bluuebunny/crossref_metadata_2025 huggingface dataset:
CUIDADOS DE ENFERMAGEM AO PACIENTE EM RECUPERAÇÃO PÓS CIRURGIA ORTOPÉDICA
Authors: Da Silva Daysiane Vasconcelos , Silva Inês Florêncio de Carvalho , Da Silva Tiago Emanoel Alves
Published: July 2023

A enfermagem tem como objetivo o cuidado as pessoas que necessitam de assistência, estas desde o nascimento até a morte passam pelas mãos da equipe de enfermagem. A fim de prestar o melhor suporte possível, os profissionais de enfermagem se qualificam em diversas áreas distintas, para se tornarem aptos a cuidar de forma eficaz e satisfatória. O pós-operatório ortopédico é repleto de ações prestadas pela equipe de enfermagem a fim de auxiliar na recuperação, bem como, prevenir possíveis complicações. Esta pesquisa tem como objetivo compreender quais são os cuidados que a equipe de enfermagem deve ter para a recuperação de pacientes em pós-operatório de cirurgia ortopédica. A equipe de enfermagem deve ter conhecimento e domínio sobre incisões cirúrgicas e lesões traumáticas para poder oferecer um cuidado específico, tendo como norteador o processo de Sistematização da Assistência de Enfermagem (SAE) para conduzir as ações inseridas no processo de cuidado. Para a construção desse estudo foi realizado uma pesquisa de revisão de literatura, de cunho exploratório, com abordagem qualitativa. Levando a critérios de inclusão artigos científicos de fontes confiáveis, que se encaixaram no tema proposto, publicados entre 2017 a 2023, a partir de materiais criticamente selecionados e lidos na íntegra. Para fins de exclusão foram adotados os seguintes critérios: Artigos científicos que não estejam no idioma português; trabalhos que fujam do tema proposto e aqueles que ultrapassem a margem de 6 anos de publicação, e aqueles que trazem a visão do paciente como foco principal do tema. Os resultados encontrados destacam a importância do planejamento pré-operatório e do papel fundamental do enfermeiro no cuidado ao paciente no período pós-operatório para o sucesso da recuperação do paciente após cirurgia ortopédica e concluem o cuidado com a higiene das mãos, nutrição, administração correta de medicamentos e a orientação aos pacientes sobre a importância da adesão às terapias prescritas e dos cuidados com a incisão cirúrgica, contribuindo para a prevenção de complicações e para o sucesso da reabilitação.
Fatores associados à hesitação vacinal contra a COVID-19 em um município no norte do Brasil
Authors: Pedroza Athos Costa , Silva Felipe Castro Carvalho , Pereira Amanda Araújo , Lopes Ana Paula Marinho
Published: July 2023

A pandemia da COVID-19 impulsionou os debates sobre a necessidade de medidas para conter o seu avanço, como a vacinação. Entretanto, concomitantemente ao desenvolvimento de imunizantes surgiram questionamentos acerca da sua eficácia e segurança, o que expõe a necessidade da discussão relacionada aos fatores que motivam a recusa vacinal. Identificar os fatores associados à hesitação vacinal contra o vírus SARS-CoV-2 e correlacionar com o perfil socioeconômico de indivíduos entre 18 e 65 anos de idade no município de Marabá-PA. O presente estudo caracteriza-se como uma pesquisa de campo, quantitativa, de caráter analítico, exploratório e transversal, realizada na cidade de Marabá-PA, com o apoio de duas Unidades Básicas de Saúde. Após aprovação do Comitê de Ética em Pesquisa, os pesquisadores realizaram uma abordagem pessoal com os participantes que responderam, anonimamente, os questionários semiestruturados com interrogações objetivas. Os dados foram tabulados e analisados com base nas estatísticas descritiva e analítica, com o auxílio dos softwares Microsoft Office Excel 2019 e BioEstat® 5.4. A pesquisa resultou em 169 participantes para compor o estudo. Esses resultados foram organizados em gráficos e tabelas a fim de facilitar a visualização e o entendimento. A análise dos dados permitiu inferir que a preocupação com os efeitos colaterais da vacina associado a fatores socioeconômicos contribui para a hesitação vacinal entre os moradores do interior do norte brasileiro.
Ausência do popular no ensino especializado da música a desvalorização do “tocar de ouvido”
Authors: Caldeira Artur Carlos Azevedo de Saraiva
Published: July 2023

Partindo do princípio de que o curso básico do ensino genérico fornece aos alunos diversas matérias de base para uma formação geral, o curso secundário continua essa formação iniciando-se uma opção por determinada área do conhecimento e a Licenciatura (e graus seguintes) comporta já alguma especialização, pergunto-me porque o Ensino Especializado da Música (cuja designação não inclui o termo “erudita”) apenas contempla nos seus programas repertório erudito e de tradição escrita, numa espécie de especialização precoce ao contrário de uma formação musical de base mais alargada. Será esta especialização o melhor contributo para uma adequada construção basilar de um músico, excluindo outros processos de entendimento e prática musical paralelos ao estudo meramente académico ou intelectual da Música? Trazendo à conversa autores que se debruçam sobre educação formal, informal e não formal e com base na minha experiência enquanto músico, aluno e professor, sugiro a valorização do “tocar de ouvido”.
Modelo teórico para la gestión de la calidad en la educación superior mexicana
Authors: Cuahquentzi Victor Job Paredes , Cuahquetzi Marcelo Paredes , Hernández-Flores Edit , Flores Gabriela Hernández
Published: July 2023

En este artículo se presenta un modelo teórico resultado de una investigación llevada a cabo sobre la calidad de la educación superior en México, en el proceso logramos identificar la parte sustancial que tienen como protagonista los cuerpos académicos de una institución de educación superior, en el desarrollo de estos cuerpos académicos se refleja como mejoran aquellos que reciben estimulación externa y como dando valor a la Instituciones de Educación Superior (IES) a la que pertenecen, en el transcurso de esta investigación nos damos cuenta de cómo a través autopoiesis de manera categórica “esencial” tienen la posibilidad de transitar a un estadio superior hasta llegar a la consolidación y al mismo tiempo el aporte individual y colectivo, apoyando a solventar las variables y factores que son evaluados de manera institucional hasta la excelencia universitaria.
Diseño de interfaz gráficas de usuario para el análisis, diseño, simulación y control de sistemas lineales análisis de sistemas lineales utilizando Matlab
Authors: Sosa Lais Hernández , González Antonio Ochoa , Aciego Carlos Ernesto Díaz , Álvarez Ernesto Pérez , Marín Juan Anzurez , Zavala Salvador Ramírez
Published: July 2023

La mayoría  de los sistemas físicos pueden representarse con modelos lineales o linealizarse para un mejor análisis, diseño e implementación; en el área de control y automatización de procesos resulta de gran importancia y utilidad analizar las características principales de los sistemas lineales, así en el presente trabajo se implementa una aplicación basada en una interfaz gráfica que permite analizarlos, en características como estabilidad, controlabilidad, observabilidad, respuesta en lazo abierto y diseño del controlador/observador cuando el sistema cumpla con las condiciones. Estos aspectos podrían obtenerse directamente mediante las funciones implementadas en el software Matlab®; sin embargo, se requiere conocer y dominar los comandos y la forma necesaria para introducir los datos, por lo que en esta aplicación las funciones se ejecutan internamente sólo presionando botones, permitiendo la introducción de los datos de manera matricial y ofreciendo los resultados de forma clara e intuitiva mediante gráficos y valores explicados. La interfaz diseñada se puede ejecutar en cualquier computadora sin necesidad de tener dicho software instalado.
(In)aplicabilidade do Acordo de Não Persecução Penal (ANPP) sob a ótica dos crimes militares a serem processados na Justiça Militar dos Estados
Authors: Sperka Junior Lauro , Teixeira Rodrigo Kohler
Published: July 2023

O Acordo de Não Persecução Penal (ANPP) é um instrumento consensual e negocial penal para crimes de menor gravidade, sem violência, com penas restritivas de liberdade inferiores a 4 anos. Previsto por resoluções do Conselho Nacional do Ministério Público e incorporado à Lei nº 13.964/2019, o ANPP é um acordo realizado antes do processo criminal, com confissão do crime pelo acusado e estabelece condições a serem cumpridas, como multa, serviços à comunidade ou comparecimento periódico em juízo. O Ministério Público faz a proposta, mas o juiz decide. Existem causas impeditivas e o juiz pode recusar. Se cumprido integralmente, extingue a punibilidade do acusado. Na Justiça Militar, há interpretações divergentes sobre a aplicabilidade do ANPP. Alguns defendem interpretação extensiva e analogia, enquanto outros alegam o silêncio do legislador. Pode haver omissão parcial dos legisladores, pois o art. 28-A do CPP não menciona explicitamente militares federais e estaduais. A aplicação do ANPP aos crimes militares, cuja apuração inicia-se, em regra, na Polícia Militar do Estado do Paraná, por meio de um Inquérito Policial Militar, poderia ser admitida por aplicação subsidiária da legislação processual comum, posto que a igualdade de tratamento entre militares e civis é garantida, com exceções previstas em lei, porém ainda a aplicação do ANPP na Justiça Militar é controversa. A Lei 9.839/99 estabeleceu a inaplicabilidade da Lei 9.099/95 na Justiça Militar. A Súmula nº 18 do Superior Tribunal Militar estabeleceu a inaplicabilidade do ANPP na Justiça Militar da União, porém esta não é vinculante. O Ministério Público Militar emitiu a Resolução nº 126/2022, permitindo sua aplicação apenas em crimes militares que não violem hierarquia e disciplina. A discussão sobre o ANPP na Justiça Militar ainda não está pacificada, devendo ser avaliada caso a caso, com respeito à isonomia.
Existence of solution of a nonlinear elliptic coupled system
Authors: Gutiérrez Milton Milciades Cortez , Broncano José Simeón Quique
Published: July 2023

This paper  is concerned with the  proof of  the existence of solutions for a non linear elliptic coupled system in Sobolev space, more precisely such systems involve non linear partial differential equations of type elliptic.
I4.0 assessment and roadmap: a case study in a medium-sized company in the consumer goods sector
Authors: Gomes Guilherme , Rodrigues Ana Lígia Vieira , Bouzon Marina
Published: July 2023

The aim of this research is to define a maturity assessment model for SMEs and apply it to a company in the consumer goods sector, as well as to outline an I4.0 implementation roadmap considering the company's business strategies. The literature shows that there is a lack of studies focusing on applying maturity assessment models in SMEs, as they are more adherent to the large corporation scenario. Thus, this research assesses the developed maturity models and selects the one that can best be applied to the case study. Through a search in the main literature databases, we listed the main maturity models that can be applied in SMEs. Through an assessment of models and guidelines from other research, we selected the IMPULS maturity model for this case study. After applying the maturity model, the company studied was classified at maturity level 1, that is, the company is considered a beginner. Thus, focusing on the next 3 years of work, a roadmap was designed focusing on the 3 main dimensions with gaps in the assessment.
Análise, otimização e acompanhamento de um serviço de psicologia universitário: uma abordagem baseada em ciência de dados
Authors: Lobato Fabio , Poça Milena , Canto Viviane
Published: July 2023

É inegável a correlação positiva entre saúde mental e desempenho acadêmico. Apesar disso, é patente a escassez de recursos destinados à promoção da saúde mental, sobretudo no contexto universitário.. Destarte, faz-se imperativo a otimização dos parcos recursos a fim de potencializar o impacto das ações neste cenário. Considerando que a Universidade Federal do Oeste do Pará é exemplo desta problemática, com duas psicólogas de referência à frente do Núcleo de Psicologia (NUPSI) da instituição, responsável pela promoção de saúde mental para um público de mais de 8.000 usuários, entre estudantes da graduação e pós graduação; o presente estudo reporta o uso de ciência de dados para otimizar as ações do setor, definindo políticas públicas estudantis mais adequadas para uma Universidade multicampi, localizada no interior da Amazônia, especificamente nas regiões do baixo Amazonas e Tapajós. Usando uma abordagem similar à pesquisa-ação, com fases diagnóstica, prescritiva e segmental, sendo que em todas, foram utilizadas técnicas de análise exploratória e visualização de dados, bem como mineração de textos. Os resultados alcançados, tangíveis e intangíveis, geraram impacto positivo, não só no NUPSI, mas extrapolando para outros setores da instituição. O método de trabalho reportado é escalável, pode ser aplicado a outras Universidades.
Mineração de Processos como Ferramenta para Promoção da Transparência: Oportunidades e Desafios
Authors: Mendes de Araujo Renata , Marques Peres Sarajane , Fantinato Marcelo , Jacoto Unger Adriana , Rodrigues Neubauer Thais
Published: July 2023

A transparência pública possibilita o exercício da democracia tanto pela orientação a melhores práticas de gestão por parte das instituições públicas como pela promoção da participação ativa dos cidadãos na gestão pública. A transparência é uma conduta essencial em um contexto democrático e sua prática deve ser continuamente incentivada e aperfeiçoada, principalmente considerando as possibilidades que emergem de novas tecnologias, incluindo as tecnologias relacionadas à gestão da informação. Neste ensaio, exploramos o potencial da mineração de processos como um agente tecnológico de apoio à transparência pública. A capacidade da mineração de processos em possibilitar a análise visual e analítica dos dados relacionados aos registros de execução de processos no âmbito da administração pública, bem como sua capacidade de permitir modelagem preditiva e prescritiva, traz oportunidades para o entendimento do funcionamento da máquina pública, para monitoramento e análise de seu desempenho, incluindo a proposição de ações para otimização do processo  e para verificação de conformidade com normativas, por parte tanto de órgãos de controle como também dos cidadãos. Nós discutimos oportunidades de uso da mineração de processos para promoção da transparência pública a partir de estudos exploratórios anteriores em dois contextos: na área da saúde (considerando o processo de gestão de produtos de saúde da agência de vigilância sanitária nacional) e na área jurídica (considerando a tramitação de processos jurídicos no maior tribunal do Brasil). Reconhecendo, ainda, que tecnologias são ferramentas paradoxais que trazem tanto facilidades como incongruências, discutimos alguns potenciais desafios para a adoção da mineração de processos para a transparência na administração pública observados a partir dos estudos.
The Relationship Between CACNA2D1 Gene and Subclinic Mastitis in Holstein Breed Cattle
Authors: DALDABAN Fadime , ARSLAN Korhan , AKYÜZ Bilal
Published: July 2023

The CACNA2D1 gene encodes the CACNA2D1 protein and, this protein is involved in the excitation-contraction mechanism of the muscle cells during milk withdrawal, helps the nipples to open and close. Because of this role in physiological mechanism and its relationship with quantitative trait locus (QTL) regions, CACNA2D1 gene is known to be associated with mastitis resistance. In this study, it was aimed to investigate the relationship between different three SNP (C367400T, A496561G and G519663A) on the CACNA2D1 gene, and subclinical mastitis in Holstein breed cattle reared in Develi district of Kayseri province. SNPs were genotyped from DNA samples by PCR-RFLP method. In the study, California mastitis test (CMT) data, and distributions of genotypes of the three SNPs on the CACNA2D1 gene were calculated. In the study, genotype distributions were determined in terms of C367400T, A496561G and G519663A SNPs found on the CACNA2D1 gene according to CMT status. The difference between the C367400T, A496561G and G519663A SNPs was not significant (p>0.05). In the study group examined the Chi-square (χ2) analysis conducted, it was observed that the Holstein cattle were in the Hardy-Weinberg equilibrium (HWE) in terms of C367400T and A496561G SNPs, deviation from HWE for the G519663A SNP (p<0.05). As a result, it was thought that the CACNA2D1 gene and these SNPs should be evaluated with more samples and different mastitis indicator data in studies on mastitis resistance.
Comparação do recobrimento radicular em recessões unitárias utilizando matriz colágena Mucograft® X enxerto autógeno: revisão de literatura
Authors: Matos Flávia Gomes , De Moura Guilherme Bianchine , De Campos Bernardo Oliveira
Published: July 2023

O tratamento de recessões gengivais além de proporcionar maior conforto ao paciente diminuindo a sensibilidade restabelece o posicionamento normal do tecido gengival melhorando a estética. Procedimentos cirúrgicos rápidos e com menor sintomatologia dolorosa seriam ideais na prática clínica para o recobrimento radicular. Dessa forma, biomateriais substitutos a enxertos autógenos estão cada vez mais sendo pesquisados. Assim, o objetivo deste estudo é verificar sob revisão da literatura científica atualizada, artigos clínicos que realizaram o recobrimento radicular em recessões dentais unitárias utilizando do Mucograft® comparativamente aos enxertos autógenos. Para isso, o termo Mucograft® foi utilizado para buscas no Pubmed e Google e 48 resultados foram obtidos. Desses, 9 artigos foram selecionados. 6 estudos avaliaram a porcentagem de recobrimento radicular, enquanto que 2 avaliaram o aumento da faixa de tecido queratinizado e 1 as mudanças histológicas. O uso de Mucograft® demonstrou resultados positivos em relação a capacidade de recobrimento radicular com boa estética e nível de dor pós operatória semelhante ao do obtido pelo enxerto autógeno. As evidências científicas demonstram que o a Matriz Mucograft® é um material promissor, mas comprovações com maior tempo de acompanhamento são necessárias para auxiliar o clínico nas suas escolhas.
INTERNATIONAL BUSINESS AS AN ACTOR IN THE «GREEN» ECONOMY
Authors:   Russian University of Economics named after G. V. Plekhanov, Moscow, Russia, Progunova Lada V. , Shustrov Maxim A. ,   Russian University of Economics named after G. V. Plekhanov, Moscow, Russia
Published: July 2023

Now humanity is fully aware of the environmental problem, which is associated, among other things, with the anthropogenic effect. In this regard, it became necessary to transform radically all spheres of life in order to ensure sustainable development. This trend also affects the economic model of the development of the world. Environmental pollution actualized the problems of limited natural resources and led to an awareness of the limits of growth. The relevance of this research is associated with the special role of environmental and economic factors in the modern world, which influenced the formation and further popularization of the «green» economy phenomenon. This problem acquires particular urgency and relevance in connection with the expansion of the «green» economy concept, as well as players in the field of sustainable development. Thus, international companies have become a new active actor on the «green» agenda, which are actively implementing and creating new forms and tools of «green» growth themselves.
HUBUNGAN PENGETAHUAN DAN PERILAKU MENJAGA KEBERSIHAN GENETALIA EKSTERNA REMAJA PUTRI DENGAN KEJADIAN KEPUTIHAN
Authors: Novita  , Ita Herawati  , Isna Nurmaliani
Published: July 2023

ABSTRAKLatar Belakang : Kesehatan reproduksi remaja merupakan suatu kondisi sehat yang menyangkut sistem reproduksi (fungsi, komponen, dan proses) yang dimiliki oleh remaja baik secara fisik, mental, emosional, dan spiritual (Hidayat, 2013). Kesehatan reproduksi remaja masih menjadi masalah kesehatan yang cukup besar skalanya di Indonesia. Menurut Kesehatan Reproduksi Remaja (KRR) sejak tahun 2000, secara umum didefinisikan sebagai kondisi sehat dan sistem fungsi dan proses alat reproduksi yang dimiliki oleh remaja yaitu laki-laki dan perempuan usia 10 – 24 tahun.Tujuan Penelitian : untuk mengetahui hubungan pengetahuan dan perilaku menjaga kebersihan genetalia eksterna remaja putri dengan kejadian keputihan di SMP Islam Asyafiiyah 06 2018.Metode Penelitian : Metode penelitian ini menggunakan analitik dengan pendekatan cross sectional, yang menjadi sampel dalam penelitian ini adalah seluruh siswi kelas VIII SMP Islam Asyafiiyah.Hasil Penelitian : dari 75 responden didapatkan bahwa responden yang mengalami keputihan fisiologis sebanyak 19 orang (25,3%), dan respondenyang mengalami keputihan patologis sebanyak 56 orang (74,4%). Responden yang memiliki pengetahuan kurang baik sebanyak 45 (60%), responden yang memiliki pengetahuan cukup sebanyak 23 orang (30,7%), dan responden yang memiliki pengetahuan baik sebanyak 7 orang (9,3%). Responden yang mempunyai perilaku buruk sebanyak 61 orang (81,3%), responden yang mempunyai perilaku baik sebanyak 14 orang (18,7%).Keismpulan dan Saran : dari hasil penelitian yang didapatkan menunjukkan bahwa adanya hubungan antara pengetahuan dan perilaku remaja putri dengan kejadian keputihan di SMP Islam Asyafiiyah 06.
Parental Monitoring and Engagement of Secondary School Students During Covid-19 Lockdown in Kakoba Ward, Mbarara City South, Uganda
Authors: Twesigye Mackey , Barigye Enock , Tibanyendera Basil
Published: July 2023

The purpose of this study was to investigate parental monitoring and engagement of secondary school students during the COVID-19 Lockdown in Kakoba ward, Mbarara City, Uganda. The study adopted both descriptive and correlational research designs for data collection and analysis. Information was collected from 93 respondents using a questionnaire and interview guide. The factor analysis of items of parental monitoring data generated three factors: parents’ study monitoring, parents’ network monitoring, and parents’ activeness in the student’s studies. The informants’ views provided more insights into the factors, including timetable, checking on the work covered and giving quiz gave more insights. Factor 1- Parents’ study monitoring mirrored networking with other parents. Factor 2 - Parents’ network monitoring - attending classes with children while Factor 3 - Parents’ activeness in studies. The study rejected the null hypothesis that parental monitoring does not significantly influence the engagement of secondary school students. This calls for the strengthening of the relationship between parental monitoring and engagement of secondary school students
Analysis of dynamic methods for calculating NPP building structures
Authors: Korotkov V. A.
Published: July 2023

Introduction. The present article concerns the seismic performance of various building structures, including NPP objects. The provided materials generalize the results of the author’s longstanding work connected with the dynamics of building structures.

Aim. To analyze the seismic performance of various building structures, including NPP objects, and represent the author’s material on the dynamics of building structures.

Materials and methods. The presented materials include a definition of the dynamics concept, computational modeling of dynamic processes, main correlations of dynamic analysis methods, and a description of impacts (accelerograms). In addition, the concepts of resonance and vibration diagnostics in the dynamic analysis, assessment of the building strength and stability, as well as the description of applied software systems are provided. Some of the presented materials are characterized by the scientific novelty. The following methods were used in the study. The method of nonclassical modal superposition for determining the response of a structure under dynamic impacts together with floor response spectra were presented by the author at the ABAQUS (SIMULIA) International Conference in Barcelona, 2011. The essence of the method consists in the reliable account for a “soil” damper, modeling the energy outflow into the soil during the vibrations of a building, which ensures reliable results. A fundamental solution for accounting the ductility of the foundation slab under seismic impacts was applied. This method ensures the seismic response of the structure to be reliably determined, as well as the floor response spectra to be obtained in the conditions of the aircraft crashing for buildings, whose impact on the equipment is transmitted through the foundation slab. Additionally, the method of accounting the dynamic characteristics of building fragments (floor/ wall), obtained using the vibration diagnostic results, was applied to verify computational models, as well as to analyze the strength and floor response spectra. The appendix includes the realistic test problem of the seismic analysis, developed by the author.

Results. The provided materials generalize the results of the author’s longstanding work in the field of NPP building structures. In addition to the scientific novelty, the materials are widely applied in the development of NPP designs both in the Russian Federation and abroad.

Conclusion. The materials, presented in the article, can be used to prepare the “Introduction to Dynamics” lecture course, including, for newcomer countries that are at the beginning of the nuclear facility (NF) construction.
An Afrocentric Perspective on Knowledge
Authors: Tlali Tebello
Published: July 2023

Central to education is the development and dissemination of knowledge even in the context of the COVID-19 pandemic. However, such knowledge has to be relevant and in harmony with the context for which it is meant. The contention in this chapter is that in the age of fourth generation, Afrocentric knowledge should still form a foundation upon which African education is transformed. Innately related to Afrocentric education is the African indigenous knowledge system (AIKS), which represents the totality of all knowledge and practices used to manage the indigenous socio-economic, spiritual, and ecological facets of life. Based on a critical literature review, this chapter sought to foster diversity and inclusion by providing an Afrocentric conceptualisation of knowledge and pedagogy and finding a middle ground between indigenous and cosmopolitan pedagogies as a backdrop for curriculum transformation.
Immunoassay Detects Salivary Anti-SSA/Ro-52 Autoantibodies in Seronegative Patients with Primary Sjögren’s Syndrome
Authors: Kamounah Sarah , Tayob Nabihah , Chiang Samantha , Wei Fang , Park Jin Kyun , Kwon Hyun Mi , Feng Ziding , Chia David , Pedersen Anne Marie Lynge , Song Yeong Wook , Wong David T W
Published: July 2023

The diagnostic work-up for Sjögren’s syndrome is challenging and complex, including testing for serum autoantibodies to SSA/Ro and a labial salivary gland biopsy. Furthermore, the diagnosis is often delayed. In this study, we tested the hypothesis that anti-SSA/Ro autoantibodies are detectable in the saliva of patients with primary Sjögren’s syndrome (pSS) because the disease affects the salivary glands, and these autoantibodies display greater discriminatory performance in saliva than in serum. SSA/Ro-52 Ags were used to develop what is, to our knowledge, a novel quantitative electrochemical-based immunoassay: the electric field–induced release and measurement (EFIRM) platform. The clinical utility was determined by measuring salivary anti-SSA/Ro-52 autoantibodies in patients with pSS and sicca (n = 34), patients without pSS with sicca (n = 35), and healthy subjects (n = 41). The statistical analysis of discrimination included the area under the receiver operating characteristic curve. Salivary anti-SSA/Ro-52 autoantibodies were measured in 94% (32 of 34) of patients with pSS with 85% (29 of 34) seropositivity. Four of the five seronegative patients with pSS had EFIRM-measurable anti-SSA/Ro-52 autoantibodies in saliva. Additionally, 60% (21 of 35) of the seronegative patients without pSS who had sicca had EFIRM-detectable SSA/Ro-52 autoantibodies in saliva, indicating the onset of autoimmune disease. Two of the 41 healthy control subjects had EFIRM-detectable SSA/Ro-52 autoantibodies in their saliva. Salivary SSA/Ro-52 autoantibodies significantly discriminated patients with pSS or patients with the initial stage of autoimmune disease from healthy subjects with an area under the receiver operating characteristic curve of 0.91. Our findings suggest that the proposed saliva SSA/Ro-52 immunoassay improves early and accurate diagnosis of seronegative patients with pSS and patients with early-onset autoimmune disease.
A Pesquisa em Teletrabalho na Administração Pública no Brasil: uma Revisão no Catálogo de Teses e Dissertações (CTD/Capes)
Authors: José Cavalcanti Silva Júnior Marçal , José de Sousa Washington
Published: July 2023

O teletrabalho, primeiramente adotado em empresas privadas, recentemente passou a ser implantado nas organizações públicas. Esta revisão objetiva sistematizar interesses e objetos da pesquisa em teletrabalho na Administração Pública brasileira – com base em inventário no Catálogo de Teses e Dissertações da Capes – intentando definir agenda de pesquisa e retroalimentar sistemas congêneres. Utilizou-se o descritor “teletrabalho” com filtro em Ciências Sociais Aplicadas/Administração Pública. Os resultados são, na totalidade, de pesquisas realizadas em cursos de mestrado, majoritariamente em universidades públicas. A análise das abordagens metodológicas revela predomínio de procedimentos qualitativos. Prevalecem pesquisas no nível federal, em instituições públicas de ensino e provenientes da região Sudeste, abordando a implantação do teletrabalho e seus impactos, focando vantagens, desvantagens, desafios e potencialidades. Evidencia-se forte influência da pandemia de covid-19 no interesse pelo tema. Constatou-se ausência de pesquisas na esfera municipal e em órgãos do Poder Legislativo.
Narrativas pedagógicas da Educação Física em tempos de precariedade
Authors: Kirk David
Published: July 2023

Há uma prevalência crescente de problemas de saúde mental e bem-estar entre crianças e jovens há mais de duas décadas no Reino Unido, situação exacerbada pela pandemia e que certamente perdurará além dela devido a um aumento exponencial da economia gig. As incertezas e a instabilidade que o trabalho gig introduzem na vida das pessoas as deixam doentes e produzem precariedade. Neste contexto, a questão é como a Educação Física deve responder à crescente precariedade? As narrativas dominantes da Educação Física, nos últimos 50 anos, têm sido a preparação para a vindoura sociedade do lazer (que nunca chegou) e a luta contra a obesidade. Embora uma abordagem de prevenção de riscos para a Educação Física como promoção da saúde possa permanecer importante, aulas baseadas em Atividade Física Moderada a Vigorosa (AFMV) podem não ser o que crianças e jovens que sofrem de doença emocional precisam. O artigo defende pedagogias afetivas informadas pela salutogênese como uma resposta apropriada à precariedade. Termina com uma breve revisão das formas pelas quais a precariedade têm sido utilizada na literatura da Educação Física e da Pedagogia do Esporte, oportunidade para argumentar que o conceito, apesar de sua grande importância, ainda não atingiu massivamente os estudiosos de nosso campo.
Implementation of Problem-Based Learning: What is the Influence on Students' Reasoning Ability in Elementary Schools?
Authors: Rahayu Dela Tri , Wulandari Fitria
Published: July 2023

This study aimed to determine the effect of applying the PBL learning model on the reasoning abilities of fourth-grade elementary school students Muhammadiyah 1 Krian. Types of experimental research and using one group pre-test-post-test design method. The population in this study were 23 fifth-grade students at SD Muhammadiyah 1 Krian. The researcher used a saturated sampling technique because population sizes were small. Reasoning ability data was obtained from essay tests before and after the application of PBL. Then the study results were analyzed using descriptive statistical techniques and the N-Gain test using the SPSS version 26 software. The results of this analysis indicate the reasoning ability of the pre-test post-test results showed a significant difference between the average value of the pre-test (63.26) and post-test (82.74), and. those using the N-Gain test obtained an average of 0.52 which indicates the moderate category, so using this PBL learning model can affect the reasoning abilities of elementary school students.
Assessment of the impacts of cloud chemistry on surface SO2 and sulfate levels in typical regions of China
Authors: Lu Jianyan , Gong Sunling , Zhang Jian , Chen Jianmin , Zhang Lei , Zhou Chunhong
Published: July 2023

Abstract. A regional online chemical weather model, Weather Research and Forecasting (WRF)/China Meteorological
Administration Unified Atmospheric Chemistry Environment (CUACE), is used to assess
the contributions of cloud chemistry to the SO2 and sulfate levels in
typical regions of China. Upon comparison with several time series of in situ
cloud chemical observations on Mountain Tai in Shandong Province of China,
the CUACE cloud chemistry scheme is found to reasonably reproduce the
observed cloud consumption of H2O2, O3, and SO2 and the
production of sulfate, and it is consequently used in the regional assessment
of a heavy pollution episode and monthly average of December 2016. During
the cloudy period in the heavy pollution episode, sulfate production increased by 60 %–95 % and SO2 production reduced by over 80 %. The cloud
chemistry mainly affects the middle and lower troposphere below 5 km as well
as within the boundary layer, and it contributes significantly to the SO2
reduction and sulfate production in central-east China. Among these four
typical regions in China, the Sichuan Basin (SCB) is the most affected by the
cloud chemistry, with an average SO2 abatement of about 1.0–10.0 ppb
and sulfate increase of about 10.0–70.0 µg m−3, followed by the Yangtze
River Delta (YRD) and the southeast of the North China Plain (NCP), where SO2
abatement is about 1.0–5.0 ppb and sulfate increase is about 10.0–30.0 µg m−3. However, the cloud chemistry contributions to the Pearl River
Delta (PRD) and the northwest of the NCP are not significant due to lighter
pollution and less water vapor than the other regions.
Contemporary biodiversity pattern is affected by climate change at multiple temporal scales in steppes on the Mongolian Plateau
Authors: Li Zijing , Li Zhiyong , Tong Xuze , Dong Lei , Zheng Ying , Zhang Jinghui , Miao Bailing , Wang Lixin , Zhao Liqing , Wen Lu , Han Guodong , Li Frank Yonghong , Liang Cunzhu
Published: July 2023

Abstract. Present and historical climate conditions jointly determine contemporary
biodiversity patterns and ecosystem functions. However, it remains unclear
how contemporary climate and paleoclimate changes together affect the three
dimensions of biodiversity (i.e., taxonomic diversity, functional diversity
and phylogenetic diversity) and their relationship with ecosystem functions.
Here, we assess the impact of current climate, paleoclimate and its
anomalies on contemporary biodiversity and ecosystem functions. We estimated
the taxonomic, functional and phylogenetic diversity of grassland on the
Mongolian Plateau using vegetation survey data and trait information. We
then used random forest and structural equation models to assess the
relative importance of the present, the Mid-Holocene and the Last Glacial
Maximum climate as well as paleoclimate changes as determinants of diversity
and aboveground biomass. Our results showed that paleoclimate changes and
modern climate jointly determined contemporary biodiversity patterns, while
community biomass was mainly affected by modern climate, namely the aridity
index. Modern aridity and temperature were two major influences on all three
dimensions of biodiversity. Mid-Holocene climate anomalies had a strong
effect on species richness and phylogenetic diversity, while functional
diversity had mainly been affected by temperature anomalies since the Last
Glacial Maximum. These findings suggest that contemporary biodiversity
patterns may be affected by processes at divergent temporal scales. Our
results show that simultaneously exploring the response of the three
dimensions of biodiversity in different periods of climate change and the
theoretical framework for its impact on community biomass is helpful to
provide a more comprehensive understanding of patterns of biodiversity and
its relationship with ecosystem functions.
An empirical model to calculate snow depth from daily snow water equivalent: SWE2HS 1.0
Authors: Aschauer Johannes , Michel Adrien , Jonas Tobias , Marty Christoph
Published: July 2023

Abstract. Many methods exist to model snow densification in order to calculate the depth of a single snow layer or the depth of the total snow cover from its mass. Most of these densification models need to be tightly integrated with an accumulation and melt model and need many forcing variables at high temporal resolution. However, when trying to model snow depth (HS) on climatological timescales, which is often needed for winter tourism-related applications, these preconditions can cause barriers. Often, for these types of applications, empirical snow models are used. These can estimate snow accumulation and snowmelt based on daily precipitation and temperature data only. To convert the resultant snow water equivalent (SWE) time series into snow depth, we developed the empirical model SWE2HS. SWE2HS is a multilayer densification model which uses daily snow water equivalent as sole input. A constant new snow density is assumed and densification is calculated via exponential settling functions. The maximum snow density of a single layer changes over time due to overburden and SWE losses. SWE2HS has been calibrated on a data set derived from a network of manual snow stations in Switzerland. It has been validated against independent data derived from automatic weather stations (AWSs) in the European Alps (Austria, France, Germany, Switzerland) and against withheld data from the Swiss manual observer station data set which was not used for calibration. The model fits the calibration data with root mean squared error (RMSE) of 8.4 cm, coefficient of determination (R2) of 0.97, and bias
of −0.3 cm; it is able to achieve RMSE of 20.5 cm, R2 of 0.92, and bias of 2.5 cm on the validation data set from automatic weather stations and
RMSE of 7.9 cm, R2 of 0.97, and bias of −0.3 cm on the validation data set from manual stations. The temporal evolution of the bulk density can be reproduced reasonably well on all three data sets. Due to its simplicity, the model can be used as post-processing tool for output of any other snow model that provides daily snow water equivalent output. Owing to its empirical nature, SWE2HS should only be used in regions with a similar snow climatology as the European Alps or has to be recalibrated for other snow climatological conditions. The SWE2HS model is available as a Python package which can be easily installed and used.
Cell-free synthesis of proteins with selectively 13C-labelled methyl groups from inexpensive precursors
Authors: Van Raad Damian , Otting Gottfried , Huber Thomas
Published: July 2023

Abstract. The novel eCell system maintains the activity of the entire
repertoire of metabolic Escherichia coli enzymes in cell-free protein synthesis. We show
that this can be harnessed to produce proteins with selectively
13C-labelled amino acids from inexpensive 13C-labelled precursors.
The system is demonstrated with selective 13C labelling of methyl
groups in the proteins ubiquitin and peptidyl-prolyl cis–trans isomerase B. Starting
from 3-13C-pyruvate, 13C-HSQC cross-peaks are obtained devoid of
one-bond 13C–13C scalar couplings. Starting from
2-13C-methyl-acetolactate, single methyl groups of valine and leucine
are labelled. Labelling efficiencies are 70 % or higher, and the
method allows us to produce perdeuterated proteins with protonated methyl
groups in a residue-selective manner. The system uses the isotope-labelled
precursors sparingly and is readily scalable.
Identifying mountain permafrost degradation by repeating historical electrical resistivity tomography (ERT) measurements
Authors: Buckel Johannes , Mudler Jan , Gardeweg Rainer , Hauck Christian , Hilbich Christin , Frauenfelder Regula , Kneisel Christof , Buchelt Sebastian , Blöthe Jan Henrik , Hördt Andreas , Bücker Matthias
Published: July 2023

Abstract. Ongoing global warming intensifies the degradation of permafrost. Permafrost
thawing impacts landform evolution, reduces freshwater resources, enhances
the potential of natural hazards and thus has significant socio-economic
impacts. Electrical resistivity tomography (ERT) has been widely used to map
the ice-containing permafrost by its resistivity contrast compared to the
surrounding unfrozen medium. This study aims to reveal the effects of
ongoing climate warming on mountain permafrost by repeating historical ERT
and analyzing the temporal changes in the resistivity distribution. In order
to facilitate the measurements, we introduce and discuss the employment of
textile electrodes. These newly developed electrodes significantly reduce
working effort, are easy to deploy on blocky surfaces and yield
sufficiently low contact resistances. We analyze permafrost evolution on
three periglacial landforms (two rock glaciers and one talus slope) in the
Swiss and Austrian Alps by repeating historical surveys after 10, 12 and 16 years, respectively. The resistivity values have been significantly reduced
in ice-poor permafrost landforms at all study sites. Interestingly,
resistivity values related to ice-rich permafrost in the studied active rock
glacier partly increased during the studied time period. To explain this
apparently counterintuitive (in view of increased resistivity) observation,
geomorphological circumstances, such as the relief and increased creep
velocity of the active rock glacier, are discussed by using additional
remote sensing data. The present study highlights ice-poor permafrost
degradation in the Alps resulting from ever-accelerating global warming.
Role of Socio-Demographic Factors in Codependency of Spouses of Substance Users
Authors: Abid Ayesha , Suneel Ivan
Published: July 2023

Codependency is considered to be a dysfunctional form infused with the extreme focus outside oneself. Spouses of male substance abusers derive the sense of purpose from the marital relationship, while neglecting their own self-esteem, personal life, self-worth and autonomy. It not only affects their psychological health but is also varied by a number of sociodemographic factors that may contribute to the functionality of spouses. The study aims to examine the relationship between demographic characteristics and codependency of spouses of substance users. Demographic characteristics included education of female spouses, types of substance abuse taken by the male spouses, family system, and profession of female spouses and socio-economic status. There was no significant correlation between the demographic characteristic however there was a significant positive correlation between age, duration of marriage and duration of substance abuse of male spouse. There was also a significant positive correlation between Education and socio-economic status, psychological and medical issue. The patterns uncovered showed to be consistent with the literature and paved way for future research.
Theoretical frameworks toward a nutraceutical approach to treating PTSD
Authors: David A Dawson
Published: July 2023

This literature review examines theoretical frameworks related to applying the principles of biomolecular psychology and psychoneuroimmunology to devise a nutraceutical protocol utilizing phytochemicals for the treatment of posttraumatic stress disorder with a particular focus on modulating the endocannabinoid system through the utilization of molecules inherent in chemovars of Cannabis sativa. It provides a psychosocial overview of posttraumatic stress disorder and the historically controversial and noncontroversial nature of the biologically derived molecules that have demonstrated efficacy in addressing the effects major stressors have on the biomolecular mechanisms that cause mood disorders that manifest themselves as symptoms of PTSD.
The demographic decline of the population of the Republic of Moldova. Factors and consequences
Authors: Sainsus Valeriu , Matei Constantin , Postică Maia
Published: July 2023

The demographic decline affects the existence of the state perspective, compromises the economic development, the well-being of the whole society, a phenomenon that has the characteristics of a latent demographic crisis. Factors are interconnected and have a significant impact on changes in demographic structure (age, gender). Demographic aging has mainly affected rural and urban areas, reaching maximum levels of over 18%, and population losses reach 30% for some administrative units.
Control and state supervision of waste management DOI: https://doi.org/10.53486/9789975155649.45
Authors: Pascal Mihaela
Published: July 2023

Waste management is one of the important issues facing the Republic of Moldova in environmental protection activities. For the purpose of exercising state control and supervision of waste management, including waste products subject to the manufacturer's extended liability regulations, the Environmental Protection Inspectorate carries out a series of activities focused on achieving the objectives and actions set to ensure a high level of surveillance and protection. the environment, the public interest, and the ecological security of the state. However, waste governance authorities do not demonstrate adequate responsibility for effective policy implementation and management, and paper-based reforms are hampering implementation.
Money as the object of philosophical analysis
Authors: Ţurcan Galina
Published: July 2023

Object of philosophical analysis, money is one of the most controversial elements of culture. Money influences not only the economic life, but also the social life of a person. Philosophy had and continues to have a great contribution to the research of money in various aspects. The aim of the paper is to show the place and role of the philosophy, of the philosophy of money, in particular, for researching the essence of money.
New communication technologies: opportunities and challenges
Authors: Bîrsan Svetlana , Cepraga Lucia
Published: July 2023

The explosive development of new communication technologies and their widespread expansion have led to new concerns in interpersonal communication. New technologies involve useful tools for development and communication, but also new challenges, as adapting to new tools and ways of communication causes changes in form and substance at the overall level. In addition to the enormous possibilities that the emergence of new communication technologies has opened up at the communication level, numerous problems have arisen following their introduction. In other words, some acute problems related to the storage and management of information both inside and at the interface with the outside have been solved, but the introduction of new technologies has led to significant changes in configuration, climate and communication networks in organizations / institutions etc. Last but not least, there has been a need for people to adapt "on the fly" to new configurations and characteristics. New communication technologies are combined with other trends at the macrosocial level: globalization, intercultural communication, the decline of consumption patterns, the accelerated evolution of markets, changing lifestyles. The complex of trends that indicate global changes will influence the future and life in organizations / institutions. Challenges for communicators are linked to their ability to anticipate change from the outside and to proactively introduce change adaptation measures. Basically, communication has become the main variable for survival, longevity and institutional health: the development of a human team depends on its development.