bluuebunny/crossref_metadata_2025 huggingface dataset:
Causes and Nature of Educational Neglect in German Research
Authors: Pylypiuk Kateryna M.
Published: July 2022

The relevance of the study is conditioned by the need to find out the causes of pedagogical neglect of adolescents in the context of German experience and identify possible solutions to this problem. The purpose of the study is to highlight the main views of German researchers on the diagnosis of pedagogical neglect and its further correction. From a methodological standpoint, the study is based on the content analysis method, which is one of the tools for conducting desk research. The studies by K. Lissmann, W. Von Humboldt, R.D. Precht, P. Wisner, G. Kindler were considered. The main problems that ensure educational neglect in Germany have been identified: insufficient funding, lack of highly qualified staff, misdirection of skills and qualities of students, low level of social security, etc. An important factor is the quality of relationships between teenagers and other people (parents, teachers, friends), as well as their parents with them. Recommendations were outlined for solving the above-mentioned problematic issues, which is the practical significance of the study. In particular, it is necessary to: increase funding to ensure the organisation of the educational process, increase the number of quotas in teachers’ universities, develop a new educational programme that will meet European standards, but at the same time not harm the local education system, ensure social protection of all participants in the educational process
Caracterização da expressão de GLUT1 em linfomas de células B agressivos
Authors: Cury Neto Farid , Garcia Gabriel de Prince , Bonatelli Murilo , Otteiro José Augusto Santanna , Barbin Flávia Fazzo , Da Silva Eduardo Caetano Albino , Alves Wilson Eduardo Furlan Matos , Pinheiro Céline
Published: July 2022

Introdução: Os linfomas de células B agressivos (LCBA) representam um grupo de neoplasias de rápida evolução, originados da transformação maligna de linfócitos B no folículo linfoide. Estas células tumorais passam por uma reprogramação metabólica, com ênfase no aumento da atividade da via glicolítica e acúmulo de lactato, mesmo na presença de oxigênio (efeito Warburg). Estas alterações dependem do aumento da atividade/expressão de proteínas, como o transportador de glicose GLUT1. O radiotraçador e análogo de glicose 2-(flúor-18)flúor-2-desoxi-D-glicose ( 18F-FDG) também alcança o meio intracelular através dos GLUTs, sendo que a sua captação em linfomas, é utilizada para predição prognóstica e avaliada pela tomografia com emissão de pósitron fusionada à tomografia computadorizada (PET-CT). Apesar do 18F-FDG-PET- CT ter um papel estabelecido no estadiamento de linfomas, existem poucos estudos avaliando o papel prognóstico da expressão de GLUT1 nessa neoplasia. Objetivos: Avaliar a expressão imunohistoquímica de GLUT1 e associá-la a dados clinicopatológicos e de sobrevivência, e a parâmetros semi-quantitativos referentes à captação de 18F-FDG. Métodos: O atual estudo é baseado em um desenho longitudinal com coleta retrospectiva de dados clínico-laboratoriais, análise de amostras de biópsias de LCBA e de parâmetros semi-quantitativos referentes à captação de 18F-FDG pelo tecido neoplásico de 90 pacientes com LCBA. Foi realizada coleta de dados clinicopatológicos dos pacientes, será realizada imunohistoquímica em cortes parafinados de biópsias para a avaliação da expressão de GLUT1 e, por fim, análise estatística utilizando o SPSS. Resultados parciais: A maioria dos pacientes incluídos encontrava-se em estágio avançado da doença (58,9%), apresentava envolvimento de sítios extranodais (80,0%) e foi tratada com R-CHOP (81,1%). Além disso, 13,3% dos pacientes apresentaram progressão da doença e 17,8% vieram a óbito. Atualmente, está sendo realizado o processamento de imagens e coleta de dados de PET-CT, assim como foram iniciadas as reações de imunohistoquímica, porém, a avaliação pelos patologistas ainda não foi iniciada.
Expressão de transportadores de monocarboxilatos em câncer de pênis
Authors: Ynomoto Leandra Akemi Pistori , Araújo Hadson Silva , Bonatelli Murilo , Teixeira Gustavo Ramos , Cárcano Flávio Mavignier , Pinheiro Céline Marques
Published: July 2022

Introdução: O câncer de pênis é uma neoplasia rara, com maior prevalência em países subdesenvolvidos. É mais comum em homens a partir da sexta década de vida, com fatores de risco envolvendo má higiene e infecções sexualmente transmissíveis. No câncer, a reprogramação do metabolismo celular favorece a progressão da doença, sendo que nas neoplasias mais agressivas ocorre aumento da expressão de certas proteínas, como os transportadores de monocarboxilatos (MCTs). A expressão de MCT1 e MCT4 muda o microambiente tumoral, favorecendo a agressividade tumoral. Os MCTs ainda não foram descritos em carcinomas de pênis. Objetivos: Avaliar a expressão de transportadores de monocarboxilatos no câncer de pênis e associar a sua expressão com os dados clínicos e patológicos dos pacientes. Metodologia: Por imunohistoquímica, a expressão proteica de MCT1 e MCT4 será avaliada em cerca de 180 amostras de carcinoma peniano. A expressão imunohistoquímica será avaliada (em extensão e intensidade) por patologista e associada aos dados clínicos e patológicos dos pacientes utilizando o SPSS. Resultados preliminares: Os dados clínico-patológicos de 115 pacientes foram coletados, a coleta do restante ainda ocorre. Os dados preliminares sugerem uma amostra bem heterogênea. É maior a frequência de indefinição de cor de pele. A maioria dos pacientes procede da região Sudeste. Quanto a intervenções cirúrgicas prévias, 23,3% negou cirurgias penianas. Histologicamente, 92,6% da amostra são classificadas como carcinoma epidermoide (CEC). Cerca de 17% das neoplasias eram metastáticas ao diagnóstico. No pré e no pós-tratamento, a frequência maior de classificação clínica para carcinomas por grupos foi o grupo IV. Quanto à terapia, 73,6% não realizou adjuvância (quimioterapia ou radioterapia). Dentre os desfechos, 32,2% dos pacientes vieram a óbito relacionado à doença, 25,6% estão vivos sem a doença, 16,7% estão vivos com a doença em seguimento e 10% perderam o seguimento.
Papel dos microRNAs miR-140-5p e miR-874-3p na regulação do oncogene VEGFA em câncer de cabeça e pescoço
Authors: Marzochi Ludimila Leite , Cuzziol Caroline Izak , Possebon Vitória Scavacini , Kawasaki-Oyama Rosa Sayoko , Pavarino Érika Cristina , Castanhole-Nunes Márcia Maria Urbanin , Goloni-Bertollo Eny Maria
Published: July 2022

Introdução: O câncer é uma doença multifatorial influenciada por fatores ambientais e genéticos. A progressão tumoral, os mecanismos de plasticidade celular e o desenvolvimento de metástase são coordenados por uma rede complexa de alterações genômicas e epigenômicas, aspectos que representam um grande desafio para o diagnóstico e tratamento da doença. O fator de crescimento endotelial vascular (VEGF) é o principal responsável pela formação de novos vasos sanguíneos a partir de vasos pré-existentes, processo denominado angiogênese. O processo angiogênico desempenha um papel essencial no desenvolvimento e crescimento do tumor.  MicroRNAs (miRNAs) são pequenas moléculas de RNA reguladoras não codificantes que podem regular a expressão pós-transcricional de múltiplos genes alvo. Objetivo:  Investigar se os miRNAs hsa-miR-140-5p e hsa-miR-874-3p podem interferir na expressão do oncogene VEGFA em linhagens de CCP. Metodologia: As linhas celulares FADU (câncer de faringe) e HN13 (câncer de cavidade oral) foram cultivadas até atingirem a confluência necessária para a transfecção com os mimetizadores dos miRNAs miR-140-5p e miR-874-3p. Foram realizados três experimentos independentes, com posterior extração de RNA sendo submetido ao PCR em tempo real para análise da expressão gênica e de miRNAs. A Técnica de Western Blotting foi utilizada para a avaliar a expressão proteica.  Resultados: Após a transfecção, os níveis de expressão do miR-140- 5p (FADU - RQ= 15.620; p= 0.0121 e HN13 - RQ= 3.322; p= 3.322) e miR-874-3p (FADU - RQ= 2.871; p= 0.0313 e HN13 - RQ= 13.265, p= 0.0642) estavam aumentados, em relação ao controle negativo (RQ=1,00), confirmando a eficiência da transfecção. A expressão gênica do VEGFA foi diminuída nas células transfectadas com miR-140-5p (FADU - RQ= 0.5223; p= 0.0015 e HN13 – RQ= 0.4552; p= 0.0019) e miR-874-3p (FADU – RQ= 0.4906; p= <0.0001 e HN13 – RQ= 0.7197; p= 0.2343). Conclusão: A superexpressão do miR-140-5p e miR-874-3p levou a uma regulação negativa da expressão gênica e proteica do VEGFA em ambas as linhagens celulares analisadas.
Qualidade de vida e prevalência de sintomas em pacientes com adenocarcinoma pulmonar
Authors: Da Silva Maria Zilda Domingos , Barichello Elizabeth
Published: July 2022

Introdução: O câncer de pulmão é o segundo mais comum em homens e mulheres no Brasil, sendo desde 1985 o primeiro em todo o mundo, quanto em incidência, quando em mortalidade, cerca de 13% de todos os novos casos de câncer são de pulmão, se tornando uma das principais causas de morte evitáveis no final do século XX. O adenocarcinoma pulmonar é considerado um subtipo de câncer do pulmão de células não pequenas, que corresponde por cerca de 40% dos casos, sendo um dos tumores mais agressivos e de progressão mais rápida. Objetivos: Analisar a qualidade de vida e a presença de sintomas nos pacientes com adenocarcinoma pulmonar. Metodologia: Trata-se de uma pesquisa de abordagem quantitativa e com delineamento transversal. A pesquisa será realizada no Hospital das Clínicas da Universidade Federal do Triângulo Mineiro (HC – UFTM) no setor de radioterapia e na Unidade Dona Aparecida do Pênfigo que concentra as áreas de quimioterapia, imunoterapia e hemoterapia para pacientes com câncer, no período de oito meses. A pesquisa será feita a partir de um instrumento sociodemográfico e clínico, o instrumento de Memorial Symptom Assessment Scale (MSAS) e questionário para avaliar a qualidade de vida, o European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Os dados serão coletados de forma anônima assegurando a identidade dos participantes, além disso, a coleta somente será realizada após a aprovação pelo Comitê de Ética em Pesquisa. Os aspectos éticos serão baseados na Resolução 466/12 sobre a pesquisa envolvendo seres humanos. Resultados esperados e conclusão: No presente estudo espera-se encontrar presença de sintomas que podem estar interferindo negativamente na qualidade de vida dos pacientes com adenocarcinoma pulmonar.
Ômega-3 como terapia coadjuvante sobre os efeitos adversos da quimioterapia no câncer de mama
Authors: Delmicon Natália Ellen , Miranda Mayara Lilian Paulino
Published: July 2022

Introdução: O câncer de mama é a neoplasia que mais acomete mulheres em todo o mundo e sua incidência vem crescendo em países em desenvolvimento como o Brasil. As alterações metabólicas do câncer, somadas as questões específicas do tratamento quimioterápico, podem induzir efeitos adversos deletérios e impedir o sucesso da recuperação. Estudos clínicos sugerem resultados positivos com a suplementação de ácidos graxos ômega-3 em pacientes em quimioterapia, devido suas propriedades anti-inflamatórias, antioxidantes e antiproliferativas em diferentes tipos de neoplasias. Objetivo: Investigar os principais resultados da suplementação de ômega-3 na quimioterapia do câncer de mama. Metodologia: Foi realizada uma revisão bibliográfica de literatura com busca sistemática nas bases de dados PUBMED, SCIELO E LILACS utilizando os termos específicos. Resultados: De 563 publicações, 9 artigos foram selecionados por atenderem aos critérios de seleção. Sendo, sete estudos randomizados, um estudo observacional e um estudo prospectivo longitudinal que forneceram dados de 492 pacientes. O número de pacientes em cada estudo variou de 15 a 249 e ostratamentos associados incluíram quimioterapia adjuvante e neoadjuvante e terapia hormonal com inibidores de aromatase. Em todos os estudos, o ômega-3 foi administrado em forma de cápsula de óleo de peixe, com doses entre 1g a 4,3g/dia, com ácido eicopentaenóico (EPA) e docosahexaenóico (DHA) em diferentes proporções, por períodos entre 3 semanas a 6 meses. Esses achados incluíram redução do risco inflamatório-nutricional; redução de sintomas de impacto nutricional; redução significativa de artralgia e agente protetor contra neuropatia periférica associada aos inibidores de aromatase. Conclusão: A suplementação de ômega-3 como tratamento coadjuvante na quimioterapia, com dose a partir de 1g/dia, foi benéfica para reduzir toxicidades e aumentar a taxa de resposta ao tratamento. No entanto mais ensaios específicos são necessários para confirmar esses achados.
Avaliação molecular e fenotípica de indivíduos e famílias portadores da Síndrome de Neoplasia Hereditária Multilocus (MINAS)
Authors: Silva Sophia Mascagni , Soares Diogo Cordeiro de Queiroz , Pereira Daniele Paixão , Da Rocha José Cláudio Casali , Carraro Dirce Maria , Torrezan Giovana Tardin
Published: July 2022

Introdução: Uma pequena parcela dos pacientes portadores de síndromes de predisposição hereditária ao câncer (SPHC) apresenta variantes patogênicas em mais de um gene de predisposição ao câncer (GPC), condição recentemente descrita como síndrome de neoplasia hereditária multilocus (MINAS) e com implicações clínicas ainda desconhecidas. Objetivo: O presente estudo tem como objetivo descrever as características clínicas de pacientes/famílias com MINAS e avaliar características moleculares dos tumores desses indivíduos, buscando definir relações de etiologia entre variantes e tumores, efeitos sinérgicos e riscos modificados nesses indivíduos. Metodologia: Foi realizada coleta de dados clínicos, histopatológicos e de histórico familiar de 27 pacientes portadores de MINAS identificados na casuística do A.C.Camargo. Estão sendo realizadas análises de co-segregação em familiares com câncer e, em material tumoral, análises de perda de heterozigose (LoH) através de NGS de amplicon. Resultados: Observa-se um predomínio de pacientes mulheres (22/27) e com histórico de câncer de mama (14/27) e prevalência de síndrome de câncer de mama e ovário hereditários (HBOC). Os genes com variantes patogênicas/provavelmente patogênicas identificados em um maior número de pacientes foram: BRCA2 (13), MUTYH (6), BRCA1 (5), CHEK2 (5), TP53 (3). Sessenta e quatro por cento dos pacientes apresentam variantes em dois genes de herança autossômica dominante, 30% apresentaram 1 gene de herança autossômica dominante e 1 de autossômica recessiva (monoalélico) e 7% apresentaram variantes em dois genes de herança autossômica recessiva (monoalélico). Os resultados preliminares de perda de heterozigose demonstram que houve perda somática do alelo selvagem por deleção em 3 dos 5 tumores avaliados, nos genes BRCA1, BRCA2, ATM. Conclusão: Esperamos descrever as consequências fenotípicas clínicas e moleculares de um grupo raro de pacientes portadores de MINAS, colaborando para o conhecimento científico da área e contribuindo com o banco de dados de MINAS.
Composições em matilha: potência coletiva que produz resistências e cria movimentos inventivos curriculares
Authors: Werneck Hociene Nobre Pereira , Silva Sandra Kretli da
Published: July 2022

Esta obra trata de uma pesquisa que, ao potencializar a emergência de novos modos de composição e experimentações com professoras e crianças, defende as composições em matilha e o devir-lobo não como metáfora, mas como modo de problematizar a potência do trabalho coletivo no cotidiano escolar, constituindo-se como forças de resistência que, ao fazer o currículo uivar, criam movimentos de invenções curriculares. Ao defender uma educação pensada “com” as matilhas, aposta-se na concepção de currículosmatilhas vividos/produzidos em meio às multiplicidades de conhecimentos, linguagens, afetos e afecções que circulam em redes de conversação e ações complexas nos cotidianos escolares e se constituem como corpos coletivos. A obra argumenta em prol da expansão da força de ação coletiva na/da escola, não como ajuntamento de pessoas para um trabalho coletivo homogêneo, mas como uma organização que leva em conta as multiplicidades, a diferença e a constituição de um comum plural.
Impact of Social Media Advertisement on Youth
Authors: Kumar Kesharwani Pramesh
Published: July 2022

The Indian advertising industry has emerged as one of the major industries and has broadened its horizons in the field of marketing. The creative minds of the Indian advertising industry have come up with challenging concepts and works that are termed as works of art especially in the field of advertising. With the huge innovative development of electronic media, advertising has grown as an organized industry. With the advent of radio, television, print and internet it has been able to gain much potential. Consumers generally do not realize just how influenced they are by advertisements. They do not understand that most advertising messages are created depending on their strategic thinking. Identifying an essence, an emotion which makes people crave for a product or service is what most advertisers do. If an advertisement is able to tap into meaningful emotional, psychological or sociological factors, more often it can result in success. Advertising technique is beginning to move viewers from the traditional outlets to the digital ones. Earlier marketing of products were done with banners and hoarding advertisements, which then grew to television broadcasts and now with the maximum usage of the internet, advertising arc is moving towards online. The rapid growth of the internet has a strong impact on the worldwide marketing environment. Moreover, the internet as a medium plays an important role in attracting customers because of its flexibility and interactivity. Currently it has become one of the most popular approaches for business and consumers to perform trade over the internet. Penetration of social networks in the 1990's has changed our societies communication patterns and also the relations among people. Advertising is one of the most powerful and efficient modes of mass communication and the purposes are to bring awareness of the advertised products and provide information that will assist consumers to make purchase decisions. It has the power to persuade consumers to purchase products, by influencing attitude and behaviour intention.
Indian Higher Education: Causes of Deterioration in Quality and Measures of Improvement
Authors: Pandey Mahesh , Singh Sachin , Singh Govind
Published: July 2022

Indian higher education system is the third largest higher education system in the world. The failure and success of any nations depends on their human resource. The improvement of human resource is the responsibility of higher education system of any country. In this paper we have discuss on causes of deterioration in quality and measures of improvement in Indian education system. In this paper we have limited ourselves to mainly qualitative lag. Because today we are facing serious quality crisis in our education system.
Superphanes: Facile and Efficient Preparation, Functionalization and Unique Properties
Authors: He Qing
Published: July 2022

Superphanes, compounds in which the two benzene rings clamped parallel on top of each other by six bridges, have been attracting considerable interest because of their structural beauty and symmetry. However, progress in
the research of superphane chemistry and beyond has been seriously hampered by their poor availability. Herein, we report the facile and scalable synthesis of a collection of superphanes with structural diversity and their unique
photophysical properties, as well as their unusual host–guest behavior. A set of secondary amine–linked superphanes are obtained via dynamic self–assembly of a hexakis–amine and various readily derived aromatic dialdehyde in one pot, followed by in–situ reduction with NaBH4. Further post–functionalization was exemplified by secondary amine to tertiary amine conversion. All superphanes under study were found to exhibit interesting
fluorescence either in solution or in the solid state. Finally, the unusual host–guest binding properties was exemplified by the stabilization of a labile 2Cl–⋅H2O cluster with fully protonated 6a both in solution and in the
solid state. With the easy and versatile synthesis, modification, as well as unique photophysical and host–guest properties reported herein, we believe that this study offers new possibilities for superphane chemistry, supramolecular host design, advanced functional materials and beyond.
Race and Power in Pullman Car Hiawatha
Authors: Gerland Oliver
Published: July 2022

This article describes a successful experience teaching Wilder’s Pullman Car Hiawatha to theater graduate students at the University of Colorado Boulder. Students read the play alongside Bertolt Brecht’s The Exception and the Rule and Langston Hughes’s Don’t You Want to be Free? They prepared a comparative analysis of the three plays, and then the author turned their attention to the character of Harrison, a Black man who serves as the Pullman car porter. The author outlined the major role that Pullman car porters played in civil rights struggles in the United States and observed that Wilder puts Harrison in charge of the stage near the end of the play. In discussion, students found other representations of race and power in the play; notably, these included Wilder’s allusion to histories of Native American displacement. They also explored perspectives drawn from ecocriticism, disability studies, and critiques of modernity.
Mozart and the Gray Steward in the College Classroom
Authors: Hallquist Terryl W.
Published: July 2022

Mozart and the Gray Steward, an early one-act play by Thornton Wilder, facilitates creative study of theater direction in the college classroom. Rife with potential, this obscure, very short play stimulates imagination and learning in the areas of dramaturgy, character analysis, style, casting, design, staging, and pacing. The exploration of links between Mozart and the Gray Steward and Wilder’s early letters and life experiences and reflections of both in his mature work promotes understanding of the interconnection between an artist’s life and his creativity for undergraduate students close to Wilder’s age when he wrote the play. Such dramaturgical research fosters discussion about character analysis as well as casting, leading to meaningful practice in staging and character development as students workshop scenes. Exploring a director’s relationship with a design team, informed by the aesthetic of the playwright, is another of the benefits of this sort of research. Because the plot seesaws between realism and nonrealism, this hitherto uncelebrated Wilder one-act provides a valuable opportunity for classroom discussion of pacing, staging, and other stylistic issues in an undergraduate directing curriculum.
What I Learned from Our Town
Authors: Hecht Stuart J.
Published: July 2022

In 2018 the author received an unexpected Facebook message from former cast members of his 1988 production of Our Town, celebrating the thirtieth anniversary of their production. The author was moved but also wondered about the educational dynamics of Thornton Wilder’s play, as well as how his directorial methods reflect his pedagogical beliefs. In 1988, it was fifty years since the first performance of Our Town in 1938; in what ways had the play, as well as America itself, changed over those years? Was Wilder’s iconic play still relevant? Could it stand up to such scrutiny? In this article, the author describes that his goal, inspired by Peter Brook, was to enhance the play’s immediacy, not alter it. The author's artistic process resulted in changing the play’s setting from the 1910s to the 1950s. The author used dramaturgical and improvisational techniques to explore the world of the play and find fresh solutions. Did the play hold up to such treatment? This article shows that Wilder proved as much teacher as playwright.
FLOW SLIDES: THE ROLE OF THE COMPOSITION OF SOIL MASSIF IN THEIR FORMATION, DEVELOPMENT FEATURES AND TYPICAL TYPES
Authors:   Lomonosov Moscow State University, Zerkal O.V.
Published: July 2022

The flow («dry», plastic, viscoplastic, viscous) is one of the main mechanisms of landslide displacement. The paper discusses the features of the formation and development of landslides, the displacement of which occurs in the form of a flow caused by soils saturated. The flow slides formation is associated with the excess of the creep threshold by the shear stresses acting in the slope massif with the transition of deformations from decaying to irreversible, progressive ones. When classifying slope processes, most researchers classify flow slides (under various names) into a separate class. Flow slides usually refer to the displacement (in subaerial or subaqueous conditions) of the moist mass or saturated clay, sandy-clay or rubble-clay soil, which moves along an inclined surface. It is shown that the formation of flow slides can occur either for a long time, with the gradual development of plastic deformations, or very quickly, with an almost instantaneous transition of soils to a fluid state (liquefaction). The main features with reference to which typical types of the flow slides is carried out are: 1) the capture depth of the massif by landslide deformations and the location of the flow zone; 2) morphometric characteristics, including the shape of the landslide body (in plan); 3) the type of soils involved in displacement and the mechanism of the transition of soils into a «fluid» state; 4) features of the displacement mechanism, including depending on the consistency of the landslide masses, due to the ratio in the composition of the moving mass of the solid (debris, clay) component and the water component. The features of the development and differences of surface landslides and «deep» flow slides, including the features of their displacement, morphology and structure, are characterized. The sequence of the landslide deformations development is described. The existing approaches to the typification of flow slides are considered. Summary typical types of flow slides of a current on the initiation and mechanism of displacement is prepared. It is concluded that it is necessary to take into account the features and differences of flow slides in the course of their study.
SOIL MASSES OF THE KHARASAVEY FIELD AS AN OBJECT FOR THE CREATION OF UNDERGROUND STORAGE CAVITIES OF DRILLING WASTE
Authors:   Lomonosov Moscow State University, Mosina A.S.
Published: July 2022

The article provides the typification of the soil masses of the the Kharasavey field according to the composition, structure and condition of permafrost soils. The characteristics of composition, structure and condition that have the greatest impact on the stress-strain state of permafrost soil mass were used. Based on the typification, the favorable soil masses for the construction and operation of underground storage cavities for disposal of waste drilling were identified. This approach can be extended to other areas of the permafrost zone.
El perfil de la desnutrición infantil en Imbabura y el rol de las políticas públicas
Authors: Rivera Jairo
Published: July 2022

La desnutrición infantil limita el progreso de las sociedades y a pesar de las notables reducciones de sus prevalencias en el tiempo, el Ecuador tiene una situación crítica para su nivel de desarrollo. El objetivo de la investigación es caracterizar a la desnutrición infantil en Imbabura, su progreso en el tiempo y el rol de las políticas públicas. La metodología es mixta, con métodos cuantitativos del modelo probabilístico con pooling data y métodos cualitativos de revisión documental, utilizando las Encuestas de Condiciones de Vida 1999, 2006 y 2014, y los planes de desarrollo y ordenamiento territorial, respectivamente. Entre los principales resultados se encuentra que Imbabura ha logrado una reducción superior al promedio nacional, con distintas prevalencias entre los grupos de la población
Dynamic Simulation of a Reactive Distillation Column for Ethyl Acetate Production: Optimization of Operating Conditions Using Response Surface Methodology
Authors: ALDEMİR Adnan , ERSİNGÜN Dilan , BAYRAM İsmail
Published: July 2022

In this study, we aimed to determine the optimum operating conditions for the production of ethyl acetate (EtAc) through the esterification of ethanol (EtOH) with acetic acid (HAc) in a reactive distillation (RD) column. For this, the designed column was simulated for the production of EtAc. HAc flow rate, EtOH flow rate, HAc feed stage, EtOH feed stage, reflux ratio, and reactive feed temperatures were changed and the effects of these parameters on EtAc production were observed. Central Composite Design was employed to define the optimum operating conditions for the RD column. The determination coefficient R2 was equal to 0.9197 suggesting a good relationship between the predicted and simulated responses. Adjusted R2 and predicted R2 values obtained from the program were 0.8823 and 0.7956, respectively. The optimal conditions for the EtAc production response were HAc flow rate of 120.00 kmol/h, EtOH flow rate of 150.00 kmol/h, HAc feed stage 6, EtOH feed stage 14, reflux ratio 2.2, and feed temperature 70.28 °C, which were designated by the maximum desirability function.
مستوى اكتساب طلبة بعض مؤسسات التعليم العالي بسلطنة عمان لمهارات القرن الحادي والعشرين في ظل جائحة كورونا
Authors: المقيمي فاطمة , المغيرية يسرى , البوسعيدي أحمد
Published: July 2022

هدفت الدراسة الحالية إلى تعرف مستوى اكتساب طلبة بعض مؤسسات التعليم العالي بسلطنة عمان لمهارات القرن الحادي والعشرين في ظل جائحة كورونا من وجهة نظرهم خلال العام الدراسي 2021- 2022، والكشف عن الفروق الإحصائية حول درجة تقدير عينة الدراسة لمستوى اكتسابهم لتلك المهارات تبعا لمتغيرات: نوع الجامعة، والتخصص العلمي، والتوصل إلى إجراءات مقترحة لتطوير مستوى اكتساب الطلبة لمهارات القرن الحادي والعشرين بسلطنة عمان في ظل هذه الجائحة. وقد تمثل مجتمع الدراسة من طلبة جميع مؤسسات التعليم العالي بسلطنة عمان؛ وتكونت عينة الدراسة من (101) طالبا وطالبة بالطريقة الميسرة وفقاً لاستجابتهم على الاستمارة الالكترونية المعدة باستخدام (Google Forms)، حيث تم استخدام المنهج الوصفي المسحي من خلال تطوير استبانة مكونة من أربع مجالات وهي (التفكير والابتكار، الاتصال والتواصل، الثقافة التكنولوجية والمعلوماتية، والشراكة والتعاون ) تضمنت (40) عبارة لجمع البيانات من أفراد عينة الدراسة وتحليلها باستخدام برنامج الحزمة الإحصائية للعلوم الاجتماعية (SPSS). وتم التوصل إلى مجموعة من النتائج أهمها: أن تقديرات أفراد عينة الدراسة من الطلبة لمستوى اكتسابهم لمهارات القرن الحادي والعشرين في مؤسسات التعليم العالي بسلطنة عمان من وجهة نظرهم جاءت بمستوى كبير. ولا توجد فروق ذات دلالة إحصائية بين متوسطات استجابات أفراد العينة تعزي لمستوى اكتساب طلبة مؤسسات التعليم العالي بسلطنة عمان لمهارات القرن الحادي والعشرين وفقا لمتغير التخصص العلمي (علوم تطبيقية، وعلوم إنسانية) ونوع الجامعة سواء أكانت حكومية أو خاصة.
Exploitation of construal operations in evaluating poetic translated works
Authors: Harbi Dhaifullah Zamil , Abdulkareem Mustafa Abdulsahib
Published: July 2022

Poetic translation is one of the most debatable areas in translation and applied linguistics. It is not an easy task to translate a poetic text because of peculiarity and cultural aspects of poetry. Therefore, how one can evaluate a poetic translation is an applied linguistic area that deserves to be studied. Cognitive Grammar (CG) has provided the field of linguistics with a new perspective by relating language to all other human cognitive activities and faculties. Recently, this grammar provides literature with different tools that can be used in literary analysis. Construal operations are among these tools that can play a role in literary analysis. The basic question of this paper is: can construal operations play a role in evaluating poetic translations? To what extent Middleton and Garza-Falcón (1993) succeeded in translating Ibn Zaydún's Poem "Al-Zahara"? The fundamental aim of the current work is to employ construal operations in evaluating poetic texts and to evaluate the English translation: Ibn Zaydún's Poem "Al-Zahara". It is hypothesized that construal operations play a role in the evaluation of poetic translation. Regarding Al-Zahara, it is assumed that the translation maintained the general aspect of the original text, but it is not accurate in many places.
Biosynthesis and antibacterial activity of Passiflora incarnata mediated copper oxide nanoparticles
Authors: Tassew Molla Fentie , Chouhan Garima
Published: July 2022

Plant mediated nanoparticle synthesis is a rapidly growing field of study around the world. Plant biomolecules make non-toxic, stable, and cost-effective copper oxide nanoparticles In this study, eco-friendly CuONPs were prepared through a biosynthetic approach using Passiflora incarnata L. leaf extract. The synthesized CuONPs were characterized using UV-Visible spectroscopy (UV-Vis), scanning electron microscope (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Dynamic light scattering (DLS). Furthermore, the antibacterial activity was evaluated against Listeria monocytogenes. The SEM results indicated that rod-shaped CuONPs with an average particle size of 49.8 nm (size range of 39-63 nm) were synthesized and shown good antibacterial activity against Listeria monocytogenes. CuONPs produced from Passiflora incarnata leaf extract could be a potential antibacterial agent for treating foodborne infections caused by Listeria monocytogenes. However, more research is needed to determine how it works on the target microorganism.
use of high-performance liquid chromatography technique for the simultaneous determination of amlodipine and valsartan
Authors: Nawfal Imad Najm Khudair , Hanon Imad Tarek
Published: July 2022

This technique was used in the estimation of amlodipine and valsartan simultaneously. The method was sensitive and accurate, and the estimation was done in a short time. In this work, a separation column of type L1, 150 mm was used to separate and sold. The group also found the ultraviolet spectrophotometer that used a wavelength of 239 nm, the temperature of the column was 40 degrees Celsius, and the mobile phase, consisting of 50:50 (acetonitrile: methanol: drops of triethylamine, pH = 2.4) was long. Through what was reached, we find that the method is sensitive, accurate and medium in size (101.43-99.13) and (100.17-99.53), and linear punches (6-14 mcg/ml) and (48-112 mcg/ml) for the two drugs, respectively. The method was applied to a number of pharmaceutical preparations available in the local market, successful in the real-time quantification of amlodipine and valsartan, respectively.
Study of the impact of civil waste on the chemical, physical and biological content of the Tigris River within Samarra
Authors: Fattah Mardin Ali Abbas , Khaleel Rana Ibrahim , Nijris Osama Nadhom
Published: July 2022

This study included the selection of three stations, two of which are on the Tigris River passing through Samarra and the other station representing the household wastewater - Samarra, and the duration of the study was six months from October 2021 to March 2022. The study included knowledge of the chemical, physical and biological properties of the domestic wastewater plant and river water and the observation of domestic wastewater on the water quality of the Tigris River. Chemical agents included pH, dissolved oxygen, and the bio requirement of oxygen, while physical factors included air temperature, water temperature and total dissolved salts. Results showed that pH values tended to be base,  ranging from 6.6 - 8.7, dissolved oxygen showed converging values ranging from 3.8-9 mg/L, and the bio-oxygen requirement values ranged from 0.8-8 30 mg/L, the air temperature ranged from  7-32°C, the water temperature ranged from  5-26°C, and the total melt salt values ranged from 210°C  - 1380 mg/L, total number of air bacteria (TPC) ranged between (0.06 – 74000*) cell/mL .
Assessment of some physical and chemical properties of the Tigris River water passing through Al-Dour District
Authors: Kamil Marwan Abdulrazzaq , Erdeni Abid Ahmed , Zangana Ashraf Jamal Mahmoud
Published: July 2022

The current study was conducted on the course of the Tigris River passing in the district of Al-Dur / Salah Al-Din Governorate, with three stations distributed along the distance of the study area, for the period from the beginning of November 2021 until April 2022. The first station ST1 is located near the water purification project of Al-Bu Ajil area and the station The second station, ST2, is located at the crossing, and the third and last station, ST3, is located near the Al-Dour silo. The study included the measurement of some physical factors (air temperature, water temperature, electrical conductivity) and some chemical factors (pH, total hardness, calcium ion, magnesium ion). The results showed that the air temperature ranged between 12-22°C, while the water temperature ranged between 8-20.5°C. As for the electrical conductivity, it recorded values ​​between 499,54-679.45µs/cm, while the pH values ​​were neutral. Its levels ranged between 7.34-8.04, and the total hardness may have been affected by the geological characteristic of the land on which the water flows in the stations, and it was found that its water is hard, which may be mostly caused by the bicarbonate ion.
Synthesis of new Schiff bases derivative of benzoin compounds
Authors: Mohamned Moayd. N. , Jawad Mustafa. H.
Published: July 2022

In this In this research study a different chain of schiff bases starting benzoin 4,4-dimethyl benzoin/4,4-dichloro benzoin/ 4,4-dibromo benzoin/4-chloro-4-dimethylamino benzoin/4-methyl benzoin with 1)Alanine yield series of new schiff bases, the structure of the compound was determined on the bases of their FT-IR,1HNMR and C.H.N. the pureness of the created compounds were tested via the antibacterial action were estimated by paper disc dispersal technique.
Exploring the cultural dimension of technological behaviour in the Indian context
Authors: Agarwal Richa N.
Published: July 2022

Digital storm which has taken the world has changed the way organisations function. It has brought in a huge change in the way organisations sell and transact. In case of India major change in the e-payment started after demonetization (change of national currency) happened. It is when people were forced to transact through cashless methods in shortage of cash. First time small merchants did business through cashless methods. Though, small merchants still avoid digital methods and prefer cash transaction. Present study was done to understand the factors which influence the behavioural intention of small merchants for adopting cashless methods. The UTAUT (Unified theory of acceptance and use of technology) model was used. It was also to find whether the model can be applied in the Indian context.The study found that the independent factors of social influence, perceived value, trust did not impact the behaviour intention of small merchants. Though these factors are quite relevant in the Indian cultural context. Thus, the UTAUT model was not found quite suitable to study the behavioural intention of the small merchants in the Indian markets.
Different comparison of mean SR. homocystene in serum 25 – hydroxyvitamin D in acute stroke
Authors: Padmini Sahu , Sahu Y. P. , Gujaram Marandi , Dhone Pravin G.
Published: July 2022

The active form of vitamin D is 1,25 dihydroxy vitamin D. Renal and many extra renal tissues are able to synthesize 1,25 dihydroxy vitamin D on a local and intracellular level. Local tissue level of 1,25 di-hydroxyvitamin D is determined by concentration of circulating 25(OH) vitamin D level. Stroke is a common worldwide health problem. It is a major cause of morbidity, mortality and disability in developed as well as developing countries. Both vitamin D deficiency and stroke are very common in urban and rural India. Hence this study was designed to evaluate the association of vitamin D deficiency in acute stroke. This study shows the different comparison of MEAN SR. HOMOCYSTENE in serum 25 – hydroxyvitamin D in acute stroke and found to be in total serum homocysteine levels were 19.64 micro mole/l in cases than 10.1 in control   However the difference was statistically highly significant (p<.0002).
Effect of colostomy empowerment program for mothers on occurrence of peristomal skin complications among their infants
Authors: Mohamed Afkar Ragab , Mohamed Soheir Abd-Rabou , Abouelfadl Mohamed Hamed , Kamel Walaa Mohamed
Published: July 2022

Colostomy is often a life-saving procedure but is still associated with significant morbidity. Aim of the study: To evaluate the effect of colostomy empowerment program (CEP) for mothers on occurrence of peristomal skin complications among their infants. Design: Quasi -experimental design was utilized. Sample: A convenient sample of 60 infants undergoing colostomy operation and their mothers. Setting: The current study conducted in three settings at Cairo University Specialized Pediatric Hospital (CUSPH) (surgical neonatal intensive care unit, in-patient surgical unit, and the out-patient surgery clinic).Tools for data collection: Tool I structured interview questionnaire; Tool II mothers’ knowledge and reported practice assessment sheet pre-posttest; Tool III observational checklist and tool IV complications recording sheet. Results: There were statistically significant differences regarding total mean score of mothers' knowledge, reported practice and skills in both groups. Peristomal skin complications were higher in the control group. Conclusion: The current study concluded that after CEP, there was a significant improvement in the level of knowledge, reported-practices, and skills among mothers in the study group. Infants in the study group were exposed to less postoperative complications regarding peristomal skin complications than infants in the control group.
The dark side of Galamsey
Authors: Fening P. A. , Adala C. E. , Agyei I. K. , Quashie R. T.
Published: July 2022

Illegal small-scale mining popularly referred to in Ghana as ‘Galamsey’ has been a serious menace to the society and the environment. Since gold is one of the most valuable natural mineral resources in the country, and legal mining is accompanied by a lot of rules and regulations, a lot of individuals in a bid to get rich quick find dubious means to dig for it. The media houses have stressed the effects of galamsey on the environment. However, it has not made much impact. This paper focused on constructing a metal sculpture to depict the negative effect of galamsey on the environment. It, therefore, adopts the arc welding technique by using metals and scraps to create a conceptual metal sculpture to educate the public about the effects of Galamsey on the environment. Studio-based research method was used for the study. The project was successful and the results were analyzed under the social, philosophical, artistic and intellectual contexts. The finished work was titled “Ɛnkum yƐn wiasi”, an Akan expression which means “Don’t kill Our World.
Implications of digitalization during the COVID-19 pandemics
Authors: Dzuráková Daniela
Published: July 2022

The article provides with analysis of the proposal of Regulation on European Digital Identity with regards to processing of personal data, particularly those that concerns health. It presents cross-examination with the Mobile Tracing Application and Digital Green Certificate which were established in order to combat the COVID-19. Lastly, it mentions the main challenges and critical positions, as well as proposals on how to tackle some of them.
To what extent might (and should) the competition law apply to public authorities?
Authors: Petr Michal
Published: July 2022

Even though public authorities, in particular the Government and the municipalities, may dis-turb effective competition by their exercise of public powers, competition law does not apply to them, except for the specific and limited circumstances when it can be used in connection with other Treaty provisions. This article first explores the limits of applicability of EU competition law on public authorities; it concludes that even though EU competition law as such does not provide protection against the conduct of public authorities that distorts competition, its scope should not be expanded. The aim of competition law is to limit market power, not official au-thority. Instead, after discussing the legislation of selected countries from Central Europe, it is put forward that specific domestic legislation, applied by competition authorities, may provide an effective remedy to this problem. As comparative research of these issues has been rather limited so far, further elaboration of this topic is recommended.
European administration of consular protection
Authors: Csatlós Erzsébet
Published: July 2022

This paper seeks to review the evolution of consular protection management in the European Union. The process of Europeanisation has reached its current profile through three stages of evolution and we are likely to see further institutionalisation, with several available alternatives. The historical analysis outlines the rationale for a further process of Europeanisation in the light of changes in the legislative powers of the EU, exploring the nature of legal regulatedness and aligning it with the development of fundamental rights, and presents a prognosis for the next stage of development in the light of experience to date. The research findings, based on an analysis of normative rules of various origins, regulatory and binding, preparatory documents, official statistics and reports as primary sources, and literature on specific aspects of the subject, also suggest that an effective consular protection policy will require changes in the tasks and competences in the next development stage. The existing consular enforcement apparatus in the Member States should be better integrated with the network of EU delegations, at least for some of the specified consular protection tasks. This raises further regulatory issues, but it is undeniable that the Europeanisation of consular protection administration is moving in this direction.
Additions to the genus Eragrostis P. Beauv. of Hamirpur (including Mahoba) district, U.P. India
Authors: Narain Satya
Published: July 2022

A taxonomic account of the genus Eragrostis P. Beauv. of family Poaceae in Hamirpur (including Mahoba) district U.P. with up-to-date nomenclature, key for identification, brief description, phenology and ecology of each taxon is provided. The genus in the district is represented by nine species of which seven species are new additions to the district.
Types of Energy in Nover Top Graphs
Authors:   Vel Tech Rangarajan Dr. Sagunthala R D Institute of Science and Technology, Chennai, G.Muthumari G ,   narmadadevi23@gmail.com, Devi R.Narmada
Published: July 2022

Energy of graphs plays a vital role in the field of application in energy. Neutrosophic over top graph theory is more efficient and accurate results than other existing methods. In this research study, we present concepts of Energy, Laplaican energy and Signless laplacian energy in Nover top graphs. Describe some of their properties, develop relationship among them and their application.
Severe Arrhythmia Caused by Abscess Endocarditis on a Bicuspid Aortic Valve: Case Report and Literature Review
Authors: H Bendahou
Published: July 2022

The incidence of infective endocarditis (IE) on the bicuspid valve is high with serious complications. Perivalvular extension is one of the most serious complications because it can be complicated by conduction disorders such as AV block or bundle branch block or rhythm disorders, often with a poor prognosis. We report a rare case of infective endocarditis in a bicuspid aortic valve complicated by perivalvular abscess and trifasicular block.