bluuebunny/crossref_metadata_2025 huggingface dataset:
The impact of residential greenness on psychological distress among Hurricane Katrina survivors
Authors: Burrows Kate , Fong Kelvin C. , Lowe Sarah R. , Fussell Elizabeth , Bell Michelle L.
Published: May 2023

Residential greenness may support mental health among disaster-affected populations; however, changes in residential greenness may disrupt survivors’ sense of place. We obtained one pre- and three post-disaster psychological distress scores (Kessler [K]-6) from a cohort (n = 229) of low-income mothers who survived Hurricane Katrina in New Orleans, Louisiana, USA. Greenness was assessed using average growing season Normalized Difference Vegetation Index (NDVI) and Enhanced Vegetation Index (EVI) in the 300 m around participants’ homes at each time point. We used multivariable logistic regressions to evaluate two hypotheses: 1) that cross-sectional greenness (above vs. below median) was associated with reduced psychological distress (K6≥5); and 2) that changes in residential greenness were associated with adverse mental health. When using EVI, we found that a change in level of greenness (i.e., from high to low [high-low], or from low to high [low-high] greenness, comparing pre- and post-Katrina neighborhoods) was associated with increased odds of distress at the first post-storm survey, compared to moving between or staying within low greenness neighborhoods (low-high odds ratio [OR] = 3.48; 95% confidence interval [CI] = 1.40, 8.62 and high-low OR = 2.60; 95% CI: 1.05, 6.42). Results for NDVI were not statistically significant. More research is needed to characterize how residential greenness may impact the health of disaster survivors, and how these associations may change over time.
What matters for international consumers’ choice preferences for smartphones: Evidence from a cross-border ecommerce platform
Authors: N’da Karamoko , Ge Jiaoju , Ji-Fan Ren Steven , Wang Jia
Published: May 2023

Despite the growing impact of smartphone use on countries’ economies, the literature has rarely investigated the link between economic context and smartphone purchase trends. Based on 20,556 smartphones sold from a Cross-Border E-Commerce (CBEC) platform, the study reveals that relationships between GDP per capita and Smartphone Choice Preferences (SCP) as well as Purchase Quantities (PUR) are direct and partially mediated by Price (PRI), Read-Only Memory (ROM), and Random-Access Memory (RAM). That means that the economic context highlighted by the GDP plays a substantial role in smartphone choices and purchases. The study suggests that e-sellers and smartphone brands should adapt their marketing and manufacturing strategies to the countries’ economic contexts to leverage the fearless competition in the smartphone industry.
The stigma associated with cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL): A protocol for a systematic review
Authors: Nuwangi Hasara , Agampodi Thilini Chanchala , Price Helen Philippa , Shepherd Thomas , Weerakoon Kosala Gayan , Agampodi Suneth Buddhika
Published: May 2023

Leishmaniasis is a neglected tropical disease with three main clinical types; cutaneous leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), and visceral leishmaniasis (VL). CL and MCL are considered to be highly stigmatizing due to potentially disfiguring skin pathology. CL and MCL-associated stigma are reported across the world in different contexts assimilating different definitions and interpretations. Stigma affects people with CL, particularly in terms of quality of life, accessibility to treatment, and psycho-social well-being. However, evidence on CL- and MCL-associated stigma is dispersed and yet to be synthesized. This systematic review describes the types, measurements, and implications of the stigma associated with CL and MCL and identifies any preventive strategies/interventions adopted to address the condition. This study was developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) statement which is registered in the International Platform of Registered Systematic Review and Meta-analysis Protocols PROSPERO (ID- CRD42021274925). We will perform an electronic search in MEDLINE, Embase, Scopus, PubMed, EBSCO, Web of Science, Global Index Medicus, Trip, and Cochrane Library databases, and in Google Scholar, using a customized search string. Any article that discusses any type of CL- and/or MCL-associated stigma in English, Spanish and Portuguese will be included. Articles targeting veterinary studies, sandfly vector studies, laboratory-based research and trials, articles focusing only on visceral leishmaniasis, and articles on diagnostic or treatment methods for CL and MCL will be excluded. Screening for titles and abstracts and full articles and data extraction will be conducted by two investigators. The risk of bias will be assessed through specific tools for different study types. A narrative synthesis of evidence will then follow. This review will identify the knowledge gap in CL-associated stigma and will help plan future interventions.
Possible role of caffeine in nicotine use onset among early adolescents: Evidence from the Young Mountaineer Health Study Cohort
Authors: Kristjansson Alfgeir L. , Kogan Steven M. , Mann Michael J. , Smith Megan L. , Lilly Christa L. , James Jack E.
Published: May 2023

Background

Preventing nicotine use onset among children and youth is an important public health goal. One possible contributor that has received little empirical investigation is caffeine use. The goal of this study was to examine the possible contribution of caffeine to nicotine onset during early adolescence.

Methods

We used data from the Young Mountaineer Health Study Cohort. Survey data were collected from 1,349 (response rate: 80.7%) 6th grade students (mean age at baseline 11.5 years) in 20 middle schools in West Virginia during the fall of 2020 and spring of 2021. We limited our analyses to students reporting never having used any form of nicotine at baseline. Logistic regression was employed in analyses.

Results

Approximately 8% of participants reported having used nicotine at least once between baseline and the follow-up, and 4.7% reported solely using electronic nicotine delivery systems (ENDS) and no other forms of nicotine. In multivariable analyses, we controlled for many environmental, social, and behavioral variables known to influence nicotine use such as alcohol use, peer substance use, and perceived access to nicotine. We formulated our main independent variable, caffeine consumption, as continuous deciles. Any nicotine use, as well as ENDS use only at follow-up, were modeled as dependent variables. Caffeine was significantly associated with nicotine use in both models with ORs of 1.15 (1.04–1.27) and 1.13 (1.00–1.28).

Conclusions

Caffeine consumption among 6th grade non-nicotine users was associated with nicotine use at approximately 6-months follow-up.
α-Hemolysin promotes uropathogenic E. coli persistence in bladder epithelial cells via abrogating bacteria-harboring lysosome acidification
Authors: Naskar Manisha , Parekh Viraj P. , Abraham Mathew A. , Alibasic Zehra , Kim Min Jung , Suk Gyeongseo , Noh Joo Hwan , Ko Kwan Young , Lee Joonha , Kim Chungho , Yoon Hana , Abraham Soman N. , Choi Hae Woong
Published: May 2023

There is a growing consensus that a significant proportion of recurrent urinary tract infections are linked to the persistence of uropathogens within the urinary tract and their re-emergence upon the conclusion of antibiotic treatment. Studies in mice and human have revealed that uropathogenic Escherichia coli (UPEC) can persist in bladder epithelial cells (BECs) even after the apparent resolution of the infection. Here, we found that, following the entry of UPEC into RAB27b+ fusiform vesicles in BECs, some bacteria escaped into the cytoplasmic compartment via a mechanism involving hemolysin A (HlyA). However, these UPEC were immediately recaptured within LC3A/B+ autophagosomes that matured into LAMP1+ autolysosomes. Thereafter, HlyA+ UPEC-containing lysosomes failed to acidify, which is an essential step for bacterial elimination. This lack of acidification was related to the inability of bacteria-harboring compartments to recruit V-ATPase proton pumps, which was attributed to the defragmentation of cytosolic microtubules by HlyA. The persistence of UPEC within LAMP1+ compartments in BECs appears to be directly linked to HlyA. Thus, through intravesicular instillation of microtubule stabilizer, this host defense response can be co-opted to reduce intracellular bacterial burden following UTIs in the bladder potentially preventing recurrence.
Global commercialization and research of veterinary vaccines against Pasteurella multocida: 2015–2022 technological surveillance
Authors: Domínguez-Odio Aníbal , Delgado Daniel Leonardo Cala
Published: May 2023

Background and Aim: Pasteurella multocida can infect a multitude of wild and domesticated animals, bacterial vaccines have become a crucial tool in combating antimicrobial resistance (AMR) in animal production. The study aimed to evaluate the current status and scientific trends related to veterinary vaccines against Pasteurella multocida during the 2015–2022 period.

Materials and Methods: The characteristics of globally marketed vaccines were investigated based on the official websites of 22 pharmaceutical companies. VOSviewer® 1.6.18 was used to visualize networks of coauthorship and cooccurrence of keywords from papers published in English and available in Scopus.

Results: Current commercial vaccines are mostly inactivated (81.7%), adjuvanted in aluminum hydroxide (57.8%), and designed to immunize cattle (33.0%). Investigational vaccines prioritize the inclusion of attenuated strains, peptide fragments, recombinant proteins, DNA as antigens, aluminum compounds as adjuvants and poultry as the target species.

Conclusion: Despite advances in genetic engineering and biotechnology, there will be no changes in the commercial dominance of inactivated and aluminum hydroxide-adjuvanted vaccines in the short term (3–5 years). The future prospects for bacterial vaccines in animal production are promising, with advancements in vaccine formulation and genetic engineering, they have the potential to improve the sustainability of the industry. It is necessary to continue with the studies to improve the efficacy of the vaccines and their availability.

Keywords: adjuvant, Pasteurella multocida, strain, technological surveillance, vaccine.
Fructose‐induced salt‐sensitive blood pressure differentially affects sympathetically mediated aortic stiffness in male and female Sprague‐Dawley rats
Authors: Komnenov Dragana , Rossi Noreen F.
Published: May 2023

Hypertension is the leading risk factor for major adverse cardiovascular events (MACE). Aortic stiffness and sympathoexcitation are robust predictors of MACE. Combined high fructose and sodium intake increases arterial pressure, aortic stiffness, renin, and sympathetic nerve activity in male rats. We hypothesized that activation of the renin angiotensin system (RAS) and/or the sympathetic system mediates aortic stiffness in rats with fructose‐induced salt‐sensitive blood pressure. Male and female Sprague‐Dawley rats ingested 20% fructose or 20% glucose in drinking water with 0.4% NaCl chow for 1 week. Then, fructose‐fed rats were switched to 4% NaCl chow (Fru + HS); glucose‐fed rats remained on 0.4% NaCl chow (Glu + NS, controls for caloric intake). After 2 weeks, mean arterial pressure (MAP) and aortic pulsed wave velocity (PWV) were evaluated at baseline or after acute intravenous vehicle, clonidine, enalapril, losartan, or hydrochlorothiazide. Baseline global longitudinal strain (GLS) was also assessed. MAP and PWV were greater in male Fru + HS versus Glu + NS male rats (p < 0.05 andp < 0.001, respectively). PWV was similar between the female groups. Despite similarly reduced MAP after clonidine, PWV decreased in Fru + HS versus Glu + NS male rats (p < 0.01). Clonidine induced similar decreases in MAP and PWV in females on either diet. GLS was lower in Fru + HS versus Glu + NS male rats and either of the female groups. Thus, acute sympathoinhibition improved aortic compliance in male rats with fructose salt‐sensitive blood pressure. Female rats retained aortic compliance regardless of diet. Acute RAS inhibition exerted no significant effects. Male rats on fructose high salt diet displayed an early deficit in myocardial function. Taken together, these findings suggest that adult female rats are protected from the impact of fructose and high salt diet on blood pressure, aortic stiffness, and early left ventricular dysfunction compared with male rats.
Soldaten vor der Tür – die jüdische Gemeinde in Fürth im Spannungsverhältnis zwischen Militär und Obrigkeit
Authors: Strobel Franziska
Published: May 2023

Quartering soldiers in private houses was still very prone to conflict in the 18th century. In the following article, I focus on this practice using the example of quartering during the Seven Years’ War in the households of the inhabitants of Fürth, a market town near Nuremberg. Particular attention is primarily on the reaction and the opportunities for maneuver of the Jewish community and their efforts to free themselves from the quarterings between them and the Christian community and the Jewish community, respectively, as well as the divided local authorities. This conflict shows the way in which the religious and authoritarian boundaries functioned, and the extent they gave the individual actors room for action or limited it. A praxeological, actor-centered approach is employed to generate new insights into the conditions and manifestations of Jewish life.
Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome
Authors: Zhai Jiajia , Li Zeping , Zhang Huifeng , Lu Zuowei , Zhang Yi , Li Mo , Kang Jian , Yang Zelong , Ma Louyan , Ma Li , Ma Zhengquan , Ma Xiaorui , Zhao Fanghong , Ma Xiaoqing , Gao Yuan , Zhang Yuanyuan , Li Xiaomiao
Published: May 2023

Diabetic nephropathy is a microvascular complication of diabetes mellitus, threatening the health of millions of people. Herein, we explored a blood glucose independent function of coptisine on diabetic nephropathy. A diabetic rat model was established by intraperitoneal administration of streptozotocin (65 mg/kg). Coptisine treatment (50 mg/kg/day) retarded body weight loss and reduced blood glucose. On the other hand, coptisine treatment also decreased kidney weight and the levels of urinary albumin, serum creatinine, and blood urea nitrogen, indicating an improvement of renal function. Treatment with coptisine also mitigated renal fibrosis, with alleviative collagen deposition. Likewise, in vitro study showed that coptisine treatment decreased apoptosis and fibrosis markers in HK-2 cells treated with high glucose. Furthermore, after coptisine treatment, the activation of NOD-like receptor pyrin domain containing protein 3 (NRLP3) inflammasome was repressed, with decreased levels of NLRP3, cleaved caspase-1, interleukin (IL)-1β, and IL-18, indicating that the repression of NRLP3 inflammasome contributed to the effect of coptisine on diabetic nephropathy. In conclusion, this study revealed that coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome. It is indicated that coptisine may have the potential to be used in the diabetic nephropathy treatment.
Pre-objective reality and the end of the world
Authors: Baker Baranna
Published: May 2023

In Hard-Boiled Wonderland and The End of the World, Haruki Murakami plays with the quantum idea of the Many Worlds theory, creating two universes that exist in a state of parallelism – one consisting of the main character’s objective/subjective reality, the other being a pre-objective reality that resides within the character’s inaccessible subconscious mind. These universes are linked within the purely objective, surreal world of the novel by a series of indexical signs and symbols that point the reader back and forth between the worlds, indicating that they are linked by certain shared subjectivities. What follows here is an exploration of how Murakami’s novel works from a semiotic point of view.
An Alternative Approach to Frequency of Patent Technology Codes: The Case of Renewable Energy Generation
Authors: Terrazas-Santamaria Diana , Mendoza-Palacios Saul , Berasaluce-Iza Julen
Published: May 2023

This article proposes a methodology to identify technological transitions (TTs) by systematically using the total variation distance (TVD) metric. We use a database of renewable energy generation (REG) patents to exemplify the usefulness of TVD to uncover moments where a “big change” in REG technology happened. To do this, we compare the observed frequency distribution of technology codes of REG patents filed between 1973 and 2015 in the US, spread across seven categories (e.g., wind and tidal). We identify two crucial TTs, one at the beginning of the 1980s and another in the late 1990s and early 2000s. In this manner, we reconcile qualitative evidence that registers major REG changes with a quantitative measure that reflects them. Policy evaluations or causality analyses often rely on identifying TTs accurately; therefore, this approach is not constrained to the REG technology or TTs but helps reveal such transition moments in a database whose characteristics are suitable for the use of TVD.
Family language policy in Swedish-English families: Rhizomatic conceptualisations
Authors: Roberts Tim
Published: May 2023

Although past research has established that family language policies are composed of numerous complex, entangled, heterogenous elements, as of yet, most works grounded within this research paradigm do not attempt to fully embrace this complexity. This article argues that the complexity can be more fully engaged with by conceptualising a family language policy as a rhizomatic system which consists of a multiplicity of temporary assemblages. Drawing on video recordings, interviews, and stimulated recall protocols from a project on the dimensions of language in Swedish-English families, this article aims to consider how interactional episodes within these families can be viewed as an assemblage of material elements, experiences, agential forces, and conceptual discourses. It is argued that through the analysis of multiple assemblages, and through the consideration of the connectivity between such assemblages, that a holistic picture of the rhizomatic structure that is a family language policy begins to be built.
Language contact between Italian and English: a case study on nouns ending in the suffix -ing
Authors: Meinschaefer Judith
Published: May 2023

The article deals with how English deverbal nouns with the suffix -ing have been imported into Italian. The focus is on the semantic characteristics of these borrowed nouns in Italian and, in particular, on the question of whether they have been borrowed not as simple sign-concept pairings but with argument and event structure. In previous research, it has been claimed that argument and event structure need to be licensed by some overt functional element. Hence, borrowed deverbal nouns should have argument structure and event structure only if they have an overt affix, in other words, only if the forms are not borrowed holistically as unsegmented words but retain internal morphological structure, implying that morphological borrowing of the affix has occurred. When a foreign affix combines with native bases of the recipient language, this is often considered an important criterion for morphological borrowing, which is clearly not the case for the suffix -ing in Italian. Here, it will be shown that contrary to expectation, numerous occurrences with argument and event structure may be found in a large Italian web corpus for a sample of English deverbal nouns ending in -ing, borrowed into (certain registers) of Italian.
Tailored thermal emission in bulk calcite through optic axis reorientation
Authors: Diaz-Granados Katja , Ma Weiliang , Lu Guanyu , Matson Joseph , Li Peining , Caldwell Joshua D.
Published: May 2023

The polar nature of calcite results in lattice vibrations that can be stimulated through gratings and nanostructures to design spatially and spectrally coherent thermal radiation patterns. In order to obtain optimal design control over such patterned materials, it is first necessary to understand the fundamental emissivity properties of the lattice vibrations themselves. Because calcite is a uniaxial material, when the optic axis (OA) is tilted with respect to the crystal surface, the surface wave solutions to Maxwell’s equations and vibrational modes that are permitted will change due to the crystal’s structural anisotropy. This implies that the OA orientation can play a critical role in dictating which modes can be harnessed when designing a narrowband or angular thermal emitter. Here we explore the angle and polarization dependence of the bulk far-field emissivity of unpatterned calcite with tilted OA. We show that by manipulating the OA orientation via crystallographic off-cut, polarization, and sample rotation, the emissivity at a given frequency can vary by as much as 0.8. These results suggest that, in addition to serving as a basis for modifying the behavior of the relevant phonon polaritons, OA orientation can be used to alter the thermal emission pattern without the need for complex lithographic patterning.
Essential oils of the ginger plants Meistera caudata and Conamomum vietnamense: chemical compositions, antimicrobial, and mosquito larvicidal activities
Authors: Huong Le Thi , The Son Ninh , Sam Ly Ngoc , Minh Phan Nhat , Luyen Nguyen Dinh , Hung Nguyen Huy , Dai Do Ngoc
Published: May 2023

The current study describes the chemical identification, antimicrobial, and mosquito larvicidal activities of essential oils from Meistera caudata and Conamomum vietnamense, growing in Vietnam. Essential oils were extracted from the leaves and rhizomes, and characterized by the GC-FID/MS (gas chromatography-flame ionization detection/mass spectrometry) analysis. Monoterpenes (33.1–89.2 %) were the main chemical class found in these oils. β-Pinene (30.8 %) and α-pinene (23.8 %) were two major compounds in M. caudata leaf oil. C. vietnamense leaf and rhizome essential oils were dominated by 1,8-cineole (47.9–62.0 %) and limonene (10.3–16.2 %). With the same MIC (minimum inhibitory concentration) value of 25 μg/mL, C. vietnamense leaf and rhizome essential oils strongly inhibited the growth of Gram-positive bacteria Staphylococcus aureus ATCC 29213 and Bacillus subtilis ATCC 6501, respectively. For 24 and 48-h treatments, C. vietnamense leaf essential oil strongly controlled the growth of mosquito Aedes aegypti with the respective LC50 values of 7.67 and 6.73 μg/mL, and the respective LC90 values of 13.37 and 10.83 μg/mL. In the same manner, C. vietnamense rhizome essential oil also showed strong mosquito larvicidal activity against Aedes albopictus with the LC50 values of 12.37 and 12.00 μg/mL, and the LC90 values of 20.56 and 18.58 μg/mL, respectively. C. vietnamense essential essential oils containing a high amount of 1,8-cineole are generally better than M. caudata essential essential oils in both two biological assays.
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
Authors: Nguyen‐Dien Giang Thanh , Kozul Keri‐Lyn , Cui Yi , Townsend Brendan , Kulkarni Prajakta Gosavi , Ooi Soo Siang , Marzio Antonio , Carrodus Nissa , Zuryn Steven , Pagano Michele , Parton Robert G , Lazarou Michael , Millard S Sean , Taylor Robert W , Collins Brett M , Jones Mathew JK , Pagan Julia K
Published: May 2023

To maintain both mitochondrial quality and quantity, cells selectively remove damaged or excessive mitochondria through mitophagy, which is a specialised form of autophagy. Mitophagy is induced in response to diverse conditions, including hypoxia, cellular differentiation and mitochondrial damage. However, the mechanisms that govern the removal of specific dysfunctional mitochondria under steady‐state conditions to fine‐tune mitochondrial content are not well understood. Here, we report that SCFFBXL4, an SKP1/CUL1/F‐box protein ubiquitin ligase complex, localises to the mitochondrial outer membrane in unstressed cells and mediates the constitutive ubiquitylation and degradation of the mitophagy receptors NIX and BNIP3 to suppress basal levels of mitophagy. We demonstrate that the pathogenic variants of FBXL4 that cause encephalopathic mtDNA depletion syndrome (MTDPS13) do not efficiently interact with the core SCF ubiquitin ligase machinery or mediate the degradation of NIX and BNIP3. Thus, we reveal a molecular mechanism whereby FBXL4 actively suppresses mitophagy by preventing NIX and BNIP3 accumulation. We propose that the dysregulation of NIX and BNIP3 turnover causes excessive basal mitophagy in FBXL4‐associated mtDNA depletion syndrome.
Something new under the sun: caspases promote cell survival under moderate heat stress
Authors: Suthar Komal Panchal , Bergmann Andreas
Published: May 2023

Since the discovery of caspases in 1993 (Yuan et al, 1993), they have largely been regarded as essential Cys proteases in apoptosis. However, more recently, it has become evident that caspases also have non‐apoptotic functions in the so‐called caspase‐dependent non‐lethal processes (CDPs) including cell proliferation and cell differentiation (Aram et al, 2017). While most of the non‐apoptotic functions were characterized under normal developmental conditions, a new study by Galasso et al took this examination a step further—to the analysis of moderate stress conditions. The authors now report that caspases have a non‐apoptotic prosurvival function in Drosophila ovarian somatic cells exposed to moderate heat stress by controlling Hedgehog signaling and autophagy (Galasso et al, 2023).
The KELAYAKAN SERAT LIDAH MERTUA (SANSEVIERIA TRIFASCIATA) SEBAGAIBAHAN PEMBUATAN BULU MATA PALSU UNTUK RIAS WAJAH SEHARI-HARI
Authors: Fatchuroh Alv
Published: May 2023

Abstrack. The tongue-in-law thrives in every yard, garden, and roadside. However the existence of an abundant tongue-in-law is underutilized by the society, especially in the field of beauty. Tongue-in-law (Sansevieria) has long and smooth leaf fibers, almost similiar with human hair. Therefore, the tongue-in-law fibers are processed into false eyelashes to support the results of daily makeup. The purpose of this study wre to find out the validity of falseeyelashes that made by tongue-in-law fibers and to determine the advisability of false eyelashes made by tongue-in-law fibers for daily makeup in terms of sensory and preference test. The method of this research used experimental method. The object of the study were 5 models of false eyelashes from tongue-in-law fibers, namely BM1, BM2, BM3, BM4, and BM5. This research took place in September 2019 â€“ March 2020. The results of the study based on the analysis of sensory test data showed that all product were considered very suitable with an average percentage of 86.25%. while the results of the favorite test showed that all products were very fond category with an average percentage of 85%.
Kelayakan Limbah Sekam Padi (Orysa Sativa L.) sebagai Bahan Tambahan Sediaan Sabun Mandi Padat Alami
Authors: Budiarti Zeni Tri , Agustin Eni Widhia
Published: May 2023

Sabun merupakan salah satu kosmetika pembersih yang bermanfaat untuk membersihkan kulit dari kotoran, debu dan sebum yang menempel di kulit. Penambahan sekam padi (oryza sativa .L) dalam sabun diharapkan dapat membuka pori pori dan mengangkat sel kulit mati sehingga meningkatkan daya pembersih karena sekam padi memiliki kandungan zat karbon. Tujuan dari penelitian ini adalah untuk mengetahui kelayakan sabun mandi dari sekam padi, untuk mengetahui kelayakan sabun mandi sekam padi dilakukan uji laboratorium, kemudian dilakukan uji inderawi, uji kesukaan dan uji klinis. Metode yang digunakan dalam penelitian ini adalah R&D (Research and Development). Metode pengumpulan data menggunakan observasi, dokumentasi, dan angket sedangkan teknik analisis data menggunakan deskriptif presentase. Uji laboratorium dilakukan di BPMSB Surakarta untuk mengetahui nilai pH, kadar asam lemak, kadar alkali bebas dan kadar air dengan hasil nillai pH pada formulasi 1 sebesar 10,38, formulasi 2 sebesar 9,75, dan formulasi 3 sebesar 10,29, sedangkan hasil uji kadar air pada formulasi 1 sebesar 13,43%, formulasi 2 sebesar 12,52% dan formulasi 3 sebesar 12,79%., untuk hasil uji asam lemak bebas pada formulasi 1 sebesar 0,28% dan formulasi 2 sebesar 0,31% dan hasil uji alkali bebas pada formulasi 3 sebesar 0,016% sehingga sabun mandi sekam padi dinyatakan lulus semua uji laboratorium SNI. Uji inderawi mendapatkan hasil 90% dengan kriteria sangat valid, uji kesukaan mendapatkan hasil 92% dengan kriteria sangat suka dan uji klinis sensitivitas tangan mendapatkan nilai akhir sebesar 100% dengan kriteria tidak menimbulkan reaksi atau alergi. Kesimpulan dari penelitian ini adalah produk sabun mandi padat alami dengan penambahan sekam padi (oryza sativa L.) bedasarkan hasil uji inderawi produk dinyatakan sangat layak, hasil uji kesukaan dinyatakan sangat suka dan hasil uji klinis dinyatakan tidak menimbulkan reaksi.
NILAI ESTETIKA TAS WANITA MOTIF BATIK DENGAN PEMANFAATAN LIMBAH SERABUT KELAPA DAN KOMBINASI KULIT SAPI
Authors: Ratnaningsih Griyanti Angga , Wahyuningsih Sri endah
Published: May 2023

Penelitian ini bertujuan untuk mengetahui estetika tas motif batik berbahan dasar kulit sapi dan limbah serabut kelapa. Pada tas wanita yang dinilai berdasarkan 2 aspek yaitu prinsip desain dan teori unsur. Adapun peneliti ini melakukan penelitian di kota Kebumen, Jawa Tengah. Penelitian yang digunakan adalah pre-eksperimental menggunakan penelitian deskriptif dengan pendekatan kualitatif. Metode yang digunakan dalam penelitian ini adalah metode wawancara, yang dilakukan dua belah pihak yaitu pewawancara (interviewer) yang mengajukan pertanyaan dan terwawancara (interview). Peneliti melakukan wawancara terhadap 9 orang dalam 3 bidang ahli yaitu pengrajin, penjual dan kolektor  tas. Hasil penelitian mengenai penilaian estetika tas wanita motif batik berbahan dasar kulit sapi dan limbah serabut kelapa menyatakan jika tas wanita motif batik dengan pemanfaatan limbah serabut kelapa dan kombinasi kulit sapi telah memenuhi nilai estetika berdasarkan teori prinsip desain yaitu irama, proporsi, keseimbangan, ukuran dan pusat perhatian serta unsur desain meliputi warna, bentuk ukuran dan testur. Dengan demikian dapat disimpulkan hasil penelitian ini bahwa pemanfaatan limbah serabut kelapa dan kombinasi kulit sapi memiliki nilai estetika yang baik sebagai bahan baku dan kombinasi pada pembuatan tas ataupun benda lainnya.
A STUDY OF COMPETENCE MODEL FOR FIVE-YEAR JUNIOR COLLEGE STUDENTS TAKING INTERNSHIP IN HAIRDRESSING INDUSTRY
Authors: Yeh Ju-Hsuan , Chou Yen-Fei
Published: May 2023

The paper aims to analyze the competence model for vocational college students taking internship in hairdressing industry based on the viewpoints of learning by doing, based on the discourses from Dewey’s experience theory and to understand the correlation and hierarchy of the context of competence for the professional skills of hairdressing industry, thereby to facilitate the design and development of human resources for the hairdressing industry. The study analyzes the off-campus interns for junior college cosmetology andhairdressing related departments in Taiwan. The study also emphasizes on school teachers, hairdressing personnel and hairdressing industry interns through conducting qualitative research document analysis, and quantitative research ISM system. The analysis of context and correlation of competence skills for hairdressing industry can be adopted as the standard of occupational information for designing hairdressing competence and learning map by schools and vocational institutes. Secondly, the study will link hairdressing personnel development with hairdressing industry demand to create win-win situations for school course instrument, industry education training and employment of industry personnel.
PENGARUH ZAT WARNA ALAM (ZWA) TERHADAP KUALITAS HASIL ECOPRINT TEKNIK STEAM BLANKET
Authors: Khasanah Asha , - Widowati
Published: May 2023

Banyaknya masalah dikarenakan limbah tekstil mendorong industri untuk menerapkan eco fashion. Langkah yang potensial adalah dengan teknik ecoprint. Ecoprint adalah proses pentransferan warna dan bentuk ke kain melalui kontak langsung. Ecoprint dalam penelitian ini menggunakan teknik steam medium print dengan beberapa zat warna alam, yakni secang, tingi, tegeran, kulit manggis dan merr. Tujuan penelitian ini untuk mengetahui pengaruh zat warna alam terhadap kualitas hasil ecoprint pada aspek warna dan motif. Penelitian ini menggunakan metode eksperimen. Observasi dilakukan melalui uji laboratorium dan uji organoleptik dengan sampel Klaster Batik Kota Semarang. Teknik analisis data menggunakan statistik deskriptif dan inferensial. Analisis arah warna pada latar menunjukkan bahwa zat warna secang memperoleh warna peach-punch, tingi memperoleh warna tangerine-ginger, tegeran memperoleh warna blonde-lemon, kulit manggis memperoleh warna egg nog-sand, dan merr memperoleh warna daffodil-mustard. Uji grey scale menunjukkan bahwa tidak ada pengaruh yang signifikan. Sedangkan uji staining scale dan estetika motif menunjukkan ada pengaruh yang signifikan. Hasil uji grey scale dan staining scale terbaik diperoleh zat warna kulit manggis dengan ratarata 4,17 (baik) dan 4,25 (baik). Sedangkan estetika motif terbaik diperoleh zat warna tegeran dengan rata-rata 3,97 (cukup baik).
Reality Not Imagination: Konseling Reality Therapy Membantu Penyesuaian Akademik
Authors: Ridha Andi Ahmad
Published: May 2023

Iklim akademik di perguruan tinggi menuntut mahasiswa memiliki penyesuaian diri yang mumpuni. Namun, tidak menutup kemungkinan terdapat mahasiswa yang kurang adaptif sehingga memengaruhi pencapaian prestasi akademiknya. Konseling dengan pendekatan reality therapy dapat digunakan untuk membantu mahasiswa menjadi pribadi yang lebih bertanggung jawab. Penelitian ini bertujuan untuk mengetahui efektivitas konseling dengan pendekatan reality therapy dalam meningkatkan penyesuaian akademik mahasiswa. Penelitian ini menggunakan metode single case experimental design dengan perlakuan berupa pemberian konseling dengan pendekatan reality therapy terhadap seorang mahasiswa semester 5 yang mengalami hambatan penyesuaian akademik. Instrumen penelitian berupa skala penyesuaian akademik. Data dianalisis secara deskriptif dengan menggambarkan perubahan yang dialami subjek sebelum dan setelah mengikuti konseling. Hasil penelitian menunjukkan bahwa subjek mengalami peningkatan penyesuaian akademik setelah diberikan konseling dengan pendekatan reality therapy. Subjek mengalami kemajuan dalam memetakan target perkuliahan dan mampu menunjukkan kegigihan dalam meningkatkan penyesuaian akademik.Academic climate in Higher Education requires students to have a good adaptation, but it does not rule out the possibility that there are students who are less adaptive and thus affect their academic achievement. Counseling with the reality therapy approach can be used to help students become more responsible individuals. This study aims to determine the effectiveness of counseling with the reality therapy approach in improving student academic adjustment. This study used a single case experimental design method with the treatment in the form of giving counseling with a reality therapy approach to a 5th semester student who experiences obstacles in academic adjustment. The research instrument is an academic adjustment scale. Data was analyzed descriptively by describing the changes experienced by the subject before and after taking counseling. The results showed that subjects experienced an increase in academic adjustment after being given counseling with the reality therapy approach. Subject made progress in mapping the target lectures and were able to show persistence in improving academic adjustment.
Apakah Kecerdasan Spiritual Memberi Pengaruh Terhadap Stress Tolerance? Studi Pada Mahasiswa Pendidikan Dokter
Authors: Sari Andina Felyana , Rizki Binta Muâ€™tiya , Haris Ajeng Octaviani Insani
Published: May 2023

Proses penyesuaian diri, manajemen waktu, dan beban akademik merupakan stressor bagi mahasiswa Pendidikan Dokter di tahun pertama. Beberapa penelitian sebelumnya juga menyebutkan tingkat stres pada mahasiswa kedokteran tergolong tinggi dibanding dengan program studi lainnya di sektor non-medis. Hal tersebut tentunya akan meningkatkan stres/permasalahan besar bagi mereka apabila tidak berusaha untuk meningkatkan kemampuan individu dalam menghadapi stres (stress tolerance). Usaha individu dalam meningkatkan stress tolerance dapat dilakukan melalui kecerdasan spiritual. Penelitian ini bertujuan untuk mengetahui pengaruh kecerdasan spiritual terhadap stress tolerance mahasiswa tahun pertama Pendidikan Dokter. Penelitian ini menggunakan metode kuantitatif korelasional dan subjek dalam penelitian ini adalah 167 mahasiswa tahun pertama Pendidikan Dokter di Semarang. Data diambil dengan menggunakan skala stress tolerance dan skala kecerdasan spiritual. Data diolah menggunakan analisis regresi sederhana. Hasil analisis data menunjukkan taraf signifikansi 0.000 (p 0.05). Hipotesis penelitian ini diterima yaitu kecerdasan spiritual memberikan pengaruh terhadap stress tolerance mahasiswa Pendidikan dokter di Semarang. Selanjutnya, hasil perhitungan R Square menunjukkan kontribusi kecerdasan spiritual adalah sebesar 31,3% terhadap toleransi stres.Problem in adaptation, time management, and academic load are stressors that are experienced by many medical students in their first year. Several previous studies also stated that stress on medical students was high compared to other study programs in the non-medical sector. This certainly will increase stress/ problem for them if they didn't try to improve their individual's ability to deal with stress (stress tolerance). Individual efforts to increase stress tolerance can be done through spiritual intelligence. This study aims to determine the effect of spiritual quotient on stress tolerance in first year students of the Medical Education. This research employs correlational quantitative methodology and the subjects in this study are 167 first-year students of medical education in Semarang. Data were collected using a stress tolerance scale and a spiritual quotient scale. The data were processed using simple regression analysis. The results of data analysis showed significance level of 0.000 (p 0.05), meaning that the hypothesis is accepted, that spiritual quotient has an effect on stress tolerance of first year students of the Faculty of Medicine in Semarang. Furthermore, the results of the calculation of R Square shows that the spiritual quotient contributes 31.3% to the stress tolerance.Â
Soziale Herkunft: Durch Bildung zu beruflichem (Top-)Erfolg?
Authors: Ehrmann Thomas , Prinz Aloys
Published: May 2023

Unter Nutzung des Skill-Paradoxons zeigen wir, dass durch die Ausweitung der universitären Ausbildung auf Nichttarget-Universitäten und steigende Ausbildungsqualität dieser Universitäten die Chancen von Bewerbern mit sozial schwächerer Herkunft bei der Besetzung von Spitzenpositionen in Unternehmen nicht notwendigerweise verbessert werden; sie können sich möglicherweise sogar verschlechtern. Diese Hypothese wird mit kostentheoretischen Überlegungen zur Personalauswahl unterstützt. Daran anschließend werden empirische Ergebnisse für das Investmentbanking in Großbritannien präsentiert.
SCENARIO BASED MACRO ASSESSMENTS OF THE POST-WAR RECOVERY OF UKRAINE'S ECONOMY
Authors:   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Skrypnychenko Mariya , Kuznietsova Lidiya ,   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Bilotserkivets, Oleksandr ,   State Institution “Itnstitute for Economics and Forecasting, NAS of Ukraine”
Published: May 2023

The article outlines the long-term trends in the development of the world economy against the background of the sharp deterioration in the conditions of global growth, primarily due to the ongoing war in Ukraine, persisting inflation and tightening financial conditions. A special place is given to the main task of the post-war reconstruction of Ukraine’s economy, which is the transition from the pre-war commodity-agrarian, and import-dependent economy and ensuring economic recovery based on modern achievements in science, technology and the new technological order. Completing the task includes the restoration of infrastructure, restructuring the economic sectors and activities that should become drivers for the recovery of Ukraine's economy in the near future (defense-industrial complex, agricultural sector, construction, ICT sector, and mechanical engineering), preservation of human capital, etc. The authors note that in 2022, a significant drop in output in all economic activities is expected, which will persist until the end of hostilities. Construction, whose activities will be limited to the restoration of destroyed critical infrastructure, and industry, which accounted for the lion's share of Ukraine's pre-war industrial production (mining, metallurgy, energy), will experience the biggest decline. The starting conditions of the forecast estimates of Ukraine's post-war recovery are identified, such as investment attraction, a high rate of accumulation of fixed capital to provide a shorter period of economic recovery, and achieving a moderate inflation. Calculations show that attaining the rate of gross accumulation of fixed capital up to 30-35% of GDP would contribute to a rapid recovery of Ukraine's economy after the war. It is shown that the main factors of the decrease in merchandise exports during the war are the drop in output and the erosion of this country’s transport and logistics potential. An assessment is made of the value and physical volumes, as well as the commodity and geographical structure of merchandise exports from Ukraine in 2022. The authors also provide an assessment of the impact of the reduced physical volume of merchandise exports on output, value added and labor wages in Ukraine. The risks of ensuring the post-war recovery of Ukraine's economy are identified, the main of which are the continuation of the military aggression by the Russian Federation after 2023 and the escalation of hostilities on the territory of Ukraine with a strengthening impact of destructive shocks from the global recession on this country’s domestic economic processes.
Самоменеджмент в контексті розвитку професійної кар’єри державних службовців
Authors: Рачинський Анатолій
Published: May 2023

In the article, the author reveals important aspects of the modern paradigm of the development of public administration, which requires new approaches to solving the problems of professionalization of the public service. The author attaches great importance to the issue of effective career development management of civil servants. After all, for modern Ukraine, which is under martial law as a result of Russia's large-scale war on the territory of Ukraine, this problem takes on special importance in the perspective of obtaining the status of a candidate country for EU membership.

In recent years, ideas about career have changed fundamentally, in particular, it is perceived as an opportunity to realize one's own professional development, to use personal reserves (potentials) for real awareness of one's abilities. According to the author, it is in the process of professional development of civil servants that the issue of career planning skills formation is actualized, which is implemented in determining career development goals and ways to achieve them.

The author actualizes the attention of scientists on professional career development, they refer the actions of employees to implement their plan as a planning and management of career development, which brings a number of advantages to both the official himself and the organization in which he works.

The author emphasizes that the problem of ensuring the interaction of professional and intra-organizational careers is of particular importance in the professional activity of civil servants. This interaction requires the fulfillment of a number of tasks: achieving the interdependence of the goals of a state institution/organization and an individual civil servant; ensuring orientation of career planning to a specific civil servant in order to take into account his personal needs; ensuring the transparency of the career management process; creation of clear criteria for professional development; examination of the professional potential of civil servants, etc.
Aloe gel: manipulation and characterization of physical-chemical quality adjustment
Authors: Mendes Aciole Italy Heibe , De Andrade Júnior Francisco Patricio , Vilar Cordeiro Laísa , Pereira de Souza Júlia Beatriz
Published: May 2023

The objective of the study was to develop and characterize the gel based on Aloe vera for the Manoel Casado de Almeida Pharmacy School. The research was done at the Education and Health Center off the Federal University of Campina Grande, located in the city of Cuité (PB). For the quality control, chemical physical tests were carried out as determine pH, apparent density, viscosity, spreadability and centrifugation test. The gel demonstrated acceptable physicochemical characteristics exhibiting pH 5, bulk density 0.1018 (± 0.0008), viscosity above 10 000 cP, and adequate stability. Complementary studies on microbiological quality are suggested, to give safety on their therapeutic potential in wound management.
Luliconazole: Stability-indicating LC method, structural elucidation of major degradation product by HRMS and in silico studies
Authors: Porto Douglas dos Santos , Bajerski Lisiane , Malesuik Marcelo Donadel , Braun Azeredo Juliano , Paula Fávero Reisdorfer , Soldateli Paim Clésio
Published: May 2023

Aim: A new stability-indicating liquid chromatography method was developed and validated for the quantitative determination of luliconazole. Materials and methods: Preliminary forced degradation study demonstrated an additional peak of the degradation product at the same retention time to the drug, due to this, the method was developed optimizing the chromatographic conditions to provide sufficient peak resolution (R ≥ 2). The experimental design was evaluated to assess the robustness and the best chromatographic conditions to be used for the validation. Methodology: Luliconazole solutions were exposed to various stress conditions to evaluate the method indication stability, in which the degradation product (DP-1) formed was isolated, identified, and evaluated in silico to predict degradation pathway and toxicity. The procedure was validated by robustness, selectivity, linearity, precision, and accuracy. Liquid chromatography was performed in a Phenomenex® RP-18 column with a mixture of acetonitrile and 0.3% (v/v) triethylamine solution as a mobile phase in isocratic elution. Results and conclusions: The method demonstrated robustness, good recovery, precision, linear response over a range from 5.0 to 40.0 μg.mL-1, and to be stability indicating. The alkaline stress condition resulted in the formation of DP-1. hrms studies identified this product as an hydroxyacetamide derivative, and in silico studies did not show toxic potential.