bluuebunny/crossref_metadata_2025 huggingface dataset:
Experimental Analysis of Mechanical Properties on Hybrid metal Matrix Composite (AA7175/ B4C/SiC)
Authors: Kumar Neeraj Kumar Neeraj , Khanduja Dinesh Khanduja Dinesh , Singh Ravi Pratap Singh Ravi Pratap
Published: April 2023

Hybrid composites are far more superior to existing conventional composites. Among hybrid composites, hybrid aluminum based metal matrix composite plays a pivotal role in the present time. HAMCs have key properties such as less weight-to-strength ratio, high wear & temperature resistance, high hardness, good stiffness, etc. which makes them extremely important in advanced industrial applications, especially in modern sectors such as Automotive, Aerospace, Defense etc. The demand for HAMCs is steeply rising so a thorough understanding of HAMCs becomes important. In this research, AA7175 has been used with SiC, B4C & Graphite as reinforcements in different amounts (3, 6, 9, 12 respectively) of weight percent. Mechanical properties of HAMCs i.e., hardness, tensile strength & percentage elongation have been analyzed. Experimental results show that tensile strength and hardness increase with the increment of reinforcement quantity but percentage elongation decreases. The hardness and tensile strength improved up to 12% of weight of SiC, B4C, and Graphite particles. Few experiments have been done using AA7175/SiC, B4C, and Gr because of which this archive study is unique. This study's methodology could be very helpful for producing high-strength components utilizing Stir Casting, which is a relatively inexpensive casting technique.
Petrographic Characterization and Diagenetic Impact on Bhuban Sandstones of Surma Group, Aizawl, Mizoram
Authors: Bawri Gautam Raj , Vanthangliana V. , Srinivasa K. , Mahanta S. J. , Lalduhawma K. , Bharali Bubul
Published: April 2023

A comprehensive study based on petrographic analyses of Bhuban sandstones belonging to the Surma Group have been carried out in order to determine the various aspects such as depositional environment, tectono-provenance, textural and mineralogical properties, as well as to assess the depositional environment. The most dominant detrital framework constituents of Bhuban sandstone are Quartz (average 83.59%), which is followed by Feldspars (average 7.94%), and Lithic fragments (average 8.47%), matrix, cement, secondary and accessory minerals. The Bhuban sandstone samples are classified as sublith arenite to subarkosic varieties, tightly packed and are characterized by fine to medium-grained with poor to moderately sorted grains. The provenance discrimination diagrams depict the derivation of the detrital framework grains mostly from the upper and middle ranks of metamorphic rocks. The studied sediments were derived from recycled orogen as well as from quartzose recycled, which are marking a composite provenance in humid climate conditions. The study reveals that the area has undergone three distinct diagenetic stages. The Bhuban sandstones have been impacted by several diagenetic processes, which include compaction, cementation, mineral overgrowth, grain fracturing, albitization, recrystallization, replacement, and dissolution of minerals grains. These diagenetic processes that affected the studied samples underwent three different stages of diagenesis, which include early, late, and uplift-related stages. Cementation, minerals replacement, authigenic minerals, quartz and feldspars overgrowth, mechanical compaction, muscovitization, chloritization, concave-convex-suture contacts, recrystallization, albitization, etc. are present which indicates the early to late diagenetic stages of the examined Bhuban sandstones, whereas mechanical compaction, alteration & dissolution of framework grains, precipitation of authigenic minerals and cementation that leads to the decrease the porosity and permeability of the Bhuban sandstones.
Association of atopic dermatitis with schizophrenia and schizoaffective disorder: A case-control study in the All of Us Research Program
Authors: Fan Ryan , Chen Gloria , Leasure Audrey C. , Johnson Matthew C. , Damsky William , Cohen Jeffrey M.
Published: April 2023

Atopic dermatitis (AD) has been previously associated with mental health comorbidities, but studies investigating the relationship between AD and schizophrenia and schizoaffective disorder have been limited. Using electronic health record data from the National Institutes of Health All of Us Research Program (AoURP), we conducted a case-control study comparing rates of schizophrenia and schizoaffective disorder among patients with AD and matched controls. Among 240,635 participants, we identified 13,433 AD cases and 53,732 controls matched to age, sex, and race/ethnicity. When compared to controls, patients with AD were more likely to have a diagnosis of schizophrenia (2.0% vs. 1.1%, P < 0.001) or schizoaffective disorder (1.8% vs. 0.5%, P < 0.001). AD remained significantly associated with schizophrenia (OR 1.64, 95% CI 1.39–1.93) and schizoaffective disorder (OR 2.44, 95% CI 2.01–2.97) in multivariable analyses that adjusted for age, sex, race/ethnicity, income, smoking status, major depressive disorder, and generalized anxiety disorder. Further study is warranted to better understand the pathophysiologic mechanisms behind the relationship between AD and schizophrenia and schizoaffective disorder.
Metabolic Syndrome and Hypovitaminosis D in Children and Adolescents: A Systematic Review
Authors: Martins Gabriele Soares , Silva Isabelle Oliveira Santos da , Santos Gabriele Paiva , Melo Paulo Roberto Santana , Menezes Carlos Alberto
Published: April 2023

Determine the correlation between metabolic syndrome and hypovitaminosis D in children and adolescents.
Data source: systematic review of the literature, PROSPERO registry: CRD42022353545, performed through the evaluation of studies indexed between 2012 and 2022, in the PubMed, ScienceDirect and Web of Science databases. Texts in English and Portuguese were searched for by the DeCS/MeSH descriptors “Metabolic Syndrome” AND “Vitamin D Deficiency” AND Child AND Adolescent. 163 articles were found. After analysis and application of the eligibility criteria, 30 articles were selected.
Data synthesis: 28 were observational and 2 were randomized clinical trials. The samples ranged from 29 to 6589 children and adolescents and the age group between 3 and 18 years. A direct relationship between metabolic syndrome and hypovitaminosis D in pediatrics was identified in 15 studies. Regarding the components of the syndrome, 14 articles highlighted obesity, with a higher frequency of vitamin D deficiency or insufficiency in obese children and adolescents. In addition, 10 articles observed an inverse relationship between 25(OH)D levels and glycemic levels. Finally, vitamin D supplementation was associated with improvement in syndrome parameters.
Conclusions: Thus, the relationship between metabolic syndrome and hypovitaminosis D in pediatrics is evident. Preventive measures are necessary in order to prevent early and future cardiometabolic complications.
Real-world treatment outcomes of carfilzomib plus dexamethasone in patients with relapsed and/or refractory multiple myeloma, focusing on the impact of trial-fitness: Catholic Research Network for Multiple Myeloma Study (CARE-MM 2203)
Authors: Park Sungsoo , Goo Seoyoung , Jeon Youngwoo , Yhang Seungah , Shin Seunghwan , Min Changki
Published: April 2023

Introduction
Carfilzomib plus dexamethasone (Kd) is widely used in patients with relapsed and/or refractory multiple myeloma (RRMM). However, the treatment outcomes of Kd, especially in trial-unfit patients, have not been extensively studied in the real-world setting.
Methods
We analyzed the outcomes of 152 RRMM patients who received Kd at our hospitals from April 2018 to March 2022.
Results
At the commencement of Kd, they received a median of two (range, 1–7) lines of prior anti-myeloma therapy. According to the ENDEAVOR study criteria, 93 (61.2%) and 59 (38.8%) patients were classified as the trial-fit and the trial-unfit group, respectively. The overall response (OR) rate for the entire cohort was 71.1% (95% CI: 63.2%-78.1%). Median time-to-next treatment (TTNT) and overall survival (OS) were 8.0 months (95% CI: 6.8–10.8 months) and 22.8 months (95% CI: 13.4–38.0 months), respectively. There was no significant difference in the OR rate between the trial-fit and the trial-unfit groups (76.3% vs. 62.7%; P = 0.105). However, the median TTNT (5.8 vs. 10.3 months; P < 0.001) and OS (15.0 vs. 36.8 months; P = 0.009) were significantly shorter in the trial-unfit group. On multivariate analysis, trial-fitness (unfit vs. fit) remained a significant covariate affecting the TTNT (HR: 1.65, 95% CI: 1.14–2.40; P < 0.001).
Conclusion
Our data suggest that the treatment outcomes of Kd are acceptable in the real-world setting, with significant differences between the trial-fit and the trial-unfit groups, although they are relatively inferior to those of a pivotal trial.
Primary Pleural Hydatidosis Presenting as an Isolated Cough: A Rare Case Report
Authors: George Marlyn Susan , Jagannath Preethi , Byuzandyan Tigran , Baghumyan Natalie , Khanoyan Armen , Hashmi Md Foorquan
Published: April 2023

Background
Hydatid disease is caused by Echinococcus granulosus organisms. The liver is the most affected organ followed by the lungs. The pleural cavity being the primary location of hydatid cysts is rare and should be discussed further. This paper documents a rare case of primary pleural hydatidosis which can present with a mere isolated cough followed by dyspnea. The diagnosis and surgical treatment along with post-operative medications are vital in this case.
Case presentation
We present a case of a 45-year-old who suffered from a cough for one week which did not subside after taking medications. This symptom was followed by dyspnea for which an X-ray was done which showed left-sided pleuraleffusion, a complication of pleural hydatidosis. Computed tomography was performed to confirm the diagnosis of primarypleural hydatidosis. It revealed multiple cysts in the pleural cavity without them being present at other sites. Blood work revealed eosinophilia which is significant in parasitic diseases. A left posterolateral thoracotomy was performed and the cysts were surgically removed. Additionally, empyemectomy and pleurectomy were done. The patient was then treated with anti-parasitic therapy and was advised to get X-rays during the follow-up visits. The X-rays were normal and indicated that there was no disease recurrence.
Conclusion
This case implies the significance of a cough of more than a week that is not relieved by medications. This should be carefully evaluated and followed in cases that have a rare diagnosis requiring surgery. A diagnosis of primary pleural hydatidosis with left-sided pleural effusion and atelectasis with mediastinal shift to the right side was made which was treated with a surgical procedure.
Prevalence and associated factors with adverse birth outcome among women who gave birth at Debre Markos General Hospital, East Gojjam Zone, Ethiopia, 2022: A cross-sectional study
Authors: Dagnaw Yilkal
Published: April 2023

Background
Adverse birth outcomes are a common public health problem in the developing world, including Ethiopia, and it is important for planning maternal and child health care services. There are several indices of adverse birth outcomes, such as stillbirth, preterm birth, low birth weight, small for gestational age and congenital anomalies.
Objective
This study aimed to determine the prevalence and associated factors of adverse birth outcomes among women who gave birth at Debre Markos General Hospital.
Methods
A health facility-based cross-sectional study was conducted from July 1 to August 1/2022 on laboring women who attended Debre Markos General Hospital. A total of 337 study participants were selected using a systematic sampling method. Data were collected through interviews with a structured questionnaire. Epi Data version 3.1 was used for data entry, and it was checked for completeness, cleared and analysed using Statical Package for Social Sciences software. Bivariable and multivariable logistic regression analyses were employed; a P value of less than 0.05 was considered a statistically significant factor for discontinuation.
Result
- The overall proportion of this study showed that 88 (26.1%) women had adverse birth outcomes, including 26 (7.7%) stillbirths and 31 (9.2%) preterm and low birth weights. Rural residence, no antenatal care, antepartum haemorrhage, pregnancy-induced hypertension, illiteracy, post term pregnancy, birth interval less than two years, and age less than 20 years were independently associated with adverse birth outcomes.
Conclusion
- In this study, the overall proportion of adverse birth outcomes was low compared to previous studies. Residence, no antenatal care follow-up, antepartum haemorrhage, pregnancy-induced hypertension, post term pregnancy, birth interval less than two years, educational status (illiteracy), and age less than 20 years were associated with adverse birth outcomes. Therefore, increasing accessibility and improving awareness in rural communities to seek antenatal care as well as encouraging women's education to higher education levels is vital to improve good birth outcomes.
Value-for-Money Drivers in Public-Private Partnerships in Affordable Housing in Indonesia: An Analytic Network Process Perspective
Authors:   Center of Excellence in Urban Infrastructure Development and Department of Civil Engineering, Parahyangan Catholic University, 40141 West Java, INDONESIA, Wibowo Andreas , Hartiati Dewi ,   Housing and Human Settlement Office of West Java Province, 10150 Jakarta, INDONESIA
Published: April 2023

This study aimed to identify the factors expected to drive value-for-money (VfM) when using public-private partnerships (PPPs) for affordable housing in Indonesia. Utilising economy, efficiency and effectiveness as the VfM criteria, the study employed the analytic network process to determine the relative importance of 13 factors compiled from the literature review. The factors were then grouped into five clusters: private sector capacity, transparent and competitive procurement, risk and reward allocation, public sector capacity and the nature of the long-term contract. The data were gathered through a survey of 20 experts with hands-on experience in Indonesia’s PPPs. Effectiveness was identified as the most critical VfM criterion, implying that bringing other VfM aspects into public decisions is indefensible if the outcome, providing low-income customers with suitable housing at rents they can afford, is not achieved. The justified scope and size of the project, clear output-based specifications, quality project planning and preparation and long-term service delivery emerged as the most critical factors enhancing VfM, each with a different focus on a specific VfM criterion based on local weights. At the cluster level, risk and reward allocation ranked the highest. This study also acknowledges several limitations and provides directions for future research.
Critical Factors Contributing to Budget Overruns in Ghana’s Telecommunication Industry Construction Projects
Authors:   Department of Operations Management, University of South Africa, Pretoria, SOUTH AFRICA, Asiedu Ernest Marfo , Mkansi Marcia ,   Department of Operations Management, University of South Africa, Pretoria, SOUTH AFRICA
Published: April 2023

This study sought to examine the occurrence of and the most critical factors that cause budget overruns in Ghana’s telecommunications industry construction projects by applying an exploratory sequential mixed method approach. A multiple case study approach was initially adopted to ensure a greater understanding of the differences and similarities between four cases drawn from companies engaged in the construction of network expansion projects. This was followed by a survey of 230 practitioners responsible for managing construction projects within the industry. The software program, ATLAS.ti, Statistical Package for the Social Sciences (SPSS) and AMOS version 25.0 were used in the data analysis. Exploratory factor analysis and structural equation modelling were performed to test and validate the hypothetical model developed to illustrate the most critical factors that cause budget overruns. The findings resulted in the final model dubbed “Budget Overrun Flowerpot”, which provides practitioners with a better understanding of the most critical causal factors that must be managed appropriately to improve project efficiency and budget performance.
Development and Single-Lab Validation of an UHPLC-APCI-MS/MS Method for Vitamin K1 in Infant Formulas and Other Nutritional Formulas
Authors: Lee Sookwang , Morris Yolanda J. , Gross Lois K. , Porter Eural E. , Ortiz-Colon Freddy , Farrow James M. , Waqar Anjum S. , Phifer Edwin C. , Kerdahi Khalil F.
Published: April 2023

Accurate analysis of vitamins is essential to help the public maintain adequate intakes of vitamins. Currently in Atlanta Center for Nutrient Analysis (ACNA), AOAC Method 999.15 with fluorescence detection is utilized for the analysis of vitamin K in infant formulas, dietary supplements and other medical foods. An UHPLC-(+)-APCI-MS/MS method for vitamin K1 (phylloquinone) was developed to improve the accuracy, selectivity and eciency of the analysis. SRM1849a and infant formula samples were used to demonstrate that vitamin K1 data by LC-MS/MS analysis matched well with those from the AOAC Method 999.15. A single-laboratory validation of an UHPLC-MS/MS method for vitamin K1 analysis in SRM1849a showed good accuracy with a mean value of 99.6% of the certified value (n = 8). Recoveries of vitamin K1 at two dierent spike levels were 99.6 and 103.7% from SRM1849a. Mean recovery of vitamin K1 from four dierent infant formula samples was 102.4% ranging from 95.6 to 115.5% with %RSD of 7.8 15.6. Precision, measured as repeatability (%RSDr), was 8.7 for SRM1849a and ranged from 3.7 to 13.4 for four infant formula samples. Application of this method will help ACNA facilitate the accurate analysis of vitamin K in infant formulas and other samples.https://doi.org/10.21423/jrs-v03n02p027 (DOI assigned 8/7/2019)
Taking and Testing GOODSamples: A Systematic Approach for Representative Sampling from Field to Test Portion
Authors: Thiex Nancy J. , Ramsey Charles A.
Published: April 2023

The following manuscript provides a brief introduction to a systematic approach for representative sampling from field to test portionSampling from field to test portion is a single measurement processError is introduced during each mass reduction stageError propagates as the square root of the sum of squares, so the largest error components have a proportionately greater impactA representative sample must be correct (unbiased) and have suciently small imprecisionThe systematic approach for developing a sampling protocol is based on two key inputs: sample quality criteria (SQC) and material propertiesThis approach requires knowledge of the total error in the measurement process (global estimation error or GEE), from primary sampling through final measurementError is estimated through quality control eventsIf the GEE meets the requirements of the SQC, a confident inference can be madeGOODSamples can be a valuable tool for the forage and feed communities to evaluate current practices and to develop new protocolshttps://doi.org/10.21423/jrs-v04n02p001 (DOI assigned 7/3/2019)
Emerging Growth of Orphan Drugs for Neurological Diseases in Japan: Potential Benefits for Both Patients and Pharmaceutical Companies
Authors: Shibata Shoyo , Kawaguchi Hitomi , Uemura Ryotaro , Suzuki Takeshi
Published: April 2023

Despite the existence of numerous rare neurological diseases, no studies have been conducted on orphan drugs for neurological diseases available on the Japanese pharmaceutical market and their potential benefits. In this context, from a statistical perspective, we investigated 1) the market position of orphan drugs in Japan, and 2) the market penetration of generic medicines. To the best of our knowledge, this is the first empirical study to examine the current status and development strategy of orphan drugs approved for neurological diseases in the Japanese pharmaceutical market. The perspectives provided by this research are expected to promote the clinical development of orphan drugs in Japan for patients suffering from intractable neurological diseases that currently have no known effective therapies. The dataset used in this research was generated from publicly and commercially available data sources in Japan. Marketing approvals for orphan neurological products have increased dramatically in recent years. As much as 10% of all drugs approved for neurological diseases in Japan were orphan drugs that met urgent medical needs. Six of these orphan drugs were ranked in top 500 best-selling drugs in Japan, which indicated the presence of a potentially large market. Compared with more conventional drugs, the prices of orphan drugs are not expected to be reduced. In addition, due to an apparent lack of competition from generics, the quantity of available orphan drugs has remained steady, suggesting stable long-term sales. Most orphan drugs in Japan have adopted innovative marketing strategies that divide major neurological diseases into a more specific variety of rare disease categories. We found that orphan drugs approved for neurological diseases in Japan have been launched steadily. It is unlikely that these drugs will be affected by regular price revisions and the launch of their generic counterparts. Based on these findings, the further development of orphan drugs in Japan should be encouraged in order to meet urgent medical needs and deliver innovative drugs to patients suffering from rare neurological diseases.https://doi.org/10.21423/jrs-v04n03p007 (DOI assigned 5/31/2019)
Development of a model of atmospheric aerothermodynamics for the study of dusting processes at tailings dumps using COMSOL software
Authors: Amosov P. V. , Baklanov A. A.
Published: April 2023

An overview of studies of aerothermodynamics and atmospheric pollution at mining facilities using computational fluid dynamics software systems (CFD modeling) has been presented. Both specialized and non-specialized software are marked. The review focuses on the studies performed using the FLOWVISION, ANSYS FLUENT and COMSOL software codes. An aerothermodynamic model of the atmosphere is described in which the equations of dynamics in the incompressible fluid approximation are supplemented by the heat transfer equation and the parameters of Coriolis, convection (buoyancy), background stratification and radiation flux. The necessary modifications in the COMSOL software are described, which make it possible to carry out studies of atmospheric aerothermodynamics under various atmospheric conditions. A two-dimensional CFD model of the atmosphere has been built and tested on a simplified representation of the tailings dump. At a fixed wind flow velocity of 5 m/s and variations in the background stratification parameter (from –0.05 to +0.05 °C/m), numerical experiments have been performed and the calculation results have been analyzed. Differences in the aerodynamic parameters of the flows and the spatial distribution of temperature under different atmospheric conditions are noted. Estimates of the dynamic velocity at the dusting height and the vertical mass flux using the empirical dependence of the dusting intensity are performed. The analytical dependence of the vertical mass flux as a function of the stratification parameter is discussed. The asymmetry (relative to the neutral state of the atmosphere) of the magnitude of the vertical mass flux in comparison with the unstable and inversion states is shown. In stable atmospheric conditions, the magnitude of the vertical flux of the dust mass, and hence the pollution of the atmosphere downstream, will be noticeably higher than in unstable states.
Mal'javr – the first gold prospect in the Archean conglomerates, the Kola region
Authors: Kalinin A. A. , Kudryashov N. M. , Savchenko Ye. E.
Published: April 2023

A new type of prospects of gold mineralization in the Kola region is considered in the paper. The Mal'javr prospect is located in the south-western flank of the Uragubsky greenstone belt in biotite gneiss – the metamorphosed sedimentary rocks with interlayering of polymictic conglomerate, gravelite, and sandstone. Gold-bearing sulfide mineralization was found in altered rocks, which form a series of lens-shaped bodies, concentrated along a shear zone of NNE strike. The bodies of altered rocks are zonal: the central zone makes 50–80 % of the lens volume, it consists of garnet and quartz, the intermediate zone is of garnet-biotite mineral composition, and in the outer zone, which is often reduced, the main minerals are hedenbergite, hornblende, and grunerite. The metasomatic alteration is connected with an increase of iron content, decrease of Al, Si, and alkaline metals Na and K, redistribution of calcium to the outer zone of metasomatic lenses; and magnesium is inert. If compared to the unaltered gneiss, the altered rocks are depleted in Rb, Cs, Sr, Ba, Zr, Nb; and content of Cu, Zn, Mn, As, Ag, Te, W, Bi (all these elements are known to associate with gold) increases. All zones of altered rocks are rich in sulfide mineralization. Pyrrhotite and arsenopyrite are the main sulfide minerals, minor minerals are chalcopyrite, pentlandite, magnetite, tochilinite, native gold, and late pyrite and marcasite. Rock alteration and formation of sulfide mineralization happened at a high temperature > 600 °С, and the late alteration processes at ~400 °C. The arsenopyrite-gold mineralization probably formed with As and Au mobilized from the host biotite gneiss during regional metamorphism or due to pegmatite vein intrusion.
Institutional Blendscapes: The Suburban Governance Role of the Diputación de Barcelona
Authors: Pagliarin Sofia
Published: April 2023

The analysis of suburbanization patterns and processes necessarily implies looking beyond towns and cities. Suburbanization is a blendscape because it occurs within the transition zone between urban and rural areas surrounding urban centres. Therefore, a tension emerges between the
growth expectations of small- and medium-sized municipalities and the supra-local authorities (e.g. metropolitan, provincial or regional public bodies) that provide essential (mostly financial) support to those municipalities. Supra-local authorities hence perform the governance role of institutional
blendscapes because they can mediate between those growth expectations and more efficient, area-wide land management. By using the Barcelona Province as a case study, this paper examines three inter-related issues in suburbanization processes: (i) the question of land transformation; (ii)
the relation between municipal size and suburban pa erns; and (iii) the role of supra-local authorities in the management of suburban areas in the city outskirts. Findings show that, overall, while municipalities up to 9,999 inhabitants have a housing stock that is predominantly suburban in
character (i.e. 76.5 per cent single-family dwellings), it is small-/mid-sized municipalities between 10,000 and 49,999 inhabitants that have the highest proportion (31.2 per cent) of suburban residential areas within the Barcelona province. These small- and mid-sized, often rural, municipalities
tend to rely on financial and technical support from the supra-local authority of the Barcelona Diputación – a key governance actor in suburbanization processes. As an institutional blendscape, on the one hand, the Barcelona Diputación can steer a more efficient land allocation
and management through environmental protection and assistance in developing (supra-)local spatial plans. On the other hand, by distributing essential financial help to provide basic public services in small- and mid-size suburban municipalities, it also partially mitigates the planning, construction,
and maintenance of suburbanity in (very) small- and medium-size municipalities 'far from the city' and rural areas.
Analysis of competition and the level of dominance in the antidiabetics market of Russia
Authors: Markov N. I.
Published: April 2023

Introduction. Amid reports of a growing number of diabetic patients, the antidiabetics market players positioning is highly important for companies and the country’s leadership. The regulatory measures and management decisions depend on the competitive situation in the market. Aim. Analysis of the changes in the level of dominance on the markets for antidiabetics and blood glucose monitors and meters. Materials and methods. The distribution of these markets by product groups, as well as by commercial and public procurement segments has been taken into account. The Herfindahl-Hirschman and Linda indices, the adjusted Hall-Tideman index, concentration ratios and the SV matrix (strength/variety) were used as analysis tools, and the calculations were made on the basis of IQVIA data for the period from 2004 to the 3rd quarter of 2022. Results. The dominance of three foreign companies that fell into the B4 and G quadrants was detected in the insulin and insulin analogues market. The glucose-lowering drugs market is the most competitive, it fell into the RO quadrant more often than other markets, and the dominant group, depending on the segment, included foreign and domestic companies with different frequency. The dominance of both three foreign and one Russian companies in the B4 and G quadrants, as well as a larger number of companies, was identified in the market for other alimentary tract and metabolism products. Several foreign and one Russian company that were identified into the B4 and G quadrants steadily dominated in the markets for blood glucose test strips, glucose monitors and meters and accessories, and lancets. Conclusions. The antidiabetics market is highly concentrated in its segments. The results show the historical development of the studied markets, the role of the commercial and public procurement segments in them, and serve as the foundation for studying the impact of environmental events on the Russian antidiabetics market.
Modeling probabilistic-based reliability assessment of gridded rainfall thresholds for shallow landslide occurrence due to the uncertainty of rainfall in time and space
Authors: Wang Xi-Jun , Wu Shiang-Jen , Tsai Tung-Lin , Yen Keh-Chia
Published: April 2023

This study aims to model a probabilistic-based reliability assessment of the gridded rainfall thresholds for shallow landslide occurrence (RA_GRTE_LS) to quantify the effect of the uncertainty of rainfall in time and space on the rainfall thresholds under consideration of local soil properties. The proposed RA_GRTE_LS model is developed by coupling the uncertainty analysis with the logistic regression equation using a significant number of the landslide-derived rainfall thresholds of the specific warning times. The 30 historical gridded hourly rainstorms at 10 study grids in the study area (Jhuokou River watershed) are used in 1,000 simulations of rainfall-induced shallow landslides under an assumption of the soil layer of 310 cm. The results reveal that the shallow landslide in the study area probably occurs at the time step of less than the 36th hour around the bottom of the soil layer (about 275 cm) during a rainstorm; also, using the proposed RA_GRTE_LS model, the resulting rainfall thresholds and quantified reliabilities, especially for the warning time of less than 18 h, exhibit a sizeable varying trend in space due to the variations in rainfall and soil properties; accordingly, the short-term rainfall thresholds for shallow landslide occurrence could be locally determined under acceptable reliability.
Evaluation of the toxicity of textile effluent treated by electrocoagulation
Authors: Martins Jéssica Elen Costa Alexandre , Abdala Neto Eliezer Fares , Ribeiro Jefferson Pereira , Lima Ari Clecius Alves de , de Souza Francisco Wagner , de Oliveira André Gadelha , Vidal Carla Bastos , do Nascimento Ronaldo Ferreira
Published: April 2023

Textile effluents are complex, making it difficult to choose an effective treatment. The textile effluent toxicity in Lactuca sativa after pulsed current (PC) electrocoagulation (EC) was evaluated in this study. The EC was performed using 304 stainless steel electrodes in batch mode. Parameters monitored included pH, temperature, color, and turbidity. Additionally, the process residue was subjected to energy-dispersive X-ray fluorescence (XFR) to determine the elements present. The process achieved proportional color and turbidity removal ranging from 97 to 99% and from 74 to 85%, respectively. Chemical oxygen demand (COD) and total nitrogen removal were 81 and 49%, respectively, in a 50 min time-lapse. The process generated approximately 1.7 kg of solid residue/m3 treated effluent. The XFR results revealed the presence, mainly, of Fe, Cr, and Ni ions in the residue, as well as chlorine. The germination index (GI) and relative growth values showed that EC reduced effluent toxicity slightly, indicating the need for complementary treatment.
Catalytic ozonation of N-methyldiethanolamine over mixed oxides derived from Mg/Fe-LDH
Authors: Boucenna Nabil , Mokhtari-Belkhadem Fatiha , Bouteiba Ali , Sahel Karima , Medina Francisco , Lounis Mourad
Published: April 2023

The aim of this study was to evaluate the efficiency of catalytic ozonation to increase the degradation of aqueous N-methyldiethanolamine (MDEA) solutions, using two lamellar double hydroxides, namely MgxFe-LDH with x = Mg/Fe = 2, 3, were synthesized by the simple and rapid co-precipitation method. Then, the obtained materials were calcined at 400 °C for 6 h. The calcined products were respectively designated as HTcMg2Fe and HTcMg3Fe, and characterized by powder X-ray diffraction (XRD), N2 physisorption (BET), Fourier transform infrared spectra (FT-IR), and scanning electron microscopy (SEM). The powders produced were used in the ozonation reaction to remove MDEA from aqueous solutions. Experimental results showed that the highest MDEA removal efficiency is in the catalytic ozonation process. Under the optimal conditions for heterogeneous catalytic ozonation of MDEA: initial concentration of 4 Wt% MDEA, 30 °C, catalyst mass of 30 mg/100 ml solution, and contact time of 60 min. The results showed the highest percentage of COD removal, which was up to 80.76% for HTcMg2Fe higher than that of HTcMg3Fe 80.36%.
Реализация теории поэтапного формирования умственных действий в формате дистанционной лекции
Authors: Пронина Анжелика Н. , Будякова Татьяна П.
Published: April 2023

Введение. В статье рассматриваются методологические и концептуальные вопросы реализации теории поэтапного формирования умственных действий П. Я. Гальперина в условиях дистанционного образования в высшем учебном заведении. Нами впервые проанализирован потенциал теории поэтапного формирования умственных действий П. Я. Гальперина для методического обеспечения дистанционных университетских лекций, описаны векторы ее трансформации в связи с электронным форматом обучения. Методы. Материалом изучения стали лекционные занятия, проводимые на платформе «YouTube». Участниками исследования выступили студенты Елецкого государственного университета имени И. А. Бунина и преподаватели, читавшие им поточные лекции с помощью сервиса «YouTube». В качестве инструмента исследования использовался метод активного интервью со студентами и преподавателями. Обработка результатов осуществлялась с помощью содержательного контент-анализа. Результаты. Было установлено, что и преимущества, и недостатки дистанционных лекций отражают психологию усвоения умственных действий, описанную в теории П. Я. Гальперина. Так, для соответствия стандартам качества образования, содержание образовательного контента, представленного в лекции, должно отвечать требованиям третьего типа обучения по П. Я. Гальперину. Должны быть обеспечены обобщенность и полнота учебного материала при соблюдении условия не превышения объема учебного материала по сравнению с традиционной лекцией. Обсуждение результатов. Полученные результаты свидетельствует о том, что дистанционная форма обучения не исключает успешного применения основных положений теории поэтапного формирования умственных действий, что еще раз доказывает важность данной теории для построения технологий успешного обучения вне зависимости от формата обучения. В контексте развития данной теории высказано мнение о необходимости обучения студентов технике обработки письменной формы дистанционной лекции, переводу ее в формат мини-конспекта.
Детско-родительские отношения и индивидуальный опыт как структурные детерминанты виктимизации в юношеском возрасте
Authors: Андронникова Ольга О. , Перевозкина Юлия М. , Леонова Олеся И.
Published: April 2023

Введение. В научной литературе представлено недостаточно исследований, определяющих специфику детерминант конкретного типа виктимного поведения. Цель исследования заключается в изучении структурной детерминации детско-родительскими отношениями и индивидуальным опытом предрасположенности и реализации различных форм виктимного поведения в юношеском возрасте. Нами впервые проанализировано объединение социальных факторов, представляющее целостный синтез, который напрямую обеспечивает реализацию форм виктимности в период юности. Методы. В исследовании (общее число респондентов – 340) приняли участие молодые люди в возрасте от 16 до 18 лет, из которых 191 девушка и 149 юношей. В исследовании использовались методики «Биографический опросник» (BIV) (Bottscher, Jager & Lischer в адаптации В. А. Чикер), «Детско-родительские отношения подростков» (ДРОП) (П. Трояновская), «Методика исследования склонности к виктимному поведению» (О. О. Андронникова). Для обработки и анализа данных были использованы критерий хи-квадрат Пирсона и множественный регрессионный анализ (пошаговая регрессия). Проведенный регрессионный анализ свидетельствует о прогностическом влиянии моделей детско-родительских отношений и социальных факторов на параметры, отражающие склонность к виктимному поведению у юношей (p < 0,000). Результаты. Выявлена специфика структурных детерминант (детско-родительские отношения, опыт негативных детских переживаний) виктимного поведения разного типа. Анализ регрессионных моделей позволяет сделать вывод о прогностическом влиянии социальных факторов на возникновение склонности к конкретным типам виктимного поведения с учетом вклада каждого фактора в общую систему детерминант. Обсуждение результатов.  Использование полисистемного принципа позволило выявить взаимное структурное влияние социальных факторов, превосходящее их простую совокупность, на склонность к реализации конкретных форм виктимности.
Измерение конспиративистской ментальности: первичная психометрическая проверка диагностической методики
Authors: Пищик Влада И.
Published: April 2023

Введение. Изучение специфики распространенности веры в различные заговоры является актуальной проблемой кризисной современности. Имеющиеся методики преимущественно центрированы на видах веры в заговоры, однако мало представлен целостный подход.  Нами впервые на российской выборке проведена разработка нового валидного и надежного инструментария для выявления особенностей конспиративистской ментальности современной молодежи. Целью данной статьи является проведение апробации и первичной психометрической проверки авторской методики «Измерение конспиративистской ментальности». Методы. Конструкт методики построен на основе этапов восприятия веры в заговоры и выделения значимых установок – устойчивости к заговорам, готовности принимать заговоры на веру, стремления искать причины заговоров и оценивать последствия и результаты их влияния на жизнь. Методический инструментарий представлен авторской методикой «Измерение конспиративистской ментальности», апробированной на 300 респондентах мужского и женского пола. Конструкт методики имеет двухфакторную структуру, на одном полюсе – готовность-устойчивость в отношении заговора, на другом – ищущий-результативный типы. Результаты. Психометрическая проверка методики показала, что у мужчин и женщин по-разному проявляется конспиративистская ментальность. У мужчин в большей степени выражена вера в заговоры. Готовый и результативный типы находятся ближе к зоне традиции, а устойчивый и ищущий типы в большей степени в зоне инновации. Подтверждена конструктная валидность методики, а также получен высокий показатель α-Кронбаха, что свидетельствует о внутренней согласованности методики. Обсуждение результатов. Полученные данные сочетаются с уже имеющимися исследованиями отдельных аспектов конспиративизма. Мы обнаружили подтверждение следующим идеям: полового различия конспиративистской ментальности, ее личностного своеобразия, специфики направленности, связи с тревожностью и основными страхами.  Заключение. Предварительная психометрическая проверка методики на представительной выборке демонстрирует ее надежность и валидность. Дальнейшая работа будет направлена на модификацию методики и сравнение возрастных групп.
Психологические особенности переживания студентами ограничения доступа к социальным сетям
Authors: Абакумова Ирина В. , Комерова Наталья Е. , Рягин Сергей Н.
Published: April 2023

Введение. Социальные сети являются инструментом поиска социальных контактов,  эмоциональной поддержки, средством самовыражения и самопрезентации. На фоне «кризиса достоверности», выражающегося в большом количестве непроверенной и часто противоречивой информации, весьма актуально изучать психологические особенности переживания студентами ограничения доступа к социальным сетям, таким, как Instagram* (проект Meta Platforms Inc., деятельность которой в России запрещена). Тема исследования информационного поведения в последние годы приобрела особую актуальность, что реализовалось в большом количестве как зарубежных, так и отечественных работ. Впервые предпринята попытка описать различия особенностей переживания студентами ограничения доступа к социальным сетям в зависимости от действий респондентов после ограничения доступа. Методы. В исследовании приняли участие 174 студента в возрасте от 18 до 21 года (61 юноша и 113 девушек), учащиеся 1-3 курсов ФГБОУ ВО «Донской государственный технический университет». Для реализации цели исследования использованы авторская анкета-опросник (И. В. Абакумова, Н. Е. Комерова, С. В. Рягин); опросник социально-психологической адаптации (СПА) (в адаптации А. К. Осницкого); опросник «Стратегии преодоления стрессовых ситуаций» (SACS) (С. Хобфолл в адаптации Н. Е. Водопьяновой, Е. С. Старченковой). Математическими методами выступили статистический U-критерий Манна–Уитни; коэффициент ранговой корреляции Спирмена. Результаты. В зависимости от действий респондентов после ограничения доступа к социальной сети Instagram* (продолжение использования с помощью приложений VPN, прекращение использования после запрета) изменяются копинг-стратегии и особенности социально-психологической адаптации к стрессовым ситуациям. У респондентов,  которые прекратили использование социальной сети Instagram*, выявлен более высокий уровень избегания и импульсивных действий, меньшая выраженность внутреннего контроля, адаптивности, эмоционального дискомфорта, чем у респондентов, которые продолжили пользоваться данной социальной сетью. Обсуждение результатов. Исследования информационного поведения как отечественными, так и зарубежными авторами подчеркивают важность виртуального пространства социальных сетей как способа самопрезентации, коммуникации, получения поддержки, самовыражения и проч., что согласуется с нашими результатами о том, что ограничение доступа к популярному у молодежи ресурсу Instagram*, может восприниматься как фрустрирующее событие, потеря «части» жизни, которое активирует определенные копинг-стратегии и механизмы социально-психологической адаптации.
Эффект числовой пропорции при оценке размеров и количества в разных форматах
Authors: Кузьмина Юлия В. , Маракшина Юлия А. , Лобаскова Марина М. , Малых Сергей Б.
Published: April 2023

Введение. В исследовательской литературе обсуждается вопрос о наличии общей системы оценки количества и величин. Одним из доказательств наличия общей системы является эффект числовой пропорции, проявляющийся в увеличении времени ответа и снижении точности при возрастании числовой пропорции между сравниваемыми множествами или величинами, обнаруживаемый в заданиях на сравнение. Текущее исследование направлено на исследование взаимосвязей между системами оценки величин и оценки количества с помощью оценки эффектов числовой пропорции для разного типа тестов и форматов предъявления стимулов в тесте на сравнение количества.  Методы. Выборку составили 83 студента (из них 20% мужчин, средний возраст 20,34 года). Участники исследования выполняли задания на несимволическое сравнение, сравнение площадей сложных фигур, сравнение количества и числа. В тесте на несимволическое сравнение использовано два формата предъявления стимулов: раздельный/гомогенный и смешанный/гетерогенный. Для каждого теста рассчитана точность и эффект пропорции. Результаты. Эффект пропорции был значим в тестах на несимволическое сравнение (в обоих форматах) и в тесте на оценку количества, но незначим в тесте на сравнение величин. Эффекты пропорции для разных тестов не коррелируют друг с другом. Также показано, что точность оценки величин коррелирует с результатами теста на несимволическое сравнение, причем эта связь была выше для смешанного/гетерогенного формата. Обсуждение результатов. Впервые получены данные о том, что связь между системами оценки величин и количества может варьироваться в разных условиях предъявления стимулов, что позволяет уточнить существующие теоретические модели работы систем оценки количества без использования символов. Полученные результаты не могут быть полностью объяснены теорией о единой системе оценки количества и величин. Однако показано, что система оценки величин также вовлечена в оценку количества.
Роль общественной организации в социализации инвалидов с детства и лиц, ставших инвалидами в совершеннолетнем возрасте
Authors: Тельминова Кира В.
Published: April 2023

Введение. Целью исследования является выявление роли общественной организации для социализации инвалидов с детства и лиц, ставших инвалидами в совершеннолетнем возрасте. Обзор схожих научных работ показал, что данный аспект социализации инвалидов остается практически без внимания исследователей. При этом, на наш взгляд, дифференцированный подход к изучению процесса социализации инвалидов, включающий углубленный анализ формирования социально-психологических особенностей личности, способствует повышению качества исследования вопросов социализации. Это обуславливает новизну представленной работы, а также может способствовать повышению эффективности практических мероприятий и в целом всей деятельности общественной организации инвалидов. Методы. Методом исследования выступает неструктурированное интервью, раскрывающее мотивы вступления лиц с различным временем наступления инвалидности в общественную организацию инвалидов, динамику их социально-психологического состояния и социального поведения – как в организации, так и за ее пределами. Процедура неструктурированного интервью представляла собой беседу о значении для человека деятельности общественной организации. Была обеспечена атмосфера для свободной формулировки своего опыта. Результаты. Результатом исследования стало понимание того, что в процессе деятельности общественной организации совершеннолетние инвалиды с детства получают новый социальный опыт, в результате которого происходят переоценка и коррекция своих социальных и физических возможностей. Выяснено, что для лиц, ставших инвалидами в совершеннолетнем возрасте, общественная организация формирует социальную среду, позволяющую продолжать трудовую стадию процесса социализации. Обсуждение результатов. Общественная организация выступает в качестве пространства формирования и развития социально-психологических качеств (прежде всего, способствующих коммуникационным возможностям личности). Общественная организация позволяет реализовать социально-психологические качества совершеннолетних инвалидов с детства в полном объеме. Для лиц, ставших инвалидами в совершеннолетнем возрасте, общественная организация является важным элементом института социализации, на платформе которой реализуются социально-психологические качества.