bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating the efficiency of the synergistic effect in the business network
Authors: Dykan Valeriia , Pakharenko Oleksandr , Saienko Volodymyr , Skomorovskyi Andrii , Neskuba Tetiana
Published: March 2021

The article aimed to develop a methodology for monitoring the quality level of the synergistic effect of enterprises' economic activity in business network interaction on the example of mechanical engineering in Ukraine. Using the expert assessments of 386 senior and middle managers of 27 mechanical engineering enterprises of the Kharkiv region and the main components' method, the components of qualitative parameters of the synergetic effect of economic activity result from network interaction have been determined. An additive econometric model has been developed to calculate the integrated indicator of enterprises' economic activity's synergetic effect in terms of the business network of the studied enterprises. Using Fibonacci rules, the levels of qualitative component components and the integrated indicator of the synergy of economic activity in the context of a single network partner are determined.
Shear wave elastography detects novel imaging biomarkers of aromatase inhibitor–induced joint pain: a pilot study
Authors:   The University of Arizona Cancer Center, Tucson, AZ, USA, Martinez Jessica A. ,   Department of Nutritional Sciences, University of Arizona, Tucson, AZ, USA, Taljanovic Mihra S. ,   Department of Medical Imaging, University of Arizona, Tucson, AZ, USA,   Department of Orthopaedic Surgery, University of Arizona, Tucson, AZ, USA, Witte Russell S. ,   The University of Arizona Cancer Center, Tucson, AZ, USA,   Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA, Nuncio Zuniga Andres A. ,   Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA, Wertheim Betsy C. ,   The University of Arizona Cancer Center, Tucson, AZ, USA, Kwoh C. Kent ,   Department of Medical Imaging, University of Arizona, Tucson, AZ, USA,   The University of Arizona Arthritis Center, Tucson, AZ, USA,   Department of Medicine, University of Arizona, Tucson, AZ, USA, Goldstein Brian A. ,   Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA, Roe Denise J. ,   The University of Arizona Cancer Center, Tucson, AZ, USA,   Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, USA, Chalasani Pavani ,   The University of Arizona Cancer Center, Tucson, AZ, USA,   Department of Medicine, University of Arizona, Tucson, AZ, USA
Published: March 2021

Aim: To determine whether differences in joint and tendon stiffness as measured by ultrasound shear wave elastography are present in breast cancer patients with aromatase inhibitor- associated arthralgias compared to age-comparable healthy control women. Methods: Postmenopausal women with stage I–III breast cancer who were taking adjuvant aromatase inhibitors and complained of joint pain were enrolled (n = 6). Postmenopausal women with no history of breast cancer, hormone treatment, or joint pain served as controls (n = 7). All subjects had bilateral hands and wrists evaluated by gray-scale and power Doppler ultrasound, and shear wave elastography ultrasound. Results: Patients with AI-associated arthralgias had significantly stiffer tendons than controls in the 1st extensor compartment (long axis; p = 0.001), 4th extensor compartment (long axis; p = 0.014), 3rd metacarpophalangeal joint (p = 0.002), the pooled values of the extensor compartments, both long (p = 0.044) and short axes (p = 0.035), and the pooled values for the metacarpophalangeal joints (p = 0.002). On ultrasound, the patients (but not controls) presented with hyperemia and increased tenosynovial fluid in the flexor and extensor tendon sheaths, and the median nerves were symptomatic and bifid; however, these differences were not statistically significant. Conclusions: This is the first study to identify increased tendon stiffness as a putative physiological characteristic of aromatase inhibitor–associated arthralgias. Future studies should determine whether increased tendon stiffness is a risk factor for the development of aromatase inhibitor–associated arthralgias, or a result of aromatase inhibitor treatment.
Delayed Bleeding in a Hemophilic Patient After Sinus Floor Elevation and Multiple Implant Placements: A Case Report
Authors: de Azevedo Kinalski Mateus , Brondani Lucas Pradebon , de Mattos Carpena Augusto Luis Mendes , dos Santos Mateus Bertolini Fernandes
Published: March 2021

Dental treatments in hemophilic patients are challenging, and the absence of adequate preparation for the procedures can be life-threatening. This letter describes a delayed postoperative bleeding after multiple dental implants with sinus floor elevation in a patient with mild hemophilia A.
The Determining Factors in the Development of Jurisdictions: The Evolution of Legal Policy and Legal Culture
Authors: Inshakova Agnessa
Published: March 2021

The paper is devoted to substantiating the relevance, scientific and practical significance of the problematics “The Evolution of legal policy and legal culture: territorial and scientific and technological factors of the development of jurisdictions” covered in the section “The Main Topic of the Issue” of the legal journal of Volgograd State University “Legal Concept = Pravovaya paradigma”. The author substantiates as one of the leading prerequisites for the transformation of the legal policy and legal culture of states such factors in the development of modern reality as the creation of integration associations and unions, which entail the convergence of national jurisdictions, as well as scientific and technological modernization of all spheres of public life as a result of the fourth industrial revolution and neoindustrialization of the economy. The author argues for the powerful influence of these promising trends of socio-economic transformations on the legal and law-making policy of the state, as well as on the legal morality, legal awareness and legal culture in general “imposed” by the lawmakers and law enforcement officers within the territory of the national jurisdiction. The paper considers the integral components that accompany the fourth industrial revolution and determine the overall impact of scientific and technological development on the fundamental categories of the legal system under consideration. On the example of specific territorial associations of the member states of the integration unions of the EU, EAEU, BRICS, MERCOSUR, and SCO, the processes of creating common legal spaces that erase differences in approaches to the formation of legal policy and legal culture of sovereign limited jurisdictions are described. A brief description of the papers presented in the main topic of the issue, reflecting the historical patterns and current trends in scientific, technological and integration development that affect the transformation of legal policy and legal culture, is given.
The Concept and Civil Aspects of Cultural Activities in the Russian Federation
Authors: Sevostyanov Maxim
Published: March 2021

Introduction: cultural activities are important in the lives of people at all stages of human development without exception. At present, culture as the basis of the activity under consideration is the subject of research in many humanities and other sciences. However, this activity also has private law properties that are in many cases identical to the system elements of civil law. The purpose of the publication is to identify these properties that affect the legal nature of cultural activities. Methods: the research is based on the system method, civilized techniques and the methods of interpretation, the methods of analysis and synthesis, and the comparative legal method. Results: the paper substantiates the author’s view of cultural activity as a system of actions of the civil turnover participants aimed at creating, transforming, preserving, distributing and applying cultural values in the sphere of spiritual and material needs of a person. The studied activity is characterized by the subject elements of the civil law branch, which are manifested in the legal nature of the participants, the dynamics of ownership of the cultural objects, the contractual regulation of “cultural” relations, and the means of protecting cultural rights. Conclusions: in the course of the research, the author identifies the qualifying features of the cultural activity, united by the dynamics of cultural values in the context of improving the spiritual and material needs of people. The essence of civil law aspects inherent in cultural activities at the present stage of civil turnover development is determined and argued. The systemic nature of the fundamental, subject, object, real-law, contractual, intellectual, protective and other private-law aspects allows us to qualify cultural activities as a process of exercising civil rights.
Agreements to Eliminate Liability for Breach of a Contractual Obligation: Comparative Analysis of the Legal Regulation and Judicial Practice
Authors: Kagalnitskova Natalia , Tolstova Olga
Published: March 2021

Introduction: modern legal science is faced with the task of developing the concept of an agreement on the elimination of contractual civil liability: determining its legal nature, scope and conditions for its implementation. For this purpose, the authors of the paper attempt to model the theoretical and legal basis of the agreement on the elimination of contractual liability of the debtor for non-performance, improper performance of its obligations. Using the general scientific methods – synthesis, analysis, comparative and dialectical methods, as well as the specific scientific methods of cognition, in particular, formal-legal, structural-functional and others, the authors determine the legal nature and scope of the agreement on the elimination of contractual liability for violation of a contractual obligation, and examine the practice of such application. Results: it is indicated that within the framework of the agreement on the elimination of contractual liability, it is possible to expand the list of circumstances related to “force majeure”, but taking into account the criterion of the latter: emergency and insurmountability. Conclusions: an agreement to eliminate contractual liability is not possible in contractual obligations involving a weak party, unless it is concluded in its favor. Therefore, the main scope of their application is the obligations related to the implementation of business activities. The possibility of concluding this agreement is a manifestation of the principles of autonomy of will and freedom of contract.
Constrained Multiagent Markov Decision Processes: a Taxonomy of Problems and Algorithms
Authors: De Nijs Frits , Walraven Erwin , De Weerdt Mathijs , Spaan Matthijs
Published: March 2021

In domains such as electric vehicle charging, smart distribution grids and autonomous warehouses, multiple agents share the same resources. When planning the use of these resources, agents need to deal with the uncertainty in these domains. Although several models and algorithms for such constrained multiagent planning problems under uncertainty have been proposed in the literature, it remains unclear when which algorithm can be applied. In this survey we conceptualize these domains and establish a generic problem class based on Markov decision processes. We identify and compare the conditions under which algorithms from the planning literature for problems in this class can be applied: whether constraints are soft or hard, whether agents are continuously connected, whether the domain is fully observable, whether a constraint is momentarily (instantaneous) or on a budget, and whether the constraint is on a single resource or on multiple. Further we discuss the advantages and disadvantages of these algorithms. We conclude by identifying open problems that are directly related to the conceptualized domains, as well as in adjacent research areas.
Relating physical properties to temperature-induced damage in carbonate rocks
Authors: Vagnon F. , Colombero C. , Comina C. , Ferrero A. M. , Mandrone G. , Missagia R. , Vinciguerra S. C.
Published: March 2021

Carbonate rocks have a widespread diffusion in the Earth crust and are extensively used in cultural heritage and buildings. These rocks can be naturally or anthropically exposed to high temperatures. Consequently, relating physical properties to temperature-induced damage is extremely important. Six sets of compositionally and texturally different carbonate rocks, spanning from limestones and marbles to dolomitic marbles, were analysed in this study. Different physical properties, such as porosity, seismic wave velocities and electrical resistivity, were measured before and after thermal treatments with heating/cooling ranges between 105 and 600°C. Microstructural observations and optical analyses were used to investigate how temperature-induced damage affects the physical measured properties of the different microstructures. This integrated approach allowed to define a generalised relationship between physical properties and thermal-induced damage, by way of an induced damage index valid for a broad suite of carbonate rocks.
Evaluation of the Antioxidant and Antimicrobial Activities of Ethyl Acetate Extract of Saccharomyces cerevisiae
Authors: Makky Essam A. , AlMatar Manaf , Mahmood Mahmood H. , Ting Ooi Wei , Qi Wong Zi
Published: March 2021

Research background. Antioxidants are important compounds present at low concentrations that inhibit oxidation processes. Due to the side effects of synthetic antioxidants, research interest has increased considerably towards finding natural sources of antioxidants that can replace the synthetic ones. The emergence and spread of antibiotic resistance require the development of new drugs or some potential sources of novel medicine. This work aims to extract the secondary metabolites of Saccharomyces cerevisiae using ethyl acetate as a solvent and to determine the antioxidant and antimicrobial activities of these extracted metabolites.

Experimental approach. The antioxidant activity of the secondary metabolites of S. cerevisiae were determined using DPPH, ABTS and FRAP assays. Furthermore, the antimicrobial potential of the ethyl acetate extract of S. cerevisiae against Cutibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis was assessed.

Results and conclusion. Five out of 13 of the extracted secondary metabolites were
identified as antioxidants. The antioxidant activity of the S. cerevisiae extract exhibited
relatively high IC50 of 455.26 and 294.51 μg/mL for DPPH and ABTS respectively, while the obtained FRAP value, expressed as ascorbic acid equivalents, was 44.40 μg/mL. Moreover, the extract had a significant antibacterial activity (p<0.05) against Staphylococcus aureus and Staphylococcus epidermidis at the concentrations of 100 and 200 mg/mL, respectively. However, no inhibitory effect was observed against Cutibacterium acnes as the extract was only effective against the bacterium at the concentrations of 300and 400 mg/mL (inhibition zones ranging from 9.0±0.0 to 9.3±0.6) respectively (p<0.05). Staphylococcus aureus was highly sensitive to the extract, with a MIC value of 18.75 mg/mL.

Novelty and scientific contribution. This report confirmed the efficacy of the secondary
metabolites of S. cerevisiae as a natural source of antioxidants and antimicrobials and suggested the possibility of employing them in drugs for the treatment of infectious diseases caused by the tested microorganisms.
The Irkutsk History of the State Bank of Russia
Authors:   Baikal State University, Roshupkina Elena
Published: March 2021

The article considers review of the N.I. Gavrilova’s and V.P. Shaherova’s monograph «The state bank in Irkutsk: from the Russian Empire to the present. To celebrate the 150th anniversary of the founding». The author analyzes the history of foudantion and development of Irkutsk department of the Bank of Russia on the basis of extensive archival material.
Connecting Through Technology During COVID-19
Authors: Hall Jeffrey , Pennington Natalie , Holmstrom Amanda
Published: March 2021

This manuscript examines the patterns of information communication technology (ICT) use with friends and family outside of the home during the COVID-19 pandemic, and the associations among ICT use and psychological (i.e., loneliness; stress) and social (i.e., social needs; relationship maintenance) wellbeing. In early May 2020, a representative panel of American adults was surveyed (N = 1,947). Results suggest that despite 90% of the sample complying with shelter-in-place (SIP) orders, face-to-face contact with friends and family outside of the home was the primary predictor of getting one’s social needs met and mitigating loneliness. In contrast with predictions drawn from media richness theory, voice calls were associated with less stress, loneliness, and relationship maintenance difficulties, while video chat was positively associated with all three. Moderation analyses suggested that other factors (i.e., SIP, age) influenced the strength of association between modalities (i.e., face-to-face, email, social media) and outcomes. The theoretical implications for MRT and the practical implications for mediated sociality during the early stages of the COVID-19 pandemic are discussed.
Helicase-like transcription factor-deletion from the tumor microenvironment in a cell line-derived xenograft model of colorectal cancer reprogrammed the human transcriptome-S-nitroso-proteome to promote inflammation and redirect metastasis v1
Authors: A Helmer Rebecca , Raul Martinez-Zaguilan not provided , Gurvinder Kaur not provided , Lisa A Smith not provided , Jannette M Dufour not provided , S Chilton Beverly
Published: March 2021

Methylation of the HLTF gene in colorectal cancer (CRC) cells occurs more frequently in men than women. Progressive epigenetic silencing of HLTF in tumor cells is accompanied by negligible expression in the tumor microenvironment (TME). Cell line-derived xenografts (CDX) were established in control (Hltf+/+) and Hltf-deleted male Rag2-/-IL2rg-/- mice by direct orthotopic cell microinjection (OCMI) of HLTF+/+HCT116 Red-FLuc cells into the submucosa of the cecum. Combinatorial induction of IL6 and S100A8/A9 in the Hltf-deleted TME with ICAM-1 and IL8 in the primary tumor activated a positive feedback loop. The proinflammatory niche produced a major shift in CDX metastasis to peritoneal dissemination compared to controls. Inducible nitric oxide (iNOS) gene expression and transactivation of the iNOS-S100A8/A9 signaling complex in Hltf-deleted TME reprogrammed the human S-nitroso-proteome. POTEE, TRIM52 and UN45B were S-nitrosylated on the conserved I/L-X-C-X2-D/E motif indicative of iNOS-S100A8/A9-mediated S-nitrosylation. 2D-DIGE and protein identification by MALDI-TOF/TOF mass spectrometry authenticated S-nitrosylation of 53 individual cysteines in half-site motifs (I/L-X-C or C-X-X-D/E) in CDX tumors. POTEE in CDX tumors is both a general S-nitrosylation target and an iNOS-S100A8/A9 site-specific (Cys638) target in the Hltf-deleted TME. REL is an example of convergence of transcriptomic-S-nitroso-proteomic signaling. The gene is transcriptionally activated in CDXtumors with an Hltf-deleted TME, and REL-SNO (Cys143) was found in primary CDX tumors and all metastatic sites. Primary CDX tumors from Hltf-deleted TME shared 60% of their S-nitroso-proteome with all metastatic sites. Forty percent of SNO-proteins from primary CDX tumors were variably expressed at metastatic sites. Global S-nitrosylation of proteins in pathways related to cytoskeleton and motility was strongly implicated in the metastatic dissemination of CDX tumors. Hltf-deletion from the TME played a major role in the pathogenesis of inflammation and linked protein S-nitrosylation in primary CDX tumors with spatiotemporal continuity in metastatic progression when the tumor cells expressed HLTF.
Improved method of processing the output parameters of the diesel locomotive engine for more efficient maintenance
Authors: Zvolenský Peter , Barta Dalibor , Grenčík Juraj , Droździel Paweł , Kašiar Ľubomír
Published: March 2021

Modernization of aged rolling stock is one of the possibilities to adapt it to the current
requirements for better environmental friendliness and economy of railway transport. However, some vehicle upgrades lead to new failures that were not observed in the original vehicles. The cause is the so-called “hybrid design”, built on a combination of original and selected new components. The aim of the work was to improve the situation with frequent failures and unavailability that occur on the modernized locomotive where a new diesel engine and new electronic control system was installed. Within the work, a simplified methodology for evaluating the outputs of diagnostic equipment was developped based on and applied to specific locomotive type and its diesel engine. The methodology resulted in a significant reduction of the time for assessing the condition of the vehicle’s diesel engine and more effective maintenance. The paper also presents other possibilities in the analysis of big data in the maintenance of rolling stock e.g. using fuzzy logic.
Analysis of Book-borrowing Network using Complex Network Analysis
Authors: TUNALI Volkan , TÜMER Candan
Published: March 2021

In this study, we analyzed the book-borrowing network that we constructed from the database of the libraries of Ardahan University by using complex network analysis techniques. After the construction of the bipartite reader-book relationship network, we constructed reader-reader and book-book networks via one-mode projection. We performed an exploratory complex network analysis on these networks using Cytoscape and Gephi tools. We found that both networks revealed scale-free and small-world network properties like most real-world networks from diverse origins and of diverse sizes. In addition, we identified the most central books in the book-book network using several centrality measures. We also performed community analysis and identified the communities embedded in the networks visually.
Properties investigation of polyester yarns with different cross-sections
Authors: TOYDEMİR Yasin , VATANSEVER BARAMOL Derman
Published: March 2021

In this work, the properties of polyester filaments with different cross-sectional shapes were investigated. Trilobal, flat and hollow shaped polyester filaments, having the same count, were produced by following the same route and production parameters. Properties, such as tensile strength, elongation, breaking load, unevenness etc., were investigated. Comparative evaluations of the test results with regard to the cross-sectional shapes were carried out. The results showed that cross‐sectional shape of the filaments directly affected the yarn properties and trilobal filament containing polyester yarns showed better properties as compared to yarns containing filaments with a cross-sectional shape of hollow and flat.
The experience with the use of a subacromial balloon in the treatment of patients with large, massive, irreparable rotator cuff tears
Authors: Lazko Мaksim F. , Prizov Alexey P. , Lazko Fedor L. , Beliak Evgeny A. , Maglaperidze Ivan G. , Kyznetsov Aleksandr V. , Akhpashev Alexander A.
Published: March 2021

Background. Large, massive irreparable rotator cuff tears lead to a significant decrease in the function of the shoulder joint together with the development of a pronounced pain syndrome. Such injuries are difficult to treat, and the number of relapses, when trying to restore them, is quite high. The installation of a subacromial balloon is the method of choice for this group of patients and allows restoring the function of the shoulder joint fairly successfully. Aim: to evaluate the results of the treatment of patients with massive irreparable rotator cuff tears injuries in a prospective study from 2016 to 2018. Methods. The results of the arthroscopic treatment of large, irreparable rotator cuff injuries in 25 patients (with the average age of 67 5 years) with the installation of a subacromial balloon are presented. In all the clinical cases, there was a pronounced (grades 34, according to the Goutallier classification) fatty dystrophy of the rotator cuff muscles (supraspinatus or in combination with subaspinatus). All the patients underwent the subacromial space release with a thorough bursectomy and subsequent installation of a subacromial balloon. Results. The average score on the UCLA scale was 14 3 points (1117) before the operation and 312 points (2933) 12 months after the operation, the results were considered good and excellent. Conclusion. The results obtained allow us to evaluate the described technique as low-traumatic, simple and fast in its accomplishment, aimed at the reduction of the pain syndrome and restoration of the upper extremity function.
Diagnosis and treatment of iliac vein stenosis
Authors: Gitelzon Daniel G. , Faybushevich Alexander G. , Maximkin Daniel A. , Veretnik Galina I. , Baranovich Vladislav Yu. , Gitelzon Ekaterina А. , Sabirov Kirill R. , Vasilyev Alexander E. , Danishian Karen I.
Published: March 2021

Stenosis of the iliac veins is common in patients with chronic venous insufficiency. The article describes the methods for the diagnosis and treatment of iliac vein stenosis. The causes of iliac vein stenosis include extravasal compression or the consequences of ileofemoral thrombosis. Stenosis of the iliac veins exists in 1/4 of the entire adult population, but clinical manifestations do not occur in all patients. Stenosis of the iliac veins should be considered in case of an unknown edema, more often in the left lower extremity, since venous duplex ultrasound of lower extremities is not sensitive and specific enough when examining the veins above the inguinal ligament. The most accurate diagnostic method is intravascular ultrasound (IVUS) but the appeared computed tomography angiography (CTA) and magnetic resonance angiography (MRA) with high-quality images have become a good replacement for IVUS. The main method of treatment of iliac vein stenosis, besides stenting, isindispensable drug therapy consisting of antithrombotic and phlebotonic drugs.
Results of operative treatment of omphalocele with an additional lobe of the liver, and pyloric stenosis
Authors: Shchukina Anna A. , Mokrushina Olga G. , Gurskaya Alexandra S. , Dyakonova Elena Yu. , Akhmedova Dinara M.
Published: March 2021

Purpose. Presentation of clinical cases of rare combination of omphalocele with pylorostenosis in the postoperative period and additional liver lobe.
Materials and methods. In National Medical Research Center for Childrens Health of health surgical ward of newborns and infants for the 2019 us operated 2 children who performed surgery involving intra-operative decision making about further surgical tactics.
Results. the results of surgical treatment of newborns with omphalocele combined with hypertrophic pylorostenosis and extra liver lobe are presented.
Conclusions. In patients with malformations of the anterior abdominal wall in the postoperative period, when regurgitation syndrome appears, it is necessary to make a differential diagnosis between the functional and organic causes of obstruction. When confirming the organic nature of the obstruction, surgical intervention is indicated. It is necessary to be able to timely and objectively assess the risks and expediency of the approach when choosing surgical tactics in each individual case.
Unligature method of laparoscopic appendectomy in children
Authors: Svarich Vyacheslav G. , Perevozchikov Evgeniy G. , Kagantsov Ilya M.
Published: March 2021

Aim. On the basis of the accumulated clinical material to show the possibility of a ligature-free method of laparoscopic appendectomy in children.
Materials and methods. From 2000 to 2019, 2044 children with acute appendicitis were treated in the surgical department of the Republican childrens clinical hospital in Syktyvkar. Of these, 651 patients had an open appendectomy with treatment of the stump of the vermiform process by the submersible method, 1363 children had a laparoscopic appendectomy with ligature treatment of the stump of the process, and 32 patients had their first non-ligature laparoscopic appendectomy with the intersection of the vermiform process with the Ligasure device.
Results. On average, surgery for ligature-free laparoscopic appendectomy lasted 7 3 minutes less than for laparoscopic appendectomy using the ligature method for treating the stump of the worm-like process. Experimentally, it was found that this method of appendectomy should not be used when the thickness of the worm-like process is more than 1.5 cm, with pronounced inflammatory infiltration of the caecum dome and perforation at the base of the process. With ligature-free appendectomy, the operation time was reduced. In the period from 1 to 6 months, there were no intra-abdominal postoperative complications associated with the new method of surgery.
Conclusion. Ligar-free laparoscopic appendectomy in children using modern high-energy platforms with a digital assessment of the degree of tissue coagulation readiness made it possible to avoid intraoperative and postoperative complications, simplify the technique of its implementation, and reduce the time of surgery.
Gastric duplication cyst with localization in the pancreas in children
Authors: Sokolov Yurii Yu. , Efremenkov Artem M. , Zykin Aleksandr P. , Tumanova Elena L. , Omarova Zhanna R. , Antonov Dmitriy V. , Akhmatov Roman A.
Published: March 2021

Introduction. Gastric duplication cyst is a rare clinical observation. More often, these cysts are localized in the fundus or body of the stomach and have a common muscle layers and blood supply. Even more rarely, duplication cysts are not anatomically connected to the stomach and are located in other parts of the abdominal cavity or in the retroperitoneal space. Cystic duplication of the gastrointestinal tract, which are localized in the pancreas, is extremely rare.
The aim of the study is to demonstrate the possibility of using laparoscopy for this disease.
Materials and methods. The paper describes three rare clinical observations of gastric duplication cyst topographically associated with the pancreas. In the first clinical observation, gastric duplication cyst was combined with mediastinal duplication cysts, an esophageal bronchial fistula, and extralobar pulmonary sequestrations. In the second observation, a duplication cyst had communication with the pancreatic duct system and was clinically manifested by recurrent bleeding. In the third case, a duplication cyst is diagnosed behind the body and tail of the pancreas.
Results. In all cases, surgical treatment was carried out by the laparoscopic method, leading to complete recovery. Histological examination in all the described observations confirmed the gastric type of epithelium of the mucous membrane of the cysts. The article provides a review of the literature.
Conclusion. Thus, the efficiency of laparoscopic interventions in children with gastric duplications topographically associated with the pancreas was demonstrated. The described rare clinical manifestations, a combination of defects, as well as the possible presence of heterotopy of the mucous membrane of the duplication cyst confirm the need for surgical correction of the disease.
The effectiveness of volume guarantee ventilation in newborns
Authors: Ziganshin Il’dar M. , Bayalieva Ajnagul’ Zh. , Babintseva Anna A. , Shaimardanova Gul’nar R.
Published: March 2021

Background. An important goal of treating respiratory disorders in newborns during the first stage of perinatal care is effective and safe pulmonary ventilation, enabling the administration of surfactant therapy, reducing alveolar dead space, and providing adequate gas exchange.
Objective. The aim of this study is to improve the quality of newborns respiratory therapy using double pressure and volume control at the first stage of perinatal care.
Materials and methods. The study involved newborns from week 27 to week 42 gestation with respiratory failure requiring invasive pulmonary ventilation. The ventilation mode was evaluated with pressure control and volume guarantee option compared with routine pressure ventilation. For the comparative characteristic of the compared ventilation methods, we used targets, such as the duration of artificial pulmonary ventilation, reduction of FiO2, dynamics of venous blood lactate, peak and average pressure in the respiratory tract, dynamics of lung compliance, and the development of complications.
Results and conclusions. Given the heterogeneity of lung damage in newborns, the use of the guaranteed volume option reduced the duration of mechanical ventilation, the development frequency of IVH, and the frequency of surfactant use.
Endoscopic technologies in treatment 7-month-old child with multiple laryngeal cysts
Authors: Alkhasov Abdumanap B. , Dyakonova Elena Yu. , Lokhmatov Maxim M. , Rusetsky Yuri Yu. , Yatsyk Sergey P. , Romanova Ekaterina A. , Ratnikov Sergey A. , Komina Elena I.
Published: March 2021

Introduction. Subglottic cysts are a rare clinical entity among infants and children. The annual incidence of congenital laryngeal cysts is quoted as 1,82 per 100,000 live births. The majority of cases present in neonates born at the extremes of prematurity and invariably have been intubated and managed in neonatal intensive care units. Clinically, the pathology manifested as upper airway obstruction, stridor, and dysphonia. Various surgical techniques have been proposed for the treatment of patients with laryngeal cysts. In a large percentage of cases, tracheostomy is required, especially in patients with large cysts due to the development of symptoms of respiratory failure.
Purpose. The aim of this study is to demonstrate that endoscopic technologies in the treatment of laryngeal cysts in children can be useful to avoid tracheostomy and lead to an uneventful recovery.
Materials and methods. We present a clinical case of managing a 7-month-old child with multiple laryngeal cysts from the Department of Thoracic Surgery in the National Medical Research Center for Childrens Health Federal state autonomous institution of the Russian Federation Ministry of Health.
Conclusion. In the presented case, we demonstrate that modern minimally invasive techniques to treat laryngeal cysts restore the lumen of the respiratory tract. facilitate the course of the postoperative period, achieve complete patient recovery, and avoid tracheostomy.
Suprapatellar bursitis in a newborn
Authors: Erenkov IIya O. , Denisov Ivan S. , Zarubina Svetlana A.
Published: March 2021

Introduction. One of the most frequent pathologies in childhood is bursitis of the knee joint. Such conditions may occur in infectious pathologies, traumatic disorders, overuse syndromes, and other various pathologies. Diagnostic and treatment strategies depend on the cause of bursitis development. Particular attention should be paid to bursitis cases in newborns since the frequency of such pathologies is casuistic and clinical guidelines for treating patients in this age group are absent.
Materials and methods. A 26-day-old newborn arrived for consultation with complaints of knee joint pain and movement restrictions for four days. From five to 21 days of life, she has had in-patient treatment at another clinic because of pneumonia and a urinary tract infection. Intravenous and intramuscular injections of antibacterial drugs were prescribed for two weeks. The condition of the newborn was satisfactory upon consultation in our clinic. Her physical examination showed swelling and muscle tightness on the distal part of the thigh. The range of motion of the shinbone was restricted. Her blood test showed that her white cell count was unchanged. According to an X-ray examination of the knee, no pathology was detected. According to the US-examination, exudative suprapatellar bursitis was detected. The nonsteroidal anti-inflammatory drug, Nimesulid, was prescribed for seven days.
Results. Daily remote monitoring of the patient's well-being during treatment was performed. Movement restrictions reduced the swelling on day 3 of treatment. A follow-up blood test on day 4 of treatment showed no pathology. According to the follow-up US-examination after six days of drug therapy, no signs of bursitis were detected.
Conclusion. Inflammation of the suprapatellar bursa is a rare condition in newborns. In isolated cases of bursitis in children during the first year of life, a bacterial presence was noted, with the predominance of staphylococcal and streptococcal floras. However, in our opinion, there is a possibility of developing aseptic forms of bursitis in infants. In these cases, it may be prudent to refrain from prescribing courses of antibiotic therapy.
Influence of fluid overload in the post-operative period in newborns on the development of acute renal injury and duration of ICU stay
Authors: Zolotareva Lyubov’ S. , Khorev Vladimir V. , Makulova Anastasiya I. , Stepanenko Sergei M. , Zil’bert Elena V. , Svetlichnaya Tat’yana O.
Published: March 2021

Aim. To identify the relationship between fluid overload in children who received infusion therapy in the postoperative period at surgical intensive care unit (ICU), the development of acute kidney injury (AKI), and the length of ICU stay.
Methods. A retrospective cohort observational study was conducted. Our study includes 75 newborns with malformations of the gastrointestinal tract, diaphragmatic hernias, gastroschisis, necrotizing enterocolitis and sacrococcygeal teratomas treated after surgery in the ICU. The Kidney Disease: Improving Global Outcomes (nKDIGO) scale was used to detect AKI. To assess the fluid overload, the ratio of the difference between the introduced and released liquid and entering the ICU weight was used (in %). Significant overload was adopted value more than 5%. The indicator injected fluid consisted of the volume of infusion and enteral nutrition. The indicator of released fluid included diuresis, fluid loss from the gastrointestinal tract, intestinal stomas, and drainages.
Results. The frequency of AKI was 28.0% (21 of 75). The average time of AKI development from the moment of surgical intervention was 5.9 3.29 days. The duration of ICU stay after surgery was 8.0 [5.0; 16.0] days. In 18 of 75 (24%) children, the fluid overload of more than 5% was observed on the 1st postoperative day. In 12 out of 75 (16%) children, the fluid overload of more than 5% was observed on the 2nd postoperative day. A fluid overload of more than 5%, observed on the 1st day after the operation, was associated with a longer ICU stay. The rate of AKI is higher when a fluid overload of more than 5% on the 2nd day after surgery was observed.
Conclusion. Severe fluid overload can be a significant factor of the AKI development. Fluid overload more then 5% on the 2nd day after surgery may lead to an increase in the incidence of AKI. Liquid overload more then 5% on the 1st day after surgery may lead to an increase in the length of ICU stay. In newborns, it is necessary to take into account the fluid load at the first two days after the operation and correct the infusion therapy in case of fluid overload detection.
VI forum of children's surgeons of Russia with international participation
Authors: Gorbachyov Oleg S.
Published: March 2021

Information about the upcoming forum pediatric surgeons Russia, which will take place 2224 October 2020.
In memory of Sheraly R. Sultonov
Authors: Petlakh Vladimir I.
Published: March 2021

Information about the sudden death from Сovid-19, the head of the Department of Pediatric Surgery, Sherali R. Sultonov, the Republic of Tajikistan.
Ectopia of the pancreas in the loop of the small intestine in an 8-y-o child
Authors: Sharipov Aslamhon M. , Giesov Kholnazar A. , Zaripov Holmurod Z. , Sayfulloev Imatihudo D. , Sayfulloev Imatihudo D. , Guriev Kholid Ch. , Sodikov Nazir D.
Published: March 2021

Ectopia of the pancreas in children is a rare congenital malformation in which normal pancreatic tissue develops in other organs, without communication with the main gland in the wall of the stomach, intestines, liver, gallbladder, Meckel's diverticulum, and the spleen. In this article, the authors cite a rare case of ectopia of the pancreas in the loop of the small intestine, which led to the development of intestinal obstruction. Girl B., eight years old, was admitted to the hospital on an emergency basis with paroxysmal abdominal pain. There was no nausea or vomiting. A contrast study of the gastrointestinal tract with barium sulfate was performed, which revealed a violation of the evacuation of the contrast medium. A laparoscopy was performed with the clinic for low intestinal obstruction. Revision of the intestine revealed a tumor-like formation measuring 6 4 cm at 60 cm from the ileocecal angle. A minilaporotomy was performed, a 10 cm section of the ileum was resected, bearing a tumor-like formation with an end-to-end anastomosis. The postoperative period is favorable. The girl was discharged from the hospital on the eighth postoperative day. On histological examination, pancreatic tissue was found in the wall of the small intestine, with duct ectasia. At the follow-up examination after one year. the patient had no complaints with normal growth and development. This clinical observation demonstrates the nonspecificity of the clinical picture and the difficulty of diagnosing pancreatic ectopia, and the advantages of minimally invasive interventions that allow diagnosing a rare pathology and its timely adequate correction.
Sixth All-Russian congress with international participation “Medical care in trauma. New in organization and technology. The role of the national public professional organization of traumatologists in the healthcare system of the Russian Federation”
Authors: Petlakh Vladimir I.
Published: March 2021

Information from the upcoming congress of orthopedic traumatologists.
Heuristics, language and medical errors
Authors: Graber Mark A.
Published: March 2021

The use of heuristics, cognitive rules of thumb or shortcuts, are a common part of medical decision making. While using heuristics lessens the cognitive burden of decision making and often comes up with the correct answer, reliance on heuristics can also lead to medical errors. In this introduction we will define heuristics and discuss some of the more common heuristics/biases that may lead to biased decision making and patient harm. We will also look at the use of language in medicine and how that can lead us to make diagnostic errors.
Characterizing Stress Orientations in Southern Kansas
Authors: Skoumal Robert J. , Cochran Elizabeth S. , Kroll Kayla A. , Rubinstein Justin L. , McPhillips Devin
Published: March 2021

Induced seismicity predominantly occurs along faults that are optimally oriented to the local principal compressive stress direction, and the characterization of these stress orientations is an important component of understanding seismic hazards. The seismicity rate in southern Kansas rapidly increased in 2013 primarily due to the disposal of large volumes of wastewater into the Arbuckle Group. Previously, local stress orientations in this area were poorly constrained, which limited our understanding of the complex faulting and diverse earthquake mechanisms in this region. We use shear-wave splitting and focal mechanism inversion techniques to create multiple, independent estimates of maximum horizontal stress directions (SHmax) and their spatial variation across the study area. We then create an integrated model of stress orientations for southern Kansas and northern Oklahoma using our local results in conjunction with previous, regional stress orientation estimates. We find that SHmax in both southern Kansas and central Oklahoma exhibits an east-northeast (∼N78° E) orientation, and these regions bound a northeast (∼N59° E) rotation within a ∼20  km area in northern Oklahoma near the Nemaha ridge.
La seguridad como componente de la calidad de un destino turístico: aproximación al caso de Galicia
Authors: Álvarez de la Torre Jaime , Rodríguez-Toubes Muñíz Diego
Published: March 2021

La seguridad está cobrando importancia en la elección de un destino y ha pasado a ser una de las variables decisivas. Hoy en día se ha convertido en un indicador más de competitividad. Esta nueva dimensión turística guarda mucha similitud con la cultura de la calidad: ambas disciplinas buscan como objetivo la ausencia de defectos. A pesar de que Galicia se considera como un destino seguro, se ha visto afectada también por sucesos negativos; por este motivo, Galicia debería explotar su imagen de destino seguro y de calidad. Este estudio se ha llevado a cabo mediante entrevistas en profundidad con diversos expertos en distintos sectores.
Sustainable development and rural tourism in Lithuania
Authors: Bučienė Romantė , Merkienė Jūrate Merkienė
Published: March 2021

The article deals with the importance of sustainable development and rural tourism in Lithuania. The issues concerning the establishing and maintaining of a homestead in a rural environment are reviewed. Communication skills, business planning and language skills are of utmost importance in the flourishing of rural tourism in Lithuania. The future world of business has to change if we are to overcome the crises in society and in the personality. The social responsibility of educational institutions is high on the agenda. Business companies have to be socially responsible and eco-friendly particularly what concerns rural tourism.
La subversión del edén mazatleco. Empresarialismo turístico especulativo en la Isla de la Piedra
Authors: Ibarra Guillermo Eduardo , Moreno Adriana
Published: March 2021

A partir de la evaluación del impacto en el desarrollo urbano portuario que tendrá Mazatlán, ubicado en el litoral del Pacífico, a consecuencia de la apertura de la carretera transoceánica que lo conectará con Matamoros, en el Océano Atlántico, formando el Corredor Económico del Norte de México, se muestra la inviabilidad y el carácter utópico y especulativo del proyecto turístico Amaitlán. Garden City, Mazatlán, localizado en la Isla de la Piedra, que se promociona por una inmobiliaria privada como ciudad verde, sustentable, capaz de generar una motricidad económica regional que duplique el mercado de trabajo local en un plazo de cincuenta años. Las tierras comunales de propiedad ejidal de los pobladores de la Isla han entrado en un juego especulativo que a mediano plazo afectará su patrimonio y su hábitat, cayendo en una lógica de acumulación por desposesión. Bajo estas circunstancias se concluye que Mazatlán no cuenta con capacidades para la innovación socio institucional del territorio turístico, corroborándose en Amaitlán.
Ciudad saludable, ciudad turística. Espacialización de imaginarios y prácticas urbanas (Rosario, Argentina)
Authors: Vera Paula
Published: March 2021

El creciente proceso de turistificación de la ciudad y la ponderación de la experiencia urbana encuentra en el imaginario de lo saludable un recurso de competitividad que, por un lado repercute en la construcción de ciertos espacios urbanos y, por otro, induce a la promoción de ciertas prácticas y hábitos. El objetivo principal de este artículo es analizar las condiciones de posibilidad que operan en la conformación del imaginario urbano saludable en Rosario (Argentina), cómo incide en su proceso de turistificación y, por último, cómo interviene en la configuración del espacio público. Se emplea una estrategia metodológica cualitativa que combina el relevamiento documental y hemerográfico y el análisis de contenido de discursividades oficiales en torno a la planificación urbana y turística en combinación con recorridos etnográficos por los espacios urbanos para reconstruir algunos rasgos que nos permitan comprender las estrategias de composición urbana y turística. Se pudo comprobar que la imaginación espacial de lo saludable anclada en el espacio público recupera algo de la matriz de sentidos del higienismo decimonónico y lo actualiza a  través de un disciplinamiento específico de la experiencia corporal en la ciudad contemporánea donde se intersectan lo turístico, la salud y la belleza. Esta imaginería se materializa en discursos y planificaciones, en la reconfiguración de las prácticas y espacios urbanos y, fundamentalmente, en la emergencia de una nueva subjetividad: el paciente/turista