bluuebunny/crossref_metadata_2025 huggingface dataset:
Emerging SARS-CoV-2 Genetic Variations and Mutations in the COVID-19 genomic sequence: A Systematic and Meta-analysis review
Authors: Valadan Reza , Alizadeh-Navaei Reza , Golpour Monireh , Gholami Mehrdad , Zargari Mehryar , Haghshenas Mohammadreza , Mousavi Tahoora
Published: March 2021

Objectives Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). The high mutation rate of RNA viruses causes genetic variation, virus evolution and it is a strategy to escape the immune system. In the present study, all researches and evidence were extracted from the available online national databases. Two researchers randomly evaluated the assessment of the research sensitivity. Finally, after quality assessment and specific inclusion and exclusion criteria, the eligible articles were entered for meta-analysis. The heterogeneity between the results of studies was measured using test statistic (Cochran's Q) and I2 index. The forest plots illustrated the point and pooled estimates with 95% confidence intervals (crossed lines). All statistical analyses were performed using Comprehensive meta-Analysis V.2 software.This meta-analysis included 13 primary studies investigating the SARS-CoV-2 genetic variations and mutations in the COVID-19 genomic sequence. According to the pooled prevalence (95% confidence interval) of mutations, the spike gene variations showed the highest non-synonymous mutation frequency (16.4%, CI: 13.6, 16.6) and the Non-structural protein (NSP) genes possess the highest mutation frequency among total mutations (31.6%, CI: 21, 44.6). Genomic mutation analysis of SARS-CoV-2 strains may provide knowledge about different biological infrequent mutations and their relationships of viral transmission, pathogenicity, infectivity, and fatality rates between SARS-CoV-2 and human cells.
Theta-burst stimulation entrains frequency-specific oscillatory responses
Authors: Solomon Ethan , Sperling Michael , Sharan Ashwini , Wanda Paul , Levy Deborah , Lyalenko Anastasia , Pedisich Isaac , Rizzuto Daniel , Kahana Michael
Published: March 2021

Brain stimulation has emerged as a powerful tool in human neuroscience, becoming integral to next-generation psychiatric and neurologic therapeutics. Theta-burst stimulation (TBS), in which electrical pulses are delivered in rhythmic bouts of 3–8 Hz, seeks to recapitulate neural activity seen endogenously during cognitive tasks. A growing literature suggests that TBS can be used to alter or enhance cognitive processes, but little is known about how these stimulation events influence underlying neural activity. In particular, it is not understood whether TBS evokes persistent theta oscillations, whether these oscillations occur at the stimulated frequency, and whether stimulation events propagate in a manner consistent with underlying functional and structural brain architecture. To answer these questions, we recruited 20 neurosurgical patients with indwelling electrodes and delivered direct cortical TBS at varying locations and frequencies. We find that TBS rapidly evokes theta rhythms in widespread brain regions, preferentially at the stimulation frequency, and that these oscillations persist for hundreds of milliseconds post stimulation offset. Furthermore, the functional connectivity between recording and stimulation sites predicts the strength of theta response, suggesting that underlying brain architecture guides the flow of stimulation through the brain. These results show that TBS can be used to directly and predictably influence the activity of cognitively-relevant brain networks.
Genome Data of Four Pythium insidiosum Strains from the Phylogenetically-Distinct Clades I, II, and III
Authors: Krajaejun Theerapong , Kittichotirat Weerayuth , Patumcharoenpol Preecha , Rujirawat Thidarat , Lohnoo Tassanee , Yingyong Wanta
Published: March 2021

Objectives: We employed the Illumina NGS platform to sequence genomes of 4 different strains of Pythium insidiosum, an oomycete that causes a serious infection, called pythiosis, in humans and animals. These strains were isolated from humans in Thailand (n=3) and the United States (n=1), and phylogenetically classified into clade-I, -II, and -III. Our study augmented the completeness of the P. insidiosum genome database for exploration of the biology, evolution, and pathogenesis of the pathogen. Data description: Each gDNA sample from the P. insidiosum strains ATCC20026 (clade-I), Pi19 (clade-II), MCC18 (clade-II), and SIMI4763 (clade-III) was processed to prepare one paired-end library (180-bp insert) for whole-genome sequencing by Illumina HiSeq2000/HiSeq2500 NGS platform. A range of 28.4-59.4 million raw reads, accounted for 3.0-7.3 Gb, were obtained and assembled into the genome sizes of 47.1 Mb (15,153 contigs; 85% completeness; 19,329 open reading frames [ORFs]) for strain ATCC20026, 35.4 Mb (14,576 contigs; 83% completeness; 13,895 ORFs) for strain Pi19, 34.5 Mb (11,084 contigs; 84% completeness; 13,249 ORFs) for strain MCC18, and 47.1 Mb (15,162 contigs; 85% completeness; 19,340 ORFs) for strain SIMI4763. The genome data can be downloaded from the NCBI/DDBJ databases under the accessions BCFN00000000.1 (ATCC20026), BCFS00000000.1 (Pi19), BCFT00000000.1 (MCC18), and BCFU00000000.1 (SIMI4763).
Determining the Levels of Some Trace Elements and Heavy Metals (Cu, Mn, Mg, Fe, Zn, CO, Pb and CD) in the Cancers of Lip and Oral Cavity
Authors: DEMİR Derya ÇAY
Published: March 2021

Aim: The aim of the study is to determine the relationship of some trace elements and heavy metals with lip and oral cavity cancer. Materials And Methods: Blood counts of 21 individuals with lip and oral cavity cancer were compared with those in the control group consisting of 30 volunteer and healthy subjects. Levels of trace elements and heavy metals in the serum (Zn, Cu, Mg, Pb, Mn, Cd, Co and Fe) were determined using Atomic Absorption Spectrophotometer method at YUU Central Research Laboratory (Spectrometer: Thermo Scientific C103500100, China). Findings: In this study, the descriptive statistics and comparison results for Cu, Mn, Mg, Fe, Zn, Co, Pb, Cd were found to be statistically significant (p <0.05). According to these results, Zn, Fe, Mn, Mg and Cu levels which are necessary trace elements for human body were found to be significantly lower in patients than healthy control groups. Cd, Co and Pb levels which are harmful and toxic to human body were found to be significantly higher in patients than healthy control groups (p <0.05). Results: Based on these findings of this first and new study in the literature, it was concluded that, trace elements and heavy metals (Cu, Mn, Mg, Fe, Zn, Co, Pb and Cd) in the lip and oral cavity may affect the etiopathogenesis of the disease.
Data driven global weather predictions at high resolutions
Authors: Taylor John , Larraonndo Pablo , de Supinski Bronis
Published: March 2021

Society has benefited enormously from the continuous advancement in numerical weather prediction that has occurred over many decades driven by a combination of outstanding scientific, computational and technological breakthroughs. Here we demonstrate that data driven methods are now positioned to contribute to the next wave of major advances in atmospheric science. We show that data driven models can predict important meteorological quantities of interest to society such as global high resolution precipitation fields (0.25 degrees) and can deliver accurate forecasts of the future state of the atmosphere without prior knowledge of the laws of physics and chemistry. We also show how these data driven methods can be scaled to run on super-computers with up to 1024 modern graphics processing units (GPU) and beyond resulting in rapid training of data driven models, thus supporting a cycle of rapid research and innovation. Taken together, these two results illustrate the significant potential of data driven methods to advance atmospheric science and operational weather forecasting.
Dobutamine Stress Cardiac MRI is Safe and Feasible in Pediatric Patients with Anomalous Aortic Origin of a Coronary Artery (AAOCA)
Authors: Doan Tam T , Molossi Silvana , Sachdeva Shagun , Wilkinson James C , Loar Robert W , Weigand Justin D , Schlingmann Tobias R , Reaves-O’Neal Dana L. , Pednekar Amol S , Masand Prakash , Noel Cory V
Published: March 2021

Background: Risk stratification in anomalous aortic origin of a coronary artery (AAOCA) is challenged by the lack of a reliable method to detect myocardial ischemia. We prospectively studied the safety and feasibility of Dobutamine stress-cardiac magnetic resonance (DSCMR), a test with excellent performance in adults, in pediatric patients with AAOCA. Methods: Consecutive DSCMR from 06/2014-12/2019 in patients 20 years old with AAOCA were included. Hemodynamic response and major/minor events were recorded. Image quality and spatial/temporal resolution were evaluated. Rest and stress first-pass perfusion and wall motion abnormalities (WMA) were assessed. Inter-observer agreement was assessed using kappa coefficient.Results: A total of 224 DSCMR were performed in 182 patients with AAOCA at a median age of 14 years (IQR 12, 16) and median weight of 58.0 kg (IQR 43.3, 73.0). Examinations were completed in 221/224 (98.9%), all studies were diagnostic. Heart rate and blood pressure increased significantly from baseline (p<0.001). No patient had major events and 28 (12.5%) had minor events. Inducible hypoperfusion was noted in 31/221 (14%), associated with WMA in 13/31 (42%). Inter-observer agreement for inducible hypoperfusion was very good (K= 0.87). Asymptomatic patients with inducible hypoperfusion are considered high-risk and those with a negative test are of standard risk.Conclusions: DSCMR is feasible in pediatric patients with AAOCA to assess for inducible hypoperfusion and WMA. It can be performed safely with low incidence of major/minor events. Thus, DSCMR is potentially a valuable test for detection of myocardial ischemia and helpful in the management of this patient population.
Left Ventricular Strain and Left Atrial Strain Are Impaired During Hemodialysis in Children
Authors: Doan Tam T , Sriva Poyyapakkam , Liu Asela , Wilkes J. Kevin , Idrovo Alexandra , Akcan-Arikan Ayse , Swartz Sarah , Geer Jessica , Altman Carolyn A. , Ayres Nancy A. , Loar Robert W , Pignatelli Ricardo
Published: March 2021

Background
Cardiac mortality and morbidity remain significant in children on chronic hemodialysis (HD). Multiple markers by speckle tracking echocardiography (STE) are predictive of cardiac events in adults, but data in children are limited; ventricular diastolic strain (Ds) and left atrial strain (LAS) have not been reported. The aim of this study was to investigate intradialytic changes in ventricular and atrial function using STE in children.
Methods
Secondary analysis of a prospective descriptive study of children with structurally normal hearts and HD vintage > 3 months, using echocardiography performed prior to, during, and after HD. STE was analyzed using GE EchoPAC. Left ventricular (LV) global longitudinal strain (GLS), strain rate (Sr), and mechanical dispersion index (MDI) were calculated as the average from 3 apical views; Ds and Sr were obtained from 4-chamber tracing; LAS and Sr were assessed during atrial contraction, reservoir, and conduit. Intradialytic changes in 2D STE markers of ventricular function and LAS and their association with blood volume (BV) removal and blood pressure (BP) change were studied.
Results
A total of 15 children were enrolled at a median age of 12 years (IQR 8, 16) and median HD vintage of 13 months (IQR 9, 25). GLS was impaired during HD (-15.8 ± 2.2% vs -19.9 ± 1.9%, p < 0.001). Post-HD GLS was associated mean BP decrease (coefficient = 0.62, p = 0.01) and not with BV removal (coefficient = 0.49, p = 0.06). LV MDI and systolic Sr did not change. LV Ds was progressively impaired (-8.4% (-9.2, -8.0) vs − 11.9% (-13.4, -10.3), p < 0.001). LAS conduit and reservoir worsened at mid-HD and returned to baseline post-HD. Changes in Ds, DSr, LAS, LASr were not associated with BV removal or BP decrease (p > 0.1).
Conclusions
Intradialytic LV strain and LAS impairment consistent with subclinical systolic and diastolic dysfunction were observed during HD in children. GLS impairment was associated with BP change, but changes in Ds, DSr, LAS, and LASr were not associated with BP change or BV removal. Longitudinal assessment using these novel non-invasive indices may unfold the effect of cumulative subclinical changes on long-term outcomes in children who are on chronic HD.
Russian Emigration's Literary Heritage in China: a Cultural Code
Authors:   Transbaikal State University, Kim Natalya V.
Published: March 2021

The article is devoted to the literary heritage of the Russian emigration in China and the Russian cultural code, which was preserved in the works of emigrants. A brief overview of the scientific literature, which formed the basis of the research methodology, and a description of the centers of Russian emigration in the Middle Kingdom - Harbin and Shanghai, the living conditions of emigrants are given. The relevance of the topic is due to the attention of modern researchers to the insufficiently studied literary heritage of the “eastern branch” of the Russian emigration.The material for the research was the works from the ten-volume “Literature of Russian emigrants in China” published in 2005 in Beijing. In this work, an integrated research approach is used, when various literary methods are combined with general scientific, linguistic, and private ones. The ten-volume collection includes the works of almost a hundred of Russian writers and poets in China, who for various reasons found themselves in emigration in Harbin, Shanghai and other Chinese cities. This work reveals the frequency themes of emigre creativity: Motherland, China-stepmother, historical events, faith in God, separation, longing for the Fatherland, etc. Basically, these are cultural codes, encoded information transmitted to us by our ancestors and allowing us to identify Russian culture: “Motherland”， “Holy Russia”，“Faith”，“God”，“Icon”，“Love”，“Home”， “Family”，“Soul”，“Hope”，“War”，“Separation”，“Foreign”， “Longing for the Homeland”，etc., as well as concepts (code units) that make up the concept sphere of the Russian picture of the world.The peculiar cultural mission of the Russian writers and poets of the “eastern branch” is that their literature is as much a cultural monument of their time as the works of emigrant writers of the “western branch”. Russian emigrants not only preserved their native culture, language, traditions, religion in exile but also increased the cultural heritage of Russia. The literary work of Russian emigrants in China should become a full-fledged part of the great Russian literature. Keywords: Russian emigrant literature, Russia, China, cultural heritage, cultural code, theme
Dialogue with Russian Literature of the 19th and Early 20th Centuries in the Poetry of Shanghai Emigrant Writers of the 1930s-1940s
Authors:   Institute of Philology, Siberian Branch, Russian Academy of Sciences, Novosibirsk State Technical University, Bogoderova Anna A.
Published: March 2021

The study of preserving cultural identity among emigrants is an important area of modern humanitarian science. The purpose of this article is to analyze intertextual relations with Russian literature of the 19th and early 20th centuries in the poetry of Shanghai emigrant writers of the 1930s-1940s. The novelty of the work is in analyzing a wide range of Shanghai poets' lyrics: M. Shcherbakov, O. Skopichenko, K. Pedenko-Zvantsev, N. Peterets, Yu. Kruzenshtern-Peterets, M. Volin, M. Vezey, B.Volkov. The work uses the method of structural genetic analysis. In the considered group of poems, the texts with love theme prevail. They contain references to the poetry by A.Blok, M. Lermontov, N. Gumilyov and A. Akhmatova. The poems about creativity and the tragic fate of a person refer to the lyrics by F. Tyutchev and V.Bryusov. The first variant of the relationship between the original and the new text is stimulus and response. Separate lines act as an impulse for creating a new text. Thematic connections between the source and the recipient can vary. The second variant is a dispute, polemics. Rethinking and reevaluating of other writer's ideas and characters are demanded in the poetry of emigrants. The greatest agreement with a predecessor can be observed in the love lyrics (O. Skopichenko,M. Vezey). The convergence and contrast are emphasized by M. Shcherbakov, N. Peterets and B.Volkov. The discrepancy and contrast is confirmed by M. Volin and Yu. Kruzenshtern-Peterets. The intertextual elements serve as a source of images and become the basis for a creative dialogue. Keywords: Russian poetry in Shanghai, allusion, citation, epigraph, references, Russian literature of the 19th and early 20th centuries
Development Perspective of Used Electrocar Batteries Management System in Ukraine
Authors: Shuptar-Poryvaieva Nataliia
Published: March 2021

Due to the rapid growth in sales of electric vehicles, the issue of handling their used batteries, which contain toxic substances and without proper disposal can cause significant damage to the environment, becomes extremely important. The purpose of this article is to study the potential of Ukrainian used electrocar batteries management system in the context of the circular economy. The article analyses the dynamics of electrocar market development in Ukraine in the period from 2012 to 2019. With the help of an exponential smoothing algorithm using Microsoft Excel table processor the domestic market of electric transport fill forecast for the next years was made. The forecast results were adjusted for the car market recession caused by the economic crisis due to the coronavirus pandemic. In the course of the research, the experience of the world's leading countries on the issues of handling used electric car batteries was studied, in particular, approaches to legislative regulation of the problem and opportunities for reuse of car batteries with used resource were considered. Emphasis was placed on the fact that modern technology development creates conditions for economic, social and environmental benefits that can be achieved through recycling of used batteries. The economic benefits of recycling Ukrainian electric automotive batteries, which have exhausted their resource was calculated. Еxpedient to reorient the existing methods of used electrocar batteries management system on the principles of circular economy can provide not only improvement of ecological situation in Ukraine, but also lead to its economic growth and welfare of the population was proved.
Managing the Energy-Efficient Development of the University:
Restraints and Ways to Overcome Them
Authors: Sotnyk I.M. , Sotnyk M.I. , Olondar A.A. , Pidopryhora N.M. , Maslii M.Yu.
Published: March 2021

Recently, universities all over the world challenge the problem of reducing energy consumption through the introduction of energy efficient technologies. Higher educational institutions, especially in emerging and developing economies, often face significant barriers to achieving this goal. In developing countries, these obstacles are partly due to technical constraints. However, most of them belong to the organizational, economic, financial, social and educational ones, as is the case in emerging economies. This situation brings up to date the issues of identifying barriers to energy saving on university campuses as well as forming a set of organizational, economic and motivational measures for the energy saving potential implementation in higher educational institutions. On the example of Sumy State University (Ukraine), the study proves a crucial role of the initiative team of energy managers, the necessity of recognition and constant support of the university’s energy efficient development by the topmanagement and wide involvement of teachers and students in energy saving activities. Creating a revolving energy efficiency fund at the university may significantly help to overcome the luck of investment and long-term payback of energy efficient and green energy technologies. In addition, both the promotion of the university’s energy saving achievements by establishing effective communication with all stakeholders and the formation of a system of moral and economic incentives for energy saving essentially contribute to the successful development of energy efficiency policy of the educational institution. The experience of Sumy State University as a case study proves that a systematic approach to the organization of energy saving activities in the university campus based on the continuous improvement of management mechanisms allows achieving the goals of energy efficiency, even with many barriers.
Weak topological insulating phases of hard-core-bosons on the honeycomb lattice
Authors: Ghosh Amrita , Grosfeld Eytan
Published: March 2021

We study the phases of hard-core bosons on a two-dimensional periodic honeycomb lattice in the presence of an on-site potential with alternating sign along the different y-layers of the lattice. Using quantum Monte Carlo simulations supported by analytical calculations, we identify a weak topological insulator, characterized by a zero Chern number but non-zero Berry phase, which is manifested at either density 1/4 or 3/4, as determined by the potential pattern. Additionally, a charge-density-wave insulator is observed at 1/2-filling, whereas the phase diagram at intermediate densities is occupied by a superfluid phase. The weak topological insulator is further shown to be robust against any amount of nearest-neighbor repulsion, as well as weak next-nearest-neighbor repulsion. The experimental realization of our model is feasible in an optical lattice setup.
Arsenic removal from water by nanofiltration membrane: potentials and limitations
Authors: Worou Chabi Noël , Chen Zhong-Lin , Bacharou Taofic
Published: March 2021

Arsenic, in addition to being a confirmed carcinogen, is one of the most toxic elements found in nature, and should therefore be removed if the concentration is greater than 10 μg/L. Nanofiltration (NF) membranes have succeeded in arsenate As (V) ions removal from water almost completely. It is reported in this review that, like reverse osmosis (RO) membranes, NF membranes have not yet performed alone arsenite As (III) ion rejection without being associated with another technology. Commercial NF membranes exhibited a rejection between 86 and 99% towards arsenate As (V) while As (V) removal reached 99.8% for synthesized NF membranes. Since commercial NF membranes have shown their limit, scientists have prepared novel NF membranes that demonstrated long-term efficiency, fouling reduction, cost reduction, an increase in separation of multivalent ions, rejection performance, or a high flux achievement, depending on the area of use. For small treatment plants, NF is a more cost-effective method. The review succinctly reported arsenic as a serious global contamination issue and focused on novel nanofiltration processes for arsenic rejection to safeguard water security. This article also developed a comparative study of nanofiltration and reverse osmosis techniques concerning arsenic removal. Finally, future trends and perspectives have been highlighted with particular emphasis on emerging synthesis techniques of NF membranes without hiding the unpleasant fouling issue that limits its competitiveness.
Geneza i początki kultu Afrodyty
Authors: Zeman-Wiśniewska Katarzyna
Published: March 2021

Afrodyta, grecka bogini miłości i piękna, już wg. autorów starożytnych wywodzić się miała z Cypru, gdzie znajdowała się jej najstarsza znana świątynia w Palaepaphos. Domniemany proces przekształcenia lokalnego bóstwa cypryjskiego w helleńską Afrodytę jest jednak trudny do prześledzenia. Nie podważając jej cypryjskich korzeni, niniejszy artykuł koncentruje się na kwestii genezy jej obecności w greckim panteonie bóstw, dowodząc, iż Afrodyta była od początku bóstwem sensu stricto greckim (greko-cypryjskim), a nie lewantyńskim, którego kult  jedynie wtórnie uległ wpływom kultu Astarte, nim ostatecznie bogini ta stała się częścią panteonu bóstw czczonych przez Greków.
Jeszcze o kasacie klasztoru kanoników regularnych p.w. św. Mikołaja w Kaliszu
Authors: Pobóg-Lenartowicz Anna
Published: March 2021

W 1810 r. doszło do kasaty klasztoru kanoników regularnych p.w. św. Mikołaja w Kaliszu. W Archiwum Diecezjalnym we Włocławku zachował się protokół sekularyzacyjny, przedstawiający stan kościoła, zabudowań klasztornych, wyposażenie kościoła oraz zakrystii. W protokole znajduje się też spis dochodów klasztoru, głownie fundacji mszalnych z miejscowości położonych w pobliskich powiatach oraz z domów znajdujących się w Kaliszu. Z przedstawionego stanu majątkowego wynika, że sytuacja klasztoru była stabilna, co oznacza, że likwidacja konwentu kaliskiego była nieuzasadniona i niezrozumiała.
Kaplica Borzewskich na cmentarzu w Oborach. Przykład budowli grobowej inspirowanej twórczością Friedricha Augusta Stülera
Authors: Wiraszka Marta
Published: March 2021

Przedmiotem analizy jest kaplica grobowa Borzewskich, którą wzniósł w 1863 r. na cmentarzu w Oborach (woj. kujawsko-pomorskie, pow. golubsko-dobrzyński, gm. Zbójno) ówczesny dziedzic Ugoszcza, Zdzisław Borzewski. Architektura budowli, której projektant jest nieznany, wykazuje związki ze współczesnymi realizacjami czołowych berlińskich architektów połowy XIX w. Jej fasada stanowi powtórzenie kruchty kościoła luterańskiego św. Jana Chrzciciela w berlińskiej dzielnicy Moabit (F.A. Stüler, 1851-1857), a obramienia okien w elewacjach bocznych są łudząco podobne do oprawy architektonicznej głównego wejścia do budynku przy Victoriastraße 6 w Berlinie (G.F. Hitzig, 1855-1859).
Prymas Stefan Wyszyński w okresie przełomu 1956-1957
Authors: Łatka Rafał
Published: March 2021

Wydarzenia, jakie miały miejsce w Polsce w październiku 1956 r., przyniosły szereg istotnych zmian w systemie politycznym PRL. Kardynał Wyszyński w ich wyniku powrócił do sprawowania swoich funkcji kościelnych. Stało się to na warunkach prymasa, który wymusił na władzach spełnienie swoich postulatów. W czasie kolejnych miesięcy przełomu politycznego 1956-1957 kard. Wyszyński wykazał się wielkim zmysłem analizy rzeczywistości społecznej oraz wyczuciem realiów, w jakich przyszło mu działać. Uporządkował sytuację wewnętrzną Kościoła i zapewnił mu możliwość autonomicznego działania, nakreślił priorytety na kolejne lata oraz nie dał się nabrać na fałszywe deklaracje władz.
Cele kształcenia w poznańskich szkołach średnich okresu staropolskiego do 1773 r.
Authors: Nowicki Michał
Published: March 2021

Poznań przed 1773 r. posiadał dwie szkoły średnie – Akademię Lubrańskiego oraz kolegium jezuickie. Obie prestiżowe i sławne w ówczesnej Rzeczypospolitej. Czy istniały jakieś elementy ich programu wychowania, które w znaczącym stopniu je różnicowały? Artykuł próbuje udzielić odpowiedzi na to pytanie poprzez analizę celów wychowawczych realizowanych w obu placówkach w omawianym czasie na podstawie tekstów o charakterze normatywnym, zeszytów uczniowskich, skryptów wykładów, publikacji twórczości uczniowskiej, programów teatralnych. Zwłaszcza ta druga kategoria źródeł jest ważna, gdyż pokazuje w sposób pewny, czego faktycznie uczono w tych szkołach, na jakie wartości zwracano szczególną uwagę.
Svenja Ahlhaus: Die Grenzen des Demos
Authors: Rasem Fabian
Published: March 2021

Rezension von Svenja Ahlhaus: Die Grenzen des Demos. Mitgliedschaftspolitik aus postsouveräner Perspektive. Frankfurt am Main: Campus 2020.
Christoph Möllers: Freiheitsgrade
Authors: Heller Jonas
Published: March 2021

Rezension von Christoph Möllers: Freiheitsgrade. Elemente einer liberalen politischen Mechanik. Berlin: Suhrkamp 2020.
The Causality Inference of Public Interest in Restaurants and Bars on Daily COVID-19 Cases in the United States: Google Trends Analysis
Authors: Asgari Mehrabadi Milad , Dutt Nikil , Rahmani Amir M
Published: March 2021

Background

The COVID-19 pandemic has affected virtually every region in the world. At the time of this study, the number of daily new cases in the United States was greater than that in any other country, and the trend was increasing in most states. Google Trends provides data regarding public interest in various topics during different periods. Analyzing these trends using data mining methods may provide useful insights and observations regarding the COVID-19 outbreak.

Objective

The objective of this study is to consider the predictive ability of different search terms not directly related to COVID-19 with regard to the increase of daily cases in the United States. In particular, we are concerned with searches related to dine-in restaurants and bars. Data were obtained from the Google Trends application programming interface and the COVID-19 Tracking Project.

Methods

To test the causation of one time series on another, we used the Granger causality test. We considered the causation of two different search query trends related to dine-in restaurants and bars on daily positive cases in the US states and territories with the 10 highest and 10 lowest numbers of daily new cases of COVID-19. In addition, we used Pearson correlations to measure the linear relationships between different trends.

Results

Our results showed that for states and territories with higher numbers of daily cases, the historical trends in search queries related to bars and restaurants, which mainly occurred after reopening, significantly affected the number of daily new cases on average. California, for example, showed the most searches for restaurants on June 7, 2020; this affected the number of new cases within two weeks after the peak, with a P value of .004 for the Granger causality test.

Conclusions

Although a limited number of search queries were considered, Google search trends for restaurants and bars showed a significant effect on daily new cases in US states and territories with higher numbers of daily new cases. We showed that these influential search trends can be used to provide additional information for prediction tasks regarding new cases in each region. These predictions can help health care leaders manage and control the impact of the COVID-19 outbreak on society and prepare for its outcomes.
The Smartphone App haMSter for Tracking Patient-Reported Outcomes in People With Multiple Sclerosis: Protocol for a Pilot Study
Authors: Altmann Patrick , Hinterberger Werner , Leutmezer Fritz , Ponleitner Markus , Monschein Tobias , Zrzavy Tobias , Zulehner Gudrun , Kornek Barbara , Lanzenberger Rupert , Berek Klaus , Rommer Paulus Stefan , Berger Thomas , Bsteh Gabriel
Published: March 2021

Background

Treatment and monitoring decisions in people with multiple sclerosis (MS) are based commonly on clinician-reported outcomes. These reflect physical and radiological disease activity and are the most relevant endpoints in clinical trials. Over the past few years, the number of studies evaluating so-called patient-reported outcomes (PROs) has been increasing. PROs are reports from patients concerning their own health perception. They are typically obtained by means of questionnaires and aim to quantify symptoms such as fatigue, depression, and sexual dysfunction. The emergence of PROs has made a tremendous contribution to understanding the individual impact of disease in people with MS and their health-related quality of life. However, the assessment of PROs consumes resources, including time and personnel. Thus, useful ways to conveniently introduce PROs into clinical practice are needed.

Objective

We aim to provide a rationale and pilot study protocol for a mobile health (mHealth) solution named “haMSter” that allows for remote monitoring of PROs in people with MS.

Methods

The core function of haMSter is to provide three scientifically validated PRO questionnaires relevant to MS for patients to fill out at home once a month. Thereby, longitudinal and remote documentation of PROs is enabled. A scoring algorithm graphically plots PRO scores over time and makes them available at the next visit.

Results

The pilot study is currently ongoing and will evaluate adherence to this mHealth solution in 50 patients over a period of 6 months. Results from the haMSter pilot study are expected in 2021.

Conclusions

haMSter is a novel mHealth-based solution for modern PRO research, which may constitute the first step in achieving the ability to integrate PROs in clinical practice. This allows for a more problem-oriented approach in monitoring visits, which addresses patient needs and ultimately saves time.

Trial Registration

ClinicalTrials.gov NCT04555863; https://clinicaltrials.gov/ct2/show/NCT04555863

International Registered Report Identifier (IRRID)

DERR1-10.2196/25011
Sentiment Analysis of Users’ Reviews on COVID-19 Contact Tracing Apps with a Benchmark Dataset (Preprint)
Authors: Ahmad Kashif , Alam Firoj , Qadir Junaid , Qolomony Basheer , Khan Imran , Khan Talhat , Suleman Muhammad , Said Naina , Hassan Zohaib , Gul Asma , Al-Fuqaha Ala
Published: March 2021

BACKGROUND

Contact tracing has been globally adopted in the fight to control the infection rate of COVID-19. Thanks to digital technologies, such as smartphones and wearable devices, contacts of COVID-19 patients can be easily traced and informed about their potential exposure to the virus. To this aim, several interesting mobile applications have been developed. However, there are ever-growing concerns over the working mechanism and performance of these applications. The literature already provides some interesting exploratory studies on the community’s response to the applications by analyzing information from different sources, such as news and users’ reviews of the applications. However, to the best of our knowledge, there is no existing solution that automatically analyzes users’ reviews and extracts the evoked sentiments.

OBJECTIVE

In this paper, we analyze how AI models can help in automatically extract and classify the polarity of users’ sentiments and propose a sentiment analysis framework to automatically analyze users’ reviews on COVID-19 contact tracing mobile applications.

METHODS

we propose a pipeline starting from manual annotation via a crowd-sourcing study and concluding on the development and training of AI models for automatic sentiment analysis of users’ reviews. In detail, we collected and annotated a large-scale dataset of Android and iOS mobile application users’ reviews for COVID-19 contact tracing. After manually analyzing and annotating users’ reviews, we employed both classical (i.e., Naïve Bayes, SVM, Random Forest) and deep learning (i.e., fastText, and different transformers) methods for classification experiments. This resulted in eight different classification models.

RESULTS

We employed eight different methods on three different tasks achieving up to an average F1-Scores 94.8% indicating the feasibility of automatic sentiment analysis of users’ reviews on the COVID-19 contact tracing applications. Moreover, the crowd-sourcing activity resulted in a large-scale benchmark dataset composed of 34,534 reviews manually annotated from the contract tracing applications of 46 distinct countries.

CONCLUSIONS

The existing literature mostly relies on the manual/exploratory analysis of users’ reviews on the application, which is a tedious and time-consuming process. Moreover, in the existing studies, generally, data from fewer applications are analyzed. In this work, we showed that automatic sentiment analysis can help in analyzing users’ responses to the application more quickly with significant accuracy. Moreover, we also provided a large-scale benchmark dataset composed of 34,534 reviews from 47 different applications. We believe the presented analysis and the dataset will support future research on the topic.
Analíticas de aprendizaje: una experiencia en Ecuador
Authors: Ortiz Rojas Margarita
Published: March 2021

En este video se presenta el Marco LALA con sus cuatro aspectos fundamentales y la experiencia de haberlo usado en la Escuela Superior Politécnica del Litoral, con ejemplos del beneficio que su uso conlleva. Termina con las lecciones aprendidas de dicha experiencia.
Experiencias en comunicación visual y producción multimedia
Authors: García Trigos Rafael Oliver
Published: March 2021

El presente trabajo presenta el proceso de recopilación de experiencias realizado por la Universidad Autónoma de Nuevo León (UANL) mediante testimonios de profesionales de la comunicación visual y producción multimedia que colaboran en los programas de bachillerato a distancia pertenecientes a la Red de Bachilleratos Universitarios Públicos a Distancia (RED) en México. También se incluyen los videos donde relatan sus experiencias como productores de recursos audiovisuales y explican la importancia de contar en sus bachilleratos con profesionales en estas disciplinas.
Actualización del plan de estudios del Bachillerato General de la Universidad Virtual del Estado de Guanajuato
Authors: Ramírez Juárez Oliverio , Panales Guerrero Carlos Arturo , Ramírez Torres Fátima
Published: March 2021

La actualización del plan de estudios del Bachillerato General de la Universidad Virtual del Estado de Guanajuato (UVEG) integra nuevos elementos sin dejar de lado las características diferenciadoras del plan de estudios anterior. Además de incluir el rediseño del Examen de ubicación (EXU) y del curso de Inducción para el estudio en línea, se fusionan asignaturas con aprendizajes afines. Asimismo, se adicionan nuevas materias para fortalecer el perfil de egreso; se agrega un programa para el desarrollo de habilidades socioemocionales y se flexibiliza el tránsito a través del plan de estudios, al incorporar el concepto de “nivel”, en el que el estudiante podrá elegir qué materia cursa primero.
Migración de una modalidad a otra durante la pandemia
Authors: Cavazos Salazar Rosario Lucero
Published: March 2021

El presente trabajo presenta el proceso realizado por la Universidad Autónoma de Nuevo León (UANL) ante la pandemia del coronavirus SARS-CoV-2, en el cual se realizó una restructuración sobre la estrategia enseñanzaaprendizaje que transforma y crea un movimiento migratorio de la educación presencial a la educación virtual, abriendo así un nuevo paradigma educativo. Se postula como un ejemplo de los retos y soluciones potenciales que enfrentan las instituciones educativas en México y el mundo.  Ante la nueva normalidad, la UANL crea un proyecto denominado Estrategia de educación digital , el cual busca crear, implementar y mejorar el espacio de comunicación y aprendizaje entre maestros y alumnos, utilizando tanto recursos didácticos digitales como herramientas tecnológicas, con el fin de transformar y habilitar los procesos de enseñanza-aprendizaje dentro del ámbito educativo.
La representación de la mujer en la prensa regiomontana: La Tertulia, 1864-1865
Authors: Mijares Cervantes María Teresa
Published: March 2021

En la década de 1860, el semanario La Tertulia fue el primer periódico de Monterrey que incluyó temáticas dedicadas explícitamente a las mujeres. Para explorar la relación de la mujer regiomontana y la prensa periódica, este trabajo aborda un análisis discursivo de los temas dedicados a la mujer en 15 números de La Tertulia (nov. 1864 - mar. 1865). Con objeto de examinar la presencia femenina en el periódico, primero se ofrece una revisión general de los contenidos y su organización. Luego, se analiza la inserción de temas pensados para la mujer, como el teatro, la poesía y el cuento. Las conclusiones apuntan hacia una figura femenina idealizada por el Romanticismo, para la cual aún no se aprecia el reconocimiento de una función social que le permita colaborar activamente en la sociedad, desde el espacio doméstico.
DAMPAK TINGGAL ATAU BEKERJA DI LINGKUNGAN PERTAMBANGAN DAN INDUSTRI TERHADAP KEJADIAN TUMOR GANAS
Authors: Marissa Nelly , Fitria Eka , Nur Abidah , Ichwansyah Fahmi
Published: March 2021

Perkembangan pertambangan dan perindustrian selain meningkatkan ekonomi masyarakat juga memberi dampak terhadap kesehatan, diantaranya adalah meningkatnya kejadian kanker. Tujuan penelitian ini adalah untuk mengetahui kejadian kanker pada pekerja dan penduduk di lingkungan pertambangan dan perindustrian. Penelitian observasional analitik ini menggunakan desain cross sectional. Penelitian ini dilakukan dengan menganalisis data riset penyakit tidak menular tahun 2016. Populasi dalam penelitian ini adalah perempuan usia 25-64 tahun yang tinggal di wilayah perkotaan di 76 kabupaten/kota, 34 provinsi di Indonesia. Total, 4398 peserta direkrut sebagai sampel menggunakan kuota sampling. Data dikumpulkan dengan teknik wawancara menggunakan kuesioner. Chi Square digunakan untuk menganalisis data menggunakan SPSS 23. Hasilnya menunjukkan bahwa tinggal di kawasan industri berhubungan dengan kejadian kanker terhadap perempuan (p = 0,009). Penderita kanker telah tinggal di kawasan industri lebih dari 30 tahun, kebanyakan tinggal di kawasan industri phthalate, jarak tempat tinggal dengan kawasan industri ≤ 5 km, industri bersifat khusus, dan kebanyakan responden yang menderita kanker menggunakan air dari sumur-bor/pompa/gali/PDAM. Tinggal dalam waktu yang lama dan jarak yang dekat dengan dengan kawasan industri meningkatkan resiko terhadap kanker pada perempuan.

 

The development of mining and industry besides improving community economic also has an impact on health, such as cancer. The purpose of this study was to determine the incidence of cancer in workers and residents in the mining and industrial environment. This analytic observational study used a cross sectional design. This research was conducted by analyzing data from non-communicable disease research in 2016. The population in this study were women aged 25-64 years living in urban areas in 76 districts / cities, 34 provinces in Indonesia. In total, 4398 participants were recruited as samples using quota sampling. Data were collected by interview technique using questionnaire. Chi Square was used to analyze data using SPSS 23. The results showed that living in industrial areas was associated with cancer incidence of women (p = 0.009). Cancer patients have lived in industrial area for more than 30 years, mostly living in phthalate industry, distance of residence with industrial area ≤ 5 km, specific industry, and most respondents suffering from cancer use water from wells-drill /pump/PDAM. Staying for long periods of time and close proximity to industrial areas increases the risk of cancer in women.
Representations of robots in science fiction film narratives as signifiers of human identity
Authors: Viidalepp Auli
Published: March 2021

Recent science fiction has brought anthropomorphic robots from an imaginary far-future to contemporary spacetime. Employing semiotic concepts of semiosis, unpredictability and art as a modelling system, this study demonstrates how the artificial characters in four recent series have greater analogy with human behaviour than that of machines. Through Ricoeur’s notion of identity, this research frames the films’ narratives as typical literary and thought experiments with human identity. However, the familiar sociotopes and technoscientific details included in the narratives concerning data, privacy and human–machine interaction blur the boundary between the human and the machine in both fictional and real-world discourse. Additionally, utilising Haynes’ scientist stereotypes, the research puts the robot makers into focus, revealing their secret agendas and hidden agency behind the artificial creatures.
Beyond the Empirical Turn: Elements for an Ontology of Engineering
Authors: Cera Agostino
Published: March 2021

This paper aims to sketch a critical historicisation of the empirical turn in the philosophy of technology. After presenting Achterhuis’s definition of the empirical turn, I show how its final outcome is an ontophobic turn, i.e. a rejection of Heidegger’s legacy. Such a rejection culminates in the Mr Wolfe Syndrome, the metamorphosis of the philosophy of technology into a positive science which, in turn, depends on an engineerisation/problematisation of reality, i.e. the eclipse of the difference between ‘problem’ and ‘question’. My objection is that if Technology as such becomes nothing, then the paradoxical accomplishment of the empirical turn is the self-suppression of the philosophy of technology. As a countermovement, I propose an ontophilic turn, i.e. the establishment of a philosophy of technology in the nominative case whose first step consists in a Heidegger renaissance.
Reservoritis, una complicación del tratamiento quirúrgico de la colitis ulcerativa. Diagnóstico y tratamiento. Revisión
Authors: Otero Regino William , Otero Parra Lina , Veitía Guillermo
Published: March 2021

Del 20 % al 30 % de los pacientes con colitis ulcerativa (CU) son sometidos a cirugía, ya sea por intratabilidad, curso fulminante, aparición de displasia o cáncer de colon. La cirugía de elección es la proctocolectomía con reservorio ileoanal. Sin embargo, el 20 %-50 % de los pacientes presentan reservoritis a 10 años. El diagnóstico se realiza con base en las manifestaciones clínicas, las alteraciones endoscópicas y la histología. Los medicamentos utilizados en el tratamiento de la CU no son tan eficaces en la reservoritis y el tratamiento de primera línea es los antibióticos. Dependiendo de la respuesta inicial y el curso clínico de la entidad, se elegirá el tratamiento posterior. En esta revisión se discuten los aspectos más importantes con respecto a la epidemiología, diagnóstico, patogénesis y tratamiento de la reservoritis.
Gastritis enfisematosa en asociación a un adenocarcinoma gástrico, a propósito de un caso
Authors: Vanegas Duarte Esteban , Duque Montaño Angélica María
Published: March 2021

A través del presente reporte se describe un caso de gastritis enfisematosa, una rara condición clínica consistente en la invasión de la pared gástrica por microorganismos productores de gas. Puede resultar en una situación fatal debido a lo inespecífico de su clínica y a lo tórpido de su evolución. En este caso se describe a un paciente anciano de 77 años, con alta fragilidad, quien cursaba con un cuadro de gastritis enfisematosa que no respondió a manejo médico y requirió gastrectomía de urgencia. Adicionalmente, cursaba con un adenocarcinoma gástrico ulcerado infiltrante, que previamente no había sido diagnosticado, como probable factor condicionante y desencadenante.
Mucosectomía endoscópica para cáncer gástrico temprano: una alternativa vigente
Authors: Ferreira Bohórquez Edgar Julián , Cala Noriega Carlos Hernando , Villa Córdoba Juan David , García Ayala Ernesto
Published: March 2021

La mucosectomía endoscópica ha probado ser una alternativa efectiva para el tratamiento del cáncer gástrico temprano; sin embargo, se requiere de un seguimiento estricto para asegurar una conducta de manejo adecuada en caso de recurrencia. Se presenta el caso de un paciente de 54 años, con hallazgo incidental de un carcinoma gástrico temprano, a quien se le realizó mucosectomía endoscópica, con un reporte final de histopatología compatible con adenocarcinoma gástrico temprano y márgenes de resección negativos, con un seguimiento endoscópico e histopatológico a 2 meses negativos para malignidad.