bluuebunny/crossref_metadata_2025 huggingface dataset:
The key to improving the beauty of the giant retaining wall in valleys: Increasing visual extension
Authors: Song Jialu , Zhou Yanzuo , Xiao Weiyang , Zeng Qin , Wu Yixuan , Song Huixing
Published: June 2023

The retaining wall is a passive engineering measure to prevent and control unsafe factors caused by rock collapse in the valleys. Existing studies have mainly focused on its functional robustness and safety features, with few exploring its visual quality in the landscape. A multiple regression analysis was applied to evaluate the Scenic Beauty Estimation (SBE) of the giant retaining wall in Jiuzhaigou’s (a world natural heritage site) Heye Village, then the factors affecting SBE were analyzed. It is found that enhancing the sense of perspective and spatial hierarchy of retaining-wall murals in narrow roads contributes to the extension of observers’ sight, which is the key to improving SBE. Furthermore, the showcase of folk culture in murals can realize the beautification function of the giant retaining walls. In addition, the SBE of giant retaining walls is also linked to coordination, where the walls embellished with the natural landscape and folk culture murals have better SBE performance than those with local stones. This study provides a reference for constructing scenic beauty after fulfilling the safety function of retaining wall engineering.
Unlocking the Secrets of Streptococcus suis: A peptidomics comparison of virulent and non-virulent serotypes 2, 14, 18, and 19
Authors: Chaiden Chadaporn , Jaresitthikunchai Janthima , Phaonakrop Narumon , Roytrakul Sittiruk , Kerdsin Anusak , Nuanualsuwan Suphachai
Published: June 2023

Streptococcus suis (S. suis) is an important bacterial pathogen, that causes serious infections in humans and pigs. Although numerous virulence factors have been proposed, their particular role in pathogenesis is still inconclusive. The current study explored putative peptides responsible for the virulence of S. suis serotype 2 (SS2). Thus, the peptidome of highly virulent SS2, less prevalent SS14, and rarely reported serotypes SS18 and SS19 were comparatively analyzed using a high-performance liquid chromatography-mass spectrometry method (LC-MS/MS). Six serotype-specific peptides, 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (DapH), alanine racemase (Alr), CCA-adding enzyme (CCA), peptide chain release factor 3 (RF3), ATP synthase subunit delta (F0F1-ATPases) and aspartate carbamoyltransferase (ATCase), were expressed moderately to highly only in the SS2 peptidome with p-values of less than 0.05. Some of these proteins are responsible for bacterial cellular stability; especially, Alr was highly expressed in the SS2 peptidome and is associated with peptidoglycan biosynthesis and bacterial cell wall formation. This study indicated that these serotype-specific peptides, which were significantly expressed by virulent SS2, could serve as putative virulence factors to promote its competitiveness with other coexistences in a particular condition. Further in vivo studies of these peptides should be performed to confirm the virulence roles of these identified peptides.
Study on the high-temperature and aging properties of agricultural waste-modified asphalt based on rheology
Authors: Zhang Renwei , Ji Zhiyuan
Published: June 2023

The modifier of road materials from agricultural waste (AW) as raw material has been widely noticed. Considering the environmental impact of AW treatment and the National policy on the promotion of resource reuse, the feasibility of four AW (namely, bamboo powder, rape straw, corn cob, and wheat straw) for styrene butadiene styrene (SBS) asphalt modification is studied from the properties and mechanism perspectives. Through properties evaluation tests (such as the dynamic shear rheometer, multiple stress creep recovery, and rotating thin film oven test), the influence of four AW and different mixing amounts on the properties of SBS modified asphalt pavement is analyzed from the aspects of high-temperature deformation resistance and anti-aging properties. The results reveal that the four AW can improve the SBS asphalt’s high-temperature deformation resistance and anti-aging properties, among which rape straw has the most significant improvement effect. In addition, through the fourier transform infrared spectroscopy test, the microscopic mechanism of the AW/SBS composite modified asphalt binder is revealed from the functional groups. The analysis shows that the AW is physically mixed with the SBS asphalt binder, which inhibits the growth of sulfoxide groups and the cracking of the SBS modifier during aging.
Clinical course of new-onset Crohn’s disease in children and adolescents in dependency of age, initial location, initial severity level and therapy over the period 2000–2014 based on the Saxon Pediatric IBD-Registry in Germany
Authors: Dong Fan , Kern Ivana , Weidner Jens , Kügler Kathleen , Rothe Ulrike , Amin Makan , Laaß Martin W. , Flemming Gunter , Winkler Ulf , Richter Thomas , Kugler Joachim , Manuwald Ulf
Published: June 2023

Objective

In Saxony, the incidence of Crohn’s disease (CD) in children and adolescents increased significantly from 3.3 per 100,000 person-years in 2000 to 5.1 in 2014. The aim of this study was to describe the initial characteristics and the clinical course of CD in children and adolescents and to identify drug treatment options associated with an advantage for a mild course or remission.

Methods

Clinical data were collected from patients who suffered from inflammatory bowel disease (IBD) and were recruited in the Saxon Pediatric IBD-Registry. All children newly diagnosed with CD in this registry in Saxony between 2000 and 2014 were included in this registry study. Characteristics such as age, disease location and extra-intestinal manifestations at diagnosis were accessed. The severity level of the disease at diagnosis as well as at follow-up were analysed by PCDAI index. Patients were divided into 3 groups according to length of follow-up: 1–3 years, 4–6 years and 7–9 years after diagnosis. A logistic regression model was conducted to examine which baseline parameters are associated with disease progression.

Results

There were 338 children and adolescents with CD included in this registry study. At diagnosis, the median age of patients was 12.0 (0.7–14.9), 61.5% (n = 208) of the patients were male. The most common disease location observed in pediatric CD patients was the L3 (55%, n = 176). Patients aged 10–14 years were significantly more likely to present an L2 than patients aged 0–4 years (80.3%, n = 53 vs. 19.7%, n = 13, p = 0.01). During the follow-up, data from 71.3% (n = 241) othe patients were available. Disease activity measured by PCDAI decreased in 47.7% (n = 115) of the patients, 40.7% (n = 98) of the patients were stable and increased in 11.6% (n = 28) of the patients. Patients with intermediate/severe disease at onset were more likely to have an active disease at the end of follow up, too (p = 0.00). Logistic regression analysis of the initial characteristics showed that the age at diagnosis, gender, initial location and initial extra-intestinal manifestation are not associated with the progression of the disease (p>0.05). Furthermore, drug treatment options could be identified from our data, which are associated with benefits for a milder course or remission.

Conclusion

From 2000 to 2014, the health status of most pediatric patients with CD had improved or remained stable. Initial characteristics including age at diagnosis, initial localization and initial extra-intestinal manifestation are not associated with the progression of the disease, only the initial activity by PCDAI.
LINC01117 inhibits invasion and migration of lung adenocarcinoma through influencing EMT process
Authors: Liu Linjun , Ren Wenjia , Du Licheng , Xu Ke , Zhou Yubai
Published: June 2023

Background

Studying the mechanism of action of LncRNAs in lung adenocarcinoma (LUAD) is of great importance for an in-depth understanding of the molecular mechanism of lung adeno carcinogenesis and development.

Objective

The aim is to identify a long non-coding RNA LINC01117 that is specifically and highly expressed in LUAD cells and to investigate its biological functions and molecular mechanisms in LUAD cells, providing a new potential target for targeting LUAD therapy.

Methods

This study used publicly available data downloaded from The Cancer Genome Atlas (TCGA) database. Construction of siRNA and overexpression plasmid-packed lentiviral constructs were used to knock down and increase the expression of LINC01117 in LUAD cells. The effect of LINC01117 on LUAD cell migration and invasion was verified by scratch assays and Transwell assays. Western blot assays were performed to verify the effect of knocking down LINC01117 expression on key proteins of the EMT process. The effect of overexpression and knockdown LINC01117 expression on key proteins of the EMT process and the nuclear and cytoplasmic distribution of YAP1, a key effector molecule of the Hippo pathway, was verified by Western blot assays.

Results

LINC01117 expression was upregulated in LUAD tissues and cell lines. Clinical correlation and prognostic analyses showed that LINC01117 was associated with poorer clinical features (staging and N classification) and poorer prognosis and could be analyzed as an independent prognostic factor. Cell migration and invasion were significantly inhibited in the knockdown group compared to the control group; in contrast, cell migration and invasion were promoted in the overexpression group. Overexpression of LINC01117 resulted in down-regulation of E-cadherin expression and increased expression levels of N-cadherin, vimentin, ZEB1, snail and slug; in contrast, knockdown of LINC01117 appeared to have the opposite effect. Furthermore, knockdown of LINC01117 increased the enrichment of YAP1 protein in the cytoplasm and reduced its level in the nucleus; overexpression of LINC01117 produced the opposite intracellular distribution results.

Conclusions

LINC01117 was highly expressed in LUAD, and knockdown of LINC01117 significantly inhibited the migration and invasion of LUAD cells, while overexpression of LINC01117 significantly promoted the migration and invasion of LUAD cells, and affected the EMT process, and was able to alter the distribution of YAP1 in the nucleus and cytoplasm. This suggests that LINC01117 may regulate the activity of the Hippo pathway by altering the nuclear and cytoplasmic distribution of YAP1, which in turn induces the EMT process in lung adenocarcinoma cells and thus exerts a pro-cancer effect. It suggests that LINC01117 may play a key role in the occurrence and development of LUAD.
Identifying important factors for successful surgery in patients with lateral temporal lobe epilepsy
Authors: Kim Jae Rim , Jo Hyunjin , Park Boram , Park Yu Hyun , Chung Yeon Hak , Shon Young-Min , Seo Dae-Won , Hong Seung Bong , Hong Seung-Chyul , Seo Sang Won , Joo Eun Yeon
Published: June 2023

Objective

Lateral temporal lobe epilepsy (LTLE) has been diagnosed in only a small number of patients; therefore, its surgical outcome is not as well-known as that of mesial temporal lobe epilepsy. We aimed to evaluate the long-term (5 years) and short-term (2 years) surgical outcomes and identify possible prognostic factors in patients with LTLE.

Methods

This retrospective cohort study was conducted between January 1995 and December 2018 among patients who underwent resective surgery in a university-affiliated hospital. Patients were classified as LTLE if ictal onset zone was in lateral temporal area. Surgical outcomes were evaluated at 2 and 5 years. We subdivided based on outcomes and compared clinical and neuroimaging data including cortical thickness between two groups.

Results

Sixty-four patients were included in the study. The mean follow-up duration after the surgery was 8.4 years. Five years after surgery, 45 of the 63 (71.4%) patients achieved seizure freedom. Clinically and statistically significant prognostic factors for postsurgical outcomes were the duration of epilepsy before surgery and focal cortical dysplasia on postoperative histopathology at the 5-year follow-up. Optimal cut-off point for epilepsy duration was eight years after the seizure onset (odds ratio 4.375,p-value = 0.0214). Furthermore, we propose a model for predicting seizure outcomes 5 years after surgery using the receiver operating characteristic curve and nomogram (area under the curve = 0.733; 95% confidence interval, 0.588–0.879). Cortical thinning was observed in ipsilateral cingulate gyrus and contralateral parietal lobe in poor surgical group compared to good surgical group (p-value < 0.01, uncorrected).

Conclusions

The identified predictors of unfavorable surgical outcomes may help in selecting optimal candidates and identifying the optimal timing for surgery among patients with LTLE. Additionally, cortical thinning was more extensive in the poor surgical group.
Gender Integration for Climate Action: A Review of Commonwealth Member Country Nationally Determined Contributions
Authors: Secretariat Commonwealth
Published: June 2023

This report, updated from the first edition published in 2021, presents a macro-level overview of the extent of gender integration in Intended Nationally Determined Contributions (INDCs), and new or revised Nationally Determined Contributions (NDCs) by Commonwealth member countries submitted to the United Nations Framework Convention on Climate Change (UNFCCC) under the 2021 revision cycle. Since the first edition of this report was published, a further 27 updated NDCs have been submitted, and Gabon and Togo have joined as Commonwealth member countries, bringing the total updated NDCs submitted to 47 of the 56 member countries.

The Earth’s climate is a system influenced by many complex interlinked feedback loops. Gender equality and the empowerment of women is a global Sustainable Development Goal (SDG), also subject to many influences depending on context and national circumstances. While there is no doubt that climate and gender equality are intersectional issues, both are stand-alone goals under the SDGs, and jostle for position with other social and economic development priorities.

Presenting assessments of NDCs made using a quantitative and qualitative framework, and including an eight-point scale to illustrate the journey from ‘no gender integration’ through to ‘gender awareness, sensitivity and responsiveness’, the report showcases existing best practices for countries to emulate, and proposes a set of recommendations that can be followed during future NDC revision processes. Furthermore, it identifies critical gaps common to most NDCs, and provides a baseline for Commonwealth Secretariat interventions towards policy development, finance, technology and capacity building for implementation of gender-inclusive climate action in Commonwealth member countries.
Commonwealth Cybercrime Monitor
Authors: Secretariat Commonwealth
Published: June 2023

The Commonwealth Cybercrime Monitor (CCM) contains a brief synopsis and links to selected cybercrime cases collected from different countries across the Commonwealth. It will be of interest to policymakers, academics and practitioners involved in cybercrime policymaking, investigation, prosecution and adjudication. It is designed to assist Commonwealth member countries to strengthen their anti-cybercrime and cybersecurity legislative, policy, institutional and
multilateral frameworks.

The cases covered in the present edition of the CCM include online harassment, ransomware, child pornography, money laundering and electronic fraud cases.
Addressing Online Violence Against Women and Girls in the Commonwealth Europe Region
Authors: Secretariat Commonwealth
Published: June 2023

This report contributes to the Commonwealth study on online violence against women and girls (OVAWG) and considers the prevalence of online violence and the role of bystanders as well as therelevant laws, institutions, policies and practices to address the problem in the European region of the Commonwealth, namely Cyprus, Malta and the United Kingdom of Great Britain (England, Scotland and Wales) and Northern Ireland (UK).

The report highlights the complex nature of OVAWG and the difficulties associated with differences in terminology resulting in inconsistent data collection and varied legal responses across the European region of the Commonwealth. It also details the role of bystanders and their criminal or civil liability that, it argues, are relatively new considerations in the OVAWG space. An understanding of the nature and presentation of OVAWG is required by bystanders, including the impact on victims to drive action.
Fiscal Policy Options for Resilient and Sustainable Development
Authors: Secretariat Commonwealth
Published: June 2023

Creating enabling environments and the capacity to access and generate multidimensional financing for development, climate change and enhanced resilience, remains challenging amid global pressures. One feasible approach is to revisit the criteria for financing allocation and the management of earmarked international transfers and debt relief.

This paper focuses on fiscal policy options for resilient and sustainable development. An appropriate design and mix of national taxes would help raise revenues efficiently, reduce the cost of doing business and the barriers to exports, and encourage economic integration to counteract disruptions in global value chains.
Desregulación en el Mercado del Suelo por parte del Estado Chileno y su impacto en la Política Habitacional
Authors: Muñoz Moya Oscar , Lizana Fuentes Álvaro , Navarrete Jiménez Boris , Rojas Astorga Carlos , Vallespir Lizama Felipe
Published: June 2023

En las siguientes páginas se exponen datos relevantes para entender la desregulación en el mercado del suelo, y la ejemplificación de la violencia estatal en el desarrollo de la política habitacional y la planificación territorial, la cual desde la década de los noventa ha generado profundas desigualdades basadas en el modelo neoliberal y de libre mercado.
Testing Various Poisons and Substances Against Indoor Home-Garden Aphids
Authors: Meyer Gabriel
Published: June 2023

Peppermint has been an area of interest for controlling aphid populations in the literature for decades, but it seems to be concerned with industrial applications more than everyday use. Aphid infestations indoors present a novel need for an organic pesticide that sufficiently culls infestations without risk to the household. Everyday access to peppermint substances were then obtained and used in various solutions to test their efficacy in a new environment. Dish soap has also been presented as a possibility, and is often reported to work by home gardeners. It was hypothesized that water would do nothing, Sevin would remove the aphid population entirely, and that dish soap and peppermint substances would be indistinguishable from Sevin. N=7 solutions were tested, being various solutions of water, dish soap, peppermint oil or paste extract, as well as the insecticide Sevin. Peppermint oil mixed with dish soap was effective in reducing the aphid population, as well as peppermint paste extract along with Sevin. However, Sevin and the paste did severe damage to the plants and are not recommended for household use.
Investigation of Bleaching of Cotton Fabrics with UV-TiO2
Authors: Eren Semiha , Akarsu Özenç Aliye
Published: June 2023

Titanium dioxide exhibits photocatalytic properties under ultraviolet (UV) irradiation. In this study, an environmentally friendly, fast and efficient technique for bleaching cotton fabrics is presented, utilising the photocatalytic property of TiO2. Raw cotton fabric samples were treated with TiO2-containing and TiO2-free treatment solutions (hydrogen peroxide and sodium hydroxide) under UV irradiation in order to bleach the samples. The results showed that cotton fabrics treated with TiO2 were bleached satisfactorily without severe strength loss.
The everyday life of a young landowner on the example of the Roman Bniński Junior
Authors: Studnicka-Mariańczyk Karolina Studnicka-Mariańczyk , Czerniecka-Haberko Anna
Published: June 2023

This article has been written based on previously unpublished correspondence of the Bniński family, carried on between August 13, 1876 and May 5, 1890. The sender was Roman Bniński (the father), and the addressee was his son, also Roman. One of the letters was written to his sons Roman and Hilary. This remarkable correspondence allows to recreate daily life of the landed gentry living in Podolia. It also provides an opportunity to look into everyday matters and witness life in Vinnytsia palace. The father’s correspondence with his son enables to recreate aspects of Roman Bniński’s life, his relations with the family members, his attitude towards education, friendships and the forms of spending free time.
Editorial
Authors: Wąsikiewicz-Firlej Emilia , Ballweg Sandra , Masterson Mary , Daase Andrea , Farrell Angela
Published: June 2023

Institutional and family support for multilingual development. Issue under the auspices of the MaMLiSE project (Majority and Minority Languages in School Environment: Helping teachers, pupils and parents) https://mamlise.amu.edu.pl/
Bericht über die XVII. Internationale Tagung der Deutschlehrerinnen und Deutschlehrer „mit. sprache.teil.haben“. Wien, 15.–20. August 2022
Authors: Malloggi Patrizio
Published: June 2023

Bericht über die XVII. Internationale Tagung der Deutschlehrerinnen und Deutschlehrer „mit. sprache.teil.haben“. Wien, 15.–20. August 2022
Language-sensitive teaching as an emergent response to increasing linguistic diversity in Irish post-primary schools: Challenges, opportunities and implications for teacher education
Authors: Farrell Angela , Masterson Mary , Daly Michelle
Published: June 2023

The 21st century has been characterised by an unprecedented growth in transnational migration with education systems in many countries challenged to address the implications of this ongoing global phenomenon. This paper reports on a recent study that was undertaken amongst teachers and school managers in post-primary state schools in Ireland to explore the current position regarding language-sensitive teaching as an emergent response to the growing reality of linguistic diversity in schools. Bottom-up research of this kind is vital as it can shed light on the perceptions and experiences of the key stakeholders involved in order to determine their related professional needs and shape future directions in teacher education in this area. The key findings show that language-sensitive teaching remains in its infancy in the Irish post-primary educational context with an urgent need for teacher awareness-raising and upskilling in relation to this approach and its implementation in different subject classrooms. The research has also indicated that language support teachers can play a central role in developing language-sensitive teaching at the whole school level but this potential remains largely under-exploited in the Irish post-primary educational context.
English and other languages in a plurilingual pedagogical approach: A case study from northern Italy
Authors: Irsara Martina
Published: June 2023

Language teaching constantly needs to be adapted to changing societal realities, such as the spread of English as an international language or the growing linguistic complexity in Europe. A key question is whether and how languages could be treated together in school programmes to cater to a multilingual milieu. This article analyses a plurilingual pedagogical approach that is adopted in a few primary schools in the Italian province of South Tyrol. The research is a qualitative case study and draws on various theoretical perspectives, including the method model developed by Richards and Rodgers (1982, 2001, 2014). The dataset comprises analogue and digital data gathered through participant observation, field notes, personal communications, audio recordings, and school documents. Results show how a multilingual turn has taken root in the context examined, while reinforcing English acquisition.
Die Fremdsprache Deutsch als Unterrichtssprache im DaF-Unterricht – das Fallbeispiel Polen
Authors: Badstübner-Kizik Camilla , Bielicka Małgorzata
Published: June 2023

The first step in acquiring a language is to extract information from the environment. The research conducted in this field mainly focuses on two aspects: the role of language input as a trigger for language acquisition processes and the corrective function of language. The paper discusses classroom language as one of the most important sources of language input in foreign language teaching, whereby special attention is given to the quality and quantity of language input provided by Polish teachers of German as a foreign language. After presenting an overview of relevant research findings, recommendations for the use of foreign language in classroom communication are given, with reference to the example of German as a foreign language.
Możliwość zastosowania instytucji fundacji rodzinnej w rolnictwie
Authors: Bieluk Jerzy
Published: June 2023

Celem rozważań jest sformułowanie odpowiedzi na pytania dotyczące możliwości zastosowania instytucji fundacji rodzinnej do prowadzenia działalności rolniczej oraz regulowania kwestii następstwa w gospodarstwach rolnych. Analiza ustawy o fundacji rodzinnej prowadzi do wniosku, że ułatwia ona sukcesję i zapobieżenie podziałowi majątku spadkowego. Jednak rozwiązania podatkowe dotyczące prowadzenia działalności rolniczej przez fundację rodzinną są nieprecyzyjne i nie pozwalają na jednoznaczne stwierdzenie, czy fundacja rodzinna może zajmować się działalnością rolniczą. Autor skłania się do wniosku, iż działalność rolnicza powinna być działalnością dozwoloną w ramach fundacji rodzinnej. Jednak podjęcie działalności rolniczej w ramach fundacji rodzinnej w praktyce powinno łączyć się z uzyskaniem w tym zakresie odpowiedniej podatkowej interpretacji indywidualnej, zabezpieczającej przed ryzykiem podatkowym.
Introduction to the special issue on English medium instruction: Areas of research needing urgent attention
Authors: Macaro Ernesto , Rose Heath
Published: June 2023

English medium instruction (EMI), both in higher and secondary education, is now a well-established field of education research and, indeed, many applied linguistics journals are publishing regularly on a variety of EMI topics. Recently, a new journal, Journal of English-Medium Instruction, has been established that is dedicated entirely to this area of academic enquiry. Recent years have also seen several special issues emerge on topics within EMI in journals such as Applied Linguistics Review (published advanced online), System (in 2023), and TESOL Quarterly (in 2018).
A review of polyunsaturated fatty acids (PUFA) of marine zoosporic microorganisms and their commercialization
Authors: Saikia Diganta Kumar , Chikkaputtaiah Channakeshavaiah , Velmurugan Natarajan
Published: June 2023

Long-chain polyunsaturated fatty acids (LC-PUFA) are nutritionally and pharmacologically well-recognized beneficial compounds widely used as nutrient supplements for various applications. As the human body cannot accomplish de novo synthesis of PUFA, we depend on exogenous bioresources for the supply of these essential PUFA for day-to-day activities. The PUFA global market is expected to reach about US$ 9.7 billion by 2032. The recent drop in natural fish catch and global climate change severely hamper the global PUFA supply chain. As a sustainable, promising resource, marine zoosporic microorganisms are considered to be safe and alternative primary producers of beneficial PUFAs for direct and indirect human consumption. However, by considering the limitations associated with strain efficiency, final product yield and production cost, more viable low-cost production strategies and establishment of highly efficient, stable, high production cell lines specific for marine zoosporic microbes are essential to meet global PUFA market demand. The exploration of the latest techniques for research and development could shape the dynamics better for the global market for marine zoosporic organism-based PUFA products. Therefore, this review first summarizes low-cost production and strain improvement strategies, and later highlights the advantages and commercial prospects for marine zoosporic microbe-derived PUFA.
Identification and tracing of radionuclides in low- and medium-activity liquid radwaste sources of G.A. Siwabessy reactor
Authors: Sriyono Sriyono , Saprudin Deden , Rafi Mohamad , Sunaryo Geni R. , Luhur Nugraha , Muslimu Fahmi A.
Published: June 2023

The liquid radioactive waste generated by the G.A. Siwabessy reactor (RSG-GAS) is categorized into low-activity liquid radwaste (LALR) and medium-activity liquid radwaste (MALR). The radionuclide content of both LALR and MALR can use as an indicator of the structural integrity of the reactor’s systems, structures, and components (SSC). To evaluate the degradation of the reactor SSC, the radionuclide species were identified, and their activities were measured using gamma spectroscopy. Based on the identified radionuclides, the process of their formation can be traced. The radionuclides identified in LALR were 24Na, 51Cr, 59Fe, 60Co, 65Zn, and 124Sb, while the radionuclides in MALR were 24Na, 51Cr, 58Co, 59Fe, 60Co, 65Ni, 65Zn, 89Kr, 90Kr, 109Cd, 131I, 132I, 140Ba, 137Cs, 146Ce, and several others. The radionuclides found can be classified into corrosion product activation (60Co, 65Zn, 51Cr, 59Fe, 24Na, 65Ni), topaz impurities activation (51Cr, 59Fe, 60Co, 65Zn), fission product (90Kr, 140Ba, 131I, 137Cs, etc.), and demineralized water impurities activation (51Cr, 59Fe, 65Zn, 60Co, etc.). After comparing the activity value of each radionuclide with the limit value in the safety analysis report document, we can conclude that the activity of each one is below the required level. It can infer that the structural integrity of reactor SSC is still well maintain. During routine monitoring, the radionuclide content in the primary coolant fluctuates depending on the reactor load. The concentration of radionuclides detected varies when a large or small number of research samples are loaded onto the core. Nevertheless, their activities remain within the required safety limits.
IV. Nascitur ex contumelia: What did contumelia in the actio iniuriarum really mean?
Authors: Drevikovsky Janek
Published: June 2023

Contumelia, which for the jurists was the definition of the delict iniuria, has been poorly understood by most modern scholarship. The term does not mean ‘contempt’ or any other attitude of the mind; instead, examination of all instances of the word contumelia predating 300 CE demonstrates that, in both lay and legal literature, it meant a kind of degradation or insult which, when judged against Roman rubrics of status and hierarchy, derogated from the honour of a free citizen. In juristic writings on iniuria, contumelia had an objective function, describing the typical fact-patterns proscribed by the praetorian edicts and rationalising those edicts’ piecemeal approach under one convenient lay concept. Contumelia was not iniuria’s mental requirement and, since it did not mean contempt, the delict was simply uninterested in whether a defendant had demonstrated a contemptuous or belittling attitude towards his victim.
VIII. La versión griega de la constitución Imperatoriam en el manuscrito Parisinus gr. 1366
Authors: Reinoso-Barbero Fernando
Published: June 2023

Examination of the Greek version of the constitution Imperatoriam (Βασιλικῆς) from the perspective of the seven manuscripts containing it, especially the most important of them, the Parisinus gr. 1366 which, inexplicably, was not used by the last editors of that text (Groningen 2010). We now transcribe the unpublished contents of this manuscript which demonstrate that (1.) the Βασιλικῆς was translated by Theophilus, and (2.) he included it as an introductory lesson within the first book of his Paraphrase. We also show here that the five manuscripts which have not preserved the Βασιλικῆς, nevertheless had it originally.
Wissensmanagement in KMU
Authors: Schiedermair Ina , Kick Elena , Baumgartner Marco , Kopp Tobias , Kinkel Steffen
Published: June 2023

Demografischer Wandel und Fachkräftemangel stellen Unternehmen vor die Herausforderung, geschäftsrelevantes Wissen nachhaltig, transparent und strukturiert zu sichern und intern zu verteilen. Dabei spielen bestimmte Mitarbeitende, zum Beispiel aufgrund ihres exklusiven Wissens, eine besondere Rolle. Der Beitrag analysiert die Charakteristika dieser Schlüsselpersonen auf Basis von sieben leitfadengestützten Interviews mit Führungskräften und leitet daraus Implikationen für das interne Wissensmanagement ab.
Němčice: research at a key La Tène site in Moravia
Authors: Čižmář Ivan , Čižmářová Jana
Published: June 2023

The central agglomeration of Němčice in Moravia was one of the most important archaeological sites of the La Tène period in Central Europe. This article presents current interdisciplinary research on the site, including the discovery of the earliest glass workshop in Transalpine Europe.
Digital Twin–Enabled Machine Learning for Smart Manufacturing
Authors: Jain Sanjay , Narayanan Anantha
Published: June 2023

Production control problems have been solved using analytical and simulation models, but their applications are limited because of the substantial execution times that they generally require. Applications such as order promising do not allow the time to execute such models. This paper proposes confluence of two Industry 4.0 technologies, machine learning and digital twins, for such time-sensitive applications. Surrogate models developed using machine-learning approaches can provide quick responses, but they need large amounts of data collected from operations over long periods to provide answers with acceptable accuracy. A digital twin of manufacturing operations can be used to drastically reduce the time to generate the data needed by machine-learning approaches. This paper describes the concept for digital twin–enabled machine learning and an implementation for order promising using a hypothetical job shop problem. Data are generated across a range of scenarios by the digital twin of the job shop and analyzed using a Gaussian process regression approach. A meta model is generated that is capable of estimating cycle times based on the current situation in the job shop. The example implementation demonstrates the advantages offered by the approach for production planning and control level applications.
Microbiota and Diapause-Induced Neuroprotection Share a Dependency on Calcium But Differ in Their Effects on Mitochondrial Morphology
Authors: Delgado Scarlett E. , Urrutia Arles , Gutzwiller Florence , Chiu Chiayu Q. , Calixto Andrea
Published: June 2023

The balance between the degeneration and regeneration of damaged neurons depends on intrinsic and environmental variables. In nematodes, neuronal degeneration can be reversed by intestinal GABA and lactate-producing bacteria, or by hibernation driven by food deprivation. However, it is not known whether these neuroprotective interventions share common pathways to drive regenerative outcomes. Using a well established neuronal degeneration model in the touch circuit of the bacterivore nematodeCaenorhabditis elegans, we investigate the mechanistic commonalities between neuroprotection offered by the gut microbiota and hunger-induced diapause. Using transcriptomics approaches coupled to reverse genetics, we identify genes that are necessary for neuroprotection conferred by the microbiota. Some of these genes establish links between the microbiota and calcium homeostasis, diapause entry, and neuronal function and development. We find that extracellular calcium as well as mitochondrial MCU-1 and reticular SCA-1 calcium transporters are needed for neuroprotection by bacteria and by diapause entry. While the benefits exerted by neuroprotective bacteria require mitochondrial function, the diet itself does not affect mitochondrial size. In contrast, diapause increases both the number and length of mitochondria. These results suggest that metabolically induced neuronal protection may occur via multiple mechanisms.
Posveta geniju carske kuće (Genius domus Augusta) iz Oneja
Authors: Jadrić-Kučan Ivana , Banovac Ivana
Published: June 2023

Članak donosi sliku carskog štovanja u rimskom Oneju pri čemu je glavna pozornost usmjerena na žrtvenik Božanskog Augusta, božice Rome i Genija carske obitelji (Genius domus Augusta). Riječ je o vrlo zanimljivom kultnom spomeniku, ne samo zbog njegove višestruke posvećenosti nego i zbog činjenice da ga podiže pomoćna vojna jedinica, Cohors I Gallica Voluntariorum, što je ujedno i njezin prvi spomen u provinciji Dalmaciji.
Kasnoantičko i ranosrednjovjekovno groblje u Novigradu. Preliminarni rezultati istraživanja
Authors: Gergeta Sotončić Kristina
Published: June 2023

Od kraja travnja do početka lipnja 2021. godine na području nekadašnje depandanse hotela Stella Maris u Novigradu provedeno je zaštitno arheološko istraživanje. Ono je rezultiralo definiranjem prostora širenja kasnoantičkog i ranosrednjovjekovnog groblja sub divo koje je gravitiralo oko crkve sv. Andrije sjeverno od današnje župne crkve. Grobovi su oštećeni formiranjem vrtova i, poslije, izgradnjom zgrade turističke namjene početkom 60-ih godina 20. stoljeća. Utvrđeno je nekoliko tipologija grobova. Prevladava ukapanje u grobove formirane od neobrađenih vapnenačkih ploča koje su nejednako lomljene i nejednake veličine, položene jedna do druge te okomito usađene u tlo. Prisutni su i ukopi u dijelom zidane grobove te slobodno polaganje pokojnika na zdravicu. Ostatci dviju kasnoantičkih amfora i brojni ulomci amfora otkriveni u otpadnim jamama upućuju na najraniju fazu ukopa. Položaj grobova u južnom dijelu istražene površine bio je definiran suhozidima, koji su u naknadnoj fazi ukapanja preslojeni grobovima. Grobove, na temelju tipologije pokretnih nalaza, od kojih prevladava grubo kuhinjsko posuđe i amfore, datiramo u razdoblje od početka 5. do 7. stoljeća.
The influence of mercury vapor on the electrical resistance of chalcogenide amorphous films
Authors: Rubish V.M. , Kyrylenko V.K. , Durkot M.O. , Boryk V.V. , Dzumedzey R.O. , Yurkin I.M. , Pop M.M. , Myslo Yu.M.
Published: June 2023

Using the planar structures "Ni layer - chalcogenide amorphous film - Ni layer" and "graphite probe - chalcogenide amorphous film graphite probe" samples, the influence of mercury vapor on the electrical resistance of amorphous films of the Se-Te, Se-Sb and Se-As systems was investigated. It was established that exposure of samples in mercury vapor leads to a decrease in their electrical resistance by 4-7 orders of magnitude. As the temperature and mercury concentration increase, the transition time from a high-resistance state to a low-resistance state decreases. When introducing Te, Sb, and As into amorphous selenium and increasing their concentration in the composition of the films, the transition time increases, and the value of the change in resistance decreases. It was established that the change in resistance is mainly determined by the change in surface conductivity of chalcogenide films. A decrease in the electrical resistance of selenium-containing amorphous films modified with mercury is caused by the formation of HgSe crystalline inclusions in their matrix.
The influence of the plates on the effectiveness of penetrating thermoelements in the cooling regime
Authors: Semeshkin V.A. , Cherkez R.G. , Zhukova A.S. , Stefiuk V.V.
Published: June 2023

This paper describes the physical model of the penetrating thermoelement with the developed surface of warmth exchange for the cooling of the air’s flow. It presents the theory of the calculation and the method of the computer modeling of the temperature’s and potential’s allocation, the definition of the effectiveness of the energy’s transformation – the cooling factor and the cooling efficiency. This work researches the 3D temperature’s and materials’ allocation for the material of the branches of the thermoelement based on Bi2Te3.
La península de Omán: sociedad y usos del entorno en los oasis de la antigua Magán
Authors: Cerro Linares C. del
Published: June 2023

Los oasis de la Península de Omán han sido testigos de la presencia de grupos humanos documentados desde al menos el III milenio a.C. Entre el gran desierto de Arabia y las costas del Golfo y el Índico, los oasis de al Ain-Buraimi y al Madam-Mleiha nos ofrecen una interesante información desde el III al I milenio a.C. sobre la variedad de las estructuras domésticas, alimentación, animales, usos agrícolas (como la aparición de los afl?j) y del entorno. La presencia de la misión arqueológica española de la Universidad Autónoma de Madrid en la antigua Magan nos permite además hacer un estudio del paisaje, la vegetación y los usos actuales de la tierra en este área.Palabras clave: Península de Omán, Emiratos Árabes Unidos, Magan, Oasis, falaj, Hili, al madam1-Thuqeibah, usos del entorno, textos sumerios.Abstract:The oases of the Oman Peninsula have witnessed the presence of human groups, documented, at least, from the third millennium B.C. Between the vast Arab desert and the coasts of the Gulf and the Indian Ocean, the oases of al Ain-Buraimi and al Madam-Mleiha offer us some very interesting information (from the third to the first millennium B.C.) about the variety of the household structures, food, animals, agricultural uses (such as the appearance of afl?j), and the surroundings. The presence of the Spanish Archaeological Mission from the Autónoma University in Ancient Magan enables us at the same time to carry out a study of the landscape, the vegetation and the current uses of the land in this area.Keywords: Oman Peninsula, United Arab Emirates, Magan, Oases, falaj, environment uses, Hili, al Madam1-Thuqeibah, Sumerian texts.
Henry Layard a Madrid: Il lavoro di un diplomatico
Authors: Escribano Martín Fernando
Published: June 2023

Layard es uno de los grandes pioneros del Orientalismo. Posteriormente a este trabajo diplomático y científico, desarrolló una interesante carrera política en su país y posteriormente como embajador en Madrid y Constantinopla. El presente trabajo pretende glosar su presencia en Madrid. En base a unas memorias sólo pergeñadas por parte del embajador Layard, podemos observar desde su perspectiva la política española en su periodo más convulso, cuando los gobiernos y regímenes cambiaban de signo en muy poco tiempo. Y se pretende también señalar la presencia del matrimonio en la vida social y cultural española, donde tomaron una relevancia significativa. La presencia de Layard en España no pasó inadvertida.Palabras clave: Layard, historia del orientalismo, siglo XIX español. Abstract:Layard is one of the great pioneers of Orientalism. Following this work diplomatic and scientist, developed an interesting political career in his country and later as ambassador to Madrid and Constantinople. This paper attempts to gloss its presence in Madrid. Based on a memoirs just started by the Ambassador, we can see from his perspective the more turbulent Spanish political period, when governments and regimes changed sign in no time. And it is also intended to signal the presence of the marriage in the Spanish cultural and social life, where they took a significant relevance. Layard’s presence did not go unnoticed in Spain.Keywords: Layard, Orientalism history, Spanish nineteenth century.
La "parole del re" nei testi giuridici e politici dell'Antico Regno: Alcuini aspetti del lessico e della fraseologia ittita
Authors: Dárdano Paola
Published: June 2023

Nel presente contributo si analizza la formula LUGAL-aš utt?r ‘parole del re, disposizioni del re’ nei testi giuridici di età antico-ittita. Il vocabolo uttar presenta un’ampia gamma di significati: ‘parola, discorso; cosa, affare; caso legale; motivo’. Nonostante l’etimologia di uttar sia controversa (sono stata proposte tre differenti etimologie indoeuropee), si esamina l’ipotesi che uttar sia un calco semantico dall’accadico aw?tum ‘parola; notizia, diceria; comando, disposizione; decisione; caso giuridico; affare, fatto’. Si analiza inoltre il rapporto con memiÔa(n)-: uttar e memiÔa(n)- sono in gran parte sinonimi, infatti entrambi possiedono i significati di ‘parola’, ‘azione’ e ‘affare, faccenda”. Mentre uttar è bene attestato in antico-ittito, memiÔa(n)- è documentato soprattutto nei testi medio-ittiti e nelle copie di età imperiale. Proprio in età imperiale memiÔa(n)- diventa più frequente rispetto a uttar, tanto da assumere gradualmente la funzione di quest’ultimo.Parole chiave: Lingua ittita, fraseologia ittita, antico ittita, contatto linguistico, calco semantico.AbstractThe present paper examines the formula LUGAL-aš utt?r ‘words of the king, i.e., orders of the king’ in the law texts of the Old Hittite period. In Hittite the word uttar presents a wide variety of meanings: ‘word, speech; thing; legal case; reason”. The etymological interpretation of uttar has proven to be very difficult:three different Indo-European etymologies have been proposed. The hypothesis is that Hitt. uttar is a semantic calque from Akkadian aw?tum ‘spoken word, utterance; news, report; command, order, decision; legal case; matter, affair, thing’. Moreover, the relations with the synonym memiÔa(n)- are investigated: memiÔa(n)- anduttar are largely synonymous, both possessing the three basic meanings ‘word’, ‘deed’, and ‘matter, affair’. Although uttar is well attested in Old Hittite, memiÔa(n)- first appears in Middle-Hittite texts and in New-Hittite copies of older texts. During the New-Hittite period memiÔa(n)- became more common than uttar and gradually assumed some of the latter’s usages.Keywords: Hittite language, Hittite phraseology, Old Hittite, language contact, semantic calque.
Scrivere di terremoti a Nuzi
Authors: Negri Scafa Paola
Published: June 2023

Il testo Nuziano SMN 3180 che tratta di terremoti, differenziandosi completamente dalla rimanente documentazione nuziana, è stato riconosciuto come un omen che faceva riferimento al testo dell’Enuma Anu Enlil, e che era stato redatto nel regno di Arrap?a. Nel presente lavoro vengono analizzate alcune differenze tra il testo di SMN 3180 e il resto del corpus: in particolare si fa un accurato riferimento ai nomi dei mesi, nel testo in questione e nel resto del corpus nuziano. Anche la struttura del documento viene presa in considerazione, nell’ottica di un possibile confronto con la ricca documentazione neo-assira. Quanto alla natura del testo, viene avanzata l’ipotesi che si tratti di un testo scolastico, anche se questa ipotesi non sembra molto convincente, e si è proposta anche una nuova possibile ipotesi. Non si è mancato di sottolineare quanto sia importante questa tavoletta per una più corretta definizione e descrizione del sistema scribale del regno di Arrap?a.Parole chiave: Terremoti, Testi di Nuzi, Responsi su omina Abstract:The Nuzi text SMN 3180 that is related to earthquakes, differs completely from the remaining Nuzidocuments. It has been recognized as an omen related to the text of the Enuma Anu Enlil, and had beendrafted into the realm of Arrapha.In this paper some differences between the text of SMN 3180 and the rest of the Nuzi corpus are analyzed:a particular attention is paid to the names of the months, in the text in question and in the rest of the Nuzicorpus. Even the structure of the document is taken into consideration, in view of a possible comparison withthe rich neo-Assyrian documentation.As to the nature of the text, it is suggested that it is a scholar text, but this hypothesis does not seem veryconvincing; a new possible hypotheses has been also proposed.It has been pointed out how important is this tablet for a more correct definition and description of thescribal system of the kingdom of Arrapha.Keywords: Earthquakes, Nuzi Texts, Reports on Omens