bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostic Accuracy of Primary Care Clinicians Across a Statewide System of Autism Evaluation
Authors: McNally Keehn Rebecca , Swigonski Nancy , Enneking Brett , Ryan Tybytha , Monahan Patrick , Martin Ann Marie , Hamrick Lisa , Kadlaskar Girija , Paxton Angela , Ciccarelli Mary , Keehn Brandon
Published: July 2023

OBJECTIVES

To evaluate the diagnostic accuracy of the Early Autism Evaluation (EAE) Hub system, a statewide network that provides specialized training and collaborative support to community primary care providers in the diagnosis of young children at risk for autism spectrum disorder (ASD).

METHODS

EAE Hub clinicians referred children, aged 14 to 48 months, to this prospective diagnostic study for blinded follow-up expert evaluation including assessment of developmental level, adaptive behavior, and ASD symptom severity. The primary outcome was agreement on categorical ASD diagnosis between EAE Hub clinician (index diagnosis) and ASD expert (reference standard).

RESULTS

Among 126 children (mean age: 2.6 years; 77% male; 14% Latinx; 66% non-Latinx white), 82% (n = 103) had consistent ASD outcomes between the index and reference evaluation. Sensitivity was 81.5%, specificity was 82.4%, positive predictive value was 92.6%, and negative predictive value was 62.2%. There was no difference in accuracy by EAE Hub clinician or site. Across measures of development, there were significant differences between true positive and false negative (FN) cases (all Ps < .001; Cohen’s d = 1.1–1.4), with true positive cases evidencing greater impairment.

CONCLUSIONS

Community-based primary care clinicians who receive specialty training can make accurate ASD diagnoses in most cases. Diagnostic disagreements were predominately FN cases in which EAE Hub clinicians had difficulty differentiating ASD and global developmental delay. FN cases were associated with a differential diagnostic and phenotypic profile. This research has significant implications for the development of future population health solutions that address ASD diagnostic delays.
Laboratorio de psicofisiología para la evaluación, intervención e investigación de procesos psicológicos
Authors:   Universidad Cooperativa de Colombia, Parada Durán Silvia Inés
Published: July 2023

La práctica de laboratorio de psicofisiología es una actividad complementaria a la conceptualización teórica desarrollada en el aula, incorporando recursos didácticos para el desarrollo de competencias generales y específicas para un proceso académico significativo, el cual permite a los estudiantes participar activamente en la construcción de su propio conocimiento, en un contexto experiencial, de descubrimiento e investigación. Los ambientes prácticos de aprendizaje (APA) motivan al estudiante a la investigación científica y potencian habilidades de observación, identificación, comparación, análisis y discusión. En esta guía, se incluyen contenidos teóricos que facilitan al estudiante la preparación del conocimiento para el desarrollo práctico en el laboratorio. Adicionalmente, esta guía dispone de actividades dinámicas de estudio en grupos de trabajo para mejorar su comprensión. Incluye parámetros claves para la presentación del informe del desarrollo de la actividad práctica. Esta guía práctica corresponde a uno de los componentes desarrollados en el curso de Neurociencia Cognitiva y del Comportamiento para los estudiantes de segundo semestre de Psicología.
James Laughlin, American Modernism and Post World War II Welsh Writing in English
Authors: Lloyd David
Published: July 2023

James Laughlin, who founded New Directions Press in 1936, had an early and enduring commitment to publishing innovative European authors, including Jorge Luis Borges, Louis Ferdinand Céline, Hermann Hesse, García Lorca, Eugenio Montale, Vladimir Nabokov and Pablo Neruda. Laughlin’s international ambitions as a publisher extended to engaging with contemporary British writers and journal editors demonstrating a modernist dimension, evidenced in his extensive correspondence. This essay explores ways in which Laughlin furthered the New Direction Press publishing objectives within the post World War II English-language literary culture of Wales, including his interactions with Dylan Thomas, editors Keidrych Rhys and Gwyn Jones, and significant poets and fiction writers emerging in Wales during the 1940s. While Laughlin was informing Welsh writers and editors about New Directions Press authors and titles – and thus about manifestations of international modernism – Welsh writers and editors in turn educated Laughlin about the burgeoning English-language literary culture of Wales. 
iPhone LiDAR tutorial v2
Authors: Luetzenburg Gregor
Published: July 2023

Recording, exporting and analyzing iPhone LiDAR data The aim of this tutorial is to provide a guide on how to create models of the earth surface on a small to medium scale with the LiDAR sensor built in the Apple iPhones, edit and export those models to a computer, and measure differences between models. This protocol requires an Apple iPhone with a built in LiDAR scanner and the free ‘3d Scanner App’ from the Apple App Store, as well as a computer with the freely available CloudCompare software installed. Optionally, a selfie stick can be used to increase the extent of the scanning area. For data transfer from the iPhone to a non-apple device (e.g. windows pc) login credentials to a cloud service (e.g. Dropbox, Google Drive, OneDrive, iCloud) are required.
Emergent Cultural Contradictions from Overlapping Cultural Levels in Information Systems Development
Authors:   Department of Information Systems, University of Cape Town, Geeling Sharon , Brown Irwin ,   Department of Information Systems, University of Cape Town, Weimann Peter ,   Department of Information Systems, University of Cape Town
Published: July 2023

Research exploring the cultural influence on information system development (ISD) projects tends to focus on a single level of influence (e.g., organizational culture) or cultural incompatibility between one or two cultural levels that are assumed to be discretely separate and static (e.g., national and organizational culture). In contrast, our research conceptualizes culture as dynamic and emergent, with varying levels of overlapping cultures that occur simultaneously in ISD projects (e.g., organizational and occupational culture overlaps). The case study method is used to examine two strategic projects in a single organization in South Africa. The findings describe how the overlap of different cultural levels gives rise to cultural contradictions in ISD projects. Understanding the relevance of the multiple cultures that exist in ISD projects offers further opportunity for refining explanations of cultural contradictions. Cultural contradictions that emerge from cultural overlaps during ISD are conceptualized as five distinct types: Vision Contradictions, Priority Contradictions, Process Contradictions, Role Contradictions, and Technology Contradictions. Despite variation in the context of each project, there is a similarity in the nature and effect of emergent cultural contradictions. The paper concludes with suggestions for addressing cultural contradictions in and influences on ISD projects.
Evaluation of Consistency of Evidence in the Sentencing and its Review in Higher Courts
Authors: Astafyev Aleksey Y.
Published: July 2023

This article touches upon the issues of assessing the reliability of evidence in the verdict in the case of contradictions in the facts examined in the court. The procedure for eliminating contradictions in evidence, as noted in the work, is directly related to the substantiation of the courts conclusions in the verdict. The author addresses the problem of comparability of evidence in a criminal case and points out that in criminal proceedings there are situations of inconsistency of information in which individual contradictions in the evidence examined do not entail their mutual exclusion. It is noted that the work with contradictions in the evidence shows the true ability of the law enforcer to analytical thinking. Based on the analysis of judicial practice, a number of logical and legal methods for substantiating conclusions can be distinguished, which courts resort to when assessing the reliability of evidence and eliminating contradictions between them.
Viruela símica en un paciente con VIH: reporte de caso
Authors: Franco Lacato Alex Omar , Chaparro Mérida Nataniel Aldo , Moreno Samper Dayany , Orellana Padilla Delmira Selmira , Vides Melendres Daniel , Auza Santivañez Jhossmar Cristians
Published: July 2023

La viruela símica es una enfermedad zoonótica endémica en algunas zonas de África; desde mayo  del 2022 se confirmaron múltiples reportes de viruela símica (VS) en países no endémicos. Se presenta el caso de un paciente con antecedente de VIH con exantemas en diversas regiones del cuerpo, con mayor concentración en la región glútea, asociado a adenopatías cervicales y proctitis infecciosa. Se procedió a la toma de la muestra de las lesiones dermatológicas para el estudio molecular de reacción en cadena de la polimerasa en tiempo real (RT-PCR), que confirmó el diagnóstico de VS. La infección por Treponemapallidum y Neisseria gonorrhoeae se identificó mediante serología y cultivo de secreción anal, respectivamente. Se aplicó tratamiento con antibióticos específicos para gonorrea y sífilis, y la VS respondió favorablemente a la terapia sintomática e inmunomoduladora.
About theory of hybride TWTO and an amplifire with a complex permittivity
Authors:   Saratov State University, Funtov Aleksandr
Published: July 2023

The purpose of this work is to construct a nonlinear theory of a hybrid between travelling wave tube (TWT) and an amplifier with a complex permittivity. Methods. The following model is considered: an ion-compensated one-dimensional electron beam penetrates the input travelling wave tube section, then flies into a medium with a complex permittivity, and then enters the output travelling wave tube section. A linear theory of this hybrid is constructed, and its results are compared with the results of the well-known linear theory of travelling wave tube. A nonlinear theory of this hybrid was constructed by a modified wave method, and the results were compared with the nonlinear travelling wave tube theory obtained by the classical Ovcharov–Solntsev’s wave method. In addition, to test the limits of applicability of the obtained results, a stationary nonlinear theory of the hybrid was constructed, obtained using the large particle method. The results of this theory were also compared with the stationary nonlinear travelling wave tube theory constructed using the large particle method. Results and conclusion. Based on the results of the developed theories, it is shown that, under certain parameters, the linear theory and nonlinear theories (both by the modified Ovcharov–Solntsev’s wave method and by the large particle method) make it possible to obtain comparable results both in the case of a classical travelling wave tube and for the hybrid under study. It is shown that under certain parameters, due to the resistive instability, the bunching of electrons can be noticeably improved and, as a result, the gain of the hybrid can exceed the gain in a classical travelling wave tube with the same parameters and the same total length of the device in the linear mode of operation. In the nonlinear mode of operation, the specified hybrid, with optimal environmental parameters, can have significantly higher values of output power and efficiency than travelling wave tube with the same value of the space charge parameter and the Pierce parameter.
Role of Leader in Improving Institutional Climate
Authors: Shahi Dr. Raj Sharan
Published: July 2023

Koontz and Weihrich (1988, p. 437) have defined Leadership “as influence, the art or process ofinfluencing people so that they will strive willingly and enthusiastically towards achievement of groupgoals. Ideally people should be encouraged to develop not only willingness to work with zeal andconfidence. Zeal is order, earnestness and intensity in the execution of work; confidence reflectsexperience and technical ability. Leaders act to help a group attain objectives through the maximumapplication of its capabilities. They do not stand behind a group to push and prod ; they place themsalve before the group as they facilitate progress and inspire the group to accomplish organizationalgoals. Hence Leadership is the quality to lead others to accomplish the set goals of organization andwho occupies this quality, is a leader.
Information and Communication Technology (ICT) and International Terrorism: Boko Haram and Al Shabaab in Perspective
Authors: Uwak Dr. , Egemuka U. Eyo, , Collins C.
Published: July 2023

This study examined the relationship between Information and Communication Technology (ICT) and international terrorism with regards to the activities of terrorist groups. This was premised on the fact that ICT has created a network with a truly global reach for advancement of terrorist activities. The internet technology makes it easy for an individual to communicate with relative ease and anonymity, quickly and effectively across borders to an almost limitless audience. This factor made ICT and their innovative tendencies of the social media like Whatsapp, Facebook, Instagram, Youtube, Twitter etc to serve as veritable tool and motivation for terrorist groups and their activities. Historical and descriptive methods were employed in this study hence data were drawn from relevant primary and secondary sources which included published and unpublished materials. The findings of the study revealed that increased availability of ICT and other innovative tendencies has made it easier for terrorist organizations to communicate, recruit, radicalize as well as mobilize individuals to plan and coordinate terrorist attacks. Based on the above findings, it was recommended among others that understanding terrorist recruitment through the social media was vital to counter-terrorism. Hence, understanding how and why an individual is radicalize and recruited into a terrorist organization is therefore an important part of addressing the fight against terrorism. Accordingly, there should be investment in scientific research and industrial development that are more resistant for terrorist use.
Design and laying out of roads and paths in Greece for better management and development of the forest area
Authors: Liampas Sarantis-Angelos , DROSOS VASILEIOS
Published: July 2023

The forest covers everyday many human needs (e.g. recreation, walking, hiking, mountaineering, training, sports, etc.). These activities are achieved through the use of paths, which are now well developed and have taken the form of a network. During the past they constituted shaped ways by pedestrians and animals in order to join places that have for man any particular interest.

Today, with technology development, in their mapping and surveying was given to them great importance, because they serve as mentioned above many activities and at the same time constitute an ecological form of road, friendlier to the environment than other classic routes.

In consequence, depending on the regions we want to approach, potential users, the length, the degree of difficulty and their shape, we distinguish the paths in various categories (paths of big corridors, mountaineering paths hiking trails, peripatetic paths, educational paths and in combinations of paths). Greece except from the national trails contains also parts of two international paths (E4, E6).

The design and laying out of paths is judged essential because it constitutes important tool of sustainable management. In order to laying out of the paths and the production of maps can be used several devices and instruments such as the Global Positioning System (GPS) and the electronic compass - finder (TruePulse 360° B).

These devices provide us with enough information about the terrain and they contribute to the creation of topographical activities in order to develop the area as it appears in this paper. The study area is a typical semi mountainous area in the Macedonia region.

The results of the measurements are presented in GIS, where the final shape of the path is appeared, and the points of measurement are given in tables. The mapping can be extended and the results of the surveying can be included in a printed or electronic map data in order to be used by stakeholders.
Relationship Factors Between Supply Chain Actors
Authors: Kozma Tímea , Faragóné Lepp Katalin , Szabó-Geletóczki Rita
Published: July 2023

The competition between companies is now in fact competition between value chains and supply chains. Nowadays, companies that participate in an efficiently managed supply chain based on partnerships are leading the increasingly competitive market. The companies must have recognising that the development of close strategic relationships and network cooperation between chain members is an essential part of market competition. The problem is that few company realise this yet. In the framework of the Budapest Business School Supply Chain and Value Chain Research Group, we are trying to explore the supply chain and logistics practices of Hungarian companies and institutions. Our research aims to identify the most important factors for successful business relationships. Our results show that long-term strategie business connections lead to success. Based on our research, we can say, a business point of view, trust, communication and cooperation become competitive factors.
Public and Private Financing Instruments to Support SDGs: The Case of Albania
Authors: Gjaci Blerina
Published: July 2023

The purpose of this paper is to identify and promote actions to finance the SDGs by bringing together governments, the private sector and the civil society. Following the rule ‘it takes money to make money’, the tight fiscal space of Albania is analysed to present potential approaches that can boost private financing leverage. Private finance is the main contributor to support the SDGs, while public finance has a small financing weight in the whole integrated financial framework, so this minor financing weight can be used to leverage private finance sector. This combination of finance instruments aims to provide sustainable financing for SDGs. This paper presents the process to reach a sustainable financing mechanism of SDGs in Albania. Additionally, it presents the tools, like Development Finance Assessment (DFA) and Integrated National Financing Frameworks (INFFs) that lead the country to link finance with results for delivering the SDGs. The paper provides a methodological approach, among others, to support SDGs sustainable financing in order to reach the SDGs targets. This research might bring implications for other developing countries in relation to financing SDGs.
Are Slovenian Manufacturing Companies Ready for Industry 4.0?
Authors: Palčič Iztok , Kovič Klemen
Published: July 2023

This paper focuses on the diffusion of digital technologies in Slovenian manufacturing companies with respect to the concept of Industry 4.0. We present an Industry 4.0 readiness index and assess the Industry 4.0 readiness of Slovenian manufacturing companies. This index focuses on the use of selected digital technologies and their distribution within specific technology fields. The results are based on a sample of 141 Slovenian manufacturing companies whose data was collected as part of the latest edition of the European Manufacturing Survey 2022. The results show that the use of included digital technologies differs between companies and that the majority of manufacturing companies is still far away from the highest Industry 4.0 readiness levels.
Multidisciplinarity and Interdisciplinarity: Key Elements for Teaching Environmental Sustainability at Economic and Business Faculties
Authors: Radonjič Gregor , Denac Matjaž
Published: July 2023

The fact is that topics related to sustainable development are becoming an important integral part of curricula in economics and business higher education. However, the question arises how to include the field into educational practices, what competences and knowledge are required for different study courses (both to lecturers and students) and how to understand interdisciplinarity within different faculty departments. In this paper, we present 30 years of experiences of teaching sustainability topics with the emphasis on environmentrelated issues given by the members of the Department of technology and entrepreneurial protection at the Faculty of Economics and Business in Maribor. Several decades of experiences confirm that multi- and interdisciplinarity are one of the key features in the education of economics and business students due to the ever-increasing complexity of environmental issues that companies face in practice. In order to demonstrate the importance of multi- and interdisciplinarity in teaching environmental sustainability, we present two cases given in our current courses: carbon footprint calculation and evaluating of ''greener'' products with the application of software tools and databases (like Life Cycle Assessment tools).
Sustainable Financing – European Legislative Framework and Impact on the Economy
Authors: Gongeta Sanja , Draganić Stjepan , Gongeta Vedran
Published: July 2023

The financial sector is not immune to the risks caused by climate change and environmental degradation, and it follows trends and improves its contribution to sustainability. Strengthening economic and financial resilience to sustainability risks is one of the priorities of legislators at the global level. Sustainable financing as one possible solutions refers to the practice of providing funding to projects or businesses that promote sustainability, including social, environmental, and economic sustainability and the paper analyses its impact on economic development and increasing competitiveness. The aim of sustainable financing is to support projects that not only generate financial returns, but also have a positive impact on society and the environment. The paper is based on the analysis of empirical data and critical review of literature. Empirical data for the study are the secondary data retrieved from European Central Bank and European regulations.
Emotional Intelligence Training Tools for Business
Authors: Fedorova Yuliia , Pilková Anna , Mikuš Juraj , Holienka Marian
Published: July 2023

This study aims to present practical tools for developing emotional intelligence (EI) in training entrepreneurs, managers and business students. The study proposes innovative tools that allow consistent development of each part of the 4- component instrumental model for emotional intelligence development. The systematic approach is based on contemporary theoretical research and uses applied software. An alarm clock is one of the promising Emotional Intelligence Training Tools. Alarm clocks are created using chatbots in the Smart Sender program. The dynamics of emotional intelligence development of entrepreneurs, managers and business students is tracked through questionnaires and building emotional intelligence profiles. The practical value of Emotional Intelligence Training Tools lies in their simplicity and effectiveness in an educational environment.
The Use of Biofuels as an Example Solution to Energy Security Challenges in Poland
Authors: Dziubek Ireneusz Teodor , Manasterska Tatiana
Published: July 2023

The aim of this article is to critically analyse the problem of expected changes in the field of energy security. The events of the war in Ukraine have brought the issue of energy security management to new levels of business, political and economic considerations. Energy security is most often understood as such a state of the economy that ensures that consumers' demand for fuel and energy is met - economically, technically and socially. Separate studies indicate that the supply of the energy system should be flexible and diverse. Any negative impact of the energy sector must be short-lived, minor and quickly minimized. The ongoing analysis and inference carried out by the authors of this article showed that the EU's intentions and projects, including in Poland, can be disrupted by the fact that each country develops its economy and manages energy in its own way. It was shown that biofuels will be an important element in ensuring Poland's future energy security. On such a basis of research conclusions, a practical implication was derived that, given the assumed costs of the energy transition and the requirements of the "Green Deal," preparatory activities should begin in the country now.
Observation of Single-Molecule Raman Spectroscopy Enabled by Synergic Electromagnetic and Chemical Enhancement
Authors: Li Zhi-Yuan , Yang Haiyao , Hong Lihong , Mo Haoran
Published: July 2023

Raman spectroscopy is a powerful tool to detect, analyze and identify molecules. It has been a long-history pursuit to push the detection limit of Raman spectroscopy down to the fundamental single-molecule (SM) level. Due to the tiny cross section of intrinsic Raman scattering of molecule, some enhancement mechanisms of light-matter interaction must be implemented to levitate the Raman scattering intensity by a huge number of ~ 14–15 orders of magnitude, to the level comparable with the molecule fluorescence intensity. In this work we report unambiguous observation of single-molecule Raman spectroscopy via synergic action of electromagnetic and chemical enhancement for rhodamine B (RhB) molecule absorbed within the plasmonic nanogap formed by gold nanoparticle sitting on the two-dimensional (2D) monolayer WS2 and 2 nm SiO2 coated gold thin film. Raman spectroscopy down to an extremely dilute value of 10− 18 mol/L can still be clearly visible, and the statistical enhancement factor could reach 16 orders of magnitude compared with the reference detection sample of silicon plate with a detection limit of 10− 2 mol/L. The electromagnetic enhancement comes from local surface plasmon resonance induced at the nanogap, which could reach ~ 10–11 orders of magnitude, while the chemical enhancement comes from monolayer WS2 2D material, which could reach 4–5 orders of magnitudes. The synergic implementation and action of these two prestigious Raman scattering enhancement mechanisms in this specially designed 2D material-plasmon nanogap composite nanoscale system enables unambiguous experimental observation of single-molecule Raman spectroscopy of RhB molecule. This route of Raman enhancement devices could open up a new frontier of single molecule science, allowing detection, identification, and monitor of single molecules and their spatial-temporal evolution under various internal and external stimuli.
The relation between religious attitude, psychological resilience and hope in female heads of households in Sirjan, Iran
Authors: Sadeghi Reza , Abolghaseminejad parniya , Borhaninejad Vahidreza , Amir Mohammad Moqaddasi , Zeidabadi Batool
Published: July 2023

Background
Female heads of households struggle with many problems and may encounter a lot of psychological pressure. Religious attitude may alleviate psychological pressures, and improve resilience. This study aimed to determine the relation between religious attitude, psychological resilience and hope in female heads of households in Sirjan in 2021.
Methods
This descriptive-analytical study used convenience sampling to enroll 400 eligible female heads of households covered by the Imam Khomeini relief committee in Sirjan in 2021. The Golriz-Barahani religious attitude questionnaire, the Connor-Davidson resilience scale, and the Snyder’ hope scale were used to collect information. Data were analyzed using SPSS 26, and descriptive statistics and Spearman's correlation coefficients were reported.
Results
The mean age of the participants was 43.22 ± 9.78 years. The mean scores of religious attitude, resilience, and hope were 66.03 ± 7.57 (from 100), 75.74 ± 8.93 (from 100), and 32.22 ± 3.50 (from 60), respectively. The results showed a significant positive relation between religious attitude and psychological resilience (P < 0.001) and between religious attitude and hope (P < 0.001).
Conclusions
Increasing religious attitude may help improve resilience and hope among female heads of households.
Hepatic ketogenesis regulates lipid homeostasis via ACSL1-mediated fatty acid partitioning
Authors: Ramakrishnan Sadeesh , Mooli Raja Gopal Reddy , Han Yerin , Fiorenza Ericka , Kumar Suchita , Bello Fiona , Nallanagulagari Anoop , Karra Shreya , Teng Lihong , Jurczak Michael
Published: July 2023

Liver-derived ketone bodies play a crucial role in fasting energy homeostasis by fueling the brain and peripheral tissues. Ketogenesis also acts as a conduit to remove excess acetyl-CoA generated from fatty acid oxidation and protects against diet-induced hepatic steatosis. Surprisingly, no study has examined the role of ketogenesis in fasting-associated hepatocellular lipid metabolism. Ketogenesis is driven by the rate-limiting mitochondrial enzyme 3-hydroxymethylglutaryl CoA synthase (HMGCS2) abundantly expressed in the liver. Here, we show that ketogenic insufficiency via disruption of hepatic HMGCS2 exacerbates liver steatosis in fasted chow and high-fat-fed mice. We found that the hepatic steatosis is driven by increased fatty acid partitioning to the endoplasmic reticulum (ER) for re-esterification via acyl-CoA synthetase long-chain family member 1 (ACSL1). Mechanistically, acetyl-CoA accumulation from impaired hepatic ketogenesis is responsible for the elevated translocation of ACSL1 to the ER. Moreover, we show increased ER-localized ACSL1 and re-esterification of lipids in human NASH displaying impaired hepatic ketogenesis. Finally, we show that L-carnitine, which buffers excess acetyl-CoA, decreases the ER-associated ACSL1 and alleviates hepatic steatosis. Thus, ketogenesis via controlling hepatocellular acetyl-CoA homeostasis regulates lipid partitioning and protects against hepatic steatosis.
Knowledge and Associated Factors towards Early Management of Acute Myocardial Infarctions among Nurses Working in the Adult Emergency Department of Selected Public Hospitals in Addis Ababa, Ethiopia
Authors: Kebede Roba , Kefyalew Merahi , Michael Mebrat , Kebede Kumela
Published: July 2023

Background
Acute myocardial infarction is a life-threatening condition and the leading cause of death that influences the individual's physical, psychological, and social dimensions. The increasing burden of myocardial infarction remains a low priority for public health in many countries. So, it is essential to determine the nurse’s knowledge of early management of myocardial infarction for life-threatening. Therefore, this study aimed to assess the knowledge and associated factors toward early management of acute myocardial infarction among nurses working in adult emergency rooms at selected public hospitals in Addis Ababa, Ethiopia. 2022
Method
An institution-based cross-sectional study design was conducted with 168 nurses working in adult emergency at selected public service hospitals in Addis Ababa, Ethiopia. The data were collected from April 15 to May 15, 2022 by self-administered questionnaire. The data were analyzed by using SPSS version 26 software.
Result
A total of 168 participants were included in the study, out of which 74(44%) participants had good knowledge of early management of acute myocardial infarction. In multivariable logistic regression analysis showed BSc degree (AOR = 0.06 95%CI (0.007–0.528)), Diploma nurses (AOR = 0.05 95%CI (0.004–0.48)), management guideline of acute myocardial infarction in a unit (AOR = 2.24 95%CI (1.02–4.9)), and training toward early management of acute myocardial infarction (AOR = 4.03 95%CI 1.68–9.69) were the factors significantly associated with the level of ED nurses knowledge towards early management of AMI.
Conclusion and Recommendation:
This study result indicates participants had inadequate knowledge of early management of acute myocardial infarction among nurses working in an adult emergency. Generally, I recommend that the upgrading education level the program must give for ED nurses, training programs should be provided for ED nurses on early AMI management, and AMI management guidelines/standard tools should be designed to improve ED nurses' knowledge.
C α −ruled surfaces respect to direction curve in fractional differential geometry
Authors: Has Aykut , Yılmaz Beyhan , Ayvacı Kebire Hilal
Published: July 2023

Conformable fractional calculus is a relatively new branch of mathematics that seeks to extend traditional calculus to include non-integer order derivatives and integrals. This new form of calculus allows for a more precise description of physical phenomena, such as those related to fractal geometry and chaos theory. It also offers new tools for solving problems in physics, engineering, finance, and other areas. By using conformable fractional calculus, researchers can gain insight into the behavior of systems that would otherwise be difficult or impossible to analyze. In this article, we will discuss the fundamentals of conformable fractional calculus and its applications in various fields. For this purpose ruled surfaces are studied with conformable fractional calculus. The ruled surface is rearranged concerning the conformable surface definition and geometric properties are investigated.
MSC Classification: 53A04 , 53A05 , 26A33
A Narrative Case History of Distance Education Before, During, and After COVID-19 in China and Iran
Authors: Keshavarz Mohsen , Yuan Li
Published: July 2023

Educational hub refers to centres of excellence in higher education and research whose aims are to provide high-quality education for both national and international students to enhance the competitiveness of the country. These educational hubs provide an opportunity for knowledge exchanges and innovation in local regions through education and training. In response to the COVID-19 pandemic, rapid shifts were made towards online learning in education around the world. Although the lockdown is over, remote learning will likely play an increasingly prominent role in education. The adoption of scaled remote learning during the pandemic provided evidence of the importance of online learning. They offer an insight into global society, helping prepare students for an increasingly interconnected world by facilitating links between different regions. Educational hubs can be tied to distance learning and are successful in attracting international students when offering a combination of distance learning methods and innovative programs. This paper examines the phenomenon of educational hubs in higher education for international education through online learning with digital technology. New opportunities for online and distance learning within the definition of educational hubs are analyzed, and three online and blended learning models that reflect the development of educational hubs based on COVID-19 conditions of education are offered. In addition, the successful cases and experiences of distance learning hubs in China and Iran in recent years are described.
Evaluation of the effectiveness of small aperture network telescopes as IBR data sources
Authors:   , Chindipha Stones Dalitso
Published: July 2023

The use of network telescopes to collect unsolicited network traffic by monitoring unallocated address space has been in existence for over two decades. Past research has shown that there is a lot of activity happening in this unallocated space that needs monitoring as it carries threat intelligence data that has proven to be very useful in the security field. Prior to the emergence of the Internet of Things (IoT), commercialisation of IP addresses and widespread of mobile devices, there was a large pool of IPv4 addresses and thus reserving IPv4 addresses to be used for monitoring unsolicited activities going in the unallocated space was not a problem. Now, preservation of such IPv4 addresses just for monitoring is increasingly difficult as there is not enough free addresses in the IPv4 address space to be used for just monitoring. This is the case because such monitoring is seen as a ’non-productive’ use of the IP addresses. This research addresses the problem brought forth by this IPv4 address space exhaustion in relation to Internet Background Radiation (IBR) monitoring. In order to address the research questions, this research developed four mathematical models: Absolute Mean Accuracy Percentage Score (AMAPS), Symmetric Absolute Mean Accuracy Percentage Score (SAMAPS), Standardised Mean Absolute Error (SMAE), and Standardised Mean Absolute Scaled Error (SMASE). These models are used to evaluate the research objectives and quantify the variations that exist between different samples. The sample sizes represent different lens sizes of the telescopes. The study has brought to light a time series plot that shows the expected proportion of unique source IP addresses collected over time. The study also imputed data using the smaller /24 IPv4 net-block subnets to regenerate the missing data points using bootstrapping to create confidence intervals (CI). The findings from the simulated data supports the findings computed from the models. The CI offers a boost to decision making. Through a series of experiments with monthly and quarterly datasets, the study proposed a 95% - 99% confidence level to be used. It was known that large network telescopes collect more threat intelligence data than small-sized network telescopes, however, no study, to the best of our knowledge, has ever quantified such a knowledge gap. With the findings from the study, small-sized network telescope users can now use their network telescopes with full knowledge of gap that exists in the data collected between different network telescopes.
Challenges and Prospects of Eurasian Integration in a Changing World
Authors: Slutsky L. E.
Published: July 2023

The purpose of the study is to analyze the impact of the modern transformation of international economic relations on the integration processes in the Eurasian Economic Union. In accordance with the designated goal, the objectives of the study are: 1. to identify current challenges and threats to Eurasian integration; 2. to assess the prospects for further development of the Eurasian Economic Union and the ability of the integration association to withstand these challenges in the new geopolitical realities.Materials and methods of research. In the process of preparing the article, data from international, interregional and national reports, analytical statistical materials, scientific works of Russian and foreign scientists were used. In the course of the work, statistical methods of analysis of economic phenomena were used, methods of logical and system analysis, dynamic, structural analysis of macroeconomic indexes, interregional analysis of data evaluation, as well as tabular methods of visualization of research results were used.Results. The article analyzes some macroeconomic indexes characterizing the current state and development of the economy of the Eurasian Economic Union as a whole and its member- countries. As a result of the conducted research, the main challenges of Eurasian integration were identified and the prospects and ability of the integration association to withstand these challenges in modern geopolitical conditions were assessed.Conclusion. Eurasian integration is a strategic choice for the Russian Federation, which determines one of the most important directions of development of Russia’s foreign policy. The integration process within the framework of the Eurasian Economic Union has traditionally been accompanied by a number of contradictions, which, depending on many factors, may either intensify or weaken with the increase in global challenges and threats. That is why, at present, it is not possible to fully assess the prospects for further development of Eurasian integration. At the same time, despite the high probability of recession in the largest centers of the world economic system, the Eurasian Economic Union turned out to be one of the integration associations capable to some extent of resisting negative trends in world politics and the economy, and the member-countries of the Eurasian Economic Union managed not only to prevent a large-scale economic downturn, but also to ensure macroeconomic stability.
Folate-mediated Transport of Nanoparticles across the Placenta
Authors: Kalashnikova Irina , Patrikeeva Svetlana , Nanovskaya Tatiana N. , Andreev Yaroslav A. , Ahmed Mahmoud S. , Rytting Erik
Published: July 2023

Background:

In this study, a prototype of a targeted nanocarrier for drug delivery for prenatal
therapy of the developing fetus was developed and examined in vitro and ex vivo. The folate
transport mechanism in the human placenta was utilized as a possible pathway for the transplacental delivery
of targeted nanoparticles.

Methods:

Several types of folic acid-decorated polymeric nanoparticles were synthesized and characterized.
During transport studies of targeted and non-targeted fluorescent nanoparticles across the placental
barrier, the apparent permeability values, uptake, transfer indices, and distribution in placental tissue
were determined.

Results:

The nanoparticles had no effect on BeWo b30 cell viability. In vitro, studies showed significantly
higher apparent permeability of the targeted nanoparticles across the cell monolayers as compared
to the nontargeted nanoparticles (Pe = 5.92 ± 1.44 ×10-6 cm/s for PLGA-PEG-FA vs. 1.26 ± 0.31
×10-6 cm/s for PLGA-PEG, P < 0.05), and the transport of the targeted nanoparticles was significantly
inhibited by excess folate. Ex vivo placental perfusion showed significantly greater accumulation of the
targeted nanoparticles in the placental tissue (4.31 ± 0.91%/g for PLGA-PEG-FA vs. 2.07 ± 0.26%/g for
PLGA-PEG).

Conclusion:

The data obtained suggested different mechanisms for the uptake and transplacental transfer
of targeted versus nontargeted nanoparticles. This targeted nanoformulation may be a promising
strategy for fetal drug therapy.
The Potentials of Robusta Coffee Seed Extract as Antioxidant on Kidney Histopathology in Mice Exposed to Monosodium Glutamate
Authors:   Mahasiswa Fakultas Kedokteran Hewan, Universitas Airlangga Surabaya, Wisudawati Feby Dwi , Hidajati Nove , Fikri Faisal , Santoso Kuncoro Puguh , Saputro Amung Logam , Purnama Muhammad Thohawi Elziyad
Published: July 2023

The purpose of this study was to determine the potential of administration robusta coffee extract as an antioxidant on the renal histopathology in mice exposed to monosodium glutamate (MSG) orally. This study used 20 adult male rats with Balb C strain divided into 5 experimental groups, namely K + (MSG 0.12 mg / head and Vitamin C 6 mg/mice), K- (MSG 0.12 mg/mice and Sodium carboxymethyl cellulose (CMC Na) 0,1 ml/mice), P1 (MSG 0.12 mg/mice and Robusta coffee extract 0.1 mg/mice), P2 (MSG 0.12 mg/mice and Robusta coffee extract 0.2 mg/mice), and P3 (MSG 0.12 mg/mice and 0.4 mg Robusta coffee extract mg/mice). The experimental group was treated every day at intervals between MSG and Vitamin C, CMC Na, and Robusta coffee extract for 60 min, the treatment was carried out for 42 days. Kidney histopathology scores were analyzed using the Saphiro-Wilk and Levene test to evaluate homogeneity, followed by the Kruskal Wallis test. The results of the Saphiro Wilk and Levene statistical analysis obtained p<0.05, thus the data continued with the Kruskal Wallis test scores of kidney cell damage obtained 0.043 which showed that the data were significant. The mean score of kidney cell damage in the treatment groups was K+ 1.60; K- 1.63; P1 1.70; P2 1.63; and P3 1.73. The conclusion is that Robusta coffee bean extract did not show a decrease in kidney cell damage that was different between treatment groups. Further research is needed to find out about the effect of different dosages of Robusta Coffee Extract to different organs
The Correlation of Administrative and Disciplinary Responsibility of Arbitration Managers
Authors:   National Research University Higher School of Economics, Volkov Maxim V.
Published: July 2023

In the article the problem of correlation of administrative and disciplinary responsibility of insolvency ofﬁcers. Legal regulation of administrative and disciplinary responsibility of insolvency ofﬁcers was analyzed and compared. The author argues the possibility of removing from the sphere of administrative responsibility of relations, which are the subject of disciplinary control of self-regulatory organizations of arbitration managers.
Natural Human Freedoms as the Basis of Legal Regulation
Authors:   National Research University Higher School of Economics, Izotov Yuri G.
Published: July 2023

The article provides a new approach to understanding natural human rights. The author reviews the existing concepts of natural law: ancient philosophers, religious ﬁgures of the Middle Ages and the New Age, philosophers of the Enlightenment, I. Kant, the views of modern lawyers, reﬂected in fundamental international documents and national constitutions. It is concluded that the existing concepts are based on assumptions, many of their provisions are outdated and often contradict each other, and the content of the natural human rights themselves is not disclosed. The author is critical of the opinion that natural law is morality or divine law. Instead, it is proposed to build a concept based on the biological characteristics of the human body. To substantiate the new approach, the author applies the method of R. Descartes — denial until the very denial becomes absurd. Thanks to this method, an objective basis was found — «a person exists while he lives», from which further reasoning is conducted. The article provides a logically justiﬁed and integral system of natural human rights, which the author calls “human natural freedoms”. These include natural freedoms: life, consumption, labor, worldview, knowledge and selfdefense. The author proves that they are inalienable, absolute, independent in use and permanent. The article also shows how the objectively existing system of natural human freedoms interacts with positive law. The author notes that the role of such a “bundle” is played by the principles of regulation, which include: universality, equality and fairness. In conclusion, a conclusion is made about the theoretical and practical signiﬁcance of the presented concept.