machines and product rejection. Open Computer Vision (Open CV) offers a smart, non-contact measurement and cost-effective technique to fulfil the requirements. The framework depends on the new technique of Open CV, which includes two parts: an intelligent selection of work-piece capturing the image for a particular inspection of the planar interfaces such as the hole, rectangular, pocket one, and the symmetric lighting model comparison approach for measurement of defects in the matched images. The contribution of this study is to build a structure in the computer vision method with a convolution neural network that predicts the classification of the feature for better accuracy and emphasizes the significant characteristics of the image processing technique coupled with experimental data on demanding image datasets and quality inspection measures.
IMPROVEMENT OF WORK TEMPERATURE AT CONTENT PRINTING WORKSTATION IN PUBLISHERS AND PRINTING CV GRAFIKA DUA TUJUH
Authors: Suhardi Bambang , Addina Dwinda Asyfi , Dwi Astuti Rahmaniyah
Published: March 2021

CV. Grafika Dua Tujuh is an industry engaged in publishing and printing books and student worksheets located in Klaten. The average output produced daily is 85.400 books and student worksheets, while the company has a production target of 90.000 books and student worksheets. Based on the results of interviews with workers, the level of production that is not maximal is caused by an uncomfortable working environment. Workers in the production room complained about the condition of a hot work environment so that workers feel easily tired and lack of concentration. To overcome the hot workplace, workers often go to the restroom and they work while holding the hand fan. This condition disturbed their concentration and cause work errors. If this condition is carried out continuously, there will be a lot of lost work time which can cause a decrease in productivity. This study aims to analyze the improvement of working temperature conditions in the production room of CV. Grafika Dua Tujuh. This research was conducted by directly measuring thermal conditions in the entire production room of CV. Grafika Dua Tujuh. Determination of the coordinate point of room temperature measurement is based on SNI: 16-7061-2004. Workload assessment is carried out based on SNI 7269: 2009. The results of the measurement of work climate at the content printing workstation are the values of air temperature, humidity, and wind speed i.e 33.32 °C, 39.9%, and 0 m/s. In addition, Wet Bulb Globe Temperature Index (WBGT) value is obtained which is on the verge of a limit, i.e 29.90 °C for the category of the heavy workload with an allocation of working time of 87.5%. The temperature is above the standard set by the Ministry of Health of the Republic of Indonesia No. 1405 / MENKES / 2002 which sets the temperature in an industrial room ranging from 18 °C - 28 °C. Improvement for working temperature is done by engineering control, namely the installation of a turbine ventilator or exhaust fan.
TECHNOLOGY PROGRESS IN AUTOMOTIVE SECTOR IN TERM OF ECO-FRIENDLY AND ENERGY EFFICIENT VEHICLES
Authors: Md Nor Ahmad Tarmizi , Mat Nasir Farhan , Anuar Salwa
Published: March 2021

This review paper was intended to visit the importance of sustaining the technology of eco- friendly vehicles. To understand the concept of eco-friendly we have first to understand the history of energy exploitation by human being. This review paper emphasize on the transition of energy source exploitation running thru early renaissance until the modern era we are in now. Internal Combustion Engine has served the world since early 20th century driving us into the new millennial that is the 21th century. The depletion of oil reserve indicate a utmost important for us to source for a new energy that we can exploit in abundant yet causes minimal effect to the environment. This review paper also brings in the concept of mature technology and how it can actually be a good thing that push us into innovating and creating new technology to be capable in adopting new ways in ensuring sustainability of humans by means of sustaining the technology.
The Impact of Educational Games on Enhancing Elementary Stage Students' Acquisition and Retention of English Vocabulary
Authors: Mohamed Amr Mahmoud Abdeldaim
Published: March 2021

Learning EFL vocabulary is a difficult task so that teachers try as much as possible to facilitate it for their learners. One of the best strategies that can be used is educational games strategy. The goal of this research is to check the effectiveness of using the educational games strategy in enhancing English vocabulary acquisition and retention at the First stage of basic education pupils. The study adopted the quasi-experimental pre-post test control / experimental group design. The study sample consisted of 40 pupils in sixth elementary grade and was equally divided into two groups: an experimental group and a control one. Students of the experimental group learnt vocabulary through the educational game strategy, while students in the control group received regular instruction. Tools of the study included a pre-post vocabulary achievement test and a text course for grade six named Get Ready 6. The students submitted to a pre-post vocabulary achievement test and the results indicates that there is a statistically significant difference between the mean scores of the experimental group and the control group in the pre/ post-test of English vocabulary achievement in favor of the experimental group.
Choosing to Do the Work: Thoughts on Creating an LGBTQ-Inclusive Classroom
Authors: Cherry Amanda
Published: March 2021

In this article, I aim to support teachers and other educators as they begin or continue the work of creating LGBTQ-inclusive classrooms. To support teachers, I organize my suggestions within three touchstones that have been helpful to me as a middle school language arts teacher: Choose to be vulnerable, Choose to change your instruction, Choose the work as your path. En este artículo, mi objetivo es apoyar docentes y educadores a medida que ellos inician o continúan el trabajo de crear aulas inclusivas de LGBTQ. Para apoyar a los docentes, he organizado mis sugerencias dentro de tres elementos esenciales que han sido útiles para mi como maestra de artes y lenguaje ( inglés) en la escuela media: Elige ser vulnerable, Elige cambiar tu instrucción, Elige el trabajo como tu camino.
Breaking Down the “Coatlicue State” to See a Self Queer Voices Within a Circle
Authors: Trinh Ethan
Published: March 2021

Marginalized queers have experienced the “Coatlicue State” (Anzaldúa, 2012). Seeing and being seen in front of the public are painful to us. We feel ashamed due to stereotypes placed by heteronormativity and heterosexism. In this small space, I hope to accomplish one simple thing: break down different layers of shame to ask for understanding and empathy. I write this piece to embrace us—queer marginalized voices—in schools and in academia. This dialogue will thus open doors to discussions inside and outside of a “circle”. The suggestion at the end of this article hopes to touch on insiders and outsiders of this circle. Los queers marginados han experimentado “la Herencia de Coatlicue” (Anzaldúa, 2012). Nos duele ver y ser visto frente al público. Nos sentimos avergonzados debido a los estereotipos producidos por la heteronormatividad y heterosexismo. En este pequeño espacio espero lograr una cosa muy sencilla: deconstruir las diferentes capas de vergüenza para hacer una llamada al entendimiento y la empatía. Escribo este artículo para que sean acogidas las voces marginadas queer en la escuela y la academia. Por lo tanto, este diálogo abre puertas a conversaciones dentro y fuera de un “círculo”. Con la sugerencia al final de este artículo, se espera abordar a las personas cuyas identidades se ubican adentro o afuera de este círculo.
高速公路施工中的软土路基施工技术探讨
Authors: 申 彦双
Published: March 2021

随着中国城市化的快速发展，公共交通运输道路等基础设施规划和建设项目的数量逐步增加，积极推动了当地交通运输的快速发展。在高速公路的规划和建设中，软土地基施工的核心技术更为重要。根据工程项目中出现的特殊地貌地质结构条件，改进不同的施工技术，使软土地基施工项目的核心技术更加安全可靠，提高施工质量，为施工企业自身取得了较好的经济利益。文章主要包括对高速公路软基施工单位的各种技术的探讨进行深入分析。总结了各种技术在我国软土路基处理施工单位中的应用现状，明确提出了软土路基施工中各种技术的综合优化和持续改进建议。
国省干线公路安全生命防护工程设计
Authors: 崔 启悦
Published: March 2021

公路安全生命防护工程设计及建设是确保公路交通安全运行的基本手段，可以有效保障群众的生命财产安全。基于此，本篇文章对国省干线公路安全生命防护工程设计的相关问题进行探讨。
基于科学规划城市前提的市政道路排水设计分析探讨
Authors: 范 晴
Published: March 2021

只有高质量的城市道路才能保证城市交通的良好运行。然而，市政道路的积水问题严重影响了城市交通的健康发展。基于此，本研究对市政道路排水设计进行了一系列探讨，并提出了合理化建议，以及对我国市政道路的发展作出贡献。
浅谈地铁空调系统的风水联动
Authors: 高 文鑫
Published: March 2021

随着地铁行业的发展，运营线路、车站不断增多，机电设备也随之增加。机电系统中通风空调专业作为城市轨道交通地下车站的“呼吸系统”，是保证地铁运营的先决条件。通风空调系统关注的重点是洁净和节能，洁净度可以通过除尘、空气净化等设备达到要求，风水联动控制达到节能效果是我们文中讨论的重点。在轨道交通行业中，通风空调系统约占地铁能耗的30%，仅次于牵引供电系统。地铁通风空调系统的设备一般按照远期高峰运行情况进行配置，因此设备选型有较大的富余量。在满足设备正常运转、乘客舒适度的前提下，如何实现节能降耗是我们探讨的主题。为了使通风空调系统实现有效的节能，需要不断地探索、实践和归纳。通过对地铁通风空调系统节能关键点进行分析，结合对不同工况运转条件实践后的总结，在地铁通风空调系统中归纳形成完整的逻辑控制应用，实现焓值控制和群控控制的有效结合。
浅析高速公路桥梁施工管理、养护与加固维修技术
Authors: 夏 奕凡
Published: March 2021

近年来，在多方面利好因素的影响下，城市化建设工作得到了全面的推进，在这种发展形势下各个领域的发展以及民众的生活都对公路桥梁工程的使用提出了更高的要求。为了能够为社会发展和民众的生活提供更好的服务，相关部门在公路桥梁工程方面投入了大量的人力物力，为我国公路桥梁工程建设工作的稳定持续发展打下了坚实的基础。公路桥梁工程项目施工与养护管理工作能够从不同的角度对工程质量加以保障，并且会从各个细节入手来对工程质量进行全面的把控，养护与加固维修技术的实践运用是在运营维护的层面上，切实的对公路桥梁结构失稳问题加以解决，从而为高速公路桥梁工程行业的未来健康发展给予良好的辅助。
热处理技术在压力容器设计中的应用探析
Authors: 许 晓宇 , 乔 朝坤
Published: March 2021

热处理在加工和制造金属的性质过程中，具有更好的改善作用，因此热处理技术在金属加工和制造过程中得到了广泛的应用。压力容器的设计制造对金属性能也有更高的要求，压力容器的设计制造使用热处理技术，从而有效提高压力容器整体性能。
探究路桥施工中安全管理存在的问题与解决措施
Authors: 王 伟
Published: March 2021

在建筑工程行业中安全管理是其中的重点，因此路桥工程建设过程中也应认识到安全管理的作用并将安全管理贯穿到路桥工程施工的各个环节中。只有保证安全管理效率才能确保各工序顺利进行，在进行安全管理工作时应根据工程具体情况制定出更加具体的安全管理制度，利用其提升路桥工程建设质量。路桥工程安全管理工作中还应落实相应的法律法规并保证其符合工程具体要求。因此，路桥工程施工企业在进行安全管理工作时应构建起完整的管理体系并将现行的法律法规作为指导，在各施工环节中落实安全管理工作后可以降低安全事故发生率同时还应做好安全事故预防工作，在避免安全事故发生的同时提高工程建筑质量。
国土空间规划视角下的城市总体规划改革思考
Authors: 李 淑艳
Published: March 2021

作为一项系统性的项目，城市规划在如今高速发展的社会中显得尤为重要，而且随着新事物以及新产业的不断出现，城市规划的复杂性和难度也在不断的提升，所以为了确保城市规划的质量，就必须要对规划进行全方面的考虑，依据城市自身的特点来做出科学合理的规划，确保规划具有足够的经济潜力，而且还能提高人们居住环境的宜居性和城市发展的人文性。因此在文中我们主要对国土空间规划视角下对城市总体规划进行详细的分析与探讨。
Rede Cegonha e seus impactos sobre os nascimentos em um estado do nordeste brasileiro
Authors: Barros Marcela Cristina dos Santos , Silva Rita de Cássia Ramires da , Santos Letícia de Macedo , Figueredo Eliza Vitória Nascimento , Santos Camila Thayná Oliveira dos , Carvalho Alycia Antunes de , Cabral Thainá da Silva , Oliveira Keila Cristina Pereira do Nascimento , França Alba Maria Bomfim de , Silva Jovânia Marques de Oliveira e
Published: March 2021

Objetivo: analisar o impacto da Estratégia Rede Cegonha em Alagoas sobre os nascimentos no período de 2011 a 2018. Método: estudo ecológico, de série temporal, com dados secundários oriundos do DATASUS. Os dados foram processados pelos softwares Statistical Package for the Social Sciences. Foram adotadas como variáveis o coeficiente de mortalidade entre os anos de 2011 a 2018, a relação entre a quantidade total de óbitos por causas evitáveis, através de regressão múltipla (p<0,05). Resultados: as taxas apresentaram oscilações, entretanto a rede cegonha potencializou a melhora nos indicadores de morbimortalidade. Observa-se que a maioria dos óbitos fetais poderiam ser evitados por meio de ações de redução das desigualdades sociais, mais consultas de pré-natal de alta qualidade e de melhora na qualidade da atenção obstétrica voltadas à mulher e recém-nascido. Conclusão: evidenciou-se, através da análise dos indicadores, que existe a necessidade de melhoria na atenção à saúde materno-infantil em Alagoas.
Manejo nutricional com micronutrientes e seus efeitos sobre os componentes de produtividade na cevada
Authors: Pessenti Isabela Leticia , Torres Adalci Leite , Martins Warlyton Silva , Macoski Nádia
Published: March 2021

Na cevada, a deficiência nutricional, ocasionada pelo déficit de micronutrientes, é um fator-chave que afeta negativamente a sua produtividade. Dentre os micronutrientes, o Zinco (Zn) e o Boro (B) estão sendo amplamente estudados em detrimento ao crescimento da planta, tal qual a qualidade do seu produto, os quais são favorecidos pelo suprimento balanceado desses micronutrientes. Nesta concepção, o presente trabalho objetivou avaliar a aplicação de zinco no tratamento de sementes e pleno perfilhamento e a aplicação de boro via adubação foliar, combinados ou não na cultura da cevada na Região dos Campos Gerais -PR. O delineamento foi em blocos casualizados com 4 níveis de tratamento e 4 repetições, cujas parcelas foram compostas por 5 linhas de cevada com 2 metros de comprimento e espaçadas por 0,45m, totalizando 4,5m². Os tratamentos foram: testemunha, Zn: aplicação de zinco 4ml kg-1 via tratamento de sementes e no estádio de pleno perfilhamento; B: aplicação foliar de boro no estádio R1; Zn + B: aplicação combinada de Zn e B. Foram avaliados o rendimento de grãos (com umidade corrigida para 13%), componentes do rendimento (número de espiguetas por planta, número de grãos por planta, massa de grãos por planta e massa de mil grãos), estatura de plantas e a qualidade fisiológica de sementes. Os tratamentos de zinco e boro isolados aumentaram o rendimento de grãos e os componentes de rendimento para a cultivar BRS Cauê. Os parâmetros de qualidade fisiológica também foram superiores para os tratamentos de zinco e boro aplicados isoladamente. Apenas para o peso de mil sementes o zinco aumentou significativamente. Conclui-se que a aplicação de zinco via tratamento de sementes e pleno perfilhamento, assim como a aplicação foliar de boro proporcionam maiores rendimentos e melhoria na qualidade fisiológica das sementes de cevada.
Plantas aquáticas em ecotecnologias: perspectivas para fitorremediação de ferro e manganês
Authors: Silva Dayane Mendes , Lizieri Claudineia , Oliveira Júnior Ernandes Sobreira
Published: March 2021

Fitorremediação consiste no uso de plantas para mitigação de ambientes poluídos, tanto os terrestres como os aquáticos. Embora esta ecotecnologia tem crescido consideravelmente nas últimas décadas, a expansão de sua aplicação ainda esbarra no desafio para selecionar espécies de plantas com tal potencial. Neste trabalho, duas espécies de macrófitas aquáticas, Spirodela polyrhiza e Ricciocarpus natans, foram estudadas em experimentos laboratoriais para avaliação de seu desempenho na remoção de manganês (Mn) e do ferro (Fe) em solução. Plantas de S. polyrhiza foram testadas para ambos metais e submetidas às concentrações de 10, 15, 20, 25 e 30 mg/L de Mn e Fe. Enquanto plantas de R. natans foram submetidas às concentrações de 1, 2, 6 e 18 mg/L de Fe. Os resultados mostraram que plantas de S. polyrizha foram capazes de remover 34% do Mn e até 80% do Fe adicionados na solução. Entretanto, a redução da biomassa e do conteúdo de clorofila foi detectada nessas plantas.  As plantas de R. natans, removeram até 50% do Fe nas concentrações de 2, 6 e 18 mg/L e não demonstraram queda da biomassa e clorofila em nenhuma das concentrações testadas, evidenciando resultados promissores para a fitorremediação de Fe. Estudos com experimentos de campo são necessários para considerar as variantes ambientais envolvidas no processo de remediação. No entanto, os achados aqui apresentados trazem, à luz da ciência, contribuições significantes para o conhecimento fitorremediador de S. polyrizha e R. natans, espécies aquáticas amplamente distribuídas nos corpos d’ água brasileiros.
Permeabilidade da membrana plasmática celular da beterraba: uma proposta de aula prática no ensino médio
Authors: Gonçalves Tiago Maretti
Published: March 2021

A membrana plasmática é uma estrutura de grande importância presente em todos os seres vivos, desempenhando além do transporte de substâncias, diversas outras funções. O presente artigo possui como principal objetivo propor uma aula prática para facilitar o processo norteador do ensino e da aprendizagem da membrana celular aos alunos do ensino médio, na disciplina de Biologia. Utilizando materiais simples e de baixo custo como beterraba (Beta vulgaris, L.), água, querosene e álcool, essa aula permite ao professor trabalhar com os alunos os conceitos de permeabilidade da membrana, além de outros assuntos relacionados. Assim, a aula prática proposta pode ser reproduzida não somente no ambiente escolar, mas também em casa pelos discentes. Acreditamos que, a abordagem da aula prática proposta possa permitir a aplicação dos conceitos vivenciados nas aulas teóricas, facilitando a aprendizagem do tema proposto, além de promover a discussão e a proposição de hipóteses, despertando a ótica de experimentação científica dos discentes.
Temperature Effect on Listeria Monocytogenes Planktonic Growth and Biofilm-Forming Ability
Authors:   University of Lisbon, Portugal., Andrade Joana Catarina , Bernardo Rita ,   University of Lisbon, Portugal., Barreto António Salvador ,   Technical University of Lisbon, Portugal., Nunes Telmo ,   Technical University of Lisbon, Portugal, Henriques Ana Rita ,   University of Lisbon, Portugal.
Published: March 2021

Listeria Monocytogenes is an important foodborne pathogen with the capacity to grow at low temperatures and the ability to form biofilms. These features are particularly significant to food business operators producing readyto-eat foods with a long refrigerated shelf-life not undergoing any listericidal treatment before consumption. Objectives: This work aims to assess the temperature effect on L. monocytogenes growth in planktonic suspension and in mono-species biofilms. Methods and results: Isothermal planktonic growth at 12o C and 37o C was assayed using viable cell counts and optical density measurements that revealed a strong positive correlation, confirming the reliability of combining both methods to estimate L. monocytogenes concentration. Experimental data were then fitted to Baranyi and Roberts primary predictive model and the estimated growth parameters confirmed that μmax at 37o C (0.375 ± 0.072 log Cfu/ ml/h) was higher than at 120 C (0.054 ± 0.001 log Cfu/ml/h), with identical L. monocytogenes final concentrations which emphasizes its ability to grow at refrigerated temperatures. Experimental results from the isothermal growth assay and ComBase Predictor growth model were similar, with slightly higher estimated μmax (37o C: 0.480 log Cfu/ml/h; 12o C: 0.068 log Cfu/ml/h) in the predictor growth model. The studied strains demonstrated biofilm-forming ability at 12o C, 20o C and 300 C after 5 days of growth. No significant differences in biofilm formation at different temperatures were detected considering viable cell counts values, but when using crystal violet staining optical density results significant differences were found, with the highest formation occurring at 30ºC. A positive strong correlation was found between viable cell counts and crystal violet staining optical density results. In fact, both methods complement each other, because while viable cell counts measures viable cells, crystal violet staining optical density considers total biomass (viable and non-viable cells and extracellular matrix components). Nevertheless, in this work all L. monocytogenes strains revealed to be weak biofilm producers. Conclusion: Overall, this studys results contribute with important initial information on L. monocytogenes growth and biofilm formation to further assist predictive growth modeling in food matrices and environments, also enabling subsequent quantitative microbial risk assessment, to improve pathogen’s control.
Poor People's Energy Outlook 2019 Arabic: Enabling energy access from village to nation
Authors:   Practical Action, Denning Rosanna
Published: March 2021

With just a decade to go until the deadline for our 2030 Global Goals, universal energy access remains elusive. PPEO 2019 explores progress achieved to date - and considers what remains to be done, to ensure that we truly leave no one behind behind in our pursuit of SDG7.
Machos, Maricones, and Gays: Cuba and Homosexuality
Authors: Lumsden Ian
Published: March 2021

Since the Cuban revolution in 1959, male homosexuality has been a controversial aspect of Cuban society. In this account of homosexual life, Ian Lumsden explores the treatment of male homosexuality under Castro within the framework of pre-revolution prejudices and preconceptions.
The Effect of Class Management on Economic Learning Motivation at SMA Negeri 20 Palembang
Authors: Yulaini Erma , Rachmawati Diana Widhi , Putri Devi Nur Ahini Oktavia , Chayanti Nyoman Tri
Published: March 2021

The purpose of this study was to determine the effect of classroom management on motivation to study economics at SMA Negeri 20 Palembang for the 2019/2020 academic year. The research method used quantitative descriptive method. The sample in the research of class X amounted to 54 students. In collecting data the researchers used techniques of documentation and questionnaires. The results showed that the class management had a significant effect on the economic learning motivation received with a large effect from the class management of 31.97%, while the remaining 68.03% was influenced by other factors. Therefore, classroom management is needed in the learning process.

Keywords: Classroom Management, Learning Motivation, Management Education
Poets in a Transnatural Landscape: Coleridge, Nature, Poetry
Authors: Leadbetter Gregory
Published: March 2021

This essay addresses the nature of the experience of nature, as evoked, in particular, by Coleridge, and the relationship between that experience and the impulse to speak of it, especially in poetry. Always a fascinated observer of his own responsiveness, he wrote to Thomas Wedgwood in 1802 that ‘I never find myself alone within the embracement of rocks & hills, a traveller up an alpine road, but my spirit courses, drives, and eddies, like a Leaf in Autumn: a wild activity, of thoughts, imaginations, feelings, and impulses of motion, rises up from within me’. As in his verse, the rhythmic motility of these lines, so characteristic of his language, cannot bear a merely consequential correspondence to the contours of landscape: not everyone who moves through such territory writes like Coleridge. With reference to his poetry, criticism, notebooks and letters, this essay examines the more complex relation to landscape at work in Coleridge's language: the connection between the ineffable character of sensory experience and the effusion of utterance; the participatory character of Coleridge's engagement with the natural world; the irruptive, ecstatic and synaesthetic qualities of his writing with regard to landscape; and the paradoxical desire both to name and not to name, to know and unknow, imprinted in his poetry. In doing so, the essay contends for the presence in Coleridge's work of a psychotropic poetics related to the nature of his experience of the natural order, in which poetry has the potential to act as a maker of ‘nature’ – like the natural world itself, an educative stimulus to our epistemic, empathetic and creative powers – and as such, transnatural.

Friedrich Schlegel made the suggestive remark that ‘one cannot really speak of poetry except in the language of poetry’, and the essay concludes with a poem of my own germane to its theme.
‘Spain! Most Pleasant were my wanderings’: Robert Southey's Pedestrian and Mountaineering Writing in the Iberian Peninsula
Authors: Flores Cristina
Published: March 2021

This article explores Robert Southey's literary responses to his walking experiences in Spain as he recounted them in Letters Written During a Short Residence in Spain and Portugal (1797). Published after a four-month visit to the Iberian Peninsula, Letters departs from previous travelogues in offering, apart from factual details, subjective impressions of the places visited both in prose and verse. Nonetheless, I argue, Southey adopts a more intimate and self-reflective mood when he relates his pedestrian excursions in verse, not only showing a deeper aesthetic engagement with the natural surroundings but also acquiring an inward look. Moved by the bodily exertion of walking and hill climbing in Spain, Southey produced a series of poems in which the fragility of memory, the feelings of isolation and distress and the related poetic incapacity are explored. Encompassing examples from Coleridge's and Wordsworth's poems, in this essay I read Southey's poems in Letters as aligned with and contributing to the then emerging Romantic pedestrian poetics, though at the same time showing their ideosyncracy derived from Southey's complex approach to the Other in ‘a land of strangers’.
Bartın İlinde Yetiştirilen Fındığın (Corylus avellana L.) Zurufunun (Yeşil Yapraklı Kabuk) Antioksidan Özelliklerinin İncelenmesi
Authors: KURTÇA Mehmet
Published: March 2021

Antioksidanlar insan vücudunda biriken serbest radikalleri temizleyerek, vücudun çeşitli hastalıklardan korunmasını sağlayan önemli yapılardır. Vücutta enzim, hormon ve protein olarak birçok antioksidan mevcuttur. Bunların dışında doğal olarak birçok besinde bulunan vitaminler, tanenler, fenolik asitler, flavonoidler gibi çok sayıda antioksidan madde de vardır. Fındık antioksidan madde içeren besinlerin başında gelmektedir. Ülkemizde bolca yetişen ve ülke ekonomisine katkı sağlayan bir bitkidir. Fındık hasadı ve işlenmesi sırasında zuruf, kabuk, iç zar gibi yan ürünlerde ortaya çıkmakta ve bu ürünlerden çok fazla ekonomik katkı sağlanamamaktadır. Bu çalışma fındık yan ürünü olan zurufun da yüksek antioksidan özelliğe sahip olduğunu ve sanayide farklı alanlarda kullanılarak ekonomiye katkı sağlanabileceğini göstermek amacıyla yapılmıştır. Bu amaç doğrultusunda Bartın ilinde yetiştirilen tombul fındık (Corylus avellana L.) türünün zurufları taze olarak toplanmış, su, su-aseton, aseton ve etanol gibi farklı çözücülerle ekstresi elde edilmiştir. Elde edilen ekstrelerin toplam fenolik, ve flavonoid miktarı, DPPH serbest radikal süpürücü aktivite, ABTS katyon radikal giderim aktivitesi ve Bakır (II) indirgeme antioksidan kapasitesi tayinlerine (CUPRAC) bakılmıştır. Sonuçlar incelendiğinde fındık zurufunun yüksek antioksidan özelliğe sahip olduğu görülmüştür. Ayrıca su-aseton ekstresinin, diğer ekstrelere göre toplam fenolik miktar (273.56±10.12 mg/g ekstre), DPPH (18.74±0.87 µg/ml), ABTS (4.78±0.56 µg/ml) ve CUPRAC (8.74±2.13 µg/ml) aktivitelerinde en iyi sonucu verdiği tespit edilmiştir.
Controlling Cancer Cell Behavior by Improving the Stiffness of Gastric Tissue-Decellularized ECM Bioink With Cellulose Nanoparticles
Authors: Kim Jisoo , Jang Jinah , Cho Dong-Woo
Published: March 2021

A physiologically relevant tumor microenvironment is favorable for the progression and growth of gastric cancer cells. To simulate the tumor-specific conditions of in vivo environments, several biomaterials engineering studies have investigated three-dimensional (3D) cultures. However, the implementation of such cultures remains limited because of challenges in outlining the biochemical and biophysical characteristics of the gastric cancer microenvironment. In this study, we developed a 3D cell printing-based gastric cancer model, using a combination of gastric tissue-specific bioinks and cellulose nanoparticles (CN) to provide adequate stiffness to gastric cancer cells. To create a 3D gastric tissue-specific microenvironment, we developed a decellularization process for a gastric tissue-derived decellularized extracellular matrix (g-dECM) bioink, and investigated the effect of the g-dECM bioink on promoting the aggressiveness of gastric cancer cells using histological and genetic validation methods. We found that incorporating CN in the matrix improves its mechanical properties, which supports the progression of gastric cancer. These mechanical properties are distinguishing characteristics that can facilitate the development of an in vitro gastric cancer model. Further, the CN-supplemented g-dECM bioink was used to print a variety of free-standing 3D shapes, including gastric rugae. These results indicate that the proposed model can be used to develop a physiologically relevant gastric cancer system that can be used in future preclinical trials.
Revival of Leishmanization and Leishmanin
Authors: Pacheco-Fernandez Thalia , Volpedo Greta , Gannavaram Sreenivas , Bhattacharya Parna , Dey Ranadhir , Satoskar Abhay , Matlashewski Greg , Nakhasi Hira L.
Published: March 2021

Leishmaniasis includes a spectrum of diseases ranging from debilitating cutaneous to fatal visceral infections. This disease is caused by the parasitic protozoa of the genusLeishmaniathat is transmitted by infected sandflies. Over 1 billion people are at risk of leishmaniasis with an annual incidence of over 2 million cases throughout tropical and subtropical regions in close to 100 countries. Leishmaniasis is the only human parasitic disease where vaccination has been successful through a procedure known as leishmanization that has been widely used for decades in the Middle East. Leishmanization involved intradermal inoculation of liveLeishmania majorparasites resulting in a skin lesion that following natural healing provided protective immunity to re-infection. Leishmanization is however no longer practiced due to safety and ethical concerns that the lesions at the site of inoculation that can last for months in some people. New genome editing technologies involving CRISPR has now made it possible to engineer safer attenuated strains ofLeishmania, which induce protective immunity making way for a second generation leishmanization that can enter into human trials. A major consideration will be how the test the efficacy of a vaccine in the midst of the visceral leishmaniasis elimination program. One solution will be to use the leishmanin skin test (LST) that was also used for decades to determine exposure and immunity to Leishmania. The LST involves injection of antigen fromLeishmaniain the skin dermis resulting in a delayed type hypersensitivity (DTH) immune reaction associated with a Th1 immune response and protection against visceral leishmaniasis. Reintroduction of novel approaches for leishmanization and the leishmanin skin test can play a major role in eliminating leishmaniasis.
Overcoming Challenges to Teamwork in Healthcare: A Team Effectiveness Framework and Evidence-Based Guidance
Authors: Zajac Stephanie , Woods Amanda , Tannenbaum Scott , Salas Eduardo , Holladay Courtney L.
Published: March 2021

Background:Safe and effective patient care depends on the teamwork of multidisciplinary healthcare professionals. Unfortunately, the field currently lacks an evidence-based framework for effective teamwork that can be incorporated into medical education and practice across health professions. We introduce a comprehensive framework for team effectiveness. Common challenges to teamwork in healthcare are identified along with evidence-based strategies for overcoming them.

Methods:The framework was developed in four steps: 1) grounding in the existing team science literature, 2) semi-structured interviews (N= 13), 3) thematic analysis and initial framework development, and 4) revision of the framework through input from healthcare professionals representative of different functions across the healthcare system (N= 13). A diagnostic tool consisting of one survey item per team competency was developed to complement the framework. The survey was then administered to healthcare teams across clinical and administrative functions (N= 10 teams, 96 individuals), and results were compiled and then used to conduct debriefs with individual team members and teams. A set of common teamwork challenges were identified using the survey and qualitative data. Qualitative data was analyzed to explore the unique ways these challenges manifest in both clinical and administrative teams.

Results:The five most common challenges that face healthcare teams relate to accountability, conflict management, decision-making, reflecting on progress, and coaching. These challenges were similar across both clinical and administrative team types. Based on the authors' collective experience designing and implementing Team Development Interventions (TDIs), strategies for managing each challenge are provided.

Conclusions:The proposed framework is unique in two ways. First, it's generally applicable across the many types of teams that contribute to the quality and safety of patient care. Second, the levels of the framework build upon each other to contribute to the development of the ideal team states. The framework and accompanying strategies can provide guidance for where and how to target developmental efforts.
Conceptualising Primary-Secondary School Transitions: A Systematic Mapping Review of Worldviews, Theories and Frameworks
Authors: Jindal-Snape Divya , Symonds Jennifer E. , Hannah Elizabeth F. S. , Barlow William
Published: March 2021

There is continued interest internationally in primary-secondary school transitions. Fourteen literature reviews of primary-secondary transitions have been published over the last 20 years, however none of them have systematically analysed primary-secondary school transition ontology, i.e., researchers’ worldviews, theories/models and frameworks. This is a major gap in these reviews and the papers published in this area; this is of concern as it is difficult to trust the robustness of a study if its foundation, such as researchers’ conceptualisation of transitions, is not visible. Therefore, using the Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre) approach, we undertook a systematic mapping review, of empirical studies published internationally between 2008 and 2018. Our objectives were to explore researchers’ and research participants’ conceptualisation of transitions, the conceptual framework used by the researchers and their discourse about transitions. Of the 96 studies included in this systematic mapping review, most had not clearly defined transition, and even when conceptualisation was explicit, it did not underline the research design or frame the findings. Most researchers adopted previously used theoretical frameworks.These theoretical frameworks can be beneficial; however, as the researchers did not adapt or develop them in the context of transitions research, it limits a meta-theoretical understanding of transitions. Further, the majority did not report study participants’conceptualisation of transitions. Similarly, a large number of researchers adopted a negative discourse about primary-secondary school transitions, with some using a mixed discourse and only two papers had a primarily positive discourse. This systematic mapping review is original and significant as it is the first study to provide a review of school transitions ontology and offers unique insights into the conceptual and methodological gaps that international transitions researchers should address.
Australian Social Work Academics Respond to International Students in Crisis During COVID-19
Authors: Fronek Patricia , Briggs Lynne , Liang Jianqiang , Gallagher Hilary , Doherty Ainsley , Charles Bronwyn , McDonald Shane
Published: March 2021

This article discusses the impact of COVID-19 on a cohort of international students studying at one Australian university and the efforts made by social work academics to assist these students through a challenging and distressing time between December 2019 and July 2020. International social work students usually rely on scholarships and casual employment to support themselves while studying. Nonetheless, the Australian government made no financial provisions for international students when the COVID-19 pandemic struck leaving many students without any means of support. Students from all parts of the world attend Griffith University, located in south-east Queensland, Australia, including students from Wuhan, China, where the first known outbreak of COVID-19 was identified. Shame, anxiety, racism and concerns related to the wellbeing of families overseas were superimposed onto their own health concerns and day-to-day survival while still seeking to maintain academic progress. Material and emotional support were provided through the establishment of a food bank and the development of a case management model to address the needs of students. A COVID-19 Alternative Placement course and a field education student hub supported academic success during the health emergency. These interventions developed independently as a crisis response and were merged into a multi-pronged, coordinated approach that included collaborations with other sections of the university and the community. A School working committee was established to co-ordinate interventions to address individual student need that included crisis intervention, referrals to internal and external resources, and developing communities of support. The journey traveled by students and academics and the lessons learned from this experience are described, all of which are relevant to future health emergencies including the value of involving social work in university preparedness planning. The article concludes that intensive support can enhance resilience while supporting students’ own survival strategies, and, importantly, how such efforts can minimize, as far as possible, disruption to academic progress.
Mechanistic Targets and Nutritionally Relevant Intervention Strategies to Break Obesity–Breast Cancer Links
Authors: Bustamante-Marin Ximena M. , Merlino Jenna L. , Devericks Emily , Carson Meredith S. , Hursting Stephen D. , Stewart Delisha A.
Published: March 2021

The worldwide prevalence of overweight and obesity has tripled since 1975. In the United States, the percentage of adults who are obese exceeds 42.5%. Individuals with obesity often display multiple metabolic perturbations, such as insulin resistance and persistent inflammation, which can suppress the immune system. These alterations in homeostatic mechanisms underlie the clinical parameters of metabolic syndrome, an established risk factor for many cancers, including breast cancer. Within the growth-promoting, proinflammatory milieu of the obese state, crosstalk between adipocytes, immune cells and breast epithelial cells occurs via obesity-associated hormones, angiogenic factors, cytokines, and other mediators that can enhance breast cancer risk and/or progression. This review synthesizes evidence on the biological mechanisms underlying obesity-breast cancer links, with emphasis on emerging mechanism-based interventions in the context of nutrition, using modifiable elements of diet alone or paired with physical activity, to reduce the burden of obesity on breast cancer.
Enhanced Dynamic Behaviour of Grid Connected Wind Farms in Load Participation and Frequency Regulation
Authors: Okedu Kenneth E. , Barghash Hind F. A.
Published: March 2021

The control of grid frequency in power systems due to the penetration of wind turbines is vital to maintaining the stability of power grids, based on recent grid requirements. In this paper, the dynamic behaviour of a wind farm connected to an existing grid is presented. The existing grid is made up of steam turbines, while the wind farm is based on squirrel cage induction generators. An energy capacitor system is used to stabilize the wind farm during periods of wind speed change. Loads with various capacities were connected to the grid to test the robustness of the controllers of the energy capacitor system employed. Furthermore, the effect of varying the time constant of the in-built DC-DC chopper of the energy capacitor system was investigated, considering load participation in the grid. One of the targets of this paper is the stabilization of the grid frequency of the network, despite the load capacity and the nature of the wind speed in the wind farm. The system performance was evaluated using Power System Computer Design and Electromagnetic Transient Including DC (PSCAD/EMTDC). The same conditions of operation were used to investigate the various scenarios considered in this study, to ensure an effective comparison. The natural wind speed employed was the same for all the considered scenarios. The presented results show that small load capacity with a high value low pass filter time constant, provided better response for the grid frequency and the entire variables of the power network.
Macroeconomic Uncertainty and Crude Oil Futures Volatility–Evidence from China Crude Oil Futures Market
Authors: Yi Adan , Yang Menglong , Li Yongshan
Published: March 2021

This paper investigates whether the macroeconomic uncertainty factors can explain and forecast China’s INE crude oil futures market volatility. We use the GARCH-MIDAS model to investigate the explaining and predicting power of the macroeconomic uncertainties. We considered various geopolitical risk (GPR) indices, economic policy uncertainty (EPU) indices, and infectious disease pandemic (IDEMV) indices in our model. The empirical results suggest that the geopolitical risk, the geopolitical act risk, the global economic policy uncertainty, the economic policy uncertainty from the United Kingdom, and the economic policy uncertainty from Japan comprehensively integrate the information contained in the rest factors, and have superior predictive powers for INE crude oil future volatility. These findings highlight the importance of the impact of macroeconomic uncertainty factors has on the crude oil futures market, and indicate that the macroeconomic uncertainties need to be considered when explaining and forecasting crude oil futures market volatility.
Transcriptome Analysis Identifies Candidate Genes and Signaling Pathways Associated With Feed Efficiency in Xiayan Chicken
Authors: Xiao Cong , Deng Jixian , Zeng Linghu , Sun Tiantian , Yang Zhuliang , Yang Xiurong
Published: March 2021

Feed efficiency is an important economic factor in poultry production, and the rate of feed efficiency is generally evaluated using residual feed intake (RFI). The molecular regulatory mechanisms of RFI remain unknown. Therefore, the objective of this study was to identify candidate genes and signaling pathways related to RFI using RNA-sequencing for low RFI (LRFI) and high RFI (HRFI) in the Xiayan chicken, a native chicken of the Guangxi province. Chickens were divided into four groups based on FE and sex: LRFI and HRFI for males and females, respectively. We identified a total of 1,015 and 742 differentially expressed genes associated with RFI in males and females, respectively. The 32 and 7 Gene Ontology (GO) enrichment terms, respectively, identified in males and females chiefly involved carbohydrate, amino acid, and energy metabolism. Additionally, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis identified 11 and 5 significantly enriched signaling pathways, including those for nutrient metabolism, insulin signaling, and MAPK signaling, respectively. Protein–protein interaction (PPI) network analysis showed that the pathways involving CAT, ACSL1, ECI2, ABCD2, ACOX1, PCK1, HSPA2, and HSP90AA1 may have an effect on feed efficiency, and these genes are mainly involved in the biological processes of fat metabolism and heat stress. Gene set enrichment analysis indicated that the increased expression of genes in LRFI chickens was related to intestinal microvilli structure and function, and to the fat metabolism process in males. In females, the highly expressed set of genes in the LRFI group was primarily associated with nervous system and cell development. Our findings provide further insight into RFI regulation mechanisms in chickens.
Exome-Wide Search for Genes Associated With Central Nervous System Inflammatory Demyelinating Diseases Following CHIKV Infection: The Tip of the Iceberg
Authors: Alves-Leon Soniza Vieira , Ferreira Cristina dos Santos , Herlinger Alice Laschuk , Fontes-Dantas Fabricia Lima , Rueda-Lopes Fernanda Cristina , Francisco Ronaldo da Silva , Gonçalves João Paulo da Costa , de Araújo Amanda Dutra , Rêgo Cláudia Cecília da Silva , Higa Luiza Mendonça , Gerber Alexandra Lehmkuhl , Guimarães Ana Paula de Campos , de Menezes Mariane Talon , de Paula Tôrres Marcelo Calado , Maia Richard Araújo , Nogueira Bruno Miceli Gonzalez , França Laise Carolina , da Silva Marcos Martins , Naurath Christian , Correia Aline Saraiva da Silva , Vasconcelos Claudia Cristina Ferreira , Tanuri Amilcar , Ferreira Orlando Costa , Cardoso Cynthia Chester , Aguiar Renato Santana , de Vasconcelos Ana Tereza Ribeiro
Published: March 2021

Chikungunya virus (CHIKV) is a re-emergent arbovirus that causes a disease characterized primarily by fever, rash and severe persistent polyarthralgia, although <1% of cases develop severe neurological manifestations such as inflammatory demyelinating diseases (IDD) of the central nervous system (CNS) like acute disseminated encephalomyelitis (ADEM) and extensive transverse myelitis. Genetic factors associated with host response and disease severity are still poorly understood. In this study, we performed whole-exome sequencing (WES) to identify HLA alleles, genes and cellular pathways associated with CNS IDD clinical phenotype outcomes following CHIKV infection. The cohort includes 345 patients of which 160 were confirmed for CHIKV. Six cases presented neurological manifestation mimetizing CNS IDD. WES data analysis was performed for 12 patients, including the CNS IDD cases and 6 CHIKV patients without any neurological manifestation. We identified 29 candidate genes harboring rare, pathogenic, or probably pathogenic variants in all exomes analyzed. HLA alleles were also determined and patients who developed CNS IDD shared a common signature with diseases such as Multiple sclerosis (MS) and Neuromyelitis Optica Spectrum Disorders (NMOSD). When these genes were included in Gene Ontology analyses, pathways associated with CNS IDD syndromes were retrieved, suggesting that CHIKV-induced CNS outcomesmay share a genetic background with other neurological disorders. To our knowledge, this study was the first genome-wide investigation of genetic risk factors for CNS phenotypes in CHIKV infection. Our data suggest that HLA-DRB1 alleles associated with demyelinating diseases may also confer risk of CNS IDD outcomes in patients with CHIKV infection.
Single Cell Analysis of Blood Mononuclear Cells Stimulated Through Either LPS or Anti-CD3 and Anti-CD28
Authors: Lawlor Nathan , Nehar-Belaid Djamel , Grassmann Jessica D.S. , Stoeckius Marlon , Smibert Peter , Stitzel Michael L. , Pascual Virginia , Banchereau Jacques , Williams Adam , Ucar Duygu
Published: March 2021

Immune cell activation assays have been widely used for immune monitoring and for understanding disease mechanisms. However, these assays are typically limited in scope. A holistic study of circulating immune cell responses to different activators is lacking. Here we developed a cost-effective high-throughput multiplexed single-cell RNA-seq combined with epitope tagging (CITE-seq) to determine how classic activators of T cells (anti-CD3 coupled with anti-CD28) or monocytes (LPS) alter the cell composition and transcriptional profiles of peripheral blood mononuclear cells (PBMCs) from healthy human donors. Anti-CD3/CD28 treatment activated all classes of lymphocytes either directly (T cells) or indirectly (B and NK cells) but reduced monocyte numbers. Activated T and NK cells expressed senescence and effector molecules, whereas activated B cells transcriptionally resembled autoimmune disease- or age-associated B cells (e.g., CD11c, T-bet). In contrast, LPS specifically targeted monocytes and induced two main states: early activation characterized by the expression of chemoattractants and a later pro-inflammatory state characterized by expression of effector molecules. These data provide a foundation for future immune activation studies with single cell technologies (https://czi-pbmc-cite-seq.jax.org/).