bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of temperature on presepsin assessment in biological fluids
Authors: Botondi Valentina , D'Adamo Ebe , Trubiani Oriana , Gazzolo Diego
Published: January 2024

Thermal stabilization is important for assuring a sample quality and prevent protein denaturation. Presepsin is a new reliable biomarker of sepsis produced in response to bacterial infections. However, before its inclusion into clinical practice several criteria need to be fulfilled. One of these regards the samples thermostability after a long-term refrigeration in different biological fluids (blood, urine, saliva) that can constitute a confounding factor for Presepsin reliability as diagnostic test. On this light, this review offers an update of studies analyzing presepsin after sample thawing.
STING agonists in cancer immunotherapy: a brief review
Authors: Ceci Martina , Trerotola Marco , Iezzi Manuela
Published: January 2024

The “STimulator of INterferon Genes” (STING) represents the primary sensors of cytosolic double-stranded DNA (dsDNA). The STING cellular signaling pathway is considered an attractive pharmacological target for cancer immunotherapy due to its immunostimulatory potential. In fact, activation of the intracellular STING protein triggers the secretion of type I IFNs, which results in immune-mediated tumor elimination and generation of antitumor immune memory. Two types of STING agonists were developed: cyclic dinucleotides (CDNs) and non-nucleotide small molecule agonists. Preclinical studies of STING agonists have demonstrated remarkable results in many tumor models, resulting in complete and durable therapeutic responses in a majority of treated mice. This review provides a brief summary of the latest research findings on STING agonists, their delivery to the tumor and the strategies being employed to enhance their efficacy in cancer immunotherapy.
Clinical efficacy of cord blood platelet gel in chronic limb-threatening ischaemia patients: a case series
Authors: Mastrangelo Giovanni , Santodirocco Michele , Semerano Luigi , Palena Giancarlo , Sciannelli Vincenzo , Magistro Gabriele , Marinucci Roberto , Di Sebastiano Pierluigi , Palazzo Vincenzo
Published: January 2024

The cord blood platelet gel (CBPG), rich in growth factors and chemoattractans molecules, is a useful tool to treat lesions with tissue loss as it accelerates remission and ensures the functional recovery of the limb. The results obtained in a series of 10 patients treated at the “Fondazione IRCCS Casa Sollievo della Sofferenza” in San Giovanni Rotondo (Italy) with CBPG in the treatment of revascularized patients with chronic limb-threatening ischemia (CLTI) are presented here. In the period 2017-2021, they were treated with surgical toileting of the ulcers and application of CBPG. As a general scheme, CBPG was applied once every 21 days for 3 times; 8 out of 10 patients observed had diabetes mellitus, of these 4 were on insulin therapy. One patient underwent a major amputation; two patients died for non-infectious causes. Studies in the literature show that CBPG is safe for patients affected by CLTI and undergoing revascularization, promoting faster healing. Our results appear to overlap this data, also showing CBPG as an effective therapeutic option for the treatment of vascularized patients with foot lesions for CLTI, reducing the risk of major amputation. In perspective, multicenter randomized studies are needed to evaluate immediate and late results.
Ambulatory blood pressure and risk of heart failure: a mini-review
Authors: Coccina Francesca , Scurti Rosa , Trubiani Oriana , Pierdomenico Sante D.
Published: January 2024

The aim of this mini-review is to report current knowledge about the association between ambulatory blood pressure and risk of heart failure in hypertension. We conducted a literature search through PubMed, Web of science and Cochrane Library by using terms such as ambulatory blood pressure, 24-hour blood pressure, daytime blood pressure, nighttime blood pressure, hypertension, heart failure. We identified 4 studies including 7891 patients who developed 260 cases of heart failure during the follow-up. The evaluation of published studies indicates that ambulatory blood pressure is superior to clinic blood pressure in predicting the occurrence of heart failure. Particularly, it has been reported that 24-hour blood pressure values, nighttime nondipping blood pressure pattern and ambulatory resistant hypertension are associated with increased risk of heart failure above clinic blood pressure. Nevertheless, there are still few data in the literature on this topic. Therefore, further studies are needed to broaden our knowledge on this matter to improve our therapeutic approach to prevent HF in hypertensive patients.
The implant loading influence on crestal bone remodelling around hybrid titanium implants: a prospective clinical study
Authors: Falconio Luigi , Valente Francesco , Mavriqi Luan , Trubiani Oriana , Traini Tonino
Published: January 2024

The aim of this work was to analyze the changes of the mesial and distal cortical bone peaks around the hybrid titanium implants in relation to the masticatory load up to 7 years of follow-up. The analysis aims how occlusal loads may affect the peri-implant bone years after insertion through two-dimensional analysis using intraoral digital radiographs. Twelve hybrid T3 implants (Biomet 3i) were placed in 9 healthy patients with the 2-stage surgical approach. Standardized digital Rx were taken after early loading (6-8 weeks) after placement (T0); after 12 months (T1); after 30 months (T2); after 4 years follow-up (T3), after 5 years follow-up (T4), after 6 years follow-up (T5), after 7 years follow-up (T6). The marginal bone gain and loss was digitally measured. From T2 to T4 (5 years follow-up) there was a new bone formation demonstrating that well-balanced load forces can ensure good maintenance, with a crestal bone gain during the 2.7 to 7-year follow-up period.
L’uso delle mappe concettuali per lo studio delle dipendenze da internet: una Unità didattica
Authors: Di Giuseppe Lidia
Published: January 2024

The article provides an account of a research/Teaching unit that took place in a Classical High School in Rome. It began at the end of the I year and developed in the I quarter of the II year, divided into two phases, as part of the Civic Education lessons. The first purpose was to make students aware of the problems of Internet addiction, to make them self-conscious of the risks that they can run, especially following a period of pandemic, which has forced the entire Italian (and world) population to confinement at home. The second purpose was to test whether the use of concept maps was indeed useful in producing in students the desired knowledge about Internet Addiction Disorder. Concept maps were created first on research made independently by the students, then through a summary on the topic provided by the teacher. After each of the two steps, the same questionnaire was administered: the results were finally compared. It turned out that, in the transition from Step I to Step II, new learning had indeed occurred. The learning experience was fully satisfactory, and the pupils themselves confirmed that the concept maps helped them to organize and deepen the new knowledge they were acquiring.
Orientarsi nel digitale e comprendere i social media, tra percezioni e uso reale. Una ricerca-azione nel savonese per l’educazione digitale nelle scuole secondarie di secondo grado
Authors: Lugaro Gabriele , Di Bari Cosimo , Ferro Jacopo
Published: January 2024

The article describes the outcomes of an action-research conducted with adolescents to investigate their perceptions and actual uses of digital technologies and social networks. The course, carried out with 450 pupils of a secondary school, involved the administration of a questionnaire to collect data and obtain material to proceed to critical reflections and useful workshop activities to improve the perception of the time spent with touchscreen devices and especially with the smartphone and to encourage a more conscious and more critical use of these tools. In the second phase of the research, in fact, through a problematizing attitude, the data were examined and analyzed by both learners and teachers, detecting a desire on the part of adolescents to improve their modes of use and a need on the part of teachers to explore these issues in greater depth.
The age of Pompei. Progettazione di un percorso di didattica museale immersivo e gamificato
Authors: Gaggioli Cristina , Mancini Chiara
Published: January 2024

The contribution proposes a reflection on the design of educational paths in immersive environments, starting with the presentation of “The age of Pompeii,” an immersive and gamified museum educational path, aimed at increasing the dialogue between the artistic-cultural heritage of the archaeological park of Pompei and children under 18. The contribution describes the characterizing design elements of the educational path, with particular reference to those concerning learning design, universal design and game design. The challenge is to be able to identify the elements that can make an immersive learning environment not only educational, but also engaging and inclusive.
Places 'out-of-place'
Authors: Fierro Maria
Published: January 2024

In the frantic drive where the city extends into the world, and the world takes shape within the cities through migratory processes, we witness a multiplication of hybridisations, co-existences and conflicts. This gives way to kaleidoscopic landscapes in which, however, two polarities can be recognised: exclusivity and exclusion. It is the city of the rich and the city of the poor (Secchi 2013) that becomes more complex with ‘certain bodies [and] out of place’ multiplying the topographies of the other. This article, part of a PhD dissertation in progress, describes the case of Roma communities, and investigates ‘out-of-place’s’, emblems of urban exclusion generically called ‘Roma camps’, that corrode the idea of order and decorum. It describes, from an urban point of view, the phenomenon of encampment in its specification into a control device or an informal practice. Both such different urban configurations are investigated through a case study: a precise urban transect in the northern area of Naples in which both coexist, the informal settlement of Cupa Perillo and the Village of Solidarity in Secondigliano. This reveals latent conditions finding, in the informal configurations, alternative systems of rules that may suggest new spaces of utility to a project eschewing the narratives of a single history, the one that has produced control devices and urban expulsions.
Bodies and spaces of insanity. Towards a new bond of care between the territory and psychiatric vulnerabilities
Authors: Rossi Maddalena
Published: January 2024

The paper reflects about the relationship between space and the body affected by psychiatric vulnerability. In 1978, with Law no. 180, Italy, the first nation in the world, closed psychiatric hospitals and established a system of treatment for mental discomfort widespread in the territories. However, this system has not yet been implemented and, at the same time, especially as a result of the CoViD-19 outbreak, psychic vulnerability continues to grow. In this perspective, the paper questions what new links of care can be woven between territory and mental health. It presents a survey on how the relationship between bodies (with particular regard to the female ones) and madness developed in Italy, through the reading of spatial – architectural and urban – devices which, since the birth of the psychiatric discipline in the mid-nineteenth century, have been used over time to ‘manage’ mental illness. The reflections here proposed dialogue with urban planning, summoning it to deal with the concept of ‘city that care’, understood as a project of mental health and social cohesion based on a new ‘alliance among bodies’ and between them and territorial resources.
Towards a shared re-signification of space: the ethics of care in feminist commoning
Authors: Brunori Francesca , Musso Virginia
Published: January 2024

By adopting a conception of care that transcends the reproductive and domestic dimensions to invest the public and political ones, the article aims to highlight the relevance of care practices in feminist commoning experiences, in order to demonstrate how they can represent an alternative way of inhabiting public and private space, subverting the capitalist system that increasingly erodes the right to the city. After a critical discussion of the systemic characteristics that define contemporary cities - dominated by visions and logics that increase the complexity of sharing spaces and accessing primary resources - the experiences of commoning are presented. These experiences, conceived as the territorialisation of care practices, allow us to imagine strategies to respond to the current crisis also through the creation of threshold places, in which the private and public dimensions are hybridised. In this context, the experiences of Lucha y Siesta and Plaza Las Pioneras, located in a transformative horizon that appeals to the need and not the demand for space, are taken as models for re-inhabiting the city in alternative ways, based on social and economic equity, as well as interdependence and networking.
Editorial
Authors: Belingardi Chiara , Poli Daniela
Published: January 2024

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Dispute Resolution Methods, Fundamental or Human Rights and Legal Pluralism
Authors: Damiani di Vergada Franzetti Enrico
Published: January 2024

The analysis of modern political-institutional systems, democratic-constitutional of a liberal mold, if it clarifies the reasons for the presence and diffusion of dispute resolution methods (state awards), of fundamental and human rights (general) attributable to the new elites of power and government, therefore to the bourgeois class, in the context of a monistic and statistic conception of legal systems, then does not explain the reasons for the diffusion and progressive multiplication of alternative methods of resolving disputes, such as fundamental or human rights in more recent eras. It is therefore necessary to analyze the processes of change that have affected the State, the law, the judicial systems, therefore the fundamental and human rights and the methods of resolving disputes in the light of the phenomenon of legal pluralism.
From Mathematical Theory of Communication to Network Society: a Sociological Transformation
Authors: Petroccia Sara
Published: January 2024

An increasing pace of innovation in telecommunications, information technology has facilitated our society’s transition into what is called the “Information Age”. This work is intended to offer a means of understanding current directions in digital innovation. In 1948, the general theory for electronic communications (Shannon 1948), contributed to a substantial reorganization of our society; some fifty years later, Castells attempts to grasp the relationships between emerging technical, economic, political and cultural trends and helps us understand the processes of change triggered by the convergence of information and communication technologies (ICTs). In this work, starting from the interdisciplinary literature, the main theoretical and practical contributions leading to technological convergence are investigated in order to open a window on the contemporary landscape in semantic web, algorithmic reasoning and social intelligence (Esposito 2022). The resulting framework, although due to the dynamism of the phenomena under consideration, is not meant to be an exhaustive analysis of the relationship between digital tools and society, it rigorously summarizes many of the major technical and social issues open today and, in view of the future expansion of the ICT ecosystem, underscores the urgent need for conscious citizen participation in the information society.
The Smart Society and Its Enemies. Meanings and Limits in the Criticism of Smartness
Authors: Susca Emanuela
Published: January 2024

Distancing myself from unreflective appropriations, in this article, I trace a brief history of smartness by dwelling mainly on the differentiation of smartness itself from intelligence, digitization or simple competitiveness to propose an idea that focuses on the integration of people, environment, and technologies. Moreover, after analyzing some not insignificant misgivings about the delimitation of places and relations, I offer some useful elements to distinguish progressive criticism, which aims at the empowerment of the majority, from merely regressive and ultimately unhelpful criticism. I conclude by pointing out that smartness, in addition to helping the social sciences, particularly sociology, frame fundamental and still unresolved issues in new ways, is now an unavoidable topic for researchers.
The Smart Society Between Semantic Indefiniteness and Efficientistic Reductionism
Authors: Sessa Melissa
Published: January 2024

The article aims at the construction of an annotated bibliography on the smart society. the impression, and therein lies the cognitive hypothesis, is that the bibliography on the subject is technical and sectoral. the consequences of this technicality and the semantic difficulty that smartness brings, seen to result in a strong impoverishment of the social.
Costituzione, ieri e oggi
Authors: Nevola Gaspare
Published: January 2024

Constitutions represent an answer to a problem that derives from the nature of human beings and from their co-living together in a common social and political space. The root of the “constitutional problem” can be summed up with the following double question: how to create a stable and safe human/political community for zoon politikon, inside of a given territory, under a political organization flexible enough to adapt to internal and external changes which can threaten stability and security of collective coexistence? And how to do it between order and freedom, between power and law, between consent and dissent, between majority and minority? The present essay examines conceptual, empirical and historical profiles concerning the constitutional matter which has engaged the Ancients as well as the Moderns and Contemporaries. The essay emphasizes, on one side, the transformations of constitutions, on the other side, the intrinsic nature of constitutions in terms of “sociopolitical contract” and the normative telos that characterizes them. In contemporary societies, the Occidental ones in primis, the constitutional telos stay wrapped up, more than in the past, in an intimate (and conflictual) interweaving between formal (or encoded) constitution and “material” constitution “practiced” in social, cultural and political life. One might say that men do their constitutions, but not at will: systemic dynamics and structures (social and cultural, economics and technological, juridical and political) matter.
Comunicazione autorevole e disintermediazione. Mutazioni prossemiche del post-pandemia
Authors: Bellini Pier Paolo
Published: January 2024

The pandemic has not only affected our bodies (biological dimension) and our minds (psychological dimension): it has also left a profound mark in our relationships (social dimension). Daily life in lock down seems to be a distant and now faded memory, even if a few months have passed since we were barricaded in our homes: yet certain habits have been, perhaps irrevocably, changed. It is our intention to try to identify these micro-traumas that have occurred at the level of communication practices in this last year and a half in order to be able to interpret them as traces of new possible social configurations: that is, we want to reflect on the turmoil that has occurred in daily interactions between people, between systems and between people and systems and hypothesize their possible developments on some essential aspects of social and, more specifically, communicative relationships. In particular, it is useful to focus our attention on two aspects of our daily life that have suffered an attack (almost in a chemical sense), proposing new reasons of high criticality and uncertainty to the already complex postmodern life: on the one hand (the macro-social one), the authority / credibility of the information sources, on the other hand (the micro-social one), the management of spaces and communication channels.
Processi di self-digital identity building dei protagonisti della politica locale: narrazioni social nel caso dei candidati sindaco a Napoli
Authors: Punziano Gabriella , Padricelli Giuseppe Michele
Published: January 2024

Starting from the assumption related to the personalization of politics (XXX) that open to those disintermediated ways in which build relations with the electors, this paper is focused on those identity building processes digitally held. The digital-self that politicians self-build on digital media and on the social media-sphere thanks to specific narrative frames. The case study adopted delas with the local election in Naples in October 2021. It retraces the narrations self-built by the candidates on Facebook and Twitter. The empirical work is projected to a digital-mixed content analysis (Punziano, 2022) oriented to define profiles and trajectories of the self-identity building process of candidates, the features of those identities, the configuration of the relations with the connected electors and the impacts of their communication strategies on the electoral results. In line with these objectives, we intend to comprehend if the digital self-constructions of candidates have been pushed by the same electoral event, how they were different before the candidates’ nominations and if they shut down later the electoral campaign.
Assessment of Development Intervention gaps on livelihoods of pastoralist in Selected District: The Case of West Hararge zone Selected Stakeholders
Authors: Gabusho Tamiru , Tadesa Edosa , Deneke Seifu
Published: January 2024

The study was to assess development interventions gaps on pastoralist economic development in West Hararge Zone, Ethiopia. The qualitative and quantitative data surveys were employed, and data were collected from 160 respondents. In doing, the maximum likelihood estimation of logit model was applied to identify development stakeholders, and used descriptive statistics to know how much beneficiaries were benefited from intervention. In addition, SWOT analyses were applied to the extent of stakeholder’s intervention. Finally, to develop way of recommendation to each stakeholder; the researchers were used Spearman’s rank analysis as (Charles Edward Spearman, 1863-1945) to assess the rank of stakeholders contribution. Therefore, the result of the study shows; among stakeholders of pastoralist development, the sectors rank awarded based on their participations’ contribution to pastoral development were positively follows; education sectors of government [1], productive safety net program [2], cooperative Oromia promotion; Busa Gonofa sector institution3, pastoral development government sector [4], water sector of government [5], and care Ethiopia non-government organization [6].
Creutzfeldt Jakob Disease: An Incurable Malady
Authors: Koppolu Bhavana , M Ganesh, K. , Arayamparambil Padmakumar V. , Sarada Pooja Prathapan , Chandan Garud Suresh
Published: January 2024

Creutzfeldt Jakob Disease is a rare and fatal neurodegenerative disorder characterized by rapidly worsening dementia, myoclonic jerks and akinetic mutism. It accounts for more than 90% of all human prion diseases. Over 90% of patients progress from normal function to death in under a year. There is no definitive treatment and it must be distinguished from other causes of rapidly progressive dementia such as viral encephalitis, autoimmune and paraneoplastic encephalitis which will respond to appropriate therapy. In the following 2 cases, we describe patients with presentation of rapidly progressive dementia which was finally diagnosed as Probable sporadic CJD. It is essential to make early diagnosis as it will allow patient and family to understand the course of disease and prognosis
COVID-19 Pandemic: Malaysian Undergraduate Students’ Perceptions of Online Learning
Authors: Nasir Nazatul Syima Mohd , Baharuddin Khairul Hisyam , Stark Alexander
Published: January 2024

The Covid-19 pandemic has introduced a new normal characterized by online learning. Students and instructors have been forced to familiarize with the online technologies and media that will foster learning. While many institutions and learners have embraced it, they have different perceptions of online learning depending on their experiences. The following research, therefore, seeks to research on Malaysian undergraduate students’ perception of online learning. Participants were obtained from one of the Malaysian universities. Ten participants engaged in the research and data was collected using a semi-structured interview where the participants were asked questions related to the topic. On the type of media commonly used by the leaners, all said that they preferred WhatsApp groups while 30% and 10% preferred zoom meeting and Moodle respectively. On whether the faculty had adequate resources, 70% of the participants agreed while the rest disagreed stating that they miss lessons as a result of insufficient resources. 80% of the learners also pointed out the intensity and quality of the internet as the main issue. Moreover, they were being given more assignments than course material because of the low innovation among undergraduate teachers. Half of the participants agreed that teachers had adequate resources to facilitate online learning.
The Shape of Water
Authors: Bojkowska Dorota
Published: January 2024

The quatrefoil motif, a widespread symbol in ancient Mesoamerica, is associated with caves and serves as a portal to the supernatural world, enabling communication with gods and ancestors. This article investigates the undeciphered Maya logogram T510cd, commonly referred to as the quatrefoil glyph due to its distinctive shape. Through a comprehensive analysis of inscriptions featuring T510cd, complemented by selected iconographic, archaeological, and ethnographic investigations, this article sheds new light on previous attempts to decipher the quatrefoil glyph. The study reveals that logogram T510cd likely represents the Maya word "ch’en," signifying openings or holes in the earth, often indirectly related to pools and caves.
Mauricio Amster: un polaco al servicio del libro hispano. Propuestas de interpretación
Authors: Kurek Marcin
Published: January 2024

El objetivo del artículo es evocar la figura de Mauricio Amster (1907-1980), un diseñador gráfico polaco, tipógrafo, diseñador de libros, revistas y carteles, nacido en Lviv, formado en una escuela de diseño en Berlín, quien, actuando en España y especialmente en Chile, en ambos países sentó las bases de la cultura moderna del libro. En el artículo se propone explorar la obra de Amster a través del concepto de "shifter", examinando cómo sus "libros-objetos" funcionan como signos simbólicos e indiciales que combinan arte autónomo y producción en masa, y cómo estos elementos se entrelazan en el contexto de la post-vanguardia y la sociedad de la época.
Skrining fitokimia dan uji aktivitas antioksidan ekstrak metanol daun salam (Syzygium polyanthum (Wight.) Walp.) dari Gampong Bunot, Pidie Jaya dengan metode DPPH
Authors: Nazirah Nazirah , Nasution Muhammad Amin , Ridwanto Ridwanto , Nasution Haris Munandar
Published: January 2024

Antioksidan merupakan senyawa yang mampu menunda, memperlambat atau menghambat reaksi oksidasi makanan atau obat. Antioksidan termasuk senyawa pendonor elektron yang bekerja dengan cara mendonorkan satu elektronnya kepada senyawa yang bersifat radikal bebas sehingga aktivitas radikal terhambat. Salah satu tanaman yang dapat dijadikan sebagai sumber antioksidan alami yaitu daun salam (Syzygium polyanthum (Wight.) Walp). Daun salam mengandung senyawa metabolite sekunder diantaranya alkaloid, tanin, saponin, steroid, triterpenoid, dan flavonoid yang berperan sebagai antioksidan. Tujuan penelitian adalah untuk mengetahui apakah ekstrak metanol daun salam untuk mengetahui apakah ekstrak metanol daun salam (Syzygium polyanthum (Wight.) Walp.) yang tumbuh di Gampong Bunot, Pidie Jaya mengandung metabolit sekunder dan memiliki aktivitas sebagai antioksidan.Penelitian ini dilakukan secara eksperimental, dimana sampel yang digunakan adalah daun salam. Tahapan penelitian ini meliputi pengolahan bahan tumbuhan, pembuatan ekstrak metanol daun salam, pemeriksaan karakterisasi, skrining fitokimia, dan uji aktivitas antioksidan ekstrak metanol daun salam dengan metode DPPH. Ekstrak daun salam dibuat dengan metode maserasi dengan menggunakan pelarut metanol yang diperoleh dan dipekatkan dengan rotary evaporator, selanjutnya dilakukan uji skrining fitokimia dan uji aktivitas antioksidan ekstrak metanol daun salam dengan metode DPPH (1,1 diphenyl-2-picrylhidrazil) pada panjang gelombang 516 nm dan vitamin C sebagai pembanding. Berdasarkan hasil uji skrining fitokimia terdapat perbedaan metabolite sekunder pada ekstrak metanol daun salam yang tumbuh di Gampong Bunot, Pidie Jaya antara lain alkaloid, flavonoid, saponin, tanin, steroid, dan glikosida. Dan hasil uji aktivitas antioksidan ekstrak metanol daun salam didapatkan nilai IC50 sebesar 25,68  µg/ml dan nilai IC50 Vitamin C sebesar 4, 537 µg/ml dengan kategori keduanya sangat kuat.
Abordagens Terapêuticas no Transtorno do Espectro Autista: Uma Revisão Atualizada
Authors: Fernandes Sousa Mayra Luana , Dos Santos Vieira Luisa , Azeredo Bittencourt Tavora Letícia , Contin Ferreira Oliveira Débora , Yumi Pena Ogata Rafaela , Guedes Fonseca Mariana , Dias do Nascimento Brenda , Andreoti Borges Mariani , Alves do Carmo Ana Karla , Del’ Arco Cervo Vitória , Joverno Domingues Laís , Galdino Pilatti Giovanna , Hecktheuer Canzi Ana , Gehlen Montecinos Gallo Breno Rafaelle
Published: January 2024

Esta revisão científica oferece uma abordagem abrangente e atualizada sobre as terapias aplicadas em Transtornos do Espectro Autista (TEA). Dada a natureza complexa e diversificada do TEA, torna-se imperativo analisar minuciosamente as estratégias terapêuticas disponíveis para uma compreensão mais profunda e eficaz dessa condição. O espectro autista abrange uma variedade de sintomas e desafios, e este estudo visa oferecer uma visão holística das práticas terapêuticas, desde intervenções comportamentais intensivas até modalidades farmacológicas, proporcionando assim um panorama abrangente do cenário atual.

Destaca-se não apenas a diversidade de abordagens terapêuticas disponíveis, mas também enfatiza a importância crucial da intervenção personalizada e precoce. Reconhecendo a heterogeneidade do espectro autista, a revisão salienta como estratégias terapêuticas adaptadas às características individuais dos pacientes podem ser fundamentais para maximizar os resultados. Essa personalização não apenas reconhece a singularidade de cada indivíduo, mas também destaca a necessidade de uma abordagem multifacetada e integrativa no tratamento do TEA.

Explorando as últimas descobertas e desenvolvimentos na área, este estudo não se limita a consolidar informações existentes, mas busca fomentar uma reflexão crítica sobre as práticas terapêuticas atuais em TEA. Ao fazer isso, o trabalho oferece insights valiosos para profissionais de saúde, pesquisadores e familiares, promovendo uma compreensão mais profunda das estratégias terapêuticas e, consequentemente, contribuindo para a melhoria contínua da qualidade de vida de indivíduos com TEA.
A IMPORTÂNCIA DA EQUIPE MULTIDISCIPLINAR NA REABILITAÇÃO DE PACIENTES CRÍTICOS: AVALIANDO A COLABORAÇÃO ENTRE PROFISSIONAIS DE SAÚDE NA REABILITAÇÃO DE PACIENTES DE UTI
Authors: Chagas Kamilla Victória Bastos Lima , Correia Eriselma Alves , Farinha Pablo Ryan Galvão , Rocha Talita Souza , Nascimento Graziele Coêlho , Souza Bruna Peixinho , Alves Jande Cleyson Batista , Oliveira Leila Maria Cintra da Cunha Sampaio , Romanini Rafaela Flores , Silva Bárbara Cristina Sousa da , Lima Marcos Vinicius Costa , Vicente Maria Liberdade de Oliveira
Published: January 2024

A reabilitação de pacientes críticos na Unidade de Terapia Intensiva (UTI) exige uma abordagem multidisciplinar, unindo médicos intensivistas, fisioterapeutas, enfermeiros, psicólogos, terapeutas ocupacionais e fonoaudiólogos. Essa colaboração é essencial para oferecer cuidados holísticos, indo além do tratamento médico. A coordenação liderada pelos médicos intensivistas, junto aos fisioterapeutas, enfermeiros e profissionais de saúde mental, desempenha papel crucial na mobilização precoce, preservação da função muscular e respiratória, avaliação psicossocial e reintegração do paciente. A comunicação eficaz entre esses profissionais é vital para otimizar os resultados, reduzir complicações e melhorar a qualidade de vida do paciente. Essa abordagem integrada não só melhora a experiência do paciente, mas também reduz o tempo de internação na UTI, diminui a taxa de mortalidade e promove uma recuperação mais rápida após a alta. A atuação conjunta da equipe multidisciplinar destaca a importância da abordagem holística, integrando aspectos psicológicos, espirituais e familiares. A comunicação eficiente humaniza o cuidado e evita erros hospitalares. A colaboração entre os profissionais de saúde, com foco na abordagem multidisciplinar, é crucial para proporcionar um plano de cuidados completo e de alta qualidade aos pacientes críticos na UTI, representando um avanço significativo nos serviços de saúde para esse grupo.
"Rejang Ilud, the Sacred Dance of Empowerment and Symbolism"
Authors: Suratmaja Dewa Dwi Ardi
Published: January 2024

Bali is known for having numerous centers of classical art, but since the 1970s, the artistic focal point of the island has been Gianyar Regency. The 1970s marked Bali's shift toward culture-based tourism, making tourists more aware of the rich artistic heritage in Gianyar. The sacred Rejang Ilud dance, which accompanied Hindu ceremonies, was once prevalent in this village. However, over the past 15 years, it has been supplanted by the Rejang Dewa dance, a common occurrence with Rejang dances across Bali. Rejang Ilud dance represents a synthesis of various communication elements, including movement as the dance choreography, sound and language as the accompanying music, and appearance as the makeup and costume—a reality shaped by complementary forms. The understanding of the diverse communication elements found in dance goes beyond rational comprehension; the sharpness of perception is vital in capturing the true essence. Recently recognized by the government as a National Intangible Cultural Heritage (WBTB) in 2021, the Rejang Ilud Dance in the village of Buahan, Payangan District, Gianyar, features a distinctive move called Ngilud. This motion involves the palm seemingly grasping something and moving from the inside to the outside. The presence of the ngilud movement can be associated with bodhyagiri mudr?, a hand gesture symbolizing the act of grasping. The awareness of women regarding their role can potentially impede or rectify the hastening of the era of destruction (kaliyuga). Hinduism itself teaches that the destruction of the world is significantly influenced by the Sakti community.
Challenges of Seaweed Cultivation in Nusa Penida for Economic, Tourism, and Environmental Sustainability
Authors: Putra Ida Bagus Gede Karyambara
Published: January 2024

Seaweed production in Indonesia is distributed across 23 provinces. The top five provinces in seaweed production, according to rankings, are South Sulawesi, East Nusa Tenggara, North Kalimantan, Central Sulawesi, and West Nusa Tenggara. Among the dozens of seaweed-producing provinces, Bali has the potential for seaweed cultivation, supported by a vast marine area of 95,000 km2. The Nusa Penida sub-district of Klungkung Regency, the community shows interest in becoming seaweed farmers. The accessibility for seaweed farming in Nusa Penida is due to its location approximately ten nautical miles southeast of Bali, and its coastal area is recognized as a "museum" of rare seaweed globally. Farming activities and the seaweed production process have become a mainstay for export activities, contributing significantly to Indonesia's export value. The ease of cultivation and low capital requirements are factors that determine coastal residents' choice to become seaweed farmers. However, seaweed often faces obstacles in meeting domestic and export demands. While seaweed cultivation in Nusa Penida faces challenges, the community's resilience, coupled with innovative solutions and sustainable practices, positions seaweed as a valuable and versatile marine resource with the potential to contribute to both economic development and environmental conservation in the region.
Bali to Plan Tourist Retribution in 2024
Authors: Trisnawathi Ida Ayu Adi
Published: January 2024

There are intentions to enhance Local Revenue (PAD) in Bali Province. In recent years, tourism has emerged as a vital economic sector, contributing significantly to regional income. Local governments adept at managing tourist attractions stands a better chance of increasing local original revenue (PAD). In conclusion, the proposed introduction of a mandatory levy of IDR 150,000 per person for foreign tourists visiting Bali reflects the Bali Provincial Government's commitment to addressing budget deficits and enhancing local revenue. This initiative, aligned with Law No. 15 of 2023, aims to safeguard Bali's culture, natural environment, and infrastructure development. The funds collected are intended to support environmental conservation and waste management, contributing to the sustainability of Bali's tourism sector. The Bali Regional People's Representative Council (DPRD Bali) has taken steps to ensure transparency in fund management, emphasizing the mandatory nature of the levy and outlining sanctions for non-compliance. Tourism stakeholders, including the Bali Tourism Board, generally support the imposition of levies on foreign tourists, considering it a global practice. The success of this initiative depends on the careful management of funds, collaboration among stakeholders, and adherence to regulations. If implemented successfully, the levy has the potential to generate significant revenue, estimated at around IDR 900 billion per year if foreign tourist visits reach pre-pandemic levels. The ultimate goal is to utilize these funds for the development of Bali's tourism infrastructure, targeting premium and upper-middle-class international tourists while promoting sustainable tourism practices.
Deconstructing Symbols and Meanings in the Kecak Dance
Authors: Alit Sankara
Published: January 2024

Initially, tourists visited the village where the group resided to witness the Kecak dance. However, the dance's popularity grew, and it became a feature in various events. Tourists could now enjoy Kecak performances at destinations like Uluwatu, Tanah Lot, Batubulan, and others, which provided dedicated spaces for these performances. The Kecak dance, born out of creative cultural expression, became a unique art form showcased specifically for tourists. The choreography in Kecak dance is divided into five parts. In this choreography, all elements in the Kecak performance interact, creating a message directed to the audience. In dramaturgical analysis, it's important to note that Kecak Dance focuses on the aspects of performing arts. It is a dance highly specific to Balinese culture with unique characteristics reflecting their identity and cultural heritage. In the analysis of the staging of Kecak Dance using Symbolic Interactionism Theory, it portrays human life from a Hindu perspective consisting of Suka (joy), Duka (sorrow), Lara (pain), and Pati (death). The characters in Ramayana represent the qualities of protagonists and antagonists, which then interact with each other, giving rise to new universal values, such as Loyalty. Understanding the message in Kecak dance can be enhanced by increasing the involvement of tour guides as providers of additional information to tourists. Additionally, providing brochures containing synopses of the Ramayana story or the plot of Kecak dance in foreign languages during the performance can help the audience understand the presentation more easily, allowing the art to be fully appreciated.
EXAMINING THE IMPACT OF FEMALE-CENTRIC MEDIA ON GENDER NORMS: AN ANALYSIS OF HINDI SOAP OPERAS
Authors: Sushmitha Kotian  , Dr. Vidya N
Published: January 2024

Purpose:In todays world, media plays a vital role in conveying messages and information, serving as the easiest and quickest means to reach people within a short period. Soap operas, being the oldest and most straightforward method of storytelling, effectively communicate messages to the audience. Numerous soap operas run successfully, delivering social messages and providing daily entertainment. People are inevitably influenced by soap operas, as these shows are interconnected in a manner that makes viewers feel as if the events are unfolding in their own lives. Nowadays, there is a growing trend of women-oriented soap operas that not only entertain but also convey social messages. Especially in the realm of Hindi soap operas, this underscores the crucial need to recognize their potential impact on shaping cultural perspectives regarding gender roles. This study aims to explore the impact of women-oriented soap operas on societal and mental development. These shows have the potential to influence society with new ideas and experiments, contributing to its growth and evolution over time.
Methodology / Design /Approaches: It is an exploratory study with the help of secondary data where the researchers have conducted a content analysis of various magazines, articles, google scholar, data based and related websites.
Findings and results: Soap operas portray women characters in an inspiring manner, motivating society to take on challenges and strive for achievement. According to numerous studies, women-oriented motivational soap operas have a substantial audience, and their impact on society is significant. Viewers form emotional connections with these characters, especially women who find relatability in their daily routines. Challenging traditional stereotypes is a prominent theme in contemporary soap operas, appreciated by audiences, and contributing to societal acceptance of change.
Originality/value: It is a descriptive study, exploration and analysis, which synthesizes empirical research to reveal subtle insights into the transformative potential of collective virtual environments to contribute value to developing innovative and efficient learning methods.
Type of paper: Descriptive research with exploratory research design.
KEYWORDS: Soap Opera, Media, Audience, Television, Society, Women, Motivation, Achievements, Knowledge.
EFFECT OF ENVIRONMENTAL MARKETING ON CHANGE IN MARKET SHARE: MODERATED MEDIATION OF INTERNAL GREEN MARKETING ORIENTATION AND STRATEGIC GREEN MARKETING ORIENTATION
Authors: Dr. Sukanya Metta
Published: January 2024

The study is conducted to examine the influence of environmental marketing on changes in market share. Specifically, it aims to explore the intricate functions of internal green marketing orientation and strategic green marketing orientation as possible moderated mediators. Based on the expanding domain of green marketing and sustainable business practices, this study suggests that the impact of environmental marketing on market share is contingent upon a firms internal green marketing orientation. Furthermore, the efficacy of this mediation is dependent on the firms strategic stance towards green marketing. The study applies regression modelling to examine the claimed links, using a sample of 150 enterprises across various industries. The findings suggest that organisations that possess a strong internal green marketing orientation see an upward trend in terms of market share. The aforementioned findings highlight the significance of incorporating internal and strategic green marketing strategies with environmental marketing endeavours. In order to optimise market share growth through environmental marketing, it is crucial for organisations to establish a comprehensive alignment between their internal operations and strategic green initiatives. This research provides significant insights for managers and marketers who seek to utilise environmental activities as a means to gain a competitive edge in the market. It emphasises the need of adopting a unified and internally coherent strategy to green marketing.
KEYWORDS: Environmental marketing, Internal green marketing orientation, Strategic green marketing orientation, Market share, Sustainable business practices, Competitive advantage
THE ROLE OF EMOTIONAL INTELLIGENCE AS MODERATION BETWEEN THE INFLUENCE OF FORENSIC ACCOUNTING AND INVESTIGATION AUDIT ON BEHAVIOR OF CORRUPTION
Authors: Rusli Yohanes
Published: January 2024

This study aims to examine the effect of forensic accounting on corrupt behavior and the influence of investigative audits on corrupt behavior. The Role of Emotional Intelligence as a moderator between the Influence of Forensic Accounting on Corrupt Behavior. The role of Emotional Intelligence as a moderator between the influence of Audit Investigation on Corrupt Behavior. By using multiple regression analysis. The researcher concludes that there is an effect of Forensic Accounting and Investigative Audit on Corrupt Behavior and the role of Emotional Intelligence as a moderator between the influence of Forensic Accounting and Investigative Audit on Corrupt Behavior
THE IMPACT OF CLAIM EXPENSES, UNDERWRITING RISK, PROFITABILITY, COMPANY SIZE AND RETENTION RATIO ON SOLVENCY OF INSURANCE INDUSTRY
Authors: Sutanto Shelby , Lesmana, S.Kom, MM Iwan , Sitardja Meco
Published: January 2024

The main purpose of this research is to analyze Claim Expenses, Underwriting Risk, Profitability, Company Size, and Retention Ratio on Solvency of Insurance Industry. The purpose of this research is to help future investors in choosing the right insurance company. This research was a quantitative descriptive research method. The sample used in this research is secondary data of Insurance Industry on the period from 2015 to 2020. Using SPSS (statistical package for the social sciences), methods of analysis used in this study include tolerance and VIF test, Kolmogorov-Smirnov test, multivariate cointegration tests: Test, SRESID and ZPRED estimation, t-statistical tests, F-statistical test, coefficient of determination (R²), and Pearson Correlation Product Moment. The result of this research shows claim expense, underwriting risk, ROA, and company size have significant influence on insurance industry’s solvency, but retention ratio has no significant influence on insurance industry’s solvency. All the independent variables simultaneously from a good model to explain the solvency since the magnitude of the effect value is 83,4%, while remaining 16,6% is explained by other variables besides claim expense, underwriting risk, ROA, company size, and retention ratio. The linear regression produced a formula to calculate the solvency, so this formula could be used in monitoring the financial health of an insurance company.