bluuebunny/crossref_metadata_2025 huggingface dataset:
What does mBERT layers encode from code-switched data?
Authors: Chakka Chaitanya , R Mithun Kumar S , Malapati Aruna
Published: December 2023

BERT is an encoder transformer model that generates contextual representation in English monolingual data. Multi-lingual BERT (mBERT) extends BERT's capability to more than 104 languages. The better performance in downstream NLP tasks by these models is attributed to the layered architecture. In monolingual data, embedding these layers encodes linguistic information helpful in numerous tasks like Parts of Speech (POS) tagging, Named Entity Recognition (NER), finding structural dependency, etc. We hypothesize that the hidden states contain a lot of valuable information, and investigating the effectiveness of using the pre-trained features extracted from different layers of the mBERT model would help us unravel more linguistic properties of code-switched data. We use probing tasks, which are auxiliary tasks that aid in isolating a linguistic property that helps understand the behavior of each layer within the model. We introduce a novel mechanism using five different probing tasks like gender, mood, number, person, and tense that help highlight and detect linguistic phenomena of interest. We then continue to use these datasets to determine what layers of mBERT are performing better for each task using MCC and F1 measure scores. We observe that the tasks that involved syntactic tasks are better performed at the layers below the 5th layer; as the tasks keep reduced in syntactic importance, the better-performing layers move towards the last layers, reinforcing the behavior seen when the same tests are performed in monolingual corpora.
Safety and Efficacy of of apatinib combined with chemotherapy in the second-line and subsequent lines of advanced gastric cancer: A systematic review and meta-analysis
Authors: Li Yuqi , Pan Di , Liu Haonan , Yao Zhiyuan , Wang Haiyan
Published: December 2023

Objective
A meta-analysis was performed to compare the efficacy and safety of apatinib combined with chemotherapy in the second-line and subsequent lines of advanced gastric cancer.
Methods
A computerized systematic search of databases such as PubMed, Embase, the Cochrane Library, CNKI, Wanfang Data, and VIP e-Journals was performed to find literature comparing apatinib combined with chemotherapy in the treatment of advanced gastric cancer.Literature search, quality assessment and data extraction were performed independently by two researchers. Stata 16 software was used to process and analyze the data. And, we assessed heterogeneity with I2 and p-value, and performed sensitivity analysis.
Results
A total of 1217 patients with advanced gastric cancer were included in 13 studies, including 652 patients in the apatinib combined with chemotherapy group and 565 in the chemotherapy group.Meta-analysis results showed that the objective response rate (ORR) of the observation group was better than that of the control group(0R = 2.49, 95% CI = 1.86–3.34), and the disease control rate (DCR) of the observation group was also better than that of the control group(OR = 2.78,95% CI = 2.11–3.66).The R0 resection rate was also statistically significant(OR = 2.31, 95% CI = 1.09–4.92).In addition, when comparing total adverse reactions (AEs) at any level, there was a statistical difference(OR = 1.61, 95%CI = 1.39–1.86).
Conclusion
Compared with the chemotherapy group, apatinib combined with chemotherapy has better efficacy and controllable safety in advanced gastric cancer.
Incidence and Predictors of Acute Kidney Injury among Patients Admitted to Adult Intensive Care Unit at West Amhara Comprehensive Specialized Hospitals, Northwest Ethiopia: A multicenter retrospective follow-up study
Authors: Beyene Meseret Mekuriaw , Azagew Abere Woretaw , Abetew Kennean Mekonnen , Alemu Gebrie Getu , Aynalem Zewdu Bishaw , Guadie Bazezew Asfaw
Published: December 2023

Introduction: Acute kidney injury (AKI) is a clinical syndrome characterized by a sudden decrease in or loss of kidney function. In Ethiopia, the morbidity and mortality associated with acute kidney injury is an important challenge for the health community and patients. However, there is limited evidence on the incidence and predictors of acute kidney injury among intensive care unit patients in Ethiopia.
Objective: To assess incidence and predictors of acute kidney injury among intensive care unit patients in West Amhara comprehensive specialized hospitals, Northwest Ethiopia, 2023.
Methods: A multicenter institution-based retrospective follow-up study was conducted from January 1, 2020-December 31, 2022 among intensive care unit patients admitted to West Amhara comprehensive specialized Hospitals, Northwest Ethiopia. A total of 628 patient charts were chosen using systematic random sampling. Data were collected using a checklist, entered using Epi-data 4.6, and exported to STATA version 14 software for data analysis. After the bivariable and multivariable Cox regression analysis, an Adjusted Hazard Ratio (AHR) with 95% confidence intervals (CI) at p-value of <0.05 was reported to declare the strength of association and statistical significance, respectively.
Result: The overall incidence rate of acute kidney injury was 19.67 per 1000 (95% CI: 15.76-24.56) person-day of observation with a median survival time of 17 days (IQR=11–35). Sepsis (AHR= 2.02: 95% CI: 1.06, 3.85), diabetes mellitus (AHR=2.46: 95% CI: 1.44, 4.22), congestive heart failure (AHR= 3.11: 95% CI: 1.57, 6.16), Anemia (AHR=3.28: 95% CI: 1.77, 6.09), Vasopressors (AHR=2.57: 95% CI: 1.35, 4.90), and thrombocytopenia (AHR= 2.18: 95% CI: 1.20, 3.96) were found to be significant predictors of acute kidney injury among patients admitted to ICU.
Conclusion and recommendation: The overall incidence rate of acute kidney injury among patients admitted to the intensive care unit was lower as compared to studies conducted in developed countries. Sepsis, diabetes mellitus, congestive heart failure, anemia, vasopressors and thrombocytopenia were predictors of acute kidney injury. Therefore, health care providers shall give special emphasis and close follow-up for those patients to reduce the risk of AKI.
Factors associated with low tuberculosis case detection and investigation in public health facilities (PHFs) in Uganda: A case study of Bududa district
Authors: Tumuhairwe Imelda , Komuhangi Alimah , Okello Alfred , Ayebale Apolo , Buyinza Ambrose Wabwire , Bwire Godfrey
Published: December 2023

Background
Although great strides have been made to control and cure tuberculosis (TB) globally, Uganda has a high burden with an annual incidence of 200/100,000 persons and a mortality rate of 35 per 100,000 persons. The extent to which patients with symptoms indicative of TB access care and receive TB testing at public health facilities (PHFs) in Bududa districts, eastern Uganda, and the factors associated with it are unknown. This study aimed to determine the proportion of patients with symptoms that might suggest TB and received care and TB testing at the PHFs in Bududa districts and to explore the factors that were associated with this proportion.
Methods
A cross-sectional study that employed both quantitative and qualitative data collection techniques was conducted in November 2019 on consenting respondents with symptoms that might suggest TB who sought care in PHFs in Bududa districts and key informants overseeing TB care in the district.
Findings:
A response rate of 97.6% (249/255) was recorded. Only 18.8% (46/256) of respondents who reported having symptoms suggestive of tuberculosis were investigated for TB. The majority of patients, 87.4% (214/245), never had sputum requested, and up to 91.7% (222/242) never had a chest X-ray (CXR) done. Participants who came through the outpatient department (OPD) were 12% less likely to be screened or investigated for TB than those coming through the ART clinic (PR = 0.88, 95% CI (0.79, 0.98). Patients who came from rural areas were 26% more likely to miss TB screening or investigation compared to those patients from urban areas (PR = 1.26, 95%CI (1.16, 1.38). Factors contributing to low TB detection rates were too much workload, lack of technical staff to carry out TB investigation and diagnosis, inadequate supplies and TB medicines, lack of equipment and unreliable electricity.
Conclusion
This study highlights the need for increased TB screening and investigation in PHFs in Bududa district, particularly in rural areas. To improve TB detection, investigation and diagnosis, the healthcare system invests in more technical staff, equipment, protective gear, and TB drugs. Additionally, the healthcare system should ensure that there is adequate reliable electricity to avoid equipment breakdowns.
Investigating Canadian Radiology Residents’ Personal Financial Literacy: A Nation-Wide Assessment.
Authors: Sharifabadi Anahita Dehmoobad , Bellini Jonathan , Alabousi Abdullah , Monteiro Sandra , Mensinkai Arun , Al-Arnawoot Basma
Published: December 2023

Introduction:Resident physicians throughout Canada carry large debt to finance their education. The literature suggests that debt and money management both play a large role in day-to-day life decisions and in deciding the future of physicians. The objective of this observational study is to assess the financial literacy of Canadian radiology residents through testing their financial knowledge and obtaining an understanding of their financial wellness.
Methods:A survey was designed to assess the financial literacy and current financial status of radiology residents. After a pilot run to ensure robustness, the survey was distributed nationally to Canadian radiology residents via Google Forms. Descriptive analyses on preliminary data and the association between level of training and financial quiz scores were obtained.
Results:In total, 104 valid responses from 16 universities were received. Respondents’ levels of training were spread across the 5 training levels. The majority (53%) of residents indicated that their debt was greater than $150,000, yet only 12% of residents stated they had a formal financial residency curriculum. The average score of residents on the financial literacy quiz was 71% and survey quiz scores were not associated with training level (p = 0.71). The majority (89%) of residents indicated a strong interest in a formal financial literacy curriculum, with 80% stating they would like the curriculum delivered by other physicians.
Conclusion:Our findings demonstrate unique insight into the financial literacy and demographics of Canadian radiology residents. Overall, residents face a high debt burden and the majority feel that they do not have an adequate financial literacy curriculum in their program. Current resident physicians value a formal financial literacy curriculum as a part of their residency program despite existing financial knowledge. Most importantly, residents feel that a curriculum created with involvement of other physicians would be optimal.
Prognostic nomogram of the young renal cell carcinoma patient: a SEER-based study
Authors: Huang Yanping , Chen Yonggui
Published: December 2023

Objective
We have constructed and verified nomograms to predict survival in young renal cancer survivors.
METHODS
We used the US SEER database to conduct a population-based cohort study. Patients diagnosed with young renal cancer were abstracted from the 2000–2018 Surveillance, Endemic Epidemiology, and End Results (SEER) data base, and variables were screened by both univariate and multivariate logistic regression analysis. Risk factors that were statistically meaningful were used to establish predictive models. The areas of the curve (AUC) of the working characteristics of the subjects were used to assess the models' performance.Accuracy and clinical usability were evaluated based on the results of ROC curve, C-index and DCA curve.
RESULTS
The training cohort in this study includes 3306 patients with a validation cohort of 1416 patients.Multifactorial analysis indicated that patients who were young, married, well-differentiated, low T, N, M stage, and surgery had improved prognosis. The nomogram included 12 independent factors affecting overall survival. The model had a c-index of 0.82, which represents predictive accuracy.The AUC values in the validation set were 0.91, 0.85 and 0.82 for 1, 3 and 5 years, depending on the type of the validation set.The model was shown to have high computational accuracy.The DCA results indicated that the model had a favorable net benefit for patients with renal cell carcinoma.
CONCLUSION
We have successfully structured the accurate and effective nomograms to predict the prognosis of young renal cancer patients, which helps physicians to choose individualized treatment strategies for young renal cancer patients.
Low sex hormone-binding globulin levels and reduced risk of chronic kidney disease in adults
Authors: Wang Lingling , Chen Jianlan , Li Changhao , Xin Xiaoqin
Published: December 2023

Investigation on the association between serum sex hormone-binding globulin (SHBG) and chronic kidney injury are few. However, the evidence supporting this finding is limited and controversial. The purpose of this study was to estimate the effects SHBG had on chronic kidney disease (CKD). A total of 8,742 adults from the National Health and Nutrition Examination Survey (NHANES) (2013–2016) were selected in the present study. CKD was viewed as estimated glomerular filtration rate (eGFR) < 60 ml/min per 1.73 m2 or urine albumin to creatinine ratio (UACR) ≥ 30 mg/g.A significant association between SHBG (log2 transform) and the prevalence of CKD was observed based on a full adjustment model (OR 1.04; 95% CI 1. 14- 1.49). For ensuring the robustness of the results, the analysis of subgroups stratified by gender and age, and the results were still stable in a series of sensitive analysis (p for trend < 0.05). Significant correlations were observed of serum SHBG with kidney impairment among both males and females. Causation and potential mechanisms should be further investigated in future prospective cohort studies and basic researches.
Description of the attitudes of the surgical team toward the implementation of robotic surgery in the Tunisian public health institution
Authors: Belgacem Amina , Sebri Ameni , Bekalti Wiem , Chouari Monia , Chrif Taieb , Soussi Sonia
Published: December 2023

Introduction The introduction of robotic surgery is a major advance for this decade. The implementation of this technology determines the future of this potential progress in Tunisian hospitals. The purpose of this study was to describe the attitudes towards the implementation of robotic surgery among the surgical team in the Tunisian public health institution. Materials and methods It was a quantitative descriptive study conducted in 2023 in the Tunisian public health institution. The study sample consisted of 46 professionals from the carcinology operating theatre. We used a valid and reliable questionnaire with satisfactory psychomotor characteristics. The original English version of the questionnaire was emailed to us by the corresponding author McBride KE with authorisation the measuring instrument. The interpretation of the results was based on the “Health Technology Acceptance Model”. Results More than half of our population had positive attitudes about the benefits of robotics in patient care: (78.3%) agreed that robotic surgery will improve the quality of surgical care and that after initial training robotic surgery will reduce operating time (76.1%). (97.8%) liked learning the new skills required to use the robot. Concerns were a little high. :(65.2%) of the respondents said that they were involved in the care and handling of the robot and its surgical equipment and that they had little opportunity to take part in the surgical programme. Our study identified key factors for the successful implementation of robotic surgery: communication (93.5%), responsibility (91.3%), and theoretical and practical training (87%). Conclusion Robotic surgery is a technology that is transforming the field of health, in the modernisation of health establishments.
Analytical study of the propagation of nonlinear waves on a Murnaghan hyperelastic circular pipe
Authors: Althobaiti Saad
Published: December 2023

The propagation of waves on nonlinear structures is a vital feature that plays a significant part in elastodynamics. Thus, the current study makes use of some powerful analytical approaches to examine the propagation of nonlinear elastic waves on a Murnaghan hyperelastic circular pipe. Indeed, the admittance of double dispersion terms coupled with the presence of material nonlinearity in the governing nonlinear mode is what makes the study superb. Therefore, some interesting exact analytical solutions are constructed and further analyzed with regard to the parameters that characterize the propagation. In the end, some graphical depictions of some of the gained solutions are supplied to for clarification.
A recurrence prognosis model of colorectal cancer based on preoperative nutritional score and clinical features
Authors: 东 哥哥 , Huang Mingliang , Xu Heyang , Zeng Yujie , Lan Qiusheng , Liu Lu , Chu Zhonghua , Lai Wei
Published: December 2023

Objective:
To analyze the relationship between preoperative NRS2002 score, COUNT score, and clinical tumor characteristics with postoperative recurrence in patients with stage I-III colorectal cancer. To establish a prediction model using Lasso-Cox regression and visualize the model using a nomogram.
Methods:
A retrospective study was conducted on 235 patients with stage I-III colorectal cancer who underwent radical resection at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, from January 2018 to July 2019. Lasso-Cox regression identified risk factors for tumor recurrence, and the results were used to establish a Cox proportional hazards regression model. The model was visualized using a nomogram. Bootstrap resampling was employed to internally validate the model.
Results:
The Cox model included BMI, preoperative intestinal obstruction, neural invasion, tumor differentiation, serum albumin, total lymphocyte count, and pN stage, which were selected using Lasso regression. The C-index for 1-year DFS was 0.8 (95% CI: 0.77–0.84), for 2-year DFS was 0.8 (95% CI: 0.78–0.83), and for 3-year DFS was 0.78 (95% CI: 0.75–0.80). The ROC curve of the model had an AUC of 0.82 (95% CI: 0.78–0.86) for 1-year DFS, 0.82 (95% CI: 0.80–0.85) for 2-year DFS, and 0.80 (95% CI: 0.76–0.83) for 3-year DFS, indicating good discriminative ability. Bootstrap resampling was used for model calibration, and the calibration curves for 1-year DFS, 2-year DFS, and 3-year DFS showed good fit with the standard curve, indicating good calibration of the model. Decision curve analysis (DCA) showed that the model had better clinical applicability compared to TNM staging. Finally, a nomogram was constructed to visualize the results.
Conclusion:
The nomogram prediction model, derived from Lasso-Cox regression, integrates preoperative nutritional and immune status, tumor pathological characteristics, and clinical symptoms. It demonstrates greater clinical utility than TNM staging in identifying high-risk patients for postoperative recurrence. The nomogram offers guidance for screening and developing personalized follow-up strategies or treatment plans for patients with predicted recurrence risk, aiming to enhance long-term prognosis.
Polyvascular Atherosclerosis and Renal Dysfunction Increase the Odds of Cognitive Impairment in Vascular Disease: Findings of the LipidCardio Study
Authors: König Maximilian , Palmer Katie , Steinhagen-Thiessen Elisabeth , Demuth Ilja
Published: December 2023

Introduction: Growing evidence suggests a causal role for atherosclerotic vascular disease in cognitive impairment and dementia. Atherosclerosis may present as monovascular disease (monoVD) or as widespread polyvascular atherosclerotic disease polyVD). Evidence on the relationship between monoVD or polyVD and cognitive impairment is limited.
Methods: We conducted a cross-sectional analysis of baseline data from the LipidCardio Study. The main outcome measure was the presence of cognitive impairment, defined as a Mini-Mental State Examination (MMSE) score < 26.
Results: The mean age was 71.5 years, 30.3% were female, 17.3% had no evidence of large-vessel atherosclerosis, 71.1% had monoVD, and 11.7% had polyVD, defined as the presence of atherosclerosis in ≥2 vascular territories (coronary, cerebral, aortic, or lower extremity). A total of 21.6% had cognitive impairment according to the prespecified cutoff (MMSE < 26). Overall, the odds of cognitive impairment increased for each additional vascular territory affected by atherosclerosis (adjusted odds ratio 1.76, 95% confidence interval (CI) 1.21-2.57, p = 0.003). Furthermore, there is evidence for an interaction between vascular disease and chronic kidney disease (CKD). The odds of cognitive impairment were not greater in the monoVD subgroup than in the no atherosclerosis subgroup (OR 1.05, 95% CI 0.50-2.19; p = 0.906), while the odds ratio (OR) of cognitive impairment with polyVD compared to no atherosclerosis was 3.15 (95% CI 1.24-8.00; p = 0.015). In contrast, in patients with CKD, both monoVD and polyVD were associated with significantly greater odds of cognitive impairment than was no atherosclerosis.
Conclusions: PolyVD is associated with increased odds of cognitive impairment. MonoVD is associated with cognitive impairment only in the presence of CKD.
Synergistic effects of elevated temperature with pesticides on reproduction, development and survival of dung beetles
Authors: Esquivel-R Andrea , Baena-Díaz Fernanda , Bustos-Segura Carlos , De Gasperin Ornela , González-Tokman Daniel
Published: December 2023

In times of global change, high temperatures can potentiate the negative effects of pesticides and other stressors. Here, we evaluated under controlled laboratory conditions the effect of a moderate increase in temperature in combination with ivermectin (an antiparasitic drug used in cattle that is excreted in dung), an herbicide, and parasitic pressure, on the reproductive success, development time and adult survival of dung beetles Euoniticellus intermedius, which are naturally exposed to these stressors. We found that heat increased the number and proportion of emerged offspring, but in combination with ivermectin, herbicide and parasitic treatments, it had synergistic negative effects. Moreover, heat in combination with ivermectin and with parasitism caused a synergistic increase of adult offspring mortality and, in combination with the herbicide, heat synergistically accelerated development. Our results indicate that heat can enhance the negative effect of other stressors and act synergistically with them, harming dung beetles, a group with important ecological and economic value in natural and productive ecosystems. Although adult sex ratio was not affected by experimental treatments, contrasting responses were found between males and females, supporting the idea that both sexes use different physiological mechanisms to cope with the same environmental challenges. The effects that combined stressors have on insects deepen our understanding of why we are losing beneficial species and their functions in times of drastic environmental change.
Assessment of two steroid hormones Progestin and estrogen on cellular model Paramecium: oxidative stress, Mitochondrial swelling and kinetic.
Authors: Zouaoui Sara , Rouabhi Rachid , Bouzenzana Sara , Menaceur Fouad , Gasmi Salim , Benaicha Brahim
Published: December 2023

Synthetic steroids like progestin and estrogen, which are frequently present in contraceptive pills, alter behavior, physiology, and biochemistry in life beings. Although, the harmful effects of neosynthesized products are widely researched, there are no reports on their individual or mixture uses. Therefore, this study is to evaluate the effects of each component alone and in combination on Paramecia, a freshwater protozoan, at low relevant ambient concentrations in a ratio that is comparable to that of most recommended by doctors. The cells kinetics test was used to evaluate the acute toxicity of these two steroids, individually and their mixture after 24 and 48 hours. Furthermore, the consequences of oxidative stress were investigated over a duration of 120 hours. While the mixture largely impeded motility, immobility was concentration-dependent, Progestin is less impacts than Estrogen. Oxidative stress responses demonstrated a substantial drop in GSH contents and SOD, CAT activity, as well as an increase in MDA levels and GST activity in treated groups relative to the control (p < 0.01). These results imply that while these two steroids caused a generation of reactive oxygen species (ROS) in Paramecium, this result was confirmed by the mitochondrial assessments respiration and swelling that explain the amount of cellular number reduction.
Mut zu offenen Lernumgebungen – ein Modell zur Gestaltung von nachhaltigen Lernprozessen
Authors: Albert Sabine , Purgaj Jure
Published: December 2023

Um Studierende der Berufsbildung auf die Berufswelt mit komplexen und unbekannten Anforderungen vorzubereiten, braucht es Lernumgebungen und Lernprozesse, die den Erwerb von Future Skills nachhaltig fördern. Das erfordert eine mutige Haltung der Lehrenden sowie geeignete hochschuldidaktische Formen. Das SAJP-Modell (Akronym: Sabine Albert, Jure Purgaj) zeigt fünf Entwürfe zur Generierung von Umgebungen, in denen Lernprozesse ermöglicht werden. Des Weiteren werden in diesem Artikel die Lernprozesse dargestellt und mit Beispielen illustriert. Der persönliche Bezug zum Fachgebiet und individualisierte Lernstrategien führen zu selbstgesteuerter Gestaltung der Lernumgebung, Verantwortung für die Lernprozesse und dazu, in der Arbeitswelt agil zu agieren.
A simple method for obtaining heat capacity coefficients of minerals
Authors: Bowman Samuel , Pathak Arkajyoti , Agrawal Vikas , Sharma Shikha
Published: December 2023

Heat capacity data are unavailable or incomplete for many minerals at geologically relevant temperatures. Despite the availability of entropy and enthalpy values in numerous thermodynamic tables (even sometimes at elevated temperatures), there remains need for extrapolation beyond, or interpolation between, temperatures. This approach inevitably results in estimates for entropy and enthalpy values because the heat capacity coefficients required for optimal thermodynamic treatment are less frequently available. Here we propose a simple method for obtaining heat capacity coefficients of minerals. This method requires only the empirically measured temperature-specific heat capacity for calculation via a matrix algorithm. The system of equations solver is written in the Python computing language and has been made accessible in an online repository. Thermodynamically, the solution to a system of equations represents the heat capacity coefficients that satisfy the mineral-specific polynomial. Direct coefficient calculation will result in more robust thermodynamic data, which are not subject to fitting uncertainties. Using hematite as an example, this method provides results that are comparable to conventional means and is applicable to any solid material. Coefficients vary within the traditional large 950 K temperature interval, indicating that best results should instead utilize a smaller 400 K temperature interval. Examples of large-scale implications include the refinement of geothermal gradient estimation in rapidly subsiding sedimentary basins or metamorphic and hydrothermal evolution.
PELATIHAN KULTUR JARINGAN TUMBUHAN BAGI SISWA SMA NEGERI 7 YOGYAKARTA
Authors: None Ratih Restiani , Ariestanti Catarina Aprilia , Purba Laurentia Henrieta Permita Sari , Retnowati Theresia Sri , Matheos Josiah Herald , Kaban Sarah Mega Pratenna , Sekar Astrid Ayu
Published: December 2023

Kultur jaringan tumbuhan merupakan salah satu topik dalam modul Bioteknologi pada mata pelajaran Biologi kelas XII Sekolah Menengah Atas. Topik ini belum opimal diberikan di sekolah khusunya di SMA Negeri 7 Yogyakarta karena keterbatasan SDM yang berpengalaman di bidang kultur jaringan tumbuhan dan belum tersedianya fasilitas dan peralatan yang mendukung pelaksanaan praktikum topik tersebut. Oleh karena itu, kegiatan ini bertujuan untuk untuk membantu siswa dalam memperoleh pengetahuan dan keterampilan mengenai prinsip dasar, manfaat, dan tahapan kerja kultur jaringan tumbuhan. Selain itu kegiatan ini diharapkan dapat bermanfaat dalam membantu tercapainya kompetensi dasar pengetahuan dan keterampilan dalam modul Bioteknologi mata pelajaran Biologi Kelas XII. Pelatihan dilaksanakan di laboratorium Bologi SMA Negeri 7 Yogyakarta diikuti oleh 10 orang siswa kelas XII anggota kelompok Karya Ilmiah Remaja (KIR). Tahap pelatihan  meliputi tanya jawab sebelum materi, pemaparan materi, pelaksanaan praktikum, tanya jawab setelah praktikum, dan evaluasi. Materi diberikan menggunakan metode ceramah dan diskusi interaktif, dilanjutkan kegiatan praktikum meliputi pembuatan media kultur, sterilisasi dan inokulasi eksplan serta aklimatisasi yang dilaksanakan melibatkan partisipasi aktif masing-masing siswa. Hasil yang diperoleh dalam pelatihan ini adalah siswa mampu memahami dan melaksanakan kegaitan praktikum kultur jaringan tumbuhan dengan baik.
Utilização de software para o monitoramento de internações em pronto-socorro: Estudo-piloto
Authors: Rocha Hertaline Menezes do Nascimento , Trindade Mônica Viviany Silveira , Nascimento Nicoly Gabrielly Brito , Santos Thaiane Santana , Jesus Aryel Andrade de , Farre Anny Giselly Milhome da Costa , De Santana Filho Valter Joviniano
Published: December 2023

Objetivo: realizar o monitoramento das internações no pronto-socorro de um Hospital Universitário utilizando o Sistema de Informação e Monitoramento das Internações no Pronto-Socorro (Simips) que foi criado com o objetivo de monitorar as internações no PS e gerar informações que auxiliem na prática assistencial e na gestão de leitos, da qualidade da assistência e de riscos assistenciais. Método: trata-se de estudo-piloto que monitorou as internações de pacientes adultos em PS, da admissão em regime de internação até a saída, utilizando o Simips. A amostra foi composta por prontuários de pacientes adultos admitidos em regime de internação no PS durante os meses de junho a agosto de 2019. Foram coletados dados socioepidemiológicos, escore de gravidade, escore de dependência dos cuidados de enfermagem, escore News, ocorrência de eventos adversos, tempos de permanência e os desfechos de saída. Resultados: foram analisados 158 prontuários de pacientes com mediana de 65 anos de idade. No grau de dependência dos cuidados de enfermagem, 89% foram classificados como cuidados mínimos no primeiro dia de internação hospitalar. A frequência de eventos adversos foi 39,2% e o atraso na terapêutica (administração) medicamentosa (12%) e a ausência de conciliação medicamentosa (8,9%) foram os mais prevalentes. Conclusão: o estudo mostrou um tempo de permanência no alto de pacientes em regime de internação no PS, com predominância de pacientes idosos e uma alta incidência de eventos adversos.
 
desfecho, de forma clara, rápida e acessível, mostrou-se importante ao apontar situações que necessitam de intervenção imediata para melhorar a qualidade e segurança da assistência.
Estratégias desenvolvidas na atenção à saúde da população trans: Uma revisão de escopo
Authors: Félix Thallys Rodrigues , Rodrigues Maria de Lara Araújo , Figueiredo Rodrigo Silveira Tosta , Loyola Adriano Mota , Ferreira Junior Sérgio , Herval Álex Moreira , Bulgareli Jaqueline Vilela
Published: December 2023

Trata-se de uma revisão de escopo desenvolvida com o objetivo de mapear e sintetizar as estratégias desenvolvidas na atenção à saúde da população trans. A pesquisa foi realizada seguindo as recomendações do “Prisma Extension for Scoping Reviews” e incluiu artigos que discutissem abordagens, estratégias, dispositivos e ferramentas desenvolvidos para a atenção à saúde da população trans, considerando o enfrentamento às dificuldades e particularidades na perspectiva dos profissionais e a problemática da relação profissional-paciente no contexto do atendimento a este público. A coleta dos dados foi realizada em seis bases de dados em junho de 2021 abrangendo artigos, dissertações e teses. A amostra final foi composta por 15 artigos publicados entre os anos de 2008 e 2021. As estratégias publicadas eram diversas quanto a sua metodologia e contexto de desenvolvimento, e foram apresentadas em duas categorias: estratégias educacionais/formativas e estratégias institucionais/organizacionais. Concluiu-se que as estratégias existentes se constituem, principalmente, de abordagens educacionais voltadas para a conscientização dos profissionais de saúde em relação às necessidades específicas e disparidades que envolvem as pessoas trans, sendo estas práticas consideradas eficazes e necessárias.
éxito de los empresarios agrícolas y de sus haciendas en Ciudad Victoria de Tamaulipas (1899-1907)
Authors: Rodríguez Sánchez Jaime Alberto , Flores Méndez Yessenia
Published: December 2023

En este artículo se estudia a un grupo de empresarios agrícolas y sus haciendas en la capital de Tamaulipas (México), a través de los enfoques metodológicos de la investigación histórica. Éstos son el cuantitativo, el cualitativo y el comparativo, usados por algunos historiadores en el proceso de investigación. Mediante dichos métodos se obtuvo la tasa de crecimiento de cada una de una de las haciendas con base en la información numérica que se investigó principalmente en el Archivo General del Estado de Tamaulipas. Del gran universo de haciendas tamaulipecas, sólo se tomó una pequeña muestra de ellas para explicar a grandes rasgos el proceso del éxito de éstas y sus propietarios que eran considerados empresarios agrícolas. La investigación se basa en la utilización de nuevas fuentes documentales, con una preocupación por lo teórico y lo metodológico, para prestar mayor atención a los estudios de empresarios en la región tamaulipeca, y revela el éxito de los empresarios agrícolas porfiristas. A través del estudio de caso se aportan nuevos conocimientos a la historia económica en Tamaulipas.
Estudios Biológicos del Erizo Loxechinus albus, (Molina) (Echinoidea Echinodermata).
Authors: Buckle F. , Guisado CH. , Tarifeño E. , Zuleta A. , Cordova L. , Serrano C. , Maldonado R.
Published: December 2023

La acuicultura, que se ha desarrollado en muchos países del mundo ha adquirido en estos últimos años una importancia relevante. Esto lo confirman los diversos programas nacionales y regionales que sustenta FAO en Ecuador, Irán, Nepal, Túnez, Tailandiay otros (FAO 1971). Por lo general estos proyectos que son de alto costo, dedican su inversión a la piscicultura; sin embargo la Equinicultura (cultivo de erizos) ha tenido sólo en Japón la atención requerida. Tal es asi, que las investigaciones realizadas en ese país como también la organización y planificación de la explotación, permiten a través de cooperativas, mantener este importante rubro a un nivel de producción elevado. Como la disponibilidad natural de este recurso es insuficiente para la demanda del mercado, Japón importa grandes cantidades de gónadas de erizos semielaboradas. Este déficit en la oferta ha sido aminorado con importaciones desde Méjico, Taiwan, Corea, China y últimamente de Chile.
Antecedentes sobre la Biología y Tecnología del cultivo de Aulacomya ater (Molina, 1782) (Mollusca: Mytilidae)
Authors: Cancino Juan , Becerra Raúl
Published: December 2023

El presente trabajo recopila y analiza la literatura relacionada con la biología y cultivo en masa de la “cholga” Aulacomya ater (Molina, 1782) en Chile.La información sobre bancos naturales de la especie proviene, en su mayoría, del extremo sur de Chile. Estos se encuentran generalmente entre 0 y 20 metros de profundidad, asociados a fondos rocosos con pendiente fuerte. Un análisis de los datos pertinentes no muestra diferencias significativas en densidad de animales entre distintos tipos de sustratos.
The Collapse of an American Sustained Cultural Identity The American Civil Religion and the Spectre of Trumpism
Authors: Castilho Maria Teresa
Published: December 2023

This text stresses the diabolic spectreof Trumpism, a set of mechanisms for autocracy and authoritarianism, to redefine the United States while Trump’s supporters perceive America as a nation and an idea that have forgotten and betrayed them. Consequently, they deny the “religious” and mythical founding principles of the nation defending a “new religion”. Trump, the high priest of this “newreligion”, and Trumpism represent a crisis of faith around the so-called American civil religion and announce the possible final collapse of an imagined American sustained cultural identity
El concepto de microsoberanía y su importancia para la soberanía estatal
Authors: Spencer David Elliott
Published: December 2023

Las microsoberanías han adquirido una importancia creciente para los Estados que buscan fortalecer su control territorial. Las microsoberanías pueden tener un impacto desproporcionado con relación a su tamaño y el número de habitantes que las apoyan. En este artículo, se ofrece una definición del concepto de microsoberanías y se proporcionan criterios para identificarlas y evaluarlas cualitativamente. Se muestra que, además de ser un desafío para la soberanía de las naciones, también representan una oportunidad, sobre todo en regímenes democráticos, para fortalecer la soberanía a través de redes de poder en que se coopere con las microsoberanías, teniendo en cuenta las fortalezas de estas en autoridad moral y vínculo con la población.
La violencia política tras la independencia en el pensamiento de Lucas Alamán, José María Luis Mora, Juan B. Alberdi y Domingo F. Sarmiento
Authors: Hodge-Dupré Eduardo Andrés
Published: December 2023

Este trabajo aborda el tema de la violencia política tras el proceso independentista en el pensamiento de los mexicanos Lucas Alamán y José María Luis Mora, y de los argentinos Juan Bautista Alberdi y Domingo Faustino Sarmiento. Durante la primera mitad del siglo XIX, reflexionaron sobre la compleja situación de sus naciones, sumidas en la inestabilidad y la violencia por los conflictos y odios surgidos entre facciones tras la independencia. A partir de sus principales obras, se analizan las causas de dicha violencia, sus características y las consecuencias que ellos veían para el orden y el progreso de las nuevas repúblicas. En general, desde sus distintas perspectivas ideológicas, más liberales o más conservadoras, los cuatro coinciden en su preocupación por la violencia y en su ambivalencia sobre la influencia de la Revolución francesa en las naciones hispanoamericanas.
Manifestations and Outcomes of Intracerebral Hemorrhage During the COVID-19 Pandemic in China: Multicenter, Longitudinal Cohort Study
Authors: Wan Yan , He Quan Wei , Chen Shaoli , Li Man , Xia Yuanpeng , Zhang Lei , Sun Zhou , Chen Xiaolu , Wang David , Chang Jiang , Hu Bo
Published: December 2023

Background

The COVID-19 pandemic has inevitably affected the distribution of medical resources, and epidemic lockdowns have had a significant impact on the nursing and treatment of patients with other acute diseases, including intracerebral hemorrhage (ICH).

Objective

This study aimed to investigate how the COVID-19 pandemic affected the manifestations and outcomes of patients with ICH.

Methods

Patients with acute ICH before (December 1, 2018-November 30, 2019) and during (December 1, 2019-November 30, 2020) the COVID-19 pandemic at 31 centers in China from the Chinese Cerebral Hemorrhage: Mechanism and Intervention (CHEERY) study were entered into the analysis. Demographic information and clinical manifestations and outcomes were collected and compared between the 2 groups.

Results

From December 1, 2018, to November 30, 2020, a total of 3460 patients with ICH from the CHEERY study were enrolled and eventually analyzed. The results showed that during the COVID-19 pandemic, patients with ICH were more likely to be older (P<.001) with a history of ischemic stroke (P=.04), shorter time from onset to admission (P<.001), higher blood pressure (P<.001), higher fasting blood glucose (P=.003), larger hematoma volume (P<.001), and more common deep ICH (P=.01) and intraventricular hemorrhage (P=.02). These patients required more intensive care unit treatment (P<.001) and preferred to go to the hospital directly rather than call an ambulance (P<.001). In addition, the COVID-19 pandemic was associated with an increased risk of pulmonary infection during hospitalization (adjusted risk ratio [RRadjusted] 1.267, 95% CI 1.065-1.509), lower probability of a 3-month good outcome (RRadjusted 0.975, 95% CI 0.956-0.995), and a higher probability of in-hospital (RRadjusted 3.103, 95% CI 2.156-4.465), 1-month (RRadjusted 1.064, 95% CI 1.042-1.087), and 3-month (RRadjusted 1.069, 95% CI 1.045-1.093) mortality.

Conclusions

Our study indicated that the cloud of COVID-19 has adversely impacted the presentation and outcomes of ICH. Medical workers may pay more attention to patients with ICH, while the public should pay more attention to hypertension control and ICH prevention.

Trial Registration

Chinese Clinical Trial Registry ChiCTR1900020872; https://www.chictr.org.cn/showprojEN.html?proj=33817
Geographic Disparities in Access to Assisted Reproductive Technology Centers in China: Spatial-Statistical Study (Preprint)
Authors: Zhou Qingqing , Zeng Huatang , Wu Liqun , Diao Kaichuan , He Rongxin , Zhu Bin
Published: December 2023

UNSTRUCTURED

A study on infertility in China found that while 543 health care institutions are approved for assisted reproductive technology (ART), only 10.1% offer all ART services, with a significant skew toward the eastern regions, highlighting the accessibility challenges faced by rural and remote populations; this study recommends government measures including travel subsidies and education initiatives to improve ART access for economically disadvantaged individuals.
La crisis global del 2008: elementos para una cartografía del desastre
Authors: Álvarez Vázquez Gustavo
Published: December 2023

En el presente ensayo se utiliza a la cartografía como metáfora analítica para proponer una acercamiento a la complejidad de la crisis económica actual, presentando algunos de los factores que abren la posibilidad de realizar un diagnóstico más acorde con los alcances que dicha crisis posee.
Entre parroquias, misiones y territorios de conversión: la visita pastoral de Francisco Aguiar y Seijas a Querétaro y Sierra Gorda (1685-1686)
Authors: Bravo Rubio Berenise
Published: December 2023

Este artículo pretende poner en relieve las diversas realidades religiosas y eclesiásticas que a su paso descubrió el arzobispo de México, Francisco Aguiar y Seijas, durante la visita pastoral que realizó por 34 curatos ubicados entre la Sierra Gorda y la ciudad de Querétaro de noviembre de 1685 a abril de 1686. A partir del análisis del estado de la fábrica material de cada iglesia y de la cuantificación de fieles, eclesiásticos y cofradías que el prelado visitó, sostenemos que la ciudad de Querétaro fue la frontera de la Iglesia diocesana, ajena a los peligros de los “salvajes chichimecas” que asolaban las misiones como Xiliapa, Jalpan y Concá. Para demostrar lo anterior se analizó el libro de visita a Querétaro, que recién fue localizado en el Archivo General de la Nación (AGN) en México. En este artículo explicamos también cuáles fueron los dispositivos que el arzobispo articuló para lograr el avance de la jurisdicción episcopal y de la evangelización en esta zona.
“No sólo en jacales”: formas de habitar de las comunidades indias de la ciudad de México (1790-1813)
Authors: Quiroz Muñoz Enriqueta
Published: December 2023

El artículo se propone identificar los espacios vecinales ocupados por indígenas dentro de la ciudad de México a fines del periodo colonial. El argumento central es que dentro de los barrios de indios ya era posible visualizar transformaciones constructivas en sus formas de habitar, lo que sería hipotéticamente un signo de resiliencia y de acuerdos entre comerciantes, cofradías y conventos de instalar construcciones sólidas, multifamiliares y accesorias dentro de un suelo tradicionalmente indio, libre de tasaciones o impuestos por lo menos hasta 1812. La metodología empleada fue mapear la localización de barrios y de sus tipos de vivienda principalmente a partir de la información de padrones de propietarios y de tributarios, comparados en diferentes años: 1790, 1800, 1807 y 1813. El resultado fue la diferenciación entre los barrios de indios, donde sobresalen los del sureste, con un mayor apego a formas tradicionales de vida.
La complexión de los indios de Nueva España: composición, naturaleza y racialización en la Modernidad temprana (siglos XVI-XVII)
Authors: Vera Castañeda Julio
Published: December 2023

Este artículo discute el rol de la composición de la naturaleza americana en la racialización de los habitantes de Nueva España durante la primera Modernidad. A partir de un conjunto de historias naturales producidas entre 1577 y 1618, se plantea que el uso retórico de la teoría de los humores en la descripción de la complexión de los indios evidencia la condición política del concepto de naturaleza. A lo largo del escrito se da cuenta del modo en que los actores utilizan la tradición epistemológica de las “naturalezas locales” para inferiorizar la condición “natural” de los indios respecto de otros habitantes del territorio como los criollos y los españoles, y construir así una alteridad comprendida como natural. De este análisis se concluye que la inestabilidad del concepto de naturaleza y su inherente dimensión normativa contribuyen a la comprensión política del racismo durante la primera Modernidad y sus particularidades en el caso novohispano.
Sobre Christina H. Lee y Ricardo Padrón, eds., The Spanish Pacific, 1521-1815. A Reader of Primary Sources
Authors: Pinzón Ríos Guadalupe
Published: December 2023

Reseña del libro de Christina H. Lee y Ricardo Padrón, eds., The Spanish Pacific, 1521-1815. A Reader of Primary Sources (Ámsterdam: Amsterdam University Press, 2020), 249 pp.