bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case of Primary Thyroid Maltoma
Authors: Jeong Suhwan , Park Gi Cheol
Published: June 2024

Mucosa-associated lymphoid tissue (MALT) lymphomas comprise 7.6% of non-Hodgkin’s lymphomas (NHLs) and they are recently recognized B-cell subset of NHLs. They are originated from gastrointestinal tract most frequently but may also occur in other organs including head and neck, lung, skin, thyroid and breast. Primary thyroid lymphomas (PTLs) constitute up to 5% of all thyroid malignancies. Diffuse large B-cell lymphoma is most common type of PTLs and MALT lymphoma is relatively rare subtype of PTLs. Thyroid MALToma arises in chronic inflammatory conditions with autoimmune or infectious etiologies. The optimal treatment regimen still remains controversial. However, It is reported that localized thyroid MALT lymphoma has excellent survival rate after surgical resection alone. We report a case of 48-years-old woman with primary thyroid MALToma.
El Cezeri’nin Minyatürlerinden 20. Yüzyıla Kadar Sibernetik Sanatın İncelenmesi
Authors: Bülbül Selda , Öztürk Gülşen
Published: June 2024

El Cezeri, minyatürlerinde kendi dönemi olan 13. yüzyıl sanat anlayışını, robot ve otomatları merkeze alan bir yaklaşımla sunar. 20. yüzyılda ise gelişen sanat anlayışının makineler, robotlar ve yeni teknolojilerle beslenen bir ortam yarattığı ve bu alanda eserler üretildiği görülmektedir. Bu çalışmada, 1960'lı yıllarda özellikle enstalasyon, heykel ve sahne sanatlarında başlayan sibernetik sanat anlayışının 800 yıl önce yaşamış olan ve bu biliminin öncüsü olarak kabul edilen El-Cezeri'nin robotik minyatürleri üzerindeki erken etkisi incelenerek betimlenmeye çalışılmıştır. Tasarladığı robotlar ve makineler üzerindeki sibernetik sanat etkilerinin ortaya konulması ve aynı zamanda sanatçı kimliğinin ön plana çıkarılması amaçlanmıştır. El Cezeri'nin interaktif ve mizansen makinelerinin, sibernetik sistemlerle yapılan sanat eserlerinin erken örnekleri olduğu görülmektedir. Çalışma, “Kitab-ül Hiyel” adlı eserden, ses, ışık, renk, hareket ve etkileşim özelliği içeren robotik konulu minyatürlerle birlikte 20. yüzyılda sibernetik sistemlerle yapılan sanat eserleri ile sınırlandırılmıştır. Literatür taraması yöntemi tercih edilmiş ve çalışmaya konu olabilecek eserler üzerinde karşılaştırmalar yapılmıştır.
Even one tardigrade is enough. Molecular methods revealed presence of pantropical species Echiniscus lineatus (Heterotardigrada, Echiniscidae) in the fauna of Seychelles
Authors: Tumanov Denis , Khabibulina Valeriia
Published: June 2024

A brief report on the tardigrade species Echiniscus lineatus discovered in a moss cushion collected in Seychelles is given. The species represents a new pantropical element in the tardigrade fauna of Seychelles. With this record the number of echiniscid tardigrade species in Seychelles has reached five. Morphological identification of the species is supported with the analysis of obtained sequences of nuclear and mitochondrial DNA barcode genes (ITS-1, ITS-2 and COI). Analysis of the genetic data using the method of TCS haplotype networks revealed separated position of the Seychellian population of E. lineatus and supported the hypothesis of independent colonisation of Seychelles.
Assessment of seasonal fluctuation in heavy metal contamination in sediments and surface water of Narmada River, India
Authors: Rahi Dal Chand , Chandak Rajeev , Vishwakarma Amit
Published: June 2024

This study aimed to assess the seasonal fluctuation of heavy metal contamination in the sediments and surface water of the Narmada River. In this context, samples were gathered from six stations along the river in 2021–2022 and their concentrations were determined by utilizing Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). The results in sediments, the average concentrations of As, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn were 0.05, 1.03, 2.47, 1.64, 750.17, 17.75, 0.54, 0.13, and 1.12 mg/kg and in water, the average concentrations of Co, Fe, Ni, and Zn were 0.03 μg/l, 0.01 mg/l, 0.08 μg/l, and 0.39 μg/l. Seasonal fluctuation in sediments revealed that concentration of metals As, Cu, Fe, Ni, and Zn peaked during the rainy climate, while Co and Cr peaked during the post-monsoon and Mn and Pb peaked during the summer climate. Seasonal fluctuation in water, Co, Ni, and Zn exhibits their highest concentrations during the post-monsoon. The finding of pollution indices revealed that the contamination level was low to moderate. Cluster analysis revealed anthropogenic and agricultural runoff water as a contributor to contamination. The findings of this research enhance comprehension of heavy metal contamination in sediment and water of the Narmada River.
Development of machine learning models for estimation of daily evaporation and mean temperature: a case study in New Delhi, India
Authors: Rajput Jitendra , Kushwaha Nand Lal , Srivastava Aman , Pande Chaitanya B. , Suna Triptimayee , Sena D. R. , Singh D. K. , Mishra A. K. , Sahoo P. K. , Elbeltagi Ahmed
Published: June 2024

Accurate prediction of pan evaporation and mean temperature is crucial for effective water resources management, influencing the hydrological cycle and impacting water availability. This study focused on New Delhi's semi-arid climate, data spanning 31 years (1990–2020) were used to predict these variables using advanced algorithms such as Bagging, Random Subspace (RSS), M5P, and REPTree. The models were rigorously evaluated using 10 performance metrics, including correlation coefficient, mean absolute error (MAE), and Nash–Sutcliffe Efficiency (NSE) model coefficient. The Bagging model emerged as the best model with performance indices values as r, MAE, RMSE, RAE, RRSE, MBE NSE, d, KGE, and MAPE as 0.86, 0.76, 1.43, 32.70, 49.44, 0.03, 0.85, 0.96, 0.90, and 22.0, respectively, during model testing phase for pan evaporation prediction. In predicting mean temperature, the Bagging model reported the best results with performance indices values as r, MAE, RMSE, RAE, RRSE, MBE NSE, d, KGE, and MAPE as 0.86, 0.76, 1.43, 32.70, 49.44, 0.03, 0.85, 0.96, 0.90 and 22.0, respectively, during the model testing phase. These findings offer valuable insights for enhancing relative humidity prediction models in diverse climatic conditions. The Bagging model's robust performance underscores its potential application in water resource management.
Agencia indígena y procesos de cambio: una perspectiva decolonial sobre las prácticas y creencias religiosas de las comunidades koguis de Muñkuawinmaku
Authors: Sabbato Arianna
Published: June 2024

Este documento retoma algunos de los pasajes centrales de una investigación previa llevada a cabo como tesis de maestría de la autora, entre las poblaciones koguis administradas por la Asociación de Autoridades Tradicionales Kogui del Magdalena Muñkuawinmaku. La investigación se desarrolla en el marco de un conflicto entre los líderes de estas poblaciones y los de la Organización Gonawindúa Tayrona. Esta segunda organización no reconoce la legitimidad del liderazgo de Muñkuawinmaku, al parecer porque está establecido con el apoyo de autoridades educadas en instituciones evangélicas. De este contexto desprende el debate acerca de la legitimidad de la gobernación de los territorios indígenas y la preservación de su identidad cultural. Mediante una metodología etnográfica, multi-situada y decolonial se investiga la agencia de las poblaciones bajo el mando de Muñkuawinmaku, mientras se cuestiona la “obsesión por la tradicionalidad” y su oposición ideológica a la reelaboración de prácticas indígenas que desembocan en la construcción de nuevas relaciones con las instituciones. Resulta fundamental que la epistemología decolonial tome en cuenta la complejidad y la especificidad del caso, y respete las perspectivas de los pueblos originarios en cuanto a la rearticulación de sus prácticas y creencias.
Palynostratigraphy and paleoenvironment of the South Rifian Ridges (Morocco) Upper Domerian-Lower Toarcian sequence: A transitional domain between the Proto-Atlantic and the Tethys
Authors: Chahidi Soumia , Hssaida Touria , Benzaggagh Mohamed , Oumalch Fatima , Jaydawi Soukaina
Published: June 2024

This paper relates to two marly outcrop sections of the South Rifian Ridges central unit (Moulay Idriss Zerhoun area), dated by Upper Domerian-Lower Toarcian ammonites. The Upper Domerian marls from the SKM outcrop section (Souk of Moulay Idriss Zerhoun) have yielded palynofacies very rich in lignitic particles (needle-like phytoclasts), Tasmanites (unicellular green algae), spores and pollen grains. The marine microfossils, especially dinoflagellate cysts and acritarchs, are not present. These latter marine organisms are predominant in the Lower Toarcian palynofacies samples collected from the FA (Feddane Amar) outcrop section, in association with a significant amount of lignitic particles. This striking difference in the palynological content between the palynofacies of the Upper Domerian and the Lower Toarcian indicates an important change in the marine paleoenvironment in the South Rifian Ridge domain. Therefore, the anoxic period during the Upper Domerian is marked by the abundance of spores and pollen grains and the absence of marine microfossils, except for the Tasmanites; it is followed by a normal salinity-marine period, characterized by abundant marine-related palynomorphs, in the Early Toarcian. This paleoenvironmental change may be related with the Middle Liassic carbonate platform dislocation of the South Rifian Ridge domain and probably to the global marine transgression, occurring at the base of Toarcian, known all over the world.
Tholeitic basalts and ophiolitic complexes of the Mesorif Zone (External Rif, Morocco) at the Jurassic-Cretaceous boundary and the importance of the Ouerrha Accident in the palaeogeographic and geodynamic evolution of the Rif Mountains
Authors: Benzaggagh Mohamed
Published: June 2024

The stratigraphical series around the Jurassic-Cretaceous boundary of the External Rif Mountains, in particular those in the Mesorif Zone, exhibits many outcrops with volcanic materials spread westwards over 200 km. These materials show diverse aspects: basalt lithoclasts reworked into calcareous breccia beds or in marly matrix breccia, interstratified lava flows and volcanoclastic complexes incorporated within the Berriasian marls. In the Central Rif, several magmatic blocks outcrop, usually regarded as granite scales from the Paleozoic basement or as intrusive gabbros of Barremian age. Actually these magmatic massifs display typical ophiolitic sequences and they are overlaid by mega-olistoliths of Jurassic materials and locally by radiolarite layers. Geochemical analysis of several basalt and gabbro samples belonging to the Mesorif Zone evidenced that both display a typical E-MORB magma indicating at least partial oceanization of the Mesorif basement. Concerning geodynamics, the Mesorif Zone had undergone, at the Jurassic-Cretaceous boundary interval, two successive palaeogeographic phases: an uplift, close to emersion during the Kimmeridgian-Early Tithonian interval, stressed by important submarine volcanic activities and intense brecciation of the carbonate formations, followed by a general collapse at the Late Tithonian, underlined by lava flows, slumping as mega-olistoliths and the formation of an oceanic crust, at least in the Central Rif. These magmatic materials, distributed on both sides of the Ouerrha Valley, evidence that this westwards extending valley (the Nekor Accident), may correspond in the Central Rif, to two palaeo-subduction planes which become two major overlapping thrusts in the western part of the Rif Mountains.
New insights on the Marseille-Aubagne Oligocene basins (France)
Authors: Nury D. , Villeneuve M. , Arlhac P. , Gärtner A. , Linnemann U. , Châteauneuf J. J. , Riveline J. , Hippolyte J. C.
Published: June 2024

The Marseille-Aubagne Basins, which extend from Marseille to Roquevaire, occupy more than fifty per cent of the Marseille-Aubagne geological map, with approximately one million people living in this area. Despite this geological importance they are still poorly known. The first synthetic view was delivered in the 1935 geological map. Studied by Bonifay, the Quaternary deposits have been included in the 1969 geological map. Nevertheless, the Oligocene formations remained unmodified until Nury, who provided a lot of very detailed stratigraphic data. New studies have been carried out in the frame of the third issue of the 1:50,000 geological map. These studies allow us to distinguish between three different basins: the “Jarret basin” in the northern part, the “Prado basin” in the southwestern part and the “Aubagne basin” in the eastern part. Each of them contains its own stratigraphic succession, including several formations from the Rupelian to the Chattian. Globally, the Lower to Upper Rupelian formations are tectonically deformed, whilst deposits from the Latest Rupelian to the Latest Chattian show only slight deformation. Thus, two main geodynamic stages have been distinguished: the first beginning with the Early Oligocene extensive regime leading to the opening of NNE-SSW troughs all over the European platform and, the second, beginning with a NNW-SSE extensive regime coeval with the Western Mediterranean rifting. The key point that separates these two stages from each other is a possible Late Rupelian compressive regime. To sum up, this basin can be considered as a natural archive for the Oligocene events. Therefore, these basins should be considered as masterpieces for the Oligocene palaeogeographic and geodynamic reconstructions.
Evidence for an intra-Oligocene compressive event in the Marseille-Aubagne basins
Authors: Villeneuve Michel , Nury Denise , Arlhac Pierre , Gärtner Andreas , Linnemann Ulf , Pantaine Loïc
Published: June 2024

An Oligocene tectonic event has been suspected as the origin of thrusts and folds in several Oligocene troughs and basins of Provence, including the Marseille-Aubagne basins. Deformations are generally assumed to be to a post Oligocene extensional event. The Marseille-Aubagne basins are geographically and stratigraphically separated into three basins (Jarret, Prado and Aubagne) with each of them exhibiting their own sedimentary succession. However, each of the successions includes two main units: - The lower unit which includes several formations attributed to the Rupelian age. All of these sediments are strongly or slightly deformed depending on their location with respect to the main faults. - The upper unit which includes formations of mainly Chattian age. They are undeformed or slightly deformed.
Geological sections across the southern Prado basin show a succession of anticlines and synclines. Additionally the thrusting of the Carpiagne massif over the Prado basin has been evidenced since 1952. These deformations are here related to a compressional event.
According to palaeontological data, the latest deformed strata are ascribed to the Late Rupelian, whereas the earliest undeformed strata are ascribed to the Latest Rupelian. This is in accordance with age determinations on detrital zircons extracted from the latest deformed sandstone, and from the youngest age of detrital zircons from the undeformed sandstone. Thus, the stratigraphic limit between the deformed and undeformed formations should be set around the Rupelian / Chattian limit (28.1 Ma) according to the latest chronostratigraphic chart. Finally, we discuss correlations with similar events occurring around the Mediterranean area.
The superposed orogenesis of the alpine-mediterranean edifice
Authors: Argyriadis Ion
Published: June 2024

The circum-Mediterranean chains must be considered as the result of two distinct orogenies. The apparent unity of the present structure is of formal order, due to the latest deformations. Since the Hercynian time there have been two periods of paroxysmal deformation; the younger fits the definition of the alpine orogeny; the older occurred during the Cretaceous and may correspond to the first great convergent relative drift of the Eurasiatic and African blocks. The Cretaceous or Mesogean orogeny is independent from the Alpine orogeny stricto sensu (Oligo-Miocene) and cannot be considered as its prefiguration. Being independent in time, it is independent in space as well. Even if this Mesogean orogeny can appear locally restricted to the ‘’internal’’ parts of the Alpine chains (Central Mediterranean area, Carpathes, Dinarides) this cannot be taken as a rule: towards the west, the Cretaceous deformations cross the axis of the western Alps and extend (new investigations) over Provence to the Betic chains and the Pyrenean area. Towards the east, the deformations of this period cross the Hellenides (new observations) and spread over the ‘’external’’ area in a spectacular way, interesting areas which have never been tectonised again (Cyprus, south-eastern Anatolia, northern Syria, Oman). As a whole, this large Cretaceous orogenic zone is part of a wider domain which extends over central Iran towards the Himalayas and eastern Asia, and has its equivalent on the western side of the Atlantic Ocean, in the Caribbean islands, Mexico and the Americas.
The “Société Géologique du Nord” (SGN) and Earth Sciences in Northern France
Authors: Blieck A. , Meilliez F.
Published: June 2024

The “Société Géologique du Nord”, located in Lille, in northern France, was founded in 1870, with Jules Gosselet as the first president. It has always been closely connected to the geology department of the Faculty of Sciences of Lille, now called the “Université de Lille – Sciences et Technologies”, and keeps strong links with the Natural History Museum of Lille. Its activities and evolution were closely related to those of the coal-mining basin of the area until the last shaft was closed in 1990. Its activities are both in the fields of applied and fundamental geosciences. From its beginning, the Society has published the results of the research of its members, both in a periodical journal, the Annales, and as monographies called Mémoires. From the 1970s, the Mémoires have been progressively replaced by Publications, mostly devoted to State doctoral theses. During the transition from the 20th to the 21st century, the activities of the Society have strongly declined, due to several internal and external factors. Since the beginning of the 21st century, the SGN has tried to adapt itself to the new conditions of both the university and the regional territory. It is still a scientific society, but it is open to its social environment.
A Comprehensive Overview of Recent Trends in the Production of Nitrogen-Containing Heterocyclic Compounds Using Nanocatalysts
Authors: Gaikwad Dhananjay N. , Gaikwad Suresh T. , Manjul Rajesh K. , Rajbhoj Anjali S. , Suryavanshi Dayanand M. , Varade Gaurav A. , Dhane Nilam S.
Published: June 2024

Nanocatalysis is the newest invention in the area of synthetic chemistry that has changed
the process of chemical transformation. The nanocatalysts have various benefits as compared to traditional
catalysts, such as simple and economical methods of synthesis, high surface-to-volume ratio,
large number of active sites, excellent selectivity, increased stability, rapid recovery, and recyclability.
In recent years, nanomaterials have been extensively employed in the production of heterocyclic
moieties. This study intends to emphasize the function of distinct nanocatalysts in the synthesis of
various nitrogen-containing heterocyclic compounds. An update on the catalytic efficiency of different
nanocatalysts, such as magnetic nanocatalysts, nanomixed metal oxides, core-shell nanocatalysts,
nano-supported catalysts, and graphene-based nanocatalysts for the production of heterocycles has
been provided in this article.
Deciphering the Correlation between the Emergence of Lung Carcinoma Associated with Tuberculosis-related Inflammation
Authors: Chauhan Prashant , Pandey Pratibha , Ramniwas Seema , Khan Fahad , Maqsood Ramish
Published: June 2024

Lung cancer and tuberculosis (TB) are classified as the second-most life-threatening
diseases globally. They both are exclusively represented as major public health risks and might
exhibit similar symptoms, occasionally diagnosed simultaneously. Several epidemiological
studies suggest that TB is a significant risk factor for the progression of lung cancer. The staggering
mortality rates of pulmonary disorders are intrinsically connected to lung cancer and TB.
Numerous factors play a pivotal role in the development of TB and may promote lung carcinogenesis,
particularly among the geriatric population. Understanding the intricacies involved in
the association between lung carcinogenesis and TB has become a crucial demand of current
research. Consequently, this study aims to comprehensively review current knowledge on the
relationship between tuberculosis-related inflammation and the emergence of lung carcinoma,
highlighting the impact of persistent inflammation on lung tissue, immune modulation, fibrosis,
aspects of reactive oxygen species, and an altered microenvironment that are linked to the progression
of tuberculosis and subsequently trigger lung carcinoma.
Androgen Signaling in Prostate Cancer: When a Friend Turns Foe
Authors: Pandey Swaroop Kumar , Sabharwal Usha , Tripathi Swati , Mishra Anuja , Yadav Neha , Dwivedi-Agnihotri Hemlata
Published: June 2024

Androgen (AR) signaling is the main signaling for the development of the prostate
and its normal functioning. AR is highly specific for testosterone and dihydrotestosterone, significantly
contributing to prostate development, physiology, and cancer. All these receptors
have emerged as crucial therapeutic targets for PCa. In the year 1966, the Noble prize was
awarded to Huggins and Hodge for their groundbreaking discovery of AR. As it is a pioneer
transcription factor, it belongs to the steroid hormone receptor family and consists of domains,
including DNA binding domain (DBD), hormone response elements (HRE), C-terminal ligand
binding domain (LBD), and N-terminal regulatory domains. Structural variations in AR, such as
AR gene amplification, LBD mutations, alternative splicing of exons, hypermethylation of AR,
and co- regulators, are major contributors to PCa. It’s signaling is crucial for the development
and functioning of the prostate gland, with the AR being the key player. The specificity of AR
for testosterone and dihydrotestosterone is important in prostate physiology. However, when it
is dysregulated, AR contributes significantly to PCa. However, the structural variations in AR,
such as gene amplification, mutations, alternative splicing, and epigenetic modifications, drive
the PCa progression. Therefore, understanding AR function and dysregulation is essential for
developing effective therapeutic strategies. Thus, the aim of this review was to examine how
AR was initially pivotal for prostate development and how it turned out to show both positive
and detrimental implications for the prostate.
Rapid Metabolism of Monthly Extended-Release Buprenorphine
Formulation: A Case Report
Authors: Tolba Hossameldin , Foad Wael , El Hayek Samer
Published: June 2024

Background:

Medication-assisted treatment constitutes the gold standard management
for patients with opioid use disorder. Many factors can alter the response to medications, including
genetic variations. In this case report, we discuss the presentation of a patient maintained on subcutaneous
extended-release buprenorphine formulation who repeatedly presented objective and subjective
signs of opioid withdrawal when he was switched from weekly to monthly formulation. We
particularly highlight the role of metabolic pharmacogenes in this presentation.

Case Presentation:

Mr. Y, a 31-year-old single man, presented to our rehabilitation center seeking
assistance for his polysubstance dependence, mainly opioid use disorder. As part of his multidisciplinary
treatment plan, he was started on weekly extended-release buprenorphine. After maintenance
for several months, he was transitioned to the monthly equivalent formulation. Since the transition,
he began to develop severe withdrawal symptoms 1-2 weeks before his next due injection.
This was paralleled by a noted decrease in buprenorphine level on his urine drug screening test. As
soon as the patient was placed back on the weekly formulation, his symptoms resolved.

Conclusion:

This is a novel case highlighting the potential role of pharmacogenomics in clinical
presentation and response to medications. Switching patients from weekly to monthly extendedrelease
buprenorphine formulation might make rapid or ultra-rapid metabolizers at risk of earlyonset
withdrawal symptoms. =In such a case, earlier provision of the injection or switching to another
formulation or medication can be considered.
Nicotianamine as a Potential Active Component of Lotus Seed Extract for Inhibiting Angiotensin-converting Enzyme
Authors: Nishibori Naoyoshi , Morita Kyoji , Sagara Takefumi
Published: June 2024

Aims:

Hypertension is one of the chronic diseases causing a serious health problem in many countries worldwide. Therefore, the prevention and amelioration of hypertension with medicinal food is considered to be important for maintaining good health and well-being. The main objective of this study is to verify that the extract of lotus seed has a significant inhibitory effect on the angiotensin I-converting enzyme (ACE).

Background:

Lotus (Nelumbo nucifera) is well known to have a variety of biological and med-ical activities and is popularly used as a traditional medicinal food in several East Asian coun-tries. In a previous study, we reported that the aqueous extract of lotus root used as a popular foodstuff caused an inhibitory effect on the angiotensin I-converting enzyme (ACE), suggesting its possible effectiveness for improving high blood pressure.

Objective:

The purpose of the present study was to reveal the effect of lotus seed extract on ACE activity and to identify a potentially active component of the extract originating from lotus seed.

Methods:

The ACE inhibitory activity was determined using Hippuryl-L-histidyl-L-leucin (HHL) as substrate, and the amount of hippuric acid formed enzymatically was determined using an HPLC system.

Results:

The lotus seed extract was shown to strongly inhibit the ACE activity, thus ameliorating the hypertensive state. Furthermore, the fractionation of the lotus seed extract provided evidence for suggesting nicotianamine as a putative ACE-inhibiting component contained in the extract.

Conclusion:

These findings were considered to propose the possibility that the lotus seed and the lotus root might benefit patients with hypertension.
Pembuatan Peta Curah Hujan untuk Evaluasi Kesesuaian Rencana Tata Ruang Kawasan Hutan Kabupaten Bogor
Authors: Setiawan Heri , Wibowo Adi , Supriatna Supriatna
Published: June 2024

Spatial Multi Criteria Analysis (SMCA) digunakan untuk menentukan peta kesesuaian kawasan hutan yang disusun dari berbagai peta variabel termasuk peta curah hujan. Tujuan dari penelitian ini adalah membuat peta curah hujan di Kabupaten Bogor dari data Climate Hazards Group InfraRed Precipitation with Station data (CHIRPS). Data yang digunakan adalah data CHIRPS bulanan 2011 – 2020 sebanyak 120 file format raster. Data tersebut diolah menjadi data rata – rata tahunan sebanyak satu file format raster dengan cell statistics tools. Kemudian dilakukan ekstraksi menjadi titik, interpolasi kriging dan reklasifikasi. Hasilnya menunjukkan peta curah hujan sebelum dilakukan reklasifikasi terdapat tujuh kelas dengan nilai curah hujan antara 2.334,18 - 4.708,36 mm/tahun. Setelah dilakukan reklasifikasi rata – rata curah hujan terdapat tiga kelas yaitu sedang (2.000 – 3.000 tahun) seluas 8,02%, tinggi (3.000 – 4.000) seluas 61,08% dan sangat tinggi ( 4.000 mm/tahun) seluas 30,90% dari total luas Kabupaten Bogor. Rencana Tata Ruang Kawasan Hutan di Kabupaten Bogor mempunyai potensi kesesuaian yang tinggi karena wilayah ini didominasi oleh tingkat curah hujan tinggi dan sangat tinggi.
The role of bank governance in managing the risks associated with banking institutions
Authors:   Accounting Department, College of Business, Jouf University, Sakaka, Saudi Arabia, Alnor Nasareldeen Hamed Ahmed , Mohammed Omer Alsir Alhassan ,   Accounting Department, Faculty of Economics and Administrative Sciences, Islamic University of Minnesota, Virginia, USA, Al-Matari Ebrahim Mohammed ,   Accounting Department, College of Business, Jouf University, Sakaka, Saudi Arabia,   Faculty of Commerce and Economics, Amran University, Amran, Yemen, Ahmed Alsadig ,   Applied College at Muhyle, King Khalid University, Muhyle, Saudi Arabia, Benlaria Houcine ,   Business Administration Department, College of Business, Jouf University, Sakaka, Saudi Arabia, Elhefni Ahmed Hesham Moawed ,   Finance and Investment Department, College of Business, Jouf University, Sakaka, Saudi Arabia, Kouki Fadoua ,   Applied College at Muhyle, King Khalid University, Muhyle, Saudi Arabia, Elshaabany Mona M. ,   Accounting Department, College of Business, Jouf University, Sakaka, Saudi Arabia
Published: June 2024

This study explores the crucial role of bank governance in maintaining financial system stability by managing risks within banks. It differentiates from prior research by not solely focusing on the 2008 financial crisis. Data from a survey of 220 bank employees were analyzed using structural equation modeling. Key findings include the necessity of well-informed boards and robust governance structures that adhere to regulations for effective risk management. Open communication with stakeholders and stringent control over technological risks are also vital due to the banking sector's increased technology reliance. These insights underscore the complexities of risk management in banking governance, stressing the need for a comprehensive, adaptable strategy. This research contributes new evidence to the importance of strong governance in risk management, with significant implications for bank and corporate governance fields. The study's model demonstrates high predictive accuracy and explanatory power.
Clima y Satisfacción Laboral En Funcionarios Del Sector Salud
Authors: Gutiérrez-Calderón María , Paternina-Avilez Yadid , González-Payares Danys , Mercado-Martínez Ximena , Acosta-Guerra Liceth
Published: June 2024

Objetivo: El artículo presenta los hallazgos de una investigación que tuvo como objetivo establecer la relación entre el clima y la satisfacción laboral de los empleados de una ESE proveedora de servicios de salud en el período postpandemia. Método: El estudio adoptó un enfoque cuantitativo, de tipo correlacional y diseño transversal, donde participaron 21 trabajadores de la institución. Se utilizaron encuestas tipo Likert para medir el clima laboral y el cuestionario de Satisfacción S21/26 (Meliá y Peiró, 1998) para evaluar la satisfacción laboral. Resultados: Se encontró que el clima laboral en la ESE es mayormente favorable, aunque los principales desafíos están relacionados con los estilos de liderazgo. En cuanto a la satisfacción laboral, en general es positiva, pero existen áreas de menor satisfacción, como los estilos de supervisión, la carga de trabajo y las condiciones de trabajo precarias. Se observó una relación entre ambas variables, donde los aspectos negativos del ambiente laboral influyen en la satisfacción percibida por los empleados. Conclusiones: Los resultados respaldan la relación directa entre el clima y la satisfacción laboral, destacando la importancia de mejorar el ambiente laboral para aumentar la satisfacción de los trabajadores.
Addressing Hospital Overwhelm During the COVID-19 Pandemic by Using a Primary Health Care–Based Integrated Health System: Modeling Study
Authors: Huang Jiaoling , Qian Ying , Yan Yuge , Liang Hong , Zhao Laijun
Published: June 2024

Background

After strict COVID-19–related restrictions were lifted, health systems globally were overwhelmed. Much has been discussed about how health systems could better prepare for future pandemics; however, primary health care (PHC) has been largely ignored.

Objective

We aimed to investigate what combined policies PHC could apply to strengthen the health care system via a bottom-up approach, so as to better respond to a public health emergency.

Methods

We developed a system dynamics model to replicate Shanghai’s response when COVID-19–related restrictions were lifted. We then simulated an alternative PHC-based integrated health system and tested the following three interventions: first contact in PHC with telemedicine services, recommendation to secondary care, and return to PHC for recovery.

Results

The simulation results showed that each selected intervention could alleviate hospital overwhelm. Increasing the rate of first contact in PHC with telemedicine increased hospital bed availability by 6% to 12% and reduced the cumulative number of deaths by 35%. More precise recommendations had a limited impact on hospital overwhelm (<1%), but the simulation results showed that underrecommendation (rate: 80%) would result in a 19% increase in cumulative deaths. Increasing the rate of return to PHC from 5% to 20% improved hospital bed availability by 6% to 16% and reduced the cumulative number of deaths by 46%. Moreover, combining all 3 interventions had a multiplier effect; bed availability increased by 683%, and the cumulative number of deaths dropped by 75%.

Conclusions

Rather than focusing on the allocation of medical resources in secondary care, we determined that an optimal PHC-based integrated strategy would be to have a 60% rate of first contact in PHC, a 110% recommendation rate, and a 20% rate of return to PHC. This could increase health system resilience during public health emergencies.
Evaluating and Enhancing Large Language Models’ Performance in Domain-Specific Medicine: Development and Usability Study With DocOA
Authors: Chen Xi , Wang Li , You MingKe , Liu WeiZhi , Fu Yu , Xu Jie , Zhang Shaoting , Chen Gang , Li Kang , Li Jian
Published: June 2024

Background

The efficacy of large language models (LLMs) in domain-specific medicine, particularly for managing complex diseases such as osteoarthritis (OA), remains largely unexplored.

Objective

This study focused on evaluating and enhancing the clinical capabilities and explainability of LLMs in specific domains, using OA management as a case study.

Methods

A domain-specific benchmark framework was developed to evaluate LLMs across a spectrum from domain-specific knowledge to clinical applications in real-world clinical scenarios. DocOA, a specialized LLM designed for OA management integrating retrieval-augmented generation and instructional prompts, was developed. It can identify the clinical evidence upon which its answers are based through retrieval-augmented generation, thereby demonstrating the explainability of those answers. The study compared the performance of GPT-3.5, GPT-4, and a specialized assistant, DocOA, using objective and human evaluations.

Results

Results showed that general LLMs such as GPT-3.5 and GPT-4 were less effective in the specialized domain of OA management, particularly in providing personalized treatment recommendations. However, DocOA showed significant improvements.

Conclusions

This study introduces a novel benchmark framework that assesses the domain-specific abilities of LLMs in multiple aspects, highlights the limitations of generalized LLMs in clinical contexts, and demonstrates the potential of tailored approaches for developing domain-specific medical LLMs.
Decoding the Contexts: A Natural Language Processing Analysis of Peer and Family Dynamics in Teenage Substance Use Online Discussions (Preprint)
Authors: Zhu Jianfeng , Zhang Xinyu , Jin Ruoming , Kenne Deric R
Published: June 2024

BACKGROUND

Substance use among adolescents represents a significant public health concern. Despite research on the influence of contextual factors on teenage substance use, the nuances of these contexts and associated emotions remain underexplored, particularly within online communities.

OBJECTIVE

This study aims to decode the context factors, emotion tones, and topics discussed in substance use-related posts within the r/teenager subreddit. We introduce an innovative approach leveraging natural language processing to analyze discussions within a large online community of teenagers on Reddit.

METHODS

We collected 31,724 substance use-related posts from the r/teenagers subreddit in English, spanning from 2018 to 2023. A mixed methods was applied on these posts, including trend analysis to explore the dynamic context within the data. The BERT family of models was used to extract sentiment and topic features.

RESULTS

The analysis revealed that "drink" and "weed" were the most frequently mentioned substances among teenagers. Peaks in discussions occurred during summer months, particularly in July 2023. Substance use posts exhibited higher levels of negative emotions such as annoyance, sadness, and disappointment. Family dynamics significantly impacted the teenage substance use environment and behaviors. The term "Dad" was commonly associated with familial roles and the setting of examples within the household, particularly regarding habits and behaviors around substance consumption and addiction. The term "Mum" was often at the forefront of familial discussions about marijuana and smoking cessation.

CONCLUSIONS

The study's findings provide deeper insights into the multifaceted nature of substance use discussions among teenagers, informing potential intervention strategies and future research directions. The authors underscore the need for targeted interventions addressing peer influence, familial communication, and emotional well-being in mitigating adolescent substance use.
Analyzing the Performance of Explainable Machine Learning Models in Risk Factor Identification for Major Cancers (Preprint)
Authors: Huang Xiayuan
Published: June 2024

BACKGROUND

Cancer is a life-threatening disease and a leading cause of death worldwide, with an estimated 611,000 deaths and over 2 million new cases in the United States in 2024. The rising incidence of major cancers, including among younger individuals, highlights the need for early screening and monitoring of risk factors to manage and decrease cancer risk.

OBJECTIVE

To identify pivotal factors essential for predicting the risk factors for four major cancer types (breast, colorectal, lung, and prostate) through the utilization of explainable machine learning techniques is imperative due to the increasing burden of cancer patients.

METHODS

De-identified electronic health record data from MIMIC-III was used to identify patients with four types of cancer who had longitudinal hospital visits prior to receiving a cancer diagnosis. Their records were matched and combined with those of patients without cancer diagnoses using propensity scores based on demographic factors. Three advanced models, penalized Logistic Regression (LR), Random Forest (RF), and Multilayer Perceptron (MLP), were conducted to identify the rank of risk factors for each cancer type, with feature importance analysis for RF and MLP models. The Rank Biased Overlap was adopted to compare the similarity of ranked risk factors across cancer types.

RESULTS

Our framework evaluated the prediction performance of explainable ML models, in which MLP achieved an AUC of 0.78 for breast cancer, 0.76 for colorectal cancer, 0.84 for lung cancer, and 0.78 for prostate cancer, respectively. In addition to demographic risk factors, the most prominent non-traditional risk factors overlapped across models and cancer types, including hyperlipidemia, diabetes, depressive disorders, heart diseases, and anemia. The similarity analysis indicated the unique risk factor pattern for lung cancer from other cancer types.

CONCLUSIONS

The study's findings demonstrate the effectiveness of explainable ML models in predicting non-traditional risk factors for major cancers and highlight the importance of considering unique risk profiles for different cancer types. These insights may contribute to efficient cancer screening and tailored cancer prevention strategies, which, in turn, offer fundamental support for clinical decision-making processes.
Synthesis of Chitosan Silica Membrane from Petung Bamboo (Dendrocalamus asper) Leaves and Its Application as Pb(II) Metallic Adsorbent
Authors: Hasri Hasri , Pratiwi Diana Eka , Safitri Isriyanti , Negara Satria Putra Jaya
Published: June 2024

Membrane synthesis through a phase inversion method using chitosan and sodium silicate solutions has been conducted. This research aims to characterize the silica chitosan membrane (SCM) of petung bamboo leaves and determine the synthesized product's adsorption capacity for Pb(II) ions. The XRF characterization showed the silica content of petung bamboo leaves with a percentage of 78.03%. SEM analysis before adsorption is around 13.0 μm, and the pore diameter after adsorption is around 9.7 μm. The results of adsorption analysis of Pb(II) metal using AAS showed that the SCM variation A at an initial concentration of 10.0000 ppm Pb(II) metal adsorbed was 9.8101 ppm, and at an initial concentration of 25.0000 ppm Pb(II) metal was 22.3421 ppm. The variation B at an initial concentration of 10.0000 ppm Pb(II) metal adsorbed was 9.8870 ppm and at an initial concentration of 25.0000 ppm Pb(II) metal adsorbed was 23.5806 ppm. The variation C at an initial concentration of 10.0000 ppm Pb(II) metal adsorbed was 9.9639 ppm, and at an initial concentration of 25.0000 ppm Pb(II) metal was 24.1855 ppm. The results of this research conclude that the highest SCM adsorption power is variation C (2%:22.95%) with a percentage of 99.63%.
Evaluation of Lead Ion in the Wastewater of the Lifting and Treatment Stations Using ICP-MS and CPE Methods
Authors: Hussain Mohammed Nasser , Khudhair Ahmed Fadhil , Ahmed Hussain Jawad
Published: June 2024

To pre-concentrate trace amounts of lead before determining it by UV-vis spectrophotometer, a new method for micelle-mediated phase separation has been created. The process depends on the extraction of lead from iodine media using Triton X-114 in the cloud point extraction method without the need for any chelating agents, where the optimal conditions for the method were achieved, which temperature 50 °C, pH 4, and 30 mmol L−1 concentration of KI, 0.3 mL of 2% (v/v) Triton X-114, and time of 10 min in the water bath. Linearity was followed between 1 and 16 µg/mL of lead concentration. The method's lead detection limit is 0.1 µg/mL and %RSD 3.633. Additionally, the interference impact of certain cations was evaluated. The proposed technique was successfully applied to determine the lead ion in the wastewater in ten different stations in the center and district of Al-Hur in Karbala City. The lead ion of the wastewater of the stations under study was also determined directly using inductively coupled plasma-mass spectrometry (ICP-MS) technology comparing its results with the new method and performing the statistical analysis of both methods. The p-value was less than 0.05, showing significant differences between both methods.
Jardín de San Marcos de la ciudad de Aguascalientes, un referente arquitectónico
Authors: Villanueva Clavel Jorge Guadalupe , Sánchez Silva Iván Israel , Esparza Jiménez Vicente Agustín
Published: June 2024

El Jardín de San Marcos es de uno de los espacios culturales más emblemáticos de la ciudad de Aguascalientes, es sede de la Feria Nacional de San Marcos, que recibe miles de visitantes al año, convirtiéndolo en el espacio público más visitado del estado. A pesar de esta condición, la historia del Jardín sigue sin ser contada desde sus vestigios materiales, centrándose en la feria como evento social, político y económico de la ciudad.
Es por lo anterior que el objetivo de este artículo es mostrar el proceso de transformación histórica y arquitectónica del Jardín y su contexto inmediato, retomando aspectos históricos desde la fundación de la Villa de Nuestra Señora de la Asunción de las Aguascalientes y su relación con el pueblo de indios de San Marcos, sin dejar de lado los arquitectónicos que permitan recrear y describir su conformación, diseño y construcción dentro de los criterios de las corrientes internacionales de la época.
Los muebles de concreto del arquitecto Edmundo Rodríguez
Authors: Solano Rojas Aldo
Published: June 2024

Durante la década de 1970 los espacios públicos de Ciudad de México fueron sujeto de un ambicioso programa de remodelación urbana liderado por el arquitecto Joaquín Álvarez Ordóñez, entonces director de la Secretaría de Obras Públicas del Departamento del Distrito Federal. El encargado de diseñar el mobiliario urbano y de cuidar la imagen de los parques y jardines renovados fue el joven arquitecto Edmundo Rodríguez Saldívar, quien ya contaba con experiencia en el diseño de espacios públicos desde años antes. Este texto presenta el trabajo de Rodríguez quien, debido a su corta carrera y a haberse especializado en un género ignorado por la historiografía como es el mobiliario urbano, estaba prácticamente ausente de la historia del arte y de la arquitectura.
Correspondencia de Hannes Meyer a Carlos Leduc 1938-1939. Documentos inéditos
Authors: Drago Quaglia Elisa
Published: June 2024

Correspondencia de Hannes Meyer a Carlos Leduc 1938-1939. Documentos inéditos
Semantic dynamics of the lexeme ‘pensioner’ in Russian linguistic culture
Authors: Denisenko Vladimir N. , Safaralieva Lyubov A. , Perfilyeva Natalia V.
Published: June 2024

Socio-economic changes, reforms of the pension system have transformed the perception of old age by Russian language native speakers. The authors deal with the dynamics of the semantic volume of the lexeme ‘pensioner’, caused by the above-mentioned extra-linguistic factors. The aim of the study is to describe the semantic transformation of the lexeme ‘pensioner’ representing the concepts ‘pensioner’, ‘pension’ and ‘old age’. The material of the research was the data of the National Corpus of the Russian Language for the period from 1995 to 2021, lexicographic sources, data of the associative experiment, which identified the conceptual, value-oriented and image-bearing components of the concepts ‘pensioner’, ‘pension’ and ‘old age’. The method of analysis and generalization of linguistic material from lexicographic sources, associative experiment, and the method of component analysis were used. The analysis of verbal elements reflecting cultural, traditional and value representations of Russian language speakers presented the dynamics of the semantics of the lexeme ‘pensioner’, its semantic transformation, which reflects changes in the Russian linguistic world picture. Semantic merisms identified as a result of contrastive analysis of potential associations allowed to present the semantic volume of the word considering the extra-linguistic data. As a result, the data were obtained, which can be used in lexicographic sources when defining the lexeme ‘pensioner’. Theoretical and practical approaches to modeling of Russian linguistic-cultural concepts are generalized. This reveals cultural and moral dominants of Russian language speakers and sacred meanings of the Russian culture.