bluuebunny/crossref_metadata_2025 huggingface dataset:
The powers of the bodies of the Social Fund of Russia to control the validity of social security
Authors: Kurchenko O. S.
Published: June 2024

The subject of the study is the norms of Russian legislation providing for the rights and obligations of the bodies of the Social Fund of Russia (SFR) to control the validity of social security. The variety of legal acts that regulate social security relations with the participation of SFR bodies makes it difficult to form a holistic view of the system of powers of these bodies to control the validity of social payments and services provided by the SFR.

The purpose of the study is to systematize knowledge about the powers of the SFR bodies to control the validity of social security, to assess the current legal regulation in this part for its integrity and sufficiency to ensure targeted spending of the SFR budget.

Methodology. Formal legal and comparative legal methods were used to achieve this goal. The research is based on the analysis of the norms of legislation on social security, which enshrine the rights of the SFR bodies to verify information and documents necessary for the appointment and payment of social security, and the practice of its application.

The main results. These rights, in fact, represent the powers of the SFR bodies. The author proposes a classification of the control powers of the SFR bodies in the field under consideration for various reasons. The shortcomings of the current legal regulation of the implementation of control powers by the SFR bodies have been identified.

Conclusions. In order to create a holistic legal framework for controlling the validity of social security provided by the SFR bodies, it is proposed to consolidate the powers of control in a generalized form in the Law on the Social Fund of Russia with the possibility of specifying them in other normative legal acts. At the same time, legal regulation should determine the actual basis for the use of the verification powers and the procedure for their implementation. As one of the directions of further research, the author identifies the question of the relationship between the control powers of the SFR bodies and the obligations of the recipient citizen to inform the SFR body about the circumstances entailing the termination of the right to social benefits or a change in its size.
Xanthogranulomatous Pyelonephritis: An Uncommon Form of Pyelonephritis Highlighted in a Case Report
Authors: Oliveira Danielle Malavazi , Lacerda Bárbara Sthefany de Paula , Hemerly Matheus Compart , Santos Maria Isabel Lima dos , Luchi Weverton Machado
Published: June 2024

Xanthogranulomatous pyelonephritis is a rare and aggressive variant of pyelonephritis, characterized by chronic granulomatous inflammation that progresses to destruction of the renal parenchyma and renal failure. Early diagnosis is a challenge. We present the case of a 7-year-old girl with high fever, associated with low back pain, anorexia and vomiting for 30 days. After antibiotic therapy, radical nephrectomy was required for definitive treatment. Due to its rare and aggressive nature, which often leads to the loss of the affected kidney, it is essential to alert healthcare professionals about the importance of early diagnosis to prevent disease progression and improve the patient's prognosis. We will use a case report to explore the clinical, radiological and pathological aspects related to xanthogranulomatous pyelonephritis.
System for university and college admission projects: Design and Implementation based on Linear Programming
Authors: Nguyen Tan Phu , Nguyen Phan Tu , Le Anh Xuan , Vi Nhat Binh
Published: June 2024

The rapid development of information technology and network infrastructure has brought about numerous opportunities and breakthrough applications in management and operations across all sectors of modern life, with education holding a significant position. Currently, the Ministry of Education and Training has implemented transactional portals to support universities and colleges in constructing admission plans. However, these transactional portals only provide basic support such as uploading data on lecturers, floor area, student scale, and some forms and reports. Despite some improvements, these systems are still incomplete and not consistently updated with admission plan data over the years. Additionally, there is no automated mechanism to propose an optimal solution for balancing the faculty size, student scale, and floor area to estimate admission targets for specific fields and disciplines. Therefore, we propose a new solution: building a web-based system integrated with linear programming algorithms. The goal is to optimize the admission process, balance the faculty, minimize errors, and enhance efficiency, thereby fixing the limitations of the current Ministry's system.
77 NUMARALI GALATA ŞER'İYYE SİCİLİNİN TANITIMI VE TASNİFİ (H.1064-1065 / M. 1654-1655)
Authors: Sönmez Emel
Published: June 2024

77 Numaralı Galata Şer'iyye Sicilinin tanıtımı ve tasnifi
АЛГОРИТМ РЕШЕНИЯ СИНГУЛЯРНО-ВОЗМУЩЕННОЙ ДИСКРЕТНОЙ ЗАДАЧИ ОПТИМАЛЬНОГО ПРОГРАММНОГО УПРАВЛЕНИЯ
Authors: Аширбаев Бейшембек , Алтымышова Жыргал
Published: June 2024

В статье исследуется линейная сингулярно-возмущенная дискретная задача оптимального программного управления с малым шагом. На основе совместного использования методов разделения движений и моментов предложен алгоритм построения равномерного нулевого асимптотического решения рассмотренной задачи. Алгоритм решения задачи построена для асимптотической линейной сингулярно-возмущенной дискретной системы, которая аппроксимирует эквивалентную систему, полученной при полном разделении переменных состояния исходной системы, и она состоит из двух подсистем низкого порядка, решения которых находится независимо, причем они связаны с управляющей функцией. Поправка к следующим приближениям не представляет трудности, так как все изложенные процедуры аналогично повторяются и для всех высших приближений.
Timurlularda Din-Devlet İlişkisi, Musa Şamil Yüksel, (Ankara: Türk Tarih Kurumu,2021) 252 sayfa, 2.Baskı ISBN: 978-975-16-2192-4
Authors: Eker Mehmet
Published: June 2024

Bu kitap değerlendirmesinde Musa Şamil Yüksel’in doktora tezi olarak hazırladığı eseri tanıtılmaktadır. Eser, Timurlular (1370-1507) döneminde din ve devlet ilişkisini konu edinmektedir. Timurlu hükümdarlarının bireysel dindarlıkları ve din anlayışlarının devlet yöntemine yansımaları akıcı bir üslupla ele alınmıştır. Eser literatüre kültür tarihi yönünden katkı sağlamaktadır. Çalışmada, tartışmaya açık cümleler, sıklıkla düşülen tekrarlar, dipnot kullanımında benimsenen usul gibi sorun teşkil edecek taraflar vardır. Bu değerlendirmede tartışmaya açık cümleler incelenmiş, kitabın eksik olarak görülen yönlerinin giderilmesine dair öneriler sunulmuştur.
Các yếu tố ảnh hưởng đến ý định mua thực phẩm hữu cơ của người tiêu dùng tại thành phố Thủ Dầu Một
Authors: Nhớ Trần Thị Kim
Published: June 2024

Nghiên cứu nhằm xác định các yếu tố ảnh hưởng đến ý định mua thực phẩm hữu cơ của người tiêu dùng tại thành phố Thủ Dầu Một. Dữ liệu được thu thập từ 318 người tiêu dùng trên địa bàn có ý định mua thực phẩm hữu cơ. Kết quả từ mô hình phương trình cấu trúc bình phương nhỏ nhất một phần (PLS-SEM) chỉ ra rằng, thái độ, niềm tin, nhận thức về chất lượng, chuẩn mực chủ quan, sự quan tâm đến sức khỏe, sự quan tâm đến môi trường, nhận thức về giá có ảnh hưởng tích cực đến ý định mua thực phẩm hữu cơ. Thông tin minh bạch có ảnh hưởng tích cực đến thái độ và niềm tin. Dựa vào kết quả nghiên cứu, tác giả đưa ra một số hàm ý quản trị nhằm giúp các cửa hàng và các doanh nghiệp kinh doanh thực phẩm hữu cơ hoạch định các chiến lược để gia tăng ý định mua thực phẩm hữu cơ của người tiêu dùng tại thành phố Thủ Dầu Một.
Tác động của tham nhũng đến kinh tế ngầm: Nghiên cứu tại các quốc gia đang phát triển Châu Á
Authors: Hằng Trần Xuân
Published: June 2024

Bài viết nghiên cứu tác động của tham nhũng đến qui mô kinh tế ngầm tại 24 quốc gia đang phát triển khu vực Châu Á giai đoạn 2005 - 2021. Mặc dù cả tham nhũng và kinh tế ngầm là những đại lượng rất khó đo lường và cho đến hiện nay vẫn chưa có chỉ số nào có thể đo lường một cách chính xác được, nhưng việc sử dụng chỉ số CPI là sự đánh giá nhận thức về tham nhũng của công dân đối với khu vực công và chỉ số kinh tế ngầm được xây dựng bởi tác giả Schneider, Buehn và Montenegro (2010) theo phương MIMIC được xem là sự kết hợp phù hợp cho bối cảnh nghiên cứu. Theo khung phân tích lý thuyết, nghiên cứu này sử dụng các phương pháp ước lượng FEM và SYS – GMM đối với dữ liệu bảng để xem xét tác động của tham nhũng đến kinh tế ngầm. Kết quả thực nghiệm cho thấy, tham nhũng đóng vai trò hỗ trợ cho quy mô kinh tế ngầm tại các quốc gia đang phát triển Châu Á. Điều này cho thấy, tham nhũng nhiều hơn làm tăng quy mô của nền kinh tế ngầm vì khi đó chi phí hoạt động kinh tế chính thức lớn. Kết quả này còn hỗ trợ mạnh mẽ cho  nhận định “bôi trơn bánh xe” bởi vì hối lộ tạo điều kiện thiết lập cho các hoạt động ngầm tại các quốc gia đang phát triển. Vì vậy, các quốc gia đang phát muốn  giảm thiểu qui mô kinh tế ngầm cần loại bỏ tham nhũng bằng những hình thức như xây dựng chính phủ điện tử, xây dựng hệ thống thể chế chặt chẽ.
Đánh giá ảnh hưởng của biển đổi khí hậu, vốn con người, phát triển tài chính và năng lượng tái tạo đến sản xuất nông nghiệp tại Việt Nam
Authors: Hưng Ngô Thái , Dũng Phạm Tiến , Hoàng Lại Kim , Hằng Võ Thúy , Sơn Võ Hồng
Published: June 2024

Nghiên cứu đánh giá tác động của biến đổi khí hậu, vốn nhân lực, phát triển tài chính và năng lượng tái tạo đến sản xuất nông nghiệp ở Việt Nam trong thời đoạn từ 1995 đến 2023. Sử dụng phương pháp Wavelet và kiểm định quan hệ nhân quả quang phổ của, kết quả nghiên cứu tại Việt Nam trong giai đoạn thực nghiệm giữa biến đổi khí hậu, vốn nhân lực, phát triển tài chính và năng lượng tái tạo có mối tương quan hai chiều với sản xuất nông nghiệp tại Việt Nam. Không những thế, tồn tại tác động dương vốn con người, phát triển tài chính, năng lượng tái tạo, tác động âm của biến đổi khí hậu tại hầu hết chuỗi thời gian, nghĩa là vốn con người, phát triển tài chính, năng lượng tái tạo thúc đẩy sản xuất nông nghiệp còn biến đổi khí hậu làm suy giảm sản xuất nông nghiệp. Kiểm định quan hệ nhân quả quang phổ cho thấy, tồn tại quan hệ hai chiều giữa biến đổi khí hậu, vốn con người, phát triển tài chính và năng lượng tái tạo đến sản xuất nông nghiệp tại Việt Nam. Trong ngắn hạn, biến đổi khí hậu và phát triển tài chính tác động đáng kể đến việc sản xuất nông nghiệp. Trong dài hạn, để có nền nông nghiệp sạch và bền vững tại Việt Nam, cần quan tâm thúc đẩy phát triển nguồn nhân lực và năng lượng sạch. Ngoài ra, các chính sách tài chính có thể hỗ trợ nguồn vốn nhân lực, năng lượng tái tạo và làm cải thiện biến đổi khí hậu và thúc đẩy sản xuất nông nghiệp. Chính phủ cần xây dựng các chính sách công bằng, rành mạch, ổn định trong dài hạn về đào tạo nguồn vốn nhân lực, các phương thức khích lệ vốn đầu tư tư nhân và vốn đầu tư nước ngoài tham gia vào việc phát triển năng lượng sạch, năng lượng tái tạo.
Kinh nghiệm quốc tế về định giá các-bon và hàm ý cho Việt Nam
Authors: Nga Phan Thị Hằng , Thoa Phan Ngọc Kim , Hằng Nguyễn Thị Minh
Published: June 2024

Mục tiêu của bài viết là nghiên cứu về hoạt động định giá các bon của một số quốc gia trên thể giới như Mỹ, Hàn quốc, Singapore, Trung Quốc. Với mỗi mô hình sẽ được nhóm nghiên cứu phân tích, phương thức triển khai, hiệu quả của từng mô hình, từ đó đề xuất mô hình phù hợp cho Việt Nam. Kết quả nghiên cứu cho thấy, hiện nay có 02 mô hình đề định giá các-bon được sử dụng phổ biến. Một là định giá các-bon thông qua chính sách thuế các-bon, hai là áp dụng hệ thống giao dịch hạn ngạch phát thải (ETS) theo cơ chế “Cap and Trade”. Mỗi mô hình đều có ưu điểm và hạn chế của nó, xét về điều kiện và thị trường của Việt Nam thì nhóm nghiên cứu đề xuất mô hình định giá các-bon theo hạn ngạch phát thải (ETS) là phù hợp.
Improved method for preparation of 4,5-dichlorophthalonitrile and synthesis of 4-chloro-5-(R-amino)phthalonitriles on its basis
Authors: Baklagin Vyacheslav , Baklagin Vladimir , Molchanova Kristina , Abramov Igor
Published: June 2024

The paper investigates the influence of the nature of N-nucleophiles on the reaction of activated aromatic nucleophilic substitution of chlorine atom in 4,5-dichlorophthalonitrile. The authors synthesised 4-chloro-5-(R-amino)phthalonitriles not described in the literature. They are promising compounds for the synthesis of phthalocyanines with increased organosolubility.
Textual geolocation in Hebrew: mapping challenges via natural place description analysis
Authors: Bauman Tal , Paz-Argaman Tzuf , Mondshine Itai , Tsarfaty Reut , Omer Itzhak , Dalyot Sagi
Published: June 2024

Describing where a place is situated is an innate communication skill that relies on spatial cognition, spatial reasoning, and linguistic systems. Accordingly, textual geolocation, a task for retrieving the coordinates of a place from linguistic descriptions, requires computerized spatial inference and natural language understanding. Yet, machine-based textual geolocation is currently limited, mainly due to the lack of rich geo-textual datasets necessitated to train natural language models that, in-turn, cannot adequately interpret the language-based expressions. These limitations are intensified in morphologically rich and resource-poor languages, such as Hebrew. This study aims to analyze and understand the linguistic systems used for place descriptions in Hebrew, later to be used to train machine learning natural language models. A novel crowdsourced geo-textual dataset is developed, composed of 5,695 written place descriptions provided by 1,554 native Hebrew speakers. All place descriptions rely on memory only, which increases spatial vagueness and requires referring expression resolution. Qualitative linguistic analysis of place descriptions shows that geospatial reasoning is greatly used in Hebrew, while empirical analysis with textual geolocation engines indicates that literal descriptions pose challenges for existing methods, as they require real understanding of space and geospatial references and cannot simply be geolocated by matching gazetteer with textual geo-entity extractions. The findings offer improved understanding of the challenges entailed in natural language processing of Hebrew geolocation, contributing to formalizing computerized systems used in future machine learning models for complex geographic information retrieval tasks.
TRAJİK DENEYİM ÜZERİNE BİR İNCELEME: KUSURSUZLAR
Authors: Körük Türker
Published: June 2024

Bu çalışma Kusursuzlar filminde “trajik deneyim” olgusunun kadın karakterlerin ne tür eylemleri sonucunda yaşandığını ve bu deneyimin nasıl eylemlere yol açtığını ele almaktadır.
Trajedinin günümüzde geçerliliğini ve uygulanabilirliğini sosyo-kültürel ve psiko-sosyal alan içinde analiz etmek çalışmanın ana hedefidir. Trajedi olgusu tartışmalarına odaklanan fikirlerle birlikte, trajedi olgusunu bir sanat, düşünce, gerçeklik ve “deneyim” olarak evrensel ve sanatsal biçiminden ayrı ve özgün bir kavram olarak ortaya koymak, özellikle “kadın özne” bağlamında bu deneyimin tarihsel-düşünsel yolculuğuna da ışık tutmaktadır.
Film Goffman’ın Çerçeveleme Analizi yöntemine göre analiz edilmiş ve karakterlerin yaşadığı trajik deneyimlerin sunulduğu ana çerçeveler ve kilitler belirlenmiştir. Ayrıca eleştirel bir perspektiften, analiz ettiğimiz filmlerin kadın özneyi ve trajik eylemi hangi açıdan nasıl yansıttığı ve kadın karakterlerin dahil edildiği sosyal sınıfların trajik deneyim bağlamındaki etkinliği tartışılmıştır.
DİJİTAL KAMUSAL ALAN VE ÇOĞULCULUK İLİŞKİSİNİN ANALİZİ: AÇIK RADYO ÖRNEĞİ
Authors: Dukul Aysun
Published: June 2024

Çağdaş medya ekosistemindeki yeni güç hiyerarşileri ve yoğunlaşma biçimleri, çoğulculuk tartışmalarına medya ekonomisi ve teknoloji boyutunu katmıştır. İçerik ve seslerdeki aşırı bolluk, alternatif medyanın bir alt grubu olan topluluk yayıncılığının kamusal görünürlüğünü olumsuz etkilemekte, iletişimsel gücün dağılımında eşitsizliklere neden olmaktadır. Medya işletmelerinin ekonomik yapısı, nasıl gelir elde ettiği ve nereye kullandığı medyanın demokratik çoğulculuğa katkısı açısından önemlidir. Dünyada topluluk radyoculuğu kendini finanse edebilmek için topluluk katılımını tüm değer zincirlerinde etkin şekilde kullanmalıdır. 28 yıldır topluluk yayıncılığını kitlesel fonlama ile sürdüren Açık Radyo’nun Türkiye şartlarından yola çıkılarak ele alınması bu nedenle önemlidir. Araştırmada bir sosyal gerçeklik olan Açık Radyo’yu ekonomi-politik çerçevede anlamlandırmak ve medyanın demokratik çoğulculuğuna etkilerini çözümlemek amaçlanmıştır. Çalışma amacı kapsamında radyonun örgütsel yapısı; bağımsızlığında merkezi rol oynayan gelir ve iş modeli, çoklu platformlarda gerçekleşen ilişkisel emek süreci, çoğulcu demokrasi ve kar amacı gütmeyen yayıncılığa katkıları açısından incelenmiştir. Örnek olay Açık Radyo’nun örgütsel yapısı ve dijital medyadaki konumu, kamusal görünürlük ve fonlamaya etkileri doküman analizi yöntemiyle ele alınmıştır. Yeni teknolojik eşik bekçileri olan algoritmalar ve yapay zeka(AI) uygulamaları, alternatif medyanın kendini görünür kılmasını zorlaştırdığından iletişimsel gücün dağılımını da kapsaması gereken çoğulculuk ve dijital kamusal görünürlük ilişkisi ilişkisel emek teorisiyle değerlendirilmiştir. Çalışmada çoğulculuğa etkisi ve ekonomik sürdürülebilirlik temalarında Açık Radyo’yu özgün kılan bulgulara ve Barabasi’nin ölçekten bağımsız ağ kuramını doğrulayan sonuçlara ulaşılmıştır.
Efektivitas Model Problem Based Learning dengan Pendekatan Kontekstual terhadap Kemampuan Literasi Matematis Siswa
Authors: Noor Nabila Mahmudah , Purwosetiyono FX. Didik , Wardani Bayu
Published: June 2024

Penelitian ini menggunakan metode kuantitatif dan dilaksanakan di SMK Negeri 7 Semarang, dengan tujuan utama untuk mencapai dua hal: pertama, menilai apakah penggunaan model Problem Based Learning (PBL) dengan pendekatan kontekstual dalam materi persamaan lingkaran mampu mencapai Kriteria Ketuntasan Minimal (KKM) serta meningkatkan kemampuan literasi matematis siswa; kedua, untuk mengidentifikasi perbedaan signifikan dalam kemampuan literasi matematis siswa sebelum dan sesudah penerapan model PBL dengan pendekatan kontekstual tersebut. Populasi pada penelitian mencakup keseluruhan siswa kelas XI, dengan sampel diambil dari kelas XI KJIJ 2 yang terdiri dari 36 siswa, dipilih melalui teknik cluster sampling. Desain penelitian yang dipilih adalah pre-eksperimental dengan desain one group pretest-posttest. Instrumen yang digunakan berupa tes soal uraian. Hasil analisis data menunjukkan bahwa: uji one sample t-test diperoleh nilai signifikansi sebesar 0,000 yang berarti mencapai ketuntasan individual dan persentase ketuntasan klasikal sebesar 91,67%.  Pada uji paired t-test memperoleh nilai signifikansi senilai 0,000 yang berarti bahwa nilai siswa antara sebelum dan sesudah diberikan tindakan pembelajaran menggunakan model PBL dengan pendekatan kontekstual mengalami perbedaan dengan rata-rata nilai pretest dari 50,00 menjadi 86,05. Selain itu, menggunakan uji n-gain diperoleh nilai rat-rata 0,7220 yang menunjukkan bahwa efektivitas pembelajaran menggunakan model PBL dengan pendekatan kontekstual berkategori tinggi. Sehingga dapat ditarik kesimpulan bahwa (1) kemampuan literasi matematis siswa yang mengikuti model PBL dengan pendekatan kontekstual pada materi persamaan lingkaran telah mencapai KKM; dan (2) terdapat peningkatan signifikan dalam kemampuan literasi matematis siswa pada materi persamaan lingkaran setelah penerapan model PBL dengan pendekatan kontekstual dibandingkan sebelumnya.
Studi Deskriptif tentang Pemahaman Karier Siswa Kelas X SMA di Kota Madiun
Authors: Susilaningsih Chaterina Yeni , Mudjijanti Fransisca
Published: June 2024

Pemahaman karier menjadi hal yang sangat dibutuhkan. Informasi karier dapat menjadi arah dan kunci di dalam mengarahkan diri menuju pencapaian karier, yaitu pengenalan diri (minat, bakat, potensi), dunia kerja, dan lingkungan. Penelitian ini bertujuan untuk mengetahui pemahaman karier siswa kelas X SMA di Kota Madiun. Metode penelitian yang digunakan adalah kuantitatif deskriptif. Sampel dalam penelitian ini adalah siswa kelas X SMA di Kota Madiun yang mengisi angket 282 siswa. Teknik penetapan sampel menggunakan teknik total sampling, sedangkan teknik analisis menggunakan analisis deskriptif. Hasil penelitian dari 282 siswa diketahui nilai rata-rata hitung (mean) = 96,549 dengan skor minimum 33 dan maksimum 120, dengan standart deviasi 13,957 dan skor median 98,00. Dengan demikian skor ≤ 98,00 menunjukkan bahwa pemahaman karir siswa kelas X rendah, dan skor > 98,00 menunjukkan pemahaman diri siswa kelas X tinggi. Kesimpulan yang dapat diambil berdasarkan skor mode atau skor yang sering muncul sebesar 102 > 98 menunjukkan bahwa pemahaman karir siswa kelas X tinggi dinyatakan dalam beberapa indikator dalam merencanakan karir, mengeksplorasi karir, dan mencari informasi karir.
Designing a Workplace-Based Learning Environment for Learning Health Promotion: A Design-Based Research
Authors: Verhees Myrthe J. M. , Landstra Anneke M. , Engbers Rik , Van De Pol Marjolein H. J. , Huijbregts Renske , Van Meggelen Roos A. , Kuijer-Siebelink Wietske , Laan Roland F. J. M.
Published: June 2024

Introduction: The healthcare landscape has a growing emphasis on health promotion (HP), which makes HP important in the training of future physicians. This study employed design-based research to develop a clerkship focused on HP and to outline design principles for shaping workplace learning environments to promote HP learning. Methods: We evaluated a nursing-home clerkship designed at Radboud University Medical Center in the Netherlands, and refined it over three rounds. Data collection involved individual and group interviews with students and supervisors, as well as observations during clerkship-related meetings and activities. These interactions also facilitated the exchange of perspectives between participants and generation of new design ideas, fostering co-creation of the clerkship design. Data were analyzed through iterative thematic inquiry to inform new design choices and develop design principles. Results: Evolved clerkship designs included an app for capturing practice experiences to discuss in relation to students’ professional roles, loosening the strict assessment structure, and collaborative creation of a practice assignment about ‘Positive Health’. We constructed four design principles, including: to question and discuss students’ professional identity, provide concrete and meaningful assignments, aim for a peer-learner role for supervisors, and foster co-creation of the workplace learning environment. Discussion: Our design principles support the design of workplace-based learning for HP, a subject that is novel within healthcare practice. We find that co-creation of workplace-based learning, which requires embracing uncertainty, is pivotal in this context, for students, practitioners, and educational institutions.
Incobotulinum Toxin-A in Professional Musicians with Focal Task-Specific Dystonia: A Double Blind, Placebo Controlled, Cross-Over Study
Authors: Frucht Steven J. , George Mary Catherine , Pantelyat Alexander , Altenmueller Eckart , Nmashie Alexandra , Jiao Jocelyn M. , Chen Michael , Feng David , Shin Susan , Kaku Michelle C. , Simpson David
Published: June 2024

Background: Musician’s focal task-specific dystonia is a complex disorder of fine motor control, with incomplete understanding of its etiology. There have been relatively few trials of botulinum toxin in upper limb task-specific dystonia, and prior studies have yielded variable results, leading to skepticism regarding the utility of this approach in elite performers.
Methods: We conducted a double-blind, placebo-controlled, randomized, cross-over study of incobotulinum toxin-A in 21 professional musicians with focal upper extremity task-specific dystonia affecting performance on their instrument, using a novel paradigm of initial injections followed by booster injections at two- and four-week intervals. The primary outcome measure was the change in blinded dystonia rating of the active arm by two expert raters using a Clinical Global Impression numeric scale at week 8 compared to enrollment.
Findings: 19 men and 2 women with musicians’ dystonia were enrolled over a six-year period. Nineteen patients completed the study. Analysis of the primary outcome measure in comparison to baseline revealed a change in dystonia severity of P = 0.04 and an improvement in overall musical performance of P = 0.027. No clinically significant weakness was observed, and neutralizing antibodies to toxin were not found.
Interpretation: Despite its small sample size, our study demonstrated a statistically significant benefit of incobotulinum toxin-A injections as a treatment for musicians’ task-specific dystonia. Tailoring the use of toxin with booster injections allowed refinement of dosing strategy and outcomes, with benefits that were meaningful to patients clearly visible on videotaped evaluations. In addition to its application to musicians’ dystonia, this approach may have relevance to optimize application of botulinum toxin in other forms of focal dystonia such as blepharospasm, cervical dystonia, writer’s cramp, and spasmodic dysphonia.
ZİYA GÖKALP’TE İDEAL GENÇLİK TASARIMI
Authors: Çetin Nurullah
Published: June 2024

Ziya Gökalp, 1908 sonrası süreçte hem yıkılmakta ve parçalanmakta olan Osmanlı Devletinin yeniden ayağa kalkması için, hem de dünya Türklüğünün birleşip bütünleşmesi ve kalkınması için Turan Türk Birliği projesini gündeme getirdi. “Kızılelma ülküsü” adını verdiği bu projeyi “Kızılelma” adlı uzun manzumesinde anlattı. Bu ülküyü gerçekleştirmek üzere tasarladığı ideal Türk gençliği için Ay Hanım adını verdiği genç bir kızı rol model olarak seçti. Ay Hanım özellikle eğitim yoluyla Türk gençlerine Türklük, Müslümanlık ve modern batı medeniyeti değerleri kazandıracaktır. Bu sentez aslında Ziya Gökalp’ın “Türkleşmek, İslamlaşmak, Muasırlaşmak” formülüdür. Ziya Gökalp, ”Türk milletindenim, İslam ümmetindenim, Batı medeniyetindenim” diyen bir gençlik tasarlamıştır. Dünyanın her yerine dağılmış olan Türklerin geri kalmasının ve zayıflamasının sebebi, öz millî kültürlerini, dillerini, tarihlerini, kimliklerini, maddi ve manevi değerlerini unutmuş olmaları ve hep yabancı milletlere bağlı kalmalarıdır. Kurtuluş için de yapılması gereken şey, yabancı milletlerin boyunduruğundan kurtulmak, öz Türk benliğini yeniden kazanmak, inançta ve ahlakta İslam imanına ve ahlakına; kültürde, dilde, gelenekte Türk kimliğine bağlı kalarak modern batı bilim ve teknolojisini almaktır.
Holobiont-level responses to elevated temperature and reduced pH in Aiptasia
Authors: MacVittie Sophia , Cuyler Erin , Rose Brandon J , Hall Emily R , Krediet Cory J
Published: June 2024

Cnidarian species are known for complex multi-partner symbioses, but the contributions of these partners to holobiont health is still widely understudied. With rising sea surface temperatures and ocean acidification (OA) increasingly impacting marine habitats it is essential to understand how these environmental changes will impact these partnerships. In this study, we used the tropical anemone Aiptasia (Exaiptasia diaphana) to assess the impact of elevated temperature and/or reduced pH (acidification) on the photo‐ and respiratory-physiology of the holobiont and to detect and describe changes in the associated microbial communities. This study also allowed for investigation of the relative impact of symbiont association by tracking algal density within the anemones throughout the experiment. Using T-RFLP analysis, we compared the physiological responses and changes to the bacterial communities after placement of the Aiptasia in one of four experimental treatments (control: 25 °C + pH 8.0; temperature: 30 °C + pH 8.0; pH: 25 °C + pH 7.7; temperature + pH: 30 °C + pH 7.7). After two months of exposure, anemone photosynthesis and respiration rates in most of the treatments were not significantly different from the control, however, there were significant modifications to the anemone-associated microbial communities among the treatments. Our results demonstrate that exposure to mildly elevated temperature and/or reduced pH does alter the photo‐ and respiratory-physiology and microbiome of Aiptasia, however, Aiptasia may exhibit different physiological responses to ocean acidification/warming compared to other cnidarian species.
Evaluation of the effectiveness of drainage surgery in young people with glaucoma
Authors: Anisimova S. Yu. , Arutyunyan L. L , Anisimov S. I. , Bratchuk A. A. , Pen L.
Published: June 2024

PURPOSE. To evaluate the efficacy of drainage surgery in primary juvenile open-angle glaucoma.

METHODS. The study included 16 patients with glaucoma, they were examined at the East Sight Recovery eye care center. The mean age was 40.2±13.5 years. All patients underwent a standard ophthalmological examination, including additional methods in dynamics. All patients underwent non-penetrating deep sclerectomy (NPDS) with Xenoplast drainage. In two cases, a combined procedure was performed: NPDS and phacoemulsification with intraocular lens implantation (Phaco+IOL). Within a year after surgery, all patients underwent YAG laser goniopuncture of the Descemet's membrane (Descemet's goniopuncture; DGP).

RESULTS. There were no complications in the postoperative period in any of the studied cases, target IOP level was achieved in the long-term postoperative period, and the number of hypotensive drugs used was reduced to 1–3.

CONCLUSIONS. NPDS with Xenoplast drainage in young patients with a diagnosis of primary juvenile open-angle glaucoma is highly effective and leads to stabilization of IOP and structural and functional parameters of the ONH in a long-term (3–5 years).
Clinical and statistical characteristics of primary open-angle glaucoma in patients with age-related cataract in the Khabarovsk territory
Authors: Vasiliev A. V. , Kolenko O. V. , Samokhvalov N. V.
Published: June 2024

PURPOSE. To investigate the clinical and statistical characteristics of primary open-angle glaucoma (POAG) in patients with age-related cataract (ARC) in the Khabarovsk territory of the Russian Federation.

METHODS. The study examined a total of 231 patients (462 eyes), including 113 men and 118 women aged from 55 to 88 years (average 71 years) with ARC and POAG of different stages.

RESULTS. Stage II glaucoma was detected in the maximum number of eyes with ARC, while stages I and III were less common. In 31 eyes (6.7%), there was a terminal stage of POAG. Moreover, only 10 eyes had previously been operated on for glaucoma. The most widely used drugs in patients with stages I and II POAG are prostaglandin analogues, while in stages III and IV — various combinations of hypotensive drugs.

CONCLUSION. Among all studied eyes, 320 (69.2%) (except for stage IV) did not have target intraocular pressure indicators established by the Federal Clinical Recommendations. In regard to the used drug therapy, it should be noted that in 183 eyes (36.9%) two or more hypotensive drugs were prescribed.
Analysis of the effectiveness and safety of implantation of drainage devices in glaucoma surgery
Authors: Volkova N. V. , Iureva T. N. , Kuroyedov A. V.
Published: June 2024

Currently, trabeculectomy in combination with antimetabolites remains the operation of choice in the treatment of both primary and secondary forms of glaucoma, despite the proven side effects and contradictory long-term hypotensive results. At the same time, methods and technologies of glaucoma surgeries are constantly developing, and with the advent of drainage devices (DD), the possibilities for achieving the necessary hypotensive effect and preserving visual functions have significantly improved, even in prognostically unfavorable clinical situations. Drainage devices are used to improve the outflow of intraocular fluid, reduce intraocular pressure and stabilize glaucomatous optic neuropathy. With the expansion of indications for DD implantation in clinical practice, it is important for specialists to know all the advantages and disadvantages of different types of drainage systems, possible complications and methods of their prevention. This review systematizes literature data on the types of DD, indications and nuances of implantation, postoperative IOP level and duration of hypotensive effect, comparative effectiveness, characteristic complications of early and late postoperative periods (hyperfiltration, hypotension, tube extrusion and exposure, trophic defects, cicatricial transformations of tissues around the drainage platform, endothelial dysfunction of the cornea), as well as methods of their prevention and treatment.
MPOWER POLİTİKA PAKETİ KAPSAMINDA UYGULANAN TÜTÜN VERGİLERİ VE TÜRKİYE’YE YÖNELİK ÇIKARIMLAR
Authors: Kalaycı Oflaz Nihal
Published: June 2024

2004 yılında tütün kullanımının kontrolünü sağlamak amacıyla Dünya Sağlık Örgütü Tütün Kontrolü Çerçeve Sözleşmesi imzalanmıştır. Sözleşmenin 6. maddesi tütün tüketimini azaltmak için vergi politikalarını ve tütün ürünlerine ilişkin fiyat politikalarını, sağlık hedeflerine katkıda bulunmak amacıyla benimseyen ve uygulayan tarafları tanımlamaktadır. Sözleşmeye dahil olan ülkelerde vergi artışlarını da içeren MPOWER politika paketi uygulanmaktadır. Türkiye bu sözleşmeye taraf olan ülkelerden biridir. Bu çalışmada, Türkiye’nin 2008-2022 yılları arasında tütün kontrolü kapsamında uyguladığı vergi politikası ele alınmıştır. Türkiye’de tütün üzerinden alınan vergilerin Dünya Sağlık Örgütü’nün benimsediği kriterlere genel olarak uyumlu olduğu ancak MPOWER politikalarının ülkedeki kapsamı açısından en yavaş ilerleyen ölçüt olduğu görülmüştür. Bununla birlikte Türkiye’de tütün üzerinden alınan vergilerin ve sigara fiyatlarının tütün kullanım yaygınlığı üzerindeki etkisinin istenen düzeyde olmadığı tespit edilmiştir.
Innere und äußere Sphäre
Authors: Rüdenauer Ulrich , Lenz Hermann
Published: June 2024

Hermann Lenz, Altersnotizen. 1997–1998. Hrsg. von Hans Dieter Schäfer / Ders., Das unfreiwillige Gedächtnis. Hermann Lenz und seine Altersnotizen. Zwei Bände in einem Umschlag. Ulrich Keicher, Warmbronn 2014. 64 Seiten, 20 Euro
Impact of Ownership-Location-Internalization (OLI) Paradigm and Investment Development Path (IDP) on Gravity Model of Foreign Direct Investments in Eastern Europe and Central Asia (EECA) Region
Authors: Kocúrek Martin
Published: June 2024

This study investigates the impact of OLI paradigm and the IDP on the gravity model of FDI in EECA region. Using panel data from 1995 to 2017, the analysis employs POLS, Fixed Effects, and Random Effects estimation methods to examine the determinants of FDI inflows. The results highlight the significance of the receiving country's GDP and labour market quality as the most consistent and statistically significant factors influencing FDI inflows. The distance between source and receiving countries also exhibits a negative relationship with FDI flows. Other variables, such as the source country's GDP, tertiary education, institutional governance, taxation, infrastructure, foreign exchange rates, and labour costs, do not show consistent or statistically significant effects across the estimation methods. The Fixed Effects model demonstrates the highest explanatory power, suggesting its suitability for capturing the variation in FDI inflows. These findings contribute to understanding the determinants of FDI and provide insights for policymakers and investors. Countries aiming to attract FDI should focus on promoting economic growth, improving labour market conditions, and reducing perceived distances between source and receiving countries.
"Comparative Hemodynamic Effects of Yoga and Zumba in Middle-Aged Women"
Authors: Mathews Dr. Babitha , V. Dr. Raji Nair
Published: June 2024

This meticulously designed study evaluated the impact of Zumba dance training and yoga practices on mean arterial blood pressure (MAP) and resting heart rate (RHR) in middle-aged women. A random group design was employed, involving 45 sedentary middle-aged women with a mean age of 35±1 years, a mean weight of 78.1±1.4 kg, and a mean height of 161±1 cm. The participants were selected from Kerala, India. Before the intervention, the selected subjects were assessed for their MAP and RHR. The participants were then divided into three groups of 15 each: one group underwent eight weeks of yoga practice, another group engaged in eight weeks of Zumba dance training, and the third group served as a control group, receiving no training. Following the eight-week intervention period, post-intervention assessments were conducted to measure the MAP and RHR of the subjects. The collected data were statistically analyzed using covariance (ANCOVA) analysis, with the significance level set at 0.05. The findings, based on rigorous analysis, indicated that both yoga practices and Zumba dance training significantly reduced the mean arterial pressure compared to the control group. Moreover, Zumba training had a more pronounced beneficial effect on resting heart rate than both the yoga practice group and the control group, with these differences being significant at the 0.05 level. These findings are significant as they provide evidence for the potential of Zumba and yoga in improving cardiovascular health in middle-aged women.
Budd-chiari syndrome: case report
Authors: Alves Fernanda N. B. R. , Pedro Wilson Jose S. , Tabata Keyci Shizue Ito , Braga Lenita Vieira , Alves Larissa Rodrigues , Barbosa Júnior Flávio Vecchi , Oliveira Miriã Cândida , Oliveira Luis Vicente Franco , Freitas Júnior Wilson Rodrigues , Cury Adriano Namo
Published: June 2024

Budd-Chiari Syndrome (BCS) is a rare pathological condition characterized by an obstruction of the hepatic venous outflow. It can be classified as primary, due to an intra-luminal venous lesion, or secondary, resulting from extrinsic compression or invasion of the venous system. This study aims to report a case of Budd-Chiari Syndrome, emphasizing the importance of diagnosis and treatment in preventing progression to chronic liver disease. We report the case of a 47-year-old patient who presented to the emergency department with severe pain in the right hypochondriac region and abdominal distension. A total abdominal CT scan was performed and revealed thrombosis of the suprahepatic veins, confirming the diagnosis of BCS. The patient developed portal hypertension and signs of chronic liver disease. Treatment was administered with Spironolactone and Marevan. After six months of Marevan use, the patient experienced worsening of the esophageal varices and hematemesis, requiring esophageal variceal band ligation. Liver transplantation was not recommended as the patient's MELD score was 14. Therefore, an accurate diagnosis of BCS is crucial for appropriate therapeutic intervention in order to prevent the progression to chronic liver disease, with permanent damage to liver functionality and the patient’s quality of life.
PENGARUH MOTIVASI BELAJAR SISWA DAN KETERAMPILAN MENGAJAR GURU TERHADAP HASIL BELAJAR SISWA DIKELAS X MATA PELAJARAN EKONOMI DI SMA NEGERI 2 TONDANO
Authors: Karundeng Annastassya Christina , Lempas Jety Deisye , Mamentu Meike Drita
Published: June 2024

ABSTRAK
Penelitian ini bertujuan untuk mengetahui pengaruh motivasi belajar siswa dan keterampilan mengajar guru terhadap hasil belajar siswa dikelas x mata pelajaran ekonomi di sma negeri 2 tondano. Metode penelitan yang di pakai pada penelitan ini adalah metode penelitian kuantitatif. Populasi dalam penelitian ini 55 siswa dana sampel 48 siswa.  Hasil uji simultan (bersama-sama ) menujukkan bahwa  Motivasi Belajar,  (X1) dan  Keterampilan Mengajar Guru (X2) berpengaruh signifikan dan positif terhadap variable hasil belajar (Y). Nilai Fhitung  yang diperoleh sebesar 20,45 artinya  Fhitung  Ftabel = Fhitung  Ftabel =20,45 3,20 pada taraf signifikan 0,05 atau 5%. Nilai R square sebesar 0.833  atau 83,3 % yang berarti bahwa hubungan antara varaibel Motivasi Belajar,  (X1) dan  Keterampilan Mengajar Guru (X2)  dengan hasil belajar siswa (Y) memiliki hubungan yang kuat.
Kata Kunci:  Motivasi Belajar Siswa, Ketrampilan Mengajar Guru, Hasil Belajar Siswa
 
 
ABSTRACT
This research aims to determine the influence of student learning motivation and teacher teaching skills on student learning outcomes in class x economics subjects at SMA Negeri 2 Tondano. The research method used in this research is a quantitative research method. The population in this study was 55 students and the sample was 48 students. Simultaneous test results (together) show that Learning Motivation, (X1) and Teacher Teaching Skills (X2) have a significant and positive effect on the learning outcome variable (Y). The Fcount value obtained is 20.45, meaning Fcount > Ftable = Fcount > Ftable = 20.45 > 3.20 at a significance level of 0.05 or 5%. The R square value is 0.833 or 83.3%, which means that the relationship between the variables Learning Motivation, (X1) and Teacher Teaching Skills (X2) and student learning outcomes (Y) has a strong relationship.
Keywords: Student Learning Motivation, Teacher Teaching Skills, Student Learning Outcomes
NATURAL ALKANES FROM Senna siamea AS POSSIBLE CONTENDERS AGAINST INFLAMMATORY DISORDERS: AN IN SILICO AND METABOLOMICS PERSPECTIVE
Authors: Bhattacharya Malay , Arindam Ghosh  , Sourav Chakraborty  , Soumya Majumder  , Sahadeb Sarkar
Published: June 2024

Inflammation is a response to host tissue injury occurring due to irritants or pathogenic infections. It increases levels of cytokines, immune-regulatory factors, cytokine receptors, etc. Cyclooxygenase (COX-1, COX-2, and COX-3) is an enzyme responsible for the formation of prostaglandins. So, by inhibiting this cyclooxygenase-2 enzyme, the treatment of inflammation disorders may be more accessible. Senna siamea is a well-known medicinally important tea plantation shade tree that has anti-inflammatory properties. GC-MS was done to find out the secondary metabolites present in the acetone extract of leaves. Alkanes like undecane,3,8-dimethyl; 2-methyltetracosane, hexadecane, heneicosane, etc. were predominantly detected by GC-MS. In silico studies of eicosane and heptadecane were conducted against pro-inflammatory cytokines like tumor necrosis factor, interleukin-6, and mediator cyclooxygenase. Molecular docking results showed that the two compounds are potential inhibitors of inflammation where eicosane had better binding affinity against all the selected proteins than heptadecane, with both having only one Lipinski violation. Molsoft, Molinspiration, and Swiss-ADMET software were applied to evaluate the two compounds' possible physicochemical, drug-like, and ADMET features. These two compounds can be developed and used as effective inhibitory agents against inflammation; however, more in vitro and in vivo research is needed before conducting clinical trials. Besides the metabolomics-based biosynthesis pathway of two compounds, biosynthetic pathways of other detected compounds were also established, which might help the scientific community to increase the yield of these compounds via the methodology of metabolic bioengineering in order to develop novel pharmaceutical products.
Realization of Vessel Productivity Enhancement via Comparative Analysis of Liner Services: A case of Qasim International Container Terminal (QICT) DP World, Karachi
Authors: Afzal Muhammad Kashif , Zohaib Hafiz Shahrukh
Published: June 2024

The landscape of the shipping industry is constantly evolving. The key aspect point among numerous issues is the efficiency of container loading and offloading on the quayside. This research aims to analyze the performance of Qasim International Container Terminal (QICT) DP World Karachi, Pakistan via Key Performance Indicators (KPIs) evaluation, based on data gathered fqictfrom QICT, and to find the critical factors affecting the overall productivity of QICT. Comparative analysis of liner services of Maersk between Mawingu (MWG) Express and Jade Express was performed via KPI’s data collection from the Operation Department of QICT. This research concludes that vessel Productivity is reliant upon several factors. The most significant among all is the competence of the operator, number of quay cranes utilized at the terminal, number of transfer vehicles, berth allocation, and yard utilization. The study recommends to the terminal regarding optimum number of crane allocation and appropriate yard management to enhance the productivity of the JADE liner service via proactive maintenance of the shipto-shore cranes.
BİR TİCARİ MARKA OLARAK SPOR KULÜPLERİNDE KRİZ İLETİŞİMİ UYGULAMALARINDA SOSYAL MEDYANIN ÖNEMİ: 2023 SÜPER KUPA FİNAL KARŞILAŞMASI
Authors: Ünlü Simge , Gürel Boran Tuğçe
Published: June 2024

Günümüzde, işletmelerin karşılaştığı krizlerde etkili iletişim kurmalarının, kurumsal başarı ile doğru orantılı olduğu gözlemlenmektedir. Yeni medya düzeni içerisinde sosyal medya hesaplarının kriz esnasında kullanımının önemli olduğu düşünülmektedir. Bu kapsamda çalışmanın amacı spor kulüplerinin kriz sürecinde sosyal medya ortam ve araçlarını ne oranda kullandığına yönelik saptamalarda bulunmak olarak belirlenmiştir. Bu amaç ışığında gerçekleştirilen literatür taramasında yayımlanmış çalışmaya rastlanmaması, araştırmanın güncel bir konuyu ele alarak literatüre katkı sağlaması açısından önem ve özgünlüğünü ortaya koymaktadır. Araştırmanın amacı doğrultusunda; 29 Aralık 2023 tarihinde Fenerbahçe ve Galatasaray arasında oynanması planlanan Süper Kupa Finali içerisinde Suudi Arabistan’da meydana gelen kriz kapsamında, takımların kurumsal X hesapları incelenmeye tabi tutulmuştur. Çalışma içerisinde içerik analizi yöntemi kullanılarak; kriz sırasında verilen tepkileri analiz etmek, hedef kitleye yapılan açıklamaların incelemesini yapmak ve ne kadar paylaşım yapıldığını ortaya koymak hedeflenmiştir. Araştırmanın sonunda; takımların 29.12.2023–12.01.2024 tarihleri arasında resmi X hesapları üzerinden, krizle ilgili toplam 11 paylaşımda bulundukları tespit edilmiştir. Bu paylaşımların dokuz tanesi Fenerbahçe Spor Kulübü’ne aitken, iki tanesi Galatasaray Spor Kulübü’ne ait olduğu saptanmıştır. Elde edilen bulgular ışığında takımların ortak açıklama yaptıkları, her iki takımında tüzel kişiler tarafınca açıklamalarda bulunduğu, Fenerbahçe Kulüp Başkanı’nın ayrıca krizle ilgili münferit açıklamada bulunduğu, yazılı, görsel ve videolu olmak üzere çeşitli paylaşımlarda bulunulduğu tespit edilmiştir. Araştırma sonucu olarak, Fenerbahçe Spor Kulübü’nün kriz ile ilgili proaktif bir yaklaşımı benimsemesi ve Kulüp Başkanı’nın bireysel açıklamada bulunmasının, kriz yönetim sürecinde etkili olabileceği düşünülmektedir. Bu bağlamda, Galatasaray Spor Kulübü’nün de daha yoğun bir iletişim programı benimsemesi önerilebilmektedir.
Imparare la musica: un laboratorio del pensare. Una ricerca-azione di Emanuele Pappalardo
Authors: Cianfoni Luca
Published: June 2024

La recensione porta alla luce la metodologia euristica di insegnamento musicale del docente Emanuele Pappalardo, nel suo compimento e nei risultati raggiunti.