bluuebunny/crossref_metadata_2025 huggingface dataset:
The Origin of H. s. denisovan and Their Dispersal Across Iran
Authors:   Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Derevianko A. P.
Published: October 2024

До начала XXI в. антропологами были выделены в конце среднего — первой половине верхнего плейстоцена два таксона: люди современного типа в Африке и неандертальцы с мустьерской индустрией в Евразии. Поэтому все палеолитические стоянки в Евразии, относящиеся к этому времени, связывали с мустье и неандертальцами. В 2010 г. в результате секвенирования мтДНК из фрагмента ногтевой фаланги пальца, обнаруженного в Денисовой пещере, удалось установить, что этот образец относится к особи, которая генетически отличалась от людей современного типа и неандертальцев. Таким образом, благодаря генетическим исследованиям был определен новый таксон H. s. denisovan — денисовец. Дальнейшие исследования показали, что эта популяция расселялась в конце среднего — первой половине верхнего плейстоцена на обширной территории Центральной и Юго-Восточной Азии. Перед исследователями встал вопрос о месте формирования денисовцев и путях их миграции на Алтай. В цикле статей, которые будут опубликованы в журнале, рассмотрены эти проблемы. Первая статья посвящена формированию на предковой основе H. heidelbergensis нового таксона денисовец и его миграции через Иран на территорию Центральной Азии.
Methodological Issues in Pollen Analysis of Pleistocene Deposits in Denisova Cave
Authors:   Lomonosov Moscow State University, Bolikhovskaya N. S. , Shunkov M. V. ,   Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences
Published: October 2024

Денисова пещера на северо-западе Алтая является наиболее информативным палеолитическим комплексом Северной Азии. Толща плейстоценовых отложений пещеры содержит находки (каменные индустрии и антропологические останки), характеризующие развитие культурных традиций денисовцев во второй половине среднего и в верхнем плейстоцене. Статья посвящена методическим вопросам палеогеографической интерпретации палинологических записей, получаемых для четвертичных отложений пещерных стоянок. Представлены материалы анализа рецентных и субрецентных спектров пещерных осадков и почвенных проб, отобранных на площадках характерных растительных сообществ природных поясов долины р. Ануй в окрестностях Денисовой пещеры. Рассматриваются результаты тафономического изучения палинологических микроостатков, выделенных из толщи рыхлых седиментаций восточной галереи пещеры. Данные исследований позволили получить корректную климатостратиграфическую и климатофитоценотическую интерпретацию спорово-пыльцевых спектров из плейстоценовых отложений Денисовой пещеры.
Slag Inclusions in Iron Artifacts from Cemeteries at Kichigino I and Krasnaya Gorka, and the Metallurgy of the Early Iron Age Itkul Culture
Authors:   South Urals Federal Research Center of Mineralogy and Geoecology, Ural Branch, Russian Academy of Sciences, Artemyev D. A. , Stepanov I. S. ,   South Urals Federal Research Center of Mineralogy and Geoecology, Ural Branch, Russian Academy of Sciences, Tairov A. D. ,   South Ural State University, Blinov I. A. ,   South Urals Federal Research Center of Mineralogy and Geoecology, Ural Branch, Russian Academy of Sciences, Naumov A. M. ,   MPI Ozersk City District “City Museum”
Published: October 2024

Приведены результаты анализа силикатных шлаковых включений в древних железных артефактах из Зауралья и железных шлаках с памятников иткульской культуры с целью установления геохимических характеристик источников железных руд в раннем железном веке. Шлаковые включения идентифицированы в 19 из 25 исследованных изделий из могильников Кичигино I и Красная Горка. Для сравнения изучены 12 железных шлаков с памятников раннего железного века — Средневековья в районе оз. Иртяш и с Зотинского рудника. На основании статистики выделены четыре геохимические группы, каждая из которых включает предметы из Кичигино I, что свидетельствует о многообразии источников железа у номадов. Шлаки и изделия первой группы ассоциируются с инфильтрационно-осадочными бурожелезняковыми рудами Среднего Зауралья. Присутствие в ней кузнечного шлака с иткульской стоянки Шатанов V свидетельствует об использовании этих руд в раннем железном веке, а наличие лишь одного артефакта из Кичигино I показывает, что номады Южного Зауралья в основном получали железо из других источников. Вторая группа выделяется повышенным содержанием во включениях Mn, иногда Ba и S. Это может указывать на бурые железняки, ассоциированные с Fe-Mn и барит-полиметаллическим оруденением Центрального Казахстана. Третья группа обособляется повышенным содержанием CaO и MgO. Для нее вероятным источником являлись бурые железняки в карбонатных платформенных толщах. Четвертая группа характеризуется высокими концентрациями K2O при низких MnO.
Textiles from the Ust-Voikary Hillfort Site (Based on Materials from 2012–2016 Excavations)
Authors:   Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Novikov A. V. , Senyurina Y. A. ,   OOO “Research Survey Ethnoarchaeological Center”
Published: October 2024

В научный оборот вводятся текстильные материалы, обнаруженные в 2012-2016 гг. в культуросодержащих слоях, датированных серединой XV — серединой XVIII в., на памятнике Усть-Войкарское городище в субарктической зоне Западной Сибири. Всего изучены 366 образцов текстиля — фрагменты одежды, некоторые из которых можно атрибутировать. Даются технологические характеристики: размер, сохранность, цвет, особенности нитей и волокон, система переплетения нитей, технологические ошибки, крой, следы ремонта. Определено, что исследуемые ткани изготовлены из сырья животного и растительного происхождения, имеют полотняную и саржевую систему переплетения нитей. Приводятся этнографические и палеозоологические данные, которые позволяют не только составить представление о текстильных технологиях у населения, проживавшего в приполярной зоне Западной Сибири, но и соотнести их с информацией об изученных ранее текстильных материалах других памятников. Сделан вывод о том, что типы тканей для пошива одежды в течение XV-XVIII вв. практически не менялись. Население использовало в основном суконные ткани, которые для данной территории являлись продуктом импортного происхождения.
The Structure of the Late Bronze Age Population of Western Siberia: Craniometric Evidence
Authors:   Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Kozintsev A. G.
Published: October 2024

Для выяснения истоков популяционной дифференциации населения Западной Сибири позднего бронзового века измерения 68 серий черепов этой и предшествующих эпох обработаны с помощью многомерной статистики. Результаты подтверждают вывод о минимум двух постафанасьевских миграциях в Сибирь с запада — доандроновской и андроновской. Представителями первой были чаахольцы, елунинцы и самусьцы. Каракольцы обнаруживают черты сходства и с ними, и с членами обеих аборигенных евразийских формаций — северной и южной, которые выглядят полюсами одного континуума. Различия между носителями двух андроновских традиций — федоровской и алакульской — вызваны скорее местным субстратом в составе первых, чем разным происхождением. Карасукская популяция, очевидно, возникла в результате метисации окуневцев с андроновцами. Носители «классического варианта» карасукской культуры ближе к первым, каменноложцы уклоняются в сторону вторых. Жители Верхнего Прииртышья и монгун-тайгинцы Байдага III близки к карасукцам. Данные по усредненной ирменской серии, сборной монгун-тайгинской и пахомовской указывают на вероятное смешение представителей обеих автохтонных формаций, андроновцев и карасукцев. Из андроноидных групп лишь еловская и пахомовская, как и серия из Еловки I, обнаруживают следы метисации аборигенов с андроновцами, а черкаскульская и корчажкинская, подобно позднекротовским из Сопки и Черноозерья и носителям бегазы-дандыбаевской культуры Барабы, уклоняются от аборигенов северной евразийской формации в сторону не андроновцев, а окуневцев. Метисация автохтонного населения с пришлым сильнее затронула южную евразийскую формацию, чем северную.
Validación de escalas de autoeficacia docente desde la perspectiva del conocimiento especializado para la enseñanza de las matemáticas
Authors: Avilés-Canché Karen , Marbán José María
Published: October 2024

El profesorado, a través de su actividad mediadora entre el alumnado y el conocimiento matemático, se convierte en una pieza clave para la consecución de una educación matemática de calidad. Sus acciones vienen condicionadas por factores afectivos y cognitivos que conviene atender desde que inicia su formación. Así, este estudio dirige su mirada hacia la autoeficacia percibida por el profesorado de primaria en formación inicial desde la perspectiva del modelo de Conocimiento Especializado del Profesor de Matemáticas (conocido como MTSK por sus siglas en inglés). Para ello, se validan dos escalas de autoeficacia docente, una centrada en el Conocimiento Matemático y la otra en el Conocimiento Didáctico del Contenido. Se detalla el procedimiento metodológico para determinar la validez y fiabilidad de ambas escalas. Los resultados muestran un ajuste adecuado de acuerdo con la estructura teórica del modelo MTSK y una alta fiabilidad, por lo que se consideran útiles como punto de partida para la medición de la percepción de la autoeficacia docente en términos de conocimiento especializado para la enseñanza de las matemáticas a lo largo de la formación inicial del profesorado de primaria.
Diseño y validación de un cuestionario de Bienestar Escolar en Educación Primaria
Authors: Losada-Puente Luisa , Mendiri Paula , Rebollo-Quintela Nuria , Fraguela-Vale Raúl
Published: October 2024

Medir el bienestar escolar permite obtener información importante sobre las percepciones de la infancia en uno de los lugares donde pasa buena parte de su día a día. El objetivo del presente estudio fue diseñar y validar un instrumento de medida del bienestar escolar en Educación Primaria (CUBE-EP). Esto se realizó en varias fases aplicándose, finalmente, a una muestra de 644 estudiantes (49.2% niños, 46.1% niñas) de 4º a 6º curso. Se llevó a cabo un análisis exploratorio (n = 328) y confirmatorio (n = 316). Se obtuvo un modelo conformado por seis dimensiones correlacionadas (actitud y comportamiento docente, relaciones entre iguales, conflictos entre iguales, metodología docente, emociones positivas y emociones negativas) en las que se integran los 29 ítems que componen el instrumento final. Se confirmó la invarianza factorial por sexo y se comprobó la fiabilidad compuesta y la varianza media extraída. Sus propiedades psicométricas lo convierten en una herramienta válida y fiable para su uso en la investigación del bienestar escolar y para que los centros educativos puedan realizar un diagnóstico con el que implementar acciones para la mejora del bienestar escolar de su alumnado.
Analysis of vertebrotomy treatment in children with congenital scoliosis with unsegmented rod and rib synostosis
Authors: Asadulaev Marat S. , Vissarionov Sergei V. , Shabunin Anton S. , Rodionova Kristina N. , Novosad Yury A. , Toriya Vakhtang G. , Kokushin Dmitry N. , Khusainov Nikita O. , Filippova Aleksandra N. , Ryzhikov Dmitry V.
Published: October 2024

BACKGROUND: Congenital anomalies of vertebral development account for 2%–11% of cases in the general structure of nosologies that cause spinal deformity. An unsegmented rod (unilateral violation of vertebral segmentation) is attributed to a prognostically unfavorable malformation. Rib synostosis causes the development of thoracic insufficiency syndrome.
AIM: To analyze the results of treatment of children with congenital scoliosis caused by an unsegmented rod and rib synostosis by vertebrotomy.
MATERIALS AND METHODS: This cohort, retrospective, monocenter study evaluated the treatment results of 55 patients. The patients were divided into two groups: group 1, children aged 2–8 years, the scope of intervention was wedge-shaped osteotomy of a non-segmented rod at the apex of the deformity, and group 2, children aged 8–18 years, the scope of intervention was wedge-shaped osteotomy at the apex of the deformity and two linear osteotomies of a non-segmented rod in the cranial and caudal directions. Clinical, radiological, and statistical research methods were used.
RESULTS: Significant correction of scoliosis was achieved in 65.5% of patients aged 2–7 years (group 1) and 56.3% in children aged 8–18 years (group 2). Hypokyphosis of the thoracic spine was observed in the patients. The percentage of correction of kyphosis was 21.1% in group 1 and 19.1% in group 2. Lung volume increased by 27.9% (p = 0.01776) in group 1, and lung volume on the concave side increased by 23.5% (p = 0.04975) and on the convex side by 29.6% (p = 0.01073). Improvement in the overall respiratory impedance reached 47.3% (p 0.05). In group 2, a insignificant increase was found in VVC by 12.6% (p = 0.3509) and FEV1 by 8.7% of the initial (p = 0.1534), as well as an increase in total lung volume of 13.3% (p = 0.1527) and the contribution of the lung along the concave side of 18.8% (p = 0.1535), and the lung along the convex side was 8.4% (p = 0.169), indicating no significant impact on lung development and function.
CONCLUSIONS: In children with spinal deformity caused by a non-segmented rod with normal respiratory function, vertebrotomy at the apex of the deformity with subsequent correction and stabilization of the spinal deformity is recommended. Performing simultaneous multilevel osteotomies of a non-segmented rod allows for significant correction of rigid spinal deformity.
Slipped capital femoral epiphysis in children engaged in sports
Authors: Barsukov Dmitrii B. , Bortulev Pavel I. , Pozdnikin Ivan Yu. , Baskaeva Tamila V.
Published: October 2024

BACKGROUND: Epiphysis displacement factors in slipped capital femoral epiphysis are defined as an external mechanical impact on the affected joint of different orientation and intensity, the nature of which may determine the type, direction, and severity of epiphysis displacement. There may be differences in the immediate causes of dislocation and in the nature of the course and timing of detection of the disease in children who were engaged in sports compared to those who were not engaged in sports. Identifying these differences may be beneficial for preventing the occurrence of epiphyseal displacement in slipped capital femoral epiphysis.
AIM: To determine the immediate causes of epiphyseal displacement and the peculiarities of the course of SCFE in children practicing sports.
MATERIALS AND METHODS: The study included 256 patients aged 11–14 years with slipped capital femoral epiphysis who were admitted at our center, from whom 68 patients were subsequently selected. The main group included 34 children who were engaged in sports and whose first symptoms of the disease appeared during training. The control group included 34 children who were not engaged in sports activities and whose first symptoms of the disease appeared for no apparent reason. Clinical, radiologic, and statistical methods of research were used.
RESULTS: In the main group, no severe forms of slipped capital femoral epiphysis such as bilateral displacement, acute displacement with chronic displacement, and early complications of the disease were noted, whereas in the control group, the number of patients with such conditions was 6 (17.6%), 4 (11.8%), and 1 (2.9%), respectively. Additionally, in 2 (5.9%) children of the main group, an extremely rare “valgus” displacement of the epiphysis was detected. Both cases occurred in gymnast girls owing to the use of a special “split” sitting technique.
CONCLUSIONS: Severe forms of slipped capital femoral epiphysis are less frequent in children who practiced sports than in those who were not engaged in sports. This is associated with earlier medical attention. “Valgus” displacement of the epiphysis is more common in children with slipped capital femoral epiphysis who practiced sports than in those who did not do sports. This may be attributed to the use of some of the most traumatic exercises in the training process.
Usefulness and accessibility of information on the treatment of children with congenital clubfoot: results of a survey of parents
Authors: Kenis Vladimir M. , Baindurashvili Alexey G. , Shpulev Pavel S. , Sapogovskiy Andrey V. , Melchenko Evgenii V. , Rustamov Gusein N. , Kasev Aleksandr N. , Rustamov Khushnud K.
Published: October 2024

BACKGROUND: Treatment of congenital clubfoot remains controversial from both specialists and parents regarding the details of its practical application, individual effectiveness, and follow-up, rehabilitation treatment, prevention, and treatment of relapses. The assessment of parental attitudes using an online survey optimizes doctor–patient interaction. Information available to parents regarding the diagnosis and treatment of children with congenital clubfoot is lacking.
AIM: This study aimed to assess the usefulness and accessibility of information for parents about the treatment of children with congenital clubfoot.
MATERIALS AND METHODS: To assess the usefulness and accessibility of information about the treatment of congenital clubfoot, a survey of the patients’ parents was conducted using an electronic fillable form proposed for anonymous completion in a thematic group dedicated to the treatment of congenital clubfoot on the social network “VKontakte”; the study included 5500 participants at the time of the survey (2 weeks), with 328 responses received.
RESULTS: Most parents noted a lack of information regarding clubfoot treatment before it actually began. The preferred source of information was Internet resources (i.e., websites of medical institutions and social networks). Achilles tenotomy and wearing braces raised the most questions, requiring additional information from both doctors and alternative sources. The possibility of errors and complications in wearing braces caused the greatest concern among parents, as well as possible relapses and the correctness of prescriptions during the rehabilitation treatment. Online parent communities and physician blogs are considered significant information sources. Most parents prefer to expand information about congenital clubfoot on the Internet, including social networks and popular resources.
CONCLUSIONS: Analysis of the results of an anonymous survey of parents of children with congenital clubfoot showed a significant demand for high-quality, accessible information regarding the diagnosis, treatment, and rehabilitation of children with congenital clubfoot. Significant interest in the information provided by social media and other Internet resources determines the need for competent representatives of the professional community to participate in this process.
Efficacy of a new customized navigation template for placement of transpedicular screws for unilateral access in children with congenital spinal deformity and thoracic malformation
Authors: Toriya Vakhtang G. , Vissarionov Sergey V.
Published: October 2024

BACKGROUND: Surgical treatment of congenital spinal deformities combined with thoracic development anomalies in children is an urgent and a complex problem in surgical practice. The surgical method of correcting congenital deformities caused by segmentation disorder of the lateral surfaces of vertebral bodies and unilateral rib synostosis is aimed at correcting the existing deformity using a transpedicular system. This technique is effective for treating this group of patients. However, it requires precise and accurate installation of the supporting elements of the metal structure owing to the high risk of damage to the neurovascular structures in the area of surgical intervention. A solution to this problem is the use of an individualized guide template with rib support for unilateral access in children with congenital deformities of the thorax and spine.
AIM: To perform a comparative analysis of the results of using an individual rib-supported guide template for transpedicular screw placement and the “free hand” method in children during surgical correction of congenital spinal deformities accompanied by thoracic development anomalies.
MATERIALS AND METHODS: The study included 14 patients who underwent surgical treatment for congenital deformity of the thoracic spine against the background of segmentation disorder of the lateral surfaces of the vertebral bodies in combination with thoracic anomalies. The patients were divided into two groups. Group 1 included six patients operated on using a new navigation template guide, and group 2 consisted of eight patients who underwent installation of support elements using the “free hand” method. The following parameters were compared: time spent at the stage of formation of bone canals for the support elements of the metal structure and accuracy and correctness of support element installation. Clinical data included demographic information and the size of the scoliotic arch, number of support elements, and presence of complications. Statistical analysis using Student’s t-test for unpaired samples or Mann–Whitney test was used to compare results.
RESULTS: Data obtained in the course of the study confirmed the high efficiency and accuracy and showed that the use of the template reduces the time of bone canal formation, increases the accuracy, and provides greater correctness of the position of the supporting elements compared to the “free hand” method, which increases the efficiency and safety of surgical treatment.
CONCLUSIONS: The developed template guide with support on the rib for the installation of the supporting elements of the metal structure in the surgical treatment of children with congenital deformity of the thoracic spine in combination with thoracic development anomaly showed better results compared to the use of the “free hand” method.
Experimental burn models for evaluating wound healing agents and its current situation and existing disadvantages: a literature review
Authors: Novosad Yury A. , Makarov Aleksandr Yu. , Rodionova Kristina N. , Shabunin Anton S. , Vissarionov Sergei V.
Published: October 2024

BACKGROUND: Burns remain a crucial part of the structure of injuries in Russia and abroad. Therefore, providing high-quality medical care to burn victims is relevant. Despite the large number of proposed solutions to this condition, developments in the field of tissue engineering and medical materials science still lack standardization and consideration of specific features of animal burn models for their testing. Many studies showed minor and major disadvantages from a technical and descriptive point of view.
AIM: To analyze and identify the main disadvantages of existing burn models to assess the effect of wound healing agents.
MATERIALS AND METHODS: This article examines the search results in the databases Google Scholar and PubMed using the keywords “burns,” “rats,” “animal model,” and “wound healing.” Sixty publications were analyzed.
RESULTS: Seven quality criteria for the animal burn model have been determined, which allow obtaining reliable results and reproducing the described experiment: indication of the terms of quarantine and conditions of keeping laboratory animals, detailed description of the technique of applying burn injury, presence of one burn on a laboratory animal, presence of a control biopsy, indication of the absolute value of the initial burn area, presence of surgical treatment of burn wounds, and correct use of formulas for the planimetric assessment of wound healing.
CONCLUSIONS: A solution to the problem of creating a standardized model may be a more detailed description of techniques and following the proposed quality criteria.
Onset of Aftershocks: Constraints on the Rate-and-State Model
Authors: Hainzl Sebastian , Page Morgan T. , van der Elst Nicholas J.
Published: October 2024

Aftershock rates typically decay with time t after the mainshock according to the Omori–Utsu law, R(t)=K(c+t)−p, with parameters K, c, and p. The rate-and-state (RS) model, which is currently the most popular physics-based seismicity model, also predicts an Omori–Utsu decay with p = 1 and a c-value that depends on the size of the coseismic stress change. Because the mainshock-induced stresses strongly vary in space, the c-value should vary accordingly. Short-time aftershock incompleteness (STAI) in earthquake catalogs has prevented a detailed test of this prediction so far, but the newly developed a-positive method for reconstructing the true earthquake rate now allows its testing. Using previously published slip models, we calculate the coseismic stress changes for the six largest mainshocks in Southern California in recent decades and estimate the maximum shear as a scalar proxy of the coseismic stress tensor. Aftershock rates reconstructed for events in different stress ranges show that the rates follow a power law with p = 1 independent of stress with no clear sign of a c-value. The onset of the power-law decay is abrupt and more delayed in areas with smaller stress changes. The observations do not necessarily contradict the RS model, as STAI limits the resolution for early aftershocks, and the RS model can reproduce the observations for specific Aσ values. However, the observations lead to strong constraints, namely Aσ<10  kPa and a power-law decay of the background rate with distance to the fault, with exponent 2.7.
Finlandiya’da Kamu Diplomasisi: Propagandadan Ulus Markalaşmasına
Authors: Şeyşane Volkan
Published: October 2024

Uluslararası ilişkilerde “küçük ülke” olarak sınıflandırılan Finlandiya, eğitim, yönetişim, cinsiyet eşitliği ve yaşam kalitesi konularındaki başarılarıyla uluslararası politikada iyi bir itibara sahiptir. Bu olumlu uluslararası imaj, Finlandiya hükümetlerinin 1945 sonrası dönemde yürüttüğü aktif ve bilinçli uluslararası iletişim politikalarının bir ürünüdür. Bu makale, İkinci Dünya Savaşı sonrasındaki dönemde Finlandiya’nın kamu diplomasisi uygulamalarını incelemektedir. Makale, kamu diplomasisi ve ulus markalaşması faaliyetleriyle ilgili Finlandiya’daki politika yapım süreçlerini tarihsel ve politik bağlam içinde analiz etmeyi amaçlamaktadır. Bu hedef doğrultusunda, Finlandiya’nın kamu diplomasisi etkinliklerini değerlendirmek için “bilgi temelli kamu diplomasisi” ve “ilişkisel kamu diplomasisi” sınıflandırmasına başvurmaktadır. Uluslararası siyasi ortamın Finlandiya’nın uluslararası iletişim yönetimi üzerindeki etkisini vurgulayan makale, Soğuk Savaş döneminde Finlandiya’nın kamu diplomasisi faaliyetlerinin, tek yönlü mesaj iletimine vurgu yapılması nedeniyle bilgi temelli kamu diplomasisi perspektifini yansıttığını savunmaktadır. Makale ayrıca 2000’li yıllardaki girişimlerde, ilişkisel kamu diplomasisinin etkisinin sınırlı kaldığı ve kamu diplomasisinin ulus markalaşmasına indirgenmesi nedeniyle bilgi temelli yaklaşımın etkisinin güçlü şekilde devam ettiği sonucuna varmıştır.
İsveç’in Kamu Diplomasisi 2.0 Dönemi
Authors: Erbaş Doğan Göknil
Published: October 2024

İsveç, eski ve yeni kamu diplomasisi yöntemlerini uluslararası ilişkilerinde etkin bir şekilde kullanan ülkeler arasındadır. Dünyada tanınırlık, ülke imajı, markası ve prestiji açısından İsveç’in farklı bir konumda olduğu görülmektedir. İsveç’in kamu diplomasisi alanında yarattığı fark, hem kamu diplomasisi uygulamalarındaki çok yönlü araç/yöntem kullanımı hem de İsveç kamu sektöründe kamu diplomasisi ile ilgili kurumsal yapının sağlamlığından kaynaklanmaktadır. Bu makale, yukarıda bahsedilen bu iki özelliği öne çıkarılacak şekilde İsveç kamu diplomasisinin yeni dönem stratejisine odaklanmaktadır. Makale İsveç’in kamu diplomasisi politikalarını anlatmayı değil, 2.0 stratejinin nasıl uygulandığını göstermeye yoğunlaşmıştır. Bu kapsamda İsveç’in son dönem kamu diplomasisi stratejisi olarak ilan ettiği “Strateji 2.0” dönemi uygulamalarına değerlendirilecektir.
İndirimli Lüks Moda Ürünlerinde Tüketiciler Neyi Hedefliyor? Başarı Hedefi Teorisi Perspektifinden Bir Profil Araştırması
Authors: Kılıçer Tuğba
Published: October 2024

Bu araştırmanın amacı indirimli lüks moda ürünlerini satın alan tüketicilerin profillerini ortaya çıkarmaktır. Araştırmada başarı hedefi teorisine dayalı olarak tüketicilerin lüks moda ürünlerini indirimli satın alma hedefleri incelenmiştir. Çalışma nicel araştırma metodolojisine göre tasarlanmıştır. Araştırmada yargısal örneklem tekniğinden yararlanarak indirimli lüks moda ürünlerini satın alan 184 tüketiciye ulaşılmıştır. Veriler anket tekniğinden yararlanılarak toplanmıştır. Verilerin analizinde doğrulayıcı faktör analizinden, kümeleme analizinden, tek yönlü varyans analizinden ve betimsel analizlerden yararlanılmıştır. Faktör analizi sonuçları lüks moda ürünlerinde tüketicilerin indirim yakalama hedeflerinin; uzmanlaşma, gurur yaşama ve sosyal onay boyutlarından oluştuğunu doğrulamaktadır. Kümeleme analizi sonuçları bu hedeflere göre katılımcıların üç kümede toplandığını göstermektedir. Sportif tüketiciler, rekabet odaklılar ve mesafeliler olarak adlandırılan kümelerin uzmanlaşma, gurur yaşama ve sosyal onay düzeyleri anlamlı olarak farklılaşmaktadır. Her üç küme arasında lüks moda ürünlerindeki indirim karşısında duyulan memnuniyet ve markayı tekrar satın alma değişkenleri açısından da anlamlı farklılıklar bulunmaktadır.
Predictors of pneumonia in stroke patients with dysphagia: A Turkish study
Authors: Kaşikçi Halim Ömer , Erçin Üçgül Elif , Karaci Rahşan , Ülker Mustafa , Mayda Domaç Füsun
Published: October 2024

Background and purpose – Dysphagia, characterized by difficulty in swallowing due to neurological deficits, stands out as the foremost contributor to stroke associated pneumonia (SAP) development. Recent investigations have explored the utility of blood tests, including parameters like neutrophil count, leukocyte count, neutrophil-tolymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and the CRP to albumin ratio (CAR), at the time of admission as potential markers for predicting SAP development. This study is set out to assess predictors of SAP in patients with acute ischemic stroke and dysphagia. Methods – This retrospective cross-sectional study, conducted at the University of Health Sciences, Neurology Department of Erenkoy Mental Health Neurological Disorders in Istanbul, Turkey, between January 2021 and January 2023, assessed 65 individuals with acute ischemic stroke and dysphagia. Excluding specific criteria, clinical and laboratory data were collected. Patients were categorized into SAP and non-SAP groups based on diagnostic criteria. Results provide insights into risk factors of SAP. Results – In this study of 65 stroke patients with dysphagia, 27 (41.5%) developed SAP within the first week. No significant differences in age, gender, comorbidities, or infarct size were observed between the pneumoniapositive and pneumonia-negative groups (p > 0.05). HbA1c levels were significantly lower in the pneumonia-positive group (p = 0.02). Logistic regression revealed that NLR, CAR levels, and the presence of atrial fibrillation (AF) were significant predictors of pneumonia development (p < 0.001). Conclusion – Dysphagia is considered one of the most significant risk factors for SAP. However not all ischemic stroke patients with dysphagia develop SAP; that is the reason we think NLR, CAR, and AF might be predictors of SAP in acute ischemic stroke patients with dysphagia.
L-asparaginase Conjugates of Rhodospirillum Rubrum with Polymers of Different Structures with Improved Biocatalytic Properties
Authors: Dobryakova N.V. , Zhdanov D.D. , Kudryashova E.V.
Published: October 2024

L-asparaginase from the mesophyllic bacterium Rhodospirillum rubrum shows promise as a potential biomedicine treatment for tumor diseases. To enhance the enzyme's catalytic parameters, we have synthesized covalent conjugates with chitosan-PEG, chitosan-glycol and polyethylenimine. Interestingly, binding to these polymers had minimal impact on the enzyme's substrate binding constant. The RrA-PEI conjugate showed the most significant changes in secondary structure content. The success of the previous modification was evaluated by IR spectroscopy, which indicated that the polycations used in the work have a positive effect on the catalytic activity of the enzyme. The RrA-chitosan-PEG conjugate demonstrated the highest enzymatic activity.
Recombinant Proteins Combining the Inter-domain Region of Pneumococcal Surface Antigen "A" and Adaptive W-type Polypeptide of Thermotoga Bacteria as a Potential Component Base for the Development of New Diagnostics and Genetically Engineered Subunit Vaccines against Pneumococcal Infection
Authors: Parfenova O.K. , Sidorov N.G. , Kasap E.Y. , Kurkin R.V. , Grishin D.V.
Published: October 2024

The problems related to the development of pneumococcal vaccines require combination of traditional solutions and alternative systems optimizing this procedure. Recombinant subunit vaccines have undeniable advantages over inactivated and live-attenuated vaccines: they induce cell-mediated and humoral immunologic responses effectively and with high specificity, but without the risks associated with authentic pathogen processing. However, subunit vaccines require specific adjuvants to enhance the immune response or special fusion partners to improve solubility, expression and optimize subsequent fine purification of the protein of interest. In the framework of this work, a structurally conserved region of the most immunogenic region of the vaccine-valuable surface antigen PspA of Streptococcus pneumoniae was chosen as a model protein, and the adaptive polypeptide CheW from the hyperthermophilic microorganism Thermotoga petrophila was used as a promising fusion protein. Appropriate expression plasmid vectors were designed in silico and constructed in vitro. Efficient E. coli producer strains were obtained and appropriate conditions for heterologous production of chimeric proteins were selected. The fusion partner from T. petrophila positively influenced the properties of the resulting constructs such as thermostability, solubility, and homogeneity. During this work, the optimal pH and temperature ranges of the created proteins were determined, and the principles of low-stage purification were elaborated. We obtained and characterized new proteins, which were not previously found in nature in a similar bioconfiguration. The results indicate that the biotechnologically valuable characteristics of the fusion protein were more expressed when the adaptive CheW protein was combined with the N-terminus of the PspA antigen.
New Nitrogen-containing Androstane Derivatives Suppressing Prostate Carcinoma Cells Proliferation
Authors: Latysheva A.S. , Misharin A.Yu. , Veselovsky A.V. , Morozevich G.E. , Novikov R.A. , Zolottsev V.A.
Published: October 2024

Derivatives of 3β-hydroxyandrost-5,16-diene and 3β-hydroxyandrost-5-ene containing 2-oxazoline, 2-benzoxazole, and 2-benzimidazole substituents at C-17 position were synthesized. Docking of the synthesized compounds into the active site of human CYP17A1 predicted their high affinity for the enzyme. Of the 6 new compounds, 5 suppressed the proliferation of prostate carcinoma cells LNCaP and PC-3, and the activity of the oxazoline and benzimidazole derivatives of androsta-5,16-diene significantly exceeded the activity of the known anticancer agents abiraterone and galeterone.
Estigmatización y cuidado de las enfermedades neurocognitivas y de la salud mental de la persona mayor
Authors: Camargo-Rojas Claudia Marcela , Blanco-Parraga Maria Camila , Bonilla-García Lorena Catalina , Cardona-Ocampo Maria Alejandra , Ibarra-Pacheco Tabata Sayleth , Mahecha-Forero Luna Natasha , Rodriguez-Rodriguez Liliana Marcela , Rodriguez-Peña Aniul Slendy , Sáenz-Arias Paula-Andrea , Tique-Alvarez Maria-Camila
Published: October 2024

El envejecimiento poblacional nacional y mundial ha despertado el interés por evidenciar los eventos relacionados con el proceso de salud y enfermedad de la persona mayor que son prevalentes en este grupo poblacional. De acuerdo a la Organización Mundial de la Salud, el 20 % de las personas mayores presentan alguna enfermedad mental, derivada de los procesos físicos, psicológicos y sociales del envejecimiento, así como de las enfermedades neurocognitivas.
Una situación derivada es la estigmatización de las personas mayores con enfermedad mental o con enfermedad neurocognitiva (Alzheimer-Parkinson). De acuerdo a diferentes autores se encuentra que por lo menos el 40 % de las personas con demencias consideran que son excluidas de la sociedad; también sus cuidadores y familiares se preocupan por situaciones de rechazo social.
Con el fin identificar la literatura científica relacionada con la estigmatización y el cuidado de las enfermedades neurocognitivas y de la salud mental de la persona mayor se propuso realizar la siguiente revisión de tema.
Estrategias de afrontamiento y resiliencia en profesionales en enfermería durante la pandemia por COVID-19
Authors: Quiñonez Mora Marcia Andrea , Ortiz Mayorga Judith Liliana , Henao Castaño Ángela María , Riveros-Gómez Laura
Published: October 2024

Introducción: durante la pandemia por COVID-19, los profesionales en enfermería a cargo del cuidado directo e indirecto de estos pacientes se vieron expuestos a situaciones personales, familiares y laborales altamente estresantes. Objetivo: determinar la relación entre el nivel de resiliencia y las estrategias de afrontamiento de los enfermeros que brindan cuidado directo e indirecto a pacientes con diagnóstico confirmado o sospechoso de COVID-19 en una institución de cuarto nivel de la ciudad de Bogotá. Métodos: estudio descriptivo transversal cuantitativo; la muestra estuvo compuesta por 50 profesionales en enfermería que se encontraban en los servicios de cuidado crítico, urgencias y hospitalización. Los instrumentos de recolección de datos empleados fueron la Escala de Resiliencia de Connor-Davidson y el formulario del Inventario de Estrategias de Afrontamiento. Resultados: respecto a la alta resiliencia, este estudio mostró una relación estadísticamente significativa con la formación posgradual (p = 0,017), una relación negativa estadísticamente significativa (p = 0,027) con la estrategia de autocrítica y una relación positiva (p = 0,07) con la estrategia de resolución de problemas. Conclusiones: Existe relación entre el uso de estrategias cognitivas y conductuales encaminadas a eliminar el estrés, modificando la situación que lo produce y el nivel de resiliencia en los participantes de este estudio.
Multi-Section Open Course Design: Design and Implications for Faculty, Sessional Instructors, and Learners
Authors: Irvine Valerie , Paskevicius Michael , Madland Colin , McCue Rich , Roberts Verena
Published: October 2024

As open course designs are being implemented in regular post-secondary credit courses (beyond massive open online courses), new issues and processes need to be considered that are fundamentally different from courses offered within the traditional learning management system. In this paper, we will review our approach to multi-section open course design and share our experiences working through emergent issues, such as content placement, intellectual property, attribution, etc. We will provide insights and recommendations for institutional leadership and administration, faculty area advisors, technical support staff, and sessional instructors.
Стан та перспективи використання авіаційного біопалива
Authors: Іванцов Михайло , Бейдер Елінор Єня , Барановський Михайло
Published: October 2024

Розглянуто поточний стан та перспективи використання авіаційного біопалива
Стан переробки відходів упаковки в країнах-членах ЄС
Authors: Острянська Юлія , Кузнєцова Олена
Published: October 2024

Розглянуто поточний стан переробки відходів упаковки в країнах-членах ЄС
Детоксикацiї важких металiв мiкробним препаратом з отриманням метану
Authors: Біда Ірина , Гаврилюк Олеся , Говоруха Віра , Таширєв Олександр , Ястремська Лариса
Published: October 2024

Метою дослiдження було теоретично обґрунтувати та експериментально пiдтвердити шляхи осадження розчинних токсичних металiв Co2+, Ni2+ i CrO2−4 за використання мiкробного препарату на основi неадаптованих анаеробних мiкроорганiзмiв бiогумусу та осаду бiогазової установки.
Аналiз вiдповiдностей класифiкацiї вiдходiв згiдно законодавства України та директив ЄС
Authors: Брик Анастасія , Корнiєнко Iрина , Ястремська Лариса , Кузнєцова Олена , Барановський Михайло , Монченко Олена , Черненко Яна
Published: October 2024

Проведено аналiз вiдповiдностей класифiкацiї вiдходiв згiдно законодавства України та директив ЄС
Сучасна класифiкацiя вiдходiв
Authors: Дубовчук Вадим , Ястремська Лариса , Гаркава Катерина , Косоголова Людмила , Монченко Олена
Published: October 2024

Представлено аналіз сучасної класифiкацiї вiдходiв
Сучасні підходи країн ЄС до циркулярної економіки
Authors: Кузьмінська Анастасія , Корнiєнко Iрина , Ястремська Лариса , Кузнєцова Олена , Барановський Михайло
Published: October 2024

Розглянуто сучасні підходи країн ЄС до циркулярної економіки
Бізнес-моделі циркулярної економіки, спрямовані на переробку картопляних відходів
Authors: Лисенко Едуард , Ястремська Лариса , Корнiєнко Iрина , Кузнєцова Олена , Барановський Михайло
Published: October 2024

Розглянуто бізнес-моделі циркулярної економіки, спрямовані на переробку картопляних відходів
Еколого-економічна оцінка технологій переробки сільськогосподарської продукції
Authors: Мойсієнко Марія , Кузнєцова Олена , Гаркава Катерина , Барановський Михайло , Косоголова Людмила , Монченко Олена
Published: October 2024

Проведено еколого-економічну оцінку технологій переробки сільськогосподарської продукції.
Стратегія впровадження альтернативної енергетики для розвитку циркуляційної економіки України
Authors: Степанюк Олена , Гуляєв Віталій , Коваленко Алла , Анацький Андрій , Фiлiмоненко Ольга , Чубко Лариса , Кузь Тетяна
Published: October 2024

Розглянута стратегія впровадження альтернативної енергетики для розвитку циркуляційної економіки України
MEGHÍVÓ A KORAGYERMEKKORI NEVELÉS CÍMŰ NEMZETKÖZI TUDOMÁNYOS KONFERENCIÁRA
Authors: . .
Published: October 2024

Date: 2016. May 25-26.Place: Debreceni Egyetem Gyermeknevelési és Felnőttképzési Kar (Hajdúböszörmény, Désány István u. 1-9.)
GYÓGYPEDAGÓGUS KÉPZÉS INDUL 2017-BEN A DEBRECENI EGYETEMEN
Authors: . .
Published: October 2024

SPECIAL EDUCATION TEACHER TRAINING STARTS AT THE UNIVERSITY OF DEBRECEN IN 201
A FOTOTERÁPIÁS ESZKÖZÖK KREATÍV ALKALMAZÁSA AZ OKTATÁSBAN
Authors: Csermelyné Gáspár Tímea
Published: October 2024

The Educational Service functions in interdisciplinary teams. The services are primarily used by children with special educational needs, along with their parents and educators. The best practice was made by thinking in an integrated service model, based on solution-focused, children – and family-oriented experiences. One of the cornerstones is coaching, especially those tools, that inspire phototherapeutic self-knowledge and the solutions of problems, Points of You™ (Efrat Shani & Yaron Golan, 2007). The phototherapeutic picture – and word cards function as projective surfaces. They stimulate both of the cerebral hemispheres at the same time, causing an intentional confusion between the logical left hemisphere and the intuitive right one. That’s when the person is able to see a new point of view and have an „aha experience”. The new point of view can already lead to the recognition of new possibilities. The Educational Service of Hajdú-Bihar County introduced the phototherapeutic method to its educational practices in a lot of areas of the service, innovatively and uniquely in the country, on an organizational level. In the area of educational and psychological counseling and development, this method can be used in individual, couple, and group forms, as well. People can use it to develop themselves, it can be used with children, parents, educators, and other processes. The core institution of the Ministry of Education has been making this best practice popular for years now.
JÁTÉKTERÁPIA SÉRÜLT CSECSEMŐKNEK ÉS KISGYERMEKEKNEK A KORAI FEJLESZTÉS ÉS GONDOZÁS TERÜLETÉN
Authors: Erdős Mónika
Published: October 2024

The experts of early development working in the Hajdú-Bihar County Educational Service worked out new therapy for the damaged babies, young children, and their families while taking the local factors and resources into consideration. This therapy strongly fits the family-oriented approach and the coordinated, integrated provider model of early childhood intervention. The tool for this is play therapy, which is the most important element of the development of damaged children. The program is based on the healing play therapy designed by Tunyogi (2019). We added some elements of the Step By Step preschool program to the therapy, and for the design of the environment and conditions, we used the Work-Fun-Development concept of Schaffer (1988) Parts of the intensive, group play therapy: sensorimotor program, the differentiated stimulation therapy of the senses, the increase of learning abilities, a staged environment. This year, new elements and therapeutic tools have been added to the program, like the Points of YouTM phototherapy method for parents, as well as dog therapy and baby massage for the little ones.
INVITATION TO THE VIRTUAL EXHIBITIONS OF THE PROJECT „T.É.M.A.”
Authors: Cube Circle Talent Development Cultural Association
Published: October 2024

The ’T.É.M.A.: Tudományos És Művészeti Alkotóműhely’ ("T.É.M.A.”: Scientific and Artistic Workshop) is a talent development program of the Hungarian "Kocka Kör Tehetséggondozó Kulturális Egyesület" (Cube Circle Talent Development Cultural Association) for secondary school students. Supporters of this project are the Hungarian National Talent Program and the Hungarian Prime Minister's Office (project ID is NTP-INNOV-22-0095). The study is an invitation to the virtual exhibitions of the project "T.É.M.A."
Chukhonastovka – the reference section of the Turonian-Lower Santonian from the Volga-Ilovlya interfluve (the Volga right bank area near Volgograd). Paper 2. Characteristics of the Oryctocomplexes
Authors:   Saratov State University, Pervushov Evgeny M. , Ryabov Ilya P. ,   Saratov State University, Kalyakin Evgeny A. ,   Saratov State University, PSJC “Podzemburgaz”, Shelepov Dmitry A. ,   Saratov State University, Ilyinsky Egor I. ,   LLC “SPETSPROMSERVICE”
Published: October 2024

A representative complex of the Turonian-Santonian carbonate-producing invertebrates has been revealed. It comprised benthic foraminifers, diverse echinoderms, brachiopods, calcareous and siliceous sponges.
Locally Advanced Childhood Nasopharyngeal Cancer: A Case Series
Authors: Oentario Julius , Ramli Irwan , Nuryadi Endang
Published: October 2024

Nasopharyngeal carcinoma is a rare malignant tumor in childhood. To date, no consensus has been achieved concerning the recommendations for the management of childhood Nasopharyngeal carcinoma. Chemotherapy and radiotherapy are the main modalities in the management of nasopharyngeal carcinoma (NPC). Five cases (with an age range between 10 and 16 years), including one patient with stage III NPC and four patients with stage IV NPC, are reported in this study. All patients received four courses of induction chemotherapy followed by concurrent chemoradiation with cumulative irradiation, with a dose of 70 Gy in 33-37 fractions. Patients were treated with intensity modulated radiation therapy with simultaneous integrated boost technique using helical Tomotherapy. After two-year’s follow-up, four patients were achieved complete response, one patient showed residual disease in lymph nodes in the neck and bone metastases one year after the completion of treatment. Treatment side effects were well tolerated, there was no acute toxicity grade 3 or 4, and late toxicity consisted of chronic sinusitis, grade 1 xerostomia, and grade 1 skin fibrosis.