bluuebunny/crossref_metadata_2025 huggingface dataset:
Reciclagem de Componentes Eletronicos Aplicado a Robótica Educativa
Authors: López Villalba Faustino Ramón , Ramirez Aquino Antonia Thalia , Ibarrola Chamorro Claudia Raquel , López Gabriela
Published: May 2020

El cambio climático es un reto global que no tiene fronteras y que para combatirlo requiere del trabajo coordinado por parte de todos los estamentos de la sociedad. En este punto la educación se presenta como un factor preponderante en las diferentes propuestas que pueden hacerse, pues ofrece varias ciencias que pueden ayudar a resolver este problema desde varios ámbitos. El presente trabajo tiene como objetivo principal analizar e implementar un método eficiente para reutilizar y aumentar la vida útil de los distintos componentes electrónicos ayudando en el proceso de la prolongación de la vida útil de objetos creados por el hombre, y ajenos a la degradación que puede realizar la madre naturaleza.
Segmentation of Mammary Lesions in Ultrasound Images Applying Mask R-CNN
Authors: Ibarrola Chamorro Claudia Raquel , Pereira Wagner Coelho de Albuquerque
Published: May 2020

Breast cancer is the most frequent malignant tumor in women and one of the most common in the world. One of the most important issues in this condition is early detection. Computer-aided diagnostic (CAD) systems are objects of research, aiming to provide a second opinion to the health professional. A fundamental aspect within the CAD system is the segmentation of the lesion, allowing an adequate extraction of the lesion characteristics. The use of a computerized segmentation method helps eliminate human variability and, consequently, improve the performance of the lesion classifier. Convolutional Neural Networks (CNNs) are being used in segmentation problems, such as various types of medical imaging, people and road signs detection, for example. So inspired by these promissing results, the present work has as main objective to analyze and implement the Mask R-CNN as a tool of segmentation of mammary lesions in images obtained by ultrasound, to propose an efficient method of segmentation, aiding in the classification process of the CAD systems.
Technical Experiences on a Microservices-oriented Transformation using Open Source Software
Authors: Benitez-Davalos Walter , López-Pires Fabio , Cabañas David , Bogado-Sarubbi Yessica
Published: May 2020

Adopting emerging computing paradigms such as cloud applications include challenges associated to transform legacy software to essential characteristics of the mentioned computing model, e.g. on-demand self-service, broad network access, resource pooling, rapid elasticity and measured services. This paper presents a summary of technical experiences on applying one of the most popular approaches to address transformation of legacy software to cloud-native applications: a microservice-oriented architecture with connections to legacy systems through anti-corruption layers. Several technical considerations are presented, focusing on Open Source Software to include particular features on modern development practices as well as solving issues related to the cloud-native transformation.
The Concept of Cure in Thyroid Diseases
Authors: Azizi Fereidoun
Published: May 2020

: “Cure” has been referred to maintaining a healthy situation before the occurrence of the illness. With emerging non-communicable chronic diseases, many treatment approaches and management of these disorders have been found to control the disease, despite the fact that the status of the human body does not return to like it was before the illness. Patients become asymptomatic, but their body composition, cellular, and humoral factors differ from healthy individuals. In this article, it has been discussed that after treatment of thyroid diseases, only in few conditions the status of thyroid returns to the healthy situation after discontinuation of therapy and majority of thyroid illnesses are managed as “controlled”, meaning that patients become asymptomatic. However, their thyroid structure, function, and biochemical factors fundamentally change. Therefore, patients may need additional permanent treatment to attain euthyroidism and especial follow-up for recurrence of the disease. For example, for Graves’ hyperthyroidism, all three forms of therapeutic approaches fail to re-establish continuous normal thyroid function in all patients. Long-term anti-thyroid drug therapy appears to cause an increase in the number of patients with Graves’ disease to attain a cure without further treatment.
Compare and despair or compare and explore? Instagram social comparisons of ability and opinion predict adolescent identity development
Authors: Noon Edward John
Published: May 2020

Whilst there is an emerging literature concerning social comparisons on social networking sites (SNSs), very little is known about the extent to which such behaviours inform adolescent identity. Drawing upon the three-factor model of identity development (Crocetti, Rubini & Meeus, 2008), this study seeks to determine the relationship between Instagram comparisons of ability and opinion and three identity processes: commitment, in-depth exploration, and reconsideration of commitment. 177 British adolescents responded to a paper survey (Mage = 15.45; Female, 54.8%) between December 2018 and February 2019. Instagram social comparisons of ability were positively associated with commitment and in-depth exploration, whilst their relationship with reconsideration of commitment was moderated by gender. In contrast, Instagram social comparisons of opinion were positively related with in-depth exploration and reconsideration of commitment. Findings suggest that although both forms of social comparison behaviour may evoke adolescents to explore their identity, Instagram social comparisons of ability may have less maladaptive identity implications for adolescent males.
The Rich Young Ruler and Christian Ethics
Authors: McKenny Gerald ,   Philosophy Documentation Center
Published: May 2020

In Christian ethics the Gospel story of the encounter of a rich young ruler with Jesus has been interpreted in two major ways: one that treats Jesus’ directive to the ruler as a counsel that goes beyond the commandments the ruler claims to have kept, and another that treats the directive as contained in the commandments and exposing his failure to keep them. I reconstruct Calvin’s version of the second interpretation, contrast it with Aquinas’s version of the first, and point out some problems with it. I then formulate a revised version that avoids the problems and amounts to a promising alternative for Christian ethics.
Precarização e privatização das políticas públicas na educação a distância
Authors: Mattos Miriam De Cassia do Carmo Mascarenhas , Silva Maria Cristina Rosa Fonseca da
Published: May 2020

Estudo doutoral bibliográfico que contextualiza as políticas públicas no âmbito da educação e da EAD, refletindo sobre suas privatizações. Apresenta alguns estudos em nível internacional e relaciona os mesmos com as políticas no Brasil que se direcionam para a desresponsabilização do Estado. O financiamento da educação superior vem estimulando medidas que acentuam a privatização interna das instituições, ao mesmo tempo em que aprofunda o processo de empresariamento da educação superior, por meio da ampliação do número de cursos privados. Como exemplo, descreve e analisa o caso do grupo Kroton educacional, maior empresa na área em nível mundial e no ramo da EAD no Brasil. Seus resultados mostram que as políticas públicas educacionais têm favorecido as grandes empresas, que vêm lucrando ainda mais com a precarização da educação. Conclui que as mais recentes políticas de flexibilização vêm para favorecer o crescimento da EAD no Brasil, que pode ganhar um fortalecimento com o oferecimento do ensino médio nesta modalidade, aprovado recentemente, marcando assim uma conjuntura neoconservadora e de mercantilização da educação.
Interdisciplinaridade e Educação na perspectiva de uma pedagogia hermenêutica
Authors: Boufleuer José Pedro , Moura Leandro Renner de
Published: May 2020

Este ensaio visa enfrentar o tema da interdisciplinaridade na educação baseando-se na filosofia hermenêutica de Hans-Georg Gadamer (2012). A motivação do estudo tem a ver com o modo como a interdisciplinaridade vem sendo recepcionada nos espaços de formação humana e com os pressupostos que, nem sempre problematizados, sustentam este conceito no âmbito das práticas pedagógicas. Proliferou-se nas últimas décadas a noção de que a interdisciplinaridade representa o modo prático pelo qual a educação escolar responderia à crescente desarticulação temática das áreas do conhecimento. Este contraponto, no entanto, age em perspectiva técnica e sob um tipo de racionalidade que obscurece a experiência da vida humana com o conhecimento. Por essa razão, o propósito desta reflexão é indicar outro horizonte de compreensão que reitera o esforço retrospectivo da hermenêutica para recobrar a unidade da vida nos processos de comunicação e de aprendizagem dos conhecimentos. Inicialmente, a fim de observar como a interdisciplinaridade adquiriu lugar no debate teórico e na legislação educacional brasileira, realiza-se uma checagem virtual nos Parâmetros Curriculares Nacionais (PCNS, 1997; 1998) com o intuito de destacar as variações de sentido mais evidentes. Em seguida, busca-se nos pressupostos da hermenêutica filosófica a tematização do mundo humano pela linguagem e a recuperação do diálogo como experiência fundante da constituição do mundo humano. Por fim, a pesquisa propõe os desdobramentos de uma concepção hermenêutica da interdisciplinaridade na esteira do diálogo gadameriano, sendo neste horizonte teórico que o presente ensaio situa a interdisciplinaridade nos processos de formação humana.
Avaliação da arborização urbana da Cidade de Manaus por seus residentes
Authors: Lins Neto Nelson Felipe de Albuquerque , Souza Paulo Roberto Pires de , Viana Álefe Lopes , Mari Maikel Lamego Guimarães , Medeiros Suzana Helen da Silva
Published: May 2020

The aim of this study was to quantify the perception of afforestation in the city of Manaus by their residents and it relates to investments made by the municipal government. Data were obtained from 647 online electronic questionnaires distributed among users of social networks on the internet and smartphones. The results indicated that only 3% of participants considered very good afforestation in Manaus and 42% very poor, and the north and east areas with 48% to 61% the worst of the city. As for the benefits of afforestation, 72% indicated thermal comfort as the most important. The biggest concern was the risk of tipping, followed by interference power grid, with 25 and 24%, respectively. The most remembered species were pau pretinho, ipê and fruit trees. Of the respondents, only 65% would be willing to contribute whit some value for afforestation, even with 71% of those considering the insufficient public investments for expansion and maintenance of green spaces. When compared to cities like São Paulo and Campo Grande items as a percentage of GDP invested in municipal afforestation , R$/km2 and R$/capita , were always lower.
Monitoramento de variáveis microbiológicas para avaliação da balneabilidade de uma praia do Norte Catarinense
Authors: Baucke Alex Sandro , Zambão Patrícia Hüther , Serbent Maria Pilar
Published: May 2020

The human actions arising from influx of visitors in coastal regions may be associated to public health problems and negative effects to the environment. In this sense, microbiological analysis of water samples were developed on a beach in north Santa Catarina, located in the municipality of Penha. To verify the sea water for contact primary to recreation and to have a monitoring data basis, the considerations made by environmental agency of State of Santa Catarina were analyzed complementarily. The study happened in November of 2014 and January/ March of 2015. The water collection it occurred on eight points along the Penha’s Beach. The points are salty water (sea) and wastewater disposal on the sand. Throughout the study, microbiological contamination was observed due to the presence of Escherichia coli, an important indicator of fecal contamination, in the places where sampling of the water and exposed wastewater at the edge of the beach were performed. The results obtained showed discrepancy in values of E. coli between points and collected periods. Thus, it is suggested the need for a larger number of samples for monitoring water quality, especially at the time with great flow of tourists in order to avoid problems of public health as a water borne diseases. Finally, it is understood that this work can not characterize properly the bathing conditions, due to the short period of study. However, the joint work of environmental agencies and universities may lead to better information regarding bathing conditions at coastal areas available to the public.
Avaliação dos Componentes de Rendimento do Trigo quando Submetido a Diferentes Fontes de Nitrogênio
Authors: Camponogara Alexandre Da Silveira , Oliveira Gislayne Alves , Georgin Jordana , Rosa Ana Lúcia Denardin da
Published: May 2020

This study aimed to evaluate the effects of applying different nitrogen sources in the states of booting and silking on yield components and the wheat crop productivity (Triticum aestivum L., Quartz - OR Seeds). The experiment was conducted in Frederico Westphalen-RS. The experimental design was a randomized complete block design, with eight treatments and four replications. The treatments consisted of combinations of different sources and forms of N application that follow: T1 - control (no N), T2 - Fertilization base + urea, T3 - Basic fertilization + ammonium nitrate, T4 - Fertilizing base + urea + foliar nitrogen, T5 - Basic fertilization + ammonium nitrate + foliar nitrogen, T6 - Basic fertilization + foliar nitrogen, T7 - Basic fertilization + urea + ammonium nitrate and T8 - Basic fertilization + ammonium nitrate + urea. The ammonium nitrate application associated with the supplemental foliar N resulted in an increase in grain yield of 51.5% over the control to the control. Other income components also obtained average with significant magnitudes verified by Duncan test at 5% error probability.
A sustentabilidade e o desenvolvimento sustentável na educação em engenharia
Authors: Loureiro Solange Maria , Pereira Vera Lúcia Duarte do Valle , Pacheco Júnior Waldemar
Published: May 2020

One of the challenges of this century is related to the perspective that the societies become socially, environmentally and economically sustainable in order to satisfy the needs of present generations without reducing the chances of the future generations to achieve theirs. It is through higher education that new professionals start acting, thus, influence how current and future generations deal with the social, environmental and economic issues, i.e., with the sustainability and the Sustainable Development (SD). So, it is responsibility of higher education to provide to the people competencies to enable them to deal with the technical and environmental challenges through solutions that minimize environmental impacts and social inequalities. As the engineers have direct relationship to the production of knowledge and technologies that directly impact society and the environment is essential that the engineering background allows them to design technologies and economic activities to sustain rather than degrade the natural environment and improve health and human well-being. In this context, this paper aims to reflect about the vision of sustainability/DS required for engineering education so that it may contribute to make sustainable societies.
Geração e gerenciamento dos resíduos sólidos em uma oficina mecânica
Authors: Lima Michael Bruno Oliveira de , Viana Ednilson
Published: May 2020

Numbers show how important is a mechanical workshop, it is one of the main economics activities of Brazil´s services sector. Due this big quantity and the type of work, we can say that this kind of firm are a big generating of solid waste, and the most important, some of this waste have a large amount of toxic compounds. Therefore, the management and the discard must be done correctly, so there is no effect in the employee´s health and do not contaminate the environment. This work has analyzed a study in one case in Vila Mariana, São Paulo-SP, to diagnose measure and quantify the generation of this waste and your management in a small workshop. After the identification of the wastes they were classified after NBR-10.004 da ABNT, with the purpose of make it easier to analysis. It can be observed a several mistakes in the management of this workshop, in all of the stages, collection, handling, storage, transportation and final discard. It was observed that the management of the wastes is ineffective and problematic, and must be improved through more sector agreements, given the necessary importance for the correct management.
Uso do índice RDE para determinação de anomalias de drenagem no Rio Capibaribe (PE)
Authors: Silva Rubens Neves e , Gomes Daniel Dantas Moreira , Lima Carlos Eduardo Santos de , Goldfarb Mauricio Costa
Published: May 2020

The longitudinal profile of a river is the Cartesian representation of the relationship between its height and its length. This relationship has been used as an important element for geomorphological and hydrological studies; example studies to determine the drainage anomalies. This study aimed to the determination and classification of river Capibaribe (PE) drainage anomalies. The analysis was made from the longitudinal profile of the Capibaribe river, built with the help of Google Earth software, through the RDE index proposed by Hack (1973). The longitudinal profile of the Capibaribe river is relatively balanced and contains anomalies second and first order. This profile presented an atypical geometry stretches in between kilometers 100 and 150, 150 and 200 and 200 and 250 due to the increase of the slope in the direction from upstream to downstream, as the literature indicates that in a typical profile should decrease in the slopes towards the mouth.
Remoção do herbicida glifosato utilizando carvão ativado impregnado com compostos metálicos de prata e cobre para a melhoria da qualidade da água
Authors: Rubio Andressa Jenifer , Bergamasco Rosângela , Yamaguchi Natália Ueda
Published: May 2020

With the increasing use of several pesticides in agriculture, including the Glyphosate which is the herbicide most widely consumed worldwide, there is a need for the development of diversified and effective water treatment, since glyphosate consumption can cause serious health problems on animals, humans and plants. As an alternative treatment, the removal of glyphosate from the water can be obtained with the use of activated carbon, and further to leverage its results, may be used the impregnation of silver and copper on the activated carbon, since the activated carbon in the purest form it is marketed often not sufficiently effective for removing some pollutants. Therefore, this study aimed at the removal of glyphosate by an adsorption process using activated carbon impregnated with 0.5% silver and 0.5% copper with the aim of increasing the adsorption efficiency when compared to activated carbon. It was observed that the removal of glyphosate is improved when using the impregnated metal compounds, being 66.1% with the adsorbent GAC / AgCu and only 21.1% with GAC. It is still needed profound research related to characterization and adsorption experiments to better explain the adsorption mechanism that occurs in this process. However, it can be concluded that the granular activated carbon soaked with 0.5% silver and copper developed in the present work may be named as a possible technology for improving the quality of water intended for human consumption for removal of the glyphosate herbicide.
Avaliação dos impactos socioambientais urbanos: o descarte incorreto dos resíduos e atividade de conscientização ambiental na cidade de Apodi - RN
Authors: Morais Adriano Erik Reinaldo de , Barbosa Plinio Tavares , Alves Leonardo Alcântara
Published: May 2020

The emergence of new technologies results in the growth of industries and population growth in urban centers. Coupled to this growth comes the problem of waste, these that turned into serious urban problems, often with a costly and complex management. Due to the shortage of areas for disposal, waste is directly linked to the quality of life of a society. The amount of waste produced by a population depends on a number of factors such as income, time of year, way of life. Even considered a small town, Apodi presents a significant growth in its production of household waste, and there was a correct destination for them, comes a series of environmental problems such as: aesthetic, health and environment in the city. Discussions on this issue seeks to answer what the possible environmental impacts caused by these deficiencies household waste and environmental sanitation instruments in the affected population. However, this paper aims to propose awareness studies of environmental impacts arising from the incorrect disposal of household waste in the city of Apodi - RN, through research carried out and to identify the problems faced by the population of the city.
Consciência e Atitude Ambiental em Estudantes de Instituições de Ensino Técnico e Tecnológico
Authors: Teixeira Linnik Israel Lima , Silva Filho José Carlos Lázaro , Meireles Fernanda Rosalina da Silva
Published: May 2020

Environmental education is a powerful tool for forming collective environmental awareness from primary school to higher education level. Based on this, this study aims to investigate environmental awareness and environmental behavior among students of a technological educational institution. Using the NEP Scale (Dunlap et al., 2010) through a questionnaire with students it sought to examine the relationship between consciousness and environmental behavior through variables like course, semester, gender and environmental education. The final data generated can be divided into two outcomes: a) environmental awareness, was not observed significant differences between the courses and also for the semesters of respondents. On the other hand, significantly higher levels of environmental awareness were found in women and students who studied environmental education before they enter higher education; b) the environmental behaviour, the highest levels of pro-environmental behavior were found in students of Environmental Engineering, the graduates, on women and college students who studied environmental education before starting higher education. The study results show compliance with other research and suggest area researchers a deepening of the factors that influence these results.
Análise da arquitetura tumular do cemitério jardim municipal de Maringá, Estado do Paraná
Authors: Martim Aline Giseli , Angelis Bruno Luiz Domingos de , Angelis Neto Generoso De , Silva Frederico Fonseca da
Published: May 2020

Based on the assumption that the burial of bodies and their subsequent decomposition into horizontal cemeteries can potentially cause contamination of groundwater, this paper aims to analyze the structural characteristics of the tombs and the tombs of architecture Garden Municipal Cemetery of Maringa, located in the Parana State (Brazil), from the identification of different types of architecture. Thus, the preparation of this article was focus on compliance with Municipal Decree no 100/1984 and no 1475/2002 approving the Regulation of Garden City Cemetery, in addition to regulating the coating and reconstructions of tombs in the same.
Caracterização do consumo de carne suína da população de Xanxerê, Santa Catarina, Brasil
Authors: Kirinus Jackeline Karsten , Benedetti Matheus , Pavlik Willian , Taffarel Gustavo Vinicius , Belmonte Camila De Oliveira , Dörr Andrea Cristina , Téo Ander Renã
Published: May 2020

The swine stands out in some regions of Brazil and more specifically, in Santa Catarina, mainly by having national leadership in the slaughter of these animals. This study constitutes a very important tool, since the identification of the main consumed cuts and analysis of what it means meat with high quality for the consumer Xanxerense, will identify the user profile and contribute to the production system products meat. Field research with primary data collection using forms applied to pork consumers Xanxerê was used. Of the interviewed, 93.3% reported consuming pork meat. Moreover, it was observed that most of the people receive a personal or family income 2-5 the minimum wage in real. The rib was the main cutting preference. Further, it was found that the clear appearance and visible fa t are features that influence the high degree of quality of pork meat for men and women, respectively. Therefore, it is necessary to invest in actions that demonstrate the socio-economic factors involved in the consumption of pork, as well as studies that analyze the quality of the product and the real environmental impact with its production.
Reuse of glass in concrete: a study of the production and mechanical performance of resistance
Authors: Paz Lidiane Andrade Fonseca da , Santos Vando Dias dos
Published: May 2020

The glass incorporated into the concrete contributes to the conservation of the environment, as it will have a correct destination and is an easily found material. This work had the objective of analyzing the mechanical performance of the concrete produced with glass waste from non-returnable packaging. Since glass is a residue that is easily found, it is justified to incorporate it into concrete in partial replacement of small aggregates, thus avoiding its disposal inlandfills and also in an irregular way. The concrete produced was made with the addition of “51” and “Long Neck” ground glass. A standard trace of 25 MPa was defined, with partial substitutions of 5%, 15%, 25% and 35% in the small aggregate. The individual strengths of the test specimens were submitted to the Tukey test for statistical analysis and it was verified that the trait with the percentage of 35% substitution is statistically different from the other traits. The concrete had a mean Fck of 32,37 MPa, higher than the established minimum of 25 MPa. It can be concluded that theconcrete with the use of ground glass presents technical feasibility for execution and contributes to the preservation of the environment.
A new raw material in the production of biodiesel: purple pinion seeds.
Authors: Fonseca Aluísio Marques da , Carmo Margareta Do , Colares Regilany Paulo , Valle Camila Peixoto do , Oliveira Sara Jane de , Alcócer Juan Carlos Alvarado , Pinto Olienaide Ribeiro de Oliveira , Santos José Cleiton Sousa dos , Sousa Emerson Yvay Almeida de , Silva Francisco Felipe Maia da
Published: May 2020

Biodiesel is an alternative fuel that is produced through oil plants or animal fat. It is a renewable energy source, with biodegradable characteristics, to emit less pollutant than diesel. Thus, this work aims to show the production of biodiesel from the purple-pinion (Jatropha gossypiifolia L.) seeds. In addition to the synthesis, the physical-chemical characterization of both the raw material and the final product was carried out. The biodiesel synthetic route was performed by the basic catalytic transesterification reaction, using potassium hydroxide (KOH) in the presence of methanol (CH3OH) in the molar ratio of 1: 3 (oil: methanol). As a result, it was observed that the mass conversion of the biodiesel was 22.05 g. The physical-chemical analyzes carried out were acid index of 0.106 mgKOH / g, according to ANP technical resolution. The peroxide index of 1.03 meqO2 / kg, the kinematic viscosity of 20 ° C to 40 ° C, obtained was 6.455 mm2/s and 3.5343 mm2/s, the values are close to the ANP technique resolutions. Stability was 0.26 hours, and the biodiesel burning test was executed for approximately 3 hours. Therefore, there is a high viability of biodiesel production through the purple pinion seeds.
Water balance and net radiation in forest and pasture area in Southwest Amazon
Authors: Ruezzene Camila Bermond , Parizotto Denise , Cidin Ana Carolina , Pinto Thandy Junio da Silva , Oliveira Dayane De , Crestana Silvio , Miranda Renato Billia de , Mauad Frederico Fábio
Published: May 2020

Energy availability has direct influence over hydrological cycle, climate and preciptation. The determination of net radiation balance (Rn) and the spacial and temporal recognition of water availability allow establishing guidelines and planning the implementation of public resource management policies. The objective of this study was to analyze the water balance and net radiation balance of the year 2017 at two experimental sites in the state of Rondônia (RO), Brazil: an Amazon rainforest area located in the Jaru Biological Reserve (REBIO) and a pasture area (FNS) located in the municipality of Ouro Preto d’Oeste, near the forest área. The data were obtained from the REBIO climatological station, in the municipality of Ji-Paraná-RO, belonging to the experimental sites. Calculations for evapotranspiration potential were based on Thornthwaite and Mather’s method. The "Eddy Covariance" method was used to obtain the radiation balance. The forest system presented greater energy availability in the rainy season and higher evapotranspiration balance when compared to the pasture area. Water balance extract analysis pointed to water stress in pasture area, opposite to the forest area, which indicates that conversion of native forest to pasture is a process capable to compromise the availability of water resources and alter climatic aspects.
Analysis of the Effects of the Housing Foundation Activities on Economic and Environmental Development of Rural Settlements: A Case Study of Moghan (Germi) County Villages
Authors: Kalansara Firouz Mahdizadeh , Jahani Mahdi , Ahmadian Mohammad Ali
Published: May 2020

The Islamic Revolution Housing Foundation was established as the first executive body of the country in 1979 with the aim of helping the construction of housing for the deprived. Later, conductive (Hadi) plan preparation, conductive plan execution and the issuance of ownership document were added to the duties of the Foundation. Case studies are needed in order to understand the quality of the topics and the results of preparation and implementation of these plans. Accordingly, in this research, conductive plans, rural housing plans and eligible rural ownership documents in Moghan (Germi) County villages have been addressed. These plans have been implemented in 55 villages of the county. Thus, in the present study, we have investigated the effects of the Housing Foundation activities on economic and environmental development of Germi County villages. Here, a descriptive-analytical method based on documentary studies and field operations (questionnaire, interview, etc.) has been employed. Given the number of villages and the high number of households living in the villages, a sample size of 287 households was determined using Cochran formula and was distributed among the households in each village based on a systematic random sampling method. The research result based on the correlation coefficient test demonstrates that there is no significant relationship between the Housing Foundation activities and economic development of villages (p-value> 0.05). Therefore, the research hypothesis is rejected at a 95% confidence level. Further, the relationship between the Housing Foundation activities and environmental development of villages is not significant (p-value> 0.05). Hence, the hypothesis is rejected at a 95% confidence level.
Decolorization and degradation of methylene blue by photo-Fenton reaction under visible light using an iron-rich clay as catalyst: CCD-RSM design and LC-MS technique
Authors: Zimmermann Bárbara Machado , Peres Enrique Chaves , Dotto Guilherme Luiz , Foletto Edson Luiz
Published: May 2020

In this work, an iron-rich bentonite was thermally modified at 200 oC and posteriorly used as a heterogeneous catalyst in the decolorization and degradation of methylene blue dye (MB) by photo-Fenton reaction under visible irradiation. The variables such as catalyst concentration and pH were investigated in the reaction system to detect the optimal decolorization conditions using the response surface methodology (RSM) coupled with Central Composite Design (CCD). Photodegradation of MB was analyzed by LC-MS technique. The results indicated that the optimal conditions to obtain 94% of MB decolorization efficiency were pH = 2.4 and catalyst mass = 0.02 g. It was also possible to verify that the simultaneous combination of catalyst, hydrogen peroxide and visible light in the reaction medium was primordial for the increasing MB decolorization efficiency. MB degradation occurred partially at 180 min of photo-Fenton reaction, since the presence of dye in the solution was reduced, leading to its transformation into different intermediate products. Therefore, the catalyst used in this work has demonstrated a great potential for the degradation of cationic dye, allowing its use in advanced oxidation processes
Environmental knowledge level in undergraduate students: University of San Pedro, Peru
Authors: TauccayaI Oscar Julián Berrios , Reyes David Ricse , More Leandro Vallejos , Mendoza Prospero Cristhian Onofre Zapata
Published: May 2020

Studies specifically referring to the evaluation of learning levels and awareness of university students in environmental matters are incipient. In that order, the objective of this research is to establish the influence curriculum of the San Pedro University, Sullana subsidiary on the level of environmental knowledge of undergraduate students, 2017. The research design is non-experimental, applicative, observational and descriptive. The study population corresponds to undergraduate students of the San Pedro University, Sullana, 2018. The total population comprises 2050 students; the sample is structured by a non-probabilistic sample, represented by 188 undergraduate students of the San Pedro University Sullana 2017, students from different Professional Schools. The survey technique was applied, through a knowledge assessment questionnaire on environmental issues. With a significance level of 0.05, it was demonstrated that the Study Plan of the San Pedro University subsidiary Sullana 2017 doesn’t have any significant influence on the level of environmental knowledge of undergraduate students. With an average of 2.73% of the courses dedicated to the environmental issue, it is concluded that environmental issues are not a priority within the curricular contents of the San Pedro University, Sullana subsidiary.
Use of statistical control charts for monitoring the quality of flour
Authors: Tekić Dragana , Mutavdžić Beba , Novaković Tihomir
Published: May 2020

The use of statistical quality control in the production and storage processes significantly enhances the overall quality of products. Although various techniques are used for quality monitoring purposes, control charts are considered of paramount importance. In this paper, the ash and moisture contents of the wheat flour type 500 were analyzed using descriptive statistics. Consequently, the control charts for the variations in and the mean values of the parameters considered were created. The control charts obtained for the mean parameter values show that the flour production process was in control relative to both parameters considered, exhibiting only random variations. However, the control charts obtained for the variability in the parameter values considered show special variations, the causes of which require further research in order to maintain the satisfactory quality of flour production.
Fornuftens fyrtårn. Om Jürgen Habermas: Auch eine Geschichte der Philosophie,
Authors: Albinus Lars
Published: May 2020

Anmeldelse og diskussion af Jürgen Habermas, Auch eine Geschichte der Philosophie, Band 1: Die okzidentale Konstellation von Glauben und Wissen, Band 2: Vernünftige Freiheit. Spuren des Diskurses über Glauben und Wissen, Suhrkamp 2019
Propiedad intelectual y legislación internacional
Authors: Ferrándiz Pablo
Published: May 2020

Pablo Ferrándiz, abogado especialista en propiedad intelectual, describe en este artículo las distintas situaciones legales que se derivan de la publicación de obras intelectuales en Internet, teniendo en cuenta la globalidad del medio e intercediendo en favor de la construcción de una legislación internacional.
Cybersecurity law of the People’s Republic of China as a key instrument for ensuring information security of the banking and finance system
Authors: Gorian Ella
Published: May 2020

The object of this research is the legal relations that emerge in ensuring informations security of the banking and finance system of the People’s Republic of China. The work characterizes China’s cybersecurity law, which was enacted in 2017. The author determines the key positions of this statutory act that establishes the foundation for national institutional and normative-legislative mechanism of ensuring information security of the banking and finance sectors as objects of critical information infrastructure. China’s cybersecurity law represents a fundamental piece of legislation that defines the principles, mechanisms and order of ensuring information security. It defines critical information infrastructure through nomenclature of the sectors and indication of criteria for designation of one or another sector as critical information infrastructure. The banking and finance sector meets such criteria, thus ensuring its information security is based on the general positions of this legislation. The law determines the regime of protection of personal data, as well as obligations of network carriers that are included into the institutional mechanism of provision of cybersecurity. All aforementioned facts make China’s cybersecurity law a key legislative instrument of the mechanism of ensuring information security of the banking and finance system.
Identification of a novel toxicophore in anti-cancer chemotherapeutics that targets mitochondrial respiratory complex I
Authors: Stephenson Zoe A , Harvey Robert F , Pryde Kenneth R , Mistry Sarah , Hardy Rachel E , Serreli Riccardo , Chung Injae , Allen Timothy EH , Stoneley Mark , MacFarlane Marion , Fischer Peter M , Hirst Judy , Kellam Barrie , Willis Anne E
Published: May 2020

Disruption of mitochondrial function selectively targets tumour cells that are dependent on oxidative phosphorylation. However, due to their high energy demands, cardiac cells are disproportionately targeted by mitochondrial toxins resulting in a loss of cardiac function. An analysis of the effects of mubritinib on cardiac cells showed that this drug did not inhibit HER2 as reported, but directly inhibits mitochondrial respiratory complex I, reducing cardiac-cell beat rate, with prolonged exposure resulting in cell death. We used a library of chemical variants of mubritinib and showed that modifying the 1H-1,2,3-triazole altered complex I inhibition, identifying the heterocyclic 1,3-nitrogen motif as the toxicophore. The same toxicophore is present in a second anti-cancer therapeutic carboxyamidotriazole (CAI) and we demonstrate that CAI also functions through complex I inhibition, mediated by the toxicophore. Complex I inhibition is directly linked to anti-cancer cell activity, with toxicophore modification ablating the desired effects of these compounds on cancer cell proliferation and apoptosis.
The Influence of Perceived Security and Perceived Enjoyment on Intention To Use with Attitude Towards Use as Intervening Variable on Mobile Payment Customer in Surabaya
Authors: Sudono Fabrianne Setiawati , Adiwijaya Michael , Siagian Hotlan
Published: May 2020

This study aims to determine the effect of perceived security and perceived enjoyment as moderated variable on intention to use mobile payment, either directly or through mediation of attitude towards use. The method used in this study is quantitative by spreading the questionnaires to 211 respondents of mobile payment application users both online and offline in Surabaya. The selection of this research sample used a judgment sampling technique with criteria determined by the researcher. The data was analyzed with Structural Equation Modeling (SEM), SmartPLS tools. The questionnaire collected was 192 questionnaires. The results show that perceived security and perceived enjoyment have a significant directly influence on intention to use and indirectly through mediating attitudes to use mobile payment. In addition, it was found that perceived enjoyment variable moderated the relationship between perceived security and attitudes to use but did not moderate the relationship between perceived security and intention to use.
Is Green Concept in Residential Expensive?
Authors: Widyanto Denny Stevanus , Budiman Januar , Anastasia Njo
Published: May 2020

A house, especially landed housing is one of the primary needs and yet scarcity continues to occur due to the depletion of land quantity and increasingly rising selling prices. In order for the development of a residential area to be more directed and productive, it is necessary to analyze the appropriate land allocation and generate maximum land value. Through this paper, the author examines the effect of a residential planning with green concepts along with housing support facilities in relevance with highest and best use analysis, especially its impact on costs and revenues.
A digital mRNA expression signature to classify challenging Spitzoid melanocytic neoplasms
Authors: Hillen Lisa M. , Geybels Milan S. , Spassova Ivelina , Becker Jürgen C. , Gambichler Thilo , Garmyn Marjan , zur Hausen Axel , van den Oord Joost , Winnepenninckx Véronique
Published: May 2020

Spitzoid neoplasms are a challenging group of cutaneous melanocytic proliferations. They are characterized by epithelioid and/or spindle‐shaped melanocytes and classified as benign Spitz nevi (SN), atypical Spitz tumors (AST), or malignant Spitz tumors (MST). The intermediate AST category represents a diagnostically challenging group since on purely histopathological grounds, their benign or malignant character remains unpredictable. This results in uncertainties in patient treatment and prognosis. The molecular properties of Spitzoid lesions, especially their transcriptomic landscape, remain poorly understood, and genomic alterations in melanoma‐associated oncogenes are typically absent. The aim of this study was to characterize their transcriptome with digital mRNA expression profiling. Formalin‐fixed paraffin‐embedded samples (including 27 SN, 10 AST, and 14 MST) were analyzed using the NanoString nCounter PanCancer Pathways Panel. The number of significantly differentially expressed genes in SN vs. MST, SN vs. AST, and AST vs. MST was 68, 167, and 18, respectively. Gene set enrichment analysis revealed upregulation of pathways related to epithelial–mesenchymal transition and immunomodulatory‐, angiogenesis‐, hormonal‐, and myogenesis‐associated processes in AST and MST. A molecular signature of SN vs. MST was discovered based on the top‐ranked most informative genes: NRAS, NF1, BMP2, EIF2B4, IFNA17, and FZD9. The AST samples showed intermediate levels of the identified signature. This implies that the gene signature can potentially be used to distinguish high‐grade from low‐grade AST with a larger study cohort in the future. This combined histopathological and transcriptomic methodology is promising for prospective diagnostics of Spitzoid neoplasms and patient management in dermatological oncology.
CSF and serum ferritin levels in narcolepsy type 1 comorbid with restless legs syndrome
Authors: Barateau Lucie , Chenini Sofiene , Lotierzo Manuela , Rassu Anna Laura , Evangelista Elisa , Lopez Régis , Gorce Dupuy Anne‐Marie , Jaussent Isabelle , Dauvilliers Yves
Published: May 2020

Objectives

To investigate whether cerebrospinal fluid (CSF) and serum ferritin levels differ between patients with narcolepsy type 1 (NT1) comorbid with restless legs syndrome (RLS) or periodic leg movements during sleep (PLMS), and patients with NT1 or controls without comorbid RLS or PLMS.

Methods

Sixty‐six drug‐free patients with NT1 (44 males, age 38.5 years [14–81]) were enrolled, including 20 with RLS, 18 with PLMS index ≥15/h (six with both RLS and PLMS). Thirty‐eight drug‐free patients (12 males, age 22.5 years [12–61]) referred for sleepiness complaint, but without central hypersomnia, RLS, PLMS were included as controls. Clinical, electrophysiological and biological (CSF/serum ferritin, orexin [ORX]) data were quantified.

Results

NT1 patients with and without RLS did not differ for age, gender, and body mass index (BMI). No between‐group differences were found for CSF ferritin, ORX, and serum ferritin levels. No CSF ferritin, ORX, and serum ferritin level differences were found between NT1 patients with and without PLMS, or with RLS or PLMS versus not. CSF‐ferritin levels were not different between NT1 and controls in adjusted analyses. CSF‐ferritin levels in the whole population correlated positively with age, serum‐ferritin, BMI, negatively with ORX, but not with PLMS index. In NT1, CSF‐ferritin levels correlated with age and serum‐ferritin but not with PLMS.

Conclusion

The absence of CSF ferritin deficiency in NT1 with comorbid RLS or PLMS indicates normal brain iron levels in that condition. This result suggests that the frequent association between RLS, PLMS, and NT1 is not based on alterations in brain iron metabolism, a pathophysiological mechanism involved in primary RLS.
Treatment With Mycophenolate and Cyclophosphamide Leads to Clinically Meaningful Improvements in Patient‐Reported Outcomes in Scleroderma Lung Disease: Results of Scleroderma Lung Study II
Authors: Volkmann Elizabeth R. , Tashkin Donald P. , LeClair Holly , Roth Michael D. , Kim Grace , Goldin Jonathan , Clements Philip J. , Furst Daniel E. , Khanna Dinesh
Published: May 2020

Objective

Our objective was to determine if treatment with cyclophosphamide (CYC) and mycophenolate mofetil (MMF) improves patient‐reported outcomes (PROs) among patients with systemic sclerosis‐related interstitial lung disease (SSc‐ILD).

Methods

This study examined PROs in patients with SSc‐ILD (N = 142) who participated in the Scleroderma Lung Study II, a randomized controlled trial comparing MMF for 2 years with oral CYC for 1 year followed by 1 year of a placebo. Joint models were created to evaluate the course of PROs over 2 years. The difference in PRO scores from baseline to 24 months was measured, and the percentage of patients meeting the minimum clinically important difference (MCID) was calculated. Correlations between PROs and SSc‐ILD disease severity measures were also examined.

Results

Treatment with CYC and MMF led to improvements in several PROs with no between‐treatment differences. Scores for the Transitional Dyspnea Index (TDI) and St. George’s Respiratory Questionnaire (SGRQ) improved significantly over 2 years, and 29%/24% and 28%/25% of participants in the CYC/MMF groups met or exceeded the MCID estimates for TDI and SGRQ, respectively. At baseline, the forced vital capacity (FVC) percentage predicted (FVC%‐predicted) did not correlate with the Baseline Dyspnea Index or SGRQ. However, improvements in the FVC%‐predicted were weakly associated with improvements in dyspnea (assessed by the TDI) and SGRQ scores.

Conclusion

Treatment with CYC and MMF improved overall health‐related quality of life in patients with SSc‐ILD. The relationship between PRO measures and the FVC was relatively weak, suggesting that PROs provide complementary information about treatment efficacy not captured by changes in the FVC alone in this patient population.