bluuebunny/crossref_metadata_2025 huggingface dataset:
Rezension von: Franz, Günther, Der Dreißigjährige Krieg und das deutsche Volk
Authors: Taddey Gerhard , Franz Günther
Published: February 2024

Günther Franz: Der Dreißigjährige Krieg und das deutsche Volk (= Quellen und Forschungen zur Agrargeschichte, 7). 4. neu bearb. u. verm. Aufl. Stuttgart, New York: Fischer 1979. 140 S., 28 Abb.
Rezension von: Speer, Albert, Der Sklavenstaat
Authors: Koziol Michael Sylvester , Speer Albert
Published: February 2024

Albert Speer: Der Sklavenstaat. Meine Auseinandersetzungen mit der SS. Stuttgart: Deutsche Verlags-Anstalt 1981. 510 S.
Rezension von: Fuchs, Werner u.a. (Hrsg.), Lexikon der Soziologie
Authors: Ulshöfer Kuno , Fuchs-Heinritz Werner
Published: February 2024

Lexikon der Soziologie. Hrsg. von Werner Fuchs, Rolf Klima [u.a.]. 2. verb. u. erw. Aufl. Opladen: Westdeutscher Verlag 1978. 890 S.
Rezension von: Gawlik, Alfred (Bearb.), Die Urkunden Heinrichs IV. Dritter Teil
Authors: Taddey Gerhard , Gawlik Alfred
Published: February 2024

Die Urkunden Heinrichs IV. Dritter Teil. Bearb. von Alfred Gawlik (= Monumenta Germaniae Historica. Die Urkunden der deutschen Könige und Kaiser, 6). Hannover: Hahnsche Buchhandlung 1978. CII, 687-1102 S.
Rezension von: Klein, Michael, Die Handschriften der Sammlung J 1 im Hauptstaatsarchiv Stuttgart
Authors: Ulshöfer Kuno , Klein Michael
Published: February 2024

Die Handschriften der Sammlung J 1 im Hauptstaatsarchiv Stuttgart. Bearb. von Michael Klein (= Die Handschriften der Staatsarchive in Baden-Württemberg, 1). Wiesbaden: Harrassowitz 1980. 560 S.
Rezension von: Bund für Deutsche Schrift (Hrsg.), Die deutsche Schrift Heft 65 (1981)
Authors: Ulshöfer Kuno , Bund für Deutsche Schrift
Published: February 2024

Die deutsche Schrift. Blätter zur Förderung des Schriftwesens. Heft 65 (1981), 40 S.; Heft 66 (1982), 48 S.
Rezension von: Rödel, Ute, Königliche Gerichtsbarkeit und Streitfälle der Fürsten und Grafen im Südwesten des Reiches 1250-1313
Authors: Weber Raimund J. , Rödel Ute
Published: February 2024

Ute Rödel: Königliche Gerichtsbarkeit und Streitfälle der Fürsten und Grafen im Südwesten des Reiches 1250-1313 (= Quellen und Forschungen zur höchsten Gerichtsbarkeit im Alten Reich, hrsg. von Bernhard Diestelkamp, Ulrich Eisenhardt [u.a.], 5). Köln, Wien: Böhlau 1979 (Diss. phil. Mainz 1978). 215 S.
Rezension von: Deetjen, Werner-Ulich, Studien zur Württembergischen Kirchenordnung Herzog Ulrichs 1534-1550
Authors: Zieger Andreas , Deetjen Werner-Ulrich
Published: February 2024

Werner-Ulrich Deetjen: Studien zur Württembergischen Kirchenordnung Herzog Ulrichs 1534-1550. Das Herzogtum Württemberg im Zeitalter Herzog Ulrichs (1498-1550), die Neuordnung des Kirchengutes und der Klöster (1534-1547) (= Quellen und Forschungen zur Württembergischen Kirchengeschichte, 7). Stuttgart: Calwer Verl. 1981. XLIII, 561 S.
Rezension von: Beyreuther, Erich, Geschichte des Pietismus
Authors: Wissner Martin , Beyreuther Erich
Published: February 2024

Erich Beyreuther: Geschichte des Pietismus. Stuttgart: Steinkopf 1978. 448 S.
Rezension von: Lahnstein, Peter, Die unvollendete Revolution 1848-1849
Authors: Göpfert Eberhard , Lahnstein Peter
Published: February 2024

Peter Lahnstein: Die unvollendete Revolution 1848-1849. Badener und Württemberger in der Paulskirche. Stuttgart: Kohlhammer 1982. 259 S.
Rezension von: Linck, Otto, 50 Jahre Triasforschung im Heilbronner Raum
Authors: Hagdorn Hans , Linck Otto
Published: February 2024

Otto Linck: 50 Jahre Triasforschung im Heilbronner Raum (= Heilbronner Museumshefte, 8). Heilbronn: Städt. Museen 1981. 86 S., 60 Abb.
Rezension von: Dettelbacher, Werner, Typisch fränkisch
Authors: Wunder Gerd , Dettelbacher Werner
Published: February 2024

Werner Dettelbacher: Typisch fränkisch. Blicke in Geschichtliches, Zeitgenössisches, in Charaktere, Küchen, Keller und Kirchweihen. Frankfurt a. M.: Weidlich 1982. 183 S.
Rezension von: Sydow, Jürgen (Hrsg.), Städtische Versorgung und Entsorgungim Wandel der Geschichte
Authors: Windmüller Otto , Sydow Jürgen
Published: February 2024

Städtische Versorgung und Entsorgungim Wandel der Geschichte. Hrsg. von Jürgen Sydow (= Stadt in der Geschichte, 8). Sigmaringen: Thorbecke 1981. 214 S.
Rezension von: Piechocki, Werner, Die Halloren
Authors: Hagdorn Karin , Piechocki Werner
Published: February 2024

WernerPiechocki: Die Halloren. Geschichte und Tradition der »Salzwirkerbrüderschaft im Thale zu Halle«. Mit Fotos von Walter Danz. Leipzig: Koehler & Amelang 1981. 192 S., 98 Abb.
Rezension von: Seiler, Alois (Bearb.), Ellwangen von der Klostersiedlung zur modernen Flächenstadt
Authors: Gerhardt Thomas , Seiler Alois
Published: February 2024

Ellwangen, von der Klostersiedlung zur modernen Flächenstadt. Dokumente und Bilder. Katalog bearb. von Alois Seiler zur Ausstellung Stadt Ellwangen und Staatsarchiv Ludwigsburg. Ellwangen: Schwaben Verl. 1979. 156 S., Katalogteil, Abb.
Rezension von: Krabbe, Helmuth u.a. (Hrsg.), Akten zur Esslinger Reformationsgeschichte
Authors: Wissner Martin , Krabbe Helmuth
Published: February 2024

Helmuth Krabbe/Hans-Christoph Rublack: Akten zur Esslinger Reformationsgeschichte (= Esslinger Studien. Schriftenreihe, 5. Hrsg. vom Stadtarchiv Esslingen am Neckar). Sigmaringen: Thorbecke 1981. 336 S.
Rezension von: Frank, Karl Suso, Das Klarissenkloster Söflingen
Authors: Zieger Andreas , Frank Karl Suso
Published: February 2024

Karl Suso Frank: Das Klarissenkloster Söflingen. Ein Beitrag zur franziskanischen Ordensgeschichte Süddeutschlands und zur Ulmer Kirchengeschichte (= Forschungen zur Geschichte der Stadt Ulm, 20). Ulm 1980. 232 S.
Rezension von: Buck, Michael Richard, Medicinischer Volksglauben u. Volksaberglauben aus Schwaben
Authors: Ulshöfer Kuno , Buck Michael Richard
Published: February 2024

M(ichael) R(ichard)Buck: Medicinischer Volksglauben u. Volksaberglauben aus Schwaben. Eine kulturgeschichtliche Skizze. Reprint. 3. Aufl. Riedlingen: Ulrich 1980. 72 S.
Rezension von: Vita Caroli Quarti. Die Autobiographie Karls IV.
Authors: Taddey Gerhard , Karl IV. Heiliges Römisches Reich
Published: February 2024

Vita Caroli Quarti. Die Autobiographie Karls IV. Einführung, Übersetzung und Kommentar von Eugen Hillenbrand. Stuttgart: Fleischhauer und Spohn 1979. 248 S., 8 Bildtaf., 3 Stammtaf.
Rezension von: Schueler, Hermann, Auf der Flucht erschossen
Authors: Ulshöfer Kuno , Schueler Hermann Kurt
Published: February 2024

Hermann Schueler: Auf der Flucht erschossen. Felix Fechenbach 1894-1933. Köln: Kiepenheuer und Witsch 1981. 303 S.
Rezension von: Strauss, Walter (Hrsg.), Lebenszeichen
Authors: Taddey Gerhard , Strauss Walter
Published: February 2024

Lebenszeichen. Juden aus Württemberg nach 1933. Hrsg. von Walter Strauss. Gerlingen: Bleicher 1982. 367 S.
Estimating individual responses when tomorrow matters
Authors: Bonhomme Stéphane , Denis Angela
Published: February 2024

We propose a regression-based approach to estimate how individuals’ expectations influence their responses to a counterfactual change. We provide conditions under which average partial effects based on regression estimates recover structural effects. We propose a practical three-step estimation method that relies on subjective beliefs data. We illustrate our approach in a model of consumption and saving, focusing on the impact of an income tax that not only changes current income but also affects beliefs about future income. Applying our approach to Italian survey data, we find that individuals’ beliefs matter for evaluating the impact of tax policies on consumption decisions.
Análisis de la dinámica reciente de la inflación en españa. Un enfoque basado en el modelo de Blanchard y Bernanke (2023).
Authors: Ghomi Morteza , Hurtado Samuel , Montero José Manuel
Published: February 2024

El reciente episodio inflacionista responde a la conjunción de varias perturbaciones cercanas en el tiempo. En este documento utilizamos el modelo de Blanchard y Bernanke (2023) como marco analítico para evaluar el peso relativo de los distintos factores explicativos en diferentes etapas de este episodio. De acuerdo con los resultados obtenidos, se pueden extraer dos conclusiones principales. En primer lugar, las perturbaciones por el lado de la oferta (energía, alimentos, cuellos de botella) han tenido un papel fundamental en la evolución reciente de la inflación en la economía española. En segundo lugar, una vez absorbidas las mencionadas perturbaciones de oferta, el tensionamiento del mercado laboral estaría ganando un mayor peso relativo como factor determinante de la inflación, con un impacto que podría exhibir un mayor grado de persistencia en el futuro.
Climate change as a factor of regional changes in energy consumption (natural gas, electricity)
Authors: Лазовский А.И.
Published: February 2024

На основе анализа климатических показателей и данных тепло- и электроэнергетики предприятий Лабинского района Краснодарского края выявлены тренды динамик полезного отпуска природного газа и электроэнергии потребителям. Определены взаимосвязь и перспективы расхода энергоресурсов с учетом общерегио-нальных изменений климата, а также в разрезе и по сезонам местных климатических особенностей рассматриваемого района. Многолетние данные были сформированы по приземной температуре воздуха в ФГБОУ «Краснодарская ВС» и на Метеостанции Ла-бинского филиала КЦГМС ФГБОУ «Северо - Кавказское УГМС»; по отпуску, расходу га-за и электроэнергии потребителям частного сектора и юридическим лицам в МУП г. Лабинска «Тепловые сети», в филиале г. Лабинска АО «Газпром газораспределение Краснодар», в Лабинском филиале АО «НЭСК», в Лабинском филиале ПАО «Россети Ку-бань». Установлено, что изменение климата ведет к неоднозначной динамике расхода (потребления) энергоресурсов, а именно с повышением приземной температуры воздуха существует устойчивая тенденция экономии ресурсов в теплоэнергетики района и, в тоже время она сомнительна для электроэнергетики.

The work is devoted to the analysis of climatic data and data of heat and elec-tric power of enterprises on the example of the Labinsky district of the Krasnodar Territory. The article identifies trends in the dynamics of the useful supply of natural gas and electricity to con-sumers of the Labinsk region, determines the relationship and prospects of energy consumption, taking into account, both in general, with regional climate changes, and in the context of sea-sons, taking into account local climatic features of the area under consideration. Long-term da-ta, based on the results of the analysis of which conclusions were drawn, were directly collected: on the surface air temperature in the Krasnodar VS FSUE (hereinafter KVS) and at the Labinsk Weather Station of the North Caucasian UGMS branch of the North Caucasian UGMS FSUE (hereinafter MS Labinsk); on vacation, gas and electricity consumption, private sector consum-ers and to legal entities, in the Municipal Unitary Enterprise of Labinsk “Thermal Networks”, in the Labinsk branch of JSC Gazprom Gas Distribution Krasnodar, in the Labinsk branch of JSC NESK, in the Labinsk branch of PJSC Rosseti Kuban. As a result of the analysis, it was found that climate change leads to ambiguous changes in the dynamics of energy consumption (con-sumption). With an increase in surface air temperature, there is a steady tendency to save re-sources in the district’s thermal power industry, at the same time it is questionable for the elec-tric power industry.
Death as a sign system - seeking eternity by Boris Pasternak in “Doctor Zhivago”
Authors: Му Д.
Published: February 2024

Статья посвящена анализу знаковой системы смерти в романе «Доктор Живаго». Бинарная система между «жизнью» и «смертью» - распространенный жанр в литературе, а Б. Пастернак не намерен акцентировать внимание на конфликте между ними, он не привязан к скоротечности жизни. Данное произведение – запись размышлений автора о жизни и его искания бессмертия. Исследование в большей степени основано на теории культурной семиотики Ю. Лотмана, на базе теории семиосферы. Анализируется семиосфера «смерть», представленная такими знаками, как могила, похороны, отношение людей к смерти, болезнь, перерывы, война. То, что профессия главного героя Ю. Живаго - врача – стоит на границе между семиосферами смерти и жизни, является метафорой именно данной темы. Установлено, что автор находит два выхода из смерти – материальный и духовный: материальный – с опорой на продолжение жизни в следующем поколении для достижения бессмертия человечества; а духовный – с помощью искусства для приведения жизни к бессмертию.

The article is devoted to the analysis of the sign system of death in the novel “Doctor Zhivago”. The binary system between “life” and “death” is a common genre in literature, but B. Pasternak does not intend to emphasize the conflict between them, he is not attached to the transience of life. This work is a record of the author's reflections on life and his seeking for eternity. The article is based on Yu. Lotman's theory of cultural semiotics, using the semiosphere theory to analyze and study this novel. The sign system of “death” is represented by such symbols as grave, funeral, people's attitude to death, disease, coma, war and so on. The fact that the profession of Yu. Zhivago as a doctor lies on the border between the semiospheres of death and life, is a metaphor for just such a theme of the novel. The author finds two ways of escape from death - material and spiritual: material - with reliance on the continuation of life in the next generation to achieve the immortality of mankind; and spiritual - with the help of art to bring life to eternity. The novelty of this article lies in the use of semiosphere theory in analyzing the sign system of death and the theme of seeking eternity.
Metamodernist text of the story by A. and I. Shaov “Patient No. 132, or Live here and now”
Authors: Напцок Б.Р. , Напцок М.Р.
Published: February 2024

Статья посвящена исследованию метамодернистского текста. На материале повести Асфара и Ибрагима Шаовых авторы выявляют и анализируют принципы организации повествования, формирующие метамодернистский дискурс произведения: модель мира, художественную концепцию личности, авторские стратегии.

This paper delves into the realm of metamodernism, focusing on the analysis of a metamodernist text. By employing the captivating story by Asfar and Ibrahim Shaov, this study uncovers and analyzes the fundamental principles of narrative construction that give rise to the metamodernist discourse within the work. These principles encompass the model of the world, the artistic conceptualization of personality, and the author's strategic choices.
Genre of the novel in Adyghe literature of the late 20th - early 21st centuries
Authors: Ахметова Д.А.
Published: February 2024

Статья посвящена адыгейской романистике конца ХХ – начала ХХI веков, ее важнейшим проблемам, основным направлениям, наиболее интересным явлениям. Исследуется важный этап в истории национального романа, научного обобщения опыта адыгейских писателей в этой области литературного творчества. Раскрываются характерные черты и тенденции развития современного адыгейского романа, констатируется влияние времени и социальных, нравственных и эстетических проблем. Для романа 90-х годов ХХ в. и начала ХХI в. характерны демократизм и гуманизм художественного творчества, ускорение в нем трансформационных процессов, отражающих перемену идеологических ориентиров и переоценку устоявшихся художественных ценностей. Отмечается смелое новаторство авторов, многообразие в романе стилевых решений, сопрягающих элементы разных художественных систем (реализм, модернизм, постмодернизм) и создающих новые модификации эпических жанров (мифоэпический, полифункциональный, философский роман в русле магического реализма).

The article aims to study Adyghe novelistic literature of the late 20th – early 21st centuries, its important issues, main directions, and most interesting features. It examines an important stage in the history of the national novel, the scientific synthesis of the experience of Adyghe writers in this field of literature. The characteristic features and trends of the contemporary Adyghe novel are revealed, as well as the influence of time and social, moral, and aesthetic problems. The novels of the 1990s and the beginning of the 21st century are characterized by the democratization and humanism of artistic creativity, the acceleration of transformative processes reflecting the change in ideological orientations and reassessment of established artistic values. The authors' bold innovation, the diversity of stylistic solutions in the novel combining elements of different artistic systems (realism, modernism, postmodernism), and the creation of new modifications of epic genres (mytho-epic, polyfunctional, philosophical novel in the realm of magical realism) are noted.
Features of updating the components-zoonyms "camel" and "lion" in the phraseology of the Arabic and Russian languages
Authors: Альмухаммадага Х.А.Ф.
Published: February 2024

В статье исследуется проблема анималистических фразеологизмов на материале арабского и русского языков. Фразеологизмы с компонентами-зоонимами составляют значительную часть фразеологической картины мира любого национального сообщества со специфической языковой и концептуальной картиной мира. Устанавливается количество фразеологизмов общих значений в этих языках. Частотность зоонимов верблюд и лев в арабском языке обусловливает не только дифференцированность значений компонентов в составе фразеологизмов арабского языка, но также их амбивалентную актуализацию. Исходя из большого корпуса фразеологизмов с компонентами-зоонимами в арабском и русском языках, сопоставительное исследование в данном ракурсе имеет интересную перспективу в изучении проблем межкультурной коммуникации и перевода.

The article examines the problem of animalistic phraseological units based on the material of Arabic and Russian languages. Phraseological units with components-zoonyms make up a significant part of the phraseological picture of the world of any national community with a specific linguistic and conceptual picture of the world. The relevance of the work is determined by the need to study the specifics of the implementation of individual animalisms ("camel", "lion") in Arabic and Russian. The study uses a comparative method that helps to identify common and special characteristics of the studied zoonyms as part of phraseological units. As a result of the comparison of phraseological units, a limited number of common meanings in Arabic and Russian have been established. The frequency of the zoonyms "camel" and "lion" in the Arabic language determines not only the differentiation of the meanings of the components in the phraseological units of the Arabic language, but also their ambivalence. Based on the large corpus of phraseological units with components-zoonyms in Arabic and Russian, comparative research in this perspective has an interesting perspective in the direction of studying the problems of intercultural communication and translation.
Evaluation of the diagnostic performance of estimated fecal calprotectin and serum intelectin-1 and C-reactive protein solo or in combination for differentiation between patients with query ulcerative colitis, Crohn’s disease and irritable bowel syndrome
Authors: Fellak Naima
Published: February 2024

Background: Gut-brain contact has been linked recently to functional gastrointestinal problems. This interaction begins with immune cells invading the mucosa, which then causes intestinal cells to release nociceptive mediators either directly or indirectly. These mediators can cause visceral hypersensitivity by activating sensitized neurons. Reduced serum levels of intelectin-1 may distinguish among studied cases with UC & healthy controls as well as among IBS studied cases & studied cases with UC. This is as UC studied case samples had significantly lower levels of ITLN1 than do control & IBS studied case samples, & IBS studied case samples & healthy controls did not differ significantly. Aim: in this review; Our objective was to assess the diagnostic efficacy of serum intelectin-1, C-reactive protein, & estimated faecal calprotectin alone or in combination for distinguishing individuals with ulcerative colitis from those with irritable bowel syndrome, Summary: High FCP & low serum ITLN1 together can be able to distinguish UC from IBS, predict colonoscopic & microscopic results of UC, & avoid the need for colonoscopy & biopsy, particularly in IBS studied cases. Raised FCP & lowered serum ITLN1 may distinguish UC from IBS by precisely predicting the microscopic & colonoscopic diagnostic results of UC.
ANALISIS PENGARUH BEAUTY VLOGGER DAN CITRA MEREK TERHADAP KEPUTUSAN PEMBELIAN PRODUK MS GLOW DI KABUPATEN SEMARANG
Authors: Nurfika  , Ahmad Dwi Nurdiyanto  , Teti Safari
Published: February 2024

Penelitian ini dilatar belakangi oleh perkembangan beauty vlogger sebagai keunikan yang dapat mempengaruhi pelanggan dalam berpikir dan dalam keputusan pembelian. Hal ini didasarkan pada perusahaan sebagai peluang untuk mendapatkan minat dari konsumen dengan memanfaatkan kekuatan atau daya tarik figur endorser. Keunikan ini digunakan sebagai bantuan oleh pembuat di setiap gerakan periklanan untuk menyampaikan citra dan struktur karakter mereka dan mencirikan merek gambar barang atau produk yang dipromosikan. Maka dari itu dalam penelitian ini bertujuan untuk mengetahui beauty vlogger dan citra merek terhadap keputusan pembelian. Metode penelitian yang digunakan adalah penelitian pendekatan kuantitatif, dengan model pengumpulan data kuesioner melalui google form. Dengan menggunakan 100 sampel pembeli produk MS Glow yang ada di daerah Kabupaten Semarang. Hasil penelitian ini menunjukan bahwa beauty vlogger (X1) berpengaruh dan signifikan pada keputusan pembelian.
PENGARUH LINGKUNGAN KERJA, KOMPENSASI DAN KEPEMIMPINAN TERHADAP KINERJA KARYAWAN DI PT. SEMARANG AUTOCOMP MANUFACTURING INDONESIA (SAMI) KOTA SEMARANG BARAT JAWA TENGAH
Authors: Murniati  , Jasman Indradno  , Teti Safari
Published: February 2024

Tujuan dari penelitian ini : 1) Mengetahui dan menganalisis pengaruh antara Lingkungan Kerja terhadap Kinerja Karyawan, 2) Mengetahui dan menganalisis pengaruh antara Kompensasi terhadap Kinerja Karyawan, 3) Mengetahui dan menganalisis pengaruh antara Kepemimpinan terhadap Kinerja Karyawan, 4) Mengetahui dan menganalisis pengaruh secara bersama-sama antara Lingkungan Kerja, Kompensasi dan Kepemimpinan terhadap Kinerja Karyawan. Populasi dalam penelitian ini adalah karyawan PT. Semarang Autocomp Manufacturing Indonesia tahun 2023. Dalam pemilihan sampel ini menggunakan purposive sampling dan accidental sampling dengan jumlah 100 responden. Jenis data yang digunakan adalah data primer. Analisis data menggunakan analisis regresi linier berganda. Hasil penelitian dapat disimpulkan bahwa : 1) Lingkungan Kerja berpengaruh signifikan terhadap Kinerja Karyawan, 2) Kompensasi berpengaruh signifikan terhadap Kinerja Karyawan, 3) Kepemimpinan berpengaruh signifikan terhadap Kinerja Karyawan, 4) Lingkungan Kerja, Kompensasi dan Kepemimpinan berpengaruh signifikan secara bersama-sama terhadap Kinerja Karyawan.
PENGARUH DISKON, PROMOSI, DAN KEPERCAYAAN KONSUMEN TERHADAP KEPUTUSAN PEMBELIAN ONLINE PADA TOKO EFABRIC DI KOTA SEMARANG
Authors: Anis Fatmawati  , Heru Yulianto  , Ahmad Dwi Nurdiyanto
Published: February 2024

Tujuan dari penelitian ini adalah untuk mengetajui dan menganalisis pengaruh diskon, promosi dan kepercayaan konsumen terhadap keputusan pembelian online pada toko Efabric di kota semarang secara parsial. Populasi dalam penelitian ini adalah konsumen yang pernah melakukan pembelian online di Toko Efabric di Kota Semarang, sebanyak 100 responden. Jenis penelitian yang digunakan adalah kuantitatif. Pengambilan sampel menggunakan teknik simple random sampling, teknik analisis yang digunakan regresi linier berganda metode skala likert. Hasil penelitian ini menunjukkan bahwa: (1) variabel Diskon berpengaruh positif dan signifikan terhadap Keputusan Pembelian online pada toko Efabric Semarang; (2) variabel Promosi berpengaruh positif dan signifikan terhadap Keputusan Pembelian online pada toko Efabric di Kota Semarang; dan (3) variabel Kepercayaan Konsumen berpengaruh positif dan signifikan terhadap Keputusan Pembelian online pada toko Efabric di Kota Semarang.
Real-world data: A relevant component in the framework of scientific evidence
Authors: Canonica Giorgio W. , Del Moro Lorenzo , Costanzo Giovanni , Nappi Emanuele , Paoletti Giovanni
Published: February 2024

Explanatory randomized controlled clinical trials test hypotheses to see if the intervention causes an outcome of interest in optimal circumstances, that is, established by selecting patients based on inclusion and exclusion criteria and controlled environments. They assess the “efficacy” of an intervention. On the contrary, it is crucial for society to address issues related to real-world clinical practices. This need can be fulfilled by real-world studies. We discuss the challenges in obtaining real-world evidence in asthma, debating the importance of including patients who are typically excluded from randomized controlled clinical trials to ensure the generalizability of the results. We conclude by discussing the integration of real-world evidence in guidelines and the need for standard rules to use real-world evidence in guidelines.
Management of hereditary angioedema in resource-constrained settings: A consensus statement from Indian subcontinent
Authors: Jindal Ankur Kumar , Sil Archan , Aggarwal Ridhima , Vinay Keshavamurthy , Bishnoi Anuradha , Suri Deepti , Rawat Amit , Kumaran Muthu Sendhil , Saikia Biman , Sarkar Rashmi , Gupta Lalit , Kumar D Dinesh , Jindal Rashmi , Sukumaran T U , Ouseph Jose , Longhurst Hilary , Pawankar Ruby , Singh Surjit , Dogra Sunil
Published: February 2024

Hereditary angioedema (HAE) is an uncommon disorder characterized clinically by recurrent episodes of nonitchy subcutaneous and/or submucosal swellings. The estimated prevalence of HAE is ~ 1: 10,000 to 1: 50,000. There are no prevalence data from India, however, estimates suggest that there are 27,000 to 135,000 patients with HAE in India at present. The majority of these, however, remain undiagnosed.

Replacement of plasma-derived or recombinant C1-esterase inhibitor (C1-INH) protein, administered intravenously, is the treatment of choice during the management of acute episodes of angioedema (i.e., “on-demand treatment”) and is also useful for short-term prophylaxis (STP) and long-term prophylaxis (LTP). This has been found to be effective and safe even in young children and during pregnancy.

Until recently, none of the first-line treatment options were available for “on-demand treatment,” STP or LTP in India. As a result, physicians had to use fresh frozen plasma for both “on-demand treatment” and STP. For LTP, attenuated androgens (danazol or stanozolol) and/or tranexamic acid were commonly used. These drugs have been reported to be useful for LTP but are associated with a significant risk of adverse effects.

Intravenous pd-C1-INH, the first-line treatment option, is now available in India. However, because there is no universal health insurance, access to pd-C1-INH is a significant challenge.

HAE Society of India has developed these consensus guidelines for India and other resource-constrained settings where plasma-derived C1-INH therapy is the only available first-line treatment option for the management of HAE and diagnostic facilities are limited. These guidelines have been developed because it may not be possible for all patients to access the recommended therapy and at the recommended doses as suggested by the international guidelines. Moreover, it may not be feasible to follow the evaluation algorithm suggested by the international guidelines.
Optimal period for achieving sustained unresponsiveness in peanut oral immunotherapy
Authors: Yamashita Kosei , Nakamura Toshinori , Imai Takanori , Honda Aiko , Okada Yuki , Maeda Mayu , Kamiya Taro
Published: February 2024

Background:

Oral immunotherapy (OIT) can help children with persistent food allergies achieve sustained unresponsiveness (SU). However, the optimal therapeutic period for obtaining SU remains unclear.

Objective:

We aimed to retrospectively investigate the association between the OIT treatment period and achievement of SU.

Methods:

We enrolled patients who received OIT for peanut allergy between January 1, 2018 and December 31, 2022. OIT comprised the build-up phase, maintenance phase, complete avoidance, and an oral food challenge (OFC) for confirming SU. The peanut dose in the OFC was gradually increased to 3,000 mg (peanut protein: 795 mg), which was subsequently maintained for ≥5 months. SU was defined as a negative response to 795 mg of peanut protein after ≥2 weeks of complete avoidance. We evaluated the therapeutic OIT period for achieving SU using Kaplan–Meier analysis.

Results:

Forty-eight patients underwent peanut OIT. The starting age at OIT initiation was 8 (interquartile range [IQR], 7–10) years. Forty-one (85%) patients had a history of anaphylaxis. The median specific immunoglobulin E concentration to peanut and Ara h 2 at OIT initiation was 85.3 (IQR, 33.7–100) and 57.6 (IQR, 21.9–100) UA/mL, respectively. The median observational period was 2.1 (IQR, 1.6–3.0) person-years (PY). Thirty-four (71%) patients achieved SU, with the rate of SU achievement gradually increasing with the therapeutic period. The median period until SU achievement was 2.1 (95% confidence interval, 1.6–2.5) PY. The rate of SU achievement slowed down after 2.7 PY.

Conclusion:

OIT for at least 2.7 PY can increase the rate of SU achievement. The protocol No. 3107.
Evaluating immune responses to pneumococcal vaccines
Authors: Thong Bernard Yu-Hor , Pawankar Ruby , Park Hae-Sim , Abdul Latiff Amir Hamzah
Published: February 2024

Streptococcus pneumoniae (pneumococcus) is a significant cause of bacterial infections ranging from mild infections affecting the respiratory tract such as otitis media and sinusitis to severe diseases including bacteremia, pneumonia, and invasive pneumococcal disease (IPD) (eg, meningitis, septic arthritis, and endocarditis). Pneumococcal vaccines were first developed in the 1970s as capsular pneumococcal polysaccharide vaccines, which were T-cell independent and hence lacked immunologic memory. Subsequently in the year 2000, pneumococcal conjugate vaccines (PCV) conjugated to a protein to increase immunogenicity were developed and made commercially available. The increasing number of pneumococcal serotypes identified and the expanding pipeline of PCV vaccines with improved immunogenicity have significantly reduced the morbidity and mortality associated with IPD in high-risk patients. Pneumococcal vaccines also play an important role in the diagnosis and immunophenotyping of children and adults with inborn errors of immunity (IEI) given the increasing diversity/heterogeneity of IEI presenting with primary and/or specific antibody deficiency. Other than the quantitation of serotype levels in routine clinical care, other measurements of immune response including the functional activity of antibodies, antibody avidity, cell-mediated immunity, and immunological memory remain limited to clinical trials during vaccine development.
APAAACI clinical pathway on direct provocation testing for penicillin allergy delabeling
Authors: Li Philip Hei , Thong Bernard Yu-Hor , Pawankar Ruby , Jeewandara Chandima , Lobo Rommel Crisenio M. , Kang Hye-Ryun , Mahesh Padukudru Anand , Meng Juan , Munkhbayarlakh Sonomjamts , Pham Duy Le , Rerkpattanapipat Ticha , Tang Min-Moon , Yamaguchi Masao , Abdul Latiff Amir Hamzah , Rengganis Iris , Wang Jiu-Yao , Zhang Luo , Lucas Michaela
Published: February 2024

Background:

Allergy to penicillin is commonly reported in many countries and is an overwhelming global public health concern. Penicillin allergy labels can lead to the use of less effective antibiotics and can be associated with antimicrobial resistance. Appropriate assessment of suspected penicillin allergy (often including skin testing, followed by drug provocation testing [DPT] performed by allergists) can prevent the unnecessary restriction of penicillin or delabelling. Many countries in the Asia Pacific (AP) have very limited access to allergy services, and there are significant disparities in the methods of evaluating penicillin allergy. Therefore, a clinical pathway for the management of penicillin allergy is essential.

Objectives:

To develop a risk-stratified clinical pathway for delabeling penicillin allergy, taking into account the distinct epidemiology, patient/sensitization profiles, and disparities of allergy services or facilities within the AP.

Methods:

A risk-stratified penicillin allergy delabeling clinical pathway was formulated by the Drug Allergy Committee of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology. and members of the Penicillin Allergy Disparities survey in AP each representing one country/region of the AP. The clinical pathway was tested based on a database of anonymized patients who were sequentially referred for and completed penicillin allergy evaluation in Hong Kong.

Results:

The clinical pathway was piloted employing a “hub-and-spoke” approach to foster multidisciplinary collaboration between allergists and nonallergists. A simulation run of the algorithm on a retrospective Hong Kong cohort of 439 patients was performed. Overall, 367 (84%) of patients were suitable for direct DPT and reduced the need for skin testing or specialist’s care for 357 (97%) skin test-negative individuals. Out of the skin test-negative patients, 345 (94%) patients had a negative DPT.

Conclusions:

This risk-stratification strategy for direct oral DPT can reduce the need for unnecessary skin testing in patients with low-risk penicillin allergy histories. The hub and spoke model of care may be considered for further piloting and validation in other AP populations that lack adequately trained allergists.
Examining Air Travellers’ Willingness to Pay for Non-voluntary Environment-related Fees: The Case of SAF Surcharge and Carbon Taxes
Authors:   Department of Tourism and Transport, University of Surrey, GU2 7XH, Guildford, United Kingdom,   These authors contributed equally to this work., Hui Tsz Hin , Itani Nadine ,   Department of Tourism and Transport, University of Surrey, GU2 7XH, Guildford, United Kingdom,   These authors contributed equally to this work., O’Connell John F. ,   Department of Tourism and Transport, University of Surrey, GU2 7XH, Guildford, United Kingdom,   These authors contributed equally to this work.
Published: February 2024

This study aims to investigate air travellers’ Willingness to Pay (WTP) for green premiums, specifically focusing on their contribution to reducing carbon emissions generated by air travel. The research integrates the Theory of Planned Behaviour (TPB) and the Contingent Valuation Method (CVM) to estimate the monetary value that air passengers would be willing to pay for environmental initiatives. The TPB provides a theoretical framework to understand the psychological factors influencing individuals’ intentions and behaviours, while the CVM allows for the estimation of the economic value of environmental goods. Drawing on the TPB, this study examines the influence of attitudes, subjective norms, and perceived behavioural control on air travellers’ WTP for green premiums, while considering the determinants and barriers related to ecological goods, and sustainable consumption. The study investigates the potential economic implications of air travellers’ willingness to pay for green premiums, particularly in the context of sustainable aviation fuel options and carbon-related fees. The findings of the survey of a sample of 248 respondents suggest a general willingness among passengers to pay for environmental premiums, notably carbon taxes, with variations in WTP influenced by demographics, travel preferences, environmental values, and awareness. Notably, younger travellers exhibit the highest WTP which is negatively related to the air ticket price. Higher environmental consciousness correlates with greater WTP. The impact of price perception and perceived efficacy of environmental initiatives were also found significant. Financial constraints and scepticism about the credibility of such premiums, however, limit some passengers’ willingness to contribute.
Pattern Recognition in Medical Images Through Innovative Edge Detection with Robert's Method
Authors: Simangunsong Pandi Barita Nauli , Hasugian Paska Marto
Published: February 2024

This research introduces an innovative approach for pattern recognition in medical images through the application of Robert's edge detection method. Pattern recognition in medical images has great significance in disease diagnosis and patient care management. Edge detection is an important stage in image processing which aims to determine the boundaries of objects in the image. Robert's edge detection method is one of the classic methods that has been used in image processing. However, improving edge detection performance is needed to improve accuracy in pattern recognition in medical images. In this study, we propose a modified variation of Robert's method to increase the accuracy in finding edges in medical images. The proposed innovative approach is tested using a large and diverse medical image dataset. Evaluation is carried out by comparing the edge detection results using the conventional Robert method with the results using the proposed modified method. Quantitative analysis is carried out to measure the performance improvements achieved. Experimental results show that the modified Robert edge detection method produces significant improvements in precision and accuracy in finding edges in medical images. These results indicate that the proposed innovative approach has the potential to improve pattern recognition in medical images and can make valuable contributions in the diagnosis and management of diseases.
Association of Socioeconomic Status With Worse Overall Survival in Patients With Bone and Joint Cancer
Authors: Mani Kyle , Kleinbart Emily , Schlumprecht Anne , Golding Regina , Akioyamen Noel , Song Hyun , De La Garza Ramos Rafael , Eleswarapu Ananth , Yang Rui , Geller David , Hoang Bang , Fourman Mitchell S.
Published: February 2024

Background:

The effect of socioeconomic status (SES) on the outcomes of patients with metastatic cancer to bone has not been adequately studied. We analyzed the association between the Yost Index, a composite geocoded SES score, and overall survival among patients who underwent nonprimary surgical resection for bone metastases.

Methods:

This population-based study used data from the National Cancer Institute's Surveillance, Epidemiology, and End Results database (2010 to 2018). We categorized bone and joint sites using International Classification of Disease-O-3 recodes. The Yost Index was geocoded using a factor analysis and categorized into quintiles using census tract–level American Community Service 5-year estimates and seven measures: median household income, median house value, median rent, percent below 150% of the poverty line, education index, percent working class, and percent unemployed. Multivariate Cox regression models were used to calculate adjusted hazard ratios of overall survival and 95% confidence intervals.

Results:

A total of 138,158 patients were included. Patients with the lowest SES had 34% higher risk of mortality compared with those with the highest SES (adjusted hazard ratio of 1.34, 95% confidence interval: 1.32 to 1.37, P < 0.001). Among patients who underwent nonprimary surgery of the distant bone tumor (n = 11,984), the age-adjusted mortality rate was 31.3% higher in the lowest SES patients compared with the highest SES patients (9.9 versus 6.8 per 100,000, P < 0.001). Patients in the lowest SES group showed more racial heterogeneity (63.0% White, 33.5% Black, 3.1% AAPI) compared with the highest SES group (83.9% White, 4.0% Black, 11.8% AAPI, P < 0.001). Higher SES patients are more likely to be married (77.5% versus 59.0%, P < 0.0001) and to live in metropolitan areas (99.6% versus 73.6%, P < 0.0001) compared with lower SES patients.

Discussion:

Our results may have implications for developing interventions to improve access and quality of care for patients from lower SES backgrounds, ultimately reducing disparities in orthopaedic surgery.
Coronal Alignment in Adult Spine Surgery
Authors: Sharfman Zachary T. , Clark Aaron J. , Gupta Munish C. , Theologis Alekos A.
Published: February 2024

Coronal realignment is an important goal in adult spine surgery that has been overshadowed by emphasis on the sagittal plane. As coronal malalignment drives considerable functional disability, a fundamental understanding of its clinical and radiographic evaluation and surgical techniques to prevent its development is of utmost importance. In this study, we review etiologies of coronal malalignment and their radiographic and clinical assessments, risk factors for and functional implications of postoperative coronal malalignment, and surgical strategies to optimize appropriate coronal realignment in adult spine surgery.
Energy Consumption and Substrate Utilization During Spinal Surgery
Authors: Zonshayn Samuel , Coppola Christina , Lawrence James P.
Published: February 2024

Introduction:

This study aims to measure surgeon physiologic stress and energy expenditure during adult spine surgery. Energy expenditures were assessed based on patient BMI, lead use, instrumentation/intraoperative navigation, primary/revision surgeries, tranexamic acid (TXA) use, and anatomic region involved.

Methods:

The senior author wore a heart rate (HR) monitor and triaxial accelerometer during spinal surgeries, providing assessments of mean HR, maximum HR, calories consumed/minute, and calories as measured by a Polar device (P calories) and Fitbit device (F calories).

Results:

One hundred sixty-two surgeries were included. Median patient age was 62 years. Median BMI was 29.02. Significant differences existed for BMI and estimated blood loss (P < 0.05). TXA use had a significant effect on case time, estimated blood loss, P calories, F calories, and Kcal/min (P < 0.05). Instrumentation use was significant for all variables (P < 0.05), except for mean HR and Kcal/min (P > 0.05). Lead use did not have a significant effect on max HR, P calories, F calories, and Kcal/min (P > 0.05). Navigation use was associated with significant differences for every variable tested (P ≤ 0.05). Differences were observed between primary and revision surgeries for case time, estimated blood loss, and F calories (P < 0.05).

Conclusions:

In spinal surgery, the use of navigation, instrumentation use, TXA use, and performing revision surgeries were associated with increased energy expenditure and can potentially increase surgeon fatigue.
Bilateral Os Trigonum Fracture Treated With Simultaneous Posterior Ankle Arthroscopy
Authors: Rungprai Chamnanni , Maneeprasopchoke Parinya , Steadman Jesse , Sripanich Yantarat , Suksintharanon Methasit
Published: February 2024

This is a case report of a 21-year-old female undergraduate student who sustained bilateral ankle injuries while jumping from a moving van wearing 3-inch high heel shoes. Upon initial presentation, her injury was treated conservatively as an acute bilateral ankle sprain for 6 weeks. However, the patient reported no improvement of pain and remained unable to self-ambulate. Bilateral MRI and CT scans of both ankles demonstrated bilateral os trigonum fractures. She underwent bilateral posterior ankle arthroscopic débridement of both os trigonum. At the postoperative 36-month follow-up, the patient reported notable improvement of all functional outcomes (36-item Short Form survey and Foot and Ankle Ability Measure), reported return to the same level of sports activities, and experienced no pain (visual analog scale) on either ankle. This is the first report in the literature of bilateral os trigonum fracture treated with simultaneous posterior ankle arthroscopic débridement.
Research on clay shear strength anisotropy at Šenkovec clay pit
Authors: Aniskin Aleksej , Kramarić Dalibor , Štuhec Damir , Moskalova Khrystyna
Published: February 2024

The paper deals with influence anisotropy to shear strength of clay and differences in test results of shear strength parameters, cohesion (c) and internal friction angle (φ) considering the direction of testing. Clay is very often the foundation soil of many buildings. There were performed three series of direct shear experiments for each of two different directions in relation to the horizontal, 0° and 90° (18 direct shear experiments in total). The results showed significant differences in the values of the shear strength parameters and to shear strength ultimately with considering to the test direction. Angle of internal friction (φ) is higher by 3.0° or 11.81% in the test at an angle of 0° in relation to the horizontal. A much more significant difference is visible in cohesion (c). The results showed that the cohesion (c) in the 90° test was higher by 14.92 kN/m² or 106.04%.
Giant dysgerminoma with pelvic metastases at the time of puberty: A case report and review of the literature
Authors: Medina Torres Lisbeth Andreina , Restrepo Becerra Andrés Darío
Published: February 2024

This study aims to provide a comprehensive insight into the clinical presentation, diagnostic challenges and management strategies associated with a rare occurrence of giant dysgerminoma with pelvic metastases in an adolescent patient. We intend to add valuable information to the medical literature that may help to better understand and manage similar cases in the future, making this case report potentially valuable to clinicians and researchers in the fields of gynaecological oncology and paediatric oncology. Germ cells, the precursors of the ova in women and sperm in men, can give rise to germ cell tumours if their migration goes wrong during embryogenesis. These tumours, which can be malignant or benign, are generally rare. In particular, germ cell lesions in women are usually benign, whereas in men they are often malignant. These tumours can present as intra- or extragonadal masses due to the migratory nature of the germ cells. Dysgerminoma, a rare malignant germ cell tumour, is more common in men than testicular seminoma. In women, dysgerminomas account for 1-2% of malignant ovarian tumours and present as exotic lesions. They are usually relatively small, but giant lesions have been reported. They also exhibit rapid growth and a characteristic lobulated surface, retaining the ovarian shape. Extra-ovarian presentations are rare but may extend into the abdominal region. In men, seminomas may occur extra-testicularly, particularly in the mediastinum. Dysgerminomas respond well to radiotherapy and chemotherapy, with survival rates of over 90% at five years with timely and appropriate treatment worldwide
Pseudothrombocytopenia due to platelet aggregates in an infant: A case report
Authors: Artunduaga-Cañas Esteban , Pineda Arias Esteban , Rivera Velásquez Estefania , Arango Duque Juan Sebastián , Rivera Villota Juan Diego , López Muñoz Diego Fernando
Published: February 2024

This case report describes the finding of EDTA-dependent Pseudothrombocytopenia in an 8-month-old infant, an extremely rare condition not reported in the literature. The patient presented with a fever due to insect bite and was diagnosed with abscessed cellulitis. A complete blood count showed a thrombocytopenia of 47 mil/L, with no history of bleeding or hematologic disease. The following day a new test was performed, which showed a platelet count of 214 mil/L, which was not consistent with the expected evolution of a real thrombocytopenia. Pseudothrombocytopenia was suspected and confirmed by observing platelet aggregates in the blood smear and upon recounting in a tube with sodium citrate, showed a normal value of 298 mil/L. Treatment consists of avoiding the use of EDTA as an anticoagulant and using other anticoagulants such as citrate or heparin. Timely identification of this phenomenon is essential to avoid diagnostic confusion and unnecessary or harmful treatment. This case brings to the scientific literature an example of EDTA-dependent Pseudothrombocytopenia in a pediatric patient, which can be easily confused with other causes of thrombocytopenia and requires a high index of clinical suspicion.