bluuebunny/crossref_metadata_2025 huggingface dataset:
Creating an Intercultural User-Centric Design for a Digital Sexual Health Education App for Young Women in Resource-Poor Regions of Kenya: Qualitative Self-Extended Double Diamond Model for Requirements Engineering Analysis
Authors: Soehnchen Clarissa , Rietz Annika , Weirauch Vera , Meister Sven , Henningsen Maike
Published: September 2023

Background

The stigmatization around sexual health due to culture, religious traditions, and norms leads to myths and a lack of available information and resources related to universal access to sexual and reproductive health services. Additional sexual health education not being part of the Kenya school curriculum leads to insufficient access to knowledge about safe contraception, menstruation, and female genital mutilation. A digital app could support and provide education and information for universal equal access, addressing United Nations Sustainable Development Goals 3, 4, and 5.

Objective

The study targeted the requirements for establishing a reusable framework to develop a successful accessible web-based sexual health education app and the behavioral intention to use it to obtain sexual health information by mainly young women in Kenya.

Methods

The double diamond model, with a problem room including the discover and define phases, enriched with cultural aspects and modeled to a self-expanded intercultural research model was used in a user-centered design thinking approach to develop a framework for requirements engineering analysis. For problem identification, semistructured pilot phase interviews based on Consolidated Criteria for Reporting Qualitative Research guidelines were conducted, followed by expert interviews for qualitative content analysis. A sample size of 12 pilot phase interviews and 5 expert interviews was determined using data saturation. The responses were coded and analyzed according to the affinity mapping method.

Results

The requirements engineering analysis showed potential enablers of and barriers to the use of a digital sexual health education app. Through this qualitative study, a conservative cultural background, classic text communication, and the influence of social affiliation within society were identified as barriers, which should be enhanced through visual and auditory channels as well as a fictional character in the app.

Conclusions

The developed intercultural research model provides an impetus to providing digital sexual health education, integrating culture-specific aspects in the design process, while focusing on cultural and religious stigmata. The reusable framework enables identifying and overcoming hurdles in providing information about taboo and intimate topics. The overall use of online education tools focusing on intimate topics is correlated with accessibility and understanding specific cultural needs while delivering content on a basic and comprehensive level. It helps the target user from a social conservative background and in resource-poor circumstances to benefit from a digital educational solution.
Professional training and continuing professional development of masters in dentistry under the extreme conditions of COVID-19 and martial law in Ukraine
Authors: Kulbashna Ya.A. , Skrypnyk I.L.
Published: September 2023

The III Scientific and practical conference with international participation “Professional training of dentistry specialists in the extreme conditions of modernity”, which was held on April 26–27, 2023 at the Dental Medical Center of the Bogomolets National Medical University, was devoted to the issues of continuous dental education in Ukraine in the conditions of war. The conference was organized by the Ukrainian Association of Dental Education (UADE), where the chairman of the organizing committee was the president of the UADE, professor Yaroslava Kulbashna and the deputy chairman — vice president of the UADE, associate professor Iryna Skrypnyk. It was very pleasant to feel the support of the rectorate of the Bogomolets National Medical University — its rector Yuriy Kuchin, vice rectors, professors Oleksandr Naumenko, Rimma Skrypnyk and Oleksandr Kanyura, president of the NGO «Ukrainian Dental Association», professor Iryna Mazur, director of the Institute of Postgraduate Education, professor Tatiana Vezhnovets, members of the UADE and the student council of the dental faculty. The representative level of the guests and participants of the event showed that despite the war in our country, the topic of continuing education of future dentists, interns and doctors is in the focus of attention of government officials in the field of education and medicine, teachers, students, postgraduate students of higher medical and postgraduate education institutions. In particular, the event was attended by First Deputy Minister of Health of Ukraine, professor Serhiy Dubrov, People’s Deputy of Ukraine Inna Sovsun, director of the Department of the Ukrainian State Center for International Education of the Ministry of Education and Science of Ukraine, candidate of historical sciences Olena Shapovalova.
Adam Smith: construcción para una exégesis de la economía política
Authors: Solorza Marcia
Published: September 2023

Analizar cómo los fundamentos filosófico morales del iusnaturalismo y el racionalismo seguidos por Adam Smith trazaron la ruta de la defensa del liberalismo político, expresada en la creación de una sociedad civil con un Estado Liberal y económico es el objeto del presente ensayo. La sistematización de los conocimientos, sobre ética, armonía, sentido de propiedad, egoísmo y simpatía, par de sentimientos opuestos, son motivos para crear una trama explicativa, un conjunto de postulados que sirven de soporte a una teoría del proceso económico de la producción industrial- mercantil. Adam Smith se adelantó a su tiempo al enunciar al trabajo como el rol central en la creación del excedente en la: producción, distribución y consumo desde la visión de la economía política. La distribución del ingreso obtenido por la venta del producto se distribuye de acuerdo con la posición de los grupos sociales en la producción y realización económica. La acumulación del capital se amplía como parte del ingreso para continuar ensanchando la generación de valor.
Riqueza de las naciones y remesas en México
Authors: García Rodolfo , Gaspar Selene
Published: September 2023

Ante el aniversario de tres siglos del nacimiento de Adam Smith, se han multiplicado los trabajos y comentarios sobre el impacto y pertinencia de las propuestas centrales de su libro Investigación sobre la naturaleza y causas de la riqueza de las naciones de Adam Smith (1776), obra que plantea la importancia de los mercados, la división del trabajo, la especialización de los países y la intervención estatal en la generación de riqueza y el bienestar de la población. A partir de dichos planteamientos y frente a la realidad económica actual de México sostenemos que las remesas recibidas en el país de los migrantes mexicanos en Estados Unidos tienen un significado contradictorio en la percepción de la riqueza nacional. Las remesas representan un flujo creciente de dinero del exterior que ayuda a estabilizar macroeconómicamente a la economía nacional, apoya el crecimiento económico en las regiones con mayor recepción y aumenta el bienestar en 1.8 millones de hogares receptores. La pandemia del COVID-19 impulso el crecimiento del mercado digital conocido como Fintech en el envío de remesas, aprovechando la difusión de las tecnologías de la información y la reducción de sus costos, las  empresas en el mercado de transferencia de remesas han  aprovechado en su beneficio la coyuntura de expansión en ese mercado. Por otro lado, el monto de la migración y las remesas es proporcional a las diversas crisis económicas durante 40 años y la incapacidad crónica de generar desarrollo económico con empleo y bienestar para toda la población. En conclusión, se corrobora la mayor vulnerabilidad de los perceptores de remesas para enfrentar situaciones catastróficas ante la incertidumbre de su crecimiento en los años siguientes, situación que se agravaría aún más sin las remesas.
Stalker: la imagen poética de la ciencia ficción
Authors: Bellamy Ortiz Adriana
Published: September 2023

El cine de ciencia ficción ha tenido importantes transformaciones vinculadas tanto a los avances tecnológicos de la industria cinematográfica como a la historia del cine en general. En muchos casos, aunque las películas que forman parte de este género suelen tener un énfasis visual en los efectos especiales y lo espectacular, en otras ocasiones más bien forman parte de la estilística-estética de un autor particular. De tal forma, Stalker, realizada en 1979 por Andréi Tarkovski, adapta la novela Picnic a la orilla del camino de los hermanos Boris y Arkadi Strugatsky para integrarla a una obra fílmica caracterizada por un trabajo minucioso de lo que Gilles Deleuze denomina la imagen-tiempo, basada en la duración de la toma larga, la composición visual, la presencia de los objetos al interior del encuadre, un empleo puntilloso de la luz y la amplitud del plano sonoro, tanto musical como analógico. En este artículo, mediante el análisis fílmico y comparativo de algunas secuencias, se verá cómo el proceso de adaptación parte de la novela para crear una de las películas más significativas del universo tarkovskiano no sólo porque fue el último proyecto en su tierra natal, sino también por la postura crítica que se traslada del texto a la pantalla.
Publication Activity Analysis of Scientific Practical Journal “Intelligent Systems in Manufacturing”
Authors: Muravyov V. V. , Muravyova O. V.
Published: September 2023

The analysis of publication activity of the journal as at 2021. Since January 2019 journal “Intelligent Systems in Manufacturing” has been reorganized and today it has 2 sections for engineering sciences: “Instrumentation” and “Informatics”. Since that time, the journal has been publishing 14 articles per issue having 9 pages each on average. The editorial board consists of 22 scholars, among them 4 foreign scholars and 4 scholars from other regions of the Russian Federation. Blind peer view of articles is applied to enhance the quality of an article, peer views are published on the portal E-library, and the number of the rejected articles has increased due to low scientific merit up to 20 per cent. The journal site and the information of the journal in Russian Science Citation Index have been upgraded. Article content has been enhanced by means of complementary parallel headlines and information in English: article headline, authors, abstract, references, picture captures, and tables. Abstract and conclusion informative value are subjected to restricted requirements, requirements to references became as follows: at least 15 references to articles published during last 3 - 5 years including foreign ones. Publication activity of the journal in 2020 compared to 2018 has significantly increased according to majority of indicators: 2-year impact-factor for RSCI has become 1.5 times higher, a 2-year impact-factor for RSCI taking into account to citation of all references has also become 1.5 times higher: a 2-year impact factor for RSCI core has become 3 times higher. A 5-year impact factor for RSCI does not intensively respond to the changes happened during the last years, however, it is increasing. A 5-year-factor for RSCI core has the tendency to 1.5-time increasing. Percentage of a 2-year self-citation factor of the journal is not stable and exceeds 50 per cent. A 2-year self-citation factor among the authors is hardly decreasing and accounts for 70 per cent revealing the major disadvantage.
PARTICIPATION OF SOCIALLY ORIENTED NON-PROFIT ORGANIZATIONS IN THE TRANSFORMATION OF THE SOCIAL SPHERE ON THE EXAMPLE OF THE UDMURT REPUBLIC
Authors: Galiakhmetov R. A. , Salikova L. H.
Published: September 2023

The participation of socially oriented non-profit organizations of the Udmurt Republic in regional, federal and national projects in Russia is considered. The relevance of the topic raised is due to the fact that the non-profit sector in our time plays a significant role in a market economy. Thanks to their activities and assistance, positive trends are observed in improving indicators in the field of demography, education, ecology, healthcare, culture, science, sports and other significant areas, which increases the efficiency of the socio-economic development of the region and ensures higher economic growth rates. Each SO NPO of Udmurtia, solving a certain problem, ensures the construction of a favorable image of the republic, thereby strengthening the positive attitude towards it on the part of investors, the state, and the population. The characteristics and dynamics of the main directions of SO NCOs of Udmurtia are given, examples are given. In conditions of social and economic tension, including the coronavirus pandemic, public organizations are the first to come to the rescue, therefore, state support measures for the non-profit sector of the region are increasing. In addition to the analysis of this work, a proposal is submitted for consideration, an experiment on the consolidation of SO NPOs into separate parties (factions, groups) that can compete with state and municipal structures, thereby increasing the efficiency of the functioning of the system for providing social services.
FEATURES OF THE APPLICATION OF FUNDAMENTAL ANALYSIS FOR A PORTFOLIO OF SHARES OF PUBLIC COMPANIES INVESTING IN CRYPTO ASSETS
Authors: Sevryugin Yu. V. , Chuvakorzin B. A.
Published: September 2023

The article discusses the strategy of indirect investment in cryptocurrency assets by compiling an investment portfolio of shares of public technology companies operating in the developing cryptocurrency market or investing in cryptocurrencies. When forming such a specialized portfolio, you can get the maximum level of profitability with a lower risk than when investing in cryptocurrencies directly, but only if you improve the methods of fundamental analysis. This is the goal set for achieving this research. The authors use the metrics of the world's largest analytical portals: GuruFocus, YahooFinance, Zacks, unfortunately, are not very popular among both Russian stock traders and portfolio investors. Each share, based on the values of the coefficients, is assigned a rating score, on the basis of which the coefficient of investment attractiveness is calculated. The purpose of portfolio diversification by sector and industry is to reduce non-systematic risk measured using the beta coefficient and the standard deviation of profitability. The results of calculations of the profitability and risk indicators of the formed portfolio are compared with the “benchmark” - the leading stock and cryptocurrency indices and conclusions are drawn about the feasibility of investing in this sector of the stock market.
THE PREFERRED APPROACH TO THE TRANSFORMATION OF THE PERSONNEL MANAGEMENT SYSTEM OF DEFENSE INDUSTRY ENTERPRISES WITH DIVERSIFICATION
Authors: Berkutova T. A. , Machova A. V.
Published: September 2023

Radical changes arising in connection with the reduction of the state defense order and the need for diversification at the enterprises of the military-industrial complex to provide the domestic market with high-tech dual-use and civilian products, initiate changes in the management of the personnel component of production by the personnel of the enterprise. Of particular importance are the issues of practical application of modern forms of personnel management, which make it possible to increase the economic efficiency of a diversified defense industry enterprise. Since various forms and types of diversification have their own personnel advantages and disadvantages, they must be taken into account when transforming the personnel management system at diversified defense enterprises. The types and forms of diversification that have developed in practice are considered and an attempt is made to identify the most widely used in the diversification of defense industry enterprises. The advantages and disadvantages of existing approaches to the transformation of personnel management (“system approach”, “process approach”, “functional approach”, “diagnostic approach”, “situational approach”, “project approach”) are analyzed and an attempt is made to justify an approach to the transformation of personnel management adequate to the specifics of a diversified enterprise. The authors consider the diagnostic approach to be the most preferable, which gives an idea of the strengths and weaknesses of a diversified enterprise, its potential capabilities, and provides an opportunity to develop a personnel management system that takes into account the specific features of the technology and organization of production of a diversified defense industry enterprise with various types and forms of diversification.
ACQUISITION OF THE RUSSIAN LANGUAGE BY KOREAN STUDENTS (technical program students)
Authors: Murinova E. E.
Published: September 2023

This article deals with traditional and modern methods, techniques of language pedagogy, connected with Russian lexicography and corpus linguistics. Contemporary tools of teaching Russian as a foreign language (new types of dictionaries, particularly ideographic and text corpuses) address issues related to unsystematic learning of the language, structuring the teaching process, enhancing students’ creativity and interests in the language. The author considers linguocultural aspect as central point of intercultural communication needed for linguistic persona development. It is reported that within language training programs for technical faculty students the following components are to be covered: gender aspects of communicative behavior reflected in verbal interaction, features of mind-set, cultural traditions of formal and informal communication. According to the author, this aim can be reached due to tasks on ranking in communication, contrastive-comparative analysis, working with lexicographic literature; texts of different styles and genres enable foreign students to learn lexical-phraseological system of the Russian language (theme groups; synonymic rows; antonymic pairs) more effectively, and pay attention to functional aspect of the language system.
PROSPECTS FOR THE DEVELOPMENT OF THE SETTLEMENT SYSTEM IN THE RUSSIAN FEDERATION
Authors: Oreshnikov V. V.
Published: September 2023

The article deals with the assessment of the attractiveness of the cities of the Russian Federation for the population and changes in the existing system of settlement. A brief review of strategic planning documents and scientific works in this area is given. In the framework of the study the methods of grouping and comparative analysis are used. The results of the assessment show that in the vast majority of cases the growth of urban population is provided at the expense of the migration component on the background of the natural population decline. Most of the cities with a high level of this indicator are concentrated in the central and southern parts of the country. The territorial location of the cities and proximity to the key economic centers of the country have a significant impact. In absolute terms, the largest population growth was recorded in Balashikha, Krasnodar, Sochi and Tyumen. There is an increasing polarization in the development of the Russian Federation. Changes in the age structure of the country's population will contribute to an increase in the demographic burden in the near future. The issue of competition of cities for labor resources and, in a broader sense, for human capital becomes more acute. In this regard, it is necessary to develop a methodology for identifying the factors that increase the attractiveness of cities and assess their impact on the demographic and migration behavior of different population groups.
CIRCULAR ECONOMY PRINCIPLES IN PROJECT MANAGEMENT IN CONSTRUCTION
Authors: Grigoryeva N. A.
Published: September 2023

The main definitions of the circular economy given by foreign and domestic authors in the framework of international studies are compared. It is assumed that the circular economy is one of the solutions to reduce pollution. Taking into account industry specifics definitions of the circular economyin construction definitions are considered. The main problems of the widespread use of the principles of the circular economy in construction are identified. It is determined that the circular economy can be carried out at the operational level (a certain production process), tactical (associated with all processes) and strategic (associated with the entire organization). Three main areas of practical application of the principles of the circular economy in construction are identified: recycling of used building materials (concrete, bitumen, rebar, asphalt, wood and glass products), the economic efficiency of reuse (faster, at the lowest expenses and lower total cost) and the principles energy efficiency (buildings with reduced energy consumption, environmental materials, energy efficient technologies, renewable energy resources and lean production) in the design, construction and operation of buildings. It is assumed that further systemic changes in construction will concern the industrial production of materials from recycled resources, smart urban planning, the sharing of residential and office space, energy efficient construction.
STATISTICAL DATA ON THE COMPATIBILITY OF THE VERB ‘НАЧАТИ’ IN RUSSIAN СHRONICLES OF THE XIV-XV CENTURIES
Authors: Vernyaeva R. A.
Published: September 2023

This article provides a description of the compatibility features of the verb ‘начати’ in the Old Russian language. The material for this study was electronic transcriptions of the most ancient Russian Chronicles, published on the portal “Manuscript: Slavic Written Heritage”. Within the framework of this work, a quantitative-statistical research method was used, which allows not only to determine the number of occurrences of a particular language unit, but also to statistically substantiate the combinatorial nature of the components with each other. To obtain statistical data on the compatibility of the verb ‘начати, the module of n-grams of the IAS “Manuscript” was used, which makes it possible to identify text combinations with a different number of components and analyze the frequency of functioning of language units in texts. As part of this work, we used the T-score measure, which allows us to determine the most frequent combinations, as well as to identify how non-random the strength of the connection between words in a phrase is. The analysis of statistical data confirms the effectiveness of the use of association measures when working with the Old Russian text. It was revealed that the verb ‘начати’ is most often combined with the infinitive of imperfective verbs. The dictionaries used in the work demonstrate a fairly wide semantics for the verb ‘начати’. In the chronicle text, we recorded the functioning of this unit in only two meanings.
DIGITAL TECHNOLOGIES AND MATHEMATICAL METHODS OF ANALYSIS
Authors:   Ural State University of Economics, Rozhkov Evgeny
Published: September 2023

The development of today's science and technology not only encourages scientists to develop a new product (product) or services for users, but also to use existing processes in the economy, taking into account mathematical methods of analysis. The introduction of digital technologies in all areas of activity has made it possible to draw the attention of managers at all levels to apply mathematical methods. The use of digital platforms in the economy is inseparable from mathematical methods. The methodology used by the authors of the article characterizes the general scientific knowledge of the existing problems in the development of a digital platform model. The study of the sequence of digitalization determined initially the formation of models of complex and synthetic indicators, and later the analysis of the data obtained. The materials used in the analysis, received from the territorial body of statistics, showed the presence of current problems in economic processes. for the most part, on the territory of our country, they depend on imported components and on foreign software and on the programming language. The conclusions presented in the article make it possible to understand the need to use mathematical methods of analysis.
THE SOCIAL ROLE OF DIGITALIZATION IN THE FORMATION OF A UNIVERSAL CULTURE AND ITS IMPACT ON YOUNG PEOPLE
Authors:   Bryansk State Academician I.G. Petrovski University, Lifanova Tatiana , Krivonosova Zhanna ,   Bryansk State Academician I.G. Petrovski University, Yerokhov Mikhail ,   Bryansk State Academician I.G. Petrovski University
Published: September 2023

The article deals with the problems included in the scientific field of the sociology of culture. These issues contribute to the consideration of the role of digitalization in the modern world and its impact not only on society as a whole, but, in particular, on such a socio-demographic group as youth. VTSIOM data on the impact of digitalization on the younger generation were analyzed, various aspects of this influence were considered and conclusions were drawn. The positive and negative sides of this phenomenon are also highlighted. With the development of Internet communications, one should not forget about the emergence of such a thing as Internet addiction, which is given much attention in the work as «diseases of the XXI century». The analysis of a social experiment conducted on an entertainment platform on the Internet was also carried out.
SOCIOLOGICAL STUDY OF POLITICAL IMAGE: INDICATORS AND MEDIA PORTRAIT
Authors:   Bryansk State Academician I.G. Petrovski University, Melnikov Sergey , Emelyanov Victor ,   Bryansk State Academician I.G. Petrovski University, Poturaev Dmitry ,   Bryansk State Academician I.G. Petrovski University
Published: September 2023

In the article, the authors consider the image of such a political figure as Vladimir Wolfovich Zhirinovsky. It is proved that sociological research contributes to a more successful formation of the image of a politician. The article substantiates and explores the image indicators of a charismatic politician by analyzing scientific works devoted to the image of this personality, by monitoring a number of news publications with mention of V.V. Zhirinovsky, which allows us to determine the content of publications through the following types of connotations - positive, neutral and negative. The article creates a certain media portrait, concludes about the effectiveness of techniques for creating a positive image and the possibility of using these technologies for other political figures.
Recovering Assets at an International Anti-Corruption Court
Authors: Birkett Daley
Published: September 2023

Writing in 2022, Mark Wolf, Richard Goldstone, and Robert Rotberg detail a proposal for the establishment of an International Anti-Corruption Court (IACC), a plan that has received some diplomatic support from Canada, Ecuador, and the Netherlands. The focus of this article rests on asset recovery in the context of the proposal. Among the questions that the article considers are: (i) What might the drafters of a statute for a prospective IACC learn from the experience of the International Criminal Court in relation to asset recovery? and (ii) How might an IACC’s focus on corruption serve to heighten the importance of asset recovery and/or create special challenges in this sphere of the proposed institution’s operations?
Practical Experiences from Big History: Middle School in Taiwan
Authors:   Mingdao High School, Taichung City, Taiwan, Wang Albert T.
Published: September 2023

From the Big Bang to the recent development of human civilization, we are exploring the future and examining the past. Big History includes knowledge about the universe and the composition of the chemical elements, which represent the macrocosm and microcosm for the whole picture. In the frame of Big History, we connect everything that seems irrelevant to the relevant, bringing it all together. At Mingdao High School, we focus on multi-performance and development, so we introduced a big-history course to our tenth-grade students. Instead of accepting knowledge passively in a classroom, we train them by cultivating their concept-creative ability and problem-solving skills. For such a course, it represents an unprecedented step forward in their lives.
UNDERSTANDING INTELLECTUAL PROPERTY RIGHTS IN THE INDONESIAN TRADING BUSINESS
Authors: Maghfirah Nurul , Zaviera Siti , Alghazy Daffa , Fahmi Chairul
Published: September 2023

This article aims to find out the concept of Intellectual Property Rights (IPR) in Indonesia and its application in business ventures. In general, Indonesia has recognised IPR and has passed a number of laws related to IPR protection. This research uses a literature approach method, where data is obtained from secondary sources, both from books, articles and various references related to this research. The results show that the application of IPR in Indonesia is still experiencing various problems, where many IPR results are violated. Conversely, law enforcement against IPR violations is still very weak. This is inseparable from the scope of IPR which is categorised as part of civil law. This means that if no one reports and feels harmed by the IPR violation, then the violation is not followed up or handled by the authorities.
Creating a special software module to assess the territory’s spatial development indicators
Authors: Chernykh E.G. , Merkurieva K.R.
Published: September 2023

The article deals with the problem of assessing the spatial development of a complex entity. To solve the problem, the authors proposed the development of a software module using MapBasic for GIS MapInfo, which greatly simplifies and systematizes the user`s work to form an initial database of the territory spatial development indicators. The accumulated and systematized data form them, and they enable clear demonstrating the results of correlation analysis for the Yamal-Nenets Autonomous Okrug, HMAO and the South of the Tyumen Oblast, RF. The program module implements the formation of the current indicator’s evaluation model and the forecast of the settlement lands cadastral value’s specific indicator based on multilevel filtering of selected pairs of indicators. The authors note the possibility of integrating the developed module into the existing domestic software of geoinformation systems for the convenience of reorienting projects from one software to another
Oferta do Profuncionário
Authors: Pereira Helen , Viana da Silva Ruth Aparecida , Ferreira de Azara Filho Milton
Published: September 2023

Toda política voltada para a formação de trabalhadores/as da educação básica encontra-se vinculada a sujeitos/as concretos/as, pertencentes a um contexto histórico no qual concepções de educação e trabalho se articulam a objetivos específicos. A formação inicial e continuada de funcionários/as da educação foi referendada pelo Decreto nº 8.752, de 9 de maio de 2016, instituindo a Política Nacionalde Formação dos Profissionais da Educação Básica. Entendendo que a formação é condição sine qua non para a valorização de funcionários/as, o presente texto apresenta as experiências do InstitutoFederal de Educação, Ciência e Tecnologia de Goiás com o Programa Profuncionário. Dada sua importância e abrangência para formação, reconhecimento e valorização da categoria, enfatiza-se a necessidade de endossar a luta por valorização e efetivação de políticas de formação inicial e continuada que contemplem as áreas de atuação de trabalhadores/as no espaço escolar.
Proximity Extension assay-based proteomics studies in neurodegenerative disorders
Authors: Arioz Burak , Cotuk Aysen , Yaka Cansu , Genc Sermin
Published: September 2023

Neurodegenerative diseases impact the structure and operation of the
nervous system, causing progressive and irreparable harm. The absence of
distinguishable symptoms in the early stages of neurodegenerative
diseases makes diagnosis challenging. Additionally, it can be difficult
to pinpoint the precise neurodegenerative disorder affecting a patient
as the symptoms of these conditions frequently overlap. Numerous studies
have shown that pathological changes occur years before clinical signs
appear. Therefore, it is crucial to discover blood-based biomarkers for
neurodegenerative diseases for easier and faster diagnosis. Proximity
Extension Assay is a unique proteomics method that uses antibodies
linked to oligonucleotides for quantifying proteins with real-time PCR.
Proximity Extension Assay can identify even low-quantity proteins using
a small volume of specimens with increased sensitivity compared to
conventional methods. In this article, we reviewed the employment of
Proximity Extension Assay technology to detect biomarkers or protein
profiles for several neurodegenerative diseases.
Chemical Sensing of Common Microorganisms Found in Biopharmaceutical Industries Using Mid-Infrared Laser Spectroscopy and Multivariate Analysis
Authors: Hernandez-Rivera Samuel P , Carrión-Roca Wilmer , Colón-Mercado Annette M. , Colón-González Francheska M. , Castro-Suarez John R. , Caballero-Agosto Edwin R. , Centeno José A. , Ríos-Velázquez Carlos
Published: September 2023

We report on the spectroscopic investigation of common bacteria
encountered in biopharmaceutical industries with spectroscopic
definition and specificity using mid-infrared laser spectroscopy. This
study describes the detection of three different bacteria species using
quantum cascade laser spectroscopy coupled to a grazing angle probe
(QCL-GAP). Stainless steel substrates were used as support for the
bacterial samples. QCL-GAP spectroscopy was assisted by multivariate
analysis (MVA) to assemble a powerful spectroscopic technique with
classification, identification, and quantification resources. The
bacterial species analyzed, Staphylococcus aureus,
Staphylococcus epidermidis, and Micrococcus luteus, were
used to challenge the technique’s capability to discriminate
microorganisms from the same family. Principal component analysis and
partial least squares-discriminant analysis differentiated between the
bacterial species using QCL-GAP. Spectral differences in the bacterial
membrane were used to determine if these microorganisms were present in
the samples analyzed. Results herein provided effective discrimination
for the bacteria under study with high sensitivity and specificity
values.
Building living systematic reviews and reporting standards for comparative microscopic analysis of white diseases in hard corals.
Authors: Page Charlotte , Anderson Ella , Ainsworth Tracy
Published: September 2023

1. Over the last four decades coral disease research has continued to
provide reports of disease states, the occurrence and severity of
disease outbreaks, and associated disease signs however nomenclature and
protocols for microscopic disease descriptions have yet to be
implemented. Histopathology using systematic protocols is a gold
standard for the microscopic assessment of diseases in veterinary and
medical research. Increasing disease outbreaks on coral reefs as human
impacts intensify highlights the need to also establish standardised
diagnostic terminology and methodology for coral disease research. 2.
Here we apply a systematic approach to collating, reviewing, and
evaluating histopathological methods used to study white diseases in
hard coral taxa and map research effort in this field spanning study
design, sample processing and analysis in the 33 publications identified
between 1984 and 2022. 3. We find that studies to-date have not
uniformly detailed methodologies, and terminology associated with
histopathological reporting and disease description is inconsistent
between studies. Combined these limitations reduce study repeatability,
limiting the uptake of histopathology in coral disease research and the
capacity for researchers to compare disease reports. 4. A primary
outcome of this study is revision of the most widely used terminology
applied to coral tissue and development of recommendations for
standardised reporting procedures with the aim of increasing
accessibility and uptake of histopathology in addition to allowing for
ongoing comparative analysis through living systematic reviews for the
coral disease field.
Financial conflicts of interest among infectious disease journal editors in the United States
Authors: Murayama Anju
Published: September 2023

Objective

There are widespread financial relationships between journal editors and
healthcare industry in the United States (US) across specialties. These
relationships could be conflicts of interest among editors: however, no
studies have been assessed the extent of the relationships in infectious
diseases.

Methods

Using the Open Payments Database between 2014 and 2022, financial
relationships between the healthcare industry and all US-based physician
editors of the six clinical infectious disease journals with the highest
impact factors were evaluated. Proportion of the editors with payments
and payment amounts to the editors were calculated.

Results

Of the 82 eligible US physician editors, 61 (74.4%) and 45 (54.9%)
received non-research payments from the healthcare industry for the
periods 2014-2022 and 2020-2022, respectively. Meanwhile, 22.4% and
40.3% received direct research payments and associated research funding
over the nine years. The total payment amounts to the editors were
$3,996,131 in non-research payments, $933,813 in direct research
payments, and $39,394,410 in associated research funding. The majority
of US physician editors received non-research payments between 2020 and
2022 in the Clinical Microbiology and Infection, Clinical Infections
Diseases, Journal of Travel Medicine, and Journal of Infectious
Diseases. Only two journals had conflicts of interest policies for their
journal editors available on the journal webpage. Additionally, none of
the journals disclosed the editors’ conflicts of interest.

Conclusions

This study found that the majority of the US-based physician editors of
high-impact infectious disease journals received payments from the
healthcare industry. Additionally, these financial conflicts of interest
among the editors were not publicly disclosed.
Integrative taxonomy of Ceratozamia mexicana Brongn. (Zamiaceae) complex from a phylogeographic perspective
Authors: Medina-Villarreal Anwar , Gonzalez-Astorga Jorge , Monteros Alejandro Espinosa de los
Published: September 2023

In recent years, there has been a growing interest in research on
Ceratozamia cycads, which has resulted in a significant increase in our
understanding of their diversity. However, species complexes that have
been tackled through integrative methodologies have exhibited a bias
towards morphology over genealogy. Thus, there arises the necessity to
reevaluate the Ceratozamia mexicana species complex using
phylogeographic tools. For this purpose, we have employed the
integrative taxonomic protocol Schlick-Steiner et al. (2010) put forth.
This protocol delineates species as testable hypotheses, incorporating
lines of evidence within a reproducible and falsifiable framework. The
evaluated data encompassed (i) phylogenetic and molecular variance
analyses, (ii) multivariate morphometric analyses, and (iii) analysis of
climatic niches. Out of the 196 individuals from 13 studied populations,
seven monophyletic groups were recovered. These groups were
substantiated by multivariate morphometric analysis, revealing
significant differences, and were further validated by niche divergence.
These results underscore a ‘whole agreement’ across the three
disciplines, thus providing robust support for acknowledging the species
as distinct lineages. The species delimited by these lineages,
encompassing phylogenetic, morphological, and environmental factors,
correspond to C. brevifrons, C. delucana, C. decumbens, C. mexicana, C.
moretti, C. tenuis, and a novel cryptic species, sister to the latter.
Finally, this genealogical characterization will offer utility in the
future for uncovering the genetic identity of the holotype of the type
species within the Ceratozamia genus.
Rearranging Fluorescence-Magneto Spatiality for “Win-Win” Dual Functions to Enhance Point-of-Care Diagnosis
Authors: Su Yu , Chen Xirui , Huang Huan , Wu Yuhao , Shen Xuan-ang , Lin Xiangkai , Sun Kun , Fan Xiao-Yong , Huang Xiaolin , Xiong Yonghua
Published: September 2023

Fluorescent-magneto nanoemitters have gained considerable attention for
their applications in mechanical controlling-assisted optical signaling.
However, the incompatibility between magnetic and fluorescent components
often leads to functional limitations in traditional
magneto@fluorescence nanostructure. Herein, we introduce a new
compact-discrete spatial arrangement on a “fluorescence@magneto”
core–shell nanostructure consisting of a close-packed
aggregation-induced emission luminogen (AIEgen) core and a discrete
magnetic shell. This structural design effectively eliminates the
optical and magnetic interferences between the dual components by
facilitating AIEgens loading in core region and reducing the magnetic
feeding amount through effective exposure of the magnetic units.
Thereby, the resulting magneto-AIEgen nanoparticle (MANP) demonstrates
“win-win” performances: (i) high fluorescent intensity contributed by
AIEgens stacking-enhanced photoluminescence and reduced photons loss
from the meager magnetic shell; (ii) marked magnetic activity due to
magneto extraposition-minimized magnetic shielding. Accordingly, the
dual functions-retained MANP provides a proof of concept for
construction of an immunochromatographic sensing platform, where it
enables bright fluorescent labeling after magnetically enriching and
separating procalcitonin and lipoarabinomannan in clinical human serum
and urine, respectively, for the clinical diagnosis of bacterial
infections-caused inflammation and tuberculosis. This study not only
inspires the rational design of magnetic-fluorescent nanoemitter, but
also highlights promising potential in magneto-assisted point-of-care
test and biomedicine applications.
Awaiting the demise of the liberal order: Historicising the crisis of liberalism
Authors: Markovic Vukan
Published: September 2023

This review article analyses the merits and shortcomings of three recent
works by Matthew Rose, Peter Turchin, and Krishnan Nayar about the crisis in
Western liberal democracies and liberalism. By exploring the intellectual
and economic causes of the crisis, these authors are trying to establish a
historical model that would explain the current crisis through a
comprehensive account of the development of Western societies. In doing so,
they identify the detrimental role of the elites and the growing
inequalities as the major factor that historically contributes to the demise
of liberal values, endangering democratic rule of law. Therefore, the three
books are a warning that the demise of the liberal order will bring about
the resurgence of right-wing authoritarianism. However, all three authors
avoid discussing the nature of liberalism as the dominant ideology in the
West. This article presents a criticism of such models, arguing that any
discussion of the crisis of liberalism which avoids considerations about
liberalism itself and liberal ideologies, necessarily fails to encapsulate
the actual experience of the crisis. In addition, these models limit
history?s usefulness in interpreting the causes of the crisis and preventing
its consequences.
Does Kant’s maxim ‘ought-implies-can’ apply if the principle of alternate possibilities does not?
Authors: Prasevic Nedzib
Published: September 2023

Frankfurt?s critique of the principle of alternate possibilities led to a reexamining of many of the conditions that were rooted in the principle. One of these includes Kant?s famed maxim ?Ought-implies-can?. Since the alternate possibilities principle underscores the condition that is required for the subject to be morally responsible (could have done otherwise condition), the maxim also implies the condition?s validity also in situations where it is met and provides the basis for the attributiveness of morally relevant qualities. Although Frankfurt?s example showed that the presence of moral responsibility does not require the validity of the alternate possibilities principle - the condition of the possibility of acting differently need not be met - then even the attributiveness of moral qualities, in the way that the maxim implies, cannot be applied in situations where the subject is responsible, even though they could not have done otherwise. Frankfurt, however, refuses to draw this conclusion and believes that even under the conditions set forth, the maxim can apply. The provocative claim challenges Frankfurt-type compatibilists, and the paper examines whether it is founded, in addition to what consequences can be drawn pertaining to Kant?s maxim?s validity. The conclusion - contrary to Frankfurt?s initial optimism - is that in a world where causal determinism applies and where the alternate possibilities principle does not, although the subject may be morally responsible, their responsibility cannot be grounded in deontological reasoning.
Simultaneous BPSK classical communication and continuous variable quantum key distribution with a locally local oscillator regenerated by optical injection phase locked loop
Authors: Khaksar Zeinab Sadat , Bahrampour Alireza
Published: September 2023

This paper proposes a scheme for simultaneous classical communication and continuous variable quantum key distribution with a true local oscillator. In this scheme, the emitter’s laser, after binary phase-shift keying (BPSK) modulation, is multiplexed in polarization with the quantum signal and sent to the receiver. After BPSK demodulation and correction, this signal is used for local oscillator regeneration by an optical injection phase-locked loop method. Comparing the effective noise sources in this scheme with typical local local oscillator schemes revealed that continuous variable quantum key distribution (CV-QKD) with a true local oscillator based on the optical injection phase-locked loop encounters lower levels of noise in comparison to the pre-existing genuine local oscillator CV-QKDs.
Food Fish, Commercial Fish, and Fish to Support a Moderate Livelihood: Characterizing Aboriginal and Treaty Rights to Canadian Fisheries
Authors: C. Harris Douglas , Millerd Peter
Published: September 2023

The Aboriginal peoples of Canada stand in a different legal relationship to the fisheries than non-Aboriginal Canadians. They do so by virtue of a long history with the fisheries that precedes non-Aboriginal settlement in North America, and because of the constitutional entrenchment of Aboriginal and treaty rights in Canadian law. This article describes the characterizations of Aboriginal and treaty rights to fish in Canadian law and discusses what it means for rights characterized in terms of food fishing, commercial fishing, and fishing to support a moderate livelihood, to receive constitutional protection. The article then problematizes these characterizations and suggests that the simplest and broadest characterization, that is, of a right to fish without restriction as to purpose or use of fish, best coincides with the goals of effective management and fair distribution.Keywords: Fisheries, Indigenous people, Aboriginal and treaty rights, Canada.Citation: Arctic Review on Law and Politics, vol. 1, 1/2010 p. 82–107. ISSN 1891-6252