bluuebunny/crossref_metadata_2025 huggingface dataset:
Serological Investigation and Genetic Characteristics of Pseudorabies Virus between 2019 and 2021 in Henan Province of China
Authors: Chen Ximeng , Li Hongxuan , Zhu Qianlei , Chen Hongying , Wang Zhenya , Zheng Lanlan , Liu Fang , Wei Zhanyong
Published: August 2022

In late 2011, severe pseudorabies (PR) outbreaks occurred among swine herds vaccinated with the Bartha-K61 vaccine in many provinces of China, causing enormous economic losses for the pork industry. To understand the epidemic profile and genetic characteristics of the pseudorabies virus (PRV), a total of 35,796 serum samples were collected from 1090 pig farms of different breeding scales between 2019 and 2021 in the Henan province where swine had been immunized with the Bartha-K61 vaccine, and PRV glycoprotein E (gE)-specific antibodies were detected using an enzyme-linked immunosorbent assay (ELISA). The results reveal that the overall positive rate for PRV gE antibodies was 20.33% (7276/35,796), which decreased from 25.00% (2596/10,385) in 2019 to 16.69% (2222/13,315) in 2021, demonstrating that PR still existed widely in pig herds in the Henan province but displayed a decreasing trend. Further analysis suggested that the PRV-seropositive rate may be associated with farm size, farm category, quarter, region and the cross-regional transportation of livestock. Moreover, the gE gene complete sequences of 18 PRV isolates were obtained, and they shared a high identity (97.1–100.0%) with reference strains at the nucleotide level. Interestingly, the phylogenetic analysis based on the gE complete sequences found that there were both classical strains and variant strains in pig herds. The deduced amino acid sequence analysis of the gE gene showed that there were unique amino acids in the classical strains, the variant strains and genotype Ⅱ strains. This study provides epidemiological data that could be useful in the prevention of pseudorabies in Henan, China, and this finding contributed to our understanding of the epidemiology and evolution of PRV.
Detection of Equus Caballus Papillomavirus Type-2 in Asymptomatic Italian Horses
Authors: Cappelli Katia , Ciucis Chiara Grazia De , Mecocci Samanta , Nervo Tiziana , Crescio Maria Ines , Pepe Marco , Gialletti Rodolfo , Pietrucci Daniele , Migone Laura Federica , Turco Silvia , Mechelli Luca , Passamonti Fabrizio , Drago Carlo , Donato Gian Guido , Varello Katia , Modesto Paola , Chillemi Giovanni , Ghelardi Alessandro , Razzuoli Elisabetta
Published: August 2022

Equine Papillomavirus 2 (EcPV2) is responsible for squamous cell carcinomas (eSCCs) of external genitalia of both male and female horses. However, few studies report the EcPV2 prevalence among healthy horses. Currently, the lack of these data does not permit identifying at-risk populations and, thus, developing screening protocols aimed at the early detection of the infection, as for humans. The aim of our study was to estimate the genoprevalence of EcPV2 in clinically healthy horses in Italy and to evaluate their innate immune response. For this purpose, penile and vulvar swabs of 234 healthy horses were collected through sampling with sterile cytobrushes. Nucleic acids were isolated and EcPV2-L1 presence (DNA) and gene expression (RNA) were checked by RT-qPCR. Our results showed EcPV2-L1 DNA presence in 30.3% of the samples and L1 expression in 48% of the positive samples. No statistically significant differences were found in genoprevalence in relation to sex, age, and origin, while, concerning breeds, the Thoroughbred had the highest risk of infection. Concerning specifically the mares, 40.2% of them resulted in being positive for EcPV2; our findings show a major positivity in pluriparous (p = 0.0111) and mares subjected to natural reproduction (p = 0.0037). Moreover, samples expressing L1 showed an increased expression of IL1B (p = 0.0139) and IL12p40 (p = 0.0133) and a decreased expression of RANKL (p = 0.0229) and TGFB (p = 0.0177). This finding suggests the presence of an effective immune response, which could explain the low incidence of SCCs in positive horses, despite a high EcPV2 genoprevalence (30%).
Spatially Segregated Transmission of Co-Occluded Baculoviruses Limits Virus–Virus Interactions Mediated by Cellular Coinfection during Primary Infection
Authors: Pazmiño-Ibarra Verónica , Herrero Salvador , Sanjuan Rafael
Published: August 2022

The occlusion bodies (OBs) of certain alphabaculoviruses are polyhedrin-rich structures that mediate the collective transmission of tens of viral particles to the same insect host. In addition, in multiple nucleopolyhedroviruses, occlusion-derived virions (ODVs) form nucleocapsid aggregates that are delivered to the same host cell. It has been suggested that, by favoring coinfection, this transmission mode promotes evolutionarily stable interactions between different baculovirus variants. To quantify the joint transmission of different variants, we obtained OBs from cells coinfected with two viral constructs, each encoding a different fluorescent reporter, and used them for inoculating Spodoptera exigua larvae. The microscopy analysis of midguts revealed that the two reporter genes were typically segregated into different infection foci, suggesting that ODVs show limited ability to promote the co-transmission of different virus variants to the same host cell. However, a polyhedrin-deficient mutant underwent inter-host transmission by exploiting the OBs of a fully functional virus and re-acquired the lost gene through recombination, demonstrating cellular coinfection. Our results suggest that viral spatial segregation during transmission and primary infection limits interactions between different baculovirus variants, but that these interactions still occur within the cells of infected insects later in infection.
Evolutionary Conservation of PP2A Antagonism and G2/M Cell Cycle Arrest in Maedi-Visna Virus Vif
Authors: Luperchio Adeline M. , Jónsson Stefán R. , Salamango Daniel J.
Published: August 2022

The canonical function of lentiviral Vif proteins is to counteract the mutagenic potential of APOBEC3 antiviral restriction factors. However, recent studies have discovered that Vif proteins from diverse HIV-1 and simian immunodeficiency virus (SIV) isolates degrade cellular B56 phosphoregulators to remodel the host phosphoproteome and induce G2/M cell cycle arrest. Here, we evaluate the conservation of this activity among non-primate lentiviral Vif proteins using fluorescence-based degradation assays and demonstrate that maedi-visna virus (MVV) Vif efficiently degrades all five B56 family members. Testing an extensive panel of single amino acid substitution mutants revealed that MVV Vif recognizes B56 proteins through a conserved network of electrostatic interactions. Furthermore, experiments using genetic and pharmacologic approaches demonstrate that degradation of B56 proteins requires the cellular cofactor cyclophilin A. Lastly, MVV Vif-mediated depletion of B56 proteins induces a potent G2/M cell cycle arrest phenotype. Therefore, remodeling of the cellular phosphoproteome and induction of G2/M cell cycle arrest are ancient and conserved functions of lentiviral Vif proteins, which suggests that they are advantageous for lentiviral pathogenesis.
The Effects of Cucumber Mosaic Virus and Its 2a and 2b Proteins on Interactions of Tomato Plants with the Aphid Vectors Myzus persicae and Macrosiphum euphorbiae
Authors: Arinaitwe Warren , Guyon Alex , Tungadi Trisna D. , Cunniffe Nik J. , Rhee Sun-Ju , Khalaf Amjad , Mhlanga Netsai M. , Pate Adrienne E. , Murphy Alex M. , Carr John P.
Published: August 2022

Cucumber mosaic virus (CMV), a major tomato pathogen, is aphid-vectored in the non-persistent manner. We investigated if CMV-induced volatile organic compounds (VOCs) or other virus-induced cues alter aphid–tomato interactions. Y-tube olfactometry showed that VOCs emitted by plants infected with CMV (strain Fny) attracted generalist (Myzus persicae) and Solanaceae specialist (Macrosiphum euphorbiae) aphids. Myzus persicae preferred settling on infected plants (3 days post-inoculation: dpi) at 1h post-release, but at 9 and 21 dpi, aphids preferentially settled on mock-inoculated plants. Macrosiphum euphorbiae showed no strong preference for mock-inoculated versus infected plants at 3 dpi but settled preferentially on mock-inoculated plants at 9 and 21 dpi. In darkness aphids showed no settling or migration bias towards either mock-inoculated or infected plants. However, tomato VOC blends differed in light and darkness, suggesting aphids respond to a complex mix of olfactory, visual, and other cues influenced by infection. The LS-CMV strain induced no changes in aphid–plant interactions. Experiments using inter-strain recombinant and pseudorecombinant viruses showed that the Fny-CMV 2a and 2b proteins modified tomato interactions with Macrosiphum euphorbiae and Myzus persicae, respectively. The defence signal salicylic acid prevents excessive CMV-induced damage to tomato plants but is not involved in CMV-induced changes in aphid–plant interactions.
The Viral Origin of Human Breast Cancer: From the Mouse Mammary Tumor Virus (MMTV) to the Human Betaretrovirus (HBRV)
Authors: Bevilacqua Generoso
Published: August 2022

A Human Betaretrovirus (HBRV) has been identified in humans, dating as far back as about 4500 years ago, with a high probability of it being acquired by our species around 10,000 years ago, following a species jump from mice to humans. HBRV is the human homolog of the MMTV (mouse mammary tumor virus), which is the etiological agent of murine mammary tumors. The hypothesis of a HMTV (human mammary tumor virus) was proposed about 50 years ago, and has acquired a solid scientific basis during the last 30 years, with the demonstration of a robust link with breast cancer and with PBC, primary biliary cholangitis. This article summarizes most of what is known about MMTV/HMTV/HBRV since the discovery of MMTV at the beginning of last century, to make evident both the quantity and the quality of the research supporting the existence of HBRV and its pathogenic role. Here, it is sufficient to mention that scientific evidence includes that viral sequences have been identified in breast-cancer samples in a worldwide distribution, that the complete proviral genome has been cloned from breast cancer and patients with PBC, and that saliva contains HBRV, as a possible route of inter-human infection. Controversies that have arisen concerning results obtained from human tissues, many of them outdated by new scientific evidence, are critically discussed and confuted.
Special Issue “Viral and Host Factors Driving the Emergence and the Evolution of the SARS-CoV-2 and Other Coronaviruses”
Authors: Ronfort Corinne
Published: August 2022

Two and half years ago, humanity was facing the emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causal agent of the COVID-19 pandemics that significantly impact public health, society and the global economy [...]
COVID-19 Vaccination in China: Adverse Effects and Its Impact on Health Care Working Decisions on Booster Dose
Authors: Luo Chengwen , Chen Hai-Xiao , Tung Tao-Hsin
Published: August 2022

Although many research studies have concentrated on people’s willingness to take the COVID-19 vaccine, little attention has been paid to the underlying mechanism of consent. An understanding of potential factors and mechanisms that affect the willingness to receive a vaccination can contribute information critical for containing the pandemic. This study explored the effects of post-vaccination adverse reactions on the willingness to take the booster dose and the role of decision regret. A self-administered online survey was carried out in Taizhou, China. Questionnaires were completed by 1085 healthcare workers (HCWs), 1054 (97.1%) of whom had completed two doses of the COVID-19 vaccine. Mediation analysis methodology was applied in this study. Our study showed that post-vaccination adverse reactions in HCWs could decrease their willingness to take the booster dose. Of note, HCWs who experienced adverse reactions after vaccination would be more likely to regret their previous vaccination decisions, which, in turn, further reduced their willingness to receive a booster shot. Decision regret mediated the relationship between adverse post-vaccination reactions and a willingness to take the booster dose. The findings implied inextricable relationships among post-vaccination adverse reactions, decision regret, and willingness to take the booster dose. It is suggested that notice of these post-vaccination adverse reactions should be further incorporated into vaccine communication campaigns and policy interventions advocating booster doses to improve vaccine uptake intent and increase the willingness to receive booster doses of a COVID-19 vaccine.
The Ring-Necked Pheasant (Phasianus colchicus) Industry within the United Kingdom and the Threat Posed by Mycoplasma gallisepticum: A Review
Authors: Balfour Matthew J.
Published: August 2022

In ring-necked pheasants (Phasianus colchicus), Mycoplasma gallisepticum (MG) infection is frequently associated with infectious sinusitis. This condition causes swelling of the infraorbital sinuses, upper respiratory distress, depression and variable levels of mortality, and is considered one of the most important clinical and economic diseases of pheasants. This review provides a brief overview of the structure of the UK pheasant industry, with reference to the various stages within the supply chain, common diseases and challenges facing the industry. The current understanding of MG transmission, prevalence, clinical expression, diagnosis and control strategies in pheasants is subsequently summarised. In addition, this review aims to assess the current gaps in knowledge relating specifically to MG in pheasants, with reference and extrapolation where appropriate to data gathered from other species.
The Italian Network of Laboratories for Veterinary Oncology (NILOV) 2.0: Improving Knowledge on Canine Tumours
Authors: Crescio Maria Ines , Ru Giuseppe , Aresu Luca , Bozzetta Elena , Cancedda Maria Giovanna , Capello Katia , Castagnaro Massimo , Carnio Azzurra , Cocumelli Cristiano , Degli Uberti Barbara , Eleni Claudia , Foiani Greta , Fonti Niccolò , Gibelli Lucia Rita , Maniscalco Lorella , Manuali Elisabetta , Moccia Valentina , Paciello Orlando , Petrella Antonio , Petrini Antonio , Poli Alessandro , Puleio Roberto , Razzuoli Elisabetta , Scaramozzino Paola , Varello Katia , Vascellari Marta , Zappulli Valentina , Ferrari Angelo ,   on behalf of NILOV
Published: August 2022

Advances in tumour research are crucial, and comparative oncology can improve the knowledge in several ways. Dogs are not only models of specific naturally occurring tumours but can also be sentinels of environmental exposures to carcinogens, as they share the same environment with their owners. The purpose of this work was to describe the data collected by The Italian Network of Laboratories for Veterinary Oncology in the first 9 years of activity (2013–2021) and to evaluate their potential epidemiological significance. Frequencies of tumour topographies and main morphologies in dogs were described, analysed and compared, calculating age-adjusted proportional morbidity ratios and considering several risk factors (breed, sex, period and region of residence). These observations allowed us to highlight differences not only in morphology and topography of some tumours but also to formulate hypotheses on the potential role of some risk factors, e.g., neutering/spaying or geographical location. In our opinion, the results of this case series confirm the importance of initiating and consolidating animal cancer registration initiatives that would facilitate the possibility of conducting multicentric collaborative studies to deepen the knowledge of the epidemiology of tumours in dogs from a comparative perspective.
Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan
Authors: Mukhamadieva Nurzhamal , Julanov Mardan , Zainettinova Dinara , Stefanik Vasyl , Nurzhumanova Zhanat , Mukataev Aitbek , Suychinov Anuarbek
Published: August 2022

In the present work, the prevalence, etiological factors and effective treatment scheme of mastitis in cows of dairy farms “Balke” and “Madi-R” in Eastern Kazakhstan were investigated. In total, 210 heads were investigated on two farms. The incidence of mastitis in cows on dairy farms is not the same in different years. Average clinical mastitis was detected in 35.4% of cows in 2016, 19.6% in 2017, 28.5% in 2018, and in 2019 in 16.4% of cows. The prevalence rates of subclinical mastitis by year had some differences. So, in 2016—36.5% of cows, then in 2017—21.5%, 2018—19.3% and in 2019—22.6%. In cows with udder inflammation, serum calcium 9.37 ± 0.15 mg/% with a range of 8.0 to 10.8 mg/%, phosphorus 3.58 ± 0.07 mg/% (3.0 to 4.3 mg/%), reserve alkalinity 363.46 ± 6.69 mg/% (320 to 440), carotene 0.49 ± 0.03 mg/% (0.220 to 0.988 mg/%), which are in the lower limit of physiological parameters. The drug “Dorob” was tested during the study of comparative effectiveness of treatment methods. The results of the study showed that this drug has anti-inflammatory, antimicrobial and stimulating healing actions. The treatment of the sick cows with catarrhal mastitis has shown that a total of 8 cows have recovered in the control group and 10 cows in the experimental group with the preparation “Dorob”. The period of recovery in the control group was 8.8 ± 0.39, and in the experimental group—6.2 ± 0.28 (p < 0.05). The drug does not contain antibiotics and hormonal preparations. The inclusion of the drug in the scheme of treatment allows for effectively treating inflammatory processes in the udder of cows and restoring their productivity with minimal cost of time and money.
Ovarian Neuroglial Choristoma in a Bitch
Authors: Brambilla Eleonora , Banco Barbara , Faverzani Stefano , Scarpa Paola , Pecile Alessandro , Groppetti Debora , Pigoli Claudio , Giraldi Marco , Grieco Valeria
Published: August 2022

Neuroglial choristomas are rare malformations consisting of heterotopic mature neural tissue at a site isolated from the brain or spinal cord. In human medicine, neuroglial choristomas are predominantly reported in the head and in the neck, except for one recent case reported in a foot of a child. In domestic animals, neuroglial choristomas are exceedingly rare, reported only in the retina of a dog, in the pharynx and in the skin of two kittens, and within the oropharynx of a harbor seal. A three-year-old intact female Jack Russell Terrier presented for elective ovariectomy exhibited a cystic lesion 2 cm in diameter expanding in the right ovary. Histological examination of the lesion revealed a mass composed of well-organized neuroglial tissue. Immunohistochemistry with primary antibodies against GFAP, NSE, and IBA-1 confirmed the neuroglial origin of the mass. At the time of this writing, 7 years after ovariectomy, the dog was clinically normal. Together with a recent case described in the foot of a child, this case confirms that neuroglial choristoma may also be found far from the skull or spine, supporting the hypothesis that they may arise from an early embryological migration defect.
Hand2os1 Regulates the Secretion of Progesterone in Mice Corpus Luteum
Authors: Jia Yanni , Liu Lu , Gong Suhua , Li Haijing , Zhang Xinyan , Zhang Ruixue , Wang Aihua , Jin Yaping , Lin Pengfei
Published: August 2022

The corpus luteum plays a key role in pregnancy maintenance and estrous cycle regulation by secreting progesterone. Hand2os1 is an lncRNA located upstream of Hand2, with which a bidirectional promoter is shared and is involved in the regulation of cardiac development and embryo implantation in mice. The aim of this study was to investigate the expression and regulation of Hand2os1 in the ovaries. Here, we used RNAscope to detect differential expression of Hand2os1 in the ovaries of cycling and pregnant mice. Hand2os1 was specifically detected in luteal cells during the proestrus and estrus phases, showing its highest expression in the corpus luteum at estrus. Additionally, Hand2os1 was strongly expressed in the corpus luteum on day 4 of pregnancy, but the positive signal progressively disappeared after day 8, was detected again on day 18, and gradually decreased after delivery. Hand2os1 significantly promoted the synthesis of progesterone and the expression of StAR and Cyp11a1. The decreased progesterone levels caused by Hand2os1 interference were rescued by the overexpression of StAR. Our findings suggest that Hand2os1 may regulate the secretion of progesterone in the mouse corpus luteum by affecting the key rate-limiting enzyme StAR, which may have an impact on the maintenance of pregnancy.
Assessment of Diffuse Pollution Loads in Peri-Urban Rivers—Analysis of the Accuracy of Estimation Based on Monthly Monitoring Data
Authors: Carvalho Daniela Junqueira , Costa Maria Elisa Leite , Koide Sergio
Published: August 2022

Diffuse pollution loads are crucial information for water resource management, and yet field data are often scarce, implying questionable accuracy in load estimates made from low-frequency water quality monitoring. This paper aimed to characterize diffuse pollution in a stream of a mixed-land-cover watershed with a significant portion of urbanized areas through intensive monitoring and to perform a comparative analysis between the loads estimated by pollutant rating curves obtained by regression and the estimates using monthly water quality data, which is the method currently used. Continuous rainfall and flow monitoring was conducted between 2019 and 2021, and samples were collected during flood events and the dry period for water quality analysis. Flood events were found to induce an increase in suspended solids (TSS) and COD concentrations, while inorganic nitrogen (Inorg-N) concentrations were higher in the dry season. Flood characteristics showed a positive correlation with solids and COD event mean concentrations (EMCs) and negative with Inorg-N EMCs, while rainfall characteristics, such as antecedent dry days and intensity, correlate positively with all these pollutants. The rating curves performed well for total load estimation in low discharge events (R2 and NSE > 0.8), except for total phosphorus (TP) loads. Estimated annual unit loads found for the watershed were 2 ton TSS/ha.year, 300 kg COD/ha.year, 5 kg Inorg-N/ha.year, and 0.5 kg TP/ha.year, showing high pollution generated in the watershed. Finally, a comparison with estimates based on monthly monitoring data indicated that this method is sufficient for accurate nutrient loads, but not for TSS and COD loads, which require continuous monitoring to improve the accuracy of estimation.
Estimation of Water Resource Ecosystem Service Value inTarim River Basin—From a Full Value Chain Perspective
Authors: Lu Quan , Hua Duo , Li Yanjun , Wang Dezhen
Published: August 2022

The estimation of ecosystem service value of water resources in the Tarim River Basin is of great significance for resource allocation management and ecological protection. However, there is still no unified and complete evaluation method for the ecosystem service value of inland rivers in China. Based on the perspective of the whole value chain, this study classified its ecological service functions and divided 11 sub-categories into four categories (supply, regulation, culture, and support) as evaluation indicators to carry out the quantitative evaluation. The results showed that the total value of ecosystem services in the Tarim River Basin in 2018 was USD 96.0262 billion (109), and the values of regulating function, cultural function, supporting function, and supply function were, successively from high to low, as follows: USD 38.7938 × 109, USD 36.7204 × 109, USD 19.6209 × 109, USD 0.8911 × 109, among which the value of regulation function was dominant.
Optimizing the Performance of Coupled 1D/2D Hydrodynamic Models for Early Warning of Flash Floods
Authors: Mitsopoulos Georgios , Panagiotatou Elpida , Sant Vasiliki , Baltas Evangelos , Diakakis Michalis , Lekkas Efthymios , Stamou Anastasios
Published: August 2022

We pose the following research question, “what are (i) the minimum required computation grid and (ii) the required form of hydrodynamic equations, i.e., shallow water equations (SWE) or diffusion wave equations (DWE), in 2D modeling to minimize the computational time while maintaining an acceptable level of error in the prediction of water depths and the extent of flood inundated areas?”. To answer this question, we apply the HEC-RAS 1D/2D model to simulate a disastrous flash flood in the town of Mandra, in Attica, Greece, in November 2017. HEC-RAS 1D/2D combines 1D modeling in the cross-sections of the two main streams of Mandra with 2D modeling in the rest of the potentially flooded area of the computational domain which has an area equal to 18.36 km2. We perform calculations for 8 scenarios that combined various grid sizes (with approximately 44,000–95,000 control volumes) with the use of the SWE or DWE. We derive the following conclusions: (i) calculated maximum water depths using DWE were equal to 60–65% of the corresponding water depths using SWE, i.e., the DWE significantly underestimated water depths; (ii) calculated total inundation areas using the SWE were approximately 4.9–7.9% larger than the corresponding inundation areas using the DWE; these differences can be considered as acceptable; and (iii) the total computation times using SWE, which ranged from 67 to 127 min, were 60–70% longer than the computation times using DWE.
Hydrologic and Cost–Benefit Analysis of Multiple Check Dams in Catchments of Ephemeral Streams, Rajasthan, India
Authors: Dashora Yogita , Cresswell David , Dillon Peter , Maheshwari Basant , Clark Richard , Soni Prahlad , Singh Pradeep Kumar
Published: August 2022

Investment in the small-scale enhancement of groundwater recharge through check dams and other recharge structures in rural India is on the order of USD 1 billion/year. However, for any catchment, the optimal capacity of check dams is unknown, and the impacts on downstream flows are rarely determined. This paper describes a method that can be applied to plan recharge augmentation in catchments that have at least one monitored check dam. It was applied in the Dharta catchment of the Aravalli Hills in Udaipur district, Rajasthan, India, where four check dams in an ephemeral stream were monitored by farmers over seven years. For the last three years of this study, the hydrology of two of these check dams was affected by 19 new check dams established upstream. A basic hydrologic model, WaterCress, was calibrated on monitored check-dam storages and used to assess the impacts of the new structures on recharge from those downstream. Then, the model was rerun with a range of capacities of upstream check dams to determine the effects of check-dam capacity on (1) the recharge from the downstream check dam, (2) the total recharge from all check dams, and (3) the frequency of spill from the downstream check dam. Using the available economic information, the benefit–cost ratio was calculated for a range of check-dam capacities. This showed a decline in economic efficiency with each new check dam and defined the optimal capacity. Monsoon size was found to be consequential to results, and longer hydrological records yield more reliable results. The study showed that monitoring check dams, rainfall, and groundwater levels is key to deciding whether additional check dams are economically beneficial.
Experimental Design of Nature-Based-Solution Considering the Interactions between Submerged Vegetation and Pile Group on the Structure of the River Flow on Sand Beds
Authors: Miyab Nazanin Mohammadzade , Fazloula Ramin , Heidarpour Manouchehr , Kavian Ataollah , Rodrigo-Comino Jesús
Published: August 2022

Designing correct engineering infrastructures to reduce land degradation processes and considering natural elements to achieve this goal are key to correctly managing potential natural hazards affecting human activities and natural ecosystems. This research investigated the scour depth and velocity vectors around bridge piles with and without upstream vegetation protection. A Doppler velocity meter was used to measure velocity components in a channel 90 cm wide, 16 m long, and 60 cm high. Variable parameters were the number of bridge piles, the height, density, and width of vegetation upstream, as well as the distance between bridge piles. Using a triple pile group with a distance between piles of 10 cm and overall vegetation across the channel, the depth of the scour hole upstream of the first pile decreased by 40% compared to the single pile with no vegetation. This result shows the significant impact of using vegetation and pile groups to reduce scour around piles. Lower vertical velocity gradients, more consistent velocity vectors, reducing the downstream flow range, and restraining horseshoe vortexes and wake vortices were observed in utilizing vegetation. We confirmed that vegetation is an essential factor in changing the flow, transportation of sediment, and conserving ecological services in rivers.
A River Channel Extraction Method Based on a Digital Elevation Model Retrieved from Satellite Imagery
Authors: Gui Rongjie , Song Wenlong , Pu Xiao , Lu Yizhu , Liu Changjun , Chen Long
Published: August 2022

The river border positioning is an important part of river surveys, which is crucial for water conservation project development, water resource use, water disasters, river regime monitoring, and many other applications related to water resources. Currently, satellite images or field measurements are used to extract river channels. However, satellite images are insufficiently precise, and field measurement requires significant manpower and cost. In this paper, a new method for river channel extraction is proposed, which is based on the combination of Jenks natural breaks classification method and digital elevation model (DEM), and then the river channel range is complemented by using the water range monitored by GF-1(Gaofen-1 satellite) in flood season. The overall precision is greater than 85%, and the Kappa values achieve moderate stability (0.41–0.60). Using this method, the extraction of river range is practicable and achievable, and the higher the DEM resolution, the better the extraction result.
Psychological consulting of patients with anxiety phenomena using the gestalt therapy method in the conditions of the open psychiatric hospital
Authors:   Research and Clinical Center for Neuropsychiatry of Moscow Healthcare Department, Meshandin I. A. , Teterina M. N. ,   Research and Clinical Center for Neuropsychiatry of Moscow Healthcare Department
Published: August 2022

The main principals of the psychological consultation of the patients with the anxious phenomenons with the use of gestalt therapy are outlined in this article. The main therapeutic principals of this method are described. The work is done in the Research and Clinical Center for Neuropsychiatry of Moscow Healthcare Department.
Differential diagnosis of secondary parkinsonism in a complex clinical case in the city of Vladikavkaz
Authors:   Department of Psychiatry with Neurology, Neurosurgery and Medical Rehabilitation, FSBEI HE «NOSMA» Vladikavkaz, Kumakhov A. A. , Tambiev A. R. ,   Department of Neurology, Psychiatry and Narcology, Faculty of Medicine, FSBEI HE «KBSU named after H. M. Berbekov» Nalchik, Keisinova A. R. ,   Department of Neurology, Psychiatry and Narcology, Faculty of Medicine, FSBEI HE «KBSU named after H. M. Berbekov» Nalchik, Karsanov T. D ,   Department of Psychiatry with Neurology, Neurosurgery and Medical Rehabilitation, FSBEI HE «NOSMA» Vladikavkaz
Published: August 2022

This article describes the differential diagnosis of secondary parkinsonism in a complex clinical example. Information about the patient was collected at a neurologist's appointment by collecting complaints, an anamnesis of life and disease, conducting a thorough general and neurological examination, and conducting additional diagnostic methods. After studying the obtained clinical data of the patient, a differential diagnosis was made between vascular and drug-induced parkinsonism. The factors and influencing each of these diagnoses are determined. The most likely diagnosis was successfully made, followed by appropriate therapy. This article also shows clinical experience on secondary types of parkinsonism, which will be very useful for neurologists at all levels of medical care.
The role of the venous system in the maintenance of cerebral perfusion pressure in acute ischemic stroke
Authors:   North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russia, Lobzin V. Yu. ,   Scientific and Clinical Center for Infectious Diseases of the FMBA of Russia,   S.M. Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation, St. Petersburg, Nikiforova L. G. ,   North-Western State Medical University named after I. I. Mechnikov of the Ministry of Health of Russia, St. Petersburg I. I. Dzhanelidze Research Institute for Emergency Medicine
Published: August 2022

The article analyzes the state of cerebral venous hemodynamics in the acute period of ischemic stroke based on the results of clinical neurological, Dopplerographic, neuroimaging and cerebrospinal fluid examination of patients with different amounts of brain matter damage. Factors for predicting the development of moderate or severe cerebral venous dyscirculation have been identified. Attention is paid to the importance of a comprehensive examination of patients with assessment of cerebral venous blood flow in the acute period of ischemic stroke.
Past 7th All-Russian Congress of Manual Medicine
Authors:   Pavlov First St. Petersburg State Medical University, Andreev V.V. , Akhmetsafin A.N. ,   Pavlov First St. Petersburg State Medical University, Barantsevich E.R. ,   Pavlov First St. Petersburg State Medical University, Egorova I.N. ,   Yaroslav-the-Wise Novgorod State University, Mokhov D.E. ,   North-Western State Medical University named after I.I. Mechnikov; Saint Petersburg State University, Institute of Osteopathy., Novoseltsev S.V. ,   private ANO DPO North-Western Academy of Osteopathy and Medical Psychology, St. Petersburg, Russia; FGAOU VO I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow, Russia, Samorukov A.E. ,   FSBI "National Medical Research Center for Rehabilitation and Balneology" of the Ministry of Health of the Russian Federation, Skoromets A.A. ,   Pavlov First St. Petersburg State Medical University
Published: August 2022

The All-Russian Congress of Manual Medicine has been held in St. Petersburg in April 8-10, 2022. The thematic scientific forum has been held in accordance with the charter of the All-Russian Association of Manual Medicine and has been dedicated to the most important dates in Russian medicine. The Congress has celebrated the 100th anniversary of the birth of Viola Fraiman, the founder of osteopathy in the Russian Federation, and the 85th anniversary of Aleksandr Anisimovich Skoromets, head of the Department of Neurology, Pavlov First Saint-Petersburg State Medical University, honorary president of the All-Russian Association of Manual Medicine, member of the Russian Academy of Sciences.
Financial Instruments accounting: innovations, problems, solutions
Authors:   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhni Novgorod”, Nizhny Novgorod, Russia, Druzhilovskaya T.Y.
Published: August 2022

Recently, the importance of such objects as financial instruments has increased in the activities of Russian organizations of various forms of ownership and various industries (including healthcare). This necessitates a realistic accounting of these objects. In turn, for the implementation of realistic accounting, carefully developed rules are required, which are laid down in regulatory documents on accounting. In the system of international financial reporting standards (IFRS) there are a number of standards containing regulations for the accounting of financial instruments. Despite the fact that the Russian system of accounting standards (RAS) has long been in the process of being reformed based on international standards, the area of accounting for financial instruments is still not sufficiently regulated. At the same time, the program for the development of Russian federal accounting standards (FSBU) involves a number of changes in existing regulatory accounting documents, as well as the creation of new accounting standards. In this regard, it is of interest to analyze the FSBU Project “Financial Instruments” presented for discussion, developed by the Accounting Development Fund “National Non-State Accounting Regulator “Accounting Methodological Center” (Foundation “NRBU “BMC”). The study of the regulations of this FSBU “Financial Instruments” Project is carried out in this article. The research methods were comparison, analysis, synthesis, grouping method, systemic and logical approaches. As a result of the study, the article substantiates the positive aspects of the FSBU “Financial Instruments” Project, identifies some of its shortcomings, substantiates the value of this regulatory document for realizing the goal of reliable accounting of financial instruments.
Moratorium on health checks: myth or reality?
Authors:   Plekhanov Russian University of Economics, Moscow, Russia, Кovalenko S.N. , Kovalenko Y.N. ,   Plekhanov Russian University of Economics, Moscow, Russia
Published: August 2022

In this article, the authors focus on the concept of a moratorium, establish regulations defining and regulating the procedure for compliance with these actions. It describes the introduction of additional requirements for the activities of medical institutions, certain conditions for the organization of internal quality control and safety of medical activities, as well as provisions for the training of medical personnel. Among other things, the issues of a moratorium on carrying out control measures of a planned nature in relation to healthcare institutions are being investigated. The authors also consider the issue of approaches to compliance with the Decree of the Government of the Russian Federation No. 336 of10.03.2022 by Roszdravnadzor of the Russian Federation for the period 2022. Moreover, the measures of internal quality control and safety of activities within the framework of the moratorium on external scheduled inspections for the period 2022 in relation to medical institutions are presented, the tasks of the measures being implemented are defined.
Information support of the procurement process in medical institutions
Authors:   Plekhanov Russian University of Economics, Moscow, Russia, Danchikov E.A. , Kovalenko Y.N. ,   Plekhanov Russian University of Economics, Moscow, Russia, Kovalenko S.N. ,   Plekhanov Russian University of Economics, Moscow, Russia
Published: August 2022

This article discusses the legislative and regulatory framework for the implementation of the procurement process. The possibilities of public procurement by medical institutions are being investigated. The procedure for determining the initial maximum contract price (NMCC) is evaluated. The total volume of purchases of a particular medical institution for the period of participation in procurement activities, as well as the structure of contracts concluded, is presented. The basic information approaches to public procurement in medical institutions are being formed. The object of purchase of a specific medical institution is described. The contracts concluded with the supplier for the supply of goods, works, services are evaluated from the point of view of compliance with all established norms and requirements.
Approaches to integrated disclosure of capital information in the context of sustainable development of agricultural formations
Authors:   Federal State Budgetary Educational Institution of Higher Education «Kuban State Agrarian University named after I.T. Trubilin», Krasnodar, Russia, Pilyuk R. A.
Published: August 2022

The evaluates of the published non-financial information by joint-stock companies of the agricultural sector of the Krasnodar region economy was performed in the article. The problems of forming reliable, complete, comparable, verifiable non-financial information about the state and changes in all components of capital from the point of view of sustainable development of agricultural formations were revealed. The roadmap has been formed for the regulation of non-financial reporting in the Russian Federation. The concept of optimal integrated disclosure of information on sustainable development has been developed.
Factores que inciden en la calificación que los docentes asignan a los alumnos
Authors: Pérez García José , López Ortega María de los Ángeles
Published: August 2022

El propósito de este artículo fue determinar cuáles son las prácticas de evaluación que sustentan la calificación asignada por los profesores a los alumnos y que tan válida y confiable es la información que sustenta la calificación. Se utilizó como metodología el análisis documental para identificar la literatura especializada sobre los factores que influyen en la calificación que los profesores asignan a los alumnos. Se analizaron 27 estudios y se encontró predominio de prácticas no alineadas a los programas de estudio, calificaciones basadas en una mezcla de factores cognitivos y no cognitivos y ausencia de formación en evaluación. Se concluye que es cuestionable la confiabilidad y validez de las calificaciones asignadas por los profesores, es necesario fortalecer la literacidad en evaluación de los docentes y directivos escolares, entrenamiento en prácticas de calificación efectivas y promover la evaluación formativa.
Development of New Equations Predicting the Mortality Risk of Patients on Continuous RRT
Authors: Kang Min Woo , Tangri Navdeep , Kwon Soie , Li Lilin , Lee Hyeseung , Han Seung Seok , An Jung Nam , Lee Jeonghwan , Kim Dong Ki , Lim Chun Soo , Kim Yon Su , Kim Sejoong , Lee Jung Pyo ,   on behalf of the VENUS trial Investigators
Published: August 2022

Key Points

Predicting the risk of mortality in patients with CRRT is important for appropriate management, but is challenging.

We developed equations for predicting the mortality risk of patients with CRRT, using patients’ clinical data.

The newly developed equations showed superior performance to SOFA and APACHE II scores.

Background

Predicting the risk of death in patients admitted to the critical care unit facilitates appropriate management. In particular, among patients who are critically ill, patients with continuous RRT (CRRT) have high mortality, and predicting the mortality risk of these patients is difficult. The purpose of this study was to develop models for predicting the mortality risk of patients on CRRT and to validate the models externally.

Methods

A total of 699 adult patients with CRRT who participated in the VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT (VENUS) trial and 1515 adult patients with CRRT in Seoul National University Hospital were selected as the development and validation cohorts, respectively. Using 11 predictor variables selected by the Cox proportional hazards model and clinical importance, equations predicting mortality within 7, 14, and 28 days were developed with development cohort data.

Results

The equation using 11 variables had area under the time-dependent receiver operating characteristic curve (AUROC) values of 0.75, 0.74, and 0.73 for predicting 7-, 14-, and 28-day mortality, respectively. All equations had significantly higher AUROCs than the Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation II (APACHE II) scores. The 11-variable equation was superior to the SOFA and APACHE II scores in the integrated discrimination index and net reclassification improvement analyses.

Conclusions

The newly developed equations for predicting CRRT patient mortality showed superior performance to the previous scoring systems, and they can help physicians manage patients.
Reseña de: Crónicas y relaciones sobre el antiguo Tucumán Siglo XVI: Córdoba, La Rioja, Santiago del Estero, Tucumán, Catamarca, Salta, Jujuy: documentos y estudios críticos, de Eduardo Berberián y Beatriz Bixio (2017).
Authors: Huespe Tomá Maria Inés
Published: August 2022

La obra de Eduardo Berberián y Beatriz Bixio es un valioso aporte a los estudios sobre la conformación del Tucumán colonial. El objetivo es realizar una compilación de los segmentos más representativos de las crónicas, los informes oficiales y las relaciones de distinto orden relativas al descubrimiento y primeras fundaciones en el Tucumán en el siglo XVI. La intención de los autores es facilitar a los investigadores documentos de escasa accesibilidad o cuyas publicaciones están agotadas. Estos registros del pasado ofrecen información sobre los proyectos de conquista y colonización, los territorios, los grupos indígenas y los variados actores que poblaron las fronteras en esta región.
Sucesión cacical y estrategias políticas en Santa Isabel de Pucará (Corregimiento de Cabana y Cabanilla), Audiencia de Charcas, siglos XVI-XVII
Authors: Morrone Ariel  J.
Published: August 2022

Este artículo recupera los planteos de Martha Bechis sobre la sucesión cacical entre los rankülchen del sur de la actual provincia de Córdoba (Argentina) a mediados del siglo XIX, para considerar el mismo problema en los pueblos de reducción del sur andino entre finales del siglo XVI y principios del siglo XVII. Evaluamos la operatividad hermenéutica del concepto de “sucesión adélfica”, referido a una pauta hereditaria colateral o “entre hermanos”, para analizar las transformaciones operadas por el dominio colonial hispánico sobre los grupos nativos y sobre los criterios de legitimidad de los kuraka prehispánicos devenidos caciques principales. Nutridos por esta exploración sobre espacialidades y temporalidades discontinuas, hacemos foco en el pueblo de Santa Isabel de Pucará -corregimiento de Cabana y Cabanilla, actual departamento de Puno,Perú- para examinar los cambios en las pautas sucesorias a través del prisma de un pleito sucesorio de 1591-1606.
“Desde que se meció tu cuna, fuiste valiente”. El liderazgo mapuche en el contexto post-conquista, fines del siglo XIX y principios del XX
Authors: Delrio Walter
Published: August 2022

En este artículo me referiré a algunas de las líneas que la obra de Martha Bechis abrió en el campo de los estudios sobre la política y el liderazgo en las llamadas fronteras del Cono Sur americano. Su trabajo aportó al campo de los estudios históricos sobre los pueblos originarios de las Pampas, Araucanía y Patagonia un gran legado en cuanto a conceptos, temáticas y marcos de interpretación. Específicamente nos preguntamos sobre las implicancias y alcances que la propuesta de esta autora ha tenido para el abordaje de los procesos de sometimiento e incorporación estatal de los pueblos originarios desde fines del siglo XIX y durante el siglo XX en norpatagonia.
Los comechingones en Córdoba. Una mirada histórica sobre los procesos de invisibilización indígena (siglos XVI-XXI)
Authors: Sosnowski Daniela
Published: August 2022

En un contexto actual en el que se están desarrollando procesos de reemergencia indígena en la provincia de Córdoba, este trabajo se propone indagar en las representaciones hegemónicas acerca de los comechingones en un registro de muy larga duración. En ese sentido, se identifican tres períodos o momentos históricos en los que se desplegaron diversas concepciones dominantes acerca de lo indígena -y específicamente lo comechingón-: la época de la conquista, en la que se impuso el rótulo étnico como una forma de homogeneizar a los diversos pueblos que habitaban en la región; el siglo XIX, momento en elque se buscó invisibilizar todo rastro de lo indígena en la nueva nación que se estaba gestando; y finalmente el siglo XX, cuando desde la antropología clásica y la historiografía se recuperó el pasado de los pueblos prehispánicos pero negando nuevamente su presente y su futuro.