bluuebunny/crossref_metadata_2025 huggingface dataset:
The direction of primary lateral spinal curvature and distribution of body mass on base of support in children with scoliosis I°
Authors: Siwiec Andrzej , Domagalska-Szopa Małgorzata , Kwiecień-Czerwieniec Ilona , Szopa Andrzej
Published: September 2022

Introduction. As a result of subjective functional assessment, disturbances in the symmetry of body weight distribution on the support plane are commonly observed in children and adolescents with idiopathic scoliosis. The objective of this study was to identify the relationship between the direction of the primary curvature and the body weight distribution on the ground in children with idiopathic scoliosis. Method. Two groups (the study group and the control group) of children aged 7–11 were included in the study. The study group consisted of 96 children rehabilitated due to scoliosis in rehabilitation centres. The control group included children of the corresponding age, height and weight in comparison to the study group. The main element of the study involved measurements of the percentage body weight distribution on the support plane between the “convex” and “concave” side of the body while maintaining a standing position on both legs. Results. Based on the value of the symmetry index and the direction of the primary curvature, the following subgroups were distinguished among the children with scoliosis: children with symmetrical body weight distribution on the support plane (21%); children with asymmetric body weight distribution on the support plane overloading the convex side (51%) and children overloading the concave side (28%). Conclusion. The occurrence of symmetry disorders in the body weight distribution on the support plane in children with idiopathic scoliosis requires taking these features into account in the early stage of rehabilitation of these children.
Multiplikasi Murid Kristus Berdasarkan 2 Timotius 2:2 Di Gereja POUK Ichthus Bumi Dirgantara Permai Di Bekasi
Authors: Ruku Noh , Trosmada Ucok
Published: September 2022

Artikel ini memuat tentang sebuah penelitian yang dilakukan untuk menemukan Multiplikasi Murid Kristus dalam 2 Timotius 2:2 di Gereja POUK Ichthus Bumi Dirgantara Permai, dengan mengunakan paradigma naturalistis atau paradigma alamiah berdasarkan filsafat fenomologis dan metode penelitian kualitatif.

Tema-tema yang ditemukan adalah bahwa: Amanat Agung ditujukan bagi semua murid Yesus yaitu menjadikan semua bangsa murid Tuhan Yesus; Proses ini tidak hanya berhenti ketika seseorang telah menjadi murid, tetapi seorang murid yang bertanggung jawab untuk mempersiapkan murid lain agar dapat memuridkan lagi. Dengan cara ini maka akan terjadi multiplikasi murid Kristus.

Dalam 2 Timotius 2:2, Rasul Paulus menunjukkan suatu model yang ideal agar terjadi multiplikasi, Paulus (generasi pertama) meminta muridnya yaitu Timotius (generasi kedua) agar mempersiapkan orang-orang yang dapat dipercayai (generari ketiga) untuk mengajar orang lain (generasi keempat). 

Tesis ini direkomendasikan kepada gembala jemaat, rohaniwan dan pelayan dengan latar belakang teologi, majelis, pengerja, pengurus gereja serta jemaat yang terlibat dalam penjangkauan dan pemuridan.
Analisis Sektor Unggulan di Provinsi Kalimantan Barat
Authors: Modes Jeberta Tefilah , Hidayah Rini Nurul
Published: September 2022

Pertumbuhan ekonomi merupakan gambaran tentang pembangunan ekonomi di suatu daerah. Provinsi Kalimantan Barat merupakan provinsi dengan luas wilayah terbesar keempat di Indonesia. Oleh karena itu, membangun wilayah yang luas ini perlu ditetapkan langkah-langkah yang tepat dalam program pembangunan di wilayah Kalimantan Barat. Dengan demikian, tujuan dari penelitian ini adalah untuk mengetahui sektor unggulan bagi perekonomian Kalimantan Barat. Dengan menggunakan analisis Klassen Typology Method, Location Quotient, dan analisis Shift Share diperoleh empat sektor unggulan yaitu sektor pertanian, kehutanan, dan perikanan; pengadaan air, pengelolaan sampah, limbah dan daur ulang; administrasi pemerintahan, pertahanan dan jaminan sosial wajib; serta jasa kesehatan dan kegiatan sosial.
Determinan Perkawinan Anak pada Wanita Usia Muda di Provinsi Kalimantan Barat Tahun 2020
Authors: Mustika Diva Arum , Adib Achmad Tasylichul
Published: September 2022

Indonesia menempati peringkat ke-8 di dunia dan ke-2 di Asia Tenggara untuk kasus perkawinan anak. Terdapat 11,21 persen perempuan berumur 20 – 24 tahun di Indonesia yang menikah sebelum berumur 18 tahun dan 20 provinsi di antaranya memiliki prevalensi perkawinan anak yang masih di atas rata-rata nasional pada tahun 2018, termasuk Provinsi Kalimantan Barat. Masih tingginya prevalensi perkawinan anak menimbulkan masalah kependudukan yang lain seperti kekerasan dalam rumah tangga, perceraian, serta kesehatan ibu dan anak. Tujuan dari penelitian ini yaitu memberikan gambaran umum karakteristik dan mengetahui variabel-variabel yang berpengaruh serta menganalisis kecenderungannya terhadap perkawinan anak pada wanita usia muda di Provinsi Kalimantan Barat tahun 2020. Hasil penelitian ini menunjukkan 1 dari 3 wanita usia muda melangsungkan perkawinan anak. Variabel yang berpengaruh pada status umur kawin pertama pada wanita usia muda di Provinsi Kalimantan Barat tahun 2020 yaitu pendidikan tertinggi wanita, status kemiskinan, dan sumber utama penerangan rumah tangga.
Analysis of Leading Sectors and Characteristics of Provincial Economic Growth in Indonesia
Authors: Tri Subhi Khusnudin , Al Azkiya Azka
Published: September 2022

Gross Domestic Product or GDP is one indicator of a country's economy moving the economic sector. The Covid-19 pandemic caused the economy of Indonesia in the second quarter of 2020 compared to the second quarter of 2019 (YoY) to experience a 5.32 percent contraction. In increasing the economic growth rate, adjusting it to each region's potential is necessary, which is the leading sector. This study aims to analyze the basic or leading sectors and the economic growth conditions of the provinces in Indonesia and group the provinces based on their proximity characteristics. The method used is the Ward and Location Quotient using secondary data from Statistics Indonesia. The results show that 25 provinces in Indonesia have an agricultural base sector. The mining sector is primarily concentrated in eastern Indonesia and tends not to affect the Covid-19 because it can grow fast. Provinces with a manufacturing industrial base sector are focused on Java. The clustering results formed 5 clusters, each province having similar characteristics. The growing cluster is a province with a mining base sector. The sector with intense contraction is a province that provides accommodation, food, and drink. Local governments can restore the economy starting from the base sector.
Persepsi Kepuasan Kerja di Perguran Tinggi
Authors: Chayatun Machsunah Yayuk , Nurdiana Ratna
Published: September 2022

This study aims to determine how much influence employee job satisfaction at PGRI Adi Buana University (UNIPA) Surabaya PSDKU Lamongan has. Job satisfaction is an individual's emotional state that can be expressed in feelings of happiness and positive emotions and this comes from an assessment of a job or work experience which can later affect performance performance, either directly or indirectly. This research is descriptive. The population and samples used were employees at UNIPA Surabaya PSDKU Lamongan, from BAAK (Bureau of Academic and Student Administration), and BAUK (Bureau of General Administration and Finance). The results of this study indicate that employee job satisfaction is not only about the salary received but there are several factors that influence it
Diagnóstico de doença de Addison por meio de lesão cutânea na Atenção Primária
Authors: Brugugnolli Izabela , Leite Ana Olívia Guedes , Arantes Giovanna Emanuella Piffer Soares , Arf Leonardo Valentini , Faccioli João Pedro Martoneto , Claudino Luis Gustavo Cunha
Published: September 2022

A doença de Addison, ou insuficiência adrenal primária, é uma doença insidiosa e rara, que pode apresentar altas taxas de morbi-mortalidade quando o seu diagnóstico não é reconhecido e o seu tratamento não é iniciado precocemente. Apresenta sintomas variados, entre eles destacando-se hipotensão arterial, hiperpigmentação cutânea, hiponatremia e hipercalemia. Quando não tratada, pode evoluir com crise adrenal e colapso cardiovascular. O diagnóstico da doença de Addison é feito clinicamente e através dos achados, em exames laboratoriais, de concentrações elevadas do hormônio adrenocorticotrófico (ACTH) e de baixas concentrações de cortisol no plasma.  O tratamento depende da causa e requer abordagem multidisciplinar, mas em geral se faz com reposição de glicocorticoides e, ocasionalmente, demais hormônios. Este artigo descreve um caso de Doença de Addison diagnosticada na Atenção Primária à saúde, situação esta que não é comum, já que a doença apresenta sintomas clínicos bastante inespecíficos, principalmente em seus estágios iniciais, e frequentemente não é um diagnóstico considerado.

Palavras Chave: Doença de Addison; Insuficiência Adrenal Primária; Relato de caso; Atenção primária à saúde.
NFV-TE: Uma Ferramenta para a Geração Automática de Funções Virtuais Rede para Engenharia de Tráfego
Authors: Quiles Felipe Ribeiro , Moreira João Vitor , Fulber-Garcia Vinicius , Duarte Jr. Elias P.
Published: September 2022

A expansão sem precedentes das redes levou a um extraordinário aumento do tráfego. A engenharia de tráfego consiste de mecanismos relacionados ao monitoramento, caracterização, modelagem e controle do tráfego, visando garantir o bom desempenho da rede. Este trabalho descreve a ferramenta NFV-TE para geração de funções virtuais de rede para engenharia de tráfego. O paradigma NFV (Network Function Virtualization) traz grande flexibilidade às redes ao permitir a implementação de funções do núcleo em um plano de software. A partir de dados fornecidos na entrada pelo operador de rede, o NFV-TE faz a consolidação em um arquivo JSON, e gerada a função virtual de rede correspondente. O sistema foi projetado para apresentar grande facilidade para inclusão e configuração de funções. O artigo descreve diversos policers e shapers gerados NFV-TE, destacando a facilidade de configuração e demonstrando sua execução em diversos cenários e para diferentes perfis de tráfego de rede.
T800: ferramenta de firewall e benchmark para IoT
Authors: Monici Pedro H. Borges , Fernandes Gabriel Victor C. , Guibo César H. de Araujo , Bertoli Gustavo de Carvalho , Santos Aldri , Pereira Jr. Lourenço Alves
Published: September 2022

Segurança Cibernética é crucial para a transformação digital, pois muitos ativos computacionais ficam expostos na rede. Além disso, observam-se poucas soluções para proteção de dispositivos de Internet das Coisas. Assim, este artigo apresenta o filtro de pacotes T800, capaz de filtrar pacotes com baixo consumo computacional. Os resultados evidenciam a eficiência do T800 por meio de implementação e experimentação através do microcontrolador ESP32. Mais ainda, o T800 foi capaz de aumentar a disponibilidade computacional do dispositivo tendo em vista que o tráfego malicioso é excluído do processamento durante os ataques.
Análise de desempenho de estratégias de autoscaling vertical e horizontal: um estudo de caso com o Kubernetes
Authors: Akshlley Kewyn , Carvalho Marcus , Lopes Raquel
Published: September 2022

Aplicações escaláveis podem adotar estratégias de autoscaling horizontal ou o vertical para provisionar recursos na nuvem. Para ajudar na escolha da melhor estratégia, este trabalho visa comparar o desempenho do autoscaling horizontal e vertical no Kubernetes. Através de experimentos de medição usando carga sintética em uma aplicação web, o autoscaling horizontal se mostrou mais eficiente, reagindo mais rapidamente às variações da carga e tendo um menor impacto no tempo de resposta da aplicação.
B5GSim - Um Simulador para Redes Beyond 5G
Authors: Tinini Rodrigo Izidoro , Santos Matias R. P. dos , Figueiredo Gustavo Bittencourt , Batista Daniel Macêdo , Kamienski Carlos
Published: September 2022

O uso de Computação em Nuvem e Névoa, Virtualização das Funções de Rede e redes de transporte baseadas no protocolo enhanced Common Public Radio Interface (eCPRI), são os pilares das futuras redes Beyond 5G (B5G). Por meio dessas tecnologias, tais redes podem operar de forma energeticamente eficiente enquanto oferecem ampla cobertura e altas taxas de transmissão aos usuários móveis em cenários de rede de grande escala. Entretanto, como não é trivial construir cenários de experimentação para tais redes, ferramentas de simulação são utilizadas para avaliá-las. Assim, neste artigo apresentamos o simulador B5GSim, uma ferramenta especialista na simulação de redes 5G e B5G.
Impacto da Anonimização do Tráfego em Redes na Identificação de Dispositivos e na Detecção de Anomalias
Authors: Portela Ariel L. C. , Costa Wanderson L. , Menezes Rafael A. , Gomes Rafael L.
Published: September 2022

Atualmente, um aspecto crucial para o gerenciamento de redes é o monitoramento de tráfego de rede, onde técnicas de Aprendizagem de Máquina (ML) têm sido usadas sobre esses dados a fim de realizar diversas tarefas, como por exemplo identificação de dispositivos IoT e detecção de anomalias de rede. Contudo, o acesso a informações sobre o tráfego de rede pode afetar a privacidade dos usuários, ferindo assim as leis de privacidade existentes. Dentro deste contexto, este artigo analisa o impacto da anonimização de tráfego de rede, para garantir privacidade, sobre essas soluções de identificação de dispositivos e detecção de anomalias, a partir de técnicas de seleção de características. Os experimentos realizados utilizaram um conjunto de dados real, onde os resultados mostram que, quando utilizadas as técnicas de seleção e ML combinadas, a anonimização do tráfego reduz a capacidade de identificação, preservando assim a privacidade dos usuários, enquanto que mantêm a capacidade de detecção de anomalias de rede.
Otimização de Desempenho no Desenvolvimento de Jogos
Authors: Targino Thiago Luiz Alves , Moreano Nahri
Published: September 2022

O avanço da indústria de jogos digitais, para entretenimento e aplicações sérias, resultou em uma alta demanda de recursos computacionais. Técnicas de otimização podem ser aplicadas para possibilitar a execução dos mesmos atendendo a requisitos de desempenho e de custo do hardware. Este artigo descreve e exemplifica diversas otimizações que visam melhorar o desempenho de jogos digitais. Um conjunto de experimentos é apresentado, onde algumas otimizações são implementadas e os resultados de desempenho obtidos analisados.
Memórias Não Voláteis: Uma visão geral sobre as principais tecnologias, suas características e níveis de maturidade
Authors: Laks Pedro Ferro , Francesquini Emílio
Published: September 2022

Recentemente vem chamando a atenção o avanço nas pesquisas de novas tecnologias de memória que buscam unificar as memórias de trabalho e secundária. Neste artigo detalhamos o atual estado de desenvolvimento das principais tecnologias com esse objetivo, sendo elas chamadas de memórias emergentes, ou memórias persistentes ou SCM (Storage Class Memory). Além de descrever a evolução tecnológica de cada memória, essa revisão leva em conta as características operacionais de cada tecnologia. Esperamos com isto fornecer um material de referência sobre quais tecnologias atualmente merecem uma maior atenção. Algumas delas têm uma melhor perspectiva no curto prazo, já outras, devem levar alguns anos até se tornarem alternativas mais maduras.
Ambiente Domiciliar Assistido para o Monitoramento Remoto de Idosos em Zonas Rurais
Authors: Silveira Walkíria G. S. , Dantas Mario A. R.
Published: September 2022

Com o envelhecimento populacional e a preocupação em manter a atenção primária à saúde de toda a população, somada à preocupação com os cuidados aos idosos moradores de zonas rurais, a presente artigo propõe um modelo para o monitoramento remoto de idosos em um Ambiente Domiciliar Assistido, onde existe dificuldade de acesso à internet, que considera o modelo computacional de Edge-Fog-Cloud para prover um ambiente adequado. Apresenta-se um estudo da proposta de modelo e simulação do cenário em um ambiente simulador de contexto em software. Como resultado deste artigo, é possível entender a necessidade de um modelo considerando 3 níveis, levando-se em conta comunicação e computação com o objetivo de uma higienização otimizada dos dados digitais oriundos de IoT, a serem armazenados na cloud.
Avaliação de desempenho de transações em protocolos blockchain: um estudo de caso com Ethereum
Authors: Oliveira Danilo Bizarria de , Amaral Geraldo Lucas Fernandes do , Macedo Markel Pedrosa Duarte de , Mesquita Matheus Ferreira , Bianchini Calebe de Paula
Published: September 2022

Sistemas de processamento de transações são parte essencial de negócios online, e exigem tanto confiança quanto desempenho para entregar o serviço esperado. Uma ferramenta de blockchain é capaz de oferecer escalabilidade e confiança na validação de transações. A abordagem proposta neste trabalho é da avaliação do potencial de escalabilidade da rede Ethereum, e seu comportamento em cenários progressivamente mais distribuídos. Com destaque para um aumento observado de cerca de 10× o número de transações por segundo, quando comparados um nó isolado e uma rede de 16 nós, esta que também proporcionou uma queda de mais da metade da latência com relação ao cenário centralizado.
Emprego da tecnologia AVX-512 para aceleração do algoritmo POPF
Authors: Libório André , Baldassin Alexandro , Papa João Paulo
Published: September 2022

Com a popularização da tecnologia de vetorização AVX-512 na última década, tornou-se interessante verificar seu desempenho em novas aplicações. Este artigo apresenta um estudo sobre o uso da tecnologia AVX512 em um algoritmo de aprendizado de máquina baseado em grafos, o Parallel Optimum-Path Forest (POPF). Os experimentos conduzidos mostram um ganho de desempenho de até 64% em relação à versão original, sem vetorização, e até 23% em relação ao AVX2. Os ganhos em desempenho foram mais discretos em cenários em que multithreading também é utilizado, mas mesmo assim a versão com AVX-512 atingiu os melhores resultados no geral.
Making the most of what you pay for by delaying tasks to improve overall cloud instance performance
Authors: Sodré Daniel Bougleux , Boeres Cristina , Rebello Vinod E. F.
Published: September 2022

Resource elasticity and server consolidation have long been among two of cloud computing’s most relevant management tools. Yet, exemplified with a scientific application use case, this paper highlights how judicious scheduling of tasks can help maximize resource utilization and improve performance and costs for both users and cloud providers. Developing an efficient cloud service for DNA sequence comparisons is adopted as a motivating use case. Using the bioinformatics tool MASA that finds an optimal pair-wise sequence alignment, we propose a model for co-scheduling multiple alignments on a single cloud instance. The resulting, practically optimal, non-preemptive schedule can effectively double the throughput of MASA-based sequence alignment workflows.
Perspective Chapter: Accelerated Change for the Good (ACG™) Facilitator – A Transformational Approach to Perform Continuous Improvement (CI)
Authors: Wowczuk Andrew , Wowczuk Yurij , Wowczuk Zenovy , Wowczuk Borys
Published: September 2022

This chapter introduces an updated Kaizen-based concept of facilitation through a uniquely guided organizational approach and certification program. The Accelerated Change for the Good (ACG) Facilitator program was developed exclusively by the Civil-Military Innovation Institute (CMI2). The contents of the program follow best practices in Lean and Six Sigma methods using DMAIC (Define, Measure, Analyze, Improve, and Control) problem-solving techniques and stress modern facilitation skills. From an implementation perspective, ACG accelerates an organization’s initiation of continuous improvement (CI) by overcoming the constraints of traditional Lean/Six Sigma deployments. The ACG framework has been structured into an interactive 30 h of contact time using various blended knowledge transfer techniques. To obtain certification, a student must complete all workshop activities, pass a 50-question web-based quiz, and submit written evidence of leading or participating in a live event by applying the tools and techniques provided. The submittal of an event requires documentation by an exclusive workbook provided in the workshop. The program has been approved as a micro-credential activity at SUNY Maritime College and will be rolled out to several other academic institutions in the next 24 months. CMI2 has customized the program to meet client needs and has delivered the contents using both classroom and virtual platforms (e.g., Zoom, MS Teams) with a diversified cross-functional mix of participants. The research initially conducted during the formative stages of this framework consisted of a review of the lean management, continuous improvement, and operational excellence literature with a particular view toward defined and tested models (e.g., Toyota Production System, Danaher Business System). Particular emphasis was placed on methods that were applicable for a variety of industries and organizational/business structures, and that emphasized sustainability, human capital development, and focus on innovation.
Perspective Chapter: Disability-Inclusive Sustainable Services – The Role of Social Workers
Authors: Naami Augustina , Adoma Parry Rita , Ofori Alfred
Published: September 2022

Over the years, social workers have played diverse roles in engaging individuals, groups, families, communities, and organisations in their quest to promote overall well-being. However, persons with disabilities (PWDs) continue to face several challenges. The COVID-19 pandemic adds a layer to their vulnerabilities. While several interventions have been put in place to address the needs of persons with disabilities in developed countries, their counterparts in low-income countries, such as Ghana, continue to face marginalisation and exclusion. Using user-perspective and co-production approaches, we analyse existing services for Ghanaians with disabilities and the relevance and usefulness of these services. We also attempt unpack the complexities of both service providers and recipients. We conclude with strategies to help social workers develop interventions to promote sustainable disability-inclusive services.
Solid Solution Strengthening in High-Entropy Alloys
Authors: Ondicho Ibrahim , Alunda Benard , Kamau Kahinga
Published: September 2022

This book chapter discusses solid solution strengthening (SSS) as one of the main hardening mechanisms in high-entropy alloys (HEAs) that form basis as one of its core effects (lattice distortion). The various techniques used to quantify SSS and the role of different substitutional and interstitial elements/atoms in improving the strength of HEAs are outlined in detail. This review provides a good assessment on ways to enhance the mechanical properties of HEAs to suit the extreme demands of modern engineering applications. Based on theoretical modeling and experimental validation, Al and Nb provide superior substitutional SSS in face-centered cubic and body-centered cubic crystal structures, while carbon has a 50% more effect on improving the mechanical properties of HEAs than in stainless and twinning-induced plasticity steels. Moreover, a detailed description of the application of machine learning in design of HEAs shows that trial and error can eliminated in identifying HEAs with exceptional yield strength. The atomic size difference should be used to evaluate the lattice distortion effect.
Emotional and Psychological Impact of COVID-19 Induced Delay in Treatment of Medical Conditions
Authors: Kaur Harpreet , Kaundal Asmita
Published: September 2022

COVID-19 pandemic significantly affected the physical, social, economical and mental health globally. Social distancing, quarantine and national wide lockdowns became new norm. Hospital emergencies and were flooded with patients diagnosed with COVID-19, Intensive care units were full with critically ill COVID-19 patients. Most of the health care facilities were diverted towards the management of COVID 19 patients. Majority of the manpower were involved in the screening, diagnosing and management with those infected with COVID 19. There was no arrangements for non COVID patients which lead to delay in diagnosis of new onset disease and cancellation of the previously planned appointments of those with chronic disease. Delay in treatment resulted in increased anxiety, stress, fear and emotional and psychological disturbances in many.
Mouse Model of Irritant Contact Dermatitis
Authors: Malekpour Monireh , Etebari Atefe , Hezarosi Mahsa , Anissian Ali , Karimi Forouzan
Published: September 2022

Background: Irritant contact dermatitis is a common inflammatory skin disease characterized by skin barrier dysfunction, eczematous dermatitis, and chronic itching. This disease severely affects the quality of life. Considering that the current treatment approaches are not ideal, more extensive research is needed to develop new treatments. Mainly, a mouse model is needed to investigate the effectiveness of new drugs to treat this disease. Objectives: This study was conducted to create a mouse model of irritant contact dermatitis. Methods: In the current study, we used BALB/c female mice to prepare a mouse model of irritant contact dermatitis. To induce irritant contact dermatitis, we used a dinitrochlorobenzene mixture with acetone/olive oil as an irritant. After 10 days of application, the mouse skin tissue was isolated and examined in terms of histopathology. Results: The introduced protocol created an irritant contact dermatitis model clinically and histopathologically. Conclusions: In the present study, we introduced a new protocol using a mixture of dinitrochlorobenzene and acetone/olive oil to create an irritant contact dermatitis model. Mouse models have been extensively used to discover the complex mechanisms of irritant contact dermatitis and provide a preclinical platform before conducting clinical interventional research on humans to evaluate a new therapeutic approach. However, one should always look for models that cause the least pain and suffering in the animal and simultaneously are simple and reliable for the desired studies. Thus, our protocol is a new approach that can be effective and painless in creating a model of irritant contact dermatitis.
Cerebral Venous Reflux and Dilated Basal Ganglia Perivascular Space in Hypertensive Intracerebral Hemorrhage
Authors: Tsai Hsin-Hsi , Lee Bo-Ching , Chen Ya-Fang , Jeng Jiann-Shing , Tsai Li-Kai
Published: September 2022

Background and Purpose Cerebral venous flow alterations potentially contribute to age-related white matter changes, but their role in small vessel disease has not been investigated.Methods This study included 297 patients with hypertensive intracerebral hemorrhages (ICH) who underwent magnetic resonance imaging. Cerebral venous reflux (CVR) was defined as the presence of abnormal signal intensity in the dural venous sinuses or internal jugular vein on time-of-flight angiography. We investigated the association between CVR, dilated perivascular spaces (PVS), and recurrent stroke risk.Results CVR was observed in 38 (12.8%) patients. Compared to patients without CVR those with CVR were more likely to have high grade (>20 in the number) dilated PVS in the basal ganglia (60.5% vs. 35.1%; adjusted odds ratio [aOR], 2.64; 95% confidence interval [CI], 1.25 to 5.60; P=0.011) and large PVS (>3 mm in diameter) (50.0% vs. 18.5%; aOR, 3.87; 95% CI, 1.85 to 8.09; P<0.001). During a median follow-up of 18 months, patients with CVR had a higher recurrent stroke rate (13.6%/year vs. 6.2%/year; aOR, 2.53; 95% CI, 1.09 to 5.84; P=0.03) than those without CVR.Conclusions CVR may contribute to the formation of enlarged PVS and increase the risk of recurrent stroke in patients with hypertensive ICH.
Comparison of safety factor and geosyntetic reinforcement requirement for slope stability using 2-D and 3-D analysis method
Authors: Sari Putu , Lastiasih Yudhi , Shoffiana Nur
Published: September 2022

The analysis of landslide slope stability since 1960s is the development of a 2-D structure proposed by various experts, through the 3-D method. Most of these previous studies stated that the ratio of 3-D and 2-D safety factors was more than one for cohesive and less than one for non-cohesive soils. These were because several required slope reinforcements were affected by the safety factors, with the analytical differences of the 2-D and 3-D methods causing a distinction in the requirements. These differences further cause problems by underestimating or overestimating the design. Therefore, this study aims to determine a comparative analysis of 2-D and 3-D slope stability on several required reinforcements. The analyses of the 2-D and 3-D structures were carried out using the LEM proposed by Fellenius and Hovland, respectively. The comparison of the several required reinforcements was also conducted using geotextile with Tult = 200 kN/m. The results showed that the reinforcements required with geotextile between 2-D and 3-D analysis were relatively similar on homogeneous soils. Meanwhile, the geotextile reinforcement needs were different for heterogeneous soils. Under different certain conditions, the need for 2-D reinforcement was greater and lesser than 3-D. In addition, the difference in the reinforcement required for the analysis of these structures was between 1-8 layers of geotextile, depending on soil parameters, slope, and length of the landslide field.
Social and lifestyle characteristics of sports bettors in Serbia
Authors: Todorović Jovana , Terzić-Supić Zorica , Kilibarda Biljana , Mravčik Viktor , Stanisavljević Dejana , Stanisavljević Tamara , Piperac Pavle , Gojnić Miroslava , Dugalić Stefan
Published: September 2022

Aim: The aim of our study was to examine the prevalence of sports betting in the previous month in Serbia and its association with social and lifestyle characteristics. Methods: The analysis of the data from the cross-sectional survey National Survey on lifestyles in Serbia: substance abuse and gambling conducted in 2014 was performed. 10% of participants reported sports betting in the past 30 days. Results: Sports betting was associated with male gender, living in urban areas compared to living in rural areas, having secondary education compared to having primary education, being employed compared to being retired. Sports betting in the previous month was also associated with binge-drinking compared to abstaining from alcohol, non-prescription use of anti-anxiety medications compared to no use of anti-anxiety medications and low/ moderate problem gambling compared to no problem gambling as measured by PGSI. However, it was not associated with a higher risk of tobacco smoking and illicit drug use. Conclusions: The association of sports betting with risk behaviors among young males should be a concern for public health authorities.
The role of active perinatology in the prevention of spontaneous loss of conceptus and birth rate drop
Authors: Dugalić Stefan , Stanisavljević Dejana , Petronijević Miloš , Stefanović Aleksandar , Vrzić-Petronijević Svetlana , Stefanović Katarina , Gutić-Vukobrat Bojana , Gojnić Miroslava , Macura Maja , Božić Dragana , Stanisavljević Tamara , Petronijević Milica , Todorović Jovana
Published: September 2022

Introduction: Modern perinatology demands continuous improvement of doctrines and protocols. The loss of conceptus is unforgivable when the possibility to sustain such pregnancy would elevate the level of birth rate that we aspire as a society. The aim of this study was to show the role of low molecular weight heparin in prevention of poor pregnancy outcomes. Methods: The study included all women with inherited thrombophilia referred to the Clinic for Gynecology and Obstetrics of the Clinical Centre of Serbia between 2016 and 2018 who were followed-up until delivery. The patients were divided into two groups. Results: The total number of 180 patients were pregnant for the first time, while 178 patients had had previous pregnancies. In 153 out of 178 patients, the previous pregnancy had poor outcome. 12 patients with AC therapy had FMU in previous pregnancies, 49 patients had missed abortion, 54 patients had second trimester miscarriage, 4 patients had both FMU and missed abortion, 9 patients had missed abortion and second trimester miscarriage while one patient had FMU, missed abortion and second trimester miscarriage. In previous pregnancies, 92 babies were born out of 313 pregnancies while in the current pregnancies treated with therapy there were 173 babies from 151 pregnancies. Conclusions: Patients with anticoagulant treatment in current pregnancy have had significant burden of previous pregnancy losses.
Multivariate logistic model of hospital length of stay after appendectomy
Authors: Doklestić Krstina , Lončar Zlatibor , Bukumirić Zoran
Published: September 2022

Background: Appendectomies are interesting because they are the most common emergency abdominal operations, they are considered simple procedures, and the imperative is a quick recovery measured by hospital length of stay (LOS). However, this is not always the case in clinical practice, hospitalization can be prolonged, and the question is what factors affect it. Methods: A multivariant logistic model of LOS predictors analyzed from the clinical data of 446 patients who underwent appendectomy at the Clinic for Emergency Surgery, Belgrade. The patients were divided into Short LOS group (SLOS hospital stay ≤3 days, 157 patients) and Long LOS group (LLOS hospital stay >3 days, 289 patients). Results: Significant differences were found between SLOS and LLOS groups in age (p<0.001), comorbidities (p=0.001), preoperative WBC (p = 0.004); preoperative CRP (p < 0.001); peritonitis (p < 0.001), using ≥ 2 antibiotics (p < 0.001), complicated appendicitis (p < 0.001), surgical time (P < 0.001). No significant difference was found concerning gender, postoperative WBC, CRP, and complications (p>0.05). Patients who underwent laparoscopic appendectomy (LAP) had a statistically significantly shorter hospitalization time compared to those who underwent Mini-Incision Open Appendectomy (MIOA) (p < 0.001). The multivariate logistic model found three statistically significant predictors of longer hospitalization: CRP preoperatively (B=0.006, p=0.047), OR=1.006, the type of surgery (B=1.199; p<0.001), OR=3.3 complicated appendicitis (B=0.762; p=0.003), OR=2.142. Conclusion: Surgical approach has statistically the most significant impact on LOS. Laparoscopic appendectomy is superior to Mini-Incision Open Appendectomy concerning the hospital LOS.
BK polyomavirus as the cause of hemorrhagic cystitis in patients treated with allogeneic stem cell transplantation
Authors: Stanković Stefan , Đunić Irena
Published: September 2022

Introduction: BK polyomavirus is a double-stranded DNA virus from the Polyomaviridae family. According to DNA sequences, this virus can be classified into six genotypes. In hematological patients enrolled in allogeneic hematopoietic stem cell transplantation (HSCT) programs, it can lead to hemorrhagic cystitis. Aim: The aim of this study is calculating the prevalence of BK polyomavirus PCR (polymerase chain reaction) positivity in the blood and urine of patients involved in allogeneic HSCT, determining the predictive factors for clinical presentation of BK polyomavirus-associated hemorrhagic cystitis, as well as determining its effects on overall survival (OS) of the patients. Materials and methods: This retrospective cohort study enrolled 42 patients from the Clinic of Hematology of the University Clinical Center of Serbia. The presence of the virus in blood and urine was determined by the PCR method. The survival rate of the patients in relation to hemorrhagic cystitis was calculated with the Kaplan-Meier method and comparison was performed with the log-rank test. Results: A positive PCR result in the blood was found in 97.6% of the subjects, while urine tested positive in 100% of patients. The estimated survival time in patients without hemorrhagic cystitis was 44.357 months, while the group with the clinical presentation of hemorrhagic cystitis had an estimated survival time of 17.395 months. Based on the log-rank test, we found a significant difference in survival between those groups of patients (p = 0.049). With regards to leukocyte engraftment day, patients engrafted after D+14, had a higher frequency of hemorrhagic cystitis (p = 0.037). Conclusion: BK polyomavirus-associated hemorrhagic cystitis is a common complication of treatment in patients suffering from hematological malignancies who are enrolled in an alo-HSCT program, and has a significant impact on OS..
Violin plots as visual tools in the meta-analysis of Single-Case Experimental Designs
Authors: Tanious René , Manolov Rumen
Published: September 2022

Despite the existence of sophisticated statistical methods, systematic reviews regularly indicate that single-case experimental designs (SCEDs) are predominantly analyzed through visual tools. For the quantitative aggregation of results, different meta-analytical techniques are available, but specific visual tools for the meta-analysis of SCEDs are lacking. The present article therefore describes the use of violin plots as visual tools to represent the raw data. We first describe the underlying rationale of violin plots and their main characteristics. We then show how the violin plots can complement the statistics obtained in a quantitative meta-analysis. The main advantages of violin plots as visual tools in meta-analysis are (a) that they preserve information about the raw data from each study, (b) that they have the ability to visually represent data from different designs in one graph, and (c) that they enable the comparison of score distributions from different experimental phases from different studies.
How to define and test an indirect moderation model: The missing link in regression-based path models
Authors: van Kollenburg Geert H. , Croon Marcel A.
Published: September 2022

Two of the most important extensions of the basic regression model are moderated effects (due to interactions) and mediated effects (i.e. indirect effects). Combinations of these effects may also be present. In this work, an important, yet missing combination is presented that can determine whether a moderating effect itself is mediated by another variable. This ‘indirect moderation’ model can be assessed by a four-step decision tree which guides the user through the necessary regression analyses to infer or refute indirect moderation. A simulation experiment shows how the method works under some basic scenarios.
Evaluation of the Effect of Non-Surgical Periodontal Treatment on Oral Health-Related Quality of Life in Patients with Periodontitis at Different Stages
Authors: TAYMAN Mahmure Ayşe
Published: September 2022

Aim: To determine the effect of non-surgical periodontal treatment (NSPT) on oral health-related-quality-of-life (OHRQoL) in individuals with periodontitis at different stages.
Materials and Methods: Full-mouth clinical periodontal parameters [plaque-index (PI), gingival-index (GI), probing-pocket-depth (PD), bleeding-on-probing (BOP), clinical-attachment-loss (CAL)] of 119 healthy individuals aged 24 to 64 years just before and six-weeks after NSPT were obtained and the mean was calculated. Oral hygiene instructions were given. The Oral-Health-Related-Quality-of-Life-United-Kingdom (OHRQoL-UK) scale was used to measure the positive and negative effects of NSPT on OHRQoL. Sociodemographic data (age, gender, education and income status, reason for admission to the hospital, use of toothbrush, other cleaning tools, removable prosthesis and smoking) of the participants were recorded using a multiple choice questionnaire.
Results: The use of toothbrushes and cleaning device increased in all phases after the treatment (p<0.01). Ages of individuals in stage-IV were higher than other stages (p>0.05). Individuals in stage-III (p=0.01) and IV had fewer teeth than other stages (p=0.01), while the use of removable prosthesis was higher (p<0.05). Clinical periodontal parameters decreased significantly in all stages after treatment and showed improvement (p<0.01). When all stages before and after treatment were compared within themselves, there were significant differences in the total score of OHRQoL between stages I-III, I-IV, II-III and II-IV (p<0.05). It was observed that all OHRQoL scores increased when compared before and after treatment in terms of symptoms, physical, psychological and social status (p<0.01).
Conclusion: NSPT provides a significant improvement in the OHRQoL of individuals in all stages of periodontitis.
In the Face of Uncertainty, Peer-Training: Lessons from a Group Strategy Undertaken by Sociology Faculty During the Pandemic
Authors: Castillo-Eslava Francisco , Moldes-Anaya Sergio , Fuster Nayla , Sánchez Mariano , García de Diego Jose María , Baldán Henar
Published: September 2022

The training offered to university teaching staff tends to be scant, voluntary and heavily oriented toward novice teachers. With the arrival of Covid-19 and the sudden switch to online teaching, training became an urgent need for teachers. In this context, some faculty members of the University of *anonimizado* created a multi-cohort faculty peer-training group for collaborative learning in multimodal teaching methods. This paper describes the initiative and analyses the impact of the training on participating faculty members. The authors used a mixed methods research strategy with a sequential approach. Results indicate that training action’s collaborative dynamics contributed to the general well-being of the participants, bringing about a reduction in their feelings of isolation, insecurity and lessening their perception that they lacked the skills required for the new situation. Also, intergenerational differences were detected in the effects the training had on more novice and more experienced teachers.
Latin Kare Tasarımı ile Farklı Sektörlerdeki İş Kazalarının Analizi
Authors: ÇİÇEK Fatma , ATA Ayça , ÖVEZ Bikem
Published: September 2022

Dünya nüfusundaki artış ile doğru orantılı olarak artan üretim, ekonomik büyüme ve teknolojik gelişmeler ile petrol, kömür, doğal gaz, nükleer, hidrolik gibi gerek fosil gerekse yenilenebilir enerji kaynaklarına olan talep de artmaktadır. Kömür rezerv değerleri göz önüne alındığında, global olarak kömür üretim ve tüketimine yönelik teknolojik gelişmelerin devam edeceği öngörülmektedir. Türkiye için de, sera gazı salınımları doğrultusunda alınan önlemlere göre kömüre dayalı elektrik üretimi azalım gösterse de, dünya genelindeki enerji arz paylarındaki artış ile trende uyum göstermesi beklenmektedir. Ülkemizdeki ekonomik yeri ve üretim sürecinin doğası gereği en riskli iş kollarından biri madencilik sektörüdür. Avrupa bazında, bu sektörde yaşanan can kayıplarının %59’unun Türkiye’de olduğu görülmüştür.

Bu çalışmada, 17 farklı Avrupa ülkesi için ILOSTAT verileri ile tarım, üretim, inşaat, maden ve diğer sektörlerde 2009 – 2019 yıllarında meydana gelen iş kazalarında yaşanan can kayıpları incelenmiştir. Tarım dışında tüm sektörlerde Türkiye en çok kayıp veren ülke olmuştur.

İş kazası riski göz önünde tutularak kömür üretimine sahip ve madencilik sektöründe en çok kayıp veren Türkiye, Almanya, Çek Cumhuriyeti, ve Polonya verileri Latin Kare Tasarım deneysel düzeninde, yıl, ülke ve sektör değişkenleri ile Genel Doğrusal Model ile istatistiksel olarak incelenmiştir. ANOVA analizi ile her değişkenin tekil ve ikili etkileşimleri (p
İşte Var Olmama (Presenteeism) ve İş Tatmini İlişkisinde Örgütsel Sinizmin Aracılık Rolü ve Yaş Faktörü
Authors: KARADAĞ Turabi
Published: September 2022

Bu araştırma iş sağlığı güvenliği uzmanlarının iş tatmin düzeyi üzerinde işte var olamama algısının etkisi ve bu etkiye aracılık eden veya düzenleyen örgütsel sinizm ve yaş faktörlerinin ilişkisine ışık tutmak amacıyla gerçekleştirilmiştir. Araştırma problemini nicel yöntemlerle irdeleyebilmek için veriler, internet üzerinden uygulanan anket formu ile 251 iş sağlığı güvenliği uzmanından veri toplanmıştır. En küçük kareler yöntemine dayalı iki regresyon modeli kurulmuştur. İlk regresyon modelinde işte var olamama algısı düzeyinin iş tatmini üzerindeki doğrudan etkisi, örgütsel sinizm düzeyinin doğrudan etkisi ve aracılık etkisi incelenmiştir. İkinci regresyon modelinde ise yaş faktörünün bu etkiler üzerindeki yönetici/ düzenleyici etkisi sorgulanmıştır. İşte var olamama algısının iş tatmini üzerindeki tek başına etkisi istatistiksel açıdan anlamlı değilken, örgütsel sinizm faktörünün aracılık etkisiyle birlikte Presenteeism algısının iş tatmini üzerindeki etkisi anlamlıdır. Dolayısıyla örgütsel sinizm tam aracılık etkisine sahiptir. İki değişkendeki değişimin iş tatmin düzeyi üzerindeki etkisi negatiftir. Yaş faktörünün bu ilişki örüntüsündeki yönetici etkisi anlamlıdır. Ancak yaşın yöneticilik etkisi presenteeism düzeyinin tek başına etkisi üzerinde değil, Örgütsel sinizm faktörü ve onun aracılık etkisi üzerinde anlamlıdır. Yaş artıkça, presenteeismin sinizm aracılığıyla iş tatmini üzerindeki etkisi artma eğilimindedir.
Demand Forecasting with Integration of Time Series and Regression Models in Pharmaceutical Industry
Authors: İMECE Salih , BEYCA Ömer Faruk
Published: September 2022

Accurate demand forecasting is crucially important to reduce inventory and backlogging cost. In this study, we analyze howpromos, holiday statements, price changes, stock availability and date-time features (weekdays, months etc.) affect thedemand by using several forecasting methods. Data sets were collected for the products of the global pharmaceuticalcompany providing services in Turkey. Actual daily sales data for 2016, 2017 and 2018 were used in the construction of thisdata set. In order to predict the next periods demand, we used four different models which are Holt Winters, RidgeRegression, Random Forest and Xgboost. We also ensemble those models to improve forecasting accuracy. Next, byweighting inversely proportional to the error rates of the models, binary, triple and quadruple combinations of the singlemodels were compared with themselves and the single models. Our numerical results show that the lowest forecasting errorrate was obtained in ensemble models. Particularly, the lowest error rate in individual models was obtained in Random Forestwith 15.7% RMSPE (Root Mean Square Percentage Error) value, and the lowest error rate was obtained with 10.7% RMSPEvalue in Holt Winters & Xgboost models combination. Results show that ensemble of several models can increase theforecasting accuracy.
Comparison of Different Cooling Systems in Plastic Injection Molding
Authors: GİRİT Oğuz
Published: September 2022

Injection molding is preferred for plastic products due to its high efficiency. However, one of the most important factors after injection is the cooling of the part. Therefore, the cooling process considers being an essential part of the total molding time. Generally, the cooling process in plastic injection molds is done by circulating the cooling liquid through the holes opened in the radial and axial direction on the mold. However, in cases where the cooling is not at the wanted level, the efficiency is increased by placing high thermal conductivity coefficients materials in the molds. With the development of manufacturing methods, conformal cooling systems with cooling channels that follow the molded part geometry have emerged as an alternative to this method. However, this is an expensive method, and studies are ongoing. In this study, the mold cooling times were analyzed and compared with the help of the MoldFlow analysis program on a sample part with a conventional cooling system, as a result of placing a conformal cooling system and a material (insert) with a high thermal conductivity coefficient in the mold.