bluuebunny/crossref_metadata_2025 huggingface dataset:
Aberrant Resting-State Regional Activity in Patients with Postpartum Depression
Authors: Zhang Shufen , Li Bo , Liu Kai , hou xiaoming , Zhang Ping
Published: October 2021

The aim of this study is to investigate the alterations of individual local connectivity by regional homogeneity (ReHo) in patients with postpartum depression (PPD) during resting state, and their potential correlations with clinical severity. Thirty patients with PPD and twenty-nine matched healthy postpartum women within 4 weeks after delivery were recruited and performed resting-state functional magnetic resonance imaging (fMRI) scans. The ReHo value was computed as Kendall’s coefficient of concordance (KCC) in the present study, and intergroup differences in the voxel manner were analyzed. Correlations between ReHo values and clinical variables were also analyzed. Compared with healthy postpartum women, patients with PPD exhibited significantly higher ReHo in left precuneus and right hippocampus. ReHo was significantly lower in left dorsolateral prefrontal cortex (dlPFC) and right insula. Furthermore, ReHo values within the dlPFC negatively correlated with the Edinburgh postpartum depression scale (EPDS) score. The ROC curve analysis showed that the area under the curve (AUC) of the above four brain regions are all over 0.7. This study provided evidences of aberrant regional functional activity within brain regions involved in the maternal care network in PPD, and may contribute to the further understanding of neurobiology underlying PPD.
Multifunctional Carbonized Nanogels to Treat Lethal Acute Hepatopancreatic Necrosis Disease
Authors: Yen Shao-Chieh , Mao Ju-Yi , Lin Hung-Yun , Huang Huai-Ting , Harroun Scott G. , Nain Amit , Chang Huan-Tsung , Lin Han-You , Chen Li-Li , Huang Chih-Ching , Lin Han-Jia
Published: October 2021

Background: Shrimp aquaculture has suffered huge economic losses over the past decade due to the outbreak of acute hepatopancreatic necrosis disease (AHPND), which is mainly caused by the bacteria Vibrio parahaemolyticus (V. parahaemolyticus) with the virulence pVA1 plasmid, which encodes a secretory photorhabdus insect-related (Pir) toxin composed of PirA and PirB proteins. The Pir toxin mainly attacks the hepatopancreas, a major metabolic organ in shrimp, thereby causing necrosis and loss of function. The pandemic of antibiotic-resistant strains makes the impact worse. Methods: Mild pyrolysis of a mixture of polysaccharide dextran 70 and the crosslinker 1,8-diaminooctane at 180 ℃ for 3 h to form carbonized nanogels (DAO/DEX-CNGs) through controlled cross-linking and carbonization. The multifunctional therapeutic CNGs inherit nanogel-like structures and functional groups from their precursor molecules. Results: DAO/DEX-CNGs manifest broad-spectrum antibacterial activity against Vibrio parahaemolyticus responsible for AHPND and even multiple drug-resistant strains. The polymer-like structures and functional groups on graphitic-carbon within the CNGs exhibit multiple treatment effects, including disruption of bacterial membranes, elevating bacterial oxidative stress, and neuralization of PirAB toxins. The inhibition of Vibrio in the midgut of infected shrimp, protection of hepatopancreas tissue from Pir toxin, and suppressing overstimulation of the immune system in severe V. parahaemolyticus infection, revealing that CNGs can effectively guard shrimp from Vibrio invasion. Moreover, shrimps fed with DAO/DEX-CNGs were carefully examined, such as the expression of the immune-related genes, hepatopancreas biopsy, and intestinal microbiota. Few adverse effects on shrimps were observed. Conclusion: Our work proposes brand-new applications of multifunctional carbon-based nanomaterials as efficient anti-Vibrio agents in the aquatic industry that hold great potential as feed additives to reduce antibiotic overuse in aquaculture.
Characteristics and Clinical Significance of Lipid Metabolism in Patients with Gastrointestinal Stromal Tumor
Authors: Liu Xiaoling , Liu Bende , Hu Jun
Published: October 2021

Objective To investigate the characteristics and clinical significance of serum lipids in patients with gastrointestinal stromal tumor (GISTs).Methods The clinical and pathological data of 694 cases of GIST patients in Liyuan hospital and Union hospital from 2012 to 2016 were retrospectively analyzed. To compare the differences of blood lipid levels in patients with different risk levels.Results There was no significant correlation between preoperative lipid profile and some clinical features, including age, tumor frequency, CD117 or SMA positive or negative, and Ki67% < 5% or not (P ＞0.05). LDL-C, HDL-C and CHOL were significantly higher in women than men (P < 0.05). Compared to patients with tumor size over 5cm, TG, HDL-C and CHOL were significantly higher in those under 5cm (all P < 0.05). LDL-C, HDL-C and CHOL were higher in CD34 positive subjects than in negative ones. TG in the DOG-1 positive group was higher than that in negative one (P < 0.05). HDL-C was lower in S-100 positive subjects than in S-100 negative subjects (P < 0.05). Lipids indexes were correlated with the risk grade and tumor site of GISTs (P < 0.05). TG/HDL-C was significantly different in patients with GIST with different tumor sites, CD34 and DOG-1 positive or not (P < 0.05).Conclusion The clinical and pathological characteristics of the patients with GIST are closely related to the level of blood lipids. Blood lipids level can help judge benign or malignant of GIST to a certain extent.
The Economic Fitness of Nations in Value Added. 2000-2014
Authors: Cervantes-Martinez Rosario , Villaseñor-Becerra Jorge
Published: October 2021

In this paper, we explore the Economic Fitness (EF) indicator from the World Bank Database that measures nations' level of international competitiveness. At the same time, using input-output tables, we present our estimations of this new metric, replacing the revealed comparative advantages (RCA) from exports in gross value with an estimate of RCA from exports in domestic value-added (DVA). We find that between 1995 and 2015, there is a positive relationship between Economic Fitness and per capita GDP for low and middle-income countries. Besides, from 2000 to 2014, there has been a widening gap between global exports in gross value and exports in value-added; we also show that the estimations of the EF using the domestic value-added content of exports change significantly. Suggesting that, given the increasing levels of productive links at the international level, the competitiveness of nations is also conditioned by the way they participate in global production networks.
Non-intrusive Nonlinear Model Reduction via Machine Learning Approximations to Low-dimensional Operators
Authors: Bai Zhe , Peng Liqian
Published: October 2021

Although projection-based reduced-order models (ROMs) for parameterized nonlinear dynamical systems have demonstrated exciting results across a range of applications, their broad adoption has been limited by their intrusivity: implementing such a reduced-order model typically requires significant modifications to the underlying simulation code. To address this, we propose a method that enables traditionally intrusive reduced-order models to be accurately approximated in a non-intrusive manner. Specifically, the approach approximates the low-dimensional operators associated with projection-based reduced-order models (ROMs) using modern machine-learning regression techniques. The only requirement of the simulation code is the ability to export the velocity given the state and parameters; this functionality is used to train the approximated low-dimensional operators. In addition to enabling nonintrusivity, we demonstrate that the approach also leads to very low computational complexity, achieving up to $10^3\times$ in run time. We demonstrate the effectiveness of the proposed technique on two types of PDEs.
Curcumin and Zinc Co-Supplementation Along With a Loss-Weight Diet Can Improve Lipid Profiles in Subjects with Pre-Diabetes: A Multi-Arm, Parallel-Group, Randomized, Double-Blind Placebo-Controlled Phase 2 Clinical Trial
Authors: Karandish Majid , Mozaffari-khosravi Hassan , Mohammadi Seyed Mohammad , Cheraghian Bahman , Azhdari Maryam
Published: October 2021

Background: Diabetes is one of the major public health concerns. Pre-diabetes can increase the risk of developing some non-communicable diseases such as type 2 diabetes. Given the increasing trend of pre-diabetes, it is critical to control it and prevent its complications. Curcumin is a major bioactive component of turmeric. Zinc is an antioxidant nutrient. The present trial aimed to evaluate the effect of curcumin and zinc co-supplementation along with a loss-weight diet on serum lipid profiles in overweight or obese patients with pre-diabetes.Methods: Eighty-four participants were randomized to four groups (curcumin (500 mg/day), zinc (30 mg/day), “curcumin & zinc”, and placebo) for 90 days. Serum total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), non-HDL, HDL/LDL ratio, weight, BMI, waist circumstance (WC), hip circumstance (HC), physical activity (PA) and dietary intake were determined pre and post-intervention. This study will be conducted at Yazd Diabetes Research Clinic, Shahid Sadoughi University of Medical Sciences.Results: Totally, 82 participants were included in the final analysis. After the adjusted PA effect, changes in serum TG (adjusted p = 0.001), LDL (adjusted p = 0.035), non-HDL (adjusted p =0.003), HDL/LDL ratio (adjusted p =0.002), and HDL (adjusted p < 0.0001) revealed a significant difference between the groups. However, the changes in weight (adjusted p = 0.004) and BMI (adjusted p = 0.006) were significant but the changes in dietary intake, PA, WC, and HC were non-significant (adjusted p ≥ 0.05). Despite that there was a significant difference for post-intervention HDL levels (adjusted p = 0.016), other lipid profiles showed no significant difference (adjusted p ≥ 0.05).Conclusion: The beneficial effects of “curcumin & zinc” co-supplementation was reported for the changes of some lipid profiles (TG, LDL, HDL, non-HDL, and HDL to LDL ratio), BMI, and weight with no positive effects on TC, dietary intake, PA, WC, and HC. Therefore, it may play a potential role in the prevention of macro and microvascular complications.Trial registration: The project is a registered clinical trial (Registration number: IRCT20190902044671N1, Iranian Registry of Clinical Trials (IRCT), registered October 11, 2019.
WITHDRAWN: The Two Mono-Carbonyl Curcumin Analogs, PGV-1 and CCA-1.1: The Chemopreventive Activity Against DMH-Induced Colorectal Cancer Rat and Proteins Target Candidate Involved
Authors: Wulandari Febri , Ikawati Muthi' , Kirihata Mitsunori , Widyarini Sitarina , Kato Jun-Ya , Meiyanto Edy
Published: October 2021

Pentagamavunone-1 and its newest derivatives, CCA-1.1, possess an outstanding cytotoxic activity against several cancer cell lines, especially colorectal cancer. We are continuing to explore the anti-colorectal cancer properties of PGV-1 and CCA-1.1 against DMH-induced colorectal cancer rats and expound the potential protein target in colorectal adenocarcinoma. We utilized DMH 60 mg/kg (subcutaneous injection once a week for 16 weeks) to induce colorectal cancer. PGV-1 and CCA-1.1 at 10 and 20 mg/kg (orally twice a week for 16 weeks) were co-administered with DMH. The WBC count increased in a single DMH group and was countered by co-administration of PGV-1 and CCA-1.1, but no significant differences in RBC. Single DMH treatment for 16 weeks resulted in 80% adenocarcinoma. In contrast, co-administration with PGV-1 and CCA-1.1 suppressed most of the carcinogenic characteristics and symptoms of the pre-malignancy condition. Furthermore, bioinformatics analysis showed that CCA-1.1 has more specific targets than PGV-1, including CDK1, CDK2, MMP3, MMP14, and CYP3A4, which regulate the cell cycle arrest, cancer cell migration, and xenobiotic metabolism, respectively. Interestingly, CCA-1.1 targets CYP3A4, which possibly interrupts DMH metabolism and prevents the initiation of DMH-colorectal carcinogenesis. In conclusion, CCA-1.1 performed better chemopreventive effects against DMH colorectal cancer and might replace PGV-1 to be promoted as a more effective anti-colorectal cancer agent.
The Traditional Medicine Practitioner’s Concept of Cancer, Herbal medicine use and the Patients Perceived benefits (Clinical outcomes) in Selected Districts of Central Uganda: An Exploratory Study Protocol
Authors:   John Baptist Asiimwe1, Nagendrappa Prakash B. , Atukunda Esther C. , Nambozi Grace , Tolo Casim U. , Ogwang  , Sarki Ahmed M. , Kamatenesi Maud M.
Published: October 2021

Background: In sub-Saharan Africa, herbal medicine for cancer is dispensed by traditional medicine practitioners (TMPs) to a large extent, who may not have adequate knowledge about the disease and this has been found to contribute to the late presentation of cancer patients to clinics and hospitals leading to poor patient outcomes.Aim: This study will investigate the traditional medicine practitioner's concept of cancer, its care, herbal medicine use, and the patients' perceived benefits (clinical outcomes) in selected districts of Central Uganda.Methods: This study will use a convergent parallel mixed-method design. TMPs claiming to treat cancer, with at least 10 years of experience will be recruited and interviewed about their understanding of cancer as a disease (grounded theory design) and the herbs used in cancer treatment (ethnobotanical survey). We will also conduct a prospective observational study to obtain the data on the perceived clinical outcomes of using herbal medicine. Adult patients (>18years) with a medical diagnosis of cancer signposted by TMPs will be recruited and followed up at baseline, 3, and 6 months. Study outcomes will include a change in the quality of life score, cancer symptoms score, perceived benefits score, and adverse reactions. The researcher will analyze qualitative data using Open, axial, selective coding techniques. We will analyze the quantitative data using descriptive statistics and results presented in frequencies, percentages and measures of central tendency (mean) where applicable. Additional analyzes such as bivariate (paired t-test and one-way repeated measures ANOVA), and multivariate (linear mixed effects model) analysis for the repeated measures data shall be undertaken to analyze the prospective observational data. P- Values of <0.05 will be considered statistically significant.Discussion: This study will aid researchers in further understanding the TMPs' conceptualization of cancer, how that links to the treatment dispensed to their patients, and ultimately the patient-perceived outcomes.
NONLINEAR ROLLING STABILITY AND CHAOS RESEARCH OF TRIMARAN VESSEL WITH VARIABLE LAY-OUTS IN REGULAR AND IRREGULAR WAVES UNDER WIND LOAD
Authors:   Marine Design & Research Institute of China, China, 200011, Zhang Yihan , Wang Ping , Liu Yachong , Hu Jingfeng
Published: October 2021

The trimaran vessel rolls strongly at low forward speed and may capsize in high sea conditions due to chaos and loss of stability, which is not usually considered in conventional limit-based criteria. In order to perfect the method of measuring roll performance of trimaran, a set of nonlinear roll motion stability analysis method based on Lyapunov and Melnikov theory was established. The nonlinear roll motion equation was constructed by CFD and high-order polynomial fitting method. The wave force threshold of rolling chaos in regular waves is calculated by Gauss-Legendre numerical integration method. The limited significant wave height of rolling chaos in random sea conditions is deduced by the phase space transfer rate, and the complex effect of wind load is superposed in the calculation. The influence of trimaran configuration on the roll system is analyzed through the state differentiation of homoclinic and heteroclinic orbit in phase portrait. The calculation of the maximum Lyapunov exponent further verified the applicability of Melnikov method, and the topological structure change of gradual failure of the rolling system is analyzed by the erosion of safe basin. The complex changes of the nonlinear damping coefficient and the nonlinear restoring moment coefficient caused by the change of the transverse lay-outs between the main hull and side hull have a significant influence on chaos and stability, and the existence of wind load has a certain weakening effect on the stability and symmetry of the system. The conclusion also further indicates the importance of the lay-outs to the dynamic stability of the trimaran vessel, which is significant for its seakeeping design.
Investigating the Benefits of Integrated Anatomy Instruction: A Cognitive Load Theory Perspective
Authors: Talip Saiful Bahri , Mohd Ismail Zul Izhar , Hadie Siti Nurma Hanim
Published: October 2021

Declining anatomy knowledge of junior doctors has been linked to clinical error judgement and medicolegal litigation. To overcome the problem, anatomy educators have introduced many teaching initiatives during undergraduate study that might promote anatomy knowledge acquisition and retention, including anatomy teaching using integrated instruction. Anatomy instruction can be integrated in terms of its contents and teaching approach. Learning from integrated anatomy instruction allows students to relate anatomy subjects with different subdisciplines and to comprehend related clinical context for future application. On the other hand, the integrated approach for anatomy teaching caters to different types of learning styles, therefore ensuring optimal learning. Nevertheless, causal relationships between integrated anatomy instruction and student learning has never been explicitly explored. Hence, this article aims to unearth the elements of integrated anatomy teaching that promote learning through instructional design theory, namely, cognitive load theory (CLT).
Flipping the “Learning Skills” Course during COVID-19: A Mixed-Modality Study
Authors: Akram Ashfaq , Sattar Kamran , Ahmad Tauseef , Abdulghani Hamza M. , John Jennesse , Yusoff Muhamad Saiful Bahri
Published: October 2021

The purpose of this study was to compare the male and female medical students’ perceptions of the flipped classroom (FC) using the Zoom online platform during the COVID-19 pandemic. A mixedmodality study proceeded for first-year undergraduate medical students (n = 149). Three topics (learning how to learn, stress management and doctor-patient communication) were flipped using the Zoom platform. Following the flipping, relevant videos and PowerPoint slides were sent to the students. Home assignments were done through the online classroom. The students were then made to answer a questionnaire on their perceptions of FC consisting of 5-point Likert items. In addition, a focus group discussion (FGD) was carried out with voluntary participation (n = 13) for an in-depth discussion of flipped teaching. The quantitative data were analysed using the independent t-test, and Atlas.ti was used to analyse the qualitative data. For most of the Likert statements, there was no significant difference (p > 0.05) between the mean results obtained by the male and female students. For example, for the item “The learning material was available before class time”, both the male (mean [SD] = 1.857 [0.443]) and female (mean [SD] = 1.966 [0.365]) respondents confirmed the learning material’s availability before class time (p = 0.121). However, the mean result obtained by the male respondents for the variable “I understood the topics in lesser time compared to the traditional lecture method” was higher than the mean result obtained by the female participants by 0.236, which was statistically significant (95% CI [0.373, –0.100], p = 0.001). Modified FC teaching for the “learning skills” course is thus an effective teaching method. The male students took significantly lesser time understanding the three included topics compared to the female students.
Stress Factors and Depression Levels of International Medical Students in Bulgaria
and Turkish Medical Students
Authors: Vatansever Merve , Georgieva Elia , Velkova Angelika
Published: October 2021

Throughout medical education, medical students are reported to experience high levels of stress and depression. The aim of this study was to compare the stress factors and depression levels of medical students in Bulgaria and Turkey. This cross-sectional comparative study included 546 students (276 international students from abroad studying at the Medical University of Sofia in Bulgaria and 270 Turkish medical students). The questionnaire consisted of sociodemographic questions, a Medical Student Stressor Questionnaire (MSSQ-40 items), and a Beck Depression Inventory (BDI). The Turkish pre-clinical and clinical students had higher levels of stress and depression than the international pre-clinical medical students in Bulgaria. When the medical students were compared, 51.4% of the international medical students in Bulgaria and 28.5% of the Turkish medical students were found to be without depression. Moreover, 26.7% of the Turkish medical students and 12% of the international medical students in Bulgaria had moderate levels of depression. In addition, each domain of the MSSQ had a relationship with depression in both groups of medical students, with the exception of one domain (intrapersonal and interpersonal related stressors), which had no significant relationship with the depression scores of the Turkish clinical students. The findings of our study imply that medical students may need psychological support throughout their education, and this applies especially to Turkish medical students. Knowing the stress factors and depression levels that medical students experience plays an important role in determining the approaches to adopt to them.
SWOT Analysis of the Universiti Sains Malaysia Medical Educationists’ Preparations to Make a Regional Medical Education Hub: A Qualitative Study
Authors: Mat Nor Mohd Zarawi , Yusoff Muhamad Saiful Bahri
Published: October 2021

The aim of this study was to analyse the strengths, weaknesses, opportunities and threats that describe the current circumstances of medical educationists in the School of Medical Sciences in Universiti Sains Malaysia (USM), particularly towards preparing themselves for becoming a regional hub in medical education. A total of 21 documents, including nine strategic management records, three department meeting documents and nine researchers’ observation journals were engaged in this study. The gained data were clustered by themes for each of the four categories which were strengths, weaknesses, opportunities and threats regarding medical educationists in the USM. High motivation and interest of the lecturers, interest in writing, presence of medical background, experienced in clinicals, experienced in management, presence of good health status, presence of postgraduate medical education and the presence of international students were designated as strengths of medical educationists. Presence of personal challenges, a majority of young lecturers and a majority with no PhD were stated as weaknesses of medical educationists. Positive support from family, strong support from the top administration to the medical education department, positive attention to individual instructors, two instructors having a PhD, supportive cadre, positive international perception to the department of medical education and large opportunities for research and school-provided grants were indicated as opportunities for medical educationists. Financial issues and facilities were expressed as threats to medical educationists. Consistent with the positive mode to move forward, there is a good chance for the USM medical faculty to become a medical education hub.
'Wither' the Sharing City?
Authors: Chan Jeffrey K.H. , Zhang Ye
Published: October 2021

The sharing city is a normative framework for sharing resources collaboratively, fairly, and sustainably. Because many sharing practices require some face-to-face interactions, the Covid-19 pandemic has impacted these practices in unprecedented ways. This article aims to assess how
Covid-19 has impacted sharing activities and practices and discusses these impacts focusing on four key points: (i) the enduring alternative of sharing in the commons; (ii) the uneven adaption of sharing practices; (iii) the rise of digital surveillance; and (iv) the civic delight of sharing.
The article concludes with a reaffirmation that despite the challenges presented by the pandemic on the sharing city project, there is no better time than the present to accelerate the momentum of rediscovering and redefining sharing systems in cities. In short – the Sharing City will
not wither.
A Mighty Inconvenience: How Covid-19 Tested a Nation's Continence
Authors: Bichard Jo-Anne , Ramster Gail
Published: October 2021

This paper reviews and reflects on how the Covid-19 pandemic and subsequent lockdowns became a unique period in the United Kingdom's life and the management of its continence when away from home. The lack of forethought and planning for public toilet provision would make local and national
headlines during both lockdown and lockdown easing and remind people how essential such a service is to aff ording movement and participation in our built environment. This work charts the public perception of public toilet provision and its decline both before and during to the pandemic.
It discusses how the shift of a majority of provision into the private sector resulted in reliance on a once public service that would fail in general lockdown, provoking debate on public toilet provision and its essential role in our built environments.
The market value of equity of manufacturing companies during the COVID-19 pandemic
Authors: Savitri Enni , Ary Gumanti Tatang , Syahza Almasdi , Herda Nik Abdullah Nik
Published: October 2021

The market value of a public company reflects the expectations of investors. It is influenced by many factors, both internal and external to the company. This study aims to analyze whether intellectual capital moderates the effect of the debt-to-equity ratio and earnings per share on the market value of equity. A set of historical data was collected and analyzed based on a sample of 114 manufacturing companies listed on the Indonesia Stock Exchange from 2017 to 2019. This study uses moderated regression analysis to test proposed hypotheses and a robustness test to examine the sensitivity and consistency of the study results. The findings show that the debt to equity ratio affects the market value of equity, whilst earnings per share does not affect the market value of equity. The analysis also shows that intellectual capital could strengthen the effect of the debt to equity ratio on the market value of equity. In contrast, intellectual capital could not strengthen the effect of earnings per share on the market value of equity.
AcknowledgmentsThe study was conducted with the support of the Universitas Riau, Indonesia.
Improving Employee Engagement of Muhammadiyah Teachers with Organizational Trust, Distributive Justice, and Psychological Empowerment
Authors: Fadhilaini Cut Rifatmi , Tjahjono Heru Kurnianto , Susanto Susanto
Published: October 2021

The research aimed to look at the factors that significantly influence the teacher’s engagement, especially the factors of organizational trust and distributive justice. In addition, the research was to see the moderating effect of psychological empowerment in the influence of organizational trust on employee involvement and between distributive justice on employee engagement using the hierarchical regression analysis method. The research implemented simple random sampling technique and obtained 150 respondents, who were teachers at Muhammadiyah schools spread across five schools in Kotagede District, Yogyakarta, Indonesia. The results show that organizational trust has a significant effect on employee engagement, while distributive justice does not significantly affect employee engagement. In addition to these factors, psychological empowerment is shown to have a quasi-moderating effect in the effect of organizational trust on employee engagement. Since the analysis is limited to only five Muhammadiyah schools in Kotagede, Yogyakarta, the results cannot generalized. In addition, the COVID-19 pandemic only makes the questionnaires possible via online. Since younger teachers start to dominate, future research is suggested to have a further analysis on different generations (X, Y and Z).
Relationship Analysis of Destination Image, Sports Involvement, Event Quality and Travel Motives as an Antecedent Factors on Revisit Intention in Recurring Running Sports-Event
Authors: Wicaksono Muhammad Angga , Setyaningtyas Tara , Kirana Annesa Nariswari
Published: October 2021

The research aimed to examine the relationship between destination image, sports involvement, quality of sport events, and travel motives as antecedent factors to predict repeat visit intentions of marathon events. This was a further study of the trends that occur in society regarding the changing perception that sport is not only for health purposes, but also as a profitable tourism subject. Data was collected using quantitative, non-probability, purposive sampling methods. The research instrument was an online questionnaire which was distributed to tourists and athletes who took part in running sport-events. The data analysis method uses Structural Equation Modelling with Smart PLS 3.0. The test results show that not all research hypotheses are accepted. Sport-event quality (SQ) has a positive relationship but has no significant effect on revisit intention (RI) from repeated sporting events. The positive effect of travel motive (TM) on the intention to revisit a repetitive sporting event (RI) is proven. Travel motive (TM) also has a positive and significant effect on destination image (DI). Sports involvement (SI) has a positive and significant effect on revisit intention (RI). The same positive and significant effect is also shown in the relationship between sports event quality (SQ) and destination image (DI) variables. Revisit intention (RI) of repeated sporting events was found to be positively influenced by destination image (DI). There is a significant indirect effect of sport-event quality on intention to revisit repeated sporting events (RI), mediated by destination image.
PSYCHODRAMA – THE METHOD WHICH PRODUCE CHANGE IN THE QUALITY OF LIFE OF PSYCHOTIC PATIENTS
Authors:   Faculty of Political Sciences, University of Belgrade, Republic of Serbia, Veljkovic Jasna , Davidovic Dragomir ,   Clinic for psychiatric diseases ‘’Dr Laza Lazarevic’’, Belgrade, Republic of Serbia, Leposavic Ivana ,   University Clinic for Psychiatry, Belgrade School of Medicine, Republic of Serbia, Davidovic Maja ,   Clinic for psychiatric diseases ‘’Dr Laza Lazarevic’’, Belgrade, Republic of Serbia
Published: October 2021

The aim of this a quasi-experimental study is to test the changes in the Quality of Life of chronic mental disorders (schizophrenia) treated with psychodrama. Total sample consisted of 60 subjects, aged 21-38. From these, 30 subjects were in the experimental group, while 30 subjects were in the control group. All subjects were previously psychologically tested, as well as basic demographic data has been taken. The instrument we used was Life Quality Scale in Schizophrenia (21 items form). Qualitative and quantitative analysis of the obtained data indicates a statistically significant improvement of social and communicative abilities of participants of experimental groups, better impulse control and activation in the work area. The disadvantage of this research is: the small sample. Future examination is needed, as well as a more advanced data processing methodology.
CORRELATION BETWEEN PURE TONE THRESHOLDS AND SPEECH THRESHOLDS
Authors:   City General Hospital “8th September”, Department of Otorhinolaryngology, Division of Audiology, Skopje, North Macedonia, Ristovska Lidija , Jachova Zora ,   Ss. Cyril and Methodius University in Skopje, Faculty of Philosophy, Institute of Special Education and Rehabilitation, Skopje, North Macedonia, Kovacevic Jasmina ,   University of Belgrade, Faculty of Special Education and Rehabilitation, Belgrade, Serbia, Radovanovic Vesna ,   University of Belgrade, Faculty of Special Education and Rehabilitation, Belgrade, Serbia, Hasanbegovic Husnija ,   Institute for Human Rehabilitation, Tuzla, Bosnia and Herzegovina
Published: October 2021

Speech detection threshold (SDT) depends on audibility alone, whereas speech recognition threshold (SRT) requires the stimuli to be heard and identified. The aim of the study was to determine the difference between SDT and SRT, and to analyze the correlation between pure tone thresholds and speech thresholds. Difference between SDT and SRT was ≤ 12 dB in majority of cases (p = .018). SDT was strongly correlated with the best pure tone threshold. Pearson correlation coefficient was the highest in “Inverted U” shape (r = .99). There was strong correlation between SRT and PTA (500-2000), PTA (500-4000), and PTA (500-1000), especially in Rising configuration (r = .997, r = .992 r = .989, respectively), as well as, between SRT and frequency of 1000 Hz (r = .989). SRT is in the highest correlation with PTA (500, 1000, 2000 Hz) and with the hearing threshold at frequency of 1000 Hz.
SOCIOLOGICAL METHODS OF RESEARCH OF JUVENILE DELINQUENCY
Authors: Vodnik Valentyna Davidyvna , Klimova Galina Pavlovna , Pidkurkova Iryna Valeriivna
Published: October 2021

This paper discusses some General issues of organizing and conducting an empirical study of juvenile delinquency. Special attention is paid to the methodology of research of the problem related to the personality and career of a minor criminal. In particular, the authors consider the peculiarities of using sociological methods to find out the personal qualities of juvenile offenders and the reasons that led to their committing offenses and crimes.
THE PHENOMENON OF NETWORK WARS: TO THE PROBLEM OF THE PHILOSOPHICAL THINKING
Authors: Danilyan Oleg Gennadievich , Dzoban Оlexander Petrovich
Published: October 2021

The article substantiates that the modern social system, the dynamism and specificity of which are due to the intensive development of information technology and network communications, has dramatically changed the nature of conflict resolution and warfare. It is shown that, in essence, network warfare is reduced to a special form of conflict, when their participants use network forms of organization, doctrine, strategy and technology that are best adapted to the current stage of development of the information society. It turns out that one of the goals of the impact of network wars on society is the destruction of the meaning unity of the world and man, in connection with which the basic values ​​of the people and the state, national, religious and cultural identity are destroyed. The dialectical interrelation of network wars with information and information-psychological wars is shown.
SELF-EDUCATION AS CONDITION OF SOCIAL INDEPENDENCE AND INDEPENDENCE OF PERSONALITY
Authors: Burluka Elena Viktorovna
Published: October 2021

It is investigational as in a modern cultural situation a self-education gives an opportunity to social independence and independence of personality. It is marked that the modern system of education is oriented to activity of personality, on independence in the choice of subjects and time of mastering of information. It is shown as a democratic type of organization of self-education deprives personality of dependence and allows to go out her on the new level of spiritual freedom in realization of creative potential.
Building vibration monitoring based on digital optical cameras
Authors: Wang Wei , Shao Yu
Published: October 2021

The complex and process-critical conditions of machineries are needed to be continuously monitored in order for incipient breakdown to detect and ensure its high performance and operating safety. The change in the resonant frequency is focused by the spectrum analysis which is caused by the structural degradation and for health monitoring, useful information is produced. A test signal is required by the spectral analysis for health monitoring of structural condition. A test signal is the easiest way for structural spectral characteristics measurement but during every measurement, a structure vibration is impractical. Several techniques are presented for the condition of a machine depending on the application monitoring. The structure health would be able to be monitored if structural vibrations are utilized for spectral characteristics measurement due to wind and ground motion. The vision-based monitoring with the sources of errors are detailed and presented in this paper. Different parameters are observed for the different signals, unify the scale and can also be used to signals errors as compared with different levels of amplitudes. The PSNR and Structural Similarity are analyzed, the PSNR value is obtained in the range of 40 dB to 50 dB and the SSIM values are nearby to the 1 for all the signals. The MAPE and MAE values obtained by the presented technique are less for all the signal samples. The presented method outperforms the existed technique by 3.21 % to 44.02 % in form of MAPE. The presented method is 3.21 % to 44.02 % better than the previously existed technique in form of MAPE. The percentage improvement of the presented method outperforms by 33.93 % and 42.43 % in terms of MAE.
Un enclave singular del Neolítico antiguo en el Prepirineo de Lleida: la Cova del Tabac (Camarasa, Lleida)
Authors: Vega Bolivar Susana , Laborda Lorente Rafael , Lanau Hernáez Paloma , Roda Gilabert Xavier , González Marcén Paloma , Mora Torcal Rafael , Martínez-Moreno Jorge
Published: October 2021

La Cova del Tabac representa un hito en la Arqueología de la Península Ibérica al combinar la conservación de registro arqueológico y pinturas esquemáticas. No obstante, ha permanecido largo tiempo en el olvido sufriendo múltiples agresiones que dificultan evaluar su significado. Recientes investigaciones han identificado varias fosas amortizadas con artefactos, destacando un conjunto de cerámicas con decoración inciso-impresa adscritas al Neolítico antiguo. La revisión de las figuras del panel al que se añaden nuevas grafías y el hallazgo de cantos con restos de ocre, incrementan el interés de este enclave. La posición cronométrica del registro material, 5300-5000 cal BC, visibiliza un nuevo evento Neolítico que se rastrea por el Prepirineo Oriental compatible con el rango temporal de las pinturas esquemáticas. Cova del Tabac permite evaluar la irrupción de este fenómeno en los Aspres de la Noguera a finales del VI Milenio BC.
Motivation for citizen e-participation in urban development: The case of “Our St. Petersburg” portal
Authors:   EMEIA, Apple GmbH, Aubakirova Karina I. , Golubeva Anastasia A. ,   St. Petersburg State University, Sokolova Ekaterina V. ,   St. Petersburg State University
Published: October 2021

The article gives an overview of the literature on electronic participation in the urban development, the analysis of the main characteristics and principles of the portal “Our St. Petersburg” as one of the main platforms for electronic participation of the citizens. The purpose of this study is to develop recommendations for increasing the level of electronic participation of citizens in the urban development of St. Petersburg. Based on the data collected during the focus groups interviews as well as the survey of the portal users and those who do not use it, the main drivers and barriers to e-participation in urban development were identified, and the recommendations for increasing public participation were proposed. The cluster analysis made it possible to identify several groups of St. Petersburg residents with similar drivers and barriers to e-participation and formulate recommendations for improving e-participation of citizens on the basis of management of the Portal individual characteristics.
Evolución del comercio electrónico: una perspectiva desde China y América Latina
Authors: Paipa Bolaños Camila Andrea
Published: October 2021

El presente artículo analiza los efectos que ha tenido la apertura del comercio electrónico transfronterizo o e-commerce (electronic commerce) y las nuevas formas de generar relaciones comerciales internacionales tomando en cuenta el modelo económico de China, basado en exportaciones, el cual ha influido en el desarrollo de las economías emergentes de Latinoamérica, entre ellas, Brasil, México, Argentina, Colombia, Perú y Chile, lo que convierte a la región en una de las de mayor crecimiento en la nueva economía digital, gracias al flujo de mercados que, a su vez, permite generar nuevas estrategias de desarrollo tanto para el gigante asiático como para los países suramericanos mencionados.
La lucha contra el crimen organizado transnacional en Brasil y Chile
Authors: Gómez Sánchez Manuela , Malagón Siachoque Brandon Felipe , Quintero Cordero Sara Patricia
Published: October 2021

El presente trabajo busca analizar tanto las políticas de seguridad como las líneas de acción estratégica de Brasil y Chile sobre la lucha contra el crimen organizado transnacional (COT), teniendo en cuenta los diferentes factores que influyen en la expansión de este en esos Estados. Para tal efecto, es necesario identificar las diferentes organizaciones delincuenciales que afectan de manera exponencial la seguridad y defensa nacionales de Brasil y Chile, de igual forma, identificar cuáles son los principales factores que han permitido el surgimiento de estos grupos organizados, de qué forma afectan la seguridad y defensa de los países estudiados y cuáles son las estrategias que ha implementado el Estado colombiano para combatir el COT en Colombia. Con base en tales presupuestos, surge la pregunta acerca de cuáles han sido las estrategias de seguridad nacional implementadas por Brasil, Colombia y Chile, entre los años 2010 y 2018, que han impedido un avance de la amenaza del COT.
Спектральное исследование фотодинамических процессов в системе C-=SUB=-60-=/SUB=--(н-метилпирролидон)-кислород
Authors: Кисляков И.М. , Белоусова И.М. , Киселев В.М. , Багров И.В. , Стародубцев А.М. , Zhang Tianju , Wang Jun
Published: October 2021

The processes of photoexcitation and energy transfer in an air-saturated solution of fullerene C60 in n-methylpyrrolidone are studied. With femtosecond laser pumping at a wavelength л(p) = 520 nm, transient absorption spectra were obtained in the range 470-750 nm. Broadband absorption is observed at л > 650 nm as a result of aggregation of fullerene molecules, characterized by a short decay time of the picosecond scale. The analysis of the time dependencies indicates the presence of several processes. Within the proposed interpretation, we state a remarkable reduction in the time of singlet-triplet intersystem crossing with an increase of nanocluster size while the rapid quenching of the singlet state varies only slightly. The quantum yield of the triplet state can therefore increase, reaching 0.14. The phosphorescence spectra of singlet oxygen with a maximum at л = 1276 nm were measured with LED excitation at various wavelengths in the range 370-625 nm. The lifetime and quenching rate constant of singlet oxygen in n-methylpyrrolidone are determined. The combined quantum yield of triplet fullerene and singlet oxygen in n-methylpyrrolidone is estimated as 0.74. The efficiency spectra of the singlet oxygen photosensibilization in the C60-(n-methylpyrrolidone)-oxygen system are obtained, indicating the increasing role of large nanoclusters in this process during aging of the solution.
Генерация второй гармоники-суммарной частоты в тонком сферическом слое. IV. Оптимизационный анализ
Authors: Толкачёв А.И. , Шамына А.А. , Капшай В.Н.
Published: October 2021

A numerical maximization of the intensity of the generated radiation of second harmonic–sum frequency from a thin spherical layer is carried out. It is found that, for all the considered anisotropy types and any size of the spherical layer, the maximum of the intensity is observed at the same parameters of the problem, and an increase in the particle size leads to an increase in generated spatial power density. It is shown that, for large particle sizes, the intensity of the generated radiation is proportional to the fourth power of the particle radius. The distribution law of the generated power density is found analytically for one of the anisotropy types in the case of codirectional incidence of waves on a spherical particle of small radius.
Антистоксова люминесценция в углеродных материалах
Authors: Рехвиашвили С.Ш. , Гаев Д.С. , Маргушев Ч.
Published: October 2021

The IR laser-induced radiation of carbon materials is experimentally investigated. The broadband spectra of radiation in the visible region, as well as the redshift of the spectra of dispersed carbon materials relative to the spectra of bulk polycrystalline graphite, have been found. All measured spectra are typical for incoherent dipole radiation. Broadband radiation is qualitatively explained by Raman scattering of photons.
Googling for Suicide–Content and Quality Analysis of Suicide-Related Websites: Thematic Analysis
Authors: Chen Wen , Boggero Andrea , Del Puente Giovanni , Olcese Martina , Prestia Davide , Jahrami Haitham , Chalghaf Nasr , Guelmami Noomen , Azaiez Fairouz , Bragazzi Nicola Luigi
Published: October 2021

Background

Suicide represents a public health concern, imposing a dramatic burden. Prosuicide websites are “virtual pathways” facilitating a rise in suicidal behaviors, especially among socially isolated, susceptible individuals.

Objective

The aim of this study is to characterize suicide-related webpages in the Italian language.

Methods

The first 5 most commonly used search engines in Italy (ie, Bing, Virgilio, Yahoo, Google, and Libero) were mined using the term “suicidio” (Italian for suicide). For each search, the first 100 webpages were considered. Websites resulting from each search were collected and duplicates deleted so that unique webpages could be analyzed and rated with the HONcode instrument

Results

A total of 65 webpages were included: 12.5% (8/64) were antisuicide and 6.3% (4/64) explicitly prosuicide. The majority of the included websites had a mixed or neutral attitude toward suicide (52/64, 81.2%) and had informative content and purpose (39/64, 60.9%). Most webpages targeted adolescents as an age group (38/64, 59.4%), contained a reference to other psychiatric disorders or comorbidities (42/64, 65.6%), included medical/professional supervision or guidance (45/64, 70.3%), lacked figures or pictures related to suicide (41/64, 64.1%), and did not contain any access restraint (62/64, 96.9%). The major shortcoming to this study is the small sample size of webpages analyzed and the search limited to the keyword “suicide.”

Conclusions

Specialized mental health professionals should try to improve their presence online by providing high-quality material.