bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern approaches to surgical and postsurgical medical management of patients with endometriosis
Authors: В. В. Камінський  , Т. Ф Татарчук  , І. З. Гладчук  , М. Мюллер
Published: December 2017

December 8, 2016 in Kyiv Advisory Board was held related to modern approaches to surgical and postsurgical medical management of patients with endometriosis. Endometriosis is a chronic estrogen-dependent gynecological disease which requires a life-long management plan with the goal of maximizing the use of medical treatment and avoiding repeated surgical procedures. The disease management tactics in patients with endometriosis are determined by the clinical symptoms and includes observation, medical treatment, surgical treatment (conservative, radical), using of the assisted reproductive technologies. To prevent endometriosis recurrence it is reasonable to use a combined approach – surgical methods and hormonal therapy.In resolution surgical tactics of management of patients with endometriosis is described in detail based on clinical symptoms and appropriate conditions for this intervention, according to the unified clinical protocol “Management of patients with genital endometriosis” approved by Order of Ministry of Health of Ukraine No. 319 dated April 06, 2016.Postsurgical prevention of endometriosis recurrence is an important stage of management of patients with endometriosis, as regardless of the proven efficacy of the surgical treatment, a risk of endometriosis lesions and pain recurrence is exist.As noted in the resolution, currently no clear criteria for endometriosis recurrence evaluation are available. The hormonal therapy may maintain the positive effect of the surgical treatment for a long time and may minimize the risk of pain and endometrioid lesions recurrence. For secondary prevention of endometriosis recurrence and associated pain long-term hormonal therapy is recommended (> 6 months). A surgeon plays a key role in prescription of postsurgical medical treatment: he/she determines its strategy for the first 6 months after the surgery in alignment with the outpatient physician.To treat the women with endometriosis and infertility, the surgeon should have the appropriate skills and experience. Cooperation with the centers of reproductive medicine is also mandatory. In persistent infertility (failure of long-term therapy) of non-defined origin and suspected endometriosis (presence of pain syndrome), it is reasonable to perform the laparoscopy to rule out the endometriosis as a cause of infertility and its surgical treatment. After surgery, the patients with the reproductive plans are recommended to prescribe dienogest for 3 months and in case of infiltrating endometriosis forms – at least for 6 months to minimize the inflammatory process. As its noted in resolution medical and surgical methods of endometriosis treatment should not be considered as competitive but as compatible, which increase the treatment efficacy and improve the disease prognosis.
Endometrial hyperplasia: there are more questions than answers
Authors: А. Н. Григоренко  , А. Б. Гордийчук
Published: December 2017

Endometrial hyperplasia is a histological diagnosis. It refers to hormone-dependent diseases, which are treated with various hormonal drugs and surgical methods. At the same time, the method and timing of monitoring of the effectiveness of treatment depend on the initial morphological diagnosis.In recent years, there have been many changes in the classification, diagnosis and treatment of this disease. So, in 2014, a new international classification was developed by the International Agency for Research on Cancer and the World Health Organization, based on the identification of atypical cells in endometrial hyperplasia with modern molecular genetics and immunohistochemical methods. According to this classification, only two categories of endometrial hyperplasia are distinguished: with and without atypia. At the same time, the introduction of this classification in Ukraine is impossible without the involvement of morphologists and the development of a unified diagnostics strategy.The goal of the treatment of endometrial hyperplasia is the relief of symptoms (abnormal uterine bleeding, pain) and the prevention of relapses, and most importantly the timely detection of concomitant invasive endometrial cancer. During the diagnostic search for endometrial hyperplasia at any age, alertness for cancer must be present. Currently, the search for safer methods of timely detection of endometrial cancer early stages has been given great attention, but due to imperfect methods, there are still difficulties in diagnosing and predicting benign and malignant proliferative processes.An unfavorable outcome in the inadequate management of patients with benign tumors and uterine hyperplastic processes, especially when combined, is radical surgical treatment − hysterectomy. And only the mutual work of morphologists and gynecologists, which are aware of the difficulties in diagnosis and treatment, namely the presence of resistance to certain pharmacological groups of drugs in a number of women, will not allowed to lose time and review the strategy of management for that patients for applying the reasonable methods of treatment.
Incidence and spectrum of chromosomal abnormalities detected in married couples with early losses of pregnancy
Authors: М. П. Веропотвелян  , Л. Г. Шаповаленко  , О. С. Саваровська
Published: December 2017

The aim of the study was to establish the incidence and spectrum of chromosomal abnormalities (CA) in married couples (MC) with sporadic and habitual early pregnancy losses (EPL) inhabiting south-east and central regions of Ukraine.Materials and methods: A cytogenetic study of 1869 women, 1788 men, and 1781 married couples (a total of 3657 individuals) with EPL was performed separately.Results: In 344 cases (9.4%), the patients’ karyotype contained various types of chromosomal rearrangements. Reciprocal translocations were found in 153 cases (48.3% of the total number of CA detected in women and men; in the case of couples with EPL the frequency of translocations was 4.1%), while in women – 84 (44.4% of all CA) cases, in men – 69 (44.5% of all CA), and in married couples – 6 (28.6%).Robertson’s translocations were found in 13 cases (9 in women and 4 in men), which amounted to 3.8% of all CA; their frequency in couples with EPL was 0.35%.Pericentric inversions were found in 159 cases (46.2% of the total number of CA), in couples with EPL their frequency made 4.3%, while in women – 82 (43.4% of all CA) cases and in men – 77 (49.7% of all CA).Pericentric inversion of chromosome 9 was detected in 65 cases, which is 40.89% of the total number of pericentric inversions and 18.89% of the total number of CA. Paracentric inversions in the karyotyped families with EPL are not detected by our study.Five cases with a mosaic karyotype of 45, Х/46, ХХ (1.5% of all CA), 4 cases with an isochromosome – 45,Х, i(Xq), 2 cases with a mosaic karyotype of polysomy in X (47, XXX / 46, XX), 3 cases of dysomia X – Klinefelter syndrome, 3 deletions of the terminal portion of short arm 46, X, del(X) (p21→pter).Conclusion: The frequency of CA in women with EPL was 8.5%, in men – 6.4%, and totally in all karyotyped parents – 7.5%, which does not differ from the incidence of CA in couples who have miscarried in other populations.
Concomitant endometriosis and leiomyoma in women of reproductive age
Authors: М. Б. Запорожченко  , А. В. Сидоренко  , Д. Ю. Парубина
Published: December 2017

Endometriosis and leiomyoma commonly co-exist inside one uterus. Specialized surgical centers report detection frequency of comorbid endometriosis during surgery or laparoscopy that varies from 20 to 87% in patients with symptomatic fibroids.In authors practice the histological study of surgery samples from patients diagnosed with symptomatic fibroids (113 hysterectomies) revealed concomitant endometriosis in 26.5% cases.Clinical and morphological analysis showed that in patients with multiply fibroids, large volumes or submucous myomas comorbid adenomyosis doesn’t interfere significantly with the clinic course. But in cases of small-size solitary intramural or subserosis fibroids the clinic of symptomatic myomas is determined by the comorbid adenomyosis of diffuse-nodular or diffuse-lesion forms and 2–3 stages.Thus, endometriosis associated with leiomyomas causes more severe course of comorbidity. Patients with symptomatic fibroids are exposed to higher risk of endometriosis development, which must be kept in mind when planning the surgery treatment. Authors propose to enhance laparoscopic myomectomy with target revision of pelvis to reveal possible endometriosis, because laparoscopy provides the best opportunity to visualization of endometriosis lesions.The choice of pharmacotherapy of concomitant uterine pathology is limited. Gonadotropin-releasing hormone agonists is the only currently available group of drugs that labeled both for the treatment of endometriosis and fibroids. Selective progesterone-receptor modulator ulipristal acetate due to its unique antiproliferative and selective proapoptotic effect on the leiomyomas cellular component is very promising in the uterine-sparing therapy of myomas. In addition, it has pharmacodynamic effects on the endometrium, including antiproliferative effects that may contribute to the treatment of endometriosis. Clinical trial of ulipristal on this indication is ongoing (NCT02213081). For the present, in the absence of approved algorithms for the treatment of co-morbid pathology, the individual approach with combining preparations of different classes is relevant.
Pathogenetic therapeutic and preventive measures in women of risk group of isthmicocervical incompetence
Authors: Л. Б. Маркін  , Т. Ф Татарчук  , К. Л. Шатилович
Published: December 2017

The article considers the problem of isthmicocervical incompetence (ICI) as one of the leading factors in the genesis of premature termination of pregnancy. As noted, the frequency of this pathology in the population among pregnant women reaches 15%. The results of the study are presented, the purpose of which was to study the clinical effectiveness of the use of the drug Biolectra Magnesium Fortissimum in preconception prevention of ICI in women with undifferentiated connective tissue dysplasia on the background of a magnesium deficiency.The study involved 50 women at risk of ICI (hypomagnesemia, decrease in the index of resistance in the small arteries of cervix uteri (CU), ultrasound signs of connective tissue dysplasia). The age of women ranged from 20 to 40 years. Most subjects had clinical symptoms of magnesium deficiency: tachycardia occurred in 28%, sleep disorders in 24%, general fatigue in 20%, constipation in 18%, paresthesia in 36%, muscle spasms in 18% of cases.The mean magnesium concentration in the blood plasma of the patients was 0.74 ± 0.03 mmol/l. The conducted studies showed a significant decrease in the index of resistance in small arteries of CU in 86% of women, which indicated the presence of morphofunctional deficiency of CU. Also, in 78% of women, echographic examination revealed the presence of collagenopathy.To correct the magnesium deficiency in the pregestation period, women were prescribed the drug Biolectra Magnesium Fortissimum (Hermes Arzneimittel GmbH, Germany) for 1 effervescent tablet once a day for 10 days with a break of 2 weeks for 3–4 months. After completion of the course of treatment, in most cases there was a lack or decrease in the frequency and intensity of symptoms of magnesium deficiency symptoms. The gradient of magnesium level increase after a 3-month therapy was 0.14 ± 0.03 mmol/l. Residual phenomena of paresthesia occurred only in 10% of women, muscle cramps – in 8%. In 60% of women, there was an approximation of the blood flow resistance in the small arteries of CU (RI 0.63 ± 0.03) and in 64% of cases the ultrasonic examination of CU revealed an increase in the reflectivity of the organ, which indicating stabilization of collagen structures, changes in the morphofunctional state of CU, normalization of hemodynamic processes in the organ.Thus, the use of drug Biolectra Magnesium Fortissimum in magnesium deficiency provided an effective correction of hypomagnesemia, positively influenced the morphofunctional state of CU, which helped prevent the complication of pregnancy in 80% of cases.
The role of endothelial dysfunction in the development of clinical manifestations of climacteric syndrome in premenopausal women
Authors: О. В. Занько  , Л. В. Болгова  , Н. В. Коваленко  , Т. Ф. Татарчук  , Н. В. Яроцька
Published: December 2017

The aim of the study was to determine the state of vascular microcirculation in women with clinical manifestations of climacteric syndrome (CS) and to study the efficacy of using oral forms of L-arginine in its treatment.Materials and methods. 62 patients aged 40–50 years were examined: 30 patients with clinical manifestations of CS and 32 patients without signs of CS. The severity of CS was assessed using the menopausal rating scale (MRS). The study of hormonal homeostasis consisted in determining the levels of estradiol, FSH, LH, TSH and prolactin. The evaluation of the state of the vessels of the microcirculatory bed was carried out with the help of a test with «reactive hyperemia» and laser doppler fluorometry (LDF) with occlusion test. All patients with signs of endothelial dysfunction were prescribed an oral form of L-arginine –Valargin in a dose of 1 tablet per day during 1 month, after which a repeated examination of the state of the vascular endothelium was carried out.Results. When comparing the hormonal status, a decrease in the average level of estradiol and an increase in the average FSH indices in the main group were found in comparison with the control group. Based on the results of the test with «reactive hyperemia», a significantly higher level of pathological response to occlusion was revealed in comparison with the control group.In addition, a significant direct correlation was found between the level of estrogens and the index reflecting the activity of endotheliocytes. 1 month after Valargin application the degree of CS on the MRS scale decreased from 14.7 ± 1.5 to 8.6 ± 1.3 points.Conclusion. In patients with clinical manifestations of CS endothelial dysfunction is more reliably detected. This requires additional testing and the use of preventive measures aimed at preventing cardiovascular pathology. The efficacy of oral forms of L-arginine in adequately high doses, in particular Valargin, in the treatment of endothelial dysfunction and the positive effect of this therapy in patients with CS is proved.
Melatonin: influence on life quality and personality profile of women of late reproductive and pre-menopausal age with endometrial pathology
Authors: С. М. Корниенко  , Ю. В. Давыдова
Published: December 2017

The aim of the work. To investigate the relationship of melatonin with the quality of life and the profile of the personality of women of late reproductive and premenopausal age with the pathology of the endometrium.Materials and methods. 45 women aged 36–55 years with endometrial diseases were examined. All patients underwent hysteroscopy. The personality profile was assessed using the FPI test. To study the quality of life, the SF-36 questionnaire was used. The data was processed using the Spearman rank correlation.Results. As a result of the correlation analysis of data on melatonin concentration and SF-36 scales, our study found that the value of melatonin did not affect the quality of life associated with health. However, if we evaluate trends, then the highest of the reduced correlation coefficients is of some interest. It’s about role physical functioning. The correlation coefficients of the melatonin index and the scales of the FPI questionnaire looked as follows: all significant correlation coefficients had a negative sign, that is, the personality properties corresponding to these coefficients were associated with a low concentration of melatonin. The ordering of the FPI scales by decreasing the significance of the correlation coefficients helped to identify the personal profile of hypomelatoninemia in the examined women. First of all, it was characterized by high levels of depressiveness and emotional lability.Conclusions. In the psychopathological structure of the personality of women of late reproductive and pre-menopausal age with endometrial pathology burdened with hypomelatoninemia, depressive and emotional lability is predominate. Reducing the secretion of melatonin is also associated with increased spontaneous aggressiveness, neuroticism and irritability.
Management of large chronic venous leg ulcers with negative pressure wound therapy
Authors: Walczak Dominik Andrzej , Wojtyniak Michał , Jaguścik Rajmund , Porzeżyńska Joanna Jadwiga , Fałek Wojciech , Czerwińska Monika , Ptasińska Karolina , Kozaczek Leokadia , Szymański Bartosz , Trzeciak Piotr Wojciech
Published: December 2017

Introduction: Venous leg ulcers (VLU) occur in 1\% of the adult population and are associated with chronic disability, diminished quality of life and high health-care costs. Treatment is often slow, difficult and recurrence is high because of inappropriate conditions of the wound bed.
Patients and Methods: This study involves 14 patients with chronic venous ulcers larger than 100 cm\textsuperscript{2} treated with negative pressure wound therapy (NPWT). Patients underwent a radical debridement of all devitalized tissues and partial stripping of an insufficient great saphenous vein in the first operation. After adequate haemostasis, NPWT kit was applied. Once the wounds were determined to be clean and adequate granulation tissue formation was achieved, split-thickness skin grafts were applied. Dressing impregnated with neutral triglycerides and silver ions was used as a first layer and the black polyurethane NPWT foam was applied over it. The pain assessment was performed for 7 patients using 10 cm visual analog scale (VAS).
Results: The mean number of NPWT dressing changes prior to grafting was 5.8. The mean number of NPWT foam changes was 2.8 after skin grafting. We accomplished complete healing of 92\% of applied skin grafts surface. One patient had recurrence of venous ulcers in the follow-up period. Moreover, one patient required regrafting.
Conclusions: The application of NPWT provides quick wound-bed preparation and high graft take in venous ulcer treatment.
Negative pressure wound therapy versus healing by secondary intention in pressure ulcers
Authors: Cirocchi Roberto , Georgi Popivanov , Mutafchiyski Ventsislav M , Boccolini Andrea , Randolph Justus , Massimo Lancia , Carlini Luigi
Published: December 2017

Pressure ulcers are a highly prevalent source of morbidity with an equally high incidence of up to 38.0\% amongst different categories of healthcare institutions. Therefore, the management and therapeutic approach toward these often hospital- or facility-acquired problems remain critical aspects of long-term care. Negative pressure wound therapy (NPWT) has proven effective in addressing the barriers to pressure ulcer healing including increasing blood flow to previously ischemic wound areas by generating subatmospheric pressure which vacuums in circulation. The objective of this study was to compare negative pressure wound therapy (NPWT) versus surgical wounds healing by secondary intention (SWHSI). A systematic literature search was conducted using the PubMed and Scopus search engine up until the 20 Th January 2017 including the terms: “negative pressure wound therapy” and “pressure ulcers”. In this systematic review, six randomized controlled trials were included. NPWT is deemed appropriate and effective method and widely used by clinicians to promote the healing of wounds and ulcers of different etiology.  The heterogeneity found in individual trials regarding the inclusion criteria, therapeutic procedures, the criteria and methods of outcome evaluation, however, did not allow for a data evaluation with statistically valid conclusions. It is reasonable to assume that their subset of patients with pressure ulcers that can be effectively treated with NPWT, with optimal results and good cost-benefit ratio, also with respect to the quality of life.
AVALIAÇÃO DO EFEITO DA ADIÇÃO DE SUBPRODUTO DE UMA INDÚSTRIA SIDERÚRGICA AO CONCRETO
Authors: Queiroz Inácio Santiago De Oliveira , Ruas Filho Nelton Figueiredo , Finelli Leonardo Augusto Couto , Ludvig Peter
Published: December 2017

Os concretos tradicionais estão evoluindo tecnologicamente, fruto da pesquisa aplicada e resultado da introdução conjunta, no elenco das matérias primas básicas do concreto, de adições minerais e aditivos químicos, proporcionando Concreto de Alta Resistência (CAR) e Concreto de Alto Desempenho (CAD). A sílica ativa, um dos materiais cimentícios suplementares mais utilizados na confecção do CAR e do CAD, é um subproduto da fabricação de silício metálico, das ligas de ferrosilício e de outras ligas de silício. Este presente trabalho apresenta caracterização do subproduto (sílica ativa) em relação à sua morfologia, análise química qualitativa, resultados para determinar a influência no comportamento deste material como adição mineral na propriedade mecânica de resistência à compressão axial, trabalhabilidade e acabamento no concreto, a fim de tornar a indústria da construção em concreto mais sustentável. Trata-se de um estudo experimental, exploratório, descritivo e análise quantitativa. A população é composta por corpos de prova de concreto moldados a partir dos materiais convencionais somados a adição da sílica ativa reaproveitada da indústria siderúrgica. A amostra é constituída por 50 corpos de prova de concreto moldados em laboratório, com 2 (duas) formulações, uma com adição de 5% de sílica ativa em peso de cimento e outra sem adição de sílica ativa, sendo a referência de traço empírico comumente utilizado na região de Montes Claros-MG para o fck de 25 MPa. Os resultados apontam a melhoria do acabamento dos corpos de prova, aumento significativo da resistência à compressão axial e relativa diminuição na trabalhabilidade.
INFLUÊNCIA DA UMIDADE E TEMPERATURA AMBIENTE NO PROCESSO DE SOPRO DO POLI (TEREFTALATO DE ETILENO)
Authors: Cruz Leandro Willian Mendonça , Da Silva Gilmar Cordeiro , De Almeida Tarcísio José
Published: December 2017

O Poli (Tereftalato de Etileno), mais conhecido pela sigla PET, é um dos polímeros de engenharia mais utilizado na produção embalagens, principalmente de frascos. A produção de garrafas de refrigerante, por exemplo, consiste em dois processos: injeção e sopro. É notável que o processo de injeção de PET seja afetado pela umidade ambiente, pois diversas injetoras possuem um secador no próprio silo de alimentação do equipamento. Desta forma, buscou-se avaliar se as condições ambientes também exerciam alguma influência no processo de sopro do PET. A análise foi realizada de forma amostral em dias diferentes, com condições ambientes diferentes e dentro da empresa Brasiaço Indústria e Comércio Ltda. Foi observado que apenas uma das condições ambientes afeta o processo de sopro de PET. Portanto, foi desenvolvido e proposto um método para correlacionar tal condição ambiente aos parâmetros do processo de sopro.
INVESTIGAÇÃO DA INFLUÊNCIA DA DOPAGEM DE CONDUTORES PROTÔNICOS DE CERATO DE BÁRIO
Authors: Nascimento Haruan Barreto Braga Capela do , Godinho Mario Junior , Kiminami Ruth Herta Goldschmidt Aliaga
Published: December 2017

Com a crescente demanda para sistemas de energia eficientes e ambientalmente amigáveis, a conversão direta de combustíveis gasosos em eletricidade por células combustíveis recebeu tremenda atenção nas últimas décadas. Sendo assim, o estudo da síntese e sinterização do cerato de bário, um dos materiais mais promissores entre as células combustíveis, é de suma importância para aperfeiçoá-lo ao se obter novos pós e microestruturas diferenciadas, tornando essas células economicamente viáveis.  A síntese pelo método de precursores poliméricos foi utilizada para o estudo da influência da dopagem do BaCeO3 com Y3+ como substituição parcial ao íon Ce4+. Os pós sintetizados foram caracterizados por análise térmica diferencial, difratometria de raios X, microscopia eletrônica de varredura,  e por BET. Os resultados mostraram que foi possível obter BaCeO3 dopadas com Y3+ , que o método de síntese favoreceu na formação da fase a 900 °C/2h e que o efeito da dopagem com o Y3+ no cerato de bário (BaCeO3) favoreceu na redução do tamanho médio das partículas  de 182 nm (sem dopante) para 94 nm (com o 20% Y3+ ).
Gestão de níveis de serviços: um instrumento para aprimorar as contratações da administração pública estadual e municipal
Authors: Schmitt Paulo Silvestre , Bier Clerilei Aparecida
Published: December 2017

A fiscalização de contratos administrativos, apesar da sua importância nas contratações públicas, é uma atividade que o Estado frequentemente tem dificuldades em operacionalizar e garantir aderência à legislação. Neste estudo avaliou-se qualitativamente se a introdução de acordos de níveis de serviços nos contratos administrativos e o estabelecimento da gestão de níveis de serviços (GNS) nas instituições públicas estaduais e municipais minimizariam não conformidades em suas contratações. Para tanto, os pesquisadores realizaram uma revisão sistemática na teoria da GNS e a confrontaram com os achados de uma análise de conteúdo aplicada em jurisprudências e relatórios de auditorias feitos pelo TCE/SC no período de 2006 a 2014, alicerçada por sete categorias de análise inspiradas na Lei de Licitações (Lei n. 8.666/1993). Ficou demonstrado que, para as não conformidades enquadradas nas categorias de análise, há respostas na GNS com potenciais para aprimorar as contratações públicas, desde que a sua adoção considere as particularidades da administração pública brasileira.Palavras-chave: Acordo de nível de serviço. SLA. SLM. Administração pública. Contratos administrativos. Abstract The supervision of public contracts, despite its importance in public procurement, is an activity that the state often has difficulties in operationalizing and ensuring adherence to the legislation. This study examined qualitatively whether the introduction of service level agreements in public contracts and the establishment of service level management (SLM) in state and municipal institutions would minimize nonconformities in their hiring. Therefore, the researchers underwent a systematic review of the theory of SLM and then confronted it with the findings of the content analysis applied in court decisions and audit reports performed by the Santa Catarina State Audit Court from 2006 to 2014, supported by seven categories of analysis inspired by the Brazilian Bidding Law (n. 8.666/1993). It demonstrated that, for the non-conformities classified in the categories of analysis, compelling answers exist in SLM with potential to improve public administration contracting, as long as its adoption consider the particulars of the Brazilian public administration.Keywords: Service level agreement. SLA. Public administration. Contract management.
Capacitação no setor público: analisando o processo de uma IFES
Authors: Teixeira Filho Antônio Raimundo Cardoso , Almeida Denise Ribeiro de , Almeida Leonardo Ribeiro de , Almeida Susan Mary Vieira de
Published: December 2017

Um dos marcos legais da adoção de modelos gerenciais na gestão de pessoas da administração pública brasileira foi a política de desenvolvimento de pessoas por meio da capacitação, trazida com o Decreto n. 5.707/2006. Nesse contexto, neste trabalho tomou-se como objeto a Universidade Federal da Bahia, com o objetivo de descrever e analisar o processo de capacitação implementado à luz da PNDP, caracterizando o modelo utilizado pela Instituição para capacitar o corpo técnico-administrativo, bem como os indicadores resultantes dessas ações institucionais. Para tanto, foi realizada análise de documentos institucionais, como também da literatura sobre o tema, a fim de se reunirem os elementos necessários às análises que deram respostas à questão de pesquisa. Assim, foram utilizadas também as técnicas de observação ativa e entrevistas informais. Os principais achados dizem respeito à formalização do modelo de capacitação na UFBA, à descrição quantitativa de servidores atendidos e aos impactos nos indicadores institucionais. O trabalho tem limitações em face ao escopo de atores institucionais participantes da pesquisa, sugerindo-se novos estudos com as percepções de atores e IFES não contemplados no estudo.Palavras-chave: Gestão de pessoas no serviço público. Capacitação nas IFES. Política pública.
Concepções de polivalência e professor polivalente: uma análise historico‐legal
Authors: Cruz Shirleide Pereira da Silva , Ramos Nathália Barros , Silva Kátia Augusta C. Pinheiro Cordeiro da
Published: December 2017

As concepções de polivalência e professor polivalência são resultantes de um processo histórico relacionadas à visão de educação, escola, conhecimento e formação profissional. Assim, o texto descreve, a partir de alguns documentos oficiais educacionais, tal processo no período de 1970 até as reformas pós anos 1990. Percebe a noção de polivalência e professor polivalente associada a um sentido generalista e superficial de trato com os conteúdos curriculares denotando uma relação economicista de relação “custo‐benefício” sob a justificativa de se suprir o déficit de professores para atuarem na crescente população escolar com ensino obrigatório estendido no período militar. Após as reformas dos anos 90 os documentos dão indícios de uma lógica das competências tanto como conteúdo formativo profissional como modo de construção do conhecimento por parte dos sujeitos. Tais documentos referendam ainda uma noção de conhecimento baseada numa perspectiva de interdisciplinaridade um tanto frágil quando esta é transposta do contexto epistemológico para o contexto educacional e pedagógico o que fragiliza também, uma compreensão apolítica de competências aos processos de profissionalização docente reforçando uma lógica de responsabilização.
Bacterias patógenas multidrogoresistentes aisladas en estetoscopios de médicos en un hospital de nivel III
Authors: Oliva-Menacho José , Oliva-Candela José , Garcia-Hjarles Marco
Published: December 2017

Objetivos: Determinar el perfil de susceptibilidad de bacterias patógenas aisladas en estetoscopios usados por médicos de un hospital de nivel III en Lima, Perú. Material y métodos: Estudio observacional, descriptivo y transversal, realizado en el Hospital Nacional Arzobispo Loayza. Ciento veintitrés bacterias aisladas se guardaron congeladas a - 20 °C. Posteriormente se sembró en placas de agar TSA, manitol salado y se procedió a incubar 24 horas a 37 °C. Se preparó una suspensión ajustada a 0,5 McFarland de turbidez, se procedió a inocular en placas de agar Mueller - Hinton (disco difusión); se determinó concentración mínima inhibitoria (MIC) en algunos casos y se utilizó antibióticos según la CLSI (Clinical and Laboratory Standards Institute). Resultados: Todas las cepas de Staphylococcus spp. coagulasa negativa, presentaron sensibilidad a ERI, DA, CIP, NF, LZD, VAN (100%); tres bacterias dieron resistencia a PEN, OXA, FOX (2,8%). Las cinco cepas de Staphylococcus aureus aisladas, presentaron sensibilidad a GE, AK, NF, LZD (100%); sin embargo, una cepa de Staphylococcus aureus presentó resistencia a FOX, VAN (20%). Las dos cepas de Acinetobacter spp. presentaron sensibilidad a IMI, MER, COL (100%). De las cuatro cepas de Pseudomonas aeruginosa, dos presentaron resistencia a FEP, IMI, MER (50%). La cepa de Escherichia coli presentó resistencia a IMI, MER. Conclusiones: Se tipificaron cepas de Staphylococcus coagulasa negativa y Staphylococcus aureus con resistencia a meticilina y vancomicina; Pseudomonas aeruginosa con resistencia a carbapenemasas y enterobacterias resistentes a cefalosporinas.
¿Son los signos neurológicos blandos relevantes en la esquizofrenia? Una revisión de la evidencia actual.
Authors: Huarcaya-Victoria Jeff
Published: December 2017

La esquizofrenia es un trastorno que incluye múltiples signos y síntomas en diferentes áreas (positiva, negativa, afectiva, motora, cognitiva, entre otras). De ellas, la dimensión motora ha adquirido notable importancia durante las últimas décadas. En tal contexto, los llamados signos neurológicos blandos (NSS) son de especial interés como posible expresión endofenotípica de la esquizofrenia, debido a su alta prevalencia en pacientes con este trastorno, y en sus familiares de primer grado. Estas alteraciones neurológicas están asociadas con síntomas negativos y de desorganización conductual, así como con deterioro neurocognitivo y pobre rendimiento funcional. Además, los NSS permitirían diferenciar distintos subgrupos de pacientes esquizofrénicos, con requerimientos específicos en cuanto a tratamiento, seguimiento, rehabilitación social y neurocognitiva. Asimismo, en estudios de neuroimágenes se han puesto en evidencia una gran variedad de alteraciones estructurales y funcionales, relacionadas con la heterogeneidad de los NSS. El presente artículo es una revisión actualizada de la literatura respecto al tema, intentando presentar una visión general de los estudios más representativos.
Psicosis inducida por ayahuasca: reporte de un caso.
Authors: Neyra-Ontaneda Diego
Published: December 2017

La ayahuasca es una bebida alucinógena, producto de la decocción de las plantas Banisteriopsis caapi y Psychotria viridis y que cuenta con N,N-dimetiltriptamina y β-carbolinas, como sus compuestos principales. Aunque produce alteraciones somáticas, cognitivas y subjetivas agudas, a menudo intensas, casi no se han reportado efectos adversos luego de un cuadro de intoxicación con este agente. En este artículo se presenta el caso de un varón de 40 años, procedente de la Amazonía peruana, que siguió un curso psicótico tras una sesión ritual de consumo; el episodio psicótico se resolvió favorablemente con tratamiento específico. Aun cuando infrecuentes, estos episodios pueden llegar a ser muy severos y asociarse a conductas violentas. Los usuarios con antecedentes de psicosis, manía o abuso de sustancias psicoactivas parecen estar en mayor riesgo. La literatura en relación al riesgo de reacciones adversas (incluidas conductas psicóticas) debidas al uso de ayahuasca, es escasa y poco concluyente por lo que casos similares al descrito deben evaluarse cuidadosamente y difundirse de manera apropiada.
Relative Greenhouse Gas Abatement Cost Competitiveness of Biofuels in Germany
Authors: Millinger Markus , Meisel Kathleen , Budzinski Maik , Thrän Daniela
Published: December 2017

Transport biofuels derived from biogenic material are used for substituting fossil fuels, thereby abating greenhouse gas (GHG) emissions. Numerous competing conversion options exist to produce biofuels, with differing GHG emissions and costs. In this paper analysis and modelling of the long-term development of GHG abatement and relative GHG abatement cost competitiveness between crop-based biofuels in Germany is carried out. Presently dominant conventional biofuels and advanced liquid biofuels were found not to be competitive compared to the substantially higher yielding options available: sugar beet based ethanol for the short to medium term least-cost option and Substitute Natural Gas (SNG) for the medium to long term. The competitiveness of SNG was found to depend highly on the emissions development of the power mix. Silage maize based biomethane was found competitive on a land area basis, but not on an energetic basis. Due to land limitations as well as cost and GHG uncertainty, a stronger focus on the land use of crop-based biofuels should be laid in policy.
Immanenz: Ein Leben … Friedrich Nietzsche
Authors: Böhler Arno
Published: December 2017

Im ersten Teil verhandelt der Text Nietzsches These, dass transzendente Interpretationen des Lebens in einer verborgenen Aggression lebendiger Organismen gegen das Leben als solches basieren. Nietzsche war vermutlich der Erste, der davon ausging, dass „metaphysische Annahmen“ in einem falschen Bild des Denkens gründen, das nicht zufällig, sondern konstitutiv den Blick auf unsere Instinkttätigkeiten verdrängt, die in den Souterrains unserer Leiblichkeit am Werk sind.Um zu begreifen, was für Nietzsche im Problem „Transzendenz versus Immanenz“ auf dem Spiel steht, muss man daher sein neues Konzept des Körpers untersuchen. Körper werden von ihm nicht mehr als massive, an sich seiende Dinge gedacht, sondern als weltweit exponierte Entitäten, die einer Vielheit von Kräften ausgesetzt sind. Einerseits den Kräften, die in den Souterrains der Leiblichkeit mehr oder weniger unbewusst am Werk sind, andererseits den Kräften, die Körper in ihrem In-der-Welt-sein von außen her weltweit affizieren.Im zweiten Teil wird das Forschungsfestival Philosophy On Stage#4. Nietzsche et cetera (Tanzquartier Wien 2015) als Beispiel eines kunst-basierten Philosophierens analysiert, das der Philosophie ihre Leiblichkeit, Materialität und Sinnlichkeit zurückgibt, indem es den Akt des Philosophierens auf der Bühne ausstellt und damit leiblich exponiert. Eine philosophische Denkungsart, die für Nietzsche in Opposition zum klassisch asketischen Bild des Denkens steht und daher einer neuen Gattung von Künstlerphilosoph_innen bedarf, die bereit und willens sind, mit Nietzsches Zarathustra zu fordern: „bleibt der Erde treu“.
Immanenz lesen
Authors: Lagaay Alice , Granzer Susanne Valerie
Published: December 2017

Der folgende Text eröffnete die Konferenz „Immanenz in zeitgenössischer Kunst und Philosophie“, die im Mai 2016 in Wien stattfand. Es handelt sich dabei um einen Reader mit Schlüsselaussagen zur Immanenz von Gilles Deleuze, Baruch de Spinoza, Giorgio Agamben, Henri Bergson, Francois Laruelle, Antonin Artaud und Friedrich Nietzsche. Dieser Reader wurde von Arno Böhler und Elisabeth Schäfer zusammengestellt. Susanne Valerie Granzer (S.V.G.) verarbeitete den Inhalt zu einer Kollage und trug Fragmente der Texte zum Beginn der Konferenz vor. Sie wurde dabei gelegentlich von Alice Lagaay (A.L.) unterbrochen, deren Einwürfe dazu dienten, Verbindungslinien zwischen den dichten theoretischen Texten und dem immanenten performativen Kontext zu ziehen, innerhalb dessen sie vorgetragen und aufgenommen wurden – d. h. dem Kontext der Konferenz. Der folgende Text bietet das Vorgetragene sowie die leichtherzigen – durchaus aber auch ernst gemeinten – Kommentare so dar, wie sie zur Aufführung kamen. Die Leser sind eingeladen, sich die Lebendigkeit (live-ness) des Ereignisses vorzustellen und sie nachzuerleben (re-enact), wobei ihre eigenen Kommentare, Fragen und Überlegungen die Lektüre unterbrechen.
Gilbert Simondon’s ‘Transduction’ as Radical Immanence in Performance
Authors: De Assis Paulo
Published: December 2017

Transduction is Gilbert Simondon’s key concept for understanding processes of differentiation and of individuation in a number of fields, including scientific disciplines, social and human sciences, technological devices, and artistic domains. Originating from the sciences and crucially developed in its philosophical implications by Simondon, transduction refers to a dynamic operation by which energy is actualized, moving from one state to the next, in a process that individuates new materialities. This chapter appropriates this concept for musical practice, aiming at establishing a foundational conceptual layer for a broader research effort that crucially includes artistic practice—both composition and performance—as its starting and end points. After an introductory depiction of what transduction might mean for a music performer, this paper focuses on the presentation of different definitions of transduction, mainly stemming from Simondon himself, but including two further extensions: one to Deleuze’s concept of haecceity (and via Deleuze, to my own micro-haecceity), the other to Brian Massumi’s notion of corporeality. Keeping in mind the potential of these definitions for the making of music, this essay explores eight different, yet complementary ways of thinking transduction, which are presented in a growing scale of complexity from the incandescent light bulb (3.1.) to the intricacies of decision-making in living organisms (3.8.), passing by the question of time and temporality (3.2.), thermodynamics (3.3.), information theory (3.4.), a redesigned theory of haecceities (3.5.), Riemannian topology (3.6.), and corporeality (3.7.). All these topics are presented here in short, as opening gates to wider fields of inquiry, suggesting future avenues of research, rather than claiming to offer finished thought.
A szervezeti tanulás és az innováció összefüggései a magyar oktatási rendszer alrendszereiben
Authors: Horváth László
Published: December 2017

A tanulmány az OTKA által finanszírozott „A helyi innovációk keletkezése, terjedése és rendszerformáló hatása az oktatási ágazatban” című kutatás egyik empirikus vizsgálatát mutatja be. A 2016 őszén zajlott adatfelvétel során a magyar oktatási rendszer 4241 köznevelési intézménye, 513 felsőoktatási szervezeti egysége és 99 for- és non-profit alapon működő szervezete válaszolt rövid kérdőívünkre, melyben többek között az innovációs tevékenység, aktivitás és gyakorlat jellemzőiről, valamint a szervezeti tanulási folyamatokról is kérdeztük a kitöltő szervezeti egységek vezetőit. A tanulmány részletes leírást tartalmaz a kutatás során alkalmazott innovációs index és szervezeti tanulási kapacitás félig-megerősítő faktorelemzés segítségével történő létrehozásáról, illetve ezek összefüggéséről és az oktatás különböző alrendszereiben való megjelenésükről. Az innovativitás és a szervezeti tanulás leírására szolgáló mutatók jelen tanulmányban elkülönülő változókat alkotnak, melyek a korábbi elméleti és empirikus tanulmányokkal szemben nem mutatnak erős összefüggést, inkább két különböző folyamatot jelölnek, melyek együttes működtetése nehéz, azonban a szubjektív fejlődési mutató alapján a legkívánatosabb. Az eredményeket ennek fényében a kétkezesség-elmélet szemszögéből elemezzük.
STATUS GIZI, ASUPAN CAIRAN DAN KEBUGARAN JASMANI ATLET DI PERSATUAN BULUTANGKIS KABUPATEN KUDUS
Authors: Rachma Fitri , Zulaekah Siti
Published: December 2017

Achievement of badminton athlete performance is supported by excellent physical fitness, normal nutritional status and adequate fluid intake. The purpose of this study was to determine the relationship of nutritional status and fluid intake with physical fitness athletes in Badminton Association of Kudus Regency. This research is an observational research with cross sectional approach. The populations in the study were badminton athletes in Kudus Region who met the inclusion criteria. Samples used 33 samples from the total population of 85 samples. Analysis of the relationship of nutritional status and fluid intake with athlete's physical fitness using Pearson Product Moment test. Based on the test of the relationship of nutritional status with athlete physical fitness obtained p value = 0.386. Analysis of the relationship of fluid intake with athlete's physical fitness obtained p value = 0.450. This study can be concluded that there is no relationship of nutritional status and fluid intake with athlete's physical fitness.

 
PENGARUH PENAMBAHAN LABU KUNING (Cucurbita moschata) dan Ikan Gabus (Ophiocephalus striatus) TERHADAP MUTU ORAGNOLEPTIK, KADAR PROTEIN DAN VITAMIN A BISKUIT
Authors: Arza Putri Aulia , Asmira Sepni
Published: December 2017

Nutrition potential and availability of pumpkin and cork in Indonesia are abundant, so diversification of pumpkin and cork fish in biscuit making is expected to be a more nutritious food alternative. This study was an experimental study using a complete randomized design consisting of three treatments, one control and two replications. This study was conducted in January - June 2016. Observations were made on organoleptic characteristics and protein content of biscuits. The subjective observation result using organoleptic test showed that the level of panelist's preference for color and texture was on treatment A (control) without the addition of pumpkin and cork fish. As for the aroma and taste with the best result is on the treatment of C with the ratio of pumpkin and cork fish (20 g: 20 g). The highest protein content was found in D treatment with the addition of pumpkin and cork fish (30 g: 30 g). Based on the results of research conducted, the addition of yellow squash and cork fish affect the color of biscuits and protein content of biscuits.

 

 

 
A pós-graduação e a sustentabilidade do abastecimento de comunidades ribeirinhas na Amazônia por meio de água de chuva: da concepção à ação
Authors: Leal Veloso Nircele Silva , Costa Cristiane , Lopes Ronaldo , Vasconcellos Mário , Carlos Tony , Ramam Dênio
Published: December 2017

Apesar de a Amazônia ser rica em recursos hídricos, suapopulação tem dificuldade no acesso à água potável. O abastecimentode água nas ilhas de Belém (PA) é deficitário. Alternativas locais quegarantam o acesso à água em quantidade e qualidade adequadas sãograndes desafios. O objetivo deste artigo é apresentar uma experiênciaintegradora de dois programas de pós-graduação na implementaçãode alternativas de aproveitamento da água de chuva para fins potáveisa fim de contribuir com a sustentabilidade do abastecimento local. Acaracterização socioeconômica e o diagnóstico do abastecimentode água subsidiaram a implantação dos sistemas. Verificou-se asustentabilidade por meio da aceitabilidade e do acesso ao sistema,dos impactos financeiros e dos padrões qualitativos da água. Deforma geral, são modelos positivos de abastecimento de água parapopulações ribeirinhas da Amazônia.
The Clock Drawing Test: A Reasonable Instrument to Assess Probable Dementia in Primary Care?
Authors: Reiner Katinka , Eichler Tilly , Hertel Johannes , Hoffmann Wolfgang , Thyrian Jochen Rene
Published: December 2017

Objective: The primary aim of the study was to determine accuracy, sensitivity and specificity
of the Clock Drawing Test (CDT) in detecting probable dementia as compared to the multi-domain
dementia screening test DemTect.

Methods:

The sample was derived from the general practitioner (GP)-based, cluster-randomized controlled
intervention trial DelpHi-MV (Dementia: life- and person-centered help in Mecklenburg-Western
Pomerania). Selected from 6.440 patients systematically screened for dementia in primary care, we examined
three groups (a,b,c) where the CDT (as index test) as well as the DemTect (as reference standard)
were available. After excluding cases with missing values, we included a sample of n=462 with
“probable dementia”, n=586 with “mild cognitive impairment” and n=553 with “no cognitive impairment”
matched for age and gender. We analyzed the accuracy of the CDT in identifying people with
probable dementia by the DemTect and report sensitivity, and specificity for the CDT. We further analyzed
age and gender differences associated with the groups.

Results:

In comparison to the DemTect the CDT identified more than twice as many of the screened
patients as cognitively impaired (63.1% in the CDT vs. 28.9% in the DemTect). The sensitivity and
specificity for the CDT were 84.4% and 45.6% respectively. We found considerable age and gender differences
for the performance of the CDT. Higher age (p < 0.001) and female sex (p < 0.001) were associated
with incorrect clock drawings.

Conclusion:

The CDT shows a considerably high rate of false positive screening outcomes compared to
the DemTect and disadvantages older people and women. Thus, in contrary to previous findings our results
indicate that the CDT should not be used as exclusive instrument to screen for probable dementia
in primary care.