bluuebunny/crossref_metadata_2025 huggingface dataset:
The Process of Ownership Separation in Co-Owned Companies of the Tel Aviv Municipality and the State of Israel. A Case Study
Authors: Ketko Avi , Bedrule-Grigoruță Maria Viorica
Published: January 2019

Professional literature deals extensively with commitment (management and personal commitment), trust between partners and transparency as critical success factors in collaboration in general and in collaboration among public entities in particular. The State of Israel and the Municipality of Tel Aviv owned seven joint subsidiaries with different holdings in each of the companies. The Israeli government made a decision to sell the State's shares in these companies to the Tel Aviv Municipality. In 2016, a long process, of over eight years of negotiations, between the parties on a commercial basis, came to an end. The purpose of this article is to demonstrate how the implementation of principles of commitment, trust and transparency in practice led to the successful conclusion of the process. The research method was qualitative research, using semi-structured interviews, in the process where involved 12 people.
Ordolieral Roots of Ecological Market Economy
Authors: Dahl Martin
Published: January 2019

Western Germany introduced the model of a Social Market Economy after World War II. This model has become an example of socio-economic reforms for many European countries. In the initial phase of the development of the new socio-economic policy concept, the postulate of "prosperity for all" was especially appealing as it considers economic policy and social policy as a whole. In subsequent years of development, particularly at the end of the twentieth century, the model of a Social Market Economy has become a source of foundation for creating new concepts and ideas that would include more aspects of responsible and sustainable development combined with proper care for resources and the natural environment. In the view of this, the aim of this paper is to attempt to answer the question of to what extent the Social Market Economy model can lay the foundation for sustainable, responsible and ecological development. In order to be able to answer such a research question, the author based his reasoning and analyses on the theory of ordoliberalism and the following research methods: factual analysis, comparative analysis and analysis of selected publications. The main findings of the research are that the concept of Social Market Economy contains numerous elements that can foster the implementation of the sustainable, responsible and ecological development of countries and societies.
Romania Seen through Foreign Eyes: Prince Charles and the Transylvanian/Romanian Connection
Authors: Şerban Andreea
Published: January 2019

It is no secret that, over the past three decades, Romanian migrants have contributed to an ambivalent image of Romania and that cultural stereotypes have heavily influenced the negative portrayal of Romanians in European media, particularly so in the case of British newspapers (cf. Mădroane 2014). Among the people who have fought against such stereotypes is the Prince of Wales, who has endeavoured to promote a thoroughly positive image of Transylvania (and, by extension, of Romania) with its natural beauties, resources and traditions. What this paper aims to do is to explore this aspect as well as its effects in Romanian newspapers over a period of approximately eight years (2011-2018).
On Audiovisual Translation: Dubbing
Authors: Nicolae Cristina
Published: January 2019

The present article focuses on dubbing understood as a creative process of “adapting” the source language script/verbalized message/soundtrack to the target language script/verbalized message/soundtrack, challenging principles such as fidelity versus freedom in translation, bringing once again to our attention the much debated ‘reality’ pinpointed by the Italian adage “traduttore tradittore”, yet not from the point of view of untranslatability, but from that of the need for “transadaptation” in the interlingual transfer required by the audiovisual industry.
The Sadomasochism in Awwad’s Life and Writing: The First World War Trauma
Authors: Wisam Lattee
Published: January 2019

The paper focuses on the Sadomasochism of the Lebanese novelist, poet and diplomat Tawifq Yusuf Awwad, due to the horrible childhood which has shaped his character. When the First World War broke out he was three years old, and when the terrible famine killed two-thirds of the people of Mount Lebanon in 1916 he witnessed these scenes of death, I attempt to investigate how such scenes affected on his life and depicted in his early writings.
A Radiography of English Elements in Romania
Authors: Pungă Loredana
Published: January 2019

This article aims to offer some insight into manifestations of language contact in the particular case of English and Romanian. It focuses on lexical, morpho-syntactic, semantic and discourse-related aspects of the influence of the former in the context of the latter. In particular, after pointing out the areas in which anglicization is especially obvious, attention is paid to: the adaptation of anglicisms so as to fit Romanian syntactic patterns; code switching and its functions; borrowing-triggered semantic change; lexical-semantic calques; and patterns of English written genres imposing new standards for equivalent Romanian genres.
Monitoring of indoor air quality in Macedonian homes during summer season
Authors: Apostoloski Zoran , Vilcekova Silvia , Burdova Eva Kridlová , Meciarova Ludmila
Published: January 2019

Measurements of indoor air quality (IAQ) factors in Macedonian homes were aimed at the determination of indoor air temperature, relative humidity, sound pressure level, particulate matters (PMs) and total volatile organic compounds (TVOC). IAQ monitoring were performed in 25 houses during summer period. Results pointed out that sound pressure level were high in most of the houses with mean values of 66.60 dB (A) - 55.30 dB (A). Limit value of 40 dB (A) was exceeded in 72% of houses. Mean values of indoor air temperature and relative humidity ranged from 21.6°C to 28.6°C and from 35.8% to 60.2%, respectively. Mean concentrations of particulate matter concentrations ranged between 9.75 μg/m3 - 71.73 μg/m3 and 23.63 μg/m3 - 145.10 μg/m3 for PM2.5 and PM10, respectively. Level of PM10 were high in 30% of the monitored houses. 56% of houses achieved higher concentration of PM2.5 than permissible value of 25 μg/m3. Excessive presence of TVOC was recorded in monitored homes with mean values from 260 ppm to 791 ppm. Results show that high exposure by noise, concentrations of TVOC and PMs in indoor air can affect family house users. Therefore, the indoor air quality needs to be investigated and people need to be informed about possible health consequences.
Primary energy and CO2 emissions for a district city and a suburb
Authors: Pitonak Anton , Lopusniak Martin , Bagona Miloslav
Published: January 2019

In countries of the European Union, the proportion of buildings in the overall energy consumption represents 40% and their proportion in CO2 emissions 35%. Taking into account dependence of the European Union on import of energy, this represents large quantity of energy and CO2 emissions, in spite of the fact that there exist effective solutions for reduction of building energy demand. In Directive 20-20-20, the European Union adopted three main commitments of fulfillment criteria by 2020. On the basis of this directive, the Slovak Republic declares support of renovation of apartment dwelling houses. Taking into account the fact that state subsidy can be obtained only once, and energy requirements of the European Union are increasingly stricter, a comprehensive approach to renovation of buildings is inevitable. At the same time, it is inevitable to propose the renovation of buildings taking into account requirements stated for buildings for year 2020. Two areas were compared within the case study taking into account primary energy and the quantity of CO2 emissions. Both areas have the same built-up area, but one of them is a district city and the second is a suburb. From results it is obvious that the quantity of primary energy is lower by 88% in the district city than in the suburb. The quantity of CO2 emissions is lower by 69% in the district city than in the suburb.
Horizontal earth-air heat exchanger for preheating external air in the mechanical ventilation system
Authors: Zhelykh Vasyl , Savchenko Olena , Matusevych Vadym
Published: January 2019

To save traditional energy sources in mechanical ventilation systems, it is advisable to use low-energy ground energy for preheating or cooling the outside air. Heat exchange between ground and outside air occurs in ground heat exchangers. Many factors influence the process of heat transfer between air in the heat exchanger and the ground, in particular geological and climatic parameters of the construction site, parameters of the ventilation air in the projected house, physical and geometric parameters of the heat exchanger tube. Part of the parameters when designing a ventilation system with earth-air heat exchangers couldn’t be changed. The one of the factors, the change which directly affects the process of heat transfer between ground and air, is convective heat transfer coefficient from the internal surface of the heat exchanger tube. In this article the designs of a horizontal earthair heat exchanger with heat pipes was proposed. The use of heat pipes in designs of a horizontal heat exchanger allows intensification of the process of heat exchange by turbulence of air flow inside the heat exchanger. Besides this, additionally heat transfer from the ground to the air is carried out at the expense of heat transfer in the heat pipe itself.
Eindimensionaler phononischer Kristall zur Schallisolierung in Stäben
Authors: Wasmer Paul , Prager Jens
Published: January 2019

Die Untersuchung von Schallausbreitung in periodischen Strukturen ist aktuell von großem Interesse für eine zielgerichtete Beeinflussung von Schallwellen in einem großen Frequenzbereich. Hierbei liegt der Fokus insbesondere auf den phononische Kristalle (PnK’s), einer periodische Anordnung von Streuzentren in einer Matrix. PnK’s können neben anderen Anwendungen, wie der Sensoranwendung oder der Nutzung als effektiver Wellenleiter, als Schallisolator dienen. In dieser Arbeit wird ein neuartiger PnK aus einer periodischen Anordnung von Zylindern untersucht, welcher zur Schallisolation verwendet werden kann. Zunächst wird die Struktur simuliert, dabei wird ein achsensymmetrisches Modell mit einem 3D-Modell verglichen. Im Anschluss wird die simulierte Geometrie gefertigt und vermessen.
The thermopower of NiCr- and PtRh-alloys – a new view
Authors: Bärner Klaus , Morsakov Wladimir , Irrgang Klaus
Published: January 2019

For the interpretation of the Seebeck coefficient

S
(
T
)

S(T)

of transition metal alloys where one or both of the alloy partners develop a spin moment, so far spincluster models in connection with the standard Boltzmann-Fermi theory

S
(
T
)
∼
T

S(T)\sim T

have been adopted. However, this interpretation suffers from some obvious inconsistencies, in particular with NiCr-alloys. In this contribution we try to alleviate these inconsistencies by implementing the recently proposed correlated electron thermopower terms which appear in the framework of Fermi-Boltzmann statistics when it is applied to Stoner-Slater intraatomic exchange (J) split electronic states. For both NiCr- and PtRh-alloys we recover the typical electron correlation term of the thermoelectric power,

S

D

{S_{D}}

, while former inconsistencies can be removed. As NiCr and PtRh-alloys are often used in high temperature sensing because of their stability, this new interpretation of the thermoelectric power may help to develop a better calibration and compositional choice of alloy-based thermocouples.
PENGARUH BUSINESS CENTER DAN LINGKUNGAN KELUARGA TERHADAP MINAT BERWIRAUSAHA MELALUI SELF AWARENESS
Authors: Kurniawati Yunita Dwi , Kusmuriyanto Kusmuriyanto
Published: January 2019

Tujuan penelitian ini ingin mengetahui pengaruh business center, lingkungan keluarga, dan self awareness terhadap minat berwirausaha siswa SMK Negeri 1 Purbalingga.Populasi penelitian adalah seluruh siswa kelas XI SMK Negeri 1 Purbalingga Tahun Ajaran 2017/2018. Penentuan ukuran sampel menggunakan rumus Slovin. Teknik pengambilan sampel menggunakan proportional random sampling. Teknik pengumpulan data menggunakan angket. Analisis data menggunakan analisis regresi berganda dan analisis jalur. Hasil penelitian menunjukkan bahwa business center berpengaruh positif terhadap minat berwirausaha, lingkungan keluarga tidak berpengaruh positif terhadap minat berwirausaha, self awareness berpengaruh positif terhadap minat berwirausaha, business center tidak berpengaruh positif terhadap self awareness, dan lingkungan keluarga berpengaruh positif terhadap minat berwirausaha. Selanjutnya mengenai pengaruh tidak langsung, business center tidak berpengaruh positif terhadap minat berwirausaha melalui self awareness dan lingkungan keluarga berpengaruh positif terhadap minat berwirausaha melalui self awareness. Saran yang diberikan siswa diharapkan semakin meningkatkan partisipasi dan keseriusannya dalam kegiatan yang berkaitan dengan kewirausahaan.

 

Thepurpose of this study wanted to know the influence of business center, family environment, and self awareness ofinterest in entrepreneurship students SMK Negeri 1 Purbalingga.The research population amounted to all students of class XI SMK Negeri 1 Purbalingga Academic Year 2017/2018.Determination of sample size using Slovin formula. Data collection techniques used questionnaires. Data analysis used multiple regression analysisand path analysis.The results of the description analysis found that interest in entrepreneurship in the high category, business center in the category of support, family environment in the category of support, and self awareness in the category high enough. The result of the research shows that business center have positive effect to entrepreneurship interest, family environment has no positive effect to entrepreneurship interest, self awareness have positive effect to entrepreneurship interest, business center has no positive effect to self awareness, and family environment have positive effect to entrepreneurship interest. Furthermore about the indirect influence, business center has no positive effect on entrepreneurship interest through self awareness and family environment have a positive effect on entrepreneurship interest through self awareness.Suggestions givenby students are expected to increase their participation and seriousness in activities related to entrepreneurship.
PERAN STUDENT ENGAGEMENT DALAM MENINGKATKAN PEMAHAMAN KONSEP AKUNTANSI SISWA SMK NEGERI 2 PEKALONGAN
Authors: Khotimah Dian Suci Husnul , Yanto Heri
Published: January 2019

Penelitian ini bertujuan untuk mengetahui peran student engagement dalam meningkatkan pemahaman konsep akuntansi siswa di SMK Negeri 2 Pekalongan. Subyek penelitian ini adalah siswa kelas XI paket keahlian akuntansi yang berjumlah 100 siswa. Metode pengumpulan data menggunakan kuesioner dan dokumentasi. Metode analisis data yang digunakan adalah analisis statistik deskriptif, pearson correlation, canonical correlation, analisis regresi uji parsial dan simultan. Hasil penelitian menunjukkan bahwa faktor student engagement berkorelasi signifikan dengan faktor pemahaman konsep akuntansi. Hasil analisis canonical correlation menunjukkan bahwa kovariat pemahaman konsep berkorelasi signifikan dengan canonical variablesHasil regresi uji parsialmenunjukkan AC berkorelasi dengan seluruh dependent factors kecuali dengan EXPL. ACL berkorelasi dengan seluruh dependent factors kecuali dengan INF. SSI berpengaruh dengan seluruh dependent factors serta EEE dan SLE tidak memiliki pengaruh dengan seluruh dependent factors. Hasil uji simultan menunjukkan bahwa AC, ACL, SSI, EEE dan SLE secara berturut-turut berpengaruh signifikan terhadap dependent factors.Saran yang dapat diberikan adalah sekolah perlu meningkatkan tantangan akademik yang dapat merangsang keaktifan siswa dengan mengembangkan kegiatan ekstrakurikuler serta menciptakan lingkungan belajar yang mendukung siswa untuk dapat mencapai pemahaman konsep akuntansi.

 

This study aims to determine the role of student engagement to improve the understanding of accounting concepts in SMK Negeri 2 Pekalongan. The subject of this study is the students of XI class which has accounting expertise competence 100 students. The method of data collection using documentation and questionnaire. The data analys method used were descriptive statistic, pearson correlations, canonical correlations, partial and simultan test regression analysis. The result of the study showed that the factor of student engagement have a significant correlation with factor of understanding of accounting concept. The result of canonical correlations analysis show that covariate of understanding of accounting concept have a significant correlation with canonical variables.The result of partial test regression show that AC correlates with all dependent factors except EXPL. ACL correlates with all dependent factors except  INF. SSI affects all dependent factors and the other hand EEE and SLE have no influence with all dependent factors. simultan test results show that AC, ACL, SSI, EEE and SLE has significantly influence dependent factors continously. Suggestions from this study, the school need to improve the academic challenge that stimulate student activeness with developing extracurricular activities and create a learning environment that supports students to beable to achieve understanding of accounting concepts.
PENGARUH UANG SAKU, LOCUS OF CONTROL, DAN LINGKUNGAN TEMAN SEBAYA TERHADAP PERILAKU KONSUMTIF
Authors: Hidayah Nailatul , Bowo Prasetyo Ari
Published: January 2019

Perilaku konsumtif merupakan perilaku membeli secara berlebihan dengan mengutamakan kebutuhan sekunder dan tersier daripada kebutuhan primernya yang menyebabkan seseorang menjadi boros. Penelitian ini bertujuan untuk mengetahui ada tidaknya pengaruh uang saku, locus of control, dan lingkungan teman sebaya terhadap perilaku konsumtif mahasiswa Fakuktas Ekonomi. Populasi penelitian ini adalah mahasiswa Fakultas Ekonomi Universitas Negeri Semarang angkatan 2016 dan 2017 dengan sampel penelitian sebanyak 95 mahasiswa. Metode pengumpulan data dalam penelitian ini menggunakan angket. Data variabel dianalisis menggunakan analisis deskriptif, dan regresi linier berganda. Hasil penelitian menunjukkan bahwa uang saku, locus of control, dan lingkungan teman sebaya berpengaruh terhadap perilaku konsumtif. Secara parsial uang saku berpengaruh positif dan signifikan terhadap perilaku konsumtif. Locus of control berpengaruh negatif dan signifikan terhadap perilaku konsumtif. Serta lingkungan teman sebaya berpengaruh positif dan signifikan terhadap perilaku konsumtif. Berdasarkan hasil penelitian di atas dapat diambil kesimpulan bahwa ada pengaruh uang saku, locus of control, dan lingkungan teman sebaya terhadap perilaku konsumtif mahasiswa Fakultas Ekonomi baik secara simultan maupun secara parsial. Saran yang dapat disampaikan dalam penelitian ini yaitu ketika terjadi kenaikan uang saku, sebaiknya mahasiswa dapat meningkatkan locus of control dirinya serta lebih rasional dalam memilih lingkungan teman sebaya agar tidak terjadi peningkatan perilaku konsumtif pada mahasiswa

 

Consumptive behaviour is behavior for excessively buying things by prioritizing secondary and tertiary needs than primary needs which makes someone extravagant. This study aims to determine whether there is any effect of pocket money, locus of control, and peer environment on consumptive behavior of Economics Faculty students. The population was students of Economics Faculty in the year 2016 and 2017 at Universitas Negeri Semarang with 95 sample students. The method of data collection used was questionnaire. The data variables were analyzedby using descriptive analysis and multiple linear regression. The study result shows that pocket money, locus of control, and peer environment simultaneously affect consumptive behavior. Partially, pocket money positively and significantly affects consumptive behavior. Locus of control negatively and significantly affects consumptive behavior. Moreover, peer environment positively and significantly affects consumptive behavior.Based on the results, it is concluded that there is an effect of pocket money, locus of control, and peer environment on the consumptive behaviour of Economics Faculty students at Universitas Negeri Semarang simultaneously or partially. The suggestiongiven in this study is when pocket money increases, students should enhance locus of control and be more rational in selecting peer environment, so students’ consumptive behaviour will not increase.
PENGARUH GAYA BELAJAR, KESIAPAN BELAJAR MELALUI MOTIVASI BELAJAR SEBAGAI VARIABEL INTERVENING TERHADAP KEAKTIFAN BELAJAR
Authors: Riyanti Fira , Rustiana Ade
Published: January 2019

Tujuan penelitian ini yaitu untuk mengetahui pengaruh gaya belajar, kesiapan belajar, dan motivasi belajar terhadap keaktifan belajar secara langsung dan secara tidak langsung yang dimediasi oleh motivasi belajar. Populasi dalam penelitian ini berjumlah 427 siswa dengan sampel sebanyak 206 siswa. Metode pengumpulan data dalam penelitian ini yaitu menggunakan kuesioner dan dokumentasi. Teknik analisis data menggunakan analisis deskriptif persentase, asumsi klasik, regresi berganda, analisis jalur, dan uji sobel dengan bantuan program SPSS For Windows Release 20. Hasil penelitian menunjukkan bahwa gaya belajar berpengaruh positif dan tidak signifikan terhadap keaktifan belajar, kesiapan belajar berpengaruh positif dan signifikan terhadap keaktifan belajar, motivasi belajar berpengaruh positif dan signifikan terhadap keaktifan belajar, gaya belajar berpengaruh positif dan signifikan terhadap motivasi belajar, kesiapan belajar berpengaruh positif dan signifikan terhadap keaktifan belajar. Motivasi belajar sebagai varibael intervening mampu memediasi secara sempurna pengaruh gaya belajar dan kesiapan belajar terhadap keaktifan belajar. Simpulan penelitian ini yaitu ada pengaruh gaya belajar, kesiapan belajar melalui motivasi belajar terhadap keaktifan belajar siswa kelas X SMK Negeri 2 Temanggung Tahun Ajaran 2017/2018

 

This study aimed to know  the effect of learning style, learning readiness, and learning motivation on learning liveliness directly mediated by learning motivation. The population of this study was 427 students with 206 students as the sample. The method of data collection used questionnaires and documentation. The techniques of data analysis used percentage descriptive analysis, classical assumption, multiple regressions, path analysis, and sobel test. The result showed that learning style positively and insignificantly affected learning liveliness. Learning readiness positively and significantly affected learning liveliness. Learning motivation positively and significantly affected learning liveliness. Learning style positively and significantly affected learning motivation. Learning readiness positively and significantly affected learning motivation. Learning motivation as the intervening readiness on learning liveness. The conclusion was there was an effect of learning style, learning readiness through learning motivation on learning liveliness of student grade X SMK Negeri 2 Temanggung Academic Year 2017/2018.
El Estatuto de Arbitraje de Colombia: hacia un servicio de calidad de las exportaciones para Colombia
Authors: Lozada Pimiento Nicolás
Published: January 2019

Desde la década de los noventa, Colombia se ha mostrado relativamente abierta al arbitraje y ha buscado, de esta manera, alternativas a los largos e incómodos procesos judiciales tradicionales. A pesar de haber contado con normas que regulaban el arbitraje de manera extensiva y haber ratificado varias de las convenciones internacionales relativas a este, Colombia no se caracterizaba por ser una sede atractiva para adelantar arbitrajes internacionales. Con la promulgación de la Ley 1563 de 2012, con la que se adoptó parcialmente la Ley Modelo de Arbitraje de la CNUDMI, Colombia empezó a dar pasos en esta dirección. Este artículo evalúa el estado actual y las perspectivas sobre la regulación arbitral colombiana como sede atractiva para arbitrajes internacionales.
Development of a Novel Mule Deer Genomic Assembly and Species-Diagnostic SNP Panel for Assessing Introgression in Mule Deer, White-Tailed Deer, and Their Interspecific Hybrids
Authors: Russell Ty , Cullingham Catherine , Kommadath Arun , Stothard Paul , Herbst Allen , Coltman David
Published: January 2019

Mule deer (Odocoileus hemionus) are endemic to a wide variety of habitats in western North America, many of which are shared in sympatry with their closely related sister-species white-tailed deer (Odocoileus virginianus), whom they hybridize with in wild populations. Although mule deer meet many ideal conditions for a molecular ecological research species, such as high abundance, ecological importance, and broad dispersal and gene flow, conservation genetic studies have been limited by a relative lack of existing genomic resources and inherent difficulties caused by introgression with white-tailed deer. Many molecular tools currently available for the study of cervids were designed using reference assemblies of divergent model species, specifically cattle (Bos taurus). Bovidae and Cervidae diverged approximately 28 million years ago, therefore, we sought to ameliorate the available resources by contributing the first mule deer whole genome sequence draft assembly with an average genome-wide read depth of 25X, using the white-tailed genome assembly (Ovir.te_1.0) as a reference. Comparing the two assemblies, we identified ∼33 million single nucleotide polymorphisms (SNPs) and insertion/deletion variants. We then verified fixed SNP differences between the two species and developed a 40-loci SNP assay capable of identifying pure mule deer, white-tailed deer, and interspecific hybrids. Assignment capacity of the panel, which was tested on simulated datasets, is reliable up to and including the third backcross hybrid generation. Identification of post-F1 hybrids will be necessary for hybrid zone population studies going forward, and the new mule deer assembly will be a valuable resource for genetic and comparative genomics studies.
Genome-Wide Studies of Rho5-Interacting Proteins That Are Involved in Oxidant-Induced Cell Death in Budding Yeast
Authors: Singh Komudi , Lee Mid Eum , Entezari Maryam , Jung Chan-Hun , Kim Yeonsoo , Park Youngmin , Fioretti Jack D , Huh Won-Ki , Park Hay-Oak , Kang Pil Jung
Published: January 2019

Rho GTPases play critical roles in cell proliferation and cell death in many species. As in animal cells, cells of the budding yeast Saccharomyces cerevisiae undergo regulated cell death under various physiological conditions and upon exposure to external stress. The Rho5 GTPase is necessary for oxidant-induced cell death, and cells expressing a constitutively active GTP-locked Rho5 are hypersensitive to oxidants. Yet how Rho5 regulates yeast cell death has been poorly understood. To identify genes that are involved in the Rho5-mediated cell death program, we performed two complementary genome-wide screens: one screen for oxidant-resistant deletion mutants and another screen for Rho5-associated proteins. Functional enrichment and interaction network analysis revealed enrichment for genes in pathways related to metabolism, transport, and plasma membrane organization. In particular, we find that ATG21, which is known to be involved in the CVT (Cytoplasm-to-Vacuole Targeting) pathway and mitophagy, is necessary for cell death induced by oxidants. Cells lacking Atg21 exhibit little cell death upon exposure to oxidants even when the GTP-locked Rho5 is expressed. Moreover, Atg21 interacts with Rho5 preferentially in its GTP-bound state, suggesting that Atg21 is a downstream target of Rho5 in oxidant-induced cell death. Given the high degree of conservation of Rho GTPases and autophagy from yeast to human, this study may provide insight into regulated cell death in eukaryotes in general.
Sex and Mitonuclear Adaptation in Experimental Caenorhabditis elegans Populations
Authors: Wernick Riana I , Christy Stephen F , Howe Dana K , Sullins Jennifer A , Ramirez Joseph F , Sare Maura , Penley McKenna J , Morran Levi T , Denver Dee R , Estes Suzanne
Published: January 2019

To reveal phenotypic and functional genomic patterns of mitonuclear adaptation, a laboratory adaptation study with Caenorhabditis elegans nematodes was conducted in which independently evolving lines were initiated from a low-fitness mitochondrial electron transport chain (ETC) mutant, gas-1. Following 60 generations of evolution in large population sizes with competition for food resources, two distinct classes of lines representing different degrees of adaptive response emerged: a low-fitness class that exhibited minimal or no improvement compared to the gas-1 mutant ancestor, and a high-fitness class containing lines that exhibited partial recovery of wild-type fitness. Many lines that achieved higher reproductive and competitive fitness levels were also noted to evolve high frequencies of males during the experiment, consistent with adaptation in these lines having been facilitated by outcrossing. Whole-genome sequencing and analysis revealed an enrichment of mutations in loci that occur in a gas-1-centric region of the C. elegans interactome and could be classified into a small number of functional genomic categories. A highly nonrandom pattern of mitochondrial DNA mutation was observed within high-fitness gas-1 lines, with parallel fixations of nonsynonymous base substitutions within genes encoding NADH dehydrogenase subunits I and VI. These mitochondrial gene products reside within ETC complex I alongside the nuclear-encoded GAS-1 protein, suggesting that rapid adaptation of select gas-1 recovery lines was driven by fixation of compensatory mitochondrial mutations.
Mielopatija po raktikaulio osteosintezės Kiršnerio viela
Authors: Migauskas Gintaras , Kšanas Ugnius , Jaržemskas Egidijus
Published: January 2019

Gintaras Migauskas, Ugnius Kšanas, Egidijus JaržemskasVilniaus Greitosios Pagalbos Universitetinė ligoninė, Neurochirurgijos skyrius
Įvadas / tikslas
Kiršnerio vielos migracija po raktikaulio osteosintezės – gana dažna komplikacija, tačiau nugaros smegenų kanalo pažeidimas pasitaiko ypač retai. Pateikiamas klinikinis nugaros smegenų pažeidimo Th2-Th3 lygyje atvejis, kuris pasitaikė po raktikaulio osteosintezės Kiršnerio viela.
Klinikinis atvejis
Dėl juosmens skausmų, laipsniškai progresuojančios paraparezės, dubens organų funkcijos sutrikimo 60 metų ligonis tirtas traumatologų ir neurologų. Iš anamnezės duomenų paaiškėjo sąmonės praradimo epizodas. Buvo diagnozuota ir stuburo osteochondrozė, dešinės slankstelinės arterijos okliuzija. Tiriant rentgenu ir kaklo KT nustatyta Kiršnerio vielos migracija į stuburo kanalą. Ligonis buvo operuotas Neurochirurgijos skyriuje, atlikta Th2 laminektomija, pašalinta viela, pervėrusi stuburo kanalą ir nugaros smegenų maišą. Po operacijos neurologiniai simptomai išnyko.
Išvados
Vielos migracija į stuburo kanalą po raktikaulio osteosintezės – labai reta, bet įmanoma komplikacija. Klinikinė eiga gali būti netipiška, dėl to gali kilti diagnostikos sunkumų.
Prasminiai žodžiai: osteosintezė, Kiršnerio viela, migracija, mielopatija.
Myelopathy after clavicular osteosynthesis with Kirschner wire
Gintaras Migauskas, Ugnius Kšanas, Egidijus Jaržemskas
Background / objective
The aim of our report was to describe a spinal cord lesion and chronic myelopathy after clavicular osteosynthesis due to Kirschner wire migration.
Case report
A 60-year-old male was suffering from low back pain, gradually progressing paraparesis, bladder and bowel dysfunction. An episode of short lost of consciousness was documented during the patient’s examination. Vertebral osteochondrosis and right vertebral artery occlusion were diagnosed. Plain films and CT scan demonstrated Kirschner wire migration to the spinal canal. The surgery was performed in the neurosurgical department: Th2 laminectomy was performed and the wire extracted from the transfixed spinal cord. After the surgery and subsequent rehabilitation the former neurological deficit resolved.
Conclusions
Wire migration after clavicular osteosynthesis is a very rare complication. Early diagnosis may be aggravated by an atypical clinical course and multiple masking symptoms.
Keywords: clavicular osteosynthesis, Kirschner wire migration, myelopathy
Ūminis pankreatitas: naujos rekomendacijos naujam laikotarpiui
Authors: Lunevičius Raimundas
Published: January 2019

Raimundas LunevičiusVilniaus universiteto Bendrosios ir kraujagyslių chirurgijos klinikaVilniaus greitosios pagalbos universitetinės ligoninės 2-asis pilvo chirurgijos skyrius,Šiltnamių g. 29, LT-2043El paštas: rlunevichus@yahoo.com
Primenamos 1997 metais parengtos ir 1998 metais publikuotos ūminio pankreatito įvertinimo ir gydymo Jungtinėje Karalystėje (Britų gastroenterologų draugija) ir Tarptautinės pankreatologų draugijos tarybos atstovų (W. Uhl ir kt., 2002) ūminio pankreatito chirurginio gydymo rekomendacijos. Patariama naudotis abiem gerą įrodomąją vertę turinčiomis sistemomis, nes jose pabrėžiami skirtingi, tačiau klinikinėje praktikoje labai svarbūs dalykai. Šios rekomendacijos turi tapti standartu vertinant ūminiu pankreatitu sergančių ligonių gydymo paslaugų kokybę.
Prasminiai žodžiai: ūminis pankreatitas, rekomendacijos, chirurginis gydymas.
Acute pancreatitis: new guidelines for a new period
Raimundas Lunevičius
United Kingdom guidelines for the management of acute pancreatitis, commissioned by the British Society of Gastroenterology (1997–1998) and IAP guidelines (W. Uhl et al., 2002) for the surgical management of acute pancreatitis are reminded. Both guidelines are useful in clinical practice, because different accents are emphasized there. The guidelines should form the basis for audit studies..
Keywords: acute pancreatitis, guidelines, surgical treatment.
Po laivelio pseudoartrozės įvykusio riešo kolapso eiga ir gydymas
Authors: Jankauskas Arūnas
Published: January 2019

Arūnas JankauskasVilniaus universiteto Ortopedijos, traumatologijosir plastinės chirurgijos klinikaVilniaus greitosios pagalbos universitetinė ligoninėŠiltnamių g. 29, LT-2043 VilniusEl paštas: arunas.jankausk@one.lt
Esant nestabiliai laivelio pseudoartrozei, riešo sąnarys neišvengiamai deformuojasi, prasideda artrozė ir sumažėja sąnario aukštis. Tokia riešo sąnario būklė vadinama riešo kolapsu. Degeneraciniai pokyčiai pasireiškia varginamais skausmais, kontraktūra ir plaštakos jėgos susilpnėjimu. Artrozė prasideda ties stipinkaulio yline atauga ir pasiekusi antrą stadiją išplinta stipininiame laivelio sąnaryje. Trečios stadijos artrozė pažeidžia riešo vidurinį sąnarį, tačiau stipininis mėnulio sąnarys lieka nepakitęs. Dėl antros ir trečios stadijos artrozės išplitimo rekonstruoti laivelį netikslinga. Reikia likviduoti artrozės židinius ir stabilizuoti riešo sąnarį taisyklingoje padėtyje. Pašalinamas laivelis ir atkuriamas riešo aukštis. Atliekama riešo vidurinio sąnario artrodezė. Stipininio mėnulio sąnario judesiai išsaugomi.
Prasminiai žodžiai: laivelio pseudoartrozė, riešo kolapsas, riešo vidurinio sąnario artrodezė
Scaphoid nonunion advanced collapse: development and treatment plan
Arūnas Jankauskas
Longstanding and untreatet scaphoid nonunion leads to painful destruction of the wrist with carpal collapse (scaphoid nonunion advanced collapse). The severity of degenerative arthrosis is classified into three stages and can be treated operatively. The reconstruction of the scaphoid or scapholunate ligament in stages II and III is not a reasonable option. With complete excision of the scaphoid and fusion of the midcarpal joint, all arthritic joint surfaces are eliminated and motion is preserved in the radiolunate joint, which is usually spared of degenerative changes.
Keywords: scaphoid nonunion, carpal collapse, midcarpal arthrodesis
Stuburo juosmeninės dalies kanalo stenozė: klinikinė anatomija, diagnostika (I dalis)
Authors: Uvarovas Valentinas , Kvederas Giedrius , Šatkauskas Igoris
Published: January 2019

Valentinas Uvarovas, Giedrius Kvederas, Igoris ŠatkauskasVilniaus universiteto Ortopedijos, traumatologijos ir plastinės chirurgijos klinikaVilniaus greitosios pagalbos universitetinė ligoninėŠiltnamių g. 29, LT-2043 VilniusEl paštas: valiusuvarovas@delfi.lt
Pasaulyje ženkliai auga pagyvenusių žmonių populiacija, kartu daugėja ligų, kuriomis dažniausiai sergama perkopus į antrą gyvenimo pusę. Viena iš tokių ligų yra stuburo kanalo stenozė, t. y. susiaurėjimas. Dažniausia stuburo kanalo stenozės priežastis yra su amžiumi progresuojantys stuburo degeneraciniai pokyčiai. Ne visada arklio uodegos ar nervų šaknelių spaudimas sukelia dirginimo simptomus, tačiau progresuojant patologiniams anatominiams ir fiziologiniams pokyčiams gali išryškėti klinika. Kartais rentgenologiniai duomenys neatspindi klinikos, todėl labai svarbu tiksliai įvertinti ligos simptomus, jų eigą bei rentgenologinius duomenis, kad būtų pasirinkta tinkama gydymo taktika.
Prasminai žodžiai: stuburo kanalo stenozė, neurogeninė klaudikacija, nervinės šaknelės, arklio uodega
Lumbar spinal stenosis: clinical anatomy, diagnostics
Valentinas Uvarovas, Giedrius Kvederas, Igoris Šatkauskas
Lumbar spinal stenosis remains one of the most frequently encountered clinical important degenerative spinal disorders in the ageing population. Spinal stenosis is a narrowing or stricture of the spinal canal. Cauda equina and nerve root compression are noted in many asymptomatic individuals. The spinal degenerative process associated with ageing leads to pathoanatomical and pathophysiological changes with occasional clinical consequences. With progressive degenerative changes and compression, spinal stenosis may become symptomatic, although the severity of the symptoms is not necessarily associated with the magnitude of the compression seen on imaging studies. A thorough understanding of the etiology, pathologic features and a correlation between the symptoms and the precise location of the thecal sac and nerve root are very important in evaluating the imaging studies and planning appropriate treatment.
Keywords: lumbar spinal stenosis, neurogenic claudication, spinal nerve root, cauda equina
Pirmųjų laparoskopinių varikocelektomijų patirtis
Authors: Keina Vytautas , Kryžauskas Vilimantas
Published: January 2019

Vytautas Keina, Vilimantas KryžauskasSveikatos priežiūros tarnybos prie VRM Respublikinės Vilniaus ligoninėsChirurgijos skyrius, Žygimantų g. 8, LT-01102 VilniusEl paštas: keiniokas@takas.lt
Įvadas / tikslas
Sėklinio virželio venų išsiplėtimas – varikocelė būdinga 15% vyrų. Ji yra 40% vyrų nevaisingumo priežastis. Šios ligos gydymo metodai: skleroterapija, atviroji chirurgija (Lopatkino, Ivanisevičiaus, Palomo metodais). Tobulėjant operacinei įrangai, naudojama mikrochirurginė technika ar laparoskopas. Šio darbo tikslas – įvertinti varikocelės gydymo pranašumus, operuojant laparoskopu.
Ligoniai ir metodai
SPT prie VRM Respublikinėje Vilniaus ligoninėje 2003 m. birželio 19 d. buvo atlikta pirmoji, o iki metų pabaigos – dar 13 laparoskopinių varikocelektomijų. Visiems ligoniams buvo kairės pusės II–IIIo varikocelės, 75% jų diagnozuota profilaktinio patikrinimo metu. Operacijos buvo atliekamos Palomo metodu.
Rezultatai
Ligoniai išrašyti į namus praėjus 2,1 dienos, po operacijos vartota vidutiniškai 1,5 dozės analgetikų (ketanovo, dolsino), operacijos trukmė nuo 60 min. sutrumpėjo iki 25 min. Ankstyvųjų pooperacinių komplikacijų nepasireiškė.
Išvados
Laparoskopinės varikocelektomijos pranašumai: maža operacinė pilvo sienos trauma lemia nestiprius skausmus po operacijos, greitą darbingumo grįžimą, puikų kosmetinį rezultatą, taigi ir ekonominį efektą. Įvaldžius operacinę techniką, labai sutrumpėjo operacijos trukmė.
Reikšminiai žodžiai: varikocelė, laparoskopija, varikocelektomija
Experience of first laparoscopic varicocelectomies
Vytautas Keina, Vilimantas Kryžauskas
Background / objective
The enlargement of the veins that drain the testicles (varicocele) occurs in 15% of males. In 40% it is the cause of infertility in males. The methods of its treatment are: scleroterapy, open surgery (of Lopatkin, Ivanisevic, Palom) performed through a section. With the improvement of surgical equipment, microsurgical technique or laparoscopy are used. The aim of this work was to estimate the advantages of laparoscopic varicocelectomy.
Patients and methods
In the Republican Hospital of Ministry of Internal Affairs, on 19 June 2003 was performed the first, and by the end of the year another 13 laparoscopic varicocelectomies were performed. In all patients varicoceles were left side II–IIIo, 75% of them were diagnosed during preventive health check. The operations were performed by the Palom method.
Results
Postoperative bed stay was 2.1 days, after surgery on average 1.5 of a dose of analgesics was used, the duration of the operation was shortened from 60 min to 25 min. No early postoperative complications were observed.
Conclusions
Laparoscopic varicocelectomy diminishes the surgical trauma of the abdomen wall, postoperative pains, ensures a fast restoring of the ability to work, gives a perfect cosmetic result, and consequently an economic effect. With mastering the surgical technique the duration of the operation is shortened significantly.
Keywords: varicocele, laparoscopy, varicocelectomy
Terapeuto požiūris į Kazio Katiliaus darbus
Authors: Kazlauskienė Irena Eugenija
Published: January 2019

Irena Eugenija KazlauskienėVilniaus universiteto ligoninės Santariškių klinikos Centro filialas,Žygimantų g. 3, LT-01102 VilniusEl paštas: vygantas@dameda.lt
Docentas Kazys Katilius buvo vienas iškiliausių chirurgų, pedagogų ir organizatorių sprendžiant sveikatos priežiūros problemas pokario Vilniuje ir Vilniaus srityje. Tam paskyrė visą gyvenimą. Aprašomas docento K. Katiliaus indėlis plėtojant endokrinologiją 1945–1976 metais.
Reikšminiai žodžiai: K. Katilius, Vilniaus "Raudonojo Kryžiaus" ligoninė, chirurgija
Kazys Katilius works in the eyes of an internist
Irena Eugenija Kazlauskienė
A colleague's reminiscences about the famous surgeon professor Kazys Katilius are presented. He devoted all his life to health care organization in postwar Vilnius and its region. The author describes the personal contribution of the surgeon to the development of endocrinology in 1945–1976.
Keywords: K. Katilius, Vilnius Red Cross hospital, surgery
Chirurgija internete
Authors: Morkevičius Matas
Published: January 2019

Matas MorkevičiusVilniaus universiteto Medicinos fakultetas,M. K. Čiurlionio g. 21, LT-03101 VilniusEl paštas: matasmorkevicius@yahoo.com
Straipsnyje apžvelgiami įvairūs chirurgijos nemokamos literatūros šaltiniai internete – knygos, atlasai, žurnalai, pateikiamos nuorodos, kur juos galima rasti.
Surgery online
Matas Morkevičius
Various surgical electronic books, journals and other databases available free of charge are presented in this paper, also providing the links to them.
Perkutaninė endoskopinė gastrostomija
Authors: Grigaliūnas Aurelijus , Šileikienė Nijolė , Stašinskas Algimantas
Published: January 2019

Aurelijus Grigaliūnas, Nijolė Šileikienė, Algimantas StašinskasVilniaus greitosios pagalbos universitetinė ligoninė,Vilniaus universiteto Bendrosios ir plastinės chirurgijos,ortopedijos, traumatologijos klinikosBendrosios chirurgijos centras,Šiltnamių g. 29, LT-04130 VilniusEl. paštas: nijo@delfi.lt
Įvadas / tikslas
Pateikti perkutaninės endoskopinės gastrostomijos techniką. Nurodyti šio minimaliai invazinio chirurginio metodo indikacijas ir kontraindikacijas. Išanalizuoti Vilniaus greitosios pagalbos universitetinėje ligoninėje atliktų perkutaninių endoskopinių gastrostomijų komplikacijas ir mirties priežastis.
Ligoniai ir metodai
Retrospektyviai išnagrinėti atliktų perkutaninių endoskopinių gastrostomijų 34 atvejai. Ligoniams, kuriems buvo rijimo sutrikimų, gastrostomijos atliktos "stumk" ir "trauk" būdais.
Rezultatai
1996–2003 metais Vilniaus greitosios pagalbos universitetinėje ligoninėje atliktos 34 perkutaninės endoskopinės gastrostomijos: 24 vyrams ir 10 moterų. Amžiaus vidurkis – 55,6 metų. Komplikacijų buvo 9 (26,4%) ligoniams; 4 (11,8%) ligoniai mirė; 5 (14,7%) ligoniams, iškritus gastrostominiams zondams, atliktos regastrostomijos.
Išvados
Perkutaninė endoskopinė gastrostomija – minimaliai invazinė chirurginė operacija. Jos atlikimo technika paprasta, lengvai įvaldoma. Tai intervencija, pasižyminti mažu komplikacijų ir mirčių skaičiumi.
Reikšminiai žodžiai: perkutaninė endoskopinė gastrostomija, enterinis maitinimas, minimaliai invazinė chirurgija
Percutaneous endoscopic gastrostomy
Aurelijus Grigaliūnas, Nijolė Šileikienė, Algimantas Stašinskas
Background / objective
To present the formation technique of percutaneous endoscopic gastrostomy; indications and contraindications of this minimally invasive surgical method. To analyze complications and death rate in patients to whom those gastrostomies were performed at Vilnius University Emergency Hospital.
Patients and methods
Thirty-four cases of percutaneous endoscopic gastrostomies due to dysphagia were reviewed retrospectively. Percutaneous endoscopic gastrostomy formations were performed by the "push" or "pull" methods.
Results
Thirty-four percutaneous endoscopic gastrostomies were performed in Vilnius University Emergency Hospital in 1996–2003 for 24 male and 10 female patients, mean age 55.6 years. Complications were observed in 9 (26.4%) cases; four (11.8%) patients died. In 5 (14.7%) cases regastrostomies were performed when the gastrostomic drainage tube fell out.
Conclusions
Percutaneous endoscopic gastrostomy is a minimally invasive surgical intervention. Its technique is simple, easy to master. This intervention shows a relatively low complication and death rate.
Keywords: percutaneous endoscopic gastrostomy, enteral nutrition, minimally invasive surgery