bluuebunny/crossref_metadata_2025 huggingface dataset:
Study of immuno-histochemical markers ER, PR and Her2/neu in ovarian neoplasms
Authors: Choudhary Anjana , Pachori Geeta , Mavaliya Vivek , Pachori Saroj
Published: May 2022

Background: Among genital malignancies, ovarian cancer has the most increased mortality rate. ER, PR and HER2/neu expression levels depend on tumour histologic grade, stage of disease and age group. Aim of the study was to study the clinic-pathological parameters in ovarian tumours with reference to age, histologic type and grade and their correlation with ER, PR and HER2/neu status.Methods: The prospective study of 2 ½ years was conducted on 100 resected ovarian tumour specimens from June 2017 to December 2019 received in the department of pathology, JLN medical college, Ajmer. Sections were examined for presence of ovarian tumour, histological type, grade and for ER, PR and HER2/neu status, immunohistochemistry was done.Results: Out of 100 cases, 72 cases were benign, 03 cases were border-line and 25 cases were malignant. Serous tumors were most common among all epithelial tumors (61%). Malignant cases showed maximum positivity with ER, PR and HER2 as 61.76%, 68% and 100% respectively. ER, PR and HER2/neu positivity in serous epithelial tumors was 76.47%,84% and 90% and in mucinous tumors was 20.59%, 12% and 10% respectively. Majority of positive ER, PR and HER2/neu receptors was observed in age groups of >40 years as 64.71%, 64% and 85% respectively. ER, PR and HER2/neu positivity seen in higher grade and stage tumors as 76.19%, 76.47% and 70% in grade 3 and stage 3 tumors respectively.Conclusions: The higher expression of ER, PR and HER-2/Neu is associated with progression of invasive cancer, higher grade and stage of ovarian tumors, higher age group, and multiparty.
Evaluation of effective anti-tumarogenic dose of ethanolic leaves extract of Moringa oleifera Lam. in Ehrlich ascites carcinoma bearing mice
Authors: B. Ramanath , John Abhay
Published: May 2022

Background: To evaluate the optimum protective and curative antitumarogenic dose of the ethanolic leaves extract of Moringa oleifera Lam (ELMO). variety against Ehrlich ascetic carcinoma (EAC) cells.Methods: The protective and curative antitumor activity of ELMO was evaluated against the EAC tumor model. The activity was assessed using survival time and increase in life span.Results: Oral administration of all the doses of treated ELMO shown significantly increased in mean survival time and percent of life span, in that 500 mg/kg body wt. shown highest significance.Conclusions: ELMO treated 500 mg/kg body wt. possesses showed antitumor activity.
Observational study to characterize socio-demographic data and clinical presentation in patients with acute exacerbation of chronic obstructive pulmonary disease
Authors: Sharma Amit , Bhardwaj Mamta , Jain Prerna , Tayal Devika
Published: May 2022

Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease with high global morbidity and mortality. It is characterized by poorly reversible airway obstruction. The major risk factor associated is smoke exposure which leads to chronic respiratory failure. Various chronic medical conditions commonly coexisting with COPD include coronary artery disease, diabetes mellitus, osteoporosis and muscle weakness. Co-morbid conditions should be managed appropriately along with treatment of COPD. Present observational study was undertaken to characterize socio-demographic data, clinical presentation and possible co-morbidities (cardiac, diabetes mellitus, and hypertension) in COPD patients. The observed data was analyzed to study prevalence of all parameters gender wise and relation with diagnostic technique i.e. chest X-ray and electrocardiography (ECG) for cardiac screening. Therefore, in the following study, elderly and male patients were prominently affected by COPD with common symptoms of cough, breathlessness, expectoration, fever and chest pain. Diabetes is one of the co-morbidities observed in this set of patients. Hence, random blood sugar (RBS) and glycated hemoglobin (HbA1c) parameters were deranged in this cohort of patients. Additionally, ECG was also observed to be abnormal in few patients. Conclusively, this study highlighted various demographic features, clinical symptoms and comorbidities responsible for health burden of COPD patients.
COVID-19 pneumonia and mucormycosis a new challenging duo- rhino-occulo-cerebral mucormycosis: a case report
Authors: Atri Sudhir K. , Fotedar Sanjay , . Homdutt , Malik Vinay , Punia Parul
Published: May 2022

The pandemic of corona virus disease 2019 (COVID-19) has posed challenge not only in management of the primary disease but the emerging complications associated with COVID-19 has further complicated the course of disease. The course of COVID-19 disease is associated with infectious and noninfectious complications former include secondary bacterial and fungal infection adding to mortality and morbidity. COVID-19 disease associated candidiasis and aspergillosis have been reported as super infections but with the steroid and supplemental oxygen as mainstay treatment modality mucormycosis is now complicating the course of disease and presently posing challenge in India with already overburdened health care service. Mucorales is a saphrophytic fungi causes rhinocerebral infection involving nasal passages, sinuses, oral cavity and brain. It is usually seen in immunocompromised host and in diabetics with poorly controlled blood sugar level. High degree of clinical suspicion is needed to suspect and diagnose mucormycosis. It is a fatal disease because of its angioinvasive pathogenesis and treatment is promptly initiated to salvage mortality and morbidity. Authors report a case of rhino-oculo-cerebral mucormycosis in a middle-aged diabetic patient with severe COVID-19 disease.
Paroxysmal exercise induced dyskinesia and writer’s cramps in twin siblings with SLC2A1 mutation
Authors: Banotra Pankaj , Bharti Anamika , Wangnoo Areca
Published: May 2022

Paroxysmal exercise induced dyskinesias (PED) are rare disorders with recurring episodes of sudden involuntary movement disorders precipitated by physical exercise. It had been reported that less than 20% of PED patients carry an SLC2A1 mutation encoding GLUT 1 of whom 49 patients have been identified worldwide We hereby reported a case of twin siblings, 23 year old male with no antecedent other past illness and family history presenting with writer’s cramps and paroxysmal exercise induced dyskinesia attributed to milder phenotype of glucose transporter type 1 deficiency with the heterozygous exon-6 SLC2A1 gene mutation. Ketogenic diet in these patients may help in these cases.
Management of chronic constipation in comorbid conditions
Authors: Bagepally Ravi Shankar
Published: May 2022

Constipation is a common clinical problem in India. It is also a secondary condition in many disorders. This article focused on clinical assessment and evidence-based treatment options for managing chronic constipation in various disorders. A literature search of published medical reports in the English language was performed using PubMed from inception to 2021. The selected articles satisfied the following inclusion criteria: involved human subjects over the age of 18 years and reported at least one of the comorbidities among hypothyroidism, diabetes and hypertension along with chronic constipation. Chronic constipation is one of the most common gastrointestinal symptoms observed in patients with diabetes, hypertension or hyperthyroidism. Constipation in diabetic patients can occur due to several factors such as autonomic dysfunction, dietary habits and medications. The change in the intestinal microbiota because of chronic constipation can also induce cardiovascular events. The association between these changes and increased blood pressure in hypertension had been discussed in this review. Additionally, the link between disturbed gastrointestinal motility and chronic constipation leading to hypothyroidism had also been explored. Furthermore, the pharmacological and non-pharmacological management of chronic constipation in patients with diabetes, hypertension, and hypothyroidism have been discussed. Emphasis has been placed on the changes required in the existing treatment options for diabetes, hypertension and hypothyroidism along with the use of laxatives, dietary fibers, bulking agents, lifestyle changes and other interventions to manage chronic comorbid constipation.
Effects of behavioural change communication on HIV and AIDS related high risk behaviour among fishermen in Homabay and Siaya Counties, Kenya
Authors: Akobi William Kala , Oyore John Paul , Otieno George Ochieng
Published: May 2022

Background: Risky sexual behaviors such as sexual concurrency, sexual networks (fish for sex exchange) and unprotected sex, have been reported as the main cause of sexually transmitted diseases (STIs) /HIV infections among fisher folks. Behavioral change mechanisms as condom use and abstinence are some of interventions used in prevention HIV/AIDS spread in Kenya. Risky sexual behaviors increase risk of contracting STIs including HIV/AIDSMethods: This was a cross-sectional descriptive study involving 246 randomly selected fisher folks in Mbita- and Usenge along Lake Victoria. The survey used questionnaires to collect data among respondents. Using a sample frame in the beach management unit offices, fisherfolks were identified and invited to participate. Consent was obtained from participantsResults: The mean age of respondents was 31 years old. The 72% of the participants were directly involved in fishing. Participants who had extra marital relationship though married were 56.1% in Mbita and 47% in Usenge. Respondents who took alcohol with friends were 94.1% in Mbita and 96.2% in Usenge. Respondents who indicated that they had unprotected sex under influence of alcohol were 48.3% in Mbita and 77.1% in Usenge. Those who were sexually taken advantage of while under the influence of alcohol were 23.8% in Mbita and 38.3% in Usenge while those had sexually taken advantage of under the influence of alcohol were 18.3% in Mbita and 37.8% in Usenge.Conclusions: Targeted behaviour change communication (BCC) strategies designed specifically for fisherfolks is needed to curb high incidences of risky sexual behaviours noted among the fishermen.
Perceptions of third year degree nursing students at University of Namibia, regarding the causes of infant mortality rate in Windhoek, Havanna informal settlement, Namibia
Authors: Akafingo Johanna , Amakali-Nauiseb Taimi , Nashandi Hilde L.
Published: May 2022

Background: The purpose of the study was to determine the knowledge and attitude of 3rd year degree nursing students at UNAM regarding the causes of infant mortality rate in Windhoek, Havana settlement, Namibia.Methods: A cross sectional descriptive study was conducted on the 3rd year nursing students at UNAM. A sample size of fifty students was used. Questionnaires were used to obtain data; data collected included socio-demographic data, questions on knowledge and attitudes. The data obtained was analyzed using descriptive analysis and presented using narration, tables, pie charts and bar graphs.Results: A response rate of 100% was achieved. The majority of the participants were female 94% and 6% were male, with grade 12 certificates as highest level of qualifications. Overall participants had good knowledge on the causes of infant mortality in the Havana informal settlement, Windhoek Namibia.Conclusions: Participants displayed good knowledge and attitude regarding the causes of infant mortality rate in Havana informal settlement, Windhoek Namibia.
Risk factors associated with depression among HIV positive women at Mama Lucy Kibaki hospital in Nairobi County, Kenya
Authors: Jeruto Esleen , Mogere Dominic M. , Kerochi Atei , Maureen Koech J. , Gwandi Martin P.
Published: May 2022

Background: Globally, 280 million people are estimated to have depression. Depression has been associated with negative treatment outcomes and reduced quality of life. The study aimed to determine the prevalence and correlates of depression among HIV-positive women at Mama Lucy Kibaki hospital in Kenya.Methods: A facility-based cross-sectional analytical study design that employed a mixed-method approach. The study employed systematic random sampling to select 183 HIV-positive women. The patient health questionnaire (PHQ-9) was used to screen for depression. Data analysis used statistical package for social sciences. Chi-square test and logistic regression were used to test and measure association.Results: The prevalence of possible depression was 35.6%. Depression was significantly associated with food insecurity (AOR=8.186, C.I=2.950-22.718), low income (AOR=3.766, CI=1.088-13.030), physical exercise (AOR=64, CI=0.039-0.627), maladaptive coping style (AOR=9.585, CI=3.100-29.634), stressful life event (AOR=47, CI=0.005-0.088), intimate partner violence (AOR=36, CI=0.086-0.857), opportunistic infections (AOR=5.8, CI=0.081-0.366) and side effects of antiretroviral (AOR=7.6, CI=0.029-0.601). Themes from qualitative findings were; low socioeconomic status, stigma and opportunistic infectionsConclusions: The study revealed a high prevalence of depression but they were more likely to be depressed if they were food insecure, had low income, adopted maladaptive coping styles, experienced a stressful event, intimate partner violence, had opportunistic infections and experienced side effects of antiretroviral. Future mental health interventions should focus on these factors in the prevention and management of depression among HIV-positive women.
Barriers to mental health services utilization among outpatient clinic attendees at Mathari National teaching and referral hospital, Nairobi City, Kenya
Authors: Victor Chelelgo Kibichii , Gilbert Munyoki Muima , Ondora Onyambu Meshack , Abel Khisa Otieno
Published: May 2022

Background: World health organization defines mental health as a state where people realize and recognize their capacities, cope with life stressors, and contribute positively to the society. A gap exists between the need or demand for mental health services and their utilization due to a set of barriers that limit access. The prevalence of mental illnesses is approximately 10%. The study sought to investigate barriers to utilization of mental health services.Methods: The study used mixed-method research approach that is cross-sectional descriptive and qualitative study design. The study was conducted at Mathari national teaching and referral hospital outpatient clinic. Structured questionnaires and key informant interviews were used to collect data. Study participants comprised 216 caregivers of mentally ill patients and 6 key informants.Results: Costs of seeking mental health services is a barrier to accessing these services at the MNTRH outpatient clinic. More than half of the participants missed their clinics due to cost of medication, 56% (n=120), consultation costs 55% (n=118), and transport=54% (n=116). Caregivers sought other types of mental health services such as spiritual healing before taking their mentally ill relative for formal care. People with mental illness experienced social stigma 59.3% (n=128).Conclusions: The cost of mental health service access and stigma are the outstanding barriers to access and utilization of mental health services.
Synergistic effect of inthrathecal fentanyl and bupivacaine in spinal anesthesia for cesarean section in Baghdad city
Authors: Habasha Zainab Faisal
Published: May 2022

Background: Potentiating the effect of intrathecal local anesthetics drugs by addition of intrathecal opiods for intra-abdominal surgeries had been used lately. In this study by addition of fentanyl, we tried to minimize the dose of bupivacaine thereby reducing the side effect caused by higher doses of intrathecal bupivacaine in cesarean section, and to improve the quality of block.Methods: Study was performed on sixty patients underwent cesarean section they were divided into 6 groups as B10, B 12.5, B15 mg of bupivacaine and FB10, FB12.5, FB15 received a combination of 25 µg intrathecal fentanyl respectively, the parameter taken into consideration were visceral pain, hemodynamic stability (hypotension and bradycardia) intra operative sedation, nausea, vomiting and post-operative pain. Results: Onset of sensory block to T6 occurred faster with increasing bupivacaine doses in bupivacaine only groups and bupivacaine fentanyl combination groups. Alone lower concentration of bupivacaine could not completely remove the visceral pain. Blood pressure declined with increasing the concentration of bupivacaine and fentanyl. The incidence of nausea and vomiting was reduced significantly while post-operative pain relief and hemodynamics stability increased by adding fentanyl. Pruritis, maternal respiratory depression and changes in APGAR score of babies did not occur with fentanyl. Conclusions: Spinal anesthesia among the neuro axial blocks in obstetric patients’ needs strict dose calculation because minimal dose changes results in more complications and side effects Here the synergistics potentiating effects of fentanyl (an opiod) on bupivicaine (local anesthetic) in spinal anesthesia for cesarean section is presented. Fentanyl is able to reduce a dose of bupivicaine and therefore its harmful effect.
Assessment of the knowledge, attitude and practice towards palliative care amongst the 4th year nursing degree students at Windhoek Campus, University of Namibia
Authors: Shigwedha Nive N. , Amakali-Nauiseb Taimi , Runone Kalista
Published: May 2022

Background: Nursing students who will be future nurses should have adequate palliative care knowledge, positive attitude and good practices. In Namibia, the nursing students’ knowledge, attitude and practice regarding palliative care remain unknown. This study was aimed at assessing the knowledge, attitude and practices towards palliative care amongst the 4th year nursing degree students at Windhoek Campus, University of Namibia.Methods: A cross-sectional survey using a quantitative approach with self-administered questionnaire as a tool for data collection was utilised among 83 nursing degree students. A simple random sampling technique was used in selecting the participants and a response rate of 98.7% (n=82) was achieved.Results: Showed the following: knowledge towards palliative care is suboptimal as only 54.9% (45) participant had good knowledge towards palliative care, while 45.1% (37) participants had poor knowledge on palliative care. Practice towards palliative care was good as 91.5% (75) participants had good practice towards palliative care, whilst 8.5% (7) participants bad practice. The overall level of attitude shows positive attitude amongst participants as 76.8% (63) had positive attitude towards palliative care, while 23.2% (19) had negative attitude.Conclusions: Integrating palliative care education is required as a pillar to improve student’s knowledge where the nursing educators are not only designing proper teaching content but also, they are using various teaching strategies to promote active and experimental learning regarding palliative care.
A study on the clinical spectrum, prescription pattern and diagnosis of enteric fever in a tertiary care hospital of North India
Authors: Chatterji Soumyadip , Sharma Priyanka , Kaur Avinash , Kalyanasundaram Dinesh , Biswas Ashutosh , Wig Naveet , Kapil Arti
Published: May 2022

Background: Enteric fever is a major public health concern in developing countries. Lack of diagnostics diagnosis and antimicrobial resistance challenges in treatment of enteric fever. Timely diagnosis and proper management of fever are essential to reduce the complications and emergence antibiotic resistance.Methods: A prospective observational study was conducted on 71 subjects between February 2018 and December 2019. Spectrum of the disease, antimicrobial resistance and prescription pattern were observed and performances of various diagnostic methods (like culture, serology and loop mediated isothermal amplification) were determined.Results: The most commonly observed clinical features included gastrointestinal complaints, anaemia, leukopenia, splenomegaly and hepatitis. Blood culture was positive for 49.3% (35/71) of the cases using conventional culture method. All samples positive by LAMP were also culture positive, out of which 80% (28/35) were S. typhi and 20% (7/35) were S. paratyphi A. Antimicrobial susceptibility to ciprofloxacin was 39.3% and 28.6% and ampicillin susceptibility was 32.1 and 28.6% in S. typhi and S. paratyphi A respectively. Only one multidrug resistant isolate was noted, while none was resistant to ceftriaxone or azithromycin. Cefixime and azithromycin combination therapy led to the earliest defervescence of fever.Conclusions: Oral combination therapy may be a good option to treat enteric fever and oral combination therapy may be a good option to treat enteric fever and performance of LAMP seem to be as good as culture with a shorter turnaround time. LAMP can be used to obviate the need of culture in resource limited settings.
A methodological study to determine emotional and behavioural problems with associated factors among children of institutional homes in Raipur, Chhattisgarh
Authors: Agrawal Akshat , Sinha Ashish , Gupta Shubhangi , Kotwani Pranshul
Published: May 2022

Background: Children residing in institutional homes are more susceptible to behavioural and emotional problems in comparing to other children in the same age group. It has been discovered that when developmental processes inside the institution are accelerated over time, they can result in restricted cognitive activity and cultural expression patterns. Unresolved negative emotions, such as anger and depression, put children at danger of growing up with harmful emotions.Methods: To study the children's behavioural and emotional problems, in the present study, the sample of 142 people who lived in Raipur's institutional homes were considered. A semi-structured questionnaire was used to obtain sociodemographic information. The behavioural and emotional difficulties in them were assessed using the strengths and difficulties questionnaire (SDQ) with impact supplement. The sex of the children, satisfaction with the food provided, caretaker behaviour, years of stay, and reasons for being at the institution were not shown to be substantially associated with emotional and behavioural difficulties in children in our study.Results: Based on the SDQ, 52.1% children and adolescents in the present study had scores greater than the cut-off score of 28, indicating that those with SDQ scores greater than 28 had some social and behavioural problems, and hence are marked positive for emotional and behavioural problems. The age of the participants was found to be a strong predictor of emotional and behavioural issues.Conclusions: The majority of the subjects were pleased with their caretakers' behaviour, the quality of the water supply, and the sanitary facilities, implying favourable environmental conditions.
Long COVID-19 and achalasia: a possible relationship?
Authors: Aponte Raúl , Daulabani Nefertiti , Parra Rosargelis , Pérez-Ybarra Luis
Published: May 2022

Achalasia is a rare esophageal motor disorder with a worldwide prevalence of around 10 cases per 100 000 inhabitants, and an incidence of one new case per 100 000 inhabitants per year. It is characterized by loss or decrease of myenteric plexus neurons in the distal esophagus and lower esophageal sphincter, presenting dysphagia and regurgitation. The objective of this work was to show that the presence of type II achalasia could be a sequela of the COVID-19 infection. Patient histories were reviewed during the 2015-2021 period, the frequencies of achalasia with and without COVID-19 were calculated. Patient profiles were constructed by using cluster analysis based on clinical variables. It was found that frequency of patients with achalasia during the years 2020 and 2021 was higher than that observed in previous years, and by the year 2021, 2/3 of the patients with achalasia had presented COVID-19 infection, in addition, the patients with type I achalasia presented different profiles than patients with type II achalasia according to the cluster analysis, and the frequency of COVID-19 was much lower in patients with type I achalasia. These results seem to indicate type II achalasia could be a sequela of COVID-19 infection. The possible etiopathogenic implications of these results are discussed, as well as their clinical relevance.
Prevalence of mismatch repair mutations in colorectal carcinoma patients in Mangalore
Authors: Nair Vineeth G , Shariff M H
Published: May 2022

Colorectal cancer (CRC) is highly prevalent throughout the world and represents the 3rd most common cancer in men and the 2nd in women worldwide. Microsatellite instability (MSI) is a term used to denote a hypermutable phenotype caused by the loss of DNA mismatch repair (MMR) activity, and is a phenomenon now linked to the pathways of colorectal carcinogenesis. Compounding its importance is its integral association with Lynch syndrome, the most common cause for CRCs in young individuals. In the present study, we aimed to analyse the proportion of patients with risk of microsatellite instability by checking for loss of immunostaining for mismatch repair (MMR) proteins.

From January 2016 to December 2016 and May 2017 to October 2017, 40 consecutive newly diagnosed cases of colorectal cancer were included in the study. The expression of MMR proteins in the tumour tissue using IHC for MSH2, MSH6, MLH1 and PMS2 was studied.

Among the 40 cases, 3 (7.5%) demonstrated loss of MMR proteins and 37 (92.5%) cases had intact nuclear expression. Out of the three cases with MMR loss, one showed concurrent loss of MLH1 and PMS2, the second showed concurrent loss of MSH2 and MSH6 and the third showed an isolated loss of MSH6.

Colorectal carcinomas showing MMR mutations are seen in the Mangalorean population. However, the incidence in our study was relatively low compared to most other studies, probably due to a variation in ethnicity.
Benign collision tumour of the parotid gland – A rare case report
Authors: Mani Suresh , Anto Ronald , Baitule Amey , Michael Rajiv C
Published: May 2022

Diagnostic pathology in parotid gland (PG) is extremely versatile, due to the diversity, aetiology and histogenesis of PG tumors. Synchronous tumors (either hybrid or collision) are described as two or more distinct neoplasms arising in the same anatomical location, either malignant or benign. We present a case of parotid swelling diagnosed to be Warthin’s tumor (WT) preoperatively which turned out to be a Pleomorphic adenoma – Warthin’s collision tumor. This rare type of collision tumor, was managed successfully by surgery with close follow-up. We aim to enlighten surgeons and pathologists about this rare condition to make them familiar about the difficulties in diagnosis and management of the tumor.
Papillary thyroid carcinoma of the Warthin like type, a rare variant: A case report
Authors: Akioud Fatima , Abainou Lhoussaine , El-hadri Sanaa , Idrissi Ayoub , Belaabidia Badia , Azami Amine , Meftah Azzelarab , Baizri Hicham
Published: May 2022

The Warthin-like variant is a rare and relatively unknown entity of papillary thyroid carcinoma. It is frequently associated with Hashimoto's thyroiditis. The cytologic diagnosis is difficult to evaluate because of the overlap of its findings with the classic variant and Hashimoto's thyroiditis. However, this variant has unique morphologic features that make it easily recognizable on histologic examination. These tumors have a resemblance to Warthin's tumor of salivary gland origin.

The few case series reported in the literature have suggested that the mean age, sex distribution, circumstances of discovery, and prognosis are the same as those reported for classic papillary thyroid carcinoma.

We report here a case of Warthin like variant papillary thyroid carcinoma in a 42-year-old female patient followed for Hashimoto's thyroiditis.
A rare entity-lateral inflammatory follicular cyst
Authors: Aijaz Adma , Tyagi Nutan , Kaur Geetpriya
Published: May 2022

Sometimes, there is failure in tooth eruption not because of any physical barrier or abnormal position. The reason for the failure of tooth eruption in this current case is due to uncommon phenomenon. There was a swelling in the lower canine region bilaterally with impacted the 32,33,42 and 43. This case also shares a detailed CBCT report and microscopic features of the rare entity, the lateral inflammatory follicular cyst.
Ovarian sclerosing stromal tumour in a 39-year-old lady- A case report and review of the literature
Authors: Thomas Alina Ajoy , Thomas Meeta , Mathews Rebecca , Pothen Lillykutty
Published: May 2022

One of the rarest ovarian sex cord-stromal tumour is Sclerosing Stromal Tumour (SST). It commonly presents as lower abdominal pain and tenderness, with or without a mass, and/or abnormal menses. As the clinical presentation and imaging are like borderline or malignant epithelial tumours and sex cord-stromal tumours, accurate preoperative clinical diagnosis can be a challenge and the diagnosis is usually made following postoperative histopathologic examination. Understanding the clinicopathological characteristics of this tumour is vital for accurate preoperative diagnosis, which can be essential for planning of care and treatment for patients. Along with a review of the current literature, we present a case of a young female with SST. This patient presented with prolonged menstrual bleeding. She underwent total abdominal hysterectomy with right salpingo-oophorectomy and left salpingectomy. The histopathological examination revealed the salient features of SST like cellular heterogeneity, hemangiopericytoma (HPC) like vascular structures, and a pseudo lobular architecture with cellular nodules separated by hypocellular, oedematous, and collagenous stroma, hence confirming the diagnosis. This case highlights the importance of considering SST as a differential diagnosis, in young patients with ovarian mass having the morphological and histopathological characteristics, despite its rarity in occurrence.
Metaplastic carcinoma breast in male – A case report and review of literature
Authors: Dubey Priyesh , Babu M C Suresh , Premalatha C S , Lokesh K N , Rudresha A H , Rajeev L K , Saldanha Smitha , Jacob Linu Abraham , Pandey Amit
Published: May 2022

Male breast cancers are rare and account for 1% of all breast cancer cases reported annually. Incidence of metaplastic breast cancer in females is less than 1% thus metaplastic breast cancers in males are even rarer. Larger tumour size and higher grade differentiate them from invasive carcinoma. They are also more aggressive than invasive carcinoma. On IHC these are typically oestrogen- and progesterone-receptor, Her 2 neu negative. Here we report a rare case of a 35-year-old male patient who presented with left chest wall swelling for six months, histopathological examination showed it to be metaplastic carcinoma breast. The patient underwent left MRM and adjuvant chemotherapy.
Metaphors by Iranian Youth about Marriage based on Metaphorical Theory
Authors: Dehdast Kowsar
Published: May 2022

Aim: The aim of this study was to investigate young people's metaphors of "marriage" based on the cognitive metaphorical theory of Lakoff and Johnson. Methods: In line with the goal of this research, and in order to obtain the lived experiences of individuals, phenomenological methodology in qualitative study was used. The study population was married youth who volunteered to be interviewed in this field and based on the principle of theoretical sampling and data saturation, 13 people were interviewed. Results: This study showed how the Iranian youth understand the concept of marriage in such a way that the nature of marriage is a purposeful journey that is created by spouses. The existence of origin, destination, purposefulness, human corridor and movement, and finally the necessities of a healthy and successful transition to this destination, is seen positively to explain "way" as my nickname "marriage". Conclusion: Findings indicate that in this regard, the approach of educational counseling should be resorted to, in addition to the purpose and destination of the couple in marriage, their goals in life in terms of value and semantic changes in society and discourses involving spouses around the concept of marriage was examined.
The Effectiveness of Acceptance and Commitment Therapy (ACT) on Anxiety and Self-efficacy of Children: A Single-Case Experimental Design
Authors: Nekooei Somayeh , Abbaspour Zabihollah , Koraei Amin
Published: May 2022

Aim: The aim of the current study was to investigate the effectiveness of Acceptance and Commitment Therapy (ACT) on Anxiety and Self-efficacy of children among children with anxiety. Methods: The statistical population consisted of all children diagnose with anxiety in Ahvaz. The research sample consisted of 3 children that were selected according to the results of the Child Anxiety Related Emotional Disorders (SCARED) , using purposeful sampling method. In this research, a single-case experimental design, type of non-concurrent multiple baseline designs was used. To evaluate the anxiety, Child Anxiety Related Emotional Disorders (SCARED) and self-Efficacy - Children's Self-Efficacy Scale were used. The data was collected in three phases of baseline, during intervention, and one month follow-up. Findings: The findings indicate that the subjects in the treatment phase experienced improvement in anxiety (30/96) and self-efficacy (28/13), and in the follow-up in regards to anxiety (38/44) and self-efficacy (32/25). The change index was indicative of meaningful changes (z=1/95 α=0.05). Conclusion: Therefore, the research findings illustrated that Acceptance and Commitment Therapy reduces anxiety and increases children's self-efficacy by increasing psychological flexibility and reducing dysfunctional reactions.
Investigating the Mediating Role of Identity Crisis and Family Cohesion in Determining the Relationship between Social Networks Participation with Body Image Issues Among Students
Authors: Nemati Fatemeh , Boland Hasan , Sayadi Ali
Published: May 2022

Aim: The aim of present study was to investigate the mediating role of identity crisis and family cohesion in determining the relationship between participation in social media and body image concerns among students. Methods: The present study was a descriptive correlational study. The statistical population consisted of all public middle school students studying in the city of Rasht in the academic year of 2019-20. Participants were selected using multi-stage cluster random sampling method. To collect data from four questionnaires, Social Network Sites Engagement Scale (Boland1399), Identity Crisis (Ahmadi, 1997), Family Cohesion (Samani, 2002) and Body Image Concern Questionnaire (Littleton et al., 2005) were used. These questionnaires were provided to students online and 674 people responded to them. Finally, 497 questionnaires were examined and analyzed statistically, using path analysis method. Findings: The results showed that social network engagement has a direct effect on body image concern (β=-0.41, P<0.001), family cohesion (β=-0.25, P <0.001), and identity crisis (Β=-0.16, P<0.001). Identity crisis directly and significantly predicts body image concerns (β=-0.13, P<0.001). Family cohesion directly and significantly predicts body image concerns (β=-0.17, P<0.001). In addition,that engagement in social networks mediated by identity crisis has an indirect impact on body image anxiety (β=0.06, P<0.001). However, the indirect effect of the mediating variable of family cohesion on social network engagement and body image concerns is not statistically significant. Conclusion: Therefore, improving the amount and manner of adolescents' use of social networks, teaching media literacy to adolescents and holding training sessions to facilitate the transition from puberty and prevent identity crisis is important to reduce dissatisfaction with body image and promote adolescent mental health.
A comparative analysis of the first cycle degree programmes in business in Turkey in terms of the number of course units and the student workloads
Authors: Sarıgül Haşmet , Şengelen Hakan Eren
Published: May 2022

This comparative study aims to determine the differences between the curricula of the first cycle degree programmes in business in Turkey in terms of the number of course units and the student workloads. In this context, (1) the courses included in the Bologna course information packages of business schools on their web sites have been examined; (2) course units have been gathered together in content–related groups, (3) the numbers of course units in each content–related group have been determined, (4) total student workload of each content–related group has been determined by means of the institutionally allocated ECTS credits, (5) the differences between public and foundation business schools have been tested for each content–related group in terms of total number of course units and total student workload, and (6) the differences between the business schools using Turkish and those using a foreign language as the medium of instruction have been tested for each content–related group in terms of total number of courses and total student workload. The methods used in the research are document review and multivariate analysis. The data of 147 business schools has been used in the study and the outputs of the research reveal that there are significant differences in most of the content–related groups between both the business school groupings described above at points (5) and (6) in terms of the number of course units and student workload.

Received: 9 October 2020Accepted: 22 April 2022
UAE-based first-year university students’ perception of lifelong learning skills affected by COVID-19
Authors: Deveci Tanju
Published: May 2022

Forcing education institutions to rely on online learning exclusively, the recent pandemic has brought lifelong learning (LLL) to the forefront. The effects of the recent education approaches on students’ LLL skills merit investigation. First-year students may be at a greater risk because of their limited tertiary education experience and universities’ expectations for them to engage in self-directed learning. This study investigated how 38 UAE-based first-year students thought COVID-19 impacted their LLL skills. The quantitative data were collected using a scale while the qualitative data were collected using a reflective task. The results revealed that the students’ overall high score from the scale prior to the pandemic remained stable nine months into it despite a significant decrease in the adaptable learning strategies sub-scale. Yet, some students’ overall LLL scores increased significantly. The qualitative data showed that these students thought they solidified their skills in learning strategies and plans. However, the female students reported a decrease in goal-setting score. Taken together, the results indicate that LLL skills help students reduce the negative impacts of COVID-19 on learning; yet it is still important to note the reducing impact of the pandemic on some students’ skill in adapting learning strategies and setting goals. The results also indicate that LLL skills are malleable and educators can help enhance students’ LLL skills.

Received: 20 April 2021Accepted: 20 April 2022
Emergency remote education: A perspective of its potentialities and limitations in a Peruvian university
Authors: Barrutia Barreto Israel , Patricio Aparicio Santiago Saturnino
Published: May 2022

This research aims to identify the potentialities and limitations of emergency remote education in the Peruvian university context as a consequence of the COVID-19 pandemic based on teachers’ experience of the Hermilio Valdizán National University (UNHEVAL). The type of this research was descriptive and the sample consisted of 123 teachers of the academic period 2020-I. For the data collection, a questionnaire was used, whose validation was made through the judgment of experts (0.96) and the reliability of the results through the Z-test. According to the results, flexibility stands out between the potentialities in regards to topics’ distribution, time, and the possibility to produce greater interest in the participants. It was observed that time flexibility is not considered as favorable unlike what was detected through literature. Infrastructure stands out, especially when is related to the connectivity and Internet access as well as the distractors produced by the easy access to devices and applications that are not related to the class session. The paper revealed weakness in the digital competencies of both teachers and students, and the scarce level of social interaction caused by social isolation. It is concluded that the potentialities and limits of emergency remote education in a Peruvian university are conditioned by different elements specific to each context or country and must be considered for the production of new educational proposals as a policy of prevention of the possibility of new events that require mandatory isolation.

Received: 1 July 2021Accepted: 19 April 2022
Factors influencing postgraduate students’ intention to use learning management system
Authors: Samaila Kamaludeen , Khambari Mas Nida Md. , Kumar Jeya Amantha , Masood Mona
Published: May 2022

Learning management systems (LMS) are continuously being implemented in tertiary institutions to manage and strengthen educational activities. LMS such as Moodle facilitates the management of learning content, collaboration, and communication. However, there have been limited studies examining factors influencing postgraduate students’ intention to use LMS in Malaysian universities, as studies mainly concentrate on undergraduates’ use intentions. Therefore, this study investigates factors influencing the behavioural intention to use LMS based on the Unified Theory of Acceptance and Use of Technology (UTAUT) model. The results indicated performance expectancy (PE) followed by social influence (SI) and effort expectancy (EE) as the factors influencing the behavioural intention (BI) to use LMS. Concurrently, facilitating conditions (FC) were found not to influence BI, and we denote that socio-economy standings and maturity influence their overall acceptance of the LMS. Practical and theoretical implications are discussed accordingly.

Received: 13 August 2021Accepted: 11 April 2022
Virtual education during COVID-19 in higher education: A systematic review
Authors: Torres-Caceres Fatima del Socorro , Méndez-Vergaray Juan , Rivera-Arellano Edith Gissela , Ledesma-Cuadros Mildred Jénica , Huayta-Franco Yolanda Josefina , Flores Edward
Published: May 2022

The objective of the present systematic review aimed to analyze studies linked to online teaching-learning, digital competence tutoring, and technological tools in virtual education during COVID-19 in higher education. The suggested methodology by the PRISMA declaration was pursued; the information search was conducted in Scopus, EBSCO, Springer Open, ProQuest, and One File. The target period ranged from May 10, 2021, to July 4, 2021; the identification, screening, eligibility, and inclusion for its progress were performed. The search produced a total of 230 studies, with 45 remaining. The inclusion criteria included original peer-reviewed research articles and qualitative and quantitative studies in higher education, comprising teachers and students addressing the study objective. In contrast, the exclusion criteria covered bibliographic reviews with procedural deficiencies, studies not exposed to a peer review process, and those not depicting a relationship with parts of the study. The results reveal that online teaching-learning, digital competence tutoring, and technological tools have been affirmative features expected to persist in higher virtual education engendered by the COVID-19 pandemic.

Received: 5 October 2021Accepted: 22 April 2022
Visual Business Analytics: Using the Example of a Call Center
Authors: Nollenburg Pascal-Philipp , Dill Arthur
Published: May 2022

In this article we will examine an approach to the analysis of semi-structured log data using the example of a call center as a subsection of a central corporate service center. In such data all events of a caller passing through the routing are stored. Consequently, it is possible to trace more precisely what the customer experiences during his call. However, this information is only available in semi-structured form. A little-known approach in Anglo-Saxon literature, the Visual Business Analytics (VBA), represents a holistic concept for achieving added value from semi-structured data. In the VBA, data is initially transformed and structured and then prepared for analysis purposes. The goal is to derive recommendations for supporting management decisions in a call center. In the further course, the development of the approaches of information representation is examined first, then the VBA is presented and applied to the log protocols in a call center. Finally, other call center applications of VBA are considered, and an outlook is given on other industries in which the use of VBA offers advantages.
Cost and Return Analysis of Kharif Sorghum (Sorghum bicolor) in Bhilwara District, Rajasthan
Authors: Meena G.L. , Sharma Latika , Singh Hari , Bairwa Kailash Chand , Kumar Keshav
Published: May 2022

Background: Sorghum is a heat and drought resistant crop that is widely grown in arid and semi-arid regions for food, feed and bio-energy. The sorghum crop is important to the majority of farmers for income, nutritional security and environmental sustainability. They grow sorghum not for profit, but because it is the only crop that can withstand the harsh climatic conditions that exist. The present study aimed to investigate the economics of sorghum in the Bhilwara district of Rajasthan during the year 2020-21 using primary data from 60 sample households from four different villages. Methods: The standard cost concept method of the Commission for Agricultural Cost and Price (CACP) was used to calculate the cost of cultivation (COC) of sorghum crop. It includes Cost A1, Cost A2, Cost B1, Cost B2, Cost C1, Cost C2 and Cost C3. Farm income measures, which include gross income, farm business income, family labour income and net income, are used to determine crop profitability and return on investment. Result: The results of study revealed that total cost (Cost C2) of sorghum cultivation per ha was found to be ₹ 25149.69. The cost of producing one quintal of sorghum was calculated to be ₹ 1383.18. Sorghum cultivation generated a net income, farm business income and family labour income of ₹ 23658.44, ₹ 30680.32 and ₹ 26527.74 per ha, respectively.
Assessment of Crop Production Dynamics in Mizoram
Authors: . Rohlupuii , Kaur Arjinder , Kataria Poonam , Priscilla Laishram
Published: May 2022

Background: Mizo have been agriculturists from the beginning of the 18th century. They know only the form of farming known as shifting cultivation which forms the major activity of the Mizo economic life even today. Jhuming locally known as ‘Tlangramloneih’ is the only occupation and has a close link to their culture and tradition. It is the way of life and almost all the activities of the Mizo’s revolve around it. Methods: The data in Mizoram with respect to area, production and yield of major agricultural crops, fruits and vegetables were based on secondary data. Decade wise analysis of growth rate, instability index and decomposition analysis were done to study the crop production dynamics in the state. Result: Results revealed that during overall period, the growth rate in area, production and yield was negative for field crops except for sugarcane which was positive. For fruits and vegetables, the growth rate in area and production were positive for cabbage, birdeye chilli and banana whereas yield showed negative growth in all the studied fruits and vegetables. In general, the area effect was higher than the yield and interaction effect for all food grains and fruits and vegetables leading to the suggestion that steps should be taken to improve their productivity.