bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Iso 9001:2008 dalam Mengembangkan Budaya Mutu Madrasah
Authors: Fanani Moh. Zainal
Published: June 2022

The government take serious act to enhance quality of education either public or private school. One of famous way used by education organization is adopting international based quality management system. One of international based quality standard about Quality Management System is ISO 9001:2008, customer oriented quality management system. Application of Quality Management System ISO 9001:2008 in education service is the right momentum to fix quality of education especially madrasah. Application of Quality Management System ISO 9001:2008 in education organization are meant to enhance customerâ€™s satisfaction through education organization, build awareness about the urgency of prime service to customer, teach education organization so they loyal to agreeable things, and prepare quality document. The successful of Quality Management System ISO 9001:2008 implementation affected by culture own by madrasah. Sincerity is needed to facilitate and manage culture changes into quality culture.
Urgensi Penelitian Tindakan Kelas Bagi Peningkatan Profesionalitas Guru Antara Cita Dan Fakta
Authors: Ni’mah Zetty Azizatun
Published: June 2022

Professional teachers are required to have special skills and expertise in the field of teacher training in pedagogy, social, personal or professional competence so that the able to perform his duties and functions as a teacher. Ideality of classroom action research (PTK) as a medium to improve teacher professionalism in reality is not as expected, because there are still many problems found in the implementation of PTK for teachers. This constraint can be a lack of understanding of teachers on how to implement and write a PTK, the schedule of teachers who are so busy that had not time to do research, teachers thought that the PTK is difficult and some teachers who do not understand the benefits of the implementation of PTK for teachers, students or school institutions. Ideality of PTK implementation that has benefit in improving the quality of teaching and learning activities and increasing the professionalism of teachers is just a goal that is far from expectations that require solutions from various parties.
Urgensi Manajemen Peningkatan Mutu Berbasis Sekolah Di Lembaga Pendidikan Islam
Authors: Sulaeman Mubaidi
Published: June 2022

MBS is born with several different names: school-based governance, school self-management, and even school-based management. These terms do have an understanding with a slightly different emphasis. However, the names have the same spirit, ie the school is expected to become more autonomous in the implementation of school management, especially in the use of 3M its man, money, and material. The main objective is to develop school policy procedures, solve common problems, and utilize all potential individuals who are members of the team. So the school can only print people who are intelligent and emotionally high, but also can prepare the development workers. Therefore the Islamic education institution is very necessary to apply MPMBS to make the school as an integral part of society, it is not a separate institution of society, the right to life and the survival of the school depends on the community, the school is a social institution that serves to serve members of the community in education, school and community progress are mutually exclusive, both need each other.
Manajemen Qur’ani Tentang Penggunaan Waktu Dalam Bingkai Pendidikan Islam
Authors: Rohman Abdur
Published: June 2022

Humans have different fates. Among them there are already successful in their teens, when the head of three, the head of four even some who until the age of twilight remain ordinary people. Why the difference occurs, even though the time given to them is the same. The only difference is the utilization. For that, taking the best possible time becomes the key. While the Qur'an provides a way how to become a lucky person. This article uses qualitative research-literature with thematic tafsir approach that is by collecting the verses related to the theme, then interpret it. God swears by the time that success is achieved when the four components are fulfilled: faith, doing positive, counseling and being consistent on the right track and being patient. In the implementation of general education and Islamic education in particular, the issue of time management is also an important part of the success of these educational activities. There are no few signals in the Qur'an or Hadith of the Prophet (SAW) which emphasizes the importance of time management, even in the Qur'an there is a letter deliberately named with time (Al-'Arr).
Distingsi Cerai Gugat Kalangan Tenaga Kerja Wanita Desa Mrican Kecamatan Jenangan Kabupaten Ponorogo: Analisis Teori Fenomenologis Edmund Husserl
Authors: Sardjuningsih  , Thohari Ilham , Anggraini Merita
Published: June 2022

This article reveals a problematic phenomenon that befell the families of female workers (TKW) in Mrican Village, Jenangan District, Ponorogo Regency, where the legal facts of divorce (the wife filed for divorce from her husband) increased, and even became commonplace. Based on data recorded by the media from January to November; in 2020 as many as 533 divorce case decisions (203 divorced divorces and 330 divorced divorces). This condition is interesting to study, especially in terms of the reasons and factors why a TKW sues for divorce from her husband, it does not stop there, the phenomenon is analyzed using the Phenomenological theory of Edmund Husserl, a phenomenological theory that emphasizes the integration of aspects of the system and sub-systems of society. In exploring the data, the researcher used a sociological qualitative approach and Edmund Husserl's phenomenological theory by using the interview as the main instrument. In this study, the informants used as primary sources include; Mrican Village community, Plaintiffs, Defendants, and Families. The collected data is then carried out in the analysis stages starting from data display, data reduction and data verification and conclusions. The results of the study revealed that 1) the tendency of the reasons for litigation among the TKW of Mrican Village, Jenangan District, Ponorogo Regency proposed by the plaintiff was a complete and irreconcilable reason between the two parties, namely the plaintiff and the defendant. Because the reasons come from both sides themselves. The causal factors that underlie the reasons for TKW in Mrican Village, Jenangan District, Ponorogo Regency in the Phenomenological Perspective of Edmund Husserl to file for divorce are the factors causing the lawsuit (economics, environment/social/lifestyle, and personal responsibility) and supporting factors for the lawsuit (education, family and technology).
Kedudukan Antar Pesan Dakwah: Studi Ceramah Ustazah Mumpuni Handayekti Dalam Program Aksi Asia
Authors: Surya Alan , Prostyaningtyas Refita
Published: June 2022

This paper examines the position between the messages of akidah, sharia and morals in a da’wah. This paper is based on the assumption that da’wah message is the spirit of da'wah itself. Many previous research of da’wah message has found the descriptions of da’wah message in the religious lectures, both quantitatively and qualitatively, while further analysis limited to finding dominant or distinctive da'wah messages. It is still necessary to analyze the position between all kinds of da'wah messages so that Islamic teachings can be fully understood. This paper aims to examine the position of various da'wah messages such as aqidah, sharia and morals in religious lectures. So that it can be useful for preachers when composing da'wah messages before speaking it. This research is an inductive qualitative research, using three religious lectures of Ustadzah Mumpuni Handayekti in the Aksi Asia program as research objects. The result of this study are: 1) Aqidah message is the main and the basis for sharia and morals message, 2) The logical consequences for people who have faith is to obey sharia and morals teachings, 3) The position of sharia and moral messages is the same (not necessarily sequential or concurrent), 4) Ustadzah Mumpuni Handayekti has succeeded in linking various da'wah messages and packaging them well in religious lectures, 5) However, it is necessary to add the direction of the da'wah message which is not only to form a good person but also a good society, and it requires scientific and systematic teaching methods.
Peningkatan Ekonomi Masyarakat Melalui Koperasi Serba Usaha “Ribath Darul Maslahah” Di Masjid Besar Arribath Kec. Jogoroto Kabupaten Jombang
Authors: Samsuri Ali , Muttaqin Amrul
Published: June 2022

Of the several problems based on the mapping of problems carried out at the beginning of this service activity which is the cause of the inhibition of the development of the "Ribath Darul Maslahah" Cooperative, the Great Mosque of Arribath, Jogoroto District, among others, are 1. Community Perception 2. Human Resources 3. Management Management 4. Capital. However, after socialization and training, some of these problems can be resolved, although not yet fully resolved. It is proven that from the side of the cooperative members, with the cooperative training, the members can understand the existence in depth because the cooperative is related to its main finances so that members understand the credit debit and profit calculations based on the RAT each year. And the current condition of the existence of cooperatives can increase the income of the surrounding community, with a very small percentage due to the covid-19 pandemic, which has a huge impact on the economic sector and people's income. If the people's income increases, the basic savings and voluntary savings can be increased. So that the cooperative's ability to expand the business is even wider. And finally, it can further increase the income of members and the surrounding community.
Strategi Marketing UMKM Perlengkapan Pernikahan (Rona Creation) Di Desa Pacekulon Pada Masa PPKM Darurat Untuk Meningkatkan Target Penjualan
Authors: Septiana Nila Zaimatus , Firdaus Muhammad Reza
Published: June 2022

The emergence of the Covid-19 pandemic and the issuance of an emergency PPKM decree resulted in a decline in production and marketing activities for MSME actors. The purpose of this study was to find out how the Marketing Strategy of MSMEs for WeddingEquipment in Pacekulon Village During the Emergency PPKM To Increase Sales Targets. The method used in this research is using qualitative research methods. The subject of this research is MSME Wedding Equipment which is located in Pacekulon village, Nganjuk. Sources of data used in this study using primary data and secondary data. Data collection techniques in this study using interviews. This reasearch data analysis uses qualitative analysis from Miles and Hubberman. The results of this study were to deal with emergency PPKM for MSMEs for Wedding Equipment in Pacekulon village to apply online marketing strategies through social media applications such as WhatsApp, Instagram, and Facebook, although there were decreased orders for some of their products due to the pandemic and emergency PPKM.
Theoretical background to substantiation of the parameters of mixer for protein, mineral and vitamin additives
Authors: Avakimyants E. V.
Published: June 2022

One way to improve the mixing efficiency of protein-mineral-vitamin additives for cattle diets is to fluidize the material. The aim of the study is to define theoretical dependences between the speed and energy characteristics of the formation of a fluidized bed on the physical and mechanical properties of mixing substances and on structural and kinematic parameters of the mixer. The research was carried out in 2021. A coefficient of structural and mechanical resistance of the disperse many-component system was introduced to clarify the characteristics of additives mixing in the fluidization mode. The obtained equations described the particle velocity and the energy consumption for the particle flow in a fluidized bed influenced by a blade mixer. Next step was to reveal the effect of the layer porosity and the mixer blade angle on the particle velocity in the mixture. The velocity loss equation was solved as a graph for the value of 5 m/s at the blade edge. The variation in the layer porosity had a significant effect on considered parameter. The greatest velocity loss exceeded 4.5 m/s observed at the smallest porosity of 0.14 and the biggest blade angle of 75º. The smallest loss was below 0.5 m/s at the largest porosity of 0.34 and the smallest blade angle of 15º. Thus, the decrease in the particle velocity by 10 to 90 % was observed in the considered coordinates.
Boz ve Yerli Kara Irkı Sığırlarda Kalpain 1 p.Ala316Gly Genotiplerine Ait Genetik Varyasyonun Değerlendirilmesi
Authors: ARDICLI Sena , ÇOBANOĞLU Özden
Published: June 2022

Kalpain 1 (CAPN1) geni, mikromolar kalsiyum–aktive nötral proteaz geni olarak bilinir ve postmortem koşullarda miyofibriler proteinleri indirgeyen kalsiyum bağımlı sistein proteazı, μ-kalpaini ayrıştırır. Bu genin kas metabolizması ve gelişimi üzerinde önemli etkileri vardır. Bu gen, çeşitli sığır ırkları arasında geniş çapta çalışılmış olmasına rağmen, Türk yerli sığırları hakkında sınırlı bilgi bulunmaktadır. Bu nedenle bu çalışma, bazı Türk yerli sığır ırklarında CAPN1 p.Ala316Gly polimorfizmine ait genetik varyasyonu belirlemeyi amaçlamıştır. Bu kapsamda 99 Boz ve 41 Yerli Kara ırkı erkek sığır PCR-RFLP metodu kullanılarak genotiplendirilmiştir. Genotipik ve alelik frekanslar, Hardy-Weinberg dengesi (HWE), heterozigotluk (He), polimorfizm bilgi içeriği (PIC), efektif alel sayısı (Ne), fiksasyon indeksi (Fıs), olası varyasyon gerçekleşme düzeyi (%V) dahil olmak üzere popülasyon genetik parametreleri değerlendirilmiştir. Ayrıca Shannon-Weaver indeksi, Simpson dominantlık indeksi ve Gini katsayısını içeren biyoçeşitlilik indeksleri hesaplanmıştır. Sonuçlar, GG genotipinin her iki yerli ırkta da oldukça baskın olduğunu ortaya koydu. Öte yandan, toplam popülasyonda CC genotipinin bulunmadığı gözlenmiştir. Bu durum dikkate değer düzeyde düşük C allel frekansıyla sonuçlanmıştır (Boz ve Yerli Kara için sırasıyla 0.13 ve 0.12). Fisher’ın kesin testi, HWE’den sapma oldğunu, popülasyon genetiği parametreleri ise, incelenen ırklarda oldukça düşük bir genetik varyasyon düzeyi olduğunu göstermiştir. Bu gözlem, düşük seviyedeki biyolojik çeşitlilik seviyeleri ile desteklenmiştir. Nitekim CAPN1 markörü, Boz ve Yerli Kara sığırları için düşük seviyede bilgilendiricilik göstermiştir ancak Türkiye’deki yerli sığır ırklarının genetik karakterizasyonu hakkında ileride yapılacak çalışmalara ihtiyaç vardır. Yerli ırklarda yapılacak moleküler genetik çalışmalar, önemli biyolojik süreçlerle ilgili daha geniş perspektifleri ortaya koymak ve büyüme, kas gelişimi ve yem verimliliği gibi kompleks özelliklerin daha iyi anlaşılmasını sağlamak için teşvik edilmelidir.
Clases en línea y competencia digital en estudiantes taiwaneses de español durante la pandemia COVID-19
Authors: Ruiz Javier Pérez
Published: June 2022

El cierre de los centros educativos debido a la pandemia de COVID-19 obligó a proseguir la educación a través de las clases en línea en todo el mundo. Este hecho significó un hito socioeducativo sin precedentes. Ante dicha situación, se realiza estudio en estudiantes taiwaneses de español que investiga el impacto de las clases presenciales y en línea sobre su proceso de adquisición de las competencias sociolingüísticas. En segundo lugar, explora el nivel de competencia digital que dichos estudiantes perciben de ellos mismos y de sus profesores. Se utilizó una metodología cuantitativa, basada en dos cuestionarios, distribuidos una muestra de 120 estudiantes taiwaneses de español. Los principales hallazgos mostraron marcadas diferencias significativas en la valoración de ambos tipos de clase y notables carencias en la adquisición de la competencia digital en estudiantes y profesores. La relevancia de la investigación ha sido establecer una línea descriptiva de referencia, a partir de la cual poder construir futuras investigaciones experimentales.
Percepciones del profesorado sobre la implementación de AICLE en la Región de Murcia
Authors: GARCÍA ABELLÁN ANA ISABEL
Published: June 2022

Este artículo resume los resultados obtenidos de una investigación sobre la percepción del profesorado sobre diversos aspectos relacionados con la implementación del Programa Bilingüe en la Región de Murcia (España). El estudio se aborda desde tres dimensiones: lingüística, cognitiva y afectiva. La metodología que se emplea fue de corte cuantitativo a través de cuestionarios que fueron realizados por 70 profesores de Educación Primaria y analizados descriptiva e inferencialmente. Los resultados están en consonancia con los de otros estudios de percepciones similares y sugieren que existe una relación entre las creencias del profesorado y variables como la experiencia docente y la formación en AICLE.
Introduction
Authors: Madrid Fernández Daniel
Published: June 2022

Porta Linguarum issue 38 (Jun.2022)
Diseño bio-inspirado un proceso de abstracción creativa
Authors: Rossi Ludovica
Published: June 2022

El presente artículo describe un proceso de diseño bio-inspirado según la metodologiabottom-up, que inicia por la obsrevación del referente natural para sus posibles implementación a la teconología. Este enfoque tiene un paso relevante en la abstracción y conceptualización del rol biologico que permite separar el modelo biologico de su aplicación técnica.El mecanismo biologico de referencia es la estructura de madera de sosten interior de las plantas cactaceas. Se pone en relevancia la fase de la investigación que trata la construcción de modelos fisicospara la comprensión de la dinamicassubyecentes el sistema organico. Los modelos fisicosse encuentran en una fase intermedia de un proceso de diseño iterativo, que permite implementar los mecanismos biológicos más allá de la mímica directa, y poner en práctica de forma creativa los principios biológicos de adaptabilidad y crecimiento.
Life quality, anxiety and depression in patients with сhronic obstructive pulmonary disease (literature review)
Authors: Shevchenko O.S. , Kiba V.P. , Petrenko V.I. , Todoriko L.D. , Pohorielova O.O.
Published: June 2022

Chronic obstructive pulmonary disease (COPD) is an irreversible disease, the main symptoms of which are shortness of breath and cough. With progression, these symptoms worsen the patients’ life quality, limit their physical activity and lead to psychological problems. COPD is the fourth most common disease in the world and one of the leading causes of death. A review of epidemiological studies shows that depression occurs in patients with COPD in 6—80 % of cases, with an average of about 40 %. Also, these patients often have anxiety disorders in 10 to 55 % of cases.158 literature sources in Pubmed database on request COPD AND depression AND anxiety for last 10 years were included to the study and 44 of them were selected for further detailed study.According to the analysis of literature sources, possible relationships between COPD, life quality, anxiety and depressive disorders were found, approaches to their detection, monitoring and treatment were described, as well as the importance of controlling COPD symptoms to improve the patients’ life quality and reduce the manifestations of psychological and mental disorders. Evidence has been found indicating that an increase in physical activity when COPD symptoms are controlled changes the state of functioning of central monoamines, increases the regulation of the hypothalamic­-pituitary-­adrenal system, increases the release of endogenous opioids and decreases the severity of systemic inflammation, which reduces the manifestations of anxiety and depression.Due to the bidirectional relationship of patients’ life quality, depression and anxiety, and COPD, the most effective is an integrated approach that improves the patient’s condition through the impact on both physical and psychological factors. However, there is still a need for randomized trials to definitively study the benefits of psychological, pharmacological, and combined treatments for depression and anxiety disorders in COPD.
Influence of the toroidal cutter kinematics on elastic state of the machine parts surface bed
Authors: Zaides Semen , Nguyen Huu
Published: June 2022

An approach to taut state increasing within elastic-plastic deformation zone in the process of surface plastic deformation has been viewed. The technical idea of solving the problem is based on the study of workplace tool kinematics. A new hard-ening process based on the workplace tool circular oscillation is proposed. To prove the effectiveness of the new workplace tool kinematics, finite element modeling has been, which helped to determine an elastic state in the deformation zone. It is found that the oscillate rotation of the work roll is much more efficient comparing to static sliding both in the taut state and distorted condition of the hardened layer
Salud-enfermedad y cuidados odontológicos en la ruralidad: representaciones sociales de mujeres argentinas
Authors: Rubinstein Julieta , Butinof Mariana
Published: June 2022

El objetivo de este estudio fue identificar las representaciones sociales del proceso salud/enfermedad/atención desde una dimensión odontológica en pobladores rurales en el norte de Córdoba, Argentina. Se realizó una investigación de carácter cualitativo a partir del paradigma interpretativista. Se realizó observación, registrada en un cuaderno de bitácora. Se diseñó y seleccionó un muestreo intencional para la implementación de entrevistas a mujeres que asisten al hospital de Villa Candelaria Norte y efectores de salud, así como entrevistas en profundidad a una submuestra de mujeres. La información fue cargada en el Software Atlas Ti para su análisis a través de la teoría fundamentada. El proyecto fue aprobado por un Comité de Ética (Res. 384/13). Las personas entrevistadas se clasificaron en 3 grupos: a) pobladoras del centro de la localidad, b) pobladoras de parajes y c) equipo de salud. Se identifica la dimensión de análisis “proceso salud/enfermedad/atención desde una dimensión odontológica” en dos sub-categorías: a través de la percepción de dolor y la pérdida de elementos dentarios. Los resultados alcanzados ponen en evidencia que “salud” se asocia a la demanda de atención que surge ante una enfermedad bucal, reproduciendo un modelo biomédico – reparador de la enfermedad; existe una naturalización del dolor y de la pérdida de elementos dentarios. Se concluye que los resultados expuestos reflejan ausencia de una concepción de salud bucal positiva e integral que permita su cuidado desde una perspectiva preventiva. El reconocimiento de las representaciones sociales de la salud orienta la construcción de conocimientos sobre salud y enfermedad bucal.
Evaluación de la calidad de aguas superficiales en espacios recreacionales, una propuesta integradora de marcadores químicos y microbiológicos
Authors: Pavan Jorge Victorio , Masachessi Gisella , Prez Verónica Emilse , Di Cola Guadalupe , Re Viviana Elizabeth , Nates Silvia Viviana
Published: June 2022

El cambio climático afecta a las interacciones entre los sistemas hídricos, los ecosistemas y la atmósfera. También aumenta el riesgo de la presencia de microorganismos que afectan a los sistemas que utilizan estos recursos. El impacto de la población sobre los recursos hídricos se ha hecho más evidente en los últimos años, destacando la estrecha relación entre los niveles de componentes inorgánicos así como la contaminación microbiológica del agua y la salud de la comunidad. La caracterización de las variables que dan cuenta de la contaminación del agua es un proceso complejo. En este trabajo se propone la cuantificación de nitritos y fósforo como marcadores químicos y la detección de coliformes fecales, adenovirus humanos genómicos y/o picobirnavirus y enterovirus humanos infecciosos como marcadores microbiológicos para la prevención de infecciones de origen hídrico en individuos expuestos a matrices acuosas superficiales por actividades recreativas.
MicroRNA Regulation of Bone Marrow Mesenchymal Stem Cells in the Development of Osteoporosis in Obesity
Authors: Vulf Maria , Khlusov Igor , Yurova Kristina , Todosenko Natalia , Komar Alexandra , Kozlov Ivan , Malashchenko Vladimir , Shunkina Daria , Khaziakhmatova Olga , Litvinova Larisa
Published: June 2022

Obesity and osteoporosis are global health problems characterized by high rates of prevalence and mortality due to complications. As people with visceral obesity age, the adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) increases, and adipocytes become the predominant stromal cells in the bone marrow microenvironment, which hinders the physiological regeneration and mineralization of bone tissue. Primary and secondary osteoporosis remain severe progressive diseases. Both osteoporosis and obesity are associated with microRNAs (miRNAs) that induce adipogenesis and osteoresorption. This review presents analyses of the roles and clinical potential of miRNAs in the epigenetic control of BMSC differentiation and the formation and function of osteoclasts in osteoporosis with and without obesity. Understanding the fine-tuned regulation of the expression of genes critical for the balance of osteogenesis/osteolysis processes may provide hope for the development of effective and safe osteoporosis therapies in the future.
Using Regularized Multi-Task Learning for Schizophrenia MRI Data Classification
Authors: Wang Yu , Shi Jiantong , Xiao Hongbing
Published: June 2022

Background: Machine learning techniques and magnetic resonance imaging methods have been widely used in computer-aided diagnosis and prognosis of severe brain diseases such as schizophrenia, Alzheimer, etc. Methods: In this paper, a regularized multi-task learning method for schizophrenia classification is proposed, and three MRI datasets of schizophrenia, collected from different data centers, are investigated. Firstly, slice extraction is used in image preprocessing. Then texture features of gray-level co-occurrence matrices are extracted from the above processed images. Finally, a p-norm regularized multi-task learning method is proposed to simultaneously learn the site-specific and site-shared features of the multi-site data, which can effectively discriminate schizophrenia patients from normal controls. Results: The classification error rate on 10 datasets can be reduced from 10% to 30%. Conclusions: The proposed method obtains excellent results and provides objective evidence for clinical diagnosis and treatment of schizophrenia.
Percutaneous Tricuspid Valve Repair
Authors: Mangieri Antonio , Sticchi Alessandro , Gohar Aisha , Regazzoli Damiano , Fazzari Fabio , Pini Daniela , Pellegrino Marta , Pagliaro Beniamino , Loiacono Ferdinando , Chiarito Mauro , Reimers Bernhard , Praz Fabien , Latib Azeem , Colombo Antonio
Published: June 2022

Tricuspid regurgitation (TR) negatively affects patient outcomes. Surgical tricuspid valve repair/replacement carries a high operative risk and is not a viable option for many high-risk patients. Percutaneous approaches provide an attractive alternative solution for such patients since they represent a valid alternative to open heart surgery without the significant risks carried by surgery. A number of percutaneous devices are currently under clinical development. This review will discuss about the latest development in the field of percutaneous tricuspid valve repair with possible future developments.
Serum Uric Acid and Hyperuricemia Associate with Coronary Artery Disease among Postmenopausal Women
Authors: Guo Qianyun , Liu Yang , Feng Xunxun , Yang Jiaqi , Zhai Guangyao , Zhou Yujie
Published: June 2022

Background: Serum uric acid (SUA) levels has been considered a possible risk factor for coronary artery disease (CAD) for many years. Since SUA levels are greatly affected by medications, diet, and metabolism, the association between SUA and CAD has been controversial for centuries. While, the state of hyperuricemia (HUA) has been proven to have a negative impact on CAD in previous studies, there are still few clinical and epidemiological studies of HUA in CAD. In particular, evidence of this association is limited in postmenopausal women. This study explored the influence of SUA levels and HUA on CAD in this demographic group. Methods: In total, 5435 postmenopausal women were allocated to either a non-CAD group (n = 2021) or a CAD group (n = 3414). Regression analyses, including generalized linear models (GLM), correlation analysis, comparison between stratified groups, and analysis by use of diuretics were carried out on data obtained in this study. Results: SUA and HUA were found to associate significantly with CAD by univariate logistic regression analysis. In addition, GLM showed nonlinear response of CAD probability with increasing level of SUA. In multivariate analysis, we found that SUA and HUA were independently related to CAD. Correlation analysis showed that SUA and HUA both correlated positively with CAD (p < 0.001). By comparing the stratified age groups, we found that the differences among the age groups were significant (p < 0.05). Conclusions: SUA and HUA were shown to be independently associated with CAD among postmenopausal women.
Application and Measurement Properties of the Talk Test in Cardiopulmonary Patients: A Systematic Review
Authors: Vieira Ariany Marques , Martins Edgar Manoel , Althoff Amanda , Rech Daiana Aparecida , Ribeiro Gustavo dos Santos , Matte Darlan Laurício , Karsten Marlus
Published: June 2022

Background: The talk test (TT) evaluates the exercise intensity by measuring speech comfort level during aerobic exercise. There are several application protocols available to assess individuals with cardiopulmonary diseases. However, the measurement properties of the TT were not systematically reviewed yet. Methods: A systematic review was developed, registered (CRD420181068930), and reported according to PRISMA Statement. Randomized clinical trials, cross-sectional studies, or series cases were identified through multiple databases and were selected if they presented concomitant speech provocation and an exercise test. Included studies were evaluated based on methodological quality (adapted New Castle-Ottawa Scale), descriptive quality (STROBE Statement), and risk of bias (COSMIN bias risk scale). Results: Ten studies were included. Seven studies presented moderate to high quality and the majority presented good scores according to the STROBE statement. Four hundred and fourteen subjects performed the TT, the majority being patients with coronary artery disease. The test validity was supported by the included studies. Talk Test reliability was considered satisfactory, although only one study presented an adequate reliability analysis. The studies found a correlation between the last positive stage of the TT with the first ventilatory threshold. Workload, oxygen uptake, and heart rate in the last positive stage of the TT were not different from the same parameters related to the first ventilatory threshold. Conclusions: The evidence indicates that the TT is suitable as an alternative tool for the assessment and prescription of exercise in individuals with cardiovascular diseases. The stage when the individual is still able to speak comfortably is suggested as the intensity for aerobic exercise prescription. As there is still no well-defined and fully explored TT protocol, caution is required when interpreting the TT results.
Mechanisms of Myocardial Ischemia in Cancer Patients: A State-of-the-Art Review of Obstructive Versus Non-Obstructive Causes
Authors: Balanescu Dinu V. , Bloomingdale Richard , Donisan Teodora , Yang Eric H. , Parwani Purvi , Iliescu Cezar , Herrmann Joerg , Hanson Ivan
Published: June 2022

In patients with cancer, myocardial infarction (MI) has distinct features and mechanisms compared to the non-oncology population. Triggers of myocardial ischemia specific to the oncology population have been increasingly identified. Coronary plaque disruption, coronary vasospasm, coronary microvascular dysfunction, spontaneous coronary artery dissection, and coronary oxygen supply-demand mismatch are all causes of MI that have been shown to have specific triggers related to either the treatments or complications of cancer. MI can occur in the presence or absence of atherosclerotic coronary artery disease (CAD). MI with nonobstructive CAD (MINOCA) is a heterogeneous syndrome that has distinct pathophysiology and different epidemiology from MI with significant CAD (MI-CAD). Recognition and differentiation of MI-CAD and MINOCA is essential in the oncology population, due to unique etiology and impact on diagnosis, management, and overall outcomes. There are currently no reports in the literature concerning MINOCA as a unified syndrome in oncology patients. The purpose of this review is to analyze the literature for studies related to known triggers of myocardial ischemia in cancer patients, with a focus on MINOCA. We propose that certain cancer treatments can induce MINOCA-like states, and further research is warranted to investigate mechanisms that may be unique to certain cancer states and types of treatment.
Sacubitril/valsartan in Heart Failure and Beyond—From Molecular Mechanisms to Clinical Relevance
Authors: Nikolic Maja , Srejovic Ivan , Jovic Jovana Joksimovic , Sretenovic Jasmina , Jeremic Jovana , Cekerevac Ivan , Simovic Stefan , Djokovic Danijela , Muric Nemanja , Stojic Vladislava , Bolevich Stefani , Bolevich Sergey , Jakovljevic Vladimir
Published: June 2022

As the ultimate pathophysiological event, heart failure (HF) may arise from various cardiovascular (CV) conditions, including sustained pressure/volume overload of the left ventricle, myocardial infarction or ischemia, and cardiomyopathies. Sacubitril/valsartan (S/V; formerly termed as LCZ696), a first-in-class angiotensin receptor/neprilysin inhibitor, brought a significant shift in the management of HF with reduced ejection fraction by modulating both renin-angiotensin-aldosterone system (angiotensin II type I receptor blockage by valsartan) and natriuretic peptide system (neprilysin inhibition by sacubitril) pathways. Besides, the efficacy of S/V has been also investigated in the setting of other CV pathologies which are during their pathophysiological course and progression deeply interrelated with HF. However, its mechanism of action is not entirely clarified, suggesting other off-target benefits contributing to its cardioprotection. In this review article our goal was to highlight up-to-date clinical and experimental evidence on S/V cardioprotective effects, as well as most discussed molecular mechanisms achieved by this dual-acting compound. Although S/V was extensively investigated in HF patients, additional large studies are needed to elucidate its effects in the setting of other CV conditions. Furthermore, with its antiinflamatory potential, this agent should be investigated in animal models of inflammatory heart diseases, such as myocarditis, while it may possibly improve cardiac dysfunction as well as inflammatory response in this pathophysiological setting. Also, discovering other signalling pathways affected by S/V should be of particular interest for basic researches, while it can provide additional understanding of its cardioprotective mechanisms.
Pajak Pertambahan Nilai Final: Belajar Dari Ghana Dan China
Authors: Putri Dian Hasbiah , Wijaya Suparna
Published: June 2022

Penerapan PPN final Indonesia masih menjadi perdebatan berbagai pihak. Sebelum PPN final diberlakukan di Indonesia, China dan Ghana telah memberlakukan PPN skema khusus yang memiliki tujuan serupa dengan PPN final yaitu mengenakan PPN pada sektor kecil. Tujuan penelitan ini adalah mengetahui mekanisme pengenaan PPN final China, dan Ghana serta pendapat beberapa pihak terkait penerapan PPN final di Indonesia. Tulisan ini juga bertujuan untuk mengetahui perbedaan dari ketiga mekanisme yang diterapkan oleh tiap negara. Metode penelitian yang digunakan adalah studi literatur dan wawancara. Wawancara dilakukan dengan beberapa pihak terkait yaitu subdirektorat peraturan PPN Industri selaku pembuat peraturan, dosen Politeknik Keuangan Negara STAN dan dosen Universitas Indonesia selaku akademisi, dan Center for Indonesia Taxation Analysis selaku praktisi. Mekanisme yang diberlakukan pada tiap negara memiliki perbedaan. Mulai dari penamaan, tarif yang diberlakukan, cara penghitungan tarif, threshold, penetapan pemungut, subjek pajak, dan faktur pajak yang digunakan. Pengenaan dan mekanisme PPN di negara China, Ghana, dan Indonesia tentu saja memiliki perbedaan. Hal ini dilakukan untuk penyesuaian dengan kondisi wajib pajak sektor kecil, kondisi ekonomi, kondisi politik, kondisi sosial dan budaya, tujuan yang ingin dicapai, prinsip, dan faktor-faktor lainnya.
Fusariumand Allied Fusarioid Taxa (FUSA). 1
Authors: Crous P.W. , Sandoval-Denis M. , Costa M.M. , Groenewald J.Z. , van Iperen A.L. , Starink-Willemse M. , Hernández-Restrepo M. , Kandemir H. , Ulaszewski B. , de Boer W. , Abdel-Azeem A.M. , Abdollahzadeh J. , Akulov A. , Bakhshi M. , Bezerra J.D.P. , Bhunjun C.S. , Câmara M.P.S. , Chaverri P. , Vieira W.A.S. , Decock C.A. , Gaya E. , Gené J. , Guarro J. , Gramaje D. , Grube M. , Gupta V.K. , Guarnaccia V. , Hill R. , Hirooka Y. , Hyde K.D. , Jayawardena R.S. , Jeewon R. , Jurjević Ž. , Korsten L. , Lamprecht S.C. , Lombard L. , Maharachchikumbura S.S.N. , Polizzi G. , Rajeshkumar K.C. , Salgado-Salazar C. , Shang Q.J. , Shivas R.G. , Summerbell R.C. , Sun G.Y. , Swart W.J. , Tan Y.P. , Vizzini A. , Xia J.W. , Zare R. , González C.D. , Iturriaga T. , Savary O. , Coton M. , Coton E. , Jany J.L. , Liu C. , Zeng Z.Q. , Zhuang W.Y. , Yu Z.H. , Thines M.
Published: June 2022

SevenFusariumspecies complexes are treated, namelyF. aywertespecies complex (FASC) (two species),F. buharicumspecies complex (FBSC) (five species),F. burgessiispecies complex (FBURSC) (three species),F. camptocerasspecies complex (FCAMSC) (three species),F. chlamydosporumspecies complex (FCSC) (eight species),F. citricolaspecies complex (FCCSC) (five species) and theF. concolorspecies complex (FCOSC) (four species). New species includeFusicolla elongatafrom soil (Zimbabwe), andNeocosmospora geoasparagicolafrom soil associated withAsparagus officinalis(Netherlands). New combinations includeNeocosmospora akasia, N. awan, N. drepaniformis, N. duplosperma, N. geoasparagicola, N. mekan, N. papillata, N. variasiandN. warna.Newly validated taxa includeLonginectria gen. nov.,L. lagenoides,L. verticilliforme,Fusicolla gigasandFusicolla guangxiensis. Furthermore,Fusarium rosicolais reduced to synonymy underN. brevis.Finally, the genome assemblies ofFusarium secorum(CBS 175.32), Microcera coccophila(CBS 310.34),Rectifusarium robinianum(CBS 430.91),Rugonectria rugulosa(CBS 126565), andThelonectria blattea(CBS 952.68) are also announced here.
KOPERASI SYARIAH & UMKM “HUBUNGAN PEMERINTAH DENGAN GERAKAN KOPERASI”
Authors: H Yuris Huswatun
Published: June 2022

Koperasi memiliki peran yang begitu sentral dalam perekonomian nasional, karena kehadirannya sebagai suatu usaha bersama untuk memperbaiki keadaan kehidupan ekonomi berdasarkan tolong menolong, dinilai memiliki kesamaan dengan sistem sosial bangsa Indonesia, yaitu gotong royong. Dari kesamaan itulah lahir kesadaran akan makna demokrasi ekonomi yang lalu melahirkan landasan perekonomian nasional sebagaimana terdapat dalam Pasal 33 Undang – Undang Dasar Negara Republik Indonesia Tahun 1945 (UUD 1945).2 Pasal 33 ayat (1) UUD 1945 menyebutkan bahwa perekonomian disusun sebagai usaha bersama berdasarkan atas asas kekeluargaan. Keterangan mengenai landasan perekonomian nasional lebih dipertegas dalam penjelasan Pasal 33 sebelum ditetapkannya Perubahan Keempat UUD 1945 yang menyebutkan bahwa perekonomian disusun sebagai usaha bersama berdasar atas asas kekeluargaan, dan bangun perusahaan yang sesuai dengan itu ialah Koperasi.Artinya, koperasi tidak hanya diakui sebagai bentuk perusahaan yang ideal, tetapi sekaligus ditetapkan sebagai model mikro sistem perekonomian nasional yang hendak dibangun, yaitu sistem perkonomian berdasarkan atas asas kekeluargaan.Kedudukan koperasi di dalam sistem perekonomian nasional dapat dikatakan sebagai sokoguru perekonomian, artinya kegiatan ekonomi rakyat di bawah yang mendukung perekonomian di atasnya dalam hubungan vertikal.Dengan kata lain koperasi merupakan tulang punggung dari sistem perekonomian nasional dalam meningkatkan kesejahteraan masyarakat
What Is Customer Profile ?
Authors: Maheswara Benaya Alto Yonata , Wirahmaja Michael Jonathan , Adelina Pavita Rania
Published: June 2022

Menggambarkan siapa yang menjadi segmen pelanggan dalam model bisnis, secara lebih terstruktur dan terperinci, dengan mencari tahu Customer Profile pada tahapan Business Model Canvas (BMC).
STRATEGI PENGEMBANGAN KOPERASI DAN UMKM
Authors: Ifhadiyanti Nurul
Published: June 2022

berbagai kebijakan yang dibuat akan menyimpang dari harapan dan pada akhirnya tidak akan memberikan manfaat kepada kelompok ekonomi yang bergerak pada sektor ini. Pengalaman di berbagai tempat menunjukkan, tidak sedikit kebijakan yang dibuat pada akhirnya tidak memberikan manfaat dan bahkan menambah beban UMKM
Business Model Design Process
Authors: Christianto Billiam Steven
Published: June 2022

Business Model Design adalah tahapan yang perlu dilakukan saat membuat Business Model.
Koperasi dan Usaha Lainnya (Siti Nurfadhilah 90500120063)
Authors: nurfadhilah
Published: June 2022

Makalah tentang apa itu Koperasi dan Usaha Lainnya
METHODS OF MAINTAINING THE MEMORIZATION OF THE QURAN OF HAFIDZ HAFIDHOH STUDENTS THROUGH JHQ-IAIN PEKALONGAN
Authors: Suhandi Ikbal
Published: June 2022

The Qur'an is a holy book that is a guide for Muslims, so it is our obligation as Muslims to guard it, one of which is by keeping it by memorizing it. Memorizing the Qur'an is also not easy, and of course, it must also be thought about before doing it. Especially for students who are still in the process of memorizing or who have memorized it, it will be difficult to divide the time if there is no seriousness in maintaining it. And of course, there is a need for a special container or jamiyyah for memorizing the Qur'an, so the article will explain the method of maintaining the memorization of the Qur'an by Hafidz Hafidhoh students through JHQ Iain Pekalongan activities with the aim that Hafidz Hafidhoh students at IAIN Pekalongan are still memorized., the association, or the conversation when busy with college assignments and activities outside campus.
Christian Mission, Spiritual Leadership and Personality Development of the Digital Generation
Authors: Paat Vicky BGD
Published: June 2022

Spiritual leadership has experienced a significant correction of service responsibilities for God's church. Several reasons are advances in information technology, social media, and financial problems. On the other hand, the digital generation is the majority of the congregation. The facts show that 6 out of 10 people (59%) leave the Christian faith in the first decade of adulthood, and the number 44% - 52% do not go to church. The personality of the digital generation tends to be eroded, while the church leadership seems to have lost the enthusiasm to reach them. The question is how to build the resilience of spiritual leaders in the digital age? What kind of implications and approaches in developing the personality of the Digital Generation can take? The purpose is to describe the steps to build spiritual leadership resilience and explain the implications and mission approaches of digital generation personality development. Research is a qualitative descriptive method. The results are building Spiritual Leadership Resilience by upgrading oneself in contemporary leadership, building friendships, synergizing with other spiritual practitioners, and building worship praise as a medium for spiritual experience. The implications for the digital generation are: Developing the three vocations of the church, building intergenerational relationships and leadership spirit, generating gifts and role effectiveness, and emphasizing the meaning and fulfillment of future leadership functions.
BERPIKIR KREATIF DAN MENERAPKAN MANAJEMEN PEMASARAN BANK SYARIAH
Authors: Azifah Nurul
Published: June 2022

Pemasaran merupakan suatu proses perencaan dan menjalankan, harga,promosi dan distribusi sejumlah ide, barang dan jasa untuk menciptakan pertukaran yang mampu memuaskan individu dan organisasi.
SISTEM OPERASIONAL INTERNAL BANK SYARIAH
Authors: khasanah uswatun
Published: June 2022

Eksistensi perbankan syariah yang kini semakin berkembang pesat telah menjadi sebuah indikator dari keberhasilan ekonomi Syariah di Indonesia. Sistem ekonomi syariah mempunyai aturan yang dilandaskan berdasarkan prinsip hukum Islam, dimana prinsip tersebut mengharamkan adanya sistem riba, sebagaimana yang telah ditetapkan dalam ayat- ayat yang terkandung dalam al-Quran.Prinsip Islam yang diwujudkan dalam kegiatan ekonomi tersebut merupakan sebuah keniscayaan dari kesempurnaan agama Islam itu sendiri yang kebaikannya bukan hanya dapat dirasakan bagi masyarakat muslim saja namun juga akan memberikan kebaikan bagi seluruh umat. Melihat begitu banyak kebaikan yang akan didapat, bank syariah yang merupakan implemensi dari sistem ekonomi Islam seharusnya menjadi prioritas utama baik bagi masyarakat muslim maupun non muslim dalam memberikan amanah sebagaimana fungsinya sebagai lembaga intermediasi, dimana inti dari fungsi bank sebagai lembaga intermediasi adalah menghimpun dana dari masyarakat yang kelebihan dana untuk kemudian disalurkan kembali kepada masyarakat yang membutuhkan dana melalui pembiayaan serta memberikan pelayanan produk jasa dan sosial. Selain fungsi dari bank seperti penjelasan tersebut, juga perludipahami bahwa pengertian bank syariah itu sendiri merupakan lembaga keuangan bank yang berdasarkan prinsip syariah. Prinsip syariah dalam hal ini adalah aturan perjanjian yang berdasarkan hukum Islam antara bank dan pihak lain untuk penyimpanan dana atau pembiayaan usaha atau kegiatan lainnya yang dinyatakan sesuai dengan syariah
Renal morphophysiology is not a significant correlate of observable body condition in Masked Palm Civets (Paguma larvata)
Authors: Lê Nhung , Hoang Thuy , Tran Truong , Tran Trieu , Van Nguyen Thai , Van Hoang Thai , Gray Russell J.
Published: June 2022

BackgroundViverrid species such as Masked Palm Civets (Paguma larvata) are commonly hunted and widely trafficked in Southeast Asia. Anti-poaching and anti-trafficking efforts to intercept trafficked animals are increasing in countries where the wild meat trade is dominant, such as Vietnam, due to concerns of potential animal-human disease transfer which may have caused the Covid-19 pandemic. MethodsThis study aimed to create a baseline of renal morphology for P. larvata using data collected from 91 individuals seized from wildlife traffickers in Vietnam. Since body condition was also scored and examined for each animal, we explored whether or not healthy or emaciated body condition could be used as a predictor of kidney morphometrics in the species.ResultsOur results indicate that renal morphology for P larvata is not significantly sexually dimorphic, and do not significantly reflect body conditions in the species. ConclusionSince baseline data for Viverrid average renal structure is deficient, and non-existent for the species, this information can be used to evaluate the species in future seizures, rescues, and release programs to detect kidney size abnormalities and exclude body condition as an associated sign.
From outcome-based to language-based preferences
Authors: Capraro Valerio , Halpern Joseph Y , Perc Matjaz
Published: June 2022

We review the literature on models that try to explain human behavior in social interactions described by normal-form games with monetary payoffs. We start by covering social and moral preferences. We then focus on the growing body of research showing that people react to the language in which actions are described, especially when it activates moral concerns. We conclude by arguing that behavioral economics is in the midst of a paradigm shift towards language-based preferences, which will require an exploration of new models and experimental setups.