bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case Study on Online Design Workshop Experience: Gamification and Space
Authors:   Department of Interior Architecture, Faculty of Arts, Design and Architecture, FMV Isik University, Istanbul, Turkey, Karadag Derya , Gulbahar Simge ,   Department of Interior Architecture, Faculty of Arts, Design and Architecture, FMV Isik University, Istanbul, Turkey, Ozar Betul ,   Department of Interior Architecture, Faculty of Arts, Design and Architecture, FMV Isik University, Istanbul, Turkey
Published: September 2022

Design schools consist of three main axes; courses that provide knowledge in various fields of design, studio courses and internships. Besides, the indisputable fact is the importance of design competitions and informal workshops that feed the designer candidate to gain experience in different fields of the discipline. In addition, another importance of informal workshops is the contribution of researchers in this field to the development of design education. The effects and potentials of Information and Communication Technologies (ICTs) are also another area of research on design education, in particular design studio courses. The use of ICTs in the field of design education has led gamification to come to the fore as an ascending concept. A series of methodologies and tools have been developed, such as gamification, as well as the different kinds of Virtual Learning Environments to ensure the motivation of students and avoid the lack of attention in online courses. In this study, an online workshop, "Gamification and Space", is investigated as a case study. The contribution of the concept of gamification to design education has been evaluated in line with the observations and experiences gained. The data was gathered from the workshop presentations held on the last day and the final manuscripts of the workshops. The collected data was analyzed by the workshop coordination team, and classifications were made regarding the aspects of the gamification used during the workshop. In addition, it is aimed to discuss the potentials of ICTs in design courses. The observations show that the use of gamified elements has the potential to enrich instructional methods, especially when we consider online education, virtual learning environments and visual collaboration tools.
The Effect of Three-Dimensional Drawing on Learning Construction Detail Design in Interior Architecture Education
Authors:   Department of Interior Architecture and Environmental Design, Faculty of Fine Arts, Design and Architecture,  Başkent University, Ankara, Turkey, Moazemi Goudarzi Soufi , Seles Emre ,   Department of Interior Architecture and Environmental Design, Faculty of Fine Arts, Design and Architecture,  Başkent University, Ankara, Turkey
Published: September 2022

In the construction of the built environment, detailing is an important and inseparable part of the whole construction information. Giving practical construction information to interior architecture students is undoubtedly an important part of interior architecture education. Along with general building information, materials and detailing are included in the curricula of many interior architecture departments to strengthen students’ understanding of interior architecture practice. On the other hand, the detailing solution should be considered as a design-decision model to create design alternatives according to the building elements and material properties. The aim of this study is to show that structural and detailing problems should be considered in a holistic framework with the design in interior architecture education. The sub-purpose of this study is to show that the use of three-dimensional drawing techniques in interior architecture construction-detail education is effective in increasing a student’s ability to notice and learn building details. This study focuses on the use of three-dimensional drawing techniques in interior architecture education and the application-oriented solution of structural and detail problems. As a result, the method of the study suggests some design-decision modeling guidelines that will lead to better detail design-decision solutions for interior architecture students.
Ticari Bankalarda Likidite ve Kârlılık İlişkisi: Türk Bankacılık Sektörü Üzerine Bir Uygulama
Authors: KARAKAŞ Ahmet , ACAR Melek
Published: September 2022

Bankaların özellikle vade uyumsuzluğundan kaynaklanan likidite riskine karşı optimal düzeyde
likit varlık tutmaları, piyasa ve müşterilerin güvenini muhafaza edebilmeleri için oldukça önemlidir.
Ancak, likit varlık tutmanın kârlılığı da etkileyen fırsat maliyeti söz konusudur. Bu araştırmanın
amacı, ticari bankalarda likiditenin kârlılık ile ilişkisini araştırmaktır. Araştırmaya 2002-2020
döneminde Türkiye’de faaliyet gösteren 20 ticari banka dâhil edilmiş, bankalara ilişkin finansal
verilerde 2002 yılsonundan 2020 yılsonuna kadar çeyrek dönemler dikkate alınmıştır. Panel veri
analiz yöntemi ile yapılan araştırmada dirençli standart hatalar üretebilen tahmincilerden Driscoll-
Kraay, Parks-Kmenta ve Beck-Katz metotlarıyla tahminler yapılmıştır. Araştırma sonucunda; likit
varlık oranı ve cari oranın aktif kârlılığı oranını pozitif, özkaynak kârlılığı oranı ve net faiz marjını
negatif, asit-test oranının aktif kârlılığı oranını negatif, özkaynak kârlılığı oranı ve net faiz marjını
pozitif, kredi/mevduat oranının her üç kârlılık rasyosunu da negatif yönde etkilediği, bulguların
genel olarak likidite ile kârlılık arasında negatif yönlü bir ilişkiye işaret ettiği anlaşılmıştır.
Rebound Effect of Residential Space Heating: The Case of Ankara
Authors: Yilmaz Zehra Ilknur , SARI Ramazan , Sivrikaya Aysen , Fathurrahman Fahman
Published: September 2022

The direct rebound effect for space heating targeting households in Ankara, Turkey, is calculated by using primary and socio-economic indicators related data for energy efficiency applications in buildings. The demographic, dwelling characteristics, and behavioral factors that affect gas consumption are included in the analyses and are found to be crucial to assuring the successful implementation of energy efficiency technology in space heating.
Асимптотическое поведение решения дважды вырождающихся параболических уравнений с неоднородной плотностью
Authors: Dzagoeva L.F. , Tedeev A.F.
Published: September 2022

In this paper we study the large time behaviour for solutions to the Cauchyproblem for degenerate parabolic equations with inhomogeneous density.Under the suitable assumptions on the data of the problem and on the behaviour of the densityat infinity we establish new sharp bound of solutions for a large time.One of the main tool of the proof is new weighted embedding result whichis of independent interest. In addition, the proof of uniform estimatesof the solution is carried out by modified version of the classical methodof De-Giorgi--Ladyzhenskaya--Uraltseva--DiBenedetto. Similar resultsin the case of power-like density was obtained by one of the author~[10].The approach of this work can be applied for example when studying the qualitativeproperties of solutions to the Neumann problem for a doubly nonlinear parabolic equationwith inhomogeneous density in domains with non-compact boundaries.
Employability skills for civil engineers in Peru. Case study: San Antonio Abad del Cusco National University
Authors: Palomino Luz Marlene Nieto , Tello Jorge Iván Cruz , Huerta José Ronald Aguilar , Rivera Urpi Barreto
Published: September 2022

Recent modifications to the higher education system aim to ensure an education with high levels of employability; nevertheless, given the current economic climate, it is difficult for young professionals to launch their careers. In light of this circumstance, the authors of this research intend to identify and compare the talents that senior students, graduates, and professionals in civil engineering consider essential for entering the workforce. This study's data were gathered using a questionnaire survey completed by 243 individuals, and descriptive statistics were employed to characterize their perceptions. The results indicate that there are clear disparities in perception; also, it was shown that graduates have negative perceptions of their skills, which generates doubts about their ability to integrate into the market. This research is intriguing since it serves as a decision-making tool for the skills taught at the Professional School of Civil Engineering.
Rheological Study on Strength Characteristics of Sandcrete Hollow Block Admixed with Oil Palm Stem Ash
Authors:   Department of Civil Engineering, Ajayi Crowther University, Oyo, Oyo State, Nigeria, A. T. Adeyokunnu,
Published: September 2022

The study investigated the use of oil palm stem ash as partial replacement of OPC for sandcrete hollow block production which ranges from 0 to 25% (at 5% interval). Ninety six (96) sandcrete blocks were cast using 1:6 as mix ratio of cement: sand with 0.45 water cement ratio. The compressive strength, density, porosity and abrasion test were carried-out on sandcrete block were tested at curing age 7, 14, 21 and 28 days. The oil palm stem ash was analysed for chemical composition of (SiO2, Al2O3 and Fe2O3) in which the summation is 75.3%. it was observed that compressive strength and bulk density decreases as the content of OPSA increases but 5% of OPSA has value of 4.66N/mm2 and 2111.20Kg/m3 as against the control 5.12N/mm2 and 2162.01Kg/m3 respectively. The porosity and abrasion test revealed the increase in value as the percentage content of OPSA increased. It was concluded that OPSA is a good pozzolan having satisfied the required standard. which can be used as 10% of OPSA content insandcrete hollow block production having attained a 28 day compressive strength of more than 3.5N/mm2 as required by the Nigeria National Building Code (2007) for non load bearing wall.
The Effects of Corporate Governance, Intellectual Capital and Company Size on Financial Performance in Manufacturing Companies Lister on the Indonesia Stock Exchange for the Period of 2017-2021 in the Consumer Goods Industry Sector
Authors:   Economics and Business Faculty, Universitas Syiah Kuala, Banda Aceh, Nurhaliza Siti
Published: September 2022

This study aims to determine the relationship between corporate governance, intellectual capital, and company size with the financial performance of manufacturing companies in the consumer goods industry sector listed on the Indonesia Stock Exchange (IDX) in 2017–2021. The objective of this study, which falls under the genre of causal investigation, is to undertake research to identify the cause of one or more issues. This research sample approach employed purposeful sampling, which led to the collection of 70 firms. The analysis method used in this study is panel data regression with the E views program. The study’s findings suggest that the board of commissioners has a mixed impact on financial success. Financial performance is partially unaffected by the audit committee. Financial performance is partially influenced favorably by intellectual capital and firm size.
Research of Factors Affecting the Intention of Life Insurance Agents in Vietnam
Authors:   University of Labour and Social Affairs
Published: September 2022

The article presented the intention to leave the organization and related concepts. Through qualitative and quantitative research methods, the authors have built models and hypotheses to study the factors affecting the intention to leave the organization of life insurance agents in Vietnam. The research results confirm the impact of 6 factors on the intention to leave the organization of Vietnamese life insurance agents, including commitment to the business, job satisfaction, fairness in the business, ethical values, etc. Corporate ethics, career orientation, training. Combining the results of the analysis of the agent's assessment of the variables, the results of the analysis of the real situation of agent development and the current situation of the life insurance market in Vietnam, can serve as a basis for identifying limitations, proposed recommendations for life insurance businesses, the Vietnam Insurance Association and the State Administration to increase the proportion of full-time agents, thereby lowering the rate of leaving the organization Vietnam life insurance agent.
A linguistic analysis of representation of corruption and corruption-related clauses in Kenyan print media
Authors:   Department of Languages and Humanities School of Social Sciences Mount Kenya University
Published: September 2022

The purpose of this paper is to examine how language is used to represent the menace of corruption in Kenyan Print Media. Corruption has become a burning issue in Kenya as a country and in organizational research. It has been a long-standing debate in the Kenyan political and economic sphere, relevant not only at the national level but also having impact in rural areas where county governments were introduced through the 2010 constitution. However, few studies examine how corruption issue is socially constructed linguistically in print media. The study examines all reportage on corruption as a social issue in the Daily newspaper and the Standard Newspaper from February 2020 to February 2021. The study applied Fairclough’s (1989, 1990, 2001) Critical Discourse Analysis theoretical framework. The study employed analytical research design. The findings of the study revealed the use of linguistic elements that advance and amplify the reporting on corruption related issues. Such elements include the use of lexical items such as nouns and verbs, voice, epithets and indigenization. The results show that messages on corruption are framed in a persuasive manner to influence the readers and to evoke thoughts on this menace that has hardly affected the taxpayers. The study concludes that language is a powerful tool that newspaper writers use to influence the readers and to evoke thoughts on corruption that has hardly affected the taxpayers.
Infant Death due to Smothering
Authors:   Department of Forensics and Medicolegal, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia, Petrus Asan
Published: September 2022

Background: Infanticide has varying terminology and definitions in different jurisdictions. It is usually defined as the murder of a child in the first 24 hours of life, whereas in the US it is defined as the murder of a person one week or less. In the UK, the adultery of a baby, who is not yet one year old by his own mother is referred to as infanticide and is given a lighter sentence due to considerations of mental status. Meanwhile, in Indonesia, the basis for consideration used is the motive for fear of being caught giving birth to a child and the murder is carried out immediately during childbirth. As for determining that murder is the murder of one’s own child or ordinary murder, a forensic examination is required. Case: A case was reported with the victim of a baby boy in a cardboard box on the road around the housing complex and an examination of the body was carried out in the autopsy room of the Forensic Medicine and Medicolegal Medical Installation of Bhayangkara General Hospital, TK II Medan City according to the Visum Request Letter. Results: it was found that the baby was born alive, viabel, did not get treatment with the estimated age of the baby in the womb was 9-10 months (mature). The cause of death is due to exposure that causes suffocation due to the obstruction of air entering the respiratory tract. Discussion: On examination, the baby was estimated to be aged 9-10 months in the womb (viable). There is no sign of treatment. Bruises were found on the upper and lower lips of the outer and inner parts which indicated the presence of closure of the baby’s mouth by the perpetrator. There are also signs of asphyxia. On internal examination, a positive pulmonary buoyancy test was found and the results of pulmonary histopathology showed that the baby was viable and quite a month. Conclusion: The baby is a victim of murder, so the perpetrator must be held accountable for his actions and can be prosecuted under articles 341, 342 of the Criminal Code if the perpetrator is a biological mother and article 343 of the Criminal Code if there are people who help / do.
Kontribusi PT Berkah Rosul Bersaudara sebagai Mitra terhadap Pendapatan Petani Cabai Rawit Merah (Caplak) Bekancan di Desa Telagah Kecamatan Sei Bingai Kabupaten Langkat Sumatera Utara
Authors: Akbar Sitompul Febriandi , M. Nawawi Zuhrinal
Published: September 2022

In this case, the main problem is to know the contribution of PT. The Berkah Rosul Bersaudara  on the income of the red chili farming business. And there is also a request for the red chili farming business. The purpose of this research is to find out the various contributions made by PT Berkah Rosul Bersaudara  who are collaborating with bekancan red chili farmers in Telagah Village, Kec. Sei Bingai, Kab. Langkat, North Sumatra. The primary method and the secondary method are a form of method used in this study. By conducting research on groups of red chili farmers in the village. Interview activities that have been carried out to the leadership of the company PT Berkah Rosul Bersaudara and the farmers is an effort to obtain primary data. While secondary data is data that is indirectly obtained from literature books relevant to this research as well as several journals that also discuss the same topic. This research resulted in various forms of contributions that have been sought by the company as a partner to the income of red bekancan chili farmers in Telagah Village, Kec. Sei Bingai, Kab. Langkat, North Sumatra which is in accordance with the data that has been produced in the study that the red chili harvest of 5 hectares was declared successful with quite a lot of quantity, thus affecting the income of farmers which experienced a significant increase of 50%.

Keywords: Corporate Social Responsibility (CSR), Contribution, Income, Red Chilli Farmers, Private Companies
ZnO Multilayer Thin Films as The Seed Layer for ZnO Nanorods: Morphology, Structural and Optical properties
Authors: Abdul Rahman Rohanieza , Zulkefle Muhammad AlHadi , Herman Sukreen Hana , Alip Rosalena Irma
Published: September 2022

The effect of zinc oxide (ZnO) multilayer thin film thicknesses, deposited via the sol-gel spin coating technique, on the morphology, structural and optical properties of ZnO nanorods (ZNR) grown on the ZnO thin films were explored in this investigation. The ZNR was grown using the chemical bath deposition method on the ZnO thin film seed layer (SL). We found that ZnO thin film SL morphology changes according to the number of layers based on the results. Eventually, these changes also influence the structures of ZNR. ZNR structures improved when the thickness of the seed layer increased. Besides the surface roughness, better crystalline quality films were obtained when more layers were deposited. This crystalline quality then influenced the optical characteristics of both ZnO and ZNR thin films. The optical properties from UV-Vis showed transmittance in the visible region, showing that the ZnO films produced were suitable to be applied to solar cells. ZNR-based solar cells have become one of the promising materials to be studied further due to the environment-friendly, low-cost, and well-abundant material for solar cell applications.
DESIGN STRUGGLES: Intersecting Histories, Pedagogies, and Perspectives
Authors:   Humboldt University of Berlin
Published: September 2022

Design Struggles critically assesses the complicity of design in creating, perpetuating, and reinforcing social, political, and environmental problems — both today and in the past. The book proposes to brush the discipline against the grain, by problematizing Western notions of design, fostering situated, decolonial, and queer-feminist modes of disciplinary self-critique. In order to reimagine design as an unbound, ambiguous, and unfinished practice, this publication gathers a diverse array of perspectives, ranging from social and cultural theory, design history, design activism, sociology, and anthropology, to critical and political studies, with a focus on looking at design through the intersections of gender, race, ethnicity, culture, class, and beyond. It combines robust scholarly insights with engaging and accessible modes of conveyance and storytelling by bringing together an urgent and expansive array of voices and views from those engaged in struggles with, against, or around the design field.
Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study
Authors: Al Awaidy Salah T. , Khamis Faryal , Al-Zakwani Ibrahim , Al Kindi Shadha , Al Busafi Suad , Al Sulaimi Khalsa , Al Sidiari Hilal
Published: September 2022

Objectives: Dengue fever (DF) is the most common arthropod-borne viral illness with significant public health implications that can cause severe clinical symptoms and possibly death. We sought to determine the epidemiological and clinical characteristics of patients presented with DF to the Royal Hospital in a recent outbreak in Oman. Methods: We conducted a retrospective cohort study between 1 January and 18 April 2022, at the Royal Hospital, Oman, including all patients who presented with febrile illness and laboratory-confirmed DF. Descriptive statistics were used to summarize the results. Results: The cohort included 58 patients with laboratory-confirmed DF, of whom 39 (67.2%) required admission. The overall mean age was 41.0±20.0 years. Over half (55.2%) were females and the majority (86.2%) were Omani citizens. Eighty-one percent of the patients were residents of Bawshar in Muscat governorate. Dengue virus 2 was the isolated serotype. Fever (98.3%), muscular aches and pains (55.2%), and headache (53.4%) were the most common symptoms on presentation. All patients except two had no travel history. The most common comorbidities were hypertension (29.3%) and diabetes mellitus (17.2%). Upon admission, the most prominent hematological and biochemical abnormalities were severe thrombocytopenia (31.0%) with platelet counts of < 50 000/mm3 and hepatic impairment (15.5%). Antibiotics were prescribed to 27.6% of the patients. All patients improved clinically, and no deaths were reported during the study period. Conclusions: Fever and thrombocytopenia were the commonest presentations of DF. Identification of factors linked to increased risk of hospitalization in patients with DF can assist in recognizing individuals who need close monitoring and intensive support.
geoeconomia da transpetro nos territórios paranaense e catarinense
Authors: Alves Costa Pierre
Published: September 2022

O objetivo principal desta pesquisa é refletir sobre as espacialidades geoeconômicas da Transpetro nos territórios paranaense e catarinense. Para a sua confecção, realizamos a leitura e reflexão da bibliografia levantada. Como forma de apoio ao entendimento da questão petrolífera, também utilizamos uma gama variada de fontes, como: jornais, anuários e documentos; informações coletadas em visitas técnicas à Refinaria Presidente Getúlio Vargas (REPAR), PR; e aos Terminais Aquaviários de Paranaguá (TEPAR), PR, e São Francisco do Sul (TEFRAN), SC. Como resultado, verificamos que o esforço nacional para construir a infraestrutura da indústria petrolífera brasileira, a partir dos anos 1940, começa a ser destituído a partir de 2016 com governos neoliberais; principalmente com o processo de privatizações.
Effectiveness of upper limb endurance and resistance exercises on reducing dyspnoea and improving activities of daily living (ADL) in patients with COPD
Authors: Devadarshini  , N. Shazia Neelam , P. Senthil , S. Subramanian
Published: September 2022

Introduction and Aim: Chronic Obstructive Pulmonary Disease (COPD) is preventable and treatable disease, presenting permanent airflow limitation accompanying an augmented chronic inflammatory response in the airway and the lungs to harmful elements or gases. Chronic bronchitis and emphysema are the two most common conditions that contribute to COPD, individuals with COPD often experience difficulty with performing upper limb exercise due to dyspnoea and arm fatigue. Consequently, upper limb exercise training is habitually included in lung rehabilitation programmes to advance upper limb exercise tolerance; yet the effects of this exercise on dyspnoea and activities of daily living remain unclear. The aim of this analysis is to determine the effects of upper limb endurance and resistance exercises on reducing dyspnoea and improving activities of daily living (ADL) in patients with COPD.
Methodology: This is an experimental study design and was conducted in a clinical set-up of Physiotherapy Department with a total number of 10 samples selected based on the Inclusion and Exclusion criteria. All the participants underwent endurance and resistance exercises to the upper limb for 20 Minutes session for 3 days per week for 4weeks. Pre- and post-treatment assessments were done using the outcome measures Modified Borg Scale and London Chest Activity of Daily Living Scale. 
Results: The findings of the study revealed improved clinical outcomes in the study group. Calculation of mean and median values and then performing a paired t test of within group between pre-test and post-test values, it shows highly significant difference with a p value of p < 0.001. 
Conclusion: This study shows that there is a significant improvement in the COPD patients after the treatment implying that Upper Limb Endurance and Resistance Exercises were beneficial in improving ADL and reducing dyspnoea in COPD patients. Future research suggests recommendation of early COPD treatment in both genders.
The study of urban form in the Netherlands
Authors: Marzot Nicola , Cavallo Roberto , Komossa Susanne
Published: September 2022

The study of urban form in the Netherlands has been heavily influenced by the Modern Movement and characterized by strong disciplinary specialization. On the one hand there is the distinction between art and engineering and on the other the search for instrumental universal rationality. This helps to explain the increasing interest, initially within academe, in the first English and German translations of some outstanding works of Italian researchers, who were at the time already acting as leaders in new perspectives in the fields of urban form and architecture. In keeping with the Dutch practical attitude, these investigations contributed to urban developments of the post-industrial era, beginning at the end of the 1970s. Today much of the study of urban form entails investigation of how global trends affect local systems and how local systems can be improved by analysing best practices. In that respect the Netherlands has been able to establish a leading role in contemporary architecture that is widely recognized within Europe.
Caracterización y manejo clínico de pacientes con trombastenia de Glanzmann en un hospital universitario de referencia en hemostasia en Bogotá, Colombia
Authors: Chávez Karena , Solano María Helena , Casas Claudia Patricia
Published: September 2022

Introducción: la trombastenia de Glanzmann es un trastorno hereditario de las plaquetas, con herencia autosómica recesiva, el cual presenta una baja prevalencia en la población mundial. Se manifiesta usualmente desde la infancia con sangrado en piel y mucosas, petequias y equimosis; en mujeres el sangrado ginecológico es una de las principales manifestaciones, pueden existir casos de sangrado mayor, ante eventos quirúrgicos o trauma. El tratamiento está basado en transfusión de plaquetas, uso de agentes antifibrinolíticos como ácido tranexámico y factor VIIa recombinante.
Objetivo: describir las características demográficas, clínicas, así como las principales estrategias de tratamiento en los pacientes con diagnóstico de trombastenia de Glanzmann en un centro hospitalario. Materiales y métodos: cohorte descriptiva en un periodo de 10 años, tipo serie de casos de pacientes mayores de 18 años, con diagnóstico de trombastenia de Glanzmann. Las variables cualitativas se describieron mediante frecuencias absolutas y relativas, y las variables cuantitativas con medidas de tendencia central y de dispersión, según su distribución. Análisis de datos realizado en STATA 13®.
Resultados: se reportan 9 pacientes, con un total de 34 ingresos hospitalarios, 23 ingresos debidos a sangrado y 11 por eventos quirúrgicos; la mayoría de pacientes fueron mujeres en un 77 % y la mediana de edad es de 37 años. En total se realizaron 16 procedimientos quirúrgicos, cinco de ellos, procedimiento mayor. El tratamiento más frecuente fue el uso de antifibrinolíticos en 28 casos, seguido por uso de plaquetas en 19 casos y factor VIIa en 17 de ellos. Uso conjunto de antifibrinolíticos, plaquetas y factor VIIa en 7 casos. La media de días de estancia hospitalaria fue de 8 días. Durante el seguimiento no hubo mortalidad reportada.
Conclusiones: la trombastenia es una enfermedad con una incidencia baja, con manifestaciones importantes de sangrado, afectando a hombres y mujeres, aunque las mujeres tienen manifestaciones clínicas más frecuentes y mayor compromiso. El manejo del sangrado es un reto, ya sea en el escenario del evento de sangrado o en el manejo quirúrgico para garantizar la hemostasia.
Aplicación clínica del perfil genómico integral para la toma de decisiones terapéuticas en pacientes colombianos con tumores sólidos avanzados
Authors: Carranza Isaza Hernán , Otero Bernal Jorge Miguel , Vargas Baéz Carlos Alberto , Ruiz Patiño Alejandro , Sotelo Rodríguez Diana Carolina , Rodríguez Ariza July Katherine , Rojas Puentes Luis Leonardo , Cardona Zorrilla Andrés Felipe , Archila Gómez María del Pilar
Published: September 2022

Introducción: el desarrollo de nuevas tecnologías de diagnóstico molecular ha permitido la detección de numerosas alteraciones del genoma involucradas en el inicio y progresión del cáncer. Desempeña un rol importante la identificación de variantes de utilidad clínica o mutaciones accionables, entendidas como aquellas alteraciones puntuales que permiten guiar las decisiones terapéuticas con inhibidores dirigidos a estos blancos moleculares. El éxito de estos agentes ha llevado a un cambio de paradigma, a tal punto de reemplazar la quimioterapia convencional en un grupo selecto de pacientes que se benefician de terapia dirigida. La secuenciación de nueva generación (NGS, por sus siglas en inglés) es la base de las plataformas genómicas con las que se puede realizar un perfil genómico completo (CGP, por sus siglas en inglés), con el objetivo de identificar las mutaciones accionables sobre las cuales ejercerán su efecto los fármacos dirigidos, permitiendo así la medicina personalizada y oncología de precisión, sin embargo, la utilidad clínica de CGP en pacientes colombianos es desconocida. Objetivos: el objetivo principal de este estudio fue evaluar la utilidad clínica del perfil genómico integral en tumores sólidos durante la práctica clínica habitual en Colombia como recomendación de tratamiento.
Gençlerin Somut Kültürel Miras Farkındalığı: Erasmus+ Projesi Deneyiminden Perspektifler
Authors: HARMAN ASLAN Ebru , DİKER Melisa
Published: September 2022

Kültürel miras, ait olduğu toplumdaki somut ve soyut değerli varlıkları, olayları, bilgileri yansıtan kaynaklardır. Bu mirasın çağdaş, bilimsel, yenilikçi ve sürdürülebilir yöntemlerle korunması için toplumsal farkındalık düzeyinin artması gerekmektedir. Özellikle de gençlerin kültürel miras farkındalığını ve koruma süreçlerine katılımlarını artırmayı amaçlayan faaliyetler geliştirilmelidir. Bu çalışmada, gençler arasındaki somut kültürel miras ve korunmasına ilişkin farkındalık düzeyini arttırmaya yönelik “Geçmişten Geleceğe” isimli Erasmus+ Gençlik Değişimi projesi deneyimlerini paylaşmak ve projenin amacına ulaşma/başarılı olma düzeyini değerlendirmek amaçlanmıştır. Sekiz aylık bir takvime yayılan “Geçmişten Geleceğe” Erasmus+ Gençlik Değişimi projesine, üç farklı ülkeden 43 genç katılmıştır. Projede somut kültürel miras varlıkları hakkında “neyi, neden, nasıl koruyoruz?” temalarıyla hazırlanan 14 aktivite gerçekleştirilmiş ve aktivitelere ek olarak katılımcılara anket uygulanmıştır. Projede yapılan aktivitelerin çıktıları uzmanlar tarafından yorumlanarak; elde edilen anket bulguları ise betimleyici analiz kullanılarak değerlendirilmiştir. Sonuç olarak, proje sonunda gençlerin çoğunlukla somut kültürel mirasın tanımı, kapsamı ve sınıflandırmaları hakkında bilgi sahibi oldukları, miras varlığının korunmasının altında yatan sebep olan kültürel miras değerlerini kavradıkları, bu değerlerin en çok toplumsal farkındalık düzeyini arttırarak korunabilineceğinin bilincinde oldukları ve benzer projelere katılma eğiliminde oldukları söylenebilir. Bu sonuçlar, “Geçmişten Geleceğe” Erasmus+ Gençlik Değişimi projesinin gençlerin kültürel mirasa yönelik bilgi, deneyim, duyarlılık ve farkındalık düzeylerini arttırıcı ve koruma süreçlerine katılımlarını teşvik edici bir rol oynadığına işaret etmektedir.
Optimising the Depolymerisation of PET Fleece Microplastics Through Microwave Irradiation
Authors:   Westdale Secondary School, Hamilton, ON, Canada, Adronov Rya
Published: September 2022

Polyethylene terephthalate (PET) is one of the world’s most used plastics. Amenable to both mechanical and chemical recycling processes, PET is also commonly recycled. Chemical recycling processes of PET include glycolysis, which produces bis(2-hydroxyethyl) terephthalate (BHET); this is then re-polymerised to form new PET. One novel method for PET glycolysis involves microwave irradiation of PET water bottles in the presence of a catalyst and, notably, a microwave absorber. The research presented here investigates the optimisation of this novel method for PET fleeces. Samples were prepared using constant amounts of solvent, fleece, and microwave absorber. The conditions chosen to be varied and optimised were catalyst loading, irradiation time, and reaction temperature. Multiple variations of these conditions underwent the course of experimentation and were analysed through high performance liquid chromatography (HPLC) to determine their composition. The conditions used in samples that produced the highest yield of BHET were determined to be optimal. These conditions were found to be a catalyst loading of 2 mg, an irradiation time of 3 minutes, and a reaction temperature of 250°C. It has recently been observed that a substantial portion of microplastic pollution in bodies of water (which greatly impacts the environment) can be attributed to fleece microfibres, which are composed of PET. Through the capture and depolymerisation of fleece microfibres before release, this research could play an important role in the reduction of the amount of PET microfibre polluting the world’s oceans in the future.
Latitudinal Dependence of the Geomagnetic and Solar Activity Effect on Sporadic-E layer
Authors: Tang Qiong , Zhou Chen , Liu Huixin , Liu Yi , Zhao Jiaqi , Yu Zhibin , Zhao Zhengyu , Feng Xueshang
Published: September 2022

Abstract. Based on the global COSMIC occultation data, the latitudinal dependence of the geomagnetic and solar activity effect on the sporadic-E (Es) layer is investigated. Statistical results demonstrate that the relationship between Es layer occurrence rate and geomagnetic activity shows no correlation in low geomagnetic latitudes, a negative correlation in middle geomagnetic latitudes, and a positive correlation in high geomagnetic latitudes. The decrease in Es layer occurrence rate during geomagnetic activity in middle geomagnetic latitudes may be due to the descending meteor rate caused by the atmospheric density change during the geomagnetic storm. While the increase in Es layer occurrence rate in high geomagnetic latitudes is mostly related to the ionospheric electric field change driven by the international magnetic field (IMF) embedded within the solar wind. Solar activity effect on the Es layer also presents latitudinal dependence, with negative correlation in low and middle geomagnetic latitudes and positive correlation in high geomagnetic latitudes. The negative correlation may be owing to the negative correlation between meteor rate and solar activity revealed by many previous studies. The positive correlation in high geomagnetic latitudes is mostly related to the enhanced IMF during solar maximum.
High-resolution vertical biogeochemical profiles in the hyporheic zone reveal insights into microbial methane cycling
Authors: Michaelis Tamara , Wunderlich Anja , Coskun Ömer K. , Orsi William , Baumann Thomas , Einsiedl Florian
Published: September 2022

Abstract. Facing the challenges of climate change, policy making
relies on sound greenhouse gas (GHG) budgets. Rivers and streams emit large
quantities of the potent GHG methane (CH4), but their global impact on
atmospheric CH4 concentrations is highly uncertain. In situ data from
the hyporheic zone (HZ), where most CH4 is produced and some of it can
be oxidized to CO2, are lacking for an accurate description of CH4
production and consumption in streams. To address this, we recorded
high-resolution depth-resolved geochemical profiles at five different
locations in the stream bed of the river Moosach, southern Germany.
Specifically, we measured pore-water concentrations and stable carbon
isotopes (δ13C) of dissolved CH4 as well as relevant
electron acceptors for oxidation with a 1 cm vertical depth resolution.
Findings were interpreted with the help of a numerical model, and 16S rRNA
gene analyses added information on the microbial community at one of the
locations. Our data confirm with pore-water CH4 concentrations of up
to 1000 µmol L−1 that large quantities of CH4 are produced in
the HZ. Stable isotope measurements of CH4 suggest that
hydrogenotrophic methanogenesis represents a dominant pathway for CH4
production in the HZ of the river Moosach, while a relatively high abundance of
a novel group of methanogenic archaea, the Candidatus “Methanomethyliales” (phylum
Candidatus “Verstraetearchaeota”), indicate that CH4 production through H2-dependent methylotrophic methanogenesis might also be an important CH4
source. Combined isotopic and modeling results clearly implied CH4
oxidation processes at one of the sampled locations, but due to the steep
chemical gradients and the close proximity of the oxygen and nitrate
reduction zones, no single electron acceptor for this process could be
identified. Nevertheless, the numerical modeling results showed
potential not only for aerobic CH4 oxidation but also for anaerobic oxidation
of CH4 coupled to denitrification. In addition, the nitrate–methane
transition zone was characterized by an increased relative abundance of
microbial groups (Crenothrix, NC10) known to mediate nitrate and nitrite-dependent
methane oxidation in the hyporheic zone. This study demonstrates substantial CH4 production in hyporheic
sediments, a potential for aerobic and anaerobic CH4 oxidation, and
underlines the high spatiotemporal variability in this habitat.
Holocene history of 79° N ice shelf reconstructed from epishelf lake and uplifted glacimarine sediments
Authors: Smith James A. , Callard Lousie , Bentley Michael J. , Jamieson Stewart S. R. , Sánchez-Montes Maria Luisa , Lane Timothy P. , Lloyd Jeremy M. , McClymont Erin L. , Darvill Christopher M. , Rea Brice R. , O'Cofaigh Colm , Gulliver Pauline , Ehrmann Werner , Jones Richard S. , Roberts David H.
Published: September 2022

Abstract. Nioghalvfjerdsbrae, or 79° N Glacier, is the largest marine-terminating glacier draining Northeast Greenland Ice Stream (NEGIS). In recent years, it’s ~70 km-long fringing ice shelf (hereafter referred to as 79° N ice shelf) has thinned, and a number of small calving events highlight its sensitivity to climate warming. With the continued retreat of 79° N ice shelf and the potential for accelerated discharge from NEGIS, which drains 16 % of the Greenland Ice Sheet (GrIS), it has become increasingly important to understand the long-term history of the ice shelf in order to put the recent changes into perspective and to judge their long-term significance. Here we reconstruct the Holocene dynamics of 79° N ice shelf by combining radiocarbon dating of marine mollusc from isostatically uplifted glacimarine sediments with a multi-proxy investigation of two sediment cores recovered from Blåsø, a large epishelf lake 2–13 km from the current grounding line of 79° N Glacier. Our reconstructions suggest that the ice shelf retreated between 8.5 and 4.4 cal. ka. BP, which is consistent with previous work charting grounding line and ice shelf retreat to the coast, and open marine conditions in Nioghalvfjerdsbrae. Ice shelf retreat followed a period of enhanced atmospheric and ocean warming in the Early Holocene. Based on our detailed sedimentological, microfaunal and biomarker evidence the ice shelf reformed at Blåsø after 4.4 cal. ka BP, reaching a thickness similar to present by 4.0 cal. ka BP. Reformation of the ice shelf coincides with decreasing atmospheric temperatures, increased dominance of Polar Water, a reduction in Atlantic Water and (near) perennial sea-ice cover on the adjacent continental shelf. Together with available climate archives our data indicate that 79° N ice shelf is susceptible to collapse when mean atmospheric and ocean temperatures are ~2 °C warmer than present, which could be achieved by the middle of this century under some climate model scenarios. Finally, the presence of ‘marine’ markers in the uppermost part of the Blåsø sediment cores could record modern ice shelf thinning, although the significance and precise timing of these changes requires further work.
La Francia des tsiganes. El “proyecto civilizatorio” y la irrupción del movimiento romaní (1949-1969)
Authors: Barrera Begoña
Published: September 2022

Este artículo aborda el tratamiento que los poderes públicos, por un lado, y el movimiento romaní, por otro, dieron a la llamada “cuestión tsigane” (gitana o romaní) en la Francia posterior a la Segunda Guerra Mundial. Su objetivo es analizar las características y la evolución de ambas partes, atendiendo tanto al discurso civilizatorio que vertebró la primera de ellas (la de los autodenominados “amigos de los tsiganes”), como a la reacción que la segunda (la liderada por los propios romaníes) mostró frente al paternalismo de los no-tsiganes. Las conclusiones sostienen que, frente a la visión excesivamente dicotómica y simplista que la historiografía ha dado sobre los perfiles y a la relación entre poderes públicos y movimiento romaní, la vinculación entre ellos estuvo cargada de tensiones, conflictos y acercamientos que potenciaron la pluralidad de ambos.
قياس مدى تقبل معلمات قرى محافظة جدة نحو التعليم الإلكتروني وأبرز المعوقات التي تواجهن
Authors:   باحثة ماجستير في القيادة التربوية، كلية العلوم الصحية والسلوكية والتعليم، جامعة دار الحكمة، المملكة العربية السعودية, الحافظي أمل , العباسي دلال ,   مديرة قسم ماجستير القيادة التربوية، كلية العلوم الصحية والسلوكية والتعليم، جامعة دار الحكمة، المملكة العربية السعودية
Published: September 2022

هدفت الدراسة إلى التعرف على مدى تقبل معلمات قرى محافظة جدة للتعليم الإلكتروني، وتحديد أبرز المعوقات استخدام التعليم الإلكتروني من وجهة نظر معلمات قرى محافظة جدة. اعتمدت الباحثة في إعداد هذه الدراسة على المنهج الوصفي التحليلي، ويتكون مجتمع الدراسة من معلمات المدارس الحكومية في قرى محافظة جدة (رابغ-خليص) بالمملكة العربية السعودية، وتكونت عينة الدراسة من (252) معلمة، ولتحقيق أهداف الدراسة تم اعتماد الاستبانة كأداة لجمع البيانات من العينة. وتوصلت الدراسة إلى أهم المتغيرات المؤثرة في استخدام التعليم الإلكتروني هو مدى السهولة أن أصبح ماهرة في استخدام أنظمة التعليم الإلكتروني، وبالنسبة لمتغير الفوائد المتوقعة فقد أكدت عينة الدراسة على زيادة التفاعل الأكاديمي بين الطالبات بعضهم البعض وبينهم وبين معلماتهم تعد من أهم الفوائد المتوقعة من استخدام نظام التعليم الإلكتروني، من أبرز المعوقات التي تواجه التعليم الإلكتروني في قرى محافظة جدة ضعف الاتصال أحياناً بشبكة الإنترنت. كما خلصت الدراسة إلى مجموعة من التوصيات، منها أنه يجب على وزارة التعليم ممثلة في إدارة التعليم الإلكتروني مساعدة المعلمات في تأكيد أو زيادة تصوراتهم الإيجابية حول نظام التعليم الإلكتروني من خلال تطوير محتوى التعليم الإلكتروني ليكون أكثر سهولة وأكثر توجيها للمستخدم، وكذا تقديم دورات تدريبية أساسية ومستمرة لتمكينهن من استخدام هذه التقنية وفهمها.
السياسة الاقتصادية السعودية ودورها في جذب الاستثمار الأجنبي المباشر وآثاره على الاقتصاد السعودي
Authors:   دكتوراه في إدارة الأعمال، كلية إدارة الأعمال، جامعة لينكولن، ماليزيا, الأصلعي محمد , شمسي محمد ,   دكتوراه في إدارة الأعمال، جامعة بورغوني، ديجون، فرنسا
Published: September 2022

هدفت الدراسة الى الوقوف على ماهية السياسة الاقتصادية ومكوناتها والعوامل التي تؤدي إلى بناء سياسة اقتصادية ناجحة. وتناول أدوات السياسة المالية والنقدية والسياسة التجارية والتنسيق بينهما ودورها في تحقيق الاستقرار الاقتصادي. وأن اللجوء إلى الاستثمار الأجنبي المباشر كظاهرة لها الأثر على هيكل الاقتصاد في الدول المتقدمة والنامية على حد سواء. بالإضافة الى تقديم لمحة مختصرة عن هيكل الاقتصاد السعودي والمراحل التي مر بها الاقتصاد قبل اجراء هذا البحث. وابراز دور السياسة الاقتصادية وتأثيرها في جذب الاستثمار الأجنبي المباشر إلى المملكة العربية السعودية. وإبراز مقومات الاقتصاد السعودي وقدرته على المنافسة وما يميز المملكة العربية السعودية عن دول العالم الثالث. وإبراز أثر الاستثمار الأجنبي المباشر على نقل التكنولوجيا ورفع كفاءة اليد العاملة السعودية والنمو والتحفيز الاقتصادي. وبناءً على تحليل البيانات واختبار الفرضيات في الفصل الرابع، يمكن تلخيص نتائج البحث الناتجة عن هذا العمل على النحو التالي: تعتبر السياسة الاقتصادية السعودية الاستثمار الأجنبي المباشر من وجهة نظر الافراد التي شملتها أفراد العينة، في المستوى المتوسط مما يشير إلى مستوى متوسط من التنفيذ، يعتبر النمو، التحفيز الاقتصادي، تنمية رأس المال البشرى والتوظيف، اكتساب الخبرة ونقل المهارة والتكنولوجيا من وجهة نظر الافراد التي شملتها العينة، في المستوى المتوسط مما يشير إلى مستوى متوسط من التنفيذ، هناك أثر ذو دلالة إحصائية للسياسة الاقتصادية السعودية على جذب الاستثمار الأجنبي المباشر عند مستوى دلالة α ≤ 0.05، يوجد أثر ذو دلالة إحصائية للاستثمار الأجنبي المباشر على الاقتصاد السعودي من حيث (النمو والتحفيز الاقتصادي وتنمية رأس المال البشرى والتوظيف واكتساب الخبرة ونقل المهارة والتكنولوجيا) عند مستوى دلالة α ≤ 0.05، الحاجة إلى توفير مناخ استثماري جاذب لرؤوس الأموال الأجنبية، وهو ما يجب أن يقوم على سياسة ضريبية متوازنة وامتيازات في مختلف المجالات تدفع الشركات الأجنبية إلى إقامة استثمارات دون الخوف من عليها، الاستثمار الأجنبي المباشر من أهم أدوات نقل التكنولوجيا، بسبب نقل العملية الإنتاجية من البلدان المصنعة إلى البلدان النامية ما يرافقه نقل التكنولوجيا بشقيها الصلب (الجانب المادي من وسائل إنتاج) واللين (الجانب المعرفي كبرامج التشغيل وطرق الإدارة الحديثة).
مستوى المناعة النفسية لدى أخصائيات التوحد بمستشفى القوات المسلحة بمدينة الطائف
Authors:   ماجستير في الإرشاد النفسي، قسم علم النفس، كلية التربية بجامعة أم القرى، المملكة العربية السعودية, الريشي روان
Published: September 2022

هدف هذه الدراسة التعرف على مستوى المناعة النفسية لدى أخصائيات التوحد بمستشفى القوات المسلحة بمدينة الطائف والكشف عن الفروق في المناعة النفسية لديهم التي تعزى لاختلاف المؤهل العلمي وسنوات الخبرة، استخدمت الباحثة المنهج الوصفي وتكونت عينة الدراسة من (31) أخصائية توحد، تم العمل على أداة الاستبانة وكانت من إعداد الباحثة والتأكد من صدقها وثباتها كأداة، حيث تم استخدم الأساليب الإحصائية المناسبة لطبيعة الدراسة، وتوصلت إلى عدد من النتائج أهمها: توجد مناعة نفسية عالية لدى أخصائيات التوحد بمستشفى القوات المسلحة بمنطقة الطائف، حيث بلغ المتوسط الحسابي الوزني لمجموع استجابات أفراد العينة على استبانة المناعة النفسية ككل (4.177). وقد تراوحت المتوسطات الحسابية الموزونة لاستجابات عينة الدراسة في هذه الاستبانة بمختلف أبعاده بين (4.05 )، و(4.33). كما أنه لا توجد فروق ذات دلالة احصائية عند مستوى الدلالة (0.05) للمناعة النفسية تعزى لاختلاف المؤهل الدراسي بين متوسطات استجابات عينة الدراسة على أبعاد المناعة النفسية حيث بلغت قيم مستويات الدلالة للأبعاد ( 0.697- 0.904)، وهي قيم أكبر من مستوى الدلالة (0.05 )، مما يشير إلى عدم وجود فروق تعزى لمتغير المؤهل العلمي. ايضاً عدم وجود فروق ذات دلالة إحصائية عند مستوى الدلالة (0.05) بين متوسطات إجابات أفراد عينة البحث في أبعاد استبانة المناعة النفسية، وفي الاستبانة ككل تعزى لاختلاف سنوات الخبرة، حيث جاءت قيم الاحتمال المعنوية المصاحبة للقيمة (ت) أكبر من مستوى المعنوية (0.05)، مما يشير إلى تقارب استجابات الأخصائيات نحو مستوى المناعة النفسية، ولا أثر لاختلاف سنوات الخبرة على وجهات نظرهم.