bluuebunny/crossref_metadata_2025 huggingface dataset:
Reduction of the Host Cationic Framework Charge by Isoelectronic Substitution: Synthesis and Structure of Hg7Ag2P8X6 (X: Br, I) and Hg6Ag4P8Br6.
Authors: Oleneva Olga S. , Olenev Andrei V. , Shestimerova Tatiana A. , Baranov Alexey I. , Dikarev Evgeny V. , Shevelkov Andrei V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Acid Zeolites as Alcohol Racemization Catalysts: Screening and Application in Biphasic Dynamic Kinetic Resolution.
Authors: Wuyts S. , De Temmerman K. , De Vos D. E. , Jacobs P. A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tuneable Asymmetric Copper‐Catalyzed Allylic Amination and Oxidation Reactions.
Authors: Clark J. Stephen , Roche Caroline
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Versatile Organocatalyst for the Asymmetric Conjugate Addition of Nitroalkanes to Enones.
Authors: Mitchell Claire E. T. , Brenner Stacey E. , Ley Steven V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Terpene Auxiliaries. Part 1. Highly Enantioselective Reduction of Ketones with Borane Catalyzed by an Oxazaborolidine Derived from (‐)‐β‐Pinene.
Authors: Krzeminski Marek P. , Wojtczak Andrzej
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Zirconium Catalysts Using Multidentate BINOL Derivatives for Catalytic Enantioselective Mannich‐Type Reactions; Ligand Optimization and Approaches to Elucidation of the Catalyst Structure.
Authors: Ihori Yoichi , Yamashita Yasuhiro , Ishitani Haruro , Kobayashi Shu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemo‐ and Regioselective Intermolecular Cyclotrimerization of Terminal Alkynes Catalyzed by Cationic Rhodium(I)/Modified BINAP Complexes: Application of One‐Step Synthesis of Paracyclophanes.
Authors: Tanaka Ken , Toyoda Kazuki , Wada Azusa , Shirasaka Kaori , Hirano Masao
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbon Tetrabromide: An Efficient Catalyst for Regioselective Ring Opening of Epoxides with Alcohols and Water.
Authors: Yadav J. S. , Reddy B. V. S. , Harikishan K. , Madan Ch. , Narsaiah A. V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Zirconium Hydroxide Chromate (Zr4(OH)6(CrO4)5 (H2O)2): A Mild and Efficient Reagent for Oxidation of Benzylic Alcohols.
Authors: Rahimizadeh M. , Hassani H. , Bakavoli M. , Gholizadeh M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A General Study of Aryloxo and Alkoxo Ligands in the Titanium‐Catalyzed Intermolecular Hydroamination of Terminal Alkynes.
Authors: Tillack Annegret , Khedkar Vivek , Jiao Haijun , Beller Matthias
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Zn/[bmim]PF6‐Mediated Markovnikov Allylation of Unactivated Terminal Alkynes.
Authors: Yadav J. S. , Reddy B. V. S. , Reddy P. Murali Krishna , Gupta Manoj K.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Wittig Reaction of a Series of Diazodiketones: Synthesis and Structure of Fluorine‐Containing Vinyldiazoketones.
Authors: Zakharova Valerija M. , Hennig Lothar , Nikolaev Valerij A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rh(I)‐Catalyzed Cleavage of Unactivated C—O Bonds — Carbonylative Rearrangement Reactions of Allenyl Ethers to 2‐Carboalkoxy‐1,3‐dienes.
Authors: Wender Paul A. , Deschamps Nicole M. , Sun Robert
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper(II) Tetrafluoroborate as a Novel and Highly Efficient Catalyst for Acetal Formation.
Authors: Kumar Raj , Chakraborti Asit K.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemoselective Deprotection of Thioacetals/Thioketals Using HIO3 in the Presence of Wet SiO2 under Mild Solvent‐Free Conditions.
Authors: Lakouraj Moslem M. , Tajbakhsh Mahmood , Shirini Farhad , Tamami Mohammad V. Asady
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Metal‐Catalyzed Multicomponent Syntheses of Secondary Propargylamides and Oxazoles from Silylimines, Acid Chlorides, and Alkynes.
Authors: Black Daniel A. , Arndtsen Bruce A
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Multivalent, Bifunctional Dendrimers Prepared by Click Chemistry
Authors: Wu Peng , Malkoch Michael , Hunt Jasmine N. , Vestberg Robert , Kaltgrad Eiton , Finn M. G. , Fokin Valery V. , Sharpless K. Barry , Hawker Craig J.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Difluoroallenyl Bromide as a Wide‐Ranging Difluoromethylene Cation Equivalent: SN2 Substitution of Difluoropropargyl Bromide Through Sequential SE2′ and SN2′ Reactions.
Authors: Xu Bo , Hammond Gerald B.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Improved Synthesis of Isonitrosoacetanilides.
Authors: Rewcastle Gordon W. , Sutherland Hamish S. , Weir Claudette A. , Blackburn Adrian G. , Denny William A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lewis Acid Assisted Cross Metathesis of Acrylonitrile with Functionalized Olefins Catalyzed by Phosphine‐Free Ruthenium Carbene Complex.
Authors: Bai Chen‐Xi , Lu Xiao‐Bing , He Ren , Zhang Wen‐Zhen , Feng Xiu‐Juan
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ruthenium‐Catalyzed Synthesis of Alkylidenecyclobutenes via Head‐to‐Head Dimerization of Propargylic Alcohols and Cyclobutadiene—Ruthenium Intermediates.
Authors: Le Paih Jacques , Derien Sylvie , Demerseman Bernard , Bruneau Christian , Dixneuf Pierre H. , Toupet Loic , Dazinger Georg , Kirchner Karl
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
C—C Bond Activation by Octacarbonyldicobalt: [3 + 1] Cocyclizations of Methylenecyclopropanes with Carbon Monoxide.
Authors: Kurahashi Takuya , de Meijere Armin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Structure of Diisopropyl 6‐Hydroxy‐6‐methyl‐4‐oxocyclohexane‐1,3‐dicarboxylate and Their Reactions with Nucleophilic Reagents.
Authors: Gein V. L. , Nosova N. V. , Potemkin K. D. , Aliev Z. G. , Kriven'ko A. P.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ag/SiO2: A Novel Catalyst with High Activity and Selectivity for Hydrogenation of Chloronitrobenzenes.
Authors: Chen Yangying , Wang Chuang , Liu Hongyang , Qiu Jieshan , Bao Xinhe
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Addition of Vinylzinc Reagents to Aldehydes Catalyzed by Modular Ligands Derived from Amino Acids.
Authors: Richmond Meaghan L. , Sprout Christopher M. , Seto Christopher T.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic, Asymmetric Aza‐Baylis—Hillman Reaction of N‐Sulfonated Imines with Activated Olefins by Quinidine‐Derived Chiral Amines.
Authors: Shi Min , Xu Yong‐Mei , Shi Yong‐Ling
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
P‐Chiral o‐Phosphinophenol as a P/O Hybrid Ligand: Preparation and Use in Cu‐Catalyzed Asymmetric Conjugate Addition of Diethylzinc to Acyclic Enones.
Authors: Takahashi Yukitoshi , Yamamoto Yoshikazu , Katagiri Kosuke , Danjo Hiroshi , Yamaguchi Kentaro , Imamoto Tsuneo
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Wittig—Horner Approach for the Synthesis of Tamoxifen (V).
Authors: Pandey Rajesh K. , Wakharkar R. D. , Kumar Pradeep
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Copper Triflate‐Catalyzed Cross‐Aldol Condensation: A Facile Synthesis of α,α′‐Bis(substituted benzylidene) Cycloalkanones.
Authors: Li Jianjun , Su Weike , Li Ning
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Lactones. Part 18. Synthesis of Bicyclic Lactones with Methyl‐, Di‐ and Trimethyl Substituted Cyclohexane System.
Authors: Grabarczyk M. , Szumny A. , Gladkowski W. , Bialonska A. , Ciunik Z. , Wawrzenczyk C.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Photochromic Dihetarylethylenes. Part 22. Synthesis and Photochromic Properties of Unsymmetrical Alkylthio‐Substituted 1,2‐Bis(dithienyl)perfluorocyclopentenes.
Authors: Krayushkin M. M. , Kalik M. A. , Kozhinov D. V. , Martynkin A. Yu.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electrophile‐Induced Ring Expansions of β‐Lactams Toward γ‐Lactams.
Authors: Van Brabandt Willem , De Kimpe Norbert
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Supramolecular Click Chemistry for the Self‐Assembly of a Stable Zn(II)—Porphyrin—C60 Conjugate.
Authors: Trabolsi Ali , Elhabiri Mourad , Urbani Maxence , Delgado de la Cruz Juan Luis , Ajamaa Fettah , Solladie Nathalie , Albrecht‐Gary Anne‐Marie , Nierengarten Jean‐Francois
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Indole‐2‐carboxamidines as Novel NR2B Selective NMDA Receptor Antagonists.
Authors: Borza Istvan , Kolok Sandor , Ignacz‐Szendrei Gyoergyi , Greiner Istvan , Tarkanyi Gabor , Galgoczy Kornel , Horvath Csilla , Farkas Sandor , Domany Gyoergy
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Furan Ring Opening—Indole Ring Closure: Pseudooxidative Furan Ring Opening in the Synthesis of Indoles.
Authors: Butin Alexander V. , Smirnov Sergey K.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Facile and Efficient Synthesis of Enyne‐Reaction Precursors by Multicomponent Reactions.
Authors: Struebing Dirk , Neumann Helfried , Klaus Stefan , Huebner Sandra , Beller Matthias
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Direct Single Step Synthesis of 1,3‐Diaryl‐4‐cyanopyrazoles and Their Conversion to 1,3‐Diaryl‐4‐(4,6‐diamino‐1,3,5‐triazin‐2‐yl)pyrazoles.
Authors: Reddy G. Jagath , Manjula D. , Rao K. Srinivasa
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Substituted Ethyl 1,2,3,4,4′,5′‐Hexahydrospiro[naphthalene‐2,5′‐pyrazole]‐3′‐carboxylates with Halogens.
Authors: Molchanov A. P. , Korotkov V. S. , Kopf J. , Kostikov R. R.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Estrogen Receptor β Selective Ligands: Discovery and SAR of Novel Heterocyclic Ligands.
Authors: Chesworth Richard , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Benzimidazole‐5‐sulfonamides as Novel Nonpeptide Luteinizing Hormone Releasing Hormone (LHRH) Antagonists: Minimization of Mechanism‐Based CYP3A4 Inhibition.
Authors: Hashimoto Kentaro , Kataoka Mikayo , Tatsuta Miyuki , Yasoshima Kayo , Yamamoto Mako , Yura Takeshi , Yamamoto Noriyuki , Urbahns Klaus , Gupta Jang Bahadur , Li Yingfu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Alkoxyphthalimide Derivatives of 5‐Arylidene‐2‐(6′‐chlorobenzothiazol‐2′‐yl‐imino)‐4‐thiazolidinones.
Authors: Dixit N. , Talesara G. L.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium—Copper Catalyzed Heteroannulation of Acetylenic Compounds: An Expeditious Synthesis of Isoindoline Fused with Triazoles.
Authors: Chowdhury Chinmay , Mandal Sukhendu B. , Achari Basudeb
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Furan Ring Opening—Isochromene Ring Closure: A New Approach to Isochromene Ring Synthesis.
Authors: Butin Alexander V. , Abaev Valdimir T. , Mel'chin Vladimir V. , Dmitriev Artem S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sulfamic Acid: A Novel and Efficient Catalyst for the Synthesis of Aryl‐14H‐dibenzo[a.j]xanthenes under Conventional Heating and Microwave Irradiation.
Authors: Rajitha B. , Kumar B. Sunil , Reddy Y. Thirupathi , Reddy P. Narsimha , Sreenivasulu N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Condensation of Sulfur Containing Pyridine Systems. Part 2. Synthesis and Methylation of Triethylammonium 1‐Cyano‐4,5‐dioxo‐3,4,5,6‐tetrahydro[1]benzopyrano [3,4‐c]pyridine‐2‐thiolate (IV).
Authors: Dotsenko V. V. , Krivokolysko S. G. , Litvinov V. P.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Interaction of 4,5,7‐Trimethyl‐4,5,6,7‐tetrahydropyrrolo[3,2‐c]pyridines with Acetic and Trifluoroacetic Anhydrides.
Authors: Borisova T. N. , Voskressensky L. G. , Soklakova T. A. , Chernyshev A. I. , Bonifas Nsabimana , Borisov R. S. , Varlamov A. V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Unusual Reaction of (2‐Oxo‐1,2‐dihydro‐3H‐indol‐3‐ylidene)acetic Acid Esters with Hydrazine.
Authors: Kozminykh V. O. , Lomidze K. Sh. , Goncharov V. I. , Aksenov A. V. , Kozminykh E. N. , Berezin A. N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antimicrobial Activity of 5‐Hydroxymethyl‐8‐methyl‐2‐(N‐arylimino)‐pyrano [2,3‐c]pyridine‐3‐(N‐aryl)‐carboxamides.
Authors: Zhuravel' Irina O. , Kovalenko Sergiy M. , Ivachtchenko Alexandre V. , Balakin Konstantin V. , Kazmirchuk Victor V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of New Chiral 6‐Carbonyl 2,3,8,8a‐Tetrahydro‐7H‐oxazolo[3,2‐a]pyridines.
Authors: Noel Romain , Vanucci‐Bacque Corinne , Fargeau‐Bellassoued Marie‐Claude , Lhommet Gerard
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Molluscicidal Activity of 6‐Carboethoxy‐(2‐substituted)‐1,3,4‐thia/oxadiazolo [2,3‐b]pyrimidin‐5‐ones and 5‐Amino‐(2‐substituted)‐1,3,4‐thia/oxadiazolo[2,3‐b]pyrimidin‐7‐ones.
Authors: Singh Ashutosh , Nizamuddin Nizamuddin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Heterocyclic Analogues of 4‐(2‐Chloro‐5‐methoxyanilino)quinazolines as Potent and Selective c‐Src Kinase Inhibitors.
Authors: Barlaam Bernard , Fennell Mike , Germain Herve , Green Tim , Hennequin Laurent , Morgentin Remy , Olivier Annie , Ple Patrick , Vautier Michel , Costello Gerard
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
(2,3‐Dibromopropyl)sulfonylarenes in S,N‐Tandem Heterocyclizations. A New Synthesis of Thiazolopyrimidines.
Authors: Shklyarenko A. A. , Chernitsa B. V. , Yakovlev V. V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Regioselective Synthesis of 3‐Benzylthiazolo[3,2‐a]pyrimidones and 3‐Benzyl‐thiazolo[3,2‐c]pyrimidones Through Palladium‐Catalyzed Heteroannulation of Acetylenic Compounds.
Authors: Heravi Majid M. , Kivanloo Ali , Rahimizadeh Mohammad , Bakavoli Mehdi , Ghassemzadeh Mitra , Neumueller Bernhard
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and in vitro Antihepatitis B and C Virus Activities of Ring‐Expanded (“Fat”) Nucleobase Analogues Containing the Imidazo[4,5‐e][1,3]diazepine‐4,8‐dione Ring System.
Authors: Zhang Peng , Zhang Ning , Korba Brent E. , Hosmane Ramachandra S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Evaluation of Novel 8,6‐Fused Bicyclic Peptidomimetic Compounds as Interleukin‐1β Converting Enzyme Inhibitors.
Authors: O'Neil Steven V. , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ketene Aminal‐Based Lactam Derivatives as a Novel Class of Orally Active FXa Inhibitors.
Authors: Shi Yan , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Activity of N‐Acyl Azacyclic Urea HIV‐1 Protease Inhibitors with High Potency Against Multiple Drug Resistant Viral Strains.
Authors: Zhao Chen , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of Allyl Phenylcarbamate with 5‐Methyl‐4,5‐dihydro‐3H‐2‐benzazepine‐3‐spirocyclohexan N‐Oxide.
Authors: Velikorodov A. V. , Zubkov F. I. , Kovalev V. B.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Intramolecular Carbonylation Reactions with Recyclable Palladium‐Complexed Dendrimers on Silica: Synthesis of Oxygen, Nitrogen, or Sulfur‐Containing Medium Ring Fused Heterocycles.
Authors: Lu Shui‐Ming , Alper Howard
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Photoisomerization as a Trigger for Bergman Cyclization: Synthesis and Reactivity of Azoenediynes.
Authors: Kar Moumita , Basak Amit , Bhattacharjee Manish
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Transformation of [Difluoro(phenylseleno)methyl]trimethylsilane.
Authors: Qin Ying‐Ying , Qiu Xiao‐Long , Yang Yan‐Yan , Meng Wei‐Dong , Qing Feng‐Ling
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Limbatolide F and G: Two New trans‐Clerodane Diterpenoids from Otostegia limbata.
Authors: Farooq U. , Khan A. , Ahmad V. U. , Kousar F. , Iqbal S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
C,O‐Nitration of 17β‐Acetoxy‐17α‐ethynylestra‐1,3,5 (10)‐triene‐3,11α‐diol.
Authors: Golubovskaya L. E. , Rzheznikov V. M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
(S,S)‐(+)‐Pseudoephedrine as Chiral Auxiliary in Asymmetric Aza‐Michael Reactions. Unexpected Selectivity Change when Manipulating the Structure of the Auxiliary.
Authors: Etxebarria Juan , Vicario Jose L. , Badia Dolores , Carrillo Luisa , Ruiz Nerea
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses of (S)‐Enantiomers of Hanishin (Ia), Longamide B (Ib), and Longamide B Methyl Ester (Ic) from L‐Aspartic Acid β‐Methyl Ester: Establishment of Absolute Stereochemistry.
Authors: Patel Jignesh , Pelloux‐Leon Nadia , Minassian Frederic , Vallee Yannick
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isolation and Synthesis of a New Aromatic Compound, Brefelamide, from Dictyostelium Cellular Slime Molds and Its Inhibitory Effect on the Proliferation of Astrocytoma Cells.
Authors: Kikuchi Haruhisa , Saito Yoshinori , Sekiya Jun'ichi , Okano Yumiko , Saito Masaki , Nakahata Norimichi , Kubohara Yuzuru , Oshima Yoshiteru
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Prostanoids. Part 90. Extension to the Synthesis of Enprostil via the o‐Nitrophenylsulfonylhydrazine Method for Transformation of 2‐Propynyl Alcohols into Allenes.
Authors: Vostrikov N. S. , Vasikov V. Z. , Miftakhov M. S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Merging Homogeneous Catalysis with Biocatalysis; Papain as Hydrogenation Catalyst.
Authors: Panella Lavinia , Broos Jaap , Jin Jianfeng , Fraaije Marco W. , Janssen Dick B. , Jeronimus‐Stratingh Margot , Feringa Ben L. , Minnaard Adriaan J. , de Vries Johannes G.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Method for Synthesis of Angucyclinone Antibiotics via Gold‐Catalyzed Intramolecular [4 + 2] Benzannulation: Enantioselective Total Synthesis of (+)‐Ochromycinone (Ia) and (+)‐Rubiginone B2 (Ib).
Authors: Sato Kenichiro , Asao Naoki , Yamamoto Yoshinori
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Brief and Convergent Synthetic Route to Defucogilvocarcin M (I) Chromophore: The Formal Synthesis of WS‐5995 A (II) and C (III).
Authors: Patra Asit , Pahari Pallab , Ray Sutapa , Mal Dipakranjan
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
FR177391, a New anti‐Hyperlipidemic Agent from Serratia. Part 2. Pharmacological Activity of FR177391.
Authors: Inami Masamichi , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
FR177391, a New anti‐Hyperlipidemic Agent from Serratia. Part 4. Target Identification and Validation by Chemical Genetic Approaches.
Authors: Yamaoka Makiko , Sato Kentaro , Kobayashi Motoo , Nishio Nobuya , Ohkubo Mitsuru , Fujii Takashi , Nakajima Hidenori
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transformation of Nanoporous Oxoselenoantimonates into Sb2O3—Nanoribbons and Nanorods.
Authors: Sendor Dorota , Weirich Thomas , Simon Ulrich
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ordered Alignment of CdS Nanocrystals on MWCNTs Without Surface Modification.
Authors: Liu Bin , Lee Jim Yang
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Promising Avenues of Research in Nanoscience: Chemistry of Semiconductor Nanoparticles
Authors: Gubin S. P. , Kataeva N. A. , Khomutov G. B.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Coordination Chemistry and Functionalization of White Phosphorus via Transition Metal Complexes
Authors: Peruzzini Maurizio , Gonsalvi Luca , Romerosa Antonio
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral and Helical Phase Transitions in Quasi‐1D Molecular Magnets
Authors: Cinti F. , Affronte M. , Lascialfari A. , Barucci M. , Olivieri E. , Pasca E. , Rettori A. , Risegari L. , Ventura G. , Pini M. G. , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design of Crystalline Molecular Networks with Charge‐Assisted Hydrogen Bonds
Authors: Ward Michael D.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Structure—Function Correlations in Oxygen Activating Non‐heme Iron Enzymes
Authors: Neidig Michael L. , Solomon Edward I.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Advances in the Chemistry of Bioactive 3‐Deoxy‐ulosonic Acids
Authors: Banaszek Anna , Mlynarski Jacek
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Automated Assembly of Oligosaccharides: From a Platform Technology to Applications
Authors: Seeberger Peter H.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Binap: An Industrial Approach to Manufacture
Authors: Aspinall Garreth M. , Docherty Gordon F.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Phenyldimethylsilyllithium Reagent
Authors: Fleming Ian
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Reactivity of Difluoromethylene Bridged Diphospha‐Derivatives
Authors: Toetoes R. , Silaghi‐Dumitrescu I.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Solid‐State Photoreactions of 1,3‐Diene Compounds as the Renaissance of Crystal Engineering
Authors: Matsumoto Akikazu
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Computer Modeling of Polysaccharide‐Polysaccharide Interactions
Authors: Taravel Francois R. , Mazeau Karim , Tvaroska Igor
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Advances in Chemistry Applied to Forensic Science
Authors: Rendle David F.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
6‐Hydrazinonicotinamide Derivatives as Bifunctional Coupling Agents for 99mTc‐Labeling of Small Biomolecules
Authors: Liu Shuang
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Oxygen Indicators and Intelligent Inks for Packaging Food
Authors: Mills Andrew
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Process Intensification by Reactive Carriers in Reactive Extraction and Sorption
Authors: Bart Hans‐Joerg
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Derivatization in Mass Spectrometry. Part 5. Specific Derivatization of Monofunctional Compounds
Authors: Halket John M. , Zaikin Vladimir G.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
In vivo cytometry: A spectrum of possibilities
Authors: Chung Alice , Karlan Scott , Lindsley Erik , Wachsmann‐Hogiu Sebastian , Farkas Daniel L.
Published: February 2006

Background

We investigate whether optical imaging can reliably detect abnormalities in tissue, in a range of specimens (live cells in vitro; fixed, fresh ex‐vivo and in vivo tissue), without the use of added contrast agents, and review our promising spectral methods for achieving quantitative, real‐time, high resolution intrasurgical optical diagnostics.

Methods

We use reflectance, fluorescence, two‐photon, and Mie scattering imaging, performed with instrumentation we developed or modified, to detect intrinsic tissue signatures. Emphasis is on spectral/hyperspectral imaging approaches allowing the equivalent of in vivo pathology.

Results

With experimental focus on unstained specimens, we demonstrate the ability to segment tissue images for cancer detection. Spectral reflectance imaging, coupled with advanced analysis, typically yields 90% specificity and sensitivity. Autofluorescence is also shown to be diagnostically useful, with lymph nodes results highlighted here. Elastic scattering hyperspectral imaging endoscopy, using a new instrument we designed and built, shows promise in bronchoscopic detection of dysplasia and early cancer in patients.

Conclusions

The results demonstrate that advanced optical imaging can detect and localize cellular signatures of cancer in real‐time, in vivo, without the use of contrast agents, in animals and humans. This is an important step towards tight spatio‐temporal coupling between such detection and clinical intervention. © 2006 International Society for Analytical Cytology
Immune surveillance of the human central nervous system (CNS): Different migration pathways of immune cells through theblood–brain barrier and blood–cerebrospinal fluid barrier in healthy persons
Authors: Kleine Tilmann O. , Benes Ludwig
Published: February 2006

Background:

Since for immune surveillance, only lymphocytes in the activated state are able to enter normal human central nervous system (CNS), available data are briefly reviewed to reveal lymphocyte transfer through blood‐brain barrier (bbb) and blood‐cerebrospinal fluid barrier (bCSFb).

Methods:

With immuno‐histochemical and ‐cytochemical methods, bbb was studied on brain microvessels and bCSFb on choroid plexus epithelium and microvessels. Lymphocyte transfer capacity on the barriers was determined with blood/CSF cell ratios revealed by quantified multicolour flow‐cytometry of CSF and blood sample pairs.

Results:

Four paths attenuated the restricted transfer of lymphocyte and NK cell subsets (none for B cells) through bbb and bCSFb, preferring memory cells in normal human brain, using different cell adhesion molecules (CAM). CAM pattern changed in choroid plexus where indication of lymphocyte recirculating from CSF into blood may exist in animal brains.

Conclusions:

Since efficiency of migration of blood‐borne lymphocytes into CSF across bbb or bCSFb of normal human brain is not fully revealed, further data are needed to understand the transfer of immune cells across the barriers in health and disease. © 2006 International Society for Analytical Cytology
Laser scanning cytometry in human brain slices
Authors: Mosch Birgit , Mittag Anja , Lenz Dominik , Arendt Thomas , Tárnok Attila
Published: February 2006

Background

The Laser Scanning Cytometry (LSC) offers quantitative fluorescence analysis of cell suspensions and tissue sections.

Methods

We adapted this technique to immunohistochemical labelled human brain slices.

Results

We were able to identify neurons according to their labelling and to display morphological structures such as the lamination of the entorhinal cortex. Further, we were able to distinguish between neurons with and without cyclin B1 expression and we could assign the expression of cyclin B1 to the cell islands of layer II and the pyramidal neurons of layer V of the entorhinal cortex in Alzheimer's disease effected brain. In addition, we developed a method depicting the three‐dimensional distribution of the cells in intact tissue sections.

Conclusions

In this pilot experiments we could demonstrate the power of the LSC for the analysis of human brain sections. © 2006 International Society for Analytical Cytology
Ezetimib influences the expression of raft‐associated antigens in human monocytes
Authors: Orsó Evelyn , Werner Tobias , Wolf Zsuzsanna , Bandulik Sascha , Kramer Werner , Schmitz Gerd
Published: February 2006

Aminopeptidase N (CD13) was recently identified as a molecular target of the cholesterol absorption inhibitor Ezetimib. Regarding that CD13 is expressed in lipid rafts of monocytic cells, we have investigated whether Ezetimib influences raft function in these cells. Expression of raft‐associated antigens (CD11b, CD13, CD14, CD16, CD36, and CD64) was followed by flow cytometry and/or immunoblot in human monocyte‐derived macrophages in response to in vitro administration of Ezetimib. Cellular redistribution of CD13 was assessed by confocal imaging. Ezetimib significantly decreased the surface expression of CD13, CD16, CD64, and CD36; furthermore, it induced a shift of CD13 from plasma membrane to intracellular vesicles, and thus it quite likely modulated monocytic raft‐assembly. © 2006 International Society for Analytical Cytology
Regulation of surface CD163 expression and cellular effects of receptor mediated hemoglobin‐haptoglobin uptake on human monocytes and macrophages
Authors: Ugocsai Peter , Barlage Stefan , Dada Ashraf , Schmitz Gerd
Published: February 2006

Local dysregulation of iron metabolism is suggested to contribute to atherosclerotic lesion development through hemoglobin scavenging pathways. We evaluated the effects of CD163‐mediated uptake of hemoglobin‐haptoglobin (HbHp) complexes on surface CD163 and intracellular heme oxygenase‐1 expression and the secretion of pro‐ and antiinflammatory cytokines by macrophages. We found that increased availability of HbHp complexes triggers the upregulation of surface CD163, and also results in a dose‐dependent secretion of IL‐6 and IL‐10. © 2006 International Society for Analytical Cytology
Novel aspects of systems biology and clinical cytomics
Authors: Bocsi József , Mittag Anja , Sack Ulrich , Gerstner Andreas O. H. , Barten Markus J. , Tárnok Attila
Published: February 2006

The area of Cytomics and Systems Biology became of great impact during the last years. In some fields of the leading cytometric techniques it represents the cutting edge today. Many different applications/variations of multicolor staining were developed for flow‐ or slide‐based cytometric analysis of suspensions and sections to whole animal analysis. Multispectral optical imaging can be used for studying immunological and tumorigenic processes. New methods resulted in the establishment of lipidomics as the systemic research of lipids and their behavior. All of these development push the systemic approach of the analysis of biological specimens to enhance the outcome in the clinic and in drug discovery programs. © 2006 International Society for Analytical Cytology
Differential mechanisms of microparticle transfer toB cells and monocytes: anti‐inflammatory propertiesof microparticles
Authors: Köppler Barbara , Cohen Clemens , Schlöndorff Detlef , Mack Matthias
Published: February 2006

Microparticles are small vesicles released from the plasma membrane of various cell types independently of apoptosis or cell death, are transferred between cells, and carry membrane proteins from one cell to another. We have studied the mechanism of uptake of microparticles by monocytes and B cells. The transfer of microparticles to B cells was almost completely dependent on complement. Incubation of microparticles with serum resulted in opsonization of microparticles with the complement cleavage product iC3b. The subsequent transfer to B cells was mediated by the complement receptor CR2. The interaction between iC3b‐opsonized microparticles and B cells reduced the activation of B cells as measured by expression of MHC class II, CD86 and CD25. In contrast, transfer of microparticles to monocytes was only partially complement dependent, but involved calcium and annexin V, and was found to change the cytokine profile of monocytes towards a reduced release of the pro‐inflammatory cytokines GM‐CSF and TNF‐α and an increased release of the anti‐inflammatory cytokine IL‐10. These data show that microparticles are taken up by B cells and monocytes by different mechanisms and modulate the activation of monocytes and B cells towards an anti‐inflammatory phenotype. Microparticles might be involved in counterbalancing pro‐inflammatory signals arising from tissue injury or inflammation.
Differential roles for CXCR3 in CD4+ and CD8+ T cell trafficking following viral infection of the CNS
Authors: Stiles Linda N. , Hosking Martin P. , Edwards Robert A. , Strieter Robert M. , Lane Thomas E.
Published: February 2006

Lymphocyte infiltration into the central nervous system (CNS) following viral infection represents an important component of host defense and is required for control of viral replication. However, the mechanisms governing inflammation in response to viral infection of the CNS are not well understood. Following intracranial (i.c.) infection of susceptible mice with mouse hepatitis virus (MHV), mice develop an acute encephalomyelitis followed by a chronic demyelinating disease. The CXC chemokine ligand 10 (CXCL10) is expressed following MHV infection and signals T cells to migrate into the CNS. The functional contribution of the CXCL10 receptor CXCR3 in host defense and disease in response to MHV infection was evaluated. The majority of CD4+ and CD8+ T cells infiltrating the CNS following MHV infection express CXCR3. Administration of anti‐CXCR3 antibody reduced CD4+ T cell infiltration (p⩽0.05), while CD8+ T cell trafficking was not affected. Anti‐CXCR3 treatment during chronic disease correlated with improved motor skills and reduced demyelination. The selective effect of anti‐CXCR3 treatment on CD4+ T cells was not the result of either reduced proliferation or modulation in chemokine receptor gene expression. Therefore, CXCR3 signaling has a non‐redundant role in T cell subset trafficking in response to viral infection.