bluuebunny/crossref_metadata_2025 huggingface dataset:
Book Review: Nature is Nurture
Authors: Beaver Laura
Published: January 2025

N/A
Defining Welcome: Lesbian, Gay, Bisexual, and Genderqueer Christian Voices
Authors: Cline Craig , Garzón Hampton Amy
Published: January 2025

Christian congregations’ approaches to people who are lesbian, gay, bisexual, transgender, or queer (LGBTQ+) have been influenced by non-affirming interpretations of several Bible verses. Consequently, for many LGBTQ+ Christians, religious spaces have been unwelcoming and negatively affected their well-being. Recently, many prominent Christian denominations have re-examined their approaches to LGBTQ+ Christians in light of different interpretations of scripture and a recognized need to create welcoming religious spaces for LGBTQ+ people. This study explored the concept of welcome in religious settings from the standpoint of lesbian, gay, bisexual, and genderqueer Christians. Participants reflected on their experiences with unwelcome in religious settings and what welcome has meant for them in LGBTQ+ affirming churches. The experience of welcome emerged through four themes – safety, visibility, audibility, and opportunity. Implications for ministry and social work practice are considered. Guidance for LGBTQ+ Christians undergoing a faith transition are also presented.
Which way?
Authors: Szto Peter
Published: January 2025

not applicable
Perspectiva de la Eficiencia en los Servicios de Mantenimiento Postventa para Vehículos Tipo L3.
Authors: Campoverde Reinoso Irvin , Villao Morán Andrés , Noroña Merchán Marco
Published: January 2025

Optimizar los procesos de mantenimiento en vehículos L3 es crucial para asegura las satisfacción del cliente y mejorar la rentabilidad empresarial.
Para analizar ésta situación, se empleó técnicas de investigación incluyendo estudios de caso, entrevistas a clientes y análisis de datos. La investigación recopiló información sobre los principales problemas y desafíos que enfrentan los servicios de mantenimiento postventa, así como las mejores prácticas y estrategias que han adquirido las empresas líderes del sector.
Con base a los resultados obtenidos, se ha podido evidenciar que uno de los mayores desafíos para mejorar la eficiencia de estos servicios es la falta de coordinación y comunicación efectiva entre los distintos departamentos involucrados; además, se identificaron áreas de mejora en la capacitación del personal, la gestión de inventarios y la implementación de tecnologías avanzadas en los procesos de mantenimiento.
Con estos hallazgos, se propone una serie de recomendaciones para incrementar la eficiencia en los servicios de mantenimiento postventa para vehículos tipo L3, lo que incluye la implementación de sistemas de gestión integrados, la capacitación continua del personal, la optimización de la logística de repuestos y la adopción de tecnologías de vanguardia, siendo una de las principales la inteligencia artificial y el análisis de datos.
Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations
Authors: Ren Zhiyang , Tang Shuhan , Wang Jia , Lv Shuqing , Zheng Kai , Xu Yong , Li Ke
Published: January 2025

As a complex and dynamically regulated process, wound healing is collaboratively carried out by multiple types of cells. However, the precise mechanisms by which these cells contribute to immune regulation are not yet fully understood. Although research on bone regeneration has been quite extensive, the application of bioactive glass (BG) in skin tissue repair remains still relatively underexplored. The review focuses on the principles and the latest progress of using BGs for skin tissue repair, highlighting BGs’ special performance requirements, including biological activity, biocompatibility, biodegradability, and antibacterial properties, emphasizing their potential for skin tissue repair. In addition, BGs play a substantial role in regulating various inflammatory cells (neutrophils, macrophages, mast cells, etc.) and tissue repair cells [fibroblasts, vascular endothelial cells, mesenchymal stem cells (MSCs), etc.] involved in wound healing. The review also covers recent developments in composite materials incorporating BGs, demonstrating their ability to promote angiogenesis, inhibit wound biofilms, and improve inflammatory responses in chronic wounds. Furthermore, BGs have shown effectiveness in promoting epithelial regeneration and collagen deposition in burn wounds as well as their applications in scar management and post-tumor resection wound care. Finally, we summarize our views on challenges and directions in the emerging field of BGs for skin tissue regeneration research in the future.
Isoprenaline-Modified Polyethyleneimine as an Efficient Gene Delivery System for Targeted Asthma Therapy and Airway Remodeling Inhibition
Authors: An Jiwon , Choi Moonhwan , Kim Sol , Yoon Hyungkyung , Jang An-Soo , Lee Sang-Kyung , Rhim Taiyoun
Published: January 2025

This study introduces a novel gene delivery system, polyethyleneimine modified with isoprenaline (PEI–isoprenaline), to enhance targeted gene delivery in the context of asthma therapy and airway remodeling. In vitro investigations used Beas2B cells to assess the biocompatibility of isoprenaline, PEI–isoprenaline, and small interfering RNA (siRNA)/PEI–isoprenaline complexes, with cytotoxicity evaluations confirming their safety. The transfection efficiency of the siRNA/PEI–isoprenaline complex was scrutinized in THP-1 cells and displayed superior performance in delivering siRNA to cells expressing the β2 adrenergic receptor (ADRB2). In vivo studies used a murine chronic asthma model to evaluate gene delivery to ADRB2-expressing cells in bronchoalveolar fluid and lung tissues. Therapeutic effects were comprehensively assessed through cell analyses, revealing substantial reductions in airway inflammatory cells and fibrosis, particularly in the Arg1 siRNA/PEI–isoprenaline group. The siRNA/PEI–isoprenaline complex exhibited an impressive 80% delivery rate, greatly surpassing the performance of polyethyleneimine 2K (20%). Notably, the complex achieved a substantial 63% reduction in arginase-1 gene expression, validating its therapeutic potential. Noteworthy inhibitory effects on airway hyperresponsiveness were observed, underscoring the complex’s potential as a targeted gene delivery system for asthma treatment. Our findings underscore the promise and effectiveness of the PEI–isoprenaline complex as a gene delivery system, with its demonstrated biocompatibility, transfection efficiency, and therapeutic outcomes, including arginase-1 gene knockdown and mitigation of airway inflammation and fibrosis, indicating it as a promising candidate for advancing asthma therapy and contributing to the understanding and control of airway remodeling in respiratory diseases.
Experimental Investigations on Accelerated Solar Evaporation for Management of Concentrated Saline Liquor
Authors: Veeravel V. , Sathish G. , Nishanthi R. , Kumaresan G. , Srinivasan S.V.
Published: January 2025

Solar energy is an important energy sector that plays a crucial role in reducing greenhouse emission in different industrial sectors, including the leather sector, to control the pollution. Stringent environmental regulations of Zero Liquid Discharge (ZLD) in Indian tanneries are implemented as directed by regulatory authorities. The ZLD system resulted in the generation of saline rejected from membrane systems being evaporated by spending considerable energy. In this paper, the potential of solar energyfor evaporation of reject from ZLD in a closed accelerated solar dryer has been investigated. In this study, the evaporation of reject/ saline water using a solar dryer with different volumes has been experimented and the volume reduction and increase in Total Dissolved Solids (TDS) are monitored during the drying period. It is evident that the closed accelerated solar dryer has shown an increase in evaporation rate with reduction in the volume of water in a given area. The outcome of this study would lead to avoidance of mechanical evaporators in case of smaller capacity ZLD plants and also reduce the amount of water to be evaporated in the Multiple Effect Evaporator (MEE) in case of larger ZLD plants. By the application of the accelerated solar dryer for the evaporator, the potential CO2 emission reduction due to replacement of different fuels used for evaporation of reject has been estimated to reduce the carbon footprint and to ensure the sustainability of the leather industry.
Strategi Penguatan Jurnal untuk Indeksasi Directory of Open Access Journals (DOAJ)
Authors: Hidayat Arip , Andriyana Andriyana , Jaelani Asep Jejen
Published: January 2025

AbstrakDirectory of Open Access Journals (DOAJ) menetapkan serangkaian standar untuk memastikan bahwa jurnal yang terdaftar memenuhi kriteria kualitas dan transparansi yang tinggi. Standar ini mencakup menu minimal yang harus disertakan pada situs web jurnal, seperti kebijakan akses terbuka, tujuan dan ruang lingkup, daftar anggota dewan editorial, pedoman untuk penulis, proses editorial, syarat lisensi, syarat hak cipta, biaya penulis, dan detail kontak. Jurnal Anafora memerlukan perbaikan di beberapa aspek, termasuk penerapan lisensi Creative Commons Attribution-ShareAlike (CC-BY-SA), penambahan anggota dewan editorial, dan penyempurnaan bagian "Tentang" untuk memenuhi persyaratan DOAJ. Implementasi saran ini akan meningkatkan transparansi, kualitas publikasi, dan kepercayaan dalam komunitas akademik, serta memastikan bahwa Anafora dapat memenuhi standar internasional untuk jurnal ilmiah. Abstract The Directory of Open Access Journals (DOAJ) establishes a set of standards to ensure that registered journals meet high quality and transparency criteria. The standard includes minimal menus that must be included on a journal website, such as open access policies, purpose and scope, a list of editorial board members, guidelines for authors, editorial processes, licensing terms, copyright terms, author fees, and contact details. Anafora Journal needs improvements in several aspects, including the implementation of the Creative Commons Attribution-ShareAlike (CC-BY-SA) license, the addition of editorial board members, and the enhancement of the "About" section to meet DOAJ requirements. The implementation of these suggestions will improve transparency, publication quality, and trust in the academic community, as well as ensure that Anafora can meet international standards for scientific journals
Pelatihan dan Sosialisai Sistem Teknologi Digital Kartu Pemegang Senjata Api
Authors: Sutono Sutono , Agustiana Kamil Aditya , Musrifah Ai
Published: January 2025

Abstrak Teknologi dan informasi semakin mengalami kemajuan, salah satunya penggunaan sistem digital semakin meresap ke berbagai bidang kehidupan, termasuk dalam pengelolaan kepemilikan senjata api di lingkungan kepolisian. Saat ini, kartu pemegang senjata api di Polres Cianjur masih menggunakan sistem berbasis kertas konvensional, yang rentan terhadap kerusakan, kehilangan, dan biaya pencetakan. Situasi ini menimbulkan berbagai masalah dalam penyimpanan dan pengelolaan kartu-kartu tersebut. Teknologi digital, yang menawarkan kualitas dan efisiensi dalam pengelolaan data, dapat menjadi solusi yang efektif. Kartu digital, sebagai bentuk virtual dari kartu fisik, memungkinkan informasi disimpan dengan aman dan dapat diakses melalui perangkat elektronik. Penerapan kartu digital di Polres Cianjur akan meningkatkan efisiensi, keamanan, dan kecepatan akses informasi bagi personel yang memegang senjata api. Sistem digitalisasi ini akan mengelola dan menampilkan kartu pemegang senjata api melalui aplikasi berbasis web. Pengabdian ini bertujuan untuk merancang dan mengembangkan sistem teknologi digital untuk kartu pemegang senjata api di Polres Cianjur, dengan harapan dapat mengatasi masalah yang ada dan meningkatkan efisiensi operasional di lingkungan kepolisian. Abstract Technology and information are progressing, one of which is the use of digital systems increasingly permeating various fields of life, including in the management of firearms ownership in the police environment. Currently, firearm holder cards at Cianjur Police Station still use a conventional paper-based system, which is vulnerable to damage, loss, and printing costs. This situation creates various problems in the storage and management of these cards. Digital technology, which offers quality and efficiency in data management, can be an effective solution. Digital cards, as a virtual form of physical cards, allow information to be stored securely and accessible through electronic devices. The implementation of digital cards at Polres Cianjur will improve efficiency, security, and speed of access to information for personnel holding firearms. This digitisation system will manage and display firearm holder cards through a web-based application. This service aims to design and develop a digital technology system for firearm holder cards at Polres Cianjur, with the hope of overcoming existing problems and increasing operational efficiency in the police environment.
Pengembangan Sistem Informasi Reservasi untuk Meningkatkan Kemudahan dan Profesionalisme Berbasis Teknologi di Sektor Pariwisata
Authors: Pratomo Adi , Fitriani Fitriani , Mutammimah Heppy
Published: January 2025

AbstrakKegiatan pengabdian ini bertujuan untuk mengembangkan sistem reservasi kamar berbasis web di Desa Teluk Tamiang, guna meningkatkan efisiensi dan daya saing sektor pariwisata lokal. Permasalahan yang dihadapi meliputi sistem reservasi manual yang tidak efektif dan keterbatasan akses teknologi oleh pengelola. Metode yang digunakan mencakup analisis kebutuhan, desain sistem berbasis model waterfall, implementasi, serta pendampingan berupa pelatihan teknis kepada 15 peserta yang terdiri atas staf desa dan pengelola penginapan. Evaluasi dilakukan melalui survei kepuasan pengguna dan pengamatan langsung terhadap implementasi sistem. Hasilnya menunjukkan peningkatan keterampilan teknis pengelola hingga 70%, serta kemudahan operasional yang berdampak pada peningkatan pemesanan kamar hingga 30%. Sistem yang diimplementasikan melalui domain resorts.teluktamiang.com telah memberikan nilai tambah ekonomis dan diharapkan mampu mendukung perkembangan pariwisata desa secara berkelanjutan. Abstract This service activity aims to develop a web-based room reservation system in Teluk Tamiang Village, in order to improve the efficiency and competitiveness of the local tourism sector. The problems faced include an ineffective manual reservation system and limited access to technology by managers. The methods used included needs analysis, system design based on the waterfall model, implementation, and assistance in the form of technical training to 15 participants consisting of village staff and inn managers. Evaluation was conducted through a user satisfaction survey and direct observation of the system implementation. The results showed an increase in the manager's technical skills by 70%, as well as operational ease that resulted in an increase in room bookings by 30%. The system implemented through the domain resorts.teluktamiang.com has provided economic added value and is expected to support the development of village tourism in a sustainable manner.
Pendampingan dan Penyuluhan Teknologi Pemesanan Jasa Penitipan Anak Melalui Aplikasi Daycare Berbasis Web
Authors: Syafariani R Fenny , Rohmawati Tatik , Susanti Sussy , Sitanggang Andri Sahata , Sari Febilita Wulan , Melian Lusi
Published: January 2025

Abstrak Tujuan kegiatan pengabdian ini adalah melakukan penerapan teknologi kepada daycare dalam meningkatkan pelayanan anak kepada orang tua yang membutuhkan penitipan anak dan menjadikan contoh teknologi pada daycare lain dalam penerapan teknologi dan memperluas informasi tempat pelayanan anak kepada masyarakat/orang tua. Oleh karena itu, tim Universitas Komputer Indonesia melakukan pelatihan dan pendampingan teknologi berupa aplikasi pelayanan penitipan anak berbasis web untuk memudahkan dalam mendapatkan informasi dan layanan/fasilitas penitipan anak. Metode yang digunakan dalam kegiatan pengabdian ini menggunakan pendekatan diskusi/dialog, mengajukan beberapa pertanyaan, kemudian membuat solusi dengan pendekatan teknologi. Metode ini dilakukan dengan alasan latar belakang pendidikan orang tua yang berbeda-beda sehingga mempengaruhi pengetahuan intervensi/teknologi. Aplikasi web ini memiliki fungsi registrasi, penggunaan fasilitas/pelayanan, penilaian anak, serta fungsi pembayaran. Hasil dari kegiatan pengabdian ini meningkatkan pelayanan daycare dengan dukungan teknologi, informasi tempat penitipan anak, dan meningkatkan kepercayaan masyarakat/orang tua kepada tempat penitipan anak. AbstractThe purpose of this service activity is to apply technology to daycare in improving children's services to parents who need child care and to make an example of technology in other daycare in applying technology and expanding information on children's services to the community / parents. Therefore, the Universitas Komputer Indonesia team conducted training and technology assistance in the form of a web-based daycare service application to make it easier to get information and daycare services/facilities. The method used in this service activity uses a discussion/dialogue approach, asking several questions, then making solutions with a technological approach. This method is carried out due to the different educational backgrounds of parents which affect the knowledge of intervention/technology. This web application has a registration function, facility/service usage, child assessment, and payment functions. The results of this service activity improve daycare services with technological support, daycare information, and increase public/parental trust in daycare.
Development of athletic learning media for elementary school students
Authors: Da'i Mohamad , Apriyanto Rohmad , Ningsih Wahyu , Mellati Ita Khusnia
Published: January 2025

The problem that faced in athletic learning is the interesting and motivates of athletic learning media, for  students to learn has not been created, especially in the form of Android-based mobile learning. This research aims to develop the Smart Athletic App, and determine the feasibility of the product based on expert validation and usability factors. This type of research is Research and Development (R&D) which uses the ADDIE development model. The subjects of this research are 1 media expert, 1 material expert, and 22 class V students at SDN Sambiroto. The instrument used was aim to  measure product feasibility based on validation and usability factors. The results of this research obtained: (1) Creation of Athletic Smart Apps Products; (2) Feasibility has been well tested in terms of material, media, and usability factors in the "very feasible" category. Expert validation test results: (1) Material Expert of 4.47 is in the range > 4.0 as a result it is "very feasible" category; (2) The Media Expert Validation Score of 4.70 is in the range >4.0 thus dwtwemined "very feasible" category. The usability factor fromfeasibility test result of 6.24 is in the range > 5.5  "very feasible" category.
Character education facing the VUCA era through the PJBL model in penjas subjects
Authors: Suharti Suharti , Darmawan Agung Dwi , Harwanto Harwanto , Gunawan Wawan , Wiyarno Yoso
Published: January 2025

The aim of this research is to find out : (1) differences Character Education for PENJAS Subjects between the use of Project-Based Learning and conventional methods for Character Education for PENJAS Subjects, (2) differences High interest in learning and low interest in learning in the Character Education of PENJAS Subjects , and (3) the interaction between the learning model and Interest in learning in the Character Education of PENJAS Subjects , in this case Interest as a moderator variable really supports the strong relationship between the independent variable and the dependent variable . This experimental research was carried out using a 2x2 factorial design. The subjects in this research were class VIII students consisting of four classes with 110 group B students. The subjects that were the focus of the experiment were taken at random, namely group B. This research hypothesis was tested using the Analysis of Variant (Anova) statistical test. The calculation results show that: Based on the results of hypothesis testing and discussion, it can be concluded as follows: (1) There is a difference in the influence of using Project-Based Learning and conventional methods on Character Education in PENJAS Subjects , namely that students who use Project-Based Learning are better Subjects PENJAS than students who use conventional methods, (2) There is a difference in the influence of high interest in learning and low interest in learning on character education in PENJAS subjects , namely students with high interest in learning are better in PENJAS subjects than students with low interest in learning, and (3 ) There is an interaction effect between the learning model and interest in learning on the character education of the PENJAS subject , in this case interest as a moderator variable really supports the strong relationship between the independent variable and the dependent variable. The effect of using project-based learning with high interest can improve PENJAS subjects
Self-Confidence Through Canva Aplication, Wordwall and Ular Tangga in Solving Algebra Problems
Authors: Maryati Iyam , Yulianti Yanti
Published: January 2025

Self-confidence is a positive attitude that is the most important basic capital in a person to be able to develop his abilities to achieve whatever he wants and can do, both towards himself and the environment or situations he faces, including in learning. However, the Trends in International Mathematics and Science Study (TIMSS) data indicates that Indonesian students' self-confidence still needs to improve by at least 30%. This study assesses junior high school students' confidence in solving algebraic problems. This study employs a qualitative, descriptive research methodology. To analyse the data, conclusions were drawn, and the percentage of students who used the Canva app, Wordwall, and the Ular tangga game to gain confidence in their ability to solve algebraic problems was described. Thirty-six junior high school students in class VII served as the research subjects. Cognitive test sheets and observations were the study tools used. This study looked at four characteristics of self-confidence: 1) Act independently in making decisions; 2) Have a positive self-concept; and 3) Dare to voice thoughts. When choosing the learning models and media to employ in teaching and learning activities, teachers can benefit from the findings of this research. Thus, the Canva application and Wordwall media are able to increase self-confidence in class VII junior high school students.
The Role of Self-Efficacy in Enhance Metacognitive and Academic Performance Through Problem-Solving
Authors: Anggraini Elisa , Subanji Subanji , Rahardjo Swasono
Published: January 2025

This research analyzes the role of self-efficacy in enhancing metacognitive and academic performance of students through problem-solving as learning process. Researchers research some students from senior high school in Malang. This research uses mixed methods with surveys, interviews, and analysis of students’ learning outcomes. At the first meeting, students were asked to fill survey about the dimensions of self-efficacy, which are magnitude, strength, and generality. Moreover, researchers interviewed students to explore their metacognitive activities that they do, such as awareness, regulation, and evaluation. After that, researchers analyze their learning outcomes to determine their academic performance. This research result shows that students with a high dimension of self-efficacy tend to show better metacognitive activity than the other. Furthermore, students with a high dimension of self-efficacy tend to show better academic performance than others.
Induction of natural organogenesis in succulent species under different growth conditions
Authors: Carrillo-Landell Felipe Guadalupe , Diosdado-González María Guadalupe , Hernández-Barrera Alejandra , Alvarez-Medina Dora Alicia
Published: January 2025

Direct and indirect organogenesis depends largely on the type of explant, especially if they are juvenile and poorly differentiated explants, these will respond better to in situ or in vitro culture. The formation of shoots and adventitious buds is generally a challenge in tissue culture, resorting to creating stressful conditions or the use of plant hormones. However, if the above has been successful, the rooting phase can become complicated and it is necessary to use growth regulators. In this study, salt stress, nature of the substrate and relative humidity were evaluated as a whole as factors that intervene in the processes of shoot formation in succulent plants in the region, without making use of growth regulators with the aim of guaranteeing optimal conditions. that improve their reproduction for subsequent commercialization and/or conservation of the species.
Determination of total carbon stored in reforestations established in the National Park Iztaccíhuatl Popocatépetl
Authors: Carrillo-Anzures Fernando , Acosta-Mireles Miguel , Martínez-Ramírez Mayra , Flores-Ayala Eulogio
Published: January 2025

The Natural Protected Areas, are considered highly efficient, given their natural vocation and the objectives which are to keep their forests and meadows in perfect condition The objective of this work was to generate allometric equations to estimate biomass and carbon from Pinus hartwegii and Muhlenbergia macroura, in addition to the carbon content in the soil, considered as carbon reservoirs. A destructive sampling of 94 trees from one to ten years old and 55 grass samples was carried out. The study was conducted in the Iztaccíhuatl-Popocatépetl National Park. Carbon from aerial biomass in reforestation and natural grassland was calculated using the generated equations and data obtained from 234 sampling sites. For the organic carbon determination in the soil, 35 samples were extracted at two depths (0-15 and 15-30 cm). The resulting equation for the estimation of the Pinus hartwegii biomass was B=0.0092Db2.7303 and for Muhlenbergia macroura the equation were B=0.075+0.00001393Db2h. The average carbon content was 50.3 and 42.1% for trees and pastures, respectively. In order of magnitude the total carbon storage in the 750 hectares was 76,566.7 Mg of C in the soil, 2,249.50 Mg of C in pastures and 37.12 Mg of C in reforestation.
Effects of dimethyl sulfoxide intratesticular injection on structure of seminiferous tubule: A model for the study of testicular dopaminergic function in the rat
Authors: Morán-Perales José Luis , Martínez-Aguilar Pablo Isaac , Handal-Silva Anabella , García-Suástegui Wendy Argelia
Published: January 2025

We study the effects of an intratesticular injection (ITIn) of infiltrating agent dimethyl sulfoxide (DMSO) on seminiferous tubule structure in adult rats. Experimental groups of 32 rats received a ITIn with 50µL of pure DMSO inside each testicle; the sham group were formed with 32 rats subjected to surgical technique but not received ITIn; to test the DMSO effectiveness like infiltrating agent, other rats group received the ITIn with 50µg of haloperidol (dopaminergic antagonist) dissolved in DMSO. All the rats were sacrificed at 4-, 8-, 12- or 16-day post ITIn. Compared with sham groups, DMSO doesn’t alter the structure of seminiferous epithelium in no evaluated days, but the haloperidol ITIn showed progressive alterations on structure of seminiferous tubule from the 8th to the 16th day. Our results allow recommending the use of DMSO as an infiltrating agent in subsequent studies of dopaminergic testicular function.
Obsessive skincare and liver toxicity: a case report on titanium dioxide exposure
Authors: Kaya Fatih Öner , Abunawas Mohammad Jamal , Mert Pınar
Published: January 2025

ÖZET
Bu Vaka Raporu, topikal olarak kullanıldığında karaciğer
toksisitesinin bir sebebi olarak titanyum dioksitin (TiO2)
rolünü vurgulamaktadır. Avrupa Komisyonu, titanyum
dioksidin (E171) gıda katkısı olarak kullanılmasını
yasaklamasına rağmen, hala geniş çapta dermatolojik
ürünlerde kullanılmaktadır. Burada, bir hastanın kliniğimize
nöbet geçirdikten sonra başvurduğu ve hikayesinin
incelenmesi sonucu son bir aydır yaygın vücut ağrıları ve
deri döküntüleri yaşadığı ortaya çıktı. Tesadüfen karaciğer
enzimlerinin önemli ölçüde yüksek bulunan bu hastada
karın ultrasonografisinde hepatomegali ve karaciğer
yağlanması tespit edildi, bu da karaciğer biyopsisi ile
doğrulandı. Detaylı araştırma hastanın obsesif cilt bakım
alışkanlıklarının ortaya çıkmasına neden oldu, bu da
herhangi bir toksik maruziyeti tespit etmek için geniş
tarama testleri gerektirdi. Bu testlerin sonucunda anormal
olarak kan testlerinde yüksek miktarda titanyum bulundu.
TiO2 partikülleri tehlikeli özelliklerle ilişkilendirilmiştir ve
insan sağlığı hatta çevre için bile bir tehdit oluşturur;
dolayısıyla, çeşitli ürünlerdeki yaygın kullanımı olduğundan
bu toksik etkileri en aza indirmek için maruz kalma yollarını
araştıran daha fazla çalışmayı gerektirir.
Anahtar Kelimeler: Karaciğer toksisitesi, titanyum dioksit,
dermatolojik ürünlerin yan etkileri
New Late Cretaceous fruit and its seeds from the Ingersoll Shale (eastern Alabama, U.S.A.) indicate affinity with Ranunculaceae (Ranunculales)
Authors: Axsmith Brian J. , Stults Debra Z. , Wang Wei , Boucher Lisa D.
Published: January 2025

We describe a new ranunculacean fruit from Ingersoll Shale sediments (Santonian, 85.5 to 83.5 Ma), a part of the Eutaw Formation as it occurs in eastern Alabama. The Ranunculales/Ranunculaceae are basal eudicots but their fossil record is not well documented which is most likely due to their taxa being predominantly herbaceous and therefore lacking a propensity for fossilization. Two fruits are in evidence, one is a mature fruit in the process of dehiscence and in which several seeds are describable, and the other is interpreted as a less mature fruit. From these fruits, we describe a new genus, Costellifructus Axsmith, Stults, Wang, et Boucher gen. nov., and species, Costellifructus alabamensis Axsmith, Stults, Wang et Boucher sp. nov. Both fruits are urceolate and display follicles that are fused at the base and maintain this fusion through the length of the main body of the fruit thus forming a capsule. The fusion of follicles is denoted by areas of depression on the fruit. Especially observable in the large fruit are follicular ridges which continue into long stylar extensions. Interestingly, this is a character which is also very recognizable on extant ranunculacean genera such as Aquilegia L. and Delphinium Tourn. ex L. Seeds are characterized as small (2.5 × 2 mm), rugose, ridged, obovate longitudinally, and trigonal in cross-section profile, properties fitting within some ranunculacean taxa.
Fossil remains of the genus Crataegus (Rosaceae, Amygdaloideae) from south-eastern Armenia
Authors: Gabrielyan Ivan , Sargsyan Merine , Achoyan Arpine
Published: January 2025

As a result of the research, we determined the sectional affiliation of fossil remains of the genus Crataegus from the Early Pleistocene of the south-eastern part of Armenia, in the middle reaches of the Vorotan River. Plant fossils and imprints help to establish the distribution of species over the Earth’s surface during different geological periods. Of particular interest are the findings of species of the genus Crataegus, which is considered to be systematically very complex due to its inherent hybridization, apomixis, and polyploidy. In the modern flora of Armenia, the genus Crataegus is represented by three sections with 23 species. Comparative macromorphological analysis of fossil and modern hawthorns showed that the studied fossil remains belong to the section Crataegus. Among the species found in the territory, in terms of macromorphological characteristics, they are close to Crataegus rhipidophylla, C. caucasica and C. monogyna.
Tufted wind-dispersed fagalean fruits, Pogonokarydion gen. nov., from the Upper Eocene Florissant Formation of Colorado, USA
Authors: Manchester Steven R. , Judd Walter S.
Published: January 2025

Wind-dispersed comose fruits from the Late Eocene of Florissant, Colorado, USA, are recognized as a new genus of fagalean affinity. Pogonokarydion crassulum (Cockerell) gen. et comb. nov. disseminules consist of an ellipsoidal to circular nut bearing longitudinal ribs, a persistent epigynous perianth, paired styles, and a prominent tuft of straight hairs arising from the base, which we infer to be homologous with an involucre. Prior assignments to Juncus (Juncaceae) and Fagopsis (Fagaceae) are rejected and we argue for a position within the Fagales, likely within, or close to, the Betulaceae. Pogonokarydion co-occurred in the Florissant flora with other fagalean genera, including some still living today, like Quercus and Carya, and others now extinct like Fagopsis and Asterocarpinus.
Insight into the vegetation development of the Karkonosze Mountains (southwestern Poland) during the Late Vistulian and Holocene, based on data from glacial lakes
Authors: Wacnik Agnieszka , Madeyska Ewa
Published: January 2025

New palaeoecological records from two glacial lakes (the Mały Staw – 1183 m a.s.l. and the Wielki Staw – 1225 m a.s.l.) from the Polish Western Sudetes were obtained with the aim of better understanding the long-term vegetation development, the relationship between postglacial migration patterns, climate changes and human interference in mountainous areas, as well as to verify the local survival of some cold-adapted species during the Holocene maximum warming. Vegetation changes were reconstructed using pollen, spores and macrofossils. Several major stages of plant cover evolution over the last 12 000 years were identified. The end of the Late Vistulian (~12 100–11 700 cal BP) was documented for the first time in lake sediments from the region. During this period, the local vegetation was characterized by cold alpine meadows and patches of communities with shrubs (Betula nana, Alnus viridis, Salix, Juniperus, Ephedra) and trees growing at some distance from the lakes. In the Early Holocene, the expansion of boreal forests, consisting of Betula, Pinus sylvestris, as well as continental Larix and Pinus cembra, reached an altitude of ~1180 m a.s.l. An important discovery was the presence of Larix macrofossils in both studied profiles, which together with pollen evidence, confirmed its local persistence from the Early Holocene to the Middle Ages. It was also demonstrtaed that Betula nana, Selaginella selaginoides, Huperzia selago most probably persisted in the area from the Younger Dryas to at least the Middle Ages or even to the modern times, surviving through the Holocene climatic optimum. The increase in grassland representatives from ~4100 cal BP and the appearance of the cultivated plants (Triticum type pollen) from ~3300 cal BP, was due to the long-distance transport of pollen reflecting the development of agriculture and settlement outside the Karkonosze Mountains. It was not until the 10th century AD that the environment underwent a stronger anthropogenic transformation. Growing economic activities (e.g. metallurgy, mining of non-ferrous metal ores, glass production, forest industry) that developed, especially from the 12th century onwards required the supply of wood raw material. The development of agriculture in the region promoted the expansion of meadows and pastures and the greatest taxonomic diversity of herbaceous plants was recorded between the 13th and 15th centuries.
Remberella, a new genus of extinct ericalean flower from the Middle Miocene Latah flora of Washington and Idaho, USA
Authors: Manchester Steven R. , Judd Walter S.
Published: January 2025

Small pentamerous floral remains commonly encountered in Middle Miocene lake deposits of the Latah Formation of Washington and Idaho, USA, previously assigned to Diospyros, are here shown to represent an extinct genus. Newly recovered specimens preserve characters of the androecium and pollen that were previously unknown. Remberella microcalyx (Knowlton) gen. et comb. nov. flowers are actinomorphic, with five basally connate petals having an adnate androecium including ten staminodes and ten stamens. The elongate-triangular anthers contain finely rugulate, triaperturate pollen. The combination of pentamerous sympetalous corolla, ten staminodes in two whorls and ten stamens adnate to the corolla indicates affinity with early divergent superasterids, likely the Ericales, with intriguing similarities to Ebenaceae. Although the Miocene flora includes many genera confidently assigned to extant genera, Remberella adds to a growing number of contemporary extinct genera.
Less is better than more: reassessing the monotypic nature of Irpicodon (Amylocorticiaceae, Basidiomycota)
Authors: Palla Balázs , Dima Bálint , Papp Viktor
Published: January 2025

Within the family Amylocorticiaceae, conspicuous morphological affinities exist among the previously defined species Irpicodon pendulus, Plicaturopsis crispa and Plicatura nivea. With the aid of macro- and micro-morphological characters and phylogenetic evidence based on 3-gene datasets, a comprehensive reassessment of generic boundaries within these taxa was conducted. Upon reviewing the systematic position of the taxa included, the three genera emerged as a well-defined monophyletic clade. Based on the genetic divergence observed, coupled with the robust support for monophyly, similarities in ecological roles, and congruence in macro- and micromorphological characteristics, we suggest a revised genus concept that synonymizes Irpicodon (as well as Plicaturopsis) with the earliest established genus Plicatura.
Novel and uncommon bryophilous fungi from Brazil
Authors: Leão-Ferreira Sheila Miranda , Souza Maria Gabriella Andrade Primo de , Gusmão Luís Fernando Pascholati
Published: January 2025

Bryophilous fungi are an understudied group with unknown biodiversity in tropical regions, and are often underestimated worldwide. In Brazil, research on this ecological group has primarily focused on the southern and southeastern regions. During a survey of bryophilous fungi in the northeastern region, specifically in Bahia State, two novel species, Brachydesmiella bahiensis and Dendryphiosphaera longispora, were discovered. Brachydesmiella bahiensis resembles B. biseptata and B. caudata, but exhibits conidial distal cell morphology between these two species. Dendryphiosphaera longispora has longer conidia than other species within the genus. Also, the uncommon microfungus Dwibeeja sundara was reported for the second time globally. Detailed descriptions and illustrations of each species are provided.
LITERATURE REVIEW OF CONCEPT ATTAINMENT MODEL TECHNOLOGY: THE EFFECTIVENESS CONCEPT ATTAINMENT MODEL MIXED WITH OTHER MODEL IN COMPUTATION WORK
Authors: Rizal Sofian , Wibawa Basuki , Arifin Ifik Lakswirinto , Hanafi Ivan , Susanto Teguh Trianung Djoko
Published: January 2025

Concept attainment is an instructional strategy that uses a structured inquiry process. Students fail to grasp the certain concepts of subject, which lead disinterest among students. Moreover students are often unable to apply their knowledge to advance studies. In concept attainment, students figure out the attributes of a group or category that has been provided by the teacher. The purpose of this study is to determine the effect of applying the concept attainment model mix with other model on students critical thinking skill and the use of technology in teaching. The literature review method was used to collect and analyze the relevant literature in this field. The results of this literature review reveal that the concept attainment model mix with other model have proven effective in enhancing students understanding and practical skills and found there will be significant difference between the mean achievement scores of the science or social students taught. The strategy is based on the research investigated how different variables affected the concept learning process and the use of technology in teaching have proven effective in enhancing students understanding and practical skills. However, several challenges were also identified, such as the lack of adequate resources and facilities, the need for increased training of lecturers, and adaptation to technological changes in the concept attainment model. Further research is needed to address this challenge and develop the concept attainment model that are more integrated and relevant to industry needs. By taking into account the findings of this literature review, it is hoped that the concept attainment model mix with other model on students critical thinking skill and the use of technology in teaching can be improved, so that students can acquire the knowledge and skills needed to be successful in the world of computaion work.
TOURISM TRANSFORMATION: ADDRESSING LEGAL GAPS IN MALAYSIA’S TOURISM INDUSTRY ACT 1992
Authors: Abu Bakar Marina , Ismail Sukriah , Azizan Muhammad Hafiz
Published: January 2025

The tourism industry is an important economic sector in Malaysia, contributing to economic development, job creation, and cultural promotion. The Tourism Industry Act 1992 (Act 482) plays a significant role in regulating and promoting the development of the tourism industry in Malaysia. However, since its enactment, there have been several weaknesses in this law that require attention and improvement. This study aims to analyse the legal interpretations within the Tourism Industry Act 1992 (Act 482), identify existing weaknesses, and propose practical solutions within the context of Malaysia. This study adopts a qualitative research design. The data for the study involves sources such as legal documents, industry reports, and existing tourism regulations in Malaysia. The analysis results show several key weaknesses in the act, including bureaucracy in the licensing process, non-comprehensive definitions, and disproportionate penalties. To address these weaknesses, this study proposes several solutions, such as improving the licensing process, updating legal definitions, and introducing better review and appeal mechanisms. This study emphasizes the importance of learning from best practices in developed countries to enhance the effectiveness and fairness in the implementation of tourism laws. With the proposed improvements, it is hoped that Malaysia’s tourism industry can continue to grow sustainably and competitively.
Parenting Lessons from Bringing Up Bébé: A Comparative Analysis with Islamic Education for Character Building
Authors: Zahro Latifatuz , Sutiah Sutiah
Published: January 2025

This study examines the parenting principles from Pamela Druckerman’s Bringing Up Bébé within the framework of Islamic education, with a focus on character building in early childhood. By employing a qualitative and descriptive-analytic approach, the research compares key parenting practices such as discipline, self-control, independence, and communication, highlighting their alignment with Islamic values. The findings demonstrate significant parallels between French parenting techniques and Islamic teachings, particularly in fostering discipline and respect. By integrating these principles into Indonesian parenting practices, the study offers actionable insights for addressing contemporary parenting challenges while preserving Islamic values. This research underscores the universality of effective parenting methods and recommends further exploration of their applicability across diverse cultural and religious contexts.
Balancing Challenges and Opportunities: Enhancing Early Childhood Cognitive Skills Through Digital Tools
Authors: Loka Novita , Sabila Rizky Thania
Published: January 2025

This study investigates the role of digital tools, particularly educational videos, in enhancing early childhood cognitive skills at Pertiwi Indralaya Kindergarten. Using a qualitative descriptive approach based on the Miles and Huberman framework, data were collected through classroom observations, interviews, and documentation involving 20 children aged 4–5. Findings reveal that 55% of students exhibited "Very Well Developed" cognitive skills, while 45% were "Developing as Expected," with no children in lower categories. Key cognitive areas improved included problem-solving, memory retention, and logical reasoning, supported by a balanced integration of digital and traditional learning methods. Challenges such as maintaining focus and avoiding screen dependency underscore the need for structured guidance. The study concludes that combining digital and conventional strategies can foster cognitive development, highlighting the importance of teacher facilitation and responsible technology use in early childhood education.
Trainees’ beliefs about the use of cinema as a tool for EFL
Authors: Sánchez-Auñón Estefanía , Férez Mora Pedro Antonio , Monroy Hernández Fuensanta
Published: January 2025

Despite the growing presence of cinema in the classroom and the multiple benefits it has been proved to have for the teaching of English as a foreign language (EFL), the implementation of films in the English lessons is still an under-researched area, particularly, as regards instructors’ views on the adequacy of this material. Thus, the present study delves into trainees’ beliefs (N = 121) regarding the potential of cinema for EFL before and after analysing a film-based lesson plan. Questionnaires, open-ended questions, and focus groups were employed to obtain quantitative and qualitative data on the perceived linguistic, intercultural, and motivational advantages of films. The results reveal that, at the outset of the research, trainees held cinema especially useful for eliciting linguistic and intercultural knowledge. However, they were unaware of how to exploit this textual modality and considered some of its characteristics problematic for class use. In the post-analysis stage, the participants assigned similar rates of importance to the three analysed dimensions, reflecting an even more favourable attitude towards this resource. This positive change trend seems to stem from a broadened awareness of the proper exploitation of film after examining the lesson plan provided. Pedagogical and research implications are also defined.
Examining two form-focused instruction combinations and their relationship with language-analytic ability in young learners: A study on the English possessive determiners his/her
Authors: Martínez-Adrián María , Iglesias-Diéguez Kevin
Published: January 2025

Recent work conducted in input-limited classrooms with young learners has made a call for the incorporation of form-focused instruction (FFI) in the form of focused tasks and/or additional treatments that could help learners expand their attention to grammar. Current research has also uncovered the need for the examination of the interaction between FFI, individual differences, such as language-analytic ability, and language achievement. Thus, this paper examines the effect of two forms of FFI (dictogloss+self-correction and dictogloss+metalinguistic explanations [ME]) on learners’ accuracy in the use of the possessive determiners his/her in the final product of the dictogloss tasks performed. It also looks into the interface between FFI and languageanalytic ability as measured by the MLAT-ES for child language. To do so, 33 Basque/ Spanish bilingual learners of English (aged 10-11) were split into a dictogloss+selfcorrection and a dictogloss+ME group. Participants were asked to complete three collaborative dictogloss tasks targeting the possessive determiners his/her in three consecutive weeks. The dictogloss+ME group achieved greater accuracy in the use of the possessive determiners his/her than the group with self-correction. Likewise, the benefits observed in the former were independent of participants’ language-analytic ability, all of which suggests a blurring effect of the ME treatment received.