bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Na2CO3 on production of NaHCO3 using desulfurized Na2SO4 waste
Authors: Lim Chaehyun , Byun Youngchul , Kim Hwan Ki , Park Sang Sook , Min Jung Gi
Published: December 2023

CO2 is the primary greenhouse gas emitted through human activities which cause global warming. Many countries and international regulations aim to reduce CO2 and encourage development of a net-zero society by 2050, thus, CCUS (carbon capture, utilization, and storage) can be considered as a key technology for achieving this goal. Among the many industrial processes, NaHCO3 production is a representative CCUS technology which satisfies both CO2 reduction and economic incentive. Recently, Na2SO4 waste, containing 15% impurities (i.e., various heavy metals), produced as a by-product generated from desulfurized processes in steel industry has received a great deal of attention since landfilling has been the only way to treat it. Na2SO4 could be a suitable source of NaHCO3 production as CCUS; however, there are no commercial processes for production of NaHCO3 using Na2SO4 as the raw material, since it has low production efficiency compared to other Na+ sources. This study evaluates the regeneration of NaHCO3 using Na2SO4 waste and our results show that a combination of Na2SO4 waste and the addition of 20% Na2CO3 can sharply increase the yield of NaHCO3 while minimizing the consumption of expensive NH3.
Major depletion of insulin sensitivity-associated taxa in the gut microbiome of persons living with HIV controlled by antiretroviral drugs
Authors: Belda Eugeni , Capeau Jacqueline , Zucker Jean-Daniel , Chatelier Emmanuelle Le , Pons Nicolas , Oñate Florian Plaza , Quinquis Benoit , Alili Rohia , Fellahi Soraya , Katlama Christine , Clément Karine , Fève Bruno , Goujard Cécile , Lambotte Olivier , Doré Joël , Prifti Edi , Bastard Jean-Philippe
Published: December 2023

Background. Persons living with HIV (PWH) harbor an altered gut microbiome (higher abundance of Prevotella and lower abundance of Bacillota and Ruminococcus lineages) compared to non-infected individuals. Some of these alterations are linked to sexual preference and others to the HIV infection. The relationship between these lineages and metabolic alterations, often present in aging PWH, has been poorly investigated. In this study, we compared fecal metagenomes of 25 antiretroviral-treatment (ART)-controlled PWH to three independent control groups of 25 non-infected matched individuals by means of univariate analyses and machine learning methods. Moreover, we used two external datasets to validate predictive models of PWH classification. Next, we searched for associations between clinical and biological metabolic parameters with taxonomic and functional microbiome profiles. Finally, we compare the gut microbiome in 7 PWH after a 17-week ART switch to raltegravir/maraviroc.
Results. Three major enterotypes (Prevotella, Bacteroides and Ruminococcaceae) were present in all groups. The first Prevotella enterotype was enriched in PWH, with several of characteristic lineages associated with poor metabolic profiles (low HDL and adiponectin, high insulin resistance (HOMA-IR)). Conversely butyrate-producing lineages were markedly depleted in PWH independently of sexual preference and were associated with a better metabolic profile (higher HDL and adiponectin and lower HOMA-IR). Accordingly, butyrate production and amino-acid degradation modules were associated with high HDL and adiponectin and low HOMA-IR. Random Forest models trained to classify PWH vs. control on taxonomic abundances displayed high generalization performance on two external holdout datasets (ROC AUC of 80-82%). Finally, no significant alterations in microbiome composition were observed after switching to raltegravir/maraviroc.
Conclusion. High resolution metagenomic analyses revealed major differences in the gut microbiome of ART-controlled PWH when compared with three independent matched cohorts of controls. The observed marked insulin resistance could result both from enrichment in Prevotella lineages, and from the depletion in species producing butyrate and involved into amino-acid degradation, which depletion is linked with the HIV infection.
The loss of sperm storage ability in females as a potential driver for increase extinction in Chondrichthyes
Authors: Lamarca¹² Felipe , Carvalho³ Pedro Hollanda , Ferreira André Luiz Netto
Published: December 2023

Sperm storage in females (SS) has been reported in Chondrichthyans species, and involves the prolonged maintenance of viable sperm after mating events, prior to egg fertilization. Along with multiple paternity (MP – female producing Offspring of multiple males within the same litter), SS has been hypothesized to be related to the increased reproductive fitness of cartilaginous fish lineages. The present study aims to investigate if: (1) are SS and MP evolutionarily related and share the same evolutionary history in Chondrichthyes? (2) How the presence of SS is implied in the extinction and speciation rates and thus related to the current species diversity of the group? To answer these questions, we obtained SS and MP records for Chondrichthyes species from the literature and performed ancestral reconstruction analyses for each character in the phylogenetic. We employed MEDUSA and MiSSE to detect if shifts in diversification rates were related to characters along the phylogeny. Finally, we utilized HiSSE to calculate the net diversity rates for observed and unobserved states. The ancestral reconstruction indicates that both characters are plesiomorphic for the group, SS is suggested to be absent in Lamniformes and Rhinopristiformes, whereas MP may be absent in Galeocerdo cuvier. MEDUSA and MiSSE detected that all clades lacking SS showed no increase in rates, whileareas higher diversification rates in clades with SS. HiSSE identified lower net diversity rates in clades with lacking SS associated with hidden states. Therefore, SS seem to contribute to increase extinction rates by reducing diversity among the Chondricthyes.
Comparison of Air Quality in Kathmandu, Nepal before and during COVID-19 Lockdown
Authors: Maharjan Bishwash , Joshi Yadav Prasad , Pokhrel Amod Kumar , Marahatta Sujan Babu
Published: December 2023

A lockdown strategy was adopted to control COVID-19 transmission in Nepal. We investigated the possible impacts of lockdown on air pollution ( PM2.5, and O3 ) levels and trends before and during the COVID-19 lockdown period in Kathmandu Valley. Secondary data from seven air quality monitoring stations in Kathmandu Valley was obtained from starting of 2018 to mid-June of 2020. The nonparametric linear regression slope (Theil-Sen slope) and Mann Kendall test for significant trends over time were applied to assess the air pollution levels and trends. Both PM2.5 and O3 levels showed cyclic and seasonal variations. PM2.5 peaked in winter, while the O3 level had a significant peak in the spring and summer seasons. PM2.5 and O3 concentrations decreased significantly during the lockdown period compared to the same period of the previous years by 31.66% and 8.17%, respectively. Theil-Sen slope estimates showed a statistically significant declining monthly average level of PM2.5 μg m-3 (-9.55; 95CI: -15.87; -5.26; p <0.001) and O3 μg m-3 (-1.68; 95CI: -3.22; -0.01; p <0.01), respectively. The decline in air pollution levels is likely due to the lockdown, including travel restrictions and industrial shutdowns. While the lockdown policy seems to curb air pollution, there is an economic burden associated with it. The government should consider policies such as introducing electric vehicles, vehicle restriction, and congestion charges, encouraging electricity-based cooking and increasing investment in bicycle lanes and public transportation to curb air pollution in Kathmandu Valley.
3D residual attention hierarchical fusion for real-time detection of the prostate capsula
Authors: Wu Shixiao , Guo Chengcheng , Litifu Ayixiamu , Wang Zhiwei
Published: December 2023

Background: For electrosurgery of the prostate, which relies on surveillance screens for real-time operations, manual remains the primary method for prostate capsula identification, rapid and accurate detection becomes urgency.We aimed to develop a deep learning method for detecting prostate capsula using endoscopic optical images.
Methods: Firstly, the SimAM residual attention fusion module is used to enhance the feature extraction ability of texture and detail informations. Secondly, the enhanced details information at the lower level is transferred to the higher level in a hierarchical manner to facilitate the extraction of semantic information. Finally, based on SimAM residual attention and forward hierarchical feature-by-feature fusion, an improved single-shot multibox detector model based on 3D unparametric attention fusion is proposed.
Results: A forward feature-by-feature hierarchical fusion network based on the 3D residual attention mechanism is proposed for the fast detection of the prostate capsula. The proposed network can better extract the regional features of the image, the extracted network features retain the spatial structure of the image, and realize the rapid detection of medical images.
Conclusions: The speed of the proposed model can reach 0.014ms on NVIDIA RTX 2060, which realizes the rapid detection. The model AFFSSD composed of unparametric attention fusion and progressive fusion of forward features can achieve 83.12% detection precision. Compared with Faster R-CNN (ZF, VGG16, ResNet 50), SSD(VGG16, ResNet 101), EfficientDet (D0-D7), FoveaBox, TOOD, YOLOv4, Sparse R-CNN, OWOD, .R-FCN(ResNet-50), FSSD(VGG16), the proposed method AFFSSD had the highest mAP and faster speed, only lower than YOLOv7.
Transcriptomic analysis of powdery mildew resistance in contrasting wheat genotypes
Authors: Khaliliazar Reza , Golparvar Ahmadreza , Zahravi Mehdi , Bihamta Mohammadreza , Javanmard Hamid Reza
Published: December 2023

Powdery mildew (Blumeria graminis f.sp. tritici) is one of the important diseases of wheat that economically decrease wheat production annually. Meanwhile, resistance mechanisms of resistant genotypes in wheat are not yet entirely clear. Therefore, in the present study, two contrasting genotypes of bread wheat (Triticum aestivum L.), Bolani as a sensitive and TN72 as a resistant genotype, were subjected to the fungi to finding differential expressed genes (DEGs) through RNA sequencing technique. According to the results of transcriptome analyses, a total of 2827 and 3105 DEGs were identified in the sensitive (1507 up- and 1320 down-regulated) and resistant (1484 up- and 1621 down-regulated) genotypes, respectively. Functional annotation of stress responsive genes using MapMan detected key pathways including cell wall, fatty acid, redox, amino acid biosynthesis and light reaction pathway. These results suggest that resistant genotype hires efficient mechanisms to deal with the Bgt, and can be used for further investigations.
Biodegradation of Phenanthrene by Alcaligenes ammonioxydans, (VITRPS2) strain isolated from petroleum contaminated soil: Degradation, Inhibition kinetics and metabolic pathway
Authors: K Sumathi , Manian Rameshpathy
Published: December 2023

The compound, Phenanthrene, a three-ring polyaromatic hydrocarbon (PAH) commonly occurs in the environment and it is derived from grilled meals, tobacco, crude oil, coal tar and automobile exhaust among other sources. Phenanthrene has been identified as a potentially hazardous PAH. Bioremediation is the most popular way of elimination technique since it is a sustainable solution that results in full mineralization of Phenanthrene. In this study, we aim to perform the biodegradation of phenanthrene by using the strain, Alcaligenes ammonioxydans (VITRPS2) which is isolated from petroleum-contaminated soil. At 5 mg/ml, the degradation rate constant was found to be 0.0181/day with half-life values of 2.7 as per first-order kinetics and 4.49 as per second-order kinetics. We employed one factor at a time (OFAT) approach to optimize the biodegradation conditions of the strain within the framework of Luria‐Bertani (LB) media. The isolate exhibited the ability to achieve maximum growth of 5mg/ml of phenanthrene as the exclusive carbon source under optimal conditions. These conditions included a pH level of 8.0, an inoculum concentration of 8%, along with a temperature of 37°C throughout 7 days of incubation period. The strain exhibited a degradation efficiency of up to 72% for phenanthrene, given optimal environmental conditions. The gas chromatography-mass spectrometry (GC-MS) analysis of the breakdown products unveiled the existence of the principal metabolites of the pathway, such as salicylic acid, catechol & various phthalic acid derivatives. The strain demonstrates that there are considerable potential applications in the remediation of an environment polluted by polycyclic aromatic hydrocarbon (PAH) metabolites.
Design and Analysis of Ultra-Wideband Microstrip Patch Antenna for Different Conductive Materials for Terahertz Gap
Authors: Singh Kritika , Dhayal Marshal , Dwivedi Smrity
Published: December 2023

The paper explores the design and analysis of a wideband microstrip patch antenna with a metallic patch and a 3x3 split ring resonator (SRR) array operating in the 0.1-5 THz frequency range. The antenna's structure incorporates different conductive materials such as gold, silver, and graphene as a metallic patch. The dimensions of the metallic patch and SRR are calculated to achieve wideband operation within the desired THz range. The SRR array enhances electromagnetic resonance, thereby improving bandwidth and radiation characteristics for medical imaging. The study discusses the equivalent circuit and design equations for the microstrip patch antenna and SRR unit cell. For designing and analysing the proposed antenna, CST Microwave Studio 2019 software have been used. Performance parameters such as return loss, bandwidth, gain, efficiency, directivity, VSWR, and radiation pattern have been evaluated. The advantages and limitations of each conductive material are evaluated to determine their suitability for THz-based medical imaging applications. The goal is to maximize the antenna's bandwidth, gain, and image resolution for medical imaging purposes. The findings highlight the performance characteristics of gold, silver, and graphene as conductive materials for medical imaging applications, facilitating the development of high-resolution, non-invasive imaging systems with improved diagnostic capabilities.
Omega-3 fatty acids prevent gestational diabetes mellitus via modulating lipid metabolism
Authors: Zhang Xuan , Li Fang , Yang Botao , Zhang Wei
Published: December 2023

Background
The incidence rate of gestational diabetes mellitus (GDM) is still high among pregnant women in the second trimester of pregnancy. This study explored the therapeutic effects of omega-3 fatty acids (ω-3 FAs) on GDM at the cellular and animal levels.
Methods
THP1 cells were stimulated with phorbol 12-myristate 13-acetate (PMA) to induce M0 macrophage. The transformation of M0 macrophages into M2 macrophages was observed after ω-3 FAs treatment. Then, macrophages induced by ω-3 FAs were co-cultured with hepatocytes HepG2, and the glycolipid metabolism in hepatocytes was assessed. By establishing a GDM mouse model, the impact of ω-3 FAs on liver function in GDM pregnant mice and offspring was evaluated.
Results
At the cellular level, we found that ω-3 FAs can promote the transformation of M0 macrophages into anti-inflammatory M2 macrophages, and the transformed M2 macrophages can prevent excessive accumulation of lipid droplet in hepatocyte cell line HepG2, by promoting β-oxidation and reducing lipid synthesis of hepatocyte, thereby protecting hepatic function. Supplementation of ω-3 FAs in pregnant GDM mice significantly reduced fasting blood glucose levels, GTT and ITT indexes, and lipid accumulation in the liver, and effectively prevented liver fibrosis. ω-3 FAs also had positive effects on the offspring of GDM pregnant mice, demonstrated by reducing birth mortality and improving glycemic stabilization.
Conclusion
This study suggests that ω-3 FAs prevent GDM via modulating lipid metabolism and may provide a strategy for translational medicine that can treat GDM and offspring.
Are Systemic Inflammation Response Index and Systemic Immune-Inflammation Index an ideal biomarker for epileptic patients?
Authors: Sönmezler Abdurrahman , Şanlı Zeynep Selcan , Boz Pınar Bengi , Keşkek Şakir Özgür
Published: December 2023

Background and Purpose
inflammation is considered responsible for the pathogenesis of epilepsy. Inflammation plays a pivotal role in epilepsy.Various inflammatory markers are known related to epilepsy. No study has yet investigated the relationship between epilepsy and systemic inflammation response index (SIRI) and systemic immune-inflammation index (SII). This study aimed to evaluate the systemic inflammation response index (SIRI) and systemic immune-inflammation index (SII) in epilepsy.
Methods
This study included patients with epilepsy who presented to the neurology department within last five years.
Results
The epileptic group included 110 patients (63 males, 47 females) and the control group included 65 healthy individuals (33 males, 32 females). The mean age of the epilepsy (n = 110) and healthy control group (n = 65) was 33.0 ± 14.0 and 34.0 ± 10.2 years, respectively. SII and SIRI levels were 603.0 ± 469,6 and 1,42 ± 1,08 in the epileptic group and 567.6 ± 218.9 and 1,16 ± 0,58 in the control group. There were no significant differences between two groups (p > 0.05).
Conclusion
Our study results suggest that although is an associated with inflammation, SII and SIRI are still not an ideal biomarker for epileptic patients. This study is important because it investigated SII and SIRI in patients with epilepsy for the first time. Further prospective studies involving a larger sample size should be performed to have more valuable results for interpretation.
Developing Predictive Model for Court Decision Using Machine Learning Approach
Authors: Arera(MSc) Lecturer Milkesa Dejene , Worku(MSc) Lechisa Kelbessa
Published: December 2023

There are a number of areas in which AI could have a significant impact on the legal system. This study attempts to develop predictive model for court decision of Jimma Zone High Court by using machine learning approach. The proposed predictive model was trained on a dataset which includes every major criminal cases happened from 2010–2014 E.C. in Jimma Zone. A regression predictive model was constructed by using various machine learning algorithms to predict court decision. Among the various machine learning algorithms applied for the predictive model are Linear Regression, Huber Regression, Random Sample Consensus Regression or RANSAC, TheilSen regression, and Extreme Gradient Boosting. These algorithmswere evaluated on the dataset by using k-fold cross-validation testing procedure, where k = 5. Accordingly, the proposed machine learning models showed different results on the given dataset by using MAE evaluation metric reveals that Extreme Gradient Boosting regression algorithm appears to be the best-performing, scores MAE of about 4.080. On the other hand, TheilSen performed the worst, MAE of about 17.146. Linear, Huber, and RANSAC have also shown they do not have skill on the given dataset. They score MAE of about 14.899, 13.195, and 16.020, respectively. Then, Extreme Gradient Boosting was used as a final model and made predictions on sample rows of data. Finally, the model was deployed using Gradio GUI library which helps to create user interfaces and share with a link to colleagues or stakeholders. As a future work, investigation needs to consider tuning hyper parameters, and calculating optimized values for these parameters has to be considered.
Otel İşletmelerinde Kurumsal Sosyal Sorumluluk ve İşe Adanmışlık: Afyonkarahisar Örneği (Corporate Social Responsibility and Work Engagement in Hotel Businesses: Afyonkarahisar Case)
Authors: KART Nurullah , PELİT Elbeyi
Published: December 2023

Günümüzde yaşanan teknolojik devrimler neticesinde, birçok iş kolunda teknoloji insan kaynağının yerini almaya başlamıştır. Fakat emek yoğun bir sektör olarak nitelendirilen turizm sektöründe insan kaynağı önemini korumaya devam etmektedir. Bu sebeple çalışanların işe adanmışlık düzeylerini etkileyin faktörlerin tespit edilmesi önemli bir husus haline gelmiştir. Bu çalışmada, çalışanların kurumsal sosyal sorumluluk algısının işe adanmışlık düzeyleri üzerindeki etkisinin belirlenmesi amaçlanmıştır. Araştırmanın evrenini UNESCO Gastronomi Şehri Afyonkarahisar'da bulunan beş yıldızlı otel işletmelerinin yiyecek-içecek departmanı çalışanları oluşturmaktadır. Verilerin analizi sonucunda elde edilen bulgulara göre çalışanların kurumsal sosyal sorumluluk algılarının ve işe adanmışlıklarının orta düzeyde olduğu belirlenmiştir. Bununla birlikte çalışanların kurumsal sosyal sorumluluk algısı ile işe adanmışlık düzeyleri arasında anlamlı bir ilişki olduğu ve kurumsal sosyal sorumluluk algısının işe adanmışlık düzeyini anlamlı şekilde etkilediği tespit edilmiştir. Çalışanların kurumsal sosyal sorumluluk algısının işe adanmışlık düzeyleri üzerindeki etkisini belirlemeyi amaçlayan bu çalışma, ilgili literatüre katkı sağlaması açısından önemlidir. Ayrıca çalışanların işe adanmışlık düzeylerini arttırmak için kurumsal sosyal sorumluluk faaliyetlerinden faydalanabileceğini göstermesi sebebiyle turizm sektörüne fayda sağlaması beklenmektedir.
Elektronik Ağızdan Ağıza Pazarlama Bağlamında Müşteri Değerlendirmeleri ile Gastronomi İmajı Arasındaki İlişki: Gaziantep Üzerine Bir Araştırma (The Relationship Between Customer Evaluations and Gastronomy Image in the Context of Electronic Word of Mouth Marketing: A Research on Gaziantep)
Authors: DÜZGÜN Mehmet
Published: December 2023

Gastronomi turizmi bağlamında faaliyet gösteren yiyecek içecek işletmelerine yönelik turist beklentileri sürekli artmaktadır. Bu durum rekabetin her geçen gün daha da hızlanması sonucunu meydana getirmektedir. Yapılan bu araştırma Unesco Yaratıcı Şehirler Ağı gastronomi kategorisnde yer alan Gaziantep’te gerçekleştirilmiştir. Elektronik ağızdan ağıza pazarlama ürün veya hizmete yönelik kullanıcılar ve alıcılar arasında meydana gelen bir iletişim biçimidir. Bu doğrultuda araştırmanın temel amacı Gaziantepte’te faaliyet gösteren turizm işletme belgeli yiyecek içecek işletmelerini ziyaret turistlerin elektronik ağızdan ağıza pazarlama çerçevesinde yapmış oldukları değerlendirmeler ile gastronomi imajı arasındaki ilişkinin ortaya konulması olarak ifade edilebilir. Nitel desende tasarlanmış olan bu araştırmada verilerin toplanmasında doküman incelemesi yöntemi kullanılmış ulaşılan veriler içerik analizine tabi tutulmuştur. Araştırma kapsamında işletmelere yönelik değerlendirmeler fiyat ve menü, hizmet ve servis, fiziki yapı ile yiyecek ve içecekler temaları altında gruplandırılmıştır. Ulaşılan sonuçlara göre turistler fiyatların yüksek olduğunu ve menülerin içerik anlamında yetersiz olduğunu değerlendirmişlerdir. Ayrıca sunulan yiyecek ve içeceklerin ağırlıklı olarak lezzetli olarak nitelendirildiği ve işletmelerin mekansal anlamda ergonomik olarak ifade edildiği belirlenmiştir.
Evaluation of Foreign Visitors Turkish Cuisine Experiences on Tripadvisor, an Online Platform: The Case of İstanbul-Beyoğlu
Authors: RAMADANOĞLU Elif , İNCE KARAÇEPER Ecem
Published: December 2023

The present study aimed to evaluate the Turkish cuisine experiences of foreign visitors through Tripadvisor, an online platform. In line with this purpose, 82 different food establishments with the concept of "Historical Turkish Restaurants, Esnaf Restaurants (restaurants where many dishes from Turkish cuisine are served and the customer prefers one of the options), and Kebap/Pide/Ocakbasi Restaurants (kebab restaurants that serve their customers at tables around a grill)" in the Beyoğlu district of Istanbul Province and included in the Tripadvisor website were analyzed. The content analysis technique, one of the qualitative study methods, was employed in the study. The ranking was from the restaurants that received the most visitor reviews between 2021 and 2022 to the restaurants that received the fewest reviews in order to obtain the total number of reviews on the Tripadvisor website. Especially post-pandemic comments were analyzed to ensure that the data were up-to-date and evaluable. The research data is limited to positive foreign visitor comments in the most common seven different foreign languages between 2021 and 2022. The research resulted in a total of 3455 positive reviews of Turkish cuisine restaurants in the last year (2021-2022). In order of importance, these positive comments are grouped under the categories of taste, service, price, menu, quality, location, and hospitality. These also revealed that foreign visitors focused most on the "taste and service" categories. The absence of any other study examining the Istanbul-Beyoğlu region in previous online evaluation studies emphasizes the importance of this study. This study is thought to shed light on the studies to be conducted in the future, especially on Turkish cuisine.
The Fallout of the Pandemic: An Investigation of Oman Tourist Destination Brand Equity
Authors: JAIN Vishal , JAIN Parul
Published: December 2023

Oman is in the process of diversifying its economy by identifying other sectors to lessen dependency on petroleum products. Many such sectors are identified as tourism, manufacturing, fisheries, mining, transportation, and logistics. Coronavirus pandemic has a significant impact on the global economy. As countries around the globe begin to emerge from the pandemic, what will be the new normal for tourism? This new normal is already beginning to affect tourism sector in Sultanate of Oman. The present study explores how the fallout of the pandemic will affect destination brand equity from a tourist perspective. However, most of the previous studies that deal with the similar issues, do not include effective ways to develop Oman tourism destination as a brand. The results reveal that destination Oman significantly satisfies all dimensions of brand equity, i.e., brand awareness, perceived quality, brand association, and brand loyalty. The perceived risk dimension is also extracted in the study to recognize the impact of pandemic crises.
İzmir in Coğrafi İşaretli Lezzeti: Boyoz Yeme Motivasyonunun Tekrar Ziyaret Etme Niyeti Üzerine Etkisi (Geographically Indicated Product of Izmir: The Effect of Boyoz Eating Motivation on Revisit Intention)
Authors: CAN GABERLİ Yağmur , GABERLİ Ümit , GENÇ Volkan
Published: December 2023

Bu çalışmada, İzmir’in coğrafi işaretli ürünü Boyoz yeme motivasyonunun tekrar ziyaret etme niyetine etkisi ölçülmüştür. Bunun için, İzmir'i ziyaret edip, en az bir kez Boyoz tadımı yapmış turistlerle online ve yüz yüze anketler yapılmıştır. Heyecan, kültür, duyusal ve sağlık faktörlerinin kısa, orta ve uzun vadede yeniden ziyaret etme niyetine etkileri incelenmiştir. Yapılan 453 anket sonucunda; heyecan faktörünün kısa, orta ve uzun vadede, kültürel ve sağlık faktörlerinin ise sadece orta ve uzun vadede yeniden ziyaret etme niyetine etkisi olduğu tespit edilmiştir. Bu açıdan İzmir’de Boyoz tadımı, turistlerin gezilerini daha renkli ve çekici hale getirme potansiyeline sahiptir. Bu çalışma, Boyoz ile ilgili atölye çalışmalarını, yerel ürünün hikâyesinin anlatılmasını kullanılan farklı sunum tekniklerini Boyoz’a olan ilgiyi arttıracak faaliyetler olarak önermektedir. Ayrıca, bu interaktif çalışmaların sosyal medya ve benzeri mecralarda paylaşılması ile Boyoz’un duyusal çekiciliğinin ve turistlerin heyecan motivasyonunun arttırılabileceği sonucuna ulaşılmıştır.
Cuestiones de autoridades administrativas de consumo en un país federal
Authors: Del Huerto Aquino Silvina Analía , Tambussi Carlos Eduardo
Published: December 2023

La consagración constitucional y legislativa de los derechos de usuarios y consumidoresmotivó que los Estados crearan las agencias con competencia en la materia a los fines de fiscalizarel cumplimiento de las normas. En los países federales, surgió el tema de las competenciasde los organismos nacionales en relación con las atribuciones de los estados integrantes de lafederación. A este aspecto se ha dado una respuesta legislativa que en la práctica no resulta deltodo clara. El propósito de este trabajo es el de reflexionar sobre la jerarquía administrativa de lasautoridades de consumo, a la par que indagar sobre las llamadas “facultades concurrentes” entrelas esferas federal y local, y la necesidad que el precepto legal se conjuge, en la práctica, con elprincipio de coordinación administrativa, a los fines de un actuar eficaz de los poderes públicos.
Intoxicación accidental con Fosfuro de Aluminio
Authors: Rodríguez Velarde Giancarlo Jesús
Published: December 2023

Paciente varón de 14 años, residente del Bajo Piura, ingresó a la emergencia el 14-04-23 connáuseas, vómitos y dificultad respiratoria, falleció poco después de ingresar a emergencia. Senotificó a la policía, y a Medicina Legal, en la escena secundaria, se encontró un cadáver con laspupilas midriáticas, con corneas transparentes, livideces dorsales sin signos de putrefacción, rigideztotal con temperatura corporal fría. Con tiempo de muerte de 10-12 horas. En la necropsia, seencontró un edema cerebral, contenido espumoso blanquecino y edema de la mucosa en víasaéreas superiores e inferiores con líquido espumoso en los pulmones, con hepatomegalia con unpatrón moteado plomizo. El diagnóstico fue asfixia por obstrucción de vías aéreas con edemaagudo de pulmón y edema multiorgánico. En la escena primaria donde sucedieron los hechos, seencontraron frascos que contenían fosfuro de aluminio, lo que se correlaciona con lo encontradopost mortem.
Adana İlinde Bir Tekstil İşletmesindeki Avrupa Birliği Yeşil Mutabakatı Uygulamalarının Çok Kriterli Karar Verme Yöntemleriyle Analizi
Authors: KOÇ Duygu Durdu , ABDULVAHİTOĞLU Aslı , ABDULVAHİTOĞLU Adnan
Published: December 2023

Küresel düzeyde, ülkelerin sürdürülebilir kalkınma hedeflerine ulaşma çabalarında enerji önemli bir rol oynamaktadır. Özellikle enerji üretim sektörüne yapılan yatırımların, sürdürülebilir enerji politikalarının geliştirilmesine katkısı, ülkelerin uluslararası konumları açısından belirleyici bir ölçüt olarak kabul edilmektedir. Bu çerçevede, ülkelerin yerel ve yenilenebilir enerji kaynaklarını en üst düzeyde kullanma amacıyla gerçekleştirecekleri yatırımlar, ekonomik büyüme, kesintisiz enerji temini, çevre duyarlılığı ve verimlilik kriterlerini etkileme zorunluluğunu içermektedir. Mevcut üretim tesislerinde ise artan enerji maliyetleri, katılaşan emisyon standartları ve sürdürülebilir üretim ilkesinin yaygınlaşması firmaları bazı tedbirler almaya zorlamaktadır. Bu bağlamda birçok sektörde olduğu gibi tekstil sektörü de, temiz üretim ve enerji verimliliği uygulamalarına yönelmektedir. Bu yaklaşım sayesinde, kaynağında bütüncül bir strateji ile enerji tüketimi azaltılarak, hem enerji kaynaklarının korunması hem de yeşil hedeflerin gerçekleştirilmesine katkı sağlanması amaçlanmaktadır. Mevcut literatürde, tekstil sektöründe enerji verimliliği ve temiz üretim konularında sınırlı sayıda ölçekli çalışma bulunmaktadır. Bu çalışmada, Adana Organize Sanayi Bölgesinde Faaliyet gösteren entegre bir tekstil tesisi örneği üzerinde uygulanan en uygun enerji verimliliği projeleri ile enerji kaynaklarından doğalgaz tüketiminin azaltılmasını hedeflemektedir. Bu şekilde, incelenen tekstil tesisinin sürdürülebilir tekstil üretimi ve temiz üretim hedeflerine katkı sağlaması beklenmektedir. Gerçek boyutlarda gerçekleştirilen bu enerji verimliliği çalışmasında, çok kriterli karar verme süreçlerini kullanılarak yürütülen projelerin ağırlıkları veya önem dereceleri belirlenerek, önem derecesi yüksek hedeflere öncelik verilmesi önerilmiştir. Böylece optimum verimliliğin sağlanmasına yönelik bir yol haritası sunularak, sektörün sürdürülebilir vizyonunu güçlendirmeye potansiyel sağlanması hedeflenmiştir.
Winkler Tipi Elastik Zemine Oturan Fonksiyonel Derecelenmiş Malzemeli Kirişlerin Statik Analizi
Authors: ASLAN Timuçin Alp , NOORI Ahmad Reshad , SİVRİ Burkay , TEMEL Beytullah
Published: December 2023

Bu çalışmada, Winkler tipi elastik zemine oturan ve kalınlık boyunca fonksiyonel derecelenmiş (FD) malzemeli kirişlerin eğilme davranışı üzerine bir inceleme yapılmıştır. Farklı mesnet koşullarının, malzeme değişim katsayılarının ve Winkler zemin katsayısının FD kirişlerin statik davranışı üzerine etkileri parametrik olarak incelenmiştir. Ele alınan problemin davranışını idare eden denklemler Euler-Bernoulli kiriş teorisine (EBKT) dayanan minimum toplam potansiyel enerji ilkesinin yardımıyla ilk defa bu çalışmada elde edilmiştir. Elde edilen bu kanonik denklem takımının sayısal çözümünde Tamamlayıcı Fonksiyonlar Yöntemi (TFY) ile Runge-Kutta 5 (RK5) algoritması kullanılmıştır. Önerilen yöntemin doğruluğu ve uygulanabilirliği, literatürde verilen mevcut çalışmaların değerleri ile bu yöntemin sonuçlarının karşılaştırılmasıyla gösterilmiştir. Malzeme değişim katsayısı, Winkler zemin katsayısı ve sınır koşulları ele alınan probleme önemli ölçüde etki etmektedir.
Cilt Kanseri Tanısında Tıbbi Görüntüleri Kıldan Temizlemek İçin Kullanılan İki Yeni Filtre
Authors: YILMAZ Berceste , TANDİROVİÇ GÜRSEL Amira
Published: December 2023

Geleneksel dermoskopik cihazların pahalı olması nedeniyle ulaşılabilirliğinin düşük olması ve uzman hekimlerin mesleki deneyimlerinin yeterli olmayışı cilt kanserinin erken teşhisinde en engelleyici faktörlerdir. Ancak bu alanda daha önce yapılan çalışmalar, çekim sırasında daha az uzmanlık gerektirdiğinden daha ekonomik ve pratik olan dijital benzerlerinden ziyade ağırlıklı olarak yüksek kaliteli dermoskopik görüntülere odaklanmıştır. Bununla birlikte, gürültünün yüksek varlığı nedeniyle tanıda bunların kullanımı zordur ve bu da zahmetli bir filtreleme işlemine neden olur. Filtrelemeyle ilgili en büyük zorluklardan biri, renk, şekil ve kalınlıktaki büyük farklılıklar nedeniyle kılın temizlenmesidir. Kıl temizliği, teşhisin kendisini sabote edebileceğinden teşhis için çok önemli olan verilerin sıkı bir şekilde korunmasını dikkate alan kapsamlı bir yaklaşım gerektirir. Makalede bu amaç için tasarlanan iki yeni filtrenin ana hatları verilmekte ve bu alanda yaygın olarak kullanılan iki filtreye göre performansları incelenmektedir.
A língua afiada de Aurélia à luz de Bakhtin: que carnaval é esse?
Authors: Souza-Silva André Luiz , Lima Thainá da Costa , Francelino Pedro Farias
Published: December 2023

O presente artigo analisa, a partir da cosmovisão bakhtiniana de carnavalização, a obra Aurélia – a dicionária da língua afiada (2013), uma vez que essa produção inverte ideais de uma obra oficial em um instrumento permeado por uma linguagem oriunda da cultura popular. Esse material metalinguístico é apontado como um dicionário que apresenta 1.300 verbetes típicos das práticas de linguagem de membros da comunidade LGBTQIAP+, obviamente com ressalvas, haja vista sua produção não advir do rigor da lexicografia tradicional, mas o que não deixa de representar uma visão de mundo de sujeitos de linguagem, os quais integram a referida comunidade. Dito isso, este artigo corresponde a uma análise interpretativista de viés dialógico-discursivo, considerando uma leitura dos elementos linguísticos e não-linguísticos que permeiam o material: verbetes, notas introdutórias, capas, figuras etc., caracterizando-se, assim, como uma pesquisa de natureza qualitativa de caráter documental. Nessa direção, lançamos mão das discussões do Círculo de Bakhtin, especialmente as ideias sobre carnavalização, com vistas à espetacularização da referida obra, a comicidade dos signos linguísticos e a “quebra” da seriedade do gênero verbete. Tais aspectos confirmam a irreverência de Aurélia e sua identidade itinerante no seio de uma sociedade que preconiza a cultura da norma gramatical e da ortografia oficial para fins de padronização (socio)linguística.
CONHECIMENTO MATERNO SOBRE OS CUIDADOS BUCAIS DAS CRIANÇAS NA PRIMEIRA INFÂNCIA
Authors: Morais Thalita Sonaly da Costa , Pessoa Daniela Mendes da Veiga
Published: December 2023

Introdução: Os pais exercem um importante papel no estabelecimento dos hábitos saudáveis durante a infância. Ao prestarem cuidados bucais necessários às suas crianças, observa-se um significativo resultado na prevenção dos agravos. Objetivo: Identificar o conhecimento materno sobre os cuidados bucais das crianças na primeira infância. Metodologia: Trata-se de um estudo de natureza quantitativa do tipo exploratório e observacional. A coleta ocorreu através da aplicação de um questionário semiestruturado, com questões sobre o conhecimento materno em relação à higiene bucal, hábitos alimentares, acometimento de cárie e perfil socioeconômico. Realizou-se uma análise descritiva dos dados, seguida de análise bivariada pelo teste do Qui-quadrado de Pearson, considerando-se um nível de significância de 5%. Resultados: Sobre o conhecimento dos cuidados bucais dos filhos, o mesmo encontrou-se insatisfatório em relação à idade em que as crianças devem começar a escovar seus dentes sozinhas, quanto ao uso de escova e do creme dental fluoretado como método de higiene após a erupção do primeiro dente e quanto à inexistência do dente decíduo antes do nascimento dos molares permanentes. Observou-se conhecimento satisfatório em relação à importância de se realizar restauração em dente decíduo acometido por cárie, à idade em que a criança troca os dentes decíduos pelos permanentes e, à realização de algum cuidado bucal (fralda e gaze) antes do nascimento do primeiro dente. Conclusões: Há uma lacuna quanto às orientações de saúde bucal providas pelos dentistas direcionadas às mães. As mães/gestantes têm o conhecimento adequado sobre os cuidados bucais do bebê, porém, quanto aos cuidados após o nascimento do primeiro dente, os resultados foram desfavoráveis. Faz-se necessário a maior participação do cirurgião-dentista nas consultas de pré-natal e de crescimento e desenvolvimento praticando educação em saúde.
Palavras-Chave: Saúde bucal; Cuidado infantil; Percepção; Higiene Bucal; Padrões de Cuidado Materno.
Three-Dimensional Mixed Convection in a Cubical Cavity with Nanofluid
Authors: Saliha Bellout , Rachid Bessaïh
Published: December 2023

The present study reports numerical simulations of three-dimensional

laminar mixed convection heat transfer of water-based-Al2O3  nanofluid in an open 

cubic cavity with a heated block. Ansys-Fluent 14.5 was used to simulate 3D flows

with heat transfer. Streamlines, isotherms, vertical velocity profile, and local Nusselt

numbers are presented for Reynolds numbers in the range (300<Re<700), volume

fractions of nanoparticles (0<ϕ<0.08) and heat source location (1cm <d <3cm). It was

found that when adding nanoparticles to the base fluid or increasing the volume

fraction of nanoparticles, the Nusselt number increases. Moreover, the heat transfer rate

increases when the Reynolds number increases.
Macular Perfusional Findings in Venous Obstructive Disease and Its Treatment: An OCT-A Evaluation
Authors: Yasin M. Naveed , Taiyab Aftab , Quiroz-Reyes Miguel A.
Published: December 2023

The human retina is supplied by an extensive network of capillaries, where healthy blood flow to various parts of the retina, particularly the macula, is vital for visual functions. Any obstruction in blood flow, known as retinal vein occlusion (RVO), can reduce venous blood return. RVO can occur either at a central location (called central retinal vein occlusion [CRVO]) or a peripheral location (branch vein occlusion [BRVO]). Various techniques have been used to investigate blood flow to the retina and analyze different factors that may impact retinal blood flow. Optical coherence tomographic angiography (OCT-A) has emerged as one of the best methods, with several studies demonstrating its use to investigate changes in blood perfusion status, hemorrhage from blood vessels, and the presence of edema. Some studies have demonstrated that OCT-A is superior to other techniques.
Macular edema secondary to RVO is the most common complication that may affect visual acuity and lead to vision loss if left untreated. Several qualitative and quantitative changes caused by RVO can be detected using OCT-A, including vascular blood perfusion and vascular density. Several treatment options have been used to treat macular edema secondary to RVO and other complications. Laser photocoagulation therapy has been used extensively in the past with mixed outcomes. Glucocorticoids, especially dexamethasone (Ozurdex®), have also been used to treat macular edema secondary to RVO. Currently, anti-vascular endothelial growth factor (VEGF) agents are the gold standard for treating RVO. Ranibizumab and aflibercept are approved for the treatment of macular edema secondary to RVO, with faricimab expected to soon be approved.
COVID-19 Vaccination Reactions and Risk of Breakthrough Infections Among People With Diabetes: Cohort Study Derived From Community Reporters
Authors: Dreyer Nancy A , Knuth Kendall B , Xie Yiqiong , Reynolds Matthew W , Mack Christina D
Published: December 2023

Background

This exploratory study compares self-reported COVID-19 vaccine side effects and breakthrough infections in people who described themselves as having diabetes with those who did not identify as having diabetes.

Objective

The study uses person-reported data to evaluate differences in the perception of COVID-19 vaccine side effects between adults with diabetes and those who did not report having diabetes.

Methods

This is a retrospective cohort study conducted using data provided online by adults aged 18 years and older residing in the United States. The participants who voluntarily self-enrolled between March 19, 2021, and July 16, 2022, in the IQVIA COVID-19 Active Research Experience project reported clinical and demographic information, COVID-19 vaccination, whether they had experienced any side effects, test-confirmed infections, and consented to linkage with prescription claims. No distinction was made for this study to differentiate prediabetes or type 1 and type 2 diabetes nor to verify reports of positive COVID-19 tests. Person-reported medication use was validated using pharmacy claims and a subset of the linked data was used for a sensitivity analysis of medication effects. Multivariate logistic regression was used to estimate the adjusted odds ratios of vaccine side effects or breakthrough infections by diabetic status, adjusting for age, gender, education, race, ethnicity (Hispanic or Latino), BMI, smoker, receipt of an influenza vaccine, vaccine manufacturer, and all medical conditions. Evaluations of diabetes medication-specific vaccine side effects are illustrated graphically to support the examination of the magnitude of side effect differences for various medications and combinations of medications used to manage diabetes.

Results

People with diabetes (n=724) reported experiencing fewer side effects within 2 weeks of vaccination for COVID-19 than those without diabetes (n=6417; mean 2.7, SD 2.0 vs mean 3.1, SD 2.0). The adjusted risk of having a specific side effect or any side effect was lower among those with diabetes, with significant reductions in fatigue and headache but no differences in breakthrough infections over participants’ maximum follow-up time. Diabetes medication use did not consistently affect the risk of specific side effects, either using self-reported medication use or using only diabetes medications that were confirmed by pharmacy health insurance claims for people who also reported having diabetes.

Conclusions

People with diabetes reported fewer vaccine side effects than participants not reporting having diabetes, with a similar risk of breakthrough infection.

Trial Registration

ClinicalTrials.gov NCT04368065; https://clinicaltrials.gov/study/NCT04368065
EL D.L. Nº 2.695, DE 1979, ANTE LA INFORMALIDAD URBANA: HACIA LA CONFORMACIÓN DE UN SISTEMA DE REGULARIZACIÓN INTEGRADO
Authors: Reyes Vallejos Felipe
Published: December 2023

La presente investigación tiene por objeto analizar la aplicación del D.L. N° 2.695, de 1979, como herramienta de saneamiento del dominio en asentamientos irregulares. Específicamente, se busca: 1) proveer una nueva aproximación sobre la interacción entre el D.L. N° 2.695, de 1979, y la legislación urbanística, mediante el desarrollo de un enfoque integral del saneamiento urbano (dominial y urbanístico) de asentamientos irregulares; y 2) establecer las características actuales del sistema de regularización de la posesión y constitución del dominio del D.L N° 2.695, de 1979, observando su vinculación con la reciente normativa sobre saneamiento urbanístico de asentamientos irregulares. La investigación se estructura sobre la base de una revisión de la legislación sobre regularización urbanística emergida a partir de la Ley N° 20.234, de 2008, y sus modificaciones, y su impacto en el D.L. N° 2.695, de 1979, junto con la principal doctrina, jurisprudencia administrativa y circulares ministeriales, exponiendo las líneas centrales del sistema de saneamiento dominial en cada periodo. Se afirmará que tras la dictación de la Ley Nº 21.477, de 2022, que introdujo sustantivas modificaciones a la Ley N° 20.234, de 2008, se estructuró un sistema de saneamiento de asentamientos irregulares que encausó el procedimiento de regularización del D.L. Nº 2.695, de 1.979, en el marco del sistema normativo urbanístico general que rige la formación de loteos, al condicionar la regularización de la posesión material a la recepción definitiva de las obras de urbanización, integrando así ambos sistemas de saneamiento.
PERAN PESANTREN AL-MAWADDAH DALAM MENUMBUHKAN JIWA ENTREPRENEUR SANTRI MELALUI PRAKTIK BERWIRAUSAHA (STUDI KASUS PESANTREN AL-MAWADDAH HANGGOSOCO KUDUS)
Authors: Fina Nailil , Andni Riyan
Published: December 2023

Pondok pesantren menjadi salah satu institusi pendidikan yang berperan penting dan ikut andil dalam meningkatkan kualitas SDM. Pesantren dikenal lembaga yang hanya memberikan pengetahuan agama (mengaji) dan akhlaq, serta mencetak generasi alumni memiliki skill entrepreneurship yang baik. Al Mawaddah merupakan salah satu lembaga pesantren di Kudus yang sudah terealisasikannya program entrepreneur. Penelitian ini bertujuan untuk mengetetahui peran pesantren Al Mawaddah dalam menumbuhkan jiwa entrepreneur santri agar mencetak generasi alumni memiliki kemampuan kewirausahaan yang baik. Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan metode penelitian lapangan. Data dikumpulkan melalui wawancara mendalam dan observasi dengan bukti dokumentasi serta diolah dengan tahapan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa pondok pesantren mempunyai peranan yang penting dalam menumbuhkan jiwa kewirausahaan santri, dapat dilihat dari kemandirian secara financial yaitu tidak boleh menerima uang saku dari orangtuanya. Selain itu jumlah 100an alumni yang memiih berwirausaha dan dapat memperkerjakan orang lain. Dengan memperbanyak jenis program dan usaha di pesantren, santri  dapat meningkatkan skill dan menumbuhkembangkan jiwa wirausaha sesuai dengan kemampuan yang akan mereka asah. Dukungan dari berbagai pihak disini  diperlukan seperti pemerintah, masyarakat, kemampuan bakat tiap santri, orang terdekat, modal, terlebih kepada pesantren dalam memberikan motivasi agar semangat para santri tidak naik turun selama proses pembelajaran di pesantren. Oleh karena itu diharapkan para santri memiliki bekal ilmu wirausaha dan tidak buta akan peluang yang ada setelah keluar dari pesantren baik pada dunia kerja online ataupun offline, sekaligus dapat membuka lapangan pekerjaan bagi orang lain.

Kata Kunci: Peran Pesantren, Jiwa Entrepreneur, Praktik Berwirausaha