bluuebunny/crossref_metadata_2025 huggingface dataset:
‘Kesho’ Scenario Development for Supporting Water-Energy Food Security under Future Conditions in Zanzibar
Authors: Newman Rebecca J. S. , Enns Charis , Capitani Claudia , Thorn Jessica P. R. , Courtney-Mustaphi Colin J. , Buckton Sam J. , Om Eugyen Suzanne , Fazey Ioan , Haji Tahir A. , Nchimbi Aziza Y. , Kariuki Rebecca W. , Marchant Robert A.
Published: February 2024

Social-ecological interactions mediate water–energy–food security in small developing islands, but community-scale insights are underrepresented in nexus research. These interactions are dynamic in their response to environmental and anthropogenic pressures and need to be understood to inform sustainable land use planning into the future. This study centered on bringing together diverse stakeholders to explore water–energy–food futures using the “Kesho” (meaning “tomorrow” in Kiswahili) scenario tool for two of the largest islands that comprise the Zanzibar Archipelago. The methodology comprised four core stages: (1) exploration of how past drivers of change impacted water–energy–food security; (2) modeling of a Business as Usual Scenario for land cover change; (3) narrative development to describe alternative futures for 2030 based on themes developed at the community scale; and (4) predictions about how narratives would shape land cover and its implications for the nexus. These results were used to model alternate land cover scenarios in TerrSet IDRISI (v. 18.31) and produce visual representations of expected change. Findings demonstrated that deforestation, saltwater incursion, and a reduction in permanent waterbodies were projected by 2030 in a Business as Usual Scenario. Three alternative scenario narratives were developed, these included Adaptation, Ecosystem Management, and Settlement Planning. The results demonstrate that the effectiveness of actions under the scenario options differ between the islands, indicating the importance of understanding the suitability of national policies across considered scales. Synergies across the alternative scenario narratives also emerged, including integrated approaches for managing environmental change, community participation in decision making, effective protection of forests, cultural sensitivity to settlement planning, and poverty alleviation. These synergies could be used to plan strategic action towards effectively strengthening water–energy–food security in Zanzibar.
Osteonal Damage Patterns from Ballistic and Blunt Force Trauma in Human Long Bones
Authors: Sexton Keira , Schwab Nathalie , Galtés Ignasi , Casas Anna , Armentano Nuria , Brillas Pedro , Garrido Xavier , Jordana Xavier
Published: February 2024

Forensic anthropologists play a key role in skeletal trauma analysis and commonly use macroscopic features to distinguish between trauma types. However, this approach can be challenging, particularly in cases of highly comminuted or incompletely recovered fractures. Histological analysis of microscopic fracture characteristics in fractured bones may thus help provide additional information on trauma type and bone fracture biomechanics in general. This study analysed the extent of microcrack damage to osteons in long bones with blunt force trauma (BFT) and gunshot trauma (GST), from both traumatic death cases and post-mortem experimental fractures. We identified four types of osteonal damage (OD). In traumatic death cases, OD affecting the inside of the osteon and compromising the Haversian canal (type 1) was found to be indicative of BFT. Moreover, OD affecting the cement line (type 3) and interstitial lamellae (type 4) was more common in the GST samples. OD affecting the inside of the osteon without compromising the Haversian canal (type 2) was not found to be indicative of either trauma type. In cases of experimental fractures, our study revealed that post-mortem fractures in dry bone samples featured the highest amount of OD, particularly of type 4. This study also found that the experimentally produced GST featured similar OD patterns to GST death cases. These findings support our hypothesis that there are distinct osteonal damage patterns in human long bones with BFT and GST, which are of relevant value for trauma analysis in forensic anthropology.
The Effect of Comb Cell Size on the Development of Apis mellifera Drones
Authors: Zhang Lifu , Shao Linxin , Raza Muhammad Fahad , Han Richou , Li Wenfeng
Published: February 2024

The growth and development of honeybees are influenced by many factors, one of which is the cell size of the brood comb. Larger worker bees can be obtained by being raised in bigger cells. However, whether cell size has the same effect on drone development is still unknown. Here, using 3D-printed foundations, we observed the development of drones kept in comb cells of different sizes from the late larval stage through eclosion. The results showed that drones in larger cell-size combs had heavier body weights, longer body lengths, and larger head widths, thorax widths, and abdomen widths compared to those in smaller cell-size combs. Furthermore, regardless of developmental stages, the drones’ body weights increased linearly with the comb’s cell size. However, the other morphological changes of drones in different developmental stages were out of proportion to the cell-size changes, resulting in smaller cells with a higher fill factor (thorax width/cell width). Our findings confirm that comb cell size affects the development of honeybees; drones become bigger when raised in large cells.
How Much Does SARS-CoV-2 Infection during Pregnancy Affect the Neonatal Brain, Heart, and Kidney? A Parallel between COVID-19, Vaccination, and Normal Pregnancy
Authors: Popescu Daniela Eugenia , Jura Ana Maria Cristina , Știube Dana , Ciulpan Adrian , Stoica Florina , Șipoș Simona Ioana , Cîtu Cosmin , Gorun Florin , Boia Mărioara
Published: February 2024

During the last decades, a growing number of studies have shown that infections during pregnancy have an important impact on both pregnant women and their fetuses. Our goal was to include newborns from pregnancies with SARS-CoV-2 infection and to investigate the extension of neonatal complications using cardiac, abdominal, and cerebral ultrasonography; hearing testing; and indirect ophthalmoscopy. Likewise, neonates whose mothers were vaccinated against COVID-19 during pregnancy and those from pathology-free pregnancies were examined. A total of 458 mother–newborn dyads were included over a period of 10 months and divided into three groups: the COVID-19 group, vaccine group, and control group. Although six cardiac malformations were found in the COVID-19 group, no correlation was made compared to the vaccine and control group (p = 0.07). Grade 1 intraventricular hemorrhage and hypoxic ischemic encephalopathy were the most prevalent among neonates from mothers with SARS-CoV-2 infection (p = 0.002 and p < 0.001, respectively). The kidney anomaly found to be most frequent in this group was grade 1 unilateral hydronephrosis (p < 0.001). COVID-19 disease during the gestational period had no effect on the auditory or visual function. Our findings highlight the importance of implementing proper infection control practices for future mothers, and by continuing to investigate this topic, we can gather valuable insights that will improve neonatal health in this context.
Effect of Divalent Metal Ions on the Ribonuclease Activity of the Toxin Molecule HP0894 from Helicobacter pylori
Authors: Hyun Ja-Shil , Pun Rabin , Park Sung Jean , Lee Bong-Jin
Published: February 2024

Bacteria and archaea respond and adapt to environmental stress conditions by modulating the toxin–antitoxin (TA) system for survival. Within the bacterium Helicobacter pylori, the protein HP0894 is a key player in the HP0894-HP0895 TA system, in which HP0894 serves as a toxin and HP0895 as an antitoxin. HP0894 has intrinsic ribonuclease (RNase) activity that regulates gene expression and translation, significantly influencing bacterial physiology and survival. This activity is influenced by the presence of metal ions such as Mg2+. In this study, we explore the metal-dependent RNase activity of HP0894. Surprisingly, all tested metal ions lead to a reduction in RNase activity, with zinc ions (Zn2+) causing the most significant decrease. The secondary structure of HP0894 remained largely unaffected by Zn2+ binding, whereas structural rigidity was notably increased, as revealed using CD analysis. NMR characterized the Zn2+ binding, implicating numerous His, Asp, and Glu residues in HP0894. In summary, these results suggest that metal ions play a regulatory role in the RNase activity of HP0894, contributing to maintaining the toxin molecule in an inactive state under normal conditions.
Study on Thermal Characteristics of Angular Contact Ball Bearings Considering Roundness Error
Authors: Yu Yongjian , Ma Ruixiang , Xue Yujun , Liu Yonggang
Published: February 2024

To develop an angular contact ball bearing with low power consumption, a heat generation calculation model for angular contact ball bearings has been established based on bearing quasi dynamics, elastohydrodynamic lubrication theory, heat transfer theory, and Kirchhoff’s law of energy conservation, considering the effects of roundness error, bearing preload, centrifugal effect, and thermal expansion. The correctness of the model is verified through experiments. The influence of different operating conditions and roundness errors on the thermal characteristics of angular contact ball bearings is analyzed. The results of the calculation indicate that when the roundness error order is equal to the number of balls n/2 ± 2 (where n = 1, 2, 3, …), the overall heat generation of the bearing is lower than that without considering the roundness error. When the roundness error order is equal to (2n − 1)/4 ± 2 (where n = 1, 2, 3, …), the overall heat generation of the bearing is higher than that without considering the roundness error. At the same rotating speed, the overall heat generation fluctuates as the roundness error order changes, and the trend becomes more pronounced as the rotating speed increases. The maximum overall heat generation is achieved when the roundness error order equals (2n − 1)/4 times (where n = 1, 2, 3, …) the number of balls. When the roundness error order is equal to n/2 times the number of balls (where n = 1, 2, 3, …), the bearing’s overall heat generation is minimal. The variation in the total heat generated by the bearing is directly proportional to the amplitude of the roundness error. With the increase in roundness error harmonic order, the bearing integral heat generation shows a periodic change, and the change period has a mapping relationship with the number of balls.
A Promising Conductive Lubricant for Space Sliding Electrical Contact: NbSe2-Ti Film
Authors: Yang Yang , Wang Guan , Zhou Xingchen , Su Xingkang , Gu Long
Published: February 2024

Vacuum-sliding electrical contacts find extensive application in aerospace components, yet they face limitations related to inadequate lubrication performance. In this study, we analyzed the design of an emerging conductive lubricant material, NbSe2. A series of NbSe2-Ti films with varying doped Ti contents were prepared through magnetron sputtering technology. We investigated the correlation between the sputtering current and composition, microstructure, mechanical properties, and current-carrying tribological properties of the films. The results indicate that under vacuum and current-carrying conditions, the NbSe2-Ti films demonstrate significant advantages over existing electrical-contact lubrication materials. Compared with electroplated gold films, the NbSe2-Ti films reduced the coefficient of friction from 0.25 to 0.015, thereby improving the wear life by more than six times. This result demonstrates that magnetron-sputtered NbSe2 film can be used as a lubricant for space current-carrying sliding contacts.
Evaluation of Wetting Behaviors of Liquid Sodium on Transition Metals: An Experimental and Molecular Dynamics Simulation Study
Authors: Liang Na , Fu Xiaogang , Zhang Jinquan , Ruan Zhangshun , Qin Bo , Ma Tengfei , Long Bin
Published: February 2024

In sodium-cooled fast reactors, the wettability of sodium with materials is closely related to sodium-related operations and the detection accuracy of instruments and meters, so how to achieve the selection of materials with different wettability requirements is a key problem in engineering design. To meet these requirements, the wetting behaviors of liquid sodium with nine transition metals were investigated using scanning electron microscopy (SEM), X-ray diffraction (XRD), and molecular dynamics (MD) simulations. The results show that metals such as zinc and gold, which react with sodium to form intermetallic compounds at the interface, exhibit superior wettability. Followed by the metals that have strong interatomic interactions even though they do not react with sodium or dissolve each other, such as cobalt, nickel and copper, while the wettability of these systems tends to be poor at low temperatures. Systems that do not react with each other or have strong interatomic affinities proved to be the most difficult to wet. Notably, metals with the closest-packed crystal structures of fcc and hcp generally have better wettability than those with a bcc structure. They can be a valuable guide for experimental research and technical control.
Supercapacitors: An Efficient Way for Energy Storage Application
Authors: Czagany Mate , Hompoth Szabolcs , Keshri Anup Kumar , Pandit Niranjan , Galambos Imre , Gacsi Zoltan , Baumli Peter
Published: February 2024

To date, batteries are the most widely used energy storage devices, fulfilling the requirements of different industrial and consumer applications. However, the efficient use of renewable energy sources and the emergence of wearable electronics has created the need for new requirements such as high-speed energy delivery, faster charge–discharge speeds, longer lifetimes, and reusability. This leads to the need for supercapacitors, which can be a good complement to batteries. However, one of their drawbacks is their lower energy storage capability, which has triggered worldwide research efforts to increase their energy density. With the introduction of novel nanostructured materials, hierarchical pore structures, hybrid devices combining these materials, and unconventional electrolytes, significant developments have been reported in the literature. This paper reviews the short history of the evolution of supercapacitors and the fundamental aspects of supercapacitors, positioning them among other energy-storage systems. The main electrochemical measurement methods used to characterize their energy storage features are discussed with a focus on their specific characteristics and limitations. High importance is given to the integral components of the supercapacitor cell, particularly to the electrode materials and the different types of electrolytes that determine the performance of the supercapacitor device (e.g., storage capability, power output, cycling stability). Current directions in the development of electrode materials, including carbonaceous forms, transition metal-based compounds, conducting polymers, and novel materials are discussed. The synergy between the electrode material and the current collector is a key factor, as well as the fine-tuning of the electrode material and electrolyte.
A Universally Composable Linkable Ring Signature Supporting Stealth Addresses
Authors: Wang Xingkai , Zhu Chunping , Liu Zhen
Published: February 2024

The linkable ring signature supporting stealth addresses (SALRS) is a recently proposed cryptographic primitive, which is designed to comprehensively address the soundness and privacy requirements associated with concealing the identities of both the payer and payee in cryptocurrency transactions. However, concerns regarding the scalability of SALRS have been underexplored. This becomes notably pertinent in intricate blockchain systems where multiple cryptographic primitives operate concurrently. To bridge this gap, our work revisited and formalized the ideal functionality of SALRS within the universal composability (UC) model. This encapsulates all correctness, soundness, and privacy considerations. Moreover, we established that the newly proposed UC-security property for SALRS is equivalent to the concurrent satisfaction of signer-unlinkability, signer-non-slanderability, signer-anonymity, and master-public-key-unlinkability. These properties represent the four crucial game-based security aspects of SALRS. This result ensures the ongoing security of previously presented SALRS constructions within the UC framework. It also underscores their adaptability for seamless integration with other UC-secure primitives in complex blockchain systems.
Ensemble Prediction Method Based on Decomposition–Reconstitution–Integration for COVID-19 Outbreak Prediction
Authors: Ke Wenhui , Lu Yimin
Published: February 2024

Due to the non-linear and non-stationary nature of daily new 2019 coronavirus disease (COVID-19) case time series, existing prediction methods struggle to accurately forecast the number of daily new cases. To address this problem, a hybrid prediction framework is proposed in this study, which combines ensemble empirical mode decomposition (EEMD), fuzzy entropy (FE) reconstruction, and a CNN-LSTM-ATT hybrid network model. This new framework, named EEMD-FE-CNN-LSTM-ATT, is applied to predict the number of daily new COVID-19 cases. This study focuses on the daily new case dataset from the United States as the research subject to validate the feasibility of the proposed prediction framework. The results show that EEMD-FE-CNN-LSTM-ATT outperforms other baseline models in all evaluation metrics, demonstrating its efficacy in handling the non-linear and non-stationary epidemic time series. Furthermore, the generalizability of the proposed hybrid framework is validated on datasets from France and Russia. The proposed hybrid framework offers a new approach for predicting the COVID-19 pandemic, providing important technical support for future infectious disease forecasting.
One Anastomosis Gastric Bypass versus Roux-en-Y Gastric Bypass: A Randomized Prospective Trial
Authors: Karagul Servet , Senol Serdar , Karakose Oktay , Uzunoglu Kevser , Kayaalp Cuneyt
Published: February 2024

Background and Objectives: One anastomosis gastric bypass (OAGB) and Roux-en-Y gastric bypass (RYGB) surgeries are effective methods used in bariatric surgery. There are limited randomized studies comparing these procedures over more than 2 years. Here, we aimed to compare the 3-year results of two bariatric procedures. Materials and Methods: Patients included in this randomized prospective study were compared in OAGB and RYGB groups. A total of 55 patients, aged between 18 and 65, were eligible for the study. Thirteen patients who did not accept randomization were excluded. Patients were evaluated at 6, 12, 24, and 36 months postoperatively. Results: Three patients were excluded from the study due to loss of communication during the clinical follow-up and one due to death by amyotrophic lateral sclerosis, which started in the eighth month after surgery. The study was completed with a total of 38 patients (OAGB; n = 20, RYGB; n = 18). Patients in the two groups were similar in terms of age, gender, body mass index (BMI), and obesity-related comorbidities. At the end of 3-year follow-up, BMI in the OAGB and RYGB groups was 28.80 ± 4.53 kg/m2 and 29.17 ± 5.36 kg/m2, respectively (p = 0.822). Percentage total weight loss (TWL%) was similar. No significant differences were found between the groups regarding percentage excess weight loss (EWL%). Remission of comorbidities was similar. De novo refluxes developed in four OAGB patients; there were no occurrences of these in RYGB patients (p = 0.066). Conclusions: Both OAGB and RYGB are effective in the treatment of morbid obesity. The two procedures are similarly successful in terms of obesity-related comorbidities.
Acquired Cardiovascular Diseases in Patients with Pulmonary Hypertension Due to Congenital Heart Disease: A Case Report
Authors: Ereminienė Eglė , Stuoka Mantvydas , Ordienė Rasa , Plisienė Jurgita , Miliauskas Skaidrius , Tamulėnaitė Eglė
Published: February 2024

Background: Advances in the diagnosis and treatment of congenital heart diseases (CHDs) have resulted in improved survival rates for CHD patients. Up to 90% of individuals with mild CHD and 40% with complex CHD now reach the age of 60. Previous studies have indicated an elevated risk of atherosclerotic cardiovascular disease (ASCVD) and associated risk factors, morbidity, and mortality in adults with congenital heart disease (ACHD). However, there were no comprehensive guidelines for the prevention and management of acquired cardiovascular diseases (CVDs) in ACHD populations until recently. Case presentation: A 55-year-old man with Eisenmenger syndrome and comorbidities (arterial hypertension, heart failure, dyslipidemia, hyperuricemia, and a history of pulmonary embolism (PE)) presented with progressive breathlessness. The electrocardiogram (ECG) revealed signs of right ventricle (RV) hypertrophy and overload, while echocardiography showed reduced RV function, RV overload, and severe pulmonary hypertension (PH) signs, and preserved left ventricle (LV) function. After ruling out a new PE episode, acute coronary syndrome (ACS) was diagnosed, and percutaneous intervention was performed within 24–48 h of admission. Conclusions: This case highlights the importance of increased awareness of acquired heart diseases in patients with pulmonary hypertension due to CHD.
The Role of Gut Microbiota and the Potential Effects of Probiotics in Heart Failure
Authors: Petruzziello Carmine , Saviano Angela , Manetti Luca Luigi , Macerola Noemi , Ojetti Veronica
Published: February 2024

Heart failure (HF) remains a significant global health challenge, affecting millions of individuals worldwide and posing a substantial burden on healthcare systems. HF is a syndrome of intricate pathophysiology, involving systemic inflammation, oxidative stress, metabolic perturbations, and maladaptive structural changes in the heart. It is influenced by complex interactions between cardiac function, systemic physiology, and environmental factors. Among these factors, the gut microbiota has emerged as a novel and intriguing player in the landscape of HF pathophysiology. The gut microbiota, beyond its role in digestion and nutrient absorption, impacts immune responses, metabolic processes, and, as suggested by evidence in the literature, the development and progression of HF. There is a bidirectional communication between the gut and the heart, often known as the gut–heart axis, through which gut microbiota-derived metabolites, immune signals, and microbial products exert profound effects on cardiovascular health. This review aims to provide a comprehensive overview of the intricate relationship between the gut microbiota and HF. Additionally, we explore the potential of using probiotics as a therapeutic strategy to modulate the gut microbiota’s composition and attenuate the adverse effects observed in HF. Conventional therapeutic approaches targeting hemodynamic and neurohormonal dysregulation have substantially improved the management of HF, but emerging research is exploring the potential implications of harnessing the gut microbiota for innovative approaches in HF treatment.
Revealing Insights: A Comprehensive Overview of Gastric Outlet Obstruction Management, with Special Emphasis on EUS-Guided Gastroenterostomy
Authors: Ziogas Dimitrios , Vasilakis Thomas , Kapizioni Christina , Koukoulioti Eleni , Tziatzios Georgios , Gkolfakis Paraskevas , Facciorusso Antonio , Papanikolaou Ioannis S.
Published: February 2024

Gastric outlet obstruction (GOO) poses a common and challenging clinical scenario, characterized by mechanical blockage in the pylorus, distal stomach, or duodenum, resulting in symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its diverse etiology encompasses both benign and malignant disorders. The spectrum of current treatment modalities extends from conservative approaches to more invasive interventions, incorporating procedures like surgical gastroenterostomy (SGE), self-expandable metallic stents (SEMSs) placement, and the advanced technique of endoscopic ultrasound-guided gastroenterostomy (EUS-GE). While surgery is favored for longer life expectancy, stents are preferred in malignant gastric outlet stenosis. The novel EUS-GE technique, employing a lumen-apposing self-expandable metal stent (LAMS), combines the immediate efficacy of stents with the enduring benefits of gastroenterostomy. Despite its promising outcomes, EUS-GE is a technically demanding procedure requiring specialized expertise and facilities.
Adipokines, Vitamin D, and Selected Inflammatory Biomarkers among Parkinson’s Disease Patients with and without Dyskinesia: A Preliminary Examination
Authors: Milanowski Jan , Nuszkiewicz Jarosław , Lisewska Beata , Lisewski Paweł , Szewczyk-Golec Karolina
Published: February 2024

Parkinson’s disease (PD), a widely recognized neurodegenerative disorder, is characterized by a spectrum of symptoms including motor fluctuations and dyskinesia. Neuroinflammation and dysregulation of adipokines are increasingly implicated in the progression of PD. This preliminary study investigated the levels of inflammatory biomarkers and adipokines, namely interleukin-6 (IL-6), tumor necrosis factor α (TNF-α), C-reactive protein (CRP), visfatin, progranulin, and 25(OH)-vitamin D in 52 PD patients, divided equally between those with and without dyskinesia and 26 healthy controls. Significant differences in the levels of IL-6, TNF-α, visfatin, and progranulin were noted between the groups. Patients with dyskinesia exhibited notably higher IL-6 levels compared to controls, and TNF-α was significantly elevated in both PD patient groups relative to the control group. Additionally, visfatin levels were higher in PD patients without dyskinesia as opposed to those with dyskinesia, and progranulin levels were elevated in the non-dyskinetic PD group compared to controls. The findings highlight the potential role of the examined biomarkers in the pathophysiology of PD. Changes in levels of the tested inflammatory biomarkers and adipokines might be associated with Parkinson’s disease and its symptoms such as dyskinesia.
Metabolic Profiling of Aromatic Compounds
Authors: Pautova Alisa K.
Published: February 2024

Metabolic profiling is a powerful modern tool in searching for novel biomarkers and indicators of normal or pathological processes in the body [...]
Experimental Study on the Skyhook Control of a Magnetorheological Torsional Vibration Damper
Authors: Wang Zhicheng , Hu Hongsheng , Yang Jiabin , Zheng Jiajia , Zhao Wei , Ouyang Qing
Published: February 2024

This study proposes a dual-coil magnetorheological torsional vibration damper (MRTVD) and verifies the effectiveness of semi-active damping control to suppress the shaft system’s torsional vibration via experimental research. Firstly, the mechanical model of the designed MRTVD and its coupling mechanical model with the rotating shaft system are established. Secondly, the torsional response of the shaft system is obtained via resonance experiments, and the influence of the current on the torsional characteristics of the magnetorheological torsional damper is analyzed. Finally, the MRTVD is controlled using the skyhook control approach. The experimental results demonstrate that when the main shaft passes through the critical speed range at various accelerations, the amplitude of the shaft’s torsional vibration decreases by more than 15%, and the amplitude of the shaft’s torsional angular acceleration decreases by more than 22%. These conclusions validate the inhibitory effect of MRTVD on the main shaft’s torsional vibrations under skyhook control.
Application of Acetate as a Substrate for the Production of Value-Added Chemicals in Escherichia coli
Authors: Gu Pengfei , Li Fangfang , Huang Zhaosong , Gao Juan
Published: February 2024

At present, the production of the majority of valuable chemicals is dependent on the microbial fermentation of carbohydrate substrates. However, direct competition is a potential problem for microbial feedstocks that are also used within the food/feed industries. The use of alternative carbon sources, such as acetate, has therefore become a research focus. As a common organic acid, acetate can be generated from lignocellulosic biomass and C1 gases, as well as being a major byproduct in microbial fermentation, especially in the presence of an excess carbon source. As a model microorganism, Escherichia coli has been widely applied in the production of valuable chemicals using different carbon sources. Recently, several valuable chemicals (e.g., succinic acid, itaconic acid, isobutanol, and mevalonic acid) have been investigated for synthesis in E. coli using acetate as the sole carbon source. In this review, we summarize the acetate metabolic pathway in E. coli and recent research into the microbial production of chemical compounds in E. coli using acetate as the carbon source. Although microbial synthetic pathways for different compounds have been developed in E. coli, the production titer and yield are insufficient for commercial applications. Finally, we discuss the development prospects and challenges of using acetate for microbial fermentation.
Seed-Borne Bacterial Diversity of Fescue (Festuca ovina L.) and Properties Study
Authors: Zhu Shaowei , Xie Jinjing , Yang Jie , Hou Xuan , He Linxin , Zhang Zhenfen
Published: February 2024

Rich endophytic bacterial communities exist in fescue (Festuca ovina L.) and play an important role in fescue growth, cold tolerance, drought tolerance and antibiotic tolerance. To screen for probiotics carried by fescue seeds, seven varieties were collected from three different regions of China for isolation by the milled seed method and analyzed for diversity and motility, biofilm and antibiotic resistance. A total of 91 bacterial isolates were obtained, and based on morphological characteristics, 36 representative dominant strains were selected for 16S rDNA sequencing analysis. The results showed that the 36 bacterial strains belonged to four phyla and nine genera. The Firmicutes was the dominant phylum, and Bacillus, Paenibacillus and Pseudomonas were the dominant genera. Most of the strains had motility (80%) and were biofilm-forming (91.7%). In this study, 15 strains were capable of Indole-3-acetic acid (IAA) production, 24 strains were capable of nitrogen fixation, and some strains possessed amylase and protease activities, suggesting their potential for growth promotion. Determination of the minimum inhibitory concentration (MIC) against the bacteria showed that the strains were not resistant to tetracycline and oxytetracycline. Pantoea (QY6, LH4, MS2) and Curtobacterium (YY4) showed resistance to five antibiotics (ampicillin, kanamycin, erythromycin, sulfadiazine and rifampicin). Using Pearson correlation analysis, a significant correlation was found between motility and biofilm, and between biofilm and sulfadiazine. In this study, we screened two strains of Pantoea (QY6, LH4) with excellent growth-promoting ability as well as broad-spectrum antibiotic resistance. which provided new perspectives for subsequent studies on the strong ecological adaptations of fescue, and mycorrhizal resources for endophytic bacteria and plant interactions.
Gold Nanoparticles Bioproduced in Cyanobacteria in the Initial Phase Opened an Avenue for the Discovery of Corresponding Cerium Nanoparticles
Authors: Fritz Melanie , Chen Xiaochen , Yang Guifang , Lv Yuancai , Liu Minghua , Wehner Stefan , Fischer Christian B.
Published: February 2024

The production of isolated metallic nanoparticles with multifunctionalized properties, such as size and shape, is crucial for biomedical, photocatalytic, and energy storage or remediation applications. This study investigates the initial particle formations of gold nanoparticles (AuNPs) bioproduced in the cyanobacteria Anabaena sp. using high-resolution transmission electron microscopy images for digital image analysis. The developed method enabled the discovery of cerium nanoparticles (CeNPs), which were biosynthesized in the cyanobacteria Calothrix desertica. The particle size distributions for AuNPs and CeNPs were analyzed. After 10 h, the average equivalent circular diameter for AuNPs was 4.8 nm, while for CeNPs, it was approximately 5.2 nm after 25 h. The initial shape of AuNPs was sub-round to round, while the shape of CeNPs was more roundish due to their amorphous structure and formation restricted to heterocysts. The local PSDs indicate that the maturation of AuNPs begins in the middle of vegetative cells and near the cell membrane, compared to the other regions of the cell.
Mesozoic and Cenozoic Tectono-Thermal Reconstruction of the Southern Ordos Basin: Revealed by Apatite Fission Track and (U-Th)/He Dating
Authors: Gao Peng , Hu Jie , Hu Shengbiao
Published: February 2024

The Ordos Basin is rich in oil and gas resources in the Paleozoic strata. The southern part of the basin boasts a thick Paleozoic sedimentary sequence, enriched organic matter, favorable sedimentary facies, and hydrocarbon source rocks with an over-mature thermal evolution stage. However, the lack of in-depth study of the tectono-thermal evolution in the southern basin limits regional oil and gas exploration. In this study, drill core and outcrop samples were collected from the Shanbei Slope and the Weibei Uplift, respectively. These samples were subjected to apatite fission track (AFT) and (U-Th)/He dating (AHe). The results were used to reconstruct the thermal history of the southern basin, calculate exhumation rates, and analyze the tectonic evolution of the basin. The seven annealed AFT data values from the Shanbei Slope range from 21.4 to 52.8 Ma, with mean track lengths of 13.24 μm, and the twelve unannealed AFT data values from the Weibei Uplift range from 111.9 to 204.6 Ma. The seven AHe data values from the Shanbei Slope range from 17.0 to 31.8 Ma, and the eight AHe data values from the Weibei Uplift range from 31.7 to 47.5 Ma. The thermal history is characterized by a prolonged phase of burial and heating from the Triassic to the Late Early Cretaceous, followed by a phase of uplift and cooling that continued into the Cenozoic. This cooling phase exhibits three distinct stages with varying rates of uplift and cooling. According to the dating results, the cooling timing of the southern basin was earlier than that of the central part, and the southern basin experienced higher uplift rates during the Paleogene than in other periods of the Cenozoic. This may be attributed to the far-field effects of the collision between the Indian Plate and the Eurasian Plate during the Paleogene.
Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis—A Randomized Pilot Study
Authors: Fishman Loren
Published: February 2024

Background: Approximately 90% of scoliosis cases are adolescent-idiopathic (AIS). From the first appearance of scoliosis at 10–14 years of age until the age of 18, the spine is most vulnerable to deterioration; young, growing people are most susceptible to the worsening of one or more scoliotic curves. An effective non-surgical means of remediation would be welcome. Design: This was a randomized, controlled, two-arm study assessing the safety and efficacy of combining incobotulinum injections with yoga to reverse lumbar and thoracolumbar AIS. Methods: In a private clinic setting, non-pregnant, healthy 12–18 year-olds were either taught a symmetrical “placebo” yoga pose (control sub-group 1), performed the side plank (Vasisthasana) three times daily with a placebo injection (control sub-group 2) or performed the three-times-daily side plank with a botulinum injection (intervention group 3). Injection: For the injection, 33 IU of incobotulinumtoxin type A (Xeomin) was injected into the concave-side lumbar paraspinals and quadratus lumborum at L2–3 and the psoas muscle at L3–4, or participants were injected similarly with a placebo. Randomization was achieved using random.org. Objective: The objective was to determine whether the treatment of muscular asymmetry with botulinum toxin injections and side planks is safe and effective in AIS. Results/Outcome: Eleven intervention and thirteen placebo patients (Groups 1 + 2), who were 12–18 years old, completed the three-month study. Mean daily side plank time = 165 s. The mean initial lumbar curvature was 36.9 degrees (SD 14.36), (p < 0.0001); the mean Group 3 curvature at 3 weeks was 29.5 degrees (SD 14.23) (p < 0.0001); and the mean Group 3 curvature at 3 months was 26.0 degrees (SD 12.81). Onset vs. 3-month value: p < 0.0001. Harms were limited to one patient in Group 2 and one in Group 3, who complained of transient shoulder pain and supported themselves temporarily on their forearm instead of the palm of the extended hand. Conclusion: Muscle strength asymmetry appears to be relevant to AIS treatment. Incobotulinum injections combined with side planks performed with the convex side downward may be more effective in reversing lumbar AIS than placebo exercises or side planks and placebo injections.
Series-Biased Micro-LED Array for Lighting, Detection, and Optical Communication
Authors: Fang Qian , Feng Xiaoxiao , Yin Huiping , Shi Zheng , Qin Feifei , Wang Yongjin , Li Xin
Published: February 2024

Micro-LED arrays exhibit high brightness, a long lifespan, low power consumption, and a fast response speed. In this paper, we have proposed a series-biased micro-LED array by using a nitride layer with multi-quantum wells epitaxial on sapphire substrate. The III-nitride multiple quantum wells serving as the micro-LED active material enable both luminescence and detection functionalities. The micro-LED array combines lighting, detection, and communication capabilities. We have conducted a thorough analysis of the micro-LED array’s optoelectronic features in both lighting and detection modes. We also explore visible light communication performance across different arrangements of single micro-LED devices within the series-biased array. Our research achieves 720p video transmission via visible light communication using the micro-LED array, supporting a communication rate of up to 10 Mbps. Our contributions encompass the successful integration of lighting and detection functions and a comprehensive assessment of optoelectronic and communication performance. This study highlights the multifunctional micro-LED array’s potential as a transceiver terminal in visible light communication systems, expanding its applications from smart lighting to visible light communication and photonic integrated chips. These innovations enhance our understanding of micro-LED technology and its versatile applications.
Dynamics of Elliptical Magnetic Skyrmion in Defective Racetrack
Authors: Zhu Huangkun , Xiang Gang , Feng Youhua , Zhang Xi
Published: February 2024

Recently, it has been reported that the skyrmion Hall effect can be suppressed in an elliptical skyrmion-based device. Given that defects are unavoidable in materials, it is necessary and important to investigate the dynamics of an elliptical skyrmion in a defective racetrack device. In this work, the current-driven dynamics of an elliptical skyrmion in a defective racetrack device are systematically studied using micromagnetic simulations. The system energy analysis reveals that the magnetic parameters of the circular defect play critical roles in determining the type (repulsive or attractive) and the magnitude of the force on the elliptical skyrmion. The simulated trajectories show that the primary motion modes of the elliptical skyrmion in the defective racetrack can be divided into four types, which are dependent on the values of the Dzyaloshinskii–Moriya interaction (DMI) constant Dd, the perpendicular magnetic anisotropy constant Kd, the magnitude of the driving current density J, and the size d of the defect. Further investigation of the motion-mode phases of the skyrmion reveals the synthetic effects of Dd, Kd, J, and d. Finally, the minimum depinning current density J, which linearly depends on the parameters of Dd and Kd, is obtained for a skyrmion completely pinned in the defect. Our findings give insights into the dynamics of an elliptical skyrmion in the presence of a defect with different magnetic parameters in a racetrack device and may be useful for performance enhancement of skyrmion-based racetrack memory devices.
Novel Ag-Bridged Z-Scheme CdS/Ag/Bi2WO6 Heterojunction: Excellent Photocatalytic Performance and Insight into the Underlying Mechanism
Authors: Wang Fangzhi , Jiang Lihua , Zhang Guizhai , Ye Zixian , He Qiuyue , Li Jing , Li Peng , Chen Yan , Zhou Xiaoyan , Shang Ran
Published: February 2024

The construction of semiconductor heterojunction photocatalysts that improve the separation and transfer of photoinduced charge carriers is an effective and widely employed strategy to boost photocatalytic performance. Herein, we have successfully constructed a CdS/Ag/Bi2WO6 Z-scheme heterojunction with an Ag-bridge as an effective charge transfer channel by a facile process. The heterostructure consists of both CdS and Ag nanoparticles anchored on the surface of Bi2WO6 nanosheets. The photocatalytic efficiency of the CdS/Ag/Bi2WO6 system was studied by the decontamination of tetracycline (TC) and Rhodamine B (RhB) under visible light irradiation (λ ≥ 420). The results exhibited that CdS/Ag/Bi2WO6 shows markedly higher photocatalytic performance than that of CdS, Bi2WO6, Ag/Bi2WO6, and CdS/Bi2WO6. The trapping experiment results verified that the •O2− and h+ radicals are the key active species. The results of photoluminescence spectral analysis and photocurrent responses indicated that the CdS/Ag/Bi2WO6 heterojunctions exhibit exceptional efficiency in separating and transferring photoinduced electron−hole pairs. Based on a series of characterization results, the boosted photocatalytic activity of the CdS/Ag/Bi2WO6 system is mostly due to the successful formation of the Ag-bridged Z-scheme heterojunction; these can not only inhibit the recombination rate of photoinduced charge carriers but also possess a splendid redox capacity. The work provides a way for designing a Z-scheme photocatalytic system based on Ag-bridged for boosting photocatalytic performance.
Series Solutions of Three-Dimensional Magnetohydrodynamic Hybrid Nanofluid Flow and Heat Transfer
Authors: You Xiangcheng , Wang Yanbin
Published: February 2024

Hybrid nanofluids have many real-world applications. Research has shown that mixed nanofluids facilitate heat transfer better than nanofluids with one type of nanoparticle. New applications for this type of material include microfluidics, dynamic sealing, and heat dissipation. In this study, we began by placing copper into H2O to prepare a Cu-H2O nanofluid. Next, Cu-H2O was combined with Al2O3 to create a Cu-Al2O3-H2O hybrid nanofluid. In this article, we present an analytical study of the estimated flows and heat transfer of incompressible three-dimensional magnetohydrodynamic hybrid nanofluids in the boundary layer. The application of similarity transformations converts the interconnected governing partial differential equations of the problem into a set of ordinary differential equations. Utilizing the homotopy analysis method (HAM), a uniformly effective series solution was obtained for the entire spatial region of 0 < η < ∞. The errors in the HAM calculation are smaller than 1 × 10−9 when compared to the results from the references. The volume fractions of the hybrid nanofluid and magnetic fields have significant impacts on the velocity and temperature profiles. The appearance of magnetic fields can alter the properties of hybrid nanofluids, thereby altering the local reduced friction coefficient and Nusselt numbers. As the volume fractions of nanoparticles increase, the effective viscosity of the hybrid nanofluid typically increases, resulting in an increase in the local skin friction coefficient. The increased interaction between the nanoparticles in the hybrid nanofluid leads to a decrease in the Nusselt number distribution.
Missense Variants in COL4A1/2 Are Associated with Cerebral Aneurysms: A Case Report and Literature Review
Authors: Uemura Masahiro , Tanaka Natsuki , Ando Shoichiro , Yanagihara Takehiko , Onodera Osamu
Published: February 2024

Background: Although cerebral aneurysm (CA) is a defining complication of COL4A1/2-related vasculopathy, the specific factors influencing its onset remain uncertain. This study aimed to identify and analyze these factors. Methods: We described a family presenting with a novel variant of the COL4A1 gene complicated with CA. Concurrently, an exhaustive review of previously documented patients with COL4A1/2-related vasculopathy was conducted by sourcing data from PubMed, Web of Science, Google Scholar, and Ichushi databases. We compared the variant types and locations between patients with CA (positive group) and those without CA (negative group). Results: This study included 53 COL4A1/2 variants from 76 patients. Except for one start codon variant, all the identified variants in CA were missense variants. Otherwise, CA was not associated with other clinical manifestations, such as small-vessel disease or other large-vessel abnormalities. A higher frequency of missense variants (95.5% vs. 58.1%, p = 0.0035) was identified in the CA-positive group. Conclusions: CA development appears to necessitate qualitative alterations in COL4A1/2, and the underlying mechanism seems independent of small-vessel disease or other large-vessel anomalies. Our findings suggest that a meticulous evaluation of CA is necessary when missense variants in COL4A1/2 are identified.
Longitudinal Associations of Food Security with Health and Dietary Factors among Food FARMacy Participants during COVID-19 in New York City
Authors: Woo Baidal Jennifer , Finkel Morgan A. , Kelman Elizabeth , Duong Ngoc , Bien-Aime Celine , Goldsmith Jeff , Albrecht Sandra S. , Hulse Emma , Rosenthal Alyson , Reiss Jeremy , Schwartz Rachel , Meyer Dodi ,   on behalf of the HERALD Collaborative
Published: February 2024

In cross-sectional studies, food insecurity is associated with adverse health and dietary outcomes. Whether self-reported health and dietary outcomes change in response to improvements in food security has not been examined. We sought to examine how increases in food security are related to changes in health and dietary factors. In this longitudinal, observational study, we included adult participants in a clinical-community emergency food assistance program in New York City from July 2020 to November 2021. Program staff measured food security with a validated six-item measure at program enrollment and six-month re-enrollment. Participants self-reported health and dietary factors (vegetable, fruit, juice, and sugar-sweetened beverage (SSB) consumption frequency). We used multivariable regression to examine associations between change in food security with change in health and dietary factors over six months. Among 310 participants, the mean food security score improved by 1.7 ± 2.3 points over six months. In unadjusted models, each point improvement in food security was associated with increased vegetable (β = 0.10 times; 95% CI: 0.05–0.15); fruit (β = 0.08 times; 95% CI: 0.03–0.14); and juice (β = 0.10 times; 95% CI: 0.05–0.15) consumption. In adjusted models, results remained significant for vegetable and fruit consumption, but not juice. Change in food security was not associated with change in health or SSB outcomes. In this cohort during COVID-19, improved food security was associated with improved vegetable and fruit consumption. Randomized trials that examine the effectiveness of clinical-community partnerships focused on improving food security and nutrition are warranted.