bluuebunny/crossref_metadata_2025 huggingface dataset:
Changes in the expression of antimicrobial peptide genes in poultry under the influence of glyphosate and probiotic
Authors: Tyurina D. G. , Laptev G. Y. , Yildirim E. A. , Ilyina L. A. , Filippova V. A. , Brazhnik E. A. , Kalitkina K. A. , Ponomareva E. S. , Dubrovin A. V. , Novikova N. I. , Akhmatchin D. A. , Molotkov V. V. , Melikidi V. H. , Gorfunkel E. P.
Published: January 2023

Relevance. There is increasing information that glyphosates can have a range of adverse effects on animal, bird and human health, raising serious concerns about global feed and animal and poultry product safety.

   Methods. The experiments were carried out in the vivarium of OOO “BIOTROF+” on broilers of the Ross 308 cross. The birds were divided into 3 groups: 1st (control), which received a diet without additives, 2nd (experimental), which received a diet with the addition of glyphosate, 3rd (experimental), which received a diet with the addition of glyphosate and a strain of the microorganism Bacillus sp. GL-8. Analysis of the gene expression of the caecum of the intestines of broilers was carried out using quantitative PCR with reverse transcription. To analyze mRNA expression, specific primers for antimicrobial peptide genes were selected. Amplification reactions were performed using “SsoAdvanced™ Universal SYBR® Green Supermix” (“Bio-Rad”).

   Results showed that the residual amounts of glyphosates which are present at sterns of broilers influence an expression of genes of antimicrobic peptides AvBD1, AvBD2, AvBD4, AvBD6, CATH-2, NK-lysin, strengthening it. For example, in experimental group 2, there was an increase in gene expression of defensins AvBD1, AvBD2, AvBD4, AvBD6 by 21.9, 29.9, 35.1 and  33.5 times, respectively, compared to control group 1 (Р ≤ 0,001). A decrease (31 to 41%) in LEAP-2 gene expression when feed is contaminated with glyphosates may likely lead to a decrease in resistance to bacterial pathogens such as Salmonella enterica typhimurium, Streptococcus spp. and increased severity by the symptom of coccidiosis in poulty. The probiotic had a «leveling» effect on the expression of AvBD1, AvBD2, AvBD4 and AvBD6 defensin genes. This is likely due to the enhancement in the probiotic-modified gut microbiota of glyphosate metabolic opportunities, which may have acted as a physical barrier.
Obtaining and characterization of the spermatogenic cell culture of males from interspecific hybrids of domestic sheep and argal
Authors: Volkova L. A. , Volkova N. A.
Published: January 2023

Relevance. The creation of biological material cryobanks is one of the key methods for the conservation and maintenance of the biodiversity of animal genetic resources. The biomaterial widely used for preservation in cryobank conditions are mature germ cells of males – spermatozoa. As a promising alternative for these purposes is considered the use of testis stem cells – spermatogonia which makes it possible to select biomaterial from immature animals with a valuable genotype. The article presents data on obtaining a culture of spermatogonia of males of interspecific hybrids of domestic sheep with argali.   Methods. The object of research was spermatogenic cells of sheep's interspecific hybrids from the Romanov breed with argali. The testes of hybrid males served as a material for obtaining a spermatogenic cells culture. The conditions for isolating and maintaining spermatogonia in culture in vitro were optimized using histological, cytological, immunohistochemical and cultural methods.   Results. It has been established that the effectiveness of obtaining a spermatogenic cells culture, maximally enriched with spermatogonia, are affected by the age of the males from which the biomaterial is taken, the preliminary purification of spermatogonia from other types of spermatogenic and somatic testicular cells, the growth medium and the type of feeder layer used for the cultivation of spermatogonia. It is shown that the optimal age of males for the selection of biomaterial is the age period from birth to 4 months. During this period, the cells of the epitheliospermatogenic layer in the seminiferous tubules of the testes from hybrid males are mainly represented by one type of spermatogenic cells – spermatogonia (92–100 %). The maximum purification of spermatogonia from other types of cells is achieved by separating them according to adhesion. High intensity of growth and formation of spermatogonia colonies is observed when they are cultivated on the feeder layer formed by the primary culture of own Sertoli cells, as well as Sertoli cells from another rams. Under these conditions, the attachment of spermatogonia to the cells of the feeder layer is noted on the 1st – 2nd day of cultivation, the formation of colonies – on the 6th day of cultivation.
The influence of biotic factors on the parameters of the nucleolus
Authors: Iolchiev B. S. , Novgorodova I. P. , Prytkov Yu. A. , Klenovitsky P. M. , Khusnutdinova N. F. , Silantieva A. O. , Iolchiev R. B.
Published: January 2023

Relevance. The nucleolus regulates many aspects of cell physiology, including genome organization, stress response, aging, and lifespan. The number of visible nucleoli per cell varies depending on the cell cycle, cellular activity, or differentiation status.

   The aim of the study was to study the influence of abiotic factors on the parameters of animal nucleoli depending on their species (genus Ovis and genus Capra) and type of crossing (interspecific hybrids).   Materials and methods. The studies were carried out at the Federal Research Center for Animal Husbandry named after Academy Member L. K. Ernst. The object of the study were domestic sheep (Romanov breed) and its hybrids (½ Romanov sheep x ½ mouflon), as well as goats of the Karachay breed and their hybrids (¾ Karachay goat x ¼ caucasian tur). The material of the study was preparations obtained from venous blood and prepared according to the Havell – Blake method. For microscopy and visualization of preparations, a “Nikon Eclipse Ni” microscope equipped with a “DS-Qi2” digital video camera was used. The processing of photo- and videomaterials was carried out using the “NIS-Elements BR4.30” and “Image Scope 1.0” software.   Results. It has been established that in interspecific hybrids of goats (¾ Karachai goat x ¼ caucasian tur) the number of nucleolar-organizing regions (NOR) is 17 % more than in purebred individuals, while individual of interspecific hybrids of sheep (½ Romanov sheep x ½ mouflon) exceeded their purebred counterparts in this indicator by 47 %. The kurtosis and asymmetry of NOR in the population of purebred goats and their hybrids with the caucasian tur have the same directions. The results of the analysis of variance indicate that the effect of species on the size of the nucleoli in the studied populations is not statistically significant. The average value of the nucleolus diameter in representatives of the genus Capra was 6.17 ± 0.45 μm, genus Ovis – 6.63 ± 0.32 μm.
Results of evaluation of cotton samples (Gossypium hirsutum L.) under cultivation in the Astrakhan region
Authors: Myagkova E. G.
Published: January 2023

Relevance. For the intensification of cotton growing, an important component is availability of varieties adapted to specific growing conditions, capable of forming a crop in extreme climatic conditions and with optimal economically valuable characteristics. Therefore, the agrobiological study, evaluation and selection in the natural and climatic conditions of the Astrakhan region of promising and high-yielding cotton samples of various origins in order to involve the selected samples in further breeding work is relevant.   Methodology. The cotton collection of the All-Russian Institute of Plant Genetic Resources named after N. I. Vavilov served as the material for variety study. During the research work, the scheme of the selection process was built in accordance with the methodological instructions of N. P. Goncharov. The technique of laying and conducting field experience was according to the methodology of B. A. Dospekhov. The accounts, observations and measurements in the experiment were carried out in accordance with the G. G. Davidyan's methodological guidelines for the study of collection of spinning crops. The assessment of agroclimatic conditions for the growth and development of cotton was carried out by the calculation method. Interpretation of experimental data was carried out by common statistical methods, specifically, digital material was processed using variational statistics.   Results. As a result of variety study of cotton, samples capable to adapt to the zone of growth, as well as productive and with optimal economically valuable characteristics were identified. These qualities make it possible to use the selected samples for further breeding.
Evaluation of Multi-Literacy Education Program at The Community Learning Activity Center in Palangka Raya City
Authors: Sardimi Sardimi , Ariani Ety , Aghnaita Aghnaita
Published: January 2023

This is related to the quality of one's life so that it can open up public insight. The purpose of this study was to analyze the evaluation of the program on the aspects of context, input, process, and product of the multi-literacy education program at Learning Center (PKBM) Luthfillah, Palangka Raya. PKBM is an educational facility provided to provide non-formal education for citizens. Evaluation of the program that has been implemented uses the Context, Input, Process, and Product (CIPP) model by analyzing the components of the context, input, process, and product of the Multiliteracy Education program implemented. This research is a type of qualitative research. The research instruments used were observation, interviews, and documentation. The results of the research show: (1) in the context aspect, the program implemented has fulfilled the learning needs of the students, and the program objectives can be achieved as expected; (2) in the input aspect, educators and program organizers already have the expected competencies. It's just that for the initial abilities of students, the basic requirements for ownership of the Sukma have not been met; (3) in the process aspect, the learning strategies used are in accordance with the conditions of the students, namely andragogic, practical, and thematic strategies; (4) in the product aspect, students have graduated from the advanced literacy education program and have been able to apply the learning outcomes that have been obtained. However, the student's graduation certificate has not been received in the form of SUKMA-L.
Implementation of assessments in mathematics teacher learning during the covid-19 pandemic: A case study
Authors: Aziz Muhammad Bachtiar , Dwiyama Fajri
Published: January 2023

The aims of this study were to: (1) provide an overview of the implementation of assessments in mathematics learning carried out by mathematics teachers at MAN 2 Bone during the covid-19 pandemic, (2) find out the obstacles and obstacles for MAN 2 Bone teachers in carrying out mathematics assessments during the pandemic. covid-19 The research method used is descriptive analysis with quantitative and qualitative approaches. Data were obtained through a questionnaire/questionnaire and interviews. The results showed that the implementation of the assessment carried out by MAN 2 Bone teachers in learning mathematics during the pandemic period was quite well implemented. Even so, there are still teachers who experience problems in carrying out math assessments during the COVID-19 pandemic, starting from the difficulty of assessing students' conceptual understanding of mathematics to the decision to determine the final grade of the semester during the COVID-19 pandemic.
The Contribution of Organizational Culture in Schools to Improving Teacher Performance
Authors: Syaputra Adi , Santosa Achadi Budi
Published: January 2023

The role of organizational culture in improving school quality cannot be ignored, such as hard work habits, responsibility, relationships between school members, and efforts to improve quality. Meanwhile, teacher performance is very important for academic achievement. This study aims to reveal the extent of the role of organizational culture in schools in improving teacher performance. The approach used in this study is qualitative by using the narrative literature review method. The results of this study indicate that the role of organizational culture on teacher performance is very large. However, the implementation of organizational culture faces various obstacles, such as the socialization of regulations that have not been maximized, teachers who have not been disciplined, and in general, school residents who are comfortable with their previous habits. The influence of organizational culture on teacher performance and teacher motivation is quite significant. What needs to be anticipated are the implications because organizational culture that has been embedded for a long time sometimes becomes an obstacle to the change process.
Wasathiyah Quality Management: A Approach in Islamic Education Quality Management
Authors: Jayana Thoriq Aziz , Sujatnika Dadang Ahmad , Syarif Zainuddin , Noor Wahyudin
Published: January 2023

This paper explores the wasathiyah approach to quality management in Islamic educational institutions. The research uses library research methods to build an established scientific discourse. The study results show that in the management of Islamic educational institutions, which includes input, process, and output, it is necessary to apply the Wasathiyah approach. The implication of this research is to provide the principle of balance in managing the quality of Islamic education following the values in wasathiyah so that educational institutions can remain grounded in the values of balance (wasath). Currently, the secularization of Islamic educational institutions has led to the loss of the goals of Islamic education. Therefore, the Wasathiyah approach to managing education can maintain the institution's balance.
Implementation of Learning Management, Exploring Weaknesses and Strengths: A Case Study
Authors: Suryapermana Nana , Subekhan Moch , Rohman Moch Abdul
Published: January 2023

This study aims to analyze learning management, the strengths and weaknesses of the learning process, and student interest in learning. The research was conducted at Sirojul Atfal Cisoka High School. The research method uses descriptive qualitative and collecting data using observation, interviews, and documentation. The results showed that learning management was implemented through three stages: planning, implementation, and evaluation of learning. The integration of general subjects with religious subjects is an advantage of the learning process. However, the learning process that has not been appropriately managed makes it a weakness. This weakness causes students' low interest in learning, so their learning achievement decreases drastically.
Principal competency model development: Phenomenological design with coaching techniques in Sekolah Penggerak
Authors: Isnawan Muhamad Galang , Sudirman Sudirman
Published: January 2023

Sekolah Penggerak is one of the best episodes of the many Merdeka Belajar episodes. A separate curriculum known as Kurikulum Merdeka was prepared to support the program. The change in the principal’s competency model then became one of the unique phenomena in the curriculum change. The facts reveal that school principals cannot adapt quickly to this phenomenon, so this study aims to help school principals adapt more quickly to changes in competency models with coaching techniques. This study uses a phenomenological design because it wants to know the experiences that principals experience regarding the use of coaching techniques in responding to the phenomenon of changing competency models. The participants were three principals (51-55 years old) with 2-5 years of experience as principals. The instruments used are coaching questions developed in Sekolah Penggerak. Data is collected online through Google Meet and analyzed using qualitative data analysis techniques. The study results then revealed that coaching techniques could  to assist school principals in developing a model of school leadership competence, especially self-development and other people’s development, as well as learning leadership. This study also hopes that the principal will actively involve parents or guardians of students as mentors and learning resources.
Exploring INQF-Based Curriculum in English Education Study Programs: Investigation of Curriculum Implementation
Authors: Naibaho Lamhot , Silalahi Mardin
Published: January 2023

This study is about implementing the higher education curriculum based on the Indonesian National Qualification Framework (INQF). It was done at Universitas Kristen Indonesia strictly in the English Language Education Study Program. This study aims to find out how the implementation of the higher education curriculum based on INQF is. The study method used was a qualitative study with a descriptive design. The data of the study were collected through interviews. The instrument of the study was the interview sheet. The informants of the study were the head of the Quality Assurance Agency of Universitas Kristen Indonesia, the head of the Faculty Quality Assurance Agency, and the lecturers of the English Language Education Study Program. The data taken through interviews were analyzed descriptively through transcribing the interview data, data reduction, data display, and drawing conclusions. The result of the study is that the implementation of the learned curriculum is found to be through applicable, simple, and appropriate syllabus content, adding new information, and achieving goals and objectives, according to curriculum planning and quality standards. However, it requires improvement in certain parts of the curriculum implementation that some of the lecturers did not adjust the INQF-Based curriculum into the course they taught. Then it is concluded that although the INQF-Based curriculum has been structurally and well organized, it needs to be implemented by the whole lecturers in their learning and teaching. These findings suggest to the leadership of the University through the Quality Assurance Agency to control the implementation of the curriculum both at the Study Program level and at the lecturer level in carrying out the teaching and learning process.
Islamic Education Management based on Religious Moderation in the Industrial Revolution 4.0 Era
Authors: Khotijah Khotijah , Wahyudi Dedi , Wulandari Nawang , Ibrahim Faisal Mahmoud Adam
Published: January 2023

This paper aims to provide views on efforts to ground religious moderation education, primarily through managing Islamic education based on religious moderation in the 4.0 era. This study is a type of qualitative research with a library research approach. The data collection carried out in this article was obtained through reviewing or exploring various literature studies. The results show that an increase in Islamic education management can be done through technology and an increase in human resources who are aware of science and technology accompanied by a balance of the quality of faith and piety to have a solid spiritual, intellectual and moral foundation. In addition, the reform of the Islamic education system is in the aspects of paradigms, concepts, frameworks, and evaluations. The conclusion is that it is necessary to improve the management of Islamic education so that it develops better based on religious moderation, which can be used as a spiritual, moral, and intellectual laboratory.
The Perfective present in Lithuanian
Authors: Holvoet Axel , Daugavet Anna , Žeimantienė Vaiva
Published: January 2023

This article offers a picture of the Lithuanian perfective present, with particular emphasis on the treatment of habituality and genericity, the use of aspect forms in narrative text types, and peripheral constructionalised and often pragmatically specialised uses of perfective presents partly harking back to the actional differences underlying the aspect opposition in Baltic as well as in Slavonic. The introductory part of the article offers a general outline of the Lithuanian aspect system and briefly discusses the vexed question of the existence or non-existence of a grammatical category of aspect in Lithuanian. It is argued that, contrary to a widely held view, the Baltic languages have a grammatical category of aspect, though weakly grammaticalised.
Management Model of Kitab Kuning Reading Acceleration Program at Mambaul Ulum Islamic Boarding School, Bira Timur Sampang
Authors: Sayyi Ach. , Subhan Moh , Al-Manduriy Shahibul Muttaqien , Rofiqi Rofiqi
Published: January 2023

This research was motivated by the researchers' interest in the management of kitab kuning reading acceleration program at the Maktuba Mambaul Ulum Islamic boarding school, East Bira. The management carried out resulted in something extraordinary, where students who were still on average 7-12 years old managed to take part in the acceleration program for mastering the kitab kuning and master a series of other Islamic disciplines in just 2 years. If we relate to psychological theories, this is certainly a remarkable thing, considering that at their age in general they still live in the world of playgroup and education in the family. However, this does not make the management carried out ineffective, in fact this institution is able to create a pleasant learning atmosphere, and the target of this program can be achieved properly. This study focuses on the implementation of the kitab kuning reading acceleration program and its management in the pesantren. This research uses a qualitative approach and the type is descriptive research. As in the qualitative approach in general, the data collection techniques used are interviews, observation, and documentation. Analysis of the data used is by reduction, display, and verification. The research results show; first, the implementation of the acceleration program is by grouping students into 5 to 10 small groups with direct guidance for 24 hours by a musyrif. The two managements of kuning kuning reading acceleration program at the pesantren were carried out effectively and very well through planning, organizing, directing, and supervising carried out by this institution.
Kepemimpinan Pesantren untuk Menyiapkan Pemimpin Bangsa Bermoral dalam Menyongsong Bonus Demografi
Authors: Nur Azizah Fatiya , Dzakkiyah Siti
Published: January 2023

Dalam konteks pendidikan tujuan pendidikan diarahkan mampu untuk menghasilkan lulusan akademik yang profesional guna pengembangan ilmu pengetahuan serta peningkatan taraf hidup masyarakat. Pandangan masyarakat dalam memandang fungsi pendidikan pesantren sebagai lembaga pendidikan kedua, namun profil dari alumni pesantren dan kiprahnya dalam berbagai bidang kepemimpinan di masyarakat membuktikan bahwa pendidikan pesantren banyak memberikan kontribusi dalam pembangunan bangsa. Masyarakat mulai percaya bahwa pesantren sebagai lembaga tidak hanya sebagai pendidikan alternatif melainkan juga sebagai lembaga pendidikan utama untuk menghasilkan sumber daya manusia (SDM) yang baik dalam menghadapi bonus demografi ke depan, Bonus demografi merupakan peluang bagi Indonesia tetapi kalau tidak dipersiapkan dengan baik bisa menjadi tantangan bagi Indonesia. Jika seorang pemimpin dan semua elemen pemerintah mampu mempersiapkan tenaga kerja yang profesional dan mampu membuka lapangan kerja untuk menyerap seluruh angkatan kerja yang tersedia. Namun sebalikanya jika pemerintah tidak mampu melakukannya yang terjadi di Indonesia adalah negara yang banjir pengangguran di masa depan. Tantangan terbesar dalam mempersiapkan bonus demografi adalah bagaimana pemimpin dan seluruh jajarannya mampu mengelola penduduk berusia produktif yang begitu banyak agar produktif dari berbagai bidang. Karena apabila hanya produktif dari segi usia saja tapi tidak produktif dalam segi ekonomi, pendidikan dan sebagainya justru akan menjadi petaka bagi negara. Selain menyebabkan angka pengangguran yang melonjak hal ini juga akan berdampak negatif bagi kehidupan sosial. Tujuan penelitian ini merupakan upaya untuk menjelaskan konsep Implikasi kepemimpinan pesantren dalam menyiapkan pemimpin bangsa yang bermoral khususnya yang berasal dari lulusan pesantren akan mumpuni dalam menghadapi era bonus demografi kedepan dengan mempunyai keahlian dibidang agama, bidang pengetahuan  umum dan keterampilan calon pemimpin bangsa yang bermoral. Dalam penelitian ini menggunakan meode Studi kepustakaan dengan pendekatan kualitatif.

Kata Kunci: Kepemimpinan pesantren, pemimpin bangsa bermoral, bonus demografi
Sejarah dan Perbandingan Pendidikan Multikultural Di Negara Turki dan Belanda
Authors: Suprapno Suprapno , Hifdzil Haq Ahmad , Noer Aly Hery , Zulkarnain Zulkarnain , Ismail Ismail
Published: January 2023

Tujuan penelitian ini adalah untuk mengungkap dan mendiskripsikan tentang sejarah dan perkembangan serta perbandingan penerapan ideologi multikulturalisme dalam setiap kebijakan pemerintah Turki dan Belanda. Terutama tentang sejarah dan perbandingan sistem pendidikan multikultural di Turki dan Belanda. Metode penelitian yang digunakan adalah metode kualitatif berbasis historis, mengingat data yang akan diteliti merupakan kejadian yang telah terjadi. Pendekatan penelitian historis ini dilakukan dengan cara menelaah data kepustakaan (library reseach). Teknik analisis yang digunakan dalam penelitian ini adalah analisis deskriptif kualitatif dengan mendiskusikan data hasil bacaan sumber primer dengan data hasil bacaan sumber sekunder. Hasil penelitian menunjukkan bahwa dua negara ini sama-sama menerapkan ideologi multikulturalisme dan penerapan pendidikan multikultural, hal tersebut dilakukan karena kedua negara ini menjadi tempat pelarian para imigran yang memiliki latar belakang yang berbeda-beda, namun demikian dalam pengaplikasin sistem pendidikan multikultural kedua negara ini dalam penerapannya ditemukan adanya perbedaan, hal tersebut disebabkan oleh perbedaan mayoritas agama yang ada di Turki dan Belanda. Perbedaan dalam penerapan sistem pendidikan multikultural meliputi kebebasan orang tua dalam memilih dan luar biasa dalam menentukan sekolah negeri maupun sekolah denominasi masing-masing di Turki dan Belanda,  peran penting dan sangat sentral dari pemerintah Turki nampak jelas dalam mengkonsep, melaksanakan, dan mengevaluasi kurikulum yang memuat nilai multikulturalisme dan buku-buku teks, dibandingkan dengan kebijakan multikulturalisme yang ada di Belanda terlihat marjinal dan hanya melakukan penyesuaian dan pemeriksaan bahan ajar yang memuat ideologi multikulturalisme.
Kontribusi Zakat dalam Pengembangan Pendidikan di Indonesia
Authors: Muzammil Achmad , Nasrullah Alfan
Published: January 2023

Pendistribusian dana zakat hendaknya tidak hanya diarahkan kepada kebutuhan mustahiq yang bersifat konsumtif, melainkan dapat didistribusiakan dalam bidang pendidikan sebagai wujud investasi sumber daya manusia di masa depan. Dana zakat dapat membatu banyak hal dalam pengembangan dan penguatan kualitas dan mutu pendidikan di Indonesia sehingga pengaolokasinan dana tersebut sangat penting untuk dilakukan. Penelitian ini bertujuan untuk menungkap kontribusi zakat dalam pengembangan pendidikan di Indonesia. Motode penelitian yang dilakukan adalah pendekatan kualitatif dengan jenis penelitian library research sehingga data-data yang dihimpun dan dianalisis yaitu data yang diperoleh dari kepustakaan seperti buku, artikel ilmiyah dan lain-lain. Hasil penelitian ini menujukkan bahwa zakat sebagai sebuah sistem dapat dialokasikan dalam bidang pendidikan, hal ini tentu merupakan tindakan produktif sebagai upaya menyiapkan sumber daya manusia yang kuat dan kompetitif di masa depan. Terdapat beberapa cara yang dapat dilakukan dalam pengembangan pendidikan melalui zakat meliputi: 1) Memberikan beasiswa kepda kaum dhuafa’ yang tidak mampu untuk membiayai sekolah. 2) Memberikan program pembiayaan pendidikan dengan menyalurkan bantuan sarana pra sarana kapada lembaga pendidikan yang mambutuhkan. Pemberdayaan masyarakat melalui pendidikan menjadi suatu hal yang harus digerakkan bersama, hal ini menjadi isyarat bahwa pendidikan merupakan solusi terbaik dalam mengentaskan kemiskinan. Pembentukan SDM yang unggul merukan tugas utama pendidikan melalui penanaman nilai-nilai yang dapat mengemangkan potensi hidup mereka. Potensi yang dimaksud adalah potensi spritual, intelektual, sosial, kultural, dan potensi yang lain yang melakat pada seorang individu
Georg Heym. El poeta que vio a Berlín en llamas en 1911.
Authors:   Universidad Autónoma de San Luis Potosí, Navarro Fuentes Carlos Alberto
Published: January 2023

El ensayo tiene que objetivo principal ofrecer un panorama general sobre algunos de los poemas más representativos del poeta alemán expresionista Georg Heym (1887-1912), quien vivió en Alemania a finales del siglo XIX y principios del XX, no alcanzando ni siquiera los 30 años de vida. No obstante, el dato anterior, su legado poético fue lo suficientemente rico y significativo como para considerársele uno de los más grandes poetas en lengua alemana de la historia de sus letras que, además visionó con gran precisión, la hecatombe que se cernía sobre Europa y se haría realidad durante la primera mitad del siglo XX. Por lo anterior, el texto presenta precisamente algunos poemas que dan cuenta en su contenido de imágenes y escenas que estarían por venir, es decir, antes de que se convirtieran en hechos factuales como parte del período histórico e imaginario sociocultural de la época (Zeitgeist) en el que tanto el lenguaje como la literatura se vieron afectados e impactados por la atmósfera que impregnaran el nacionalismo y el fascismo. La manera en la cual procede la exposición de este ensayo es simplemente poniendo a los ojos del lector, algunos de estos poemas mencionados para su goce y conocimiento de lo que se afirma como testimonio en cuestión a partir de su lectura.
En las fronteras de un cuento de Clarice Lispector.
Authors:   Departamento de Estudios Literarios / Universidad de Guadalajara, Gómez Bocanegra Jorge Martín
Published: January 2023

Ingresar al mundo textual de “El huevo y la gallina” es como aventurarse a los abismos del pensamiento de Clarice Lispector. Este trabajo es una aventura posible en ese abismo extraño que conforma el lenguaje de dicha autora. Se trata de un lenguaje impulsado por la mirada fenomenológica, y por esto mismo, una mirada inquietante que nos hace cobrar conciencia de lo que significa estar viendo un objeto que aparece de una forma cotidiana.
Análisis de recursos digitales para la integración de la realidad aumentada en la educación.
Authors:   Departamento de Lenguas Modernas/ Universidad de Guadalajara, Trejo González Hugo
Published: January 2023

El objetivo principal de este trabajo consiste en contribuir a la comprensión de las posibilidades educativas mediante el uso de herramientas digitales de Realidad Aumentada (RA). Para lograr dicho objetivo, realizamos un análisis de la disponibilidad actual en el ámbito a fin de obtener información de algunas herramientas que permitan integrar la Realidad Aumentada en contextos educativos. A partir de 19 resultados herramientas de RA, seleccionamos 4 recursos y realizamos un análisis profundo de sus características principales, posibilidades didácticas y una evaluación que considera criterios generales de Usabilidad. Este análisis nos permitió obtener información precisa sobre el funcionamiento de los medios digitales para su posible integración en el aula o para su estudio posterior en otras investigaciones acerca de la innovación con la inclusión de la Realidad Aumentada. Mediante la revisión cualitativa analizamos algunas de las funciones tecnológicas para la inclusión de estas herramientas en contextos educativos y obtuvimos información precisa sobre el nivel de implicación de la RA. En resumen, distinguimos 2 recursos que posibilitan la inclusión de la RA manera simplificada o limitada y 2 plataformas digitales con un mayor número de posibilidades para el profesorado más experimentado.
Perspectiva docente sobre las clases en línea ante la pandemia por COVID-19 en Sonora, México.
Authors:   Instituto Tecnológico de Sonora, Gómez Espinosa Kimberly Denise , Cruz Pérez Oscar ,   Universidad de Ciencias y Artes de Chiapas, García Lara Germán Alejandro ,   Universidad de Ciencias y Artes de Chiapas, Esteban Silvestre Hildebertha ,   Instituto de Intervención Psicosocial, Ocaña Zúñiga Jesús ,   Universidad de Ciencias y Artes de Chiapas
Published: January 2023

En esta investigación de corte cualitativo, se describe la perspectiva de docentes de nivel primaria acerca de la modalidad de clases en línea implementada ante la pandemia por COVID-19 en Cajeme, Sonora, México. Se realizaron 18 entrevistas a profundidad con el profesorado de diversas escuelas públicas en el periodo de enero a junio de 2021. Los resultados indican los desafíos que afrontan los docentes en términos de limitada comunicación con los padres de familia, una mayor cantidad de trabajo administrativo y una deficiente estructura tecnológica. Se concluye que los docentes emplearon distintas estrategias para responder a estas dificultades en el trabajo escolar.
Theodor W. Adorno: resistencia y briznas de vida moral.
Authors:   Departamento de Filosofía. Universidad de Guadalajara, Hernández López Dinora
Published: January 2023

El propósito de este artículo es analizar algunos fragmentos de Mínima moralia, en el marco de las reflexiones de filosofía moral de Theodor W. Adorno. Considero que las nociones de libertad negativa y melancolía hacen visible el ingrediente crítico-negativo del texto, con el cual Adorno analiza la acción moral, permitiendo escapar de las lecturas positivas y edificantes. El trabajo está conformado por cuatro breves apartados: en el primer de ellos, realizo una caracterización mínima de la filosofía moral de Adorno; en el segundo, analizo las condiciones objetivas que limitan la emergencia de un sujeto moral en la sociedad moderno-capitalista; en el tercer apartado, trato la noción de resistencia; finalmente, la última parte contiene el análisis de los fragmentos.
¿Adquieren los aprendices sinohablantes los marcadores de discurso en el nivel establecido por el PCIC?: Posiciones y combinatorias.
Authors:   Universidad Complutense de Madrid, Yang Qin
Published: January 2023

El objetivo de este trabajo es describir el uso de los marcadores de discurso por parte de los aprendices sinohablantes de español. En concreto, nos interesa describir no solo los niveles en los que se adquieren estas unidades y las funciones que cumplen, sino también otras variables a las que se ha atendido en menor medida: la posición oracional que ocupan los marcadores en las producciones de los aprendices y los elementos léxicos con los que suelen combinarse. Para ello, se propone un análisis de corpus de aprendices de los marcadores también, pero, por eso, porque y después. Los resultados muestran que los aprendices sinohablantes utilizan estos marcadores con una gran libertad posicional y que su combinatoria es bastante menor en comparación con las habituales en las producciones nativas.
La enseñanza y el aprendizaje del francés en el escenario bajacaliforniano.
Authors:   Universidad Autónoma de Baja California, Fong Flores Jesús Eduardo
Published: January 2023

Este artículo sugiere un acercamiento al escenario de la formación del profesorado y de la investigación en el área del francés como lengua extranjera (FLE) desde lo lingüístico, didáctico y pedagógico. Por consiguiente, a lo largo de esta investigación se sugieren diversos desafíos formativos que, como formadores de profesores, se deben reflexionar al momento de plantear una especialización en el área de FLE. Se identifica que el aprendizaje de la lengua francófona es una constante en el ambiente educativo, pero, a su vez, requerirá de un planteamiento desde la formación, la investigación y el fomento a la lengua y su cultura. Esta investigación se desarrolla a partir del enfoque cualitativo y comprende tres etapas: la primera la exploración de un escenario formativo respecto a la lengua en la Facultad de Idiomas de la Universidad Autónoma de Baja California; la segunda un entendimiento de las necesidades formativas a través de una entrevista semi estructurada; y la tercera una documentación sobre investigaciones en el área de francés en nuestra facultad. La discusión de los datos sugiere que es necesaria una revaloración académica del escenario respecto a la especialización en el área de FLE en función a la formación del enseñante y la investigación.
Una breve aproximación a la filosofía del lenguaje de Saul Kripke a partir de Naming and Necessity.
Authors:   IES Rosalía de Castro, Villamor Iglesias Alejandro
Published: January 2023

El presente artículo tiene como objetivo principal proporcionar al lector una breve aproximación a la filosofía del lenguaje de Saul Kripke. La utilidad de esta empresa es en esencia aportar un texto básico en español sobre los conceptos fundamentales del mismo. Lejos de confundir con una miríada de fuentes secundarias innecesarias para los mencionados fines, este trabajo se limita a analizar casi exclusivamente las tesis kripkeanas a partir de su texto más importante, Naming and Necessity. Sin rehuir el rigor académico, el artículo aporta una orientación inicial para toda persona interesada en la filosofía de Kripke.
La psicosis como mecanismo involuntario de interpretación de la realidad en el protagonista de El túnel.
Authors:   Universidad Nacional Mayor de San Marcos, Delgado del Águila Jesús Miguel
Published: January 2023

Este trabajo tiene la finalidad de fundamentar las razones que conducen al personaje Juan Pablo Castel de la novela de Ernesto Sabato El túnel (1948) a la psicosis, entendida esta como una estrategia involuntaria para interpretar la realidad y actuar en función de la cosmovisión que le genera. Para explicar esa adopción identitaria, retomo la taxonomía elaborada por Donald Shaw con respecto al contexto influyente del boom latinoamericano (que repercute negativamente en la psicología social) y la epistemología psicoanalítica de Jacques Lacan al hacer referencia a nociones afines que configuran al protagonista como una entidad desligada del mundo real y que cuenta con un potencial saber infundado hacia la destrucción del ser.
Las letras mexicanas y su moderna lexicografía en Dante Medina.
Authors:   Departamento de Filología Hispánica / Universidad de Huelva, Ruiz Llamas Sandra
Published: January 2023

A partir del siglo XX la Literatura Hispanoamericana destacó por su notable y original narrativa. Este ensayo de carácter lingüístico analiza la obra innovadora en el campo de la renovación de la lengua del escritor mexicano Dante Medina. El estudio que presentamos tiene un enfoque romanista al tratarse de un escritor que trabaja con distintas lenguas: el español, el italiano y el francés. Sus textos en la mayoría tienen una gran riqueza lingüística que evitan el pensamiento tradicional, provocando una nueva edición y escritura en sus textos, los cuales abarcan intuiciones, convicciones, innovaciones, y emociones. Dante Medina es un delicado artista del lenguaje. En su práctica lexicográfica, propone una edición distinta de la narrativa en la que en su discurso también recrea personajes, acorde al cambio de la presentación de los párrafos. El autor juego y explora nuevos géneros literarios, que, aunque retorcidos, enriquece las unidades narratológicas latinoamericanas. Desde la perspectiva de la lingüística, es posible analizar la narrativa que Dante Medina ha engendrado en los últimos cincuenta años, uno de los modelos estructurales e iniciadores de la invención del lenguaje en el siglo XXI en Jalisco. Su narrativa, aunque sea de ficción, conserva sus propias reglas, creando sistemas semióticos que sirven precisamente para seguir fecundando nuevos niveles de sentido en el texto. Su obra permite enriquecer la Lengua Española y, con ello, abrir otras posibilidades de vanguardia fantástica en el siglo XXI.
The Existence of Mercury Nanoparticles
Authors: Ghoshdastidar Avik , Ariya Parisa A.
Published: January 2023

In this work, we show that previously unknown mercury-containing nanoparticles exist in the air using high-resolution scanning transmission  electron microscopy imaging (HR-STEM). Deploying an urban-air feld campaign near a mercury point  source, we provide further evidence for mercury nanoparticles and determine the extent to which  these particles contain two long suspected forms of oxidized mercury (mercuric bromide and mercuric  chloride) using mercury mass spectrometry (Hg-MS). Using optical particle sizers, we also conclude  that the conventional method of measuring gaseous oxidized mercury worldwide can trap up to 95%  of nanoparticulate mercuric halides leading to erroneous measurements. Finally, we estimate airborne  mercury aerosols may contribute to half of the oxidized mercury measured in wintertime Montréal  urban air using Hg-MS. These emerging mercury-containing nanoparticle contaminants will infuence  mercury deposition, speciation and other atmospheric and aquatic biogeochemical mercury processes  including the bioavailability of oxidized mercury to biota and its transformation to neurotoxic organic  mercury. 
Must Keep Going
Authors: Metersky Kateryna
Published: January 2023

Poem written for special issue called "Learning from one another in medical encounters."
The need for clarification of terminology and labels in interprofessional care: A commentary
Authors: Metersky Kateryna , Axenciuc Rostislav , Mitchell Emily , Nyathi Sifelipilu
Published: January 2023

Background: The current healthcare environment is filled with numerous team caring models, which are often used interchangeably, but ultimately mean different levels of collaboration among HCPs, and between HCPs and patients: multiprofessional collaboration, transprofessional collaboration, and interprofessional patient-centered collaborative (IPCC) care. Furthermore, the labels for these care models are not patient-friendly, portraying that only HCP ‘professionals’ comprise the team membership. Clarity is required around the terminology and labeling of these caring models to ensure enhanced patient involvement within interprofessional teams. Discussion: The definitions of the three team care models are provided with an explanation of how these models of care connect to the 55year-old patient’s case and impact on the relationship between HCPs and patient. Conclusion: While IPCC care is considered as the gold standard for the collaboration between a variety of HCP professional groups and the patient, work needs to be done on the label applied to this caring model. Future research should explore, from patients’ perspectives, the labels used in IPCC care and propose an alternative title that is more inclusive of patients as team members. 
Proximity Profiling of the CFTR Interaction Landscape in Response to Orkambi
Authors: Iazzi Melissa , Astori Audrey , St-Germain Jonathan , Raught Brian , Gupta Gagan
Published: January 2023

Deletion of phenylalanine 508 ( increment F508) of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) anion channel protein is the leading cause of Cystic Fibrosis (CF). Here, we report the analysis of CFTR and increment F508-CFTR interactomes using BioID (proximity-dependent biotin identification), a technique that can also detect transient associations. We identified 474 high-confidence CFTR proximity-interactors, 57 of which have been previously validated, with the remainder representing novel interaction space. The increment F508 interactome, comprising 626 proximity-interactors was markedly different from its wild type counterpart, with numerous alterations in protein associations categorized in membrane trafficking and cellular stress functions. Furthermore, analysis of the increment F508 interactome in cells treated with Orkambi identified several interactions that were altered as a result of this drug therapy. We examined two candidate CFTR proximity interactors, VAPB and NOS1AP, in functional assays designed to assess surface delivery and overall chloride efflux. VAPB depletion impacted both CFTR surface delivery and chloride efflux, whereas NOS1AP depletion only affected the latter. The wild type and increment F508-CFTR interactomes represent rich datasets that could be further mined to reveal additional candidates for the functional rescue of increment F508-CFTR. 
Forced Entertainment? Gamified Surveillance in Theatre Conspiracy’s Foreign Radical
Authors: Jones Matt
Published: January 2023

The nature of surveillance is changing. It is becoming gamified. This article charts a shift in thinking about surveillance culture, from the panopticon models advanced by Jeremy Bentham and Michel Foucault to current analyses of the increasingly participatory and gamified models of surveillance in the age of big data. That shift is played out literally in Theatre Conspiracy’s immersive play Foreign Radical, in which participants are led through a game environment in which they reveal aspects of their online behaviour and judge each other in a way that replicates the kinds of social sorting that take place in both social media and surveillance. The game leads them to deliberate on the case of an Iranian-Canadian man named Hesam, who stands accused of terrorism. As the case against Hesam comes to rest increasingly on his Middle Eastern and Islamic identity, the show reveals the role that racism and Islamophobia come to play in the interpretation of surveillance data. Although surveillance operates on a seemingly empirical basis, the stories it tells about people nevertheless remain fictions, assembled from statistical probability and speculation. In this way, surveillance adds to the sense that we live in a post-truth society. 
N,1-Bis(4-chloro-2-methylbenzyl)-3- methyl-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxamide
Authors: Porosa Lukasz , Viirre Russell , Lough Alan J.
Published: January 2023

 In the title molecule, C27H26Cl2N2O2, the chloro-substituted benzene rings make dihedral angles of 83.29 (9) and 80.81 (9) with the benzene ring of the tetrahydroquinoline group. The dihedral angle formed by the two chloro-substituted benzene rings is 40.87 (12). The six-membered N-containing ring is in a half-chair conformation. In the crystal structure, intermolecular N—HO hydrogen bonds link molecules into centrosymmetric dimers. 
Mentally Ill and Cute as Hell: Menhera Girls and Portrayals of Self-Injury in Japanese Popular Culture
Authors: Seko Yukari , Kikuchi Minako
Published: January 2023

Over the last few decades, self-injury has gained wide visibility in Japanese popular culture from manga (graphic novel), anime (animation), to digital games and fashion. Among the most conspicuous is the emergence of menhera (a portmanteau of “mental health-er”) girls, female characters who exhibit unstable emotionality, obsessive love, and stereotypical self-injurious behaviors such as wrist cutting. Tracing the expansion of this popular cultural slang since 2000, this conceptual article explores three narrative tropes of menhera—the sad girl, the mad woman, and the cutie. Within these menhera narratives, self-injury functions as a self-sufficient signifier of female vulnerability, monstrosity, and desire for agency. These menhera tropes, each with their unique interpretation of self-injury, have evolved symbiotically with traditional gender norms in Japan, while destabilizing long-standing undesirability of sick/detracted female bodies. The menhera narrative tropes mobilize cultural discourses about female madness and subsequently feed back into the social imaginaries, offering those who self-injure symbolic resources for self-interpretation. We argue that popular cultural narratives of self-injury like menhera may exert as powerful an influence as clinical discourses on the way we interpret, make sense of, and experience self-injury. Being attentive to cultural representations of self-injury thus can help clinicians move toward compassionate clinical practice beyond the medical paradigm.