bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis, Optimization and Molecular Characterization of PHB Positive Bacteria Isolated from Agricultural Soil Sample
Authors: W.G Jeevitha , Premila J.M Sasi , S. Mahitha , M. Mahalakshmi
Published: November 2023

Polyhydroxybutyrates are the widely studied biopolymer because of its biodegradability and non-toxic effect in the environment. This work focused on the isolation, screening, characterization and optimization of the PHB producing bacteria from agricultural soil. About eighty percentage of the isolated bacteria were identified as PHB producing bacteria after Sudan Black Blue staining. Among them three colonies were randomly selected and their morphologically and biochemically characterized. The biopolymer was extracted using sodium hypochlorite method. Potent PHB producer (WJSP1) (13.5µg/ml) was identified by crotonic acid assay. The functional groups of the produced PHB were identified by Fourier Transform Infra-Red spectroscopy (FTIR). The presence of functional groups like carbon group, C=O ester group, CH group, carbonyl group, carboxyl group which was corelated with the peak values1454.33cm-1, 1724.36 cm-1, 1274.95 cm-1, 1049.28 cm-1, 1280-1053 cm-1 indicates the presence of PHB. The potent producer (WJSP1) was optimized under different conditions to achieve the best condition for the production of PHB. The maximum production was obtained at the temperature - 37˚C, the carbon source - glucose, pH - 7 and at a time period of 72 hours. 16SrRNA sequencing was performed and the organism was identified as Bacillus cereus from the BLST (Basic Local Alignment Search Tool). A phylogenetic tree was constructed and the sequence was submitted in GENBANK (Accession No: OR192860). The isolated bacteria Bacillus cereus is an efficient producer of PHB under laboratory condition in presence of glucose as a chief carbon source. Large scale production of PHB can be done in large scale fermenters in industries. Large scale production of PHB will help the environment to get rid of the petroleum-based bioplastics.
Treating Periprosthetic Joint Infection With Silver-Impregnated Carbon-Coated Spacers: Mid-Term Outcomes
Authors: Malyuchenko Leonid I. , Nikolaev Nikolay S. , Yakovlev Vadim V. , Preobrazhenskaya Elena V.
Published: November 2023

Background. Periprosthetic joint infection (PJI) is a severe complication of arthroplasty. The widely accepted treatment standard for PJI is a two-stage revision arthroplasty involving the articulating spacers. The implant surface provides an ideal environment for bacterial adhesion, facilitating mature biofilm formation. To prevent bacterial adhesion effectively, the surface of the implanted device must be modified with an efficient coating. The ability of a modified coating based on two-dimensional linear carbon chains (2D LCC) with silver (Ag) impregnation to inhibit biofilm formation and provide efficient bacterial eradication has been investigated in several experimental studies. However, there is a lack of publications on clinical studies evaluating the effectiveness of such coatings.
The aim of the study — to assess mid-term outcomes of knee and hip PJI treatment using spacers coated with two-dimensional linear carbon chains impregnated with silver.
Methods. This study is based on the results of the examination and two-stage revision arthroplasty of 144 patients with newly diagnosed knee and hip PJI. Patients were divided into two groups: the first (main) group received articulating spacers coated with 2D LCC+Ag, while the second (control) group received articulating spacers with antibiotics. Anamnestic, clinical, laboratory, microbiological, and statistical methods were used in this study. The evaluation of short-term results was performed using the KSS, Harris, VAS, and EQ-5D-5L scales at 3 months after surgery, and mid-term results were assessed at 2 years.
Results. The study confirmed the high antibiofilm activity and safety of spacers coated with 2D LCC+Ag. Both groups showed a reduction in inflammation markers during treatment. Before the second stage of treatment, both groups experienced a statistically significant decrease in CRP, procalcitonin, and presepsin levels, as well as synovial cytosis and neutrophil content. The frequency of recurrences after two-stage treatment was significantly lower in the first group compared to the second group. In the mid-term period, the first group had higher scores on the KSS and Harris scales by 20.5 and 7.0 points, respectively. Results on the EQ-5D-5L were 10/0.08 points higher, and the intensity of pain according to VAS was three times lower in the first group.
Conclusion. The use of spacers coated with 2D LCC+Ag allows for a faster resolution of the inflammatory process, reduces the incidence of PJI recurrences, and predicts active protection of the implant surface from microbial colonization and biofilm formation. This, combined with antibiotic prophylaxis, provides a favorable therapeutic and preventive effect against PJI recurrence.
Galectin-3 as a modulator of cytokine-mediated lymphocyte cooperation in vitro
Authors: Vasil’eva Olga A. , Prokhorenko T. S. , Kolobovnikova Y. V. , Poletika V. S. , Urazova O. I. , Kononova T. E. , Churina E. G. , Reynhardt G. V. , Kurnosenko A. V.
Published: November 2023

Aim of the study. To investigate the effect of recombinant galectin-3 on the cytokines secretion of various subpopulations of helper-lymphocytes (Th1, Th2, Th17, Treg) in culture in vitro. Material and methods. The material for the study was peripheral blood from healthy people (n=17), from which lymphocytes were isolated by gradient centrifugation. Lymphocytes were cultured for 72 hours in a CO2-incubator with recombinant galectin-3 and activating antibodies (antiCD3/antiCD28). The concentration of cytokines (IL-10, IL-13, IL-17A, IL-22, IFN, TNF, TGF1) in the supernatants of lymphocyte cultures was determined by enzyme immunoassay. Results. Recombinant galectin-3 in vitro enhanced the secretion of IL-17A, IL-22 by lymphocytes, acting at a dose of 0.5 g/ml; IL-13, TNF and IFN at doses of 0.5 g/ml and 1 /ml (more pronounced when acting at a dose of 0.5 g/ml) and inhibited the production of IL-17, IL-22 at a dose of 1 g/ml and IL-10, TGF1 when testing both concentrations. Conclusion: Galectin-3 has a dose-dependent modulating effect on the cytokine-producing function of healthy donors lymphocytes in vitro. Functional imbalance in blood lymphocytes under the action of recombinant galectin-3 is manifested by induction of pro-inflammatory (IFN, IL-17, IL-22, TNF) and anti-inflammatory (interleukin-13) cytokines secretion, against the background of oppression of the suppressor cytokines (IL-10 and TGF1) production. A detailed study of the immunotropic effects of galectin-3 in relation to individual lymphocytes subpopulations is relevant from the view point of development new approaches to the treatment of tumor and autoimmune diseases accompanied by excessive production of this lectin.
Influence of metabolic acidosis on erythrocyte addrenoreactivity in newborn
Authors: Denisenko O. D. , Perepelitsa S. A. , Litvinova Larisa S.
Published: November 2023

The aim of this work was to study the indicators of adrenoreactivity in the residual cord blood of full-term newborns, depending on the degree of acidosis. The study of the acid-base state and gases of the residual umbilical cord blood of newborns made it possible to evaluate the indicators of the diagnostic criteria for acidosis and highlight the degree of its severity in children at birth. Adrenoreactive properties of erythrocytes were assessed by the method of quantitative assessment of the degree of inhibition of hypoosmotic hemolysis of erythrocytes in the presence of beta-blockers and adrenoreactivity of the body was determined in 58 newborns. It was established that the violation of metabolic processes in the body of newborns was accompanied by activation of the sympathoadrenal system to varying degrees. The increase in metabolic acidosis in children is associated with a decrease in the body’s adrenoreactivity. The level of indicators of β-ARM of erythrocytes depends on the severity and duration of hypoxia.
A Study on Improvement the Efficiency Measurement of Traditional Market by DEA
Authors:   The Korean Logistics Research Association, Li Ze-Lin , Yoo Byong-Kook
Published: November 2023

In order to increase the effectiveness of traditional market policies, in which enormous funds are invested, it can be said that objective and transparent performance evaluation of traditional markets takes precedence. This study proposed two improvements to the existing DEA method in order to improve efficiency studies on traditional markets. In other words, by using a two-step approach using bootstrap, we first calculated the bias-corrected efficiency and examined how external environmental factors affect the efficiency of the traditional market. First, in order to improve the current DEA efficiency index, which is overestimated based on a finite number of samples, we tried to obtain a bias-corrected efficiency index through bootstrapping. This improvement has caused significant changes in the efficiency rankings among existing traditional markets. Second, truncated regression analysis was conducted by bootstrapping to explain the differences in efficiency between traditional markets that inevitably occur depending on the external environment such as location of traditional markets. As a result, it was found that the existence of large retail stores had a negative effect on the efficiency of traditional markets, while the existence of public facilities and transportation facilities had a positive effect on efficiency. If such an external environment becomes an important cause for the difference in efficiency between traditional markets, regardless of internal management efforts in traditional markets, it can be said that appropriate adjustments and modifications are required in performance evaluation.
Continuous Intention to Use of Chinese Mobile Dimple Payment Service
Authors:   The Korean Logistics Research Association, Li Jian-Hui , Kim Moon-Hong
Published: November 2023

The main purpose of this study aims to present implications for the supervision and management of mobile simple payment services by identifying the impact of system benefits and disadvantages on perceived value, and to present implications for the security and development direction of mobile simple payment services by verifying the moderating effect of personal innovation. The main methodology of this study conducted a survey of users with experience in using Chinese mobile simple payment services, and a total of 309 questionnaires were used as analysis data. The statistical processing of the survey data collected for empirical analysis was conducted using SPSS 26.0. The summary of the research results focusing on the hypothesis test results is as follows. First, it was found that the social impact, economic feasibility, and mobility of the mobile simple payment system all had a significant positive (+) effect on the perceived value. Second, it was found that the perceived risk and complexity of the mobile simple payment system had a significant negative (-) effect on the perceived value. Third, the perceived value of the mobile simple payment system was found to have a significant positive (+) effect on the intention to continue use. Fourth, the perceived value of the mobile simple payment system was found to strengthen the positive (+) effect of mobility on the perceived value among the factors of benefits of the mobile simple payment system, and the negative (-) effect of complexity on the perceived value was alleviated. Focusing on the results of this study, the following implications were presented. It is believed that Chinese mobile simple payment system operators should strive to secure more users to strengthen social values, convenient systems, personal information protection, simplify systems, and provide innovative services.
Modernization Challenges and Development Proposals from Chinese Cabbage Logistics at Garak Wholesale Market
Authors:   The Korean Logistics Research Association, Yoon Duk-In , Han Gwan-Soon
Published: November 2023

Kimchi is the most traditional side dish, and a staple food for the average Korean table. Cabbage, the primary ingredient for Kimchi, is consequently the most widely consumed vegetable in Korea. It holds a pivitol role in the nation’s food culture and deeply influences the dietary habits of its citizens, both at home and when dining out. The distribution of cabbage in wholesale markets traditionally involved harvesting them from the fields, packaging them in bulk bags, loading them onto general cargo vehicles, and then transporting them to Garak Market. Once there, the cabbages often remained at auction sites for extended periods until they were sold. This led to various issues, such as diminished product value, increased market congestion, distribution delays, and escalating logistical costs. Furthermore, given that cabbages direct to Garak Market constitutes 24.2% of the nation’s total wholesale market volumes, there’s a pressing need to refine and modernize its logistical system. Considering these challenges, the government plans to initiate an online wholesale market for agricultural products by the end of 2023. This will also involve introducing an electronic delivery system intended to be rolled out gradually across all national public wholesale markets. However, for this endeavor to succeed, the preliminary steps of palletizing wholesale market products in essential.
This research delves into the distribution and logistics of cabbage from its cultivation to the wholesale market. It pinpoints issues in the current logistics practices and evaluates the economic viability of pallet shipping and unloading. With a B/C Ratio of 1.31, the analysis confirms its economic feasibility. The study champions the advancement of palletization in wholesale markets, which is projected to enhance the logistical efficiency significantly, aligning with the government’s drive to digitalize and modernize the nation’s public wholesale markets.
Prognostic role of PD-L1 and P53 proteins in oropharyngeal squamous cell carcinoma depending on the status of the human papilloma virus
Authors: Polatova D.  Sh. , Gildieva М.  S. , Madaminov A.  Yu. , Savkin A. V. , Sklyarov D.  S.
Published: November 2023

Background: At a time lots of cases of HPV associated oropharyngeal squamous cell carcinoma (HPV + OPSCC) are on the rise and excellent outcomes are seen when comparing HPV-OPSCC, identification of HPV status has become a powerful and widely used marker. Despite this, 20–25 % of HPV + OPSCC patients relapse within 3 years. The most significant barrier to identifying patients at high risk of relapse and death is the lack of clinically useful prognostic markers.

Methods: The study included 62 patients treated with OPSCC T1–4N0–3M0 (7th edition, AJCC) in 2015–2020 in clinics located in two large cities of Uzbekistan (Tashkent and Samarkand). The study analyzed the prognostic value of PD-L1 and p53 proteins in OPSCC, taking into account HPV status. In addition, the relationship between PD-L1, p53 and HPV status was analyzed, as well as their impact on patient survival.

Results: Positive HPV status with positive PD-L1 expression improves overall survival of patients compared to their negativity (p = 0.261). The mutant type of p53 protein has a negative correlation with HPV status, which reduces survival time (p < 0.001). Wild type p53 is detected in a small number of patients, but it shows a positive correlation with HPV status as a strong protective factor that reduces the risk of death (p = 0.01).

Conclusion: Positive HPV status is not always a reliable predictor of risk stratification for patients with OPSCC, because additional indicators associated with the development of OPSCC need to be identified to reinforce the value of predictive predictors other than HPV status.
Pharmacoeconomic evaluation of the accelerated recovery and blood saving program in extended combined operations on the pelvic organs
Authors: Lyadov V. К. , Garipov М. R. , Moskalenko A. N. , Kornev D.  О. , Feoktistov D.  V. , Polushkin V.  G. , Bulanov А.  Yu. , Ayupov R.  Т. , Galkin V.  N.
Published: November 2023

Background: The newly diagnosed pelvic cancer appears to be locally advanced in every third patient, which requires a comprehensive approach to treatment and often extensive combined surgical interventions. Long duration of operations, blood loss, complications of the tumor process during or after previous treatment often lead to the development of complications, slow rehabilitation and increasing cost of treatment. The use of fast track protocol (FTP) and blood-saving technologies can reduce the impact of these adverse factors.

Aim: The evaluation of the pharmaco-economic efficiency of fast track protocol and blood-saving technologies in patients after extended combined operations for pelvic tumors.

Materials and methods: The study included 111 patients with pelvic tumors who underwent an extensive combined surgery for rectal or gynecological tumors. Among them, 52 patients were underwent the same fast track protocol with a focus on the use of blood-saving technologies (2020–2021), the management of patients in the control group was more conservative (n = 59, 2018–2019). After analyzing the factors affecting the treatment outcomes, 2 groups of 16 patients comparable in basic clinical indications were formed by selection of pairs patients using quasi-randomization to assess the direct costs of treatment.

Results: The cost of treatment in the FTS group and the control group was 157744 ± 32728,72 and 273429 ± 217931,5 (P < 0,05) rubles,  respectively. The lower blood loss (206 ± 70 ml vs 430 ± 208, р = 0,3) allowed for a statistically significant difference in the frequency of transfusion of blood components (2 vs 12, p < 0,0009), despite the higher cost of supplies in the FTS group (132913 vs 57347 rubles). Also, the resuscitation bed-day (1,75 ± 1,3 vs 3,5 ± 2, р = 0,5) and the postoperative bed-day (16,8 ± 8; 8–32; vs 27 ± 18, р = 0,6) were lower in the FTS group.

Conclusion: According to our data using the fast track protocol and blood-saving technologies in a group of patients with locally extensive pelvic organs tumors has helped to reduce the cost of treatment and improve the efficiency of the hospital.
Clinical significance of MET alterations in non-small cell lung cancer and currently available therapies
Authors: Smolin S.  А. , Zhukova L.  G. , Smolin А.  V. , Bubenko D.  N. , Grechukhina К.  S.
Published: November 2023

Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality both in Russia and worldwide. At diagnosis, most patients have advanced disease when the use of local treatment modalities is limited and systemic chemotherapy fails to provide a pronounced and sustained benefit. The advent of targeted therapies has significantly changed the treatment paradigm of NSCLC. Genetic alterations representing potential molecular targets have been identified in up to 60 % of non-squamous NSCLC cases, and agents directed against 50 % oncogenic targets have been approved. Various activat ing mutations of the MET signaling pathway (gene amplifications and alterations) associated with unfavorable disease outcomes occur in 2–4 % of NSCLC patients. Recently, significant advances in the development of therapies targeting this signaling pathway have been made. The article provides an overview of the key studies evaluating novel therapeutic options for NSCLC with MET alterations.
The choice of treatment for chemorefractory colon cancer
Authors: Cheporova M.  S. , Cheporov S.  V. , Tryakin A. A.
Published: November 2023

Metastatic colorectal cancer (mCRC) is a major challenge in the treatment of malignant neoplasms. However, with the development of cytotoxic chemotherapy, targeted therapy and local therapies, survival rates have improved significantly. Treatment of patients with CRC in the third and subsequent lines of therapy suggests the use of regorafenib / TAS102, as well as a return to previously used chemotherapy. Late-line treatment with anti-EGFR antibodies (cetuximab, panitumumab) is the choice for mCRC as it has been shown to improve survival rates. BRAF inhibitor and an anti-EGFR antibody is effective in BRAF mutations. A feature of the HER2 / neu mutation is the requirement for dual blockade with trastuzumab + lapatinib or pertuzumab + trastuzumab. For MSI-high, anti-PD therapy (nivolumab, pembrolizumab, or nivolumab + ipilimumab combination therapy) is highly effective. Adagrasib and sotorasib have demonstrated their value in the treatment of CRC with the KRAS G12C mutation. Two inhibitors are approved for NTRK-positive colorectal cancer — larotrectinib and entrectinib. It is also worth noting that one of the local options for the treatment of mCRC is stereotactic radiation therapy. This article presents the current possibilities of therapy for chemoresistant CRC.
Successful surgical treatment of chemoresistant mediastinal germ cell tumor
Authors: Khakimov G.  A. , Khakimova G.  G.
Published: November 2023

Mediastinal teratoma is a rare germ cell tumor. The mediastinum is the most common extragonadal site. Malignant tumors of the mediastinum account for 4 % of all extragonadal tumors of the mediastinum. We present a case of successful surgical treatment of a 24‑year-old man with a gigantic immature mediastinal teratoma complicated by severe cardiorespiratory disorders.
Evaluación del sistema de costeo de la Panadería Trillos en los factores que intervienen directamente en la determinación de los costos de producción
Authors: Rodriguez Laura Nathalia , Guadrón López Alfonso Enrique , Dallos Jenifer Tatiana , Ardila Karen Johana
Published: November 2023

La panadería es un arte, que lleva miles de años de ejercicio y ha estado presente en la evolución y transformación de nuestras sociedades. Es a través de este oficio, que se obtiene el pan, el cual es considerado sinónimo de alimento en muchas culturas y hace parte de la dieta alimentaria y forma de expresión cultural y religiosa en muchos pueblos del mundo. La panaderíá y su ejercicio, al igual que las técnicas de fabricación y los ingredientes utilizados para la elaboración del pan, el cual se puede analizar su proceso, su sistema de costeo y rentabilidad.
Evaluación del sistema de costeo por procesos de la finca Villa Sofía en los factores que intervienen directamente en la determinación de los costos de producción
Authors: Torres Sierra Karim Daniela
Published: November 2023

La FINCA VILLLA SOFIA, es una finca cafetera que lleva aproximadamente 5 años de producción, es una finca que cuenta con 13 hectáreas de las cuales 10 hectáreas están sembradas en café́, cuenta con dos certificaciones las cuales son Rainforest certificado por la Federación Nacional de Cafeteros y el sello Practices Certificada por la organización ECOM; estas certificaciones permiten a la finca tener una garantíá de que el café́ es de buena calidad, ofrecen beneficios económicos y sociales. Se está́ implementan un sistema de costeo por procesos para concluir cual es la utilidad dada por esta finca o en su defecto cuál es su perdida.
Caracterización de la cultura del consumo de pescado en la provincia comunera
Authors: Rugeles Salazar Johan Alexis , Cediel Rueda Héctor , Osorio Plata Juan Pablo , Corredor Castillo Adriana Soliris
Published: November 2023

Esta investigació n, se llevó a cabo en la provincia comunera del departamento de Santander. Con el objetivo de caracterizar la cultura de consumo de pescado en los municipios del Socorro, Galán y Palmas del Socorro, determinar la frecuencia de consumo de pescado, identificar la especie de mayor demanda y los motivos de preferencia. Los resultados de este estudio, mostraron que el 71% de los encuestados consume pescado entre 1 y 4 veces al mes. Ası́ mismo, se pudo identificar que la especie de preferencia es la Tilapia Roja (Oreochromis sp) mejor conocida como mojarra seguido por la Cachama (Piaractus brachypomus) y el Bagre. Adicionalmente, la mayorı́a de los encuestados afirmó conocer los beneficios que tiene consumir pescado.
Determinación del método más eficiente en la migración del catión potasio en caolinita analítica sometido a un campo eléctrico uniforme
Authors: Flórez Guzmán María Victoria , Gómez Fernández Sandy Yulieht , González Cuadros Lizzette Viviana , Rodríguez Naranjo Sandra , Almeira Ospina Juan Ernesto
Published: November 2023

Debido a la gran contaminación presente en el suelo por acció n antró pica, se realizó la evaluació n para la remoción de contaminantes del suelo como lo son los metales, a través del sistema de electromigración, el cual consiste en someter iones a diferencial de potencial constante para que estos se transporten al electrodo de carga opuesta. Lo anterior consiste en que los iones de carga positiva (cationes) como el potasio, se transportan hacia el electrodo de carga negativa, y los iones de carga negativa (aniones) se transportan al electrodo de carga positiva. La evaluación de transporte constó de dos métodos, se construyeron dos celdas en acrı́lico iguales que consta cada una de tres cámaras: la primera catiónica, una solución de potasio de 100ppm, en la cámara central caolinita analı́tica y finalmente en la tercera cámara anódica agua desionizada. El primer método se adaptó un sistema de vibración a través de un parlante y el segundo sin vibración. El objetivo de la investigación fue determinar si el método con vibración es más eficiente que el método sin vibración para la migración del catión potasio en caolinita sometido a un debido a que es el que menos energı́a migrar mayor concentración de este.
Fortalecimiento del aprendizaje de la geografía colombiana en estudiantes, incorporando un ambiente virtual de aprendizaje
Authors: Granados Amaya Amparo Milena , Salamanca Leguizamón Carolina , Alba Rojas Cesar
Published: November 2023

La presente investigación surge tras observar que, en el área de Ciencias Sociales de los grados cuarto y quinto, no se está́ implementando una metodologíá apropiada, en la enseñanza de la geografía, generando consecuencias, como por ejemplo la no comprensión de otras temáticas, en los grados superiores. Es así ́como se plantea el objetivo fortalecer el aprendizaje de la geografíá colombiana en los estudiantes de cuarto y quinto grado de la institución Educativa Guane mediante el diseño e implementación de un ambiente virtual de aprendizaje. De esta manera, y con el fin de indagar sobre los presaberes de los estudiantes, en cuanto al dominio de conceptos sobre geografíá colombiana, se hace uso de la investigación acción educativa para realizar una prueba diagnóstica; identificando a la vez, fortalezas y debilidades en el tema. Seguidamente, y con base en las necesidades planteadas por los estudiantes, se diseñó́ de un ambiente virtual de aprendizaje, alternando el uso de herramientas y recursos virtuales educativos, como gestores de conocimiento y aprendizaje. Es de resaltar, que los resultados obtenidos, en su mayoría fueron positivos, ya que, al emplear las TIC en un AVA, se desarrolló́ una experiencia significativa y diferente para los estudiantes. Esta situación propició en los estudiantes una mayor motivación e interés por el aprendizaje de la geografíá de Colombia, acercándolas aun más a la realidad y el contexto.
Alternativa del método de explotación de material pétreo, caso: río Sogamoso parte baja, sector anexo a la central hidroeléctrica Hidrosogamoso
Authors: Lemus Castilla Isabel Cristina , Rojas Silva Josué Alexander
Published: November 2023

La construcción y puesta en funcionamiento de la Hidroeléctrica “Central Hidrosogamoso” (2009), implicó la utilización de 474,6 (m3/s) metros cúbicos por segundo del caudal de la cuenca del río Sogamoso (aprox. el 85% del caudal), lo cual provoco disminución del caudal del río, y a su vez un impacto directo en la producción minera de material de construcción, producto de la ausencia de corrientes rápidas que arrastren el material pétreo, en consecuencia de lo anterior, se forman sedimentos y algo de gravas que salen por las compuertas de la represa, a través del caudal ecológico; mediante una revisión al estado del arte de la producción de material de construcción proveniente de la cuenca del río Sogamoso, se busca determinar cuál es la actual alternativa del método de explotación del material pétreo. Existen títulos mineros expedidos por la Agencia Nacional de Minería-ANM; permisos y concesiones expedidas por la autoridad ambiental regional “Corporación Autónoma Regional de Santander (CAS)”, y un registro que lleva la Autoridad Municipal para la minería de subsistencia. Dentro de la investigación, se pretende revisar: a) las características determinadas en el documento de Manejo y Ordenación de la cuenca del río Sogamoso, b) el Mega proyecto “Central Eléctrica Hidrosogamoso”, c) los sistemas y métodos utilizados para la extracción de los materiales de Construcción, d) de los aspectos legales para las explotaciones sujetas a un título minero y/o otorgadas por acto administrativo de la autoridad ambiental “CAS”, e) métodos que se están aplicando a la explotación artesanal e industrial, f) de los diferentes impactos ambientales y socio-económicos de la minería de subsistencia.
Impacto ambiental de la gestión integral de residuos hospitalarios y la regulación Colombiana
Authors: Patiño Rueda Erika Tatiana , Acevedo Parra José Ignacio
Published: November 2023

Las entidades prestadoras de servicios de salud sean públicas o privadas en el desarrollo de sus actividades hospitalarias generan gran cantidad de residuos peligrosos de carácter hospitalario. De acuerdo, al concepto “los residuos sólidos hospitalarios son aquellas sustancias, materiales, que son el resultado de una actividad ejercida por el generador, que produce residuos relacionados con la prestación de servicios de salud por lo cual se implementa la gestión integral”. (Cristian, 2009). La gestión integral de residuos hospitalarios, es el manejo de los desechos que se producen en las instituciones de salud, desde su generación, separación y disposición final en su gestión interna y externa, los restos hospitalarios son la suma de aquellos desechos que se generan en la atención medica de pacientes como químicos de laboratorio, citotóxicos, desechos cortopunzantes, de riesgo biológico, basuras farmacéuticas así como aquellos que son resultado de la atención diaria como ordinarios, plásticos y reciclables. En esta monografía, se realizó un análisis de las normas y estrategias en la regulación colombiana, en cuanto a la disposición y manejo de los residuos hospitalarios y a su vez se analizó el alcance a escala del impacto ambiental que se genera en una institución prestadora de servicios de salud en Colombia en la gestión integral de desechos hospitalarios.
Impuestos a bebidas alcohólicas en Colombia
Authors:   Universidad Icesi, Maldonado-Vargas Norman , Herrera Juan Camilo ,   Universidad Icesi, Llorente Blanca ,   Fundación Anáas, Marín Alejandro ,   Fundación Anáas
Published: November 2023

Esta nota de política propone el rediseño del impuesto a bebidas alcohólicas, así como otras medidas para potencializar su efecto. Los impuestos selectivos son la medida más efectiva para la reducción del consumo de alcohol y prevención de enfermedades no transmisibles. Esta propuesta se plantea principalmente para la protección de la salud pública pero también tiene efectos positivos en las finanzas públicas.
КОГНИТИВНО-ДИСКУРСИВНЫЙ АНАЛИЗ СИНОНИМИЧНЫХ ГЛАГОЛОВ ПОДДЕТЬ — ПОДКОЛОТЬ — ПОДКОВЫРНУТЬ
Authors:   Санкт-Петербургский государственный университет, Нгок Иен Кхань Ву
Published: November 2023

В статье проводится когнитивно-дискурсивный анализ трех глаголов-синонимов поддеть, подколоть и подковырнуть на материале толковых словарей, а также на обширном языковом материале «Национального корпуса русского языка» (далее — НКРЯ) и контекстов, найденных с помощью свободного поиска в интернет-пространстве. Для анализа были отобраны современные контексты, созданные в последние десятилетия. В ходе исследования рассматриваются инвариантные и вариантные сценарии, стоящие за семантикой каждого глагола, анализируются особенности употребления данных лексем, диапазон действий, вербализуемых синонимичными глаголами. В результате анализа выявляются различия между глаголами поддеть, подколоть и подковырнуть. В качестве основных в работе используются метод компонентного анализа значения, дистрибутивный метод и метод когнитивно-дискурсивного анализа. Полученные данные могут быть использованы при составлении учебного словаря русских синонимов для инофонов.
ЭКСПЛИЦИТНЫЕ СПОСОБЫ ВЫРАЖЕНИЯ ПОЛОЖИТЕЛЬНОЙ МАНИПУЛЯТИВНОЙ КОММУНИКАТИВНОЙ ДЕМОНСТРАТИВНОСТИ
Authors:   Волгоградский государственный технический университет, И. А. Тисленкова
Published: November 2023

Статья посвящена выявлению вербальных и невербальных средств выражения положительной манипулятивной коммуникативной демонстративности. Актуальность выбранной темы обусловлена неизученностью проблемы. В результате исследования устанавливается, что данная тональная разновидность представляет собой эмоционально-стилевую форму воздействия на реципиента, которая отличается преувеличенным позитивным представлением говорящим своего образа, акцентированностью доминирующей конструктивной эмоции, выражаемых средствами семиотической полимодальности. Показано, что манипулятивная демонстративность актуализируется в продуктах речи с помощью применения разнообразных языковых и неязыковых средств. Отмечается, что языковые средства включают речевые стратегии персуазивности и преувеличения, гиперболические мелиоративные тропы-акцентуаторы (эпитеты, сравнения, метафоры, смысловую антитезу, антитезу) и наречия, положительные эпитеты, эмоционально окрашенные фразеологизмы с положительным компонентом, клишированные словосочетания, эмоциональные глаголы с положительной коннотацией, синтаксические конструкции с однородными членами предложения. Неязыковые средства составляют материальные знаки социального престижа, позитивные знаковые элементы поз и движений тела и особенности внешнего вида говорящего.
ХЕЗИТАЦИОННЫЕ ЯВЛЕНИЯ В РУССКОМ УСТНОМ МОНОЛОГЕ-РАССКАЗЕ КИТАЙЦЕВ В ЗЕРКАЛЕ СОЦИО- И ПСИХОЛИНГВИСТИКИ
Authors:   Санкт-Петербургский государственный университет, Цзэли Чжао
Published: November 2023

Статья посвящена анализу с социально-психологической точки зрения хезитационных явлений (ХЯ) в русском устном монологе-рассказе китайцев. В статье устанавливается связь ХЯ в таком монологе с социально-психологическими характеристиками говорящего (пол, уровень владения русским языком и психотип), а также определяется, какие из этих характеристик оказывают наибольшее влияние на появление ХЯ в устном монологе. Источником материала для анализа послужили 20 русских монологов-рассказов на тему «Как Вы проводите время на каникулах?» из корпуса «Сбалансированная аннотированная текстотека» (САТ), созданного и разрабатываемого в Санкт-Петербургском государственном университете. Проведенный анализ показал наличие корреляции между уровнем владения информантами русским языком и их социально-психологическими характеристиками, с одной стороны, и появлением ХЯ в их речи, с другой. При этом выяснилось, что уровень владения русским языком наибольшее влияние оказывает на частоту появления ХЯ, а психологические характеристики информантов — на тип ХЯ.
ПУСТОТА В ПРОСТРАНСТВЕ ЛИНГВОКУЛЬТУРНЫХ ЦЕННОСТЕЙ (НА МАТЕРИАЛЕ БУРЯТСКОГО ЯЗЫКА)
Authors:   Бурятский государственный университет имени Доржи Банзарова, Е. А. Бардамова , Д. Ш. Харанутова ,   Бурятский государственный университет имени Доржи Банзарова
Published: November 2023

Статья посвящена анализу средств объективации пустоты в бурятском языке в аспекте аксиологической картины мира. Установлена специфика восприятия и наделения описываемого фрагмента пространства окультуренными идеями о связи объектов и явлений и их свойствах в реальной действительности. Анализ массива текстов Бурятского корпуса позволяет прийти к выводу, что инвариантный признак пустоты ‘отсутствие наполненности’ формирует ряд оценочных смыслов, функционирующих в виде установок, в основе которых признание достоинств и недостатков предметов, характеризуемых посредством признака пустоты. Рассмотренные лингвокультурные ценности имеют иллокутивный эффект в силу транслируемых приоритетов, формирующих маркеры значимости бытия. Автором выявлено, что пустота внешнего мира воспринимается как локус неблагоприятных условий бытия для реализации витальных потребностей. Появление подобной негативной аксиологии обусловлено пониманием того, что данный фрагмент пространства лишен привычного порядка и определенности. Для ценностной ситуации духовного мира человека в бурятском языке пустота выступает символом неосновательности, бесплодности действий и мыслей, никчемности, бессмысленности, пустословия, голода и нищеты.
Traumatic injury of the ulnar artery and ulnar nerve: clinical case report
Authors: Tavata Lizbeth Daza Villa , Jose Luis Villareal Salgado , Victor Hugo Grano Gonzalez , Victor Gibran Reyes Garcia , Jose de Jesús Vargas Montes , Gustavo Emmanuel Garcia Marin , Sergio E. Vazquez Lara , Mayra Yilzett Reyes Gutierrez , Ana Laura Ramirez Soto , Antonio Magallón Gómez
Published: November 2023

Traumatic injuries to upper extremities cause vascular and nerve injuries, which is why they constitute a cause for attention in the emergency service of medical units. These injuries can cause sequelae that can affect people's quality of life and their daily activities if they are not managed appropriately, so it is necessary to have knowledge of the anatomy to provide individualized therapeutic management. Therefore, we present the case of a female patient who suffers a traumatic injury to the forearm, which causes ulnar arterial and nerve injury. Exposing the management provided in our institution and its results.
The treatment for closure of the bladder neck via transvaginal approach
Authors: Castro Alejandra A. , Gonzalez Guillermo A. , Gomez Andrea M. , Santiago Gerardo G. , Perez Mariano B. L. , Quevedo Mauricio M. , Alba Maria P. , Cuellar Rodrigo M.
Published: November 2023

Urinary incontinence is described as the involuntary loss of urine due to an increase in intra-abdominal pressure combined with a lack of contraction of the detrusor muscle. The most common being stress incontinence, as it occurs in 30% of women between 30 and 60 years old. There is another condition called hidden stress incontinence as a result of a coiling of the urethra that causes obstruction in its lumen. This can manifest itself when performing any activity that involves effort, such as coughing or sneezing. Nowadays there are numerous surgical interventions for the treatment of these pathologies, so there is a discrepancy in the choice of the appropriate surgical technique to correct these conditions in isolation.
El planeamiento educativo en la era de la big data: nuevas perspectivas para viejos (e irresueltos) desafíos
Authors: Morduchowicz Alejandro , Suasnábar Juan
Published: November 2023

¿Qué es planificar la educación hoy? Mejor dicho, ¿qué podría ser? Para la primera hay unas cuantas respuestas posibles, pero para la segunda sería difícil encontrar más de un par. El planeamiento educativo atravesó distintas etapas, pero parecería que lo único que sobrevive en las áreas dedicadas al tema es poco más que el planeamiento clásico. Cuando se hace, se sustenta en los sistemas de información de los ministerios de educación y las áreas de estadísticas gubernamentales. De las actividades que solían hacerse, lo que ha quedado (a veces ni eso) son las tareas de proyección -de alumnos, de docentes, de escuelas- y de asesoramiento sobre la base de esas estimaciones o de la recolección de información competente a esas oficinas.
Research Insights: Why Doesn't Entry of Larger and More Productive Firms Drive Out the Many Small Firms in Developing Countries?
Authors: Talamas Marcos Miguel Ángel
Published: November 2023

An expansion from zero to the average number of chain stores in a Mexican neighborhood (6.7) reduces the number of neighborhood shops by 15%. This reduction is not driven by increased shop exits but by decreased shop entries. Shops retain their sales of fresh products and 96% of their customers, but customers visit shops less often and spend less on non-fresh and packed goods. Shops survive by exploiting comparative advantages stemming from being small and owner-operated, such as lower agency costs, building relationships with the community, having a broader and tailored product mix, and offering informal credit.
Research Insights: Can Electoral Incentives Explain Gender Differences in Leaders' Behavior?
Authors: Chauvin Juan Pablo , Tricaud Clemence
Published: November 2023

Female and male mayors in Brazil responded differently to the COVID-19 crisis, with effects on mortality that varied over time. In the early months of the pandemic, female-led municipalities were less likely to close essential businesses and had higher COVID-19 death rates compared to male-led municipalities. Towards the end of the year 2020, however, female-led municipalities were more likely to close essential businesses and had fewer COVID-19 deaths than male-led municipalities. This suggests that female and male mayors handled the crisis in distinct ways, with implications for understanding gender differences in policymaking and crisis management.
Research Insights: How Can the Full Potential of Telemedicine Be Unlocked?
Authors: González María P. , Scartascini Carlos
Published: November 2023

An intervention in Argentina that sent periodic emails to households about available telemedicine services effectively increased the adoption of and demand for telemedicine. Patients who were part of the intervention were significantly more likely to use telemedicine services. The number of virtual consultations by the group that received the email intervention was six times larger than those of the control group after eight months. The study found that the intervention had lasting effects, suggesting that getting patients to try telemedicine for the first time can lead to continued use over time.
Carbono en el Pacífico sudamericano: reservas en comunidades vegetales de un humedal costero en Perú
Authors: Chavez Ronal , Aponte Héctor
Published: November 2023

Los humedales costeros brindan diversos servicios ecosistémicos, entre ellos, el almacenamiento de carbono. En este estudio se cuantificó la reserva de carbono en las principales comunidades vegetales del humedal de Santa Rosa (Lima, Perú). Para ello, se hicieron 36 parcelas de 0,25 m2 en las que se recolectó biomasa vegetal aérea y suelo en dos profundidades (0-10 cm; 10-20 cm). Posteriormente se cuantificó el porcentaje de carbono en las muestras y se escaló en función del área de cada formación vegetal. La cantidad de carbono almacenado en las comunidades de Thypha domingensis (totoral), Schoenoplectus americanus (juncal) y de vega mixta fueron 76,61 ± 26,87 TnC/ha, 75,29 ± 39,85 TnC/ha y 63,96 ± 25,81 TnC/ha, respectivamente, con un total entre estas tres comunidades de 2.703,02 TnC, que equivalen a 9,920,07 TnCO2, valorizadas entre $4960 y $496.000 en el mercado voluntario mundial de carbono. Los resultados obtenidos, muestran la importancia ambiental y económica que este humedal tiene.
Sidney Tompkins: “La salud mental se trata de un asunto que va más allá del trabajo periodístico”
Authors: Cruz Pamela J. , Samson Eric
Published: November 2023

Por más de 40 años, Sidney ha ejercido la psicoterapia clínica para niños, adultos, parejas y profesionales, por cerca de 45 años. Junto a su esposo, Al Tompkins, quien es profesor senior del Instituto Poynter, ha trabajado con periodistas de todo el mundo quienes han sufrido estrés traumático. De manera reciente, ambos lo han hecho con reporteros ucranianos y rusos quienes han cubierto los enfrentamientos bélicos que empezaron el 24 de febrero del 2022.
Periodismo: innovación, resiliencia, reinvención
Authors: Castellanos Santiago
Published: November 2023

El título de este número de #PerDebate, Resiliencia e innovación: narrativas inmersivas, nuevos formatos y modelos económicos en tiempos de crisis, una vez más subraya la necesidad del periodismo de reflexionar sobre las condiciones que han provocado su crisis en las sociedades actuales. Tal y como lo conocemos hoy en día, el periodismo surge en un contexto de modelos epistemológicos, tecnológicos, comunicacionales y de negocio típicos de la modernidad y del capitalismo de las democracias liberales del siglo XIX y XX. Si ese contexto cambia, tal y como ha venido sucediendo desde finales del siglo XX y con más intensidad en el siglo XXI, no es de extrañar que el periodismo haya entrado en crisis. Conceptos típicamente modernistas como verdad u objetividad, que fueron paradigmáticos en la modernidad, se han cuestionado desde hace décadas en las humanidades y en las ciencias sociales.
SORPTION OF SCANDUIUM AND YTTRIUM COMPOUNDS BY ZIRCONIA-SILICA NANOSORBENT
Authors: Perlova O. V. , Ovcharenko A. O. , Shуrykalova A. O.
Published: November 2023

Physical and chemical regularities of sorption extraction of scandium and yttrium compounds from (0.1–2.5)∙10-4 M aqueous solutions by zirconium-silica nanosorbent with specific surface area of 900-1000 m2/g, pore radius of 3.5-7, 6 nm and with a ZrO2 content of 29% have been established. It is shown that the studied sorbent efficiently (>99%) removes scandium and yttrium at pH 8 – 10 (Sc) and pH 9 – 10.5 (Y) and at sorbent consumption of 0.4 g/dm3. The time to reach sorption equilibrium is 240 min (Sc) and 210 min (Y). Modeling of scandium and yttrium sorption kinetics by Boyd’s external diffusion and internal diffusion models shows that sorption takes place in a mixed diffusion mode. The values of sorption rate constants (0.018 min-1 Sc, 0.033 min-1 Y), external mass transfer constants (4.74 ∙ 10-8 m/min Sc, 8.51 ∙ 10-8 m/min Y) and internal diffusion rate constants (0.0099 min-1 Sc, 0.0093 min-1 Y) have been calculated. It is established that the kinetics of sorption follows the pseudo-second-order model. It is shown that the sorption isotherms of both investigated metals are described by Freundlich, Frumkin-Fowler-Guggenheim and Dubinin-Radushkevich models. The constants of sorption isotherm models, characteristic energy of sorption (10.79 kJ/mol Sc, 9.58 kJ/mol Y), ΔG0 of sorption (-32.82 kJ/mol Sc, -30.77 kJ/mol Y) are calculated. The results of calculations indicate a significant affinity of scandium and yttrium compounds for this sorbent, spontaneous nature of the process and mixed nature of sorption with a predominance of chemisorption, a significant contribution of ion exchange to the sorption mechanism.