bluuebunny/crossref_metadata_2025 huggingface dataset:
Conhecimento, atitudes e práticas de adolescentes e pais sobre imunização na adolescência: revisão sistemática
Authors: Peixoto Alisse Maria Chaves de Lima , Valença Paula Andréa de Melo , Amorim Viviane Colares Soares de Andrade
Published: October 2018

Objetivo: Descrever os fatores associados aos conhecimentos, atitudes e práticas de adolescentes e seus pais frente à imunização na adolescência. Métodos: Revisão sistemática da literatura, realizada nos meses de março de 2017 a março de 2018, por meio de três estratégias de busca no Portal CAPES e BVS, através dos descritores: adolescente; imunização; conhecimentos; atitudes e práticas em saúde; vacinação e controle de doenças transmissíveis. Os critérios de elegibilidade utilizados foram: artigos científicos publicados nos idiomas inglês, português e espanhol, nos anos de 2008 a 2018. Após as buscas, incluíram-se 23 artigos na análise final. Resultados: Verificaram-se os seguintes fatores diretamente associados à imunização na adolescência: sexo; religião; raça/etnia; idade, local de residência; crenças sobre a eficácia e segurança da vacina; medo dos efeitos adversos; possuir convênio privado de saúde e recomendação pelos profissionais de saúde. No Brasil, alguns fatores diferem dos outros países, como a maior vacinação contra o HPV entre as meninas e contra a Hepatite B entre aqueles com menor renda per capita. Isto pode ser explicado porque o Brasil tem uma realidade econômica, social e um sistema de saúde diferente do que se observa nos demais países. Conclusão: Fatores sociodemográficos como sexo, raça/etnia, religião e idade foram associados ao conhecimento, atitudes e práticas acerca da imunização na adolescência. Fatores socioeconômicos e psicossociais, como insegurança, medo, preocupações com o custo da vacina, ter recebido recomendação e orientação sobre vacinação por um profissional de saúde também demonstraram associação.
El arquetipo de viaje en el cine moderno de terror: la historia de una subversión.
Authors: Alés Fernández Rocío
Published: October 2018

La propia historia fundacional de Estados Unidos, que sienta sus bases sobre el viaje que los puritanos ingleses realizaron en el siglo XVII en busca de una nueva Jerusalén, explica el lugar de referencia que el arquetipo del viaje ostenta en el imaginario cultural de este país. A lo largo del siglo XIX y principios del XX, la literatura estadounidense centraría gran parte de sus argumentos en el viaje figurado y metafórico, al igual que muchos de los géneros del Hollywood clásico y genuinamente norteamericanos como el western. Con el paso del tiempo, en el contexto de la crisis política, social y cultural que atravesarían los Estados Unidos a finales de la década de los sesenta, el cine moderno de terror se apropiaría de este arquetipo para llevar a cabo la definitiva subversión del mismo. En el siguiente artículo profundizaremos sobre la importancia del arquetipo del viaje en el imaginario cultural estadounidense y su posterior fractura en momentos de crisis social, a través del estudio de su evolución en la literatura y los géneros cinematográficos.
Los entresijos de la mirada: una propuesta metodológica para analizar la praxis fílmica
Authors: Galindo Pérez Jose María
Published: October 2018

A la hora de reflexionar sobre la praxis fílmica resulta imprescindible detener la mirada en una pregunta clave: ¿cómo obtener un conocimiento mayor y mejor sobre el proceso por el cual se hacen las películas? El presente artículo adopta como objeto de estudio la metodología de análisis que puede conducir a ese saber más amplio y más profundo. El diseño de esa metodología y su posterior desarrollo se articulan sobre las siguientes líneas de actuación: la identificación de los obstáculos que dificultan el acceso al conocimiento sobre la praxis fílmica; la construcción ideológica y operativa de los instrumentos de análisis; y la puesta a punto de la metodología analítica al entrar en contacto con un caso de estudio concreto. El encuentro entre la antropología y los estudios fílmicos se revela como una interesante manera de investigar una práctica tradicionalmente oculta tras numerosos mitos.
ESTUDO FÍSICO-QUÍMICO DE XAROPE BRONCODILATADOR ADULTO
Authors: LOPES Anna Caroline , MORAES Amanda De , OLIVEIRA Ana Flávia Reda de , GUIMARÃES Bianca Pontes , OLIVEIRA Camila Freitas de , BETIM Fernando César Martins , MARTINEZ Amanda Lyra , BOBEK Vanessa Barbosa
Published: October 2018

Xaropes são preparações farmacêuticas aquosas, geralmente compostas por açúcar, nas quais são incluídos fármacos para fabricação e comercialização de medicamentos. O objetivo deste trabalho foi comparar as diferentes apresentações do xarope broncodilatador Acebrofilina, analisando as características físico-químicas do medicamento de referência, similar e genérico. Os testes físico-químicos realizados foram: densidade através do método da picnometria, viscosidade pelo método do viscosímetro Oswald e verificação do pH com o auxílio de um peagâmetro digital. O medicamento de referência foi o que apresentou maior densidade (1,23 g/cm3) e maior viscosidade (44,5372 Poise). Foram observadas diferenças nos valores das amostras, houve variação de densidade e viscosidade e uma sutil diferença de pH, esta diferença pode estar relacionada com a qualidade dos métodos de fabricação e matéria-prima.
ANÁLISE FÍSICO-QUIMICA COMPARATIVA DE SABONETES LÍQUIDOS
Authors: LOPES Anna Caroline , MORAES Amanda De , OLIVEIRA Ana Flávia Reda de , GUIMARÃES Bianca Pontes , OLIVEIRA Camila Freitas de , BETIM Fernando César Martins , MARTINEZ Amanda Lyra , BOBEK Vanessa Barbosa
Published: October 2018

O presente trabalho teve como objetivo realizar testes físico-químicos de duas amostras de sabonete líquido diferentes, a fim de compará-las. As análises foram realizadas no laboratório de química das Faculdades Ponta Grossa (FacPG) e no laboratório de produção de medicamentos (LAPMED) da Universidade Estadual de Ponta Grossa (UEPG). Os parâmetros físico-químicos analisados foram: densidade através do método da picnometria, viscosidade pelo método do viscosímetro rotacional (Brookfield) e verificação do pH com o auxílio de um peagâmetro digital. As análises das amostras A e B foram realizadas em triplicatas e os resultados obtidos foram comparados com a literatura. Os valores de densidade encontrados foram 1,003 g/cm 3 para a amostra A e 0,6207 g/cm 3 para a amostra B. Os valores de pH e viscosidade encontrados foram, respectivamente 5,76, 6RPM/s 10,69Pa.s, 12RPM/s 8,28Pa.s para a amostra A, e 6,56, 6RPM/s 4,68Pa.s, 12RPM/s 3,59Pa.s para a amostra B. Com a realização das análises físico-químicas pode ser observado uma diferença significativa entre as amostras, sendo a amostra A mais densa, mais viscosa e com o pH mais ácido que a amostra B.
RELAÇÃO ENTRE VARIÁVEIS CLIMÁTICAS E MORTALIDADE POR DOENÇAS DO APARELHO CIRCULATÓRIO EM IDOSOS NO MUNICÍPIO DE PARANAVAÍ – PR
Authors: FERNANDES Vinicius , LEITE Maysa De Lima
Published: October 2018

Introdução: a mortalidade por doenças do aparelho circulatório e sua relação com o meio ambiente têm sido alvo de estudos ao longo dos anos. Sendo assim, o clima pode influenciar negativamente a saúde dos indivíduos de determinadas populações mais vulneráveis como os idosos. Objetivo: análise da relação das variáveis climáticas sobre as doenças do sistema circulatório associado aos idosos de um município do Paraná. Método: estudo transversal entre os anos 1998 a 2014 contemplando idosos do município de Paranavaí-PR com dados coletados a partir do Departamento de Informática do Sistema Único de Saúde (DATASUS). Comparou-se a taxa de mortalidade junto às variáveis climáticas: temperaturas médias e pluviosidade obtidos do Instituto Agronômico do Paraná (IAPAR). Efetuou-se para tanto, tabulação dos dados e confecção de gráficos para interpretação dos mesmos. Resultados e Discussão: as taxas de mortalidade a despeito das doenças cerebrovasculares se mostraram inversamente proporcionais às temperaturas médias e à pluviosidade em sua maioria, relação que se manteve semelhante para as demais doenças (isquêmicas, hipertensivas e outras). Além disso, a idade elevada firmou-se como um pilar para os efeitos deletérios do meio ambiente sobre a saúde dessa população que por vezes se mostra mais vulnerável com o decorrer dos anos. Considerações finais: as associações demonstradas no estudo denotam a fragilidade do grupo de idosos da cidade em específico em relação às condições climáticas estudadas.
AVALIAÇÃO DOS EFEITOS TÓXICOS DO AGROQUÍMICO TORDON® SOBRE OS ORGANISMOS TESTE Lactuca sativa E Allium cepa.
Authors: MARTINS Hugo , CAMPOS PEREIRA Franco Dani
Published: October 2018

O uso de agroquímicos na agricultura geram diversos danos ao meio ambiente, e a contaminação por essas substâncias podem representar sérios riscos à saúde humana e a de outros organismos não alvo. Diante disso, o objetivo deste trabalho foi analisar os efeitos do herbicida Tordon sobre os parâmetros de fitotoxicidade em Latuca Sativa e sobre os parâmetros de genotóxicidade e mutagênicidade em células meristemáticas de Allium cepa expostas a diferentes concentrações da substância obtidas por diluições seriadas. Foram analisadas concentrações (Controle Negativo, Controle Positivo, 100% (substância pura), 10%, 1%, 0,1%, 0,01%, 0,001%, 0,0001%, 0,00001% e 0,000001%). Os resultados demostraram efeitos genotóxicos e mutagênicos para as maiores concentrações revelando uma curva dose resposta, onde as menores concentrações avaliadas apresentaram os menores índices de toxicidade. Mais estudos devem ser realizados uma vez que este ainda é um estudo preliminar.
PREPARO DE PADRÃO SECUNDÁRIO PARA IDENTIFICAÇÃO DE CLORIDRATO DE TRAMADOL
Authors: KLOTH Paula Caroline , HENKE Aline Tavares , GABRIEL Maria Madalena , WAGNER Ricardo
Published: October 2018

RESUMO: O medicamento cloridrato de tramadol, apresenta diversos problemas sociais devido a sua possível toxicidade e potencial de abuso quando utilizado por períodos longos. Desta maneira, para a detecção dessa substância em líquidos biológicos os laboratórios necessitam utilizar padrões de identificação. Muitas vezes esses padrões apresentam um custo elevado e são de difícil obtenção. Em vista a essas dificuldades, o presente trabalho teve como objetivo o desenvolvimento de um padrão secundário a partir de um medicamento doado ao laboratório de Toxicologia da UFPR. Para o desenvolvimento, a substância cloridrato de tramadol foi extraída a partir de 8 comprimidos de Tramal Retard® de 100 mg (Pfizer). Como resultado da extração, obteve-se um rendimento de 89,37%. A substância extraída apresentou um pico de absorção característico no espectro de absorção ultravioleta em 275nm. A análise por CLAE-FLD mostrou apenas um pico único nas condições analíticas utilizadas.  O teor determinado por titulação com ácido perclórico foi de 94,39%. O padrão secundário obtido foi aplicado em uma análise qualitativa por cromatografia em camada delgada frente a uma urina sabidamente positiva para uso de tramadol e apresentou Rf de 0,77, comparável ao tramadol encontrado na urina. Por fim, conclui-se que o padrão desenvolvido está apto para ser utilizado na rotina para métodos de triagem na identificação do cloridrato de tramadol em aulas práticas de Toxicologia.
Ações de Educação Ambiental em Escolas de Ensino Fundamental e Médio do Município de Alegre-ES
Authors: Da Silva Martins Camila Aparecida , Guimarães Damaris , Scaramussa Gonçalves Morgana , Oliveira Nogueira Natiélia , Dos Santos Azevedo Cássia , Da Silva Chansislayne Gabriela , Elias de Oliveira Juliana
Published: October 2018

Resumo: A educação ambiental deve ser considerada como um dos mais importantes instrumentos de trabalho a ser utilizado na formação de cidadãos conscientes sobre problemas de ordem ambiental, social e econômica que ocorrem no país. Nesse contexto, o objetivo deste trabalho foi desenvolver ações de educação ambiental com base em conhecimentos técnico-científicos da área de Ciências Agrárias e de ciências afins, para conscientizar os alunos da rede pública de ensino fundamental e médio do município de Alegre-ES sobre a importância da preservação ambiental. O trabalho foi desenvolvido por meio de pesquisa exploratória em livros, periódicos e sites para compor a revisão bibliográfica e subsidiar a realização de visitas periódicas nas escolas participantes do projeto para definir, organizar, planejar e desenvolver as seguintes ações de educação ambiental: estudo de caso; oficinas sobre confecção de brinquedos e de horta vertical com a reutilização de material reciclável, teatros, gincanas, palestras, distribuição de panfletos e instalação de exemplares de horta vertical. De acordo com a receptividade, o interesse, a participação e o retorno observado nas comunidades escolares atendidas, pode-se afirmar que as ações de educação ambiental desenvolvidas foram importantes para (i) conscientizar, sensibilizar e mobilizar as pessoas envolvidas no projeto sobre a importância da preservação ambiental; (ii) estimular o envolvimento de alunos e professores na execução de atividades educativas diferenciadas sobre questões ambientais.
Agrotóxicos e Transgênicos: Uma Crítica Popular
Authors: Ramos Rodrigo Ferraz , Andrioli Antônio Inácio , Betemps Débora Leitzke
Published: October 2018

Diversas críticas foram inferidas contra a revolução verde e sua variante denominada revolução duplamente verde. A primeira introduziu o uso de agrotóxicos e, a segunda, os transgênicos na agricultura. Apesar do movimento estudantil da agronomia corroborar com a discussão acerca da temática dos agrotóxicos e transgênicos, são escassos os trabalhos na literatura científica que abordem as contribuições do movimento estudantil nas discussões dessa temática. Por isso, objetivou-se abordar o debate acerca dos agrotóxicos e transgênicos na perspectiva do movimento estudantil nacional da agronomia. Realizou-se uma revisão bibliográfica acerca da temática e posteriormente, conduziu-se uma análise sobre o posicionamento da militância da Federação de Estudantes de Agronomia do Brasil (FEAB) acerca do tema proposto. Observou-se que o movimento estudantil nacional da agronomia conduz diversas iniciativas em prol da ampliação da discussão acerca dos riscos do uso dos agrotóxicos e as incertezas do uso de transgênicos na agricultura. Conclui-se que as iniciativas do movimento estudantil nacional estão em defesa de uma agricultura sustentável.
DIAGNÓSTICO DOS RESÍDUOS SÓLIDOS DOMICILIARES GERADOS NO MUNICÍPIO DE CAMPO MAGRO – PR, BRASIL
Authors: Strapação Sidnei , Martins Sandra Regina , Silva Cesar Aparecido da
Published: October 2018

Os resíduos sólidos têm se tornado um desafio para os gestores municipais por constituírem-se um risco à saúde pública e aos ecossistemas. Este trabalho teve como objetivo realizar um diagnóstico da situação da coleta, acondicionamento e disposição final dos resíduos sólidos domiciliares do município de Campo Magro, situado no Estado do Paraná, na região metropolitana de Curitiba, através de entrevista com o gestor municipal e análises de documentos fornecidos pela prefeitura da cidade. Constatou-se que a coleta, tanto a área urbana quanto a rural, atende 100% da população e que os resíduos são dispostos no aterro consorciado que atende a grande Curitiba, sendo que os recicláveis são direcionados para uma cooperativa especializada gerando renda para seus participantes. No entanto, ainda é preciso ações para diminuir a geração de resíduos através de campanhas de conscientização para os munícipes.
The Effect of Length of Stay and Discharge Disposition on Hospital Consumer Assessment of Healthcare Providers and Systems Scores in Orthopaedic Patients
Authors: Shulman Brandon , Hutzler Lorraine , Karia Raj , Bosco Joseph
Published: October 2018

Background:

The study assesses whether Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores were influenced by hospital length of stay (LOS) and discharge disposition.

Methods:

HCAHPS scores from 5,682 orthopaedic patients were collected over a 4-year period. Statistical analyses were run to identify associations between Top-Box scores for each HCAHPS domain and LOS or discharge disposition (home versus rehabilitation facility).

Results:

Decreased LOS was associated with increased HCAHPS Top-Box scores for every Top-Box domain except for Discharge composite (P ≤ 0.001 to 0.011). Discharge to home was associated with increased HCAHPS scores for four Top-Box domains (P ≤ 0.001 to 0.009).

Discussion:

Shorter LOS and discharge to home after orthopaedic surgery are associated with better HCAHPS scores. Earlier discharge leads to an improved patient-reported experience and can increase reimbursements. Expedient, appropriate discharge of hospitalized orthopaedic patients should be a treatment goal after orthopaedic surgery.
Software Effort Estimation Risk Management over Projects Portfolio
Authors: KOUTBI Salma EL , IDRI Ali
Published: October 2018

Over the last decades, software development effort estimation has integrated new approaches dealing with uncertainty. However, effort estimates are still plagued with errors limiting their reliability. Thus, estimates error management at an organization level provides a promising alternative to the classical approaches dealing with single projects as a portfolio can afford more flexibility and opportunities in terms of risk management. The most widely used approaches in risk management were mainly based on the Gaussian approximation that shows its limits facing “ruin” risk associated to unusual events. The aim of this paper is to propose a Multi-Projects Error Modeling framework to characterize error at a portfolio level using bootstrapping, mixture of Gaussians and power law to emphasize the tail behavior respectively.
Web Services Composition Using Dynamic Classification and Simulated Annealing
Authors: AlHadid Issam , Abu-Taieh Evon
Published: October 2018

Service Oriented Architecture (SOA) introduced the web services as distributed computing components that can be independently deployed and invoked by other services or software to provide simple or complex tasks. In this paper we propose a novel approach to solve the problem of the business processes execution engine web service selection and services composition in the Service Oriented Architecture (SOA) related to the Synchronous mode.  The paper provides a mechanism to improve the web services selection and service composition, using dynamic web services and service composition classification and Simulated Annealing (SA) to satisfy services' requirements expressed as the Service Level Agreement (SLA). The results show that the proposed approach enhanced the services composition by increasing the availability and decreasing the response time to the service composite.
Modernisering van de beklagregeling ex artikel 12 Sv: ‘Full dress’ voor het slachtoffer?
Authors: Kool R.S.B.
Published: October 2018

Modernisering van de beklagregeling ex artikel 12 Sv: ‘Full dress’ voor het slachtoffer?

Met de invoering van de Wet Versterking Slachtoffers (VPS, 2010) hebben slachtoffers rechten gekregen waarmee zij inbreng kunnen hebben in het vooronderzoek. Daarnaast hebben zij de mogelijkheid om bij het uitblijven van vervolging of opsporing een klaagschrift in te dienen bij het hof in het kader van de artikel 12 Sv-procedure. Het voornemen van de minister is deze regeling te verruimen, onder andere om de staande jurisprudentie te codificeren. Hoewel de verruiming inhoudelijk bijval verdient, is nog onvoldoende sprake van een systematisch op elkaar betrekken van de klachtprocedure en de procespositie van het slachtoffer als belanghebbende bij het vooronderzoek. Handvatten daartoe kunnen worden ontleend aan het project Strafvordering 2001.
Some new Gauss-Jacobi and Hermite-Hadamard type inequalities concerning $(n+1)$-differentiable generalized $((h_{1},h_{2});(\eta_{1},\eta_{2}))$-convex mappings
Authors: Kashuri Artion , Liko Rozana , Dragomir Silvestru Sever
Published: October 2018

In this article, we first introduced a new class of generalized $((h_{1},h_{2});(\eta_{1},\eta_{2}))$-convex mappings and two interesting lemmas regarding Gauss-Jacobi and\\ Hermite-Hadamard type integral inequalities. By using the notion of generalized\\ $((h_{1},h_{2});(\eta_{1},\eta_{2}))$-convexity and the first lemma as an auxiliary result, some new estimates with respect to Gauss-Jacobi type integral inequalities are established. Also, using the second lemma, some new estimates with respect to Hermite-Hadamard type integral inequalities via Caputo $k$-fractional derivatives are obtained. It is pointed out that some new special cases can be deduced from main results of the article.
Chest X ray Score (Timika Score): An Useful Adjunct to Predict Treatment Outcome in Tuberculosis
Authors: Chakraborthy Anushree , Shivananjaiah Akshata , Ramaswamy Swapna , Chikkavenkatappa Nagaraja
Published: October 2018

Introduction: Chest X-ray (CXR) has been used since long as an aid in the diagnosis of pulmonary tuberculosis (PTB) and also to determine the extent of the disease. The present study was conducted to evaluate the correlation of disease extent on CXR based on the Timika CXR score with clinical and microbiological parameters at baseline, in sputum positive cases of pulmonary tuberculosis. Material and methods: The study was conducted at a tertiary referral centre for chest diseases in Bangalore, Karnataka from January 2017 to January 2018. This is a prospective study of new sputum smear positive pulmonary tuberculosis cases diagnosed in the Department of Pulmonary Medicine. At baseline, patients’ symptoms and signs on chest auscultation were recorded. The clinical scoring was done by the Karnofsky performance score (KPS) and TB score I (Bandim TB score) and II. Baseline CXR postero-anterior (PA) view of each patient was assessed independently by two chest physicians and evaluated by the Timika CXR scoring method. Routine blood investigations and sputum smear for acid fast bacilli were done. The correlation between the CXR score and other disease severity parameters was analysed. Results: Clinical scores such as the KPS and TB score I and II, did not correlate with the presence of cavitary disease on CXR (p > 0.05). 48.6% of patients with cavitary disease had higher baseline AFB density in sputum (i.e. sputum smear microscopy grade 3+) as compared to 40% of patients with non cavitary disease, which was not statistically significant. CXR score > 71 was significantly associated with longer duration of symptoms, higher clinical scores (KPS and TB score I, II) and lower Body Mass Index (BMI) at diagnosis of PTB (p < 0.05). 65.2% of the patients with CXR score > 71 had significantly higher baseline AFB density as compared to only 32.4% with CXR score ≤ 71 (p < 0.04). CXR score > 71 also had significant association with higher ESR. Conclusion: Cavitary disease on CXR is associated with a higher mycobacterial load at baseline. The Timika CXR score is a simple, standard scoring system which can be used by a chest physician in a clinical setting. The CXR score significantly correlates with a broad range of clinical and microbiological measures of disease severity in PTB patients. Thus, it has a role in risk stratification, especially in patients not producing sputum or sputum negative PTB at diagnosis.
The Concurrence of Granulomatous Inflammation in Intrathoracic Lymph Nodes with Regional Metastasis from Primary Lung Cancer in Surgically Resected Specimens
Authors: Krvavac Armin , Munzer Kurt , Miller Aaron , Poddar Nishant , Jamkhana Zafar , Patolia Setu
Published: October 2018

Introduction: Granulomatous inflammation has been associated with malignancies such as breast, testicular, renal cell, and lymphoma. The coexistence of granulomatous inflammation in mediastinal/hilar lymph node with primary lung malignancy has been described in Case Reports. Our goal was to examine the frequency of granulomatous reaction in mediastinal/hilar lymph node in the patients who had undergone surgical resection of lung cancer. Material and methods: We performed a retrospective analysis of 40 patients (1) aged ≥ 18 years and (2) who underwent lobectomy or pneumonectomy from 1 August 2012 to 31 October 2016 at Saint Louis University Hospital and (3) had pathology suggestive of cancer. Results: Of those 40 patients, 3 (7.5%) had granulomatous inflammation in the lymph nodes. None of these 3 individuals had evidence of metastasis in the particular lymph nodes with granulomatous inflammation. Conclusion: Our small cohort revealed that the presence of granulomatous inflammation in a lymph node can be safely taken as an evidence of the absence of metastasis to the lymph node. This finding can obviate the need for further sampling for the particular lymph node with granulomatous inflammation and can decrease the sampling time.
The Effectiveness of Bronchial Artery Embolisation in Patients with Haemoptysis
Authors: Springer Daria , Cofta Szczepan , Juszkat Robert , Żabicki Bartosz , Goździk-Spychalska Joanna , Nowicka Agata , Winiarska Hanna , Batura-Gabryel Halina
Published: October 2018

Introduction: Bronchial artery embolisation (BAE) is one of the methods used in massive and recurring haemoptysis. The aim of the study is to determine the effectiveness and complications of bronchial artery embolisation in recurring haemoptysis. Material and methods: The analysis included 47 embolisation procedures performed on 30 patients treated between 2011 and 2017 in the Department of Respiratory Medicine, Allergology and Pulmonary Oncology due to haemoptysis. The patient’s age ranged between 18 and 71 years, while mean age at the time of BAE was 33.5 years. Patients with tuberculosis constituted 73.33% (n = 22) of the sample and underwent 31 embolisation procedures in total. The remaining part of the sample (n = 8) collectively underwent 16 BAEs. The analysis was conducted by verifying the medical documentation, as well as carrying face-to-face and phone conversations. Results: Immediate control due to the inhibition of bleeding was obtained in 95.75% of cases. Recurrence within 3 days of BAE was reported in 5 patients (10.63%), and 4 re-embolisation procedures were conducted. In 10 patients (33.33%), recurrence was observed during the first year post-BAE, while it was reported in 17 cases during the whole observation period (56.66% of patients). The subjects who underwent re-embolisation demonstrated recurrence-free periods lasting from 2 days to 63 months. In patients with recurrence but no re-embolisation, the shortest and longest haemoptysis-free time was 2 and 35 months, respectively. 11 patients (36.66%) required several embolisation procedures during the whole observation period. Conclusions: BAE is a highly successful procedure in treating haemoptysis. The risk of complications is low.
Lung Transplantation as a Viable Option of Treatment for Pulmonary Veno-Occlusive Disease
Authors: Ochman Marek , Urlik Maciej , Tatoj Zofia , Wajda-Pokrontka Marta , Zawadzki Fryderyk , Latos Magdalena , Zembala Marian
Published: October 2018

Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by alteration of pulmonary veins. Many clinical and hemodynamic similarities to idiopathic pulmonary arterial hypertension (IPAH) may cause diagnostic and therapeutic difficulties. This case report is about a patient with PVOD, whose first symptoms of the disease occurred after infectious mononucleosis. The patient was administered prostacycline (PGI2) mimetic (Treprostinil), which made qualification process and lung transplantation possible. Despite more and more knowledge about the causes, ethiopathogenesis and changes in pulmonary veins on molecular level, lung transplantation is the only successful therapeutic option for patients suffering from PVOD.
WSPÓŁCZESNA EKONOMIKA BEZPIECZEŃSTWA– RELACJE MIĘDZY EKONOMIKĄ A BEZPIECZEŃSTWEM
Authors: OZIĘBŁO Małgorzata
Published: October 2018

Artykuł wychodzi naprzeciw oczekiwaniom czytelnikom, którzy pragną pogłębić wiedzę ma temat zagadnień związanych z kwestią współczesnych problemów związanych z ekonomiką bezpieczeństwa. Celem artykułu jest ułatwienie odbiorcy zrozumienia aktualnych problemów związanych z ekonomiką bezpieczeństwa w ciągle zmieniającym się w XXI wieku świecie oraz zaprezentowanie ekonomiki bezpieczeństwa jako dyscypliny naukowej. W tekście przybliżono istotę, pojęcie, obiekt i przedmiot omawianej dyscypliny naukowej. Studium literatury tematu badań dowodzi, że problemy te nie zostały wystarczająco zbadane.
MODELOWANIE I SYMULACJA PROCESÓW EWAKUACJI Z WYKORZYSTANIEM OPROGRAMOWANIA FLEXSIM – STUDIUM PRZYPADKU
Authors: JURCZYK Krzysztof , CEMPEL Witold Aleksander
Published: October 2018

Symulacja komputerowa stanowi doskonałe narzędzie służące analizie złożonych procesów. Znajduje zastosowanie w sytuacjach, gdy zawodzą dostępne metody analityczne jednocześnie dostarczając jak największej liczby informacji o analizowanym procesie. W niniejszym artykule wykazano możliwość zastosowania oprogramowania do symulacji procesów dyskretnych FlexSim w weryfikacji przyjętych założeń dotyczących sposobu przeprowadzania ewakuacji budynku Szkoły Podstawowej im. Św. Kingi w Podstolicach. Celem badań było wykazanie możliwości ewakuacji osób przebywających na terenie placówki w zadanym czasie.
FILOZOFICZNO-MORALNA INTERPRETACJA WYBRANYCH HIPOTEZ LOGISTYKI
Authors: ADAMKIEWICZ Marek
Published: October 2018

W artykule dokonano metodologicznej analizy hipotez wyróżnionych przez filozofię nauki, które mogą być stosowane w logistyce. Zdefiniowano samo pojęcie hipotezy i jej kontrasty, jak też podjęto próbę skonstruowania dla logistyki przypuszczeń obecnych w metodologii wiedzy. Analizowano zatem charakter hipotezy dyrektywnej, przewidywania probabilistyczne oraz hipotezy deterministyczne i implikacyjne. Na tym tle poszukiwano związków pomiędzy możliwymi w logistyce przypuszczeniami a problemami mającymi zastosowanie w filozofii moralności.
ZNACZENIE NAUKI W BUDOWANIU ZDOLNOŚCI OPERACYJNYCH SIŁ ZBROJNYCH
Authors: DZIEDZIC Jan
Published: October 2018

W artykule przedstawiono problematykę związaną ze znaczeniem nauki w budowaniu zdolności operacyjnych sil zbrojnych z perspektywy ich składowych i relacji zachodzących między nimi. Wskazano na problematykę różnic w podejściu do budowania zdolności operacyjnych w odniesieniu do modelu przedmiotowego i zdolnościowego w aktualnym rozumieniu tego problemu. W podsumowaniu wskazano na możliwe obszary pogłębienia współpracy między nauką i pozostałymi „składowymi triady”, a więc przemysłem i wojskiem oraz sformułowano wnioski końcowe.
The role of actively diffusing impurities
of sulfur and oxygen in ductility-dip
cracking susceptibility of Ni-Cr-Fe welds
Authors: Yushchenko K.A. , Zviagintseva A.V. , Kapitanchuk L.M. , Gakh I.S.
Published: October 2018

Purpose: To determine the temperature conditions of sulphur and phosphorus moving to
sample surface for alloys with different initial sulphur content.
Design/methodology/approach: Investigation of samples from In 690, Kh20N16AG6,
In52MSS alloys in Auger spectrometer JAMP-9500F for determination of the probability of
saturation of the free surface (as grain boundary model) with sulphur from the solid solution.
Results obtained without removing the samples from the chamber, stage-by-stage heating
up to 800°C with determination of element content every 100°C.
Findings: It is shown that sulphur has the tendency of diffusing to the interface from the
middle of the grain body and forming segregations in the form of a monolayer even at its
slight (0.00015 wt.%) content in the alloy.
Research limitations/implications: Presence of actively diffusing impurities (C, O, H,
S, P), dissolved in the metal, in the case of a gradient of temperatures and stresses, leads
to redistribution of these impurities between the solid solution and surface of the sample,
or solid solution and grain boundaries (interface). According to the obtained data, change
of elemental composition proceeds within 0.5-1 nm from the grain boundary or from the
sample surface and leads to formation of monolayers.
Practical implications: To prevent the formation of cracks it is necessary not only to
reduce the content of impurity elements in the alloy, but to prevent moving them to the
boundary of grains and creating mono layers.
Originality/value: For the selected alloys, the formation of monolayers is the most
intensive at temperatures of 700-800° that coincides with DTR in the temperature range of
0.6-0.8 Ts. Such monolayers can lead to ductility dip cracks formation.
The joint effect of vanadium and nitrogen
on the mechanical behavior of railroad
wheels steel
Authors: Kulyk V.V. , Shipitsyn S.Ya. , Ostash O.P. , Duriagina Z.A. , Vira V.V.
Published: October 2018

Purpose: The aim of the proposed research is to investigate the regularities of the microstructure
change, fracture micromechanism and mechanical service characteristics of the
high-strength wheel steel with a lowered carbon content under static, impact and cyclic
loading depending on the total content of vanadium and nitrogen and also the steel heat
treatment modes.
Design/methodology/approach: Alloying with vanadium was carried out in the range
of 0.09-0.23% and nitrogen in the range of 0.006-0.018%. All steels were heat treated by
normalizing and subsequent tempering at different temperatures in the range of 450-650°C.
Steels microstructure was investigated by the optical metallography methods on the microscope
EPITIP-2 (Carl Zeiss Jena). Scanning electron microscope Zeiss-EVO40XVP was also used for
microstructural and microfractography investigations. Static strength (UTS), relative elongation
(TEL), impact toughness tests (KCV) and fatigue crack growth resistance characteristics
(fatigue threshold ΔKth, cyclic fatigue fracture toughness ΔKfc) were determined on standard
specimens. Rolling contact fatigue testing was carried out on the model specimens.
Findings: The regularities of the change of microstructure, fracture micromechanism and
mechanical characteristics of the high-strength wheel steel with a lowered carbon content
under static, impact and cyclic loading depending on the total content of vanadium and
nitrogen and also the steel heat treatment modes are studied.
Research limitations/implications: The results obtained on laboratory samples should
be tested during a real railway wheels investigation.
Practical implications: The steel with the optimal parameter [V∙N]∙104 = 22.1% provides
high tread surface damaging resistance established on the model wheels.
Originality/value: It was established that after normalization at 950°C and tempering at
550°C the increase of ultimate strength UTS and cyclic fracture toughness ΔKfc by 4% and
19%, respectively; impact toughness at room (KCV+20) and low temperature (KCV-40) in
1.5 and 3.3 times, respectively, when parameter [V∙N]∙104 changes from 7.8 to 22.1% and
carbon content from 0.63 to 0.57%.
Theoretical study of food contamination
mechanisms by melamine and hazard
of melamine for health
Authors: Ziarati P. , Tamaskoni-Zahedi M. , Mostafidi M. , Shirkhan F. , Vambol S. , Vambol V.
Published: October 2018

Purpose: The purpose of this investigation is to theoretical study of food contamination
mechanisms by melamine and hazard of melamine for health. This purpose is justified
as follows. A high percentage of nitrogen has caused the abuse of this chemical, because
this amount of nitrogen brings about the properties of decomposition of protein molecules
into this material, as a result of the increase in melamine in foods. The primary issues
discussed are related to o introduce melamine and its sources to the potential of exposure
to melamine and to address the risks of this hazardous material and enhance the safety
of food products.
Design/methodology/approach: The investigation was carried out using analytical
analysis. Melamine accumulates in the body of humans and has different effects. The
presence of melamine at a very low level is also dangerous for children, and the food safety
incidents that occurred in 2008 were due to the presence of melamine in children's infant
formula in China, has raised concerns about food security around the world.
Findings: As a result analytical research we have this conclusion. Melamine is a chemical
compound that is widely used in industry and especially in the production of packaging
materials. Reducing the risk to human health can be achieved through the combined use
of three factors: using proper control programs to prevent melamine from getting into food,
preventing the migration of melamine in food and using no melamine detergents.
Research limitations/implications: The investigation was carried out on the basis
of open sources of information on the chemical properties of melamine, its presence in
household and other materials and its ability to interact with organic media.
Practical implications: The results of this study can be recommended to the Ministry
of Health and the Ministry of Industry for the development of control programs to prevent
melamine from getting into food.
Originality/value: The main problem of food pollution by melamine is that this substance
is contained in most packaging materials. And a study of the mechanisms the migration
of melamine in food and a generalization of the results on the methods for determining
melamine in food will help solve the problem of unhealthy food.
Mill Scales Blended Polymer Composites For Electrical Insulation Application
Authors: Beura Jayasmita , Biswal Susanta Kumar , Kundu Saurabh , Rout Tapan Kumar
Published: October 2018

Standalone composite films were prepared using modified polyester as a binder and waste iron oxides (mill scales) collected from a steel plant as inorganic filler. The morphology, structure, composition, strength and electrical insulation properties of polymer-iron composites were studied using various analytical techniques such as X-ray diffraction (XRD), Scanning electron microscope (SEM), Atomic force microscopy (AFM), optical microscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray fluorescence (XRF), Brunauer–Emmett–Teller (BET) test, particle size analysis and electrical insulation test. The mill scales collected from the hot strip rolling mill (HSM) have found to comprise three different phases such as wustite, magnetite and hematite. Composites prepared using mill scales were showing three times higher strength compared to the mother polymer film. Electrical insulation of these composites were found to increase in the range of 55-230 MV/mm with increasing iron oxide content from 0.0125 g to 0.25 g in 2.5 g polymer. These results show a potential research field on the mill scales based composites for various advanced applications in improving insulation behaviour of materials which can withstand at higher temperatures and electrical stresses.
VISUALISATION OF THE DIGITAL TRANSFORMATION OF THE MACHINE TOOL SECTOR. TOWARDS INDUSTRY 4.0
Authors: GAVILANES TRAPOTE JAVIER , RIO  BELVER ROSA MARIA , CILLERUELO CARRASCO ERNESTO , RODRÍGUEZ ANDARA ALEJANDRO
Published: October 2018

The digital interconnection of the machines through the Internet is generating the Fourth Industrial Revolution (4IR). These "smart machines" are already transforming a wide variety of sectors, from manufacturing and agriculture to health and transport. This study aims to visualize and analyze the flows of technological knowledge leading to inventions that lead to industrial digitization with great impact on the value chain. Through the study of patents, we can observe how the technological advances characteristic of Industry 4.0 are contributing to generate new inventions in the Machine Tool sector. The sample, extracted from the European Patent Office's (EPO) global patent database, is comprised of all patent applications related to the 4IR and Machine Tool in the period 1990-2016. The study shows how in recent years the influence of 4IR on Machine Tools has grown exponentially, with industry 4.0 technologies related to hardware and data analysis and interpretation being the most cited in Machine Tool patents. American companies are the main contributors to the digitalization of the sector, followed closely by European companies, mainly German, and in the case of Chinese companies, the data indicate that their presence will increase considerably in the coming years.

Keywords: Machine tool; Fourth Industrial Revolution; Industry 4.0; Patents; Technological knowledge flows
ADDITIVE MANUFACTURING OF METAL COMPONENTS USING CONCENTRIC-WIRE LASER METAL DEPOSITION
Authors: PUJANA ASTARLOA JOSEBA , MADARIETA CHURRUCA MIKEL , GARMENDIA SAEZ IKER , LEUNDA ARRIZABALAGA JOSE
Published: October 2018

This work presents the development of the additive manufacturing process of large metal components based on concentric wire laser deposition technology. This technology is recognized as of great interest by the aeronautical sector as it would allow to reduce the cost of titanium components that currently require very expensive forging and machining operations.
Experimentally, the different types of failure of the deposition process are shown, as well as the different stages of the process, starting with single-weld deposition and ending with the construction of regular solid geometries. A priori, wire deposition has structural advantages compared to metal powder deposition. This work focuses on the adjustment of the process from a macroscopic and merely geometric point of view prior to the microstructural and properties analysis foreseen in future works.

Keywords: Laser Metal Deposition, Wire, Concentric, Cladding, Additive manufacturing, 3D printing
TOWARDS A 5G COMPLIANT AND FLEXIBLE CONNECTED MANUFACTURING FACILITY
Authors: JACOB TAQUET EDUARDO , ASTORGA JASONE , UNCILLA GALAN JUAN JOSÉ , HUARTE MAIDER , GARCIA CONEJO DAVID , LOPEZ  DE LA CALLE MARCAIDE LUIS NORBERTO
Published: October 2018

The incoming smart Industry 4.0 envisions fully interconnected scenarios to boost the efficiency, quality and performance of industrial processes. In this context, communication technologies play a pivotal role as the key tool that enables the interconnection among a priori isolated business processes, making the most of them and resulting in more powerful business-level applications and decision-making. In this paper, we present the application of two cutting-edge telecommunication technologies, namely, network function virtualization (NFV) and software-defined networking (SDN), to the manufacturing industry, showing how these technologies can help improve manufacturing processes. We introduce the SN4I (Smart Networks for Industry) experimental facility, which is an NFV- and SDN-aware communication network that connects the University of the Basque Country with the Aeronautics Advanced Manufacturing Centre. In this regard, NFV provides a flexible way to deploy virtual services, while SDN allows the programming of network elements to interconnect these virtual services by means of virtual links or virtual networks. Both technologies guarantee full data and performance level isolation, ensuring that virtual services running over the same physical hardware or virtual links deployed over the same physical network will never interfere with one another. With the integration of NFV and SDN in manufacturing networks, the design, evaluation and deployment time of services that include computational, storage and networking resources is drastically decreased, facilitating innovation and optimizing network and hardware resource utilization.

Key Words: 5G, experimental facility, Industry 4.0, manufacturing network function virtualization (NFV), software-defined networking (SDN)
AN INTEGRATED PROCEDURE TO IMPROVE NUMERICALMODELS IN MACHINE-TOOLS
Authors: HERNANDEZ VAZQUEZ JESUS MARIA , GARITAONANDIA AREITIO IKER , FERNANDES MARIA HELENA , MUÑOA GOROSTIDI JOKIN
Published: October 2018

In this paper, a procedure to improve Finite Element (FE) models of machine-tools is introduced. This procedure is applied to a machining center in two geometric configurations, in order to analyze the evolution of its dynamic behavior and evaluate the change of critical parameters such as the stiffness of joints. First, Design of Experiments (DoE) techniques are applied to set initial values of the parameters describing the machine joints. Then, using a model updating iterative technique that includes natural frequencies and mode shapes in the objective function, design parameters are modified to obtain an optimized FE model. Results confirm that the integration of updating and DoE techniques leads to obtain improved FE models that show similar modal parameters to those of the machine-tool. These models will allow to make changes in the design of the machine that contribute to reduce chatter.
Keywords: connections, updating techniques, design of experiments, dynamic behavior, machine-tool.
IMPROVEMENT OF THE SURFACE QUALITY OF INCREMENTALLY FORMED PARTS BY MEANS OF HYDROSTATIC BALL BURNISHING
Authors: IRIONDO PLAZA EDURNE , LOPEZ  DE LA CALLE MARCAIDE LUIS NORBERTO , RODRIGUEZ EZQUERRO ADRIAN , PENALVA OSCOZ MARILUZ , GIL ARIADNA , ORTIZ EDESA MIKEL
Published: October 2018

The research work presented aims to validate the operation of the hydrostatic ball burnishing as a strategy to improve the surface quality of an aeronautical component of Inconel 718, previously shaped by Asymetric Incremetal Sheet Forming (AISF). The combination of both processes, burnishing on AISF, has a very high level of innovation and is a pioneer in its application on an industrial component made of this high performance nickel-chromium alloy. The surface quality of the incrementally shaped component has been studied to subsequently apply a burnishing by means of the hydrostatic ball. The results obtained confirm the feasibility of the proposed strategy, with a reduction in roughness up to 30%, depending on the area treated.

Keywords: Asymetric Incremental Sheet Forning (AISF), Hydrostatic Ball Burnishing, Inconel 718, Surface finishing and Roughness.
USE OF STATISTICAL CORRELATION FOR ENERGY MANAGEMENT IN OFFICE PREMISES ADOPTING TECHNIQUES OF THE INDUSTRY 4.0
Authors: HERNANDEZ  LUNA MONICA , ROBLEDO FAVA ROBERTO , FERNANDEZ DE CORDOBA CASTELLA PEDRO , PAREDES ANGEL , MICHINEL  ALVAREZ HUMBERTO , ZARAGOZA FERNANDEZ SONIA
Published: October 2018

We present a statistical analysis of correlations between carbon dioxide concentration and energy consumption in workplaces, with the goal of enabling its eventual programming in energy platforms In Cloud for improving management and enhancing automation and control in the service sector industry. A low-cost system is used to measure and transmit the data of buildings and the information can be analyzed by any remote device. The study includes data measured during one year in two offices located at Sada (A Coruña, Spain) and Clayton (Panama). We present linear and nonlinear regression curves, show that there are significant positive correlations and discuss seasonal and climate-related aspects. We argue that this kind of analysis can provide useful information for the design and operation in the service industry, through web-based energy platforms for control and automation.

Keywords: Industry 4.0, intelligent energy platforms, energy consumption, statistical analysis, automation of facilities, control of facilities.
SPANISH NAVY AND RELIABILITY CENTERED MAINTENANCE
Authors: SUÁREZ GARCÍA ANDRÉS , REY GUILLERMO , ARCE FARIÑA ELENA , ALVAREZ FEIJOO MIGUEL ANGEL
Published: October 2018

The Spanish Navy's maintenance strategy for systems, ships and platforms has focused on corrective maintenance and on following the manufacturer's recommendations. This way of understanding maintenance is not applicable to modern and complex systems, as it causes numerous and significant failures; this has led the Spanish Navy to reconsider the maintenance methodology used, which has led to the consideration of reliability-based maintenance (RCM) as a solution.