bluuebunny/crossref_metadata_2025 huggingface dataset:
ADSORPSI LOGAM BERAT MENGGUNAKAN ADSORBEN ALAMI PADA AIR LIMBAH INDUSTRI
Authors: Rivania
Published: July 2019

Penulisan ini dilakukan untuk mengurangi logam berat berat yang terdapat pada air limbah industri dengan menggunakan adsorben alami. Pada penulisan ini dilakukan metode batch. Pembuatan adsorben alami efektif dalam proses adsorpsi karena relatif aman terhadap lingkungan dan biaya yang dikeluarkan cukup murah. Pada proses pembuatan adsorben alami, adsorben harus diseragamkan ukurannya agar proses adsorpsi lebih efektif. Adsorben lebih efektif untuk mengadsorpsi apabila di aktivasi secara kimia dan secara fisik. Secara kimia dapat menggunakan larutan asam atau basa tergantung struktur adsorben. Menurut penelitian sebelumnya, untuk adsorben aktivasi yang paling efektif menggunakan larutan asam kuat dengan pengaruh waktu aktivasi. Setelah adsorben aktivasi, untuk menganalisis luas permukaan yang terbentuk dapat menggunakan metode Scanning Electron Microscopy (SEM). Proses adsorpsi memiliki pengaruh terhadap waktu kontak, pH, kecepatan pengadukan , massa adsorben, luas partikel. Beberapa penelitian telah membuktikan bahwa adsorben alami dapat menurunkan logam berat, seperti menggunakan kulit pisang, jerami, kitosan dan kulit udang. Melihat kemampuan adsorben alami yang telah dibuat dalam mengadsorpsi logam berat dapat menggunakan isoterm adsorpsi yang meliputi isoterm langmuir dan menggunakan isoterm freudlich
PENGEMBANGAN KEPROFESIAN BERKELANJUTAN (PKB) BAGI GURU MELALUI PROGRAM INDUKSI GURU PEMULA (PIGP)
Authors: Sulfemi Wahyu Bagja , Arsyad Arsyad
Published: July 2019

Melalui kegiatan pengembangan kompetensi dan profesional berkelanjutan atau continuing competence and professional development (CCPD) akan terwujud guru kompeten dan profesional yang bukan hanya sekedar memiliki ilmu pengetahuan yang kuat, tuntas dan tidak setengah-setengah, tetapi tidak kalah pentingnya juga memiliki kepribadian yang matang, kuat dan seimbang. Dengan penguasaan ilmu pengetahuan dan teknologi yang kuat, tuntas dan tidak setengah-setengah serta kepemilikan kepribadian yang prima, maka diharapkan guru terampil membangkitkan minat peserta didik kepada ilmu pengetahuan dan teknologi melalui penyajian layanan pendidikan yang bermutu. Model pengembangan kompetensi dan profesional berkelanjutanyang sudah ada, yaitu program induksi guru pemula (PIG). Kegiatan PIG sebagai proses pembelajaran bagi guru pemula agar para guru pemula tersebut dapat segera beradaptasi dengan iklmi kerja dan budaya sekolah dan dapat bekerja sebagai guru professional di sekolah, pelaksanaan induksi guru pemula meliputi;persiapan; (2) pengenalan sekolah/madrasah dan lingkungannya; (3) pelaksanaan dan observasi pembelajaran;(4) penilaian; dan pelaporan.
Huey P. Long and the Guarantee Clause
Authors: Magliocca Gerard N.
Published: July 2019

83 Tulane Law Review 1 (2008)
Decreased job security without change in safety during hydrocarbon industry recession
Authors: Sætrevik Bjørn , Ørbeck Sunniva Berge , Helland Maria Vannes , Eid Jarle
Published: July 2019

Economic recessions may decrease an organization’s investment in maintenance, training and safety management, and may thus have a negative impact on safety. The present study examines how job security and safety changed during and after a major recession in the Norwegian hydrocarbon industry. Interviews with HSEQ officers in ship-owning companies informed our hypotheses about what effects the recession may have had on safety perception among crew members. Three cross-sectional surveys of maritime hydrocarbon workers were conducted in 2013 (N = 829), 2015 (N = 444), and 2017 (N = 555). The results showed that although the crew’s perceptions of job security decreased from 2013 to 2017, their perceptions of safety climate did not change. Attitudes to safety and to reporting declined from 2013 to 2015, then improved from 2015 to 2017, indicating that the recession had a temporary effect on the crew’s motivation and intention to comply with the safety regulations. Potential organizational and individual explanations are discussed.
The Five-Factor Personality Inventory for ICD-11: A Facet-Level Assessment of the ICD-11 Trait Model
Authors: Oltmanns Joshua R. , Widiger Thomas A.
Published: July 2019

The ICD-11 includes a dimensional model of personality disorder assessing five domains of maladaptive personality. To avoid unnecessary complexity, the ICD-11 model includes assessment of personality traits only at the domain level. A measure exists to assess the domains of the ICD-11 model (the Personality Inventory for ICD-11; PiCD), yet a more rich and useful assessment of personality is provided at the facet level. We used items from the scales assessing the five-factor model of personality disorder (FFMPD) to develop the Five-Factor Personality Inventory for ICD-11 (FFiCD), a new 121-item, 20-facet, self-report measure of the ICD-11 maladaptive personality domains at the facet level. Further, the FFiCD includes 47 short scales organized beneath the facets—at the “nuance” level. Items were selected and evaluated empirically across two independent data collections, and the resulting scales were further validated in a third data collection. Correlational and factor analytic results comparing the scales of the FFiCD to the five-factor model, PiCD, and Personality Inventory for DSM-5 (PID-5) supported the validity of the theoretical structure of the FFiCD and the ICD-11 model. The FFiCD may be a useful instrument for clinicians and researchers interested in a more specific assessment of maladaptive personality according to the dimensional ICD-11 personality disorder model.
Explaining the Development of Information Security Climate and an Information Security Support Network: A Longitudinal Social Network Analysis
Authors: Dang-Pham Duy , Kautz Karlheinz , Pittayachawan Siddhi , Bruno Vince
Published: July 2019

Behavioural information security (InfoSec) research has studied InfoSec at workplaces through the employees’ perceptions of InfoSec climate, which is determined by observable InfoSec practices performed by their colleagues and direct supervisors. Prior studies have identified the antecedents of a positive InfoSec climate, in particular socialisation through the employees’ discussions of InfoSec-related matters to explain the formation of InfoSec climate based on the employees’ individual cognition. We conceptualise six forms of socialisation as six networks, which comprise employees’ provisions of (1) work advice, (2) organisational updates, (3) personal advice, (4) trust for expertise, (5) InfoSec advice, and (6) InfoSec troubleshooting support. The adoption of a longitudinal social network analysis (SNA), called stochastic actor-oriented modelling (SAOM), enabled us to analyse the changes in the socialising patterns and the InfoSec climate perceptions over time. Consequently, this analysis explains the forming mechanisms of the employees’ InfoSec climate perceptions as well as their socialising process in greater detail. Our findings in relation to the forming mechanisms of InfoSec-related socialisation and InfoSec climate, provide practical recommendations to improve organisational InfoSec. This includes identifying influential employees to diffuse InfoSec knowledge within a workplace. Additionally, this research proposes a novel approach for InfoSec behavioural research through the adoption of SNA methods to study InfoSec-related phenomena.
Anticipating, avoiding, and alleviating measurement error: A synthesis of the literature with practical recommendations
Authors: Zwanenburg Sander Paul , Qureshi Israr
Published: July 2019

Researchers’ ability to draw inferences from their empirical work hinges on the degree of measurement error. The literature in Information Systems and other behavioural disciplines describes a plethora of sources of error. While it helps researchers deal with them when taking specific steps in the measurement process, like modelling constructs, developing instruments, collecting data, and analysing data, it does not provide an overall guide to help them prevent and deal with measurement error. This paper presents a synthesis of the insights in the literature through a decomposition of the logic of measurement. It shows how researchers can classify sources of error, evaluate their impact, and refine their measurement plans, in terms of specific steps or overall measurement approaches. We hope this will aid researchers in anticipating, avoiding, and alleviating error in measurement, and in drawing valid research conclusions.
Preface to the Special Section of Selected Papers from the 28th Australasian Conference on Information Systems
Authors: Indulska Marta , Tuunainen Virpi Kristiina , Riemer Kai
Published: July 2019

Preface to the Special Section of Selected Papers from the 28th Australasian Conference on Information Systems
Criminological aspects of animal abuse
Authors: Vrečko Ines
Published: July 2019

Taking into consideration the complexity of animal cruelty, problems with its varying definitions which depend on legal frameworks, social norms, cultural and public perceptions and many possible approaches to the issue of animal cruelty, this paper will focus only on active cruelty (acts of commission), i.e. the intention to harm an animal and cause pain and suffering. It will study the phenomenon as a multi-indicator for violence.
Regardless of whether animal abuse is treated as a criminal offence or a misdemeanor or if it is absent from the legal framework altogether, it represents a complex phenomenon present in both children and adults. This abuse affects families and a wide range of social institutions, not only harming animals but also indicating various inter-personal types of violence and individual behavioral disorders. This paper explores intersectional and interdisciplinary research on animal abuse, its connection to subsequent adult or concurrent domestic violence and child abuse, contributing factors such as defense mechanisms and the roles of empathy and remorse. Understanding animal cruelty as a part of human violence and as a sign of serious concern for the welfare of both animals and humans is a first step towards building sustainable social policies.
Microstructure and properties of high strength Al-Fe-Cu-Si-Zn alloy (AA8079) produced by mechanical alloying and powder metallurgy
Authors: Meignanamoorthy Meiyanathan , Ravichandran Manickam , Vidhya Vinoth Sundar , Anandakrishnan Veeramani
Published: July 2019

The intent of this work is to synthesize Al-Fe-Cu-Si-Zn alloy (AA8079)at different milling hours, i. e. 1, 10, 20, 30 and 40 h, by mechanical aloying (MA). X-ray diffraction (XRD) and scanning electron microscope (SEM) analysis was carried out for the milled powders. From the SEM images, a significant change in the size and shape of the particle was observed while the milling time was extended from 1 to 40 h. The effect of milling time on properties such as density, hardness and compressive strength was analyzed. After mechanical alloying, the powders were compacted at three different compaction pressures (500 MPa, 550 MPa & 600 MPa) and sintered in a furnace at different temperatures (500 °C, 550 °C & 600 °C) under a controlled atmosphere for 1 h, 2 h and 3 h. An extreme Vickers hardness of 815 MPa and compressive strength of 327 MPa were achieved for 40 h milled powders compacted at 600 MPa, sintered at a temperature of 600°C for a period of 3 h. A optical microscope (OM) and SEM analysis were conducted for the sintered AA8079 samples to study the effect of milling time and PM parameters on the microstructure.
Effect of different grain sizes on the static strain aging behavior of bake hardening steel
Authors: Doğan Tugay , Gündüz Süleyman
Published: July 2019

In this study, the static strain aging behavior of a bake hardening steel (BH 220), suitable for cold forming and widely used in the automotive sector was investigated. Tensile specimens prepared from BH 220 steel were first subjected to a 40 minute solution treatment at 920 °C and 970 °C and then cooled in water to generate various grain sizes. Both as-received and heat-treated samples were pre-strained for 3 % tension and then aged at 180 °C for 10, 20, 30, 60, 180 and 300 min. Tensile tests were carried out to obtain the yield strength (YS), ultimate tensile strength (UTS), elongation (%) and bake hardening value (δY) of aged as-received and heat treated samples. Results indicated that BH 220 steel exhibited static strain aging behavior under as-received and heat-treated conditions. Heat treated samples showed higher susceptibility to static strain aging as compared to the as-received samples. Increased grain size in all the as-received and heat-treated samples decreased the YS and UTS but increased the bake hardening value δY.
Effect of TiBAl inoculation on abrasive wear resistance of high Cr white cast iron
Authors: Teker Tanju , Yilmaz S. Osman , Kerkut Erhan
Published: July 2019

High chromium white cast iron (HCrWCI) is generally used in applications requiring superior wear resistance. The alloys were inoculated with 1–3 wt.-% TiBAl to rearrange the crystallography of the carbides. The alloys were subject toheat treatment at 1000 °C for 1 and 2 h. The microstructuresof the alloys was examined by SEM. Chemical composition was determined by EDS. For wear tests, alloys were tested using 10, 20 and 30 N loads under pin-on-disc wear conditions. Worn surfaces of the alloys were analyzed by SEM. The worst wear resistance was obtained in the alloy inoculated with 3 wt.-%. TiBAl.
Mismeasured Covariate in the Long-Term Survival of Colorectal Cancer
Authors: Azizmohammad Looha Mehdi , Pourhoseingholi Mohamad Amin , Hosseini Seyyed Vahid , Khodakarim Soheila
Published: July 2019

Background: Colorectal cancer (CRC) is one of the most important causes of morbidity and mortality worldwide. This study aimed to determine the effect of measurement error of risk factors on the cure fraction of CRC patients. Materials and Methods: This study was conducted using the medical records of 346 patients with CRC, who were followed up between 2006 and 2017 in Shiraz, Iran. In our data, lymph node ratio (LNR) was a characteristic measuring with error. This variable was used in the model with 0.04 and 0.8 of error variance. Nonmixture nonparametric cure rate model and its corrected forms, simulation-extrapolation (SIMEX) and corrected score (CS), were applied to the data. Results: In noncured cases, the mean survival time was 1115.45 (95% confidence interval, 1043.60-1187.30) days. The 1-, 3-, and 5-year survival rates were 0.93, 0.71, and 0.65, respectively. The proportion of cured patients was 65.2%. The SIMEX method did not change the effect of LNR substantially on cure fraction as compared with the naive method when the variance of measurement error was 0.04 and 0.80. The CS method changed the effect of LNR on cure fraction even when the variance of measurement error was 0.04. Conclusion: The best method to assess the effect of LNR on cure fraction was the naive method, and the CS method was not deemed to be a valid method to correct the measurement error in LNR. [GMJ.2019;8:e1413]
Is Induction of Anomalies in Lymphocytes of the Residents of High Background Radiation Areas Associated with Increased Cancer Risk?
Authors: Mortazavi S M J , Mortazavi Gh , Mortazavi S A R , Paknahad M
Published: July 2019

Man has been exposed to different levels of natural background radiation since the creation of human life. There are inhabited areas around the world with extraordinary levels of natural background radiation. The level of natural radiation in these areas is up to two orders of magnitude higher than other places. Areas such as Yangjiang, China; Guarapari, Brazil; and Kerala, India are among the areas with high levels of natural radiation. Ramsar a coastal city in North Iran has some inhabited areas with the highest known levels of background radiation around the world. People who live in high background radiation areas (HBRAs) such as Ramsar do not record any detrimental biological effects. While some cytogenetic studies conducted in HBRAs have shown increased frequencies of unstable chromosome aberration, other investigations failed to find a significant difference. This short review is an attempt to verify if induction of chromosomal anomalies in the lymphocytes of the residents of high background radiation areas is associated with increased cancer risk.
Molecular Modelling and Evaluation of Hidden Information in ABCB11 Gene Mutations
Authors: Zarenezhad M , Dehghani S M , Ejtehadi F , Fattahi M R , Mortazavi M , Tabei S M B
Published: July 2019

Background: Cholestatic disorders are divided in the extra and intra-hepatic that created due to the severe liver diseases. ABCB11 encodes the bile salt export pump and this gene is mutated in several forms of intrahepatic cholestasis. So far, some molecular features of this gene was studies.Objective: Using a developed web server, we identified high number of rare codons in this gene, and four cases were related to BSEP-deficient patients which can be used for drug design.Material and Methods: By in-silico modelling of ABCB11, some of rare codons in different locations of ATP8b1 gene were identified and evaluated. Using several web servers a number of mutations that converted non-rare codons to rare codon in these patients were identified.Results: Some of these rare Codons were located at special positions by mutation of which, the new side chains do not seem suitable for protein structure and function. Furthermore, this mutation changed the protein folding rate that may have a critical role in proper folding. Thus, primary change of these codons contributes to BSEP deficiency.Conclusion: This work is a comprehensive analysis of rare codons of ABCB11 and assessment of a number of these rare codon in protein levels. Rare codons evaluation can enhance our understanding of ABCB11 structural protein of ABCB11, and help us to develop mutation-specific therapies in design of new drugs.
Resurrection and God’s Kingship in Tobit 13
Authors: Balla Ibolya
Published: July 2019

Tob 13:2 is found in the context of the hymn of praise of Tobit in Tobit 13. The chapter contains a Zion Song in 13:9-18 addressed to Jerusalem, similar to those found especially in Ap Zion (11QPsa XXII 1-15]) and Bar 4:30-5:9. The latter two do not have the idea of resurrection that appears in Tob 13:2, which in its immediate context (v. 1-8) is closely connected with 13:9-18. The paper aims at providing an overview of Tobit 13 in the context of the book and in relation to Ap Zion (11QPsa XXII 1-15) and Bar 4:30–5:9, while summing up the most important differences of the three Zion songs and attempting to explain the presence of the idea of resurrection in Tobit 13. The main arguments are as follows: the appearance of the concept of resurrection in relation to that of God’s kingship in proximity to a Zion song has to do – among others – with the characteristic content of Tobit’s and his family’s storyline in Tobit 1–12 and with the concern to combine notions of national and personal fate. The study refers to some of the scriptural influences on Tobit 13 and their significance, and treats the questions of the author’s view on God’s kingship, authority and on retribution at a national and individual level.
Why Paul Was Not Wrong in Quoting Hosea 13:14
Authors: Popko Łukasz
Published: July 2019

In 1 Cor 15:54-55, Paul quotes Isa 25:8 and Hos 13:14. A significant distance between these citations and the corresponding MT and LXX has been often explained as Paul’s intervention. The present article discusses the Hebrew original and compares the citations from 1 Cor 15 with other ancient translations. The polyvalence of the original source, semantic shifts due to the target languages, and accretion of meaning in the transmission process explain Paul’s text without a need of charging him of pia fraus. In the end, we try to deduce from this case study some elements of Paul's hermeneutics.
Resurrection in 1 Peter
Authors: Towner Philip H
Published: July 2019

This study observes the literary role of the language of "resurrection" in developing the message of 1 Peter.  The term itself goes mainly unexplained, and must be understood as part of the "retranslation" process in which the author is engaged--a process by which a dominant Roman political ideology is challenged as believers are encouraged to "rewrite" their lives in terms of experiencing the sufferings as a "normal" dimension of Christian existence.
Roman Bartnicki, Jezus w drodze do śmierci i zmartwychwstania. Komentarz do Ewangelii Marka 8,27-16,20, I, Mk 8,27-13,37 (Warszawa: Instytut Papieża Jana Pawła II 2018)
Authors: Rosik Mariusz
Published: July 2019

Book Review: Roman Bartnicki, Jezus w drodze do śmierci i zmartwychwstania. Komentarz do Ewangelii Marka 8,27-16,20, I, Mk 8,27-13,37 (Warszawa: Instytut Papieża Jana Pawła II 2018) (Mariusz Rosik)
Influence of indium and hydrogen co-doping on optical and electrical properties of zinc oxide thin films deposited by DC magnetron sputtering
Authors: Truong Nguyen Huu , Nguyen Tinh Van , Pham Tuan Anh Thanh , Hoang Dung Van , Vu Hung Minh , Nguyen Hoi Cong , Phan Thang Bach , Tran Vinh Cao
Published: July 2019

Introduction: ZnO-based thin films, known as potential transparent-conducting oxides (TCO), have still attracted much attention in applications for good-performance electrodes and inner layers in solar cells. Recently, the research tendency has focused on improving carrier mobility rather than carrier concentration to enhance performance and response speed of TCO thin films. In this work, Indium, and Hydrogen co-doped ZnO (HIZO) thin films were deposited by using DC magnetron sputtering technique in hydrogen-plasma atmosphere.

Methods: Indium-doped ZnO ceramics were used as sputtering targets, in which, Indium content varied from 0.07 to 1.0 at.%. The electrical, optical, structural and surface morphological properties of the as-deposited films were investigated by using Hall effect-based measurement, UV-Vis spectra, X-ray diffraction (XRD) and fieldemission scanning electron microscopy (FE-SEM), respectively.

Results: As a result, the HIZO films sputtered from the 0.1 at.% In-doped ZnO target and at H2/(H2+Ar) ratio of 3.5% exhibit high electron mobility (47 cm2/Vs), the lowest resistivity (4.9x10-4 Ω.cm) and sheet resistance (4.7 Ω/sq.), simultaneously, high average transmittance (>80%) in the visible – near IR spectrum regions.

Conclusion: Based on these results, the HIZO films are considered as potential TCO thin films that can be well-used as transparent electrodes in solar cells.
The Role of HCV E2 Protein Glycosylation in Functioning of Virus Envelope Proteins in Insect and Mammalian Cells
Authors: Orlova O. V. , Drutsa V. L. , Spirin P. V. , Ivanov A. V. , Prasolov V. S. , Rubtsov P. M. , Kochetkov S. N. , Beljelarskaya S. N.
Published: July 2019

The hepatitis C virus (HCV) envelope proteins E1 and E2, being virion components, are involved in the formation of infectious particles in infected cells. The detailed structure of the infectious particle of HCV remains poorly understood. Moreover, the virion assembly and release of virions by the cell are the least understood processes. It is believed that virion properties depend on glycosylation of the virus envelope proteins in a cell, while glycansat several glycosylation sites of these proteins play a pivotal role in protein functioning and the HCV life cycle. N-glycans of glycoproteins can influence viral particle formation, virus binding to cell surface, and HCV pathogenesis. We studied the effect of glycans on the folding ofthe E2 glycoprotein, formation of functional glycoprotein complexes and virus particles in insect and mammalian cells. In order to investigate these processes, point mutations of the N-glycosylation sites of HCV protein E2 (genotype 1b strain 274933RU) were generated and the mutant proteins were further analyzed in the baculovirus expression system. Elimination of the single glycosylation sites of the E2 glycoprotein, except for the N6 site, did not affect its synthesis efficiency in Sf9 insect cells, while the electrophoretic mobility of mutant proteins increased in proportion to the decrease in the number of glycosylation sites. The level of synthesis of HCV glycoprotein E2 in human HEK293T cells depended on the presence of glycans at the N1 and N8 glycosylation sites in contrast to Sf9 cells. At the same time, elimination of glycans at the N1, N2, and N10 sites led to the accumulation of unproductive E1E2 dimers as aggregates and productive assembly suppression of virus-like particles both in insect and mammalian cells. In addition, elimination of single glycosylation sites of HCV E2 had no impact on the RNA synthesis of structural proteins and formation of virus-like particles in insect and mammalian cells.
The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities
Authors: Povarnina P. Yu. , Yarkov S. A. , Gudasheva T. A. , Yarkova M. A. , Seredenin S. B.
Published: July 2019

The translocator protein (TSPO) promotes the translocation of cholesterol to the inner mitochondrial membrane and mediates steroid formation. In this study, we first report on a biological evaluation of the dipeptide GD-23 (N-carbobenzoxy-L tryptophanyl-L isoleucine amide), a structural analogue of Alpidem, the principal TSPO ligand. We show that GD-23 in a dose range of 0.05 to 0.5 mg/kg (i.p.) exhibits anxiolytic activity in the elevated plus maze test and nootropic activity in the object recognition test in scopolamine-induced amnesia in rodents. It was shown that GD-23 did not affect spontaneous locomotor activity, holding promise as a nonsedative anxiolytic agent. The anxiolytic and nootropic activities of GD-23 were abrogated by the TSPO specific ligand PK11195, which thus suggests a role for TSPO in mediating the pharmacological activity of GD-23.
PARP1 Inhibitors: Antitumor Drug Design
Authors: Malyuchenko N. V. , Kotova E. Yu. , Kulaeva O. I. , Kirpichnikov M. P. , Studitskiy V. M
Published: July 2019

The poly (ADP-ribose) polymerase 1 (PARP1) enzyme is one of the promising molecular targets for the discovery of antitumor drugs. PARP1 is a common nuclear protein (1-2 million molecules per cell) serving as a sensor for DNA strand breaks. Increased PARP1 expression is sometimes observed in melanomas, breast cancer, lung cancer, and other neoplastic diseases. The PARP1 expression level is a prognostic indicator and is associated with a poor survival prognosis. There is evidence that high PARP1 expression and treatment-resistance of tumors are correlated. PARP1 inhibitors are promising antitumor agents, since they act as chemo- and radiosensitizers in the conventional therapy of malignant tumors. Furthermore, PARP1 inhibitors can be used as independent, effective drugs against tumors with broken DNA repair mechanisms. Currently, third-generation PARP1 inhibitors are being developed, many of which are undergoing Phase II clinical trials. In this review, we focus on the properties and features of the PARP1 inhibitors identified in preclinical and clinical trials. We also describe some problems associated with the application of PARP1 inhibitors. The possibility of developing new PARP1 inhibitors aimed at DNA binding and transcriptional activity rather than the catalytic domain of the protein is discussed.
中学语文古典诗歌教学中“以乐写哀”手法例析
Authors: 郭 伟琦
Published: July 2019

“以乐写哀”是中学古典诗歌鉴赏教学中经常会碰到的艺术手法之一,是重点同时也是难点知识。通过对我国中学语文古典诗词教学现阶段的情况进行总结,不难发现,有很多教师在开展教学时对于“以乐写哀”手法缺乏系统讲解与剖析,这就让很多学生对于“以乐写哀”手法一知半解,在学习相关的文学作品时不能够精准的抓住作者的创作情绪。而很多学生在学习“以乐写哀”相关文学作品时也存在着诸多问题,有的学生由于缺乏人生阅历或是对于古代文学作品的学习能力较差等等原因,常常出现错误理解作者情绪,盲目解析文学作品的情况,这也与“以乐写哀”手法在中学语文课堂上教学成果较差有着很大的关系。本文试以教材所选课文《泊船瓜洲》《蜀相》《长恨歌》《窦娥冤》《姜斋诗话》等重点篇目为例,简析了该手法在诗文中是如何使用的及其效果。
立德树人，加强中小学人文教育
Authors: 苏 文学 , 李 秋云
Published: July 2019

人文教育是中小学教育的重要组成部分,目前不少学校仍是重视应试教育而轻视人文教育,人文教育中存在问题较多,如：课程缺失,流于表面,形式单一等,学术界关于中小学人文教育的研究也相对较少。本文从学校教育、家庭教育和社会教育等方面来阐述加强中小学人文教育的可行途径。
Valoración sociocultural del patrimonio construido: análisis de conjuntos habitacionales colectivos de la ciudad de Valparaíso, Chile
Authors: Larenas Salas Jorge , Fuster Farfán Xenia
Published: July 2019

Este artículo busca contribuir a la comprensión de algunos conceptos clave en los procesos de declaratoria patrimonial, sobre todo cuando se trata de inmuebles correspondientes a conjuntos modernos de vivienda colectiva, y más específicamente desde las coordenadas de la valoración sociocultural, es decir, poniendo énfasis en la perspectiva de las comunidades que habitan en dichos conjuntos. El tema se aborda a través del caso de la vivienda colectiva en la ciudad de Valparaíso. El enfoque metodológico integró una doble perspectiva: en una primera fase se trabajó cualitativamente mediante entrevistas individuales y colectivas con el objeto de explorar e identificar aquellos atributos patrimoniales que son reconocidos por los habitantes de los conjuntos de vivienda colectiva y, en una segunda fase, se desplegó un diseño de corte cuantitativo a través de la aplicación de un instrumento estandarizado que permitió un tratamiento descriptivo de tales atributos. Sobre la base de esto, se identificaron aquellos que son más valorados por la comunidad, tales como el diseño, calidad, particularidad y localización de las viviendas. El artículo plantea algunas conclusiones en torno a la pertinencia de relevar la percepción y prácticas de los habitantes en el abordaje, desde una perspectiva patrimonial, de los conjuntos de vivienda colectiva. En este sentido, se evidencia una tensión importante entre las dimensiones materiales e inmateriales del patrimonio, estableciéndose la pertinencia de considerar mecanismos —como los que este trabajo propone— de evaluación del patrimonio que incorporen la perspectiva de los habitantes.
Increasing the level of economic security of Russia in the conditions of digital transformation of the economy
Authors:   Market Economy Institute of RAS, Zoidov Zafar K.
Published: July 2019

The monograph examines the problems that determine the development and improvement of mechanisms to ensure economic security of Russia in the context of building a digital economy. A system-structural approach is formulated to develop a new paradigm of increasing economic security of Russia in the formation of the infrastructure of the digital economy in order to restore the national scientific, technical and industrial sovereignty of Russia in the field of digital technologies. The problems are analyzed and the ways of overcoming systemic imbalances in the processes of building a reference digital infrastructure as a threat to Russia's economic security are highlighted, taking into account the global trends of innovation and digital transformation. The monograph is intended for managers and specialists of public administration and corporate management, researchers, postgraduates and students.
The Sequence of Care – Do New Methods Warrant a Shift from the Standard Abc to a Cabc Approach?
Authors: Whitfield Steve
Published: July 2019

Adaptions and change are vital to the development of pre-hospital care. Emerging evidence-based practices ensure best patient care. The A irway, Breathing, Circulation (ABC) sequence of care in pre-hospital environment is ignoring a vital step in trauma support. This commentary provides an evidence-based discussion and explores the appropriateness of the current ABC sequence of care.
The subjective voice and hybrid documentary filmmaking strategies
Authors: Daniels Jill
Published: July 2019

In this case study Jill Daniels references several of her recent experimental documentary films that mediate memory, place and subjectivities: Not Reconciled (2009); The Border Crossing (2011); My Private Life (2013); My Private Life II (2015) and Journey to the South (2017). She proposes the notion that film communicates in a sensory mode that may defy written theorisation or interpretation, with a rigor and precision that is quite separate to that of written language, but that nevertheless films, like written language, may add to knowledge. She argues that film theory is essential to enable the filmmaker to raise their work above the narrow framework of craft. She interrogates the notion that experimentation in documentary films may avoid perceived constraints of certainty, evidence and veracity. She notes that as a practice researcher within the academy she has freedom to experiment, which has brought considerable benefits to her practice.
The methodology behind digital papers
Authors: Gough-Brady Catherine
Published: July 2019

In 2015 Ross Gibson wrote about the need in the academy for “linguistic explication” of the artwork and creative process, in particular to encourage debate on knowledge that arises from the work. I began my creative practice PhD after spending twenty years as a successful documentary practitioner. When it was time to start writing about my research and the new knowledge, instead of using text I turned to the audiovisual medium as my method of communication. I created “Filming” (2017), which combines the theory-rich mode of academic papers with the audio-visual form of my art, documentary. I called it a “digital paper”. The digital paper form has become an integral part of my PhD. This hybrid creative practice uses my artform medium as my method of communicating Gibson’s “linguistic explication”, rather than using text alone. This report will locate the digital paper within my PhD practice.
An Analysis of Imposed Charity (Iltizām-e-Taṣadduq) in Islamic Banking
Authors: Aslam Dr. Atif
Published: July 2019

There are many new alternatives adopted by Islamic banks for the interest-based transactions of conventional banks. One of them is Imposed Charity (Iltizām-e-Taṣadduq) for the monetary penalty on late payment. But it is argued by the Sharia’h scholars that it is nothing but a forbidden monetary penalty. This thesis describes the need and mechanism of the imposed charity and puts forward the arguments of the scholars on it with the answers from Banking practitioners. This will help us to weigh different stances on the subject.
Producción de energía eólica en Ecuador
Authors: Párraga Palacios Ángel Germán , Intriago Rodríguez Sney Alexander , Velasco Fuentes. Evelyn Denisse , Cedeño Quinto Victoria Mariuxi , Cedeño Quinto Victoria Mariuxi , Murillo Párraga Néstor Lizardo , Zambrano Gavilanes Freddy Eli
Published: July 2019

Esta investigación tuvo como objetivo determinar la producción de energía eólica en el Ecuador, de acuerdo a la generación de la energía eólica producida en el estado ecuatoriano, permite conocer el nivel de seguridad para el suministro de energía eléctrica; por medio que se garantiza el abastecimiento del consumo para las diferentes actividades requeridas por la sociedad. El desarrollo de la matriz eléctrica se basa en la accesibilidad a las diferentes fuentes, siempre y cuando se cuente con un adecuado nivel de disponibilidad del estado. Sin embargo, en cualquier país existen momentos, políticos, económicos y ambientales que determinan la manera tácita el nivel de seguridad energética. Mientras tanto las comunidades rurales sin acceso a la electricidad satisfacen sus necesidades de iluminación y comunicaciones sociales con fuentes alternativas. Todos los estudios han demostrado que los ingresos de los generadores de energía eólica disminuyen el costo en el mercado con el aumento de su despliegue; esta caída de valor se observa principalmente en los estados donde la principal fuente de energía es la térmica. Los modeladores de sistemas de energía requieren serie de tiempos de alta resolución de la producción de energía eólica, como su variable y la naturaleza impredecible planta desafíos cada vez mayores para el sistema de electricidad del mundo. El Ecuador y el continente requiere de soluciones para conservar sus recursos naturales agotable existente y una de ella es sustituir la producción de energía que actualmente se utiliza fuentes no renovables por las fuentes inagotables o renovables.
Talleres de escritura y su incidencia en la producción de textos descriptivos en inglés
Authors: Carmita Eulalia Rojas Castro , Mónica Alejandra Logroño Becerra , Paul Rolando Armas Pesantez , Ana Gabriela Reinoso Espinosa
Published: July 2019

El objetivo de la investigación, fue analizar la incidencia de los talleres de escritura en la producción de textos descriptivos en los estudiantes del Centro de Idiomas de la Escuela Superior Politécnica de Chimborazo, bajo los parámetros de: pre escritura, borrador, revisión, edición y corrección. Para lo cual, se aplicó un plan de intervención sobre la base de las deficiencias detectadas. La muestra estuvo conformada por 2 grupos de 41 estudiantes. Al grupo experimental se aplicó el plan de intervención; mientras que el grupo de control siguió el método tradicional. Cada grupo fue evaluado mediante un instrumento en dos momentos: al inicio y al final de la experimentación. Los resultados fueron tabulados, analizados y sometidos a una prueba estadística; la misma que permitió concluir que los talleres influyeron de manera significativa en la producción de textos descriptivos.
Efecto de la fertilización fosfatada en la fenología de tres variedades de alfalfas (Medicago sativa L.)
Authors: Oñate Viteri Wilson , Flores Mariazza Enrique
Published: July 2019

Se determinó el efecto de diferentes niveles de fertilización fosfatada en tres variedades de alfalfas introducidas en tres etapas fenológicas en el comportamiento agronómico.  El ensayo se realizó en la Estación Experimental Tunshi, ubicada en el cantón Riobamba, Provincia de Chimborazo, Ecuador. Los tratamientos que se utilizaron fueron las variedades de alfalfa como factor A (abunda verde, cuf-101 y sw-8210) y como factor B las dosis de fertilización (0, 50, 100 y 150 kg/P/ha). Las parcelas experimentales se distribuyeron bajo un diseño de bloques completamente al azar con arreglo en parcelas divididas y tres repeticiones; se realizó el análisis de varianza, comparación de medias según Tukey y el análisis de la regresión. Los resultados experimentales no registraron diferencias significativas (p>0.05) para la interacción A x .  Al analizar los factores principales en el factor A se observó que la relación hojas/tallo para la variedad abunda verde fue de 1.23 hojas/tallo, difiriendo significativamente (p < 0.05) de la variedad sw8210 que registró 1.12 hojas/tallo. Al analizar el factor B, la cobertura aérea alcanzó el 84.29% cuando se aplicó 150 kg/P/ha que difirió significativamente (p< 0.01) del tratamiento control (76.60%).  Además la utilización  de 150 kg/P/ha registró una cobertura basal de 29.41% que difirió estadísticamente (p< 0.01) del tratamiento control (25.74%). La relación hojas/tallo fue de 1.26 diferenciándose significativamente (p<0.01) del tratamiento testigo (1.11). En  relación a la producción de materia seca no se evidencio diferencias significativas entre variedades de alfalfa  y los niveles de fertilización fosfatada (P>0.05), realizando la época  de cosecha a los 110 días cuando las plantas presentaron más de cinco rebrotes ya que no hubo inducción a la floración. El análisis económico determinó un  benéfico/costo de $ 1.38 cuando se utilizó 150 kg/P/ha valor que difirió del  tratamiento control (P<0.01) con un beneficio/costo de $ 1.23.
Estudio estadístico de la educación vial en las Unidades Educativas de la Ciudad de Riobamba
Authors: Londo Yachambáy Fabián Patricio , Sánchez Salcán Narcisa de Jesús , Morales Noriega Margarita , Guerra Sarche Xavier Alejandro
Published: July 2019

El presente estudio de investigación se realizó a estudiantes de Bachillerato de las Unidades Educativas del cantón Riobamba, quienes son un punto vulnerable en el tema accidentabilidad, el objetivo de la investigación es analizar el conocimiento que tiene esta población en estudio sobre lo que es Educación Vial. Se aplicó un enfoque cuantitativo, los tipos de investigación utilizadas fueron bibliográfica y descriptiva, apoyada en los métodos inductivo-deductivo y analítico-sintético y deductivo; las técnicas utilizadas para recopilar información primaria corresponden a la encuesta aplicada a los estudiantes de bachillerato. Los resultado de la investigación evidenciaron que dicha población es un ente que tiene bajos conocimientos de lo que es Educación Vial, es así que no existe una capacitación adecuada en los centros educativos sobre este tema tan vital, así como un desinterés por mejorar esta algia situación, debilidades con una falta de señalética adecuada. Para superar dichas falencias, es imperiosa la necesidad de implementar una asignatura sobre educación vial en los diferentes niveles de educación diseñar estrategias comunicacionales, con el propósito de concientizar a toda la ciudadanía sobre el tema de Primero el Peatón, con la finalidad de generar identidad y proyectar una imagen favorable y así disminuir las elevadas tasas de accidentabilidad que se tiene en el país.
Trastornos específicos del lenguaje en el desarrollo del habla del Idioma inglés.
Authors: Suárez Cabrera Sonia Marcela , Escudero Orozco Gloria Isabel , Cabezas Arévalo Leonardo Efraín
Published: July 2019

Este estudio analizó los principales trastornos del lenguaje que se presentan en el desarrollo del habla del idioma inglés. Se indagaron sobre deterioros del lenguaje y del habla, la fluidez, logro social siendo estos los más comunes. Para la obtención de información se realizó una investigación cuali-cuantitativa, de campo tipo aplicativa. Se trabajó con los estudiantes de Segundo Semestre de la Carrera Cultura Física de la Universidad Nacional de Chimborazo. Los resultados mostraron que el 60% de los estudiantes presentaron dificultades en su desarrollo del habla del idioma inglés, el 66% consideraron que aplicar mayor cantidad de actividades lingüísticas relacionadas con expresión oral ayudó a mejorar las habilidades productivas del habla, el 26% de los estudiantes tuvieron dificultades lingüísticas. Del total de la muestra, el 40% de estudiantes persistió con esta dificultad presentando trastornos específicos en el desarrollo del lenguaje. Finalmente, se concluye que la aplicación de estrategias terapéuticas productivas fue efectiva, ya que los estudiantes que mostraban desordenes, mejoraron su habilidad de hablar.
IMPLEMENTATION OF FACILITIES AND INFRASTRUCTURE MANAGEMENT IN PUBLIC ELEMENTARY SCHOOLS
Authors: Marmoah Sri , Adela Dhea , Fauziah Muna
Published: July 2019

This study utilized to analyze the implementation of management of school facilities and infrastructure. This type of research is descriptive qualitative conducted in Public Elementary School of 01 Bakipandeyan. Data collection techniques in this study include in-depth interviews (Principals, treasurers, teachers, and school committees) and documentation studies. The validity of the data gathered in this study was technical triangulation (in-depth interviews and documentation) and sources (Principals, teachers, and school committees). Data analysis techniques gather interactive analysis with stages: data reduction, data presentation, and verification. The results showed that the implementation of facilities and infrastructure management in Public Elementary School of 01 Bakipandeyan was carried out through three stages, namely: (1) procurement of facilities (2) utilization and (3) maintenance of facilities and infrastructure. Researchers suggest that schools be better at managing school facilities and infrastructure and looking for specialized workers to manage school facilities and infrastructure.
KOMPETENSI MANAJERIAL KONSELOR PADA LAYANAN KONSELING KELOMPOK
Authors: Riswanto Dody
Published: July 2019

The purpose of this study was to determine the managerial ability of the counselor in implementing group counseling at school. The research method used is qualitative, data analysis used is drawing conclusions based on Lawrence's theory. The results of the research and discussion are conflict, resistance, confrontation and imbalance of group members as the main problems in group dynamics, the managerial ability of the counselor in organizing, leading, directing and organizing all group members to be successful indicators of group counseling success.
MANAJEMEN STRATEGI DALAM MENINGKATKAN MUTU PELAYANAN KEPEGAWAIAN
Authors: Hefniy Hefniy , Fairus Refi Najma
Published: July 2019

Strategy Management in improving the quality of staffing services in the Probolinggo District Education Office. The purpose of this article was to study the management of strategies carried out by the Education Office of Probolinggo District specifically service personnel and the quality of staffing services from the implementation of the management strategies in the Probolinggo District Education Office. This study uses qualitative methods with a type of case study research. The data analysis used is the Interactive analysis model of Miles and Huberman. The results is showed that the management strategy carried out by the Probolinggo District Education Office was also applied to staffing services guided by the Provincial RPJP and Probolinggo District RPJMD using a strategic planning process, implementing strategies and evaluation strategies. And the quality of the Probolinggo District Education Office staffing services after the strategy management has been fairly good with reference to the fulfillment of five service standards.
TANTANGAN KARAKTER DI ERA REVOLUSI INDUSTRI 4.0 DALAM MEMBENTUK KEPRIBADIAN MUSLIM
Authors: Pratama Dian Arif Noor
Published: July 2019

Indonesia as a nation-state and ethnic group that the majority is Muslim, has many of heritage value that can shape its personality into a superior character. Seeing the phenomenon of the industrial era 4.0 as if forgetting the character values as human identity which inevitably lost the divine values. To build the nation's next generation with good character is the responsibility of all lines of life, because education is truly our shared responsibility, for sure this is not an easy matter, therefore awareness of all parties is needed that character education is very important to be implemented. Although all parties are responsible for character education, but the family is the central pillar as the first means for instilling character education so that a solid Muslim personality is shaped. Family failure in instilling character values towards a child will complicate other institutions outside of the family (including schools) in an effort to improve the character of the child. Transfer of habituation based values is an alternative process that must be carried out continuously, so that the formation of children's  character individually, restoring divine values in Muslim personality. thus it will form socio-culture in society and socio-cultural shape the country that has character.
SUPERVISI AKADEMIK : MENGURAI PROBLEMATIKA PROFESIONALISME GURU DI SEKOLAH
Authors: Munawar Munawar
Published: July 2019

This paper examines the principal's strategy in solving the problems of teacher professionalism through academic supervision. Academic supervision activities are a series of activities to help teachers explore and develop their competencies in order to manage learning activities well in order to achieve learning goals. This study is a literature review / research library where the data analysis is done through content analysis. The results of the study indicate that academic supervision activities carried out by the principal must begin with planning, implementation and evaluation with the principle of objectivity and continuous improvement. Through this, the professionalism of teachers in schools will be easily achieved and will be able to improve the quality of learning and the quality of educational institutions.