bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Images in Constructing Public Opinion About Environmental Matters in Malaysia
Authors: Mohamad Saleh Mohamad Saifudin , Heinrichs Harald , Nik Hasan Nik Norma
Published: November 2020

This paper provides a discussion on the perception of Malaysian media and environmental non-governmental organisations (ENGOs) on the role of images in shaping the public's mind about environmental matters. Two methods were employed for this study. First, a total of 24 participants from the Malaysian media and ENGOs were interviewed. Second, a total of 2,050 environmental articles on media newspapers and ENGOs newsletters from the period of 2012 to 2014 were collected for the quantitative content analysis. The findings from interview confirmed that pictures were labelled by journalists and ENGOs staff as the most important tool in presenting the reality of the environmental problems to the public. This is because, upon seeing the pictures accompanying environmental articles, readers will gain more trust of the environmental information. This was in harmony with the results of the quantitative content analysis, where more than 60% of pictures were found on environmental articles.
A Framework for Homogeneous Cross-Project Defect Prediction
Authors: Goel Lipika , Sharma Mayank , Khatri Sunil Kumar , Damodaran D.
Published: November 2020

Often, the prior defect data of the same project is unavailable; researchers thought whether the defect data of the other projects can be used for prediction. This made cross project defect prediction an open research issue. In this approach, the training data often suffers from class imbalance problem. Here, the work is directed on homogeneous cross-project defect prediction. A novel ensemble model that will perform in dual fold is proposed. Firstly, it will handle the class imbalance problem of the dataset. Secondly, it will perform the prediction of the target class. For handling the imbalance problem, the training dataset is divided into data frames. Each data frame will be balanced. An ensemble model using the maximum voting of all random forest classifiers is implemented. The proposed model shows better performance in comparison to the other baseline models. Wilcoxon signed rank test is performed for validation of the proposed model.
A Survey and Taxonomy of Intent-Based Code Search
Authors: Shivakumar Shailesh Kumar
Published: November 2020

In this paper, the authors introduce the novel concept of intent-based code search that categorizes code search goals into a hierarchy. They will explore state-of-the-art techniques in source code search covering various tools, techniques, and algorithms related to source code search. They will survey the code search field through the core use cases of code search such as code reusability, code understanding, and code repair. They propose a user intent-based taxonomy based on the code search goals. The code search goal taxonomy is derived based on deep analysis of literature survey of code search, and the taxonomy is validated based on their exclusive developer survey conducted as part of this paper. The code search goal taxonomy is based on logical categorization of code search goals and shared characteristics (query type, expected response, and such) for each of the categories in the taxonomy. The paper also details the latest trends and surveys the code search tools and the implications on tool design.
An Empirical Study on Initializing Centroid in K-Means Clustering for Feature Selection
Authors: Saxena Amit , Wang John , Sintunavarat Wutiphol
Published: November 2020

One of the main problems in K-means clustering is setting of initial centroids which can cause misclustering of patterns which affects clustering accuracy. Recently, a density and distance-based technique for determining initial centroids has claimed a faster convergence of clusters. Motivated from this key idea, the authors study the impact of initial centroids on clustering accuracy for unsupervised feature selection. Three metrics are used to rank the features of a data set. The centroids of the clusters in the data sets, to be applied in K-means clustering, are initialized randomly as well as by density and distance-based approaches. Extensive experiments are performed on 15 datasets. The main significance of the paper is that the K-means clustering yields higher accuracies in majority of these datasets using proposed density and distance-based approach. As an impact of the paper, with fewer features, a good clustering accuracy can be achieved which can be useful in data mining of data sets with thousands of features.
Defending Deep Learning Models Against Adversarial Attacks
Authors: Mani Nag , Moh Melody , Moh Teng-Sheng
Published: November 2020

Deep learning (DL) has been used globally in almost every sector of technology and society. Despite its huge success, DL models and applications have been susceptible to adversarial attacks, impacting the accuracy and integrity of these models. Many state-of-the-art models are vulnerable to attacks by well-crafted adversarial examples, which are perturbed versions of clean data with a small amount of noise added, imperceptible to the human eyes, and can quite easily fool the targeted model. This paper introduces six most effective gradient-based adversarial attacks on the ResNet image recognition model, and demonstrates the limitations of traditional adversarial retraining technique. The authors then present a novel ensemble defense strategy based on adversarial retraining technique. The proposed method is capable of withstanding the six adversarial attacks on cifar10 dataset with accuracy greater than 89.31% and as high as 96.24%. The authors believe the design methodologies and experiments demonstrated are widely applicable to other domains of machine learning, DL, and computation intelligence securities.
Methods of Information Processing of Relative Motion in the Flying Groups of UAV
Authors: Galiautdinov Rinat
Published: November 2020

In this article, the author investigates information processing algorithms in order to determine the relative UAV motion parameters in a group flight and proposes an algorithm for estimating the leading UAV motion parameters from the results of relative motion measurements. Such researches are especially important nowadays in all the spheres where the drones are used and/or will be used. The author considers the problems of management of the UAV in the group flight, formulation of the problem for processing of the information in such the conditions. The article considers relative motion equation and the synthesis of information processing algorithms in the master-slave model of the flying group of UAV.
A Sound Framework for ICT Integration in Indian Teacher Education
Authors: Kundu Arnab
Published: November 2020

This conceptual analysis aimed at preparing a sound framework for healthy integration of information and communication technologies (ICTs) in Indian teacher education practices. An extensive and integrative literature review was made following the inclusion-exclusion criteria. The models proposed in several previous studies were also gone through and adequately contextualised with the needs and ethos of Indian teacher education programs to build an innovative framework leveraging the optimum potentials of ICTs in educational set up. The findings of the study synthesized with a proposal to build a sound framework for an ideal ICTs integration in Indian teacher education scenario based on seven cardinal principles of good practices with a major shift in emphasis from ‘education for ICT' to ‘ICT for education', effective to accost the educational transformations for 21st century India. The implication was that by adopting such a sound framework the teacher education in the country could exploit the genuine benefits of ICTs thereby augmenting its educational outputs to the fullest.
First-Year Teachers' Preparedness in Using Student Assessment Data
Authors: Garry Vanessa , Boyer Patricia G.
Published: November 2020

In an attempt to better understand if teachers are trained and prepared to use student assessment data, this study used a nationally representative data set. The public data source for this exploratory study was gathered from Schools and Staff Survey (SASS), specifically, the Public Teachers: 2011–12 database. The multiple linear regression findings revealed that teachers feel they influence the content of in-service professional development programs at their school. Also, school leaders should consider gender and race when creating training because results show that professional development experiences of gender and race/ethnicity are different. The article presents several recommendations for school leaders in public institutions.
The Impact of Nanomaterials on Fabrication Silicon Solar Cells by Pulsed Laser Deposition
Authors: Farman Shelan A. , Ibrahim Muayed K. , Aadim Kadhim Abdulwahid
Published: November 2020

Nanocarbon structures such as graphene (GR), single-walled carbon nanotubes (SWCNTs) as well as the multi-walled carbon nanotubes (MWCNTs) were deposited on crystalline n-type silicon wafers to fabricate nanoCarbon-Si solar cells. Nanocarbon films deposited on glass and porous silicon (PS) via pulse laser deposition (PLD) with the use of Q-Switching Nd: YAG laser with λ=1064 (nm), Energy (E)=700 (mJ), Repetition rate (f)=6 (HZ) under vacuum condition with 2.5×10-2 (mbar). The surface morphology, structure, and optical Nanocarbon thin films have been examined with the use of X-ray Diffraction (XRD), Atomic force microscope (AFM), FTIR spectrophotometer and UV-visible. In addition, the power conversion efficiency that is related to the prepared solar cells is estimated through J-V characterization. The PCE of all Nanocarbon/PS follows the orders; SWCNTs/PS < MWCNTs/PS< GR/PS.
Fabrication and Characterization Biomimetic Micro Actuators Using Ferrofluid-Silicone Composite Cantilevers
Authors: Deshmukh Shridhar Sampatrao , Pillai Priam V.
Published: November 2020

In this paper we have developed a simple and inexpensive method to fabricate cilia-like silicone rubber-ferrofluid composite cantilever beams. The technique described can generate highly reproducible arrays of these microcantilevers ranging from 1 mm to 0.4 mm in diameter. We use a laser cutter to create moulds for the cantilevers making it a low cost and reliable process. The iron particles from the ferrofluid can uniformly dispersed, randomly arranged or isolated on the tip of the cantilever. Cantilevers with 400 μm diameter and up to 10 mm length are tested with low magnetic field of 15mT. We obtained maximum deflection of 82.5o at 44 mT magnetic field.
Effect of Sisal Fiber-Snail Shell Hybrid Reinforcement on some Mechanical Properties and Moisture Uptake of Unsaturated Polyester Resin Based Composites
Authors: Oladele Isiaka Oluwole , Betiku Olakunle Timothy , Akinseye Joseph Gbenga , Makinde-Isola Baraka Abiodun
Published: November 2020

This study investigates the hybrid effect of chemically modified sisal fiber and snail shell particles on the performance of polyester composites. The sisal fiber used was extracted by soil retting method and some portions were treated with potassium hydroxide (KOH) and sodium hydroxide (NaOH) solutions, respectively. The snail shell was calcined before grinding and sieving into particle size of ˂75 μm. The composites were developed using randomly dispersed open mould technique by varying the reinforcements between 2-10 wt. %. The particulate snail shell was analyzed with XRF where it was discovered that Mn and Ni were the major constituents while the developed composites were also subjected to different tests in accordance with the existing ASTM standards. The results revealed that the incorporation of sisal fiber and snail shell particles in the polyester matrix resulted in better tensile and flexural properties. The performance of the materials in moisture environment showed that chemically modified sisal fiber samples reduce the tendency for moisture absorption. The influence of the modification was best for samples from KOH treated fiber compared to NaOH treated fiber. Hence, it was discovered that snail shell/modified sisal fiber aid the enhancement of the performance of the developed composites.
Physico-Chemical Properties of Nano ZrO2-Pillared Bentonite with Nickel as Supporting Metal
Authors: Mirzan Mohamad , Syoufian Akhmad , Wijaya Karna
Published: November 2020

Bentonite was modified through intercalation and calcination using a ZrOCl2 pillaring solution. To create nano Ni/ZrO2-bentonite catalyst, ZrO2 pillared bentonite was impregnated using Ni(NO3)2•6H2O precursor first, then followed by calcination and reduction. The physical-chemical properties of the catalyst was characterized by XRD (X-ray Diffractometer), FT-IR (Fourier Transform Infrared), surface acidity with NH3 vapor adsorption method, SAA (Surface Area Analyzer) and TEM (Transmission Electron Microscope). The results of characterization with XRD showed specific peaks for montmorillonite minerals with a monoclinic crystalline type and its chemical composition (Ca)(Al,Mg)6(Si4O10)3(OH)6.nH2O and after pillarization showed a shift in basal spacing d001 to the left (angle 2θ <5°). The typical peak indicating basal spacing d001 shift towards a smaller angle of 2θ was not very apparent after impregnation with nickel metal. Qualitative determination of acidity after adsorption of ammonia showed characteristics at 1404-1635 cm-1 wavenumbers with increasingly sharp spectra indicating increased acidity of the catalyst (Brǿnsted and Lewis acids). Surface area showed a significant increase from 27.385 m2/g to 174.208 m2/g after pillarization and impregnation of nickel metal.
RU486: è solo una questione medico-farmacologica?
Authors: Spagnolo Antonio G.
Published: November 2020

Non disponibile.
Il passato dell’idea di progresso ed il futuro della bioetica
Authors: Sartea Claudio
Published: November 2020

L’articolo prende le mosse dal cinquantesimo anniversario del neologismo “bioetica” per rievocare la concezione genuina della bioetica nell’introduttore del termine, V.R. Potter, e recuperare la critica del progresso tecnoscientifico ben presente nei suoi scritti ed in quelli di pensatori e filosofi coevi. La conclusione, anche nello scenario conturbante della recente crisi pandemica, va sia nella direzione di un ridimensionamento del concetto di progresso in ambito medico, sia verso la proposta di un approfondimento della riflessione sugli scopi della ricerca e della terapia.
Who are the Assistant Cooks at the Community Child Centers in South Korea? Focus Group Interviews with Workfare Program Participants
Authors: Park Jiyoung , Park Chongwon , Kim Sanghee , Hoor Gill A. Ten , Hwang Gahui , Hwang Youn Sun
Published: November 2020

Purpose: Community child centers (CCCs) were introduced to provide after-school activities and care, including meal services to children from low-income families. The assistant cooks, who have the main responsibility for making and serving food at CCCs, are a major factor influencing the eating habits of children using CCCs. In this study, we tried to identify and understand who the assistant cooks are, what their job responsibilities are, and what they need in order to be able to provide children with healthy meals.Methods: Three focus group interviews were held with 17 workfare program participants who worked as assistant cooks at CCCs, and content analysis methods were applied using the NVivo 12 qualitative data analysis software.Results: The assistant cooks reflected on their perceptions of the children's health at the CCCs, their own cooking style, and their role at the CCCs. Additionally, barriers to the optimal provision of their services were pointed out, and improvements were suggested.Conclusion: The results of this study can be used as a fundamental resource for the development of tailored interventions that consider a child's unique environment to address health disparities, specifically with respect to childhood obesity.
Mastering your fellowship
Authors: Naidoo Mergan , Von Pressentin Klaus B. , Ross Andrew , Ras Tasleem
Published: November 2020

The series, ‘Mastering your Fellowship’, provides examples of the question format encountered in the written and clinical examinations, Part A of the Fellowship of the College of Family Physicians of South Africa (FCFP [SA]) examination. The series is aimed at helping family medicine registrars prepare for this examination. Model answers are available online.
Efficacy of vorinostat-sensitized intraperitoneal radioimmunotherapy with 64Cu-labeled cetuximab against peritoneal dissemination of gastric cancer in a mouse model
Authors: Tachibana Tomoko , Yoshii Yukie , Matsumoto Hiroki , Zhang Ming-Rong , Nagatsu Kotaro , Hihara Fukiko , Igarashi Chika , Sugyo Aya , Tsuji Atsushi B. , Higashi Tatsuya
Published: November 2020

Background:

Gastric cancer is a common cause of cancer-related death worldwide, and peritoneal dissemination is the most frequent metastatic pattern of gastric cancer. However, the treatment of this disease condition remains difficult. It has been demonstrated that intraperitoneal radioimmunotherapy (ipRIT) with 64Cu-labeled cetuximab (anti-epidermal growth factor receptor antibody; 64Cu-cetuximab) is a potential treatment for peritoneal dissemination of gastrointestinal cancer in vivo. Recent preclinical and clinical studies have also shown that a histone deacetylase inhibitor, vorinostat, effectively sensitized gastrointestinal cancer to external radiation.

Aim:

In the present study, we examined the efficacy of the combined use of vorinostat, as a radiosensitizer during ipRIT with 64Cu-cetuximab in a peritoneal dissemination mouse model with human gastric cancer NUGC4 cells stably expressing red fluorescent protein.

Methods:

The mouse model was treated by ipRIT with 64Cu-cetuximab plus vorinostat, each single treatment, or saline (control). Side effects, including hematological and biochemical parameters, were evaluated in similarly treated, tumor-free mice.

Results:

Coadministration of ipRIT with 64Cu-cetuximab + vorinostat significantly prolonged survival compared to control and each single treatment. No significant toxicity signals were observed in all treatment groups.

Conclusions:

Our data suggest that vorinostat is a potentially effective radiosensitizer for use during the treatment of peritoneal dissemination of gastric cancer by ipRIT with 64Cu-cetuximab.
Prognostic factors and clinical nomogram predicting survival in high-grade glioma
Authors: Tunthanathip Thara , Ratanalert Sanguansin , Sae-Heng Sakchai , Oearsakul Thakul , Sakarunchai Ittichai , Kaewborisutsakul Anukoon , Chotsampancharoen Thirachit , Intusoma Utcharee , Kitkhuandee Amnat , Vaniyapong Tanat
Published: November 2020

Background:

Genomic-based tools have been used to predict poor prognosis high-grade glioma (HGG). As genetic technologies are not generally available in countries with limited resources, clinical parameters may be still necessary to use in predicting the prognosis of the disease. This study aimed to identify prognostic factors associated with survival of patients with HGG. We also proposed a validated nomogram using clinical parameters to predict the survival of patients with HGG.

Methods:

A multicenter retrospective study was conducted in patients who were diagnosed with anaplastic astrocytoma (WHO III) or glioblastoma (WHO IV). Collected data included clinical characteristics, neuroimaging findings, treatment, and outcomes. Prognostic factor analysis was conducted using Cox proportional hazard regression analysis. Then, we used the significant prognostic factors to develop a nomogram. A split validation of nomogram was performed. Twenty percent of the dataset was used to test the performance of the developed nomogram.

Results:

Data from 171 patients with HGG were analyzed. Overall median survival was 12 months (interquartile range: 5). Significant independent predictors included frontal HGG (hazard ratio [HR]: 0.62; 95% confidence interval [CI]: 0.40–0.60), cerebellar HGG (HR: 4.67; 95% CI: 0.93–23.5), (HR: 1.55; 95% CI: 1.03–2.32; reference = total resection), and postoperative radiotherapy (HR: 0.18; 95% CI: 0.10–0.32). The proposed nomogram was validated using nomogram's predicted 1-year mortality rate. Sensitivity, specificity, positive predictive value, negative predictive value, accuracy, and area under the curve of our nomogram were 1.0, 0.50, 0.45, 1.0, 0.64, and 0.75, respectively.

Conclusion:

We developed a nomogram for individually predicting the prognosis of HGG. This nomogram had acceptable performances with high sensitivity for predicting 1-year mortality.
Merkel cell carcinoma in Turkey
Authors: Yildiz Fatih , Demirci Umut , Küçükarda Ahmet , Büyüksimsek Mahmut , Sakalar Teoman , Topcu Turkan Ozturk , Aslan Ferit , Tufan Gulnihal , Aydin Ovgu , Turna Hande , Babacan Nalan Akgul , Basoglu Tugba , Kurt Bediz , Yildiz Birol , Eren Tülay , Demiray Atike Gokcen , Gumusay Ozge , Arslan Cagatay , Özdemir Nuriye , Urun Yuksel , Baykara Meltem , Turan Nedim , Uysal Mukremin , Bilici Ahmet , Kavgaci Halil , Çiçin İrfan , Kilickap Saadettin , Paydas Semra
Published: November 2020

Background:

Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine carcinoma of the skin. In this study, we aimed to evaluate the clinicopathologic characteristics, treatment outcomes, and survival of MCC cases in Turkey.

Materials and Methods:

The patients diagnosed with MCC between 1999 and 2018 at twenty different centers in Turkey were included in the study. Patient and tumor characteristics and adjuvant and metastatis treatment outcomes were analyzed retrospectively.

Results:

The median age of totally 89 patients was 70 (26–93). The most common primary location was lower limbs (n = 29, 32.5%). Immunohistochemically, CK20 positivity was present in 59 patients (66.3%). Only two patients had secondary malignancy. The majority of the patients (n = 76, 85.4%) were diagnosed at the localized stage. Surgery was performed for all patients in the early stage, and adjuvant radiotherapy or/and chemotherapy was applied to 52.6% (n = 40) of nonmetastatic patients. The median follow-up was 29 months. Recurrence developed in 21 (27.6%) of the 76 patients who presented with local or regional disease. Two-year disease-free survival (DFS) was 68.1% and 5-year DFS was 62.0% for localized stage. The 5-year DFS was similar for patients receiving adjuvant treatment (chemotherapy, radiotherapy, or sequential chemoradiotherapy) and without adjuvant therapy (P > 0.05). Two-year overall survival in patients who presented with localized disease was 71.3% and 18.5% in metastatic patients (P < 0.001). In the metastatic stage, platinum/etoposide combination was the most preferred combination regimen. Median progression-free survival (PFS) in first-line chemotherapy was 7 months (95% confidence interval: 3.5–10.5 months; standart error: 1.78).

Conclusions:

Although MCC is rare in Turkey, the incidence is increasing. Gender, CK20 status, tumor size, lymph node involvement, and adjuvant treatment were not associated with recurrence.
Polymer coating in soybean seed treatment and their relation to leaching of chemicals
Authors: Ludwig Eduardo José , Nunes Ubirajara Russi , Prestes Osmar Damian , Fagundes Lovane Klein , Fernandes Tiéle Stuker , Saibt Nathália
Published: November 2020

This study evaluated the physiological quality and quantified the efficiency of polymer in reducing the loss of phytosanitary products by leaching from soybean seeds of different diameters and in different treatments. Two lots of seed and two types of treatments were tested: polymers associated with seed treatment, and polymer application in layers after the seed treatment. For that, the following treatments were analyzed: Control= no seed treatment; Treat+pol= seed treatment + polymers in the mix; Treat/pol= seed treatment + polymers applied in layers; Treat= seed treatment. To evaluate seed treatment retention by the polymers, extraction equipment was employed and leaching of the active ingredient thiamethoxam was quantified. Evaluation of physical quality was conducted with tests of germination rate, first count, emergence rate, accelerated aging, seedling length, seedling dry mass and moisture content. Polymer application associated with seed treatment was efficient in reducing losses by leaching, reducing product loss by 20%. No significant differences in retention and physiological quality were found when different methods for polymer application were compared. Bigger seeds presented greater vigor, but the germination rate was unaffected.
Monitoring of fluoride in the public water supply using electrometric or colorimetric analyses
Authors: Lins-Candeiro Caio Luiz , Dolenkei Karen Katlein , Paranhos Luiz Renato , Santos Douglas Queiroz , Cury Jaime Aparecido , Faquim Juliana Pereira da Silva
Published: November 2020

The surveillance of the concentration of fluoride in the public water supply aims to ensure the balance between the benefits (carie prevention) and risk (dental fluorosis) of water fluoridation programs. The aim of this study was to check the accuracy of two analytical methods for monitoring the concentration of fluoride in the public water supply of a Brazilian city. The STROBE checklist was used to aid the conduction of this study and report the results. It was an analytical, observational, and prospective study using the water supply of Uberlândia, MG, Brazil. We collected 126 water samples at 21 sites for six consecutive months and analyzed them using the fluoride ion selective electrode (F-ISE) method and colorimetry with SPADNS. The statistical analysis was performed descriptively and then the ANOVA and Student t-test for paired samples were applied. The results showed that the F-ISE method had a lower coefficient of variation (12.3%) than the SPADNS method (57.4%). There was no significant variation of the fluoride concentration in the water through the supply network evaluated either by F-ISE as SPADNS. We concluded that the electrometric method should be the first choice for use by laboratories that monitor fluoride concentration in the public supply water.
Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System in Children under the Age of 3 Years
Authors: Park Meerim , Han Jung Woo , Hahn Seung Min , Lee Jun Ah , Kim Joo-Young , Shin Sang Hoon , Kim Dong-Seok , Yoon Hong In , Hong Kyung Taek , Choi Jung Yoon , Kang Hyoung Jin , Shin Hee Young , Phi Ji Hoon , Kim Seung-Ki , Lee Ji Won , Yoo Keon Hee , Sung Ki Woong , Koo Hong Hoe , Lim Do Hoon , Shin Hyung Jin , Kim Hyery , Koh Kyung-Nam , Im Ho Joon , Ahn Seung Do , Ra Young-Shin , Baek Hee-Jo , Kook Hoon , Jung Tae-Young , Choi Hyoung Soo , Kim Chae-Yong , Park Hyeon Jin , Lyu Chuhl Joo
Published: November 2020

Purpose Atypical teratoid/rhabdoid tumor (ATRT) is a highly aggressive malignancy with peak incidence in children aged less than 3 years. Standard treatment for central nervous system ATRT in children under the age of 3 years have not been established yet. The objective of this study was to analyze characteristics and clinical outcomes of ATRT in children aged less than 3 years.Materials and Methods A search of medical records from seven centers was performed between January 2005 and December 2016.Results Forty-three patients were enrolled. With a median follow-up of 90 months, 27 patients (64.3%) showed at least one episode of disease progression (PD). The first date of PD was at 160 days after diagnosis. The 1- and 3-year progression-free survivals (PFS) were 51.2% and 28.5%, respectively. The 1- and 3-year overall survivals were 61.9% and 38.1%, respectively. The 3-year PFS was improved from 0% in pre-2011 to 47.4% in post-2011. Excluding one patient who did not receive any further therapy after surgery, 27 patients died due to PD (n=21), treatment-related toxicity (n=5), or unknown cause (n=1). In univariate analysis, factors associated with higher 3-year PFS were no metastases, diagnosis after 2011, early adjuvant radiotherapy, and high-dose chemotherapy (HDCT). In multivariate analysis, the use of HDCT and adjuvant radiotherapy remained significant prognostic factors for PFS (both p < 0.01).Conclusion Aggressive therapy including early adjuvant radiotherapy and HDCT could be considered to improve outcomes of ATRT in children under the age of 3 years.
О конечных группах
с формационно субнормальными нормализаторами силовских подгрупп
Authors: Vasil'ev Alexander Fedorovich , Vasilyeva Tatiana Ivanovna , Koranchuk A G
Published: November 2020

Пусть $\mathfrak{F}$ - формация. Изучены свойства
класса $\mathrm{w}^{*}\mathfrak{F}$ всех групп $G$, для которых
$\pi(G)\subseteq\pi(\mathfrak{F})$ и нормализаторы
всех силовских подгрупп $\mathfrak{F}$-субнормальны в $G$.
В частности, установлено, что такой класс является формацией,
замкнутой относительно взятия холловых подгрупп.
Найдены наследственные насыщенные формации $\mathfrak{F}$,
совпадающие с $\mathrm{w}^{*}\mathfrak{F}$.
Библиография: 30 названий.
Benefits of Early In-Hospital Antivenom Administration to Patients with Protobothrops mucrosquamatus Envenomation
Authors: Chuang Po-Chun , Chang Kang-Wei , Cheng Shih-Yu , Pan Hsiu-Yung , Huang Kuo-Chen , Huang Yii-Ting , Li Chao-Jui
Published: November 2020

Protobothrops mucrosquamatus is one of the common venomous snakes in Southeast Asia. This retrospective cohort study conducted in six medical institutions in Taiwan aimed to obtain information on the optimal management strategies for P. mucrosquamatus snakebite envenomation. Data were extracted from the Chang Gung Research Database from January 2006 to December 2016. The association between early antivenom administration and patient demographics, pain requiring treatment with analgesic injections, and hospital length of stay was analyzed. A total of 195 patients were enrolled; 130 were administered antivenom within 1 hour after emergency department arrival (early group), whereas 65 were treated later than 1 hour after arrival (late group). No in-hospital mortality was identified. The difference in surgical intervention rates between the early and late groups was statistically insignificant (P = 0.417). Compared with the early group, the late group showed a higher rate of antivenom skin test performance (46.9% versus 63.1%, respectively, P = 0.033), longer hospital stay (42 ± 62 hours versus 99 ± 70 hours, respectively, P = 0.016), and higher rate of incidences of pain requiring treatment with analgesic injections (29.2% versus 46.2%, respectively, P = 0.019). After adjusting for confounding factors, early antivenom administration was associated with decreased pain requiring treatment with analgesic injections (adjusted odds ratio: 0.51, 95% CI: 0.260–0.985). Antivenom administration within 1 hour of arrival was associated with a decreased likelihood of experiencing pain and hospital length of stay in patients with P. mucrosquamatus snakebites. Antivenom skin testing was associated with delays in antivenom administration.
Kapadoška grščina
Authors: Janse Mark , Kavčič Jerneja
Published: November 2020

Članek oriše jezikovno in socialno-kulturno zgodovino Kapadokije in Kapadočanov od časov Hetitskega kraljestva v pozni bronasti dobi do izmenjave prebivalstva med Grčijo in Turčijo v letih 1923‒1924. Po izmenjavi prebivalstva so bili Kapadočani diskriminirani zaradi svojega videza, še prav posebej pa zaradi jezika, kar je povzročilo, da so bili vse manj naklonjeni prenašanju jezika na otroke in vnuke. V osemdesetih letih 20. stoletja je pravladalo prepričanje, da je kapadoščina izumrla, vse dokler nista Mark Janse in Dimitris Papazachariou odkrila, da se v Grčiji še vedno do določene mere govori eno od kapadoških narečij. Ko je akademska skupnost prepoznala kapadoščino kot še vedno živ jezik, je to pripeljalo do spremembe negativnega odnosa, ki so ga do materinščine gojili Kapadočani sami. Zgodba o kapadoščini je tako še eno pričevanje o socialno-kulturni vlogi akademskega dela na področju humanistike.
Screening of Twenty-one Ethiopian Medicinal Plants for their Antiproliferative Activity against Human Acute Myeloid Leukemia (MV4-11) Cell Line
Authors: Tesfaye Solomon , Tadesse Solomon , Engidawork Ephrem , Belete Anteneh , Schaufler Katharina , Guenther Sebastian , Asres Kaleab
Published: November 2020

In vitro antiproliferative activities of the 80% methanol extracts of 21 traditionally used Ethiopian medicinal plants were studied using human acute myeloid leukemia (MV4-11) cell line. Among the tested plants, Euphorbia schimperiana Scheele and Gnidia involucrata Steud. ex A. Rich. exhibited  significant antiproliferative activity with GI50 values of 20.6 ± 10.3 μg/ml and 16.6 ± 12.3 μg/ml, respectively. The active extracts were further fractionated using n-hexane, chloroform, ethyl acetate, n-butanol and water, and the antiproliferative assay results indicated that the n-hexane (GI50 = 0.8 ± 0.2 μg/ml) and ethyl acetate (GI50 = 6.1 ± 0.6 μg/ml) fractions of E. schimperiana and G. involucrate, respectively, demonstrated better antiproliferative activity when compared with their respective hydroalcoholic extracts. The findings of this study suggest that further phytochemical studies on the active fractions may lead to the discovery of novel anticancer compounds.

Keywords: antiproliferative activity, Ethiopian medicinal plants, acute myeloid leukemia cell line, Euphorbia schimperiana, Gnidia involucrata
Antidiarrhoeal activity of the 80% methanol root extract of  Thalictrum ryhnchocarpum Dill. & A. Rich and its major constituent against castor oil-induced diarrhoea in mice
Authors: Feyisa Kebede , Bisrat Daniel , Tadesse Solomon , Asres Kaleab
Published: November 2020

No Abstract.
Application of some selected yeasts isolates in bioelectricity generation using Microbial Fuel Cell (MFC)
Authors: Adekanle Margaret. A. , Oloke Julius K. , Adekunle O. Catherine , Oluwakemi Adesiji Y.
Published: November 2020

Power supply has remained a challeng issue in developing coutries. The aim of this study was to evaluate the potentials of selected yeast species for bioelectricity generation. Different yeast species were isolated from cassava wastewater, whey wastewater, human urine, and rabbit dung using the spread plate method. These isolates were identified using analytical profile index (API). Results obtained revealed the identity of the isolated yeast species as Candida famata, Candida hellenical. Candida tropicalis and Saccharomyces cerevisia (using API method).The isolated yeast species were used singly, and as a consortium for bioelectricity generation, and yeast in continuous mode. The same wastes as used for the isolation process were evaluated as possible substrates for the generation of bioelectricity. Out of the four wastes used, cassava processing wastewater gave the  highest bioelectricity potential and was subsequently used as substrate for further study. Saccharomyces cerevisiae elicited the highest electricity generation when the four yeast species were used singly (1.08V). A consortium of the four isolates elicited a synergis effect, generating 1.57V of voltage. Stacking of the Microbial Fuel Cell(MFC) components improved voltage to 2.4V due to its lower internal resistance within the stacked materials. It is apparent from the results obtained in this study that when properly harnessed, microbial fuel cells (MFCs) technology could serve as alternate source of renewable energy.

Keywords: Microbial fuel cells, Waste, yeasts, Salt- Bridge, Nafion117.
Antibacterial Metabolites obtained from fermentation of peanut and cowpea by Lactobacillus spp
Authors: Oyedoh P.O. , Oshoma C.E. , Ikenebumeh M.J.
Published: November 2020

Lactic acid bacteria elective habitat is food matrix, where they release encrypted metabolites from several parent proteins as a result of their proteolytic activity in the matrix. These metabolites when decrypted confer different bioactive activity thus improving public health. This study was aimed at producing peptide containing metabolites with antibacterial efficacy from defatted cowpea and peanut using Lactobacillus spp. Lactobacillus spp. isolated from spoilt yoghurt were identified using culture dependent and independent method. The isolates were screened for proteolytic ability on skimmed milk agar. The selected isolate with highest proteolytic activity was used for metabolites production through fermentation of defatted cowpea and peanut at 37 oC for 72 h. Parameters analyzed during fermentation were pH, Lactobacillus count, protease activity, peptide concentration and antibacterial activity. The crude peptides produced were assayed for antibacterial activity against bacteria isolated from spoilt meat. From the identified Lactobacillus spp., L. plantarum CAU4347 had the highest proteolytic activity with clear zone of 24.50 ± 0.707 mm. During fermentation the highest and lowest Lactobacillus counts were from cowpea and peanut media with values 294.2 ± 0.21 ×107 and 0.60 ± 0.4 ×107 cfu/ml respectively. Cowpea medium inoculated with L. plantarum CAU4347, had the highest peptide concentration of 79.92 ± 0.01 µg/ml. Consequently, peanut medium showed higher antibacterial activity of 18 mm against Escherichia coli. This result finding suggests that encrypted peptide metabolites from cowpea and peanut flour can confer antibacterial activity against meat spoilage bacteria thus could be utilized as a potential bio-preservative.

Keywords: Metabolites, Cowpea, Peanut, Bioactive, Fermentation, Lactobacillus plantarum
Effect of planting date on the growth, fibre and seed yield of Kenaf (Hibiscus cannabinus L) in Ibadan, South Western Nigeria
Authors: Olanipekun S.O. , Togun A.O.
Published: November 2020

Planting of kenaf usually commences from March - April as these months mark the onset of the rainy season in Nigeria. On the contrary, it is now difficult for anyone to predict when rain start due to climatic variation. Hence, field experiments was conducted between 2015 and 2016 to determine the appropriate time of sowing kenaf that will optimize its yield potential in South Western Nigeria. As a result of delay in the commencement of rain, planting did not start until May. Hence, kenaf seeds were sown in May, June, July and August at 30 days interval in each year. The experiment was a 4 × 2 factorial laid out in a randomized complete block design and replicated three times. The result indicated that the highest fibre yield (1.00 t/ha) was from the kenaf sown in June irrespective of the year, but not significantly different from the one sown in July (0.98 t/ha). On the other hand, kenaf sown in July had the highest seed yield (2.28 t/ha) with the lowest seed yield (1.04 t/ha) obtained in May followed by August (1.19 t/ha). The experiment conclusively affirm June for sowing of kenaf for fibre cultivation and July for seed production.

Keywords: Planting date, kenaf, fibre and seed yield
Additive model of aboveground biomass of larch single-trees related to age, Dbh and height, sensitive to temperature and precipitation in Eurasia
Authors: Usoltsev Vladimir А. , Shobairi Seyed Omid Reza , Osmirko Anna. A. , Tsepordey Ivan. S. , Chasovskikh Viktor. P.
Published: November 2020

The first attempt of modeling changes in the aboveground additive component composition of larch (genus Larix spp.) tree biomass, according to the Trans-Eurasian hydrothermal gradients of Eurasia on the database compiled for the structure of harvest biomass in a number of 510 sample trees is fulfilled. The adequacy of the obtained regularities is determined by the level of variability 87-99 % explained by the proposed regression models. For the central territory of European Russia, characterized by the mean annual temperature of January -10 °C and the mean annual precipitation of 400 mm, the increase in temperature by 1°C at the constant level of precipitation causes on Larix spp. trees of the equal age and sizes, the decrease in the aboveground, stem, needle and branches by 0.4, 0.3, 1.4 и 1.3 %, respectively. For the same region, in equal-sized trees, the increase in precipitation by 100 mm at a constant annual temperature in January causes the decrease of the aboveground and stem biomass by 1.2 and 1.7%, respectively, and the increase of needle and branches biomass by 4.0 and 6.0%, respectively. The development of such models for the main forest-forming species of Eurasia will make it possible to predict changes in the productivity of the forest cover of Eurasia in connection with climate change.

Keywords: larch trees, genus Larix spp., tree biomass, allometric models
The characteristics analysis of strain variation associated with Wenchuan earthquake using principal component analysis
Authors: Zhu Kaiguang , Chi Chengquan , Yu Zining , Fan Mengxuan , Li Kaiyan , Sun Huihui
Published: November 2020

Borehole strainmeters that are installed deeply into bedrock are capable of recording both continuous stress and strain measurements, and have consequently become an important tool for monitoring crustal deformation. A YRY-4 borehole strainmeter installed at the Guza Station recorded anomalous changes in borehole strain data preceding the Wenchuan earthquake on May 12, 2008 (UTC) (=8.0). We apply principal component analysis (PCA) to analyze borehole strain data from the Guza Station. The first principal component eigenvalues and eigenvectors are calculated. The fitted results of the cumulative number of anomalous eigenvalues demonstrate that an acceleration occurred approximately 4 months before the earthquake (from January 2008). The results of the combined eigenvalue and eigenvector analyses show that the spatial distribution of eigenvectors and accelerated occurrence of eigenvalue anomalies represents the stress evolution characteristics of the fault from a steady state to a sub-instability state in rock experiments. We tentatively infer that this process may also be linked to the preparation phase of a large earthquake.
Dinâmica na produção habitacional urbana pelo estado: reflexões sobre a formação do espaço
Authors: Schmidt Lisandro Pezzi , Silva Márcia da
Published: November 2020

As múltiplas estratégias visando à produção habitacional social e de mercado alteram a estrutura funcional e também social do espaço urbano. As articulações dos promotores imobiliários, o movimento do Estado e a demanda crescente pelas unidades, além de ampliar os negócios imobiliários, mediante espaços para circulação do capital, desperta a necessidade da reflexão sobre os interesses onde se localizam os empreendimentos. Este texto tem como objetivo refletir como o movimento e a produção favorecem a formação de espacialidades no âmbito do Programa Minha Casa Minha Vida/PMCMV. Para fundamentar a análise foram estabelecidos argumentos pela combinação de fontes diversas, sistematizadas de forma a haver o cruzamento das contribuições teóricas, da observação em campo e das informações derivadas dos empreendimentos da Faixa 1 no PMCMV. O recorte territorial, configurado pelas cidades de Guarapuava, Londrina e Ponta Grossa, no Paraná, tem por fundamento a lógica do mercado, acentuando a fragmentação e a segregação socioespacial, resultante da produção de novas espacialidades no contexto da produção de habitações em setores na cidade pouco procurados pelo mercado imobiliário, incentivando, assim, o processo de periferização da produção. Cumpre observar que o artigo tem por finalidade contribuir para a verticalização de estudos sobre as cidades médias e pequenas, permitindo acompanhar e atualizar discussões sobre as políticas públicas setoriais, bem como servir para avaliar a estrutura e a gestão municipal e a função social da cidade.
АСҚАР АЛТАЙ ШЫҒАРМАЛАРЫНДАҒЫ ТӘУЕЛСІЗДІК КӨРІНІСІ
Authors: Мубарак Н. Е. , Керімбекова Б. Д.
Published: November 2020

This article’s key feature is the idea independence being observed from different perspectives in the work of Askar Altay. It is important to discuss and analyze his work in order to understand the significance of Kazakh prose in the years of gaining independence. To what extent Askar Altay is devoted to his creation and what role the independence has: all this can be answered by analyzing his work. Askar Altay has left the invaluable work about the relationship of the individual and the society and has pointed out important things as well.
PENGARUH KECERDASAN EMOSIONAL TERHADAP PERILAKU MENYIMPANG REMAJA DI DESA SILAM KECAMATAN KUOK KABUPATEN KAMPAR
Authors: Ilyas Muhammad ilyas , Azizah Dea Nurul
Published: November 2020

This study discusses emotional intelligence for adolescents in Silam Village, Kuok Subdistrict, Kampar District. The purpose of this study was to study how emotional intelligence on families in Silam Village, Kuok District, Kampar District. The type of research used is descriptive quantitative research. The population subjects were 250 teenagers in Silam Village and a sample of 71 adolescent Cluster Random Sampling. The technique of collecting data using a questionnaire with a Likert scale. The data analysis technique in this study was carried out by simple linear regression analysis, and the processing in this study used the SPSS version 17.0 (Statistical Products and Services Solution) program for windows. The results showed a significant influence between emotional intelligence on adolescent behavior in the Silam Village, Kuok Subdistrict, Kampar District. Based on the hypothesis test (Significant Test), the Probability value of α is 0.05 ig sig (0.05 ≥ 0.00) which means Ha is accepted and Ho is rejected. Thus it can be denied that emotional intelligence is approved of adolescent behavior.
Spatial-Temporal Analysis the Dynamics of Changes on the Foreign Exchange Market: an Empirical Estimates from Ukraine
Authors: Vasiurenko Oleg , Lyashenko Vyacheslav , Baranova Valeria , Deineko Zhanna
Published: November 2020

The foreign exchange market plays an important role in the formation and development of financial markets. This market is of particular importance for emerging economies. To understand market trends (to understand and develop a strategy for its development), it is necessary to analyze historical data. It is also important to use different methods to carry out this analysis. Based on this, the paper analyzes the foreign exchange market in Ukraine for the period 2014-2018. For this analysis, the wavelet coherence methodology is used. This made it possible to assess the development of the foreign exchange market in Ukraine.
The Effect of Substitution, Augmentation, Modification and Redefinition Model on Students’ Writing Skills
Authors: Binangbang Jhurica
Published: November 2020

Purpose: This study aimed to determine the effects of Substitution, Augmentation, Modification and Redefinition (SAMR) Model on Danao National High School Grade 12 students’ writing skills. Specifically, it sought to determine if SAMR Model could enhance the writing skills of students.

Approach/Methodology/Design: The study only covered the writing skills which include ideas, organization, word choice, sentence fluency and convention (grammar and mechanics). The written outputs, specifically the rationale, significance of the study and scope and delimitation from the students’ Practical Research 2 subject were the bases for the experimentation. The study utilized quasi-experimental method to determine the effectiveness of Substitution, Augmentation, Modification and Redefinition Model as the basis for technology integration on enhancing the students’ writing skills. This study used the researcher-made pre-test and post-test questionnaire and raters were chosen to evaluate students’ outputs.

Findings: It was found out that the level of the writing skills of the control and experimental groups did not change on their pre-test and post-test. Both groups showed an increase on their post-test results. The results of the experimental group indicated that SAMR Model has improved students’ writing skills

Practical Implications: The utilization of this model on writing activities or subjects will likely create a new field of interest and widen students’ perspectives on the different means or medium of writing. However, this tool would really take much time, effort and technological skills on the part of the facilitator to make it as effective as possible.

Originality/value: This study proposed Action Program to Improve Writing Instruction in Danao National High School.