bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH KEBIJAKAN PEMERINTAH TERHADAP HARGA PANGAN DI MALUKU UTARA
Authors: Rachman Sitra Anna A , Tjokrodiningrat Suryati , Sapsuha Yusri , Sjafani Nur , Sudjud Suratman , Rasulu Hamidin
Published: August 2024

The government implements a price control policy to protect producers and consumers while simultaneously reducing the rate of inflation by providing subsidies to companies that produce basic necessities and newly developing companies to reduce production costs so they can compete with imported products. The aim of this research is to analyze the influence of government policy on food prices in North Maluku (North Maluku Province, Ternate City and Central Halmahera Regency. Analyze the influence of government policy on food supply in North Maluku. And analyze the influence of government policy on people's purchasing power in North Maluku. The method used in this research is a descriptive method with a simple quantitative and qualitative approach. The research results which have been analyzed with Part Least Square (PLS), using the SmartPLS 4 application tool, show that Government Policy Intervention has a real or significant effect on Food Prices in the City. Ternate and Central Halmahera Regency, then (H1: accepted). So it can be explained that there is a direct influence of government policy intervention variables on food prices in Ternate City and Central Halmahera Regency. Government Policy Intervention has no real effect on Food Supply in Ternate City and Regency Central Halmahera has no real effect or (H0: rejected). And Government Policy Intervention has no real effect on People's Purchasing Power or (H0: rejected). In conclusion, government policy has a significant impact on food prices in the North Maluku region. For this reason, it needs to be optimized through subsidy policies, price regulation, distribution and logistics, agricultural support, and import management. The government also needs to make efforts to ensure the availability of sufficient food supplies at affordable prices for the community. With the right policies, local governments can help stabilize food prices and increase food security in the North Maluku region.Keywords: Government Policy, Food Prices, North Maluku
Análise da correlação do uso excessivo de ácido fólico na gravidez com o Transtorno do Espectro Autista (TEA)
Authors: Calça Larissa Martins , Colpo Eduarda Zimermann , Rebolo Maria Eduarda Camargo , Villa Mariana Schons , Domingos Tatiane Figueiredo Dias de Moura
Published: August 2024

O Transtorno Espectro Autista (TEA) é caracterizado por um distúrbio do neurodesenvolvimento com manifestações atípicas comportamentais, déficits na comunicação e nas interações sociais e padrões de comportamento repetitivos e estereotipados. O Ácido Fólico é um dos responsáveis pelo neurodesenvolvimento do feto durante a gestação, sua falta pode ocasionar complicações ou deficiências ao recém-nascido. Desta forma, este estudo tem como objetivo reunir artigos sobre o uso do ácido fólico durante o período gestacional e avaliar sua correlação com nascimentos de crianças com Transtorno do Espectro Autista. A estratégia de busca foi a seleção de artigos em português e inglês na base de dados PubMed, SciELO e ScienceDirect, durante o período de fevereiro a junho de 2024. Com base nos achados dos artigos selecionados, a ingestão correta do folato pode reduzir em até 70% a chance de o embrião desenvolver defeitos do tubo neural, os quais podem ocorrer em 1 a cada 1.000 gestações. Quando analisado o risco-benefício da suplementação com ácido fólico na dose correta, conclui-se que os benefícios da suplementação do ácido fólico se sobressaem aos possíveis malefícios.
Revisão sistemática sobre o autocuidado de indivíduos com Diabetes mellitus tipo 1
Authors: Lima Janaice Vitória Dias , Cardoso Neto Antonio da Costa , Magalhães Bruna Cruz , Oliveira Marcia Silva de
Published: August 2024

De acordo com a Organização Mundial da Saúde, o diabetes tipo 1 é uma condição crônica onde o pâncreas não produz insulina suficiente. Este trabalho tem como objetivo realizar uma revisão sistemática sobre a importância do autocuidado de indivíduos com diabetes mellitus tipo 1 (DM1). Trata-se de um estudo de revisão sistemática, seguindo as normas da declaração PRISMA, para responder à pergunta norteadora mencionada na introdução do presente estudo.  Foram incluídos doze trabalhos publicados nos últimos cinco anos. Os resultados deste estudo apontam que a importância do autocuidado de indivíduos com DM1 se pauta na prevenção de agravos à saúde, redução de riscos à saúde, redução de gastos dos serviços de saúde, melhoria da qualidade de vida dos pacientes e minimização de complicações de saúde. Dessa forma, recomenda-se a realização de mais estudos sobre a temática de modo a facilitar a compreensão sobre o tema e difundir melhor o conhecimento acerca do autocuidado em casos de DM1, suas barreiras e as formas como podem ocorrer o incentivo ao autocuidado, melhorando ainda a abordagem dos profissionais de saúde, o preparo de acadêmicos e a compreensão da comunidade sobre o assunto.
The Ember Months: A Dark Time for Road Safety in Nigeria?
Authors: Wole Morenikeji , Musa Haruna (D.) , Shareefdeen Akande (O.) , Lanke Owoeye , Sikiru Balogun
Published: August 2024

Road Traffic Crashes (RTC) are known to exhibit various trends which are attributed to various factors such as the climatic seasonal changes and particular time periods, such as ember months (September, October, November, and December). This study explored the potential interaction between ember months and seasons concerning crash rates. Data on crash rates for 96 months (January 2014-December 2021) were extracted from the records at the Federal Road Safety Corps (FRSC), Headquarters Office, Abuja, and the dataset was organised based on the two independent variables: ember months and seasons (Wet/Dry). A two-way ANOVA was performed to analyse the main effects of both factors and examine whether there was an interaction effect between them. The results of the two-way ANOVA showed no significant interaction effect between ember months and seasons regarding traffic crash rates. However, significant main effects were observed for season (Wet/Dry) but with no significant main effect for specific months (Ember/non Ember). It was concluded that season has a statistically significant impact on crash rates, while ember months do not show a significant influence on crash rates. While the number of crashes does not appear to be significantly affected by the ember months, it is recommended that it is still important the Federal Road Safety Corps consistently enforce traffic laws and road safety measures all year long to maintain standards of safety.
THE RELATIONSHIP BETWEEN ORGANIZATIONAL CULTURE AND COMMITMENT TO ORGANIZATION CITIZENSHIP BEHAVIOR AT PRESTISA (PT KAYA RAYA TURUN TEMURUN)
Authors: Naiborhu Joseph Rivan , Anggraini Nenny
Published: August 2024

Organizational Citizenship Behavior (OCB) is prosocial behavior or extra precautions that  exeed a specified discription of the role within the organization or company. In this study, the issues to be discussed is how is the relationship between organizational culture, organizational commitment, and Organizational Citizenship Behavior. The research was conducted at the PT PRESTISA, Jakarta. The purpose of this study was to determine the relationship of organizational culture and organizational commitment of Organizational Citizenship Behavior (OCB). This research is descriptive-correlational by as many as 30 employees, and data were analyzed using Spearmen Rank Correlation and multiple correlation Pearson Product Moment. The result of this study was indicated that 1) there is a positive and significant relationship between Organizational Culture and OCB of employees at PT PRESTISA. It is shown by t (3,348) is greater than t table (2,048), 2) there is a positiveand significant relationship between Organizational Commitment and OCB  of empoyees at PT PRESTISA. It is shown by t (2,483) is greater than table (2,048), 3) there is a positive and significant relationship between Organizational Culture, Organizational Commitment, and OCB of employees at PT PRESTISA. It is shown by F (7,958) is greater than F table (3,354). 
Keyword : organizational culture, organizational commitment, organizational citizenship behavior (OCB)
ANALYSIS OF THE INFLUENCE OF BUSSINESS RISK AND FINANCIAL RISK AGAINST THE PROFITABILITY OF TELECOMMUNICATIONS SUB SECTOR COMPANIES LISTED ON THE INDONESIA STOCK EXCHANGE (2012-2019 PERIOD)
Authors: Sondang  , Ganda T.  Hutapea
Published: August 2024

This research aimed to analyze the influence of business risk and financial risk both partially and simultaneously against Return on Equity of telecommunications companies listed on the Indonesia Stock Exchange during 2012-2019 period. The samples in this study were 4 telecommunications companies, which publishes the annual report during 2012-2019 period. Analysis teqnique used is multiple linear regression. The result of these findings of t test shown that business risk partially has no effect against Return on Equity, based on the findings shown that a significant value of 0.561>0.05 and financial risk has effect against Return on Equity, based on the findings shows that a significant value of 0.023<0.05. The findings state that business risk and financial risk simultaneously have no effect against Return on Equity, this is shown that a significance value (0.062>0.05). The result of data shown that the coefficients of determination is 0,174 or 17,4%.
 Keywords: Business Risk, Financial Risk, Profitability
COST-VOLUME-PROFIT ANALYSIS AS A TOOL FOR EVALUATING THE ACHIEVEMENT OF PROFIT ON GULAKU PRODUCT IN MINI MARKET PRIMER KOPERASI MARKAS BESAR ANGKATAN UDARA BEFORE AND DURING COVID-19 PANDEMIC
Authors: Laura Magdalena Tampubolon  , Juaniva Sidharta  , Lumbantoruan Rutman
Published: August 2024

The COVID-19 pandemic has the potential to result in losses on profit achievement, including Gulaku products at the Mini Market Primer Koperasi Markas Besar Angkatan Udara  (Mini Market Primkopau), especially when the emergence of this virus in early 2020. Good profit achievement is evaluated not only from the nominal profit alone, but using tools such as cost-volume-profit analysis, namely the break-even point and safety limit. Therefore, this study aims to determine profit achievement, find out cost-volume-profit analysis, and find out the results of cost-volume-profit analysis as an evaluation tool for achieving profit on Gulaku Products at the Mini Market Primer Koperasi Markas Besar Angkatan Udara  Before and During the COVID-19 Pandemic. The research focused on the differentiation of Gulaku Hijau and Gulaku Kuning products in the research period before and during COVID-19, namely 2019, 2020, and 2021. Based on the evaluation that has been carried out, it can be seen that the COVID-19 pandemic has affected the profit achievement of Gulaku products in the Mini Market Primkopau. Despite experiencing a decline in profit achievement in 2020, Primkopau still managed to break even. In addition to the COVID-19 pandemic, it turns out that other behaviors have an influence on the achievement of Gulaku product profits, namely large demand switching to Gulaku Kuning which causes a significant decrease in the achievement of Gulaku Hijau profits and a significant increase in the Gulaku Kuning profit achievement followed by the product mix in 2021
Keywords : CVP Analysis, profit achievement, COVID-19
STRATEGI PEMASARAN MENGGUNAKAN STORYTELLING CERITA LEGENDA PADA SITUS TOBA KALDERA: PUSUK BUHIT SEBAGAI TEMPAT AWAL MUASAL SUKU BATAK
Authors: Posma Sariguna Johnson Kennedy1,  , Suzanna Josephine Tobing 2  , Lumbantoruan 3 Rutman , Ricky Martin Manullang 4
Published: August 2024

This paper describes the importance of storytelling as an effective marketing strategy for tourism promotion. A captivating story can make a tourist destination come alive and attract visitors to learn more about it. Additionally, local wisdom and legends, part of a culture's heritage, should be preserved and used to promote tourism. Specifically, this paper explores the narratives and legends of Pusuk Buhit, a destination in the Toba Caldera UNESCO Global Geopark in Samosir, North Sumatra, Indonesia. The qualitative method is used to interpret the data collected from the field. The study highlights the importance of preserving local wisdom and legends to promote tourism and preserve cultural heritage.
Keywords: Marketing Strategy, Storytelling, Toba Caldera, Pusuk Buhit, Batak Tribe
DAMPAK PERANG RUSIA-UKRAINA TERHADAP PEREKONOMIAN GLOBAL
Authors: Johnson Kennedy Posma Sariguna
Published: August 2024

Geopolitical events, such as the Russia-Ukraine conflict, have a significant impact on global commodity, financial, and capital markets. This conflict creates uncertainty that can influence investor sentiment, stock prices, trade activities, and the broader economy. The study employs a qualitative approach to examine the impact of the Russia-Ukraine conflict on the global economy. The research findings reveal an increase in global commodity prices, financial market fluctuations, and capital market volatility, with varying effects across different sectors. Additionally, the conflict affects the Indonesian economy, particularly concerning oil imports and the exchange rate of the rupiah. With the growing geopolitical uncertainty, a better understanding of its impact becomes crucial for making informed decisions in the global market. This research provides value in identifying risks and opportunities and assists stakeholders in making sound decisions amid emerging geopolitical risks.Keywords: Russia-Ukraine War, Global Economy, Geopolitical Ris
Upaya Pencegahan Patologi Birokrasi Melalui Penerapan Good Government untuk Menciptakan Birokrasi yang Efisien
Authors: Ponto Iriane Sosiawaty , Patty Julia Theresia , Sakir Ahmad Rosandi
Published: August 2024

Birokrasi merupakan instrumen penting dalam masyarakat yang keberadaannya diakui secara hukum dan diatur oleh perundang-undangan. Proses yang panjang dan birokratis sering kali dianggap sebagai hambatan dalam memberikan pelayanan yang cepat dan efisien, sehingga mempengaruhi kepuasan masyarakat terhadap layanan publik. birokrasi yang sakit atau patologi birokrasi menjadi istilah yang menggambarkan kondisi buruk yang dihadapi oleh birokrasi di Indonesia. Jenis penelitian yang diterapkan dalam studi ini adalah penelitian dengan pendekatan kualitatif. Untuk memperoleh data, peneliti menggunakan teknik pengumpulan data berupa penelitian pustaka (library research). Dalam metode ini, data yang dicari dan dikumpulkan berasal dari kajian pustaka, termasuk buku-buku dan sumber kepustakaan lainnya yang relevan dengan topik pembahasan. Upaya untuk mengatasi patologi birokrasi meliputi reformasi administrasi publik, implementasi good governance, penguatan etika dan moralitas, pelatihan dan pengembangan keterampilan, serta partisipasi aktif masyarakat dalam pengawasan birokrasi. Langkah-langkah ini diharapkan dapat menciptakan birokrasi yang lebih transparan, akuntabel, dan responsif terhadap kebutuhan masyarakat. Penerapan prinsip good governance seperti partisipasi publik, peran hukum yang kuat, dan transparansi informasi adalah kunci untuk merubah budaya birokrasi yang rentan terhadap patologi. Dengan mengintegrasikan pendekatan ini, diharapkan birokrasi dapat berfungsi lebih efisien dan melayani masyarakat dengan lebih baik.
Biosphere, hydrosphere and noosphere as components of the hypercomplex system of planet Earth. Part 2. Biosphere as a system: a system approach in the study and representation of the biosphere
Authors: Kamnev Alexander N.
Published: August 2024

This part of the analytical review considers the biosphere as the unique, living, ecological, complex, Earth system (ESS), as a complex, hypercomplex, and adaptive system, as a hyperobject and a object of representation. The contribution by K. Linnaeus, A.A. Bogdanov, J. Lovelock, E. Morin, T. Morton and other thinkers for system approach is described.
Composition and quantitative indicators of meiobenthos in springs of Kazan and its environs
Authors: Berdnik Sergey V. , Tokinova Rimma P. , Galiahmetova Lyuciya K.
Published: August 2024

Data are presented on the hydrochemical parameters and taxonomic composition of invertebrates from nine springs located on the territory of Kazan and the Vysokogorsky district of the Republic of Tatarstan, based on studies carried out in 2018 and 2020. Representatives of 10 groups of invertebrates were found in the spring communities of meiobenthos: Nematoda (38 species and taxa of supraspecific rank), Platyhelminthes (4), Harpacticoida (4), Ostracoda (4), Cyclopoida (1), Rotifera (1), Tardigrada (1) (eumeiobenthos), and also Inseсta (4), Oligochaeta (2) and Aphanoneura (1) (pseudomeiobenthos). On sandy and silty-sandy substrates, the abundance of spring communities varies widely, from 239 to 7942 ind./dm2 in density and from 0,41 to 65,40 mg/dm2 in biomass. The leading group of meiobenthos in springs, both in terms of abundance and diversity of species, are nematodes. In rheocrene springs, chironomid larvae are also dominant in the density of organisms. A feature of the meiobenthos of geocrene springs is the absence of crustacean hydrobiont groups in its composition and the dominance of phytoparasitic and soil forms of nematodes of the order Rhabditida.
Formulasi Sediaan Krim Tabir Surya Fraksi N-Butanol Kulit Batang Rambutan (Nephelium lappaceum L.)
Authors: Sari Tisa Mandala , Agustin Diana , Fatma Yuli
Published: August 2024

Paparan sinar UV dapat menimbulkan kerusakan pada kulit sehingga dibutuhkan tabir surya untuk dapat mencegahnya. Kulit batang rambutan diketahui mengandung senyawa flavonoid yang dapat meredam efek buruk dari paparan sinar UV. Tujuan dari penelitian ini membuat formulasi sediaan krim tabir surya fraksi n-butanol kulit batang rambutan (Nephelium lappaceum L.). Penelitian ini dilakukan secara eksperimental. Fraksi n-butanol diperoleh dari hasil fraksinasi ekstrak etanol yang diekstraksi menggunakan metode maserasi. Fraksi dievaluasi sehingga diperoleh rendemen, kadar abu, dan kandungan senyawa metabolit sekunder. Formula krim tabir surya fraksi n-butanol kulit batang rambutan yaitu F0 (tanpa fraksi), F1 (1%), F2 (1,5%) dan F3 (2%). Hasil evaluasi ekstrak diperoleh rendemen sebesar 13,17%, kadar abu 0,49% dan positif mengandung flavonoid, fenolik dan saponin. Evaluasi sediaan meliputi uji organoleptis dimana masing-masing formula berbentuk setengah padat memiliki bau khas sedangkan pada warna, F0 berwarna putih, F1 berwarna pink muda, F2 berwarna pink sedang dan F3 berwarna pink pekat. Pada uji homogen semua formula menunjukkan tekstur yang homogen. Uji pH pada F0 sebesar 6,81; F1 sebesar 6,76; F2 sebesar 6,77; F3 sebesar 6,81. Semua formula termasuk tipe krim M/A. Uji viskositas menujukkan F0 (4148= cP), F1 (4374 cP), F2 (4527 cP), F3 (4940 cP). Uji stabilitas pada setiap formula menunjukkan hasil yang stabil. Uji iritasi pada setiap formula menunjukkan tidak terjadi eritema dan edema. Berdasarkan evaluasi yang dilakukan, maka formula yang diperoleh memenuhi syarat dalam pembuatan sediaan krim.
KETERKAITAN BONUS DEMOGRAFI DENGAN TEORI GENERASI
Authors: Lubis Bertha , Mulianingsih Sunasih
Published: August 2024

ABSTRAK
Kajian ini bertunjuan memberikan gambaran bahwa fenomena bonus demografi yang terjadi pada rentang waktu 2010 – 2025 akan berdampak besar terhadap kondisi kehidupan manusia di planet bumi ini. Teori generasi Strauss-Howe, memberikan gambaran munculnya generasi Alfa yang akan berdampak luas terhadap kondisi kehidupan manusia pada umumnya. Dengan menggunakan kajian pustaka yang dikumpulkan dari berbagai sumber baik dalam jejaring (online) maupun di luar jejaring (offline), dilengkapi dengan wawancara dan diskusi dengan pihak terkait, diperoleh gambaran yang lebih memadai. Hasilnya menunjukkan bahwa teori gernerasi Strauss-Howe, selama ini dipercaya menjadi acuan bagi munculnya generasi-generasi sesuai rentang waktu yang memberikan ciri-ciri tertentu, semakin hari semakin menunjukkan kemajuan dan perkembangan teknologi yang luar biasa dahsyatnya.
Kata kunci: bonus demografi, dampak, strauss-howe, teori generasi.
 
ABSTRACT
This study shows that the demographic bonus phenomenon that occurred in the period 2010-2025 will have a major impact on the conditions of human life on this planet. Strauss-Howe's generation theory provides an overview of the emergence of the Alfa generation that will have a broad impact on the conditions of human life in general. By using literature reviews collected from various sources both online and offline, equipped with interviews and discussions with related parties, a more adequate picture is obtained. The results show that Strauss-Howe's gerneration theory, has been believed to be a reference for the emergence of generations according to the timeframe that gives certain characteristics, increasingly shows the extraordinary progress and development of technology.
Keywords: demographic bonus, generation theory, impact, strauss-howe.
PELAKSANAAN PENDAFTARAN PENDUDUK OLEH DINAS KEPENDUDUKAN DAN PENCATATAN SIPIL DI KOTA PADANG
Authors: Mulya Hadyan , Irena Devi
Published: August 2024

ABSTRAK
Tujuan dari tulisan ini adalah mengetahui bagaimana pelaksanaan pendaftaran penduduk, faktor apa yang mempengaruhi serta upaya yang dilakukan pemerintah dalam mengatasi persoalan pendaftaran penduduk di Kota Padang. Metode kajian yang digunakan deskriptif kualitatif dengan pendekatan induktif. Pengumpulan data dan informasi dilakukan dengan cara observasi, wawancara dan dokumentasi. Untuk teknik analisis data dilakukan dengan reduksi data, penyajian data dan penarikan kesimpulan.
Kesimpulan yang didapatkan bahwasanya pelaksanaan pendaftaran penduduk oleh dinas kependudukan dan pencatatan sipil di Kota Padang belum sepenuhnya berjalan lancar. faktor yang mendukung lokasi kantor, keadaan sosial masyarakat, dan akses transportasi dan faktor yang menghambat sarana dan prasarana yang belum memadai, sumber daya manusia terbatas, kurangnya sosialisasi kepada masyarakat. Upaya yang dilakukan Dians Kependudukan dan Pencatatan Sipil Kota Padang untuk mengatasi persoalan pendaftaran penduduk ini dengan memaksimalkan sarana dan prasarana yang dimiliki, menciptakan inovasi baru, dan meningkatkan sosialisasi kepada masyarakat.
Kata Kunci: Pelaksanaan, Pendaftaran, Penduduk
 
ABSTRACT
The purpose of this research is to knowing how the implementation of civil population registration, the affect factor and the efforts that government do to solve the problems of civil population registration in Padang city. The method is quantitative descriptive with inductive approach. The information and data accumulation do by using observation, interview and documentation. The data analysis technic is data reduction, data presentation and conclusion. The conclusion is the implantation of civil population registration in Padang city does not good enough. The support factors are the office location, the condition of local people and transportation access. The inhibiting factors are the infrastructure and facility is not satisfy enough. limited human resources, lack of socialization to the community. Efforts made by the department of population and civil registration in the Padang city overcome the problem of population registration by maximizing the facilities and infrastructure owned, creating new innovations, and increasing socialization to the community.
Keywords: Implementation, Registration, Population
IMPLEMENTASI KEBIJAKAN PELAYANAN ADMINISTRASI KEPENDUDUKAN PADA DINAS KEPENDUDUKAN DAN CATATAN SIPIL KABUPATEN GARUT
Authors: Ismail MGS , Ismail Ismail
Published: August 2024

Kebijakan pelayanan yang dilakukan Dinas Kependudukan dan Pencatatan Sipil Kabupaten Garut, untuk mengurus dokumen kependudukan, diprlukan adanya kebijakan-kebijakan dalam implementasinya, agar masyarakat merasakan kemudahan-kemudahan didalam menerima atau mendapatkan pelayanan dari jajaran aparatur Dinas Kependudukan dan Pencatatan Sipil Kabupaten Garut. Tujuan dari penelitian ini adalah seberapa jauh kebijakan pelayanan dokumen kependudukan dan pencatatan sipil yang dilakukan oleh jajaran aparatur Dinas Kependudukan dan Pencatatan Sipil. Penelitian ini menggunakan metode penelitian kualitatif, deskriptif dengan pendekatan induktif, sumberdata diperoleh dari data sekunder dan data primer. Data Primer diperoleh dari hasil observasi kelapangan secara langsung, dengan melakukan pemetaan dan melakukan wawancara dengan para responden dilapangan. Sedangkan data sekunder didapat dari data dokumentasi, kajian -kajian pustaka, peraturan-peraturan serta jurnal-jurnal ilmiah sebelumnya. Hasil dan simpulan, bahwa kebijakan pelayanan dokumen kependudukan dan pencatatan sipil yang dilakukan oleh jajaran Dinas Kependudukan dan Pencatatan Sipil, berjalan dengan baik, dan masyarakat merasakan kepuasaan didalam menerima pelayanan yang dilakukan oleh jajaran Dinas Kependudukan dan Pencatatan Sipil Kabupaten Garut. Peran Dinas Kependudukan dan Pencatatan Sipil Kabupaten Garut, sebagai Dinas yang memiliki kewenangan dan bertanggungjawab atas pelayanan dokumen kependudukan dan pencatatan sipil, diperankan sangat baik dan penuh tanggungjawab. Kendala-kendala yang timbul disaat pelaksanaan, dilakukan dan diatasi dengan cepat oleh jajaran aparatur, sehingga masyarakat tidak terlalu lama menunggu hasilnya.
Kata kunci: Implementasi kebijakan, pelayanan, dokumen Dukcapil.
The conflict of characters in novel Sumbang by Musa Ismail (a study of Literary Psychology) and its implications for learning in schools
Authors: Mulziani
Published: August 2024

This article describes the conflict of characters in the novel Sumbang by Musa Ismail and its implications in learning in schools This type of research is qualitative research using descriptive methods of analysis. The purpose of this study is to describe the author's views on the social conflicts that occur in the novel Sumbang and its implications for learning in schools. The data collection techniques used are documentation, interview, record and record techniques. The source of this research data is a novel with the title Sumbang and the subject of the informant, namely Mr. Musa Ismail as the author of the novel Sumbang. The results showed that there is an author's view of character conflicts, namely, character conflicts between individuals and individuals and individuals with society or groups.
Balinese Phonological Interference in Indonesian Communication in The Panglipuran Village
Authors: Dea Putri Pascha  , Mikail Randu R.  , Tasya Febrianty  , Nurmalita Herdiana  , Endang Sholihatin
Published: August 2024

This study aims to (1) know the Balinese language interference that affects the spoken pronunciation of Indonesian in Panglipuran village community and (2) Know the factors that cause Balinese Language Interference to Indonesian. This research uses qualitative research methods, data collection is done through direct interviews to data sources, namely the people of Panglipuran Village Bali. The results of this study show that, phonological interference is influenced by several phonological processes in the form of phoneme changes such as, changes in phoneme /e/ to phoneme /a/, changes in consonant phoneme /b/ to consonant phoneme /m/, changes in phoneme /e/ to phoneme /i/, changes in phoneme /a/ to phoneme /o/, changes in phoneme /e/ to phoneme /i/. Then there is the diphthong process as in the phoneme /au/ into the phoneme /o/, there is also the metathesis of the phoneme /o/ which moves to the phoneme /e/, the elision of the middle phoneme /a/, and the influence of the speaker's hypercorrection. Language interference can also be influenced by several factors such as, 1) speakers who are bilingual; 2) Balinese and Indonesian are cognate languages and; 3) the influence of the times and environmental factors.
The Right to Protect, not the Responsibility to Protect, in Africa
Authors: Ifediora Obinna
Published: August 2024

Studies on the use of force have subsumed the right of intervention under Article 4(h) of the Constitutive Act of the African Union (AU) under the responsibility to protect (R2P). The approach reflects a commitment to the international security concept of global multilateralism. The puzzle is that the approach does not account for official AU policy objecting to R2P, as revealed in the Ezulwini Consensus, presentations by AU officials, and AU communiqués rejecting the UN Security Council-authorized use of force in Libya. This study embraces the international security concept of regional multilateralism and conceptualizes Article 4(h) as the right to protect concept: the distinct Africa-engineered security model of using force to prevent genocide and atrocity crimes. Official records show the right to protect conveys a unique African rationale: a bold legal structure sustaining African primacy on the use of force for genocide and atrocity crimes prevention in the international system.
Integrated cellular 4D-TIMS lipidomics and transcriptomics for characterization of anti-inflammatory and anti-atherosclerotic phenotype of MyD88-KO macrophages
Authors: del Barrio Calvo Carla , Bindila Laura
Published: August 2024

Introduction: Recent progress in cell isolation technologies and high-end omic technologies has allowed investigation of single cell sets across multiple omic domains and a thorough exploration of cellular function and various functional stages. While most multi-omic studies focused on dual RNA and protein analysis of single cell population, it is crucial to include lipid and metabolite profiling to comprehensively elucidate molecular mechanisms and pathways governing cell function, as well as phenotype at different functional stages.

Methods: To address this gap, a cellular lipidomics and transcriptomics phenotyping approach employing simultaneous extraction of lipids, metabolites, and RNA from single cell populations combined with untargeted cellular 4 dimensional (4D)-lipidomics profiling along with RNA sequencing was developed to enable comprehensive multi-omic molecular profiling from the lowest possible number of cells. Reference cell models were utilized to determine the minimum number of cells required for this multi-omics analysis. To demonstrate the feasibility of higher resolution cellular multi-omics in early-stage identification of cellular phenotype changes in pathological and physiological conditions we implemented this approach for phenotyping of macrophages in two different activation stages: MyD88-knockout macrophages as a cellular model for atherosclerosis protection, and wild type macrophages.

Results and Discussion: This multi-omic study enabled the determination of the lipid content remodeling in macrophages with anti-inflammatory and atherosclerotic protective function acquired by MyD88-KO, hence expedites the understanding of the molecular mechanisms behind immune cells effector functionality and of possible molecular targets for therapeutic intervention. An enriched functional role of phosphatidylcholine and plasmenyl/plasmalogens was shown here to accompany genetic changes underlying macrophages acquisition of anti-inflammatory function, finding that can serve as reference for macrophages reprogramming studies and for general immune and inflammation response to diseases.
Investigating cutaneous tuberculosis and nontuberculous mycobacterial infections in a Department of Dermatology, Beijing, China: a comprehensive clinicopathological analysis
Authors: Wang Xin-Yu , Jia Qian-Nan , Li Jun , Zheng He-Yi
Published: August 2024

Background

Cutaneous tuberculosis (CTB) and nontuberculous mycobacteria (NTM) infections present considerable diagnostic and therapeutic challenges. This study aims to provide a comprehensive clinicopathological analysis of CTB and NTM infections.

Methods

We conducted a retrospective analysis of 103 patients diagnosed with cutaneous tuberculosis (CTB) and nontuberculous mycobacteria (NTM) infections at a Beijing dermatology department from January 2000 to January 2024. Demographic, clinical, histological, and laboratory finding data were collected. Diagnostic methods and histopathological examination were recorded. Treatment regimens and outcomes were reviewed. Descriptive statistics were used to summarize demographic and clinical data, and continuous variables expressed as means and standard deviations (SD), and categorical variables as frequencies and percentages. Statistical analyses were conducted using SPSS version 25.0.

Results

The cohort included 103 patients (40.8% males and 59.2% females), with a mean age of 51.86 years. Common clinical manifestations included nodules (97.1%), erythema (74.8%), and plaques (68.9%). Histological examination revealed hyperkeratosis (68.9%), parakeratosis (23.3%), and extensive neutrophil infiltration (95.1%) were observed. Acid fast bacteria (AFB) stains and nucleic acid tests exhibited respective positivity rates of 39.6% and 52.3%, respectively. Most patients were treated with a combination of three drugs; 77.1% of patients showed improvement, with the cure rate for CTB being 20.0%.

Discussion

This study highlights the diverse clinical and histological presentations of CTB and NTM infections, emphasizing the need for comprehensive diagnostic approaches. The variability in treatment regimens reflects the complex management of these infections.

Conclusion

The implementation of advanced molecular techniques and standardized treatment protocols is imperative for enhancing diagnostic precision and therapeutic outcomes.
Experimental study on dynamic interaction between ground fissure and diagonal three-section subway tunnels
Authors: Liu Lei , Ren Zhilin , Peng Weiheng , Yan Jinkai
Published: August 2024

Ground fissures, as a typical geohazard, pose potential georisks to the construction and maintenance of urban transportation infrastructure. Under the influence of ground fissures, the segmented tunnel structure used in subway systems complicates the propagation of subway train vibrations. In this study, the soil acceleration, earth pressure and contact pressure of a three-section subway tunnel under dynamic loading of a subway train in a ground fissure environment were observed and analyzed by physical modeling tests, and the effects of the presence and activity of the ground fissure and tunnel segmentation were discussed. The results show that the vibration generated by the subway traveling will have different degrees of attenuation when propagating in all directions in the soil layer, and the ground fissure has a damping effect on the subway vibration. The attenuation and enhancement of acceleration by ground fissure is affected by the activity and propagation direction of ground fissure. The distribution of additional earth pressure is affected by the ground fissure, soil contact state, which is related to the ground fissure activity state. The ground fissure activity on the contact additional pressure mainly focuses on the bottom and top of the tunnel and there are differences in the location of the hanging wall and footwall. Three-section tunnels have a stronger vibration response and vibration attenuation than monolithic tunnels due to the influence of segmentation. Based on the consideration of the effects of ground fissure and tunnel segmentation, the tunnel design mainly takes into account the amount of ground fissure activity and determines the structural measures, the tunnel structure at the location of the ground fissure is strengthened, in addition to the vibration attenuation measures for the segmented tunnels when crossing the ground fissure. The discussion of mechanical response and design measures in this study helps to reduce the georisk of ground fissures on urban underground transportation infrastructure.
Teacher-student relationship as resilience strengthener in novice teachers before and during the pandemic
Authors: Villalobos Vergara Paula , Peña-Sandoval César , Díaz Romina , Barría-Herrera Pamela
Published: August 2024

This article addresses the role of teacher-student relationship in novice teachers’ resilience before (11 participants) and during the COVID-19 pandemic (14 participants). Employing a qualitative multi-case study, we conducted a total of 35 semi-structured interviews with these 25 novice teachers working in highly vulnerable schools in the Metropolitan Region of Chile. Drawing upon the literature on teacher resilience and the teacher-student relationship, we carried out a comparative analysis of the two groups. The findings reveal two significant connections and one tension: a positive connection between the student figure and the resilient novice teachers’ identity; another positive connection between professional identity and the pedagogical relationship prioritized by resilient teachers; and a tension between the pedagogical relationship prioritized by resilient novice teachers and school leadership teams’ definition of pedagogical work. These findings show how the teacher-student relationship represents the driving force of novice teachers’ pedagogical work and resilience, an essential element that persists despite the abrupt changes generated by the pandemic. Implications highlight the significance of conducting further research on relational aspects of novice teachers’ resilience and strengthening it through institutional support systems.
Differential association of abdominal, liver, and epicardial adiposity with anthropometry, diabetes, and cardiac remodeling in Asians
Authors: Lee Vivian , Han Yiying , Toh Desiree-Faye , Bryant Jennifer A. , Boubertakh Redha , Le Thu-Thao , Chin Calvin W. L.
Published: August 2024

Background

Heterogenous deposition and homeostasis roles of physiologic and ectopic adipose tissues underscore the impact of fat compartmentalization on cardiometabolic risk. We aimed to characterize the distribution of abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), epicardial adipose tissue (EAT), and liver fat on magnetic resonance imaging (MRI), and evaluate their associations with anthropometric indices and adverse cardiac remodeling.

Methods

In this cross-sectional observational study, 149 Asian adults (57.0 ± 12.8 years; 65% males) with at least one cardiometabolic risk factor underwent multiparametric fat and cardiovascular MRI. Anthropometric indices included body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), and bioimpedance body fat mass (BFM). Associations between fat depots and anthropometric measures as well as cardiac remodeling features were examined as a single cohort and stratified by type 2 diabetes mellitus (T2DM) status.

Results

VAT and SAT had opposing associations with liver fat and EAT. Therefore the VAT/SAT ratio was explored as an integrated marker of visceral adiposity. VAT/SAT was positively associated with EAT (β=0.35, P<0.001) and liver fat (β=0.32, P=0.003) independent of confounders. Of the anthropometric measurements assessed, only WHR was independently associated with VAT/SAT (β=0.17, P=0.021). Individuals with T2DM had higher VAT and lower SAT compared to those without T2DM, translating to a significantly higher VAT/SAT ratio. EAT volume was independently associated with adverse features of cardiac remodeling: increased left ventricular (LV) mass (β=0.24, P=0.005), larger myocyte volume (β=0.26, P=0.001), increased myocardial fibrosis (β=0.19, P=0.023), higher concentricity (β=0.18, P=0.035), and elevated wall stress (β=−0.18, P=0.023).

Conclusion

Multiparametric MRI revealed abdominal VAT and SAT have differential associations with anthropometric indices and ectopic fats in a single cohort of Asians at risk of cardiometabolic disease. People with T2DM have expanded VAT and diminished SAT, endorsing the VAT/SAT ratio beyond usual anthropometric measurements as a marker for multiorgan visceral fat composition. Among the fat depots examined, EAT is uniquely associated with adverse cardiac remodeling, suggesting its distinctive cardiometabolic properties and implications.
A Succinct review of strengths, weaknesses, opportunities, and threats (SWOT) analyses, challenges and prospects of solar and wind tree technologies for hybrid power generation
Authors: Mohanaravi Kumaresen , Samykano Mahendran , Pandey Adarsh Kumar , Noor Muhamad Mat , Kadirgama Kumaran
Published: August 2024

Introduction

The increasing global demand for sustainable energy solutions highlights the urgency of exploring renewable resources, particularly sunlight, which is abundant and virtually limitless. This study reviews innovative technologies like solar trees, wind trees, and hybrid solar-wind trees, which are emerging as efficient structures for harnessing renewable energy.

Methods

A comprehensive SWOT analysis was conducted to evaluate the strengths, weaknesses, opportunities, and threats associated with solar, wind, and hybrid trees. The analysis also considered sustainability aspects, focusing on the efficiency and practicality of these technologies in various settings.

Results

Solar trees mimic natural foliage, utilizing solar modules to convert sunlight into electricity, while wind trees incorporate micro-wind turbines and solar panels, effectively harnessing both wind and solar energy. Hybrid solar-wind trees combine these technologies to provide a consistent energy supply. These structures are compact, cost-effective, and adaptable to urban landscapes.

Discussion

Challenges such as land use, aesthetic considerations, and public perception were identified. The review emphasizes the need for future research to optimize configurations and address these challenges, ensuring the successful integration of these technologies into sustainable urban landscapes.

Conclusion

This review provides critical insights for renewable energy researchers, particularly in the development of hybrid wind and solar power systems, promoting energy security and climate resilience.
From wild to mild and back again: envisioning a new model of crop improvement strategies
Authors: Pratt Richard C. , Kantar Michael Benjamin , Fumia Nathan , Nankar Amol N.
Published: August 2024

Climate change creates a leverage point in plant breeding. We must rethink the way we employ plant breeding, utilize genetic diversity, and prioritize edible plant production across the landscape. A long-term strategy to ‘redirect’ the process of crop domestication that prioritizes the generation of abiotic and biotic stress-tolerant cultivars is needed. A proposed neo-domestication strategy is presented as a case study. It entails the re-domestication of chile by retro-crossing of modern plant cultivars with landraces and a desert-adapted wild relative. An organized, collaborative effort could reintroduce stress tolerance genes that will render new cultivars more tolerant to challenges imposed by climate change. Purposeful populations generated using a broad spectrum of genetic diversity could also provide the basis for an evolutionary–participatory plant breeding process. The process must recognize the need for a paradigm shift in our resource allocation and breeding strategies. To succeed, a shared vision for neo-domestication of chile must recognize the importance of human cultural values and the need for sustained cooperation among stakeholders.
Exploring the efficacy of laser speckle contrast imaging in the stratified diagnosis of rosacea: a quantitative analysis of facial blood flow dynamics across varied regions
Authors: Liao Jin-Feng , Jiang Xue-Mei , Xie Zhen , Lei Hua , Luo Juan , Lv Yu , Liu Gang , Mao Yujie , Song Si-Yuan , Wang Yi
Published: August 2024

Background

Rosacea has a high incidence, significantly impacts quality of life, and lacks sufficient diagnostic techniques. This study aimed to investigate the feasibility of laser speckle contrast imaging (LSCI) for measuring facial blood perfusion in patients with rosacea and to identify differences in blood flow among various facial regions associated with different rosacea subtypes.

Methods

From June to December 2023, 45 patients were recruited, with 9 excluded, leaving 36 subjects: 12 with erythematotelangiectatic rosacea (ETR), 12 with papulopustular rosacea (PPR), and 12 healthy controls. The Think View multispectral imaging analyzer assessed inflammation via gray reading values across the full face and five facial areas: forehead, nose, cheeks, and chin. LSCI measured and analyzed blood perfusion in the same areas. Plasma biomarkers interleukin-6 (IL-6), IL-1β, and tumor necrosis factor-α (TNF-α) were tested in different groups.

Results

Both ETR and PPR groups showed increased average blood perfusion and facial inflammation intensity by gray values compared to controls, with statistically significant differences. Average blood perfusion of ETR and PPR groups showed increased values in the forehead, cheeks, and nose, compared to controls, and the values in the cheeks were statistically different between ETR and PPR. The facial inflammation intensity of the ETR group showed increased values in the forehead and cheeks, and the PPR group showed increased gray values in the forehead, cheeks, nose, and chin compared to controls, and the values for the cheeks, nose, and chin were statistically significantly different between ETR and PPR. Plasma biomarkers IL-6, IL-1β, and TNF-α were significantly elevated in both ETR and PPR groups compared to controls.

Conclusion

LSCI is a valuable, non-invasive tool for assessing blood flow dynamics in rosacea, providing a data foundation for clinical research. Different rosacea subtypes exhibit distinct lesion distribution and blood flow patterns, and both ETR and PPR could affect all facial areas, particularly the cheeks in ETR and the forehead, nose, and chin in PPR.
Design of a Helicobacter pylori multi-epitope vaccine based on immunoinformatics
Authors: Cui Man , Ji Xiaohui , Guan Fengtao , Su Guimin , Du Lin
Published: August 2024

Helicobacter pylori (H. pylori) is an infectious bacterium that colonizes the stomach of approximately half of the global population. It has been classified as a Group I carcinogen by the World Health Organization due to its strong association with an increased incidence of gastric cancer and exacerbation of stomach diseases. The primary treatment for H. pylori infection currently involves triple or quadruple therapy, primarily consisting of antibiotics and proton pump inhibitors. However, the increasing prevalence of antibiotic resistance poses significant challenges to this approach, underscoring the urgent need for an effective vaccine. In this study, a novel multi-epitope H. pylori vaccine was designed using immunoinformatics. The vaccine contains epitopes derived from nine essential proteins. Software tools and online servers were utilized to predict, evaluate, and analyze the physiochemical properties, secondary and tertiary structures, and immunogenicity of the candidate vaccine. These comprehensive assessments ultimately led to the formulation of an optimal design scheme for the vaccine. Through constructing a novel multi-epitope vaccine based on immunoinformatics, this study offers promising prospects and great potential for the prevention of H. pylori infection. This study also provides a reference strategy to develop multi-epitope vaccines for other pathogens.