bluuebunny/crossref_metadata_2025 huggingface dataset:
High-mobility 4 μm MOVPE-grown (100) β-Ga2O3 film by parasitic particles suppression
Authors: Chou Ta-Shun , Seyidov Palvan , Bin Anooz Saud , Grüneberg Raimund , Rehm Jana , Tran Thi Thuy Vi , Fiedler Andreas , Tetzner Kornelius , Galazka Zbigniew , Albrecht Martin , Popp Andreas
Published: January 2023

Absrtract

In this work, we comprehensively investigate the development of unwanted parasitic particles in the MOVPE chamber while growing μm level films. The density of the parasitic particles is found to be pronounced at film thicknesses starting from >1.5 to 2 μm. These particles seem to induce structural defects such as twin lamellae, thereby harming the electrical properties of the grown film. The origin of the parasitic particle is attributed to the parasitic reactions within the chamber triggered by the promoted gas-phase reactions during the growth process, which can be largely reduced by increasing the total gas flow and decreasing the showerhead distance to the susceptor. A film thickness of up to 4 μm has been achieved after minimizing the density of parasitic particles. Thereby, RT Hall measurements reveal carrier mobilities of 160 cm2V−1s−1 at carrier concentrations of 5.7 × 1016 cm−3.
Ultrasonic focusing using a stacked thin-plate region
Authors: Fukuchi Takaaki , Hayashi Takahiro , Mori Naoki
Published: January 2023

This paper describes a stacked thin-plate region for focusing the transmitted waves. The region was designed to focus the wave field in the bulk medium by utilizing the dispersion nature of Lamb waves. The first numerical calculation proved that an incident plane wave changes the wavefront in a stacked thin-plate region because of the different phase velocities in plates with different thicknesses, and the resulting transmitted wave was focused at the target. Second, when a delayed longitudinal wave was applied to the edge of the stacked thin-plate region with identical thickness, the numerical calculations showed that the delayed wavefront of the S0 mode was preserved in the stacked plate region, and that the transmitted longitudinal wave was appropriately focused at the target. The focusing devise consisting of a stacked thin-plate structure is useful for the buffer for phased array inspection.
4 and 7 GHz solidly mounted thickness extension mode bulk acoustic wave resonators using 36°Y LiNbO3
Authors: Kadota Michio , Yamashita Fuyuko , Tanaka Shuji
Published: January 2023

This paper describes 4 and 7 GHz solidly-mounted structure bulk acoustic wave resonators (SM-BAWRs) using LiNbO3 (LN) thin plates. A Bragg reflector solidly supports the LN thin plate. The two kinds of SM-BAWRs use thickness extension mode in 0.81 and 0.5 μm thick 36°Y LNs. The Bragg reflector is made of Al or SiO2, and Ta films. The 0.81 μm thick LN SM-BAWRs with each acoustic layer thickness 0.23 wavelength (λ), which is almost optimum thickness, exhibited resonance frequency (f
r) of 3.84 GHz, antiresonance frequency (f
a) of 4.17 GHz, a bandwidth of 8.4%, an impedance (Z) ratio of 54 dB, and coupling factor k
t
2 of 17.7%. Despite using an acoustic film 0.12λ much thinner than the optimum thickness, SM-BAWR using the 0.5 μm thick LN exhibited f
r of 6.86 GHz, f
a of 7.15 GHz, and Z ratio of 37 dB. Those results suggest a high potential for this device.
Two-stage optical trapping and assembling of protein at air/solution interface
Authors: Yi Po-Wei , Chiu Wei-Hsiang , Toyouchi Shuichi , Bresolí-Obach Roger , Hofkens Johan , Chatani Eri , Hosokawa Yoichiroh , Sugiyama Teruki , Masuhara Hiroshi
Published: January 2023

Optical trapping at interfaces has recently gained relevance due to the expansion of optical potential far away from the focus, especially for proteins where submillimeter structures have been described. Initially, lysozyme clusters are trapped as a shallow layer at the surface, becoming thicker with irradiation time. Nonetheless, overcoming a concentration threshold, lysozyme clusters inside the solution are collected and transported toward the focus, invading the lysozyme layer, which results in a border between them, although no concentration jump is detected. This two-stage optical trapping occurs due to the long-range interaction originating from the focus.
Thioxanthone-containing blue thermally activated delayed fluorescent emitter
Authors: Kanno Natsuko , Ren Yongxia , Kusakabe Yu , Suzuki Katsuaki , Shizu Katsuyuki , Tanaka Hiroyuki , Wada Yoshimasa , Nakagawa Hiromichi , Geldsetzer Jan , Kaji Hironori
Published: January 2023

Accelerating reverse intersystem crossing (RISC) without sacrificing fast radiative decay is effective in suppressing efficiency roll-off (eRO) in thermally activated delayed fluorescence (TADF)-based organic light-emitting diodes. We here report a TADF emitter, CC-TXO-I, combining a bicarbazole donor (CC) and a sulfur-containing acceptor (TXO). The CC is used to accelerate radiative decay via moderate donor-acceptor torsion angle, and the TXO is expected to provide fast RISC by the heavy-atom effect. We realized very large rate constants of RISC (k
RISCs) of ∼107 s−1. Both k
RISCs and rate constants of radiative decay of CC-TXO-I increased with increasing doping concentration, resulting in improved eROs.
Adverse reactions to antiarrhythmic drugs
Authors: Do Ungjeong
Published: January 2023

There are various types of adverse reactions to antiarrhythmic drugs (AADs). Proarrhythmia, which refers to an exacerbation of the preexisting arrhythmia or occurrence of a new arrhythmia, may occur under the therapeutic concentration of an AAD. Bradyarrhythmia is the most common type of proarrhythmia due to AADs, and prior myocardial infarction and old age are known risk factors. Atrial flutter with 1:1 atrioventricular conduction usually occurs during rhythm control of atrial fibrillation with class IC AADs. QT prolongation due to AADs, mainly class III AADs, elevates the risk of torsade de pointes by triggered activity due to early afterdepolarization. The addition of clinical factors that promote QT prolongation, such as hypokalemia, hypomagnesemia, female sex, and bradycardia, increases the risk of developing torsade de pointes. Proarrhythmic monomorphic ventricular tachycardia usually occurs as a result of slow conduction and disparity of refractoriness due to class IC AADs. In patients with preexisting left ventricular systolic dysfunction or structural heart disease, the risk of hypotension or cardiogenic shock caused by negative inotropic effects due to AADs should be considered. To prevent these major adverse reactions to AADs, we need to understand the electrophysiologic properties of AADs in detail. Furthermore, the risk of proarrhythmia could be heightened by interplay with clinical factors, such as electrolyte unbalances, heart rate, and hepatic/renal or myocardial dysfunction. Sufficient awareness about drug-drug interactions, which may affect the metabolism of AADs, will improve patient safety during the management of arrhythmia.
Corporate social responsibility pyramid in Ethiopia: A mixed study on approaches and practices
Authors: Kusakci Sumeyye , Bushera Ibrahim
Published: January 2023

This paper examines CSR approaches and practices of local firms in Ethiopia, where the state is still a key player in business life. Moreover, it assesses at which stage Ethiopian CSR is. This mixed-method study includes quantitative analysis through SPSS and qualitative content analysis. A revised CSR practices scale has been conducted on owners/managers and employees of 100 local companies in Ethiopia. Besides, the companies' official websites have been thoroughly reviewed using five variables to understand their CSR approaches and practices better. The findings reveal that Ethiopian companies practice CSR though it is at the stage of fragmented CSR and the priorities differ from the global trend. Most respondent companies generally have excellent legal practices and CSR practices toward employees and customers. However, philanthropy, social sustainability, and management of CSR are remarkably at a mediocre level. Content analysis shows similarity with the results of quantitative study, to the exclusion of philanthropy. Notably, the hierarchy derived from our research varies also with Visser's CSR model.
Internal corporate governance mechanisms and firm performance: 3SLS empirical evidence from Thailand
Authors: Silpachai Kobsidthi
Published: January 2023

This paper aims to examine the effect of corporate governance (CG) on firm performance (FP). The 3SLS (Three-Stage Least Squares) regressions were performed on a system of equations based on a panel dataset of 1,768 firm-years of Thai-listed companies from 2014 to 2020. This is to assess the simultaneous linear/curvilinear relationships between CG and FP. We found that internal CG mechanisms (i.e., the board size, institutional ownership, and dividend policy) are significantly related to firm performance measured by return on equity (ROE), return on assets (ROA), and price-to-book ratio/Tobin’s Q (PBR). Board size exhibits a curvilinear relationship rather than a linear relationship with FP. This reflects the integration between resource dependency theory and stewardship theory. Relative to ROE and ROA, a board size of 10 is optimal (which is associated with a peak ROE of 14.8% and a peak ROA of 3.4%. A board size greater than ten would see a fall in ROE and ROA. Relative to PBR, a board size of 12 is optimal, with a peak PBR of 2.39 times. This study further identifies a ranking of effective CG mechanisms.
Seller loyalty of Shopee marketplace community: Community study in Shopee Bekasi campus
Authors: Triningsih Susinta , Iswanto Heri , Hadi Prasetyo
Published: January 2023

This study aims to analyse seller loyalty through community marketing and seller satisfaction. This study employs a method with a sample of 135 sellers from the Shopee Campus community in Bekasi. Research data were obtained through questionnaires distributed to the sample and analysed using SmartPLS 0.3. The results showed that community marketing significantly positively affected seller loyalty. Thus, community marketing has a significant positive effect on seller satisfaction. Moreover, seller satisfaction has a significant positive effect on seller loyalty. In contrast, community marketing through seller satisfaction positively affects seller loyalty.
Psycho-pedagogical recommendations for the re-education of people prone to criminality due to thermal stress (cold) and psycho-pedagogical support for potential victims
Authors: Cebotari Stanislav
Published: January 2023

In this article are described deliquent behaviours caused by thermal stress ( the cold) and its influence upon human’s personality. The purpose of this publication is to give psychopedagogical recommendations for the specialists who teach people who are predisposed of committing acts of violence because of thermal stress and psychopedagogical support for potential victims.
Methodological aspects regarding the explanation of the predictions programming within the discipline of artificial intelligence
Authors:   Ion Creanga Pedagogical State University, Republic of Moldova, Braicov Andrei
Published: January 2023

The study of linear regression in high school opens up opportunities for examining a range of practical problems and can form an object of study within the optional discipline Artificial Intelligence, but also within the modules Numerical Calculus, Applications of the Derivative. The article presents methodological considerations for explaining the programming of predictions with the help of linear regression through the reasoned identification of the regression function, the elaboration of the implementation algorithm or by capitalizing on the tools of a spreadsheet.
The concept of the "Informatics Didactics" university course
Authors:   Alecu Russo State University of Balti, Republic of Moldova, Cabac Valeriu
Published: January 2023

In the article, a modern vision of the "Informatics Didactics" university course is proposed for discussion. The object of study of didactics is considered the "didactic relationship", which connects a teacher, a student and a content. The didactic relationship can be visualized through the didactic triangle. The latter "dictates" the structure of the course.
Scientific thinking in the real sciences and humanities
Authors: Sanduleac Sergiu
Published: January 2023

This paper describes the concept of developing and streamlining scientific thinking in the humanities and real sciences. The problem of the direction of thinking of scientific gardening according to the field of study is addressed. In the paper, reference is made to various existing theories regarding scientific reasoning, problem types, heuristics, inventive problem-solving algorithms, and an analysis of the route is attempted from the perspective of the theories presented by D. Klahr, D. Lenat, Kr. Moritz, G. Altshuller, R. Paul, B. Noel and others. The paper concludes with a conceptual model proposed by the author based on the analysis of specialized literature. Based on the outlined methodological benchmarks and the theoretical approaches presented regarding the development and efficiency of scientific thinking among teachers from different fields, a set of strategies was proposed to improve the efficiency of scientific thinking among teachers universally applicable both from the perspective of the humanities and from the perspective of real sciences. Finally, the problem of the development of scientific thinking both from the perspective of humanities and real sciences is solved from this perspective.
A Morphological Analysis of Martin Luther King Jr’s “I HAVE A DREAM” Speech: a Compositional Semantic Perspective
Authors: André Datondji Cocou
Published: January 2023

This research work has investigated the importance of linguistic morphology in the construction of new lexemes and grammatically conditioned words on the first hand and the way both derivational and inflectional morphemes function to carry and impart compositional meaning in text on the other. Premised on the objective of raising more awareness on the significance of morphological research, this paper has applied both the quantitative and qualitative analysis methods to the historic speech “I Have a Dream” by the African American civil rights figurehead Martin Luther King Jr. The scientific roadmap thus carved has led its process through the identification, labelling and numbering of the distinctive derivational (50 /40%) and inflectional (75 / 60%) morphemes. A furthering of the quantitative input has displayed an outstanding use of nominalisations with nouns derived from adjectives 17 [13.6%] and from verbs 12 [9.6%] with bound morphemes such as “ity”, “ice”, “ation”, “tion”, “or”, and “dom”. On the inflectional part, the prevailing use of regular and irregular plural number imparting morphemes (47 / 37.6%) together with tense inflections (16 / 12.8%) pair up to confirm, in a qualitative analytical approach, the ideological perspective of the speaker to include the largest anonymous members of the African American community as the intended beneficiaries of his unquenchable soft but vibrant battle for freedom. The use of tense indicating morphemes has revealed the presence of a threefold tense progression from the past tense (simple past and past perfect) to the simple present and then to the future. The crosscheck of the semantics of such morphemic operations has uncovered the perspective of Martin Luther King Jr for the logical representation of the sufferings of the Black community and liberation struggles in the past, the need to keep the battle going in the present time with the conviction of brighter days in the future.
Garlic Extract Enhances the Peripheral Blood Cellular Immune Responses in Male ICR Mice
Authors: Khalil Atef M. , Maher Zainab M.
Published: January 2023

We investigated the effects of garlic extract on the peripheral blood immune cells in mice treated with the extract for twenty days. The study was carried out on ten male ICR mice. The mice were divided into two groups. The control group received a distilled water and garlic extract group in which the mice received garlic extract at a dose of 500 mg/kg. b.w, for twenty days. Blood samples were collected on day ten and day twenty post inoculation (p.i) for differential leucocytic count (WBCs count and Lymphocytes %) and flowcytometric analysis. In comparison to the control group, garlic extract treatment induced a significant increase in WBCs count and lymphocytes percentage on day 10 and day 20 p.i. Furthermore, garlic extract administration to the experimental mice caused significant increase in the expression percentage of CD4, CD8 and γ-δ T cells when analyzed by flowcytometry on day 10 and increased dramatically on day 20 p.i. The WBCs count and lymphocytes percentage as well as the percentage of the expressed cells increased on day 20 more than their levels on day 10 p.i with a fixed dose of garlic extract. In conclusion, inoculation of garlic extract induced an increase in the immune responses of the cellular immunity in the peripheral blood circulation of mice. Scholars Middle East Publishers
Gender-Based Preponderance of Commonly Observed Surgical Cases Presenting at a Referral Health Facility in Southern Nigeria
Authors: E. Udosen J. , C. Akwiwu E. , U. Akpotuzor D. , O. Akpotuzor J. , A. Abunimye D.
Published: January 2023

Surgical operations constitute an integral part of medical management of different health challenges. Developing countries suffer from under-reporting of health conditions even when such conditions are fairly common in occurrence. This study observed common surgical cases with a view to highlighting possible associations with gender. A retrospective cross-sectional descriptive approach was adopted. A total of 626 cases presenting for surgical review between a two-year periods from September 2020 to August 2022 at University of Calabar Teaching Hospital, Calabar in Nigeria were reviewed. Data analysis to test for gender association was carried out using chi-square analysis on SPSS 22.0 at 95% confidence level with p-value of ≤ 0.05. The highest frequency of 56% was recorded for breast tumour. This was followed by hernia and goitre which accounted for 20% and 15 of surgical cases respectively. Lesser frequencies were observed for lipoma (4%), appendicitis (2%) and fistula (2%). The least among the commonly observed cases was testicular torsion which was recorded to be 1%. Breast tumour and goitre were significantly higher in females compared to males, while hernia was seen to be significantly higher in males compared to females. Testicular torsion occurred solely in males. This study concludes that significant gender associations exist in the distribution of surgical cases at the study centre. While female preponderance was observed for breast tumour and goitre cases, hernia was prevalent among the males.
A z alvajdák megyei bíráskodása Szentimrén
Authors: W . Kovács András
Published: January 2023

A 14. század elejétől a 15. század első harmadáig az erdélyi alvajdák, mint az erdélyi vajdák helyettesei, Szentimrén (románul: Sântimbru) végeztek bírói tevékenységet a legfontosabb vallási ünnepek oktávján (azaz nyolcadik napján). Ebben a minőségükben ítéleteik a vajdasági igazságszolgáltatás részét képezték. Ugyanebben az időszakban az alvajdák Fehér (rom.: Alba) megye grófi (comes, magyarul: ispán) tisztségét is betöltötték, és a megye két nemesi bírájával (iudices nobilium, magyarul: szolgabíró) együtt megyei bíróságot (sedes iudiciaria, azaz szedria) tartottak az adott megye nemessége számára, hasonlóan az egyházi ünnepek nyolcadik napján. Az alvajdái és a megyei bíróságot minden bizonnyal egy időben tartották, és az Fehér megye ispánjaként a alvajdák által kiadott oklevelek néha a alvajdái joghatóság alá tartozó intézkedéseket is tartalmaztak. 1431 és 1440 között az alvajdai bíróságot felváltva Szentimrén és Tordán (rom.: Turda) tartották, de 1440 után az előbbi településről mint alvajdai bírósági tevékenység helyszínéről lemondtak. Mivel az alvajdák már nem ezen a helységben ítélkeztek, megszűntek Fehér megye grófjai is (ettől kezdve a vajda egy ispánt nevezett ki a megye élére). Ennek ellenére a Fehér megyei sedes iudiciaria továbbra is a vallási ünnepek nyolcadik napján tartotta üléseit, ellentétben a többi erdélyi megye törvényszékeivel, amelyek két-három hetente, a hét ugyanazon napján üléseztek.
„Ennek előtte Lazar Mihali Uram fi anak fogadta vala Deli Farkas Uramat” : Deli Farkas és az abrudbányai bányák
Authors: Mátyás-Rausch Petra
Published: January 2023

Ez a cikk egy kincstári tisztviselő - Deli Farkas - motivációit kutatja, hogy saját jobbágya örökbefogadja. Ezt még a Lázár Mihályhoz hasonló jobbágyok esetében is számos ok indokolhatta, például ásványkincsbirtokai, az a törvényes kiváltság, hogy abrudi polgárként - bár bizonyos korlátozásokkal - végrendeletében szabadon rendelkezhetett bányáiról és egyéb birtokairól. Lázár Mihály élete bizonyíték arra, hogy az Erdélyi Fejedelemség területén a bányászat nemcsak a kiváltságos társadalmi csoportok, hanem a jobbágyok számára is kínált bizonyos lehetőségeket a társadalmi és gazdasági felemelkedésre.
„Az ördögnek ögyéb madara nincs, mind a páva.” A magyar és a közép-eurázsiai duális teremtésmondák (A810, A812, K483) összefüggéseiről : Kálmány Lajos (1852–1919) és Bosnyák Sándor (1934–2020) emlékére
Authors: Mátéffy Attila
Published: January 2023

Jelen tanulmány egyfelől azt vizsgálja, hogy ’Az Ördögnek ögyéb madara nincs, mind a páva…’ (MNK 770. II. 3-4.) magyar eredetmagyarázó mondáknak milyen konceptuális és történeti kapcsolata van a dualisztikus világteremtési mondacsoporttal (A812), amelynek a Kárpát-medencében 17 magyar változata ismeretes, másfelől annak lehetőségét tárgyalja, hogy létrejöhettek-e a manicheista és jezidi vallási közösségek, valamint a félnomád korai magyar csoportok között Közép-Eurázsiában, mindenekelőtt Horászán és a Kaukázus vidékén a 8–9. századok folyamán vallási-kulturális kapcsolatok, amelyek a kérdéses magyar mondákat meghatározó vallási elképzelést eredményezhették, hogy a páva az ördög madara. A tanulmány szerzője áttekint még egy ideológiai természetű prekoncepciót, amely az utóbbi fél évszázad során uralja a duális világteremtési mondák diskurzusát a magyar folklorisztikában. Vizsgálata során a szerző a történeti-összehasonlító folklorisztika és a diskurzusanalízis módszertanát alkalmazza.
Szent László Torda-vidéki hagyományköre
Authors: Magyar Zoltán
Published: January 2023

Szent László király (1077‒1095) a középkori Magyarország egyik legnépszerűbb szentje volt, kultusza a teljes magyar nyelvterületen elterjedt. Neve és alakja a magyar kulturális emlékezetben Erdély védőszentjeként is ismert. Szent László népi tisztelete búcsújáró hagyományok és mondák formájában számos erdélyi tájegységen még a 19‒20. századot is megélte. Mint azt már a 15‒16. századi adatok is megörökítik, változatos Szent László-mondakör alakult ki a középkori Erdély egyik központjának számító Torda vidékén, összefüggésben a város közelében lévő Tordai-hasadékkal, amelynek eredetét a legendás királynak tulajdonította a környékbeli nép. E tájegységen Szent László király mondakörének része a vízfakasztás csodája, a kővé vált pénzek mondája, a sziklában megmaradó nyomok motívuma, továbbá több más helyi hagyomány és vándormonda is.
Az „istenküldötte” ember a népmesében
Authors: Bálint Péter
Published: January 2023

Az Isten fia kifejezés ritkán fordul elő a népmesékben, a mesemondók inkább az istenküldötte emberről beszélnek. Az istenfiúság elvont fogalom számukra, bár sejtik, hogy a Messiást vagy egy prófétát kell érteni rajta. A narratívákban megkülönböztetjük az istenküldötte embert a segítő lénytől. Egyfelől másként definiálják magukat, másfelől a hőssel folytatott diskurzusokban is mindkettő másként viselkedik.
EVALUASI PENGELOLAAN OBAT DI PUSKESMAS KAYU TANGI BANJARMASIN
Authors:   Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Wahyuni Amaliyah , Reda Reda ,   Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Aisyah Noor ,   Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Ilahi Fitrah Shafran ,   Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
Published: January 2023

Drug management is one of the pharmaceutical service activities. Drug management is important and needs to be done well, because good drug management will ensure the continuity of availability and affordability of effective, efficient and rational drug services. This study aims to determine the management of drugs at the Kayu Tangi Health Center Banjarmasin and the factors that cause discrepancis. This research is a non-experimental descriptive research conducted prospectively and retrospectively. Collecting data using observation sheets based on pharmacy SOPs at the Puskesmas. The population and sample are all data on drug management which includes planning, demand, receipt, storage, distribution, control, administration and reporting at the Kayu Tangi Health Center Banjarmasin in February – April 2022. Data analysis was carried out by calculating the percentage of conformity. The results showed 96% of the activities were in accordance with planning, requesting, receiving, distributing, controlling, administrative and reporting activities. While 4% is not appropriate, which includes storage activities. Factors that are not arranged alphabetically and pharmacologically due to insufficient space for the storage of these drugs.
UJI INVIVO AKTIVITAS DIURETIKA EKSTRAK ETANOL 70% DAUN UNGU (Graptophyllum pictum (L) Griff) PADA MENCIT PUTIH JANTAN GALUR WISTAR
Authors:   Universitas Qamarul Huda Badaruddin, Umboro Recta Olivia , Bimmaharyanto Dedent Eka ,   Universitas Qamarul Huda Badaruddin, Apriliany Fitri ,   Universitas Bumigora, Dewi Iva Rinia ,   Sekolah Tinggi Ilmu Kesehatan Ibnu Sina Ajibarang
Published: January 2023

Traditionally, daun ungu plant (Graptophyllum pictum (L) Griff) has been known to have pharmacological effects that can help with a variety of health issues. This plant’s flavonoid compounds content is thought to have diuretic activity in this plant is believed to have activity. The purpose of this study is to determine the diuretic activity and optimal dose of etanol extract of 70% daun ungu administered orally to male white mice. This is an experimental study with a completely randomized design (CRD) that includes 1 negative control group (Na.CMC 0.5%), 1 positive control group (furosemide 40 mg) and 3 test groups of 70% daun ungu ethanol extract doses of 10 mg/kg BW, 25 mg/kg BW and 40 mg/kg BW with urine volume test parameters. One-way ANOVA and Kruskal-Wallis statistical test were used to analyze the data. The results showed that one-way ANOVA revealed a P < 0.05 (0.012), and P ≤ 0.05 (0.051) for the Kruskal-Wallis test. It can be concluded that 70% daun ungu etahanol exctract has effective diuretics, with an optimal dose of 40mg/Kg BW providing an effect twice as large as the positive control (furosemide 40 mg).
UJI EFEKTIFITAS GEL KOMBINASI EKSTRAK DAUN BELUNTAS (Pluchea indica L. Less) DAN RIMPANG JAHE MERAH (Zingiber officinale Roscoe) TERHADAP BAKTERI Propionibacterium acne DAN Staphilococcus epidermidis
Authors:   Program Studi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan, Fatmi Mindiya , Wibowo Agung Eru ,   Fakultas Farmasi, Universitas Pancasila, Rahmat Deni ,   Fakultas Farmasi, Universitas Pancasila
Published: January 2023

Beluntas leaf (Pluchea indica L. Less) and red ginger rhizome (Zingiber officinale Roscoe) is a plan have activity as antibacterial causes acne. Beluntas leaf contain antibacterial compounds from alkaloid, flavonoid free type flavonol, steroid and tannin. Red ginger rhizome extract compounds flavonoid, essential oil, polifenol, and saponin. This study aim to develop gel product extract combination from beluntas extract and red ginger rhizome at concentration 1: 1; 1: 2 and 3:2 formulated in gel, then tested the physical characteristic and gel microbiology tested on P. acne and S. epidermidis. Beluntas leaf and red ginger rhizome extracted by maceration in ethanol 96%, and carbopol 934 as gel base. Physical characteristic test comprise homogeneity, organoleptic, pH, dispersion gel and viscosity. Microbiology tested use method diameter of inhibition zone with Medi-Klin Gel® as positive control. The result show homogeneous gel preparation, with brownish green color, ginger smell, pH 5,83-6,07, spreadability 5,1-5,7 cm, viscosity 690000 cp-1460800 cp. effect of adding extract beluntas leaf and red ginger rhizome to gel preparation, in both single and combination extracts. Antibacterial evaluation showed that formula 3 give the best effectiveness with 5,92 mm zone of inhibition against P. acnes and 4,15 mm against S. epidermidis
Penghantaran Obat melalui Kulit: Teknologi Vesikel Liposome dan Analognya
Authors: Rosalina Ajeng Illastria , Sagita Erny , Iskandarsyah
Published: January 2023

Pengembangan teknologi farmasi selalu didorong untuk mengatasi berbagai keterbatasan sediaan yang telah ada sebelumnya. Salah satunya adalah teknologi penghantaran melalui rute transdermal yang memiliki berbagai keuntungan dibandingkan rute lain. Namun, dibalik keuntungan tersebut, penghantaran melalui jalur transdermal juga memiliki banyak hambatan dalam menghantarkan zat aktif. Salah satu hambatan tersebut adalah struktur kulit yang kompleks sebagai barier tubuh, sehingga diperlukan teknologi untuk mengatasi permasalahan tersebut. Salah satu solusinya adalah dengan peningkat penetrasi. Liposom merupakan sistem peningkat penetrasi yang banyak dieksplorasi karena kemampuannya menghantarkan obat hidrofilik dan hidrofobik. Berbagai pengembangan dilakukan untuk meningkatkan kemampuan struktur ini dengan variasi bahan dan metode pembuatan yang menghasilkan variasi karakteristik sistem ini. Dalam kajian ini, penulis membahas berbagai generasi baru liposom terkait keunggulan dan keterbatasannya serta metode pembuatan dan evaluasi sediaannya.
Severe Preeclampsia Complicated by Placental Abruption Leads to Fetal Distress
Authors: Hapdijaya Indra , Suryawan Aloysius , Tessalina Ecclesia , Herdiana Elisabeth Mariska Natasha , Natalia Janice , Setya Dewa Brata Gede Anggara , Andrianto Hendrik , Jemarut Catharine Welanai , Devina Livia
Published: January 2023

Placental abruption is a common complication of preeclampsia. It is an obstetric emergency that occurs when the placenta partially or completely separates from the uterine wall. The diagnosis is usually made clinically or objectively. It is relatively rare but put a serious risk for both the fetus and the mother. We reported a case of a 32-year-old multigravid patient at 35-36 weeks gestation who presented with moderate vaginal bleeding and lower abdominal pain. Her obstetric history included one premature vaginal delivery. Her blood pressure started to rise in the second trimester of pregnancy. The examination revealed that her blood pressure was 190/120 mmHg, and she had pitting edema on her extremities and tender uterine fundus. The fetal heart rate was bradycardia at 100 beats per minute. Placental abruption and fetal distress were suspected. An emergency cesarean section was performed. Intraoperatively, the uterus showed intramural bleeding and was livid, with the beginning of Couvelaire-uterus. The uterus was left in situ. In conclusion, placental abruption interrupts the vital function of the placentae which leads to fetal hypoxia and even fetal death. It is an obstetric emergency that requires immediate intervention to save the fetus and reduce the risk of complications in the mother.
Pengaruh Daun Binahong (Anredera Cordifolia (Ten.) Steenis pada Proses Penyembuhan Luka
Authors: Hardiani Charissa Christa , Dewajanti Anna Maria , Kurniawan Hendrik , Sumbayak Erma Mexcorry
Published: January 2023

Luka dapat terjadi jika terdapat kerusakan integritas pada kulit. Pengobatan antiseptik, povidone iodine 10% sering digunakan untuk mempercepat penyembuhan luka, namun povidone iodine 10% dapat memberikan efek iritasi dan menghambat pembentukan fibroblas pada luka. Pengobatan herbal merupakan alternatif karena mudah didapat dan efek samping yang rendah. Daun binahong dikenal oleh masyarakat sebagai salah satu pengobatan herbal untuk mengobati luka atau mempercepat penyembuhan luka. Penelitian ini bertujuan untuk mengetahui pengaruh daun binahong terhadap proses penyembuhan luka. Subjek yang digunakan adalah tikus wistar (Rattus norvegicus) sebanyak 25 ekor, yang dibagi dalam 5 kelompok, yaitu kelompok kontrol negatif, kontrol positif (povidone iodine 10%), dan kelompok perlakuan (salep ekstrak daun binahong 10%, 20%, dan 40%). Tikus dilukai satu sayatan pada punggungnya dengan panjang 20 mm dan kedalaman 2 mm.  Kemudian dihitung jumlah sel fibroblas pada luka tersebut. Hasil uji statistik terhadap jumlah sel fibroblas, menunjukkan salep ekstrak daun binahong 40% memiliki nilai yang signifikan dalam proses penyembuhan luka. Sementara, berdasarkan panjang luka, terdapat adanya proses penyembuhan luka pada masing-masing kelompok namun tidak ada perbedaan yang signifikan antar kelompok. Kesimpulan pada penelitian ini adalah salep ekstrak daun binahong 40%, memiliki nilai yang signifikan dan terbaik dalam proses penyembuhan luka sayat.
Laporan Kasus : Pseudotrombositopenia pada Pasien Pre-Operasi
Authors: Singgih Gregorio Gavriel , Wijaya Jullyanny Waty , Adisuhanto Monica
Published: January 2023

Pseudotrombositopenia didefinisikan sebagai jumlah hitung trombosit rendah palsu yang terukur oleh faktor alat analisis hematologi. Diketahui EDTA-dependent pseudotrombositopenia merupakan salah satu penyebab trombositopenia dengan prevalensi 0,1-2%. Pseudotrombositopenia yang tidak terdiagnosis dapat menyebabkan kesalahan dalam keputusan klinis. Laporan kasus ini disusun agar dapat meningkatkan kewaspadaan dalam mendiagnosis pseudotrombositopenia. Laki-laki 56 tahun melakukan pemeriksaan pre-operasi dan didapatkan adanya trombositopenia dengan jumlah trombosit 16.000/uL tanpa ditemukan adanya kelainan pada parameter koagulasi lainnya dan tidak terdapat adanya perdarahan aktif, Pada pemeriksaan morfologi darah ditemukan banyak platelet clumping. Dokter menduga adanya EDTA-dependent pseudotrombositopenia lalu melakukan pengambilan sampel darah kembali satu hari kemudian dengan menggunakan antikoagulan natrium sitrat. Sampel darah tersebut diperiksa dengan mesin hematologi Sysmex XN-550 dan didapatkan jumlah trombosit yaitu 112.000/uL. Bila dijumpai kondisi jumlah trombosit rendah / trombositopenia tanpa ada tanda klinis pendarahan yang jelas, maka perlu dipertimbangkan adanya EDTA-dependent pseudothrombocytopenia. Pemeriksaan morfologi darah tepi dan pengulangan darah lengkap menggunakan sampel darah dengan antikoagulan lainnya, yaitu natrium sitrat menjadi salah satu metode dalam menegakkan adanya EDTA-dependent pseudothrombocytopenia.
Digital policy entails theorising and regulating a dynamic sector domestically and globally
Authors: Ndzendze Bhaso
Published: January 2023

2022 has been a landmark year in the development of digital technologies and decisions whose consequences will be with us for decades to come. The year has likewise seen government responses in the form of policies aimed at enhancing as well as regulating these innovations and trends, and at times appearing to be barely keeping up. Officials and legislators are increasingly learning-by-doing amid the rapid pace of digital change (thereby demonstrating the need for structural and theoretical thinking vis-à-vis digital technologies).
IMPACT OF STARTUPS IN INDIAN GDP IN 2022
Authors: Sneha CJ  , Vignesh B  , Dr. J. Krithika
Published: January 2023

Indian start-ups have made their mark on the global stage. The ecosystems rapid growth and maturity have unleashed a tremendous appetite for scalability, alternative funding options, global market expansion, and the ability to enable millions of jobs. This meteoric rise of start-ups has made India the worlds third largest start-up ecosystem, and it has had a significant impact on the Indian economy, demonstrating the ability to contribute approximately 4-5 percent of Indias GDP. This report aims to highlight the impact of start-ups on the Indian economy, as well as the ecosystems inherent ability to foster inclusivity, sustainability, and growth. Start-ups do not exist in isolation; rather, they are part of a larger corporate environment dedicated to developing solutions with significant social and economic impact. Because start-ups are incubators for cutting-edge inventions, they create jobs, which means more career opportunities; more employment leads to a stronger economy, and a stronger economy has a direct impact on the growth of cities where start-ups are located.
KEYWORDS: GDP- Gross domestic product; Start-ups; Unicorn; Financial benefits; Indian economy; Macroeconomics; Impact on economy; Indian business.
Sosialisasi Pemahaman Thaharah Dalam Perspektif Ekonomi Islam
Authors: Meriyati Meriyati
Published: January 2023

Kegiatan pengabdian masyarakat ini membahas tentang Pemahaman Thaharah Dalam Perspektif Ekonomi Islam pada guru dan staf SMA Bina Warga.  Metodelogi yang digunakan pada pengabdian kepada mayarakat ini berbentuk ceramah dan paparan langsung pada guru, staff dan karyawan, dengan tujuan  memberikan  sosialisasi  dan  pemahaman thaharah tidak hanya membahas mengenia ibadah amalia saja, namun dalam perekonomian juga pembahasan thaharah memiliki peran penting bagi diri individu. Hasil dari sosialisasi ini dapat memperoleh pemahaman makna dan dapat diterapkan dalam kehidupan sehari-hari. Sasaran pengabdian ini adalah seluruh guru dan staf SMA Binawarga dari segi pemahaman melalui persentase jenis kelamin laki-laki maupun perempuan.
Pelatihan Pengembangan Maggot sebagai Pakan Ternak di Desa Karang Tunggal, Kec Parenggean sebagai Model Kewirausahaan Sosial Masyarakat
Authors: Kaharap Yorgen , Dotrimensi Dotrimensi , Setiawan Ferry , Nasution Reny Puspita Sari
Published: January 2023

Populasi penduduk yang semakin bertambah berimbas pada meningkatnya kebutuhan masyarakat akan protein hewani yang berasal dari ikan. Hal ini secara langsung meningkatkan permintaan sumber protein hewani tersebut. Salah satu jenis sumber protein hewani yang banyak beredar di pasaran adalah ikan lele (Clarias batrachus). Selama ini, lele menyumbang 10% produksi perikanan budidaya nasional dengan tingkat pertumbuhan yang mencapai 17%–18%. Seiring dengan naiknya tingkat konsumsi muncul beberapa budidaya varietas baru yang kualitasnya lebih unggul. Terobosan yang telah dilakukan oleh Balai Besar ikan air tawar Sukabumi adalah menghasilkan varietas baru yakni Lele Sangkuriang. Ikan Lele Sangkuriang memiliki keunggulan mampu hidup dalam kepadatan tebar yang tinggi, tahan terhadap penyakit, memiliki rasio pemberian pakan berbanding pertumbuhan daging yang baik serta waktu panen yang cepat. mahalnya harga pakan ternak di Kalimantan Tengah sehingga perlu adanya solusi pakan ternak yang murah di dapat oleh sebab itu maka dianggap pengtuk untuk dilaksanakannya program PkM Pelatihan Pengembangan Maggot sebagai Pakan Ternak di Desa Karang Tunggal, Kec  Parenggean sebagai Model Kewirausahaan Sosial  Masyarakat. Usaha peternakan merupakan mata pencaharian utama bagi penduduk  di Desa Karang Tunggal, Kec  Parenggean yang hampir seluruh Penduduk, lebih dari 75% berprofesi sebagai petani dan peternak dengan berbagai tingkatan. Pengabdian melalui Pelatihan Pengembangan Maggot sebagai Pakan Ternak di Desa Karang Tunggal, Kec  Parenggean sebagai Model Kewirausahaan Sosial  Masyarakat. Metode yang digunakan adalah pelatihan tentang Pengembangan Maggot sebagai Pakan Ternak di Desa Karang Tunggal, Kec  Parenggean sebagai Model Kewirausahaan Sosial  Masyarakat. Hasil pengabdian ini menunjukan bahwa masyarakat dapat mengerti dan bisa memanfaatkan potensi sumber daya yang ramah lingkungan sebagai solusi dari alternative pakan ternak bagi  Masyarakat Desa di desanya serta memenuhi kebutuhan pakan ternak di Desa Karang Tunggal.
Pengelolaan Chips Kusang ( Keripik Kulit Pisang) Di Vihara Dharma Mulya Kabupaten Kulonprogo
Authors: Tugiman Tugiman Tugiman , Dewi Mei Sucita , Dhamayanti Puri , Rispatiningsih Dwi Maryani
Published: January 2023

Dari sekian banyak buah-buah yang dipasarkan terdapat limbah kulit pisang yang belum dimanfaatkan secara maksimal. Selain dalam bidang perkebunan, di sekitar vihara Dhamma Mulya banyak juga yang berjualan pisang goreng. tetapi banyak dari umat buddha di sekitar vihara yang masih belum bisa memanfaatkan limbah buah pisang untuk dijadikan sebuah cemilan yang nantinya akan bernilai jual tinggi. Berdasarkan kondisi tersebut tim bertujuan memberikan pengetahuan dan pelatihan keterampilan kepada masyarakat di sekitar vihara dhamma mulya  Kabupaten Kulon Progo untuk mengolah limbah kulit buah pisang menjadi camilan sehat yang dapat meningkatkan perekonomian. Produk ini akan kami beri brand CHIPS KUSANG (Keripik Kulit Pisang) Produk ini akan menjadi camilan sehat dan memiliki nilai jual lebih tinggi. Pendekatan dalam pengabdian kepada masyarakat ini adalah dengan Participatory Action Research (PAR). PAR merupakan pendekatan yang prosesnya bertujuan untuk pembelajaran dalam mengatasi masalah dan pemenuhan kebutuhan praktis masyarakat, serta produksi ilmu pengetahuan, dan proses perubahan sosial keagamaan. Adapun dalam tahapan-tahapan yang akan kami lakukan antara lain: Analisis situasi masyarakat, Menentukan tujuan kerja, Rencana pemecahan masalah, Pendekatan sosial, Pelaksanakan kegiatan dan yang terakhir adalah Evaluasi kegiatan.
Antibacterial Activity of Edible Film with the Addition of Betel Leaf Extract (Piper betle) againts Streptococcus mutans
Authors: Nasution Azlaini Yus , Wardaniati Isna , Lestari Sintia Ayu
Published: January 2023

Edible films are generally used as packaging materials to protect food and can be eaten with the packaged product. In addition, the edible film can be affixed to the tongue, so that it immediately melts in the mouth. Products like this can be added to betel leaf extract which can function as an oral antiseptic, that can inhibit the growth of Streptococcus mutans. The purpose of this study was to obtain the results of the inhibition of edible film added with water extract of betel leaf with concentrations of 30%, 50%, and 70%. The research was conducted through experiments in the laboratory by measuring the diameter of the inhibition zone that occurred. The diameter of the average inhibition zone against Streptococcus mutans produced by edible film added 30%, 50%, and 70% aqueous extract of betel leaf, respectively, was 14.36 mm, 18.17 mm, and 24.74 mm. An edible film added water extract of betel leaf can inhibit Streptococcus mutans.
Evaluation of Toothpaste Preparations Containing Propolis Ethanol Extract
Authors: Wardaniati Isna , Indriastuty Danty
Published: January 2023

ABSTRACT

The Trigona bee is a native Asian bee that does not have a stinger and produces propolis. Propolis is useful as an antioxidant, antimicrobial, anti-inflammatory, and antiviral. This study aims to evaluate the preparation of toothpaste which is added from propolis ethanol extract. Extraction was carried out by maceration method using 96% ethanol. Toothpaste obtained was made in four formulas based on differences in concentration, evaluation of preparation, organoleptic, homogeneity, pH test, viscosity test, foam height test and preference were carried out. Data were analyzed descriptively. The preparation of propolis ethanol extract toothpaste with various concentrations of propolis extract showed organoleptic test results in the form of a light brown color, soft texture, distinctive smell of propolis, fresh taste typical of propolis, and homogeneous, preference test of four formulas, 50% chose ordinary from 5 options. Based on each evaluation test of the paste from the preparation of propolis ethanol extract that has been made, all of them meet the criteria and requirements for physical evaluation according to SNI toothpaste No. 12-352-1995.
Comparison of the Aedes spp Eggs Number Trapped in Ovitrap Using Rainwater and Municipal Water
Authors: Daswito Rinaldi , Ronaldo Ronaldo , Kurnia Risman , Aziz Alkausyari
Published: January 2023

Dengue Hemorrhagic Fever (DHF) is still a public health problem in Indonesia. The number of sufferers and the area of their distribution is increasing along with the increasing mobility and population density. The purpose of this study was to compare the number of eggs trapped in the ovitrap using rainwater and PDAM water. This type of research was a quasi-experimental design with a post-test-only design. Determination of the sampling location was done by determining the point of the house of DHF sufferers and their surroundings. The total number of eggs trapped in the ovitrap was 3829 eggs. The number of rainwater ovitraps (2279) traps more Aedes spp mosquito eggs than PDAM water ovitraps (1553). Ovitrap index of 61% in this study was included in the level 4 category or high above 40%. The results of the Mann-Whitney analysis with p-value = 0.637 > 0.05 means that it did not showed a significant difference between the number of eggs trapped in the rainwater ovitrap and PDAM water. There was no difference in the average number of eggs in rainwater and PDAM water ovitrap media. The community of RT 2 and RT 3 RW 1 are expected to always carry out the Mosquito Nest Eradication (PSN) movement at least once a week to reduce the proliferation of the DHF vector.
Collaborating the Role of Stakeholders in Waste Management on Penyengat Island, Riau Islands Province, Indonesia
Authors: Ikhwan Zainul
Published: January 2023

The main problem of waste management on small islands is that the amount of waste often exceeds the capacity that the island can handle, due to the limited availability of land, volume of land, budget, and human resources. Unmanaged waste generation has an ecological impact such as environmental pollution, loss of natural resources; economic impacts such as decreased productivity; social impacts such as the emergence of conflict, and health impacts uch as increasing the number of environmental-based diseases on the community and the wider environment. The stakeholder role collaboration strategy is needed. This study aims to formulate a collaborative strategy for the role of stakeholders in the proper management of Penyengat Island, Tanjungpinang City. This research method is qualitative. Waste management on the island of Penyengat demands the role of the government, the private sector, and the community. The government moves in terms of regulations, facilities, and implementers. The role of the private sector is more to provide funds and empowerment. While the role of the community is more on empowering efforts to reduce waste and its utilization.
Planning in the Management System
Authors: Sergo Rukhadze Sergo Rukhadze
Published: January 2023

Planning determines the development perspective of manufacturing system as an object and subject of the management, active managerial impact over the management system, by means of which the determination of whole manufacturing system`s development forms is implemented to reach the goal set.
The planning relies on the following principles: scientific character, complexity, balance calculation, projecting, multiple variants of decisions, adjustment of optimal variant, normativity, formation of reserves in order to decrease the manufacturing risks, approval of quantitative and qualitative indicators of the program, mandatory character of fulfilment and personification for fulfilment of the plan.
Since the creation and development of the plan, it is beneficial to analyze its model from the position of practice, we may imagine the possible condition and see if how much it is foreseen and how the plan works under such conditions. Then it is necessary to put the plan in action, control its realization process, implement corrections in it (in case of necessity).
Keywords: planning, manufacture, decision, resolution, organization, strategy, tactics, resources.