bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the therapeutic effect and application of anticoagulant drugs
Authors: Yang Peiwen
Published: December 2023

As the global population ages, the incidence of cardiovascular disease, stroke, and other diseases associated with thrombosis is also increasing, resulting in a great need for effective anticoagulant treatments. The purpose of this research is to summarize the development of anticoagulant drugs to date, including their drug types, version iterations, mechanisms of action, as well as current challenges and future development directions of anticoagulant drugs. The research will first review traditional anticoagulants, such as vitamin K antagonists and heparins, and discuss in detail their effects, advantages, and limitations. Next, it will give a detailed description of new anticoagulants, such as direct acting oral anticoagulants (DOACs), and analyse their advantages over traditional anticoagulants in terms of safety and efficacy. Finally, it will propose the strategy of individualized therapy for specific population and the combination therapy of anticoagulant therapy and other drugs, and look forward to the development of new anticoagulant drugs in the future. The application of anticoagulant drugs in medicine has a wide range of clinical significance. With the continuous deepening of research, new therapeutic strategies and drugs are constantly being developed and improved, aiming at providing more safe and effective anticoagulant therapy.
Analysis of types of common veterinary vaccines and influencing factors of immunogenicity
Authors: Chen Sun
Published: December 2023

This article provides an in-depth analysis of the types and immunogenicity factors affecting common veterinary vaccines. First, we introduced the common types of veterinary vaccines, including nucleic acid vaccine, attenuated vaccine and conjugated vaccine, and described their immunogenicity characteristics. Then, factors affecting the immunogenicity of veterinary vaccines were explored, including vaccine dose, vaccination route, and vaccination time. Finally, the current research progress on the factors affecting the immunogenicity of veterinary vaccines is summarized, and future research directions are discussed. This study provides important reference for further optimizing the design and immune effect of veterinary vaccines.
Analysis of the clinical display effect of imaging techniques on the staging of gliomas
Authors: Wang Ziyan
Published: December 2023

Glioma is a primary intracranial malignant tumor, which is difficult to be cured and has the characteristics of easy recurrence and high mortality rate, therefore, it is of great clinical significance to accurately grade glioma before operation. Since biopsy of gliomas is relatively difficult and its accuracy cannot be guaranteed, imaging examination has become an important means of clinical grading of gliomas. This paper, through the literature analysis method, reviews the previous studies of applying imaging methods to grade gliomas in China and abroad and summarizes the main techniques of MRI and CT and their grading effects. Finally, this paper finds that MRI and CT can be used to grade gliomas alone, but both have limitations, while the combined application of MRI and CT has high sensitivity and specificity for the diagnosis and grading of gliomas, which makes up for their respective shortcomings, and is worthy of wide application.
The mechanism of lapatinib and its application in breast cancer
Authors: Wang Yuru
Published: December 2023

This paper aims to study the synthetic route, mechanism of action and application of lapatinib in breast cancer. As a common malignant tumor, breast cancer poses a serious threat to the life and health of patients. As an effective targeted drug, lapatinib is significant in treating breast cancer. Its pharmacological effects can block the growth and metastasis of tumor cells by inhibiting specific signaling pathways and affect cancer cells metabolism and drug efficacy. Its molecular mechanism is mainly through targeting the epidermal growth factor receptor (EGFR) to inhibit the proliferation and survival of tumor cells. Studies on lapatinibs drug metabolism and pharmacodynamics also described its metabolism and therapeutic effect in vivo. Secondly, the pathophysiology of breast cancer was summarized, including the pathogenesis, clinical manifestations, and molecular biological characteristics of breast cancer. The therapeutic effect, application, efficacy evaluation, and adverse reaction management of lapatinib were analyzed for the application of lapatinib in the treatment of breast cancer. Moreover, the existing lapatinib synthetic routes were described. Lapatinib has a substantial treatment influence and may effectively decrease harmful reactions when used to treat breast cancer. Nevertheless, additional study is required to ascertain its optimal application and possible mechanism of action in breast cancer treatment.
The vaccine of the type one diabetes
Authors: Ge Jiahua
Published: December 2023

At present, the main patients of T1D (type one diabetes) are adolescents and many complications will occur, which is very harmful to the health of adolescents. This article mainly discusses the development and research progress of T1D vaccine. Current potential vaccines include antigen isolation vaccines, APL, monopeptide vaccines and adjuvant vaccines. Among them, autoantigen IA2-based antigen-specific vaccine Hsp65-6IA2P2 protein vaccine and B9-23 APL-based vaccine can effectively minimize the natural diabetes prevalence in NOD mice, DiaPep277 vaccine is based on heat shock protein 60 (Hsp60), which was displayed to maintain C peptide levels in phase I experiments, but phase II trials are not very successful, and are currently entering phase III experiments. The widely used adjuvant alum was combined with the adjuvant vaccine Diamyd by GAD65. Diamyd therapy has been successful in adults and has been carried out in phase II studies on kids and teens, with phase III trials currently underway in Europe and the United States.
Perimenopause and menopause-Symptoms and treatments
Authors: Du YeYao
Published: December 2023

Menopause, which typically begins around 45-50 and lasts 5-10 years, is a physiological phase relevant to every woman and signifies the end of reproductive ability. Extensive research has shown that the occurrence, development, and end of menopause are related to changes in hormone levels in the body. Many women experience a transitional phase called perimenopause before officially entering menopause, in which they mainly experience menstrual irregularity, including disrupted menstrual cycles and changes in menstrual flow. In addition to the emotional and psychological changes similar to those in perimenopause, the main shift in menopause is the cessation of menstruation. Currently, the treatments for menopausal symptoms primarily involve hormone replacement therapy, although long-term use of hormones elevates the chance of getting breast and endometrial cancer. Non-pharmacological approaches such as exercising and maintaining a balanced diet can alleviate mild symptoms. Traditional Chinese medicine, a popular choice for many patients in East Asia, explains all symptoms, such as liver and kidney weakness and Yin-Yang imbalance. Traditional Chinese medicine practitioners customize herbal formulas based on individual symptoms and use acupuncture to alleviate menopausal symptoms. This review summarizes the symptoms and corresponding treatment approaches for perimenopause and menopause, as well as the limitations of current research.
Progress of EGFR targeted therapy for oral cancer
Authors: Zhao Yujie
Published: December 2023

Because of some uncertain factors such as eating habits and smoking, oral cancer has become one of the serious diseases of the oral and maxillofacial region. Especially in some Chinese cities where betel nut chewing is customary, the incidence of oral cancer has been high. Today, the main treatment methods are still traditional surgical excision, radiation and chemotherapy. However, with the development of medical technology, gene-targeted therapy has become the most important research object. Gene targeting technology is mainly targets the treatment of cancer organ cells, reducing the damage of traditional treatment methods on other areas without lesions. At present, the epidermal cytokine EGFR has been the most studied, and some research results have been put into clinical application. However, in terms of targeted therapy, the development of technology is still incomplete and immature. This article mainly discusses the pathogenic mechanism of EGFR in oral cancer, the synergistic effect of EGFR and other factors on the development of oral cancer, and the research results of EGFR-targeted therapy and combination therapy for oral cancer. The significance of this study is that based on these discussions, it provides reference opinions for treatment that can achieve a good prognosis for oral cancer patients and alleviate the pain of oral cancer patients, and evaluate the current development status of clinical application of EGFR targeted therapy for oral cancer. At present, the targeted therapy technology of oral cancer is still immature. In the future, the role of other factors in the development of oral cancer can be studied, and the influence of the combination of targeted therapy and other therapeutic methods on the treatment results of oral cancer can be studied.
Dificuldades para inclusão de crianças autistas na população neuropediatria de Guarapuava e região
Authors: Lima Gabriel Kluppel , Halick Silvia Mara de Souza
Published: December 2023

O transtorno do espectro autista é caracterizado por distúrbios no desenvolvimento das áreas de comunicação, interação social e comportamento. O presente estudo busca avaliar se crianças com autismo estão sendo incluídas no ensino regular com abordagens pedagógicas e adaptações curriculares para otimizar o seu potencial de desenvolvimento. Trata-se de uma pesquisa qualitativa (entrevistas individuais) que buscou identificar se a inclusão das crianças está ocorrendo e quais as dificuldades mencionadas pelos pais ou responsáveis. Ao todo, 41 pais ou responsáveis legais participaram do questionário e colocaram suas avaliações de forma objetiva e discursiva sobre a inclusão de seus filhos. As respostas indicaram que em uma perspectiva geral o ambiente escolar oferece apoio para o desenvolvimento das principais áreas afetadas pelo autismo, porém ainda com muitas carências. A formação de profissionais habilitados para trabalhar as particularidades dos autistas possibilitará a construção de conhecimento para práticas educacionais que propiciem o desenvolvimento sócio cognitivo dos estudantes com transtorno do espectro autista, como presente na nota técnica Nº 24 / 2013 / MEC / SECADI / DPEE. Os resultados sugerem que são inúmeras as dificuldades de inclusão de crianças autistas no ensino regular, entre elas a falta de preparo profissional, escolar e do diagnóstico tardio de algumas crianças.
Efektivitas Model Pembelajaran Example Non Example dan Numbered Head Together Terintegrasi Pembelajaran Berdiferensiasi terhadap Hasil Belajar Matematika Fase A di Gugus Dwija Wiyata Boyolali
Authors: Utami Yulia Sri , Wardani Krisma Widi
Published: December 2023

Tujuan dilakukannya kegiatan penelitian ini yaitu untuk mengetahui perbedaan efektivitas antara model pembelajaran Example Non Example terintegrasi pembelajaran berdiferensiasi dan model pembelajaran Numbered Head Togther terintegrasi pembelajaran berdiferensiasi ditinjau dari hasil belajar pada mata pelajaran Matematika siswa fase A di Gugus Dwija Wiyata Boyolali. Jenis penelitian yang dijadikan sebagai acuan dalam penelitian ini yaitu penelitian eksperimen semu (Quasi Eksperimental) dengan desain Nonequivalent Control Group. Populasi yang digunakan dalam penelitian ini ialah siswa kelas I di gugus Dwija Wiyata yang terletak di wilayah Kabupaten Boyolali. Sampel dalam penelitian ini diambil berdasarkan teknik Cluster Sampling, dimana total sampel yang digunakan sebanyak 2 sekolah dasar yaitu SD Negeri 2 Ngadirojo dan SD Negeri Sampetan. Hasil pengolahan data menggunakan uji T-test menunjukkan nilai signifikansi pada tabel Sig. (2-tailed) sebesar 0,001 < 0,05 artinya Ho ditolak dan Ha  diterima. Berdasarkan hasil pengolahan data tersebut dapat disimpulkan bahwa penerapan model pembelajaran Example Non Example terintegrasi pembelajaran berdiferensiasi lebih efektif dibandingkan model pembelajaran Numbered Head Together terintegrasi pembelajaran berdiferensiasi ditinjau dari hasil belajar mata pelaajaran matematika kelas 1 gugus Dwija Wiyata.
Quality of Life and Association with Running Habits in Middle-Aged Street Runners: A Cross-Sectional Study
Authors: Pedroso Moreira Daiane , Schneider Vinícius , Ferrari Rodrigo
Published: December 2023

The study aimed to assess quality of life (QOL) and its association with running habits in middle-aged street runners. This is a cross-sectional study, with a sample of 33 amateur street racers (20 men and 13 women), selected for convenience in a running group in Porto Alegre-RS. Due to the COVID-19 pandemic, all data collection was performed online. Two questionnaires, one to assess running habits, with objective questions about the time, weekly hours of practice, and weekly training frequency, and the other to assess QoL (WHOQOL-bref) were won. As a result, street runners’ pair good levels of overall QoL (average: 77 points), as well as in the different domains of QoL (physical domain: 80 points, psychological: 78 points, social: 76 points, and environmental: 75 points, in media). The time of practice was directly associated with higher scores in the overall QoL and physical domain (P <0.01) regardless of age, weekly hours, and weekly frequency. No associations existed between age and running habits in the psychological, social, and environmental domains. The street runners in the running group evaluated showed good QoL, especially in the physical, psychological and overall QoL domains, which was directly and positively associated with the time of practice in the modality.
PENERAPAN MODEL AISAS PADA IKLAN FOCUS NUSANTARA DI MEDIA INSTAGRAM
Authors: Haniifah Raden Ajeng Aszhaafira Farrassayu , Wirasari Ira
Published: December 2023

Iklan digital adalah salah satu wadah untuk menyebarluarkan informasi melalui jaringan internet. Pengguna internet di Indonesia terus mengalami peningkatan, pembuatan iklan digital berpeluang sangat tinggi untuk dilihat oleh audiens dari berbagai wilayah. Tujuan penelitian ini adalah bisa dijadikan sebagai panduan pembuatan iklan digital yang menarik dengan membaca perilaku konsumen dan menggunakan teori AISAS. Metode penelitian menggunakan metode observasi dan studi literatur dengan pendekatan kualitatif deskriptif. Iklan digital dengan memanfaatkan internet untuk menggunakan sosial media sangat menguntungkan dikarenakan sosial media dapat menyebarluaskan informasi secara menyeluruh. Hasil analisis adalah pembuatan iklan digital membutuhkan kreativitas dan pelaku usaha harus mengetahui dan selalu ingin belajar mengenai pola perilaku konsumen serta mengetahui platform yang cocok sesuai target market.
Understanding the STEM student: Holistic strategies from social cognitive theory and the KAPA model of personality architecture
Authors: Iaochite Roberto Tadeu , Cervone Daniel , Azzi Roberta Gurgel
Published: December 2023

This paper identifies and addresses two gaps that typically have separated practical needs in science, technology, engineering, and mathematics (STEM) education from basic psychological science research on non-cognitive factors in educational success. The gaps are: (1) educators want a holistic understanding of students whereas researchers commonly have explored isolated individual-difference variables; (2) educators need assessment procedures that are efficient whereas the most common holistic assessment technique, interviews, is time-consuming and thus inefficient. STEM educators can bridge both gaps by capitalizing on person-centered, idiographic assessment methods in personality science. Specifically, we explain how advances in social cognitive theory, its study of self-efficacy processes, and the person-centered social-cognitive approach known as the Knowledge-and-Appraisal Personality Architecture (KAPA) yield an efficient, holistic method of understanding individual students, their distinctive strengths and weaknesses, and their beliefs about STEM education challenges. We illustrate the theoretical principles through illustrations from ongoing STEM education research.
A COMPREHENSIVE STUDY FOR DEVELOPING A FRAMEWORK FOR MICROSERVICES ARCHITECTURE MIGRATION
Authors:   Amity School of Engineering and Technology , Amity University Chhattisgarh , Raipur, Dhomne Sonal , Upendar Tellaboina ,   Amity School of Engineering and Technology , Amity University Chhattisgarh , Raipur, Soni Dr. Goldi ,   Amity School of Engineering and Technology , Amity University Chhattisgarh , Raipur
Published: December 2023

Building scalable and resilient systems has become a common practice using microservices architecture. Large and complex programs may be split up into manageable components that can be created and deployed separately. Migrating from a monolithic to a microservices architecture is a challenging process that needs careful planning and execution. In this article, we provide a method for migration to a microservices architecture that is based on accepted best practices and industry standards. Three essential phases make up our framework: assessment, design, and execution or Implementation. The assessment stage involves analyzing the existing monolithic application to identify potential microservices candidates. In the design stage, we create a high-level architecture and define microservices boundaries. The implementation stage focuses on building and deploying microservices, along with the necessary infrastructure and tooling. Additionally, we discuss best practices and lessons learned from practical microservices migration projects. Our framework offers a structured approach to organizations seeking to migrate to microservices architecture. Key Words: Monolithic Architecture, Microservices Architecture, Migration Framework
Changes in Lower Extremity Muscle Quantity and Quality in Patients with Subacute Stroke
Authors: Kim Da Hye , Cho Eun Sol , Park Young Sook , Chang Hyun Jung , Park Jin Gee , Kim Jae Yeon , Lee Jeong Hwan
Published: December 2023

Objective: To analyze the changes in muscle mass and quality with time on the paretic and non-paretic sides in subacute stroke patients and identify correlations between the variation of muscle mass and quality and lower limb functions.Methods: Thirty hemiplegia patients diagnosed with stroke participated in this study. To evaluate poststroke muscle changes, longitudinal measurement of muscle mass and quality was conducted with bilateral lower limbs. The elastic shear modulus was measured using shear wave elastography and muscle thickness (MT) of rectus femoris, vastus intermedius, vastus lateralis (VL), vastus medialis, tibialis anterior, and gastrocnemius (GCM) muscles. Functional evaluation was performed using Berg Balance Scale (BBS), Five Times Sit to Stand Test (FTSST). Follow-up was performed at discharge. The muscle mass and quality were compared according to time. We analyzed whether muscle quantity and quality were related to function.Results: MT demonstrated no significant change with time. The elastic shear modulus increased significantly in the paretic VL and GCM muscles and did not change significantly in the muscles on the non-paretic side. Correlation analysis detected that elastic shear modulus in the VL has a cross-sectional negative relationship between BBS and positive relationship between FTSST. There were significant correlation between variation of FTSST and the variation of the elastic shear modulus in VL.Conclusion: Only paretic VL and GCM muscle quality changed in subacute stroke patients and muscle’s property related to lower limb functions. Therefore, the lower extremity requires an approach to muscle quality rather than quantity for subacute stroke patients.
Next-Generation Railway Safety: Designing an Automatic Gate System with Voice-Activated Alarms
Authors: Arafat Md. Yasir , Roy Sonot , Alam Ariful
Published: December 2023

Railway crossings are high-risk areas that demand constant vigilance and attention to ensure the safety of passengers and other road users. Automatic gate systems have been widely used to mitigate these risks, but their effectiveness is limited by the reliance on visual cues and their inability to alert drivers or pedestrians who are deaf or hard of hearing. To address this limitation, we propose a voice-activated automatic gate railway system that uses voice commands to control the gates and employs an audio alarm to alert road users of the approaching train and will give also alarm who walk on the railway. Our system consists of a voice recognition module, a control unit, and a network of sensors that detect the presence of trains and road users. When a train is detected, the gate closes automatically, and the system generates a voice alarm to alert nearby road users. The voice recognition module ensures that the system can be operated hands-free, making it convenient for drivers and pedestrians. Moreover, the audio alarm feature ensures that people with hearing impairments are alerted to the approaching train. We evaluated the performance of the proposed system using a prototype installed at a railway crossing in a high-traffic area. Our results demonstrate that the system is reliable and effective, with a high degree of accuracy in voice recognition and a low false positive rate. Our findings suggest that the voice-activated automatic gate railway system with an audio alarm is a promising solution to enhance the safety and security of railway crossings.
Exploring the Psychological Advantages of Early Computer Education in Early phases of Development
Authors: Kharb Latika , Chahal Deepak
Published: December 2023

The present work aims to explore the significance that teachers attribute to psychological approaches in the process of teaching and learning computer science in early formative years in a Public Educational Institution located in Bawana, Delhi. The research methodology employed is descriptive, using a field design. The study sample consisted of fifteen early formative years teachers. Data collection was conducted through interviews and a Likert scale questionnaire. Quantitative analysis of the data was performed using descriptive statistics. Results reveal that 40% of teachers always consider the basics of computers, while 60% consistently base their planning on the programming relevance in the teaching-learning process. Furthermore, 80% of teachers always prioritize lab activities to promote logical or operational thinking in students, while 20% always utilize recreational activities as a strategy for teaching and learning computer science in their classrooms. However, no respondents indicated consistent use of psychological approaches to enhance the teaching and learning of computer science in a world marked by constant transformation. To summarize, this study highlights the importance of shaping a positive outlook on computer science from an early age to develop students' abstract thinking, logic, and critical reasoning abilities. It emphasizes the need for incorporating psychological approaches to effectively teach and learn computer science among early formative years. By fostering a supportive environment, students can better navigate the challenges of Computer science and embrace its potential as they progress through their educational journey.
Exploring the Scope of Artificial Intelligence (AI) for Lifelong Education through Personalised & Adaptive Learning
Authors: Aggarwal Deepshikha
Published: December 2023

Artificial Intelligence (AI) has the potential to revolutionize lifelong education by enabling personalized and adaptive learning experiences. With AI, educational systems can better understand each individual learner's needs and preferences, tailoring the content and delivery to optimize learning outcomes. This exploration aims to uncover the full scope of AI's impact on lifelong education and discover innovative ways to leverage its power. The objectives of this research include defining the current state of AI applications in lifelong education. We are identifying the challenges and opportunities associated with AI implementation and investigating the ethical implications of AI in education. Through this paper we are designing strategies to integrate AI seamlessly into lifelong learning environments and evaluating the effectiveness of AI-enabled personalized and adaptive learning approaches. We are preparing suggesting the guidelines and best practices for AI implementation in education. These include collaborating with educators, researchers, and policymakers to ensure the responsible and equitable use of AI in lifelong education. We are exploring the potential of AI to enhance teaching and assessment methods and examining the role of AI in supporting continuous skill development and professional growth. This research is also investigating the impact of AI on educational equity and accessibility and identifying areas where AI can augment human expertise and support collaborative learning experiences. The purpose here is to understand the implications of AI on the future of learning and the skills needed for lifelong education in an AI-driven society.
Fault Identification and Protection of Induction Motor Using PLC and SCADA
Authors: Malla Nigam Bam , KC Ajay
Published: December 2023

If not properly maintained, AC induction motors are prone to malfunction. A protective system is put in place to keep an eye on the motor's performance under both normal and trip conditions to remedy this. The system may either modify the input voltage and current to restore normal performance in the event of faults like stator, rotor, bearing, or eccentricity issues or shut down the motor before irreparable harm is done. This guards against sudden shutdowns that could endanger employees, prevents unexpected motor failure, and reduces unforeseen costs. Due to their extensive industrial use, protecting induction motors from overvoltage, overcurrent, under-speed, and overheating is essential. Voltage and current relays, timers, contractors, and other traditional protection techniques are mechanical devices. Both computer-based and PIC-based techniques have fewer mechanical components, although the former needs analog-to-digital conversion cards while the latter does not display the observed electrical parameters. In this work, a PLC based protection technique that does away with contractors, relays, and conversion cards is presented. It keeps an eye on system errors, motor voltages, currents, speed, and temperature while showing alerts on a computer screen. In comparison to conventional, computer, and PIC-based systems, experimental findings show that this PLC-based approach is more precise, efficient, and offers a safer and more visible environment.
Banking on Satisfaction: A Study of Job Satisfaction among Employees in Malaysian Banks
Authors: Daniel Wong Loke Suan Chris , Dass Assoc. Prof. Dr. Mahaganapathy , Nazera Dr. Farzana , Tanvir Kazi
Published: December 2023

The present study aims to examine the many elements that exert an influence on job satisfaction among employees within the banking sector in Malaysia. This study investigates three hypotheses: (1) There exists a negative correlation between work-life balance and job satisfaction; (2) Effective leadership and management have a positive influence on job satisfaction; and (3) Competitive compensation and benefits have a beneficial effect on job satisfaction. The results of the study provide empirical evidence for each of the three hypotheses. The findings indicate that Malaysian banks have the potential to improve employee job satisfaction through the implementation of strategies that prioritize work-life balance, effective leadership and management, and competitive remuneration and benefits packages. These initiatives are expected to enhance personnel engagement and productivity, hence fostering organizational success within the highly competitive Malaysian banking sector.
On Supra iR-Open Set in Topological Spaces and Some Applications
Authors: Abed Sumaya A.
Published: December 2023

In this work we introduce the supra iR-open set in supra topological spaces. , a novel class of supra i-open sets. This class of sets exactly lies between supra regular open and supra i- open sets. We also look at its basic characteristics and compare it to other sorts of data supra semi open sets types as supra i- open set, supra regular open, regular open, regular closed, clopen, supra semi regular open set and supra clopen . By using this set , We introduce and define the notion of supra totally iR-continuous , supra iR-irresolute map and investigate some of its properties. We prove that every supra totally iR- continuous function is supra iR-irresolute, every totally i????-continuous function is supra totally iR continuous and any strongly continuous function is supra totally iR-continuous, on the other hand, we give examples to show that the convers may not be true. At last , We have proved some theorem to discuss the properties of supra iR-normal space and supra iR-regular space.
Enhancement of Power Transfer Capability of Transmission Line Using Thyristor Controlled Series Capacitor (TCSC)
Authors: Malla Nigam Bam , Parajuli Vision , Kalwar Dev Kumar , Karn Prabhat Lal , Aryal Shishir
Published: December 2023

Electricity demand is increasing with the increase in urbanization and industrialization. And to meet this increasing demand, the power generation system has been rapidly increased. But along with increase in generation capacity, transmission capacity also needs to be increased simultaneously. For this, either new transmission line needs to be added in the network or power transfer capability of the existing transmission line needs to be enlarged. Latter is the more preferred choice as it involves less cost and time than to erect the new transmission lines. Power transfer capability of a transmission line can be improved by the adjustment of various parameters of a power system network such as voltage phase angles of the buses connected by the lines, impedance of the lines, etc. For this several power electronics-based FACTS devices have been developed, which are most effective in manipulating these parameters to control the power flow through the lines. In this paper, the use of thyristor-controlled series capacitor (TCSC) is highlighted. In this paper, TCSC is implemented in series with line, connecting two buses, to reduce line series impedance. From the results, it is seen that TCSC implementation increases power transfer capability and stability limit, while improving voltage regulation.
Formal, Informal and Non Formal Education Systems
Authors: Elice Deti , Maseleno Andino , Pahrudin Agus
Published: December 2023

This paper presents formal, informal, and non formal education systems. Education is likened to a ship and students are the captain, then we do not know where the ship will sail. Similarly, education is steered by students who do not know anything, so it will be difficult for us to know where the process of thinking about educational goals without taking into account the social context. Therefore, formal, informal, and nonformal education is expected to shape students to be better. These three types of education are expected to be able to be a breakthrough in programming the behavior of educated people to become more developed in accordance with the times.
Blending Boundaries in the New Normal: Leveraging Technology, AI and Global Perspectives in Modern Education
Authors: Eslit Edgar R.
Published: December 2023

In the dynamic landscape of modern education, the "New Normal" demands innovative approaches to adapt and thrive. This qualitative study explores the integration of technology, artificial intelligence (AI), and global perspectives in blended learning within the context of the "New Normal" in higher education. Through an in-depth literature review and a robust theoretical framework, the research delves into the potentials and challenges of blended learning, AI in education, and international perspectives on teaching and learning. The researcher employed a phenomenological research design and conducted document analysis of scientific books, journals, magazines, research, and online sources, considering the constraints of the "New Normal." Findings revealed five significant themes: (1) Pedagogical Shifts in the "New Normal", (2) Technological Adaptability and Digital Literacy, (3) Digital Equity and Inclusivity, (4) AI in Personalized Learning, and (5) Fostering Global Perspectives and Collaborative Learning. The study contributes to the field by offering valuable insights into enhancing blended learning, embracing AI, and fostering global perspectives in the rapidly evolving educational landscape. By addressing the limitations of the research, this study invites further exploration to revolutionize modern education and embrace the transformative potentials of technology, AI, and global perspectives in the "New Normal."
Kritische criminologie en politiek engagement
Authors: van Swaaningen René , Althoff Martina , Petintseva Olga
Published: December 2023

Critical criminology and political engagement

What role do political commitment and activism play in today’s academic thinking and praxis? After a period in which academics tended to prefer an allegedly ‘apolitical’ position, this changes around 2020, when new social movements against mainly environmental destruction and institutional racism and sexism gain broad support in society. In this context, also academics increasingly demonstrate ‘whose side they are on’. In this article we first examine the current role of critical criminology, and which are the key-developments in the political arena, and then we analyse what this means for the political engagement of academics, and indeed for the way we do research. In this context, we also point at some epistemological, methodological, and societal implications.
When life gives you lemons
Authors: Marzouk Amr
Published: December 2023

When life gives you lemons: Conducting criminological research in authoritarian contexts

This article aims to contribute the discussion on the preferred criminological approach to conducting research under authoritarian conditions. It starts with the review of controversial issues emerging from the literature. Author’s personal research experience is subsequently fused with thus identified conclusions. The two form the basis for a set of critical (both in terms of importance and relativity) guidelines: researchers need to be reflexive regarding their positionality in the field, which, in turn, allows for a better assessment of the risks. Secondly, they need to approach the issue of imperfect data in a critical manner.
Vergroening van de kerk tussen beleid en activiteit
Authors: van der Ziel Tjirk
Published: December 2023

Greening the church between policy and activity – Seeking to do justice to all creation

Churches in the Netherlands are gaining more and more attention to sustainability. The impact seems greater than initiatives in the second half of the last century, when environmental problems in society emerged. Measures are now being taken to save energy or to strengthen biodiversity. But greening is about all of creation, or social and ecological justice; both are closely intertwined. Those who as a church make policy on this can count on more support and activities in the faith community than churches that do not. It should be noted however that Catholic parishes and Protestant congregations differ greatly in this regard.
De Wet verduidelijking burgerschapsopdracht maakt niet veel duidelijker
Authors: Beemsterboer Marietje , Berger Maurits
Published: December 2023

The Act on Clarification of Citizenshop Education is not very clear

With the 2021 Act on Clarification of Citizenship Education, the Dutch legislator wanted to regain control over citizenship education, which was first introduced in 2005. However, the application of the now mandatory citizenship education has not become any clearer: the regulations are extensive but above all complex, and the schools are charged with developing and teaching a multi-dimensional and hyper-sensitive subject
Discriminatie, indirecte discriminatie of geen discriminatie?
Authors: van Bijsterveld Sophie
Published: December 2023

Discrimination, indirect discrimination of no discrimination? The strained discrimination case law of the Court of Justice of the EU in religious matters

This contribution analyses the case law of the Court of Justice of the EU on equal treatment based on religion in the private workplace. The Court’s case law in this area demonstrates a meta-management of the place of religion in the national public domain of the Member States. This case law is [in essence not compatible with] is not in accordance with the spirit of [the space that Member States are entitled to on the basis of] Article 17 of the TFEU that respects the Member States’ church and state relationships. It asserts that dealing with religious pluralism in society is primarily a matter for the Member States. The contribution advocates a thorough revision of the case law discussed.
Kants universele religie van de rede en het jodendom
Authors: Blijdenstein Anna
Published: December 2023

Kant’s universal religion of reason and Judaism

This article examines how Immanuel Kant developed his ideas about a pure and moral religion of reason in direct opposition to Judaism. His writings on Judaism showcase Kant’s ideas about the problematic or dangerous properties of religion and how religious difference was used to delineate a European civilizational identity. An understanding of these aspects of Kant’s work on religion can provide a critical lens to examine contemporary discourses and policies on religious difference.
Het potentieel van narratieve verantwoording
Authors: van de Bovenkamp Hester , Kok Josje , Stoopendaal Annemiek , Pot Anne Margriet
Published: December 2023

Het potentieel van narratieve verantwoording

Verantwoording afleggen over de kwaliteit van publieke dienstverlening is een belangrijke publieke waarde. Verantwoording gebeurt in verschillende verantwoordingsrelaties en op verschillende manieren. Verantwoordingsinformatie komt vaak in de vorm van cijfers, maar steeds meer publieke organisaties experimenteren met andere vormen van verantwoorden. Narratief verantwoorden, via verhalen of verhalende praktijken, is een belangrijke vorm van anders verantwoorden. In dit essay verkennen we, op basis van literatuur, wat narratief verantwoorden is, hoe het werkt en plaats kan vinden op verschillende niveaus, en wat het betekent voor toezicht.
Waarom reputatie meer is dan beeldvorming
Authors: Stegeman Rick , Wesdorp Julia , Ropes Emma
Published: December 2023

Waarom reputatie meer is dan beeldvorming

In dit essay bespreken wij het belang van reputatie in het toezicht. Wij stellen dat reputatiemanagement niet slechts gaat om het beïnvloeden van de beeldvorming over de eigen organisatie, maar essentieel is voor de effectiviteit en legitimiteit van toezichthouders. Allereerst bespreken we Daniel Carpenter’s (2010) theorie over de rol van reputatie in het toezicht. Daarna laten we zien dat deze theorie bij uitstek geschikt is om het toezicht van nu te begrijpen. Ten slotte richten we ons op het wetenschappelijk onderzoek naar de rol van reputatie in de toezichtpraktijk, dat laat zien wat een goede reputatie oplevert voor toezichthouders en hoe toezichthouders trachten een goede reputatie te cultiveren.
IMPLEMENTASI PEMBELAJARAN BERBASIS PORTOFOLIO PADA PEMBELAJARAN IPS DI KELAS V SDI WOOWONA 2
Authors: Ma Anselmus Me , Novianti Chatarina
Published: December 2023

This research aims to find out how portfolio-based learning is implemented in social studies learning in class V of SDI Woowona 2, Rewarangga Village, East Ende District. This research is a qualitative research. Research subjects were class V students and class V teachers at SDI Woowona 2. Data collection techniques used observation, interviews and documentation methods. Data analysis techniques include data reduction, data display (data presentation), and conclusion drawing/verification (drawing conclusions). Meanwhile, checking the validity of the data was carried out using triangulation techniques, namely source triangulation and technical triangulation. The results of the research show that the implementation of portfolio-based learning in social studies learning in class V SDI Woowona 2 uses the method of creating an active student learning atmosphere, participatory learning, cooperative learning groups, reactive learning and fun learning. The obstacles faced in implementing portfolio-based learning in social studies learning in class V SDI Woowona 2 are that the use of time in portfolio-based learning in social studies learning takes a long time, costs money to create work, teachers are not diligent and patient in assessing students' work, teachers have not able to provide students with an understanding of the importance of responsibility.
PENINGKATAN HASIL BELAJAR MELALUI PEMBELAJARAN KOOPERATIF TIPE NUMBER HEAD TOGETHER (NHT) PADA MUATAN IPS DI SDI OTOMBAMBA
Authors: Welu Felix
Published: December 2023

This research is class action research (Class Action Research) which aims to improve social studies learning outcomes in class IV SDI Otombamba. The implementation of this research consisted of four stages, namely planning, implementation, observation and evaluation and reflection. The subjects in this research were 27 class IV students at SDI Otombamba, 14 male students and 13 female students. Data on the level of students' understanding of social studies subjects, material on natural appearance and socio-cultural diversity through giving tests at the end of the cycle. Data on student activity during the learning process is obtained from the results of observations filled in on the observation sheet. Data obtained from observations were analyzed qualitatively while data from sociology learning results were analyzed quantitatively. The research results showed that in the first cycle which was completed individually, only 11 students or 40.7% of the 27 students met the minimum completion criteria (KKM). Classically it has not been fulfilled because the average value obtained was 58.7. Meanwhile, in cycle II, 26 students or 96.7% had fulfilled the KKM and classically had been fulfilled, namely the average score obtained was 75.9. In cycle I, student learning outcomes were in the medium category. This means that student learning outcomes regarding subject matter have increased from the medium to high category. Based on the results of the research above, it can be concluded that the learning outcomes of SDI Otombamba students through the application of the Numbered Heads Together (NHT) learning model have increased.
STRATEGI MENGATASI KEKERASAN TERHADAP ANAK MELALUI PESANTREN RAMAH ANAK
Authors: Nurlaela Nurlaela , A. Muh. Mujaddidi , Arifin Syamsul
Published: December 2023

This article aims to find out strategies for overcoming violence against children through child-friendly Islamic boarding schools. This study was guided by a problem formulation, namely how to overcome violence against children through child-friendly Islamic boarding schools. This study is a literature review or often called a literature review. The analysis approach uses a content analysis approach. The author found that the strategy for overcoming violence against children through Child-Friendly Islamic Boarding Schools is: first, training of teaching staff; second, the establishment of a code of ethics and anti-violence policies; third, restorative approach; fourth, education on children's rights; fifth, the role of parents and family; sixth, carry out monitoring and evaluation; seventh, campaign and promotion of Child Friendly Islamic Boarding Schools; and eighth, leadership commitment. The results of this study contribute to strengthening the foundation for developing models and guidelines for Islamic boarding schools to become Child Friendly Islamic Boarding Schools.
PERAN BIPA SEBAGAI MEDIA PROMOSI DAERAH (KEK MANDALIKA)
Authors: Putra Agus Darma , Wahidah Baiq Yulia Kurnia
Published: December 2023

Indonesian for Foreign Speakers (BIPA) plays a very active role as a regional promotional media. In this research, BIPA plays an active role as a regional promotional media, especially in the Mandalika Special Economic Zone (KEK). In this case, Mandalika utilizes natural resources and the cultural diversity of the local community as a tourist attraction that is introduced to foreign speakers. With the active role of BIPA, Mandalika has become a very popular tourist destination both locally, nationally and internationally. The aim of this research is to describe the role of BIPA as a regional promotional media in the Mandalika Special Economic Zone (KEK). Meanwhile, the method used in this research is a descriptive method with a qualitative approach. The results of this research are: (1) BIPA as a tourism promotion media in the Mandalika Special Economic Zone; (2) BIPA as a media for promoting religious culture; (3) BIPA as a media for promoting the art of Gendang Belek; (4) BIPA as a promotional media for the Bau Nyale tradition; and (5) BIPA as a media for promoting regional languages (Bahasa Sasak), and BIPA as a media for diplomacy.
Algoritmos para classificação estrutural de proteínas
Authors: Lima Lucio Paccori , Dos Santos Marcos Augusto
Published: December 2023

Neste trabalho, estruturas de proteínas são mapeadas em um vector space model para sua manipulação em ambientes que remetem às modernas máquinas de busca (Yahoo, Google etc). Instrumentos da álgebra linear junto com a regressão logística com modificações esteiam um novo algoritmo, aqui denominado Adhoc, para a busca de assinaturas de estruturas tridimensionais. Este método transcende a aplicação aqui discutida; pode ser utilizado de forma geral em outros problemas de recuperação de informação. Para a validação, testamos as ideias para classificar proteínas em seus respectivos grupos e famílias, a partir da estrutura já determinada. Os resultados apresentados são animadores e outros experimentos estão sendo providenciados.
Incidences of Aspergillus sp infections in Brazil
Authors: Gomes Felipe José Ferreira , Motta Rondinele Ribeiro
Published: December 2023

The main objective of this research was to analyze the incidence of Aspergillus sp in Brazil, as well as to research the species that cause the most infections and the impacts caused by fungi on Brazilian humanity. This is an exploratory descriptive research from reviews and bibliographic research in scientific articles from the database Scientific Electronic Library Online - Scielo, in the periods 2013 to 2023; Given the above, the need arose to research this subject from the questions: What are the incidences of infections caused by Aspergillus sp in immunosuppressed patients in Brazil? And which fungal species cause more infections? In which Brazilian population? The dissemination of these infections is due to the ingestion of contaminated food, produced without observations as to Good Agricultural Practices (GAP), affecting immunosuppressed patients, senile and hospitalized patients, causing serious neoplasms in humans, by these mycotoxin-emitting fungi, triggering aspergillosis, responsible for major complications in Brazil, and the most affected human organs are the lungs, heart, kidneys, gastrointestinal tract, liver, etc. The A. flavus, A. brasilienses and A. fusarium are the ones that most affect the essential organs and the Brazilian population, especially the lung, which is responsible for serious neoplasms, leading to death in a few days.