bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemical Transformations in Proto-Cytoplasmic Media. Phosphorus Coupling in the Silica Hydrogel Phase
Authors: Gorrell Ian , Henderson Timothy , Albdeery Kamal , Savage Philip , Kee Terence
Published: November 2017

It has been proposed that prebiotic chemical studies on the emergence of primitive life would be most relevant when performed in a hydrogel, rather than an aqueous, environment. In this paper we describe the ambient temperature coupling of phosphorus oxyacids [Pi] mediated by Fe(II) under aerobic conditions within a silica hydrogel (SHG) environment. We have chosen to examine SHGs as they have considerable geological precedence as key phases in silicification en route to rock formation. Following a description of the preparation and characterization studies on our SHG formulations, coupling experiments between Pi species are described across multiple permutations of (i) Pi compound; (ii) gel formulation; (iii) metal salt additive; and (iv) pH-modifying agent. The results suggest that successful Pi coupling, indicated by observation of pyrophosphate [PPi(V)] via 31P-NMR spectroscopy, takes place when the following components are present: (i) a mixture of mixture of Pi(III) and Pi(V) or pure PPi(III-V); (ii) Fe(II); (iii) acetic or formic acid (not hydrochloric acid); (iv) aerobic conditions or the presence of H2O2 as an oxidant; and (v) the presence of a gel system. On the basis of these, and aqueous control reactions, we suggest mechanistic possibilities.
Novel Montmorillonite/TiO2/MnAl-Mixed Oxide Composites Prepared from Inverse Microemulsions as Combustion Catalysts
Authors: Napruszewska Bogna , Michalik-Zym Alicja , Rogowska Melania , Bielańska Elżbieta , Rojek Wojciech , Gaweł Adam , Wójcik-Bania Monika , Bahranowski Krzysztof , Serwicka Ewa
Published: November 2017

A novel design of combustion catalysts is proposed, in which clay/TiO2/MnAl-mixed oxide composites are formed by intermixing exfoliated organo-montmorillonite with oxide precursors (hydrotalcite-like in the case of Mn-Al oxide) obtained by an inverse microemulsion method. In order to assess the catalysts’ thermal stability, two calcination temperatures were employed: 450 and 600 °C. The composites were characterized with XRF (X-ray fluorescence), XRD (X-ray diffraction), HR SEM (high resolution scanning electron microscopy, N2 adsorption/desorption at −196 °C, and H2 TPR (temperature programmed reduction). Profound differences in structural, textural and redox properties of the materials were observed, depending on the presence of the TiO2 component, the type of neutralization agent used in the titania nanoparticles preparation (NaOH or NH3 (aq)), and the temperature of calcination. Catalytic tests of toluene combustion revealed that the clay/TiO2/MnAl-mixed oxide composites prepared with the use of ammonia showed excellent activity, the composites obtained from MnAl hydrotalcite nanoparticles trapped between the organoclay layers were less active, but displayed spectacular thermal stability, while the clay/TiO2/MnAl-mixed oxide materials obtained with the aid of NaOH were least active. The observed patterns of catalytic activity bear a direct relation to the materials’ composition and their structural, textural, and redox properties.
Structural, Electrical, Magnetic and Resistive Switching Properties of the Multiferroic/Ferroelectric Bilayer Thin Films
Authors: Kao Ming-Cheng , Chen Hone-Zern , Young San-Lin , Chen Kai-Huang , Chiang Jung-Lung , Shi Jen-Bin
Published: November 2017

Bi0.8Pr0.2Fe0.95Mn0.05O3/Bi3.96Gd0.04Ti2.95W0.05O12 (BPFMO/BGTWO) bilayer thin films with Multiferroic/Ferroelectric (MF/FE) structures were deposited onto Pt(111)/Ti/SiO2/Si(100) substrates by using the sol-gel method with rapid thermal annealing. The BPFMO/BGTWO thin films exhibited well-saturated ferromagnetic and ferroelectric hysteresis loops because of the electro-magnetic coupling induced by the MF/FE structure. The remnant magnetization (2Mr) and remnant polarization (2Pr) were 4.6 emu/cm3 and 62 μC/cm2, respectively. Moreover, the bipolar I-V switching curves of BPFMO/BGTWO bilayer thin films resistive random access memory (RRAM) devices were discussed, and investigated for LRS/HRS.
Morphology and Mechanical Properties of Polyimide Films: The Effects of UV Irradiation on Microscale Surface
Authors: Qu Changzi , Hu Junsong , Liu Xing , Li Zheng , Ding Yanhuai
Published: November 2017

As an attractive dielectric material, polyimide has been widely used in the field of electronics, aerospace, and automobiles due to its useful mechanical properties and good chemical resistance. UV irradiation was considered to be the main factor related to the damage and failure of polyimide. Here the effects of UV irradiation on the surface morphology and microscale mechanical properties of polyimide films are characterized by atomic force microscopy (AFM). The surface roughness of the UV-irradiated samples developed and the mechanical properties degraded with the radiation dose increased. For comparison, uniaxial tensile test was performed to obtain the macroscale Young’s modulus of polyimide film. The UV-irradiated damaging depth was simulated with finite element method (FEM).
Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells
Authors: Testa Ugo , Castelli Germana , Pelosi Elvira
Published: November 2017

Melanoma is an aggressive neoplasia issued from the malignant transformation of melanocytes, the pigment-generating cells of the skin. It is responsible for about 75% of deaths due to skin cancers. Melanoma is a phenotypically and molecularly heterogeneous disease: cutaneous, uveal, acral, and mucosal melanomas have different clinical courses, are associated with different mutational profiles, and possess distinct risk factors. The discovery of the molecular abnormalities underlying melanomas has led to the promising improvement of therapy, and further progress is expected in the near future. The study of melanoma precursor lesions has led to the suggestion that the pathway of tumor evolution implies the progression from benign naevi, to dysplastic naevi, to melanoma in situ and then to invasive and metastatic melanoma. The gene alterations characterizing melanomas tend to accumulate in these precursor lesions in a sequential order. Studies carried out in recent years have, in part, elucidated the great tumorigenic potential of melanoma tumor cells. These findings have led to speculation that the cancer stem cell model cannot be applied to melanoma because, in this malignancy, tumor cells possess an intrinsic plasticity, conferring the capacity to initiate and maintain the neoplastic process to phenotypically different tumor cells.
Coalescence Processes of Droplets and Liquid Marbles
Authors: Jin Jing , Ooi Chin , Dao Dzung , Nguyen Nam-Trung
Published: November 2017

The coalescence process of droplets and, more recently, of liquid marbles, has become one of the most essential manipulation schemes in digital microfluidics. This process is indispensable for realising microfluidic functions such as mixing and reactions at microscale. This paper reviews previous studies on droplet coalescence, paying particular attention to the coalescence of liquid marbles. Four coalescence systems have been reviewed, namely, the coalescence of two droplets freely suspended in a fluid; the coalescence of two sessile droplets on a solid substrate; the coalescence of a falling droplet and a sessile droplet on a solid substrate; and liquid marble coalescence. The review is presented according to the dynamic behaviors, physical mechanisms and experimental parameters of the coalescence process. It also provides a systematic overview of how the coalescence process of droplets and liquid marbles could be induced and manipulated using external energy. In addition, the practical applications of liquid marble coalescence as a novel microreactor are highlighted. Finally, future perspectives on the investigation of the coalescence process of liquid marbles are proposed. This review aims to facilitate better understanding of the coalescence of droplets and of liquid marbles as well as to shed new insight on future studies.
PGE Production in Southern Africa, Part II: Environmental Aspects
Authors: Buchspies Benedikt , Thormann Lisa , Mbohwa Charles , Kaltschmitt Martin
Published: November 2017

Platinum group elements (PGEs, 6E PGE = Pt + Pd + Rh + Ru + Ir + Au) are used in numerous applications that seek to reduce environmental impacts of mobility and energy generation. Consequently, the future demand for PGEs is predicted to increase. Previous studies indicate that environmental impacts of PGE production change over time emphasizing the need of up-to-date data and assessments. In this context, an analysis of environmental aspects of PGE production is needed to support the environmental assessment of technologies using PGEs, to reveal environmental hotspots within the production chain and to identify optimization potential. Therefore, this paper assesses greenhouse gas (GHG) emissions, cumulative fossil energy demand (CEDfossil), sulfur dioxide (SO2) emissions and water use of primary PGE production in Southern Africa, where most of today’s supply originates from. The analysis shows that in 2015, emissions amounted to 45 t CO2-eq. and 502 kg SO2 per kg 6E PGE in the case GHG and SO2 emissions, respectively. GHG emissions are dominated by emissions from electricity provision contributing more than 90% to the overall GHG emissions. The CEDfossil amounted to 0.60 TJ per kg 6E PGE. A detailed analysis of the CEDfossil reveals that electricity provision based on coal power consumes the most fossil energy carriers among all energy forms. Results show that the emissions are directly related to the electricity demand. Thus, the reduction in the electricity demand presents the major lever to reduce the consumption of fossil energy resources and the emission of GHGs and SO2. In 2015, the water withdrawal amounted to 0.272 million L per kg 6E PGE. Additionally, 0.402 million L of recycled water were used per kg 6E PGE. All assessed indicators except ore grades and production volumes reveal increasing trends in the period from 2010 to 2015. It can be concluded that difficult market conditions (see part I of this paper series) and increasing environmental impacts present a challenging situation for the Southern African PGE mining industry.
Quantification and Prediction of Bulk Gold Fineness at Placer Gold Mines: A New Zealand Example
Authors: Craw Dave , McLachlan Christine , Negrini Marianne , Becker Noel
Published: November 2017

This study documents the bulk Au fineness (Au parts per thousand) of the bullion from a placer gold mine in southern New Zealand. The compositions of doré bars produced approximately every 10 days over nearly three years is compared to the range of compositions of gold particles which have been extracted. Silver is the principal impurity in the gold, and the doré bars contained 2–3 wt % Ag over the period examined. At the scale of a typical individual 0.5 mm gold particle, there are three different types of gold: an Ag-bearing core (2–9 wt % Ag), a 10–50 µm wide Ag-poor rim (typically <1 wt % Ag), and micron scale overgrowth gold (0% Ag). The overgrowths are volumetrically negligible, and the average Ag content of a gold particle is controlled principally by the proportions of core and rim gold. The rims have been formed by recrystallisation of deformed core gold, with associated leaching of the Ag from the recrystallised gold. The volumetric proportion of cores has decreased with increasing flattening of gold particles, and highly flattened and folded flakes have little or no remnant cores. The bulk Au fineness of doré bars from the mine has decreased from ~980 to ~970 as the mine progressed upstream in a Pleistocene paleochannel because the upstream gold has been less flattened than the downstream gold.
Biodegradable Chitosan Decreases the Immune Response to Trichinella spiralis in Mice
Authors: Brodaczewska Klaudia , Wolaniuk Natalia , Lewandowska Katarzyna , Donskow-Łysoniewska Katarzyna , Doligalska Maria
Published: November 2017

The purpose of this study was to evaluate the potential of chitosan units released during natural degradation of the polymer to activate the immune system against T. spiralis infection. High molecular weight chitosan was injected intraperitoneally into C57BL/6 mice. Flow cytometry and cytokine concentration, measured by ELISA, were used to characterize peritoneal cell populations during T. spiralis infection. The strong chemo-attractive properties of chitosan caused considerable infiltration into the peritoneal cavity of CD11b+ cells, with reduced expression of MHC class II, CD80, CD86, Dectin-1 or CD23 receptors in comparison to T. spiralis-infected mice. After prolonged chitosan biodegradation, cell populations expressing IL-4R, MR and Dectin-1 receptors were found to coexist with elevated IL-6, IL-10, TGF-β and IgA production. IgA cross-reacted with T. spiralis antigen and chitosan. It was found that chitosan treatment attracted immune cells with low activity, which resulted in the number of nematodes increasing. The glucosamine and N-acetyl-D-glucosamine residues were recognized by wheat germ agglutinin (WGA) lectin and therefore any biodegradable chitosan units may actively downregulate the immune response to the parasite. The findings are relevant for both people and animals treated with chitosan preparations.
Enhancement of Aggregation-Induced Emission by Introducing Multiple o-Carborane Substitutions into Triphenylamine
Authors: Nishino Kenta , Uemura Kyoya , Gon Masayuki , Tanaka Kazuo , Chujo Yoshiki
Published: November 2017

The enhancement of aggregation-induced emission (AIE) is presented on the basis of the strategy for improving solid-state luminescence by employing multiple o-carborane substituents. We synthesized the modified triphenylamines with various numbers of o-carborane units and compared their optical properties. From the optical measurements, the emission bands from the twisted intramolecular charge transfer (TICT) state were obtained from the modified triphenylamines. It was notable that emission efficiencies of the multi-substituted triphenylamines including two or three o-carborane units were enhanced 6- to 8-fold compared to those of the mono-substituted triphenylamine. According to mechanistic studies, it was proposed that the single o-carborane substitution can load the AIE property via the TICT mechanism. It was revealed that the additional o-carborane units contribute to improving solid-state emission by suppressing aggregation-caused quenching (ACQ). Subsequently, intense AIEs were obtained. This paper presents a new role of the o-carborane substituent in the enhancement of AIEs.
Fabrication of Semiconductor ZnO Nanostructures for Versatile SERS Application
Authors: Yang Lili , Yang Yong , Ma Yunfeng , Li Shuai , Wei Yuquan , Huang Zhengren , Long Nguyen Viet
Published: November 2017

Since the initial discovery of surface-enhanced Raman scattering (SERS) in the 1970s, it has exhibited a huge potential application in many fields due to its outstanding advantages. Since the ultra-sensitive noble metallic nanostructures have increasingly exposed themselves as having some problems during application, semiconductors have been gradually exploited as one of the critical SERS substrate materials due to their distinctive advantages when compared with noble metals. ZnO is one of the most representative metallic oxide semiconductors with an abundant reserve, various and cost-effective fabrication techniques, as well as special physical and chemical properties. Thanks to the varied morphologies, size-dependent exciton, good chemical stability, a tunable band gap, carrier concentration, and stoichiometry, ZnO nanostructures have the potential to be exploited as SERS substrates. Moreover, other distinctive properties possessed by ZnO such as biocompatibility, photocatcalysis and self-cleaning, and gas- and chemo-sensitivity can be synergistically integrated and exerted with SERS activity to realize the multifunctional potential of ZnO substrates. In this review, we discuss the inevitable development trend of exploiting the potential semiconductor ZnO as a SERS substrate. After clarifying the root cause of the great disparity between the enhancement factor (EF) of noble metals and that of ZnO nanostructures, two specific methods are put forward to improve the SERS activity of ZnO, namely: elemental doping and combination of ZnO with noble metals. Then, we introduce a distinctive advantage of ZnO as SERS substrate and illustrate the necessity of reporting a meaningful average EF. We also summarize some fabrication methods for ZnO nanostructures with varied dimensions (0–3 dimensions). Finally, we present an overview of ZnO nanostructures for the versatile SERS application.
WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations
Authors: Riccio Gennaro , Maisto Maria , Bottone Sara , Badolati Nadia , Rossi Giovanni , Tenore Gian , Stornaiuolo Mariano , Novellino Ettore
Published: November 2017

Inhibitors of the Wingless-related Integration site (WNT)/β-catenin pathway have recently been under consideration as potential chemopreventive agents against Familial Adenomatous Polyposis (FAP). This autosomal-dominant syndrome is caused by germline mutations in the gene coding for the protein APC and leads to hyperactivation of the WNT/β-catenin signaling pathway, uncontrolled intestinal cell proliferation and formation of adenocarcinomas. The aim of the present work was to: (i) test, on in vitro cultures of cells carrying FAP mutations and on ex vivo biopsies of FAP patients, the WNT inhibitory activity of extracts from two common southern Italian apples, Malus pumila Miller cv. ‘Annurca’ and Malus domestica cv ‘Limoncella’; (ii) identify the mechanisms underpinning their activities and; (iii) evaluate their potency upon gastrointestinal digestion. We here show that both Annurca and Limoncella apple extracts act as WNT inhibitors, mostly thanks to their polyphenolic contents. They inhibit the pathway in colon cells carrying FAP mutations with active dilutions falling in ranges close to consumer-relevant concentrations. Food-grade manufacturing of apple extracts increases their WNT inhibitory activity as result of the conversion of quercetin glycosides into the aglycone quercetin, a potent WNT inhibitor absent in the fresh fruit extract. However, in vitro simulated gastrointestinal digestion severely affected WNT inhibitory activity of apple extracts, as result of a loss of polyphenols. In conclusion, our results show that apple extracts inhibit the WNT pathway in colon cells carrying FAP mutations and represent a potential nutraceutical alternative for the treatment of this pathology. Enteric coating is advisable to preserve the activity of the extracts in the colon-rectal section of the digestive tract.
Fatty Acids, Antioxidants and Physical Activity in Brain Aging
Authors: Freitas Hércules , Ferreira Gustavo , Trevenzoli Isis , Oliveira Karen , De Melo Reis Ricardo
Published: November 2017

Polyunsaturated fatty acids and antioxidants are important mediators in the central nervous system. Lipid derivatives may control the production of proinflammatory agents and regulate NF-κB activity, microglial activation, and fatty acid oxidation; on the other hand, antioxidants, such as glutathione and ascorbate, have been shown to signal through transmitter receptors and protect against acute and chronic oxidative stress, modulating the activity of different signaling pathways. Several authors have investigated the role of these nutrients in the brains of the young and the aged in degenerative diseases such as Alzheimer’s and Parkinson’s, and during brain aging due to adiposity- and physical inactivity-mediated metabolic disturbances, chronic inflammation, and oxidative stress. Through a literature review, we aimed to highlight recent data on the role of adiposity, fatty acids, antioxidants, and physical inactivity in the pathophysiology of the brain and in the molecular mechanisms of senescence. Data indicate the complexity and necessity of endogenous/dietary antioxidants for the maintenance of redox status and the control of neuroglial signaling under stress. Recent studies also indicate that omega-3 and -6 fatty acids act in a competitive manner to generate mediators for energy metabolism, influencing feeding behavior, neural plasticity, and memory during aging. Finding pharmacological or dietary resources that mitigate or prevent neurodegenerative affections continues to be a great challenge and requires additional effort from researchers, clinicians, and nutritionists in the field.
On Being Stuck: Tapping into the Creative Power of Writer’s Block by Laraine Herring. 2016. Shambhala Publications, Boulder, Colorado. US$16.95. ISBN 978-1-61180-290-0 (Paperback)
Authors: Donovan Stephen K.
Published: November 2017

n/a
The Implicit as a Resource for Engaging Normativity in Religious Studies
Authors: Slater Gary
Published: November 2017

This piece recommends the implicit as a resource for examining normativity within the study of religion. Attention to the implicit serves at least two purposes toward this end. First, it gives the scholar of religion a clearer sense of the norms of the communities she seeks to understand, norms that, depending partly on one’s methodological commitments, may be evaluated as well as described. Second, it deepens the scholar’s reflections on the implicit norms that guide her own work. These claims—which extend the work of Tyler Roberts, Kevin Schilbrack, and Thomas A. Lewis—are embedded within specific understandings of language and mind as drawn from Robert Brandom and Peter Ochs. Brandom and Ochs help speak to the questions of whether the academic study of a religious tradition can or should evaluate that tradition, answering “yes” and “it depends”, respectively. This presents scholars of religion with both a challenge and an opportunity. The challenge is that religionists no longer have recourse to a strict distinction between fact and value. The opportunity is that, by linking implicit facts and values to explicit analysis and evaluation, scholarly investigations can be expanded in both descriptive and prescriptive contexts.
Photochemical Reflectance Index (PRI) for Detecting Responses of Diurnal and Seasonal Photosynthetic Activity to Experimental Drought and Warming in a Mediterranean Shrubland
Authors: Zhang Chao , Filella Iolanda , Liu Daijun , Ogaya Romà , Llusià Joan , Asensio Dolores , Peñuelas Josep
Published: November 2017

Climatic warming and drying are having profound impacts on terrestrial carbon cycling by altering plant physiological traits and photosynthetic processes, particularly for species in the semi-arid Mediterranean ecosystems. More effective methods of remote sensing are needed to accurately assess the physiological responses and seasonal photosynthetic activities of evergreen species to climate change. We evaluated the stand reflectance in parallel to the diurnal and seasonal changes in gas exchange, fluorescence and water contents of leaves and soil for a Mediterranean evergreen shrub, Erica multiflora, submitted to long-term experimental warming and drought. We also calculated a differential photochemical reflectance index (ΔPRI, morning PRI subtracted from midday PRI) to assess the diurnal responses of photosynthesis (ΔA) to warming and drought. The results indicated that the PRI, but not the normalized difference vegetation index (NDVI), was able to assess the seasonal changes of photosynthesis. Changes in water index (WI) were consistent with seasonal foliar water content (WC). In the warming treatment, ΔA value was higher than control in winter but ΔYield was significantly lower in both summer and autumn, demonstrating the positive effect of the warming on the photosynthesis in winter and the negative effect in summer and autumn, i.e., increased photosynthetic midday depression in summer and autumn, when temperatures were much higher than in winter. Drought treatment increased the midday depression of photosynthesis in summer. Importantly, ΔPRI was significantly correlated with ΔA both under warming and drought, indicating the applicability of ΔPRI for tracking the midday depression of photosynthetic processes. Using PRI and ΔPRI to monitor the variability in photosynthesis could provide a simple method to remotely sense photosynthetic seasonality and midday depression in response to ongoing and future environmental stresses.
In Memoriam: Paolo Cappa
Authors: Palermo Eduardo , Rossi Stefano , Patanè Fabrizio , Laut Jeffrey , Porfiri Maurizio
Published: November 2017

Prof. Paolo Cappa passed away on 26 August 2016, at the age of 59, after a long and courageous fight against cancer. Paolo Cappa was a Professor in Mechanical and Thermal Measurements and Experimental Biomechanics in the Department of Mechanical and Aerospace Engineering of Sapienza University of Rome, where he had also served as the Head of the Department, and a Research Professor in the Department of Mechanical and Aerospace Engineering of New York University Tandon School of Engineering. During his intense, yet short, career, he made several significant scientific contributions within the discipline of Mechanical and Thermal Measurements, pioneering fundamental applications to Biomechanics. He co-founded the Motion Analysis and Robotics Laboratory (MARLab) within the Neurorehabilitation Division of IRCCS Pediatric Hospital “Bambino Gesu”, in Rome, to fuel transitional research from the laboratory to clinical practice. Through collaboration with neurologists and physiatrists at MARLab, Prof. Cappa led the development of a powerful array of novel mechanical solutions to wearable robotics for pediatric patients, addressing dramatic needs for children’s health and contributing to the training of an entire generation of Mechanical Engineering students.
Adsorptive Stripping Voltammetric Determination of Amaranth and Tartrazine in Drinks and Gelatins Using a Screen-Printed Carbon Electrode
Authors: Perdomo Yeny , Arancibia Verónica , García-Beltrán Olimpo , Nagles Edgar
Published: November 2017

A fast, sensitive, and selective method for the simultaneous determination of one pair of synthetic colorants commonly found mixed in food products, Amaranth (AM) and Tartrazine (TZ), based on their adsorption and oxidation on a screen-printed electrode (SPE) is presented. The variation of peak current with pH, supporting electrolyte, adsorption time, and adsorption potential were optimized using square wave adsorptive voltammetry. The optimal conditions were found to be: pH 3.2 (PBS), Eads 0.00 V, and tads 30 s. Under these conditions, the AM and TZ signals were observed at 0.56 and 0.74 V, respectively. A linear response were found over the 0.15 to 1.20 µmol L−1 and 0.15 to 0.80 µmol L−1 concentrations, with detection limits (3σ/slope) of 26 and 70 nmol L−1 for AM and TZ, respectively. Reproducibility for 17.7 µmol L–1 AM and TZ solutions were 2.5 and 3.0% (n = 7), respectively, using three different electrodes. The method was validated by determining AM and TZ in spiked tap water and unflavored gelatin spiked with AM and TZ. Because a beverage containing both AM and TZ was not found, the method was applied to the determination of AM in a kola soft drink and TZ in an orange jelly and a soft drink powder.
Random Access Performance of Distributed Sensors Attacked by Unknown Jammers
Authors: Jeong Dae-Kyo , Wui Jung-Hwa , Kim Dongwoo
Published: November 2017

In this paper, we model and investigate the random access (RA) performance of sensor nodes (SN) in a wireless sensor network (WSN). In the WSN, a central head sensor (HS) collects the information from distributed SNs, and jammers disturb the information transmission primarily by generating interference. In this paper, two jamming attacks are considered: power and code jamming. Power jammers (if they are friendly jammers) generate noises and, as a result, degrade the quality of the signal from SNs. Power jamming is equally harmful to all the SNs that are accessing HS and simply induces denial of service (DoS) without any need to hack HS or SNs. On the other hand, code jammers mimic legitimate SNs by sending fake signals and thus need to know certain system parameters that are used by the legitimate SNs. As a result of code jamming, HS falsely allocates radio resources to SNs. The code jamming hence increases the failure probability in sending the information messages, as well as misleads the usage of radio resources. In this paper, we present the probabilities of successful preamble transmission with power ramping according to the jammer types and provide the resulting throughput and delay of information transmission by SNs, respectively. The effect of two jamming attacks on the RA performances is compared with numerical investigation. The results show that, compared to RA without jammers, power and code jamming degrade the throughput by up to 30.3% and 40.5%, respectively, while the delay performance by up to 40.1% and 65.6%, respectively.
Stochastic Integration H∞ Filter for Rapid Transfer Alignment of INS
Authors: Zhou Dapeng , Guo Lei
Published: November 2017

The performance of an inertial navigation system (INS) operated on a moving base greatly depends on the accuracy of rapid transfer alignment (RTA). However, in practice, the coexistence of large initial attitude errors and uncertain observation noise statistics poses a great challenge for the estimation accuracy of misalignment angles. This study aims to develop a novel robust nonlinear filter, namely the stochastic integration H ∞ filter (SIH ∞ F) for improving both the accuracy and robustness of RTA. In this new nonlinear H ∞ filter, the stochastic spherical-radial integration rule is incorporated with the framework of the derivative-free H ∞ filter for the first time, and the resulting SIH ∞ F simultaneously attenuates the negative effect in estimations caused by significant nonlinearity and large uncertainty. Comparisons between the SIH ∞ F and previously well-known methodologies are carried out by means of numerical simulation and a van test. The results demonstrate that the newly-proposed method outperforms the cubature H ∞ filter. Moreover, the SIH ∞ F inherits the benefit of the traditional stochastic integration filter, but with more robustness in the presence of uncertainty.
Two-Dimensional Micro-/Nanoradian Angle Generator with High Resolution and Repeatability Based on Piezo-Driven Double-Axis Flexure Hinge and Three Capacitive Sensors
Authors: Tan Xinran , Zhu Fan , Wang Chao , Yu Yang , Shi Jian , Qi Xue , Yuan Feng , Tan Jiubin
Published: November 2017

This study presents a two-dimensional micro-/nanoradian angle generator (2D-MNAG) that achieves high angular displacement resolution and repeatability using a piezo-driven flexure hinge for two-dimensional deflections and three capacitive sensors for output angle monitoring and feedback control. The principal error of the capacitive sensor for precision microangle measurement is analyzed and compensated for; so as to achieve a high angle output resolution of 10 nrad (0.002 arcsec) and positioning repeatability of 120 nrad (0.024 arcsec) over a large angular range of ±4363 μrad (±900 arcsec) for the 2D-MNAG. The impact of each error component, together with the synthetic error of the 2D-MNAG after principal error compensation are determined using Monte Carlo simulation for further improvement of the 2D-MNAG.
A Loop All-Fiber Current Sensor Based on Single-Polarization Single-Mode Couplers
Authors: Zhang Hao , Jiang Junzhen , Zhang Yu , Chen Huaixi , Zhao Na , Lin Lingyan , Qiu Yishen
Published: November 2017

Low current sensitivity and insufficient system stability are two key problems in all-fiber current sensor (AFCS) studies. In order to solve the two problems, a novel AFCS combining single-polarization single-mode (SPSM) couplers and a loop structure is presented in this paper with a design that incorporates the advantages of both SPSM couplers and a loop structure. SPSM couplers are shown to simplify the AFCS system and reduce the risk of interference, and the loop structure can enhance the current sensitivity. Both theory and experiment prove that the new AFCS can simultaneously overcome two prevalent obstacles of low current sensitivity and low stability.
Surface Plasmon Resonance Sensing of Biorecognition Interactions within the Tumor Suppressor p53 Network
Authors: Moscetti Ilaria , Cannistraro Salvatore , Bizzarri Anna Rita
Published: November 2017

Surface Plasmon Resonance (SPR) is a powerful technique to study the kinetics of biomolecules undergoing biorecognition processes, particularly suited for protein-protein interactions of biomedical interest. The potentiality of SPR was exploited to sense the interactions occurring within the network of the tumor suppressor p53, which is crucial for maintaining genome integrity and whose function is inactivated, mainly by down regulation or by mutation, in the majority of human tumors. This study includes p53 down-regulators, p53 mutants and also the p53 family members, p63 and p73, which could vicariate p53 protective function. Furthermore, the application of SPR was extended to sense the interaction of p53 with anti-cancer drugs, which might restore p53 function. An extended review of previous published work and unpublished kinetic data is provided, dealing with the interaction between the p53 family members, or their mutants and two anticancer molecules, Azurin and its cell-penetrating peptide, p28. All the kinetic results are discussed in connection with those obtained by a complementary approach operating at the single molecule level, namely Atomic Force Spectroscopy and the related literature data. The overview of the SPR kinetic results may significantly contribute to a deeper understanding of the interactions within p53 network, also in the perspective of designing suitable anticancer drugs.
Leishmanicidal Activity of Biogenic Fe3O4 Nanoparticles
Authors: Khatami Mehrdad , Alijani Hajar , Sharifi Iraj , Sharifi Fatemeh , Pourseyedi Shahram , Kharazi Sam , Lima Nobre Marcos Augusto , Khatami Manouchehr
Published: November 2017

Abstract: Due to the multiplicity of useful applications of metal oxide nanoparticles (ONPs) in medicine are growing exponentially, in this study, Fe3O4 (iron oxide) nanoparticles (IONPs) were biosynthesized using Rosemary to evaluate the leishmanicidal efficiency of green synthesized IONPs. This is the first report of the leishmanicidal efficiency of green synthesized IONPs against Leishmania major. The resulting biosynthesized IONPs were characterized by ultraviolet-visible spectroscopy (UV-Vis), X-ray diffraction (XRD), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FTIR). The leishmanicidal activity of IONPS was studied via 3-4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The results showed the fabrication of the spherical shape of monodisperse IONPs with a size 4 ± 2 nm. The UV-visible spectrophotometer absorption peak was at 334 nm. The leishmanicidal activity of biogenic iron oxide nanoparticles against Leishmania major (promastigote) was also studied. The IC50 of IONPs was 350 µg/mL. In this report, IONPs were synthesized via a green method. IONPs are mainly spherical and homogeneous, with an average size of about 4 nm, and were synthesized here using an eco-friendly, simple, and inexpensive method.
Sustainable Governance for the Opened Electric Vehicle Charging and Upgraded Facilities Market
Authors: Wu Tian , Zeng Bohan , He Yali , Tian Xin , Ou Xunmin
Published: November 2017

Since the China State Grid opened the market for infrastructure construction of electric charging stations and allowed Tesla, Potevio, BAIC BJEV and other enterprises to provide their own charging stations and other infrastructure construction, the development of electric vehicles has been greatly affected. How to maintain a sustainable governance in the opened electric vehicle charging and upgraded facilities market is an important policy issues. This paper presents a monopolistic competition model for the differentiated products market and addresses several issues related to Cournot equilibrium to illustrate why the expected free market actually operates in a monopolistic competition market structure. The analytic solution of the model shows that whether the extent of firm entry is insufficient, excessive or optimum is determined by consumers’ time preference, level of production differentiation and features of cost structure, including fixed cost and marginal cost. The sensitivity analysis has been performed among the above factors and tracked some other factors which would determine the effect of the new policy issues. The main policy suggestion is that the government should optimize entry regulations and lay down the criterion of charging interface standards for charging stations to avoid the electric vehicle charging and upgraded facilities marketization process of a one-size-fits-all solution and form a monopolistic competition market.
Tradeoff between User Quality-Of-Experience and Service Provider Profit in 5G Cloud Radio Access Network
Authors: Afrin Mahbuba , Razzaque Md. , Anjum Iffat , Hassan Mohammad , Alamri Atif
Published: November 2017

In recent years, the Cloud Radio Access Network (CRAN) has become a promising solution for increasing network capacity in terms of high data rates and low latencies for fifth-generation (5G) cellular networks. In CRAN, the traditional base stations (BSs) are decoupled into remote radio heads (RRHs) and base band units (BBUs) that are respectively responsible for radio and baseband functionalities. The RRHs are geographically proximated whereas the the BBUs are pooled in a centralized cloud named BBU pool. This virtualized architecture facilitates the system to offer high computation and communication loads from the impetuous rise of mobile devices and applications. Heterogeneous service requests from the devices to different RRHs are now sent to the BBUs to process centrally. Meeting the baseband processing of heterogeneous requests while keeping their Quality-of-Service (QoS) requirements with the limited computational resources as well as enhancing service provider profit is a challenging multi-constraint problem. In this work, a multi-objective non-linear programming solution to the Quality-of-Experience (QoE) and Profit-aware Resource Allocation problem is developed which makes a trade-off in between the two. Two computationally viable scheduling algorithms, named First Fit Satisfaction and First Fit Profit algorithms, are developed to focus on maximization of user QoE and profit, respectively, while keeping the minimum requirement level for the other one. The simulation environment is built on a relevant simulation toolkit. The experimental results demonstrate that the proposed system outperforms state-of-the-art works well across the requests QoS, average waiting time, user QoE, and service provider profit.
Towards Sustainable Land Use in China: A Collection of Empirical Studies
Authors: Xie Hualin
Published: November 2017

Achieving sustainable land use is one of the most important ways to achieve regional socio-economic sustainable development. We have collected 12 papers in this special issue “Sustainable Land Use in China” to show the varied application of sustainable land use studies and to provide meaningful decision-making information and policy implications for land use planners. We summarize the contributions to this special issue on sustainable land use and place them in perspective. Several studies focus on sustainable urban land use, some focus on sustainable rural land use, and others on environmental issues on land use. These studies have analyzed a broad array of topics related to land use, including the dynamic changes and driving forces of land use spatial patterns, sustainable land use, land use policy and optimization, and the environmental problems related to certain types of land use.
Sustainable Block Design Process for High-Rise and High-Density Districts with Snow and Wind Simulations for Winter Cities
Authors: Watanabe Norihiro , Setoguchi Tsuyoshi , Maeda Kosuke , Iwakuni Daiki , Guo Zhiming , Tsutsumi Takuya
Published: November 2017

Urban designs that consider regional climatic conditions are one of the most important approaches for developing sustainable cities. In cities that suffer from heavy snow and cold winds in winter, an urban design approach different than that used for warm cities should be used. This study presents a scientific design process (the sustainable design approach) that incorporates environmental and energy assessments that use snow and wind simulations to establish guidelines for the design of urban blocks in high-rise and high-density districts so that the impact of snow and wind can be minimized in these cities. A city block in downtown Sapporo, Japan, was used as a case study, and we evaluated four conceptual models. The four models were evaluated for how they impacted the snow and wind conditions in the block as well as the snow removal energy. Based on the results, we were able to identify the design guidelines in downtown Sapporo: an urban block design with higher building height ratio without the mid-rise part can reduce the snowdrifts and lower the snow removal energy. The proposed sustainable urban design approach would be effective in improving the quality of public spaces and reducing snow removal energy in winter cities.
How Third-Party CSR Evaluation Matters: Keeping Up with Rivals in CSR Performance Ratings of Korean Firms, 2011–2015
Authors: Hyun Eunjung
Published: November 2017

Does corporate social responsibility (CSR) evaluation by third-party entities (i.e., external agencies, including civic organizations) affect the CSR performance of firms? This article explores the question of whether and how third-party CSR ratings change the subsequent CSR behavior and hence performance of rated firms. Combining insights from the research on ratings/rankings and a behavioral theory of firms, we hypothesize that firms with large negative CSR rating gaps—i.e., CSR ratings below the industry average—are more prone to improving their subsequent CSR behavior, and hence performance ratings, than those with small negative gaps, because of the desire to avoid being viewed as CSR laggards relative to their industry rivals. As a result, efforts are directed at enhancing CSR performance. Empirical support for this conjecture is found through random effect regression analyses of publicly listed firms in Korea that were rated by the KEJI (Korean Economic Justice Institute) during 2011–2015 with respect to multiple dimensions of CSR. Further results show that the positive effect of negative CSR rating gaps on subsequent CSR ratings appears only in the firms without well-established reputations, suggesting the possibility that firms with weak reputations have stronger incentives to keep up with other industry incumbents in CSR performance ratings than their counterparts.
Health Risk Assessment of Vegetables Grown on the Contaminated Soils in Daye City of Hubei Province, China
Authors: Yang Jun , Lv Fuhong , Zhou Jingcheng , Song Yongwei , Li Fei
Published: November 2017

China is an agriculturally-producing country and the safety of its vegetables will have an extensive attention at home and abroad. Recently, contamination of soils and vegetables caused by mining activities is of great social concern because of the potential risk to human health, especially to the residents whom live near metal or metalloid mines. In this study, 18 topsoil and 141 vegetable samples were collected from the contaminated areas in Daye City Hubei Province, China and the concentrations of copper (Cu), zinc (Zn), arsenic (As), cadmium (Cd) and lead (Pb) were analyzed. A self-designed questionnaire was assigned to obtain the exposure scenario and the USEPA health risk assessment model was adopted to assess two type of risks (non-carcinogenic risks and carcinogenic risks) of vegetables to humans. The results showed that the average contents of metal(loid)s in soils exceeded the background value of Daye City. The average contents of metal(loid)s, especially As, Cd, Pb, in three kinds of vegetables were significantly higher than the permissible values based on Chinese national standard. Leafy vegetables had relatively higher concentrations and the transfer factors of As (0.015), Cd (0.080) and Pb (0.003) were comparable to leguminous and fruit vegetables. Leguminous vegetables had relatively higher concentrations and transfer factors of Cu (0.032) and Zn (0.094) than leafy and fruit vegetables. The transfer factors from soil to plants follows a decreasing order as Cd (0.068), Zn (0.047) > Cu (0.023) > As (0.006), Pb (0.002). Furthermore, health risk assessment revealed the following results: the non-carcinogenic risk decreased in the order of children, adult, adolescent, while the carcinogenic risk followed a decreasing order of adult, adolescent, children; the calculated carcinogenic and non-carcinogenic risk of the metal(loid)s by vegetable consumption decreased in the order of leafy vegetables > fruit vegetables > leguminous vegetables. The relatively lower transfer factors and lower risks may suggest that leguminous and fruit vegetables are more suitable for planting in Daye City. Based on the contributions of five kinds of metal(loid)s from three types of vegetables, Cd and As are found to be the dominant sources of health risk.
On the Sustainability of Co-Authoring Behaviors in Vietnamese Social Sciences: A Preliminary Analysis of Network Data
Authors: Ho Tung , Nguyen Hong , Vuong Thu-Trang , Vuong Quan-Hoang
Published: November 2017

The topic of sustainability has mostly been tied to economic development and environmental protection, yet not much attention has been paid to the need for high problem-solving capacity as this underlines both issues. One of the most straightforward ways to improve problem-solving capacity is to nurture ‘productive and enduring’, i.e., sustainable, scientific communities. The study examines the co-authoring behaviors of 412 Vietnamese social scientists over the 2008–2017 period via social network analysis to determine if these researchers have formed sustainable scientific communities, using Scopus data. The dataset provides an insightful look into the predominant form of collaboration, i.e., co-authorship, within the Vietnamese social science research communities. Through basic network metrics such as density and clustering coefficient, the study hypothesizes that the socially sustainable research communities are those with low clustering and high density. As any scholar's position in a network can be specified by three quantities: the number of publications, connections, and years in research, the distance metrics from the most productive to the rest are computed and compared. The study hypothesizes that if the distance is too large; it reflects the socially unsustainable situation in the network. The results indicate that certain level of social unsustainability exists in social sciences groups in Vietnam. Though the results are only indicative, it has opened up a fertile space for future inquiry into this matter.