bluuebunny/crossref_metadata_2025 huggingface dataset:
Colorectal Cancer Prevalence and Survival in Castilla La Mancha (Spain). A Pilot Study
Authors: González Laura Valiente , Ibáñez Ricardo de Miguel , Sotos Francisco Escribano
Published: September 2021

Background: Colorectal cancer is the most commonly diagnosed cancer type and the second cause of cancer death in Spain. The primary risk factor for colorectal cancer is age, with 90% of all diagnosed patients aged over 50 years. Prognosis mainly depends on tumour stage. Aim: Conduct a pilot Colorectal Cancer prevalence and survival study in Cuenca (Spain) since there are almost no studies based on small populations. This is the first pilot study about survival in screening of colorectal cancer carried out in hospitals in Castilla La Mancha. Methods and Results: Retrospective descriptive cohort study was performed to include patients with colorectal cancer diagnosed by colonoscopy between May 2015 and April 2016, and who were followed up for 48 months. The study considered sociodemographic and clinical data of the patients. Survival curves were estimated using the Kaplan-Meier method. The proportional hazard rate associated with age, gender, stage and presence of metastasis was calculated using the Cox regression method. 57 patients were included in the study. The mean follow-up was 45.5 months. Ten patients died during the study, in seven cases the cause was colorectal cancer. The percentage of patients alive at 48-month follow-up were 82.4%. Conclusion: Colon cancer is a high-prevalence pathology, with adenocarcinoma being the most common histology. The results seem to indicate that it affects men more frequently, mortality rises with tumour stage at diagnosis and declines with use of chemotherapy. We present a pilot study that could justify large-scale epidemiological studies for the regional surveillance and evolution of colorectal cancer in Spain.
Association Between Levels of Urine Di-(2-ethylhexyl)phthalate Exposure, a Potentially Harmful and Invisible Chemical, and Heart Rate Variability in Young Adults
Authors: Chen Ching-Way , Hwang Jin-Shiang , Hsu Cheng-Chih , Lin Chien-Yu , Su Ta-Chen
Published: September 2021

BackgroundPhthalate exposure is associated with cardiovascular risk. Among the various phthalates, di-(2-ethylhexyl) phthalate (DEHP) is the most important plasticizer in our daily lives. This study investigated the association between DEHP exposure and the alteration of heart rate variability (HRV).MethodsDuring 2017-2019, we recruited 974 young adults to investigate the effects of living environments and dietary habits on cardiometabolic disorders in Taiwan. We quantitatively analyzed urinary metabolites of phthalates, including mono-(2-ethylhexyl) phthalate (MEHP), mono-(ethyl-5-hydroxyhexyl) phthalate (MEHHP), and mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP). A continuous electrocardiogram was recorded to obtain a 5-minute ECG. Time-domain and frequency-domain HRV analyses were performed.ResultsMultiple linear regression showed that urinary oxidized DEHP metabolites MEHHP and MEOHP were associated with decreased HRV after controlling for associated cardiovascular risk factors. A higher MEHHP level was associated with a lower TINN (triangular interpolation of NN interval histogram), very-low-frequency (VLF), and low frequency/high frequency (LF/HF) ratio. A higher MEOHP level was associated with a decreased LF/HF ratio. In addition, trend analysis showed that higher MEHHP and MEOHP quantiles were significantly associated with a decreased LF/HF ratio.Conclusions﻿DEHP is a potentially harmful and invisible chemicals. The urinary DEHP metabolites MEHHP and MEOHP are associated with decreased HRV, indicating an unfavorable autonomic balance in young adults in Taiwan.
Plasma fibrinogen as a predictor of residual renal function in patients undergoing peritoneal dialysis
Authors: Qi Ling , Huang Peipei , Wang Xiaoping , Zhu Shan , Wang Xiaomei , Su Zhen
Published: September 2021

Background： Inflammatory markers are powerful predictors of prognosis in patients undergoing peritoneal dialysis (PD). Plasma fibrinogen (FIB), an inflammatory marker, is considered an independent predictor of cardiovascular events and mortality in PD patients. However, little is known about the association between FIB and residual renal function (RRF) in PD patients. Material/Methods: We reviewed the clinical data of patients who started PD between January 2012 and December 2020 at the First Affiliated Hospital of Wenzhou Medical University. This study covered 472 patients in total. Residual renal function (RRF) was determined by a 24-hour urine collection and calculated from the average of creatinine and urea clearance. Clinical and biochemical data at the initiation of peritoneal dialysis was collected as baseline data. Results: The median follow-up duration was 31.55 (20.43-49.00) months. The RRF reduction rate was significantly greater in patients in the high-fibrinogen group (fibrinogen >4.0 g/L) compared with those in the control group (fibrinogen ≤4.0 g/L; 0.13 ± 0.15 mL/min/month/1.73m2 vs. 0.088 ± 0.10 mL/min/month/1.73m2; p<0.001). Using multiple linear regression analysis and adjusting for other risk factors, high FIB was an independent predictor of rapid RRF decline (P=0.033). The Cox proportional hazard model and the competing risk model revealed that an elevated plasma FIB level (HR=1.219, 95%CI 1.058-1.404; SHR=1.154, 95%CI 1.012-1.317) was independent factors for the progression to anuria. Conclusions: We demonstrated that a higher plasma fibrinogen level was significantly associated with a higher rate of RRF decline, and hyperfibrinogenemia was an independent risk factor for anuria in PD patients.
Neuroprotective Effects of Alisol A 24-acetate on Cerebral Ischemia-reperfusion Injury by Regulating PI3K/AKT Pathway
Authors: Lu Taotao , Li Huihong , Zhou Yangjie , Wei Wei , Ding Linlin , Zhan Zengtu , Liu Weilin , Tao Jing , Xue Xiehua
Published: September 2021

BackgroundNeuroinflammation and apoptosis are involved in the pathogenesis of ischemic stroke. Alisol A 24-acetate (24A) has a strong inhibitory effect on inflammation and cell apoptosis. The neuroprotective effect of 24A in the global cerebral ischemia/ reperfusion (GCI/R) is still unclear. Methods GCI/R mice was used to investigated the neuroprotective effect of 24A. Modified neurological deficit scores, Morris Water Maze and object recognition test were used to evaluate behaviors. The metabolism in brain regions was detected by MRS. The changes of microglia, astrocytes and neurons was detected. The inflammation and apoptosis were measured.Results The results showed that 24A improved behavioral dysfunction and brain metabolism, alleviate neuroinflammation and apoptosis, inhibited microglia and astrocytes activation, which is associated with the activation of PI3K/AKT pathway. ConclusionsTaken together, our study demonstrated that 24A could alleviate GCI/R injury through anti-neuroinflammation and anti-apoptosis via regulating the PI3K/AKT pathway.
Risk of Hepatitis B Virus Reactivation in HBsAg-negative, Anti-HBc-negative Patients Receiving Rituximab for Autoimmune Diseases in Hepatitis B Virus Endemic Areas
Authors: Lan Ting-Yuan , Lin Yen-Chun , Tseng Tai-Chung , Yang Hung-Chih , Kao Jui-Hung , Cheng Chiao-Feng , Lee Tai-Ju , Huang Shang-Chin , Lu Cheng-Hsun , Li Ko-Jen , Hsieh Song-Chou
Published: September 2021

Background

Rituximab is known to be associated with a high resolved hepatitis B virus (HBV) reactivation rate in patients with resolved HBV infection and hematologic malignancy. However, data regarding HBV reactivation in rheumatic patients receiving rituximab is limited.
Aims

To assess the HBV reactivation in HBsAg-negative patients receiving rituximab for autoimmune diseases in a large real-world cohort.
Methods

From March 2006 to December 2019, 900 patients with negative HBsAg receiving at least one cycle of rituximab for autoimmune diseases in a tertiary medical center in Taiwan were retrospectively reviewed. Clinical outcomes and factors associated with HBV reactivation were analyzed.
Results

After a median follow-up period of 3.3 years, 21 patients developed HBV reactivation, among which 17 patients were positive for anti-HBc and 4 were negative. Thirteen patients had clinical hepatitis flare, while 8 patients had HBsAg seroreversion without hepatitis. Old age, anti-HBc positivity, and undetectable serum anti-HBs level at rituximab initiation were associated with HBV reactivation. There was no significant difference in the HBV reactivation risk between rheumatoid arthritis and other autoimmune diseases. Among anti-HBc-negative patients, subjects without HBV vaccination at birth had an increased risk of HBV reactivation (4/368, 1.1%) compared with those who received vaccination (0/126, 0%).
Conclusions

In HBV endemic areas, patients with negative anti-HBc, especially those without vaccination at birth, were still at risk for HBV reactivation after receiving rituximab. Regular monitoring of HBV serology should be considered for all HBsAg-negative patients receiving rituximab for autoimmune diseases.
Bodies moving with sound: Effects of pitch and musical sounds on body-representations
Authors: Ley-Flores Judith , Alshami Eslam , Singh Aneesha , Bevilacqua Frédéric , Bianchi-Berthouze Nadia , Deroy Ophelia , Tajadura-Jiménez Ana
Published: September 2021

The effects of music on bodily movement and feelings, such as when people are dancing or engaged in physical activity, are well-documented - people may move in response to the sound cues, feel powerful, less tired. How sounds and bodily movements relate to create such effects? Here we deconstruct the problem and investigate how different auditory features affect people’s body-representation and feelings even when paired with the same movement. In three experiments, participants executed a simple arm raise synchronised with changing pitch in simple tones (Experiment 1), rich musical sounds (Experiment 2) and different absolute frequency ranges (Experiment 3), while we recorded indirect and direct measures on their movement, body-representations and feelings. Changes in pitch influenced people’s general emotional state as well as the various bodily dimensions investigated – movement, proprioceptive awareness and feelings about one’s body and movement. Adding harmonic content amplified the differences between ascending and descending sounds, while shifting the absolute frequency range had a general effect on movement amplitude, bodily feelings and emotional state. These results provide new insights in the role of auditory and musical features in dance and exercise, and have implications for the design of sound-based applications supporting movement expression, physical activity, or rehabilitation.
Exploring risky practices, Opioid Substitute Therapy (OST) and disease transmission among prison inmates in India - A cross-sectional study
Authors: Adhikary Anoshmita , Hossain Shaikh Shah , Narayanan Prakash
Published: September 2021

Background: Prison, a setting where high-risk persons including substance-use offenders are being convicted. They sometimes continue their risky behaviours which pose a risk to themselves, other prisoners and to the community. A cross-sectional study was conducted in ten correctional homes (CHs) in West Bengal to identify the substance use, sexual and hygiene practices among prison inmates inside correctional homes. Methods: In-depth interviews were conducted with 15 key informants posted inside prisons using an interview guide. Data were analysed using MS Excel 2019. Chi-Square tests were performed to ascertain the associations between variables.Results: This study confirmed the availability and use of substances within prisons, and homosexual as well as drug-injecting practices of inmates. According to key informants, many CH inmates have had infections such as contact dermatitis, scabies, UTIs, STIs, tuberculosis, HIV, and hepatitis B and C. Limited preventive and curative services such as healthy diet, isolation and treatment for HIV and TB were provided to infected inmates. The treatment completion rate in inmates who availed OST at CHs was 96.53%, while the re-addiction rate after released from prison was 98.07%. The routine screening for STIs and hepatitis, distribution of condom and needles, and treatment for hepatitis were absent in most CHs. The CHs lack mechanisms to ensure continuous drug supply, regular follow-up and treatment completion after incarceration, partner notification, hepatitis treatment, and health promotions.Conclusions: The improvements in infrastructure and uninterrupted health care delivery system can improve health outcomes of affected inmates and break the transmission to other inmates and general community.
Multiplex Immunohistochemistry Applies to Examination of PD-1/PD-L1 on Immune Cells for Prognosis Prediction in Non-Small Cell Lung Cancer
Authors: Chen Huiyong , Liao Hongliang , Gong Longlong , Liu Jingting , Zhou Lin , Kang Lin , Zheng Hongbo , Wan Renping
Published: September 2021

Background: Tumor cells expressing programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) correlate with a better prognosis of immunotherapy in non-small cell lung cancer (NSCLC) patients. Expression of PD-1 and PD-L1 on immune cells is also concerned by more and more researchers.Methods: This study included 174 patients with NSCLC, and collected from the month of December in 2012 to April 2019. Formalin-fixed paraffin-embedded (FFPE) samples from NSCLC patients were performed by multiplex immunohistochemistry (IHC) staining using CD8, CD57, CD68, CD163, PD-1 and PD-L1. Marker localization included each type of immune cell subset with PD-1 or PD-L1 was quantified and analyzed.Results: The present study revealed distribution characteristics of PD-1 and PD-L1 on CD8+ T cells, CD57+ NK cells, CD68+ macrophages and CD163+ M2 macrophages in NSCLC patients using multiplex IHC, which indicated that expression of PD-1 was higher on CD8+ T cells and expression of PD-L1 was higher on CD8+ T cells and CD68+ macrophages. Immune clustering analysis showed that the low immune feature group displayed more survival rate than the high group. The reason was due to higher ratios of CD8/PD-L1 in the low group compared with the high group in the NSCLC cohort. Further, the Kaplan-Meier analysis of survival rate according infiltration of different immune cells also indicated that low CD57+ NK cells and low CD68+ macrophages were associated with a higher survival rate. The similar results were observed in the Kaplan-Meier analysis of expression of PD-1 and PD-L1 on immune cells.Conclusions: Taken together, we displayed the expression characteristics of PD-1 and PD-L1 on tumor-infiltrating immune cells and revealed that high expression of PD-1 and PD-L1 on immune cells was associated with poor survival rate. The present study provided further evidence to better guide clinical treatment in NSCLC.
Source Tracking of Chicken Infectious Anemia Virus in a SPF Chicken Population, the Latest Report in China
Authors: Li Yan , Wang Jinjin , Zhang Yawen , Wang Yixin , Zhao Hui , Miao Xinyuan , Chi Zengna , Wang Qun , Cui Zhizhong , Chang Shuang , Zhao Peng
Published: September 2021

BackgroundLive attenuated vaccines have been extensively used to prevent infectious disease in poultry flocks. However, exogenous virus contamination in attenuated vaccines had been reported several times in the past, which brought enormous threat to poultry production and diseases prevention and control. Recently, an attenuated vaccine against Newcastle Disease produced in China was detected contamination with chicken infectious anemia virus (CIAV) in a routine inspection for exogenous virus. To understand the multiple routes of transmission of CIAV, and to better formulate correct prevention and control, it is necessary to find out the possible source of this contamination.Methodslood samples of SPF chickens that generated vaccines were collected to investigate CIAV antibody titers by ELISA test. Then, 14- to 18-day-old SPF chicken embryos (n=40) were randomly selected, DNA was extracted and detected by quantitative real-time PCR and nucleic acid dot hybridization assays. To further investigate the molecular features of the CIAV isolate, the complete genome of CIAV was amplified and analyzed.ResultsThe results showed both SPF chickens and embryos for vaccine preparation were CIAV-positive. In addition, the full-length genome sequences of CIAV from vaccines and SPF chicken embryos were consisted of 2,298 nucleotides (nt) with 100% homology, named as SDSPF2020 (Genbank accession number: MW660821). It demonstrated 95.7%-99.6% homology with the complete nucleotide sequences of reference strains, and shared the closest evolution relationship with the Chinese strain HLJ15125. Conclusion﻿This study illustrated that vertical transmission of CIAV from SPF chickens and embryos was an important way for exogenous virus contamination in vaccine production. As such, vaccine quality monitoring and health control are significant in the poultry industry from an environmental safety point of view.
Succession in the Caecal Microbiota of Developing Broilers Colonised by Extended-spectrum β-lactamase-producing Escherichia Coli
Authors: Cardenas-Rey Ingrid , Gonzalez Teresita Bello , Goot Jeanet Van der , Ceccarelli Daniela , Bouwhuis Gerwin , Schillemans Danielle , Jurburg Stephanie , Veldman Kees , De Visser Arjan , Brouwer Michael
Published: September 2021

BackgroundBroilers are among the most common and dense poultry production systems, where antimicrobials have been used extensively to promote animal health and performance. The continuous usage of antimicrobials has selected for resistant bacteria, such as e Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-Ec) . Here, we studied the ESBL-Ec prevalence and successional dynamics of the caecal microbiome of developing broilers in a commercial flock during their production life. Broilers were discriminated as ESBL-Ec colonised or not by selective culturing. Using 16S rRNA gene sequencing, we compared the richness, evenness and composition of the cecal microbiota of both broiler groups and assessed the combined role of age and ESBL status on the microbiota. ResultsWe observed a linear trend in the proportions of ESBL-Ec throughout the broilers' production round, X 2 (1, N = 12) = 28.4, p < .001. Over time, microbial richness was consistently higher in ESBL-Ec free broilers, but significant differences between both groups were found exclusively on day three (Wilcoxon rank-sum test, p = .016). Bray-Curtis distance-based RDA (BC- dbRDA) showed no explanatory power of ESBL status, while age explained 14% of the compositional variation of the caecal microbiome, F (2, 66) = 6.47, p = .001. ConclusionsThis study assessed the role of ESBL-producing E.coli in the successional dynamics of the cecal microbiome in developing broilers and shows that the presence of ESBL-producing E.coli is associated with mild but consistent reductions in alpha diversity and transient compositional differences. We also reported the clonal spread of ESBL and point to the farm environment as a likely source for ESBLs.
Negative Effects of Acute Appendicitis in Children During COVID-19 Pandemic: Analysis of 1,274 Cases.
Authors: Delgado-Miguel Carlos , Urbán Julia Garcia , Ferrer Celia Del Monte , Muñoz-Serrano Antonio , Sarmiento María del Carmen , Moratilla Lucas , Miguel-Ferrero Miriam , De Ceano-Vivas María , Martínez Leopoldo
Published: September 2021

Introduction: Since the COVID-19 pandemic confinement was established in Spain on March 9, 2020, the number of visits to the paediatric Emergency Department (ED) has decreased dramatically, probably due to the fear of parents becoming infected in the hospital environment. The aim of this work is to analyse the medium-term consequences during the first 9 months after the onset of the COVID-19 pandemic in children with acute appendicitis (AA).Methods: A retrospective study was performed on children operated on for AA in our institution between 2017-2020, who were distributed in two groups according to the date of surgery: COVID-19 group (after March 9, 2020) and control group (before March 9, 2020). Demographic variables, associated symptoms, time from symptoms onset, hospital stay, rate of complicated AA and postoperative complications were analysed.Results: A total of 1274 patients were included (288 COVID group; 986 control group), without demographic differences between them. Time from symptom onset was significantly longer in COVID-19 group patients (34.5 vs. 24.2 hours; p=0.021), although no differences in associated symptoms were observed between both groups. COVID-19 group patients presented a higher rate of complicated AA (20.1% vs. 14%; OR: 1.55; CI95%[1.10-2.18]; p=0.008), a longer hospital stay (3.5 vs. 2.8 days; p=0.042) as well as a higher rate of postoperative complications (21.5% vs. 15.7%; OR: 1.47; CI95%[(1.06-2.04)]; p=0.008).Conclusion: This study shows the negative medium-term effects of the COVID-19 pandemic on children with acute appendicitis: delayed ED visits, increased rate of complicated AA, increased hospital stay and increased postoperative complications.
Photocatalytic Degradation of Composites With Magnesium Aluminum Hydrotalcite Derived Metal Oxides and g-C3N4
Authors: Yu Mingwei , Zhang Lianhong , Wen Jie , Zhang Hui , Liu Faping , Lv Yanjun , Zhao Xiaodong
Published: September 2021

The remove of the organic pollutants in water plays an important role on the environmental protection, thus photocatalysis, as an effective method, has been attained much attention to deal with this problem. In this paper, a composite of g-C3N4 and Mg-Al hydrotalcite derived metal oxides was prepared to degrade these organic pollutants by simple calcination and co-precipitation methods. And Mg-Al hydrotalcite derived metal oxides were successfully coated on the surface of g-C3N4. The photocatalytic degradation rate of methylene blue reached 97.3% within 1h under visible light, and the degradation rate constant was 0.0432min-1, which is 3.6 times that of g-C3N4. In the recycling process of the catalyst, the good stability of photocatalytic degradation was found. Though characterization analysis, more active sites are exposed to absorb more organic pollutants on the mater surface in the presence of the interinserted and coated structures of composite materials, and the "face to face" contact structure between 2D materials is formed to promote the separation of photogenerated carriers. In addition, the photocatalytic degradation mechanism of the catalyst was explained by free radical scavenging experiment. The material provides an effective method for removing organic pollutants in water, and has broad application prospects.
Characterization and genome analysis of two novel Aeromonas hydrophila phages PZL-Ah1and PZL-Ah8
Authors: Yu Huabo , Feng Chao , Zhang Liang , Chi Teng , Qi Yanling , Jia Kaixiang , Zhang Yang , Wei Junfeng , Qian Aidong , Sun Wuwen , Shan Xiaofeng , Zhang Lei
Published: September 2021

Aeromonas hydrophila (A.hydrophila) is an opportunistic pathogen of fish-human-livestock, which poses a seriously affects to the development of aquaculture. Phage therapy is considered as a process to alternatively control bacterial infections and contaminations. In this study, the genomes of two Aeromonas hydrophila- specific phages PZL-Ah1 and PZL-Ah8 were isolated, characterized and genomic sequence analyzed. Transmission electron microscopy showed that the two phages had been classified as the member of the Podoviridae family. Both the two phages in this study had relatively narrow host range with lytic activity against Aeromonas spp. strains. However, they could lyse 3 common A.hydrophila strain. As revealed from the whole genomic sequence analysis, PZL-Ah1 and PZL-Ah8 coverd the double-stranded genome of 38,641 bp and 40,855 bp in length, with the GC content of 53.68% and 51.89%, respectively. Through gene comparison in NCBI database revealed that PZL-Ah1 and PZL-Ah8 were 97.67% − 95.51% identical to Stenotrophomonas phage IME15 and Aeromonas Phage T7-Ah. Phylogenetic analysis showed that PZL-Ah8, PZL-Ah1 and other two phages belonged to the same genus. A total of 44 and 52 open reading frames (ORFs) were predicted in the PZL-Ah1 and PZL-Ah8 genome, respectively. In the process of gene annotation, 28 (63.6%) ORFs in PZL-Ah1 and 29 (55.8%) ORFs in PZL-Ah8 were known to functional proteins in NCBI database, while the remaining ORFs were classified as “hypothetical proteins”, whose functions were yet unknown. By comparing, ORF 02, ORF 29 and ORF 04 in PZL-Ah1, ORF24 in PZL-Ah8 were responsible for the host cell lysis. In conclusion, genomic studies of these two novel phages would lay the foundation for expanding the phage genome database and providing good candidates for phage typing applications.
Self-referenced method for the Judd–Ofelt parametrisation of the Eu3+ excitation spectrum
Authors: Ciric Aleksandar , Marciniak Lukasz , Dramicanin Miroslav
Published: September 2021

Judd-Ofelt theory presents a centrepiece in spectroscopy of lanthanides since it explains and predicts 4f absorptions and emissions from only 3 intensity parameters. A self-referenced method for calculating Judd–Ofelt intensity parameters from the excitation spectra of Eu3+-activated luminescent materials is proposed in this study along with a description of the parametrisation procedure and free user-friendly web application. It uses the integrated intensities of the 7F0→5D2, 7F0→5D4, and 7F0→5L6 transitions in the excitation spectrum for calculations and the integrated intensity of the 7F0→5D1 magnetic dipole transition for calibration. This approach allows a simple derivation of the Ω6 intensity parameter, which is difficult to calculate precisely by Krupke’s parametrisation of the emission spectrum and, therefore, frequently omitted in published research papers. Compared to the parametrisation of absorption spectra, the described method is more accurate, can be applied to any material form, and requires a single excitation spectrum.
Mediating Effect of Students' Perception in Programming on the Relationship Between Project Work and College Students' Interest in Programming
Authors: Senior Isaac Ampofo Atta
Published: September 2021

Computer programming has been a subject of debate whether students have interest or not. Students' impressions of their own abilities to program and of programming in general are influenced by their early programming experiences, which play a role in encouraging or discouraging students' interest in computing areas. As a result, project work as a method of teaching has been adopted by many lecturers in teaching computer programming. However, the study sought to assess the mediating influence of students' perception in the relationship between project work and college students' interest in programming. The study used a descriptive survey design. The target population for the study included all Computer Science and Mathematics students in the University of Cape Coast, Ghana. The population for the study was 2,410 students with a sample size of 332. The researcher used a questionnaire to gather the data for studying the issue under investigation. Analysis of the data was done through the use of the PROCESS Macro. The results revealed that the mediating effect of students’ perception in programming on the relationship between project work and college students’ interest in programming account for only 0.34% of the contribution of factors that influence college students’ interest in programming.
Vibration Control of Weakly Rigid Casing Based on Gasbag-rubber Damping Flexible Fixture
Authors: Zhu Xiaohua , Zhang Yao , Li Tian , Dong Liangliang , Tang Junlei , Zhang Shengwei
Published: September 2021

Combustion chamber casing is a key component of aeroengine, because of its poor rigidity, severe chattering occurs during milling, which seriously affects the surface quality and processing efficiency of the casing, and the existence of geometric nonlinear problems in the machining process makes it difficult to predict machining vibration. Therefore, it is of great significance to study the vibration law of thin-walled casing and reduce machining vibration. Aiming at the problem of vibration control of thin-walled casing, this paper proposes a new type of gasbag-rubber damping flexible fixture, which differ from the ordinary rigid fixture, this fixture has adjustable clamping force and good vibration damping ability. The key factors affecting the vibration response of the thin-walled casing are studied through establishing an equivalent dynamic model of the workpiece-fixture system. The research results show that the gasbag-rubber damping flexible fixture can effectively provide support stiffness, which is beneficial to reduce the vibration of the workpiece during processing; According to the actual thickness of different workpieces, the appropriate gasbag pressure is recommended to give play to the vibration damping performance of the fixture; It is recommended that the thickness of the rubber damping block in practice is 8~12mm. The research work in this paper has important guiding significance for the design and use of the gasbag-rubber damping flexible fixture, and provides an effective theoretical prediction for the vibration of the thin-walled casing.
Effects of eight-week progressive resistance training on physical fitness and psychological health in adolescent males
Authors: Afonso José , Sadeghi Masoud , razi Omid , Martins Alexandre , Parnow Abdolhossein
Published: September 2021

Introduction: Physical fitness and psychosocial health might improve through resistance training programs. However, there has been controversy regarding the efficacy of different exercise programs. To compare the effect of 8 weeks’ resistance training with linear and undulating programming on physical fitness and mental health.Methods: 29 healthy and untrained students (age: 16.06±0.83) were randomly divided into three groups: (1) control (n= 6), (2) linear programmed resistance training (LPRT) (n= 12), and (3) undulating programmed resistance training (UPRT) (n= 11). After two weeks of familiarization, 1RM values were obtained. Thereafter, experimental groups attended a resistance training program of 3 sessions per week for 8 weeks. Both groups had a similar plan until the fourth week. Then, intensity was increased up to 70% of 1RM on a weekly basis for the LPRT group, and varied on a daily basis for the UPRT group. Upper- and lower-extremities strength and endurance, balance, speed, explosive-power, lean body mass, general mental health (GSQ) and physical self-concept (PSCQ) were measured.Results: Experimental groups produced significant improvements in physical outcomes, in comparison with controls. There were no improvements in GSQ and PSCQ. There were no statistically significant differences between the two programs.Conclusion: Both linear and undulating programs improved physical fitness of previously sedentary adolescent boys to a similar extent. For practical purposes, as long as loads are individually adjusted, the type of program may not be relevant in beginner practitioners. Furthermore, both models were ineffective in producing changes in the psychosocial variables.
Flowering Biological Characteristics of Camellia weiningensis Y.K. Li.
Authors: Wei Hongli , Gao Chao , Qiu Jie , Long Li , Wang Biao , Yang Lu , Hu Yang
Published: September 2021

This study aimed to investigate the flowering biological characteristics, floral organ characteristics, and pollen morphology of Camellia weiningensis Y.K. Li. These features of adult C. weiningensis plants were observed via light microscopy and scanning electron microscopy (SEM). Pollen viability and stigma receptivity were detected using 2,3,5-triphenyltetrazole chloride (TTC) staining and the benzidine–hydrogen peroxide reaction method. C. weiningensis is monoecious, with alternate leaves and glabrous branchlets. Its flowering period lasts 2 to 4 months, and the flowering time of individual plants lasts ≈50 days, with the peak flowering period from the end of February to the middle of March. It is a “centralized flowering” plant that attracts a large number of pollinators. Individual flowers are open for 12 to 13 days, mostly between 1230 and 1630 hr, and include four to six sepals, six to eight petals, ≈106 stamens, an outer ring of ≈24.6-mm-long stamens, an inner ring of ≈13.4-mm-long stamens, one pistil, and nine to 12 ovules. The flowers are light pink. The style is two- to three-lobed and 16.6 mm long, showing a curly “Y” shape. The contact surface of the style is covered with papillary cells and displays abundant secretory fluid and a full shape, facilitating pollen adhesion. The pollen is rhombohedral cone-shaped, and there are germ pores (tremoids). The groove of the germ pore is slender and extends to the two poles (nearly reaching the two poles). The pollen is spherical in equatorial view and trilobate in polar view. The pollen vitality was highest at the full flowering stage, and the stigma receptivity was greatest on days 2 to 3 of flowering. The best concentration of sucrose medium for pollen germination was 100 g/L. The number of pollen grains per anther was ≈2173, and the pollen-to-ovule ratio was 23,034:1. C. weiningensis is cross-pollinated. Seventy-two hours after cross-pollination, the pollen tube reached the base, and a small part entered the ovary. The time when the pollen tube reached the base after pollination was later than that in commonly grown Camellia oleifera. The results of this study might lay an important foundation for the flowering management, pollination time selection, and cross-breeding of C. weiningensis.
Effects of Freezing-Thawing on Microbial Community Structure in the Soil of Old Apple Orchards
Authors: Wang Haiyan , Zhang Rong , Jiang Weitao , Mao Yunfei , Chen Xuesen , Shen Xiang , Yin Chengmiao , Mao Zhiquan
Published: September 2021

The study here aimed to investigate the effects of pre-winter ditching and freezing-thawing on soil microbial structure in different soil layers of old apple orchards. A total of 30 samples were obtained from 3 Nov. 2016 to 9 Mar. 2017. The relative abundance, alpha diversity, community structure of fungi, and the relationship between environmental factors and microbial community structure were analyzed, and the greenhouse experiments were used for further verification. Results showed that the number of actinomycete and total bacterial colonies decreased, whereas the number of fungi sustained decreased, resulting in a higher bacteria/fungi ratio. The percentage of Fusarium initially decreased, then later increased by 11.38%, 3.469%, 2.35%, 2.29%, and 3.09%. However, Fusarium levels were still 9% lower on 9 Mar. 2017 that on 3 Nov. 2016. Both the abundance and diversity of the community were higher in the upper soil than in the lower. The main environmental factor contributing to the percentage of Fusarium change was average temperature (AT), although highest temperature (HT) and water content (WC) also had an impact. The Malus hupehensis Rehd. seedlings growing in lower soil were more vigorous than that in upper soil. In sum, pre-winter ditching and freezing-thawing in old apple orchards can reduce the abundance percentage of harmful Fusarium and promote the growth of M. hupehensis Rehd. seedlings.
Formação Docente na Área Contábil: Contribuições da Disciplina de Metodologia do Ensino oferecida na Pós-Graduação Stricto Sensu
Authors: Silva Cris Ferreira da , Ferreira Layne Vitória , Leal Edvalda Araújo , Miranda Gilberto José
Published: September 2021

O objetivo do presente estudo foi investigar a contribuição da disciplina de Metodologia do Ensino, oferecida por um Programa de Pós-Graduação stricto sensu em Ciências Contábeis, localizado em Minas Gerais. A pesquisa foi realizada com os alunos de uma instituição pública brasileira, a amostra é composta de 27 pós-graduandos que participaram da  entrevista narrativa. Os resultados apontaram que a disciplina de Metodologia do Ensino contribui para a formação docente dos alunos que estão iniciando a carreira, propicia conhecer conteúdos relevantes referentes à didática e possibilitou aos pós-graduandos conhecerem e aplicarem diferentes metodologias de ensino. Para aqueles que já atuam na docência, a disciplina promove uma reflexão sobre métodos de ensino e o aperfeiçoamento das técnicas utilizadas no ambiente educacional. Percebe-se que a formação docente exige o aprimoramento contínuo das estratégias de ensino e discussões sobre os temas que envolvem conteúdos como: planejamento pedagógico, currículo e processo de avaliação, dentre outros. Os resultados sugerem a necessidade de sistematização da formação docente, notadamente por meio da obrigatoriedade de disciplinas de caráter didático-pedagógico.
Из синтаксе падежа у српским говорима околине Шипова
Authors: Цукут Слађана М.
Published: September 2021

У овом раду издвојене су фреквентне појаве из падежне проблематике које обиљежавају српске говоре околине Шипова на југозападу Републике Српске и западу Босне и Херцеговине, те појединачне конструкције које се не јављају често, али могу упутити на везе са ближим или даљим сродним говорима. И једним и другим конструкцијама заједничко је то да у савременом српском језику углавном већ имају статус архаизама, а неке од њих никад и нису биле стандардне.
Јечам и калопер или Рани јади у Башти сљезове боје. Три примјера тематизовања породице у новијој српској књижевности
Authors: Поповић Ранко В.
Published: September 2021

Предмет рада су три и жанровски и тематски специфична дјела чији су аутори, према редослиједу књига у наслову, Рајко Петров Ного, Данило Киш и Бранко Ћопић. Истраживачко-интерпретативни интерес усмјерен је на топос породице у овим дјелима, те његове функције и значења у три различита прозна умјетничка текста које осим тематике и специфичне приповједне перспективе повезује и висок степен поетизације прозног исказа.
Једна интертекстуалност или како је Матовић прочитао Христића
Authors: Копривица Тијана М.
Published: September 2021

Намера нам је да у овом раду покажемо на које све начине песник Петар Матовић (1978) у збиркама поезије Кофери Џима Џармуша (2009), Одакле долазе даброви (2013), Из срећне републике (2017), односно у циклусима Нове песме из избора песама Не хлеб, већ морфијум (2019) и Линија фронта (2019) остварује интертекстуалне везе са стваралаштвом Јована Христића (1933–2002). Полазећи од теоријског утемељења појма интертекстуалности, затим од Матовићевих песама које експлицитно призивају Христићево дело, и потом трагајући за мотивима, поступцима и идејама који имплицитно откривају Матовићеве интертекстуалне везе са Христићем, тежићемо да прикажемо изворе из којих Матовић црпи део своје песничке инспирације. Осим тога, указаћемо и на наслојавање шире традиције које се одиграва у процесу одабира књижевног наслеђа, посредством интертекстуалних веза које Матовић и Христић остварују са делима грчког песника Јоргоса Сефериса – Из бродског дневника I, Из бродског дневника II, Из бродског дневника III.
A alfabetização e a heterogeneidade de conhecimentos sobre a escrita no Brasil e na França
Authors: Torres da Silva Nayanne Nayara , Borges Correia de Albuquerque Eliana
Published: September 2021

A presente investigação analisou as práticas de professoras do 1º ano do Ensino Fundamental do Brasil e da França no atendimento à heterogeneidade de conhecimentos sobre a escrita alfabética dos alunos, assim como os diferentes níveis de apropriação do sistema de escrita das crianças de ambas as turmas ao início e final do ano letivo. Os procedimentos metodológicos envolveram observações e entrevistas, realizadas com as professoras, diagnoses de escrita de palavras, aplicadas aos alunos brasileiros, e a análise dos cadernos de classe dos aprendizes franceses. Os dados da investigação, tratados por meio da análise temática de conteúdo, evidenciaram diferenças significativas nas aprendizagens dos alunos brasileiros e franceses, relacionadas, entre outras coisas, à forma como as docentes lidavam com os diferentes conhecimentos das crianças no que se refere à apropriação da escrita alfabética. A professora brasileira tinha mais dificuldades para  avaliar os conhecimentos dos seus alunos e tratar a heterogeneidade da sua classe.
Interpretação educacional e as políticas inclusivas e bilíngues
Authors: Bonfim Tatiane Cristina , De Oliveira Martins Vanessa Regina
Published: September 2021

Esse artigo compartilha alguns resultados sobre a educação bilíngue de surdos e a atuação do intérprete educacional (IE) nos anos iniciais, apontados em uma pesquisa de mestrado realizada em um programa de pós-graduação em educação especial (PPGEEs). Analisamos a transposição alguns discursos de verdade sobre a educação de surdos e suas implicações nas práticas cotidianas efetivas por profissionais IE. Tratou-se de uma pesquisa-descritiva, estudo de caso, de abordagem qualitativa. Os dados foram balizados pelos Estudos Surdos e pelas filosofias da diferença em Michel Foucault. Verificamos que as práticas cotidianas dos IE ainda refletem um paradoxo educacional inclusivo muito complexo: avistam-se práticas que apontam na direção de uma educação de/com surdos, portanto, alinhadas à resistência surda e em outros momentos veem-se práticas voltadas para uma educação para surdos, pautada na lógica do sujeito ouvinte, vinculando-se ao caráter normativo-corretivo-patológico.
Turismofobia em Barcelona: um tema (que era?) emergente
Authors: Soares Oliveira Josefa Laize , Da Silva Neves Carla Carolina , Panosso Netto Alexandre , Ferraz Severini Valéria
Published: September 2021

Os excessos do fenômeno turístico giram em torno de um paradigma social. À medida em que se insere nas dinâmicas que caracterizam uma cidade contemporânea, este campo de atuação e de estudos tornou-se sinônimo de expectativas sobre momentos memoráveis (para quem viaja) e de desenvolvimento socioeconômico (para quem reside em localidades turísticas). Em contrapartida, os efeitos ocasionados pela massificação dos destinos quebram as formas de alcance das projeções positivas, ainda que os interesses entre os atores envolvidos sejam distintos. O objetivo deste artigo foi analisar estes efeitos na rotina de residentes da cidade de Barcelona, na Espanha, bem como aspectos da hostilidade a turistas. Até o final do ano de 2019 e início de 2020, a cidade estava no centro das discussões em torno de um fenômeno denominado turismofobia. Na compreensão de tais questões, foram consultados em profundidade 24 artigos científicos disponíveis na literatura entre turismo, hospitalidade e política. Por meio de análise qualitativa, os resultados revelam que ações para o desenvolvimento do turismo precisam ser repensadas e adaptadas às dinâmicas da turismofobia. Assim, o atual cenário da saúde pública global, em decorrência da pandemia induzida pelo Covid-19, trouxe novas reflexões entre discussões sobre políticas rigidamente sustentáveis e a dinâmica pré-estagnação das viagens.

Palavras-chave: Barcelona. Turismofobia. Turismo de Massa. Gentrificação. Overtourism. Hostilidade.
Dedicated COVID-19 Resource Center in Radiology Journals: Its Citation
Metrics and Altmetrics Impact
Authors: Al-Ryalat Nosaiba , Malkawi Lna , AlRyalat Saif Aldeen
Published: September 2021

Background:

Since the emergence of coronavirus disease 2019 (COVID-19), several
journals have established a dedicated resource center for all the articles published on COVID-19.
Our study compared the altmetric impact captured by articles published in journals having a
COVID-19 resource center.

Methods:

We used the Web of Science database to assess radiology journals publishing the most
common articles on COVID-19. We used the dimensions database to assess citations received and
altmetric attention score for each article. For each article, we extracted several citations received
and altmetric attention scores. To account for the variation in strength and exposure between included
journals, we adopted a normalization strategy and regression analysis in our statistical analysis.

Results:

A total of 494 articles were included in the current assessment, including 334 (67.6%) articles
published in journals with the dedicated COVID-19 resource center, including European radiology,
American Journal of Roentgenology, Radiology, and Journal of the American college of radiology,
while European Journal of Nuclear Medicine and Molecular Imaging, Academic Radiology
did not have COVID-19 resource center. Journals with COVID-19 resource center had a mean normalized
altmetric attention score of 0.38 higher (95% CI 0.25 to 0.50; p< 0.001) and a mean normalized
citation count of 6.73 higher (95% CI 3.99 to 9.48; p< 0.001) than those without
COVID-19 resource center.

Conclusion:

Radiology journals that provided COVID-19 articles in a dedicated resource center
within its homepage had greater attention and higher citation for their COVID-19 articles than journals
that did not have such a dedicated resource center.
Analisis kebijakan penempatan ahli gizi sebagai tenaga keolahragaan Indonesia
Authors: Penggalih Mirza Hapsari Sakti Titis , Trisnantoro Laksono , Sofro Zaenal Muttaqqien , Kusuma Mutiara Tirta Prabandari Lintang , Dewinta Mustika Cahya Nirmala , Niamilah Ibtidau , Anastasia Meta , Susila Edi Nurinda
Published: September 2021

Peran ahli gizi sebagai tenaga keolahragaan pada dasarnya merupakan mandat hukum dari Undang-Undang No. 3 Tahun 2005 tentang Sistem Keolahragaan Nasional, khususnya Pasal 63 yang menyebutkan bahwa ahli gizi merupakan salah satu tenaga keolahragaan. Pada praktiknya, implementasi peran ahli gizi sebagai tenaga keolahragaan di pusat pembinaan atlet masih belum optimal. Keterbatasan sumber daya manusia dan anggaran, serta belum adanya kebijakan operasional yang mengatur tentang penempatan ahli gizi di pusat pembinaan atlet menjadi beberapa kendala yang perlu solusi. Pengkajian ini menggunakan pendekatan kualitatif dengan melakukan studi dokumen terhadap delapan peraturan yaitu 1 undang-undang, 1 perpres dan 6 permen. Seluruh dokumen kebijakan tersebut selanjutnya ditetapkan pasal-pasal kritis yang dianalisis lebih lanjut untuk diberikan diskripsi penjelas, analisis mendalam pasal demi pasal, perumusan rekomendasi dan output kebijakan. Pengkajian ini telah memperoleh Ethical Clearance dari Komisi Etik FKKMK UGM dengan nomor: KE/FK/0292/EC/2020 pada tanggal 10 Maret 2020. Kajian terhadap Undang – Undang Nomor 3 Tahun 2005 dan peraturan hukum pendukungnya menunjukkan bahwa peran ahli gizi memiliki urgensi tinggi dalam pembinaan atlet. Namun demikian masih perlu kebijakan operasional yang mengatur tentang penempatan ahli gizi sebagai tenaga keolahragaan, meliputi tugas dan wewenang, serta standar kompetensi dan sertifikasi ahli gizi sebagai tenaga keolahragaan.
The effect of brain vitalization exercise on muscle strength and endurance in people with dementia
Authors: Fitri Mustika , Fauziyah Ajeng , Nur Hana Astria
Published: September 2021

This study aims to determine the effect of brain vitalization exercise on muscle strength and endurance in people with dementia. The pre-experimental method with a one-group pretest-posttest design was used in this study. Purposive sampling technique was used in this study, then a sample of 31 people with dementia was obtained from a population of 78 people in Cibeunying Kidul District. The Arm Curl Test instrument is used in research that aims to measure arm muscle strength and Chair Stand Test which aims to measure leg muscle endurance. The data analysis technique in this study used Paired Sample T Test using the help of SPSS version 25 software. Based on data analysis, the results showed that the muscle strength obtained sig. 0.000 < 0.05 and on the durability of sig. 0.000 < 0.05 so it can be concluded that there is a significant effect of brain vitalization exercise on muscle strength and endurance in people with dementia.