bluuebunny/crossref_metadata_2025 huggingface dataset:
Klasifikasi Penyakit Diabetes Menggunakan Metode SVM Dan KNN
Authors: Aswin Ardiansyah  , Enos C.O.Telaumbanua  , Aron S. Gultom  , Angelita A. S. M. Limbong
Published: August 2024

Diabetes is a disease caused by high blood sugar levels and impaired insulin production in the body. Although it is not a contagious disease, in fact, many Indonesians suffer from diabetes. In fact, according to the North Sumatra Health Department, the prevalence of diabetes in Indonesia is estimated to reach 21.3 million people by 2030. As technology develops, machine learning has helped many health practitioners in dealing with diabetes, one of which is modeling with SVM and KNN. The application of this algorithm aims to create a model that is able to classify diabetes in patients based on data of diabetes factors such as age, weight, blood pressure, blood sugar levels, etc. The model that has been built is then evaluated for its performance with a confusion matrix, with the evaluation results of the SVM model being better than KNN with an accuracy of 100% for the SVM model and an accuracy of 96% for the KNN model.
Analisis Pengendalian Kualitas Produk Midsole Dengan Metode Seven Tools Dan Failure Mode Effect Analysis Pada PT.XYZ
Authors: Paradika Rossadi  , Sumiati Sumiati
Published: August 2024

PT. XYZ is a company operating in the shoe industry. In the midsole production process, defects such as burning defects, tear defects, bubble defects and dirty. The aim of this research is to determine the proportion of defects that most frequently occur and the factors that cause defects and to provide suggestions for improving the quality of the Midsole. The method used is Seven tools and Failure Mode Effect Analysis (FMEA). Seven tools include check sheets, statistics, histograms, Pareto diagrams, scatter diagrams, control charts, and fishbone diagrams. Then continue the FMEA analysis to get suggestions for corrective actions. Based on the results of Seven Tools research, it is known that the most dominant defects in the midsole are burnt (38%), then dirty (24.4%), bulging (20%), and torn (17.4%). 6%) ). Based on the results of the Failure Mode Effect Analysis (FMEA) research, it is known that the highest cause of problems with RPN 343 is uneven spraying of the Mold Release Agent. Suggestions for improvement that can be submitted are: Conduct training to workers on how to spray MRA according to standards and determine rest time limits so that the injection machine does not overheat.
Serat Tanaman Mendong Sebagai Fiber Jacket Untuk Perkuatan Kolom Beton Bertulang Pasca Kerusakan Bangunan
Authors: Dwi Sulistiyawati  , Noor Mohammad Hatta  , Fariz Wahyu Setiawan  , Arny Wasis Enggarriny  , Agustinus Sungsang Nana Patria
Published: August 2024

Column collapse can be overcome by increasing the nominal strength of the cross section, one of which is by strengthening using FRP (Fiber Reinforced Polymer). This research will focus on the effect of using mendong plant fiber as a fiber jacket for strengthening reinforced concrete columns after building damage. Starting from material testing, mix design calculations, making test objects and testing test objects. There are 3 variations of test objects, namely concrete without a layer of Mendong fiber, concrete with 2 layers of Mendong fiber and concrete with 4 layers of Mendong fiber. The number of test objects was 15 concrete cylinders and 6 reinforced concrete columns. Reinforced concrete column specimens were subjected to axial testing to obtain the maximum axial load. Based on the test results, it was found that the average axial strength of reinforced concrete columns without mendong fiber blanket was 120.03 kN, the average axial strength of post-damaged reinforced concrete columns with 2 layers of mendong fiber blanket was 134.46 kN and the average axial strength of post-damaged reinforced concrete columns damaged with a 4-layer mendong fiber blanket of 144.83 kN. The greater the number of layers of mendong fiber, the axial strength of the post-damaged reinforced concrete column will increase with an increase of 12.02% for 0 layers to 2 layers, and 7.71% for 2 layers to 4 layers. Based on the results of this research, mendong fiber can be used as an alternative to fiber jacket for reinforcing reinforced concrete columns after building damage.
Analisis Tingkat Kecacatan Produk Dengan Seven Tools Dan Failure Mode Effect Analysis Di PT. Selatan Jadi Jaya
Authors: I Dewa Gede Rama Putra  , Sumiati Sumiati
Published: August 2024

PT. Selatan Jadi Jaya is a company that produces lead acid batteries for Automotive Car Batteries. During production, problems often arise, namely a fairly high level of product defects.  Defects appearing in the burning process include defects in melted tin, burned connectors, bent plates, and torn separators. The purpose of this study is to determine the level of product defects and provide suggestions for improving the quality of battery batteries. Based on the above problems, analyzing the level of defects can use the Seven Tools method and improvement efforts using Failure Mode and Effect Analysis (FMEA). Based on the results of research on Seven Tools that the dominant defect is Connector Burning with a percentage of (33%), then followed by Plate Bent by (26%), then Melted Tin by (24%), and Torn Separator by (17%). Based on the results of the Failure Mode and Effect Analysis research, it is known that the highest RPN value is 200 on tin melt defects.  The recommendation for improvement is to adjust the size of the fire according to the procedure.
Perbandingan Kinerja Model RNN, LSTM, dan BLSTM dalam Memprediksi Jumlah Gempa Bulanan di Indonesia
Authors: Roni Merdiansah  , Khofifah Wulandari  , Mentari Hasibuan  , Yuyun Umaidah
Published: August 2024

Earthquakes are natural phenomena that frequently occur in Indonesia. To identify and predict the level of earthquake activity, effective prediction methods are needed. In this study, we employed a Recurrent Neural Network (RNN) to predict the average number of earthquakes that occur each month in Indonesia. This research utilized a large amount of historical earthquake data in Indonesia. We divided this data into training and testing sets to train and evaluate our prediction model. Additionally, we used Mean Absolute Error (MAE) and Mean Squared Error (MSE) as evaluation metrics to measure the accuracy of our model's predictions. The results showed that using Long Short-Term Memory (LSTM) units with a Bidirectional (BLSTM) configuration, which is a part of RNN, provided accurate predictions regarding the average number of earthquakes per month in Indonesia. We achieved an MAE of 0.0668 and RMSE of 0.0858, indicating a good level of accuracy in predicting the average number of earthquakes. This research contributes significantly to the understanding and prediction of earthquake activity in Indonesia. The use of deep learning techniques in RNN can provide accurate and reliable prediction outcomes for earthquake mitigation and risk reduction efforts in Indonesia.
Kajian Efektifitas Penggunaan Abu Sekam Padi sebagai Bahan Stabilisasi pada Tanah Lempung terhadap Nilai CBR
Authors: Vella Anggreana  , Rasyidah Rasyidah
Published: August 2024

One type of soil that has many problems in a construction development is clay soil. Clay soil originating from Jl. Abdul Rahman Hamid, Tenayan Raya District, Pekanbaru has a problem where there are cracks and waves on the road due to non-uniform subsidence. To deal with problems in the soil one way that can be done is by stabilization. The purpose of this study was to determine to determine the effect of a mixture of rice husk ash on the CBR value and to find the optimal mixture. The research uses the laboratory test method, by testing CBR on variations of the rice husk ash mixture amounting to 4%, 7%, and 10% of the dry weight of the soil with unfermented conditions, 7 days of incubation and 4 days of soaking. The effect of using rice husk ash on the value of CBR in unfermented conditions increased in the 4% and 7% rice husk ash mixture, but decreased in the 10% rice husk ash mixture. The influence of the use of rice husk ash mixture on 7-day fermentation increases the CBR values. Whereas in immersion conditions, the CBR value tends to decrease with increasing rice husk ash levels. The optimal mixture in CBR occurred in a mixture of 10% rice husk ash with a 7-day fermentation condition of 12.85%. Thus, it is concluded that the use of the percentage of the mixture as well as the length of the soaking and soaking days used can affect the CBR value of the soil.
Evaluasi Program Pengurangan Emisi Limbah Industri Dalam Upaya Mencapai Target Perlindungan Lingkungan
Authors: Maghrobi Ilham Rahmansyah  , Mohammad Yahya Nur Firdaus  , Diota Cahya Muhajir  , Moch. Bayu Septian  , Denny Oktavina Radianto
Published: August 2024

Evaluation of industrial waste emission reduction programs is a critical step in efforts to achieve environmental protection targets. These programs aim to reduce the negative impact of industrial pollution on the environment and human health. This research aims to evaluate the effectiveness of the industrial waste emission reduction program that has been carried out in an effort to achieve the environmental protection targets that have been set. The journal research method with the literature review method is an approach used to collect, evaluate, and synthesize information from various relevant literature sources. The effectiveness of industrial waste emission reduction programs is very important to maintain environmental sustainability. These programs aim to reduce the negative impact of industrial pollution on the environment and human health. Evaluation of the effectiveness of these programs is crucial to ensure that emissions reduction efforts achieve the desired results (Ikhtiarin et al, 2023). In this evaluation, it is necessary to consider an analysis of the type of emissions targeted, external factors that influence the effectiveness of the program, and the social and economic impacts of the program. Apart from that, the application of technology and innovation to reduce emissions and industry compliance with emission reduction programs are also important factors. Community participation and involvement also plays a role in supporting the success of industrial waste emission reduction programs, by increasing awareness and active participation of the community in efforts to reduce waste emissions.
Prototype Monitoring Dan Kontrol Kualitas Nilai Ph Air Pada Kapal
Authors: Galuh Ayu Hapsari  , Sri Mulyanto Herlambang  , Arleiny Arleiny
Published: August 2024

Water is an important resource in daily life on board a ship. pH is a measure of the acidity or alkalinity of a solution, including water. The pH value ranges from 0 to 14, where a pH of 7 indicates a neutral solution, a pH value of less than 7 indicates an acidic solution, and a pH value of more than 7 indicates a basic solution. Therefore, it is important to have an effective monitoring and control system to ensure the pH value is safe and meets applicable standards. The method used in this research uses an experiment using an ESP32 microcontroller and the parameters used are a pH sensor to determine the pH value of the water on board the ship. The sensor provides data input to the ESP32. The data is processed and displayed on the LCD. In this system, if the pH of the water does not meet the standard, the ESP32 drives pump 1 or 2 to flow the acid or base solution. Testing on tools made to detect the pH value of water. The purpose of making this tool is to monitor and control water quality in order to avoid dangers that may arise due to exposure to water that is contaminated or with an inappropriate pH. This system can function well because there is an average error of 0.24% in testing between the pH sensor and the pH meter.
Rancang Bangun Sistem Monitoring Air Tawar Yang Berkualitas Pada Fresh Water Generator Di Atas Kapal MT. Alpha Point
Authors: Andhika Bintang Narottama  , Antonius Edy Kristiyono  , Akhmad Kasan Gupron
Published: August 2024

Water is the most abundant thing on earth. However, in reality, the water on ships is not always considered consumable. This is caused by the FWG (Fresh Water Generator) auxiliary machine processing process. FWG is a ship auxiliary engine that produces fresh or salt water through a distillation process. FWG carries out distillation using a heat source from the jacket for the evaporation process to produce fresh water. The accuracy of the salt content produced through FWG is not yet known. If processed FWG products whose salt content is unknown are still consumed, it will have a negative impact on health, such as: kidney failure and the risk of developing kidney stones. Based on this problem, a tool was designed to monitor the salt content of processed FWG on board ships so that it could be used by all crew members and passengers. According to quality standards, the salt content that can be consumed by humans is below 50 ppm, with a pH between 5.0 to 7.5 and a turbidity of between 5 and 25 NTU. By designing this tool, we will be able to monitor the suitability of FWG fresh water so that it can be consumed on board. With the help of LCD, it will be able to help provide information regarding monitoring results of water quality. In testing this tool, the pH sensor, turbidity sensor and salinometer conductivity sensor will help to test the suitability of fresh water.
Pengaruh Variasi Bentuk Permukaan Piston dengan Campuran Bahan Bakar Ethanol Terhadap Emisi Gas CO dan HC pada Motor Bensin 100CC
Authors: Yulius Dicky Prasetya  , Sugeng Hadi Susilo
Published: August 2024

The high demand for motorised vehicles in Indonesia has resulted in an increased demand for fossil fuels, which has led to a decrease in their availability. One alternative solution is to utilise ethanol as fuel. The use of ethanol can increase the octane value of the fuel, but this requires adjustments to the engine's compression ratio. One way to increase the compression ratio is to modify the piston surface. By applying alternative fuels and modifying the piston surface, it is expected to reduce CO and HC exhaust emissions. This study aims to determine the effect of various piston surface shapes on CO and HC exhaust emissions when using pertalite and pertalite fuel mixture with ethanol. In this study, the test used a gas analyser to obtain CO and HC emission data. The research data is presented in tabular form and analysed using the two-way ANOVA method and graphs. The results of using variations in piston surface and fuel mixture showed the highest reduction in CO emissions of 65.9% at RPM 6000 and HC emissions of 48.5% at RPM 3500.
Pengaruh Sistem Informasi terhadap Kualitas Laporan Keuangan pada Kantor KPP Pratama Bireuen
Authors: Handry Eldo
Published: August 2024

This research aims to determine the effect of implementing information systems on the quality of financial reports at the KPP Pratama Bireuen office. This research uses quantitative descriptive methods, with primary and secondary data sources. Data collection techniques use questionnaire and documentation methods. The results of this research show that the implementation of information systems has a significant effect of 70,2% on the quality of financial reports.
Analisis dan Mitigasi Risiko dalam Pengadaan Menggunakan Pendekatan House of Risk pada Perusahaan Jaringan Broadband
Authors: Divazanna Illaritzqi  , Silvi Istiqomah  , Abduh Sayid Albana
Published: August 2024

In 2023, the number of internet users in Indonesia significantly increased to 212.9 million, highlighting the importance of reliable network infrastructure. A broadband network company operating in the telecommunications sector faces various risks in its procurement process of materials and services that are essential to support its operations. Risks such as material delays and specification mismatches present challenges that must be carefully managed. This study employs the House of risk (HOR) method to analyze 19 risk agents and risk events that could potentially impact the procurement process, focusing on five primary risk agents. The proposed preventive actions, particularly through effective communication, are expected to mitigate the impact of risks in the procurement process within the broadband network company.
Pengembangan Aplikasi Simasjid Menggunakan Metode Extreme Programming
Authors: Bagas Ardianto  , Jaroji Jaroji  , M.Asep Subandri
Published: August 2024

The annual qurban ritual is performed by Nurul Huda Mosque, although a recurring activity, it often encounters challenges in its execution. Issues such as manual participant registration using books and records, non-transparent meat distribution, and the use of traditional paper-based coupon systems for persistent meat allocation. To address these challenges, this study aims to develop a web-based Simasjid application with qurban management features and examine its impact on congregants and qurban participants.The research focuses on the implementation of the Extreme Programming method for developing the Simasjid application. Extreme Programming, as an Agile approach, provides a flexible and adaptive software development model. This method accommodates evolving user requirements and includes stages such as planning, design, coding, and testing.
ABOUT THE BUKHARA COINS IN THE “YANGI SANGANAK” TREASURY OF THE 15TH - EARLY 16TH CENTURIES
Authors:   Doctor of Philosophy (PhD) in History, Senior researcher of the State Museum of the History of the, Normurodov Dilmurod , Kholova Nargis ,   Head of the department of “Funds and Archives”, The State Museum of the History of the Timurids of the Academy of Sciences of the Republic of Uzbekistan
Published: August 2024

This article is dedicated to the description and analysis of 364 Bukhara minted coins out of 1810 copper coins found in “Yangi Sanganak” neighborhood, Parkent district, Tashkent region in 2021, and these coins consist of 6 types. It is noted that they were minted in 1428-1429 under Mirza Ulugbek, at the end of the 15th century during the reign of Timurid Sultan Ahmad, Boysungur Mirza, and during the first decade of the 16th century under Muhammad Shaibani Khan. ‎
Monitoring Application in Academic Evaluation for Web-Based Teacher Performance Assessment at SMA IT Imam Syafi'i
Authors: Veza Okta
Published: August 2024

The design of the Web-Based Teacher Performance Assessment Monitoring Application at SMA IT Imam Syafi'i is an application to support the performance of related agencies. Lack of data collection and the absence of supporting applications and data that are still stored in archives and computers manually. This system is designed based on website using html, css programming language and MySQL database. While the development of the research system uses the RAD (Rapid Application Development) method with the stages of requirements, workshop design, and implementation. This application serves as a method for determining the application of monitoring techniques in the academic assessment of teacher performance. With this designed system, it will be easier for agencies to monitor the academic assessment of teacher performance. And the need to make a teacher performance evaluation report.
Knowledge of Covid 19 and Compliance with Preventive Measures in Asaba Delta State, Nigeria
Authors:   Department of Community Medicine, Delta State Primary Healthcare Development Agency, Delta State Nigeria., Orofuke Ngozi G. , Ofonakara Uzochukwu ,   Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Alex Ekwueme Federal University Ndufu-Alike Ikwo, Ebonyi State, Nigeria., Elusoji Christiana I. ,   Department of Nursing Sciences, Benson Idahosa’s University, Benin City. Edo State, Nigeria, Ofili Charles C. ,   Department of Community Medicine, Delta State Primary Healthcare Development Agency, Delta State Nigeria., Otutu Michael O. ,   Department of Community Medicine, Delta State Primary Healthcare Development Agency, Delta State Nigeria., Ohanme Eugene O. ,   Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Alex Ekwueme Federal University Ndufu-Alike Ikwo, Ebonyi State, Nigeria.
Published: August 2024

Background: The 2019 COVID-19 pandemic has caused global trepidation and anxiety, prompting urgent measures like hygiene, isolation, and social distancing. However, cultural differences in knowledge and compliance with preventive measures persist. Study design: A survey of 589 volunteers in Asaba, Nigeria, evaluated Covid-19 compliance and prevention techniques, focusing on demographic characteristics, knowledge, awareness, compliance rate, and awareness-affecting factors. Methods: This study explored knowledge of COVID-19 and compliance with preventive measures among members Umuagu, Umuaji and Akwebulu communities Asaba, Delta State, Nigeria, using oral and written interviews. Data were sourced from 589 persons comprising 30 household heads age 18 years and above. Data were analyzed statistically anglicized thematically Result: The study found that 99.5% of respondents had knowledge of COVID-19, with internet/social media and TV being the main sources of information. 82.3% believed everyone should wear face masks, and most protective measures included proper hygiene, self-isolation, face masks, and prayers. However, 52.1% felt the government was not doing enough to curb the pandemic, and poor knowledge negatively affected compliance with preventive measures. Conclusion: To improve knowledge on the coronavirus pandemic, an accurate information dissemination strategy to ensure compliance with preventive measures is recommended.
Percepatan Pengadaan Jembatan Gantung sebagai Infrastruktur Penghubung antar Desa melalui e-Purchasing
Authors: Zakariya Ali , Priyadi Panji Arrie , Widhatra Hendra
Published: August 2024

Negara Indonesia memiliki wilayah dominan berkontur pegunungan dengan sungai yang membelah mengakibatkan banyaknya akses pedesaan yang terisolir. Pembangunan infrastruktur jembatan gantung pejalan kaki dapat menjadi penghubung antar Desa sesuai dengan visi misi Presiden Republik Indonesia 2019-2024 dalam membangun daerah tertinggal, terdepan, dan terluar dalam rangka Negara Kesatuan. Pada tahun 2022, pengadaan jembatan gantung pejalan kaki di Direktorat Pembangunan Jembatan, Direktorat Jenderal Bina Marga telah menggunakan sistem e-purchasing melalui e-katalog sektoral LKPP menggantikan sistem lelang. Penggunaan e-purchasing di Kementerian Pekerjaan Umum dan Perumahan Rakyat bertujuan untuk menerapkan prinsip pengadaan dan mengakomodir kemajuan teknologi. Penerapan sistem ini juga didorong oleh Peraturan Presiden Nomor 16 Tahun 2018 beserta turunannya. Penelitian ini mengungkapkan hubungan antara perubahan sistem pengadaan terhadap durasi pengadaan. Perubahan sistem menjadi e-purchasing mengakibatkan penyederhanaan business process pengadaan jembatan gantung pejalan kaki dari semula melalui sistem lelang dan tahapan desain menjadi sistem pemilihan penyedia melalui e-katalog dengan desain telah terstandar. Penyederhanan ini memangkas durasi pengadaan dari sebelumnya lebih dari 5 (lima) bulan menjadi kurang dari 4 (empat) bulan. Selain itu, sistem e-purchasing memungkinkan keikutsertaan penyedia barang semakin banyak dengan peningkatan produktifitas mencapai 0.9 unit/hari. Dengan menurunnya durasi pengadaan maka akan berdampak pada percepatan pemerataan infrastruktur di pelosok daerah.
Kajian Perkembangan Honorarium bagi Pejabat Fungsional Pengelola Pengadaan Barang/Jasa berdasarkan Peraturan Menteri Keuangan tentang Standar Biaya Masukan Tahun Anggaran 2019-2024
Authors: Nugroho Sunu Ardhi
Published: August 2024

Dalam mendukung pelaksanaan kegiatan pengadaan barang/jasa pemerintah yang bersih, efektif dan efisien, sangat diperlukan sumber daya manusia (SDM) yang profesional, berkompeten dan berintegritas. Untuk mendorong profesionalisme tersebut, diperlukan adanya imbalan (reward) berupa honorarium yang memadai, sesuai dengan beratnya beban tugas dan risiko yang disandang. Seiring dengan berlakunya Peraturan Presiden (Perpres) Nomor 16 Tahun 2018 tentang Pengadaan Barang/Jasa Pemerintah yang diubah dengan Perpres Nomor 12 tahun 2021, tugas dan fungsi pengelolaan pengadaan barang/jasa dilaksanakan oleh Pejabat Fungsional (JF) Pengelola Pengadaan Barang/Jasa (PBJ). Tulisan ini akan mengkaji besaran honorarium bagi Pejabat Fungsional Pengelola PBJ berdasarkan Peraturan Menteri Keuangan (PMK) tentang Standar Biaya Masukan (SBM) dari dari tahun 2019 hingga 2024. Berdasarkan hasil analisis tersebut, penulis menemukan fakta bahwa honorarium bagi Pejabat Fungsional Pengelola PBJ berdasarkan PMK tentang SBM tahun 2019-2024 masih sama nominalnya, meskipun terdapat relaksasi persyaratan seperti jumlah paket minimal yang dikerjakan namun terdapat batas maksimal honorarium dalam satu tahun. Kemudian fakta di lapangan menunjukkan bahwa terdapat ketimpangan pendapatan antara Pejabat Fungsional Pengelola PBJ dibandingkan dengan pegawai non JF Pengelola PBJ yang masih berperan dalam pengelolaan pengadaan barang/jasa. Hal ini menunjukkan bahwa pendapatan yang diterima dianggap belum memadai dan tidak proporsional dengan tugas dan tanggung jawabnya meskipun telah diberikan kenaikan kelas tunjangan kinerja dan kenaikan tunjangan fungsional. Diperlukan kebijakan relaksasi pengaturan honorarium untuk menunjukkan keberpihakan pemerintah dalam mewujudkan Pengelola PBJ yang profesional, diantaranya relaksasi jumlah paket minimal yang dikerjakan, batas maksimal tambahan honorarium dalam satu tahun, kenaikan kelas jabatan tunjangan kinerja dan kenaikan tunjangan fungsional dalam jumlah yang signifikan.
Synthesis of A New Thiadiazole-Benzodioxole Derivative, Investigation of Acetylcholinesterase Inhibition with In Vitro and In Silico Studies
Authors: Peçe Göktaş Sare , Osmaniye Derya , Levent Serkan , Sağlık Özkan Begüm Nurpelin , Göktaş Bünyamin , Uslu Harun , Özkay Yusuf
Published: August 2024

Alzheimer’s disease is a progressive and degenerative brain disease that negatively affects people’s lives and reduces cognitive and sensory human functions. Today, there are active ingredients that work on Alzheimer’s disease, containing benzodioxole and thiadiazole rings. Acetylcholinesterase terminates neurotransmission in the nervous system and leads to the accumulation of acetylcholine, overstimulation of various receptors and consequent impairment of neurotransmission. Thiadiazole and benzodioxole rings are compounds that exhibit a wide range of biological activities, especially known to be effective on acetylcholinesterase. A new compound containing benzodioxole and thiadiazole rings was designed, synthesized and its chemical structure was revealed using spectroscopic methods such as HRMS, 13C-NMR and 1H-NMR. Acetylcholinesterase inhibition activities were investigated using in vitro methods. To elucidate the acetylcholinesterase inhibition of compound 4a, it was subjected to in silico insertion procedure with 4EY7. Compound 4a exhibited 0.114±0.005 µM against AChE. The above data is compared with data for donepezil (0.0201±0.0014 µM), the reference compound in our study.
Synthesis of new 1,3,4-thiadiazole derivatives, investigation of their AChE effects
Authors: Cebeci Ayşe Nur , Osmaniye Derya , Sağlık Özkan Begüm Nurpelin , Kaplancıklı Zafer Asım
Published: August 2024

Alzheimer’s disease (AD) is the most common cause of dementia and one of the most prevalent neurodegenerative diseases. It begins with mild cognitive impairment and progressively affects all aspects of the patient’s life functions. Alzheimer’s disease is more commonly seen in the elderly and has a progressive incidence. With the global increase in the elderly population, Alzheimer’s disease poses a significant threat. Additionally, current medications do not prevent AD, highlighting the need for new drug molecules to be used in AD treatment. Although 1,3,4-thiadiazoles have many biological activities such as anticancer and antiviral, their activities on acetylcholinesterase (AChE) are also being investigated. For this purpose, three new 1,3,4-thiadiazole compounds were synthesized in this study. The structure determinations of these compounds were carried out using 1H-NMR and HRMS spectrophotometric methods. Activity studies were conducted in vitro using the modified Ellman method. As a result of the activity tests, compound 3b showed the closest effect to donepezil with an IC50= 0.096±0.004 µM.
Penguatan Strategi Penghimpunan ZIS di BAZNAS Kabupaten Sleman
Authors: Asmuni Asmuni
Published: August 2024

The increase in the amount of ZIS fundraising greatly impacted the welfare of the Ummah. For this reason, this community service activity aims to socialize the device strategy for implementing ZIS fundraising at BAZNAS, Sleman district, which has experienced an increase. Service activities are carried out using the method of socializing the zakat awareness movement directly to the community, opening consulting services online and offline, as well as conducting zakat role models which are expected to make people understand or be aware of the obligation to pay zakat. The results of community service activities include several strategies carried out by BAZNAS of Sleman Regency in raising ZIS funds, namely: 1) The strategy of awareness socialization of the zakat movement and related provisions can influence the muzaki's decision to pay zakat. 2) Opening an online zakat consulting service in the form of via WhatsApp and in-person consultation at the Sleman district BAZNAS office also has a significant impact on Muzaki. 3) Carry out the role model zakat movement every month, which also influences the muzaki's decision to pay zakat. It was concluded that the socialization of the Zakat awareness movement, consulting services related to Zakat, and the role model Zakat movement had a positive impact and succeeded in strengthening the ZIS fundraising process.
Memperkuat Keberlangsungan UMKM Melalui Pemasaran Berbasis Teknologi Di Desa Arul Kumer, Aceh Tengah
Authors: Maghfirani Maghfirani
Published: August 2024

The Unprecedented integration of technological has the potential to suport local and global economies and enterprise-level businesses to become more productive and sustainable. In simple terms, digitalization can be seen as increasing the generation, analysis and efficiency of data. The problem in Arul Kumer village is the low level of innovation and digitalization development. The Real Work Lecture (KKN) activity in Arul Kumer village which will be carried out in 2023 has the aim of providing training/assistance to the community in developing businesses, as well as strengthening business sustainability through digital technology, the use of social media as a promotional place and e-commerce as a market place , and assisting the community in maximizing the potential of the village's existing natural resources by carrying out innovation, and Digital Marketing strategies, the importance of business branding, procedures for photographing products and content that attracts consumers in order to win global competition and be able to reach a wider market automatically help improve the economy of the Arul Kumer village community.
Pemanfaatan Limbah Enceng Gondok Sebagai Kerajinan Tas
Authors: Purnomo Agus , Hani Umi , Purnamasari S , Zahra Maulida Atika , Hadi Abdul
Published: August 2024

Water hyacinth is a plant that grows in swamps and rivers. The presence of water hyacinth waste scattered across swamps and rivers makes rivers polluted. Having abundant and rotten water hyacinth waste can have an impact on health. There are empowerment activities for the community to utilize water hyacinth waste into handicrafts in the form of bags. The aim of community service is to utilize water hyacinth waste into craft materials that have sales value. The implementation of this service activity uses socialization methods and training on how to use water hyacinth waste to make handicrafts. Water hyacinth waste is cut into long shapes and then dried in the sun until dry. Results and discussion Water hyacinth waste leaves are taken and formed into the desired pattern. In forming the bag shape pattern, the size and shape of the leaves from the dried water hyacinth leaves will be arranged into handicrafts in the form of bags and other handicrafts.
Sosialisasi Upaya Peningkatan Pemahaman Digital Marketing Pada Desa Pasar Kecamatan Singkil Kabupaten Aceh Singkil
Authors: Fakhrurrazi Hardian
Published: August 2024

Current technological developments require the public, especially MSME business actors, to be able to use technology in the sales activity process. Technology has contributed greatly to the MSME sector. One of them is the use of social media as a means of digital marketing (digital marketing), Business actors in Pasar Village, Aceh Singkil District need to be given guidance regarding the application of digital marketing to their business. Providing digital marketing outreach for Pasar Village MSMEs to develop product marketing, Pasar Village MSMEs need the development of social media as a promotional tool. The aim of conducting this research is to provide an understanding of the importance of digital marketing for MSMEs in developing their businesses. The result of mentoring activities for the development of MSMEs by holding digital marketing outreach activities is that business actors have obtained social media accounts as a means of digital marketing as well as information on how to brand products
Peningkatan Kapasitas Manajemen Produksi dan Mutu Olahan Roti Tawar
Authors: Surbakti Dona Doni
Published: August 2024

The purpose of the Mandiri Real Work Lecture (KKN) for the community is to help the community by providing lessons on improving the quality of processed white bread. To educate the public on how to increase production capacity in processed white bread. And run all the KKN work programs that the author has made. The method of this research is observation, documentation, and interviews. The people of the clear Citaman village welcomed it, and they also said that with this training, they better understand and can easily use the technology that is currently available. At the preparation stage, students conduct a preliminary survey in Citaman Jernih Village to find out the condition of the target activity by analysing the conditions of the place to be used. Evaluation Stage Evaluation is carried out to measure the level of success of an activity that has been carried out in Citaman Jernih Village
Pelatihan Pembukuan Sederhana untuk Memonitor Perkembangan Usaha di Desa Pematang Guntung
Authors: Alni Jumiarti
Published: August 2024

The purpose of the Community Service Program activities through PKM (Community Partnership Program) in simple bookkeeping training to find out the business development of Pematang Guntung Village, Teluk Mengkudu District, Serdang Bedagai Regency is to be able to make their books so that they are orderly in carrying out financial records so that expenses, income and profits can be measured. obtained and can know the development of the USA. The method used is training. The results obtained from this training activity can increase entrepreneurial knowledge and skills in doing simple bookkeeping to increase motivation at work. The conclusion is that the simple bookkeeping training received a positive response, and business actors got simple bookkeeping/financial records that were easy to apply. The implication is that through simple bookkeeping training for shop businesses, rujak traders, and simple warungs, they can understand how to be a good entrepreneur through financial records.
CRIMINALIZAÇÃO DA HOMOTRANSFOBIA PELO STF: INTERPRETAÇÃO CONFORME OU ATIVISMO JUDICIAL?
Authors: Cardoso Fernando Cerqueira , Iribure Júnior Hamilton da Cunha
Published: August 2024

É como dizem, a diferença entre o remédio e o veneno é a dose. De fato, não há democracia constitucional estável e efetiva sem a intervenção jurisdicional. Porém, para que o modelo permaneça praticável, é indispensável que o protagonismo judicial seja substituído por atitude conscienciosa, atenta e sempre convencida do caráter objetivo e republicano de sua atuação. Não obstante a natural tentação de fazer prevalecer subjetividades e preferências axiológicas, cabe à magistratura, especialmente capitaneada pelo Supremo Tribunal Federal, conter-se ante os limites de ingerência prescritos pelo texto constitucional. Infelizmente, não foi o que ocorreu no julgamento da ação direta de inconstitucionalidade por omissão que criminalizou a homotransfobia (ADO 26/DF). Ante os limites e objetividade linguística, técnica e científica do texto, a Corte optou pelo malabarismo interpretativo. Longe de aplicar o princípio da interpretação conforme, como performaticamente anunciou, o que fez foi desconsiderar a cláusula de legalidade penal, fazendo prevalecer decisão manipulativa com efeito aditivo desamparada de hipótese constitucionalmente vinculada. Neste caso, o STF simplesmente fez o que quis, o que é ativismo judicial.
TUMOR BORDERLINE MUCINOSO DE OVÁRIO: UM RELATO DE CASO
Authors: Cerutti Maria Luiza de Castro , Côrtes Luciana Segurado , Ribeiro Nayra Nascimento , Caixeta Daniela Vieira , Lima Marina Saint'Clair Mattioda de , Albuquerque Júlia da Costa Barros Pedroso de , Silva Eduardo Resende Sousa e , Pes Isabel Cristina de Oliveira
Published: August 2024

Introdução: As neoplasias malignas do ovário estão inseridas em um grupo heterogêneo de doenças. Dentre os tumores ovarianos, são encontrados os carcinomas serosos, de células claras, endometrióide e os mucinosos. O tipo Borderline pode ser seroso ou mucinoso. O tumor borderline mucinoso de ovário é uma forma rara de apresentação e, geralmente está associada ao crescimento do tumor de forma rápida e exagerada, porém, em sua maioria, com desfechos favoráveis. Objetivo: Relato de caso clínico de um tumor borderline mucinoso de ovário em uma paciente jovem de 34 anos, sem comorbidades prévias, cujo diagnóstico e terapêutica instituídos resultaram em desfecho favorável. Métodos: Esse estudo do tipo relato de caso, descritivo apoiado por pesquisa quantitativa e para sua elaboração foram adotadas estratégias que se basearam em fundamentos teóricos provenientes de artigos científicos e literatura disponível a respeito de tumores ovarianos. Os instrumentos utilizados incluíram dados clínicos e sintomatológicos do paciente, obtidos por meio da revisão de prontuário e análise de exames complementares. Considerações finais: Embora raro, faz-se necessário o diagnóstico precoce do tumor Borderline mucinoso é imprescindível para um melhor prognóstico da paciente. Portanto, ter o conhecimento dessa condição, pode auxiliar a equipe médica na indicação de um tratamento e seguimento adequado.
POVO DE QUILOMBO NA CONSTITUIÇÃO BRASILEIRA DE 1988: UM RETROSPECTO DA LUTA POR JUSTIÇA SOCIAL NUMA ANÁLISE DISCURSIVA
Authors: Farias Enos André de , Barbosa Anna Christina Freire , Pacheco Clécia Simone Gonçalves Rosa
Published: August 2024

Este estudo tem como objetivo identificar os avanços decorrentes da inclusão do artigo 68 dos Atos das Disposições Constitucionais Transitórias (ADCT), que consagrou direitos fundamentais aos remanescentes de quilombos na Constituição Federal de 1988. Ele introduz o debate sobre a posse da terra, o respeito à identidade, cultura, subjetividade, memória ancestral e educação, elementos essenciais para a efetivação e proposição de direitos sociais. A pesquisa parte do problema da invisibilidade social e jurídica enfrentada pelos povos quilombolas brasileiros até então, ressaltando a necessidade de reconhecimento e proteção social. Destaca o discurso jurídico que, ao reconhecer os direitos dos povos quilombolas, reconfigura a relação desses grupos com a sociedade brasileira, promovendo sua autonomia e criando condições para a efetivação de direitos. Configura-se como exploratória-descritiva de natureza qualitativa e de cunho documental, norteada pela análise do discurso em Foucault (2014) para entender as relações de poder entre os sujeitos e suas práticas sociais diante da realidade dos sistemas disciplinares de controle. Como resultado pode-se aferir que a Constituição Federal de 1988 implementou avanços jurídicos na causa quilombola, quebrando paradigmas e criando marcos legais para a efetivação da justiça social, destacando a necessidade de um esforço contínuo para a superação das barreiras históricas de discriminação, negação, exclusão e apagamento histórico.
VIOLÊNCIA NO AMBIENTE DE TRABALHO: UM OLHAR SOBRE O SOFRIMENTO PSÍQUICO EM HOMOSSEXUAIS E LÉSBICAS
Authors: Araujo Andreia da Fonseca , Rossi Valquíria Aparecida , Paula Blanches de , Fernandes Maria do Carmo , Sousa Francisca Edinete Nogueira de , Ramos Silvania Rita , Frugoli Rosa
Published: August 2024

Este estudo integra a pesquisa O Sofrimento de Gays e Lésbicas Vítimas de Violência: Um Estudo do Fenômeno na Perspectiva da Psicologia Junguiana e objetiva compreender e analisar de que forma o fenômeno da violência no trabalho sobre homossexuais e lésbicas, impacta em suas vidas. Trata-se de pesquisa de caráter qualitativo, exploratória, desenvolvida por meio de estudo de caso, fundamentada nas contribuições da psicologia junguiana, dialogando com autores de orientações psicanalítica e fenomenológica que enfocam a sexualidade e as identidades de gênero como partes da dinâmica da personalidade, presentes em determinada época, cultura e socidade. Como resultado, evidencia-se que a homofobia e a lesbofobia estão presentes nas organizações de forma simbólica e moral, implícita e explicita, atuando em forma de violência manifesta de diversas formas, atuando como dispositivos de sofrimento psíquico e adoecimento de homossexuais e lésbicas. O estudo revela ainda a necessidade de se pensar em políticas públicas e práticas organizacionais que assegurem os direitos humanos, o respeito e a integridade de homossexuais e lésbicas.
OS IMPACTOS DAS POLÍTICAS DE AJUSTE ECONÔMICO NOS SERVIÇOS DE SAÚDE PARA A IMPLEMENTAÇÃO DO SISTEMA ÚNICO DE SAÚDE (SUS)
Authors: Fraga Silvana de Freitas Bomfim
Published: August 2024

A presente pesquisa visa trazer como as politicas de ajuste econômico afetam as a atividades inerentes a prestação de serviços públicos especialmente aqueles ligados a assistência à saúde, trazendo todo processo evolutivo de implantação das políticas públicas de saúde, assim como sua evolução desde do Brasil colônia, lutas e conquistas onde ocorreu a implementação do atual Sistema Único de Saúde (SUS) que vem sofrendo diferentes influências no decorrer de sua história. Hoje, o SUS opera em todos os municípios do país e, mesmo com suas muitas deficiências, representa um significativo avanço em relação ao cenário anterior à 1988 onde o acesso a saúde somente era ofertado a uma gama da população. Nesses mais de 30 anos da Constituição, o Sistema Único de Saúde consolidou-se como uma das mais importantes políticas sociais do Estado brasileiro, sob responsabilidade da União, dos estados e dos municípios. Falta, porém, evoluir o debate e construir um novo modelo de financiamento capaz de dar sustentabilidade ao sistema, de suportar as pressões de custos e evitar a obsolescência da rede de atendimento. Para elaboração da presente pesquisa foi utilizada a metodologia de revisão de literatura, através de uma pesquisa de natureza descritiva com uma abordagem qualitativa, com objetivo de: Analisar os impactos das políticas de ajuste econômico nos serviços de saúde para a implementação do sistema único de saúde (SUS). Sendo possível concluir que diversos são os desafios enfrentados pela gestão pública com relação a alocação dos recursos destinados as atividades mantidas pelo governo, para garantir que serviços como o SUS continuem sendo ofertados e o sistema não entre em colapso.
A IMPORTÂNCIA E VALORIZAÇÃO DO TRABALHO DOS AGENTES COMUNITÁRIOS DE SAÚDE NO MUNICÍPIO DE CRAÍBAS/ALAGOAS
Authors: Santos Maria Rayssa Gomes , Rocha Mabel Alencar do Nascimento
Published: August 2024

No panorama da saúde pública, a atenção primária se destaca como base fundamental para a promoção da saúde e prevenção de doenças, sendo o primeiro nível de contato dos indivíduos com o sistema de saúde. Este estudo investiga a importância e valorização dos Agentes Comunitários de Saúde (ACS) no município de Craíbas, Alagoas, explorando o impacto direto de suas atividades na saúde da população local e os desafios enfrentados em seu cotidiano. O objetivo é fornecer uma visão detalhada da relevância dos ACS na articulação entre a comunidade e os serviços de saúde. Para tanto, realizou-se uma análise bibliográfica abrangente e um levantamento quantitativo da quantidade de ACS em cada Unidade Básica de Saúde (UBS) do município. Além disso, aplicou-se um questionário aos ACS de Craíbas para coletar dados sobre perfil demográfico, condições de trabalho e experiência profissional. Os resultados indicaram a multifuncionalidade dos ACS e a necessidade de políticas públicas que valorizem esses profissionais. Destacou-se a importância da capacitação contínua e da melhoria das condições de trabalho para garantir uma atuação eficiente e segura. Conclui-se que a valorização e o fortalecimento dos ACS são essenciais para a promoção de uma saúde pública mais equitativa e eficiente. Este estudo contribui para a formulação de recomendações voltadas para o aprimoramento das políticas de saúde locais, visando o fortalecimento dos ACS como protagonistas na promoção da saúde e bem-estar da comunidade de Craíbas.
PENGARUH GAYA HIDUP TERHADAP PENGELOLAAN KEUANGAN MELALUI LITERASI KEUANGAN SEBAGAI VARIABEL INTERVENING PADA GENERASI Z DI KOTA PASURUAN
Authors: Evira Kusumaningtyas  , Yufenti Oktafiah  , Eva Mufidah
Published: August 2024

Pertumbuhan ekonomi yang semakin pesat dan diiringi kemajuan teknologi di era digital, oleh karena itu penting untuk memahami pengelolaan keuangan. Pemahaman pengelolaan keuangan bisa dijadikan bekal untuk mengatur keuangan. Berdasarkan hal tersebut maka peneliti ini bertujuan untuk menguji dan menganalisis pengaruh Gaya Hidup Terhadap Pengelolaan Keuangan Melalui Literasi Keuangan Sebagai Variabel Intervening Pada Generasi Z Di Kota Pasuruan. Populasi yang digunakan adalah Generasi Z di Kota Pasuruan dan sampel yang digunakan sebanyak 96 responden dengan teknik penarikan purposive sampling dalam pengambilan sampel. Analisis yang digunakan adalah uji instrument, analisis deskriptif, uji asumsi klasik, analisis jalur dan uji hipotesis. Hasil penelitian menunjukan bahwa 1) gaya hidup berpengaruh positif dan signifikan terhadap literasi keuangan dengan nilai koefisien positif sebesar 0,381 dan nilai sig 0,001. 2) Gaya hidup berpengaruh positif dan signifikan terhadap pengelolaan keuangan dengan nilai koefisien positif sebesar 0,110 dan nilai sig 0,023. 3) Literasi keuangan berpengaruh positif dan signifikan terhadap pengelolaan keuangan dengan nilai koefisien positif sebesar 0,500 dan nilai sig 0,000. 4) Gaya hidup (X) dan literasi keuangan (Z) secara bersama-sama (simultan) memiliki pengaruh signifikan terhadap variabel pengelolaan keuangan (Y) dengan pengaruh total sebesar 0,300 ,nilai ini > f tabel sebesar 2,70 dan nilai sig 0,001.
MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN TÌNH TRẠNG DINH DƯỠNG CỦA NGƯỜI BỆNH ĐÁI THÁO ĐƯỜNG TÝP 2 TẠI BỆNH VIỆN ĐA KHOA HUYỆN QUẢNG XƯƠNG THANH HÓA NĂM 2022
Authors: Hoàng Thị Trang , Phạm Thị Dung , Phạm Ngọc Khái , Phạm Thị Kiều Chinh
Published: August 2024

Mục tiêu: Xác định một số yếu tố liên quan đến tình trạng thừa cân-béo phì ở người bệnh đái tháo đường týp 2 điều trị ngoại trú tại bệnh viện Đa khoa huyện Quảng Xương, tỉnh Thanh Hoá năm 2022.
Phương pháp: Nghiên cứu cắt ngang được thực hiện trên 400 người bệnh mắc đái tháo đường týp 2 điều trị ngoại trú từ tháng 10 đến tháng 12 năm 2022. Đối tượng nghiên cứu được đo chiều cao và cân nặng, được phỏng vấn trực tiếp về thói quen ăn uống và lối sống. Các yếu tố liên quan đến tình trạng thừa cân-béo phì ở đối tượng nghiên cứu được xác định bằng mô hình hồi quy logistic. Kết quả được trình bày dưới dạng OR (95%CI).
Kết quả: Có 16% bị thừa cân-béo phì ở người bệnh đái tháo đường týp 2 ngoại trú. Các yếu tố liên quan đến tình trạng thừa cân-béo phì ở đối tượng nghiên cứu bao gồm thói quen ăn no (OR=3,98;95%CI=1,42-11,1), ăn không đúng giờ (OR=1,86; 95%CI=1,07-3,23), không có thói quen tập thể dục (OR=1,81; 95%CI=1,04-3,16), và thích ăn thịt rán (OR=2,09; 95%CI=1,03-3,24) so với những người không có đặc điểm trên.
Kết luận: Thừa cân-béo phì là vấn đề sức khoẻ ở người bệnh đái tháo đường týp 2. Do đó cần xây dựng các chương trình giáo dục sức khoẻ và can thiệp phù hợp nhằm phòng chống vấn đề sức khoẻ này.