bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Coronary Computed Tomography Angiography in the Diagnosis, Risk Stratification, and Management of Patients with Diabetes and Chest Pain
Authors: van de Vijver Willem R. , Hennecken Jasper , Lagogiannis Ioannis , Pérez del Villar Candelas , Herrera Cristian , Douek Philippe C , Segev Amit , Hovingh G. Kees , Išgum Ivana , Winter Michiel M. , Planken R. Nils , Claessen Bimmer E.P.M.
Published: December 2024

Coronary artery disease (CAD) affects over 200 million individuals globally, accounting for approximately 9 million deaths annually. Patients living with diabetes mellitus exhibit an up to fourfold increased risk of developing CAD compared to individuals without diabetes. Furthermore, CAD is responsible for 40 to 80 percent of the observed mortality rates among patients with type 2 diabetes. Patients with diabetes typically present with non-specific clinical complaints in the setting of myocardial ischemia, and as such, it is critical to select appropriate diagnostic tests to identify those at risk for major adverse cardiac events (MACEs) and for determining optimal management strategies. Studies indicate that patients with diabetes often exhibit more advanced atherosclerosis, a higher calcified plaque burden, and smaller epicardial vessels. The diagnostic performance of coronary computed tomographic angiography (CCTA) in identifying significant stenosis is well-established, and as such, CCTA has been incorporated into current clinical guidelines. However, the predictive accuracy of obstructive CAD in patients with diabetes has been less extensively characterized. CCTA provides detailed insights into coronary anatomy, plaque burden, epicardial vessel stenosis, high-risk plaque features, and other features associated with a higher incidence of MACEs. Recent evidence supports the efficacy of CCTA in diagnosing CAD and improving patient outcomes, leading to its recommendation as a primary diagnostic tool for stable angina and risk stratification. However, its specific benefits in patients with diabetes require further elucidation. This review examines several key aspects of the utility of CCTA in patients with diabetes: (i) the diagnostic accuracy of CCTA in detecting obstructive CAD, (ii) the effect of CCTA as a first-line test for individualized risk stratification for cardiovascular outcomes, (iii) its role in guiding therapeutic management, and (iv) future perspectives in risk stratification and the role of artificial intelligence.
Intravascular Ultrasound Guiding Percutaneous Coronary Interventions in Complex Higher Risk-Indicated Patients (CHIPs): Insight from Clinical Evidence
Authors: Viana Sidonio Mesquita , Zhang Dai-Min
Published: December 2024

Intravascular ultrasound (IVUS) in percutaneous coronary intervention (PCI) has transformed the management of complex higher risk-indicated patients (CHIPs), representing a pivotal advancement in high-risk procedure navigation. IVUS, complementing conventional angiography, provides unparalleled insights into lesion characteristics, plaque morphology, and vessel structure, enhancing the precision of stent placement and postprocedural care for CHIPs. The ongoing trials underscore the pivotal role of IVUS in optimizing procedural accuracy and improving clinical outcomes for high-risk patients, promising exciting new findings. However, notable gaps persist, encompassing the absence of standardized IVUS protocols, cost implications, and limited integration into routine practice. This study aims to address these gaps comprehensively by further delineating the influence of IVUS on patient outcomes, procedural success, and long-term prognostic indicators. This review aims to provide a clear overview of IVUS-guided PCI in CHIP, highlighting the significance of ongoing trials, identifying prevalent challenges, and outlining the objective of narrowing these gaps.
Drug-Coated Balloons versus Drug-Eluting Stents for the Treatment of De Novo Coronary Artery Disease: A Meta-Analysis of Randomized Controlled Trials
Authors: Niu Jialong , Wang Kexin , Wang Wenjie , Liu Yixuan , Yang Jiaxin , Sun Yan , Wang Furong , Gao Wen , Ge Hailong
Published: December 2024

Background: Because of the limitations in new-generation drug-eluting stents (DES), treatments advocating for non-stents with a drug-coated balloon (DCB) is now of great interest. Here, we conducted a meta-analysis to testify whether a DCB was more effective and safer than a DES in treating de novo coronary artery disease (CAD). Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science to obtain high-quality trials comparing DCB with DES for the treatment of de novo CAD. The primary endpoint was target lesion revascularization (TLR), and the secondary endpoints were in-lesion late lumen loss (LLL), all-cause death, myocardial infarction and binary restenosis. Results: We enrolled 1661 patients from seven randomized clinical trials. Compared with the DES group, the MD (mean difference) of in-lesion LLL was significantly lower in the DCB group (MD –0.19, 95% CI –0.23 to –0.16, p < 0.00001, I2 = 0%). The DCB group showed superiority in small vessel disease (SVD) in in-lesion LLL (MD –0.21, 95% CI –0.34 to –0.08, p = 0.001). Conclusions: The DCB group exhibited a lower in-lesion LLL compared to the DES group, and DCB was not inferior to DES in other endpoints, including in the SVD subgroup. Hence, to our knowledge, DCB is non-inferior to DES for de novo CVD and SVD. DCB in patients with CVD needs further large and long-term clinical trials to demonstrate its long-term efficacy. The PROSPERO Registration: CRD42021268965, https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=268965.
The Cardiomyocyte in Cirrhosis: Pathogenic Mechanisms Underlying Cirrhotic Cardiomyopathy
Authors: Ryu Dae Gon , Yu Fengxue , Yoon Ki Tae , Liu Hongqun , Lee Samuel S.
Published: December 2024

Cirrhotic cardiomyopathy is defined as systolic and diastolic dysfunction in patients with cirrhosis, in the absence of any primary heart disease. These changes are mainly due to the malfunction or abnormalities of cardiomyocytes. Similar to non-cirrhotic heart failure, cardiomyocytes in cirrhotic cardiomyopathy demonstrate a variety of abnormalities: from the cell membrane to the cytosol and nucleus. At the cell membrane level, biophysical plasma membrane fluidity, and membrane-bound receptors such as the beta-adrenergic, muscarinic and cannabinoid receptors are abnormal either functionally or structurally. Other changes include ion channels such as L-type calcium channels, potassium channels, and sodium transporters. In the cytosol, calcium release and uptake processes are dysfunctional and the myofilaments such as myosin heavy chain and titin, are either functionally abnormal or have structural alterations. Like the fibrotic liver, the heart in cirrhosis also shows fibrotic changes such as a collagen isoform switch from more compliant collagen III to stiffer collagen I which also impacts diastolic function. Other abnormalities include the secondary messenger cyclic adenosine monophosphate, cyclic guanosine monophosphate, and their downstream effectors such as protein kinase A and G-proteins. Finally, other changes such as excessive apoptosis of cardiomyocytes also play a critical role in the pathogenesis of cirrhotic cardiomyopathy. The present review aims to summarize these changes and review their critical role in the pathogenesis of cirrhotic cardiomyopathy.
Evaluation of 8-Oxoguanine DNA Glycosylase-1(OGG1) Serum Levels in Patients with Type2 Diabetes Mellitus
Authors: Al-dulaimi Duaa Hussein Allawi
Published: December 2024

: Chronic hyperglycemia in type 2 diabetes mellitus leads to elevated oxidative stress. As a consequence, the accumulation of reactive oxygen species (ROS)may cause additional damage to various biological macromolecules, including DNA. The current study aims to evaluate the DNA damage in type2 diabetic patients from Wasit Province by estimating the levels of 8-OHdG using ELISA. All samples were collected from the local community of Wasit province, Iraq.  Forty-five type 2 diabetes mellitus patients (22 males and 23 females) and 35 healthy controls (17 males and 18 females) were genotyped for 8-oxoguanine DNA glycosylase-1(OGG1). Determination of 8-oxoguanine DNA glycosylase-1(OGG1) in sera of patients with T2DM and controls was done by using an Enzyme-linked immunosorbent assay ELISA.The results reveal highly significant differences, the OGG1 levels in the diabetic patients were higher than that of controls (646.96±2.14), controls (326.01±16.66), P= 0.0001. The OGG1 levels were elevated significantly among males and female’s patients withT2DM compared to the control group, 627.02±66.31 versus 679.68±63.27),        P= 0.01 (381.85±29.33 versus 355.44±31.45), P = 0.0006, respectively. No significant differences were observed when comparing OGG1 levels between male and female patients with type2 diabetes, as well as in the control group: 627.03±66.31 versus 679.68±63.27, P=0.5974;381.85±29.36 vs.355.44±31.45, P=0.5478 in patients and controls respectively.679.68267±63.27413 versus627.02830±66.29612 with a non-significant difference P=0.5974. In conclusion levels of serum OGG1 are associated with diabetes mellitus
Theoretical investigations on the Energy gap, UV- Vis Spectrum and Thermochemical Properties of PVA doped with ZnO andTiO2
Authors: Jawad Huda M.
Published: December 2024

Different polymers have attractive multiple properties due to their uses in many fields. The synthesized polymer polyvinly alcohol (PVA) with metal oxide nanoparticles has many applications in different approaches, such as electronics, sensors, optical,  optoelectronics, and biomedical fields.  The study was carried out within the framework of density functional theory  with B3LYP and exchange- correlation energy functionals 6-31G(d, p).  Three compounds  were PVA and PVA synthesized with zinc oxide (ZnO) and Titanium dioxide (TiO2) nanocomposites. The results proved  that using these oxides is a good way to improve the electronic properties of PVA as the energy gap of PVA decreased from 3.8 to 3.4 eV and 3.3 eV PVA/TiO2 and PVA/ZnO, respectively. This demonstrates the good semiconductor character of these compounds with applications related to solar cell manufacturing. The  photosensitivity of both PVA/TiO2 and PVA/ZnO  samples in FTIR and UV-Vis results indicated that TiO2 and ZnO  interacted strongly with PVA. So they can be used in other applications, such as energy storage capacitors. The vibrational mode were then analyzed in terms of force constant and reduced mass, which were relatively constant hydrogen vibrations.
Synthesis, Structural Investigation and Biological Activity of a Heterocyclic Schiff-Base Ligand and Its Coordination Complexes
Authors: Al-Rubaye Baidaa
Published: December 2024

This study reports the formation, characterisation and biological evaluation of a Schiff base ligand and its corresponding metal complexes. The Schiff base ligand (HL) was prepared through a condensation reaction involving isonicotinohydrazide and N'-((1R,2R,4R,5S, E)-2,4-bis(4-chlorophenyl)-3-azabi cyclo[3.3.1]nonan-9-ylidene) isonicotinohydrazide (M) in EtOH solvent and (3-5) drops of conc. HCl. The interaction of HL with selected metal chlorides including Mn(+2), Co(+2), Ni(+2), Cu(+2) and Zn(+2) in a 2:1 (L:M) mole ratio resulted in the synthesis of complexes with the general formula [M(HL)Cl2] (where: M = Mn(+2),Co(+2) and Ni(+2)) and [M`(HL)Cl2] (where M` =  Cu(+2) and Zn(+2)). The characterisation of the prepared compounds was carried out using a range of spectroscopic analyses, containing FT-IR and electronic spectroscopy, NMR (1H and 13C), mass spectrometry, atomic absorption, as well as a range of analytical techniques to fully characterise the title compounds, including elemental microanalysis (C.H.N) for elemental composition determination, chloride percentage analysis, conductivity measurements to assess electrical conductivity in solution, magnetic moments to investigate the magnetic properties and melting point determination. These spectroscopic and analytical techniques were involved in validating the identity and structural properties of both the ligand and its corresponding coordination compounds. Besides the structural characterisation, the biological evaluation of the synthesised compounds toward both G+ and G- bacterial strains was assessed. This investigation sheds light on the potential applications of these compounds in combating bacterial infections.
Automated Malaria Detection Using Convolutional Neural Networks and Machine Learning
Authors: Lateef Albukhnefis Adel
Published: December 2024

ABSTRACT: Millions of people suffer from malaria, considered one of the most dangerous parasitic diseases threatening human life, especially in tropical and subtropical regions. There are many challenges in using traditional diagnostic methods such as blood smear checking, which can be achieved by using a microscope due to the inaccuracy of manual analysis and reliance on individual skills. Therefore, utilizing machine learning or deep learning algorithms for automating malaria detection provides encouraging solutions to enhance accuracy, minimize diagnostic time, and empower scalability. This paper employs a Convolutional Neural Network for automating malaria detection and classification using a dataset from the National Institute of Health (NIH) that is available publicly. The proposed model achieves an accuracy of 97.5%, and excellent results are performed regarding sensitivity and specificity when compared with machine learning algorithms such as Support Vector Machine (SVM) and Decision Tree. Furthermore, the results are validated using cross-validation techniques and compared with the existing methods. Our proposed CNN model can be deployed and potentially helps professionals with real-time malaria diagnosis and classification.
A Comprehensive Review for different perspectives in Ad-Hoc/ Cellular VANET Networks: Taxonomy, Challenges, Routing, Future Directions
Authors: Sadiq Alrubaye Jaafar , Abdkhaleq Mohamed H Ghaleb
Published: December 2024

The exploration of Vehicular Ad Hoc Networks (VANETs) has garnered attention from scholars and businesses alike because of their changing structure and expected traffic flow patterns. VANETs offer an avenue to boost road safety by offering drivers up-to-the-minute updates and predictions regarding road conditions. As a version of Mobile Ad Hoc Networks (MANETs) VANETs consist of units that can communicate wirelessly and share information.
This study explores elements of VANET (Vehicular Ad Hoc Networks) such, as structures and functions of networks connection points and the issues and methods used for guiding traffic efficiently to create a secure and dependable communication network system. Key indicators of performance like how many packets delivered (Packet Delivery Ratio. PDR) packet losses experienced during transmission processes are carefully analyzed to gauge the overall reliability of the system. Additionally, the research includes a comparison among routing strategies employed in VANET environments such as those based on network topology information or geographical location details, versus approaches centered around organized clusters of vehicles. Highlighting how these differ from methodologies typically seen in traditional cellular networks. This paper provides insights into how different routing protocols work in networking paradigms by examining different perspectives.
1999 Doğu Marmara Depremleri Sonrası Adapazarı Kent Dokusu: Karaman ve Beşköprü Mahalleleri
Authors: Sakar Seda , Zorlu Fikret , Taga Hidayet
Published: December 2024

Depremler başta olmak üzere herhangi bir afet anında meydana gelen kayıplar, kentsel dokunun tasarımı ile yakından ilişkilidir. Bu çalışma, 17 Ağustos ve 12 Kasım 1999 Doğu Marmara Depremleri sonrası yeni bir kent üst biçiminin ortaya çıktığı Adapazarı’nda; farklı düzeylerde gerçekleştirilen morfolojik analizleri, kentsel dokuyu meydana getiren fiziksel ölçütler bağlamında ele almaktadır. Kentsel alan ve mahalle düzeyinde gerçekleştirilen mekânsal analizler, tasarım özellikleri açısından deprem risklerini azaltmayı ve güvenli kentsel alanlar oluşturmayı hedefleyen planlı kent dokusunun önemini ortaya koymuştur. Analizler, planlı şekilde tasarlanıp uygulanan kent dokusunun; herhangi bir plan dâhilinde olmadan, mülkiyet sahiplerinin bireysel yönelimleriyle şekillenen düzensiz kent dokusuna kıyasla daha az risk barındırdığı tespit edilmiştir. Elde edilen bulgular, afetlere karşı güvenli kentsel çevrelerin oluşturulması için kapsamlı ve bütüncül planlama stratejilerine duyulan ihtiyacı vurgulamaktadır. Kapsamlı ve bütüncül stratejilerin varlığı, mevcut ve gelecekteki planlama yaklaşımları bağlamında önemlidir. Çalışma, kentsel morfolojinin, depremler karşında güvenli ve riski azaltmaya yönelik tasarım stratejilerinin geliştirilmesi üzerindeki etkisini ortaya koyarak, kentsel planlama ve tasarım literatürüne katkı sağlamaktadır.
Exploring Theoretical and Practical Shifts in Post-Venice Charter Conservation Perspective Through Reuse of Istanbul’s Industrial Heritage
Authors: Okyay Bayazit Gülce Güleycan , Kıraç Adile Binnur
Published: December 2024

The perpetually changing discipline of conservation creates its own field of action within the bounds of certain theoretical anchor points. One of the most prevailing expressions of this quest for a universal common ground that reflects the spirit of its time, is undoubtedly the Venice Charter, which is celebrating its 60th anniversary this year. The passing of time has revealed its stabilizing and enduring influence, while also prompting numerous discussions about its adequacy, timeliness, and validity, as well as the expanding potentials that the change being encountered may present. This study, therefore, aims to analyze the theoretical and practical shifts in post-Venice Charter conservation perspective through reuse of Istanbul’s industrial heritage. Focusing on a rather theoretically post-Venetian concept, and conjunctly, the prominent industrial complexes of the city, the study is carried out in two stages. The first stage exhibits the evolving perspective by meticulously examining the constituent dimensions of conservation theory in doctrinal documents. Subsequently, the on-the-field demeanour of the post-Venice Charter perspective is discussed through recent practices. By this means, the contemporary whereabouts of both theory and practice is explored comparatively to capture a greater context while also framing relatively more current concepts and approaches to conservation.
“A Home Away from Home”: The Case of the Yurt Homeland Association in Gebze
Authors: Yılmaz Hasan Ali
Published: December 2024

This article addresses the question of how hometown associations (HTAs, hereafter) transform into meaningful spaces, or homes, for internal migrant groups in Turkey and how they are perceived within this context. While previous research has primarily focused on the functions, transnational and translocal interactions, and contributions of HTAs to the migrants’ origin, spatial factors have often been overlooked. Utilising ethnographic research conducted from 2013 to 2018 and a review of existing literature on the topic of 'home' studies, this study examines how migrants create a sense of 'home' in HTAs, with a particular focus on the role of face-to-face interactions, objects, and practices. The research findings demonstrate that the transformation of HTAs into a 'home' is achieved through the actions of the association leaders and the utilisation of home-making practices and objects. These processes and interactions are crucial for fostering a sense of familiarity and comfort among migrants. Furthermore, the article underscores that migrants seek this sense of belonging, which significantly influences their identities. Ultimately, the spatial analysis of fellow townsmen associations demonstrates that the associations are not merely a physical structure; they are also an emotional labour, the implementation of which, objects, and interactions play a crucial role.
Urban Disaster Governance and Experiences of Earthquake Beyond the Disaster Region
Authors: Aydın Yahya
Published: December 2024

When a disaster occurs, attention is immediately focused on the affected region and continues throughout the recovery process. However, social groups beyond the region are often overlooked. After the Kahramanmaraş earthquakes in Turkey on 6 February 2023, hundreds of thousands of people were forced to relocate to different parts of the country. The capital, Ankara, quickly became the preferred destination for these forced migrations, turning it into a hub for those so displaced. This study examines the experiences of earthquake victims in a city located far from an earthquake zone. A convenience sample of 531 individuals affected by the disaster and residing in Ankara was selected. Respondents from various cities in the earthquake region, with a range of levels of education, age, and occupational backgrounds, participated in the survey. Ankara was chosen as a destination due to its safety in terms of earthquake, health, and education opportunities. The experiences of individuals following the earthquake vary significantly depending on whether they live at home, in a dormitory, or in a guest house. Those affected by the earthquake used different strategies to manage the crisis, as based on their social and economic status.
Unhealthy relationship with parents, so also with pornography? Examining links between pornography use, psychological outcomes, and parenting style.
Authors: Bosua Elize , Deighton Russell
Published: December 2024

Outcomes related to pornography use are subject to considerable debate. Some users experience problematic patterns of pornography use while others do not, and little is known about the susceptibility factors. To investigate whether parenting experience could be such a factor, a survey of 411 individuals’ experience of parenting style, pornography use and outcome variables (life satisfaction, post-use guilt and shame, and rape myth acceptance) was conducted. Results showed that permissive parenting style was associated with pornography use, and pornography use was significantly associated with lower life-satisfaction, greater rape-myth acceptance and decreased post-use guilt and shame. Further, the relationship between parenting variables and pornography use was not mediated by early exposure to pornography, however, the relationship between permissive parenting and pornography use was partially mediated by relationship status. Moderation analyses suggested that people who experienced a permissive parenting style were more susceptible to certain negative effects of pornography use (rape myth acceptance), while people with an authoritative parenting style, which is balanced and responsive, appeared to be less exposed to certain negative effects of pornography use (lower life satisfaction, guilt and shame). These findings are discussed in terms of possible mechanisms for the influence of parenting style.
Federated Learning in Medical Image Analysis: A Review of Shanghai's 2014-2024 Healthcare Innovations and Data Privacy Advances
Authors: Liu Ziyang , Chen Haoran , Du Yudai
Published: December 2024

Federated Learning (FL) has emerged as a significant approach to enhance data privacy, particularly in sensitive sectors like healthcare. By enabling collaborative machine learning across decentralized devices, FL ensures that data remains local, minimizing risks associated with centralized data storage. This paper provides an overview of data privacy advancements in FL, focusing on privacy-preserving techniques such as differential privacy and homomorphic encryption. While FL offers promising solutions for secure model training, it faces challenges like model inversion attacks, data poisoning, and regulatory concerns. Ethical issues regarding patient data sharing, governance, and ownership are also highlighted. Future research directions include optimizing quantization strategies within privacy-preserving frameworks and expanding compatibility with various neural network architectures. The integration of FL with technologies like blockchain is anticipated to further strengthen privacy standards and revolutionize healthcare applications. The ongoing development of federated learning frameworks will significantly impact the field of medical image analysis, providing enhanced privacy protections while improving model performance.
A Brief History of Machine Learning and Artificial Intelligence
Authors: Ghojogh Benyamin , Ghodsi Ali
Published: December 2024

Artificial Intelligence (AI) can be categorized into machine learning, soft computing (computational intelligence), and application of AI in various fields such as image processing, computer vision, signal processing, etc. Machine learning itself is categorized into statistical machine learning and deep learning. Soft computing contains fuzzy logic and metaheuristic optimization (intelligent search). The tasks of machine learning are classification, regression (prediction), clustering, reinforcement learning, feature engineering, and numerosity processing. Feature engineering is broken down into feature extraction (dimensionality reduction and manifold learning) and feature selection. Numerosity processing includes outlier detection (anomaly detection) and prototype selection/generation. This article first discusses the categories of AI and tasks of machine learning. Then, it reviews the history of AI, statistical machine learning, and deep learning.
Queerowy biodramat. Bajka dla dorosłych O mężnym Pietrku i sierotce Marysi
Authors: Sobiecka Anna
Published: December 2024

Celem artykułu jest próba analizy queerowego biodramatu Jolanty Janiczak O mężnym Pietrku i sierotce Marysi z 2019 roku. Strategia dramaturgiczna Janiczak zastosowana w jej “bajce dla dorosłych” opiera się na rewizji zastanych narracji biograficznych odnoszących się do wybranych faktów z życia Marii Konopnickiej i Marii Dulębianki, a wraz z nimi dominujących dyskursów społecznych i utrwalonych w nich regułach myślenia właściwych dla przełomu XIX i XX wieku. Przywoływane w dramacie fakty biograficzne poddawane są nieustającemu procesowi rewizji i stają się punktem wyjścia do krytycznego spojrzenia na losy obu bohaterek, a tym samym na utrwalone w literaturze i kulturze narracje o ich życiu. Autorski sposób prezentacji materiału faktograficznego podporządkowany zostaje strategii autotematycznej i metatekstowej, co w kontekście przemian kulturowych XXI wieku nadaje utworowi dodatkowych znaczeń, czyniąc z niego przykład queerowej metabiografii, zbudowanej na pograniczu przywoływanej przeszłości i anektowanej teraźniejszości.
We Belong Here: Queer Rurality and the (Eco)Poetics of New Nature Writing (Mike Parker, Luke Turner, Amanda Thomson)
Authors: Kusek Robert
Published: December 2024

This paper studies a body of hybrid non-fiction works that lie at the intersection of queer and nature writing and which articulate a new conceptualisation the queer subject’s relationship with rurality. Those pioneering narratives – which for the purpose of the present research have been labelled “queer new nature writing” – do not offer a simple reversal of the traditional mode of thinking about the agonistic character of the queer-rural dyad. Instead, having recognised the very potential and possibility of the queer life beyond the city, they remain deeply aware of the need to imagine new ways to think and write about their experience of queer belonging in the rural space. The major aim of the paper is thus to identify the signposts of queer new nature writing and argue in favour of acknowledging the micro-genre’s unique (eco)poetics: one that is distinguished by such markers as the exploration of queer rural heritage, counter-pastoralism, or the presence of the auto(eco)theoretical impulse.
Analisis Willingness To Pay Petani Terhadap Asuransi Usaha Tani Padi (AUTP) Di Kabupaten Blitar
Authors: Anisah Dhuhro , Yuliati Nuriah , Roidah Ida Syamsu
Published: December 2024

Sektor pertanian merupakan salah satu sektor yang mempunyai peranan penting dalam perekonomian nasional. Namun, petani sebagai pelaku usahatani sering menghadapi masalah produksi seperti kegagalan panen akibat perubahan iklim, serangan OPT, dll yang mengakibatkan menurunnya produksi dan pendapatan petani. Asuransi Usaha Tani Padi (AUTP) jenis bantuan pemerintah yang dirancang untuk melindungi petani dari risiko gagal panen. Penelitian ini memiliki tujuan untuk menganalisis persepsi dan nilai petani mengenai willingness to pay program AUTP serta faktor-faktor yang mempengaruhinya. Penelitian ini menggunakan analisis data deskriptif, skala likert, contingent valuation method (CVM), dan regresi linear berganda. Hasil penelitian menunjukan bahwasanya 1) Petani peserta program AUTP mempunyai persepsi positif dengan rata-rata todal skor 4,06. 2) Untuk program AUTP, rata-rata nilai WTP petani responden sebesar Rp.40.264/Ha/MT dan memiliki faktor variabel pendapatan dan jumlah tanggungan yang memiliki pengaruh signifikan serta variabel umur, status lahan, luas lahan, pendidikan, dan pekerjaan sampingan yang tidak memiliki pengaruh signifikan. Hasil ini memiliki kesimpulan bahwa petani responden mempunyai persepsi positif terhadap program AUTP sehingga membuka peluang untuk keberlanjutan program, namun meskipun petani mampu untuk membayar sebesar Rp.40.264/Ha/MT petani berharap bahwa pemerintah tetap memberikan subsidi premi sebagai upaya membantu meminimalisir resiko kegagalan panen yang mungkin diterima petani.
Analisis Faktor-Faktor yang Memengaruhi Nilai Tukar Petani Kedelai di Desa Nglebur, Kecamatan Kedungpring, Kabupaten Lamongan
Authors: Tiara Irma , Mubarokah  , Itasa Dita
Published: December 2024

Kesejahteraan petani dapat diketahui melalui besarnya perolehan Nilai Tukar Petani. Penelitian ini dilakukan dengan tujuan untuk menganalisis rata-rata Nilai Tukar Petani Kedelai beserta faktor-faktor yang mempengaruhinya di Desa Nglebur Kecamatan Kedungpring Kabupaten Lamongan. Lokasi Penelitian dipilih secara purposif dan data penelitian yang digunakan merupakan datasekunder dan data primer dari 76 responden petani. Analisis data yang digunakan yaitu Analisis Nilai Tukar Petani dan Analisis Regresi Linier Berganda. Pada Analisis tersebut menunjukkan bahwa Rata-rata nilai tukar petani kedelai di Desa Nglebur sebesar 118% artinya petani kedelai cukup sejahtera. Berdasarkan Uji F semua variabel berpengaruh signifikan terhadap Nilai Tukar Petani. Untuk hasil analisis Uji T menunjukkan bahwa faktor-faktor yang berpengaruh signifikan ternadap Nilai Tukar Petani adalah Luas Lahan, Biaya Produksi, Harga Jual, Jumlah Produksi, Pengeluaran Pangan dan Pengeluaran Non Pangan. Sedangkan Usia petani, Pendidikan petani dan Jumlah tanggungan keluarga tidak berpengaruh signifikan terhadap Nilai Tukar Petani Kedelai di Desa Nglebur.
Analisis Faktor Produksi Cabai Merah (Capsicum Annum L.) Di Kecamatan Beringin Sebagai Sentra Produksi Di Kabupaten Deli Serdang
Authors: Ramadhona Yulviane , Siregar Akbar , Effendi Ihsan
Published: December 2024

The demand for red chillies from both North Sumatra and outside North Sumatra is high, but farmers in Deli Serdang Regency the main producing area for red chillies have not been able to meet it. This study aims to analyze production factors of red chili production in Beringin District as a production centre in Deli Serdang Regency. The population of this study was the Juli Farmer Group in Beringin District, Deli Serdang Regency. The selection of this sample used simple random sampling so the sample obtained was 83 respondents from the Juli Farmer Group. The analysis tool used was multiple linear regression with the Cobb-Douglas model. The results of the study showed that production factors in the form of labor, land area, and capital had a significant effect on red chili production, while technology costs did not affect red chili production in Beringin District, Deli Serdang Regency. So it is hoped that with the addition of land area and capital and labor will increase red chili production and can meet market demand.
IN VIVO EVALUATION OF COMBRETUM INDICUM FLOWER METHANOLIC EXTRACT AS OINTMENT FOR BURN WOUND ON MALE MICE
Authors: Haroh Istik , Aryani Retno , Rosadi Imam , Nugroho Rudy Agung
Published: December 2024

Burns that are not treated properly can be dangerous, even can lead to death. Combretum indicum is reported to have anti-inflammatory, antibacterial, and high antioxidant activities, making it effective in healing dermal wounds. This study aimed to evaluate the wound healing effect of C. indicum flower methanolic extract on burn wound model in male mice. A total of 36 adult male mice were randomly assigned to 6 groups namely Negative control (I) without treatment; Positive Control I (II) with Burnazin treatment; Positive control II (III) with Vaseline treatment; Treatment group I (IV) with 25% concentration of C. indicum flower methanolic extract ointment; Treatment group II (V) with 50% concentration of C. indicum flower methanolic extract ointment; Treatment group III (VI) with 75% concentration of C. indicum flower methanolic extract ointment. Mice were treated daily for 20 days, and wound areas were observed every 2 days. Hydroxyproline level and total DNA content were tested on day-11. Skin tissue was analysed histologically. The results indicate that C. indicum flower extract accelerate wound healing process and repair the damaged skin tissue by accelerate the Proliferative phase.
TOXICITY OF ETHANOL EXTRACT OF PELAWAN LEAVES (TRISTANIOPSIS OBOVATA Benn.) ON THE HEMATOLOGICAL PROFILE OF WHITE RATS (RATTUS NORVEGICUS L.)
Authors: Yusfiati Yusfiati , Sari Marwan Avilia Dayang , Husadha Azura
Published: December 2024

Tristaniopsis obovata  Benn. is one of the herbal plants that contains phenolics flavonoids, saponins, tannins and steroids/triterpenoids. The secondary metabolites are known to have antioxidant activity and toxicity that can affect hematological profiles. This study aims to determine the toxicity effects of ethanol extract of T. obovata Benn. leaves on LD50 value, erythrocyte morphology, and hematological profile in white rats. The study used a Complete Randomized Design (CRD) with 4 treatments and 4 repeats. The treatment consisted of P0 (control), P1 (dose of 300 mg/kg body weight) (P1), P2 (dose of 2000 mg/kg body weight), and P3 (dose of 5000 mg/kg body weight). LD50 calculation using AOT 425 StatPgm software and hematological profile analysis using ANOVA. The results showed LD50 value of T. obovata Benn. leaf extract. was 1.750 mg/kg BW as mild toxic. The morphology of P2 erythrocytes shows abnormal form anisocytosis and P3 form Burr cells and macrocytosis. The administration of extract in all treatments  was not significant from the number of erythrocytes, leukocytes and hemoglobin comcentration of white rats.
Diplomasi Publik Arab Saudi Dalam Mencapai Visi 2030: Studi Kasus Pengembangan Liga Sepak Bola Profesional Saudi
Authors: Alfarizi Surya Maldini , Triantama Febry
Published: December 2024

This research discusses Saudi Arabia's public diplomacy efforts through the development of its professional football league which aims to achieve the 2030 vision. As one of the most popular and historic sports in the world, football has become an important instrument in a country's foreign policy, this is because Football has a big influence in influencing the public and establishing international relations. This research began by collecting and carefully examining all aspects of the public diplomacy efforts carried out by the Saudi Arabian government in its aim of achieving Vision 2030, which it launched in 2016. Based on the concept of Public Diplomacy and the theory of National Interest, this research focuses on The Saudi Arabian government's initiative in carrying out its public diplomacy activities through the development of its professional football league. The research also further analyzes Saudi Arabia's national interests that underlie its public diplomacy efforts. In this case, economic interests and national image interests are significant motivations that drive Saudi Arabia's ambitions in its public diplomacy efforts through the massive development of its professional football league. All the public diplomacy efforts have been placed under the interests of Saudi Arabia to make its professional football league a hope in achieving its 2030 vision.
Design and Development of an Android-Based Merchandise Management Application for K-pop Consignment Services
Authors: Cahyani Nilam Putri , Sutarman Sutarman
Published: December 2024

The rapid development of technology has increased various societal needs, especially in the e-commerce sector, including the delivery service of K-pop merchandise. The global popularity of K-pop has led to high demand for related merchandise such as albums, lightsticks, and exclusive clothing and accessories, often difficult to source internationally. This demand creates challenges for businesses in managing product data, inventory, and transactions effectively. Zena.id, as a business providing K-pop merchandise delivery services, faces specific issues with ensuring accurate transaction recording and real-time inventory monitoring. An efficient system is needed to reduce human error, prevent inventory discrepancies, and meet customer expectations for product availability. This research aims to develop an Android-based application to automate transaction recording and inventory monitoring at Zena.id. The application is designed to improve operational efficiency through an integrated system for accurate stock monitoring and transaction processing. Developed using the Kotlin programming language and an Agile approach, this method allows for flexible, iterative improvements. Testing results showed a 83.33% accuracy rate in transaction processing and inventory updates, significantly simplifying management tasks and reducing potential errors. Additionally, the user-friendly interface enhances satisfaction for both business managers and customers. This application serves as an optimal solution to address the unique challenges faced by K-pop merchandise delivery services in the digital era.
Development of Paramadina Roomhub Application As Room Booking System Using Waterfall Method
Authors: Maulana Reza Arif , Fatih Muhamad Adillah , Suto Lintang Arbi , Darwis Muhammad
Published: December 2024

The manual room booking process at Paramadina University faces several challenges, including inefficiencies, human errors, and communication breakdowns between applicants and facility managers. These issues often result in room booking conflicts and delays, hindering effective facility usage. The need for a more streamlined, user-friendly solution led to the development of the Roomhub Paramadina application, a web-based system designed to facilitate room bookings within the university. The objective of this research is to design and implement a digital room booking system that simplifies the current manual process. The application was developed using the Software Development Life Cycle (SDLC) with the Waterfall framework. This approach ensures structured and systematic development, enabling the team to follow sequential stages from requirements gathering to testing. The Roomhub application allows users to view available rooms, submit booking requests, and receive confirmations directly via an online platform. The system integrates with existing university infrastructure and ensures real-time room availability, reducing errors such as double bookings. Black-box testing was employed to verify the application’s functionality, and the results confirmed that the system meets user needs while significantly improving booking efficiency. By automating room bookings and enhancing communication between the parties involved, this research offers a practical solution that improves operational efficiency, reduces paperwork, and minimizes scheduling conflicts, thereby benefiting the entire academic community at Paramadina University.
Vehicular Ad-Hoc Networks for Intelligent Transportation System: A Brief Review of Protocols, Challenges, and Future Research
Authors: Bintoro Ketut Bayu Yogha
Published: December 2024

Vehicular Ad Hoc Networks (VANET) play an essential role in the advancement of intelligent transportation systems, facilitating real-time communication between vehicles (V2V), infrastructure (V2I), and surrounding environments (V2X). This systematic review analyzes a range of VANET routing protocols, highlighting the strengths and weaknesses of topology-based, position-based, cluster-based, and hybrid methods. Additionally, this review explores core challenges in VANET, including high mobility, data security, Quality of Service (QoS) requirements, and connectivity issues in dynamic and high-density traffic environments. The paper also provides insights into simulation tools and performance metrics employed in VANET research alongside practical applications in modern transportation systems, such as autonomous driving, traffic management, and safety-related communication. Furthermore, this review emphasizes the need for ongoing research to address the identified challenges and optimize VANET performance. Integrating emerging technologies, including 5G, artificial intelligence (AI), and edge computing, offers promising avenues for enhancing system efficiency and sustainability. This review establishes a comprehensive foundation for further advancements in VANET by highlighting key findings and research gaps. Ultimately, the effective implementation of VANET has the potential to significantly improve transportation safety, efficiency, and sustainability, contributing to the realization of smart city initiatives and innovative mobility solutions. This work aims to guide future research directions, ensuring that VANET continues to evolve in alignment with the demands of modern transportation systems and the broader context of intelligent mobility.
Molecular Diagnostics for Infectious Diseases in Low or MiddleIncome Countries
Authors: Prof. Dr. Andreas Nitsche
Published: December 2024

Infectious diseases remain a leading cause of morbidity and mortality in Low and MiddleIncome Countries (LMICs). Indisputably, molecular diagnostics is the key to a rapid and reliable identification of an infectious agent in clinical specimens. Unlike traditional techniques, such as microscopy and cell culture, molecular diagnostics can detect extremely low levels of pathogens within a short time and can provide additional information about the pathogen by looking at the genome. The term molecular diagnostics encompasses various laboratory techniques that directly target the DNA or RNA genome of pathogen, the proteome of a pathogen, or in an indirect manner, the immune reaction of the infected system to a specific pathogen. In a particular setting, molecular diagnostics can replace, support or confirm a clinical diagnosis and is specifically helpful for differential diagnosis in infectious diseases, that cross-present a high similarity in clinical symptoms
Siamese Hybrid Network Approach for Sentence Similarity
Authors: D.A.A. Deepal  , A.M.R.R. Bandara  , P.R.S. De Silva
Published: December 2024

This paper presents a novel Siamese Hybrid Network approach, namely Siamese Bidirectional Long Short Memory with Convolutional Neural Network (SiBiLConv), for evaluating the similarity in natural language. The model integrates a Siamese neural network architecture with similarity metrics, including Manhattan Distance and Cosine Similarity, to improve the accuracy of semantic relationships measurement between sentences. Evaluations were performed on Sinhala, a complex and under-resourced language spoken in Sri Lanka, which poses unique challenges due to its morphological richness and syntactic variability. The SiBiLConv model achieved an accuracy of 89.80%, an F1 score of 0.9041, and a mean squared error (MSE) of 0.0281 with the Cosine Distance metric outperforming baseline models such as MaLSTM, which achieved an accuracy of 78.99% and an F1 score of 0.7797. While existing methods for sentence similarity primarily focus on resource-rich languages, this work addresses the pressing need for tailored approaches in low-resource language contexts, where pre-trained models and annotated datasets are often limited. The novelty lies in SiBiLConv's hybrid architecture and metric integration, specifically designed to overcome the syntactic and semantic complexities of Sinhala. This research not only bridges a critical gap in the application of sentence similarity models for low-resource languages but also establishes a framework adaptable to other morphologically rich languages, advancing the broader scope of natural language processing.
Keywords: Siamese Hybrid Network, Sentences similarity, Sinhala sentence similarity, Morphologically Rich Language Processing
GAMIFICATION AS A EDUCATIONAL TECHNOLOGY FOR PROFESSIONAL TRAINING
Authors: Pavlova Nataliia , Shrol Tetiana , Poliukhovych Nataliia
Published: December 2024

The article considers gamification as a technology that involves the use of game elements in the educational process to enhance the motivational, value and practice-oriented of teaching students. The motivational, communicative, developmental, diagnostic, emotional, and correctional functions of gamification are highlighted, based on the peculiarities of professional training of specialists in higher education institutions. The didactic conditions under which the educational process acquires the characteristics of a learning and gaming environment are determined. The relevance of such training is due to the fact that game elements, diversifying the process of acquiring knowledge, encourage students to be motivated to carry out educational and cognitive activities. The structure and content of the discipline «Gamification in Education» are described and a corresponding distance course on the Moodle platform is developed in such a way that gamification is both an object of study and a means of learning. Attention was paid to the organisation of practical and laboratory classes, where students acquired knowledge and skills in working with Kahoot, Canva, LearningApps, Wordwall, Scratch, Minecraft and other software environments. A scheme for organising and implementing the educational process using the Moodle platform was developed. The effectiveness of the use of gamification in the process of professional training of specialists has been experimentally confirmed through the approbation of a distance course. A direct correlation between students' motivation to learn using game technologies and the results of their study and readiness to apply them in further education and professional activities has been established. To this end, the results of a pedagogical experiment involving 124 students of Rivne State University of the Humanities are presented.