bluuebunny/crossref_metadata_2025 huggingface dataset:
Reduction of work accidents through the implementation of containers for solid waste collection
Authors: Dos Santos Nailson Diniz , Zlatar Tomi , Da Cruz Felipe Mendes , Barkokébas Junior Béda , Lago Eliane Maria Gorga
Published: April 2020

The activity of waste collection is fundamental for preserving human health and the environment. As the world population increases, so does the waste production, consequently leading to a higher number of professionals involved in the collection activity. The objective of this study was to identify the main causes of accidents in urban waste collection and to verify if the implementation of containers would reduce the number of accidents in the sector. The causes were identified by analyzing accidents in two waste-collection companies for 4 years. Company A had 3,859 employees with 756 registered accident cases, while company B had 2020 workers with 189 cases. In total, it was analyzed 945 accident cases from urban waste collection. One municipality from company A which implemented the highest number of containers was studied thoroughly to verify if the implementation of containers reduces the number of accidents. The analysis shows that the household collection had the highest accident rate, with 65.61%. Sharp materials and falls were the leading causes of accidents, representing 53% in the company A and 62% in the company B. After containers implementation, the number of accidents caused by sharp materials and falls decreased from 37 without the container in 2014, to 18 with the container in 2015, and 11 with the container in 2016. It was concluded that the implementation of containers improves occupational safety and health during the urban cleaning process. Further studies should be conducted in order to improve the working conditions in the urban cleaning sector.
Application of bodybuilding for correction of musculoskeletal disease in Patellofemoral Pain Syndrome - A case report
Authors: Pereira Pablo Monteiro , Reis João , Duarte J. , Santos Baptista J. , Torres Costa J. , Conceição Filipe
Published: April 2020

Background: Medicine and Physical Education can work together to solve many health problems. Bodybuilding is a multidisciplinary area whose goals can range from body development to the correction of postural problems and the resolution of various pathologies related to human movement. In the case in analysis, the patient presented (at rest) localized pain (twinges) in the anterior face of the left knee, with an intensity of five (0-10 scale), without phlogistic signs, which worsens when performing the squat, hindering him from leaving the bed without pain. Symptoms were exacerbated when descending stairs. Through anamnesis and directed physical examination, it were considered the possible differential diagnosis of pain in the anterior portion of the knee: Diseases in menisci,  anterior and posterior cruciate ligament injuries,  diseases of  knee  collateral  ligaments,  diseases of  knee  cartilage,  diseases of  patellar tendon tendinitis and patellar chondromalacia. After a correct diagnosis of patellofemoral pain  syndrome, a conservative treatment was performed using bodybuilding. The results were positive after four months of treatment. From this case, it can be concluded that bodybuilding can be an alternative solution for the conservative treatment of Patellofemoral Pain Syndrome
Self-mutilation and suicide in the military: a systematic review protocol
Authors: Ribeiro Marcelo Montebello , Fernandes M. M. , Trajano T. F. B. X. , Costa E. A. M. M.
Published: April 2020

As one of the three leading causes of death in people between the ages of 15 and 44 years old, suicide is, according to data from WHO, responsible annually for a million deaths. These numbers do not include suicide attempts, that are usually 10 to 20 times more frequent than suicide itself. This systematic review proposes to gather relevant information on the topic of self-harm and suicide in the Army, following the PRISMA-P statement for systematic review and meta-analysis protocols. This systematic review protocol was developed to present suitable guidelines for the development of research that can provide results to fulfil the sought objective. The search will cover the dates between 2014 and May 2019. Five databases will be accessed (SCOPUS, PubMed, Science Direct, EBSCOhost and Web of Science) with a total of six keyword combinations. The Cochrane Collaboration Tool will assess study selection and quality for determining the risk of bias.
In Situ Visualizing the Recognition Between Proteins and Platinum-Damaged DNA in Single-Cells by Correlated Optical and Secondary Ion Mass Spectrometric Imaging
Authors: Lin Yu , Wu Kui , Jia Feifei , Chen Ling , Wang Zhaoying , Zhang Yanyan , Luo Qun , Liu Suyan , Qi Luyu , Li Nan , Fang Xiaohong , Dong Pu , Gao Fei , Zhao Yao , Wang Fuyi
Published: April 2020

In situ visualization of the recognition and interaction between proteins and drug damaged DNA at single cell level is highly important for understanding the molecular mechanism of action of DNA targeting drugs, yet a great challenge. We herein report a novel approach, termed as correlated optical and secondary ion mass spectrometric imaging (COSIMSi), for exploring the recognition between proteins and cisplatin-damaged DNA in single cells. Genetically encoded EYFP-fused HMGB1, an in vitro well-known specific binder of cisplatin-damaged DNA, and dye-stained DNA, and cisplatin were mapped by LSCM and ToF-SIMS imaging, respectively. The LSCM and SIMS images were aligned with aiding of an addressable silicon wafer to generate fused images, in which the co-localization of the fluorescence and MS signals indicated the formation of HMGB1-Pt-DNA ternary complexes in a dose- and time-dependent manner. In contrast, COSIMSi showed that little HMGB1(F37A)-Pt-DNA complex was produced under the same conditions. Moreover, we demonstrated for the first time that cisplatin lesion on DNA prevented a DNA-binding protein Smad3 from interacting with DNA. These results verify that the COSIMSi is an effective and straightforward tool for in situ visualization of recognition and interaction between proteins and specific damaged DNA in single cells.
Ion-Mobility Mass Spectrometry of Glycans and Glycopeptides Using Both Intact and Glycan Sequencing Approaches In Positive Ion Mode Facilitates Glycan Isomer and Glycan Motif Identification
Authors: Pallister Edward , Choo Matthew , walsh ian , tai jien nee , Tay Shi-Jie , Yang Yuansheng , Ng Say-Kong , Rudd Pauline , Flitsch Sabine , Nguyen-Khuong Terry
Published: April 2020

High resolution glycan analysis has become an important part of biopharmaceutical API production and quality control. Liquid chromatography (LC) is now a well-established technique in this field but the resolution of similar isomeric glycan structures is still a challenge. Here we show that the addition of ion mobility spectroscopy (IMS) in a hyphenated LC-IMS-MS setting allows for the high resolution of N-glycan isomers during positive ion analysis. We have identified unique features in the IM chromatograms to help differentiate a range of isomeric N-glycans for both RFMS labelled glycans and glycopeptides.
Visualizing Semipermeability of Cell Membrane by a pH-responsive Ratiometric AIEgen
Authors: Gu Yuan , zhao zheng , Niu Guangle , Zhang Han , Wang Yiming , Tsz Kin Kwok Ryan , Lam Jacky W. Y. , Tang Ben Zhong
Published: April 2020

In clinical chemotherapy, some basic drugs cannot enter the hydrophobic cell membrane because of ionization in acidic tumor microenvironment, a phenomenon known as ion trapping. In this study, we developed a method to visualize this ion trapping phenomenon by utilizing a pH-responsive ratiometric AIEgen, dihydro berberine (dhBBR). By observing the intracellular fluorescence of dhBBR, we found that non-ionized dhBBR can enter cells easier than ionized forms, which is in accordance with the concept of ion trapping. In addition, dhBBR shows superior anti-photobleaching ability than Curcumin thanks to its AIE property. These results suggest that dhBBR can serve as a bioprobe for ion trapping.
Enantioselective Partitioning of Polychlorinated Biphenyls in a HepG2 Cell Culture System: Experimental and Modeling Results
Authors: Zhang Chun-Yun , Flor Susanne , Ludewig Gabriele , Lehmler Hans-Joachim
Published: April 2020

We investigated the partitioning of chiral PCBs (PCB 91, PCB 95, PCB 132, or PCB 136) in the human hepatoma HepG2 cell line and used a computational model for the in vitro to in vivo extrapolation (IVIVE) of PCB levels. HepG2 cells were incubated with PCBs for 72 h. PCB levels were quantified in cells, media, and cell culture dishes. PCBs were present in cell culture medium > cells > dishes, and displayed atropisomeric enrichment in cells and dishes. The free PCB concentration in media, estimated using polyparameters linear free energy relationships (PP-LFERs) and a composition-based model, was used to extrapolate from the nominal PCB concentration used in vitro to PCB tissue levels and vice versa. This approach allows for an IVIVE but does not account for the atropselective partitioning of chiral PCBs between medium and cells.
Overcoming Back Electron Transfer Facilitates the Implementation of Electron Donor-Acceptor Complexes in Catalysis
Authors: McClain Edward , Monos Timothy , Mori Mayuko , Beatty Joel , Stephenson Corey
Published: April 2020

Electron donor-acceptor (EDA) complexes can controllably generate radicals under mild conditions through selective photoexcitation events. However, unproductive reactivity from fast deactivation of the photoexcited complexes through back electron transfer has slowed the development of EDA complexes in synthetic methodology. Here, we disclose the study of EDA complexes derived from 2-methoxynaphthalene donor and acylated ethyl isonicotinate N-oxide acceptor that undergo a fast N–O bond fragmentation event upon photoexcitation. This reaction design not only overcomes the limitations of back electron transfer but also enables the regeneration of the donor species, representing a rare example EDA photochemistry in a catalytic regime. The synthetic utility is demonstrated through visible light-driven radical trifluoromethylation and Minisci alkylation reactions. The scalability of the EDA complex promoted reaction evidenced by the successful multigram-scale trifluoromethylation of methyl N-Boc pyrrole-2-carboxylate in a continuous flow manifold.
3D Printing and Growth Induced Bending based on PET-RAFT Polymerization
Authors: Bainbridge Chris , Engel Kyle , Jin Jianyong
Published: April 2020

4D printing has steadily become an emerging area of advanced manufacturing research and has produced some truly fantastic innovations. Previously we have demonstrated the 3D printing process based on PET-RAFT polymerization, and its subsequent capability in the post-production modification of surface properties. In this work, (1) we further optimized the PET-RAFT 3D printing formulation by replacing RAFT agent CDTPA with BTPA and adjusting the monomers composition; (2) we also observed the photodegradation of the photocatalysts EB and EY under 405nm light and the effects this has on 3D printing; (3) we then did successful 3D printing using a commercial 405nm DLP 3D printer, with an improved build speed of up to 2286 µm/hr; (4) lastly, for the first time we have demonstrated a method for growth induced bending of a 3D printed strip, where the growth on one side of the strip causes stress and the strip bends accordingly to reach a more comfortable position.
Comparative Docking Analysis of Rational Drugs Against COVID-19 Main Protease
Authors: SAMANT LALIT , Javle Vyomesh
Published: April 2020

COVID-19, a new strain of coronavirus (CoV), was identified in Wuhan, China, in 2019. No specific therapies are available, and investigations regarding COVID-19 treatment are lacking. Crystallised COVID-19 main protease (Mpro), which is a potential drug target. The present study aimed to assess drugs found in literature as potential COVID-19 Mpro inhibitors, using a molecular docking study. Molecular docking was performed using Autodock 4.2, with the Lamarckian Genetic Algorithm, to analyse the probability of docking. The docking was cross-validated using Swiss Dock. COVID-19 Mpro was docked with several compounds, and docking was analysed by Biovia Discovery Studio 2020. Quinine and hydroxychloroquine were used as standards for comparison. The binding energies obtained from the docking of 6LU7, 2GTB with screened drugs viz., Quinine, Artesunate, Clotrimazol, Artemether, Quercetin, Mefloquine, ciprofloxacin, clindamycin, cipargamin, SJ-733 were in between -7.0 to -9.6 kcal/mol. On consideration of similar binding energy obtained from Autodock vina and SWISSDock and interaction residue pattern specifically (GLU 166,CYS 145, CYS44 and MET 49 residue) for SJ-733 & JPC-3210 may represent potential treatment options, and appeared to have the best potential to act as COVID-19 Mpro inhibitors. However, further research is necessary to investigate their potential medicinal use against CoV.
The Local Environment of Iron Determines the Rupture Force of Rubredoxin and Not Hydrogen Bond Networks
Authors: Scheurer Maximilian , Dreuw Andreas , Head-Gordon Martin , Stauch Tim
Published: April 2020

The surprisingly low rupture force and remarkable mechanical anisotropy of rubredoxin have been known for several years. Exploiting the first combination of steered molecular dynamics and the quantum chemical Judgement of Energy DIstribution (JEDI) analysis, the distribution of strain energy in the central part of rubredoxin is elucidated in real-time with unprecedented detail. In contrast to common belief that hydrogen bonds between neighboring amino acid backbones and the sulfur atoms of the central FeS4 unit in rubredoxin determine the low mechanical resistance of the protein, we demonstrate that structural anisotropy as well as the contribution of angle bendings in the FeS4 unit are instead the key factors responsible for the low rupture force in rubredoxin. In addition to clarifying the structural basis for the mechanical unfolding of an important metalloprotein, this study paves the way for in-depth investigations of an intriguing new class of mechanophores involving metal ions.
In Vitro-Evolved Peptides Mimic a Binding Motif of the G-Actin-Binding Protein Thymosin-B4 and Serve as Research Tools
Authors: Gübeli Raphael , Bertoldo Davide , Shimada Kenji , Gerhold Christian , Hurst Verena , Takahashi Yuichiro , Wilbs Jonas , Harata Masahiko , M. Gasser Susan , Heinis Christian
Published: April 2020

Actin is the most abundant protein in eukaryotic cells and is key to many cellular functions. Natural products that specifically recognize the filamentous form of actin (F-actin) such as the bicyclic peptide phalloidin are important tools to study actin and are widely applied for imaging the cytoskeleton in cells. Herein, we aimed at developing peptide-based affinity reagents that selectively bind to the monomeric form of actin (G-actin), for which synthetic probes are not available. Panning a phage display library comprising more than a trillion different bicyclic peptides against G-actin yielded binders with low nanomolar affinity and greater than 1000-fold selectivity over F-actin. Sequence analysis revealed a strong similarity of the peptides' sequences to a region of thymosin-b4, a protein that weakly binds G-actin, and competition binding experiments confirmed a common binding region at the cleft between the subdomains 1 and 3 of actin. We tested the G-actin peptides as probes in pull-down and imaging experiments and applied a peptide variant with improved dissociation constant (Kd = 5 ± 2 nM) to measure the affinity of G-actin-binding natural product toxins.
Anodic Oxidation of Dithiane Carboxylic Acids: A Rapid, Mild and Practical Way to Access Functionalised Orthoesters
Authors: Garcia Anthony , Leech Matthew , Petti Alessia , Denis Camille , Goodall Iain C. A. , Dobbs Adrian , Lam Kevin
Published: April 2020

A new electrochemical methodology has been developed for the preparation of a wide variety of functionalised orthoesters under mild and green conditions from easily accessible dithiane derivatives. The new methodology also offers an unprecedented way to access tri(fluorinated) orthoesters, a class of compound that has never been studied before. This provides the community with a rapid and general method to prepare libraries of functionalised orthoesters from simple and readily available starting materials.
Electronic Structure Benchmark Calculations of CO2 Fixing Elementary Chemical Steps in RuBisCO Using the Projector-Based Embedding Approach
Authors: Douglas-Gallardo Oscar A. , J. Shepherd Ian , Bennie Simon , Ranaghan Kara , Mulholland Adrian , Vöhringer-Martinez Esteban
Published: April 2020

Ribulose 1,5-bisphosphate carboxylase-oxygenase (RuBisCO) is the main enzyme involved in atmospheric carbon dioxide (CO2) fixation in the biosphere. This enzyme catalyses a set of five chemical steps that take place in the same active-site within magnesium (II) coordination sphere. Here, a set of electronic structure benchmark calculations have been carried out on a reaction path proposed by Gready et al. by means of the projector-based embedding approach. Activation and reaction energies for all main steps catalyzed by RuBisCO have been calculated at the MP2, SCS-MP2, CCSD and CCSD(T)/aug-cc-pVDZ and cc-pVDZ levels of theory.

The treatment of the magnesium cation with post-HF methods is explored to determine the nature of its involvement in the mechanism. With the high-level ab initio values as a reference, we tested the performance of a set of density functional theory (DFT) exchange-correlation (xc) functionals in reproducing the reaction energetics of RuBisCO carboxylase activity on a set of model fragments. Different DFT xc-functionals show large variation in activation and reaction energies. Activation and reaction energies computed at the B3LYP level are close to the reference SCS-MP2 results for carboxylation, hydration and protonation reactions.

However, for the carbon-carbon bond dissociation reaction, B3LYP and other functionals give results that differ significantly from the ab initio reference values. The results show the applicability of the projector-based embedding approach to metalloenzymes. This technique removes the uncertainty associated with the selection of different DFT xc-functionals and so can overcome some of inherent limitations of DFT calculations, complementing and potentially adding to modelling of enzyme reaction mechanisms with DFT methods.
A Dinuclear Copper Based Artificial Antibody for the Naked-Eye Detection of Glyphosate
Authors: Rossel Thibaud , Creus Marc
Published: April 2020

In the presence of bovine carbonic anhydrase(bCA) and human carbonic anhydrase (hCAII), [Cu2(HXTA-ArS)]- at physiological pH offered a synthetic receptor allowing exquisite naked-eye selective recognition of glyphosate.
A Dinuclear Copper Based Artificial Metalloenzyme for the Kinetic Resolution of Adrenalin
Authors: Rossel Thibaud
Published: April 2020

Incorporation of a copper catalyst within carbonic anhydrase affords artificial metalloenzyme for the oxidation of catechols in aqueous solution at physiological pH. Optimization of the performance can be achieved either by chemical or genetic means. In addition, a model of enzyme/inhibitor is proposed and discussed.
Time-Resolved Non-Invasive Metabolomic Monitoring of Microﬂuidic Spheroid And Monolayer Cell Cultures By NMR
Authors: Patra Bishnubrata , Sharma Manvendra , Hale William , Utz Marcel
Published: April 2020

We present a quantitative NMR study comparing the metabolic activity in a spheroid and a monolayer of the same number of MCF-7 cells. Both cultures were carried out under hypoxic conditions on microfluidic devices with 2.5 µL sample volume. NMR spectra were obtained by periodically inserting the devices into a dedicated micro-NMR probe. The results demonstrate that quantitative, non-invasive metabolomic monitoring of microfluidic cultures with as few as 1250 individual cells is possible. Metabolite concentrations in the cultures were found to change linearly with time. The consumption rates of D-Glucose and the production rates of L-Lactic acid were approximately 2.5 times larger in the monolayer than in the spheroid. In contrast to the spheroids,

monolayers exhibited significant production of L-Alanine and L-Glutamine. Due to its non-invasive nature, metabolic monitoring by NMR can complement destructive fluorescent-based assays that are commonly used for read-out in microfluidic cultures.
Amorphous Mixtures of Ice and C60 Fullerene
Authors: Halukeerthi Siriney , Shephard Jacob J. , Talewar Sukhpreet , Evans John S. O. , Rosu-Finsen Alexander , Salzmann Christoph
Published: April 2020

Carbon and ice make up a substantial proportion of our Universe. Recent space exploration has shown that these two chemical species often coexist including on comets, asteroids and in the interstellar medium. Here we prepare mixtures of C60 fullerene and H2O by vapor co-deposition at 90 K with molar C60:H2O ratios ranging from 1:1254 to 1:5. The C60 percolation threshold is found between the 1:132 and 1:48 samples, corresponding to a transition from matrix-isolated C60 molecules to percolating C60 domains that confine the H2O. Below this threshold, the crystallization and thermal desorption properties of H2O are not significantly affected by the C60, whereas the crystallization temperature of H2O is shifted towards higher temperatures for the C60-rich samples. These C60-rich samples also display exotherms corresponding to the crystallization of C60 as the two components undergo phase separation. More than 60 volume percent C60 is required to significantly affect the desorption properties of H2O. A thick blanket of C60 on top of pure amorphous ice is found to display large cracks due to water desorption. These findings may help understand the recently observed unusual surface features and the H2O weather cycle on the 67P/Churyumov–Gerasimenko comet.
Shattering During Surface-Induced Dissociation: An Examination of Peptide Size and Structure
Authors: Barnes George , Shlaferman Amanda , Strain Monica
Published: April 2020

We present the results of direct dynamics simulations of surface-induced dissociation for AnK, KAn (n = 1, 3, and 5), AcA7K, and AcKA7 for collisions with a fluorinated self-assembled monolayer surface. Our focus is on elucidating shattering fragmentation events, which takes place in coincidence with the collision event and frequently occurs in a charge remote fashion. Shattering events typically generate a large number of fragmentation products, and hence, are not easily understood through chemical intuition. Our simulations show distinct differences between the AnK/AcA7K and KAn/AcKA7 series of peptides, with the former being more reactive, while the latter is more selective regarding the type of bond that will break. In addition, we examine the possible backbone rearrangements seen as well as sidechain fragmentation.
Analysis of discriminatory game variables between winners and losers in women’s handball world championships from 2007 to 2017
Authors: de Paula Leandro V. , Costa Flávia E. , Ferreira Renato M. , Menezes Rafael P. , Werneck Francisco Z. , Coelho Emerson F. , Greco Pablo J.
Published: April 2020

The aim of this study was to identify game variables that discriminated winning
from losing teams and to understand how these variables contributed to victory by
observing goal differences in matches of the women’s handball world championships.
The sample comprised 471 WCh’s games played between 2007 and 2017. The games
were grouped into three clusters: balanced games – difference of 1-8 goals;
unbalanced games – difference of 9-20 goals; and very unbalanced games –
difference of > 20 goals. Generally, the performance of winning teams was
significantly higher (in most variables), or lower in the case of the number of
technical faults (p<.05). In the balanced games, there was a greater
contribution of defensive variables (stolen balls, blocked throws, and
goalkeeper’s efficiency indicators) in relation to attack variables (attack efficiency
and throw efficiency indicators). For victory, the number of technical faults reduce
the chances of winning. Games with the unbalanced and very unbalanced goal
differences seem to follow the same tendency; however, in the very unbalanced
games, there were more assists, yellow cards and 2-min suspensions. We concluded
that the decisive variables for victory in the balanced games showed a greater
weight, with a special emphasis on stolen balls followed by offensive variables
(throw efficiency indicators, attack efficiency, and technical faults). There was
an equal tendency for the games with unbalanced and very unbalanced outcomes.
Relationship between Active Physical Exercise And Sleep Quality With Physical Fatigue in Elderly
Authors: Ismahmudi Ramdhany , Fakhrurizal Alfi Ari
Published: April 2020

Physical exercise is any form of activity carried out by an individual, especially the elderly, to improve physical fitness and physical conditions, with the main objective being to increase strength, cardiorespiratory endurance, speed, skills,, and flexibility. In the elderly, physical training aims to improve the quality of life, so they can get through their old days in a fit. The purpose of this study is to find out how the relationship between active physical activity and sleep quality with physical fatigue that occurs in the elderly in the working area. This research is a descriptive qualitative study using a cross-sectional study approach. Sampling is done by the method of Total Sampling, where all respondents will be involved in research activities, with a total sample of 125 respondents. The research activity was carried out for approximately 1 month starting from July 23-August 24, 2019 at the Harapan Baru Health Center in Samarinda. The result of this research showed the significant relationship between physical activity with fatigue.
The Effectiveness of Prezi Web-Based Teaching Media to Improve Nursing Students’ Comprehension
Authors: Yanto Arief , Warsono Warsono
Published: April 2020

The process of nursing education requires a teaching media which straightforward to be comprehend. Inappropriate determining the teaching media leads nursing students face difficulties to receive an adequate course’s guidance from the educators. Prezi is a web-based presentation program which comprehensively integrates text, picture, animation, video and audio into one presentation file. This study is aimed to determine the effectiveness of Prezi web-based teaching media on improving nursing students’ comprehension. A quantitative-experimental method with pretest-posttest control group design was applied. A total of 176 nursing students were recruited by using non probability sampling approach. The study indicated Prezi web-based teaching media showed significant result on improving students’ knowledge. The determination of Prezi web-based program is suggested to improve students’ comprehension in nursing education.
Riscos e Conflitos Socioambientais de Oleodutos no Perímetro Urbano de Mossoró/RN
Authors: Nascimento Francisco Gilson do , Diodato Marco Antônio , Grigio Alfredo Marcelo
Published: April 2020

As interações entre os riscos e conflitos de oleodutos, na cidade de Mossoró/RN, se dá perante o uso e ocupação do solo pelos agentes sociais, grandes transformadores deste espaço. O presente artigo analisa os riscos e os conflitos associados ao uso e ocupação do solo em áreas de oleodutos no perímetro urbano de Mossoró/RN, abrangendo análise da presença de oleodutos frente a possíveis riscos e conflitos na área urbana e identificação da classe de uso e ocupação com maior grau de risco a vazamentos de oleodutos. O uso de Sistema de Informações Geográficas - SIG permitiu a geração de informações georreferenciadas e especializadas da paisagem, por meio de mapas e buffers de interferências às classes de uso e ocupação do solo urbano da cidade. Os resultados mostraram que a classe de uso residencial, comercial e serviços apresenta-se como a maior área susceptível a riscos e conflitos por meio da interferência de oleodutos na área urbana (31,13%). Nesse sentido, espera-se que o estudo possa servir como um instrumento delineador nas tomadas de decisões pelo poder público e possibilite mitigar possíveis danos à saúde e as perdas causadas por esses fatores a partir de ações preventivas. Risks and socioenvironmental conflicts of oil pipelines in the urban perimeter of Mossoró-RN A B S T R A C TThe interactions between the risks and conflicts of pipelines in the city of Mossoró / RN are due to the use and occupation of the soil by the social agents, great transformers of this space. The present article analyzes the risks and conflicts associated to the use and occupation of the soil in pipeline areas in the urban area of Mossoró / RN, including analysis of the presence of oil pipelines in face of possible risks and conflicts in the urban area and identification of the class of use and occupation with a higher degree of risk to pipeline leaks. The use of Geographic Information System - GIS allowed the generation of georeferenced and specialized information of the landscape, through maps and buffers of interferences to the classes of use and occupation of the city's urban soil. The results showed that the residential, commercial and services class is the largest area susceptible to risks and conflicts through pipeline interference in the urban area (31.13%). In this sense, it is hoped that the study can serve as a delineating tool in the decision making by the public power and make it possible to mitigate possible damages to health and the losses caused by these factors from preventive actions.Keywords: Conflicts. Geoprocessing. Urban Planning. Use and Occupation.
Relação Entre o Total de Raios e os Raios Nuvem-Solo Sobre o Leste da Amazônia
Authors: Sodré Giordani Rafael Conceição , Ferreira Douglas Batista da Silva , Ventura Juarez Oliveira , Costa Cláudia Priscila Wanzeler , Souza Everaldo Barreiros , Moraes Bergson Cavalcanti
Published: April 2020

Neste estudo foi realizada uma análise comparativa da ocorrência de raios do tipo nuvem-solo (NS), medidos por sensores em superfície e o total de raios (NS e intra-nuvem - IN), derivados de sensoriamento remoto por satélite, objetivando estabelecer uma proporção dos raios NS entre ambos os Lightning Location System (LLS) para o leste da Amazônia. Foram utilizados dados da STARNET e do banco de dados LRTMS (OTD/LIS). A metodologia de análise consistiu no cálculo da Razão Z, da Proporção de Incidência de Raios NS e da Correlação de Pearson. Adicionalmente também foi realizada uma investigação sobre a relação da quantidade de raios NS em função da altitude do relevo. Os resultados apontaram que a incidência de raios NS tem uma oscilação média mensal de 7,5% a 20,4% do total de raios medidos por sensoriamento remoto e a quantidade varia de acordo com o tipo de superfície, sendo que na região oceânica observou-se baixa incidência de raios NS, nas regiões mais próximas ao litoral observou-se no primeiro semestre os maiores valores da proporção de incidência de raios NS, enquanto que no interior do continente, o máximo de atividade elétrica do tipo nuvem-solo apresenta maiores percentuais durante o segundo semestre. Também foi constatado que o relevo não altera a proporção de incidência dos raios NS, uma vez que não foi encontrada uma relação direta somente com a altura do relevo. Relationship Between Total Lightning and Cloud-To-Ground Lightning in Eastern AmazoniaA B S T R A C TAn analysis of the occurrence of cloud-to-ground (CG) lightning, measured by ground-based sensors, and total lightning (CG and intra-cloud (IC) lightning), detected by satellite remote sensing, was performed in this study to compare the proportion of CG lightning between the two lightning location systems (LLS) in Eastern Amazonia. STARNET and LRTMS (OTD/LIS) data were used. The method of analysis consisted of calculating the Z ratio, the proportion of incidence of CG lightning and the Pearson correlation coefficient. Furthermore, the variation in the number of CG lightning flashes as a function of terrain altitude was also investigated. The results indicated that the mean monthly CG lightning incidence ranges from 7.5% to 20.4% of the total lightning measured by remote sensing and that the number of CG lightning flashes varies according to surface type. More specifically, the oceanic region showed low CG lightning incidence, with the regions closest to the coast having the highest proportion of CG lightning incidence in the first semester; in contrast, the CG electrical activity peaked inland during the second semester. The results also showed that the terrain had no effect on the proportion of CG lightning incidence because no direct relationship with terrain height alone was found.Keywords: Proportion, Z Ratio, Terrain Altitude.
Nutrients demand of cactus forage
Authors: Moreira João Macedo , Pérez-Marin Aldrin P. , Araújo Jucilene Silva , Lambais George Rodrigues , Sales Aldo Torres
Published: April 2020

The study aimed to evaluate the efficiency of nutrient use in three cactus forage (CF) cultivars (Opuntia stricta and Nopalea cochenillifera), 365 days after planting under different types of fertilizer in two research sites (Condado and Riachão) of the semi-arid region of Paraiba state, Brazil. The experimental design was a randomized block design with treatments in a factorial scheme (3×4), three cultivars of CF (Orelha de elefante Mexicana; Miúda; Bahiana), and four fertilizer treatment (Control; Manure; Manure with Nitrogen; Mineral fertilization) with four replications. The CF cultivars did not differ significantly in nutrient use. That means of physio-logical efficiency by CF cultivars were 1.62, and 2.36 kg of biomass per kg of nutrient applied in Condado and Riachão, respectively. The efficiency of nutrient recovery was 16% for the Condado, according the following order: K> P> Ca> N> C = Mg and 12% for Riachão: K> P> N> C = Ca = Mg. In the two research sites, the treatment with mineral fertilization significantly increased the efficiency use of N, P and K in comparison to the other treatments. The average for efficiency of nutrient utilization was 25% and 19% for Condado and Riachão, respectively, in the following order for Condado: K> P> N> Ca = Mg> C, and Riachão: K> P> N> C> Mg = Ca. In a CF production system aiming to obtain a yearly harvest cycle, it is necessary to replenish of K and P to maintain the nutritional balance between the soil and CF plant.
Testing Of The Validity of Interactive Learning Module on Creative and Entrepreneurs Learning Products
Authors: Sefriani Rini , Wijaya Indra , Menrisal Menrisal , Dewi Muharika
Published: April 2020

This study aims to determine the level of validity of Interactive Learning Modules in Creative Product and Entrepreneurship Subjects in Vocational Schools. The method used in this research is the 4-D Research and Development method. The steps of this research and development method are: (1) define, (2) design, (3) develop, and (4) assess. Based on research that has been done, the average value of the validator test assessment of the Creative Learning and Entrepreneurship Interactive learning module is 91.92%, so that the level of validity can be interpreted very validly used. In conclusion, based on the assessment and input from experts that the Interactive Learning Module on the subject of Creative Products and entrepreneurship in High Schools and Vocational Schools is feasible to be used in learning Creative Products and Entrepreneurship in Vocational High Schools.Â Â
Hybrid Learning Design to Minimize Academic Stress of Digital Nativesâ€™ Generation in Accounting Course
Authors: Mucshini Binti , Siswandari Siswandari
Published: April 2020

The digital natives generation (DNG) tends to experience relatively high academic stress if the learning design does not pay attention to its characteristics and culture. This study aims to develop a prototype of a hybrid learning model to minimise such stress amongst prospective accounting teachers. This hybrid learning design combines face to face and online learning using the Design-Based Research (DBR) method with stages of problem analysis when learning, and the development of solutions based on principles and theory. Questionnaires, interviews, FGDs and literature studies were used to collect data which were analysed using quantitative and qualitative descriptive analysis. The study found that the DNG experiences relatively high academic stress in the accounting context, so it is necessary to develop a prototype of a flipped classroom-type hybrid learning model by considering its learning style and academic culture and based on the sociocultural revolution theory. This hybrid learning design remains to be tested in further research for its feasibility and effectiveness in minimising DNG academic stress.
Mediation Effect of Assessment as Learning in Mobile-Based Module on Vocational Education Studentâ€™s HOTS
Authors: Darmawan Fitrah Asma , Jaedun Amat
Published: April 2020

This study aims to find out the mediation effect of assessment as learning (AaS) model in a mobile-based module upon studentsâ€™ higher-order thinking. This study is a Research and Development (R & D) and Experimental research. R&D method consisted of: information gathering, product planning, product development, product validation, preliminary test, limited trial, revision, product implementation, and dissemination. The experimental method was one-group time-series design. Data is gathered by using the online assessment sheets. This study employed 40 students of vocational high school. The interpretation of higher-order thinking improvement is based on the criteria of value gain. In addition to calculating the gain score, this study uses a hypothesis. The hypothesis is tested by comparative two samples technique. The result shows that assessment as learning model in mobile-based module has improved studentâ€™s higher order thinking skills. The teacher needs to consider the use of the assessment as learning model on the learning module.
Practical Learning Innovation: Real Condition Video-Based Direct Instruction Model in Vocational Education
Authors: Warju Warju , Ariyanto Sudirman Rizki , Soeryanto Soeryanto , Hidayatullah Rachmad Syarifudin , Nurtanto Muhammad
Published: April 2020

This study aims to improve student learning outcomes through the implementation of direct learning models that are supported by learning videos. Class action research refers to Kemmis and McTaggart's designs, which are carried out over two cycles. The subjects of the study were students of class X LVE 7 at VHS Dharma Bahari Surabaya. Data were collected using test and observation instruments. Test and observation data were analyzed descriptively based on standardized study completeness criteria. The results of this study found that student learning outcomes consistently increased from the pre-test scores, the value of the first cycle, to the value of the second cycle. Based on the pre-test score data, it is known that there are 16 or 53% of 30 students who reach the complete category. Learning outcomes are then improved in the first cycle, where there are 19 or 63% who reach the complete category. Meanwhile, in cycle II there were 23 or 77% of students who reached the complete category. This increase occurred consistently so that it was concluded that the use of direct learning models supported by learning videos was very effective for the learning of class X LVE 7 students at VHS Dharma Bahari Surabaya.
HUBUNGAN ANTARA SELBSVERTRAUEN DAN SPRECHFERTIGKEIT BAHASA JERMAN SISWA KELAS XI SMA NEGERI 8 MAKASSAR
Authors: Nurlina Nurlina , R. Mantasiah , Azizah Laelah
Published: April 2020

Abstract. This research was conducted to obtain data and information about the relationship between Selbsvertrauen and Sprechfertigkeit German Language Class XI students of SMA Negeri 8 Makassar. The variable in this study is Selbsvertrauen and the dependent variable is Sprechfertikgeit. The population in this study were all class XI of SMA Negeri 8 Makassar consisting of 3 classes, the sample in this study were students of class XI MIPA 2 at SMA Negeri 8 Makassar with a total of 35 people. The results of this study obtained the results of speaking skills and questionnaire tests. Based on the results of the study indicate that the R count is greater than the R table (0.796 <0.334). The analysis showed that there was a relation between Selbsvertrauen and Sprechfertigkeit German Language Class XI students at SMA Negeri 8 Makassar.
Karakteristik Bahan Ajar IPA Terpadu Berbasis Kontroversi
Authors: Sudarto Sudarto , Tawil Tawil
Published: April 2020

Integrated science learning is the latest science learning icon and is recommended in the national curriculum at all levels of education. Integrated learning is essentially a learning that allows students both individually and in groups to actively seek, explore / explore, and find concepts and principles holistically and authentically. Science as a subject should be taught in its entirety between the study of Physics, Chemistry, and Biology. Facts on the ground show that science learning so far in various levels of education is generally not integrated. The ongoing learning process still indicates the presence of Physics, Chemistry, and Biology subjects. This happens because of various things, including the absence of representative integrated science teaching materials. Subjects or respondents in this study were students of the Natural Sciences Study Program FMIPA UNM 2014 Class Regular Class. The number of respondents was 28 people. This research was conducted in Odd semester 2016/2017 academic year. This research is classified as development research. The results of this study in the form of the characteristics of integrated science teaching materials based on controversy that has been developed which includes: contains a title that is controversial; arranged with integrated, integrated, and shared integration; arranged with a principle that in preparing the teaching material always involves physical, chemical, and psychological material; unique and creative; its contents are easy to understand like reading a short story; fun to read; open mind; the title of the material is intriguing; as if the material in teaching materials is human-like character; can increase creativity; the title of the material attracts attention; the contents are interesting; the language used is beautiful and unique; can come up with creative ideas; not boring; and increase imagination and thinking ability.
Peningkatan Kinerja Guru Dalam Menerapkan Model Pembelajaran Contextual Teaching And Learning (CTL) Melalui Kegiatan Supervisi Klinis
Authors: Samilwati Samilwati
Published: April 2020

. This study aims to determine the improvement of teacher performance in learning using the CTL learning model through clinical supervision in the Assistance Region I Kindergarten Pole Elo Mare District Bone Regency. This research is a School Action Research, because the research was conducted to solve the problem of the learning process at school and was carried out in 2 cycles with 2 meetings in each cycle. Based on the data analysis of the results of the study showed that the implementation of classroom supervision by the principal proved successful in improving teacher performance in managing the learning process by applying the contextual teaching and learning (CTL) learning model as evidenced by the increase in the results of observations made at 3 appraisers. In the aspects of the assessment of the Learning Implementation Plan (RPP) increased from 54.46 to 75.60 and 94.35 while the aspects of the assessment of the ability to plan learning increased from 54.63 to 70.83 and 87.96 and aspects of the ability to carry out learning, evaluation, and action continued from 55.77 to 68.91 and 81.73 at the end of the second cycle. Thus it can be concluded that the implementation of clinical supervision has proven to be effective in improving teacher performance in the Assistance Region I Kindergarten Pole Elo Mare District Bone in 2019 in applying the contextual teaching and learning (CTL) learning model.
Peningkatan Kemampuan Guru Dalam Pengembangan Silabus Dan RPP Melalui Pola Pembinaan Profesional Dengan Pendekatan Kooperatif
Authors: Sommeng Andi
Published: April 2020

Research on improving the ability of teachers in the development of syllabus and lesson plans through professional coaching patterns with a cooperative approach in the Assisted Region III of SD Negeri 112 Pacciro in 2018. This type of research is action research with 4 stages, namely planning, implementation, observation and reflection. The research subjects were 8 teachers in the Assisted Region III Elementary School 112 Pacciro in the 2018 school year. Data collection techniques were carried out with observation and documentation. Data validation uses triangaluation techniques. Data analysis uses descriptive techniques. The results showed an increase in the ability of teachers in the development of the syllabus and planning for the implementation of learning increased from an average value of 49.59 with criteria of under-grade values at the initial condition, to 69.98 criteria for sufficient grades in the first cycle and to become 89.47 criteria for very grades good in the second cycle. The conclusion is that the pattern of professional coaching with a cooperative approach is proven to be able to improve the ability of teachers in the development of syllabus and RPP in the Binaan III Regional SD Negeri 112 Pacciro in 2018.
Hubungan Konsep Diri Dan Motivasi Belajar Dengan Kemampuan Berpikir Divergen Biologi Siswa SMA Negeri 1 Makassar
Authors: Sunaryati Sunaryati , Lataami Arif
Published: April 2020

The objectives of the research were to discover (1) the correlation of self concept towards divergent thinking ability of the students at SMAN 1 Makassar; (2) the correlation of motivation towards divergent thinking ability of the students at SMAN 1 Makassar; (3) the correlation of self concept and motivation toward divergent thinking ability of the students at SMAN 1 Makassar. The research was Ex-post facto research. The population of the research was all of the students at SMAN 1 Makassar. The samples of the research were 240 students taken by purposive sampling technique. The variables of the research were: (1) independent variables consisted of self concept and learning motivation and (2) dependent variable namely divergent thinking ability test to the students of SMAN 1 Makassar. The results of the research showed that self concept and learning motivation simultaneously had positif correlation toward divergent thinking ability
The Influence of Current Ratio, Quick Ratio and Net Profit Margin on Return on Investment at PT. Telekomunikasi Indonesia (Tbk)
Authors: Susanti Neneng
Published: April 2020

Financial management is very influential on the continuity of activities and the existence of a company and also affects every individual in the company. This study aims to determine the effect of the current ratio, quick ratio and net profit margin on return on investment at PT. Telekomunikasi Indonesia (Tbk) 2014-2018. The method used is explanatory research with a sample of 5 years of financial statements that have been made panel data. The analysis technique uses statistical analysis with regression testing, correlation, determination, and hypothesis testing. The results of this study the current ratio does not significantly influence the return on investment of 50.7%, the hypothesis test obtained a significance of 0.177> 0.05. The quick ratio does not significantly influence the return on investment of 51.4%, the hypothesis test obtained significance of 0.173> 0.05. Net profit margin has a significant effect on the return on investment of 86.6%, hypothesis testing obtained significance of 0.022 <0.05. The current ratio, quick ratio, and net profit margin simultaneously have a significant effect on the return on investment of 99.2%, hypothesis testing is obtained 19,836> 9,280..