bluuebunny/crossref_metadata_2025 huggingface dataset:
The principles of tomorrow's university
Authors: Katz Daniel S. , Allen Gabrielle , Barba Lorena A. , Berg Devin R. , Bik Holly , Boettiger Carl , Borgman Christine L. , Brown C. Titus , Buck Stuart , Burd Randy , de Waard Anita , Eve Martin Paul , Granger Brian E. , Greenberg Josh , Howe Adina , Howe Bill , Khanna May , Killeen Timothy L. , Mayernik Matthew , McKiernan Erin , Mentzel Chris , Merchant Nirav , Niemeyer Kyle E. , Noren Laura , Nusser Sarah M. , Reed Daniel A. , Seidel Edward , Smith MacKenzie , Spies Jeffrey R. , Turk Matt , Van Horn John D. , Walsh Jay
Published: December 2018

In the 21st Century, research is increasingly data- and computation-driven. Researchers, funders, and the larger community today emphasize the traits of openness and reproducibility. In March 2017, 13 mostly early-career research leaders who are building their careers around these traits came together with ten university leaders (presidents, vice presidents, and vice provosts), representatives from four funding agencies, and eleven organizers and other stakeholders in an NIH- and NSF-funded one-day, invitation-only workshop titled "Imagining Tomorrow's University." Workshop attendees were charged with launching a new dialog around open research – the current status, opportunities for advancement, and challenges that limit sharing.

The workshop examined how the internet-enabled research world has changed, and how universities need to change to adapt commensurately, aiming to understand how universities can and should make themselves competitive and attract the best students, staff, and faculty in this new world. During the workshop, the participants re-imagined scholarship, education, and institutions for an open, networked era, to uncover new opportunities for universities to create value and serve society. They expressed the results of these deliberations as a set of 22 principles of tomorrow's university across six areas: credit and attribution, communities, outreach and engagement, education, preservation and reproducibility, and technologies.

Activities that follow on from workshop results take one of three forms. First, since the workshop, a number of workshop authors have further developed and published their white papers to make their reflections and recommendations more concrete. These authors are also conducting efforts to implement these ideas, and to make changes in the university system.  Second, we plan to organise a follow-up workshop that focuses on how these principles could be implemented. Third, we believe that the outcomes of this workshop support and are connected with recent theoretical work on the position and future of open knowledge institutions.
Modern Trends in the Breast Cancer Conserving Surgery and Oncoplastic Breast Surgery
Authors: Зикиряходжаев А. , Zikiryahodjaev A. , Ермощенкова М. , Ermoshchenkova M. , Каприн А. , Kaprin A. , Чиссов В. , Chissov V. , Запиров М. , Zapirov M.
Published: December 2018

Introduction: The highest priority for modern clinical oncology is functionally-sparing and organ-conserving treatment. In Russia, breast cancer (BC), among all malignant tumors, accounted for 21.1 % of women in 2017. Oncoplastic radical resections (OPS-BCS = oncoplastic surgery – breast conserving surgery) have been widely used. This term means resection of the breast for cancer using plastic surgery to restore the shape of the breast, in most cases with one-stage correction of the contralateral breast. Purpose: It was the creation of various techniques of oncoplastic breast surgery, applicable for the appropriate localization of breast cancer and the evaluation of surgical, oncological and aesthetic results. Methods: From 2013 to 2017, in the P.A. Hertsen Moscow Oncology Research Center, organ-conserving surgery were performed in 570 patients with BC with an average age of 54.2. Stage 0 was diagnosed in 4.6 %, I – 5.9 %, IIA – 28.7 %, IIB – 6 %, IIIA – 5.1 %, IIIC – 3.3 %, IIIB – 0.2 %, IV – 0.2 %. Radical resection in the standard version was performed in 290 patients with breast cancer, oncoplastic breast surgery in various modifications – in 280. All patients after the organ-conserving surgical treatment received radiation therapy. Patients received chemotherapy, targeted therapy and hormone therapy according to the indications in depending the disease stage and the immunohistochemical type of the tumor. Results: After an urgent and planned morphological study positive margins of resection were revealed in 10 patients, which required reresection of the edges to a negative state of them in case of an urgent intraoperative response and mastectomy – in case of a planned response. Within 4 years, local recurrences were detected in 4 patients (0.7 %), which required a mastectomy with a one-stage reconstruction. In 1 patient (0.2 %), the disease progressed as metastases to the lung – in this case lobectomy and a necessary chemotherapy were conducted. Cosmetic results were defined as excellent in 70 % cases, good – 25 %, satisfactory – 5 %. Conclusion: If there are indications for organ-conserving treatment of breast cancer and the patient’s decision concerning this surgery, the patient should be offered methods of oncoplastic surgery for the prevention of psychological and emotional stress, effective rehabilitation, and a quick return to active social life.
UM PERSONAGEM, DOIS MUNDOS: ISAÍAS CAMINHA EM 1909 E EM 2014
Authors: Calegari Lizandro Carlos , Amaral-Oliveira Anderson
Published: December 2018

ResumoEste artigo de cunho literário-comparativo apresenta a investigação aspectos inerentes à construção do narrador Isaías Caminha em duas obras literárias intimamente relacionadas: Recordações do escrivão Isaías Caminha, de Lima Barreto, publicada pela primeira vez em 1909 e A lição de anatomia do temível Doutor Louison, de Enéias Tavares publicada em 2014. Como metodologia de pesquisa, foi realizada uma análise estrutural das obras, empregando teorias da narratologia como forma de evidenciar aspectos constitutivos de ambas as narrativas, do narrador e personagem. O resultado da análise afirma que a multiplicidade discursiva foi o mecanismo encontrado pelo romancista contemporâneo para possibilitar significações em diferentes níveis diegéticos, diferentemente da obra fonte. Conclui-se que tal relações intertextuais, permite reabrir diversos diálogos com a história, com o presente e o com futuro da nossa cultura, que encontra em si mesma recursos e motivação para criar novas formas de expressão aproximando séculos de conhecimento acumulado e desafiando novos escritores e leitores.
A PRIMEIRA UCRONIA BRASILEIRA: A CASCA DA SERPENTE E A RETIFICAÇÃO DO MUNDO
Authors: Chaves Jayme Soares
Published: December 2018

Este trabalho tem como objetivo contextualizar o romance A casca da serpente, de José J. Veiga, no panorama geral dos subgêneros literários conhecidos como “história alternativa” (ou “ucronia ficcional”) e “ficção recursiva”, ou crossover. Justifica-se o intento não apenas por este romance ser considerado o primeiro exemplo de história alternativa na literatura brasileira, como também pelo fato de ser possível dividi-lo em duas partes bastante distintas, sendo a primeira história alternativa stricto sensue a segunda um exemplo, ainda que problemático, de “ficção recursiva”. Por outro lado, o romance não se esgota nestas duas categorias, mas se vale delas para a construção e o reforço de um mito histórico e político, como tentaremos demonstrar.
BREVES NOTAS SOBRE A FICÇÃO FOLCLÓRICA NO BRASIL
Authors: Costa Andriolli De Brites
Published: December 2018

Este artigo busca primeiramente estabelecer uma demarcação acadêmica para a ficção folclórica enquanto subgênero da ficção especulativa, distinguindo-a meramente de uma literatura regionalista ou de outras tentativas de nomenclatura contemporâneas. Traz ainda reflexões e apontamentos para delinear as potencialidades e desafios com os quais esta se depara na cena nacional de literatura fantástica. Para tanto, iniciamos explorando e problematizando o conceito de folclore, e em seguida construímos as aproximações entre a literatura fantástica brasileira e os temas da cultura popular desde o Romantismo do século XIX e seus ímpetos de valoração da tradição até o Fantasismo contemporâneo, no qual os mitos e lendas servirão de mote para desbravar esse Brasil fantástico ainda tão pouco explorado.
FANTASIA MATERIALISTA EM ORDEM VERMELHA: FILHOS DA DEGRADAÇÃO
Authors: Amaral George Augusto do
Published: December 2018

Neste artigo busco analisar o romance Ordem Vermelha: Filhos da Degradação a partir de uma perspectiva da crítica materialista, defendendo que, tanto em relação à forma quanto ao conteúdo, a obra rompe com as características de uma Fantasia literária clássica, aproximando-se do que Fredric Jameson classifica como Fantasia Materialista. Além disso, abordo a maneira com que o romance se encaixa no pressuposto de um tipo de arte de cunho político e pedagógico produzida em um contexto pós-moderno, no qual questões espaciais se sobrepõem às temporais, traçando um mapeamento cognitivo da realidade pelo viés do fantástico. Por fim, busco refletir a respeito do tema das metanarrativas, tema elaborado dentro da história do romance, mostrando que o autor não desqualifica a validade dessas narrativas mestras, mas reflete e alerta a respeito da importância da consciência social para que seja possível perceber as contradições e ideologias que nos cercam.
ENTREVISTA COM O ESCRITOR ERIC NOVELLO
Authors: Matangrano Bruno Anselmi
Published: December 2018

RECEBIDO EM 18 OUT 2018APROVADO EM 28 OUT 2018
Új generáció és régi szerepek egy krónikás szemével
Authors: Bognár László
Published: December 2018

Between 1377 and 1382, not more than in a five year period, series of kings – partly in parallel with them, partly following them – and a remarkable part of the social elite were replaced in the area of Western Europe. This essay focuses on the English changes through the Chronicle of Thomas Walsingham entirely from the death of the Black Prince until the enthronement of Henry IV. Several components can be considered as reasons for the weakening royal power in the age of Richard II: his uncles’ influence, the king’s personal age and the unsolved social issues all contributed to the decrease of the royal authority. Nevertheless, examining the chronological tables a sharp change in the European generations is noticeable, until the midst of 1380s Walsingham mainly focuses on the religious differences and the effects of the generation change only appears at a higher rate from the second half of the decade. Many times – basing on the text of the chronicle – the historian personal point of view appears; in certain descriptions it is externalized to the whole aristocracy to contrast them with the reigning social elite of Edward III’s generation.
"Senkit sem hagyunk hátra!"
Authors: Lengyel Ádám
Published: December 2018

In my study I compare two of the many combat rescue missions from the recent history. These two operations are the Battle of Mogadishu on 3–4. October 1993., and the Battle of Takur Ghar on 4–5. March, 2002. I will examine the physical and political environments, the operational plans, the American and the opposition forces involved in the missions, the exact events that lead to combat rescue missions, and the aftermaths of the two battles.
A holokauszt oktatása Kelet-Közép-Európában, középiskolában használatos tankönyvek tükrében
Authors: Jancsák Csaba , Képíró Ágnes , Kiss Mária Rita , Kontár Piroska , Szőnyi Andrea
Published: December 2018

The criteria of and research approaches to textbook analysis are manifold and diversified. The present study is based on the methodological foundations of comparative textbook analysis as it is typologized by Wiater (2003), and it focuses on one specific segment (the Holocaust), examining how oral history, personal narratives and relevant digital online content appear in teaching history. Our paper presents a microlevel analysis, specifically addressing textbook content, an approach fundamentally rooted in educational sociology. Our main questions focus on how textbooks used in Central Eastern Europe (Poland, Hungary, Serbia, Slovakia and Ukraine) support history teaching with respect to civic education and subject specific value transfer, and what congruence there is regarding video content available through ICT and the new challenges of teaching the screenager generation.
Blood parameters and productivity of broilers fed ration composed of microparticle protein with the addition of Lactobacillus sp.
Authors: Wulandari L.T. , Suthama N. , Sukamto B.
Published: December 2018

The study was aimed to evaluate the effectiveness of feeding dietary microparticles protein added with Lactobacillus sp. on blood parameters and broiler productivity. A total of 192 birds of 21 days old broiler with initial body weight of 481 ± 67 g were divided into 8 treatments and 4 replications (6 birds each) of a completely randomized design (CRD). Dietary treatments were T0: 21% intact protein ration, T1: 18% intact protein ration, T2: 21% microparticle protein ration, T3: 18% microparticle protein ration, T4: T0 + 1.2 mL Lactobacillus sp, T5: T1 + 1.2 mL Lactobacillus sp., T6: T2 + 1.2 mL Lactobacillus sp., and T7: T3 + 1.2 mL Lactobacillus sp. Parameters observed were total lactic acid bacteria and Coliform, pH, blood cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), meat cholesterol, meat weight, feed consumption, and body weight gain (BWG). Data were analyzed using analysis of variance and followed by Duncan test (P<0.05). The results showed that T7 treatment significantly (P<0.05) decreased blood cholesterol, LDL, and meat cholesterol, but increased HDL, meat weight, and BWG. Blood cholesterol, LDL, and meat cholesterol were indicated significantly (P<0.05) lowest values due to T7 treatment. In conclusion, feeding 18% microparticle protein with addition of 1.2 mL Lactobacillus sp. can improves blood status and increases broiler productivity.
Estrus and pregnancy rate of Simmental-Ongole Crossbred and Ongole Grade heifer after being synchronized and inseminated
Authors: Sutiyono S. , Samsudewa D. , Suryawijaya A.
Published: December 2018

The aim of the study was to examine the synchronization of estrus and artificial insemination in heifers of Ongole grade and Simental-Ongole grade. The research used 19 Ongole Grade (OG) and 18 Simental-Ongole Crossbred (SOC) heifers. This research applied purposive sampling to determine the research population. The criteria to select the population were heifers which have in mature body. The normality of heifer’s reproductive organs were identified by performing rectal palpation, then 50 mg of medroxy progesterone acetate on vaginal sponge was used to synchronized estrus. The estrus heifer was inseminated using frozen semen. The observed parameters were the number of heifers with normal and abnormal reproductive organs, estrus sign and pregnancy. Data were analyzed descriptively. This study showed that OG and SOC with abnormal reproductive organs was 1 heifer (5.56%) and 7 heifers (36.84%), respectively. The responses of estrus synchronization in heifers with normal and abnormal reproductive organs were 94.17% and 100% in OG, and 100% and 42.86% in SOC. Meanwhile, the pregnancy rate was 70.59 and 0% in OG, and 50.00 and 0% in SOC. In conclusion, the number of SOC heifers with abnormal reproductive organs is higher than OG. Estrus synchronization using 50 mg medroxy progesterone acetate increase the amount of estrus and pregnancy in heifers with normal reproductive organs.
Ancient China reconsidered
Authors: Fiskesjö Magnus
Published: December 2018

These three ambitious, successful and highly rewarding books help us to rethink the archaeology of ancient China and its context. The work co-authored by Linduff, Sun, Cao and Liu is the most wide-ranging. It offers an overview of ancient Chinese interactions with Central Asian neighbours over more than two millennia, from the first beginnings of metal use up to the Iron Age. It also aims to change the narrative of this region by re-interpreting the ‘Inner Asian frontier’ as a multi-centred, dynamic, diverse and changing ‘contact zone’ unlike the uniform barbarian steppe set apart from incipient Chinese civilization that an earlier literature tended to imagine. The authors focus on distinct yet overlapping aspects of life and interaction on this frontier—‘technoscapes’, ‘individualscapes’, ‘lineagescapes’, ‘regionscapes’—departing from the Sinocentric view where the only interesting questions about ancient frontier peoples were how the barbarians contributed (or not), to the making of the (glory of the) Sino-centres. The recent exciting debates over the Shimao “city too far north” (Jaang et al. 2018) come to mind!
Atrial Fibrillation and Exercise: Exercise Recommendations
Authors: Sorace Paul , Ronai Peter , Berry Robert
Published: December 2018

ATRIAL FIBRILLATION (AF) IS CHARACTERIZED BY A RAPID PULSE RATE AND AN IRREGULAR HEART RHYTHM. IT IS A MORE COMMON CARDIAC ARRHYTHMIA. AF MAY LACK SYMPTOMS, ALTHOUGH FATIGUE AND AN IMPAIRED EXERCISE ABILITY ARE COMMON SYMPTOMS. THIS COLUMN WILL DISCUSS EXERCISE TESTING AND TRAINING RECOMMENDATIONS AS WELL AS SPECIAL CONSIDERATIONS.
Between Myths, Memories, History, and Politics
Authors: Dekel-Chen Jonathan
Published: December 2018

This essay aims to share with the readers of The Public Historian some of the challenges, thoughts, and conclusions that I encountered as a historian during the planning and execution of content for the Jewish Museum and Tolerance Center in Moscow. As the essay illustrates, this extraordinary project sat at the intersection of a troubled history, widely divergent popular memories and national narratives, and divisive contemporary politics. The essay’s possible uses are twofold: first, it offers insight for professionals into the intricacies of creating a large-scale, historically accurate museum in a complex political environment in today’s Russia; second, it may help give some guidance to historians who find themselves in similar scenarios.
Autoimmune hypoglycaemia caused by alpha-lipoic acid: a rare condition in Caucasian patients
Authors: Veltroni A , Zambon G , Cingarlini S , Davì M V
Published: December 2018

Insulin autoimmune syndrome (IAS), a rare cause of autoimmune hyperinsulinaemic hypoglycaemia, is relatively well known in Japan. The incidence in Caucasians is less than one-fifth of that reported in Japanese people, but it is becoming increasingly recognised worldwide in non-Asians as well. Drugs containing sulphydryl groups are known to be associated with the disease in genetically predisposed individuals. Moreover, several recent reports showed a direct association between the onset of IAS and the consumption of dietary supplements containing alpha-lipoic acid (LA). Insulinoma remains the most prevalent cause of hypersulinaemic hypoglycaemia in Caucasians. Consequently, primary investigation in these patients is generally focused on localisation of the pancreatic tumour, often with invasive procedures followed by surgery. We described a case of an Italian woman presenting to us with severe recurrent hypoglycaemia associated with high insulin and C-peptide levels and no evidence of pancreatic lesions at imaging diagnostic procedures. She had taken LA until 2 weeks before hospitalisation. After an evaluation of her drug history, an autoimmune form of hypoglycaemia was suspected and the titre of insulin autoantibodies was found to be markedly elevated. This allowed us to diagnose LA-related IAS, thus preventing any unnecessary surgery and avoiding invasive diagnostic interventions.

Learning points:

IAS is a rare cause of hyperinsulinaemic hypoglycaemia that typically affects Asian population, but it has been increasingly recognised in Caucasian patients.

It should be considered among the differential diagnosis of hyperinsulinaemic hypoglycaemia to avoid unnecessary diagnostic investigations and surgery.

It should be suspected in the presence of very high serum insulin levels (100–10  000  μU/mL) associated with high C-peptide levels.

There is a strong association with administration of drugs containing sulphydryl groups included LA, a dietary supplement commonly used in Western countries to treat peripheral neuropathy.
MECHANISMS OF ENDOCRINOLOGY: Mechanisms of disease: the endocrinology of obstructive sleep apnoea
Authors: Lavrentaki Aikaterini , Ali Asad , Cooper Brendan G , Tahrani Abd A
Published: December 2018

Obstructive sleep apnoea (OSA) is a common disorder that is associated with serious comorbidities with a negative impact on quality of life, life expectancy and health costs. As OSA is related to obesity and is associated with sleep disruption, increased inflammation and oxidative stress, it is not surprising that OSA has an impact on the secretion of multiple hormones and is implicated in the development of many endocrine conditions. On the other hand, many endocrine conditions that can affect obesity and/or upper airways anatomy and stability have been implicated in the development or worsening of OSA. This bidirectional relationship between OSA and the endocrine system has been increasingly recognised in experimental and epidemiological studies and there are an increasing number of studies examining the effects of OSA treatment on endocrine conditions and vice versa. In this review article, we will critically appraise and describe the impact of OSA on the endocrine system including obesity, dysglycaemia, the pituitary, the thyroid, the adrenals, the reproductive system and the bones. In each section, we will assess whether a bidirectional relationship exists, and we will describe the potential underlying mechanisms. We have focused more on recent studies and randomised controlled trials where available and attempted to provide the information within clinical context and relevance.
Pasado y presente de un Centro Público Integrado de Galicia
Authors: Porto Castro Ana Mª , Sánchez Manso Isabel
Published: December 2018

La Ley Orgánica 1/1990, prevé el funcionamiento de centros integrados que abarcan dos o más niveles de enseñanza y el Real Decreto 1004/1991, de 14 de junio, en su Disposición adicional primera considera el funcionamiento de centros de diferentes enseñanzas en el mismo edificio o recinto escolar, determinando los espacios que son comunes y posibilitando formas organizativas más flexibles para adaptarse a las distintas situaciones que la realidad escolar puede presentar. En este marco, la Consellería de Educación e Ordenación Universitaria implanta y regula la existencia en la organización educativa de la Comunidad Autónoma de Galicia de los centros públicos integrados, CPI (Decreto 7/1999, de 7 de enero, DOG núm.16, martes 26 de enero de 1999).Reflexionar sobre estas cuestiones, las oportunidades que se derivan de la puesta en marcha de los centros públicos integrados para el alumnado y sus familias forma parte de los objetivos del presente artículo. Para ello se parte de un caso concreto, el actual CPI de Viaño Pequeno, situado en el municipio de Trazo. El relato de cómo se implantó este centro a través de la voz de una profesora que entonces formaba parte del cuadro docente, la información y los datos que proporciona, permiten hacer la crónica de una realidad que guarda muchas similitudes con la de los otros 53 centros públicos integrados distribuidos actualmente en la geografía de Galicia.Para dar cuenta de todo ello se realiza inicialmente una breve descripción geográfica y se presentan algunas notas que ayudan a situar el caso de este centro en el entorno concreto donde está ubicado y, al mismo tiempo, se señalan algunos acontecimientos sobre cómo se fue fraguando el proceso de implantación de un centro público integrado en un municipio rural gallego.
Temperature and salinity distribution of sea ice cover according to experimental and model data (case study of Novik Bay of the Sea of Japan)
Authors: Chetyrbotsky A. N. , Lazaryuk A. U.
Published: December 2018

Analysis of sample distributions of temperature and salinity within depths of sea ice allowed revealing a high negative correlation between temperature of the surface air layer and the salinity vertical distribution across the ice thickness. Tis situation is explained by the fact that when temperature inside the ice rises the vertically oriented pores flled with brine, and this causes increased ﬂow of brine. But when the temperature of the thickness drops, volumes of these pores signifcantly decrease, and as a result of that stresses near the pores grow and brine is squeezed out to both above and under the ice. Comparison of individual cases of the sample salinity distributions made possible to determine that the temperature of the surface air layer signifcantly inﬂuences the freezing intensity. When developing a model of spatiotemporal dynamics of the temperature, the diﬀusion mechanism of its vertical distribution is adopted, where the thermal conductivity coefcient is a linear function of temperature. A computational scheme for solving the model equations had been developed. Te procedure to estimate the model parameters is given. Te results of the parameter estimations had proved the adequacy of both the sample and the model distributions. A degree of the adequacy is the correlation coefcient between the above distributions. It is shown that the numerical simulation of the spatiotemporal salinity dynamics can be performed in framework of the diﬀusion mechanism of the vertical distribution, where the diﬀusion coefcient is a linear function of temperature. Te results of the parameter estimations did also show the adequacy of both the sample and the model distributions.
Polar Conference and Glaciological Symposium in Sochi, September 2018
Authors: Moskalevsky M. Yu. , Muraviev A. Ya.
Published: December 2018

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Optimizing Patient Management in Crohn’s Disease in a Tertiary Referral Center: the Impact of Fast-Track MRI on Patient Management and Outcomes
Authors: Ilias Akos , Lovasz Barbara D , Gonczi Lorant , Kurti Zsuzsanna , Vegh Zsuzsanna , Sumegi Liza D , Golovics Petra A , Rudas Gabor , Lakatos Peter L
Published: December 2018

Background & Aims: Rapid optimization of treatment algorithms and disease outcomes requires an objective measurement of disease activity in patients with Crohn’s disease (CD). Our aim was to evaluate the impact of rapid-access to magnetic resonance imaging (MRI) on treatment optimization, clinical decision-making and outcomes for CD patients in a specialized tertiary care for inflammatory bowel disease (IBD) patients.Methods: A cohort of 75 referral CD patients (median age: 34, IQR: 25-43 years) who had underwent 90 fasttrack MR enterography (MRE) scans between January 2014 and June 2016 were retrospectively enrolled. The MRI results were compared to clinical activity scores and biomarkers (C-reactive protein). The immediate impact of fast-track MRI on clinical decision-making, including changes in medical therapy, the need of hospitalization and surgery were evaluated.Results: The location of CD was ileo-colonic in 61% of the patients with perianal fistulas in 56% and previous surgeries in 55%. The indication for fast-track MRI scans was active disease (clinical or biomarker activity) in 55.6%. The radiological activity (including mild radiological signs to severe lesions) was detected in 94% of cases. Significant/severe MRI activity was depicted in 68% of these patients. Correlation between MRI radiological activity and clinical disease activity or colonoscopy was moderate (kappa: 0.609 and 0.652). A change in therapeutic strategy was made in 94.1% of cases with severe MRI radiological activity vs. 50% of patients without severe MRI radiological activity (p=0.001). Significant/severe MRI activity was followed by higher surgery rates among patients with clinical disease activity (50% vs. 12.5%; p=0.013). MRI performed on patients with clinical and biomarker remission identified disease activity in a significantly smaller proportion.Conclusions: Fast-track MRI had a great impact on patient management in CD patients with clinical or biomarker activity, leading to better patient stratification and faster optimization of the therapy (medical or surgical), while MRI revealed previously undiagnosed disease activity only in a small proportion of patients in clinical remission.
Severe Hepaticojejunostomy Dehiscence Treatment using a Shape-Modifying Covered Metal Stent with Single-Balloon Enteroscope
Authors: Inoue Tadahisa , Kitano Rena , Ito Kiyoaki , Yoneda Masashi
Published: December 2018

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Effects of aqueous extract of polyherbal formulation against hyperthyroidism induced by L-thyroxin in a rat model
Authors: Ahmed Sahar B. , Moghazy Asmaa M. , Ahmed-Farid Omar A. , Esebery Hassan A.
Published: December 2018

Background: Hyperthyroidism is a disorder that occurs when the thyroid gland secretes more thyroid hormone than the body needs. Thyroid hormone is essential for the normal growth and development of normal organs. Polyherb (POH) formulation has proven to be useful in number of diseases and has been used in folk medicine as an anti-hyperthyroidism, anti-oxidant, and appetitestimulating agent. The aim of the study was to evaluate the curative effect of POH against L-thyroxin (LT4)-induced hyperthyroidism in male rats.
Methods: Seven groups (10 rats each) were used for this purpose. Determination of phytochemical analysis, oxidative stress markers, brain appetite marker and cell energy marker were determined via high-performance liquid chromatography (HPLC) techniques. Thyroid hormones were detected via ELISA, and liver functions were determined by colorimetric method.
Results: The data showed that LT4 altered thyroid function via decreasing serum Thyroid-stimulating hormone (TSH), serum total protein, albumin and globulin, while increasing Triiodothyronine (T3), Thyroxine (T4), and Aspartate aminotransferase (AST). Moreover, oxidative stress markers in liver tissues were increased, via up-regulation of nitric oxide (NO), oxidized glutathione (GSSG), malondialdehyde (MDA), and 8-hydroxy-2'-deoxyguanosine (8OHdG). Meanwhile, glutathione (GSH) and ATP were alleviated; in contrast, metabolites of ADP and AMP were elevated. Neuronal appetite marker in brain tissue was decreased via low serotonin levels. On the other hand, rat groups treated with POH and Carbimazole (CBZ) showed markedly amelioration of hyperthyroidism in rats at low dose only but did not show complete amelioration at high dose of POH. The data were confirmed through histopathological examination of the thyroid.
Conclusion: The data obtained demonstrated that POH, at low dose, can be very effective for completely treating hyperthyroidism in rats, and was safer than Carbimazole (CBZ) and ameliorated most signaling pathways and in different tissues.
Neonatal Intubation Practice and Outcomes: An International Registry Study
Authors: Foglia Elizabeth E. , Ades Anne , Sawyer Taylor , Glass Kristen M. , Singh Neetu , Jung Philipp , Quek Bin Huey , Johnston Lindsay C. , Barry James , Zenge Jeanne , Moussa Ahmed , Kim Jae H. , DeMeo Stephen D. , Napolitano Natalie , Nadkarni Vinay , Nishisaki Akira ,   for the NEAR4NEOS Investigators
Published: December 2018

BACKGROUND AND OBJECTIVES:

Neonatal tracheal intubation is a critical but potentially dangerous procedure. We sought to characterize intubation practice and outcomes in the NICU and delivery room (DR) settings and to identify potentially modifiable factors to improve neonatal intubation safety.

METHODS:

We developed the National Emergency Airway Registry for Neonates and collected standardized data for patients, providers, practices, and outcomes of neonatal intubation. Safety outcomes included adverse tracheal intubation–associated events (TIAEs) and severe oxygen desaturation (≥20% decline in oxygen saturation). We examined the relationship between intubation characteristics and adverse events with univariable tests and multivariable logistic regression.

RESULTS:

We captured 2009 NICU intubations and 598 DR intubations from 10 centers. Pediatric residents attempted 15% of NICU and 2% of DR intubations. In the NICU, the first attempt success rate was 49%, adverse TIAE rate was 18%, and severe desaturation rate was 48%. In the DR, 46% of intubations were successful on the first attempt, with 17% TIAE rate and 31% severe desaturation rate. Site-specific TIAE rates ranged from 9% to 50% (P < .001), and severe desaturation rates ranged from 29% to 69% (P = .001). Practices independently associated with reduced TIAEs in the NICU included video laryngoscope (adjusted odds ratio 0.46, 95% confidence interval 0.28–0.73) and paralytic premedication (adjusted odds ratio 0.38, 95% confidence interval 0.25–0.57).

CONCLUSIONS:

We implemented a novel multisite neonatal intubation registry and identified potentially modifiable factors associated with adverse events. Our results will inform future interventional studies to improve neonatal intubation safety.
STRUCTURAL ANALYSIS OF LIQUID 3D TRANSITION METALS USING CHARGED HARD SPHERE REFERENCE SYSTEM
Authors: THAKOR P. B. , GAJJAR P. N. , JANI A. R.
Published: December 2018

The Charged Hard Sphere (CHS) reference system is applied to study the structural

analysis of liquid 3d transition metals. Here we report the structure factor S(q), pair

distribution function g (r), interatomic distance r1 of nearest neighbour atoms and coordination

number n$_1$ for liquid 3d transition metals viz: Ti, V, Cr, Mn, Fe, Co, Ni and Cu.

To describe electron–ion interaction our own model potential is employed alongwith the local

field correction due to Sarkar et al (SS). The present results of S(q) and g (r) are in

good agreement with experimental findings. The maximum discrepancy obtained from the

experimental data for the coordination number is 4.22% in the case of Ti while the lowest

is 0.31% for Cu. Thus CHS is capable of explaining the structural information of a nearly

empty d-shell, nearly filled d-shell and fully filled d-shell elements.
AXION IN PQWW MODEL AND AXION PRODUCTION IN e+e- COLLISION
Authors: SOA DANG VAN , THUC LE NHU , KHOI DINH PHAN
Published: December 2018

Properties of the axion in PQWW model is considered. In this model, axion appears as a new phase of the Higgs field. From a general Higgs potential which is renormalizable and invariant under UPQ(1) transformation, we consider the interaction of the axion with leptons and quarks. Based on these results, axion production in e+e- collision is calculated in detail. The numerical evaluation shows that the axion can be detected in

experimental conditions.
DEPENDENCE OF THE COSMIC MUON FLUX ON ATMOSPHERIC PRESSURE AND TEMPERATURE
Authors: DIEP PHAM NGOC , NHUNG PHAM THI TUYET , DINH PHAM NGOC , DUONG NGUYEN HAI , DARRIULAT PIERRE , THAO NGUYEN THI , THIEU DANG QUANG , THUAN VO VAN
Published: December 2018

The dependence upon atmospheric pressure of the cosmic muon flux in Hanoi

has been measured to be -1.47± 0.50 permil per mbar in agreement with expectation from a

naive estimate. The dependence over ground temperature is observed to largely reflect the

correlation existing between temperature and pressure. Once the effect of this correlation is

removed a smaller, barely significant temperature dependence of -0.57± 0.34 permil per °C

subsists.
QUALIDADE DE VIDA E BEM-ESTAR NO TRABALHO: AUTOPERCEPÇÃO DOS SERVIDORES DE UMA UNIVERSIDADE FEDERAL
Authors: Vieira Renato Paula Lopes , Madruga Lúcia Rejane Da Rosa Gama , Beuron Thiago Antônio , Ávila Lucas Veiga
Published: December 2018

O presente estudo tem como objetivo identificar a auto percepção dos servidores de uma Universidade Federal, quanto ao seu bem-estar no trabalho; e ainda, sugerir atividades com abordagens multidisciplinares visando a melhoria da qualidade de vida e o bem-estar no trabalho dos servidores. Para a realização deste estudo, optou-se por um levantamento em uma das subunidades acadêmicas, Centro de Artes e Letras (CAL), que possui 43 Servidores Técnico-Administrativos, alocados em níveis de apoio, intermediário e superior e com cargos administrativos e técnicos de nível de área afim, sobre qualidade de vida e bem-estar no trabalho. Quanto à abordagem de pesquisa, classifica-se como uma pesquisa qualitativa e quantitativa. A coleta de dados foi realizada por meio de instrumento elaborado com base no questionário desenvolvido e validado por Constantino (2007). Os principais achados revelam que os Servidores estão satisfeitos foi possível perceber que o Servidor TAE apresenta satisfação com sua qualidade de vida, o fator mais insatisfatório foi relacionado com atividades físicas o que suscitou a sugestão acerca da ginástica laboral.
IRMANDADE DOS COSSACOS DE PRUDENTÓPOLIS: UMA PROPOSTA DE PARTICIPAÇÃO COMUNITÁRIA
Authors: Matoso Silva Luciane Fontana , Dos Santos Josiane Rodrigues , Angnes Juliane Sachser
Published: December 2018

Este artigo aborda a participação comunitária à margem teórica da Psicologia Social Comunitária, destacando a Irmandade Cossacos de Prudentópolis, no estado do Paraná. A partir do estudo da origem, da constituição e da participação comunitária destacamos a trajetória da Irmandade. O intuito de estudá-la surgiu pelas peculiaridades dessa organização, as quais diferem das organizações tradicionais. O objetivo geral deste estudo foi compreender a história da Irmandade a partir da perspectiva dos membros do grupo e refletir sobre a participação comunitária na manutenção da tradição ucraniana. A Irmandade apresenta-se uma vez ao ano, na Páscoa, é composta por integrantes do sexo masculino e surgiu informalmente como forma de integração das pessoas na comunidade, após as cerimônias religiosas na Igreja São Josafat de Prudentópolis. Para esta investigação de abordagem qualitativa, utilizamos entrevistas semiestruturadas, pesquisa documental, observação e diário de campo. A partir dos trechos retirados das entrevistas, realizamos as análises e percebemos a constituição da Irmandade, tendo como base os conceitos trazidos pela Psicologia Social Comunitária da América Latina.
PROPOSTA METODOLÓGICA DE AVALIAÇÃO DA TÉCNICA DO AZUL DE METILENO NA AVALIAÇÃO DA QUALIDADE DA ÁGUA.
Authors: Silva Isabel do Nascimento , Almeida Janiele Mayara Ferreira de , Souza Sheila Pricila Marques Cabral de , Oliveira Érica Souza , Fernandes Nedja Suely
Published: December 2018

A água é indispensável para a vida na terra. No entanto, o crescimento populacional e a alta demanda podem levar à sua escassez. As ETEs (Estações de Tratamento de Esgoto) desempenham um bom papel no tratamento de águas residuais. Utilizou-se a técnica de avaliação da qualidade da água pelo método do Azul de Metileno (AM) no estudo da espectrofotometria da região do UV-vis, aplicada para avaliar a qualidade da água da ETE. A adsorção é uma das técnicas de tratamento de efluentes que mais se destaca devido sua eficiência e baixo custo. A literatura tem mostrado a importância do carvão de coco de babaçu no tratamento de efluentes têxteis. Para os estudos de adsorção, utilizou-se como material adsorvente o carvão de coco de babaçu modificado com ácido cítrico (CCBMod). O carvão sem modificação foi tratado com ácido cítrico por 4h, no qual após o processo foi lavado e filtrado até pH 7 e seco por 4h a 60° C. Para os testes de qualidade da água, quatro amostras foram colocadas em contato com o AM 1%, três amostras faziam parte das etapas de tratamento da ETE e uma referente a um padrão de água destilada e AM. Para os ensaios de adsorção do efluente real foram utilizados 100 mg de CCBMod e 30 ml de solução de AM. O teste do efluente da ETE para AM mostrou que após 14 dias a amostra A4 teve uma redução da cor do AM de 7,20%, enquanto que as amostras A3 e A2 tiveram uma redução de apenas 2,20%. O ensaio de adsorção mostrou que a remoção da cor no efluente foi de 57,86%, sendo o CCBMod eficaz na remoção de cor e a metodologia do AM eficaz no estudo da qualidade da água dos efluentes da ETE.
SOLIDARY SELECTIVE COLLECTION AND THE INTEGRATED MANAGEMENT OF SOLID WASTE IN THE MUNICIPALITIES FROM THE FLUMINENSE COUNTRYSIDE AND THE ROLE OF THE COURT OF JUSTICE
Authors: Alves Dayse , Ferreira da Silva José Augusto , Miranda Pinto Augusto Eduardo , Maurício Mauro Angelin dos Santos
Published: December 2018

By investing in the viability of social gains providing training and professional qualification aiming to sustainability, the Public Power promotes new values and attitudes that contribute to the improvement of the environment, citizenship and life quality. With this research it was sought to evaluate the collaborative role of the Court of Justice in implementing the solidary selective collection at Rio das Ostras’ County Forum, in accordance with its Sustainable Logistics Plan, with the law that instituted the National Policy on Solid Waste and the Federal Constitution, under the guiding principles of Environmental Law. The methodological strategy adopted is based on exploratory and descriptive research with bibliographic review and the evaluation of qualitative and quantitative data. The study revealed that the Judiciary is a great generator of paper waste, and that the Forum produces daily almost 20% of the average generation of the entire region and that the involvement of the whole society is needed.
RUSSIAN GENIUS LOMONOSOV AS A PIONEER AND POPULARIZER IN SCIENCE
Authors: Maevskaya Marina Igorevna , Gromova Ludmila Petrovna
Published: December 2018

The article analyzes the promotional activity of outstanding Russian encyclopedist Michail Lomonosov who founded the fundamentals of science in Russia and tried to make scientific knowledge available for the wide range of readers in the XVIII century. Also, different forms of dissemination of scientific knowledge that Lomonosov used in the academic and educational activities were examined in the article.
Artikel Dinamika Urban Sufisme di Indonesia: Continuity and Change dalam Majelis Shalawat Muhammad di Surabaya
Authors: Rubaidi Rubaidi
Published: December 2018

This paper discusses the phenomenon of urban sufism among the majelis Shalawat Muhammad under the murshid Gus Kahar in Surabaya with followers (disciples) spreading in various places especially East Java, even abroad. The theory of continuity and change is used to critically review Howell’s concept on urban sufism, and to present key concepts on sufism in its generic sense in terms of doctrine and empirical praxis. Although based in Surabaya, the doctrine and praxis of urban sufism in the Majelis Shalawat Muhammad reflects generic sufi teachings. The findings of this research reveal that the principle of continuity and change prevails in sufi tradition from time to time. This finding is different from Howell’s theory which stress on ritual dimension. The followers of Shalawat Muhammad emphasize more on education on the basis of praxis (sālik-sulūk, riyāḥah, and mujāhadah), in addition to the dimension of doctrine itself.
The Islamic Models of Saving and Investment sebagai Suatu Tawaran atas Perilaku Impulse Buying pada Produk dan Jasa Taḥsīnīyāt
Authors: Fauzia Ika Yunia
Published: December 2018

The behavior of impulsive buying becomes common today, along with the rampant variety of marketing promotions carried out by business people. Many consumers make purchases impulsively after being attracted to several factors that drive this behavior. The purchases due to unplanned decisions often occur in products and services of taḥsīnīyāt. Actually there is nothing wrong with the behavior of impulsive buying, if the consumers who do it have fulfilled the ḍarūrīyāt needs and have prepared their future needs. However, it becomes a problem if impulsive buying for products and services of taḥsīnīyāt precede the primary needs that have not been fulfilled properly. This research will try to provide a brief solution on how to limit the self from rughbah and shahwat of buying, by planning income for several financial posts. Here the author offers the concept of Islamic models of saving and investment which can also be interpreted as Islamic family wealth management. It is hoped that this research can provide a meaningful contribution to human developmen
Litigasi Hybrid Contract Gadai pada Lembaga Keuangan Syariah
Authors: Arifin Sirajul
Published: December 2018

The article examines the hybrid contract that is still debated although the contract has framed pawn products in Islamic financial institutions. The pawn system which has been regulated by the DSN-MUI, however, still leaves a problem. The problem arises because the mortgage system is a combination system of several contracts that require collateral. Collateral is used to build bank trust and the customer’s responsibility that the customer will return the loan in accordance with the contract. The used contracts are the loan, mortgage and lease agreements. If the financing in the mortgage system is default, the collateral item becomes the compensation for the repayment of the remaining debt of the customer. Pawn systems that require sublimation of several contracts in pawn products still become a subject of criticism. Hadiths about the prohibition of bay‘ and salaf, prohibitions requiring additional debt, and the prohibition of charging fees for collateral are those that criticize and are not aware of pawn hybrid contract. Even though the pawn hybrid contract is still criticized, the demand for contemporary transactions in sharia financial institutions cannot be ignored, even its presence is a necessity as long as it does not violate sharia norms and values.
Kritik Abdul Karim Amrullah terhadap Rābiṭah di Minangkabau dalam Tafsir Al-Burhān
Authors: Helfi Helfi
Published: December 2018

This article explores the thought of Abdul Karim Amrullah on the issue of rābiṭah in Minangkabau. He is regarded as very critical in responding social and cultural life, especially relating to tarekat. All behaviors of society should have basis from the Qur’an and Sunnah. All acts which are not based on the Qur’an and Sunnah are considered as innovation (bid‘ah) that should be avoided. Amrullah categorically rejected rābiṭah for there was no sharī‘ah basis for it, although the kaum tua (conservative) in Minangkabau attempted to conserve rābiṭah in their surau. Rābiṭah as one of wasīlah (mediator) is understood as a medium to reach God through substitute face. What is meant is the murshid who taught their followers to achieve the determined position in their own tarekat. Amrullah’s criticism towards rābiṭah in Minangkabau initially resulted in resistence, especially among the founder of tarekat. However, in the course of time the issue of tarekat declined, and even underwent significant decay in Minangkabau.