bluuebunny/crossref_metadata_2025 huggingface dataset:
The Analysis of Public Funds Utilization Efficiency for Climate Neutrality in the European Union Countries
Authors: Dębkowska Katarzyna , Dymek Łukasz , Kutwa Krzysztof , Perło Dariusz , Perło Dorota , Rogala Wojciech , Ryciuk Urszula , Szewczuk-Stępień Marzena
Published: January 2022

The aim of this article was to assess the efficiency of the utilization of public funds for climate neutrality. It was concluded that the data gathered in public statistics are not adapted to current challenges and hinder the direct measurement of climate policy objective implementation progress. Due to that, an innovative approach to public intervention efficiency analysis was proposed for the sake of decreasing CO2 emission in 27 European Union (EU) countries, based on Data Envelopment Analysis (DEA) method and soft modeling. Statistical data are derived from the Eurostat database and pertain to the years 2005–2019. It was demonstrated that activity efficiency of the particular EU countries on climate neutrality varied and that together with the increase in public funds spent on environmental protection, the growth of effects in the field of reaching climate neutrality objectives was not observed. The greatest positive impact on achieving climate neutrality objectives was revealed for activities connected with building renewable sources of energy (RES) and there was no correlation detected for expenditures connected with transport infrastructure, which means that public funds used for their construction did not influence climate neutrality. It was established that, in the analyzed period, the decisions on allocating public funds were not taken on the basis of the expected amount of reduction in relation to the volume of outlays. In order to track the reasons for detected inefficiency, 52 projects were analyzed within the case study, which covered 3738 investments in the replacement of heating sources in one region of Poland. It was revealed that the efficiency of those investments varies; however, due to the full availability of data of the acquired results and outlays devoted to them, a synthetic index of efficiency measurement was established that presents the amount of CO2 reduction for EUR 1. When comparing the analyses carried out on macro and micro scales, it was observed that on the scale of the EU, there is a lack of uniform measurements or benchmarks of projects in the field of CO2 emissions reduction. Meanwhile, from the whole EU’s perspective, it should be reasonable to undertake projects with the highest economic efficiency, irrespective of political and geographical aspects. The results obtained should be utilized by decision-makers to elaborate reference methodologies and good practices in order to successfully implement climate objectives and especially the Energy Performance of Buildings Directive (EPBD). What should be established are universal, on the EU scale, measurements and rules for gathering and counting data as well as benchmarks for the particular project types.
Evaluating the Potential Contribution of District Heating to the Flexibility of the Future Italian Power System
Authors: Magni Chiara , Quoilin Sylvain , Arteconi Alessia
Published: January 2022

Flexibility is crucial to enable the penetration of high shares of renewables in the power system while ensuring the security and affordability of the electricity dispatch. In this regard, heat–electricity sector coupling technologies are considered a promising solution for the integration of flexible devices such as thermal storage units and heat pumps. The deployment of these devices would also enable the decarbonization of the heating sector, responsible for around half of the energy consumption in the EU, of which 75% is currently supplied by fossil fuels. This paper investigates in which measure the diffusion of district heating (DH) coupled with thermal energy storage (TES) units can contribute to the overall system flexibility and to the provision of operating reserves for energy systems with high renewable penetration. The deployment of two different DH supply technologies, namely combined heat and power units (CHP) and large-scale heat pumps (P2HT), is modeled and compared in terms of performance. The case study analyzed is the future Italian energy system, which is simulated through the unit commitment and optimal dispatch model Dispa-SET. Results show that DH coupled with heat pumps and CHP units could enable both costs and emissions related to the heat–electricity sector to be reduced by up to 50%. DH systems also proved to be a promising solution to grant the flexibility and resilience of power systems with high shares of renewables by significantly reducing the curtailment of renewables and cost-optimally providing up to 15% of the total upward reserve requirements.
Switching Frequency Effects on the Efficiency and Harmonic Distortion in a Three-Phase Five-Level CHBMI Prototype with Multicarrier PWM Schemes: Experimental Analysis
Authors: Busacca Alessandro , Di Tommaso Antonino Oscar , Miceli Rosario , Nevoloso Claudio , Schettino Giuseppe , Scaglione Gioacchino , Viola Fabio , Colak Ilhami
Published: January 2022

The current climatic scenario requires the use of innovative solutions to increase the production of electricity from renewable energy sources. Multilevel Power Inverters are a promising solution to improve the penetration of renewable energy sources into the electrical grid. Moreover, the performance of MPIs is a function of the modulation strategy employed and of its features (modulation index and switching frequency). This paper presents an extended and experimental analysis of three-phase five-level Cascaded H-Bridges Multilevel Inverter performance in terms of efficiency and harmonic content considering several MC PWM modulation strategies. In detail, the CHBMI performance is analyzed by varying the modulation index and the switching frequency. For control purposes, the NI System On Module sbRIO-9651 control board, a dedicated FPGA-based control board for power electronics and drive applications programmable in the LabVIEW environment, is used. The paper describes the modulation strategies implementation, the test bench set-up, and the experimental investigations carried out. The results obtained in terms of Total Harmonic Distorsion (THD) and efficiency are analyzed, compared, and discussed.
Statistical and Artificial Neural Networks Models for Electricity Consumption Forecasting in the Brazilian Industrial Sector
Authors: Leite Coelho da Silva Felipe , da Costa Kleyton , Canas Rodrigues Paulo , Salas Rodrigo , López-Gonzales Javier Linkolk
Published: January 2022

Forecasting the industry’s electricity consumption is essential for energy planning in a given country or region. Thus, this study aims to apply time-series forecasting models (statistical approach and artificial neural network approach) to the industrial electricity consumption in the Brazilian system. For the statistical approach, the Holt–Winters, SARIMA, Dynamic Linear Model, and TBATS (Trigonometric Box–Cox transform, ARMA errors, Trend, and Seasonal components) models were considered. For the approach of artificial neural networks, the NNAR (neural network autoregression) and MLP (multilayer perceptron) models were considered. The results indicate that the MLP model was the one that obtained the best forecasting performance for the electricity consumption of the Brazilian industry under analysis.
Variable Speed Diesel Generators: Performance and Characteristic Comparison
Authors: Mobarra Mohammadjavad , Rezkallah Miloud , Ilinca Adrian
Published: January 2022

Diesel generators (DGs) are set to work as a backup during power outages or support the load in remote areas not connected to the national grid. These DGs are working at a constant speed to produce reliable AC power, while electrical energy demand fluctuates according to instantaneous needs. High electric loads occur only for a few hours a day in remote areas, resulting in oversizing DGs. During a low load operation, DGs face poor fuel efficiency and condensation of fuel residues on the walls of engine cylinders that increase friction and premature wear. One solution to increase combustion efficiency at low electric loads is to reduce diesel engine (DE) speed to its ideal regime according to the mechanical torque required by the electrical generator. Therefore, Variable Speed Diesel Generators (VSDGs) allow the operation of the diesel engine at an optimal speed according to the electrical load but require additional electrical equipment and control to maintain the power output to electrical standards. Variable speed technology has shown a significant reduction of up to 40% fuel consumption, resulting in low GHG emissions and operating costs compared to a conventional diesel generator. This technology also eliminates engine idle time during a low load regime to have a longer engine lifetime. The main objective of this survey paper is to present the state of the art of the VSDG technologies and compare their performance in terms of fuel savings, increased engine lifetime, and reduced greenhouse gases (GHG) emissions. Various concepts and the latest VSDG technologies have been evaluated in this paper based on their performance appraisal and degree of innovation.
Influence of Optic Cable Construction Parts on Recovery Process after Gamma Irradiation
Authors: Šaršounová Zuzana , Plaček Vít , Prajzler Václav , Masopustová Kateřina , Havránek Petr
Published: January 2022

Fibre optic cables are widely used as communication cables in Instrumentation and Control (I&C) systems. In the case of nuclear power plants (NPPs), using optic cables in mild environments outside of containment areas are very common. However, at present, there is a need for fibre optic cables to be used in containment areas, i.e., with radiation. An optical fibre consists of a highly transparent core that possesses a higher refractive index than the surrounding transparent cladding, which possesses a lower refractive index. Most optical fibres are manufactured from glass (silica with required dopants) which is created at high temperatures from the reaction between gasses. The glass used in optical fibres is sensitive; it becomes dark during exposure to radiation, which compromises the optic functions. That is why there has been a slow infiltration of optic cable in NPP containment areas. Radiation resistant optic fibres have been developed. Although these fibres are called “radiation resistant,” they go through a darkening process (absorbance increase) as well, but not as quickly. Immediately after the irradiation has stopped, a recovery process starts in the glass structure. During this period, optical losses of the glass improve, but not to the original level as before the irradiation. During the testing of optic cables for the installation in nuclear power plant containment areas, we observed an unusual recovery process. In the beginning, a healing effect was observed. However, after a few days of recovery, the healing process stopped, and the trend changed again as a worsening of the optical properties was observed. This paper describes experiments which explain the reasons for such an unexpected behaviour.
A Study of Control Methodologies for the Trade-Off between Battery Aging and Energy Consumption on Electric Vehicles with Hybrid Energy Storage Systems
Authors: Mallon Kevin , Assadian Francis
Published: January 2022

Hybrid and electric vehicle batteries deteriorate from use due to irreversible internal chemical and mechanical changes, resulting in decreased capacity and efficiency of the energy storage system. This article investigates the modeling and control of a lithium-ion battery and ultracapacitor hybrid energy storage system for an electric vehicle for improved battery lifespan and energy consumption. By developing a control-oriented aging model for the energy storage components and integrating the aging models into an energy management system, the trade-off between battery degradation and energy consumption can be minimized. This article produces an optimal aging-aware energy management strategy that controls both battery and ultracapacitor aging and compares these results to strategies that control only battery aging, strategies that control battery aging factors but not aging itself, and non-optimal benchmark strategies. A case study on an electric bus with variously-sized hybrid energy storage systems shows that a strategy designed to control battery aging, ultracapacitor aging, and energy losses simultaneously can achieve a 28.2% increase to battery lifespan while requiring only a 7.0% decrease in fuel economy.
An Automatic Procedure for Overheated Idler Detection in Belt Conveyors Using Fusion of Infrared and RGB Images Acquired during UGV Robot Inspection
Authors: Dabek Przemyslaw , Szrek Jaroslaw , Zimroz Radoslaw , Wodecki Jacek
Published: January 2022

Complex mechanical systems used in the mining industry for efficient raw materials extraction require proper maintenance. Especially in a deep underground mine, the regular inspection of machines operating in extremely harsh conditions is challenging, thus, monitoring systems and autonomous inspection robots are becoming more and more popular. In the paper, it is proposed to use a mobile unmanned ground vehicle (UGV) platform equipped with various data acquisition systems for supporting inspection procedures. Although maintenance staff with appropriate experience are able to identify problems almost immediately, due to mentioned harsh conditions such as temperature, humidity, poisonous gas risk, etc., their presence in dangerous areas is limited. Thus, it is recommended to use inspection robots collecting data and appropriate algorithms for their processing. In this paper, the authors propose red-green-blue (RGB) and infrared (IR) image fusion to detect overheated idlers. An original procedure for image processing is proposed, that exploits some characteristic features of conveyors to pre-process the RGB image to minimize non-informative components in the pictures collected by the robot. Then, the authors use this result for IR image processing to improve SNR and finally detect hot spots in IR image. The experiments have been performed on real conveyors operating in industrial conditions.
Bond between Fibre-Reinforced Polymer Tubes and Sea Water Sea Sand Concrete: Mechanisms and Effective Parameters: Critical Overview and Discussion
Authors: Luck Johanna Dorothea , Bazli Milad , Rajabipour Ali
Published: January 2022

Using fibre-reinforced polymers (FRP) in construction avoids corrosion issues associated with the use of traditional steel reinforcement, while seawater and sea sand concrete (SWSSC) reduces environmental issues and resource shortages caused by the production of traditional concrete. The paper gives an overview of the current research on the bond performance between FRP tube and concrete with particular focus on SWSSC. The review follows a thematic broad-to-narrow approach. It reflects on the current research around the significance and application of FRP and SWSSC and discusses important issues around the bond strength and cyclic behaviour of tubular composites. A review of recent studies of bond strength between FRP and concrete and steel and concrete under static or cyclic loading using pushout tests is presented. In addition, the influence of different parameters on the pushout test results are summarised. Finally, recommendations for future studies are proposed.
Acacia dealbata Link. Aboveground Biomass Assessment: Sustainability of Control and Eradication Actions to Reduce Rural Fires Risk
Authors: Nunes Leonel , Meireles Catarina , Gomes Carlos , Ribeiro Nuno
Published: January 2022

Invasive species are an environmental problem affecting worldwide ecosystems. In the case of Acacia dealbata Link., the negative impacts affect the productivity of the forests due to the competition established with native species while contributing to a significant increment in the available fuel load, increasing the risk of fire. In Portugal, chemical and mechanical methods are mostly used in the control of these species. However, the costs are often unsustainable in the medium term, being abandoned before completing the tasks, allowing the recovery of the invasive species. The establishment of value chains for the biomass resulting from these actions was pointed out by several authors as a solution for the sustainability of the control process, as it contributes to reducing costs. However, the problems in quantifying the biomass availability make it challenging to organize and optimize these actions. This work, which started from a dendrometrical analysis carried out in stands of A. dealbata, created a model to assess woody biomass availability. The model proved to be statistically significant for stands with trees younger than 20 years old. However, the amount of data collected and the configuration of the settlements analyzed do not allow extrapolation of the model presented to older settlements.
Mapping and Assessing Commercial Fisheries Services in the Lithuanian Part of the Curonian Lagoon
Authors: Ivanauskas Edgaras , Skersonas Andrius , Andrašūnas Vaidotas , Elyaagoubi Soukaina , Razinkovas-Baziukas Artūras
Published: January 2022

The spatial distribution of biomass of main commercial fish species was mapped to estimate the supply of a provisioning fishery service in the Curonian lagoon. Catch per unit effort (CPUE) was used as a proxy to estimate the efficiency of commercial fishing and, subsequently, the potential biomass of fishes. The relationship between distinctive characteristics of the fishing areas and corresponding commercial catches and CPUE was analyzed using multivariate analysis. The total catch values and CPUE used in the analyses were derived from the official commercial fishery records. RDE analysis was used to assess the variation of both catch and CPUE of commercial fish species, while the percentages of bottom sediment type coverage, average depth, annual salinity, and water residence time in each of the fishing squares were used as explanatory variables. This distance e-based redundancy analysis allowed for the use of non-Euclidean dissimilarity indices. Fisheries data spatial distribution map indicated the lack of coherence between the spatial patterns of commercial catches and CPUE distribution in the northern part of the lagoon. Highest CPUE values were estimated in the central-eastern part of the lagoon as compared to the western part of the lagoon where CPUE values were substantially lower. Both total catch and CPUE appeared not to be related to the type of bottom habitats statistically while being spatially correlated in-between. However, the impact of salinity and water residence time calculated using the 3D hydraulic circulation model on the distribution of both CPUE and commercial catches was statistically significant.
Lipid Profiles in Preliminary Germinated Brown Rice Beverages Compared to Non-Germinated Brown and White Rice Beverages
Authors: Beaulieu John C. , Moreau Robert A. , Powell Michael J. , Obando-Ulloa Javier M.
Published: January 2022

Brown rice is nutritionally superior to white rice, yet oil rancidity can be problematic during processing and storage regarding sensory attributes. Germinating brown rice is known to generally increase some health-promoting compounds. In response to increasing the consumption of plant-based beverages, we sprouted unstabilized brown rice, using green technologies and saccharification enzymes for value-added beverages. ‘Rondo’ paddy rice was dehulled, sorted and germinated, and beverages were produced and compared against non-germinated brown and white brewers rice beverages. The preliminary germinated brown rice beverage contained significantly higher concentrations of total lipids, diacylglycerols, triacylglycerols, free sterols, phytosterol esters and oryzanols than both non-germinated brown and white rice beverages. White rice beverages had significantly higher free fatty acids. Significant lipid losses occurred during sieving, yet novel germinated brown rice beverages contained appreciable levels of valuable health-beneficial lipids, which appeared to form natural emulsions. Further pilot plant investigations should be scaled-up for pasteurization and adjusted through emulsification to ameliorate sieving losses.
High Pressure Processing Applications in Plant Foods
Authors: Houška Milan , Silva Filipa Vinagre Marques , Evelyn  , Buckow Roman , Terefe Netsanet Shiferaw , Tonello Carole
Published: January 2022

High pressure processing (HPP) is a cold pasteurization technology by which products, prepacked in their final package, are introduced to a vessel and subjected to a high level of isostatic pressure (300–600 MPa). High-pressure treatment of fruit, vegetable and fresh herb homogenate products offers us nearly fresh products in regard to sensorial and nutritional quality of original raw materials, representing relatively stable and safe source of nutrients, vitamins, minerals and health effective components. Such components can play an important role as a preventive tool against the start of illnesses, namely in the elderly. An overview of several food HPP products, namely of fruit and vegetable origin, marketed successfully around the world is presented. Effects of HPP and HPP plus heat on key spoilage and pathogenic microorganisms, including the resistant spore form and fruit/vegetable endogenous enzymes are reviewed, including the effect on the product quality. Part of the paper is devoted to the industrial equipment available for factories manufacturing HPP treated products.
Effects of Dual-Frequency Ultrasound-Assisted Thawing Technology on Thawing Rate, Quality Properties, and Microstructure of Large Yellow Croaker (Pseudosciaena crocea)
Authors: Cheng Hao , Bian Chuhan , Chu Yuanming , Mei Jun , Xie Jing
Published: January 2022

This research evaluated the effects of dual-frequency ultrasound-assisted thawing (UAT) on the thawing time, physicochemical quality, water-holding capacity (WHC), microstructure, and moisture migration and distribution of large yellow croaker. Water thawing (WT), refrigerated thawing (RT), and UAT (single-frequency: 28 kHz (SUAT-28), single-frequency: 40 kHz (SUAT-40), dual-frequency: 28 kHz and 40 kHz (DUAT-28/40)) were used in the current research. Among them, the DUAT-28/40 treatment had the shortest thawing time, and ultrasound significantly improved the thawing rate. It also retained a better performance from the samples, such as color, texture, water-holding capacity and water distribution, and inhibited disruption of the microstructure. In addition, a quality property analysis showed that the pH, total volatile basic nitrogen (TVB-N), and K value were the most desirable under the DUAT-28/40 treatment, as well as this being best for the flavor of the samples. Therefore, DUAT-28/40 treatment could be a possible thawing method because it improves the thawing rate and maintains the quality properties of large yellow croaker.
Adsorption Factors in Enhanced Coal Bed Methane Recovery: A Review
Authors: Tambaria Theodora Noely , Sugai Yuichi , Nguele Ronald
Published: January 2022

Enhanced coal bed methane recovery using gas injection can provide increased methane extraction depending on the characteristics of the coal and the gas that is used. Accurate prediction of the extent of gas adsorption by coal are therefore important. Both experimental methods and modeling have been used to assess gas adsorption and its effects, including volumetric and gravimetric techniques, as well as the Ono–Kondo model and other numerical simulations. Thermodynamic parameters may be used to model adsorption on coal surfaces while adsorption isotherms can be used to predict adsorption on coal pores. In addition, density functional theory and grand canonical Monte Carlo methods may be employed. Complementary analytical techniques include Fourier transform infrared, Raman spectroscopy, XR diffraction, and 13C nuclear magnetic resonance spectroscopy. This review summarizes the cutting-edge research concerning the adsorption of CO2, N2, or mixture gas onto coal surfaces and into coal pores based on both experimental studies and simulations.
Curcuminoid Co-Loading Platinum Heparin-Poloxamer P403 Nanogel Increasing Effectiveness in Antitumor Activity
Authors: Nguyen Ngoc The , Bui Quynh Anh , Nguyen Hoang Huong Nhu , Nguyen Tien Thanh , Ly Khanh Linh , Tran Ha Le Bao , Doan Vu Nguyen , Nhi Tran Thi Yen , Nguyen Ngoc Hoa , Nguyen Ngoc Hao , Tran Ngoc Quyen , Nguyen Dinh Trung
Published: January 2022

Nanosized multi-drug delivery systems provide synergistic effects between drugs and bioactive compounds, resulting in increased overall efficiency and restricted side effects compared to conventional single-drug chemotherapy. In this study, we develop an amphiphilic heparin-poloxamer P403 (HP403) nanogel that could effectively co-load curcuminoid (Cur) and cisplatin hydrate (CisOH) (HP403@CisOH@Cur) via two loading mechanisms. The HP403 nanogels and HP403@CisOH@Cur nanogels were closely analyzed with 1H-NMR spectroscopy, FT-IR spectroscopy, TEM, and DLS, exhibiting high stability in spherical forms. In drug release profiles, accelerated behavior of Cur and CisOH at pH 5.5 compared with neutral pH was observed, suggesting effective delivery of the compounds in tumor sites. In vitro studies showed high antitumor activity of HP403@CisOH@Cur nanogels, while in vivo assays showed that the dual-drug platform prolonged the survival time of mice and prevented tail necrosis. In summary, HP403@CisOH@Cur offers an intriguing strategy to achieve the cisplatin and curcumin synergistic effect in a well-designed delivery platform that increases antitumor effectiveness and overcomes undesired consequences caused by cisplatin in breast cancer treatment.
Cyanogenesis in the Sorghum Genus: From Genotype to Phenotype
Authors: Cowan Max , Møller Birger Lindberg , Norton Sally , Knudsen Camilla , Crocoll Christoph , Furtado Agnelo , Henry Robert , Blomstedt Cecilia , Gleadow Roslyn M.
Published: January 2022

Domestication has resulted in a loss of genetic diversity in our major food crops, leading to susceptibility to biotic and abiotic stresses linked with climate change. Crop wild relatives (CWR) may provide a source of novel genes potentially important for re-gaining climate resilience. Sorghum bicolor is an important cereal crop with wild relatives that are endemic to Australia. Sorghum bicolor is cyanogenic, but the cyanogenic status of wild Sorghum species is not well known. In this study, leaves of wild species endemic in Australia are screened for the presence of the cyanogenic glucoside dhurrin. The direct measurement of dhurrin content and the potential for dhurrin-derived HCN release (HCNp) showed that all the tested Australian wild species were essentially phenotypically acyanogenic. The unexpected low dhurrin content may reflect the variable and generally nutrient-poor environments in which they are growing in nature. Genome sequencing of six CWR and PCR amplification of the CYP79A1 gene from additional species showed that a high conservation of key amino acids is required for correct protein function and dhurrin synthesis, pointing to the transcriptional regulation of the cyanogenic phenotype in wild sorghum as previously shown in elite sorghum.
Review of the Forensic Applicability of Biostatistical Methods for Inferring Ancestry from Autosomal Genetic Markers
Authors: Tvedebrink Torben
Published: January 2022

The inference of ancestry has become a part of the services many forensic genetic laboratories provide. Interest in ancestry may be to provide investigative leads or identify the region of origin in cases of unidentified missing persons. There exist many biostatistical methods developed for the study of population structure in the area of population genetics. However, the challenges and questions are slightly different in the context of forensic genetics, where the origin of a specific sample is of interest compared to the understanding of population histories and genealogies. In this paper, the methodologies for modelling population admixture and inferring ancestral populations are reviewed with a focus on their strengths and weaknesses in relation to ancestry inference in the forensic context.
ICESat-2 Applications for Investigating Emerging Volcanoes
Authors: Simurda Christine , Magruder Lori A. , Markel Jonathan , Garvin James B. , Slayback Daniel A.
Published: January 2022

Submarine volcanism in shallow waters (<100 m), particularly in remote settings, is difficult to monitor quantitatively and, in the rare formation of islands, it is challenging to understand the rapid-paced erosion. However, these newly erupted volcanic islands become observable to airborne and/or satellite remote sensing instruments. NASA’s ICESat-2 satellite laser altimeter, combined with visible imagery (optical and microwave), provide a novel method of evaluating the elevation characteristics of newly emerged volcanoes and their subaerial eruption products. Niijima Fukutoku-Okanoba (NFO) is a submarine volcano 1300 km south of Tokyo (Ogasawara Archipelago of Japan) that periodically breaches the ocean surface to create new islands that are subsequently eroded. The recent eruption in August 2021 is a rare opportunity to investigate this island evolution using high-resolution satellite datasets with geodetic-quality ICESat-2 altimetry. Lansdat-8 and Planet imagery provide a qualitative analysis of the exposed volcanic deposits, while ICESat-2 products provide elevation profiles necessary to quantify the physical surface structures. This investigation determines an innovative application for ICESat-2 data in evaluating newly emerged islands and how the combination of satellite remote sensing (visible and lidar) to investigate these short-lived volcanic features can improve our understanding of the volcanic island system in ways not previously possible.
Explanation and Application of the Evolving Contact Traction Fields in Shallow Foundation Systems
Authors: Taylor Adam G. , Chung Jae H.
Published: January 2022

The present paper provides a qualitative discussion of the evolution of contact traction fields beneath rigid shallow foundations resting on granular materials. A phenomenological similarity is recognized in the measured contact traction fields of rigid footings and at the bases of sandpiles. This observation leads to the hypothesis that the stress distributions are brought about by the same physical phenomena, namely the development of arching effects through force chains and mobilized intergranular friction. A set of semi-empirical equations are suggested for the normal and tangential components of this contact traction based on past experimental measurements and phenomenological assumptions of frictional behaviors at the foundation system scale. These equations are then applied to the prescribed boundary conditions for the analysis of the settlement, resistance, and stress fields in supporting granular materials beneath the footing. A parametric sensitivity study is performed on the proposed modelling method, highlighting solutions to the boundary-value problems in an isotropic, homogeneous elastic half-space.
Evidence of On-Going Disparate Levels of Care for South Asian Patients with Inflammatory Bowel Disease in the United Kingdom during the Quinquennium 2015–2019
Authors: Farrukh Affifa , Mayberry John F.
Published: January 2022

Over the last decade, there have been a number of studies which have documented disparate levels of care in the management of inflammatory bowel disease amongst various minority communities in the UK. Similar findings had previously been described in the USA, where access to biologics has been an issue. In this study, data on admissions to hospital of South Asian and White British patients with inflammatory bowel disease between 2015 and 2019 were collected from 12 National Health Service (NHS) trusts in England, three Health Boards in Wales and two Scottish health organizations using Freedom of Information requests. The analyses of data were based on the assumption that inflammatory bowel disease (IBD) has the same prevalence in the South Asian community and the White British community in the UK. Comparisons were made between the proportion of hospitalised patients who were South Asian and the proportion who were White British in the local community using a z statistic. In Leicester, Bradford, Croydon and Lothian, the proportion of patients from the South Asian community admitted to hospital was significantly greater than the proportion from the local White British community, which is consistent with the greater frequency and severity of the disease in the South Asian community in the UK. However, in Coventry, Wolverhampton, Walsall, Acute Pennine Trust in the north-west of England, Barking, Havering and Redbridge and Glasgow, South Asian patients were significantly under-represented, indicating significant issues with access to hospital-based healthcare for inflammatory bowel disease. This study provides evidence of on-going evidence of disparate levels of care for patients from a South Asian background, with inflammatory bowel disease being underserved by a number of NHS Trusts, Health Boards and comparable organisations. When there is on-going failure to achieve the objectives of the NHS of achieving equality in the delivery of care, it is critical to introduce effective policies which will alter the in-built inertia to change within such organisations.
Giant Sternal Chondrosarcoma in a 50-Year-Old Patient
Authors: Pavelescu Cezar , Bebliuc Alexandru , Asmarandei Rareș , Safta Maria Sabina , Zaharia Ondin , Costache Victor Sebastian , Molnar Adrian , Gheorghiță Daniela , Voica Cristian , Moldovan Horațiu
Published: January 2022

Chondrosarcomas represent approximately 20% of primary malignant bone cancers, being known as the most frequent neoplasia of the anterior thoracic wall. In our case, we present a case of a primary sternal chondrosarcoma in a 50-year-old female patient that has been polychemiotherapy and radiotherapy treated for breast cancer. Despite the initial treated malignancy of breast cancer in the personal pathologic history of the patient, it was discovered that the sternal tumor was not a metastatic disease from the breast neoplasm. After multiple investigations, the patient was successfully treated for the sternal chondrosarcoma after a radical sternal resection with a chest wall reconstruction completed with two titanium plates that were anchored on the ribs and with the placement of methyl methacrylate mesh.
Information Security in Medical Robotics: A Survey on the Level of Training, Awareness and Use of the Physiotherapist
Authors: Monoscalco Lisa , Simeoni Rossella , Maccioni Giovanni , Giansanti Daniele
Published: January 2022

Cybersecurity is becoming an increasingly important aspect to investigate for the adoption and use of care robots, in term of both patients’ safety, and the availability, integrity and privacy of their data. This study focuses on opinions about cybersecurity relevance and related skills for physiotherapists involved in rehabilitation and assistance thanks to the aid of robotics. The goal was to investigate the awareness among insiders about some facets of cybersecurity concerning human–robot interactions. We designed an electronic questionnaire and submitted it to a relevant sample of physiotherapists. The questionnaire allowed us to collect data related to: (i) use of robots and its relationship with cybersecurity in the context of physiotherapy; (ii) training in cybersecurity and robotics for the insiders; (iii) insiders’ self-assessment on cybersecurity and robotics in some usage scenarios, and (iv) their experiences of cyber-attacks in this area and proposals for improvement. Besides contributing some specific statistics, the study highlights the importance of both acculturation processes in this field and monitoring initiatives based on surveys. The study exposes direct suggestions for continuation of these types of investigations in the context of scientific societies operating in the rehabilitation and assistance robotics. The study also shows the need to stimulate similar initiatives in other sectors of medical robotics (robotic surgery, care and socially assistive robots, rehabilitation systems, training for health and care workers) involving insiders.
Cost-Effectiveness of Upper Extremity Dry Needling in Chronic Stroke
Authors: Fernández-Sanchis Daniel , Brandín-de la Cruz Natalia , Jiménez-Sánchez Carolina , Gil-Calvo Marina , Herrero Pablo , Calvo Sandra
Published: January 2022

Introduction: Dry needling is a non-pharmacological approach that has proven to be effective in different neurological conditions. Objective: The aim of this study was to evaluate the cost-effectiveness of a single dry needling session in patients with chronic stroke. Methods: A cost-effectiveness analysis was performed based on a randomized controlled clinical trial. The results obtained from the values of the EuroQol-5D questionnaire and the Modified Modified Ashworth Scale were processed in order to obtain the percentage of treatment responders and the quality-adjusted life years (QALYs) for each alternative. The cost analysis was that of the hospital, clinic, or health center, including the equipment and physiotherapist. The cost per respondent and the incremental cost-effectiveness ratio of each alternative were assessed. Results: Twenty-three patients with stroke were selected. The cost of DN treatment was EUR 14.96, and the data analysis showed a favorable cost-effectiveness ratio of both EUR/QALY and EUR/responder for IG, although the sensitivity analysis using limit values did not confirm the dominance (higher effectiveness with less cost) of the dry needling over the sham dry needling. Conclusions: Dry needling is an affordable alternative with good results in the cost-effectiveness analysis—both immediately, and after two weeks of treatment—compared to sham dry needling in persons with chronic stroke.
Is Circulating DNA and Tumor Cells in Myeloma the Way Forward?
Authors: Arnault Carneiro Emilie , Barahona Filipa , Pestana Carolina , João Cristina
Published: January 2022

Multiple myeloma (MM) is the second deadliest hematological cancer. Despite the enormous innovation on MM treatment in the last decades, still 48% of patients die within 5 years after diagnosis. MM diagnosis and therapeutic strategy mainly rely on direct bone marrow (BM) assessment. Given the MM heterogeneity, BM biopsies do not accurately reflect the whole disease status, hampering accurate disease prognosis. Moreover, biopsies are painful and invasive procedures, highlighting the need for non-invasive and more accurate source of biomarkers. Liquid biopsies are promising sources of biomarkers that may overcome these limitations. Peripheral blood carries circulating myeloma components that are being extensively explored since the last few years as an alternative to BM aspirates. These include circulating tumor cells (CTC), cell-free DNA (cfDNA), and extracellular vesicles containing miRNA and proteins. The current review summarizes scientific evidence establishing BM as a gold standard for the diagnosis, prognosis, and evaluation of minimal residual disease. We discuss the last advances regarding cfDNA and CTC biomarkers from peripheral blood in patients with MM as well as the statistical validations. This paper addresses the technological hurdles associated with liquid biopsies and examines the missing steps for their inclusion into the clinical practice.
BrPARP1, a Poly (ADP-Ribose) Polymerase Gene, Is Involved in Root Development in Brassica rapa under Drought Stress
Authors: Cao Gangqiang , Jiang Wenjing , Shi Gongyao , Tian Zhaoran , Shang Jingjing , Xie Zhengqing , Chen Weiwei , Tian Baoming , Wei Xiaochun , Wei Fang , Gu Huihui
Published: January 2022

PARP proteins are highly conserved homologs among the eukaryotic poly (ADP-ribose) polymerases. After activation, ADP-ribose polymers are synthesized on a series of ribozymes that use NAD+ as a substrate. PARPs participate in the regulation of various important biological processes, such as plant growth, development, and stress response. In this study, we characterized the homologue of PARP1 in B. rapa using RNA interference (RNAi) to reveal the underlying mechanism responding to drought stress. Bioinformatics and expression pattern analyses demonstrated that two copy numbers of PARP1 genes (BrPARP1.A03 and BrPARP1.A05) in B. rapa following a whole-genome triplication (WGT) event were retained compared with Arabidopsis, but only BrPARP1.A03 was predominantly transcribed in plant roots. Silencing of BrPARP1 could markedly promote root growth and development, probably via regulating cell division, and the transgenic Brassica lines showed more tolerance under drought treatment, accompanied with substantial alterations including accumulated proline contents, significantly reduced malondialdehyde, and increased antioxidative enzyme activity. In addition, the findings showed that the expression of stress-responsive genes, as well as reactive oxygen species (ROS)-scavenging related genes, was largely reinforced in the transgenic lines under drought stress. In general, these results indicated that BrPARP1 likely responds to drought stress by regulating root growth and the expression of stress-related genes to cope with adverse conditions in B. rapa.
Physiological and Qualitative Response of Cucurbita pepo L. to Salicylic Acid under Controlled Water Stress Conditions
Authors: Biareh Vahideh , Shekari Farid , Sayfzadeh Saeed , Zakerin Hamidreza , Hadidi Esmaeil , Beltrão José Gil Teixeira , Mastinu Andrea
Published: January 2022

Limited water stress is one of the most important environmental stresses that affect the growth, quantity and quality of agronomic crops. This study was undertaken to investigate the effect of foliar applied salicylic acid (SA) on physiological responses, antioxidant enzymes and qualitative traits of Cucurbita pepo L. Plants exposed to water-stressed conditions in two years of field studies. Irrigation regimes at three soil matric potential levels (−0.3, −1.2 and −1.8 MPa) and SA at four levels (0.0, 0.5, 1.0 and 1.5 mg/L) were considered as main plot and sub-plots, respectively. The soil matric potential values (MPa) was measured just before irrigation. Results showed that under water stressed conditions alone, the amounts of malondialdehyde (MDA), hydrogen peroxide (H2O2) and ion leakage were higher compared with control treatment. However, spraying of SA under both water stress and non-stress conditions reduced the values of the above parameters. Water stress increased CAT, APX and GR enzymes activity. However foliar application of SA led to the decrease of CAT, APX and GR under all soil matric potential levels. The amount of carbohydrates and fatty acids increased with the intensity of water stress and SA modulated this response. By increasing SA concentration both in optimum and stress conditions, saturated fatty acids content decreased. According to our data, the SA application is an effective approach to improve pumpkin growth under water stress conditions.
Physical Activity Behaviors and Physical Work Capacity in University Students during the COVID-19 Pandemic
Authors: Bielec Grzegorz , Omelan Aneta
Published: January 2022

Objective. The COVID-19 pandemic led to restricted access to sports and recreation facilities, resulting in a general decrease in physical activity. Many studies present the results of on-line questionnaires conducted during the pandemic, but there are few reports of objectively measured indicators of physical condition. Thus, the objective of this study was to assess the changes in physical work capacity, body composition, and physical activity behaviors in university students during 14 weeks of lockdown. Material and Methods. Twenty students of Tourism and Recreation (13 female and 7 male) participated in the study. The first examination was conducted in November 2020, and the second in March 2021. Body composition was assessed with a Tanita 418 MA device. The students performed the PWC 170 cycling test and completed the International Physical Activity Questionnaire (short version) on-line. Results. Neither physical work capacity nor body composition parameters changed substantially during the analyzed period. In the female students, vigorous physical activity decreased significantly, but no substantial changes occurred in weekly metabolic equivalent of task. In male students, walking days and metabolic equivalent of task decreased, but the changes were not significant. Conclusions. Fourteen weeks of COVID-19 lockdown had little effect on the body composition, physical work capacity level, and physical activity habits of Tourism and Recreation students. Studies with larger groups of participants should verify the current conclusions, and care should be taken when extrapolating to other populations.
E-Cigarettes Use Behaviors in Japan: An Online Survey
Authors: Koyama Shihoko , Tabuchi Takahiro , Miyashiro Isao
Published: January 2022

Electronic cigarette (e-cigarette) use has become increasingly widespread throughout the world, including in Japan. However, little is known about how e-cigarettes are used in Japan, a country with heavy restrictions on nicotine-containing e-liquids and/or vaping products. This study examined e-cigarette use (e-cigarette use duration, frequency of use, device type, electrical resistance, nicotine use, favorite e-liquid flavors) among users in Japan, through an online survey using a web-based self-reported questionnaire which included questions about sex, age, combustible cigarette and heated tobacco product (HTP) use behaviors. Of 4689 e-cigarettes users analyzed, 93.5% were men and 52.9% had been using e-cigarettes for 1–3 years. Over 80% used e-cigarettes every day; 62.3% used nicotine liquid, and half of the nicotine liquid users used nicotine salt. The most popular liquid flavor was fruit (prevalence: 68.1%), followed by tobacco (prevalence: 48.4%). While 50.9% were e-cigarette single users, 35.2% were dual users (e-cigarettes and cigarettes or HTPs) and 13.8% were triple user (e-cigarettes, cigarettes and HTPs). This is the first comprehensive survey of Japanese e-cigarette users and our finding suggest more than half use nicotine liquid, although e-cigarettes containing nicotine liquid have been prohibited by the Pharmaceutical Affairs Act since 2010 in Japan. The study also showed 49.1% of participants used cigarettes and/or HTPs concurrently (dual or triple users).