bluuebunny/crossref_metadata_2025 huggingface dataset:
GLOBALIZATION AND REAL SECTOR PERFORMANCE IN NIGERIA
Authors: Nnamaka Uzoma Chidoka , Nnana Odungweru Kingsley
Published: November 2022

The need to provide a level playing field for national economies has necessitated the integration of the economies through cross flow of goods, services, technologies and capital. These goods and services are produced by key sectors of the economy which represents the real sector. Over the years, the competitiveness of the real sector in the international market has raised concerns on the link between globalization and real sector performance. Consequent upon this, this study examined the impact of globalization on real sector output in Nigeria for a 39 year time period spanning from 1981 to 2019. The time series datasets used in this study were adapted from the Central Bank of Nigeria’s Statistical bulletin. The Ordinary Least Squares and Error Correction Modeling were used as the main analytical tools. The Augmented Dickey Fuller unit root test showed that all the variables attained stationary after first difference. The Johansen cointegration test further showed that the series have long run equilibri um relationship at 5 percent level of significance. The result from the errorcorrection model confirms that about 38 percent of the short run shocks in real sector output is corrected annually. From the estimates, a positive and statistically significant relationship exists between real sector output and foreign direct investment. Trade openness also was significant in impacting real sector output positively while a negative and significant linkage was observed between exchange rate and real sector output in Nigeria. The study therefore concluded that openness to trade broadens real output growth. Based on the findings, the study recommends amongst others that in the quest to maximize the benefits from trade openness, the relevant authorities should ensure that the nation’s exports are competitive and meet international standards by leveraging on modern technol ogies and innovation. Also, favourable industrial policies and strong institutional framework should be set up by the government to attract the right foreign direct investments.
EMPIRICAL REVIEW OF IMPLICATIONS OF FINANCIAL LEVERAGE ON PERFORMANCE OF QUOTED OIL AND GAS COMPANIES IN NIGERIA
Authors: Etim Etim Osim , Ubi Peter Samuel , Etukafia Nseabasi Imoh , Enang Raymond Ekwere
Published: November 2022

This study was conducted to examine the implication of financial leverage on performance of quoted oil and gas companies in Nigeria. This is premeditated on the fact that debt capital is usually acquired by firm to finance assets with the expectation the returns from such investments will exceed the costs of the debt capital used. Often, this is always not the case either because of inappropriate management strategies or other reasons. Ex-post-facto research design was adopted involving use of panel secondary data as published by eight(8) oil and gas companies selected from the population of twelve(12) firms quoted on the floor of the Nigerian Stock Exchange (NSE) for the period 2006-2020. Descriptive and multiple linear regression statistics were used to analyze data collected. The dependent variable was return on Assets (ROA), proxy for financial performance and independent variables being financial leverage decomposed into Debt Ratio (DR), Debt-to-Equity Ratio (DER), Long-term Debt Ratio (LTDR) and Cost of Debt (COD,) Results Shows DR, LTDR and COD had negative and significant implications on ROA, while DER also had negative but insignificant implications on ROA of quoted oil and gas firms in Nigeria. Hence, it was concluded that during the period of the study, leverage had negative and significant implications on financial performance of oil and gas firm in Nigeria. It was recommended that oil and gas firm should minimize debt capital usage in their financial structure to shore-up returns.
EFFECT OF WORKING CAPITAL INVESTMENT AND FINANCING POLICIES ON THE PROFITABILITY OF LISTED INDUSTRIAL GOODS COMPANIES IN NIGERIA
Authors: Orban Msurshima Josephine , Abu Seini Odudu
Published: November 2022

Working capital and financing decisions or policies are essential in determining companies’ capacity to invest in any securities, be it non-current or current assets which has a significant role in retaining the organization’s liquidity, solvency, survival, continuity and profitability. This study investigates the effect of working capital investment and financing policies on the profitability of listed industrial goods companies in Nigeria. The ex-post facto research design was adopted, and data were sourced from annual reports and accounts of 21 listed industrial goods companies in Nigeria, out of which 14 firms were selected and form the sample size with 140 firm-year observations for the period of 10 years from 2012 to 2021. The ordinary Least Square (OLS) regression model was employed to analyze the data. The test of normality, multicollinearity, and heteroscedasticity were all conducted to improve the reliability and validity of statistical results. Also, the model selection using a Hausman specification test was conducted to determine between random and fixed effects models. The outcome enables the study to reject the fixed and accepted random effect estimator. The study established that aggressive and conservative investment policy have negative and insignificant impact on profitability. The conservative financing policy has a positive and insignificant effect on profitability, while aggressive financing policy has a positive and significant impact on profitability. Hence, the study concludes that aggressive financing policy and conservative financing policy improve profitability, and aggressive investment policy and conservative investment policy reduce the profitability of listed industrial goods companies in Nigeria. The study recommends that companies should mbrace aggressive financing policies as a way of increasing their profitability. This will enable the companies to use an appreciable level of current liability to finance their operations’ thereby attracting more improve to enhance a significant positive impact on their profitability. This will enable the companies to use more current assets to finance the industrial goods, thereby generating more profits for firms and shareholders.
OIL PRODUCTION AND THE NIGERIAN ECONOMY: AN ANALYSIS OF THE CONTRACTUAL ARRANGEMENTS
Authors: Otolorin Gabriel Efe , Nsudo Nsudoh Samuel , Ekong Christopher N , Essien Ettah Bassey
Published: November 2022

This paper is an assessment of the crude oil contractual arrangement in Nigeria. Following the ambiguity and secrecy surrounding the contractual arrangement in Nigeria as well as the call by researchers to shift away from joint venture agreement to production sharing contract, the study employed monthly time series data for the period 2017 – 2020 to search if there is a need to move away as well as possibility of seasonality in crude oil production by contractual arrangement and to determine the relationship between oil price, oil revenue and the contractual arrangement based on crude oil production. The empirical results clearly show a uni-causal relationship between exchange rate and JV as well as oil price and JV. The study also showed evidence of causality between PSC and exchange rate, as well as PSC and Oil Price. Which signifies changes in exchange rate and oil price granger causes changes in crude oil production by PSC and JV. The study also revealed that there is seasonality in production in the month of July and August which may have resulted to higher gross oil revenue noticeable in the third quarter. The study also discovers the likelihood for production and revenue to be lower in the first half of the year and higher in the second half of the year cumulatively. The study recommends that rather than shifting away from JV to PSC, the federal government should continue with all the contractual arrangement since they have their individual peculiarities but concerted effort should be made to encourage indigenous contract arrangement as already springboard through the marginal field. Also, the government should pay close attention going forward on the seasonal patterns as such information can be used for planning as there is the likelihood of FAAC to be higher or lower within the period identified in the study.
Challenges of Sugarcane Farmers in Sindh: A Micro-Level, Qualitative Study of Ghotki District
Authors: Mushtaq Ahmed , Khalil Ahmed Channa
Published: November 2022

Purpose: In Pakistan, sugarcane possesses significant importance in national agriculture to produce crystalline sugar and sugary production. However, the production is stagnant and faces multiple issues. This study aims to evaluate and solve the challenges that sugarcane farmers face in Sindh, providing evidence from sugarcane-rich district Ghotki.

Methodology: We collected the data from sugarcane farmers in four areas of the Ghotki district via five in-depth interviews and five focus group discussions.

Findings: The results pointed out that the sugarcane farmers are small landholders, and the sugarcane crop is their only source of livelihood. The significant challenges they faced were the sugarcane production system, land preparation, planting seasons, small landholdings, lack of capital, social problems, transportation, harvesting, and credit shortage.

Unique Contribution to Practice and Policy: These findings are crucial for responsible institutions, mainly agriculture extension in the province, to devise policies to improve their livelihoods. If the government takes necessary action on these challenges, production and yield can increase in-country and the national economy by exporting refined crystalline sugar.
Body Weight and Biometric Parameters of Piglets Reared under Intensive System of Management in the Humid Tropic
Authors: Odo B I , Obiagwu C C , Amalu T C
Published: November 2022

Purpose: A total of 60 pigs of both sexes (30 males and 30 females) reared under intensive system of management were randomly sampled and used in this study that lasted for 20 weeks, to assess the relationship between bodyweight and biometric parameters.

Methodology: Data obtained for bodyweight (kg), height (cm), body length (cm) and heart girth (cm) were subjected to Bivariate Pearson Correlation, analysed using SPSS version 25.

Findings: The result showed that despite higher numerical values recorded for female pigs, there were no correlation between sex and other body biometric parameters. However, body weight had strong correlation with other biometric parameters analysed. The body length had the highest direct contributions (r = 0.981) to body weight in male and female pigs respectively.

Unique contribution to theory, practice and policy: The forecast indices recorded in this work could be employed to predict bodyweight estimation and help in making management decision and breeding programs for genetic improvement in pigs.
An Analysis of Clustering the Decision Support Systems in Logistics for Supply Chain Management
Authors: Ghazali Ahmad Faiz , Suhaimi Aishah
Published: November 2022

Decision-making in logistics is becoming increasingly complex task for businesses such as agriculture, food production, and construction, as it requires decisions at the strategic, tactical, and operational levels, as well as consideration of the triple bottom line. Undoubtedly, decision support systems (DSS) played a crucial role in resolving the difficulties related with decision-making in sustainable logistics. The objective of this work is to investigate the status of research in the domain of DSS for logistics, taking sustainability into account. It is of the utmost importance to determine the prospective areas and significance of this research. By doing a bibliometric analysis, the purpose of this study is to illustrate the scientific research on the Decision Support System in Logistics. Using the Scopus database's VOSviewer programme and data analysis tool, the analysis was conducted. From 1985 to 2022, a total of 1091 papers on DSS and logistics connected to consumers were retrieved from the Scopus database. To show the progression of research ideas in this discipline, co-citation analysis and co-word analysis were undertaken. Transportation decision-making, decision analysis, and intelligence algorithm have been identified as the three primary study clusters relevant to the current research interest. This study's findings may assist researchers in comprehending the nature of Decision Support System research pertaining to logistics from around the world and in determining future research directions.
Kubernetes in Microservices
Authors: Nadaf Sarah R , Krishnappa H. K.
Published: November 2022

The move towards the microservice grounded armature is well underway. In this architectural style, small and approximately coupled modules are developed, stationed, and gauged singly to compose pall-native operations. still, for carrier- grade service providers to resettle to the microservices architectural style, vacuity remains a concern. Kubernetes is an open source platform that defines a set of structure blocks which inclusively give mechanisms for planting, maintaining, spanning, and healing containerized microservices. therefore, Kubernetes hides the complexity of microservice unity while managing their vacuity. In this paper, we probe further infrastructures and conduct further trials to estimate the vacuity that Kubernetes delivers for its managed microservices. We present different infrastructures for public and private shadows. We estimate the vacuity attainable through the mending capability of Kubernetes. We probe the impact of adding redundancy on the vacuity of microservice grounded operations. We conduct trials under the dereliction configuration of Kubernetes as well as under its most responsive bone . We also perform a relative evaluation with the Vacuity operation Framework( AMF), which is a proven result as a middleware service for managing high- vacuity. The results of our examinations show that in certain cases, the service outage for operations managed with Kubernetes is significantly high
Inventory Of Small-Scale Fishing Units In Tanjung Solok Village, Kuala Jambi District, Tanjung Jabung Timur Regency
Authors: Lisna Lisna , Saputra M. Ridho , Wiyanto Eko , H Afriani , Farhan Muhammad , Ramadan Fauzan
Published: November 2022

This study aims to identify and inventory the fishing units in Tanjung Solok Village, Kuala Jambi District, Tanjung Jabung Timur Regency. This research was conducted in June-July 2021. The method used in this study is a survey method, with direct observations in the field and conducting interviews with fishermen and noting the fishing units used by fishermen in Tanjung Solok Village. The sampling method is a census of 106 fishermen who have fishing units and domiciled in Tanjung Solok Village. The data collected in this study include general biographical data of fishermen, ships or boats used to catch fish, fishing gear used, and catches while fishing. The data analysis used in this research is Descriptive Data Analysis. Fishermen in Tanjung Solok are aged between 20 and 70 years with elementary, junior high and high school education and work as main fishermen, fishermen and side fishermen. The fishing vessels used are classified as outboard motor boats, non-motorized boats and motor boats made of fiber or wood with ship sizes of 1 to 4 GT. There are 7 types of fishing gear used, namely Gillnet, Mini Trawl, Pull Trawl, Splint, Rawai, Net, and Clam Stick and are dominated by fishing gear that is easy to operate and cheap. The most widely used fishing gear is the Gillnet. The fishing area for Tanjung Solok fishermen is around the territorial sea which is no more than 12 miles from the coastline because the fishing units are classified as small-scale. The fish caught by fishermen vary from shrimp and gulama fish, happy fish, side fish and shellfish.
Performance Of Vaname Shrimp (Litopenaeus Vannamei) Cultured On Green Water And Brown Water Biofloc Systems
Authors: Supono Supono , Cania Mega , Kurnia W Zevinna , Setyawan Agus , Sapto C.U Deny
Published: November 2022

Vannamei shrimp (Litopenaeus vannamei) is one of the mainstay commodities that can increase the country's foreign exchange because it has a fairly high selling value in the global market. Several problems in aquaculture can reduce vaname shrimp production such as disease, water quality degradation, and high feed conversion values. Biofloc is an alternative technology that can be applied to overcome the problems in shrimp farming. There are two types of biofloc technology, namely green water biofloc and brown water biofloc. This study aimed to study the effect of the application of the two biofloc systems on growth, survival rate, and feed conversion ratio of vaname shrimp. This study used a completely randomized design consisting of 3 treatments with 3 replications. The treatments were: (A) control, (B) green water biofloc, and (C) brown water biofloc. Shrimp rearing was carried out for 30 days, using a container with a volume of 70 liters of water. Each treatment unit was filled with 70 PL 10 fry, equivalent to 1 PL/liter. The results showed that the type of biofloc system affected the growth and feed conversion ratio of vaname shrimp, but had no effect on the survival rate of vaname shrimp. Green water biofloc produces better growth and feed conversion than brown water biofloc and control
Utilitization Of Catfish Bone Gelatin (Pangasius Sp.) In Marshmallow Products
Authors: Adi Catur Pramono , Prasetyati Sukma Budi , Sebayang Elvi Andriani Br , Aripudin Aripudin
Published: November 2022

To take advantage of the by-product of catfish bone, gelatin is made as a value added of the by-product of the fishery industry, because Gelatin using sapa bovine fish bone has the same characteristics as catfish bone gelatin. Gelatin is the main ingredient in the manufacture of marshmallows to improve texture and ebilite. The purpose of this study was to determine the panelists' preference for marshmallows with the addition of catfish bone gelatin into marshmallows and to conduct chemical quality tests (water content and ash content) on catfish bone gelatin marshmallows. The method used is descriptive method, the results of this study are marshmallow hedonic testing with the highest appearance parameter value found in the sample F2 = 7.54, namely the addition of 0.93 gram catfish bone gelatin. From the parameters of taste, aroma, and texture, the highest value was found in sample F3 with the addition of 1.16 gram catfish bone gelatin to get a taste parameter value of 7.72, an aroma parameter value of 7.52, and a texture parameter value of 7.66. In chemical testing, all samples met the standard of SNI 3547.2-2008 soft confectionery. In the water content parameter, the highest value was found in sample F2 of 11.85% with a maximum limit of SNI 3547.2-2008 soft confectionery 20.0%. In the ash content parameter, the highest value is found in the F2 sample of 0.455% with a maximum limit of 3.0%. In the protein parameter, the protein test was taken from the best sample of sensory test results, namely marshmallow with the addition of 1.17gram catfish gelatin and 2.34gram beef gelatin with a protein content test result of 0.315%
Quality Of Artificial Feed Using Koro Bean (Canavalia Ensiformis) As A Substitute Of Soybean Flour For Sand Lobster Feed (Panulirus Homarus)
Authors: Aryzegovina Reffi , Desmiati Ira , Aisyah Siti
Published: November 2022

One type of legume that is very suitable to be used as a raw material for making lobster feed is the sworded koro nut (Canavalia ensiformis). Soybeans which are a source of vegetable protein can now be supported by sword beans. The purpose of this study was to examine the quality of artificial feed using Koro Sword Nuts (Canavalia ensiformis) as a substitute for soybean flour for Sand Lobster (Panulirus homarus) feed. The method used is the experimental method with RAL using 4 treatments and 3 replications. The treatments in this study were A (artificial feed without sword koro beans (control)), B (2.5% sword koro beans in 1 kg artificial feed), C (3% sword koro beans in 1 kg artificial feed), and D ( 3.5% sword koro beans in 1 kg of artificial feed). Research data were analyzed using non-parametric Kruskal Wallis statistical test and described. The test animal used was the Sand Lobster (Panulirus homarus) with a size of 8-10 cm with an average weight of 200-300 grams. The results of the physical test showed that the parameters of breaking speed, level of hardness, level of homogeneity and attractiveness were significantly different from the use of Peanut Koro Sword flour, while the parameters of sinking speed and deliciousness were not significantly different. The results of the proximate chemical test of feed using the best swordfish flour was in feed B, which contained 9.34% Moisture Content, 11.87% Ash Content, Crude Protein (N x 6.25) 29.98%, Crude Fat 6, 84 %, Carbohydrates 41.92% and Crude Fiber 5.00 %.
Technical Study Of Anchovy Catch Effort With Purse Seine At Larangan Coastal Fishing Port, Tegal Regency
Authors: Kusnandar Kusnandar , Mulyani Sri , Wera Agung Ferdinand , Hs Dian Sutono
Published: November 2022

Larangan Coastal Fishing Port, located in Tegal Regency, Central Java, is one of the ports in Central Java with a fairly high fishery production. Purse seine Teri is one type of fishing gear used in PPP Larangan whose catch is fairly productive. The purpose of this research is to analyze the technical and financial aspects of capture fisheries business with purse seine Teri. The material used in this research is 8 units of purse seine Teri ship with lights. The method used is observation and interviews. Technical analysis includes the type of vessel, specifications fishing gear, and methods operation of fishing gear. Based on the technical analysis, the comparison of the dimensions of the vessel and the fishing gear is in accordance with the technical guidelines, namely the length of the fishing gear is at least 15 times the length of the vessel. The length of the bottom ris rope is an average of 13% of the top ris rope and accordance with the standart technical guidelines, which is a minimum of 10%. The average length of the corrugated rope is 1,3 from the length of the bottom ris rope, which is in accordance with the technical guidelines, which is between 1,1 - 1,75. The mesh size of the 0,5 inch is still safe because it is under the provisions of the technical guide, which is 0,6 inch
Performance Study Of 1.3 Ton Slurry Ice Machine Capacity In Cold Chain Fish Handling
Authors: Haris Dendi , Hs Dian Sutono
Published: November 2022

Slurry ice is a solution to improve the quality of fish caught and cultured. The purpose of this research is to analyze and test the performance of the slurry ice machine. The analysis used includes calculating the power performance coefficient (COP), refrigeration capacity (Q), refrigerant flow rate, volume flow rate, compressor work (WComp). The heat released by the condenser and the heat absorbed by the refrigerant in the evaporator. The calculation uses data from the measurement of condenser temperature, compressor pressure. Methods to calculate the calculation of specification data and pressure from the compressor use formulas. The results showed that COP = 3.8-4.3, Qtot = 9-10 kW (for each hour), m = 0.06 kg/s, Wcomp = 2.35-2, 6 kW, Qcond = 12, 4-12.52 kW, Qevap = 9.8-10.17 kW, the total refrigeration load for 24 hours is 228 kW. The total production of slurry ice for 24 hours is 1,396.8 kg or 1.3968 Tons. The results of the test on catfish that were cooled using slurry ice, the decrease in temperature from the initial temperature of catfish 27.8°C to a temperature of (-0.7°C) took 36 minutes. Meanwhile, chilled catfish using shaved ice with an initial temperature of 27.8°C catfish to 2°C takes 1 hour.
Analysis Of Antibiotic Residue On Vaname Shrimp (Litopenaeus Vannamei) In Kalipuro Intensive Pond, Banyuwangi
Authors: Andriyono Sapto , Kusumaningrum Faridha , Suciyono Suciyono
Published: November 2022

Antibiotics are compounds that are used to inhibit the growth of disease or are commonly referred to as drugs. Some examples of antibiotics most commonly used in shrimp culture are tetracycline, oxytetracycline, and chloramphenicol. In shrimp farming, antibiotics function as disease prevention or as a cure for the disease. But if the application is not under the dose, it will cause residues on the shrimp and harm human health if consumed. The purpose of this study was to determine the antibiotic content of tetracycline, oxytetracycline, and chloramphenicol in vannamei shrimp in intensive ponds in Kalipuro, Banyuwangi, East Java, and to determine the safety and feasibility of vannamei shrimp products consumed by the public based on the EDI (Estimated Daily Intake) and HQ (Hazzard) indexes. Quotients). The research was conducted using HPLC (High-Performance Liquid Chromatography) and ELISA (Enzyme-Linked Immunosorbent) methods to analyse the antibiotic content of vannamei shrimp then, the data obtained were processed using the EDI (Estimate Daily Intake) method to obtain daily estimates and HQ (Hazzard Quotient). to carry out an antibiotic risk assessment in the human body. The results obtained from this study were that vannamei shrimp in intensive ponds in Kalipuro, Banyuwangi, and East Java were negative for tetracycline, oxytetracycline, and chloramphenicol antibiotics. So the conclusion obtained from this study is that vannamei shrimp from intensive ponds in Kalipuro, Banyuwangi, and East Java is safe for consumption because it is negative for antibiotic residues.
Fish Losses of Euthynnus affinis Products at The Fish Landing Base Karangsong Indramayu, West Java
Authors: Sayuti Mohammad , Salampessy Randi Bokhy Syuliana , Ridzki Fajar
Published: November 2022

Euthynnus affinis is one of the most loved fish by the community. Fulfillment of the demand for tuna from the process of catching until it is landed for sale has the potential to experience a decrease in yield. The purpose of this study was to determine handling techniques, determine quality, and determine yield losses in tuna catches at the Karangsong Indramayu Fish Landing Base (PPI) West Java. The research was conducted by directly observing the handling process, observing the cold chain of tuna from unloading to loading, conducting organoleptic quality testing, ALT, TVB and calculating fish losses by referring to the Load Tracking (LT) method. The calculation of yield loss is carried out in three types, namely: physical loss, quality loss, and financial loss. The flow of the tuna handling process observed is the unloading process to the loading process. The value of the organoleptic quality test on tuna caught was 8, the ALT test value of the lowest average value was 16,000 col/g and the highest value was 35,000 col/g. The lowest average TVB test value was 9.96 mgN/100 g and the highest was 11.19 mgN/100 g. Euthynnus affinis from unloading to loading experienced physical, quality and financial losses of: 1.07%; 0.84%; and 2.05%.
Determinant Analysis Of Fresh Demand For Exported Tuna At Bungus Ocean Fishing Port (PPS) Padang City Postpandemic Covid-19 Period
Authors: Aisyah Siti , Aryzegovina Reffi , Rustam Dicky
Published: November 2022

The Covid-19 pandemic is claimed to be the main cause of the decline in world trade including trade in fishery products, where the total export value of world fishery products fell by 7% compared to 2019, which was the beginning of the Covid-19 pandemic. Therefore, the determinants of demand for fresh tuna exports at PPS Bungus, Padang City, in the post-pandemic Covid-19 period need to be investigated. to maintain and increase the quantity of fresh tuna exports. Based on the description above, the purpose of this study is to analyze the determinants of domestic price factors, Japan's Gross Domestic Product (GDP), shrimp prices, and the exchange rate on demand for fresh export tuna exports at the Bungus Ocean Fishery Port (PPPS). Padang city Post-pandemic Covid-19 period. To find out how much influence the independent variables and dependent variables have in this study, the method used is multiple regression analysis. The independent variables are tuna prices (X1), Japan's GDP per capita (X2), shrimp prices (X3), exchange rates (X4), and the dependent variable is the export quantity of fresh tuna (Y). Based on the results of the study, it was concluded that the price of tuna, shrimp price and exchange rate had a positive effect on the quantity of fresh tuna exports while Japan's GDP per capita had no effect on the quantity of fresh tuna exports at the Samudera Bungus Fishery Port, Padang City
Assessment of Youth Health in Uzbekistan According to the Results of Immunological Screening
Authors: O.I. Ergashov  , N.G. Gulyamov
Published: November 2022

An assessment of the health indicators of young people in Uzbekistan was carried out based on the results of immunological screening - determining the quantitative content of antigen-binding lymphocytes (ASL), sensitized to tissue antigens (TA) of various organs. For a comparative study, male and female volunteers aged 18-25 years old living in Tashkent city of the Tashkent region (northern region) and in the city of Termez of the Surkhandarya region (southern region) of Uzbekistan was examined. Consequently, in the southern region of Uzbekistan (Termez), the frequency of manifestation of pathological processes in various organs is relatively higher than in the northern region (Tashkent).
The Issue of Addressee and Addressee in Children's Quasidialogical Speech
Authors: Davlatova Ra’no Haydarovna
Published: November 2022

This article discusses the relationship between addresser and addressee in speech communication, the issue of addressee in quasi-dialogical speech, types of quasi-addressee and its manifestations in various speech situations.
Treatment of Chronic Heart Failure with a Low Ejection Fraction with Sacubitril/Valsartan (Uperio) on the Background of Diabetes Mellitus
Authors: I.K. Abdullaev  , R.B. Fayzullayev  , J.I. Reymberganov
Published: November 2022

This article analyzes the process of treating patients with CHF and CHF with a low ejection fraction against the background of type 2 diabetes mellitus. Approximately 1-2% of the adult population of developed countries have heart failure (HF), in patients over the age of 70, the risk of developing HF is more than 10%. In 2016, a new drug appeared in the arsenal of cardiologists — sacubitril/valsartan (Uperio), which is a complex of a non-lysine inhibitor and an angiotensin-2 receptor blocker. The study was randomized - 27 reviewers hospitalized for the period February – March 2022: 21 / (78%) men, and 6 / (22%) women. By week 10, 17 / (63%) patients received the target dose of the drug - Uperio, by week 18 – 20 / (74%) (Table No. 2). In two patients, the titration of the dose of the drug - Uperio was not carried out due to the development of symptomatic arterial hypotension. Nine patients by week 20 received a dose of 100 mg 2 times a day of the drug - Uperio. 5 of them had a decrease in eGFR. Patients showed improvements in the clinical picture, an increase in the functional class according to NYHA, improvements in laboratory data (decrease in creatinine levels, decrease in NT-proBNP levels), as well as positive dynamics on EchoCG.
Comparative Standardization Study of Ayurvedic Formulations of Gokshuradi Churna
Authors: C. Kavitha  , C.N. Nalini  , R. Radha  , T. Purushoth Prabhu  , R. Vijaya Bharathi
Published: November 2022

Background: The knowledge of plant based medicines was gradually developed by the primeval persons and was passed on to generations by trial and error basis without proper scientific evaluation, safety and toxicological studies. The discovery and acceptance of natural therapies in the past decades has been increasing in both developing and developed countries. Consumers buy herbal products without a prescription through online. Thus standardization is required with systematic approach and well-designed methodologies to maintain uniformity between batches during production of herbal products. The present work aims for the comparative standardization of the marketed formulation and two in-house prepared Gokshuradi Churna. It is an ayurvedic formulation prescribed for inflammation, arthritis, and other joint disorders. Gokshuradi Churna consists of powdered mixture of herbal drugs in equal proportions: the fruits of Tribulus terrestris, the fruits of Terminalia chebula, the root of Boerhaavia diffusa, the wood of Cedrus deodara, the rhizome of Zingiber officinale, and the bulb of Allium sativum. Materials and Methods: The churna was standardized on the basis of the parameters like organoleptic characters, physical characters, physicochemical properties, phytochemical screening. Results: The parameters studied were within standard limits and the quality of the products were established. The results obtained may be considered as reference standards for developing standard formulation. Conclusion: From preliminary studies, it confirms that In house and marketed formulations of Gokshuradi Churna is safe for therapeutic use. Further studies has to be done to confirm the pharmacological activities of the churna.
Postoperative Ovarian Reservation Salpingectomy with Ovarian Preservation during Hysterectomy based on AMH Measurement Before and After Surgery: A Systematic Review and M
Authors: Effat Al-Sadat Sharifzadeh  , Parvin Mostafa Gharabaghi  , Fariba Pashazadeh  , Mahdi Zarei  , Mohadeseh Aqayinejad
Published: November 2022

Introduction: To the best of our knowledge, there is no strong evidence for the effect of salpingectomy on the surgical outcome of a standard hysterectomy. Therefore, we decided to conduct a study entitled ovarian reservation after salpingectomy with ovarian preservation during hysterectomy based on AMH measurements before and after surgery as a review until 2019.Materials and Methods: In addition to the 503 studies found in the initial database search, two more studies identified through a reference list of related articles and a Google Scholar search were added. After removing duplicates, the titles and abstracts of the remaining 475 studies were reviewed and 30 studies were selected to review the full text. Then seven studies were deleted and finally 12 studies were reviewed and 11 of them were meta-analyzed.Results: AMH levels before and after salpingectomy were compared with patients in 12 studies. Compared with AMH before salpingectomy, AMH levels after salpingectomy were significantly lower (SMD = -0.35); 95% confidence interval (CI95%): -0.55 - -0.15 (p = 0.001). The results of studies on differences in AMH levels before and after salpingectomy did not show a statistically significant diffusion bias (Egger's P-value = 0.304).Conclusion: The present study showed that the level of AMH hormone was significantly reduced after salpingectomy. One of the limitations of the present study was the lack of surgical complications, the amount of intraoperative bleeding and the duration of surgery in most studies.
Investigating the Return Possibility of Covid-19 Mutated Strains and Role of Vaccination in Present and Future
Authors: Kambiz Sadegi  , Dadkhoda Soofi  , Hosein Mirshekarpour  , Hosien Pormasoumi
Published: November 2022

Covid-19 has killed more than 7 million people in the world so far. With general vaccination in 2021, the severity of deaths decreased significantly, but after 6 months, new types of Covid-19 emerged and deaths incidence increased. Epidemiological studies showed that despite high number of deaths, vaccination has reduced the severity of the disease in population. Many researchers did not suggest injecting third and fourth doses due to antigenic changes of virus, but some countries, such as Iran, have continued vaccination. In America and European countries, it has been suggested that vaccination should continue only for high-risk people. Biological science has not rejected dangerous mutations for this virus and has prepared itself to face mutated species of this virus again. Certainly, vaccination is the most important way to deal with the virus in future; but despite millions of mutations in Covid-19 virus structure, the compatibility of vaccine with new viral antigens is important in order to provide effective vaccines with high efficiency.
The Impact of the Development of Digital Information Technologies on the Labor Market
Authors: Rakhmanbaeva Roza Abdurakhmanovna
Published: November 2022

This article presents data on the state of the process of digitalization of the economy and concludes about the high level of development of information infrastructure, at the same time, there is a strong gap in the level of digitalization between regions. When assessing the impact of the development of Internet technologies on employment, two main consequences are identified: a decrease in the impact of the geographical factor on supply and demand in the labor market and the involvement of previously unoccupied social groups in the production process. The results of these consequences are divided into opportunities and threats for the population, and their analysis is carried out separately for the population of the periphery.
Development of Technology for Obtaining Dry Extract "LEFOSED"
Authors: M.T. Matazimov  , Z.E. Sidametova  , N.K. Olimov
Published: November 2022

For the first time, a technology for obtaining a dry extract of "Lefosed" with sedative activity and meeting the requirements of GF XI from a 4-component collection has been developed. The extraction method was chosen, as well as optimal conditions allowing depleting the raw materials as much as possible and enriching the extract with a complex of biologically active compounds contained in the feedstock. The technological characteristics of the dry extract have been studied and determined, with the aim of its further use as a raw material for the production of finished dosage forms.
Dynamics of Anthropometric Indicators in Women of Fertile Age with Cushing's Syndrome After Surgical and Drug Treatment
Authors: Z.Y. Xalimova  , O.B. Irgashev  , S.S. Issaeva  , Xolova D. Sh  , N.A. Yuldasheva
Published: November 2022

We studied the dynamics of anthropometric indicators in 153 women of fertile age with Cushing's syndrome, who applied for excess weight, lack of menstruation and infertility in the RSSPMC of Endocrinology of the PHM of the Republic of Uzbekistan, from 2000 to the present. The control group consisted of 20 women with obesity of varying degrees and without menstrual irregularities.According to the classification of the American Association of Endocrinologists from 2012, all female patients with SC registered since 2000 (the dead are not included) were distributed according to etiology as follows: 1 g. - patients with ACTH-dependent CS– 115 (75.2%), 2 g. - with ACTH-independent CS - 35 (22.9%) and group 3 - patients with ACTH-ectopic CS - 3 (1.9%). 6 months after surgical and drug treatment, in groups 1 and 2 of patients there was a significant improvement compared with the average OT, OB, OT / OB data before treatment, while in patients of 3 groups there were significant changes in the average OT, OB, OT values / OB after 6 months of treatment not established.
TRACES OF THE ORIGIN OF TRADITIONAL SPORTS IN ÇILDIR BAŞKÖY ROCK ART
Authors: Yavuz GÜNAŞDI  , Uğur KARCIOĞLU
Published: November 2022

Archaeological documents are the most important source for the periods when there were no written documents. Rock art drawn by human beings are one of these sources. Through these pictures, information about the social, economic, cultural and even sports activities of the period can be obtained. Çıldır district, Damlıca village and Başköy stream, which were determined by our team in the light of the surveys, are valuable in this respect in the depictions in the rock art. In our study, information about the origin of traditional sports is given in the light of Başköy rock art. Suggestions regarding the origin of the javelin and taigan race were made in the light of the depictions on the panel on which the rock art were processed. Our research, in the light of archaeological data, reveals that the origins of traditional sports, which are still played today, are quite old.
EXAMINATION OF THE RELATIONSHIP BETWEEN EMOTION REGULATION AND DECISION-MAKING SKILLS OF ORIENTEERING ATHLETES
Authors: Abdulsamed Akyüz  , Aydın Karaçam  , Aygül Çağlayan Tunç  , Ali Selman Özdemir
Published: November 2022

The aim of the study is to examine the relationship between emotion regulation skills and decision-making skills of orienteering athletes together with some demographic characteristics. This research is descriptive research in relational screening model. The sample of the study consisted of orienteering athletes over the age of 18 who were active in 2021-2022 in Istanbul. The sample of the research consists of 300 active orienteering athletes selected by convenience sampling method. Of these athletes, 82% (n: 246) are male and 18% (n: 18) are female. The "Rational and Intuitive Decision-Making Styles" scale developed by İme et al. (2020) was used to measure the decision-making skills of orienteering athletes, and the Athlete Emotion Regulation Scale developed by Tingaz and Altun (2021) was used to measure the emotion regulation skills of orienteering athletes. SPSS 25.0 program was used in the analysis of the data. In the analysis of the data, descriptive statistics, pairwise comparisons t test and Pearson Correlation test were used. When the change of the athlete emotion regulation scale according to gender is examined; female athlete emotion regulation level is significantly higher than males. When the rational and intuitive decision-making styles scale according to gender is examined, it has been observed that the total of the scale differs significantly in favour of male according to gender. The total rational and intuitive decision-making scale was positively correlated with the overall athlete emotion regulation scale at the level of .327, with the suppression sub-dimension at the level of .302, and with cognitive reappraisal at the level of .241. It was found that the rational sub-dimension was positively correlated with the athlete's emotion regulation scale at the level of .242, positively at the level of .181 with the suppression sub-dimension, and positively at the level of .234 with the cognitive reappraisal. It was found that the intuitive sub-dimension had a positive correlation at the level of .256 with the athlete's emotion regulation scale, a positive correlation at the level of .266 with the suppression sub-dimension, and a positive correlation at the level of .149 with the cognitive reappraisal.
Microneedle: Recent Advancements In Transdermal Drug Delivery System
Authors: Bhavya patel  , Foram parekh  , Krupa vyas  , Pragnesh patani
Published: November 2022

Due to its reduced invasiveness, low rejection rate, and remarkable ease of administration, transdermal drug delivery (TDD) has recently become a viable alternative to oral and injectable administration. The transdermal medication delivery method is a treatment strategy that is extraordinarily safe and well-tolerated and has enormous potential for delivering active ingredients against a variety of illnesses. However, because to the low skin permeability of the majority of active medicines in the formulation, its application is currently restricted in clinical settings. To get over this restriction, new strategies for skin permeation improvement techniques are offered. The drug delivery industry has undergone a revolution due to recent advances at the nano and microscale. A growing trend in drug delivery applications is the use of several kinds of microneedles (MNs), in particular because they are safe, compliant with patient preferences, and practical. Microneedles are a distinct, cutting-edge, and successful method created to administer medicinal chemicals and immunological components in a number of disorders. With appropriate examples and recent developments, various MN types—solid, hollow, coated, dissolving, and hydrogel forming—are described. We summarize recent developments in microneedles for therapeutic uses in this review.
Effects of Caffeine on Human Body
Authors: Dhruv S Patel  , Yashica Rawal  , Pragnesh Patani
Published: November 2022

Throughout the beyond a decade, Food Rule Experts have deduced that caffeine usage isn't risky at whatever point consumed at levels of 200 mg at a time (around 2½ cups of coffee) or 400 mg everyday (around 5 cups of coffee). Moreover, caffeine has various positive exercises on the frontal cortex. It can augment availability and success, help obsession, further foster perspective likewise, limit distress. Caffeine could disturb rest, regardless, simply in fragile individuals. It could raise anxiety in a little subset of particularly fragile people. Caffeine does not seem to provoke dependence, yet a minority of people experience withdrawal secondary effects. Caffeine can potentiate the effect of standard torment alleviating drugs in cerebral agony and migraine. Well established coffee/caffeine usage has been connected with expectation of mental disintegration, and diminished risk of making stroke, Parkinson's ailment and Alzheimer's ailment. Its usage does not seem to influence seizure occasion. Thusly, everyday coffee and caffeine confirmation can be significant for a strong changed diet; its use does not ought to be ended in elderly people.
Diabetic Wound Healing with Nanofibers
Authors: Prachi Patel  , Yashica Rawal  , Pragnesh Patani
Published: November 2022

The most prevalent metabolic illness, diabetic mellitus (DM), is caused by a problem with insulin production. DM promotes the gradual degeneration of pancreatic cells, which raises blood sugar levels. Around 2.1 trillion dollars are invested in global health industries by diabetic wound repair therapies. This is a result of the difficulties that skin ulcers offer in the wound healing process, such as a shortage of macrophage and fibroblast growth factors (TGF-b1 and PDGF, respectively), all of which are required for the production of extracellular matrix (ECM). Nanofibers have been created by electrospinning with large porosity, excellent humidity absorption, a superior oxygen exchange rate, and certain antibacterial properties in response to the growth of medicinal materials and pharmaceutical technology. By including bioactive substances (such growth factors, genes, proteins/peptides, stem cells/exosomes, etc.) and nonbioactive materials, these nanoparticles/hydrogels aid in the healing of diabetic wounds (metal ions, oxygen, nitric oxide, etc.) Due to the slow wound healing process, wound care is a significant biomedical topic that presents difficulties. Malnutrition, insufficient oxygen, smoking, illnesses (such as diabetes and cancer), microbial infections, and other conditions are some of the causes of sluggish wound healing. Currently utilized wound dressings have a number of drawbacks, such as inadequate antibacterial action. Thus, we aimed to go into further depth about the NF (nanofiber) system's aforementioned characteristics for DM complications.