bluuebunny/crossref_metadata_2025 huggingface dataset:
The influence of extreme thermal stress on the physiological and psychological characteristics of young women who sporadically use the sauna: practical implications for the safe use of the sauna
Authors: Podstawski Robert , Borysławski Krzysztof , Józefacka Natalia Maja , Snarska Jadwiga , Hinca Bożena , Biernat Elżbieta , Podstawska Anna
Published: January 2024

Background

Many individuals who use the sauna at a temperature of 120°C of higher are not aware of the negative consequences of extreme thermal stress. Despite extensive research into sauna use, the impact of extreme thermal stress on the physiological and psychological characteristics of sauna users have not been examined to date.

Aim

The aim was to determine the effect of 20 min sauna sessions with a temperature of 80°C and 120°C on the physiological and psychological characteristics of women who sporadically visit the sauna.

Methods

The study was conducted on 22 full-time female university students. Physical activity (PA) levels were evaluated with the Polish short version of the International Physical Activity Questionnaire (IPAQ). Anthropometric characteristics were measured before the first sauna session by the InBody270 body composition analyzer. Physiological parameters, including heart, energy expenditure, physical effort, and blood pressure (systolic blood pressure – SBP, and diastolic blood pressure – DBP), were assessed indirectly using Polar V800 heart rate monitors and the Omron M6 Comfort blood pressure monitor. The participants’ wellbeing was assessed with the Profile of Mood States (POMS) questionnaire. The presence of significant correlations between heat exhaustion and heat stress variables and syncope during the second sauna session was examined with the use of classification and regression trees (CRT) and the cross-validation technique.

Results

Twenty-minute sauna sessions with a temperature of 80°C and 120°C induced a significant (p < 0.001) decrease in the values of SBP (excluding the temperature of 120°C), DBP, and body mass, as well as a significant increase in HR and forehead temperature. Exposure to a temperature of 80°C led to a significant (p < 0.001) increase in vigor with a simultaneous decrease in tension, depression, anger, fatigue, and confusion. In turn, sauna bathing at a temperature of 120°C had an opposite effect on the above mood parameters. Vomiting and confusion were the main predictors of syncope that occurred in some of the surveyed women.

Conclusion

Excessive air temperature can induce symptoms characteristic of heat exhaustion and heat stress nausea, heavy sweating, fast weak or strong HR, high body temperature, and confusion. Therefore, sauna bathing at a temperature of 80°C can be recommended to women who sporadically use the sauna, whereas exposure to a temperature of 120°C is not advised in this group of sauna users. The present findings provide highly valuable inputs for managing wellness and SPA centers.
Effect of high-intensity interval training on cardiorespiratory in children and adolescents with overweight or obesity: a meta-analysis of randomized controlled trials
Authors: Deng Yiran , Wang Xianliang
Published: January 2024

Objective

This meta-analysis aimed to examine the effect of high-intensity interval training on cardiorespiratory fitness in children and adolescents with overweight or obesity, and to explore the optimal dose of high-intensity interval training to improve cardiorespiratory fitness in children and adolescents with overweight or obesity.

Methods

Randomized controlled trials on the effects of HIIT on cardiorespiratory fitness in children and adolescents with overweight or obesity were retrieved from six electronic databases, including PubMed, Web of Science, Cochrane Library, CNKI, Wanfang, and VIP. The quality assessment of the included studies was conducted following the revised quality evaluation method based on the PRISMA principles. Keywords for literature search mainly include high-intensity interval, cardiorespiratory fitness, overweight, obese, children, and adolescent, etc.

Results

(1) A total of 18 studies, comprising 581 participants (288 in the intervention group and 293 in the control group), were included and all of them were of moderate to high quality. (2) HIIT had a positive effect on the cardiorespiratory fitness levels of in children and adolescents with overweight or obesity (SMD = 0.91; 95% CI: 0.66, 1.15; p < 0.00001). (3) The improvement in cardiorespiratory fitness was more significant when the HIIT intervention lasted for more than 10 weeks (SMD = 1.04; 95% CI: 0.74, 1.34; p < 0.00001), was conducted 3 times per week, with 2 to 8 sets per session (SMD = 1.13; 95% CI: 0.71, 1.55; p < 0.00001), and maintained a ratio of approximately 1:1 between exercise and rest intervals (SMD = 1.11; 95% CI: 0.73, 1.50; p < 0.00001).

Conclusion and recommendations

(1) Long-term HIIT can improve cardiorespiratory fitness in children and adolescents with overweight or obesity. (2) To achieve significant improvements in cardiorespiratory fitness in a short period, children and adolescents with overweight or obesity can engage in HIIT programs lasting for more than 10 weeks, conducted 3 times per week, with 2 to 8 sets per session, and a ratio of approximately 1:1 between exercise and rest intervals.

Systematic Review Registration

Identifier: INPLASY202350033.
Fuzzy C-Means clustering for physical model calibration and 7-day, 10-year low flow estimation in ungaged basins: comparisons to traditional, statistical estimates
Authors: DelSanto Andrew , Palmer Richard N. , Andreadis Konstantinos
Published: January 2024

In the northeast U.S., resource managers commonly apply 7-day, 10-year (7Q10) low flow estimates for protecting aquatic species in streams. In this paper, the efficacy of process-based hydrologic models is evaluated for estimating 7Q10s compared to the United States Geological Survey's (USGS) widely applied web-application StreamStats, which uses traditional statistical regression equations for estimating extreme flows. To generate the process-based estimates, the USGS's National Hydrologic Modeling (NHM-PRMS) framework (which relies on traditional rainfall-runoff modeling) is applied with 36 years of forcings from the Daymet climate dataset to a representative sample of ninety-four unimpaired gages in the Northeast and Mid-Atlantic U.S. The rainfall-runoff models are calibrated to the measured streamflow at each gage using the recommended NHM-PRMS calibration procedure and evaluated using Kling-Gupta Efficiency (KGE) for daily streamflow estimation. To evaluate the 7Q10 estimates made by the rainfall-runoff models compared to StreamStats, a multitude of error metrics are applied, including median relative bias (cfs/cfs), Root Mean Square Error (RMSE) (cfs), Relative RMSE (RRMSE) (cfs/cfs), and Unit-Area RMSE (UA-RMSE) (cfs/mi2). The calibrated rainfall-runoff models display both improved daily streamflow estimation (median KGE improving from 0.30 to 0.52) and 7Q10 estimation (smaller median relative bias, RMSE, RRMSE, and UA-RMSE, especially for basins larger than 100 mi2). The success of calibration is extended to ungaged locations using the machine learning algorithm Fuzzy C-Means (FCM) clustering, finding that traditional K-Means clustering (FCM clustering with no fuzzification factor) is the preferred method for model regionalization based on (1) Silhouette Analysis, (2) daily streamflow KGE, and (3) 7Q10 error metrics. The optimal rainfall-runoff models created with clustering show improvement for daily streamflow estimation (a median KGE of 0.48, only slightly below that of the calibrated models at 0.52); however, these models display similar error metrics for 7Q10 estimation compared to the uncalibrated models, neither of which provide improved error compared to the statistical estimates. Results suggest that the rainfall-runoff models calibrated to measured streamflow data provide the best 7Q10 estimation in terms of all error metrics except median relative bias, but for all models applicable to ungaged locations, the statistical estimates from StreamStats display the lowest error metrics in every category.
Handbike for Daily Use, Sport, and Rehabilitation Purposes: A Literature Review of Actuation and Technical Characteristics
Authors: Sanguinetta Michele , Incerti Giovanni , Amici Cinzia , Legnani Giovanni
Published: January 2024

With respect to alternative devices like traditional wheelchairs, handbikes can offer advantages from biomechanical and physiological perspectives, to several kinds of users. Assuring high mechanical efficiency and homogeneous force distributions along cycles, and being suitable for indoor and outdoor activities, these systems are used for rehabilitation, sports, and daily applications. From a technical perspective, their main characteristics can vary with the device final purpose and operational context. This review aims to provide an overall outline of handbikes in the literature from a general and comprehensive point of view, up until 2022. The analysis is performed (i) with a systematic approach, without a priori limitations on document type and content focus, and (ii) to identify the areas of interest for the scientific development of these systems. A systematic evaluation method for the identification and analysis of the documents was designed and implemented and the selection criteria, as well as the rationale for the procedure, are described. A specific taxonomy was defined and applied for the subsequent analysis, and each category is specifically evaluated and described, detailing the main outcomes of the literature analysis and relative discussion. Particular attention is paid to actuation strategies and propulsion efficiency. Finally, the main results of the work and future developments for handbikes are briefly synthesized.
Design and Test of Bionic Elastic Row Cleaner with Improved Straw Cleaning Performance
Authors: Wang Qi , Wang Ziming , Zhang Zhanhe , Zhang Kui , Yao Shuo , Zhou Wenqi , Sun Xiaobo , Wang Jinwu
Published: January 2024

No-tillage seeding is of great significance for adjusting and improving soil structure in Northeast China. The conventional no-tillage seeder faces several issues with its row cleaner, such as a low straw cleaning rate and a high working resistance. To address these problems, this paper utilizes the bionic design method and develops a bionic elastic row cleaner inspired by the motion behavior of mole excavation. The bionic structure includes bent teeth and a torsion spring for lateral throwing. The MBD–DEM coupled simulation technology is proposed as the experimental optimization method, and it analyzes the interactions between different row cleaners, straw, and soil. The results indicate that a bionic elastic row cleaner with curved teeth and a torsion spring for lateral throwing (BA-T) had a higher straw cleaning rate and total kinetic energy of straw. It also had lower working resistance. The field test results indicate that the BA-T improved the straw cleaning rate by 13.04% and reduced the working resistance by 39.24% compared to a flat row cleaner. This outcome also validates the accuracy of the simulation experiments. This study contributes to the design of new and efficient row cleaners suitable for maize straw mulching and no-tillage conditions, thereby promoting the adoption of conservation agriculture practices.
Unlocking Sows’ Welfare: The Farm-Level Economic Impact of Phasing out Farrowing Crates for Sows in the European Union’s Pig Breeding Industry
Authors: Malak-Rawlikowska Agata , Majewski Edward , Potori Norbert , Hamulczuk Mariusz , Szili Viktor , Egri Edit
Published: January 2024

The main purpose of this study is to assess the farm-level economic consequences of the planned introduction of a ban on farrowing crates for sows in the EU pig sector, being a response by the European Commission to the ‘End the Cage Age’ Initiative. The impact assessment was carried out in three stages: farm-level analyses based on 225 farm surveys carried out in EU member states and expert consultations, assessments for five alternative scenarios, and the aggregation (scaling-up) of the scenario analysis to the EU-27 sectoral impact. Our findings indicate that the ban on farrowing crates is expected to cause a decrease in the sow population by 21–23%, depending on the scenario, and piglet output in the EU owing to increased sow space requirements, a reduction in production efficiency, and a significant demand for investments. The transition to alternative farrowing systems will lead to increased variable costs related to the farrowing period, namely, veterinary expenses, labour costs, and sow feed costs, as well as expenses associated with higher piglet mortality and increased sow replacement rates. The lower density, resulting from the larger space allowance per sow in free-farrowing systems (approximately 5.5 m2 in free farrowing with temporary confinement and 7 m2 in systems without confinement) will also cause fixed costs per unit (per sow or piglet) to rise in proportion to the decline in the sow herd. Expressed as a percentage of the total production costs per piglet, we can expect a 6–10% increase in the total production costs. The implementation of free-farrowing systems on pig farms will necessitate investments in the modernisation of the existing buildings and new pens for sows. Depending on the scenario, the value of investments ranged from 3.8 to 6.7 billion EUR, at 2021 prices. It should be recognised that beyond the actual improvement in the welfare of sows, there are lingering concerns, including increased production costs, higher piglet mortality rates, and heightened risks to employees. It is essential to consider providing financial assistance to support farms in making a smooth transition to the new systems, as well as an extended transition period to ensure a painless shift.
Myofibrillar Protein Profile of the Breast Muscle in Turkeys as a Response to the Variable Ratio of Limiting Amino Acids in Feed
Authors: Konieczka Paweł , Przybylski Wiesław , Jaworska Danuta , Żelechowska Elżbieta , Sałek Piotr , Szkopek Dominika , Drażbo Aleksandra , Kozłowski Krzysztof , Jankowski Jan
Published: January 2024

The effects of the different dietary levels of Arginine (Arg) in low- and high-methionine (Met) diets on the meat quality and myofibrillar protein profile of breast muscles from turkeys were determined. The experiment had a completely randomized 3 × 2 factorial design with three levels of Arg (90%, 100%, and 110%) relative to the dietary Met levels (30% or 45%). At 42 days of age, eight turkeys from each treatment were sacrificed; the meat pH value was measured at 48 h post-slaughter, and meat color was measured according to the CIE L*a*b* system. The SDS-PAGE method was performed to investigate the myofibrillar protein profile of the breast muscle. The analysis of variance showed a significant effect of the Arg or Met dietary levels on the color parameter b* and the profile of myofibrillar proteins in muscles. The results of the cluster analysis of the myofibrillar protein profile showed that, with a high level of Arg (i.e., 110%), the level of Met 35% or 45% was less important. It can be concluded that the increase in the share of Arg and Met in the diet of turkeys increases the content of some myofibrillar proteins (actinin, desmin, actin) and reduces degradation during the post-slaughter proteolysis of proteins that are considered tenderization indicators.
Utilization of Surplus Air Thermal Energy by a Water Cycle System in a Chinese-Type Solar Greenhouse
Authors: Wang Lu , Li Yiming , Sun Zhouping , Meng Sida , Li Tianlai , Liu Xingan
Published: January 2024

Solar greenhouses are commonly overheated during the day, and the remaining air heat can only be dissipated through ventilation, which is a severe energy waste problem. In order to improve the energy utilization of the greenhouse, this study proposes a water cycle system using surplus air thermal energy, which consists of an air-water heat exchanger, supply and return pipes, a submersible pump, a water tank, and an automatic control system. The proposed system stores the surplus air thermal energy in the greenhouse in the water tank. It releases it into the greenhouse using water circulation, and experimental analyses were carried out using a solar greenhouse in the Shenyang area. The effects of different air and water flow rates on the performance of the surplus air thermal energy water recycling system and the environment inside the greenhouse were analyzed by establishing a CFD model and model validation, and the average difference between the experimental data and the simulated data was 6.98%. The results show that the circulating air flow rate significantly affects the system performance and the environment inside the greenhouse. In the heat collection stage, the water circulation system with an airflow rate of 9 m/s has a minor average temperature difference in the vertical plane of the greenhouse. The water circulation system with an airflow rate of 6.0 m/s collects and releases the most significant heat. The temperature cloud between the vertical and horizontal planes is more uniform. This research provides new ideas for efficient energy use in solar greenhouses.
Vitamin B12 Ameliorates Pesticide-Induced Sociability Impairment in Zebrafish (Danio rerio): A Prospective Controlled Intervention Study
Authors: Robea Madalina , Ilie Ovidiu , Nicoara Mircea , Solcan Gheorghe , Romila Laura , Ureche Dorel , Ciobica Alin
Published: January 2024

Constant exposure to a variety of environmental factors has become increasingly problematic. A variety of illnesses are initiated or aided by the presence of certain perturbing factors. In the case of autism spectrum disorder, the environmental component plays an important part in determining the overall picture. Moreover, the lack of therapies to relieve existing symptoms complicates the fight against this condition. As a result, animal models have been used to make biomedical research easier and more suited for disease investigations. The current study used zebrafish as an animal model to mimic a real-life scenario: acute exposure to an increased dose of pesticides, followed by prospective intervention-based therapy with vitamin B12 (vit. B12). It is known that vit. B12 is involved in brain function nerve tissue, and red blood cell formation. Aside from this, the role of vit. B12 in the redox processes is recognized for its help against free radicals. To investigate the effect of vit. B12, fish were divided into four different groups and exposed to a pesticide mixture (600 μg L−1 fipronil + 600 μg L−1 pyriproxyfen) and 0.24 μg L−1 vit. B12 for 14 days. The impact of the compounds was assessed daily with EthoVision XT 11.5 software for behavioral observations, especially for sociability, quantified by the social interaction test. In addition, at the end of the study, the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), and malondialdehyde (MDA) were measured. The results showed significant improvements in locomotor activity parameters and a positive influence of the vitamin on sociability. Regarding the state of oxidative stress, high activity was found for SOD and GPx in the case of vit. B12, while fish exposed to the mixture of pesticides and vit. B12 had a lower level of MDA. In conclusion, the study provides new data about the effect of vit. B12 in zebrafish, highlighting the potential use of vitamin supplementation to maintain and support the function of the organism.
Proteomic Analysis Reveals the Effects of Different Dietary Protein Levels on Growth and Development of Jersey-Yak
Authors: Yang Guowu , Dai Rongfeng , Ma Xiaoming , Huang Chun , Ma Xiaoyong , Li Xinyi , La Yongfu , Dingkao Renqing , Renqing Ji , Guo Xian , Zhaxi Ta , Liang Chunnian
Published: January 2024

Jersey-yak is a hybrid offspring of Jersey cattle and yak (Bos grunniens). Changing the feeding system of Jersey-yak can significantly improve its growth performance. In this study, tandem mass tag (TMT) proteomics technology was used to determine the differentially expressed proteins (DEPs) of the longissimus lumborum (LL) muscle of Jersey-yak fed different protein levels of diet. The results showed that compared with the traditional grazing feeding, the growth performance of Jersey-yaks was significantly improved by crude protein supplementation after grazing. A total of 3368 proteins were detected in these muscle samples, of which 3365 were quantified. A total of 434 DEPs were identified. Through analyses, it was found that some pathways related to muscle growth and development were significantly enriched, such as Rap1 signaling pathway, mTOR signaling pathway, and TGF-beta signaling pathway. A number of DEPs enriched in these pathways are related to muscle cell development, differentiation, and muscle development, including integrin subunit alpha 7 (ITGA7), myosin heavy chain 8 (MYH8), and collagen type XII alpha 1 chain (COL12A1). In conclusion, the results of this study provide insights into the proteomics of different feeding patterns of Jersey-yak, providing a stronger basis for further understanding the biological mechanism of hybrid varieties.
How to Measure Human-Dog Interaction in Dog Assisted Interventions? A Scoping Review
Authors: De Santis Marta , Filugelli Lorena , Mair Alberto , Normando Simona , Mutinelli Franco , Contalbrigo Laura
Published: January 2024

Human-dog interaction is the working tool through which the therapeutic, educational and recreational goals of dog-assisted interventions (DAIs) are achieved. A better understanding of the characteristics of this interaction could improve the effectiveness of DAIs. This scoping review addresses the question: how has the human-dog connection been measured in the context of DAIs? After searching the Web of Science and Scopus platforms, only peer-reviewed, primary research studies reporting measures of therapy dog-human interaction, relationship and bond were included. A total of 70 included articles provided information on what was measured (interaction, relationship or bond) and how, as well as the general context (DAIs or experimental situations with therapy dogs). While the majority of the articles identified use behavioural analysis methods to analyse the interaction between the participant/recipient and the therapy dog during DAIs, it was possible to identify some more structured tools that assess the participant/recipient’s interaction, relationship or bond with the therapy dog, as well as tools that consider the animal’s perspective or focus on the dog-handler dyad, indicating growing areas of research. The tools and methods identified can be used by both practitioners and researchers to further explore aspects of human-dog interaction in the field of DAIs.
Investigating the Ability of the Tooth and Surrounding Support Tissues to Absorb and Dissipate Orthodontic Loads during Periodontal Breakdown—Finite Elements Analysis
Authors: Moga Radu-Andrei , Olteanu Cristian Doru , Delean Ada Gabriela
Published: January 2024

Herein, the finite elements analysis (FEA) numerical study investigated the absorption–dissipation ability of dental tissues under orthodontic forces, during orthodontic movements and the periodontal breakdown process. Additionally, we investigated the correctness of FEA boundary assumptions up to 2.4 N of loads. Eighty-one models of the second lower premolar were subjected to 810 FEA numerical simulations using Tresca failure criterion under 0.6 N, 1.2 N, and 2.4 N and five movements: intrusion, extrusion, rotation, tipping, and translation. The results showed that both coronal dentine and enamel components had comparable high absorption–dissipation abilities, allowing for only a limited fraction of stresses to reach the circulatory sensitive tissues. Isotropy, linear elasticity, and homogeneity are correct when Tresca is employed up to 2.4 N. Forces of 0.6 N, 1.2 N, and 2.4 N displayed similar qualitative results for all movements and bone levels, while quantitative results doubled for 1.2 N and quadrupled for 2.4 N when compared with 0.6 N. FEA simulations showed 0.6–1.2 N to be safe for application in intact periodontium, while for reduced periodontium more than 0.6 N are prone to resorptive and ischemic risks. For reducing these risks, after 4 mm of bone loss, 0.2–0.6 N are recommended. Rotation and translation were the most stressful followed by tipping.
Multilevel Evaluation Model of Electric Power Steering System Based on Improved Combination Weighting and Cloud Theory
Authors: Deng Zebin , Du Annan , Yang Chenxi , Tong Jianxing , Chen Yu
Published: January 2024

In order to rapidly evaluate the working performance of an Electric Power Steering System (EPS) and clarify the key indicators that affect its working condition, targeted maintenance measures can be taken to improve the vehicle’s handling, stability, and safety. This paper took an EPS system as the research object and decomposed it into five working indicators: steering lightness, steering returnability, steering wheel mid-zone performance, steering wheel vibration, and power assist characteristics. On this basis, the subjective exponential extension Analytic Hierarchy Process (AHP) was combined with the objective improved entropy weight method, and then the combination weighting method of game theory was employed to ensure that the results were reliable. At the same time, a cloud model was introduced to understand the actual situation of each indicator by using cloud parameters and multi-level feedback results. According to the principle of maximum membership and the comprehensive evaluation method, the EPS performance evaluation result was obtained. The results showed that the comprehensive cloud parameter of EPS was U (74.31, 6.08, 0.50), which indicated that its working performance was in good condition, with some minor damage that did not affect its normal use; however, attention should be paid to the maintenance and repair of vulnerable components to ensure the handling, stability, and safety of the vehicle.
An Empirical Study of the Code Generation of Safety-Critical Software Using LLMs
Authors: Liu Mingxing , Wang Junfeng , Lin Tao , Ma Quan , Fang Zhiyang , Wu Yanqun
Published: January 2024

In the digital era of increasing software complexity, improving the development efficiency of safety-critical software is a challenging task faced by academia and industry in domains such as nuclear energy, aviation, the automotive industry, and rail transportation. Recently, people have been excited about using pre-trained large language models (LLMs) such as ChatGPT and GPT-4 to generate code. Professionals in the safety-critical software field are intrigued by the code generation capabilities of LLMs. However, there is currently a lack of systematic case studies in this area. Aiming at the need for automated code generation in safety-critical domains such as nuclear energy and the automotive industry, this paper conducts a case study on generating safety-critical software code using GPT-4 as the tool. Practical engineering cases from the industrial domain are employed. We explore different approaches, including code generation based on overall requirements, specific requirements, and augmented prompts. We propose a novel prompt engineering method called Prompt-FDC that integrates basic functional requirements, domain feature generalization, and domain constraints. This method improves code completeness from achieving 30% functions to 100% functions, increases the code comment rate to 26.3%, and yields better results in terms of code compliance, readability, and maintainability. The code generation approach based on LLMs also introduces a new software development process and V-model lifecycle for safety-critical software. Through systematic case studies, we demonstrate that, with appropriate prompt methods, LLMs can auto-generate safety-critical software code that meets practical engineering application requirements. It is foreseeable that LLMs can be applied to various engineering domains to improve software safety and development efficiency.
Exploring the Efficacy of Mixed Reality versus Traditional Methods in Higher Education: A Comparative Study
Authors: Petruse Radu Emanuil , Grecu Valentin , Gakić Maja , Gutierrez Jorge Martin , Mara Daniel
Published: January 2024

“Immersive technology” is a broad and evolving term that encompasses various kinds of technologies and viewpoints, and has applications in various fields, such as education, healthcare, entertainment, the arts, and engineering. This research paper aims to compare the effectiveness of two teaching methods, namely the conventional method (using PowerPoint slides), and the immersive technology method (initiating a mixed reality with a HoloLens 2 device). The experiment involved two groups of students, aged between 19 and 52 years-of-age, who received different types of instruction: the first group viewed a PowerPoint slide with an image of the human muscular system, and the second group viewed a 3D hologram of the human body that displayed the same muscle groups as in the PowerPoint slide. The researchers wanted to examine if mixed reality devices could improve students’ cognitive abilities and explore if the age of the participants had any impact on the effectiveness of the instruction method. The main findings of this study are that the instruction method that used mixed reality technology, the Microsoft HoloLens 2 device, was more suitable for younger participants, and that traditional instruction methods, such as PowerPoint slides, are more appropriate for older students. While this research provides some valuable insights into the factors that influence student performance in anatomy tests, it has some limitations that should be considered.
Pedagogical and Technical Analyses of Massive Open Online Courses on Artificial Intelligence
Authors: Delgado Algarra Emilio José , Bernal Bravo César , Morales Cevallos María Belén , López Meneses Eloy
Published: January 2024

MOOCs (massive open online courses) are popular distance courses for which anyone can sign up online with no limits on the number of participants. Moreover, artificial intelligence is a combination of algorithms for the development of human and rational capabilities by machines. This article presents a quantitative study with a sample of 734 MOOCs on artificial intelligence from three important platforms. Through exploratory and factor analyses, and with the support of a category system, it is concluded that, there are similarities in terms of access to content, ease of navigation, design, toolbars, consistency, visible hypertexts, browsing support and links, help in content searching, and course development with regard to the technical dimension. Regarding the pedagogical dimension, xMOOCs represent the most extensive international trend, and unidirectional resources predominate. In relation to the content dimension, MOOCs that include content on the emerging and current uses of artificial intelligence in learning and training are remarkable, including three main trends in MOOCs on artificial intelligence: machine learning and education, ethics of AI, and human learning and inclusivity.
Detail Explanation of Coordinate Transformation Procedures Used in Geodesy and Geoinformatics on the Example of the Territory of the Republic of Croatia
Authors: Banković Tedi , Dubrović Marin , Banko Antonio , Pavasović Marko
Published: January 2024

With strong technology improvement, especially GNSS, coordinate transformation has become an essential tool in everyday practice. For this reason, it is beneficial to have a good understanding of the mathematical process of coordinate transformation, as well as the method for calculating transformation parameters. The purpose of this article is to provide a detailed explanation of the coordinate transformation procedure and the calculation of transformation parameters for seven transformation models: 3-parameter, 5-parameter standard and abridged, 7-parameter, 8-parameter, 9-parameter, and 12-parameter. For each transformation model, a basic transformation equation, a procedure for calculating transformation parameters, inverse expression for reversible transformation, as well as characteristics of each model are provided. As an addition, for each model, a numerical example of calculating transformation parameters for the territory of the Republic of Croatia is provided. Additionally, for the example of the 7-parameter transformation, importance of reversible transformation, rotation convention, as well as the form of the rotation matrix used during transformation are demonstrated.
MCPSHA: A New Tool for Probabilistic Seismic Hazard Analysis Based on Monte Carlo Simulation
Authors: Shao Xiaoyi , Wang Xiaoqing , Xu Chong , Ma Siyuan
Published: January 2024

The utilization of the Monte Carlo method in conjunction with probabilistic seismic hazard analysis (PSHA) constitutes a compelling avenue for exploration. This approach presents itself as an efficient and adaptable alternative to conventional PSHA, particularly when confronted with intricate factors such as parameter uncertainties and diverse earthquake source models. Leveraging the Monte Carlo method and drawing from the widely adopted Cornell-type seismicity model in engineering seismology and disaster mitigation, as well as a seismicity model capturing temporal, spatial, and magnitude inhomogeneity, we have derived a formula for the probability of earthquake intensity occurrence and the mean rate of intensity occurrence over a specified time period. This effort has culminated in the development of a MATLAB-based program named MCPSHA. To assess the model’s efficacy, we selected Baoji City, Shaanxi Province, China, as our research site. Our investigation delves into the disparity between occurrence probability and extreme probability (a surrogate commonly employed for occurrence probability) in the Baoji region over the next 50 years. The findings reveal that the Western region of Baoji exhibits a heightened hazard level, as depicted in the maps, which illustrate a 10% probability of exceedance within a 50-year timeframe. The probability of earthquake occurrence under various intensities (VI, VII, and VIII) over 50 years follows a declining trend from west to east. Furthermore, the likelihood of seismic intensity exceeding VI, VII, and VIII indicates the lowest exceeding probability in the northeast and the highest in the northwest. Notably, for intensities VI-VII, the difference between occurrence probability and extreme probability approaches twice, gradually diminishing with increasing intensity. This study underscores the MCPSHA model’s efficacy in providing robust technical support for mitigating earthquake risk and enhancing the precision of earthquake insurance premium rate calculations.
Rays in the Shadows: Batoid Diversity, Occurrence, and Conservation Status in Fiji
Authors: Glaus Kerstin , Gordon Luke , Vierus Tom , Marosi Natasha D. , Sykes Helen
Published: January 2024

Over recent decades, elasmobranchs (sharks, rays, and skates) have been increasingly recognized among the world’s most threatened marine wildlife, leading to heightened scientific attention. However, batoids (rays and skates) are relatively understudied, especially in Large Ocean States of the Pacific. This synthesis compiles insights on batoid diversity and occurrence in Fiji’s waters by integrating a literature review, participatory science programs such as the Great Fiji Shark Count (GFSC) Initiative, Projects Abroad Fiji (PA), Manta Project Fiji (MPF), and iNaturalist, along with environmental DNA. Nineteen batoid species from seven families were identified: 19 species from the literature, 12 from participatory science programs, and six from eDNA analysis. Notably, this study provides the first photographic evidence for the bentfin devil ray (Mobula thurstoni, Lloyd, 1908) in Fiji. GFSC data indicated the highest species diversity in the Western Division, with spotted eagle rays (Aetobatus ocellatus, Kuhl, 1823) and maskrays (Neotrygon sp.) being observed most. In-person interviews conducted by PA provided information on the occurrence of wedgefishes and potentially sawfishes. MPF records and iNaturalist uploads were dominated by reef manta rays (M. alfredi, Krefft, 1868), while the pink whipray (Pateobatis fai, Jordan and Seale, 1906) yielded the most DNA sequences. Overall, 68.4% of the species face an elevated extinction risk based on the International Union for the Conservation of Nature Red List criteria. Although caution is warranted with older literature-based records for the giant guitarfish (Glaucostegus typus, Anonymous [Bennett], 1830), giant stingaree (Plesiobatis daviesi, Wallace, 1967), and the lack of sawfish verification, this synthesis highlights the effectiveness of a combined methodological approach in establishing a reference point for the diversity and occurrence of this understudied taxon in Fiji.
Cystic Echinococcosis in Hospitalized Children from Western Romania: A 25-Year Retrospective Study
Authors: Paduraru Ana Alexandra , Lupu Maria Alina , Popoiu Calin Marius , Stanciulescu Maria Corina , Tirnea Livius , Boia Eugen Sorin , Olariu Tudor Rares
Published: January 2024

Cystic echinococcosis (CE) is a cosmopolitan parasitic disease caused by Echinococcus granulosus. We aimed to assess the epidemiological aspects of the disease in hospitalized children from Western Romania, a well-known endemic area for CE. We retrospectively investigated the medical records of children hospitalized between 1998 and 2022. A total of 144 patients were included, and 58.3% were from rural areas. The number of cases increased with age, from 9% in the age group 3–5 years to 59.7% in the age group 11–17 years. The liver was more frequently affected (65.3%), and a significant association between gender and the affected organ was noted; liver cysts were more frequently diagnosed in girls, while lung cysts were recorded mostly in boys. Complications were more frequently reported in patients with pulmonary CE compared to hepatic CE (p = 0.04). Boys had more complications (16/23, 69.6%) compared to girls (7/23, 30.4%) (p = 0.03). A third of the children were hospitalized for more than 14 days, and multiple hospitalizations were recorded in 31.3% of the patients. This paper provides new insights into the epidemiologic features of cystic echinococcosis in children from Western Romania. Our findings indicate that exposure to the parasite starts in childhood, and the rate of hospitalization increases with age. Public health strategies should be implemented and permanently improved in order to lower the prevalence of CE in children.
Nanoencapsulated Curcumin: Enhanced Efficacy in Reversing Memory Loss in An Alzheimer Disease Model
Authors: Savall Anne Suély Pinto , de Mello Jhuly Dorneles , Fidelis Eduarda Monteiro , Comis-Neto Antonio Alvenir , Nepomuceno Maria Regina , Pacheco Camila de Oliveira , Haas Sandra Elisa , Pinton Simone
Published: January 2024

Investigating new drugs or formulations that target Alzheimer disease (AD) is critical for advancing therapeutic interventions. Therefore, this study aimed to assess the effectiveness of nanoencapsulated curcumin (NC Curc) in alleviating memory impairment, oxidative stress, and neuroinflammation in a validated AD model. Male Wistar rats were given bilateral intracerebroventricular injections of either saline or streptozotocin (STZ) (3 mg/3 µL/site) to establish the AD model (day 0). On day 22, daily oral administrations of curcumin (6 mg/kg), NC Curc (6 mg/kg), or a vehicle (unloaded NC) were initiated and continued for 14 days. NC Curc significantly reversed memory deficits in object recognition and inhibitory avoidance tests induced by STZ. Both formulations of curcumin attenuated elevated acetylcholinesterase activity caused by STZ. Importantly, NC Curc alone effectively mitigated STZ-induced oxidative stress. Additionally, NC Curc treatment normalized GFAP levels, suggesting a potential reduction in neuroinflammation in STZ-treated rats. Our findings indicate that NC Curc improves memory in an AD rat model, highlighting its enhanced therapeutic effects compared to unencapsulated curcumin. This research significantly contributes to understanding the therapeutic and neurorestorative potential of NC Curc in AD, particularly in reversing pathophysiological changes.
A Wind Protection Design Strategy for Airport Terminal Door Bucket Space Based on Wind Environment Simulations
Authors: Yang Lu , Lai Wentao , Yan Gaoning , Zhen Meng
Published: January 2024

Airport terminal buildings are large public transportation buildings with complex functions and dense crowds, and the wind environment has significant effects on passenger comfort and the energy consumption of air conditioning systems. In this study, we investigated Xianyang T3 Terminal as an example and used the Phoenics software to conduct comprehensive simulations based on different door bucket forms and parameters, as well as comprehensively considering the impacts of different outdoor wind environments. A terminal door bucket windproof design strategy was proposed based on our results. The results showed that door buckets could effectively reduce the entry of outdoor wind, and built-in door buckets performed the best. The width of the door bucket should be set to 9.3–11.3 m and the depth of the door bucket to 6.7–7.7 m. The height of the door bucket had little impact. A side door should be added to the door bucket, so it can be opened when the outdoor wind speed is high, and a mechanical ventilation system should be introduced to improve the indoor ventilation.
Catalyst Coatings for Ammonia Decomposition in Microchannels at High Temperature and Elevated Pressure for Use in Decentralized and Mobile Hydrogen Generation
Authors: Weissenberger Tobias , Zapf Ralf , Pennemann Helmut , Kolb Gunther
Published: January 2024

We report an investigation of catalyst performance for the decomposition of ammonia under industrially relevant conditions (high temperatures of up to 800 °C and an elevated pressure of 5 bar) with further emphasis on their stability at high reaction temperatures. The catalysts were applied and tested as coatings in 500 µm wide channels of microreactors. Nickel-based catalysts were studied and compared to a ruthenium-based catalyst supported on SiO2. The effect of the support on the catalytic performance was investigated, and CeO2-supported nickel catalysts were found to exhibit the highest activity. Promoters were applied to increase the NH3 decomposition activity of the Ni/CeO2 catalysts. The addition of cesium led to a slight reduction in activity, while lanthanum, calcium, and barium doping resulted in increased activity. In particular, the barium-doped Ni/CeO2 catalyst showed very high ammonia conversion and closed the activity gap with respect to ruthenium catalysts at reactor temperatures of 650 °C and higher. The hydrogen production rates achieved in this work were compared to values in the literature and were shown to exceed values found earlier for both nickel- and ruthenium-based catalysts. Furthermore, the ruthenium-based catalysts under investigation were rapidly deactivated at 700 °C, while the nickel-based catalysts did not show deactivation after 220 h on time on stream at 700 °C.
Hydrothermally Synthesized MoS2 as Electrochemical Catalyst for the Fabrication of Thiabendazole Electrochemical Sensor and Dye Sensitized Solar Cells
Authors: Khan Mohd Quasim , Ahmad Khursheed , Raza Waseem , Khan Rais Ahmad , Sutradhar Manas , Paul Anup
Published: January 2024

In this work we reported the hydrothermal preparation of molybdenum disulfide (MoS2). The phase purity and crystalline nature of the synthesized MoS2 were examined via the powder X-ray diffraction method. The surface morphological structure of the MoS2 was examined using scanning electron microscopy and transmission electron microscopy. The specific surface area of the MoS2 was calculated using the Brunauer-Emmett-Teller method. The elemental composition and distribution of the Mo and S elements were determined using energy-dispersive X-ray spectroscopy. The oxidation states of the Mo and S elements were studied through employing X-ray photoelectron spectroscopy. In further studies, we modified the active surface area (3 mm) of the glassy carbon (GC) electrode using MoS2 as an electrocatalyst. The MoS2 modified GC electrode (MSGC) was used as an electrochemical sensor for the detection of thiabendazole (TBZ). Linear sweep voltammetry (LSV) was used as the electrochemical sensing technique. The MSGC exhibited good performance in the detection of TBZ. A limit of detection of 0.1 µM with a sensitivity of 7.47 µA/µM.cm2 was obtained for the detection of TBZ using the LSV method. The MSGC also showed good selectivity for the detection of TBZ in the presence of various interfering compounds. The obtained results showed that MoS2 has good electrocatalytic properties. This motivated us to explore the catalytic properties of MoS2 in dye sensitized solar cells (DSSCs). Thus, we have fabricated DSSCs using MoS2 as a platinum-free counter electrode material. The MoS2 counter electrode-based DSSCs showed good power conversion efficiency of more than 5%. We believe that the present work is beneficial for the scientific community, and especially for research surrounding the design and fabrication of catalysts for electrochemical sensing and DSSC applications.
Investigation into Cardiac Myhc-α 334–352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity
Authors: Sur Meghna , Rasquinha Mahima T. , Mone Kiruthiga , Massilamany Chandirasegaran , Lasrado Ninaad , Gurumurthy Channabasavaiah , Sobel Raymond A. , Reddy Jay
Published: January 2024

Myocarditis is one of the major causes of heart failure in children and young adults and can lead to dilated cardiomyopathy. Lymphocytic myocarditis could result from autoreactive CD4+ and CD8+ T cells, but defining antigen specificity in disease pathogenesis is challenging. To address this issue, we generated T cell receptor (TCR) transgenic (Tg) C57BL/6J mice specific to cardiac myosin heavy chain (Myhc)-α 334–352 and found that Myhc-α-specific TCRs were expressed in both CD4+ and CD8+ T cells. To investigate if the phenotype is more pronounced in a myocarditis-susceptible genetic background, we backcrossed with A/J mice. At the fourth generation of backcrossing, we observed that Tg T cells from naïve mice responded to Myhc-α 334–352, as evaluated by proliferation assay and carboxyfluorescein succinimidyl ester staining. The T cell responses included significant production of mainly pro-inflammatory cytokines, namely interferon (IFN)-γ, interleukin-17, and granulocyte macrophage-colony stimulating factor. While the naïve Tg mice had isolated myocardial lesions, immunization with Myhc-α 334–352 led to mild myocarditis, suggesting that further backcrossing to increase the percentage of A/J genome close to 99.99% might show a more severe disease phenotype. Further investigations led us to note that CD4+ T cells displayed the phenotype of cytotoxic T cells (CTLs) akin to those of conventional CD8+ CTLs, as determined by the expression of CD107a, IFN-γ, granzyme B natural killer cell receptor (NKG)2A, NKG2D, cytotoxic and regulatory T cell molecules, and eomesodermin. Taken together, the transgenic system described in this report may be a helpful tool to distinguish the roles of cytotoxic cardiac antigen-specific CD4+ T cells vs. those of CD8+ T cells in the pathogenesis of myocarditis.