bluuebunny/crossref_metadata_2025 huggingface dataset:
A REVIEW ON SUSTAINABLE DEVELOPMENT BY CONSTRUCTING GREEN BUILDINGS IN INDIA
Authors: Patel Nirali , Patel Roshni , Maitrey Bharat
Published: January 2023

Since the late twentieth century, the construction industry has seen significant transformation. Because the demand for housing is expanding in tandem with population growth, it must be met with all available resources. The energy resources available to humanity, on the other hand, are limited and fast dwindling. In the long run, this will have a huge impact on the situation because the demand cannot be met with the available resources. As a result, resources will be depleted to a large level, causing serious problems. There are several alternatives for dealing with this scenario. Green building construction is a viable option that can be employed instead of traditional construction because it is more energy efficient. In general, the cost of constructing a green building is more than that of a conventional building, but the overall cost of the building, including upkeep, is lower. This research study focuses on the numerous facts and trends available for study about green construction, as well as the comparison between sustainable and conventional building.
Kewenangan Peradilan Adat di Aceh Menurut Qanun No. 10 Tahun 2008 Tentang Lembaga Adat
Authors: Anshari Nur , Aminah Aminah
Published: January 2023

Pencarian solusi apabila terjadi persengketaan, perselisihan, dan pertikaian seharusnya dapat diperoleh solusinya melalui jalur peradilan adat sebelum dibawa ke jalur hukum negara. Tetapi,  keberadaan lembaga adat di Aceh seperti terkesan  tidak berfungsi atau wewenangnya tidak maksimal berjalan. Dapat dibuktikan bahwa kasus-kasus yang masih banyak dan bertumpuk untuk diadili pada Pengadilan Negeri dan Mahkamah Syar’iyah terkait dengan sengketa-sengketa yang masuk juga dalam lingkungan wilayah peradilan adat. Kajian kali ini mengangkat permasalahan  ke dalam dua rumusan masalah yaitu: pertama, bagaimana keberadaan peradilan adat di Aceh pada legalitas hukum nasional? Kedua,bagaimana kewenangan pemangku adat di Aceh pada penyelesaian sengketa menurut Qanun No. 10 Tahun 2008 Tentang Lembaga Adat? Adapun metode penelitian pada tulisan ini adalah metode kualitatif dengan pendekatan penelitian kepustakaan (library research). Hasil penelitian menunjukkan bahwa keberadaan peradilan adat telah dikukuhkan pada implementasi Qanun Aceh No. 10 Tahun 2008 Tentang Lembaga Adat dan Qanun-qanun adat lainnya yang sebagai manifestasi UU 11/2006. Selanjutnya kewenangan pemangaku adat juga telah diuraikan dengan jelas ada 18 sengketa yang ditempuh pada jalur peradilan adat terlebih dahulu jika tidak selesai baru kemudian dilimpahkan ke peradilan umum.
First Record of Vampyrum spectrum (Chiroptera: Phyllostomidae) in Valle del Cauca, Colombia
Authors: Pinto-Orozco Karen Valeria , Ramirez-Ortiz Julieth Natalia , Rey-Gómez Daniela Fernanda
Published: January 2023

There is little information on the ecology and geographic distribution of the rare species Vampyrum spectrum due to its low abundance and the paucity of records in Colombia. In a field trip to the Reserva Natural Bosque de Yotoco, Valle del Cauca, we captured a female Vampyrum spectrum in a mist net. It constitutes the first verified record of the species in Valle del Cauca, thus updating the geographic distribution of the species in the country, filling the information gap on the species for this zone and highlighting the importance of the Yotoco Forests as an area of interest for the conservation of the biological diversity of the region.
Results of clinical developments of early triple negative breast cancer drug treatment: ASCO - 2022
Authors: Andreev Dmitry A. , Zavyalov Aleksander A.
Published: January 2023

Introduction. This article continues the series of reviews of innovative clinical developments related to drug therapy for leading cancers following the ASCO-2022 Annual Congress. This time we are seeing the results of therapy for early triple negative breast cancer (hereinafter referred to as TNR) is a consequence of the fact that TNR accounts for 15–20% of cases of all breast cancers, while it is the subtype of breast cancer (hereinafter referred to as BC), for which the choice of treatment methods
is significantly limited. In Russia, state tasks have been set within the framework of the Federal project “Fight against cancer”,
which provide for a significant reduction in mortality from neoplasms, including by improving the quality
and effectiveness of drug treatment.
Materials and methods. This scientific review is based on the results of a search in the databases of the digital educational platform MEDtalks.nl, PubMed/Medline and Google. Dictionary forms were used in the search strings: "kanker", "vroeg stadium", "triple negatief", "mammacarcinoom", "clinical trials", "ASCO-2022" and others in Dutch and English.
Results and conclusion. The results presented in this article once again substantiate the prospects for further determination of algorithms for biomarker-personalized immunotherapy (in particular, pembrolizumab) as part of the combined antitumor treatment of RMZHER–/PR–/HER2– at early stages. Radiogenomics/radioproteomics technologies are a prime example of low-cost diagnostic tools that allow promptly suggesting a personalized tumor portrait in the period before biopsy. Further improvement of clinical oncoinformatics technologies (rather large arrays of omics data have already been accumulated) will contribute to a better understanding of programs for individualized choice of differentiated therapy for cancer patients, including patients with RMZHER–/PR–/HER2–.
For citation: Andreev DA, Zavyalov AA. Results of clinical developments of early triple negative breast cancer drug treatment: ASCO-2022. City Healthсare. 2022;3(4): 122–131 doi: 10.47619/2713-2617.zm.2022.v.3i4;122–131
XIX аср охири – XX аср бошларида фарғона вилоятида пахтачиликдаги ўзгаришлар
Authors: Ҳайдаров Абдулходи
Published: January 2023

Ушбу мақолада XIX аср охири – XX аср бошларида Фарғона вилоятида пахтачиликдаги ўзгаришлар, хусусан, Туркистон генерал-губернаторлиги даврида қишлоқ хўжалигидаги ҳолат, маҳаллий маъмурият томонидан пахта етиштиришга бўлган муносабатнинг ўзгариши, Ўрта Осиёга янги Америка пахта навининг кириб келиши, пахта майдонлари учун ажратиладиган ерларнинг кенгайиб бориши жараёнининг Фарғона водийсидаги мавжуд вазиятга таъсири каби масалалар кўриб чиқилган. Шунингдек, Фарғона водийсида пахта етиштиришнинг кўпайиши билан боғлиқ бўлган иқтисодий ўзгаришлар, пахтани қайта ишлаш фирмалари ва турли жамиятларнинг пайдо бўлиши ҳамда уларнинг пахтачиликни ўз назоратига олишга уринишлари манбалар ёрдамида таҳлил қилинган.
Фотимийлар сулоласи
Authors: Зоҳидов Қобилжон
Published: January 2023

Мақолада шиаликнинг исмоилийлик фирқаси пайдо бўлиши, ал-Қоҳира шаҳрининг фотимийлар сулоласи вакиллари томонидан қурилиши, шаҳарнинг  номланиш тарихи, фотимийлар сулоласи вакиллари, уларнинг ҳукмронлигининг ҳаққонийлиги таҳлил этилган.
A Critical Study of Intensive Language Courses at the Private Universities in Bangladesh: Goals and Achievements
Authors: Palma Theodore Sourav
Published: January 2023

This study examines the goals and achievements of Intensive Language Courses (ILC) at Private Universities in Bangladesh. It focuses on how the students develop four linguistic skills— the art of critical reading, elegant writing, fluent speaking, and empathic listening; their performance in appearing for the examination and professionally dealing with the public audience. It also emphasizes how effectively the learners acquire communicative competence in English and the challenges they face in learning it. The researcher has followed the descriptive method for collecting qualitative and quantitative data. Besides, the researcher has employed questionnaires and interview methods to determine the objectives, findings, and limitations of ILC. The paper highlights the expert suggestions to learners and why they must follow the ILC to foster a strong local, regional and global network; develop professionalism in academic, corporate, and social life. Finally, based on the findings, the study intends to provide recommendations to ensure the effective implementation of ILC at Private Universities in Bangladesh.
Energía y medio ambiente en edificaciones
Authors: Alpuche Cruz María Guadalupe , Borbón Almada Ana Cecilia , Ochoa de la Torre José Manuel , Galindo Borbón Cecilia María , Lovriha Irene Marincic , Córdova Borbón Fátima Anahí , Yanes Ordiales Glenda Bethina , Quijada González Carlos Eduardo , Ibarra Torúa Gema Karina , Quintana Pacheco Jesús , Ayala Corona Armando , Villarreal Andrade María de los Ángeles , Rodríguez Muñoz Norma Alejandra , Irigoyen Campuzano José Rafael , Reynoso Cuevas Liliana , Ojeda de la Cruz Arturo , Ramírez Uribe Gerardo , Apodaca Mendoza Aldo
Published: January 2023

La optimización del recurso energético es una preocupación global que abarca problemas en cuanto a su conservación, uso y ahorro. El presente libro analiza casos de estudio de ciudades con climas extremos, pues estas necesitan estrategias de diseño para desarrollar e implementar tecnologías que permitan la construcción de espacios habitables, confortables y eficientes en el consumo de energía. Los temas de estudio relacionados con la energía y el diseño de edificios son muy diversos, por lo tanto, se han seleccionado aquellos que aborden perspectivas diferentes, pero que convergen en un mismo objetivo: ofrecer soluciones prácticas y ampliar el conocimiento respecto al uso de la energía para beneficio del medio ambiente y combate al cambio climático. Coedición con Ediciones Comunicación Científica, S.A. de C.V.
Efecto de la adición de un antioxidante sobre la actividad mitocondrial y la motilidad del espermatozoide bovino criopreservado
Authors: Mejía-Flores Itzayana , Hernández-Ignacio Javier , Chiquete-Félix Natalia , Cornejo-Cortez Miguel Ángel , Lammoglia-Villagómez Miguel Ángel
Published: January 2023

El proceso de congelación-descongelación causa estrés oxidativo, estrés osmótico, shock térmico, formación de hielo intracelular, alteraciones en la  composición  de  los  lípidos  y  de  las  proteínas de la  membrana  plasmática,  disminución  de  la  viabilidad  y  motilidad  espermática, daño a la  mitocondria, al acrosoma, a la cola y promueve la fragmentación del ADN. La  mitocondria  es  fuente  de  energía  de  la  respiración  y  también  el  sitio principal  de  la  generación  de  especies  reactivas  de  oxigeno (EROs).  Los antioxidantes deben estar presentes dentro de la mitocondria en grandes cantidades para que sean efectivos en la reducción de EROs. Sin embargo, la  membrana  interna  mitocondrial  no  es  permeable  a  la  mayoría  de  las  moléculas. Diversos estudios indican que la suplementación de antioxidantes durante el proceso de congelación del semen mejora la calidad del espermatozoide congelado-descongelado en diversos grados, pero aún existe una falta de un antioxidante eficaz reconocido. Existen pocos estudios sobre los efectos de la suplementación de un antioxidante dirigido a las mitocondrias en la criopreservación del semen, por lo que el objetivo del presente trabajo es evaluar el efecto de la adición de MitoTEMPO sobre la actividad mitocondrial y motilidad de los espermatozoides de bovino criopreservados en un diluyente comercial. La suplementación del antioxidante  en el diluyente comercial, a diferentes concentraciones mejoró la motilidad espermática en un 13% y 17% con respecto al grupo control; disminuyo en un 29% y 18% las EROs y aumento el porcentaje de producción de ATP 257% y 161% en los espermatozoides de bovino congelados-descongelados. Estos resultados apoyan la importancia del uso de antioxidantes durante la criopreservación de los espermatozoides, concluyendo que el empleo de MitoTEMPO en concentraciones relativamente bajas en el diluyente mejora la calidad del semen después de la descongelación del semen.
Diagnóstico práctico y económico de cetosis por medio de un modelo lineal utilizando la correlación de glucosa y betahidroxibutirato en sangre en vacas de doble propósito
Authors: Lammoglia-Villagómez Miguel Ángel , Rojas-Ronquillo María Rebeca , Cruz-Sánchez Praxedis , Cabrera-Núñez Amalia , Chagoya-Fuentes Jorge Luis
Published: January 2023

El estado de Veracruz tiene la mayor población de bovinos del país, dónde su principal función zootécnica es el doble propósito (DP). Las vacas de DP sufren padecimientos similares a las vacas lecheras como son el balance energético negativo (BEN), descalcificación, cetosis, metritis, entre otras. Muchas de ellas no son diagnosticadas y mucho menos tratadas. En el caso de la cetosis, la manera más sencilla de diagnosticarla es utilizando un cetómetro pero resulta difícil de conseguir y su costo es elevado. El objetivo del estudio fue utilizar las concentraciones de glucosa en sangre para predecir el grado de cetosis en vacas de DP como un método más económico y práctico. Se utilizaron 54 vacas de DP en la región norte de Veracruz. Su alimentación consistió en pasturas, pulpa de cítrico, agua y sales minerales. Todas las vacas se ordeñaron dos veces al día y tuvieron una producción media diaria de 16.6±1.01 Kg, una media de 54.6±5.0 días en leche y 3.0±0.25 de condición corporal. Se colectó una muestra de sangre y se determinaron las concentraciones de glucosa (Glucómetro, OneTouch) y del cuerpo cetónico b-hidroxibutirato (BHB, cetómetro, FreeStyle). También se registró la condición corporal (escala del 1 al 5 en donde 1=emaciada y 5=obesa). La leche se midió utilizando pesadores integrados a la línea de leche (Waikato). Se utilizó el software JASP versión 0.16.3 para hacer el análisis estadístico. Los resultados indican varias correlaciones significativas (P<0.05): Glucosa*condición corporal; número de lactancia*producción de leche y número de lactancia*condición corporal. Sin embargo, la de mayor relevancia fue la correlación glucosa*BHB (-0.56 y P<0.0001). Utilizando un modelo lineal de mínimos de cuadrados (P<0.05) se predijeron las concentraciones de BHB basados en las de glucosa; los resultados fueron: Glucosa (mg/dL) 10, 15, 25 y 35 equivalente a BHB (mmol/L) 2.02, 1.71, 1.09 y 0.46; respectivamente. En conclusión, se encontró una correlación negativa entre las concentraciones de glucosa y BHB y utilizando un modelo lineal se pudo predecir las concentraciones de BHB basado en las concentraciones de glucosa. Esto es importante ya que pudiera ser posible hacer un diagnóstico aproximado del grado de cetosis, más económico y fácil de obtener.
TECNOLOGIAS DIGITAIS NA EDUCAÇÃO
Authors: Neves Guimarães de Carvalho Rozana , Da Rosa Ventura Desirê , Da Costa Xavier Ana Beatriz , Guedes Brasil de Azevedo Bruna , Albuquerque da Silva Millena , Garcia de Mello Juliana , Sousa de Aguiar Teixeira Ayra , Nascimento de Meneses Roberta , Ferreira Pereira Ana Luiza , Lima da Silva Jorge Luiz
Published: January 2023

O presente estudo ocupa-se em discorrer sobre o surgimento e incorporação das Tecnologias Digitais na Educação, não obstante, tem como objetivo relatar acerca da sua propagação e adesão durante o contexto pandêmico, relevância na construção de significados para o processo ensino-aprendizagem e o papel do professor. A pesquisa permite o aprofundamento e amplificação na temática, assim,  utilizou-se de artigos científicos dispostos nas bases eletrônicas Scielo, Google Acadêmico e Revistas que contemplassem a temática vigente para levantamento bibliográfico. Adicionalmente, buscou-se, preferencialmente, produções desenvolvidas no período de 2018 a 2022. Dessa forma, a pesquisa tem por escopo propagar e amplificar o saber acerca das tecnologias digitais na área da educação, como um recurso facilitador e inovador para a ocorrência do processo ensino-aprendizagem, trazendo reflexões sobre a forma como os indivíduos estabelecem suas relações com estas ferramentas.
O USO DA CAFEÍNA NA TERAPIA NUTRICIONAL DE PACIENTE COM DEPRESSÃO
Authors: Salgues Gueiros dos Anjos Rute , Otaviano Pereira C. de Albuquerque Mariana
Published: January 2023

Café e chá são as bebidas mais consumidas no mundo depois da água, variando o padrão de consumo diante a cultura de cada país. Estudos demostram o uso da cafeína em pacientes adultos com depressão relacionada a sua genética e ao uso de fármacos. Esta revisão teve como objetivo avaliar o uso da cafeína na terapia nutricional de pacientes com depressão, caracterizar a influência e suas respostas metabólicas além de abordar estratégias nutricionais para melhora do quadro clínico na depressão. Tendo em vista que o número de casos da depressão cresce a cada dia, torna-se um problema na saúde pública relevante para a nutrição. Estudos abordam que a ingestão de alguns alimentos pode contribuir com a diminuição dos sintomas da depressão e proteção da função neuronal, além disso, fatores ambientais podem interferir trazendo prejuízos a saúde. Esta revisão abordou uma bibliografia que incluam artigos científicos e teses relacionados a depressão, cafeína, doenças neurológicas, citocromo p450 e metabolização fármaco-nutriente. Eles foram selecionados de acordo com critérios de inclusão e exclusão, utilizados bancos de dados com relevância científica, Pubmed, Scielo, publicados nos idiomas inglês, português e espanhol, por meio dos descritores em Ciência a Saúde (DeCS): antidepressivo, café, depressão, nootrópicos e terapia nutricional. Com essa revisão, foi verificado quais os benefícios e malefícios do consumo de alimentos que apresentam teores de cafeína, juntamente com a terapia medicamentosa de pacientes com depressão e sua influência na melhora cognitiva e neuroproteção, na prevenção de doenças neurodegenerativas e no bem-estar destes indivíduos.
Perception and Attitude of Malaysian Community Pharmacists Towards the Implementation of Telepharmacy
Authors: Ng Wei Liang , Wei Thing Sze
Published: January 2023

Introduction: Telepharmacy refers to the delivery of pharmaceutical care service through telecommunication to patients in locations where they may not have direct contact with a pharmacist. During the COVID-19 pandemic, the role of pharmacist has expanded to provide services remotely through telepharmacy. This study aimed to assess Malaysian community pharmacists’ perception and attitude towards implementing telepharmacy. Method: This cross-sectional study was carried out from August 2020 to October 2020 using an online self-administered questionnaire. 217 community pharmacists in Klang Valley were recruited through convenience sampling method. 5-point Likert scales were used to evaluate the respondent’s perceived benefits, perceived barriers and attitude towards the implementation of telepharmacy. Results: 37.8% of the respondents showed positive perception while 53.9% are moderately positive towards towards the benefits of telepharmacy. Age (p=0.019) was shown to impact on the perceived benefits on implementation of telepharmacy. Only 8.3% of the community pharmacists perceived low barriers in telepharmacy implementation and it was significantly associated with education level of the respondents (p=0.032). Younger community pharmacists and community pharmacists who have less years of working experience were more likely to have a positive attitude towards the implementation of telepharmacy (p<0.001). Conclusion: In conclusion, most Malaysian community pharmacists practicing in urban area has shown positive perception and attitude towards the benefits and implementation of telepharmacy. However, the perceived barriers towards its implementation is high. A separate training or education on telemedicine may be useful to promote the use of telemedicine to all the pharmacists.
The Psychological Impact of Covid-19 Pandemic on the General Population of Oman: A National Community-based Study
Authors: Al-Jadidi Saleha , Al-Harrasi Maryam , Mohd Kassim Norizan , Alkalbani Ali , Muthukrishnan Akila , Al-Shukaili Ahmed
Published: January 2023

Introduction: Despite evidence that that the coronavirus disease 2019 (COVID-19) in general poses unprecedented risks, it is unclear to what extent these consequences have affected the mental health of the general population. This study aims to evaluate the psychological impact of the COVID-19 pandemic on the general population in Oman and to associate the physical health status and psychological impact. Methods: A cross-sectional online anonymous survey in which 831 adults from Oman’s general population were randomly sampled as per the inclusion criteria. The medical research and ethics commission approved the project. Data were collected after obtaining informed consent from the study participants. The criteria of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders was used to measure the psychological impact. Results: Among 831 respondents in this study, only 4.2 % and 14.9 % of total participants reported depressive and anxiety symptoms, respectively. There is a statistically significant difference in psychological scores between males and females at the p < .05 level: F (1, 829) = 16.03, p < .001. As a result of this discovery, it appears that women are mentally affected by the pandemic. Conclusion: The COVID-19 epidemic has had a severe impact on the general population’s psychological health in Oman. This survey found that the global health crisis has a psychological impact on most of the adult population, regardless of their age. As a result, early detection, urgent medical intervention, and counseling are required.
Medication Appropriateness among Older Persons Admitted to a General Hospital in Malaysia
Authors: Heng Ker Sin , Tan Kit Mun , Khor Hui Min , Ahmad Tarmizi Noor Azleen , Sellappans Renukha
Published: January 2023

Introduction: Many tools have been developed to determine medication appropriateness in older persons including the 2015 American Geriatric Society (AGS) Beers criteria and the Screening Tool of Older People’s Prescriptions (STOPP) criteria. We aimed to determine and compare the prevalence of potentially inappropriate medications (PIMs) based on the Beers criteria 2015 and the STOPP criteria v2 among older persons admitted to a general hospital in Malaysia. Methods: A cross-sectional study comprising of 160 patients aged 65 years old and above admitted to the general medical wards of a tertiary teaching hospital were recruited. Beers criteria 2015 and the STOPP criteria v2 were used to evaluate participants’ medication list on admission, during hospitalisation and on discharge for PIMs. Prevalence of PIMs which was calculated as the total number of patients with one or more PIMs over the total number of patients. Results: The prevalence of PIMs identified by Beers criteria 2015 on admission, during hospitalisation and on discharge were 54.85%, 64.40% and 48.80% respectively. The prevalence of PIM based on STOPP criteria v2 were 33.08%, 47.50% and 42.50% respectively. The most prevalent PIMs according to Beers criteria 2015 and STOPP criteria v2 were diuretics, tramadol, ticlopidine, proton pump inhibitor, benzodiazepines and antipsychotics. Conclusion: The prevalence of PIMs use is high among hospitalised older persons in Malaysia. While it is not possible to avoid all PIMs listed in the Beers and STOPP criteria, clinicians should exercise caution in prescribing drugs such as benzodiazepines, antipsychotics and proton pump inhibitors for older persons weighing the risk versus benefit of the drugs.
Density Of Eggs and Larvae of Aedes Spp. and the Characteristics of their Larvae Habitat in Endemic Dengue Area In Ternate City
Authors: Tomia Sumiati , Hadi Upik Kesumawati , Soviana Susi , Retnani Elok Budi
Published: January 2023

Introduction: Dengue Fever (DF) is a disease spread by Aedes spp. caused by dengue virus infection. The study aimed to identify the density of egg and larval Aedes spp. stages and the characteristics of their habitat in dengue-endemic areas in Ternate City in September 2021. Methods: the research was conducted in four dengue-endemic villages in Ternate City, including Sangaji, Maliaro, Bastiong Karance, and Bastiong Talangame. In 80 households, egg density was determined utilizing ovitrap placement of up to two pieces per dwelling, one inside and one outside the house. After a week of ovitrap installation, the filter paper was collected, and the ovitrap index value was calculated. The value of the House Index (HI), Container Index (CI), and Breuteu Index (BI) was used to calculate the larval density. The type and materials of the containers were used to assess the parameters of the larval environment. Results: The ovitrap index value in the four sub-districts was categorized as moderate level 3 (27.50% -36.25%). The highest larval density was found in Sangaji Village (HI = 81%), while the lowest was in Bastion Talangame Village (HI = 70%). The highest CI and BI values were found in Bastiong Karance Village (CI=51.5% and BI=190%), and the lowest was in Maliaro Village (CI=37.5% and BI=128%). Density figures in all endemic villages have a high larval density with a value of 8. Conclusion: There was no significant difference (p>0.05) between the types and the materials of containers in each village in DF endemic areas. The high density of the egg and larval stage and the information characteristic of habitat Aedes spp. Could be considered the basis of information dengue vector prevention and control in Ternate City.
Tips for Managing Resistance to Innovation in Medical Education
Authors: Malik Alam Sher , Malik Rukhsana Hussain
Published: January 2023

Resistance to innovation is a natural protective mechanism and it should be perceived as a “conditional acceptance” rather than outright rejection. The change agents need to take a number of steps to convert the conditional acceptance to a “welcome change”. The aim of this article is to equip the staff members in the institutions of higher learning with tools for effectively managing the resistance to innovations in medical education. We examined the published literature in the area of managing the resistance to change and combined it with our own experiences in the established as well as new medical schools in two Asian countries and developed 12 tips to assist the change agents to manage the resistance to innovations effectively. Application of these tips will help change agents to use their time and efforts efficiently and effectively to achieve credible and lasting changes in the field of medical education.
Clinical and Haematological Parameters of Commonly Reported Non-deletional α-thalassaemia Mutations in Southeast Asia: A Review
Authors: Vijian Divashini , Wan Ab Rahman Wan Suriana , Ponnuraj Kannan Thirumulu , Zulkafli Zefarina
Published: January 2023

Alpha (α)-thalassaemia is a common genetic disorder worldwide caused by the deletion and rarely non-deletional mutations of the α-globin gene. Nearly 70 types of non-deletional mutations have been reported worldwide, and this review focuses on the common ones affecting α-thalassaemia patients. The common mutations are initiation codon mutation, codon 30, haemoglobin (Hb) Constant Spring, Hb Quang Sze, Hb Adana and Hb Evora. The haematological parameters of non-deletional mutations usually show mild changes. However, a severe reduction in haemoglobin level, mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV), and mean corpuscular haemoglobin count (MCHC) has been observed among compound heterozygous HbH disease, involving both deletional and non-deletional mutations. Although non-deletional mutations are rarely reported, it requires the study of more cases to understand the clinical phenotypes that lead to severe clinical manifestations.
Effect of Auditory Stimulation by Upbeat Music on Radial Pulse
Authors: D Almeida Prathibha Maria , Mandal Tatiyana , Bin Ahmad Norazman Saidi , Bt Zaharud Nur Shakirah , Bt Abdul Halim Nur Syazzwanis , Bt Ab. Raof Nur Athirah , Bin Nazri Nur Aldil Hakim , Kamath Shobha Ullas , S Rai Kiranmai
Published: January 2023

Introduction: Music of varying tempo or beats have physiological as well as adverse effects on the body. This study throws light on the influence of upbeat music on properties of radial pulse, in healthy young adults. Methods: One hundred and seventy-five students between the age of nineteen and twenty-four years were included in this study. The experiment was conducted in a room, devoid of any external disturbances. Subjects were made to listen the chosen upbeat music for 4 minutes using a headphone. The radial pulse was measured before and immediately after the experiment. Data analysis was done by using SPSS software version 16.0.Results: In this study we observed that normal mean pulse rate was 76 per minute in males and 72 per minute in female young adults. Following the auditory stimulation with upbeat music, rise in pulse rate was observed in more than 70% of subjects. Whilst, 24% showed a decrease pulse rate and 5% showed no change in pulse rate. Increased pulse rate was associated with decrease in amplitude of pulse wave but no change in rhythm and character of the pulse when compared to resting state. Conclusion: This study indicates that the music can increase the pulse rate in the majority of the subjects but also decreases the pulse rate in few individuals. This study provides the preliminary evidence to promote the music therapy in many preventive programs for patients with depression, patients with depressed cardiac functioning and useful in improving daily performances.
Factors Affecting Intention to Use Fully Electric Bike Transport of Ride-Hailing Applications: The Utaut Approach
Authors: Cahya Handy Nur , Sukresna I Made
Published: January 2023

Since electrify is booming around the world as one of the global warmings, many lives aspect in trying to be nice to environment by trying to go electric.  So did in Indonesia, there has been a change in public spending behaviour from conventional to electronic, even on the most basic element, i.e., transportation. The purpose of this study is to identify critical factors affecting consumers’ adoption of ride-hailing applications in specific fully electric vehicle provider by using the Unified Theory of Acceptance and Use of Technology (UTAUT) approach. This study uses convenience sampling method. Data then compiled from self-administered questionnaire, with a total usable sample are 146. The respondents are Beam Rover fully electric bike consumers. The study employs PLS-SEM technique to analyse the relationships among variables. The findings show effort expectancy, performance expectancy, social influence, and facilitating conditions positively influence behavioural intention to use Beam Rover, fully electric bike ride hailing service. The results enrich the empirical evidence of consumer behaviour in term of ride hailing in fully electric bike transport modes. At the end of this study, theoretical and practical contributions are provided.
Pelatihan Perpajakan untuk Meningkatkan Kompetensi Siswa Siswi SMK di Jakarta dan Tangerang
Authors: Febrianti Meiriska , Christina Silvy , Suparmun Haryo , Sumarta Rian
Published: January 2023

Tax is an important role for a country, because the main source of state revenue is obtained from the tax sector. To support state revenues from the taxation sector, taxpayer awareness and compliance is required, both in terms of calculation, deposit and tax reporting. Trisakti School of Management through P3M (Center for Community Research and Development) implementing the tri dharma of higher education is also responsible for being able to play a role in providing an understanding of taxation for the community through Community Service activities. The purpose of this community service activity is to provide knowledge and understanding of tax rights and obligations, namely regarding the calculation and filling of the Annual Income Tax Return for Individuals. The methods used in this training are through lectures, practice case studies and question and answer. The result achieved in this training activity is that the participants can understand how to calculate and fill out the Annual Personal Income Tax Return using forms 1770SS and 1770S. The expected targets and outcomes for participants in this training are participants can understand their tax obligations, and have the awareness to fill out Annual Tax Returns independently, completely and correctly so that taxpayer reporting compliance also increases.
Pemberdayaan Ibu Rumah Tangga Melalui Ekonomi Kreatif Agroindustri Jamur Tiram
Authors: Sumarliani Sri , Hastuti Sri
Published: January 2023

Women who become housewives make some women only rely on income from their husbands as the head of the family. Meanwhile, women also have a big role in poverty reduction activities through the empowerment of housewives to improve the welfare of their families by carrying out productive business activities.  This activity aims to empower housewives to improve the family economy through processed raw oyster mushrooms into one processed product such as chips, noodles, meatballs, oyster mushroom broth that can be consumed by the community and can be optimally developed into preparations with a high selling value. The method used is socialization and awareness that innovation in processed oyster mushrooms through the empowerment of housewives who are members of the oyster mushroom farmer group "Manut" by facilitating education and training, as well as facilitating to communicate, coordinating with the Lumajang Regency Health Office and the Lumajang Regency Trade Office collaborated to expand marketing and make oyster mushrooms into superior production. The Manut Oyster Mushroom Farmer Group turns raw materials into processed materials so that the mushrooms do not rot quickly and the processed oyster mushrooms that have been packaged become durable. In terms of economic value, processed mushrooms have basically experienced an increase in income and are also related to managing or combining to determine processed priorities in order to maintain and improve life with the creative economy.
Penulisan Abstrak Berbahasa Inggris untuk Karya Tulis Ilmiah
Authors: Sari Mike , Ningsih Pretty Elisa Ayu , Saswandi Tri , Ihsan Rodiyal
Published: January 2023

In composing a scientific paper, unique is one of the foremost critical parts. Abstacrt is portion of logical paper that contained data around the paper itself. Theoretical is composed briefly, concisely, and conclusively. Be that as it may, STKIP Muhammadiyah Sungai Penuh understudies still faound challenges in composing a unique one. This movement pointed to socialize almost methods in composing an English theoretical for the logical composing to the understudies. the strategy utilized in this movement was socialization and address by the speaker who were the PkM group. This group was comprised of 4 English Think about Program speakers of STKIP Muhammadiyah Sungai Penuh. The result of this movement appeared that the understudies were able to (1) know what theoretical is (2) know the function of theoretical within the logical composing (3) utilize the fitting tenses in writing English theoretical. The victory of this action can be seen from the assessment did by the PkM group amid this movement handle and it might moreover be seen from the assessment did by the PkM group amid this movement handle, the process of oral test, questions and answer session, and it seem too be seen from the criticism given by the understudies at the conclusion of this action.
Teknik Pengemasan dan Labeling Produk Olahan Makanan Ringan di Desa Pematang Gajah
Authors: Sophia  , Erwandri Epit , Varina Firna
Published: January 2023

Good and attractive product packaging and labeling techniques are needed to support a food product. Not all food business actors such as Micro, Small and Medium Enterprises (MSMEs) can apply modern packaging techniques. Until now, product packaging techniques are still a problem for food businesses, especially Micro, Small and Medium Enterprises. Problems regarding product packaging and labels become obstacles for the development or progress of a business. The problem that occurs in snack business actors in Pematang Gajah Village is that business actors do not know how to package products in an attractive way so that buyers can easily recognize them. The purpose of community service activities is to transfer packaging knowledge and technology so that production is easy to market. This community service activity takes the form of mentoring, counseling and training for micro-entrepreneurs processing snacks, such as sweet potato chips, banana chips, peanut brittle and fish crackers in Pematang Gajah Village, Jambi Outer City District, Muaro Jambi Regency. Product packaging functions as a means of protecting the product and increasing the attractiveness of the product in the market, while labeling functions as the identity of a product so that consumers can choose the right product.
Penulisan Artikel Ilmiah Bereputasi Bagi Guru Sekolah Dasar Kota Padang
Authors: Erpidawat  , Yuliastanty Susi , Nazif Hazlif
Published: January 2023

Requirements for teacher rank, especially in Group IVa to IVb, require special requirements, namely one journal published with ISSN both nationally and locally, in this case there are still many teachers who do not understand how to write an article taken from an existing PTK. The purpose of this service is to provide training to elementary school teachers in Padang City in writing reputable scientific articles. Until now there are still many Padang City elementary school teachers who have remained in group IVa and even for years now there are mandatory requirements that must be met for credit scores from the sub-element of scientific publications and/or elements of innovative work. The results obtained from this workshop are increasing teachers' understanding of writing reputable scientific papers and producing scientific papers from teachers.
CODAS, TOPSIS, and AHP Methods Application for Machine Selection
Authors: Dominguez Luis Asuncion Perez , Borroel Estrella Zamarripa , Quezada Oscar Eduardo Ibarra , Ortiz-Munoz Diana , Najera-Acosta Alejandro
Published: January 2023

Currently, companies have the need to make a robust analysis about the performance of their processes. In this regard, this article proposes the use of tools focused on the selection of machines, methods such as CODAS, TOPSIS, and AHP. In this study, it is sought to optimize the decision for equipment selection through multicriteria decision-making methods, maximizing the process reliability, since it is something that is demanded by the market, thus improving the quality of the finished product offered by companies. Thereby, this work addresses the comparison of these methods using real data from a case of study involving a machine selection for a pastry company, specifically it is looking for a certain kind of mixer machine that will help to improve the times of process and the quality of the final product. It shows how easy and relevant these methods are for small businesses and huge companies to motivate them to improve their selection processes explaining each method and then the application for each one comparing the results and finally doing a projection for this company’s best choice.
 
Received: 27 September 2022 | Revised: 28 December 2022 | Accepted: 2 January 2023
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
A Cognitive-Based Similarity Measure for Decision-Making with Spherical Fuzzy Information
Authors: Sharaf Iman Mohamad
Published: January 2023

The study aims to develop a new perspective of similarity measures for the recently introduced spherical fuzzy sets (SFSs). SFSs have several favorable properties making them superior to other types of fuzzy sets. As a consequence, SFSs are currently subject to extensive study to establish robust measures. Similarity measures are one of the known measures of fuzzy sets. In the spherical fuzzy environment, some of the extant similarity measures cannot satisfy the axioms of similarity and provide counter-intuitive cases. Moreover, these conventional similarity measures are generalizations of similarity measures for intuitionistic and Pythagorean fuzzy information. None of them reflects the cognitive dimension of a SFS. Hence, the concept of the cognitive impact of a SFS is introduced. The cognitive impact is the logical implications for what human perception ought to ensue. Based on this concept, a new similarity measure is introduced. While the conventional similarity measures are based on the position of the SFSs relative to each other, the novel similarity measure is based on the effect of each evaluation on decision-making. First, an extensive review of the similarity measures for SFSs is presented. Second, the new concept of cognitive impact is introduced in the spherical fuzzy environment. Then, the novel similarity measure is developed. A comparative analysis between the novel similarity measure and the extant similarity measures is conducted. Finally, a multiple criteria decision-making (MCDM) problem is solved namely, green supplier selection using the proposed cognitive-based similarity measure to check its applicability and its validity.
 
Received: 21 October 2022 | Revised: 5 December 2022 | Accepted: 23 December 2022
 
Conflicts of Interest
The author declares that he has no conflicts of interest to this work.
Endometrial stromal neoplasia: An uncommon tumor at a tertiary health centre in coastal India
Authors: Rao Ranjitha , D. Lobo Flora , K. Suresh Pooja , Sreeram Saraswathy , Murali Nirupama , K. Sahu Kausalya , Sharel Mendonca Bryne
Published: January 2023

Introduction and Aim: Stromal malignancies of uterus are rare and accounts for 1-3% of all female genital tract malignancies. They are known to pose a diagnostic challenge to the clinicians and the pathologists.  They show non-specific clinical features, gross appearance, varying histological and immunohistochemical features. This study highlights the important clinical, morphologic and immunohistochemical features of these tumors.
 
Methodology: Histopathologically diagnosed cases of endometrial stromal neoplasia over a period of 5 years from 2013 to 2017 were retrieved. The cases were analysed based on age, tumor size and histological types. Immunohistochemistry (IHC) was done whenever feasible.
 
Results: During the study period, we found 25 cases of endometrial stromal neoplasia. They were composed of four cases of endometrial stromal nodule (ESN), six cases of low grade endometrial stromal sarcoma (ESS) and three cases of ESS with smooth muscle differentiation. Twelve cases of carcinosarcomas and adenosarcomas and a single case of undifferentiated uterine sarcoma were seen. The mean age at presentation of Mixed epithelial stromal sarcoma (Carcinosarcoma) was 61 years while that of ESS and ESN was 46 and 47 years respectively. The mean size of ESN was 3.6cm (1.5-6cm), ESS was 4.5 cm (2-9.9 cm) and carcinosarcomas was 4.9 cm (2.5-16 cm).
 
Conclusion: Endometrial stromal neoplasia should be diagnosed after proper evaluation of gross morphology, histological features and immunohistochemical findings in correlation with the clinical presentation. In addition, genetic profiling is useful as an ancillary test. The spectrum of endometrial stromal neoplasia is a beginner’s ordeal if not aware of.
Effectiveness of Siddha treatment in the clinical condition of adnexal cyst - A case report
Authors: A. Lavanya , R. Vinodini , Kumar A. Rajendra
Published: January 2023

Adnexal masses are a spectrum of conditions from gynaecologic and non-gynaecologic sources which may be benign or malignant. The early detection and evaluation of an adnexal mass requires a high index of suspicion, a systematic history and physical examination. A 50 years old postmenopausal woman had complaints of severe lower abdominal pain especially in the right iliac region for the past 2 months. She had a history of large adnexal mass in right ovary which was later evaluated and diagnosed as a benign adnexal cyst. Due to age factor and family history surgical intervention was advised to the patient. In avoidance of surgery, patients preferred Siddha management and approached SRRI OPD. Treatment was started to the patient as per Siddha diagnostics. During the treatment the patient was relieved from symptoms gradually. Ultra-sonogram was done at the end of 12 weeks of treatment. The result showed bilaterally normal ovaries without any cyst. Follow up scans at the end of 3rd and 6th month revealed the same. Further research has to be done to prove the clinical efficacy of the prescribed Siddha medicines.
Uma abordagem enativista-ecológica para a interpretação de obras ficcionais
Authors: Camillo José Carlos
Published: January 2023

Seguindo a ideia de que os organismos mantêm sua coerência interagindo com o ambiente e que, ao fazê-lo, tornam-se criadores de sentido, os enativistas têm argumentado que em um ambiente social emerge o sensemaking participativo. Nesse caso, o significado emerge da interação entre os membros de uma comunidade. Influenciada pelo enativismo, surgiu a proposta de que o receptor tem uma participação mais proeminente na produção do sentido da ficção quando comparado ao produtor da obra ficcional. Assim, tem sido endossado, em algumas abordagens enativistas, que a interpretação de qualquer ficção depende, em última análise, de seu receptor. Neste artigo, essa perspectiva será chamada de supremacia do receptor e o objetivo aqui é argumentar contra essa perspectiva. Para construir tal argumentação, quatro etapas serão seguidas. Primeiramente, será apresentada a compreensão enativista da linguagem. Em segundo lugar, serão discutidos os argumentos para a perspectiva enativista chamada de supremacia do receptor. Na terceira etapa, serão apresentados dois argumentos para a rejeição da supremacia do receptor. Por fim, acoplando ao enativismo uma perspectiva da psicologia ecológica, será argumentado que o produtor da ficção estabelece restrições que limitarão as possibilidades interpretativas do receptor. Dessa forma, o processo interpretativo de uma obra ficcional é um esforço colaborativo envolvendo seu produtor e receptores, sendo que nesse esforço, o receptor não tem uma participação mais importante que o produtor.
O efeito estético e suas implicações para a compreensão da leitura literária
Authors: Santos Marcos Antônio Fernandes dos , Assis Emanoel César Pires de
Published: January 2023

A leitura literária consiste em um diálogo entre a obra e quem a lê, de maneira que existem condições necessárias e pré-estabelecidas para que tal diálogo aconteça. Assim, as teorias da recepção investigam e buscam explicar quais estruturas estão envolvidas na construção do texto e como elas funcionam ao conceber a comunicação entre as partes. Nesse sentido, o artigo objetiva refletir sobre o efeito estético e suas implicações para a compreensão da leitura literária, por meio de revisão bibliográfica em que se dialoga com os principais nomes da vertente da estética da recepção, tais como Roman Ingarden e Wolfgang Iser, bem como com teóricos da leitura literária, a saber Jean-Paul Sartre e Umberto Eco.
Torto Arado e a perspectiva de segunda pessoa
Authors: Fagundes Juliana De Orione Arraes , Pereira Valdomiro Alves
Published: January 2023

O presente artigo tem como principal determinação, a partir do enredo da obra Torto Arado, estudar a pertinência de uma perspectiva de segunda pessoa para a compreensão do mental. Partindo da referida obra, abordamos as perspectivas de primeira e de terceira pessoa, identificando, em seguida, a perspectiva de segunda pessoa, juntamente com sua relevância na explicação da comunicação que ocorre entre as personagens do romance. Estes dois primeiros passos são relevantes para que seja possível perceber as diferenças e semelhanças entre cada uma das perspectivas e para evidenciar a maneira como Torto Arado demonstra a centralidade da perspectiva de segunda pessoa. Na parte final do artigo argumenta-se que a perspectiva de segunda pessoa é a única que possibilita uma explicação para todas as formas de comunicação humana pois, entre outros fatores, ela é a base de uma linguagem complexa e articulada, assim como ela admite a possibilidade de conhecer os estados mentais de outras pessoas de forma direta, sem a necessidade de recorrer a simulações nem a interpretações dentro de nossas mentes.