bluuebunny/crossref_metadata_2025 huggingface dataset:
Antibiotic-Loaded Collagen Sponges in Clinical Treatment of Chronic Osteomyelitis
Authors: van Vugt T.A.G. , Walraven J.M.B. , Geurts J.A.P. , Arts J.J.C.
Published: January 2019

Background:

Chronic osteomyelitis is caused by bacterial infection of the bone and is a major problem in orthopaedic surgery. Treatment of chronic osteomyelitis requires surgical debridement accompanied by local and systemic administration of antibiotics. A widely established biodegradable local antibiotic carrier is antibiotic-loaded collagen sponges (fleeces). These sponges are commonly used in the treatment of chronic osteomyelitis, but a systematic review of their clinical efficacy and assessment of the quality of evidence have not been conducted, to our knowledge.

Methods:

This systematic review, performed according to the PRISMA statement, examined the clinical efficacy of and quality of evidence regarding different antibiotic-loaded collagen sponges in the clinical treatment of chronic osteomyelitis. Clinical efficacy was defined as eradication of infection with bone and wound-healing. In addition, the in vivo pharmacokinetics of the various collagen sponges were evaluated. Quality was based on the Level of Evidence, methodological quality, and risks of bias.

Results:

A total of 813 articles were screened, and 10 were included. Gentamicin-sulfate sponges and gentamicin-sulfate/gentamicin-crobefate sponges were studied. A total of 413 patients were treated, with a success rate of 91%. Reported complications were fistulas, prolonged wound drainage, and wound-healing problems. In vivo pharmacokinetic profiles showed an average local antibiotic concentration that was above the minimum inhibitory concentration for only 5 days. The general quality of the included studies was low to moderate, and there was a moderate to high risk of bias.

Conclusions:

The evidence quality and Level of Evidence of the included studies were low, and the risk of bias in these studies was high. This makes the evidence regarding these sponges inconclusive, and no clinical decision-making can be based on these studies. Utilization of antibiotic-loaded collagen sponges in the treatment of chronic osteomyelitis should only be carried out with caution; studies with high-level evidence are needed.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
The Sensitivity of Orthopaedic Surgeons to the Secondary Prevention of Fragility Fractures
Authors: Mo Jian , Huang Kangmao , Wang Xumeng , Sheng Xinyu , Wang Qiang , Fang Xiangqian , Fan Shunwu
Published: January 2019

Background:

Orthopaedic surgeons must play an important role in the secondary prevention of fragility fractures; however, some surgeons are more aware than others of their responsibility regarding fracture prevention. The purpose of the present study was to identify which factors can lead to a higher sensitivity for fracture prevention.

Methods:

A cross-sectional survey was distributed to orthopaedic surgeons via online invitation or at academic conferences in China from July through October 2015. A total of 452 surgeons responded. As the primary outcome measure, we created a sensitivity scoring system for fracture prevention based on the respondents’ answers to 5 questions regarding behavior in the following areas: risk-factor evaluation, pharmacologic therapy, nonpharmacologic therapy, patient education, and follow-up. Multivariable linear regression and multivariable logistic regression analyses were used to identify factors related to surgeon sensitivity to fracture prevention.

Results:

Very few surgeons reported having received adequate training regarding fracture prevention or reading guidelines or other fracture prevention literature (22% and 30%, respectively). Most respondents initiated pharmacologic or nonpharmacologic therapy (82% and 75%, respectively) for the treatment of confirmed osteoporosis among patients with fragility fractures, but only half performed a risk-factor evaluation, patient education, or timely patient follow-up (51%, 52%, and 48%, respectively). In the multivariable linear regression model, the orthopaedic surgeon’s age (β = 0.09, p = 0.003), self-rated knowledge level regarding osteoporosis or related issues (β = 0.16, p < 0.001), self-perceived effectiveness in using preventive measures for patients with a fragility fracture (β = 0.62, p < 0.001), and use of clinical pathways for fragility fractures in his or her workplace (β = 1.24, p < 0.001) were independently associated with sensitivity scores for fracture prevention. Similar results were obtained from a multivariable logistic regression model.

Conclusions:

In China, the sensitivity of orthopaedic surgeons to the secondary prevention of fragility fractures is relatively low. Implementation of a comprehensive prevention approach and targeted continuing medical education are required to encourage surgeons to take greater responsibility for screening, treating, educating, and following their patients with fragility fractures.
Self-Reported Marijuana Use Is Associated with Increased Use of Prescription Opioids Following Traumatic Musculoskeletal Injury
Authors: Bhashyam Abhiram R. , Heng Marilyn , Harris Mitchel B. , Vrahas Mark S. , Weaver Michael J.
Published: January 2019

Background:

Cannabinoids are among the psychoactive substances considered as alternatives to opioids for the alleviation of acute pain. We examined whether self-reported marijuana use was associated with decreased use of prescription opioids following traumatic musculoskeletal injury.

Methods:

Our analysis included 500 patients with a musculoskeletal injury who completed a survey about their marijuana use and were categorized as (1) never a user, (2) a prior user (but not during recovery), or (3) a user during recovery. Patients who used marijuana during recovery indicated whether marijuana helped their pain or reduced opioid use. Prescription opioid use was measured as (1) persistent opioid use, (2) total prescribed opioids, and (3) duration of opioid use. Persistent use was defined as the receipt of at least 1 opioid prescription within 90 days of injury and at least 1 additional prescription between 90 and 180 days. Total prescribed opioids were calculated as the total morphine milligram equivalents (MME) prescribed after injury. Duration of use was the interval between the first and last opioid prescription dates.

Results:

We found that 39.8% of patients reported never having used marijuana, 46.4% reported prior use but not during recovery, and 13.8% reported using marijuana during recovery. The estimated rate of persistent opioid use ranged from 17.6% to 25.9% and was not associated with marijuana use during recovery. Marijuana use during recovery was associated with increases in both total prescribed opioids (regression coefficient = 343 MME; 95% confidence interval [CI] = 87 to 600 MME; p = 0.029) and duration of use (coefficient = 12.5 days; 95% CI = 3.4 to 21.5 days; p = 0.027) compared with no previous use (never users). Among patients who reported that marijuana decreased their opioid use, marijuana use during recovery was associated with increased total prescribed opioids (p = 0.008) and duration of opioid use (p = 0.013) compared with never users.

Conclusions:

Our data indicate that self-reported marijuana use during injury recovery was associated with an increased amount and duration of opioid use. This is in contrast to many patients’ perception that the use of marijuana reduces their pain and therefore the amount of opioids used.

Level of Evidence:

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Opioids in Arthroplasty
Authors: Agrawal Yuvraj , Smith R. Malcolm , Garbuz Donald S. , Masri Bassam A.
Published: January 2019

➤ From 1999 to 2016, >200,000 people died in the U.S. from overdoses related to prescription opioids.

➤ Pain is a cognitive, emotional, and behavioral response to nociception. Maladaptive behaviors, such as pain catastrophizing, interfere with the patient’s ability to cope with pain.

➤ Less adaptive coping strategies such as catastrophic thinking lead to greater pain intensity for a given nociception.

➤ Preoperative or postoperative opioid use for a prolonged period is associated with a higher risk of dependency and death.

➤ Prolonged use of opioid medication in the perioperative period is also associated with revision surgery in arthroplasty.

➤ Family physicians and orthopaedic surgeons are urged to review their prescription practices; to develop guidelines for responsible prescription management, with upper limits set on opioids; and to have a clearly understood and agreed-on pain management program for each patient.
Extended Oral Antibiotic Prophylaxis in High-Risk Patients Substantially Reduces Primary Total Hip and Knee Arthroplasty 90-Day Infection Rate
Authors: Inabathula Avinash , Dilley Julian E. , Ziemba-Davis Mary , Warth Lucian C. , Azzam Khalid A. , Ireland Philip H. , Meneghini R. Michael
Published: January 2019

Background:

Total joint arthroplasty (TJA) episodic payment models shift risk and cost of periprosthetic joint infection (PJI) to surgeons and hospitals, causing some to avoid treating high-risk patients. Furthermore, there are little data to support optimization of host factors preoperatively to decrease PJI, and recent literature supports using extended antibiotic prophylaxis following reimplantation TJA. The purpose of this study was to evaluate whether extended oral antibiotic prophylaxis minimized PJI after primary TJA in high-risk patients.

Methods:

A retrospective cohort study was performed of 2,181 primary total knee arthroplasties (TKAs) and primary total hip arthroplasties (THAs) carried out from 2011 through 2016 at a suburban academic hospital with modern perioperative and infection-prevention protocols. Beginning in January 2015, extended oral antibiotic prophylaxis for 7 days after discharge was implemented for patients at high risk for PJI. The percentages of patients diagnosed with PJI within 90 days were identified and compared between groups that did and did not receive extended oral antibiotic prophylaxis, with p ≤ 0.05 indicating significance.

Results:

The 90-day infection rates were 1.0% and 2.2% after the TKAs and THAs, respectively. High-risk patients without extended antibiotic prophylaxis were 4.9 (p = 0.009) and 4.0 (p = 0.037) times more likely to develop PJI after TKA and THA, respectively, than high-risk patients with extended antibiotic prophylaxis.

Conclusions:

Extended postoperative antibiotic prophylaxis led to a statistically significant and clinically meaningful reduction in the 90-day infection rate of selected patients at high risk for infection. We encourage further study and deliberation prior to adoption of a protocol involving extended oral antibiotic prophylaxis after high-risk TJA, with the benefits weighed appropriately against potential adverse consequences such as increasing the development of antimicrobial resistance.

Level of Evidence:

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
The Association of Body Mass Index with Risk of Long-Term Revision and 90-Day Mortality Following Primary Total Hip Replacement
Authors: Mouchti Sofia , Whitehouse Michael R. , Sayers Adrian , Hunt Linda P. , MacGregor Alexander , Blom Ashley W.
Published: January 2019

Background:

The influence of obesity on outcomes following total hip replacement is unclear. Restriction of total hip replacement on the basis of body mass index (BMI) has been suggested. The purpose of this study was to assess the influence of BMI on the risk of revision and 90-day mortality.

Methods:

This was a population-based, longitudinal cohort study of the National Joint Registry (NJR) for England, Wales, Northern Ireland and the Isle of Man. Using data recorded from April 2003 to December 2015, linked to Office for National Statistics data, we ascertained revision and 90-day mortality rates following primary total hip replacement by BMI category. The probability of revision was estimated using Kaplan-Meier methods. Associations of BMI with revision and mortality were explored using adjusted Cox proportional hazards regression models.

Results:

We investigated revision and 90-day mortality among 415,598 and 413,741 primary total hip replacements, respectively. Each data set accounts for approximately 52% of the total number of recorded operations in the NJR. Thirty-eight percent of the patients were classified as obese. At 10 years, class-III obese patients had the highest cumulative probability of revision (6.7% [95% confidence interval (CI), 5.5% to 8.2%]), twice that of the underweight group (3.3% [95% CI, 2.2% to 4.9%]). When the analysis was adjusted for age, sex, American Society of Anesthesiologists [ASA] grade, year of operation, indication, and fixation type, compared with patients with normal BMI, significantly elevated hazard ratios (HRs) for revision were observed for patients in the BMI categories of class-I obese (≥30 to <35 kg/m2) (HR, 1.14 [95% CI, 1.07 to 1.22]), class-II obese (≥35 to <40 kg/m2) (HR, 1.30 [95% CI, 1.19 to 1.40]), and class-III obese (≥40 to ≤60 kg/m2) (HR, 1.43 [95% CI, 1.27 to 1.61]) (p < 0.0005 for all). Underweight patients had a substantially higher cumulative probability of 90-day mortality (1.17%; 95% CI, 0.86% to 1.58%) compared with patients with normal BMI (0.43%; 95% CI, 0.39% to 0.48%). The risk of 90-day mortality was significantly higher for the underweight group (HR, 2.09 [95% CI, 1.51 to 2.89]; p < 0.0005) and significantly lower for patients who were categorized as overweight (HR, 0.70; 95% CI, 0.61 to 0.81; p < 0.0005), class-I obese (HR, 0.69 [95% CI, 0.59 to 0.81]; p < 0.0005), and class-II obese (HR, 0.79 [95% CI, 0.63 to 0.98]; p = 0.049) compared with patients with normal BMI.

Conclusions:

Although long-term revision rates following total hip replacement were higher among obese patients, we believe that the rates remained acceptable by contemporary standards and were balanced by a lower risk of 90-day mortality.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
The Evolution and Interpretation of the Gustilo and Anderson Classification
Authors: Yim Guang H. , Hardwicke Joseph T.
Published: January 2019

Background:

The Gustilo classification is the most established system for classifying open fractures. Despite this, the classification has changed in how it has been described and interpreted. We have traced how this classification has slowly evolved throughout the literature over the past 4 decades.

Methods:

A systematic search of the literature was undertaken with the MEDLINE, Embase, and PubMed databases to source relevant articles that have evolved the interpretation of the Gustilo classification. The references from these articles were consecutively hand-searched to find other articles that describe the Gustilo classification.

Results:

There was a total of 393 results from the Healthcare Databases Advanced Search (HDAS): 95 from MEDLINE, 49 from Embase, and 249 from PubMed. Fifty-six articles were initially selected; an additional 67 articles were retrieved through reference checking and further checking of relevant articles until no additional relevant articles could be found.

Conclusions:

The original Gustilo and Anderson classification initially was modified by Gustilo before subtle changes were made to the descriptors in the 1990s. Some authors have used the Gustilo classification to create alternative classifications, but these have not gained traction. Other contemporaneous literature has modified the Gustilo-IIIB subtypes to better stratify functional and reconstructive outcomes following vascular injury. The impact and longevity of such recent modifications are yet to be known.
The Use of a Self-Administered Questionnaire to Reduce Consultation Wait Times for Potential Elective Lumbar Spinal Surgical Candidates
Authors: Coyle Matthew J. , Roffey Darren M. , Phan Philippe , Kingwell Stephen P. , Wai Eugene K.
Published: January 2019

Background:

In a public health-care system, patients often experience lengthy wait times to see a spine surgeon for consultation, and most patients are found not to be surgical candidates, thereby prolonging the wait time for those who are. The aim of this study was to evaluate whether a self-administered 3-item questionnaire (3IQ) could reprioritize consultation appointments and reduce wait times for lumbar spinal surgical candidates.

Methods:

This prospective, pragmatic, blinded, randomized controlled quality improvement study was conducted at a single Canadian academic health-care center. This study enrolled 227 consecutive eligible participants with an elective lumbar condition who were referred for consultation with a spine surgeon. All participants were mailed the 3IQ after their referral was received. Patients were randomized into the intervention group, in which leg-dominant pain reported on the 3IQ resulted in an upgrade in priority to be seen, or into the control group, in which no change to wait-list priority occurred. The main outcome measured was time to consultation for participants who were deemed surgical candidates following consultation.

Results:

There were no significant differences between groups with regard to demographics, overall group wait times, proportion of surgical candidates, or disability. A total of 33 patients were deemed surgical candidates after consultation. The median wait from referral to consultation was shorter for the 16 surgical candidates in the intervention group (2.5 months; interquartile range [IQR]: 2.0 to 4.8 months) compared with the 17 surgical candidates in the control group (4.5 months; IQR: 3.4 to 6.9 months; p = 0.090). The odds of seeing a surgical candidate within the acceptable time frame of 3 months were 5.4 times greater (95% confidence interval: 1.2 to 24.5 times; p = 0.024) in the intervention group.

Conclusions:

The use of a simple, self-administered questionnaire to reprioritize referrals resulted in shorter consultation wait times for patients who required a surgical procedure and significantly increased the number of surgical candidates seen within the acceptable time frame. It may be valuable to consider adding the 3IQ to clinical care practices to better triage these patients on waiting lists.
Identification of Areas of Epiphyseal Cartilage Necrosis at Predilection Sites of Juvenile Osteochondritis Dissecans in Pediatric Cadavers
Authors: Tóth Ferenc , Tompkins Marc A. , Shea Kevin G. , Ellermann Jutta M. , Carlson Cathy S.
Published: January 2019

Background:

The pathogenesis of human juvenile osteochondritis dissecans (JOCD) remains poorly understood, with multiple factors implicated, including ischemia, repetitive trauma, and genetic predisposition. Similarities in the predilection site and the diagnostic and clinical features of JOCD to the well-characterized veterinary counterpart, osteochondrosis dissecans, suggest that, similar to the animal disease, the pathogenesis JOCD may also be initiated in the first few years of life, when disruption of blood supply to the epiphyseal growth cartilage leads to failure of endochondral ossification. To gather data in support of the hypothesis that JOCD and osteochondrosis dissecans have a shared pathogenesis, biopsy specimens obtained from predilection sites of JOCD in juvenile human cadavers were histologically examined to determine whether they contained lesions similar to those found in animals diagnosed with subclinical osteochondrosis dissecans.

Methods:

In this descriptive laboratory study, 59 biopsy specimens (6 mm in diameter) were harvested from the central aspect (i.e., the notch side) of the femoral condyles of 26 human cadavers (1 month to 11 years old). Specimens were histologically evaluated for the presence of areas of cartilage necrosis and the morphology of cartilage canal blood vessels.

Results:

Locally extensive areas of necrotic epiphyseal cartilage were identified in 4 specimens obtained from 3 donors (ages 2 to 4 years). Areas of cartilage necrosis accompanied by focal failure of endochondral ossification or surrounded by subchondral bone were identified in biopsy specimens from 4 donors (ages 4 to 9 years).

Conclusions:

The identification of epiphyseal cartilage necrosis identical to that described in animals with subclinical osteochondrosis, found in biopsy specimens obtained from femoral predilection sites of JOCD in pediatric cadavers, suggests a shared pathogenesis of JOCD in humans and osteochondrosis dissecans in animals.

Clinical Relevance:

These findings imply that the pathogenesis of human JOCD likely starts 5 to 10 years prior to the development of clinical symptoms. Enhanced understanding of the temporal features of JOCD pathogenesis provides an opportunity for earlier diagnosis and treatment, likely resulting in improved outcomes for this condition in the future.
Monitoring of BALB/C strain mice health, investigation of behavior, hematological parameters under the effect of an electromagnetic field
Authors: ZYMANTIENE JUDITA , ZELVYTE RASA , JUOZAITIENE VIDA , OBERAUSKAS VAIDAS , NOREIKA ALGIS , JUODZIUKYNIENE NOMEDA , ANIULIENE ALBINA
Published: January 2019

The aim of this study was to investigate the effect of electromagnetic fields on BALB/c strain mice on their health, body weight, behavior characteristics, hematological parameters and histopathological findings in the brain. The mice of the experimental groups were exposed to electromagnetic waves by using Nokia 230 and Samsung 19300 Galaxy S III mobile phones situated at 2 cm from the cages. In the present study, it can be concluded that the exposure of mice to mobile phone radiation had an effect on the structure of the brain, behavior and body weight. The waves of mobile phones increased activity characteristics and changed some behavioral categories of mice and also decreased their body weight. Histopathological examination revealed mild edema of neutrophils and degeneration of some neurons and glial cells in the brains of experimental mice. The results of the present study showed that a using mobile phone had an influence on in vivo systems.
Morphometric and histopathologic evaluation of the effects of cloprostenol and equine chorionic gonadotropin administration on the reproductive organs of female rats
Authors: GÜRLER HANDE , DEMIREL MÜRŞIDE AYŞE , KARACA EFE , ACAR DUYGU BAKI , AKÇAY AYTAÇ , GÜLBAHAR MUSTAFA YAVUZ
Published: January 2019

The aim of this study was to determine the short-, mid- and long-term effects of cloprostenol (a synthetic analogue of prostoglandin F2α, PG) and equine chorionic gonadotropin (E) administration on reproductive organs (uterine tissue and ovaries) in female rats. Three different groups, PG, E, and control (C), were created, as well as six subgroups of the PG and E groups. After the treatment procedure, reproductive organs were removed surgically 7, 14, and 21 days after the last injection. Morphometric and histopathological changes in tissues were evaluated. It was shown that PG and E had a moderate proliferative effect on epithelial cells and endometrial glands, especially in the mid-term. It was also observed that, regardless of the time of application, some pathological changes can result from hormone administration.
Analysis of correlation between the detection rate of Mycoplasma hyopneumoniae in slaughter pigs and season, climate change, and presence of lung lesions
Authors: LI RUNCHENG , HU YULI , GE MENG , ZHAO DUN , YANG TAOTAO , QING RENKE , YU XINGLONG
Published: January 2019

The purpose of this study was to analyze the correlation of the rate of Mycoplasma hyopneumoniae (M. hyo) in slaughter pigs with season, climate change and enzootic pneumonia (EP) lesions. We collected 530 slaughter pig lungs with suspected lesions from two slaughterhouses in different seasons and weather conditions from November 2014 to March 2017 in Changsha Hunan Province, China. The EP lesions of these lungs were quantified, and a PCR analysis was used to detect M. hyo in samples of bronchoalveolar lavage fluid (BALF). Twenty percent, 10%, and 9% of the lung specimens were scored 1-5, 6-10, and ≥ 11, respectively. Additionally, we found that 36% of all BALF samples tested positive for M. hyo. Among the lung specimens collected in winter, 41% scored 1 or more, and 53% tested positive for M. hyo. With respect to seasons, the lung specimens collected in summer showed the least number of EP lesions and the lowest positive testing rate for M. hyo. Of these specimens, 27% scored 1 or more, and 22% tested positive for M. hyo. Additionally, low temperature and fast temperature change (during 10 days before sampling) were associated with a higher rate of M. hyo detection in BALF. There was a positive correlation between the lung EP lesion score and the detection rate of M. hyo in the BALF of slaughter pigs. In conclusion, lung EP lesion scoring in slaughter pigs is of referential value to the evaluation of the dynamics of M. hyo infection in a swine population. It is essential to control the spread of M. hyo by careful management of swine populations, and the prevention and control of M. hyo in fattening pigs is of great significance to the eradication of the disease.
Effect of dietary phyto-humic preparations on lipids indices of commercial laying hen eggs
Authors: BUBEL FABIOLA , DOBRZAŃSKI ZBIGNIEW , GRELA EUGENIUSZ R. , BOBAK ŁUKASZ , OZIEMBŁOWSKI MACIEJ
Published: January 2019

The aim of the study was to determine the effect of three different phyto-humic feed preparations on the basic qualitative characteristics of eggs, i.e. total cholesterol content and fatty acid profile of the yolk. The study was carried out on 80 Lohmann Brown (LB) laying hens in an experimental facility with a floor maintenance system on a straw bedding (5 layers/m2). A control group (K) and three experimental ones (A, B, C), with 20 birds in each (in separate pens), were created. The birds were placed in the 16th week of life, while the experimental preparations were introduced in the 22nd week of life and were administered for 43 weeks (constant 3% addition to the feed mixture).The following preparations were applied: humic-peat (H-t) in group A, humic-herbal (H-z) in group B, and humic-lucerne (H-1) in group C. The eggs for the study were collected three times, 30 eggs from each group in the following periods: 1st series – 31st week of life (peak of laying period); 2nd series – 54th week of life (later phase of laying period) and 3rd series – 65th week of life (final phase of laying period). Six samples (mean of 5 well-mixed yolks) from each group in three laying periods (360 eggs were used in total) were prepared for laboratory analyzes (lipids examination). Laboratory analyzes were performed using a chromatograph – Finnigan Focus PolarisQ manufactured by Thermo Electron with capillary columns: HP-88 by Agilent J&W (fatty acids) and Rtx-1MS by Restek (cholesterol). The applied phytohumic preparations – but only those with a share of dried lucerne or herbs – significantly (p ≤ 0.05) reduced total cholesterol content, especially in group C (10.88 mg/g yolk) compared to group K (11.94 mg/g yolk). All preparations positively influenced the fatty acids profile of yolk; there was a significant (p ≤ 0.05) increase in the concentration of n-3 PUFAs (max 2.84% in the group B), the n-6/n-3 ratio decreased significantly (most beneficial 8.33 in group B), and lipids quality improved: atherogenic index (AI) decreased significantly (p ≤ 0.05) in group A (0.32) and thrombogenic index (TI) was a significantly (p ≤ 0.05) lower in all experimental groups (0.83 – 0.84) compared to group K (0.36 and 0.87 respectively). Dietary phyto-humic preparations increased the nutritional and dietary value of hen eggs.
VAN - HAKKÂRİ İLLERİ KÜLTÜR VE SANATINDA KUŞLAR
Authors: BUĞRUL Hasan
Published: January 2019

Van ve Hakkâri illeri sanat ve kültürü
irdelendiğinde kuşların bunlarda büyük bir yere sahip olduğunu söyleyebiliriz.
Tarihi eser olarak Akdamar Kilisesi ve Yedikilise Manastırı bu yönüyle dikkat
çekerler. Figürlerine yer verilen kuşlar arasında bölgede rastlanılan türler
yanında “tavus” kuşu gibi bölgede rastlanılmayan kuş türlerini de görmekteyiz.
Dokuma ve örgü eserler üzerinde de sıkça kuş figürlerine rastlanmaktadır.
Kültürel etkileşimde insanların farklı yönleriyle kuşlara benzetilmesine sıkça yer
verilmektedir. Bu anlamda; kartal, turna, bülbül, hüthüt, kaya güvercini,
leylek, kınalı keklik, suna, karga ve serçe gibi kuşlar öne çıkmaktadır.
Yapılan araştırmalarda, Van-Hakkâri yöresi kültür ve sanatında kuşların etkisi
ile bağlantılı detaylı bir çalışmaya rastlanılmamıştır. Bu çalışma ile bu
alandaki boşluğun doldurulması ve yörenin kültür, sanat ve turizmine katkıda
bulunulması hedeflenmiştir.
Obowiązki organów administracji publicznej w zakresie przetwarzania danych w systemach zinformatyzowanych przed i po wejściu w życie RODO i nowelizacji ustawy o ochronie danych osobowych
Authors: Skoczylas Dominika
Published: January 2019

Celem artykułu jest wskazanie konsekwencji prawnych w zakresie dotyczącym zapewnienia bezpieczeństwa przetwarzania danych osobowych w systemach zinformatyzowanych. Ustawodawca wyznaczył administratorom danych osobowych, konkretne obowiązki w kwestii ustalenia odpowiednich środków organizacyjnych, osobowych, rzeczowych i technicznych, które mają uniemożliwić posługiwanie się danymi osobowymi przez nieuprawnione podmioty w nielegalnym celu. Od maja 2018 r. obowiązuje Rozporządzenie Parlamentu Europejskiego i Rady 2016/679 o ochronie danych osobowych. Wprowadza nowe regulacje prawne np. ustanawia inspektora ochrony danych. Pierwsza część artykułu wskazuje zadania administratorów danych polegające na użyciu środków zabezpieczających dane osobowe w systemach zinformatyzowanych, przed wejściem w życie RODO i ustawy z 10.5.2018 r. o ochronie danych osobowych. W drugiej zawarto najważniejsze zmiany odnoszące się do administratorów danychosobowych, określone w RODO i ustawie o ochronie danych osobowych. Metody badawcze obejmują komparatystyczną analizę podstawowych tekstów aktów prawnych z wykorzystaniem literatury przedmiotu (zastosowano metodę porównawczo-prawną).
Definicje normatywne biopaliw ciekłych i biokomponentów oraz ich wzajemne zależności
Authors: Kruk Artur
Published: January 2019

Głównym celem artykułu jest scharakteryzowanie definicji normatywnych biopaliw ciekłych oraz biokomponentów, a także wzajemnych zależności i ich wpływu na obowiązki reglamentacyjne wytwarzania obu tych substancji i inne aspekty normatywne i pozanormatywne dotyczące tych sektorów. Podjęty problem jest niezwykle złożony, pozostaje przedmiotem zainteresowania wielu dyscyplin, a ponadto omawiane przepisyzawierają pewną sprzeczność, która może powodować obejścia prawa lub nieporozumienia interpretacyjne. Ważna jest więc możliwie jak najszersza analiza przytoczonych zagadnień, dlatego w artykule zostaną wskazane nie tylko odpowiednie akty prawne, ale także niezbędne informacje technologiczne oraz ekonomiczne, oddające istotę zagadnienia.
Food Hygiene at On-Site Premises in Perak and Selangor: Are We Ready for Self-Regulatory Practices?
Authors: Saad Mazni , Ong Mohd Hanafi Azman , Osman Noor Suzana , Abdullah Norhidayah
Published: January 2019

Safe and hygienic food add value to food intake and prevent undesirable health conditions. Food handlers who are at the forefront of the food service process must monitor and measure the standards of their food hygiene and its preparation and cooking practices. This study investigates how ready food handlers at on-site premises are for self-regulatory practices. Food surface contacts were chosen for investigation via purposive sampling and swab analysis to unravel hidden messages about the level of hygiene standards in the foodservice operation. The findings reveal the existence of contamination across the majority of the selected contact surfaces that could affect the consumers’ well-being and quality of life.Keywords: consumer well-being; food hygiene; food surface contact; food handler; the on-site premise eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1568
Creating Positive Environment for Autism Using Sensory Design
Authors: Ghazali Roslinda , Md Sakip Siti Rasidah , Samsuddin Ismail
Published: January 2019

The designated learning environment for autism should consider sensory issues to overcome their needs. This paper would review related articles to gain a better understanding of autism needs regarding sensory design, sensory issues, sensory space, internal environment, and physical learning environment. This paper will outline the sensory design of the physical learning environment that would impact by the sensory design towards the physical learning environment. This research paper would be a guide for the designer to overcome sensory input so that autistic can learn more efficiently and develop with less stress.Keywords: Autism; sensory design; sensory issues; physical learning environment;eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1618
Illness Perception of Patients with Familial Hypercholesterolaemia varies with Level of Education and Presence of Cardiovascular Disease
Authors: Razali Salmi , Ismail Zaliha , Abdullah Najib , Nawawi Hapizah M
Published: January 2019

Illness perception determines the healthy lifestyle of patients with Familial Hypercholesterolaemia (FH). Despite the availability of advanced treatment and preventive measures, there is still sparse data on illness perception of FH patients. Hence, this study aimed to describe the illness perception of FH patients and investigate its association with sociodemographic and illness-related factors. 100 FH patients were assessed using Pro forma questionnaires and revised illness perception questionnaire (IPQ-R). Illness perception of FH patients varies according to the level of education and the presence of cardiovascular disease (CVD). These findings may help clinicians to improve the interventions suitable for FH patients. Keywords: Familial hypercholesterolaemia; illness perception; sociodemography; cardiovascular diseaseeISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1620
Quality of Life and Its Contributing Factors in Patients with Familial Hypercholesterolaemia in Malaysia
Authors: Razali Salmi , Ismail Zaliha , Chua Yung An , Nawawi Hapizah M
Published: January 2019

Familial hypercholesterolaemia (FH) causes severe complications including cardiovascular diseases (CVDs) and stroke, leading to poor quality of life (QoL). Despite the availability of advanced treatment, data on QoL and its contributing factors is sparse. Hence, this study aimed to describe the pattern of QoL among FH patients and investigate its association with sociodemographic factors and illness characteristics. Hundred FH patients were assessed using Pro forma questionnaires and World Health Organization QoL questionnaire (WHOQOL-BREF). Significant contributing factors including level of education, income, and the presence and type of CVDs. These findings may help to inform more effective interventions for FH patients. Keywords: Familial hypercholesterolaemia; quality of life; sociodemography; cardiovascular diseaseeISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1621
Barriers for blood donation in non-blood donor: a qualitaive study
Authors: Mohd Asmawi Ummi Mohlisi , Osman Maznah , Said Norimah , Mohammad Mariam
Published: January 2019

Donating blood is a noble act that serves a humanitarian cause. This study aims to explore the barriers from donating blood amongst non-donors. Four focus group discussions (FGD) were conducted amongst non-blood donors. The discussions were carried out in the local language, and the verbatim was translated into English. Most of the participants were aware of the importance of donating blood to save other people. Fear is the most factors that hinders them from becoming a blood donor. The participants recommended the use of advertisements that could stir an emotional reaction. Blood banks should hence organise more blood donation campaigns to spread the awareness in the community.Keywords: awareness; blood donation; blood bank; focus group discussioneISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1622
Street Vending in Urban Street Corridor in Medan, Indonesia: Potency or Problem?
Authors: Zahrah Wahyuni , Nasution Achmad Delianur
Published: January 2019

This paper is aimed to investigate the role of street vending to support public life in the urban street. The study took place in three shop houses corridors in Medan, i.e., Asia, Kapten Muslim, and Ring Road Corridor. The research used the descriptive-exploratory method that collected qualitative and quantitative data. The exploration found that the street vending spots became the only place for social interaction, but not so intensive. The study pointed out to accommodate the street vending in a particular space of the corridor, in line with the re-arrangement of the whole area of the street to be a more human-friendly public space.Keywords: street vending; urban street; public life; MedaneISSN: 2398-4287© 2019. The Authors. Published for AMER ABRA cE-Bsby e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, UniversitiTeknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1623
Inhibitory Effect of Rhodomyrtus tomentosa Methanolic Leaves Extract on P-selectin Platelet Aggregation of ABO Blood Group by ELISA Method
Authors: Kamarudin Evana , Megat Ismail Nur Fadhillah , Ismail Siti Norul Fatin
Published: January 2019

In light of discovering the new antiplatelet from the natural source, this study was undertaken to determine the inhibitory effect of Rhodomyrtus tomentosa methanolic leaves extracts on P-selectin platelet aggregation of the ABO blood group. Whole blood samples from each blood group were collected tested with different concentration of leaves extract by using ELISA method. The inhibition was considered to occur if the values of concentration P selectin detected below 1.56 ng/ml. Instead of inhibiting the P-selectin expression as antiplatelet, Rhodomyrtus tomentosa accelerates the P-selectin expression as an agonist in a dose-dependent manner. In conclusion, no antiplatelet effects were seen.Keywords: P-selectin, Rhodomyrtus tomentosa, platelet aggregation, ABO Blood GroupeISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1626
The Effect of Preoperative Neutrophil-Lymphocyte Ratio On Quality of Life After Coronary Artery Bypass Graft (CABG) Surgery
Authors: Kamal Fatmawati , Awg Isa Raihan , Khalid Zalizah , Mohd Asmawi Ummi Mohlisi
Published: January 2019

Neutrophil-lymphocyte ratio (NLR) is an inexpensive and easily accessible inflammatory biomarker. Studies have shown the ability of NLR to predict poor outcome in many diseases. This study aimed to determine the relationship between NLR and cardiovascular risk factors, and duration of ICU and hospital stay in post CABG patients. 137 patients who underwent CABG between 2013 and 2017 with available preoperative neutrophil and lymphocyte counts were included in the study. NLR was found to be increased in patients who had prolonged intensive care unit (ICU) stay and hospital/ ward stay. Thus NLR can potentially be used to predict worse outcome.Keywords: Neutrophil-lymphocyte ratio; coronary artery bypass graft (CABG); mortality; length of stay (maximum 4 keywords) eISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1628
Flood Hazard Information Map Using Geographical Information System (GIS) For Residential Community Resilience
Authors: Zulkarnain Siti Hafsah , Muhammad Yuzir Muhamad Ali , Razali Muhammad Najib , Tarmidi Zakri
Published: January 2019

The purpose of this research is to develop the residential flood hazard information map using Geographical Information System (GIS) for residential community resilience. The review approach is based on related literature contributing to identifying themes such as “flood hazard information map” and “geographical information system”. Integration of data will be sourced from Department of Irrigation and Drainage (DID), National Property Information Centre (NAPIC) and Jabatan Ukur dan Pemetaan Malaysia (JUPEM) using Unique Parcel Identifier (UPI) for respective residential land parcels. An extensive review of previous studies of flood hazard information map of residential community resilience for different flood disaster studies is considered to be the main restrictive factor resulting in a lack of empirical studies in this field. The development of residential property needs to be imposed with the elements for building specifications and materials that have flood resistance and resilience to protect the community life and property.Keywords: Community resilience, Floods, Geographical Information System (GIS), Residential propertyeISSN: 2398-4287 © 2019. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v4i10.1632
Informing the Digital Archive with Altmetrics
Authors: Taylor Ashley L , Collister Lauren B
Published: January 2019

Altmetrics can be used to understand impact beyond citations, particularly for digitized collections. As cultural institutions look to pursue more active engagement with communities of practice, altmetrics help archivists understand the conversations happening in real time that will allow them to provide access to the most relevant materials. Through the use of case studies, we aim to demonstrate how applying altmetrics while considering the curation of digital collections can allow archivists to stay engaged with target communities outside traditional channels, demonstrating both the applicability of altmetrics to legacy scholarly work and the value of digitization as an access method.
The negative impact of illegal gold mining on the environmental sector in Batang Asai, Jambi
Authors: Susanti Try , Utami Wiji , Hidayat Hidayat
Published: January 2019

The negative impact of Illegal Gold Mining / IGM on the environmental sector in Batang Asai District, Sarolangun Regency, Jambi was investigated through a descriptive qualitative method. The purpose of this study was to determine the negative impact of IGM activities to several ecosystems, the effect of IGM on community activities, and some efforts to reduce IGM. The instruments of data collection included observation, interviews, and documentation. Data were analysed through data reduction, data presentation, and conclusion withdrawal. The results showed that IGM activity had a negative impact on the environment namely noise pollution, dust, degradation on the quality of Batang Asai River, forest conversion, river siltation, the emergence of large holes, overburden, soil abrasion, the disappearance of Meranti plants (Shorea sp. ) and Damar (Agathis Damara). Besides that, other impacts were the declining population of Semah Fish (Tor sp.) which had become the special characteristic of fish in the area. Some efforts were made by the government to overcome and foster IGM activities, e.g. by providing counselling and sanctions in a judicial and non-judicial manner that was carried out continuously.