bluuebunny/crossref_metadata_2025 huggingface dataset:
O manejo do aleitamento materno em uma maternidade referência na região
Authors: Moretti Paola , Kersten Richard , Garcia Cristina Klein Keunecke
Published: November 2024

Objetivo: Relatar a importância da comunicação do profissional de saúde com o paciente para obter-se sucesso no aleitamento materno. Relato de experiência: O estágio ocorreu durante 5 semanas em uma maternidade com Banco de Leite Humano, o qual possui padrão ouro de qualidade. Os alunos passaram por 4 setores diferentes: Alojamento conjunto, Sala de Parto, Banco de Leite Humano e Unidade de Cuidado Intermediário Neonatal Convencional. Dessa forma, foi estimulado a prática e o conhecimento do manejo aos recém-nascidos, assim como o desenvolvimento de habilidades para instruir e ajudar as lactantes na amamentação. Considerações finais: No decorrer do estágio e em corroboração com a literatura, evidenciou-se que a escassa informação acerca do aleitamento materno, contribui para o desmame precoce. Além disso, fatores emocionais e variações anatômicas podem estar envolvidos neste processo. Sendo assim, evidencia-se a importância da capacitação de todos os profissionais de saúde frente ao tema, para encorajar e apoiar as mulheres durante o período da amamentação.
Cardiopatia chagásica e exercício físico aeróbico
Authors: Santos Raissa Moreira Camarão dos , Carvalho Thalissa Fernandes , Chaves Elem Cristina Rodrigues , Zaffalon Júnior José Robertto , Aarão Tinara Leila de Souza , Lima Patrícia Danielle Lima de , Sousa Smayk Barbosa
Published: November 2024

Objetivo: Avaliar os efeitos do exercício físico aeróbico na função cardíaca, na capacidade de exercício e qualidade de vida de pacientes com cardiopatia chagásica. Métodos: Foi elaborado uma revisão integrativa na qual utilizou como referência estudos encontrados nas bases de dados PubMed, Scopus e Web of Science, em sete anos. Resultados: Os anos de 2019 e 2022 se destacam com a maior frequência de publicações (23,08%). Os resultados indicam que o exercício físico aeróbico pode ser uma estratégia terapêutica complementar eficaz, contribuindo para a melhoria da função cardíaca, aumento da capacidade de exercício e melhora da qualidade de vida dos pacientes. No entanto, destaca-se a necessidade de mais estudos para padronizar protocolos de exercício e identificar os mecanismos específicos pelos quais o exercício beneficia pacientes com cardiopatia chagásica. Considerações finais: Apesar das limitações existentes, a prática de exercício físico aeróbico apresenta um potencial significativo para a reabilitação cardíaca em indivíduos acometidos pela doença de Chagas, devendo ser considerada como parte do plano de tratamento.
Percutaneous microwave ablation of a transgenic large animal porcine liver tumor model after intra-arterial embolization
Authors: Rice Samuel L. , Berry-Tony Sagine , Benjamin Jamaal , Gómez Muñoz Fernando , Alnablsi Mhd. Wisam , Beets-Tan Regina
Published: November 2024

Objectives:

Percutaneous ablation with microwave ablation (MWA) successfully treats hepatic tumors (HTs) up to 3 cm in size when appropriate margins are achieved. MWA is limited when treating larger HT due to the disbursement of heat from adjacent tissue and vasculature. Embolization before MWA can achieve a larger ablation zone (AZ); however, no evaluation has been performed to assess the influence of proximal or distal embolization on AZ.

Material and Methods:

Using a transgenic porcine liver tumor model, angiography and embolization of HT were performed with lipiodol or different-sized particles, ranging from 40 to 1200 µm to complete vascular occlusion followed by MWA for 4 min at 65 watts with subsequent ex vivo assessment of AZ.

Results:

AZ volume using 40 µm, 100 µm, and 300–500 µm microparticles were significantly larger than for the control, non-embolization group (mean ± standard deviation: 40 µm: 17.48 cm3 ± 1.22, P ≤ 0.001; 100 µm: 14.81 cm3 ± 0.43, P ≤ 0.001; and 300–500 µm: 12.16 cm3 ± 0.8, P ≤ 0.001 compared to 6.06 cm3 ± 2.02 in the control group.

Conclusion:

Distal embolization with smaller particles produced significantly larger AZ in an in vivo liver tumor when compared to no embolization control, lipiodol, or proximal large particle embolization.
Precision medicine for patients with salivary gland neoplasms: Determining the feasibility of implementing a next-generation sequencing-based RNA assay in a hospital laboratory
Authors: Sura Gloria Hopkins , Hsu Jim , Mody Dina R. , Thomas Jessica S.
Published: November 2024

Objective:

Diagnosing neoplasms of the salivary gland is challenging, as morphologic features of these tumors are complex, and well-defined diagnostic categories have overlapping features. Many salivary gland neoplasms are associated with recurrent genetic alterations. The utilization of RNA-based targeted next-generation sequencing (NGS) panels for the detection of cancer-driving translocations and mutations is emerging in the clinical laboratory. Our objective was to conduct a proof-of-concept study to show that in-house molecular testing of salivary gland tumors can enhance patient care by supporting morphologic diagnoses, thereby improving therapeutic strategies such as surgical options and targeted therapies.

Material and Methods:

Residual formalin-fixed paraffin-embedded salivary gland neoplasm specimens from a cohort of 17 patients were analyzed with the Archer FusionPlex Pan Solid Tumor v2 panel by NGS on an Illumina NextSeq550 platform.

Results:

We identified structural gene rearrangements and single nucleotide variants in our patient samples that have both diagnostic and treatment-related significance. These alterations included PLAG1, MAML, and MYB fusions and BRAF, CTNNB1, NRAS, and PIK3CA mutations.

Conclusion:

Our RNA-based NGS assay successfully detected known gene translocations and mutations associated with salivary gland neoplasms. The genetic alterations detected in these tumors demonstrated potential diagnostic, prognostic, and therapeutic value. We suggest that incorporating in-house ancillary molecular testing could greatly enhance the accuracy of salivary gland fine needle aspiration cytology and small biopsies, thereby better guiding surgical decisions and the use of targeted therapies.
A review on the school dental services in Sri Lanka
Authors: Samarawickrama Mangala , Dissanayake Asela Kumara , Nishanthi S A Pamila
Published: November 2024

The school dental program in Sri Lanka is operated under the Ministry of Health (MOH) in collaboration with the Ministry of Education to improve the oral health of schoolchildren. The Oral Health Unit of the Family Health Bureau (FHB), which is under the MOH, is the national focal point for the provision of school dental services. This program provides health promotion activities to prevent the most common oral diseases among schoolchildren and treatment of existing diseases. Preventive measures focused on schoolchildren are the most cost-effective measure to improve the oral health of schoolchildren and will reduce the cost of oral healthcare in adulthood. School dental therapists (SDTs) play an important role at the point of service delivery by executing oral health promotion, screening, preventing, treating, and referring for an appropriate level of care. The objective of this review is to explore the school dental services provided under the Oral Health Unit to provide recommendations for improvement. Data collection was done from July 2023 to August 2023. Qualitative data were collected through semistructured key informant interviews. In addition, a desk review was done to collect secondary data available at the Oral Health Unit, FHB, to explore the present situation of the services. Data were analyzed using the content analysis method. “Inadequacy of service coverage” was identified as the main problem in school dental services in Sri Lanka, leading to a higher prevalence of untreated oral diseases among schoolchildren. The root causes for this problem were mainly human resource related. Other root causes were related to financial support, infrastructure, resource allocation, and processes. This review proposes human resource-related strategies to address those root causes. This recommends increasing the human resources for the service coverage, motivating the SDTs and developing their capacity to deliver the service at the point of care.
A clinical study to evaluate the efficacy of yogaraja rasayana in pandu roga (w.s.r. to iron deficiency anemia)
Authors: Mishra Manish , Dwivedi K. K. , Gupta Kanchan , Kumar Amit
Published: November 2024

Objectives:

To evaluate the efficacy of Yogaraja rasayana in pandu.

Materials and Methods:

A non-randomized and open single arm study was conducted on 100 patients suffering from pandu.

Results:

The trial drug showed encouraging results in the overall health status of selected cases of pandu [with special reference (w.s.r.) iron deficiency anemia (IDA)] with >75% improvement in 61 cases and >50% improvement in 36 patients.

Conclusion:

Yogaraja rasayana is an unique herbo-mineral combination containing iron rich content ‘mandoor’ along with other herbal drugs helps in increasing the hemoglobin percentage in cases of pandu.
Techno-economic analysis and optimisation of grey and green methanol synthesis using flowsheet automation and surrogate modelling
Authors: Andreasen Anders , van Baten Jasper
Published: November 2024

Recognizing methanol's versatile role as a chemical precursor and energy carrier, the study addresses its traditional production from fossil fuels and the associated challenges in pivoting to green alternatives due to the cost of green hydrogen. The research focuses on techno-economic analysis and optimization, employing a validated chemical process simulation tool integrated with economic analyses, reflecting CAPEX and OPEX models, and considering heat recovery to promote self-sufficiency. The study compares grey (traditional syngas) and green (biogenic CO$_2$ and green hydrogen) methanol production pathways while also optimizing process factors, such as feed pressure, purge rate, temperature and catalyst volume, to achieve cost-effectiveness. In green methanol production specifically, the paper finds that optimal conditions are slightly milder than for grey methanol, highlighting the importance of process variables like purge rate given the high cost of green hydrogen. Still with current price level of hydrogen from electrolysis the levelised cost of methanol is several times more expensive via direct hydrogenation compared to production from fossil syngas. Results from the simulation-driven optimization underline the delicate balance between various objectives, such as minimizing costs or maximizing output, and demonstrate instances of pareto optimality. This study thus contributes with an integrated assessment of methanol production techniques, utilizing process simulation, economic evaluation, and heat integration for both grey and green methanol, aiming to pave the way for more sustainable chemical processes in the industry.
In situ neutron reflectometry reveals the interfacial microenvironment driving electrochemical ammonia synthesis
Authors: Niemann Valerie Anne , Doucet Mathieu , Benedek Peter , Deissler Niklas Henrik , Mygind Jon Bjarke Valbaek , Lee Sang-Won , Rios Amador Isabela , Willoughby Wrayzene , Chorkendorff Ib , Nielander Adam , Tarpeh William , Jaramillo Thomas
Published: November 2024

Electrified interfaces are critical to the performance of energy systems and often demonstrate substantial complexity under operating conditions. Nanoscale understanding of the interfacial microenvironment, i.e., the solid electrolyte interphase (SEI), in lithium-mediated nitrogen reduction (Li-N2R) is key for realizing efficient ammonia (NH3) production. Herein, we have used time-resolved neutron reflectometry (NR) to observe SEI formation under Li-N2R conditions. We found that LiBF4-based electrolyte provided a substantially more well-defined SEI layer than previous SEI NR interrogation that used LiClO4, highlighting the underlying chemistry that dictates electrolyte design and enabling new NR-based studies. Using in situ neutron reflectometry, we found the LiBF4-derived SEI under Li-N2R conditions comprises a thick, diffuse outer layer and a thin, compact inner layer at low current cycling (<2 mA/cm2), revealing a structure which ex situ studies have not been able to probe. Increased current cycling and sustained current cycling led to the merge of the layers to a single-layer SEI. We used isotope contrast methods with d6-EtOH and d8-THF to drive time-resolved tracking of SEI growth at low current cycling, revealing that the proton donor modifies the inner layer, and the solvent modifies the outer layer. Li dendritic growth was observed in the absence of a proton donor. Neutron absorption also indicated the presence of boron in the SEI, underscoring the value of neutron-based interrogation. Our results inform Li-based systems and reaction microenvironments, and these methods can be applied broadly to interfacial energy technologies.
Long-distance charge transport between cytochrome c and complex III is mediated by protons and reactive oxygen species
Authors: Lagunas Anna , M. J. Gomila Alexandre , Nin-Hill Alba , Guerra-Castellano Alejandra , Pérez-Mejías Gonzalo , Samitier Josep , Rovira Carme , De la Rosa Miguel A. , Díaz-Moreno Irene , Gorostiza Pau
Published: November 2024

Electron transfer (ET) between redox proteins is an essential process in the respiratory and photosynthetic transport chains. While intra-protein ET is well characterized, the experimental methods to investigate inter-protein ET are limited by the presence of the solvent and by the transient nature of the protein-protein interaction and ET event, which are averaged in protein ensembles. Wiring precisely oriented redox protein partners to the nanoscale electrodes of an electrochemical scanning tunneling microscope allows to record the time- and distance-dependence of the current flowing between them. These methods have revealed that the current flowing between individual protein pairs extends much beyond tunneling distances and that it is electrochemically gated. However, the mechanism of this process, and especially the identity of the charge carriers in the aqueous solution, remains to be elucidated. To determine the species involved in long distance charge transport between the redox partner proteins Cc and Cc1 of the respiratory chain, we have performed recordings as a function of pH, in heavy water solutions, and in degassed solutions. We observe that the spatial span and electrochemical gating of long-distance currents are reduced at high pH. Currents are also less extended in heavy water and at low oxygen concentration. Using the experimental structures of oxidized and reduced Cc and pKa calculations, we identify residues that can switch their availability to form hydrogen bonds with water and/or engage in proton-coupled electron transfer reactions. Overall, our results show that long distance currents between cytochrome c (Cc) and cytochrome c1 (Cc1) through the aqueous solution are assisted by superoxide anions and by protons, and we discuss possible molecular mechanisms and their relevance for interprotein ET.
Comunicación para el desarrollo y trascendencia social: una revisión narrativa centrada en procesos sociales
Authors: Quispe-Borda Wenceslao , Quispe-Olano Jaime Grossby , Colán-Hernández Bryam-Alejandro , Colina-Ysea Félix José
Published: November 2024

La comunicación para el desarrollo (CpD) es una disciplina que busca promover el cambio social mediante el uso estratégico de los medios de comunicación y el diálogo participativo. Se basa en la premisa de que la comunicación no es solo una herramienta para difundir información, sino un proceso esencial para facilitar la participación activa de las comunidades ante su propio desarrollo. Este artículo presenta una revisión narrativa de la literatura sobre la CpD, con el objetivo de identificar los principales enfoques teóricos y metodológicos que han abordado este tema, así como las principales limitaciones y desafíos que enfrenta la investigación en este campo. Para ello, se analizaron cuarenta y seis documentos seleccionados mediante la búsqueda en las bases de datos Scopus, SciELO, Redalyc, Latindex y Google Scholar. Los resultados han demostrado que la mayoría de los estudios adoptan una perspectiva cualitativa y participativa, enfocada en el análisis de casos específicos de la CpD en diferentes contextos geográficos y temáticos. Asimismo, se han identificado cuatro dimensiones clave para comprender los procesos sociales que intervienen en la CpD: la participación, el empoderamiento, el diálogo y la acción colectiva. Finalmente, se discuten las implicaciones teóricas y prácticas de estos hallazgos y se proponen algunas recomendaciones para futuras investigaciones.
The Impact of Company Size, Capital Intensity, Litigation Risk and Managerial Ownership on Accounting Conservatism
Authors: Hartanto Laura , Nilamsari M. Devitia Putri
Published: November 2024

Accounting conservatism is a cautious reaction to dealing with uncertain matters in the Company. This research aims to determine the influence of company size, capital intensity, litigation risk, and managerial ownership on accounting conservatism. This research is quantitative descriptive research that uses multiple linear regression analysis. The population in this study is manufacturing companies registered on the BEI in 2020-2022, and the sampling method used in this research is purposive sampling, where it is known that the research sample is 94 companies registered on the BEI. The research results show that the variables of company size, litigation risk, and managerial ownership have a positive and significant effect on accounting conservatism. Meanwhile, the capital intensity variable has an insignificant positive effect on accounting conservatism. Investors, potential investors and creditors are advised to be more careful with the information presented in financial reports and to be able to pay attention to published annual financial reports to determine the quality of company profits when making decisions. Referring to the low value of the coefficient of determination, it is hoped that further research can add variables or use other variables outside the model
The Interplay of Organizational Culture and Governance in Enhancing Sustainability Performance
Authors: Abdulrahim Mohamed Omar , Sukoharsono Eko Ganis , Setyarini Any , Subekti Imam
Published: November 2024

It seems that Indonesia still lacks understanding about the disclosure of sustainability. Furthermore, it is believed that socioeconomic, cultural, governance and environmental challenges are crucial to the success of a business. The influence of corporate governance and organizational culture on sustainability performance, with strategic posture acting as a moderating variable, leads to intriguing issues that warrant further analysis. This study's population consists of all companies listed on the Indonesia Stock Exchange. Purposive sampling is used as a technique in this study. The company's website, which includes information from 2009 to 2018, was sourced from www.idx.co.id and other pertinent sources. Data collection was done, and Warp PLS algorithms were employed for the analysis method. After analyzing and debating the data, the following conclusion was reached: corporate governance and organizational culture greatly impact sustainable performance. When examining the impact of corporate governance and organizational culture on sustainability performance, strategic posture may act as a moderating factor
Supporting justice in Local Government: Climate Response in Aotearoa New Zealand
Authors: Diprose Gradon , Bond Sophie , Stephenson Janet , Kawharu Merata
Published: November 2024

While climate justice concerns are increasingly incorporated into policy at international scales, there is less research on climate justice and policy at local scales. Recognising how structural inequalities intersect with climate change influences how rights, responsibilities, distribution of resources and procedures for adaptation are understood and implemented. We describe how some local governments in Aotearoa New Zealand are using recognition practices to improve their understanding of the impacts of climate change, and re-allocating resourcing so mana whenua and communities are better able to participate in climate adaptation procedures. We suggest national policy and legislative changes that could support local governments’ climate justice recognition practices.
Drawing upon Covid-19 lessons to equip Aotearoa New Zealand to take bolder climate action
Authors: Peacocke Heather , Major Linda , Milfont Taciano L.
Published: November 2024

This article highlights challenges in public discourse on climate change in Aotearoa New Zealand and explores why framing and narratives matter. Drawing on the country’s Covid-19 experience, it shows how narratives can help unlock climate action (both mitigation and adaptation). It proposes improving climate communications by providing structures to support sense-making and decision making, with more specificity around societal and individual actions. This will give people, businesses and communities more agency to respond to climate change. By fostering narratives that are hopeful, practical and people-centred, and that relate to people’s needs and aspirations, it is possible to build more momentum around climate action.
Current Status and Considerations on Endoscopic Diagnosis and Treatment of Subepithelial Microlesions in the Digestive Tract
Authors: Pang Jian , Tian Yongjing , Wu Jingyu , Sun Chen , Jiang Yan , Lei Xinwen , Wang Tengqi
Published: November 2024

The detection rate of subepithelial lesions in the digestive tract, especially microlesions (≤ 1 cm in diameter), has significantly increased. Historically, periodic follow-up or surgical resection has been recommended by scholars. Due to the potential risk of malignancy, regular follow-up carries certain risks, while surgical resection, though effective, is highly invasive with a high risk of complications. With the rapid development of endoscopic techniques, more and more subepithelial lesions in the digestive tract have been successfully treated through endoscopic submucosal dissection and endoscopic full-thickness resection. However, these methods require a high level of skill and are associated with significant costs for surgical instruments and materials. Therefore, it is worth exploring whether a simpler and more efficient treatment can transition patients from observation to proactive treatment. A modified technique combining snare, long transparency cap, and Argon Plasma Coagulation under endoscopy has advantages over traditional methods, such as being simpler to perform, less prone to complications, and more cost-effective. This article reviews the current status and considerations of endoscopic treatment for subepithelial lesions in the digestive tract.
FINANCIAL WELLNESS OF STUDENTS IN EAST JAVA: THE ROLE OF PARENTAL FINANCIAL EDUCATION, FINANCIAL STATUS, FINANCIAL LITERACY, AND FINANCIAL BEHAVIOR
Authors: Asiah Afifah Nur , Haryono Agung , Churiyah Madziatul
Published: November 2024

This study aims to identify the factors influencing the financial wellness of students in East Java. The factors examined include parental financial education, financial status, financial literacy, and financial behavior. This research employs a quantitative approach involving 384 students from various universities in East Java. Data were collected through a questionnaire adapted from previously validated instruments. Data analysis was conducted using Structural Equation Modelling – Partial Least Square (SEM-PLS) to determine the influence of each variable on students' financial wellness. The results indicate that parental financial education, financial status, financial literacy, and financial behavior have a significant positive impact on students' financial wellness. Additionally, parental financial education and financial status significantly contribute to students' financial behavior. Meanwhile, financial literacy does not affect students' financial behavior. This suggests that financial behavior mediates the relationship between parental financial education, financial status, and financial wellness.
THE IMPACT OF SELF-CONFIDENCE AND CREATIVITY ON ENTREPRENEURIAL INTENTIONS: THE MEDIATING ROLE OF RISK-TAKING
Authors: Ulfah Maria , Syahrudin Husni
Published: November 2024

This study aims to examine the role of mediating the relationship between the influence of self-confidence, creativity, and risk-taking on entrepreneurial intentions. This study uses PLS-SEM path analysis and quantitative survey. The population consisted of 572 12th-grade vocational students from ten vocational schools in West Kalimantan, Indonesia, chosen via non-probability purposive sampling based on their internship experiences. Participating vocational students are chosen based on their internships in industry, tourism, and other enterprises. The data was obtained using a Likert scale questionnaire and the analysis looked at internal consistency, construct validity, effect size, coefficient of determination, predictive relevance, and path coefficient. Entrepreneurial intentions (EI) are determined by the dominant factor, namely being able to make changes (CR9, λ = 95.40%), and entrepreneurial risks (EI2, λ = 7.30%) are the lowest factor. The ability of the structural model to explain EI is 50.70%, while the creativity variable explains 85.50% (Q² = 0.855) of the phenomena predicted in the field. Furthermore, the mediating role of risk-taking does not increase a significant positive effect on the effect of self-confidence on EI. This conclusion reveals the importance of developing entrepreneurial creativity and entrepreneurial intentions in shaping higher risk-taking behavior in vocational students. Implementing education and training programs that encourage creativity and entrepreneurial intentions can improve students' ability to deal with risks and take innovative steps in entrepreneurship.
THE INFLUENCE OF INFORMAL ECONOMIC EDUCATION ON THE ECONOMIC BEHAVIOR OF INDONESIAN MIGRANT WORKERS MEDIATED BY ECONOMIC AND ENTREPRENEURIAL LITERACY
Authors: Amalina Endah , Haryono Agung , Rokhmani Lisa , Rachmawati Dian
Published: November 2024

Indonesian Migrant Workers (PMI) ideally have a stable and prosperous economic condition characterized by the ability to manage finances wisely through safe and efficient savings and investments. However, this condition differs from most PMIs, who experience economic difficulties after returning to Indonesia. This study aims to confirm the influence of informal economic education, economic literacy, and entrepreneurial literacy on PMI's economic behavior. This research applies Covariance-Based Structural Equation Modeling (CB-SEM) using a quantitative approach with deductive thinking logic. Data were collected through an online survey and analyzed using IBM-SPSS-AMOS 25 to confirm the hypothesis proposed. The results showed that informal economic education, economic literacy, and entrepreneurial literacy positively affected PMI's economic behavior. Economic and entrepreneurial literacy also mediate the relationship between informal economic education and PMI's economic behavior in a partial (partial mediation) manner. The results provide valuable insights for policymakers and job training institutions on involving families to improve economic and entrepreneurial literacy in encouraging PMI's economic behavior.
Ekolojik Çıkarım Yöntemi: 2024 Yılı Ankara Büyükşehir Belediye Başkanlığı Seçimi Oy Geçiş Analizi
Authors: Hasdemir Esra , Çamalan Özge , Üner Mithat
Published: November 2024

Ekolojik çıkarım yöntemi, bireysel verilere erişimin mümkün olmadığı ya da çok zor olduğu durumlarda, toplulaştırılmış düzeydeki verilerden hareketle bireysel düzeydeki verilere yönelik tahminler yapılmasını sağlayan bir yaklaşımdır. Buradan hareketle, çalışma kapsamında, 2024 yılında yapılan Ankara Büyükşehir Belediye Başkanlığı seçimine ait oy geçişleri Rosen, Jiang, King ve Tanner (2001) tarafından geliştirilen ekolojik çıkarım yaklaşımıyla analiz edilmiştir. Söz konusu oy geçişleri, 8×8 boyutunda kontenjans tablosu temelinde yapılan analiz sonucunda hem seçmen sayısı hem de geçiş olasılık matrisi bazında tahmin edilmiş ve yorumlanmıştır. Elde edilen tahminler, Sankey diyagramı çizilerek görselleştirilmiştir. Ankara Büyükşehir Belediye Başkanlığı seçimi temelinde yapılan analiz sonuçlarına göre, 2019 seçimlerinde Adalet ve Kalkınma Partisi (AK Parti) için oy kullanan seçmenin %54’ünün 2024 seçiminde de AK Parti’ye oy verdiği, 2019 yılı seçiminde AK Parti’ye oy verenlerin yaklaşık %20’sinin 2024 seçiminde oy kullanmadığı, %16,6’sının ise Cumhuriyet Halk Partisi (CHP)’ ne oy verdiği tahmin edilmiştir. Aynı analiz sonuçlarına göre, 2019 seçimlerinde CHP yönünde oy kullanan seçmenin %82,7’sinin yeniden CHP’ye oy verdiği, %10,5’inin oy kullanmadığı, %2,1’inin AK Parti’ye oy verdiği belirlenmiştir. Analizin bir diğer bulgusu ise, 2019 seçiminde oy kullanmayan seçmenin %58,8’inin 2024 yerel seçiminde de oy kullanmamayı tercih ettiği, 2019 yılı seçiminde oy kullanmayan seçmenlerin geriye kalan kısmının %23,5’inin CHP’ye, %1,9’unun AK Parti’ye, %7,8’inin diğer partilere, %2,3’ünün Yeniden Refah Partisi (YRP)’ne, %1,1’i ise İYİ Parti’ye oy verdiği şeklindedir.
Prolonged-Release Melatonin for Sleep Disturbances in Autism Spectrum Disorder
Authors: Vivas Eva Arias , Ron Adrián García , Alguacil Elena González , Gascón Marta Bote , de Santos Moreno María Teresa , Cabrera Elsa Santana , de las Cuevas Guillermo Ruiz-Ocaña , Peñas Juan José García , Hoyo Rafael Sánchez-del , Insuga Víctor Soto
Published: November 2024

Purpose: Patients with autism spectrum disorder (ASD) often present with sleep disturbances. We evaluated the effectiveness of pediatric prolonged-release melatonin (PedPRM) in real clinical practice, focusing on a population of complex neuropediatric patients with highly refractory insomnia in Spain.Methods: The patients were aged 2 to 18 years, diagnosed with ASD, had sleep maintenance insomnia and/or early morning awakening insomnia, and were refractory to prior therapy. The starting dose of PedPRM was 2 or 5 mg (increased to 10 mg, if necessary). Evaluation at 6 months consisted of a sleep diary, the Sleep Disturbance Scale for Children (SDSC), the Pediatric Daytime Sleepiness Scale (PDSS), and the Clinical Global Impression Scale of Improvement (CGI-I) and Severity (CGI-S).Results: The median age of the 23 patients was 11.0 years, 56.5% were male, 73.9% had epilepsy, and 78.3% had intellectual disability. One patient discontinued treatment. The mean total sleep time did not change significantly. PedPRM improved sleep latency (median 30.0 to 15.0 minutes; P=0.001) and reduced the number of nocturnal awakenings (median 3.00 to 1.0; P<0.001). PedPRM significantly improved PDSS scores (14.6±4.5 to 10.4±3.5; P<0.001) and SDSC total scores (75.1±12.9 to 61.6±10.9; P<0.001). The CGI-I scale improved in 73.3% of patients; 46.7% of patients were normal, borderline, or mildly ill per CGI-S scale at the end of treatment.Conclusion: In real clinical practice, PedPRM significantly improved sleep parameters in patients with ASD who were heavily medicated for comorbidities and were highly refractory to other insomnia treatments.
Diretor de escola: História de vida como possibilidade de compreensão de elementos da gestão escolar
Authors: Marangoni Ricardo Alexandre
Published: November 2024

A história de vida é uma importante fonte de informação sobre a prática profissional. Os estudos realizados sob este referencial podem corroborar com a discussão da formação e trabalho dos profissionais da educação. Assim sendo, o objetivo deste artigo foi descrever e analisar a minha própria trajetória profissional de diretor de escola pública, levantando elementos que possam ajudar no debate da gestão escolar e do trabalho do diretor. A metodologia utilizada se aproxima da abordagem autobiográfica (Ferrarotti, 2010; Passeggi; Souza; Vicentini, 2011 e outros), e as narrativas revelam parte da minha história de vida construída no chão da escola. Concluo com uma reflexão sobre a problemática do pesquisador e pesquisado serem a mesma pessoa, e o reconhecimento de que o diretor escolar comprometido com a gestão democrática e a melhoria da qualidade da educação exerce seu trabalho com muita dificuldade, dadas as tensões, contradições e vicissitudes das políticas educacionais paulistas.
A STUDY: ON PREMARITAL SEXUAL HEALTH BEHAVIOR AMONG THE ADOLESCENT GIRLS IN INDIA
Authors: Pal Manisha
Published: November 2024

This research paper reviews documents that have influenced understanding of premarital sexual health behavior among the adolescent girls in, India. Focus is on premarital sexual behavior and practices among the adolescent groups, which is comparatively raised in India from the last decades, especially in urban areas. In present scenario adolescents are more sexually active than ever before. Among adolescent who are at early age fourteen or younger are more sexually active and faces innumerable health risk due to their unsafe practices. They are more likely to get involved in high-risk sexual behaviors that comprises unprotected sex, unwanted pregnancies, abortions, having multiple or high-risk partners, raping a partner, and being intoxicated while having sex, alcohol and drug abuse, stealing, violence, and poor performance in school etc. There are many frequently follow romantically driven decisions on sexual relationships like sexually transmitted diseases unwanted pregnancies, abortions, and other related health problems (Hurissa.et.al. 2014). Premarital sexual health behaviour of adolescents in India is a multifaceted and growing problem, influenced by cultural norms, socio-economic factors and transforming social behaviour. The teenage years are a time of great change, both physically and emotionally, and for some young people it will also be a time when they will begin to explore their sexuality. In India, however, there is little discourse about sexual health, and many face stigmas surrounding premarital sexual behavior, which often leaves adolescents without reliable sexual health education. Yet without proper education and resources it can often lead to dangerous activity, unwanted pregnancies and a greater level of STIs which has lasting effects on youth health, education and future opportunities. For effective health promotion among this age group, knowledge of premarital sexual health behaviour among adolescents is crucial to point out the challenges adolescent face and to identify areas where much efforts can be taken to overcome the problems faced by adolescents. This enables policymakers, educators, and health professionals to create culturally appropriate programs effectively teaching adolescents about risk prevention, consent, and healthy relationships. In addition, the promotion of comprehensive sexual education can empower young people to make informed decisions, thus mitigating the health risks arising from the stigma and misinformation. Dealing with adolescent sexual health in a proactive approach with no blame leads to individual well-being, pivotal in promoting public health and social development of the country.On the basis of deeper and critical investigation into the literature, the study found that. This paper will explore and examines the reasons for. It also suggests the immediate action to achieve.
AN INTENSE SURVEY OF WEATHER FORECASTING BASED ON MACHINE LEARNING AND DEEP NEURAL NETWORK
Authors: Awadhiya Deepika , Chandrakar Omprakash , Shameem Bakhtawer
Published: November 2024

The weather forecast determines the future state of the weather. Weather forecasting is very important because both agriculture and business sector rely on weather forecasts. We use artificial neural network and data mining technique to predict weather conditions. Weather is a dynamic process, on-liner artificial neural network (ANN) can operate as process. Our research also pointed out that deep neural network is best methods as compared to traditional algorithms. Main focus is ANN or back propagation methods. Back propagation method is best approach for variation of data as well as long- range weather forecasting. This system will take the parameter and predict weather after analyzing the input information with the information in database. Consequently, two basic functions to be specific classification (training) and prediction (testing) will be performed. The outcomes demonstrated that these data mining procedures can be sufficient for weather forecasting.
Microhabitat of Endangered Species, Lonchura oryzivora in Malang City, Indonesia
Authors: Aryanti Nirmala Ayu , Abdillah Fahmi Maulana , Sari Andini Maya , Pradipta Naresvara Nircela , Yuda Pramana
Published: November 2024

Malang City, located in Java, Indonesia, faces significant anthropogenic pressures but remains an important habitat for the endangered Java sparrow (Lonchura oryzivora). Understanding how Java sparrows adapt to environments with high levels of human activity is essential for their conservation. This study focused on identifying the distribution of Java sparrows and investigating their habitat selection within Malang City. The bird positions were recorded within the tree canopy, and the frequency of canopy use by the birds was determined. Living in the middle of the city impacts the metabolism of birds, as indicated by taking samples and measuring the levels of lead found in their droppings and vegetation used. Encounters near the center of human activity show they can utilize buildings and vegetation they utilize. The Java sparrows predominantly utilize plant parts at the tree level, particularly focusing on the middle canopy part of the edge (TTt) and the middle part (TT). Laboratory tests revealed that the plants utilized by the Java sparrow contain high lead levels. Therefore, to conserve the Java sparrow, it is crucial to improve the quality of their habitat to make it more natural and conduct regular health monitoring to ensure their well-being.
UMA REVISÃO INTEGRATIVA PARA SISTEMAS DE BUSCA POR PATENTES SIMILARES UTILIZANDO IA AVANÇOS, DESAFIOS E APLICAÇÕES
Authors: MARQUES THIAGO DOMINGOS , Gonçalves Alexandre Leopoldo
Published: November 2024

O presente artigo é uma revisão integrativa para sistemas de busca por patentes similares. Com o crescente volume de dados de patentes disponíveis, que são armazenados em escritórios de patentes, tornou-se essencial desenvolver sistemas eficientes para identificação e verificação em documentos de patentes, analisando as suas semelhanças em termos de tecnologia, aplicação ou abordagem. Foram utilizadas diferentes bases para recuperação de artigos que tenham relevância com o tema. Neste sentido, este artigo objetiva examinar os avanços recentes na aplicação de técnicas de Processamento de Linguagem Natural, Aprendizado de Máquina e Mineração de Texto para melhorar a precisão e eficiência na busca por patentes. A partir dos resultados, vislumbra-se que este trabalho seja útil como fonte de consulta aos pesquisadores e profissionais envolvidos na busca e análise de patentes
Laser Oscillation Diameter Variation Effect on Laser Wire Additive Manufacturing Deposition Morphology
Authors:   American Welding Society, YAN CHENXIAO , HAN HONGBIAO , WANG RUI , ZHANG PENG , YANG XIN
Published: November 2024

A high-speed camera was employed to capture the melting process and investigate the impact of laser beam oscillation diameter on weld pool fluctuation and deposition morphology during laser wire additive manufacturing (LWAM) of 316L wire. The transient fluctuations of the weld pool caused by the laser beam were observed at different oscillation diameters. Additionally, 3D morphology measurements were conducted on the deposited layer to assess the effects of different oscillation diameters on its morphology. Further analysis examined the heat dispersion resulting from beam oscillation by plotting the energy distribution for various oscillation diameters. The key findings are as follows: Changes in oscillation diameter resulted in fluctuations within the weld pool that impacted the surface morphology of the deposit and refinement of pore condition as well as alterations in the energy distribution of the weld pool that influenced its contour geometry. Increasing the laser oscillation diameter can effectively make the keyhole shallower, weaken the bottom protrusion of the weld pool, and reduce the curvature of the top surface of the bead. Simultaneously, it can promote the stirring of the liquid solution, effectively refining the porosity area, reducing porosity within the weld pool, and improving the specimen’s density. However, larger oscillation diameters lead to more-significant hump arch formation on the deposited surface and larger roughness values.
SVCT2 y sus efectos en la arborización dendrítica de motoneuronas humanas; un modelo de Esclerosis Lateral Amiotrófica (ELA) in vitro.
Authors:   , SMITH GHIGLIOTTO JAVIERA FERNANDA
Published: November 2024

La Esclerosis Lateral Amiotrófica (ELA) es una enfermedad neurodegenerativa multifactorial caracterizada principalmente por la pérdida selectiva y progresiva de motoneuronas (MNs). Los pacientes rara vez sobreviven más de 5 años luego de la aparición de los síntomas, debido a que el conocimiento limitado de sus causas subyacentes ha dificultado el desarrollo de terapias con efectos más significativos que los modestamente desarrollados hasta ahora.
La primera mutación descubierta causante de ELA se encuentra en el gen que codifica la Superóxido Dismutasa de Cobre y Zinc 1 (SOD1), una enzima antioxidante que cataliza la dismutación del anión superóxido en oxígeno y peróxido de hidrógeno, cuyas mutaciones se convierten en la segunda causa más frecuente de la enfermedad.
En específico, la mutación SOD1G93A, el modelo más utilizado en el estudio de la enfermedad provoca en un primer momento, estrés oxidativo y reducciones en la arborización dendrítica y axonal, seguido de hiperexcitabilidad, denervación y finalmente la muerte de MNs.
En el desafío de buscar moléculas neuroprotectoras en el contexto de ELA, investigaciones anteriores han asociado a deficiencias en los niveles de vitamina C (VC), con un alto riesgo en la obtención de la enfermedad, lo que podría explicarse principalmente por sus propiedades antioxidantes, así como por el fortalecimiento que el ácido ascórbico (AA), la forma reducida de la VC y su transportador cerebral, SVCT2 provocan en la viabilidad celular y en la diferenciación y maduración de distintas células neuronales, demostrando así, sus efectos neuroprotectores.
Por lo tanto, nuestra hipótesis de trabajo se basó en que la sobreexpresión de SVCT2 promueve la recuperación de la arborización dendrítica luego del daño celular inducido por la mutación SOD1G93A en un modelo in vitro de ELA en MNs espinales humanas generadas desde células madre pluripotentes inducidas (iPSCs).
En este contexto, se demostró que la sobreexpresión de SVCT2 en neuronas enfermas, recuperó el 63,9% y el 105% de la red dendrítica y axonal, respectivamente, redes que, fueron gravemente disminuidas por la mutación SOD1G93A.
Por otra parte, en MNs la mutación causó pérdidas en la expresión de la tinción de la proteína presináptica piccolo y aumentos en la inmunofluorescencia de PSD95, probablemente fortaleciendo la excitotoxicidad. Mientras que al sobreexpresar SVCT2, las células recuperaron parcialmente los niveles de piccolo y disminuyeron la tinción de PSD95, probablemente reduciendo a su vez la excitotoxicidad.
Los efectos morfológicos y a nivel de proteínas sinápticas provocados por la mutación SOD1G93A en nuestras MNs humanas representan temporalmente a la etapa presintomática de la enfermedad.
Finalmente, la sobreexpresión de SVCT2 fortaleció la maduración morfológica de MNs sanas y recuperó la red dendrítica y axonal, previamente degenerada por la expresión de SOD1G93A en MNs humanas.
Phrasal verbs in High School students’ L2 English writing: A language learner corpus study
Authors:   , SUÁREZ DELUCCHI BEATRIZ VALENTINA
Published: November 2024

El uso de los verbos fraseológicos (VFs) refleja un nivel avanzado de dominio del idioma. Debido a sus múltiples significados y funciones, el uso de éstos es esencial para lograr precisión en inglés. Su carácter polisémico y su manera de aparecer en ciertas composiciones o discursos contribuyen a una mayor naturalidad y fluidez en el habla. El presente estudio posee un enfoque léxico, que se centra en la importancia del vocabulario en el aprendizaje de idiomas. El análisis de VFs puede integrarse en este enfoque, considerando cómo las unidades léxicas contribuyen a la competencia comunicativa de los aprendientes. Basándonos en la lista de los VFs más frecuentes conocida como PHaVE List, analizamos el uso éstos en las composiciones escritas de 148 estudiantes, hombres y mujeres, de primero y segundo año de enseñanza media de un colegio de inmersión ubicado en Concepción, Chile. El objetivo fue determinar en qué medida se utilizan los verbos fraseológicos en las composiciones escritas de estudiantes bilingües de enseñanza media, según su edad, sexo y nivel escolar, como parte de lo que implica usar el lenguaje de la forma más natural posible al comunicarse en un segundo idioma. Se realizó un análisis de corpus a través de dos programas, Sketch Engine y ADELEX Analyser, y un análisis manual adicional, para examinar las variables mencionadas anteriormente. A la luz de los resultados, se observó que, dentro de este corpus de aprendiente, las estudiantes mujeres utilizaron un mayor número de verbos fraseológicos (p=0.026). Considerando el tema limitado a las ventajas y desventajas de estudiar desde la casa en pandemia.
Acción intersectorial: estrategia de intervención en respuesta a la violencia en las relaciones íntimas.
Authors:   , VALENZUELA FUENTES LISSETTE ELIZABETH
Published: November 2024

El presente estudio se enmarcó en los procesos de acción intersectorial (AI) en materia de violencia en las relaciones íntimas (VRI), siendo su objetivo general, conocer los procesos de acción intersectorial en respuesta a la problemática de VRI en la comuna de Talcahuano.
El marco teórico se construyó en base a la Teoría del Actor Red, también conocida como Teoría de la Traducción. La metodología fue de carácter cualitativa, utilizando dos métodos de recolección de información, entrevista semiestructura y grupo de discusión.
Los resultados dan cuenta de la participación de actores y actrices de diversos sectores. A través de la Red por la No Violencia de Talcahuano, fue posible conocer sus roles, liderazgo, la manera de problematizar la VRI, los niveles de acción intersectorial presentes, la evolución e historia de esta red, estrategias, factores facilitadores y obstaculizadores de la AI en el abordaje de la VRI.
Los principales hallazgos dan cuenta que La Red por la No Violencia está compuesta por una diversidad de actores locales del sector público y privado, con una amplia experiencia de trabajo colaborativo de más de 25 años. En sus inicios, la red mantenía un funcionamiento autónomo, un liderazgo democrático, alta participación de organizaciones sociales. En la actualidad, el funcionamiento es instrumental, alta presencia de organismos estatales y municipales, un liderazgo definido, movilización de recursos, rotación y desplazamiento de actores lo que podría generar una pérdida de memoria colectiva de esta mesa. La red demuestra elementos facilitadores como el compromiso, motivación, interés, vínculo entre profesionales y usuarias(os) y obstaculizadores como el desconocimiento y desactualización de las dinámicas intersectoriales, desconocimiento de protocolos y falta de recursos.