bluuebunny/crossref_metadata_2025 huggingface dataset:
Selection of potato varieties in the cultivation of two crops in the Central Non-Chernozem region
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Gasparyan I. N. , Levshin Alexander G. , Ivashova Olga N. , Deniskina Natalia F. , Gasparyan Shagen V.
Published: November 2023

The development of potato plants when cultivating two crops occurs in a short period. In this case, field conditions change and do not repeat over time. Crop formation when cultivating two crops in the Central Non-Black Earth Region finds itself in different growing conditions: the first harvest falls on long days and moderate temperatures, as well as sometimes returning frosts, the second harvest falls on short days and high temperatures, as well as lack of moisture. The purpose of our research was to substantiate the choice of varieties for cultivating two crops. The research was carried out at the Research and Production Center Vegetable Experimental Station of the Federal State Budgetary Educational Institution of Higher Education RSAU-MAA named after C.A. Timiryazev, Moscow and at the Central Experimental Station of the All-Russian Research Institute of Agrochemistry Barybino, Moscow Region, 2017‑2022. The experiment was carried out using the method of random placement of plots. Planting density – 47.6 thousand plants per 1 hectare. Sprouted tubers were used for planting during the first planting of the large fraction; during the second planting, the middle fraction was germinated with the addition of dry hydrogel. The second planting was carried out in the vacant space after the first planting had been cleared. The cultivation technology is standard. Cleaning took place at the beginning of July and at the end of September. As a result of the study ni different climatic conditions, it was revealed that planting of 1 crop should be carried out with ultra-early ripening varieties (Riviera) and for 2 crops with mid-early and mid-ripening varieties (Udacha).
Specification of parameters of extreme summer precipitation for the design and operation of hydraulic structures in small catchments of the Central Chernozem (Black Earth) zone of Russia
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Naumova Anna A.
Published: November 2023

The main goal of the research is to clarify the parameters of extreme summer precipitation for the design and operation of hydraulic structures in small catchments. Having data on 12 meteorological stations of the Central Black Earth Zone of Russia, observations of phase-homogeneous values that were of genetically homogeneous origin were selected to assess the degree of variability of extreme precipitation. Statistical methods were used both in the presence and insufficiency of observational data. In the conditions of changing climatic factors and the lack of sufficiently accurate methods for determining the asymmetry coefficient, approaches to its determination using the method of year-points for the territory of the Central Black Earth Zone of the Russian Federation were proposed. Existing regulations, in which extreme precipitation is the basis for determining maximum discharges, lose their initial reliability and have shortcomings in the methods for determining hydrometeorological characteristics. Accordingly, the need to update the existing regulatory documents in connection with the trend of increasing the values of summer extreme precipitation relative to the region under consideration is substantiated.
ИССЛЕДОВАНИЕ ВЛИЯНИЯ ЗАМЕЩЕНИЯ КАТИОНА НА СТРУКТУРУ ГАЛОГЕНИДНЫХ ПЕРОВСКИТОВ НА ОСНОВЕ ТЕОРИИ ФУНКЦИОНАЛА ПЛОТНОСТИ И МОЛЕКУЛЯРНОЙ ДИНАМИКИ
Authors: Нургалиев И.Н. , Марасулов М.Б. , Ашуров Н.Р.
Published: November 2023

За последние несколько лет технические усовершенствования составов и процедур изготовления солнечных элементов на основе перовскитов привели к значительному повышению их эффективности преобразования энергии. С помощью теории функционала плотности (ТФП) и молекулярной динамики (МД) теоретически исследованы кристаллическая, электронная структура и процесс ионной диффузии в частично замещенного кубического метиламмонийного (МА) перовскита на основе галогенида свинца MA0,5X0,5PbI3, где Х – катион. Электронная структура исследованных частично замещенных перовскитов подобна структуре MAPbI3, однако ширина запрещенной изменяется по сравнению со структурой MAPbI3. Частичное замещение MA вызывает искажение решетки, что приводит к предотвращению диффузии MA или X между узлами A в кристалле перовскита. Показано, что частичное замещение катиона влияет на электронную структуру и искажает кристаллическую решетку перовскита, что позволяет управлять оптическими свойствами материала в разных областях спектра и влиять на электронный состав дефектов.
Pengaruh Penambahan Nanopartikel Seng Oksida (ZnO) terhadap Kekuatan Mekanik Semen Kedokteran Gigi: Telaah Sistematis
Authors: Hartanto Ardelina C , Situmorang Evi UM , Octavia Mora
Published: November 2023

Salah satu masalah gigi adalah karies gigi atau gigi berlubang. Mengatasi karies gigi bisa dengan restorasi gigi. Salah satu bahan restorasi adalah semen kedokteran gigi yaitu semen gigi seperti seng fosfat, semen polikarboksilat, semen ionomer kaca (GIC), serta semen seng oksida dan eugenol (ZOE). Tetapi semen gigi memiliki kekuatan mekanik yang rendah sehingga memerlukan bahan tambahan untuk meningkatkan kekuatan mekanik semen gigi tersebut, seperti dengan menambahkan nanopartikel Seng oksida (ZnO). Tujuan penelitian ini untuk mengetahui pengaruh penambahan massa nanopartikel ZnO terhadap kekuatan tekan dan kekerasan semen kedokteran gigi. Penelitian ini menggunakan metode penelitian menggunakan telaah sistematis dengan memasukkan kata kunci pada database Google Scholar, Pubmed, ProQuest dan Science Direct  dengan rentang waktu 2011-2021. Telaah sistematis ini dibuat berdasarkan guideline PRISMA-P dan dievaluasi dengan kriteria JBI Critical Appraisal tools.  Kriteria inklusi pada penelitian ini adalah seluruh studi eksperimental yang sesuai dengan topik penelitian. Hasil menunjukkan bahwa kekuatan tekan dan kekerasan semen gigi terus meningkat seiring penambahan massa nanopartikel ZnO. Hal ini disebabkan karena partikel berukuran nano dapat mengisi ruang kosong antar partikel semen yang berukuran besar saat berikatan, juga meningkatkan ikatan interlock menjadi lebih kuat dan lebih homogen. Dapat disimpulkan terdapat pengaruh penambahan massa nanopartikel ZnO terhadap kekerasan dan kekuatan tekan semen kedokteran gigi.
A Case of Pure Red Cell Aplasia as a Possible Complication of Pulmonary Tuberculosis Treatment
Authors: Tanuatmadja Abram P , Kwee Limdawati , Tan Fellicia , Sanjaya Ardo , Gunadi Julia W
Published: November 2023

Pure red cell aplasia (PRCA) is a rare disorder caused by failure or abnormalities in erythropoiesis only, among all cell lines of the bone marrow. Patients with PRCA usually present with no specific clinical presentation, thus its recognition depends on a clinician’s high index of suspicion, to facilitate early diagnosis and treatment to provide a better prognosis. Tuberculosis (TB) is the infectious disease with the highest casualty rate worldwide and is still a problem in many countries, including Indonesia. This study is a case report of a pulmonary TB patient with PRCA as a complication. PRCA was confirmed by the bone marrow puncture (BMP) examination as the gold standard. In this case, PRCA was inferred to occur due to the use of Isoniazid in the TB treatment regimen. The discontinuation of Isoniazid administration subsequently results in the normalization of Hb levels. In this paper we would highlight PRCA as a differential diagnosis that should be taken into consideration in symptomatic anemia in patients with tuberculosis under standard treatment.
The Effect of Turmeric and Mangosteen Peel Extract on PPARα Gene Expression in the Retina of HFD-Induced Rat Model
Authors: Noor Yenny , Jasaputra Diana K , Gunadi Julia W , Lesmana Ronny , Safira Riska A
Published: November 2023

A long-term high-fat diet (HFD) was proven to induce metabolic dysfunction and causes various organ inflammation, including the retina. As the regulator of lipid metabolism, PPARa plays a role in retinal lipid metabolism and served as one of the targets for decreasing lipid deposition in the retina. Turmeric and mangosteen peel are Indonesian medicinal herbs with enormous health effects, including antiinflammation and hypolipidemic properties. This study aims to determine the effect of ethanol extract from turmeric and mangosteen peel on PPARa  gene expression in the retina of an HFD-induced rat model. Twenty male Wistar rats were divided into 5 groups: negative control, positive control, turmeric, mangosteen, and fibrate. At the end of the study, total cholesterol and triglyceride levels from the blood were measured. The retina was extracted to conduct Realtime PCR for PPARα gene expression. The result showed a significant difference in triglyceride levels between positive control and turmeric groups, and PPARa gene expression in the retina between the control negative, positive, and turmeric groups, but no significant difference was found in other groups. This study concludes that the extract of turmeric increases the expression of the PPARa gene expression in the retina in an HFD-induced rat model.
Effectiveness of antibiotic ointment and eye drop therapy for the treatment of chlamydiosis in cats
Authors: Raida Raisatulhaq  , Hiroyuki Andi , Lestari Nurul Aeni Ayu
Published: November 2023

Chlamydophila felis is one of the most common pathogenic agents causing conjunctivitis in cats and is commonly referred to as chlamydiosis. This paper reports the effectiveness of topical treatment using antibiotics in the form of eye ointment and eye drops in a cat with a case of chlamydiosis. Clinical signs in cats include conjunctivitis, mucopurulent ocular discharge followed by nasal discharge. Treatment begins with administering eye ointment until the condition improves within 6 days and treatment switches to using eye drops. The results of the treatment showed that administering topical medication in the form of an ointment provided fairly good healing results within 6 days, while eye drops appeared to be ineffective where the conjunctivitis became worse after 3 days of treatment. The cat was then treated with enucleation on the 9th day because the disease condition had an infaustal prognosis.
Uso na ventilação não invasiva na sobrevida de pacientes com esclerose lateral amiotrófica
Authors:   , barros vynicius
Published: November 2023

Resumo
Introdução: A esclerose lateral amiotrófica (ELA) também chamada de doença do neurônio motor (DNM) é uma doença rara, degenerativa, progressiva até então sem cura, que afeta os neurônios motores, tanto os superiores quanto os inferiores, trazendo dificuldades à qualidade de vida de indivíduos portadores. Diante desses casos o uso de ventilação não invasiva (VNI) para atenuar os sintomas respiratórios vem se tornando cada vez mais comum, com um aumento significativo da sobrevida e qualidade de vida. Objetivo: O uso da ventilação mecânica não invasiva VNI na sobrevida e qualidade de vida em pacientes com esclerose lateral amiotrófica. Metodologia: Trata-se de uma revisão de literatura, realizada por meio de bancos de dados científicos nas línguas portuguesa e inglesa: Scielo e Pubmed/Medline entre os anos de 2017 e 2023. Resultados/Considerações finais: A esclerose lateral amiotrófica é uma doença neurodegenerativa progressiva com acometimento muscular, em especial a musculatura respiratória, contudo a VNI se demonstrou ser uma boa opção de tratamento dos sintomas respiratórios como hipoventilação alveolar e hipercapnia.

Palavras – chaves: fisioterapia, Esclerose lateral Amiotrófica, Insuficiência Respiratória, Sobrevida e Ventilação não invasiva.
APLICABILIDADE DA LEI LUCAS NAS ESCOLAS PÚBLICAS E PRIVADAS DO MUNICÍPIO DE PAU DOS FERROS/RN
Authors: Barreto Fernanda Flavia de Freitas , Costa Ana Beatriz , Carvalho Ana Beatriz Morais de , Silva Danilia Carlos da , Silva Daniele Carlos da , Alves Emilly Gabriela Holanda , Monteiro Jefferson Carlos , Pessoa Lorena Monteiro , Dantas Marciano Ferreira , Maia Nathália Wygna Monteiro , Alves Maria Vitoria
Published: November 2023

Este trabalho tem como objetivo investigar o cumprimento da Lei Lucas nas instituições educacionais públicas e privadas do Município de Pau dos Ferros, visando a importância de capacitar esses profissionais nas escolas, para a realização qualificada do atendimento pré-hospitalar. Acredita-se que ao divulgar informações corretas sobre os primeiros socorros para os professores, esses possam desenvolver um atendimento mais racional e eficaz, evitando a utilização de práticas inadequadas às crianças acidentadas. Foi realizado um estudo para a familiarização do grupo com os dados que eram pouco conhecidos e sistematizados daquela instituição. Tendo em vista que a Lei nº 13.722 estabelece a obrigatoriedade da “capacitação em noções básicas de primeiros socorros de professores e funcionários de estabelecimentos de ensino públicos e privados de educação básica e de estabelecimentos de recreação infantil”. Portanto, após o desenvolvimento de todo o projeto, com as práticas e o desenvolvimento das demais atividades a qual o projeto esteja proposto, assegura-se que o objetivo proposto foi alcançado, visto que os profissionais foram capacitados através de treinamentos, em que foi ofertado conhecimentos através da teoria e da prática.
Teoria e discurso nas ciências sociais
Authors: Magalhães Filho Glauco Barreira
Published: November 2023

O paradigma metodológico ligado à tradição alemã nas ciências sociais, com referência a pensadores como Georg Simmel, Max Weber e Norbert Elias, é considerado de grande fertilidade. A abordagem alemã valoriza a compreensão e interpretação dos fatos sociais em vez de uma análise estritamente causal. Essa perspectiva reconhece que os fatos sociais têm significado quando conectados aos motivos que guiam a ação dos indivíduos. A empatia desempenha um papel fundamental nessa abordagem, permitindo que os pesquisadores se identifiquem emocionalmente com os atores sociais para melhor compreender suas perspectivas. A construção do conhecimento social requer uma compreensão profunda dos motivos e uma capacidade de interpretar relações complexas. A teoria sociológica deve ser vista como um campo de argumentação multiparadigmático e multimetodológico, promovendo uma concepção pluralista em relação a regras e procedimentos. A relação entre ciência social e hermenêutica é crucial, uma vez que a compreensão das ações humanas requer uma interpretação profunda e contextualizada. A abordagem de campo, proposta por Pierre Bourdieu, sugere que os campos científicos são microcosmos autônomos que operam dentro do macrocosmo social, influenciados por suas próprias leis e pressões externas. A comunicação oral do discurso científico envolve técnicas retóricas para persuasão e clareza, incluindo o uso de ethos, pathos e logos. A organização do discurso também é fundamental para manter o foco e a clareza. Em resumo, essa abordagem metodológica alemã valoriza a compreensão, a interpretação, a empatia e a construção ativa do objeto de estudo. Ela reconhece a importância do contexto, da interdisciplinaridade e da comunicação eficaz para a construção do conhecimento nas ciências sociais.
A prática da "rachadinha" no contexto brasileiro: crime, improbidade administrativa ou fato atípico?
Authors: Lopes Mateus Venícius Parente , Marques Junior William Paiva
Published: November 2023

O capítulo em apreço tem como escopo abordar temática objeto de discussão no âmbito da doutrina e da jurisprudência brasileira: o repasse indevido de vencimentos de servidores de cargos em comissão a servidores públicos hierarquicamente superiores. A finalidade do presente trabalho é examinar como tal prática, denominada de “rachadinha”, vem sendo encarada pelos juristas nacionais, tanto em nível doutrinário como jurisprudencial. Este trabalho consiste em pesquisa descritiva (quanto ao objetivo), bibliográfica (quanto ao procedimento) e qualitativa (quanto à abordagem). Conclui-se que não há uma pacificação acerca do assunto abordado, havendo dissonância de entendimentos quanto à natureza jurídica da repressão a ser promovida: se criminal, se administrativa ou, ainda, se mero fato indiferente penal. As decisões proferidas em sede dos Tribunais Superiores têm variado conforme o contexto levado ao conhecimento da respectiva Corte.
Sistema Interamericano de Direitos Humanos e a violência de gênero contra a mulher: caso Maria da Penha
Authors: Barbosa João Paulo de Carvalho
Published: November 2023

A Proteção Internacional dos Direitos Humanos ganha força no cenário pós-Segunda Guerra Mundial, dada a gravidade das violações dos direitos fundamentais e das atrocidades cometidas. Reconhecendo as especificidades e a situação de vulnerabilidade da mulher, emerge a necessidade de proteção específica. Dentre os documentos que se destacam na Proteção Internacional dos direitos humanos (e da mulher) merecem destaque o Sistema Interamericano de Direitos humanos e a Convenção Interamericana para Prevenir, Punir e Erradicar a Violência Contra a Mulher (Convenção de Belém do Pará). Dessa forma, o Brasil assume um compromisso internacional no combate à violência contra a mulher e contra toda forma de discriminação baseada no gênero (dentre outras) tanto na esfera pública quanto privada. Apesar da criação da Lei n° 11.340 de 2006 ainda é possível observar a necessidade de aplicação de políticas públicas efetivas para promoção e proteção dos direitos humanos da mulher e se alcance a efetivação do direito fundamental à igualdade de gênero.
ANXIETY IN JOHN GREEN’S NOVEL THE FAULT IN OUR STAR
Authors: Zamzami Anastasya Al , Wulan Sri
Published: November 2023

This study aims to reveal the type of anxiety experienced by the protagonist and her defense mechanisms against the anxiety in John Green’s novel The Fault in Our Star. The causes of anxiety can be seen for the first time when Hazel is diagnosed with thyroid cancer. That situation results in a big impact on people around her, especially her parents' boyfriends. They get worried that she will hurt the people around her. This study uses the psychoanalytic theory of Sigmund Freud to explain the protagonist's type of anxiety and her defense mechanisms to get rid of the anxiety. In completing the analysis, this study applies the qualitative research method because the data collected in this study are in the form of words as quotations taken from the source. The results of this study indicate that the first protagonist's anxiety is caused by feeling guilty, overthinking, and worrying about keeping an eye out for the future. Therefore, two types of anxiety can be found in the novel. They are moral and realistic anxieties. Then, the protagonist commits two defense mechanisms to avoid her anxiety. They are rationalization and reaction formation. Finally, this data proves that the protagonist in the novel suffers from anxiety, and she tries hard to cure the disease.
SPEECH ACTS IN THE WEDDING OF BATAK TOBA ETHNIC AT JANGGA TORUAN VILLAGE, KECAMATAN LUMBAN JULU KABUPATEN TOBA SAMOSIR
Authors: Manurung Linarti , Matondang Saiful Anwar , Pawiro Muhammad Ali
Published: November 2023

The marriage of the Batak Toba community is closely related to the role of Dalihan Na Tolu, something that cannot be separated from Batak Toba customs because Dalihan Na Tolu is a symbol of the social system of the Batak Toba people, which has three pillars consisting of Hula-hula, Dongantubu, and Boru. The function of Dalihan Na Tolu, besides assisting the respective relatives, also plays a role in providing the materials for carrying out traditional Batak Toba weddings. The purpose of this research is to describe the implementation of speech acts in the wedding of the Batak Toba indigenous people and also to describe the types of speech acts in the Batak Toba wedding. In this case, the theory of speech acts is taken from Austin, which is then developed by Searle. The method used is a descriptive qualitative method supported by data analysis techniques based on the information given by the community leaders in the village of Janggatoruan, Kecamatam, Lumban, Julu, Kabupaten, and Toba Samosir. The findings of this study are of four speech acts in the wedding: 1) representative speech acts; 2) expressive speech acts; 3) directive speech acts; and 4) declarative speech acts.
EXISTENTIALIST FEMINISM IN MOMMY ASF'S NOVEL LAYANGAN PUTUS
Authors: Sitepu Eka Putradyn KJ , Pawiro Muhammad Ali , Siwi Purwanto
Published: November 2023

The research is concerned with women's movements portrayed in Mommy Asf’s novel Layangan Putus. It objectively finds and discusses a mother's individual movements through transcendence to upholster her existence, particularly in an attempt to overcome and improve herself even without a husband's support, as shown by Kinan, the main female character in the novel. The fact that a woman is always marginalized based on social reality, especially a woman,  becomes the background of the study. The research is conducted using the descriptive-qualitative method proposed by Creswell. The theory applied in this research is the sexist feminist theory proposed by Simone de Beauvoir. The finding concerns the woman's movements described in the novel using Beauvoir's existentialist feminism. The results show that Kinan,  as the main female character,  can overcome and improve herself in life, as evidenced by the four transcendences of Beauvoir's theory to uphold her existence as a manifestation of Owen's movements: Kinan is able to work, become intellectual, achieve social transformation, and refuse the role of otherness
Questioning Strategy That Works to Foster Critical Thinking Skills: A Study In Islamic University
Authors: Rasyid Fathor , Aini Nurul , Varghesse KJ
Published: November 2023

The aim driving the study is to develop instructional strategies that best fit students to enhance higher order thinking skills through questioning strategy. A university class consisting of thirty students is taking part in the study on Quantitative Research Methodology. The study is classroom action research with two steps. Preliminary study reveals that students had insufficient understanding towards HOTS (Higher Order Thinking Skills) and needed awareness raising towards critical thinking. A questioning strategy-based lesson plan, observation sheets, and critical thinking questionnaire were developed based on a questioning strategy approach. The findings indicate that the questioning strategy significantly enhances critical thinking skills. This result suggests teachers use questioning strategy to assist students' progress critical thinking. The implication of the study is that teachers should have the HOTS to facilitate and cultivate critical thinking among students and establish a thinking-oriented classroom
IMPLEMENTASI MODEL SURVEY QUESTION READ RECITE AND REVIEW (SQ3R) UNTUK MENINGKATKAN AKTIVITAS BELAJAR PERUBAHAN SOSIAL BUDAYA BANGSA INDONESIA DALAM MENGAHADAPI ARUS GLOBALISASI DI KELAS IX.G SMP NEGERI 2 SIBOLGA
Authors: Banjarnahor Parasian
Published: November 2023

Proses Pembelajaran Mata Pelajaran Ilmu Pengetahuan Sosial sebagian besar dilaksankan dengan  menggunakan pendekatan konvensional dengan menggunakan ceramah sebagai metode utama yang digunakan untuk menyampaikan materi pelajaran. Dengan pendekatan ini proses pembelajaran berjalan dengan satu arah, sehingga siswa aktivitas belajar siswa hanya mendengarkan dan mencatat (siswa pasif). Penulis memilih pendekatan Survey, Question, Read, Recite, Review (SQ3R)  agar pembelajaran menjadi aktif dan melibatkan siswa secara langsung dalam pembelajaran. Sehingga tujuan pembelajaran yang diharapkan mudah tercapai. Penelitian tindakan kelas ini menjelaskan Model SQ3R untuk meningkatkan aktivitas  belajar siswa Perubahan Sosial Budaya Bangsa Indonesia Dalam mengahadapi Arus Globalisasi di kelas IX.G SMP Negeri 2 Sibolga  Semester ganjil Tahun Pelajaran 2021/2022. Penelitian Tindakan Kelas ini dilakukan dalam empat  kelompok kegiatan yang meliputi  : Kegiatan perencanaan tindakan, Pelaksanaan  tindakan, Observasi dan Refleksi.

Hasil penelitian menunjukkan bahwa pembelajaran dengan menggunakan Model SQ3R terjadi adanya peningkatan aktivitas belajar 43.66 %, yang memberikan dampak terhadap peningkatan hasil belajar hingga mencapai rata-rata kelas :  80.37 yang semula 59.67. Kriteria Ketuntasan Minimal (KKM) adalah 75. Dari hasil isian angket yang diberikan kepada 30 siswa menyatakan bahwa  proses belajar mengajar menggunakan Model SQ3R, 100% responden menyatakan bahwa  lebih jelas dan menyenangkan.Kesimpulan  penulis  bahwa Model SQ3R merupakan  model pembelajaran yang tepat untuk meningkatkan aktivitas belajar  siswa materi Perubahan Sosial Budaya Bangsa Indonesia Dalam mengahadapi Arus Globalisasi  di kelas IX.G SMP Negeri 2 Sibolga T.P. 2021/2022
Phytotherapy (BNO 1045) of Acute Lower Uncomplicated Urinary Tract Infection in Women Normalizes Local Host Responses
Authors: Butler Daniel S. C. , Wagenlehner Florian , Höller Martina , Abramov-Sommariva Dimitri , Steindl Hubert , Naber Kurt G.
Published: November 2023

Acute lower uncomplicated urinary tract infection (uUTI) affects a large proportion of women. Increased antimicrobial resistance has created an urgent need for novel therapeutics and the phytotherapeutic drug BNO 1045 (Canephron® N) has previously been shown to be noninferior to standard antimicrobial stewardship. This sub-analysis from a randomized, double-blind, controlled phase III noninferiority clinical trial using BNO 1045 versus fosfomycin to treat uUTI aimed to determine how urine cytokine levels are altered by the two different treatments.
Methods. Urine samples from a predefined subset of women diagnosed with uUTI (18–70 years) and treated with BNO 1045 (n=58) or fosfomycin (n=69) were analyzed for urine levels of IL-6 and IL-8, using analyte-to-creatinine ratios.
Results. BNO 1045 treatment showed similar effects to fosfomycin treatment in reducing both urine IL-6 and IL-8 levels. Mean IL-6 and IL-8 levels were markedly reduced in all patients regardless of treatment. BNO 1045 treatment decreased urine IL-8 significantly (p=0.0142) and showed a trend toward reduction of urine IL-6 (p=0.0551). Fosfomycin treatment reduced both IL-6 and IL-8 levels significantly (p=0.0038, <0.0001 respectively).
Conclusion. BNO 1045 is, in addition to reducing symptoms, comparable to fosfomycin treatment in reducing the local inflammatory response associated with uUTI.
Analysis of Qualitative Disorders of Ejaculate of Infertile Men in the Framework of Preparation for the Program of Assisted Reproductive Technologies
Authors: Gontar Yuliia , Yasynetskyi Mykola
Published: November 2023

Assessment of the spermatogenesis has an important diagnostic value in various forms of reproductive dysfunction. For this purpose, a number of methods have been developed based on the study of the morphology of germ cells at different stages of their development.
Spermogram is the initial test for the laboratory diagnosis, which allows to evaluate the male reproductive function: the number of spermatozoa, their motility, viability and morphology. However, there is a need to develop an algorithm for the study of spermatozoa to obtain not only quantitative, but also qualitative indicators. Along with the standard spermogram, according to WHO recommendations from 2021, it is necessary to perform such analyzes as determining the levels of sperm DNA fragmentation and oxidative stress, detection of antisperm antibodies, etc.
The objective: to analyze the of qualitative violations of the ejaculate of infertile men who will be included in the program of assisted reproductive technologies (ART).
Materials and methods. During the study, ejaculate samples of 39 infertile men who will be included in ART were analyzed. The average age of the patients was 36.2±5.8 years. A spermogram was performed according to WHO recommendations from 2021, DNA fragmentation levels of spermatozoa were analyzed by the SCD method, and the presence of antisperm antibodies was determined by the method based on the precipitation reaction.
Results. The correlation between the level of DNA fragmentation of spermatozoa and the concentration of spermatozoa in the ejaculate was analyzed (Spearman’s r = –0.397; p<0.05). A correlation was found between the level of DNA fragmentation and the proportion of actively motile spermatozoa (r Spearman =–0.32; p<0.05). A direct correlation was determined between the level of fragmentation and the proportion of immotile male germ cells (r Spearman = 0.403; p<0.01), namely: with an increased number of immotile spermatozoa the percentage of cells with DNA fragmentation increases. Prescribing antibiotic therapy and antioxidants to both natural and in vitro fertilization patients has been shown to be beneficial, especially in individuals with a high percentage of DNA-damaged sperm.
Conclusions. The results of the study indicate the importance of a complex assessment of ejaculate parameters. Determination of interdependent indicators is an important approach for examination of men with fertility disorders of various genesis and an effective tool for diagnosis of qualitative disorders in ejaculate indicators.
Scoping Review The Effect of Finger Grip Relaxation on The Patient's Anxiety Level Before Operation
Authors: Anggraini Marcelis Stia , Hidayat Asri
Published: November 2023

Persiapan sebelum operasi merupakan tahap awal dari fase perioperatif. Tahap ini dimulai saat seseorang pasien di putuskan oleh dokter harus mendapatkan tindakan operasi sampai pasien berada di kamar operasi. Word Health Organisation (WHO) menyatakan, pasien yang menjalani tindakan operasi mengalami peningkatan di setiap tahunnya, tahun 2011 tercatat 140 juta jiwa pasien di Rumah Sakit seluru dunia yang menjalani tindakan operasi lalu meningkat di tahun 2012 menjadi 148 juta jiwa. Di Indonesia sendiri pada tahun 2012 tercatat 1,2 juta jiwa dan tindakan operasi mendapat urutan ke 11 dari 50 urutan penanganan pertama semua penyakit di seluru Rumah Sakit umum maupun swasta di Indonesa.Scoping review ini menggunakan framework PICOS. Melalui lima fase identifikasi, di mulai dengan menentukan pertanyaan scoping, mencari artikel yang sesuai, menyaring setiap artikel yang di temukan berdasarkan kriteria inklusi yakni original artikel, full text, terbit 5 tahun terakhir, open akses, serta berbahasa Indonesia dan Inggris sedangkan kriteria eksklusinya yakni buku dan artikel review,  mengelompokan dan meresume hasil temuan artikel, menyusun hasil dalam bentuk resume pembahasan. PRISMA flowchart digunakan untuk menampilkan alur pencarian evidence. Hasil review menunjukan terdapat 13 dari 5016 artikel yang di saring sesuai kriteria inklusi dan eksklusi. Review ini memunculkan empat tema yaitu prevalensi kecemasan sebelum operasi; factor yang mempengaruhi kecemasan pasien sebelum operasi; tingkat kecemasan yang di alami pasien; serta pengaruh dari relaksasi genggam jari dalam menurunkan kecemasan. Hingga kita simpulkan Terdapat pengaruh relaksasi genggam jari dalam menurunkan rasa cemas pada pasien yang akan menjalankan prosedur operasi.Kata kunci                      : Handgrib relaxation, hand messange, handheld relaxation, anxiety  levels, before sugery, pre operative.Kepustakaan                 : 13 artikel (2017-2021)
The Relationship of Preeclampsia and Eclampsia, Antepartum Haemorrhage and Anemia Mother with Apgar Score <7 Babies Born in RSUD Abdoel Wahab Sjahranie Samarinda
Authors: Rahman Mahy Ragib , Ngo Novia Fransiska , Wardhana Ahmad Wisnu
Published: November 2023

Background: Everyday 7,000 babies die worldwide, with 2,4 million babies dying in the first month of life. While in Indonesia 19 deaths per 1000 live births with the main causes of neonatal death in 2017 were complication related to premature birth (asphyxia or difficulty breathing at birth), infections, and births defects. Meanwhile, in East Kalimantan, the highest cause of death was dominated by low birth weight (LBW) followed by asphyxia neonatorum. The examination that is always used in newborns by health workers to assess the occurrence of distress respiration neonatal is to assess the APGAR score. The APGAR score reflects clinical signs of distress respiration neonatal, such as cyanosis or pallor, bradycardia, reflex response to stimuli, hypotonia, and apnea or dyspnea. Scores will be reported within the first minute and fifth minute after birth for all infants and thereafter at intervals of 5 minutes to 20 minutes for infants with a score below 7 (asphyxia). Preeclampsia and eclampsia, antepartum haemorrhage, and maternal anemia are factors that can affect the APGAR score which is one of the assessments of the diagnosis of neonatal asphyxia. Research Objectives: to determine the relationship between risk factors and APGAR scores below 7 (asphyxia) in Abdoel Wahab Sjahranie Hospital, Samarinda. Methods: The design of this study used case control using observational analytical methods. The sample was taken from the medical record data of mothers and children born at the Abdoel Wahab Sjahranie Hospital Samarinda for the 2019-2021 period as many as 65 cases and 65 controls. Result: Bivariate analysis was performed using the chi-square test. The results of the analysis showed that there was a relationship between preeclampsia (p=0.000), eclampsia (p=0.003), antepartum bleeding (p=0.001), and anemia (p=0.001) with an APGAR score below 7.Keywords:  APGAR score, preeclampsia, eclampsia, anemia, haemorrhage, asphyxia.
The Influence of Breastfeeding On Nutritional Status, and the Frequency of Children Experience Tropical Diseases during the Covid 19 Pandemic in Samarinda
Authors: Widiastuti Ida Ayu Kade Sri , Ruminem Ruminem , Sari Rita Puspa , Ermayani Made , Bahtiar Bahtiar
Published: November 2023

Warm temperatures, humidity, and high rainfall are factors in the high incidence of infectious diseases in the tropics. This condition is certainly risky for children's health. COVID-19 pandemic also adds to the risk of endangering the health of children in the golden period. In the golden period, infants and toddlers need adequate nutritional intake. Many factors hinder the provision of nutrition (ASI), one of which is the COVID 19 pandemic. Inadequate nutritional intake can lead to suboptimal growth and development of children, decreased immunity. The purpose of this study was to determine the effect of breastfeeding on nutritional status, and the frequency of children experiencing tropical diseases during the COVID 19 pandemic. Methods: Quantitative study with a categorical analytic research design. with a cross-sectional analytic approach. The sampling technique used a purposive sampling technique and the data collection tool was a questionnaire to measure the frequency of illness. Nutritional status measurement used anthropometric assessment. Conclusion: there is a significant relationship between breastfeeding and nutritional status and the frequency of illness in children. Recomedations:Therefore it is Important to campaign more intensively on the importance of breastfeeding for children's nutritional adequacy.
Communicative realization of basic human emotions in ukrainian and french languages
Authors:   Uman State Pedagogical University named after Pavlo Tychyna, Biletska I.O. , Laukhina I.S. ,   Uman State Pedagogical University named after Pavlo Tychyna, Paladieva A.F. ,   Uman State Pedagogical University named after Pavlo Tychyna
Published: November 2023

The monograph presents the results of the study of the concept as a holistic mental formation of cognitive science by members of the Laboratory of Linguistic Culture and Comparative Linguistics of Uman State Pedagogical University named after Pavlo Tychyna. Linguistic means of representing concepts expressing basic human emotions are characterized, and their comparative analysis in French and Ukrainian languages is carried out. Addressed to philologists, translators, teachers, bachelor's and master's degree holders of higher education institutions.
Concepts as a Means of Organizing Artistic Discourse
Authors: Vishniakova Aleksandra , Kuzioma Tatiana
Published: November 2023

The article deals with the peculiarities of modern foreign prose on the material of English writer Martin Amis’s novels. The basis of individual-author's picture representation of the world is the author's concepts system, which have common characteristics with the concepts of other authors, but differ in author's content, which makes it possible to talk about the uniqueness of the author's conceptosphere. Martin Amis in his work takes a passive creative position, striving to portray reality as it is. The author does not show ways out of the situation or options for solving problems, he takes the position of an outside observer, which is characteristic of most modern authors. The novels “Yellow Dog”, “The House of Meetings”, “The Zone of Interest” underwent the research as contain the relation concept as the main representative of individual thinking. Keywords: concept, relations, literature, novel, space category, Martin Amis
Cognitive and Emotional-Affective Disorders in Participants of Combat Actions with Traumatic Brain Injury (Review)
Authors: Saminin Ya.G. , Sokolova L.I.
Published: November 2023

Traumatic brain injury (TBI) is one of the main threats to the life and health of combatants. The modern paradigm of military affairs leads to a progressive increase in the prevalence of traumatic brain injury among combatants [1]. The symptoms that typically develop in this group of patients may include emotional lability, sleep and memory impairment, fatigue, anxiety, depression, and anger attacks. The origin of these symptoms is discussed: whether it is a manifestation of organic brain damage (diffuse and focal damage to different parts of the brain) or a functional disease (a disorder associated with exposure to a psycho-traumatic situation) [2]. Approaches to solving this issue included a detailed study of the pathogenetic mechanisms of TBI [3], evaluation of the effectiveness of various principles of treatment of post-traumatic encephalopathy [4], studies of the prevalence of depression [5], post-traumatic stress disorder (PTSD) [6], dementia [7], addictions to use of psychoactive substances [8] in traumatic brain injury. At this stage of research in the field of neurotraumatology, it is generally accepted that TBI or its consequences can manifest as psychiatric symptoms. However, we cannot deny the role of other causative factors in the pathogenesis of mental disorders in military personnel, such as heredity, environmental influences, unhealthy lifestyles, and concomitant somatic and neurological diseases. The prevalence of neuropsychological disorders in TBI varies significantly according to literature data, which can potentially be related to different methodologies for assessing psychological indicators and different approaches to the formation of studied groups of patients. The determination of the etiology of psychological symptoms in combatants with TBI is a topic of debate.»It requires further research and can potentially improve approaches to the treatment and rehabilitation of military personnel. Correction of the consequences of a mild TBI is one of the main tasks in the rehabilitation of combatants. Addressing cognitive, behavioral, and emotional disorders can significantly enhance the quality of life for individuals in this patient group.
Effectiveness of the Let’s Move It multilevel vocational school-based intervention on physical activity and sedentary behavior: A cluster randomized trial
Authors: Hankonen Nelli , Haukkala Ari , Palsola Minttu , Heino Matti Toivo Juhani , Sund Reijo , Tokola Kari , Absetz Pilvikki , Soares Vera Araujo , Sniehotta Falko , Borodulin Katja , Uutela Antti , Lintunen Taru , Vasankari Tommi
Published: November 2023

Background: Low levels of physical activity (PA), more prevalent among those with low education, require effective interventions. Fewer trials have tested interventions to decrease sedentary behaviour (SB). No school-based interventions have shown lasting effects on PA or sedentary behaviour in vocational schools. Purpose: To examine whether the Let’s Move It intervention has effects on behavioural and clinical outcomes among vocational students after two and 14 months.Methods: A cluster randomised trial in six school units in vocational education in Finland (N=1112) (mean age 18.5 years, range 15-46). The multi-component intervention targeted in-class activity opportunities (e.g., teacher-led activity breaks, equipment in classrooms), and students’ motivation and self-regulation (e.g., six group sessions, à 45-60 minutes, during the intensive intervention period of two months). Valid (≥4 days, ≥10 hours/d) accelerometer data were obtained from 741 students at baseline, 521 (70.3%) at 2 months, and 406 (54.8%) at 14 months.Results: No evidence of a significant intervention effect on the co-primary outcomes (moderate-to-vigorous PA, SB, breaks in SB) was found. Participants in the intervention arm reduced their total daily SB time by 32 minutes (95% CI -43.2 to -20.8) on weekdays, compared with the control arm’s reduction of 8.6 (95% CI -19.5 to 2.3) and engaged in more accelerometer-measured light PA during school time. Few differences were found in the secondary outcomes. Fidelity of intervention delivery was relatively good.Conclusions: This school-based intervention did not affect leisure-time activity. Despite a positive outcome on school-time light PA, more comprehensive or intensive environmental changes may be needed to meaningfully improve vocational students’ total activity.
ADHD Traits in the General Population and Their Association with Positive Aspects of ADHD
Authors: Schippers Lessa Madelief , Greven Corina , Hoogman Martine
Published: November 2023

Background: ADHD research has had a clear focus on symptoms, their negative consequences and the treatment of ADHD. However, previous qualitative research found that people with a diagnosis of ADHD also self-report to experience positive aspects related to their ADHD. This is one of the first quantitative studies to investigate multiple self-reported positive aspects in relation to ADHD traits in a general population sample. Therefore, our aim was to investigate the relationship between multiple self-reported positive aspects with ADHD traits in the general population using quantitative measures.Methods: Our sample consisted of individuals from the general population in the UK, aged 18-60, n=694. Next to assessing ADHD traits, we collected data on ten instruments investigating positive aspects that in qualitative research were reported to be related to Correlation analysis (primary) was supplemented by factor and network analyses analysis (exploratory). Results: We found positive correlations between ADHD traits and hyperfocus, sensory processing sensitivity, and cognitive flexibility. Conclusions: People with more ADHD traits score higher several positive aspects, for other strengths we were not able to show a positive correlation in this population-bases sample. Information on strengths may aid people with elevated ADHD traits cope with their condition, has potential to provide new angles for treatment.
The resolution of proactive interference in a novel visual working memory task: A behavioral and pupillometric study
Authors: Donenfeld Jamie , Blaser Erik , Kaldy Zsuzsa
Published: November 2023

Proactive interference (PI) occurs when previously learned information impairs memory for more recently learned information. Most PI studies have employed verbal stimuli, while the role of PI in visual working memory (VWM) has had relatively little attention. In the verbal domain, Johansson and colleagues (2018) found that pupil diameter – a real-time neurophysiological index of cognitive effort – reflects the accumulation and resolution of PI. Here we use a novel, naturalistic paradigm to test the behavioral and pupillary correlates of PI resolution for what-was-where item-location bindings in VWM. Importantly, in our paradigm, trials (PI versus no-PI condition) are mixed in a block, and participants are naive to the condition until they are tested. This design sidesteps concerns about differences in encoding strategies or generalized effort differences between conditions. Across three experiments (N = 122 total) we assessed PI’s effect on VWM and whether PI resolution during memory retrieval is associated with greater cognitive effort (as indexed by the phasic, task-evoked pupil response). We found strong support for PI’s detrimental effect on VWM (even with our spatially distributed stimuli), but no consistent link between interference resolution and effort during memory retrieval (this, even though the pupil was a reliable indicator that higher-performing individuals tried harder during memory encoding). We speculate that when explicit strategies are minimized, and PI resolution relies primarily on implicit processing, the effect may not be sufficient to trigger a robust pupillometric response.
Participatory Action Research in Social Sciences and Education
Authors: Puri Gobinda
Published: November 2023

Participatory action research, as other qualitative methods. like phenomenology, ethnography, narrative inquiry, autoethnography, and case studies, has emerged as a distinct field of study and established itself as a research design in the field of social sciences and education.  This methodological conceptual paper presents a review of participatory action research papers highlighting their meaning, purpose and use in research along with their definitions, the process of conducting research through participatory action research as a methodology, its guiding principles, strengths, weaknesses and challenges, applications, misconceptions and analysis of previous studies through participatory action research in various disciplines and contexts. This paper also highlights how participatory action research elevates the marginalized communities involved in the research process, solves their workplace problems and transforms their identities throughout the research by reviewing a few sample studies through participatory action research. The findings show that participatory action research has been immensely used in the social sciences and educational research for creating new knowledge as well as improving the existing situation. This paper might provide some significant insights into understanding and employing participatory action research to the teachers, teacher educators, and researchers who opt for using research as part of their academic degrees.
Performance Assessment of Kawasoti Water Supply and Sanitation Project, Nawalparasi, Nepal
Authors: Regmi Pradeep , Jnawali Shankar Mani
Published: November 2023

The Government of Nepal aimed to provide adequate basic supply of safe drinking water to all its citizens by 2023 (15thAdhar Patra, National Planning Commission). Although the national level of water supply and sanitation facility coverage is 88 and 98 percent respectively, only 25.4% of water supply projects are fully functional. The performance assessment of completed piped water supply scheme should to be assessed for the functionality and sustainability of the project. With an example of Kawasoti Small Town Water Supply Project (KSTWSP), performance of the service provider is assessed in terms of physical state, functionality, customer satisfaction, water resource management, financial management and human resource management. The major findings were that bacterial removal efficiency of slow sand filter is greater than 95 % and the turbidity from the outlet of slow sand filter was found to be less than 0.1 NTU. The study of financial data of Kawasoti WUSC shows that operating revenue is sufficient to cover the operating expenses of WUSC. The water demand for the year 2075 to 2086 were found to be (7.32, 7.58, 7.84, 8.12, 8.40, 8.69, 8.99, 9.31, 9.68, 10.07, 10.47, 10.89, 11.33 and 11.79) MLD respectively. The water production was taken as an average of 9.94 MLD. The analysis shows up to the year 2083, the system will be able to meet the water demand. So after 2083, the WUSC might need to make necessary arrangement for additional water sources to meet the water demand. Staff productivity index has been 3.70 from the year 2070 to 2075, which indicates efficient utilization of the staff. Thus the study concluded that the performance of Kawasoti WUSC is up to satisfactory level till this study year 2075.