bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimasi Parameter Model Gravity dengan Metode Penaksiran Kuadrat Terkecil dan Fungsi Hambatan Eksponensial-Negatif (Studi Kasus Kabupaten Sukoharjo)
Authors: Rum Josephin Onesifera
Published: January 2022

Kabupaten Sukoharjo memiliki lokasi yang strategis, yakni letaknya di persimpangan Semarang, Yogyakarta, dan Surakarta. Hal ini akan mendukung pembangunan di Kabupaten Sukoharjo, dan meningkatkan pergerakan. Pergerakan yang meningkat menimbulkan masalah transportasi, oleh karena itu diperlukan perencanaan dengan mengestimasi matriks asal tujuan. Hasil akhir penelitian ini diharapkan dapat diketahui besarnya parameter β pada fungsi hambatan Eksponensial-Negatif dengan metode Kuadrat Terkecil, untuk mengetahui total estimasi distribusi pergerakan di Kabupaten Sukoharjo pada tahun 2021, serta menguji tingkat kemiripan arus lalu lintas hasil pemodelan dan hasil traffic count. Perhitungan estimasi distribusi pergerakan tahun mendatang menggunakan Model Gravity. Nilai parameter β dalam persamaan model Gravity didapatkan melalui kalibrasi Newton-Raphson pada software Matlab. Untuk mengukur tingkat kemiripan dari perhitungan arus lalu lintas hasil pemodelan dan hasil traffic count digunakan Koefisien Determinasi. Hasil dari penelitian ini didapatkan  nilai parameter β sebesar 0,0613, dengan total pergerakan Kabupaten Sukoharjo pada tahun 2021 adalah 16364 smp/jam. Tingkat validitas dari penelitian ini dianggap sangat tinggi karena didapatkan nilai R2 senilai 0,8194.

Kata Kunci : EMME/3, Matriks Asal Tujuan, Matlab, Model Gravity
Estimasi Parameter Model Gravity dengan Metode Penaksiran Kuadrat Terkecil dan Fungsi Hambatan Pangkat (Studi Kasus Kabupaten Sukoharjo)
Authors: Indrawati Haning Tri
Published: January 2022

Perkembangan suatu daerah akan berdampak pada peningkatan jumlah pergerakan, sehingga perencanaan transportasi yang baik diperlukan untuk mengatasi permasalahan transportasi yang mungkin terjadi. Matriks Asal Tujuan (MAT) ialah matriks berdimensi dua dimana dapat mencerminkan pola pergerakan dalam suatu wilayah. Kabupaten Sukoharjo merupakan wilayah kajian pada penelitian ini dan wilayah tersebut dibagi menjadi 36 zona yang terdiri dari 12 zona’’internal dan 24 zona’’eksternal. Tujuan penelitian ini, ialah untuk memperoleh nilai β dari proses kalibrasi Newton-Raphson dengan metode kuadrat terkecil dan fungsi hambatan pangkat, mengetahui besar total distribusi pergerakan MAT menggunakan program EMME/3, selain itu juga untuk mengetahui nilai uji validitas menggunakan koefisien determinasi (R2) berdasarkan perbandingan arus’’lalu’’lintas hasil pengamatan dengan arus lalu’’lintas hasil pemodelan. Nilai arus lalu lintas hasil pemodelan diperoleh dengan membebankan matriks baru ke jaringan jalan dengan metode pembebanan User Equilibrium. Proses pengestimasian MAT menggunakan model Gravity dengan batasan bangkitan dan tarikan yang diolah melalui program EMME/3. Nilai parameter β yang diperoleh sebesar 0,0795. Total jumlah estimasi pergerakan Kabupaten Sukoharjo 2021 sebesar 16.374 smp/jam dengan tingkat validitas (R2) menunjukkan nilai sebesar 0,8272.
Permodelan Sistem Fixed time controller Dan Semi Actuated Controller Pada Simpang Exit Toll Gondangrejo Menggunakan Program Simulasi PTV VISSIM
Authors: Hasiholan Jusuf Fernando
Published: January 2022

Aksesibilitas dari jalan tol dan jalan non tol harus dijadikan perhatian oleh pemerintah khususnya oleh Dinas Perhubungan sebab penyediaan akses tersebut akan menciptakan suatu persimpangan jalan baru dari hasil pertemuan antara jalan umum dan ruas jalan tol yang selanjutnya disebut sebagai simpang exit toll. Lokasi yang dipilih sebagai tinjauan pada penelitan ini adalah Simpang Exit Toll Gondangrejo yaitu simpang tiga bersinyal yang menggunakan sistem Fixed Time Controller dalam pengoperasian lampu lalu lintasnya. Karakteristik pada persimpangan ini memiliki perbedaan dengan persimpangan di perkotaan dimana terdapat perbedaan jumlah arus lalu lintas pada jalan tol dan jalan non tol. Penelitian ini bertujuan untuk memodelkan dan menganalisis kinerja Simpang Exit Toll Gondangrejo menggunakan sistem Fixed Time Controller dan Semi Actuated Controller menggunakan program simulasi PTV VISSIM
Kajian Kuat Tarik Langsung dan Kuat Tarik Belah Beton Memadat Mandiri dengan Kadar Fly Ash 50%, 60%, dan 70% sebagai Pengganti Binder Terhadap Beton Normal
Authors: Istanto Ardha Teo
Published: January 2022

Dunia konstruksi terus berkembang semakin pesat, berbagai inovasi dilakukan dengan prinsip berkelanjutan dan ramah lingkungan. Salah satu inovasi beton ramah lingkungan yang dilakukan adalah menggunakan material fly ash sebagai pengganti semen pada beton SCC yang dapat mengalir sendiri melewati celah besi tulangan yang rapat dan memenuhi ruangan tanpa memerlukan bantuan. Penelitian ini mengkaji bagaimana perbandingan besarnya nilai kuat tarik langsung, kuat tarik belah, dan kuat tekan pada beton HVFAC-SCC dibandingkan dengan beton normal. Pengujian kuat tarik langsung menggunakan benda uji balok 10 x 10 x 25 cm sedangkan pada pengujian kuat tarik belah dan kuat tekan berbentuk silinder dengan diameter 15 cm dan tinggi 30 cm. Hasil penelitian ini menyimpulkan bahwa kuat tarik langsung dan kuat tarik belah sama-sama memiliki nilai lebih kecil dari kuat tekan, nilai perbandingan kuat tarik langsung sebesar 11% dari kuat tekan, dan kuat tarik belah sebesar 8% dari kuat tekan beton.

 

 
Kajian Kuat Tekan, Kuat Tarik Belah, dan Modulus Elastisitas Beton dengan Bahan Pengganti Semen Fly Ash Kadar 15%, 30%, dan 40% Terhadap Beton Normal
Authors: Kuncoro Fajar Bayu
Published: January 2022

Di era modern ini, pembangunan dalam dunia konstruksi di Indonesia terus digencarkan guna mendukung pertumbuhan ekonomi. Seiring dengan digencarkannya pembangunan, permintaan akan kebutuhan beton terus meningkat. Namun, penggunaan beton dalam jumlah banyak dapat memberi dampak terhadap lingkungan yaitu emisi gas karbondioksida yang disebabkan oleh semen. Salah satu alternatif untuk mengganti material semen yaitu menggunakan fly ash guna mengurangi dampak lingkungan sekaligus meningkatkan kualitas dari beton. Penelitian ini bertujuan untuk mengkaji pengaruh kadar fly ash terhadap kuat tekan, kuat tarik belah, dan modulus elastisitas dari beton sebagai bahan pengganti semen.

Penelitian ini menggunakan kadar fly ash 15%, 30%, dan 40% sebagai bahan pengganti dari semen dan dilakukan secara eksperimental. Benda uji yang digunakan berupa silinder diameter 15 cm dan tinggi 30 cm. Untuk mengetahui workabilitas dilakukan pengujian nilai slump terhadap beton segar. Pengujian kuat tekan, kuat tarik belah, dan modulus elastisitas beton dilakukan pada mesin CTM (Compression Testing Machine) dan menggunakan alat ekstensometer untuk mengukur perubahan dimensi beton. Pengujian beton keras dilakukan pada umur 28 hari.

Berdasarkan penelitian didapatkan hasil kuat tekan untuk variasi fly ash kadar 15%, 30%, dan 40% berturut – turut sebesar 38,10 Mpa; 34,05 Mpa; 32,92 Mpa; dan persentase kenaikan masing – masing sebesar 26,65%; 13,17%; dan 9,40%. Pada pengujian kuat tarik belah beton dengan variasi kadar fly ash 15%, 30%, dan 40% mendapatkan hasil berturut – turut sebesar 3,87 Mpa; 2,34 Mpa; 2,08Mpa; dan persentase terhadap kuat tekan masing – masing sebesar 10,16%; 6,89; dan 6,32%. Untuk pengujian modulus elastisitas beton dengan variasi kadar fly ash 15%, 30%, dan 40% mendapatkan hasil berturut – turut sebesar 26281,67 Mpa; 20647,00 Mpa; dan 18312,33 Mpa.
Kajian Kuat Lekat pada Beton High Volume Fly Ash (HVFA) dengan Kadar Fly Ash 50%, 60%, dan 70% dari Berat Binder
Authors: Saputro Vincentius Baskoro Edwin
Published: January 2022

Kemajuan variasi beton pada setiap tahun akan berbeda-beda. Salah satu dari campuran beton yang tidak asing lagi yaitu fly ash. Fly ash sendiri memiliki sifat seperti semen yaitu mengikat campuran beton. Kegunaan fly ash yang lain yaitu dapat meningkatkan kemundahan saat pemcampuran beton. Fly ash berasal dari abu sisa pembakaran batu bara dan sudah tidak dimanfaatkan lagi. Penggunaan fly ash yang sama atau melebihi 50 dari kadar binder tergolong sebagai high volume fly ash concrete. Penelitian pada kali ini akan mengkaji perbandingan kuat lekat pada beton HVFAC kadar fly ash 50%, 60%, dan 70% terhadap beton normal yang akan diuji pada umur 28 hari. Benda uji berupa silinder dengan dimensi diameter 15 cm dan 30 cm untuk tinggi. Setiap masing-masing variasi berjumlah 3 sampel benda uji. Hasil dari perhitungan serta analisis data, diperoleh nilai kuat lekat pada beton HVFAC lebih tinggi dibandingkan dengan beton normal yaitu HVFA 50% sebesar 1,03 MPa, HVFA 60% sebesar 1,05 MPa, HVFA 70% sebesar 1,3 MPa, dan beton normal memiliki nilai paling rendah sebesar 0,235 Mpa.
KAJIAN KUAT TARIK LANGSUNG DAN KUAT TARIK BELAH BETON HIGH VOLUME FLY ASH DENGAN KADAR FLY ASH 50%, 60%, DAN 70%
Authors: Banantya Thoriq Surya
Published: January 2022

Seiring dengan kemajuan inovasi, dunia konstruksi menghadapi perkembangan yang cepat. Perihal tersebut ditunjukkan dengan pembangunan infrastruktur yang sedang digencarkan di Indonesia. Pembangunan infrastruktur tidak terlepas dari pemilihan beton sebagai pilihan utama untuk konstruksi. Kegiatan industri beton adalah salah satu partisipan gas polutan pencemaran udara, seperti gas emisi CO2 dan partikel debu. Salah satu inovasi yang dapat diaplikasikan dalam menanggulangi permasalahan tersebut adalah dengan pendayagunaan abu terbang atau kerap disebut fly Ash selaku subtitusi sebagian semen pada HVFAC (High Volume Fly Ash Concrete). Riset ini bertujuan untuk mengkaji pengaruh kadar fly ash pada uji tarik langsung serta uji tarik belah dari beton sebagai bahan pengganti sebagian semen. Penelitian ini menggunakan kandungan fly ash sebesar 50%, 60%, serta 70% sebagai bahan pengganti dari semen serta dilakukan secara eksperimental. Sampel berwujud balok berdimensi 10 cm x 10 cm x 25 cm untuk benda uji kuat tarik langsung, sedangkan untuk benda uji tarik belah berwujud silinder memakai diameter silinder 15 cm serta tinggi silinder 30 cm. Guna mengetahui workabilitas dilakukan pengujian nilai slump terhadap beton segar. Uji tarik langsung memakai mesin UTM (Universal Testing Machine), sedangkan uji tarik belah dilakukan memakai mesin CTM (Compression Testing Machine). Uji beton keras dilakukan pada usia 28 hari. Berdasarkan penelitian didapatkan hasil kuat tarik langsung untuk HVFAC kadar 50%, 60%, dan 70% serta beton normal berturut – turut 2,92 MPa; 2,28 MPa; 1,93 MPa; 2,20 MPa. Pada pengujian kuat tarik belah HVFAC kadar 50%, 60%, dan 70% mendapatkan hasil berturut – turut 3,68 MPa; 2,69 MPa; 2,29 MPa; 3,02 MPa. Untuk perbandingan uji tarik langsung dengan uji tarik belah untuk HVFAC kadar 50%, 60%, 70%, dan beton normal berturut-turut 79 %; 85 %; 84 %; 73%.
The Impact of Murotal Al-Qur’an on Decreasing Labor Pain In Maternity Mother First Phase
Authors: Argaheni Niken Bayu , Sukamto Ika Sumiyarsi , Nugraheni Angesti , Novika Revi Gama Hatta , Nurhidayati Siti , Sari Atriany Nilam , Kusmawati Iffah Indri , Maulida Luluk Fajria , Wahidah Nurul Jannatul , Maulina Rufidah , Putri Noviyati Rahardjo
Published: January 2022

Background: Murottal Al-Qur'an therapy is a therapy for reading Al-Qur'an which is a religious therapy in which a person is recited verses from the Qur'an for a few minutes or hours so that it has a positive impact on one's body. Murottal Al-Qur'an recitation as a remedy for physical ailments. The aim of the study: To see the effect of murottal Al-Qur'an therapy on reducing the intensity of pain during labor. Method: Systematic review using the database: Google Scholar. The search results that meet the criteria are then analyzed the articles. Results: Pain in labor from many factors: 1) Anxiety and Stress, 2) Supporting Environment and Individuals, 3). Number of Deliveries and 4) Subjective Experience. Conclusion: There is an effect of offering murottal Al-Qur'an therapy on reducing pain intensity, where mothers who give birth after receiving Murottal Al-Qur'an therapy have a lower pain scale than mothers who give birth before getting Murottal Al-Qur'an therapy.

 
Istikhdām Mauqi’ Wib Ikhtibār al-Kitābah al-‘Arabiyah fī Ta’līm Mahārah al-Kitābah Qism Ta'līm al-Lughah al-'Arabiyyah bi Jāmi’ah Muḥammadiyah Malang
Authors: Afifah Nor , Aulannisa Farah , Rosyidi Abdul Wahab , Taufiqurrohman Taufiqurrohman
Published: January 2022

The pandemic condition due to the corona virus has changed the education system which is generally done face-to-face, now it must be done virtually by utilizing online media, one of which is a website. The purpose of this study is to describe 1) How to use the Arabic Typing Test website in learning writing skills at the University of Muhammadiyah Malang. 2) How is the effectiveness of using the Arabic Typing Test website in learning Maharoh Kitabah at the University of Muhammadiyah Malang. The method used in this study is an experimental method with a quantitative approach to measure the effectiveness of the Arabic typing test website. Respondents in this study were second semester students of Arabic language education study program, Islamic religious faculty, University of Muhammadiyah Malang. The data collection used in the form of interviews, observations, questionnaires and tests. The use of the Arabic Typing Test Website in learning writing skills at UMM is effective. The results of this study are that there are 3 stages of using the websie arabic typing test: 1) preparing a computer connected to the internet, 2) instructing students to enter the website with the address http://ajher.co.id, 3) registering using gmail and choose login. And the use of the Website Arabic typing test in learning maharah kitabah at the University of Muhammadiyah Malang is effective. 

 
Chinese Muslims’ Ways of Being Nationalist: Combining Islamic Cosmopolitanism, Acculturation and Social Roles
Authors: Zuhri Achmad Muhibin , Wahyudi Winarto Eka , Hamid Abdulloh
Published: January 2022

One of the ideas that should also be formalized in the reform movement in Indonesia is addressing the issue related to minority groups. Chinese group in Indonesia is one of civil groups that may experience discrimination to date. As a minority ethnic and Muslim community in Indonesia, Chinese Muslims are inevitably in a vulnerable position. They should prove their patriotism toward the nation, Indonesia. This research finds out that the Chinese have been a community that exists way before Indonesia gained its independence: some even play a significant role in Islamization. Chinese Muslims in Indonesia also contribute to establishing the concept of nationalism in Indonesia. Additionally, Chinese Muslims seem to be successful in contextualizing a more substantial concept of nationalism by positioning Chinese ethnic as a cultural entity, not as a representative of “other nation,” and by assimilating local Muslims to play various societal roles. Besides, Chinese Muslims also practice moderate Islamic values to emphasize that their values do not contradict the national values of Indonesia.
Fetal Protection Policies and Corporate Liability of the US Vinyl Chloride Industry, 1974–1991
Authors: Bergen Sadie
Published: January 2022

In the late 20th century, fetal protection policies barred women from hundreds of thousands of industrial jobs on the pretext that if women became pregnant, their fetuses might be harmed by workplace exposure to toxic chemicals. Beginning in the 1970s, these policies set off a decades-long contest between the chemical industry, government agencies, and the judicial system over how to balance the uncertain reproductive health risks against sex discrimination. This article revives the subject of reproductive health and workplace protections through a historical case study of fetal protection policies at Firestone Plastics, a leader in the postwar vinyl chloride industry. I use formerly secret industry documents to argue that Firestone used scientific uncertainty and gender essentialism to skirt new regulatory pressures and minimize corporate liability. Ultimately, fetal protection policies stymied innovative regulatory efforts to protect all workers—not just women—from reproductive hazards in the workplace. (Am J Public Health. 2022;112(2):271–276. https://doi.org/10.2105/AJPH.2021.306539 )
Simulation of Bubonic Plague in BSL-2 Laboratory
Authors: Vagaiskaya A. S. , Trunyakova A. S. , Kombarova T. I. , Dentovskaya S. V.
Published: January 2022

The causative agent of plague, Yersinia pestis, is classified as pathogenicity (hazard) group I agent, which means that the work with “wild type” strains should be carried out in BSL-3 facilities. Y. pestis EV NIIEG is a Δpgm strain, allowing experimental studies to be carried out in BSL-2 laboratories. However, the disease and its progression elicited by such strain do not entirely mirror the infection observed with fully virulent strains. Residual virulence of Y. pestis EV NIIEG strain for mice can be increased under in vivo iron supplementation. The aim of the study was to optimize methodological approaches to modeling experimental plague in laboratory animals following administration of attenuated Δpgm Y. pestis strains with iron dextran. Materials and methods. Simulation of plague infection in outbred mice was carried out through subcutaneous inoculation of Y. pestis EV NIIEG strain with iron dextran supplementation. The animal condition was assessed on a daily basis. In the course of the experiment, the pathological presentation and bacterial content in organs of mice were evaluated. Results and discussion. Mice inoculated subcutaneously with Y. pestis EV NIIEG strain in the presence of iron dextran developed a bubonic plague that resulted in lethal outcome with pathological changes of internal organs, characteristic of plague infection. In case of daily administration of iron, LD50 of Y. pestis EV NNIEG strain for the mice significantly exceeded the same one with a single injection. Differences in the survival rate among animals in the groups with a single and multiple administration of iron compared to the control group were statistically valid. Thus, attenuated Δpgm Y. pestis strains in the presence of iron dextran can be used to model experimental plague in mice with marked pathological changes and lethality in BSL-2 laboratories.
Accommodating Method Effects in Testing Construct Validity Through Confirmatory Factor Analysis
Authors: Widhiarso Wahyu
Published: January 2022

Literatures in the field of psychometrics recommend researchers to employvarious of methods on measuring individual attributes. Ideally,each methods are complementary and measuresthe construct designed to be measured. However, some problems arise when among the methods is unique and unrelated to the construct being measured. The uniqueness of method can lead what is called the method effect. In testing construct validity using confirmatory factor analysis, the emergence of this effect tend to reducing the goodness of fit indices of the model. There are many ways to solve these problem, one of themis controling the method effects and accommodate it to the model. This paper introduces how to accommodate method effecton the confirmatory factor analysis using structural equation modeling. In the application section, author identify the emergence of method effects due to the differences item writing direction (favorable-unfavorable). The analysis showed that method effectemerge from different writing direction.
Intensity of Watching Violent Shows on Television and Tendency to Aggressiveness in Adolescents (Study of Class IX Students of MTS Negeri 1 Bangil)
Authors: Fikri Iqbal
Published: January 2022

Many violence cases as brawls and fights whose committed by juveniles were caused by many factors. This study aimed to find out the relationship between the intensity of watching violence on television with aggressiveness tendencies in adolescents. This study used a quantitative correlation approach that using the intensity watching violence on television as an independent variable (X) and the tendency of aggressiveness as the dependent variable (Y). The sampling technique used random sampling to 69 students of class IX in MTs Negeri 1 Bangil. Measurement of variables used both of two psychologycal scales that constructed by researchers, namely the intensity of watching violence on television scale and aggressiveness tendency scale. Correlation technique of product moment from Pearson was used to analyze data which of calculation helped by SPSS 16.0 for Windows. The result showed that (r) = 0.404; ρ = 0.001 < ρ = 0.01. It means, there is a significant relationship and positive, the higher of the intensity of watching violence on television, the higher of the aggressiveness tendencies in adolescents and vice versa.
Psychological Well-Being of Juvenile Convicts at Class IIA Correctional Institution Sidoarjo
Authors: Susanti Vivi Widya , Maryam Effy Wardati
Published: January 2022

The entry of youth into the prisons would lead them to the loss of independence, difficulties in adapting, and lonely feeling, which ultimately affects the condition of psychological well-being. Here, psychological well-being is an essential condition to make teenagers, i.e., convicts, be able to defend their lives for serving a sentence. The study aims to provide an overview of the psychological well-being of juvenile prisoners and to investigate the factors that influence the formation of psychological well-being. In this case, the study employs an exploratory qualitative approach to the subject of two teenage inmates. The prison chosen is located in Class II A Sidoarjo. The data are obtained from interviewing technique and field notes. The results show that inmates have better psychological well-being than when they entered the prison early. The condition is proved at the subjects’ ability to adjust themselves to the environment, develop self-potential, accept themselves in a positive attitude, self-control and self-reliant, have a purpose to live and be able to establish positive relationships with others. Meanwhile, the factors that influence the formation of psychological well-being in inmates are social support, social interaction, and social skills while they are in a prison.
Self-Concept and Prosocial Behavior Tendency for Accidents on Highways in UMSIDA Students
Authors: Kurniawan Danang , Habibah Nur
Published: January 2022

This study aimed to determine the relationship of self-concept and prosocial behavior tendency for accidents on the highway of the Sidoarjo Muhammadiyah University (Umsida) Students. The samples used sampling techniques incidental to the students at the Umsida who were still being active in the 2012-2013 with 254 students as research subjects. Based on the results of the analysis techniques of Pearson Product Moment correlation obtained rxy value of 0.743 with a significance value = 0.000, p <0.05. This means that the more positive self-concept, the higher the tendency of prosocial behavior on the highway accidents on the Umsida Students. Conversely the more negative self-concept, the lower the tendency of prosocial behavior on highway accidents on the Umsida Students.
Go-Jek Motor Driver's Patience and Work Commitment
Authors: Qodariah Siti , Fikriana Tanti Amalia , Putera Andy , Yasmin Savitri
Published: January 2022

The online-based transportation is very helpful for people in doing activities. Besides being easy to reach, online transportation also offers cheap and fast prices. One company that develops online transportation is Go-Jek. The presence of Go-jek is a negative thing for conventional transportation services., Conventional transportation drivers conduct large-scale demonstrations until anarchic action against Go-Jek drivers. Although there are problems on the road, Go-Jek drivers committed to the company in  carrying out their duties. With these problems, Go-Jek drivers are required to be patient, they persevere to keep working. This is interesting to study. Therefore this research is important to do, because it aims to see how patience and work commitment of Go-Jek drivers. The sample of research subjects was 95 people. The results of this study indicate that most Go-Jek motorcycle drivers have a low level of patience and work commitment
Upper respiratory infection and seasonal variations in the occurrence of in South Korea
Authors: Jung Yong Wook , Kim Eui-hyeok , Lee Sang Ah , Min Seunggi
Published: January 2022

The aim of this study was to examine the effect of seasonal changes on the incidence of preeclampsia in Asian regions and populations, and to evaluate the relationship between upper respiratory infection during pregnancy and the development of preeclampsia. This was a cohort study of women who delivered singletons between 2012 and 2018 in South Korea. A total of 548080 first singleton births were included for analysis. A total of 9,311 patients (1.70%) were diagnosed with preeclampsia. Multivariate analysis showed that older age (≥30 years old), low income, residing in the southern area of Korea, history of smoking, history of heavy drinking, higher body mass index, hypertension, or diabetes mellitus were risk factors for PE. Univariate analysis showed that upper respiratory infection was associated with the incidence of preeclampsia (P=0.0294). However, this association was not maintained in the multivariate analysis (aOR, 1.01; 95% CI, 0.95 - 1.07). After adjusting for confounding variables, the occurrence of PE was the highest in December (aOR, 1.21; 95%CI, 1.10-1.34) and lowest in July and August. This study demonstrated that there are seasonal variations in the occurrence of preeclampsia in Korea. Moreover, upper respiratory infection may be associated with the development of PE.
Pollution Characteristics And Health Risk Assessment of Phthalate Esters In Household Dust In Chengdu, China
Authors: Li Han-Han , Chen Liu-Jun , Yang Zhan-Biao , Xu Xiao-Xun , Xian Jun-Ren , Zhao Liu-Lan , Yang Song , cheng zhang
Published: January 2022

The characteristics and health risks of 15 phthalate esters in household dust and the association with household attributes were investigated in Chengdu, China. The concentrations of total phthalate esters ranged from 87.9 to 3623 μg/g. Di (2-ethylhexyl) phthalate (DEHP) was the dominant compound of phthalate esters with a median of 151 μg/g. The statistical analysis result showed household products and synthetic polymer emission were the main sources of phthalate esters. Smoking, cooking, keeping pets and the use of wooden floor and plastic wallpaper might increase the concentrations of phthalate esters in household dust, but opening windows frequently, and increasing the sweeping frequency might cause the decrease of phthalate esters in the indoor environment. The hazard indexes (HI) values of phthalate esters were all below 1, showed no non-carcinogenic for inhabitants. However, the carcinogenic risk of DEHP was 2.54 ×10-6, implying the carcinogenic risks via exposure to DEHP from Chengdu household dust were noticeable.
Deep investigation of the effects of open trade policies on economic growth in West Africa: The case of the ECOWAS region
Authors: Mamba Essotanam , Kodjo Evlo
Published: January 2022

This study investigates the effects of open trade policies-OTP on economic growth for the Economic Community of West African States during 1980-2017 by applying the method of fixed effect with instrumental variables. Unlike several studies, we move from the univariate to the multivariate regression to show how the coefficient of OTP reacts. The univariate regression supports the positive effect of OTP on growth. However, the multivariate regression indicates that OTP reduces significantly growth. Meanwhile, these findings are robust to various econometric techniques. Furthermore, the paper shows the complementarity relationship between OTP and financial development. The results have important policy implications.
Sinapic Acid Attenuated Cardiac Remodeling After Myocardial Infarction by Promoting Macrophage M2 Polarization Through PPARγ Pathway
Authors: Yang Mei , Xiong Jun , Zou Qiang , Wang Xi , Hu Ke , Zhao Qingyan
Published: January 2022

Background Macrophage polarization is one of the important regulatory mechanisms of ventricular remodeling. Studies have shown sinapic acid (SA) exerts an anti-inflammatory role. However, the effect of SA on macrophage is still unclear. The purpose of the study was to investigate the role of SA in macrophage polarization and ventricular remodeling after myocardial infarction (MI). Methods and results MI model was established by ligating left coronary artery. The rats with MI were treated with SA for 1 week or 4 weeks after MI. The effect of SA on bone marrow-derived macrophages (BMDMs) was also observed in vitro. Cardiac systolic dysfunction was significantly improved after SA treatment. SA reduced MCP-1 and CCR2 expressions and macrophage infiltration. SA decreased inflammatory factors TNF-α, IL-1α and IL-1β levels and increased M2 macrophage marker CD206, Arg-1 and IL-10 levels at 1 week after MI. Myocardial interstitial fibrosis and MMP-2 and MMP-9 levels were declined, and sympathetic nerve marker TH and nerve sprouting marker GAP43 were suppressed after SA treatment at 4 weeks after MI. PPARγ level was notablely upregulated after SA treatment. In vitro, SA also increased expression of PPARγ mRNA in BMDMs and IL-4 induced BMDMs in a concentration-dependent manner. SA enhanced Arg1 and IL-10 expressions in BMDMs and the PPARγ antagonist GW9662 attenuated M2 macrophage markers expressions. Conclusions Our results demonstrated that SA attenuated structural and neural remodeling by promoting macrophage M2 polarization via PPARγ activation after MI.
Comparative study of six failure criteria via numerical simulation of stamped DP600 steel
Authors: Ribas Lucas Marcondes , Gipiela Manolo Lutero , Lajarin Sergio Fernando , Filho Ravilson Antonio Chemin , Marcondes Paulo Victor Prestes
Published: January 2022

During the development of an automobile part obtained by stamping process, time and money are required aiming process planning and set up of a new tooling. One of the difficulties in stamping is to know if the chosen material will have sufficient formability to reach the final form required by the project. Because of this difficulty it is very interesting to propose a method that can accurately simulate the forming process. The failure criteria can be mathematical or empirical models capable of determining the onset of necking for each stress/strain states. It is interesting to find a failure criterion that can be easily determined and provides a good ability to detect the failure accurately. In this study six different failure criteria were studied. Five of them are classified as ductile damage models and they depend on the stress triaxiality and plastic strain. The last criteria depend only on the deformations in the main directions and it is called the forming limit curve (FLC). It was used computational models through finite element analysis (FEA). The formability was evaluated by monitoring the displacement of the punch until the failure of the material. Some failure criteria have been able to provide approximation errors in the range of 0.7 - 5% which makes them interesting for practical implementation in the industry.
Stress Map of India: Efforts during last 30 years
Authors: Subrahmanyam DS
Published: January 2022

National Institute of Rock Mechanics, Bangalore, India is actively involved in conducting in-situ stress measurements for numerous projects both in India and its neighboring countries for the last 30 years. The stress measurements were conducted at various hydroelectric project sites of Himalayan areas at a depth of 350 m from the surface and recently in-situ stress measurements were carried out at a depth of 600 m from the surface at one of the proposed mining blocks of Singareni Collieries Company Limited which is first time in India. With the available data on in-situ stress measurements, the Stress Map of India has been prepared. This is a significant contribution towards design and development of World Stress Map. These stress orientation directions are advantageously useful not only for academic study and research but also for gathering the enormous information on a global perspective to comprehend the geodynamics and plate movement.
Environmental impact of digital health
Authors: Serra César Morcillo , Tanarro Ana Aroca , Cummings Catherine , Fuertes Araceli Jimenez , Martínez José Francisco Tomás
Published: January 2022

Digital health incorporates many efficient new solutions like tele medicine and access to digital test results and medical reports. In this retrospective study, we analyze the environmental impact of digital health activity. We evaluate the net CO2 emissions avoided through a reduction in patient travel to surgeries and medical clinics thanks to the alternative of digital appointments or the digital access to test results and medical reports which avoid the need travel into a clinic for a face-to-face visit or to pick up printed results or reports. During 2020 a total of 640,122 digital appointments were carried out by the healthcare company, which avoided 1,957 net Tons of CO2 emissions, while patients downloaded 3,064,646 digital medical reports through the company portal, which avoided a further 4,698 net Tons of CO2 emissions. These two digital health solutions avoided a net total of 6,655 Tons of CO2 emissions. The present study demonstrates that digital health, specifically digital appointments and digital reports, reduce the environmental impact of healthcare by reducing the need for patient travel, contributing both to population and planet health.
Gradient-flipping-assisted Flux-preserving Wave Reconstruction for Improved Lowspatial- Frequency Recovery and High-contrast Imaging Using in-line Holography
Authors: Keskinbora Cigdem Ozsoy , Broek Wouter Van den , Boothroyd Chris , Dunin-Borkowski Rafal , Aken Peter van , Koch Christoph
Published: January 2022

In-line holography in the transmission electron microscope is a versatile technique, which provides real-space phase information that can be used for the correction of imaging aberrations, as well as for measuring electric and magnetic fields and strain distributions. It is able to recover high-spatial-frequency contributions to the phase effectively but suffers from the weak transfer of low-spatial-frequency information, as well as from incoherent scattering. Here, we combine gradient flipping and phase prediction in an iterative flux-preserving focal series reconstruction algorithm with incoherent background subtraction that gives extensive access to the missing low spatial frequencies. A procedure for optimizing the reconstruction parameters is presented, and results from MgO cubes, and Fe-filled C nanospheres are compared with phase images obtained using off-axis holography.
Deviation of the Orientation Angle of Direction Deep Brain Stimulation Leads Quantified by Intraoperative Stereotactic X-ray Imaging
Authors: Schmidt Josephiene , Buentjen Lars , Kaufmann Joern , Gruber Doreen , Treuer Harald , Haghikia Aiden , Voges Juergen
Published: January 2022

Objective: Directional deep brain stimulation (dDBS) provides multiple programming options. Knowledge of the spatial lead orientation is useful for time efficient programming. Recent studies demonstrated deviations of up to 90° from the intended orientation angle. We examined the deviation of dDBS-lead orientation for leads from two different manufacturers using intraoperative stereotactic (STX) x-ray images.Methods: Intraoperative 2D-x-ray images were acquired after implantation of the first lead (TP1) and the second lead (TP2) enabling the estimation of the spatial position of the first lead at TP1 and TP2 and of changes of the orientation for a defined time period. Two investigators retrospectively estimated the orientation of the directional marker for 64 patients.Results: The mean deviation from intended spatial orientation was 40,8° ± 46.1° for all examined leads. The spatial orientation of the first lead did not significantly change within a period of approximately one hour. The degree of deviation did not differ significantly between two lead manufacturers but depended on the lead fixation technique.Conclusion: Our results showed deviations from the intended orientation angle immediately after the insertion of dDBS leads. The initial spatial orientation remained stable for approximately one hour and was not caused by technical properties of the implanted lead. Hence it was most probably the result of unintended mechanical torsion during insertion and/or fixation. Because precise determination of the lead orientation is mandatory for target-oriented dDBS programming the use of additional imaging suitable for precise 3D-visualization of lead contacts and/or the positioning marker is recommended.
Mitigation of microbial corrosion by Cu addition in X65 pipeline steel in presence of Pseudomonas aeruginosa
Authors: Li Yuchen , Shi Xianbo , Li Jiguang , Zeng Yunpeng , Shen Minggang , Yan Wei , Yang Ke
Published: January 2022

In this study, we focused on the corrosion behavior of X65 pipeline steel and X65Cu pipeline steel in sterile and P. aeruginosa-containing media. The resistance of Cu-bearing X65 pipeline steel against (microbiologically influenced corrosion) MIC caused by P. aeruginosa was investigated. Results demonstrate that the corrosion rate of X65Cu pipeline steel was lower than that of X65 pipeline steel whether it was in a sterile or bacteria-containing media. It is noticeable that, in the presence of P. aeruginosa, X65Cu pipeline steel can prevent the formation of biofilm to a certain degree and reduce the corrosion rate of X65Cu pipeline steel to less than half as that of X65 pipeline steel. In addition, and the maximum pitting depth and average pitting depth of X65Cu pipeline steel were also much lower than that of X65 pipeline steel. The addition of Cu effectively reduced the corrosion of P. aeruginosa to X65 grade pipeline steel and improved the resistance to MIC pitting corrosion.
Prediction of Cardiovascular Risk Comparing Algorithmic Models and Cardiac Risk Factors in Plwha on Art With Overwiegth/ Obesity
Authors: Pérez Alberto Alejandro Miranda , Pedrol Pere Domingo , Robledo Arguiñe Ivonne Urraza , Perez Maria Elena Gutiérrez , Galarza Faviel González , Flores Pablo Ruíz , Goytia Ana Paola Roiz Bollain y , Márquez Francisco Carlos López
Published: January 2022

Objective: The aim of this study was in seropositive subjects from Northern Mexico undergoing cART. Methods: This study included 186 PLWH under cART. The variables analyzed were CD4+ count, viral load, lipid profile, glucose, insulin resistance, anthropometric measures, family history of hypertension and cardiovascular disease, years of treatment and cART scheme. In this study, we used two well-established algorithmic models D:A:D (5-year period) and Framingham (10-year period) for assessing cardiovascular risk. Results: In our study, 51.3% of the PLWH had arterial hypertension; most of the subjects were diagnosed with overweight, hypertriglyceridemia and metabolic syndrome, which are factors that increase the risk of cardiovascular disease. After the assessment with the Framingham model, risk was considered as low, while for the D:A:D model was moderate for this population. Conclusions: PLWH receiving cART present factors that may increase the risk of early heart disease including hypercholesterolemia, hypertriglyceridemia, smoking and age. Although risk was low/moderate after the assessment, it is important to consider other factors such as age of the subjects, overweight/obesity, smoking or coinfections, in addition to years of exposure to cART, which could increase the rate of heart disease.
Can Descending Necrotizing Mediastinitis be treated without surgical intervention? – A case report.
Authors: Lami Feras , Bengheshir Abdulfattah , Abdelhamid Mohamed Hadi Mohamed
Published: January 2022

BackgroundDescending necrotizing mediastinitis (DNM) is a relatively uncommon complication of deep neck infections. We present a case of DNM that has been managed due to early diagnosis and adequate medical treatment, a rare and often lethal complication of odontogenic infections. Case presentationA 17-year-old female patient with a history of swelling in the neck, tongue and lips for two weeks was admitted to the Paediatric Intensive Care Unit of the Cartage Clinic, Tripoli, Libya at the end of December 2019. The predominant underlying oropharyngeal infection was of odontogenic origin, specifically, infection involving the mandibular 3rd molar. The most common option for empiric therapy were broad-spectrum intravenous antibiotics combined with metronidazole or clindamycin. The patient has been discharged from the hospital after four weeks, since being in good health.ConclusionIn view of our experience, we believe that only through aggressive combined medical management by antibiotics directed at both aerobic and anaerobic organisms and drainage at all pus collection sites can reverse the effect of DNM the highly morbid.
Two-Step Heat Fusion Kinetics and Mechanical Performance of Thermoplastic Interfaces
Authors: Xu Zhiping , Wang Shijun , Xu Jun , Shi Jiaxin , Shimizu Takayuki
Published: January 2022

Thermoplastic polymers and composites are ubiquitous in the industry for their reshaping and fusing capabilities at elevated temperature. The quality of heat-fused thermoplastic interfaces is of great concern for adhesion, coating, and welding applications, especially those between dissimilar materials. Kinetic evolution of the microstructures defines the mechanical performance of heat-fusion thermoplastic interfaces, which is studied here using polyethylene and polypropylene as an example. Key factors such as the viscosity and compatibility of polymers and the time and temperature of fusion are discussed by combining molecular-level simulations and structural-level hot-compression experiments. Inter-diffusion and entanglement of polymer chains are identified as the two elementary kinetic steps of the fusion, which dominate the control on the stiffness and strength of the interfaces, respectively. Experimental data shows that the quality of fused interfaces can be improved by reducing the viscosity and the interaction parameter. Following the same set of time-scaling relations as identified in the simulations, the two-step characteristics and their effects on the stiffness and strength are experimentally validated. These findings add insights into the design of fusion processes, laying the ground for the applications of thermoplastic polymers and composites.
Hydrology, Biogeochemistry and Metabolism in a Semi-Arid Mediterranean Coastal Wetland Ecosystem
Authors: Béjaoui Béchir , Salem Hatem , Basti Leila , Feki-Sahnoun Wafa , Dahmani Sana , Canu Donata , Benabdallah Sihem , Blake Reginald , Norouzi Hamidreza , Solidoro Cosimo
Published: January 2022

Experimental and numerical approaches were used to assess the functioning of a flagship coastal wetland ecosystem for improved water management. Very pronounced seasonal contrast in Salinity and Chlorophyll a were found, with high correlation between Chla and Phosphorus during winter and Chla and Nitrogen during summer. Water and Dissolved Inorganic Phosphorus (DIP) and Dissolved Inorganic Nitrogen (DIN) fluxes exhibited seasonal variation, where the lake is a source of DIN and DIP during the wet season. A considerable anthropogenic-driven amount of nitrogen is transferred into N2/N2O to the atmosphere during the dry season with predominance of denitrification-anammox processes. The primary production is impacted by forcing the respiration of the ecosystem to reduce the Net Ecosystem Metabolism so that the system is functioning as heterotrophic. Climate change and anthropogenic pressures explain the deterioration of water quality and possibly the decrease in populations of Palearctic birds, warranting depollution and effective National Wetland Management Strategies through improved water resources management.
Cytotoxicity of curcumin against CD44± prostate cancer cells: Roles of miR-383 and miR-708
Authors: Panahizadeh Reza , Vatankhah Mohammad Amin , Jeddi Farhad , Arabzadeh AmirAhmad , Nejati-Koshki Kazem , Najafzadeh Nowruz
Published: January 2022

Cancer stem cells (CSCs) remaining in the tumor tissues after applying treatments may cause recurrence or metastasis of prostate cancer (PC). Curcumin has the promising potential to target CSCs. Here, we aim to evaluate the cytotoxic effects of curcumin on the expression of miR-383-5p and miR-708-5p and their target genes in CD44+ CSCs and CD44− non-CSCs isolated from the PC3 prostate cancer cell line. We used MTT assay to determine the optimal cytotoxic dose of curcumin on CD44± PC cells. Then, we assessed nuclear morphological changes using DAPi staining. We used Annexin V-FITC/PI to quantify apoptotic cell death. qRT-PCR was also used to detect miRNA and gene expression levels after curcumin treatment. Curcumin significantly enhanced the apoptosis in both CD44− and CD44+ PC cells in a dose-dependent manner (P-value < 0.05). The cytotoxicity of curcumin against CD44− cells (IC50 = 40.30 ± 2.32 µM) was found to be more effective than CD44+ cells (IC50 = 83.31 ± 2.91 µM). Also, curcumin promoted miR-383-5p and miR-708-5p overexpression while downregulating their target genes LDHA, PRDX3, and RAP1B, LSD1, respectively. Our findings indicate that curcumin, by promoting the expression of tumor suppressors, miR-383-5p and miR-708-5p, and inhibiting their target genes, induced its cytotoxicity against CD44± PC cells. We trust that curcumin could be established as a promising adjuvant therapy to current PC treatment options with more research in the clinical field.
Research On The Mapping Grinding of Dimple Surface With Ordered Pattern Based On Topological Theory
Authors: Lyu Yushan , Guoxun Wang , Li Xingshan , Qi Yongchao
Published: January 2022

In order to grind structured dimple surface, a topological mapping grinding method for structured dimple surface was proposed based on grinding kinematics principle and point set topology. Firstly, the topological space of the workpiece and the grinding wheel was established, and the topological features of the structured dimple surface and the structured grinding wheel were extracted based on the analysis of the morphology features of the structured surface with array, staggered and phyllotactic pattern. Then, the topology mapping equation of the grinding process was constructed based on the analysis of the generating mechanism of the dimple surface about grinding geometry, and the structured grinding wheel was designed according to the topology mapping equation. Finally, according to the grinding geometry simulation, the influence of grinding parameters on the generating of dimple surface morphology was studied, and the grinding experiment was carried out. The results show that the structured grinding wheel designed according to the topological features of the structured dimple surface can achieve the grinding of the structured dimple surface. The ground dimple surface is a topological dimple surface, and the feature parameters of the dimple surface can be changed with the change of grinding parameters, but the topological feature properties remain unchanged under the condition of satisfying the proper grinding speed ratio.