bluuebunny/crossref_metadata_2025 huggingface dataset:
Traumatic posterior dislocation of hip with ipsilateral fracture of shaft of the femur: external maneuvers reduction and osteosynthesis by screw plate about a case and review of literature at Tambacounda regional hospital in Senegal
Authors: Sidibe Mohamed , Bah Mohamed Lamine , Sylla Fodé Mahamoud , Camara Minkailou , Soumah Alhassane , Ntungwanayo Serge
Published: August 2022

Traumatic hip dislocation associated with an ipsilateral femoral fracture is a rare injury. It occurs in a high-energy traumatic context. The classic mechanism consists of a fall with landing on the hip, which initially dislocates and the femur fracture occurs secondarily by adduction of the proximal fragment. The diagnosis is difficult in front of the fracture whose signs mask the vicious attitude of the dislocation. We reported the case of a passenger of a motorcycle who collided with a parked car.  He was ejected from the motorcycle and landed on his right hip. We performed X-rays of hip and lower limb at his admission which revealed a dislocation of hip in its high posterior variety and a medio-diaphyseal fracture of femur on same side. Reduction of dislocation by external maneuvers was made and osteosynthesis of femur with screwed plate performed 48 h later. After 16 months of care, functional and radiological results sufficient.
A histopathological study of spectrum of splenic lesions- An eleven year analysis of clinical and pathological aspects of splenectomy specimens in a tertiary care hospital
Authors: Namratha R  , Vijaya B  , Bhadran Karthika
Published: August 2022

: The spleen is the largest organ in the mononuclear phagocytic system which plays a prominent role in systemic inflammation, hematopoietic disorders, and metabolic disturbances. Our limited understanding of the pathological processes in the spleen is due to the recent changing trends in the indications for splenectomy and the limited number of splenectomy specimens available for examination. Splenectomies are rarely performed for diagnostic purposes and are usually done as a therapeutic procedure.

The aim of the study is to analyse the etiological factors responsible for splenectomy and correlate factors such as age, sex and indications with macroscopic and histopathogical features in splenectomy specimens.

: The present study is retrospective in nature and studies the histomorphological patterns in 68 splenectomy specimens received at the department of pathology at a single tertiary care center in Southern India.

: It was found that the male: female ratio was 1.4:1. The age of patients ranged from 6 to 75 years and the mean age was 37 years. Traumatic injury was found to be the most common indication for splenectomy (32.35%) followed by hypersplenism and portal hypertension. Congestive splenomegaly was the most common pathology in the specimens studied while a few rare incidental lesions were encountered.

: This study reflects the current trends in the indications and surgical pathology of splenectomy specimens in a tertiary care teaching center.The indications for splenectomy correlated well with the histological findings.
Role of HER2/neu expression in premalignant and malignant lesions of uterine cervix
Authors: M Vijayalakshmi  , Thilagavathy N Sharmila , Rani K
Published: August 2022

Many research studies on various biomarkers were done, in analysing the prognosis and in evaluation of therapeutic target strategies which improves the survival rate in carcinoma of cervix. Of these, one of the important biomarker is HER-2/neu.

To correlate histomorphology of cervical lesions, various clinicopathological parameters with HER-2/neu.

The present study conducted during the period from June 2017 to May 2019 in department of Pathology, Madurai Medical College, Madurai. 200 cases were selected for study. Among those, 50 cases were selected for immunohistochemical studies with HER 2.

Out of 50 cases included, higher HER 2 positivity was observed in HSIL as compared to LSIL. In malignant lesions, positive immunostaining was observed in 71.05% cases. Positivity was seen in 70% of cases of squamous cell carcinoma and 75% of cases of adenocarcinoma cases.

Progression of clinical spectrum of the lesion is associated with overexpression if HER 2, suggesting HER 2 can be considered as one of poor prognostic factor. Malignant lesions expressed greater positivity than premalignant lesions. Also, overexpression of HER 2 is associated with progressing grade and advanced stage of cervical carcinoma.
Comparing the efficacy of xylene and kerosene oil as a clearing agent during processing and staining in histopathology
Authors: Singh Manbeer , Singh Amit Kumar , Kaur Jappreet
Published: August 2022

Aim of this study is to determine the efficacy of kerosene oil as a clearing agent for tissue processing, haematoxylin & Eosin stains in contrast with traditionally used xylene. The study was conducted using three types of clearing agents xylene, kerosene and mixture of xylene kerosene oil in the ratio 50:50. Hundred cases of biopsies for each clearing agent were compared on the basis of ribboning, thin section, section cutting, nuclear staining, cytoplasmic staining, differential staining, clarity and uniformity of the tissue sections. Biopsy specimen was received in the Department of Pathology G.G.S Medical College and Hospital. The investigation of all cases was compared by using the routine method of histopathology lab. Results related to the tissue processing, section cutting and staining were obtained after the microscopy investigation by the residents. The xylene processed tissue produced better thin sections and ribboning during section cutting than those processed in mixture of kerosene and xylene and kerosene alone being the least suitable agent in case of thin section cutting. The nuclear staining, cytoplasmic staining and Differential were better processed in xylene than those processed in mixture of kerosene and xylene and kerosene alone. The clarity and uniformity was not satisfactory by using the mixture of kerosene and xylene while kerosene alone than xylene processed tissues.
Resenha crítica do livro “A batalha dos poderes: da transição democrática ao mal-estar constitucional” de Oscar Vilhena Vieira
Authors: Lins de Araujo Tatyanne Maria
Published: August 2022

A presente resenha crítica faz uma análise da relação entre os Poderes Legislativo, Executivo e Judiciário no atual cenário brasileiro, associando o livro com outros autores que debatem a temática. É possível observar uma interferência e desequilíbrio no exercício de suas funções, dando destaque ao protagonismo judicial, que por vezes pode se considerar sua atuação além do limite democrático, consequência do momento de crise política que perdura no presente momento.
La inteligencia artificial y la tecnología robótica como categorías jurídicas
Authors: Banchio Pablo Rafael
Published: August 2022

El autor plantea el desafío de la regulación jurídica de las relaciones en el ámbito de la inteligencia artificial y la tecnología robótica en el contexto actual de la situación. Como hipótesis sostiene la posible atribución de una personalidad especial en lugar de analogarlas a la normativa existente. El problema de investigación plantea determinar a que categoría y dentro de que ámbito legal debe establecerse ese atributo particular de personalidad. Para ello analiza a) los diversos sistemas virtuales estableciendo las diferencias entre robótica e inteligencia artificial y luego las distintas formas y clasificaciones de la inteligencia artificial y, b) la normativa inicial de derecho indicativo existente en el ámbito internacional y especialmente los aspectos éticos de la misma. Concluye que la estrategia jurídica exige el rediseño de la Teoría General para no seguir anclada al pasado y postula un estatuto jurídico del ciberujeto de carácter anticipatorio universal-total tanto legal, como técnico de los fundamentos y de las condiciones del desarrollo, lanzamiento, funcionamiento e integración con otros sistemas para armonizar así completamente la robótica y la inteligencia artificial al juego de la vida humana.
El control judicial de la actividad administrativa automatizada
Authors: MuÃ±oz Ricardo A.
Published: August 2022

En un contexto de crisis sanitaria -todavía vigente-, en donde las organizaciones debieron acelerar exponencialmente sus procesos de transformación digital, y las administraciones públicas en particular, debieron transitar hacia caminos trazados en la apertura de datos por diseños y procesos gubernamentales centrados en la información, lo que llevó incluso a la utilización de técnicas de Inteligencia Artificial para el sector público, el presente trabajo busca responder al elemental interrogante respecto ¿Qué debe controlarse judicialmente en el caso de la actividad decisional administrativa automatizada? O si se prefiere ¿Qué principios debe respetar la Administración pública, de verificación por el Poder Judicial, cuando se sirve de herramientas inteligentes para el cometido de sus funciones? Así es que el trabajo ofrece -en términos generales- una serie de herramientas evaluativas que debe tener a la vista el magistrado para convalidar, o en su caso, invalidar una actuación decisoria de este tipo.
A cidadania ativa dos idosos e as universidades da terceira idade no cenário internacional
Authors: Thomé Mariana Teixeira
Published: August 2022

O trabalho pretende abordar a correlação entre o exercício da cidadania ativa dos idosos e as Universidades da Terceira Idade. Analisa-se o que é cidadania, seu exercício ativo pelos cidadãos idosos, a educação atrelada a ela e as Universidades da Terceira Idade em âmbito internacional. A finalidade do trabalho é demonstrar de que forma essas universidades capacitam e corroboram o exercício da cidadania dessas pessoas. Demonstram-se, também, as diferentes formas com que essas universidades tratam a temática em seus programas. Percebe-se que as Universidades da Terceira Idade muito contribuem para o exercício da cidadania dos idosos na medida em que os capacita para tanto por meio das aulas e cursos disponibilizados. Esses permitem a ampliação do conhecimento e a troca de experiências de modo que toda a sociedade é favorecida com o compartilhamento de conhecimentos. O lapso temporal da pesquisa é o cenário atual de desenvolvimento da cidadania e a análise dos currículos das universidades ao longo da década de 1990 até o início dos anos 2000. A metodologia adotada é descritiva, documental e bibliográfica. Recorre-se a textos de autores que fazem um estudo analítico sobre a temática (em livros, artigos e dissertações) bem como a documentos legais e revistas da Organização das Nações Unidas, da Organização Mundial da Saúde e da Association Internationale des Universites du Troisième Age.
Visión sistémica de la transferencia de conocimiento y tecnología en la universidad
Authors: Bermeo Giraldo María Camila , Villalba Morales María Luisa , Ruiz Castañeda Walter Lugo
Published: August 2022

El proceso de transferencia de conocimiento y tecnología en la Universidad requiere ser analizado desde una perspectiva dinámica, al reconocerse como un sistema complejo que proporciona capacidades que mejoran el desempeño de cara a la competencia, que permitan la circulación de las innovaciones y generen valor para la industria. Esta investigación tuvo como objetivo producirar una visión sistémica del proceso de transferencia de conocimiento y tecnología en la universidad. Para ello se utilizó la dinámica de sistemas como herramienta metodológica y para la validación se empleó el caso de estudio de la Facultad de Minas de la Universidad Nacional de Colombia. Se plantearon tres escenarios para evaluar el efecto de la disminución del presupuesto, el rápido aprendizaje y el número de estudiantes y docentes dedicados a investigar sobre el proceso de transferencia. Se obtuvieron resultados a partir de la realidad de la Universidad Nacional; sin embargo, estos resultados son válidos para otras universidades porque revelan que las capacidades del proceso son sensibles al presupuesto destinado para ellas. Se concluye que la simulación de escenarios sirve para identificar las características y combinaciones que podrían potenciar la acumulación de activos de conocimiento y tecnología, de aprendizaje del proceso y de las capacidades de transferencia tecnológica en la universidad.
Efﬁcacy of glucose transporter inhibitors for the treatment of ERRα-overexpressed colorectal cancer
Authors: Zhao Miao , Xu Cairong , Zhu Hui
Published: August 2022

Background: Colorectal cancer is the most-incidence associated extremely high mortality rate worldwide. The overexpression of estrogen-related receptor α (ERRα) is contributing to a poor prognosis. Obtaining a better understanding of the mechanisms of ERRα in colorectal cancer is important for developing cancer therapies. Methods: Western blotting and qRT-PCR were used to determine the protein and mRNA levels of ERRα, OUTB1, and solute carrier family 7 member 11 (SLC7A11) in HCT-116 cells. Short hairpin RNA (shRNA) was used to knockdown ERRα in HCT-116 cells. The level of reactive oxygen species (ROS), the nicotinamide adenine dinucleotide phosphate NADP+/NADPH, and the oxidized glutathione (GSSG)/reduced glutathione (GSH) ratio were measured by HPLC-MS to determine the redox state in HCT-116 cells. Lastly, tumor xenograft experiments were carried out to determine the effect of glucose transporter (GLUT) inhibitor. Results: Knockdown of ERRα decreased the expression of OTUB1 and SLC7A11 in HCT-116 cells. SLC7A11 overexpression induced NADPH-dependent redox system collapse. Aberrant expression of ERRα significantly reduced NADPH level and resulted in collapse of the redox system under glucose deprivation. Furthermore, ERR overexpression of ERRα sensitized cancer cells to inhibition of GLUTs. Treatment with GLUT inhibitor significantly reduced tumor volume after 6 weeks of tumor xenograft experiment. Our study demonstrates that the over-expression of ERRα causes redox system collapses via regulating the expressions of OUTB1 and SLC7A11. Conclusion: Up-regulation of SLC7A11 mediates the disruption of cell metabolism and the balance of redox state in colorectal cancer. Additionally, the GLUT inhibitor significantly reduces colorectal tumor volume, suggesting that the GLUT inhibitor could serve as a potential therapy for colorectal treatment.
Vpliv podnebnih sprememb na gnezdenje obrežnih ptic
Authors: Ivajnšič Danijel Ivajnšič , Škornik Iztok , Kaligarič Mitja , Lipej Lovrenc
Published: August 2022

Podatki 6. poročila IPCC nakazujejo še intenzivnejši trend dviga morske gladine v drugi polovici stoletja. Piranski zaliv bi lahko bil v primeru uresničitve pesimističnih napovedi (ssp585) izpostavljen dvigu morske gladine tudi za 120 cm (v primerjavi z obdobjem 1995–2014). Nedvomno bodo zaradi tega prizadeta nizko ležeča obalna mokrišča in nanje vezani organizmi. Obrežne ptice (še posebej gnezdilke) bodo, zaradi visokega položaja v prehranjevalnem spletu obmorskih mokrišč, prvi pokazatelj okoljskih sprememb. V raziskavi obravnavamo odziv štirih vrst obrežnih ptic, kot so polojnik (Himantopus himantopus), beločeli deževnik (Charadrius alexandrinus), navadna (Sterna hirundo) in mala čigra (Sternula albifrons), na dvosmerni okoljski pritisk (dvig morske gladine in širjenje antropogenih dejavnosti) v Krajinskem parku Sečoveljske soline (KPSS). Oceno potencialne spremembe gnezditvene površine ptic zaradi dviga morske gladine smo izračunali na podlagi modelov razširjenosti vrst (Mahalanobisova tipičnost in Maxent). Ugotovitve kažejo, da se bosta beločeli deževnik in polojnik v KPSS kmalu soočila z zmanjšanjem potencialne gnezditvene površine, medtem ko so napovedi za obe vrsti čiger manj dramatične. Odkrit individualistični odzivi preučevanih vrst ptic na dvig morske gladine kot posledice podnebnih sprememb je lahko pomembna informacija za varstvene biologe v zavarovanih območjih, ki pripravljajo načrte za ublažitev negativnih vplivov na zavarovane habitate.
О некоторых ошибках в переводе с русского на болгарский язык (на материале переводных статей общественно-политического характера)
Authors: Иванова Ваня
Published: August 2022

Статья рассматривает некоторые ошибки в переводе с русского на болгарский язык материалов общественно-политического характера. Цели исследования: выявить причины возникновения переводческих ошибок и определить самые распространенные типы ошибок в соответствии с требованиями к адекватности перевода, принятыми в русской транслатологии. Методом исследования служит сопоставительный анализ перевода – анализ формы и содержания текста перевода в сопоставлении с формой и содержанием текста оригинала. В качестве основы систематизации обнаруженных ошибок используются два типа классификации. Первая из них базируется на причинах их возникновения и выявляет уровни в переводческом процессе, на которых происходят ошибки. Во второй классификации ведущими являются степень искажения оригинального текста и специфика ошибок в переводе. В этом плане выделяются разные виды содержательных несоответствий: немотивированные добавления или опущения, неудачные формулировки, непереведенные единицы, «ложные друзья переводчика», нарушение общей, предметной или текстовой логики и т.д. В результате проведенного анализа устанавливается, что в основном допущены ошибки на уровне знак – понятие, преимущественно из-за непонимания смысла слов в оригинале; наблюдаются также ошибки на этапе перевыражения системы смыслов, по причине недостаточно мастерского владения переводчиками как языком оригинала, так и языком перевода. На материале рассмотренных переводных статей самыми распространенными оказываются ошибки классификационных типов искажения и неточности.
Інтэрпрэтацыя гемеронімаў у лінгвістычным дыскурсе
Authors: Лухверчык Вікторыя
Published: August 2022

У артыкуле аналізуюцца ўсходнеславянскія лінгвістычныя даследаванні, прысвечаныя рознааспектнаму апісанню гемеронімаў. Мэта даследавання – акрэсліць месца гемеронімаў у лінгвістычнай літаратуры, разгледзець погляды лінгвістаў адносна наяўнасці / адсутнасці семантыкі ва ўласных імёнах, вызначыць прыярытэтныя вектары ў даследаванні назваў перыядычных выданняў, тэле- і радыёперадач. У працы адзначаецца, што аналіз назваў перыядычных выданняў, тэле- і радыёперадач ў беларускім мовазнаўстве абмяжоўваецца адзінкавымі артыкуламі (Л.А. Гадуйка, В.Г. Сцеранчук, В.А. Зразікава, У.А. Сцяпанаў). Ва ўсходнеславянскай лінгвістыцы фіксуюцца асобныя манаграфічныя даследаванні, аб’ектам вывучэння ў якіх з’яўляецца названы тып онімаў (працы М.А. Драгайцавай, М.С. Дуднікавай, Т.І. Кравец, Л.Р. Мухаметзянавай, М.М. Сулейман). У дадзеным артыкуле выкарыстоўваюцца апісальны метад сінхроннага аналізу з элементамі дыяхраніі, а таксама параўнальна-супастаўляльны метад. Зроблена выснова, што ў сучаснай лінгвістычнай навуцы адзначаецца пэўная цікавасць аўтараў да вывучэння гемеронімаў, што абумоўлена павышэннем ролі сродкаў масавай інфармацыі ў жыцці грамадства, аднак да гэтага часу не вырашана пытанне аб адсутнасці / наяўнасці семантыкі ва ўласных імёнах і канчаткова не вызначана месца гемеронімаў у анамастычнай сістэме. Вынікі даследавання могуць быць выкарыстаны пры далейшым даследаванні праблем усходнеславянскай анамастыкі.
L’Aromathérapie au temps de la « peste » en France (XVIe-XVIIe siècles)
Authors: Koźluk Magdalena
Published: August 2022

Historians of medicine often write of “the psychosis” and “the omnipresent fear” that, in the Middle Ages, paralyzed the whole European population, due to the many mysteries that surrounded the plague, its origin, its inexplicable recurrence and its nature. These mysteries led to an abundance of treatises on the plague written in Latin as well as in the vernacular, which appeared in the XVIth and XVIIth centuries in France. Their authors, physicians, barber-surgeons and apothecaries, advanced theories and proposed efficient prophylactic treatments. Our research is principally concerned with the status of the proposed remedies, in particular on the importance of their aromas. We first consider the role assigned to the quality of the air (climate, home), to its alterations and to the best means of improving it (fumigation, incense). We then examine the aromatic composition of the remedies proposed, focusing on their forms and uses.
Le personnage houellebecquien dans le monde décadent
Authors: Modrzejewska Krystyna
Published: August 2022

Michel Houellebecq in his novels “Platform” (2001), “Map and territory” (2010) and “Submission” (2015) shows the struggles of a man trying to find his place in the modern world. Author’s alter egos – writer, painter, clerk of the Ministry of Culture, researcher in literary studies, witness a deep crisis that heralds the end of Europe. Unbridled consumption, clumsy journalists, crisis of democracy and Church’s institution are leading to the collapse of the old world. The prospect of being absorbed by Muslims, led by an extremely skilled politician, confirms Houellebecq’s talent, arousing anxiety and opposition.
Enjeux littéraires, bibliques et rhétoriques dans le discours liminaire des épopées apocalyptiques renaissantes
Authors: Krawczyk Dariusz
Published: August 2022

The aim of this article is to analyse the prefaces to the French Renaissance apocalyptic epics of the years 1576-1606 (works by Jacques de Billy, Guillaume de Chevalier, Michel Quillian and Jude Serclier) in order to understand the literary and extra-literary issues addressed by their authors. This comparison will highlight in particular the ethos of the author, the problem of representation in a biblical poem and its eschatological dimension, the place of pagan fiction and encyclopaedic erudition, and the rhetorical strategies employed.
La post-mémoire et le problème de l’identité nationale et individuelle présentés dans la littérature mauricienne contemporaine d’expression française
Authors: Szkonter-Bochniak Anna
Published: August 2022

In the article the author analyses the influence of post-memory in the formation of national and individual identity among the inhabitants of the young Republic of Mauritius presented in contemporary Mauritian literature in French. Important and at the same time tragic historical events of Mauritius are: slavery, the arrival and labour of indentured workers from India and the tragedy of the Chagos Islanders. The author analyses some texts by Ananda Devi and Shenaz Patel in which both writers describe the impact of ancestral history on the lives of characters representing the next generation from different ethnic groups living on the island. In her analysis, the author refers to the works of Marianne Hirsch, Paul Ricoeur and Alex Mucchielli.
Préface. L’art de vivre, de survivre, de revivre. À l’occasion du 50e anniversaire des études romanes à l’Université de Łódź
Authors: Kacprzak Alicja
Published: August 2022

Cette préface présente le volume L'art de vivre, de survivre, de revivre. À l'occasion du 50e anniversaire des études romanes à l'Université de tódž qui a été conçu pour commémorer le 50e anniversaire de la réactivation des études romanes à l'Université de Lódž, menées aujourd'hui au sein de l'Institut d'Études Romanes. En même temps, l'ouvrage célèbre le loe anniversaire de la création, au sein de l'Institut d'Études Romanes, du Département de Philologie Italienne. Ces anniversaires ont lieu au moment de la pandémie du Covid-19, événement sans précédent dans le monde global du 21e siècle, avec le confinement en tant que mode de fonctionnement obligatoire pendant de longues semaines, voire des mois. La rupture ainsi opérée a sans doute entraîné une nouvelle perception de la vie et de ce que représente le fait de vivre. Pour plus d'un, cette tracé épaisse qui sépare notre existence d'avant et d'après le Covid-19 constitue un memento incitant à se demander comment vivre la pandémie et pendant la pandémie, comment y survivre et s'il est possible de (re)vivre totalement quand elle aura pris sa fin. Ces questions lancées comme le thème conducteur du volume de commémoration ont appelé une réflexion riche et variée contenue dans 25 articles, s'inscrivant dans différents sous-domaines de la linguistique.
À propos des noms d’épidémies
Authors: Bochnakowa Anna
Published: August 2022

L’article est une présentation de noms français et polonais que l’on utilisait couramment pour désigner les maladies contagieuses qui décimaient la population de l’Europe à travers les siècles. Entre l’Antiquité et le XXIe  siècle, l’Europe a connu plusieurs épidémies : peste, rougeole, dysenterie, variole, choléra, lèpre, tuberculose, maladies vénériennes, grippe et ses variantes et autres maladies jusqu’au Covid-19 de notre temps, deviennent un élément de la réalité commune et pour cette raison aussi de la langue. On montre le mécanisme de la création de noms d’épidémies et l’on retrace l’origine et l’histoire de ceux-ci en français et en polonais. On souligne les ressemblances et les différences dans la dénomination des épidémies étant une expérience commune.
Équivalents polonais du verbe vivre dans le corpus parallèle français-polonais
Authors: Cholewa Joanna
Published: August 2022

Le présent article vise à analyser la plurivocité sémantique du verbe vivre dans le Corpus Parallèle de Textes Littéraires, composé de documents littéraires français et de leurs traductions en polonais, ainsi que l'hétérogénéité de ses équivalents dans la langue cible. La richesse sémantique de vivre est mise en évidence selon les dix-sept emplois que le dictionnaire Les verbes français propose pour ce verbe. L'objectif de l'analyse est de préciser : (a) lesquels des emplois de vivre sont statistiquement les plus significatifs ; (b) quelles stratégies verbales ou autres sont utilisées pour traduire les occurrences avec différentes emplois de vivre. 
L'analyse met en évidence quatre emplois de vivre : 'être vivant', 'habiter', 'endurer' et 'avoir un tel mode de vie'. Parmi leurs équivalents, il y a non seulement żyć, mais aussi mieszkać, ainsi que les dérivés préfixaux de żyć, dont le fonctionnement devrait être précisé par les dictionnaires.
Discapacidad y pandemia : estrategias publicitarias en un estado de alarma
Authors: Fuentes Rodríguez Catalina
Published: August 2022

Podczas pandemii spowodowanej przez Covid 19 stan zagrożenia w Hiszpanii przeniósł punkt ciężkości w reklamie na ochronę zdrowia własnego i pozostałych członków społeczeństwa. Jednak według fundacji ONCE osoby niepełnosprawne nie były brane pod uwagę w tej trudnej sytuacji. Zostało to potępione w filmie, który wykorzystuje pośrednie procedury, takie jak metaforyzacja, ironia i humor. Podstawowa krytyka konfrontuje się z toposem, który w tym historyczno-społecznym momencie wydaje się zmieniać, przynajmniej pod względem wagi nadanej mu przez społeczeństwo. Wymaga to od Fundacji ONCE dobrania tonu wypowiedzi tak, aby nie wywoływać niepożądanych reakcji. Zabawne ramy (gracze) są tworzone w celu maskowania lub łagodzenia krytyki społecznej i ideologicznej. Emocje chociaż nadal wydają się niepożądane, stają się w nowym kontekście użycia argumentem legitymizującym. Praca składa się z analizy argumentacyjnej (Anscombre-Ducrot 1983) dyskursu multimodalnego, zgodnie z metodologią językoznawstwa pragmatycznego (Fuentes Rodríguez 2017 [2000]).
La transcreazione di pubblicità per il marketing internazionale come un modo di rivivere il testo originale
Authors: Księcikowska Magdalena
Published: August 2022

W artykule omówione zostało zjawisko transkreacji, metody tłumaczenia stosowanej w branży reklamowej jako jednego z etapów tworzenia międzynarodowej kampanii reklamowej. Transkreacja jest czymś pomiędzy tłumaczeniem a tworzeniem tekstu od podstaw, więc wydaje się idealnym sposobem, by dać tekstowi oryginału drugie życie w nowej wersji w języku docelowym. Polega na adaptacji oryginalnego przekazu reklamowego w celu uzyskania równoważnej reakcji ze strony odbiorców docelowych, z uwzględnieniem intencji nadawcy, niuansów społecznych i kulturowych, a także cech języka przekładu oraz nawyków konsumpcyjnych charakterystycznych dla rynku docelowego. Jest to metoda pozwalająca na zachowanie intencji tekstu oryginalnego, przy jednoczesnym wykorzystaniu kreatywnych sposobów na stworzenie autentycznego i przekonującego przekazu w języku przekładu skierowanego do odbiorców z innego kręgu kulturowego, niż ten właściwy oryginałowi.
Nuevas estrategias de comunicación en tiempos de COVID-19 para la enseñanza / aprendizaje de la lengua francesa
Authors: Planelles Iváñez Montserrat , Sandakova Elena
Published: August 2022

La pandemia ha ocasionado un cambio radical en la situación educativa a todos los niveles, a la que hemos tenido que adaptarnos bruscamente tanto los docentes como los discentes. La carga emocional que ha supuesto esta pandemia se suma a todas las dificultades materiales y comunicativas que se han derivado de los estados de alarma que se han producido en todos los países a nivel mundial. Así pues, los factores afectivos que intervienen normalmente en el proceso de enseñanza/aprendizaje, contemplados en el MECR en la “competencia existencial” se han puesto especialmente de manifiesto en esta dura etapa en la que el miedo, la incertidumbre y el aislamiento han estado presentes en todas nuestras actividades. En este contexto, el paso de la enseñanza presencial a la enseñanza dual y virtual ha influido negativamente en la motivación no solo del alumnado sino también del profesorado. En este artículo presentamos la experiencia docente de un año en el que la comunicación en el aula entre el profesor y el alumno se ha visto truncada súbita e inesperadamente. Nos basamos en cuatro asignaturas diferentes y alrededor de 200 alumnos. Así pues, establecemos un elenco de problemas detectados en la comunicación dual en el aula y fuera de ella entre el profesor y su alumnado, proponemos alternativas para mejorar la comunicación en el entorno dual en el aula y fuera de ella para suplir las consecuencias negativas de los problemas encontrados e implementamos nuevas estrategias para mantener la atención en clase y así fomentar la motivación.
Le français subjectivement parlant
Authors: Smuk Maciej
Published: August 2022

The main objective of the article is to present the results of some research – carried out with students of French philology in Poland – on their representations regarding to the French language. Some of the aspects will be subjected to a detailed analysis: the feelings that French evokes, its social status, the difficulties identified by the students as the most salient in French learning. All the images, woven by future philologists in their individual productions (and therefore subjective par excellence), allow us to reconstruct the semantic fields specific to the French language.
Comment (se) former à la médiation relationnelle en classe de langue ? Analyse dans l’optique du Cadre européen commun de référence pour les langues: apprendre, enseigner, évaluer. Volume complémentaire avec de nouveaux descripteurs (2018)
Authors: Sujecka-Zając Jolanta
Published: August 2022

We propose to analyze the contribution of the three major works produced by the experts of the Council of Europe and to contribute to a better understanding of the concept of mediation and, in particular, of relational mediation in the language class. Our objective is to follow the terminological and conceptual evolution of the term to arrive at a pedagogical profile of relational mediation that we could then set up in the classroom to ensure genuine language teaching. This analysis stems from the interest attributed to the relational factor following the current COVID-19 pandemic, which has clearly shown the great importance of these questions for educational success.
Argot et gastronomie
Authors: Szabó Dávid
Published: August 2022

Speakers of non-standard varieties of French also like to eat and have their own words for food. But can gastronomy be considered as a major theme in slang? This paper tries to answer this question by analysing argot and unconventional French dictionaries (Colin et al. 2006, Goudaillier 2001, Tengour 2013, Perret 2002) and works by specialists such as Calvet and Robert L’Argenton. Slang varieties dealt with range from traditional French slang to contemporary suburban slang (français contemporain des cités) and include butchers’ slang (louchébem) and bakers’ jargon. The conclusion also suggests some ideas on teaching French as a foreign language.
In vitro sensitivity of Fusarium sacchari isolated from sugar cane to five fungicides
Authors: Medina-Osti Fabiola , Gutiérrez-Díez Adriana , Ochoa-Ascencio Salvador , Sinagawa-García Sugey Ramona
Published: August 2022

The present study had the objective of evaluating the in vitro sensitivity of Fusarium sacchari to five fungicides of different chemical groups. An isolate of F. sacchari obtained from sugarcane plants (Saccharum officinarum) with wilt symptoms and identified morphologically and molecularly by the characteristics of the genus Fusarium and amplification of the ITS and TEF regions, respectively, was used to evaluate the fungicides azoxystrobin, difenoconazole, hymexazole, cyprodinil and thiabendazole, at concentrations of 1, 10, 100 and 1000 ?g mL-1, using the poison plate technique. The effect of the fungicides and EC50 was determined by the percentage inhibition of F. sacchari growth with respect to the growth on the plates without fungicide. The fungicides difenoconazole at 1000 ?g mL-1 and thiabendazole at 100, 1000 and 10 ?g mL-1 were statistically equal and presented the highest mycelial growth inhibition percentages (93.5 and 92.1, 91.4 and 89.8 %, respectively). The lowest EC50 values were presented by difenoconazole (9.2 ?g mL-1), thiabendazole (9.9 ?g mL-1) and cyprodinil (10.6 ?g mL-1). In conclusion, F. sacchari presented higher in vitro sensitivity to the fungicides difenoconazole (1000 ?g mL-1) and thiabendazole (100, 1000 and 10 ?g mL-1).
COVID-19 Health Evidence Summary No.117
Authors: Millington Kerry
Published: August 2022

This weekly COVID-19 health evidence summary (HES) is based on 3.5 hours of desk-based research. The summary is not intended to be a comprehensive summary of available evidence on COVID-19 but aims to make original documents easily accessible to decision-makers which, if relevant to them, they should go to before making decisions. This summary covers publications on Clinical characteristics and management; Epidemiology and modeling; Testing; Therapeutics; Vaccines; Dashboards & Trackers; C19 Resource Hubs and Online learning & events.
Freedoms of expression, political extremism and seditious speech in the United States Supreme Court’s jurisprudence (Part II)
Authors: Machaj Łukasz
Published: August 2022

The article constitutes the second part of a series devoted to analyzing the jurisprudence of the Supreme Court of the United States with respect to the First Amendment’s guarantee of freedom of expression and politically extremist speech. The author discusses the seminal case of Schenck v. United States wherein Justice Oliver Wendell Holmes established the famous “clear and present danger” standard as a means to determine the constitutionality of legislation pertaining to speech. The test allowed for criminalization of expression which had been deemed to cause such a peril. The article analyzes the original meaning of the standard, pointing out its speech-restrictive impact.
Nivel de funcionalidad y calidad de vida en población rural de adultos mayores en un centro integral para el adulto mayor de Lima, Perú.
Authors: Paullo De La Cruz Karen Violeta , Risco Mendoza Genesis Geraldine , Sigueñas Tafur Evelyn Jovanna , González-Farfán María-Eugenia
Published: August 2022

Los cambios morfofisiológicos producidos por el envejecimiento alteran la óptima funcionalidad (autonomía personal) de los adultos mayores menoscabando la realización de sus actividades cotidianas, hecho que repercute en su calidad de vida. Objetivo: Determinar la asociación del nivel de funcionalidad y calidad de vida en adultos mayores del Centro Integral para el Adulto Mayor (CIAM) San Antonio de Huarochirí. Material y Métodos: Estudio observacional, analítico de corte transversal. Se aplicó el Índice de Barthel para medir funcionalidad y el cuestionario SF-36 para calidad de vida. Resultados: Se entrevistó a 156 adultos mayores (AM), predominando el sexo femenino con 61,5%, la edad promedio fue 71,9 años. Los resultados sobre el nivel de funcionalidad mostraron que 0,6% presentó dependencia total, 3,2% dependencia severa, 48.1% dependencia moderada, 15,4% dependencia escasa y el 32,7% con independencia. Respecto a la calidad de vida el 57,1% manifestó tener peor y el 42,9% mejor calidad de vida. Se encontró asociación significativa entre nivel funcional y calidad de vida mediante la prueba chi cuadrado (p < 0,005). Conclusión: El estudio reveló que en los AM del CIAM de San Antonio de Huarochirí predomina la dependencia moderada (48,1%) y que el 42,9% manifestó tener “mejor calidad de vida”; por ello concluimos en que, a mayor nivel funcional, mejor calidad de vida.
Améliorer l’utilisation des graines oléo-protéagineuses par l’extrusion : un enjeu technologique pour contribuer à l’autonomie protéique des élevages bovins laitiers
Authors: NOZIÈRE Pierre , MENDOWSKI Solveig , FERLAY Anne , PEYRONNET Corinne , ENJALBERT Francis , CHESNEAU Guillaume , GERMAIN Antoine , CHAPOUTOT Patrick
Published: August 2022

Dans le but d’assurer une meilleure autonomie protéique pour alimenter les animaux d’élevage, différents leviers, dont le développement de filières de protéagineux à graines, sont envisageables. Le projet Proleval s’inscrivait dans cette perspective. Les effets de traitements technologiques sur la valorisation des graines oléo-protéagineuses par les vaches laitières ont été évalués dans le cadre de ce projet. Une synthèse de la littérature a permis de quantifier l’effet bénéfique quasi-systématique des traitements thermiques ou thermomécaniques des graines sur l’utilisation de l’azote : diminution de la dégradabilité ruminale, augmentation de la digestibilité intestinale, de la fourniture d’acides aminés indispensables, et de la sécrétion de protéines dans le lait. Les effets observés sont toutefois quantitativement variables en fonction des traitements. Les essais expérimentaux conduits dans le cadre du projet ont permis de préciser les effets de certaines modalités d’extrusion des graines de féverole et de lupin : la température d’extrusion et la maturation par des procédés innovants intégrant des sucres réducteurs ou un cocktail enzymatique. Les résultats obtenus par différentes approches (mesures de dégradabilité et de digestibilité in situ, mesures in vivo du bilan azoté chez les vaches laitières) montrent que la température d’extrusion doit être limitée pour éviter une surprotection des protéines et que les prétraitements de maturation testés ne sont pas systématiquement efficaces. Les rares résultats publiés sur la fraction lipidique du lait rapportent une diminution du taux butyreux avec les graines traitées par rapport à la même graine crue. Peu d’études présentent des profils en acides gras du lait, mais les données du projet Proleval indiquent que les graines extrudées favorisent la production d’acides gras trans au niveau du rumen et du lait. La maîtrise des conditions d’extrusion permettant d’aboutir de façon répétable à un produit aux caractéristiques nutritionnelles optimales, qui semble passer par la maîtrise du développement des composés de Maillard, reste un enjeu.
Chronic Positive Mass Balance is the Actual Etiology of Obesity: Time for A Paradigm Shift?
Authors: Manninen Anssi
Published: August 2022

According to known laws of physics, chronic positive mass balance is the actual etiology of obesity, not positive energy balance. The relevant physical law in terms of body mass regulation is the Law of Conservation of Mass, not the Law of Conservation of Energy. A recently proposed mass balance model (MBM) describes the temporal evolution of body weight and body composition under a wide variety of feeding experiments, and it seems to provide a highly accurate description of the very best human experimental feeding data. By shifting to a mass balance paradigm of obesity, a deeper understanding of this disease may follow in the near future. The purpose of this article is to present the core issues of the upcoming paradigm shift as well as some practical applications related to the topic.
Spiropyran/Merocyanine Amphiphile in Various Solvents: A Joint Experimental–Theoretical Approach to Photophysical Properties and Self-Assembly
Authors: Savchenko Vladyslav , Lomadze Nino , Santer Svetlana , Guskova Olga
Published: August 2022

This joint experimental-theoretical work focuses on molecular and photophysical properties of the spiropyran-containing amphiphilic molecule in organic and aqueous solutions. Being dissolved in tested organic solvents, the system demonstrates positive photochromism, i.e. upon UV stimulus the colorless spiropyran form is transformed into colorful merocyanine isomer. However, aqueous solution of the amphiphile possesses a negative photochromism: the orange-red merocyanine form turns to be thermodynamically more stable in water, and both UV and vis stimuli lead to the partial or complete photobleaching of the solution. The explanation of this phenomenon is given on the basis of density functional theory calculations and classical modeling including thermodynamic integration. The simulations reveal that stabilization of merocyanine in water proceeds with the energy of ca. 70 kJ mol−1, and that the Helmholtz free energy of hydration of merocyanine form is 100 kJ mol−1 lower as compared to the behavior of SP isomer in water. The explanation of such a difference lies in the molecular properties of the merocyanine: after ring-opening reaction this molecule transforms into a zwitterionic form, as evidenced by the electrostatic potential plotted around the opened form. The presence of three charged groups on the periphery of a flat conjugated backbone stimulates the self-assembly of merocyanine molecules in water, ending up with the formation of elongated associates with stack-like building blocks, as shown in molecular dynamics simulations of the aqueous solution with the concentration above critical micelle concentration. Our quantitative evaluation of the hydrophilicity switching in spiropyran/merocyanine containing surfactants may prompt the search for new systems, including colloidal and polymeric ones, aiming at remote tuning of their morphology, which could give new promising shapes and patterns for the needs of modern nanotechnology.
Rules of Stochastics of Genomic DNAs, Biological Dualism "Stochastics-Determinism",and Tensor-Unitary Transformations
Authors: Petoukhov Sergey
Published: August 2022

The article is devoted to algebraic modeling of universal rules of stochastic organization of genomic DNA of higher and lower organisms, previously published by the author. The proposed algebraic apparatus, which uses formalisms of quantum mechanics and quantum informatics and which is based on the so-called tensor-unitary transformations of vectors that generate families of interrelated stochastic-deterministic vectors of increased dimensions. The features of the vectors' interconnections in these families model the stochastic-deterministic properties of the named phenomenological rules. There are new approaches to modeling of developing multi-parameter biosystems, whose number of parameters increases in the course of step-by-step development. In the light of the presented materials, the issues of fractal-like organization in genetically inherited biosystems are considered. The development of the theory of stochastic determinism as an antipode of deterministic chaos is discussed.
«Enzymatic Landscape» of the Gut Microbiome in Obese Patients
Authors: Shatova Olga Petrovna , Grigorieva Tatyana Vladimirovna , Appolonova Svetlana Alexandrovna , Makarov Valentin Vladimirovich , Yudin Sergey Mikhailovich , Roumiantsev Sergey Aleksandrovich , Gaponov Andrey Mikhailovich , Shestopalov Alexander Vyacheslavovich
Published: August 2022

Indole and indole-3-lactate are known dominant microbial tryptophan catabolites (MICT). In obesity, the fecal indole concentration corresponds to the normal one, and that of indole-3-lactate significantly decreases along with other MICT, while it increases in blood plasma. During the analysis of the «enzymatic landscape» of the intestinal microbiota we find an almost twofold increase in the correlation between the concentrations of fecal MICT and the «enzymatic landscape», with indole-3-lactate having the closest relationships with the “enzymatic landscape” of all MICT. Here, we report statistically significant correlations of indole-3-lactate and the gut microbial enzymes for fructose, amino sugars, nucleotides, polyamines metabolism, and sulfoglycolysis. We also demonstrate that indole-3-lactate producing microbiota representatives increase three-fold in obesity. The phenotype of the microbiotic population is thus represented by completely different genera and species of microorganisms in obese individuals compared to healthy donors.
Evolution of COVID-19 Spread in the Cohort of LaLiga Football (Soccer) Professionals between May 2020 and April 2021
Authors: Peñuelas Marina , Rojas Ayelen , Guerrero-Vadillo María , León-Gómez Inmaculada , Larrauri Amparo , Prats Francesc , Fuertes Antonio , Zambrano-López Rafael , Ramis Rebeca , Gomez-Barroso Diana
Published: August 2022

Objectives: COVID-19 pandemic interrupted the Spanish professional football competition until May 2020, when it was restarted following a surveillance protocol established by LaLiga. The aims were to describe the infective and serological status of professional football players (PLY) and staff (STF) between May 5th 2020 until April 22nd 2021, to analyze the spatial-temporal distribution of the COVID-19 disease in this cohort and its comparison to the Spanish population. Methods: a prospective observational cohort study was carried out. Differences between PLY and STF were assessed by Chi-squared test and test of equality of proportions. Pearson correlation test was used to measure the presence of an association between the percentages of positivity in population and LaLiga cohort. Results: 137,420 RT-PCR and 20,376 IgG serology tests were performed in 7,112 professionals. Positive baseline serology was detected in 10.57% of PLY and 6.38% of STF. Among those who started the follow-up as not infected and before STF vaccination, 11.87% of PLY and 5.03% of STF became positive. Before summer 2020 the prevalence of infection was similar than the observed at national level. The percentage of positivity in the Spanish population was higher than in LaLiga cohort, but both series showed a similar decreasing trend.
Potential for Aedes aegypti Larval Control and Environmental Friendliness of the Compounds Containing 2-Methyl-3,4-dihydroquinazolin-4-one Heterocycle
Authors: Nguyen Hung Huy , Ngo Huy Gia , Nguyen Giang Thi Truc , Setzer William N. , Ping-Chung Kuo , Nguyen Cong Tien
Published: August 2022

2-Methylquinazolin-4(3H)-one was prepared by reaction of anthranilic acid, acetic anhydride and ammonium acetate. The reaction of 2-methylquinazolin-4(3H)-one with N-aryl-2-chloroacetamides in acetone in the presence of potassium carbonate gave nine N-aryl-2-(2-methyl-4-oxoquinazolin-3(4H)-yl)acetamide compounds. The structures of these compounds were elucidated on the basis of their IR, 1H-NMR, 13C-NMR and HR-MS spectral data. These synthesized compounds containing the 2-methyl-3,4-dihydroquinazolin-4-one moiety exhibited excellent activity against Aedes aegypti mosquito larvae with LC50 values in the range of 2.085-4.201 μg/mL after 72 h exposure. Interestingly, these compounds did not exhibit toxicity to the non-target organism Diplonychus rusticus. In silico molecular docking revealed acetylcholine binding protein (AChBP) and acetylcholinesterase (AChE) to be potential molecular targets. These data indicated the larvicidal potential and environmental friendliness of these N-aryl-2-(2-methyl-4-oxoquinazolin-3(4H)-yl)acetamide derivatives.