bluuebunny/crossref_metadata_2025 huggingface dataset:
Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling -
A Review
Authors: Berrichi Amina , Bachir Redouane , Bedrane Sumeya
Published: June 2023

Different intermediates are key molecules to synthesize high-added value bioactive
and pharmacology molecules such as propargylamines may be synthesized in several ways using
catalysts in homogeneous and heterogeneous conditions. This review presents the catalysts
which are used in the A3, AHA, and KA2 coupling reactions to afford propargylamines. It also
provides a classification of all the propargylamines known up to date in the literature and their
reported synthesis conditions.
Nutritional and Medicinal Values of Mushroom
Authors: Tabassum Nazish , Prasad Singh Mohan
Published: June 2023

Humans have ingested both wild and farmed mushrooms for their nutritional
and therapeutic properties. Mushrooms are a good source of protein, carbohydrates,
and dietary fiber compared to energy and fat. They are rich in vitamins like riboflavin,
niacin, and folates, as well as minerals and trace elements like potassium and copper.
Due to their distinct flavor, they have been eaten as food for ages. Aside from being a
nutrient-dense diet, certain mushrooms are also considered a rich source of
physiologically active chemicals with potential therapeutic value in Chinese medicine.
Phenolic chemicals, sterols, and triterpenes are examples of bioactive secondary
metabolites that occur in mushrooms. Mushrooms are essential in traditional medicine
for their healing powers and characteristics, as well as their long history as a food
source. It has been shown to have positive benefits on health and the treatment of
certain ailments. Mushrooms have a variety of nutraceutical qualities, including the
prevention or treatment of Parkinson's disease, Alzheimer's disease, hypertension, and
stroke risk. Due to their antitumoral properties, they are also used to lower the
likelihood of cancer invasion and metastasis. Mushrooms are antimicrobial,
antioxidant, immune system boosters, and cholesterol-lowering agents, and essential
bioactive compounds. Mushrooms and mushroom derivatives may have health benefits
if included in our daily diet.
Application of Mushroom in Bioremediation of Toxic Heavy Metal Ions
Authors: Ahmed Ghufran , Kumar Tiwari Ritesh , Kumar Pandit Gaurav , Shanvi  , Verma Manisha , Singh Veer , Prasad Singh Mohan , Singh Meenakshi
Published: June 2023

Heavy metals have economic importance in industrial applications and are
presently becoming a significant environmental concern. Components of heavy metals
like As, Cd, Cr, Pb, Se, and Hg are considered systemic toxicants and induce various
organ damage even at lower levels of exposure. Natural sources include metallurgy of
metal-bearing rocks and volcanic eruptions, whereas mining and different industrial
and agricultural operations are human sources to release them into the environment. In
recent times, remediation of toxic metal pollution has been a major environmental and
technological challenge all over the world. Several physiochemical strategies have been
used in the past to remove heavy metals from the environment. But, it has adverse
repercussions, including power dissipation, incompetence for inherently dangerous
ions, pernicious by-products, and high cost; hence, alternative strategies are necessary.
Biosorption and its operational processes have been very effective in the removal of
hazardous heavy metals and display features like eco-friendly, high efficiency, and
economic viability, and can be used repeatedly, showing selective metal binding,
effective desorption, and recycling of adsorbents. Different biological agents like algae,
bacteria, fungi, and yeast can be employed to carry out bioremediation, especially
mycoremediation. The potential of fungal biomass (Mushrooms) as a biosorbent is well
accepted for the removal of toxic heavy metals and radionuclides from the environment
because of its excellent metal-binding characteristics and tolerance towards metals and
unfavourable environmental conditions like diverse pH and temperature conditions.
Mushrooms, macro-fungi, have fruiting bodies that grow out of a mass of mycelium
and can build up heavy metals in high concentrations in their bodies above maximum
permissible concentrations and may also act as an effective biosorption tool. High accumulation potential and shorter life span are some of the advantages of using
mushrooms as biosorbents and exhibiting excellent mycoremediation potential.
Design A Resilient Network Infrastructure Security Policy Framework
Authors: Bhardwaj Akashdeep
Published: June 2023

The information security policy development lifecycle tends to lack focus on
the use of standard terms and semantics. This results in blurred outlines for monitoring,
evaluation, and enforcement of the security policy for the employees confusing
adhering to and implementing it, which leads to a lack of a process of publishing from
the security policy, end-user awareness, translation of high-level policy to lowest level
component configuration plans and actions to take in time of crisis. This leads to the
critical need to design an empirically tested, comprehensive security policy. This
chapter proposes bridging the gap between the high-level information security policy
descriptions and low-level network infrastructure security implementation. With new
and innovative technologies, such as Cloud, Remote Computing, Enterprise Mobility,
and e-commerce on the rise, network security has remained an ever-increasing
challenge. This chapter presents a security framework to bridge the gap between high.level specification requirements and the low-level implementation phase for network
infrastructure security using the network architecture model with the security policies
associated with the network components required to be enforced. An architectural
model and a set of design-level security policies are considered to achieve the
framework design. Also discussed are the advantages and desired characteristics of the
model, relating to existing processes worked in the design area, and future research
directions are pointed.
Security Algorithms For Cloud Computing
Authors: Bhardwaj Akashdeep
Published: June 2023

With growing awareness and concerns regarding Cloud Computing and
Information Security, there is growing awareness and usage of Security Algorithms in
data systems and processes. This chapter presents a brief overview and comparison of
Cryptographic algorithms, with an emphasis on Symmetric algorithms should be used
for Cloud-based applications and services that require data and link encryption. In this
chapter, we review Symmetric and Asymmetric algorithms with an emphasis on
Symmetric Algorithms for security consideration on which one should be used for
Cloud-based applications and services that require data and link encryption.
Assessing Transit Oriented Development (TOD) Elements at Earlier-Built Transit Stations
Authors: Abdullah Yusfida Ayu , Yakob Hamizah , Khalid Nurul Shakila , Andi Andi
Published: June 2023

Urban inaccessibility is part of urban transportation issues. TOD is a solution to promote accessibility, and land use planning is part of TOD principles. This paper shares the outcome of a study that focuses on the interrelationship of land use and TOD and evaluates the core areas of two earlier-built transit stations before TOD was put forward in Malaysia. Thematic analysis was employed together with site investigations, and results demonstrated the essential requirement of integrating land use planning in TOD and the performance of two transit stations which embrace some of the critical principles of TOD.
АТИПОВИЙ ВАРІАНТ ПЕРВИННОГО ГІПЕРПАРАТИРЕОЗУ: КЛІНІЧНИЙ ВИПАДОК
Authors: Шептуха Сергій , Губар Олександр
Published: June 2023

В статті описаний клінічний випадок діагностованого та вилікуваного атипового за лабораторними показниками первинного гіперпаратиреозу у пацієнта 1981 року народження. В анамнезі пацієнт лікувався у багатьох лікарів різних спеціальностей, але лише сьомий уролог запідозрив наявність пухлини прищитоподібної залози. Виконано оперативне втручання, що призвело до значного покращення самопочуття та нормалізації показників кальцієво-фосфорного обміну. Особливістю випадку є нормальний рівень кальцію іонізованого до та після оперативного втручання. Тому, за наявності клінічної картини гіперпаратиреозу та/або його ускладнень доцільно обов’язкове серійне визначення рівня паратгормону, кальцію загального та іонізованого в крові.
Development of a novel microdevice for sorptive extraction under a green analytical chemistry approach: Application for bioanalytical determination of Ibuprofen
Authors: Riera-Williams Jessica P. , Ponce-Rodríguez H.D.
Published: June 2023

This study proposes a novel device called micro polymeric magnetized bar adsorptive extraction (µ-PMBAE), as an extraction and enrichment technique for trace analysis in aqueous samples. These micro-bar absorbent devices were prepared using easily accessible and low-cost materials, incorporating different sorbent materials into a polymer and introducing a small piece of neodymium magnet. Several stability tests were applied to determine their robustness, stability, and weight variation; finally, ibuprofen concentration in urine samples was determined, demonstrating the applicability of extraction devices under a green analytical chemistry approach. The µ-PMBAE showed remarkable advantages since different sorbents can be added to the hot melt glue. This tunes the interaction with the analytes to become more specific in the extraction. Likewise, the magnetic ability makes it possible to carry out extraction without using an extra stir bar, matching its performance with the traditional commercially based on polydimethylsiloxane phase. The proposed analytical method demonstrated excellent performance concerning high recovery percentages, adequate coefficients of variation, and low detection limits.
Mobile Empowerment: Enhancing Education and Connectivity for College Students
Authors: Tamilarasi M.
Published: June 2023

Mobile phone usage among college students aged 18 and above, offers various benefits. Firstly, mobile phones provide convenient communication tools, allowing students to stay connected with peers, family, and faculty. Additionally, access to vast information through the internet aids research and learning beyond the classroom. Educational apps and resources enhance learning experiences and foster creativity. However, several issues accompany mobile phone use. Distraction from notifications, social media, and addictive nature can hinder academic performance. Excessive screen time may negatively impact physical and mental health, leading to sedentary lifestyles and mental health concerns. Misuse can result in cyberbullying, exposure to inappropriate content, and privacy risks. To address these concerns, establishing guidelines and educating students on responsible usage is crucial. Implementing policies that regulate usage during instructional time helps minimize distractions and promote focused learning environments.
НЕЙТРОННЫЙ СПЕКТРОМЕТР-­ДОЗИМЕТР НОВОГО ПОКОЛЕНИЯ
Authors: Руднев П. , Чешигин И.
Published: June 2023

В статье описан малогабаритный цифровой спектрометр-­дозиметр нейтронов и гамма-­квантов SDMF 1608SN нового поколения, который позволяет измерять энергетическое распределения плотности потока нейтронов и гамма-­квантов и рассчитывать любой дозиметрический функционал. Приведены примеры измерения спектров радионуклидных гамма- и нейтронных источников, ускорителей, генераторов, реакторов.
ОБОСНОВАНИЕ ПРИМЕНЕНИЯ ПОМЕХОПОДАВЛЯЮЩЕЙ СХЕМЫ БЕСКОНТАКТНОГО ДАТЧИКА ДЛЯ ИЗМЕРЕНИЯ ДЕФЕКТОВ ГЕОМЕТРИИ
Authors: Епифанцев К.
Published: June 2023

Создан прототип бесконтактного емкостного датчика для измерения дефектов формы для импортозамещения контактного щупа австрийского производства. Приведены результаты теоретического обоснования, исследований технических и методических решений по созданию оптических цифровых приборов, которые могут быть использованы для измерения дефектов формы и шероховатости.
Estado de derecho
Authors: Salmorán Villar María de Guadalupe ,   Instituto de Investigaciones Jurídicas, Salazar Ugarte Pedro ,   Instituto de Investigaciones Jurídicas, Cervantes Alcayde Magdalena ,   Instituto de Investigaciones Jurídicas, Franco Martín del Campo María Elisa ,   Instituto de Investigaciones Jurídicas, Estrada Adán Guillermo Enrique ,   Instituto de Investigaciones Jurídicas, Barceló Rojas Daniel Armando ,   Instituto de Investigaciones Jurídicas, Serna de la Garza José María ,   Instituto de Investigaciones Jurídicas, Rosas Fregoso Roxana ,   Instituto de Investigaciones Jurídicas, Freidenberg Andrés Flavia Daniela ,   Instituto de Investigaciones Jurídicas, Garza Onofre Juan Jesús ,   Instituto de Investigaciones Jurídicas, Martín Reyes Javier ,   Instituto de Investigaciones Jurídicas, Vázquez Valencia Luis Daniel ,   Instituto de Investigaciones Jurídicas, Serrano García Sandra Liliana ,   Instituto de Investigaciones Jurídicas
Published: June 2023

La pandemia puso a prueba el funcionamiento de las democracias constitucionales en diversas partes del mundo. El objetivo de este volumen es contribuir a la comprensión de las repercusiones de la emergencia sanitaria por COVID-19 en el Estado de derecho mexicano. Las reflexiones aquí fomentadas subrayan la importancia de la aplicación del derecho convencional por parte del Estado en la gestión la pandemia, junto a la necesidad de que existan contrapesos y controles constitucionales respecto de las medidas impulsadas por el Gobierno para afrontar la emergencia. Proponen un diagnóstico sobre la capacidad de respuesta del sistema federal mexicano para contener la propagación del virus y proteger a la población más vulnerable. Destacan los esfuerzos institucionales a fin de garantizar la participación política ciudadana y la renovación pacífica, libre y ordenada de los órganos de representación popular en contextos extraordinarios. Finalmente, centran la atención en la creciente militarización del país que, si bien tiene un origen anterior, durante la pandemia se ha profundizado, ampliado y diversificado, lo que pone en riesgo los derechos humanos y la naturaleza democrática del Estado.
Experimental and Simulation Analysis to Predict the Optimum Biodiesel Yield from Two Different Feedstock Using Heterogenous Base Catalyst
Authors: Srinithi J.
Published: June 2023

Abstract: Biodiesel can be easily used an alternative fuel. Using the Soxhlet apparatus, the oil waas extracted, and centrifuged to separate the oil. The physical characteristics of oil was determined. A number of >3 indicates an acid, while a value < 3 indicates a base. If the FFA content is >0.5, the substance is an acid, and if it’s less than 0.5, a base. Suitable solvent based on its physicochemical characteristics was selected. In this study two types of seeds were used. A mixed heterogeneous base catalyst containing CaO prepared from waste egg shells andcockle shells. The egg shells and cockle shells were dried in microwave oven for 24 hours at 120◦C and placed in Muffle furnace at 900 ◦C and mixed in 1:1 ratio. SEM, EDAX and FTIR were used to characterize the catalyst. The two feedstock used in this study was Solanum Torvum and Murraya Koenigii. Double Step Esterification was preferred. The oil was treatedwith the strong acid H2SO4 . Then oil along with methanol was treated with both acid and basecatalyst separately to give Fatty Acid Methyl Ester. Finally optimum condition was found for maximum yield of FAME, was obtained using RSM.
A Study of Hypervisor Based Virtualization and Related Major Security Issues in Cloud Computing Architecture
Authors: Kumari Neha
Published: June 2023

Abstract: With the use of cloud computing, a comprehensive web platform made up of many different services may be created and used as needed. Through the internet, cloud computing offers its services in an affordable, dependable, and productive manner. By offering services on a rental basis, cloud computing lowers the expenditure required to buy gear, software, and software licenses. It offers backups to maintain multiple copies of the data and lowers the cost of licensing. With the use of cloud computing, a comprehensive web platform made up of many different services may be created and used as needed. One of today's most fascinating technologies is cloud computing, which is scalable, versatile, and can lower the cost and complexity of applications. These advantages turned cloud computing from a far-fetched notion into one of the most rapidly expanding fields of technology today. Actually, virtualization technology is based on an older technique called virtualization, which contains security flaws that need to be fixed before they influence cloud computing. Additionally, limited security features of virtualization technology are needed to protect a wide-area system like the cloud. Therefore, modifications to the conventional virtualization design are needed to create an effective security solution. In order to safeguard the cloud environment, this article suggests novel security architecture in a virtualization technology based on hypervisors.
A Review on Ayurvedic Bitter Herb - Kiratatikta (Swertia chirayita (Roxb.) H. Karst.)- A Plant of Immense Medicinal Value
Authors: Karigar Dr. Shivananda B. , M Dr. Praveen Kumar K
Published: June 2023

Abstract: Kiratatikta (Swertia chirayita (Roxb.) H. Karst.) is a herb with diverse medicinal properties. Name of the plant itself signifies that it is more of bitter taste and this bitterness is due to presence of different active principles like Amarogentin, Swertiamarin and Mangiferin etc. By these active principles it has shown pharmacological activities like Anticancer, and CNS depressant Antiviral activity. Kiratatikta is popularly known for its traditional uses in Jwara, Raktapitta, pidaka and many more. As this herb is now endangered species, another herb called Kalamegha (Androghaphis paniculata) which is having similar properties like Kiratatiktha is being used as substitute. Some authors mention it as adulteran
Mampukah Kebijakan Deviden Sebagai Variabel Intervening?
Authors: Maryanti Eny , Rahayu Ruci Arizanda , Saniyah Kholidiyah
Published: June 2023

This study aims to examine the effect of Profitability, Leverage, and Ownership Structure on Firm Value with Dividend Policy as Intervening Variables. This research method uses a quantitative research method with secondary data sources in the form of financial reports and annual reports of Food and Beverage Companies listed on the IDX for 2017-2020. Sample selection was carried out using the purposive sampling method and 13 sample companies that met the criteria. The data analysis technique in this study used Eviews 12. The research results show that (1) Profitability has an effect on Dividend Policy (2) Leverage has no effect on Dividend Policy (3) Ownership Structure has no effect on Dividend Policy (4) Profitability has an effect on Firm Value (5) Leverage has no effect on Firm Value ( 6) Dividend Policy has an effect on Firm Value (7) Ownership Structure has no effect on Firm Value (8) Dividend Policy is able to mediate the influence of Profitability on Firm Value (9) Dividend Policy is not able to mediate the influence of Leverage on Firm Value (10) Dividend Policy has no effect mediate the effect of Ownership Structure on Firm Value. Dividend policy can increase or decrease the value of the company when profitability is high or not. Dividend policy cannot increase or decrease the value of the company when leverage and ownership structure are high or not. This empirical study contributes to practice in companies in making policies and becomes a reference for investors in making investment decisions.
Peran Moderasi Manajemen Risiko Perusahaan Terhadap Hubungan Antara Aktivitas Pendanaan Eksternal Dengan Manajemen Laba
Authors: Fajar Rianto Bayu , Faisal Faisal
Published: June 2023

This study examines the relationship between a company's external financing activity and earnings management and enterprise risk management as moderation variable. The sample of the study was 271 companies listed in the Bloomberg database in 2018. The results of this study show that: First, external financing activities of both debt and equity are positively associated with accrual earnings management and real activity earnings management. Second, enterprise risk management has a significant influence on the relationship between external funding activities and earnings management. The results of this study make a significant contribution to stakeholders to strength managers to augment the company's risk management functions in an effort to prevent earnings management practices.
Budaya Akuntansi Indonesia: Praktik Akuntansi Level Keluarga, Masyarakat, dan Bisnis
Authors: Budianto Risky , Latifah Sri Wahjuni , Suhardianto Novrys , Iswati Sri
Published: June 2023

This study describes the accounting culture with the existence of financial cycles among Indonesian people. This research fosters the role of the philosophy of science to see accounting culture in community activities in general from its multi-paradigm perspective. There are various accounting cultures that are spread giving birth to a variety of accounting treatments that are applied in each culture. We make a qualitative systematic review as the basis for the method in this study. The results of the study show that the variety of accounting culture in Indonesia can be classified into three levels, namely the accounting culture at the family level, community level, and business level. The accounting culture that grows in Indonesia is more accountable in nature so it is not a formal object related to the recognition, measurement, and presentation of accounting information. The material object of Indonesian accounting culture is the customary practice of a society that has a social order. Systematics that are consistent and carried out continuously and passed down from generation to generation make the system a culture.
Use of Trained Convolutional Neural Networks for Analysis of Symptoms Caused by Botrytis fabae Sard
Authors: Álvarez-Sánchez David-E , Arévalo Anderson , Benavides Iván Felipe , Salazar-González Claudia , Betancourth Carlos
Published: June 2023

This study evaluated the use of convolutional neural networks (CNN) in agricultural disease recognition, specifically for Botrytis fabae symptoms. An experimental bean culture was used to capture images of healthy and affected leaflets, which were then used to perform binary classification and severity classification tests using several CNN models. The results showed that CNN models achieved high accuracy in binary classification, but performance decreased in severity classification due to the complexity of the task. InceptionResNet and ResNet101 were the models that performed best in this task. The study also utilized the Grad-CAM algorithm to identify the most significant B. fabae symptoms recognized by the CNNs. Overall, these findings can be used to develop a smart farming tool for crop production support and plant pathology research.
Response of commercial potato genotypes Solanum tuberosum L. to Phytophthora infestans (Mont.) de Bary late blight attack
Authors: Rodriguez David , Uribe Pedro , Benavides Carlos Andres
Published: June 2023

Potato (Solanum tuberosum L.) cultivation is an important agricultural activity in the Andean region. The late blight Phytophthora infestans (Mont.) de Bary, considered one of the limiting diseases in production, represents a threat to food security and causes losses ranging from 30 to 100% of yield. This research evaluated the response to the disease in four commercial materials widely planted in the department of Nariño. The evaluation was carried out under field conditions, in the municipality of Pasto, at AGROSAVIA's Obonuco research center, with natural inoculum, under a randomized complete block design with four replications. The response variables evaluated were incidence, severity, leaf area index and yield in the commercial categories. The ICA Única variety, reported as highly resistant in 2001, presented damage levels close to 75%, with a yield reduction of 49.88%, caused mainly by low yields of first category tubers, indicating a loss of its level of resistance, with damage levels similar to the highly susceptible control Diacol Capiro, which presented 100% of the area with symptoms of the disease and a reduction of 89% in yield. The genotypes Pastusa Suprema with disease tolerance characteristics and Superior showed the best performance with a severity level of 30% in each case and yield reductions of 30.5% and 40.92%, respectively. The results highlight the importance of these genotypes and their role as pillars in the integrated management of the disease through the planting of varieties with favorable behavior against the disease.
Study on Vitamin D, Cortisol and Testosterone Values in Male Skiers by Seasonal Cycles
Authors: BUDAK Cemalettin , UÇAN İzzet , TETİK DÜNDAR Sibel , MERTOĞLU Cuma
Published: June 2023

Objective: Ski may be a branch which has the most important representation power of all winter sports. It has further been characterized by a high popularity and population which is divided into sub-branches among itself. One sometimes encounters different performance and physiological indicators in the athletes depending on seasonal cycles, training levels and living conditions during the year. The object of this study is to study vitamin D, cortisol and testosterone values in male skiers by seasonal cycles. Material and Methods: Fourteen male skiers between 12 and 18 years of age participated in the study. Participants were studied in two groups by their age ranges. The Group 1 included 7 males whose age average was 13.0±0.8 years, height average was 153.2±8.0 cm and body weight average were 45.7±2.7 kg. The Group 2 included 7 males whose age average was 16.8±1.3 years, height average was 166.0±4.0 cm and body weight average were 64.2±6.6 kg. We determined the age, height and body mass data of the participants by standard methods. We performed a Wingate anaerobic test (WAnT) in order to determine the anaerobic power level. We took blood samples from the antecubital vein in a seated position. We performed all tests at an altitude of 2.000 meters once in January, April, June and November each. Results: We found a significant difference in the cortisol, WBC, HCT, PP and MP parameters in the intra-group comparison results in the Group 1. And there was a significant difference in vitamin D, PP, AP and PD parameters in the Group 2. In the inter-group comparison results, we found a significant difference only in the testosterone hormone. Conclusions: We thought that the study results supported the literature to a great extent.
Giant paleoburrows in the Porto Alegre metropolitan area (state of Rio Grande do Sul, Brazil).
Authors: Frank Heinrich Theodor , Sekiguchi de Carvalho Buchmann Francisco , Gonçalves de Lima Leonardo , Caron Felipe , Pereira Lopes Renato , Fornari Milene
Published: June 2023

Tunnels dug by semi-fossorial mammals of the South American Cenzoic megafauna are known as paleoburrows and are generally described from isolated records or very restricted regions. A particularly favorable set of conditions allowed the systematic mapping of paleoburrows over more than a decade in the Porto Alegre metropolitan area (Rio Grande do Sul state, Brazil), covering more than 10,000 km2. Through digital prospecting, media strategies and fieldwork, more than 400 paleoburrows were found in this region, usually in large-scale anthropogenic excavations. The structures may consist of a single one or several tunnels, reaching up to two or three dozen. Burrows can be opened or filled with sediments to variable extent. More than 80% of the tunnels are completely filled with sediment, thus classified as crotovines. Their widths range between 0.5 and 3.0 m and their heights are between 0.5 and 2.0 m. Tunnels with a diameter of 1.4 m, with original estimated lengths of more than 50 m, are frequent. Excavation traces on burrow walls and roofs are common, but fossils have not been found. In very flat areas like floodplains or areas with very uneven relief (mountainous), paleoburrows are rare to absent. The largest amount of tunnels were found in regions of hilly and relatively stable relief, dug in different lithotypes except unconsolidated sediments or unaltered magmatic or metamorphic rocks. It is possible that each hill may have several paleoburrows, isolated or in groups, around its base. Thus, the region can be considered the one with the highest known density of paleoburrows of this type in the world so far.
Assessing the Risk of Venous Thromboembolism in Patients with Hematological Cancers using Three Prediction Models
Authors: EL-Sayed Hanaa Ali , Othman Maha , Azzam Hanan , Bucciol Regan , Ebrahim Mohamed Awad , EL-Agdar Mohammed Ahmed Mohammed Abdallah , Tera Yousra , Sakr Doaa H. , Ghoneim Hayam Rashad , Selim Tarek El-sayed
Published: June 2023

Background: Assessment of individual VTE risk in cancer
patients prior to chemotherapy is important. Risk assessment models
(RAM) are available but have not been validated for hematological
malignancy. We aimed to assess validity of the Vienna Cancer and
Thrombosis Study (CATS) score in prediction of VTE in a variety of
hematological malignancies. Methods: This is a prospective
cohort study conducted on 81 newly diagnosed cancer patients undergoing
chemotherapy. Demographic, clinical and cancer related data were
collected and patients were followed up for 6 months for VTE events.
Khorana score (KS) was calculated. Plasma D-dimer and sP-selectin were
measured then V-CATS score was calculated. We assessed modified V-CATS
by using new cut off levels of d-dimer and sP-selectin based on ROC
curve of the patients’ results. Results: Out of the 81 patients
assessed, 2.7% had advanced cancer with metastasis. The most frequent
cancer was Non-Hodgkin lymphoma (39.5%) and 8 patients (9.8%)
developed VTE events. The calculated probability of VTE occurrence using
KS, V-CATS and modified V-CATS scores at cut off levels ≥3 were 87.5%,
87.5%, 100% respectively. The AUC in ROC curve of modified Vienna CATS
score showed significant difference when compared to that of V-CATS and
KS (P= 0.047 and 0.029, respectively). Conclusion: Our data
shows the usefulness of three VTE risk assessment models in
hematological malignancies. Modified V-CATS score is more specific
compared with V-CATS and KS, while all three scores have similar
sensitivity. Implementation of RAM in hematological cancers can help
improve the use of thromboprophylaxis.
Modeling of Isometric Muscle Properties via Controllable Nonlinear Spring, and Hybrid Model of Proprioceptive Receptors
Authors: Spirito Mario
Published: June 2023

This work presents the macroscopic behavior of skeletal muscles seen
from a system theoretic standpoint. Then, according to the data
available in the literature, we propose a first Evaluation model for the
muscle isometric (constant muscle length) force generation depending on
the muscle length and neuronal excitation frequency. Such a model is
instrumental in providing a more physics-inspired model of such an
isometric force by exploiting a nonlinear spring description with
controllable characteristics, such as stiffness and rest length. To
conclude, we propose a hybrid dynamical filter model to describe the
components of the sensory system. This is in charge of feeding back to
the Central Nervous System the measurements of muscle length and its
rate of change.
Comparative case study of Quality Improvement Support Agencies (QISAs) as a systemic quality strategy: France and Québec
Authors: Dare Labante Outcha , Champagne François , Denis Jean-Louis
Published: June 2023

In a high-quality health and social services system, policymakers
encourage action at all levels of change to ensure the consistency of
quality strategies, especially at the systemic level, in which the other
three levels of change are nested and the whole system is structured.
This study aims to present an analysis of Quality Improvement Support
Agencies (QISAs) as a systemic strategy, which has been successfully
implemented in several jurisdictions (countries and states). A
comparative study of two critical cases in two different jurisdictions
was carried out: Haute autorité de santé (HAS) in France and Institut
national d’excellence en santé et services sociaux (INESSS) in Québec,
Canada. Several sources of iteratively collected data were coded using a
systematized approach. All data were processed and analyzed
confidentially using the software QDA Miner 6.0.2. The results showed
that HAS has a wider range of activities and INESSS has a narrower
range. Their statutes of autonomy differ, with the former QISA more
independent of the public power of its jurisdiction and the latter more
at the service of public power. Though their products differ, these
QISAs each have different effects (proximal, intermediate, and ultimate)
on quality improvement in practice settings. Furthermore, it appears
that they have each faced dilemmas in achieving systemic quality
improvement. This study may inspire other jurisdictions to implement
similar systemic quality improvement strategies or strengthen them if
they have already been implemented.
Unraveling the Interplay Between Demography and Landscape Features in Shaping Connectivity and Diversity: Insights from the Leopard Cat on a Subtropical Island
Authors: Sun Pei-Wei , Hsiao Chen , Pei Kurtis Jai-Chyi , Lin Yu-Hsiu , Chen Mei-Ting , Chiang Po-Jen , Wang Ling , Lu Dau-Jye , Liao Pei-Chun , Ju Yu-Ten
Published: June 2023

Elucidating how demography and contemporary landscape features regulate
functional connectivity and diversity is crucial to implementing
effective conservation strategies, especially in highly fragmented
landscapes. We analyzed the impacts of landscape features and
demographic events on the dispersal and genetic structure of a locally
endangered carnivore, the leopard cat (Prionailurus bengalensis), across
subtropical Taiwan. We genotyped 184 samples from both human-impacted
and natural habitats using 12 nuclear microsatellites and a
mitochondrial marker. Bayesian analyses revealed a recent population
decline within the past 200 years, and a current genetic hotspot appears
to have arisen from interbreeding between previously diverged
populations. Genetic clustering and resistance surface modeling support
the notion that the population structure is influenced by manufactured
linear and natural topographical features. We employed a landscape
optimization procedure using two genetic distances to reveal that
highways and elevation are the most significant barriers affecting
leopard cat connectivity. Niche modeling indicated that low temperature
is a primary factor limiting leopard cat occurrence, potentially
explaining why their resistance to movement is positively correlated
with elevation. Utilizing an ensemble approach, we predict that suitable
leopard cat habitat will shrink northward and towards higher more rugged
altitudes. Our study provides genetic evidence that anthropogenic
landscape features compromise the connectivity and persistence of a
vagile carnivore that is under severe pressure from habitat loss and
human activities. Our findings serve as a model for landscape genetic
studies of island carnivores in subtropical regions, aimed at
understanding how manufactured landscapes affect intra-species diversity
and dispersal.
Resting-state EEG in marathon runners compared to sedentary controls
Authors: Moussiopoulou Joanna , Handrack Mirjam , Pross Benjamin , Pogarell Oliver , Keeser Daniel , Halle Martin , Falkai Peter , Scherr Johannes , Hasan Alkomiet , Roeh Astrid
Published: June 2023

Background: Previous studies have described various neuroplasticity
effects of physical activity (PA). EEG studies have described effects
mostly during or shortly after short bouts of PA. This is the first
study to investigate the capability of EEG to display PA-induced
long-lasting plasticity in runners compared to a sedentary control
group. Methods: Thirty trained runners and thirty age- and sex-matched
sedentary controls (SC) were included as a subpopulation of the ReCaP
(Running effects on Cognition and Plasticity) study. PA was measured
with the International Physical Activity Questionnaire (IPAQ). Resting
state EEG of the runners was recorded in the tapering phase of the
training for the Munich marathon 2017. Power spectrum analyses were
conducted using standardized Low-Resolution Electromagnetic Tomography
(sLORETA) and included the following frequency bands: delta: 1.5-6 Hz,
theta: 6.5-8.0 Hz, alpha1: 8.5-10 Hz, alpha2: 10.5-12.0 Hz, beta1:
12.5-18.0 Hz, beta2: 18.5-21.0 Hz, beta3: 21.5-30.0 Hz and total power
(1.5-30 Hz). Results: PA (IPAQ) and BMI differed significantly between
the groups. The other included demographic parameters were comparable.
Statistical non-parametric mapping showed no significant power
differences in EEG between the groups. Discussion: Heterogeneity in
study protocols, especially in time intervals between PA cessation and
EEG recordings and juxtaposition of acute PA-induced effects on EEG in
previous studies could be possible reasons for the differences in
results. Future studies should record EEG at different time points after
PA cessation and in a broader spectrum of PA intensities and forms to
further explore the capability of EEG in displaying long-term PA-induced
neuroplasticity.
Effects of Prevent-Teach-Reinforce Positive Behavior Supports on Class Participation Behaviors and Class Disruption Behaviors of the Student at Risk for ADHD
Authors: Choi A-Ram , Kim Eun Kyung
Published: June 2023

The purpose of this study was to investigate the effects of prevent-teach-reinforce positive behavior support on class participation behaviors and class disruption behaviors of the elementary school student at risk for ADHD. The subject was a elementary school male student at risk for ADHD. To demonstrate the effect of this study, multiple probe baseline design across settings was conducted. Based on Functional Behavior Assessment for the subject, prevent-teach-reinforce positive behavior support(intervention of antecedents and setting events, alternative behavior instruction, consequences and system change) were developed and implemented in a regular classroom and special education classroom. The results of this study were as follows: First, the prevent-teach-reinforce positive behavior support was effective in increasing the class participation behaviors of the student ar risk for ADHD. Second, the intervention was effective in decreasing the class disruption behaviors of the student ar risk for ADHD. The effects of the intervention were maintained after the completion of the intervention and generalized. These results imply that the prevent-teach-reinforce positive behavior support is helpful to improve class participation behaviors of the elementary school student at risk for ADHD and that early intervention is important for the student at risk for ADHD.
The Experience and Perception of ABA therapists on Intervention of Applied Behavior Analysis
Authors: Lee Jeonghae , Choi Jinhyeok
Published: June 2023

The study investigated the learning experiences and perceptions of ABA therapists on intervention of applied behavior analysis. A survey of 84 ABA therapists intervening applied behavior analysis was conducted on learning experience, perceptions and needs. The results of the study are as follows. First, ABA therapists are learning about applied behavior analysis in a variety of ways. Second, ABA therapists recognized the lack of support for team approach, cooperation and environmental system as barriers to intervention of applied behavior analysis. And ABA therapists recognized the budget problems and lack of service providers as barriers to intervention proposals in applied behavior analysis. Although the attitude toward the applied behavior analysis was positive, it was recognized that it took some time to implement the strategy for applied behavior analysis. Third, ABA therapists expected that applied behavior analysis should be intervened early and that intervention would be effective in various areas. In addition, ABA therapists recognized the need for collaboration in relevant fields for effective intervention in applied behavioral analysis. The learning and support needs for intervention of applied behavior analysis were found to have greater demands for individual competence than the environmental system. The results of the study are meaningful as basic data to stabilize the social foundation for intervention of applied behavior analysis and seek qualitative growth measures.
The Effects of Positive Behavior Supports(PBS) for Students with Intellectual Disabilities: A Meta-Analysis of Single Case Design Studies
Authors: Kim Byungkeon , Park Yujeong , Koh Hye Jung
Published: June 2023

This study aimed to explore (a) the roles of Positive Behavior Supports(PBS) as a evidence based practice and (b) its use in classroom/school settings for students with intellectual disabilities. A random-effects model was applied for 25 studies that meet inclusion/exclusion criteria and Tau-U values were caculated to estimate effect sizes according to each moderator (i.e., school level, type of intervention, number of sessions, disability severity, and gender). Results showed that (a) PBS based interventions showed strong effect sizes for both problematic behaviors and alternative behaviors; (b) the strongest effect size was found in elementary level, followed by middle and high school level;(c) both individual intervention and class-wide/school-side approach were effective; and (d) there was no difference in the effect sizes when it comes to gender. Based on the findings, the use of PBS in classroom and school settings for students with intellectual disabilites and future directions for research and practice were discuseed.
Analysis of Research Trends Related to Diagnosis of ASD Through Keyword Network Analysis: Focusing on domestic academic journals published from 2011-2020*
Authors: Choi Jinhyeok , Park Jaekook , Kim Minyoung
Published: June 2023

This study to analyze the research trends of papers related to the diagnosis of autism spectrum disorder by using keyword network analysis. The analysis papers were 42 papers related to the diagnosis of autism disorder published from 2011-2020. As for the analysis data, general research trends, frequency analysis of major keywords, and network analysis were conducted using textome and UCINET. The results of this study are as follows. First, it was confirmed that a total of 42 studies were conducted from 2011 to 2020. Second, most of the papers related to the diagnosis of autism spectrum disorder were found to be academic journals in the field of special education. Third, as a result of examining the frequency of occurrence of major keywords in research related to the diagnosis of autism disorder, it was found in the order of ‘autism spectrum disorder’, ‘early diagnosis’, ‘focus’, ‘early screening’, and ‘infants’. Fourth, the result of TF-IDF weight analysis showed similar results to the order of appearance frequency. Fifth, in the N-gram analysis, the keywords that are highly related to the keyword ‘autism spectrum disorder’ were found to be in the order of ‘early diagnosis’, ‘early screening’, ‘children’, and ‘infants’. In addition, in the analysis of the semantic network, the keyword ‘autism spectrum disorder’ showed ‘early diagnosis’ and the highest degree of center of connection. Sixth, in the CONCOR analysis, the main clusters such as characteristics and support system for ‘autism spectrum disorder’, ‘diagnosis tool development’, and ‘early diagnosis’ were identified. This study analyzed the trends of research related to the diagnosis of autistic disorder, and discussed and suggested future research directions.
The Awareness and the Requirements of Daycare Center Workers for the People with Disability towards Applied Behavior Analysis
Authors: Bang Soo Jin , Lee Sung Bong
Published: June 2023

The purpose of this study is to know the changed awareness since the social workers who directly provide services to have participated in the intervention with applied behavior analysis and about the requirements to be supported for adults with developmental disabilities with applied behavior analysis in the field. Semi-structured in-depth interviews were conducted with 6 workers in daycare centers located in Seoul and Gyeonggi-do. The results according to the research as follows: First, workers took a very positive direction that it needs to be applied for them because applied behavior analysis intervention for adults with intellectual disabilities and autism spectrum disorders got the distinct result, Second, professionals and financial supports were required for the field application. The results of this study demonstrated that applied behavior analysis intervention is the effective method for adults with developmental disabilities and proposed the demands to apply it concretely at daycare centers.
The Effects of Self-Monitoring Checklist containing Self-Management Intervention on Work Productivity for Student with Intellectual Disability who placed in special schools’ majoring courses
Authors: Ha Taewoo , Choi Jinhyeok
Published: June 2023

The purpose of this study was to analyze the effects of using self-monitoring checklist containing self-management intervention on work productivity. For this purpose a student with intellectual disability who placed in special schools’ majoring courses was selected as a participant, and the experiment was conducted in a structured classroom setting. For this study, a multiple probe design across settings was used to identify a potential functional relationship between independent and dependent variables. The independent variable of this study was the self-management intervention which was materialized as ‘Self-Monitoring card’ including self-monitoring, self-evaluation, and self-reinforcement. The dependent variable of this study was the student’s work productivity which was measured by the number of products and the ratio of products without error at one period. During the intervention student’s work productivity was improved in all working settings, and the improved work productivity was maintained or more improved after the intervention. The result from this study demonstrated that the self-monitoring checklist has a positive effects on student’s work productivity.
A Study on the Analysis of Behavior Support Policy for Children
with Special Education Needs and disabilities(SEND) in South
Korea
Authors: Park Gye-Shin
Published: June 2023

The purpose of this study is to identify the behavioral support policy for
children with special education needs and disabilities(SEND) in South Korea.
Specifically, the Ministry of Education’s special education operation plan from
2018 to 2021 was analyzed in order to find out the details of the government’s
behavioral support policy and trend. In addition, in order to understand the
details of the local government’s recent behavior support policy for children
with SEND, 17 cities and provinces’ special education operation plans for 2021
were analyzed through the content analysis method. As a result of the study, the
following two characteristics were found. First, from 2018 to 2021, the
government’s behavioral support policy for children with SEND appeared in three
categories: team-based positive behavior support, human/material resources and
policy operation support, and building capacity of school members for behavior
supports. The sub-elements and contents of each category were progressively
specialized and detailed by year, and the beneficiaries gradually expanded.
Second, the local government’s behavioral support policy for children with SEN
in 2021 was classified into three categories in the same way as the government’s
policy. Sub-elements and contents of local government policies showed common
policies based on government policies, and it was also found that differentiated
policies were established according to the characteristics of local governments.
Based on the research results, future behavior support policy directions for
children with SEND were suggested.