bluuebunny/crossref_metadata_2025 huggingface dataset:
Vulnerability to disaster in the Maldives: The Maamigili and Fenfushi island communities
Authors: Borg Axisa Glorianne , Borg Ruben Paul , Ibrahim Mohamed Haikal , Nistharan Fathimath
Published: November 2022

The relation between vulnerability and environmental threats in islands depends on the geographical conditions of specific islands rather than general assumptions. It is assumed that different island communities may develop different socio-environmental dynamics depending on the ordinary everyday context, which would determine their resilience to real and perceived risks. This research provides data on communities’ perception of their vulnerability to environmental issues, with the objective of understanding the sense of vulnerability of two neighbouring island communities in the Maldives: Maamigili and Fenfushi. The research is based on qualitative and quantitative methods which include semi-structured interviews with national and local entities, and questionnaires distributed among island inhabitants. The study shows that although the islands are located in very similar geographical settings, the socio-environment dynamics within each of the islands determines the communities’ sense of vulnerability. The communities of Maamigili and Fenfushi face different situations and, as such, general assumptions would not address the gaps and needs of communities of specific islands. Even if two islands are relatively close and similar to each other, they still require separate Disaster Risk Reduction strategies so as to address the real and perceived short- and long-term vulnerabilities of the locals as a means to build more resilient communities.
ENGLISH EDUCATION STUDENTS’ PERCEPTION OF INSTAGRAM USAGE AS A MEDIUM TO LEARN ENGLISH
Authors: Anindita Kezia , Noveintine Dhanesvar Karel
Published: November 2022

The popularity of Instagram made people increasingly use it well, one of which is to learn new languages. English as an international language is a language that is being encouraged to be mastered by people. The objective of this study is to know how EFL students use Instagram as an English learning medium. The data collected was from ELESP students’ batch 19-21 who learn English with Instagram as the learning medium. This study was conducted in a descriptive qualitative method by distributing an open-ended questionnaire. This study result showed that ELESP students have a positive perception of Instagram usage as the learning medium to learn English. ELESP students deliver how Instagram can enhance vocabulary, grammar, and pronunciation knowledge, and also gain new information.
To question of manufacturing zinc reference electrodes for sea-going vessels and ships
Authors: Yastrebov Dmitry Pavlovich
Published: November 2022

The article highlights the urgent problem of corrosion protection monitoring of sea-going vessels and ships. Nowadays, the ship teams provide the control by measuring the potential of the ship hull using reference electrodes. There are given the results of monitoring the corrosion protection of the hull of the sea-going vessel PM-15 project No. 304/III. The control system is based on the results of measuring the potential of the ship hull. The measurements were taken using a standard silver chloride reference electrode (SCE) and two nonstandard electrodes made of galvanized steel. In manufacturing the non-standard reference electrodes there were taken into account the requests of the crews of sea-going vessels of the Kamchatka fleet. Testing the reference electrodes of galvanized steel proves that the results of measuring the potential of the ship hull can be classified as accurate measurements in accordance with GOST R 8.736-2011. The measuring results are quite stable according to GOST R 8.736-2011. It has been stated that the cost of CSE is several times higher than the cost of reference electrodes made of galvanized steel. The process of storing and transporting CSE is more labour-intensive compared to the galvanized steel reference electrodes. The galvanized steel reference electrodes provided for protecting the marine hulls from corrosion are recommended for use. It has been inferred that manufacture and application of non-standard reference electrodes on ships can be provided by ship repair crews. The study results can be used by the crews of sea-going vessels to control the protection

of ship hulls against corrosion.
ANALISA DAN PERANCANGAN SISTEM INFORMASI PERPUSTAKAAN
Authors: Nugraha Fajar
Published: November 2022

ABSTRAK Dunia pendidikan tidak lepas dari keberadaan koleksi bahan pustaka yang dimiliki. Semakin meningkatnya atau bertambahnya koleksi bahan pustaka, kebutuhan informasi yang berkaitan dengan bahan pustaka yang ada, keterbatasan petugas pelayanan perpustakaan merupakan beberapa permasalahan yang seringkali timbul dalam pengelolaan perpustakaan. Tujuan penelitian ini adalah membuat sistem informasi untuk menangani proses tersebut agar dapat meningkatkan pelayanan kepada para pengguna perpustakaan. Dengan rancangan sistem informasi perpustakaan ini, diharapkan dapat memberikan pelayanan yang maksimal kepada pengguna perpustakaan dan meminimalkan kesalahan dalam pengolahan data. Sistem informasi perpustakaan dimulai dari pendataan anggota, pendataan buku, peminjaman buku, pengembalian buku, pemberian surat bebas perpustakaan dan pembuatan laporan meliputi laporan data anggota, laporan data buku, laporan peminjaman buku, laporan pengembalian buku serta laporan penerimaan denda. Manfaat sistem informasi perpustakaan ini diharapkan dapat meningkatkan pelayanan kepada pengguna perpustakaan dan memperlancar proses administrasi menjadi lebih cepat dan akurat. Kata kunci: sistem informasi, pelayanan, perpustakaan.
La teoría del actor-red desde América Latina. Libro editado por Leandro Rodriguez-Medina, María de los Ángeles Pozas y Lidia Girola
Authors: Galindo Jorge
Published: November 2022

El presente texto reseña el libro La teoría del actor-red desde América Latina editado por María de los Ángeles Pozas, Lidia Girola y Leandro Rodriguez-Medina. Es una muestra de los rendimientos que esta teoría ha tenido en América Latina. Los comentarios a los catorce capítulos que componen la obra se dividen en cuatro secciones: textos en los que se aclara el significado o se ejemplifica el uso de alguno de los conceptos centrales de la Teoría del Actor-Red (TAR), textos que sirven como guías metodológicas para aprender a hacer investigación con ésta, textos en los que se vincula a tal teoría con otras perspectivas y textos críticos sobre la TAR.
Toward an Inclusive Theology: Muhammad Syahrur's Hermeneutical Interpretation of Religious Inclusivism based on Al-Quran
Authors: Barsihannor  , M. Ilham  , Gustia Tahir  , Hamdanah
Published: November 2022

Many experts have authored studies on Islamic theology to understand religion in the modern world. The research on religious inclusivism is essential for the literature since many researchers continuously contribute to it. This work analyzes Muhammad Syahrur's Hermeneutical interpretation of religious inclusivism based on the Al-Quran. This research is library research using a qualitative-descriptive approach to explore the views, ideas, concepts, and theories given by Muhammad Syahrur linked to inclusive theology. This research claims that religious inclusivism is highly necessary to create and expand as human interaction is becoming intensive in the current digital era. In this regard, Syahrur proposes a solution to establish religious inclusivism by referring to the content of the verses of the Quran as a moral foundation and life advice that contains verses that are always under the situations of the times and locations. This study offers theoretical implications to improve the literature based on religious inclusivism.
El gran reinicio del conocimiento y su impacto en las Humanidades Digitales
Authors: Fiormonte Domenico
Published: November 2022

En este artículo se describe el impacto de GAFAM (Google, Apple, Facebook, Amazon y Microsoft) sobre la educación pública y en general se analiza el cambio de paradigma en la producción y acceso al conocimiento digital. La pandemia de COVID-19 favoreció la expansión de los oligopolios globales y la plataformización de procesos y servicios: información, educación, salud, transportes, alimentación, etc. Al generar efectos de estandarización y homogeneización, estos fenómenos constituyen una amenaza para la diversidad biocultural y paralizan la innovación tecnológica. En este escenario es necesario que las Humanidades Digitales recuperen su papel crítico y reconviertan la originaria pulsión hermenéutica y epistemológica en conciencia política. El objetivo de las HD hoy debería ser defender y fortalecer la variación y la pluralidad cultural, lingüística y epistémica en la dimensión digital.
SOSIALISASI PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE NHT DENGAN PENDEKATAN REALISTIK MTS MADANI ALAUDDIN
Authors: Dahlia Dahlia , Nur Fitriani , Andi Mattoliang Lisnasari , Tayeb Thamrin , Rasyid Muhammad Rusydi , Sulasteri Sri
Published: November 2022

Pengabdian ini diarahkan untuk mensosialisasikan penerapan model Kooperatif Tipe Numbered Head Together (NHT) dengan Pendekatan Realistic Mathematics Education (RME) di MTs. Madani Alauddin Pao-pao. Kegiatan ini diikuti oleh seorang guru dan 27 orang siswa kelas VIII MTs. Madani Alauddin Pao-pao. Instrumen yang digunakan dalam penelitian ini adalah tes hasil belajar siswa dan dianalisis menggunakan statistik deskriptif yakni rata-rata, kategorisasi hasil belajar matematika, standar deviasi dan koefisien varians relatif. Capaian dari kegiatan ini membuktikan bahwa penerapan model pembelajaran kooperatif tipe NHT dengan pendekatan RME cukup efektif dalam meningkatkan hasil belajar matematika pada siswa kelas VIII MTs. Madani Alauddin.
PENDAMPINGAN PRAKTIKUM IPA BIOLOGI PESERTA DIDIK MAN 2 BARRU
Authors: Ali Ahmad , Rapi Muh , Arif Wiwin Pramita , Rivai Andi Tenri Ola , Zulkarnaim Zulkarnaim , Ibrahim Ayyub
Published: November 2022

Kegiatan praktikum merupakan kegiatan wajib pada pembelajaran sains khususnya biologi. Praktikum menjadikan pengalaman peserta didik untuk menunjukkan keterampilan proses dalam menemukan teori atau fakta maupun sebatas pembuktian teori yang telah ada. Sayangnya Kegiatan praktikum belum dilaksanakan secara optimal di MAN 2 Barru mengingat keterbatasan alat dan bahan yang ada. Pengabdian ini dilaksanakan di Madrasah Aliyah Negeri 2 Barru dengan subjek pendampingan adalah peserta didik kelas X, XI, XII yang berjumlah 20 orang. Praktikum yang dilaksanakan berjumalah 6 topik dengan menggunakan bahan dan alat sederhana yang dapat dijumpai di sekitar sekolah atau lingkungan sekitar. Praktikum menunjukkan antusias peserta didik dalam mengikuti praktikum. Peserta didik telah mampu menggunakan mikroskop, membuat preparate, dan mengamati di bawah mikroskop, membedah katak dan menunjukkan  bagian morfologi dan anatominya, membuat hipotesis dan menarik kesimpulan pada setiap topik praktikum.
PROGRAM PENDAMPINGAN DAN PEMBERDAYAAN KELOMPOK MASYARAKAT PADA KOMUNITAS TULI PEDULI BITUNG (KALEB)
Authors: Pranata Putra Onky , Karim Qadri , Alam Syamsul , Ilda Nildawati , Basri Syahrul , Amansyah Munawir , Ibrahim Hasbi , Habibi
Published: November 2022

Kegiatan pendampingan dan pemberdayaan kelompok masyarakat pada komunitas tuli peduli bitung (KALEB) bertujuan untuk mengembangan potensi penyandang disabilitas (tuli) untuk mendapatkan kesempatan aktualisasi diri dan meningkatkan kepercayaan diri. Kegiatan ini dimulai dengan pemberian bantuan alat dengar, dilanjutkan dengan pemberian buku belajar Bahasa isyarat. Selanjutnya dilakukan pendampingan pengolahan sampah anorganik pada semua anggota KALEB, pengolahan limbah organik sebagai objek kerajinan komunitas teman–teman tuli. Kegiatan lainnya adalah pembentukan kafé literasi, percetakan sablon serta edukasi Bahasa isyarat. Hasil kegiatan pendampingan dan pemberdayaan kelompok masyarakat pada komunitas tuli peduli bitung (KALEB) memunculkan secercah asa kepada seluruh peserta KALEB bahwa mereka juga adalah bagian dari masyarakat. Peserta KALEB bangkit dari keterbelakang mental dan rasa tidak percaya diri. Dukungan alat bantu dengar, pengadaan buku belajar bahasa isyarat, program edukasi bahasa isyarat, hingga program-program sosial ekonomi, semakin meyakinkan teman-teman tuli sesungguhnya mereka pun dapat hadir di tengah-tengah masyarakat umum.
The Gummy Smile and its Concern among Dental Students - A Survey
Authors:   Assistant Professor, Department of Oral and Maxillofacial Surgery, Chettinad Dental College and Research Institute, Kelambakkam, Tamil Nadu, India, Yolanda Jessica
Published: November 2022

Context: A smile can be displeasing when there is eexcessive gingival show. Currently, correction of a gummy smile is becoming a prime demand by the patients. An exposure of 3 mm of gingival tissue is diagnosed as a gummy smile. Many reasons contribute to a gummy smile and the availability of treatment options falls under a wide range. Aims: The aim was to assess knowledge among dental students on the gummy smile and its treatment plans. Methods and Material: The questions were given as Google forms to the participants of the study. Students pursuing bachelors in dentistry were chosen for the study. A set of 20 questions were framed in a questionnaire form with multiple choice questions and students were asked to pick out a single option from provided questions. Questions asked were on the etiology of the gummy smile, lip repositioning procedures, use of botox and gum contouring procedures. Results: The results depict a correlation between the different treatment modalities of the gummy smile but the choice of treatment is governed by various factors such as patient’s expectation, expenditure, and aesthetic sense and the skill set of the clinician. This study reveals good knowledge among the participants regarding the factors related to a gummy smile. Conclusion: In a nutshell, this study indicates that the dental undergraduates have a good knowledge about the gummy smile and its treatment options available. They have an insight about the available treatment modalities but are not equipped with adequate knowledge regarding the diagnostic criteria.
Draw A Person Test: A Case Study
Authors:   Research Scholar, Maharaj Vinayak Global University, Jaipur, India, Ranga Nipun
Published: November 2022

The case study examined the significance of draw a person test to measure the child’s emotional issues. These days children suffer from variety of problems and are vulnerable to abuse and traumas. They are prone to substance abuse to illegal activities. They have difficulty expressing their thoughts and feelings due to many different reasons. Drawing can be used to know the child’s inner struggle and can be used to gain more insight about children’s emotional state. The present case study is used to analysed 5th standard school student who had behavioural problems using Draw-a-Person test.
Effects of Different Types of Meditation on Diastolic Blood Pressure
Authors:   Director of Physical Education, Government Arts and Science College, Vanur, Villupuram, India, Panbilnathan Aranga
Published: November 2022

Background: The study was intended to find out the effects of different types of meditations namely transcendental meditation and heart rhythm meditation on diastolic blood pressure among male college students. Methodology: Sixty male students studying bachelor’s degree in colleges in and around Tiruvannamalai District, Tamil Nadu, India were randomly selected as subjects to achieve the purpose of this study. The age of subjects ranged between 18 and 24 years, height and weight ranged from 158 to 171 cm and 56 to 69 kg respectively. The selected sixty subjects were divided into three groups of twenty subjects each at random. Group I (transcendental meditation), Group II (heart rhythm meditation) and Group III (control). Prior to and immediately after the training programme, all the subjects of three groups were tested on the selected dependent variable. ANCOVA (analysis of covariance) was used to analyse the collected data to find out the effects of different types of meditations on diastolic blood pressure. Whenever the obtained ‘F’ ratio for the adjusted post-test mean was found to be significant, Scheffe’s test was applied as post hoc test to determine the paired mean differences, if any. The 0.05 level of confidence was fixed to test the level of significance which was considered as an appropriate. Results & Conclusion: There was a significant differences exist among transcendental meditation group, heart rhythm meditation group and control group on selected physiological variable namely diastolic blood pressure. There was significant change on selected physiological variable namely diastolic blood pressure due to transcendental meditation and heart rhythm meditation after twelve weeks of training period. Significant differences were found between transcendental meditation group and heart rhythm meditation group on selected physiological variable namely diastolic blood pressure after twelve weeks of training period.
O USO DE VITAMINA D NO CONTEXTO DA PANDEMIA DA COVID-19
Authors: Da Silva do Nascimento Giovanna , Fachinelli Fernanda , De Meneses Eli Cristiano
Published: November 2022

O SARS-CoV-2, coronavírus responsável pela Síndrome Respiratória Aguda Grave 2 (COVID-19) identificado em dezembro de 2019 em Wuhan, na China, ocasionou a contaminação em massa de chineses, que posteriormente atingiu todo o mundo. Por se tratar de um vírus recém-descoberto, não há até o momento em que este artigo foi escrito um tratamento eficaz para a doença. Devido a sua alta taxa de contaminação, muitas pessoas procuram medicamentos e suplementações, como a vitamina D, a fim de evitar a contaminação pelo vírus, porém não há evidências concretas de que esses produtos previnem a infecção. Deste modo, baseando-se na revisão bibliográfica e na coleta e análise de dados de moradores da Região Metropolitana de Campinas, o objetivo deste estudo foi evidenciar o aumento do uso da vitamina D e sua relação com a pandemia do novo coronavírus, os riscos do seu uso indiscriminado e o papel do profissional da saúde diante deste cenário. Foi possível constatar um aumento da suplementação de vitamina D no período da pandemia de COVID-19 impulsionado pelo aumento de indicações realizadas por profissionais da saúde nas mídias sociais e por meio de prescrições médicas. Recomenda-se cautela na prescrição da suplementação de colecalciferol para indivíduos sem antes realizar um exame, a fim de constatar os níveis séricos de vitamina D no organismo, deste modo determinando a necessidade ou não da suplementação. A suplementação inadequada pode gerar efeitos colaterais e distúrbios metabólicos que podem debilitar o paciente.
Correction to: Hepatic hydatid cyst – diagnose and treatment algorithm
Authors: Botezatu Cristian ,   “Colentina” Clinical Hospital, General Surgery Clinic, Bucharest,   “Carol Davila” Medical University, Bucharest, Mastalier Bogdan ,   “Colentina” Clinical Hospital, General Surgery Clinic, Bucharest,   “Carol Davila” Medical University, Bucharest,   Mastalier B, “Carol Davila” Medical University, “Colentina” Hospital. E-mail: bogdanmastalier@yahoo.com, Patrascu Traian ,   “Carol Davila” Medical University, Bucharest,   “Dr. I. Cantacuzino” Clinical Hospital, General Surgery Clinic, Bucharest
Published: November 2022

In the original publication, the corresponding author field has been omitted. The correct corresponding author name is: Bogdan Mastalier. The original article is now corrected.
Correction to: An investigation into the prevalence of cognitive impairment and the performance of older adults in Guilan province
Authors: Soleimani Robabeh ,   Psychiatry Department, Kavosh Cognitive Behaviour Sciences and Addiction Research Center, Shafa educational – remedial Hospital, Associate Professor, Guilan University of Medical Sciences, Rasht, Iran, Shokrgozar Somayeh ,   Psychiatry Department, Kavosh Cognitive Behaviour Sciences and Addiction Research Center, Shafa educational – remedial Hospital, Assistant Professor, Guilan University of Medical Sciences, Rasht, Iran,   Somayeh Shokrgozar, Psychiatry Department, Kavosh Cognitive Behaviour Sciences and Addiction Research Center, Shafa educational – remedial Hospital, Assistant Professor, Guilan University of Medical Sciences, Rasht, Iran. Dr.shokrgozar@yahoo.com. Phone: +989113313008, Fallahi Mahnaz ,   Vice-chancellor for health, Guilan University of Medical Sciences, Rasht, Iran, Kafi Hashem ,   Guilan University of Medical Sciences, Rasht, Iran, Kiani Maryam ,   Guilan University of Medical Sciences, Rasht, Iran
Published: November 2022

In the original publication, the corresponding author name has been incorrectly typeset as: Robabeh Soleimani. The correct corresponding author name is: Somayeh Shokrgozar. The original article is now corrected.
Correction to: A Doctor Discovers Michelangelo’s Self-Portrait in San Bartholomew’s Flayed Skin in the Sistine Chapel
Authors: Licata Marta ,   Centre of Research of Osteoarchaeology and Paleopathology, Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy,   Dr. Marta Licata, Centre of Research of Osteoarchaeology and Paleopathology, Department of Biotechnology and Life Sciences, University of Insubria, O. Rossi, 9, 21100 Varese, Italy. marta.licata@uninsubria.it
Published: November 2022

In the original publication, the author name and the corresponding author field have been omitted. The author name is: Marta Licata. The original article is now corrected.
Green tea improves rat sperm quality and reduced cadmium chloride damage effect in spermatogenesis cycle
Authors: Mahmoudi Reza ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Azizi Arsalan ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Abedini Soheila ,   Biology Department, Azad University of Jahrom, Jahrom, Iran, Hemayatkhah Jahromi Vahid ,   Biology Department, Azad University of Jahrom, Jahrom, Iran, Abidi Hassan ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Jafari Barmak Mehrzad ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran,   Mehrzad Jafari Barmak, Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran; Tel.: +98–743 3230290; E-mail: mehrzadj14@gmail.com.
Published: November 2022

Introduction

Testicular tissue is part of the reproductive system that some mineral compounds such as cadmium chloride (CdCl2) destroy. Green tea (Camellia sinensis) extract can reduce the tissue damage caused by toxins due to its antioxidant properties. The aim of this study was to evaluate the effect of green tea extract on sperm quality in cadmium chloride toxicity.

Materials and Methods

In the present study, male Wistar rats were allotted randomly into four groups, namely control group (C), CdCl2 (1.5mg/kg), GT 1.5% (w/v) and in combinationCdCl2+GT groups. CdCl2 was injected intraperitoneally (1.5 mg /kg) whereas the green tea extract was administrated orally. At 13, 25 and 49 days after treatment, the rats were euthanized and the reproductive organs (testes, epididymis) were excised and used for sperm analysis and histo-morphometric examinations.

Results

The mean of the diameter of seminiferous tubes, the number of spermatogonia, Sertoli, Leydig cells and thickness of the germinal layer in the testis were significantly increased (P<0.05) in all groups compared to the CdCl2 group (P<0.05). Sperm motility, sperm count and testosterone were significantly decreased in the CdCl2 group compared to all groups of treatment (p<0.05). The mean of MDA was significantly increased in the CdCl2 group compared to other groups (p<0.05).

Conclusion

Green tea has an antioxidant effect that reduces the effects of free oxygen radicals produced from toxins such as cadmium chloride. In addition, it could decrease lipid peroxidation of the cell membrane and ultimately prevent the destruction of tissues in the long run.
Cost-Effectiveness Analysis of Treatment for Metastatic Renal Carcinoma in Romania
Authors: Liviu Preda Alin ,   Public Health and Management Department, Carol Davila University of Medicine and Pharmacy, Bucharest,   Alin Liviu Preda, Catedra de Sanatate Publica si Management, Institutul de Sanatate Publica, Str. Dr. Leonte Anastasievici Nr.1-3, Sector 5, cod: 050463, Bucharest, Romania, Galieta Mincă Dana ,   Public Health and Management Department, Carol Davila University of Medicine and Pharmacy, Bucharest
Published: November 2022

Rationale

In recent years, the cost of several treatment options for renal cancer have been supported by the Romanian healthcare system for both first- and second-line therapies. First-line alternatives through real-life efficacy and amplitude of adverse reactions may influence the efficacy and costs of patients treated with second-line treatment.

Objective

Estimation of the cost-effectiveness and cost-benefit ratio for first-line treatment alternatives: Sunitinib and Pazopanib from the payer’s perspective in the Romanian healthcare system.

Methods and Results

We developed a Markov model to calculate the cost-effectiveness and cost-benefit ratio for 2 cohorts of patients using the results from the COMPARZ study for efficacy (progression-free survival, general survivability and quality of life) and safety and costs from national hospital databases. For an estimated population of 800 patients, Pazopanib has a quantified benefit of 7.19 years in progression-free survival, 11.71 life years gained and 8.97 years of quality-adjusted life-years compared to Sunitinib. The analysis is limited by the accuracy of the national data used and the transposition of general data on efficacy and safety at the local level.
The Attitude of Patients from a Romanian Tertiary Cardiology Center as Regards Participation in Biomarker-Based Clinical Trials – Survey Methodology
Authors: Mihaela Micheu Miruna ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   Miruna Mihaela Micheu, Department of Cardiology, Clinical Emergency Hospital of Bucharest, Floreasca street 8, 014461, Bucharest, Romania, Phone: +40722451755, E-mail: mirunamicheu@yahoo.com., Udrea Oana-Maria ,   Department of Psychology, “Grigore Alexandrescu” Clinical Hospital of Bucharest, Bucharest, Romania, Octavia Popa Mihaela ,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Rusu Iulia ,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Gheorghe-Fronea Oana ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Scafa-Udriste Alexandru ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Dorobantu Maria ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Published: November 2022

One of the challenges faced when conducting a clinical trial is the recruitment of the proposed number of participants. Accordingly, identifying barriers to patients’ enrollment and developing effective strategies to overcome them is mandatory. One of the main strategies employed to improve participation rate consists of designing the informed consent forms based on patients’ feedback. This survey aims to explore the attitude of patients admitted in a Romanian tertiary cardiology center to take part in biomarker-based clinical trials.

This is a descriptive, prospective and longitudinal single-center study. Participants will be recruited until the planned sample size will be reached (n=333). The patients will be interviewed based on a semi-structured questionnaire which includes four sections: demographics (7 items), personal medical history (7 items), attitudes (9 items) and trust (4 items). Descriptive statistics will be used to illustrate patients’ demographics, medical history, attitudes toward biomarker-based clinical trials and trust in medical researchers. Logistic regression models will be employed to assess relations between patients’ attitudes, trust, and different socio-demographic variables.

Data analysis will offer answers to key questions addressed by this survey: What amount of and in what form should information be disclosed? Who should make the invitation to participate?

The information gained will facilitate tailoring informed consent forms to suit the needs of patients with various demographic, social and educational backgrounds.
Time trend analysis of breast cancer in Iran and its six topographical regions: a population-based study
Authors: Bab Sattar ,   Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran, Abdifard Edris ,   Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran,   Iran Nursing and Midwifery School, Iran University of Medical Sciences, Tehran, Iran, Elyasianfar Shahin ,   Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran, Mohammadi Payam ,   Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran, Heidari Mohammad ,   Clinical Research Development Unit of Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran,   Mohammad Heidari, Clinical Research Development Unit of Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran, E-mail: Heidari.m@umsu.ac.ir
Published: November 2022

Breast cancer is the most common cancer among women, and in 2002 it was expected that 636,000 new cases would occur in developed countries and 514,000 in developing countries. Although the incidence rate of this cancer in Asian countries is lower than in Western countries, whereas the incidence trend increasing rapidly in Asia. Using the data from the Cancer Registry System, this study was carried out to investigate the incidence trend during 2000–2005 in Iran and its six geographical areas. The incidence rates were standardized according to age-sex groups by Excel directly and confidence intervals is calculated for the point estimations by Stata11. The trends were analyzed separately based on gender, age groups for different provinces by Poisson regression in Stata11. The age standardized incidence rate in 2000 was 0.1 and 3.4 per 100,000 in males and females, respectively, reaching 0.5 and 16.7 per 100,000 in 2005. The incidence trends in all geographical areas of the country were increased despite the difference in the slopes. The sex ratio of male to female was 31.6 and the mean age of the patients was 49.4 (±12.6) years. The incidence of breast cancer in Iran was lower than the European and Asian countries but the trend is in rising. Although this increase is due to the increase in the prevalence of risk factors among Iranian population. Improvement in the coverage of the cancer registry system as well as the screening programs are important factors for these changes.
Cox-2 inhibitors in mandibular third molar surgery
Authors: Janarthanan K. ,   Reader, Department of OMFS, RMDC & H, Annamalai University, India,   Dr. K. Janarthanan, Annamalai University Faculty of Dentistry, Department of OMFS, Chidambaram, Annamalai Nagar, India, E-mail: mrisidda@gmail.com, Adalarasan S. ,   Lecturer, Department of OMFS, RMDC & H, Annamalai University, India
Published: November 2022

Pain control during and after any surgical procedure, is extremely essential for the comfort of patients. Pain killers used routinely act by inhibiting cyclooxygenase to control pain and inflammation. Cox-1 is constitutively expressed in most cell types, including platelets, whereas Cox-2 is absent from most healthy tissues but is induced by pro-inflammatory or proliferative stimuli. Cox-1 plays a role in the production of prostaglandins involved in protection of the gastric mucosal layer and thromboxanes (TX) in platelets. Cox-2 generally mediates elevations of prostaglandins associated with inflammation, pain, and pyresis. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen are generally nonselective inhibitors of Coxs. This lack of selectivity has been linked to their propensity to cause gastrointestinal side effects. The new Cox-2 selective inhibitors, or coxibs, show the same anti-inflammatory, analgesic, and antipyretic effects as nonselective NSAIDs but are supposed to have reduced side-effect profiles. This study evaluates whether rofecoxib (50 mg) given one hour pre-operatively or the same drug given one hour post-operatively is more effective in controlling the pain and swelling in mandibular third molar surgery.
Evaluation of quality of life and self-efficacy in adolescents with amblyopia
Authors: Mazlominezhad Akram ,   1. Department of Nursing and Midwifery, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran, Moghadam Farhad Adhami ,   2. Department of Ophthalmology, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran,   Farhad Adhami Moghadam, Department of Ophthalmology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. E-mail: farhad.adhami@gmail.com
Published: November 2022

Amblyopia is an acquired defect due to a lack of visual stimulation. Self-efficacy is one of the factors affecting the quality of life (QoL) of individuals. Low self-efficacy can decrease cognitive and behavioral functioning, whereas increased self-efficacy leads to a change in treatment acceptance behavior and, subsequently, physical and mental health. This study aimed to determine the QoL and self-efficacy in adolescents with amblyopia. This descriptive cross-sectional study was performed on 300 patients referred to hospitals affiliated with Mashhad University of Medical Sciences, Iran, between 2015 and 2016. Data collection tools included: 1) demographic questionnaire, 2) general self-efficacy scale, and 3) WHO QoL questionnaire. Data were analyzed using SPSS software 24 using descriptive statistics. The results showed that the mean percentage in QoL was 45.43% (weak), and the mean score in self-efficacy was 21.66%, with a standard deviation of 8.10. There was also a positive and significant relationship between patients' self-efficacy and QoL on each dimension. This study showed that demographic characteristics had no significant relationship with any of the variables of QoL and self-efficacy. However, data analysis showed a significant and positive relationship between self-efficacy and QoL.
One-year follow-up of patients with hyperopia undergoing photorefractive keratectomy with Allegretto WaveLight Eye Q 400
Authors: Shahin Behrad ,   1. Department of Community Medicine, Ardabil University of Medical Sciences, Ardabil, Iran, Ojaghi Habib ,   2. Department of Surgery, Ardabil University of Medical Sciences, Ardabil, Iran,   Habib Ojaghi, Department of Surgery, Ardabil University of Medical Sciences, Ardabil, Iran. E-mail: dr.habibojaghi@gmail.com,   https://orcid.org/0000-0002-8372-2185, Amani Firouz ,   1. Department of Community Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
Published: November 2022

This study aimed to examine the effectiveness of photorefractive keratectomy (PRK) in treating patients with cycloplegic hyperopia from +1.00 to +7.00 diopter using Allegretto wave Eye Q 400. This study was conducted on 25 patients with cycloplegic astigmatism ≤1 diopter and cycloplegic hyperopia between +1.00 and +7.00 diopters in 47 eyes, who successively entered into the study within 6 months and underwent PRK. Prior to PRK surgery, all the patients were examined for cycloplegic refraction (astigmatism and hyperopia), slit lamp, keratometry, fundus, and best-corrected (BCVA) and uncorrected visual acuity (UCVA) testing. These examinations were repeated after 1 week, 1 month, 3 months, 6 months, and 1 year postoperatively. The mean preop UCVA of patients was 0.76±0.28 (ranging from 0.00 to 1.3), which reached 0.19±0.22 (ranging from 0.00 to 0.78) one year after the surgery (P=0.000). There was a significant correlation between increasing astigmatism and preop cycloplegic hyperopia >5 diopters (P=0.000), corneal ring haziness at 12th months (P=0.000), and 12 months cycloplegic residual hyperopia ≥2.00 diopters (P=0.000). 53.2% of the eyes (with a mean grade of 2.34) were detected with corneal ring haziness at 12th months, which was significantly correlated with 12 months residual cycloplegic hyperopia of ≥2.00 diopters (P: 0.000) and cycloplegic sphere above 5 diopters (P=0.006). Although the use of photorefractive keratectomy (PRK) with Allegretto Eye Q 400 is associated with a decrease in the mean cycloplegic and improved UCVA and BCVA, its use is not recommended in cases with preop cycloplegic hyperopia above 5 diopters due to the high rate of induction of astigmatism, corneal haziness, and regression of hyperopia.
The role of epithelial membrane antigen (EMA) overexpression in the prognosis of prostatic adenocarcinoma
Authors: Ghalib Rawaa ,   1. Department of Pathology, College of Medicine, Babylon University, Babylon, Iraq,   Rawaa Ghalib, Department of Pathology, College of Medicine, Babylon University, Babylon, Iraq. E-mail: dr.rawaaghali123@gmail.com., Falah Athraa ,   1. Department of Pathology, College of Medicine, Babylon University, Babylon, Iraq,   Athraa Falah, Department of Pathology, College of Medicine, Babylon University, Babylon, Iraq. E-mail: athraafalahhassan@gmail.com
Published: November 2022

Prostatic adenocarcinoma is the second-most common cancer in men and the fifth most common cause of cancer death. Its incidence increases with age; 75% of patients are 65 years and older. The aim of the study was to assess epithelial membrane antigen (EMA) expression in prostatic adenocarcinoma as a poor prognostic marker and its correlation to some pathological parameters. The formalin-fixed, paraffin-surrounded tissue blocks were retrospectively collected from 40 men diagnosed with prostate carcinoma. All cases were collected from Al Hilla Teaching Hospital and some private labs between October 2018 – November 2020, with ages ranging from 30–89 years. Statistical analysis was done using SPSS 22, frequency and percentage were used for categorical data, and Chi-square was used to evaluate connotation between variables. P-value ≤0.05 was significant. The blocks were sectioned for EMA immunohistochemical staining using monoclonal mouse anti-human EMA protein. EMA protein overexpression was detected in 75% (n=30/40) of prostatic adenocarcinoma cases. EMA expression showed no correlation with the patient's age (P=0.09) and a positive correlation with the cancer grade (P=0.003). In prostatic adenocarcinoma patients, EMA could be seen as a potential prognostic predictor for disease progression.
A novel approach in diagnosing multiple dentigerous cysts using CBCT illustration indicative of Mucopolysaccharidosis VI – a case report
Authors: Rai Shalu ,   1. Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Kadrabad, India,   Shalu Rai, Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Kadrabad, India. E-mail: drshalurai@gmail.com, Misra Deepankar ,   1. Department of Oral Medicine and Radiology, Institute of Dental Studies and Technologies, Kadrabad, India, Misra Akansha ,   2. Department of Oral Pathology, Institute of Dental Studies and Technologies, Kadrabad, India, Jain Ankit ,   3. Department of Oral Medicine and Radiology, DJ Dental College and Research Centre, Modinagar, India, Verma Ashish ,   4. Department of Periodontology, Sudha Rastogi College of Dental Sciences and Research, Faridabad, India, Grover Dimple ,   5. Department of Oral and Maxillofacial Surgery, Sudha Rastogi College of Dental Sciences and Research, Faridabad, India, Haris Ayesha ,   6. Project Officer, Institute of Liver and Biliary Sciences, Delhi, India
Published: November 2022

Mucopolysaccharidosis VI is a genetic disorder affecting multiple organs with sundry clinical presentations. The main etiological factor reflects the disturbances in mucopolysaccharide metabolism leading to deposition of acid mucopolysaccharide in various tissues. The pathognomonic features of the disease include a large head, short neck, corneal opacity, open mouth associated with an enlarged tongue, enlargement of the skull, and long anteroposterior dimension with unerupted dentition, dentigerous cyst-like follicles, condylar defects, and gingival hyperplasia. An 18-year-old boy with Maroteaux-Lamy syndrome (mucopolysaccharidosis type VI) is described in this article, emphasizing the oral manifestations and radiographic illustration of lesions in the jaws. It also emphasizes the essential role of cone-beam computed tomography to identify and analyze multicentric pathologies in the jaws.
The efficient use of smartphone apps to improve the level of asthma knowledge
Authors: Ghozali Muhammad Thesa ,   1. School of Pharmacy, Universitas Muhammadiyah Yogyakarta, Yogyakarta, Indonesia,   https://orcid.org/0000-0002-7665-0603, Satibi Satibi ,   2. Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia,   Satibi Satibi, Department of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia. E-mail: satibi@ugm.ac.id,   https://orcid.org/0000-0002-5894-9425, Ikawati Zullies ,   3. Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia,   https://orcid.org/0000-0002-4812-055X, Lazuardi Lutfan ,   4. Department of Health Policy and Management, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia,   https://orcid.org/0000-0001-5146-8162
Published: November 2022

Patient education is one of the important aspects of improving knowledge and quality of asthma control. In this digital era, it can be made with the support of an app – or known as mHealth. Unfortunately, implementing applications for patient education is relatively new among asthmatic patients in Indonesia. This study aimed to determine the efficacy of the educational content of the AsmaDroid® app on the levels of asthma knowledge among asthmatic patients. This study was a randomized controlled trial carried out from December 2019 to March 2020 in the Special Region of Yogyakarta, Indonesia. A quota sampling was employed, resulting in 140 study participants being categorized into control and treatment groups. Before and after the 4-week treatment period, all participants were asked to complete a pre-test and post-test of the Asthma General Knowledge Questionnaire for Adults (AGKQA) questionnaire. All the scores were then compared to determine the efficacy of educational content on the levels of asthma knowledge. The results of descriptive statistics reported that the pretest scores of AGKQA from the control group (minimum, maximum, and mean) were 9, 25, and 19.04±2.56, respectively, and post-test scores were 10, 27, and 18.79±3.59 (p=0.47). Meanwhile, in the treatment group, these were 13, 25, and 19.11±2.87, while post-test scores were 16, 31, 23.6±3.95 (p=0.01). Additionally, there was a difference between the post-test scores of the control and treatment groups, namely 4.81 (p=0.01). The educational content of the app significantly improved the levels of asthma knowledge.
Cytokine production in Ancylostoma duodenale infection
Authors: Shlash Shaimaa Abdulhussein ,   1. Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq, Alzubaidi Zubaida Falih ,   1. Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq,   Zubaida Falih Alzubaidi, Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq. E-mail: zubaidahf.mezaal@uokufa.edu.iq, Saleh Huda Ali ,   1. Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq
Published: November 2022

Cytokine response to Ancylostoma duodenale (A. duodenale) infection was measured after starting treatments with piperazine. This study aims to determine the impact of cytokine production after infection with A. duodenale before and after treatment with piperazine. Blood and stool samples of 50 patients with A. duodenale infection and 28 healthy individuals (control) were collected. In this study, IFNγ, IL-5, IL-12, and IL-13 in serum (using ELISA-based methods) were measured. Stool samples were examined using the Kato-Katz technique to detect A. duodenale parasites. Blood and stool samples were analyzed 14 days after starting piperazine treatment for A. duodenale infection. The medium concentration of IFNγ, IL-5, IL-12, and IL-13 in the serum samples with A. duodenale infection is higher than that of the control group. IFNγ, IL-5, IL-12, and IL-13 levels were significantly higher in the infected individuals (10.5±7.4 pg/ml, 14.6±5.1 pg/ml, 8.5±3.2 pg/ml and 13.6±7.5 pg/ml respectively) than the control group (4.7±2.4 pg/ml, 7.8±4.06 pg/ml, 6.3±3.4 pg/ml and 3.5±2.7 pg/ml respectively). Also, piperazine treatment can significantly reduce cytokines levels (IFN-γ: P=0.043, IL-5: P=0.02, and IL-12, p=0.001). This study shows that piperazine treatment can reduce cytokines profiles in patients with A. duodenale infection.
Fibular hemimelia
Authors: Georgescu Tiberiu ,   1. National Institute of Mother and Child Care Alessandrescu-Rusescu, Bucharest, Romania,   2. Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Ionescu Olivia ,   3. Department of Obstetrics and Gynecology, South Nurnberg Hospital, Nurnberg, Germany, Toader Oana Daniela ,   1. National Institute of Mother and Child Care Alessandrescu-Rusescu, Bucharest, Romania,   2. Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Bacalbasa Nicolae ,   2. Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Pop Lucian Gheorgea ,   1. National Institute of Mother and Child Care Alessandrescu-Rusescu, Bucharest, Romania,   Lucian Gheorghe Pop, National Institute of Mother and Child Care Alessandrescu-Rusescu, Bucharest, Romania. E-mail: popluciangh@icloud.com
Published: November 2022

Fibular hemimelia is defined as a partial or complete absence of the fibula. Alongside fibular deformities, there is a wide spectrum of anomalies, foot deformities, and absent rays. A literature review showed only a handful of cases of prenatal diagnosis of fibular hemimelia. It is a rare disorder that might be isolated or associated with visceral anomalies.
رسوم الاحتفال بتولية الخليفة العباسي والسلطان المملوكي في دولة المماليك البحرية(648-784هـ/1250-1383م):
Authors: Al Jandeel Hashim Saab , Salih Al Jubory Mukhlaf Abdullah
Published: November 2022

تعد دراسة رسوم الاحتفال بتولية الخليفة العباسي والسلطان المملوكي من المواضيع الجديرة باهتمام الباحثين فبعد سقوط الخلافة العباسية في بغداد على يد المغول ، اعتقد كثير من الناس ان الخلافة العباسية قد انتهت بمقتل اخر الخلفاء في بغداد ، ولكن بعد احياء الخلافة العباسية في القاهرة على يد السلطان الظاهر بيبرس تجدد الامل عند الناس بعودة الخلافة، فبعد وصول اول خليفة عباسي الى القاهرة والتأكد من نسبه، أقيمت لها احتفالات ورسوم خاصة ، أصبح الخليفة يمثل الجانب الروحي في البلاد وهو الذي يمنح السلطان الجديد التفويض بالحكم وسط احتفالاً كبيراً وهذه الرسوم قسم منها مقتبسة من الفاطميين والايوبيين والقسم الاخر من اختراع المماليك ، فكان على السلطان أن يلبس الخلعة التي يمنحها له الخليفة ويتقلد السيف والطوق في عنقه للدلالة على إنه من المماليك، ويسير في القاهرة وسط احتفال شعبي كبير، ويركب فرساً خاص به، والامراء في خدمته وتحمل فوق رأسه المظلة ، ثم يصعد الى قلعة الجبل مقر حكم السلطان لتكتمل رسوم الاحتفال بتقبيل الارض بين يدي السلطان ويحلفون على المصحف الشريف ثم يمد سماطاً عظيماً.