bluuebunny/crossref_metadata_2025 huggingface dataset:
Practical One Pot Synthesis of 2-Alkyl-substituted Benzothiazoles from Bis-(2-nitrophenyl)-disulfides.
Authors: Puskov Volodymyr , Babii Serhii , Adamenko Iryna , Melnychuk Sviatoslava , Druzhenko Tetiana , Lyapunov Alexander , Popov Sergey , Volochnyuk Dmytro , Ryabukhin Serhiy
Published: March 2024

2-Methyl benzothiazoles are widely used as key precursor for dyes, photosensitizers and fluorescent markers. Therefore, they are demanded in multigram and even kilogram amounts. Hereby, we propose a scalable single-step procedure for production of 2-alkylsubstituted benzothiazoles from corresponding bis-(2-nitrophenyl)-disulfides. Substrates containing various substituents including carboxylic and ester groups were introduced into reaction. Different sodium salts were tested as reducing agents, extensive optimization was performed. The products were obtained in the amounts of up to 350 g in a single run.
Effect of Microhydration in Tuning the Photophysical Behavior of a Luminescent DNA Probe Revealed by Non-Adiabatic Dynamics
Authors: Lognon Elise , Burger Alain , Dumont Elise , Monari Antonio
Published: March 2024

We report the non-adiabatic dynamics, performed in the surface hopping formalism, of an environment-dependent luminescent organic DNA probe. In particular we have shown that the first shell solvent water molecules undergo a rather complex reorganization upon light excitation. This involves also the triggering of a water-mediated proton transfer process which leads to the formation of the tautomeric structure. The presence of this solvent-mediated transfer mechanism globally diminishes the intersystem crossing efficiency, and hence the population of the triplet state manifold, as compared to the non-solvated systems. Our results also point out the non-innocent role of solvent networks in tuning complex photophysical processes, while opening competitive relaxation channels.
Flavin-Mediated Reductive Deiodination: Conformational Events and Reactivity Pattern in the Active Site of Human Iodotyrosine Deiodinase
Authors: Karmakar Soumyajit , Mishra Sabyashachi
Published: March 2024

Human iodotyrosine deiodinase (hIYD) catalyzes the reductive deiodination of iodotyrosine using a flavin mononucleotide cofactor to maintain iodine concentration in the body. Mutations in the hIYD gene are linked to human hypothyroidism, emphasizing its role in thyroid function regulation. The present work employs microsecond-scale molecular dynamics simulations and quantum chemical calculations to elucidate the conformational dynamics and reactivity in the active site at various stages of hIYD catalysis. The flavin is found to employ a unique butterfly motion of its isoalloxazine ring accompanied by a novel active-and-resting state of its ribose 2′-OH group during the catalytic cycle. The flavin dynamics is found to control substrate binding affinity, the active site lid closure, and NADPH recognition. The enzyme uses a group of basic residues (R100, R101, R104, K182, and R279) to stabilize flavin at different stages of catalysis, suggesting potential mutations to control enzyme activity. The reactivity descriptor analysis and stereo-electronic analysis predict the N5 nitrogen of flavin as a proton source during the reductive deiodination. The present findings provide key insights into the molecular basis of hIYD activity and lay the groundwork for future research aimed at therapeutic interventions and industrial applications.
تأثير استخدام برنامج تعلیمی لسرعة الاستجابة الحركية وفقاً للإستجابات السمعية والبصرية في دقة استلام الكرة لبعض انواع المناولات في كرة السلة
Authors: Karim Omar A.
Published: March 2024

تأثير استخدام برنامج تعلیمی لسرعة الاستجابة الحركية وفقاً للإستجابات السمعية والبصرية في دقة استلام الكرة لبعض انواع المناولات في كرة السلة

الباحث م.د عمر عالي كريم  omar.karim@soran.edu.iq  

ملخص البحث

         ان التطور الحاصل في لعبة كرة السلة جاءت نتيجة الدراسات والبحوث في هذا المجال، واستلام الكرة هي المهارة الوحيدة التي لم يتناولها الباحثون على حد علم الباحث وهي من المهارات الاساسية الهجومية المهمة سواء كان بمفردة عند أستلام الكرة  من قبل اللاعب والاحتفاظ بها  في الخطوة اللاحقة عندما يستخدم اللاعب الكرة للمحاورة او المناولة او التهديف وفكرة استخدام تمرينات سرعة الاستجابة الحركية جاءت لتطوير دقة أستلام الكرة لبعض المناولات في كرة السلة، إذ يهدف البحث الى الكشف عن تأثير البرنامج التعليمي لسرعة الاستجابة الحركية وفقا للإستجابات السمعية والبصرية في دقة استلام الكرة لبعض  من انواع المناولات في كرة السلة .واستخدم الباحث المنهج التجريبي لملاءمته مع طبيعة البحث، وتكون مجتمع البحث من لاعبي منتخب جامعة سوران لكرة السلة والبالغ عددهم (16) لاعباُ تم استبعاد( 4 )لاعبين لغرض التجربة الاستطلاعية ،اما عينة البحث الرئيسة فكانت (12)لاعباً تم تقسيمهم الى مجموعتين كل مجموعة من (6) لاعبين، استخدمت المجموعة الاولى برنامج  تعليمي لسرعة الاستجابة الحركية وفقاً للاستجابات السمعية والمجموعة التجريبية الثانية استخدمت البرنامج التعليمي لسرعة الاستجابة الحركية وفقاً للإستجابات البصرية ، واستخدم الباحث تقيم فن الاداء المهاري كأداة البحث لقياس استلام الكرة لبعض مناولات كرة السلة ، واستخدم الباحث برنامج (SPSS) لمعالجة البيانات الاحصائية . إذ تم توصل الى عدة الاستنتاجات منها:- 

اظهرت النتائج بان استخدام البرنامج التعليمي لسرعة الاستجابة الحركية وفقاً للاستجابات السمعية كان له تأثير ايجابي وفعال في دقة استلام الكرة لبعض المناولات (المناولة الصدرية –المناولة المرتدة – المناولة من فوق الرأس) في كرة السلة .

اظهرت النتائج بان استخدام البرنامج التعليمي لسرعة الاستجابة الحركية وفقاً للاستجابات البصرية كان له تأثير ايجابي وفعال في دقة استلام الكرة لبعض المناولات (المناولة الصدرية –المناولة المرتدة – المناولة من فوق الرأس) في كرة السلة .

لم تظهر فروق معنوية في الاختبار البعدي بين المجموعتين التجريبيتين في دقة استلام الكرة لبعض المناولات  (المناولة الصدرية –المناولة المرتدة –المناولة من فوق الرأس) في كرة السلة .

الكلمات المفتاحية : السرعة الاستجابة الحركية –الاستجابات السمعية والبصرية –استلام الكرة –انواع المناولات في كرة السلة .×
KAJIAN METAFORA DAN METONIMI PADA IKLAN GUDANG GARAM “NYALAKAN MERAHMU”
Authors: Sidabutar Usman , Mulyadi Mulyadi
Published: March 2024

Kajian metafora dan metonimi dalam perluasan iklan Gudang Garam baik secara visual dan verbal menyampaikan berbagai pemahaman. Penelitian difokuskan pada penggunaan metaforisasi dan metonimisasi dalam iklan Gudang Garam. Dalam iklan Gudang Garam tersebut termuat nyalakan merahmu yang dirujuk untuk menarik perhatian banyak pendengar maupun pembaca. Ekspresi nyalakan merahmu yang terdiri dari dua kata namun bisa menyampaikan konseptual yang berfungsi untuk memfasilitasi pemahaman yang lebih luas. Metode penelitian ini adalah metode penelitian deskriptif kualitatif. Prosedur penentuan metafora dan metonimi yang digunakan dalam penelitian ini adalah prosedur MIPVU (Steen, 2015). Hasil penelitian ini memberikan gambaran keseluruhan yang koheren tentang mengapa banyak metafora yang dapat diartikan sebagai metonimi dan mengapa banyak metonimi dapat dianggap sebagai metafora. Alasannya tampaknya, dalam kasus metafora korelasional, antara nonfiguratif dan tahap metafora ada tahap metonimik. Diberikan bingkai di mana korelasi berlaku antara dua elemen, harus ada hubungan metonimi yang sebelumnya logis antara elemen-elemen tersebut sebelum satu elemen dipindahkan dari kerangka awal untuk membentuk kerangka baru dan independen. Bingkai, yang akan membentuk sumber metafora atau target. Kesimpulan penelitian ini adalah metafora berbasis korelasi muncul dari representasi konteks dan teks sebagai mental seperti bingkai konkordansi yang memiliki padanan makna yang berbeda sesuai dengan tahap metonimik.tentang konseptual metafora dan metonimi khususnya dalam pembuatan iklan maupun pemberian informasi.
Patterns of Interactions of the Complex City System: Emotional Urban Objects as Triggering Agents – A Secondary Publication
Authors: Gonzalez O. A. , Sosa Compeán Liliana Beatriz
Published: March 2024

This article presents an analysis of the patterns of interactions resulting from the positive and negative emotional events that occur in cities, considering them as complex systems. It explores, from the imaginaries, how certain urban objects can act as emotional agents and how these events affect the urban system as a whole. An adaptive complex systems perspective is used to analyze these patterns. The results show patterns in the processes and dynamics that occur in cities based on the objects that affect the emotions of the people who live there. These patterns depend on the characteristics of the emotional charge of urban objects, but they can be generalized in the following process: (1) immediate reaction by some individuals; (2) emotions are generated at the individual level which begins to generalize, permuting to a collective emotion; (3) a process of reflection is detonated in some individuals from the reading of collective emotions; (4) integration/significance in the community both at the individual and collective level, on the concepts, roles and/or functions that give rise to the process in the system. Therefore, it is clear that emotions play a significant role in the development of cities and these aspects should be considered in the design strategies of all kinds of projects for the city. Future extensions of this work could include a deeper analysis of specific emotional events in urban environments, as well as possible implications for urban policy and decision making.
The Limits of Domestic Spatiality in the Information Age – A Secondary Publication
Authors: Lozano de Poo Juan Manuel
Published: March 2024

The limits of spatiality have blurred in the information age; a phenomenon that can be observed through thesocio-spatial implications of Internet use in the domestic sphere. How and why are the use and organization of space-time around the Internet shaping a new domestic spatiality that intertwines the digital space with the production of social space through the practice of habits, presence, and interaction of individuals? What are the repercussions of the superimposition of digital space on human existence? The units of analysis were integrated through the sum of people and middle-class housing in the face of the digitalization process in the city of San Luis Potosi, Mexico. The questionnaire consisted of 35 questions designed from the Likert scale under the thematic order of presence, interaction, and habituality. The data were analyzed using SPSS software. This research contributes to explaining the current period in the history of inhabitable space, dominated by the simultaneous interrelationships between individuals, digital space, and architecture, which result in the detachment and devaluation of physical domestic space, while also highlighting the lack of control and regulation of individuals over the Internet.
Level of blood glucose, fatigue and sexual anxiety in diabetes mellitus sufferers
Authors: Karyati Sri , Kusumaningrum Rafika Putri Ayu , Siswanti Heny , Suwandi Edi Wibowo
Published: March 2024

Diabetes causes a decrease in glycogen which results in fatigue and neurovascular disorders which cause a decrease in body organ function. This condition raises their concerns about sexual problems in themselves and this is the main trigger for sexual problems in DM sufferers apart from physical problems. This study aims to determine the relationship between blood glucose levels and fatigue levels with sexual anxiety in diabetes mellitus sufferers. This research is correlational quantitative research with a cross-sectional time approach. The population of this study were DM sufferers in the Nalumsari Community Health Center working area with a sample of 36 people. The results of the analysis using the Spearman rho test obtained a P value of 0.000 so it can be concluded that there is a significant relationship between blood glucose levels and levels of fatigue and sexual anxiety in diabetes mellitus sufferers in the Nalumsari I Regional Health Center working area.
Black garlic for cholesterol in the community of Kudus District, Central Java
Authors: Sukesih Sukesih , Siswanti Heny , Mubarok Moh Zaki
Published: March 2024

High cholesterol is a health problem for the body because it can cause several diseases, including heart disease, stroke, and diabetes mellitus. An increase in cholesterol in the blood can be prevented by using the active substance in garlic in the form of aliin. Allin is a chemical containing sulfur which gives garlic its distinctive aroma. The research aimed to determine the effect of black garlic on cholesterol in the community of Purwosari Kudus Village. The quasi-experimental method with pretest-posttest control group design data analysis using paired t-test and independent test of giving garlic using SOP. The research population was 40 respondents, a research sample of 34 respondents using a purposive sampling technique consisting of 17 respondents in the intervention group and 17 respondents in the control group. The results of the research show that there is an effect of black garlic on cholesterol in the community in Purwosari Kudus Village in the intervention group with a statistical test with a p-value of 0.000 < 0.05.
The effect of stress on the epilepsy recurrence
Authors: Hartinah Dewi , Tristanti Ika , Yulisetyaningrum Yulisetyaningrum , Annisah Yuni
Published: March 2024

Epilepsy is a health problem that is both a medical problem and a social problem. This study aimed to determine the relationship between stress levels and recurrence rates in epilepsy patients at Dr Loekmonohadi Kudus Hospital. This research uses a descriptive correlation type of research, the approach method uses cross-sectional, the population in this study are all epilepsy patients and are registered in the medical record at Dr Loekmonohadi Kudus Regional Hospital in the period August 2023, there are 51 patients with a sample of 45 respondents. The measuring instrument used is the test. Spearman Rank Correlation. The results of the analysis showed a p-value of 0.094 > (α = 0.05). It can be concluded that Ha was rejected and Ho was accepted, so there is no relationship between stress levels and recurrence rates in epilepsy patients at Kudus Hospital in 2023
PEMANFAATAN NANO APP: APLIKASI PEMBUKUAN PADA UMKM TOKO KELONTONG
Authors: Sakkinah Intan Sulistyaningrum , Sakkinah Intan Sulistyaningrum , Rahmawati Ulfa Emi , Hastuti Puji , Hasanah Qonitatul , Pratama Raditya Arief
Published: March 2024

Pembukuan memiliki peranan penting dalam berbisnis, pembukuan yang baik dapat menjadi patokan dasar dalam melihat keberhasilan dalam berbisnis. Pembukuan dapat menjadi landasan dalam pengambilan keputusan dalam pengelolaan usaha sebagai contoh dalam penetapan harga maupun pengembangan pasar. UMKM Toko Kelontong bu Hermin belum menerapkan sistem pembukuan dalam menjalankan usahanya.  Minimnya pengetahuan mengenai pembukuan yang baik, mengakibatkan pengusaha UMKM kesulitan dalam penerapan pembukuan dan tidak mengetahui aliran dana usahanya. Komponen pembukuan yang banyak membuat pelaku usaha memiliki pemikiran bahwa pencatatan keuangan akan membebani dan menambah pekerjaan baru. Sehingga dari permasalahan yang dihadapi oleh UMKM Toko Kelontong Bu Hermin, penelitian ini memberikan solusi dalam pencatatan keuangan yang lebih praktis dengan menggunakan aplikasi pembukuan NanoApp. Pemilik usaha diberi pelatihan untuk menggunakan aplikasi NanoApp beserta dengan buku panduan menggunakan aplikasi. Berdasarkan hasil pelatihan penggunaan aplikasi, pemilik usaha mendapatkan kemudahan dalam melakukan pencatatan transaksi. Pencatatan barang menjadi lebih sistematis dan catatan pemasukan maupun pengeluaran dapat dimonitor secara langsung. Dengan adanya aplikasi NanoApp, pemilik usaha mendapatkan solusi dari permasalahan yang selama ini dihadapi yaitu tidak adanya pencatatan keuangan.
PENGENALAN FUNGSI DIGITAL MARKETING BAGI SISWA MAN 2 KLATEN
Authors: Bhikuning Dixian , Wasiati Hera , Listyani Indah Putri , Pratama Guntur B L
Published: March 2024

Pemasaran digital merupakan strategi untuk mempromosikan produk atau layanan melalui media sosial, yang telah menjadi sangat penting dalam konteks saat ini. Sebelumnya, perubahan signifikan dalam pendidikan di Indonesia dan di seluruh dunia terjadi setelah situasi pasca pandemi yang mengubah cara siswa dan siswi beroperasi. Sekarang, penggunaan platform digital menjadi semakin umum.Pengabdian Kepada Masyarakat (PKM) Universitas Teknologi Digital Indonesia memberikan kesempatan kepada siswa dan siswi Madrasah Aliyah Negeri 2 Klaten untuk memahami konsep pemasaran digital lebih dalam. Ini tidak hanya mencakup aspek teknis, tetapi juga penerapannya dalam proses belajar mengajar. PKM diadakan di MAN 2 Klaten, Provinsi Jawa Tengah, dengan tujuan memperluas wawasan siswa dan siswi tentang pemasaran digital. Selain itu, kegiatan ini juga memberikan pandangan tentang cara membangun bisnis di era digital dengan memanfaatkan potensi yang ada di Klaten dan sekitarnya. Dengan demikian, diharapkan siswa dan siswi dapat memberikan kontribusi yang lebih besar, tidak hanya bagi diri mereka sendiri dan keluarga, tetapi juga untuk masyarakat di sekitarnya. Metodepelaksanaanyangdigunakandalamkegiatanpengabdianiniadalahmelakukanpelatihandasar-dasar pengetahuan serta membangun mindset yang benar pada digital marketing denganmateriyangdikhususkanuntukmembangun mindset para siswa dan siswi bahwa dengan teknik digital marketing akan jauh lebih mudah dan efisien dalam melakukan penjualan produk maupun jasa ,misalnya bagaimana cara mengetahui produk atau jasa apa yang sedang trending di daerah tertentu, bagaimana dengan menggunakan digital marketing bisa menjadi lebih mudah dalam memasarkan produk maupun jasa secara lebih luas dansebagainya.Selainituakandilakukanpelatihandalammenggali mindset positif dari para siswa tentang betapa mudahnya menjual melalui digital marketing .
PERAN KEPEMUDAAN DALAM UPAYA PENCEGAHAN VIRUS CORONA MELALUI PROGRAM KAMPUNG TANGGUH
Authors: Abibah Khuswatul
Published: March 2024

Virus Corona menyebabkan infeksi COVID-19 yang menimbulkan wabah pandemik baru dengan penyebaran virusyang sangat cepat melalui manusia antar manusia dengan sentuhan atau hubungan komunikasi secara langsung. Sistem tubuh yang diserang dari Virus Corona atau Covid-19 ini ialah sistem pernafasan. Infeksi paru-paru yang sangat berat bahkan kematian serta gangguan ringan pada pernafasan merupakan gejala yang disebabkan oleh Virus Corona tersebut. Mulai dari ibu hamil, menyusui, anak kecil, orang tua, orang dewasa, balita, siapa saja dapat terserang Virus Corona. Hingga detik ini di Indonesia masih melawan Virus Corona ini. Tidak sedikit orang yang melaporkan kematian dan hanya beberapa orang yang melaporkan kesembuhan terkait jumlah kasus Virus Corona yang terus bertambah. Para warga diharapkan akan lebih siap dalam menghadapi permasalahan yang ditimbulkan dari Virus Corona dengan dibentuknya Program Kampung Tangguh, supaya terdapat penekanan penyebaran Virus Corona dan masalah yang timbul dapat diminimalisasi. Program Kampung Tangguh sendiri mengharapkan agar masyarakat dapat membantu pencegahan semakin meluasnya Virus Corona agar tidak meluas didaerah pedesaan.The Corona virus causes the COVID-19 infection which causes a new pandemic outbreak with the spread of the virus very quickly through humans between humans with touch or direct communication relationships. The body system that is attacked by the Corona Virus or Covid-19 is the respiratory system. Lung infections that are very severe and even death and mild respiratory problems are symptoms caused by the Corona Virus. Starting from pregnant women, breastfeeding, small children, the elderly, adults, toddlers, anyone can get Corona Virus. Until now, Indonesia is still fighting the Corona Virus. Not a few people have reported deaths and only a few people have reported recovery due to the increasing number of Corona Virus cases. It is hoped that the residents will be better prepared to deal with the problems caused by the Corona Virus with the establishment of the Tangguh Village Program, so that there is an emphasis on the spread of the Corona Virus and the problems that arise can be minimized. The Tangguh Village Program itself hopes that the community can help prevent the further spread of the Corona Virus so that it does not spread in rural areas.
Las comunidades indígenas de Hidalgo. Ixmiquilpan Volumen III
Authors: Quezada Ramírez María Félix
Published: March 2024

Como resultado del proyecto catálogo de pueblos y comunidades indígenas del Estado de Hidalgo, este documento reúne las monografías de algunas localidades de Ixmiquilpan que fueron visitadas entre marzo a septiembre de 2013.
KEMANDIRIAN GERAKAN CINTA SONIK (SAMPAH ORGANIK) MENGELOLA SAMPAH DARI SUMBER RUMAH TANGGA DESA LENGKONG KECAMATAN BOJONGSOANG KABUPATEN BANDUNG
Authors: Kurniawati Ratna Dian , Fauziah Diah Adni , Stellata Alyxia Gita , Munawaroh Madinatul , Oktafiani2 Hani , Setiawati Rita , Nurhaliza Farah , Hidayana Haiqal Akbar , Nugraha Mochamad Faisal
Published: March 2024

Upaya pengolahan sampah pada sumbernya merupakan suatu keharusan mengingat Tempat Pembuangan Akhir (TPA) Sarimukti hanya menerima sampah sebesar 50%. Upaya tersebut meliputi mengurangi sampah dengan metode 3R (Reduce, Reuse dan Recylce) dan mengolah sampah mandiri melalui pengomposan sederhana dari sumber masing-masing. Wilayah RT 01/013 Desa Lengkong Kecamatan Bojongsoang merupakan pemukiman padat penduduk yang telah memiliki Tempat Pengelolaan Sampah Reduce, Reuse, Recycle (TPS 3R) Kelompok Swadaya Masyarakat (KSM) Bagja sejak tahun 2021. TPS 3R ini hanya menampung sampah 3 RW (RW 5, 9, dan 13) dari total 17 RW di Desa Lengkong. Artinya keberadaan TPS 3R KSM Bagja belum dapat menampung timbulan volume sampah sehingga menjadi permasalahan kesehatan dan kesehatan lingkungan. Kondisi diperparah saat TPA Sarimukti over capacity dan mengalami kebakaran. Pengabdian masyarakat ini bertujuan untuk meningkatkan pengetahuan masyarakat terutama RT 01/013 Desa Lengkong tentang pengolahan sampah organik rumah tangga. Metode pengabdian Masyarakat yang bertema ”Gerakan Cinta Sampah OrgaNIK” (Cinta SONIK) meliputi penyuluhan, edukasi, praktik pengolahan sampah organik dan pemberian bantuan alat pengolahan sampah berupa alat pembuat biopori dan EM4 sebagai pengurai bahan organik. Awal Pengabdian masyarakat didapatkan nilai rata-rata Pretest 62,63 yaitu Sebagian besar (73.7%) peserta berpengetahuan cukup tentang pengolahan sampah organik. Setelah dilakukan edukasi tentang pengolahan sampah organik terdapat peningkatan rata-rata pengetahuan peserta menjadi 84,73. Analisa data menyatakan ada perbedaan signifikan antara pengetahuan responden sebelum dan sesudah diberikan edukasi tentang pengolahan sampah organik rumah tangga. Pengabdian Masyarakat yang telah dilakukan berhasil meningkatkan pengetahuan Masyarakat RT 01/013 Desa Lengkong.
Climate change and zoonotic diseases: a conceptual framework for predicting and managing health risks in the USA
Authors: Olumuyiwa Tolulope Ojeyinka  , Toritsemogba Tosanbami Omaghomi
Published: March 2024

The executive summary will provide a concise overview of the conceptual framework aimed at understanding the relationship between climate change and zoonotic diseases in the USA. It will highlight the significance of addressing this issue, the objectives of the framework, expected outcomes, and the proposed methodology for research and implementation. It encapsulates the essence of the proposed framework, highlighting its significance, objectives, methodology, and expected outcomes. Climate change poses a significant threat to public health, exacerbating the emergence and transmission of zoonotic diseases across the USA. This executive summary underscores the critical need for a proactive approach to understanding and managing the complex interplay between climate change and zoonotic diseases to safeguard the health of communities. The framework aims to address this pressing issue by elucidating the mechanisms through which climate change influences the dynamics of zoonotic diseases. By integrating multidisciplinary research, predictive modeling, and public health strategies, the framework seeks to enhance the nation's capacity to predict, prevent, and mitigate the health risks associated with climate change-driven zoonotic diseases. Key objectives of the framework include developing predictive models to identify high-risk areas and vulnerable populations, elucidating the pathways of disease transmission, and proposing evidence-based interventions to mitigate health risks. By fostering collaboration among researchers, policymakers, and public health practitioners, the framework aims to translate research findings into actionable strategies and policies that protect public health and promote resilience in the face of climate change. Expected outcomes of the framework include improved understanding of the complex relationship between climate change and zoonotic diseases, enhanced surveillance and early warning systems, and informed decision-making to guide public health interventions. Ultimately, the framework seeks to empower communities and decision-makers with the knowledge and tools needed to adapt to changing environmental conditions and mitigate the health impacts of zoonotic diseases in the USA.
Profile of women with Gynaecological cancers at a Tertiary Hospital in Southern Nigeria
Authors: Justina Omoikhefe Alegbeleye  , Celestine Osita John
Published: March 2024

Background: Gynaecological cancers remain a major public health concern in Low-and Middle-Income Countries. In sub-Saharan Africa, gynaecological cancers account for approximately one-third of all female cancers. Objectives: To determine the socio-demographic, reproductive, and clinical characteristics of gynaecological cancer patients at the University of Port Harcourt Teaching Hospital. Materials and Methods: This was a prospective cross-sectional study of 75 women with histologically confirmed gynaecological cancer managed at the University of Port Harcourt Teaching Hospital, from January 1, 2022, to December 31, 2022. A structured interviewer-administered questionnaire was used to obtain socio-demographic characteristics and clinical profile from the patients and their clinical records after informed consent was obtained. Data was entered into a MS Excel spreadsheet and analyzed with SPSS version 25. Results: Most 27 (36%) of the women were between 40-49 years of age, with a mean age of 50.4 ± 12.3 years. Majority 46 (61.3%) were married, 27 (36%) had tertiary education, and two-thirds earned N30,000 or less (≤ $20) per month. Many 23 (30.7%) were Para ≥ 5, almost all 63 (84%) of the women were referred to UPTH, with one-third 21 (33.3%) of the referrals coming from other tertiary health facilities. Most 63 (84%) of the women had never had a Pap smear screening, and 48 (64%) were menopausal. The most common presenting symptom was vaginal bleeding 37 (49.3%). Cervical cancer accounted for about half 40 (53.3%) of the cases, followed by ovarian cancer 27 (36%), with the majority 28 (43%) presenting with stage III disease. Chemotherapy was administered to all the patients. However, treatment was delayed in 57 (76%) of the women due to financial constraints, with most of the funding and support coming from family members in 43 (57.3%) of the women. Conclusion: There is an urgent need to increase advocacy for gynaecological cancers to increase awareness, prevent late presentation and progression of early disease. Furthermore, the government needs to subsidize the cost of cancer care to encourage early presentation and treatment.
Conceptual framework for global protection against technology-enabled violence against women and girls
Authors: Chidinma Favour Chikwe  , Nkechi Emmanuella Eneh  , Chidiogo Uzoamaka Akpuokwe
Published: March 2024

Technology-enabled violence against women and girls has emerged as a significant and complex issue in today's digital age. This form of violence, which includes cyberstalking, online harassment, and the non-consensual sharing of intimate images, poses serious threats to the safety, privacy, and well-being of women and girls worldwide. Addressing this issue requires a comprehensive and coordinated response that integrates legal, technological, and social interventions. This concept paper proposes a conceptual framework for global protection against technology-enabled violence against women and girls. The framework is based on a thorough review of existing literature, research, and best practices in the field, and aims to provide a roadmap for stakeholders to develop effective strategies and interventions to prevent and address this form of violence. The framework consists of the Legal Dimension which focuses on the legal frameworks and mechanisms needed to prevent and address technology-enabled violence against women and girls. It includes an analysis of existing laws and regulations, as well as recommendations for strengthening legal protections and ensuring accountability for perpetrators. The Technological Dimension explores the role of technology in both perpetrating and preventing violence against women and girls. It includes an examination of technological solutions, such as digital security tools and platforms, as well as ethical considerations related to technology development and use. The Social Dimension examines the social and cultural factors that contribute to technology-enabled violence against women and girls. It includes an analysis of gender norms, power dynamics, and social media dynamics that influence the prevalence and impact of this form of violence. The framework also includes strategies for implementing its recommendations at the global level, including advocacy efforts, capacity-building initiatives, and partnerships with governments, civil society organizations, and the private sector. It emphasizes the importance of multi-stakeholder collaboration in addressing this complex issue. Overall, the conceptual framework for global protection against technology-enabled violence against women and girls aims to provide a comprehensive and holistic approach to addressing this pressing global challenge. We hope that this framework will serve as a valuable resource for stakeholders working to create a safer and more inclusive digital environment for women and girls worldwide.
Antioxidant activity and phytochemical analysis of aqua-ethanol extract of Bauhinia racemosa Lam. leaves
Authors: Bhimraj Gawade
Published: March 2024

The objectives of this study were to evaluate antioxidant activity, qualitative phytochemical analysis and LC-MS/MS analyses of aqua-ethanol extract of Bauhinia racemosa Lam. plant leaves. The extract afforded the rich content of different phytochemicals reported in qualitative phytochemical analysis, LC-MS/MS spectral analysis the leaves and antioxidant activity pharmacological activity. The extract was subjected to assess their antioxidant potential using DPPH in vitro system. Using DPPH (2, 2-Diphenyl-1-picrylhydrazyl) free radical scavenging assay, the aqua-ethanol extract was found to have significant antioxidant activity with an IC50 value 42.17 ± 0.03 mg/mL. A qualitative phytochemical analysis shows that the plant leaves contains carbohydrate, protein, amino acids, glycoside, tannins, saponin, flavonoids and phenolic compounds. It is concluded that the aqua-ethanol extract of Bauhinia racemosa Lam. leaves have been strong antioxidant potential. Further study is needs for isolate and characterizes the active antioxidants, which may serve as a potential source of natural bioactive antioxidants.
Vascular malformation surgery: Case report
Authors: Achouri Essam  , El Bakkal Adil  , El Youbi samir  , Naouli Hamza  , Jiber Hamid  , Bouarhroum Abdelatif
Published: March 2024

A vascular malformation is an abnormal development of blood vessels. They might be found in the large arteries and veins, in smaller vessels called arterioles and venules, in microscopic capillaries, and/or in the lymphatic channels that carry lymphatic fluid and white blood cells outside of the arteries and veins. Treatment options can range from addressing minor (cosmetic) concerns to providing life-saving care for critical conditions. They may include one or more of the following approaches: Catheter-based techniques such as embolization; sclerotherapy, Laser therapy, Simple observation with regular follow-up visits , Surgery Herein We report the case of a 55-year-old man with a congenital vascular malformation treated surgically.
PNLD e as propostas de produção textual escrita em livros didáticos de língua portuguesa do ensino fundamental anos finais
Authors: Lessa Neta Benigna Soares , Serafim Mônica de Souza
Published: March 2024

O presente estudo tem por objetivo investigar quais mudanças o Programa Nacional do Livro Didático (PNLD) promoveu nas propostas de produção textual escrita nos livros didáticos de Língua Portuguesa do Ensino Fundamental Anos Finais nos últimos cinquenta anos. Nossa fundamentação teórica foi composta por documentos expedidos pelos órgãos oficiais e por autores que tratam da questão do ensino de produção textual escrita, tais como Bezerra (2001) e Marcuschi (2001), dentre outros. No que diz respeito aos procedimentos metodológicos, foram analisadas quatro propostas de produção textual escrita, presentes em livros didáticos anteriores e posteriores ao PNLD de 1997, época em que foram definidos critérios específicos para avaliação dos livros didáticos, tendo como base duas dimensões de análise: uma voltada para o contexto de produção dessas propostas; e outra mais focada no ensino em si. Os resultados revelaram que as propostas elaboradas antes da publicação do PNLD de 1997 eram vagas e descontextualizadas; já as propostas elaboradas após esse PNLD, preocupam-se com a finalidade do texto, especificidade do gênero, suporte, lugares preferenciais de circulação e interlocutor.
Ensaio reflexivo – O maravilhamento do bem-querer
Authors: Marujo Helena Águeda
Published: March 2024

O ensaio reflexivo intitulado “o maravilhamento do bem-querer: luzes da ciência para revigorar a humanização” escrito pela pesquisadora Helena Águeda Marujo da Universidade de Lisboa fecha o dossiê apresentando um outro letramento que nasce de um movimento emergente da psicologia positiva ocorrido no início do milénio. Essa nova abordagem científica objetiva o estudo das emoções positivas, do carácter positivo e das instituições positivas. Em diálogo com as ciências sociais e humanas vem apresentando resultados viáveis no que diz respeito às intervenções afetivas junto a crianças, jovens e adultos. Nesse sentido, vale a pena conhecer a reflexão trazida pela pesquisadora, fruto dos estudos do Programa de Pós-Graduação em Psicologia Positiva.
Feeling the Joy of Life in the Body
Authors: Dantas Périsson
Published: March 2024

The article aims to present how Bioenergetic Analysis exercises can be applied in a playful way in Child Psychotherapy. There are specificities in handling body work with children, which are: a) the understanding that patients are still in the process of ego development; b) plasticity of armor formation in this phase; c) the intention to strengthen more adaptive defense systems. As an initial theoretical review, the pioneering initiatives of body psychotherapies on child clinical psychology are discussed and a proposal for the use of bioenergetic exercises is launched, following the assumptions for the energetic mobilization of the armor rings in children, in the bottom-up sense. Finally, this article justifies the importance of training psychotherapists for specific care with children as a way of promoting health and rescuing Reich’s intention to prevent neuroses.
The Integration of Character Structure and Personality Organization
Authors: Coleman Ann
Published: March 2024

Theories of both Personality Organization (PO) and Bioenergetic Character Analysis (BA) are born from Psychoanalysis. Due to the influence of a medical model of understanding and treating mental health disorders PO and BA have been taught and developed separately. This article explains PO to the Bioenergetic audience, via the Psychodynamic Diagnostic Manual, Second Edition (PDM-2), and proposes a circumplex model for how to integrate the two theories. A psychoanalytic understanding of how people can organize their sense of self in a borderline or psychotic way is described, in contrast to a medical model of viewing borderline and psychotic experiences as discreet disorders. A concept of the self is defined and provides the basis for the integration of theories. Dynamics and traits for borderline and psychotic organization are described and contrasted so that a clinician can identify the difference between the two. A case study is presented to demonstrate how the integration of the two theories looks in practice.
Accurate hindcasting of explosive eruptions at Whakaari, New Zealand
Authors: Stix John , Miller Craig , Liu Yajing
Published: March 2024

Phreatic eruptions are small, sudden events, commonly with few precursory signals. They are driven by interactions between magmatic and hydrothermal processes at shallow levels beneath the surface. Here we show that a sequence of banded tremor events, which occurred several weeks before the 9 December 2019 eruption of Whakaari (White Island), New Zealand, can be used to hindcast this eruption. The banded tremor sequence reveals a progressively decreasing time interval between tremor bands. Extrapolating the tremor bands to a time interval of zero provides an accurate estimate, at least one week prior to the eruption, to within 10.2 hours of when the eruption would occur, with a 2.8-day range between 95 % confidence intervals. A similar set of tremor signals appeared before the 27 April 2016 eruption, and these signals provide a very accurate hindcast of this eruption to within 2.61 hours, with a 2.2-day range between 95 % confidence intervals. Our analysis indicates that this potential forecasting approach may prove useful for successfully and accurately forecasting future eruptions at Whakaari. The approach also may be applicable to other volcanoes similar to Whakaari which experience sudden phreatic and phreatomagmatic eruptions.
Pengaruh You Tube Beauty Vlogger dan Labelisasi Halal Terhadap Keputusan Pembelian Produk Scarlett Whitening
Authors: Khoiryah Putri , Amir Amri , Ridhwan Ridhwan
Published: March 2024

Tujuan – Tujuan dari penelitian ini adalah untuk mengetahui pengaruh youtube beauty vlogger dan labelisasi halal terhadap keputusan pembelian produk scarlett whitening terhadap mahsiswa ekonomi islam universitas.
Metode – Pendekatan yang digunakan dalam penelitian ini adalah metode kuantitatif dengan menggunakan metode analisa data berupa uji validitas, uji reliabilitas dan regresi linear berganda.
Hasil – Hasil penelitian menunjukkan bahwa youtube beauty vlogger dan labelisasi halal berpengaruh positif terhadap keputusan pembelian produk scarlett whitening. Hasil ini mengindikasikan bahwa dengan adanya youtube beauty vlogger dan lablisasi halal akan meningkatkan peluang mahasiswi universitas jambi dalam membeli produk scarlett whitening.
Originalitas – Penelitian ini mengungkap pengaruh youtube beauty vlogger dan label halal   terhadap keputusan pembelian produk scarlett whitening pada mahasiswi ekonomi islam universitas jambi.
Implikasi – Youtub beauty vlogger dan label halal sangat membantu mahasiswi dalam memutuskan keputusan pembelian produk scarlett whitening.
Pengaruh Profitabilitas Terhadap Harga Saham Perusahaan Perbankan BUMN
Authors: Rohmadi Rohmadi , Bagaskara Doni Yusuf , Nurbaety Eemy
Published: March 2024

Tujuan – Tujuan penelitian ini dilakukan adalah melihat perbedaan pengaruh Return on Asset (ROA), Return on Equity (ROE), dan Net Interest Margin (NIM) terhadap harga saham bank BUMN sebelum dan dimasa pandemi COVID-19
Metode – Penelitian ini menggunakan teknik analisis kuantitatif, dengan menggunakan alat Uji SPSS 2023 dan metode analisis Regresi Linier Berganda, Penelitian ini meneliti lima bank yang dimiliki oleh Badan Usaha Milik Negara (BUMN) yang terdaftar di Bursa Efek Indonesia (BEI). Periode penelitian mencakup enam tahun, meliputi periode sebelum pandemi COVID-19 (2017-2019) dan dimasa pandemi COVID-19 (2020-2022)
Hasil – Hasil penelitian menunjukkan bahwa sebelum pandemi COVID-19, ROA dan NIM memiliki pengaruh yang signifikan terhadap harga saham, sedangkan ROE tidak memiliki pengaruh yang signifikan. Sebaliknya, selama pandemi COVID-19  , ROA dan ROE memiliki pengaruh signifikan terhadap harga saham, sedangkan NIM tidak  berpengaruh yang signifikan terhadap harga saham.
Originalitas – Penelitian ini mengungkap perbedaan ROA, ROE dan NIM terhadap harga saham bank BUMN sebelum dan sesudah Covid 19.
Implikasi - Perbedaan harga saham bank BUMN sebelum dan sesudah Covid 19’ dengan melihat ROA, ROE dan NIM membentu investor dalam melakukan keputusan investasi.
Implementasi Keuangan Iknlusif Pada Lembaga Keuangan Syariah
Authors: Hasda Mifta , Mairiza Diany , Syaipudin Muhammad , Reza Saru
Published: March 2024

Tujuan – Tulisan ini membahas tentang implementasi keuangan inklusif pada lembaga keuangan syariah studi pada BMT Marwah yang berlokasi di Kabupaten Kampar.

Metode – Dalam penelitian ini metode yang digunakan adalah kualitatif dengan key informan merupakan pimpinan BMT Marwah. Untuk validasi data menggunakan metode triangulasi dengan melakukan observasi dan wawancara kepada anggota BMT Marwah.  

Hasil – Adapun hasil dari Penelitian ini menunjukkan bahwa akses untuk menjadi anggota dan menggunakan layanan jasa keuangan di BMT Marwah cukup mudah dan murah. Produk yang di berikan berbagai macam sehingga dapat dipilih sesuai dengan kebutuhan anggota. Kemudian dengan menjalankan fungsi social BMT Marwah dapat membatu masyarakat yang membutuhkan.

Implikasi – Implementasi keuangan inklusif pada BMT Marwah dapat meningkatkan kualitas ekonomi dan kesejahteraan anggot maupun masyarakat sekitar yang dapat manfaat dari fungsi sosial yang di jalankan BMT Marwah.
Video Games Should Not Be Studied as Media That Only Passively Transmit Social Information
Authors: Qiu Boyu , Zhang Wei
Published: March 2024

There is a close connection between video games and social life, and researchers are interested in whether and how video games shape aggression and prosocial behaviors. However, there are great inconsistencies across studies on this topic. These mixed results may be due in part to a focus on learning models that were relevant in research on traditional media like television but are less useful in research on video games. Unlike other media, video games are characterized by frequent game-player interactions and immediate feedback, and there is evidence that in-game rewards and punishments can shape aggressive or prosocial behavior inside and outside the game. We argue that reinforcement learning may help us to understand the effects of video games on aggressive and prosocial behaviors, and propose a conceptual model based on this argument.
A momentary assessment of the future of experience sampling research
Authors: Piccirillo Marilyn , Fritz Jessica , Cohen Zachary Daniel , Frumkin Madelyn , Kirtley Olivia J , Moeller Julia , Neubauer Andreas B. , Norris Lesley , Schuurman Noémi Katalin , Snippe Evelien , Bringmann Laura Francina
Published: March 2024

The experience sampling method (ESM) enables data collection from everyday life,improving assessment of cognitive, affective, and behavioral constructs as they vary between- and within people over time and context. However, the issues of how we best can measure constructs using ESM remains largely unknown as existing measurement theory, which was developed primarily to describe the measurement of retrospective, self-report, cross-sectional data, is misaligned with the temporally granular and contextually complex nature of ESM data. To improve research using ESM, better measures are needed, along with a measurement theory and statistical methods that address the unique features of ESM data. In this research agenda, we propose a series of i) qualitative, ii) observational, iii) experimental, and iv) meta-analytic research to advance knowledge on survey (item content, response options) and protocol design (measurement reactivity, timescales, stationarity, and missingness) for ESM research. We also discuss considerations regarding the reproducibility and generalizability of the ESM method. Results from the research proposed here can strengthen our understanding of measurement theory for ESM data, facilitating the development of best practices for ESM design and implementation, and thereby advancing future applications of ESM.
How displacement might have evolved
Authors: Zhang Elizabeth Qing , Shi Edward Ruoyang , Benítez-Burraco Antonio
Published: March 2024

Displacement is usually regarded as one of the distinctive design features of human language. Previous discussions about its evolutionary origins have focused on the possibility that the communication systems of other species show evidence of displacement. Nonetheless, as with other components of human language, tracing the evolutionary history of displacement would benefit from a bottom approach. Accordingly, in this paper, we specifically build on diverse neurobiological findings (but not only) to propose a novel evolutionary itinerary for displacement as found in language. We support the view that changes in selected brain areas (including the hippocampus, the basal ganglia, the thalamus, and the parietal cortex), in part resulting from our trend towards a more prosocial behavior (aka human self-domestication), might have potentiated our episodic memory and mental time travel abilities, in turn strengthening displacement in language and cognition.
The paper was boring and long: A reply to Michel and Löhr’s theory of predicate ordering in copredication
Authors: Murphy Elliot
Published: March 2024

In a recent publication, Michel and Löhr (2024) propose a predictive processing (PP) theory of copredication. They do so in an attempt to account for previously documented predicate ordering effects, whereby copredication acceptability is significantly impacted by the order of predicates. I review how their PP model is unfit for purpose, does not account for the empirically documented effects, does not provide novel experimental directions or conceptual innovations, and ultimately falls back on assumptions already presented in the copredication literature. Hence, the PP model fails empirically and theoretically.
The Manipulation of Top-down Interpretation as One’s Symptomatic Body Reduces the Sense of Body Ownership
Authors: Yamamoto Kazuki , Nakao Takashi
Published: March 2024

Sense of body ownership has been studied using rubber hand illusion (RHI) and full-body illusion (FBI). It has recently become clear that consciously interpreting a fake body as one’s own in a top-down manner influences these body illusions. Furthermore, a study interestingly found that the influence of top-down interpretation was moderated by the degree of depersonalization, which was a symptom of a lack of sense of body ownership. In a case study on depersonalization, the top-down interpretation of one’s body was suggested to be a negative physical state that made it difficult to feel a sense of body ownership. However, this has not been examined. We examined the influence of negative top-down interpretation using an FBI procedure. A fake body was instructed to be viewed as a negative self-body (“view the virtual body’s back while regarding the virtual body as your own experiencing abdominal pain”). To examine the influence of a negative top-down interpretation, participants were instructed to interpret the body as their own (neutral self-body) as a control condition. We used skin conductance responses to a fearful stimulus presented after an illusion procedure to measure the experienced degree of FBI. Results indicated a significant difference in the skin conductance response between the synchronous and asynchronous presentation of visual-tactile stimuli in the control condition, which confirmed the occurrence of the illusion. However, the occurrence of the illusion was not confirmed when the participants were instructed to interpret the virtual body as their own in a negative physical state, and the degree of FBI was smaller than the control condition. Our finding that a FBI was inhibited by manipulation of the top-down interpretation suggested that it could be a factor that inhibited the creation of a sense of body ownership.