bluuebunny/crossref_metadata_2025 huggingface dataset:
REGULATION OF P53 ACTIVITY BY METHIONINE SULFOXIDE REDUCTASES
Authors: Susuz Yılmaz , Koç Ahmet
Published: December 2023

Aim: p53 is one of the important tumor suppressor proteins in humans and plays a role in many biological functions such as cell cycle arrest, DNA repair, and apoptosis. The aim of this research was to examine the activity of methionine
and the methionine sulfoxide reductase (Msr) enzyme on oxidized p53. Methods: Shuttle vectors that can replicate in both yeast cells and bacterial cells were used in the research. A high copy of the human p53 protein was created
by Gateway cloning technology. Escherichia coli bacteria were used for the plasmid DNA transformation. The isolation experiment was then completed. The accuracy of the process was checked by a run-on experiment in gel electrophoresis.
In addition, the β-Galactosidase assay was performed in the study. Results: Mutants lacking the Methionine Sulfoxide Reductase genes had higher p53-dependent Lac-Z activity compared to the control cells. However, overexpression
of Msr genes did not cause a change in p53 activity. Differences in p53 activity were observed upon treatment of mutants with 1mM hydrogen peroxide. Specifically, cells lacking both the Msra and Msrb genes were found to have less
p53 activity. Conclusions: The loss of activity in p53 in oxidative stress was concluded to be protected against and controlled by the Msr enzymes.
Reflections of The Deterioration in The Ottoman Economy on The Army During Their Last Periods: Backup Applications
Authors: Efe İsmail
Published: December 2023

Yeniçeri Ocağı kaldırılıp yerine yeni kurulacak ordu için çalışmalar yapılırken devletin içinde bulunduğu iktisadi zorluklarda dikkate alınmıştır. Zirai ve ticari faaliyetleri olumsuz yönde etkilemeyecek, hazineye de fazla bir yük
getirmeyecek, ağırlıklı olarak yedeklerden oluşan bir askeri sistem kurulmaya çalışılmıştır. Bu anlayışın bir tezahürü olarak Prusya’daki Landor teşkilatından esinlenerek 1834 yılında, bir yedeklik uygulaması olan redif teşkilatı
kurulmuştur. İlk dönemlerde ordu teşkilatı içinde çok az sayıda olan redif birliklerinin gücü ve ağırlığı zamanla bir hayli artmıştır. Masrafları azaltmak için başvurulan bir başka uygulama ise müstahfızlık olmuştur. 1869’da ordu
teşkilatına giren müstahfızlık hizmeti, rediflik hizmetinin tamamlanmasından sonra ikinci bir yedeklik mükellefiyeti olarak planlanmıştır. Ordunun masraflarını azaltmak için uygulamaya konulan yöntemlerden biri de Nisan 1910 yılında
uygulamaya konulan ihtiyat zabitanı teşkilatıdır. Bu teşkilat barış dönemlerinde birliklerde subay sayısı azaltılmış olduğundan, savaş ve sefer dönemlerinde yedek efrada gerekli eğitimlerin verilmesi için ihtiyaç duyulan subayların
temini amacıyla kurulmuştur. Redif ve müstahfız birlikleri, sadece sefer halinde silahaltına alınan efrattan oluştuğu için eğitim yönünündün yetersiz olmalarının yanı sıra, ileri yaşlarda olmaları nedeniyle beklenen faydayı sağlayamamıştır.
Buna bir de idaredeki yetersizlik ve modern silahlara sahip olunmaması eklenince savaşlarda başarısızlıklar kaçınılmaz olmuştur. Bunun sonucu olarak Balkan Harbi’nden sonra redif sınıfı ordu teşkilatından çıkartılmıştır, müstahfız
ve itiyat zabitanı adı verilen yedek subaylık uygulaması Birinci Dünya Savaşı yıllarında da uygulanmaya devam edilmiştir.
Adaptation Of Evolution Knowledge Test İnto Turkish
Authors: Avan Oğuzhan , Kayıklık Hasan
Published: December 2023

Evrime yönelik tutumlar konusunda Türkiye’de özellikle sosyal bilimler alanında yeterli nicel araştırmaların olmadığı görülmektedir. Nicel yöntemlerle araştırma yapabilmek için ölçme araçlarına ihtiyaç vardır. Bu nedenle bu çalışmanın
amacı, evrim bilgi testini Türkçeye uyarlamaktır. Hem fen bilimlerinde hem de sosyal bilimlerde evrim üzerine yapılacak çalışmalarda katılımcıların evrim bilgisinin önemli bir değişken olacağı düşünülmektedir. Türkiye'de evrim
bilgisine yönelik testler bulunmakla birlikte, soru sayısının fazla olması ve genellikle evrim eğitimi almış bireylere yönelik geliştirilmiş olması nedeniyle bazı sınırlılıklar bulunmaktadır. Türkçeye uyarladığımız evrim bilgi
testinin 10 sorudan oluşması ve biyoloji alanı dışındaki bireylere de uygulanabilir olması bir avantajdır. Test çoktan seçmeli sorulardan oluştuğu ve bir başarı testi olduğu için, soruların evrensel bilgiyi ölçtüğü düşünüldüğünden
kültürel farklılık olmayacağı anlaşılmıştır. Testin içerik ve dil geçerliliği alan uzmanları tarafından sağlanmıştır. Testin Türkçe versiyonu 305 genç yetişkine uygulanmış ve veriler toplanmıştır. Madde güçlük ve madde ayırt edicilik
analizleri yapılmıştır. Madde güçlük ve madde ayırt edicilik analizlerinin sonuçlarına göre, her bir madde ve testin bütünü beklenen değerler arasındadır. İç tutarlılık güvenirliği Kuder Richardson 20 (KR-20) ile kontrol edilmiştir.
KR-20 .670 olarak belirlenmiştir. Bu katsayı, bir başarı testi için yeterlidir. Testin beklenen madde güçlük ve madde ayırt edicilik değerlerini sağladığı belirlenmiştir. Sonuç olarak, evrim bilgi testinin Türkçe versiyonu kullanıma
sunulmuştur.
An Analysis of 2018 Geography Course Curriculum for 11th and 12th Grade Learning Outcomes Depending on Webb’s Depth of Knowledge Taxonomy
Authors: Demiralp Nurcan
Published: December 2023

Çalışmada 11 ve 12. sınıf coğrafya dersi öğretim programında (2018) bulunan kazanımların, Webb’in bilgi derinliği taksonomisine göre analizinin yapılması amaçlanmıştır. Webb’in bilgi derinliği seviyelerine göre analiz edilmesinin alan
yazına ve program hazırlayıcılara katkı sağlayacağının düşünülmesinden dolayı çalışmanın literatüre katkı sağlayacağı düşünülmüştür. Buna göre yapılan çalışma, doküman incelemesi yöntemi ile gerçekleştirilmiştir. Coğrafya dersi
öğretim programı, Webb’in bilgi derinliği taksonomisinin dört seviyesi, sosyal bilimler için belirlenen fiiller ve kazanımların kapsamı da göz önünde bulundurularak analiz edilmiştir. Bu kapsamda Coğrafya dersi öğretim programında
bulunan 11. sınıfta 29 kazanım, 12. sınıfta 24 kazanım olmak üzere toplamda 53 kazanımın sınıf ve ünitelere göre seviyeleri incelenmiştir. Webb’in bilgi derinliği taksonomisinde, kazanımların sınıflar, üniteler ve seviyeler arasında
dengeli dağılmadığı tespit edilmiştir. Buna göre 11. sınıfta yer alan 29 kazanımın on beşi Seviye 3’te yalnızca biri Seviye 4’te bulunurken; 12. sınıfta yer alan 24 kazanımın yarısı Seviye 1’de bulunurken Seviye 4’te herhangi bir
kazanım bulunmamaktadır. Bu sonuç karmaşıklık seviyesinin fazla olduğu görevlerin yer aldığı ünitelerde öğrencilerden beklenen düşünce düzeyindeki esneklik ve derinliğin gerçekleşemeyeceğini göstermektedir. Ayrıca hem 11. sınıf
hem de 12. sınıf kazanımları Webb’in taksonomisine göre analiz edildiğinde birden fazla seviyenin en fazla yer aldığı ünitenin beşerî sistemler ünitesi olduğu en az kazanımın ise derinlemesine düşünme seviyesinde olduğu tespit
edilmiştir. Analiz sonuçlarından da anlaşıldığı üzere 11. ve 12. sınıf CDÖP’de hatırlama ve stratejik düşünme seviyelerinde kazanımların daha çok yer aldığı, buna karşılık beceriler ve derinlemesine düşünme seviyelerinde kazanımların
yetersiz kaldığı görülmektedir. Bu göstergeler, 11. ve 12. sınıf CDÖP’nin anlamlı öğrenmeyi gerçekleştirmede yeterli derecede etkili olmayacağı kanaatini oluşturmaktadır. Bu nedenle bilgi derinliği için öğretme ve öğrenmenin titizlikle
planlanması gerekmektedir.
Yunus Emre and Morality
Authors: Kadğa Erkan , Koluman Hilal , Kurt Hüsamettin , Bozdağ Reşit
Published: December 2023

Yunus Emre, 13. yüzyıl Türk şairleri arasında öne çıkan bir isim olarak sadece şiirleriyle değil, aynı zamanda güzel ahlakıyla da bilinir. Eserlerinde insan sevgisi, birlik, sevgi ve hoşgörü gibi evrensel değerleri işleyen Yunus Emre,
güzel ahlakın insanın karakterinin temel taşı olduğuna vurgu yapar. Onun ahlaki düşünce yapısı, insan sevgisiyle iç içe geçer ve güzel ahlakın toplumsal düzeni güçlendireceğini savunur. Yunus Emre'nin öğretileri, günümüzdeki insanlara
güzel ahlakın önemini hatırlatma ve toplumsal ilişkilerde hoşgörüyü teşvik etme açısından güncelliğini korumaktadır. Yunus Emre'nin eserleri, insanlığa sevgi ve güzel ahlakla yaklaşma çağrısı yaparak, onun düşünce dünyasını günümüze
taşır.
Candidates on the Mathematics Course of Presentations Made with Activities in Excel: Gazi University Example
Authors: ERCAN Leyla , Ercan Leyla
Published: December 2023

Bu çalışmanın amacı matematik bölümü 3.sınıfta öğrenim görmekte olan öğretmen adaylarının Excel kullanılarak yapılan sunumların matematik dersine yönelik görüşlerini ortaya koymaktır. Böylece matematik öğretmen adaylarının matematik
konularını teknoloji destekli sunumlarla yaptığında eksiklerini görmeleri, görsellerle nasıl destekleyeceklerini bilmesi, matematiği nasıl eğlenceli hale getirebileceğini öğrenmesi, ileride öğretmen olduklarında konuları nasıl
anlatabileceği konusunda farkındalık yaratılmak istenmiştir. Araştırmanın çalışma grubu 2023-2024 eğitim öğretim yılı Gazi Üniversitesi Gazi Eğitim Fakültesi İlköğretim Matematik Öğretmenliği Bölümü 3.sınıfta okumakta olan 77 (64
Kız- 13 Erkek) öğrenciden oluşmuştur. Matematik Öğretiminde İlişkilendirme dersinde araştırmacı tarafından 4 hafta boyunca yapılacaklar hakkında bilgi verilmiştir. Öğrencilerden her dersin sonunda Excel’de etkinliklerle yapılan
sunumların matematik dersine etkilerinin ne olduğuna ilişkin görüşlerini yazmaları istenmiştir. Veri toplama araçları, matematik dersine yönelik öğrenci görüşlerinin yer aldığı bilgisayar ortamında hazırlanmış bu belgelerden oluşmuştur.
Öğrenci görüşlerine göre gelecekte öğretmen olarak görev yaptıklarında da teknoloji destekli öğretimin öneminin farkına varmışlardır ve kullanmak istediklerini belirtmişlerdir.
EVALUATION OF TURKISH UNIVERSITIES IN THE CONTEXT OF DIALOGIC COMMUNICATION ACCORDING TO URAP 2020-2021 REPORT
Authors: AYDOĞAN KILIÇ TUĞÇE , TAŞCIOĞLU RACİ
Published: December 2023

Halkla ilişkiler alanına son yıllarda kazandırılan ilişkisel perspektif, kurumların paydaşları ile ilişki oluşturması ve sürdürmesinin temeline diyalog kavramını yerleştirmektedir. İnternet teknolojilerinde yaşanan gelişmeler ile değişen
dünyada halkla ilişkilere yüklenen anlam ve önem de değişmiştir. Kent ve Taylor (1998), internetin kurum ve paydaşları için önemli bir diyalog aracı olduğunu ve diyalojik halkla ilişkilerin web ortamı ile bütünleşmesi için kurumların
web sayfalarını beş ilkeyi temel alarak oluşturmaları gerektiğini ifade etmişlerdir. Bu ilkeler: diyalojik döngü, enformasyonun yararlılığı, yeniden ziyaret sağlama, arayüzün kullanışlılığı, ziyaretçilerin korunması şeklindendir.
Çalışmada, URAP 2020-2021 listesinde ilk 5’te yer alan devlet ve vakıf üniversitelerinin resmi Twitter hesaplarındaki diyalojik iletişim düzeyleri analiz edilmeye çalışılmıştır. Çalışmada Twitter’ın standart bir arayüze sahip olması
nedeniyle “arayüzün kullanışlılığı” ilkesi değerlendirmeye alınmamıştır. Bu çalışmanın amacı örneklem olarak seçilen 10 üniversitenin 12 Nisan- 12 Mayıs tarihleri arasında Twitter profillerinde nasıl ve ne şekilde diyalojik iletişim
sergiledikleridir. Üniversitelerin Twitter hesapları içerik analizi yöntemi ile incelenmiştir. Araştırmada daha önce yapılan çalışmalardan uyarlanan bir araştırma modeli kullanılmıştır. Araştırmada elde edilen bulgulara göre, devlet
üniversitelerinin vakıf üniversitelerine kıyasla daha fazla içerik paylaşımı yaptıkları görülmüştür. Diyalojik iletişim ilkelerinin hem devlet hem vakıf üniversiteleri tarafından kullanılsa da düzeylerinin düşük olduğu sonucuna
varılmıştır.
The New Professionalism Character in Education: Framing the Management Issue
Authors: Prasetyo Muhammad Anggung Manumanoso , Fadhli Muhammad
Published: December 2023

Professional character development necessitates a variety of outcome-based evaluation strategies. This article suggests modifying the concept and substance of the lecturer evaluation system to improve professional lecturer characteristics. Qualitative research using the grounded approach, technological data mining, and experience Data analysis on MPI professional practice at IAIN Lhokseumawe utilizing analytic research. The study's research boundaries represent instructors' professional competency in the aims of the Tri Dharma of higher education. The results of the study revealed that the new subject offered by the MPI IAIN Lhokseumawe. To begin, lessons learned about professional traits based on religious beliefs and job evaluations have implications for classroom instruction, research, and community outreach. Second, the identification of empirical indicators of professionalism outcome attainment is identified by performance assessment reports and procedures for building a culture of professionalism that is regarded as ideal for formalization through a reward and punishment system. Third, professional growth in higher education is accomplished by strategic evaluative personal skills, substantial education, institutional training, job autonomy, and adherence to an ethical code. When the principle of professionalism is studied, the practical implication will be the establishment of a global management professional who will contribute qualitatively to the demands of the industrial world and raise the growth of the global economy as a whole.
The Development of Crello-assisted E-Modules to Train Critical Thinking Skills on Elasticity and Hooke's Law Material
Authors: Rahmayanti Dinda , Risdianto Eko , Hanisa Putri Desy
Published: December 2023

The research sought to determine the appropriateness and learners’ perceptions of the Crello-assisted E-Modules to Train Critical Thinking Skills on Elasticity and Hooke's Law Material. The research utilized the ADDIE (Analyse, Design, Development, Implementation, and Evaluation) development model. 1) The appropriateness results of the Crello-assisted E-Modules to Train Critical Thinking Skills on Elasticity and Hooke's Law Material had a mean percentage value of 87.67%; thus, it was in the Highly Appropriate category. 2) The findings of learners perceptions of e-modules were in the Excellent category, with a mean percentage value of 83.06%. Based on the validation and readability tests conducted on learners’ in High School/Islamic High School, the generated e-modules were extremely suitable for future use. The advantages of e-modules were that lies in their attractiveness, including can even be used anywhere and anytime, moreover could further build up learners’ critical thinking skills.
Digital Literacy Learning Management Innovation at State Vocational Schools in Manado City
Authors: Koessoy Herman , Katuuk Deitje Adolfien , Lengkong Jeffry S J , Rotty Viktory Nicodemus Joufree
Published: December 2023

This article aims to describe innovations in digital literacy learning management for students at State Vocational Schools in Manado City. This research is a qualitative research in which the data collection process is carried out through interviews, observation and documentation. From the research conducted, it is known that SMK schools in Manado City innovate in 3 ways, namely: Changing the teacher's paradigm of conventional education towards modern education with education and training activities and educational seminars and through improving academic qualifications, secondly Providing digital literacy skills to teachers, education staff and students through digital literacy workshops and training activities related to the use of the latest learning and learning media and technology and the third is by providing facilities and infrastructure that can be utilized by students, teachers and education staff to support digital literacy activities in the school environment. This method is considered appropriate and quite successful in encouraging all components of the school to learn and improve their respective human resources regarding digital literacy.
Islamic Education Funding Management at MTs Miftahul Ulum Jember
Authors: Taufik Taufik , Zaini Zainuddin Al Haj , Fauzi Imron
Published: December 2023

the purpose of this study is to find out and analyze the management of Islamic education financing at Madrasah Tsanawiyah Miftahul Ulum Jember which is focused on 1) Funding Sources and 2) Educational Financing Planning contained in the RKAM. The research method uses a qualitative approach . Data was collected through the process of observation, interviews and documentation with the head of the madrasa and administrative staff. The results of the study revealed that MTs Miftahul Ulum is a formal institution under the Miftahul Foundation Ulum has a source of education financing income based on observations through BOSDA, BOSNAS and Voluntary Assistance (SPP) as stated in the RAPBM MTs Miftahul Ulum . MTs Miftahul financing planning Ulum is contained in the Draft Madrasah Revenue and Expenditure Budget, where the steps include: 1) Each person in charge of the 8 Competency National Education Standards that has been formed by the Madrasah Head makes budget planning according to targets and needs taking into account the scale of needs, namely short term and long term , 2) Previously the Madrasah Head had formed a team in charge of making the Madrasah Activity Plan (RKM) for the 2018 – 2022 period, 3) The Madrasah Head and the team in charge of RKM carried out matching the budget proposed by the person in charge 8 Competence of National Education Standards with the Vision and Mission of the Madrasa within a period of time In the next 4 years , 4) Approval meetings are enacted in making the RKM which involve all madrasah stakeholders. The following is the Madrasah Activity Plan and Budget at MTs Miftahul Ulum.
The Leadership Planning and Education Quality of Salafi Islamic Boarding Schools
Authors: Syihabudin Tubagus , Syafuri B , Fauzi Anis
Published: December 2023

Salafiyah Islamic boarding schools aim to teach and practice the Al-Qur'an and Al-Hadith based on understanding the best generation. The issue of leadership regeneration and education quality is the weakness of Salafi Islamic boarding schools (IBS) because it is carried out suddenly and seems to lack attention. Integrating these educational goals requires leadership and quality based on planning so they can compete equally with other educational institutions. The research aims to analyse leadership planning in achieving Salafi IBS. The research method uses qualitative with a grounded theory approach at the Salafiyah At-Thahiriiyah IBS in Serang City and data collection by interviews and literature study. The research results show leadership planning and quality of education in Salafiyah IBS through increased leadership training, scientific capacity and education quality standards in Salafiyah IBS. There is a strengthening in the leadership planning of Salafiyah IBS through gradual leadership regeneration. The implications of research by strengthening leadership planning on the quality of education can use a design thinking approach that will help solve internal problems through leadership training, scientific capacity, gradual regeneration and education quality standards in Salafiyah IBS.
Learning Media in Active Learning Time of Elementary School Students
Authors: Winata Ardi
Published: December 2023

The purpose of this study was to obtain a description of "Utilization of Physical Education Learning Media in an Effort to Increase Students' Active Learning Time". The method used in this research is The Classroom Action Research. The design used in this study is a cyclical model which includes the steps of planning, implementing, observing, and reflecting. The population used by purposive sampling, as many as 32 fourth grade students. The instrument used is in the form of field notes (Duration Recoding), namely the use of active time to learn physical education through observation with an average of 60% so that the target achievement is determined with an average of 90%. Based on research in cycle I (Actions I, II and III) 90.43%, because it has exceeded the research target, it is completed in cycle II. Based on the results of data analysis, it is concluded that the use of physical education learning media is quite significant in increasing the active learning time of students at SMPN 01 Madang Suku 1 District in OKU Timur.
Teacher Well-Being: the Teachers Perspective in the Special Region of Yogyakarta
Authors: Hidayati Dian , Sukmayadi Trisna , Luthfi Imama Mohammad , Fadlan Syakir Muhammad
Published: December 2023

The role of a teacher is vital to creating an effective and efficient educational process. Not everyone can become a teacher or lecturer because they are considered a profession that demands professionalism. Nonetheless, the role of a teacher in the educational process is not commensurate with the welfare conditions felt by the teachers; the workload is quite heavy, with emotional demands causing negative suggestions for teachers regarding their work. It is appropriate for policymakers related to the world of education to pay more attention to the construct of well-being in teachers. The aim of this research, thus, is to discover teachers' perspectives on teacher well-being that they experience while being teachers, starting from two attitudes in implementing teacher well-being (affective and cognitive), as well as what factors make them persist as teachers. This research used qualitative methods. The informants involved in this research were five teachers in the Special Region of Yogyakarta. Based on the data collection method, a triangulation test of sources, techniques, and time was carried out to test the validity of the data. This research revealed six aspects of teacher well-being, encompassing positive relationships with other people, autonomy, personal growth, environmental mastery, self-acceptance, and purpose in life. Family support and a positive view of the teaching profession are essential to improving teachers' well-being.
Keanekaragaman Fungi Mikoriza Arbuskula pada Tegakan Kelicung (Diospyros macrophylla Blume) di KHDTK Rarung, Lombok Tengah
Authors: Utami Desty Sasana Putri , Mansur Irdika , Hilwan Iwan , Haryantini Baiq Azizah
Published: December 2023

Kelicung tree (Diospyros macrophylla) is a native tree species of West Nusa Tenggara. It is a slow-growing tree with very good wood ornament, strength, and durability properties. Symbiotic mutualism between kelicung and mycorrhiza has not been documented. Mycrorrhiza is a mutualism symbiosis between fungi and plant roots that could improve plant growth due to increase nutrient and water absorbtion. Therefore, the objective of this study is to investigate mycorrhizal symbiosis in kelicung roots. Soil and root samples were taken in the Rarung Special Purpose Forest Area at 0 – 20 cm depth. Isolation and identification of arbuscular mycorrhizal fungi used screening and centrifugation methods to identify spore density, diversity, abundance, and frequency. Furthermore, root staining and colonization of arbuscular mycorrhizal fungi were carried out by observing the structure of vesicles, arbuscules, hyphae, and spores on Kelicung roots. The research results showed that the average number of spores found was 846 spores/50 g of soil. Spores were identified in two genera: Glomus sp and Acaulospora sp. Glomus spores found were round, the colour of the spores was yellow, the spores did not react when Melzer's solution was dropped, and the spore walls of the Arbuscular mycorrhizal fungi of the genus Glomus consisted of 1-2 layers of cell walls. Observation of root colonization, no structures of root arbuscular mycorrhizal fungi were found in Kelicung.

Keywords: Acaulospora sp., Arbuscular mycorrhizal fungi, Diospyros macrophylla, Glomus sp., Kelicung
Species of Fungi Involved in the Decomposition of Rhizophora apiculata Leaf Litter on Pulau Sembilan
Authors: Yunasfi Yunasfi , Lestari Sri , Utomo Budi , Dalimunthe Afifudin , Fadhilah Amanatul , Noer Zulheri , Sihite Yunita , Samosir Putri Anatasia , Auri Mahla Rose Alba , Ramadhan Yudha Ilham
Published: December 2023

Rhizophora apiculata is one of the mangrove species that grows in coastal areas influenced by seawater. Decomposing leaf litter from R. apiculata is an organic material needed by microorganisms and organisms to grow and develop in the environment where they live. Microorganisms involved in accelerating the decomposition process are fungi. This research activity was carried out for six months, from June to December 2022. This research method uses litter bags to store leaf litter, which will be isolated and the rate of decomposition calculated. The results showed that there were 3 genera of fungi, namely Aspergillus sp., Trichoderma sp., and Penicillium sp. The decomposition rate of R. apiculata leaf litter was 0.13/day. The average carbohydrate content was 8,78%, and the average protein content was 5,45%.

Keywords: Decomposition, Fungus, Litter, Rhizophora apiculata
Cultivating Sustainability: Exploring the Relationship between Homestead Gardening, Land Property, and Family Economic Pressure in Household with Stunting Children
Authors: Barai Sultan Azis , Nurmahfuzhah Nisrina , - Defina
Published: December 2023

The impacts of climate change exacerbate the problems of food insecurity and malnutrition, especially child stunting. This study aims to characterize households with stunted children and explore the relationship between yard agroecosystem management strategies, yard ownership, and family economic stress. The study was conducted among 68 households with stunted children in Sumedang District, West Java, selected using purposive sampling. The results found that only 11.7 percent had a dedicated yard with a low level of cultivation and utilization of agrobiodiversity. Correlation analysis showed that the husband's education level was significantly positively associated with yard ownership and utilization. The husband's age and family size were significantly positively related to objective economic pressure. The wife's education and per capita income were significantly negatively related to objective economic pressure. Meanwhile, subjective economic pressure was significantly negatively related to per capita income and significantly positively related to objective economic pressure.
Mosquito Community in Primate Captivity (Tarsius sp.) and its Potential as Transmitters of Zoonotic Mosquito-Borne Diseases.
Authors: Cécile Sarasvathi , Upik Kesumawati Hadi  , Uus Saepuloh  , Sela Septima Mariya  , Huda Shalahudin Darusman
Published: December 2023

By means of conservation, ectoparasites monitoring and surveillance especially mosquitoes in primate captivity become important. Mosquito is one of the ectoparasites which acts as a vector of various types of zoonotic diseases such as Dengue, Zika, Japanese encephalitis, Rift Valley fever, filariasis, and others. This study was aimed to determine the diversity of mosquito species, their fluctuations as well as the potential of mosquitoes as a Dengue virus (DENV) vector around the tarsier captivity in the animal conservation laboratory IPB Primate Research Center (IPB PRC). Mosquitoes were collected from February to April 2020 using light traps and sweep net every two hours from 06.00 pm to 06.00 am. Detection of the presence of Dengue virus (DENV) is carried out using Reverse Transcriptase Real-time Polymerase Chain Reaction (RT-qPCR) against Aedes albopictus and Armigeres subalbatus. The results showed that there were 4 species of mosquitoes caught around the tarsier captivity namely Aedes albopictus, Culex quinquefasciatus, Armigeres subalbatus, and Armigeres foliatus. The dominant mosquito species were Armigeres subalbatus (62.11%) and Aedes albopictus (41.61%). Detection of Dengue virus (DENV) serotypes 1, 2, 3, 4 in Aedes albopictus and Armigeres subalbatus gave negative results. The presence of mosquitoes that have the potential to carry zoonotic disease around the tarsier captivity in IPB PRC shows the potential for Mosquito-Borne Diseases to both tarsiers and human.
Studies on the Influence of Charge Inducer and it’s Combination with P-gp Inhibitor to Improve the Oral Bioavailability of Nimodipine via Submicron Lipid Emulsions
Authors: Sara Fathima , Veerabrahma Kishan
Published: December 2023

Background: Nimodipine (NM), is a dihydropyridine calcium channel blocker with poor oral bioavailability (BA) of about 13% due to first-pass metabolism and P-gp efflux. Objective: The present work aimed to study the influence of the charge inducer and its combination with P-gp inhibitor to improve the oral bioavailability of NM by developing a suitable delivery system of Submicron Lipid Emulsion (SME). Methods: Five SME formulations of NM were prepared by homogenization followed by ultrasonication. Prepared SMEs were characterized for particle size, PDI, Zeta Potential (ZP), Entrapment Efficiency (EE), and drug content. In vitro, release studies were performed in 0.1N HCl and pH 6.8 phosphate buffer by open tube method. The physical stability of all NM–SMEs was tested by the individual effects of centrifugation, dilution (desorption stress), and storage. Bioavailability studies were conducted on male Wistar rats after oral administration of NM suspension and F1 to F5 SME formulations. Results and conclusion: Five NM- SMEs were developed with a mean size ranging from 93 - 137 nm, Zeta potential of – 26 ± 1 mV (negatively charged), +45.8 to +46.3 mV (positively charged), and PDI of 0.15 - 0.25. The in vitro release studies showed that relatively more cumulative percentage release of NM – SMEs in 0.1N HCl than in pH phosphate buffer during 24 hours. The physical stability of NM–SMEs indicated that they were stable to the effects of centrifugation, dilution, and storage. Pharmacokinetic (PK) studies showed that the oral bioavailability of NM in F4 SME was significantly higher than that of all other formulations. Taken together, the results indicated the development of a stable lipid-based carrier, F4 SME to improve the oral bioavailability of this drug by minimizing first-pass metabolism due to lymphatic transport, reducing the efflux by P-gp inhibition, and further, by increased uptake of the positively charged F4 SME globules by enterocytes. Future: The research study findings increase the possibility of developing NM F4 SME by the pharmaceutical industry for the patient’s benefit.
Home medical care and Home health care system and roles of the public health care in Korea
Authors: Lee Kun-Sei
Published: December 2023

In the face of rapid aging in Korea, the demand for appropriate medical services for the elderly at home is increasing. This study investigates the current status of home medical care and Home health care in Korea based on the concept of Home-based primary care, and proposes strategies to implement home-care in public health centers and public hospitals that play a major role in the field of public health care.First of all, by presenting a conceptual framework for the current status of Korea’s home medical care and Home health care provision system, and described according to three financial resources: National Health Insurance(NHI), Long-Term Care Insurance(LTCI), and public health care. At the current level, the home health care systems are fragmented and they should be redesigned to improve the home care services.In order to implement home care in public health care institutions, a model centered on public health centers and public hospitals is proposed. Public health centers have various advantages, responsibility positions, and access to information, but they have working conditions and difficulties in providing incentives, and medical and nursing limitations. Public hospitals can provide a variety of services, but community access and insufficient knowledge are pointed out as disadvantages. Therefore, it is important to establish a cooperative system between the two institutions.Finally, we proposes the division and cooperation between public health centers and private medical institutions according to the level of service. Private medical institutions could be in charge of active treatment, medical services and skilled nursing cares. public health centers could perform monitoring and follow-up the patients. it is necessary to establish a coordinating system to cooperate the two parts of institutions.
Atención de enfermería en preescolar con atresia pulmonar en oxigenación con membrana extracorpórea: caso exitoso
Authors: Lizcano-Villamizar Lady Carola
Published: December 2023

Introducción. La atresia pulmonar con comunicación interventricular es una cardiopatía compleja que enmarca grandes desafíos en su etapa pre y postquirúrgica; el uso del soporte vital extracorpóreo con membrana de oxigenación restablece la oxigenación y perfusión al organismo para permitir recuperación y complementar estudios. El objetivo de este caso clínico es determinar la atención de enfermería en la fase aguda post quirúrgica. Se expondrá usando el modelo teórico de Dorothea Orem: teorías de déficit de autocuidado y teoría de sistemas. Esta cardiopatía es la forma más severa de la tetralogía de Fallot. Tiene una incidencia del 2% entre todas las cardiopatías. Metodología. Es el caso de una preescolar con atresia pulmonar con comunicación interventricular, se describe los procesos realizados desde el diagnóstico, la intervención percutánea y reparo quirúrgico, así como el manejo de lesión residual en el marco del uso de diferentes tecnologías. Se resalta como elemento clave el uso del soporte con oxigenación con membrana extracorpórea usada como puente a decisión. Resultados. El plan de atención de enfermería en esta fase crítica logró los resultados planteados como la adecuada perfusión y oxigenación, recuperación de la función ventricular, estabilización hemodinámica para para ser llevada al reparo de la lesión residual. Este novedoso soporte fue implementado dos veces durante la misma hospitalización y con resultados exitosos. Conclusiones. Caso de difícil manejo con terapias convencionales, pero con aplicación de una atención integral de enfermería; el uso de tecnología y de diversas especialidades permitió un egreso de la menor sin complicaciones.
Analisis Financial Distress Dengan Metode Altman Sebagai Prediksi Kesehatan Keuangan Perusahaan
Authors: Nandini Indira , Mudjiijah Slamet
Published: December 2023

Penelitian yang dilakukan memiliki tujuan mempermudah perusahaan dalam mendapatkan informasi mengenai gejala-gejala Financial Distress untuk memprediksi kesehatan keuangan suatu perusahaan. Hasil penelitian dapat digunakan sebagai sumber acuan informasi kepada perusahaan apabila dalam kondisi Financial Distress maka perusahaan perlu mengantisipasi dan meningkatkan kinerja keuangannya. Data sekunder yang digunakan diperoleh dari www.idx.co.id dan www.idnfinancials.com beserta website perusahaan terkait. Metode purposive sampling sebagai teknik pemilihan sampel dengan pendekatan kuantitatif deskriptif sehingga diperoleh 15 perusahaan manufaktur subsektor makanan dan minuman yang terdaftar di Bursa Efek Indonesia periode 2016-2020. Metode analisis yaitu Altman Modifikasi. Hasil dari penelitian ini menjelaskan bahwa pada metode Altman Modifikasi terdapat 11 perusahaan dalam kondisi sehat, 1 perusahaan dalam kondisi (grey area) abu- abu dan 3 perusahaan dalam kemungkinan bangkrut.
Perubahan Organisasi Dengan Pendekatan Diagnosa Pestle Model Pada Bank X
Authors: MJP Arif Wibisana , Kadiyono Anissa Lestari
Published: December 2023

Penelitian ini bertujuan untuk menganalisa keadaan Bank. X sebagai dasar dilakukannya langkah perubahan dan pengembangan organisasi Bank. X kedepannya menggunakan analisa PESTLE model. Peneliti melakukan wawancara pada 1 orang Brand Manager dan menyebarkan kuesioner pada 3 orang karyawan Bank. X. Hasil penelitian menunjukkan bahwa terdapat beberapa perubahan yang dirasakan secara langsung maupun tidak langsung terhadap perusahaan. Perubahan yang terjadi dan harus dipatuhi oleh Bank. X adalah perubahan Undang-Undang atau Hukum sehingga regulasi ini sangat banyak dan berubah setiap tahun bahkan setiap bulan. Namun terkadang beberapa regulasi ini menghambat pencapaian target karyawan/KPI. Maka dari itu beberapa karyawan menolak untuk berubah sesuai dengan regulasi saat ini. Dengan begitu saran yang dapat diberikan kepada Bank. X adalah intervensi yang bersifat kuratif yang bertujuan untuk membuat karyawan menerima setiap perubahan yang terjadi. Karyawan diberikan kesadaran untuk menerima bahwa regulasi dari Bank Indonesia dan OJK wajib untuk diikuti.
Analysis of a sudden release of a gas-coal mixture from a conical cavity formed during the gas outburst
Authors: Cherdantsev S.V. , Shlapakov P.A. , Lebedev K.S.
Published: December 2023

Indispensable attributes in underground coal mining are methane and coal dust of various particle sizes. When they are mixed, coal-gas mixtures are formed, predisposed to various hazardous and extremely hazardous gas-dynamic phenomena, primarily to sudden emissions, accompanied by formation of cavities in the coal massif and intensive release of coal-gas mixtures from these cavities into the mine workings. The article deals with the problem of a one-dimensional stationary flow of a gas-coal mixture in an underground cone-shaped cavity formed during a sudden release. The Euler equation of motion and the continuity equation are used as the basic equations. As a result of their transformation, an ordinary differential equation of the first order is obtained, for which the Cauchy problem is formulated. The solution to the Cauchy problem is a transcendental equation with respect to the desired Mach numbers. The roots of the transcendental equation are calculated using the MathCAD mathematical software suite. Upon finding the Mach numbers, the remaining parameters of the mixture are determined, i.e. the pressure, density and temperature of the gas-coal mixture at any point in the conical region, including their critical values. Graphs are constructed that were used as the basis to establish some regularities of the one-dimensional stationary flow of a gascoal mixture in a conical region. In particular, it was found that with an increase in the Mach number, parameters of the gas-coal mixture decrease non-linearly, and with an increase in the Poisson's adiabatic index, the pressure and temperature decrease, and the density increases.
Social and economic development of the mountainous region of Russia: challenges and growth prospects
Authors: Oorzhak V.O. , Dongak Ch.G. , Manchyk-Sat Ch.S. , Mongush A.K. , Sevek R.M.
Published: December 2023

The paper presents the results of studying the main challenges and searching for opportunities to ensure dynamic social and economic development of the Republic of Tyva, a mountainous depressive subject of the Russian Federation, located near the eastern border of the country. Based on analysis and synthesis of indicators from various periods of the region's development, irregularity (instability) of its dynamics is demonstrated. The paper reveals the main reasons for lagging behind and the development factors. The need for a more detailed research into the specific features of this region is emphasized with due account of these differences in the development of the state regulatory measures in relation to similar territories of the country. The authors make the following pilot proposals to develop preferential regimes within the territory of this mountainous and problematic subject of the country: (1) to achieve the level of average per capita monetary income of residents in the amount of 40 thousand rubles (the average Russian level), it is necessary to increase the GRP of the region at least to 110-150 billion rubles, (2) to ensure the growth of average per capita monetary income of the residents of this region to reach 800 USD per month (the average European level), it is necessary to increase the gross regional product to 350.0 billion rubles. Such indicators can ensure dynamic social and economic development of the Republic of Tyva.
Development of a surface coal mining operation using an ecosystem approach
Authors: Cherskikh O.I. , Makarov A.M.
Published: December 2023

In its activities, an open-pit coal mining company comes into contact with the natural, mining and geological environment, interacts with a significant number of organizations, institutions, enterprises, state and municipal governments. In order to balance the interests of this community, as well as to take into account the effects on the natural, mining and geological environment, it is advisable to use an ecosystem approach in planning and organizing the development of the company, which is aimed at combining and using the potential of the stakeholders to mutually strengthen the development opportunities and achieve both individual and collective goals. Ensuring the high quality of the company's production process is considered as the main means of achieving a balance of interests of ecosystem actors. The quality of the production process is determined by the level of the four process components, i.e. personnel, equipment, working conditions, and process organization. Application of the ecosystem approach is described using the example of the Solntsevsky coal mine, where organizational and technological solutions are designed and implemented to improve the quality of the production process, as well as a situational and analytical center is developed and digitalization of production is introduced.
Alternating electric current in coal mines: electromagnetic energy and its conversion into electric current
Authors: Kolesnichenko I.E. , Kolesnichenko E.A. , Lyubomishchenko E.I. , Kolesnichenko E.I.
Published: December 2023

The article addresses the challenge of improving the competence and basic knowledge of specialists working with alternating electric current. The purpose of this work is to explain the magnetic properties of substance, generation of magnetic field and electric current with due account for the known laws of physics and the Quantum theory. We believe that addressing these tasks needs to begin with the energy produced by the magnet. The method of inducing electric energy using magnetic field of a permanent magnet is chosen as the research subject. The historical mythological bases of interpreting the induction of electric energy are shown. Modern instruments prove that the magnetic field is the electromagnetic emissions of magnets. A hypothesis regarding the origin of magnetic properties of substance is developed based on analysis of the known magnetic properties of alpha-iron. Two features of the magnetic properties of substance have been revealed, which differ from Ampere's ideas. The first is the local volume of atoms combined by short-acting covalent bonds, forming a natural crystalline or artificially elongated structure. The second is that the frequency of electromagnetic emissions by the valence electrons of all the atoms in Hertz is approximately the same. The total radiation of energy by all the atoms in local formations generates a magnetic field. The hypothesis is confirmed by circuits and information on instruments that measure the emission of magnets in Hertz. When the energy absorbed by electrons increases, the bond between atoms is broken and magnetic emissions cease. All substances in liquid and solid aggregate state begin to radiate electromagnetic emissions to other substances under the impact of external electromagnetic emissions. This is confirmed by photographic evidence of the performed experiments. A hypothesis is proposed, which differs from the ideas about the movement of free electrons by the fact that the formation of electric current is the result of absorbing electromagnetic emissions of the magnet by valence electrons of the electrical conductor and their transfer into the electric network. The physical phenomena of energy transfer between the transformer windings in an electric circuit prove that electric current is a concentrated flow of electromagnetic emissions, which are a wave form of energy.
Assessment of the ventilation network condition within the Le-3 ore body at the Juliet deposit
Authors: Arno V.V. , Volin A.M. , Kalinina L.Yu. , Garifulina I.Yu. , Lomakina N.E. , Elnikova E.A.
Published: December 2023

Effective, high-quality and steady ventilation of mine workings is one of the main factors that determine safe working conditions in an underground mine. The Juliet deposit is characterized with an irregular shape and varying dips and strikes. In some cases, it consists of isolated and mutually remote deposits with different mining and geological characteristics. These features of the deposit dictate the use of complex schemes for the development and mining of the deep-lying layers, which results in formation of a very extensive and branched network of underground workings. The specific features in the development of the Juliet deposit include the fact that a large number of mining blocks are in operation at the same time, and extraction of these block can be carried out using different mining systems. Intensive removal of dust and gases can be ensured only when a sufficiently large amount of air is supplied to the mine and the individual working faces. In order to overcome the overall air drag in the mine, it is necessary to use high-performance and high-pressure fans that would consume enormous power.
Justification for the choice of emulsion explosives production and delivery method when introducinga new technological mode at high-capacity coal mines in Kuzbass
Authors: Pytalev I.A. , Domozhirov D.V. , Borisenko E.V. , Iltinin Yu.K.
Published: December 2023

The sphere and conditions for application of the water-in-oil type of emulsion explosives in deposits of the Southern Urals and Kuzbass have been justified. Two sub-classes of these types of emulsion explosives are defined depending on the main components used at the final stage of their production (a blast hole or mixing and charging machine) with or without addition of dry ammonium nitrate. Diagrams of semi-stationary and mobile technological complexes have been justified for production of emulsion explosives. A rationale was provided for the selection of the competing methods to produce and deliver emulsion explosives using the case of UK Kuzbassrazrezugol JSC with account of technological and economic factors. Three competing options were considered: (1) a stationary or semi-stationary technological complex to produce emulsion explosives; (2) a stationary technological complex based on the existing plant of Nitro Siberia-Kuzbass JSC (Kemerovo) under an outsourcing agreement; (3) a mobile technological complex as a case of partial outsourcing to the Nitro Siberia-Kuzbass JSC plant. Comparison of the competing options helped to identify the third option as the priority. In this option the cost of emulsion explosives is affected by the cost of basic components at the chemical plant; depreciation of the self-propelled component delivery vehicles (10-15 vehicles); operating and maintenance costs of the delivery vehicles; rental of the mixing and charging machines (1-2 vehicles) to produce and charge the emulsion explosives. After covering the capital expenses (1-1,5 years) there will be a reduction in cost up to 20% as compared to the second option.