bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Price, Positioning and Cafe Atmosphere on Consumer Satisfaction at the Janji Jiwa Cafe, Sorong City
Authors: Ratnawati Ratnawati , Bintari Wisang Candra , Mufti Digor , Rawi Rais Dera Pua
Published: July 2022

This research aims to determine if The Price, Positioning, and Suasnaa Cafe affect Customer Satisfaction at the Promise Jiwa Cafe Sorong City. The method used in this study is the quantitative method with descriptive and correlation approaches. The data was obtained by sharing questionnaires with 80 respondents—sampling techniques using the Purposive Sampling technique. The data analysis method uses multiple linear regression analysis of hypothesis testing (t-test, f-test, and determination coefficient). Researchers tested the primary data in this study by using the spss application program version 20 for windows and secondary data. The results of the research data analysis showed that price had a positive and significant effect on Consumer Satisfaction of 9.467 with a probability of 0.000. The positioning has a positive and significant effect on Consumer Satisfaction of 6,039 with a probability of 0.000. Cafe atmosphere has a positive and significant effect on Customer Satisfaction of 8,150 with a probability of 0.000. Price, Positioning, and Atmosphere Cafe are influential together (simultaneously). It indicates that all variables have a partially significant effect.
Social Modality for Post Flood Disaster Cimanuk River in Garut Regency
Authors: Kristian Indra , Purwanto Bambang Heru , Azis Yaya Mulyana Abdul
Published: July 2022

Based on the observation that the implementation of Disaster Management in Garut Regency has not been implemented optimally. This is evident from the fact that there are still many victims when a disaster occurs so that overall handling is still necessary. The research method used is qualitative. The type of qualitative approach used is descriptive. Qualitative research is a research procedure that produces descriptive data in written or spoken words from people and observable behavior. The qualitative method was chosen considering that this method is expected to obtain accurate data and examine research problems in depth so that the expected results can be obtained. The term gotong royong cannot be underestimated in a foreign language because gotong royong is the familiar spirit of the Indonesian people to unite, cooperate, share, help each other, and feel together to achieve common goals with benefits for all. The term gotog royong is often heard, but this social spirit is starting to weaken, especially in cities. Restoring the spirit of gotong royong today is quite a challenge today. However, participation and participation in a community group are the key to life's values to carry out a strategy in life.
Implementation of the Policy for the Implementation of the Bekasi City Regional Health Insurance Program
Authors: Prastiwi Ellya Niken , Alamsyah Kamal , Salamah Ummu
Published: July 2022

The main problem in this research is that the policy/program of Regional Health Insurance Based on Family Cards and Population Identification Numbers has not been effectively implemented in Bekasi City. The research method used by the researcher is descriptive analysis with a qualitative research approach. This method and approach was chosen with the consideration that it is hoped that real data can be obtained and are able to examine the research problem in depth so that the expected results can be obtained. The results of the study can be explained that there are factors in implementing the Bekasi City Regional Health Insurance policy, namely standard factors, policy measures and objectives, policy measures and objectives, resources, characteristics of implementing organizations, attitudes of implementers, communication between related organizations and activities. - implementation activities, and the social, economic and political environment. However, in its implementation, these factors have not been fully implemented effectively, namely the policy resource factor and the characteristic factor of the implementing agency so that there are still problems encountered related to the implementation of the Regional Health Insurance policy. This of course also has not been able to provide the best way in providing quality public services, especially with regard to the Regional Health Insurance Program for the Community Based on Family Cards and Population Identification Numbers.
Sampling dalam Penelitian Kesehatan
Authors: Abdul Wahab
Published: July 2022

Tulisan ini mengemukakan rincian populasi dan sampel sekaligus random sampling dan non-random sampling. Sampling yang dapat digunakan dalam penelitian bidang kesehatan meliputi: simple random sampling, proporsionate stratified random sampling, disproportionate stratified random sampling, dan cluster random sampling, sedang non-random sampling terdiri dari sistematis sampling, aksidental sampling, quota sampling, purposive sampling, exhaustive sampling, snowball sampling, consecutive sampling, dan expert sampling.
Compendio de Medicina Interna
Authors: Janeta Lazo Katherine Estefanía , Buenaño Sarmiento Juan José , Escobar Carrillo Johanna Mariana , Acosta Andrade Ana Cristina , Montenegro Loja Maritza Fernanda , Cañar Calderón Diego Javier , Culqui Herrera Rosa Yolanda , Prieto Cuesta Emma Divanna , Medina Llerena María Fernanda , Pérez Rodríguez María Renata , Pauta Moreno Geovanny Fabricio , Tulcanaza Ochoa Galo Fernando , Soto Silva Gustavo Alberto , Arias Carvajal Saira Marlene , Riofrio Andaluz Edison Santiago , Machuca Córdova Liliana Maribel , Pino Vaca Dipaola Pamela , Aguilar Aguilar Madelaine Carolina , Ayavaca Carchi Marcia Jacqueline , Aguirre Garcia Marco Antonio
Published: July 2022

El libro compendio de medicina interna nos ofrece 18 temas de patologías más frecuentes que pueden presentarse en el primer nivel de atención, su descripción, diagnóstico y tratamiento de primera linea. De gran utilidad para médicos que se encuentran realizando sus rotaciones en las diferentes áreas.
Tratado de Pediatría
Authors: Sanga Pintag Dennis Abraham , Garzon Moreta María Paz , Llumiquinga Yar Verónica Gabriela , Moreno Castro Franklin Iván , Pérez Rodríguez María Renata , Padrón Ordóñez Katherine Patricia , López Toledo María Gracia
Published: July 2022

La especialidad de pediatría ofrece diversos retos a los médicos que optan por esta especialidad, en la obra tratado de pediatría se ofrecen los casos mas relevantes de patologías que deben tratarse en el sistema de salud ecuatoriano. Se ofrecen cuando ha sido posible datos de la epidemiología y tratamiento farmacológico del país.
Generalidades de Cirugía Vascular
Authors: Lara Saldaña Carla Alejandra , Guamán Ordóñez Omar Rodrigo , Niato Pacheco Jonathan Fabricio
Published: July 2022

La presente obra presenta la angiología y cirugía vascular como una visión de la especialidad médico-quirúrgica. Se presenta el estudio, prevención, diagnóstico clínico e instrumental y tratamiento de la patología vascular en sus condiciones más comunes.
Effect of Family-Centered Empowerment Model on Knowledge and Caring Performance of Mothers of Children with Leukemia: A Randomized Clinical Trial
Authors: Boshagh Fatemeh , Hakim Ashrafalsadat , Alghasi Arash , Haghighizadeh Mohammad Hosein
Published: July 2022

Background: Today, cancer is one of the leading public health concerns worldwide. Being diagnosed with cancer is not necessarily a life-threatening event for children and their families. Objectives: In this view, this study was done to determine the impact of family empowerment programs on the knowledge and care performance of mothers with leukemia children. Methods: The present study is a randomized clinical trial conducted on 62 mothers of children with cancer who were referred to the oncology wards of some educational hospitals in Ahvaz. The subjects were randomly divided into two intervention and control groups. The education was conducted in five sessions of 45 minutes (two sessions per week). Results: Comparison of the mean score of the knowledge of mothers of children with leukemia before education (3.09) and after education (6.29) was one of the interventions that were significant in the intervention group (P < 0.001), but in the control group, no significant statistical difference was observed. Conclusions: The results of the study indicated that by educating the family through the family-centered empowerment model, it is possible to increase the caregiving knowledge of mothers and prevent chemotherapy complications in children
Left To Lose
Authors: Josephs Anya ,   After Dinner Conversation
Published: July 2022

To what degree is it appropriate to merge social networks with organizational goals in order to extract greater work from your volunteers? In this work of philosophical short story fiction, a young girl hears a voice from behind that promises to fulfill her wishes, but at a price. First, she wishes her abusive father dead, but it comes at the price of falling asleep for a week. Later, she sacrifices her leg in order to prevent the harvest from failing. She finally leaves her home as payment for her parents getting the money from her marriage dowry, while she escapes the unwanted marriage. Homeless, she is discovered by a rebel group fighting against their tyrannical king. They learn about her power and, bit by bit, ask her to sacrifice herself to aid them in their fight. She falls in love with one of the men in the struggle and continues to give more of herself to the fight. She goes blind and loses an arm, all as payment to the voice for favors it will do for her, and for the struggle. Finally, the young girl is asked to make the ultimate sacrifice and pay for a favor from the voice with her life.
My Lengthy Involvement with Polanyi’s Thought
Authors: Mullins Phil , Gulick Walter ,   The Polanyi Society
Published: July 2022

In this interview, Phil Mullins asks Walter Gulick about what originally attracted him to Polanyi’s thought. What aspects has he felt might be improved and/or further developed? What is the ongoing import of Polanyi’s accomplishments, and where does the Polanyi Society go from here?
A new species of Habenaria (Orchidaceae, Asparagales) and a checklist of Orchidaceae from limestone outcrops of Brazil
Authors: Batista João A.N. , Ferreira Vera L. , Alves Camila I.G. , Stehmann João R.
Published: July 2022

Habenaria karstica J.A.N.Bat. sp. nov., a new species from limestone outcrops (i.e., karst) in the State of Minas Gerais, Brazil, is described. The new species is ecologically very distinct since it is the only Neotropical species of the genus that grows on limestone outcrops under full sun, associated with mat-forming saxicolous plants. It is morphologically similar to species of the Habenaria repens complex, and separation is only possible through a combination of morphological characters. Bayesian and parsimony phylogenetic analyses based on nuclear (rDNA ITS, ETS) and plastid (matK-trnK, rps16-trnK) DNA markers revealed that H. karstica belongs to H. sect. Spathaceae. The new species, however, differs in floral morphology from the other species in this clade. A survey of the literature and public plants datasets revealed 122 species and 58 genera of Orchidaceae in karsts of Brazil. Although small compared to the family’s diversity in the country, Orchidaceae is among the families with the highest number of species in some karst localities. Our results indicate that approximately 97% of Orchidaceae found in karsts of Brazil is not limited to limestone outcrops areas, and that species composition of each locality is primarily determined by the regional flora and the biome in which it is located.
Extended-Release Viloxazine for Children and Adolescents With Attention Deficit Hyperactivity Disorder
Authors: Mather Keith , Condren Michelle
Published: July 2022

Non-stimulant medication therapy for children, adolescents, and young adults with attention-deficit/hyperactivity disorder (ADHD) has included alpha 2-agonists (guanfacine and clonidine) as well as a norepinephrine reuptake inhibitor (atomoxetine) for multiple years. Although these may be effective options for some children, they are generally considered to be less effective than stimulant medications. In addition, there has been a suicidal ideation concern in early-late adolescence with atomoxetine, emphasizing the need for continued development of other treatment options.

Extended-release viloxazine (SPN-812) has been shown in phase 2 and phase 3 trials to be an effective, well-tolerated alternative for some children with ADHD. The mechanism of action of viloxazine is unique, modulating activity of both serotonin and norepinephrine. Treatment-related adverse events most commonly seen included somnolence, decreased appetite, and headache. Although continued evaluation to confirm the reduced symptoms of ADHD in children along with the safety profile is needed, extended-release viloxazine may offer a once-a-day pharmaceutical treatment option for patients in which stimulant medication is not effective or not a favorable option. It may also be beneficial for those children and adolescents with a comorbidity of depression.
Targeting Calcineurin Inhibitor–Induced Arterial Hypertension in Liver Transplanted Children Using Hydrochlorothiazide
Authors: Hartleif Steffen , Baier Hannah , Kumpf Matthias , Handgretinger Rupert , Königsrainer Alfred , Nadalin Silvio , Sturm Ekkehard
Published: July 2022

OBJECTIVE

Arterial hypertension (AH) is the most common toxic effect of calcineurin inhibitor (CNI)–based immunosuppression in children after liver transplantation (LT). Activation of the renal sodium chloride cotransporter (NCC) by CNIs has been described as a major cause of CNI-induced AH. Thiazides, for example, hydrochlorothiazide (HCTZ), can selectively block the NCC and may ameliorate CNI-induced AH after pediatric LT.

METHODS

From 2005 thru 2015 we conducted a retrospective, single-center analysis of blood pressure in 2 pediatric cohorts (each n = 33) with or without HCTZ in their first year after LT. All patients received CNI-based immunosuppression. According to AAP guidelines, AH was defined as stage 1 and stage 2. Cohort 1 received an HCTZ-containing regimen to target the CNI-induced effect on the NCC, leading to AH. Cohort 2 received standard antihypertensive therapy without HCTZ.

RESULTS

In children who have undergone LT and been treated with CNI, AH overall was observed less frequently in cohort 1 vs cohort 2 (31% vs 44%; ns). Moreover, severe AH (stage 2) was significantly lower in cohort 1 vs 2 (1% vs 18%; p < 0.001). Multivariate analysis revealed HCTZ as the only significant factor with a protective effect on occurrence of severe stage 2 AH. While monitoring safety and tolerability, mild asymptomatic hypokalemia was the only adverse effect observed more frequently in cohort 1 vs 2 (27% vs 3%; p = 0.013).

CONCLUSIONS

Targeting NCC by HCTZ significantly improved control of severe CNI-induced AH and was well tolerated in children who underwent LT. This effect may reduce the risk of long-term end-organ damage and improve quality of life.
Pediatric Sedation and Analgesia Outside the Operating Room: Combining Intranasal Fentanyl and Inhaled Nitrous Oxide
Authors: Hoeffe Julia , Vogel Regina G. , Ammann Roland A.
Published: July 2022

OBJECTIVE

Combining intranasal fentanyl (IN FENT) with inhaled nitrous oxide (N2O) seems to have good properties for pediatric procedural sedation and analgesia (PSA). This study aims to assess the side effect rate of the combined use of IN FENT and N2O.

METHODS

We performed a retrospective, single-center study. Patients treated in either the pediatric emergency department (PED) or the pediatric surgery outpatient clinic (PSOC) were included, if they received PSA with IN FENT and nitrous oxide with 50% oxygen (N2O 50%).

RESULTS

Three hundred seventy-five patients were included over a period of 4 years. Median age was 9.4 years (range, 3.1 to 15.9) and 39% of patients were female. Overall side effect rate was 30% (114 patients). Most frequent was dizziness (n = 63, 17%; 95% CI, 13–21), followed by nausea (n = 23, 6%; 95% CI, 4–9) and emesis (n = 14, 4%; 95% CI, 2–6), with 35 patients having either nausea and/or emesis (9%; 95% CI, 7–13). No serious side effects were recorded (0%; 95% CI, 0–0.1). Of 298 patients with information regarding satisfaction, 280 patients would like the same sedation for a similar procedure in the future (94%; 95% CI, 90–96). We found no relation between previously described risk factors and emesis and/or nausea.

CONCLUSIONS

N2O 50% combined with IN FENT can be recommended as an effective and safe treatment in the PED and the PSOC. While the side effect rate, primarily dizziness, nausea and emesis was substantial, antiemetic prophylaxis is not indicated owing to the overall low incidence of nausea and emesis.
Admission Medication Reconciliations in Pediatric Patients Admitted to an Inpatient Psychiatry Unit
Authors: Van Nguyen Anh , Romanowski Gale , Ley Michael , Lim Emily , McFarland Kaitlin , Morrison Tyler
Published: July 2022

OBJECTIVE

Medication errors resulting in adverse drug events may occur during transition of care. Most can be prevented with a medication reconciliation. California Senate Bill 1254 requires a pharmacist to perform an admission medication reconciliation (AMR) to obtain an accurate medication list for each high-risk patient upon hospital admission. Adult patient literature reveals that antidepressant, antipsychotic, and mood-stabilizing drugs are high-risk medications likely to cause errors. Therefore, the purpose of this analysis is to determine if pediatric psychiatry inpatients should be considered high risk, meriting an additional AMR by the pharmacy team.

METHODS

This was a retrospective, single-center analysis of pediatric patients admitted to the inpatient psychiatry unit at Rady Children's Hospital, San Diego between January 1 and 31, 2021. All newly admitted patients had an AMR performed by the medical team (physician-led AMR). High-risk patients (prescribed a high-risk medication or 3 or more medications of any kind prior to admission) had an additional AMR by the pharmacy team (pharmacy-led AMR). Differences between these 2 AMRs were examined.

RESULTS

Of the 58 patients admitted during the study period, 39 (67.2%) were identified as high risk, warranting an AMR by the pharmacy team. From the 170 medications reviewed, 51 differences (30%) were found between physician-led and pharmacy-led AMR, with 4 (2.4%) of the differences involving high-risk medications. No medications were incorrectly ordered, and no adverse drug events occurred.

CONCLUSIONS

Given that physician-led and pharmacy-led AMRs of high-risk prescription medications were only marginally different and no medications were incorrectly ordered, the existing AMR methodology used by psychiatrists at our institution is effective at creating a safe medication list.
Evaluation of Sirolimus Dosing in Neonates and Infants With Lymphatic Disorders: A Case Series
Authors: Serio Jordan , Gattoline Sarah , Collier Hailey , Bustin Anna
Published: July 2022

OBJECTIVE

Literature in pediatric patients suggests dosing sirolimus 1.6 mg/m2/day divided twice daily for lymphatic disorders with limited evidence available for dosing in neonates and infants. The objective of this research was to determine the sirolimus dose required to achieve therapeutic trough concentrations in infants with lymphatic disorders at Children's Hospital of Philadelphia.

METHODS

This retrospective review included patients <1 year of age at Children's Hospital of Philadelphia who were initiated on sirolimus for lymphatic disorder. Patients were included if they received at least 5 days of consecutive sirolimus therapy prior to trough concentration monitoring. Measures of central tendency and variability were used for statistical analysis.

RESULTS

A total of 16 patients met criteria for inclusion. The median initial sirolimus dose was 1 mg/m2/day (IQR, 0.5–1.6 mg/m2/day). Fourteen patients (87.5%) achieved therapeutic trough concentrations on a median sirolimus dose of 0.5 mg/m2/day. Dosing frequency to achieve therapeutic trough concentrations included 1 patient (6.25%) on twice daily dosing, 12 patients (75%) on once daily dosing, and 1 patient (6.25%) requiring every 48-hour dosing. The median time to first therapeutic trough was 15.5 days (IQR, 5.5–18.5 days), and patients required a median of 1 dose adjustment.

CONCLUSIONS

A median sirolimus dose to achieve therapeutic sirolimus trough concentrations in infants with lymphatic disorders was 0.5 mg/m2/day with a median of 1 dose adjustment. Sirolimus was well tolerated in the study population.
When There Is No Trough: Use and Outcomes of Continuous-Infusion Vancomycin at a Free-Standing Children's Hospital
Authors: Wysocki Emma , Tansmore Jessica
Published: July 2022

OBJECTIVE

There is minimal published literature regarding the use of continuous-infusion vancomycin (CIV) in children. The objective of this study was to describe the use, dosing requirements, and outcomes of CIV at a free-standing children's hospital.

METHODS

This is a retrospective review of patients who received CIV while admitted to Nationwide Children's Hospital between July 1, 2010, and June 30, 2020. The total daily dose (TDD) of vancomycin required to attain a target serum vancomycin concentration (SVC) was compared between CIV and intermittent-infusion vancomycin (IIV) administration regimens. Safety outcomes and treatment failure were also explored.

RESULTS

Fourteen patients (77% male) with a median age of 7 years (IQR = 1, 10 years) were included. Most patients (71%) were started on CIV in anticipation of outpatient parenteral antimicrobial therapy. The median TDD required to achieve a target SVC was higher with IIV compared with CIV (82.4 mg/kg/day vs 50.5 mg/kg/day; p = 0.02). Despite higher TDD with IIV, median SVC with IIV was similar to SVC with CIV (16.6 mg/L vs 17.6 mg/L; p = 2.00). There were no safety concerns or therapeutic failures identified with CIV.

CONCLUSIONS

Continuous-infusion vancomycin was a well-tolerated and effective alternative to IIV for the patients included in this study. The TDD of vancomycin required to achieve a target SVC was lower in patients receiving CIV compared with those receiving IIV.
A Survey from a Tertiary Care Hospital in India on Pediatric Medication Re-Dosing Practices After Patient Vomiting
Authors: Thangaraju Pugazhenthan , Natha Jondhale Sunil , Venkatesan Sajitha , Tanguturi Yella Sree Sudha
Published: July 2022

OBJECTIVE

The study was started in our institution to analyze the clinical problem and identify the benefits and drawbacks of current practices associated with drug re-dosing after vomitting. Opinions and perspectives from health care professionals from various pediatric hospitals were also gathered to build an effective and systematic protocol.

METHODS

Survey participants were recruited by using email distribution lists and forums catering to health care. Using this, 2 online surveys were carried out in the window period of 6 months.

RESULTS

Of the 14 responses from the study hospitals that were suitable for analysis, 64.2% reported pediatric patients that vomited after being administered oral medications: 7.1% faced this daily, 35.7% weekly, and 21.4% monthly. When respondents were asked to rate the importance of 8 factors potentially affecting the decision to re-dose, more than half indicated that the patient's vitals and condition (stable, unstable, or critical) were most important (57.4%), followed by time after ingestion (50%), familiarity with medication (42.8%), and formulation of medication (42.8%). Of 43 respondents from other institutions, only 11.9% had a functioning guideline for re-dosing in their institution.

CONCLUSIONS

Health care professional respondents to our surveys listed the time between ingestion and vomiting and the condition of the patient as the most important factors in their decision to re-dose the medication.
Rechallenge of Elexacaftor/Tezacaftor/Ivacaftor After Skin Rash in Two Pediatric Patients
Authors: Diseroad Emily R. , Mogayzel Peter J. , Pan Alice
Published: July 2022

Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have revolutionized care for patients with cystic fibrosis (CF). The triple combination product elexacaftor/tezacaftor/ivacaftor is a highly effective CFTR modulator that is generally well tolerated. However, in clinical trials of pediatric and adult patients, 4% to 12% developed rash after initiation of therapy. Few reports have described approaches to management of this adverse effect. In this report, we describe 2 children with CF who developed a pruritic, maculopapular rash after initiating elexacaftor/tezacaftor/ivacaftor. These patients were successfully rechallenged after rash resolution with a practical titration schedule.
Formação Continuada de Professores da Educação de Jovens e Adultos e Práxis Pedagógica: uma reflexão na perspectiva humanizadora e libertadora da educação
Authors: Oliveira Adriana Bastos , Silva Eduardo Jorge Lopes da , Alencar Maria Fernanda dos Santos
Published: July 2022

Este ensaio teórico de análise bibliográfica trata sobre a formação continuada de professores para a Educação de Jovens e Adultos (EJA).  Apresenta reflexões sobre a formação de professores e práxis pedagógica para os professores da EJA, numa perspectiva humanizadora e libertadora de educação. Neste sentido, constatou-se que: 1) a formação continuada de professores deveria ocorrer no próprio espaço da escola, balizada pelas realidades e tendo, por parte da academia e demais formadores, o reconhecimento dos saberes docentes num diálogo contínuo e formativo com aqueles que fazem a educação no chão das escolas 2) a formação continuada de professores, em destaque para o professor da EJA e a sua práxis pedagógica, deveria envolver a pesquisa/intervenção da/na realidade complexa do cotidiano escolar, com foco no compromisso político, nos valores éticos e morais favorecendo o desenvolvimento integral desse profissional da educação.
The global crisis is a crisis of civilization: a political ecology perspective
Authors: Toledo Víctor M.
Published: July 2022

Inspired by the intellectual currents of political ecology, this essay aims to shed light on the crisis of the contemporary world. The social sciences, or plain science, require a profound and urgent renewal in order to highlight the hegemonic structures of knowledge; Over-specialized studies, so common in recent decades, are barely capable of capturing fragments or pieces of reality, overlooking or ignoring the political power relations closely linked to the world they seek to study. It is clear that a radical transformation is required in all areas of social life and the first step is to accept that we are not facing a simple economic, technological or cultural change, but rather a transformation of human civilization.

Inspirado en las corrientes intelectuales de la ecología política, este ensayo pretende arrojar luz sobre la crisis del mundo contemporáneo. Las ciencias sociales, o la ciencia a secas, requieren una profunda y urgente renovación con el fin de poner de relie-ve las estructuras hegemónicas del conocimiento; los estudios sobreespecializados, tan comunes en las últimas décadas, apenas son capaces de capturar fragmentos o pedazos de la realidad pasando por alto o ignorando las relaciones de poder políticas estrecha-mente vinculadas con el mundo que pretenden estudiar. Es evidente que se requiere una transformación radical en todos los ámbitos de la vida social y el primer paso es aceptar que no estamos ante un simple cambio económico, tecnológico o cultural, sino ante una transformación de la civilización humana.
Maternal experiences of care following a stillbirth at Steve Biko Academic Hospital, Pretoria, South Africa
Authors: Jimoh A S , Wolvaardt J E , Adams S
Published: July 2022

Background. Despite improvements in obstetrics and neonatal care, the stillbirth rate remains high (23 per 1 000 births) in South Africa (SA). The occurrence of a stillbirth is a dramatic and often life-changing event for the family involved. The potential consequences include adverse effects on the health of the mother, strain on the relationship of the parents, and strain on the relationship between the parents and their other children. The standard of care in SA follows the Royal College of Obstetricians and Gynaecologists Green-top guidelines.Objectives. To explore maternal experiences of in-patient care received in cases of stillbirth.Methods. A descriptive phenomenological approach was performed in the obstetrics unit at Steve Biko Academic Hospital, Pretoria, SA. Post-discharge interviews were conducted with women who experienced a stillbirth. The healthcare workers in the obstetric unit were also interviewed on the care provided to these patients. Data analysis was performed using the Colaizzi’s method.Results. Data from the interviews with the 30 patients resulted in five themes relating to the maternal experience of stillbirth: ‘broken heart', ‘helping hand’, ‘searching brain’, ‘soul of service’ and ‘fractured system’. Healthcare worker participants emphasised the importance of medical care (the clinical guidelines) rather than maternal care (the psychosocial guidelines).Conclusion. While the medical aspects of the guidelines are adhered to, the psychosocial aspects are not. Consequently, the guidelines require adaptation, especially taking into consideration African cultural practices, and the inclusion of allocated responsibility regarding the application of the psychosocial guidelines, as this is the humanitarian umbilical cord between healthcare workers and those in their care.
Bleeding and thrombosis outcomes in hospitalised COVID-19 patients on low-molecular-weight heparin and antiplatelet therapy
Authors: Pillay-Fuentes Lorente V , Van Rensburg R , Moolla M S , McCaul M , Parker A , Taljaard J , Reuter H , Decloedt E H
Published: July 2022

Background. An increased incidence of thromboembolic events in hospitalised COVID‐19 patients has been demonstrated despite the use of low‐molecular‐weight heparin (LMWH). Antiplatelet therapy prior to admission and early in the disease course has been hypothesised to be protective against thrombosis.Objectives. To describe the bleeding and thrombosis outcomes in hospitalised patients with confirmed COVID‐19 receiving LMWH, with and without concomitant antiplatelet therapy. Secondary objectives were to explore predictors of bleeding and thrombosis outcomes, and dosing practices of antiplatelet therapy and LMWH.

Methods. We conducted a descriptive, cross‐sectional study of bleeding and thrombosis outcomes at Tygerberg Academic Hospital, Cape Town, South Africa, during the first COVID‐19 wave, in 808 hospitalised patients with confirmed COVID‐19 receiving LMWH with and without concomitant antiplatelet therapy. Multivariate logistic regression analysis was performed if predictors were deemed statistically and clinically significant.

Results. Patients receiving both LMWH and antiplatelet therapy had similar bleeding outcomes compared with patients only receiving LMWH (odds ratio (OR) 1.5; 95% confidence interval (CI) 0.6 ‐ 4.0). Patients receiving both LMWH and antiplatelet therapy had increased odds of developing thrombosis compared with patients only receiving LMWH (OR 4.8; 95% CI 2.1 ‐ 10.7).Conclusion. The bleeding risk in COVID‐19 patients receiving both LMWH and antiplatelet therapy was not significantly increased. A potentially higher risk of thrombosis in patients receiving LMWH and antiplatelet therapy was observed. However, this could reflect confounding by indication. Randomised studies are required to further evaluate the use of antiplatelet therapy to treat hospitalised patients with COVID‐19.
Right of reply
Authors: Matzopoulos Richard , Truen Sarah , Bowman Brett , Corrigall Joanne
Published: July 2022

-
Imágenes e inteligencia artificial: manos a la obra de nuevo
Authors:   Universitat Oberta de Catalunya, San Cornelio Gemma
Published: July 2022

Hace unos días aparecieron varias noticias relacionadas con la creación de imágenes con inteligencia artificial. Particularmente, se trata del software DALL-E y de su versión ligera DALL-E mini (que acaba de reconvertirse en Craiyon). Ambos son capaces de generar imágenes a partir de un texto. Curiosamente, coincidían con algunos eventos sobre arte digital, como el festival y congreso ISEA, celebrado recientemente en la ciudad de Barcelona.
NICOTINAMIDE-BASED IONIC LIQUID AS A POTENTIAL COPPER CORROSION INHIBITOR
Authors: Vaštag Đenđi , Apostolov Suzana , Vraneš Milan , Gadžurić Slobodan
Published: July 2022

In this paper, the possibility of using newly synthesized ionic liquid based on nicotinamide as a potential inhibitor of copper corrosion in an acidic sulfate medium was investigated. Inhibition efficiency of butyl-nicotinamide, [C4Nic]Br on copper corrosion in acidic (pH=3) 0.1 mol/dm3 sodium sulphate solution was analyzed using potentiostatic polarization measurements and electrochemical impedance spectroscopy (EIS). It was found that the investigated ionic liquid had inhibitory properties of the corrosion of copper in acidic media. The inhibitory effect of the test compound is manifested by rapid and spontaneous adsorption of [C4Nic]Br molecules on the copper surface following Langmuir’s adsorption isotherm. As a result, the cathodic corrosion current decreases, as well as the polarization resistance of the system, increases compared with the basic solution. The inhibition efficiency of the investigated compound largely depends on the applied concentration.
LOW-TEMPERATURE EQUILIBRATION REACTION AND PROPERTIES OF TELECHELIC SILOXANE OLIGOMERS
Authors: Balaban Milica , Bolka Silvester , Lorber Rebeka , Huskić Miroslav , Antić Vesna
Published: July 2022

Siloxane equilibration reaction in the presence of appropriate functional disiloxanes is a common method for the synthesis of telechelic siloxane oligomers. Due to the high reaction temperature, the synthesis of hydroxy-terminated polysiloxane is accompanied by several side reactions. In this paper, the synthesis of hydroxy-terminated siloxane oligomers at relatively low temperatures was optimized. The oligomers of the controlled molecular weight were synthesized in the presence of a heterogeneous catalyst and characterized by spectroscopic and thermal methods, as well as thermogravimetric analysis – infrared spectroscopy (TG-FTIR) and dilute solution viscometry.
THE IMPORTANCE OF THERMAL COMFORT OF THE URBAN ENVIRONMENT DURING SPATIAL PLANNING AND CONSTRUCTION
Authors: Đurić Dijana , Đurić Neđo , Stevović Svetlana
Published: July 2022

Urban areas in Bosnia and Herzegovina have been recording population growth. The city of Bijeljina has undergone major transformations in the appearance and purpose of the area due to the intensive construction process that is necessary to meet the needs of the increased population. The lack of greenery and the increased number of objects in a small area, as well as the intensified traffic, lead to discomfort among the population, which is manifested by many diseases related to thermal stress. There are many bioclimatic indices used to define the thermal comfort of an area. This paper will present the physiological subjective temperature (PST), which was analyzed for a period of 14 years (2005 - 2018) in the city of Bijeljina. Knowing the thermal comfort of an area before construction and before creating a spatial plan is important for reducing the number of people affected by heat stress and for providing guidelines for planning a more pleasant environment.
КОМПЕТЕНЦИЈЕ И МЕРИТОРНОСТ МЕДИОКРИТЕТА
Authors: Богојевић Светозар
Published: July 2022

Живимо у доба врхунца неолибералне демократије. То доба зачето је поодавно, с постмодерном као побуном против модерне, односно ра- ционалности и науке, окретом ка унутра, али тај окрет показао се не- искреним, јер за искрено истинит окрет ка унутра није довољно обе- збедити субјективитет индивидуе заснован на спољашњој, институ- ционално организованој друштвеној сигурности. За искрено истинит субјективитет неопходно је духовно напрезање свих индивидуа при усаглашавању око друштвености. Али духовног напрезања и усаглаша- вања нема без духовног трпљења. Дакле, проблем и није у нарастању рационалности, већ у недостатку њој комплементарне ирационално- сти садржане у неопходној спремности сваке поједине индивидуе на трпљење при усаглашавању. Патња, схваћено људски, јесте самоужи- так човека (Маркс). Уколико трпљење и патња изостају, нема израс- тања индивидуе у личност. Окрет ка унутра показао се претешким. Учинило нам се да је проблему људскости много лакше приступити рационално, уз пермисивно посредство институција. Али ако нема до- вољног броја, непосредованим духовним трпљењем, из себе израслих, одговорних личности долази до посрнућа демократије и декаденције друштва, па упркос тежњи меритократији, осмишљеној кроз уређење друштва помоћу институција, доспевамо до мериторности медиокри- тета – мериторности просечности. Неолиберална демократија тиме се разоткрива као привид демократије – медиокритетска демокра- тија, а њом произведена друштвеност као привид слободе. Како до тога долази?
ПОИМАЊА ИМПЛИЦИТНОГ ВАСПИТАЊА У УМЈЕТНОСТИ И КУЛТУРИ
Authors: Јовић Слободан
Published: July 2022

Циљ овог рада јесте анализа текстова о имплицитном васпитању у областима културе и умјетности, као и указивање на интересовања за проблематику васпитања и у ваншколским областима. У раду је примијењена метода теоријске анализе и синтезе, а анализирани су доступни радови који су се бавили проблемом имплицитног васпитања. Својим проучавањем утврдили смо да се радови о имплицитном васпи- тању могу сврстати у оне који се баве: а) имплицитним васпитањем у поетским текстовима, б) имплицитним васпитањем у традиционал- ној и медијској култури, в) имплицитним васпитањем у есејистичким текстовима, г) имплицитним васпитањем у уџбеницима. На основу увида у публиковане радове, закључили смо да култура и умјетност, саобразно језику и медију којим саопштавају поруке, интензивирају занимање за проблематику васпитања. Такође, закључили смо да су најбројнији радови који за предмет проучавања имају народне, тра- диционалне погледе на дијете, дјетињство и васпитање, што указује на то да традиционални погледи на васпитање и дјетињство имају значајну улогу у обликовању васпитних стратегија.
ПРОЦЕНЕ ВАСПИТАЧА О КОРЕЛАЦИЈИ АКТИВНОСТИ У ВАСПИТНО-ОБРАЗОВНОМ РАДУ СА ПРЕДШКОЛСКОМ ДЕЦОМ
Authors: Миловановић Бошко , Драгић Желимир
Published: July 2022

Концепт корелације активности пожељан је у раду са децом у предшколским установама, јер деца на тај начин могу лакше да уче и да повезују претходно стечено искуство са новим искуствима. Како бисмо указали на значај корелације активности у раду са децом предшколског узраста, спровели смо емпиријско истраживање са ва- спитачима предшколске деце. Интересовало нас је у којој мери вас- питачи користе корелацију активности у вртићу, када је најчешће примењују и да ли при таквом приступу користе средства информа- ционе технологије. Циљ истраживања био је да се испитају процене васпитача о могућностима и значају примене корелације активности у раду са децом обухваћеном институционалним предшколским вас- питањем. У истраживању је кориштен анкетни упитник, а добијени истраживачки налази указују на то да васпитачи свој рад углавном базирају на корелацији активности (али наводе и да је за њену реализа- цију потребно много више времена). Резултати истраживања указају на то да васпитачи у свом професионалном ангажовању и спровођењу корелације активности у вртићу све више користе информациону технологију.
ДИЈАЛЕКТИКА И ИНТУИЦИЈА У ДОБА ВИРТУЕЛНЕ РЕАЛНОСТИ
Authors: Павловић Златко
Published: July 2022

Када професори педагогије студентима говоре о тој науци, објасне им да је она, као и друге науке, настајала у оквиру филозофије, а кас- није им предоче педагошке идеје неких важнијих филозофа и помену утицај филозофских праваца на педагошке правце и концепције. По- што се одради та обавеза помињања везе педагогије са филозофијом, прелази се на другачије теме, које се тичу научне објективности, мето- да истраживања, хипотеза, варијабли, мјерења, обраде података, логич- ког извођења закључака итд. Зато ми о односима филозофије и педаго- гије често формирамо представу као о нечему узгредном и архаичном. Срећом, увијек су постојали (ма како да их је некад било мало) и они педагози који су нас својим дјелима подсјећали да је веза педагогије са филозофијом исконска и зато нужно жива, који су одржавали пламен те везе. Један од таквих педагога је и Светозар Богојевић. Више је дјела којима је он испуњавао ту своју мисију. Једно од њих је и посљедња његова књига Дијалектика и интуиција у доба виртуелне реалности.
Burocracias humanitarias en Colombia: conocimiento técnico y disputas políticas en la implementación de la Ley de Víctimas y Restitución de Tierras
Authors: Vera Lugo Juan Pablo
Published: July 2022

Through an ethnographic study of the policy of reparation to victims in Colombia, this article examines the processes of the production of expert knowledge along different scales and disputes of humanitarian bureaucracies in Colombia. These emerge from the institutional deployment of development and peacebuilding paradigms, at least since 1982, with the creation of the National Rehabilitation Plan (PNR), the Social Solidarity Network (RSS) in 1994, the Presidential Agency for Social Action and International Cooperation in 2002, and the Department of Social Prosperity (DPS) in 2011. With the subjugation of some paramilitary groups in 2006 (Justice and Peace Law), the Victims and Land Restitution Law in 2011, and the peace agreements with the Revolutionary Armed Forces of Colombia - People’s Army (FARC-EP) guerrillas in 2016, transitional institutions associated with truth, justice, and reparation proliferated, and with them, specific bureaucracies and expertise. Thus, the article specifically examines the technical and political tensions between different professional and ideological configurations associated with the implementation of reparations policy and how these disputes are essential to understanding the moral and ideological dimensions of humanitarianism and development in Colombia. It also studies the role of cooperation agencies in inter-institutional strengthening as a specific dimension of the formation of the Colombian State. These articulations configure a moral economy of humanitarianism characterized by institutional experimentalism and the formulation of social projects, expectations, plans, and ideas that never reach the status of having been realized. This strips such policies of any transformative or emancipatory potential. Thus, from an ethnographic perspective, the article provides an account of the techno-political tensions of humanitarian bureaucracies at the middle scales of regional, national, and global institutional structures.
Enseñar un pasado controvertido desde un presente polarizado: la memoria histórica en España desde la perspectiva docente
Authors: Martínez-Rodríguez Rosendo , Sánchez-Agustí María , Muñoz-Labraña Carlos
Published: July 2022

In societies with divided and contradictory memories of their recent past, the resulting historical memory is heavily conditioned by a process of cultural, public, and mediatized construction that hinders a proper educational treatment of recent history and memory in the classroom. This is the case of Spain, where, after a long dictatorship (1939-1975), an agreed transition to democracy and the memory of the civil war (1936-1939), continue to give rise to conflicting narratives, strongly connected to present interests. In this study, we focus on the conceptions and opinions of a group of 39 teachers from seven Spanish cities and historical territories. They have been interviewed in order to learn about their experiences and to analyze their conceptions regarding historical memory and its public management in Spain. Teachers’ perceptions are relevant because they are representative of an educated population, with historical training, but above all because they play a fundamental role in the construction or transmission of memories from the educational sphere. The results reveal a deep divide around historical memory and its recovery in the Spanish context. Despite the time that has passed, history professors do not hesitate in recognizing today the social fracture of the civil war and Franco’s regime, which they connect with current ideologies and political discourses. At educational level, these events are treated from an equidistant and equalizing perspective in order to avoid conflict and problematized interpretation in favor of a superficial and pacifying vision. The results suggest that certain collective memories of societies in conflict persist over time, and that it is the polarization of the present that encourages a mythologized reading of the past.
An empirical Bayes approach to stochastic blockmodels and graphons: shrinkage estimation and model selection
Authors: Peng Zhanhao , Zhou Qing
Published: July 2022

The graphon (W-graph), including the stochastic block model as a special case, has been widely used in modeling and analyzing network data. Estimation of the graphon function has gained a lot of recent research interests. Most existing works focus on inference in the latent space of the model, while adopting simple maximum likelihood or Bayesian estimates for the graphon or connectivity parameters given the identified latent variables. In this work, we propose a hierarchical model and develop a novel empirical Bayes estimate of the connectivity matrix of a stochastic block model to approximate the graphon function. Based on our hierarchical model, we further introduce a new model selection criterion for choosing the number of communities. Numerical results on extensive simulations and two well-annotated social networks demonstrate the superiority of our approach in terms of parameter estimation and model selection.
Marker-assisted pyramiding of γ-tocopherol methyltransferase and glutamate formiminotransferase genes for development of biofortified sweet corn hybrids
Authors: Lv Guihua , Chen Xiaolong , Ying Duo , Li Jiansheng , Fan Yinghu , Wang Bin , Fang Ruiqiu
Published: July 2022

Micronutrients, including vitamins, minerals, and other bioactive compounds, have tremendous impacts on human health. Much progress has been made in improving the micronutrient content of inbred lines in various crops through biofortified breeding. However, biofortified breeding still falls short for the rapid generation of high-yielding hybrids rich in multiple micronutrients. Here, we bred multi-biofortified sweet corn hybrids efficiently through marker-assisted selection. Screening by molecular markers for vitamin E and folic acid, we obtained 15 inbred lines carrying favorable alleles (six for vitamin E, nine for folic acid, and three for both). Multiple biofortified corn hybrids were developed through crossing and genetic diversity analysis.