bluuebunny/crossref_metadata_2025 huggingface dataset:
Singular Soliton, Shock-wave, Breather-stripe Soliton, Hybrid Solutions and Numerical Simulations for a (2+1)-Dimensional Caudrey-Dodd-Gibbon-Kotera-Sawada System in Fluid Mechanics
Authors: Liu Shaohua , Tian Bo
Published: January 2022

In this paper, a (2+1)-dimensional Caudrey-Dodd-Gibbon-Kotera-Sawada system is investigated in fluid mechanics via the symbolic computation. With the help of the Hirota method, we derive the singular soliton, shock-wave, breather-stripe soliton and hybrid solutions. Based on the finite difference method, we get the numerical one-soliton solutions. We graphically show the singular and shock-wave solutions, and observe that the singular one-soliton solutions are blow-up and unstable, but the shock-wave solutions are nonsingular and stable. We observe that the breather-stripe soliton moves along the negative direction of the y axis, where y is a variable, and the amplitude and shape of the breather-stripe soliton remain invariant during the propagation. We graphically demonstrate the interaction among a rogue wave, a periodic wave and a pair of stripe solitons: a rogue wave arises from one stripe soliton; the rogue wave interacts with the periodic wave, the rogue wave splits into two waves and then the two waves merge into a wave; the rogue wave fuses with the other stripe soliton. We graphically present that the numerical solutions are well approximate to the analytic solutions.
Shoreline Dynamics of Reserved Region of Meghna Estuary and It Impacts on Lulc and Socio-Economic: A Case Study on Nijhum Dwip
Authors: Chowdhury Piash , Sikder Md. Bahuddin
Published: January 2022

The southern side of Bangladesh is more unstable due to carrying massive discharge and transportation of heavy sediment through Meghna estuary. Shoreline representation is extremely important to regulate the dynamic nature of coastal areas. This paper focused on measuring the change of shoreline, evaluating the LULC (land use & land cover) due to the shoreline dynamics by using a multi-date (1978-2018) satellite image and changes of the social-economic condition due to the shoreline dynamics by a direct interview-based questionnaire survey of Nijhum Dwip, Hatiya, Noakhali, Bangladesh. Shoreline changes have been estimated as net shoreline movement (NSM), endpoint rate (EPR), and prediction based on the EPR rate. A total of 104% were increased with the rate of -17 m to 86 m per year shoreline change. Most of the accretion occurred in the Northern and Western sides; erosion only occurred on the Southern side. It can be estimated that the shoreline will increase by 2.2 km, with an area of 644.32 hectares in 2028. LULC mainly changed due to accretion activities in the study area. Barren land, mudflats, homestead vegetation, grassland were increased by 0.63%, 0.65%, 14%, 6% drastically of its total area, respectively. Cropland, green vegetation, and mangrove vegetation were decreased by 12%, 9%, and 0.11%, respectively, drastically of its total area. It can be appraised that the vegetated area will increase 5103.39 hectares in 2028. Thus it was also determined that shoreline change has a positive impact on migration, economic activities, and tourism. As newly accreted land which was cheap or could stay through "Bndobostho" and people were joining various working fields which had been created in new accreted land and farmer were increased. This paper intends to contribute several suggestions to the socio-economic development of native people and future strategic management of the reserved coastal area.
A Systematic Review to Identify Implementation Targets of Mindfulness-Based Interventions for Cardiovascular Risk to Enhance Engagement with Racial/Ethnic Minorities
Authors: Sanchez Tonya Faye , Santamaria E. Karina , Rubenstein Dana , Brewer Judson , Operario Don
Published: January 2022

Cardiovascular disease (CVD) is a persistent public health challenge and racial/ethnic minority populations experience disparities in CVD risk factors. Mindfulness-based Interventions (MBI) have been examined as a strategy to address CVD risk factors, though their potential for implementation with racial and ethnic minorities remains unclear. This review examines primary interventions studies testing the impact of MBI on CVD risk, with a focus on critical appraisal of implementation characteristics (i.e., intervention design, delivery, uptake, and contextual factors) relevant to the engagement of racial/ethnic minority populations. A systematic review identified 30 studies published through January 2022 for inclusion. Included studies were randomized controlled trials testing meditation or mindfulness-based interventions against any control to measure change or improvement in cardiovascular health measures or risk behaviors in adults living in the United States or territories. The Oxford Implementation Index was utilized to identify and extract relevant implementation data, and critical analysis of each study’s implementation process was conducted. All identified studies were published between 2011 and 2021 and represent early or pilot stages of research. As such, limitations and barriers in implementation strategies for racial/ethnic minority populations were identified. This review outlines several potential targets for future research to enhance engagement with racial/ethnic minorities.
­­SARS-CoV-2 membrane protein: from genomic data to structural new insights
Authors: Marques-Pereira Catarina , Pires Manuel , Gouveia Raquel , Pereira Nadia , Caniceiro Ana , Rosário-Ferreira Nicia , Moreira Irina
Published: January 2022

Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) is composed by four structural proteins and several accessory non-structural proteins. SARS-CoV-2's most abundant structural protein, Membrane (M) protein, has a pivotal role both during viral infection cycle and host interferon antagonism. This is a highly conserved viral protein, thus an interesting and suitable target for drug discovery. In this paper, we explain the structural and dynamic nature of M protein homodimer. To do so, we developed and applied a detailed and robust in silico workflow to predict M protein dimeric structure, membrane orientation, and interface characterization. Single Nucleotide Polymorphisms (SNPs) in M protein were retrieved from over 1.2 M SARS-CoV-2 genomes and proteins from the Global Initiative on Sharing All Influenza Data (GISAID) database, 91 of which were located at the predicted dimer interface. Among those, we identified SNPs in Variants of Concern (VOC) and Variants of Interest (VOI). Binding free energy differences were evaluated for dimer interfacial SNPs to infer mutant protein stabilities. A few high-prevalent mutated residues were found to be especially relevant in VOC and VOI. This realization may be a game changer to structure driven formulation of new therapeutics for SARS-CoV-2.
Climate change drives earlier wildfire season onset in California
Authors: Madakumbura Gavin D. , Moritz Max A. , McKinnon Karen , Rahimi Stefan , Norris Jesse , FU RONG , Hall Alex
Published: January 2022

Wildfires in California have become more frequent in recent decades, with increasingly devastating impacts. The fire season is also lengthening, with an earlier onset. This trend has been hypothesized to be driven by climate change, but it has yet to be quantitatively attributed to climate drivers. Using a comprehensive fire occurrence dataset, we analyze fire season onset and climate controls on its variability and change during 1992-2018 in California’s forested ecoregions. Onset shows an advancing trend, by 14 days in Northern California and 17 days in Southern California. In Southern California, this trend is dominated by decreasing winter precipitation, possibly natural in origin. By contrast, in Northern California, the largest contributor to the advancing onset is a springtime temperature increase, driven to a large degree by climate change. No matter what the dominant contributor to the trend is, the influence of climate-change-driven warming on onset has already emerged from the influence of natural temperature variability in both regions. Given inevitable future warming trends, this influence will continue to accelerate fire season onset and exacerbate wildfire risks in California in coming years.
Simple synthesis of novel Lanthanum doped Copper oxide nanoparticles for wastewater treatment: A comparison between Experiment and COMSOL simulation
Authors: Masood Arslan , Iqbal Tahir , Afsheen Sumera , Riaz Khalid , Nabi Ghulam , Khan Muhammad Isa
Published: January 2022

Photocatalysis is a promsing technique for remediation and decontamination of waste water. This research work focuses on the synthesis of pure and lanthanum (La)- (1, 2 and 3 wt%) doped copper oxide nanoparticles (CuO-NPs) via a simple, cost effective and efficient sol-gel process. Differnet characterization techniques such as UV-vis, PL, SEM, XRD, EDS and FTIR are used to investigate optical, compositonal, structural and morphological properties of the synthesized material. Quite interestingly, doping of rare earth element La has reduced the particle size (52.02 ± 0.04 nm to 42.39 ± 0.02 nm) of CuO-NPs. Additionaly, with doping, the band gap and electron hole recombiantion rate is also reduced. Band gap has shifted towards visible region (3.13 ev to 2.85 ev) which makes it an excellent mateiral for photocataysis. Methylene blue (MB) dye is used as model contamination. Photocatalytic degradation efficieny of 79% is obtained in 150 min by La0.02Cu0.98O against MB under natural light irrradiation. Band gap is increased upon futher doping which attributes to the reduced catalytic efficiency to 73% for La0.03Cu0.97O. Theoratical photocatalytic activity of CuO-NPs against MB dye with particle size of 50nm is carried out using COMSOL Multiphysics 5.3a Licenced version in order to corelate the experimental and theoratical results.
Insights into highly effective catalytic persulfate activation on oxygen-functionalized mesoporous carbon for Ciprofloxacin degradation
Authors: xiong ying , Dai Xiaolei , Liu Yuanyuan , Du Chunyan , Yu Guanlong , Xia Yan
Published: January 2022

Nanocarbons have been demonstrated as promising carbon catalysts for substituting metal-based catalysts for the green treatment of wastewater. In this study, oxygen-functionalized mesoporous carbon (OCMK-3) was prepared by wet oxidation and exhibited high catalytic performance against ciprofloxacin (CIP) by activation of persulfate. The effects of environmental parameters (pH, temperature, coexisting ions) and process parameters (temperature, sodium persulfate concentration, catalyst agent dosage, initial concentration) on the removal of CIP were investigated. Compared with the pristine ordered mesoporous carbon (CMK-3), the removal efficiency of CIP by OCMK-3 was increased by 32% under optimal conditions. This rise in activity was attributed to the increase in oxygen-containing functional groups, porosity and specific surface area of OCMK-3 with improved structural defects and electron transfer efficiency. Furthermore, based on active species scavenging experiments, a dual-pathway mechanism of the radical and nonradical pathways was discovered. The rational degradation pathway of CIP was investigated based on liquid chromatography-mass spectrometry (LC-MS). In addition, the OCMK-3/PS system exhibited high decomposition efficiency in pharmaceutical wastewater treatment. This study provides an in-depth mechanism for the degradation of organic pollutants by carbon-based PS-AOPs and provides theoretical support for further studies.
Effects of Exogenous Gibberellic Acid in Huanglongbing-affected Sweet Orange Trees under Florida Conditions—II. Fruit Production and Tree Health
Authors: Singh Sukhdeep , Livingston Taylor , Tang Lisa , Vashisth Tripti
Published: January 2022

Fruit production of sweet orange (Citrus sinensis) in Florida has been declining with the presence of Huanglongbing [HLB; Candidatus Liberibacter asiaticus (CLas)] disease. Through disruption of the balance of endogenous hormone levels, the disease has negative impacts on fruit development, mature fruit retention, and overall tree health. Thus, the goal of this research was to determine whether plant growth regulator gibberellic acid (GA3) can be used to improve the production issues caused by HLB. For ‘Valencia’ sweet orange, although foliar applied GA3 from September to January (33 mg·L−1 for five applications) resulted in 50% decrease in bloom the following spring (results presented in Tang et al., 2021), this treatment did not cause reduction in yield of current and subsequent crops. Moreover, a 30% average increase in yield in GA3-treated trees was observed over a period of 4 years. The size of mature fruit was also increased (by 4% to 5%) with reduced fruit drop rate near harvest in GA3-treated trees compared with nontreated control trees. Furthermore, the canopy density, an indicator of HLB severity, was maintained in trees applied with GA3 (from 90.8% light interception to 90.4%). In contrast, there was a substantial decrease in canopy density for control trees (from 91.6% to 84.0%). Gene expression analysis of abscission zone and leaves indicated that GA3-treated trees had enhanced oxidative stress mitigation mechanism and plant defense response. Given that there is no cure for HLB, these results presented a possible remedy of using GA3 in sustaining tree health for field-grown sweet orange affected by HLB.
EFFICACY OF MONITORING AND EVALUATION SYSTEMS IN THE PERFORMANCE OF GOVERNMENT SPONSORED PROJECTS
Authors:   Post Graduate., Lenna Muriuki Nkatha , Nyonje Raphael ,   Associate Professor., Lilian Omutoko Joyce ,   Senior Lecturer.
Published: January 2022

This paper is based on the efficacy of monitoring and evaluation systems in the performance of government sponsored projects. A project is a temporary endeavor undertaken to create a unique product, service or result. Monitoring and evaluation is a key component in project management. The value for monitoring and evaluation is to promote and enhancing successful performance of government sponsored programs. The basic goal of monitoring and evaluation is to periodically track implementation, efficiency and project effectiveness increasing the value and interest to beneficiaries. Monitoring and evaluation system is designed within the organization, which includes indicators, methods, and procedures that can be used to determine whether a project was carried out according to plan and achieved the desired results. Projects have to be completed as expected and to the stakeholders satisfaction and eventually be sustainable. The importance of monitoring and evaluation is to enhance the successful delivery of the projects. This paper was focused on issues dealing with the role of M&E System in the Performance and Management of government Sponsored Projects Relevance of M&E Systems Performance of Projects and Stakeholder Participation in Projects and barriers to the Implementation of Project Monitoring and Evaluation system. The study recommendations include that governmental or non-governmental organization and institutions need to step in advancing the capacities of monitoring and evaluation to check the direction that projects take. Project managers should therefore work hard for change attitudes and perception on the value of M&E for their personnel and finally organizations should start by improving their capacities (personnel, tools, knowledge and skills).
DEVELOPMENT OF RIDEE LEARNING MODEL (READING, INJECTING, DISCUSSING, EVALUATING, EXPOSURING) TO IMPROVE SELF REGULATED LEARNING (SRL ) AND SCIENCE LEARNING OUTCOMES FOR JUNIOR HIGH SCHOOL STUDENTS
Authors:   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., Fauziana Ardia , Subchan Wachju ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121., a Indrawati ,   Department of Science Education Magister, University of Jember, Jember, Indonesia 68121.
Published: January 2022

The application of learning models that are in accordance with the characteristics of students and the characteristics of subjects that can change or improve students skills in mindsets is very rare or even non- existent. The learning model that will be developed is RIDEE. Where the RIDEE learning model comes from combining the two previous learning models into a learning model that is expected to be applied practically, effectively, and validly. Science is one of the sciences that has the characteristics of events in everyday life. In everyday life, it is necessary to increase students skills where these skills can make it easier for students to achieve learning goals, both in science lessons and in other subjects. The skill or ability is the self-regulation ability for the students themselves (Self Regulated Learning), in science learning the self- regulation ability in students is very necessary, where students will know to what extent the students inability or understanding of their own academic and non-academic abilities students, so that students are expected to have good self-regulation values to be applied in everyday life, both in the learning process and in the process of social communication in students daily lives. Thus the academic ability of the students themselves will also be able to increase, especially in science learning outcomes in junior high school. This study aims to examine the effectiveness of the use of brain-based learning materials on the excretory system on students self-regulated learning skills. The method in this study is 4D, with three meetings in three different classes. The data analyzed was obtained from the value of Self Regulated Learning.
FAILURE MODE AND EFFECT ANALYSIS FOR THREE DIMENSIONAL RADIOTHERAPY AT AIN SHAMS UNIVERSITY HOSPITAL
Authors:   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University., Sobhy Muhammad Gehad , Aly Sharawy Iman ,   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University., Mohamed Abdalla Hatem ,   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University., Hakim Abdel ,   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University., Refaat Meckawy Ghada ,   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University., Nagib Abdel Hakim Khalid ,   Department of Oncology and Nuclear Medicine, Faculty of Medicine, Ain Shams University.
Published: January 2022

Introduction: Three-dimensional radiotherapy (3D) is an important modality in management of cancer. This complex process is liable to many types of errors. Risk management approaches are mandatory to decrease the risk of these errors. Failure mode & effect analysis(FMEA) is a proactive risk assessment strategy used to in identify and anticipate potential errors and to take action before a radiation incident occurs. Aim: The aim of this study is to apply a proactive risk analysis of the 3D radiotherapy process,to quantify the most significant sources of failures using FMEA & to recommend risk reduction measures. Methods: A FMEA was conducted over 12-months period at Clinical Oncology and Nuclear Medicine Department at Ain-Shams University Hospital. A detailed process map for 3-D radiotherapy technique was created starting from the decision taken for radiotherapy till the end of radiotherapy sessions. The Delphi method was used in this study to achieve consensus among participants about the level of risk associated with failure modes.Semi-structured interviews wereconducted with twenty radiation personnel to identify potential failure modes in each step of 3-D radiotherapy process. Scoring of the failure modes was identified in round 1, according to Severity, Occurrence and lack of detectability scores. Round 2 confirmed the results of round 1.In Round 3:Risk mitigation strategies were suggested. Results: The 3-D radiotherapy process map consisted of 69 process steps of the 10stages of the3-D radiotherapy process.One hundred â€“fifty-two failure modes were identified. Thirty-two top ranked failure modes were prioritized according to RPN and severity scoring. An affinity diagram for these preventive measures was constructed. Conclusion: FMEA is an effective proactive risk assessmentapproach in 3-D radiotherapy as elaborated by identification of potential failure modes,focusing on the top ranked ones and also suggesting risk reduction measures.
PELATIHAN PENANGANAN CEDERA OLAHRAGA MELALUI METODE PRICE, SPORT MASSAGE, PEMASANGAN KINESIO TAPINGPADA AT LET DAN PELATIH SEKOLAH SEPAK BOLA (SSB) TUNAS KAILIDI KOTA PALU
Authors:   Pendidikan Jasmani Kesehatandan Rekreasi Universitas Tadulako, Palu., Bulu Baan Addriana , Sri Rejeki Hendriana ,   Pendidikan Jasmani Kesehatandan Rekreasi Universitas Tadulako, Palu., a Marhadi ,   Pendidikan Jasmani Kesehatandan Rekreasi Universitas Tadulako, Palu., Kristanti Liloi Delvi ,   Pendidikan Jasmani Kesehatandan Rekreasi Universitas Tadulako, Palu.
Published: January 2022

HasilpengamatandanwawancarakepadabeberapaTimPelatihdanatletSSBTunasKaili,dari25atletyangpernahmengalamicederasebesar40%(10atlet)dansebesar60%(15atlet)belumpernahmengalamicedera.Bagiancedera atlet SSBTunasKailidi Kota Palu dari25 atletsebagianbesarcederapada pinggangsebesar8%(2 atlet),untukcederaankle(sprain)sebanyak68%(17atlet)sedangkancederayangdisebabkankarenanyeriototsebesar24%(6atlet).sebagianbesarcederapadapinggangsebesar20%(2atlet).FenomenayangterjadidiKotaPaluberdasarkanhasilobservasiyangdilakukandiSSBTunasKailimengenaipengetahuantentangrecoverykhususnyaterkaittindakanP.R.I.C.E,SportMassage dan Pemasangan Kinesio Tape masihsangatrendah, bahkan ada beberapa Pelatihdan AtletyangtidaktahutentangapaituP.R.I.C.E,kalaumassagesudahtahutapisekedarmassagetradisionaldankinesiotapemerekasudahtahudanpernahmelihattapimerekabelumtahucaramemasangnya,aparasanya,manfaatnyauntukapadankapandipakainya.Permasalahanberdasarkanpadasituasidankondisiyangsesungguhnya,yakni:1)Banyaknyacedera olahraga dilapangan yang tidak ditangani dengan benar,2)Kurangnya tenaga masseurdiKota PalukhususnyaSportMassage.3)BanyaknyakejadiancederapadasaatpertandingannamunAtlet,PelatihatauOfficialbelumtahucarapenangananyangbenardenganpendekatanP.R.I.C.E,4)KurangnyapengetahuanPelatihdanAtlettentangpenggunaan kinesiotape. Kegiatan PPM yang dilaksanakan dengan acara tatap muka dan praktek tindakan P.R.I.C.E, sport massage danpemasangan kinesio taping berjalan dengan baik dan lancar. Hal tersebut ditandai dengan adanya kesungguhan daripeserta untuk mengikuti secara aktif pelaksanaan kegiatan pelatihan dari awal sampai akhir. Peserta kegiatan berjumlah25 orang peserta dengan latar belakang pelatih dan atlet SSB Tunas Kaili Kota Palu dan lokasi penyelenggaraanpelatihan di Lapangan Sepak Bola NunuKota Palupada tanggal 15 Agustus 2021. Setelah kegiatan pendampingandapat disimpulkan 16% (4 orang) dari jumlah peserta yang ikut pelatihan bisa atau mampu menjadi masseur (pemijat)yang handal, sebanyak 72% (18 orang) mampu melakukan tindakan pertama dan lanjutan pada cedera baik secaramandiri ataupun berkelompok serta mampu memasang kinesio taping dnegan benar, Sedangkan sisanya sebesar 12% (3orang) masih banyak melakukan kesalahan dan kurang telitinya dalam tindakan. Manfaat yang diperoleh peserta adalahdapat memahami, mempraktekan dan menerapkan keterampilannya dengan kualitas yang lebih baik dan diharapkankebugaran atletsepakbola kotapalusemakin meningkatdan mendapatkan prestasiyang maksimal.
Outpatient diagnosis of endogenous intoxication in surgery
Authors: Solomakha A. A. , Vlasov A. P. , Gorbachenko V. I.
Published: January 2022

Introduction. In recent years, there has been an increase in the number of patients with purulent surgical diseases with severe endogenous intoxication and renal dysfunction. The problem of early diagnosis of purulent diseases is still not completely solved. The health systems of developed industrial Western countries do not always manage to provide all citizens with adequate high-quality medical care. This is due to the current health crisis. The problems of diagnosis, treatment, prevention and prediction of purulent diseases in surgery can be solved thanks to advanced digital technologies.

Aim of the study. To develop a diagnostic method for early detection of endogenous intoxication in outpatient surgery.

Materials and methods. We created three groups of observations for the design of a neural network system for the diagnosis of endogenous intoxication syndrome and chronic kidney disease. In the first group, the hematological parameters of 150 healthy people were studied. In the second group, the hematological parameters of 40 patients with chronic kidney disease without chronic kidney failure were studied. The third group included 84 patients with chronic kidney disease and end-stage chronic kidney failure. The following 25 laboratory parameters were studied: hemoglobin, red blood cells, color index, white blood cells, rod-shaped neutrophil white blood cells, segmental neutrophil white blood cells, eosinophils, basophils, lymphocytes, monocytes, ESR, total protein, albumins, urea, creatinine, bilirubin, beta-lipoproteins, cholesterol, glucose, seromucoid, sialic acid, potassium, sodium, chlorine, calcium. Statistical, neural network and algorithms with elements of fuzzy neural networks were used on a sample consisting of hematological parameters of 274 patients with chronic kidney disease and healthy ones based on 25 laboratory parameters. Mathematical modeling was carried out at the Department of “Computer Technologies” of the Penza State University.

Results. The effectiveness of neural network diagnostics of endogenous intoxication syndrome in patients with chronic kidney disease without chronic kidney failure reached 88.2%, and in patients with chronic kidney disease and chronic kidney failure – 97.6%.

Conclusion. The neural network method of diagnosis can help improve the early diagnosis of endogenous intoxication syndrome in outpatient surgery.
The impact of regional and catchment characteristics on long-term runoff in small agricultural catchments in Latvia
Authors: Veinbergs A. , Lagzdins A.
Published: January 2022

The explanation of runoff behavior is challenging due to variable weather conditions, and catchment characteristics. The parameter equifinality in catchment-scale models turns into the uncertain distribution of water balance components even though models tend to represent total runoff well. This study aims to discuss long-term runoff and evapotranspiration (ET) variations affected by regional allocation and catchment characteristics in Latvia. The study applies the observational runoff data from drainage fields and small catchment scales. The sites represent the spatially different regions in Latvia with relatively variable yearly precipitation amounts. The robust data of surface slope gradients, the share of subsurface drainage systems, arable and grasslands, and ditch networks describes the differences in the catchment characteristics. The results reveal that higher long-term yearly average runoff and ET rates are experienced by the regions with higher yearly precipitation amounts. Simultaneously, the higher the long-term yearly average precipitation and steeper the surface slope gradient, the proportionally (%) higher is the runoff contribution into the water balance. When compared with the small catchments, the soil profiles at drainage fields might store more water after the subsurface drainage runoff is running short. Consequently, the small catchments might experience the later response of subsurface drainage runoff after the dry seasons.
E-module design of sport modification and cybergogy-based small games
Authors: Rosmawati Rosmawati , Zarwan Zarwan , Astuti Yuni , Sari Dessi Novita , Zulbahri Zulbahri , Erianti Erianti
Published: January 2022

The low learning outcomes of students in the subject of modification of sports and small games are considered as the problem in this research that is mostly caused by the lack of learning media facilities for students in the online classes that leads them to difficulty in understanding the provided learning materials. This study aims to develop an e-module on the subject of modification of sports and small games. The ADDIE development model is being used in this Research and Development (R&D). There are several activities needed as the research method, such as exploring the potential and actual problems, collecting all information by developing, validating, revising, conducting trials and errors of the game models for the effectiveness and efficiency of the model used. The results of the study showed from the experts of materials that at the development stage and the level of validity by the score of 3.60 which was in the highly valid by the percentage of 90.5%. From the media experts validation by the score of 3.65 which was high valid category by the percentage of 92, 55%.
Graça e heteronímia na antropologia relational de Agostinho de Hipona
Authors: Lin Davi C. Ribeiro , Dupont Anthony
Published: January 2022

This article will discuss Augustine of Hippo’s (354-430) relational horizon with a focus on grace and heteronomy in Confessions and in the Pelagian controversy. Grace and heteronomy are inserted biographically in Confessions, through an autobiographical narrative as a testimony of grace. Subsequently, grace and heteronomy would be endorsed in the polemic against the Pelagians, in which Augustine reaffirms his doctrine of original sin and the solidarity of the race in Adam, and the human need for the grace of Christ. Augustine’s anthropological perspective questions a self-centered understanding of human autonomy and emphasizes its dependence upon a relational horizon. A synthesis will be expressed through three axes: (i) heteronomy as an expression of a dramatic anthropology of search and encounter (ii) authentic autonomy as built upon the foundation of heteronomy, and therefore not opposed to human responsiveness (iii) heteronomy does not deny uniqueness or singularity butrecognizes it within a responsive relational horizon.
A questão da escravatura em Luís de Molina
Authors: Rebalde João
Published: January 2022

In De iustitia et iureLuis de Molina distinguishes between different meaningsof servitude and considers slavery to be licit ifit is practised within the framework of certain conditions. This article studies Molina's position, showing that the precise definition of the conditions under which slavery is licit allows him to limit the legal scope of this practice, to denounce the injustices of the slave trade, to claim the regulation of political and ecclesiastical power, and to frame a set of slave rights.
Fabrication and Demonstration of a 3D-printing/PDMS Integrated Microfluidic Device
Authors:   Current Affiliation: POSCO, Pohang, South Korea, Cheon Jeonghyeon , Kim Seunghyun ,   Department of Electrical and Computer Engineering, Baylor University, Waco, TX, USA
Published: January 2022

3D printing is an attractive method to fabricate microfluidic devices due to (1) its fast and simple process without specialized equipment and cleanroom environment, and (2) its capability to create complex 3D structures. Combined with Polydimethylsiloxane (PDMS), it can be used to develop various microfluidic devices taking advantage of both 3D printing and PDMS. In this paper, we investigated a Digital Light Processing (DLP) 3D printer to fabricate 3D printing/PDMS integrated microfluidic devices. We used it to fabricate both a master mold for the PDMS process and a substrate containing pneumatic ports and channels. The optimal design parameters to print a symmetrical microchannel structure were determined. We also measured the printing accuracy of taper structures as an example of its capability to fabricate complex structures. Then, we fabricated a microfluidic device by integrating a PDMS component with a 3D printed substrate. The microfluidic device operation was demonstrated using dye solutions. The fluidic control results clearly show the microfluidic device works as expected.
Development of a Pipeline for Adverse Drug Reaction Identification in Clinical Notes: Word Embedding Models and String Matching (Preprint)
Authors: Siegersma Klaske R , Evers Maxime , Bots Sophie H , Groepenhoff Floor , Appelman Yolande , Hofstra Leonard , Tulevski Igor I , Somsen G Aernout , den Ruijter Hester M , Spruit Marco , Onland-Moret N Charlotte
Published: January 2022

BACKGROUND

Knowledge about adverse drug reactions (ADRs) in the population is limited because of underreporting, which hampers surveillance and assessment of drug safety. Therefore, gathering accurate information that can be retrieved from clinical notes about the incidence of ADRs is of great relevance. However, manual labeling of these notes is time-consuming, and automatization can improve the use of free-text clinical notes for the identification of ADRs. Furthermore, tools for language processing in languages other than English are not widely available.

OBJECTIVE

The aim of this study is to design and evaluate a method for automatic extraction of medication and Adverse Drug Reaction Identification in Clinical Notes (ADRIN).

METHODS

Dutch free-text clinical notes (N=277,398) and medication registrations (N=499,435) from the Cardiology Centers of the Netherlands database were used. All clinical notes were used to develop word embedding models. Vector representations of word embedding models and string matching with a medical dictionary (Medical Dictionary for Regulatory Activities [MedDRA]) were used for identification of ADRs and medication in a test set of clinical notes that were manually labeled. Several settings, including search area and punctuation, could be adjusted in the prototype to evaluate the optimal version of the prototype.

RESULTS

The ADRIN method was evaluated using a test set of 988 clinical notes written on the stop date of a drug. Multiple versions of the prototype were evaluated for a variety of tasks. Binary classification of ADR presence achieved the highest accuracy of 0.84. Reduced search area and inclusion of punctuation improved performance, whereas incorporation of the MedDRA did not improve the performance of the pipeline.

CONCLUSIONS

The ADRIN method and prototype are effective in recognizing ADRs in Dutch clinical notes from cardiac diagnostic screening centers. Surprisingly, incorporation of the MedDRA did not result in improved identification on top of word embedding models. The implementation of the ADRIN tool may help increase the identification of ADRs, resulting in better care and saving substantial health care costs.
Inflammatory Cells in Nephrectomy Tissue from Patients without and with a History of Urinary Stone Disease
Authors: Dejban Pegah , Wilson Elena M. , Jayachandran Muthuvel , Herrera Hernandez Loren P. , Haskic Zejfa , Wellik Linda E. , Sinha Sutapa , Rule Andrew D. , Denic Aleksandar , Koo Kevin , Potretzke Aaron M. , Lieske John C.
Published: January 2022

Background and objectives

Urinary stone disease has been associated with inflammation, but the specific cell interactions that mediate events remain poorly defined. This study compared calcification and inflammatory cell patterns in kidney tissue from radical nephrectomy specimens of patients without and with a history of urinary stone disease.

Design, setting, participants, & measurements

Nontumor parenchyma of biobanked radical nephrectomy specimens from age- and sex-matched stone formers (n=44) and nonstone formers (n=82) were compared. Calcification was detected by Yasue staining and inflammatory cell populations by immunohistochemistry for CD68 (proinflammatory M1 macrophages), CD163 and CD206 (anti-inflammatory M2 macrophages), CD3 (T lymphocytes), and tryptase (mast cells). Calcifications and inflammatory cells were quantified in cortex and medulla using Image-Pro analysis software.

Results

Calcification in the medulla of stone formers was higher than in nonstone formers (P<0.001). M1 macrophages in the cortex and medulla of stone formers were greater than in nonstone formers (P<0.001), and greater in stone former medulla than stone former cortex (P=0.02). There were no differences in age, sex, body mass index, tumor characteristics (size, stage, or thrombus), vascular disease status, or eGFR between the groups. M2 macrophages, T lymphocytes, and mast cells did not differ by stone former status. There was a correlation between M1 macrophages and calcification in the medulla of stone formers (rho=0.48; P=0.001) and between M2 macrophages and calcification in the medulla of nonstone formers (rho=0.35; P=0.001). T lymphocytes were correlated with calcification in the cortex of both nonstone formers (rho=0.27; P=0.01) and stone formers (rho=0.42; P=0.004), whereas mast cells and calcification were correlated only in the cortex of stone formers (rho=0.35; P=0.02).

Conclusions

Higher medullary calcification stimulated accumulation of proinflammatory rather than anti-inflammatory macrophages in stone formers.
Anamorphoses in the representation of the ecological situation in the Russian Federation regions
Authors: Tikunov V.S. , Kotova T.V. , Kozhukhar A.Yu. , Chereshnia O.Yu.
Published: January 2022

The authors described anamorphoses for visualizing the ecological situation in the Russian Federation regions, using the pollutants total emissions in the atmosphere, the discharge of contaminated waste into surface water bodies, the production and consumption waste volume generated. This data can be laid in the foundations of the created anamorphoses or/and used as a thematic load on them as indicators calculated with various characteristics of the Russian Federation regions, and in particular
Optimization of deformation marks location at building a network in the form of a linear spatial intersection
Authors: Kornilov Yu.N. , Tsareva O.S. , Shevchenko A.S.
Published: January 2022

The authors present the assessment of determining the deformation marks’ coordinates accuracy at constructing a network in the form of a linear spatial intersection. Using the distance between the control points and deformation marks; their coordinates are defined. The root- and general mean-square errors in determining the coordinates arising from the faults in measuring the lengths and depending on the shape of the spatial intersection are calculated. Computational mistakes enable assessing the possibility of obtaining the desired results at designing a network of deformation marks with an accuracy that meets the requirements of regulatory documents, and taking the expected accuracy of linear measurements into account. Selecting the marks is shown by the example of an elementary model. Two computer programs for that purpose were developed. The convergence of the results obtained in the course of the programs and theoretical modeling indicates the correct operation of the software. The developed algorithm and pro-grams enable optimizing the location of deformation marks at designing a network.
Automated detection of agricultural land overgrowing using WorldView and Sentinel-2
Authors: Kalitka L.S.
Published: January 2022

The author considers the possibility of areas overgrowing automated determination in agricultural territory to reduce the time required to perform tasks of identifying disturbed lands and decrease the human factor influencing the result. The methodology is based on a system of converting the initial remote sensing data into a segmented image. The purpose is to achieve the highest reliability of percentage at further uncontrolled classification. The initial data is that of space survey with high and medium spatial resolution, geometric and atmospheric correction and vector boundaries of agricultural fields. The author applies the watershed method to the original images to increase the reliability of the final result. The Sobel operator is used as preprocessing method to create a gradient image. Further joining of adjacent homogeneous segments together is carried out using the Full Lambda Schedule method. The segmented image is classified through the k-means clustering technique. Materials from WorldView-3 and Sentinel-2 satellites agricultural territories in the Republic of Kalmykia and Kaluga oblast were used. The classification result is analyzed and on its basis an overgrowth vector mask of agricultural fields is created.
Analyzing the data from the website of the National Atlas of Russia, its relevance and demand
Authors: Litvinov N.Yu.
Published: January 2022

Exploring the relevance of the contents loaded in site Russian federation National atlas is considered in the article. Its attendance and the provided data’s importance for the period of the recent 7 years are analyzed. This analysis made a background for the author on renovation of the resource. During the research some foreign experience on creating printed and digital national atlases was studied. Basing on the modernization results the change in activities of the users was noted in comparison with their previous ones. The research shows that the site has been functioning for fifteen years already, and the information provided still remains relevant. Due to connecting the domain .ru the renovated resource became more easily available for foreign audience. In the period of the Russian Federation digital transformation the National atlas site (nationalatlas.ru) with its updated contents can make a part of the National spatial data system.
A HISTÓRIA CONTADA PELOS VITORIOSOS: UMA ANÁLISE DO PROGRAMA VIMVER DA FUNDAÇÃO RENOVA
Authors: Saraiva Carolina Machado , Pereira Michel Richter de Souza Oliveira
Published: January 2022

Este artigo analisa o programa Vimver (vivências no território), promovido pela Fundação Renova e tem por objetivo compreender qual é a memória construída pelo citado programam acerca da queda da barragem de Fundão, ocorrida em novembro de 2015 e que ainda hoje encontra-se prejudicando a vida de milhares de pessoas atingidas. A metodologia de pesquisa foi a qualitativa do tipo desk research, com análise de documentos referentes ao programa Vimver, desde cartilhas do programa a reportagens midiáticas sobre ele. Os dados analisados foram cotejados à luz das teorias da Sociologia do Desastre e do Dark Tourism. Os resultados apontam para a construção de uma história unidimensional, construída e narrada exclusivamente pela Fundação Renova, que acaba utilizando-se dos meios midiáticos para promoção de sua reputação e a das mineradoras controladoras e da Samarco. Ao invés de haver promoção de diálogo e controle social, a Fundação Renova oblitera os direitos dos atingidos, impedindo o acesso a informações idôneas sobre a queda da barragem de Fundão.
GEOPOLÍTICA DOS RECURSOS NATURAIS ESTRATÉGICOS E O PAPEL DO ESTADO BRASILEIRO
Authors: Dorneles Tathiane Marques , Ventura Tailiny , Almeida Luz Marina Lopes
Published: January 2022

O controle e a gestão de recursos escassos são expressões contemporâneas da geopolítica global, na qual, a apropriação e a defesa de certas riquezas constituem um alicerce para a construção de um projeto nacional de desenvolvimento. Nesta perspectiva, este trabalho busca discutir a relação entre a geopolítica dos recursos estratégicos e o papel do Estado brasileiro na articulação e defesa dos interesses nacionais. A exploração destes recursos permitiu que o país obtivesse avanços em termos de geração de tecnologia e garantiu sua inserção competitiva no mercado mundial. Entretanto, estes mesmos recursos podem ser utilizados como ferramentas coercitivas e de pressão por Estados hegemônicos e suas corporações, criando desafios à posição do Brasil quanto ao controle e uso de suas riquezas naturais. Para discutir essas questões traçamos um panorama comparativo entre o pensamento estratégico brasileiro formal e o papel efetivo do governo na defesa dos interesses nacionais.
The living roots of literary estates
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Bogdanova Olga A.
Published: January 2022

The preface reveals the conceptual basis of the collective monograph “Estate real — estate literary: vectors of creative transformation” — the 6th issue of the scientific book series “Russian estate in a global context”, and also provides an overview and analysis of the topics and problems of its sections and the articles contained therein. Promising areas of further work within the series are outlined.
Jukovsky’s Orekhovo estate: “feeding landscape” and museum reality (based on E.R. Dombrovskaya’s “Sighs of the chained. Russian saga”)
Authors:   Ural Federal University named after the first President of Russia B.N. Yeltsin, Prashcheruk Natalia V.
Published: January 2022

The work provides an analysis of the “estate topos”, unveiled through the main plot related to a history of an old Russian family in the novel “Sighs of the chained. Russian saga” (2017) by a contemporary writer Ekaterina Dombrovskaya. The image of the Orekhovo estate is built in the context of the author’s Christian worldview and in relation to the understanding of the genus as a phenomenon in its spiritual and ontological foundations, as well as with the ideas of “signal heredity” by M.E. Lobashev and “feeding landscape” by L.N. Gumilev, opposite to the “barrack landscape”. Writer’s interpretation of events and characters’ fates is based on evangelical and patristical tradition as well as on biblical and general cultural symbols. The key symbols of the novel are “deep waters” that feed life of a family and its ancestral memory and oppose the “coffin of oblivion”. Narration is characterized by a broad range of discourses, profusion of means of expression and different literary styles all of which add to an artistic completeness of the “estate topos”. The joy of embracing the nativeness is combimed with a dramatic experience of realizing that this nativeness is lost and can not be restored. Preserving the past is only possible by keeping the memory of it.
On the Concept of Petersburg “Dacha Folklore” of the late 19th – early 20th century
Authors:   University of Viterbo, Mari Emilio
Published: January 2022

The aim of this paper is to analyse the relation between orality and literacy in some of the expressive forms linked to the suburban summer leisure during Saint Petersburg “Belle Époque”. In particular, I will consider a forgotten corpus of texts and practices, somehow halfway between folklore and literature, cultural production and consumption, that mirrored and filled free time in dacha settlements, allowing the encounter between different socio-cultural realities (summer dwellers and “natives”) and contributing in many ways to the weakening of the boundaries between the “elitist” and the “popular” in the artistic culture of the time. The analysis of these materials, despite their aesthetic marginality, gives us a new vision “from the bottom up” of the pre-revolutionary dacha culture: a rapidly modernising landscape in which still fluid social bodies meet and fight in order to obtain their “right to the city”.