bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis and Evaluation of Some New Substituted Benzothiazepine and Benzoxazepine Derivatives as Anticonvulsant Agents.
Authors: Garg Neha , Chandra Trilok , Archana Archana , Jain Amit B. , Kumar Ashok
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iridium(III)‐Catalyzed Enantioselective Si—H Bond Insertion and Formation of an Enantioenriched Silicon Center.
Authors: Yasutomi Yoichi , Suematsu Hidehiro , Katsuki Tsutomu
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Synthesis of P‐Stereogenic Heterocycles via Enyne Ring‐Closing Metathesis.
Authors: Harvey James Stephen , Giuffredi Guy T. , Gouverneur Veronique
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iron‐Catalyzed Synthesis of Selenoesters from Diselenides and Acyl Chlorides or Acid Anhydrides in the Presence of Magnesium Dust.
Authors: Ren Kai , Wang Min , Liu Ping , Wang Lei
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 3‐Oxo‐11β‐hydroxyfriedelane from the Roots of Celastrus monospermus
Authors: Chen Ming‐Xiang , Wang Ding‐Yong , Guo Jiao
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Biomimetic Syntheses from Squalene‐Like Precursors: Synthesis of ent‐Abudinol B (I) and Reassessment of the Structure of Muzitone.
Authors: Boone Matthew A. , Tong Rongbiao , McDonald Frank E. , Lense Sheri , Cao Rui , Hardcastle Kenneth I.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diastereoselective Allylstannane Additions to (S)‐5,6‐Dihydro‐2H‐5‐phenyloxazin‐2‐one. A Concise Synthesis of (S)‐β‐Methylisoleucine.
Authors: Pigza Julie A. , Molinski Tadeusz F.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Microwave‐Assisted Conversion of D‐Glucose into Lactic Acid under Solvent‐Free Conditions.
Authors: Epane Geraldine , Laguerre Jean Claude , Wadouachi Anne , Marek Delphine
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Tandem Prins/Schmidt Reaction Approach to Marine Alkaloids: Formal and Total Syntheses of Lepadiformines A (XVI) and C (XVII).
Authors: Meyer Angelica M. , Katz Christopher E. , Li Sze‐Wan , Vander Velde David , Aube Jeffrey
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (.+‐.)‐ and (‐)‐Actinophyllic Acid.
Authors: Martin Connor L. , Overman Larry E. , Rohde Jason M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Saikachinoside A, a Novel 3‐Prenylated Isoguanine Glucoside from Seeds of Gleditsia japonica
Authors: Kajimoto Tadashi , Aoki Nobuwa , Ohta Emi , Kawai Yasushi , Ohta Shinji
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two Novel Nucleosidyl—Peptide Antibiotics: Sansanmycin F and G Produced by Streptomyces sp SS
Authors: Xie Yunying , Xu Hongzhang , Sun Chenghang , Yu Ying , Chen Ruxian
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Rugulosins, anti‐MRSA Antibiotics, Produced by Penicillium radicum FKI‐3765‐2.
Authors: Yamazaki Hiroyuki , Koyama Nobuhiro , Omura Satoshi , Tomoda Hiroshi
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Anthelmintic Constituents of Clonostachys candelabrum
Authors: Ayers Sloan , Zink Deborah L. , Mohn Kenneth , Powell Joanne S. , Brown Christine M. , Bills Gerald , Grund Alan , Thompson Donald , Singh Sheo B.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: MnOx Nanoparticles Supported on a New Mesostructured Silicate with Textural Porosity.
Authors: Tusar Natasa Novak , Ristic Alenka , Mali Gregor , Mazaj Matjaz , Arcon Iztok , Arcon Denis , Kaucic Venceslav , Logar Natasa Zabukovec
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Challenges for Rechargeable Li Batteries
Authors: Goodenough John B. , Kim Youngsik
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Bulk Materials for Thermoelectric Power Generation: Clathrates and Complex Antimonides
Authors: Kleinke Holger
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Zintl Chemistry for Designing High Efficiency Thermoelectric Materials.
Authors: Toberer Eric S. , May Andrew F. , Snyder G. Jeffrey
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Geometrical Frustration Effects in the Two‐Dimensional Triangular‐Lattice Antiferromagnet NiGa2S4 and Related Compounds
Authors: Nakatsuji Satoru , Nambu Yusuke , Onoda Shigeki
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Quantum Kagome Antiferromagnet ZnCu3(OH)6Cl2
Authors: Mendels Philippe , Bert Fabrice
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Multiferroicity — The Coupling Between Magnetic and Polarization Orders
Authors: Wang K. F. , Liu J.‐M. , Ren Z. F.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Magnetic Nanoparticle Assemblies
Authors: Kechrakos Dimitris
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cs—P System
Authors: Sangster James M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold Compounds as Anticancer Agents: Chemistry, Cellular Pharmacology, and Preclinical Studies
Authors: Nobili Stefania , Mini Enrico , Landini Ida , Gabbiani Chiara , Casini Angela , Messori Luigi
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 119Sn NMR Spectroscopic and Structural Properties of Transition Metal Complexes with Terminal Stannylene Ligands
Authors: Agustin Dominique , Ehses Markus
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metallocenium Salts of Transition Metal Bisdichalcogenate Anions — Structure and Magnetic Properties
Authors: Gama V. , Almeida M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Molecular Architecture for Electrically Conducting Materials Based on Unsymmetrical Organometallic—Dithiolene Complexes
Authors: Kubo Kazuya , Kato Reizo
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Gold(III) Complexes with Nitrogen and Oxygen Ligands
Authors: Cinellu Maria Agostina
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ionic‐Liquid‐Supported (ILS) Catalysts for Asymmetric Organic Synthesis
Authors: Ni Bukuo , Headley Allan D.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Development of an Efficient Therapeutic Agent for Alzheimer′s Disease: Design and Synthesis of Dual Inhibitors of Acetylcholinesterase and Serotonin Transporter
Authors: Toda Narihiro , Kaneko Tsugio , Kogen Hiroshi
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective Organocatalytic Strecker Reactions in the Synthesis of α‐Amino Acids.
Authors: Martens Juergen
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oximes of Six‐Membered Heterocyclic Compounds with Two or Three Heteroatoms. Part 1. Synthesis and Structure.
Authors: Abele E. , Abele R. , Lukevics E.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dynamic Approaches Towards Catalyst Discovery
Authors: Gasparini Giulio , Dal Molin Marta , Prins Leonard J.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Dendrimers: A Mimic Natural Light‐Harvesting System
Authors: Zeng Yi , Li Ying‐Ying , Chen Jinping , Yang Guoqiang , Li Yi
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Near‐Infrared Organic Compounds and Emerging Applications
Authors: Qian Gang , Wang Zhi Yuan
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Progress of Catalytic Polymerization for Controlling Polymer Topology
Authors: Guan Zhibin
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition‐Metal‐Catalyzed Cycloadditions for the Synthesis of Eight‐Membered Carbocycles.
Authors: Yu Zhi‐Xiang , Wang Yi , Wang Yuanyuan
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses and Functional Properties of Phthalocyanines
Authors: Sakamoto Keiichi , Ohno‐Okumura Eiko
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Arsenic Chemistry
Authors: Henke Kevin R. , Hutchison Aaron
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Bicyclonucleosides Having a C—C Bridge
Authors: Lebreton Jacques , Escudier Jean‐Marc , Arzel Laurence , Len Christophe
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Synthesis of Heterocyclic‐Sugar Nucleoside Analogues
Authors: Romeo Giovanni , Chiacchio Ugo , Corsaro Antonino , Merino Pedro
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Five Years Patenting Time Frame Concerning Enzymatic Preparation of Glycosides
Authors: Trincone Antonio
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Unusual Isolated Precatalyst Systems Using TaniaPhos/MandyPhos Ligands
Authors: Briel Oliver , Doppiu Angelino , Karch Ralf , Le Ret Christophe , Winde Roland , Nass Andreas Rivas
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Progress in the Chemistry of Dihydropyrimidinones
Authors: Phucho I. T. , Nongpiur A. , Tumtin S. , Nongrum R. , Nongkhlaw R. L.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: s‐Tetrazines as Building Blocks for New Functional Molecules and Molecular Materials
Authors: Clavier Gilles , Audebert Pierre
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Applications. 10 Years of Experience in Monodentate, Bidentate, Tridentate, and Macrocycle Pyrazole Heterocyclic Chemistry
Authors: Rachid Touzani , Abdelkrim Ramdani , Sghir El Kadiri
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Catalysis of Diels—Alder Reaction
Authors: Du Haifeng , Ding Kuiling
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Computational Enzymology
Authors: Lonsdale Richard , Ranaghan Kara E. , Mulholland Adrian J.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Vaccinium myrtillus as an Antidiabetic Medicinal Plant — Research Through the Ages
Authors: Helmstaedter A. , Schuster N.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ultrafast Vibrational Dynamics and Local Interactions of Hydrated DNA
Authors: Szyc Lukasz , Yang Ming , Nibbering Erik T. J. , Elsaesser Thomas
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tackling Metal Regulation and Transport at the Single‐Molecule Level
Authors: Chen Peng , Andoy Nesha May , Benitez Jaime J. , Keller Aaron M. , Panda Debashis , Gao Feng
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Challenges of Determining Metal—Protein Affinities
Authors: Xiao Zhiguang , Wedd Anthony G.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: How Druggable Is Protein Kinase CK2?
Authors: Cozza Giorgio , Bortolato Andrea , Moro Stefano
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Integrating Reaction Chemistry into Molecular Electron Devices
Authors: Shen Qian , Guo Xuefeng , Steigerwald Michael L. , Nuckolls Colin
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Transfer Hydrogenation of Acetophenone Catalyzed by in situ Generated 2,6‐Bis(5‐thioxo‐4,5‐dihydro‐1,2,4‐triazole‐3‐yl)pyridine‐ruthenium(II) Complexes
Authors: CET?N Ahmet , DAYAN Osman
Published: July 2010

2,6‐Bis(5‐thioxo‐4,5‐dihydro‐1,2,4‐triazole‐3‐yl)pyridines (3, 4) were used for the first time as ligand in ruthenium catalyzed transfer hydrogenation of acetophenone. The in situ prepared three‐component system Ru(II)/tridentate triamine ligands (3a–3d, 4a–4d) and KOH catalysed the transfer hydrogenation reaction of acetophenone in good yields under mild conditions.
Inverse design of a phased‐array coil for breast magnetic resonance imaging
Authors: Li Yu , Liu Feng , Weber Ewald , Li Bing , Crozier Stuart
Published: July 2010

Breast magnetic resonance imaging (MRI) is a very useful tool for human breast cancer detection and the advance of dedicated RF coil technology is essential for enhanced image quality. In this work, we propose an efficient, hybrid algorithm for the inverse design of a phased array coil for breast MRI. The design method starts with the specification of the desired RF (B1) field within a predefined region, using the so‐called target‐field technique, followed by a streamline function method to find the initial coil winding by discretizing the calculated continuous current density. Then, a deformation approach is used to further optimize the coil shape by adjusting the coordinates of the selected control nodes on the coil contours; in this step, an iterative optimization algorithm is employed to minimize the cost functions that are mainly focused on the B1 homogeneity and coil inductance. A two‐element array breast coil has been designed using this method. The simulated and experimental results presented herein demonstrate the potential of the proposed design technique to produce low‐inductance coil structures with improved RF field. © 2009 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 35B: 221–231, 2009.
Digital multiband receiver for magnetic resonance
Authors: Sipilä Pekka , Schulte Rolf F. , Wachutka Gerhard , Wiesinger Florian
Published: July 2010

A multichannel, digital receiver made of off‐the‐shelf components is presented. The direct‐sampling and software‐based direct‐conversion constitutes a flexible receiver platform for multinuclear MR applications. The architecture allows increased level of flexibility in the functionality of the receiver, also beyond MR imaging and spectroscopy applications. The system is designed in a way that the parallel operation with a standard MRI scanner does not require either hardware changes or specially designed pulse sequences. By using proper anti‐alias filtering at the RF front‐end, the system described can be applied for signal detection up to 128 MHz, corresponding to 3 T proton MR. In comparison with a standard, clinical MRI receiver systems, the described receiver provides comparable signal‐to‐noise ratio but results in somewhat decreased data processing speed. The multichannel, multifrequency characteristics are exploited for magnetic field monitoring using 2H deuterium‐based NMR probes in conjunction with non‐Cartesian 1H proton signal detection. Furthermore, the wide bandwidth direct sampling scheme is demonstrated for simultaneous acquisition of multiple signals at distinct, nonoverlapping frequency bands. © 2009 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 35B: 210–220, 2009
Introduction: Charting the landscape of cancer survivors' health‐related outcomes and care
Authors: Pollack Lori A. , Rowland Julia H. , Crammer Corinne , Stefanek Michael
Published: July 2010

The field of cancer survivorship is characterized by a complex and rapidly evolving landscape. This supplement presents a series of data‐driven articles selected to highlight the breadth of new knowledge in this area of the cancer control continuum that were presented at the Fourth Biennial Cancer Survivorship Research Conference in Atlanta, Georgia, June 2008. Included in the volume is research on the biobehavioral impact of cancer; studies on quality‐of‐life and economic outcomes; and work focused on caregivers, understudied populations, and healthcare providers. Cancer 2009;115(18 suppl):4265–9. Published 2009 by the American Cancer Society.
Quality of life in a prospective cohort of elderly women with and without cancer
Authors: Lazovich DeAnn , Robien Kim , Cutler Gretchen , Virnig Beth , Sweeney Carol
Published: July 2010

BACKGROUND:

Quality of life (QOL) is an important issue for cancer survivors; few studies are able to consider elderly populations, address long‐term survival (≥5 years), examine different cancers, or include a valid noncancer comparison group.

METHODS:

The authors assessed QOL in 2004 among women participating in the Iowa Women's Health Study, a prospective cohort of older women followed since 1986. Cancer occurrence during follow‐up was identified through the State Health Registry of Iowa. The authors compared unadjusted, and age‐ and comorbidity‐adjusted mean scores for 8 Medical Outcomes Study 36‐Item Short‐Form Health Survey (SF‐36) scales among women with and without cancer by all cancer types, stage, and survival. Analyses were repeated after excluding women who developed a second primary cancer or reported cancer treatment in 2004.

RESULTS:

Among 17,385 respondents aged 71‐89 years, 2717 (16.6%) had been diagnosed with cancer since 1986. Compared with women without cancer, survivors fared worse on the General Health scale, regardless of cancer type (except colorectal), stage, or survival. Except for lower scores among the longest survivors, Mental Health scores did not differ significantly between women with and without cancer. Women with genitourinary, lung, hematopoietic, lymphoma, or other gastrointestinal cancers, with cancer at the distant stage, or who survived at least 10 years consistently experienced significantly lower QOL scores than cancer‐free women for most scales.

CONCLUSIONS:

Differences in QOL depended upon the specific SF‐36 scale and which aspect of cancer survivorship was examined. These findings underscore the complexity of factors contributing to QOL among cancer survivors. Cancer 2009;115(18 suppl):4283–97. © 2009 American Cancer Society.
Clinical practice guidelines for the psychosocial care of cancer survivors
Authors: Jacobsen Paul B.
Published: July 2010

Upon completion of their primary treatment, many cancer survivors become “lost in transition,” and receive inadequate or, at best, poorly coordinated follow‐up care. Unmet psychosocial and educational needs figure prominently among the concerns identified by survivors of adult‐onset cancers in the post‐treatment period. This article focuses on the role clinical practice guidelines could play in improving the quality of psychosocial care provided to these post‐treatment survivors. After defining clinical practice guidelines and describing their development, the article provides an overview of existing clinical practice guidelines for the psychosocial care of cancer patients and identifies their strengths and weaknesses. A major weakness relevant to this article is that none of the existing guidelines focus on the post‐treatment period. Two recent efforts in the field of cancer survivorship are identified that should stimulate and inform the development of guidelines for psychosocial care in the post‐treatment period. One effort is the growing movement to implement survivorship care planning at the end of primary treatment. Assessing and addressing unmet and anticipated psychosocial needs have been identified as major components of survivorship care planning. The other effort is the release by the Children's Oncology Group of Long‐term Follow‐up Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers. These guidelines provide a useful model of how guidelines for the psychosocial care of survivors of adult‐onset cancers might be developed, organized, and implemented. Cancer 2009;115(18 suppl):4419–29. © 2009 American Cancer Society.
An analysis of a multiple‐drug program in the treatment of patients with advanced breast cancer utilizing 5‐fluorouracil, cyclophosphamide, and prednisone with or without vincristine
Authors: Ahmann David L. , Bisel Harry F. , Hahn Richard G. , Eagan Robert T. , Edmonson John H. , Steinfeld Jesse L. , Tormey Douglass C. , Taylor William F.
Published: July 2010

Ninety patients with advanced breast cancer received a polychemotherapeutic program composed of 5‐fluorouracil, cyclophosphamide, and prednisone with or without vincristine as a control group in a series of four consecutive Phase II clinical trials of new drug programs. Objective regression rates were 59% without vincristine and 46% with vincristine. Projected mean length of regressions exceeds I year. Site of dominant disease, disease‐free interval, or performance scale score (if score was 0, 1, or 2, ECOG scale) failed to influence response rates; decreasing response rates were noted as the length of time increased after menopause. No advantage existed in patients experiencing severe myelosuppression (nadir leukocyte count of less than 1,500/mn3, and appreciable response rates occurred without significant myelosuppression. The addition of vincristine to the regimen failed to increase the response rates, and only increased toxicity. The program as outlined is reasonably tolerable and effective for this group of patients with advanced breast cancer.
Differential uptake of alkylating agents by normal and leukemic lymphocytes
Authors: Brody Jerome I.
Published: July 2010

When 14C‐labeled cyclophosphamide and nitrogen mustard were incubated separately with normal lymphocytes and lymphocytes from patients with chronic lymphocytic leukemia, the amount of radioactivity associated with the normal cells far exceeded that detected on the leukemic lymphocytes. This comparative diminution may be analogous to the impaired PHA response and excess surface immunoglobulin which serve as identifying markers of the malignant B cell. Cytotoxicity and neuraminidase experiments indicated that drug uptake by lymphocytes is not capricious and may occur in an optimum, predetermined fashion. Although surface uptake and therapeutic response are not necessarily directly interrelated, initial peripheral contact with an antineoplastic agent may be an essential step which modifies tumor sensitivity or resistance. Cancer 36:1959–1965, 1975
Unfavorable prognosis of acute leukemia in infancy
Authors: Cangir Ayten , George Stephen , Sullivan Margaret
Published: July 2010

Pretreatment characteristics of 48 infants (under 2 years of age) with leukemia treated over a period of 18 years at a single institution were studied in relation to response to therapy, extramedullary involvement, and survival. In order to provide a basis of comparison, 45 of the infants were each paired with an older (2–9 years of age) leukemic child, who had the same race, and disease type, who was treated within the same period of time and received similar suportive care and chemotherapy, and when possible, was of the same sex. The overall median survival times of infants and their pairmates were 211 days and 445 days, respectively. Initial status of the spleen was the single significant factor in relation to the length of survival. Median survival time for infants with splenomegaly was 186 days compared to a median survival time of 414 days for infants without splenomegaly. The complete response rate was 75% for infants and 80% for the pairmates. Median duration of remission was 84 days for infants and 280 days for their pairmates. Initial peripheral leucocyte count was significantly related to the duration of remission; patients with very high leucocyte counts had the shortest remissions. The duration of remission increased throughout the period covered by this study, however, prognosis relative to pairmates remained poor. Central nervous system leukemia occurred in 44% of infants and 40% of the pairmates; incidence of CNS leukemia was much higher (70%) in infants under one year of age than in infants one year old (37%). Extramedullary leukemia occurred at other sites in 46% of the infants and 31% of the pairmates. The only pretreatment characteristic of prognostic importance for predicting extramedullary involvement was the patient's age at diagnosis.
Cellular imunity in neoplasia: Antigen and mitogen responses in patients with bronchiogenic carcinoma
Authors: Rees John C. , Rossio Jeffrey L. , Wilson Henry E. , Minton John P. , Dodd Matthew C.
Published: July 2010

Cellular immune responses of patients with histologically confirmed lung carcinoma were assessed in vivo using cutaneous response and in vitro with a microlymphocyte blastogenic transformation (LBT) assay. In addition, correlation of the cutaneous response with the migration inhibitory factor (MIF) assay and LBT response was examined. The results indicated that cutaneous responses seen in patients with cancer of the lung were consistently lower than similar responses in normal controls (p < 0.001). Similarily, the percentage of positive cutaneous responses seen with patients included in this study was lower than the frequencies reported by others. Stimulation of cells from lung cancer patients by PHA‐M was also depressed when compared to similar lymphocytic responses in normal volunteers (p < 0.001). The correlation between cutaneous response to tuberculin and the in vitro assays was high. The few instances of disparity demonstrate the need to utilize more than one assay in evaluating cellular immune functions. These data would support the work of ther that indicate a depression of cellular immunity in advanced malignancy.
Adenocarcinoma of the small intestine arising in crohn's disease: Demonstration of a tumor‐associated antigen in invasive and intraepithelial components
Authors: Newman Robert D. , Bennett Sidney J. , Pascal Robert R.
Published: July 2010

A segment of small intestine surgically removed from a man with intestinal obstruction was found to have coexisting regional enteritis and an invasive adenocarcinoma associated with an area of intraepithelial neoplasia. The cells of the adenocarcinoma and the intraepithelial neoplasia contained a tumor‐associated surface antigen capable of reacting with an antiserum prepared against a colonic carcinoma. The importance of thorough sampling of specimens of regional enteritis in accurate reporting of the incidence of carcinoma is stressed, as is the use of immunohistologic techniques as an adjunct to the morphologic diagnosis of preinvasive neoplasia.
Primary malignant melanocytic tumors of the sympathetic ganglia, with an ultrastructural study of one
Authors: Fu Yao‐Shi , Kaye Gordon I. , Lattes Raffaele
Published: July 2010

Three cases of melanocytic tumors arising in the sympathetic chain were studied. A metastasis from one of them was studied with electron microscopy. Both light and electron microscopy demonstrated the presence in these tumors of true melanogenesis and autophagic activity in melanocytes as well as phagocytosis of mature melanin by associated histiocytes. Review of the embryology, biochemistry and in vitro culture of sympathetic nervous tissue showed a close relationship between it and pigmented cells in other parts of the body which are also derived from neural crest. These findings support the clinical and morphological conclusion that these rare pigmented tumors are true melanocytic tumors originating from the sympathetic chain. The malignant potential of these tumors is emphasized by the fact that the two patients who survived initial surgery later died of metastatic disease.
The urinary excretion of corticosteroid sulfates by cancer patients
Authors: Rose D. P. , Fahl W. E. , Liskowski L.
Published: July 2010

Urinary excretions of free cortisol and corticosteroid sulfates were determined in 31 female controls, 77 breast cancer patients, 14 cases of colonic cancer, and 7 patients with bronchial carcinoma. Elevated corticosteroid sulfate excretion was present in38% of patients with locally recurrent breast cancer and 30% of those with distant metastases, but in only 13% of the “early” breast cancer cases. A similar abnormality was seen in colonic cancer. Urinary free cortisol was usually normal. ACTH stimulation in a normal subject produced marked increases of both urinary free cortisol and corticosteroid sulfates. It is concluded that elevated corticosteroid sulfate excretion in cancer patients arises from an increased cortisol production rate combined with increased sulfurylation of the steroid. In bronchial carcinoma patients, changes similar to those occurring in the ACTH–treated normal subject may have resulted from ectopic ACTH production in the tumor.
Clinical evaluation of a method of quantitative determination of homovanillic acid for the estimation of degree of tumor dissemination process in melanoma of the skin
Authors: Trapeznikov N. N. , Raushenbakh M. O. , Ivanova V. D. , Yavorsky V. V.
Published: July 2010

Homovanillic acid (HVA) was determined both in 45 patients with different forms of melanoma and those hospitalized on the suspicion of melanoma and in 15 healthy persons. Excretion rate of homovanillic acid within the normal limits was observed in patients with benign melanotic neoplasms of the skin (4.4 ± 0.56 mg/24 hr) and in local forms of melanotic melanoma of the skin (4.5 ± 0.24 mg/24 hr). In patients with metastases to regional nodes as well as in patients with locally disseminated forms of melanotic melanoma of the skin the concentration of homovanillic acid increased up to 11.1 ± 0.93 mg/24 hr. Especially strong concentration of homovanillic acid was registered in patients with disse minated melanotic melanoma of the skin, and it made up 15.7 ± 2.04 mg/24 hr. There was evident tendency to the elevation of HVA excretion level as generalization of the process which was taking place. The data obtained enable the authors to recommend the determination of HVA excretion as an additional diagnostic test as well for prognosis of melanoma development together with other clinicomorphological data.
Hodgkin's disease in the bone marrow
Authors: Weiss Raymond B. , Brunning Richard D. , Kennedy B. J.
Published: July 2010

Tumor involvement of the bone marrow in patients with Hodgkin's disease may be suspected in the presence of other manifestations of advanced disease such as fever, lymphopenia, hypoalbuminemia, mixed cellular histologic type, or Stage III or IV disease by other clinical parameters. It occurs more frequently in the older age groups. When anemia, leucopenia, and/or thrombocytopenia are present and are unrelated to recent bone marrow suppressant chemotherapy, marrow involvement is likely to be present. Bone marrow examination, done by multiple trephine biopsies, provides an adequate sampling of tissue and results in a high incidence of detection of involvement by Hodgkin's disease. This manifestation of Hodgkin's disease is associated with a relatively short survival. Aggressive combination chemotherapy is necessary to produce a significant remission.
Primary malignant fibrous histiocytoma of bone
Authors: Spanier Suzanne S. , Enneking William F. , Enriquez Pablo
Published: July 2010

A review of over 400 primary bone tumors yielded 11 lesions with features allowing classification as malignant fibrous histiocytoma on a purely histological basis. Correlation with roentgenograms and clinical data indicated that these tumors occurred as osteolytic lesions associated with a high incidence of pathologic fractures in the metaphyses of skeletally mature long bones. Nine patients developed pulmonary metastases and 3 developed lymph node metastases within 21 months following diagnosis. The average survival was 12 months in 6 of the 9 patients who had no secondary treatment of their metastases. Treatment of 3 patients with metastatic lesions with chemotherapy or radiotherapy has been clinically encouraging. Some evidence was obtained that either or both the histiocytic and fibroblastic component may metastasize. There is a need for biopsy of metastatic lesions and autopsy followup to more accurately assess the mode of spread and histologic type of the metastases.
Hodgkin's disease in childhood
Authors: Norris Donald G. , Burgert E. Omer , Cooper Herbert A. , Harrison Edgar G.
Published: July 2010

A retrospective study of 116 children with Hodgkin's disease diagnosed in the period 1935–1970 was undertaken to assess the prognostic role of histopathologic classification and clinical extent of the disease. The ages of the 80 boys and 36 girls ranged from 2.5 years to 15.0 years (mean, 10.0 years). The histopathologic diagnosis by lymph node biopsy revealed lymphocyte predominance in 22, nodular sclerosis in 67, mixed cellularity in 24, and lymphocyte depletion in 3. Within the subgroup of nodular sclerosis, 47 biopsies had classic well‐developed collagenous bands, whereas 20 were in the cellular phase (10 without collagenous bands and 10 with minimal collagen). The clinical extent of disease was determined. There were 33 patients with Stage I disease, 38 with Stage IIA, 12 with Stage IIB, 24 with Stage III, and 9 with Stage IV. Survival correlated with histopathologic type and clinical stage, but not with age or sex. Survival was not dependent on the degree of collagenization in nodular sclerosis. There were 29 patients who survived for more than 10 years. Four of these 29 subsequently died owing to acute myelomonocytic leukemia, carcinoma of the breast, sepsis, and progression of Hodgkin's disease, respectively. Neoplasms developed in two other long‐term survivors (thyroid carcinoma in one, and multiple basal cell carcinomas in the other).