bluuebunny/crossref_metadata_2025 huggingface dataset:
GLOBAL TRANSFORMATIONS: DIALECTICS OF CONTINUITY OF THE DISTANT PAST AND DENIAL OF THE RECENT
Authors:   Higher School of Economics, EVSTAFIEV D.G. ,   People’s Friendship University of Russia
Published: April 2024

Current global transformations are characterized not just by a complex change in the balance of power in world politics and economics, but also by at least a partial change in the architecture and organizational framework of political and economic relations at the global and regional levels. This is partly due to the fact that, due to objective and subjective reasons, it was not possible to launch the mechanism of “contractual” and evolutionary dismantling of geo-economic American-centricity, as a result of which these processes began to have not just a political, but a military-force character. The main question, however, is to what extent, within the current cycle of transformations at the global level, it will be possible to preserve those supra-spatial systems that, being fundamentally American-centric, ensured the American-centricity of the latest version of globalization as a whole. A curious dialectic of the development of current global transformations arises, saying that one of their most important features, if not the dominant ones, is a “rollback” to development paradigms characteristic of earlier historical (socio-historical and cultural-historical) eras, which actually means from a conceptual point of view, a break in the connection of not only cultural and political, but also economic modernity with postmodernity, which is now dominant in the world of the collective West. This predetermines the revolutionary nature of changes in the organization of political and economic relations, in particular the possibility of breaking existing relations of economic interdependence, as well as the fundamental impossibility of returning to the situation of the early 2020s, even if unfavorable for countries with anti-Western positions, especially Russia and China, the development of military-political processes.
SOCIO-ECONOMIC POLICY IN POST-SOVIET RUSSIA: STRATEGIC PRIORITIES AND POLITICAL MECHANISMS OF IMPLEMENTATION
Authors:   Central Russian Institute of Management, Branch of RANEPA, LEONOVA O.V.
Published: April 2024

In the context of modernization practices of Russian society and growing demands on human capital, socio-economic policy acts as an integral tool for the development and transformation of the state. The purpose of the article is to analyze the political mechanisms and strategic priorities for the implementation of socio-economic policy. The research uses methods of analysis, comparison and description, grouping, modeling, structural-functional, comparative-legal and factual analysis, and the method of expert assessments. The principles of a systematic and comprehensive study of socio-economic phenomena and processes, recognition of man as an actor (agent) in the development of society and its main value were also applied. The basis of the research is the concepts of the social state (welfare state), spatial development, human capital, and social justice. The article focuses on the political mechanisms for implementing the EPA and the results of its implementation at the federal and regional levels. The author comes to the conclusion that in conditions of geopolitical turbulence and modernization of various spheres of life, active socio-economic policy becomes a kind of effective core of state regulation, an instrument of transition to an innovative-reproductive type of development. As a result, the value and state identification components of the EPA are highlighted. A decision-making model based on historical experience and criteria-based assessment of socio-economic development should serve as a trigger for the timely development (adjustment) of strategic goals (national priorities).
AMPLIFICADOR DE ÁUDIO EDUCATIVO PARA A DEMONSTRAÇÃO DO EFEITO TERMIÔNICO
Authors: Machado Pedro Paulo da Cunha , Costa Ana Clara de Moura , Silva Guilherme Matheus Frade da , Lopes João Pedro Vieira , Nascimento Lorena Almeida do
Published: April 2024

As válvulas são dispositivos que utilizam o efeito termiônico para projetos de equipamentos eletrônicos. Foi a tecnologia dominante do início até meados do século XX, mas ainda são empregadas atualmente em equipamentos específicos como amplificadores de áudio. A invenção das válvulas eletrônicas promoveu um grande avanço da engenharia eletrônica, pois viabilizaram as tecnologias de comunicação, como os primeiros rádios, televisores e o desenvolvimento do primeiro computador eletrônico o ENIAC (Electronic Numerical Integrator Analyzer and Computer) em 1946. Nas últimas décadas, essa tecnologia foi sendo substituída pelo uso de semicondutores de silício, como diodos, transistores, circuitos integrados e microprocessadores, empregados nos projetos eletrônicos atuais. Mesmo com a mudança da tecnologia, muitos músicos profissionais, especialmente os guitarristas, têm preferência pelos amplificadores valvulados, fazendo com que estes atinjam valores comerciais elevados. Os estudos experimentais são sempre vistos de forma positiva no meio acadêmico, pois são complementares e estimulam a pesquisa científica. Neste trabalho foram desenvolvidas competências, desde o projeto do circuito eletrônico, quanto no uso de software para modelagem 3D e emprego da manufatura aditiva para construir o chassi do amplificador. Os objetivos deste trabalho foram estudar os princípios físicos de funcionamento das válvulas termiônicas e construir um amplificador de som estereofônico com três watts de potência por canal. Após testes, verificou-se que o funcionamento ficou dentro do esperado, resultando num produto educacional e comercial.
The Future of Agriculture
Authors: Saik Robert
Published: April 2024

“The Future of Agriculture” by Aidan Connolly offers a fast-paced and insightful exploration of how technology is transforming the agriculture and food production system. Drawing from nearly 50 articles and essays that Connolly has published in recent years, it covers a wide range of topics. The book provides a pragmatic perspective, acknowledging both the positive and negative consequences of evolving technology and serves as a resource for understanding the current state and connecting it to various players in the industry and sector.
EXCURSION AS AN EFFECTIVE MODEL FOR INTERRELIGIOUS LITERACY TO PROMOTE MODERATE CULTURE IN PLURAL SOCIETY
Authors: Subagya Agus
Published: April 2024

Moderation is more than a simple concept; it is also a way of life. In order to make moderation a daily practice, enormous efforts must be made during the process of socialization and until it becomes a movement. This study aims to describe and analyse the strategies and actions of interfaith young people in Jembrana, Bali, who promote the value of moderate culture. Using a qualitative approach through participant observation model within the framework of social construction, this study found that the excursion to the interfaith communities and religious worship houses became an effective medium for increasing moderate culture awareness and practice. The trip, as a genuine activity of young people, is the result of mapping the issues and potential actors involved in the movement by considering the network for disseminating the values of moderation. The actions initiated by the students of MAN 1 Jembrana, which then involved interfaith young people from various schools in Jembrana, started with a weekly routine discussion related to diversity issues, then continued with visits and social services to various places of worship as well as religious institutions. After all, the action ended with a declaration of fraternity and an interfaith commitment to peacekeeping
Learning from exposure to dynamics of policy and practice: Assessment of policy capacity for innovative governance that nurtures socio-political transformations
Authors: Chiome Chrispen
Published: April 2024

Southern African countries increasingly recognize that long-term growth
and productivity challenges are tightly related to the capacity to
innovate and to introduce new products, processes, services, and
organizational routines in policy practice. This research assessed
policy capacity for innovative governance as practices that aim to
satisfy socio-political transformations. It is based on original data
collected through a comprehensive survey of 30 purposively selected
senior policy managers working within the region as provincial and
national policy managers. These officials were strategically situated to
assess and reflect upon the capacity for innovative governance in their
areas of jurisdiction. The findings appear to show that Southern African
countries are affected by the government overload challenges,
bureaucracy bashing, public skepticism about the role of government;
deplorable state of support for public policy infrastructure, and
others. The research thus concludes that innovative approaches are
needed to satisfy socio-political transformations. The research
recommends rethinking the economic, social, and environmental
sustainability of current policy and practice models and implores
countries to embrace a collective reflection on finding new sources of
growth for supporting a transition towards stronger, cleaner, and fairer
economies.
A pilot randomized controlled trial of major ozone autohemotherapy for patients with post-acute sequelae of COVID-19
Authors: Hu Ke , He Yang , Liu Xu , Zha Shiqian , Wang Yixuan , Zhang Jingyi , Zhang Qingfeng
Published: April 2024

This prospective, randomized controlled trial assessed the therapeutic
effects of major ozone autohemotherapy (O -MAH) in
patients with post-acute sequelae of COVID-19 (PASC). Seventy-three
eligible participants were randomly assigned to an O
-MAH plus conventional therapy group (n=35) or an
conventional therapy alone group (n=38). Symptom score, pulmonary
function, 6-minute walk distance (6MWD), and hematological, biochemical,
and immunological parameters were evaluated before and after the
interventions. Both groups demonstrated improvements in various
parameters post-intervention, but efficacy was greater in the O
-MAH group than the conventional treatment group; with
intervention effectiveness defined as a ≥50% reduction in symptom
score, 25 of 35 patients (71%) responded to O -MAH,
while 17/38 patients (45%) responded to conventional treatment alone
(P=0.0325). Significant improvements in symptom scores (P=0.0478), tidal
volume (P=0.0374), predicted 6MWD (P=0.0032), and coagulation and
inflammatory indicators were noted in the O -MAH group
compared with the conventional treatment group. O­ -MAH
was more likely to be effective in patients with elevated CRP levels.
Furthermore, O -MAH markedly improved cellular
immunity, and this improvement became more pronounced with extended
treatment duration. In summary, combining O -MAH with
conventional treatment was more effective than conventional therapy
alone in improving symptoms, pulmonary function, inflammation,
coagulation, and cellular immunity in patients with PASC. Further
research is now warranted to validate these findings and establish the
longer-term benefits of O -MAH for PASC.
A time course analysis through diapause reveals dynamic temporal patterns of microRNAs associated with endocrine regulation in the butterfly Pieris napi
Authors: Roberts Kevin , Steward Rachel , Süess Philip , Lehmann Philipp , Wheat Christopher
Published: April 2024

Organisms inhabiting highly seasonal environments must cope with a wide
range of environmentally induced challenges. Many seasonal challenges
require extensive physiological modification to survive. In winter, to
survive extreme cold and limited resources, insects commonly enter
diapause, which is an endogenously derived dormant state associated with
minimized cellular processes and low energetic expenditure. Due to the
high degree of complexity involved in diapause, substantial cellular
regulation is required, of which our understanding primarily derives
from the transcriptome via messenger RNA expression dynamics. Here we
aim to advance our understanding of diapause by investigating microRNA
(miRNA) expression in diapausing and direct developing pupae of the
butterfly Pieris napi. We identified coordinated patterns of miRNA
expression throughout diapause in both head and abdomen tissues of
pupae, and via miRNA target identification, found several expression
patterns to be enriched for relevant diapause-related physiological
processes. We also identified two candidate miRNAs, miR-14-5p and
miR-2a-3p, that are likely involved in diapause progression through the
ecdysone synthesis pathway, a critical regulator of diapause
termination. miR-14-5p targets phantom, a gene in the ecdysone synthesis
pathway, and miR-2a-3p, which has been found to be expressed in response
to ecdysone. Together, the expression patterns of these two miRNAs match
our current understanding of the timing of hormonal regulation of
diapause in P. napi and provide interesting candidates to further
explore the mechanistic role of microRNAs in diapause regulation.
Dynamically driven correlations in elastic net models reveal sequence of events and causality in proteins
Authors: Erman Burak , Erkip Albert
Published: April 2024

Protein dynamics orchestrate allosteric regulation, but elucidating the
sequence of events and causal relationships within these intricate
processes remains challenging. We introduce the Dynamically Perturbed
Gaussian Network Model (DP-GNM), a novel approach that uncovers the
directionality of information flow within proteins. DP-GNM leverages
time-dependent correlations to achieve two goals: identifying driver and
driven residues and revealing communities of residues exhibiting
synchronized dynamics. Applied to wild type and mutated structures of
Cyclophilin A, DP-GNM unveils a hierarchical network of information
flow, where key residues initiate conformational changes that propagate
through the protein in a directed manner. This directional causality
illuminates the intricate relationship between protein dynamics and
allosteric regulation, providing valuable insights into protein function
and potential avenues for drug design. Furthermore, DP-GNM’s potential
to elucidate dynamics under periodic perturbations like the circadian
rhythm suggests its broad applicability in understanding complex
biological processes governed by environmental cycles.
Identifying marine invasion threats and management priorities through introduction pathway analysis in a remote sub-Antarctic ecosystem
Authors: Bayley Dan , Brewin Paul , James Ross , McCarthy Arlie , Brickle Paul
Published: April 2024

The threat from novel marine species introductions is a global issue.
When Non-native marine species are introduced to novel environments and
become invasive, they can affect biodiversity, industry, ecosystem
function, and both human and wildlife health. Isolated areas with
sensitive or highly specialised endemic species can be particularly
impacted. The global increase in the scope of tourism activities
together with a rapidly changing climate, now put these remote
ecosystems under threat. In this context, we analyse invasion pathways
into South Georgia & the South Sandwich Islands (SGSSI) for marine
non-native species via vessel biofouling. The SGSSI archipelago has high
biodiversity and endemism, and has historically been highly isolated
from the South American mainland. The islands sit just below the Polar
Front temperature boundary, affording some protection against
introductions. However, the region is now warming and SGSSI increasingly
acts as a gateway port for vessel traffic into the wider Antarctic,
amplifying invasion likelihood. We use remote AIS vessel-tracking data
over a two-year period to map vessel movement and behaviour around South
Georgia, and across the ‘Scotia Sea’, ‘Magellanic’, and northern
‘Continental High Antarctic’ ecoregions. We find multiple vessel types
from locations across the globe frequently now enter shallow inshore
waters and stop for prolonged periods (weeks/months) at anchor. Vessels
are active throughout the year and stop at multiple port hubs,
frequently crossing international waters and ecoregions. Management
recommendations to reduce marine invasion likelihood within SGSSI
include initiating benthic and hull monitoring at the identified
activity/dispersion hubs of King Edward Point, Bay of Isles, Gold
Harbour, St Andrews Bay and Stromness Bay. More broadly, regional
collaboration and coordination is necessary at neighbouring
international ports. Here vessels need increased pre- and post-arrival
biosecurity assessment following set protocols, and improved monitoring
of hulls for biofouling to pre-emptively mitigate this threat.
Love thy neighbour? Tropical tree growth and its response to climate anomalies is mediated by neighbourhood hierarchy and dissimilarity in carbon and water related traits.
Authors: Nemetschek Daniela , Fortunel Claire , Marcon Eric , Auer Johanna , Badouard Vincyane , Baraloto Christopher , Boisseaux Marion , Bonal Damien , Coste Sabrina , Dardevette Elia , Heuret Patrick , Hietz Peter , Levionnois Sebastien , Maréchaux Isabelle , Stahl Clément , Vleminckx Jason , Wanek Wolfgang , Ziegler Camille , Derroire Geraldine
Published: April 2024

Taxonomic diversity effects on forest productivity and response to
climate extremes range from positive to negative, suggesting a key role
for complex interactions among neighbouring trees. To elucidate how
neutral interactions, hierarchical competition and resource partitioning
between neighbours shape tree growth and climate response in a highly
diverse Amazonian forest, we combined 30 years of tree censuses with
measurements of water and carbon related traits. We modelled individual
tree growth response to climate and neighbourhood to disentangle the
relative effect of neighbourhood densities, trait hierarchies and
dissimilarities. While neighbourhood densities consistently decreased
tree growth, trait dissimilarity increased it, and both influenced
climate response. Greater water conservatism provided a competitive
advantage to focal trees in normal years, but water spender neighbours
reduced this effect in dry years. By highlighting the importance of
density and trait-mediated neighbourhood interactions, our study offers
a way towards improving predictions of forest response to climate
change.
Deeper Dive into Interoperability and Its Implications for LunaNet Communications and Navigation Services
Authors: Peura Angela , Schier James , Roura Coralí , Paulsen Phillip , Vaden Karl , Rock Jennifer , Sheehe Charles , Seibert Marc , Weir Erica
Published: April 2024

In planning for cislunar exploration and science missions, space
agencies have been collaborating to enable communications, networking,
and Position, Navigation, and Timing (PNT) systems to exchange
information and provide services to cislunar spacecraft and space
systems, thus helping each other to achieve their common goals. To
achieve commonality and lower cost for mutual benefit, the strategy of
interoperability is being adopted to help fit all the pieces together
and function smoothly. Interoperability provides cislunar users the
ability to operate in a collaborative environment similar to the
terrestrial Internet, allowing them to share information, navigate
safely despite increasing radio frequency congestion, and follow common
processes and procedures for effective joint operations. Unlike prior
government-dominated efforts, this ecosystem is expected to include
for-profit (commercial) businesses, non-profit organizations, and
academic institutions as active stakeholders. Ultimately, the goal is to
enable a cislunar ecosystem of service providers and users to contribute
to and/or utilize infrastructure and capabilities to achieve mission
objectives that span the full range of human endeavors while supporting
a variety of business models. This approach enables a Systems-of-Systems
(SoS) such as a Network-of-Networks to be sustainable in the context of
the LunaNet ecosystem as systems evolve over time in technologies,
standards, component and subsystem upgrades, and user applications. This
paper reports on the results of an effort to help frame the development
of the international LunaNet architecture by providing a canonical
definition of interoperability broad enough to meet these needs,
examining architectural and operational implications of the definition,
and exploring interoperability strategies and tactics to deploy and
evolve the services proposed for cislunar exploration and science
missions.
Inhibition of CXCR1 and CXCR2 blocks Th2/Th17-associated Allergic Lung Inflammation in Mice
Authors: Sur Sanjiv , Hosoki Koa , Govindhan Annamalai , Chakraborty Anirban , M John Knight , Hazra Tapas
Published: April 2024

Background: IL4, IL5, IL13, and IL17-producing CD4 T helper 2
(Th2)-cells and IL17-producing CD4 T helper 17 (Th17)-cells contribute
to chronic eosinophilic and neutrophilic airway inflammation in asthma
and allergic airway inflammation. Chemokines and their receptors are
upregulated in Th2-Th17-mediated inflammation. However, the ability of
CXCR1 and CXCR2 inhibition to suppress Th2 and Th17 cell-mediated
allergic lung inflammation has not been reported. Methods: Mice
sensitized and challenged with cat dander extract (CDE) mount a vigorous
Th2-Th17-mediated allergic lung inflammation. Ladarixin is an orally
bioavailable allosteric inhibitor of CXCR1 and CXCR2 and was orally
administered in this model prior to CDE-challenge. The ability of
ladarixin to modulate allergen-challenge induced recruitment of
cytokine-secreting CXCR1 and CXCR2-expressing Th2- and Th17-cells and
allergic lung inflammation were examined. Results: Allergen
challenge in sensitized mice increased mRNA expression levels of
Il4, Il5, Il13, Il6, Il1β, Tgfβ1, Il17, Il23, Gata3, and
Rorc, recruited CXCR1- and CXCR2-expressing Th2 cells,
Th17-cells, neutrophils, and eosinophils, inducing allergic lung
inflammation. Administration of ladarixin vigorously blocked each of
these pro-inflammatory effects of allergen challenge.
Conclusions: Allosteric inhibition of CXCR1 and CXCR2 by oral
administration of ladarixin vigorously blocks recruitment of CXCR1- and
CXCR2-expressing Th2-cells, Th17-cells, neutrophils, and eosinophils in
this mouse model of allergic lung inflammation. We suggest that the
ability of oral ladarixin to mitigate Th2 and Th17-mediated allergic
inflammation should be investigated in humans.
Fundamental Beliefs about emotion influence the process of emotion regulation: An ERP study
Authors: Huang Yajie , Zhang Qin , Shang Chenyang , Cui Lixia , Wei Ping
Published: April 2024

Objective: This study focused on the influences of individual beliefs
about emotion controllability (ECB) and goodness (EGB) on the process of
reappraisal and suppression using event­related potential (ERP)
approach. Method: Ninety­two participants were divided into four groups
(n = 23 for each group) according to their scores of ECB and EGB, and
then were asked to engage in a picture­based emotion regulation task
while EEG signals were recorded. Results: The results showed an
interaction among EGB, ECB and emotion regulation strategy in early
posterior negativity (EPN): Participants believing that emotions were
good and controllable displayed enhanced EPN under reappraisal compared
to suppression, implying that reappraisal instruction can potentiate
early processing of negative stimuli in these people. Furthermore, an
interaction between ECB (but not EGB) and emotion regulation was
observed in the late positive potential (LPP). The parietal LPP
(400­1000 ms) was significantly higher in negative­viewing vs.
reappraisal and suppression conditions among participants believing that
emotions were controllable, suggesting that the belief that emotions
were controllable can help individuals effectively use reappraisal and
suppression to reduce the level of unpleasant feelings. Differently,
among participants holding that emotions were uncontrollable, the
frontal (650­1700 ms) and parietal (400­1000 ms) LPPs were lower under
reappraisal vs. suppression condition, indicating that they could
benefit from the instruction of reappraisal, although they put in more
effort for suppressing facial expression. Conclusion: These results
highlight the role of emotion beliefs in emotion regulation.
Dynamic modeling of the glucose-insulin system with inhibitors impulsive control
Authors: Li Changtong , Liu Yuntao , Wang Yuzhen , Feng Xiaozhou
Published: April 2024

Pulse injection of insulin analogues is an important strategy to control
blood glucose concentrations and can be combined with α–
glucosidase inhibitors to reduce adverse effects to improve glucose
control. We propose a novel mathematical models with pulse injection
insulin and α– glucosidase inhibitors , eating in the form of
pulse blood glucose injection. The existence and uniqueness of the
positive periodic solution is confirmed In type 1 diabetes, which is
globally asymptotically stable. Further, the permanence of the system is
given in type 2 diabetes. The numerical analysis verified the
correctness of the theoretical calculation results, and show that the
period and the dose of insulin injections and α– glucosidase
inhibitors are crucial for insulin therapies. In addition, we
systematically evaluated a reasonable strategy to treat diabetes
combined with α– glucosidase inhibitors, which can provide more
reasonable clinical strategies.
Snapshot of anti-SARS-CoV-2 IgG antibodies in Covid-19 recovered patients in Guinea
Authors: GRAYO Solène , Sagno Houlou , Diassy Oumar , Zogbelemou Jean-Baptiste , Kondabo Sia Jeanne , Houndekon Marilyn , Dellagi Koussay , Vigan-Womans Inès , Rourou Samia , Hamouda Wafa Ben , Benabdessalem Chaouki , Ahmed Melika Ben , Tordo Noel
Published: April 2024

Naturally-acquired immunity following primary SARS-CoV-2 infection was
investigated from 200 patients (90% of African extraction) who
recovered from Covid-19 since at least ~ 2.4 months (72
days). The detection of IgG antibodies to SARS-CoV-2 were performed by
using an in-house ELISA assay against the Receptor Binding Domain (RBD)
of SARS-CoV-2 spike1 protein (RBD/S1-IH kit), showing 73% of positive
sera (146/200) with an Optical Density (OD) ranging from 0.13 to 1.19
and a median value of 0.56 (IC95: 0.51-0.61). Median OD value at 3
months (1.040) suddenly decreased after and remains stable around OD 0.5
until 15 months post-infection. No significant difference was found
between male (M) and female (F) (median OD values :0.62 (M) vs 0.49 (F),
P-value:0.073). In contrast, the OD median value was significantly
higher among the 60-100 age group (0.87) compared to other groups, with
a noteworthy odds ratio compared to 0-20 age group (OR: 9.69, P-value:
0.044*). Compared to a nucleoprotein ELISA commercial kit, a better
concordance was found between anti-spike1 protein ELISA (RBD/S1-IH Elisa
kit and a whole spike1 protein ELISA commercial kit) and revealed also
higher seropositivity rates. These findings emphasize the relevance of
specific ELISA kits for accurate seropositivity rates.
Assessing the impacts of sustainable land management practices using soil water hydraulic properties, penetration resistance and organic matter
Authors: Araya Prof. Tesfay , Belayneh Dr. Roza Ayalkibet , Cornelis Wim
Published: April 2024

Sustainable land management practices (SLMP) initiatives can be
evaluated using soil physical characteristics and soil organic matter
(SOM). SLMP effects on soil water hydraulic characteristics, penetration
resistance (PR), and SOM were examined at Adigudom, northern Ethiopia.
With three replications, we evaluated six land management types
(exclosure AC, crop rotation CR, conventional tillage CT, grazing land
GL, conservation agriculture CA, and fallow land FL) in Vertisols and
Leptosols soils. Soil texture, infiltration rate (IR), cumulative
infiltration (Ic), field-saturated hydraulic conductivity (Kfs), SOM,
and PR were measured. IR and Kfs were higher in AC (17.55 and 30.21 cm
hr-1, 92.8 and 83.8 cm hr-1) on Vertisols and Leptosols, respectively,
followed by CA (63.2 and 9.51 cm hr-1) on Vertisols, while the lowest IR
and Kfs were observed in GL (9.40 and 7.45 cm hr-1, 2.43 and 2.37 cm
hr-1), and CT (23.8 and 21.4 cm hr-1, 2.8 and 4.22 cm hr-1) on Vertisols
and Leptosols, respectively. In AC, CA, and FL, interventions
significantly impacted parameters derived water retention curve and PR
soil quality indicators. AC, CA, and FL improved soil quality, however,
GL and CT dryland farming reduced soil productivity. This shows how
important soil parameters are for assessing SLMP programs.
Phylogeography and paleoclimatic range dynamics explain variable outcomes to contact across a species' range
Authors: Lamb Keric , Debban Catherine , Galloway Laura
Published: April 2024

Replicability of speciation and the maintenance of divergence after
contact are poorly characterized processes, particularly in context of
phylogeography and post-glacial range dynamics. Using contact zones
located at the leading- and rear-edges of a species’ range, we examined
variation in outcomes to contact between divergent lineages of Campanula
americana. We investigated whether contact zones vary in quantity and
directionality of gene flow, how phylogeographic structure differs
between contact zones, and how historic range dynamics may affect
outcomes to contact. We found that all contact zones formed at similar
times via secondary contact yet detected significant admixture in only
the rear-edge contact zone. Across all contact zones, gene flow was
asymmetric. Our results emphasize the dependence of speciation processes
on phylogeographic structure, demographic history, and paleoclimatic
range dynamics. Our results suggest that caution need be taken when
treating species as cohesive or uniform evolutionary units.
Spatial change of dominant Baltic Sea demersal fish across two decades
Authors: MacNeil Liam , Madiraca Frane , Otto Saskia , Scotti Marco
Published: April 2024

Aim: The range and biomass distribution of marine fish species offer
insights into their underlying niches. Quantitative data are rare
compared to occurrences and remain underused in species distribution
models (SDMs) to explore patterns of realized niches– the actual space
occupied by a species shaped by abiotic and biotic factors. Local
densities drive differences in species contributions to ecological
processes and ecosystem function rather than through presence alone,
thus if a species growth rate is strongly controlled by
macro-environmental conditions, then predicting geographical abundance
or densities should be possible. Location: Baltic Sea Methods: We
collated twenty years of standardized scientific bottom trawl surveys to
fit an ensemble of SDMs to biomass (kg km) of four
dominant demersal species (Common dab, European flounder, European
plaice, Atlantic cod) within seasonal (winter and autumn) and decadal
(2001-2010; 2011-2020) time windows. Covariates were represented with
high-resolution oceanographic and habitat variables. Final prediction
maps for each species were produced by weighted ensemble averages.
Results: This work shows four distinct cases of spatiotemporal patterns.
1) Relative stasis in dab that is linked to the macro-environmental
salinity gradient in the western Baltic Sea. 2) Flounder biomass showed
spatial seasonality alongside increasing trends in the western Baltic
Sea and declines in Bornholm Basin deeps. 3) Plaice have broadly
increased in biomass density throughout the western Baltic Sea towards
present, associated with bottom salinity and temperature. 4) Both
juvenile and adult cod (≥35 cm) declined in biomass and distribution,
greatest among juvenile cod in the Gdańsk deeps and for adult cod in
Bornholm Basin by 2011-2020. Main Conclusions: This study maps biomass
of the dominant Baltic Sea demersal fish, including seasonally-explicit
patterns available from survey data. The biogeographic patterns
described here expand beyond common occurrence data and suitability
maps, which rarely discriminate between areas of high and low abundance.
Multi-objective Capacity Estimation of Wind - Solar - Energy Storage in Power Grid Planning Consideration Policy Effect
Authors: Huan Jiajia , Zhang Xiaohui , He Yu-Ling , Sun Kai , Han Zhicheng , Wang Haipeng
Published: April 2024

In order to maximize the promotion effect of renewable energy policies,
this paper proposes a capacity allocation optimization method of wind
power generation, solar power and energy storage in power grid planning
under different policy objectives. Firstly, based on the policy
quantification, grey relation analysis is used to calculate the
correlation degree of the policy indicators on the planning capacity of
renewable energy. Further, a multi-objective capacity estimation model
is comprehensively presented. Some highly correlated policy indicators
are transformed into the special constraints. And the economy and the
stability of the power grid are integrated as the objective function.
Meanwhile, the carbon trading and punishment for wind power and solar
power abandonment is considered. Finally, the proposed model is solved
by NSGA-Ⅱ-PSO algorithm. The novelty of the algorithm is that the
crossover operation of NSGA-Ⅱ is replaced by the position updating of
particle swarm. The calculation result of the case study can effectively
evaluate the optimal planning capacity of renewable energy under
different policies, while ensure the economic and the stability of the
power system. The paper can provide the reasonable basis and the valid
analytical method for the policy formulation and the renewable energy
development.
Two-stage Optimization Planning Method for Distribution Net-works with Wind-photovoltaic-storage Combined System
Authors: Qiu Shu , Deng Yujia , Ding Miao , Han Wenzhen
Published: April 2024

Existing energy capacity optimization allocation methods have
insufficient consideration of energy storage participation in scheduling
and the model’s complexity with low calculation accuracy. Hence, this
paper es-tablishes a two-stage optimization model of wind, solar, and
energy storage in the joint planning of energy storage and distributed
power supply. Firstly, an objective function is employed to minimize
losses and volt-age deviation in the distribution network system. Then,
an improved multi-objective particle swarm algo-rithm is used to
determine the optimal location and capacity of distributed generation
access to the distribu-tion network, introducing a conceptual indicator
for voltage magnitude safety to identify alternative nodes and reduce
model calculations. Subsequently, energy storage is allocated at the
optimal location, and an op-timal dispatch model is established with the
economic objective of minimizing the integrated operating cost of wind
and solar storage. Finally, the rationality of the model and algorithm
is verified using the IEEE33 distribution system as an example. The
approach effectively improves the economy of distribution network
operation, enhances the voltage quality, and reduces network losses.
Effect of oncology nurse navigation on mental health in patients with cancer in Taiwan: a randomized controlled clinical trial
Authors: Chang Hsiu-Ju , Yu Wei-Zhen , Wang Hsin-Fang , Lin Yen-Kuang , Liu Yen-Lin , Yen Yun , Whang-Peng Jacqueline , Huang, Tsai Wei
Published: April 2024

Background Evidence shows that nurse navigation is effective
for patients diagnosed with cancer. Research on the effects of oncology
nurse navigation on mental health is ongoing, but few studies have
investigated the impact of such interventions on medical experience,
demoralization, and distress. Further, nurse navigation is rarely
implemented in Taiwan. Aims To investigate the prevalence of
mental health problems and whether oncology nurse navigation improved
the mental health outcomes and medical experience of patients with
cancer. Methods and results In this randomized controlled
clinical trial, we recruited 128 outpatients with cancer via purposive
sampling from a teaching hospital in northern Taiwan. Participants were
randomly assigned to the navigation group (received navigator and usual
care; N = 61) or the usual-care group (received usual care only;
N = 67). Questionnaires included the self-reported Distress
Thermometer, Hospital Anxiety and Depression Scale, Demoralization
Scale, and Patient Assessment of Chronic Illness Care. Data were
collected at baseline and after three and six months of the intervention
and analyzed using descriptive statistics and unpaired t,
Mann–Whitney U, chi-squared, and Fisher’s exact tests.
Generalized estimating equations were used to analyze differences
between the groups. The prevalence rates of anxiety, depression,
distress, and demoralization were 17.9%, 15.7%, 29.7%, and 29.7%,
respectively. After three months, participants in the navigation group
exhibited significantly reduced anxiety (odds ratio [OR] = 0.106,
p = 0.003), demoralization (OR = 0.294, p = 0.017), and
emotional distress (OR = 0.314, p = 0.047), and reported a better
medical experience (OR = 1.418, p = 0.020) than those in the
usual-care group. However, there was no significant treatment effect at
six months. Conclusions Oncology nurse navigation may offer
benefits for the mental health and medical experience of patients with
cancer. Nurse-navigator roles and programs should thus be expanded
across healthcare systems.
First-line Treatment Patterns and Outcomes in Advanced Non-Small Cell Lung Cancer in Sweden: A Population-based Real-world Study with Focus on Immunotherapy
Authors: Wagenius Gunnar , Vikström Anders , Berglund Anders , Salomonsson Stina , Bencina Goran , Hu Xiaohan , Chirovsky Dana , Brunnström Hans
Published: April 2024

Background and purpose: The treatment landscape for patients with advanced non-small cell lung cancer (NSCLC) has evolved significantly since the introduction of immunotherapies. We here describe PD-L1 testing rates, treatment patterns, and real-world outcomes for PD-(L)1 inhibitors in Sweden.
Materials and methods: Data were obtained from the Swedish National Lung Cancer Registry for patients with advanced NSCLC and Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0–2 who initiated first-line ­systemic treatment from 01 April 2017 to 30 June 2020. PD-L1 testing was available in the registry from 01 January 2018. Kaplan-Meier was used for overall survival (OS) by type treatment and histology.
Results: A total of 2,204 patients with pathologically confirmed unresectable stage IIIB/C or IV NSCLC initiated first-line treatment, 1,807 (82%) with nonsquamous (NSQ) and 397 (18%) with SQ. Eighty-six per cent (NSQ) or 85% (SQ) had been tested for PD-L1 expression, a proportion that increased over time. The use of platinum-based therapy as first-line treatment decreased substantially over time while there was an upward trend for PD-(L)1-based therapy. Among patients with PS 0–1 initiating a first-line PD-(L)1 inhibitor monotherapy, the median OS was 18.6 and 13.3 months for NSQ and SQ NSCLC patients, respectively, while for the PD-(L)1 inhibitor and chemotherapy combination regimen, the median OS was 24.0 months for NSQ and not evaluable for SQ patients.
Interpretation: The majority of advanced NSCLCs in Sweden were tested for PD-L1 expression. Real-world OS in patients with PS 0–1 receiving first-line PD-(L)1 inhibitor-based regimens was similar to what has been reported in pivotal clinical trials on PD-(L)1 inhibitors.
The Impact of Technology Readiness on Undergraduate Students’ Acceptance of Learning Management System
Authors: Maryani Ika , Puspitasari Yunita Mega
Published: April 2024

The problem raised in this research is that there are no studies that measure the influence of technology readiness on student acceptance of the Learning Management System. This research aims to analyze the influence of technology readiness on acceptance of the Learning Management System among students. This research uses a quantitative approach with an ex post facto type. The research method uses associative research to determine the causal relationship between technological readiness and the Learning Management System. The data collection technique uses a technology readiness questionnaire and the Learning Management System which is then analyzed using simple linear regression analysis with t-test hypothesis testing. The questionnaire consists of 27 valid statements representing indicators, optimism, innovation, discomfort, insecurity, usefulness, ease of use, and interest in using. Questionnaires were distributed to students via WhatsApp using accidental sampling technique and obtained 152 respondents. The results show that 66.8% of acceptance of the Learning Management System is influenced by technology readiness. Meanwhile, 33.2% is influenced by other variables. The results of this research indicate that there is a positive influence of technology readiness on acceptance of the Learning Management System. This means that the higher the technological readiness, the higher the acceptance of the Learning Management System. The implication is that technological readiness must be improved to optimize the use of the Learning Management System. High acceptance of the Learning Management System can provide support for the success of the online learning process.
Digital Technologies: A Congregating pan-African Public Management on the Fourth Industrial Revolution for Employability and Sustainable Growth
Authors: Atianashie Miracle , Adaobi Chukwuma Chinaza , Adinkrah-Appiah Kwadwo , Obeng-Ofori Daniel
Published: April 2024

The Fourth Industrial Revolution (4IR) is the concept of blurring the real world with the technological world and it is characterized by a range of new technologies that are fusing the physical, digital, and biological worlds. The study analyze the state of pan-African public administration practice within the praxis of the Fourth Industrial Revolution (4IR) to enhance employability and sustainable development. The 4IR is the concept of blurring the real world with the technological world, and a range of new technologies that are fusing the physical, digital, and biological worlds characterizes it. At its core, the 4IR is driven by the convergence of physical and digital technologies. It is the current developing environment in which disruptive technologies and trends such as the Internet of Things (IoT), robotics or intelligent robots, mobile supercomputing, virtual reality (VR), and artificial intelligence (AI) are changing the way people live and work. Furthermore, the study interrogates the contentious and contemporary potentials of the pan-African public administration vis-à-vis the fourth industrial revolution as we draw closer to the future. The study employed a descriptive research design, relying on content analysis. A secondary source of data collection was employed. Some of the significant findings include sustainable development, Employability, and Fourth Industrial Revolution. The study advocates that for African public administration to be relevant to the governance and sustainable development needs of the continent, it must restructure its educational curriculum to take advantage of the benefits that the technological advancement of the fourth industrial revolution provides.
Bilingual E-Magazine: The Development of Digital Teaching Resource on Students’ Literacy of Environmental Pollution
Authors: Vonti Lungguh Halira , Indriyani  , Ganeswara M. Ginanjar , Rahmah Mursidah , Rosyid Abdul
Published: April 2024

Based on research in ASIA, Indonesia is still in the lowest position in the term of literacy. Moreover, the students’ interest of using and exploring conventional teaching materials is also still low. One of the materials given in every level of education now is PLH or Environment Education. The government concerns about environment education should be supported by the availability of appropriate and interactive teaching media. Therefore, this study aims to develop and produce digital teaching media for the subject under the topic of environment pollution as well as improving students’ literacy and understanding of the subject material in PLH subject. The research employed research and development design started with analysis process, designing process, development process, implementation and evaluation process. The result of the research is E-Magazine as one of the Learning resources that contain learning materials that are displayed attractively with more interesting features such as images, videos, and interesting display. The result of the product’s implementation shows that the students’ digital literacy of environmental pollution is increased by the score of 82,11%. Based on results analysis of the students’ understanding of the environmental pollution for the subject, the N-gain score was 0,83 and it was higher than 0,70 as the standard for high level effectiveness.
E-Sistus: Electronic Information System for Students with Special Needs in Supporting Inclusive School Management
Authors: Antari Agung Dewi Megah , Agung Anak Agung Gede , Sulindawati Ni Luh Gede Erni
Published: April 2024

Providing data for students with special needs is still manual, to make it easier to access the data, a digital information system needs to be developed so that its functions can be implemented more quickly. In line with these needs, this research aims to develop an e-information system for students with special needs to support inclusive school management. This research develops E-Systus development in accordance with the ADDIE development model. This research uses 4 (four) techniques in data collection, namely observation, interviews, questionnaires, and tests. This research uses qualitative descriptive analysis techniques, quantitative descriptive analysis and inferential statistical analysis. The results of this research found that the product feasibility level based on content experts obtained a percentage of 90% in the very good category. The product feasibility level based on instructional design experts obtained a percentage of 91.6% in the very good category. The level of product suitability based on media experts obtained an average value of 97.5% in the very good category. The product feasibility level based on individual trials obtained a percentage result of 94.16% which is in very good qualifications. The product feasibility level based on small group trials obtained a percentage result of 93.33% which is in very good qualifications. The Electronic Information System for Students with Special Needs (E-Sistus) has been proven to be significantly effective in supporting inclusive school management.
Live Worksheets Media to Improve Exploration of Dance Movements of Grade II Elementary School Students
Authors: Husnawati Riska Nidaul , Nurharini Atip
Published: April 2024

One important aspect of dance education is the exploration of dance movement, which not only builds motor skills but also provides a platform for developing students' identity and emotional expression. This research aims to develop E-LKPD based on Live worksheets to increase students' exploration of dance movements. The subjects of this research were material experts, media experts, class II teachers, and 25 class II students. This type of research is Research and Development (RnD) using the ADDIE model. The data collection methods for this research are observation, interviews, questionnaires, documentation, and tests. The data analysis technique is qualitative and quantitative descriptive analysis. Quantitative data can be in the form of an increase in the average learning outcomes of dance movement exploration which can be calculated using the N-Gain Test. The research results were that the validation test by teaching materials experts was 95% with very feasible criteria, and the validation test by media experts received a score of 97% with very feasible criteria. The N-gain test results show a value of 0.7, meaning it has high criteria. Live worksheets-based E-LKPD teaching materials are feasible and effective for increasing movement exploration for second-grade elementary school students. E-LKPD teaching materials are flexible and efficient to use.