bluuebunny/crossref_metadata_2025 huggingface dataset:
Predicting Translation Students' Cultural Intelligence through Different Types of Creativity
Authors: Sadrnia Pouria , Shahnazari Mohammadtaghi
Published: May 2023

Translators are reputed to work not only within languages but also across cultures. Intercultural interactions can be carried out when the translator is creative enough. The present paper intends to determine the pivotal types of creativity which can predict the translators' cultural intelligence in cross-cultural interaction. 103 translation students were chosen to participate in the study through convenient sampling. Kaufman Scale of Creativity (2012) and Cultural Intelligence Scale (2007) were administered to measure participants' types of creativity and cultural intelligence. Results of the Pearson correlation attested that the Kaufman scale of creativity is moderately correlated with the cultural intelligence scale. Multiple regression analysis revealed that among the different components of creativity, scholarly, self, and artistic were the best predictors of translation students' cultural intelligence. Implications of the study for translation training courses and professional translation agencies are advised to introduce the idea of creative types in training or hiring translators.
Keywords: Cultural intelligence, Kaufman creativity types, Self-creativity, Scholarly, Artistic
TOPF MONGE, Guiomar. Traducir el género. Aproximación feminista a las traducciones españolas de obras de Annemarie Schwarzenbach. Berlín, Peter Lang, 2020, 316 pp., ISBN 978-36-318-3260-8
Authors: Álvarez Sánchez Patricia
Published: May 2023

.
Características de la explicitación de las relaciones lógicas en la traducción del chino al español y sus motivaciones
Authors: Li Jing
Published: May 2023

Este trabajo busca comprobar la explicitación en la traducción al español de la obra Rana del autor chino Mo Yan, ganador del Premio Nobel de Literatura 2012, revelar sus características y descifrar las motivaciones del fenómeno. Se ha utilizado el método cuantitativo basado en corpus para describir, por un lado, el uso de las conjunciones lógicas en el texto meta y su correspondencia con el texto fuente; y por el otro, la traducción al español de las oraciones con una relación lógica explícita en el original. El resultado muestra que la explicitación es más relevante que la implicitación en el conjunto de las relaciones lógicas, en cada tipo de relación y en cada conjunción. Asimismo, el grado de explicitación disminuye en las relaciones lógicas causales, consecutivas, condicionales, adversativas y concesivas, mientras los conectores de la misma categoría presentan distintos grados de explicitación. Se han analizado las motivaciones de la explicitación desde una perspectiva lingüística y del traductor. Las divergencias entre el chino y el español en la organización del texto y la explicación del traductor influyen en la explicitación. Las diferencias entre los dos idiomas en la frecuencia de uso de las cuatro categorías de relación y de los conectores, así como la subjetividad del traductor, generan que las relaciones y conectores presenten diferentes grados de explicitación.
EMILY, Rose. Translating Trans Identity. (Re)writing Undecidable Texts and Bodies. Nueva York y Londres, Routledge, 2021, 215 pp., ISBN 978-0-367-36996-5
Authors: Iturregui Gallardo Gonzalo
Published: May 2023

.
SOCIOECONOMIC DEVELOPMENT IN MUSLIM COUNTRIES: IBN KHALDUN’S DEVELOPMENT MODEL-BASED APPROACH
Authors: Pratiwi Ira Eka
Published: May 2023

This study constructs a measure of socioeconomic development in Muslim countries based on Ibn Khaldun’s model of development.  It proposes a composite index of development based on three dimensions, namely human empowerment, government and institution, and economic growth, and terms it as Ibn Khaldun-based socioeconomic development index (I-SDI). A total of 13 indicators are selected to represent each dimension and are employed for construction of the index using an equal weighted method and additive aggregation approach.  In generally, we note that many Muslim countries are underperformed., as indicated by the low value of I-SDI.   We further find that Muslim countries that perform well in government and institution dimensions tend to experience better socioeconomic development.  We believe that the proposed I-SDI is non-redundant and robust and hence can be utilized as an alternative way of measuring the development in Muslim countries. In other words, the Ibn Khaldun’s model of development is exceptionally meaningful in explaining the socio-economic performance of Muslim countries.
MUSLIM WOMEN SWITCHING INTENTION TO HALAL COSMETIC: PUSH-PULL-MOORING MODEL APLICATION
Authors: Pambekti Galuh Tri , Nugraha Septy Setia , Yusfiarto Rizaldi
Published: May 2023

This study focuses on the factors that contribute to switching intentions from non-halal cosmetics to halal cosmetics by Muslim women in Indonesia. Using a questionnaire and purposive sampling, we compile data from a total of 236 women who use halal cosmetics and then apply the SEM-PLS for data analysis. The results show that the pull effect significantly affects Muslim women's intention to switch to halal cosmetics and is moderated negatively by switching costs. While the push effect doesn’t significantly affect the intention to switch to halal cosmetics. In addition, halal awareness and switching costs directly affect Muslim women's switching intentions from non-halal to halal cosmetics.
FINANCIAL SUSTAINABILITY OF A FIRM: DEBT-BASED OR EQUITY-BASED FINANCING TO PURSUE?
Authors: Sha'ari Umul Ain'syah , Hamzah Siti Raihana Bt , Kamil Karmila Hanim
Published: May 2023

This study examines the potential of utilizing equity-based financing by companies in achieving financial sustainability as compared to debt-based financing. To this end, a conceptual framework of equity-based financing over debt-based financing is developed to provide an understanding of the concept of equity-based financing. Subsequently, this study analyses the credit risk exposure between equity and debt for selected sectors in Malaysia.  More specifically, a Monte Carlo method is employed to examine the feasibility of the equity-based financing model in fostering the financial sustainability of companies through simulation of equity-based and debt-based financing models from the global financial crisis (GFC) period to the Covid-19 phase. This study finds that equity-based financing can reduce credit risk exposure when returns are tied to the company’s performance. The findings also show that equity-based financing can achieve financial sustainability regardless of any economic events. To conclude, equity-based financing can thus be a viable capital financing option for companies because it can contribute to long-term financial sustainability.
Sobre escolhas difíceis: uma análise dialógica da política brasileira em editoriais
Authors: Oliveira Fábio Augusto Alves de
Published: May 2023

Este trabalho, pautado nos estudos bakhtinianos, trata das posições do Estado de S.P e do Le Monde sobre as eleições presidenciais em 2018. Enunciado é o conceito teórico de análise, com o qual se discute a arquitetura social dos atos de linguagem. Dois editoriais referentes ao contexto eleitoral são selecionados como objeto de análise. O objetivo, por sua vez, é compreender o posicionamento e a interpretação dos jornais na tensão política. Os enunciados se confrontam e disputam a significação de “escolha” e suas situações políticas. A justificativa do artigo é estudar, por meio da teoria bakhtiniana, um momento tenso e relevante para o contexto político no Brasil. Palavras-chave: estudos bakhtinianos; política brasileira; imprensa; enunciado.
Neurociências e dificuldades de escrita: o contradiscurso da Neurolinguística Discursiva
Authors: Moutinho Isabella de Cássia Netto
Published: May 2023

Este artigo apresenta o contradiscurso da Neurolinguística Discursiva sobre um manual de intervenção clínica e pedagógica na escrita de crianças com dificuldades escolares. Este manual é representativo do discurso neurocientífico, tendência teórica dos estudos da educação para a compreensão do processo de alfabetização. Partindo de uma metodologia heurística de análise de dados, apresento o contraste entre a intervenção discursivamente orientada e a intervenção neurocientífica, questionando se ela é, de fato, inovadora, e se ajuda o investigador/alfabetizador a compreender quais são as dificuldades das crianças, bem como seu trabalho linguístico-cognitivo no ato da escrita.Palavras-chave: neurolinguística discursiva; neurociência; dificuldades escolares.
Recursos metadiscursivos em “A loucura epidêmica de Canudos”, de Raimundo Nina Rodrigues
Authors: Oliveira Kauê Uematsu de
Published: May 2023

Neste artigo, analiso recursos metadiscursivos no texto “A loucura epidêmica de Canudos” (1897), de Raimundo Nina Rodrigues (1867-1906). Partindo dos estudos de letramento acadêmico (LEA; STREET, 2006), trabalho com a distinção proposta por Ken Hyland entre recursos interativos e interacionais. Elementos interativos dizem respeito a como o autor manipula informação para o estabelecimento de suas interpretações em interação com uma comunidade de sentido, enquanto os elementos interacionais estão centrados em sua intervenção explícita, como ao julgar abertamente seu próprio discurso (HYLAND, 2005). Assim, os recursos metadiscursivos, ao marcarem a posição do autor em relação a outros dizeres e à comunidade a que pertence, conectam texto e contexto, sendo produtivos para a investigação de padrões de interação e construção de efeitos de verdade em textos acadêmicos.Palavras-chave: letramento acadêmico; metadiscurso; Nina Rodrigues.
Os discursos conservador e neoliberal na fala de Bolsonaro
Authors: Antunes Mait Paredes
Published: May 2023

A primeira resposta de Jair Bolsonaro no programa Roda Viva, de 30 de julho de 2018, revela as matrizes ideológicas conservadora e neoliberal, cuja análise é feita neste trabalho a partir dos conceitos de discurso e ideologia, como desenvolvidos pelo Círculo de Bakhtin. Na fala, os posicionamentos sócioideológicos relacionam-se com o contexto de produção dessas ideologias. Tal contexto refere-se à expansão neoliberal em países de centro e periferia. A hipótese que se levanta é a de que tais matrizes não são contraditórias entre si, mas necessárias uma à outra. Então, é traçado um breve percurso do neoliberalismo; conclui-se que tanto o discurso conservador quanto o neoliberal, presentes na fala de Bolsonaro, possuem uma lógica interna e um programa, consonantes ao contexto e articuladores de sentidos sociais, como o recrudescimento da violência e o fim da possibilidade de conciliação entre Estado, trabalho e capital. Palavras-chave: Jair Bolsonaro; neoliberalismo; análise sociológica do discurso.
Diversidade cultural da língua espanhola em ações de extensão na pandemia: contribuições para a internacionalização
Authors: Stefani Viviane Cristina Garcia de
Published: May 2023

Este artigo objetiva apresentar alguns resultados do projeto de extensão “Diversidade Cultural: expandindo culturas por meio do espanhol”, desenvolvido em um campus do Instituto Federal de Educação, Ciência e Tecnologia de São Paulo (IFSP). As ações do projeto (que incluem sarau cultural e cinedebate virtuais) foram todas realizadas virtualmente e visaram despertar o interesse pela aprendizagem do idioma por meio de atividades cuja finalidade é o conhecimento sobre a diversidade cultural dos países hispanofalantes. Fundamentados por teorias que definem o processo de internacionalização na educação (HUDZIK, 2011; DE WIT, 2013), demonstramos de que forma ações de extensão dessa natureza podem contribuir fortemente para esse processo. Os resultados mostraram que o projeto contribuiu para fomentar ações de internacionalização no âmbito da extensão, além de estimular o interesse pelo aprendizado da língua e cultura. Palavras-chave: espanhol; extensão; internacionalização; diversidade cultural.
Cloroquina ou tubaína? Piadas presidenciais sobre a pandemia
Authors: Carmelino Ana Cristina
Published: May 2023

A proposta deste artigo é analisar duas frases humorísticas do presidente do Brasil, Jair Bolsonaro, sobre a pandemia, buscando refletir quanto ao funcionamento delas. Tais frases, proferidas publicamente e veiculadas na imprensa, foram consideradas piadas. Parte-se da hipótese de que esses enunciados configuram piadas conversacionais e que, nesses casos, a utilização discursiva do humor funcionou como uma estratégia para desqualificar orientações de autoridades científicas sobre o controle da doença. O estudo se ancora nos pressupostos teóricos de Norrick (1993) sobre piada conversacional e em estudiosos do humor, entre os quais Freud (1996), Propp (1992) e Goméz (2014). O exame dos dados revela que o uso do humor, por meio dos enunciados espontâneos e informais do presidente, é um meio de ridicularizar e, por consequência, desacreditar o discurso científico sobre o coronavírus.Palavras-chave: humor; piada conversacional; pandemia; Bolsonaro.
O conceito de fala no manuscrito “Essência Dupla da Linguagem” e no Curso de Linguística Geral: um estudo comparativo
Authors: Giembinsky Mariane
Published: May 2023

Neste estudo, pretendemos analisar o conceito de fala de forma a comparar o que apresenta o manuscrito “Essência Dupla da linguagem” (EDL) ao que será depois colocado no Curso de Linguística Geral (CLG). Assim, questionamos o que se mantém e o que se distingue do pensamento em construção na edição do CLG. Sabemos da importância da distinção entre língua e fala concretizada no CLG e essa construção teórica terá ênfase neste trabalho. Diante dessa questão, levantamos a hipótese de que, apesar de não conceitualizar a fala no manuscrito EDL, Saussure apresenta termos que remetem a ela e que posteriormente serão observados de forma mais clara e objetiva no CLG. Essa hipótese será apresentada em dois momentos durante o artigo: i) Saussure não conceitualiza o conceito de fala no manuscrito EDL. Ele apresenta termos no manuscrito que remetem ao conceito de fala e ii) é possível verificar no CLG o conceito de fala de forma mais objetiva do que no manuscrito. Dessa forma, o método comparativo entre os materiais favorecerá a emergência das diferenças e a análise contrastiva nos permitirá evidenciar o percurso de elaboração do conceito de fala por Ferdinand de Saussure.Palavras-chave: manuscrito; fala; CLG.
A vergonha e o orgulho em memes sobre a leitura
Authors: Silva Jeniffer Aparecida Pereira da , Ferreira Luzmara Curcino
Published: May 2023

De modo a contribuir com os estudos dedicados à leitura e às formas como essa prática é comumente referida entre nós, apresentamos, neste artigo, uma análise de enunciados peculiares, coletados junto a memes de internet que abordam o tema da leitura e nos quais se evocam certas emoções quando se fala acerca dessa prática. Observamos, com base em princípios da Análise do discurso, da História cultural da leitura e da História das sensibilidades, que a “vergonha” e o “orgulho” relacionados à condição leitora compõem as emoções prototípicas constitutivas dos discursos sobre a leitura mais frequentemente atualizados em memes nacionais e contemporâneos.Palavras-chave: discursos sobre a leitura; memes; emoções; vergonha; orgulho.
Sollertínski e a filosofia bakhtiniana da linguagem: uma leitura introdutória contributiva
Authors: Luciano José Antonio Rodrigues
Published: May 2023

Este artigo propõe expor, de maneira introdutória, os estudos de Ivan Sollertínski, renomado musicólogo da União Soviética e importante membro do Círculo “Bakhtin, Medviédev, Volóchinov [B.M.V.]” (VAUTHIER, 2010). O objetivo é apresentar, ineditamente à recepção brasileira, esse pensador russo, a partir da: a) localização das suas obras publicadas na Rússia; b) reflexão sobre a sua recepção no Ocidente, ao indicar a tradução de textos em línguas neolatinas (inglês e italiano, especificamente); c) formulação de algumas ideias centrais; e d) contribuição para a construção da concepção tridimensional da linguagem, denominada verbivocovisual (PAULA, 2017; LUCIANO, 2021), na filosofia bakhtiniana. Com isso, esperamos introduzir os textos de Sollertínski nas pesquisas bakhtinianas no Brasil, expandindo o conhecimento sobre o Círculo e lançando nova luz à proposta filosófica do coletivo pensante russo, em especial, à concepção de linguagem.Palavras-chave: Círculo “Bakhtin, Medviédev e Volóchinov”; Sollertínski; verbivocovisualidade.
Hyperspectral Confocal Imaging for High-Throughput Readout and Analysis of Bio-Integrated Laser Particles
Authors: Titze Vera M , Caixeiro Soraya , Dinh Vinh San , König Matthias , Rübsam Matthias , Pathak Nachiket , Niessen Carien M , Schubert Marcel , Gather Malte C
Published: May 2023

Integrating laser particles into live cells, tissue cultures, and small animals is an emerging and rapidly evolving technique that offers non-invasive interrogation and labelling with unprecedented information density. The bright and distinct spectra of laser particles make this approach particularly attractive for high-throughput applications requiring single-cell specificity, such as multiplexed cell tracking and intracellular biosensing. To be of practical relevance, the implementation of these applications requires high-resolution, high-speed spectral readout and advanced analysis routines, which leads to unique technical challenges. Here, we present a modular protocol consisting of two separate procedures. The first part of our protocol instructs users on how to efficiently integrate different types of laser particles into living cells. The second part presents a workflow for obtaining intracellular lasing spectra with high spectral resolution and up to 125 kHz readout rate and starts from the construction of a custom hyperspectral confocal microscope. We provide guidance on running hyperspectral imaging routines for various experimental design choices and recommend specific workflows for processing the resulting large data sets along with an open-source Python library of functions covering the entire analysis pipeline. The results one can obtain using this protocol are illustrated with three representative experiments: Rapid, large-volume mapping of absolute refractive index using polystyrene microbead laser particles, intracellular sensing to monitor cardiac contractility with polystyrene microbead laser particles, and long-term cell tracking using semiconductor nanodisk laser particles. Our sample preparation and imaging procedures can be completed within two days. Setting up the hyperspectral confocal microscope for laser particle characterization will take users with little prior experience in optical and software engineering <2 weeks to complete.
Gender as a determinant of health in under-five children in Ethiopia; a secondary data analysis from EDHS 2016
Authors: Ketema Elbet , Hassen Saria
Published: May 2023

Background: Under-five mortality is one of the key sustainable
development goal targets. Despite the great strides made globally,
Under-five mortality remains high in many developing countries like
Ethiopia. Child health status is determined by a myriad of factors
at the individual, family and community level, furthermore, a
child’s gender has been shown to affect the probability of infant
and child mortality.

Methods: A secondary data analysis was conducted using
Ethiopian demographic health survey 2016 to assess association
between gender and under-five child health. A representative sample
of 18,008 households was selected. After data cleaning and entry,
analysis was done using the Statistical Package for Social Sciences
(SPSS) version 23. Uni-variable and multivariable logistic
regression model were employed to determine the association between
under-five child health and gender. In the final multivariable
logistic regression model, the association of gender with childhood
mortality was declared statistically significant at P value<
0.05.

Result: A total of 2,075 under five children from EDHS 2016 were included in the analysis. Majority (92%) were rural dwellers. More male children were found to be underweight (53% Vs 47%) and wasted (56.2% Vs 43.8%) compared to female children. A higher proportions of females were vaccinated (52.2%) compared to 47.8% in males. Health seeking behavior for fever (54.4%) and diarrheal diseases (51.6%) were also found to be higher for females. However, in a multivariable logistic regression model, there was no statistically significant association found between gender and under-five child children health measures.
Conclusion: Although it was not statistically significant association, females were found to have a better health and nutritional outcomes compared to boys in our study.
Reducing continuous synchrony is an inherent property of tree growth in forests
Authors: Zhang Qi-Bin , Jia Hengfeng , Zheng Jiacheng , Fang Ouya , Yang Jing , Langzhen Jia-Yang , Hebda Richard J.
Published: May 2023

Forests play an important role in providing ecosystem services and regulating carbon balance. Modelers rely on the implicit assumption that, under the common climate drivers, trees have similar growth patterns over large spatial scale. Using ring-width sequences of 1046 juniper trees from Tibetan Plateau and 538 pine trees in the eastern China, we show that, although tree growth is influenced by climatic factors, individual trees often do not respond in a synchronous manner. After highly synchronous growth events, the number of trees exhibiting common growth change declined progressively and, notably, the patterns of decline exhibited the form of exponential function with parameter of base b ranging from 0.57-0.83 for juniper forests in Tibetan Plateau and from 0.56-0.72 for pine forests in eastern China. Our findings suggest that individual trees in forests tend to grow independently with respect to climate rather than synchronously, and that a relatively uniform pattern of growth de-synchronization is an inherent property of forest tree growth. We propose that this property is essential for trees collectively to have resilience and maintain forest stability, analogous to maintaining a diverse investment portfolio as a strategy to cope with unexpected risks. This new perspective on widespread non-synchronous radial tree growth sheds insight into fundamental ecological processes in forest resilience and can improve assessment and management of forest health risks under future climate change.
Investigation of Performance Properties of Wool Fabrics Treated with Bromelain from Pineapple Peel Wastes
Authors: Açıkgöz Sena , Keleş Banu Özgen , Okutucu Burcu
Published: May 2023

The pilling and shrinkage of wool fabrics are major problems in the textile industry. Chemical treatments are used to improve the performance properties of wool fabrics. These chemical processes severely pollute the ecosystem. This study is aimed to use bromelain isolated from pineapple peel waste instead of toxic chemicals used during pretreatments to prevent shrinkage and minimize pilling in the woolen textile industry. Bromelain was isolated from pineapple peels using different techniques and isolated bromelain to be used in the treatment of fabrics was encapsulated. Encapsulation was preferred to increase enzyme stability and reusability and to reduce cost. Area shrinkage, pilling, tensile strength, elongation, and weight loss tests were performed on the treated fabrics. According to the findings of this study, the isolated and encapsulated bromelain from pineapple peel wastes improved the washability of the wool fabric and eliminated the pilling problem. This developed method is sustainable, low cost, high added value, innovative, and environmentally friendly.
Nurses Knowledge and Associated Factors towards Hemodialysis Care at Governmental Dialysis Units in Addis Ababa, Ethiopia
Authors: Fanta Amanuel , Legesse Temesgen , Legesse Tamrat
Published: May 2023

Hemodialysis is a process of purifying the blood of a person whose kidney is not working normally. Little is known about the nurses’ knowledge and associated factors while caring for patients undergoing hemodialysis. The aim of this study was to evaluate knowledge and associated factors of hemodialysis among nurses. Methods: Institution based cross-sectional survey design was conducted among dialysis care provider nurses. A total of 62 nurses giving hemodialysis care were included. Data were analyzed using SPSS version 26.0 software in logistic regression model. Descriptive statistics were expressed as percentage and frequency. Adjusted odds ratio with 95% confidence interval was used to measure factors associated with the outcome variable considering P < 0.05 to declare statistical significance. Result: Among the 62 nurses enrolled, about 70% were knowledgeable regarding hemodialysis. Nurses experience in working dialysis [AOR: 10.18 95% CI: 2.18, 47.40)], training of nurses (AOR = 5 95% CI: 1.12–22.20) were significantly associated with the knowledge of nurses regarding hemodialysis care. Conclusion: In this study we found that nurses experience working in hemodialysis and years of work experience were factors affecting their knowledge towards hemodialysis service. Thus, interventions should focus on improving experience and training of nurses regarding hemodialysis care to improve the compressive knowledge of nurses.
Fuzzy PID Control of Electric Vehicle Charging and Discharging System
Authors: Li Jianwei
Published: May 2023

The speed regulation and stability control performance, mileage and battery life of new energy vehicles have an important impact on the development of electric vehicles. In order to analyze the impact of different discharge control strategies on the speed regulation, battery output voltage and capacity of electric vehicles, the battery discharge model is built by using MATLAB software. By simulating the starting, speed regulation and load changes of electric vehicles, it corresponds to three situations: constant speed starting, sudden change of speed during operation and sudden load, The traditional proportional integral differential controller (PID) and fuzzy PID control strategies are used to simulate and analyze the battery discharge. The results show that the control effect and accuracy of fuzzy PID controller on motor speed, speed regulation response speed and voltage output are better than those of traditional PID controller, which verifies the rationality and stability of the proposed fuzzy PID vector control.
Identification of six genes associated with COVID-19-related Circadian rhythm dysfunction by integrated bioinformatic analysis
Authors: Xu Yanfeng , Zhang Mingyu , Wang Guanyun , Yang Jigang
Published: May 2023

Background Patients with coronavirus disease 2019 (COVID-19) might cause long-term burden of insomnia, while the common pathogenic mechanisms are not elucidated.Methods The gene expression profiles of COVID-19 patients and healthy controls were retrieved from the GEO database, while gene set related with circadian rhythm were obtained from Genecards database. The weight gene co-expression network analysis (WGCNA) algorithms were conducted to identify the most correlated gene module with COVID-19. Functional enrichment analysis and protein-protein interaction network (PPI) were performed on shared genes between key module and circadian rhythm gene set. Hub genes were identified and gene regulatory networks, immune cell Infiltration evaluation and Drug–Gene interaction were constructed.Results 76 shared genes were screened and mainly enriched in cell cycle, cell division and cell proliferation, and 6 hub genes were found out including CCNA2, CCNB1, CDK1, CHEK1, MKI67 and TOP2A, with positive correlation to plasma cells. In the TF-gene regulatory network, NFYA, NFIC, MEF2A and FOXC1 showed high connectivity with hub genes.Conclusions This study established the co-expression network and identified six hub genes, which might provide new insights into pathogenic mechanisms and novel clinical management strategies.
Cost Benefit Analysis of Alternative Coffee Drying Methods at Limmu Kossa and Gomma I of Horizon Coffee Plantation PLC
Authors: Eshetu Elfinesh Firdissa , Huluka Admassu Tesso
Published: May 2023

Around 40% of coffee quality is determined in the field, with the remaining 60% determined by post-harvest processing procedures. This demonstrates the significance of coffee processing in improving quality and value. As a result, this article examines the economic viability of Horizon Coffee Plantation Farm's three coffee drying methods: solar tunnel dryer, artificial dryer, and sun dryer. Several economic viability assessments and cost-benefit analyses are used. Furthermore, for each strategy, switching values and sensitivity analysis were done. According to the findings, the gross margin rate for the solar tunnel is Birr 35 per kg of green, followed by Birr 34.75 for the artificial drier machine and Birr 34.2 for the sun dryer method. Similarly, the artificial dryer method was found to be the most viable, with the highest NPV of Birr 89,292,673, followed by Birr 10,016,909 for the solar tunnel method and Birr 175,295 for the sun dryer method, implying that the firm's methods are all economically viable. The BCR and IRR criteria also confirm the same conclusion. The viability of all drying methods remains nearly constant regardless of the potential in costs of production and sales prices. Because investments in all drying methods are non-mutually exclusive, it is advised that the corporation continue to invest in all three drying methods as long as their NPV is greater than zero. However, this finding should be interpreted with caution because the present rise in fuel prices may make the use of artificial dryer methods more expensive and unviable.
Anti-proliferative effect of leaf phytochemicals of soursop (Annona muricata L.) against human osteosarcoma in vitro
Authors: Shanmugam Haripriya , Narmadha R. , Ravikumar Caroline , Ariyaperumal Kiruthika , Selvakumar R. , Mannu Jayakanthan
Published: May 2023

Soursop (Annona muricata) is being used in treating various types of cancers and there is no report on effect of soursop leaf phytochemicals against osteosarcoma. Current study identified 28 metabolites from ethyl acetate leaf (EAL) extract through GC-MS chemoprofiling and subjected to in silico analysis against the potential protein target, Platelet Derived Growth Factor Receptor α (PDGFRA) of osteosarcoma, including Absorption, Distribution, Metabolism, and Excretion and Toxicity (ADMET) analysis to identify possible hit compounds. This resulted in three hit leaf bioactives namely, 2’- hydroxy-5’-methyl chalcone, linoleic acid and annonacin showing good binding affinity with a docking score of -7.4, -7.0 and – 6.9 kcal/mol respectively. With ADMET analysis, 2’- hydroxy-5’-methyl chalcone and linoleic acid obeyed Lipkinsi’s rule of five, whereas annonacin showed slight violation. Among the three docked complexes, annonacin exhibited good stability during molecular dynamic simulation performed with PDGFRA. Hence, concentration of the key marker compound, annonacin in EAL concentrate is found to be 5.032± 0.13 mg/g of leaf sample. Further, EAL concentrate exhibited cytotoxicity (IC50 value) on MG-63 osteosarcoma cells in vitro for concentrations ranging from 10 to 25 µg/mL and nuclear imaging of osteoblast cells treated with EAL concentrate at 25 µg/mL concentration exhibited typical symptoms of apoptosis. In vitro cytotoxicity along with nuclear imaging confirmed EAL concentrate from soursop to be a potential drug candidate in developing new anti-cancer agent against osteosarcoma.
A new method for researching terramechanics problems of underwater tracked vehicles
Authors: Huang Weijian
Published: May 2023

In the process of mining the seabed resources, underwater tracked vehicles (UTVs) penetrate and shear the seabed during walking. Traditionally, the bevameter technique is widely chosen to research the above processes. However, the bevameter technique does not reflect the track-soil interaction, which includes ignoring the grousers’ effect in the penetration process and the connection between these two processes. In order to better simulate the track-soil interaction, here, a new method is proposed based on the torsional penetrometer that can integrate the penetration process and the shearing process into a continuous simulation, while the grousers’ effect is reflected. Furthermore, the corresponding formulas of key driving indicators are derived. To verify the validity of the new method, a set of comparative tests were carried out. The results indicated that the peak pressure of the new method was 20% bigger than those of the traditional method due to the consideration of the grousers’ effect, the peak shear stress and residual stress of the new method were respectively 33% and 30% bigger due to the continuous simulation, all of which showed the new method’s reliability and applicability.
Bilateral subcutaneous fatty flaps (BSF) for the treatment of recurrent pilonidal sinuses are a Novel technique superior to Z-plastics (ZP)
Authors: Saad Hassan A , Eraky Mohamed E , Elsayed Ashraf abdelmonem , Riad Mohamed , El-Taher Ahmed K , Elsayed Rasha S
Published: May 2023

Background:
Pilonidal disease has numerous management techniques available to surgeons worldwide. Because of the variety of clinical manifestations, several methods of intervention are needed; as a result, we hope for careful selection of the best technique for the patient's severity and recurrence.
Aim: To prevent possible recurrence after bilateral subcutaneous fatty flap(BSF), a novel method for treating pilonidal sinus illness and Z-Plasty(ZP) with fasciocutaneous flap.
Patients and methods:
All prospective patients having recurrent pilonidal sinus and operated on at our institute, Surgical Department from Jan. 2022 to Dec. 2023. In total, 50 cases have sacrococcygeal disease ( SCD), and 25 patients in Group A had bilateral subcutaneous fatty flap surgery. In contrast, the 25 patients in Group B were treated by Z-Plasty(ZP) with fasciocutaneous flap surgery. We assessed the length of the procedure, the level of postoperative pain, the length of the hospital stay, the postoperative complications, and the likelihood of recurrence.
Results:
The wound size was in the bilateral Subcutaneous fatty flap (BSF) 28.11 ± 8.48 mm relative to the (ZP) 23.84 ± 8.44 mm). Also, the complete healing was comparatively prolonged in the BSF (13days) relative to the ZP group (30 days). The surgery duration differs significantly (P < 0.001) between the groups; it was lower in the BSF group (29.15 ± 7.69 mins) than in the ZP (23.03 ± 6.06 mins). In the BSF group, the hospitalization was four days. Still, ZP group (11days), The time for work recovery or activity was shorter in the BSF (11 days) relative to the ZP group (36 days). BSF had more reasonable satisfaction than the ZP group, duration of wound healing in BSF being 11 days but in ZP 30 days. Additionally, the duration of pain in the group was ZP (38 days but in the BSF group (11 days).
Return to work in BSF 11 days and in ZP 36 days; The median satisfaction scores attained 8 (28.1%) in BSF and 9 (37%) in the ZP (P = 0.046). The median VAS scores attained 37.8% BSF and 44% for ZP (P = 0.934). The highest VAS score was equal to group B, which was 6.
Conclusion:
when treating pilonidal sinus disease, the bilateral subcutaneous fatty flap is superior to the ZP flap.
Effect of Manual Reduction Combined with Internal Fixation Through Wiltse Paraspinal Approach in the Treatment of Thoracolumbar Fracture (AO type A3)
Authors: Li Yang , Wu Ji , Gao Zhongya , Qiu Youcai , Zhang Jianjun , Yang Haisong , Lu Xuhua
Published: May 2023

Background: Thoracolumbar fractures (TF) are the most frequent fractures of the spine, and the current treatment for TF (AO Type A3) is the Wiltse approach with pedicle screw fixation or percutaneous pedicle screw fixation. However, secondary collapse often occurs after operation. To reduce the incidence of such events, preoperative manual reduction (MR) is an efficient method. The purpose of this study is to investigate the impact of successful PMR on prognosis of patients with TF.
Methods: From 2018 to 2022, 97 patients are enrolled to the study. Patients are divided into three groups, MR failure (MRF), succeeded (MRS) and instrument reduction (IR). The different time of the Cobb angel (CA) and vertebral body height ratio (VBHR) are obtained for three groups. The visual analog scale (VAS) is used to help patients assess the intensity of their pain, and oswestry disability index (ODI) is regarded as the gold standard for evaluating the degree of dysfunction caused by TF.
Results: The recovery of CA and VBHR, MRS and IR is significantly better than MRF at 2 days and 6 months after operation. The CA and VBHR are found to be different between preoperative and 2 days, 6 months after operation. The CA and VBHR in MRF are decreased at 6 months after surgery compared with 2 days after surgery. In the results of VBHR 6 months after operation, there is significant difference between MRS and IR.
Conclusion:
Successful preoperative manual reduction can greatly improve and maintain vertebral height and spinal physiological curvature. In addition, according to the success of manual reduction, TF of AO Type A3 can be divided into A3a and A3b.
Identification of anti-inflammatory mechanism of action and molecular targets of Hypericum perforatum in the treatment of major depression based on bioinformatics methods and machine learning
Authors: Xu Zewen
Published: May 2023

Background
Major depressive disorder (MDD) is one of the most common psychiatric disorders worldwide. The diagnosis and treatment of MDD is a major clinical issue. Hypericum perforatum (HP) is a traditional herb that has been shown to have antidepressant effects, but its mechanism is unclear. This study combined bioinformatics approach and molecular docking prediction to identify the mechanism of action and molecular targets of HP for the treatment of MDD from the perspective of signaling pathways and immune inflammation.
Methods
We performed differential analysis and weighted gene co-expression network analysis (WGCNA) with the GSE98793 depression expression dataset to intersect the identified DEGs and significant module genes to obtain intersection genes. Three databases, CTD, DisGeNET and GeneCards, were used to retrieve MDD-related gene intersections to obtain MDD predicted targets. The validated targets were retrieved from the TCMSP database. The enriched pathways were analyzed separately to obtain KEGGa, KEGGb and KEGGc. 13 key pathways were obtained by combining them. The PPI network was constructed by extracting the intersection of genes and HP validated targets on all key pathways. Five key therapeutic targets (AKT1, MAPK1, MYC, EGF, HSP90AA1) were obtained using MCODE and machine learning (LASSO, SVM-REF). Clinical diagnostic assessments (Nomogram, ROC, Correlation, Intergroup expression), gene set enrichment analysis (GSEA) were performed for the 5 key targets. In addition, immuno-infiltration analysis was performed on the MDD dataset to explore the regulatory mechanisms of the 5 key targets. Finally, molecular docking prediction was performed for the targets of HP active ingredients on MDD.
Results
Differential expression analysis and WGCNA module analysis yielded 933 potential targets for MDD. Three disease databases were intersected to 982 MDD predicted targets. The TCMSP retrieved 275 valid targets for HP. Separate enrichment analysis intersected to 13 key pathways. Five key targets (AKT1, MAPK1, MYC, EGF, HSP90AA1) were finally screened based on all enriched genes and HP valid targets. Combined with the signaling pathway and immune infiltration analysis, the effect of peripheral immunity on MDD and the important role of neutrophils in immune inflammation were investigated. Finally, the binding of HP active ingredients (quercetin, kaempferol and luteolin) and all 5 key targets was predicted based on molecular docking.
Conclusions
The active constituents (quercetin, kaempferol and luteolin) of Hypericum perforatum may act on MDD and its inflammatory symptoms through key targets (AKT1, MAPK1, MYC, EGF, HSP90AA1) and pathways such as neutrophil extracellular trap formation.
Innovation in education for quality of care: a scoping review
Authors: Sa Juliana , Zapata Tomas , Muscat Natasha Azzopardi , Breda Joao , Martins Henrique
Published: May 2023

Background:
Ensuring quality-of-care and promoting patient safety is a core competence that healthcare professionals are called to develop. Healthcare contexts are continuously changing advancing with social and technical innovations. The aim of this review is to identify innovative approaches in educational activities on quality of care, quality improvement and education about innovation for health professionals. Seeking evidence about educational strategies that are innovative or target innovation while addressing quality-of-care and quality improvement.
Methods:
A scoping review has been conducted searching for papers published between January 2000 and September 2022. Data bases used were PubMed, APA PsycInfo, SCOPUS, Web of Science and CINAHL using the terms “quality improvement”, “quality of care”, “education”, “teaching”, “innovation” and “healthcare”. Papers included characterized the state of quality training and described interventions on quality education in undergraduate and postgraduate training of healthcare professionals.
Results:
From the 2059 papers found, 11 were included in the study. Authors were mainly from USA and UK; most studies were about undergraduate training. Most interventions described the inclusion of Quality Improvement in the curricula. Papers were analyzed using a proposed innovation lens and classified accordingly. Seven papers were considered as Routine Innovations, one as (potentially) Disruptive, two as Radical and none as Architectural.
Conclusions:
There is a paucity of evidence on innovative educational approaches or education about innovation for quality-of-care, with few studies targeting quality improvement only. Most of the interventions were considered routine innovation. There is an urgent need to include quality-of-care training in undergraduate curricula and doing so in innovative ways; a model to advance this is presented.
Systematic study of the dynamics of liquid capillary rise within vertical microchannels
Authors: Sánchez-García Rubén E. , Castilleja-Escobedo Orlando , García-Cuéllar Alejandro , López-Salinas José L.
Published: May 2023

The study of capillary rise of different fluids in a capillary tube is analyzed using different experimental and mathematical methods and simulation with Computational Fluids Dynamics (CFD). Experimental tests are carried out, which in turn are compared with simplified mathematical models and CFD simulations trying to predict the same behavior of the experiments, discussing the similarities or differences found. Capillary forces or linear forces are assumed to have a significant impact on the process by neglecting gravitational forces. We find that for certain cases (depending on the time scale) the behavior can be favorable. Just as the properties of viscosity, interfacial tension and contact angle predominate in the behavior of fluids in the simulations, even the type of tube material also influences the behavior. Since if the material is hydrophilic or hydrophobic it drastically changes the conduction of the fluid, allowing you to be able to predict properties on site.
Epidemiological Patterns of Acute Type-A Aortic Dissection in Regional New South Wales - A 10-year Analysis
Authors: Rathnayake Ayeshmanthe , Chang Olivia , Narita Takuya , Mejia Rosauro
Published: May 2023

Background:
Acute Aortic Dissection (AD) is a surgical emergency with significant mortality without prompt diagnosis and operative intervention. The management is time critical and regional Australia represents an area of interest owing to its large distances and often paucity of resources. No previous studies examining Type-A AD in regional Australia have been done. The aim of this study is to illustrate the epidemiological trends in Type-A AD within a regional population of Australia. The primary outcomes are prevalence and mortality. The secondary outcomes are assessment of risk factors, challenges in diagnosis and associated complications.
Methods:
A retrospective analysis was undertaken in the Hunter New England (HNE) health district of New South Wales (NSW), Australia. We retrospectively examined data from 2010 to 2020 in the population of the Hunter New England health district. The data was analysed using Microsoft Excel and Statistical Package for Social Sciences (SPSS).
Results:
The prevalence of Type-A AD in the HNE was 1.47 per 100,000 and mortality was 2.12 per 100,000 which was lower compared to previous studies. Five percent of patients identified as Aboriginal and Torres Strait Islander. Combined risk factors of smoking and hypertension, postoperative CVA and misdiagnosis demonstrated higher mortality which were statistically significant (p < 0.05).
Conclusion:
This study is the first study to illustrate Type-A AD in regional Australia. The epidemiological trends, analysis and risk factor profiles present a solid foundation for future prospective studies to be based on to ultimately allow better patient outcomes.
Detecting Exoplanets in Multiplanetary Systems using HI Line Analysis through Gaussian Fitting
Authors: Dutta Pritam , Saraswat Rushil
Published: May 2023

The paper describes the detection of exoplanets in multiplanetary systems using HI line data is an approach in astronomy. Traditional methods for detecting exoplanets have limitations in terms of sensitivity and range, which makes it difficult to detect small and distant planets. We propose a mathematical model based on the analysis of the HI line emission and absorption spectra to predict the presence of exoplanets.The model is based on fitting the observed HI line profile to a Gaussian distribution f(v) = Aexp[−(v − vθ) 2 /(2δv2 )] + δf(v) where δf(v) is the perturbation caused by the exoplanet. The amplitude of the perturbation depends on the mass, orbital distance, and other properties of the exoplanet. and searching for significant deviations that may indicate the presence of an exoplanet.The chi-squared statistic,x 2 , measures the difference between the observed and expected HI line profiles: x 2 = P∞ n=1 2 −n = 1[fobs(v) − fexp(v)]2 /σ2 . The deviation caused by the exoplanet can be quantified using a perturbation term in the 19 Gaussian distribution. The amplitude of the perturbation depends on the mass, orbital distance, and other properties. We use statistical tests such as the chi-squared test to measure the significance of the deviation and estimate the properties of the exoplanet and the Extragalactic distance scale.