bluuebunny/crossref_metadata_2025 huggingface dataset:
Pricing and risk adjusted measures
Authors:   University of Essex and University Roma III,   University of Essex and University Roma III, Fiordelisi Franco , Meglio Corrado , Palego Carlo ,   Banca di Asti, Richetto Annalissa ,   IntesaSanPaolo, Danko Artem ,   Unicredit, Vallino Maurizio , Porretta Pasqualina ,   Università di Roma, Bocchi Lorenzo ,   Prometeia, Toffano Carlo ,   Prometeia, Favretti Andrea ,   Prometeia
Published: April 2021

The issue of risk-based pricing of credit loans has become crucial for banking companies, in a context characterized by severe restriction of profitability margins also in relation to a level of market interest rates which in the Euro area is at its lowest. historical, now firmly in the negative area. The same European Authorities urge the adoption of adequate and consistent adjusted pricing frameworks with respect to the business model, risk profile and overall risk governance of the bank. The methodological and organizational process for determining the risk-adjusted pricing is further complicated by the ongoing Covid19 pandemic which, through the highly asymmetrical impacts on customer segments and industrial sectors, makes the forward-looking and macroeconomic assessment of the sectors risk even more relevant.
Low dose whole Lung Therapy for patients with SARS-CoV-2
disease (COVID-19) Pneumonitis
Authors: Pankov Pavel D. , Salpagarov Magomet KH. , Yakovleva Natalia N. , Andronov Alexey V. , Baranov Grigory А. , Fursov Sergey A.
Published: April 2021

In this article provides an overview of publications by foreign authors of the novel coronavirus (SARS-CoV-2) and introduce a
modified treatment method for COVID-19-associated pneumonia. X-ray therapy was used to treat pneumonia during the first half
of the 20th century. Fifteen studies report that approximately 700 cases of bacterial (lobar and bronchopneumonia), sulfanilamide
non-responsive, interstitial, and atypical pneumonia were effectively treated by low doses of X-rays, leading to disease resolution, based on clinical symptoms, objective disease biomarkers, and mortality incidence. The capacity of the X-ray treatment to reduce mortality was similar to serum therapy and sulfonamide treatment during the same time period. The mechanism by which the X-ray treatment acts upon pneumonia involves the induction of an anti-inflammatory phenotype that leads to a rapid reversal of clinical symptoms. The capacity of low doses of X-rays to suppress inflammatory responses is a significant new concept for treatment COVID-19 pneumonitis. Low dose whole lung irradiation may be a potential solution in the present time. International research organization and the International Geriatric Radiotherapy Group (http://www.igrg.org) proposed a simple and practical protocol for Low dose whole lung irradiation to allow participation of all countries in the world regardless of their resources and made available to the whole world community for treatment COVID-19 pneumonitis.
ANALISIS HUBUNGAN TINGKAT PEMAHAMAN MATERI PERKULIAHAN PENGANTAR ILMU LINGKUNGAN DENGAN MENGGUNAKAN GOOGLE CLASSROOM TERHADAP HASIL BELAJAR MAHASISWA
Authors: Van Harling Vina N
Published: April 2021

Google classroom merupakan layanan yang dikembangkan oleh google dalam hal ini adalah Google for Education yang memiliki tujuan menyederhanakan tugas para pengajar. Penelitian ini dilakukan dengan tujuan untuk menganalisis hubungan tingkat pemahaman materi perkuliahan pengantar ilmu lingkungan dengan menggunakan google classroom terhadap hasil belajar mahasiswa. Penelitian ini merupakan penelitian korelasional, data penelitian dikumpulkan dengan menggunakan metode pengumpulan kuesioner dan metode dokumentasi. Penelitian dilakukan di Politeknik Saint Paul Sorong, program studi Teknik Elektro, sampel yang digunakan 9 orang dari total populasi. Hasil pengujian diperoleh r hitung dari hasil pengujian hubungan antara tingkat pemahaman materi perkuliahan pengantar ilmu lingkungan dengan menggunakan Google Classroom terhadap hasil belajar mahasiswa sebesar 0,158 yang bila dibandingkan hasil pengujian dengan nilai r table, maka nilai r hitung < r table (0,158 < 0,666). Sementara perbandingan signifikansi diperoleh nilai signifikansi > 0,05 (0,686 > 0,05) yang berarti bahwa tidak terdapat hubungan antara kedua variable yang diujikan
Belangrijk gewichtsverlies bij een patiënt met een hardnekkige huideruptie
Authors: VANBELLEGHEM E. , WERBROUCK J. , VERSTRAETE S. , LIBBRECHT L. , D'HEYGERE F.
Published: April 2021

Persistent skin eruption in a 52-year-old man losing weight

This case report describes a 52-year-old male patient with important weight loss, fatigue, diarrhea and a skin eruption since 1 year. An olmesartan-induced enteropathy and skin vasculitis were diagnosed. There was a total resolution of the symptoms after the interruption of olmesartan. Although sprue-like enteropathy and cutaneous vasculitis are very rare, clinicians should be aware of those potential adverse events, even years after the initiation of an angiotensin II receptor blocker.
Multimodality imaging in arrhythmogenic cardiomyopathy
Authors: Tapoi Laura , Clement Alexandra , Radu Rodica , Sascau Radu
Published: April 2021

Arrhythmogenic cardiomyopathy, as it has been recently redefined, is characterized by progressive myocyte loss with fibrosis and fat infiltration of the myocardium, which finally leads to a broad clinical spectrum ranging from heart failure symptoms to sudden cardiac death. The diagnosis of arrhythmogenic cardiomyopathy is challenging particularly because of its heterogeneity in presentation, which varies from focal right ventricular involvement to biventricular or prominent left ventricular phenotype. In the past decades, the development of new electrocardiographic and imaging diagnostic criteria for arrhythmogenic cardiomyopathy constituted an important area of research and resulted in the elaboration of the Padua criteria. However, even with the widespread availability of modern imaging techniques, there is still a lack of awareness in the health care community and this pathology persist in being under- or misdiagnosed. Given the limited indication of endomyocardial biopsy for the diagnosis of arrhythmogenic cardiomyopathy, one can conclude that the progress that has been made in the last few years in the multimodality imaging field is of utmost importance for the early detection and proper treatment of patients with arrhythmogenic cardiomyopathy, providing valuable prognostic information.
Multimodality imaging can shift the clinical approach and prognosis of a patient: from heart failure and angina to cardiac amyloidosis
Authors: Chitroceanu Alexandra Maria , Nicula Alina Ioana , Rimbas Roxana Cristina , Andreescu Mihaela , Popp Cristina , Stoicescu Claudiu , Vinereanu Dragos
Published: April 2021

AL (light chain) amyloidosis is a life threatening disease. Untreated patients with involvement of the heart, a condition known as cardiac amyloidosis (CA), tend to have the most rapid disease progression and worst prognosis. Therefore, it is essential to early recognize the signs of symptoms of CA, and to identify the affected individuals with readily available non-invasive tests, as timely therapy can prolong life. Different imaging tests are used to diagnose and stratify the risk of the disease noninvasively, and to follow-up of the disease course and response to therapy. In this light, we present a case of a woman with cardiovascular risk factors, initially admitted for typical angina and decompensated heart failure (HF), who was later diagnosed with AL amyloidosis with cardiac involvement, by using multimodality imaging assessment in a step-by-step fashion. This changed completely the prognosis of the patient. Timely chemotherapy and stem cell transplantation led to an improvement in clinical status, biomarkers, and in a regression of amyloid myocardial infiltration showed by imaging.
Mitral annulus dynamics in myxomatous mitral valve disease
Authors: Gurzun Maria-Magdalena , Rosca Monica , Calin Andreea , Beladan Carmen , Serban Marinela , Enache Roxana , Jurcut Ruxandra , Ginghina Carmen , Popescu Bogdan A.
Published: April 2021

Myxomatous mitral valve disease (MVD) is a common disorder in which the entire mitral valve apparatus seems to be involved. Mitral valve repair is nowadays the method of choice for the correction of mitral regurgitation but the optimal shape and flexibility of the annuloplasty ring remain controversial. Considering that myxomatous MVD covers a wide spectrum from limited fibro-elastic deficiency to extensive Barlow disease, we presume that the mitral annulus morphological and functional changes are likely different in different types of myxomatous MVD. We analyze the 3-dimensional geometry and the dynamics of the mitral annulus in 110 patients with significant mitral regurgitation due to different types of myxomatous mitral valve disease and 40 normal subjects using 3D transesophageal echocardiography. The mitral annulus differs in patients with limited MVD, extensive MVD and in normal controls in terms of size, shape, and dynamics Patients with limited MVD have larger, flatter, dysfunctional and more mobile mitral annulus compared to normal, while patients with extensive MVD have even larger, flatter and more dysfunctional mitral annulus, with reduced mobility. The non-planar dynamics has different patterns during systole, according to the extension of MV disease. Our data may be important for the appropriate choose of annuloplasty mitral annulus in mitral valve repair, the current trend being to choose the ring according to the underlying pathology.
Acute symptomatic seizures and ventricular fibrillation - a multimodality approach to a rare complication of myocardial infarction. Case report
Authors: Stefan Miruna Florina , Magda Stefania Lucia
Published: April 2021

Background

6–8% of patients with acute myocardial infarction still develop ventricular arrhythmias (VA), although their incidence has lowered due to prompt antiischemic treatment. VA might determine sometimes acute symptomatic seizures.

Case report

A 44-year old male was admitted to our unit with acute inferior myocardial infarction. Emergency coronary angiography was performed and revealed acute occlusion of the right coronary artery. The procedure was complicated by coronary dissection, which was sealed, with good final results. After admission in the acute coronary unit, the patient developed ventricular fibrillation. He was successfully resuscitated, but developed ongoing tonic-clonic seizures, terminated after intravenous administration of several anticonvulsivant drugs. We investigated the patient for epilepsy and for other pathologies that could explain both the VA and the seizures. All investigations were within normal range.

Conclusion

Differential diagnosis between hypoxic and epileptic seizures is difficult and important, because it further influences patient management. Cardiac arrhythmias are a rare precipitating factor for acute symptomatic seizures, due to hypotension-induced cerebral hypoxemia. Our case illustrates the value of a multimodal approach of rare complication of a myocardial infarction.
Character Development and Youth Leadership Mentoring
Authors: Arshad Mohd Mursyid , Ismail Ismi Arif , Ahmad Fesol Siti Feirusz , Ismail Azman
Published: April 2021

One approach that promotes Positive Youth Development (PYD) among youth is being involved in leadership activities. Focusing on the mentoring process in a leadership development program serves as the foundation for cultivating these positive aspects for the young generation. The purpose of this study is to explore the character development process in promoting developmental assets through youth leadership mentoring. The study was conducted using qualitative research informed by the case study paradigm that involved 13 informants through in-depth interview, participant observation and document analysis as data collections. Empirical findings from the study show that mentoring process such as the display of prudent characteristics, integrity development and preferred leadership style among youth leaders lead to character development. In conclusion, the data indicated that mentoring clearly had the potential to constitute the process of character building among youth. This youth leadership mentoring process contributes to the development of their capabilities in leadership and enhances the implementation of effective youth leadership mentoring processes.
Role of Career Exploration in Influencing Career Choice among Pre-University Student
Authors: Yusran Noor Ashira , Mohd Puad Mohd Hazwan , Omar Muhd Khaizer
Published: April 2021

In the age of innovation, digitalization, and globalization today, deciding to take a career path has been growing and challenging. The career path continues to increase its stature as a career choice, pursued by many in an evolving, unpredictable, and competitive marketplace. Students’ general career selection process is the first step to ensuring that human resources align with the labor market demands. This study aimed to determine the role of career exploration as a mediator in the relationship between social support and career self-efficacy on career choices among pre-university students. This research is a quantitative and correlational study conducted on students in the Agricultural Science of Foundation program at Universiti Putra Malaysia. By using simple random sampling, 249 students were selected based on Cohen’s calculation. The researchers used the Career Exploration Survey (CES), Multidimensional Scale of Perceived Social Support, Career Decision-Making Self-Efficacy Scale-Short (CDSE-SF), and career choice instrument surveys to measure the variables in this study. The results show that career exploration acts as a partial mediator in the relationship between social support and career self-efficacy on career choice. There is not only a significant relationship between the career exploration and the career choice, but also some direct relationship between the social support, career self-efficacy and career choice. This study provides a basis for reference to academicians and instructors designing the pre-university student curriculum in choosing a career. Teachers are also recommended to play an active role in initiating career exploration activities for students during their learning process.
Psychometric Properties of the Multicultural Counselling Competence Training Survey-Revised (MCCTS-R): Application for Counsellor Trainees in Malaysia
Authors: Harun Maizatul Mardiana , Wan Jaafar Wan Marzuki , Ismail Asmah , Mohd Noah Sidek
Published: April 2021

The purpose of this study is to examine the reliability and validity of the translated and adapted Multicultural Counselling Competence and Training Survey-Revised (MCCTS-R) for its use in measuring perceived multicultural counselling competence among counsellor trainees in Malaysia. This descriptive-correlational study was conducted on 208 counsellor trainees from local universities. They were chosen through cluster random sampling. The drawing procedure was done using a fishbowl method. At the time of data collection, the counsellor trainees were at the end of their counselling internship in various organisations around Klang Valley and East Malaysia during the study. Based on the factor analysis, the three-factor structure, which was the same as the original version, was confirmed with 20 items retained. For reliability, internal consistency and construct reliability were evaluated and confirmed. The finding showed that internal consistency was α = .952 and construct reliability was .882. In addition, MCCTS-R was found to have good construct validity based on the corrected item-total correlation value, which varied from r = .533 - .756. The convergent validity value obtained from the confirmatory factor analysis was .714. Overall, the factor structure, reliability, and validity of the adapted MCCTS-R were all confirmed in this study. The high reliability and good validity indicate that MCCTS-R can successfully be used by counsellor trainees across gender and ethnicity. The findings can be a starting point for multicultural counselling to gain greater focus from the counselling academia and professionals as it gives a mere reflection of counsellor trainees perceived multicultural counselling competence.
Impact of Scientific Calculators in Mathematics among Low- Achieving Students in a Secondary School in Kajang, Selangor
Authors: Radzuan Fatimah Salihah , Kamarudin Nurzatulshima , Md Khambari Mas Nida , Mohamad Arsad Nurazidawati
Published: April 2021

This study aims to investigate the effects of scientific calculators on mathematics achievement in support of problem-solving instructions. In this study, 49 low achieving mathematics students aged 14 years were selected from a secondary school in Kajang, Selangor, Malaysia. A pre-test post-test quasi-experimental design with two groups was employed in this action research study. The experimental group learned solid geometry and statistics topics, with the aid of a scientific calculator; while the control group did not use any technological aid to learn these topics. By controlling the pre-test score, the ANCOVA two-way test was applied to the post-test results. A positive significant difference was reported in favour of the experimental group. However, no significant interactions were noted between group and gender. The analysis results indicate that the use of a scientific calculator in the integrated teaching and learning of mathematics helped the students improved their mathematics achievements. These findings have important implications in the educational setting, particularly for educators to support and facilitate low-achieving students in mathematics.
Role of Principal in Promoting Teachers Unity: Evaluation in Malaysian Secondary Schools
Authors: Alias Bity Salwana , Zainuddin Zaida Nor , Ishak Mohd Radzi , Mansor Azlin Norhaini
Published: April 2021

The inability of teachers to accept cultural, linguistic, and religious differences caused by racial differences can have a negative impact on unity. The literature suggests that principals can play a role in addressing this issue. Thus, the purpose of this study is to determine the principal’s role in promoting teachers’ unity and to determine the relationship between the principal’s role and teachers’ unity. This study is a survey design and a quantitative method was used to collect data from 578 teachers in a population of 236,748 teachers in secondary school. The data collected was analyzed descriptively to produce mean value and standard deviation, therefore the level of principals’ role in promoting unity and the level of teachers’ unity can be interpreted. Inference analysis by Pearson correlation was done to determine r-value, therefore the hypotheses on the relationship between the two variables were tested. Overall, principals’ role attained a high level in promoting unity with a mean score of 3.85, whereas the teachers’ unity level was also at a high level with a mean score of 4.37. The result also shows that there was a positive relationship between the two variables but at a weak level with r = 0.20. This paper contributes to the body of knowledge that principals’ role in promoting unity has had an impact on the teachers’ unity level. This finding also shows that the Malaysian Education System Aspiration focusing on promoting unity is relevant and should be continuously implemented. Apart from having theories implication, the findings bear positive input for principals’ training, and also provide input for the teaching fraternity to be more respectful towards each other’s differences, thereby avoiding racism and discrimination amongst them.
KLARNET İCRACILARI İÇİN BEDENSEL VE RUHSAL GEVŞEME TEKNİKLERİ VE UYGULAMALARI
Authors: UYAR Orkun
Published: April 2021

Enstrüman çalan tüm bireylerin normal yaşantısından farklı olarak performans ve çalışmaları esnasında vücüdunda bir takım fiziksel hareketler gözlenmektedir. Diğer tüm müzisyenlerin yaşadıkları değişimlere ek olarak üflemeli çalgı çalan kişilerin vücudunda nefes kullanımı devreye girmekte ve sarfedilen efor daha da artmaktadır. Yaşanan bu fiziksel gelişmelerle birlikte, bir o kadar önemli olan konu da ruhsal değişimlerdir. Müzikte hissedilen duyguların aktarılma arzusuyla birlikte, performans sırasında hissedilen heyecan, kontrolü kaybetme veya başarısız olma korkusu, başarısız olunması halinde başkalarının sizin hakkınızda kötü düşüneceği endişesi gibi düşünceler çalıcının performansına olumsuz etki edebilmektedir. Bu olumsuz durumların tekrarlanabileceği düşüncesi çalıcı üzerinde strese yol açabilmektedir.

Stres, her insanın ve günlük yaşantısının ayrılmaz bir parçası olan, karşılaştığı zorlukların ve yaşam şartlarının kişiye etkisiyle oluşan ruhsal gerilim durumudur. Her türlü yaşam zorluğu, ihtiyaçlarını giderme çabası ve yaşamını devam ettirme konusunda karşısına çıkan tüm engeller, kişiyi baskı altına almakta ve gerilim hissetmesine yol açmaktadır. Stres düzeyi kontrol altına alınamadığı ve stresin devamlılığı engellenemediği takdirde, bireylerin vücudunda kasılmalar ve çeşitli rahatsızlıklara kadar uzanan sorunlarla karşılaşılabilmektedir. Enstrüman icrasında da ruhsal etkenlerin, bedensel durumları doğrudan etkilediği gözlemlenmekte ve bu konudaki rahatlamanın tüm performansa katkıda bulunduğu anlaşılmaktadır.

Bu araştırmada; konservatuvar öğrencilerinin ve klarnet çalıcılarının performanslarında, kayıpların en aza ineceği şekilde kaygı, stres yönetimi teknikleri ve uygulamaları konusunda tavsiyelere değinilmiştir. Bunun yanısıra klarnet icracılarının müziğine, ifadesine destek olacağı düşünülen nefes teknikleri ve uygulamaları hakkında da bilgiler verilmiştir. Bu çalışma, klarnetçilere ek olarak tüm üflemeli çalgı ailesi icracılarının yararlanabileceği stres yönetimi, performans hazırlığı ve doğru nefes alışverişi konuları hakkında bir kılavuz olmayı amaçlamıştır.
TÜRK MÛSİKİ TARİHİNDE MEVLEVİ MUSİKİSİNİN YERİ, ÖNEMİ VE ETKİ ALANLARI HAKKINDA GENEL BİR DEĞERLENDİRME
Authors: MACİT Mustafa
Published: April 2021

Büyük tasavvuf düşünürü olan Mevlâna’nın vefatından sonra oğlu Sultan Veled tarafından kurulan Mevlevi tarikatı insana saygı ve sevgiyi merkeze alarak sağlam temeller üzerine kurulmuştur. Mevlevi öğretilerini gelecek kuşaklara aktarmada musiki ve şiirin etkili bir şekilde kullanması Mevleviliği bir ekol haline getirmiştir. Mevlevi tekkelerinin musikiye verdiği destek ve hizmetler zaman içerisinde profesyonellik seviyesine ulaşarak, dönemin sanat eğitimi veren konservatuvarları görevini üstlenmiştir. Mevlevi musikisi formlarından en büyük form olan Ayin-i Şerif’in bestelenmesi ve bu denli yüksek nitelikli musiki birikimi, önemli bestekârların yetişmesi, Türk musikisi sazlarının sayısının artarak Mevlevi musikisinde yer bulması, çok büyük önem taşımaktadır. Bu bağlamda Mevlevi tekkelerinde icra edilen musikinin Türk musikisine katkılarının yadsınamaz bir olgu olduğu görülmektedir. Bu çalışmada, Mevlevilik ve Mevlevi musikisini oluşturan temel dinamikler çerçevesinde ele alınarak incelenmiştir. Türk musikisine katkı sağlamak amacıyla, Mevlevi musikisinin geçmişten günümüze kadar olan süreçte Türk musikisi üzerindeki etkilerini araştırarak Türk musikisine katkıları ortaya koyulmaya çalışılacaktır.
FRANCIS POULENC’İN FLÜT VE PİYANO SONATI HAKKINDA BİR İNCELEME
Authors: ÖNVER ZAFER Çisem
Published: April 2021

Çağdaş dönem müziği denilince akla gelen isimlerden biri olan Francis Poulenc, üflemeli çalgıların repertuvarlarına zenginlik kazandırmıştır. Sadece piyano eşlikli eserler değil, oda müziği alanında da çalışmalar yapan besteci, dönemin özelliklerini müziğine yansıtmıştır. Aynı zamanda kendine has melodik yapıları da eserlerinde kullanan besteci, klasik müzikte tanınan isimler arasında yerini almıştır. Bestecinin melodik üslubunu sergileyen en önemli örnekler arasında üç eser, Flüt ve Piyano için Sonat (1956-57), Klarnet ve Piyano için Sonat (1962) ve Oboe ve Piyano için Sonat (1962) sayılabilir. Tek bir nefesli çalgı ve piyano, her üflemeli çalgının tamamen yeteneklerini gösterdiği ve şiirsel bir metnin yokluğu göz önüne alındığında, saf melodik çizginin ifadesi için mükemmeldir. Ayrıca bu eserler altı yıl içinde yazılmış olup, bestecinin en olgun tarzını temsil etmektedirler. Bu bağlamda yazdığı flüt ve piyano sonatı birçok öğrenci ve sanatçının repertuvarında yer alan gözde eserlerin başında gelmektedir.
Remote Detection for the Presence of NH3, CO2, CH4, H2S, CO and Other Toxic Gases at Various Locations in a Sewer to Alert the User
Authors: Uthayakumar Dr. G. S. , Tomson F. Albinus Sagay , Ashwin R.
Published: April 2021

Sewer gasis a complex mixture of toxic and nontoxic gases produced and collected in sewage systems by the decomposition of organic household or industrial wastes, typical components of sewage. Sewer gases may include Hydrogen Sulphide, Ammonia, Methane, Sulfur Dioxide, Carbon Monoxide and Nitrogen oxides. This project aims to deliver a system that will be useful in detecting and alerting the user before getting exposed to the toxic gases accumulated inside the sewer. This project uses MQ-135 and MQ-4 sensors to detect various toxic gases such as NH3, CO2, CH4, H2S and CO. This project also has a water level detection sensor which is used to detect the level of water and to reveal any blockage present inside the sewer. These detected gases are measured using the unit “parts per million (ppm)”. It is then compared with the threshold values that have been fed earlier inside the controller. If the detected values are higher than the threshold value, then a warning is sent to the user along with the ppm values. If the detected values are lower than the threshold value, then only the ppm values are shown to the user without any warnings. This project stores the values recorded in a dedicated webpage. This is where the information from our system is displayed to the user.
Factors Influencing Fixed-Route Transit Decision-Making: Exploring Differences by Disability and Community Type
Authors: Maisel Jordana , Ranahan Molly , Choi Jimin
Published: April 2021

Transit agencies utilize the following complementary initiatives to encourage greater fixed-route transit usage by people with disabilities: (1) implement more rigorous paratransit eligibility determination practices and (2) address the factors that deter people with disabilities from using fixed-route transit. This research focuses on the latter and uses previously conducted survey data to determine the most important factors individuals with disabilities consider when deciding to use various transportation options, and how these factors vary by disability and community type. Findings indicate that individuals with mobility impairments consistently rated the built environment factors as more important to their transit mode decision-making than scheduling-related factors. Findings also highlighted the importance of addressing complex trips when assisting riders with intellectual and cognitive disabilities. The current study also revealed that people with disabilities experience barriers differently based on where they live, suggesting the need for context sensitive interventions to support fixed-route ridership. Transit agencies should utilize this information to employ more targeted interventions to encourage greater fixed-route transit usage for individuals with disabilities.
Zinc deficiency: A cause of opioid-induced physical dependence and addiction in post-operative total hip arthroplasty patients
Authors: Tantillo, DO Tyler J. , Jagtiani, DO Manoj R. , Silverman, MD Eric R. , Bitterman, DO Adam D. , Scuderi, MD Giles R.
Published: April 2021

Objectives: Recently, opioid abuse and related overdoses have increased warranting the need for research directed against the opioid epidemic. Previous studies identified that patients on opioid therapy may become zinc deficient and that zinc, in a murine model, may antagonistically affect the opioid receptor.13 Further understanding the relationship between opioid use and zinc deficiency may mitigate the opioid epidemic.Methods: A retrospective study was conducted to identify zinc (Zn2+) deficiencies among post-operative total hip arthroplasty (THA) patients. On post-operative day one, patients had routine blood tests, including Zn2+ plasma levels. Patients were considered Zn2+-deficient if their Zn2+ plasma was < 56 μg/dL (Reference: 56-134 μg/dL). Upon discharge from the hospital, the patients’ inpatient opioid medication consumption per day was determined by dividing total morphine milligram equivalents (MMEs) by length of stay. A Student's t-test was performed to compare the total MMEs for Zn2+-deficient patients versus Zn2+-normal patients. A univariate analysis followed by multiple linear regression was performed to identify demographic or surgical predictors of MMEs/day. Results: For Zn2+-deficient patients, the total MMEs/day was 33.62 ( ± 27.06), as compared to Zn2+-normal patients who consumed 16.22 ( ±16.01) MMEs/day (p = 0.031). The univariate analysis and multiple linear regression showed that patients’ Zn2+ status had a significant contribution toward predicting MMEs/day, with p = 0.022 and p = 0.04, respectively.Conclusion: The results of this study suggest that Zn2+ deficiency may potentiate opioid consumption. Thus, Zn2+ supplementation may be a simple approach to reducing opioid addiction and dependence.
Hypogonadism in opioid using males in an inner-city cohort: A cross-sectional study
Authors: Wehbeh, MD Leen , Dobs, MD, MHS Adrian S. , Brown, MD, PhD Todd T.
Published: April 2021

Objectives: The link between male hypogonadism and opioids is well-established, but whether there is a difference in the frequency of hypogonadism between heroin and methadone for treatment of opioid use disorder (OUD) has not been determined.Design: Cross-sectional.Setting, patients, and participants: Male drug users and nonusers matched for socioeconomic status between 18 and 65 years, recruited in Baltimore as part of the study of HIV, injection drug use, nutrition, and endocrinology (SHINE). Methods: Hypogonadism was defined as low free testosterone <50 pg/mL. Participants were categorized into three groups based on opioid use: (1) NONE, (2) methadone use as treatment of OUD (METHADONE), and (3) Heroin use (HEROIN). This third group was further divided to mild (MH), and heavy (HH) heroin use. We used multiple logistic regression to examine the association between hypogonadism and different groups.Results: The cohort consisted of 189 men, 94 percent black, average age 43 years, with high HIV (56 percent) and HCV (38 percent) prevalence. 24 percent had hypogonadism. Compared to NONE, there were higher odds of hypogonadism in METHADONE (aOR 3.46; 95 percent CI [1.34,8.93]; p = 0.01) but not in HEROIN. After dividing HEROIN into MH and HH, there were higher odds of hypogonadism in HH compared to NONE (aOR 3.27; 95 percent CI [1.12,9.53]; p = 0.03) but not in MH.Conclusions: Methadone used for treatment of OUD was associated with male hypogonadism similar to heavy heroin use. Targeted hypogonadism screening and treatment may be warranted in this population to reduce its health consequences such as sexual dysfunction, osteoporosis, and abdominal adiposity.
The impact of opioid prescribing reduction interventions on prescribing patterns across orthopedic subspecialties
Authors: Turcotte, PhD, MBA Justin , Crowley, MBA, MS, PT Kevin , Adams, MEd Stephanie , Keblish, MD David , Lashgari, MD Cyrus , Patton, MD, MS Chad , Petre, MD Benjamin , King, MD Paul , Gelfand, MD Jeffrey
Published: April 2021

Objective: To date, the majority of studies have focused on the adverse effect of opioid overutilization on outcomes, risk factors for overutilization and dependence, and the development of procedure-specific guidelines. We present the results of a multiphased approach to reducing opioid prescribing.Design: A retrospective pre-post study of opioid prescriptions across 386,393 patient encounters was conducted. The preintervention cohort included patient encounters from November 2016 to March 2017, and the post-intervention cohort included encounters from April 2017 to October 2019.Setting: Single-institution orthopedic practice.Patients, participants: 386,393 patient encounters.Intervention: Multiple prescribing reduction interventions were implemented from April 2017 to July 2018.Main outcome measure: Average morphine milligram equivalent (MME) per patient encounter.Results: Implementation of the interventions resulted in an average reduction of 15.2 MME per encounter (54.5 percent) compared to the preimplementation cohort (pre: avg. MME = 27.9, SD 113.6; post: avg. MME = 12.7, SD 66.1; p < 0.001). The number of pills per opioid prescription was reduced by 13.4 (29.5 percent) (pre: avg. pill count = 45.5, S.D. 25.1; post: avg. pill count = 32.1, SD 21.1; p < 0.001), and the percent of patients receiving opioids was reduced from 8.3 percent to 5.8 percent (p < 0.001). Prescribing compliance was evaluated for 7,664 surgical encounters, with 98.2 percent of prescriptions meeting stated guidelines; 5.5 percent of these encounters required second prescriptions.Conclusions: The use of a multiphase approach effectively reduced the opioid prescribing patterns of a large orthopedic practice and was successful across subspecialties. This approach provides a template that other institutions may use to reduce opioid overprescribing in orthopedic practices.
Ecosistema de aprendizaje con «realidad aumentada»: posibilidades educativas
Authors: Cabero Almenara Julio , Barroso Osuna Julio
Published: April 2021

Cuando hablamos de «realidad aumentada» (RA), podemos decir que nos encontramos ante una tecnología emergente que está adquiriendo un gran impulso en el terreno educativo. La tecnología de la RA nos ofrece diferentes posibilidades para desplazarnos a contextos de formación fuera de los escenarios tradicionales, interaccionar en tiempo real con la realidad, visualizar fenómenos no perceptibles y comparar un objeto o fenómeno desde diferentes perspectivas. Estos aspectos están provocando que en los últimos cuatro años el número de artículos publicados en el campo de la educación haya aumentado progresivamente. Pero desde nuestro punto de vista, cuando nos referimos a su penetración en el terreno educativo, si no reflexionamos sobre los modelos y paradigmas educativos y teorías educativas y psicológicas que deben dar cobertura a esta tecnología, así como sobre el papel que los docentes y discentes deben jugar con las mismas, nos podemos encontrar con un caso similar al de otras tecnologías que se presentaron como el futuro y no llegaron al presente. Es en torno a estos aspectos sobre lo que reflexionaremos en el presente artículo.
Optimización de la evaluación integral del alumnado: la ofimática al rescate
Authors: Pastor García Artur
Published: April 2021

La evaluación del alumnado se centra principalmente en asignar calificaciones en las diferentes asignaturas con las plataformas educativas que permiten introducir notas numéricas. En algunas se pueden incluir datos de absentismo del alumnado, pero sigue sin haber métodos que permitan una valoración integral tanto de la clase como del alumno. Desarrollar una herramienta que supla esas limitaciones o las complemente se convierte en el objetivo principal de este trabajo. La ofimática pone al servicio de cualquier usuario inmensas posibilidades para obtener una evaluación integral del alumno.Una plantilla de muestra interactiva desarrollada a partir de la ofimática permite dotar al maestro de un instrumento para evaluar cualquier asignatura o clase en parámetros estadísticos. La plantilla se muestra más eficaz que las plataformas educativas actuales en los criterios de mostrar parámetros estadísticos de la clase y de los alumnos, así como a la hora de generar informes individualizados.
Mobile learning multidispositivo en la enseñanza universitaria a distancia
Authors: De la Peña Esteban Francisco David , Burgos García María Concepción , Simón Rodríguez María Antonia
Published: April 2021

La evolución de las tecnologías de la información y la comunicación (TIC) en los últimos años ha tenido un gran efecto en la manera de enfocar la enseñanza, sobre todo en la modalidad de mobile learning. Hoy en día, la mayoría de los estudiantes cuentan con multitud de dispositivos para conectarse a internet y quieren utilizarlos todos para un aprendizaje en cualquier momento y en cualquier lugar. Para afrontar este reto, la Universidad a Distancia de Madrid (UDIMA) se propuso implementar aplicaciones (apps) complementarias al estudio para este entorno multidispositivo. Se comenzó con una prueba piloto realizada para sistema operativo Android y válida tanto para smartphones como para tablets. A partir de ella, el siguiente paso fue el desarrollo de una aplicación web (web app) con diseño web adaptable, que es compatible con la práctica totalidad de los nuevos dispositivos móviles que existen en el mercado. Actualmente, se ha extendido esta iniciativa y ya se cuenta con cinco aplicaciones web para diversas asignaturas tanto de grado como de máster. Los estudiantes creen que son de gran ayuda para el aprendizaje y que aportan valor añadido a la enseñanza. Los módulos de casos prácticos y contenido multimedia son los más valorados. Los estudiantes querrían también un sistema de avisos de la asignatura.
ТӘУЕЛСІЗ МЕМЛЕКЕТТЕР ДОСТАСТЫҒЫ МЕН ҚАЗАҚСТАНДАҒЫ ДЕНСАУЛЫҚ МҮМКІНДІКТЕРІ ШЕКТЕУЛІ АДАМДАРДЫҢ ЖАҒДАЙЫНЫҢ ӘЛЕУМЕТТІК-ЭКОНОМИКАЛЫҚ КӨРСЕТКІШТЕРІ
Authors:   Мирас Университеті, Шымкент, Қазақстан, Бейсенова М.У. ,   e-mail: madina.beisenova@mail.ru, Мархаева Б.А. ,   М. Əуезов атындағы ОҚМУ, Шымкент, Қазақстан, Жусипова Э.Е. ,   Мардан Сапарбаев Институты, Шымкент қ., Қазақстан, Кальменова М.Т. ,   А.Қуатбеков атындағы Халықтар достығы университеті, Шымкент, Қазақстан
Published: April 2021

Осы мақаланың мақсаты - Тəуелсіз Мемлекеттер Достастығы (ТМД) мен Қазақстанда мүмкіндігі шектеулі адамдардың жағдайы туралы статистикалық деректерді талдау, адами капитал компоненттерінің құрамында мүгедектің еңбек əлеуетін қалыптастыру мен дамытуға əсер ететін факторларды анықтау болып табылады. Мүгедектіктің бірінші тобы жəне мүгедектік деңгейі сияқты мүгедектікті сипаттайтын көрсеткіштер қаралды. Бұл ретте Қазақстанда еңбекке қабілетті халық арасында мүгедектікке əсер ететін индикаторлар анықталды, оларға əлеуметтік-экономикалық, медициналық-демографиялық жəне экологиялық факторлар, еңбекті қорғаудың төмен деңгейі, сондай-ақ медициналық қызметтердің төмен сапасы мен жоғары құны жатады. ТМД елдерінде мүгедектіктің негізгі себептері көрсетілген: жалпы сипаттағы аурулар, қан айналымы органдарының ауруларынан мүгедектік, қатерлі ісіктер, психикалық бұзылулар, кəсіби аурулар мен өндірістегі жарақаттар. Қазақстанда мүмкіндігі шектеулі адамдардың жұмысқа орналасуына əсер ететін факторлар жəне осы үдерістегі мемлекет пен бизнестің рөлі келтірілген.
ЭКОНОМИКАЛЫҚ ПРОЦЕСТЕРДІ ҮЙЛЕСТІРУ ЖАҒДАЙЫНДА ҰЛТТЫҚ ЖƏНЕ ХАЛЫҚАРАЛЫҚ ЕСЕП ЖҮЙЕЛЕРІНІҢ ДАМУ ЕРЕКШЕЛІКТЕРІ
Authors:   Л.Н.Гумилев атындағы Еуразия ұлттық университеті, Нұр-Сұлтан, Қазақстан, Сапарбаева С.С. , Жумагалиева Ж.М. ,   Л.Н.Гумилев атындағы Еуразия ұлттық университеті, Нұр-Сұлтан, Қазақстан, Туребекова Б.О. ,   Казақ технология жəне бизнес унивеститеті, Нұр-Сұлтан, Қазақстан
Published: April 2021

Мақалада қаржылық есептілік халықаралық стандарттарының есеп жүйесін стандартизациялау жəне үйлестіру маңызды элементі ретінде орны мен маңызы қарастырылады.Үйлестіру əр елдің бухгалтерлік есеп стандарттарының қоғамдастыққа мүше елдердегі ұқсас стандарттарға сəйкес келүін, яғни бір-біріне қатысты «үйлесімділікті» білдіреді. Бухгалтерлік есеп процедураларын стандарттау деп кез-келген елде қолданатын стандарттардың бірыңғай жиынтығын жасау танылады, оның нəтежесінде ұлттық стандарттарды құрудың қажеті жойылады. Зерттеу барысында заманауи ұйымдардағы есеп қызметін стандарттау жолымен қаржылық есептілікті үйлестірудің қазіргі жай-күйі, қорытындылары мен перспективалары танылды; отандық ұйымдардың қазіргі кезеңдегі қаржылық есептілігін үйлестірудің проблемалары мен оларды шешу жолдары анықталды. Зерттеудің нəтижесінде алынған қорытындылар отандық кəсіпорындардағы қаржылық есептілікті үйлестіру кезінде туындайтын мəселелерді анықтап, оларды шешу тəжірибесінде қолданылуы мүмкін.
CURRENT STATE OF THE WORLD OIL MARKET
Authors:   Al-Farabi Kazakh National University, Almaty, Kazakhstan, Yeshtayeva A.A. ,   e-mail: eshtaeva1998@mail.ru, Dabyltaeva N.E. ,   Al-Farabi Kazakh National University, Almaty, Kazakhstan
Published: April 2021

This paper discusses issues related to the current state of the world oil market. The system of indicators of the development of the world oil market has been determined. Analyzed the current state of the world oil market and changes in it that followed due to the outbreak of coronavirus and the rupture of the OPEC + deal. The modern world market for oil and oil products is one of the key markets in the world economy, which explains the importance of its research in the context of analyzing industry markets. The basic forecast of the development of the world oil market for 2020 is considered. The reasons for the change in the forecast of the oil market development for 2020 are revealed.
UPDATING THE AGRO-INDUSTRIAL COMPLEX SYSTEM IN THE CONTEXT OF THE REFORM
Authors:   Shymkent University, Shymkent, Kazakhstan, Kuashbay S. ,   e-mail: turebaevaz@mail.ru, Abdikеrimova G. I. ,   Shymkent University, Shymkent, Kazakhstan, Turebayeva J. K. ,   Shymkent University, Shymkent, Kazakhstan, Jazdykbayeva D.P. ,   Mardan Saparbayev Institute, Shymkent, Kazakhstan
Published: April 2021

The research is devoted to the issues of active development of the agro-industrial complex in Kazakhstan within the framework of modern reform. Originality of the research. The updated structure of the resource management system of the agro-industrial complex of Kazakhstan is proposed, the subsystems and blocks included in it, their content and measures for formation are defined. Research result. The prospects for the development of the agro-industrial complex and methods for achieving the goals of the government of Kazakhstan are presented. Effective work of the agro-industrial sector of the economy of Kazakhstan is possible only with active state support at the national and regional levels.
METHODS OF RISK MINIMIZATION IN THE DEVELOPMENT OF AGRO-INDUSTRIAL ENTREPRENEURSHIP
Authors:   Zhetysu University n. a. I. Zhansugurov NP JSC, Taldykorgan, Kazakhstan, Saparov Ye. ,   e-mail:king_bara@mail.ru, Tuleshova G. ,   Zhetysu University n. a. I. Zhansugurov NP JSC, Taldykorgan, Kazakhstan, Saparova A. ,   Zhetysu University n. a. I. Zhansugurov NP JSC, Taldykorgan, Kazakhstan
Published: April 2021

In the conditions of modern market relations, the activity of any industrial enterprise is impossible without risks. It is almost impossible to avoid risk in production activities, so the main task is to assess the possible risk and develop measures to prevent it. Agro-industrial production is most affected by factors that lead to risks. Agroindustrial production is the basis of the country's life, and is a producer and supplier of vital products. This article examines the impact of risks on the results of agricultural production, identifies the stages of risk management, as well as various approaches to risk classification, analyzes the main causes and consequences of risks in agricultural enterprises.
FORMATION AND DEVELOPMENT ECONOMY OF THE UNITED ARAB EMIRATES
Authors:   Almaty Academy of Economics and Statistics, Almaty, Kazakhstan, Seidakhmetova F. ,   e-mail: favziy@inbox.ru
Published: April 2021

The article discusses the features of the formation and development of the economy of the United Arab Emirates. The authors describe in detail the stages of the historical development of the UAE, as well as the legal aspects developed by the government of the UAE in modern conditions.
КӘСІПОРЫННЫҢ ЭКОНОМИКАЛЫҚ ҚАУІПСІЗДІК ЖҮЙЕСІНДЕГІ ТӘУЕКЕЛ МЕНЕДЖМЕНТІНІҢ РӨЛІ
Authors:   М. Х. Дулати атындағы Тараз өңірлік университеті, Тараз, Қазақстан, Байтиленова Е.С. ,   e-mail: nailya0478@mail.ru, Сугирова Г.С. ,   Алматы Экономика жəне статистика академиясы, Алматы, Қазақстан, Нұртаева А. К. ,   І.Жансүгіров атындағы Жетісу университеті, Талдықорған,Қазақстан, Абдыкалык С. Е. ,   Алматы Экономика жəне статистика академиясы, Алматы, Қазақстан
Published: April 2021

Кəсіпкерлік қызметтің тəуекел-менеджментінің теориялық мəселелері қаралды; кəсіпкерлік құрылымдардың өндірістік-шаруашылық қызметін басқару процесінде тəуекел жағдайларының туындау себептері зерттелді. Кəсіпкерлік құрылымдардың бəсекеге қабілеттілігін арттыруды қамтамасыз ететін фактор ретінде кəсіпкерлік қызметтің ішкі Тəуекелдерін басқару жүйесін қалыптастыру кезінде процестік тəсілді пайдалану ұсынылады. Бұл тəсіл ұйымда қауіпті жағдайлардың пайда болуы сөзсіз болатын процестер мен процестерді бөлуден тұрады. Кəсіпорында тəуекелдерді басқаруды ұйымдастыру жəне қою жүйесі ұсынылған, ол қаржылық менеджментпен қатар қазіргі уақытта компанияны тиімді басқаруды ұйымдастыруға мүмкіндік беретін негізгі компонент болып табылады. Тəуекелдерді басқару жүйесінің орталығында теориялық ұсыныстарға сəйкес келетін жəне ішкі жəне сыртқы теңдестірілген, сонымен қатар зиянды болдырмауға ғана емес, сонымен қатар компанияның құнын құруға бағытталған тəуекелдерді анықтау процедурасы жатыр.
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНЫҢ ТАМАҚ ӨНЕРКӘСІБІНІҢ ЖАЙ-КҮЙІН ТАЛДАУ
Authors:   Д.Серікбаев атындағы Шығыс Қазақстан техникалық университеті, Өскемен, Қазақстан, Суйеубаева С.Н. , Мадиярова Э.С. ,   Д.Серікбаев атындағы Шығыс Қазақстан техникалық университеті, Өскемен, Қазақстан, Апышева А.А. ,   С.Аманжолов атындағы Шығыс Қазақстан университеті, Өскемен, Қазақстан
Published: April 2021

Тамақ өнеркəсібі кез келген елдің экономикасы үшін өте маңызды сала болып табылады, өйткені тамақ өнімдерін өндіру халықтың шұғыл жəне бірінші кезекті қажеттіліктерін қанағаттандырумен тікелей байланысты. Өзнің құрамына 40-тан астам мамандандырылған салалар, кіші салалар мен жекелеген өндірістерді біріктіретін тамақ өнеркəсібі – ұлттық экономиканың маңызды қоғамдық салалардың бірі болып табылады. Қазақстандық азық-түлік нарығын зерттеудің өзектілігі оны талдау кезінде алынуы мүмкін нəтижелермен расталады. Статистикалық деректерді өңдеу жəне оларды жүйелеу графиктер мен кестелер түрінде ұсынылған. Негізгі көрсеткіштер қазіргі заманғы азық-түлік өнімдері нарығының импортқа тəуелділігін айқындайды, бұл шикізаттық бағыттағы импорттық өнімдердің ұлғаюына байланысты болған. Экспортқа тауарлардың аз түрлері жіберіледі, негізінен ет жəне балық өнеркəсібінің өнімдері. Қазақстан аумағында тамақ өнеркəсібі кəсіпорындарының бір бөлігі негізінен тұтыну қағидаты бойынша орналасқан, екінші бөлігі шикізат базасымен тығыз байланысты шоғырландырылған.