bluuebunny/crossref_metadata_2025 huggingface dataset:
β-Cell Secretory Capacity Predicts Metabolic Outcomes over 6 Years following Human Islet Transplantation
Authors: J. Flatt Anneliese , M. Matus Austin , J. Gallop Robert , Markmann Eileen , Dalton-Bakes Cornelia , J. Peleckis Amy , Liu Chengyang , Naji Ali , R. Rickels Michael
Published: December 2024

Transplanted islet functional β-cell mass is measured by the β-cell secretory capacity derived from the acute insulin response to glucose-potentiated arginine (AIRpot), however, data are limited beyond one-year post-transplant for individuals with type 1 diabetes. We evaluated changes in β-cell secretory capacity in a single-center longitudinal analysis and examined relationships with measures of islet cell hormone metabolism and clinical measures of graft function (mixed-meal tolerance test [MMTT] C-peptide, BETA-2 score, and continuous glucose monitoring [CGM]). Eleven individuals received purified human pancreatic islets over one or two intra-portal infusions to achieve insulin-independence and were followed over a median (IQR) 6 (5-7) years. β-cell secretory capacity remained stable over 3-years before declining. Fasting glucagon and proinsulin secretory ratios under glucose-potentiation were inversely correlated with AIRpot. A functional β-cell mass of 40% normal predicted insulin-independence and was strongly predicted by MMTT C-peptide-to-glucose and BETA-2 score. A functional β-cell mass of >20% predicted excellent glycemic outcomes including ≤1% time <60 mg/dL, ≤2% time >180 mg/dL and ≥90% time-in-range 70-180 mg/dL. β-cell replacement approaches should target a functional β-cell mass >40% to provide sufficient islet reserve for sustained insulin-independence. MMTT C-peptide-to-glucose and BETA-2 score can inform changes in functional β-cell mass in the clinical setting.
Understanding the ultrashort laser microwelding process of ceramics to metals by numerical and experimental investigations
Authors: Zhang Tao , Wu Ming , Jiang Qing , Yang Jin , Xu Jiayi , Yang Meng , Zhang Xiang , Pan Rui , Li Peng
Published: December 2024

Ultrashort laser microwelding is an advanced technology with significant potential and benefits for welding dissimilar materials, including ceramics and metals. Details of the microwelding process involving ceramics and metals with ultrashort lasers remain somewhat unclear, especially regarding phase transformation and the underlying mechanism of joint formation. In this study, we utilized the ultrashort laser microwelding technique to join sapphire and Invar alloy. We have developed a predictive numerical model to calculate the interfacial temperature during the laser irradiation process. The relative contributions of heat diffusion, heat radiation, and heat accumulation in the welding process of two materials were investigated under single and multiple pulses. Upon implementing laser pulse energies of 35, 40, and 50 μJ, the maximum temperatures of sapphire were 3027.8, 4179.89, and 4533.30 K, respectively. The maximum temperature of the Invar alloy exceeded the vaporization temperature (3223.15 K). This resulted in various phase transformations, including evaporation, ionization, and melting, that occurred on both substrates. These transformations also caused the intermixing and diffusion of materials. It then resulted in the formation of the final joint. Based on the findings, we aim to provide a more comprehensive understanding and practical applications of the ultrashort laser microwelding technique.
Robótica inclusiva para personas con TEA: Aprendizaje adaptado y creativo
Authors:   Universidad de Guayaquil - Ecuador, Yturralde Villagómez Juan Carlos , Díaz Vera Janeth Pilar ,   Universidad de Guayaquil - Ecuador, Palacios Ortiz Francisco Gerardo ,   Universidad de Guayaquil - Ecuador, Plúas Burgos Jessica Johanna ,   Universidad de Guayaquil – Ecuador, Chicaiza Guayta Silvia María ,   Universidad de Guayaquil - Ecuador, Padilla Gómez Renzo Rogelio ,   Universidad de Guayaquil – Ecuador, Crespo Mendoza Roberto Carlos ,   Universidad de Guayaquil – Ecuador
Published: December 2024

El Trastorno del Espectro Autista (TEA) es una condición del neurodesarrollo que afecta a las personas en diversas áreas, como la comunicación, la interacción social y la conducta. Las personas con TEA pueden experimentar dificultades para entender y responder a las señales sociales, lo que puede hacer que se enfrenten a desafíos en el ámbito educativo y social. Además, suelen presentar una manera de aprender y procesar la información diferente a la de sus pares, lo que puede hacer que requieran un enfoque educativo más personalizado y adaptado a sus necesidades.

Estas dificultades no deben verse como limitaciones, sino como oportunidades para desarrollar habilidades a través de métodos innovadores y accesibles. En este contexto, la robótica se presenta como una herramienta educativa poderosa que puede ser de gran beneficio para los estudiantes con TEA. La robótica no solo les ofrece una forma atractiva de aprender, sino que también promueve el desarrollo de habilidades cognitivas, emocionales y sociales. Al trabajar con robots, los estudiantes pueden mejorar su capacidad de resolución de problemas, su coordinación motora, y su capacidad de trabajar en equipo. Además, la programación en bloque, una metodología visual y sencilla, facilita el aprendizaje de conceptos abstractos de forma práctica y comprensible.
MAPEAMENTO DO RISCO DE CONTAMINAÇÃO DAS ÁGUAS SUBTERRÂNEAS DA REGIÃO DE PIRES DO RIO, GOIÁS, BRASIL
Authors: Toscani Rafael , Campos José Eloi Guimarães , Silva Priscila Sousa , Vieira Ciro Costa , Ferreira Álvaro Xavier , Matos Débora Rabelo
Published: December 2024

A sobrexploração e a contaminação dos mananciais hídricos estão constantemente em evidência devido à intensa ação antrópica, justificando estudos que indiquem as áreas mais suscetíveis à contaminação. Assim, o presente estudo tem como objetivo o mapeamento do risco de contaminação das águas subterrâneas na região de Pires do Rio, estado de Goiás. Para isso, foram analisadas e classificadas trinta amostras de água, coletadas principalmente em poços rasos, que evidenciaram indícios de contaminação, especialmente pelo alto teor de fosfato e/ou nitrato em 12 amostras. Com base nessa constatação, juntamente com a integração digital de dados geológicos, hidrogeológicos, geomorfológicos, pedológicos, de cobertura vegetal e de pontos potenciais de contaminação devido à ocupação humana, foi possível delimitar áreas com maior risco de contaminação. Como resultado, o mapeamento permitiu a classificação das áreas em baixo, moderado e elevado risco de contaminação dos aquíferos, sendo o efeito antrópico, especialmente nas proximidades de granjas de produção de aves, o principal agente contaminador.
Hubungan Perilaku Usahatani Petani Ubikayu terhadap Produktivitas Ubikayu di Kabupaten Lampung Tengah
Authors: Syafani Tyas Sekartiara , Effendi Irwan , Lestari Pratiwi Dwi , Azzahra Muchlisa Aswin
Published: December 2024

Perilaku usahatani merupakan tindakan atau kebiasaan petani dalam melakukan proses produksi, seperti teknik budidaya, penggunaan pupuk dan pestisida, pemeliharaan tanaman, pemanenan, pascapanen, dan pemasaran hasil pertanian. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis perilaku petani ubi kayu ditinjau dari aspek budidaya berdasarkan tingkat pengetahuan, sikap, dan keterampilan, serta menganalisis hubungannya dengan produktivitas ubikayu di Kabupaten Lampung Tengah. Penelitian dilaksanakan bulan April - September 2023 dengan metode survei. Responden penelitian ini adalah petani ubikayu sebanyak 60 orang di Kecamatan Seputih Raman dan Kecamatan Tegineneng, Kabupaten Lampung Tengah. Pemilihan lokasi ditentukan secara purposive dengan pertimbangan bahwa Kabupaten Lampung Tengah merupakan sentra produksi ubi kayu di Provinsi Lampung.  Data dalam penelitian ini dikumpulkan menggunakan kuesioner terstruktur. Metode analisis data yang digunakan adalah statistik deskriptif. Hasil penelitian menunjukkan bahwa perilaku petani ubikayu berdasarkan aspek pengetahuan, sikap, dan keterampilan dalam melakukan usahatani ubikayu di Kabupaten Lampung Tengah termasuk dalam kategori sedang.  Produksi ubikayu yang dihasilkan oleh petani di Kabupaten Lampung Tengah sebesar 17,77 ton dengan produktivitas sebesar 32,04 ton/ha dengan umur panen rata-rata 8 bulan. Terdapat hubungan yang positif antara perilaku petani dengan produktivitas ubikayu di Kabupaten Lampung Tengah.
Kata kunci : perilaku petani, produktivitas, ubikayu
Equilibrium dynamics of forest ecosystems taking into account the relationship between <>
Authors: Volodchenkova L.A. , Guts A.K.
Published: December 2024

The article examines Nash equilibria for forest ecosystems, taking into account the relationship between vegetation and soil within the framework of differential game theory.
DYNAMICS IN HARMONIOUS HUMAN-NATURE URBAN ECOSYSTEM MODEL FOR ENVIRONMENT SUSTAINABILITY: A REVIEW
Authors:   Faculty Of Design and Architecture, Universiti Putra Malaysia, Persiaran Universiti 2, 43400 Seri Kembangan, Selangor, WU Yuting , Azmi Athira ,   Department of Architecture, Faculty of Design and Architecture, Universtiti Putra Malaysia, Serdang, Selangor, Malaysia, Ibrahim Rahinah ,   Department of Architecture, Faculty of Design and Architecture, Universtiti Putra Malaysia, Serdang, Selangor, Malaysia, Abdulkareem Salih Sarah ,   Department of Architecture, Faculty of Design and Architecture, Universtiti Putra Malaysia, Serdang, Selangor, Malaysia, Abd Ghafar Azmiah ,   Department of Architecture, Faculty of Design and Architecture, Universtiti Putra Malaysia, Serdang, Selangor, Malaysia
Published: December 2024

In the face of growing urbanization, conflicts between human activities and the natural environment have resulted in increasingly evident problems, such as ecological degradation, excessive resource depletion, loss of biodiversity, and pollution. These issues pose a growing threat to the achievement of global sustainable development goals. This study is part of a larger study to create a liveable and sustainable urban environment. It aims to develop an urban ecosystem model for promoting harmony with nature by analyzing the latest literature research from 2019 to 2023 using the Systematic Literature Review method. This paper elucidates the newest research developments in urban design, urban ecosystems, and the pursuit of enhanced synergy harmonious humans with nature. Subsequently, from the cross-analysis method it presents a synthesized model proposing a harmonious human-nature ecosystem for urban design. This model advocates the cultivation of human natural identity, providing a framework to adapt, modify, and preserve the urban environment in harmony with nature. Such an approach is expected to enhance urban vitality, which is harmonious between humans and nature while maintaining ecological functions and biodiversity and ensuring efficiency, equity, socio-cultural, and aesthetic values. This study contributes to identifying, understanding, and resolving ecological imbalances arising from urbanization. The results are expected to benefit authorities in maintaining a healthy standard of living in rapidly urbanizing areas. Future research will combine methods such as field investigations and design practices to further refine this urban design proposal, providing support and guidance for a more comprehensive sustainable urban environmental development.
The Implications of Structured Physical and Sports Activity Programs in Reducing Aggressiveness in Prisoners – A Systematic Review Analysis
Authors:   Doctoral School of Psychology, Faculty of Physical Education and Sport, West University, Timisoara, Romania. Email: cosmin.tomescu@yahoo.com., Tomescu Cosmin Marian , Petracovschi Simona ,   Faculty of Physical Education and Sport, West University of Timisoara, Romania. Email: simona.petracovschi@e-uvt.ro., Negrea Cristian ,   Faculty of Physical Education and Sport, West University, Timisoara, Romania. Corresponding author: cosmin.tomescu@yahoo.com.
Published: December 2024

Structured and purposeful physical activity has demonstrated significant effects on personality traits and behaviors among offenders, especially in reducing maladaptive behaviors. The European Prison Rules strongly advocate for all prisoners to have regular access to organized sports and physical education. This systematic review aims to emphasize the role of physical activity in enhancing inmates’ ability to control aggression, which in turn boosts their chances of successful social reintegration and lowers the risk of recidivism by improving self-esteem and locus of control. The review included eight relevant studies sourced from scientific platforms, analyzing research published between 2000 and 2023. The studies targeted both adult and young male and female inmates, regardless of their ethnicity, all of whom participated in structured physical education and sports programs within a prison environment. These programs varied in terms of physical activity, focusing on resistance and strength training, and were consistently associated with reduced aggression, improved self-esteem, and other benefits directly related to life in detention. Through the redirection of aggressive impulses and the enhancement of self-esteem and locus of control, physical activity plays a crucial role in preventing and reducing the harmful consequences of aggressive behavior in incarcerated populations.
Keywords: physical activity, sports, prison, aggression control, self-esteem, locus of control
The Influence of Sleep on Athletes’ Body Recovery After Effort
Authors:   Department of Physical Education and Sport, Faculty of Science, Physical Education and Informatics, Polytechnica National University of Science and Technology, Bucharest, Romania. Email: bmihaela2108@yahoo.com., Butnariu Mihaela
Published: December 2024

The recovery of athletes’ body after effort is an essential component of sports training, alongside physical, technical, tactical, theoretical, and psychological preparation. Sleep is a natural and crucial means for post-effort recovery, if the quality and quantity requirements are met. The aim of this research is to investigate athletes’ perceptions and behaviors related to sleep and rest and how these affect sports performance. The research methods used were literature review, questionnaire survey, statistical-mathematical analysis and graphical representation. By analyzing the responses to a 9-question survey, the study aims to highlight the factors that affect sleep quality and the impact on recovery and overall performance. Specifically, the research seeks to identify correlations between hours of sleep, bedtime and wake-up routines, relaxation techniques and perceptions of sleep’s importance in physical recovery. The questionnaire included questions about sleep habits (sleep hours, bedtime, alarm use), perceived sleep quality and common issues (difficulty falling asleep, frequent waking); athletes’ perceptions of sleep’s influence on sports performance; factors that disrupt sleep and techniques used to improve sleep quality. The student-athletes who responded to our questionnaire do not have sufficient knowledge about sleep hygiene, meaning that coaches should focus more on providing information about athletes’ lifestyle, which include the importance of sleep for post-effort recovery, for their health and implicitly for improving sports performance. Athletes must realize that sleep should be a priority in their lifestyle, placing it in the same place with nutrition and training.
Keywords: effort, performance, recovery, sleep, athletes
As contribuições do sistema S sob a ótica da interpretação restritiva do Decreto n. 2.318/86
Authors: Mendes Gustavo Sarot , Ambrosio Felipe Augusto Rodrigues
Published: December 2024

Este artigo analisa a limitação da base de cálculo das contribuições destinadas a terceiros, que financiam o Sistema S, no teto de 20 (vinte) salários mínimos. O art. 4º da Lei nº 6.950/1981 define a limitação de 20 salários mínimos vigentes para a base de cálculo das contribuições previdenciárias e a terceiros. Porém, as contribuições que são destinadas para a Previdência Social passaram a não mais ter a limitação de teto, nos termos do art. 3º, Decreto nº 2.318/86, com expressivos impactos nos encargos mensais das empresas. Assim, a Fazenda Pública passou a entender que o dispositivo mais recente revogou a previsão da Lei nº 6.950 igualmente em relação às contribuições em favor de terceiros. Disso, advieram decisões do STJ favoravelmente pelo limite de 20 salários mínimos a tais tributos. Pende atualmente de julgamento o Tema 1079/STJ que definirá, com eficácia vinculante, se essas contribuições podem ser calculadas sobre a folha de pagamento ou devem ter a sua base limitada a 20 salários mínimos. O trabalho possui metodologia qualitativa com abordagem dedutiva, e enquanto a técnica de pesquisa, documentação bibliográfica, legislativa, jurisprudencial e estudo de caso, este sobre o REsp 1.570.980/SP. Conclui-se que, para além de impactar o orçamento de entidades paraestatais que promovem serviços públicos de elevada importância, a interpretação de que a limitação da base de cálculo das contribuições paraestatais não configura ilegalidade vem se somar à uma lista de precedentes do tribunal da cidadania, influenciando de forma direta e incisiva na arrecadação do erário público.
A administração pública do medo e a nova lei de improbidade administrativa (Lei 14.230/2021): impactos possíveis na tomada de decisões do administrador público
Authors: Iachitzki Jonas , Gonçalves Ane Elise Brandalise , Vipievski Junior José Mario
Published: December 2024

O presente artigo visa estudar a respeito da tomada de decisões do administrador público e a ocorrência de improbidade administrativa. Trata-se de problemática que incorre sobre o fenômeno conhecido como Direito Administrativo do Medo, que substancialmente prejudica as decisões na Administração Pública e, por conseguinte, prejudica aos gestores públicos, fazendo-se essencial buscar alternativas para melhor manejo das respostas conferidas em prol do interesse público primário. Dentre tais alternativas, sobressai-se a Lei n. 14.230/2021, que alterou a Lei de Improbidade Administrativa. Assim, eis o problema da pesquisa: a nova lei de improbidade administrativa (Lei n. 14.230/2021) é capaz de melhorar a tomada de decisões do administrador público? Para tanto, por meio de uma revisão bibliográfica, o artigo apresenta na primeira seção sobre o conceito geral de Direito Administrativo do Medo e a tomada de decisões, para, então, adentrar nos aspectos e mudanças principais da Lei n. 14.230/2021. Conclui-se que referida lei pode apresentar-se como uma forma de mitigação do Direito Administrativo do Medo, em melhorias à gestão pública.
Iodinated contrast dye–diluent combination exhibits longer time to full dye saturation compared to lidocaine, bupivacaine, and water in porcine cadaveric nervous tissue
Authors: Albano Victoria , Hon Stephanie , Parry Stephen , Garcia Cristina de Miguel
Published: December 2024

OBJECTIVE

Dye-diluent combinations have different nerve-staining behavior, making locoregional cadaveric dye study findings difficult to compare. The objective of this study was to quantify the effect of 4 diluents on nerve color saturation when used in combination with commercial food dye.

METHODS

48 unpreserved brachial plexus nerves were randomized into 4 diluent groups. Lidocaine, bupivacaine, iodinated contrast, and sterile water were combined with commercial food dye (10:1), and prosected nerves were immersed in one of these groups for 1, 15, 30, or 60 minutes. Images at baseline and at each timepoint were processed using ImageJ. Color saturation was divided into quartiles (dark, medium dark, medium light, or light). The percentage of nerve area stained in each quartile was compared using a 2-way ANOVA and post hoc Tukey test.

RESULTS

At 1 minute, water and bupivacaine had a higher percentage of area of dark saturation compared to contrast. At 15 and 30 minutes, dark and medium-dark saturation percentages of area were also larger in lidocaine, bupivacaine, and water compared to contrast. There were no differences in saturation percentages of areas between groups at 60 minutes. Within groups, all diluents had darker percentages of area saturation at 15, 30, and 60 minutes compared to minute 1.

CONCLUSIONS

In porcine nerves, the staining profiles of 2% lidocaine, 0.5% bupivacaine, and sterile water combined withcommercial food dye appear similar and may be used interchangeably after 15 minutes of exposure. When using iodinated contrast, exposures over 60 minutes yield comparable results to other diluents.

CLINICAL RELEVANCE

Diluents contribute to heterogeneous nerve-staining behavior and should be considered when comparing study outcomes. If contrast is used as the diluent in cadaveric studies with postoperative imaging, researchers should be aware of the significant delay to reach a saturation level comparable to other diluent combinations.
Pneumonitis with amivantamab in squamous cell lung cancer with EGFR exon 20 insertion mutation: a case report
Authors: Cruz Margarida Melo , Silva Ana Filipa , Raimundo Sara , Gomes Teresa
Published: December 2024

Background

Amivantamab is a human antibody targeting epidermal growth factor receptor (EGFR) and c-MET. It is approved in patients with advanced non-small cell lung cancer (NSCLC) with EGFR exon 20 insertion after progression with platinum-based chemotherapy. The most frequent adverse effects (AEs) are rash, infusion-related reactions, paronychia, and peripheral edema. Pneumonitis is a rare side effect, and there is no evidence about the possibility of reintroducing amivantamab after pulmonary toxicity.

Clinical case

A 56-year-old male was diagnosed with squamous cell lung cancer in 2021, with brain metastasis at diagnosis. The brain lesion was resected, and histopathologic assessment revealed metastasis from squamous cell lung cancer, and an exon 20 insertion mutation was identified. Chemotherapy with immunotherapy (carboplatin + paclitaxel + pembrolizumab) was initiated in October 2021, and progression was observed after three maintenance cycles. Amivantamab was started in May 2022, and partial response was observed after 2 months of treatment. In September 2022, the patient complained of dyspnea on exertion and dry cough. Computed tomography (CT) scan showed scattered ground-glass opacities. A pneumonitis grade 2 CTCAE was assumed, and corticosteroid therapy was started, with improvement in both symptoms and imaging abnormalities. After discussion with a multidisciplinary team, it was decided to restart treatment with amivantamab in January 2023 and there is no evidence of pulmonary toxicity to this date.

Conclusion

Amivantamab-related pneumonitis is a rare side effect and usually predicts drug discontinuation. In this clinical case, it was possible to reintroduce the drug without reoccurrence of the toxicity successfully. This possibility of reintroducing treatment after non-life-threatening toxicity occurs can be of great importance as therapeutic options for these patients are limited.
Understanding Geotechnical Embankment Washout Due to Overtopping: Insights From Physical Tests
Authors: Urbaniak Mikołaj , Zamiar Krzysztof , Kostecki Stanisław
Published: December 2024

Understanding the erosion process of an earth dam and flood embankment composed of noncohesive, homogeneous soils due to overflow is crucial for determining the quantity and rate of water release. This is necessary to assess the consequences of a failure, analyze the risk, and develop appropriate crisis management procedures. Despite numerous studies in this area, the process of breach evolution is not fully explored. The article presents the results of physical experiments carried out in the field laboratory of the Wrocław University of Science and Technology for a dam with a height of 0.50 m that closes a reservoir with a capacity of 14.4 m3, whose width is significantly greater than the final width of the breach. The scenario analyzed assumes that water overflows the embankment crest, as it is the most common cause of embankment failure based on dam disaster databases. At the same time, the amount of water accumulated in the reservoir is the largest possible for this scenario, suggesting that such a catastrophe may have the most severe consequences. Based on the results obtained from three experiments, four repeatable phases of erosion evolution were identified and described: (I) the initiation phase, (II) the vertical erosion phase, (III) the lateral erosion phase, divided into two cycles, and (IV) the reservoir emptying phase without further propagation of the breach. The outflow rate of the water from the reservoir was also analyzed, allowing the determination of the outflow hydrograph for each test. Hydrographs showed differences between individual experiments; however, the average erosion rate was similar for all tests. Furthermore, the final width of the breach created each time was between 2.2 and 2.5 H (where H is the height of the embankment) and the volume of eroded soil ranged from 0.52 to 0.59 m3. The article also highlights the methodology to calculate the water outflow hydrograph.
Caracterização da morbimortalidade relacionadas às doenças respiratórias nas regiões brasileiras
Authors: Santos Mariana Donate Moreira , Mendes Amanda Nayanne Campos , Souza Danielly Araújo , Andrade Silmara Nunes , Carvalho Natane Moreira de
Published: December 2024

Introdução: As doenças respiratórias (DR) são consideradas uma das principais afecções que causam morbidade ao homem. Podem ser classificadas em: infecciosas e não
infecciosas. Apresentam uma diversidade nas formas de manifestações, abrangendo todas as faixas etárias. São responsáveis por 8% do total de mortes em países desenvolvidos e 5% em países em desenvolvimento, responsáveis por grande parte das internações hospitalares. Objetivo: caracterizar e comparar o número de morbimortalidade causadas por doenças respiratórias no Brasil, nos anos de 2019 a 2020 pelo banco de dados do Departamento de Informática do Sistema Único de Saúde. Método: trata-se estudo epidemiológico, descritivo e quantitativo. Para levantamento do número de internações por doenças respiratórias foram utilizados dados provenientes do Sistema de Informação Hospitalar do Sistema Único de Saúde. Os dados foram apresentados por meio dos números absolutos e frequência relativa. Para análise estatística foram realizados o teste de Qui-Quadrado e Teste T. Resultados: houve diferença significativa entre os números de internações nos períodos propostos. O número de internações por doenças respiratórias de ambos os anos, 2019 e 2020 não foi associado à nenhuma das variáveis analisadas. Conclusão: este estudo apresentou uma queda significante nos números de internações por doenças respiratórias no ano de 2020 comparado com o ano de 2019.
Descritores: Doenças Respiratórias; Perfil de Saúde; COVID-19; Sistema Único de Saúde; Hospitalização
As vespas sociais no imaginário e na cultura popular: uma revisão narrativa
Authors: Tagliatti Maciel Tatiane , Corrêa Barbosa Bruno , Prezoto Fábio
Published: December 2024

Introdução: A relação entre os humanos e os insetos além de antiga é bastante diversa. Os insetos são usados como fonte de alimento, na indústria têxtil, na medicina e estão fortemente presentes na cultura de vários povos. No entanto, alguns insetos são mais preteridos que outros e, sabendo da má fama das vespas sociais. Objetivo: O estudo teve como objetivo investigar e apresentar como as vespas sociais são retratadas nas mais diversas áreas e como isso impacta na opinião popular sobre elas e outros insetos. Metodologia: Para isso, além de buscas na literatura científica, também foram usados comunicações pessoais e conhecimento prévio dos autores. Resultados e discussão: Foi possível notar que ao longo da história as vespas sociais tiveram grande participação nos mitos e crenças populares e que nos dias de hoje a forma como são representadas em filmes e notícias de TV parecem ser os fatores principais para sua má fama. Conclusão: Assim, fica clara a necessidade de uma força tarefa daqueles que o fazem, para conter essas percepções negativas dos insetos. Ideias simples como montar um blog ou postar fotos de insetos em redes sociais podem ajudar as pessoas a admirar esses animais através do conhecimento despertando o interesse para sua preservação.
Revisão narrativa sobre os benefícios da suplementação de probióticos e prebióticos em iogurte de leite de cabra
Authors: Evangelista-Barreto Norma Suely , Silva Bruna Vieira , Ribeiro Milena Gabriel , Souza Bárbara Caliane de Oliveira
Published: December 2024

Introdução: A adição de ingredientes funcionais em novas formulações permite a obtenção de produtos que promovam benefícios para a saúde dos consumidores, são nutritivos e apresentam grande expansão de mercado. Objetivo: Este estudo teve como objetivo revisar o potencial biotecnológico de iogurtes de leite de cabra probióticos e a utilização dos prebióticos Spirulina platensis e própolis na indústria de produtos lácteos e os benefícios associados a saúde. Metodologia: Foram selecionados artigos científicos nacionais e internacionais entre o período de 2018 a 2023 nas bases de dados, Science Direct, Scielo e Google Acadêmico, utilizando as palavras-chave probióticos, iogurte, leite de cabra, saúde, Spirulina platenses, própolis e benefícios. Resultados: O iogurte de leite de cabra fornece para o consumidor um alimento diferenciado no mercado, com melhores características nutricionais quando comparado ao iogurte convencional, devido ao alto valor nutritivo do leite caprino. Além disso, a inclusão de ingredientes funcionais como a própolis, Spirulina platensis e bactérias probióticas contribuem na diversificação de iogurtes, visto que a espirulina e a própolis podem atuar como prebióticos e juntamente com os probióticos melhorar a função intestinal e do sistema imunológico. Conclusão: nesta revisão demonstramos o potencial biotecnológico dos ingredientes funcionais espirulina, própolis e probióticos na elaboração de iogurtes de leite de cabra como uma proposta promissora para o desenvolvimento de novas formulações de iogurtes na indústria alimentícia.
Maquiagem Infantil: aspectos regulatórios, controle de qualidade, padrões de uso e segurança.
Authors: Camboim Brendha Lang , Garcia Cássia Virginia
Published: December 2024

O Brasil é um dos maiores mercados mundiais de cosméticos infantis, e há um grande interesse das crianças por produtos de beleza, o que chama a atenção de pais e autoridades sanitárias quanto à sua segurança. Desde 2018 as maquiagens infantis são isentas de registro no Brasil, e embora sejam normalmente associadas aos adultos, também são amplamente comercializadas para crianças, por isso podem ser vistas como brinquedos. Neste caso, o termo toy makeup é utilizado. As crianças têm a pele mais permeável, fina e imatura, o que as torna mais vulneráveis, sendo o uso precoce prejudicial à sua saúde, aumentando a incidência de alergias, irritações cutâneas e intoxicações por ingestão. O presente trabalho realiza uma revisão da literatura acerca das maquiagens infantis, ressaltando os aspectos regulatórios, a avaliação da segurança, os padrões de uso e seu controle de qualidade. Foram utilizadas as bases de dados Science Direct, Pubmed, Google Scholar e Springer, e ao total, foram selecionadas 49 referências. As crianças devem usar somente produtos infantis, e a maquiagem que vem com brinquedos não deve ser aplicada na pele. Os componentes da formulação que mais desencadeiam reações alérgicas são os conservantes, fragrâncias e metais, e o controle de qualidade relacionado à presença de metais em maquiagens é uma área ativa de pesquisa e atividade regulatória. Em média, 62% das crianças até 12 anos já utilizou maquiagem e o início do uso foi aos 4 anos de idade, sendo o principal motivo (75%) a vontade da própria criança. O produto mais utilizado é o esmalte (52%), seguido do batom (45%), e o menos utilizado é o delineador (11%). Existem legislações brasileiras atuais acerca das maquiagens infantis, e há uma diferenciação não somente no conceito de “maquiagem” e “brinquedo”, mas também nas exigências regulamentares a que estão sujeitos. Palavras-chaves: Toy makeup; Maquiagem infantil; Segurança; Regulação.
Chronic Use Safety of Agomelatine and Combinations: Impact on Hematological, Biochemical, and Histopathological Parameters in Gender-Specified Rats
Authors: Bachur Tatiana , Barroso Poliana , Alves Ana Paula , Braga Marcus , Cavalcante Débora , Chaves Filho Adriano , Jucá Paloma , Moraes Maria Elisabete , Aragao Gislei Frota , Macêdo Danielle
Published: December 2024

Introduction: Polypharmacy may lead to changes in the action profile and toxicity of medicines. Objective: This study evaluated the effect of the association of the antidepressant agomelatine (AGO) with losartan (LOS), simvastatin (SIM), and metformin (MET), after subchronic treatment, on hematological, biochemical, and histopathological parameters in Wistar rats. Methods: The animals were randomly divided into ten groups for each sex and treated for 90 days, per os, with saline, AGO, LOS, SIM, MET, or combinations (AGO+LOS, AGO+SIM, AGO+MET, LOS+SIM+MET, and AGO+LOS+SIM+MET). We evaluated hematological, biochemical, and histopathological parameters. Regarding hematological alterations, the main changes occurred in the erythrogram. Results: Females in polypharmacy were more prone to develop hematological and biochemical alterations. Hepatic and renal functions were the most affected among biochemical parameters. Agomelatine, in association, increased the risk of histopathological changes in males and females, especially in the liver, kidneys, and spleen. Females presented more intense hepatic histopathological changes when AGO was associated with SIM and MET. Females using MET or AGO+MET were more prone to develop histopathological changes than males. The spleen was significantly affected in females, corroborating erythrogram alterations. Conclusion: Agomelatine in association altered the safety profile of drugs, especially in females, indicating caution in their use in polypharmacy with commonly prescribed drugs.
Perspectives Historical and Contemporary on Employee Turnover: A Literature Review
Authors: Dos Santos Fortunato Wellington , Doria Calvosa Marcello Vinicius
Published: December 2024

For over a century, employee turnover has been a topic of interest for many researchers globally. This literature review primarily aimed to examine the evolution of employee turnover from the perspective of senior researchers and to discuss potential future research directions in the field. The methodology was qualitative, involving a comprehensive bibliographic review. Searches were conducted in databases such as Scopus, SciELO, PsycArticles, JSTOR, Wiley, ScienceDirect, and Google Scholar, resulting in the analysis of 77 articles from international journals ranked “Q1” in the Scimago Journal & Country Rank (2022 evaluation) and Brazilian journals from the “A” stratum of Qualis/CAPES (2017-2020 quadrennium). The key findings revealed that: (i) the historical evolution of turnover studies highlights the increasing interest in the topic and the pursuit of understanding its causes, characteristics, and consequences; (ii) initially, the phenomenon was addressed through individual characteristics and aspects, but research has evolved towards collective approaches at group, unit, and organizational levels; (iii) the studies analyzed in recent decades highlight the diversity of contexts across different continents, with a focus on cultural and value influences affecting turnover. The main conclusions indicate that, historically, the phenomenon of employee turnover began to be analyzed in the USA in the early 1900s, later evolving with the application of various theories, and contemporary research focuses on approaches that consider organizational and socio-cultural influences.
Análisis teórico de la economía informal en América Latina: una revisión
Authors: Surpachin Miranda Iván Enrique , Montoya Vargas Regulo , Lino Gamarra Augusto Homero , Medina Sotelo Cristian Gumercindo Medina Sotelo , Cueva-Quezada Nilton Isaias Cueva-Quezada
Published: December 2024

La economía informal o simplemente informalidad, es una realidad latente en los países en vías de desarrollo, los países latinoamericanos no son la excepción de este fenómeno social. El presente estudio analiza los aspectos teóricos más relevantes de la informalidad, sus características, impactos, pero sobre todo su contribución en el crecimiento económico. La metodología adoptada corresponde a una revisión sistemática, para lo cual se recurrió al método PRISMA, seleccionándose veintidós artículos relevantes de distintas bases de datos como Web of Science, Scopus y SciELO. Los resultados muestran que la economía informal tiene un impacto significativo en el crecimiento económico, que afecta negativamente la productividad, la generación de empleo formal y la recaudación de impuestos. Las conclusiones, evidencian que la economía informal impacta negativamente en el desarrollo económico de la región, debido a la falta de regulación, baja productividad, evasión fiscal y la falta de protección laboral. Para enfrentar este desafío, es crucial implementar políticas y estrategias que promuevan la educación y capacitación de los trabajadores informales, reduzcan las barreras administrativas y fiscales, mejoren la infraestructura y los servicios básicos, fortalezcan la fiscalización y fomenten la formalización de las empresas informales.
Mariconería y estrategias de lectura
Authors: Arango Orejuela Angie Andrea
Published: December 2024

Este texto, en tono reflexivo, es una exploración inicial derivada de la relectura del libro Maricones eminentes: Arenas, Lorca, Puig, y yo, de Jaime Manrique Ardila. En estas breves páginas se propone indagar cómo la mariconería y el gesto drag se convierten en herramientas para la crítica literaria, desafiando las normas de género y sexualidad a partir del despliegue de una estrategia de lectura basada en preguntas. Además, dispone líneas dialógicas con una selección transitoria de autores que ponen en tensión las identidades sexuales con respecto a los marcos representativos dominantes en la política, la cultura y la literatura.
Diode Laser Absorption Sensor for Ammonia Detection in a Shock Tube
Authors: Peng Yuzhe , Sun Wenting
Published: December 2024

With the improved availability and performance of low-cost near-infrared diode lasers, quantitative assessment of ammonia ([Formula: see text]) as a carbon-free fuel has been made more accessible and affordable in both laboratory research and field applications. In the present study, an absorption sensor for [Formula: see text] measurement was developed by exploiting the affordability and flexibility of a near-infrared fiber-coupled distributed feedback diode laser. The first objective of the present study was to address the incomplete spectroscopic data for the absorption feature near [Formula: see text] through the determination of line strengths and broadening coefficients with collisional partners including [Formula: see text], [Formula: see text], [Formula: see text], and Ar. Line shape characterization in both an absorption cell and a shock tube behind reflected shock waves was conducted to determine the temperature exponents of these broadening coefficients. The other objective was to demonstrate the capability of the sensor through [Formula: see text] detection in multicomponent mixtures and [Formula: see text] time-history measurements in the shock tube for investigating [Formula: see text] chemical kinetics at engine and gas-turbine-relevant conditions. The [Formula: see text] sensor developed in this study could serve as a cost-effective diagnostic tool for chemical kinetic measurements, combustion monitoring, and other applications where flexibility and robustness are prioritized.
Development and Test of AFT-Fuselage BLI Propulsor Experiment
Authors: Magrini Andrea , Allegretta Enrico , Battiston Andrea , Ponza Rita , Benini Ernesto , Alderman James
Published: December 2024

Aircraft boundary-layer ingestion (BLI) propulsion involves a deep mutual aerodynamic interaction between the embedded engines and the airframe. This paper presents wind-tunnel tests followed by numerical validation investigating the aerodynamic characteristics of a representative airframe model with tail-cone BLI propulsor. Starting from a reference fuselage and by means of several axisymmetric optimizations aimed at maximizing the ratio between the net force thrust power to BLI fan disk power, an optimized upswept fuselage geometry with a nonaxisymmetric aft nacelle are derived. The model is manufactured and tested in the Aircraft Research Association transonic wind-tunnel facility at Mach numbers from 0.20 to 0.80, measuring extensive flow data. A detailed computational fluid dynamics study is conducted to assess the ability of steady Reynolds-averaged Navier–Stokes solutions to replicate experimental data. Five grid resolutions for two topologies with three turbulence models are tested at low- and high-speed conditions. The computational fluid dynamics is generally able to reproduce with good accuracy the measured flowfield at the aerodynamic interface plane using a sufficient mesh resolution, with a higher sensitivity to the turbulence closures in areas affected by shear layers and flow separations.
Association Between Pediatric International Knee Documentation Committee Score and Sagittal Knee Biomechanical Testing Following Anterior Cruciate Ligament Reconstruction
Authors: Lin Eric H. , Katzel Mia , Liang Adriana , Wren Tishya
Published: December 2024

OBJECTIVE: The purpose of this study was to compare the Pediatric International Knee Documentation Committee (Pedi-IKDC) scores with sagittal knee kinematics and kinetics during the vertical drop jump test in pediatric athletes who had undergone primary unilateral anterior cruciate ligament reconstruction (ACLR) and determine if the two measures captured overlapping aspects of knee recovery.

DESIGN: This is a retrospective cohort study.

METHOD: Seventy pediatric athletes who recently underwent ACLR completed biomechanical testing and the Pedi-IKDC survey. Limb symmetry for peak knee flexion angle (PKF), peak external knee flexion moment (PEKFM), and integral of power absorption (IPA) were evaluated and compared to Pedi-IKDC score using multivariate linear regressions controlling for time since surgery. Inter-knee symmetry was calculated using a Limb Symmetry Index (LSI) by dividing the scores of the injured knee by the scores of the uninjured knee and multiplying by 100.

RESULTS: There was a statistically significant positive relationship between Pedi-IKDC and LSI in PKF ( R2 = .163, p =.001), PEKFM ( R2 = .067, p = 0.033), and IPA ( R2 = .087, p = .014), indicating that higher Pedi-IKDC scores were associated with greater biomechanical symmetry when controlled for time. There were weak and significant positive relationships between time since surgery and PEKFM ( R2 = .172, p < .001) and IPA ( R2 = .255, p < .001), indicating improved biomechanical testing the further along from surgery, but there was no statistical significance between time since surgery and Pedi-IKDC or PKF.

CONCLUSIONS: Pedi-IKDC and drop jump biomechanics were weakly related but mainly captured different aspects of recovery after ACLR. They can be considered as complementary tools when evaluating patients post-ACLR. JOSPT Open 2025;3(2): 1-7. Epub 4 December 2024. doi:10.2519/josptopen.2024.0073
Distal femoral physeal fracture-dislocation (Salter-Harris-I) in a newborn: A case report
Authors: Samanta Riya , Batta Nafisa Shakir , Abhinetri K. S. V. , Gupta Vikas
Published: December 2024

Physeal fractures in newborns are relative rare injuries, most often occurring as a result of birth trauma. Salter-Harris fractures of the distal femur should be treated as knee dislocation and, hence, as a medical emergency. A high index of suspicion for vascular injury should be present. Reduction, stabilization, and, if necessary, vascular repair should be carried out at the earliest to avoid permanent damage/deformity. We report a case of distal femoral physeal fracture and dislocation in a 2-day old neonate presenting with a swollen knee and decreased motion of the right lower extremity shortly after delivery.
КОГНИТИВНЫЕ СТРАТЕГИИ ПОВЕДЕНИЯ ЛИЧНОСТИ В ЦИФРОВОЙ СРЕДЕ
Authors: И.С. Лучинкина
Published: December 2024

Введение. В статье обсуждается проблема влияния цифрового пространства и цифровой среды на когнитивные стратегии младших школьников. Приведены и теоретически проанализированы особенности личности, включенной в цифровое пространство. В ходе эмпирического исследования выявлены достоверные различия по показателям внимательности, статистического представления, развитости воображения, способности к линейному различению и умозаключению на основе линейных связей и способности к быстрому реагированию. Более того, эмпирически выявлены различия между респондентами по показателям когнитивных стратегий: импульсивность, рефлексивность, гибкость мышления и ригидность. Материалы и методы. Основные методы исследования — анализ научной литературы, посвященной проблематике влияния цифровой среды на развитие личности; эмпирические методы исследования — анкетирование и психодиагностический инструментарий. Также для подтверждения достоверности результатов исследования использован статистический пакет SPSS-26. Результаты. Анализ результатов исследования позволил сделать вывод о том, что существуют различия по когнитивным показателям среди респондентов с различным уровнем цифровой активности. Обсуждение. Полученные результаты указывают на взаимосвязь активности цифрового поведения младшего школьника и уровня сформированности когнитивных стратегий. Заключение. Выявлено, что существуют различия по показателям внимательности, статистического представления, развитости воображения, способности к линейному различению и умозаключению на основе линейных связей, способности к быстрому реагированию, импульсивности, рефлексивности, гибкости мышления и ригидности респондентов с различным уровнем активности личнос-ти в цифровой среде. Ключевые слова: цифровая среда; цифровая активность; цифровое поведение; когнитивные стратегии; цифровизация. Основные положения: – расширено представление о влиянии цифровизации на личность, в том числе на ее когнитивные стратегии; – эмпирически исследованы когнитивные стратегии респондентов младшего школьного возраста с различным уровнем активности цифрового поведения.