bluuebunny/crossref_metadata_2025 huggingface dataset:
A review on high-throughput development of high-entropy alloys by combinatorial methods
Authors: Mooraj Shahryar , Chen Wen
Published: March 2023

High-entropy alloys (HEAs) are an emerging class of alloys with multi-principal elements that greatly expands the compositional space for advanced alloy design. Besides chemistry, processing history can also affect the phase and microstructure formation in HEAs. The number of possible alloy compositions and processing paths gives rise to enormous material design space, which makes it challenging to explore by traditional trial-and-error approaches. This review highlights the progress in combinatorial high-throughput studies towards rapid prediction, manufacturing, and characterization of promising HEA compositions. This review begins with an introduction to HEAs and their unique properties. Then, this review describes high-throughput computational methods such as machine learning that can predict desired alloy compositions from hundreds or even thousands of candidates. The next section of this review presents advances in combinatorial synthesis of material libraries by additive manufacturing for efficient development of high-performance HEAs at bulk scale. The final section of this review discusses the high-throughput characterization techniques that are used to accelerate the material property measurements for systematic understanding of the composition-processing-structure-property relationships in combinatorial HEA libraries.
Potential of Bacillus sp. from Kebun Raya Liwa as a Producer of Indole Acetic Acid (IAA) Hormone
Authors:   Universitas Lampung, Athfin Fadlina , Handayani Kusuma , Setiawan Wawan A. , Ekowati C. Nugroho
Published: March 2023

Kebun Raya Liwa’s soil has the potential to allow for a population of microorganisms such as the Bacillus sp. Bacillus sp. Kebun Raya Liwa are known to produce phytohormones that have the potential to help plant growth and development, one of which is the hormone Indole Acetic Acid (IAA). This study aims to determine the potential of Bacillus sp. from the soil of Kebun Rawa Liwa in producing IAA hormones. The research method included taking soil samples, preparing Nutrient Agar (NA) medium, measuring soil pH samples, isolating soil bacteria, purifying and characterizing Bacillus sp., preparing IAA standard curves, and testing the potency of Bacillus sp. IAA production was carried out in two ways, namely measuring the content of IAA with the addition of tryptophan and without the addition of tryptophan. IAA concentration was measured using a spectrophotometer with a wavelength of 520 nm. The data obtained is presented in tabular form. The isolation results obtained 10 isolates that were able to produce IAA hormone with and without tryptophan. The highest IAA production without tryptophan was isolate BP 5 with a concentration of 1.18 ppm, and the isolate that was able to produce the highest IAA with tryptophan was isolate BP 13 with a concentration of 3.90 ppm. This indicates that the isolate Bacillus sp. from the soil rhizosphere Kebun Raya Liwa can produce IAA hormones.
Production of Resistant Starch from Avocado Seeds (Persea americana) through Streptomyces sp. AB8 Fermentation and Autoclaving-Cooling Variations
Authors:   Universitas Lampung, Arifiyanto Achmad , Inah Siti , Ningsih Indah Sukma , Ekowati Christina Nugroho , Handayani undjung Tripeni
Published: March 2023

Agricultural waste with a high starch content potentially serves as a source of resistant starch. The avocado seed has not been explored much and is often thrown away as waste in consuming avocados. Resistant starch has properties and functions as dietary fiber and has advantages as a prebiotic. This study aims to determine the effect of fermentation treatment using Streptomyces sp. AB 8 and variations in the number of pressure-cooling heating cycles to increase avocado seed-resistant starch. The research phase consisted of pre-treating the avocado seeds and fermentation by Streptomyces sp. AB 8 followed by a pressure heating-cooling stage with 0, 1, 2, and 3 cycles. Concerning modified starch, this study also measured levels of starch, amylose, amylopectin, and resistant starch. Digestion test using Lactobacillus sp. by viewing the clear zone around the colonies after 48 hours to evaluate the digestibility of resistant starch. The results of this study indicate that the fermentation treatment by Streptomyces sp. AB 8 and pressure-cooling heating can increase the levels of resistant starch in avocado seeds. Fermentation treatment with two cycles of heating-pressure-cooling (S1) produced the best resistant starch content of 7.51% and had the highest enzymatic index of 2.48 ± 0.45.
Determinación de ciclos de conducción de camiones y emisiones contaminantes
Authors:   Universidad Autónoma de Querétaro, Salazar Sabas Oscar Alejandro , Betanzo Quezada Eduardo ,   Universidad Autónoma de Querétaro
Published: March 2023

El transporte de carga urbano es un importante contribuidor de emisiones contaminantes en las ciudades. Una brecha actual en la investigación orientada a la evaluación de emisiones móviles en México es la falta de ciclos de conducción representativos del transporte de carga. Por lo tanto, el objetivo de esta investigación fue desarrollar un ciclo de conducción para vehículos ligeros de carga y compararlo con ciclos internacionales de referencia. La técnica de persecución de vehículo fue usada para recolectar datos de velocidad y posicionamiento geográfico a través de 37 recorridos dentro de la zona de monumentos históricos de Querétaro. Una metodología que combina análisis de componentes principales, conglomerados por el método de k-medias y el modelo de la cadena de Markov, fue utilizada para la construcción de los ciclos candidatos. Los resultados muestran que, en comparación con el ciclo obtenido, los ciclos de conducción de referencia internacionales aplicados en México, subestiman contaminantes como NOx y CO por más del 22 y 48 %, para el Nuevo Ciclo Europeo de Conducción y el Procedimiento de Ensayo Federal 75, respectivamente. Esto refleja que el proceso de construcción de ciclos de conducción debe considerar las diferentes clases vehiculares y sistemas de transporte, ya que cada uno tiene patrones únicos de manejo, lo cual da como resultado ciclos de conducción significativamente diferentes.
Preliminary Data: Feeding and Colon Cancer Growth. Modified Nitrogen Intake Leads to Blunted Cancer Growth Independently by Serine
Authors: Corsetti Giovanni , Romano Claudia , Scarabelli Tiziano Maria , Chen-Scarabelli Carol , Pasini Evasio , Dioguardi Francesco Saverio
Published: March 2023

Cancer cells are originated by normal cells and with those share the need to be fed. Metabolic reprogramming in cancer cells is not yet fully understood, and there is a vast literature suggesting that any macronutrient may be efficiently utilized by cancer for duplication purposes. Metabolic hyperactivity of cancer and continuous duplication requires huge amounts of both energy and substrates for syntheses of components of new cells, and the modifications of metabolism induced by cancer cells to survive and grow damaging lethally, the whole organism. In rodents, we have recently observed that by modifying diet in a way not existent in nature, changing radically the ratios among essential and non-essential amino acids (AA) (usually less than 0.9), largely increasing essential-AA (EAA) percentages, lifespans increased. In vitro, EAA supplementation promoted colon cancer cells (CT116) apoptosis by enhanced autophagy. Therefore, we tested in mice if injection of colon cancer cells would have been followed by unvaried development of cancer volumes in animals fed with standard laboratory diet (controls) versus EAA rich modified diets (EAAmd). Both diets perfectly matched the same total macronutrients and micronutrients contents; only quality of nitrogen was radically different. Results of the first set of 8 animals, 4 controls and 4 EAAmd-fed, showed that controls develop cancers near 5 times larger and heavier than EAAmd-fed (P<0,002) on the same time. We discuss which epigenetic modifications would be involved and worth to be studied, and what kind of scenarios those preliminary findings, if confirmed, would open.
ANALISIS DAMPAK KEGIATAN PERTAMBANGAN EMAS TERHADAP LINGKUNGAN FISIK DI DESA PANINGKABAN KECAMATAN GUMELAR KABUPATEN BANYUMAS TAHUN 2021
Authors: Hasanah Umi Nur
Published: March 2023

Penelitian ini bertujuan untuk mengetahui proses kegiatan pertambangan emas dan dampak kegiatan pertambangan emas terhadap kondisi lingkungan fisik di Desa Paningkaban Kecamatan Gumelar di Kabupaten Banyumas. Metode penelitian yang digunakan adalah deskriptif kualitatif dengan teknik pengumpulan data berupa observasi terhadap kondisi pertambangan serta dampaknya yang didukung dengan hasil wawancara dan dokumentasi yang dilakukan dilapangan. Hasil penelitian menunjukan bahwa proses pertambangan masih menggunakan cara tradisional dengan cara melakukan pembuatan lubang/sumur menggunakan alat sederhana, pengambilan bahan galian tanpa mesin, pemisahan dan penghalusan serta penggilingan secara manual, penyaringan tanpa pengamanan ketat yang langsung terkontaminasi dengan manusia, hingga proses ekstrasi dengan cara pembakaran. Kondisi tersebut menimbulkan dampak perubahan yang terjadi disekitar lokasi pertambangan emas, diantaranya adalah penggunaan lahan dari perkebunan menjadi unit pengolahan emas yang berpengaruh terhadap kondisi tanah dan vegetasi, menyebabkan terjadinya amblesan disekitar unit pengolahan emas, pencemaran tanah dilingkungan permukiman, serta pencemaran air sungai dan sumur warga akibat pembuangan limbah merkuri karena tempat penampungan sudah tidak mampu untuk menampung limbah yang dihasilkan.
INTEGRASI MATERI KEBENCANAAN PADA JENJANG SEKOLAH DASAR DI KECAMATAN NGARGOYOSO, JAWA TENGAH
Authors: Ammelia Inge , Lestari Diyah Sri , Al Ghazy Ghulam Tsabat , Wibowo Yunus Aris
Published: March 2023

Karanganyar is an area that is prone to landslides, one of which is in Berjo Village, Ngargoyoso District. Educational integration is an effort to unify the process of changing one's attitudes and behavior in the eyes of the group in an effort to mature humans through learning. This study aims to determine the integration of disaster materials and educators' perceptions of each elementary school in landslide-prone areas, Ngargoyoso District. The approach used in this study is a quantitative approach using primary data through questionnaires and interviews. The sample technique used in this study used a purposive sampling technique with a research sample of 20 people divided into 16 teachers and 4 principals or 4 teachers and 1 principal at SD N 1 Kemuning, SD N 4 Kemuning, SD N 5 Kemuning, and SD IT Al-Hikmah. In this study, the importance of a teacher's perception of understanding disaster material to support efforts to reduce disaster risk and make fixed procedures for disaster preparedness in schools. The existence of educational knowledge in schools is expected to be an effective measure for the distribution of information regarding the integration of disaster materials.
 
Keywords: Disaster, Materials, Integration
ANALISIS RESILIENSI KOMUNITAS SAMIN DAN MASYARAKAT SEKITAR KECAMATAN BANJAREJO DALAM MENGHADAPI KEKERINGAN TAHUN 2020
Authors: Sari Meylita Diah Anggita , Yusup Yasin , Ajar Seno Budhi
Published: March 2023

The Samin community has local wisdom related to drought disaster management. The areas studied in this research are Klopoduwur Village and Sendanggayam Village, with the research objectives (1) to determine the resilience of the samin community and the community around the Banjarejo sub-district, (2) to determine the resilience level of the samin community and the surrounding community in Banjarejo sub-district. The research design used qualitative analysis using the methods of observation, interviews, and documentation with data-flow model analysis techniques. The population in this study is the community in Banjarejo District by taking samples using purposive sampling. The results showed that the resilience of the samin community and the community outside of the samin in Banjarejo District to drought disasters had medium and high resilience with absorption, adaptive, and transformative capacities applied before the drought occurred. While the form of the resilience of the samin community in Klopoduwur Village and people outside the samin community in Sendaggayam Village, Banjarejo District, against drought disasters in the form of social systems, ecological systems, and socio-ecological systems.
INTEGRASI LAYANAN INFORMASI DALAM MENINGKATKAN KAPASITAS PEMAHAMAN MAHASISWA MENGHADAPI BENCANA ALAM
Authors: Nakhma’Ussolikhah  , Ficky Adi Kurniawan
Published: March 2023

The situation and condition of the universe has a great influence on individual attitudes and environmental changes. Failure to create environmental friendliness can be seen from unstable natural conditions such as floods, earthquakes, landslides. This change is caused by a lack of awareness, low environmental care from individuals, and the surrounding community. The purpose of this study is to provide students with an understanding of the causes of natural disasters, how to respond appropriately so as not to harm the community when natural disasters occur as part of preventive measures through the provision of information services. This research uses qualitative-descriptive method. Interview data collection techniques and documentation. the main informants consisted of 4 5th semester students and 2 BKPI lecturers supporting informants. The research results obtained from interviews with BKPI students in semester 5 include their self-understanding of natural disaster situations that have not been able to be handled properly. This cause becomes a joint evaluation of the community, students, and the local government to prioritize the provision of disaster preparedness information services. Information services have an important role in increasing knowledge and self-understanding for each individual to respond to disaster situations with stable emotional conditions, minimizing anxiety levels and being able to adapt well to adaptation in the post-disaster environment.
IDENTIFIKASI ZONA BAHAYA GEMPA BUMI BERDASARKAN PERCEPATAN TANAH MAKSIMUM DI KOTA SEMARANG
Authors: Koesuma Sorja , Fajrin Viola , Sunardi Bambang
Published: March 2023

Semarang City as the Capital of Central Java Province requires an earthquake-prone map. It is required since there are two active faults in Semarang, namely the Semarang fault (part of the Baribis - Kendeng fault) and the Ungaran fault. Moreover, Semarang City is composed of alluvial layers that can accelerate earthquake waves. This study aims to determine site class, peak ground acceleration (PGA) in bedrock, PGA at ground level and earthquake hazard index in Semarang City. In this study, the calculation of peak ground acceleration uses the method in SNI 1726: 2019, while the earthquake hazard index refers to the JICA classification. As input data in the form of the peak ground acceleration value in bedrock, the average shear wave velocity to a depth of 30 meters (Vs30) to determine the site class, as well as the value of the amplification factor. The calculation results in almost all areas of Semarang City have a high earthquake hazard index and only Genuk sub-district has a moderate hazard index. The main determinants of peak ground acceleration at the surface are the source of the earthquake and the rock type
STUDI KESIAPAN MAGANG INDUSTRI (MI) MAHASISWA PROGRAM STUDI PENDIDIKAN TEKNIK MESIN FKIP UNS
Authors: Rohman Ngatou , Saputro Herman
Published: March 2023

The FKIP UNS Mechanical Engineering Education study program is one of the clusters in vocational education that produces vocational teacher candidates. To equip the competencies required to become a SMK teacher in the field of Mechanical Engineering and Automotive Engineering, it is necessary to gain experience in the industry. Industrial Internship is one of the subjects that must be taken by students of the Mechanical Engineering Education Study Program FKIP UNS as a graduation requirement. To examine the extent to which students carry out industrial apprenticeship programs in terms of the aspects of students and study programs, it is necessary to conduct research on the analysis of Industrial Internship readiness of students of the Mechanical Engineering Education Study Program FKIP UNS which can then be used as a basis for making policies regarding industrial apprenticeships. The design in this research is descriptive quantitative. The data collection technique was carried out in a survey using a questionnaire. The respondents in this study were all students of the Mechanical Engineering Education Study Program FKIP UNS class of 2020 or semester IV who will carry out the Industrial Internship program in 2022. The research data were analyzed descriptively with the help of the SPSS program. The results showed that 1) the readiness for industrial internships for students of the Mechanical Engineering Education Study Program FKIP UNS class of 2020 was 3.93 which was in the good category. 2) in providing industrial apprenticeship services for students, the Mechanical Engineering Education study program FKIP UNS makes an industrial apprentice manual and appoints an industrial apprentice coordinator.
Analysis of Misconceptions in View of Gender Differences in Chemistry Learning
Authors: Kristyasari Marantika Lia , Kusumaningrum Idha Ayu
Published: March 2023

Misconceptions refer to students' incorrect understanding of a concept, which can lead to difficulties in problem-solving activities. This study aimed to examine the misconceptions of high school students regarding gender differences. The research was conducted in a selected high school, using a purposive sampling technique to select a class with above-average academic achievement. The research used a quantitative descriptive method and analyzed the data using GRM scoring. The findings showed that the average percentage of misconceptions held by students in all competency indicators was 28% for females and 22% for males. Misconceptions were found in all four competency indicators for buffer solution materials, including explaining the meaning of components, the working principle of buffer solutions, the role of buffer solutions in everyday life, and calculating the pH of buffer solutions. The highest percentage of misconceptions for both females and males was found in the first competency indicator, with 47% and 56%, respectively.
Summative Assessment Using Moodle Learning Management System in Vocational High School: Teacher Perspective
Authors: Kustiaman Aditya Irfan , Wahyudin Dinn , Dewi Laksmi
Published: March 2023

This study used a qualitative approach using descriptive methods. The research site was conducted at Cimahi City Center for Excellence Vocational High School (Center of Excellence) with teacher research participants in the curriculum and subject teachers involved as supervisors in implementing summative assessments. Data collection is conducted by conducting interviews and documentation studies on learning management systems owned by schools. The validity and reliability of the research results are checked using triangulation of data and information. As a result of the study, summative assessments using LMS Moodle were more effective over time, reduced paper usage was easy to use, and encouraged mastering technology competencies for teachers. The negative impact of using LMS Moodle on summative assessment is the student's chances of finding answers online. Anticipation can be achieved by adding a blocking feature to Moodle. LMS Moodle-based facilities and facilities support facilities are the main prerequisites for the smooth implementation of summative assessments.
Ecological Intelligence in Local Wisdom of The Tengger Tribe as Learning Sources of Social Studies
Authors: Sunarno Ali , Supriatna Nana
Published: March 2023

The Tengger tribe has local wisdom as a form of ecological intelligence in minimizing natural damage. Local wisdom is important to be bequeathed to the next generation, but the current globalization hampers the process of inheriting these values. Education, in this case, Social Studies subjects, is heavily responsible for internalizing these noble values. This article was written based on the results of a qualitative descriptive study that explored the potential of the local wisdom of the Tengger people related to ecological intelligence. Based on the research results, the people of the Tengger Tribe have wisdom in managing land, forests/trees, and water. Local wisdom, a form of ecological intelligence, can be adopted as a Social Studies learning resource in junior high schools in the Merdeka Curriculum. The research results are expected to be used as a reference in developing Social Studies learning based on local culture.
Trapezoid Stress Fracture in an Olympic-Level Gymnast
Authors: Bertha Nicholas M. , Wisinski Jeffrey J. , Taylor Kenneth F.
Published: March 2023

Case:

A 23-year-old elite-level gymnast presented with insidious-onset pain near the base of the second metacarpal. The patient was found to have a trapezoid stress fracture and was treated nonoperatively in a thumb spica cast for 4 weeks. He resumed gymnastics without limitations 8 weeks from the time of diagnosis.

Conclusion:

Trapezoid stress fractures must be considered when evaluating patients presenting with pain about the base of the index finger metacarpal, particularly those who perform activities that repetitively place high loads across the wrist. Wrist immobilization and a supervised return to participation resulted in an excellent outcome for this patient.
Adductor Branch of Terminal Divisions of the Ulnar Nerve Transfer to the Thenar Motor Branch in a High Median Nerve Palsy
Authors: Jerome J. Terrence Jose
Published: March 2023

Case:

The author reports a 4-month-old high median nerve palsy in a 19-year-old man with right forearm fractures, stabilized with dynamic compression plates and screws. Surgical exploration revealed a large median nerve neuroma in the midarm that was excised, and the gap was bridged with sural nerve cable grafts. The extensor carpi radialis nerve was transferred to the anterior interosseous nerve in the forearm. The adductor branch of terminal divisions of the ulnar nerve was transferred to the thenar branch of the median nerve in the hand.

Conclusions:

The adductor branch of ulnar nerve transfer to the thenar motor branch in high median nerve palsy efficiently restored thumb opposition in 10 months of follow-up. In addition, the patient's grasp and pinch improved, preserving thumb adduction.
Irreducible Posterolateral Knee Dislocation
Authors: Pache Santiago , Vázquez José María , Chahla Jorge , Moatshe Gilbert , LaPrade Robert F.
Published: March 2023

Case:

A 62-year-old male patient suffered an irreducible posterolateral knee dislocation after a horse fell on him. The left knee was slightly flexed with a medial dimple sign present. The medial retinaculum, medial patellofemoral ligament, posteromedial corner structures, and vastus medialis obliquus (VMO) muscle were incarcerated in the medial joint. An open reduction and the medial retinaculum and VMO gap were repaired, and the knee was stabilized in an external fixator for 4 weeks. At 32-month follow-up, the patient had almost full knee motion and good subjective outcomes with moderate residual joint laxity.

Conclusion:

Early clinical diagnosis of irreducible knee dislocations and emergent open reduction should be performed to reduce the risk of soft-tissue compromise.
Contenidos web y percepciones sociales: la imagen proyectada del paisaje cultural de Constantina (Sevilla, España)
Authors: Fernández Cacho Silvia , Durán Salado Isabel
Published: March 2023

Este trabajo tiene como finalidad principal la presentación de una propuesta metodológica de aproximación a la percepción paisajística a través del análisis de la imagen proyectada por los agentes sociales en los contenidos que publican en páginas web. Esta propuesta podría aplicarse tanto para obtener una información previa al despliegue de técnicas etnográficas tradicionales (entrevistas, encuestas, grupos focales, etc.) como para sustituir dicho despliegue cuando no sea posible realizarlo por falta de los recursos necesarios o por la existencia de un contexto que lo imposibilite como la escala de la investigación, el confinamiento social o la inestabilidad socio-política. La aplicación de técnicas cuantitativas y cualitativas para el análisis de contenidos web permitirá evaluar el alcance de esta propuesta y su capacidad para complementar, validar o contradecir el conocimiento científico-técnico generado sin el concurso de los agentes sociales.
La percepción del cambio climático en espacios insulares: el caso de Tenerife
Authors: Correa González Jordan , López Díez Abel , Dorta Antequera Pedro , Martín Raya Nerea
Published: March 2023

En el contexto del actual cambio climático, resulta prioritario vehicular mecanismos que faciliten la integración de la perspectiva ciudadana en la lucha contra este fenómeno. Organismos como el IPCC han puesto de manifiesto la importancia de atender, en la inexorable transición que se avecina, a la percepción y a las experiencias de la población como fuentes de información complementarias a las evidencias científicas. Además, resulta de interés comprobar la valoración de la actuación institucional al respecto y el grado de concienciación social ante este reto global. De este modo, el presente trabajo, basándose en una amplia encuesta realizada en la isla de Tenerife (Canarias), analiza la percepción de la población residente sobre las causas y efectos del cambio climático, así como su compromiso medioambiental y el conocimiento de las iniciativas gubernamentales de mitigación y adaptación. Se observa un alto grado de preocupación sobre la cuestión entre la ciudadanía, que apoya la existencia del cambio climático, manifiesta saber en qué consiste y valora de manera negativa, por lo general, la actuación de las administraciones públicas, desconociendo, además, las iniciativas aprobadas.
Pizza Truck
Authors:   , Antón Reyes Rosendo Jesús , Castro Lucas Andrés Alonso
Published: March 2023

El presente Plan de negocio comprueba la viabilidad del proyecto “Pizza Truck” la cual es una empresa dedicada a la elaboración y comercialización de pizzas en diferentes formas y presentaciones Personales. Ofreciendo a los clientes una alternativa atractiva, confiable y rápida, para aquellas personas que lleven un ritmo de vida acelerado y frecuentemente coman fuera de sus hogares, abarcando 3 distritos de lima metropolitana que son Chorrillos, Barranco y Surquillo, pertenecientes NSE B. En los siguientes capítulos contempla la aplicación de diversos planes referidos al marketing, procesos, a los recursos humanos y las finanzas. Cada uno de los capítulos se recaudó información confiable y precisa para el correcto análisis e interpretación. Para llegar al cliente final se utilizará una modalidad diferente y creativa como lo es un Food Truck, asimismo esta es una fortaleza para trasladarse persiguiendo zonas calientes que quiere decir alta convocatoria de público. De acorde con un correcto plan financiero, primero se establece la inversión requerida del proyecto la cual es de S/35,490.9. Luego, encontrar el financiamiento idóneo para el proyecto y posteriormente elaborar el estado de situación financiera del negocio, el estado de resultados, el flujo de caja, entre otros. Así mismo, para los 5 años de proyectado el negocio mediante herramientas financieras dieron como consecuencia un TIR de 407%. y VAN de S/2015973.14. Por lo que con dichas cifras se puede demostrar que el proyecto es viable. Finalmente, se presentan las respectivas conclusiones y recomendaciones, la cual pone en evidencia que la ejecución del proyecto es atractiva, rentable para los 5 años de proyectado el trabajo de investigación.
Plan de negocio para crear una empresa de asesoramiento contable
Authors:   , Pérez Arteaga German Enrique
Published: March 2023

El Plan de Negocios que seguidamente se presenta ha sido planteado con el propósito de crear una empresa de asesoramiento contable, la cual se establecerá en la ciudad de Lima – Perú, siendo de gran potencial por los servicios que ofrecerá y cobertura geográfica. Mediante este trabajo se establecerá la viabilidad financiera del plan, en otras palabras, este estudio logrará establecer las ganancias que se generarán a mediano o largo plazo. Sin embargo, el presente plan no solo involucra el análisis económico-financiero, sino que igualmente contiene un estudio de los recursos materiales y humanos necesarios para ejecutar el proyecto. Durante el adelanto del presente plan se valora la idea desde diversas perspectivas, identificándose para ello: Plan estratégico; Plan de Marketing; Plan de operaciones; Plan de recursos Humanos; Plan financiero. Cada plan representa un capítulo, en el capítulo I denominado Descripción de la empresa se realiza un análisis del mercado general y local, además de estudiar el entorno de la empresa, también se agrega un capítulo 7 en el cual se describen los perfiles del equipo gerencial, que por ser nueva la compañía, se presentará un perfil del equipo de socios que conforman en grupo de emprendedores generadores de este plan de negocios. Los capítulos del dos al seis se desarrollaron bajo el modelo presentado por Weinberger (2009), examinando las variables que integran cada fase del Modelo y en el capítulo dos es formulado el plan estratégico de la Empresa, haciendo énfasis en los objetivos planteados.
Efectos de la contaminación por metales pesados
Authors:   , Elguera Limaylla Johan Manuel
Published: March 2023

La contaminación del suelo por metales es un fenómeno que se puede dar de dos formas, una de ellas de forma natural ocasionada por la degradación de las propias rocas madres donde se ha formado el suelo, de la lixiviación de metales y de la actividad volcánica; y la otra es de forma antropogénica originada del sector minero por la fundición y explotación de metales, lodos, insumos agrícolas, sedimentos residuales, combustión del petróleo y la mala disposición de desechos industriales. En los microorganismos, plantas y suelos, lo metales pesados tienden a bioaculumarse provocando el aumento de su grado de toxicidad. En el suelo puede llegar a provocar la pérdida de sus propiedades físico-químicas, incluso puede llegar a perder su fertilidad; en cuanto a los microorganismos entran a la cadena trófica con un alto nivel de concentración al igual que las plantas, provocando efectos en la salud de los seres humanos y animales, enfermedades tales como el cáncer o afecciones al sistema neurológico. Debido a esto se desarrollaron alternativas de solución con el uso de microorganismos, hongos (biorremediación) y plantas (fitorremediación) siendo la más económico y eficiente respectivamente.
Correlación entre límites políticos y bordes urbanos entre distritos: caso de estudio Villa El Salvador y Lurin
Authors:   , Avalos La Rosa Rosmery Milagros , Choquehuanca Tacusi Claudia , De los Santos Clavo Ellla Lizeth , Huamán Carrero Jeferson Michael , Mendoza Flores Lizbeth
Published: March 2023

El presente artículo está basado en la “Correlación entre límites políticos y bordes urbanos entre distritos villa el salvador y Lurín”. El desarrollo y proceso del estudio, está sustentado por un análisis en la Av. Lima, y sus alrededores (la urbanización Portales de Pachacamac de V.E.S y Villa Alejandro de Lurín), se analizó las características físicas del límite político, de la misma manera se analizó comparativamente con las características de un borde urbano, a través de conceptos, teorías, normativa; Por último, este estudio se realizó mediante cuadros de lista de cotejo tanto para el Limite y borde urbano, en el área de estudio.
Frecuencia bacteriana y patrón de resistencia a antimicrobianos (fenotipo y genotipo) en muestras de nasofaringe y manos en pacientes de UCI en el Hospital Nacional Dos de Mayo en abril 2018
Authors:   , Herrera Guzmán Adriana María , Vallejos Romero Yahira Ingrid
Published: March 2023

Objetivos: Determinar la frecuencia, perfil fenotípico de resistencia y caracterización molecular de genes de resistencia a betalactámicos y carbapenémicos en aislados clínicos obtenidos en una Unidad de Cuidados Intensivos (UCI) en Lima, Perú. Materiales y métodos: Estudio transversal para determinar la frecuencia de pacientes colonizados con potenciales patógenos. Se incluyeron hisopados de nasofaringe y manos de pacientes internados en la UCI del Hospital Nacional 2 de Mayo. La información clínica se obtuvo de las historias clínicas previamente recolectadas. En las bacterias aisladas, se evaluó la sensibilidad a antimicromianos con método de difusión en disco y se evaluaron los niveles de sensibilidad a Colistina por microdilución. Se identificó las cepas productoras de betalactamasas de espectro extendido (BLEE) mediante técnica de sinergia de doble disco. Los genes codificantes para betalactamasas y carbapenemasas se detectaron mediante el uso PCR y posterior secuenciación. Resultados: Un total de 21(95%) pacientes presentaron algún patógeno potencial en una de sus muestras. Se aislaron un total de 39 bacterias, siendo Escherichia coli la más frecuente (15, 38%). En 8 (38%) pacientes encontramos cepas multidrogoresistentes; De estos, 5 (23%) pacientes con presencia de bacterias MDR (4 E.coli y 1 P.aeruginosa) y 3 (14%) con bacterias extremadamente resistentes (XDR) (K.aerogenes, P.aeruginosa y S.marcesens). Los pacientes colonizados con cepas multidrogoresistentes presentaban una media mayor de días en UCI comparado con los pacientes que tenían cepas sensibles, 14.4 IC95% (10.05%-18.7%) vs 6.5 IC95% (2.38%-10.61) (p=0.01). Se detectaron 4 pacientes con presencia de E.coli con el mismo patrón de resistencia productora de BLEE y 2 con el gen blaCTX-M-15. En 3 P.aeruginosa de 2 pacientes se encontró el gen blaIMP y destacar la presencia en un paciente colonizado con S.marcesens con 2 genes carbapenemasas (blaKPC y blaNDM).
La gestión de compras y su influencia en la rentabilidad de la constructora Novo Home SAC, San Borja, Lima - 2019
Authors:   , Román Ramírez Lucibel Gaselita
Published: March 2023

Con este trabajo investigativo se pretendió determinar la influencia de la gestión de compras en la rentabilidad de la Constructora Novo Home SAC, San Borja, Lima – 2019. El análisis planteado en la metodología es aplicado, con un diseño transversal no experimental y un nivel descriptivo explicativo causal, mientras que la metodología considerada fue el método hipotético-deductivo; 40 empleados del área de gestión de compras llegaron a constituir la población, mientras que solo 40 de los mismos conformaron la muestra siendo utilizado un tipo de muestreo censal. Después del procesamiento y la interpretación de información, pudo evidenciarse una considerable correlación positiva de 0.772 entre la gestión de compras y la rentabilidad con un nivel de significancia inferior al 0.05 trazada en el estudio, así mismo, se determinó que la rentabilidad se halla expuesta en un 59.7% por la gestión de compras realizada en la organización. De esa manera, se posibilita la refutación de la H0 y, con ello, la aprobación de la H1; de manera se ha confirmado que la gestión de compras influye de forma significativa en la rentabilidad de la compañía Constructora Novo Home SAC
Estudio comparativo sobre del efecto saciante de las dietas de bajo índice glucémico y dieta hipocalórica moderada en mujeres entre 25 a 40 años con sobrepeso u obesidad
Authors:   , Gordon Acevedo Claudia Elena
Published: March 2023

Introducción: El exceso de peso es un problema de salud pública mundial que se encuentra en aumento. La dieta hipocalórica moderada es el tratamiento nutricional actualmente más aceptado y utilizado; sin embargo, la falta de adherencia muchas veces presentada, incentiva la búsqueda alternativas eficaces de tratamiento. Objetivo: Evaluar la efectividad sobre la saciedad de una dieta de bajo índice glicémico en comparación a una dieta hipocalórica moderada en el tratamiento del exceso de peso. Materiales y métodos: El estudio consistió en un diseño experimental cualitativo, incluyó 20 mujeres sanas, con edades entre 25 y 40 años; con sobrepeso de grado II y obesidad de grado I y grado II, que se sometieron durante 4 semanas a tratamiento nutricional dividas aleatoriamente en 2 grupos (Dieta Hipocalórica moderada y Dieta de Bajo índice glicémico). La percepción de saciedad, la adherencia al plan nutricional y la variación de peso se evaluaron diaria y semanalmente de forma respectiva. Resultados: La dieta de Bajo índice glicémico genera una mayor saciedad (p=0,025) y adherencia al tratamiento nutricional (p=0,170) en comparación a la dieta Hipocalórica moderada; sin embargo, esta última logra una reducción de peso mayor (p=0,041). Conclusiones: La dieta de Bajo índice glicémico puede ser una alternativa terapéutica en aquellos pacientes que presentan un fracaso en el tratamiento nutricional convencional por falta de adherencia a la dieta derivada de la ausencia de saciedad.
Increasing coverage and uptake of voluntary family planning in urban areas of central-eastern Uganda: an implementation research study protocol
Authors: Kananura Rornald Muhumuza , Birabwa Catherine , Ssanyu Jacquellyn Nambi , Kizito Felix , Kagaha Alexander , Namutanba Sarah , Kyangwa Moses , Kakaire Othman , Waiswa Peter
Published: March 2023

Introduction
While urban areas are often perceived and reported as better off due to the wide availability of and apparent proximity to services, family planning (FP) access among the marginalized communities such as slums might be worse. Although evidence on access to FP in urban space is illusive, just like rural poor, the urban poor residents are characterized by multidimensional challenges that not only limit the population from accessing voluntary FP (VFP) services but also expose them to unplanned sexual intercourse and ultimately unplanned pregnancies and other related consequences. In this study we seek to augment and strengthen existing efforts towards increasing coverage and uptake of VFP in Jinja city and Iganga Municipality, central eastern Uganda. Our primary question is “what interventions can effectively be packaged and delivered to increase uptake of VFP and promote urban thriving.
Methods
We propose to use the Human-Centered Design (HCD) approach to understand the needs, capabilities and challenges of users and ensure stakeholder engagement in the development or adaptation of solutions and design of programs through co-creation. As such, we shall implement in three faceted phases: formative assessment, design and implementation, implementation monitoring and evaluation. Monitoring, learning, and adaptation are embedded within the implementation process with the focus of using the information to guide implementation design and learning. Building on implementation research framework such as RE-AIM (reach, effectiveness, adoption, implementation, maintenance) and Fidelity frameworks, we shall apply process monitoring and evaluation approach to address questions related to what package of FP interventions work, for whom, under what circumstances and why.
Discussion
Guided by a strong learning and implementation flexibility, we hypothesize that our implementation will provide the segmentation specific high impact interventions in an urban context. We also hypothesize that the use human-centred approach will enable us to develop a tailored package of FP interventions that match different segments in an urban setting of developing countries.
Design an Efficient FPGA Based Hardware Implementation for Real-Time Mobile Epileptic Seizure Prediction Using Deep Neural Network
Authors: SAMANTA ANU , Hatai Indranil , Mal Ashis Kumar
Published: March 2023

Epilepsy is a neurological condition that distresses millions of individuals throughout the world. The lives of epileptic patients are greatly influenced by the early detection of impending seizures. In this paper, Design an Efficient FPGA Based Hardware Implementation for Real-Time Mobile Epileptic Seizure Prediction Using Deep Neural Network. This research study uses correlation deep learning replicas through an FPGA enactment of the modified short-time Fourier transform (MSTFT) block to improve epileptic seizure detection. EEG data is pre-processed for time-frequency analysis of EEG segments using an FPGA-based MSTFT. Mounting-based Matrix Factorization (MMF) extract frequency bands and feature space. Seizure detection using proposed Correlation-based deep learning neural Network (CDNN) for classification. Each layers hybrid using hyperparameter optimized using Entropy-based Grey Wolf Optimizer (EGWO) algorithm. The experimental outcomes will demonstrate that our presented technique passes the traditional techniques.
Study on the influence of different fertilization regimes on the yield and bulb quality of garlic (Allium Sativum L.)
Authors: Zhang Yongtao , Song Jiabin , Zeng Xiaoping , Zhu Haimei , Zhou Lingdi , Li Zhen , Fan Xiaorong
Published: March 2023

Purpose: The purpose of this study was to assess the effect of microbial biofertilizer and nanofertilizer on the growth, allicin content and elemental content of garlic in China.
Method: We conducted field trial of microbial biofertilizer and germanium-containing controlled release nanofertilizer along two consecutive winter periods of 2020/2021 and 2021/2022 in a major garlic production area at Pizhou city to determine the effect of treatment in comparison to the local fertilization practice.
Result: The results revealed that the application of microbial biofertilizer and germanium-containing controlled release nanofertilizer increased the bulb yield by approximately 6-28% and 14%, respectively, compared with local fertilization practice. Meanwhile, the application of microbial biofertilizer consistently increased the allicin content of garlic in year 2021 and 2022. Furthermore, we also observed a strong positive correlation between shoot nitrate concentration at spring garlic stage and the final garlic bulb yield, implying that the accumulation of nitrate content in garlic at spring garlic stage maybe beneficial to biomass accumulation through either nutritional effect and increased chilling tolerance.
Conclusion: Taken together, our results revealed that the application of microbial biofertilizer and germanium-containing controlled release nanofertilizer can increase growth and nitrogen use efficiency of garlic in our experiment.
Identification and characterization of human skeletal stem cell-like cells derived from infrapatellar fat pad
Authors: Xu Yan , Xun Jinrui , Li Zan , Lou Wenqiang , Shi Xin , Qiu Xinzhu , Zhang Tao , Yong Cao , Li Na , Hu Jianzhong , Xu Ren , Lu Hongbin
Published: March 2023

Background
Skeletal stem cells (SSCs) have attracted extensive attention for their crucial role in bone accrual and therapeutical values. The substantial unmet cellular need of regenerative medicine and tissue engineering calls for identification of a novel source for human SSC isolation, or even skeletal stem cell-like cells (SSCLCs).
Methods
hSSCLCs were isolated through enzyme-digestion and fluorescent-activated cell sorting (FACS) from human tissues including placenta, cord blood, Wharton’s Jelly and various adipose depots. Proportion of hSSCLCs in all those tissues were compared through flow cytometry. For adipose tissue, immunofluorescent staining was also employed to substantiate our flow results. In vitro CFU-F assay, chondrogenic and osteogenic assays were performed to assess self-renewal and multipotency for differentiation of hSSCLCs. Transcriptomic profiling of adipose-derived hSSCLCs was achieved through scRNA-seq.
Results
Here, we illustrated that adipose tissues contain a satisfying abundancy of hSSCLCs, especially infrapatellar fat pad (IPFP), but not fetal tissues. Moreover, we discovered IPFP-derived hSSCLCs display intact self-renewal and a marked elevation in chondrogenic and osteogenic differentiation. Transcriptomically comparing IPFP-hSSCLCs and dorsal adipose depot (DSAT)-derived hSSCLCs through scRNA-seq, we further demonstrated IPFP-hSSCLCs are less differentiated but more motivated in expressing transcriptomes related to chondrogenic and osteogenic differentiation.
Conclusion
Our study first identified adipose tissue as an alternative but encouraging source for isolating hSSCLCs with intact SSC properties which might be promising in treating diseases related to bone and/or cartilage defects.
Checking the rationality of a kind of Theta Functions by starting with a formula of Poisson
Authors: Louiz Akram
Published: March 2023

This is a mathematical example and a logical opportunity for those who doubt the summation of Poisson or the related definitions of Riemann. By using a formula of Poisson, this article makes a mathematical proof by considering that a sum is rational. We prove by contradiction that not only one infinite series is irrational but a function of real numbers defined by infinite series. Furthermore, we conclude that this function is not continuous in any point of its curve. Finally, you will find a logical explanation based on mathematical principles that may be helpful for all students of Analysis who will find a new opportunity to demonstrate.
Prediction model for seat position identification using patient profiles, bone fracture, and dislocation characteristics in a collision and non-collision motorcycle accident in Thailand
Authors: Kluakamkao Gampon , Muengtaweepongsa Sombat , Wongyikul Pakpoom , Lokeskrawee Thanin , Jantapoon Prathompong , Keelapaeng Pongsabhak
Published: March 2023

Motorcycle accidents accounted for the most common prevalence of Road traffic collision (RTC). Therefore, identifying the rider or passenger is crucial for ensuring fairness. However, patients who suffered from RTC frequently could not provide any information due to loss of consciousness, memory loss, or death. We aim to develop two separately multivariable prediction models based on the differences in the facture pattern and demographic data between the rider and passenger in collision with another vehicle and non-collision motorcycle accident. A total of 1,816 patients had fractures from motorcycle accidents. 1,583 and 233 were riders and passengers, respectively. After a multivariable logistic regression with stepwise backward elimination, six final predictors, including Age, sex, femur fracture, wrist and hand fracture, leg including ankle fracture, and pelvis and lumbar spine fracture, were required for the final models. The prediction models had an acceptable level of discrimination (auROCs of 0.79 and 0.77 for collision and non-collision accidents, respectively) and appeared well-calibrated. Overall, the prediction model is potentially useful as an assisting tool for identifying seat positions.
Carbon tax vs. carbon market: Which one could better help China’s coal-based electricity industry achieve carbon neutrality?
Authors: Li Yin , Song Yazhi , Li Zhongfei , Liu Tiansen
Published: March 2023

This paper aims to investigate which carbon pricing mechanism, carbon tax or carbon market, could better promote the carbon neutrality of China’s coal-based electricity industry that indeed exerts significant impacts on climate change and industrial prosperity. By building a stochastic electricity price model, we reveal the price shock of both carbon tax and carbon market under different carbon pricing goals. Our key empirical results are as follows. First, both carbon tax and carbon market could significantly trigger the price volatility of coal-based electricity industry, while the shock impact of carbon market on such industry’s carbon emission is more significant than that of carbon tax. Second, by both carbon pricing mechanisms, carbon emission could be reduced up to 20%, and a key premise of achieving this goal is keeping carbon price at the level of 100 yuan/ton. Third, the volatility range of electricity price, which is policy-led, could not manifest the incentive impact of economic instruments on carbon emission reduction of coal-based electricity industry. Further, policy allows the upper limit of floating electricity price up to 15%. In general, we straighten out the linkage of carbon pricing tools and coal-based electricity costs, thereby constructing a carbon pricing mechanism for coal-based electricity industry to step into China’s carbon neutrality as soon as possible.