bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS KOMPARASI ESTIMASI JUMLAH PENJUALAN PRODUK DENGAN METODE EKSPONENSIAL TUNGGAL PENDEKATAN ADAPTIF DAN METODE EKSPONENSIAL GANDA DUA PARAMETER DARI HOLT
Authors: Aden Aden
Published: September 2019

Persediaan jumlah produk yang akan dijual memerlukan perhitungan yang matang sehingga jumlahnya cukup untuk memenuhi konsumen. Maka dari itu perlu dilakukan prediksi yang tepat guna memenuhi kebutuhan jumlah produk. Tujuan penelitian ini yaitu mengetahui bentuk pola data yang terbentuk dari data hasil penelitian, mengetahui ketepatan penggunaan estimasi Metode Ekponensial Tunggal Pendekatan Adaptif dengan Metode Ekponensial Ganda Dua Parameter dari Holt data jumlah penjulan produk pada Alfamart cabang Kemiri sesuai dengan pola data, analisis Galat U-Thail dan Durbin Waston, dan mengetahui estimasi jumlah produk atau retail ke depan di minimarket Alfamart Cabang Kemiri dengan metode yang lebih tepat antara Metode Eksponensial Tunggal Pendekatan Adaptif dengan Metode Eksponensial Ganda Dua Parameter Dari Holt. Metode penelitian yang digunakan pada penelitian ini yaitu metode penelitian kuantitatif dengan bentuk komparasi antar dua metode perhitungan. Hasil penelitian yang diperoleh yaitu pola data penelitian berbentuk horizontal yang mendekati rata-rata hitung yaitu 360,33, metode yang terbaik yaitu metode pemulusan Tunggal Pendekatan Adaptif dikarenakan data yang diperoleh yaitu data horizontal, nilai U-Thail 0,95, nilai Durbin Waston 1,436, dan estimasi penjualan retail untuk bulan ke depan yaitu sebanyak 340.
PENGARUH KEBIASAAN BELAJAR SISWA DAN KECERDASAN EMOSI SERTA PERHATIAN ORANG TUA TERHADAP PENGUASAAN KONSEP MATEMATIKA
Authors: Sastro Gerry
Published: September 2019

Latar belakang penelitian adalah pendidikan anak bangsa yang cenderung menekankan masalah kecerdasan intelektual tanpa melihat faktor kebiasaan belajar, kecerdasan emosi dan peran orang tua yang sebenarnya penting menunjang keberhasilan siswa dalam meraih prestasi. Tujuan penelitian untuk mengetahui pengaruh kebiasaan belajar dan kecerdasan emosi serta perhatian orang tua secara bersama-sama terhadap penguasaan konsep matematika. Penelitian menggunakan metode survey, teknik pengambilan sampel menggunakan random sampling yang berjumlah 456 siswa dari tiga SMP Swasta di Kecamatan Pamulang Kota Tangerang Selatan. Analisis data menggunakan Regresi Berganda. Hasil penelitian menunjukkan bahwa penguasaan konsep matematika dipengaruhi secara bersama-sama oleh kebiasaan belajar, kecerdasan emosi, dan perhatian orang tua dengan persamaan regresi Ŷ = 49,376 + 0,324 X1 + 0,311 X2 + 0,448 X3. Secara parsial pula penguasaan konsep matematika dipengaruhi oleh kebiasaan belajar. Penguasaan konsep matematika dipengaruhi oleh kecerdasan emosi dan penguasaan konsep matematika dipengaruhi oleh perhatian orang tua. Implikasi dari penelitian adalah perhatian orang tua memberikan kontribusi dominan pada penguasaan konsep matematika dari pada kebiasaan belajar dan kecerdasan emosi. Maka disarankan orang tua untuk memberikan banyak perhatian kepada anaknya untuk meningkatkan hasil belajar matematika.
STUDENT’S SELF-CONCEPT PROFILES IN PROBLEM POSING ACCORDING TO COGNITIVE STYLES: DEVELOPING AN EVIDENCE BASE FOR BEST PRACTICE OF E-LEARNING IN MATHEMATICAL ECONOMICS COURSE AT PAMULANG UNIVERSITY
Authors: Hidayat Angga
Published: September 2019

Penelitian ini merupakan penelitian kualitatif dan bersifat eksploratif yang bertujuan untuk mendeskripsikan konsep diri mahasiswa dalam pengajuan masalah matematika bisnis ditinjau dari perbedaan gaya kognitif, yaitu field dependent dan field independent. Subjek penelitian ini terdiri dari dua mahasiswa , berjenis kelamin perempuan. Penelitian dimulai dengan menentukan subjek penelitian menggunakan instrument GEFT. Perbedaan gaya kognitif, kesamaan jenis kelamin, kemampuan berkomunikasi dan kesediaan mahasiswa juga menjadi pertimbangan peneliti untuk memilih subjek, kemudian dilanjutkan dengan memberikan tugas pemecahan masalah, wawancara dan pengamatan. Pengecekan keabsahan data menggunakan triangulasi waktu. Berdasarkan hasil analisis data, dapat disimpulkan bahwa subjek bergaya kognitif field dependent berusaha dalam memecahkan masalah matematika bisnis walau menghadapi beberapa kesulitan dan merasa tidak yakin dapat memecahkan masalah matematika bisnis dengan benar. Selain itu, subjek bergaya kognitif field dependent merasa gugup, tegang dan khawatir tetapi tidak menunjukan perubahan fisiologis dan menjelaskan secara garis besar tentang pemecahan masalah matematika bisnis. Di sisi lain, subjek bergaya kognitif field independent berusaha terus dalam memecahkan masalah matematika bisnis walau menghadapi kesulitan dan merasa yakin dapat memecahkan masalah matematika bisnis. Subjek bergaya kognitif field independent tidak merasa gugup, tegang dan khawatir tetapi mengeluarkan keringat pada telapak tangan dan menjelaskan secara terperinci tentang pemecahan masalah.
ISOLASI DAN KARAKTERISASI SELULOSA : REVIEW
Authors: Mulyadi Irwan
Published: September 2019

Selulosa, salah satu sumber daya alam terbaharukan yang melimpah di Indonesia. Keberadaan selulosa tidak terlepas dari lignoselulosa. Oleh karena it untuk mendapatkan selulosa harus dilakukan pengisolasian dari lignoselulosa tersebut. Penulisan ini bertujuan untuk mereview tentang isolasi dan karakterisasi selulosa tersebut. Isolasi selulosa dapat dilakukan dengan metode perlakuan hidolisis asam, hidrolisis basa, ledakan uap dan enzimatik. Karakterisasi isolasi dapt menggunakan 4 karakteristik yaitu analisis proxymate terutama kandingan selulosa dan lignin, analisis FTIR, analisis termal, dan analisis morfologi permukaan
PENYELESAIAN MASALAH TRAFFIC ASSIGNMENT DETERMINISTIK DAN APLIKASINYA DALAM PEMODELAN PERPARKIRAN
Authors: Aden Aden
Published: September 2019

Traffic Assignment merupakan suatu permasalahan untuk mencari pola arus pada rute dari verteks satu ke verteks yang lainnya di suatu area perparkiran yang berpatokan terhadap pencarian rute optimum. Deterministik merupakan suatu metode penyelesaian masalah yang berkaitan dengan linier programming,  untuk itu dalam pencarian rute optimum dari verteks satu ke verteks yang lainnya penulis menganalisa dengan metode Algoritma Djikstra secara manual dan metode Algoritma Djikstra dengan menggunakan pemrograman pada program Matlab yang ternyata memperoleh hasil akhir yang sama sebagai implementasi dari Traffic Assignment Deterministik. Dalam pencarian rute optimum pada pemodelan perparkiran bergantung sekali terhadap kapasitas kendaraan perparkiran tersebut dan pelayanan yang meyakinkan. Terlebih dalam traffic Assignment hal kemacetan sangat penting peranannya dalam menentukan rute optimum dan juga model antrian yang dipakai dalam rute tersebut.
ANALISIS JALUR UNTUK PENGARUH ANGKA HARAPAN HIDUP, HARAPAN LAMA SEKOLAH, RATA-RATA LAMA SEKOLAH TERHADAP INDEKS PEMBANGUNAN MANUSIA MELALUI PENGELUARAN RIIL PER KAPITA DI PROVINSI NUSA TENGGARA TIMUR
Authors: Arofah Irvana , Rohimah Siti
Published: September 2019

Indeks Pembangunan Manusia (IPM) merupakan suatu ukuran kondisi sumber daya manusia pada suatu negara. Indeks Pembangunan Manusia mempunyai tiga unsur yaitu kesehatan, pendidikan yang dicapai, dan standar kehidupan atau sering disebut ekonomi. Tujuan penelitian ini untuk mengetahui faktor-faktor Angka Harapan Hidup, Harapan Lama Sekolah,Rata-Rata Lama Sekolah, Terhadap  Indeks Pembangunan Manusia (IPM) Melalui Pengeluaran Riil Per Kapita Di Provinsi Nusa Tenggara Timur. Dalam penelitian ini digunakan analisis jalur dengan menggunakan software SPSS. Analisis jalur mempunyai beberapa tahapan, yaitu Merumuskan hipotesis dan persamaan struktural, Menghitung koefisien jalur secara simultan (keseluruhan) dan secara individual, Menguji kesesuaian antar model analisis jalur, Memaknai dan menyimpulkan. Berdasarkan hasil penelitian menunjukkan bahwa besarnya kontribusi Angka Harapan Hidup  terhadap Indeks Pembangunan Manusia  sebesar 0,095 . Besarnya kontribusi Harapan Lama Sekolah  terhadap Indeks Pembangunan Manusia sebesar 0,187. Besarnya kontribusi Rata-rata Lama Sekolah  Indeks Pembangunan Manusia  sebesar 0,280 . Besarnya kontribusi Pengeluaran Riil PerKapita  terhadap Indeks Pembangunan Manusia  sebesar 0,571.  Besarnya kontribusi secara simultan antara Harapan Hidup , Harapan Lama Sekolah , Rata-rata Lama Sekolah , Pengeluaran Riil PerKapita  terhadap Indeks Pembangunan Manusia  sebesar 0,947
L’accuratezza delle diagnosi infermieristiche: Cross Mapping in un’unità operativa a gestione infermieristica
Authors: Figura Mariachiara , Tibaldi Laura , Chiarini Massimiliano , Giannetta Noemi , Dionisi Sara , Cianciulli Angelo , Pintus Giulia , Pettinelli Debora , Franzoso Valeria , Di Simone Emanuele , Di Muzio Marco
Published: September 2019

Introduction: Nursing profession requires that the specificity of one’s own knowledge to be shared through the use of efficient measurement tools, able to assess, in a particular way, health interventions results. Therefore, it is necessary for the documentation to be produced using a universal and standardised language. The aim of the study is to identify any differences and inconsistencies between the language used in everyday practice and the referred taxonomy indicated by the Company Directives, highlighting the level of accuracy in the formulation of the nursing diagnosis. Materials and Methods: The Cross-mapping of nursing diagnoses formulated in the UOGI of the AOU “Policlinico Umberto I” of Rome, were collected in 2015 through a retrospective cohort study. The sample taken is 99 medical records and 97 nursing diagnoses. Referring to D-Catch, an attempt was made to conduct a grading of the diagnostic terms and to examine the completeness, linguistic appropriateness and accuracy of the diagnoses made, by subjecting the data to descriptive statistical analysis. The standardised language referred to is NANDA-I. Results: “Risk of infection related to possible invasion of microorganism secondary to surgery”, “Risk of falling related to accident history”, “Immobilization syndrome” are the diagnoses that have perfectly responded to a full-match and correspond to 9.4% of the total, while 38.1% was identified with a close match. Discussion: Using resources such as a standardised vocabulary and pre-structured diagnostic concepts can make nursing documentation systematic, less redundant and able to perfectly outline the assistance process. Conducting a study to compare the language adopted with the referred taxonomy allows the identification of existing gaps and the implementation of new practices aimed at improving the outcome, promoting the correct flow of information.
Technological Culture in Professional Development: A Case Study between Brazil and Portugal
Authors: TRACANA Rosa Branca , CAMBRAİA Adão
Published: September 2019

The aim of this work is answering to: what
characteristics of space formation favour and limit Professional Development of
Teacher, in a critical perspective, of Curricular Practice Recreation for
transformation the interactive context? In Computing Course at IPFarroupilha
(Santo Augusto) and in IPG Portugal was created a learning community for
teachers on curricular recreation. We want to analyze the characteristics of
the formative process experienced that provided professional development in the
re-creation of the technological culture in education. It was developed an
analysis of meetings, interviews with Brazilian and Portuguese students and teachers.
For data analysis we use the discursive textual analysis, producing two
interlinked categories: 1) re-creation of the technological culture in
education; 2) professional development in the context under investigation. Each
category was divided into subcategories. The categories allowed to understand
and strengthen the view that the teachers are responsible for the formation of
their peers and clarify characteristics that limit and/or promote the PDT in
the re-creation of the technological culture education. Rebuilding the concept
of technological culture is a movement of professional development required for
the recognition that the school needs to open the doors to this knowledge.
Perfil Nutricional de Pacientes com Câncer de Cavidade Oral em Pré-Tratamento Antineoplásico
Authors: Oliveira Fernanda Pacheco de , Santos Adriana , Viana Mônica Souza , Alves Jocilene Leite , Pinho Nivaldo Barroso de , Reis Patrícia Fonseca dos
Published: September 2019

Introdução: O câncer de cavidade oral pode causar inúmeros sintomas de impacto nutricional, que afetam negativamente a qualidade de vida, aumentando a morbidade e mortalidade. A avaliação nutricional possibilita a detecção e o manejo desses sintomas, devendo ser realizada antes, durante e após o tratamento antineoplásico. Objetivo: Caracterizar o perfil nutricional de pacientes ambulatoriais com câncer de cavidade oral em pré-tratamento antineoplásico, investigar as alterações que comprometem a ingestão alimentar e avaliar o estado nutricional, visando à intervenção o mais precocemente possível, para maior tolerância ao tratamento antineoplásico e prevenção da desnutrição. Método: Estudo transversal com 29 indivíduos de ambos os sexos, entre 30 e 75 anos de idade, portadores de câncer de cavidade oral em pré-tratamento antineoplásico. O perfil nutricional desses pacientes foi analisado de acordo com os sintomas referidos, perda de peso, consistência da dieta, número de refeições diárias, parâmetros bioquímicos, antropométricos e bioimpedância elétrica. Resultados: A maioria dos pacientes se encontrava em estádio clínico IV (65,5%); referiu, no mínimo, dois sintomas de impacto nutricional (85,2%); e apresentou perda de peso grave em seis meses (56,5%). A circunferência muscular do braço e a área muscular do braço foram os parâmetros antropométricos que classificaram o maior percentual de desnutrição. Conclusão: Perda de peso não intencional, dificuldades de deglutição e reduzida ingestão alimentar foram observadas em grande proporção. A prevalência de desnutrição foi elevada e variou conforme o parâmetro utilizado, ressaltando que os parâmetros de avaliação devem ser utilizados complementarmente.
Conhecimento de Universitários da Área da Saúde sobre o Câncer de Cavidade Oral
Authors: Ganzer Carina Balem , Wagner Gabriela , Toriy Ariana Machado , Roussenq Suellen Cristina , Souza Cristiana Pezzi Franco de , Pires Grasiani Breggue , Dias Mirella
Published: September 2019

Introdução: O câncer de cabeça e pescoço engloba um grupo heterogêneo de neoplasias malignas originadas na cavidade oral, faringe, laringe, seios paranasais, cavidade nasal, glândulas salivares e tireoide. Objetivo: Este estudo buscou avaliar o conhecimento dos universitários da área da saúde sobre o câncer de cavidade oral. Método: Estudo do tipo epidemiológico, transversal, descritivo, quali-quantitativo com amostra não probabilística de conveniência. Os universitários receberam, via formulário on-line, um questionário com 24 questões aplicadas que abordavam os fatores de risco, sintomatologia, aspectos clínicos, autoexame, prevenção e tratamento. Resultados: Participaram do estudo 110 universitários da área da saúde (58 = primeiro ano e 52 = último ano), distribuídos nos cursos de fisioterapia, odontologia, psicologia, educação física, enfermagem, medicina e nutrição. Em relação à média de acertos dos questionários, os universitários do primeiro ano obtiveram 77,65% (±21,09) de acertos, e os universitários do último ano, 82,37% (±19,88). As questões que obtiveram menores taxas de acertos foram as relacionadas à incidência do câncer de boca no Brasil; 43 (39%) acertaram e 52 (47,3%) dos universitários desconhecem a idade em que maioria dos casos são diagnosticados. Conclusão: Apesar de o câncer de cavidade oral ser crescente, formas de prevenção e diagnóstico precoce reservam maiores chances de cura. A partir deste estudo, pôde-se concluir que os universitários dos cursos da área da saúde, principalmente do último ano, parecem estar aptos a informar à população a respeito do câncer de cavidade oral.
İmgelerin Gücü, Anlamlandırılması, Olmak/Görünmek Kiplikleri ve Ziya Osman Saba’nın ‘Mesut İnsanlar Fotoğrafhanesi’nde Hüzün
Authors: UÇAN Mehmet Hilmi
Published: September 2019

İnsan düşünür, kendini yönetir, yönlendirir,
eylemde bulunur, vazgeçer, kabul eder, reddeder, mecbur olur, sahip olur,
ister, görünür, inanır, bağlanır, üstlenir, sorumluluk alır. Bu kipliklerin
olumsuz şekilleri de yaşam içinde gözlenebilir. Göstergebilimin kurucu ismi
A.J.Greimas anlatı çözümlemelerini bu kiplikler üzerinden yapar. Bu
kipliklerden /Olmak/ ve /Görünmek/ kiplikleri insanı, insan için dünyanın anlamını
açıklayan iki önemli kipliktir. R.Barthes da birçok eserinde fotoğrafik
göstergelerdeki /Olmak/ ve /Görünmek/ kipliklerinden söz eder. Servet-i Fünun,
Yedi Meşale, İçtihat, Varlık gibi birçok dergide şiirleri yayımlanan Ziya Osman
Saba’nın gözden kaçırılan yanı öykücülüğüdür. Mesut İnsanlar Fotoğrafhanesi,
onun öykülerinin toplandığı kitaptır. Saba’nın Mesut İnsanlar Fotoğrafhanesi
adlı öyküsüne trajik bir anlam kazandıran da ‘poz veren’ anlatıcının ve ‘poz’
alan fotoğrafçının bakış açıları, sergiledikleri /İstemek/, /Olmak/ ve
/Görünmek/ kiplikleridir. Bu yazıda, imgelerin, fotoğrafın
anlamından/anlamlandırılmasından, gücünden söz edilecek ve Mesut İnsanlar
Fotoğrafhanesi adlı öykü /İstemek/, /Olmak/ ve /Görünmek/ kiplikleri
bağlamında okunacaktır.
Bir Cumhuriyet Kadınını Yazılarından Tanımak: İffet Halim Oruz ve Kadın Gazetesi’ndeki Yazıları (1947-1963)
Authors: KARABULUT Sezen
Published: September 2019

Türk
Modernleşme sürecinin başlaması ile birlikte eğitim, kültür ve sosyal alanda
yaşanan değişim ve dönüşümler beraberinde aydın bir sınıfın yetişmesine zemin
hazırlamıştır. Bu aydın zümrenin içerisinde kadınların da yer aldığı
görülmektedir. Dönemin öncüleri, edebi alanda başladıkları çalışmalarını kadın
hareketi alanında da sürdürmüşler ve kadının kamusal alanda aktif olarak yer
almasında önemli adımlar atılmasını sağlamışlardır. Aydın kadınlar denilince
İffet Halim Oruz bu figürler arasında en çok akla gelenlerden biridir. Oruz’un
gerek Türk Kadınlar Birliği’ndeki çalışmaları gerekse de kadın yayınları
konusundaki çalışmaları dikkate değerdir. Tanzimat’la birlikte başlayan kadın
yayıncılığı süreç içerisinde önemli bir gelişme göstermiştir. Ancak kadınlara
yönelik hazırlanan bu yayınların önemli bir kısmı dergi formatında çıkarılmış
ve içerik olarak sınırlı kalmıştır. İffet Halim Oruz başkanlığında 1 Mart
1947’de yayın hayatına başlayan Kadın
Gazetesi ise önemli bir ilki gerçekleştirerek büyük boy, siyasi ve sosyal konulara
öncelikli olarak yer vererek geniş bir içerik ile uzun yıllar yayın hayatına
devam etmiştir. Bu çalışmada Cumhuriyet döneminin aydın Türk kadınlarından biri
olan İffet Halim Oruz’u ve Kadın Gazetesi’ndeki
çalışmalarını tanıtmak amaçlanmıştır. Bunun için İffet Halim Oruz’un 1947-1963
yılları arasında Kadın Gazetesi’nde
yayınlanmış sosyal, siyasi ve eğitim hayatında kadının yeri konularını işleyen
yazıları kategorik olarak incelenmiştir.
Avaliação dos indicadores de sarcopenia e de risco de quedas em idosas
Authors: Da Cruz Amanda Santos , Contenças Thaí­s Santos
Published: September 2019

Objetivo: O objetivo do presente estudo foi avaliar os indicadores de sarcopenia e os fatores de risco de quedas nas idosas hí­gidas acima de 60 anos. Métodos: Estudo transversal, com 30 idosas, no qual foram avaliados os indicadores de sarcopenia, utilizando os seguintes testes: velocidade de marcha, força de preensão manual do braço dominante e não dominante e circunferência da panturrilha. Também utilizamos o questionário SARC-F, para triagem de sarcopenia. Para avaliar os riscos de quedas e preocupação em cair, utilizaram-se as escalas Downton e Falls Efficacy Scale International (FES-I Brasil) respectivamente. As pacientes foram divididas em três grupos: G1 idosas jovens de 60 a 69 anos; G2 idosas de 70 a 79 anos; G3 muito idosas com idade igual ou superior a 80 anos. Resultados: Houve uma pequena diminuição da velocidade de marcha apenas no G3, todos os grupos apresentaram diminuição na força de preensão manual do braço dominante e não dominante. Quanto às escalas aplicadas, os grupos G2 e G3 apresentaram históricos de quedas esporádicas e todos os grupos apresentaram alto risco de quedas. Conclusão: Conclui-se com o presente estudo que todos os grupos avaliados apresentaram uma diminuição da força muscular e também um alto risco de quedas, entretanto nenhum dos grupos apresentou sarcopenia.
SETDB1 mediated histone H3 lysine 9 methylation suppresses MLL-fusion target expression and leukemic transformation
Authors: James Ropa  , Nirmalya Saha  , Hsiangyu Hu  , Luke F. Peterson  , Moshe Talpaz  , Andrew G. Muntean
Published: September 2019

Epigenetic regulators play a critical role in normal and malignant hematopoiesis. Deregulation, including epigenetic deregulation, of the HOXA gene cluster drives transformation of about 50% of acute myeloid leukemia. We recently showed that the Histone 3 Lysine 9 methyltransferase SETDB1 negatively regulates the expression of the pro-leukemic genes Hoxa9 and its cofactor Meis1 through deposition of promoter H3K9 trimethylation in MLL-AF9 leukemia cells. Here, we investigated the biological impact of altered SETDB1 expression and changes in H3K9 methylation on acute myeloid leukemia. We demonstrate that SETDB1 expression is correlated to disease status and overall survival in acute myeloid leukemia patients. We recapitulated these findings in mice, where high expression of SETDB1 delayed MLL-AF9 mediated disease progression by promoting differentiation of leukemia cells. We also explored the biological impact of treating normal and malignant hematopoietic cells with an H3K9 methyltransferase inhibitor, UNC0638. While myeloid leukemia cells demonstrate cytotoxicity to UNC0638 treatment, normal bone marrow cells exhibit an expansion of cKit+ hematopoietic stem and progenitor cells. Consistent with these data, we show that bone marrow treated with UNC0638 is more amenable to transformation by MLL-AF9. Next generation sequencing of leukemia cells shows that high expression of SETDB1 induces repressive changes to the promoter epigenome and downregulation of genes linked with acute myeloid leukemia, including Dock1 and the MLL-AF9 target genes Hoxa9, Six1, and others. These data reveal novel targets of SETDB1 in leukemia that point to a role for SETDB1 in negatively regulating pro-leukemic target genes and suppressing acute myeloid leukemia.
Firm Performance: An Empirical Study of Vietnam’s Information Technology Companies
Authors: Pham Thi Bich Ngoc
Published: September 2019

The purpose of this paper is to contribute to the limited previous research on intra-organizational knowledge transfer, by examining the impact of particular organizational factors (IT systems, organizational culture, organizational structure and incentive systems) on the process of knowledge transfer within IT companies in Vietnam and the relationship between the knowledge transfer process and its organizational performance. A survey of 36 companies out of 200 software companies in Hanoi and Ho Chi Minh city, targeted at 900 technical staff, middle managers and top managers, was conducted. The study findings, based on a sample response rate of 24 per cent, indicated that a culture of high solidarity, adaptability and collaboration was proved to have the strongest impact on the process of knowledge transfer and company performance. It was also found that a transparent and flexible incentive system motivated individuals to exchange and utilize knowledge in their daily work, that a high level of centralization and formalization hindered the flow of knowledge, and the effect of IT tools on the knowledge transfer process remained weak. Overall, the findings of the study indicated that organizational factors and intra-organizational knowledge transfer processes have positive correlations with organizational performance.
REVITALISASI DESAIN ILUMINASI PADA NASKAH JAWA KUNO DI MUSEUM RADYA PUSTAKA SURAKARTA
Authors: Sulaiman Annas Marzuki , Bastian Henry
Published: September 2019

AbstrakSalah satu bentuk seni yang paling menarik dari budaya visual klasik nusantara adalah seni dekorasi dalam bentuk desain iluminasi yang dapat ditemukan dalam naskah kuno yang tersebar di nusantara. Di Jawa Tengah, desain iluminasi dapat ditemui dalam koleksi naskah kuno Jawa yang disimpan di perpustakaan istana Mangkunegaran dan perpustakaan museum Radya Pustaka Surakarta. Namun keindahan dan keunikan desain iluminasi yang ada dalam naskah Jawa kuno tersebut hanya tersimpan di perpustakaan dan museum, sehingga belum bisa digunakan selain sebagai obyek penelitian dan kepentingan pendidikan. Penelitian ini bertujuan untuk: 1) Menginventarisir dan mengidentifikasi desain iluminasi naskah Jawa kuno sebagai bentuk visual. 2) Merevitalisasi desain iluminasi yang berada dalam naskah kuno Jawa ke dalam bentuk vektor digital sehingga dapat digunakan lebih mudah dan lebih luas. Penelitian ini menggunakan metode kualitatif untuk menjelaskan masalah melalui pengumpulan data dari berbagai sumber yang telah ditentukan. Kata kunci: Iluminasi, Naskah Jawa Kuno, Ornamen, Revitalisasi AbstractOne form of art that most interesting from the classic visual culture of the archipelago is the art of decorating in the form of illumination design that can be found in ancient manuscripts spread throughout the archipelago. In Central Java, the illumination design can be found in the collection of ancient Javanese manuscripts that are stored in the library of Mangkunegaran palace and the library of the Radya Pustaka Surakarta museum. However the beauty and uniqueness of the illumination designs that exist on the ancient Javanese manuscripts are only stored in the library and museum, so it can not be used In addition to providing a research object and educational purpose. These study aims are 1) To Inventory and identify the design illumination of the ancient Javanese manuscript as a visual form. 2) Revitalize the illumination designs that are stored in the ancient Javanese manuscript into a digital vector form so that it can be used easier and broader. This study used qualitative methods that explain the problem through the collection of data from various sources appointed. Keywords: Illumination, Javanese Old Manuscript, Ornament, Revitalization
РІЗНІ ПІДХОДИ ДО РОЗРАХУНКУ КОНСТРУКЦІЙ НА ДИНАМІЧНІ ВПЛИВИ
Authors: ГОРОДЕЦЬКИЙ О.С. , ГЕНЗЕРСЬКИЙ Ю.В.
Published: September 2019

Метою роботи є порівняння різних підходів до розрахунку наслідків сейсмічного впливу на будівлі і споруди. Розглядаються три основні групи: методи, засновані на спектральному аналізі, наближені методи обліку фізичної нелінійності, «Pushover Analysis», методи прямого інтегрування рівнянь руху. Описано основні принципи реалізації «Pushover Analysis» в програмному комплексі «ЛІРА САПР». За всіма реалізованими методами були проведені порівняльні розрахунки для тестової моделі. Це рамно-в’язевий каркас з фундаментною плитою на пружній основі; кількість вузлів - 13 613; кількість елементів – 18 316; кількість рівнянь в матриці жорсткості – 71 575; час розрахунку – 0,78 хв. Проаналізовано результати, отримані за дев'ятьма різними методами обчислення сейсмічних навантажень. Для повного та достовірного опису напружено-деформованого стану будь-якої будівлі необхідно не тільки врахувати абсолютно всі фактори, що описують реальний об'єкт, такі, як його геометричні параметри, фізико-механічні властивості матеріалу, формування початкових напружень і деформацій при зведенні будівлі, але і з високим ступенем точності визначити зовнішні впливи та їх характер. Система «Динаміка плюс», що реалізована в ПК «ЛІРА САПР», дозволяє моделювати поведінку конструкції при динамічних впливах в часі. Проаналізовано результати, отримані за дев'ятьма різними методиками розрахунку сейсмічних навантажень. Перевірено збіг та відмінності методів, основаних на різних передумовах. Показано, що за ДБН В.1.1-12:2014 «Будівництво в сейсмічних районах України» отримано меньші значення зусиль і переміщень, тобто можемо спостерігати деяке «пом'якшення» нормативів, що давно очікують проектувальники.
Robert Southey and his Age: Ageing, Old Age and the Days of Old
Authors: Pratt Lynda
Published: September 2019

Throughout a four-decade career, the controversial poet, historian, biographer and essayist Robert Southey explored the trajectories both of his own individual life and of the time and the society in which he lived. Using a range of published and unpublished sources, including Southey's vast correspondence, this essay will track this preoccupation for the first time and consider its implications for understanding both of Southey and of Romanticism.
Individualización y riesgo de desempleo en los periódicos del norte de México
Authors: Reyna García Víctor Hugo
Published: September 2019

Abstract: The present article analyzes the relationship between the individualization of labor relations and the actualization or staging of unemployment risk in different newspapers in northern Mexico. Once defined as pioneers in the modernization of Mexican journalism, newspapers in the region have also distinguished themselves by their use of direct contracting schemes with their employees. Based on Beck’s theory of labor and fieldwork conducted in Baja California, Nuevo León, and Sonora, this study describes the experiences and perceptions of journalists who work in these organizations concerning their labor relations and employment continuity. Our results revealed the unintended consequences of the modernizing project.
Структура та характер приміщення № 21 городища Дикий Сад
Authors: Horbenko Kyrylo , Smyrnov Oleksandr
Published: September 2019

У статті розкрито особливості приміщення № 21, що розташовувалося на території «ближнього передмістя» городища доби фінального бронзового віку Дикий Сад у місті Миколаїв. Охарактеризовані архітектурна структура та принципи будови, а також особливості внутрішнього заповнення ям. Проаналізовано матеріальні предмети (керамічний посуд, вироби з кістки, рогу, глини, каменю, бронзи), що зафіксовано у культурному шарі. Встановлено, що приміщення № 21 було господарсько-виробничою майстернею зі складною системою багатофункціональних ям (стовпові, господарські, виробничі, ритуальні).
Два кістяні гральні набори з Ольвії
Authors: Vitryk Iryna , Kuzmishchev Oleksandr
Published: September 2019

Світ дитинства у давньогрецьких колоніях Північного Причорномор’я залишається ще недостатньо вивченим. Важливою складовою повсякдення кожної дитини є різноманітні ігри, які допомагають адаптуватися до дорослого життя. Публікація вводить до наукового обігу знахідку низки предметів грального призначення. У роботі зроблена спроба реконструкції однієї з дитячих ігор з використанням фалангових і таранних (астрагалів) кісток домашніх тварин, яка побутувала у кінці V – на початку IV ст. до н.е. у давньогрецькій колонії Ольвія.
Керамічні ливарні форми для виготовлення античних світильників
Authors: Sheiko Iryna
Published: September 2019

Розглядаються глиняні ливарні форми античних світильників і матриця для їх виготовлення, що були знайдені в Ольвії під час розкопок попередніх років. Знахідки складають рідкісний тип виробів як для Північно-Причорноморського регіону. Автором здійснено пошук близьких аналогій та уточнено датування згаданих форм. Крім того, актуалізовано питання технології виробництва античних глиняних світильників за допомогою таких форм.
Причини конфліктів між парафіяльними ієреями Пирятинської протопопії другої половини XVIII століття
Authors: Dmytrenko Vitalii
Published: September 2019

У статті проаналізовані конфлікти між парафіяльними священиками Пирятинської протопопії другої половини XVIII ст. З’ясовано статистику конфліктів і кількість ієреїв втягнутих у них. Проаналізовано суть конфліктів. Встановлені головні причини протистоянь. Розглянуто зміст основних конфліктних ситуацій.
Stability of Biological Activity of Frozen β-lactams over Time as Assessed by Time-Lapsed Broth Microdilutions
Authors: Leite Gleice , Lawandi Alexander , Cheng Matthew P. , Lee Todd
Published: September 2019

To evaluate the antimicrobial agent’s stability stored at −80 °C, six β-lactams (meropenem, ertapenem, imipenem, ceftriaxone, ceftazidime, and piperacillin-tazobactam) were studied using the broth microdilution (BMD). The minimum inhibitory concentration (MIC) remained accurate with the same amount of frozen drug for at least six months. Thereafter, there was a diminishing drug concentration due to instability. At this temperature, most β-lactams can be frozen as a stock concentration for up to six months without a significant loss in antibiotic activity.
The Targeting of RNA Polymerase I Transcription Using CX-5461 in Combination with Radiation Enhances Tumour Cell Killing Effects in Human Solid Cancers
Authors: Ismael Mohammed , Webb Roger , Ajaz Mazhar , Kirkby Karen J. , Coley Helen M.
Published: September 2019

An increased rate of cellular proliferation is a hallmark of cancer and may be accompanied by an increase in ribosome biogenesis and dysregulation in rRNA synthesis. In this regard, CX-5461 has been developed as a novel RNA polymerase I inhibitor and is currently in Phase I/II clinical trials for solid and hematological malignancies. In the present study, interactions between CX-5461 and single-dose X-ray exposure were assessed using isobologram analysis using MTS assay and drug-induced cell death was assessed using flow cytometric, confocal microscopy and Western blot analysis. Combination treatments involving CX-5461 and single-dose X-ray exposure highlighted increased effectiveness compared to individual treatment alone in the CaSki cervical cancer line, with marked synergistic interaction occurring within the low-drug (50 nM) and low-dose radiation range (2–6 Gy). Cell lines challenged with CX-5461 demonstrated the presence of DNA damage, induction of apoptosis, autophagy and senescence alongside high percentages of G2/M cell cycle arrest. In addition, we report preferential sensitivity of ovarian cancer cells with BRCA2 mutation to this novel agent. Taken together, CX-5461 displayed a broad spectrum of activity in a panel of solid cancer cell lines with IC50 values ranging from 35 nM to >1 µM. The work described herein identifies the synergistic effects of CX-5461 in combination with X-rays in solid cancers and may also aid in the design of clinical trials involving this novel agent.
Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors
Authors: Wu Xinhui , van Dijk Eline M. , Ng-Blichfeldt John-Poul , Bos I. Sophie T. , Ciminieri Chiara , Königshoff Melanie , Kistemaker Loes E.M. , Gosens Reinoud
Published: September 2019

Chronic obstructive pulmonary disease (COPD) represents a worldwide concern with high morbidity and mortality, and is believed to be associated with accelerated ageing of the lung. Alveolar abnormalities leading to emphysema are a key characteristic of COPD. Pulmonary alveolar epithelial type 2 cells (AT2) produce surfactant and function as progenitors for type 1 cells. Increasing evidence shows elevated WNT-5A/B expression in ageing and in COPD that may contribute to the disease process. However, supportive roles for WNT-5A/B in lung regeneration were also reported in different studies. Thus, we explored the role of WNT-5A/B on alveolar epithelial progenitors (AEPs) in more detail. We established a Precision-Cut-Lung Slices (PCLS) model and a lung organoid model by co-culturing epithelial cells (EpCAM+/CD45-/CD31-) with fibroblasts in matrigel in vitro to study the impact of WNT-5A and WNT-5B. Our results show that WNT-5A and WNT-5B repress the growth of epithelial progenitors with WNT-5B preferentially restraining the growth and differentiation of alveolar epithelial progenitors. We provide evidence that both WNT-5A and WNT-5B negatively regulate the canonical WNT signaling pathway in alveolar epithelium. Taken together, these findings reveal the functional impact of WNT-5A/5B signaling on alveolar epithelial progenitors in the lung, which may contribute to defective alveolar repair in COPD.
Intracellular Signals Activated by Canonical Wnt Ligands Independent of GSK3 Inhibition and β-Catenin Stabilization
Authors: García de Herreros Antonio , Duñach Mireia
Published: September 2019

In contrast to non-canonical ligands, canonical Wnts promote the stabilization of β-catenin, which is a prerequisite for formation of the TCF4/β-catenin transcriptional complex and activation of its target genes. This pathway is initiated by binding of Wnt ligands to the Frizzled/LRP5/6 receptor complex, and it increases the half-life of β-catenin by precluding the phosphorylation of β-catenin by GSK3 and its binding to the βTrCP1 ubiquitin ligase. Other intercellular signals are also activated by Wnt ligands that do not inhibit GSK3 and increase β-catenin protein but that either facilitate β-catenin transcriptional activity or stimulate other transcriptional factors that cooperate with it. In this review, we describe the layers of complexity of these signals and discuss their crosstalk with β-catenin in activation of transcriptional targets.
Special Issue: “Thin Films for Energy Harvesting, Conversion, and Storage”
Authors: Chen Zhong , Zhao Xin , Tang Yuxin
Published: September 2019

Efficient clean energy harvesting, conversion, and storage technologies are of immense importance for the sustainable development of human society. To this end, scientists have made significant advances in recent years regarding new materials and devices for improving the energy conversion efficiency for photovoltaics, thermoelectric generation, photoelectrochemical/electrolytic hydrogen generation, and rechargeable metal ion batteries. The aim of this Special Issue is to provide a platform for research scientists and engineers in these areas to demonstrate and exchange their latest research findings. This thematic topic undoubtedly represents an extremely important technological direction, covering materials processing, characterization, simulation, and performance evaluation of thin films used in energy harvesting, conversion, and storage.
Influence of Sputtering Power of ZrB2 Target on Structure and Properties of Nanocomposite Zr-B-O Films
Authors: Xu Yang , Mao Dong , Dong Lei , Zhao Mengli , Wu Jie , Li Dejun
Published: September 2019

The nanocomposite Zr-B-O films based on ZrB2 and ZrO2 are successfully deposited on Si (100) and stainless-steel substrates via a multi-target magnetron co-sputtering system. The influence of the sputtering power of ZrB2 target on sample structure and performance was analyzed by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectrometer (XPS). Nano scratch tests were conducted to measure the films’ mechanical properties. Their oxidation resistance in an aerobic environment was tested by high-temperature oxidation in a muffle furnace. Corrosion behaviors of the Zr-B-O films were evaluated by potentiodynamic polarization and electrochemical impedance spectroscopy. It shows that the interior of the composite films has a high degree of non-crystallization. The maximum hardness (26.76 GPa) and corresponding elastic modulus (268.05 Gpa) of the film were obtained at the sputtering power of 120 W. The hardest film also shows the better oxidation resistance with a mass change of around 0.1% before and after oxidation under 1000 °C for 1 h. However, the corrosion resistance of Zr-B-O nanocomposite films is negatively correlated with the power of ZrB2, which is related to the microstructure of the composite film.
Bioactive Coating on Titanium Dental Implants for Improved Anticorrosion Protection: A Combined Experimental and Theoretical Study
Authors: Katić Jozefina , Šarić Ankica , Despotović Ines , Matijaković Nives , Petković Marin , Petrović Željka
Published: September 2019

In recent years, extensive studies have been continuously undertaken on the design of bioactive and biomimetic dental implant surfaces due to the need for improvement of the implant–bone interface properties. In this paper, the titanium dental implant surface was modified by bioactive vitamin D3 molecules by a self-assembly process in order to form an improved anticorrosion coating. Surface characterization of the modified implant was performed by field emission scanning electron microscopy (FE-SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), and contact angle measurements (CA). The implant’s electrochemical stability during exposure to an artificial saliva solution was monitored in situ by electrochemical impedance spectroscopy (EIS). The experimental results obtained were corroborated by means of quantum chemical calculations at the density functional theory level (DFT). The formation mechanism of the coating onto the titanium implant surface was proposed. During a prolonged immersion period, the bioactive coating effectively prevented a corrosive attack on the underlying titanium (polarization resistance in order of 107 Ω cm2) with ~95% protection effectiveness.
Contact Angle Profiles for Droplets on Omniphilic Surfaces in the Presence of Tangential Forces
Authors: Kostoglou Margaritis , Karapantsios Thodoris
Published: September 2019

In real life, sessile droplets usually have a three-dimensional shape, making it difficult to understand their forced wetting behavior, both from an experimental and a theoretical perspective. Even in the case of spreading under quasi-static conditions, where the droplet shape is described by the Young–Laplace equation, there is no fundamental approach to describe the contact line evolution. In the present work, a few existing approaches on this issue are analyzed and assessed. It is shown that an experimentally inspired fixed shape for the contact line of droplets that are spreading under the action of tangential forces can be considered equivalent to a theory for contact line motion. There is a lack of experimental data for contact line evolution under arbitrary scenarios of forces. Such data will be very helpful for the further development of the suggested approach to contact line motion. Of particular interest is the case of small contact angle droplets, for which a top view can clearly indicate the contact line location. On the contrary, in such droplets, the direct experimental measurement of contact angle profile is very difficult. This must be estimated theoretically; thus, a special approach has been developed here for this purpose.
Entropy Measures for Data Analysis: Theory, Algorithms and Applications
Authors: Keller Karsten
Published: September 2019

Entropies and entropy-like quantities are playing an increasing role in modern non-linear data analysis and beyond [...]
Estimating Flight Characteristics of Anomalous Unidentified Aerial Vehicles
Authors: Knuth Kevin H. , Powell Robert M. , Reali Peter A.
Published: September 2019

Several Unidentified Aerial Phenomena (UAP) encountered by military, commercial, and civilian aircraft have been reported to be structured craft that exhibit ‘impossible’ flight characteristics. We consider a handful of well-documented encounters, including the 2004 encounters with the Nimitz Carrier Group off the coast of California, and estimate lower bounds on the accelerations exhibited by the craft during the observed maneuvers. Estimated accelerations range from almost 100 g to 1000s of gs with no observed air disturbance, no sonic booms, and no evidence of excessive heat commensurate with even the minimal estimated energies. In accordance with observations, the estimated parameters describing the behavior of these craft are both anomalous and surprising. The extreme estimated flight characteristics reveal that these observations are either fabricated or seriously in error, or that these craft exhibit technology far more advanced than any known craft on Earth. In many cases, the number and quality of witnesses, the variety of roles they played in the encounters, and the equipment used to track and record the craft favor the latter hypothesis that these are indeed technologically advanced craft. The observed flight characteristics of these craft are consistent with the flight characteristics required for interstellar travel, i.e., if these observed accelerations were sustainable in space, then these craft could easily reach relativistic speeds within a matter of minutes to hours and cover interstellar distances in a matter of days to weeks, proper time.
An Embedded Platform for Testbed Implementation of Multi-Agent System in Building Energy Management System
Authors: Soetedjo Aryuanto , Nakhoda Yusuf Ismail , Saleh Choirul
Published: September 2019

This paper presents a hardware testbed for testing the building energy management system (BEMS) based-on the multi agent system (MAS). The objective of BEMS is to maximize user comfort while minimizing the energy extracted from the grid. The proposed system implements a multi-objective optimization technique using a genetic algorithm (GA) and the fuzzy logic controller (FLC) to control the room temperature and illumination setpoints. The agents are implemented on the low cost embedded systems equipped with the WiFi communication for communicating between the agents. The photovoltaic (PV)-battery system, the air conditioning system, the lighting system, and the electrical loads are modeled and simulated on the embedded hardware. The popular communication protocols such as Message Queuing Telemetry Transport (MQTT) and Modbus TCP/IP are adopted for integrating the proposed MAS with the existing infrastructures and devices. The experimental results show that the sampling time of the proposed system is 16.50 s. Therefore it is suitable for implementing the BEMS in a real-time where the data are updated in an hourly or minutely basis. Further, the proposed optimization technique shows better results in optimizing the comfort index and the energy extracted from the grid compared to the existing methods.