bluuebunny/crossref_metadata_2025 huggingface dataset:
Commercialisation of human embryos and stem cells
Authors: Balakrishnan Preetham , Balu N.
Published: April 2022

The Multinational Corporations involved in stem cell research are lined up in the race to obtain patents for stem cells and economically exploit the patent within the time span of Twenty Years. Though stem cells  have the ability to change the lives of many patients, the full potential of the stem cells is yet to be unveiled. Albeit the concerns stem cells have been used in  regenerative therapies, to treat  COVID-19, Parkinson diseases. Hence countries like U.S, EU, Japan, South Korea have made huge investments in Research on stem cells. However, the trepidation of  morality, human right concerns on using embryos for research in stem cell industry has been criticized by human right activists, Feminists, religious leaders. This article analyses whether ‘human dignity’ and  ‘Human rights’ concerns in stem cell research and commercialization can be conceded to establish ‘highest standards of health’ from a right based approach.
reasons why prospective students choose a university, the cost of education or the quality of lecturers?
Authors: Harahap Dedy Ansari , Shaikh Mohsin , Nugraha Yudha Dwi , Amanah Dita
Published: April 2022

To analyze the effect of education costs and the quality of lecturers on student decisions to choose universities. Methods: A descriptive research design study was used. This involved 388 students (148 male, 240 female) from ten faculties at Islamic private universities in the city of Bandung. A questionnaire that was validated by experts was created to evaluate students' decision to choose a university. Results: The results report that partially the quality of lecturers has a greater influence on student decisions to choose universities than the cost of education. Meanwhile, simultaneously the cost of education and the quality of lecturers have a significant effect on student decisions to choose universities. Conclusions: Based on the theoretical model developed, this study also succeeded in building a regression model. The results of hypothesis testing indicate that the theoretical model achieved is partially and simultaneously the cost of education and the quality of the lecturers affect the student's decision to choose a university
Stress traumatico e interventi di prevenzione per gli operatori delle professioni di aiuto e dei sistemi di soccorso in emergenza NUE 112 Lazio
Authors: De Angelis Livio , Dell'Aquila Lucrezia , Villani Elisa
Published: April 2022

Introduzione: Le professioni di aiuto: il contatto con la sofferenza altrui Tutti coloro che svolgono professioni d’aiuto, pur nella specificità di ciascun contesto, sono accomunati da un comune denominatore: il contatto continuo e prolungato con la sofferenza altrui. Tali professionisti, infatti, nello svolgimento della loro mansione, oltre alle competenze di natura tecnica, utilizzano anche e soprattutto abilità sociali e relazionali per soddisfare i bisogni di un’utenza che necessita urgentemente di aiuto. La caratteristica dell’urgenza crea le condizioni per cui una scelta sbagliata può diventare determinante per l’incolumità altrui. Gli operatori, in contesti emergenziali, si confrontano quotidianamente con il paradosso di “comportarsi come persone normali in situazioni anormali”. In tale scenario essi devono agire, rapidamente ed efficacemente, orientandosi al fare più che al sentire. Non è del tutto scontato che chi svolge un lavoro del genere sviluppi una forma di tolleranza alle emozioni generate da situazioni traumatiche. Il distanziamento emotivo è una risorsa di coping sicuramente funzionale per raggiungere l’obiettivo. Eppure tale distacco può diventare patologico quando l’operatore non è più in grado di entrare in contatto con le emozioni suscitate dall’evento traumatico, spinto dalla volontà non consapevole di voler aderire allo stereotipo dell’imperturbabilità. La conseguenza diretta di tale processo fa sì che si tendano a sovrastimare le proprie capacità, sperimentando un senso di inadeguatezza ancora maggiore quando per qualche ragione si perde il controllo.
Utilization of NDMI Method in Landsat 8 Satellite Imagery for Analysis of Multi-Hazard Susceptibility
Authors: Suyeda Fadhil D. , Setiawan Budhi
Published: April 2022

Liquefaction and landslide can occur during earthquakes caused by changes in soil saturation levels so that the soil loses strength due to loss of tension between grains. One of the determinations of soil moisture data using satellite imagery analysis is Landsat. Landsat has provided moderate, global, synoptic spatial resolution and repeated earth's soil surface coverage. This paper discusses the multi-hazard susceptibility using Landsat-8 satellite imagery with a combination of NDMI (Normalized Difference Moisture Index) ratio bands in Sunurraya Village and Simpang Saga Village, South OKU Regency, South Sumatra. The combination of NDMI bands determines the spread of soil saturation levels and differences in moisture in vegetation conditions. Other supporting data are soil's physical properties, including water content, density, hydrometer analysis, and Atterberg limits analysis. Overlay of NDMI data analysis and soil test analysis shows the level of liquidation insecurity in the research area on a regional and local scale
ORGANIZATIONAL AND TACTICAL ISSUES INVESTIGATIONS OF CRIMES UNDER ARTICLE 201.1 OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION
Authors: ЗАХАРОВА Валентина Олеговна , ГАНИЕВ Ибрагим Магаметович
Published: April 2022

В статье обосновывается необходимость производства ряда следственных действий при расследовании преступлений, предусмотренных ст. 201.1 УК РФ, через призму организационных и тактических рекомендаций. Также даются рекомендации по планированию расследования данного состава преступления.

The article substantiates the need for a number of investigative actions in the investigation of crimes under Article 201.1 of the Criminal Code of the Russian Federation through the prism of organizational and tactical recommendations. The authors give recommendations for planning the investigation of this crime.
The Effect of Entrepreneurial Characteristics on Entrepreneurial Competence and Entrepreneurial Competence on Business Performance of Micro and Small-Scale Coffee Shops in Bogor
Authors: Aulia Muhammad Reza , Saragi Cyprianus PH , Simbolon Ramses
Published: April 2022

This research aims to analyze the influence of entrepreneurial characteristics towards entrepreneurial competencies and entrepreneurial competencies towards the business performance of micro and small scale coffee shops in Bogor. In this research, entrepreneurial characteristics consist of individual and psychological characteristics; which individual characteristics were reflected by age, education, experience, cosmopolitan; psychological characteristics reflected by motivation and need of achievement; entrepreneurial competencies reflected by managerial skill, conceptual skill, social skill, decision making skill and time managerial skill; business performance reflected by profit and sales volume. This research used 60 data samples of coffee shops consisting of 30 unit micro scale and 30 unit small scale coffee shops that were collected through random sampling in Bogor from February 2018 until June 2018. The data were analyzed by SEM-PLS analysis with SMART PLS 3 software. The result showed that entrepreneurial competencies in small scale model were influenced by individual characteristics and psychological characteristics whereas entrepreneurial competencies in micro scale model were only influenced by individual characteristics. The business performance was influenced by entrepreneurial competencies both in micro scale model and small scale model.
From Villages to World Markets: Women and E-Commerce in East Sumba, East Nusa Tenggara
Authors: Noer Khaerul Umam
Published: April 2022

This paper focuses on the use of e-commerce by women weaving craftsmen, in Sumba, East Nusa Tenggara. In 2020, We Are Social noted that 56% of Indonesia's population are active internet users, including 29% of the population are active e-commerce users. The Indonesian Creative Economy Agency report states that 36% of e-commerce traders in Indonesia come from rural areas, especially in Java. Data shows that fashion and craft-based creative industries have a high contribution to the national economy, and for this reason, the government has taken several policies in fostering and developing the creative industry, one of which is by increasing the development of business groups that are under the creative industry, especially those based on fashion and regional crafts. Sumba is known as Pahikung weaving where most of the industrial craftsmen are women. Using the ethnographic method, by interviewing twelve women weaving craftsmen, this paper explains that the marketplace opens up opportunities for better weaving sales by cutting distribution channels so that their products can be directly accepted by consumers, and by promoting through social media, they cut indirect costs. However, there are three main obstacles faced: production costs, distribution, and access to financial services. With this mapping, it is hoped that it will encourage more accommodative policies towards women craftsmen in rural and remote areas in Indonesia.
Effect of Fellow Involvement and Experience on Patient Outcomes in Spine Surgery
Authors: Levy Hannah A. , Karamian Brian A. , Yalla Goutham R. , Narayanan Rajkishen , Vijayakumar Gayathri , Gilmore Griffin , Canseco Jose A. , Woods Barrett I. , Kurd Mark F. , Rihn Jeffrey A. , Hilibrand Alan S. , Kepler Christopher K. , Vaccaro Alexander R. , Schroeder Gregory D.
Published: April 2022

Introduction:

Investigations in spine surgery have demonstrated that trainee involvement correlates with increased surgical time, readmissions, and revision surgeries; however, the specific effects of spine fellow involvement remain unelucidated. This study aims to investigate the isolated effect of fellow involvement on surgical timing and patient-reported outcomes measures (PROMs) after spine surgery and evaluate how surgical outcomes differ by fellow experience.

Methods:

All patients aged 18 years or older who underwent primary or revision decompression or fusion for degenerative diseases and/or spinal deformity between 2017 and 2019 at a single academic institution were retrospectively identified. Patient demographics, surgical factors, intraoperative timing, transfusion status, length of stay (LOS), readmissions, revision rate, and preoperative and postoperative PROMs were recorded. Surgeries were divided based on spine fellow participation status and occurrence in the start or end of fellowship training. Univariate and multivariate analyses compared outcomes across fellow involvement and fellow experience groups.

Results:

A total of 1,108 patients were included. Age, preoperative diagnoses, number of fusion levels, and surgical approach differed markedly by fellow involvement. Fellow training experience groups differed by patient smoking status, preoperative diagnosis, and surgical approach. On univariate analysis, spine fellow involvement was associated with extended total theater time, induction start to cut time, cut to close time, and LOS. Increased spine fellow training was associated with reduced cut to close time and LOS. On regression, fellow involvement predicted cut to close extension while increased fellow training experience predicted reduction in cut to close time, both independent of surgical factors and assisting residents or physician assistants. Transfusions, readmissions, revision rate, and PROMs did not differ markedly by fellow involvement or experience.

Conclusion:

Spine fellow participation predicted extended procedural duration. However, the presence of a spine fellow did not affect long-term postoperative outcomes. Furthermore, increased fellow training experience predicted decreased procedural time, underscoring a learning effect.

Availability of Data and Material:

The data sets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

Level of Evidence:

Level 3
LOCAL GOVERNMENT MANAGEMENT IN HANDLING COVID-19 IN KARIMUN DISTRICT
Authors: Aprizal Aprizal , Indrayani Indrayani , Azwandi Azwandi , Rahman Abdurr , Pasaribu Sapta
Published: April 2022

Covid-19 is a viral outbreak that is sweeping the world, Covid-19 is a virus outbreak that is transmitted from one person to another. This virus is the biggest problem that even big countries have to face, the COVID-19 virus has paralyzed the world's economy with the outbreak of the virus, of course, being an obstacle to the process of providing goods and services on the domestic and international scene. In Indonesia, the increase in the number of positive COVID-19 patients is moving fast. So, the government enforces the PSBB regulations as a preventive measure, of course this is also done by the Regency and City governments, one of which is Karimun Regency. The Karimun Regency Government also plays an active role in issuing policies to reduce the spread of the Covid-19 virus, while this strategy must have been taken into account with existing conditions.
Association of menstrual and reproductive factors with thyroid cancer in Saudi female patients
Authors: Alharbi Muslet , Alqefari Abdulelah , Alhawday Yasser , Alghammas Ali , Hershan Almonther , Abdulmonem Waleed , Alsudais Manal
Published: April 2022

Introduction: Thyroid cancer ranks the second highest cause of cancer among women in Saudi Arabia. Several risk factors have been reported as determinants of the onset of thyroid cancer. However, an association of menstrual and reproductive factors with thyroid cancer has not been completely explored in Saudi female patients with thyroid carcinoma. Objective: This study was designed to investigate an association of menstrual and reproductive factors with thyroid cancer in Saudi female patients. Methods: This is a case control study performed in Qassim University affiliated hospitals. The 90 Saudi females with thyroid cancer and 178 normal human controls of the same age groups were included. All participants were requested to complete a questionnaire based on their menstrual and reproductive history. Results: The analysis showed no statistically significant association between variables of mean age of menarche, current status of menopause, pattern of menstrual cycles, mean duration of menstrual cycle, mean age at first pregnancy, mean number of pregnancies, mean number of deliveries, mean number of live births, family planning methods used (intrauterine devices, used injectable and used oral contraceptives) and thyroid cancer. Conclusions: This is the first comprehensive study, to the best for our knowledge, from Qassim region of Saudi Arabia that demonstrates that menstrual and reproductive factors, have no significant association with the onset of thyroid cancer in Saudi females.
A Rare Anatomical Variation of the Spinal Accessory: Case Report
Authors: Al-Shaharani Abdullah
Published: April 2022

Anatomical variation in the location of the spinal accessory nerve as it relates to the internal jugular vein has been reported in the literature and anatomy texts. Knowledge of the landmarks of the spinal accessory nerve and its relationship to the internal jugular vein is extremely helpful in its identification during neck surgery for precluding neurovascular complications. The nerve mostly passes laterally (anterior) or medially (posterior) to the internal jugular vein at the level of the medial aspect of the posterior belly of the digastric muscle. However, there is a rare anatomical and surgical variant. In our case report, we describe an unusual relationship of the spinal accessory nerve to the internal jugular vein. In our case study, the nerve pierces the internal jugular vein.
The proportion of the divisor by the multiple In the Holy Quran from Surat Al-Saffat to Al-Adiyat
Authors: Alsaedy Monifah
Published: April 2022

The Qur’an is miraculous, and its miracle has many aspects, including: the rhetorical miracle, which among its forms is the oath method, as the harmony of its pillars with each other is evidence and evidence of the greatness and consistency of the Qur’an. In addition to the problems that appeared about the oath, some called for an added, omitted appreciation, which is the name of God Almighty before the division of creatures to get out of this problem. So: Consider choosing one of the traits of the divider rather than others, which leads to the consistency of the systems in its best form. The significance of this research: It is to highlight the aspects of proportionality between the divisor with the multiple, whether the descriptions are united or different, and to reveal the reason for choosing one of the characteristics of the divider without others. The subject of the study in this research: mentioning the sayings of the scholars regarding the divide by it and highlighting the aspects of proportionality between them. The multiple divisions have been presented in it in twenty-one places, all of which are in the last quarter of the Qur’an The subject of the study in this research: mentioning the sayings of scholars regarding the divide by it and highlighting the aspects of proportionality between them. I have concluded from the research with a set of results, including: that the attention to mentioning the proportionality between the divisor, although it appeared late, but its roots are rooted since the era of the righteous ancestors, may God be pleased with them, and this shows: through their sayings in the interpretation of what is meant by the sworn, And taking into account that relationship, and one of the recommendations of the research: Draw the attention of researchers to the fact that the method of oath in the Noble Qur’an still contains a remnant of who willing.
A Review of Awareness of Waste Recycling based on Web Application
Authors:   Computer Science & Engineering & Govindrao Wanjari College of Engineering & Technology, Nagpur, Nikhare Prachi Hirachand
Published: April 2022

Recycling is as of now a critical work for all nations. Among the turn out required for Recycling, trash arrangement is the most crucial stage to empower cost-proficient Recycling. In this paper, we endeavor to recognize single trash object in pictures and order it into one of the Recycling classes. We concentrate on a few methodologies also, give extensive assessment. Key Words: Recycling waste, Garbage classification.
Emotion Based Song Recommendation System
Authors:   Anjuman College of Engineering and Technology,, Shrivastav Prof. Ritesh
Published: April 2022

The mood or attitude of the user can be determined by the shape of his face. These expressions can be extracted from the live camera feed of the system. In the field of computer vision and machine learning (ML), where machines are trained to recognize different human emotions or feelings, much research is being done. The human emotions can be perceived through the various techniques provided by machine learning. One such strategy is to integrate the CNN and Keras model, which produces a less trained model and simplifies ML integration. Music is often used to control emotions, especially to change bad moods, to improve energy, or to reduce tension. In addition, listening to the right music at the right time can contribute to good mental health. Keyword- Face recognition, Image Processing, Computer Vision, Emotion Detection, Music, Mood detection.
UJI AKTIVITAS DAUN MAREME (Glochidion Borneense (Müll Arg) Boerl) SEBAGAI ANTIDIARE PADA MENCIT JANTAN GALUR SWISS WEBSTER
Authors: Anggraeni Reza , Alfiar Ilham , Suhendi Hendy
Published: April 2022

Diare  merupakan gangguan air besar (BAB) pada tubuh dimana bisa ditandai dengan frekuensi buang air besar (BAB) lebih dari 3 kali sehari dengan konsistensi fesesnya yang berbentuk cair. Pemanfaatan daun mareme secara empiris sebagai antidiare telah dilakukan oleh masyarakat sekitar daerah Banjarsari. Penggunaan daun mareme menggunakan jumlah helaian daun yang berjumlah ganjil. Tujuannya untuk mengetahui aktivitas dari daun mareme dan pada dosis berapakah yang memberikan aktivitas sebagai antidiare. Metode yang digunakan adalah induksi Oleum ricini pada mencit jantan Galur Swiss Webster. Esktrak etanol daun mareme diberikan sebanyak 0,39 mg /20 gram BB mencit, 0,78 mg /20 gram BB mencit, dan 1,56 gram /20 gram BB mencit. Sebagai pembanding digunakan loperamid HCL sebanyak 5,2 mg. Hasil aktivitas antidiare daun mareme pada parameter frekuensi feses menunjukan perbedaan yang signifikan (p<0,05) pada dosis 0,39 mg /20 gram BB mencit dan dosis 1,56 mg /20 gram BB mencit. Parameter konsistensi feses, bobot feses dan waktu muncul feses terdapat perbedaan yang signifikan (p<0,05) untuk dosis 0,39 mg /20 gram BB mencit, dosis 0,78 mg /20 gram BB mencit dan dosis 1,56 mg /20 gram BB mencit. Dosis yang memberikan aktivitas antidiare yang paling baik yaitu kelompok dosis 0,39 mg/20 gram BB mencit.
ANALISIS EFEKTIVITAS TERAPI DAN EFEKTIVITAS BIAYA TERAPI	ANTIBIOTIK PASIEN RAWAT INAP GASTRITIS DENGAN PENDEKATAN COST EFFECTIVE ANALISIS DI PUSKESMAS X
Authors: Fadiah Sugri , Sari Liska Marlinda
Published: April 2022

Gastritis menjadi salah satu gangguan pencernaan yang dialami masyarakat karena pola makan yang tidak sesuai atau dengan makanan yang terlalu pedas, sehingga produksi asam lambung tidak terkontrol. Cost Effectiveness Analysis (CEA) adalah tipe analisis yang membandingkan biaya suatu intervensi dengan beberapa ukuran non-moneter, dimana pengaruhnya terhadap hasil perawatan kesehatan. Penelitian ini untuk menghitung perbandingan effektivitas hasil terapi dan effektivitas biaya terapi antibiotik pasien gastritis rawat inap di PUSKESMAS dengan menggunakan perhitungan Average Cost-Effectiveness ratio (ACER) berdasarkan Cost Effectiveness Analysis, menggunakan metode purposive sampling, sehingga dapat diketahui terapi antibiotik yang paling Cost-Effective. Jadi kesimpulan dari penelitian ini nilai ACER dari Amoxicillin yaitu Rp.147.696, nilai ACER dari Cotrimoxazole yaitu Rp.287.261, nilai ACER dari Ceftriaxone Rp.366.628. Nilai ICER hasil dari perbandingan antara Antibiotik Ceftriaxone dengan Antibiotik Amoxicillin yaitu Rp.-1.807, dan antibiotik yang paling cost-efective adalah yang memiliki nilai ACER yang paling rendah yaitu antibiotik amoxicillin.
GAMBARAN POTENSIAL INTERAKSI OBAT PADA PASIEN DIABETES MILLITUS DIRAWAT INAP RSUD LINGGAJATI
Authors: Marsela Anis , Wisnu Wardaya Ahmad Wildan
Published: April 2022

ABSTRAK Diabetes mellitus merupakan sekumpulan penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau kedua-duanya, pengobatannya pun sering memerlukan waktu yang lama dan sering merupakan pengobatan lebih dari satu obat. Interaksi obat merupakan perubahan aktivitas farmakologi suatu obat karena pemakaian bersamaan dengan obat lain dan agen kimia lain. Penelitian ini bertujuan untuk mengetahui jumlah kejadian interaksi obat, gambaran interaksi obat berdasarkan tingkat keparahan, serta gambaran jenis dan jumlah kejadian interaksi obat diabetes mellitus pada pengobatan pasien diabetes mellitus di instalasi rawat inap RSUD Linggajati pada bulan Juli-Agustus 2021. Data yang diperoleh adalah lembar resep pasien diabetes mellitus, jenis penelitian ini adalah observasional dengan metode bersifat deskriptif menggunakan studi retrospektif, evaluasi penggunaan obat berdasarkan kajian interaksi obat secara teoritis berdasarkan aplikasi Medscape yang disajikan dalam bentuk tabel.
Analysis of Online Learning and Student's Level of Understanding in Islamic Education Subjects
Authors: Imam Tabroni  , Diaz Budiarti  , Rini Purnama Sari
Published: April 2022

Online learning has the potential to make students unable to understand the material presented by the teacher. This study aims to see the relationship between online learning and students' understanding of Islamic education subjects. The method used is correlation using a quantitative approach. The number of samples is the same as the total population, which is 28. After testing the instrument and collecting data, followed by data analysis using product moment correlation, the results of the research are that there is a positive relationship between online learning and students' understanding of Islamic education subjects. The positive relationship between online learning and students' understanding of this subject is 0.386. This relationship is good even though there are other factors that affect students' understanding of this online learning process.
Sebuah Analisis Perilaku Impulsif Karyawan
Authors: Hidayatulloh Panji , Arifianto Chandra
Published: April 2022

The purpose of this study was to analyze the impulsive behavior of employees in response to company policies. This research was conducted using a qualitative approach as a research procedure that produces descriptive data in the form of written or spoken words from 8 informants, namely employees of PT. Adhimix Precast Indonesia plant BSD 1, South Tangerang. The interactive model used in this study includes data collection, data reduction, data exposure, and drawing conclusions. The results obtained indicate that impulsive behavior that occurs can be in the form of acceptance or rejection of employees against policies issued by the company when they find policies that are felt to affect them, where the impulsive behavior that occurs is still at a safe level.
Implikasi Program Pelatihan Berbasis Ekonomi Kemasyarakatan Di Desa Bajo Kabupaten Boalemo
Authors: Fibriyanti S. Lakoro  , Sukrianto
Published: April 2022

The purpose of the study was to determine the type of program that is good in improving the community economy, especially economic-based development in Bajo Village. To find out the impact of a training program that does not go well. Finally, to find out the impact of the community-based economic training program in Bajo Village. The research method described in this study is a qualitative approach. The data analysis technique used using the Miles and Huberman model is data reduction, data presentation, and drawing conclusions. The results of the study can be explained that the implications of the Community Economic-Based Training Program in Bajo Village, Boalemo Regency are considered to be still not good due to the lack of capital needed by the community in business groups or individuals. In addition, the level of public awareness in carrying out the training program is considered not going well. Many things, like most people, are more focused on searching the sea or fishing. In addition, the community does not have the understanding and knowledge in carrying out entrepreneurship-based activities. Many people think that the results of managed products are only profitable for the community itself. Even the lack of marketing in running the business that is run.
Ellagic Acid and Hesperetin Ameliorates Lipopolysaccharide-Induced Multiple Organ Perturbation of Glycolytic and Mitochondrial Metabolizing Enzymes in Murine Model
Authors:   Department of Environmental Health Science, Faculty of Basic Medical Science, Ajayi Crowther University, Oyo,   Department of Chemical Sciences, Faculty of Natural Science, Ajayi Crowther University, Oyo,   Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Osun State University, Osogbo, Nigeria
Published: April 2022

Lipopolysaccharide is an endotoxin derived from gram-negative bacteria and its pathophysiology has been linked to septicemia and fatty liver among other multiple organ toxicity. This study was designed to investigate the ameliorative effect of Hesperetin and Ellagic acid against LPS-induced perturbation on glycolytic and mitochondrial metabolizing enzymes. Eighteen Balb/c albino mice were assigned into three groups of six mice each: Group A (control) received olive oil and DMSO orally for 28 days, group B received LPS (250 µg/kg/BW) intraperitoneally for 14 days. Group C were pre-treated with Hesperetin (40 mg/kg/BW) and Ellagic acid (30 mg/kg/BW) orally for 14 days prior to co-administration of LPS (250 µg/kg/BW) for another 14 days. The mice were sacrificed, blood was collected into heparinized tubes while liver, kidney, and spleen were excised. Glycolytic enzyme and mitochondrial metabolizing enzymes activity were assayed in the kidney, liver, spleen, plasma, erythrocytes, and lymphocytes. Results are expressed as mean ± SEM. The level of homogeneity among the groups was assessed using analysis of variance (ANOVA). There was a significant (P<0.05) down-regulated activities of hexokinase, aldolase, lactate dehydrogenase, and NADase when compared with control. Also, activities of mitochondrial metabolizing enzymes (succinate dehydrogenase, malate dehydrogenase, combined complexes I+III, II+III, and IV) were all significantly (P<0.05) deceased relative to control. Ellagic acid and hesperetin ameliorated glyco-metabolic perturbations induced by exposure to lipopolysaccharide which has been correlated with risk factors for various metabolic disorders. Data from this study indicates that the use of ellagic acid and hesperetin ameliorate glyco-metabolic toxicity associated with Lipopolysaccharides.
The 30 October 2020, Mw 6.6 Sisam (Samos) Earthquake: Interpretation of Strong Ground Motions and Post-Earthquake Condition of Nearby Structures
Authors: AKANSEL Vesile Hatun , ÖZKULA Gülen
Published: April 2022

A major magnitude Mw 6.6 earthquake struck offshore of the city of İzmir, Turkey and the city of Neon Karlovasion, Greece which has the epicenter located at north of Sisam/ Samos Island in the eastern Agean Sea on October 30th, 2020. The moment magnitude of the earthquake has been reported variously, such as 6.6, 6.9 and 7.0 by different agencies. Seismic instruments indicate the earthquake originated at a depth of 17.2 and 21 kilometers according to the Disaster and Emergency Management Presidency (AFAD) of Turkey and USGS. Doğanbey Payamlı, Ürkmez, Gümüldür, Kavakdere are the closest coastal villages of İzmir to the epicenter. The earthquake affected the mid-rise buildings located on the soft soil and then, tsunami stroked the coastal villages of İzmir. In this study, the strong ground motion records in a distance range from epicenter to 150 km are analyzed to investigate the characteristic of the ground motions. The post-earthquake field observations mainly for the mid-rise reinforced concrete structures are reported. The spatial distribution of the damage indicates a basin effect within the Bayraklı, Bornova and Karşıkaya regions. The 8-10 story mid-rise buildings affected from the main and aftershocks and the north coasts of İzmir affected from the tsunami were the main observations of this earthquake.
Envisioning Future Scenarios: Teaching and Assessing Values-based Design Approaches
Authors: Eriksson Eva , Hansen Anne-Marie , Nilsson Elisabet M.
Published: April 2022

This article addresses the need for teaching materials and systematized methods for teaching and assessing values-based design approaches. We do so by suggesting the teaching activity Envisioning future scenarios,which is based on utopian and dystopian scenarios in line with values-based design approaches such as speculative and critical design and related to design fiction practices. The teaching activity is presented with learning outcomes, instructions for how to implement it, corresponding assessment activities and criteria, and illustrated by a teaching case description. The article ends with a discussion on how the learning outcomes, the teaching activity, and the assessment are brought together in line with the principles of constructive alignment. Through this, we argue that the shortcoming of teaching materials and systematized methods for teaching and assessing values-based design approaches, such as speculative and critical design, can be addressed by aligning intended learning outcomes with teaching and assessment activities, and by applying a general structural framework such as e.g. the SOLO taxonomy, for defining and evaluating learning outcomes. The suggested teaching and assessment activities can be applied in educational domains as diverse as product and service design, engineering, architecture, media and communication, human-computer interaction, socio-technical studies and other creative fields.
Be provoking. Schooling critical and speculative designers
Authors: Pérez-Orrego Natalia , Arango-Flórez John , Fernandez-Silva Claudia , Mira-Duque Juan David
Published: April 2022

Designing the provocation is a powerful strategy to jump from denouncing to generating actions and behaviors of a critical and speculative nature in design students. This article presents the discursive character of critical design function through three guidelines for provocation design: intellectual risk, generative challenge, and embodied futures, based on the philosophical concept of experience as an act of knowledge. Those are discussed on three classroom experiences in clothing design, architecture, and industrial design in Medellín, Colombia, showing possibilities and challenges for critical and speculative design schooling as well as bringing teachers and students closer to new ways of interacting with social problems in the context of Latin America.
Insights for Educational Practice from a Thematic Analysis of Student Experiences with Speculative Design Mini-Projects about Personal Issues
Authors: Kender Kay , Purgathofer Peter
Published: April 2022

In 2020, we gave a large-scale first-year informatics course an assignment to speculatively design hypothetical solutions for issues they were experiencing due to social distancing measures during the COVID-19 pandemic. In this paper, we present a speculative design mini-project, then analyse student feedback and present insights about applying speculative design mini-projects around personal issues and in a large-scale technology education context. Our findings indicate that students had strong emotional experiences throughout the process and gained deeper insights into both design and the issues they were engaging with. Through peer reviews, students found new perspectives and feelings of relatedness in the face of shared hardships. From this, we summarise learnings for teaching practice about 1) peer review as a tool for feedback loops and discussions, 2) safety and student well-being when addressing personally experienced issues, 3) abridged design processes for trans-disciplinary competency, and 4) fostering safe spaces for creative vulnerability.
An Analysis of Synchronous and Asynchronous Online Undergraduate Learning During the COVID Pandemic
Authors: Al-Areibi Iman , Dickson Brandon , Kotsopoulos Donna
Published: April 2022

In response to the COVID pandemic, university classes across the world were forced online. In this research, we explored students’ experiences in emergency online learning in two undergraduate business classes. Where the literature on online learning has traditionally focused on those students who chose online learning, in light of recent shifts in education, online learning continues to increase its prevalent in the education of all students, even those who would not have traditionally chosen this medium. In this research, through the use of learning platform metadata and students survey responses, we examined the impact of the various pedagogical techniques used in the online classroom and their ability to maintain high student motivation. Ultimately, we concluded that providing multiple opportunities for engagement through the use of both synchronous and asynchronous tools in is crucial to promoting student motivation, learning and course success. Implications for classroom instruction and further research will be discussed.
MODELS OF WORLD CAPITALS IN THE PROSE OF THE XXI CENTURY
Authors:   Eurasian Humanitarian Institute, Kazakhstan, Amangazykyzy Moldir , Sayfulina Flera ,   Kazan Federal University, Kazan, Russian Federation
Published: April 2022

The paper dwells on the topical problem of modern literary criticism – the study of the creation of a literary image – a model of the capitals of the world in prose of the 21st century. The article also engages the following socially important issues, such as city life, a little man the city, the problem of loneliness, aloofness of an individual.The work is directly connected with the actualization of urban theme in literature at the beginning of the third millennium. The article begins with a review of the theoretical literature on matters under investigation. The methodological basis of the research is the works by the scholars, such as M. Beville, A. Wessels, P.Torkamane, S.V. Pirogov, V. V. Tsurkan, T.I.Vasilieva, N.L. Karpicheva and others. The following postmodern novels are the object of research – Just Together (2004) by French writer Anna Gavalda, The Book Without Photos (2011) by Russian prose writer Sergei Shargunov, White Orda (Ақ Орда) (2005) by Kazakh author Dukenbay Doszhan. Using hermeneutic analysis of the selected literary works which depict the world capitals such as Paris, Moscow and Nur-Sultan, we have identified the following models of the capital: 1. «Capital – a chronotope»; 2. «Capital – a beautiful city»; 3. «Capital is a city of memories»; 4. «Capital is an Orthodox city»; 5. «Capital is a city of career»; 6. «Capital is a symbol of a new country».
LANGUAGE CONTACTS IN KAZAKHSTAN: THE LANGUAGE OF MULTILINGUAL YOUTH
Authors:   Nazarbayev University, Kazakhstan, Baiteliyeva Zhanar
Published: April 2022

This article examines the condition of language contacts in Kazakhstan. In particular, the issue of language contacts in higher educational institutions, where the main disciplines related to the majors in the country are taught in English. Now the number of such educational institutions is growing. In order to predict the occurrence of language contacts in these institutions, the degree of their influence on each other in the future, first of all, a study and analysis of students’ conversations in real situations were carried out. Research questions are: What languages do students want to use in different situations, and how do different situations affect their language choices? How and in what direction does the use of languages change during a conversation? The main goal of the study is to determine the functions of the Kazakh, Russian and English languages, which are currently widely used in Kazakhstan. Moreover, the study aims to find out how (how often) and where Kazakhs who graduated from Kazakh schools can use these languages. By responding to these questions, the author analyzes the reasons why young people use different languages in different situations.
THE DIDACTIC ESSENCE OF TURKIC PEOPLES’ POETRY
Authors:   Astana International University, Omarova Saule
Published: April 2022

The article considers didactic motives in the works of the great thinkers of Turkic folk literature N.Ganzhaui, A. Navoi, A. Kunanbayuly. The problems of teaching poets, comprehensive education and development of intelligence, instilling moral qualities are compared and analyzed. There are edifying Gazelles, philosophical thoughts aimed at educating the younger generation with such moral qualities as diligence, humanism, patriotism, kindness, truthfulness, justice, honesty. Attention is drawn to the fact that in works representing scientific, philosophical, moral, religious ideas related to the didactic genre, and sermons, edification, a bundle, opinion, conclusion, commandment, sermon, propaganda, and not an artistic image and image prevail. Azirbayzhan, Uzbek People's statesman, the outstanding thinker N.Ganzhaui and A. Nauai are the pinnacle of Kazakh poetry, they say that the brilliant poet Abai Kunanbayev recognized himself as a teacher and received spiritual nourishment from their pearls.In Kazakh literature, it is proved by examples that "Karasozderi" and Abai's poems are traditional continuations of oriental didactic works.
SISTEMA DE IÇAMENTO DE CARGAS PARA HELICÓPTEROS DE RESGATE
Authors: Cuchi Rafael , Zappelino Bruna De Freitas , Ballmann Thais De Jesus , Da Silva Vanderlei , Prestini Dani , Ferreira Herlon Martins , Azevedo George Luis
Published: April 2022

Aeronaves de resgate são usadas para agilizar a evacuação e fornecer suporte avançado às vítimas. Comparados com o resgate em barco ou terrestre, os helicópteros fornecem acesso rápido e visualização aérea durante a busca. Nesse sentido, este estudo tem por objetivo contribuir com o trabalho da polícia militar em situações de resgate, aumentando a capacidade de carga durante o içamento de vítimas e propiciando segurança durante a operação. Para tanto, com o auxílio das metodologias PDP (Processo de Desenvolvimento de Produto), foi desenvolvido um dispositivo para içamento de carga, com capacidade de 4000 N, devidamente dimensionado e de fácil manuseio. O procedimento experimental seguiu tendo como balizador as metodologias PDP atreladas ao sistema CAx. Utilizando a junção dessas ferramentas, foi possível elaborar uma solução que permitiu o içamento de vítimas pelo lado externo do helicóptero e garantiu a segurança dos profissionais envolvidos durante a operação.
Cultural Systems in Water Management for Disaster Risk Reduction: The Case of the Ladakh Region
Authors: Kandari Sweta , Pasupuleti Ram Sateesh , Samaddar Subhajyoti
Published: April 2022

Abstract There has been an increase in hydrological disasters over the past few decades as a result of climate change. Also, there is a growing recognition of the need to integrate traditional knowledge into Disaster Risk Reduction (DRR) and Climate Change Adaptation (CCA) policies and practices on a global scale. Traditionally, village folk have used observation-based, traditional methods to avoid high economic costs associated with sustainable management of their resources and livelihood. Due to ongoing climate change impacts and migrations, indigenous knowledge is gradually disappearing, and other modern systems have been unable to effectively replace it to the desirable extent. This paper investigates how the traditional knowledge and cultural systems of local communities living in the high-altitude cold desert region of the Ladakh region in India have contributed to their water management systems. In addition, the article discusses how haphazard changes in the contemporary environment are causing issues related to water scarcity and livelihood leading to the slow onset of disasters. Through non-participant observations during a two-month volunteering engagement and literature review, the present study attempts to track the changing realm and attitude of the Ladakhi community towards water conservation in light of climate change and depleting resources. A comparison was made between the government and non-government initiatives for the conservation and management of water resources. The results of this study suggest that traditional knowledge and cultural systems have a significant role in increasing community participation and awareness of climate change and disaster risk.
Design and evaluation of a prototype of a children’s educational application during and for the COVID-19 pandemic and beyond
Authors: Monteiro Ingrid T. , Lourenço Edney L. de Q. , Brilhante Marcelo Q. de L. , De Freitas Adriano T. , Oliveira Francisco C. de M. B. , De Castro Francisco E. B. , De Oliveira Ana C. B.
Published: April 2022

Covid-19 pandemic affected virtually every sector of life, due to the need to avoid agglomerations and maintaining social isolation. In education, teaching-learning processes have changed drastically and now are in a state of fast transformation. Schools all around the world were closed and teachers and students had to migrate to online environments. In this paper, we present a whole design process of conceiving an educational mobile application that explores the students' houses as a source of knowledge through gamification and augmented reality. Field studies such as online surveys and user diaries were employed and resulted into the creation of eleven personas representing teachers, parents, and students. After a brainstorming session and the definition of the basic requirements, a low-fidelity prototype was created and evaluated by ten students aged 6 to 11 years old from both public and private schools. The results of the evaluation pointed to the potential of the app in keeping children motivated and interested in learning while at home. We highlight the challenges and lessons learned in doing user research involving kids during a pandemic.
Improving the Security of ChaCha against Differential-Linear Cryptanalysis
Authors: Coutinho Murilo , Passos Iago , Sousa Jr. Rafael T. de , Borges Fábio
Published: April 2022

The stream cipher ChaCha has received a lot of attention and recently is being used as a new cipher suite in TLS 1.3, as a random number generator for operating systems (Linux, FreeBSD, OpenBSD, NetBSD, and DragonFly BSD), a proposed standardization in RFC 7634 for use IKE and IPsec, and by the WireGuard VPN protocol. Because of that, it is very important to understand and study the security of this algorithm. Previous works showed that it is possible to break up to 7 of the 20 rounds of ChaCha. In this paper, we show that a simple modification in the algorithm, namely changing the rotation distances in the Quarter Round Function, makes ChaCha more secure against all the most effective known attacks without any loss in performance. In fact, we show that with these changes, it is only possible to break up to 6 rounds of ChaCha. Therefore, it would be no longer possible to break 7 rounds of ChaCha with the best-known attacks.
LGPD: Levantamento de Técnicas Criptográficas e de Anonimização para Proteção de Bases de Dados
Authors: Sousa Thiago R. , Coutinho Murilo , Coutinho Lilian , Albuquerque Robson
Published: April 2022

A Lei nº 13.709, de 14 de agosto de 2018, conhecida como Lei Geral de Proteção de Dados Pessoais (LGPD), veio para instituir princípios e regras para a proteção das pessoas naturais no que diz respeito ao tratamento de seus dados, principalmente no formato digital. Por essa razão, surge a necessidade de se estabelecer soluções tecnológicas capazes de atender às imposições da lei. Neste trabalho, apresentamos um levantamento de técnicas e ferramentas de anonimização e de criptografia que demonstram potencial para auxiliar no cumprimento da LGPD, no caso específico da proteção de bases de dados. Dentre as técnicas comparadas, percebe-se que não há nenhuma que atenda perfeitamente a todas as situações, seja por questões de desempenho ou por considerações de segurança. Ainda assim, conclui-se que, quando possível, essas soluções devem ser utilizadas, pois têm o potencial de aumentar significativamente a segurança dos sistemas e auxiliar no cumprimento da lei.