bluuebunny/crossref_metadata_2025 huggingface dataset:
GEOLOGICAL AND ECONOMIC CRITERIA OF INDUSTRIAL VALUE OF COAL DEPOSITS WITH INSIGNIFICANT RESERVES
Authors: Kurylo M. , Bala V.
Published: April 2019

The purpose of this study is to analyze and systematize criteria by which, in domestic and international practice, the industrial value of coal deposits with small and insignificant reserves is determined. The analysis and systematization of such factors in general for all coal deposits with the definite definition of the most influential characteristics for small stocks are carried out.

Mining and geological factors, which are caused by natural characteristics of the deposit and directly related to the concrete object, are determined, and there have been singled out factors concerning the minerals in general or characterizing the external conditions of industrial development of deposits. For coal deposits with insignificant reserves, the criteria that directly affect the most critical parameter - the value of coal reserves and, consequently, the lifetime of the mining enterprise have paramount importance. Such criteria are the quality of coal, which defines the direction of use and its liquidity, the degree of geological study, which expresses the geological risks of reserves confirmation, and the complexity of mining technical conditions that define methods and systems for the reserves disclosure and development.

In general, external factors for coal deposits are most affected by the availability of raw material substitutes and market conditions, and coal prices. For deposits with insignificant reserves, prices and possibility of mining, which involves availability of licenses and social permits, may have a greater impact.

Industrial significance of deposit with insignificant reserves may appear favorable of all other conditions of development - mining and technical conditions that form low cost of production, coal quality, favorable market conditions for mineral raw materials, localization of the deposit near consumers, etc. At the same time, the main prerequisite for attracting objects with insignificant reserves to exploitation should be their high degree of geological study. Decision about possible industrial significance should be taken after detailed technical and economic calculations.
MR Spektroskopi Temelli Beyin Tümörü Teşhisinde Lojistik Regresyon Uygulaması
Authors: ALTUN Sinan , Alkan Ahmet
Published: April 2019

Beyin tümörü
teşhisinin, birçok hastalık teşhisinde olduğu gibi farklı yöntemler
kullanılarak doğrulanması gerekmektedir. Çünkü yanlış teşhis doğrudan insan
hayatını etkilemektedir. MR Spektroskopi ilk başta laboratuvar çalışmalarında
kullanılmıştır. Daha sonra MR Spektroskopinin su ve yağ haricindeki
metobolitleri ölçebildiği keşfedilmiştir. Bu keşifle beraber,  MR Spektroskopi beyin tümörü teşhisinde doğrulayıcı
bir yöntem olarak kullanılmaya başlanmıştır. MR Spektroskopi ile kolin, kreatin
ve N-Asetil Aspartat metobolit değerleri ölçülür. Bu değerlerin doğru
yorumlanması ciddi bir uzmanlık gerektirir. Yapılacak bir uzman karar destek
sistemi hızlı ve doğru teşhis açısından önemlidir. Çalışma MRS temelli beyin
tümörü teşhisi için yapılabilecek uzman karar destek sisteminin temeli olan
sınıflandırma yöntemlerinin başarımlarının karşılaştırmasını içermektedir.
Lojistik Regresyon yöntemi ve Naive Bayes yöntemi WEKA programında çalışılmıştır.
Naive Bayes’ de % 87 başarım, Lojistik regresyonda % 90 başarım elde
edilmiştir. ROC değerleri ise Naive Bayes için 0,912, Lojistik Regresyon için
0,977 olarak hesaplanmıştır. % 87 sınıflandırma ve 0,912 ROC hesaplaması yüksek
bir başarıdır, ancak Lojistik Regresyon daha iyi sınıflandırma ve ROC alan
hesaplaması yapmıştır. Bu da MRS temelli beyin tümörü teşhisinde uzman karar
destek sistemi oluşturmak için Lojistik Regresyonun, Naive Bayes yöntemine göre
daha uyumlu olabileceğini göstermektedir.
Genesis of marriage law in Spain
Authors: Trofimets I. A.
Published: April 2019

The study of the institution of marriage in the foreign legal order makes it possible not only to see the identity and historical succession, but also to find out whether the provisions on marriage have common features that characterize it as the highest value, and how permissible foreign borrowing in the formation of its own legal system without prejudice to its uniqueness and individuality. The use of foreign experience reveals a lot of issues and conflicts that need to be resolved in relation to national law. An obligatory component is the study of the heritage of the past, the so-called legislative retrospective, which contributes to the knowledge of legal culture. For the first time in domestic science there is an attempt to periodize the institution of marriage in Spain, depending on the type of social regulator: customs, canonical rules, rules of law (own and borrowed). The periodization of the Spanish marriage law is presented and the main features of its formation are shown: the application of the customs of the peoples inhabiting the territory of Spain; the reception of Roman private law; the influence of Canon law; the appearance of foreign influence. The whole history of marriage law is divided into 5 periods: customary law (the first period), the rule of canon law (second period), systematic legislation on marriage (the third period), harmonization of secular marriage legislation with the provisions of canon law (the fourth period), contemporary law (fifth period). Separately, in the settlement of relations between the sexes, a pre-legal period is allocated. Of course, each period is characterized by a variety of rules of marriage law, which is explained by the evolution of social relations and the development of the legal institution of marriage. The consistent influence of universal values on the formation of legal provisions of marriage is shown. As the marriage law is formed, rules are formed that determine the conditions and order of its conclusion. The enduring value of the family organization of the way of life of people and the family form of management determines the preservation of this social institution throughout the period of human history, although in a constantly changing form.
Prosocial legal thought in the age of revolution and civil war in Russia (1917—1918)
Authors: Zaynutdinov D. R.
Published: April 2019

The paper deals with the formation and development of right-socialist legal thought during the revolutionary period of 1917 and the Civil war of 1918. During the analysis, special attention is given to the legal views and ideas of the largest theorists of the right-socialist school, such as G.V. Plekhanov, V.M. Chernov, P.B. Akselrod, M.V. Vishnyak. The paper is divided into four interrelated parts. The first part reveals the fact of the lack prosocial groups of projects of legal development of the Russian state to establish a social democratic regime that caused their appeal to the legal concepts of the cadets. Also the reasons of registration by right-socialist groups of the concept of “the third way” and its realization in anti-Bolshevist statehood of the period of 1918 are revealed. In the second part of the work the understanding of the essence of law in socialism is studied, the comparison of the ideological approach to “law” on the part of the lawyers of the left-socialist and right-socialist camp is made. Special attention is given to the place of law in the teachings of socialism and the relationship of law with the economy. In the third part of the work the image of A.I. Gukovskiy as a jurist of the right socialist camp is investigated. His characteristic given to him by the right Socialists Revolutionarists (SRs) is generalized. The image of A.I. Gukovskiy reveals common features inherent in all legal scholars of the right socialist camp. The fourth part of the paper draws attention to the idea of human and civil rights and freedoms in the teachings of social democracy. For the jurists of social democracy, the development of the idea of human and civil rights and freedoms is nothing more than the materialization of the spirit of the revolution, and therefore the problems of the legal status of the individual in the works of right socialist thinkers received a special place. In conclusion, the author draws conclusions about the contribution of Russian lawyers of the right socialist group to the world fund of legal science.
Discovering new antiretroviral compounds in «Big Data» chemical space of the SAVI library
Authors: Savosina P.I. , Stolbov L.A. , Druzhilovskiy D.S. , Filimonov D.A. , Nicklaus M.C. , Poroikov V.V.
Published: April 2019

Despite significant advances in the application of highly active antiretroviral therapy, the development of new drugs for the treatment of HIV infection remains an important task because the existing drugs do not provide a complete cure, cause serious side effects and lead to the emergence of resistance. In 2015, a consortium of American and European scientists and specialists launched a project to create the SAVI (Synthetically Accessible Virtual Inventory) library. Its 2016 version of over 283 million structures of new easily synthesizable organic molecules, each annotated with a proposed synthetic route, were generated in silico for the purpose of searching for safer and more potent pharmacological substances. We have developed an algorithm for comparing large chemical databases (DB) based on the representation of structural formulas in SMILES codes, and evaluated the possibility of detecting new antiretroviral compounds in the SAVI database. After analyzing the intersection of SAVI with 97 million structures of the PubChem database, we found that only a small part of the SAVI (~0.015%) is represented in PubChem, which indicates a significant novelty of this virtual library. However, among those structures, 632 compounds tested for anti-HIV activity were detected, 41 of which had the desired activity. Thus, our studies for the first time demonstrated that SAVI is a promising source for the search for new anti-HIV compounds.
Podophyllotoxin analogue with bicyclo[3.2.1]octane moiety annelated with indole: synthesis, molecular modeling, and biological testing
Authors: Zefirov N.A. , Lavrushkina E.A. , Kuznetsov S.A. , Zefirova O.N.
Published: April 2019

C4-Ester derivatives of the anticancer agent podophyllotoxin with bridged moieties can either inhibit polymerization of alpha,beta-tubulin with the formation of microtubules (analogously to the parent molecule) or cause an unusual effect of “curling and shortening” of the microtubules (MT). In order to predict the effect of bridged podophyllotoxin derivatives on the MT network using computer molecular modeling it is desirable to enhance the structural diversity of their bridged substituents. In the present work we synthesized novel podophyllotoxin ester with bicyclo[3.2.1]octane moiety annelated with indole core. The target compound was obtained by Steglich esterification of podophyllotoxin by rac-exo-(indolo[2,3-b])bicyclo[3.2.1]oct-2-ene-6-carboxylic acid as diastereomeric (6RS,8SR,9RS) mixture, which could not be separated by thin layer or preparative column chromatography on silica gel. Results of biotesting of 4-O-{(6R,8S,9R)-5,6,7,8,9,10-hexahydro-6,9-methanocyclohepto[b]indol-8-ylcarbonyl}-Lpodophyllotoxin on the carcinoma A549 cells proved its ability to cause full depolymerization of microtubules without curling effect at a concentration 10 μM. Cytotoxicity value of the compound estimated in MTT test was in a high nanomolar concentration interval (EC50=710±30 nM). Computer molecular docking of both isomers of novel compound and earlier synthesized podophyllotoxin esters with bridged moieties into the 3D model of the colchicine domain in alpha,beta-tubulin revealed the difference in positions of the bridge moieties of new compound and MT-curling ligands and allowed to hypothesize that the atypical action on MT might be caused by positioning of their bridge groups near the GTP binding site in alpha-tubulin.
Xenobiotic toxicity prediction combined with xenobiotic metabolism prediction in the human body
Authors: Rudik A.V. , Dmitriev A.V. , Lagunin A.A. , Ivanov S.M. , Filimonov D.A. , Poroikov V.V.
Published: April 2019

The majority of xenobiotics undergo a number of chemical reactions known as biotransformation in human body. The biological activity, toxicity, and other properties of the metabolites may significantly differ from those of the parent compound. Not only xenobiotic itself and its final metabolites produced in large quantities, but the intermediate and final metabolites that are formed in trace quantities, can cause undesirable effects. We have developed a freely available web resource MetaTox (http://www.way2drug.com/mg/) for integral assessment of xenobiotics toxicity taking into account their metabolism in the humans. The generation of the metabolite structures is based on the reaction fragments. The estimates of the probability of the reaction of a certain class and the probability of site of biotransformation are used at the generation of the xenobiotic metabolism pathways. The web resource MetaTox allows researchers to assess the metabolism of compounds in the humans and to obtain assessment of their acute, chronic toxicity, and adverse effects.
Modeling and theoretical analysis of ring specific mimicry in view of isomerism within medicinal promising oligomers of "DIVEMA"
Authors: Bolshchikov B.D. , Tsvetkov V.B. , Alikhanova O.L. , Serbin A.V.
Published: April 2019

The furan or pyran related hetero cycles play basic role in structural units of nucleic acids (NA) and polysaccharides (PS), significantly predetermining their functional specifics. Some of such properties, in great relevancy for medicine, can be imitated through mimicry of polymers synthetic. Particularly, a formation of similar cycloisomeric chains is possible in process of free-radical cyclocopolymerization of divinyl ether (DVE) and maleic anhydride (MA). The products yielded (DVEMA) of general formula [DVE(MA)-alt-MA]n become precursors for a broad family of water-soluble derivatives capable of wide spectrum of bioactivity, including induction of interferon, immune-stimulated and direct antiviral protection. In this connection, the knowledge: what is content of different heterocyclic isomers in backbone of the preparations and what their partial contributions in promotion of the certain bioactivities observed, are in great importance. Available experimental data (NMR, IR, etc.), controversial for interpretations, didn't elucidate a required estimation of the DVEMA isomerism. The current work represents an independent exploration of the problem via quantum chemistry-based analysis of kinetic (activation barriers) and thermodynamic (enthalpies) priorities in competition between variable isomerism within the chain synthesis. The system is considered in maximal range of hypothetically allowable variations of two levels for double regioselective bifurcations: there are four competitive ways, each of which involves a sequence of four type elementary reactions for a diverse-isomeric formation of chain units. A genesis of six chiral centers (62 stereoisomers permitted) per every of the four part ways was accounted in view for up to 256 isomeric variations in total. The required time-minimized but precisely accurate computations were conducted via B3LYP/6-31G(d), M06-2X/6-311+G(d), M06-2X/6-31+G(2df,p) techniques, which were preselected through model test-systems. As a result, the mechanisms, crucial points and factors for the process-permitted regulation of isomeric content of DVEMA were studied in details. The narrow enough set of most probable enantiomers within highly competitive 5-exo- and 6-endo- ring closing sub-ways was revealed. The results obtained are very actual for an adequate modeling (docking / molecular dynamics) of DVEMA derivatives in their interactions with biopolymer targets, in search for purposed advancement of current background in design and synthesis of highly effective agents for combined antiviral protection (against HIV, flu, herpes, and other infections).
Elastography evaluation of normal thyroid gland and its comparison with diffuse non nodular enlarged thyroid gland using strain ultrasound elastography
Authors: Kumar Sanjay , Jain Vishal Kumar , Gupta Ashutosh , Netam Satya Bhuvan Singh , Gupta Nilesh
Published: April 2019

Background: The thyroid gland is located in the anterior part of neck, spanning between C5 and T1 vertebra and is located anterior to the thyroid and cricoids cartilage of larynx and first three tracheal rings. Ultrasonography has been widely used for diagnosis of thyroid disease it is highly regarded for its ease of use, real-time capability, portability and low cost.Methods: The current observational study was conducted in Department of Radiology, Dr. BRAM Hospital, Pt. JNM Medical College, Raipur, India. Consecutive sampling method was used for the study. All the cases coming to radiology department during the study period were taken as study subjects.Results: Of the normal subjects, author found 107 normal thyroid subjects and 53 patients were categorized into cases with diffuse non-nodular thyroid swelling groups. Of the diffuse thyroid swelling group about 85% of the study population is between 20-50 years of age group, 13.2% were <20 years of age and one patient is >50 years of age. Females to male ratio for diffuse thyroid disease is 3.4:1.Conclusions: Ultrasound elastography (USE) is a newly developed non-invasive method to evaluate and compare the elasticity of the thyroid gland and other organs like liver, prostate, parotid, breast pathologies. Its use is based on the principle that pathological changes in a tissue also changes its elasticity.
Severe scoliosis in an adolescent, benefits of early detection: a case report
Authors: Halawani Motssim S.
Published: April 2019

Presentations of scoliosis to primary health care physicians are not rare. Challenges may arise when it comes to screening and who require treatment once diagnosed. Idiopathic scoliosis is a three-dimensional spine and trunk deformity that is considered the most common form of scoliosis in children. It commonly does not cause symptoms and may be overlooked. However, if there was progressive deformity and it remained untreated, it may cause serious complications. Apart from medical concerns, emotional and cosmetic worries due to visible deformity may lead to psychological and social effects. Despite advances in understanding scoliosis, there are still controversies when it comes to optimal screening and treatment of this condition. This case is about a thirteen years old female who presented with intermittent back symptoms and was found to have a severe form of idiopathic thoracolumbar scoliosis. Through this case, author will be discussing different aspects of scoliosis (prevalence, screening, diagnosis, and treatment options) with emphasis on psychological support and guidance to the physician on how to overcome this challenge.
A rare clinical case: schwannoma of tongue
Authors: Singh Chandra Veer , Radia Sheetal , Sheikh Saalim , Haribhakti Vijay
Published: April 2019

Schwannoma are slow growing tumours, which can arise from any peripheral nerve. 10% of schwannomas that occur in the head and neck region mostly originate from the vagus or sympathetic nervous system. Extracranial schwannomas in the head and neck region are rare neoplasm. Intraoral schwannoma are only 1% of the all head and neck tumours. Diagnosis is established by imaging studies such as magnetic resonance imaging or computed tomography, while FNAC is used to rule out other conditions. We report a rare case of lingual schwannomas generally present as a painless lump schwannoma of the tongue in a 27-year-old male complaining of asymptomatic swelling over a posterolateral surface of the tongue, treated by complete surgical excision. The diagnosis was established on the basis of clinical, histopathological, and immunohistochemical examination. We report a rare case of schwannoma over the posterolateral surface of tongue. Prognosis is good for the patient when this condition is correctly diagnosed as the condition rarely recurs after complete resection.
Fluxo de navios e cargas do Porto de Cabedelo (PB)
Authors: Do Nascimento Freitas Maria Eline , Sales Holanda Janaina
Published: April 2019

Cabedelo, a port city, which is part of the Greater João Pessoa Metropolitan Region, is located on a peninsula between the Atlantic Ocean and the river Paraíba. Its port was inaugurated on January 23rd, 1935, after several unsuccessful attempts to build the Port of Capim in João Pessoa, due to the bad conditions of the river in that place. The port is very important for the municipality and for the state, as it is responsible for making Cabedelo the third GDP of the state. For this study, the Companhia Docas da Paraíba provided files with data of vessels that arrived at the port between the years 2010 to 2016. Using these data, electronic spreadsheets were drawn up showing information with the characteristics of the ships (total length, breadth and maximum draught) as well as the main product that disembarked or boarded the port, as import/cabotage or export. The information in this study is important for future studies and investments in port and/or in the port area.
Eficiência dos Gastos Públicos em Educação e a Influência dos Fatores Socioeconômicos para o Estado de Santa Catarina
Authors: Tatiane Salete Mattei Tatiane Salete , Bezerra Fernanda Mendes
Published: April 2019

O objetivo da pesquisa é verificar a influência dos fatores socioeconômicos na eficiência dos municípios de Santa Catarina em alocar os gastos públicos nos primeiros anos da educação fundamental no ano de 2011. Para encontrar o índice de eficiência é utilizada a metodologia não paramétrica Análise Envoltória de Dados (DEA). Para a verificação da influência dos fatores socioeconômicos na eficiência em educação é utilizada a técnica econométrica Regressão Linear Múltipla. Os resultados sugerem que a maioria dos municípios são ineficientes na alocação dos recursos nos primeiros anos da educação básica, visto que apenas uma pequena parcela dos municípios, 21,37%, foram considerados eficientes no ano de 2011. Foi verificado também que os fatores socioeconômicos impactam de forma relevante no desempenho educacional.
Libras para todos: um framework para a criação de Objetos de Aprendizagem.
Authors: Guimarães Cayley , Maestri Rita De Cássia , Fernandes Sueli De Fátima
Published: April 2019

Este artigo discute as dificuldades enfrentadas pelos Surdos na aquisição da língua de sinais, suas consequências emocionais, sociais, psicológicas e de cidadania. Observa a carência de encaminhamentos pedagógicos e educacionais da educação do Surdo, e propõe um framework para a criação de Objetos de Aprendizagem que tenham potencial de aprendizagem significativa. Como prova de conceito, foi construído um Objeto de Aprendizagem - uma casa digital - que apresenta possibilidades de interações voltadas ao desenvolvimento de estruturas pedagógicas. Validações internas da casa concluíram pelo potencial de uso do framework e da casa digital gerada.
Robótica educacional: um recurso para a exploração de conceitos relacionados à transferência de calor
Authors: Da Silva Maurício Veiga , Gonzatti Sônia Elisa Marchi , Böckel Wolmir José
Published: April 2019

Este trabalho aborda a exploração de conceitos relacionados à transferência de calor por meio do kit de robótica LEGO MINDSTORMS® NXT. O trabalho é parte de uma pesquisa de Mestrado Profissional em Ensino de Ciências Exatas. O estudo foi realizado em uma escola da rede privada do município de Vilhena, Rondônia, tendo, como participantes, vinte e dois estudantes do 2° ano do Ensino Médio. O objetivo desta pesquisa foi investigar como o uso de atividades de robótica no ensino médio pode contribuir na exploração de conceitos relacionados à transferência de calor. A pesquisa desenvolvida foi de natureza qualitativa abordando um estudo de caso. Para análise e coleta dos dados, foram feitas observações, aplicação de um questionário prévio e desenvolvimento de atividades pedagógicas com o uso do kit de robótica LEGO MINDSTORMS® NXT e do software LEGO MINDSTORMS® NXT. Os resultados da pesquisa indicaram que as atividades pedagógicas desenvolvidas com os alunos mostraram ser potencialmente relevante, pois contribuíram para a exploração de conceitos físicos relacionados à transferência de calor e proporcionaram aos estudantes uma nova forma de analisar, abordar e compreender conteúdos teóricos no cotidiano.
A experiência de encontro entre sujeitos aprendentes: aspecto da formação docente vivenciado no estágio supervisionado em docência na educação infantil
Authors: Peroza Marilúcia Antônia de Resende , Camargo Daiana
Published: April 2019

Neste artigo pretende-se apresentar, como aspecto fundamental da formação inicial de docentes, as reflexões acerca da experiência de encontro vivenciada por acadêmicos do Curso de Pedagogia com as crianças que frequentam as instituições de Educação Infantil, proporcionada pela disciplina de Estágio Curricular Supervisionado para Docência na Educação Infantil. Fundamentam as reflexões os estudos de Pimenta e Lima (2006) e Rocha e Ostetto (2009), que vêm o estágio como espaço de articulação dos conhecimentos promovidos pelo curso com os saberes que emanam dos sujeitos envolvidos no processo de formação docente e a prática educativa desenvolvida com as crianças. Tomando como base Kuhlmann Jr. (2007), Sarmento (2004), Cerisara (1999), compreende-se a criança enquanto sujeito sócio-histórico-cultural, ativa no processo educativo; e a infância enquanto categoria social que se constitui e reflete as contradições da sociedade mais ampla. A formação docente, conforme Romanowski (2007) e Garcia (1999), exige compromisso, cientificidade, coletividade, competência e comunicabilidade, saberes que são constituídos na relação entre os constructos teóricos e as práticas dos sujeitos, reafirmando uma relação intrínseca entre os aspectos teóricos, práticos e relacionais da formação. Sendo assim, ressalta-se neste estudo, as experiências de encontro vivenciadas por sujeitos em processo de aprendizagem, aqui denominados sujeitos aprendentes. Estas experiências são valorizadas como elementos fundamentais que perpassam a vida cotidiana da escola da infância que, segundo Larrosa (2016), os coloca face a face com o desconhecido, abrindo possibilidades para novos conhecimentos. Ressalta-se que o estágio na Educação Infantil precisa ser valorizado como um espaço privilegiado para constituir um novo olhar sobre a criança e sobre a formação de professores, no sentido de se tornarem sensíveis às crianças em suas necessidades e possibilidades. Por fim, destaca-se a dimensão da experiência de encontro com a criança como sendo um elemento significativo da formação docente para atuar na Educação Infantil.
A promoção da educação literária na disciplina de Inglês no 1.º Ciclo do Ensino Básico
Authors: Balça Angela
Published: April 2019

O estudo apresentado decorreu da introdução, no sistema educativo português, da disciplina de Inglês no 1.º Ciclo do Ensino Básico, com um carácter obrigatório. Os documentos oficiais, que regem esta disciplina, ignoram a vertente da educação literária e não privilegiam o trabalho em sala de aula com obras de literatura infantil em língua inglesa. Deste modo, com este estudo, apostou-se na promoção da educação literária na aula de língua inglesa, com alunos deste ciclo de ensino. Este estudo tinha como objetivos proporcionar aos alunos o contacto e a leitura do livro de literatura infantil em língua inglesa; contribuir para o desenvolvimento da competência linguística e da competência literária dos alunos em língua inglesa; contribuir para a promoção da educação literária dos alunos, através do livro de literatura infantil em língua inglesa. Metodologicamente, este estudo centra-se na linha de investigação/ação/reflexão sobre a própria prática docente. O trabalho de campo desenvolveu-se através de um projeto de leitura com o livro de literatura infantil em língua inglesa. Como instrumentos de recolha de dados, utilizou-se a observação participante, as notas de campo, os registos áudio e fotográficos e as próprias produções escritas e plásticas dos alunos. Os resultados demonstraram que os alunos aprenderam vocabulário e treinaram construções gramaticais; conheceram textos, autores e ilustradores; tomaram contacto com a realidade da vivência inglesa; desenvolveram a competência linguística e a competência literária.
ENVIRONMENTAL PROBLEMS OF TREATMENT OF SALINE LANDS FOR AGRICULTURAL NEEDS IN THE FIRST AGRO-CLIMATIC ZONE OF THE STAVROPOL TERRITORY
Authors: Loshakov A. V. , Klyushin P. V. , Shirokova V. A. , Khutorova A. O. , Savinova S. V.
Published: April 2019

Aim. The aim of the study is to assess the environmental problems and develop a proposal for the identification and analysis of the state of saline and solonetzic lands. Basing on this research, it is crucial to develop proposals for the effective use of lands for the agricultural needs in the first agro-climatic zone of the Stavropol Territory.

Methods. Monitoring studies of agricultural lands were carried out using modern methods which include both remote sensing and annual local surveys in areas of the first agro-climatic zone of the Stavropol Territory. Based on this, agricultural land was divided into four groups: highly productive, productive, low productive and unproductive.

Results. It has been established that the territory of the first agro-climatic zone is represented by agricultural lands for more than 95%, and over the 16-year study period, the area of these lands increased by 27,906 ha. Salinization of land is global in nature, since the total area of land with a degree of salinity is 644,334 ha, that is, more than 37% of agricultural land in this agroclimatic zone is already salinized to varying degrees. In addition, solonetzic complexes are widespread here.

Conclusion. We have established that in order to increase the efficiency of the use of these lands, their qualitative zoning with the subsequent development of agromeliorative measures is necessary. This division of land reflects their qualitative condition, degree of exposure to various degradation processes, the possibility of further land use, a set of measures for the preservation, restoration and protection of these lands and securing the corresponding status of a particular zone based on the developed regulations.
FORECASTING VALUES OF CHROMATICITY OF DRINKING AND SOURCE WATERS USING ARIMA MODEL AND NEURAL NETWORK
Authors: Makarov D. V. , Kantor E. A. , Krasulina N. A. , Greb A. V. , Berezhnova Z. Z.
Published: April 2019

Aim. In the present investigation artificial neural network (ANN) and ARIMA-model are compared for forecasting of data of colour of water.

Methods. Data corresponds to the colour of water of groundwater and drinking water of water intake of south-east region of the Republic of Belarus. The definition of colour was carried out for the period from 2009 to 2017. twice a day, the time series of values included 5215 values. The parameters of the models were estimated by 85% of the time series values, and the remaining 15% of the values (the test period) compared the forecast values with the actual ones. Optimal configurations of ARIMA-models were determined from the results of comparing the averaged values of the root mean squared errors (RMSE); optimal configurations of ANN were determined from the results of comparing the averaged values of RMSE and correlation coefficients (CC) on the test periods.

Results. Comparison of forecasting methods was carried out on the basis of the averaged values of mean absolute error and mean relative error on the test periods. It was revealed that ANN allows to obtain the predicted values of colour of water more accurate than ARIMA-model.

Main conclusions. Software implementation of ANN in the MATLAB environment empowers with sufficient accuracy get forecast values of groundwater and drinking water for 100 values.
SPECIES COMPOSITION OF COMMERCIAL FISH CATCHES IN WATER BODIES OF THE STAVROPOL TERRITORY FOR THE PERIOD OF THE LATE XX – EARLY XXI CENTURIES
Authors: Mishvelov E. G. , Bakumenko I. A.
Published: April 2019

Aim. The aim of the study is to analyze the species composition of commercial fish catches in water bodies of the Stavropol Territory for two periods from 1986 to the present.

Methods. The first period from 1986 to 2003 is conventionally highlighted and the second period from 2009 to 2017. Data on linear and area characteristics of the territorial objects was obtained using Landsat 8 satellite imagery.

Results. In 2017, in the fish industry of the Stavropol Territory, 10.8 thousand tons of marketable fish were produced, which was about 70% of the best production level in 1990. The share of common carp production was 58%, silver carp – 34%, white Amur – 5% , other carp fish species – 3%, trout and sturgeon – 1%. In 2017, 1415 tons of fish seeds were produced bringing the total to 19 million units, which is 4 times less than in 1990. The importance of fish catching in providing the population of the region with fish is not so great in comparison with fish farming. In different periods of the last thirty years, the total annual catch in regional state water bodies (reservoirs) ranged from a maximum of 1065 tons (1990) to a minimum of 82 tons (2016). The average annual catch in all state water bodies for the period 1986 – 2003 amounted to 357 tons; fish productivity was 32 kg, with fluctuations from 2 to 113 kg/ha in eleven water bodies. Over the past 9 years, since 2009, the average annual catch in all state water bodies has decreased and amounted to 285 tons.

Conclusion. For the period of 1986-2003, the average annual catch of common carp and silver crucian carp was 94 tons each and 79 tons of silver carp; the total share of these three species in catches was 85%. Over the past 9 years (2009-2017), the total share of these fish in the catches has decreased to 66%. The average annual catch of common carp and silver carps was almost halved, while the catch of less valuable silver crucian carp increased and reached 103 tons.
ANALYSIS OF DYNAMICS AND SOURCES OF MANGANESE, COPPER, NICKEL AND ALUMINUM IONS FOUND IN THE TRANS-BORDER MIUS RIVER DURING THE PERIOD FROM 2003 TO 2017
Authors: Vorobyov E. V. , Usova E. V. , Orekhova Yu. V.
Published: April 2019

Aim. Transboundary rivers are complex enough to study which requires analysis of not only the polluting agents themselves but also geographic features and specifics of economic activities. The work is devoted to the study of the dynamics of pollution of the Mius River with ions of manganese, copper, nickel and aluminum, taking into account the peculiarities of the regions through which the river flows and the specifics of the anthropogenic load on the adjacent territories.

Material and methods. The article considers some natural and anthropogenic factors that determine the increased content of metal ions in the transboundary river Mius, taking into account the peculiarities of the territory of the river. Based on the monitoring data from 2003 to 2017, the dynamics of river pollution by aluminum, manganese, copper and nickel were presented; monthly averages for the period under review were also given.

Results. It is revealed that pollution has an annual periodicity which depends on natural factors and metallurgical industry, characteristic of Donbass. The negative effect of these metals on human health and environment was indicated.

Conclusion. There is a connection between changes in concentrations of the metals of concern, which indicates the predominance of the anthropogenic source of metals over natural in the Mius River.
İllerin Sağlık Endeksi: Bileşik Endeks Yaklaşımı ile Bir Deneme
Authors: ÇAĞLAR Atalay , KETEN Nur Duygu
Published: April 2019

Amaç: Bu çalışmanın amacı Türkiye’deki 81 ilin sağlık göstergelerine göre göreceli olarak karşılaştırılmasına olanak sağlayacak bir endeks geliştirmektir.Gereç ve Yöntemler: Önce, Altyapı, İnsan Kaynağı, Hizmet ve Sağlık Göstergesi olmak üzere dört alt endeks oluşturulmuştur. Daha sonra dört alt endeksin aritmetik ortalaması alınarak Sağlık Endeksi bulunmuştur. Alt endekslerin bulunmasında illeri göreceli olarak değerlendiren doğrusal programlama tabanlı bir model kullanılmıştır.Bulgular: İlk ve son sırada yer alan iller; Altyapı Endeksi’nde Burdur ve Hakkari, İnsan Kaynağı Endeksi’nde Kırıkkale ve Şırnak, Hizmet Endeksi’nde Aydın ve Şırnak, Sağlık Göstergesi Endeksi’nde Muğla ve Kilis’tir. Sağlık Endeksi’nde ilk beş sıradaki iller Trabzon, Malatya, Burdur, Denizli, Bolu iken son beş sıradaki iller Van, Muş, Ağrı, Hakkari, Şırnak olarak bulunmuştur. İlk on sıradaki illerin 3 tanesi Ege (Denizli, Muğla, Uşak), 2’şer tanesi Akdeniz (Burdur, Isparta) ve Doğu Karadeniz (Trabzon, Rize), 1’er tanesi Ortadoğu Anadolu (Malatya), Doğu Marmara (Bolu) ve Kuzeydoğu Anadolu (Erzurum) ilidir. Son on ilin bölgesel dağılımı incelendiğinde, 4 tanesi Ortadoğu Anadolu (Bingöl, Van, Muş, Hakkari), 2’şer tanesi Kuzeydoğu Anadolu (Kars, Ağrı) ve Güneydoğu Anadolu (Şanlıurfa, Şırnak), 1’er tanesi Doğu Marmara (Bilecik) ve Batı Karadeniz (Kastamonu) Bölgesi’ndendir.Sonuç: Bu çalışmada illerin sağlık göstergelerine ilişkin alt boyutları değerlendiren alt endeksler ve bu boyutların bileşiminden oluşan genel bir değerlendirme sağlayan Sağlık Endeksi hesaplanmıştır. Her bir gösterge için oluşturulan sıralamalar incelendiğinde, Doğu ve Güneydoğu bölgesinde yer alan illerin birkaç istisna dışında son sıralarda bulunması dikkat çekmektedir.
Kreatywność antropologiczna
Authors: Kopciuch Leszek
Published: April 2019

Przedmiotem artykułu jest ogólna relacja między różnymi modelami ludzkiej natury a możliwymi różnymi sensami kreatywności. Gówna teza stwierdza, że ze względu na różne możliwe znaczenia nowości oraz związanej z nią kreatywności nie istnieje taki model, który by wykluczał możliwość zachowań kreatywnych. Jednakże najbardziej skrajny sens kreatywności zawierają tylko te modele, które negują materialną naturę człowieka określonej materialnie. W celu uzasadnienia takiego ujęcia odwołuję się szczególnie do koncepcji J. Ortegi oraz J.-P. Sartre’a.
Twórczy potencjał Internetu w zakresie upowszechniania kultury. Blogi o muzyce poważnej
Authors: Sasin Magdalena
Published: April 2019

W niniejszym artykule Internet przedstawiony jest z punktu widzenia potencjału pobudzania kreatywności w zakresie upowszechniania sztuki. Z licznych przejawów upowszechniania sztuki w Internecie do analizy wybrano blogi na temat muzyki poważnej. Artykuł składa się z dwóch części: w pierwszej z nich autorka podejmuje próbę zdefiniowania twórczego potencjału Internetu w zakresie upowszechniania kultury przez pryzmat konkretnych czynników. Korzysta przy tym z istniejących teorii klimatu twórczego oraz środowiskowych stymulatorów i inhibitorów twórczości. W drugiej części artykułu wyróżnione czynniki znajdują zastosowanie w badaniu wybranych blogów o muzyce poważnej. Badania pozwalają zauważyć szereg różnic w stosunku do tradycyjnych form upowszechniania sztuki, a także prowadzą do wniosku, że blogi są formą tzw. twórczości codziennej, stymulowanej twórczym potencjałem Internetu.
¿De qué arte hablamos cuando hablamos de arte en educación?
Authors: Herrera Beltrán Claudia Ximena
Published: April 2019

This paper aims to delve deeper into how art is understood and, consequently, the changes that are made to it in order to introduce it in schools. A series of theses and monographs resulting from research conducted in different universities, particularly as part of the training of students from Bachelor of Arts, Master of Arts and specialization programs, were analyzed. Thus, art education, as knowledge, appears to renounce the knowledge of art: theories, techniques, instruments, the work. All of this occurs under the premise of the wishes of the student, who is not interested in the rules, the limits and, much less, the theory of art and the technique
Kızılcık (Cornus mas L.) Genotiplerinin Yeşil Çelik İle Çoğaltılması Üzerine Araştırmalar
Authors: BALTA Mehmet Fikret , EROL İbrahim Ulvi , ÖZRENK Koray , KARAKAYA Orhan , UZUN Serkan
Published: April 2019

Bu çalışma, farklı kızılcık (Cornus
mas L.) genotiplerinin yeşil çelik ile çoğaltma olanağının belirlenmesi
amacı ile yürütülmüştür. Araştırmanın bitkisel materyalini; ‘44-18’, ‘Güney
uzun’, ‘Güney yuvarlak’, ‘Mehmet’ ve ‘Turgut’ genotipleri ile Yalçınkaya-77 standart
kızılcık çeşidi oluşturmuştur. Çalışmada yeşil çelikler, incelenen bitkilerden
15 Haziran 2014 tarihinde alınmıştır. Hazırlanan çelikler iki gruba ayrılarak
yarısına 3500 ppm indol-3 bütirik asit (IBA) uygulaması yapılmış, diğer
yarısına ise herhangi bir uygulama yapılmamıştır (kontrol grubu). Dikimden 5
hafta sonra sökülen kızılcık çeliklerinde köklenme oranı, kalluslenme oranı, en
uzun kök, en kısa kök, kök dallanması, yaşayan çelik oranı ve köklenme kalitesi
özellikleri incelenmiştir. Çalışmada kontrol grubu çeliklerde incelenen
özellikler bakımından kayda değer bir sonuç elde edilememiştir. Araştırma
sonucuna göre, IBA uygulanan (3500 ppm) kızılcık yeşil çeliklerinde; köklenme
oranı % 80 ile         % 100, kök sayısı
12.86 adet çelik-1 ile 42.94 adet çelik-1, kalluslenme
oranı % 13.30 ile % 73.30, en uzun kök boyu 7.74 mm ile 23.88 mm, en kısa kök
boyu 1.39 mm ile 3.77 mm, köklenme kalitesi 1.56 puan ile 2.93 puan arasında
belirlenmiştir. Sonuç olarak, fidan kalitesi üzerine etkili olan köklenme
oranı, kök sayısı ve köklenme kalitesi özellikleri “Mehmet” genotipinde diğer
genotiplere göre daha yüksek bulunmuştur. Bu genotipin kızılcık meyve türünde
yapılacak ıslah ve çeşit geliştirme çalışmalarında kullanılması önerilmektedir.
Por um novo modelo de professor: os livros publicados pela Cades
Authors: Miranda Bruna Camila Both , Garnica Antonio Vicente Marafioti
Published: April 2019

O presente artigo, inscrito no campo da História da Educação Matemática, apresenta um estudo sobre as obras publicadas pela Campanha de Aperfeiçoamento e Difusão do Ensino Secundário (Cades), de modo especial aquelas voltadas ao ensino de Matemática. Defendemos que tais obras – junto a outras ações implementadas pela Campanha – foram uma tática da Cades para criar um novo modelo de professor secundário no Brasil, nas décadas de 1950 e 1960, quando tanto o mercado quanto o contexto político e social exigiam alterações fundamentais na escola e nas práticas pedagógicas de seus professores.
The Role of Retro Brand Experience in Repurchase Intention and Brand Loyalty
Authors: Pinarbasi Fatih , Türkyılmaz Ceyda Aysuna
Published: April 2019

Concepts such as retro marketing, retro branding and nostalgia marketing are important issues that have come to the agenda in recent years in our world, which is undergoing intensive change and transformation processes. The longing for past periods can be an important source of marketing work for the consumer. Few scientific studies have been conducted in Turkey for retro marketing. It is possible to carry out researches on retro marketing and retro branding, to test relations with different concepts and to develop the researches in detailed form. The aim of this study is to determine whether the general hypotheses tested in the literature will have the same effect on brands carrying retro marketing activities. The scales for the concepts in the research were taken from the literature and 401 participants were reached by convenience sampling method. As a result of the study, it was detected that the dimensions of retro brand experience affect the intention of re-purchasing and brand loyalty. It has also been observed that the retro brand experience dimensions also affect the retro brand attitude, retro brand credibility and customer satisfaction. Finally, it has been tested whether retro brand attitude, retro brand credibility, and customer satisfaction concepts affect repurchase intention and brand loyalty. As a result, it has been observed that these concepts affect repurchase intention and brand loyalty.
Genetics in familial hypercholesterolaemia – from genetic research to new guidelines
Authors: Prokop Edyta Kinga , Jagodziński Paweł Piotr , Grajek Stefan
Published: April 2019

Familial Hypercholesterolaemia (FH) is genetic disorder touching up to 1 to 250 people, increasing the risk of atherosclerotic cardiovascular disease risk and early death by 3–13 times. The majority of mutations are autosomal dominant among 3 genes related to cholesterole metabolism: LDL‑receptor (LDLR), apolipoprotein B (APOB) or proprotein convertase subtilisin/kexin type 9 (PCSK9). It comprises 60% of reported cases, which still is not at satisfactory level. This article summarizes new research in the field of FH and points out new therapeutic methods — PCSK9 inhibitors as advised in new European Society of Cardiology guidelines od dyslipidaemias.
The influence of the shift work system on dietary factors contributing to the development of cardiovascular diseases
Authors: Dobrzyńska Małgorzata Anna , Górna Ilona , Kosewski Grzegorz , Kowalówka Magdalena , Bolesławska Izabela , Morawska Anna , Przysławski Juliusz
Published: April 2019

Aim. The aim of this study was to assess eating behavior in the groups of women who are working on different, unchanged shifts as well as identifying differences in the consumption of nutrients that may increase the risk of cardiovascular disease.Material and Methods. The study was carried out among 300 randomly selected women working in a permanent shift (morning, afternoon, night). In the study, the assessment of the daily intake was carried out using 24-h dietary recall. Anthropometric measurements were carried out to assess the nutritional status. The interview regarding the food consumption was complemented by dietary questionnaire about selected lifestyle parameters contributing to the development of cardiovascular disease and the type of their work.Results. The body mass index (BMI) in all groups was within the adequate values. The analysis of waist to hip ratio (WHR) showed that in the morning and night shift, was exceeded the adequate values recommended in the prevention of cardiovascular disease (WHR = 0.83 ± 0.1 in both groups). The analysis of the daily food rations of women revealed disparities regarding nutritional recommendations. Statistically significant differences in protein and saccharose intake were observed (p > 0.05). The average vitamin D content in the daily food rations of women was insufficient (average 1.4 µg per day); however, it was not statistically significant.Conclusions. The shift work system was influence on eating behaviors in study women. In particular in women which were worked on the night shift, which may contribute to the development of cardiovascular disease in the future.
Peculiarities of the Epidemic Situation on West Nile Fever in the Territory of the Russian Federation in 2018 and Forecast of its Development in 2019
Authors: Alekseychik I. O. , Putintseva E. V. , Smelyansky V. P. , Boroday N. V. , Alieva A. K. , Agarkova E. A. , Chesnokova S. N. , Fomina V. K. , Baturin A. K. , Zhukov K. V. , Shakhov L. O. , Pakskina N. D. , Demina Yu. V. , Ezhlova E. V. , Viktorov D. V. , Toporkov A. V.
Published: April 2019

The epidemic rise in the incidence of West Nile fever (WNF) in the season of 2018 was observed in the countries of the European Union (EU) and bordering states and exceeded the values of all previously recorded epidemic rises of 2010–2012. An increase in the incidence rate was registered in the USA and Canada, however, it did not exceed the indicators of epidemic rises of 2007–2012. In the territory of the Russian Federation, the WNF epidemiological process became more intense mainly in the territory of the Southern and North Caucasian Federal Districts. In general, in Russia, the incidence rates were 2 times lower than the average annual rates, but significantly exceeded those of 2017. The epidemic process had a number of peculiarities in the seasonality, the structure of morbidity and the clinical manifestation of WNF. Genotyping of the isolated WNV RNA fragments from clinical and biological material showed that I, II and IV West Nile virus genotypes were circulating in the European part of Russia. Forecast of epidemic situation development in 2019 reveals further increase in the incidence and does not exclude the possibility of a significant localincrease of WNF incidence in certain regions of Russia.