bluuebunny/crossref_metadata_2025 huggingface dataset:
Interaction of magma and wet, unconsolidated sediments: a case study from Ilindenski Kamak, Chelopech Formation, Central Srednogorie
Authors: Velev Stefan , Gerdjikov Ianko , Vangelov Dian
Published: December 2021

The Ilindenski Kamak is situated along the Ilindenska river valley, northwest of Chelopech village, and is composed of different types of volcanic and volcaniclastic rocks, which are interbedded by sandstones and mudstones, all of Late Cretaceous age. The architecture of the pile of extrusive andesitic rocks is interpreted as a subaqueous cryptodome or sill. The presented research deals with a variety of volcanic facies: 1, coherent andesitic domain; 2, quench fragmented domain (closely packed peperites); 3, globular peperites developed at the contact of wet, unconsolidated sediments.
Klisura/Rozino granite, Central Sredna Gora: a part of the story of late Permian–Early Triassic extensional magmatic event
Authors: Lazarova Anna , Broska Igor , Svojtka Martin , Naydenov Kalin
Published: December 2021

Тhe late- to post-Variscan magmatic activity in the South Black See region took plaсe during a considerably long period of ca. 80 from Late Carboniferous up to Early–Mid Triassic as two episodes are distinguished. The obtained age of 253.6±1.6 Ma for the Klisura/Rozino granite gives further evidence of the contemporaneous intrusive and extrusive magmatism during late Permian and Early Triassic in the Sredna Gora and Balkan zones.
Инструкция по солидарности от Дина Спейда
Authors: Горбачева Мария
Published: December 2021

«Mutual Aid» представляет собой коллективную координацию по оказанию взаимопомощи, которая исходит из понимания бесполезности существующих систем (государства, политики, экономики). Также такая самоорганизация – прямое противопоставление концепции спасения, лежащей, например, в основе благотворительности и работы различных НПО, созданных в западном контексте для подавления масштабных движений XX века: за гражданские права, феминистского и других. Суть практики взаимопомощи можно описать такими слоганами как «Наша сила – в дерзости» и «Солидарность вместо благотворительности».
Synergistic antimicrobial activity of a novel cationic micelle L/D2 and imipenem against multidrug-resistant Acinetobacter baumannii
Authors: Zhong Guansheng , Zhang Yingjiao , Yu Kun , Wen Li , Lu Hongjiang , Zheng Yang
Published: December 2021

Background: The multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) has become one of the most important pathogens of nosocomial infection due to widespread use of broad spectrum antimicrobial drugs and immunosuppressor therapy. As polymyxins resistance emerges, developing novel effective antibacterial agents capable of overcoming multidrug resistance is urgently needed. Methods: In this study, biodegradable triblock copolymers of polyethylene glycol (PEG), guanidinium-functionalized polycarbonate and polylactide, PEG-PGC20-PLLA20 (L2) and PEG-PGC20-PDLA20 (D2), were utilized as antibacterial agents. Results: The copolymers self-assemble into micellar nanoparticles (L/D2), and exhibit broad-spectrum antibacterial activity against 20 clinically isolated multidrug-resistant A. baumannii strains. L/D2 had more rapid killing kinetics than conventional antibiotics imipenem and ceftazidime, and exhibited potent anti-biofilm activity. Repeated use of L/D2 did not induce drug resistance. From scanning electron microscopy and nucleic acid release analyses, L/D2 showed membrane-lytic mechanism. We also demonstrated that L/D2 was synergistically active with imipenem against MDR A. baumannii strains. Additionally, strong synergistic antibacterial activity was also observed for the combined use of L/D2 and imipenem in a MDR A. baumannii abdominal infection mouse model. Conclusions: Therefore, the combination of L/D2 and imipenem might be an alternative option for the prevention of nosocomial infection caused by A. baumannii.
Anti-Parkinson’s evaluation of Brassica juncea leaf extract and underlying mechanism of its phytochemicals
Authors: Saleem Uzma , Bibi Shabana , Shah Muhammad Ajmal , Ahmad Bashir , Saleem Ammara , Chauhdary Zunera , Anwar Fareeha , Javaid Nimra , Hira Sundas , Akhtar Muhammad Furqan , Shah Ghulam Mujtaba , Khan Muhammad Saad , Muhammad Haji , Qasim Muhammad , Alqarni Mohammad , Algarni Majed A. , Blundell Renald , Vargas-De-La-Cruz Celia , Herrera-Calderon Oscar , Alhasani Reem Hasaballah
Published: December 2021

Background: Parkinson’s disease (PD) is associated with progressive neuronal damage and dysfunction. Oxidative stress helps to regulate neurodegenerative and neuronal dysfunction. Natural compounds could attenuate oxidative stress in a variety of neurological disorders. B. juncea is a rich source of antioxidants. The present study aimed to evaluate the therapeutic potential of B. juncea leaves for the treatment of PD by applying behavioral, in vivo and in silico studies. For in vivo studies rats were divided into six groups (n = 6). Group-I served as normal control (vehicle control). Group-II was disease control (haloperidol 1 mg/kg). Group-III was kept as a standard group (L-Dopa 100 mg/kg + carbidopa 25 mg/kg). Groups (IV–VI) were the treatment groups, receiving extract at 200-, 400- and 600 mg/kg doses respectively, for 21 days orally. Results: In vivo study results showed that the extract was found to improve muscles strength, motor coordination, and balance in PD. These behavioral outcomes were consistent with the recovery of endogenous antioxidant defence in biochemical analysis which was further corroborated with histopathological ameliorations. Dopamine levels increased and monoamine oxidase B (MAO-B) levels decreased dose-dependently in the brain during the study. Herein, we performed molecular docking analysis of the proposed extracted phytochemicals has explained that four putative phytochemicals (sinapic acid, rutin, ferulic acid, and caffeic acid) have presented very good results in terms of protein-ligand binding interactions as well as absorption, distribution, metabolism, excretion & toxicity (ADMET) profile estimations. Conclusion: The undertaken study concluded the anti-Parkinson activity of B. juncea and further suggests developments on its isolated compounds in PD therapeutics.
The predictive potential of genetic single nucleotide polymorphisms in CBX4 for hepatocellular carcinoma survival
Authors: Zhu Xiao-Ying , Huang Mei-Jin , Su Qun-Ying , Wang Xiang-Zhizi , Wang Juan , Long Qin-Qin , Wu Xue-Min , Huang Xiao-Ying , Yao Jin-Guang , Long Xi-Dai
Published: December 2021

Background: Our previous studies have reported that polycomb chromobox 4 (CBX4) has a potential promoting hepatocellular carcinoma (HCC) angiogenesis and tumor progression. However, it is unclear whether genetic single-nucleotide polymorphisms (SNPs) in this gene are associated with HCC prognosis. Methods: We conducted a hospital-based two-phase study, including 598 patients with pathologically diagnosed HCC for the SNPs screening phase and 328 HCC patients for clinic significance validating phase, to elucidate the association between SNPs of CBX4 and the survival of HCC. The genotypes of CBX4 were tested using the SNaPshot method and the effects of CBX4 SNPs on HCC prognosis were analyzed using Kaplan–Meier survival model and Cox regression model. Results: A total of 33 SNPs were selected and genotyped in this study. We found the rs77447679 SNP was significantly related to survival in individuals with HCC. Specifically, survival was noticeably decreased in HCC patients who have mutant homozygote AA of this SNP (rs77447679-AA) compared with these with wild type (rs77447679-CC). An additive effect of rs77447679 polymorphism and aflatoxin B1 exposure level was also observed in the survival analyses of HCC cases. Furthermore, this SNP was positively correlated not only with tumor size, grade, stage, and microvessel density (correlation coefficient r = 0.17, 0.23, 0.23, and 0.42, respectively), but also with increasing CBX4 expression (r = 0.57). Interestingly, the mutant genotypes of rs77447679 can significantly improve the therapeutic response of HCC cases on post-operative adjuvant transarterial chemoembolization (pa-TACE), but wild type not. Conclusions: These data suggest that genetic polymorphisms in the CBX4 may be a prognostic biomarker for HCC, and the rs77447679 SNP is such a potential candidate.
An updated overview of the physiological and molecular responses of rice to anoxia
Authors: Adak Malay Kumar , Saha Indraneel , Dolui Debabrata , Hasanuzzaman Mirza
Published: December 2021

Waterlogging or flooding in agricultural soil constructs a complex abiotic stress-web in crop plants throughout the lowland agricultural system. In rice, a staple grain crop in the world, submergence creates a long-term and recurrent problem for crops withstanding and their succeeding productivity. Therefore, to restore a satisfactory yield instead of a failure of crop in such submerged areas, the analysis of plants’ responses is important. Such analysis will facilitate research about the entity components of plants responses to anoxia or submergence. For example, the development of cellular and molecular cascade in gene expression of ROS signaling and its subsequent responses may lead to either tolerance or susceptibility in plants. Interplay of plant growth regulators [e.g., ethylene (ET), abscisic acid (ABA), gibberellic acid (GA) etc.] is the well-recognized residues in the coordination of signaling, its transmission through cellular network, and finally, modulation of gene expression are the keys to such tolerance. Nucleotide elements that are specifically sensitive to ethylene have been rescued from land-races of aus-type group of rice (Oryza sativa) and those are considered as the prime determinants for tolerance against anoxia. In this comprehensive text, we tried to accommodate and revise the fundamental and pivotal mechanisms of submergence stress at different angles of physiological and cellular responses of plants. These have also been reviewed for modern state of art techniques deciphering the molecular rejoinders like microRNA, protein-protein interaction, feedback regulation of expression, sugar sensing, amplification of elicitor’s responses and others. Finally, strategies including physiological selection, metabolic engineering, marker assisted selection, genetical manipulation, interspecific hybridization are involved in developing stress resilience and plants’ architecture to support sustainable agriculture under lowland systems.
Immunogenicity and safety of SARS-CoV-2 vaccines in clinical trials
Authors: Lim Hui Xuan , Arip Masita , Yahaya Abdul Aziz Al-Fattah , Jazayeri Seyed Davoud , Poppema Sibrandes , Poh Chit Laa
Published: December 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were first detected in Wuhan, China in December 2019 and resulted in a worldwide pandemic in 2020. SARS-CoV-2 infections totalled more than 180 million with 3.9 million deaths as of June 24, 2021. Tremendous research efforts have resulted in the development of at least 64 vaccine candidates that have reached Phase I to III clinical trials within 14 months. The primary efficacy endpoint for a random placebo-controlled clinical trial of a COVID-19 vaccine to be approved by US FDA should confer at least 50% protection against COVID-19. Three COVID-19 vaccines (BNT162b2, mRNA-1273 and Sputnik V) in clinical Phase III trials have now achieved >90% efficacy in preventing COVID-19. Since SARS-CoV-2 is highly contagious, vaccines are expected to achieve at least 80% herd immunity in the world’s population to effectively prevent SARS-CoV-2 infections. An overview of safety, immunogenicity and efficacy of the current frontrunner vaccines are reviewed.
Nutrition, atherosclerosis, arterial imaging, cardiovascular risk stratification, and manifestations in COVID-19 framework: a narrative review
Authors: Munjral Smiksha , Ahluwalia Puneet , Jamthikar Ankush D. , Puvvula Anudeep , Saba Luca , Faa Gavino , Singh Inder M , Chadha Paramjit S. , Turk Monika , Johri Amer M. , Khanna Narendra N , Viskovic Klaudija , Mavrogeni Sophie , Laird John R , Pareek Gyan , Miner Martin , Sobel David W. , Balestrieri Antonella , Sfikakis Petros P , Tsoulfas George , Protogerou Athanasios , Misra Prasanna , Agarwal Vikas , Kitas George D. , Kolluri Raghu , Teji Jagjit , Al-Maini Mustafa , Dhanjil Surinder K. , Sockalingam Meyypan , Saxena Ajit , Sharma Aditya , Rathore Vijay , Fatemi Mostafa , Alizad Azra , Viswanathan Vijay , Krishnan P K , Omerzu Tomaz , Naidu Subbaram , Nicolaides Andrew , Suri Jasjit S.
Published: December 2021

Background: Atherosclerosis is the primary cause of the cardiovascular disease (CVD). Several risk factors lead to atherosclerosis, and altered nutrition is one among those. Nutrition has been ignored quite often in the process of CVD risk assessment. Altered nutrition along with carotid ultrasound imaging-driven atherosclerotic plaque features can help in understanding and banishing the problems associated with the late diagnosis of CVD. Artificial intelligence (AI) is another promisingly adopted technology for CVD risk assessment and management. Therefore, we hypothesize that the risk of atherosclerotic CVD can be accurately monitored using carotid ultrasound imaging, predicted using AI-based algorithms, and reduced with the help of proper nutrition. Layout: The review presents a pathophysiological link between nutrition and atherosclerosis by gaining a deep insight into the processes involved at each stage of plaque development. After targeting the causes and finding out results by low-cost, user-friendly, ultrasound-based arterial imaging, it is important to (i) stratify the risks and (ii) monitor them by measuring plaque burden and computing risk score as part of the preventive framework. Artificial intelligence (AI)-based strategies are used to provide efficient CVD risk assessments. Finally, the review presents the role of AI for CVD risk assessment during COVID-19. Conclusions: By studying the mechanism of low-density lipoprotein formation, saturated and trans fat, and other dietary components that lead to plaque formation, we demonstrate the use of CVD risk assessment due to nutrition and atherosclerosis disease formation during normal and COVID times. Further, nutrition if included, as a part of the associated risk factors can benefit from atherosclerotic disease progression and its management using AI-based CVD risk assessment.
Safety Assessment of Cuticle Remover Cosmetics In Vivo and In Vitro
Authors: Lee Kee-Young , Kim Min-Kyung , Kim Jeong-Hee
Published: December 2021

Recently, the issue of the harmful effects of nail care products has been posed. In case of cuticle remover, information on hazards of chemical substances is limited and product safety reports are also insufficient. This study evaluated the safety of the top three commercially selling cuticle removers that are widely used in nail care: Blue cross, Zero cleanser and Flower vita cuticle cares. To measure the pH level of cuticle remover cosmetics, distilled water and DMEM. The toxic effect of cuticle removers on cultured HaCaT was identified by MTT-assay. The patch test was performed to evaluate the occurrence of erythema on the patch area according to the criteria of ICDRG after applying the cuticle remover cosmetics (as is). Adherence to the cosmetic pH measurement guidelines, it w as confirmed that the blue cross product did not meet the pH standard of the final product of the domestic cosmetic method. When measuring the pH by diluting DMEM with a solvent, Flower vita product maintained a pH close to Neutral 7.0 overall. All three cuticle removers demonstrated dose-dependent cytotoxic on HaCaT cell. The viability of cells treated with 10 μg/mL Blue cross or 10 μg/mL Zero cleanser was presented below 10%. Otherwise, Flower vita treatment at concentrations of 0.5~20 μg up to 20 μg/mL did not affect the viability (above 70%) in the HaCaT. Of the patch test, there was positive in one case (3.3%) at 2 weeks. It was observed that a doubful reaction (-/+) to Flower vita and weak positive reactions (+) to Blue cross, and zero cleanser. Taken together, it was shown that the Flower vita product have the lowest cytotoxicity in HaCaT cells and slight allergic reaction, proving more safer than other tw o products in vivo and in vitro.
Research Trends in Hair-related Dissertations over the Past Decade - Focused on papers published in 2011~2020 -
Authors: Lee Ho-Jin , Noh Young-Hee
Published: December 2021

In this study, we will analyze academic research trends over the past 10 years in line with the development and education of the beauty industry and provide direction and basic data for future especially hair research. It was limited to master's and doctorate papers registered in the Research Information Service System (RISS) in March 2021 among beauty and beauty research papers published in 2011 and 2020. The keyword (Keyword) was categorized by hair, makeup, skin, and nail majors that can currently obtain a national technical certificate, and 2,878 were first searched. The research was conducted three times a week on March 8, 15, and March 22, 2021, with no difference in search results. The analysis of the papers studied was conducted for four months from March 2021 to June 2021. There were 1,558 skin-related thesis (54.1%), 610 hair-related thesis (21.2%), 379 makeup-related thesis (13.2%), and 331 nail-related thesis (11.5%). Among them, the distribution of hair-related thesis found to be 518 masters and 92 doctors. Looking at the topic of master's thesis, hair behaviors 217 (41.8%), hair design 208 (40.1%). doctor's thesis by topic, hair behaviors 39 (44.3%), hair design 29 (32.2%). According to a survey of research methods, 255 surveys (49.2%), 138 literature studies (26.6%), and 80 works (15.4%). The Ph.D. thesis showed 41 surveys (45.6%), 24 works (26.7%) and 9 literature studies (10%). In addition, 278 of the master's thesis were surveyed and 177 (63.7%) for consumers and 83 (29.9%) for workers. According to the classification of 47 doctoral thesis, 25consumers (53.2%) and 17 workers (36.2%). According to a survey of 34 master's experimental studies, 21 clinical trials (61.8%), 13 non-clinical trials (38.2%), 14 doctoral experimental studies (35.7%), and 9 non-clinical trials (64.3%). In the future, the scope of analysis will be expanded to major fields such as skin, makeup, and nails, and academic papers as well as academic papers will be required to be analyzed. Furthermore, it is possible to conduct a more diverse and objective analysis of research trends in the beauty field if research trends at home and abroad are grasped.
Influence of Beauty Service Workers' Psychological Capital on Their Creative Behavior According to Empowerment and Shared Leadership
Authors: Kim Ji-Young , Han Chae-Jeong
Published: December 2021

This study looks into the influence of psychological capital of beauty service industry workers on their creative behavior and aims to empirically investigate causal relationships between variables by identifying the influence of empowerment and shared leadership, which are the mediator variables. For this purpose, convenient sampling was conducted on beauty service industry workers, and 711 was chosen as the final sample. The sampled data were analyzed using SPSS 24.0 and AMOS 23.0 programs. As a result, psychological capital was confirmed to have influence over empowerment with no direct influence on shared leadership and creative behavior but indirect influence mediated by empowerment on them. It was further confirmed that psychological capital has indirect influence mediated by empowerment and shared leadership. On the other hand, empowerment was found to have an influence on shared leadership and creative behavior, with also shared leadership having a significant influence on creative behavior.
Trường Đại học Đồng Tháp tiếp tục phát huy hiệu quả đào tạo giáo viên tiểu học để đáp ứng yêu cầu đổi mới giáo dục phổ thông
Authors: Nguyễn Văn Bản
Published: December 2021

Đào tạo giáo viên tiểu học trình độ đại học của Trường Đại học Đồng Tháp mười lăm năm qua đã đóng góp tích cực phát triển đội ngũ giáo viên cho vùng Đồng bằng sông Cửu Long và các địa phương khác. Từ những thành tựu, hạn chế và nguyên nhân, bài báo đề xuất một số giải pháp nhằm phát huy hiệu quả đào tạo giáo viên tiểu học đáp ứng yêu cầu của đổi mới giáo dục phổ thông sau năm 2018.
Vận dụng lý thuyết đa trí tuệ tổ chức dạy học bài Tự nhiên - Xã hội bằng sơ đồ tư duy
Authors: Dương Huy Cẩn
Published: December 2021

Tổ chức dạy học theo lý thuyết đa trí tuệ bằng sơ đồ tư duy có tác dụng kích thích tính tích cực học tập, tìm tòi nghiên cứu, phát triển năng lực và kỹ năng học tập cho học sinh. Phát triển trí tuệ của học sinh trong học tập theo năng lực của từng cá nhân phù hợp với nội dung học tập góp phần thực hiện mục tiêu và chất lượng dạy học. Bài báo trình bày tóm tắt về lý thuyết đa trí tuệ, sơ đồ tư duy trong dạy học và cách vận dụng lý thuyết đa trí tuệ bằng sơ đồ tư duy trong dạy học các môn Tự nhiên và Xã hội lớp 1, 2, 3; Khoa học lớp 4, 5; Lịch sử và Địa lý lớp 4, 5 (Tự nhiên - Xã hội) ở tiểu học để phát triển năng lực học tập cho học sinh.
Thiết kế dự án học tập chủ đề động vật cho học sinh lớp 5 trong hoạt động trải nghiệm sáng tạo
Authors: Nguyễn Thị Minh Mẫn , Nguyễn Thị Tường Vi
Published: December 2021

Dạy học chủ đề động vật là một trong những nội dung hết sức gần gũi, thiết thực đối với học sinh tiểu học nói chung và học sinh lớp 5 nói riêng. Nội dung dạy học chủ đề động vật ở lớp 5 sẽ giúp học sinh nắm được những kiến thức về sự sinh sản và nuôi dạy con của các loài vật. Một trong những hình thức dạy học phát huy tích cực năng lực của học sinh được biết đến những năm gần đây chính là dạy học theo dự án. Ở phạm vi bài viết này, chúng tôi xin giới thiệu về vấn đề thiết kế dự án học tập chủ đề động vật cho học sinh lớp 5 trong hoạt động trải nghiệm sáng tạo.
Thiết kế đề cương chi tiết học phần để tổ chức dạy học nhất quán với chuẩn đầu ra chương trình
Authors: Nguyễn Hữu Duyệt
Published: December 2021

Bài báo trình bày quan điểm mới về mục tiêu, vai trò, nguyên tắc và quy trình thiết kế đề cương chi tiết học phần để tổ chức dạy học nhất quán với chuẩn đầu ra chương trình. Theo đó giới thiệu mẫu cấu trúc đề cương chi tiết học phần đã được sử dụng chính thức tại Trường Đại học Đồng Tháp, góp phần đổi mới phương pháp dạy học, giúp sinh viên chủ động tự học và đáp ứng nhu cầu đào tạo đã được cam kết trong chuẩn đầu ra của từng ngành đào tạo.
Dạy học theo định hướng phát triển năng lực phát hiện và giải quyết vấn đề cho sinh viên ngành Sư phạm Ngữ văn
Authors: Võ Thị Trang
Published: December 2021

Bài viết đề cập đến vấn đề dạy học theo định hướng phát triển năng lực phát hiện và giải quyết vấn đề cho sinh viên ngành Sư phạm Ngữ văn. Trong đó, người viết đề cập đến bản chất, các bước và những định hướng dạy học theo hướng phát triển nănglực phát hiện và giải quyết vấn đề. Hoạt động dạy học này giúp sinh viên phát triển tư duy giải quyết các vấn đề trong học tập, giảng dạy sau này cũng như các vấn đề trong cuộc sống.
Các dịch vụ hệ sinh thái của rừng ngập mặn tại Tiền Giang đối với người dân địa phương
Authors: Nguyễn Công Tráng , Trương Quốc Trọng , Ngô Thị Trang Đài
Published: December 2021

Rừng ngập mặn là một hệ sinh thái vô cùng quan trọng đối với đời sống của người dân vùng ven biển Việt Nam. Tiền Giang, có diện tích rừng ngập mặn là 1.500 ha đã hỗ trợ rất lớn cho kinh tế của các hộ dân trong vùng. Kết quả nghiên cứu xác định các dịch vụ hệ sinh thái quan trọng đối với cuộc sống của người dân tại địa phương, trong đó có 3 nhóm dịch vụ hệ sinh thái rừng ngập mặn được người dân đánh giá với mức độ quan trọng là dịch vụ cung cấp (2,54/3 điểm), dịch vụ điều tiết (2,39/3 điểm), dịch vụ hỗ trợ (2,26/3 điểm). Đây là nghiên cứu đầu tiên tại Tiền Giang về vai trò của rừng ngập mặn đối với người dân địa phương.
Deaths in custody in Australia 2020-21
Authors: Doherty Laura
Published: December 2021

The National Deaths in Custody Program has monitored the extent and nature of deaths occurring in prison, police custody and youth detention in Australia since 1980. The Australian Institute of Criminology has coordinated the program since its establishment in 1992, the result of a recommendation made the previous year by the Royal Commission into Aboriginal Deaths in Custody. In 2020–21 there were 82 deaths in custody: 66 in prison custody and 16 in police custody or custody-related operations. This report contains detailed information on these deaths and compares the findings with longer term trends.
THE ESSENCE OF ADMINISTRATIVE AND LEGAL MEANS OF STRUGGLE WITH DRUG TRAFFICKING OFFENSES
Authors: Huminsky M.
Published: December 2021

The article discusses theoretical approaches to the content of the concept of administrative and legal means of combating offenses in the field of drug trafficking, provides the author's definition of the desired concept. The emphasis is made on the features of the use of persuasion methods and methods of coercion in law enforcement, criteria for the classification of persuasive methods are highlighted, and their effectiveness is assessed.
The impact of performance audit planning on the generation of added value, management of public financial resources and heritage. Theoretical aspects and practical approaches
Authors: Dolghii C.
Published: December 2021

The performance audit is an effective instrument in the process of managing public money by analyzing a border range of matters, conducting an objective and independent evaluation of the extent to which public funding is used using the principles of economy, efficiency, effectiveness. The progress of performance audit in the Republic of Moldova is as well a priority because the allocation of public resources takes place to achieve social and economic objectives, but having regard to that resources are limited and allocated as a result of setting priorities and needs, they are managed based on the principles of "3E". In this regard, the auditors, at the performance audit planning stage, exclude the risk that the audit activities will not be proficient or efficacious, and the results of the audit will not add value to the public entity in managing public financial resources and public heritage. The author, in this study, examines the quality assurance of the processes performed during the performance audit planning stage and proposes to the auditors the use of other tools practiced in developed countries in selecting entities/programs or activities for auditing with the implementation of professional judgment.
METHODOLOGY FOR ASSESSING THE LOGISTIC POTENTIAL OF THE REGONS OF THE REPUBLIC OF BELARUS
Authors: Romankova T.
Published: December 2021

The article provides a comparative analysis of the definitions of "logistics potential", considers the structure of the logistics potential of the region. The author proposes and substantiates the indicators for assessing each structural element of the logistics potential (spatial, transit, transport, personnel and storage). A methodology for assessing the logistics potential has been developed and its level has been calculated in the context of the regions of the Republic of Belarus. Based on the results of the calculations, the ranks of the regions of the republic for the development of logistics potential were established, which made it possible to develop the main directions for increasing the logistics potential of the Grodno region, which ranks last in the ranking of regions in terms of the development of logistics potential.
EEC ACTIVITIES TO PREVENT VIOLATIONS OF THE GENERAL RULES OF COMPETITION IN CROSS-BORDER MARKETS
Authors: Nekrashevich H.
Published: December 2021

The article presents a study of the activities of the Eurasian Economic Commission in the field of suppressing anticompetitive conduct restoring a level playing field in the cross-border markets of the Eurasian Economic Union. The study is provides an overview and classification of the most widely used performance indicators of the antimonopoly agency based on world practice. The reasons for the inexpediency, and sometimes the impossibility of using most of them in order to assess the performance of the supranational antimonopoly authority of the Eurasian Economic Union, are indicated. It is analyzed what indicators of the work of the Eurasian Economic Commission can give an objective assessment of the effectiveness of its activities based on the available data. The article presents the results of assessing the activities of the supranational antimonopoly authority according to various criteria in the field of considering the cases of a potential violation of the general rules of competition in cross-border markets for 2016-2019. It is concluded that as a whole the antimonopoly policy of the integration grouping successfully copes with the task of suppressing anti-competitive behavior and restoring fair competition and meets international standards, despite a number of difficulties in this area.
LABOR MIGRATION IN THE REPUBLIC OF BELARUS: THEORY AND PRACTICE UNDER MODERN CONDITIONS
Authors: Tikhonova L. , Pugachev V.
Published: December 2021

The article analyzes methodological approaches to assessing the impact of factors of international labor migration on the socio-economic development of the country. The analysis of the state and dynamics of changes in indicators of international labor migration in the Republic of Belarus is carried out on the basis of the use of official statistical data of the competent authorities. Conclusions are made about the influence of the parameters of international labor migration on the national labor market of Belarus in modern conditions.
METHODOLOGY FOR MODELING THE BEHAVIOR OF AN ENTERPRISE IN A COMPETITIVE ENVIRONMENT
Authors: Shavlyuga O.
Published: December 2021

The article deals with the issues of modeling the behavior of an enterprise in a competitive environment, provides an overview of approaches to the concept of a competitive environment, an analysis of literary sources devoted to this topic. An urgent issue for modern enterprises is timely adaptation to market changes and the behavior of competitors. The author's methodology for modeling the behavior of an enterprise in a competitive environment is proposed, focused on taking into account the dynamism of the external environment, analyzing the activities of competitors and developing appropriate marketing scenarios, which includes the following tools: a matrix of scenarios for the behavior of an enterprise in the market relative to competitors; a set of criteria for analyzing competitors; classification of types of competitors; a set of typical scenarios for countering competitors. The author offers a classification of factors (market, consumer, production) that influence the competitive environment and the prospects for the development of the enterprise in the market.
HUBUNGAN KUALITAS PERAWATAN KATETER DENGAN KEJADIAN INFEKSI NOSOKOMIAL SALURAN KEMIH DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA MEDAN TAHUN 2019
Authors: Magdalena T. Bolon Christina
Published: December 2021

ABSTRAK

Infeksi nosokomial merupakan kejadian yang sering terjadi di rumah sakit dan dapat menimbulkan kerugian bagi pasien, keluarga dan rumah sakit itu sendiri. Salah satu infeksi nosokomial yang sering terjadi adalah infeksi saluran kemih pada pasien-pasien yang terpasang dower kateter. Faktor-faktor yang menyebabkan infeksi nosokomial saluran kemih antara lain hospes, agent, prosedur pemasangan, lama kateter terpasang dan kualitas perawatan kateter.Penelitian ini bertujuan untuk mengetahui hubungan kualitas perawatan kateter dengan kejadian infeksi nosokomial saluran kemih.Metode penelitian ini adalah observasi dan menggunakan instrunen penelitian berupa lembar kusioner.Variable bebas dalam penelitian ini adalah kualitas perawatan kateter dan variable terikatnya adalah kejadian infeksi nosokomial saluran kemih.Subjek penelitian adalah perawat yang memiliki pendidikan DIII dan S1 keperawatan, pasien yang, terpasang dower kateter, diagnosa masuk bukan ISK.Hasil penelitian menunjukan bahwa kualitas perawatan kateter terbanyak adalah cukup (56,7%), baik (40,0%) dan kurang (3,3%). Angka kejadian infeksi nosokomial saluran kemih yang mendapatkan perawatan kateter dengan kualitas cukup sebesar 3.33% dan, kurang 3,33%.Untuk menekan kejadian infeksi nosokomial saluran kemih akibat pemasangan kateter perlu adanya peningkatan kualitas perawatan kateter sesuai dengan standar prosedur perawatan dan prosedur pencegahan infeksi.Uji statistik menggunakan uji Chi Square untuk menilai hubungan antara kualitas perawatan kateter dengan kejadian infeksi nosokomial saluran kemih. Hasil analisis dengan uji chi square dengan hasil yang di peroleh nilai P<0,001 (<0,05) yang menunjukan ada hubungan kualitas perawatan kateter dengan kejadian infeksi nosokomial saluran kemih.
TINGKAT PENGETAHUAN IBU NIFAS TENTANG MANFAAT SENAM NIFAS DI LINGKUNGAN IX DESA CINTA RAKYAT KECAMATAN PERCUT SEI TUAN KABUPATEN DELI SERDANG
Authors: Hutagaol Aureliya
Published: December 2021

ABSTRAK

Senam nifas adalah senam yang dilakukan ibu-ibu setelah melahirkan sampai keadaan tubuhnya pulih kembali. Senam nifas dilaksanakan setelah kondisi ibu benar-benar pulih kembali dan tidak ada keluhan-keluhan ataupun gejala-gejala akibat kehamilan persalinan yang lalu. Senam nifas dapat dilakukan oleh semua ibu yang telah melahirkan secara spontan tanpa adanya komplikasi atau kondisi-kondisi diatas, senam nifas tetap dijalankan tetapi perlu disesuaikan dengan kondisi dan komplikasi yang terjadi. Tujuan penelitian ini adalah untuk mengetahui tingkat pengetahuan ibu nifas tentang manfaat senam nifas berdasarkan pengertian, cara/tekhnik dan manfaat dari senam nifas. Jenis penelitian ini bersifat deskriptif observasional dengan menggunakan data primer. Penelitian ini dilakukan di Lingkungan IX Desa Cinta Rakyat Kecamatan Percut Sei Tuan Kabupaten Deli Serdang, periode Januari – Maret 2020. Populasi penelitian ini adalah seluruh ibu nifas di Lingkungan IX Desa Cinta Rakyat, yang berjumlah 30 orang. Pengambilan sampel dilakukan dengan menggunakan tekhnik total sampling, dimana seluruh populasi dijadikan sampel yaitu sebanyak 30 orang. Pengambilan data ini menggunakan kuesioner (pernyataan) dengan jumlah 20 soal. Berdasarkan hasil penelitian dapat disimpulkan bahwa berdasarkan hasil kuesioner (pernyataan) mayoritas responden yang menjawab benar adalah pernyataan nomor 11 tentang cara melakukan latihan penguat perut sebanyak 26 responden (86,7%) dan berdasarkan pengetahuan diperoleh mayoritas ibu nifas yang berpengetahuan kurang sebanyak 17 responden (56,7%). Bagi petugas kesehatan diharapkan untuk lebih meningkatkan mutu pelayanan kesehatan dan mengadakan penyuluhan tentang manfaat senam nifas pada ibu nifas.
EKSPRESI EMOSI KELUARGA YANG MERAWAT PASIEN SKIZOFRENIA
Authors: Pardede Jek Amidos
Published: December 2021

Expression of emotions in the family can be an expression that reflects the high expression of negative emotions. Expressions of high emotion show an attitude that is full of criticism and hatred. It arises when parents or other family members assume that the disorder is influenced by internal factors and must be controlled by the individual. This study aims to determine the emotional expression of the family of schizophrenic patients in the mental hospital. Prof. dr. Muhammad Ildrem Medan. The research design used was descriptive with a cross-sectional approach. The population in this study were all families who have family members with outpatient schizophrenia patients at Prof. dr. Muhammad Ildrem Mental Hospital in Medan as many as 900 people. The sample of this research is 90 families. The sampling technique uses purposive sampling. The data collection tool used a questionnaire of 18 statements that had been tested for validity and reliability. The results showed the majority of respondents who treated patients had low emotional expressions, and the majority of respondents who treated more than one patient had high emotional expressions. Therefore, this research is expected to give attention to the families of sick family members to assist them in healing their illnesses.
EFEKTIFITAS TERAPI KOMUNIKASI TERAPEUTIK TERHADAP TINGKAT KECEMASAN PADA PASIEN GAGAL JANTUNG DI RUMAH SAKIT ROYAL PRIMA PADA TAHUN 2020
Authors: Noradina
Published: December 2021

Gagal jantung adalah keadaan patofisiologik dimana jantung sebagai pompa tidak mampu memenuhi kebutuhan darah untuk metabolisme jaringan.Gagal jantung merupakan tahap akhir dari sebuah penyakit jantung dan merupakan penyebab peningkatan morbiditas dan mortalitas pasien jantung.Pasien gagal jantung banyak yang mengalami kecemasan ringan sampai dengan berat.Kecemasan dan perasaan takut yang dialami pasien dapat berkurang dengan terapi komunikasi terapeutik.Tujuan penelitan untuk mengetahui efektifitas terapi komunikasi terapeutik terhadap tingkat kecemasan pada pasien gagal jantung di Rumah Sakit Royal Prima Tahun 2020. Jenis penelitan bersifat quasy eksperimen dengan desain cross sectional. Populasi dalam penelitian adalah pasien gagal jantung di Rumah Sakit Royal Prima Tahun 2020 sebanyak 25 orang. Teknik pengambilan sampel menggunakan teknik total sampling  sebanyak 25 orang. Hasil penelitian diperoleh hasil variable sebelum mayoritas kecemasan tingkat panik sebanyak 15 orang (60%), minoritas kecemasan tingkat berat sebanyak 10 orang (40%). Variabel sesudah minoritas kecemasan tingkat sedang sebanyak 15 orang (60%), minoritas kecemasan tingkat berat sebanyak 1 orang (4%). Hasil uji Wilcoxon  dengan nilai p value  = 0.000, maka P < 0,05 maka Ho titolak. Kesimpulan dari penelitian yaitu ada efektifitas terapi komunikasi terapeutik terhadap tingkat kecemasan sangat baik pada pasien gagal jantung di Rumah Sakit Royal Prima Tahun 2020. Diharapkan bagi responden agar menjalin komunikasi terapeutik dengan baik sehingga responden dapat menghilangkan pikiran-pikiran yang negative dengan cara saling berkomunikasi dengan perawat sehingga tingkat kecemasan responden dapat berkurang.
STUDI LITERATUR: PENGARUH TERAPI PIJAT REFLEKSI KAKI TERHADAP KELELAHAN PADA PASIEN HEMODIALISIS
Authors: Fajar Pamungkas Latif , Hamid Wada Fauziah , Astuti Puji , Prima Ashar
Published: December 2021

Hemodialysis can cause various kinds of problems including fatigue, around 7-92% of hemodialysis patients experience fatigue. One of the therapies that can overcome this fatigue is reflexology foot massage therapy. This literature review aims to determine the effect of foot reflexology massage on hemodialysis patients with fatigue problems. The design in this scientific paper is a literature review search using electronic data base namely ProQuest and Pubmed. The keywords used in the search are hemodialysis, foot reflexology, fatigue. inclusion criteria used in the article are accessible full text available in english and indonesian years the articles used are limited to the last ten years, results are found each of 2 articles from google schoolar and pubmed, from the four articles discussing the effectiveness of foot reflexology massage on the decline fatigue in hemodialysis patients. The results of the study showed the benefits of foot reflexology in reducing fatigue in hemodialysis patients
PENGARUH MANAJEMEN STRES TERHADAP PENURUNAN KADAR GULA DARAH PADA PENDERITA DIABETES MELLITUS DI DESA CINTA RAKYAT KECAMATAN PERCUT SEI TUAN KABUPATEN DELI SERDANG TAHUN 2020
Authors: Putra Ritonga Edisyah , Ningsih Rizky Wahyu
Published: December 2021

Milletus diabetes is an emergency in a condition that is concerned with increased blood and specific specific symptoms, namely urine that tastes sweet and in large quantities. Stress is the body's response that is not specific to every need that is not disturbed, a universal phenomenon that occurs in everyday life and cannot be avoided, every person who experiences it, stress has a total impact on the individual, namely physical, psychological, intellectual, social and spiritually, stress can threaten the physiological balance. The type of research used in this research is quantitative by using a quasi experimental research design with the type of One Group Pretest-Posttest Design. The population in this study were residents of hamlet IX and hamlet X in Cinta Rakyat village, the total population in this study were 30 people with Diabetes Milletus disease. The sample size of this study is the entire population according to the criteria set in 30 people with Diabetes Milletus. Univariate and bivariate data analysis using the Wilcoxon Test. a significant value of 0.002 which means that it indicates acceptance and value (α = 0.005) = 0.002 <0.005. It is expected that residents and also respondents in IX and X Dusun Cinta Rakyat Village must be able to carry out non-pharmacological stress management therapy at home so that diabetes mellitus can be prevented.
GAMBARAN PENGETAHUAN PASIEN TUBERCULOSIS PARU TENTANG PUTUS OAT (OBAT ANTI TUBERCULOSIS) DI RSU IPI MEDAN TAHUN 2019
Authors: Sitorus Jenti
Published: December 2021

Pulmonary tuberculosis is an infectious disease that attacks the lungs which is typically characterized by the formation of granulomas causing tissue neocrosis. Pulmonary tuberculosis is caused by "mycrobacterium tuberculosis" a type of rod-shaped germ with a length of 1-4 / mm and a thickness of 0.3 -0.6 / mm. The World Health Organization (WHO) in 2007 stated that the number of tuberculosis sufferers in Indonesia was around 528 thousand or in third place in the world after India and China. The WHO report in 2009 recorded Indonesia's ranking according to fifth position with the number of tuberculosis sufferers of 429 thousand people, namely India, China, South Africa, Nigeria, and Indonesia (source WHO Global Tuberculosis Control 2010). This study aims to describe the knowledge of pulmonary tuberculosis patients about anti-tuberculosis drug withdrawal at RSU IPI Medan who is experiencing pulmonary tuberculosis. The sampling technique used in this research is Probability Sampling with the Random Sampling technique. Then the number of samples is 40 respondents. researchers used primary data. With the results of the study, it is hoped that respondents will increase their knowledge by finding out and caring about the health of others in order to prevent the transmission of pulmonary tuberculosis and change bad behavior for the better, with the participation and cooperation of medical personnel and other health teams in provide precise and accurate information.
EFEKTIVITAS PEMBERIAN KESEHATAN THE HEALTH BELIEF MODEL TERHADAP PENGETAHUAN KELUARGA TENTANG TB PARU DI RS TNI AL Dr. KOMANG MAKES BELAWAN
Authors: Magdalena T. Bolon Christina , Viska Renata Pasaribu  , Rostinah Manurung  , Paskah Rina Situmorang
Published: December 2021

Pulmonary tuberculosis (TB) is an infectious disease in the lungs caused by bacteria, namely Mycobacterium tuberculosis. The number of pulmonary TB cases in Dr. Komang Makes Belawan as many as 23 patients. The high number of morbid cases is thought to have a lack of family understanding of TB sufferers regarding the concept of prevention and treatment of pulmonary tuberculosis accompanied by ineffective implementation of education by nurses. The research objective was to determine the effectiveness of health provision by applying The Health Belief Model to the knowledge of families with pulmonary tuberculosis. This research was conducted at the TNI AL Dr. Komang Makes Belawan was conducted starting July 2020. This type of research was a quasi-experimental design with a pre-test-post-test without a control group design. The population was 23 people with pulmonary tuberculosis patients and all of them were used as research samples. The results showed that the average score of knowledge before being given health education by implementing the Health Belief Model with leafelt (intervention) counseling was 11.47 and increased to 15.00 after the intervention with an average of 3.53. The results of the paired t test analysis showed that health education with the application of The Health Belief Model was effective in increasing the knowledge of families with pulmonary tuberculosis with a p value of 0.000 <0.05. The conclusion is that there are differences in family knowledge about pulmonary TB before and after getting health education The Health Belief Model.
Probing Systems: Art in Early 1970s Hungary
Authors: Thyssen Esther T
Published: December 2021

Artworks in a range of media show how the postwar generation created a unique voice, symptomatic for Hungary under state socialism, while disordering the boundaries imposed by the Tiltott, Tűrt, Támogatott [Banned, tolerated, promoted] system. Artists in Hungary found ways to move forward despite the challenges presented by socialist policies, censorship, punishment, and financial precarity. Their resources included state-provided art education, day jobs, and travel; unofficial mentors; and private exhibition venues and ingenious use of public spaces. Absorbing the importance of constructivism and abstraction from the historical avant-garde, the younger artists embraced geometric abstraction as the concept of the origin of postwar art. Once they internalized the system of abstraction, they could exchange its elements (the square, the cube, the line) for visual idioms from folk art, political symbols, and nature itself. Artists Imre Bak, Gábor Attalai, and the Pécs Workshop represent this cultural legacy. Scholarship on the art of the early 1970s predominantly follows the markers artists had set for themselves—to emphasize the artistic interchange with the West—but in the current context of reframing global modernism, the systems of visual languages in Hungary deserve attention.
Why Did Hungarian Politics Become Authoritarian? A Review of Competing and Complementary Responses
Authors: Fábián Katalin
Published: December 2021

This review essay introduces and compares six English-language scholarly monographs that analyze the emergence of illiberal rule in Hungary since 2010. Placing the converging arguments of these books in a comparative international context highlights the deep gulf between the official, self-congratulatory, and broadly accepted Hungarian perspective and the more critical academic interpretations published abroad.
Sleep quality of medical students at a college in the south of Minas Gerais
Authors: Roma Pedro Fernandes , Medeiros Glenia Junqueira Machado , Matos Pedro Henrique Meirelles Ferreira Pinheiro de
Published: December 2021

Introduction: Sleep is a physiological state that occurs cyclically in many living beings, analyzing rest and activity behaviors, which make up a wake-sleep cycle. At the university, medical students are faced with a lack of time and exhaustion, since the course has a full workload, a fact that causes students to leave basic activities more and more towards the end of the day, thus developing disorders of the sleep. Objective: The objective of this study is to analyze the quality of sleep and the incidence of sleep disorder in medical students. Design and setting: The research was carried out with students from a medical school in the south of Minas Gerais. Methods: The Google Forms platform was used by students to answer two self-administered questionnaires. The first encompassed questions about gender and year of graduation and the second assessed sleep quality and is called the Pittsburgh Sleep Quality Index. The Bioestat 5 and Excel 365 were used for statistical analysis. Results: The analysis of the PSQI results showed sleep disturbance in 20.5% of the students, presence of poor sleep quality in 47.2% of the students, 40.2% of students had poor or very poor subjective quality of sleep. Conclusion: Through this research, it was observed that the sleep quality of medical students is lower than that of the general population, being related to the progression of the course. It was concluded that the students in this study also have, on average, fewer hours of sleep than the rest of Brazilians.