bluuebunny/crossref_metadata_2025 huggingface dataset:
An Accident Detection and Classification System Using Internet of Things and Machine Learning towards Smart City
Authors: Balfaqih Mohammed , Alharbi Soltan Abed , Alzain Moutaz , Alqurashi Faisal , Almilad Saif
Published: December 2021

Daily traffic accidents increase annually, causing a significant number of death and disability cases. Most of fatalities occur because of the late response to these emergency cases. The time after the traumatic injury is called the golden hour, where providing essential medical and surgical aid at that time increases the probability of saving human lives by one-third an average. Thus, the focus of this paper was to develop a system based on IoT for accident detection and classification. The system detects and classifies vehicle accidents based on severity level and reports the essential information about the accident to emergency services providers. The system consists of a microcontroller, GPS, and a group of sensors to determine different physical parameters related to vehicle motion. In addition, different types of machine learning classifiers were examined with the developed system to determine the most accurate classifier for the system. The classifiers are the Gaussian Mixture Model (GMM), Naive-Bayes Tree (NB), Decision Tree (DT), and Classification and Regression Trees (CART). The implementation of the system showed that GMM and CART models were better in terms of precision and recall. It was also shown that the severity of accidents depends mainly on the g-force value and fire occurrence.
Factors Influencing Intention to Use Mobility as a Service: Case Study of Gyeonggi Province, Korea
Authors: Ko Eunjeong , Kwon Yeongmin , Son Woongbee , Kim Junghwa , Kim Hyungjoo
Published: December 2021

Mobility as a service (MaaS) integrates various transportation modalities and connects these modalities to enable users to travel from departure points to destination points. The objectives of this study were to analyze the factors influencing the intention to use MaaS and determine a direction for the implementation of this service. Hence, this study utilized an ordered probit model and marginal effect analysis. Specifically, a survey was conducted based on citizens living in Gyeonggi-do, South Korea, to prepare logical MaaS operation measures customized in this province. Subsequently, variables related to MaaS were classified, and statistical analysis was performed based on these variables. The need for integrated transportation service, intention to use shared mobility, gender, household income, and region are found to have significant effects. Moreover, demographic groups with high levels of intention to use MaaS were identified. Finally, the intention to use MaaS was found to be mainly affected by whether public transportation was the primary means of transportation or whether the subjects spent a comparatively long time commuting. It is expected that these findings will serve as the basis for MaaS implementation in the future and will also be used as fundamental data for transportation service planning.
Fabrication of Au-Nanoparticle-Decorated Cu Mesh/Cu(OH)2@HKUST-1 Nanorod Arrays and Their Applications in Surface-Enhanced Raman Scattering
Authors: Huang Xiaoqiao , Cai Li , Fan Tingting , Sun Kexi , Yao Le , Zhang Lijun , Li Zhongbo
Published: December 2021

Here we report a simple fabrication method for large-scale hybrid surface-enhanced Raman scattering (SERS) active substrates composed of Au-nanoparticle-decorated three-dimensional (3D) Cu(OH)2@HKUST-1 (Cu3(btc)2, H3btc = 1,3,5-benzenetricarboxylic acid) nanorod arrays on a woven Cu mesh (Cu mesh/Cu(OH)2@HKUST-1@Au). Cu(OH)2 nanorods were first obtained from a simple in situ chemical engraving Cu mesh and then utilized as self-sacrificing templates to achieve HKUST-1 nanocube-assembled nanorods; finally, Au nanoparticles (Au NPs) were sputtered onto the Cu(OH)2@HKUST-1 nanorods. Due to the large surface area, the three-dimensional Cu mesh/Cu(OH)2@HKUST-1 nanorods could load high-density Au NPs and capture target detection molecules, which is beneficial to the formation of a strong electromagnetic field coupling between Au NPs, and provides abundant “hot spots” for a sensitive and uniform SERS effect. Using the Cu mesh/Cu(OH)2@HKUST-1@Au nanorod arrays as the SERS substrate, 10−9 M Rhodamine 6G and 10−8 M 4-aminothiophenolcan were identified. To verify their practical application, the fabricated arrays were employed as SERS substrates for the detection of thiram, and 10−8 M thiram could be recognized. The hybrid SERS substrates show potential applications in the field of environmental pollutant detection and this is of great significance to the sustainable development of the environment.
The Low Frequency Perspective on Fast Radio Bursts
Authors: Pilia Maura
Published: December 2021

Fast radio bursts (FRBs) represent one of the most exciting astrophysical discoveries of the recent past. The study of their low-frequency emission, which was only effectively picked up about ten years after their discovery, has helped shape the field thanks to some of the most important detections to date. Observations between 400 and 800 MHz, carried out by the CHIME/FRB telescope, in particular, have led to the detection of ∼500 FRBs in little more than 1 year and, among them, ∼20 repeating sources. Detections at low frequencies have uncovered a nearby population that we can study in detail via continuous monitoring and targeted campaigns. The latest, most important discoveries include: periodicity, both at the days level in repeaters and at the millisecond level in apparently non-repeating sources; the detection of an FRB-like burst from a galactic magnetar; and the localisation of an FRB inside a globular cluster in a nearby galaxy. The systematic study of the population at low frequencies is important for the characterisation of the environment surrounding the FRBs and, at a global level, to understand the environment of the local universe. This review is intended to give an overview of the efforts leading to the current rich variety of low-frequency studies and to put into a common context the results achieved in order to trace a possible roadmap for future progress in the field.
Antiviral Strategies Using Natural Source-Derived Sulfated Polysaccharides in the Light of the COVID-19 Pandemic and Major Human Pathogenic Viruses
Authors: Ray Bimalendu , Ali Imran , Jana Subrata , Mukherjee Shuvam , Pal Saikat , Ray Sayani , Schütz Martin , Marschall Manfred
Published: December 2021

Only a mere fraction of the huge variety of human pathogenic viruses can be targeted by the currently available spectrum of antiviral drugs. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak has highlighted the urgent need for molecules that can be deployed quickly to treat novel, developing or re-emerging viral infections. Sulfated polysaccharides are found on the surfaces of both the susceptible host cells and the majority of human viruses, and thus can play an important role during viral infection. Such polysaccharides widely occurring in natural sources, specifically those converted into sulfated varieties, have already proved to possess a high level and sometimes also broad-spectrum antiviral activity. This antiviral potency can be determined through multifold molecular pathways, which in many cases have low profiles of cytotoxicity. Consequently, several new polysaccharide-derived drugs are currently being investigated in clinical settings. We reviewed the present status of research on sulfated polysaccharide-based antiviral agents, their structural characteristics, structure–activity relationships, and the potential of clinical application. Furthermore, the molecular mechanisms of sulfated polysaccharides involved in viral infection or in antiviral activity, respectively, are discussed, together with a focus on the emerging methodology contributing to polysaccharide-based drug development.
A Structural Perspective of Reps from CRESS-DNA Viruses and Their Bacterial Plasmid Homologues
Authors: Tarasova Elvira , Khayat Reza
Published: December 2021

Rolling circle replication (RCR) is ubiquitously used by cellular and viral systems for genome and plasmid replication. While the molecular mechanism of RCR has been described, the structural mechanism is desperately lacking. Circular-rep encoded single stranded DNA (CRESS-DNA) viruses employ a viral encoded replicase (Rep) to initiate RCR. The recently identified prokaryotic homologues of Reps may also be responsible for initiating RCR. Reps are composed of an endonuclease, oligomerization, and ATPase domain. Recent structural studies have provided structures for all these domains such that an overall mechanism of RCR initiation can begin to be synthesized. However, structures of Rep in complex with its various DNA substrates and/or ligands are lacking. Here we provide a 3D bioinformatic review of the current structural information available for Reps. We combine an excess of 1590 sequences with experimental and predicted structural data from 22 CRESS-DNA groups to identify similarities and differences between Reps that lead to potentially important functional sites. Experimental studies of these sites may shed light on how Reps execute their functions. Furthermore, we identify Rep-substrate or Rep-ligand structures that are urgently needed to better understand the structural mechanism of RCR.
COVID-19: Multiorgan Dissemination of SARS-CoV-2 Is Driven by Pulmonary Factors
Authors: Odilov Akmaljon , Volkov Alexey , Abdullaev Adhamjon , Gasanova Tatiana , Lipina Tatiana , Babichenko Igor
Published: December 2021

Multi-organ failure is one of the common causes of fatal outcome in COVID-19 patients. However, the pathogenetic association of the SARS-CoV-2 viral load (VL) level with fatal dysfunctions of the lungs, liver, kidneys, heart, spleen and brain, as well as with the risk of death in COVID-19 patients remains poorly understood. SARS-CoV-2 VL in the lungs, heart, liver, kidneys, brain, spleen and lymph nodes have been measured by RT qPCR using the following formula: NSARS-CoV−2/NABL1 × 100. Dissemination of SARS-CoV-2 in 30.5% of cases was mono-organ, and in 63.9% of cases, it was multi-organ. The average SARS-CoV-2 VL in the exudative phase of diffuse alveolar damage (DAD) was 60 times higher than in the proliferative phase. The SARS-CoV-2 VL in the lungs ranged from 0 to 250,281 copies. The “pulmonary factors” of SARS-CoV-2 multi-organ dissemination are the high level of SARS-CoV-2 VL (≥4909) and the exudative phase of DAD. The frequency of SARS-CoV-2 dissemination to lymph nodes was 86.9%, heart–56.5%, spleen–52.2%, liver–47.8%, kidney–26%, and brain–13%. We found no link between the SARS-CoV-2 VL level in the liver, kidneys, and heart and the serum level of CPK, LDH, ALP, ALT, AST and Cr of COVID-19 patients. Isolated detection of SARS-CoV-2 RNA in the myocardium of COVID-19 patients who died from heart failure is possible. The pathogenesis of COVID-19-associated multi-organ failure requires further research in a larger cohort of patients.
SARS-CoV-2 Post Vaccinated Adverse Effects and Efficacy in the Egyptian Population
Authors: Elgendy Marwa O. , El-Gendy Ahmed O. , Alzarea Abdulaziz Ibrahim , Mahmoud Sarah , Alqahtani Saad S. , Fahmy Alzhraa M. , El-Seedi Hesham R. , Sayed Ahmed M. , Alatawi Ahmed D. , Abdelrahim Mohamed E. A. , Alanazi Abdullah S.
Published: December 2021

Vaccines are the solution to overcome SARS-CoV-2. This study aimed to determine the post-Sinopharm vaccine safety-profile and immunity through antibody titers. Data were collected using a structured questionnaire from Egyptian participants who received two doses of Sinopharm vaccine. Data were divided into three parts, the first and second parts were to detect participants’ post-first and second dose symptoms and practices, and the third for the results of IgG anti spike protein antibodies test and laboratory tests. Pain, redness, swelling at the injection site, headache, fatigue, and lethargy were the most common post-vaccine symptoms for both first and second doses. Most of the participants felt mild or no symptoms after vaccination. The symptoms started mostly during the first day post-vaccination and lasted for no more than two days. Forty-nine percent of the participants resulted in positive antibodies tests on day 18 post-vaccination. The average antibody level for vaccinated participants with past SARS-CoV-2 infection was much higher than that for non-past infected participants. These vaccines’ administration methods need to be reevaluated by changing the dose, dose interval, adding a third dose, or mixing it with other vaccines with different techniques to improve their protection rates. Further studies are required to validate this finding.
Effectiveness of COVID-19 Vaccines against Delta (B.1.617.2) Variant: A Systematic Review and Meta-Analysis of Clinical Studies
Authors: Pormohammad Ali , Zarei Mohammad , Ghorbani Saied , Mohammadi Mehdi , Aghayari Sheikh Neshin Saeideh , Khatami Alireza , Turner Diana L. , Djalalinia Shirin , Mousavi Seied Asadollah , Mardani-Fard Heydar Ali , Kasaeian Amir , Turner Raymond J.
Published: December 2021

The high transmissibility, mortality, and morbidity rate of the SARS-CoV-2 Delta (B.1.617.2) variant have raised concerns regarding vaccine effectiveness (VE). To address this issue, all publications relevant to the effectiveness of vaccines against the Delta variant were searched in the Web of Science, Scopus, EMBASE, and Medline (via PubMed) databases up to 15 October 2021. A total of 15 studies (36 datasets) were included in the meta-analysis. After the first dose, the VE against the Delta variant for each vaccine was 0.567 (95% CI 0.520–0.613) for Pfizer-BioNTech, 0.72 (95% CI 0.589–0.822) for Moderna, 0.44 (95% CI 0.301–0.588) for AstraZeneca, and 0.138 (95% CI 0.076–0.237) for CoronaVac. Meta-analysis of 2,375,957 vaccinated cases showed that the Pfizer-BioNTech vaccine had the highest VE against the infection after the second dose, at 0.837 (95% CI 0.672–0.928), and third dose, at 0.972 (95% CI 0.96–0.978), as well as the highest VE for the prevention of severe infection or death, at 0.985 (95% CI 0.95–0.99), amongst all COVID-19 vaccines. The short-term effectiveness of vaccines, especially mRNA-based vaccines, for the prevention of the Delta variant infection, hospitalization, severe infection, and death is supported by this study. Limitations include a lack of long-term efficacy data, and under-reporting of COVID-19 infection cases in observational studies, which has the potential to falsely skew VE rates. Overall, this study supports the decisions by public health decision makers to promote the population vaccination rate to control the Delta variant infection and the emergence of further variants.
COVID-19 Vaccine Uptake among Younger Women in Rural Australia
Authors: Carter Jessica , Rutherford Shannon , Borkoles Erika
Published: December 2021

Vaccine uptake in younger Australian women living in rural and regional communities is poorly understood. This research explored factors affecting their decision making in the context of social determinants of health. A mixed methods design applying an explanatory sequential approach commenced with an online questionnaire followed by in-depth interviews with a sample of the same participants. The majority (56%) of participants indicated a positive intention to be vaccinated against COVID-19, but a substantially high proportion (44%) were uncertain or had no intention to be vaccinated. Significant factors affecting vaccine uptake included inadequate and sometimes misleading information leading to poor perceptions of vaccine safety. The personal benefits of vaccination—such as reduced social restrictions and increased mobility—were perceived more positively than health benefits. Additionally, access issues created a structural barrier affecting uptake among those with positive or uncertain vaccination intentions. Understanding factors affecting vaccine uptake allows for more targeted, equitable and effective vaccination campaigns, essential given the importance of widespread COVID-19 vaccination coverage for public health. The population insights emerging from the study hold lessons and relevance for rural and female populations globally.
Groundwater Recharge Assessment Using Multi Component Analysis: Case Study at the NW Edge of the Varaždin Alluvial Aquifer, Croatia
Authors: Karlović Igor , Marković Tamara , Vujnović Tatjana
Published: December 2021

Exploring the interaction between precipitation, surface water, and groundwater has been a key subject of many studies dealing with water quality management. The Varaždin aquifer is an example of an area where high nitrate content in groundwater raised public concern, so it is important to understand the aquifer recharge for proper management and preservation of groundwater quality. The NW part of the Varaždin aquifer has been selected for study area, as precipitation, Drava River, accumulation lake, and groundwater interact in this area. In this study, groundwater and surface water levels, water temperature, water isotopes (2H and 18O), and chloride (Cl−) were monitored in precipitation, surface water, and groundwater during the four-year period to estimate groundwater recharge. Head contour maps were constructed based on the groundwater and surface water levels. The results show that aquifer is recharged from both Drava River and accumulation lake for all hydrological conditions–low, mean, and high groundwater levels. The monitoring results of water temperature, chloride content, and stable water isotopes were used as tracers, i.e. as an input to the mixing model for estimation of the contribution ratio from each recharge source. The calculation of mixing proportions showed that surface water is a key mechanism of groundwater recharge in the study area, with a contribution ratio ranging from 55% to 100% depending on the proximity of the observation well to surface water.
What Is the Level of People’s Acceptance for Electric Taxis and Buses? Exploring Citizens’ Perceptions of Transportation Electrification to Pay Additional Fees
Authors: Clairand Jean-Michel , González-Rodríguez Mario
Published: December 2021

Electric vehicles (EVs) are gradually addressing the environmental problem in cities created by internal combustion vehicles. However, to be widely used, a major challenge will still have to be tackled. Some significant challenges are the resistance to new technologies and EVs’ purchase cost, which is significantly higher than that of internal combustion vehicles. These challenges are similar to the adoption of EVs for public transportation, such as buses and taxis. Thus, this paper proposes valuable insights into attitudes and preferences for taxi and bus users for the willingness to travel in EVs, by performing a convenience sampling, focusing especially on young users. Moreover, this study highlights the possibility of the users paying additional fees to travel in electric taxis (ETs) or electric buses (EBs). Pearson’s chi-squared analysis was also performed to validate the hypotheses.
Co-Simulation and Modeling of PMSM Based on Ansys Software and Simulink for EVs
Authors: Mersha Tewodros Kassa , Du Changqing
Published: December 2021

Electric vehicles (EVs) should have an electrical motor with high efficiency, high power density, and a wider constant power operating region, as well as ease of control and inexpensive manufacturing cost. To achieve these requirements, a real-time control-oriented electric motor model is essential. A co-simulation method based on Ansys software (Maxwell and Twin Builder) and MATLAB/Simulink for Permanent Magnet Synchronous Motor (PMSM) model is presented, which can improve the design of the PMSM and evaluate its performance by Rotating Machine Expert (RMxprt) when any slight modification of parameters and output inaccuracy occur. The PMSM drive system under different input reference speeds was analyzed by simulation, which testified that co-simulation of the magnetic and electrical domain is necessary to capture all applicable effects. The simulation results show the good feasibility of the motor model and control method, which achieves the desired effect and fast response with a small torque ripple as well. Such a developed prototype allows both accurate and simple characterization and optimization to be made possible.
Quiste aracnoideo y plasticidad cerebral: a propósito de un caso
Authors: Montalvo Herdoíza Juan Paúl , Vergara Ibarra Irene Monserrate , Macías Moreira Paula Salomé , Anzules Guerra Jazmín Beatriz
Published: December 2021

Se presenta un caso de quiste aracnoideo gigante paucisintomático, diagnosticado incidentalmente por Resonancia Magnética Nuclear (RMN) a los 5 años de edad, en el cual se evidenció una imagen hipodensa de gran tamaño ubicada en el lóbulo frontal derecho. El seguimiento, durante 17 años, no mostró ninguna alteración en las funciones cognitivas superiores dependientes del área afectada. Actualmente, la exploración neurológica del paciente es óptima. El paciente es un estudiante universitario brillante, lo que constituye un ejemplo contundente de plasticidad cerebral. Los quistes aracnoideos (QA) son tumoraciones benignas congénitas que forman una cavidad extracerebral, llena de líquido con características similares al líquido cefalorraquídeo (LCR), y recubierto por una membrana aracnoidea. La sintomatología por quistes aracnoideos dependen en gran manera del tamaño, y localización de la lesión. La clínica es variada incluyendo cefalea, deformidad craneana, déficit neurológico, convulsiones, entre otras manifestaciones, las cuales se presentan en más de la mitad de los casos. En ciertas lesiones intracraneales con efecto de masa se produce un fenómeno conocido como plasticidad cerebral que se define como la capacidad cerebral de evolucionar generando cambio estructurales y funcionales.

 

Palabras clave: plasticidad cerebral, quiste aracnoideo, resonancia magnética nuclear, neurología.

 

Abstract

 

This is a case of paucisymptomatic giant arachnoid cyst, incidentally diagnosed by Nuclear Magnetic Resonance (MRI) at 5 years of age, where a large hypodense image located in the right frontal lobe was evidenced, follow up for 17 years, did not show any alteration in the superior cognitive functions dependent on the affected area. Currently, the patient's neurological examination is optimal and he is a brilliant university student, which is a strong example of cerebral plasticity. The arcanoideos cysts (QA) are benign congenital tumors that form an ex-brain cavity, filled with liquid with characteristics similar to the cerebrospinal fluid (CSF), and covered by an arachnoid membrane. Symptoms due to arachnoid cysts depend greatly on the size, and localization of the lesion the clinic is varied including a headache, cranial deformity, neurological deficit, seizures, among other manifestations, which occur in more than half of the cases. In certain intracranial lesions with mass effect, a phenomenon known as cerebral plasticity is produced, is defined as the cerebral capacity to evolve, generating structural and functional changes.

 

Keywords: cerebral plasticity, arachnoid cyst, nuclear magnetic resonance, neurology.
Representaciones sociales del cáncer de mama en mujeres libres de enfermedad: Comparación entre México y Colombia
Authors: Chávez Díaz Alexis , Gómez González María Del Pilar
Published: December 2021

Con el objetivo de identificar las representaciones sociales sobre el cáncer de mama en mujeres libres de la enfermedad en México y Colombia, se llevó a cabo un estudio cualitativo basado en los métodos asociativos y de enfoque procesual y estructural de las representaciones sociales, en el que se incluyen 43 mujeres libres de enfermedad, ubicadas en Guadalajara, México y Pereira, Colombia. Se aplicaron listados libres y cuestionario de comparación de pares. Se realizó análisis de frecuencias, análisis de contenido temático y de índice de distancia para la construcción de las relaciones de términos de manera gráfica a través de los grafos. Para los dos grupos de mujeres, el Cáncer de Mama está asociado con aspectos negativos, en los que se destacan las palabras como miedo y muerte. Para las mujeres colombianas el aspecto físico, la estética y autoimagen tiene una gran relación. Las mujeres mexicanas destacan la importancia de la prevención como revisarse periódicamente. Se puede concluir que las representaciones sociales están directamente relacionadas con el marco contextual de estos dos grupos de mujeres, los antecedentes, los procesos de socialización y elementos propios de la cultura estructuran el significado y las acciones que toman asociadas a la salud y específicamente sobre el cáncer de mama.

 

Palabras clave: Cáncer de mama, conocimientos en cáncer de mama, representaciones sociales, salud pública.

 

Abstract

 

In order to identify the social representations of breast cancer in women free of the disease in Mexico and Colombia, a qualitative study was carried out based on associative methods and a processual and structural approach to social representations, in which It includes 43 women free of disease, located in Guadalajara, Mexico and Pereira, Colombia. Free lists and peer comparison questionnaire were applied. Frequency analysis, thematic content analysis, and the distance index were carried out to construct the relationship of terms graphically through the graphs. For both groups of women, Breast Cancer is associated with negative aspects, in which words such as fear and death stand out. For Colombian women, physical appearance, aesthetics, and self-image have a great relationship. Mexican women stress the importance of prevention as a regular check-up. It can be concluded that social representations are directly related to the contextual framework of these two groups of women, the antecedents, the processes of socialization and elements of the cultural structure the meaning and the actions they take associated with health and specifically about the breast cancer.

 

Key words: Breast cancer, knowledge, social representations, public health
Embarazo ectópico cervical: Reporte de caso clínico
Authors: Intriago Cedeño Carlos Fabricio , Murillo Mera Andrea Monserrate , Campoverde Mejia Nelson Efren
Published: December 2021

Los embarazos ectópicos constituyen la emergencia más peligrosa de la gestación en sus primeras etapas. Las presentaciones cervicales comprenden una subcategoría del embarazo ectópico, de naturaleza sumamente infrecuente, con una incidencia del 0,1% de casos, la implantación ocurre en el cérvix en lugar del útero y al ser un sitio de proximidad con las arterias uterinas, la invasión del trofoblasto al cérvix lo convierte en un embarazo ectópico de alto riesgo de compromiso hemodinámico. Se describe el caso de una paciente de 40 años de edad que debuta con cuadro clínico caracterizado por dolor en hipogastrio y fosas iliacas derecha e izquierda, acompañado por amenorrea y sangrado transvaginal, se realizó ecografía transvaginal que muestra la cavidad uterina vacía y una implantación anómala en el cérvix. Se comprobaron los criterios ecográficos de Ushakov, se ratificó la importancia clínica y diagnóstica urgente en esta patología y se instauró el tratamiento conservador quirúrgico de carácter controversial mediante el legrado uterino.
 
Palabras clave: cérvix, implantación, extrauterino, hemorragia, Ushakov
 
Abstract
Ectopic pregnancies constitute the most dangerous gestation emergency in its early stages. The cervical presentations include a subcategory of ectopic pregnancy, of a very rare nature, with an incidence of 0.1% of cases, implantation occurs in the cervix instead of the uterus and being a site of proximity to the uterine arteries, the invasion of the trophoblast to the cervix makes it an ectopic pregnancy with a high risk of hemodynamic compromise. We describe the case of a 40 years old patient who debuts with a clinical characterized by pain in hypogastrium and right and left iliac fossae, accompanied by amenorrhea and transvaginal bleeding, transvaginal ultrasound was performed showing the empty uterine cavity and an abnormal implantation in the cervix. The ultrasound criteria of Ushakov were checked, the clinical importance and urgent diagnosis in this pathology were ratified, and conservative surgical treatment of controversial character was established through uterine curettage.
 
Keywords: cervix, implantation, extrauterine, hemorrhage, Ushakov
Apego temprano en la evolución fisiológica y psicológica madre-hijo
Authors: Bella Méndez Manuel Andrade , Andrey Ortiz Pedro Mora , Pérez María Alejandra , Juan Zambrano Frangher Salas
Published: December 2021

Los beneficios del apego temprano, diada madre e hijo al momento del nacimiento, se basan en una estrecha interrelación con incidencia sobre aspectos fisiológicos y psicológicos de ambos. El objetivo fue analizar los efectos del apego temprano en la evolución fisiológica y psicológica madre-hijo. El estudio fue aplicado, mixto, exploratorio y descriptivo, de diseño no experimental, de campo y transversal. El área de estudio fue el Ambulatorio Urbano Palo Gordo con un número de partos mensuales promedio de cuatro. También se aplicaron dos cuestionarios: Maternal Attachment Inventory (MAI) y Escala de Apego durante Estrés (ADS). Se evaluaron dos partos eutócicos, con recién nacidos masculino y femenino, con talla, peso, temperatura y Apgar normales. El contacto piel a piel fue inadecuado en ambos, con mejores tiempos el primero, lo que se reflejó en un exitoso proceso de lactancia materna exclusiva. El desarrollo psicomotor no presentó diferencias. Una de las diadas madre-hijo presentó un alto grado de vinculación afectiva y conductas relacionadas con un apego sano, mientras que la otra no.

 

Palabras clave: Apego temprano, evolución, madre, hijo.

 

Abstract

The benefits of early attachment, mother and child dyad at birth, are based on a close interrelation with incidence on physiological and psychological aspects of both. The objective was to analyze the effects of early attachment on the mother-child physiological and psychological evolution. The study was applied, mixed, exploratory and descriptive, with a non-experimental, field and cross-sectional design. The study area was the Palo Gordo Urban Outpatient Clinic with an average number of monthly deliveries of four. Two questionnaires were also applied: Maternal Attachment Inventory (MAI) and Attachment Scale during Stress (ADS). Two eutocic deliveries were evaluated, with male and female newborns, with normal height, weight, temperature and Apgar. Skin-to-skin contact was inadequate in both, with better times the first, which was reflected in a successful process of exclusive breastfeeding. Psychomotor development did not show differences. One of the mother-child dyads presented a high degree of bonding and behaviors related to healthy attachment, while the other did not.

 

Keywords: Early attachment, evolution, mother, son
Leucemia de células dendríticas. A propósito de un caso
Authors: Cedeño Alvarado Verny Danilo , Barzallo Santillán Mónica , Navarrete Sornoza Danilo A. , Salazar Rodríguez Sirced , Cabrera Paola
Published: December 2021

La leucemia de células dendríticas es una patología hematológica maligna rara, altamente agresiva, derivada de precursores de células dendríticas plasmocitoides. Se manifiesta con lesiones cutáneas e infiltración a médula ósea. Se presenta el caso clínico de un paciente masculino de 63 años de edad, quien presentó deterioro neurológico en contexto de uremia y leucocitosis con sospecha de leucemia aguda. Para la confirmación del diagnóstico requirió marcadores inmunológicos por citometría de flujo. Se identificó fenotipo compatible con leucemia/linfoma blástico de célula dendrítica plasmocitoide. Se inició un régimen de quimioterapia esquema 7+3, basado en citarabina 338 mg + 500 ml de NaCl 0,9 % en infusión intravenosa continua de 24 horas e Idarrubicina 20 mg + 250 ml de NaCl 0,9 % pasar IV en 2 horas. Recibió terapia de sustitución renal por 5 sesiones. El paciente pasó a estado crítico pese a tratamiento oncohematológico, presentó fallo multiorgánico y paro cardíaco. Se realizó reanimación cardiopulmonar avanzada de alta calidad, sin obtener retorno de la circulación espontánea y se declaró su fallecimiento. Se concluyó que esta neoplasia oncohematológica permite pocas expectativas de vida y los protocolos terapéuticos que mejoren la sobrevida son escasos.

Palabras clave: Leucemia aguda, células dendríticas plasmocitoides, quimioterapia, cáncer, citometría de flujo.
Detección de problemas visuales que pueden influir en la nueva modalidad de clases y trabajo virtuales
Authors: Alcívar López Stalin , Aray Cedeño Michelle , Hidalgo Toasa Yamileth , Mero Santana Blanca Rosa , Pinargote Chávez Jailene , Zambrano Roldán Melanie
Published: December 2021

El uso de computadoras ha aumentado considerablemente en los últimos años. Se estima que en un 60 % de los hogares hay una computadora. Un gran número de personas que frecuentemente utilizan esta tecnología llegan a presentar síntomas visuales. En la actualidad, debido al confinamiento debido a la pandemia del COVID-19, ha aumentado el uso de la computadora a través de las clases en línea y del trabajo virtual. En este sentido, el objetivo de esta investigación fue determinar la existencia de problemas visuales como consecuencia de la limitada contingencia que obliga a las personas a trabajar y estudiar desde casa. Se realizó una investigación de tipo transversal, observacional, analítica y de campo a través de una encuesta mediante la herramienta Google Forms. Estuvo dirigida a una población de 335 personas entre 15 y 60 años de edad, predominantemente de la provincia de Manabí. La encuesta fue validada por juicio de expertos y permitió determinar los síntomas que sufren estas personas como consecuencia del tiempo que pasan frente a una pantalla, ya sea por teletrabajo, clases virtuales o entretenimiento.

Palabras clave: Síndrome de fatiga visual, síndrome visual informático (SVI), salud visual, teletrabajo, COVID-19.
Aplicación de la impresión 3D en la salud visual y ocular
Authors: Valencia Ceballos Laura Sofía , Patiño Sánchez Vanesa , Ríos Gaviria Alexander
Published: December 2021

A lo largo de los años se ha escuchado hablar acerca de la salud y medicina en general, así como los logros que se han ido alcanzando en ella gracias a los avances de la tecnología. A la luz de lo anterior, se generó el objetivo de esta investigación, el cual fue realizar un proceso de vigilancia tecnológica de la aplicación de la bioimpresión en el área de salud a nivel mundial, a partir de ecuaciones de búsqueda, creando una revisión periódica en metabuscadores. Este proceso permite tener un abanico de información a escala global. Posteriormente, se analizaron los datos estadísticos y documentos de la base de datos para determinar conclusiones mediante un análisis mixto, dando como resultado la revisión de investigaciones publicadas en los diferentes países referentes a procesos de impresión y bioimpresión en 3D enfocados al área de la salud y cómo estos brindan soluciones para mejorar la calidad de vida de las personas. Se hizo una revisión generalizada; luego se revisaron resultados puntuales que se consideraron relevantes en el campo y a continuación se plantearon oportunidades de desarrollo para procesos de investigación.

Palabras clave: bioimpresión; biotinta; medicina, salud visual y ocular.
Reflujo gastroesofágico y enfermedades respiratorias obstructivas en menores de 5 años, Hospital Dr. Verdi Cevallos Balda, Ecuador
Authors: Mera Sabando Ana Julia , López Álvarez Eva Yulissa
Published: December 2021

El reflujo gastroesofágico es el paso del contenido gástrico al esófago. Las manifestaciones respiratorias asociadas al reflujo gastroesofágico son frecuentes y variadas. Los pacientes pediátricos sufren reflujo por muchas razones como la inmadurez del músculo del esfínter esofágico inferior, comer en una posición no adecuada y la sobrealimentación. El objetivo de esta investigación radicó en relacionar el reflujo gastroesofágico y enfermedades respiratorias obstructivas en niños menores de 5 años de edad en el Hospital Dr. Verdi Cevallos Balda (Portoviejo, Manabí, Ecuador). La información se obtuvo de 26 historias clínicas del área de hospitalización, servicio de Pediatría. Los resultados mostraron que el 50 % de las enfermedades respiratorias obstructivas presentadas por los pacientes eran sibilancias recurrentes; a su vez, estas complicaciones se compararon con los resultados de pH-metría, observando que fue 9,37 veces mayor la probabilidad de que los pacientes con pH no ácido presentaran como complicación, bronquitis. Se concluyó que estos pacientes presentaron trastornos de peso y existió relación entre las complicaciones y el tipo de reflujo, como ocurrió entre pacientes con pH no ácido y bronquitis.

Palabras clave: Reflujo gastroesofágico; enfermedades pulmonares obstructivas; reflujo ácido; reflujo no ácido.
Bocio multinodular tóxico (enfermedad de Plummer): reporte de un caso
Authors: Morales Marín Omar José , Rodriguez Zambrano Maria Del Carmen , Corredor Carrero Nelson Dario , Perez Pulido Maria Alejandra del Valle , Sanchez Indra Oriana
Published: December 2021

El bocio multinodular tóxico (BMNT) o enfermedad de Plummer, se define como un aumento de volumen crónico de la glándula tiroides asociado a hipertiroidismo en ausencia de enfermedad autoinmune o neoplasia. Existen factores de riesgo asociados como tabaquismo, sexo, edad y predisposición genética. En el presente trabajo se analiza el caso de un paciente masculino de 75 años de edad que presentó aumento de volumen en región cervical anterior izquierda, asociado a dolor de moderada intensidad, signos de flogosis y, concomitantemente, disfagia y pérdida de peso. Como antecedente importante refirió tabaquismo. Se realizó hematología completa, glicemia y perfil de hormonas tiroideas; se evidenciaron niveles aumentados de T4 con niveles normales de TSH y ausencia de anticuerpos TPO. Se realizó ecografía tiroidea de alta resolución, reportando un aumento difuso del tamaño de la glándula tiroides a predominio del lóbulo izquierdo en todos sus ejes, sin evidencia de ganglios linfáticos aumentados de tamaño. Se estableció diagnóstico de BMNT asociado a diabetes mellitus tipo II, instaurándose un tratamiento con metimazol y metformina combinado con sitagliptina. Posterior a 10 días se evidenció mejoría en el perfil tiroideo, glicemia y disminución del bocio. Es importante considerar la presentación clínica de esta enfermedad, la cual es poco frecuente y se relaciona con la clínica manifestada por el paciente, así como los beneficios de la terapia con drogas antitiroideas en los casos de BMNT en pacientes ancianos.
Palabras clave: Bocio; hipertiroidismo; tirotoxicosis; bocio multinodular tóxico; terapia antitiroidea.
INFLUENCE OF DIFFERENT DOSES OF TISSUE BIOSTIMULANT ON BIOCHEMICAL BLOOD INDICES OF YOUNG CATTLE
Authors: ПУШКАРЕВ И.А. , АФАНАСЬЕВА А.И. , КУРЕНИНОВА Т.В.
Published: December 2021

Изучено влияние введения разных доз тканевого биостимулятора на биохимические показатели сыворотки крови ремонтного молодняка крупного рогатого скота. Опыт проводился в Алтайском крае на 4 группах ремонтных телочек Приобского типа черно-пестрой породы по 10 голов в каждой. При подборе животных учитывались возраст (1 мес) и живая масса (51,3±1,48 кг). Продолжительность опыта составляла 14 дней. Животным контрольной группы подкожно однократно вводили физиологический раствор в дозе 3,0 мл на 1 голову, I опытной — тканевый биостимулятор в дозе 2,0 мл, II — 3,0 мл, III — 4,0 мл на 1 голову. Опытную партию тканевого биостимулятора изготовили из субпродуктов и боенских отходов пантовых оленей по запатентованной технологии. Материалом для приготовления препарата служили мезентеральные лимфоузлы и средостения, селезенка, печень, матки с плодами (2—3 мес), плацента, отобранные в асептических условиях во время убоя здоровых животных. Введение тканевого биостимулятора телочкам в разных дозах способствовало повышению некоторых исследуемых биохимических показателей сыворотки крови. Наиболее оптимальной дозой применения тканевого биостимулятора следует считать 3,0 мл/гол, что способствует повышению содержания общего белка в сыворотке крови на 1,4% (P≤0,05), глюкозы — на 22,6% (P≤0,05) и снижению содержания холестерина на 12,3% (P≤0,05).

The effect of the administration of different doses of the tissue biostimulant on the biochemical blood serum indices of replacement young cattle was studied. The experiment was carried out in the Altai Region in 4 groups of 10 Black-Pied replacement heifers of the Priobskiy type. When selecting the animals, their age (1 month) and live weight (51.3±1.48 kg) was taken into account. The experiment lasted 14 days. Saline solution was injected under the skin to the animals of the control group at a dose of 3.0 mL per 1 head; the tissue bio-stimulant was administered in the following doses: in the 1st trial group — 2.0 mL per head; the 2nd trial group 3.0 mL per head; the 3rd trial group — 4.0 mL per 1 head. The trial batch of the tissue bio-stimulant was made from velvet antler deer by-products and slaughterhouse offal by using the patent-protected technology. The tissue biostimulant was made from mesenteric lymph nodes and mediastinums, spleen, liver, uteri with 2—3 month old fetuses, and placentae collected under aseptic conditions from healthy animals at slaughter. The administration of the tissue bio-stimulant to heifers in different doses increased some of the studied biochemical blood serum indices. The tissue biostimulant dose of 3.0 mL per head should be considered the most optimal one; it increased the total protein content in blood serum by 1.4% (P≤0.05), glucose — by 22.6% (P≤0.05), and decreased cholesterol content by 12.3% (P≤0.05).
Nuevas perspectivas sobre el movimiento en la filosofía francesa: la reivindicación ontológica de M. Merleau- Ponty y G. Deleuze
Authors: Lucero Jorge Nicolás
Published: December 2021

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Duygusal Zekâ Geliştirme Eğitim Programının (DZGP) Öğrencilerin Duygusal Zekâlarına Etkisi
Authors: YILMAZ Ercan
Published: December 2021

Bu araştırmada özelliklere dayalı duygusal zekâ yaklaşımının gelişimine yönelik deneysel bir çalışma tasarlanmıştır. Araştırma kapsamında Duygusal Zekâ Geliştirme Eğitim Programı (DZGP) geliştirilmiştir. Araştırmada Duygusal Zekâ Geliştirme Eğitim Programı’nın (DZGP) ortaokul öğrencilerinin duygusal zekâ becerilerinin gelişimi üzerindeki etkililiğini ortaya koymak amaçlanmıştır. Bu araştırmada, nicel yöntemler kapsamında, deneysel desen türlerinden ön test-son test kontrol gruplu deneysel desen kullanılmıştır. Araştırmanın örneklemini; ortaokul 8. sınıfta öğrenim gören, deney ve kontrol grubunun her birinde 30 öğrenci olmak üzere toplamda 60 öğrenci oluşturmaktadır. Araştırmada deney ve kontrol grubundaki öğrencilerin duygusal zekâlarını ölçmek amacıyla Duygusal Zekâ Özelliği Ölçeği kullanılmıştır. Araştırma süreci, deneysel işlem öncesi, deneysel işlem ve deneysel işlem sonrası olmak üzere üç aşamadan oluşmaktadır. Deneysel işlem öncesi dönemde DZGP geliştirilmiştir. Deneysel işlem aşamasında toplam 8 hafta, 40 oturumda deney grubuna DZGP ile eğitim uygulaması gerçekleştirilmiştir. Deney grubunda, DZGP öğretim etkinlikleri uygulanmış, kontrol grubunda ise herhangi bir uygulama yapılmamıştır. Deneysel işlem sonrasında araştırma kapsamında analizler yapılmıştır. Araştırmada deney grubunun duygusal zekâ alt boyutları ve toplam duygusal zekâ puanlarının ön ve son test puan ortalamaları karşılaştırıldığında son test puanları lehine anlamlı farklılıklar olduğu bulgusuna ulaşılmıştır. Ayrıca, araştırmada deney ve kontrol grubundaki öğrencilerin son test duygusal zekâ puanları ve toplam duygusal zeka puanları ortalamaları incelendiğinde, deney grubunun lehine anlamlı bir fark olduğu tespit edilmiştir.
Photocatalytic removal of Malachite green dye from aqueous solutions by nano-composites containing titanium dioxide: A systematic review
Authors: Amiri-Hosseini Soheila , Hashempour Yalda
Published: December 2021

Background: Malachite green (MG) is widely used as a fungicide, Bactericide parasiticide in the aquaculture industry, as a food additive, medical disinfectant, and also, as a dye for materials such as silk, leather, paper, etc. In this study, the photocatalytic removal of MG from aqueous solutions using TiO2-containing nanocomposites was reviewed. Methods: In this study, four databases (PubMed, Web of Science, ScienceDirect, and Scopus) were systematically searched to collect studies on the decomposition of MG using nanocomposites containing TiO2 under UV light radiation. Results: In total, 10 related and eligible studies were selected. Based on the results, TiO2 was doped with iron, Sn, Ag, Si, and Ni. The highest percentage of photocatalytic decomposition for MG was observed in Sn > Ni > Ag > Fe > Si. The removal efficiency of MG in the studied papers was between 75%-100%. Conclusion: Recombinant nanocomposites had a higher dye removal percentage than uncombined ones because they play an important role in the photocatalytic process of dye, by producing free radicals.
Detection to trace aluminum ion of pharmaceutical wastewater using synthesis of Schiff-based chemosensor
Authors: Jemberu Dagnaw Mengistu , Gopal Mahesh
Published: December 2021

Background: The aim of this research was to develop a fluorogenic sensor for Al3+ions, which have been identified as a possible food and drinking water pollutant by the WHO and considered to be harmful to human health. Methods: The sensing mechanism was based on excited-state intramolecular proton transfer, with the intramolecular rotation restriction occurring after binding with the analyte. The probe attaches Al3+selectively and emits strong emission in 4:1 H2 O/MeOH (v/v) solution while irradiated at 400 nm in the presence of a wide number of cations, acting as a "turn-on" fluorescence chemosensor. The range of detection for Al3+is 3.3 nM (3 method), which is more than 200 times more responsive than the WHO suggested limit of 7.4 mM (3σ method). Mass spectra, job plot, and Benesi-Hildebrand plot were used to determine the formation of the 1:1 metal-to-ligand complex. Results: Aluminum (Al) ion content in effluent obtained from the pharmaceutical sector is 0.381 mM, which is a trace amount. A separate in vitro experiment indicates that the probe can precisely perceive Al3+ions in a cell line. The sensor-based method is developed to detect 3.3 nM of Al3+ions, which is significantly less than the WHO max. Conclusion: The probe to detect Al3+ions in live cells. HL becomes a flexible sensor for recognizing intracellular Al3+in human liver cancer cell line Hep G2 and human lung fibroblast cell lines by fluorescence cell imaging procedures, and the probe’s non-toxicity has been proven by MTT tests up to 100M.
INTERVENSI PRAKTIK PEMBUATAN PUPUK KOMPOS DENGAN BAHAN DASAR SAMPAH ORGANIK RUMAH TANGGA
Authors: Fitriani Tia , Amalia Icca Stella , Budiman Iding , Apriyanto Apip , Noviyanti Hany , Hilman Ridwan
Published: December 2021

Pendahuluan: Faktor yang menyebabkan permasalahan sampah di Indonesia karena meningkatnya taraf hidup masyarakat yang tidak disertai dengan keselarasan pengetahuan tentang persampahan dan juga partisipasi masyarakat yang kurang untuk memelihara kebersihan dan membuang sampah pada tempatnya. Tujuan: kegiatan ini untuk mengetahui alternatif solusi dari masalah perilaku pengelolaan sampah dalam konteks penanganan dengan sasaran ibu-ibu PKK di Desa Darma Kecamatan Darma Kabupaten Kuningan. Metode: ceramah dengan menggunakan media power point. Instrumen penilaian terhadap pengetahuan responden yaitu menggunakan lembar kuesioner sebelum pelatihan dan sesudah pelatihan serta lembar evaluasi sebagai penilaian kegiatan. Hasil: Hasil evaluasi kegiatan menunjukkani bahwa sebagian besar peserta memiliki nilai post test lebih besar dibandingkan dengan nilai pre test yaitu sebanyak 17 orang. Hal ini menunjukkan bahwa dengan diadakannya penyuluhan dapat meningkatkan pengetahuan peserta. Kesimpulan: Kegiatan intervensi pembuatan kompos ini memberikan dampak positif pada pengetahuan ibu-ibu PKK dalam pengolahan sampah organik dengan metode ceramah dan demonstrasi.