bluuebunny/crossref_metadata_2025 huggingface dataset:
GÜZEL SANATLAR LİSELERİ GELENEKSEL TÜRK MÜZİĞİ KORO EĞİTİMİNE YÖNELİK UZMAN GÖRÜŞLERİ
Authors: Güçlü Tükü Nevra
Published: December 2023

Bu araştırmada Güzel Sanatlar Liselerinde uygulanmakta olan Geleneksel Türk Müziği koro eğitimine ilişkin uzmanların görüşlerine başvurarak konuyla ilgili önerilerde bulunmak ve bu öneriler ışığında Geleneksel Türk Müziği koro eğitimi literatürüne katkı sağlamak amaçlanmıştır. Araştırma nitel bir yaklaşımla yürütülmüş, verileri toplamak için görüşme tekniğinden yararlanılmıştır. Bu doğrultuda Kültür ve Turizm Bakanlığı devlet koroları ile TRT Ankara Radyosu koroları bünyesinde çalışmış ya da çalışmakta olan koro şeflerinin görüşleri alınmış ve görüşlerinden elde edilen veriler Nvivo programında analiz edilmiştir. Sonuç olarak Türk Halk Müziği ve Klasik Türk Müziği koro eğitimine yönelik yeni yaklaşımlar elde edilmiş; koroda ses eğitimi, homojenlik, koroda üslup, eser seçimi, eser öğretim süreci ve yorumlama gibi konulara yönelik önerilerde bulunulmuştur.
Relations between Early Educational and Family Experiences and Academic Outcomes of Elementary School Students
Authors: Nisskaya A.K. , Akhmedjanova D.R. , Bayramyan R.M. , Lizunova E.G.
Published: December 2023

This article focuses on the issues of low academic results. Research on the role of children’s early educational experiences highlights the important role of kindergartens, socioeconomic status (SES[1]), cultural capital (CC[2]), and other family characteristics for future educational outcomes. The goal of this paper is to investigate the relationship of SES and CC with academic achievement of children in elementary school, using a sample of 5235 students of the first (n=2574) and fourth (n=2661) grades of secondary schools from the Nizhny Novgorod region of Russia. The academic results were measured using the “Start” and “Progress” tests; the information about family and educational experiences was collected using family surveys. The results suggest that children with low academic achievement typically reside in in rural areas and mostly come from families with low SES. The results indicated that in the fourth grade, the academic results of the children who didn´t attend a kindergarten are higher than the results of the children who did. Nevertheless, this result refers only to a sample of fourth graders with medium and high academic achievement, coming from families with high SES and CC. These results contradict the findings from Russian and foreign studies on the role of early educational experiences. Therefore, the results from this study should be interpreted with caution and require additional rigorous examination. [1] Socio-economic status includes such indicators as level of education of parents, place of residence, family wealth, etc. [17; 19]. [2] Cultural capital includes social attitudes, values, knowledge and educational qualifications [10].
The Role of Periodontitis as Modifiable Risk Factor for Alzheimer’s Disease- A Recent Update
Authors: Poonam Rai  , Yashashree Chande  , Muzzammil Mukadam  , Arvind Shetty
Published: December 2023

Alzheimer’s disease (AD) is among the most common form of dementia affecting geriatric population. Various studies have been carried out to understand the etiopathogenesis of the disease. However, no definite cause has been established and thereby, there is no definite treatment/cure available for eradication of same. The solution for managing the disease is to control the risk factors or triggering factors related to progression or worsening of the condition. Among various risk factors of AD, invasion of the oral pathogens in the brain tissue due to periodontitis (PD) has been associated as risk factor. Various studies had been carried out to state an association between PD and AD. Thereby, this article will discuss most recent evidences available to claim the role of PD as modifiable risk factor in mechanism of AD.
Mesenchymal stem cells in the treatment of ischemic stroke
Authors: Namestnikova Daria D. , Kovalenko Daria B. , Pokusaeva Irina A. , Chudakova Daria A. , Gubskiy Ilya L. , Yarygin Konstantin N. , Baklaushev Vladimir P.
Published: December 2023

Over the past two decades, multiple preclinical studies have shown that transplantation of mesenchymal stem cells leads to a pronounced positive effect in animals with experimental stroke. Based on the promising results of preclinical studies, several clinical trials on the transplantation of mesenchymal stem cells to stroke patients have also been conducted. In this review, we present and analyze the results of completed clinical trials dedicated to the mesenchymal stem cells transplantation in patients with ischemic stroke. According to the obtained results, it can be concluded that transplantation of mesenchymal stem cells is safe and feasible from the economic and biomedical point of view. For the further implementa-tion of this promising approach into the clinical practice, randomized, placebo-controlled, multicenter clinical trials are needed with a large sample of patients and optimized cell transplantation protocols and patient inclusion criteria. In this review we also discuss possi-ble strategies to enhance the effectiveness of cell therapy with the use of mesenchymal stem cells.
Recurrent Psychotic Episodes Induced by Synthetic Cathinones in a Monozygotic Twin with Drug Addiction: A Case Report
Authors: Severtsev Vsevolod V. , Budanova Albina A.
Published: December 2023

We have described a clinical case of psychotic disorder induced by synthetic cathinones in one drug-addicted monozygotic twin. This clinical case is unique, because it offers the opportunity to observe many features of the singularity of the dependence syndrome in twin brothers: drug choice; motivation to use drugs; and the development of multiple, long-lasting psychoses in one of the brothers. We pursued a twelve-month follow-up of this case. The case substantiates the paucity of a fundamental understanding of mental disorders and highlights the importance of further research into the clinical features of drug-induced psychoses, especially those induced by novel psychoactive substances such as synthetic cathinones.
Endoxifen in Treatment of Individuals with Borderline Personality Disorder with Predominant Impulsivity: A Case Series
Authors: Banerjee Debanjan , Ray Rajashree
Published: December 2023

Endoxifen, a protein kinase C inhibitor, has been approved for use in manic episodes in India. One of the symptom traits that it predominantly targets is impulsivity. Impulsivity can also be a symptom dimension of other mental health conditions, one of which is Borderline Personality Disorder (BPD). Management of BPD is challenging, with limited pharmacological options that are symptom-directed and psychotherapy sessions that are fraught with early dropouts and lack of compliance. Impulsive behaviors represent a major reason for seeking help in BPD, especially with regard to non-suicidal self-injury, substance abuse, high-risk sexual behavior, aggression, etc. Here, we present a case series comprising five individuals with a diagnosis of BPD whose treatment regimens were changed and endoxifen added at a dose of 8 mg once daily. Clinical improvement was monitored using the Borderline Evaluation of Severity Over Time (BEST). All the subjects improved in the impulsivity domains as well as with regard to attention deficits, mood fluctuations, and overall functioning. Endoxifen is thus potential promising in terms of the management of BPD, but needs more extensive study to fully substantiate its clinical benefits.
Biological Reductionism as an Obstacle to the Advancement of the Biopsychosocial Concept of Mental Disorders
Authors: Kotsyubinsky Aleksandr P. , Kotsyubinsky Daniil A.
Published: December 2023

The substantial progress in neurobiological technologies has narrowed the horizons of many psychiatrists, ultimately leading them to focus exclusively on biomedical research, primarily aimed at studying the biological basis of mental illnesses. This has led to an unjustified dominance of the biomedical paradigm in understanding the nature of mental disorders, while virtually ignoring the study of other components of the disease related to the psychosocial maladjustment of patients. This trend, largely associated with advancements in neuroscience employing neuroimaging techniques to study the brain’s activity as a biophysical object, has contributed to the development of such innovative field as evidence-based medicine. The methods of evidence-based medicine are seen as adequate in terms of determining the effectiveness of therapy for predominantly biologically determined components of mental illness (including the selection of medications) and only partially for psychological interventions. However, it seems that the predominant use of evidence-based medicine principles is insufficient for a holistic diagnostic approach, which includes a multilevel (diversified) representation of the criteria of effectiveness for pharmacological and psychological interventions. In this regard, it is promising to establish a scientifically and clinically productive combination of, on the one hand, the evidence-based concept of effectiveness assessments based on high-quality randomized scientific studies, and on the other, expert opinions of highly qualified scientific specialists, as well as practicing physicians with their personal professional experience in individualized therapy. This makes it reasonable to develop a personality-oriented personalized psychiatry, based on a biopsychosocial understanding of the nature of mental disorders, their holistic assessment, and the development of comprehensive therapeutic measures.
New method for determining volume of intraoperative blood loss during burn treatment surgery
Authors: Zinovev Evgenii V. , Vagner Denis O. , Chukharev Alexander E.
Published: December 2023

BACKGROUND: Nowadays, there are numerous ways to assess the volume and minimize intraoperative blood loss; however, their effectiveness is subjective. To compare the effectiveness of blood-saving techniques, it is necessary to create new more reliable methods for determining intraoperative blood loss.
AIM: To develop a new technique for determining intraoperative blood loss in the surgical treatment of burn victims.
MATERIALS AND METHODS: In the course of the study, we have developed and proposed our own, original method for determining the volume of intraoperative blood loss, taking into account the indicators of hemoglobin and hematocrit as well as a differentiated calculation of the volume of circulating blood. This technique has been tested on 82 victims with deep burns of the II–III degree (International Classification of Diseases 10th Revision), who were admitted to the department of thermal lesions in the period from April 2021 to December 2021. The data obtained have been processed in the Microsoft Excel 2007 program as well as by generally accepted methods of nonparametric statistics.
RESULTS: The methods currently available have a large variability of results when performing the same intervention. The developed technique shows a stable relationship between the volume of blood loss and the area of the excised scab.
CONCLUSIONS: The data obtained allow to conclude that the new method for determining blood loss in burn victims appears to be a simple and effective method. The new technique will allow to find the most effective methods of minimizing blood loss during surgical necrectomies, which will reduce the need for additional hemotransfusions and promote earlier rehabilitation of burn treatment.
Studying zonulin levels in patients with inflammatory bowel disease and peripheral arthritis
Authors: Khusainova Guzel M. , Nesmeyanova Olga B. , Dolgushina Anastasia I. , Abramovskikh Olga S. , Genkel Vadim V. , Nikushkina Karina V.
Published: December 2023

BACKGROUND: Currently, disruption of the barrier function of the intestinal mucosa is considered one of the key mechanisms in the pathogenesis of extraintestinal manifestations of inflammatory bowel diseases, especially damage to the musculoskeletal system.
AIM: To study the relationship between the level of zonulin in blood serum and the parameters of the immune status in patients with inflammatory bowel diseases in combination with peripheral arthritis.
MATERIALS AND METHODS: 97 patients with ulcerative colitis and Crohn’s disease have been examined, with peripheral arthritis verified in 47 patients; the control group included 50 patients without peripheral arthritis. Zonulin, tumor necrosis factor α, interleukin-1β, -10, -17A, -23 were determined in blood serum using standard kits for direct enzyme immunoassay.
RESULTS: Patients with peripheral arthritis were younger with an earlier onset of inflammatory bowel diseases (p 0.001). When assessing the concentration of serum zonulin in the patients with and without arthritis, no significant differences have been found. In the patients with peripheral arthritis, zonulin concentration directly correlated with the level of interleukin-17A (r = 0.323; p = 0.039), interleukin-23 (r = 0.321; p = 0.041).
CONCLUSIONS: According to the data obtained, the use of zonulin as a marker of peripheral arthritis in inflammatory bowel diseases is not recommended. Nevertheless, the correlation of zonulin and the concentrations of interleukin-17А and -23 demonstrates its role in the regulation of mucosal immunity in the development of extraintestinal manifestations of inflammatory bowel diseases.
Domain Archaea – system overview, metabolism, biotechnological potential
Authors: Zmitrovich Ivan V. , Perelygin Vladimir V. , Zharikov Mikhail V.
Published: December 2023

An overview of Archaea, the most ancient domain of life, was carried out. The phylogenetic relationship of Archaea with bacteria and eukaryotes are considered, and the morpho-physiological characteristics of their main groups are given. The biotechnological potential of Archaea is discussed. Cost-effective products of Archaeal biosynthesis are bacterioruberin, squalene, bacteriorhodopsin and diester/tetraether lipids. The production of other metabolic products of Archaea, such as carotenoids, hydrogen, polyhydroxyalkanoates and methane, are in advanced stages of development. While the biological production of methane and hydrogen currently lags behind the profitability of petrochemical plants, research aimed at enhancing the efficiency of this process with the involvement of Archaea holds strategic significance. Archaea also represent a promising target for application in nanotechnology and bioengineering. The aim of the present review is to unveil the biotechnological potential of Archaea, provide an overview of the main groups within this domain, their morphophysiological characteristics, present a generalized metabolite profile of these groups, and outline the spectrum of productions involving these intriguing microorganisms.
Electromagnetic image recognition of a defect profile on a metal surface with a protective layer based on magnetic disturbance
Authors: Jiang Feng , Hou Rongxi , Tao Li
Published: December 2023

In order to obtain defect information quickly and effectively and improve the accuracy and evaluation ability of traditional electromagnetic non-destructive testing (NDT), an electromagnetic image recognition method for the defect profile based on magnetic field disturbance is proposed
in this paper. The excitation coil structure is designed, the excitation mode of the signal source is optimised and a three-dimensional electromagnetic transient analysis model is established for defect profile identification of a metal surface with an anti-corrosion protective layer. The
research shows that the disturbed magnetic field Bz has the characteristics of high-resolution imaging and symmetry. The orientation of the defect on the surface has different effects on the clarity of image recognition. The larger the angle between the defect boundary and the induced
current, the more complete and clear the image formed by the disturbed magnetic field Bz . A rectangular square wave is the best excitation signal for defect recognition. Its Bz image at t = 0 can present complete shape and position information about the defect. In addition,
the excitation coil structure based on the principle of the disturbed magnetic field must provide a uniform induced current to produce a pronounced disturbed magnetic field. It is concluded that electromagnetic imaging technology based on the disturbed magnetic field Bz can better
detect and characterise the shape of metal surface defects without damaging the metal protective layer and has good application potential for NDT and safety evaluation of in-service equipment.
Faktor yang mempengaruhi pengambilan keputusan metode kontrasepsi non jangka panjang pasangan usia subur Kelurahan Gadingrejo Kecamatan Gadingrejo Kota Pasuruan
Authors: Aziizah Rizka Nuur , Budijanto Budijanto , Deffinika Ifan
Published: December 2023

The use of contraception is a method used in family planning programs to prevent and limit fertility, or delay pregnancy, so as to suppress the rate of population growth. The high rate of attainment of non-MJKP KB acceptors is because these contraceptives tend to be cheaper than the costs required for MKJP contraception, so it is not surprising that the Indonesian population, especially women of childbearing age, choose to use the Non MKJP method. The purpose of this study was to determine the factors that cause couples of childbearing age (PUS) in Gadingrejo Village, Gadingrejo District, Pasuruan to make a decision to choose a non-long-term contraceptive method (Non MKJP). This research is a quantitative descriptive study with a cross section model. The population of the study was 1143 people with sampling using simple random sampling found 92 samples of respondents. The variables studied were social, economic, and demographic factors. Data analysis with logistic regression technique with significant value (Sig less than 0.05). The results of the regression test obtained three significant factors, namely education (Sig 0.008), occupation (Sig 0.005) and duration of contraceptive use (Sig 0.001). Factors of education, occupation, and duration of contraceptive use affect respondents in choosing non-MKJP contraceptives.

Penggunaan kontrasepsi adalah cara yang dilakukan dalam program KB untuk mencegah dan membatasi fertilitas, ataupun menunda kehamilan, sehingga dapat menekan laju pertumbuhan penduduk. Tingginya angka pencapaian akseptor KB Non MJKP sebab alat kontrasepsi ini cenderung lebih murah dibandingkan dengan biaya yang diperlukan untuk kontrasepsi MKJP, maka tidak heran penduduk Indonesia khususnya perempuan usia subur menentukan memakai metode Non MKJP. Tujuan penelitian ini adalah mengetahui faktor penyebab pasangan usia subur (PUS) di Kelurahan Gadingrejo Kecamatan Gadingrejo Pasuruan mengambil keputusan memilih metode kontrasepsi non jangka panjang (Non MKJP). Penelitian ini merupakan penelitian deskriptif kuantitatif dengan model Cross Section. Populasi penelitian berjumlah 1143 jiwa dengan pengambilan sampel menggunakan simple random sampling ditemukan 92 sampel responden. Variabel yang diteliti yaitu faktor sosial, ekonomi, dan demografi. Data analisis dengan teknik regresi logistik dengan nilai signifikan (Sig kurang dari 0.05). Hasil uji regresi didapatkan tiga faktor signifikan yakni pendidikan (Sig 0.008), pekerjaan (Sig 0.005) dan lama pemakaian kontrasepsi (Sig 0.001). Faktor pendidikan, pekerjaan, dan lama pemakaian kontrasepsi mempengaruhi responden dalam pemilihan alat kontrasepsi Non MKJP.
melancolía de Annibale Carracci: consideraciones sobre sus posibles causas y sus consecuencias
Authors: López Chaurri Fernando
Published: December 2023

La vida y la obra de Annibale Carracci en los años posteriores a la finalización de la que fue considerada como su gran obra maestra, la decoración de la Galleria Farnese, estuvieron marcadas de forma creciente por su delicado estado de salud a causa de una enfermedad que no se ha podido precisar, combinada con una profunda melancolía. Los biógrafos y tratadistas del siglo XVII ya dejaron constancia de que en el origen de aquella melancolía pudo encontrarse la escasa recompensa financiera y afectiva que el pintor boloñés recibió de su principal comitente en Roma: el cardenal Odoardo Farnese. En el presente artículo analizamos las posibles causas de esa melancolía, que unida a su enfermedad, condicionó notablemente sus últimos años de vida.
Inhaled corticosteroids administration/withdrawal as a therapeutic continuum for patients with chronic obstructive pulmonary disease in real clinical practice
Authors: Avdeev S. N. , Aisanov Z. R. , Arkhipov V. V. , Belevskiy A. S. , Vizel A. A. , Demko I. V. , Emelyanov A. V. , Zaycev A. A. , Ignatova G. L. , Kniajeskaia N. P. , Kudelya L. M. , Leshchenko I. V. , Ovcharenko S. I. , Sinopalnikov A. I. , Trofimenko I. N. , Fedotov V. D. , Khamitov R. F.
Published: December 2023

Chronic obstructive pulmonary disease (COPD) is a progressing disease. Each exacerbation impairs the patient’s prognosis and increases burden for the healthcare system. The most common maintenance treatment options for COPD include long-acting bronchodilators – β2-agonists (LABA) and long-acting antimuscarinic agents (LAMA), and inhaled glucocorticosteroids (ICS), in fixed/opened double and triple combinations. Triple therapy in subjects with exacerbation history is the most effective way to prevent negative outcomes of the disease. It can reduce the frequency of exacerbations, slow down the disease progression, improve quality of life, and reduce mortality in the long run. On the other hand, the response to triple therapy may change over the time depending on airways inflammation level, infection activity, and exacerbation frequency. Current COPD guidelines propose different indications for therapy escalation and de-escalation (ICS addition/withdrawal) for more personalized and safe treatment. At the same time, many practical issues of this process are still unclear, e.g. how often treatment regimens should be reviewed and what escalation/de-escalation criteria should be prioritized. The authors strongly believe that COPD therapy should adapt a holistic treatment approach (continuum) with quick responses to any changes in the patient’s condition.

The aim of our work was to create an algorithm for ICS administration/ withdrawal for COPD patients on long-acting dual bronchodilators maintenance therapy and to establish a therapeutic continuum that takes into account exacerbation history, symptoms severity, blood eosinophilia level, and concomitant asthma.

Conclusion. This instrument can be a useful and convenient tool for long-term patient management when access to specialized medical care might be restricted. It takes into account the main current recommendations for COPD management and is easy to apply in real clinical practice.
Ten-year analysis of the efficacy of vaccination against pneumococcal infection in patients with chronic obstructive pulmonary disease
Authors: Ignatova G. L. , Avdeev S. N. , Antonov V. N. , Blinova E. V.
Published: December 2023

Major problems in the course of chronic obstructive pulmonary disease (COPD) include frequent exacerbations and related deaths. The use of pneumococcal vaccines, primarily a 13-valent polysaccharide conjugate vaccine, is a generally recognized tool for reducing the number of exacerbations.

The aim of the study was to analyze the prospective clinical efficacy of vaccine prophylaxis with conjugated pneumococcal vaccine Prevenar-13 (PCV13) in patients with COPD over 10 years.

Methods. A total of 362 male patients who were treated or monitored at the Regional Pulmonological Center of Chelyabinsk in 2012 – 2022 were enrolled in the study. The main efficacy endpoints of observation over 10 years were: the dynamics of dyspnea (mMRC score), forced expiratory volume in 1st second, the number of exacerbations, hospitalizations, the number of pneumonias. After confirming the diagnosis of COPD, the patients were divided into two observation groups. The first group (n = 150) included patients vaccinated with PCV13. The second group (n = 212) included patients with COPD who had not received pneumococcal vaccination for various reasons.

Results. Severe forms of the disease and frequent exacerbations predominated in both groups. 96 (27%) deaths were recorded in the PCV13-vaccinated group, and 171 (47%) deaths in the unvaccinated group. The difference between vaccinated and unvaccinated is statistically significant (p < 0.05). In the unvaccinated patients, there was a steady progression of shortness of breath with an increase by 12% compared to baseline (p < 0.05) by the 10th year. A positive trend in FEV1 was noted in patients vaccinated with PCV13. They also showed a significant decrease in BODE prognostic index.

Conclusion. The use of PCV13 allows for stabilization of the main clinical and functional indicators of the respiratory system in patients with COPD in the long term (at least 10 years of follow-up). Vaccination maintains a low risk of adverse events according to the BODE index; an increase in patient survival was noted over a 10-year horizon (odds ratio – 2.35; 95% confidence interval – 1.45; 3.77), including cases with acute viral damage with COVID-19 (COronaVIrus Disease 2019).
The macrostructure of lungs on multislice computed tomography scans in the long-term period after COVID-19 pneumonia
Authors: Kotlyarov P. M. , Soldatov D. G. , Lagkueva I. D. , Tsallagova Z. S. , Solodkiy V. A.
Published: December 2023

The purpose of the study using MSCT monitoring data was to investigate the semiotics of residual changes in the lungs in the long-term period (up to 2 years) after pneumonia associated with COVID-19 (COronaVIrus Disease 2019).

Methods. A comparative analysis of MSCT data of the chest organs was carried out in 146 patients with a confirmed diagnosis of COVID-19-associated pneumonia in 2020 – 2021 and subsequent MSCT monitoring data until 2023. MSCT was performed using a 64-slice computed tomography scanner with data post-processed on the workstation.

Results. Based on the analysis, 4 groups of patients were identified that differed in the severity of viral pneumonia and the prevalence of lung lesions. The first group of patients had the most beneficial course. In 90% of cases, there was a complete resolution of the consequences of viral pneumonia in terms macroscopic changes in lung tissue by the second year of observation. In the second group, which consisted primarily of older people, 27 (52.94%) patients in year 1 and in 33 (64.7%) patients in year 2 showed a recovery of macrostructure. This group demonstrated fibrous cords, reticular changes, reactions of pleura, and residual lesions (“ground glass”). A similar trend, but in a more severe form, was observed in group 3 patients. 40 patients (86.95%) had residual changes similar to those in group 2 (middle, elderly age and older people) with the addition of bronchial wall thickening and bronchiectasis. Only in 2 (22.22%) of 9 patients with atypical manifestations of COVID-19 pneumonia in the form of “crazy paving” changes in the form of reticular seals, fibrous cords, localized thickening of the pleura and lymphadenopathy persisted up to 2 years of observation.

Conclusion. MSCT monitoring of the lungs of patients suffering from COVID-19-associated pneumonia up to 2 years after recovery showed that the prevalence and severity of post-COVID changes in the lungs depends on the severity of the disease (degree and nature of damage to the pulmonary parenchyma) and the patient’s age.
Oscillometry: clinical significance and applications
Authors: Kiryukhina L. D. , Chernyak A. V.
Published: December 2023

Oscillometry (the forced oscillation technique) is widely used in the Russian Federation. It is a simple, noninvasive functional diagnostic test that offers unique advantages in cases where spirometry and other pulmonary function tests are not appropriate, such as in young children, debilitated patients, or patients with physical and cognitive barriers to performing tests that require effort and coordination.

The aim of this study was to analyze scientific literature data and our own results and to evaluate the significance and applications of oscillometry in clinical practice. The review examined the physiological principles of oscillometry and the basis for interpreting the results. Oscillometry is now recognized as a sensitive diagnostic tool for assessing airway resistance. This article describes sensitivity of the method for bronchodilation and bronchoprovocation tests, as well as its response to drug treatment, especially in asthma and chronic obstructive pulmonary disease. Oscillometry is a useful tool for diagnosing obstructive ventilation disorders. It should be used as an addition to spirometry to clarify phenotypes of small airways diseases. However, despite its great promise as a useful diagnostic tool, further evidence of its clinical utility in restrictive conditions is needed.

Conclusion. Thus, oscillometry can be considered an addition and sometimes an alternative to spirometry and bronchodilation test, since it is well standardized. The test results are highly reproducible, the study does not require maximum effort, and the test is carried out during spontaneous tidal breathing.
Management of diabetic ketoacidosis in internal medicine: insulin protocols, electrolyte balance, and clinical outcomes
Authors: Alharbi Samar Abed , Meshari Amjad Mohammed , Henawi Zainab Abdulaziz , Alsaadi Reem Mohammed , Alqarni Shaher Saad , Hani Ali Fuad Al , Alhamrani Ola Hussain , Saptan Laila Mohammed , Hamoud Zainab Abduljabbar Al , Alshanbri Nawaf Khalid , Jafar Zainab Abdulmonem , Farag Abdelrahman
Published: December 2023

Diabetic ketoacidosis (DKA) is a critical complication of diabetes mellitus (DM), characterized by hyper-glycemia, acidosis, and ketosis. It poses a substantial risk of morbidity and mortality, especially in type 1 DM patients. DKA can be triggered by various factors, including insulin deficiency, infections, alcohol abuse, and other medical conditions. Hospital admissions for DKA are increasing, with mortality rates of up to 5-9%, often linked to severe underlying illnesses and complications such as myocardial infarction and stroke. Effective DKA management involves rehydration, correction of electrolyte imbalances, insulin administration, and addressing precipitating factors. Fluid resuscitation with isotonic saline is vital to restore hydration, and continuous intravenous insulin infusion is the preferred method to control blood glucose and suppress ketone production. Electrolyte imbalances, particularly potassium, sodium, phosphate, and magnesium, require careful monitoring and correction. Clinical outcomes in DKA management include resolving acidosis, normalizing blood glucose, and restoring electrolyte balance, all while achieving and maintaining clinical stability. Complications like cerebral edema and acute respiratory distress syndrome can significantly impact the prognosis. Long-term considerations encompass diabetes management, patient education, and follow-up care.
Modeling the maturation process of high performance-oriented child athletes
Authors: Ermilova Anna V.
Published: December 2023

The article considers the problem of growing up of individuals in the sports field of activity aimed at achieving high sports results. Based on the theoretical developments of researchers N. V. Veselkova and E. V. Pryamikova, aimed at identifying the social nature of maturation competence, as well as the author's sociological study «Longevity in high-performance sports», carried out by the method of questionnaire survey of high-class athletes (n=400 people, the sample "snowball"), theoretical and applied research of modeling the maturation process of child athletes aspiring to become high-performance athletes was carried out. Modeling of the process of maturation of this category of population was carried out in two directions: first, the influence of external conditions on the process of maturation - the environment in which the individual is formed; circumstances in which the individual is forced to be and their perception; subjects surrounding the personality and their direct influence on it. Secondly, the influence of internal characteristics of the individual - internal qualities, personality traits, the dominant of which is the ability to cognize oneself, which allowed us to form an internal and external model of growing up. The external model of growing up in the sphere of sport is characterized by a high level of social influence on the subject, contributing to the formation of social thinking in young athletes. The internal model of maturation develops the subjectivity of young athletes to a greater extent, which is facilitated by the process of goal-setting of actions, a high level of responsibility to society for the achieved result. The aggregate of the actor's subjectivity and his social thinking form the internal-external model of actors' maturation in the sports sphere of activity, which allowed the athlete to achieve a high level of sports results.
Performance analysis of OFDM with variations in cyclic prefix and FFT lengths
Authors: Kapse Yogita Dinkar , Mohani Shripad Pralhad
Published: December 2023

Orthogonal Frequency Division Multiplexing (OFDM) is a modern and suitable modulation strategy for commercial high-speed broadband wireless communication systems. This is because wireless services and demands have grown so quickly in recent years. While creating wireless communication, the channel environment is crucial. A square grid with identical vertical and horizontal spacing is used for the constellation points in quadrature amplitude modulation (QAM). More bits can be transferred per symbol to higher-order modulation forms. This research has looked at how Orthogonal Frequency Division Multiplexing OFDM systems perform using different modulation techniques on channels with additive white Gaussian noise (AWGN). Using MATLAB software to do an experiment with different modulation methods and parameters such as FFT length and cyclic prefix findings showed that 64-QAM modulation sends the same amount of data faster and with fewer symbols than QPSK 16-QAM. Here, the 64-QAM modulation technique performs better. An extensive literature survey has been carried out. The work done here involved working on many parameters to improve the performance of OFDM, i.e., by reducing BER, changing modulation techniques, and analyzing the trade-off between cyclic prefix length and Bit Error Rate. Compared to the existing work, the proposed system provides better performance.
Virtual learner experience (VLX)
Authors: Steynberg Johanna , Van Biljon Judy , Pilkington Colin
Published: December 2023

Science educators need tools to assess to what extent learners’ knowledge can be transferred to novel real-world situations. Virtual reality learning environments (VRLEs) offer the possibility of creating authentic tools where situated learning and assessment can take place, but there is a lack of evidence-based guidelines to inform the design and development of the VRLEs focussing on the user, that is the learner experience, especially for secondary schools. Drawing on theoretical premises and guidelines from user experience, usability, and technologically enabled assessment literature, we designed, developed, evaluated, and refined a VRLE prototype for the authentic assessment of knowledge transfer in the secondary school science classroom as guided by the design science research approach. Lessons learnt from the implementation and iterative evaluation of the prototype are presented as a set of literature-based, empirically validated guidelines to support and guide educational designers and developers to create VRLEs focused on supporting the learner experience. The contribution of this study is a VRLE design model with the learner at its core, the definition of VLX to include learner-specific aspects of immersive environments, and guidelines for the development of an effective and efficient virtual reality environment for the assessment of knowledge transfer in science education.
Beszámoló a „Biztosítási piacról jogászoknak, biztosítási jogról közgazdászoknak” című konferenciáról
Authors: Csöndes Mónika
Published: December 2023

Az írás a "Biztosítási piacról jogászoknak, biztosítási jogról közgazdászoknak" címmel 2023. május 10. napján a Budapesti Corvinus Egyetemen rendezett konferenciáról ad összefoglalást, szól a konferencia céljáról, programjáról, fogadtatásáról.
Art Deco Sanat Akımı ile “Bulut” ve “Çintemani” Motiflerinin Yeni Tasarımlarda Kullanımı
Authors: CORUH Ebru , ATALAN Dilara Nur
Published: December 2023

Her kültürün kendine ait motifleri, desenleri, sembol ve simgeleri bulunmaktadır. Bu motifler ait oldukları

medeniyetin kültürü, inanışları, efsane ve mitleri hakkında bilgiler verir. Uzun yıllardır aktarılarak günümüze

gelen motiflerden bir kısmı tek bir millet ile özdeşleşmiş, bir kısmı da birçok milletin ortak noktası haline

gelmiştir.

Farklı inançlar ve farklı zevk unsurları sebebi ile motiflerin birçoğu zaman içerisinde, kültürlerarası

etkileşim sonucunda değişikliğe uğramıştır. Birbirlerinden etkilenerek farklı tarz ve üsluplar ile yorumlanan

motifler günümüzde pek çok alanda tercih edilmekte ve tasarımcılara ilham kaynağı olmaktadır. Bu

çalışma kapsamında “çintemani” ve “bulut” motifleri ele alınarak ejderha motifi ve art deco sanat akımı

eşliğinde yorumlanmıştır. Bu motifler geleneksel Türk sanatları ve Uzak Doğu sanatlarında uzun yıllardır

kullanılmaktadır. Farklı iki kültürün ortak motiflerinden biri olarak, minyatür ve çini sanatlarında en çok

tercih edilen motiflerin başında gelmektedir. Bu çalışmada yeni ve özgün bir tasarım ortaya çıkarılarak,

eskiz çalışması, dijital renklendirmesi ve dijital olarak ürün üzerinde sunumu gösterilmiştir.
Yeni Avrupa Bauhaus Kavramı ile Geleceğe Yönelik Yaşam Biçimlerini Tasarlamak
Authors: BEKCİ Banu
Published: December 2023

Şehirleşmede yaşanan planlama süreçlerindeki başarısızlıklar yöneticiler ve farklı meslek disiplinlerinin

planlama süreçlerine bütüncül yaklaşamamalarından kaynaklanmaktadır. Uluslararası platformlarda

hissedilen bu süreç küresel ve finansal yoksunluğa karşı aranan ekonomik yaklaşımlarda rekabet gücünü

arttırıcı tedbir ve sürdürülebilir tasarım arayışlarını gündeme getirerek kent planlama ve tasarımlarındaki

yapılı çevrelerde yeni bir statükonun sorgulanmasını gündeme getirmiştir. Bu bağlamda Avrupa “Yeşil

Düzen” kavramının küresel etkileri ele alınarak yeşil düzene destek olabilecek sektörlerin neler olacağı, bu

sektörlerin süreçten nasıl destekleneceği ve süreç içerisindeki dönüşümün nasıl ve hangi enstrümanlarla

gerçekleşeceği çalışmanın çıkış noktasını oluşturmaktadır. “Avrupa Yeşil Mutabakatına” paralel olarak

geliştirilen “Avrupa Yeşil Anlaşması” ile yürürlükte olan yasalara yönelik yeni düzenlemelerin ve değişikliklerin

önü açılarak Avrupa ve yakın çevresinin korunması amaçlanmaktadır. Yeni Bauhaus akımı olarak yorumlanan

bu süreç Bauhaus akımının karşılaştığı bütün olumsuz koşulları günümüzde yeşil yenilenme sürecinin bir

başkaldırışı olarak görülmektedir. Çalışmada kentsel mekânlara ait planlamalardaki kolektif diyaloglar

üzerinde durularak “İnsan-Doğa” dengesini koruyan yeşil kentsel planlama süreci hakkında bilgi verilmiştir.
Godność człowieka a prawo do rzetelnego postępowania
Authors: Celińska-Grzegorczyk Katarzyna
Published: December 2023

Godność człowieka wymaga ochrony przez wszystkie władze państwowe. Godność stanowi bazę i źródło wszystkich praw człowieka, w tym również prawa do rzetelnego postępowania. Zadaniem postawionym przed niniejszym opracowaniem jest analiza relacji zachodzącej pomiędzy godnością człowieka, stanowiącą podstawowy punkt odniesienia dla wszystkich podmiotów sprawujących władzę publiczną, a regulacjami procesowymi obowiązującymi w polskim postępowaniu administracyjnym i sądowoadministracyjnym.
Zabezpieczenie rodziny przed przemocą w następstwie wydanego przez policję nakazu opuszczenia mieszkania bądź zbliżania się do niego
Authors: Wolwiak Ireneusz
Published: December 2023

Ustawodawca, dążąc do stworzenia jak najszerszej ochrony prawnej dla przeciwdziałania zjawisku przemocy w rodzinie, nałożył określone obowiązki na organy administracji rządowej i jednostki samorządu terytorialnego. Szczególny zakres tej ochrony powierzono organom Policji, a dla możliwości uzyskania ochrony sądowej wdrożono odrębne postępowanie cywilne. Działania Policji – przy wprowadzaniu po raz pierwszy takiej regulacji – doprowadzą do wydania nakazu opuszczenia lokalu przez sprawcę przemocy lub zakazu zbliżania się do niego. Wydanie tego aktu administracyjnego poprzedzone jest określonymi czynnościami w ramach zawartej w ustawie o Policji procedury pozwalającej na stwierdzenie faktu zaistnienia sytuacji zagrożenia życia lub zdrowia osób dotkniętych przemocą. Powstaje wobec tego konieczność analizy uregulowań prawnych zawartych w różnych ustawach dla wyznaczenia obszaru normatywnego zachowania uczestników tego postępowania, przy jednoczesnym zapewnieniu osobie zobowiązanej do opuszczenia lokalu lub niezbliżania się do niego, dostępu do drogi sądowej. Przeprowadzone badanie ma zarazem pozwolić na stwierdzenie skuteczności ochrony zapewnionej osobom wspólnie zamieszkującym ze sprawcą w następstwie wydanego nakazu opuszczenia lokalu na etapie przymusowej realizacji zobowiązania. Przedmiotem analizy stanie się w końcu dopuszczalność przedłużenia ochrony wynikającej z nakazu Policji na dalszy okres związany z wszczętym postępowaniem sądowym.
¿Cuál es el efecto del rol de las mujeres rurales sobre la adecuada cloración del agua? Evidencia para el caso peruano
Authors: Sotelo Tornero Marisela , Arias Callupe Waldir
Published: December 2023

Esta investigación analiza la relevancia del rol de las mujeres rurales sobre la adecuada cloración del agua, considerando una evaluación a nivel nacional rural, así como las diferencias que existen entre los centros poblados concentrados y dispersos. Este estudio enfoca su análisis en aquellos centros poblados con menos de 2000 habitantes y que son abastecidos en los servicios de agua y alcantarillado por algún prestador rural denominado en Perú organización comunal. De acuerdo con la revisión de la literatura, se sugiere que, una escasa participación de las mujeres en organizaciones comunales representa uno de los factores que contribuyen a que el índice de agua apta para consumo humano siga siendo muy bajo. En esta línea, para llevar a cabo el estudio, se emplearon los datos recopilados del informe Diagnóstico sobre el abastecimiento de agua y saneamiento en el ámbito rural - DATASS 2020, publicado por el Ministerio de Vivienda, Construcción y Saneamiento (MVCS) (2020), que brinda información sobre los servicios de saneamiento en los centros poblados rurales. Las afirmaciones planteadas en la hipótesis se validan en la sección Resultados mediante un análisis de regresión probabilística, utilizando un índice de calidad del servicio de agua que se representa a través de la adecuada cloración de la misma.
Elucidation of biopotentiators in organic based formulation bijamrith from Gir Cow (Bos indicus) excrements and urine using GC-MS
Authors: Sunitha R. , Gayathry G. , Maheshwari P. , Ganesan K. , Suganthy M. , Padmapriya S. , Shenbagavalli S. , Bharani A.
Published: December 2023

Background: Traditional organic formulation bijamrith prepared from fresh urine and dung of cow is an important element in natural farming and extensively applied in modern agriculture practices to improve the soil fertility, control pest and disease in plants. The scientific validation of the biologically active compounds in bijamrith is unexplored. Methods: Bijamrith was prepared from excrements of Gir cow. Since, the volatile low molecular weight organic compounds from cow wastes could be derived from the solvent extract using GC-MS effectively, the compounds were separated by liquid-solvent extraction method using diethyl ether solvent and analyzed by GC-MS. Result: GC-MS analysis revealed the elution of about 40 different compounds in bijamrith formulation. Among them, fatty acid namely 9-octadecenoic acid (Z)-, an ester compound 2,3-dihydroxypropyl occupied higher concentration with peak area of 13.96% at 29.29 minutes of retention time which were reported to possess antifungal, antibacterial and anti-inflammatory activity. The other biologically active compounds eluted were antioxidants, plant growth hormones, nematicidal agents for defense mechanism and improvement of plant health.
Kersting’s Groundnut [Macrotyloma geocarpum (Harms) Maréchal & Baudet] Crop Attracts More Field Pests and Diseases than Reported Before
Authors: Agoyi Eric E
Published: December 2023

It has long been reported that kersting’s groundnut [Macrotyloma geocarpum (Harms) Maréchal & Baudet] is less susceptible to field pests and diseases. Previous reports focused on bruchids and weevils as the major pests exerting biotic stress on the crop. In the process of setting up a breeding program for the crop in Benin, field experiments were established in four research stations and mission trips organized to visit farmers’ fields across the major kersting’s groundnut growing areas of Benin. It was observed that the crop is attacked by many field pests and diseases. In total the crop is attacked by: i) Fungi: wilt disease, white mold disease, rust disease, ii) viruses, iii) invertebrates: aphids, grashoppers, caterpillars, millipedes on pods, and iv) Vertebrates: birds, rodents and rabbits This short communication aims to correct the perceptions of practically no field disease and pest attack so far reported on Macrotyloma geocarpum.
The Ethics of Artificial Intelligence: A Sociological Approach
Authors:   Volgograd State Medical University, Donika Alena D. ,   Volgograd Medical Research Center
Published: December 2023

Background: to create effective mechanisms for state regulation of potential moral challenges caused by the widespread introduction of artificial intelligence technologies, it is of practical interest to study the attitude of society to this problem. The purpose of the work is a sociological analysis of the attitude of the Russian society to the introduction of artificial intelligence technologies. Materials and methods: A comprehensive analysis of data from open access databases of All-Russian Center for the Study of Public Opinion was carried out. The materials of sociological surveys for the period 2007 to 2023 were used. Data weighted by socio-demographic parameters. Results: The majority of respondents believe that AI cannot completely replace humans (78 %). The greatest fears of the popula-tion (noted by 50–65 % of respondents) are associated with the loss of personal data and violation of privacy boundaries, the loss of personal responsibility for erroneous actions. Every third noted the risks of violation of civil rights and social guarantees ("increases in-equality", "violates the balance of interests of society and the individual"), potential ethical problems ("artificial intelligence has no morals and ethics" – 32 %). Conclusion: Distrust of AI technologies is associated with an understanding of the social risks of their integration and an aware-ness of the loss of human values of communication, creativity, and individuality. Particular risks in this context are presented for social institutions of education and healthcare, where the loss of interpersonal communication calls into question the manifestation of empa-thy, sympathy and compassion.