bluuebunny/crossref_metadata_2025 huggingface dataset:
THE ESSENCE AND PECULIARITIES OF THE CONTENT OF PROFESSIONAL COMPETENCE OF OFFICERS – SPECIALISTS IN THE ORGANIZATION OF INTELLIGENCE AND INFORMATION WORK
Authors: Шаршаткін Данило
Published: April 2024

The professional competence of officers – specialists in the organization of intelligence and information work – is a set of knowledge, skills, abilities and personal qualities that allow them to effectively perform tasks of collecting, analyzing and processing information in the interests of security and protection of national interests. This competence consists of various components that cover technical, social and psychological aspects. The structure of professional competence of officers in the field of intelligence and information work should include technical knowledge, analytical skills, communication skills, leadership skills and ethical standards.The formation of all components of the professional competence of future officers – specialists in the organization of intelligence and information work involves high-quality professional training in higher military educational institutions, taking into account the requirements of the Ministry of Education and Science of Ukraine to the content of educational and professional programs and the requirements of the Ministry of Defense of Ukraine in terms of the general level of training of officers.171 № 1(36)2024The structure of professional competence takes into account various aspects and requirements related to the professional competence of officers in the field of intelligence and information work. At the same time, under the legal regime of martial law, the scope of functions assigned to officers of this specialty is significantly increasing, as military functions have been actualized, in particular, planning, organizing and conducting the main types of combined arms battle, organizing the main types of combat support of the unit, countering the enemy in the case of attacks or sabotage, use of firepower available to reconnaissance units, support of servicemen’s vital functions in autonomous conditions in various physical and geographical conditions during combat missions, etc.The effective formation of professional competence to future officers – specialists in the organization of intelligence and information work in higher military educational institutions involves taking into account a number of organizational and pedagogical conditions that cover aspects of content, practical activities, exchange of experience and involvement in research.
Pentingnya Pengembangan Media Berbasis Digital Pada Pembelajaran Bahasa Indonesia
Authors: Suryanti Enny , Tri Widayati Retno , Nugrahani Farida , Veronika Unun Pratiwi
Published: April 2024

Artikel ini mengkaji pentingnya memperoleh keterampilan media digital untuk mencapai kefasihan berbahasa Indonesia. Artikel ini merupakan hasil penelitian yang dilakukan dengan menggunakan metodologi yang mengandalkan kajian komprehensif terhadap materi yang ada. Temuan penelitian menunjukkan bahwa pemanfaatan media dalam pembelajaran bahasa Indonesia membawa beberapa manfaat yang signifikan. Diantaranya adalah pengembangan keterampilan digital di kalangan peserta didik, dampak media berbasis digital yang terbukti terhadap pemerolehan bahasa Indonesia, pengurangan keterbatasan seperti ruang, waktu, dan jarak melalui media berbasis digital, peningkatan kosa kata peserta didik melalui media digital. berbasis media, dan pemberian stimulus dan motivasi kepada peserta didik melalui penggunaan media berbasis digital. Arti penting penggabungan media berbasis digital dalam pembelajaran bahasa Indonesia terletak pada perlunya guru melakukan inovasi dengan menciptakan dan memanfaatkan media berbasis digital yang dirancang khusus untuk pembelajaran bahasa Indonesia. Pentingnya media berbasis digital ini dikembangkan dengan menggunakan bahasa Indonesia sendiri. Perlu diketahui bahwa media berbasis digital dapat memberikan dampak positif dan negatif. Selain itu, terdapat empat model penelitian yang cocok untuk pengembangan media berbasis digital dalam pembelajaran bahasa Indonesia, yaitu model Hannafin & Peck, model Thiagarajan atau 4D, model Dick & Carey, dan model ADDIE. Artikel ini mengusulkan integrasi media digital ke dalam pedagogi pengajaran bahasa Indonesia oleh para pendidik. Selain itu, disarankan untuk menggunakan salah satu dari empat kerangka studi yang disarankan untuk tujuan kemajuan.
The Possibility of Destruction of Cellular NADPH in the Presence of Free Fe(II) Ion, Arsine, and Other Hazardous Species
Authors:   Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran., Siadati Seyyed Amir , Ebrahimzadeh Mohammad Ali ,   Department of Medicinal Chemistry, Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran., Babanezhad Esmaeil ,   Department of Environmental Health, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.
Published: April 2024

Background: As the nicotinamide adenine dinucleotide phosphate (NADPH) is the key natural electron generator of the alive cells, investigation of the possibility of inactivation or even destruction of it by hazardous chemical molecules or ions seems to be very important. Methods: Due to this, in this project, the behavior of NADPH in the presence of some chemical species containing Fe(II) ion, arsine, phosphoric acid, and some low weight alcohols have been investigated by using the density functional theory (DFT) method. Results: Comparison of the results of the potential energy surface (PES) study showed that adsorption of methanol, ethanol, normal propanol, H3PO4, arsine and Fe(II) ion by NADPH release -23.19 kcal mol-1, -23.03 kcal mol-1, -23.30 kcal mol-1, -35.04 kcal mol-1, -53.03 kcal mol-1, and -161.59 kcal mol-1 energy, respectively. Conclusion: It indicates that absorption, and even destruction of NADPH by a free Fe(II) ion is very favorable in view of thermodynamics. Somehow, such energy release could make this process irreversible. Also, the geometrical results show that during the adsorption of iron ion by the NADPH, the phosphate bridge breaks and the molecule decompose in two different parts.
Designing Specific Primers for Amplification and Quantitative Analysis of the GPR120 and PPARγ Genes
Authors:   Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Kurdistan Regional Blood Transfusion Center, Sanandaj, Iran., Lotfi Ramin , Salari Farhad ,   Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Published: April 2024

Background: Designing the primer pairs is one of the most important factors in the amplification and quantitative analysis of the nucleic acid sequences of interest. Using in silico methods, the present study intends to design highly specific primers for quantitative analysis of the genes with minimum expression. To achieve this aim, we selected two candidate genes with little expression, namely, G-protein coupled receptor 120 (GPR120) and peroxisome proliferator-activated receptor-γ (PPARγ), in peripheral blood leukocytes of healthy volunteers. Methods: Peripheral blood was collected from 30 healthy volunteers. Primers for GPR120 and PPARγ were designed using online websites (UCSC, OligoCalc, and OligoAnalyzer) and the primer designing tool (NCBI). Total RNA extraction and cDNA synthesis were done using commercially available kits based on manufacturer instructions. Finally, the melting curve analysis of GPR120 and PPARγ was assessed using the quantitative real-time PCR method. Results: The in silico gene expression investigation revealed that GPR120 and PPARγ have minimal leukocyte expression. Besides, the melting curves analysis for both genes in the studied individuals showed only one melting peak, confirming the specific amplification of the desired genes. Conclusion: Altogether, the study findings indicated that we could utilize the peripheral blood sample for assessing the gene expression and amplification of omega-3 fatty acids receptors, i.e. GPR120 and PPARγ as two candidate genes with very low expression in leukocytes.
Upregulated Expression of Runt-related Transcription Factor 3 and Interferon Regulatory Factor 4 Genes in Patients With Ankylosing Spondylitis
Authors:   Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran., Assadiasl Sara , Soleimanifar Narjes ,   Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran., Rostamian Abdolrahman ,   Department of Rheumatology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran., Sadr Maryam ,   Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran., Mazari Abeda ,   Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran., Nicknam Mohammad Hossein ,   Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Published: April 2024

Background: Ankylosing spondylitis (AS) is a debilitating autoimmune disease presented by chronic inflammation of large joints and central skeleton. The role of various immune cells, including T cell subsets, has been studied in the pathogenesis of AS. Two critical transcription factors, runtrelated transcription factor 3 (RUNX3) and interferon regulatory factor 4 (IRF4), are involved in the differentiation and function of T lymphocytes. This study compared the gene expression level ofRUNX3 and IRF4 between patients with AS and healthy subjects to understand the impact of these factors in the immunopathogenesis of the disease. Methods: Thirty patients with AS and 30 age- and gender-matched healthy individuals were recruited to the study, and expression of RUNX3 and IRF4 genes was evaluated using the reverse transcription polymerase chain reaction (RT-PCR) technique in their peripheral blood. Results: The expression of RUNX3 and IRF4 genes in AS patients was significantly upregulated compared to the healthy controls (P=0.03 and 0.025, respectively). In addition, there was a direct correlation between IRF4 gene expression and bath ankylosing spondylitis global score (BAS-G) (correlation coefficient=0.38, P=0.04) Conclusion: Gene expression of RUNX3 and IRF4 transcription factors involved in T cells’ differentiation and function was increased in AS. These findings might have prognostic and therapeutic value.
Association of Lipid Profile and Inflammatory Markers With COVID-19 Severity and Outcome
Authors:   Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran., Khoshgoeian Amirhossein , Bahar Adele ,   Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran, Kashi Zahra ,   Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran., Khasayesi Mina ,   Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran., Yahoo Torghabe Shima ,   Department of Basic Sciences, Faculty of Animal Sciences and Fisheries, Sari Agricultural Sciences and Natural Resources University, Sari, Iran., Moosazadeh Mahmood ,   Gastrointestinal Cancer Research Center, Non-Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran., Hosseini-khah Zahra ,   Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Published: April 2024

Background: COVID-19 is a highly contagious disease that has already affected millions of people worldwide. Proinflammatory cytokines in COVID-19 infection change lipid metabolism and profile. This study investigates the association between lipid profile and inflammatory markers with the severity and outcome of COVID-19 patients referred to a teaching hospital in Mazandaran Province, Iran, during April-May and July-August 2020. Methods: This study was conducted on 140 patients with COVID-19 based on their clinical symptoms, imaging results, and laboratory findings. Patients were categorized as severe and non-severe groups based on the Centers for Disease Control and Prevention criteria. Blood samples (5-7 mL) were collected from patients after 12 hours of fasting. Serum triglycerides, cholesterol, highdensity lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C) levels were measured using Pars Azmoon Kits (Hitachi Ltd). Results: Of 140 COVID-19 patients, 33.57% had severe and 66.43% had non-severe disease. Patients with severe disease had a significantly lower mean LDL serum level than those with non-severe involvement (56.39±3.62 vs 70.10±3.74 mg/dL) (P=0.023). Patients in the intensive care units had significantly lower HDL, LDL, and cholesterol serum levels than those hospitalized in other parts (P=0.006, P=0.002, and P=0.002, respectively). There was a significant negative correlation between HDL serum level and C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) (P=0.0001 and r=-0.482) and (P=0.01 and r=-0.258), respectively. Additionally, there was a significant correlation between cholesterol level and CRP, triglycerides, and ESR (P=0.016 and P=0.02, respectively). Conclusion: The present study highlights the potential of lipid profiling as a cost-effective and accessible marker to assess COVID-19 severity and prognosis.
Hegemonic Masculinity and Homosexuality in Contemporary Indonesian Motion Picture
Authors: Tarihoran Rezky Khoirina , Wardana Muhammad Kiki
Published: April 2024

Homosexuality in Indonesia is examined in through its contemporary motion picture. The data for this study came from the motion picture named Arisan! released in 2003. This study incorporated Foucault's theory of sexuality as a social construction, Connell's Hegemonic Masculinity, and A,J Greimas’ Narrative Structuralism . Numerous findings can be found in the research, including the actantial model and functional model of the story in Arisan!. Additionally, this research discovered that homosexuality in Indonesia is subordinated.
INFLUENCE OF THE MARTIAL LAW ON THE CAUSES AND CONDITIONS OF COMMITMENT OF CRIMINAL OFFENSES RELATED TO ILLEGAL USE OF BUDGET FUNDS
Authors:   Penitentiary Academy of Ukraine, Chernihiv, Ukraine, Petrenko S.
Published: April 2024

The article addresses to the factors that affect crime. Attention is drawn to the determinants of crime in the budgetary sphere. The organization of an effective crime prevention system in the field of illegal use of budget funds was and is one of the most pressing social problems of our country. A large number of different criminological studies were devoted to the study of the determinants of budget crime, on the basis of which the state developed practical measures. At the same time, the level of this type of crime does not decrease. Vice versa, as the statistical data of law enforcement agencies evidenced, numerous publications in mass media and investigations by journalists, the problem exists and remains relevant. A new challenge for the law enforcement system, the state in general, was the beginning of the active phase of russia’s war against Ukraine and since the introduction of the legal regime of martial law. In this regard, budget crime also underwent changes, creating new forms and means of committing it. This, in turn, requires a study of the influence of martial law on the determinants of committing criminal offenses related to the illegal use of budget funds. Key words: martial law, budget funds, crime, determinants, criminogenic factors, budget crimes, illegal use of budget funds.
PUBLIC DANGER OF DRUG ADDICTION AS A CRIMINOLOGY FACTOR OF DECRIMINALIZATION INEXPEDIENCY OF ART. 309 OF THE CRIMINAL CODE OF UKRAINE
Authors:   Academy of the State Penitentiary Service,  Chernihiv, Ukraine, Ivashko S. , Voroshylova D. ,   Penitentiary Academy of Ukraine,  Chernihiv, Ukraine
Published: April 2024

The article provides the author’s justification of the decriminalization inexpediency of Art. 309 of the Criminal Code (CC) of Ukraine through a criminological analysis of the public danger of drug addiction as a background phenomenon for crime. The article also analyzed the Draft law No. 9028 on amendments to the Criminal Code of Ukraine and the Code of Ukraine on Administrative Offenses regarding the improvement of liability for illegal production, manufacture, acquisition, storage, transportation or forwarding of narcotic drugs, psychotropic substances or their analogues without the purpose of sale. Considering the fact, the Draft law proposes to exclude Art. 309 from the CC of Ukraine, replacing criminal liability to administrative liability for committing of certain illegal actions, it is emphasized that a number of problematic issues have arisen today regarding the implementation of such a draft law, since both society and state bodies are not ready for such changes. The conducted analysis showed that the decriminalization of Art. 309 of the CC of Ukraine has different points of view. Some scientists believe that decriminalization can help reduce drug addiction and drug-related crime, as instead of being prosecuted, people will be able to get medical help and support for responsible drug use, and reduce pressure on the justice system. In its turn, a lack of continence in the form of sufficient punishment threat will reproduce committing of a number of new, more serious criminal offenses. That is why the authors of the article believe that the decriminalization of drug use can confirm the negative social consequences of drug addiction and can send the wrong message to young people on drug use. Concerns have also been expressed that such decriminalization may lead to an increase in drug use and an increase in the risk of harmful effects on people’s health, and even more so will lead to committing of other, more serious criminal offenses. Key words: criminal offense, crime, criminal misdeed, criminal responsibility, administrative offense, administrative responsibility, decriminalization, background phenomena for crime, marginal environment, narcotic drugs, drug addiction, juvenile delinquency, involvement of juveniles to narcotic drugs use, criminogenic factors, determinants, self-serving violent crime, violent criminal offenses, criminal groups, criminal offenses in the domestic (family) sphere, prevention, police officers, evidence.
LEGAL STATUS OF PRISONERS OF WAR IN UKRAINE
Authors:   Institute of Professional Development,  Penitentiary Academy of Ukraine,  Chernihiv, Ukraine, Mytska O.
Published: April 2024

The article is devoted to the understanding of the legal status of prisoners of war. In order to establish the legal status of prisoners of war, the author analyzes and argues that captivity is a phenomenon which is accompanied by restrictions on the freedom of persons who fall (claim) to have the legal status of prisoners of war and were involved in an armed conflict, with the aim of preventing their participation in hostilities in the future. The author clarifies the role of participants in an international armed conflict, which in international humanitarian law are divided into military and civilian combatants and non-combatants. Only combatants, i.e., those persons involved in an interstate conflict, can become prisoners of war. The main difference between a non-combatant and a combatant is that the above-mentioned persons have personal weapons, but can use them only for self-defense. If they participate in hostilities, they acquire the status of combatants. The legal status of a person is a system of rights, freedoms, obligations, and responsibilities enshrined in legal acts and guaranteed by the state, according to which an individual, as a subject of law (i.e., as one with legal personality), coordinates his or her behavior in society. The legal status of: a) citizens of Ukraine; b) foreigners; c) stateless persons; d) persons granted asylum. According to the nature of legal regulation, the legal status is a) general; b) sectoral (individual), c) special. The legal status of prisoners of war applies only to those persons who have not violated the rules and customs of war and are not subject to prosecution under the criminal law of Ukraine. In general, the legal status is formed by combining subjective rights, legitimate interests and legal obligations. The constituent elements of the legal status of prisoners of war are rights, obligations and prohibitions. Prisoners of war are special subjects of law, as they are under international legal protection and endowed with a special legal status regulated by both national legislation and regulations of international humanitarian law. Key words: war, prisoners of war, captivity, legal status of a person, international conflict, rights, obligations, prohibitions, foreigners, combatants, non-combatants.
Manusia, Proses, dan Teknologi sebagai Komponen Utama Penyelenggaraan Pelatihan bagi ASN secara Blended Learning
Authors: Hadi Tjahyono Hendriyanto , Darto Mariman
Published: April 2024

Penelitian ini bertujuan untuk mengungkapkan parameter atau karakteristik terkait unsur manusia, unsur proses, dan unsur teknologi yang dibutuhkan untuk menyelenggarakan pelatihan secara blended learning yang efektif. Metodologi penelitain mengambil paradigma interpretif (interpretivism) dengan metode studi kasus yaitu penyelenggaraan Pelatihan Kepemimpinan Nasional. Berdasarkan survei kualitatuf, wawancara informan, observasi, dan kajian dokumen ditemukan dan dikonklusikan bahwa efektivitas penyelenggaraan pelatihan secara blended learning sangat ditentukan oleh tiga parameter utama pendukungnya, yaitu yang terkait dengan unsur manusia, unsur proses, dan unsur teknologi. Masing-masing unsur tersebut mencakup beberapa komponen yang perlu disiapkan atau diperhatikan dalam penyelenggaraan pelatihan blended learning. Model penelitian yang dihasilkan dalam penelitian ini mempunyai implikasi teoritis karena dapat menjadi obyek penelitian selanjutnya secara kuantitatif, sedangkan secara praktis, hasil penelitian ini dapat dimanfaatkan secara langsung oleh instansi penyelenggara pelatihan baik yang sudah maupun yang belum pernah menyelenggarakan pelatihan secara blended learning, dan bagi para widyaiswara sebagai pemicu untuk mengembangkan wawasan dan kompetensinya di bidang paedagogi digital. Terdapat keterbatasan dalam penelitian ini karena pengungkapan lebih ke ranah penyelenggaraan Pelatihan Kepemimpinan walaupun sebenarnya hasil penelitian ini dapat digeneralisasi untuk pelatihan yang lain, yaitu dengan menambahkan kajian yang melibatkan informan berpengalaman di penyelenggaraan pelatihan lain agar hasil penelitian dapat valid untuk diterapkan di semua jenis pelatihan bagi ASN atau bahkan pelatihan pada umumnya.
Kata Kunci: Pelatihan blended learning, Pelatihan Kepemimpinan Nasional, efektivitas pelatihan, paedagogi digital.
Transformational Leadership: Peran Pimpinan Dalam Transformasi Tata Kelola Kearsipan di Lingkungan Lembaga Administrasi Negara
Authors: Zuhruf Al
Published: April 2024

Peran pimpinan sangat penting dalam sebuah organisasi khususnya instansi pemerintah. Bahwasannya peran pimpinan dapat mempengaruhi dan menentukan arah dan tujuan dari suatu organisasi. Pada 2017 kondisi kearsipan Lembaga Administrasi Negara (LAN) sangat buruk, ditandai dengan sulitnya mencari arsip yang dibutuhkan, hasil evaluasi Arsip Nasional Republik Indonesia (ANRI). Akan tetapi selang beberapa tahun LAN dapat mentransformasikan kearsipannya yang dibuktikan dengan peningkatan nilai hasil pengawasan kearsipan dan penghargaan-penghargaan yang didapatkan. Tentu sinergi antara organisasi, pimpinan, dan pegawai merupakan faktor pendorong dari keberhasilan transformasi tata kelola kearsipan LAN. Untuk melihat lebih lanjut, penelitian ini akan mengkaji peran pimpinan dalam transformasi tata kelola kearsipan. Metode penelitian yang digunakan adalah kualitatif yang akan mendeskripsikan bagaimana peran pimpinan berdasarkan perspektif teori kepemimpinan transformasional. Hasil dari penelitian ini adalah bahwa pimpinan LAN telah memenuhi 4 komponen kepemimpinan transformasional yakni 1) idealized influence; 2) inspirational motivation; 3) intellectual stimulation; dan 4) individual consideration. Artinya peran pemimpin transformasional berdampak positif bagi kemajuan organisasi.
Kata Kunci: Kepemimpinan Transformasional, Kearsipan, Tata Kelola Arsip
Micro-fundamentos de la corrupción: motivaciones individuales, racionalidad y comportamiento corrupto
Authors:   Universidad Autónoma de Querétaro, Sarsfield Rodolfo
Published: April 2024

La teoría de la elección racional ha dominado durante mucho tiempo el estudio de la corrupción y el diseño de las políticas y prácticas anticorrupción. A pesar del auge, aceptación y difusión de este enfoque, muchos países, no obstante, no han logrado avances en la reducción del comportamiento corrupto (Heywood 2017; Marquette y Pfeiffer 2015; Mungiu-Pippidi, 2023; Per-sson, Rothstein y Teorell 2013; Rose-Ackermann y Palifka 2016). Una razón de tal fracaso podría ser que los supuestos de elección racional sobre las motivaciones de los individuos son demasiado simplistas. Una consecuencia que se desprende de tal estado de cosas es que, por lo tanto, el estu-dio de la lógica subyacente que lleva a los individuos al comportamiento corrupto sea un aspecto central para la agenda de investigación sobre la corrupción. Dentro de este panorama, este artículo busca presentar la discusión en la literatura sobre las motivaciones de los individuos que condu-cen (o lo alejan) de la conducta corrupta, poniendo especial énfasis en el debate entre el (nuevo) enfoque de la elección racional, la psicología cognitiva, la psicología política y la economía del comportamiento.
Una propuesta democrática de control y rendición de cuentas en la gestión municipal
Authors:   Centro de Investigación y Docencia Económicas, L. Moheno Ignacio
Published: April 2024

Este ensayo aborda la cuestión del control y la rendición de cuentas municipal y pro-pone un esquema de buena gobernanza que involucra cuatro variables: la presencia de elecciones periódicas; la disposición burocrática hacia la transparencia; la disponibilidad de información gu-bernamental, y la disposición ciudadana a participar en los mecanismos de control y rendición de cuentas. Procede luego a explicar las posibilidades y los problemas que el esquema entraña sobre la base de tres personas conceptuales: el burócrata, el ciudadano y el político, que pertenecen, res-pectivamente, a sendos modelos organizacionales de lo público: eficiencia, legitimidad y eficacia. Palabras clave: control, rendición de cuentas, transparencia, burócrata, ciudadano, político, eficiencia, legitimidad, eficacia, ética pública.
El control del poder en el Estado de derecho: Importancia de los datos en el combate a la corrupción
Authors:   Universidad Nacional Autónoma de México, Uvalle Berrones Ricardo
Published: April 2024

El objetivo de este artículo es analizar y explicar, en el marco del Estado de derecho, la rendición de cuentas, el papel de los políticos y los administradores públicos, así como la relevan-cia de los datos para erradicar la corrupción. Los datos favorecen la comprensión específica de las políticas públicas mediante el conocimiento descriptivo, el cual es indispensable para superar vacíos y ambigüedades, a fin de producir evidencias convincentes que permitan la formulación de argumentos para racionalizar con eficacia la lucha contra la corrupción.
Perbedaan Pengaruh Faktor Makro Terhadap Sektor Saham Industri
Authors: Tahmat Tahmat , Garnia Erna , Riyadi Deden Rizal , Azzahra Risma Ristani Putri , Lisaumi Siti Riyyan
Published: April 2024

Penelitian ini bertujuan untuk menguji perbedaan pengaruh faktor makro terhadap return saham sektor perindustrian pada masa kepemimpinan Susilo Bambang Yudhoyono dan Joko Widodo. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan deskriptif dan verifikatif dengan menggunakan data sekunder. Pengujian yang digunakan pada penelitian meliputi pemilihan model common effect, random effect dan fixed effect, uji asumsi klasik, uji hipotesis, koefisen determinasi serta uji beda pengaruh menggunakan dummy variabel. Perbandingan pada kelompok return tinggi SBY dengan JKW menunjukkan bahwa hanya indeks global terdapat perbedaan pengaruh pada return tinggi SBY dan JKW. Sedangkan perbandingan pada kelompok return rendah SBY dengan JKW menunjukkan bahwa makroekonomi dan sumber daya saing terdapat perbedaan pengaruh pada return rendah SBY dan JKW sedangkan indeks Global, harga minyak dunia, indeks China dan indeks Arabian tidak terdapat perbedaan pengaruh pada return rendah SBY dan JKW.
Pengaruh Kualitas Layanan dan Promosi Penjualan terhadap Keputusan Pembelian pada Kedai Konci Cimahi
Authors: Kharisman Agrie Wahyudi , Setiawan Desta Arie , Ubaidillah Ahmad Zulfahmi , A Indra Wiraseni
Published: April 2024

Penelitian ini mengkaji dampak kualitas layanan dan promosi terhadap keputusan pembelian konsumen di industri coffee shop di Kota Cimahi. Dengan menggunakan metode statistika deskriptif dan metode asosiatif, data dianalisis dari 96 responden yang merupakan konsumen Kedai Konci. Hasil penelitian menunjukkan bahwa kualitas layanan yang tinggi dan promosi yang efektif memiliki pengaruh yang signifikan terhadap keputusan pembelian konsumen. Penurunan penjualan yang dialami Kedai Konci diduga disebabkan oleh penurunan kualitas layanan dan kurangnya efektivitas promosi. Oleh karena itu, disarankan kepada pengusaha coffee shop untuk memberikan layanan berkualitas tinggi yang responsif terhadap kebutuhan konsumen dan meningkatkan strategi promosi yang menarik dan relevan. Penelitian ini memberikan wawasan bagi pengusaha coffee shop dalam menghadapi persaingan yang ketat di industri ini dan memberikan landasan bagi pengembangan strategi pemasaran yang lebih efektif.
Bisnis Model Pertanian Organik Berbasis Ekonomi Sirkular di Kabupaten Bandung Barat
Authors: Solihin Rici , Koeswandi Tika
Published: April 2024

FAM Organic adalah usaha Pertanian Organik yang memiliki value proposition Healthy People, Healthy Environment, dan Healthy Living. Penelitian ini bertujuan untuk menganalisis Business Model Canvas dari PT X, sebuah usaha pertanian organik yang beroperasi di Kabupaten Bandung Barat. Metode penelitian ini melibatkan studi kasus, studi literatur dan depth interview terkait dengan model bisnis PT X. Hasil penelitian mengungkap bahwa PT X memiliki segmen pelanggan yang terfokus pada konsumen kalangan menengah atas yang mengutamakan gaya hidup sehat. Inti kegiatan operasional PT X mencakup produksi Sayuran Organik, penjualan produk, edukasi pertanian organik. Sumber pendapatan PT X berbeda dengan pertanian konvensional karena tidak hanya menjual hasil panen tetapi juga dari pelatihan, farm tour, gardening kit dan lisensi. Hasil penelitian ini memberikan wawasan mendalam tentang model bisnis PT X dan memberikan landasan untuk rekomendasi strategis yang dapat meningkatkan keberlanjutan dan daya saing usaha pertanian organik di Kabupaten Bandung Barat.
Submission to the Inter-American Commission on Human Rights During its Promotional visit to Canada
Authors: Campbell-Duruflé Christopher
Published: April 2024

Canada’s system to incorporate international law into its domestic law has been the object of a long line of criticism. Your visit and the IACHR’s ongoing engagement with Canada provide a momentous opportunity to call for 1) stronger engagement with and 2) more effective implementation of the human rights instruments of the Inter-American system. I discuss both issues in turn and provide some final thoughts by way of conclusion.

December 14th, 2023 
Survey of the Effect and Medical Application of Electromagnetic Radiation
Authors: Ojobeagu A. O. , Vwavware Oruaode Jude , Ossai C. , Akpoyibo O. , Chikwendu A. O.
Published: April 2024

Every electronic gadget that has become a part of daily life has had its electromagnetic radiation thoroughly examined. The maximum emission level and the minimum distance at which each device has an impact have been examined. Even in remote locations far from transmitters, the radio frequency field strength meter is an incredibly sensitive tool that can detect RF background with accuracy. The meter's display shows the true power density right away. The internal detection method of this meter produces a flat response across a very large frequency range, in contrast to other inexpensive field strength meters whose frequency response is dependent on the properties of an external antenna.Accuracy between 30 MHz and 2.4 GHz for FM, TV, and cell tower frequencies is +/-25%. Between 0.5 MHz and 3 GHz, the sensitivity is 50% (-3 dB) lower. At 5 GHz, sensitivity is 25%. In other words, when detecting microwaves at that high a frequency, you have to multiply the reading by 4. The sensitivity is roughly 10% at 10 GHz.).
A Study of a Class Continuous SIR Epidemic Model with History
Authors: Olopade Isaac A. , Mohammed I .T. , Philemon M. E. , Akinwumi T. O. , Sangoniyi S. O. , Adeniran G. A. , Ajao S. O. , Adewale S. O.
Published: April 2024

The SIR model, an epidemiological model, divides a population into three compartments: Susceptible (S), Infected (I), and Recovered (R). It is widely used to understand the spread of infectious diseases and predict epidemic outcomes based on factors such as transmission rates and population dynamics. A deterministic epidemic mathematical model to describe the transmission dynamics of an infectious disease was constructed and analyzed by incorporating memory term which provides information on the current and past disease states. The model revealed two key equilibria: a disease-free equilibrium and an endemic equilibrium. The calculated basic reproductive number R0, was employed to establish that when R0<1, the disease-free equilibrium is locally asymptotically stable, while the endemic equilibrium is locally asymptotically stable when R0>1. Additionally, we explored the global stability of these equilibria using Lyapunov functions and Dulac's method, respectively. To validate our analytical findings, we conducted numerical simulations of the model which show the importance of history in the dynamic spread and elimination of disease.
Bacterial and Fungal Isolates from Crude Oil Polluted Sediment in Eniong River, Itu, Nigeria
Authors: Egbomuche R. C. , Ekwenye U. N. , Akinjogunla O. J. , Ikeh A. O. , Akpan S. B.
Published: April 2024

The need to know the level of contamination of radioactive elements, especially Microbial populations are crucial for the environment, providing vital ecosystem services such as biogeochemical cycling, decomposition, and degradation, which essential vital for the survival of all life forms on Earth. This study investigated the heterotrophic bacterial and fungal isolates in crude oil polluted sediment from the Eniong River using standard conventional analytical and culture-dependent techniques. The mean total heterotrophic bacterial (THBC) and mean total fungal counts (THFC) in sediment samples from the three stations of Eniong river sediment was 9.3 x 104CFU/g and 2.4 x 104 CFU/g, respectively. The heterotrophic bacterial count was highest in location A (upstream) and lowest in location C (downstream) while the lowest fungal count was obtained in location B (midstream) and highest in location C (downstream). The results revealed diverse bacterial and fungal assemblages and ecosystem's richness in microbial diversity. Twelve (12) bacterial species from the genera Staphylococcus, Salmonella, Shigella, Escherichia, Bacillus, Klebsiella, Micrococcus, Aeromonas and Pseudomonas were isolated. The eight (8) fungal species belonging to genera Aspergillus, Penicillium, Rhizopus, Geothrichium, Candida and Mucor were obtained. Bacillus cereus was the most prevalent bacterial isolate, accounting for 16%, while the least isolated bacteria were Aeromonas sp. and Salmonella sp. (4%). The most isolated fungi was A. niger (31.8%), while A. fumigatus (13.6%) was the least occurring fungal isolates. The findings clearly demonstrated that the sediment of the Eniong River provided a unique ecological niche that supports a variety of microorganisms.
The Effects of Course Modality on Student Satisfaction and Academic Outcomes at a Liberal Arts College During the COVID-19 Pandemic
Authors: Dong Suhua
Published: April 2024

Using student self-reports on a survey and objective records of academic achievement, I examined the effects of course modality on student satisfaction and academic outcomes at a selective liberal arts college in spring 2021. I compared three groups of undergraduates (N = 729) based on their predominant course modality: Online-Class Group, Residential Blended Learning Group, and Residential In-Person-Class Group. After controlling for gender, race/ethnicity, class level, and socioeconomic status, course modality demonstrated significant main effects on all three satisfaction variables and sense of connection a student felt to the institution. The Online-Class Group reported the lowest satisfaction with level of academic challenge, quality of teaching, and overall quality of academic experiences; it also reported the weakest sense of connection. The Residential Blended Learning Group differed from the Residential In-Person-Class Group on one variable: satisfaction with quality of teaching, on which the former reported lower satisfaction. Course modality did not affect a student’s grade point average; although it interacted with gender in its effect on the number of course units a student passed, no subgroup difference by course modality and gender was significant. This study indicates that online classes and blended learning, especially the latter, have potential at liberal arts colleges.
Time from diagnosis to treatment has no impact on survival in newly diagnosed acute myeloid leukemia treated with venetoclax-based regimens
Authors: Baden David , Zukunft Sven , Hernandez Gema , Wolgast Nadine , Steinhauser Sophie , Pohlmann Alexander , Schliemann Christoph , Mikesch Jan-Henrik , Steffen Bjorn , Sauer Tim , Hanoun Maher , Schafer-Eckart Kerstin , Krause Stefan W. , Hanel Mathias , Einsele Hermann , Jost Edgar , Brummendorf Tim H. , Scholl Sebastian , Hochhaus Andreas , Neubauer Andreas , Burchert Andreas , Kaufmann Martin , Niemann Dirk , Schaich Markus , Blau Wolfgang , Kiani Alexander , Gorner Martin , Kaiser Ulrich , Kullmer Johannes , Weber Thomas , Berdel Wolfgang E , Ehninger Gerhard , Muller-Tidow Carsten , Platzbecker Uwe , Serve Hubert , Bornhauser Martin , Rollig Christoph , Baldus Claudia D , Fransecky Lars
Published: April 2024

In newly diagnosed acute myeloid leukemia, immediate initiation of treatment is standard of care. However, deferral of antileukemic therapy may be indicated to assess comorbidities or pre-therapeutic risk factors. We explored the impact of time from diagnosis to treatment on outcomes in newly diagnosed acute myeloid leukemia undergoing venetoclax-based therapy in two distinct cohorts.
By querying the Study Alliance Leukemia database and the global health network TriNetX, we identified 138 and 717 patients respectively with an average age of 76 and 72 years who received venetoclax-based firstline therapy. When comparing patients who started treatment earlier or later than 10 days after initial diagnosis, no significant difference in median overall survival was observed - neither in the SAL cohort (7.7 vs. 9.6 months, p=.42) nor in the TriNetX cohort (7.5 vs. 7.2 months, p=.41). Similarly, severe infections, bleeding, and thromboembolic events were equally observed between early and later treatments, both in the overall patient groups and specific subgroups (age ≥75 years or leukocytes ≥20x109/L).
This retrospective analysis indicates that delaying the start of venetoclax-based therapy in newly diagnosed acute myeloid leukemia might be a safe option for selected patients, provided that close clinical monitoring is performed.
Evaluation of the ATM L2307F germline variant in 121 Italian pedigrees with familial myeloproliferative neoplasms
Authors: Borsani Oscar , Jäger Roland , Pietra Daniela , Flieder Ines , Riccaboni Giacomo , Kralovics Robert , Rumi Elisa
Published: April 2024

Not available.
The New Media, an Ironic Reality as a Review of Social Consciousness in Nigerian Movies: A Case Study of Femi Adebayo’s Jagunjagun
Authors: Afolabi Amos Adelekan  , Taiwo Adekemi Agnes
Published: April 2024

This paper examines the new media as a set to make viral or bring to the knowledge of what is happening in our society within a short period of time. This paper uncovers the hidden biases and brings out the ironic reality or awakens the social consciousness of the people through the movie Jagunjagun produced by Femi Adebayo. In achieving this, the paper adopted social contructionism theory to critically analyse the movie.  However, the qualitative research method through a content analysis of Femi Adebayo’s movie Jagunjagun   is used with the objectives of analyzing the effectiveness of the new media to uncover the hidden biases in the movie and at the same time, awakens the social consciousness of the people living in the same society. Consequently, it is discovered that the movie (Jagunjagun) is full of ironic reality of the Nigerian social political milieu.
“Winning the Peace”: The Role of International Peace Settlements in the Creation of World Orders – A “Geopolitical Marxist” Perspective
Authors: Edwards Jack
Published: April 2024

For the discipline of International Relations (IR), the study of International Peace Settlements (IPS) for the organization of postwar international orders has thus far primarily been the purview of realist, liberal, and constructivist approaches. To date, Marxist approaches have tended to either ignore the significance of IPS in the formation of new global orders or have been inscribed into longer-term overarching processes – namely, the reified consequences of the development of capitalism. These proclivities have had the unwelcome effect of subsuming the role historical agents have played in the devising of international ordering strategies under preordained universal “laws of motion” and downplaying the broader efficacy of foreign policymaking in the building of world order. This paper proposes to rectify this Marxist lacuna by highlighting how adopting an approach that elaborates on the principles of Geopolitical Marxism (GPM) in IR can overcome these shortcomings. The paper argues that a radical historicist methodology for analysing these important world-historical junctures retrieves the significance of contextualized agency within the historical materialist tradition and overcomes the issues beholden to structuralist Marxist approaches.
DEVELOPMENT OF A FAST LIQUID CHROMATOGRAPHY METHOD WITH A CHEMOMETRIC APPROACH BASED ON BOX-BEHNKEN DESIGN FOR THE DETERMINATION OF ANTIDEPRESSANTS IN PHARMACEUTICAL FORMULATIONS
Authors: Yıldırım Sercan , Özyiğit Tuğçe
Published: April 2024

Objective: The objective of this work was to develop a liquid chromatographic method for the quantification of antidepressants, namely duloxetine (DXN), fluoxetine (FXN), citalopram (CIT), paroxetine (PXN), and sertraline (SRN), by a chemometric approach based on Box-Behnken design.
Material and Method: After initial experiments to determine significant parameters, a Box-Behnken design consisting of 17 experiment sets was carried out. All separations were conducted using an Agilent Poroshell 120 EC-C18 analytical column (75 mm × 4.6 mm × 2.7 µm).
Result and Discussion: The optimum levels of pH, acetonitrile ratio, and flow rate were determined with the desirability function as 2.7, 38%, and 1.1 ml/min, respectively. The differences (<8%) between predicted optimum responses and experimentally obtained results proved the model's suitability. Limits of detection and limits of quantification values were in the ranges of 0.17-0.29 µg/ml and 0.53-0.89 µg/ml, respectively. The feasibility of the technique was proven by analyzing PXN and DXN formulations.
Visual habitat selection by juvenile fish in response to seagrass with different structural complexity
Authors: Castro-Fernández J , Hinz H , Castejon-Silvo I , Catalán I , Disdier-Gómez JM , Moranta J , Ruiz-Frau A , Grau A , Terrados J
Published: April 2024

Seagrass meadows fulfil an essential ecosystem service by providing nursery habitats to various fish species. However, the habitat features driving this function remain insufficiently explored. Nevertheless, this knowledge is essential to quantify the ecosystem service provision, inform restoration efforts, and address the impact of habitat loss and fragmentation on this key coastal habitat. In this study, habitat selection experiments were conducted with 2 Mediterranean juvenile fish species (the East Atlantic peacock wrasse Symphodus tinca and the annular seabream Diplodus annularis), usually associated with Posidonia oceanica beds, to evaluate if they actively select seagrass habitats based on their structural complexity. Juvenile fish movement was recorded and tracked when visually exposed to multiple artificial habitat configurations within an experimental aquarium to determine the proportion of time spent near each habitat. Both species exhibited a clear affinity towards vegetated (seagrass mimics) habitats in comparison to unvegetated areas, demonstrating that juveniles distinguished and actively selected habitats using visual cues. However, they presented different responses in their occupancy patterns to increasing complexity of seagrass mimic habitats. While D. annularis responded positively to increases in complexity, S. tinca did not. These affinity variations between species suggest that differences in juvenile abundance between habitats found in previous field studies may be partially conditioned by active habitat choices. Understanding how different species respond to changes in seagrass structure is crucial for quantifying their nursery provision service. Moreover, this knowledge is essential to assess their potential vulnerability to seagrass loss in the context of environmental changes in the Mediterranean.
Complex network of trophic interactions in Burdwood Bank, a sub-Antarctic oceanic marine protected area
Authors: Marina TI , Schloss IR , Lovrich GA , Boy CC , Bruno DO , Capitanio FL , Delpiani SM , Díaz de Astarloa JM , Fraysse C , García Alonso VA , Raya Rey A , Schejter L , Spinelli ML , Tatián M , Urteaga D , Riccialdelli L
Published: April 2024

The world’s oceans designated under marine protection have increased recently. Most marine protected areas (MPAs) target vulnerable, keystone, charismatic, and/or endemic species. In the sub-Antarctic, ocean protection is associated with oceanic islands, except for the MPAs Namuncurá-Burdwood Bank I and II (MPA N-BB; ~53-55°S, ~56-62°W), which are associated with a submarine plateau and a southern deep slope, respectively. We present the first analysis of the predator-prey network for the MPA N-BB, applying a topological network approach to characterise the complexity and structure of the food web and to identify the species’ role. The MPA N-BB food web consists of 1788 interactions and 379 species, with a connectance of 0.01. Almost half of the consumers feed at more than one trophic level (0.48), and the network displays a small-world pattern (short path length, high clustering of compartments). This network pattern suggests that the ecosystem might be vulnerable to perturbations targeting highly connected species, although some properties might provide resilience and resistance, resulting in a rearranged structure that preserves its original functions. Several species arise as being important in trophic structure and functioning and response to perturbations. Generalist species, mainly fishes, play a crucial role in the bentho-pelagic coupling and should be considered as relevant energy transfer agents for the ecosystem. We argue that the diversity of species, including both the benthic and pelagic habitats, is responsible for securing the connectivity within the food web to withstand perturbations, thereby contributing to the structure and stability of the ecosystem.