bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors Contributing to Increased Patient Wait Times in Selected Wound Care Patients: A Retrospective Study
Authors: Aina Joan , Ade-Oshifogun Jochebed
Published: May 2018

Background: ‘Waiting’ can be frustrating for anyone especially when it comes to healthcare. The Institute of Medicine advocates changes to improve the quality of the health care delivery system in the United States.Purpose: The purpose of this retrospective study was to determine the factors contributing to increased patient wait times in selected wound care patients. The question guiding this project is-in selected wound care patients who received treatment between September1-December 31, 2013; are factors contributing to prolonged wait times related to treatment-related diagnosis, providers, and clinicians?Method: After institutional review board approval, retrospective charts review was conducted. 300 charts were randomly selected from the electronic health record (EHR) database at a local hospital wound care clinic. 120 charts met the inclusive criteria and were analyzed using ANOVA and SPSS version 22. The Deming cycle for quality improvement was adopted as the framework for practice review and changes.Result: Among all the factors examined, Treatment diagnosis accounted for 4% of the variance (p = 0.416); Providers 1% (p = 0.208); and Clinicians 8% (p = 0.195). Though clinicians had the highest variance, it was not a significant factor for patient wait times. The Deming cycle helps to prioritize and improve communication by creating a chart for effective patient flow through the clinic to reduce wait time.Conclusion: Correcting and improving wait times has the potential for increasing timely access and patient satisfaction. Clinicians and providers are not significant factors contributing to wait times. Wait time should be given priority and be regularly reviewed as part of the quality improvement plan within any organization.
Experimental Study on Methane Desorption from Lumpy Coal under the Action of Hydraulic and Thermal
Authors: Zhao Dong , Li Dayuan , Ma Yulin , Feng Zengchao , Zhao Yangsheng
Published: May 2018

Moisture and thermal are the key factors for influencing methane desorption during CBM exploitation. Using high pressure water injection technology into coalbed, new fractures and pathways are formed to methane transport. It is existed a phenomenon of water inhibiting gas flow. This study is focused on various water pressures impacted on gas adsorbed coal samples, then the desorption capacity could be revealed under different conditions. And the results are shown that methane desorption capacity was decreased with water pressure increased at room temperature and the downtrend would be steady until water pressure was large enough. Heating could promote gas desorption capacity effectively, with the increasing of water injection pressures, the promotion of thermal on desorption became more obvious. These results are expected to provide a clearer understanding of theoretical efficiency of heat water or steam injection into coalbed, they can provide some theoretical and experimental guidance on CBM production and methane control.
Graph Coloring: A Novel Heuristic Based on Trailing Path; Properties, Perspective and Applications in Structured Networks
Authors: Bandyopadhyay Abhirup , Dhar Amit Kumar , Basu Sankar
Published: May 2018

Graph coloring is a manifestation of graph partitioning, wherein, a graph is partitioned based on the adjacency of its elements. Partitioning serves potentially as a compartmentalization for any structural problem. Vertex coloring is the heart of the problem which is to find the chromatic number of a graph. The fact that there is no general efficient solution to this problem that may work unequivocally for all graphs opens up the realistic scope for combinatorial optimization algorithms to be invoked. The algorithmic complexity of graph coloring is non-deterministic in polynomial time (NP) and hard. To the best of our knowledge, there is no algorithm as yet that procures an exact solution of the chromatic number comprehensively for any and all graphs within the polynomial (P) time domain. However, several heuristics as well as some approximation algorithms have been attempted to obtain an approximate solution for the same. Here, we present a novel heuristic, namely, the 'trailing path', which returns an approximate solution of the chromatic number within polynomial time, and, with a better accuracy than most existing algorithms. The ‘trailing path’ algorithm is effectively a subtle combination of the search patterns of two existing heuristics (DSATUR and Largest First), and, operates along a trailing path of consecutively connected nodes (and thereby effectively maps to the problem of finding spanning tree(s) of the graph) during the entire course of coloring, where essentially lies both the novelty and the apt of the current approach. The study also suggests that the judicious implementation of randomness is one of the keys towards rendering an improved accuracy in such combinatorial optimization algorithms. Apart from the algorithmic attributes, essential properties of graph partitioning in random and different structured networks have also been surveyed, followed by a comparative study. The study reveals the remarkable stability and absorptive property of chromatic number across a wide array of graphs. Finally, a case study is presented to demonstrate the potential use of graph coloring in protein design – yet another hard problem in structural and evolutionary biology.
Unanswered Questions Regarding Sex and BMP/TGF-β Signaling
Authors: Shah Tapan A. , Rogers Melissa B.
Published: May 2018

Crosstalk between the BMP and TGF-β signaling pathways regulates many complex developmental processes from the earliest stages of embryogenesis throughout adult life. In many situations, the two signaling pathways act reciprocally. For example, TGF-β signaling is generally pro-fibrotic whereas BMP signaling is anti-fibrotic and pro-calcific. Sex-specific differences occur in many diseases including cardiovascular pathologies. Differing ratios of fibrosis and calcification in stenotic valves suggests that BMP/TGF-β signaling may vary in men and women. In this review, we focus on the current understanding of the interplay between sex and BMP/TGF-β signaling and pose several unanswered questions.
Condições de saúde bucal de usuários de crack:um problema de saúde pública
Authors: Barbosa Danilo Vieira , Souto-Nóbrega Winícius , Souto-Nóbrega Waleska Fernanda
Published: May 2018

Introdução: O efeito imediato do crack é uma euforia intensa, entretanto, quando usado frequentemente, pode ocasionar paradas cardíacas, hemorragia pulmonar, pneumonia, infarto de músculos e da pele, úlceras no trato gastrointestinal, não obstante lesões bucais e de orofaringe. Logo, o cirurgião-dentista deve estar alerta para alguns achados orais que possam estar relacionados ao consumo de drogas ilícitas, pois, geralmente, são estes profissionais os primeiros a terem a oportunidade de diagnosticar alterações bucais devido ao uso de álcool, cigarro e drogas ilícitas. Objetivo: O presente estudo tem por objetivo realizar uma revisão da literatura a respeito das condições de saúde bucal dos usuários de crack. Metodologia: Foram utilizados 15 artigos científicos de pesquisa original, os quais foram pesquisados nas bases de dado Scielo, Medline, Scopus e Pubmed através dos descritores "usuário de crack", "saúde bucal" e "drogas ilícitas" nos idiomas português e inglês. Conclusões: Ainda são poucos os estudos que tratam desta temática, sendo necessário um maior número de pesquisas que possam contribuir para a definição de estratégias de atenção à saúde do dependente de crack.Descritores: Cocaína Crack; Odontólogo; Drogas Ilícitas; Saúde Bucal.
Eficácia do controle de biofilme dental em pacientes portadores de transtorno psiquiátrico
Authors: Takahashi Karine , Nunes Ariane Santana , Santos Eberti Cristovão , Santos Luis Henrique Pereira dos , Araujo Heitor Ceolin , Prado Rosana Leal do
Published: May 2018

Introdução: A desorganização da placa bacteriana dentária através da higienização mecânica é o meio mais eficaz para evitar processo inflamatório bucal. A negligência da remoção mecânica do biofilme acarreta gengivite com possível evolução a periodontite. A Doença Periodontal é a condição bucal mais preocupante entre os pacientes com distúrbios mentais, apesar de prazeroso cuidar do familiar psicopatológico há uma sobrecarga aos cuidadores, assim as alterações psiquiátricas devem ser identificadas o quanto antes visando manutenção da higienização pessoal e bucal. Objetivo: Esta pesquisa teve como objetivo avaliar as condições bucais periodontais e de higiene oral de pacientes frequentadores de instituição psiquiátrica tanto na forma de internação (hospital Especialidade – HE) quanto na presença diária (Hospital Dia – HD), correlacionando as condições bucais encontradas e grau de higiene bucal. Material e Método: Para tanto, avaliou-se pacientes do hospital psiquiátrico Allan Kardec localizado na região de Presidente Prudente – SP. Grau de higiene oral deu-se pela coloração da placa por pastilha evidenciadora e aplicação do Índice Higiene Oral Simplificado (IHOS). A seguir, realizou-se avaliação das condições periodontais pelo Índice Periodontal Comunitário. Resultados: Uma amostra de 47 pacientes participou do estudo, sendo 19 em sistema de HD e 28 do HE, tanto os em sistema HD e HE, na variável IHOS, observou-se mais prevalente score 3, sendo 42,11% para HD e 35,71% para HE, na variável Profundidade de Sondagem mais prevalente foi de 4 a 5 mm tanto para HD quanto para HE sendo 35,71%, e 47,37% respectivamente. Conclusão: não foi verificada diferença estatisticamente significante entre os grupos avaliados (p>0,005).Descritores: Doenças Periodontais; Transtornos Mentais; Biofilmes; Placa Dentária.
Assessing water quality for urban tributaries of the Three Gorges Reservoir, China
Authors: Zhu Senlin , Mostafaei Abazar , Luo Wenguang , Jia Benyou , Dai Jiangyu
Published: May 2018

Water quality assessment is essential for water resources management. This paper presents a comprehensive evaluation of water quality conditions in three urban tributaries of the Three Gorges Reservoir, China. The Canadian Council of Ministers of the Environment Water Quality Index (CCME-WQI) and Nemerow Pollution Index (NPI) approach were used in this study. Generally, the assessment results of the NPI approach are consistent with that of the CCME-WQI approach. However, the NPI method overemphasized the influence of the most serious pollutant factor, and thus this method should be used with caution for water resources managers. The CCME-WQI values indicated that the water quality conditions in the Wubu River were quite good during the period 2013–2015. Water quality conditions in the upstream sections of Yipin and Huaxi River are good. However, when the river drains through urban areas, water quality conditions greatly deteriorate due to the excessive release of household and municipal sewage, and industrial wastewater, especially for Huaxi River. Thus, waste water management becomes more and more imperative in urban regions of China. Meanwhile, assessment results indicate that the CCME-WQI approach can provide a reference for decision-makers on water resources management.
Anti-TNF Biosimilars in Inflammatory Bowel Disease: Searching the Proper Patient's Profile
Authors: Danese Silvio , Fiorino Gionata
Published: May 2018

Biosimilars of infliximab (CT-P13) are currently approved and available for the
same indications as for the originator. Some concerns about safety and immunogenicity have
risen in the past because of lack of data in IBD. Since 2015, several cohort studies have been
conducted in IBD showing that CT-P13 has comparable safety and efficacy profile to the
originator, both in adult and pediatric population, either in naïve patients or even in those who
switched from the originator to CT-P13. This review aims to analyze the current literature
data in order to define a clear patient profile, to identify those IBD patients who would benefit
the most from the use of CT-P13.
FDG PET/CT Imaging in Diabetic Patients - A Special Emphasis on Imaging of Infection
Authors: Keidar Zohar
Published: May 2018

Nuclear Medicine (NM) imaging plays a major role in the assessment of infection and inflammation.
Tracers, including single photon emitting radionuclides for Single Photon Emission Tomography (SPECT) and
agents for positron emission tomography (PET), reflect primarily tissue and cellular function or metabolism. In
the specific clinical setting of a patient with suspected infectious or inflammatory process, planar scintigraphy,
SPECT or PET procedures are used to support a clinically suspected diagnosis. Integrating metabolic and anatomic
information using a single SPECT/CT or PET/CT technique has substantially improved the diagnostic accuracy
of these imaging tests and advanced the NM technology to be a significant and important tool in the field of
infection and inflammation. Diabetes, one of the most prevalent diseases, has a direct relationship with the development
of various infection related condition. Due to alterations in different metabolic pathways, imaging of the
diabetic patient may be subject to specific pitfalls and obstacles which should be taken into consideration. This
review aimed at describing the impact of diabetes and hyperglycemia on NM imaging, with an emphasis on FDGPET/
CT, in specific infectious conditions related to diabetes.
A Review of Landfill Gas Generation and Utilisation in Africa
Authors: Njoku Prince O. , Odiyo John O. , Durowoju Olatunde S. , Edokpayi Joshua N.
Published: May 2018

This review evaluates the current Landfill Gas (LFG) utilisation technology across Africa and gives general overview on the global context. With the increase in global Municipal Solid Waste (MSW), the world has embraced landfilling to be its major way of MSW management. About 85% of the world’s MSW is deposited in landfills. This has brought increased concerns of gases emitted from landfill sites. These gases have contributed enormously to the global anthropogenic Greenhouse Gas (GHG) emission which are detrimental to the world’s environmental media. Although significant progress has been made on the utilization of landfill gases but this is limited to some developed countries, while in Africa, there has been limited strategies and control of LFG emissions. This review spotted several reasons that could have influenced the low development of LFG utilisation in Africa as ranging from lack of skilled expertise, inadequate knowledge of the technology involved, lack of political will, inadequate funding for LFG utilization projects and monopoly of the power sector among others. It is recommended that urgent attention should be given to LFG utilisation as it can aid in acquiring carbon credits, reduction in obnoxious smell and odours, and provide the much-needed energy which is crippling the economy in Africa as well as reducing the consequences associated with the release of greenhouse gases to the environment.
Usability and Acceptability of a Home Blood Pressure Telemonitoring Device Among Community-Dwelling Senior Citizens With Hypertension: Qualitative Study (Preprint)
Authors: Albrecht Lauren , Wood Peter W , Fradette Miriam , McAlister Finlay A. , Rabi Doreen , Boulanger Pierre , Padwal Raj
Published: May 2018

BACKGROUND

Hypertension is a major cause of cardiovascular disease in older individuals. To ensure that blood pressure (BP) levels are within the optimal range, accurate BP monitoring is required. Contemporary hypertension clinical practice guidelines strongly endorse the use of home BP measurement as a preferred method of BP monitoring for individuals with hypertension. The benefits of home BP monitoring may be optimized when measurements are telemonitored to care providers; however, this may be challenging for older individuals with less technological capabilities.

OBJECTIVE

The objective of this qualitative study was to examine the usability and acceptability of a home BP telemonitoring device among senior citizens.

METHODS

We conducted a qualitative descriptive study. Following a 1-week period of device use, individual, semistructured interviews were conducted. Interview audio recordings were anonymized, de-identified, and transcribed verbatim. We performed thematic analysis on interview transcripts.

RESULTS

Seven senior citizens participated in the usability testing of the home BP telemonitoring device. Participants comprised females (n=4) and males (n=3) with a mean age of 86 years (range, 70-95 years). Overall, eight main themes were identified from the interviews: (1) positive features of the device; (2) difficulties or problems with the device; (3) device was simple to use; (4) comments about wireless capability and components; (5) would recommend device to someone else; (6) would use device in future; (7) suggestions for improving the device; and (8) assistance to use device. Additional subthemes were also identified.

CONCLUSIONS

Overall, the home BP telemonitoring device had very good usability and acceptability among community-dwelling senior citizens with hypertension. To enhance its long-term use, few improvements were noted that may mitigate some of the relatively minor challenges encountered by the target population.
Development of a Smartphone App for Informal Carers of People With Cancer: Processes and Learnings (Preprint)
Authors: Heynsbergh Natalie , Heckel Leila , Botti Mari , O Eric (Seung Chul) , Livingston Patricia M
Published: May 2018

BACKGROUND

There are few support systems available to informal carers who provide care to cancer patients. Smartphone apps have the capacity to reach large audiences and can provide information and support at a time convenient to carers.

OBJECTIVE

The aim of this study was to design a smartphone app prototype for carers of adults with cancer.

METHODS

A multiple-method design was used to develop a smartphone app. Current and past carers of people with any type of cancer were recruited from a public hospital, a private hospital, and a carer organization, who participated in either a focus group or phone interview. Carers answered questions about items to include in an app to address supportive care needs identified. Using carers’ feedback, a smartphone app was designed and tested. Beta testing was conducted using a convenience sample of participants who completed scenarios to inform the app’s design, functionality, and usability. Scenarios were timed and marked as complete or incomplete. Participants completed a questionnaire about the usability of the app. Beta testing occurred in 2 stages—a paper-based version of the app and an app-based test using the participants’ preferred device. Alpha testing was completed internally to ensure the functionality of the app. Data were collected between May 2016 and August 2017.

RESULTS

A total of 33 carers participated in phone interviews and 12 in focus groups; their average age was 55 (SD 14) years, and 60% (27/45) were female. The majority of carers (76%, 25/33) had a positive attitude toward using smartphone apps. Carers noted that smartphone technology might improve their ability to seek information and support in managing their own health as well as the care needs of the person with cancer. Carers requested a variety of information and resources to be included in the app. Paper-based testing included the following: participants (N=10) were aged above 30 years (30%, 3/10), 30 to 49 years (30%, 3/10), and 50 years or above (40%, 4/10), and 60% (6/10) were male. Participants found the app user-friendly and pleasing in appearance. App-based testing included the following: participants (N=10) were aged above 30 years (20%, 2/10), 30 to 49 years (30%, 3/10), and 50 years or above (50%, 5/10), and 50% (5/10) were male. Participants reported the app to be user-friendly and easy to navigate. The majority (60%, 6/10) of participants were unable to create a shortcut icon to add the app to the home screen of their phone.

CONCLUSIONS

Carers highlighted the needed information and support to assist them during the caring period; they also reported having a positive attitude toward smartphone apps. The Carer Guide App is currently undergoing a pilot study to further test usability among carers of people with 1 cancer type.
National Survey of Morbidity and Risk Factors (EMENO): Protocol for a Health Examination Survey Representative of the Adult Greek Population (Preprint)
Authors: Touloumi Giota , Karakatsani Anna , Karakosta Argiro , Sofianopoulou Eleni , Koustenis Panagiotis , Gavana Magda , Alamanos Yannis , Kantzanou Maria , Konstantakopoulos George , Chryssochoou Xenia , Benos Alexis , Vantarakis Apostolos , Hadjichristodoulou Christos , Chlouverakis Gregory , Trypsianis Gregory , Voulgari Paraskevi V , Makrilakis Konstantinos , Liatis Stavros , Stergiou George ,   EMENO Study Group
Published: May 2018

BACKGROUND

Main causes of death in Greece are cardiovascular diseases (CVDs), malignant neoplasms, respiratory diseases, and road traffic crashes. To assess the population health status, monitor health systems, and adjust policies, national population-based health surveys are recommended. The previous health surveys that were conducted in Greece were restricted to specific regions or high-risk groups.

OBJECTIVE

This paper presents the design and methods of the Greek Health Examination Survey EMENO (National Survey of Morbidity and Risk Factors). The primary objectives are to describe morbidity (focusing on CVD, respiratory diseases, and diabetes), related risk factors, as well as health care and preventive measures utility patterns in a random sample of adults living in Greece.

METHODS

The sample was selected by applying multistage stratified random sampling on 2011 Census. Trained interviewers and physicians made home visits. Standardized questionnaires were administered; physical examination, anthropometric and blood pressure measurements, and spirometry were performed. Blood samples were collected for lipid profile, glucose, glycated hemoglobin, and transaminases measurements. The survey was conducted from May 2013 until June 2016.

RESULTS

In total, 6006 individuals were recruited (response rate 72%). Of these, 4827 participated in at least one physical examination, 4446 had blood tests, and 3622 spirometry, whereas 3580 provided consent for using stored samples for future research (3528 including DNA studies). Statistical analysis has started, and first results are expected to be submitted for publication by the end of 2018.

CONCLUSIONS

EMENO comprises a unique health data resource and a bio-resource in a Mediterranean population. Its results will provide valid estimates of morbidity and risk factors’ prevalence (overall and in specific subdomains) and health care and preventive measures usage in Greece, necessary for an evidence-based strategy planning of health policies and preventive activities.

INTERNATIONAL REGISTERED REPOR

DERR1-10.2196/10997
The Advantages and Disadvantages of Online and Blended Therapy: Survey Study Amongst Licensed Psychotherapists in Austria (Preprint)
Authors: Schuster Raphael , Pokorny Raffaela , Berger Thomas , Topooco Naira , Laireiter Anton-Rupert
Published: May 2018

BACKGROUND

Web-based and blended (face-to-face plus Web-based) interventions for mental health disorders are gaining significance. However, many licensed psychotherapists still have guarded attitudes toward computer-assisted therapy, hindering dissemination efforts.

OBJECTIVE

The objective of this study was to provide a therapist-oriented evaluation of Web-based and blended therapies and identify commonalities and differences in attitudes toward both formats. Furthermore, it aimed to test the impact of an information clip on expressed attitudes.

METHODS

In total, 95 Austrian psychotherapists were contacted and surveyed via their listed occupational email address. An 8-minute information video was shown to half of the therapists before 19 advantages and 13 disadvantages had to be rated on a 6-point Likert scale.

RESULTS

The sample resembled all assessed properties of Austrian psychotherapists (age, theoretical orientation, and region). Therapists did not hold a uniform overall preference. Instead, perceived advantages of both interventions were rated as neutral (t94=1.89, P=.06; d=0.11), whereas Web-based interventions were associated with more disadvantages and risks (t94=9.86, P<.001; d=0.81). The information clip did not excerpt any detectable effect on therapists’ attitudes (r95=−.109, P=.30). The application of modern technologies in the own therapeutic practice and cognitive behavioral orientation were positively related to the given ratings.

CONCLUSIONS

This study is the first to directly compare therapists’ attitudes toward Web-based and blended therapies. Positive attitudes play a pivotal role in the dissemination of new technologies, but unexperienced therapists seem to lack knowledge on how to benefit from technology-aided treatments. To speed up implementation, these aspects need to be addressed in the development of new interventions. Furthermore, the preference of blended treatments over Web-based interventions seems to relate to avoidance of risks. Although this study is likely to represent therapists’ attitudes in countries with less advanced electronic health services, therapists’ attitudes in more advanced countries might present differently.
Applying an Author-Weighted Scheme to Identify the Most Influential Countries in Research Achievements on Skin Cancer: Observational Study (Preprint)
Authors: Chien Tsair-Wei , Wang Hsien-Yi , Lai Feng-Jie
Published: May 2018

BACKGROUND

Skin cancers are caused by the development of abnormal cells that can invade or spread to other parts of the body. The countries whose authors contribute the most amount of articles on skin cancer to academia is still unknown.

OBJECTIVE

The objectives of this study are to apply an author-weighted scheme (AWS) to quantify the credits for coauthors on an article byline and allocate the author weights to the country-level credits in articles.

METHODS

On July 20, 2019, we obtained 16,804 abstracts published since 1938, based on a keyword search of “skin cancer” in PubMed. The author names, countries/areas, and journals were recorded. International author collaborations on skin cancer were analyzed based on country-level credits in articles. We aimed to do the following: (1) present country distribution for the first authors and the most popular journals, (2) show choropleth maps to highlight the most influential countries, and (3) draw scatter plots based on the Kano model to characterize the features of country-level research achievements. We programmed Excel Visual Basic for Applications (Microsoft Corp) routines to extract data from PubMed. Google Maps was used to display graphical representations.

RESULTS

Our results suggest that researchers in the United States have published most frequently, accounting for 30.37% (5103), while Germany accounts for 7.34% (1234), followed by Australia (997, 5.93%). The top three continents for the proportion of published articles are North America, Europe, and Asia, accounting for 32.29%, 31.71%, and 10.41%, respectively.

CONCLUSIONS

This study offers an objective picture of the representativeness and evolution of international research on the topic of skin cancer. The research approaches used here have the potential to be applied to other areas besides skin cancer.
Walking With a Robotic Exoskeleton Does Not Mimic Natural Gait: A Within-Subjects Study (Preprint)
Authors: Swank Chad , Wang-Price Sharon , Gao Fan , Almutairi Sattam
Published: May 2018

BACKGROUND

Robotic exoskeleton devices enable individuals with lower extremity weakness to stand up and walk over ground with full weight-bearing and reciprocal gait. Limited information is available on how a robotic exoskeleton affects gait characteristics.

OBJECTIVE

The purpose of this study was to examine whether wearing a robotic exoskeleton affects temporospatial parameters, kinematics, and muscle activity during gait.

METHODS

The study was completed by 15 healthy adults (mean age 26.2 [SD 8.3] years; 6 males, 9 females). Each participant performed walking under 2 conditions: with and without wearing a robotic exoskeleton (EKSO). A 10-camera motion analysis system synchronized with 6 force plates and a surface electromyography (EMG) system captured temporospatial and kinematic gait parameters and lower extremity muscle activity. For each condition, data for 5 walking trials were collected and included for analysis.

RESULTS

Differences were observed between the 2 conditions in temporospatial gait parameters of speed, stride length, and double-limb support time. When wearing EKSO, hip and ankle range of motion (ROM) were reduced and knee ROM increased during the stance phase. However, during the swing phase, knee and ankle ROM were reduced when wearing the exoskeleton bionic suit. When wearing EKSO, EMG activity decreased bilaterally in the stance phase for all muscle groups of the lower extremities and in the swing phase for the distal muscle groups (tibialis anterior and soleus) as well as the left medial hamstrings.

CONCLUSIONS

Wearing EKSO altered temporospatial gait parameters, lower extremity kinematics, and muscle activity during gait in healthy adults. EKSO appears to promote a type of gait that is disparate from normal gait in first-time users. More research is needed to determine the impact on gait training with EKSO in people with gait impairments.
Evaluation of Flood Risk Reduction Project at Tenggang River, Semarang City, Central Java Province, Indonesia
Authors: Udom Nuon , Istiarto Istiarto , Rahardjo Adam Pamudji
Published: May 2018

Evaluation of flood risk reduction at Tenggang River is needed to reduce the urban and coastal flood from high-intensity rainfall and sea level rise. This paper mainly discusses rainfall frequency analysis, simulation of hydraulic structure performed by HEC-RAS 5.0.3, and the proposed alternative flood mitigation for 25-year flood return period. Hydrology and hydraulic was analyzed to investigate the flooding risk. The result of simulation illustrated the improvement channel condition by normalization the riverbed and the increase of levee to solve flood inundation at Tenggang River using the designated flood return period (25 years of return period, Q25 = 119 m3/s). The result of simulation showed that the hydrologic-hydraulic modeling is acceptable compared to the report from the office of public work in Semarang City.
Pengantar Redaksi
Authors: Sosiologi Jurnal Pemikiran
Published: May 2018

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Cost of treating peripheral neuropathic pain with pregabalin or gabapentin at therapeutic doses in routine practice
Authors: Sicras-Mainar Antoni , Rejas-Gutiérrez Javier , Perez-Paramo Maria , Navarro-Artieda Ruth
Published: May 2018

Aim:
To analyze the cost of peripheral neuropathic pain (PNP) treatment with pregabalin or gabapentin at therapeutic doses in routine clinical practice.
Methods:
Analysis of a retrospective, observational study of electronic medical records of patients treated for PNP with therapeutic doses of pregabalin or gabapentin, with 2 years’ follow-up, considering PNP type, comorbidities, concomitant analgesia and resource use.
Results:
The weighted total average cost/patient was lower for pregabalin than gabapentin (€2464 [2197–2730] vs €3142 [2670–3614]; p = 0.014) due to significantly lower both healthcare and non-healthcare costs. This is explained by a significantly lower use of concomitant analgesia, fewer primary care visits and fewer days of sick leave.
Conclusion:
At therapeutic doses, pregabalin was found to have lower healthcare and non-healthcare costs than gabapentin in routine practice.
Formarse para transformar valoración del proceso formativo de estudiantes de la Universidad Veracruzana Intercultural (UVI)
Authors: Jiménez Moyo Cuauhtémoc
Published: May 2018

El presente trabajo tiene como objetivo valorar el proceso formativo de estudiantes de la UVI Grandes Montañas, a través del análisis crítico de sus trabajos de Investigación Vinculada para la Gestión (IVG), realizados en un periodo que oscila entre un año, para algunos casos, o hasta dos años y medio, para otros. Se trata de una evaluación realizada a diez estudiantes de la generación 2012-2016, que cursaron la experiencia educativa “Experiencia Recepcional” en el periodo febrero-agosto de 2016. Los resultados preliminares de la investigación muestran que la propuesta formativa de la UVI, se concentra en la búsqueda por la pertinencia cultural y lingüística, así como en el fortalecimiento y dinamización de las culturas indígenas de nuestro Estado.
Expresiones del Arte Totonaco Una experiencia de gestión del aprendizaje
Authors: Cruz González Carlos Alberto
Published: May 2018

En este artículo se describe el proceso de intervención educativa que se desarrolló durante la experiencia educativa de Expresiones del Arte Totonaco, que tiene como objetivo, generar y desarrollar competencias interculturales en los estudiantes de la Universidad Veracruzana (UV), enfatizando en el proceso de aprendizaje en la construcción e interiorización de dichas competencias, mediante un acercamiento a la diversidad cultural de Totonacapan, reconociendo la otredad generada en el contexto intercultural. Para ello, la experiencia educativa se enfocó en una metodología de investigación-acción que permitió desarrollar una estrategia de intervención educativa que se basa en la generación de aprendizaje mediante el diálogo. La experiencia educativa generó una resignificación relevante en cada uno de los diferentes perfiles formativos de los jóvenes universitarios y los resultados del aprendizaje obtenido permiten reconocer, reflexionar y analizar su concepto de identidad, interculturalidad, relaciones interculturales y reconocimiento de la diversidad del mundo totonaca. 
ACURÁCIA DA CITOLOGIA VAGINAL E COLPOSCOPIA PARA DIAGNÓSTICO DE NEOPLASIA INTRAEPITELIAL CERVICAL NO CICAN-BAHIA
Authors: Da Silva Allan Nogueira , Pimentel Kleber , Martins Maria Tereza Silveira , Da Silva Carlos Alberto Lima , Lopes Antônio Carlos Vieira , Torrales Maria Betânia
Published: May 2018

O rastreamento do câncer do colo uterino é realizado por meio da citologia cervical e colposcopia. O objetivo deste estudo foi avaliar a acurácia da citologia cervical e da colposcopia para o diagnóstico de neoplasia intraepitelial cervical no do Centro Estadual de Oncologia. Para tanto, utilizou-se os dados das citologias de 351 pacientes e de 378 colposcopias que também realizaram biópsias de lesões suspeitas. Foram estimadas as medidas de acurácia das citologias e das colposcopias. Os valores da sensibilidade e especificidade para citologia foram de 85,04% (Intervalo de Confiança 95% 80,34 – 89,01), 40% (Intervalo de confiança 95% 28,47 – 52,41), respectivamente; e, para colposcopia, de 97,73% (Intervalo de confiança 95% 95,37 – 99,08) e 15,79% (Intervalo de confiança 95% 8,43 – 25,96), respectivamente. O valor da Razão de Probabilidade positiva da citologia foi de 1,42 (Intervalo de confiança 95%, 1,16 – 1,72) e da Razão de Probabilidade negativa foi de 0,37 (Intervalo de confiança 95%, 0,25 – 0,56). Já para colposcopia, o valor da Razão de Probabilidade positiva foi de 1,16 (Intervalo de confiança 95%, 1,05 – 1,28); e, a Razão de Probabilidade negativa de 0,14 (Intervalo de confiança 95%, 0,06 – 0,36). Assim, sugere-se que a capacidade da citologia e colposcopia de modificar a probabilidade pós-teste de doença no Centro Estadual de Oncologia é pequena, em virtude do baixo valor das Razões de Probabilidade positiva.

Palavras-chave: Citologia. Exame de Papanicolaou. Neoplasia intraepitelial cervical. Colposcopia, prevenção e controle.
FORMAÇÃO DE EDUCADORES PARA PROMOÇÃO DA SAÚDE ÚNICA EM DISTRITO SANITÁRIO DE SALVADOR: ESTUDO PILOTO
Authors: Seixas Mone Martins , Nery Gabriela , De Souza Elmara Pereira , Franke Carlos Roberto , Bavia Maria Emília , Melo Stella Maria Barrouin
Published: May 2018

No Brasil, um país de clima tropical e grande diversidade sociocultural, as doenças infectocontagiosas representam um desafio, e a educação em saúde pode ter um poder significativo no combate às doenças zoonóticas. O objetivo deste artigo é identificar e classificar informações sobre agravos zoonóticos, para aplicá-las sob a forma de curso para professores da rede pública. Foi realizada uma pesquisa-intervenção no Distrito Sanitário Cabula/Beirú, em Salvador, Bahia, Brasil. Paralelamente, foram avaliados conhecimentos desses professores sobre temas relacionados à Saúde Única para direcionar a prática educativa para a prevenção de zoonoses e promoção da saúde humana e animal. Os dados obtidos no Sistema Nacional de Agravos de Notificação subsidiaram os questionários aplicados a 32 educadores e 324 educandos do ensino fundamental para a construção do Curso de Formação de Multiplicadores, intervenção educativa online, realizada por meio da Plataforma Moodle da Universidade Federal da Bahia. Foram realizados pré e pós-testes, avaliados pelo Método Soma. Em ambos os grupos, educadores e educandos, os pré-testes evidenciaram desconhecimento, tanto sobre a ocorrência das doenças quanto sobre as medidas preventivas. Esses dados nortearam a prática educativa, que resultou em 100% de eficiência na aprendizagem da maioria dos tópicos e multiplicação nas classes, conforme resultados evidenciados no pós-teste. O curso despertou interesse na comunidade escolar, com 63,3% de preenchimento das vagas por professores e 23,3% por outros interessados, restando 13,4%. Entretanto o índice de evasão foi de 60%. Concluiu-se que a educação online é efetiva em formar educadores multiplicadores, porém o incentivo para a participação dos profissionais requer diálogo entre gestores das áreas de saúde e educação.

Palavras-chave: Educação em saúde. Educação a distância. Bem-estar animal.
PROGRAMA PET-SAÚDE REDE CEGONHA: RELATO DE EXPERIÊNCIA
Authors: Fontenele Susan Karollyne , Barros Leidiane Pio , Lopes Hianna Rayza Ferreira , Bittencourt Anna Luiza Alves , Batista Daniel Nascimento , Magalhães Alessandra Tanuri
Published: May 2018

O Programa Rede Cegonha visa à ampliação do acesso e melhoria da qualidade da atenção pré-natal, da assistência ao parto e puerpério e da assistência à criança até os dois anos de vida. O estudo objetivou apontar as abordagens práticas e as contribuições do Programa de Educação pelo Trabalho para Saúde Rede Cegonha (PET-Cegonha), em uma Unidade Básica de Saúde no município de Parnaíba, Piauí, Brasil. Trata-se de um relato de experiência em que foram realizadas rodas de conversa e dinâmicas como ferramentas para comunicação e integração do grupo, além de atividades entre os acadêmicos e a equipe da Unidade Básica de Saúde. Os resultados mostram como foi realizado o processo de territorialização; as ações foram construídas em conjunto com os preceptores, acadêmicos, tutores e profissionais e divididas em 4 eixos: tecnologias de cuidado, educação permanente, gestão do trabalho e participação popular. A Unidade Básica de Saúde apresentou grandes mudanças e avanços no que diz respeito à organização, melhor cobertura e fluxo dos atendimentos, além de obter maior participação popular nas atividades coletivas e adesão das gestantes ao pré-natal. Concluiu-se que a Rede Cegonha pode ser considerada um laço materno-infantil entre a política e a saúde da mulher e não se caracteriza como programa, mas sim como um conjunto de ações que visam à melhoria da atenção dirigida às mulheres e às crianças.

Palavras-chave: Programa de Educação pelo Trabalho para a Saúde. Saúde pública. Saúde.
ANÁLISE COMPARATIVA DE AGENTES MICROBIOLÓGICOS DO COLO UTERINO EM REGIÕES DO RIO GRANDE DO SUL
Authors: Calil Luciane Noal , Backes Luana Taís Hartmann , Koppe Marina , Manfredini Vanusa
Published: May 2018

O diagnóstico citológico cérvico-vaginal tem a capacidade de identificar alterações celulares, provocadas por agente microbiológico, que podem causar processos inflamatórios e lesões na cérvice uterina. O objetivo deste estudo foi comparar a frequência de agentes infecciosos que acometem o colo uterino na população de duas regiões distintas do estado do Rio Grande do Sul por meio de um estudo quantitativo, comparativo e retrospectivo, utilizando resultados oriundos de 9782 laudos citopatológicos cervicovaginais entre julho e dezembro de 2012. Na região Norte, com os dados coletados de 6499 exames, verificou-se o predomínio da flora lactobacilar em 60,8% dos exames, seguida de flora mista em 11,9%, Gardnerella vaginalis em 10,4%, Candida sp em 1,3% e Trichomonas vaginalis em 0,38%. Na região Noroeste, dos 3283 resultados de exames analisados, 57,2% das amostras continham Lactobacilos, 7,2% Gardnerella vaginalis em 18,2%, flora cocóide em 16,2%, flora mista em 4,8%, Candida sp em 2,9% e Trichomonas vaginalis em 0,58%. Verificou-se uma diferença estatisticamente significativa entre as médias de idade das pacientes portadoras de Cândida sp, com maior predominância na região norte. A presença de flora mista também foi significativamente maior nessa região. Assim, concluiu-se que a realização de pesquisas adicionais pode contribuir para esclarecer os fatores causais e se o uso de hormônios poderia estar envolvido no desenvolvimento de quadros inflamatórios nessa região. Programas de rastreamento, por meio de exame citológico do colo uterino, têm sido estratégias públicas efetivas para a detecção de inflamações no intuito de estimular a adoção de protocolos de prevenção e o autocuidado.

Palavras-chave: Patologia. Microbiologia. Prevenção. Controle.
CONHECIMENTO SOBRE A LUTA ANTIMANICOMIAL NO INTERIOR DE MATO GROSSO
Authors: Fonseca Wliane Nunes Silva , Lemes Alisséia Guimarães , Cardoso Tayane Próspero , Araújo Monaquesia Pereira , Basso Tayla Quéren dos Santos , Moura Adaene Alves Machado de , Carrijo Marcos Vítor Naves , Rocha Elias Marcelino da , Nascimento Vagner Ferreira do , Volpato Rosa Jacinto
Published: May 2018

Em 1978, o movimento pela Luta Antimanicomial surgiu para transformar a relação da sociedade e do Estado com a loucura, buscando os direitos das pessoas com sofrimento mental, que nos anos 80, o cenário era de total desassistência. Objetivou-se descrever o conhecimento da comunidade sobre a Luta Antimanicomial. Trata-se de uma pesquisa exploratória, com abordagem quantitativa, realizada com amostragem de conveniência dos participantes da ação realizada no dia 18 de maio de 2015, em alusão a Luta Antimanicomial em Barra do Garças, Mato Grosso. Para coleta de dados, foi utilizado um questionário semiestruturado. As análises foram realizadas no programa Epi Info versão 3.5.2. Os 223 participantes apresentaram idade de 18 a 89 anos, 67% sexo  masculino e 40% cursaram o ensino superior. Apenas 42 pessoas reconheceram o dia 18 de maio sendo o dia nacional da Luta Antimanicomial, 49 já ouviram falar sobre a Reforma Psiquiátrica e 96% acreditam que as ações realizadas ajudam a diminuir o preconceito sobre as doenças mentais. Concluiu-se que os participantes, em sua maioria, ainda desconhecem a história da reforma psiquiátrica do Brasil, revelando a necessidade de se desenvolver ações que contribuam para a desmistificação da loucura, para desenvolver indivíduos mais sensíveis à compreensão da dimensão do sofrimento psíquico.

Palavras-chave: Conhecimento. Comunidade. Saúde mental.
Relative activities of siloxane monomers toward the cation exchange resin-catalyst in the equilibration reactions
Authors: Govedarica M.N.
Published: May 2018

The relative activities of a number of siloxane monomers, both cyclic and
linear, toward the cation exchange resin-equilibration catalyst were
determined. The determination was based on the fact that when a particular
siloxane compound is added to an arbitrarily chosen equilibrate, it takes
part in the equilibration process, provoking certain viscosity changes of
the reaction mixture. Taking these viscosity changes as a measure of
activities, the following order was obtained: hexamethylcyclotrisiloxane >
hexamethyldisiloxane > octamethylcyclotetrasiloxane > one linear all-methyl
oligosiloxane of number average molecular weight of approximately 800 >
decamethylcyclopentasiloxane. The results obtained by using the described
viscosimetrical determination method were controlled by measuring the number
average molecular weights of the reaction mixtures at the beginning and at
the end of the equilibration process. The deviations of the experimentally
measured from the calculated values were less than 20 %, as was found in one
equilibration system. In most other systems the deviations were about
10%which is a very good result which strengthens the validity of the applied
determination method.
The influence of a cryoprotective medium containing glycerol on the lyophilization of lactic acid bacteria
Authors: Trsic-Milanovic Nada , Kodzic Aleksandar , Baras Josip , Dimitrijevic-Brankovic Suzana
Published: May 2018

The aims of liophilization (freeze-drying) of lactic acid bacteria are to
preserve pure cultures or to prepare starters for the dairy industry. In
both cases, the choice of the cryoprotectant is very important. In this
work, samples of Bifidobacterium breve A71 and Bifidobacterium bifidum BbTD
were freeze-dried in a new cryoprotective medium containing lactose,
gelatine and glycerol (medium B). The reference medium contained saccharose,
gelatine and skim milk (medium A). Before liophilization, the eutectic
points of both media were determined, because the products must be cooled to
a temperature below its freezing point. The success of the cryoprotectants
was estimated in terms of the number of surviving organisms after
lyophilization. Bifidobacterium breve A71 and Bifidobacterium bifidum BbTD
freeze-dried in mediaAandBshowed high survival rates. Bifidobacterium breve
A71 showed a greater percentage survival in combination with medium B than
with medium A. These results could be utilized in the manufacture of
Bifidobacterium breve A71 as a starter in the diary industry because it is a
human isolate which, except for acidification, has probiotic activity.
Antifungal activity of cinnamon and clove essential oils against button mushroom pathogens Cladobotryum dendroides (Bull.) W. Gams & Hooz and Lecanicillium fungicola var. fungicola (Preuss) Hasebrauk
Authors: Lukovic Jelena , Stepanovic Milos , Todorovic Biljana , Milijasevic-Marcic Svetlana , Duduk Natasa , Vico Ivana , Potocnik Ivana
Published: May 2018

Antifungal activity of two essential oils, cinnamon (Cinnamomum verum J.
Presl) and clove (Syzygium aromaticum (L.) Merrill & Perry), was evaluated
against Cladobotryum dendroides (Bull.) W. Gams & Hooz, and Lecanicillium
fungicola var. fungicola (Preuss) Hasebrauk, the causal agents of cobweb and
dry bubble disease of cultivated mushroom. Inhibitory and fungicidal
activity of the selected essential oils was assayed using three methods:
microdilution, macrodilution fumigant and macrodilution contact method.
Comparing all three methods, clove essential oil showed stronger activity
than cinnamon against both fungi, having minimum inhibitory concentration
(MIC) at the lowest concentrations tested (1.56, 0.02 and 0.1 ?l ml-1,
respectively). However, cinnamon oil was more toxic to L. fungicola var.
fungicola then to C. dendroides in all three methods. Both oils exhibited
stronger antifungal effects when used in the macrodilution fumigant than in
contact method. The results showed that both cinnamon and clove essential
oils have the potential for further in vivo experiments against L. fungicola
var. fungicola and C. dendroides and indicated a possible use of these oils
in integrated disease management in mushrooms.