bluuebunny/crossref_metadata_2025 huggingface dataset:
Factores que limitan la adopción de pagos electrónicos por las micro y pequeñas empresas en Tumbes, Perú
Authors: Hernández Camacho Brayan Steven
Published: September 2023

El objetivo de esta investigación es determinar los factores que limitan significativamente la adopción de pagos electrónicos por las micro y pequeñas empresas del departamento de Tumbes, Perú. Como principales factores presentados en este estudio tenemos, la infraestructura tecnológica, la seguridad, la cultura de comercio electrónico, y las características de los dueños de los negocios, esta investigación describe los resultados encontrados a través de una encuesta dicotómica aplicada de forma presencial y virtual a cincuenta y un dueños de micros y pequeñas empresas de diferentes sectores comerciales, ubicadas en Tumbes. Los resultados de esta investigación afirman que, en el departamento de Tumbes existe un alto porcentaje de MYPES que no cuentan con las herramientas necesarias para aceptar pagos digitales, aunque existe intención en el uso, la preferencia por el dinero físico es mayor, este estudio también revela el desconocimiento sobre la importancia y los beneficios que puede tener el uso de pagos digitales. Los desafíos asociados con la implementación de pagos digitales incluyen las características cualitativas de los dueños y el escaso conocimiento y la falta de cultura digital para la implementación de nuevas herramientas tecnológicas.Palabras clave: Pagos electrónicos, cultura de comercio digital, seguridad, MYPES.
buques autónomos y la responsabilidad del porteador
Authors: Herrero Urtueta Eduardo
Published: September 2023

En la actualidad la tecnología avanza a pasos agigantados, de manera que las novedades que la ciencia trae pueden llegar a sacudir los cimientos del Derecho que estaban plenamente asentados. La irrupción de los buques autónomos en el tráfico marítimo es una realidad a corto plazo y es preciso analizar el encaje de este tipo de buques en la normativa internacional. Al fin y al cabo, la ausencia de tripulación y la excesiva dependencia de un sistema de IA puede alterar el régimen tradicional que los diferentes textos regulan respecto a la responsabilidad del porteador.
A case study of bowel prolapses after induced abortion
Authors: Agrawal Neha , Malik Neeru , Dabas Richa
Published: September 2023

Induced abortion, the intentional termination of pregnancy, is among the most common of gynaecological procedures. Depending on country-specific abortion laws, where abortion laws are highly restrictive, abortion is unsafe leading to maternal morbidity and mortality. This is a case study of unsafe abortion. In this case a 25-year-old G3P2L2 with previous 2 normal vaginal delivery had uterine perforation with bowel prolapse through the vagina following an dilatation and curettage of a missed abortion of 7 week and 6 days in a private hospital. Following the procedure patient had severe abdominal pain and bleeding from vagina, magnetic resonance imaging (MRI) was done. Patient came to our hospital with MRI. Patient was taken for exploratory laparotomy with uterine repair, bowel resection and anastomosis. Even though MTP Amendment act 2021 in India is liberal and government provides free contraception and abortion services by trained personnel, due to ignorance and misinformation, female often undergoes unsafe abortion. Unsafe abortion causes mild discomfort to grave injury like bowel prolapse leading to maternal death. Best preventive measure is awareness and easy accessibility.
Uncharted territory: endometeriosis explored in the left canal of Nuck
Authors: Gupta Rekha , Sachar Chandrika , Aggarwal Phiza
Published: September 2023

In this captivating exploration, we unravel a perplexing case of endometriosis taking root within the enigmatic left canal of Nuck. A 33-year-old woman with a tenacious groin mass, manifesting occasional discomfort during menstruation, led us down a diagnostic rabbit hole. Through ultrasound and MRI revelations, a mass emerged, stretching through the left inguinal canal into the pubic domain. The subsequent cytological analysis solidified the diagnosis. While endometriosis, characterized by extrinsic endometrial tissue, typically confines its grip to the pelvic arena, this singular case defies convention. The canal of Nuck, a developmental vestige, reveals itself as a potential portal for endometrial cells under enigmatic conditions. Amid diagnostic intricacies, ultrasound and MRI step forth as guiding imaging tools. In a medical landscape rife with the known, this expedition into the uncharted expands our understanding and beckons us to probe further into the remarkable intricacies of Nuck's canal endometriosis.
Successful four flap reconstruction for extensive crush injuries of bilateral lower limbs using local pedicled flaps in a 73-year-old patient: a rare case report
Authors: Bhat Tanveer A. , Alokaili Hisham , Moazin Othillah , Daker Fatima O. A. , Alkadi Danah , Altamimi Abdulla S. , Mirza Mohammed Y.
Published: September 2023

Extensive soft tissue defects with periosteal stripping over critical areas of tibia pose a tough challenge to the reconstructive plastic surgeon. Treatment of choice for these defects is free tissue transfer. Local pedicled fasciocutaneous or muscle flaps are used only when the free tissue transfer is not possible. The gastrocnemius and soleus flaps either used as a combined flap or as individual separate flaps can be an alternate reconstructive option for these defects in selected cases. Here we report a 73-year-old male patient a case of extensive crush injury involving both lower limbs following a motor vehicle accident (MVA) in whom we have successfully reconstructed the extensive soft tissue defects with exposed tibia with four local pedicled flaps. The purpose of writing this case report is that when free tissue transfer is not possible in such extensive crush injuries, a durable functionally and cosmetically acceptable reconstruction with pedicled hemi gastrocnemius and medial hemisoleus flaps can be done after a meticulous planning and flap design without any significant functional donor site morbidity.
A rare case report of multiple calculi in an adult female having cystic nephroma
Authors: Kumar Satish Chandra , Alam M. Afsar , . Vimalraju , Kumar Nilay , Kumar Akhilesh , Kumar Sandip
Published: September 2023

A benign multilocular cyst is a benign, nondysplastic, neoplastic lesion that occurs most commonly either before the age of 4 years in males or after the age of 30 years in females. The only way to determine the diagnosis of a multilocular cystic lesion is by surgical excision. We report a case of 50 years old female with chronic left flank pain. After imaging like Ultrasonography, Intravenous pyelography, patient underwent nephrolithotomy with deroofing of the cyst under the impression of multiple renal calculi within a renal cyst. Histopathological examination showed that it was a multilocular cystic nephroma, a rare benign neoplasm of the kidney. This case report discusses the epidemiology, clinical presentation, radiological features, differential diagnosis and histopathology of this neoplasm.
Mefenamic acid triggered autoimmune hemolytic anemia in a child: a rare case report
Authors: Kiran Kumar Reddy Y. Ravi , Kavthekar Saiprasad Onkareshwar , Venkata Susmitha Narahari , Patil Nivedita Balasaheb , Kamble Priti , Deepika Chilukuru J. Satyamani
Published: September 2023

Autoimmune hemolytic anemia (AIHA) is characterized by the abnormal production of antibodies that bind to antigens on the surface of red blood cells (RBC), resulting in RBC destruction. Here we describe a rare case of mefenamic acid-induced AIHA in a 3-year-old boy who developed acute hemolysis after ingestion of mefenamic acid for febrile illness. The aim is to draw the attention of pediatricians to one of the side effects of mefenamic acid, the drug which is very commonly used as an antipyretic.
Dental management of a 3-year-old uncooperative child under general anaesthesia: a case report
Authors: Joshi Ambika , Saxena Nivedita , Marwah Nikhil , Singh Vritika , Singh Mrityunjay
Published: September 2023

Dental care is medically necessary for the purpose of eliminating and preventing orofacial disease, infection and pain, restoring the form and function of the dentition, and correcting facial disfiguration or dysfunction – American Academy of Pediatric Dentistry (AAPD). Lack of cooperation in young paediatric patients can be a confounding factor for dental rehabilitation procedures and even examination or radiographs. To complete necessary dental radiographs and/or treatment in young, uncooperative children general anaesthesia or deep sedation is often required. This article presents the case of a 3-year-old girl child with a complaint of sharp shooting pain in upper and lower left back tooth region and was extremely uncooperative. She was diagnosed with early childhood caries; full mouth rehabilitation was done under general anaesthesia. Clinical examination, classification and treatment plan are discussed based on the review of current literature available.
A long-term follow-up of a case of Rogers syndrome, Thiamine responsive megaloblastic anemia
Authors: Chaware Shriya , Jahagirdar Rahul , Deshpande Ruma , Bafna Vibha
Published: September 2023

Thiamine-responsive megaloblastic anemia (TRMA) also known as Rogers syndrome is a rare autosomal recessive disorder characterized by megaloblastic anemia, diabetes mellitus, and progressive sensorineural deafness. The disease can be manifested anytime between infancy and adolescence, and all the cardinal findings may not be present at the time of the diagnosis. The main defect lies in the active thiamine uptake into cells which is disturbed. Not many cases have been reported about the long-term follow-up of children with this disorder and their associated complications. We hereby report a 14 years follow-up of a girl with Rogers syndrome diagnosed at toddler age with nonresponsive anemia and diabetes and further progressed to have sensorineural hearing loss. Her clinical exome study showed a mutation in the SLC19A2 gene. This experience illustrates the relevance of a detailed evaluation and regular follow-up to assess the progression of the syndrome till her pubertal age.
Lung abscess preceded by fever of unknown origin: a case report
Authors: Buntara Ivan , Hidayat Sari Purnama , Buulolo Christina Siuwandy , Hendsun
Published: September 2023

Lung abscess is a condition that characterized by formation of pus or tissue necrosis in lung parenchyma. The prevalence of lung abscess in Indonesia is still unknown, but the incidence seems to be decreased. Lung abscess could be categorized in many forms based on the duration, etiology and the way of spreading. Early sign and symptoms usually cannot be differentiated from pneumonia. Lung abscess also could be preceded by fever of unknown origin, so it could be challenging to diagnose. This case report presented a-57-years old man that preceded by fever of unknown origin. Chest X-ray show unspecified lung infiltrate, thus treated as a pneumonia. Further X-ray showed the clear image of cavities with abscess. Lung CT-scan was performed and bronchiectasis also lung abscess were found. Comprehensive history taking, physical examinations and diagnostic tests were done in this patient until the diagnosis is established.
Gestational diabetes screening and management: the issues of GDM risk factors and phone number documentations
Authors: Gbeinbo Fortunatus D. , Bwititi Phillip T. , Nwose Ezekiel U.
Published: September 2023

Background: Gestational diabetes mellitus (GDM) if unmanaged can complicate pregnancy outcomes. Selective screening of GDM is a common policy hence, the need for complete medical records of patients. The extent and pattern that documentation of patients’ records can impact GDM screening-by-telehealth requires elucidation. The aim was to describe the effectiveness of phone contacts on medical records and GDM risk factors among a hospital-based antenatal clinic setting
Methods: This was an observational study in which previously reported antenatal records of patients screened for GDM were reviewed for effectiveness of phone contacts to do telehealth, and this was with simultaneous GDM risk assessment. Data were analysed by descriptive frequency counting.
Results: On effectiveness of phone details on medical records, 41/98 cases were reached, of which 31.7% have three or more GDM risk factors to fulfil selection criteria for laboratory screening of GDM. Prevalence of risk factors in initial routine data collection (24.9%), previous history assessment (21.3%) and at antenatal monitoring phase (37.8%), Among the 57/98 phone contacts that were unreached, 59.6% are switched off.
Conclusions: The observations highlight the need of concerted focus on policy and education, for both staff and patients, to improve documentation of correct and valid telephone details in medical records.
Functional and anatomical outcomes following cartilage myringoplasty
Authors: Mohan Nidhi S. , Mushannanavar Annapurna S. , Gadag Raveendra P. , Dandinarasaia Manjunath
Published: September 2023

Background: Myringoplasty using cartilage graft is being popular in recent years because of its better graft uptake and optimal hearing outcome. Thickness plays an important role in achieving optimal hearing outcome and although studies have shown 0.5 mm thickness to give better hearing results, concrete studies are lacking.
Methods: A prospective study was conducted in the department of otorhinolaryngology at a tertiary-referral-hospital in North-Karnataka; India between January-December 2019, on 25 patients of chronic otitis media; mucosal inactive or quiescent with conductive hearing loss and intact ossicular chain who underwent cartilage myringoplasty using conchal cartilage of 0.5 mm thickness. Follow-up was done at 3, 4½ and 6 months postoperatively to assess graft uptake. Hearing assessment was performed at the end of 6 months postoperative period with pure-tone audiometry.
Results: The preoperative mean pure tone average was 33.64±9.42 dB which improved to 22.56±7.41 dB at 6 months. At 3 months and 4½ months, there were 21casess (84%) of complete graft uptake, 3 cases of partial graft uptake (12%) and one case of total graft rejection (4%). Whereas, at 6 months postoperative period complete graft uptake was seen in 22 cases (88%) with 1 case of total rejection (4%) and 2 cases of partial uptake (8%).
Conclusions: Cartilage myringoplasty using 0.5 mm thickness conchal cartilage offers good hearing outcome in addition to significant graft uptake. As the conchal cartilage can be easily harvested from the site of incision for the surgery it can be an important primary alternative to temporalis fascia.
Tonsillar Schwannoma: a rare case report
Authors: Shukla Stuti , Pathak Vivek K. , Sharma Himani , Arora Kanika , Rizvi Sama
Published: September 2023

A Schwannoma is a benign, locally aggressive tumor that occurs due to the proliferation of Schwann cells of the nerve sheath. These tumors may involve any cranial nerve and hence are routinely missed on diagnosis. We report a rare case of a young adult female with unilateral tonsillar fossa mass which was excised by transoral approach, and histopathology reported to be a tonsillar schwannoma. Hence, it is necessary to be aware of these rare benign tumors as they can mimic a tonsillar hypertrophy.
LivrOnça: um conceito de livro na América Indígena
Authors: Menezes Vinícios Souza de
Published: September 2023

O texto está disposto em quatro momentos dialógicos: i) uma (re)introdução de um devir-América bibliográfico e contracultural, obliterado nas rasuras das escrituras coloniais, ii) uma arqueologia do conceito de livro a partir do advento no mundo grego antigo do anthropos como um doador de forma anímico-corporal aos grafismos alfabéticos do Ocidente, iii) a exposição do LivrOnça como um livro possível de Abya Yala, presente nas semiofagias da diferOnça (différonce) das gramatologias da América, e, por fim, iv) o último instante textual aborda os encantamentos finiciais, um presente fim como cessação da condição absoluta, desencantada e acabada do livro ocidental que se encanta através do (re)início ancestral, do endeusamento das coisas e da fabricação da vida pelas escrituras ameríndias dos povos da Terra Viva, também conhecida como Amoxtlapan, terra dos livros vivos. Diante de uma perspectiva teórica de argumentação, o texto caminha por meio dos agenciamentos terranos da geofilosofia proposta por Deleuze e Guattari e do diferimento espaço-temporal desconstrutivo do livro proposto por Derrida, entretanto, com uma diferença, ambos os métodos são devorados pelas perspectivas multinaturais dos povos ameríndios. Jaguarear o livro, este é o objetivo onçológico do texto.
What is a skrepny (staple`s) analysis – on the example of the story "Netochka Nezvanova" as an unbalanced text in Dostoevsky's idiostyle (as well as "Poor people" and "White nights" as texts with insufficiently expressed authorhip)
Authors: Mikheev Mihail
Published: September 2023

The article contains such well-known facts that Dostoevsky's stories "Netochka Nezvanova", "Poor People" and "White Nights" are deviations from the author's style, confirmed by statistical indicators of the use of small words in them, i.e. conjunctions, particles, discursive and introductory words, which are collectively referred to as staples. Because of this, the method we use can be called skrepny (staple’s) analysis. In total, there are 883 such units, according to the frequencies of which the authors differ, they are counted, on the one hand, in the analyzed text X, and on the other, in the corpus of all other texts, both the title text and any authors available in our database: now there are about 70 different authors in total XIX-XX centuries (or 77 different idiosyncrasies), and - 917 of their texts.
The main indicator is the total deviations: the sum of the absolute values of the differences between the frequencies of the use of staples in the analyzed text and – the average values of their frequencies in other texts of the same or some other author. At the same time, we record the following two phases of the "loss" of authorship:
at the 1st phase, text X loses a sufficient gap in the indicators of the total frequency deviations of all staples in the text of the titular author – a gap with the first or closest of all competitors-applicants for authorship – when such a gap is leveled and becomes approximately equal to the gaps (differences in deviations from the idiostyle of the analyzed text) between all other author's idiostyles, becoming almost indistinguishable from them: it is with such texts that the stories "Poor People", "White Nights", "Crocodile" and "Mr. Prokharchin" by Dostoevsky show themselves,
and at the 2nd phase, deviations from the idiosyncrasy of the analyzed text of someone (or several of the competitors at once) become even smaller than the deviations of the titular author himself, i.e. the gap becomes negative: thus, the chances of "authorship" no longer appear in the real author, but in someone else or immediately several of these competing authors - as in the case of the leading titular author of "Netochka Nezvanova" (in terms of the total frequency deviations in all staples) at once have 6 idiostyles – prose A.Panaeva, N.Pomyalovsky, Turgenev, Gogol, L.Tolstoy and V.Garshin.
Uso de substâncias psicoativas entre adolescentes escolares de Distritos Municipais
Authors: Dantas de Sousa Larissa Maria , Aragão Joyce Mazza Nunes , Azevedo de Sousa Francisco Matheus , Nazaré Oliveira Eliany , De Almeida Paulo César , Mazza Nunes Bezerra Soleane
Published: September 2023

Objetivo: analisar o uso de substâncias psicoativas entre adolescentes escolares. Método: estudo transversal, de abordagem quantitativa, realizado em 2021, com 199 alunos de quatro escolas estaduais de Ensino Médio localizadas nos Distritos de um Município do interior do Ceará. Utilizou-se um questionário autoaplicável, DUSI (Drug Use Screening Inventory). Resultados: 92 (46,2%) alunos cursavam o 1° ano do ensino médio, eram do sexo feminino 114 (57,3%), com idade predominante de 15 a 16 anos (N 31 65,9%). Os adolescentes relataram o uso de todas substancias pesquisadas, mesmo que fosse somente de uma a duas vezes no último mês. Foram prevalentes:  analgésicos (15,6%), álcool (14,5%), tranquilizantes (4,5%) e maconha (2,5%). Quase totalidade dos participantes negou o uso de tabaco nos últimos 30 dias. A maioria dos participantes negou ter problemas associados ao uso dessas substâncias psicoativas Conclusão: o estudo auxiliou na compreensão das substâncias psicoativas mais consumidas entre os alunos do Ensino Médio de Distritos Municipais, permitindo ampliar os conhecimentos sobre o uso de drogas no ambiente escolar. Esse achado demonstra a presença dessas substâncias e o uso entre os adolescentes mesmos nos locais mais distantes dos grandes centros urbanos.
POESIA E PROGRAMAÇÃO: O MULTIFACETADO USO DO CONCEITO DE “LINGUAGENS” NA ARTE POR MEIO DO PROJETO LABORATÓRIO DE LINGUAGENS DO PANTANAL
Authors: Bittar Domingues Gabriel , Sá de Assunção Lucas , Henrique de Oliveira Lopes Lucas
Published: September 2023

O propósito do artigo que segue é apresentar resultados oriundos de projeto de iniciação científica intitulado “Laboratório de Linguagens do Pantanal”, desenvolvido com o apoio da Fundect/MS. O projeto teve como objetivos: i) investigar temáticas relacionadas à poética de Manoel de Barros; ii) estudar linguagens de programação e ferramentas de desenvolvimento web; iii) criar um website em que se pudesse divulgar o conhecimento acadêmico e científico obtido por meio do projeto ao público amplo, de maneira a combinar tais conhecimentos com uma estética que fizesse referência à obra de Manoel. Os artigos, que são frutos do projeto, foram então condensados e inseridos neste artigo único. O primeiro tem por intuito a discussão de temáticas de base filosófica para a leitura da poesia de Manoel de Barros, identificando uma poesia que quebra paradigmas sociais e subverte normas gramaticais, colocando a linguagem em evidência. Já o segundo tema abordado vai no sentido do questionamento sobre a maneira com que Manoel de Barros com o tempo se intitulou vagabundo profissional, e sobre a sua maneira de ver arte em coisas que não tinham significado para um padrão artístico, criticando de maneira sutil a formalidade e a razão que os críticos tendem a usar em relação a arte, deixando de lado muitas das vezes o modo simples das pessoas se expressarem e mostrarem seus sentimentos através de diversas formas de expressão artística. Este artigo segue a metodologia de revisão bibliográfica em artigos e livros e outros materiais referentes às temáticas abordadas. Os resultados foram organizados e publicados no website www.conhecendomanoel.com, aberto ao amplo acesso público.
CRIATIVIDADE E GESTÃO NA INDÚSTRIA CALÇADISTA
Authors: Rambo Roberta Werner , Pinheiro Cristiano Max Pereira , Barth Mauricio , Machado Raquel Engelman
Published: September 2023

O setor calçadista mostra-se relevante e tradicional na economia brasileira. Por ser vinculado a moda, é fácil a vinculação da criatividade ao design e desenvolvimento do produto – o calçado. Todavia, a criatividade não está ligada apenas ao processo criativo de produtos, podendo ser encontrada em qualquer ideia nova e adequada à situação. Este estudo busca, portanto, verificar a relação entre a criatividade e a gestão de indústrias calçadistas. Para tanto, realizou-se uma revisão sistemática de literatura com seleção de artigos no Portal de Periódicos Capes. A busca, dadas as limitações e critérios de seleção, resultou em quatro títulos que foram analisados pelos autores. Os resultados indicam que a criatividade está relacionada à gestão de empresas calçadistas, principalmente no que tange ao desenvolvimento de novos produtos, o conhecimento da organização e o marketing. Pode-se identificar, ainda, forte relação da criatividade com a inovação nas empresas, sendo a criatividade, normalmente, antecessora da inovação.
Clinical Significance of Blood Transfusions in Animals: A Review
Authors: . Ramakant , Sarkar T.K. , Verma Amit Kumar , Thakur Vipul , Maurya Pankaj Kumar , Gautam Sachin , Varun V.K. , Deepak Desh
Published: September 2023

Blood transfusion is a simple form of transplantation. Blood transfusion therapy is carryout since long back to improve the oxygen carrying capacity and treat the clinical sign of anaemia. The clinical use of blood transfusion in veterinary practice has recently increased as an emergency life-saving modality because of easy access to blood products along the blood donors or stored blood substitutes. Animal should be screened properly for blood typing and cross matching before the blood transfusion. The quantity of blood has to be transfused based on the clinical status of the recipient animals. Administration of blood products carries an inherent risk of transmission of disease carried by the donor. A transfusion can be rejected and cause profound, potentially life- threatening complications in the recipient. The developments in the techniques for separating different components of the blood have made considerable advancements in demand based treatment in veterinary medicine.
Planta de segregación de residuos sólidos y Centro de interpretación ambiental en el Parque Zonal Sinchi Roca
Authors:   , Franco Leon Claudia Beatriz
Published: September 2023

La investigación para una Planta de segregación de residuos sólidos y Centro de interpretación ambiental parte del interés de aportar, en algún nivel, en la regeneración del medioambiente y la mejora de la calidad ambiental tras identificar a la gestión de los residuos sólidos en la ciudad de Lima como uno de los principales factores de la contaminación ambiental asociado a repercusiones negativas en la salud de la población. Para el proyecto se plantean dos tipologías bastante diferentes, una industrial y otra cultural, en respuesta a dos necesidades: una infraestructura que acondicione residuos sólidos inorgánicos (plástico, papel-cartón, vidrio y metal) para insertarlos en un mercado desabastecido de reciclaje y evitar que terminen en rellenos sanitarios, que están llegando a su límite de capacidad; y un equipamiento museístico que promueva la concientización y las buenas prácticas ambientales, ya que las acciones de ciudadanos desinformados son causa de problemas como la mala disposición de los residuos en vías públicas y zonas naturales. Se concluye que es pertinente abordar tanto un enfoque productivo como uno de difusión para lograr una solución complementaria e integral, en donde la Planta de segregación pueda servir como exposición para que los visitantes del Centro de interpretación vean el proceso de recuperación en vivo; y, a su vez, el Centro promueva la segregación de los residuos en la fuente para que llegue una mayor cantidad de desechos inorgánicos a la Planta de segregación para ser aprovechados.
Sistema de integración de herramientas para la implementación A/B Testing de una sociedad administradora de fondos inversión
Authors:   , Geldres Del Carpio Fabian Samir , Huamaní Sifuentes Carlos César
Published: September 2023

Este documento tiene como propósito la propuesta de una solución que mejore la trazabilidad de requerimientos relacionados al empleo de la técnica A/B testing durante la concepción de la idea hasta la implementación de la versión más relevante para el negocio dentro de un marco de trabajo ágil. El analista de marketing registra el experimento desde el portal propuesto y luego el product owner cuenta con la opción de observarlo o aprobarlo. Cuando el product owner apruebe el experimento, este automáticamente es registrado en el sistema “Jira Software” como una historia de usuario a desarrollar por el equipo de desarrollo. El experimento mantiene su estado actualizado según como se encuentre en el sistema “Jira Software”. Una vez que la historia de usuario pase a estado completado en el sistema “Jira Software”, el sistema propuesto cambia el estado del requerimiento de marketing al estado “en producción” y comienza el seguimiento de los datos provenientes del sistema “Amplitude”. El analista de marketing podrá seguir los resultados del experimento desde el sistema propuesto y cuando este crea conveniente puede dar por finalizado el experimento. Cuando esto suceda el analista de marketing debe indicar que versión será implementado de manera definitiva. Luego, se crea una historia de usuario en el sistema “Jira Software” adjuntando la versión del experimento a ser implementado. El analista de marketing será notificado por cada cambio de estado por el que pase el experimento durante todo su ciclo de vida.
A inter-relação entre os espaços livres e os recursos hídricos urbanos: uma revisão sistemática da literatura
Authors: Torres Thaís Ferreira , Oliveira Daniela Bogado Bastos , Oliveira Vicente Paulo Santos
Published: September 2023

With the rapid urban growth, the expansion of cities has significantly impacted the environmental dimension. Within cities, open spaces play an important multifunctional role, being areas not occupied by buildings and with social, political and cultural relevance. The Open Space System (OSS) involves elements and relationships that structure this set of open spaces, including its water network, and its understanding is essential for the development and quality of life in urban areas. This bibliographic research used the Systematic Literature Review to understand the state of the art of scientific productions that interrelate public open spaces with water resources. Articles, dissertations and theses were selected. Bibliometric analysis revealed that the topic is widely discussed in specialized journals and has been researched in several countries. This systematic review contributed to outline the relationship between open spaces and water resources, highlighting the importance of integrated urban planning that promotes the conservation of natural resources and the creation of a sustainable urban environment.
Next-generation sequencing-based newborn screening initiatives in Europe: an overview
Authors: Bros-Facer Virginie , Taylor Stacie , Patch Christine
Published: September 2023

Aim: This article describes results from a survey targeting healthcare professionals (HCPs) leading newborn screening (NBS) initiatives in Europe. The survey was developed within the framework of a dedicated working group set up by the International Rare Diseases Research Consortium (IRDiRC) to gather collective efforts relating to NBS. The objectives of the survey were to gain a better understanding of approaches being tested for the expansion of NBS and to raise awareness of the significant momentum across Europe to evaluate novel technologies for use in future NBS programs.

Methods: A web-based survey including 57 questions was developed to gather information about genomic newborn screening initiatives in Europe that are using next-generation sequencing (NGS) as a first-tier test. Responses were analyzed qualitatively, and aggregated results are presented herein. The identity of some initiatives is not presented to preserve confidentiality.

Results: The findings of the survey indicated that most initiatives are in the planning stage and have not yet started. Although all 14 studies are heterogeneous in design, there is broad consensus that NGS approaches to NBS will, in the short term, be implemented in parallel with current screening programs. The results of this survey can be used to inform the design of studies still in the early planning stages.

Conclusion: Here, we provide an overview of NGS-based initiatives in Europe. Importantly, the initiatives described herein will generate evidence to evaluate the utility and feasibility of NGS approaches to NBS, thereby shortening the pathway to responsible implementation of NGS in NBS and informing future research efforts.
Short-Term Power Demand Forecasting Using Blockchain-Based Neural Networks Models
Authors: Wang Ruohan , Chen Yunlong , Li Entang , Xing Hongwei , Zhang Jianhui , Li Jing
Published: September 2023

With the rapid development of blockchain technology, blockchain-based neural network short-term power demand forecasting has become a research hot spot in the power industry. This paper aims to combine neural network algorithms with blockchain technology to establish a trustworthy and efficient short-term demand forecasting model. By leveraging the distributed ledger and immutability features of blockchain, we ensure the security and reliability of power demand data. Meanwhile, short-term power demand forecasting research using neural networks has the potential to increase the stability of the power system and offer opportunities for improved operations. In this paper, the root mean-square-error model evaluation indicator was used to compare the back propagation (BP) neural network algorithm and the traditional forecasting algorithm. The evaluation was performed on the randomly selected five household power datasets. The results show that, by comparing the long short-term memory network (LSTM) model with the BP neural network model, it was determined that the average prediction impact increases by about 25.7% under stable power demand. The short-term power prediction model of the BP neural network has the average error values more than two times lower than the traditional prediction model. It was shown that the use of the BP neural network algorithm and blockchain could increase the accuracy of short-term power demand forecasting, allowing the neural network-based algorithm to be implemented and taken into account in the research on short-term power demand forecasting.
Cartographier les pressions sur la biodiversité : pourquoi et comment ?
Authors: ROUVEYROL Paul , PRIMA Marie-Caroline , CHERRIER Olivia , SUAREZ Léa
Published: September 2023

Cartographier le niveau d’intensité des pressions sur la biodiversité est un outil précieux pour le pilotage des politiques de conservation. Nous présentons ici le premier catalogue de cartes de ce type en France, développé dans le cadre de la stratégie nationale pour les aires protégées. Il repose sur l’identification des pressions dont l’impact est le plus significatif sur le territoire puis sur la recherche de données appropriées. Sur 41 pressions identifiées, 27 ont pu être cartographiées en métropole et des cartes ont également été produites en Outre-mer. Elles s’appuient sur des données de source et nature très variées. Des cartes de synthèse cumulant le niveau de différentes pressions générées par un même secteur d’activité sont également proposées. Ce travail a vocation à être croisé avec des cartographies d’espèces et habitats patrimoniaux pour prioriser la création d’aires protégées, mais peut aussi être mis à profit par d’autres acteurs de la conservation
Emerging Technologies Transforming Therapy
Authors: Weaver Edward , Lamprou Dimitrios
Published: September 2023

The advancement of healthcare therapies is under constant development due to changing demographics and evolving disease-states. To ensure continuous furtherance of the healthcare system capacity to treat such ailments, emerging technologies (ETs) are coming to the forefront of medicine. It’s the hope that ETs are capable of covering a broad scope of therapeutic treatment areas, enabling novel pharmaceutical pathways to be established. Highlighted in this mini review are examples of focus ET areas, including additive manufacturing (AM), microfluidics (MFs), microelectromechanical systems (MEMS) and machine learning (ML), that have shown promising qualities and should be targeted further to improve patient outcomes.
Policy Proposal for Elderly Government Officials Employment in Public Sector Organizations
Authors: Chatthong Nisachon , Amornsiriphong Somsak , Sirisunhirun Somboon , Rugchatjaroen Krish , Torut Buraskorn
Published: September 2023

A promoting work for the elderly is an important way of empowering the participation of the elderly in society for economic development, which will lead to the well-being of the elderly. This is presented the policy proposal for elderly government officials employment in public sector organizations landscape study by policy research on EDFR which combines MACR, especially, elderly civil servants in public sector organizations of 56 - 60 years, and aged of 60 years to over, include the experts into the data. Comparing the employment forms elderly civil servants in public sector organizations of flexible employment and new employment models to differences at statistical significance level of 0.01, 0.05, respectively. Significance the policy proposal for elderly government officials employment at “Key” factors of the strategies, goals, measures, and operational guidelines to effectiveness.
Optimal Laboratory Cultivation Conditions of Limnospira maxima for Large-Scale Production
Authors: Pineda-Rodriguez Yirlis Yadeth , Herazo-Cardenas Diana Sofia , Vallejo-Isaza Adriana , Pompelli Marcelo F. , Jarma-Orozco Alfredo , Jaraba-Navas Juán de Dios , Cordero-Ocampo Jhony David , Gonzalez-Berrio Marianella , Arrieta Daniela Vegliante , Pico-Gonzalez Ana , Ariza-González Anthony Ricardo , Aviña-Padilla Katia , Rodriguez-Paez Luis Alfonso
Published: September 2023

Limnospira maxima is widely cultivated due to its abundance of proteins, carbohydrates, vitamins, minerals, essential fatty acids, and phycobiliproteins. However, limited information, high production costs, and nitrogen source limitations have hindered the optimal utilization of this cyanobacteria. The main goal of this study was to address these limitations by identifying ideal cultivation parameters to maximize yields, reduce costs, and contribute to global food security. It was demonstrated that the white and yellow light spectra are the most suitable for cultivating L. maxima, and the use of KNO3 as a nitrogen source proved to be the most cost-effective on a large scale. Nitrogen deficiency stimulates the production of dry biomass but also affects the concentration of key pigments such as chlorophyll and phycocyanin. A notable characteristic of L. maxima is its adaptability and survival capability in various environmental conditions, including nitrogen-deficient environments. This resilience is achieved through the degradation of phycobilisomes and the storage of glycogen. By identifying the optimal growth conditions and understanding the physiological responses of L. maxima, cultivation practices can be improved to be more efficient and sustainable.
Community Exercise Program Participation and Mental Well-Being in the U.S. Texas-Mexico Border Region
Authors: Reininger Belinda M , Ochoa Del-Toro Alma G. , Mitchell-Bennett Lisa A , Machiorlatti Michael , Robledo Candace A , Davé Amanda C , Lozoya Rebecca N
Published: September 2023

Hispanics are disproportionately affected by low rates of physical activity and high rates of chronic diseases. Hispanics generally and Mexican Americans specifically are underrepresented in research on physical activity and its impact on mental well-being. Some community-based interventions have been effective in increasing physical activity among Hispanics. This study examined data from a sample of low-income Hispanic participants in free community exercise classes to characterize the association between self-reported frequency of exercise class attendance, intensity of physical activity, and participant well-being. As part of two cross-sectional samples recruited from a stratified random sample of community exercise classes, 302 participants completed a questionnaire consisting of a modified version of the Godin-Shephard Leisure-Time Exercise Questionnaire (LTEQ) and the Mental Health Continuum Short Form (MHC-SF). Adjusted binary logistic regression analyses indicated that those who achieve moderate and strenuous self-reported physical activity have 130% higher odds (p = 0.0422) of positive mental well-being after adjustment for age, attendance, and self-reported health. This study provides evidence that physical activity intensity and time are associated with flourishing mental health among Hispanics. The study provides insight into the planning and development of community-based physical activity programming tailored to low-income populations.
Strengthening Primary Healthcare in Jordan for Achieving Universal Health Coverage: A Need for Family Health Team Approach
Authors: Khader Yousef , Al Nsour Mohannad , Abu Khudair Sara , Saad Randa , Tarawneh Mohammad Rassoul , Lami Faris
Published: September 2023

Achieving Universal Health Coverage (UHC) is a strategic objective of the Jordanian Government and has been prioritized in its strategies and plans. However, there are several challenges affecting primary health care in Jordan and the health system in general that prevent Jordan from achieving UHC. This paper highlights the importance of team-based care in the form of Family Health Teams (FHTs) to realize Jordan’s goal of achieving UHC. FHTs are a team-based approach that brings together diverse professionals to provide a comprehensive, efficient, patient-centered primary care system that meets the changing needs of Jordan's population and refugees. However, the implementation of FHT may encounter obstacles, including individual, organizational and institutional, and external barriers. To overcome such obstacles, several actions and processes need to be taken, including political commitment and leadership, implementing good governance and policy frameworks, allocating resources and funding, multisectoral collaboration, and engagement of communities and stakeholders. The successful implementation of FHTs requires participation from government officials, parliamentarians, civil society, and influential community, religious, and business leaders. A strategic policy framework, effective oversight, coalition building, regulation, attention to system design, and accountability are also essential. In conclusion, adopting the FHT approach in Jordan's Primary Health Care system offers a promising path towards achieving UHC, improving healthcare access, quality, and efficiency while addressing the unique challenges faced by the country's healthcare system.
Dynamics of the Capillary Lactate Levels in Patients with Out-of-Hospital Cardiac Arrest
Authors: Vujanović Vitka , Borovnik Lesjak Vesna , Mekiš Dušan , Strnad Matej
Published: September 2023

Background and Objectives: Effective strategy to cardiopulmonary resuscitation should be based on tissue perfusion. Our primary aim was to determine the association between capillary lactate values and initial rhythm as well as probability of return of spontaneous circulation in out-of-hospital cardiac arrest patients. Materials and Methods: This prospective observational cohort study included all patients with non-traumatic out-of-hospital cardiac arrest, older than 18 years, resuscitated by a prehospital emergency medical team between April 2020 and June 2021. Capillary lactate samples were collected at the time of arrival and every 10 minutes after first measurement until the time of return of spontaneous circulation (ROSC) or if ROSC was not achieved at time of declaring death on scene. Results: 83 patients were enrolled in the study. ROSC was achieved in 28 patients (33,7%), 21 were admitted to the hospital (26,3%) and 6 (7,23%) of them were discharged from the hospital. At discharge all patients had Cerebral Performance Category Scale 1 or 2. Initial capillary lactate values were significantly higher in patients with non-shockable rhythm compared to the group with shockable rhythm (9,19 +/- 4,6 versus 6,43 +/- 3,81; p = 0.037). A significant difference persisted also in a second value taken 10 minutes after in-itial value (10,03 +/- 5,19 versus 5,18 +/- 3,47; p = 0.019). Capillary lactate values were higher in the ROSC group and non-ROSC group at the time of restored circulation (11,10 +/- 6,59 and 6,77 +/- 4,23, respectively; p = 0,047). Conclusions: Capillary lactate values are significantly lower in patients with a shockable first rhythm in OHCA. There is also a significant connection between a rise in capillary lactate level and ROSC.
Deep Learning Theories and Methods for Breast Cancer Classification
Authors: Wang Mengke
Published: September 2023

Breast cancer is a common malignant tumour and studies have shown that early and accurate detection is crucial for patients. With the maturity of medical imaging and deep learning development, significant progress has been made in breast cancer classification, which greatly improves the accuracy and efficiency of classification. This review focuses on deep learning, migration learning, GAN, and lifelong learning to elaborate and summarise the important roles arising from breast cancer detection. This review also examines the dataset and labeling issues required for breast cancer classification. In conclusion, at the end of the article, we look at future directions for breast cancer classification research, including cross-migration learning, multimodal data fusion, model interpretability, and lifelong learning, and also explore how to provide personalized treatment plans for patients.
Are We Ready to Recommend Capsaicin for Disorders Other than Neuropathic Pain?
Authors: Silva Janayne Luihan , Santos Elandia A , Alvarez-Leite Jacqueline I
Published: September 2023

Capsaicin, a lipophilic, volatile compound, is responsible for the pungent properties of chili peppers. In recent years, a significant increase in investigations into its properties has allowed the production of new formulations and the development of tools with biotechnological, diagnostic, and potential therapeutic applications. In this way, the possible clinical application of such compound is expanding every year. This opinion article aims to provide a synthesis of recent findings regarding the mechanisms by which capsaicin participates in the control of non-communicable diseases such as obesity, diabetes, and dyslipidemia. This opinion review also discusses the recent findings and clinical studies of the use of capsaicin in body weight control.
Assessing Cumulative Nitrous Oxide Emissions during both Rice Cultivation and Fallow Phases: A Three-Year Case Study in South Korea
Authors: Ju Okjung , Kang Namgoo , Soh Hoseup , Park Jung-Soo , Choi Eun-Jung , Jeong Hyeon-Cheol
Published: September 2023

Rice cultivation serves as a significant anthropogenic source of methane (CH4), a primary greenhouse gas, and nitrous oxide (N2O), a secondary greenhouse gas. Although N2O emissions remain relatively small compared to CH4 emissions, they are remarkably affected by nitrogen-fertilized soil conditions during rice cultivation. To date, investigations are very limited concerning N2O emissions from rice cultivation in relation to environmental factors such as temperature, rainfall, and soil properties. In this case study, we investigated the characteristics of N2O emissions in the central region of South Korea, where a single rice cropping cycle occurs annually over a span of three years, from May 2020 to May 2023. We investigated the impact of variations in temperature and soil moisture on N2O emissions during rice cultivation. In this context, we attempted to discover the complex dynamics of N2O emissions by comparing longer fallow periods with the rice cultivation periods and extended non-dry periods with irrigated periods. We observed that extremely high N₂O flux events encountered during the fallow period appeared to have a substantial impact on the yearly cumulative N₂O emissions, surpassing the impact of cumulative N₂O emissions during the rice cultivation period. We found that high N₂O flux events arose not only from artificial nitrogen inputs but also due to temperature and soil moisture variations influenced by weather conditions. We concluded that assessing N₂O emissions solely based on the rice cultivation period would underestimate annual emissions. To prevent underestimation of N₂O emissions, continual gas collection throughout a year covering both rice cultivation and fallow phases is required in align with monitoring of varying temperature and soil moisture conditions. Based on our findings, we recommend that at least a three whole year evaluation period is needed to ensure estimation accuracy of N₂O emissions under varying nitrogen fertilization rates. Also, the findings from this study would help prepare a further revision or refinement of N2O emission factor from rice cultivation in the national greenhouse gas inventories defined by the inter-governmental panel on climate change (IPCC).