bluuebunny/crossref_metadata_2025 huggingface dataset:
Serious Games for Public Safety: How Gamified Education Can Teach Ontarians Emergency Preparedness
Authors: Le Annie N.
Published: November 2022

According to the Canadian Emergencies act, a national emergency is an urgent, critical situation that threatens the health and safety of Canadians (Department of Justice of Canada, 2022). Emergencies can also take on many forms: pandemics, natural disasters, civil unrest, or armed conflict. Currently, the Provincial Emergency Response Plan implemented by the Chief of Emergency Management Ontario is the framework that keeps Ontarians safe, allowing for organizations and municipalities to organize disaster relief, send out emergency alerts, and educate Ontario residents on emergency preparedness (PERP, 2019). This paper explores how serious games can prepare the public for emergencies based on response frameworks currently in use in metropolitan Ontario, Canada (cities such as Toronto, Ottawa, and Hamilton). This example was selected because it represents modern urban settings that require response plans and provides a framework that can be used to elaborate on. This paper will present the positive features of serious game applications concerning public safety and emergency management education. Case studies of serious game applications currently used for public health and safety purposes will be examined. Serious games may be a useful instrument for public safety education to enhance existing emergency preparedness and public safety education frameworks.
Research on Ideological and Political Path Innovation and Application Practice of English Major Courses in Chinese Universities
Authors: Feng Yang , Wang Xiya
Published: November 2022

In view of the current situation that the ideological and political effects of Chinese college courses are not very satisfactory and the anti-China waves in the West are constantly trying to provoke the color revolution, this study carried out an education experiment on the achievements of China’s reform and opening up for one semester among 232 college students of ZW University in China. The experiment found that nearly 90% of the 117 students in the experimental group who participated in the activity of “picture/video translation comparison+C2C international communication” accepted and affirmed the education model, and have significantly improved their patriotic consciousness, life belief, career ideal, plans for the postgraduate entrance examination, and enthusiasm for learning, and has greatly improved their English application ability, spread Chinese stories, and made friends with foreign netizens. However, 115 students in the control group who did not participate in the activity to maintain their original learning and living conditions had no significant changes in the above test indicators. At the same time, the final exam scores of the three English major courses in the experimental group were 16.69% higher than those in the control group.
Real-world weight changes in people with HIV-1 at risk of weight gain (female, Black or Hispanic) switching from integrase strand transfer inhibitors
Authors: Donga Prina , Emond Bruno , Shah Aditi , Bookhart Brahim K , Anderson David , Vermette-Laforme Maude , Rossi Carmine , Lafeuille Marie-Hélène
Published: November 2022

Aim:Compare weight changes between people living with HIV-1 (PLWH) at high risk of weight gain (females, Blacks or Hispanics) switching from an integrase strand transfer inhibitor (INSTI) to a protease inhibitor (PI) or another INSTI.Materials & methods:Mean weight changes from pre-switch to up-to-12 months post-switch were retrospectively compared between PLWH switching to a PI or INSTI.Results:356 PLWH were eligible. At 9- and 12-month post-switch, weight increases were observed for INSTI (weight: +1.55 kg and +1.59 kg), while decreases were observed for PI (-0.23 kg and -1.59 kg); differences between cohorts widened over time.Conclusion:These data suggest that switching off an INSTI may be a management tool to mitigate or reverse weight gain.
Flora del Valle de Tehuacán - Cuicatlán. FABACEAE Subfamilia CERCIDOIDEAE
Authors: Torres Colín Rafael
Published: November 2022

La publicación documenta la diversidad de plantas vasculares que existen en la región semiárida del Valle de Tehuacán-Cuicatlán (Puebla-Oaxaca). En particular esta publicación comprende la evaluación de la familia FABACEAE Subfamilia CERCIDOIDEAE. Actualmente se registra 1 género con 3 especies nativas, una de ellas endémica.
SOFRIMENTO: uma contribuição para o entendimento da ideação suicida a partir da fenomenologia da vida de Michel Henry
Authors: Gonçalves Divino José , Ferreira Leonardo Carrijo
Published: November 2022

The general objective of this work was to understand human suffering from the phenomenology of Michel Henry's life and to correlate it with suicide to understand the phenomena present in individuals who have suicidal ideation. The research process presented was classified as a bibliographic review, with a qualitative and descriptive approach, in the phenomenological perspective, basing its discussions on authors who approach this theme. This study becomes relevant due to the high number of individuals with suicidal ideation, in addition to the scarce bibliography on the subject between the two authors. The present study makes an important contribution to the understanding of suicide from the conception of suffering from Husserl and Michel Henry. Therefore, this study is relevant because, among many hardships of the historical, social and psychic condition of the individual itself. Suicide is a reality that refers to public and mental health, so it is of great importance to seek studies aimed at appropriate ways related to understanding the phenomena present in individuals who have suicidal ideation.
Komunikasi Politik Sultanah Safiatuddin Aceh
Authors: Rahmat Muarrief
Published: November 2022

The leadership of Sultanah Sri Ratu Safiatuddin has given birth to new values related to the presence of women in the power of the Kingdom of Aceh Darussalam. Through his policies, he has contributed greatly to a new perspective in the political history of Aceh. His collaborative policies have provided opportunities for everyone to be involved in the Aceh Darussalam government system regardless of background, especially gender. This paper attempts to unravel and analyze Ratu Safiatuddin's pattern of political communication regarding his policies that led to the trust of the Acehnese people at that time to be led. Among them include policies in the field of science and knowledge, strengthening the law, freedom of opinion, and gender equality. The results of this study show that through this policy the Queen can survive in a span of 35 years and even continues with three queens' leadership in the next period. Ratu has contributed new ideas for the fulfillment of the value of the existence of Islam and science.
KOMUNIKASI INSTRUKSIONAL PADA PROGRAM KESETARAAN PAKET C
Authors: Usman Ari , Yuningsih Ani , Triwardhani Ike Junita
Published: November 2022

Students in the high school equivalency program have their own uniqueness including: age, marital status, and socioeconomic status. They have experienced dropout and have not carried out learning activities for a long time. During the COVID 19 pandemic, most of the learning process takes place online, which is not easy for them. The research entitled "Instructional Communication in the High School Equivalency Program" intends to find out how the instructional communication model between tutors and students of the high school equivalency program in PKBM Patrakomala Bandung. The purpose was to analyze the interaction between tutors and students, the application of learning methods, the use of media, and the obstacles faced in the instructional communication process. This study uses a qualitative method with a case study approach. This study also uses constructivism theory from Jesse Delia. The results show that offline interactions are transactional, while online interactions are interactional. The learning methods used are: independent learning methods, assignments, lectures, and questions and answers. Tutors have full authority to determine the learning method to be used. The media used are seTARA Daring and WhatsApp groups. The obstacles encountered come from personal and situational variables of the students.
Diode Laser for the Management of Upper Tract Urothelial Cancer (UTUC) – Case Series.
Authors: Jimie Joachim , Kwok Abigail , Housami Fadi , Hussain Baher , Elfar Mahmoud
Published: November 2022

Background and Objective: Upper tract urothelial carcinoma (UTUC) is uncommon; however, at the time of diagnosis, they are usually more invasive than bladder urothelial carcinomas. Although nephroureterectomy (NU) has been the gold-standard treatment, guidelines have been set for kidney-sparing treatment in selected groups of patients. While these guidelines are aimed towards patients fit for salvage radical treatment, little has been published on managing the symptomatic patient not fit for NU. Various modalities of endoscopic ablation in managing UTUC have been described in the literature, but there is currently no reported use of the diode laser. Therefore, we aim to assess its efficacy and safety profile in the ablation of UTUC in patients unfit for major abdominal surgery in radical nephroureterectomy regardless of the tumour grade and size.

Patients and method A single centre retrospective review of patients who underwent Diode Laser treatment for UTUC over 4 years was done. Follow up through 6 monthly ureteroscopy alternating with computed tomography (CT) urogram was done to assess the need for further treatment.

Results: 30 patients were identified, with mean age 76 years (64-88) and variable tumour locations, including lower and mid ureter and renal pelvis, upper and lower calyces. 76.7% were ASA 3 and 20% ASA 4. The mean tumour size was 3.8 cm (2-7 cm). The mean number of sessions was 2.1 (1-6). 63.3% of the tumours were grade 2, while 30% were grade 3. A case of metastatic renal-cell carcinoma was diagnosed as a 4 cm filling defect in the kidney where the diode laser was used for resection biopsy and ablation. 16.7% experienced Clavien-Dindo grades 1-2 complications. A total of 6.7% of patients were converted to an inpatient stay. None of the patients needed blood transfusion nor did any develop a ureteric stricture on subsequent ureteroscopies. 48.3% of patients experienced clinical recurrences of which 57.1% were at a different site. Two of the patients developed metastatic disease. One patient died 3 years after initial treatment with disease progression.

Conclusion: The management of UTUC with diode laser is a safe and efficacious conservative treatment for disease and symptom control in patients unfit for radical treatment.
Approaches to mapping the soils’ thermal regime under the conditions of Transbaikalia’s contrasting relief
Authors: Balybina A.S. , Trofimova I.E.
Published: November 2022

Long-term temperature conditions of 3,2 m thick soil layer are studied based on the data of Transbaikalian weather stations. Among all the thermal factors, the most informative one, the smallest monthly mean temperature in the annual cycle at the standard measurement depth, is used. Its vertical profiles reflect the depth variations of the temperature and its spatial diversity. They constitute the base for a newly developed graphical classification scheme for wintery thermal conditions of soils. It includes five types of the thermal conditions
Analisis penyerapan tenaga kerja pada sektor pertanian di Kabupaten Tanjung Jabung Barat
Authors: Dewi Rezky Fatma , Prihanto Purwaka Hari , Edy Jaya Kusuma
Published: November 2022

Penelitian ini bertujuan untuk mengetahui kontribusi sektor pertanian terhadap penyerapan tenaga kerja total di Kabupaten Tanjung Jabung Barat, faktor-faktor apa saja yang mempengaruhi penyerapan tenaga kerja pada sektor pertanian di kabupaten Tanjung Jabung Barat. Data yang digunakan dalam penelitian adalah data sekunder (time series) dari tahun 2000-2013. Metode analisis yang  digunakan adalah Ordinary Least Square (OLS). Hasil  penelitian menemukan bahwa perkembangan penyerapan tenaga kerja sektor pertanian dengan rata-rata sebesar 8,06%, kontribusi sektor pertanian terhadap penyerapan tenaga kerja total dengan rata-rata sebesar 62,48%, faktor-faktor yang mempengaruhi peneyrapan tenaga kerja pada sektor pertanian yang terdiri dari pertumbuhan PDRB sektor pertanian dengan rata-rata 8,14%, potensi luas lahan dengan rata-rata -5,22%, upah minimum provinsi dengan rata-rata 15,89%, investasi dengan rata-rata 12,08 dan elastisitas penyerapan tenaga kerja pada sektor pertanian bersifat elastis yaitu sebesar 1,12%. Keempat variabel independen yaitu pertumbuhan PDRB sektor pertanian, potensi luas lahan, upah minimum provinsi dan investasi mempunyai pengaruh yang signifikan terhadap penyerapan tenaga kerja sektor pertanian. Secara parsial, Pertumbuhan PDRB sektor pertanian berpengaruh positif dan signifikan terhadap penyerapan tenaga kerja sektor pertanian, potensi luas lahan berpengaruh negatif dan signifikan terhadap penyerapan tenaga kerja sektor pertanian, upah minimum provinsi berpengaruh negatif dan signifikan terhadap penyerapan tenaga kerja sektor pertanian dan investasi berpengaruh positif dan tidak signifikan terhadap penyerapan tenaga kerja sektor pertanian di Kabupaten Tanjung Jabung Barat.
Pengaruh pendidikan, upah dan kesempatan kerja terhadap pengangguran terdidik di Provinsi Jambi
Authors: Fitri Fitri , Junaidi Junaidi
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh dari pendidikan, upah dan kesempatan kerja terhadap pengangguran terdidik di Provinsi Jambi. Data yang digunakan adalah data time series dari  tahun  2000-2015. Metode  analisis  data  adalah regresi Ordinary Least Square (OLS). Hasil penelitian  menunjukkan bahwa secara simultan, pendidikan, upah dan kesempatan kerja mempunyai pengaruh yang   signifikan terhadap pengangguran terdidik. Secara parsial, pendidikan berpengaruh positif dan kesempatan Kerja berpengaruh negatif terhadap pengangguran terdidik  di Provinsi Jambi, sedangkan upah tidak berpengaruh signifikan.
Analisis faktor-faktor yang mempengaruhi pendapatan industri rumah tangga pengolahan nanas (Studi Kasus Desa Tangkit Baru Kecamatan Sungai Gelam Kabupaten Muaro Jambi)
Authors: Rahayu Sri
Published: November 2022

Penelitian bertujuan untuk : (1). menganalisis kondisi sosial ekonomi industri rumah tangga pengolahan nanas di Desa Tangkit Baru Kecamatan Sungai Gelam Kabupaten Muaro Jambi; (2). menganalisis faktor-faktor yang mempengaruhi  pendapatan industri rumah tangga pengolahan nanas di Desa Tangkit Baru Kecamatan Sungai Gelam Kabupaten Muaro Jambi. Untuk menganalisis kondisi sosial ekonomi rumah tangga digunakan analisis deskriptif kuantitatif, dan untuk menganalisis faktor-faktor yang mempengaruhi  pedapatan industri rumah tangga pengolahan nanas digunakan analisis regresi berganda. Hasil analisis menemukan bahwa rata-rata pendapatan pengrajin industri pengolahan nanas Desa Tangkit sebesar Rp 9.357.864, dengan rata-rata produksi sebesar 494 Kg, biaya produksi rata-rata sebesar Rp 9.842.136 dan jam kerja rata-rata sebesar 86 jam kerja. Dari hasil pengujian regresi diperoleh bahwa variabel produksi dan jam kerja berpengaruh signifikan terhadap pendapatan pengrajin industri pengolahan nanas,  sedangkan variabel biaya produksi tidak berpengaruh signifikan Kata kunci : Pendapatan, Industri Pengolahan Nanas REFERENCES Anonim, 2005, Data Pertanian Tanaman Pangan dan Holtikultura 2004, Dinas Pertanian Pangan Jambi Anonim, 2008, Industri dan Klasisikasi industri, Dinas Perindustrian dan Perdagangan Provinsi Jambi Anonim, 2012, Muaro jambi Dalam Angka Tahun 2012, BPS, Muaro Jambi Anonim, 2014, Jumlah Industri Kecil dan Industri Rumah Tangga di Provinsi Jambi, Dinas perindustrian dan Perdagangan. Arikunto, Suharsimi. 2006. Prosedur Penelitian Suatu Pendekatan Praktik. Jakarta : Rineka Cipta Asni. N, 2006, Prospek Pengembangan Agroindustri Nenas tangkit di Provinsi Jambi, Jurnal Teknologi Hasil Pertanian, Vol V(1):47-50 Budiman, 2010, Analisis Pengaruh Pendapatan Terhadap Konsumsi Rumah Tngga Di Perumahan Garuda III Kecamatan Kota Baru, Skripsi FE- UNJA. Gujarati, Damodar. 2003. Econometric. Jakarta: Erlangga Hajrawati, 2005, Analisis Ekonomi Produksi Industri Pegoahan Nenas Di Desa Tangkit Baru, Skripsi FE – UNJA. Nainggolan,K. 2004, Strategi Kebijakan Pangan Traditional Dalam Rangka Ketahanan Pangan, Prosiding Seminar Balai Besar Penelitian dan Pengembagan Pasca Panen Pertanian.Bogor Naimah. Siti, 2011, Analisis Faktor – Faktor Yang Mempengaruhi Pendapatan Industri Rumah Tangga di Seberang Kota Jambi, Skripsi, FE – UNJA Octavia,Ade;Haryadi;Yulmardi dan Rahayu,Sri. (2011). Evaluasi Usaha Mikro Kecil dan Menengah Penerima Bantuan Pemerintah dan Strategi Peningkatan Daya Saing Usaha bersangkutan dalam rangka Mendorong Perekonomian Provinsi Jambi. DP2M
Analisis Faktor-Faktor yang Mempengaruhi Usaha Tani Padi Sawah Studi Kasus: Desa Pulau Pandan Kecamatan Limun Kabupaten Sarolangun
Authors: Ilmiyati Ilmiyati , Junaidi Junaidi , Bhakti Adi
Published: November 2022

The study aims to analyze : (1) characteristics of farmers and land rice farming in the Village of Pulau Pandan; (2) production and income of farmers in in the Village of Pulau Pandan; and (3) factors affecting the production of wet land paddy farming in the Village of Pulau Pandan.Based on the results of the research, it is known that simultaneously (factors) : the area of land, seeds, fertilizer, and pesticide have a significant effect or rice production in Pulau Pandan Village, and partially significant factor on rice production rice fields are land area and pesticide while seeds and fertilizer have no significant effect .the value of coefficient of determination is 0,960 which means the dependent variable (production) can be explained by the independent variable (land area, seeds, fertilizer, and pesticide) of 96% and the rest of 4% is explained by other variables not included in the model. The average income of paddy field farming is quite high for every planting season that is Rp. 19.317.480/Hectare
Analisis Faktor-Faktor yang Mempengaruhi Tingkat Pengangguran Terdidik di Provinsi Jambi
Authors: Rosalina Rosalina , Prihanto Purwaka Hari , Achmad Erni
Published: November 2022

This research aims to analyze the development of educated unemployment rates, education rate, economic growth, employment Rate and wages in Jambi Province and analyzed the effect of education rate, economic growth, employment rate and wages on the educated unemployment rate in Jambi Province. The data used is time series data from 2001-2016. This study uses descriptive analysis methods and quantitative analysis. The results showed that partially education rate and employment rate positive and significant influence on the educated unemployment rate in Jambi Province. While economic growth and wages has no effect on the educated unemployment rate in Jambi Province. Simultaneously the education rate, economic growth, employment rate and wages have a significant influence on the educated unemployment rate in Jambi Province.
Pengaruh Nilai Produksi, Investasi, dan PDRB Terhadap Penyerapan Tenaga Kerja Pada Industri Kecil di Kota Jambi
Authors: Junaidi Junaidi , Bhakti Adi , Vernanda Muhammad Azka
Published: November 2022

This research aims to find out and analyse the development value of GDRP, investment, production and absorption of labor in the city of Jambi as well as the influence of the value of production, investment and GDRP against labor absorption in the small city of industry Jambi. This type of research is explanatory research (research description). Where as to do hypothesis testing using linear regression equation itself multiple. The results of this study showed a good influence simultaneously or partially between production, investment and GDP against labor absorption in the small industry in the city of Jambi. Where the value of R2 which is 0.946 acquired for. That has meaning to the magnitude of the role or contribution of the variable the value of production, investment and GDRP was able to explain labor absorption in the small industry in the city of Jambi amounted to 94.6%. While the rest of 5.4% is affected by other factors that are not revealed in this study. This research suggests to maintain the condition of the economy that is stable then the Government must encourage sector agriculture and small business medium to keep growing because this sector is resistant to fluctuation and absorb the manpower in the amount large.
Pengaruh modal dan tenaga kerja terhadap nilai produksi industri pisang salai di Desa Purwobakti Kecamatan Bathin III Kabupaten Bungo
Authors: Istiqomah Luthvia , Umiyati Etik , Hardiani Hardiani
Published: November 2022

The purpose of this research is to analyze the socio-economic condition of salai (smoked) banana industry entrepreneur in Purwobakti Village. This research is a type of survey research. The method of analysis used is descriptive quantitative and qualitative. Based on the results of social analysis seen from the average age of entrepreneurs is 50 years, the average education level of high school graduates, the number of dependents of family members an average of four people and experience trying average for 12 years, while the economic conditions seen from the average production value at a rate of Rp. 10,125,000, the average initial capital of Rp. 1.737.500, the average raw material of Rp. 1,561,125, the average wage is Rp. 2,243,750 and the average workforce of four people. The variable of production and labor capital have a significant effect on the production value of salai banana industry in Purwobakti Village.  

Keywords: Production Capital, Labor, Industrial Production Value of Banana Sale  

Abstrak

Tujuan dari penelitian ini adalah untuk menganalisis kondisi sosial ekonomi pengusaha industri rumah tangga pisang salai di Desa Purwobakti. Penelitian ini merupakan jenis penelitian survey. Metode analisis yang digunakan adalah deskriptif kuantitatif dan kualitatif. Berdasarkan hasil analisis sosial dilihat dari umur rata-rata pengusaha adalah 50 tahun, tingkat pendidikan rata-rata tamatan SMA, jumlah tanggungan anggota keluarga rata-rata empat orang dan pengalaman berusaha rata-rata selama 12 tahun, sedangkan kondisi ekonomi dilihat dari nilai produksi rata-rata sejumlah Rp. 10.125.000, modal awal rata-rata sejumlah Rp. 1.737.500, bahan baku rata-rata sejumlah Rp. 1.561.125, upah rata-rata sejumlah Rp. 2.243.750 dan jumlah tenaga kerja rata-rata sebanyak empat orang. Modal produksi dan tenaga kerja berpengaruh signifikan terhadap nilai produksi industri pisang salai di Desa Purwobakti..

Kata kunci : Modal Produksi, Tenaga Kerja, Nilai Produksi Industri Pisang salai
Pengaruh PDRB, Upah Minimum Provinsi dan Pengeluaran Pemerintah Terhadap Penyerapan Tenaga Kerja di Provinsi Jambi
Authors: Ziyadaturrofiqoh Ziyadaturrofiqoh , Zulfanetti Zulfanetti , Safri Muhammad
Published: November 2022

This study aims to analyze the effect of GRDP, Provincial Minimum Wage, government expenditure on employment in Jambi Province during the period of 1997-2015. The type of data used in this study is secondary data. The results of this study found that simultaneously GRDP, provincial minimum wage, government expenditure has a significant effect on the employment in Jambi Province. The coefficient of determination (R2) shows that the independent variables studied are able to explain 91 percent of the employment and the remaining 9 percent are explained by other variables that are not examined. Partially PDRB significantly influence the employment in Jambi Province. While the Provincial Minimum Wage and Government expenditure did not affect the employment in Jambi Province.

Keywords: Employment, GRDP, Wage, Government  Expenditure

Abstrak

Penelitian ini bertujuan untuk menganalisis  pengaruh PDRB, Upah Minimum Provinsi (UMP), pengeluaran pemerintah terhadap penyerapan tenaga kerja di Provinsi Jambi selama kurun waktu 1997-2015. Jenis data yang digunakan dalam penelitian ini adalah data sekunder. Hasil penelitian ini menunjukan bahwa secara simultan PDRB, UMP, Pengeluaran Pemerintah berpengaruh signifikan terhadap penyerapan tenaga kerja di Provinsi Jambi periode 1997 – 2015. Koefisien determinasi (R2) menunjukan bahwa variabel bebas yang diteliti mampu menjelaskan 91 persen terhadap penyerapan tenaga kerja dan sisanya 9 persen dijelaskan oleh variabel lainnya  yang tidak diteliti. Secara parsial PDRB berpengaruh signifikan terhadap penyerapan tenaga kerja di Provinsi Jambi, sedangkan UMP dan pengeluaran pemerintah tidak berpengaruh signifikan.

Kata kunci : Penyerapan Tenaga Kerja ,PDRB, Upah, Pengeluaran   pemerintah
Analisis pengaruh pertumbuhan penduduk, pendidikan, pertumbuhan ekonomi, pengeluaran pemerintah, tingkat pengangguran dan inflasi terhadap tingkat kemiskinan di Kota Jambi
Authors: Lestari Dira Puji , Junaidi Junaidi , Aminah Siti
Published: November 2022

This research entitled “Analyzing the affect of  population growth, education, economic growth, government expenditure, unemployment rate and inflation towards the poverty rate of Jambi city”. The purpose of this research were to analyze the population growth, education, economic growth, government expenditure, unemployment rate, inflation and  the poverty rate and to analyze the affect of  population growth, education, economic growth, government expenditure, unemployment rate, and inflation towards the poverty rate of Jambi city.This research used ordinary least squares. The F test indicated that simultaneously the variables of the population growth, education, economic growth, government expenditure, unemployment rate, and inflation significantly affected the poverty rate of Jambi city. While t test revealed that partially education, government expenditure, unemployment rate and inflation affected the poverty rate of Jambi city. Meanwhile, the variables of population growth and economic growth insignificant to the poverty rate of Jambi city.
Determinan pendapatan driver Go-Jek di Kota Jambi
Authors: Mardatillah Mutiara , Junaidi Junaidi , Umiyati Etik
Published: November 2022

The purpose of this study was to determine the socio-economic conditions of Go-Jek drivers and the effect of working hours, work experience, age, education and number of passengers on the income of Go-Jek drivers in Jambi City. The data used are primary data obtained from questionnaires and direct interviews with a sample of 98. The sampling method used was incidental sampling. The data analysis tool used is descriptive and quantitative analysis with multiple linear analysis. The socio-economic conditions of Go-Jek drivers in Jambi City are known that the average age is 29 years. The average sex is male. The average marital status is not married. The average education is high school / equivalent. The average number of dependents is 2 people. The average job status is the main. The average side business is in the service sector. The average expenditure for operational costs is for fuel costs, pulses and internet costs, vehicle maintenance costs. The average expenditure for food consumption is for rice and non-rice. The average expenditure for non-food consumption is for education costs, health costs, clothing and others. The simultaneous results of multiple linear regression analysis that the income of Go-Jek drivers in Jambi City is influenced by working hours, work experience, age, education and number of passengers . While partially working hours, work experience, age, college education and number of passengers are significant influences on the income of Go-Jek drivers, while high school education has no significant effect.
Analisis pajak penerangan jalan dan pengaruhnya terhadap sektor listrik, gas, dan air di Kabupaten Tanjung Jabung Barat
Authors: Hakiki Nur , Mustika Chandra , Zamzami Zamzami
Published: November 2022

The purpose of this study is to analyze the street lighting tax and its effect on the gas and water electricity sector in Tanjung Jabung Barat District. In addition, the authors identified the development and tax contribution of street lighting. Tanjung Jabung Barat Regency, the level of effectiveness of street lighting tax in tanjung jabung barat district and the influence of street lighting tax output on the electricity, gas and water sector in the West Tanjung Jabung Regency. This study used secondary data from the period 2006 to 2013. The data analysis method used in the study this is a descriptive quantitative method with regression analysis in interpolation data. In terms of its contribution to Regional Original Revenue
Faktor-faktor yang mempengaruhi niatan migran untuk menetap di Kota Jambi
Authors: Diana Fera , Junaidi Junaidi , Edi Jaya Kusuma
Published: November 2022

This study aims to: 1) Identify the conditions of migrants in Jambi City, and 2) Analyze the factors that influence the intention of migrants to stay in Jambi City. The method used in this study is quantitative descriptive, using primary data obtained by interview. Based on the identification of 98 respondents, they were dominated by migrants with male sex aged 20-29 years, were married and lived in a contract/ rent house. Estimated results of Binary Logistic Regression, simultaneously shows a significant influence between the intention of migrants to stay in Jambi City with the variables in the model. While partially, the intention of migrants to stay in Jambi City is influenced by gender variables, higher education level variables, marital status variables, home ownership status variables and income variables. Age variable, high school / equivalent education level variable and variable workplace distance from the origin region is not significant to the intention of migrants to stay in Jambi City.
Strategi Perang Menurut Hukum Humaniter Internasional: Legalkah Metode Blokade?
Authors: Jazirah Hardinna Putri , Tuhulele Popi , Riry Welly Angela
Published: November 2022

Artikel ini membahas mengenai legalitas penggunaan metode blokade dalam konflik bersenjata dan implikasi hukumnya sebagai suatu strategi perang menurut Hukum Humaniter Internasional. Tujuan dari penulisan ini adalah untuk mengetahui bagaimana penggunaan blokade yang bersifat legal dan implementasinya sesuai dengan Hukum Humaniter. Sebagai suatu metode perang, blokade sering digunakan dalam konflik bersenjata menjadi suatu metode yang tidak sesuai dengan sumber Hukum Internasional karena dapat menyebabkan kerugian dan korban jiwa.  Padahal ada banyak regulasi yang mengatur mengenai blokade diantaranya Declaration of Paris 1856 yang menjelaskan mengenai efektifitas blokade, Declaration of London 1909 yang mengatur mengenai penjaminan hak-hak negara netral, Konvensi Jenewa 1949 yang juga mengatur ketentuan mengenai pengiriman bantuan kemanusiaan pada saat blokade di daerah konflik, dan San Remo Manual 1994 mengatur mengenai  syarat sah diterapkan blokade. Selain itu, regulasi ini juga kerap digunakan para ahli hukum untuk mengemukakan pendapatnya mengenai blokade sehingga  menjadi sumber acuan primer para hakim untuk menemukan hukum. Oleh sebab itu, untuk melengkapi ketentuan blokade, diperlukan peran organisasi internasional untuk memberikan pengawasan, pemberian sanksi yang tegas serta pentingnya  komitmen  negara  pihak dalam menerapkan metode blokade.
Predictors for Invasive Home Mechanical Ventilation Duration in Chronic Lung Disease of Prematurity
Authors: Foster Carolyn , Noreen Paige , Grage Jennifer , Kwon Soyang , Hird-McCorry Lindsey P. , Janus Angela , Davis Matthew M. , Goodman Denise , Laguna Theresa
Published: November 2022

Background Children with chronic lung disease (CLD) of
prematurity who require invasive home mechanical ventilation (iHMV) are
medically vulnerable and experience high caregiving and healthcare
costs. Predictors for duration of iHMV remain unclear, which can make
prognostication and decision-making challenging. Methods A
retrospective cohort study of children with CLD of prematurity requiring
invasive iHMV was conducted from an independent children’s hospital
records (2005-2021). The primary outcome was iHMV duration, defined as
time from initial discharge home on iHMV until cessation of positive
pressure ventilation (day and night). Two new variables were included:
corrected tracheostomy age (CTA) (chronological age at discharge minus
age at tracheotomy) and level of ventilator support at discharge (minute
ventilation per kg per day). Univariable Cox regression was performed
with variables of interest compared to iHMV duration. Significant
nonlinear factors (P<0.05) were included in the multivariable
analysis. Results One-hundred-and-nineteen patients used iHMV
primarily for CLD of prematurity. Patient median index hospitalization
lasted 12 months (IQR 8.0,14.4). Once home, half of patients were weaned
off iHMV by 36.0 months and 90% by 52.2 months. Being Hispanic/Lantix
ethnicity (HR 0.14 (95% CI 0.04, 0.53), p<0.01) and having a
higher CTA were associated with increased iHMV duration (HR 0.66 (CI
0.43, 0.98), p<0.05). Conclusions Disparity in iHMV
duration exists among patients using iHMV after prematurity. Prospective
multisite studies that further investigate new analytic variables, such
as CTA and level of ventilator support, and address standardization of
iHMV care are needed to create more equitable iHMV management
strategies.
Contrasting leaf thickness and saturated water content explain wide-ranging air/water fractions, nutrient contents, and water-use efficiency among arid succulents
Authors: Lamont Byron , Lamont Heather C.
Published: November 2022

Eight species in the Namib Desert, South Africa were assessed for their
leaf area ( A), thickness ( z), saturated ( Q) and
dry mass, relative volume of air ( F), water
and dry mass, intrinsic water-use efficiency (based on δ
C), and N, P and cation (Na+K) contents. As
water-storage capacity is a function of Q and
z, this means Q/ A (= Q •
z) is an ideal index of succulence compared with
specific-leaf-area and other indices that highlight mass rather than
volume. Specific gravity ( ρ) has a different
relationship with the F of sclero-mesophylls:
rising ρ infers decreasing air content is
replaced by water rather than dry matter. The trend among succulent
species, including Argentinian/Spanish added to our study, was Q/
A exceeding 1 mg water/mm whose overall slope
was ten times that for co-occurring sclerophyll-mesophyll species, and
shows the futility of seeking a universal relationship among plants
regarding their water-storing properties. (Na+K), N and P concentrations
varied on a dry-matter, but not water-volume, basis. W relationships were essentially functions of variations
in z and increased metabolic efficiency. We conclude that
z and Q are keys to the special
physiological properties of succulent leaves. Adding succulents would
force many current monotonic relationships to dichotomize.
A case of post-COVID-19 myalgic encephalomyelitis/chronic fatigue syndrome characterized by post-exertional malaise and low serum acylcarnitine level
Authors: Jinushi Ryuhei , Nishiguchi Shou , Masuda Sakue , Sasaki Akiko , Koizumi K , Ryozawa Shomei
Published: November 2022

COVID-19 afflicts patients with acute symptoms and longer-term sequelae.
One of the sequelae is myalgic encephalomyelitis/chronic fatigue
syndrome (ME/CFS), which is often difficult to diagnose, having no
established tests. In this article, we synthesize information from
literature reviews on patients with ME/CSF that developed after recovery
from COVID-19.
Critical Care Needs and Outcome of Pediatric T cell Lymphoblastic Leukemia or Lymphoma with Superior Venacaval Syndrome
Authors: Yadav Satya , Upasana K , Thakkar Dhwanee , Yadav Anjali , Arora Sunisha , Rastogi Neha
Published: November 2022

Background- Superior Vena Cava Syndrome (SVCS) is a
life-threatening oncological emergency affecting children with T-cell
Acute lymphoblastic Leukemia (T-ALL)/ T-Lymphoblastic Lymphoma (T-LBL).
This can prove fatal if not managed appropriately and promptly.
Method- We describe critical care needs and outcome of
T-ALL/T-LBL patients managed in our unit from 1 May
2016 to 31 March 2021. Result-
Twenty-three of the 120 pediatric ALL/LBL patients (19%) managed in our
unit had T-ALL/T-LBL. Eleven (48%) patients presented with SVCS. All
presented with cough and dyspnea. Chest X-Ray showed mediastinal
widening in all patients. Flow cytometry in various body fluids could
reach prompt diagnosis in 90% patients and mass biopsy was performed in
only 1 patient. Eight patients required Pediatric Intensive Care Unit
support. All 11 patients were started on corticosteroids soon after
diagnosis of SVCS. The median time to symptom relief was 4 days and that
for significant improvement on X-ray was 7days. At a median follow up of
23-months (6-63 months) overall survival and event-free survival was
75%. Conclusion- T-ALL/T-LBL patients with SVCS with good
critical care can have improved outcomes. Prompt therapeutic
interventions like pericardiocentesis can be life-saving. Flow cytometry
can be a handy tool for quick diagnosis and help avoid invasive
procedures in sick patients.
Venetoclax dose adjustment due to drug-drug interactions: A case report and literature review
Authors: Fan Weibin , Guo Jun , Zhang Yue , Zhang Runcong , Lin Bin
Published: November 2022

The primary aim of the study is to discuss the potential interactions
between venetoclax and common drugs used in department of hematology and
the corresponding effects on the efficacy and safety of venetoclax
treatment. Here, we report an acute myeloid leukemia patient treated
with venetoclax and posaconazole, and the dose of venetoclax was
adjusted due to drug interactions. Clinical pharmacists actively
participated in treatment of this patient to provide pharmacy care to
assist clinicians to identify the venetoclax-induced liver function
impairment and give timely management. The case reported here is hoped
to provide reference for clinical venetoclax treatment in patients with
such disease. Clinical pharmacists should actively participate in
clinical treatment, actively screen potential drug interactions,
strengthen cooperation and communication with doctors, provide patients
with high-quality pharmaceutical services, and establish clinical
pharmacists’ status in the multidisciplinary treatment of tumor.
Non-eosinophilic asthma in nonsteroidal anti-inflammatory drug exacerbated respiratory disease
Authors: Sanak Marek , Mastalerz Lucyna , Celejewska-Wójcik Natalia , Ćmiel Adam , Wójcik Krzysztof , Szaleniec Joanna , Hydzik-Sobocińska Karolina , Tomik Jerzy
Published: November 2022

Background: The cellular inflammatory pattern of nonsteroidal
anti-inflammatory drug–exacerbated respiratory disease (N-ERD) is
heterogeneous. However, data on the heterogeneity of non-eosinophilic
asthma (NEA) with aspirin hypersensitivity are scanty. By examination of
N-ERD patients based on clinical data and eicosanoid biomarkers we aimed
to identify NEA endotypes potentially guiding clinical management.
Methods: Induced sputum was collected from 133 patients with
N-ERD. Sixty six patients (49.6%) with NEA were included in the
hierarchical cluster analysis based on clinical and laboratory data. The
quality of clustering was evaluated using internal cluster validation
with different indices and a practical decision tree was proposed to
simplify stratification of patients. Results: The most frequent
NEA pattern was paucigranulocytic (PGA; 75.8%), remaining was
neutrophilic asthma (NA; 24.2%). Four clusters were identified. Cluster
#3 included the highest number of NEA patients (37.9%) with severe
asthma and PGA pattern (96.0%). Cluster #1 (24.2%) included severe
only asthma, with a higher prevalence of NA (50%). Cluster #2 (25.8%)
comprised well-controlled mild or severe asthma (PGA; 76.5%). Cluster
#4 contained only 12.1% patients with well-controlled moderate asthma
(PGA;62.5%). Sputum prostaglandin D levels
distinguished cluster #1 from the remaining clusters with an area under
the curve of 0.94. Conclusions: Among identified four NEA
subtypes, clusters #3 and #1 represented N-ERD patients with severe
asthma but a different inflammatory signatures. All the clusters were
discriminated by sputum PGD levels, asthma severity,
and age of patients. The heterogeneity of non-eosinophilic N-ERD
suggests a need for novel targeted interventions.
Efficacy and Safety of targeted therapy Inhibitors for RET-driven Solid Cancer: A Systematic Review and Meta-analysis
Authors: Li Guoli , Chen Yufan , Wei Keyang , Deng Honghao , Chen yanfeng
Published: November 2022

Advanced and metastatic RET-driven solid cancer is not susceptible to
chemotherapy or radiotherapy. The development of targeted therapy has
led to a new therapeutic model. Nevertheless, no systematic evaluation
of their efficacy and safety has been carried out in RET-driven solid
cancer. Systematic review and single-arm meta-analysis were performed.
Four electronic databases were searched (PubMed, Embase, Cochrane
Library, and Web of Science) from each database’s inception date until
February 27, 2022. Study inclusion criteria focused on peer-reviewed
published articles that reported the efficacy and safety of targeted
therapy Inhibitors for RET-driven Solid Cancer, excluding case
reports/series, review papers, meta-analyses, organizational guidelines,
editorial letters, expert opinions, and conference abstracts. 15
randomized, locally advanced or metastatic RET-driven solid cancer
assays (n=1835) were included. Previously untreated with RET-Specific
Tyrosine Kinase Inhibitors(TKI) group showed the highest objective
remission rate(ORR) (0.75,95%CI=0.68-0.82) or disease control rate(DCR)
(0.96,95%CI=0.92-0.99), and lower dose reduction(34.8%) or
discontinuation(3.4%), but the performance of general adverse reactions
(Grade1-5 96.8%, Grade3-5 69.2%) were not as good as Multi-Target
Tyrosine Kinase Inhibitors (MKI) group, followed by previously
treated/untreated with MKI/TKI group (MIX group). Targeted therapy
inhibitors have significant efficacy in RET-driven solid cancer therapy.
The ORR, DCR parameters and adverse reaction of TKI are better than
those of MKI. It was also related to the patient’s previous treatment
status. The ORR/DCR of the patients who received no targeted therapy was
superior to those who received Vandetanib or Cabozantinib as first-line
therapy.
Drug-Drug Interaction Potential of SH-1028, a Third-generation EGFR-TKI: In Vitro and Clinical Trials
Authors: Li Xiaoli , Liu yuyan , Xu Yuanyuan , Ding Jiaxiang , Su Yue , He Cuixia , Zhu Minhui , Zhao Xiangdi , Wang Ying , Shan Rongfang , Liu Yuanyuan , Liu Bingyan , Xie Jing , Guo Fei , Ding Yuzhou , Zhou Huan , Wang Zhiqiang , Li Hongtao
Published: November 2022

SH-1028 is an irreversible third-generation EGFR tyrosine kinase
inhibitor (EGFR-TKI) for the treatment of locally advanced or metastatic
non-small cell lung cancer (NSCLC). Considering the possibility of
combination therapy in patients with NSCLC, we investigated the
drug-drug interaction (DDI) potential of SH-1028 both in vitro and in
clinical trials. The in vitro studies were conducted to determine the
potential of SH-1028 as a substrate, inducer, or inhibitor of cytochrome
P450 (CYP) subtypes. A phase I drug-drug interaction study in healthy
volunteers was performed to evaluate the impact of co-administering
rifampicin (a strong CYP3A4 inducer) and itraconazole (a strong CYP3A4
inhibitor) on the pharmacokinetics of SH-1028. The in vitro experiments
showed that SH-1028 was mainly metabolized by CYP3A4. The activities of
CYP1A2, 2B6, 2C19, 2D6 and 3A4 enzymes were slightly inhibited in vitro
with SH-1028. SH-1028 has no obvious induction effect on CYP1A2 and
CYP2B6 activities, but has potential induction effect on CYP3A4 mRNA
expression. However, SH-1028 may not induce or inhibit human CYPs
significantly at the clinically expected dose (200 mg). It is speculated
that itraconazole and rifampicin affect the metabolism of SH-1028. In
the clinical application of SH-1028, special attention should be paid to
the interaction between SH-1028 and drugs or foods that affect the
activity of CYP3A4.
Study on Changes of Ecosystem Services Value and Driving Factors in Yellow River Delta
Authors: Hou Jiaping , Zhang Jianing , Duan Yeqing , Zhou Shenbei
Published: November 2022

Wetlands are precious natural resources with huge ecosystem services
value behind them. Understanding the temporal and spatial variation of
wetland ecosystem services value and its driving forces is essential for
sustainable development and human well-being. Taking the Yellow River
Delta as an example, this article calculated ecosystem services values
based on equivalent factor method from 2000 to 2020 and analyzed the
spatiotemporal characteristics of ecosystem services value by spatial
statistics analysis; used Geodetector to detect and interact with the
driving factors. The results show the following: (1) The reduction of
wetland area directly caused the reduction of ecosystem services value,
and the distribution of ecosystem services value in the wetland area
shows agglomeration phenomenon. (2) NDVI, GDP and humidity were the main
driving factors affecting the change of ecosystem services value, while
elevation, slope and aspect had little effect. (3) The main factors
affecting the ecosystem services value are all related to vegetation.
(4) When temperature, NDVI, precipitation, humidity, GDP and population
density interacted, they had a greater effect on ESV than when they
acted alone. Our research results can provide reference information for
the world’s delta regions and provide scientific advice for ecological
environment governance to promote the healthy development of the
ecological environment.
Metabolic constraints on the body size scaling of extreme population densities
Authors: Segura Angel , Perera Gonzalo
Published: November 2022

Pest outbreaks, harmful algal blooms, and population collapses are
extreme events with critical consequences for ecosystems, highlighting
the importance of deciphering the driving ecological mechanisms
underlying extreme events. By combining the generalized extreme value
(GEV) theory from statistics and the hypothesis of a resource-limited
metabolic restriction to population abundance, we evaluated theoretical
predictions on the size-scaling and variance of extreme population
abundance. Phytoplankton data from the L4 station in the English Channel
showed a negative size scaling of the expected value of maxima, whose
confidence interval included the predicted metabolic scaling (a = –1).
We showed a humped pattern in variance with maxima at intermediate
sizes. These results are consistent with the bounded abundance of
small-sized populations that are subjected to strong grazing and with
the expected decrease in variance towards large sizes. This approach
provides unbiased return times, thereby improving the prediction
accuracy of the timing of bloom formation, and describes a coherent
framework in which to explore extreme population densities in natural
communities.