bluuebunny/crossref_metadata_2025 huggingface dataset:
AN ANALYSIS OF DAVID AND EMILY CALLAWAY’S PSYCHOPATH PROBLEMS IN HIDE AND SEEK MOVIE VIEWED FROM SIGMUND FREUD’S PSYCHOANALYSIS THEORY
Authors: Fuady Dean Rahmat , Suhendar Suhendar
Published: December 2019

This research aims to analyze the main characters in Hide and Seek movie as the characters who have psychopathic problem and Dissociative Identity Disorder. In relation to which, the writer studied Hide and Seek movie as the unit of analysis. Psychopathic problems viewed from Sigmund Freud’s psychoanalysis concepts are used for the review of related literature theories or concepts of the research. Therefore, the method of the research is descriptive qualitative, which tries to explain about the intrinsic elements of the movie; such as characterization and the scenes of the movie, then followed by analyzing them through Sigmund Freud’s psychoanalysis. Through observations of the scenes and the behavior of the main characters the writer reveals David and Emily have been identified to have psychopathic characters such as manipulative, parasitical, deceitful, power hungry, less empathy, often lie, shallow affect and poor behavioral control. In addition, the causes of such character are trauma and stress viewed from Sigmund Freud’s psychoanalysis theory
POST-TRAUMATIC STRESS DISORDER OF THE MAIN CHARACTER IN “WILD” MOVIE DIRECTED BY JEAN-MARC VALLEE
Authors: Sutrisno Bejo , Yuliana Ernissa
Published: December 2019

The objectives of this research are to describe Post-Traumatic Stress Disorder be shown of the main character and to mention the types of Post-Traumatic Stress Disorder that the main character suffers. In this movie, it shows about Post-Traumatic Stress Disorder Of The Main Character. The movie cuts out a few important people in Cheryl’s real life. In the movie, Cheryl has only one sibling, her younger brother Leif. Cheryl and her father grew particularly close during her mother’s sickness, but after she passed, Eddie remarried and grew distant. Much of Cheryl’s internal monologue during her therapy sessions is made into dialogue with her therapist in the movie. In this movie also explains how to eliminate trauma, by climbing many obstacles by oneself, through many obstacles, so Cheryl feels very grateful for the present life and he realizes that what he does in front must he face, she can not escape from the problem is, because it is history and the future is a mystery that must be dealt with better.
Dossier: tecnologías poéticas en el arte contemporáneo
Authors: Navallo Tatiana , Ulm Hernán
Published: December 2019

El dossier indaga en torno a las configuraciones de lo sensible en el mundo contemporáneo. La percepeción del mundo y de nosotros mismos no es natural, neutra o pura. Siempre está construida a partir de unconjunto de reglas que definen lo que llamamos un “ritual de la percepción”. En este sentido, los agenciamientos sociales son, en primer lugar, agenciamientos de lo sensible. Las reglas que operan en la configuración de la sensibilidad pueden tener dos devenires: un devenir técnico y otro artístico. A partir del siglo XX, el agenciamiento de producción de sensibilidad opera a través bioinformatización, mediante cálculos algorítmico digitales. Los textos que se presentan a continuación intentan una reflexión crítica que pone de relieve los alcances de esta mutación, tomando como eje conductor la cuestión del arte.
¿Cómo salir de la literatura? Literatura y arte contemporáneo
Authors: Gutiérrez Rafael
Published: December 2019

A partir de la experiencia y de algunas obras de escritores y artistas este ensayo busca una aproximación a las relaciones de doble vía entre la literatura y el arte contemporáneo. Por un lado, intento describir y analizar la forma en que diversas obras artísticas contemporáneas como las de Dominique González-Foerster, Tim Youd o Kenneth Goldsmith, se relacionan o se apropian de la literatura; por otro lado, busco comprender la forma en que estrategias, técnicas y concepciones de las artes de las últimas décadas son también apropiadas por escritores y escritoras contemporáneas como César Aira, Angélica Freitas, Mario Bellatin, Marcelo Bene o Enrique Vila-Matas. Intento pensar esta problemática en el marco de la tradición comparatista que busca establecer semejanzas o puntos en común entre diversas expresiones y modalidades artísticas.
KELAS REMAJA ( PERSIAPAN PRA NIKAH ) UPAYA PEMBENTUKAN GENERASI BERENCANA DI KELURAHAN CIKALANG
Authors: Patimah Siti , Mulyani Nunung , Silalahi Uly Artha
Published: December 2019

Remaja dihadapkan dengan masa sulit dalam perkembangan baik secara mental, sosial dan kultural. Remaja terbatas aksesnya untuk mendapatkan pelayanan dan informasi yang benar. Riset Kesehatan Dasar (Riskesdas) 2010 memaparkan data pernikahan dini dan eksperimentasi seksual pada usia dini,  perempuan muda di Indonesia dengan usia 10-14 tahun menikah pada tahun 2010 sebanyak 0.2 persen. Perempuan muda berusia 15-19 yang menikah lebih besar jika dibandingkan dengan laki-laki muda berusia 15-19 tahun, yaitu 11,7 persen dibandingkan dengan 1,6 persen. Pelaksanaan pengabdian masyarakat ini dilaksanakan melalui metode pendidikan kesehatan dan pelatihan dari Tim  dan mitra yaitu BKKBN. Adapun yang menjadi sasaran dalam kegiatan ini adalah para remaja umur 14-19 tahun, kelompok pengajian pemuda, remaja karang taruna di Kelurahan Cikalang Kecamatan Tawang Kota Tasikmalaya. Hasil kegiatan pengabmasy ini diperoleh peningkatan yang signifikan pengetahuan remaja sebelum dan sesudah mengikuti kelas remaja sebesar 88 %. Mubarak (2011) menyebutkan bahwa Pengetahuan seseorang sangat dipengaruhi oleh faktor pendidikan, pekerjaan, umur, minat, pengalaman, dan informasi. Dengan mengikuti kelas remaja mendapatkan informasi tentang kesehatan reproduksi remaja dan persiapan pranikah, karenanya maka terdapat peningkatan pengetahuan remaja. Selain kegiatan kelas remaja juga dilakukan pelayanan kesehatan berupa pemeriksaan Hb. Hal ini dilakukan karena sebagian besar remaja banyak yang mengalami anemia. Hasil pemeriksaan menemukan sebanyak 11 dari 17 (65%) remaja putri menderita anemia. Hasil lainnya berupa tersusunnya modul dan pemebentukan PIK – R di Kelurahan Cikalang.
PELATIHAN MANAJEMEN PEMASARAN KREATIF INDUSTRIAL DI BIDANG KESEHATAN GIGI DI MASYARAKAT
Authors: Nugroho Cahyo , Miko Hadiyat , Samjaji Samjaji
Published: December 2019

Pemasaran adalah salah satu hal yang penting dalam elemen produksi, begitu jugadalam konteks industri kreatif yang sedang digalakan oleh pemerintah saat ini terutama bagimasyarakat. Program perlindungan yang dibentuk oleh pemerintah bagi keluarga kurangmampu adalah Program Keluarga Harapan (PKH) yang bertujuan untuk membantu memenuhikebutuhan pendidikan dan kesehatan dan memberikan kemampuan kepada seluruh keluargauntuk memenuhi kebutuhan konsumsi. Sebagian besar masyarakat di wilayah RW 15 dan RW16 Kelurahan Kersamenak Kecamatan Mangkubumi bermata pencaharian pegawai lepas.Pada masyarakat di kedua RW tersebut diantaranya ada yang termasuk pada kelompokProgram Keluarga Harapan (PKH) berjumlah ± 25 Kepala Keluarga.Kelompok ini perlumendapatkan dukungan pemerintah dan masyarakat. Tujuan Pengabdian Masyarakat iniadalah meningkatkan derajat kesehatan gigi dan mulut serta membentuk/mengembangkansekelompok masyarakat yang mandiri secara ekonomi. Metode pelaksanaan pada programpengabdian masyarakat ini yaitu dengan memberikan pelatihan manajemen pemasaran kepadakelompok Program Keluarga Harapan.Kegiatan ini dilaksanakan oleh 1 orang professionalterkait dan 3 (tiga) tenaga kesehatan gigi yang dibantu oleh kader di wilayah setempat.
Dental Anxiety and Fear: What are the Best Evidence Based Measure to Avoid it?
Authors: Ahmed Siddiqui Ammar
Published: December 2019

Fear to dental drill and fill is common and widespread throughout the world population. It affects quite a large population of all ages all over the globe. Many patients go untreated because anxiety or stress is commonly associated with dental settings [1]. Special needs people, such as pregnant mothers, old people or disabled children are much affected. The question arises is what has been done scientifically to reduce the negative impact associated with dental anxiety? How successful we are in controlling it? What are the most productive ways to enhance patient’s confidence against it? The severity of anxiety may vary among people
Intralesional Steroid Treatment of Aggressive Central Giant Cell Granuloma of the Mandible
Authors: H. Al-Bodbaij Mohammed
Published: December 2019

Central giant cell granuloma (CGCG) is a non-neoplastic lesion that affects children and young adults. Various treatment modalities have been suggested for CGCG. The most commonly applied is surgery with possible variable recurrence rates. Other treatment modalities such as calcitonin and intralesional steroid have been used with good results.

In the current case report, a 14-year old boy presented with an aggressive CGCG of the mandible that had been treated with six weekly intralesional injections of steroids that provided very good results.
Predictability of Modified Miller’s Classification in Assessing the Treatment Outcomes of Gingival Recession Defects-A Case Series
Authors: Mahajan Ajay
Published: December 2019

Despite its limitations and drawbacks the Miller’s classification system continues to be the most popular system for classifying gingival recession defects (GRDs), however, recent studies have challenged the use of Miller’s classification system and many new classification systems have been proposed. Mahajan’s classification system is a modification of Miller’s classification and has been found to be reliable in identifying GRD. Since predicting the pathogenesis and prognosis of the disease process in GRDs is an essential requirement for a valid classification system and till date no study is available in the literature which assesses the predictive capacity of the modified Millers classification, the present study was done to evaluate the same. A total of 21 GRDs were classified according to the modified Miller’s classification and were treated subsequently. At the end of the study the modified Miller’s classification system was found to have satisfactory predictive value and the post operative results correlated well with the pre-treatment prognosis for various recession classes.
The Link between Fingerprints, Genetics & Chronic Periodontitis: A Dermatoglyphic Study
Authors: Karthikeyan S.S.Sai
Published: December 2019

Background: Several methods have been employed for diagnosing inflammatory conditions including biomarkers, enzymes and various other clinical parameters. Dermatoglyphics is one such field which has gained entry in Forensic Medicine, Forensic Odontology and in General Medicine for diagnosing chronic inflammatory conditions. Periodontitis is a chronic inflammatory condition associated with destruction of periodontal tissues. This study aimed to assess the relationship between the fingerprint patterns and chronic periodontitis

Methods: A total of 60 patients, belonging to both healthy and chronic periodontitis subjects were assessed by a commercially available fingerprint scanner. All the fingerprint images were assessed for the fingerprint pattern and the ridge count manually. The results were tabulated as percentage frequency distribution for the type of fingerprint pattern. The ridge count is shown as mean ± SD. Unpaired t test was applied to test for statistical significance.

Results: The frequency distribution showed equal percentage of Radial Loop type of fingerprint pattern in subjects of both Health and Chronic Periodontitis. Statistical analysis showed Plain Whorl type of fingerprint pattern more significant in subjects having Chronic Periodontitis

Conclusion: It was concluded that there might be a relationship between type of fingerprint pattern to the chances of a person having Chronic Periodontitis.
HBOT Application at Cases of Gingival Inflammation
Authors: Robo Ilma
Published: December 2019

The treatment of periodontal diseases, mainly of their origin, with the most common clinical manifestation in form of gingival inflammation, is manifold and powerful, including: mechanical therapy, antibiotic, antiseptic and various approaches to treatment, which are recommended to be used within a short period of time. New therapeutic approaches have been proven as alternative treatment to conventional therapy, or in combination with conventional therapies, to reduce the number of periodontopathic pathogens in gingival sulcus.

HBOT has a detrimental effect on periodontal microorganisms, as well as beneficial effects on the healing of periodontal tissue, increasing oxygen pressure in gingival pockets. Our study is aimed at reviewing the current published literature on hyperbaric oxygen therapy and focuses on role of HBOT as a therapeutic measure for the individual with periodontal disease in general and for the impact on the recovery of gingival inflammation.

HBOT and periodontal treatment together, reduce up to 99% of the gram-negative anaerobic load of subgingival flora. HBOT, significantly reduces subgingival anaerobic flora. Clinical effects in 2-year follow-up of treated patients are sensitive. Reduction of gingival hemorrhage indexes, depth of peritoneum, plaque index, occurs in cases of combination of HBOT and detraction. Reduced load persists up to 2 months after therapy. The significant increase in connective tissue removal starts at the end of 2nd week, to achieve the maximum in week 3-6 of application. HBOT used for re-implantation, stimulates the healing of periodontal membrane, pulp, prevents root resorption, healing of periodontal lining tissues. HBOT, significantly reduces the hemorrhage index with 1.2 value difference, 0.7mm probe depth, reduces gingival fluid by 2. HGH exposure is increased by gingival blood flow, with a difference of 2 in measured value. The therapeutic effects of HBOT in the value of the evaluation index can be saved up to 1-year post treatment.
Comparing the Genetic Detox Ability and Heavy Metal Burden in a Cohort of Samples of Egyptian Children and those with Autistic Spectrum Disorder
Authors: E Blaurock-Busch
Published: December 2019

The heavy metal burden of patients with Autism spectrum disorders (ASD) has been widely discussed [1-5]. Present knowledge suggests that ASD patients, compared to ‘normal’s’ show a greater metal burden, which may be a cause of the ASD pathogenesis, possibly due to a limited detoxification potential. We thus aimed to evaluate if the metal burden of ASD children is due to comprised detoxification ability, and if missing of enzymes such as the glutathione-S-transferases provide an explanation, or if additional factors play a role. Genetically, we noticed a slight difference in the detoxification ability of the ASD group compared to the Control group. In the ASD group, carrier of the genotype GSTT1 null genotype (i.e. the homozygous loss) are 1.7 times more common as in the Control group and the GSTT1 allele is more frequent in the ASD patient collective. These findings are not statistically significant but indicate a trend. In addition, our data indicates that levels of potentially toxic metals in blood and hair of both groups demonstrate a similar immediate and long-term exposure. However, 36% of the ASD group showed signs of zinc deficiency compared to 11% of the Control group and this points towards inefficiency of the Phase I detoxification pathway. More research is needed to explore the role of other elements in the detoxification pathway.
Rares Diseases and Handicap: State of the Medical, Social and Health Policy in Developing Countries. Cameroon case: about One Case: Cushing Disease
Authors: Kpoumie Carolle Laure
Published: December 2019

Rare’s diseases and orphan’s diseases, disability (orhandicap) are a reality throughout the world and a real public health problem in developing countries. The great precariousness in which the populations live increases their impact and their gravity by the absence of information, technical platform, means of detection, actual presence of research and clinical studies on these territories, lack of awareness of the detection, diagnosis, without forgetting that the means of care and prevention are sometimes in existent or little known and especially expensive in countries where the populations are poor, without mutual or social security as in industrialized countries .This work will focus on a patient case presenting a rare disease: Cushing's disease. A case that occurred in Cameroon in order to establish in a practical way this major and yet ignored, neglected issue in a health system with poor specialized structures, technical platforms, and without the support of the pharmaceutical laboratories that could with the health system of these poor countries set up a system of refueling in the sense of the social view the cost that requires the monitoring of these long pathologies that make autonomous living almost impossible, also life-threatening.In Cameroon, there have been difficulties in the care and monitoring of this young patient since childhood through the phase of the pubertal transition, adolescence, to adulthood. It is therefore important to organize the follow-up of these patients, by developing specific programs of medical follow-up, psychological care, and social integration programs. Health policies should invest in better support.
Diploma course: “The Social Smoking Cost in the National Economy”; A Necessary and Apply-able Tool
Authors: Hernandez Fe Fernandez
Published: December 2019

Objective: Create a diploma course about the smoking economic control.

Introduction:The smoking economic control is a prioritized strategic for the diminution of tobacco and cigarettes consumption. In the real Cuban context, it evidences insufficient knowledge in economic subject by Public Health workers´ especially from the health workers related with the smoking control actions. In consequence it is necessary to apply to the Superior Medical Education to contribute to a better professional education for the human resources related directly with the smoking control.

Material and methods: The theatricals methods used were the analysis and synthesis, the comparative and the inductive deductive. Like empiric method was used the bibliographic research.

Results: The diploma course “The smoking´s social costs” is an answer from the necessity to improve the postgraduate formation from human resources hardly committed with the smoking control. This course explains smoking since a socioeconomic point of view with special emphasis in the social costs attributable to this risk factor. By itself the diploma course introduces an integral view of the smoking control and should be interesting for economists and accountants too.

Conclusion: The diploma course takes account the particularities from the health sector respect to the postgraduate education necessities´ about the smoking economic control. Also, the diploma structure is according to the regulations established for it.
Crossroad of Molecular Networks and Disease Treatment
Authors: Tanabe Shihori
Published: December 2019

Various molecular networks including both canonical and non-canonical pathways are activated in cancer. It has some rationales to target the molecular network pathways to treat cancer, considering that the pathway regulation including immune pathways is important for cancer progression. The molecular pathways targeted by several anti-cancer drugs are focused in this article to investigate the networks consisting of molecular pathways related to cancer formation.
BUBBLES OR CYCLES? HOUSING PRICE DYNAMICS IN CHINA’S MAJOR CITIES
Authors: Li Jing , Wei Yigang , Chiang Yat Hung
Published: December 2019

Based on the monthly data of 35 cities during the period 2006−2017, this study adopts a recursive forward looking method to detect the presence of housing bubbles and investigate their potential cyclical patterns in China’s large and medium sized cities. Empirical results show that the number of cities reporting housing bubbles has been increasing since 2013, before it declined in 2017. Regarding regional disparities of housing bubbles, 1st-tier and 1.5-tier cities have higher probability than 2nd-tier cities for housing bubbles. In general, eastern region cities have more housing bubbles than central and western region cities, which may indicate the problem of shrinking cities China is facing nowadays. Bubble signals for market correction in major cities and municipalities seemed alarming in particular for the period 2013−2016, however it is difficult to conclude if the market adjustment in 2017 indicates a cyclical pattern.
The Complex Rotational Light Curve of (385446) Manwë–Thorondor, a Multicomponent Eclipsing System in the Kuiper Belt
Authors: Rabinowitz David L. , Benecchi Susan D. , Grundy William M. , Verbiscer Anne J. , Thirouin Audrey
Published: December 2019

Kuiper Belt Object (385446) Manwë–Thorondor is a multiobject system with mutual events predicted to occur from 2014 to 2019. To detect the events, we observed the system at 4 epochs (UT 2016 August 25 and 26, 2017 July 22 and 25, 2017 November 9, and 2018 October 6) in g, r, and VR bands using the 4 m SOAR and the 8.1 m Gemini South telescopes at Cerro Pachón, Chile, and Lowell Observatory’s 4.3 m Discovery Channel Telescope at Happy Jack, Arizona. These dates overlap the uncertainty range (±0.5 day) for four inferior events (Thorondor eclipsing Manwë). We clearly observe variability for the unresolved system with a double-peaked period 11.88190 ± 0.00005 hr and ∼0.5 mag amplitude together with much longer-term variability. Using a multicomponent model, we simultaneously fit our observations and earlier photometry measured separately for Manwë and Thorondor with the Hubble Space Telescope. Our fit suggests Manwë is bilobed, close to the “barbell” shape expected for a strengthless body with density ∼0.8 g cm−3 in hydrostatic equilibrium. For Manwë, we thereby derive maximum width to length ratio ∼0.30, surface area equivalent to a sphere of diameter 190 km, geometric albedo 0.06, mass 1.4 × 1018 kg, and spin axis oriented ∼75° from Earth’s line of sight. Changes in Thorondor’s brightness by ∼0.6 mag with a ∼300 day period may account for the system’s long-term variability. Mutual events with unexpectedly shallow depth and short duration may account for residuals to the fit. The system is complex, providing a challenging puzzle for future modeling efforts.
The Full Kepler Phase Curve of the Eclipsing Hot White Dwarf Binary System KOI-964
Authors: Wong Ian , Shporer Avi , Becker Juliette C. , Fulton Benjamin J. , Berger Travis A. , Weinberg Nevin N. , Arras Phil , Howard Andrew W. , Benneke Björn
Published: December 2019

We analyze the full Kepler phase curve of KOI-964, a binary system consisting of a hot white dwarf on an eclipsing orbit around an A-type host star. Using all 18 quarters of long-cadence photometry, we carry out a joint light-curve fit and obtain improved phase-curve amplitudes, occultation depths, orbital parameters, and transit ephemeris over the previous results of Carter et al. A periodogram of the residuals from the phase-curve fit reveals an additional stellar variability signal from the host star with a characteristic period of 0.620276 ± 0.000011 days and a full amplitude of 24 ± 2 ppm. We also present new Keck/HIRES radial velocity observations, which we use to measure the orbit and obtain a mass ratio of q = 0.106 ± 0.012. Combining this measurement with the results of a stellar isochrone analysis, we find that the masses of the host star and white dwarf companion are 2.23 ± 0.12 M
⊙ and

, respectively. The effective temperatures of the two components are

K and 15,080 ± 400 K, respectively, and we determine the age of the system to be

Gyr. We use the measured system properties to compute predicted phase-curve amplitudes and find that while the measured Doppler-boosting and mutual illumination components agree well with theory, the ellipsoidal distortion amplitude is significantly underestimated. We detail possible explanations for this discrepancy, including interactions between the dynamical tide of the host star and the tidal bulge and possible nonsynchronous rotation of the host star.
Transfer of Twists from a Mini-filament to Large-scale Loops by Magnetic Reconnection
Authors: Yang Liheng , Yan Xiaoli , Xue Zhike , Li Ting , Wang Jincheng , Li Qiaoling , Cheng Xin
Published: December 2019

With high spatial and temporal resolution, Hα data from the New Vacuum Solar Telescope, X-ray images from the X-ray telescope on board Hinode and simultaneous observations from the Solar Dynamics Observatory, we present multiwavelength observations of the interaction between a mini-filament (MF) and its overlying large-scale active-region loops (ARLs) that occurred in AR 12497 on 2016 February 13. The MF was activated by the convergence and cancellation of the magnetic flux under it. Brightenings first appeared at the junction of the MF and its overlying large-scale ARLs. A blowout jet with some plasma blobs was observed to move along the newly formed large-scale ARLs, and caused the oscillations of these loops. The blowout jet exhibited a counterclockwise rotation due to the untwisting motion of the MF, suggesting that the twist is transferred from the MF to the ARLs. The transferred twist was measured to be about 0.34–0.52 turn. During the interaction progress, a group of hot loops formed in the high-temperature wavelength (94 Å). These hot loops connected the west footpoints of the original ARLs and the east footpoints of the MF. The differential emission measure analysis demonstrated that these hot loops contained a high-temperature component (∼8 MK). Meanwhile the footpoints of the ARLs were finally shifted to the west footpoint of the MF. These observations suggest that magnetic reconnection takes place between the MF and its overlying large-scale ARLs and results in a confined untwisting blowout jet.
The Formation and Evolution of Wide-orbit Stellar Multiples In Magnetized Clouds
Authors: Lee Aaron T. , Offner Stella S. R. , Kratter Kaitlin M. , Smullen Rachel A. , Li Pak Shing
Published: December 2019

Stars rarely form in isolation. Nearly half of the stars in the Milky Way have a companion, and this fraction increases in star-forming regions. However, why some dense cores and filaments form bound pairs while others form single stars remains unclear. We present a set of three-dimensional, gravo-magnetohydrodynamic simulations of turbulent star-forming clouds, aimed at understanding the formation and evolution of multiple-star systems formed through large-scale (≳103 au) turbulent fragmentation. We investigate three global magnetic field strengths, with global mass-to-flux ratios of μ

ϕ
 = 2, 8, and 32. The initial separations of protostars in multiples depend on the global magnetic field strength, with stronger magnetic fields (e.g., μ

ϕ
 = 2) suppressing fragmentation on smaller scales. The overall multiplicity fraction (MF) is between 0.4 and 0.6 for our strong and intermediate magnetic field strengths, which is in agreement with observations. The weak field case has a lower fraction. The MF is relatively constant throughout the simulations, even though stellar densities increase as collapse continues. While the MF rarely exceeds 60% in all three simulations, over 80% of all protostars are part of a binary system at some point. We additionally find that the distribution of binary spin misalignment angles is consistent with a randomized distribution. In all three simulations, several binaries originate with wide separations and dynamically evolve to ≲102 au separations. We show that a simple model of mass accretion and dynamical friction with the gas can explain this orbital evolution.
The Probiotic Bacterium Isolated from Bekasam (Traditional Fermented Food), Lactobacillus Sp. Induces Activation of Gut Mucosal Immune System in Rat
Authors: Husin Syarif , Melizah Ardesy , Alkaff Syifa , Hidayat Rachmat
Published: December 2019

BACKGROUND: Bekasam is one of the traditional foods in South Sumatra, Indonesia, a mixture of fermented fish containing Lactic Acid Bacteria (LAB), Lactobacillus sp. Non-commensal bacteria and probiotics can induce intestinal mucosal immune responses.
AIM: This pilot study aimed to see the efficacy of Lactobacillus sp. to the immune response of the intestinal mucosa by assessing the levels of IgA in the intestinal fluid and markers of T cell populations, such as CD4 and CD8 in the intestinal mucosa.
METHODS: This study was an in vivo experimental study. As many as 30 rats were grouped into 3 treatment groups (doses 107, 108, and 109 CFU/rat/day, for 7 days) and 2 groups of controls (negative control, 10% non-fat milk, and positive control, Lactobacillus casei 108 CFU/rat/day for 7 days). At the end of the treatment, the intestinal mucosa was taken to examine the levels of IgA, CD4 and CD8 using the Enzyme-Linked Immunosorbent Assay (ELISA) method, according to the manuals of each ELISA kit. All displays of research data were presented with means Â± SD. T-test was used to assess the significance of differences.
RESULTS: Secretion of Ig A increased with the addition of Lactobacillus sp. from bekasam. Administration of Lactobacillus sp. yielded no effect on helper T cell level (CD4 markers), as well as on cytotoxic T cell levels (CD8 markers).
CONCLUSION: Lactobacillus sp. probiotic from bekasam improved the intestinal mucosal immune system by increasing the production of Ig A, but exhibited no effect on T lymphocyte cells.
 by increasing the production of Ig A, but exhibited no effect on T lymphocyte cells.
Freshwater diatoms in the Democratic Republic of the Congo: a historical overview of the research and publications
Authors: Cocquyt Christine , Lokele Ndjombo Edit , Tutu Tsamemba Simon , Nshimba Seya wa Malale Hippolyte
Published: December 2019

An overview of the diatom research in the DR Congo is given based on literature data starting in 1938 with the work of Zanon and excluding the East African Lakes as these were already discussed in previous papers. For each literature record the diatom genera mentioned are presented as well as all diatom taxa described from the Congo as new. In total, 106 new taxa were documented, of which Nitzschia with 40 taxa is far the most important genus followed by Navicula s.l. and Pinnularia and with 15 and 13 taxa respectively. Particular attention was paid to the local research of students found in unpublished theses at bachelor, licentiate, master and PhD level. Diatom records in these works are almost all restricted to genus level, although in the last decade an attempt to delimit species can be observed. This accompanies the renewed taxonomic interest in the Congo basin during the last decade. Renewed taxonomic interest can also be seen in the genera: the first period being situated during the lumping period, while more recent works follow the current taxonomic classification, for example Navicula s.l. versus Navicula, Cavinula, Craticula, Diadesmis, Geissleria, Humidophila, Luticola, etc.
Evaluation of a Synthetic Bone Defect Test Model to Aid in the Selection of Materials for Use in Vertebral Body Compression Fracture Repair
Authors: Carroll Michael , Lewis Gladius , Xu J , Moseley Jon , Cole Jantzen , Haggard Warren
Published: December 2019

Abstract

A synthetic test model was developed to assist in screening injectable cements with a focus on mechanical strength for vertebral body compression fracture repair. The two-part defect model consisted of a polyurethane foam cube to simulate trabecular bone and a defect to which various injectable cements could be introduced. In addition, a finite element analysis model was developed and the results were compared to laboratory testing. Agreement was found between the finite element analysis and test results. Once the finite element analysis model was validated with experimental data, an additional finite element analysis was conducted to study various parameters affecting mechanical performance such as simulated bone and cement stiffness. Finite element analysis models were also created using orthotropic bone properties typical of healthy trabecular bone and were compared to various foam stiffnesses. The foam model was a good in vitro representation of actual trabecular bone found in vertebral bodies and is a valid model to evaluate the mechanical strength of injectable cements for percutaneous vertebral body fracture repair.
Use of Cancellous Bone Chips and Demineralized Bone Matrix in the Treatment of Acetabular Osteolysis: Preliminary 2-Year Follow-up
Authors: Etienne Gracia , Ragland Phillip S , Mont Michael A
Published: December 2019

Abstract

Twenty patients (20 hips) who had cementless acetabular revision arthroplasty and were treated with cancellous bone chips mixed with demineralized bone matrix to fill the cavitary defects were studied. At 2-years' follow-up, the grafts were fully incorporated in 18 patients. In addition, the mean Harris Hip Score increased to 89 points from a mean preoperative score of 29 points for the surviving hips. These preliminary findings suggest that the prepackaged demineralized bone matrix and cancellous chips can provide acceptable radiographic and clinical results as an adjunct in the treatment of contained osteolytic acetabular defects.
Functional Outcomes of Bone Graft Substitutes for Benign Bone Tumors
Authors: Gitelis Steven , Virkus Walter , Anderson David , Piasecki Patricia , Yao Ting Kuo
Published: December 2019

Abstract

Benign bone tumors are frequently treated surgically by intralesional excision with grafting. Due to the significant morbidity associated with autogenous graft, there is interest in bone graft substitutes. Ninety-eight consecutive patients with benign bone tumors treated by intralesional excision with bone graft substitutes were retrospectively reviewed. Functional scores using the International Symposium of Limb Salvage (ISOLS) system were obtained at most recent follow-up. The mean functional score was 28.3 out of 30 (94%). Three patients suffered fractures that ultimately healed with management There were no local recurrences. Based on results of this study, bone graft substitutes are a reasonable alternative to autogenous grafting with a successful functional outcome.
Cement Penetration Using a Tibial Punch Cement Pressurizer in Total Knee Arthroplasty
Authors: Diaz-Borjon Efrain , Yamakado Kotaro , Pinilla Roque , Worland Richard L
Published: December 2019

abstract

This study describes a new tibial cement punch pressurizer to enhance cement penetration into the metaphyseal cancellous bone of the tibial plateau. Thirty knees of 15 patients undergoing simultaneous bilateral total knee arthroplasty (TKA) were randomly selected to receive the tibial cement punch pressurizer on one side, with the opposite side serving as control. Using computerized and radiographic evaluation of both knees 2 weeks post-operatively, the punch pressurizer achieved 1.32 times better penetration of the cement. The tibial punch cement pressurizer offers a simple technique to provide reliable cement penetration and tibial component fixation in TKA.
A Survey of Orthopedic Surgeons Regarding DVT Prophylaxis in Foot and Ankle Trauma Surgery
Authors: Wolf Jennifer Moriatis , Digiovanni Christopher W
Published: December 2019

abstract

This study hypothesized that thromboembolism in patients with foot and ankle trauma is higher than currently recognized, and that prophylaxis varies among surgeons. A questionnaire sent to members of two orthopedic specialty societies surveyed the use of thromboembolic prophylaxis over 1 year. Most did not use preoperative prophylaxis. Postoperatively, 44% of surgeons used prophylaxis, most commonly sequential compression devices and low molecular weight heparin. This survey suggests that thromboembolic prophylaxis is used by <50% of surgeons treating foot and ankle trauma. The reported cases of thromboembolism in this study underline the need for a prospective investigation.
Spatial Distribution of Keratan Sulfate in the Rabbit Cornea Following Photorefractive Keratectomy
Authors: Resch Miklós D , Nagy Zoltán Z , Szentmáry Nóra , Máthé Miklós , Kovalszky Ilona , Süveges Ildikó
Published: December 2019

ABSTRACT

PURPOSE: To examine the keratan sulfate content of the stroma and to assess its correlation with the healing process (epithelialization and keratocyte density) after photorefractive keratectomy (PRK).

METHODS: Using an Aesculap M?dit?e MEL 70G.scan excimer laser, -6.0 diopters (6.0-mm diameter, 82 /im photoablation depth), PRK was carried out on the right eye of 32 New Zealand pigmented rabbits. After enucleation (at days 1, 4, 7, 14, and 28 and months 2, 3, and 7; sub-groups of 4 animals), fluorescent immunohistochemistry was performed on sections from the central cornea using monoclonal mouse anti-keratan-sulfate antibody, immunohistochemistry with proliferative cell nuclear antigen antibody, and hematoxylin-eosin histology. The left, untreated eyes served as controls. Cellular morphology and spatial distribution of keratan sulfate were recorded, stromal thickness measured, and keratocyte density calculated.

RESULTS: Keratan sulfate was found on the surface of migrating epithelial cells in the early stage (from days 1 to 7). In the stroma, three phases were noted. Phase 1) Day 1 to 14, intense granular fluorescence appeared in the anterior stroma with hypocellularity. Phase 2) Month 1 to 2, newly synthesized lamellar keratan sulfate restored the repopulating anterior stroma. Endothelial cells became keratan sulfate positive, while in the posterior stroma, lamellar-form keratan sulfate increased from week 1 and peaked at month 1 (100% increase). Phase 3) Month 2 to 7, remodeling and deposition of keratan sulfate was noted, which was produced in phase 2.

CONCLUSIONS: Keratan sulfate was found in the epithelium, stroma, and endothelium. By controlling the interlamellar spacing, keratan sulfate plays a role in postoperative edema, remodeling of the corneal stroma, and simultaneous regulation of inflammation after PRK. [J Refract Surg. 2005;21:485-493.]
Topography-guided Custom Retreatments in 27 Symptomatic Eyes
Authors: Kanellopoulos A John
Published: December 2019

ABSTRACT

PURPOSE: To evaluate the use of topography-guided ablations for refractive irregularities induced by previous surgery.

METHODS: This prospective, non-comparative trial comprised 27 symptomatic eyes with a history of LASIK for myopia that underwent topography-guided treatment with the ALLEGRETTO WAVE system. Pre- and postoperative refraction, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), corneal asphericity (Q value), low contrast sensitivity, and patient's subjective assessment of improvement were measured.

RESULTS: Preoperative data were sphere -0.84±1.37 diopters (D), cylinder -1.55±0.78 D, UCVA 20/49±0.22, BSCVA 20/32±0.15, and Q value 1.46±0.79. Postoperative data at mean 6-month follow-up were: sphere -0.61±0.81 D, cylinder -0.53±0.58 D, UCVA 20/25±0.21 (P<.01), BSCVA 20/21±0.14 (P<.001), and Q value 1.07±0.89. Contrast sensitivity scores improved by 70%. No loss of BSCVA occurred in any patient.

CONCLUSIONS: Topography-guided treatments may be effective in correcting the quality of vision. It should be viewed as a possible two-step procedure due to spherical adjustment that may change refraction unpredictably. [J Refract Surg. 2005;21:S513-S518.]
The Effect of Lubricant Eye Drops on Ocular Wavefront Aberrations
Authors: Airiani Suzanna , Rozell Joshua , Lee Shing M , Braunstein Richard E
Published: December 2019

ABSTRACT

PURPOSE: To study the effect of lubricant eye drop instillation on ocular wavefront aberrations.

METHODS: The wavefront aberrations of the entire optical path of 30 eyes of 15 patients before and following instillation of lubricant eye drops (Bion Tears; Alcon Laboratories Ine, Ft Worth, Tex) were obtained over a 6-mm pupil using a Hartmann-Shack wavefront sensor (WaveScan; VISX Ine, Santa Clara, Calif). Additional computation of root-mean-square (RMS) errors of higher order aberrations from third to sixth order were done using Zernike Tool Software (VISX Ine). Main outcome measures include the mean changes of total higher order aberrations RMS, higher order aberrations, and point spread function (PSF) of the higher order aberrations.

RESULTS: The mean changes of total higher order aberrations following instillation of lubricant eye drops on the right eyes were -0.07 ??? (95% confidence interval [Cl], -0.11 to -0.03) and -0.03 ??? on the left eyes (95% Cl, -0.07 to 0.01). Significant mean changes were noted for coma and trefoil aberrations with a magnitude of -0.08 ??? (95% Cl, -0.12 to -0.03) and -0.09 (95% Cl, -0.13 to -0.05), respectively, as well as a mean change of the PSF of the higher order aberrations (-0.05 diopters, 95% Cl, -0.08 to -0.02) on the right eyes. Although no significant changes in these parameters were demonstrated on the left eyes, a similar trend of changes was observed.

CONCLUSIONS: Ocular wavefront aberrations may change following eye drop instillation as measured objectively by the WaveScan system. This effect should be taken into consideration in the assessment of patients for wavefront-guided laser vision correction procedures. [J Refract Surg. 2005;21:709-715.]
Comparison of Topographic Corneal Irregularity After LASIK and Intrastromal Corneal Ring Segments in the Same Patients
Authors: Naseri Ayman , Forseto Adriana S , Francesconi Claudia M , Hwang David G , Campos Mauro , Nose Walton
Published: December 2019

ABSTRACT

PURPOSE: To retrospectively compare the irregularity of the corneal surfaces of 14 patients after LASIK in 1 eye and placement of intrastromal corneal ring segments (ICRS) in the other eye.

METHODS: In a within-patient comparison, Orbscan corneal topography was used to retrospectively compare the corneal surface irregularity of LASIK-treated and ICRS-treated eyes at an outpatient tertiary-care ophthalmology clinic in Sao Paulo, Brazil. For the anterior corneal surface, irregularity measurements were compared for both the central and peripheral areas of the cornea. The differences between each group were analyzed for statistical significance.

RESULTS: The corneal surfaces of eyes treated with ICRS were found to be more irregular than the corneal surfaces of eyes treated with LASIK, the mean irregularity being 1.91 for LASIK-treated eyes and 3.12 for ICRStreated eyes in the anterior corneal surface and 0.51 for LASIK-treated eyes and 0.87 for ICRS-treated eyes in the posterior corneal surface. A statistically significant difference was noted only in the posterior surfaces.

CONCLUSIONS: When measured with Orbscan topography, ICRS-treated eyes show more corneal surface irregularity than LASIK-treated eyes. The difference in outcome for the two types of treatment may be due to the mechanical effect of the ICRS on the shape of the cornea. [J Refract Surg. 2005;21:722-726.]
Об объясняющей межъязыковые различия и объединяющей разнообразие языков мира универсальной перцептивной модели: детализация
Authors: Попов Сергей
Published: December 2019

Podrobno k univerzalnemu dojemalnemu modelu, ki razlaga medjezikovno razhajanje in enoti raznolikost jezikov svetaČlanek je posvečen razlagi delovanja univerzalnega dojemalnega modela, ki enoti različne jezike in razkriva vzroke za medjezikovno razhajanje. Razlaga sloni na tako imenovanih stopnjah dojemalne sheme, kjer je v obdobju oblikovanja osnovnih jezikovnih struktur najbolj važno povrhnje dojemanje.
Analiza frazeološke variantnosti za slovarski prikaz v eSSKJ-ju in SPP-ju
Authors: Meterc Matej
Published: December 2019

Prispevek predstavlja teoretična in metodološka izhodišča za prikaz frazeoloških in paremioloških variant v Slovarju slovenskega knjižnega jezika (tretja izdaja), ki je na portal Fran dostopen pod imenom eSSKJ, ter v Slovarju pregovorov in sorodnih paremioloških izrazov (SPP), katerega prvi prirastek bo objavljen leta 2020 na istem portalu. Najprej bomo podali razloge za natančno obravnavo variant tako v splošnem kot v specializiranem slovarju. Nato bomo opisali različne metode korpusne analize in vključevanja anketno pridobljenih podatkov vanjo.
Tipologija nestavčnočlenskih nematičnih dopolnil v slovenščini
Authors: Gabrovšek Dejan
Published: December 2019

Prispevek se opira na skoraj stoletje staro tezo Vinogradova in drugih ruskih jezikoslovcev, ki velja za slovanske jezike, namreč da bi bilo bolje kot o dvojici priredje – podredje govoriti o različnih stopnjah odvisnosti med stavki znotraj zložene večstavčne povedi. Tako lahko poleg stavčnočlenskih odvisnikov kot samostojno enoto vpelje (tudi) nematična nestavčnočlenska dopolnila; ta predlagana enota doslej še ni bila deležna podrobnejše sistematične obravnave. Članek poskuša zajeti čim več z vezniki in vezniškimi sredstvi (so)izražanih pomenov.
Harmonic Mitigation Techniques in Smart Distribution Network
Authors: Mebrahtu Fsaha
Published: December 2019

In this chapter various harmonic sources and their effect on the distribution network and its mitigation procedures are discussed. In the distribution network, electrical power is mostly utilized for our daily activity. However, the quality of power in the distribution network is affected by different disturbances. The distribution power quality problems deteriorate the performance of the system. One of the disturbances of the distribution network is harmonic distortion. Disturbances not only produce excessive heat in the devices and appliances used in the daily life of human beings, but also reduce the life of the appliances. Finally, the harmonic distortion mitigation by using active power filter, space vector pulse width modulation, dynamic voltage restorer, voltage phase shift, and fuzzy logic controller is discussed.
Energy Storage System and Its Power Electronic Interface
Authors: Khan Baseem , Degarege Samuel , Mebrahtu Fsaha , Alhelou Hassan
Published: December 2019

This chapter examines the modeling and simulation of energy storage (battery, flywheel, etc.) systems interfaced to the power grid by using power electronic device, like chopper module, Rectifier module, and filter circuits, which are essential to the load balance between supply and demand, and to eliminate harmonics and to ensure efficient, cost effective, and reliable operations. Energy storage system in power grid is the same as memory in computer system. Energy efficiency is a key performance indicator for energy storage system. The energy storage system is the most promising component to enhance the system reliability and flexibility.
Key Processes for the Performance of Work-Integrated Learning in HE
Authors: Nuninger Walter , Châtelet Jean-Marie
Published: December 2019

In a changing business market due to state regulation, funding reductions, and generation evolution, HE providers target a high level of operational learning performance. Work Integrated Learning is a framework that complies with European Standards and Guidelines, leading to increased competences of the citizen all through life and career. But the consistency of the training offer with shareholders' projects is only ensured if a learning organization rigorously monitors the 5-step road map: an improvement cycle that nonetheless allows local adaptation when carrying out the training in the scope of Quality Assurance. Today, more than ever, the issue for excellence (sustainability, efficiency, welfare at work) requires the Pole of Expertise animation, which means training tutors (TIL). The winning-foursome is the new lever for innovation. The tremendous digital integration at all levels of the organization opens new dimensions to executive dashboards to support the change of paradigm between trainees and trainers, then questions training lifetime and leading model for transfer.