bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary figures 1-7 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: March 2023

Supplementary figures 1-7. Contains the 7 supplementary figures (1S to 7S) in PDF format. Fig. 1S: Characterization of the expression of class-3 semaphorin receptors in LEC Fig. 2S: Semaphorins that fail to contract LEC nevertheless induce contraction of other cell types. Fig. 3S: Measurement of cell contraction using the xCELLigence dual plate (RTCA) machine and FR-sema3C induced changes in in thentent of M2 macrophages in the tumors. Fig. 4S: Inhibition of BrdU incorporation in lEC by FR-sema3C. Fig. 5S: The effect of FR-sema3C on the Distribution of intrtumoral and peritumoral lymphatics Fig. 6S: The effect of tumor size on the development of lymph node metastases. Fig. 7: P65-Sema3C promotes the survival of A549 lung cancer cells.
supplementary figure 1 from Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia
Authors: Kim Jin-A , Shim Jae-Seung , Lee Ga-Young , Yim Hyeon Woo , Kim Tae-Min , Kim Myungshin , Leem Sun-Hee , Lee Jong-Wook , Min Chang-Ki , Oh Il-Hoan
Published: March 2023

supplementary figure 1: alterations of mesenchymal cell colonization and proliferation in the bone marrow samples of acute myeloid leukemia (AML) patients.
supplemental figure legends from Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia
Authors: Kim Jin-A , Shim Jae-Seung , Lee Ga-Young , Yim Hyeon Woo , Kim Tae-Min , Kim Myungshin , Leem Sun-Hee , Lee Jong-Wook , Min Chang-Ki , Oh Il-Hoan
Published: March 2023

supplemental figure legends
Supplementary Figure 4 from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Authors: Lau Jasmine , Ilkhanizadeh Shirin , Wang Susan , Miroshnikova Yekaterina A. , Salvatierra Nicolas A. , Wong Robyn A. , Schmidt Christin , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: March 2023

Figure S4: Murine and human proneural HGG cells exposed to IR in vitro display reduced cell stiffness, reduced proliferation and increased TMZ resistance.
Supplementary Figure 2 from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Authors: Lau Jasmine , Ilkhanizadeh Shirin , Wang Susan , Miroshnikova Yekaterina A. , Salvatierra Nicolas A. , Wong Robyn A. , Schmidt Christin , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: March 2023

Figure S2: Fractionated doses of radiation extend survival and induce a PMT in proneural HGG murine model.
Supplementary Table S1 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Supplementary Table S1. Microarray analysis.
Supplementary Figure S4 from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Supplementary Figure S4. Cell line screening.
Supplemental Figure Legends from Identification of Oncogenic and Drug-Sensitizing Mutations in the Extracellular Domain of FGFR2
Authors: Tanizaki Junko , Ercan Dalia , Capelletti Marzia , Dodge Michael , Xu Chunxiao , Bahcall Magda , Tricker Erin M. , Butaney Mohit , Calles Antonio , Sholl Lynette M. , Hammerman Peter S. , Oxnard Geoffrey R. , Wong Kwok-Kin , Jänne Pasi A.
Published: March 2023

Supplemental Figure Legends
Supplementary Figure Legend from A Systematic Approach to Defining the microRNA Landscape in Metastasis
Authors: Mudduluru Giridhar , Abba Mohammed , Batliner Jasmin , Patil Nitin , Scharp Maike , Lunavat Taral R. , Leupold Jörg Hendrik , Oleksiuk Olga , Juraeva Dilafruz , Thiele Wilko , Rothley Melanie , Benner Axel , Ben-Neriah Yinon , Sleeman Jonathan , Allgayer Heike
Published: March 2023

Legends for Supplementary Figures S1-S7.
Supplementary Figures S1-S10 from Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
Authors: Bagley Alexander F. , Scherz-Shouval Ruth , Galie Peter A. , Zhang Angela Q. , Wyckoff Jeffrey , Whitesell Luke , Chen Christopher S. , Lindquist Susan , Bhatia Sangeeta N.
Published: March 2023

Tumor accumulation of AS750 after PEG-NR heat exposure with varying delta T (S1); Diminished window of tumor transport after re-exposure to PEG-NR heating (S2); Animal weights during PEG-NR and doxorubicin liposome therapeutic trial (S3); Transvascular transport in tumors after single exposure and re-exposure to PEGNR heating (S4); Vascular endothelial growth factor (VEGF) expression in PEG-NR heated tumors (S5); Endothelial cell F-Actin dynamics during heat exposure and recovery (S6); Visualizing PEG-NRs in the tumor microenvironment using multiphoton microscopy (S7); Cargo accumulation in tumors with Hsf1+/+ and Hsf1-/- vasculature after single exposure to PEG-NR heating (S8); HSF1 expression in tumor-associated vasculature following PEG-NR heating (S9); Size-dependent macromolecular extravasation from the unheated vasculature (S10).
Supplementary Information, Figures 1-3, Tables 2-11 from An In Vivo Method to Identify microRNA Targets Not Predicted by Computation Algorithms: p21 Targeting by miR-92a in Cancer
Authors: Su Xiaoping , Wang Huaming , Ge Wei , Yang Mingjin , Hou Jin , Chen Taoyong , Li Nan , Cao Xuetao
Published: March 2023

Supplementary Information, Figures 1-3, Tables 2-11. Supplementary Figure 1 - Supplementary Figure 1. Alignment analysis of the most enriched miRNAs and their targeting mRNAs. Supplementary Figure 2 - Supplementary Figure 2. miR-92a down-regulates the expression of p21 in PC-3 cells. Supplementary Figure 3 - Supplementary Figure 3. Compared expression of miRNAs in total RNA to that in miRIP isolation by using p21 probe in HepG2 cells. Supplementary Table 2. Relative miRIP isolation of miRNAs predicted by PicTar in HepG2 and PC-3 cells. Supplementary Table 3. Relative miRIP isolation of miRNAs predicted by PITA in HepG2 and PC-3 cells. Supplementary Table 4. Relative miRIP isolation of miRNAs predicted by miRanda in HepG2 and PC-3 cells. Supplementary Table 5. Relative miRIP isolation of miRNAs predicted by RNA22 in HepG2 and PC-3 cells. Supplementary Table 6. Relative miRIP isolation of miRNAs predicted by TargetScan in HepG2 cells. Supplementary Table 7. Relative miRIP isolation of miRNAs predicted by PicTar in HepG2 cells. Supplementary Table 8. Relative miRIP isolation of miRNAs predicted by PITA in HepG2 cells. Supplementary Table 9. Relative miRIP isolation of miRNAs predicted by miRanda in HepG2 cells. Supplementary Table 10. Relative miRIP isolation of miRNAs predicted by RNA22 in HepG2 cells. Supplementary Table 11. All primers and probes used in this study.
Supplemental Table 2 from Distinct Luminal-Type Mammary Carcinomas Arise from Orthotopic Trp53-Null Mammary Transplantation of Juvenile versus Adult Mice
Authors: Nguyen David H. , Ouyang Haoxu , Mao Jian-Hua , Hlatky Lynn , Barcellos-Hoff Mary Helen
Published: March 2023

Genes modulated by at least 1.5-fold in tumors arising in juvenile hosts relative to those from adult hosts.
Supplementary Table 1A-C from Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
Authors: Takeuchi Shintaro , Baghdadi Muhammad , Tsuchikawa Takahiro , Wada Haruka , Nakamura Toru , Abe Hirotake , Nakanishi Sayaka , Usui Yuu , Higuchi Kohtaro , Takahashi Mizuna , Inoko Kazuho , Sato Syoki , Takano Hironobu , Shichinohe Toshiaki , Seino Ken-ichiro , Hirano Satoshi
Published: March 2023

Supplementary Table A. Association between GM-CSF and clinicopathological variables Supplementary Table B. Clinicopathological features of enrolled PDAC patients with or without chemotherapy Supplementary Table C. Clinicopathological features including drug regimen or chemotherapeutic response of enrolled 6 PDAC patients with pre-operative chemotherapy.
Supplemental Methods and References from miR-181a-5p Inhibits Cancer Cell Migration and Angiogenesis via Downregulation of Matrix Metalloproteinase-14
Authors: Li Yiyi , Kuscu Cem , Banach Anna , Zhang Qian , Pulkoski-Gross Ashleigh , Kim Deborah , Liu Jingxuan , Roth Eric , Li Ellen , Shroyer Kenneth R. , Denoya Paula I. , Zhu Xiaoxia , Chen Longhua , Cao Jian
Published: March 2023

Supplemental Methods and References. Description of additional methods and procedures used in the study. Also includes Supplemental References.
Supplementary Figure 4 from Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
Authors: Takeuchi Shintaro , Baghdadi Muhammad , Tsuchikawa Takahiro , Wada Haruka , Nakamura Toru , Abe Hirotake , Nakanishi Sayaka , Usui Yuu , Higuchi Kohtaro , Takahashi Mizuna , Inoko Kazuho , Sato Syoki , Takano Hironobu , Shichinohe Toshiaki , Seino Ken-ichiro , Hirano Satoshi
Published: March 2023

Blockade of GM-CSF contributes to the recovery of CD8+ T cells proliferation when cultured with monocytes stimulated with chemotherapy-treated PDAC CM.
Supplementary Table S1 from α-Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration
Authors: Boggs Amanda E. , Vitolo Michele I. , Whipple Rebecca A. , Charpentier Monica S. , Goloubeva Olga G. , Ioffe Olga B. , Tuttle Kimberly C. , Slovic Jana , Lu Yiling , Mills Gordon B. , Martin Stuart S.
Published: March 2023

Supplementary Table S1. Patient characteristics for survival analysis.
Supplementary Figure 1 from Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
Authors: Takeuchi Shintaro , Baghdadi Muhammad , Tsuchikawa Takahiro , Wada Haruka , Nakamura Toru , Abe Hirotake , Nakanishi Sayaka , Usui Yuu , Higuchi Kohtaro , Takahashi Mizuna , Inoko Kazuho , Sato Syoki , Takano Hironobu , Shichinohe Toshiaki , Seino Ken-ichiro , Hirano Satoshi
Published: March 2023

5-FU-treated Capan-1 supernatants induce the differentiation of monocytes into MDSCs.
Supplementary Figure S4 from α-Tubulin Acetylation Elevated in Metastatic and Basal-like Breast Cancer Cells Promotes Microtentacle Formation, Adhesion, and Invasive Migration
Authors: Boggs Amanda E. , Vitolo Michele I. , Whipple Rebecca A. , Charpentier Monica S. , Goloubeva Olga G. , Ioffe Olga B. , Tuttle Kimberly C. , Slovic Jana , Lu Yiling , Mills Gordon B. , Martin Stuart S.
Published: March 2023

Supplementary Figure S4. Patient ages and pathological diagnosis for 144 matched patient samples.
Supplemental Table S4 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Table S4. Summary statistics for tumor volume measurements in the mixed linear regression analysis in PANC-1 tumor xenografts.
Supplementary Figures S1-S7 from Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell–Mediated Antitumor Immunity
Authors: Derouazi Madiha , Di Berardino-Besson Wilma , Belnoue Elodie , Hoepner Sabine , Walther Romy , Benkhoucha Mahdia , Teta Patrick , Dufour Yannick , Yacoub Maroun Céline , Salazar Andres M. , Martinvalet Denis , Dietrich Pierre-Yves , Walker Paul R.
Published: March 2023

Peptides and proteins used in the study, with all the minimal epitopes including 4 flanking residues (S1); Purified proteins were analyzed by Coomassie blue and Western Blot (S2); Z12 transports efficiently its cargo into the cytoplasm of DC (S3); Choice of adjuvant influences proportions of effector and memory phenotype antigen-specific CD8+ T cells induced after Z12-OVALP vaccination (S4); Persistance of antigen-specific cytotoxic T cells after vaccination (S5); Balance of brain tumor infiltrating lymphocytes is altered by Z12-OVALP vaccination (S6); Effector cytokine expression by brain tumor infiltrating CD8+ T cells is augmented by Z13-MultiE2 vaccination (S7).
Supplemental Figures S1-S5 from Breast Cancer Cells Respond Differentially to Modulation of TGFβ2 Signaling after Exposure to Chemotherapy or Hypoxia
Authors: O'Brien Siobhan K. , Chen Liang , Zhong Wenyan , Armellino Douglas , Yu Jiyang , Loreth Christine , Follettie Maximillian , Damelin Marc
Published: March 2023

Supplemental Figures S1-S5: Fig. S1: SKBR3 cells exposed to epirubicin or hypoxia expressed the same isoforms of CD44 and comparable levels of the apoptotic marker Annexin V. Fig. S2: Colonies that grew from sorted cells exhibited heterogeneity in CD44 expression as in the original cell culture. Fig. S3: TGFβ-2 mRNA expression is induced in CD44hi compared to CD44-/lo SKBR3 cells after epirubicin treatment or hypoxia. Fig. S4: The dichotomy of response to TGF-β2 was also observed when cells were sorted by Aldefluor activity. Fig. S5: MCF7 breast cancer cells, like SKBR3 cells, gave rise to two distinct populations after exposure to epirubicin and hypoxia.
Supplementary Table SIII from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis
Authors: Oei Arlene L. , van Leeuwen Caspar M. , ten Cate Rosemarie , Rodermond Hans M. , Buist Marrije R. , Stalpers Lukas J.A. , Crezee Johannes , Kok H. Petra , Medema Jan Paul , Franken Nicolaas A.P.
Published: March 2023

Values of the linear quadratic parameters, Î± and Î², of both cervical cancer cell lines SiHa and HeLa after radiation alone and after radiation + hyperthermia.
Supplementary Tables S1-S4 from Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
Authors: Eberlein Catherine A. , Stetson Daniel , Markovets Aleksandra A. , Al-Kadhimi Katherine J. , Lai Zhongwu , Fisher Paul R. , Meador Catherine B. , Spitzler Paula , Ichihara Eiki , Ross Sarah J. , Ahdesmaki Miika J. , Ahmed Ambar , Ratcliffe Laura E. , O'Brien Elizabeth L. Christey , Barnes Claire H. , Brown Henry , Smith Paul D. , Dry Jonathan R. , Beran Garry , Thress Kenneth S. , Dougherty Brian , Pao William , Cross Darren A.E.
Published: March 2023

Supplementary Tables S1-S4. Generation of resistant cell populations (S1); Small molecule inhibitors (S2); IC50 (µM) values from cell growth inhibition assays comparing compound sensitivity between parental and resistant cell populations (S3); Genetic analysis of resistant cell populations (S4).
Supplementary Figure S3 from Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis
Authors: Oei Arlene L. , van Leeuwen Caspar M. , ten Cate Rosemarie , Rodermond Hans M. , Buist Marrije R. , Stalpers Lukas J.A. , Crezee Johannes , Kok H. Petra , Medema Jan Paul , Franken Nicolaas A.P.
Published: March 2023

Expression of p53 and E6 with immunohistochemistry and western blot in SiHa and HeLa cells after radiation, hyperthermia and cDDP treatment in the presence or absence of bafilomycin, chloroquine and MG132.
Supplementary Figures S1-S4 from Macrophages Regulate the Systemic Response to DNA Damage by a Cell Nonautonomous Mechanism
Authors: Geiger-Maor Anat , Guedj Avital , Even-Ram Sharona , Smith Yoav , Galun Eithan , Rachmilewitz Jacob
Published: March 2023

Supplementary Figures S1-S4. Kinetics of DEN induced DNA damage and macrophage recruitment (S1); Regulation of oxidative-induced DNA damage response by HB-EGF (S2); The EGFR pathway modulates DSBs repair and cell fate following peroxide treatment (S3); A suggested model for macrophage-derived cell non-autonomous DNA damage response and repair (S4).
Supplemental Table 3 from A Chemical Genetics Approach for the Functional Assessment of Novel Cancer Genes
Authors: Zhou Qianhe , Derti Adnan , Ruddy David , Rakiec Daniel , Kao Iris , Lira Michelle , Gibaja Veronica , Chan HoMan , Yang Yi , Min Junxia , Schlabach Michael R. , Stegmeier Frank
Published: March 2023

Supplemental Table 3: List of alternatively spliced genes identified in response to SF3B1 mutant
Supplemental Methods, Figures 1 - 12, Tables 1 - 2, 4 from A Chemical Genetics Approach for the Functional Assessment of Novel Cancer Genes
Authors: Zhou Qianhe , Derti Adnan , Ruddy David , Rakiec Daniel , Kao Iris , Lira Michelle , Gibaja Veronica , Chan HoMan , Yang Yi , Min Junxia , Schlabach Michael R. , Stegmeier Frank
Published: March 2023

Supplemental Figure 1. Efficient knockâ€�in of DDâ€�domain into the endogenous p53 locus by TALENs in HCT116 cells. Supplemental Figure 2. PCR verification of Degronâ€�KI clones. Supplemental Figure 3. Immunofluorescence staining of Degronâ€�KI cells. Supplemental Figure 4. Quantification of DD tagged proteins in the presence or absence of Shld. Supplemental Figure 5. Highly efficient Degronâ€�KI at the endogenous EZH2 locus by CRISPR in HCT116. Supplemental Figure 6. Assessment of the kinetics of DDâ€�EZH2 and DDâ€�SF3B1 depletion upon Shld withdrawal. Supplemental Figure 7. HCT116 (EZH2 wild type) cells are not sensitive to EZH2 inhibitor EI1. Supplemental Figure 8. RTâ€�PCR strategy to identify alleleâ€� specific DD tagging of mutant versus wildtype SF3B1. Supplemental Figure 9. UQCC and CRNDE exhibit an altered splice pattern in SF3B1 mutant uveal melanoma cell lines. Supplemental Figure 10. Shld has minimal effects on gene expression of parental Mel202 cells and Mel202 DDâ€�mutâ€�SF3B1. Supplemental Figure 11. Selective depletion of mutant SF3B1 in Mel202 Degronâ€�KI cells reversed the alternative splicing pattern of DYNLL1, SNRPN, TMEM14C, ABCC5, ZDHHC16, RBM18. Supplemental Figure 12. Selective depletion of mutant SF3B1 in Mel202 Degronâ€�KI cells by Shld withdrawal predominantly alters 3' splice sites but not 5' splice site selection. Supplemental Figure 13. Confirmation that the DD tag insertion occurred exclusively at the SF3B1 locus in Degronâ€�KI engineered Mel202 clones. Supplemental Table 1: Detailed genotypes of ESSâ€�1 Degronâ€�KI clones. Supplemental Table 2: Detailed genotypes of Mel202 Degronâ€�KI clones. depletion using MATS. Supplemental Table 4: Comparison of the alternatively spliced genes identified in this study with genes reported in prior reports (5).
Supplementary Tables S1-S2; Figures S1-S9 from Paracrine WNT5A Signaling Inhibits Expansion of Tumor-Initiating Cells
Authors: Borcherding Nicholas , Kusner David , Kolb Ryan , Xie Qing , Li Wei , Yuan Fang , Velez Gabriel , Askeland Ryan , Weigel Ronald J. , Zhang Weizhou
Published: March 2023

Supplementary Table S1. Index of genes upregulated or downregulated in basal-TIC tumors relative to luminal-TIC tumors. Supplementary Table S2. WNT5A CNV by PAM50 molecular subtype from samples with both RNAseq expression data and CNV (n=807). Figure S1: Verification of Illumina Array by reverse transcription real-time PCR analysis (Supplementary for Figure 1). Figure S2: Allelic loss of WNT5A led to decreased WNT5A expression in human breast-cancer specimens and mouse luminal epithelial cells. Figure S3: Schematic depiction of the purification procedure for different populations of mammary epithelial cells. Figure S4: Supplementary information of Figure 4. Figure S5: Heterozygous deletion of Wnt5a has no impact on normal mammary gland development. Figure S6: WNT5A induces the phosphorylation of SMAD2. Figure S7: Differential expression of canonical and noncanonical Wnt receptors in basal and luminal epithelial cells. Figure S8: RYK or SMAD2 expression does not correlate with metastasis-free survival. Figure S9: Schematic depiction of the major conclusions and explained in detail in the Discussion section.
Supplementary Materials and Methods and Supplementary Figure Legends from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Authors: Hurley Paula J. , Hughes Robert M. , Simons Brian W. , Huang Jessie , Miller Rebecca M. , Shinder Brian , Haffner Michael C. , Esopi David , Kimura Yasunori , Jabbari Javaneh , Ross Ashley E. , Erho Nicholas , Vergara Ismael A. , Faraj Sheila F. , Davicioni Elai , Netto George J. , Yegnasubramanian Srinivasan , An Steven S. , Schaeffer Edward M.
Published: March 2023

This file consists of the Supplementary Materials and Methods and the Supplementary Figure Legends.
Supplementary Figure S2 from Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma
Authors: Schmithals Christian , Köberle Verena , Korkusuz Hüdayi , Pleli Thomas , Kakoschky Bianca , Augusto Eduardo Alonso , Ibrahim Ahmed Atef , Arencibia Jose M. , Vafaizadeh Vida , Groner Bernd , Korf Horst-Werner , Kronenberger Bernd , Zeuzem Stefan , Vogl Thomas J. , Waidmann Oliver , Piiper Albrecht
Published: March 2023

Supplementary Figure S2: Body weight of HepG2 xenograft-bearing mice treated with iRGD, control (Ctl.) peptide, PBS and doxorubicin.
Supplementary Figure S5. SPARCL-1 coated beads do not reinforce cellular traction. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Authors: Hurley Paula J. , Hughes Robert M. , Simons Brian W. , Huang Jessie , Miller Rebecca M. , Shinder Brian , Haffner Michael C. , Esopi David , Kimura Yasunori , Jabbari Javaneh , Ross Ashley E. , Erho Nicholas , Vergara Ismael A. , Faraj Sheila F. , Davicioni Elai , Netto George J. , Yegnasubramanian Srinivasan , An Steven S. , Schaeffer Edward M.
Published: March 2023

Supplementary Figure S5
Supplementary Figure S4. SPARCL1 inhibits cytoskeletal remodeling. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Authors: Hurley Paula J. , Hughes Robert M. , Simons Brian W. , Huang Jessie , Miller Rebecca M. , Shinder Brian , Haffner Michael C. , Esopi David , Kimura Yasunori , Jabbari Javaneh , Ross Ashley E. , Erho Nicholas , Vergara Ismael A. , Faraj Sheila F. , Davicioni Elai , Netto George J. , Yegnasubramanian Srinivasan , An Steven S. , Schaeffer Edward M.
Published: March 2023

Supplementary Figure S4
Supplementary Figure S2. AR directly represses SPARCL1 expression in prostate cancer. from Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression
Authors: Hurley Paula J. , Hughes Robert M. , Simons Brian W. , Huang Jessie , Miller Rebecca M. , Shinder Brian , Haffner Michael C. , Esopi David , Kimura Yasunori , Jabbari Javaneh , Ross Ashley E. , Erho Nicholas , Vergara Ismael A. , Faraj Sheila F. , Davicioni Elai , Netto George J. , Yegnasubramanian Srinivasan , An Steven S. , Schaeffer Edward M.
Published: March 2023

Supplementary Figure S2
Supplementary Figure 3 from c-Myc Alterations Confer Therapeutic Response and Acquired Resistance to c-Met Inhibitors in MET-Addicted Cancers
Authors: Shen Aijun , Wang Lu , Huang Min , Sun Jingya , Chen Yi , Shen Yan-Yan , Yang Xinying , Wang Xin , Ding Jian , Geng Meiyu
Published: March 2023

Supplementary Figure 3-c-Myc determines clinical response and resistance for c-Met targeted therapy.
Supplementary Figure Legend from Effects of Sorafenib Dose on Acquired Reversible Resistance and Toxicity in Hepatocellular Carcinoma
Authors: Kuczynski Elizabeth A. , Lee Christina R. , Man Shan , Chen Eric , Kerbel Robert S.
Published: March 2023

Supplementary Figure Legend. Legends for Supplementary Figures S1-S5.
Supplementary Figure 1 from c-Myc Alterations Confer Therapeutic Response and Acquired Resistance to c-Met Inhibitors in MET-Addicted Cancers
Authors: Shen Aijun , Wang Lu , Huang Min , Sun Jingya , Chen Yi , Shen Yan-Yan , Yang Xinying , Wang Xin , Ding Jian , Geng Meiyu
Published: March 2023

Supplementary Figure 1-Multiple kinases are co-activated in c-Met-resistant cells.
Supplementary Tables S1-S2 from Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis
Authors: Kirane Amanda , Ludwig Kathleen F. , Sorrelle Noah , Haaland Gry , Sandal Tone , Ranaweera Renate , Toombs Jason E. , Wang Miao , Dineen Sean P. , Micklem David , Dellinger Michael T. , Lorens James B. , Brekken Rolf A.
Published: March 2023

Supplementary Tables S1-S2. Metastatic events in preclinical models of PDA (S1); Warfarin enhances the activity of gemcitabine in an Axl-dependent manner (S2).
Appendix from Meeting Report: Inaugural Chemotherapy-Induced Peripheral Neuropathy Symposium, Santa Barbara, CA, February 2015
Authors: Smith Jennifer A. , Benbow Sarah J.
Published: March 2023

Appendix. Organizer and speaker names and affiliations
Supplemental Figure 5 from CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Authors: Hu Shanhu , Danilov Alexey V. , Godek Kristina , Orr Bernardo , Tafe Laura J. , Rodriguez-Canales Jaime , Behrens Carmen , Mino Barbara , Moran Cesar A. , Memoli Vincent A. , Mustachio Lisa Maria , Galimberti Fabrizio , Ravi Saranya , DeCastro Andrew , Lu Yun , Sekula David , Andrew Angeline S. , Wistuba Ignacio I. , Freemantle Sarah , Compton Duane A. , Dmitrovsky Ethan
Published: March 2023

Supplemental Fig. S5. Representative CP110 immunohistochemistry staining of lung normal (N) versus malignant (T) tissues harvested independently from KRAS wild-type transgenic mice and KRAS mutant transgenic mice.The table displays KRAS mutation information, CP110 scoring and intensity of CP110 immunostaining in 6 lung cancer specimens from cyclin-E transgenic mice and Kras LSL-G12D driven engineered mice respectively.
Supplemental Figure 2 from CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Authors: Hu Shanhu , Danilov Alexey V. , Godek Kristina , Orr Bernardo , Tafe Laura J. , Rodriguez-Canales Jaime , Behrens Carmen , Mino Barbara , Moran Cesar A. , Memoli Vincent A. , Mustachio Lisa Maria , Galimberti Fabrizio , Ravi Saranya , DeCastro Andrew , Lu Yun , Sekula David , Andrew Angeline S. , Wistuba Ignacio I. , Freemantle Sarah , Compton Duane A. , Dmitrovsky Ethan
Published: March 2023

Supplemental Fig. S2. Overexpression of wild-type CP110, but not phosphorylation-sites mutated CP110 in LKR13 murine lung cancer cells that are driven by KRAS rescued anaphase catastrophe and reduced apoptosis induced by pharmacological CDK2 inhibition after seliciclib treatment. LKR13 cells overexpressing wild-type CP110 species or an empty vector, a phosphorylation-sites mutant-CP110 species (MUT-CP110) or an empty vector (Vector) were treated with indicated dosages of seliciclib. After 24 hours treatment, LKR13 cells were (A) scored for multipolar anaphase and (B) analyzed for apoptosis, as detected by Annexin V:FITC and 7-aminoactinomycin D (7-AAD) staining.
Supplementary Figure S2 from Tropomodulin 1 Expression Driven by NF-κB Enhances Breast Cancer Growth
Authors: Ito-Kureha Taku , Koshikawa Naohiko , Yamamoto Mizuki , Semba Kentaro , Yamaguchi Noritaka , Yamamoto Tadashi , Seiki Motoharu , Inoue Jun-ichiro
Published: March 2023

Supplementary Figure S2. TMOD1 overexpression enhanced proliferation of MDA-MB-436 and BT-549 cells in the type I collagen-mediated 3D culture but not in conventional 2D culture.
Supplemental Tables and Figures. from Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung
Authors: Leng Shuguang , Wu Guodong , Collins Leonard B. , Thomas Cynthia L. , Tellez Carmen S. , Jauregui Andrew R. , Picchi Maria A. , Zhang Xiequn , Juri Daniel E. , Desai Dhimant , Amin Shantu G. , Crowell Richard E. , Stidley Christine A. , Liu Yushi , Swenberg James A. , Lin Yong , Wathelet Marc G. , Gilliland Frank D. , Belinsky Steven A.
Published: March 2023

Supplementary Table 1. Characteristics of study subjects in LSC and VSC Supplementary Table 2. Common SNPs associated with risk for MGMT methylation in LSC GWAS discovery with p<10-5 in models with or without adjustment for rs16906252 Supplementary Table 3. Covariates included for adjustment in GLM. Supplementary Table 4. Delta changes for AUC ROC in logistic regressions with MGMT methylation as the outcome.Supplementary Table 5. The joint effect of the cis- (rs16906252) and trans- (rs16957091) acting SNPs on the risk for MGMT methylation in LSC and VSC Supplementary Figure 1. Quantile-quantile plots for GWAS discovery results in LSC. Supplementary Figure 2. Manhattan plot for genome-wide association in the LSC discovery set. Supplementary Figure 3. The enrichment of SNPs in ENCODE-annotated regulatory regions within the 472-kb haplotype block at chromosome 15q15.2 locus using data from small airway epithelial cells (SAEC).
Supplementary Table S2 from Neuroendocrine Transdifferentiation in Human Prostate Cancer Cells: An Integrated Approach
Authors: Cerasuolo Marianna , Paris Debora , Iannotti Fabio A. , Melck Dominique , Verde Roberta , Mazzarella Enrico , Motta Andrea , Ligresti Alessia
Published: March 2023

Supplementary Table S2. Parameter values used in the numerical simulations.
Supplementary Materials from Breast Cancer Detection by B7-H3–Targeted Ultrasound Molecular Imaging
Authors: Bachawal Sunitha V. , Jensen Kristin C. , Wilson Katheryne E. , Tian Lu , Lutz Amelie M. , Willmann Jürgen K.
Published: March 2023

Supplementary Table 1. Summary of B7-H3 Immunohistochemistry Scores in Human Tissue Samples. Supplementary Table 2. Subanalysis of B7-H3 IHC Scores in Cancer and Surrounding Normal, Benign and Precursor Lesions
Supplementary Materials and Methods from Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth
Authors: Rigoni Alice , Bongiovanni Lucia , Burocchi Alessia , Sangaletti Sabina , Danelli Luca , Guarnotta Carla , Lewis Amy , Rizzo Aroldo , Silver Andrew R. , Tripodo Claudio , Colombo Mario P.
Published: March 2023

Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Supplementary Figures S1-S5 from Mast Cells Infiltrating Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor Growth
Authors: Rigoni Alice , Bongiovanni Lucia , Burocchi Alessia , Sangaletti Sabina , Danelli Luca , Guarnotta Carla , Lewis Amy , Rizzo Aroldo , Silver Andrew R. , Tripodo Claudio , Colombo Mario P.
Published: March 2023

Supplementary Figures S1-S5. Colon length in wild-type and KitW-sh mice during colitis progression (S1); Il22 and Il22bp relative expression in colon in wild-type and KitW-sh mice (S2); Polyps count in colon of WT and KitW-sh mice (S3); Colorectal cancer development in WT, KitW-sh and KitW-sh REC mice (S4); Summary of MC activity in intestinal mucosal healing and in transformation toward malignancy (S5).
Supplementary Video S2 from Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery
Authors: Erickson-Bhatt Sarah J. , Nolan Ryan M. , Shemonski Nathan D. , Adie Steven G. , Putney Jeffrey , Darga Donald , McCormick Daniel T. , Cittadine Andrew J. , Zysk Adam M. , Marjanovic Marina , Chaney Eric J. , Monroy Guillermo L. , South Fredrick A. , Cradock Kimberly A. , Liu Z. George , Sundaram Magesh , Ray Partha S. , Boppart Stephen A.
Published: March 2023

Negative surgical margin. Video OCT cross-sectional images of a negative tumor margin from the in vivo resection bed of a 72 year-old female WLE patient with invasive ductal carcinoma as the surgeon sweeps the handheld probe along the margin.
Supplementary Table S4. from Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models
Authors: MacLeod A. Kenneth , McLaughlin Lesley A. , Henderson Colin J. , Wolf C. Roland
Published: March 2023

PK parameters of vemurafenib in huPXR/huCAR/huCYP3A4/3A7 and huPXR/huCAR mice pre-treated with RIF.
Supplementary tables 1-4 and figures 1-4 from NHANES 2009–2012 Findings: Association of Sexual Behaviors with Higher Prevalence of Oral Oncogenic Human Papillomavirus Infections in U.S. Men
Authors: Chaturvedi Anil K. , Graubard Barry I. , Broutian Tatevik , Pickard Robert K.L. , Tong Zhen-yue , Xiao Weihong , Kahle Lisa , Gillison Maura L.
Published: March 2023

Supplementary tables 1-4 and figures 1-4: Table 1: Comparison of non-participants/non-responders versus participants/responders for the oral HPV protocol of NHANES 2009-2012. Table 2: Comparison of oral HPV prevalence between NHANES 2009-2010 and NHANES 2011-2012. Table 3: Prevalence of oral oncogenic HPV infection and unadjusted prevalence differences by demographic and behavioral characteristics among men and women in the U.S., NHANES 2009-2012. Table 4: Adjusted associations of demographic and behavioral factors with HPV prevalence for 12 oncogenic HPV types among men and women in the U.S. population, NHANES 2009-2012. Figure 1: Adjusted association of age with oral oncogenic HPV prevalence among men and women in the U.S., NHANES 2009-2012. Figure 2: Prevalence of oral oncogenic HPV among men and women in the U.S. (NHANES 2009-2012) using a revised classification for oncogenic types. Figure 3: Burden of 12 oral oncogenic HPV infection among men in the U.S. population, NHANES 2009-2012. Figure 4: Burden of 12 oral oncogenic HPV infection among women in the U.S. population, NHANES 2009-2012.
Supplementary Figure 1 from Tumor-Induced Pressure in the Bone Microenvironment Causes Osteocytes to Promote the Growth of Prostate Cancer Bone Metastases
Authors: Sottnik Joseph L. , Dai Jinlu , Zhang Honglai , Campbell Brittany , Keller Evan T.
Published: March 2023

Supplemental Figure 1: PC3 growth in bone does not increase ImP. PC3 tumor cells were injected into SCID mice 24 hours prior to implant with a wireless pressure monitoring device. A) A small increase in ImP during week 2 was observed, but was not statistically significant. B) Significant bone lysis due to tumor growth was observed. Tumor induced bone lysis may be a mechanism for relieving the pressure associated with more osteoblastic PCa tumors such as ACE1 and DU145.
Supplemental Table 1 from Tumor-Induced Pressure in the Bone Microenvironment Causes Osteocytes to Promote the Growth of Prostate Cancer Bone Metastases
Authors: Sottnik Joseph L. , Dai Jinlu , Zhang Honglai , Campbell Brittany , Keller Evan T.
Published: March 2023

Supplementary Table 1: Pressurized MLO-Y4 secretes numerous cytokines and chemokines. CM was pressurized at 40 mmHg and compared to 0 mmHg CM by commercially available cytokine array. Table of relative densitometry values normalized to 0 mmHg CM.
Supplementary Table S1 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: March 2023

Supplementary Table S1. Parameter estimates and interindividual variability for the (â€�)â€�Nutlinâ€�3 pharmacokinetic model.
Supplementary Figure S1 from Mdm2 and Aurora Kinase A Inhibitors Synergize to Block Melanoma Growth by Driving Apoptosis and Immune Clearance of Tumor Cells
Authors: Vilgelm Anna E. , Pawlikowski Jeff S. , Liu Yan , Hawkins Oriana E. , Davis Tyler A. , Smith Jessica , Weller Kevin P. , Horton Linda W. , McClain Colt M. , Ayers Gregory D. , Turner David C. , Essaka David C. , Stewart Clinton F. , Sosman Jeffrey A. , Kelley Mark C. , Ecsedy Jeffrey A. , Johnston Jeffrey N. , Richmond Ann
Published: March 2023

Supplementary Figure S1. The hybrid physiologically-based pharmacokinetic models for (-)-Nutlin-3 and MLN8237 comprising several organ compartments.
Supplementary Table 1 from Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function
Authors: Rajeshkumar N.V. , Dutta Prasanta , Yabuuchi Shinichi , de Wilde Roeland F. , Martinez Gary V. , Le Anne , Kamphorst Jurre J. , Rabinowitz Joshua D. , Jain Sanjay K. , Hidalgo Manuel , Dang Chi V. , Gillies Robert J. , Maitra Anirban
Published: March 2023

Supplementary Table 1. Mutational status of PDXs.
Supplementary Table S6: Mass spectrometry lipidomics / metabolomics data from Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids
Authors: Southam Andrew D. , Khanim Farhat L. , Hayden Rachel E. , Constantinou Julia K. , Koczula Katarzyna M. , Michell Robert H. , Viant Mark R. , Drayson Mark T. , Bunce Chris M.
Published: March 2023

Mass spectrometry data: glycerol 3-phosphate and glycerolipids
Supplementary Methods from Leptin–STAT3–G9a Signaling Promotes Obesity-Mediated Breast Cancer Progression
Authors: Chang Chao-Ching , Wu Meng-Ju , Yang Jer-Yen , Camarillo Ignacio G. , Chang Chun-Ju
Published: March 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Suppl Table S5 from Differentiation and Loss of Malignant Character of Spontaneous Pulmonary Metastases in Patient-Derived Breast Cancer Models
Authors: Bockhorn Jessica , Prat Aleix , Chang Ya-Fang , Liu Xia , Huang Simo , Shang Meng , Nwachukwu Chika , Gomez-Vega Maria J. , Harrell J. Chuck , Olopade Olufunmilayo I. , Perou Charles M. , Liu Huiping
Published: March 2023

Suppl Table S5. Genes regulated by miR-138
Supplementary figure 2 from Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Authors: Mansour Nassir M. , Bernal Giovanna M. , Wu Longtao , Crawley Clayton D. , Cahill Kirk E. , Voce David J. , Balyasnikova Irina V. , Zhang Wei , Spretz Ruben , Nunez Luis , Larsen Gustavo F. , Weichselbaum Ralph R. , Yamini Bakhtiar
Published: March 2023

Supplementary figure 2. A, ChIP using DCR1 promoter specific primers. Quantitative data show chromatin enrichment of Bcl3 relative to input after controlling for non-specific binding using anti-histone H1 (positive control) and anti-IgG, normalized to vehicle treatment, {plus minus} SD of 3 triplicate samples repeated. Semi-quantitative blot of the PCR product from the p50 and Bcl3 ChIP experiments are shown (right). B, immunoblot with anti-DcR1 or anti-Bcl3 in U87 cells transfected with empty vector (EV) or Bcl3 and treated with 100 μM TMZ for the indicated time. C, qPCR analysis of DCR1 mRNA expression in U87 clones expressing the indicated sh-DcR1 or sh-control construct. Data show mean DCR1 transcript expression relative to GAPDH, {plus minus}SD of triplicate samples. D, trypan blue dye exclusion in sh-cntl and sh-DcR1-3 cells following treatment with vehicle or 100 μM TMZ for the indicated times. Data show mean % cell death, {plus minus} SD of triplicate samples. *, P < 0.05. **, P < 0.01.
Supplementary Materials and Methods from Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells
Authors: Lo Albert , Wang Liang-Chuan S. , Scholler John , Monslow James , Avery Diana , Newick Kheng , O'Brien Shaun , Evans Rebecca A. , Bajor David J. , Clendenin Cynthia , Durham Amy C. , Buza Elizabeth L. , Vonderheide Robert H. , June Carl H. , Albelda Steven M. , Puré Ellen
Published: March 2023

Supplementary materials and methods.
Supplementary Fig. S2 from Development of Lung Adenocarcinomas with Exclusive Dependence on Oncogene Fusions
Authors: Saito Motonobu , Shimada Yoko , Shiraishi Kouya , Sakamoto Hiromi , Tsuta Koji , Totsuka Hirohiko , Chiku Suenori , Ichikawa Hitoshi , Kato Mamoru , Watanabe Shun-ichi , Yoshida Teruhiko , Yokota Jun , Kohno Takashi
Published: March 2023

Supplementary Fig. S2. Gene mutation numbers by driver gene status
Supplementary Fig. S1 from Development of Lung Adenocarcinomas with Exclusive Dependence on Oncogene Fusions
Authors: Saito Motonobu , Shimada Yoko , Shiraishi Kouya , Sakamoto Hiromi , Tsuta Koji , Totsuka Hirohiko , Chiku Suenori , Ichikawa Hitoshi , Kato Mamoru , Watanabe Shun-ichi , Yoshida Teruhiko , Yokota Jun , Kohno Takashi
Published: March 2023

Supplementary Fig. S1. Sequencing depth and estimated tumor content
Supplementary Figure 5 from Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells
Authors: Lo Albert , Wang Liang-Chuan S. , Scholler John , Monslow James , Avery Diana , Newick Kheng , O'Brien Shaun , Evans Rebecca A. , Bajor David J. , Clendenin Cynthia , Durham Amy C. , Buza Elizabeth L. , Vonderheide Robert H. , June Carl H. , Albelda Steven M. , Puré Ellen
Published: March 2023

Analysis of immune infiltrating cells in 4662 tumors following FAP-CAR Therapy.
Supplementary Table S8 from Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
Authors: Gámez-Pozo Angelo , Berges-Soria Julia , Arevalillo Jorge M. , Nanni Paolo , López-Vacas Rocío , Navarro Hilario , Grossmann Jonas , Castaneda Carlos A. , Main Paloma , Díaz-Almirón Mariana , Espinosa Enrique , Ciruelos Eva , Fresno Vara Juan Ángel
Published: March 2023

Supplementary Table S8. Description of the functional nodes identified in the probabilistic graphical models analyses.
Supplementary Table S7 from Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
Authors: Gámez-Pozo Angelo , Berges-Soria Julia , Arevalillo Jorge M. , Nanni Paolo , López-Vacas Rocío , Navarro Hilario , Grossmann Jonas , Castaneda Carlos A. , Main Paloma , Díaz-Almirón Mariana , Espinosa Enrique , Ciruelos Eva , Fresno Vara Juan Ángel
Published: March 2023

Supplementary Table S7. List of microRNAs differentially expressed between ER+ and TNBC samples.
Supplementary Figure 1 from Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells
Authors: Lo Albert , Wang Liang-Chuan S. , Scholler John , Monslow James , Avery Diana , Newick Kheng , O'Brien Shaun , Evans Rebecca A. , Bajor David J. , Clendenin Cynthia , Durham Amy C. , Buza Elizabeth L. , Vonderheide Robert H. , June Carl H. , Albelda Steven M. , Puré Ellen
Published: March 2023

Identification of FAP+ cancer-associated stromal cells in desmoplastic A549 tumors.
Supplementary Table S4 from Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
Authors: Gámez-Pozo Angelo , Berges-Soria Julia , Arevalillo Jorge M. , Nanni Paolo , López-Vacas Rocío , Navarro Hilario , Grossmann Jonas , Castaneda Carlos A. , Main Paloma , Díaz-Almirón Mariana , Espinosa Enrique , Ciruelos Eva , Fresno Vara Juan Ángel
Published: March 2023

Supplementary Table S4. Gene ontology analyses from differential proteins between ER+ and TNBC.
Supplementary Table S3 from Combined Label-Free Quantitative Proteomics and microRNA Expression Analysis of Breast Cancer Unravel Molecular Differences with Clinical Implications
Authors: Gámez-Pozo Angelo , Berges-Soria Julia , Arevalillo Jorge M. , Nanni Paolo , López-Vacas Rocío , Navarro Hilario , Grossmann Jonas , Castaneda Carlos A. , Main Paloma , Díaz-Almirón Mariana , Espinosa Enrique , Ciruelos Eva , Fresno Vara Juan Ángel
Published: March 2023

Supplementary Table S3. List of proteins differentially expressed between ER+ and TNBC samples.
Supplementary Table 1 from TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis
Authors: Shai Anny , Dankort David , Juan Joseph , Green Shon , McMahon Martin
Published: March 2023

Diminished frequency of adenocarcinoma formation with increased time between recombination events.
Supplementary Figure 1 from TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis
Authors: Shai Anny , Dankort David , Juan Joseph , Green Shon , McMahon Martin
Published: March 2023

Temporal activation of the p53R270H cooperates with BRAFV600E to form lung adenocarcinomas.
Supplementary Table S2 from PLK1 Phosphorylates PAX3-FOXO1, the Inhibition of Which Triggers Regression of Alveolar Rhabdomyosarcoma
Authors: Thalhammer Verena , Lopez-Garcia Laura A. , Herrero-Martin David , Hecker Regina , Laubscher Dominik , Gierisch Maria E. , Wachtel Marco , Bode Peter , Nanni Paolo , Blank Bernd , Koscielniak Ewa , Schäfer Beat W.
Published: March 2023

Supplementary Table S2. Small-molecule library.
Supplementary Figures S1-S7, Materials and Methods from FoxM1 Drives a Feed-Forward STAT3-Activation Signaling Loop That Promotes the Self-Renewal and Tumorigenicity of Glioblastoma Stem-like Cells
Authors: Gong Ai-hua , Wei Ping , Zhang Sicong , Yao Jun , Yuan Ying , Zhou Ai-dong , Lang Frederick F. , Heimberger Amy B. , Rao Ganesh , Huang Suyun
Published: March 2023

Supplementary Figures S1-S7 - Supplementary Figures S1-7 and Figure Legends. Supplementary Figure S1. FoxM1 regulates PDGF-A in GSCs and NSCs. Supplementary Figure S2. FoxM1 directly interacts with the PDGF-A promoter and regulates its activation. Supplementary Figure S3. FoxM1 maintains the stemness of GSCs partially via PDGF-A. Supplementary Figure S4. FoxM1 inhibition decreases cell proliferation and increases the chemosensitivity of GSCs to TMZ. Supplementary Figure S5. STAT3C reinstates self-renewal and tumor growth of GSCs with depleted FoxM1. Supplementary Figure S6. FoxM1 reprograms glioma cells to GSC-like cells. Supplementary Figure S7. FoxM1 promotes glioma cells reprogramming to GSC-like cells via STAT3. Supplemental Materials and Methods- Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Supplementary Figure Legends from PLK1 Phosphorylates PAX3-FOXO1, the Inhibition of Which Triggers Regression of Alveolar Rhabdomyosarcoma
Authors: Thalhammer Verena , Lopez-Garcia Laura A. , Herrero-Martin David , Hecker Regina , Laubscher Dominik , Gierisch Maria E. , Wachtel Marco , Bode Peter , Nanni Paolo , Blank Bernd , Koscielniak Ewa , Schäfer Beat W.
Published: March 2023

Supplementary Figure Legends. Legend for Supplementary Figures S1-S7.
Supplementary Tables S1-S7 from Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling
Authors: Hultberg Anna , Morello Virginia , Huyghe Leander , De Jonge Natalie , Blanchetot Christophe , Hanssens Valérie , De Boeck Gitte , Silence Karen , Festjens Els , Heukers Raimond , Roux Benjamin , Lamballe Fabienne , Ginestier Christophe , Charafe-Jauffret Emmanuelle , Maina Flavio , Brouckaert Peter , Saunders Michael , Thibault Alain , Dreier Torsten , de Haard Hans , Michieli Paolo
Published: March 2023

Supplementary Tables S1-S7. Binding of WT52, WT52-E and WT52-D to human and mouse Fc gamma receptors (S1); ADCC activity of engineered antibodies (S2); In vitro characterization of the germlined G52 antibody (S3); Binding of G52 and ARGX-111 to human, mouse and simian Fc receptors (S4); ARGX-111 displays dose-dependent binding to MET-expressing human cell lines (S5); ARGX-111 promotes ADCC of MET-expressing human tumor cell lines (S6); Mammary carcinoma stem cells express MET (S7).
Supplementary Methods and References from Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling
Authors: Hultberg Anna , Morello Virginia , Huyghe Leander , De Jonge Natalie , Blanchetot Christophe , Hanssens Valérie , De Boeck Gitte , Silence Karen , Festjens Els , Heukers Raimond , Roux Benjamin , Lamballe Fabienne , Ginestier Christophe , Charafe-Jauffret Emmanuelle , Maina Flavio , Brouckaert Peter , Saunders Michael , Thibault Alain , Dreier Torsten , de Haard Hans , Michieli Paolo
Published: March 2023

Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.