bluuebunny/crossref_metadata_2025 huggingface dataset:
Meningkatkan Pemahaman Masyarakat tentang Pentingnya Pendidikan di Dusun Karanganyar Kecamatan Sumbersuko Kabupaten Lumajang
Authors: Ulumuddin Ihya’ , A’yun Qurroti , Safa'ah Alfiatus , Firdausi Putri Nadiyatul , Lestari Rizki Dwi , Karomah Lailatul
Published: December 2024

RA Muslimat NU Nurul Hikmah Sumbersuko merupakan sebuah lembaga pendidikan yang berada di Dusun Krajan, Desa Sumbersuko. Sudah dua tahun dekorasi dan hiasan ruangan di RA Muslimat NU Nurul Hikmah Sumbersuko belum diganti atau diperbaiki, sehingga banyak yang rusak, rapuh, dan kusam. Suasana ruang kelas demikian tidak cocok dengan anak usia dini yang sangat peka terhadap warna mencolok. Bagi anak kecil, selain sebagai hiasan yang menarik, hiasan dinding juga difungsikan sebagai media belajar untuk lebih mengenal lingkungan sekitar. Metode yang digunakan dalam penelitian ini adalah
Peningkatkan Nilai Pendidikan dan Daya Tarik Wisata Sungai Ilmu Tumpak Selo Desa Petahunan Lumajang
Authors: Ibad Taqwa Nur , Anugrah Yuli Dwi Yusrani , Masyhuri Muhammad , Maya Iklilah Arum , Mujib Abdul , Qomaria Lailatul
Published: December 2024

Pendidikan dan wisata merupakan dua aspek penting dalam menggali potensi suatu wilayah. Sungai ilmu Tumpak Selo memiliki peran yang signifikan dalam memadukan dua aspek tersebut. Penelitian ini bertujuan untuk meningkatkan nilai-nilai pendidikan dan daya tarik wisata melalui Sungai Ilmu Tumpak Selo. Hasil penelitian menunjukkan bahwa sungai ilmu, selain sebagai sumber air juga memiliki makna simbolis sebagai sungai pengetahuan yang kaya akan nilai pendidikan. Dengan memanfaatkan sumber daya alam sekitar program pendidikan yang terkait dengan lingkungan, keberlanjutan dan keanekaragaman hayati dapat dikembangkan. Selain nilai pendidikan, kawasan sekitar Tumpak Selo juga memiliki daya tarik wisata yang menarik. Keindahan alam, air yang jernih dan bersih ini memberikan pengalaman yang baik untuk para pengunjung. Pengembangan infrastruktur pariwisata yang berkelanjutan dapat meningkatkan daya tarik wisata Tumpak Selo sambil menjaga kelestarian lingkungan. Dengan menyelaraskan pendidikan dan wisata melalui sungai ilmu, dapat diciptakan model pengelolaan yang holistik. Peningkatan kesadaran masyrakat terhadap pentingnya pendidikan dan pelestarian alam dapat menjadi modal utama dalam mencapai tujuan ini. Diharapkan hasil penelitian ini dapat memberikan kontribusi pada peningkatan nilai- nilai pendidikan dan daya tarik wisata melalui sungai ilmu, khususnya Tumpak Selo
Literary Life In The First Republic Of Armenia (1918–1920)
Authors: Gasparyan Davit , Vardanyan∗ Gurgen
Published: December 2024

The article presents the literary life in the First Republic of Armenia. It was preceded by the Armenian Genocide carried out by Ottoman Turkey in 1915, as a result of which we lost the golden generation of Western Armenian literature: Grigor Zohrap, Ruben Zardaryan, Daniel Varuzhan, Siamanto, Ruben Sevak and others. Abroad, during this period, great Eastern Armenian writers continued to write: Hovh. Tumanyan, Av. Isahakyan, A. Shirvanzade, Nar-Dos, V. Teryan and others, who sought to contribute to the revival of the motherland. Literary figures in Armenia were taking steps to regulate the literary life of the republic. In turn, the leadership of the First Republic paid serious attention to the publication of works by Armenian authors.
An Episode From The History Of The Armenian State And Church Relations In Cilicia (1175-1187)
Authors: Zhamkochyan Nelli
Published: December 2024

This study thoroughly discusses the relations between the State and the Church during the period of the ruler of Cilicia, Ruben III (1175-1187). The research highlights Armenian-Byzantine ecclesiastical relations, focusing on the recent efforts made by Byzantium in unifying the churches, as well as the circumstances of the famous Hromkla (modern Rumkale) Church Council. Different views on the date of convening the assembly are examined, as well as the established decisions. The article introduces the Armenian-Catholic church-political relations and procedure, and presents the demands of the Roman Catholic Church to the Armenian Apostolic Holy Church. It focuses on the details of the cooperation between the Roman Catholic Church and the Armenian state of Cilicia on these important issues. In the framework of this study, the issues around the Armenian Churches in the Armenian Community of Egypt are presented. Are given details about the joint efforts of the Armenian Government and the Church of Cilicia in the process of preserving the Churches. In the article we have presented the circumstances of how the Ayyubid Sultan Salah ad-Din had tried to take the Armenian Churches of Egypt from the Armenians and give them to the Copts, but as a result of the joint efforts and discussions of the Armenian leadership and the Catholicosate of Rumkale, it was possible to return them to their rightful owner.
The Armenian Voluntary Movement In The Russian Collection Of Documents
Authors: Sahakyan Ruben
Published: December 2024

The fact that Ottoman Empire was in a hostile group in the World War I raised hopes among almost all Armenians that the Entente powers would defeat the enemy and Western Armenia would eventually gain autonomy under Russian patronage. The issue of Armenian reforms reopened by the Russian government on the eve of the war inspired such hope. The Russian side promised to make reforms, even give autonomy to Western Armenia, if the Armenians organize volunteer militia units. That was the main reason why the Armenians quickly responded to the call of the Russian official authorities to organize volunteer groups. It is evident that there were people in the Armenian national parties, political, religious and social circles who were categorically against the Armenian volunteer movement.
Challenges in the management of visual and tactile hallucinations in elderly people
Authors: Huang Si-Sheng
Published: December 2024

This letter provides a concise review of the pertinent literature on visual and tactile hallucinations in elderly patients. The discussion addresses differential diagnoses and potential underlying mechanisms, as well as the psychopathology associated with tactile hallucinations, and emphasizes the necessity for investigation into the possibility of coexisting delusional infestation (parasitosis). These symptoms frequently manifest in patients with primary psychotic disorders, organic mental disorders, and substance use disorders. The proposed pathophysiological mechanisms may involve dopaminergic imbalances and dysfunction of the striatal dopamine transporter.
Integration with revenue management for revenue recognition through subscriptions workflows
Authors:   Engineer (Product), Cardinal Health, Kalpinagarajarao Gopikrishna
Published: December 2024

In today’s subscription-driven economy, businesses rely heavily on accurate and automated revenue management
systems to ensure compliance, efficiency, and scalability. Integrating revenue management with subscription
workflows involves handling complex processes such as billing, payment allocation, and revenue recognition.
Middleware tools like MuleSoft, Service-Oriented Architecture (SOA), and Boomi play a pivotal role in
streamlining these integrations, enabling seamless data flow and ensuring compliance with standards like ASC 606
and IFRS 15.
Integrating revenue management with subscription workflows is critical for accurate revenue recognition,
especially in subscription-based business models. In such setups, the integration ensures compliance with
accounting standards like ASC 606 or IFRS 15, while also streamlining financial processes.
Keywords: SOA, Middleware, Subscription management, Revenue Management, BOOMI,
Use of Python in Data science, Data Integration and Data Engineer
Authors: Srivastava Ankit
Published: December 2024

Python is a popular language for tasks like data cleaning, transformation, and machine learning model development
in data science, data integration, and data engineering because of its adaptability, user-friendliness, and vast library
of tools that make it easier to manipulate, analyze, visualize, and create pipelines. These tools also enable efficient
data processing and extraction from a variety of sources.
Keywords: Python, Data Integration, Data Science, AI
AI-Driven Approach to Advancing Backup Strategies and Optimizing Storage Solutions
Authors: Mehra Taresh
Published: December 2024

The rapid growth of data, coupled with the increasing complexity of cybersecurity threats, has necessitated
innovative approaches to data backup and storage. This paper explores the application of Artificial Intelligence (AI)
in selecting backup methods and storage devices, aiming to enhance efficiency, reduce costs, and ensure data
integrity. Through data-driven strategies, AI can dynamically classify, prioritize, and manage backups while
recommending optimal storage solutions tailored to specific organizational needs.

Keywords

AI in backup, data storage optimization, data classification, dynamic scheduling, hybrid backup
Transforming Supply Chain Management with Big Data and IoT Innovations
Authors: Surkunde Arpita Bhausaheb , Jarad Dr. Rajendra , Yadav Dr. Mahendra , Suryavanshi Dr. Praveen , Bhavsar Prof. Dhanajay , Moholkar Prof. Nilambari
Published: December 2024

The integration of Big Data and the Internet of
Things (IoT) is revolutionizing supply chain
management, enabling enhanced efficiency,
transparency, and adaptability in a rapidly
changing global landscape. Big Data analytics
empowers organizations to process and interpret
vast datasets, delivering actionable insights for
demand forecasting, inventory optimization, and
risk mitigation. Concurrently, IoT devices facilitate
real-time monitoring, tracking, and seamless
communication across the supply chain, bridging
the gap between physical and digital operations.
This paper examines the transformative potential
of combining Big Data and IoT in supply chain
management, focusing on their synergistic
applications and benefits. It explores how these
technologies enable predictive analytics, improve
operational resilience, and foster sustainable
practices. Key challenges, such as data security,
system integration, and the need for skilled
personnel, are also discussed. The findings
highlight the strategic importance of adopting Big
Data and IoT to create smarter, more responsive
supply chains capable of thriving in dynamic
market conditions. This research provides a
roadmap for organizations aiming to leverage these
innovations to gain a competitive edge while
addressing the complexities of digital
transformation.
I. Keywords: Big Data, Internet of Things (IoT),
Supply Chain Management, predictive analytics,
Innovations.
REAL TIME SPORT ANALYSIS
Authors: Deepa Dr .M , R Kishore , S Vibin , A Abhishek
Published: December 2024

The integration of Artificial Intelligence (AI) in sports has revolutionized how games are analyzed and
strategies are formulated. This project focuses on developing a real-time sports analysis system powered by AI to
provide comprehensive insights into player performance, team dynamics, and game strategy.
The system leverages computer vision techniques to process live video feeds, extracting key metrics such as player
positions, movements, and interactions on the field. Deep learning models, trained on historical game data, are used
for predictive analytics, enabling the identification of patterns and forecasting potential outcomes. Natural Language
Processing (NLP) is incorporated to generate instant commentary and actionable insights for coaches, players, and
broadcasters.
Key features include player tracking, automated highlight generation, and tactical analysis. The system is designed
to function seamlessly across various sports, such as football, basketball, and cricket, with adaptable algorithms
tailored to the rules and dynamics of each game. Real-time processing is achieved using edge computing and
optimized AI models to minimize latency.
Index Terms: Artificial Intelligence (AI), Real-Time Analysis, Sports Analytics, Computer Vision, Deep Learning,
Player Tracking, Performance Metrics, Predictive Analytics, Tactical Analysis
Review Paper on Keystroke Dynamics
Authors:   Lecturer, VPM’s CoE, Thane., Gawade Sujata Prashant
Published: December 2024

In Today’s Digital world need of
authentication is not limited to password and PIN. It
requires a high level of security which can be achieved
by Keystroke biometrics. This review paper attempts to
catch the imposter even if one carries login details of
genuine user. The paper tries to review the keystroke
methods and draw a common conclusion. Adding
keystroke mechanism with existing authentication
system helps to enhance the security.
Keywords: Keystroke Biometrics, Network Security,
Password Security and Password Strengthening.
Role of Robotic Systems in Minimally Invasive Surgery: Benefits, Risks, and Future Directions
Authors:   R&D Engineer – Controls and Robotics, Systems Engineering, Pasupuleti Shashank
Published: December 2024

Robotic systems have significantly transformed the landscape of minimally invasive surgery, offering enhanced
precision, reduced recovery times, and improved patient outcomes. These systems have evolved from simple
mechanical tools to sophisticated platforms integrating advanced control algorithms and real-time feedback
mechanisms. This paper provides a comprehensive overview of the role of robotic systems in minimally invasive
surgery, exploring the various benefits, inherent risks, and the challenges associated with their adoption and
development. We examine the technical aspects of robotic control systems, such as kinematics, force control, and
haptic feedback, which enable greater surgical accuracy. Despite these advantages, challenges such as system
complexity, high costs, and ethical concerns remain significant barriers to widespread adoption. The future of
robotic surgery lies in overcoming these obstacles, with advancements in system miniaturization and further
refinement of control systems poised to enhance the efficacy and accessibility of robotic platforms. This paper
explores the role of robotic systems in minimally invasive surgery, focusing on three key areas: bronchoscopy and
ureteroscopy. By reviewing the benefits, risks, case studies, and future directions of these technologies, the paper
seeks to provide an in-depth understanding of how robotic systems are shaping the future of surgery.

Key words: Robotic Surgery, Minimally Invasive Surgery, Robotic Control Systems, Surgical Precision, PID
Control, Kinematics, Inverse Kinematics, Forward Kinematics, Dynamic Control, Force Control, Impedance
Control, Surgical Robotics, Haptic Feedback, Robotic Arm, Robotic Surgery Benefits, Robotic Surgery Risks,
Robot-Assisted Surgery, Surgeon Console, Real-Time Feedback, Surgical Training, Robotic System Development,
System Testing, Clinical Trials, Surgical Robot Performance, Robotics in Urology, Telepresence Surgery, Robotic
Surgery Cost, Robotic Surgery Future Directions.
Sodyum-iyon Pillerde Kullanılan MnFe-Bazlı Katotlarda Ni Etkisinin Araştırılması
Authors: Kalyoncuoğlu Burcu , Altın Serdar , Özgül Metin
Published: December 2024

P2-NaMnO2 tabakalı metal oksit katot malzemeleri şarj edilebilir piller için yüksek kapasiteli ve ucuz bir pil malzemesi olarak bilinmektedir. Ancak Na+ iyonlarının interkalasyonu sırasında oluşan “Jahn-Teller bozulması” uygulamalarda kısıtlamalara neden olmaktadır. Yapılan çeşitli katkılamalarla bu bozulmaların baskılandığına dair çalışmalar mevcuttur. Bu çalışmada, x=0-0.5 mol% aralığında değişen oranlarda Ni katkılama ile katı hal sentezi yöntemi ile Na0.67Mn0.5-xNixFe0.43Al0.07O2 kompozisyonlarında katot malzemesi tozları üretildi. Üretilen örneklerin mikro yapı incelemeleri için SEM, kristal yapı tayini için XRD ve bağ türlerinin tespiti için FTIR analizleri ile yapısal karakterizasyonları gerçekleştirildi. İncelenen örnekler arasında en düşük BET yüzey alanı katkısız kompozisyonda gözlemlenmiştir. Üretilen katotların elektrokimyasal analizleri için Na0.67Mn0.5-xNixFe0.43Al0.07O2/sodyum metali ile hazırlanan CR2032 düğme pil hücreleri kullanıldı. Oluşturulan hücrelerin CV, EIS ve kapasite ölçümleri oda sıcaklığında gerçekleştirildi. Hücrelerin en yüksek kapasitesi katkısız örneklerde C/3 ve C/20 hızlarında sırasıyla 172 mAh/g ve 203 mAh/g olarak bulundu. Ni'in Na0.67Mn0.5Fe0.43Al0.07O2 içindeki içeriğinin artmasıyla Na tabakaları arasındaki mesafenin azaldığı görülmüştür. Bu durumun kristal yapıdaki Mn ve onunla yer değiştiren Ni iyonlarının iyonik yarıçaplarındaki farklılıktan kaynaklandığı söylenebilir.
From Value to Value Co-Creation: A Historical Review
Authors:   PhD Student, Economics and Public Policy Laboratory (LSEPP), Ibn Tofail University Morocco, Reda LHARTI , Fatima CHAREF ,   Professor researcher, Economics and Public Policy Laboratory (LSEPP), Ibn Tofail University Morocco
Published: December 2024

This article explores the conceptual evolution of the notion of value throughout history, highlighting the various perspectives that have shaped the understanding of this concept. The analysis begins with the Greek philosophers of Antiquity and spans the centuries up to the 21st century, examining major shifts in the perception of value.
The first section of the article is devoted to a historical approach to value, tracing the contributions of Greek philosophers through to modern thinkers in the 21st century. It illustrates how the perception of value has evolved over time, transitioning from objective, intrinsic notions to more subjective and relational conceptions.
The second part of the article analyzes the concept of value creation, its processes, and the evolution towards value co-creation, exploring their fundamental principles and the elements that have been incorporated into these models.
Finally, the article discusses the results, emphasizing the key findings and tracing the origins and development of the concept of value throughout history.
Effects of Weed Control Treatments on Boro rice and Associated Weeds
Authors:   Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh, Ali Md. Akib , Islam Md. Shafiqul ,   Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh, Kabiraj Md. Sojib ,   Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh, Sarker Uttam Kumer ,   Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh, Zaman Farhana ,   Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh, Kumar Swapan ,   Paul Department of Agronomy, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
Published: December 2024

A study was conducted to examine how different rice varieties and weed management strategies impact the yield of Boro rice. The trail included two varieties viz. BRRI dhan28 and BRRI dhan29, and seven different weeding methods: no weeding, one hand weeding (HW) at 15 days after transplanting (DAT), two HW at 15 and 35 DAT, three HW at 15, 35 and 55 DAT, application of superhit 58 SL @ 0.2% (pre-emergence), application of livina 18 WP @1.5 g/L water (post-emergence) and rice residues 3 t ha-1. The study was structured using a Randomized Complete Block Design (RCBD) and replicated thrice. The findings exposed that ten families were represented by fifteen weed species that infested the experimental plots. Density and dry weight of weed was not notably affected by rice varieties. At 35 and 55 DAT, three HW at 15, 35 and 55 DAT produced the lowest weed density (0.83 m-2), (1.16 m-2) and weed dry weight (0.19 g), (0.33 g). In interaction, three HW at 15, 35 and 55 DAT recorded least weed density (0.66) and (1.00) at 35 and 55 DAT. BRRI dhan29 produced the maximum number of total tillers hill-1 (9.61), effective tillers hill-1 (9.00), panicle length (22.10 cm), grains panicle-1 (126.75), harvest index (47.09 %) and grain yield (4.71 t ha-1) compared to BRRI dhan28. Three HW at 15, 35 and 55 DAT resulted maximum number of total tillers hill-1 (10.50), effective tillers hill-1 (9.40), panicle length (22.16 cm), grains panicle-1 (118.56) and grain yield (5.39 t ha-1). BRRI dhan29 along with three HW at 15, 35 and 55 DAT recorded maximum grain yield (5.55 t ha-1). The study suggests that conducting three rounds of HW at 15, 35 and 55 DAT could be the most efficient method for both weed management and achieving a higher grain yield in Boro rice.
REFLECTION OF REALITY IN THE ASPECT OF ONTOLOGICAL CONCEPTS IN WORLD CINEMA
Authors:   Kazakh National Academy of Choreography, Aspandiyarkyzy G. , Chesnova O.A. ,   Sankt-Petersburg State Institute 30 of cinema and television
Published: December 2024

This article examines the ontological aspects of cinema,
beginning with the classical theories of André Bazin and extending
to contemporary studies on the impact of digital technologies on
the perception of reality in film. The primary focus is on the ability of
cinema to capture and convey reality, which endows it with unique
ontological significance. The article demonstrates how modern
media alter traditional notions of reality and create new forms of
ontological experience, offering a profound analysis of the
interaction between reality and imagination in
contemporary cinema.
Spirituality and religious coping in patients with cystic fibrosis and their parents
Authors: Çaksen Hüseyin
Published: December 2024

In this article, we reviewed spirituality and religiouscoping in patients with cystic fibrosis (CF) and theirparents to draw attention to the importance ofspiritual and religious dimensions of CF patients.Coping styles seem to have a large effect upon thequality of life of CF patients. In CF, all phasesincluding past, present and future were permeatedwith the search for the meaning of the disease andsocial support, the importance of religion andspirituality, and child's socialization. Children withCF reported a variety of religious/spiritual copingstrategies they nearly always associated withadaptive health outcomes. Persons with late-life CFdiagnoses used spirituality to make meaning,understanding themselves in a collaborativepartnership with their pulmonologist and Allah.Most parents of children with CF reported prayer as helpful and multi-faceted, including individual andgroup prayer. Parents imagined Allah as active,benevolent, and interventionist; found hope in theirbeliefs; felt supported by Allah; and related religionto their motivation to adhere to their child's treatmentplan. Conclusion – We would like to emphasize thatspirituality and religious coping have a large effectupon the quality of life of CF patients and theirparents. Given religion's importance to many peoplein the world, we believe that using religious copingis the right of patients with CF and their parents.Spiritual care for patients with CF and their parentsneeds to be integrated into the curriculum of nursesand health care professionals in collaboration withpastoral caregivers.
Two cases of left putaminal hemorrhage occurring immediately after singing Enka song at karaoke
Authors: Katayama Masahiro , Inoue K. , Naritomi H.
Published: December 2024

We report two cases of hypertensivecerebral hemorrhage (CH) occurring immediatelyafter singing a song at karaoke. Patient 1 was a 71-year-old female, and Patient 2 was an 80-year-oldmale, both of whom had a long history ofhypertension but were free from antihypertensivemedication prior to the attacks. They developed righthemiparesis and dysarthria immediately aftersinging a song enthusiastically. CT demonstrated aleft putaminal hyperdense lesion, typical ofhypertensive CH, in both patients. Followingconservative treatment in the stroke unit, they weretransferred to our rehabilitation hospital under antihypertensive medication. At the time of theattack, Patient 1 sang one "Enka" song, a kind ofJapanese ballad, which needed a high tone and strongvocalization. Patient 2 also sang one Enka song,requiring a high tone and strenuous vocalization, atthe time of the attack. Although singing is consideredbeneficial for mental and physical health, hence itsuse in rehabilitation, singing songs requiring high-tone, strenuous vocalization may trigger CH inhypertensive patients, possibly due to effects similarto the Valsalva maneuver.
USE OF GENE THERAPY IN THE TREATMENT OF ALZHEIMER’S DISEASE – LITERATURE REVIEW
Authors: Sanches Jaqueline Cervantes , Vitoreli Rafaella Bergamo , Nascimento Israel Abraão , Marques Eduarda Boni , Lopes Eduarda Rossi , Domingues Pedro Henrique Lima , Neto José Antonio Pizzolato , Martins Mariana Cupaiol , Novais Paulo Cezar , Da Costa Isabela Bazzo
Published: December 2024

Neurodegenerative diseases are the most common cause of dementia, affecting around 55 million elderly worldwide, Alzheimer’s Disease (AD) corresponds to 60% of all cases. These elderlies reveal memory loss, impairment of language and thought formulation. AD has no cure, only its symptoms are treated, which does not prevent the disease from progressing. Also, throughout the course of brain degeneration progress, drugs no longer show significant effects. For this reason, the set of changes in the DNA of individuals who suffer from the disease can provide an important biomarker that has been the target of studies involving gene therapy. This technique occurs through the correction of modified genes or site-specific modifications, which can be through DNA or RNA, intending to treat or prevent diseases and uses a viral or non-viral vector which helps deliver genetic material to the cell. In the following we searched for clinical studies that portrayed some advances in the treatment of AD using gene therapy techniques. Due to the ability to alter and induce the expression of specific proteins, gene therapy presents a promising future in the restoration and correction of the pathogenic mechanism.
In vitro and in silico cholinesterase inhibitory activities of aaptamine and derivatives from Aaptos suberitoides
Authors: Suciati Suciati , Putri Hanifa Rahma , Palaniveloo Kishneth , Hung Ong Kuan , Rizman-Idid Mohammed , Widyawaruyanti Aty , Nuengchamnong Nitra , Suphrom Nungruthai , Kristiana Rhesi , Mudianta I Wayan , George Mary , Setiawan Edwin
Published: December 2024

Context: Marine sponges from the genus Aaptos produce compounds, often alkaloids, with a wide range of bioactivities. Aaptos suberitoides exhibits anticancer, antioxidant, antibacterial proteasome inhibitory, and receptor activator of NF-kappaB ligand (RANKL) inhibitory activities. Alkaloids from marine sponges have shown potency as cholinesterase inhibitors, one of the targets in Alzheimer’s disease treatment.
Aims: To isolate, identify, and investigate the potency of alkaloids from the water fraction of marine sponge A. suberitoides as cholinesterase inhibitors.
Methods: Bioassay-guided isolation was employed to obtain active alkaloids. The cholinesterase inhibitory assay was conducted based on Ellman’s method with slight modification. Identification of isolated compounds was carried out based on NMR and MS data. The identified compounds were also subjected to molecular docking analysis as well as an ADMET study.
Results: Bioassay-guided isolation of water fraction yielded aaptamine (1) and a mixture containing five benzo[de][1,6]-naphthyridine derivatives, identified based on NMR and LC-MS/MS spectroscopy. Aaptamine (1) inhibited both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50 values of 0.23 and 1.38 µg/mL, respectively. Likewise, the benzo[de][1,6]-naphthyridine mixture of N-demethylaaptanone (2), aaptanone (3), demethylaaptamine (4), aaptosine (5) and 8,9,9-trimethoxy-9H-benzo[de][1,6]-naphthyridine (6) recorded IC50 values of 0.39 and 1.61 µg/mL, respectively. Computational molecular docking analysis calculated the S-score and RMSD values of aaptamine (1) to be the best compared to galantamine for both AChE (PBD: 4EY6) and BChE (PDB: 4BDS) with values of -6.65 kcal/mol, 0.57 Å and -5.98 kcal/mol, 1.05 Å, respectively.
Conclusions: These findings suggest that benzo[de][1,6]-naphthyridine alkaloids from A. suberitoides can be good candidates as cholinesterase inhibitors.
Working Capital Management, Hedging and Macroeconomics Covariates of Default Risk: A Textile Sector Analysis in Pakistan
Authors: Ali Raza Elahi  , Waqas Khan  , Zahra Zainab
Published: December 2024

Default is an increasingly important issue for the Fall, as market stress builds in a weak economic and financial environment rally. The study seeks to investigate if financial tools such as hedging and working capital management can be used for a precaution against default risk in the textile sector of Pakistan. Furthermore, it provides us an analysis on how macroeconomic variables are managed reduces the risk of default. Several elements can potentially impact the likelihood of a corporation experiencing a default on its debt. Nevertheless, this research has only analyzed Working Capital Management, Hedging, and macroeconomic covariables. Data of 102 textile firms was collected for the time of 2015-2020. The objective of this analysis is to assess the influence of these variables on the likelihood of default. The present study employs a logical approach to inquiry. The deductive approach would be the most suitable to evaluate the hypothesis of causation in the study. Our study provides evidence of a strong and statistically significant negative relationship between working capital management and default risk. The importance of the impact of CPI and R&D Investment is observed at a significant level.  The statistical significance of the relationship between GDP growth and the probability of default is acceptable. The statistical significance of the impact of interest rates on default likelihood is insignificant. This study offers significant theoretical contributions by incorporating well-established financial theories, including Credit Rationing Theory, to develop a complete framework for understanding default risk. This article examines how these ideas shed light on the behavior of lenders, conflicts of interest inside agencies, and the impact of free cash flow on corporate decision-making. Furthermore, this study investigates the often-overlooked aspect of working capital management and the role of hedging in risk management. This study offers practical insights for finance experts, corporate administrators, legislators, and investors.
Quality of Medical Waste Management to Enhance Public Trust in Healthcare Facilities
Authors: Muhajirin Al , Sanjaya Ridwan , Hastuti Theresia Dwi , Setianto Benny Danang
Published: December 2024

Healthcare facilities serve as providers of health services for individuals or groups. Healthcare services involve activities that require materials or equipment, generating medical waste that must be recorded and reported. Public trust in medical waste management forms the foundation for maintaining clean healthcare facilities. A clean organization starts with honest and ethical personnel, as reflected in the routine and periodic quality of their work reports. High-quality medical waste management reports can serve as an evaluation and productivity tool for healthcare personnel handling and managing medical waste. This research is crucial as public health relies on clean healthcare facilities. Moreover, the sustainability of medical waste management depends on proper and continuous reporting. Hence, this study explores the quality of medical waste management in enhancing public trust in healthcare facilities. Using a qualitative, descriptive-analytic approach, this research involves informants such as the head of the sanitation department, the head of nursing wards, cleaning service staff, and medical waste handlers. Data collection tools include surveys, interviews, and documentation. Findings reveal that nursing wards producing medical waste need more work reports on medical waste management. Nursing wards must know the volume of materials or medical waste produced. Reports from the sanitation department are partial and not comprehensive, often failing to comply with standard operational procedures for proper medical waste management.
Az agrártáj változásai és a közvetlen támogatások összefüggései 2009 és 2023 között Békésben
Authors: Rákóczi Attila
Published: December 2024

A Közös Agrárpolitika támogatási rendszere kulcsfontosságú a termelők számára. A közvetlen kifizetések feltételei – főként az utolsó két költségvetési időszakban – egyre szigorodó környezetvédelmi, természetvédelmi, tájvédelmi előírásokat is tartalmaznak. Adatfeldolgozáson alapuló vizsgálataimat Békés vármegyében 2009-től napjainkig, azaz 14 évet érintően végeztem. Az adatokat az ún. egységes kérelmekről igényeltem a Békés Vármegyei Kormányhivataltól, valamint a Magyar Államkincstártól (mint agrártámogatási kifizető ügynökségtől). Megállapítottam, hogy a zöldítési előírások a bevezetés éveiben jelentős hatást gyakoroltak a vármegyei termesztett növények diverzifikációjára, a tájképi elemekre. Ugyanakkor az idő előrehaladtával bizonyos visszarendeződés tapasztalható és hasonló vetésszerkezet kezdett kialakulni, mint ami a szabályozások előtti időszakra volt jellemző. Utóbbi igaz a kérelmekben megjelölt egyedi tájelemekre is. Az adatok elemzése arra is rámutatott, hogy a visszarendeződés nem azért következett be, mert nem tartották be az előírásokat a gazdák. Mindezek mellett a 2023-tól induló legújabb támogatási ciklus első éve pozitív változásokat mutat tájvédelmi szempontból.
Pengaruh Promo Harbolnas Terhadap Pembelian Impulsif di Shopeepay
Authors: Rio Kartika  , Ine Mayuni  , Dessy Damayanthy
Published: December 2024

The phenomenon of online shopping that causes the emergence of impulsive purchases, especially at the Shopee Harbolnas festival. The many conveniences offered and the promotional activities carried out stimulate consumers to make impulse purchases. The purpose of this study was to determine the effect of the influence of the harbolnas promo on impulse purchases at shopeepay. This research uses quantitative methods. The sample in this study amounted to 30 respondents using purposive sampling technique. The data analysis process uses simple linear regression analysis. The results of the research on harbolnas promo have a significant positive effect on impulse purchases at shopeepay. The amount of influence is 38%, the remaining 62% is influenced by other factors outside the variables not used in the study
Analisis Motivasi Kerja Terhadap Kinerja Pegawai Kantor Kecamatan Ilir Barat II Kota Palembang
Authors: Muhammad Ilham  , Wita Farla WK
Published: December 2024

This research aims to analyze the influence of work motivation on the performance of employees at the Ilir Barat II District Office, Palembang City. This research uses a quantitative approach by applying simple regression analysis. The population in this study was 58 civil servant employees at the Ilir Barat II District Office, Palembang City, so the sample in this study was the entire population of civil servant employees at the Ilir Barat II District Office, Palembang City, totaling 58 respondents. The data used in this research is primary data obtained from individuals through questionnaires and measured using a Likert scale. Based on the results of the hypothesis analysis (t test), it was concluded that work motivation had a positive and significant effect on the performance of employees at the Ilir Barat II District Office, Palembang City.
Macroeconomic Problems of Pakistan: Impacts and Way Forward
Authors: Bazai Pairman , Khan Ajmal , Khan Mommen
Published: December 2024

This paper assesses the significant macroeconomic challenges faced by Pakistan amidst its ongoing economic crisis. It identifies major issues that have contributed to the economic meltdown. These issues encompass high inflation/stagflation, low foreign exchange reserves, a substantial fiscal deficit, and mounting public debt. Additionally, Pakistan has experienced sluggish economic growth, marked by low productivity and declining exports. The study further delves into the underlying causes of these problems, attributing them to factors such as poor governance, corruption, and political instability. The study sheds light on the current economic turmoil by employing a descriptive approach with a mix of quantitative and qualitative data analysis. To address these pressing challenges, the paper proposes a comprehensive reform agenda encompassing some vital measures. The article also provides policy recommendations that will help policymakers tackle the economic challenges in theory and practice.
ADOPTION OF INTEGRATED PEST MANAGEMENT PRACTICES IN SERICULTURE – A CASE STUDY IN TAMIL NADU
Authors:   Research Extension Center, Central Silk Board, Inam Karisal Kulam (Post), Srivilliputtur - 626 125,Virudunagar (District), Tamil Nadu, India., N Sakthivel
Published: December 2024

Sericulture is an agro-based enterprise, highlysuited to small and marginal farm holdings with less capital investment. Cocoonproduction involves two distinct activities namely, mulberry leaf production,which is the sole feed for silkworm and silkworm rearing. Both mulberry andsilkworm are infested with a number of pests, which affect the cocoon qualityand productivity resulting in economic loss to the farmers. Chemical controlmeasure of pests is widely adopted by the farmers and its hazardous effects onhuman health and beneficial organisms are the least considered. Therefore,Integrated Pest Management (IPM) techniques mainly involving suitablebiological measures have been evolved and popularized for the control ofmulberry and silkworm pests. However, despite the favourable results, theadoption level has remained low. In this context, a study was conducted inThirunelveli and Virudunagar districts of Tamil Nadu with the informationcollected from 60 randomly selected farmers to understand the gap betweenavailable scientific knowledge in IPM practices and its adoption by sericulturefarmers. The results revealed that there was the highest technological gap(87.60 %) in the adoption of biological control measures against the mulberrypests whereas the gap with cultural/ mechanical practices was 33.30 % andminimum 9.80% in the adoption of chemical measures. In case of management ofuzifly menace on silkworms, there was no technological gap with respect tomechanical method of using nylon net to prevent the entry of uzifly inside the rearinghouse, whereas the technological gap of 77.00 % and 71.50% was observed forbiological and chemical control methods, respectively. Thus, the IPM practiceswith the special emphasis on biocontrol method needs to be popularized amongthe farmers by intensified extension efforts for wider adoption at the farmer’slevel.
EFFECT OF SYSTEM OF RICE CULTIVATION ON INSECT PEST INCIDENCE IN PALAKKAD DISTRICT OF KERALA
Authors:   Regional Agricultural Research Station, Pattambi, Kerala, India, K Karthikeyan
Published: December 2024

Experimentswere conducted during the three cropping periods involving twenty farmers inKongad, a major rice growing area in Palakkad district of Kerala, India during2008-2011 using a rice variety Ponmani under two System of Rice Intensificationmethod of cultivation (SRI) and normal system of rice cultivation. Theincidence of yellow stem borer, Scirpophaga incertulas Walker wassignificantly lower in vegetative phase (Dead heart) and reproductive phase(white ear) by 57.85 % and 53.73 % under SRI system in comparison to normalcultivation method. The incidence of other foliage pests like whorl maggot (Hydrelliaphilippina Ferino) and blue beetle (Leptispa pygmaea Baly) were alsolower in SRI system (31.76 and 3.45 % compared to normal system). The incidenceof leaf folder (Cnaphlocrocis medinalis Guenee) another foliage pest inrice was high in SRI system (38.29 % higher over the conventional land system).The grain yield and straw yield was higher in SRI system with 18.52 and 13.35 %respectively over the conventional system. The Cost benefit ratio between theSRI and normal system was 1:2.89 and 1:2.12.
EFFICACY OF SOME HERBAL EXTRACTS ON MICROBES CAUSING FLACHERIE DISEASE IN MULBERRY SILKWORM, BOMBYX MORI L.
Authors:   Department of Zoology, Ayya Nadar Janaki Ammal College (Autonomous), Sivakasi, Tamil Nadu, India - 626 124., K Karthikairaj
Published: December 2024

Sericulture isan ideal enterprise which fits into the socio-economic fabric of India.Improvements in the quantity of silk cocoons and quality of silk depend on thequality of mulberry leaves given to the silkworm and can be achieved by thesupplementation of mulberry leaves with extra nutrients. However, the mulberrysilkworm, Bombyx mori L. is prone to infection of severalmicrobial pathogens resulting heavy loss in the silk output. Among the majordiseases of the silkworm, bacterial flacherie have been found to be very commonin our region and investigation of the haemolymph collected from the diseasedsilkworm revealed that the cultured colony was that of Staphylococcus sp. accordingto its morphological characters. Assessment of the antibacterial activity ofsome herbal extracts prepared from Acalypha indica, Leucas aspera and Ocimumsanctum for the containment of these microbes was then made in ourlaboratory. It was observed that both aqueous and alcoholic extracts of theseherbs proved to be effective against Staphylococcus sp. infectingmulberry silkworm Bombyx mori L. In this context, the alcoholic extractsproduced maximum zone of inhibition against these microbes in the culture platethan the aqueous extracts and that the extracts of Leucas aspera arevery effective against these microbial pathogens followed by the extracts of Ocimumsanctum and Acalypha indica. It is thus inferred that such effectsof herbal extracts could be exploited to control microbial pathogens at thetime of silkworm rearing and to get improved silk production.
Afternoon Tea
Authors: Skinner Julia
Published: December 2024

Afternoon Tea: A History explores the development of the afternoon tea meal, diving deeper than the popular tale of the Duchess of Bedford’s afternoon gatherings to find the meals that inspired those early afternoon teas. Julia Skinner carefully separates the fact and lore around the meal and sets the story of afternoon tea within its historic contexts. Recognizing that a meal’s birth and life never happen in a vacuum, the book sets aside the already well-documented conversations surrounding tea etiquette, instead exploring the social contexts that made the meal possible and popular, moving it from one small subset of the population to a widespread and beloved phenomenon, one that nearly died out at the end of the 20th century before experiencing a resurgence in the 21st.

Afternoon tea is a meal that came of age during the British Empire’s most aggressive expansion, and as such became a meal that was transported to new continents with colonial forces. The book explores how this movement took place and uncovers the different ways tea and colonialism intersect in both the colonial and postcolonial worlds. It also looks at afternoon tea in America, a country that broke from the Empire before the meal was established as a set ritual, but which still has its own complex relationship with the beverage and a continuing fascination with the meal. The book concludes by looking at afternoon tea today, including a handful of interviews that show the range of perspectives about the meal and its place in society, as well as its resurging popularity in the last decade.
Countering Heedless Jihad
Authors: Sheppard James A.
Published: December 2024

Using concepts that are not already a part of the militant discourse as a way to undermine extremism, Countering Heedless Jihad explores a stratagem aimed at defusing jihadist ideology. It explains how to counteract idealist theology using concepts from it, borrowing ideas from some revered Islamic theologians and positioning them in a way that sabotages jihadist ideology. By integrating the theology with viable methods for dissemination, it presents a viable means for confusing existing members of radical groups and for neutralizing their recruiting effort. The book includes contributions by Major General Michael Lehnert, USMC; U.S. Ambassador David J. Dunford; and Dr. Khuram Iqbal.
Academic Library Metamorphosis and Regeneration
Authors: Simons Marcy
Published: December 2024

Academic Library Metamorphosis and Regeneration continues the discussions around change and transformation that are taking place in the library profession today. Academic libraries are undergoing change at a remarkable rate and have been through transitions that were unthinkable before disruptive technology changed everything. For academic libraries, changes in higher education, scholarly communication, and user expectations are driving a continuous need to adjust, transform, and re-create ourselves. This book explores the changes that led us to where we are today, reviews academic libraries that have transformed, and offers suggestions for those who are beginning a change process.
The Kremlin Playbook
Authors: Conley Heather A. , Mina James , Stefanov Ruslan , Vladimirov Martin
Published: December 2024

Russia has cultivated an opaque web of economic and political patronage across the Central and Eastern European region that the Kremlin uses to influence and direct decisionmaking. This report from the CSIS Europe Program, in partnership with the Bulgarian Center for the Study of Democracy, is the result of a 16-month study on the nature of Russian influence in five case countries: Hungary, Slovakia, Bulgaria, Latvia, and Serbia.
Through Students' Eyes
Authors: Zenkov Kristien , Harmon James
Published: December 2024

Today’s educators—pre- and in-service teachers and teacher educators serve increasing percentages of adolescents who have limited relationships to school. These young people are often our most diverse youth; they are frequently English Language Learners (ELLs) and immigrants, and they are too often part of multi-generational dropout and disengagement trends. Teachers are desperate for pedagogical philosophies, curricula, and practices that will support them with helping young people appreciate the value of school, engage or re-engage youth with this most foundational of our public institutions and aid adolescents in the development of the core literacy and writing skills they need to be successful in school and beyond. This volume will assist teachers in recognizing the increasing diversity of their students who often look very different from and have life and school experiences that are very different than those of the educators who serve them. Current and future educators must utilize relevant curricula and creative pedagogies that honor students’ diverse cultures and school and community experiences, while respecting our highest ideals for educational equity and social justice. With this volume, the authors respond to the quickly shifting demographics of schools’ student populations and the disengagement trends teachers frequently encounter but rarely know how to address. We offer compelling, relationship-driven pedagogical principles and instructional strategies that appeal to diverse youths’ voices and cultures and rely on broad, visually- and technology-based notions of literacy.