bluuebunny/crossref_metadata_2025 huggingface dataset:
Lipids Fortified Nano Phytopharmaceuticals: A Breakthrough Approach in Delivering Bio-actives for Improved Therapeutic Efficacy
Authors: Shah Sunny , Chauhan Harshida , Madhu Hardik , Mori Dhaval , Soniwala Moinuddin , Singh Sudarshan , Prajapati Bhupendra
Published: January 2024

Phytopharmaceuticals, derived from natural sources, manifest tremendous potential for
therapeutic applications. Nevertheless, effective delivery of these bio-actives presents significant
challenges. A breakthrough in fortifying phytopharmaceuticals within phosphatidylcholine is a
promising remedy to overcome solubility, permeability, and other related drawbacks. This intrinsic
lipid, which is obtained from both natural and synthetic sources, confers numerous benefits, encompassing
heightened solubility, augmented bioavailability, and enhanced stability. The conjugation of
phytopharmaceuticals with phosphatidylcholine enables improved dermal permeation, absorption,
targeted distribution, and the possibility of synergistic results, eventually improving therapeutic efficacy.
Additionally, the use of phytopharmaceuticals enriched with phosphatidylcholine presents a
promising route for overcoming the limitations imposed by conventional delivery techniques, encouraging
more effective treatments. The review provides a thorough analysis of phosphatidylcholine-
incorporated phytopharmaceuticals as nanomedicine with variables that significantly affect their
therapeutic efficacy. Moreover, the review elaborates on how phosphatidylcholine improves solubility,
permeability, and tissue distribution and boosts the potential of phytopharmaceuticals. Further,
the review underscores the significance of nano-formulation strategies, analytical methodologies, and
forthcoming prospects to propel this field forward. Furthermore, the review emphasizes the potential
inherent in this innovative approach while highlighting the importance of additional research endeavors
and collaborative initiatives to unlock the therapeutic benefits of phosphatidylcholinefortified
phytopharmaceuticals, enhancing patient well-being.
Nanoparticles as Catalysts: Exploring Potential Applications
Authors: Basu Shibani , Banik Bimal Krishna
Published: January 2024

:

Nanoparticles have emerged as highly promising catalysts due to their unique physical
and chemical properties arising from their small size and high surface area–to–volume ratio. This
review delves into the diverse applications of nanoparticles as catalysts in various chemical reactions.
A key advantage lies in their substantial surface area–to–volume ratio, facilitation, enhanced
accessibility of reactants, and heightened interaction with the catalyst surface. This distinctive characteristic
results in improved catalytic activity and efficiency. Additionally, size-dependent properties,
such as surface plasmon resonance and quantum confinement effects, offer opportunities for
tailoring catalytic behavior. Despite their immense potential, challenges such as synthesis, stability,
toxicity, aggregation, and recyclability require attention. Future research should prioritize scalable
and sustainable synthesis methods, improve catalyst stability under harsh conditions, and ensure
safe handling and disposal. This review provides an overview of the role of nanoparticles as catalysts
and highlights their significance in various fields, highlighting their exceptional performance,
versatility, and environmental benefits.
Differentiation of Restless Genital Syndrome from Persistent Genital Arousal Disorder: A Case Report
Authors: Haghshenas Mandana , Poor Elham Moein
Published: January 2024

Objective:

Persistent genital arousal disorder (PGAD) presents with a constant
unwelcome sensation of genital arousal. Moreover, restless genital syndrome (RGS) is one
of the restless leg syndrome (RLS) variants

Case Representation:

We aimed to clarify the differences between clinical diagnoses of
these two similar conditions. Assessing the circadian pattern of symptoms, the simultaneous
presence of RLS and restless bladder syndrome, exacerbation of symptoms with caffeine
use, healing with magnesium use, and familial history of RLS helped us with the
differentiation between PGAD and RGS.

Conclusion:

We propose to rule out the diagnosis of RGS in all patients with PGAD
symptoms.
The Effects of Standard Pharmacotherapy on Oxidative Stress Markers in Bipolar Patients: A Systematic Review
Authors: Rahsepar Sara , Karizaki Golnaz Abbasi , Samadi Sara , Jomehzadeh Vahid , Sadjadi Seyed Alireza , Mohammadpour Amir Hooshang , Arasteh Omid , Johnston Thomas P. , Sahebkar Amirhossein
Published: January 2024

Background:

Bipolar disorder is a complex mental disorder with a multifactorial
pathology. Meta-analyses have shown that bipolar disorder is associated with imbalanced
oxidative status, which can contribute to disease progression. Therefore, restoring
the oxidative imbalance could be beneficial in the treatment of bipolar disorder. The firstline
pharmacotherapy for bipolar disorder is lithium, anticonvulsants (particularly sodium
valproate), and atypical antipsychotics. In the present review, we sought to describe the
effects of these first-line medications on oxidative stress in bipolar patients.

Methods:

We systematically searched databases through January 2022, including the Web
of Science, PubMed, Scopus, and Embase, with no language or time restrictions. Eligible
articles that assessed oxidative markers in bipolar patients following standard pharmacotherapy
were included.

Result:

According to Newcastle Ottawa and NIH scales, the overall quality of the included
articles was low, and their heterogeneity prevented us from performing a meta-analysis.

Conclusion:

We found that standard medications, especially lithium, can potentially alleviate
oxidative imbalance based on a reduction in oxidative markers, such as TBARs and
MDA, although randomized clinical trials are needed to unequivocally confirm these results.
ORTAOKUL 8.SINIF ÖĞRENCİLERİNİN TAM SAYILARDA TAM SAYI KUVVETİ DEĞERLERİNİN HESAPLANMASINDAKİ KAVRAM YANILGILARININ BELİRLENMESİ
Authors: Yenen Emin Tamer , Turhal Tekmile
Published: January 2024

Bu araştırmanın amacı ortaokul 8.sınıf öğrencilerinin tam sayılarda tam sayı kuvveti değerlerinin hesaplanmasındaki kavram yanılgılarının belirlenmesidir. Bu çalışma nitel araştırma yöntemi çerçevesinde desenlenmiştir. Araştırmanın çalışma grubunu 2021-2022 eğitim öğretim yılında Nevşehir il merkezinde öğrenim gören 70 tane 8.sınıf öğrencisi oluşturmaktadır. Araştırmanın verileri araştırmacıların hazırladığı Tam Sayıların Tam Sayı Kuvveti Değerlerinin Hesaplanması Testi’nin öğrencilere uygulanması ile toplanmıştır. Testin soruları hazırlanırken alan uzmanlarının görüşleri dikkate alınarak benzer üslü ifadelerin değerlerinin hesaplanması sorulmuştur. Böylece öğrencilerin hatalı cevapları ve kavram yanılgısı olan cevapları ayırt edilmiştir. Verilerin analizinde içerik analizi tekniği kullanılmıştır. Cevaplar ayrıntılı bir şekilde incelenerek ne tür kavram yanılgılarının oluştuğu gösterilmiştir. Çalışma sonucunda öğrencilerin üslü ifadenin değerini hesaplamada, sıfırıncı kuvvetin değerinin hesaplanmasında, tabanın veya kuvvetin negatif olduğu durumlarda çeşitli kavram yanılgılarına sahip oldukları görülmüştür. Araştırma sonuçlarına dayanarak öğretmenlere örnekler çözülürken görülmesi muhtemel kavram yanılgılarının üzerinde durmaları ve neden doğru olmadıklarını dayanaklarıyla açıklamaları önerilebilir.
Análisis de redes y modelado de micronegocios basado en agentes
Authors:   Universidad Nacional Autónoma de Honduras UNAH, Andino-González Patricia , Acosta-Tzin Jose Valdo ,   Universidad Nacional Autónoma de Honduras UNAH, Raudales-García Elí Vicente ,   Universidad Nacional Autónoma de Honduras UNAH, Aguilar-Hernández Pablo Alcides ,   Universidad Nacional Autónoma de Honduras UNAH
Published: January 2024

Introducción: El análisis de las estructuras de las redes sociales y modelos de simulación basados en agentes permiten conocer y analizar el comportamiento de los diferentes actores que interactúan dentro de un sistema. Objetivo: es realizar un análisis de redes y modelado de micronegocios basados en agentes para conocer, identificar y comparar las relaciones existentes y el comportamiento entre los actores, proveedores, acreedores, instituciones públicas y privadas de los micronegocios del rubro de abarrotería en el distrito central de Honduras a través de un modelo de simulación. Metodología: Este estudio de alcance local fue realizado con una naturaleza descriptiva, bajo el enfoque mixto donde se recolectaron datos a través de entrevistas con gerentes de los micronegocios que representan la totalidad de la población de la unidad de estudio. Resultados: En la elaboración de los sistemas de redes se empleó el software Pajek y para el desarrollo del modelo de simulación se utilizó NetLogo. Conclusiones: la centralidad y densidad de los actores de una red junto con el modelado a través de la simulación, permite conocer las aproximaciones y comportamiento de los agentes que garantizan la sostenibilidad y productividad de los micronegocios.
Improving writing skills of expository text with ‘think, talk, write’ learning method
Authors: Budiyono Sri , Sukini Sukini , Warsihno Joko , Sutaji Sutaji , Amertawingrum Indiyah Prana
Published: January 2024

This studi was aimed at describing the learning process of writing expository texts in class VII C SMP Ekakapti Karangmojo Gunungkidul, through the use of the TTW learning method. and describing the results of writing an exposition text for class VII C SMP Ekakapti Karangmojo Gunungkidul using the TTW learning method. This research is a Classroom Action Research (CAR). The technique of analyzing the data is using quantitative and qualitative techniques. Based on the results of the study, the conclusions that can be drawn are as follows. First, their exposition text writing skills have improved after using the TTW learning method. The improvement in writing exposition text skills was known from the pre-cycle, first cycle, and second cycle tests. The average score of their pre-cycle was 58.67. This result belongs to the poor category. Furthermore, for the average score in the first cycle the result was 75.63 so that it can be said to have increased and is included in the good category. Thus, there was an increase of 16.96% from the pre-cycle. In the second cycle, the average score achieved was 82.61. This result is included in the good category as well. Thus, there was an increase from the first cycle of 6.98% and 23.94% of the pre-cycle results. Second, learning to write Exposition texts through the TTW learning method has been proven to be able to change students’ negative attitudes and behaviors into positive ones. These changes can make students who are less enthusiastic and less active become more alert, excited, happy, and able to enjoy learning. Students become more active in thinking (think), actively discussing (talk), and more actively writing exposition texts (write).
Improving Students’ Writing Skills of Content and Context Aspect in Biology using Guided Inquiry Learning
Authors: Fitri Annisa , Widoretno Sri , Saputra Alanindra
Published: January 2024

This research aimed to improve student writing skills in biology learning. The subjects of this research were 28 students in senior high school. This research was classroom action research carried out for 3 cycles. Each cycle consists of planning, implementation and observation, also reflection. Research instruments were assessment sheets containing the aspects of writing content and context-based on writing skills rubric assessment adapted from Mclean and Wyse (2012). The research procedure were carried out by taking action based on the results of the evaluation of each cycle which forms the basis for improvement in the next cycle. Writing skills data was validated using triangulation techniques: observation, interviews, and documentation. Data analysis used qualitative descriptive. The results showed that the scores for the quality of the content and the context of the students' writing in the pre-cycle were at scores of 2, 3, and 4 with an average of 42% for the quality of the content and 53% for the quality of the writing context, all at level 1. Improvement in scores and the average percentage occurs in cycles I, II, and III which occurs linearly according to the increase in the quality score of the problem formulation, the summary of the results of collecting and processing information, as well as the results of discussions and conclusions, thus the application of the Guided inquiry learning model improves students' writing skills in learning biology.
Development application Smartness Help for the disabled blind with text and image detection
Authors: Putri Anggi Erlina , Azizah Nur , Jannah Irradhiatul
Published: January 2024

Blindness is a condition in which a person’s sense of sight does not function either partially (low vision) or as a whole (total blindness). Physical limitations make it difficult for them to access information and knowledge in the form of books or other printed media. This study was aimed at developing application smartness help for the disabled blind with text and image. The research method (RD) uses the waterfall model. The study was conducted at SLB-A YPPLB Payakumbuh with the results of the assessment of material experts 93.3%, and media experts 86.7% who stated that the Smartness Help application was “very feasible” to use and be tested on blind people. The results of trials on blind people using the Smartness Help application yielded 87% results, all of which were categorized as very feasible.
Enhancing social sciences learning effectiveness with a learning management system
Authors: Budiman Budiman , Supardi Supardi , Sudrajat Sudrajat
Published: January 2024

This study aims to analyze the use of Learning Management System (LMS) in improving the effectiveness of Social Science (IPS) learning. This research uses the research method of literature study, which involves searching, selecting, and analyzing literature relevant to the research topic. The results of the analysis show that the use of Learning Management System (LMS) in social studies learning has great potential to improve learning effectiveness. LMS provides accessibility and flexibility that allows students to access learning materials anytime and anywhere, overcoming space and time constraints. The interactive and collaborative features in the LMS facilitate interaction and collaboration between students and teachers, so students can share ideas, understanding, and experiences with fellow students and teachers. Through the LMS, teachers can monitor student progress in real-time and provide prompt feedback, which helps in the evaluation of learning. This research provides valuable insights for education practitioners in harnessing the potential of LMS to improve social studies learning.
Comparison Metaphor and Reasoning Comprehension Between Children with Borderline Intelligence and Typical Developing School-Aged children
Authors: Lee Eun Kyoung , Choi Seong Hee , Ko Yoo Kyeong
Published: January 2024

Purpose: Metalinguistic skills play a critical role in school-aged children’s language development and academic achievement. This study investigates whether metaphorical reasoning in children with borderline intellectual functioning (BIF) (or slow learners) differs from that of typically developing children.Methods: A total of 52 children (29 boys and 23 girls), who voluntarily agreed to participate in the study, were included. Children were categorized into three groups (15 slow learner group, 18 chronological age-matched group, and 19 language age-matched group) based on their K-WISC and receptive vocabulary scores in the Receptive and Expressive Vocabulary Test (REVT). All children completed the Metaphorical and Reasoning Comprehension test (MARC) to estimate their metaphor and reasoning comprehension ability.Results: As a result of a one-way analysis of variance, there was a significant difference among the groups, and a significant difference was found between the slow learners and the chronological age-matched group (p=0.000), but no significant difference was presented between the slow learner group and the language age-matched group. Similarly, regarding the expressive vocabulary score, a one-way ANOVA revealed a significant difference only between the slow learner and the chronological age-matched group (p=0.000). When comparing the scores for metaphorical reasoning comprehension among the three groups, the metaphorical reasoning comprehension scores were significantly different among the groups, with the slow learners having the lowest scores: the slow learner group was substantially different from the language age-matched group (p=0.025), while there was also a significant difference between the slow learner group and the chronological age-matched group (p=0.000).Conclusions: This study suggests that the semantic component of language is not affected in BIF children, but rather, the meaning of words is affected by tasks that require higher-order metalinguistic skills, such as understanding metaphorical inferences embedded in the context of a sentence. Accordingly, the ability to understand metaphorical reasoning can identify slow learners.
Selection of a Neural Network Architecture for Implementation of Cognitive Functions of Network Software for Control of a Group of Interacting Small Space Vehicles
Authors: Shilenkov E. A. , Frolov S. N. , Titenko E. A. , Miroshnichenko S. Y.
Published: January 2024

The purpose of the research is to substantiate and select the architecture of a neural network for the possibility of implementing the cognitive functions of network software for controlling a grouping of interacting small spacecraft.

Methods are based on the concepts of AI theory for managing the grouping of small spacecraft - the use of adaptive methods and tools that allow making decisions, similar to the mechanisms of human thinking. With regard to space communication systems with a heterogeneous structure, AI methods and technologies are aimed at the processes of predicting the state in communication channels between network nodes and automatic reconfiguration of the network of devices based on the learning processes of a neural network (NN).

Results. In the learning and forecasting mode, it is necessary to use time series of parameters and coordinates of specific pairs of small spacecraft with non-zero line of sight. Especially for time series analysis, recurrent neural networks (RNN) are used, in particular, LSTM. The idea of RNN operation is to use as input data for the current forecast not only the state vectors of the SVs and their coordinates, but also the previous value of the communication quality, actual or predictive. The paper shows that the onboard computing power of a separate MSC does not allow performing forecasting and training on board. Therefore, a dedicated ground segment of forecasting and monitoring is required, which will collect a posteriori information, periodically train the cognitive model, use it to predict the quality of communication, and transmit the results to the network nodes to build data transmission routes.

Conclusion. The analysis of modern solutions and the choice of neural network architecture for the implementation of the cognitive functions of the network software for controlling the grouping of interacting small spacecraft showed that the neural networks of the Transformer architecture, which are based on the mechanism of internal attention, most fully meet the requirements of the project. The Transformer architecture allows using the entirety of a priori data, has a high learning and forecasting speed.
Content Validity and Psychometric Properties of the German Version of the Holm and Cordoba Urinary Tract Infection Score for Uncomplicated Urinary Tract Infections in Women: Protocol for a Validation Study
Authors: Piontek Katharina , Nestler Sophie , Holm Anne , Brodersen John Brandt , Apfelbacher Christian
Published: January 2024

Background

Uncomplicated urinary tract infections (UTIs) in women are among the most common bacterial infections in primary care. Given the health threats related to the overuse of antibiotics, alternative options are of increasing importance. Patient-reported outcome measures are valuable tools for including the patients’ perspective when evaluating the efficacy of these strategies. Aiming to identify a suitable instrument to measure the severity and bothersomeness of UTI symptoms in women, we performed a systematic review of the literature and identified the Holm and Cordoba Urinary Tract Infection Score (HCUTI), which measures the severity, bothersomeness, and impact of uncomplicated UTIs on daily activities. This instrument showed sufficient content validity but needs translation and further validation before it can be used in German research.

Objective

For use in the German setting, we aim (1) to perform translation and linguistic validation of the HCUTI and (2) to evaluate content validity and psychometric properties of the German version of the HCUTI in a population of women with uncomplicated UTIs.

Methods

The HCUTI will be translated and linguistically validated using the dual-panel method. This process involves a bilingual translation panel and a lay panel to check the comprehensibility of the translation. Content validity of the translated questionnaire will be assessed using cognitive interviews according to the criteria for good content validity as recommended by the COSMIN (Consensus-based Standards for the selection of health Measurement Instruments) group involving women with uncomplicated UTIs and health care professionals. Subsequent psychometric validation of the German version of the HCUTI in a population of women with uncomplicated UTIs will include the assessment of structural validity, internal consistency, test-retest reliability, construct validity, responsiveness, and interpretability.

Results

Results of the translation and linguistic validation process and the results of the content validity study were obtained in September 2023 and will be published separately. Data on the psychometric properties of the German version of the HCUTI are anticipated in mid-2024.

Conclusions

We expect that data from the content validity study will provide important suggestions for potential modifications of the HCUTI for use in the German setting. The final version of the questionnaire will be used for the assessment of its psychometric properties in a large population of women with uncomplicated UTIs.

International Registered Report Identifier (IRRID)

PRR1-10.2196/49903
Correction: Social Media Use and Its Concurrent and Subsequent Relation to a Biological Marker of Inflammation: Short-Term Longitudinal Study (Preprint)
Authors: Lee David , Jiang Tao , Crocker Jennifer , Way Baldwin
Published: January 2024

UNSTRUCTURED

REMOVE
The Effect of the Covid-19 Pandemic on Mental Health: Quasi-Experimental Evidence from Indonesia
Authors: Sahadewo Gumilang , Hendra Permana Yudistira , Gu Yuanyuan , Schroeder Elizabeth-Ann
Published: January 2024

Introduction/Main Objectives: This research aims to explore and analyze the effect of the COVID-19 pandemic on mental health status as measured by DASS-21. Background Problems: The prolonged impact of the COVID-19 pandemic on the global economy may have adversely affected mental health. A decrease in income and consumption and the uncertainties surrounding job security and business performance have been some of the main factors contributing to mental health issues. Novelty: This paper aims to evaluate the effect of the COVID-19 pandemic—as a natural experiment—on mental health measured by DASS-21 and how the effect of the pandemic varied across different socioeconomic subgroups. Research Methods: We conducted an online survey across Indonesia to collect self-reported mental health status and socioeconomic characteristics before and during the COVID-19 pandemic to measure its impacts on mental health. Finding/Results: Our results suggest that the COVID-19 pandemic has had an adverse impact on mental health, particularly in terms of anxiety and stress. The effect has been higher among individuals with lower self-efficacy, lower expenditure, and lower education levels. Conclusion: The health and economic crisis driven by the COVID-19 pandemic affected individuals' mental health, suggesting the need for appropriate policy responses.
Sotagliflozin and Kidney Outcomes, Kidney Function, and Albuminuria in Type 2 Diabetes and CKD
Authors: Sridhar Vikas S. , Bhatt Deepak L. , Odutayo Ayodele , Szarek Michael , Davies Michael J. , Banks Phillip , Pitt Bertram , Steg Ph. Gabriel , Cherney David Z.I.
Published: January 2024

Background

In the initial analysis of the Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED) trial, because of early trial termination and suspension of adjudication, reconciliation of eGFR laboratory data and case report forms had not been completed. This resulted in a small number of kidney composite events and a nominal effect of sotagliflozin versus placebo on this outcome. This exploratory analysis uses laboratory eGFR data, regardless of case report form completion, to assess the effects of sotagliflozin on the predefined kidney composite end point in the SCORED trial and additional cardiorenal composite end points.

Methods

SCORED was a multicenter, randomized trial evaluating cardiorenal outcomes with sotagliflozin versus placebo in 10,584 patients with type 2 diabetes and CKD. This exploratory analysis used laboratory data to derive the eGFR components and case report form data for the non-laboratory–defined components that together made up the kidney and cardiorenal composites. AKI was also assessed in this dataset.

Results

Using laboratory data, 223 events were identified, and sotagliflozin reduced the risk of the composite of first event of sustained ≥50% decline in eGFR, eGFR <15 ml/min per 1.73 m2, dialysis, or kidney transplant with 87 events (1.6%) in the sotagliflozin group and 136 events (2.6%) in the placebo group (hazard ratio [95% confidence interval], 0.62 [0.48 to 0.82]), P < 0.001). Sotagliflozin reduced the risk of a cardiorenal composite end point defined as the abovementioned composite plus cardiovascular or kidney death with 239 events (4.5%) in the sotagliflozin group and 306 events (5.7%) in the placebo group (hazard ratio [95% confidence interval], 0.77 [0.65 to 0.91], P = 0.0023). The results were consistent when using different eGFR decline thresholds and when only including kidney death in composites (all P < 0.01). The incidence of AKI was similar between treatment groups.

Conclusions

In this exploratory analysis using the complete laboratory dataset, sotagliflozin reduced the risk of kidney and cardiorenal composite end points in patients with type 2 diabetes and CKD.

Clinical Trial registry name and registration number:

ClinicalTrials.gov Identifier: NCT03315143.
The Use of Artificial Intelligence in Various Fields
Authors: Tandalaskar Snigdha , Roy Deb Prakash , Ghosh Mrinal Kanti , Dey Ishika
Published: January 2024

Abstract: Intelligent machines will ultimately substitute or improve on human abilities in many fields. Artificial intelligence is the intelligence displayed by software or robots. It falls within the umbrella of computer science. As it has improved human lives in many ways, artificial intelligence is growing in popularity as a subject of study in computer science. Over the past two decades, artificial intelligence has significantly boosted performance across a variety of industries, including manufacturing, services, and education. Artificial intelligence research has given rise to the fast-expanding field of expertise system. Artificial intelligence applications have a significant impact on many aspects of life because expert systems are frequently employed nowadays to handle complicated problems in domains like education, engineering, business, medical, weather forecasting, etc. The quality and efficiency have increased in the fields using artificial intelligence technologies. This paper provides an overview of this technology and the application of artificial intelligence in various fields, paying particular attention to how this technology is used in the field of education and discussing its significance, search methods, inventions, and future.
Reimagining Gender: Exploring Feminist Consciousness in Shashi Deshpande\'s Literary Landscapes – A Comparative Study of Three Novels
Authors: Lata Suman
Published: January 2024

Abstract: Shashi Deshpande, an eminent Indian author, has contributed significantly to contemporary Indian literature, particularly through her exploration of gender and feminism. This research paper aims to delve into Deshpande's literary landscapes by analyzing three of her prominent novels: "Roots and Shadows," "That Long Silence" and "Dark Holds No Terrors" The study focuses on uncovering the intricate portrayal of feminist consciousness in Deshpande's works and examining how her characters challenge traditional gender roles, negotiate societal expectations, and seek personal liberation. By employing feminist literary theory and employing textual analysis, this paper aims to shed light on the themes of identity, autonomy, patriarchy, and the complexities of women's lives in Deshpande's novels.
Monitoring of food handlers and their influence on the preparation of ready-to-eat foods
Authors: Ochoa-Agudelo Susana , Tobón-Ospina Juliana , Fuentes-Vanegas Mayra Alejandra , Durango-Zuleta Mónica María
Published: January 2024

Introduction: Transmission of foodborne pathogens is related to inadequate sanitary conditions, which are derived from either the food preparation process or the person who prepares it. Food handlers are essential to preserve food innocuousness and protect consumer’s health. Objective: To evaluate demographic characteristics, hygiene practices, knowledge, work conditions and the presence of pathogenic microorganisms in food handlers at public school restaurants in Antioquia, Colombia. Materials and methods: The study evaluated 104 food handlers in a municipality in Antioquia. Demographic data and stool samples were collected to identify intestinal parasites, Salmonella spp., and Staphylococcus aureus. Results: The presence of intestinal parasites (e.g. Entamoeba Complex and Trichuris trichiura) was identified in 61% of female participants. Staphylococcus aureus was isolated from 49% of food handlers. Conclusion: Infection of food handler was confirmed, making them potential sources of food contamination. They are committed to their work and have the knowledge to preserve basic hygiene conditions. It is highlighted their importance and influence in adequate hygienic practices to minimize the risks of transmission, as well as the need for medical treatment and regular checkups of food handlers to counteract the risk to consumers.
Efficiency and safety of combined herbicide Avrora, OD for corn protection
Authors: Bereznov Aleksey V. , Astarkhanov Ibragim R. , Ashurbekova Tamila N. , Behzad Abdulla
Published: January 2024

Field small-plot experiments were carried out in the Moscow region, Rostov region and the Republic of Dagestan in 2021-2022. Herbicide Avrora, OD (100 g/l mesotrione + 80 g/l amicarbazone + 60 g/l nicosulfuron + 5 g/l aminopyralid) was studied during the two growing seasons. The high biological efficiency of Avrora, OD at the stage of 3-6 leaves of corn and the early growth stages of weeds was established. The optimal herbicide rates, the timing of protective measures, and the sensitivity of certain types of weeds were determined depending on the type of weed in crops to combat annual and perennial weeds. The increased application rate of the tested herbicide up to 1.0 l/ha led to an increase in the effectiveness of the pesticide in the number and weight of weeds and was 92.497.9 and 92.497.8 %, respectively. By the harvesting time, infestation of corn crops in the control decreased to 1617 plants/m2. In the variants with herbicides, infestation of crops did not exceed 8 plants/m2. High yields of green mass in the first zone and corn grains in the second and third soil-climatic zones were noted in all tested experimental variants. The use of Avrora herbicide in the early phases of weed growth on vegetative corn plants does not have a negative effect on crop plants and contributes to yield increases of up to 53.756.2 % when cultivating grain corn and up to 138.5 % when cultivating green mass corn.
Evaluation of different lines of vegetable soybean Glycine max L. Merr. under conditions of the Moscow region
Authors: Mullo Panoluisa Freddy E. , Semenova Natalia A. , Romanova Elena V.
Published: January 2024

Edamame is a special soybean ( Glycine max (L.) Merr .) harvested as a vegetable when the seeds are immature (R6 and R7 stage) and have expanded to fill 80 to 90 percent of the pod width. The study was conducted in the experimental field of Federal Scientific Vegetable Center in the Moscow Region in 2020-2022 and Agro-biotechnological department, Agrarian and Technological Institute, RUDN University. The object of research was 3 accessions of soybean ( Glycine max L.): accession A, accession F, Hidaka and Lira. Before sowing, soybean seeds were inoculated with Optimays 400 ( Bradyrhizobium japonicum ) and Biobesta ( Sinorhizobium fredii ). In the field experiment, 10 soybean samples were taken from each plot at the stage of biological ripeness to determine plant height (cm), number of pods per plant, number of stems per plant, stem width (mm), average number of seeds per plant, weight of 1000 seeds (g) and yield (t/ha). The experiment was designed in a complete random block with a factorial arrangement. Thus, we had 4 accessions and 3 treatments (C - control, V1 - Bradyrhizobium japonicum and V2 - Sinorhizobium fredii ) with 3 replacations. The study showed that accession A had the highest average yield per hectare (2.70 t/ha) and weight of 1000 seeds (159 g). Under conditions of the Moscow region, variant V2 ( Sinorhizobium fredii ) had the highest average yield (2.57 t/ha) and weight of 1000 seeds (100.25 g). Therefore, more than 90 % of the results obtained for these two indicators are associated with the use of V2 treatment. For the rest of the studied indicators, no significant differences were found, and they did not affect the efficiency indicators. The combination of accession A and treatment V2 led to the highest average yield (2.99 t/ha). The product based on Sinorhizobium fredii showed the best indicators for all the studied samples.
Estimating information volume change in hexagonal descrete global grid systems with aperture 7
Authors: Shurygina A.A. , Samsonov T.E.
Published: January 2024

The authors analyze the change in the amount of information at each level of hexagonal discrete global grid systems with an aperture of 7. They provide mechanisms for sampling spatial data and changing their granularity through hierarchical transitions between levels. The resolution is related to the volume of spatial data that can be displayed with the current grid. Three metrics are used to estimate the parameter having quantitative findings on the built-up areas and qualitative land use-and-cover data as an example. The results showed that the amount of information decreases non-linearly with increasing grid cell size; the nature of the change differs for different data types and aggregation methods. The study led to the conclusion that it is possible to predict the number of levels within which the information content reduces insignificantly with a cutback in detail for a specific DGGS configuration and data type
Interpretation and Proof burden of the Regulation for Authenticity presumption of Private documents
Authors:   Wonkwang University Legal Research Institute has, Kim Il Ryong
Published: January 2024

Article 357 of the Civil Procedure Act stipulates that in order for a document to be subject to documentation in civil proceedings, its authenticity must be proved. On the other hand, Article 358 of the Civil Procedure Act provides a provision for presuming the authenticity of the entire document if it is a document signed, sealed, or handprint by the principal or agent.
The precedent established a two-stage presumptive law that if the document contains the seal of the title holder, it is presumed that the title holder was stamped, and thus the entire document was written by the will of the title holder. The former presumption is called the step 1 presumption, and the latter presumption is called the step 2 presumption.
If the two-stage presumptive above is abused, the victory or defeat may be reversed by being used as evidence even though it is an inauthentic document. This should not be tolerated as it runs counter to the ideals of adequacy and fairness in civil litigation.
Therefore, It is a question of how to understand the nature of each presumption around the legal principles of this presumption of private documents under the Civil Procedure Act, and whether the proof burden is shifted to those who want to reverse the presumption due to the presumption.
Based on this point of view, this paper examined the history and interpretation of the presumption theory in the step 1, and the process of enacting presumption regulation in Germany and Japan, Acceptance of the Civil Procedure Act of Korea, Appearance of precedent and its process of change. Then, we reviewed the current status of our precedents and theories and critically reviewed the position of precedents on the strength of the step 1 presumption.
Regarding the step 2 presumption, After confirming that the theory of interpretation in Germany is affecting Korea through Japan, The positions of precedents were closely analyzed to confirm that they were contradictory or ambiguous to each other.
Combining the above review, it is argued that the step 1 presumption should be returned to pure de facto presumption as the most desirable interpretive theory in the current situation, The step 2 presumption is understood as a legal presumption, but considering the interpretation of our regulations and precedents different from Germany, it was concluded that it was reasonable to interpret it as possible to subvert it as counterevidence without changing the proof burden.
Alteration of the existing Law and Validity of Law
Authors:   Wonkwang University Legal Research Institute has, KIM Hyekyung
Published: January 2024

If it is a natural request of criminal justice for the sentence to apply the law with a light sentence for defendant, Article 1, Paragraph 2 of the Criminal Act is only a declarative and cautious provision as in Paragraph 1. As a result, it is the court's duty to apply a more advantageous law to the defendant by comparing the severity of the sentence when there is a change in the law, just as the constitution naturally applies the principle of action even if Article 1 (1) does not exist.
However, in some cases, the law restricts the scope of the time effect of the law, which is called the temporary law. However, since the temporary law is not a request for criminal justice as above, the basic principle that the law with a light sentence for defendant is applied cannot be applied even if there are no special provisions in the criminal law. However, the temporary law also seems to have a change in the state of the law in that the law becomes ineffective at the time limit. For this reason, the Supreme Court did not distinguish between changes in laws and temporary laws.
However, through the Supreme Court's ruling on December 22, 2022, 2020 Do 16420, the Supreme Court clearly distinguished the change of law from the temporary law, and clarified the view that Article 1 (2) of the Criminal Act is subject to “the change of law,” and the temporary law is not applicable. As a result, the previous wrong practice of not distinguishing between the opening and closing of the law and the temporary law has been corrected, but there is still controversy over the temporal effect of the temporary law. In this regard, there are opinions criticizing the recent attitude of the Supreme Court, but if the Supreme Court had judged the effect of the temporary law in the 2020 Do 16420 ruling, it would have to be criticized as “judicial activism.” This is because if the court interprets and engages in even the parts that were not problematic in the case, the judiciary is an active attitude to play the role of the legislature. And this clearly violates the principle of separation of powers.
Nevertheless, in the analysis of the 2020 Do 16420 judgment, it is theoretically reasonable to deal with the temporary law in relation to the application of Article 1 (2) of the Criminal Act. This is because the problem of the temporal effect of the law due to changes in the law includes the temporary law. Therefore, first of all, the Supreme Court's attitude to the target judgment is analyzed, and after distinguishing the difference between the change of the law and the expiration of the law's effect, the criminal interpretation of temporary law is analyzed.
AS TRADUÇÕES DO CONCEITO DE SAÚDE NOS PROCESSOS DE APRENDIZAGEM E AS ESCRILEITURAS NA FORMAÇÃO EM SAÚDE
Authors: Souza Larissa Cavalcante de , Biato Emília Carvalho Leitão
Published: January 2024

No Brasil, a criação do Sistema Único de Saúde (SUS) trouxe o princípio de integralidade e junto com ele a necessidade de que os profissionais percebam a saúde como modos de conduzir a vida. Visando a formação mais efetiva desses profissionais e a diversificação de cenários de ensino e aprendizagem, a leitura e a escritura de textos literários e narrativas vivenciais podem ser um exemplo de atividade provocadora do pensamento e que permita aproximações com experiências e elaborações relacionadas à saúde. O objetivo deste estudo é analisar, a partir de produções textuais de estudantes de Odontologia, os efeitos e o valor da escrileitura na composição do conceito de saúde e no processo formativo na área. O presente artigo realiza essa análise baseado no método da Timpanização, que se fundamenta no pensamento de Derrida e se propõe a lidar com a produção textual em uma via de fuga ao pensamento dualista. Esse método consiste em três gestos: tatear escombros; disseminar sentidos e criar cadeias suplementares. A partir dos textos estudados percebem-se os efeitos e o valor da leitura e da escrita na composição do conceito de saúde e no processo formativo na área da saúde. Desse modo, a inclusão de textos literários e produção escrita em sala de aula – tomados como escrileituras – pode provocar a criação de novos sentidos para conhecimentos e práticas de atenção e educação em saúde.
A AFETIVIDADE E O TRABALHO EDUCATIVO: IMPLICAÇÕES NA CONSTITUIÇÃO DA PERSONALIDADE
Authors: Wyzykowski Tamini , Frison Marli Dallagnol
Published: January 2024

Este estudo tem como principal objetivo investigar algumas implicações das relações afetivas no desenvolvimento do trabalho educativo para a formação da personalidade. A pesquisa é de natureza qualitativa e está configurada na modalidade de Estudo de Caso. A investigação utilizou como instrumentos de produção de dados questionário e entrevista desenvolvidos junto a um grupo de sete professores que trabalham na Educação Básica na rede pública estadual do Rio Grande do Sul (RS). Os dados foram organizados pela Análise Textual Discursiva (ATD) e discutidos com apoio teórico no referencial da Psicologia Histórico-Cultural e da Pedagogia Histórico-Crítica. Na análise foram discutidos resultados relacionados especialmente à categoria afetividade. Os dados sinalizam a relevância das relações afetivas para a aprendizagem e para a formação humana. A afetividade é um elemento significativo do trabalho educativo e implica desenvolvimento da personalidade. O estudo mostra que as relações afetivas precisam ser pensadas a fim de favorecer a formação integral dos estudantes. O trabalho educativo com afetividade requer dos professores um exercício de apropriação de conhecimentos teóricos e práticos e de transformação humana e profissional.
OS DESAFIOS DE ENSINAR CIÊNCIAS NAS COMUNIDADES RIBEIRINHAS: DILEMAS E PERSPECTIVAS DE UM PROFISSIONAL QUE CAMINHA SOZINHO PELAS CURVAS DO RIO
Authors: Dutra José Ricardo Oliveira , Lopes Paulo Tadeu Campos
Published: January 2024

Na região Amazônica a educação é frequentemente desenvolvida em espaços rurais, em muitos casos nas comunidades conhecidas como ribeirinhas. Nesse sentido, os professores dessas escolas precisam constantemente ser ouvidos, a fim de verificar se a realidade das condições dadas para o ensino de ciências estão adequadas. O objetivo deste estudo foi investigar como os professores de ciências dos anos finais do Ensino Fundamental desenvolvem seu trabalho, além de coletar e analisar seus anseios, dificuldades e perspectivas em relação à sua função docente. Os participantes desta pesquisa foram cinco professores de ciências, um licenciado em Ciências Biológicas e quatro pedagogos, da Rede Municipal de Ensino de Manaquiri, Amazonas. Foi aplicado um questionário elaborado com base nos requisitos necessários para a materialização do ensino de ciências. Analisados os dados coletados, verificou-se que os professores de ciências que atuam nessas comunidades, embora devessem atuar como agentes de difusão dos saberes científicos, não conseguem fazê-lo a partir dos parâmetros exigidos e previstos pela normativas legais da educação brasileira. Isso ocorre devido à falta de formação adequada, estrutura física e material insuficientes, falta de apoio da gestão e do Sistema de Ensino, bem como a ausência de processos organizacionais internos que facilitem o planejamento e a execução das aulas. Se faz necessário repensar essas cadeias estratégicas, revendo-as e ajustando-as, tanto pela gestão escolar, quanto pelo Sistema de Ensino. Isso é necessário para que esses professores de ciências possam sentir-se apoiados e, assim, não precisem mais enfrentar sozinhos os desafios da sua profissão.
EM QUE TEMPO ESTAMOS? DESIGUALDADES QUE MARCAM A ESCOLA PÚBLICA BRASILEIRA
Authors: Albert Evelin , Alves Gustavo , Fernandes Maria Beatriz , Souza Renata Cristina Queiroz Rodrigues , Silva Isabelly Vieira da
Published: January 2024

Este artigo, resultado de um estudo realizado na disciplina “Organização e Políticas da Educação no Brasil” no curso de Licenciatura em Ciências Biológicas do Instituto Federal de São Paulo (IFSP), teve por objetivo ler e interpretar os dados atuais sobre a escolarização brasileira. A proposta foi debater os resultados do Censo Escolar de 2021, publicados pelo Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (Inep), e, a partir disso, traçar caminhos possíveis para a escola pública brasileira. Os dados foram analisados com ajuda do software Statistical Package for the Social Sciences. Os resultados apontam que diversas desigualdades marcam a educação brasileira, tornando-a mais distante para a população negra, comunidades com baixa renda e para as mulheres. Faz-se necessário, assim, ampliar as políticas públicas no intuito de aumentar o número de vagas nas escolas, garantir a permanência dos estudantes e atentar-se para a infraestrutura dessas instituições, além de fomentar discussões de gênero, diversidade e desigualdade.