bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Women in Raising Local Chicken on a Household Scale in Minahasa Regency, North Sulawesi: Review
Authors: Silondae Hasrianti , Muzayyanah M.A.U. , Sulastri Endang , Guntoro Budi
Published: November 2022

Local chicken is a source of animal protein that is needed by families in Indonesia. In the countryside, local chickens are very close to women's lives. This paper aims to determine the form of women's contribution to local chicken farms so that they can support the development of local chickens in Minahasa Regency as a local chicken producing district in North Sulawesi. As housewives, they do household chores such as cooking, cleaning the house, taking care of their husbands and children, and other household chores. Therefore, this paper examines the information obtained from various previous research literatures in the last ten years (2012-2021). Regarding the contribution of women in local chicken agribusiness that can increase family income and increase their role as housewives in Minahasa Regency, North Sulawesi. The contribution of women in local chicken farming in Minahasa district needs to be increased through counseling and training, and government programs and support are needed to empower women to be involved in local chicken production and marketing. This contribution strengthens the position of women in making decisions to prepare animal protein foods in the household. Family welfare can be realized by the role of women in chicken agribusiness.
Acceleration of smallholder plantation development through the development of farmers economic institutions in North Sulawesi
Authors: Hutapea Ronald , Tulalo Meity A. , Elizabeth Roosganda , Kindangen Jantje G.
Published: November 2022

The agricultural sector in North Sulawesi is about 50-60% of smallholder plantation areas with an area of 413,000 ha, and approximately 97% of its managers are farmers located in one area. There are nine plantation crops that are generally managed by independent farmers with an average land ownership of 1.2 ha/family farmers. Farm management of each commodity is more dominant conventionally and monoculture. The financial value per unit of farming of various commodities is still low due to several factors, such as sales transactions and the acquisition of production equipment is still carried out individually. Based on the above background, an analysis of the acceleration of smallholder plantation development is carried out through the development of farmer economic institutions in North Sulawesi. This paper aims to see the importance of building a developed and independent farmer economic institution for the acceleration of smallholder plantation development. The data used is secondary data and the results of the research were analyzed descriptively qualitatively. The result of this study show that a developed and independent farmer economic institution in each village will greatly help farmers to guarantee the development of commercial farming and farmers income more adequately.
Opportunities for the Development of The Oleochemical Industry of Coconut Products
Authors: Joseph Gabriel H. , Kindangen Jantje G. , Paat Paulus C. , Taulaby Darwin
Published: November 2022

Coconut commodities that have been processed into copra or oil are less strategic to develop because they compete with palm oil and other vegetable oils such as soybean oil, sunflower nuts. As a result, the price of coconut oil, although the upward trend, but fluctuates greatly. To minimize the effects of price fluctuations, it is necessary to diversify utilization and processing. In addition to being edible oil, coconut oil can be further processed into oleochemical products. Important oleochemical products are fatty acids, fatty acid methyl esters, fatty acid alcohols, and glycerin. A possible problem is competition with Asia Pacific countries that are also developing the oleochemical industry. This paper aims to present technological introductions of some high economic value oleochemical products such as fatty acids, fatty acid methyl esters, fatty acid alcohols, and glycerin. Systematic writing approach in the form of a review based on literacy as a secondary data source. The oleochemical industry entering the industry 4.0 era is quite prospective to be developed in Indonesia to achieve the optimal economic value of coconuts in terms of availability of raw materials and technological innovation, technical excellence, employment, and domestic and foreign market opportunities.
Strategy for Developing Organic Rice Farming in Sleman Regency, Special Region of Yogyakarta
Authors: Istiyanti Eni , Widowati Indah , Triyono  , Angger Trisnanti Novia
Published: November 2022

Sleman Regency is a centre for organic agriculture development in the Special Region of Yogyakarta, as evidenced by the large number of farmer groups that have received organic certification. Sayegan is one of the districts in Sleman Regency that is developing organic rice although it is still in the transition stage from conventional to organic rice, namely semi-organic rice. The research objective is to determine the strategy used for developing organic rice farming. The sample in this study consisted of 12 key persons, namely the Head of the Technical Implementation Unit (UPT), Field Agricultural Extension Officer (PPL), the Officer for Controlling Plant Pest Organisms (POPT), 4 heads of farmer groups, and 5 farmers who own land of 1 hectare. The research was conducted by survey in Sayegan District. The analysis technique uses Analysis Hierarchy Process (AHP). The results showed that the strategy for developing organic rice farming in Sleman Regency consisted of (1) the provision of production facilities of good quality on time and in the right amount, (2) encouraging farmers to use labelled superior seeds, and (3) increased motivation, knowledge, and skills of organic rice cultivation.
The Application of TURIMAN JAGOLE Technological Innovation to Increase Crop Index and Urban Farmer Income in DKI Jakarta
Authors: Zulkarnaen Iskandar , Irawati Ana Feronika Cindra , Ali Asep , Sutardi Susi , Amatillah Chery Soraya , Sugiartini Emi
Published: November 2022

The study aims to determine the effect of applying for intercropping food crops (rice, corn, and soybeans = jagole) on the cropping index and income of urban farming community activists. This study was conducted by comparing the use of six models of growing food crops, namely three kinds of monoculture model of jagole, upland rice-soybean, sweet corn-soybean, and sweet corn-upland rice polyculture/ “Turiman”. Observational data includes data on land characteristics, annual cropping patterns in related locations, and input-output data of the test models. Corn and soybeans are harvested young. Data were processed using descriptive analysis and the economic feasibility analysis of the tested technology was based on the R/C ratio. Based on data, it is known that there is potential to increase the cropping index of dry or limited land in the Jakarta area, from 1-2 to 2-3 a year by optimizing planting through intercropping systems/ food crop Turiman. such as corn-upland rice-soybean. The results of the analysis showed that the soybean monoculture technology model, with yields of young soybeans, gave a higher profit (R/C 2.58), compared to the other models, namely sweet corn monoculture, upland rice monoculture, upland rice-sweet corn polyculture, soybean-sweet corn polyculture, soybean-upland rice polyculture, and (R/C respectively: 0.24, 0.54, 0.17, 1.25, and 1.71).
Farmers' Interest in Continuing Organic Rice Farming in Yogyakarta
Authors: Triyono  , Kurniawati Khairunnisa
Published: November 2022

The study aims to determine the interests of farmers and the factors that influence farmers' interest in continuing organic rice farming in Sleman Regency. The study conducted in Sleman Regency, which is an area that has applied the principles of organic rice farming by taking about 70 organic farmers. The data was analyzed descriptively and multiple regression analysis. The results showed (1) The interest of farmers to continue organic rice farming based on internal needs and emotional are verry powerful, while social motives are included in the strong category. It is known that the interest of farmers in continuing organic rice farming in Sleman Regency is said to be very high in meeting physical and spiritual needs, high in social relations, and very high in paying attention to organic rice. (2) Factors that influence the overall interest of farmers in terms of internal needs, social motives, and emotions are age, formal education, non-formal education, farming experience, income, land area, frequency of presence of extension workers, assistance, and number of dependents.
Effect of Irrigation System on Production and Profit in Red Chili Farming on Rice Land, Kretek District, Bantul Regency
Authors: Risvansuna Fivintari Francy , Darmayanti Anggie
Published: November 2022

The purposes of this research are to determine the factors that affect the costs, income, income, and profits of red chili farming on rice land in Bantul Regency. Determination of respondents using a random sampling method with 45 samples of farmers and the census method with 15 samples of farmers. Data were obtained through interviews using the help of a questionnaire. Then the data were analyzed using multiple linear regression analysis, production costs, revenues, revenues, and profits. The results showed that the production factors that significantly influenced the production of red chili were land area, labor, manure and type of irrigation technology. The production costs incurred on an area of 3,500 m2 are IDR. 13,674,700 for manual irrigation and IDR. 10,214,518 in the shower irrigation area. The income obtained by red chili farmers is IDR. 21,345,619 for manual irrigation and IDR. 20,252,666 for shower irrigation. The income received by farmers is IDR. 12,643,8182 for manual irrigation and IDR. 12,770,400 in shower irrigation. The profit obtained by the farmer is IDR. 7,670,919 for manual irrigation and IDR. 10,038,148 shower irrigation.
Technology for salt brines utilization on distant pastures in the arid zone of the Republic of Kazakhstan
Authors: Bezborodov Yuri , Balgabaev Nurlan , Khozhanov Nyetbai , Ustabaev Timur
Published: November 2022

The aim of the research is to develop technology for integrated treatment of surface, underground and mineralized waters, collected by drainage network contaminated by pollutants, to produce both water of the required quality and saturated brines. During experiments the main task was to select and reveal the optimum mode of desalination of initially mineralized ground water belonging to a certain type. The operation mode of reverse osmosis system was selected by gradual change of pressure and change of permeate and concentrate volume ratio (%), parameters of desalination regime change (flow rate, pressure, salt output) were recorded in time. The research was conducted in Zhambyl region, located in the southern part of the Republic of Kazakhstan in 2021. Each operation stage of changing desalination regime lasted for 50 hours, while non-stop work being performed. The tests of reverse osmosis system with natural ground waters of sulphate-chloride-sodium and sulphate-carbonate-sodium types revealed quite reliable and stable desalination regime under changing flow discharge and permeate and concentrate volumes ratios and multiple initial water concentrations. Application of the proposed technological scheme will allow providing the good quality drinking water for shepherd brigades on summer distant pastures and further utilization of salt brines (concentrated waste waters, remained after desalination) in a safe for the environment manner.
Green behavior activism through rural-based community development
Authors: Hilmi Pujihartati Sri , Dwi Astuti Nurhaeni Ismi , Tri Kartono Drajat , Demartoto Argyo
Published: November 2022

Environmental problems are often seen as a major challenge for urban communities. Social movements aimed at improving the quality of the environment are mostly carried out by urban communities who are worried and aware of their environmental conditions. This is contrasts with rural communities who are often seen as environmentally passive on environmental threat. However, this does not mean that rural communities are passive, calm, and even indifferent to promoting environmental issues. Rural communities currently need to increase environmental awareness when the spread of non-green behavior that comes from urban culture. This paper explores the green behavior activism carried out by rural community in the Pulosari, Located in Karanganyar district. The case study method is used in this study. The research conducted in 2021 -2022. Data was gathered through observation, in-depth interviews, and a review of the literature. The population is the Company management as CSR Provider, the community as the participant of the community development. The result is this activism could be a Preventive measures and early awareness of environmental issues. This activism can be a model for others to develop green behavior in the midst of the non-green behavior that mostly come from consumptive urban community.
The role of local government developing participatory learning methods in empowering small farmers
Authors: Aminah Sitti
Published: November 2022

Farmers learning process have not increased their awareness to understand their own problems, potentials, and opportunities. The study aimed to analyze participatory learning methods in the implementation of smallholder farmer empowerment programs. The study was designed as a quantitative method by survey methods, and the analysis technique used descriptive statistics. The study results showed that the government's capacity to develop the participatory learning method in small farmer empowerment program was in the low category. The participatory learning method's four indicators including, communication intensity, equality source, dialogical application, and learning material appropriate were in the low category, while the communication method is in the high category. Therefore, the government needs to encourage participatory learning methods in small farmer empowerment programs through some strategies including, increasing the intensity of communication, developing equality and dialogue, adjusting learning materials according to farmers' needs, and developing appropriate learning methods.
Realizing the Community Participation of Batik Craftsmen in Sustainable Development in Tampo Village, Banyuwangi Regency
Authors: Istiqomah Ni'matul , Irwansyah M. Rudi , Hadi Mustofa Rochman , Rokhmani Lisa , Maulidianto Rizqi
Published: November 2022

The development of a village can be built with the role of government and community participation. Tampo Village, Banyuwangi Regency is one of the villages with the potential for famous Banyuwangi batik craftsmen. Community participation is one of the capitals for a village to improve its economic development of a village. Sustainable development is one of the elements that encourage village development. This study uses descriptive qualitative research methods, namely analyzing qualitative data to explain how to build community participation in realizing sustainable development in Tampo Village with Potential as a Batik Tourism Village. Data collection was done by field observations, in-depth interviews, and documentation. As one of the possible villages, the role of community participation has not been implemented properly. The existence of the association has not helped the development of the village so much. Therefore, it is necessary to strengthen how to build a community of batik craftsmen as a form of community participation. requires local government and community support to realize sustainable development in Tampo Village, Banyuwangi Regency.
A Tourism Village Development Model Based on Cultural Ecology on the Slopes of Mount Lawu, Indonesia
Authors: Wibowo Agung , Suwarto  , Sugihardjo
Published: November 2022

Sustainable development has emerged in response to the environmental damage caused by exploitative development, and this has led to the need for efforts to align development with environmental preservation. There are concerns that the rapid rise in tourism village development will destroy the ecological balance. Several models for tourism village development have emerged, in line with the capacity of human resources and local potential. This research aims to investigate a development model for mountainside tourism villages based on an ecological perspective. A qualitative research method is used with a phenomenological approach. The research location is the tourism villages on the slopes of Mount Lawu, Magetan Regency in East Java, Indonesia. The research results show that a tourism village development model based on cultural ecology, marked by the development of social networks and local cultural potential, has been proven to empower the local communities.
Food yard program in urban and rural areas of South Kalimantan
Authors: Qomariah Retna , Lesmayati Susi , Susilawati  , Awanis
Published: November 2022

The participation of community groups that receive P2L programs affects the success of the program. The research aims to find out: 1) The participation level of rural and urban communities in the P2L at South Kalimantan. 2) The differences in the participation level communities in P2L. 3) The factor that affected the community participation in P2L. Determination of respondents through simple random sampling based on Krejcie and Morgan's table. The data were analyzed descriptively using Mann Whitney Wilcoxon to determine the difference in the participation level of the communities and Spearman rank correlation to determine factors related to community participation. This research showed that 1) The participation level of communities in the P2L program was in the high category. 2) The score of community groups' participation in rural areas was higher than in urban areas, but there is no significant difference between participation in those communities. 3) Factors related to the participation of community groups in the P2L in community areas were education level, knowledge and skills of plant cultivation, family food sources, size of the home yard, family income, and risk-taking activities. In contrast, the factor of understanding the P2L only related to community participation in urban areas.
Growth and yield response of rice based on different planting distances in rainfed field
Authors: Dyah Arianti Forita , Nurwahyuni Endah , Minarsih Sri , Faizal Amri Aldicky
Published: November 2022

Planting distance is one of the important aspects in cultivation management. The study aimed to determine the response of rice plants at various planting distance based on the components of growth and yield. It was conducted in a rainfed rice field covering an area of approximately 1 ha during the Second Planting Season in Pemalang Regency used a Randomized Block Design (RBD) using planting distances as a single factor, which consisted of Jajar legowo 2: 1/40 (12.5 cm x 25 cm x 40 cm); 2: 1/50 (15 cm x 25 cm x 50 cm) and conventional planting distance/Tegel spacing system (20 cm x 20 cm), repeated five times. The observed variables include growth and yield components. Data were analyzed by means of variance (Anova) followed by the Least Significant Difference (LSD) test. The results of the study showed that the Jajar legowo 2: 1/40 planting system was observed to be able to produce the highest number of tillers, even though the Jajar legowo 2: 1/50 resulted in the highest plant height, number of full grains, and produced the highest HDG of 5,619 tons ha-1compared to other planting distances.
Response of sorghum variety growth in the first ratoon with liquid organic fertilizer application
Authors: Nurmala Sari Eka , Harsono Puji , Supriyono
Published: November 2022

The advantages of ratoon system are short harvesting time, minimum irrigation needed, and lower farming cost compared with the first plant of seed. Liquid organic fertilizer (LOF) application is selected to increase nutrition absorption and as an attempt of supporting sustainable agriculture program. The objective of research is to study the effect of first-ratoon sorghum variety and LOF dose on sorghum growth. This research used completely randomized block design factorial. The first factor is sorghum variety consisting of Numbu, Kawali, and Suri 3. The second treatment of LOF dose consisted of 0 L.ha-1, 3 L.ha-1, 6 L.ha-1, and 9 L.ha-1. Data analysis was conducted variance analysis of 5% followed with least significant different test 5% and polynomial regression test. The result of research shows that Numbu with the optimum dose of LOF 3,8 L.ha-1 produced the highest leaf area and LAI of 2570 cm2 and 2,56 compared to other varieties. Suri 3 and Numbu yield higher fresh stove weight than Kawali. This means that Numbu and Suri 3 can be used as a source of animal feed.
Identification of Dryland Local Rice Varieties and Their Advantages Based on Agronomic Characters
Authors: Yustisia  , Atekan  , Karman Joni , Irsan Fuadi , Suryana Yayan , Eliza Maryana Yeni , Juwita Yuana , Riyanto Damasus , Heryanto R. Bambang , Khodijah Siti
Published: November 2022

The information on rice genetic material is needed to create new high-yielding varieties adaptive to dryland. Local rice genetic resources have been tested to be tolerant under conditions affected by global climate change (increased temperature, pest/disease attacks, droughts). This study aims to identify and characterize the agronomic character of local rice in Musi Rawas (MURA) and North MURA Regencies, South Sumatra. The results of identification and characterization, as well as correlation and regression analysis, revealed that three local varieties have agronomic characteristics that determine high-yield local rice productivity. This information can be utilized by breeders to create new superior varieties of rice in dryland. The agronomic characteristics of three local rice varieties that determine productivity are the area of the flag leaf and the number of filled grain/panicles. Local varieties with superior agronomic characteristics are Siam, Bolouh, and Gel. These three varieties have the potential to be used as parents in the creation of new high-yielding varieties that are specific, namely having broad flag leaves and a high number of filled grains/panicles. The acquisition of new high-yielding varieties specific to dryland through a breeding program will increase the choice of varieties for stakeholders and support increased rice production in dryland.
Technology package of land preparation with solarization and biofertilizer on chili
Authors: Ratna Purnamasari Neneng , Dianawati Meksy
Published: November 2022

Intensive land use without regard to soil fertility and health can reduce crop productivity. The purpose of this research was to compare yields of various packages of land preparation technology that can support soil fertility and health. The study was conducted in Cianjur Regency, West Java, Indonesia from June until November 2019. The study used a randomized block design with four treatments and six replications. The technology packages tested were the solarization of mulch installation, the use of biofertilizers, and chemical fumigation. Data were analysed by analysis of variance and followed by Duncan's test at the 95% confidence level. The results showed that there was no difference in fruit weight and number of fruits per plant, as well as weight per fruit in all treatments. However, the treatment of delaying planting for two weeks after mulch installation and the use of biofertilizer has the potential to be studied further because they were significant at several harvests. The weight per plant was 30.34-46.67 g higher than other treatments at the 4th harvest, the number of fruits was 3.2-11.67 higher at the 3-4th harvest, and the weight per fruit was 0.31-0.65 higher in the 2nd-5th harvest.
Consumer preference level of fried shallots from several varieties
Authors: Lintang Meivie , Layuk Payung , Tandi Olvie , Salamba Herlina
Published: November 2022

Fried shallot is one of the most tasteful products that is normally used as a condiment for appetites such as noodles, fried chicken, and sticky rice. The study aimed to analyze the level of consumer preference for fried shallots from local varieties of Lansuna, Tajuk, Batu Ijo, and Bima Brebes by using additional ingredients of tapioca flour and CaCl2. An organoleptic test was carried out on 24 panelists on 12 samples of fried shallots treatment. Data collected were analyzed using a scoring system and anova statistical analysis. The result showed that there is a diversity of panelists' preferences of fried shallot from slightly like to very like in Panelist perceptions, with the highest percentage value being Batu Ijo with CaCl2 for the color parameter (62.5%), Bima Brebes with tapioca flour for the flavor parameter (50%), and in Lansuna with tapioca flour for texture and taste parameters (50%). The addition of tapioca flour can increase the level of panelist acceptance of the texture and taste of 4 varieties of fried shallots, compared to the use of CaCl2 and without the use of additional ingredients.
Use of Seaweed Liquid Extract and Cow Urine for Lettuce Growth in Hydroponic System
Authors: Muhammad Harjoni Kilowasid Laode , Fadhillah Arsani Sitti , Corina Rakian Tresjia , Hasid Rachmawati , Siti Anima Hisein Waode , Nurmas Andi
Published: November 2022

Lettuce cultivated by millennial farmers using a hydroponic system in urban areas. Seaweed extracts and cow urine contain nutrients and plant growth regulators. This study aims to determine the effect of a formulation containing inorganic nutrient solution, seaweed liquid extract, and mixed cow urine on lettuce growth, as well as the volume of commercial nutrient mixture that can be substituted by these additives in a hydroponic system. The treatment used contains a combination of inorganic fertilizer solution (CF), seaweed liquid extract (SLE), and cow urine (CU). Every repeated three times in a randomized block design. Results, the nutrient mixture had a significant effect on the height, leaves number as well as wet and dry weight of the plants. Lettuce planted on 50% CF+ 25% SLE+ 25% CU was the tallest when observed on days 7, 14, and 42 after planting. The highest fresh and dry weight was also obtained from this nutrient formulation. On day 35, the highest leaves number was recorded from plants on the 100% CF+ 0% SLE+0% CU medium. Concluded, a mixture of seaweed liquid extract and cow urine has the potential to reduce the inorganic fertilizers use as a nutrient solution in a hydroponic system.
Testing subjective well-being predictors for adolescents
Authors: Özbiler Şerife , Ağan Hasan
Published: November 2022

The aim of this study is to test the predictive roles of Turkishspeaking adolescents’ health promotion behaviours and resilience levels on their subjective well-being. We also test the mediating role of adolescents’ resilience. A total of 502 (228 male, 274 female) Turkish-speaking adolescents who aged between 14 and 18 participated in this study in the northern part of Cyprus. Data were collected by using the Sociodemographic Information Form, the Adolescent Health Promotion Scale, the Child and Youth Psychological Resilience Measure-12, and the Adolescent Subjective Well-Being Scale. To test two competing structures (health promotion behaviours and resilience) for explaining the subjective well-being of adolescents, covariance-based structural equation modeling was applied using SPSS AMOS 24. The results showed that adolescents’ health promotion behaviours and resilience significantly predicted their subjective well-being. In other words, both adolescents’ health promotion behaviours and resilience are important triggers for subjective well-being. Also, resilience partly mediates the relationship between health promotion behaviours and subjective well-being. The findings suggest that in order to promote the subjective well-being of adolescents, health promotion behaviours and resilience are essential.
Traces of Cyprus culture in contemporary Cyprus Turkish poetry
Authors: Öznur Şevket , Uçar Ahmet
Published: November 2022

The parallelism between language and culture emerges as a reality accepted by everyone. The individual living in a certain society carries the cultural elements of the society in his own life. The poet, who is in the society in question, reflects the cultural characteristics of the society to his poetry through language. When we look at the formation of Cypriot identity in Turkish Cypriot poetry, it appears as a result of the movement initiated against Turkish nationalism by the 1974 Generation or the Red Belt. In the poems of Fikret Demirağ, Feriha Altıok, Fatma Akilhoca, Saygın Akanyeti, Gür Genç (Gürgenç Korkmazel), Tamer Öncül, M. Kansu, Osman Türkay, Altay Burağan, Orbay Deliceırmak and Faize Özdemirciler, which are considered to have begun in 1943, Contemporary Turkish Cypriot poetry is included. There are many elements to Cypriot culture. In this study, many determinations about the Cypriot dialect, Cypriot life, Cypriot plants and Cypriot food and beverage culture are presented in the poetry books of the above-mentioned poets.
Characterization of Shear Stress Mediated Platelet Dysfunction: Data from an Ex Vivo Model for Extracorporeal Circulation and a Prospective Clinical Study
Authors: Hidiatov Oleg , Gaupp Alisha , Marini Irene , Pelzl Lisann , Wagner Miriam , Rigoni Flavianna , Witzemann Andreas , Häberle Helene , Martus Peter , Ngamsri Kristian-Christos , Konrad Franziska M. , Rosenberger Peter , Straub Andreas , Bakchoul Tamam , Althaus Karina
Published: November 2022

Extracorporeal circulation (ECC) is frequently used in intensive care patients with impaired lung or cardiac function. Despite being a life-saving therapeutic option, ECC is associated with increased risk for both bleeding and thrombosis. The management of bleeding and thromboembolic events in ECC patients is still challenging partly due to the lack of information on the pathophysiological changes in hemostasis and platelet function during the procedure. Using a combination of an ex vivo model for shear stress and a sensitive and easy-to-use laboratory method, we analyzed platelet responsiveness during ECC. After shear stress simulation in an ex vivo closed-loop ECC model, we found a significantly decreased response of α-granules after activation with adenosine diphosphate and thrombin receptor activating peptide (TRAP-6) and CD63 expression after activation with TRAP-6. Mepacrine uptake was also significantly reduced in the ex vivo shear stress model.

In the same line, platelets from patients under ECC with venovenous systems and venoarterial systems showed impaired CD62P degranulation after stimulation with ADP and TRAP-6 compared with healthy control on day 1, 6, and 10 after implantation of ECC. However, no correlation between platelet degranulation and the occurrence of bleeding or thromboembolic events was observed.

The used whole blood flow cytometry with immediate fixation after drawing introduces a sensitive and easy-to-use method to determine platelet activation status and our data confirm that increased shear stress conditions under ECC can cause impaired degranulation of platelet.
Association between Platelet Count and Treatment Effect of Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes
Authors: Koch Tobias , Lahu Shqipdona , Coughlan J. J. , Cassese Salvatore , Voll Felix , Ndrepepa Gjin , Menichelli Maurizio , Valina Christian , Hemetsberger Rayyan , Witzenbichler Bernhard , Bernlochner Isabell , Joner Michael , Xhepa Erion , Mayer Katharina , Kessler Thorsten , Laugwitz Karl-Ludwig , Richardt Gert , Schunkert Heribert , Angiolillo Dominick J. , Sibbing Dirk , Kastrati Adnan , Kufner Sebastian
Published: November 2022

Background The relative efficacy and safety of ticagrelor and prasugrel based dual antiplatelet therapy strategies according to the platelet count (PC) in patients with acute coronary syndromes (ACS) have not been defined.

Methods This is a posthoc analysis of the ISAR-REACT 5 trial, in which patients presenting with ACS were randomized to treatment with ticagrelor versus prasugrel. Patients were divided into quartiles according to PC. The primary endpoint was incidence of death, myocardial infarction, or stroke, and the safety endpoint was incidence of BARC (Bleeding Academic Research Consortium) type 3 to 5 bleeding at 12 months.

Results A total of 3,943 patients with known PC (997 patients in quartile 1 (Q1), 1,003 in quartile 2 (Q2) [205 ± 10.3 × 109/L], 961 patients in quartile 3 (Q3) [241 ± 11.7 × 109/L], and 982 patients in quartile 4 (Q4) [317 ± 68.6 × 109/L]). There was no significant interaction between treatment arm (ticagrelor vs. prasugrel) and PC group with respect to primary endpoint (Q1: 8.8 vs. 6.3%, hazard ratio [HR] =1.41, 95% confidence interval [CI]: 0.89–2.23; p = 0.148; Q2: 9.9 vs. 5.8%, HR = 1.68, 95% CI: 1.06–2.66; p = 0.027; Q3: 7.8 vs. 5.5%, HR = 1.43, 95% CI: 0.87–2.37; p = 0.159; Q4: 10.1 vs. 10.1%, HR = 1.05, 95% CI: 0.71–1.57; p = 0.799; p for interaction [p
int] = 0.482) and with respect to bleeding endpoint (Q1: 5.8 vs. 4.2%, HR = 1.41, 95% CI: 0.76–2.63; p = 0.279; Q2: 6.4 vs. 3.7%, HR = 1.62, 95% CI: 0.85–2.06; p = 0.140; Q3: 4.4 vs. 3.0%, HR = 1.53, 95% CI: 0.73–3.18; p = 0.258; Q4: 5.6 vs. 8.5%, HR = 0.67, 95% CI: 0.40–1.14; p = 0.138, p
int = 0.102).

Conclusions In this analysis, incidences of ischemic and bleeding events at 12 months are comparable across quartiles of platelet count.
Attitude of the Dental Undergraduate Students and Interns towards Dentistry Post COVID-19
Authors: Bhat Supriya , Gadiyar Akshatha
Published: November 2022

Introduction The period of coronavirus disease 19 (COVID-19) is a significant period from various aspects such as world health and socioeconomic considerations. The majority of the hospitals involved in dental education had previously limited their clinical practices to dental emergencies, but now are geared up for nonemergent conditions. As teaching modalities shifted to online platforms, students have reported to be anxious with regard to accomplishment of required clinical skills, patient care, and forthcoming graduation. Fresh graduates have reported a delay in the drive, which they would have been able to achieve in the initial stages of their profession.

Objectives To assess the attitude of the dental undergraduate students and interns toward dentistry post-COVID-19.

Results The majority (80.2%) were prepared for the challenges lying ahead before beginning to work on patients. Also, 16% were willing to treat patients, 28% did not want to treat patients, while 44% were willing to handle emergency cases. Next, 67.8% were scared of infecting themselves while administering dental treatment and 78.9% were concerned that there could be more such pandemics. In total, 21.6% of the respondents who wished that they chose an alternate profession whereas 70.5% of participants felt that the scope of dentistry has not diminished. Also, 90.7% were interested to pursue postgraduation, and 86.3% felt that this was a passing phase and things would be normalized soon.

Conclusion With second and third waves being rampant, novel coronavirus has become a public health crisis. Because dental services cannot be stopped for a long time, it is essential for dental students to be well trained to limit the spread of the disease. Owing to the present scenario, appropriate donning and doffing of PPE (personal protective equipment) is a pivotal step in direct patient care, and simulation-based training may help ensure that these skills are acquired by them.
Giant Sternal Pilomatricoma: An Unusual Tumor at an Uncommon Site
Authors: Shetty Abhijith Sudhakar , HL Kishan Prasad , Asnani Ritu
Published: November 2022

Pilomatricoma, pilomatrixoma, or calcified epithelioma of Malherbe is an uncommon, benign, isolated tumor of hair matrix primarily seen in children and young adults. The most common location is the head and neck region. It usually manifests as a small nodular mass. Here we report a rare case of giant pilomatricoma over the sternum in a 60-year-old male patient with an unusual clinical and radiological presentation mimicking a calcified sebaceous cyst.
Cutting-Edge Developments in Oncology Research
Authors: Datta Neelabh
Published: November 2022

The field of oncology research has made many successful advances, and new discoveries have started making headlines. As an example, the identification of immune checkpoint inhibition mechanisms in carcinogenic cells led to the development of immunoassays, which have helped many cancer convalescents recover. This article covers the most advanced cutting-edge areas of cancer research: exosomes, microbiomes, immunotherapy, nanocarriers, and organoids. Research on exosomes advances cancer detection and treatment modalities, as well as further understanding of mechanisms that regulate carcinogen cell division, proliferation, invasion, and metastasis. Microbiome consents the researchers to understand the disease cancer. Immunotherapy is the third method in the treatment of cancer. Organoid biology will be further expanded with the aim of translating research into customized therapeutic therapies. Nanocarriers enable cancer specific drug delivery by inherent unreceptive targeting phenomena and implemented active targeting strategies. These areas of research may also bring about the advent of the latest cancer treatments in the future. Malignant infections are one of the leading grounds for demise in the society. Patients are treated with surgery, radiation, and chemotherapy. In chemotherapy, the malignant cells are destroyed and the tumor burden is reduced. However, in most cases, resistance to chemotherapy develops. Therefore, there is a constant need for new additional treatment modalities and chemotherapeutic complex rules. Due to the rapid development in cancer research, I can only mention a few goals and treatment options that I have chosen; However, this review specializes in new and admirable significant strategies and compounds.
Building eco-surplus culture among urban residents as a novel strategy to improve finance for conservation in protected areas
Authors: Nguyen Minh-Hoang , Jones Thomas E.
Published: November 2022

The rapidly declining biosphere integrity, representing one of the core planetary boundaries, is alarming. In particular, the global numbers of mammals, birds, fishes, and plants declined by 68% from 1970 to 2016. One of the most widely accepted measures to halt the rate of biodiversity loss is to maintain and expand protected areas that are effectively managed. However, doing so requires substantial finance derived from nature-based tourism, specifically visitors from urban areas. Using the Bayesian Mindsponge Framework (BMF) for conducting analysis on 535 Vietnamese urban residents, the current study examined how their biodiversity loss perceptions can affect their willingness to pay for the entrance fee and conservation in protected areas. We found that perceived environmental degradation, loss of economic growth, loss of nature-based recreation opportunities, and loss of knowledge as consequences of biodiversity loss indirectly affect the willingness to pay through the mediation of the attitude towards conservation. Notably, perceived knowledge loss also has a direct positive influence on the willingness to pay for the entrance fee and conservation. In contrast, perceived loss of health is negatively associated with the attitude towards conservation. Based on these findings, we suggest that building an eco-surplus culture among urban residents by stimulating their subjective cost-benefit judgments towards biodiversity loss can be a promising way to generate more finance from nature-based tourism for conservation in protected areas and ease the domestic government’s and international organizations’ funding allocation problems. Eco-surplus culture is a set of pro-environmental attitudes, values, beliefs, and behaviors shared by a group of people to reduce negative anthropogenic impacts on the environment and conserve and restore nature.
Roadmap for space-based quantum internet
Authors: Johnson-Groh Mara
Published: November 2022

A review of compact quantum entanglement sources provides an outlook for the future of quantum networks in space.
Degree adverbs in spoken Mandarin
Authors: Huang Pei-Wen , Chen Alvin Cheng-Hsien
Published: November 2022

Managing near-synonymous morphosyntactic constructions in language is often at the core of a speaker’s grammatical competence. This study investigates the usage patterns of four near-synonymous degree adverb constructions (i.e., hěn, tài, mán, and chāo) in the Taiwan Mandarin Corpus in TalkBank. After retrieving the concordance lines of these four constructions from the corpus, we manually annotated their co-occurring linguistic patterns/structures at multiple linguistic levels. In particular, we utilized a corpus-based behavioral profile approach to determine the interrelationship of the four constructions based on their distributional patterns and identified their distinctive behavioral patterns, producing a comprehensive delineation of their functional differences. Our analysis suggests that these four constructions fall into two super-clusters, i.e., chāo-mán and tài-hěn. Chāo and mán differ mainly in the pragmatic sentiments of their associated predicates, their co-occurrences with the nominalization structure, and their productivity in lexicalization. Tài and hěn differ mainly in their co-occurrences with the final particle -le, the semantic and pragmatic functions of their associated predicates, and the semantics of their associated head nouns. We have also connected these corpus-based distributional patterns to previous research findings, demonstrating the effectiveness and applicability of the behavioral profile approach for the analysis of near-synonymous morphosyntactic alternations in language.
democracy in Taiwanese presidential inaugural addresses
Authors: Hsu Hsiao-Ling , Lai Huei-ling , Liu Jyi-Shane
Published: November 2022

This study explored metaphorical expressions related to democracy in 15 Taiwanese presidential inaugural
addresses. The source domain concepts mapped to understand democracy were examined and the relationship between these
metaphorical expressions and ideologies was teased out by employing the discourse-historical approach. Our analysis demonstrates
that various source domain concepts were utilized to discuss democracy, and most newly-emerged types occurred after the
success of the first direct presidential election in 1996. A more detailed analysis of the source domain elements showed that
different scenarios were highlighted, reflecting specific ideologies embedded along with the social, historical and political
situation.
Universality? Cross-linguistic influence?
Authors: Chung Chi-ting Alvan , Chen Chun-yin Doris
Published: November 2022

The present study investigated the use of apology response (AR) strategies by L1-Chinese L2-English learners and L1-English L2-Chinese learners from a cross-linguistic perspective. A total of 18 Taiwanese college students who were learning English as a foreign language and 18 foreigners in Taiwan who were learning Chinese as a second language were recruited to complete an oral discourse completion task both in Chinese and English. The major findings are as follows: First, the two groups showed no significant difference in their choice of AR strategies, both favoring Acceptance and Minimization, two face-preserving types, to show politeness. Second, cross-linguistic influence was found to affect our participants’ AR performances. Both positive and negative influences occurred. Finally, regarding the use of multiple strategies, both groups of participants tended to combine Acceptance with other strategies to maintain social relationships. The results showed both language universal and language-specific features in the AR realizations in Chinese and English. The dominant use of positive response strategies, namely Acceptance and Minimization, highlights the profound influence of politeness principles.
On the use ofsì?(‘yes?’) as invariant follow-up in Italian
Authors: Viola Lorella
Published: November 2022

Follow-ups are elliptical interrogative forms typically constituting an utterance in their own right. They are used to signal attention to the interlocutor, to encourage them to continue or as a reply to a call. This paper investigates the invariant follow-upsì?(‘yes?’) in Italian and it argues that it represents a case of pragmatic language change. To this end, it investigates the diachronic distribution, collocation and contexts of usage ofsì?in a variety of language sources in relation to plausible, equivalent expressions (i.e.,dimmianddica[‘tell me’]). The analysis will show that since its earliest record of use in films in 1960, the frequency of occurrence of this form has dramatically increased to the point that, today, it is the preferred device. The study will also provide solid evidence of positive correlations between the use ofyes?in English language audio-visual products and the use ofsì?in scripted and real-use Italian, strongly suggesting that the marker would in fact be a case of pragmatic borrowing from English.
Early T-bet promotes LFA1 upregulation required for CD8+ effector and memory T cell development
Authors: Pritchard Gretchen Harms , Phan Anthony T. , Christian David A. , Blain Trevor J. , Fang Qun , Johnson John , Roy Nathan H. , Shallberg Lindsey , Kedl Ross M. , Hunter Christopher A.
Published: November 2022

The T-box transcription factor T-bet is regarded as a “master regulator” of CD4+ Th1 differentiation and IFN-γ production. However, in multiple models of infection, T-bet appears less critical for CD8+ T cell expansion and effector function. Here, we show that following vaccination with a replication-deficient strain of Toxoplasma gondii, CD8+ T cell expression of T-bet is required for optimal expansion of parasite-specific effector CD8+ T cells. Analysis of the early events associated with T cell activation reveals that the α chain of LFA1, CD11a, is a target of T-bet, and T-bet is necessary for CD8+ T cell upregulation of this integrin, which influences the initial priming of CD8+ effector T cells. We propose that the early expression of T-bet represents a T cell–intrinsic factor that optimizes T–DC interactions necessary to generate effector responses.
Multiconfiguration b-AsP-based doping systems with enriched elements (C and O): novel materials for spintronic devices
Authors: Liu Fangqi , Xu Jialu , Wang Tongtong , Yu Qiang , Wang Wenyue , Zhang Yong , Wu Jian , Zhu Sicong
Published: November 2022

Black arsenical phosphorus (b-AsP), a derivative of black phosphorus, is a bimetallic alloy compound with the advantage of high carrier mobility, high stability, and tailorable configuration. However, lack of an effective tool to facilitate the application of AsP as a magnetic device. Herein, band gap modulation and the introduction of magnetism can be achieved by doping non-metallic atoms in three different AsP configurations. And the doping of the same atom will cause variation in the electronic structure depending on the configuration. Surprisingly, doping with both enriched elements C and O transforms AsP into a magnetic material. Furthermore, the source of the magnetic moment is explained by solving the wave function of the doped AsP, which is caused by the orbital coupling of the C and O atoms to AsP. To excavate the potentials of this magnetic AsP system for magnetic devices, field-effect transistors based on two doped armchair AsP3 nanoribbons are simulated. The devices show considerable negative differential conductivity effect and good spin filtering efficiency. These findings suggest that AsP doping with enriched elements C and O could be an excellent candidate for future spintronics applications.