bluuebunny/crossref_metadata_2025 huggingface dataset:
Minority Influence and Degrowth-Oriented Pro-environmental Conflict: When Emotions Betray Our Attachment to the Social Dominant Paradigm
Authors: Avery Robert A. T. , Butera Fabrizio
Published: June 2022

If today the anthropogenic origin of climate change gathers almost total scientific consensus, human pro-environmental action is not changing with sufficient impact to keep global warming within the 1.5° limit. Environmental psychology has traditionally focused on the underlying barriers towards more pro-environmental behaviours. Emotions—like fear or anger—may act as such barriers especially in case of radical change (e.g., degrowth). While minority influence has been extensively applied to understand societal change, it has rarely been applied to understand the emotional responses that may hinder counter-normative pro-environmental messages. However, past literature on emotions shows that, in challenging situations—the likes of radical minority conflict—people will tend to use their emotional reaction to maintain societal status quo. Two studies investigated how participants emotionally react towards a counter-normative pro-environmental minority message (advocating degrowth). A qualitative (thematic analyses) and a quantitative (emotional self-report paradigm) studies showed that participants report emotions that allow them to realign themselves with the cultural backdrop of the social dominant paradigm (growth), thus resisting change. Specifically, although all participants tend to demonstrate higher proportions of control-oriented emotions, men do so more. These effects, as well as questions of cultural and ideological dominance, are discussed considering barriers towards pro-environmentalism.
Investigating the Effects of Capital Structure and Corporate Governance on Firm Performance: An Analysis of the Sugar Industry
Authors: Shahzad Akmal , Zulfiqar Bushra , Hassan Mehmood ul , Mathkur Naif Mansour , Ahmed Irfan
Published: June 2022

The objective of this paper is to investigate the impact of capital structure and corporate governance on firm performance. To test the hypothesis of study, data was collected from annual reports of sugar sector companies listed in PSX. This study data covers from 2015 to 2020. The results of study showed that both proxies of capital structure, i.e., D/A and D/E negatively influence the company performance. Whereas two out of three proxies of corporate governance, i.e., board size and chairman/CEO duality negatively indicate association with company performance while audit committee size has a positive impact on the company performance.
The Effect of Sports Performance Entrepreneurial Project by Entrepreneurial Spirit
Authors: Song Shuxiong
Published: June 2022

This study aims to analyze the effect of entrepreneurship on the growth of entrepreneurial enterprise projects, so that entrepreneurial projects can improve entrepreneurial performance, promote social and economic development, and improve resource allocation. Firstly, entrepreneurship is explored to analyze the role in the growth of entrepreneurial enterprise projects. The entrepreneurial essence requirements based on entrepreneurship provide a theoretical basis for sports performance entrepreneurship. Secondly, the idea and process of sports performance entrepreneurship are described. A growth model of sports performance entrepreneurship based on entrepreneurship is established. Finally, the entrepreneurs who started sports performances are considered to investigate the enterprises participating in a sports competition performance. The influence of six elements of entrepreneurship on the progress and performance of sports performance entrepreneurial projects is analyzed. The results show that the spirit of risk-taking, need for achievement, and professionalism in entrepreneurship have the highest consistency, all above 0.90. It shows that entrepreneurship can promote the sports performance entrepreneurship project, and the subjects have a high entrepreneurial spirit. The adventurous spirit has more than half of the coverage of sports performance entrepreneurial projects. The coverage rate of knowledge literacy, innovative spirit, advanced action, achievement needs, and professionalism in sports performance entrepreneurial projects are all about 0.43. Innovation, risk-taking, and creativity can boost the performance of sports performance entrepreneurial projects. Enterprise size has little influence on sports performance. These conclusions have reference significance for the impact of sports entrepreneurial project performance.
Effects of Time Constraints and Goal Setting on Basketball Shooting
Authors: Kostrna Jason
Published: June 2022

In sport, numerous high-pressure situations require athletes to perform motor tasks under temporally constrained circumstances. The present study investigated the effects of time constraints on anxiety, attention, performance, and mechanics of basketball free-throw shooting. Additionally, the potential benefits of goal setting were examined in relation to performance in time-constrained situations. Forty undergraduates (n = 10 elite basketball players, n = 15 experienced, n = 15 inexperienced) attempted free throws in timed, untimed, and goal-oriented conditions. In the timed condition, participants attempted to make as many field goals as possible in 30 s. In the untimed condition, participants attempted the same number of field goals as they did in the timed trial but without a time constraint. In the goal-oriented condition, participants attempted to surpass their highest number of successful field goals while once again under a 30-s time constraint. Participants in the timed condition had the worst field goal percentage (M = 45.20%, SD = 21.96%), while the untimed (M = 55.76%, SD = 21.12%, p < 0.05, d = 0.49) and goal-oriented conditions (M = 55.79%, SD = 22.92%, p < 0.05, d = 0.47) had similar field goal percentages. In addition, joint consistency in the elbow and knee increased during the untimed condition compared to both timed and goal-oriented conditions. Results indicate that a goal-oriented focus may prevent performance declines present in time-constrained situations.
Nuclear Norm Regularized Deep Neural Network for EEG-Based Emotion Recognition
Authors: Liang Shuang , Yin Mingbo , Huang Yecheng , Dai Xiubin , Wang Qiong
Published: June 2022

Electroencephalography (EEG) based emotion recognition enables machines to perceive users' affective states, which has attracted increasing attention. However, most of the current emotion recognition methods neglect the structural information among different brain regions, which can lead to the incorrect learning of high-level EEG feature representation. To mitigate possible performance degradation, we propose a novel nuclear norm regularized deep neural network framework (NRDNN) that can capture the structural information among different brain regions in EEG decoding. The proposed NRDNN first utilizes deep neural networks to learn high-level feature representations of multiple brain regions, respectively. Then, a set of weights indicating the contributions of each brain region can be automatically learned using a region-attention layer. Subsequently, the weighted feature representations of multiple brain regions are stacked into a feature matrix, and the nuclear norm regularization is adopted to learn the structural information within the feature matrix. The proposed NRDNN method can learn the high-level representations of EEG signals within multiple brain regions, and the contributions of them can be automatically adjusted by assigning a set of weights. Besides, the structural information among multiple brain regions can be captured in the learning procedure. Finally, the proposed NRDNN can perform in an efficient end-to-end manner. We conducted extensive experiments on publicly available emotion EEG dataset to evaluate the effectiveness of the proposed NRDNN. Experimental results demonstrated that the proposed NRDNN can achieve state-of-the-art performance by leveraging the structural information.
The Effect of Brand Personality on Electronic Word-of-Mouth: Mediation of Brand Love and Moderated Mediation of Brand Experience Sharing
Authors: Liu Manlin , Yan Jinzhe
Published: June 2022

The knowledge payment industry will rapidly attract many enterprises that provide knowledge services. This study investigates the interrelationship between brand personality, brand love, and electronic word-of-mouth in the context of knowledge payment. Moreover, this study explored the brand experience sharing boundary condition by adopting a survey. Firstly, the main research results show that brand personality has a significant positive impact on brand love. Secondly, brand love also has a significant positive influence on electronic word-of-mouth. Thirdly, brand experience sharing plays a positive role in regulating brand love and electronic word-of-mouth. This research promotes e-marketing by focusing on brand personality, brand love, e-word of mouth, and other perspectives to improve business operations, user experience, and engagement, providing dedicated products or services to the customer base for profit. As an emerging market, knowledge payment will attract the participation of many knowledge service enterprises.
Pointers to Interventions for Promoting COVID-19 Protective Measures in Tourism: A Modelling Approach Using Domain-Specific Risk-Taking Scale, Theory of Planned Behaviour, and Health Belief Model
Authors: Ohnmacht Timo , Hüsser Andreas Philippe , Thao Vu Thi
Published: June 2022

Based on the factors of the Theory of Planned Behaviour (TPB), the Health Belief Model (HBM), and the DOSPERT scale, used to measure general risk-taking behaviour, a combined model has been developed for investigating tourists’ intentions to implement protective measures against the coronavirus disease 2019 (COVID-19). The purpose of the study is to formulate a model that Swiss tourism practitioners can use to understand tourists’ decision-making regarding the acceptance and proper implementation of non-pharmaceutical interventions (NPIs). A large-scale cross-sectional population study that is representative for the Swiss population has been designed to validate the model (N = 1,683; 39% response rate). In our empirical investigation, a simple regression analysis is used to detect significant factors and their strength. Our empirical findings show that the significant effects can be ordered regarding descending effect size from severity (HBM), attitude (TPB), perceived behavioural control (TPB), subjective norm (TPB), self-efficacy (HBM), and perceived barriers (HBM) to susceptibility (HBM). Based on this information, intervention strategies and corresponding protective measures were linked to the social-psychological factors based on an expert workshop. Low-cost interventions for tourists (less time, less money, and more comfort), such as the free provision of accessories (free mask and sanitizers) or free testing (at cable cars), can increase the perceived behavioural control and lower the perceived barriers and thus increase the acceptance of this protective measure.
Socioeconomic Status Association With Dependency From Objective and Subjective Assessments: A Cross-Sectional Study
Authors: Pan YiYang , Aierken Ayizuhere , Ding XiWen , Chen Yuan , Li Ying
Published: June 2022

Background

The effect of socioeconomic status (SES) on dependency is still complex and not fully clear. The purposes of this study are to assess the association between SES and dependency personality disorder (DPD) using both objective and subjective assessments.

Methods

A cross-sectional study was conducted in 27 locations in China among 1,276 general residents aged 60 years and above through a complex multistage sampling design. Data were collected using a questionnaire by well-trained investigators through face-to-face interviews. The DPD was assessed using a standardized Chinese version of the Minnesota Multiphasic Personality Inventory-II scale. Objective SES was assessed by the combination of education levels, individual income, preretirement occupation, and medical insurance. Subjective SES was measured using the MacArthur Scale. The logistic regression analysis was used to evaluate the association between objective SES and DPD. Analysis of covariance was conducted to compare the mean of DPD scores in different levels of SES.

Results

The results of the chi-squared test showed that the levels of objective SES were associated with DPD, depression, social resources, and region. The logistic regression analysis showed a significant negative association between the levels of objective SES and DPD. The odds ratio was 1.84 (95% confidence interval, 1.07–3.18) after adjusting for important confounding factors. The analysis of covariance showed differences in the mean of DPD scores among different groups defined by different levels of SES.

Conclusion

The levels of SES were negatively associated with DPD, and subjective SES had a stronger association with DPD than objective SES. The effect of subjective SES on DPD is possibly associated with the perception of position in the social hierarchy.
Early Autism Intervention Components Deliverable by Non-specialists in Low- and Middle-Income Countries: A Scoping Review
Authors: Naithani Lavangi , Goldie Caitlin , Kaur Abhipreet , Butter Charlotte , Lakhera Shweta , Leadbitter Kathy , Divan Gauri
Published: June 2022

Introduction

The past decade has seen key advances in early intervention for autistic children in high-income countries, with most evidence based on specialist delivery of interventions. The care gap seen in low- and middle-income countries (LMIC) remains close to 100%. A key challenge in addressing this care gap concerns the paucity of specialists available to deliver services. Task-sharing provides an important potential solution; there is a need to identify interventions that are suitable for scaled-up delivery through task-sharing in low-resourced settings. We aimed to conduct a scoping review to identify studies which reported autism intervention delivered by non-specialists within LMIC and, using established frameworks, specify intervention components with evidence of successful non-specialist delivery.

Methods

A scoping literature search, conducted within four databases, generated 2,535 articles. Duplicates were removed, followed by screening of titles and abstracts, with 10% double-rated for reliability. 50 full text articles were then screened independently by two raters. Articles were included if studies: (a) were conducted in LMIC; (b) included samples of autistic children (age < 10); (c) evaluated psycho-social interventions delivered by non-specialists; (d) reported child outcomes; and (e) were peer-reviewed full-texts in English. Two established frameworks – @Practicewise and NDBI-Fi framework - were then used to ascertain the commonly delivered components of these interventions.

Results

Two studies met the inclusion criteria. Both studies evaluated parent-mediated interventions delivered by non-specialists in South Asia. Through the two frameworks, we identified elements and techniques that had been delivered successfully by non-specialists.

Conclusion

There is evidence from two acceptability and feasibility trials that non-specialists can be trained to deliver some intervention elements and techniques within parent-mediated interventions, with good fidelity and acceptability and evidence of effectiveness. The review points up the lack of a widespread evidence base in this area and need for further research in low resourced settings, including well-powered trials and mechanistic analyses to identify active ingredients. A focus on the pre-requisites for non-specialist delivery is critical to reduce inequity and provide universal health coverage within resource-constrained health systems.
Identifying the Service Capability of Long-Term Care Facilities in China: An e-Delphi Study
Authors: Liu Wen , Hu Min , Chen Wen
Published: June 2022

Objective

This study develops a group of service capability indicators for long-term care facilities to assess their current conditions and makes it the first step toward the improvement of service capability in China.

Methods

We constructed an initial indicator framework based on the characteristics of long-term care services and a literature review. Potential indicators were collected, and a 2-round modified web-based Delphi process was conducted by a national multidisciplinary expert panel to construct a service capability evaluation index system. The accepted competencies of indicators were established with mean scores in all three scoring criteria (importance, feasibility, and sensitivity) ≥ 4.0, consensus rate reached 70.0%, and a coefficient of variation ≤ 0.25.

Results

A new indicator framework covering 2 dimensions of inputs and activities was developed in this study. The initial 35 indicators formed an indicator pool for the Delphi questionnaire. According to the final consensus of the expert panel, the Delphi consultation resulted in an index system comprised 31 tertiary indicators across six subdimensions (i) staffing; (ii) facilities and equipment; (iii) funding; (iv) medical inspection services; (v) health management services; (vi) institutional standard management.

Conclusion

This study developed a set of indicators suitable for the long-term care system in China and is expected to be applied to measure and improve the service capability of long-term care facilities. In addition, these indicators can be used for comparisons between different LTCFs and provide an evidence basis for the further development of capability assessment tools.
A Machine Learning Algorithm for Predicting the Risk of Developing to M1b Stage of Patients With Germ Cell Testicular Cancer
Authors: Ding Li , Wang Kun , Zhang Chi , Zhang Yang , Wang Kanlirong , Li Wang , Wang Junqi
Published: June 2022

Objective:

Distant metastasis other than non-regional lymph nodes and lung (i.e., M1b stage) significantly contributes to the poor survival prognosis of patients with germ cell testicular cancer (GCTC). The aim of this study was to develop a machine learning (ML) algorithm model to predict the risk of patients with GCTC developing the M1b stage, which can be used to assist in early intervention of patients.

Methods

The clinical and pathological data of patients with GCTC were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Combing the patient's characteristic variables, we applied six machine learning (ML) algorithms to develop the predictive models, including logistic regression(LR), eXtreme Gradient Boosting (XGBoost), light Gradient Boosting Machine (lightGBM), random forest (RF), multilayer perceptron (MLP), and k-nearest neighbor (kNN). Model performances were evaluated by 10-fold cross-receiver operating characteristic (ROC) curves, which calculated the area under the curve (AUC) of models for predictive accuracy. A total of 54 patients from our own center (October 2006 to June 2021) were collected as the external validation cohort.

Results

A total of 4,323 patients eligible for inclusion were screened for enrollment from the SEER database, of which 178 (4.12%) developing M1b stage. Multivariate logistic regression showed that lymph node dissection (LND), T stage, N stage, lung metastases, and distant lymph node metastases were the independent predictors of developing M1b stage risk. The models based on both the XGBoost and RF algorithms showed stable and efficient prediction performance in the training and external validation groups.

Conclusion

S-stage is not an independent factor for predicting the risk of developing the M1b stage of patients with GCTC. The ML models based on both XGBoost and RF algorithms have high predictive effectiveness and may be used to predict the risk of developing the M1b stage of patients with GCTC, which is of promising value in clinical decision-making. Models still need to be tested with a larger sample of real-world data.
An Antimicrobial Treatment Assessment of Serratia marcescens Bacteremia and Endocarditis
Authors: Slain Douglas , Howard Catessa , Cooper C. Garret
Published: June 2022

We assessed the treatment of Serratia marcescens bacteremia and endocarditis in one of the largest single center studies. We could not identify an advantage with any particular antibiotic treatment regimen in this study. Induction of AmpC or selection of ESBL organisms was not displayed by any of the organisms.
Embodied Virtual Patients as a Simulation-Based Framework for Training Clinician-Patient Communication Skills: An Overview of Their Use in Psychiatric and Geriatric Care
Authors: Chaby Laurence , Benamara Amine , Pino Maribel , Prigent Elise , Ravenet Brian , Martin Jean-Claude , Vanderstichel Hélène , Becerril-Ortega Raquel , Rigaud Anne-Sophie , Chetouani Mohamed
Published: June 2022

Clinician-patient communication is essential to successful care and treatment. However, health training programs do not provide sufficient clinical exposure to practice communication skills that are pivotal when interacting with patients exhibiting mental health or age-related disorders. Recently, virtual reality has been used to develop simulation and training tools, in particular through embodied virtual patients (VP) offering the opportunity to engage in face-to-face human-like interactions. In this article, we overview recent developments in the literature on the use of VP-simulation tools for training communicative skills in psychiatry and geriatrics, fields in which patients have challenging social communication difficulties. We begin by highlighting the importance of verbal and non-verbal communication, arguing that clinical interactions are an interpersonal process where the patient’s and the clinician’s behavior mutually shape each other and are central to the therapeutic alliance. We also highlight the different simulation tools available to train healthcare professionals to interact with patients. Then, after clarifying what communication with a VP is about, we propose an overview of the most significant VP applications to highlight: 1) in what context and for what purpose VP simulation tools are used in psychiatry (e.g. depression, suicide risk, PTSD) and geriatrics (e.g., care needs, dementia), 2) how VP are conceptualized, 3) how trainee behaviors are assessed. We complete this overview with the presentation ofVirtuAlz, our tool designed to train health care professionals in the social skills required to interact with patients with dementia. Finally, we propose recommendations, best practices and uses for the design, conduct and evaluation of VP training sessions.
Carbon, Nitrogen, Phosphorus, and Extracellular Soil Enzyme Responses to Different Land Use
Authors: Uwituze Yvonne , Nyiraneza Judith , Fraser Tandra D. , Dessureaut-Rompré Jacynthe , Ziadi Noura , Lafond Jean
Published: June 2022

Extracellular soil enzymes play a key role in soil organic matter decomposition and nutrient cycling. However, it is not fully understood how these enzymes respond to different land use. Long-term research studies were used to evaluate how diversified management practices affect extracellular enzymes driving C cycling [phenol oxidases (PO), peroxidases (PP), α-glucosidase (AG), β-glucosidase (BG), cellobiohydrolase (CB), β-1,-4-Nacetylglucosaminidase (NAG)], N cycling [leucine aminopeptidase (LAP)], and P cycling [phosphomonoesterase (PME)]. The soil pH, contents of total organic C, total N, mehlich-3 P, soil respiration and soil nitrogen supply capacity were also measured. Different land use included tillage frequency, tillage regimes, mineral N fertilization, crop rotations and liquid dairy manure. Compared to medium or high tillage frequency, low tillage frequency increased total organic C and total N and soil respiration as well as NAG and PME activities, whereas it decreased soil nitrogen supply, mehlich-3 P, and soil pH, as well as PO, PP, AG, BG, CB, and LAP activities. Non till was associated with lower PP and PO activities than moldboard plow. Nitrogen fertilization decreased soil pH and PO activity but increased PME activity. Barley (Hordeum vulgare) in rotation with forage increased total organic C, total N, soil nitrogen supply and soil respiration by 31, 21, 44, and 33%, respectively, in comparison with barley in monoculture. The application of liquid dairy manure increased soil pH, total N and soil nitrogen supply and soil enzyme activities (AG, BG, NAG) in comparison to the mineral N fertilizer. When principal component analysis was performed, soil pH, PO, PP, CB, LAP, and PME were grouped in the first component, which explained the highest variance. This is the core group controlling the C, N, and P cycling. The activities of C, N, and P acquiring enzymes, soil nitrogen supply and soil respiration were related to changes in soil total C and N, and extractable P contents across a broad range of management practices. Increased PO and PP activities reflect total C decline.
Hip Abductor Muscle Fatigue Induces Different Strategies During Disrupted Postural Control
Authors: Dury Jeanne , Ravier Gilles , Michel Fabrice
Published: June 2022

Background

Ankle sprain is one of the most common injuries in sport, and hip abductor muscle weakness has recently been reported as a predisposing factor. Currently, the influence of hip abductor muscle fatigue on ankle joint control has not been elucidated during an ankle disturbed balance exercise. This study aimed to determine the influence of hip abductor muscle fatigue on ankle joint control during a disturbed balance task, and to consider inter-individual variability in the kinematic and neuromuscular reorganizations implemented.

Methods

Twenty-six healthy subjects (13 males; 13 females) performed a unipedal postural balance task with eyes closed before and after a fatiguing exercise (up to a 50% decrease in strength) of the hip abductor muscles. Subjects completed balance task while equipped with an ankle destabilization device that allows inversion/eversion movements. Electromyographic (EMG) activity of the gastrocnemius lateralis (GastL), peroneus longus (PL) and brevis, tibialis anterior, and gluteus medius were recorded during task. Kinematics (e.g., frontal foot angulation) of the ankle complex were determined using inertial measurement units.

Results

In the overall group, no significant time, sex or interaction effect was observed for kinematic and EMG variables. However, when considering individual responses to hip fatigue, 14 subjects decreased the standard deviation of frontal angulation (−30%) suggesting enhancement of ankle joint control, while 12 subjects increased it (+46%). Normalized EMG for PL and GastL muscles changed with fatigue for both these groups. However, variations were significantly different between groups (p = 0.027 for PL and p = 0.006 for GastL). Indeed, the contribution of ankle muscles increased for the enhanced-stability group while no change for the impaired-stability group.

Conclusion

These results highlight that subject adopt different neuromuscular and kinematic ankle strategies to control ankle destabilization in response to hip abductor muscle fatigue. Frontal foot angulation variability seemed to be a valuable marker to detect the type of strategy employed. The strategy adopted by the impaired-stability group might have important implications when analyzing risk factors for ankle sprains. Further studies should consider individual responses to fatigue, to understand which factor could predispose athletes to use of one or other strategy.
Low Level of Dietary Organic Trace Minerals Improved Egg Quality and Modulated the Status of Eggshell Gland and Intestinal Microflora of Laying Hens During the Late Production Stage
Authors: Dong Yuanyang , Zhang Keke , Han Miaomiao , Miao Zhiqiang , Liu Ci , Li Jianhui
Published: June 2022

This study aimed to investigate the effects of dietary organic trace minerals on egg quality and intestinal microflora of laying hens during the late production stage. In total, 1,080 Jinghong-1 laying hens aged 57 weeks were randomly assigned to five treatment groups: CON, basal diet containing about 6, 29, 49, and 308 mg·kg−1 of Cu, Mn, Zn, and Fe; IT100, basal diet supplemented with 10, 80, 80, and 60 mg·kg−1 of Cu, Mn, Zn, and Fe (each as inorganic sulfates), respectively; OT20, basal diet supplemented with 2, 16, 16, and 12 mg·kg−1 of Cu, Mn, Zn, and Fe (each as organic trace minerals chelated with lysine and methionine in the ratio of 2:1 amino acid: organic trace minerals), respectively; OT30, basal diet supplemented with 3, 24, 24, and 18 mg·kg−1 of organic Cu, Mn, Zn, and Fe, respectively; and OT50, basal diet supplemented with 5, 40, 40, and 30 mg·kg−1 of organic Cu, Mn, Zn, and Fe, respectively. Overall, OT20, OT30, and OT50 had equal or higher potential to promote Cu, Mn, Zn, and Fe deposition in egg yolks compared with IT100. In addition, OT50 enhanced the eggshell breaking strength and the antioxidant status of the eggshell gland. Cecal microbiota, including Barnesiellaceae and Clostridia, were significantly decreased in IT100- and OT50-treated hens compared with the CON group. Clostridia UCG-014 was negatively correlated with eggshell weight and OCX-32. In conclusion, reduced supplementation of organic trace minerals can improve the eggshell quality and trace mineral deposition, possibly by modulating genes involved in the eggshell formation in the eggshell gland and by controling of the potentially harmful bacteria Barnesiellaceae and Clostridiales in the cecum. Inorganic trace minerals may be effectively replaced by low level of complex organic trace minerals in laying hens during the late production stage.
When Civil Servants Go Frontstage—The Mediatization of the Role of the Civil Servant during the COVID-19 Crisis
Authors: Poulsen Birgitte
Published: June 2022

Mediatization scholars have shown how institutions adapt to the penetrating role of the media. This article investigates the mediatization of the civil servant role when moving from their well-known backstage role to a frontstage role. The COVID-19 pandemic is seen as an extreme case, where some civil servants were entitled key, frontstage roles in the handling of the pandemic, compared to their normal backstage role. Thus, the pandemic has created an opportunity to study the frontstage role of civil servants as a form of mediatization. Theoretically, the study provides a conceptual framework for analyzing the mediatized role of the civil servant by linking theories on mediatization and public administration with Goffman’s role theory. Empirically, the article provides an example of a hyper-mediatized civil servant during the extreme case of the COVID-19 pandemic in Denmark. The article explores how media logic entangles with the logic of bureaucracy, creating a new role for part of the civil service, resulting in governance dilemmas. The article thus contributes to the mushrooming literature on the mediatization of central government, showing the implications of a mediatized role of the civil servant, such as competition with the minister, increased vulnerability for the civil service, and blurred boundaries between administration/expertise on the one hand and politics on the other.
Development and Numerical Simulation of a Precision Strip-Hole Layered Fertilization Subsoiler While Sowing Maize
Authors: Wang Weiwei , Song Jiale , Zhou Guoan , Quan Longzhe , Zhang Chunling , Chen Liqing
Published: June 2022

The traditional fertilizer application methods have serious problems of environmental pollution and soil degradation due to low utilization rates in the Huang–Huai–Hai Plain of China. In this study, the conservation tillage strip-hole layered fertilization method was proposed and a precision strip-hole layered fertilizer subsoiler was designed. To meet the requirements for deep tillage strip-hole layered fertilizer application, theoretical analysis and parameter calculations were first carried out on the fertilizer application type hole wheel, and then the main factors affecting the fertilizer application effect of a strip-hole layered fertilizer shovel were analyzed. The effect of forwarding speed, angle of fertilizer tube installation (AFT) and angle of unloading fertilizer (AUF) on the middle and lower layers of the fertilizer distribution length (FDT) and fertilization amount deviation stability coefficient (FADSC) was studied using the discrete element method (DEM). The three-factor three-level full-factors test design method was adopted. Simulation results showed that the FDT and the FADSC increased as the forward speed increased; the FDT decreased as the AFT and the AUF increased; an increased FADSC was observed at a middle angle of the AFT and the AUF. The minimum FADSC was obtained for a combination of parameters with a forward speed of 2 km/h, the AFT of 35° and the AUF of 60°, corresponding to the FADSC of 2.49% in the middle layer and 2.93% in the lower layer while satisfying the FDT condition. The results of the field trials showed that the FADSC was 11.36% and 12.42%, respectively, an increase of 8.87% and 9.49%, respectively, compared to the simulation results, validating the simulation model. The new way of fertilizer application methods and a theoretical basis were provided for the design of hole application machinery.
Environmental LCA of Precision Agriculture for Stone Fruit Production
Authors: Núñez-Cárdenas Pablo , Diezma Belén , San Miguel Guillermo , Valero Constantino , Correa Eva C.
Published: June 2022

Precision agriculture is a concept that encompasses various technologies aimed at optimizing the management of agricultural activities. The main aim of this investigation is to evaluate the environmental and economic performance of precision agriculture practices on the production of a stone fruit crop (nectarine) using a life cycle approach and to consider a cradle-to-farm gate scope. The results have been compared against the traditional uniform application (UA). The analysis considers five impact categories, including climate change, photochemical ozone formation, acidification, eutrophication, and water use. The foreground inventory data was provided by a local producer in Southern Spain, and the background information was sourced from commercial Life Cycle Inventory (LCI) databases. The results show that the manufacturing of crop inputs (mainly fertilizers, but also crop management inputs) is responsible for most of the damage generated in all the impact categories, except for water use. The reduced input requirements associated with the application of VA techniques resulted in significantly lower economic costs and environmental savings throughout the life cycle of the production system, which ranged on average between 12–26%.
Camera Trapping Reveals Spatiotemporal Partitioning Patterns and Conservation Implications for Two Sympatric Pheasant Species in the Qilian Mountains, Northwestern China
Authors: Zhang Dexi , An Bei , Chen Liuyang , Sun Zhangyun , Mao Ruirui , Zhao Changming , Zhang Lixun
Published: June 2022

Studying the spatio-temporal niche partitioning among closely related sympatric species is essential for understanding their stable coexistence in animal communities. However, consideration of niche partitioning across multiple ecological dimensions is still poor for many sympatric pheasant species. Here, we studied temporal activity patterns and spatial distributions of the Blue Eared Pheasant (EP, Crossoptilon auritum) and Blood Pheasant (BP, Ithaginis cruentus) in the Qilian Mountains National Nature Reserve (QMNNR), Northwestern China, using 137 camera traps from August 2017 to August 2020. Kernel density estimation was applied to analyze diel activity patterns, and the Maxent model was applied to evaluate their suitable distributions and underlying habitat preferences. Eight Galliformes species were captured in 678 detection records with 485 records of EP and 106 records of BP over a total of 39,206 camera days. Their monthly activity frequencies demonstrate temporal partitioning but their diel activity patterns do not. Furthermore, 90.78% of BP distribution (2867.99 km2) overlaps with the distribution of EP (4355.86 km2) in the QMNNR. However, BP manifests a high dependence on forest habitats and shows larger Normalized Difference Vegetation Index (NDVI) values, while EP showed obvious avoidance of forest with NDVI greater than 0.75. Hence, differentiation in monthly activity patterns and partitioning in habitat preference might facilitate their coexistence in spatiotemporal dimensions. Conservation actions should give priority to highly overlapping areas in the center and east of the QMNNR and should strengthen forest landscape connectivity, as they provide irreplaceable habitats for these threatened and endemic Galliformes.
Efficacy of Lidocaine Topical Solution in Reducing Discomfort Reaction of Horses to Intramuscular Vaccination
Authors: Torcivia Catherine , McDonnell Sue
Published: June 2022

Vaccinations via intramuscular injection are a key component of preventative health care in horses. Development of problematic behavioral aversion to injections is quite common. Our clinical impression has been that topical anesthetic applied to injection sites can reduce the behavioral reaction; however, this has not been critically tested. To blindly evaluate efficacy, either 5% or 10% topical lidocaine solution or 0% control was applied to injection sites for 78 ponies two minutes before intramuscular vaccination. Mean reaction scores on a scale of 0–3 were 0.84 (se 0.18) for 5% lidocaine solution, 0.62 (se 0.14) for 10% lidocaine solution, compared to 1.30 (se 0.19) for 0% control solution. Reaction scores for both the 5% and 10% lidocaine were significantly lower than for the control group. Additionally, the proportion of subjects with a reaction greater than a slight flinch was 2 of 25 for the 5% lidocaine, 5 of 26 for the 10% lidocaine and 15 of 27 for the 0% lidocaine control. For both the 5% and 10% lidocaine groups, the proportion differed significantly from the control. The difference between the 5% and 10% lidocaine groups was not statistically significant. These findings confirm our clinical impression that application of topical anesthetic just two minutes in advance of intramuscular injection can effectively reduce the behavior reaction of horses.
Temporal and Spatial Activity Patterns of Sympatric Wild Ungulates in Qinling Mountains, China
Authors: Li Jia , Xue Yadong , Liao Mingfu , Dong Wei , Wu Bo , Li Diqiang
Published: June 2022

Dramatic increases in populations of wild ungulates have brought a new ecological issue in the Qinling mountains. Information on species’ niche differentiation will contribute to a greater understanding of the mechanisms of coexistence, so as to ultimately benefit the conservation and management of ecological communities. In this study, camera trapping was used to investigate spatial and temporal activity patterns of sympatric wild ungulates in the Qinling Mountains of China, where top predators were virtually absent. We obtained 15,584 independent detections of seven wild ungulate species during 93,606 camera-trap days from April 2014 to October 2017. Results showed that (i) the capture rate differed significantly across species, with the capture rate of reeve muntjac being significantly higher than that of other species; (ii) the wild boar had a higher occupancy rates (ψ = 0.888) than other six ungulates, and distance to settlements had a negative relationship with wild boar (β = −0.24 ± 0.17); (iii) the forest musk deer and mainland serow had low spatial overlaps with other five wild ungulates, while spatial overlap indices of any two given pairs of wild ungulates were relatively high; (iv) all wild ungulates species (expect wild boar) were mainly active during crepuscular and diurnal periods, and showed bimodal activity peaks at around 05:00–07:00 and 17:00–19:00; and finally, (v) all wild ungulates showed moderate to high temporal overlaps. The results provided detailed information of the spatial and temporal ecology of wild ungulate communities in forest ecosystems of China, which also would be a guide to establish conservation priorities as well as efficient management programs.
Yucca schidigera Improves Performance and Lowers Oocyst Counts in Eimeria Challenged Broilers
Authors: Kozłowski Krzysztof , Vervenne-Zetteler Peggy , Konieczka Paweł , Szymański Łukasz , van Vilsteren Anouk
Published: June 2022

Coccidiosis is one of the main challenges for the worldwide poultry industry, and several anticoccidial treatments have been used to fight these protozoa. Resistance of Eimeria parasites against anticoccidials—and the public opinion about these treatments—demands for alternatives. In this trial, we tested Yucca schidigera (500 g/T) as a natural alternative in broilers challenged with Eimeria. This treatment was compared to three other treatments: An unchallenged control, a challenged control, and a challenged anticoccidial (625 g/T) treatment with focus on performance, oocyst per gram counts (OPG), and lesion scores. Both the anticoccidial and the Yucca schidigera group showed significant improvement in body weight (2.150 and 2.058 vs. 1.998 and 1.971 kg). growth (60.2 and 57.6 vs. 55.8 and 55.1 g/d). and feed-conversion ratio (1.456 and 1.510 vs. 1.527 and 1.575), compared to both control groups. No significant differences were found between the treatments on OPG collection days 18 and 25. On day 35, lowest OPG counts were found in the unchallenged group (93), followed by the Yucca schidigera group (114), the anticoccidial group (243), and the challenged group (650). Adding Yucca schidigera abolished the effect of the challenge resulting in comparable (FCR) or better (ADG) performance results compared to the unchallenged birds. Yucca schidigera consistently showed lower numbers for OPG counts compared to the anticoccidial and challenged group. Therefore, Yucca schidigera can be considered as an effective alternative for anticoccidial treatment in broilers.
Occurrence of Serratia marcescens Carrying blaIMP-26 and mcr-9 in Southern China: New Insights in the Evolution of Megaplasmid IMP-26
Authors: Zhong Yuxia , Liu Wanting , Yuan Peibo , Yang Ling , Xu Zhenbo , Chen Dingqiang
Published: June 2022

The spread of multidrug-resistant enterobacteria strains has posed a significant concern in public health, especially when the strain harbors metallo-beta-lactamase (MBL)-encoding and mobilized colistin resistance (mcr) genes as such genetic components potentially mediate multidrug resistance. Here we report an IncHI2/2A plasmid carrying blaIMP-26 and mcr-9 in multidrug-resistant Serratia marcescens human isolates YL4. Antimicrobial susceptibility testing was performed by the broth microdilution method. According to the results, S. marcescens YL4 was resistant to several antimicrobials, including β-lactams, fluorquinolones, sulfanilamide, glycylcycline, and aminoglycosides, except for amikacin. To investigate the plasmid further, we conducted whole-genome sequencing and sequence analysis. As shown, S. marcescens YL4 possessed a circular chromosome with 5,171,477 bp length and two plasmids, pYL4.1 (321,744 bp) and pYL4.2 (46,771 bp). Importantly, sharing high similarity with plasmids pZHZJ1 and pIMP-26, pYL4.1 has an IncHI2/2A backbone holding a variable region containing blaIMP-26, mcr-9, and two copies of blaTEM-1B. After comprehensively comparing relevant plasmids, we proposed an evolutionary pathway originating from ancestor pZHZJ1. Then, via an acquisition of the mcr-9 element and a few recombination events, this plasmid eventually evolved into pYL4.1 and pIMP-26 through two different pathways. In addition, the phage-like plasmid pYL4.2 also carried a blaTEM-1B gene. Remarkably, this study first identified a multidrug-resistant S. marcescens strain co-harboring blaIMP-26 and mcr-9 on a megaplasmid pYL4.1 and also included a proposed evolutionary pathway of epidemic megaplasmids carrying blaIMP-26.
Nutraceuticals: Focus on Anti-Inflammatory, Anti-Cancer, Antioxidant Properties in Gastrointestinal Tract
Authors: Caponio Giusy , Lippolis Tamara , Tutino Valeria , Gigante Isabella , De Nunzio Valentina , Milella Rosa , Gasparro Marica , Notarnicola Maria
Published: June 2022

In recent years, nutraceuticals have gained great popularity, owing to their physiological and potential health effects, such as anti-inflammatory, anti-cancer, antioxidant, and prebiotic effects, and their regulation of lipid metabolism. Since the Mediterranean diet is a nutritionally recommended dietary pattern including high-level consumption of nutraceuticals, this review aimed to summarize the main results obtained by our in vitro and in vivo studies on the effects of the major constituents of the Mediterranean diet (i.e., extra virgin olive oil compounds, polyunsaturated fatty acids, and fruit components). Based on experimental studies, the therapeutic purpose of nutraceuticals depends on their bioavailability, solubility, toxicity, and delivery system. This review provides more in-depth knowledge on the effects linked to nutraceuticals administration on human health, focusing the gastrointestinal tract and suggesting specific dietary components for personalized adjuvant therapies.
Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells
Authors: Sridevi Gurubaran Iswariyaraja , Hytti Maria , Kaarniranta Kai , Kauppinen Anu
Published: June 2022

Emerging evidence suggests that the intracellular clearance system plays a vital role in maintaining homeostasis and in regulating oxidative stress and inflammation in retinal pigment epithelium (RPE) cells. Dysfunctional proteasomes and autophagy in RPE cells have been associated with the pathogenesis of age-related macular degeneration. We have previously shown that the inhibition of proteasomes using MG-132 activates the NLR family pyrin domain containing 3 (NLRP3) inflammasome in human RPE cells. However, MG-132 is a non-selective proteasome inhibitor. In this study, we used the selective proteasome inhibitor epoxomicin to study the effect of non-functional intracellular clearance systems on inflammasome activation. Our data show that epoxomicin-induced proteasome inhibition promoted both nicotinamide adenine dinucleotide phosphate oxidase and mitochondria-mediated oxidative stress and release of mitochondrial DNA to the cytosol, which resulted in potassium efflux-dependent absence in melanoma 2 (AIM2) inflammasome activation and subsequent interleukin-1β secretion in ARPE-19 cells. The non-specific proteasome inhibitor MG-132 activated both NLRP3 and AIM2 inflammasomes and oxidative stress predominated as the activation mechanism, but modest potassium efflux was also detected. Collectively, our data suggest that a selective proteasome inhibitor is a potent inflammasome activator in human RPE cells and emphasize the role of the AIM2 inflammasome in addition to the more commonly known NLRP3 inflammasome.
A Census of Human Methionine-Rich Prion-like Domain-Containing Proteins
Authors: Aledo Juan Carlos
Published: June 2022

Methionine-rich prion-like proteins can regulate liquid–liquid phase separation processes in response to stresses. To date, however, very few proteins have been identified as methionine-rich prion-like. Herein, we have performed a computational survey of the human proteome to search for methionine-rich prion-like domains. We present a census of 51 manually curated methionine-rich prion-like proteins. Our results show that these proteins tend to be modular in nature, with molecular sizes significantly greater than those we would expect due to random sampling effects. These proteins also exhibit a remarkably high degree of spatial compaction when compared to average human proteins, even when protein size is accounted for. Computational evidence suggests that such a high degree of compactness might be due to the aggregation of methionine residues, pointing to a potential redox regulation of compactness. Gene ontology and network analyses, performed to shed light on the biological processes in which these proteins might participate, indicate that methionine-rich and non-methionine-rich prion-like proteins share gene ontology terms related to the regulation of transcription and translation but, more interestingly, these analyses also reveal that proteins from the methionine-rich group tend to share more gene ontology terms among them than they do with their non-methionine-rich prion-like counterparts.