bluuebunny/crossref_metadata_2025 huggingface dataset:
Multidimensional Internet Use, Social Participation, and Depression Among Middle-Aged and Elderly Chinese Individuals: Nationwide Cross-Sectional Study (Preprint)
Authors: Du Xiwang , Liao Jiazhi , Ye Qing , Wu Hong
Published: November 2022

BACKGROUND

There is growing evidence that the internet has beneficial effects on the mental health of middle-aged and older people (≥45 years), but the evidence is inconclusive, and the underlying mechanisms are less known.

OBJECTIVE

This study aims to explore the relationship between multidimensional (devices, frequency, and purpose) internet use and depression in middle-aged and elderly Chinese, as well as the mediating effect of social participation. Moreover, this study will explore the moderating effect of the regional informatization development level (RIDL) on the relationships between individual internet use, social participation, and depression.

METHODS

Data on 17,676 participants aged 45 years or older were obtained from the China Health and Retirement Longitudinal Study (CHARLS) 2018 data set. The 10-item Center for Epidemiologic Studies Depression Scale (CES-D-10) was used to identify the presence of depression. Logistic regression was used to explore the relationship between each dimension of internet use and depression. Multiple linear regression was used to explore the mediating effect of social participation and the moderating effect of the RIDL.

RESULTS

The results showed that 28.33% (5008/17,676) of the total population had depression. In terms of regional subgroups, respondents living in the western region exhibited the highest proportion of depression (2041/5884, 34.69%). Internet use was negatively associated with depression (odds ratio 0.613, 95% CI 0.542-0.692; P<.001). Various dimensions of internet use positively contributed to individual social participation and reduced individual depression (devices: β=–.170, 95% CI –0.209 to –0.127; frequency: β=–.065, 95% CI –0.081 to –0.047; and purpose: β=–.043, 95% CI –0.053 to –0.031). In addition, the RIDL weakened the relationship between individual-level internet use and social participation (internet use: F74.12,9.82=7.55, P<.001; devices: F51.65/9.88=5.23, P=.005; frequency: F66.74/10.08=6.62, P=.001; and purpose: F66.52/9.78=6.80, P=.001), and negatively moderated the relationship between the frequency of internet use and depression (frequency: F662.67/188.79=3.51, P=.03).

CONCLUSIONS

This study found that different dimensions of internet use are associated with lower levels of depression. Social participation partially mediates the association between multidimensional internet use and depression in the eastern, central, and western regions, respectively. Additionally, the RIDL helps individuals further their internet use and social participation, reducing the impact of depression. However, this effect weakens sequentially from the western region to the central region and then to the eastern region.
Liver Enzymes and Blood Lactate Profile of Patients Diagnosed with Typhoid Fever in Abuja, Nigeria. (Preprint)
Authors: Anunobi Oluchukwu Ogechukwu , Ojo Rita Ewela
Published: November 2022

BACKGROUND

Typhoid fever resistance is on the increase and this frustrates efforts at treatment. Persistence of multiple drug-resistant (MDR) typhoid fever leads to higher mortality rate since treatment is evasive.

OBJECTIVE

This study intended to identify if liver enzymes and lactate levels are related to aggravating MDR in patients diagnosed with typhoid fever.

METHODS

50 subjects were recruited, 45 were positive for Widal test and further subjected to stool culture examination for the presence of S. Typhi. All subjects blood were analysed for lactate, alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP)

RESULTS

Growth of S. Typhi was observed in only eight subjects out of the 45 Widal positive test subjects. The eight positive S. Typhi isolates showed resistance to the first line drugs, macrolides and 3rd generation cephalosporins but showed susceptibility to fluoroquinolones. ALP, AST, ALT and blood lactate were elevated in all multi-drug resistant patients. Highest levels of liver enzymes were observed in subjects resistant to the greatest number of antibiotics. However, there was no significant correlation of increase in blood lactate level and ALP when compared with increase in resistance based on number of antibiotics (R2=0.2858, R2=0.4675).

CONCLUSIONS

Lactate and liver enzyme levels increase markedly during typhoid fever infection, however in MDR scenario, especially in resistance to different classes of antibiotics, the metabolic toll on the liver increases and is reflected in elevation of AST and ALT. Keywords: Antibiotics, liver enzymes, lactate, typhoid fever, multiple drug resistance
Evaluating the Acceptability and Appropriateness of the Augmented Reality Home Assessment Tool (ARHAT) (Preprint)
Authors: Fitzpatrick McKenzie , Kinney Lauryn , Lee Jenny , Sprecher Bryce , Tredinnick Ross , Ponto Kevin , Shin Jung-hye , Fields Beth
Published: November 2022

BACKGROUND

The Augmented Reality Home Assessment Tool (ARHAT) is one example of a mobile-based application. The ARHAT was developed to provide rapid, highly accurate assessments of the home environment by utilizing 3D capture technologies that helps people identify and address functional limitations and environmental barriers.

OBJECTIVE

This study was conducted to gain stakeholder feedback on the acceptability and appropriateness of the ARHAT for identifying and addressing barriers within home environments.

METHODS

A qualitative descriptive study was conducted because it allows for variability when obtaining data and seeks to understand stakeholders’ insights on an understudied phenomenon. Each stakeholder group (occupational therapists, housing professionals, and aging adults and their caregivers ‘dyads’) participated in a 60-minute, virtual focus group via a secure Zoom platform. Focus group data were thematically analyzed by two trained qualitative research team members that followed four steps:1) reading transcribed interviews, 2) generating codes for data, 3) condensing codes into themes, and 4) naming and defining key themes.

RESULTS

A total of 19 stakeholders, ages 18-85+, were included in the study. Of the occupational therapists (26%), housing professionals (16%), and dyads (58%), 32% were male, and 68% were female, with most living in the Midwest (53%). Four main themes emerged from the focus group data and demonstrate the acceptability and appropriateness of the ARHAT: workflow, style, measurement tools, and impact. All stakeholders stated that they could see the ARHAT being used at many different levels and by any population. Dyads specifically mentioned that the ARHAT would allow them to do forward planning and made them think of home modifications in a new light.

CONCLUSIONS

The ARHAT is acceptable and appropriate for identifying and addressing functional limitations and barriers in the home environment. This study highlights the importance of considering the workflow, style, measurement tools, and potential impact of home assessment technology early in the developmental process.

CLINICALTRIAL

Not applicable.
Звернення головного редактора
Authors: Shekera O.G.
Published: November 2022

No abstract
Короткий екскурс – Україна
Authors: Authors No
Published: November 2022

No abstract
Медичне забезпечення збройних сил НАТО
Authors: Shekera O.G.
Published: November 2022

Співробітництво з НАТО у військовій сфері розглядається як важливий елемент партнерства України з цією організацією, в цілому. Забезпечення якісною медичною допомогою військовослужбовців у Збройних силах України та інших структурах сектора безпеки держави в контексті євроатлантичної інтеграції є пріоритетним напрямком стратегічного планування політики охорони здоров’я. Мета. Визначити особливості розвитку медичного забезпечення Збройних сил НАТО, спрямованого на збереження і зміцнення здоров’я військовослужбовців та вплив на формування медичного забезпечення Збройних сил України. Результати. У даний час стоїть завдання докорінного реформування військової охорони здоров’я, метою якого є створення системи, яка б відповідала новим соціально-економічним умовам і сучасним завданням навчально-бойової підготовки військ. Реформа торкається управління, планування, фінансування, кадрової політики, оцінки кваліфікації, соціального захисту військових лікарів, середніх медичних працівників і хворих, матеріально-побутового і соціально-психологічного забезпечення. Вона передбачає перехід від відомчої до територіальної організації медичного забезпечення на рівні військових гарнізонів і визначених зон територіальної відповідальності, інтеграцію військово-медичної служби із загальнодержавною системою охорони здоров’я, створення економічного механізму підвищення якості медичної допомоги. Регламентуючим документом з питань збереження життя і здоров’я медичного складу, який служить інструкцією для командирів, медичних начальників усіх рангів та військово-медичного персоналу, є військово-медична доктрина. Висновки. Новизна даної інформації зумовлюється висвітленням реальних шляхів підвищення ефективності функціонування медичних служб Збройних сил України та інших структур сектора безпеки держави.
Воєнно-медична доктрина України
Authors: Authors No
Published: November 2022

No abstract
Вплив сучасних видів зброї на величину і структуру санітарних втрат (презентація)
Authors: Shekera O.G.
Published: November 2022

No abstract
Міжнародне право. Кодекс поведінки медичного персоналу, що бере участь у збройних конфліктах (презентація)
Authors: Shekera O.G.
Published: November 2022

No abstract
Види та обсяг медичної допомоги у воєнний час (презентація)
Authors: Shekera O.G.
Published: November 2022

No abstract
Медичне сортування. Організація та принципи медичного сортування поранених і хворих (презентація)
Authors: Shekera O.G.
Published: November 2022

No abstract
Особливості організації сучасної системи лікувально-евакуаційного забезпечення військ (презентація)
Authors: Shekera O.G.
Published: November 2022

No abstract
BER Performance Improvement of Dual Chaotic Maps Based on STBC Communication System
Authors: Abdulameer Lwaa Faisal , Sripati U. , Kulkarni Muralidhar
Published: December 2022

Sensitive information of any multimedia must be encrypted before transmission. The dual chaotic algorithm is a good option to encrypt sensitive information by using different parameters and different initial conditions for two chaotic maps. A dual chaotic framework creates a complex chaotic trajectory to prevent the illegal use of information from eavesdroppers. Limited precisions of a single chaotic map cause a degradation in the dynamical behavior of the communication system. To overcome this degradation issue in, a novel form of dual chaos map algorithm is analyzed. To maintain the stability of the dynamical system, the Lyapunov Exponent (LE) is determined for the single and dual maps. In this paper, the LE of the single and dual maps have been computed numerically. Increasing the dynamical behavior of the system by using more complex chaotic maps leads to inferiority in the overall system performance. So, in this work, the BER performance for the dual and single chaotic maps by exploiting the benefits of a hybrid Chaos Shift Keying-Multiple-Input-Multiple-Output (CSK-MIMO) communication system has been investigated. The results show that the dual tent map has more randomness, whereas the single logistic map has the least randomness. As well as the CSK-MIMO gives an outstanding BER performance when it compared with the SISO system which helps in reducing the system’s inferiority.
Exploring the Effect of DNA Noise and Current on the Berry Phase Effects
Authors: Roy Subhamoy Singha
Published: November 2022

We have studied here that bend and twist are not two separate entities but one depends on the other, also other hand entanglement of two DNA molecule inserting spin-echo to one of them marks the transform of Berry phase that can be exact as a calculate of entanglement. This formalism helps us to depict the thermodynamic entropy as entanglement entropy and the entanglement of spin can be used as a resource for genetic in order. This implies that the transcription of genetic in order can be considered in the structure of quantum in sequence hypothesis.
“Truth and Mystery”: Pearl S. Buck’s The Good Earth and the Research on Overseas Establishment of Chinese Image
Authors: Zhou Peishen , Cui Dan
Published: November 2022

This paper aims to analyze the issue if Pearl S. Buck conveys an authentic image of China in The Good Earth by composing typical and important aspects ranging from the life of Chinese lower class to the their spiritual status through realistic style. This article reflects its mysterious characteristics by analyzing Buck’s writing of Chinese exoticism and spiritual simplicity and plainness in the novel. Meanwhile, through the exploration of the harsh social conditions, the physical and mental suffering of social oppression, and the tragic fate under the feudal foolishness, Peal tries to find out the true side of China. In addition, through further study, it is found out that Pearl’s portraying of China is featured with waving position: a sense of fusion of and contradiction between mystery and authenticity, thus presenting a contradictory and compatible image of China.
Effect of Foreign Direct Investment on Economic Growth in Nigeria: Does Exchange Rate Matter?
Authors: Bashir Danladi
Published: November 2022

This study investigates the effect of foreign direct investment on economic growth in Nigeria for the period from 1986 to 2020; a particular attention is also given on the role of exchange rate in the relationship between foreign direct investment and economic growth using annual time series data sourced from the database of World Development Indicator (WDI) of the World Bank and Central Bank of Nigeria (CBN) 2021 Statistical Bulletin. Autoregressive Distributed Lag (ARDL) model was employed for the analysis. The study found that FDI has positive and significant effect on economic growth. Exchange rate also has a positive and significant effect on the economic growth. Findings also show that the regression is significant at 5% level of significance as F-statistic is less than 0.05. This entails that the growth effect of FDI is enhanced in the presence of a stable exchange rate. Based on the findings, the study suggests an improvement in the institutional quality so as to attract the further inflow of foreign direct investment in Nigeria. The study also suggests that government should make exchange rate stable so that more foreign investment can be attracted for desired economic growth and development in the country.
Analysis on the Interactive Embodiment of the East and West Values of Life in Chinese and American Movies
Authors: Wei Zhongtang
Published: November 2022

The discussion of the contents and differences and interrelations of east and west values has been keeping on for a long time and has made much progress. But few studies have done on the interactive embodiment of the east and west values. The paper illustrated, under the background of economic globalization and cultural communication; firstly, the traditional embodiment of east values in Chinese movies and west values in American movies; secondly and more specifically, the interactive embodiment of the east and west values of life in Chinese and American movies. Through the lens of movies, we can behold the inner secrets of different values, which are demonstrated in distinct perspectives like the subtle and implicit plots. It is expected that, when we compare the values in two countries and cultures, we will be more aware of our own cultures. We could be capable to grasp in our cultures what we are good at and what we should be better, which further would help us enhance the confidence of our own cultures and values and learn from others better to refine and improve the development of our traditional cultures and then to spread it more and better to the whole world.
Street Light Control System
Authors: Mankawade Amruta , Kadam Sanika , Kale Omkar , Kanawade Aditya , Kamble Anish , Kharche Sejal
Published: November 2022

Abstract: Automatic Street light systems require less maintenance than traditional street lights because they do not have any moving parts. Because the autonomous street light system is self-contained, it does not require any external wiring or grid connection. When the sunlight falls below the visible region of our eyes, the lights in this Street Light Control System will automatically turn on, and when the sunshine returns, the lights will immediately turn off.There is no requirement for manual operation in this project, such as setting the ON and OFF times. This system uses a motion detection sensor which helps to automatically increase the intensity of the street light when a car or pedestrian is noticed in the area. If there is no activity in the area, the light is automatically changed to a minimum light level that is optimum.
The Knowledge Regarding Identifying Learning Difficulties of Primary School Children
Authors: Thakur Sruchi , Upadhyay Jay Kumar
Published: November 2022

Abstract: All the health care professionals must take an extensive effort to educate the people to identify the learning difficulties. Researcher felt the need of conducting the research on reduction of learning difficulties among primary school teachers as it is a major modifiable risk factor in the world. A descriptive research approach was used and the research design adopted for the present study was descriptive. The target population for the study was primary school children at selected schools in Urban and Rural Area of Greater Noida, UP. Sample size was 100 ,50 teachers in Rural Area and 50 teachers in Urban Area . The data analysis was done on the basis of objectives and hypothesis of the study. The aim of the study was to assess the knowledge of risk factors on learning difficulties in primary school children.
Case Study: Snakebite Envenomation in Toddler and Acute Abdomen
Authors: Mathew Ms. Blessy , Solanki Ms. Sanju
Published: November 2022

Abstract: The Child aged 10 year was bought to the Emergency Department of Chhatrapati Subharti Hospital with the chief complaints of no body movement which was diagnosed as the case of cardiac arrest as per the evidences suggested by recordings of vital parameters. History taken from the father revealed the toddler boy had a snake bite in middle finger of the left hand. After wards child complained of severe abdominal pain and the entire body got collapsed and they rushed to hospital as a lifesaving attempt, where CPR was initiated in hospital first which was followed by the emergency treatment in the form of administration of Anti snake venom Anti serum and after wards the child was admitted in paediatric ICU and was on the medical treatment for 10 days and on after which the boy was shifted to general ward and 15th day he got discharged.
Detection of Diabetes Using 5G Network
Authors: Sireesha P , Narmada Kongara , Chandana Kadurkapu , Badri Govindu , Shirisha Kalakonda
Published: November 2022

bstract: Recent advances in wireless networking and big data technologies, such as 5G networks, medical big data analytics, and the Internet of Things, along with recent developments in wearable computing and artificial intelligence, are enabling the development and implementation of innovative diabetes monitoring systems and applications. Due to the life-long and systematic harm suffered by diabetes patients, it is critical to design effective methods for diagnosing and treating diabetes. Based on our comprehensive investigation, this article classifies those methods into Diabetes 1.0 and Diabetes 2.0, which exhibit deficiencies in terms of networking and intelligence. Thus, our goal is to design a sustainable, cost-effective, and intelligent diabetes diagnosis solution with personalized treatment. In this article, we first propose the 5G-Smart Diabetes system, which combines state-of-the-art technologies such as wearable 2.0, machine learning, and big data to generate comprehensive sensing and analysis for patients suffering from diabetes. Then we present the data sharing mechanism and personalized data analysis model for 5G-Smart Diabetes. Finally, we build a 5GSmart diabetes testbed that includes smart clothing, a smartphone, and a big data cloud. These experimental results show that our system can effectively provide patients with personalized diagnoses and treatment suggestions.
Analysis of Water Distribution Network Using Epanet for Normal and Leakage Condition and Its Effect on Pressure
Authors: Jawale Priyanka , Kamire Ms. Ankita , Iyer Vignesh
Published: November 2022

Abstract: Water distribution network is a system of engineered hydrologic and hydraulic component which supplies water from the source to the required area. In the design of water distribution network, it is crucial that the network supplies the forecasted demands with enough residual heads at all nodes of the network during the entire design period. However with the increasing change in future scenario, either the nodal demands change or the water distribution network falls short to meet the increasing demands. Therefore, we require a proper analysis of water networks to strengthen them for future. In situations like this, softwares play a major role in analyzing water distribution network to make it work as per the design. The present study is an effort to analyze the water supply network using available software, it proposes hydraulic simulation model for water distribution network analysis and comparison of results.
Pharma Sort
Authors: Mone S. P. , Bafna Jinendra , Nikam Yash , Lokhande Shreyas , Pote Prashant
Published: November 2022

Abstract: Pharma Sort is a Web Application that ensures the Management Process of the Medical distributor is done in a smoother way. The System will also help in decreasing errors mostly caused by Humans. The System provides distributors with various moduleswhich will help them to ease up the process related to debt recovery, handling complaints, and help analyse the product. This System describes the whole details Analytics of Sales using Data Analytical Methods and Algorithms, the project will help the medical distributor form a solid plan for their further marketing strategies. The algorithms used are such that they will give a solid understanding to the user about the company sales and allow them to execute their future sales operation according to the analysis generated.
Decentralization using Blockchain as a Service
Authors: Thorat Madhuri B. , Patil Marmik S.
Published: November 2022

Abstract: Due to its immutability, traceability, anonymity, and transparency as a decentralised distributed ledger, blockchain has seen significant development in cryptocurrencies and production as a new trend. The emergence of Blockchain-as-a-Service (BaaS) in the interim aids in the mitigation of the Blockchain system complexity and management challenges make it simpler for developers to concentrate on implementing business logic. However, the majority of current BaaS solutions are hosted by cloud providers, increasing the risk of vendor lock-in and undermining blockchain's intrinsic trustlessness. Although current BaaS systems use edge computing or the cloud as their infrastructure, their availability is constrained by the availability of network connections and the data centre itself. Most developers or teams find it challenging and expensive to create, maintain, and watch over a blockchain network that supports their apps due to the intricacy of blockchain technology. The majority of regular developers or teams are unable to guarantee the dependability and security of the blockchain system, which in part lowers the calibre of their programmes. The BaaS platform we create in this study,BaaS, offers blockchain services across cloud computing environments, including network deployment and system monitoring, smart contract analysis, and testing. Based on these services, developers don't have to worry about maintaining and monitoring the system and can instead concentrate on the business code to investigate how to apply blockchain technology to their business scenarios more effectively.
A Survey on Automated Assessment Questions Generation System Using Supervised Algorithms
Authors: Rao P. Srinivasa , Kiranmai T. V. V. , Samhitha E. , Shiva R. Sai , Kusuma S.
Published: November 2022

Abstract: The only method for gauging the effectiveness of a teacher's lessons and the learning results of students is examination. Creating the questions and then randomly assigning them to the test are processes in the manual production of test papers. It takes a lot of time and effort to manually create test papers that match the standards of a good test paper. Mainly generating the test papers to evaluate the student technical skills is more time taking and the recruiters always want to know the students in better way by conducting the tests in the technical concepts. Our system helps in generating the questions automatically from the database which consists of the questions of the various technical concepts. To store the data and access the information from the database we are using MYSQL. To generate the test paper with the questions based on the skills known by the candidates we are using the classification algorithm like Naive Bayes Classifier, Random Forest Classifier and the Decision Tree. Naive Bayes, Random forest and Decision tree ,all are supervised algorithms. Giving the questions depending upon the candidate skills in the test paper will effectively evaluate the knowledge of the candidate in the skills that they know rather than testing their knowledge in completely unknown domain, the recruiters will also get the chance to know the candidate capabilities accurately and they can use the skills of the candidates in the better way and they can allocate the work to the candidates based on their performance in the particular skill. To know the performance of the candidate in the test , we have provided the graphical user interface (GUI) which was designed using the HTML and CSS concepts, where the questions are generated depending upon the classified results of the candidates.
PREVALENCE AND FACTORS AFFECTING THE UTILIZATION OF ANTENATAL CARE IN SANA’A CITY, YEMEN
Authors: Al-Shamahy Hassan Abdulwahab
Published: November 2022

Back ground and objective: Antenatal care (ANC) is a health care intervention intended to ensure the safety of pregnancy. According to the World Health Organization, at least four ANC visits are recommended for a healthy pregnancy. However, whether this recommended number of visits was followed or not in the urban or rural areas of Yemen is not known. Therefore, the study aimed to investigate the prevalence of, and the associated factors of ANC utilization by pregnant women in the city of Sana’a, Yemen.
Methods: This study is an Institutional based cross-sectional descriptive study of married pregnant women practices toward ANC services. The sample size was calculated by Epi-Info to be 452 participants; multistage sampling was adopted. Data was collected direct interviews using a structured questionnaire with close-ended questions. Local language questionnaire was used. The questionnaire consists of  several parts (Demographic characteristics, obstetric history, and practices (utilization of ANC) at 10- Health centers of Sana’a City, Republic of Yemen. Epi-Info was used for data analysis, χ2 was calculated and p. value < 0.05 was considered as a cut off for significance of deference.   
Results: The response rate was 99.1%.  Only 214 (47.3%) of the respondents have adequate utilization of ANC. Adequate ANC utilization was high in educated mother, educated husband, high and moderate income, mothers with children >5. According to obstetric factors, adequate ANC utilization was high in mothers whose age at first pregnancy was more than 20 years, primigravida and  primipara.
Conclusion: The study results highlight the need to increase the number of ANC visits, and the importance of using an appropriate model to determine the important socio-demographic factors that ANC service providers shall focus on to improve the health of the unborn baby and the mother during pregnancy.
                       
Peer Review History:
Received: 4 July 2022; Revised: 12 August; Accepted: 7 September, Available online: 15 September 2022
Academic Editor:  Dr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, amaka_mgbahurike@yahoo.com
Received file:                             Reviewer's Comments:
Average Peer review marks at initial stage: 5.5/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Dr. Wadhah Hassan Ali Edrees, Hajja University, Yemen, edress2020@gmail.com
Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, ahsndkyc@gmail.com
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Üçüncü Basamak Bir Hastanede Sağlık Çalışanlarının COVİD-19 Enfeksiyonu ve Aşılaması Hakkındaki Yaklaşım ve Davranışları
Authors: SALMAN Zeliha , SALMAN Hakan , AKÇAM Mustafa
Published: November 2022

Amaç: Pandemide sağlık çalışanlarının COVID-19 hastalığı ve aşısıyla ilgili yaklaşım ve davranışlarını belirlemek. Materyal-Metot: Çalışma, 1-31 Mart 2022 tarihlerinde hastanede görevli sağlık çalışanlarına COVID-19 enfeksiyonu ve aşılarıyla ilgili yaklaşım ve davranışlarını sorgulayan 44 soruluk ankete Whatsapp aplikasyonu üzerinden verdikleri cevaplar toplanarak yapıldı. Bulgular: Çalışmaya katılan 311 sağlık personelinin 209’u kadındı. (%67,2). Ortanca yaşları 36 idi. Katılımcıların 203’ü (%65,3) üniversite mezunu, 159’u (%51,1) hekimdi. Kronik hastalığı olan 51 olgu (%16,4) vardı. Sağlık çalışanlarından COVID-19 enfeksiyonu geçiren 141 (%45,3), ailesinden biri enfeksiyonu geçiren 176 (%56,6), ailesinden biri enfeksiyona bağlı yoğun bakımda kalan 23 (%7,4) ve ailesinden biri enfeksiyona bağlı vefat eden 22 (%7,1) kişiydi. Aşı olan 304 (%97,7) sağlık çalışanından 211’inde (%67,8) en az bir yan etki gelişti. En sık görülen yan etki 156’sında (%73,9) halsizlikti ve en sık yan etki Biontech (%59,8) ile görüldü. Seçenek olsaydı %70,1’i Biontech aşısının ilk tercihleri olacağını belitti. Turkovac aşısına güvenen 131 (%42,1) kişi vardı. Toplum sağlığı açısından aşının zorunlu olması gerektiğini düşünenlerin oranı %83,3, COVID-19 aşısı ile pandeminin biteceğine inananlar %58,8 ve hasta sayısının azalacağına inananlar %80,4 idi. Sağlık çalışanlarında aşıya karşı kararsızlığı arttıran nedenler arasında en sık aşıların yan etkilerine yönelik duyulan endişe (%74) yer alıyordu. Hekim grubunda çocuğuna aşı yaptırma, aşı ile pandeminin biteceği inancı, aşı ile hasta sayısının azalacağı inancı ve yakınlarınıza aşı önerir misiniz sorununa pozitif cevap verenlerin oranı istatistiksel olarak daha yüksektiSonuç: Sağlık çalışanları arasında COVID-19 aşısı olma oranı ve Biontech aşısına olan güven yüksekti. Bunun sebebi COVID-19 aşısı ile pandeminin biteceği veya hasta sayısının azalacağı inancının yüksek olması olabilir.
A Comparison of the Short-Term Efficacy of Physiotherapy Approaches in Patients with Lateral Epicondylitis
Authors: ÇAKIR Şahin , TUNCER Ayşenur , ARPACI Muhammed Furkan , ARGALI DENIZ Mine
Published: November 2022

The study aimed to investigate the short-term effects of radial nerve self-mobilization [RNSM], manual therapy [MT], and extracorporeal shock wave therapy [ESWT] on pain, pain-free grip strength, functional status, and patient satisfaction in patients with Lateral Epicondylitis [LE] and to determine the superiority of these methods to each other. 48 patients diagnosed with LE were included in the study and were randomly divided into three groups. RNSM was applied to all patients as a home program. The first group [n=16] received only the RNSM as a home program, the MT group [n=16] received MT combined with RNSM, and the ESWT group [n=16] received ESWT combined with RNSM. The RNSM was applied five days per week, and the MT and ESWT for two sessions per week for three weeks. Pain severity, pain-free handgrip strength, functionality levels, and patient satisfaction were evaluated before and after three weeks of treatment. The pain level significantly decreased, and handgrip strength and functionality increased in all groups after three weeks [p<0.001]. In comparison between the groups, the decrease in pain level, the increase in maximum grip strength, and patients' overall satisfaction scores were found to be higher in the MT group than in the ESWT, and only the RNSM groups [p<0.05]. MT application combined with radial nerve self-mobilization exercises in the treatment of LE appears to be more effective.
COVID-19 hastalarında dalak boyutu ve hematolojik parametrelerinin klinik önemi
Authors: YÜRÜK ATASOY Pinar , BEYDOĞAN Engin
Published: November 2022

Amaç: Şiddetli akut solunum sendromu koronavirüs 2'nin (SARS-CoV-2) neden olduğu COVID-19, sistemik tutuluma neden olur ve dalak hedef organlardan biri olabilir. Bu çalışmamızda COVID-19 hastalarının hastane başvurusu sırasında çekilen bilgisayarlı tomografi (BT) kesitlerindeki dalak boyutu ve laboratuvar parametrelerinin COVID-19'un sonlanımı üzerine etkisini değerlendirmeyi amaçladık.Materyal-Metot: Bu retrospektif kohort çalışmasına Nisan ve Aralık 2020 tarihleri arasında hastanemize başvuran 644 COVID-19 hastası alındı. Hastaların medikal kayıtları toplandı ve başvuru anında çekilen Toraks BT kesitlerinde dalağın tümünün değerlendirilebildiği Toraks BT’ler gözden geçirildi.Bulgular: Çalışma popülasyonu, medyan yaşı 59 (45 – 69 yıl) olan 644 hastayı (387 erkek, 57 kadın) içermektedir. COVID-19 ile ilişkili en yaygın üç sistemik hastalık hipertansiyon (%28), diabetes mellitus (%22.2) ve kalp hastalığıydı (%18.6). Başvuru sırasında en sık görülen aktif şikayet nefes darlığı (%57,5) ve öksürükdü (%46). 644 hastann 109’u mortal seyretti. Başvuru sırasında, mortalitesi olan hastalarda medyan lökosit sayısı daha yüksek olmasına rağmen (8.9'a karşı 6.5, p<0.001), lenfosit sayısı (1.3'e karşı 1.0, p<0.001) ve trombosit sayısı (200'e karşı 187, p= 0.035) mortalitesi olmayan hastalarda daha yüksekti. Çalışma popülasyonunun 173'ünde (%26,9) splenomegali vardı ve mortalitesi olmayan hastalarda splenomegali oranı oldukça yüksekti (%31'e karşı %6,4, p<0,001). Sonuç: COVID-19 özellikle erken dönemde akciğer tutulumu ile kendini gösterse de sistemik tutuluma da neden olur ve hedefteki organlarından biri dalak olabilir. Ayrıca hastaların başvuru anındaki lenfosit, monosit ve trombosit sayıları COVID-19'un ilerlemesini öngörebilir. Çalışmamızın sonuçları dalak boyutu artışının COVID-19 sonlanımı açısından dikkate alınması gereken bir belirteç olabileceğini düşündürmektedir.
P. Aeruginosa Bakterisinin Vitamin B Kompleksi ve Kırmızı Lazer Kullanılarak İnaktive Edilmesi
Authors: YURTTAŞ Asiye , ÇINAR Kamil
Published: November 2022

Son yıllarda anti-bakteriyel direnç olgusu, bakterilerin neden olduğu hastalıklarla mücadelede daha fazla sorun haline gelmiştir. Biz bu çalışmayla, açık yara ve yanıkların fırsatçı patojeni olan Pseudomonas aeruginosayı daha etkili bir yöntemle inaktive etmeyi ve fotodinamik inaktivasyon(PDI) gelişimine katkıda bulunmayı hedefledik. Pseudomonas aeruginosa bakterisini, vitamin B kompleksi ve lazer ile inaktive olduğunu spektrofotometrik ölçümler ve antimikrobiyal madde etkinliği analiz yöntemleriyle gösterdik. Ayrıca PDI'nin bakteri üremesi üzerindeki etkisi hem kalitatif hem de kantitatif olarak değerlendirilmiştir. Escherichia coli ve Pseudomonas aeruginosa suşları karşılaştırılarak ölüm oranları belirlendi. Koloni oluşturma birimi oranlarında Escherichia coli bakteri suşlarının karanlık ve ışık deneyinde vitamin B kompleksinin 0,25 mg/mL ve 0,125 mg/mL konsantrasyonlarında % 20’lik bir ölüm oranı görülmüştür. Pseudomonas aeruginosa bakteri suşlarının karanlık deneyinde vitamin B kompleksinin 0,5 mg/mL ve 0,125 mg/mL konsantrasyonlarında çok az bir ölüm oranı görülürken lazer maruziyet sonrası ölüm oranları sırasıyla % 60 ve % 50 çıktığı görülmüştür. Bu ölüm oranlarını doğrulama amaçlı akış sitometresi canlılık deneyleri yapılmış ve çıkan sonuçlar birbiriyle paralellik göstermiştir. Bu çalışmadan elde edilen veriler ışığında; kırmızı lazer diyotun, vitamin B kompleksi ile birlikte Pseudomonas aeruginosa bakterisinin inaktivasyonu için uygun bir aday olduğunu öngörmekteyiz. Yaptığımız bu çalışma, bakteriyel enfeksiyonların tedavisi için hastane, tıp ve mikrobiyoloji alanlarında yapılacak alternatif tedavi yöntemlerine ışık tutacaktır.
Serum Metalloproteinase-2 and Tissue İnhibitor Metalloproteinase-1 Levels As a Biomarker in Patients With Osteoarthritis Due To Brucella İnfection
Authors: GÜZEL Mustafa , AKPINAR Orhan , AYYILDIZ Veysel  Atilla , ŞİRİN Mümtaz Cem
Published: November 2022

Objectives: It was aimed to investigate the usability of MMP-2 and TIMP-1 levels as biomarkers in the oosteoarticular complications of brucellosis. Methods: The subjects were categorized into three groups as the healthy control group, brucella group, and brucella patients with osteoarticular involvement groups. Before medical treatment, serum samples from patients and control groups were stored at -80ºC until the day of study. MMP-2 and TIMP-1 serum levels were quantified by the ELISA method.Results: Serum level of MMP-2 (mean ± SD) in healthy control group was 1.71 +/- 0.10 ng / mL. Brucella patient group and Osteoarticular complıcation group were 14.3 +/- 2.52 ng / ml 20.65 +/- 2.33 ng / ml respectively (p=0.001). The mean TIMP-1 level in the control group was 3578.96 +/- 67.2 ng / mL, while in the Brucella group, this rate was 998.27 +/- 66.7 ng / mL and in the bone involvement group, 1656. 17 +/- 17.3 ng / ml. The difference between the control group and the brucella patients and the complicated group was statistically significant (p= 0.001). Conclusions: We think that the significant change in serum levels of MMP-2 and TIMP-1 when evaluated together with the radiological method, can be used as a biochemical indicator of the development of osteoarticular complications.
Reconstructive Surgery of Ulnar Claw Hand in Leprosy Patients by Lasso Procedure
Authors: Mahapatra Dr. Pratik , Reddy Dr. Vijay Narasimman
Published: November 2022

Leprosy, Hansen's disease caused by mycobacterium leprae, is widely known. Though there has been a substantial achievement in recent years given eliminating the disease, the deformity caused by the disease needs to be managed by reconstructive surgery. The ulnar nerve being superficial, is the most common nerve affected. When affected, the muscles innervated by the nerve begin to weaken, leading to a disparity between the strong extrinsic muscles and the weakened intrinsic muscles and is characterized clinically by metacarpophalangeal joint hyperextension and flexion of the proximal and distal interphalangeal joint. Doing reconstructive surgery on these patients will help them carry out day-to-day activities and reduce social awkwardness. Corrective surgeries like modified Stiles-Bunnell transfer, extensor carpi radialis graft, Zancolli lasso procedure, and palmaris longus tail graft are known to us. Out of all, the Zancolli lasso procedure was chosen for operating on all our cases because all other surgeries need high precision with proper training and proper post-operative physiotherapy. The study aims to evaluate the functional outcome of patients with leprotic ulnar claw hand operated with the Zancolli lasso procedure. Objectives assessed were deformity correction, grip strength, and range of motion. During the last two years, ten patients with ulnar claw hands came to Sree Balaji Medical College and Hospital, Chennai. They were operated on with the Zancolli Lasso procedure with adequate results. The zancolli procedure is easy to do and can be done in small centers, which restores finger flexion and doesn’t harm other superficialis tendons, thus preventing swan neck deformity of the fingers.
“Five F” on Prevention of Disease Transmission Among Mothers of Under Five Children
Authors: Mahalakshmi B. , Kandarpkumar Patel Arpit , Subramanian N. Siva , Prakash D.
Published: November 2022

The pathogenic microorganisms that cause infection, such as "bacteria, viruses, parasites, or fungus," can spread from one person to another either directly or indirectly. Infection spreads through direct contact from person to person, contact of body fluids, any secretions or even the fomite used by the infected person. The oral fecal route can be summarized into five f: - finger, food, fluid, feces, and flies. The Aim and objective of the study were to assess the knowledge regarding Five 'F' diseases transmission among mothers of under-five children to evaluate the effectiveness of sensitization program on knowledge regarding Five 'F' of disease transmission among mothers of under-five children and to find out the association between post-test knowledge scores and selected demographic variables among mothers of under-five children. "Pre-experimental research design" was used for the study and data were collected from 60 under five mothers by "nonprobability convenient sampling method", through a structured knowledge questionnaire. Data were analyzed using "descriptive and inferential statistics" such as standard deviation, mean, and chi-square tests. The mean post-test knowledge score (22.62±3.37) was higher than the mean pretest knowledge score (13.3±3.30). The calculated value (15.28) was more significant than the table value (1.67) at 0.05 level of significance, that shows the sensitization program was effective in increasing the knowledge regarding the prevention of "Five f" (finger, food, fluid, feces, flies) diseases transmission among mothers of under-five children.
Synthesis and Evaluation of Mutual Azo Prodrugs of Sulfamethoxazole and Salicylic Acid Derivatives for Colon Targeted Release
Authors: Kumar Anoop , Mishra Ashutosh
Published: November 2022

Several adverse effects are related to medications that treat moderate to severe inflammatory bowel diseases (IBDs). Targeted drug administration is necessary to treat inflammatory bowel disease to maximize efficacy and minimize toxicity. This study investigated the prodrug approach for antibacterials that target the colon. We chose sulfonamide (Sulfamethoxazole) as an antibiotic to target the colon. The prodrug approach is one of the most effective treatments for inflammatory bowel disease (IBD), and this mutual azo prodrug might serve the same function. This investigation aims to synthesize mutual azo prodrugs (S1-S5) and evaluate the colon-targeted release (in-vitro and in-vivo release studies). The objective of synthesizing mutual azo prodrugs (S1- S5) is that due to the high molecular weight of synthesized prodrugs (>500), they will enter the colon intact and not be absorbed in the upper GIT (Lipinski rule of 5). A coupling reaction between the sulfamethoxazole diazonium salt and salicylic acid derivatives allowed for synthesizing of mutual azo prodrugs (S1-S5). By monitoring the chemical reactions, the purity of the synthesized prodrugs was assessed, and by using FTIR, NMR (1H and 13C), Mass Spectrometry (MS), and Elemental Analysis, the structures of newly synthesized mutual azo prodrugs (S1-S5) were analyzed. Studies on the in-vitro stability of synthesized prodrugs showed less release after 6 hours in HCl buffer (pH 1.2), and only 10% release after 6 hours in phosphate buffer (pH 7.4) was observed. The sensitivity of the synthesized azo prodrug to the bacterial enzyme azoreductase was shown by incubating the azo prodrugs with the cecal contents of a rat; the release results showed that the release of free drugs from the azo prodrugs was more than 80%. Using trinitrobenzene sulfonic acid (TNBS)-induced colitis rats model, the in-vivo study was evaluated, and results revealed that mutually synthesized azo prodrugs are effective as 5-aminosalicylic acid in ulcerative colitis. Based on the release studies results, it is concluded that the azo prodrugs are a potential therapeutic target for ulcerative colitis.
Introduction (to the Special topic of the issue: Food Supply Problems in Regions)
Authors:   Marjani Institute of History of the Tatarstan Academy of Sciences, Khanipova Ilnara I.
Published: November 2022

The thematic compilation “Food Supply Problems in Regions” timed to coincide with the 100th anniversary of the tragic events in the history of the Soviet state – the mass famine in the Volga and Ural regions, which engulfed the territory of the young Tatar Republic. At the roundtable discussion held in Kazan on October 19, 2021, researchers from Kazan, Samara, Penza and Moscow discussed the features of food policy and the problems of food supply in the Soviet period in the Volga and Ural regions. The rubric includes some articles of the roundtable discussion participants.
General overview of humanitarian aid of the German Red Cross to the starving population of Soviet Russia and Ukraine in 1921–1923
Authors:   Samara State University of Social Sciences and Education, Tsidenkov Grigoriy G.
Published: November 2022

The article is based on documents from Russian national and regional archives, as well as modern scientific publications. It highlights and summarizes the main aspects the German Red Cross activities on the territory of Soviet Russia and the Ukrainian Soviet Socialistic Republic during the famine of 1921–1923. The German Red Cross was one of the member organisations of the Nansen International Committee for Aid to Famine in Russia and Ukraine and acted on its behalf independently, sending its own expedition to areas affected by famine and epidemics. Despite the quite unfavourable economic situation in Germany, humanitarian activities of the German Red Cross were conducted in several directions simultaneously: direct assistance to the starving population with food and clothing; healthcare; assistance to the Soviet healthcare authorities in carrying out the vaccination campaign; disinfection of infectious premises; assistance to Soviet scientists and educational institutions; delivery of medical equipment and deployment of scientific laboratories. Missions and representations of the German Red Cross worked in the Volga Region, eastern and southern Ukraine, the Autonomous Republic of Crimea, the cities of Petrograd, Moscow, Novorossiysk and Minsk. The contribution of the German Red Cross workers was marked with praise at the highest level by the Soviet leadership. Their energy and dedication are evidenced both by the results of their work and by the suffering and human losses they endured together with Soviet citizens.