bluuebunny/crossref_metadata_2025 huggingface dataset:
Nanomaterials as Ultrasound Theragnostic Tools for Heart Disease Treatment/Diagnosis
Authors: Alphandéry Edouard
Published: February 2022

A variety of different nanomaterials (NMs) such as microbubbles (MBs), nanobubbles (NBs), nanodroplets (NDs), and silica hollow meso-structures have been tested as ultrasound contrast agents for the detection of heart diseases. The inner part of these NMs is made gaseous to yield an ultrasound contrast, which arises from the difference in acoustic impedance between the interior and exterior of such a structure. Furthermore, to specifically achieve a contrast in the diseased heart region (DHR), NMs can be designed to target this region in essentially three different ways (i.e., passively when NMs are small enough to diffuse through the holes of the vessels supplying the DHR, actively by being associated with a ligand that recognizes a receptor of the DHR, or magnetically by applying a magnetic field orientated in the direction of the DHR on a NM responding to such stimulus). The localization and resolution of ultrasound imaging can be further improved by applying ultrasounds in the DHR, by increasing the ultrasound frequency, or by using harmonic, sub-harmonic, or super-resolution imaging. Local imaging can be achieved with other non-gaseous NMs of metallic composition (i.e., essentially made of Au) by using photoacoustic imaging, thus widening the range of NMs usable for cardiac applications. These contrast agents may also have a therapeutic efficacy by carrying/activating/releasing a heart disease drug, by triggering ultrasound targeted microbubble destruction or enhanced cavitation in the DHR, for example, resulting in thrombolysis or helping to prevent heart transplant rejection.
Potential of Biofermentative Unsulfated Chondroitin and Hyaluronic Acid in Dermal Repair
Authors: D’Agostino Antonella , La Gatta Annalisa , Stellavato Antonietta , Cimini Donatella , Corsuto Luisana , Cammarota Marcella , D’Agostino Maria , Schiraldi Chiara
Published: February 2022

Chondroitin obtained through biotechnological processes (BC) shares similarities with both chondroitin sulfate (CS), due to the dimeric repetitive unit, and hyaluronic acid (HA), as it is unsulfated. In the framework of this experimental research, formulations containing BC with an average molecular size of about 35 KDa and high molecular weight HA (HHA) were characterized with respect to their rheological behavior, stability to enzymatic hydrolysis and they were evaluated in different skin damage models. The rheological characterization of the HHA/BC formulation revealed a G’ of 92 ± 3 Pa and a G″ of 116 ± 5 Pa and supported an easy injectability even at a concentration of 40 mg/mL. HA/BC preserved the HHA fraction better than HHA alone. BTH was active on BC alone only at high concentration. Assays on scratched keratinocytes (HaCaT) monolayers showed that all the glycosaminoglycan formulations accelerated cell migration, with HA/BC fastening healing 2-fold compared to the control. In addition, in 2D HaCaT cultures, as well as in a 3D skin tissue model HHA/BC efficiently modulated mRNA and protein levels of different types of collagens and elastin remarking a functional tissue physiology. Finally, immortalized human fibroblasts were challenged with TNF-α to obtain an in vitro model of inflammation. Upon HHA/BC addition, secreted IL-6 level was lower and efficient ECM biosynthesis was re-established. Finally, co-cultures of HaCaT and melanocytes were established, showing the ability of HHA/BC to modulate melanin release, suggesting a possible effect of this specific formulation on the reduction of stretch marks. Overall, besides demonstrating the safety of BC, the present study highlights the potential beneficial effect of HHA/BC formulation in different damage dermal models.
Model of Genetic Code Structure Evolution under Various Types of Codon Reading
Authors: Błażej Paweł , Pawlak Konrad , Mackiewicz Dorota , Mackiewicz Paweł
Published: February 2022

The standard genetic code (SGC) is a set of rules according to which 64 codons are assigned to 20 canonical amino acids and stop coding signal. As a consequence, the SGC is redundant because there is a greater number of codons than the number of encoded labels. This redundancy implies the existence of codons that encode the same genetic information. The size and organization of such synonymous codon blocks are important characteristics of the SGC structure whose evolution is still unclear. Therefore, we studied possible evolutionary mechanisms of the codon block structure. We conducted computer simulations assuming that coding systems at early stages of the SGC evolution were sets of ambiguous codon assignments with high entropy. We included three types of reading systems characterized by different inaccuracy and pattern of codon recognition. In contrast to the previous study, we allowed for evolution of the reading systems and their competition. The simulations performed under minimization of translational errors and reduction of coding ambiguity produced the coding system resistant to these errors. The reading system similar to that present in the SGC dominated the others very quickly. The survived system was also characterized by low entropy and possessed properties similar to that in the SGC. Our simulation show that the unambiguous SGC could emerged from a code with a lower level of ambiguity and the number of tRNAs increased during the evolution.
Adipose-Derived Stem Cells from Type 2 Diabetic Rats Retain Positive Effects in a Rat Model of Erectile Dysfunction
Authors: Quaade Marlene Louise , Dhumale Pratibha , Steffensen Simon Gabriel Comerma , Beck Hans Christian , Harvald Eva Bang , Jensen Charlotte Harken , Lund Lars , Andersen Ditte Caroline , Sheikh Søren Paludan
Published: February 2022

Erectile dysfunction is a common complication associated with type 2 diabetes mellitus (T2DM) and after prostatectomy in relation to cancer. The regenerative effect of cultured adipose-derived stem cells (ASCs) for ED therapy has been documented in multiple preclinical trials as well as in recent Pase 1 trials in humans. However, some studies indicate that diabetes negatively affects the mesenchymal stem cell pool, implying that ASCs from T2DM patients could have impaired regenerative capacity. Here, we directly compared ASCs from age-matched diabetic Goto–Kakizaki (ASCGK) and non-diabetic wild type rats (ASCWT) with regard to their phenotypes, proteomes and ability to rescue ED in normal rats. Despite ASCGK exhibiting a slightly lower proliferation rate, ASCGK and ASCWT proteomes were more or less identical, and after injections to corpus cavernosum they were equally efficient in restoring erectile function in a rat ED model entailing bilateral nerve crush injury. Moreover, molecular analysis of the corpus cavernosum tissue revealed that both ASCGK and ASCWT treated rats had increased induction of genes involved in recovering endothelial function. Thus, our finding argues that T2DM does not appear to be a limiting factor for autologous adipose stem cell therapy when correcting for ED.
Lauric Acid Induces Apoptosis of Rice Sheath Blight Disease Caused by Rhizoctonia solani by Affecting Fungal Fatty Acid Metabolism and Destroying the Dynamic Equilibrium of Reactive Oxygen Species
Authors: Wang Jian , Yang Chenglong , Hu Xianfeng , Yao Xiaolong , Han Lei , Wu Xiaomao , Li Rongyu , Wen Tingchi , Ming Li
Published: February 2022

Rice sheath blight, caused by Rhizoctonia solani, is one of the major rice diseases. In order to better understand the inhibitory mechanism of lauric acid on the disease, RNA sequencing (RNA-Seq) was used to analyze the transcriptome changes in Rhizoctonia solani treated with lauric acid for 3 h, 6 h, 18 h, and 24 h, including 2306 genes; 1994 genes; 2778 genes; and 2872 genes. Based on gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, we found that protein processing in endoplasmic reticulum (KO04141), carbon metabolism (KO01200), and starch and sucrose metabolism were significantly enriched. Most oxidoreductase, dehydrogenase, reductase, and transferase genes are downregulated in this process. Lauric acid can affect ergosterol content, mitochondrial membrane potential collapse, hydrogen peroxide content, electrolyte leakage, reactive oxygen species balance, and can induce endoplasmic reticulum (ER) stress. Lauric acid also increased the expression levels of ER chaperone glucose regulatory protein Grp78 (BIP), protein disulfide isomerase (PDI), and Calpain (CNX), and decreased the expression levels of HSP40, HSP70, and HSP90 genes. Lauric acid affected the ergosterol content in the cell membrane of R. solani, which induces ER stress and increases the BiP level to induce the apoptosis of Rhizoctonia solani. These results indicated that lauric acid could be used to control rice sheath blight.
Analysis of the application of various numerical integration methods and their practical implementation in MATLAB CAD
Authors:   Bauman Moscow State Technical University, Moscow, Yudachev S.S. , Sitnikov S.S. ,   Bauman Moscow State Technical University, Moscow, Gordienko N.A. ,   Bauman Moscow State Technical University, Moscow, Monakhov P.A. ,   Monakhov P.A.
Published: February 2022

The article presents an analysis of numerical integration methods. These methods are frequently used in solving various technical problems in production. Iterative numerical methods in MATLAB CAD are considered and implemented, including the method of integration by central rectangles, the trapezoidal method, and Simpson’s rule. The practical significance of the work is familiarization with basic numerical methods that are widely used in computing, as well as with a powerful computing tool – MATLAB. In the course of the work, the algorithms of each method are described, program codes with illustrations for evaluating the results of calculating by a particular method are given. The conclusions are drawn regarding the accuracy of each method. The software and mathematical excerpts used in the work are publicly available on the Internet, which allows anyone to carry out similar work and make sure that the written codes and the obtained conclusions are correct. This work can be used not only to train students in the field of electronic device development in terms of their algorithmization and for the organization of laboratory work, but also in the creation and design of real devices both in production and within a higher educational institution, for example, for the development of laboratory work using specialized CAD. Familiarization and study of this software are conducted at the departments of one of the leading engineering universities of the Russian Federation.
Fault identification using a structural and functional approach for digitalization conditions
Authors:   Donetsk National Technical University, Donetsk, Sidorov V.A. , Sidorov A.V. ,   Donetsk National Technical University, Donetsk, Oshovskaya E.V. ,   Donetsk National Technical University, Donetsk, Shamray Yu.A. ,   Donetsk National Technical University, Donetsk
Published: February 2022

One of the fundamental components in equipment maintenance and repair systems that implement modern risk-oriented strategies is information. The effectiveness of taken decisions is determined not only by the volume, but also by the quality of information data. The article formulates and justifies the requirements for the collected information on the technical condition of equipment and data for the analysis of its failures, taking into account modern capabilities and conditions of universal digitalization. The role of mathematical modeling in the formation of data on the functional parameters of the machine is shown, the main stages of construction are outlined and a set of developed mathematical models of the refrigerator is presented. Methods of equipment fault analysis are considered, their characteristics are given, areas and application features are indicated. An algorithm for analyzing events related to the operability of equipment based on entries in the equipment maintenance log is described. The proposed approaches are demonstrated by the example of a refrigerator with walking beams and a hydraulic drive, which is an integral part of the technological line of the CCM and has the most characteristic features of metallurgical equipment, which allows to use the solution of the problem of collecting and processing information about the technical condition of the CCM refrigerator as a standard.
Influence of polyunsaturated fatty acids of feed on metabolic parameters in herd horses of Yakutia
Authors:   Yakut Scientific Research Institute of Agriculture named after M. G. Safronov – a separate subdivision Federal State Budgetary Institution of Science Federal Research Center “Yakut Scientific Center of the Siberian Branch of the Russian Academy of Science”, Republic of Sakha (Yakutia), Yakutsk, Ivanov R. V. , Pak M. N. ,   Yakut Scientific Research Institute of Agriculture named after M. G. Safronov – a separate subdivision Federal State Budgetary Institution of Science Federal Research Center “Yakut Scientific Center of the Siberian Branch of the Russian Academy of Science”, Republic of Sakha (Yakutia), Yakutsk
Published: February 2022

The research of lipid metabolism is especially relevant for the breeds of herd horses in Yakutia, because the energy balance of their body under extreme conditions of the region in winter largely depends on the fat reserves in the body of animals and the efficiency of lipid assimilation in the body of horses, mainly from plant feed. Therefore, the study of the lipid composition of pasture feed of herd horses in Yakutia depending on the seasons of the year, their digestibility in the body of horses, the effect of the lipid composition of feed on the chemical composition of horse meat is very relevant. The purpose of the work was to investigate the effect of polyunsaturated fatty acids of feed on metabolic parameters in breeds of herd horses in Yakutia and to develop the technology for obtaining a concentrate with polyunsaturated fatty acids from the internal fat of foals. The object of research were: 1) samples of pasture grasses from horsetail and horsetail-free vegetation of the pastures in the Verkhoyansky area; 2) winter-green mass of oats and afterfeed of natural grass; 3) samples of flax press-cake; 4) samples of adipose tissue of young Yakut horses aged 6 months and adult horses; 5) meat samples of meat of types of Yakut breed such as Kolymsky, Yansky and Korennoy and horses of Megezheskaya breed; 6) horses of Yakut breed in OOO “Khoroobut” in the Megino-Kangalassky area, OOO “Sartansky” in the Verkhoyansky area. It has been found by studies that the consumption of dry matter of feed during the breeding of horses on the winter-green mass of oats was 31,3 % significantly higher than during the breeding on the afterfeed of natural grass and amounted to 14,7±0,30 kg (P ≥ 0,95). Differences were also found in the content of metabolic energy in 1 kg of dry matter of consumed feed. Thus, the content of metabolic energy in the winter grazing from the winter-green mass of oats was 16,2 % higher (9,9±0,04 MJ) than in the natural herbage (8,3±0,23 MJ), the difference was statistically significant (P ≥ 0,95). The internal fat of Yakut horses can serve as a highly valuable raw material as a source of polyunsaturated fatty acids for the production of functional food products.
Primary care workforce composition and population, professional, and system outcomes: a retrospective cross-sectional analysis
Authors: Gibson Jon , Francetic Igor , Spooner Sharon , Checkland Kath , Sutton Matt
Published: February 2022

Background

The diversification of types of staff delivering primary care may affect professional, population, and system outcomes.

Aim

To estimate associations between workforce composition and outcomes.

Design and setting

Cross-sectional analysis of 6210 GP practices from a range of geographical settings across England in 2019.

Method

A multivariable regression analysis was undertaken, relating numbers of staff in four groups — GPs, nurses, healthcare professionals, and health associate professionals — to patient access and satisfaction, quality of clinical care and prescribing, use of hospital services, GP working conditions (subsample of practices), and costs to the NHS. Data were obtained from the GP Patient Survey 2019, Quality and Outcomes Framework, prescribing data, the Hospital Episode Statistics database, the NHS Payments to General Practice 2019/2020, and the Tenth National GP Worklife Survey 2019.

Results

Having additional GPs was associated with higher levels of satisfaction for the GPs themselves and for patients, whereas additional staff of other types had opposite associations with these outcomes. Having additional nurses and health associate professionals was associated with lower costs per prescription but more prescribing activity than having additional staff from the other two groups. Having more GPs was associated with higher costs per prescription and lower use of narrow-spectrum antibiotics compared with the other staff groups. Except for health associate professionals, greater staff numbers were associated with more hospital activity.

Conclusion

Professional, population, and system outcomes showed a variety of associations with primary care workforce composition. Having additional nurses was associated with lower quality in some aspects, and higher costs and activity. The association between additional healthcare professionals or health associate professionals and higher costs was less than that for additional GPs, but was also linked to lower patient and GP satisfaction.
Metodologia G5 Ambiental aplicada em escolas municipais
Authors: Silva Rogério Ferreira da , Borba Bruno Ferreira da Costa , Silva Gilson Lima da
Published: February 2022

A Educação Ambiental tem sido implementada como uma alternativa para minimizar as atividades humanas que afetam direta ou indiretamente a saúde, a segurança ou o bem-estar das pessoas, bem como os impactos na qualidade dos recursos naturais. Nesse contexto, foi implantado em escolas da cidade de Caruaru (PE) com o objetivo de formar agentes ambientais que pudessem atuar na escola e no entorno. A metodologia utilizada no trabalho, denominada G5 Ambiental, consistiu em cinco eixos, gestão de água, gestão de energia, gestão de resíduos sólidos, gestão de fauna e flora e gestão do conhecimento. As ferramentas utilizadas para implantação da metodologia foram: palestras, vídeos, oficinas de reciclagem e visitas técnicas. Os alunos foram motivados a transformar o ambiente escolar, a partir da recuperação e adaptação de um espaço que possibilitasse a prática de ações de Educação Ambiental. Portanto, a metodologia G5-Ambiental, permitiu a participação direta e indireta da comunidade em ações que transformaram o ambiente escolar, contribuindo para a sua sustentabilidade.
Sistemas de Indicadores de Sustentabilidade Empresarial para o setor sucroenergético fomentados em Programas de Pós-Graduação
Authors: Moreira Josicleide de Amorim Pereira , Lima Eduardo Rodrigues Viana de , Souza Bruno César Bezerra Nóbrega de
Published: February 2022

O objetivo desta pesquisa é identificar os sistemas de indicadores de sustentabilidade empresarial direcionados ao setor sucroenergético. Como objeto de análise, optaram-se pelas produções científicas desenvolvidas no Brasil e disponibilizadas no portal da Biblioteca Digital Brasileira de Teses e Dissertações. Para tanto, considerou-se a Análise de Redes Sociais, adotando-se o grau de centralidade entre os atores da rede social analisada. Os principais resultados foram os seguintes: insuficiência de produções científicas que contemplem, minimamente, as dimensões de sustentabilidade econômica, social e ambiental; produção média de 1,2 trabalhos por ano, entre 2000 e 2019, sem abranger todos os setores econômicos; e um único trabalho direcionado ao setor sucroenergético.
Proposta de Jogo Educativo para Educação Ambiental no Ensino Básico
Authors: Laércio Francisco Giovani Souza , Fonseca Leticia Rodrigues
Published: February 2022

Propor uma ferramenta pedagógica para a Educação Ambiental (EA) no Ensino Básico foi o objetivo do presente estudo. Para isso, desenvolveu-se um jogo educativo digital no formato de um quiz, submetido para o uso de alunos do Ensino Fundamental II de uma Instituição de Educação Básica Pública do Estado de São Paulo. Após a aplicação do jogo em duas etapas, evidenciou-se uma melhoria no desempenho dos alunos, pois por meio da avaliação dos erros e acertos foi possível aprender, principalmente, quando o jogo e o professor apresentavam as justificativas para as questões incorretas e corretas. Constatou-se que os alunos visualizam os jogos como ferramentas que promovem a aprendizagem significativa e ativa.
Interdisciplinaridade e Educação Ambiental: um olhar sobre o declínio das abelhas
Authors: Silva Crisilandia de Nave , Feistel Roseli Adriana Blümke , Wobeto Carmen , Pinheiro Jean Reinildes
Published: February 2022

O estudo apresenta uma análise de resultados de dissertações e artigos científicos, publicados em Bases de Dados das áreas de ensino de Ciências e Biomedicina no período de 2016 a 2020, acerca de pesquisas relacionadas ao ensino das radiações eletromagnéticas numa abordagem interdisciplinar. Em paralelo à investigação, buscou-se, ainda, trabalhos que discutiram a interação entre a radiação produzida pelos celulares, as estações de rádio base e as abelhas com vistas a compor uma transposição didática interdisciplinar, relacionando conceitos de eletromagnetismo e de Biologia. Trata-se de uma pesquisa de revisão de literatura, de natureza qualitativa e do tipo bibliográfico. Diante do estudo realizado, foi possível identificar que a abordagem da perspectiva interdisciplinar no ensino do Eletromagnetismo vem sendo pouco explorado no processo de ensino-aprendizagem de Física.
As funções da Educação Ambiental na efetividade de políticas ambientais marinhas e costeiras no Brasil
Authors: Matias Tális Pereira , Imperador Adriana Maria
Published: February 2022

Ecossistemas marinhos e ambientes costeiros são amparados por leis específicas que demandam ações complementares como fiscalização e Educação Ambiental para a efetividade de muitos aspectos abordados por estas bases jurídicas. Desta forma, este trabalho objetiva a avaliação das funções e proposições de alternativas de Educação Ambiental para a eficácia de Políticas Ambientais Marinhas e Costeiras (PAMC). A metodologia utilizada foi qualitativa, buscando informações em decretos, leis e artigos científicos. Dentre os principais resultados destaca-se o potencial e funções da Educação Ambiental para a conquista de objetivos conservacionistas e sustentáveis associados às PAMC no Brasil.
Educação Ambiental: um relato de experiência na Comunidade Indígena assuriní, município de Tucuruí (PA)
Authors: Louzada Aline Furtado , Silva Danubya dos Santos , Souza Raiane Contente de , Silva Wendrya Gabriela Alves da
Published: February 2022

O objetivo desta pesquisa é relatar as experiências vivenciadas nas ações de resíduos sólidos realizadas pelo Grupo de Estudos em Educação Ambiental (GEA-CAMTUC), projeto de extensão da Universidade Federal do Pará, Campus Tucuruí, na comunidade indígena Assuriní do Trocará, no ano de 2019. O estudo evidenciou que a Educação Ambiental no ensino não formal atrelada aos saberes ambientais indígenas é fundamental para a mitigação de impactos relacionados à saúde e ao saneamento básico, aos quais o povo Assuriní tem sido submetido durante seus processos de deslocamentos.
PENGARUH MODEL BERBASIS PjBL BERBANTUAN MEDIA AUDIO VISUAL TERHADAP KETERAMPILAN MEMPRODUKSI TEKS EKSPLANASI
Authors:   STKIP YDB Lubuk Alung, Febrimora Hendri Bunga
Published: February 2022

This study I am as to :1) descript the skills of producing explanatory text with PjBL assisted be audio visual media. 2) descript the skill to producing explanatory the text after the aplication of the PjBL model assisted by audio visual media. 3) analyzing the effect of the application of the PjBL model assisted by audio visual media on the skills of producing explanatory text. This type of research is a quantitative study using descriptive analytical methods with a pre test and posttest one group design.Population in this study were grade VIII students of SMPN 15 Padang registered in 2019, totaling 117 students. The sample of this study were studentsin grade VIII totalling 30 students and the sampling in this study wash using purposive sampling technique. Result and discussion : 1) the skill of producing explanatory text before applying the PjBL model assisted by audiovisual media is in the range of values of 51,57 with almost sufficient qualifications. 2) the skill of producing explanatory text after the application of the PjBL model assisted by audiovisual media is in the range of values 81,13 with good qualifications. 3) based on the result of hypothesis testing, it can be concluded that there is an effect of the skill of producing explanatory text for grade VIII students of SMP N 15 Padangbefore and after the application of the PjBL model assisted by audio visual media at a significant level of 0.95 with degrees of freedom n-1 (30-1=29).
Dielectric Manipulated Charge Dynamics in Contact Electrification
Authors: Shi Kunming , Chai Bin , Zou Haiyang , Min Daomin , Li Shengtao , Jiang Pingkai , Huang Xingyi
Published: February 2022

Surface charge density has been demonstrated to be significantly impacted by the dielectric properties of tribomaterials. However, the ambiguous physical mechanism of dielectric manipulated charge behavior still restricts the construction of high-performance tribomaterials. Here, using the atomic force microscopy and Kelvin probe force microscopy, an in situ method was conducted to investigate the contact electrification and charge dynamics on a typical tribomaterial (i.e., BaTiO
3
/PVDF-TrFE nanocomposite) at nanoscale. Combined with the characterization of triboelectric device at macroscale, it is found that the number of transferred electrons increases with contact force/area and tends to reach saturation under increased friction cycles. The incorporated high permittivity BaTiO
3
nanoparticles enhance the capacitance and electron trapping capability of the nanocomposites, efficiently inhibiting the lateral diffusion of electrons and improving the output performance of the triboelectric devices. Exponential decay of the surface potential is observed over monitoring time for all dielectric samples. At high BaTiO
3
loadings, more electrons can drift into the bulk and combine with the induced charges on the back electrode, forming a large leakage current and accordingly accelerating the electron dissipation. Hence, the charge trapping/storing and dissipating, as well as the charge attracting properties, should be comprehensively considered in the design of high-performance tribomaterials.
Hubungan Efikasi Diri dan Dukungan Sosial dengan Motivasi Berprestasi Siswa dalam Pembelajaran Daring Dampak Pandemi Covid-19
Authors: Nurjannah Laely , Purwadi  , Yuzarion
Published: February 2022

Penelitian ini bertujuan untuk melihat hubungan antara efikasi diri dan dukungan sosial dengan motivasi berprestasi siswa dalam pembelajaran daring dampak pandemi covid-19. Responden pada penelitian ini adalah siswa kelas IX SMP Muhammadiyah 1 Gombong. Dengan menggunakan teknik pengambilan sampel cluster random sampling. Pengumpulan data pada penelitian ini menggunakan 3 alat ukur yaitu alat ukur motivasi berprestasi, efikasi diri dan dukungan sosial. Analisis data menggunakan analisis regresi linier berganda. Hasil analisis pada penelitian ini adalah R sebesar 0,770 dengan taraf signifikasi (p<0,01) artinya terdapat hubungan positif yang sangat signifikan antara efikasi diri dan dukungan sosial dengan motivasi berprestasi. Berdasarkan uji hipotesis, kesimpulan penelitian ini adalah ada hubungan yang signifikan antara efikasi diri dan dukungan sosial dengan motivasi berprestasi.
Start up Paper Soap Business Based on Katuk Leaf (Sauropus androgyrus (l) merr) by Students in Mandala Waluya University
Authors: Nurdin Muhammad , Watoni Haris , Khaeruni Andi , Maulidiyah Maulidiyah , Arham Zul , Irwan Irwan , Salim La Ode Agus
Published: February 2022

Bahan anti jamur busuk buah kakao berbasis suspensi TiO2 telah disosialisasikan dan diaplikasikan pada lahan perkebunan kakao Kelompok Tani Mekohia, desa Lebo Jaya-Konawe Selatan. Sosialisasi dan aplikasi bahan anti jamur dilakukan melalui program pengabdian berbasis masyarakat. Pemilihan kelompok tani Mekohia sebagai mitra didasarkan pada fakta bahwa kelompok ini mengalami kesulitan dalam penanganan penyakit busuk buah kakao. Selain melakukan pembinaan berupa bimbingan teknologi, kegiatan ini juga bertujuan mengenalkan dan menerapkan sebuah produk teknologi baru dalam pencegahan dan penanganan penyakit busuk buah kakao yang disebabkan oleh jamur Phytopthora palmivora (P. palmivora). Metode kegiatan terdiri dari tiga tahapan penting, meliputi (i) focus group discussion (FGD), (ii) tahap pembimbingan teknis pembuatan suspensi TiO2 dan cara penggunaannya, dan (iii) penguatan konsep pengendalian hama dan penyakit tanaman kakao. Kegiatan ini menghasilkan produk bahan anti jamur busuk buah kakao berbasis suspensi TiO2 yang diaplikasikan secara langsung pada lahan perkebunan kakao mitra. Luaran lainnya berupa kemampuan kelompok tani Mekohia dalam penyiapan suspensi TiO2 secara mandiri. Indikator keberhasilan kegiatan diamati dari tingkat keseriusan mitra dalam berdialog dan kemampuan mitra dalam menerapkan suspensi TiO2. Akhir kegiatan ini menghasilkan Memorandum of Understanding (MoU) antara tim pengabdi dengan mitra Mekohia tentang penggunaan bahan anti jamur suspensi TiO2 secara berkala.
Education of Natural Immunomodulator Based on TOGA in Abeli District, Kendari City
Authors: Sahidin Sahidin , Fristiohady Adryan , Malaka Muhammad Hajrul , Ihsan Sunandar , Pascayantri Asniar , Astiasal Nurkhalis Bintang , Ramadhan Muhammad
Published: February 2022

Indonesia merupakan negara dengan biodiversitas yang tinggi sehingga kaya akan berbagai tanaman obat yang sangat potensial untuk dikembangkan namun belum dikelola dan dimanfaatkan secara optimal. Tanaman obat dapat meningkatkan kekebalan tubuh, karena bersifat pencegahan (preventif) dan promotif melalui kandungan metabolit sekunder contohnya seperti gingiro pada jahe dan santoriso pada temulawak yang mampu meningkatkan system kekebalan tubuh. Sosialisasi penggunaan tanaman obat keluarga untuk mewujudkan masyarakat sehat di Kelurahan Abeli ini bertujuan untuk meningkatkan system kekebalan tubuh dan imunitas m asyarakat kelurahan Abeli. Kegiatan ini memiliki tahapan persiapan dan pelaksanaan. Persiapan dilakukan dengan mempersiapkan lahan dan bibit dari tanaman obat keluarga (TOGA). Tahapan pelaksanaan dilakukan dengan melakukan Penanaman TOGA dan memberikan pengetahuan melalui sosialisasi kepada masyarakat dan mahasiswa. Kegiatan pengabdian masyarakat ini diharapkan mampu meningkatkan imunitas tubuh dan dapat mencegah penyebaran COVID-19.
Análisis de los hábitos de estudio en una muestra de alumnos universitarios
Authors:   , Beti María Mónica
Published: February 2022

En este trabajo de investigación orientado a la finalización de la Maestría en Educación Odontológica, proponemos reconstruir los hábitos de estudio de estudiantes universitarios de las carreras de Sociología y de Trabajo Social. En este sentido, buscaremos analizar las experiencias en sí mismas a la vez que planteamos un estudio comparativo de dos disposiciones diferentes para el pasaje por la universidad. Entendemos entonces que el recorrido para nuestros objetivos se basa en descubrir cuáles son las estrategias de estudio de estudiantes avanzados/as a su vez que en el caso de estudiantes ingresantes. Para ello, indagaremos sobre los métodos y técnicas que emplean para estudiar, en la organización de los tiempos y en los vínculos que se desprenden entre estudiantes, docentes y la Universidad en general. En este sentido, buscamos acercarnos a las experiencias de estudio de los/as estudiantes para poder pensar y problematizar el rol pedagógico de los/as docentes en contextos donde los paradigmas de enseñanza y aprendizaje se ven constantemente desafiados. Para ello, hemos realizado 50 encuestas a cada una de las facultades, y hemos acudido a fuentes secundarias como los planes de estudio de dichas carreras y charlas informales con los/as estudiantes para comprender, complejizar y afirmar aquello que se evalúa en las encuestas.
Presença de Peptostreptococcus indolicus em bula timpânica de cão com otite média
Authors: Leite Carlos Artur Lopes
Published: February 2022

A otite média é definida como uma inflamação da orelha média. Em cães, essa condição é uma das causas mais comuns na manutenção de otite externa recorrente. Tanto bactérias aeróbicas como anaeróbicas estão presentes na bula timpânica doente, sendo que em algumas circunstâncias, torna-se difícil determinar qual o papel que estes microrganismos ali exercem. Apesar de a microbiota aeróbica ser frequentemente estudada em cães com otopatias, poucos dados estão disponíveis sobre os microrganismos anaeróbicos estritos presentes nas orelhas destes pacientes. Neste relato é revelado o isolamento da bactéria anaeróbica Peptostreptococcus indolicus no exsudato de um cão adulto da raça São Bernardo com otite média crônica bilateral, se tratando da primeira descrição na literatura veterinária relacionada à presença desta espécie bacteriana em otite média canina. Com base neste achado, é sugerido que bactérias anaeróbicas como P. indolicus podem estar relacionadas ao processo infeccioso da orelha média em cães.
Pengelolaan Dokumen Kepangkatan Dosen Berbasis Komputasi Awan pada Perguruan Tinggi Keagamaan Islam Negeri
Authors: Mafar Fiqru
Published: February 2022

Artikel ini membahas tentang pemanfaatan OneDrive sebagai sarana penyimpanan di dunia maya dalam pengelolaan dokumen kepangkatan dosen di sebuah Perguruan Tinggi Keagamaan Islam Negeri (PTKIN) Jawa Timur. Tujuan penelitian ini adalah untuk menggambarkan bagaimana penerapan pengelolaan dokumen kepangakatan dosen sebuah PTKIN Jawa Timur menggunakan OneDrive. Metode penelitian yang digunakan adalah metode kualitatif. Pengumpulan data dalam penelitian ini dilakukan melalui proses wawancara dan dokumentasi. Hasil pengumpulan data tersebut kemudian dianalisis secara induktif. Data hasil penelitian ditampilkan secara deskriptif untuk menggambarkan bagaimana pengelolaan dokumen kepangkatan dosen sebuah PTKIN Jawa Timur menggunakan OneDrive. Hasil penelitian menunjukkan bahwa penggunaan OneDrive dalam pengelolaan  dokumen kepangkatan dosen di sebuah PTKIN di Jawa Timur dapat dilakukan melalui pembuatan folder berdasarkan tahun ajaran dan semester sesuai waktu dokumen tersebut dihasilkan. Kapasitas penyimpanan yang besar menjadikan OneDrive menjadi pilihan yang bagus yang dapat dipertimbangkan untuk mengelola dokumen secara maya. Melalui penyimpanan tersebut diharapkan sivitas akademik di salah satu PTKIN di Jawa Timur dapat dengan mudah mengakses dokumen kepangkatan di mana saja tanpa terbatas ruang dan waktu. Dapat disimpulkan bahwa OneDrive sebagai salah satu media penyimpanan di dunia maya dapat dimanfaatkan oleh sivitas akademik pada perguruan tinggi yang bersangkutan dalam pengelolaan dokumen kepangkatan dosen.
Kata Kunci: OneDrive, dokumen kepangkatan dosen, PTKIN
Abstract
This article discusses the use of OneDrive as a means of storage in cyberspace in the management of lecturer documents at one of State Islamic University (PTKIN) at East Java. The purpose of this study is to describe how the implementation of document management for lecturers in one of PTKIN at East Java environment uses OneDrive. The research method used is the qualitative method. Data was collected through interviews and documentation then analyzed by inductive method. The research data is displayed descriptively to describe how is the management of the lecturer documents at one of PTKIN at East Java. The results showed that OneDrive is used by the creation of folders based on the academic year and semester according to the time the document was produced to manage lecturers' documents at one of PTKIN at East Java. The large storage capacity makes OneDrive a good choice for managing documents virtually. Through this storage, the academic community of one of PTKIN at East Java can easily access documents anywhere without being limited by space and time. The conclusion is OneDrive as the storage media in cyberspace can be used by the academic community of the university in managing lecturer rank documents.
Electromobility in the automotive industry : A technological and geopolitical shift
Authors: Harrel Yannick
Published: February 2022

At the beginning of 2021, the very worrying shortage of Taiwanese semiconductors from TSMC and UMC for the industrial sector, and in particular the automotive sector, highlighted the crucial role of these electronic components. If we tend to consider automobiles as a chassis-engine assembly, the 1990s introduced on-board electronics as a series for reasons of safety, electro-mechanical management and comfort. This interdependence between raw materials and data has become particularly crucial in electromobility, because it manifests itself in the midst of the industrial transition of the automotive sector, which is also in geopolitical transition from West (Atlantic zone) to East (Pacific zone). The countries that hold the systemic approach will be the masters of the mobility of the future.
Terahertz Meets Untrusted UAV-Relaying: Minimum Secrecy Energy Efficiency Maximization via Trajectory and Communication Co-design
Authors: Tatar Mamaghani Milad , Hong Yi
Published: February 2022

Unmanned aerial vehicles (UAVs) and Terahertz (THz) technology are envisioned to play paramount roles in next-generation wireless communications. In this paper, we present a novel secure UAV-assisted mobile relaying system operating at THz bands for data acquisition from multiple ground user equipments (UEs) towards a destination. We assume that the UAV-mounted relay may act, besides providing relaying services, as a potential eavesdropper called the untrusted UAV-relay (UUR). To safeguard end-to-end communications, we present a secure two-phase transmission strategy with cooperative jamming. Then, we devise an optimization framework in terms of a new measure − secrecy energy efficiency (SEE), defined as the ratio of achievable average secrecy rate to average system power consumption, which enables us to obtain the best possible security level while taking UUR's inherent flight power limitation into account. For the sake of quality of service fairness amongst all the UEs, we aim to maximize the minimum SEE (MSEE) performance via the joint design of key system parameters, including UUR's trajectory and velocity, communication scheduling, and network power allocation. Since the formulated problem is a mixed-integer nonconvex optimization and computationally intractable, we decouple it into four subproblems and propose alternative algorithms to solve it efficiently via greedy/sequential block successive convex approximation and non-linear fractional programming techniques. Numerical results demonstrate significant MSEE performance improvement of our designs compared to other known benchmarks.
The directionality of interjoint neural coupling in the impaired arm post stroke
Authors: Kim Dongwon , Koh Kyung , Baghi Raziyeh , Lo Li-Chaun , Zhang Chunyang , Zhang Li-Qun
Published: February 2022

 To date, research has primarily focused on identifying and analyzing abnormal coupling in the upper extremity following stroke during gross movements such as reaching. Yet, little is known about the direction of abnormal coupling in conjunction with its degree between joints—muscles—of interest. In this study, we address the directionality of pathological neural couplings between joints, and variability in the degree of them, in the upper extremity post stroke. To evaluate the direction of interjoint coupling, joint motion and muscle activity in an involuntary mode while another joint—muscle—was voluntarily activated were assessed in comparison to those made in a volitional mode, focusing on the shoulder, elbow and wrist joints. Overall, involuntary activation of the wrist flexor in the stroke group is observed when muscles of a more proximal joint voluntarily activate (p < 0.1 and p <0.05), while activation of the wrist flexor does not lead to involuntary activation of the shoulder muscles and elbow flexor, in comparison to the healthy group. In particular, in the stroke group who is assumed to have a severe loss of the corticospinal system, the wrist extensor is subordinately activated by those about the other joints voluntarily activated (p < 0.05) while it does not cause activations of those about the other joints. These findings indicate that stroke-caused synergies could be directional, implying the existence of a cortical source and/or neural pathway for a muscle that is not paired with that for other muscles.
Do You Need a Distributed Ledger Technology Interoperability Solution?
Authors: Belchior Rafael , Riley Luke , Hardjono Thomas , Vasconcelos André , Correia Miguel
Published: February 2022

Entrepreneurs, enterprises, and governments are using distributed ledger technology (DLT) as a component of complex information systems, and therefore interoperability capabilities are required. Interoperating DLTs enables network effects, synergies and, similarly to the rise of the Internet, it unlocks the full potential of the technology. However, due to the novelty of the area, interoperability mechanisms (IM) are still not well understood, as interoperability is studied in silos. Consequently, choosing the proper IM for a use case is challenging.

Our paper has three contributions: first, we systematically study the research area of DLT interoperability by dissecting and analyzing previous work. We study the logical separation of interoperability layers, how a DLT can connect to others (connection mode), the object of interoperation (interoperation mode), and propose a new categorization for IMs. Second, we propose the first interoperability assessment for DLTs that systematically evaluates the interoperability degree of an IM. This framework allows comparing the potentiality, compatibility, and performance among solutions.

Finally, we propose two decision models to assist in choosing an IM, considering different requirements. The first decision model assists in choosing the infrastructure of an IM, while the second decision model assists in choosing its functionality.
Invisible Geolocation Signature Extraction From a Single Image
Authors: Choi Jisoo , Wong Chau-Wai , Hajj-Ahmad Adi , Wu Min , Ren Yanping
Published: February 2022

Published in IEEE Transactions on Information Forensics and Security (T-IFS) on 23 June 2022. This version on TechRxiv contains supplemental material.
On the Performance of RIS-Assisted Communications with Direct Link in κ-µ Shadowed Fading Channels
Authors: Al-Dweik Arafat , Al-Rimawi Ashraf
Published: February 2022

Reconfigurable intelligent surfaces (RISs) is a new technology that can
be used to create a virtual line-of-sight (LOS) link when the direct link is
blocked. The signal-to-noise ratio (SNR) can be significantly improved by
optimizing the reflecting elements’ phases to make the reflected signals add
coherently at the receiver. Nevertheless, the RIS cannot control the phase of
the direct link if it exists. In such scenarios, the RIS phase can still be controlled
such that the direct and reflected signals add coherently, however, the gain
obtained by using the RIS might be hindered. Therefore, this paper considers
the performance analysis of such scenarios where a novel analytical framework
is developed to evaluate the SNR, outage probability and bit error rate (BER).
To capture a broad range of fading conditions, the channels are modeled as
independent but not identically distributed generalized κ-µ shadowed fading
channels. The Laguerre expansion is used to derive the probability density
function (PDF) and cumulative distribution function (CDF) of the instantaneous
channel fading, which are used to derive the PDF and CDF of the instantaneous
SNR. The paper also considers deriving the asymptotic PDF, CDF, moment
generating function (MGF) of the SNR, as well as the outage probability and
BER. The derived expressions are used to evaluate the system performance in
various fading environments such as Rayleigh, One-Sided Gaussian, Nakagami-m , Rician, and Rician-shadowed distributions since they are special cases
of the κ-µ shadowed
distribution. The obtained analytical results corroborated by Monte Carlo
simulation show that a strong direct link can generally eliminate the gain
obtained using the RIS. Therefore, the overhead required for the RIS operation
becomes a burden on the network and may cause severe throughput degradation. In
such scenarios, the RIS involvement should dynamically controlled to avoid
unnecessary complexity and throughput reduction.
Decomposing Satellite-Based Classification Uncertainties in Large Earth Science Datasets
Authors: Ortiz Pedro , Orescanin Marko , Powell Scott , Petkovic Veljko , Marsh Benjamin
Published: February 2022

Collection of increasingly voluminous multi-spectral data from multiple instruments with high spatial resolution has posed both an opportunity and a challenge for maximizing their utilization, analysis, and impact. Obtaining accurate estimates of precipitation globally with high temporal resolution is crucial for assessing multi-scale hydrologic impacts and providing a constraint for development of numerical models of the atmosphere that provide weather and climate predictions. Precipitation type classification plays an important role in constraining both the inverse problem in satellite precipitation retrievals and latent heat transfer within weather prediction simulations. Precipitation type, however, is often reported deterministically, without uncertainty attached to an estimate. Machine learning techniques are capable of extracting content of interest from large datasets and accurately retrieving discrete and continuous properties of physical systems, but with limited insights to the retrieval components–such as errors and the physical relationship between the observed and retrieved properties. To address this shortcoming, we perform precipitation type classification to introduce a novel tool for decomposing errors of satellite-retrieved products. We use Bayesian neural networks to map Global Precipitation Measurement mission Microwave Imager observations to Dual-frequency Precipitation Radar-derived precipitation type, which perform comparably to deterministic models, but with the added benefit of providing well calibrated uncertainties. Through uncertainty decomposition, we demonstrate well calibrated uncertainties as useful for making decisions concerning high uncertainty predictions, model selection, targeted data analysis, and data collection and processing. Additionally, our Bayesian models enable mathematical confirmation of a data distribution change as the cause for an unacceptable decline in model accuracy.
Omni-Directional Signal Broadcasting for Terahertz Communications in 6G Mobile Systems
Authors: Jiang Wei , Schotten Hans Dieter
Published: February 2022

To realize a unprecedentedly high data speed in terabits-per-second (Tbps), the upcoming sixth-generation (6G) mobile communications system needs to utilize the abundant spectrum in the terahertz bands. However, high-frequency transmission suffers severe propagation loss and short transmission distance, which would be heavily relies on a large-scale antenna array to reap high beamforming gain, used to compensate for such a loss. But beamforming over an antenna array, especially a large-scale array, raises a problem of omni-directional coverage during the phase of initial access, where a base station is required to broadcast synchronization signals and master system information to each user within its coverage. Therefore, this paper aims to propose a novel omni-directional beamforming scheme, providing instantaneous gain equally in all directions by forming a pair of complementary beams. Numerical results verify that it can achieve omni-directional coverage with the optimal performance that remarkably outperforms the previous scheme called random beamforming.