bluuebunny/crossref_metadata_2025 huggingface dataset:
Dîroka Zirkîyan û Beşdarîya Wan di Çanda Kurdî da
Authors: Ergün Zülküf
Published: November 2024

Zirkî di hezar salên dawî yên dîroka kurdan da yek ji binemaleyên giring ên kurdî ye ku di Şerefnameyê da behsa wan tê kirin. Şerefxanê Bedlîsî ji Şêx Hesenê Ezreqî ku wî bavê damezirînerê vê binemaleyê qebûl dike, heta dema xwe behsa vê binemaleya giring bike jî giranî dide ser dîroka wan a sedsala 16ê. Piştî navbereke dirêj ev mijar di van salên dawî da bala çendîn dîronknas û vekolerên nû dikêşe û Zirkî dibin mijara çendîn gotar û pirtûkan. Em bi vê xebatê hewl didin van zanyarîyên li ser Zirkîyan bi awayekî sîstematîk bixine rû, nakokî û valahîyên dîroka Zirkîyan dîyar bikin, kêşeyên wan ên navxweyî destnîşan bikin û beşdarîya wan di çanda kurdî da ron bikin. Ji ber vê em di dawîya vê xebatê da digihîjin vê encamê ku Zirkî di hezar salên dawî da çawa di berhemanîna dîroka kurdî ya sîyasî da dibin beşdarên giring, di dîroka çanda kurdî da jî dibin xwedî pêgeheke bihêz ku ji nav wan hin dîroknûs, edîb û zanayên giring derdikevin.
Arapça Edebi Metinlerde Üslup Değişimi Göstergesi Olarak Söz Sanatları Yoğunluğu: Bânet Su’âd ve Kasîde-i Bürde Örneği
Authors: İnce Nazife Nihal , Göktur Ömer
Published: November 2024

Bu çalışmada Arapça edebi metinlerde söz sanatlarının yoğunluğu bir üslup değişmi göstergesi olması yönüyle araştırılmıştır. Dil ve edebiyat çalışmlarında tartışmalı kavramlardan biri olan üslup, en genel haliyle, “içeriğin formu” olarak tanımlanır. Bu çalışma, dilsel formların başında gelen söz sanatlarını üslup göstergesi olarak ele almıştır. Farklı çağlarda yazılmış ve ortak teması bulunan iki kaside örneğinde söz sanatlarının yoğunluğu incelenmiştir. İncelenen kasideler: Bânet Su’âd ve Kasîde-i Bürde’dir. Beyân ilminin sanatlarıyla sınırlı tutulan araştırmada, araştırılan söz sanatları: teşbih, istiâre, mecâz-ı mürsel, mecâz-ı aklî ve kinâyedir. Diğer yandan kasidelerde kullanılan beyân sanatlarının tespitinde sübjektifliği minimize etmek için metin tahlili yapan üç eserden yararlanılmıştır. Çalışma, kasidelerde kullanılan beyân sanatlarının yoğunluğuna odaklandığı için tespit aşamasında birtakım tercih kriterleri belirlenmiştir. İnceleme neticesinde Bânet Su’âd kasidesinde kinâye sanatının yoğun olarak kullanıldığı, Kasîde-i Bürde’de ise İstiâre sanatının yoğun olarak kullanıldığı tespit edilmiştir. Araştırmada dikkati çeken bir başka husus ise Kasîde-i Bürde’ beyitlerinin neredeyse beşte birinde herhangi bir beyân sanatının kullanılmamasıdır. Ayrıca Bânet Su’âd kasidesinde beyân sanatları yoğunluğu daha homojen bir yapı arz etmekteyken Kasîde-i Bürde’de bazı beyitler çok yoğun beyân sanatı içerirken bazılarında herhangşi bir beyân sanatı bulunmamaktadır. Söz konusu bulguların şâirlerin özel tercihlerini yansıtma ihtimali de bulunmaktadır. Bu nedenle bulguları bir üslup değişimi olarak yorumlamak için benzer çalışmalrla desteklenmesi gerekmektedir.
Hareket’in İzleri: Nurettin Topçu’nun Erken Cumhuriyet Dönemiyle İlgili Eleştirel Görüşleri
Authors: Yetim Fahri
Published: November 2024

Türk düşünce hayatı kadim geçmişinden aldığı güçle modernleşme sürecinde de oldukça dinamik bir seyir izlemiştir. Bununla beraber modernleşme sürecine intibak konusunda farklı tezleri içeren çağdaş Türk düşüncesi içinde teorik yaklaşımlar, tahlili düşünce ve eleştirellik konusunda bazı eksiklikler söz konusudur. Büyük ölçüde tarihsel gecikmişliğin telafisine dönük kaygılardan kaynaklan bu durum, zaman içinde eleştiri ortamının giderek daralmasına yol açmıştır. Cumhuriyet dönemi itibarıyla bu açığın giderilesine yönelik adımlardan biri olan Hareket dergisi, 1939 yılında başladığı yayın hayatı boyunca Cumhuriyet tarihinde felsefi düzeyde eleştirel düşünceye öncülük etmesiyle önem taşır. Türkiye’nin ilk yurt dışı doktoralı felsefe doçenti olan Nurettin Topçu’nun girişimleriyle çıkan ve zaman içinde çoğulculuğa açık, kalabalık bir yazar grubuna ulaşan Hareket dergisi, içerdiği eleştirel metinlerle modern Türkiye’nin geçirdiği değişimin farklı açılardan değerlendirilmesine önemli katkılar sağlamıştır. Bu bakımdan Hareket dergisinin bir bütün olarak değerlendirilesinin yanında, derginin ana eksenini oluşturan Nurettin Topçu’nun özellikle ilk dönemlerde yazdığı makaleler, Türkiye’nin modernleşme tarihine alternatif bakış açıları getirebilecek bir külliyatı içerir.
Bu çalışmada, Türkiye’nin modernleşme ile geçirdiği büyük değişim konusunda özellikle erken Cumhuriyet dönemi olmak üzere yukarıda sözü edilen yaklaşımlar çerçevesinde başta Topçu olmak üzere Hareket dergisinde yer alan bazı eleştirel görüşlerin bir değerlendirilmesi yapılacaktır.
UN ESCRITOR SERBIO EN BUSCA DE ESPAÑA: LA IMAGEN DE GRANADA EN LA OBRA DE MILOŠ CRNJANSKI
Authors: Sekulić Mirjana
Published: November 2024

Siguiendo los planteamientos imagológicos, proponemos estudiar la visión de Granada y España en los relatos de viajes de Miloš Crnjanski, quien visitó España en 1933 junto con un grupo de periodistas, representantes de varios países europeos y Estados Unidos. El viaje oficial, con el motivo de dar testimonio sobre la situación social, política y cultural española durante la Segunda República, así como para promover la riqueza turística de España, dio como resultado relatos de viajes que Crnjanski publicó sobre distintos temas españoles. Entre los temas tratados destaca la búsqueda de una «verdadera» España. Analizaremos cómo este tema se relaciona con la visión de Andalucía, y Granada en especial, cuestionando ciertos estereotipos y lugares comunes que aparecen en su descripción. Entre los ejes temáticos analizaremos la música española y la impresión que dejaba en Crnjanski, el tema del paso del tiempo con respecto a la historia española, así como la pérdida de autenticidad española en base a la oposición entre lo tradicional y lo moderno en la España contemporánea. Utilizando las teorías de intertextualidad, estudiaremos el peso del bagaje cultural del autor, que, junto con las impresiones del viajero extranjero, define en buena medida la imagen que ofrece de esta ciudad.
The Evolution of Ogoh-Ogoh Performances in Fostering Religious Tolerance
Authors: Rahmadani Anisya , Prasetyo Kuncoro Bayu
Published: November 2024

The village of Linggoasri, located in Pekalongan Regency, is a village that features notable religious pluralism because its community consists of 13.02% Hindu, 86.83% Muslim, and 0.14% Buddhist. Although most of the population is Muslim, religious diversity does not hinder the recognition of the Ogoh-Ogoh tradition. Initially rooted in Hinduism, Ogoh-Ogoh has become a symbol of unity and diversity for all community members. The active participation of the community in the Ogoh-Ogoh celebration underscores the importance of this tradition as a cultural heritage recognized as belonging to all the people of Linggoasri Village. The research aims to explain the role of the Ogoh-Ogoh performance in fostering religious harmony and its impact on social integration in Linggoasri Village. Using a descriptive qualitative method, data were collected through participatory observation, interviews, and document studies. The research results show that the Ogoh-Ogoh parade plays a role in uniting the diverse religious community of Linggoasri. This event becomes a moment where all community members come together without concerning themselves with religious differences. The atmosphere of togetherness creates a point of integration that can open opportunities for interfaith dialogue and build mutual understanding among villagers, as well as being an effective medium for tolerance that teaches the values of appreciating diversity. From Bourdieu's habitus perspective, the Ogoh-Ogoh performance facilitates the formation of collective mindsets and behaviors. The active involvement of the Linggoasri community can deepen understanding of Hindu cultural values and appreciate religious diversity, thus forming an inclusive and equal society where respecting religious differences becomes a substantial value.
Comparison of Two PCR Primer Sets for In-House Validation of GHSR Gene Variation Detection Employing Artificial Recombinant Plasmid Approach
Authors: Ahsanal Kasasiah  , Jekmal Malau  , Sekar Andjung Tresnawati  , Priscinya Christiana Debora  , Nur Komala Fitri  , Saarah Hamidah Asmara Indratno  , Asman Hitopik  , Eriyanti Astika  , Anisa Aula Rahma  , Fikri Al Mukhlas
Published: November 2024

Stunting is a significant global public health problem caused by long-term dietary deficits that affect many children worldwide. Both environmental and genetic factors, including variants in the GHSR gene, play a crucial role in stunted growth. This study used an artificial recombinant plasmid DNA method to evaluate two primer set combinations for identifying DNA variants in the GHSR gene. Selecting suitable primer sets for identifying GHSR genetic variants linked to stunting is essential, as evidenced by PCR and sequencing techniques. The target gene, based on the GHSR reference sequence, consists of eight DNA variations (ΔQ36, G57G, P108L, L118L, R159R, C173R, D246A, and A277P). A recombinant plasmid was created by inserting a 1000 bp fragment of the GHSR gene into the pUC57 backbone. Primer sets were chosen based on their capacity to amplify these eight genetic variations and were optimized and validated using PCR methods. PCR and bi-directional sequencing verified the existence of surrounding DNA and specific single nucleotide variants (SNVs). In our study, we discovered four changes in the DNA sequence (R159R G>A, C173R T>C, D246A A>C, and A277P G>C) using the E1_F2/E1_R3 primer pair. Additionally, a new combination of primers (E1_F1/E1_R3) effectively detected seven DNA sequence mutations (ΔQ36 del CAG, G57G C>T, P108L C>T, L118L C>T, R159R G>A, C173R T>C, and D246A A>C). We have developed a new combination of forward and reverse primers to identify seven SNVs in the GHSR gene, which could serve as a diagnostic tool in clinical laboratory settings.
First Record of Milk thistle (Silybum marianum, Asteraceae) as Invasive Weed Species in Urban Green Areas of Addis Ababa City, Ethiopia
Authors: Kassie Weldesenbet Beze
Published: November 2024

With increasing globalization and trade, the rate of invasive species entering and spreading has significantly increased globally. These include various invasive insect pests, pathogens, and weeds. Since three years ago, Milk thistle, Silybum marianum, an invasive weed species, has been observed widely in urban green spaces and roadsides in Addis Ababa city, Ethiopia. Weed surveys were conducted across 42 urban green sites located in Yeka, Lemi Kura, Bole, Nifas Silk-Lafto, Kolfie Keraniyo, Akaky Kality, and Gullele sub-cities during the main rainy season from June to September 2023, with the main objective of determining the current distribution of the weed in Addis Ababa city. The urban green areas were selected by using purposive sampling techniques. Field observations confirmed that Silybum marianum can invade and colonize wide habitats and is a highly competitive invasive weed to other important native plant species. High weed density rates and dense stands of weeds were recorded in the 34 urban green areas sampled. The survey result strongly suggests fast integrated weed management options such as mowing/tilling, weeding before the plant goes to seed, cutting (stems and/or seed heads), and burning (collected plant parts and/or seed heads) into a prepared burrow were done to minimize the spreading of the weed and its ecological impacts. The purpose of this survey study is to provide information about Silybum marianum to minimize or avoid its distribution and associated impacts by following sustainable invasive weed management programs in the city before spreading to other cities in the country.
Synthesis and Characterization of Edible Film Based on Glucomannan from Local Porang Tubers with a Combination of Carrageenan and Sorbitol as Plasticizer
Authors: Afriyani Hapin , Herasari Dian , Amrulloh Hanif , Faranida Qori Hikmah , Ramadani Arip , Afifah Nida Rafa , Indriani Marcella , Theledi Karim , Aluko Olukemi
Published: November 2024

In this study, edible films were made from glucomannan from local porang tubers, carrageenan, and sorbitol as the plasticizer. This research method begins with the making of modified porang flour with three immersion treatments, namely control (A), 10% lime solution (B), and modified lime and mocaf starter fermentation (C) to reduce oxalate levels. Plasticizers were added with variations of carrageenan 2;3;4%, and sorbitol 1;2;3;4; and 5 g. The results showed that the modified lime immersion and fermentation treatment reduced calcium oxalate levels, and the highest yields of glucomannan were 2.58% and 10.07 g. The FTIR analysis results of the isolated glucomannan showed that the spectrum formed by the presence of O-H functional groups, CH2 groups, C-O-C groups, absorption areas of 805 cm-1 and 872 cm-1 indicated the presence of the main constituent of glucomannan, namely β-pyranose. In comparison, the characteristics of the edible film obtained an average thickness between 0.32–1.50 mm. The highest thickness was obtained in the composition of the addition of 3% carrageenan and 4 grams of sorbitol variation C. The percentage of water resistance of edible film variations A and C ranged from 10.04% - 22.02%. Variations A and C with a composition of 2% carrageenan and 1 gram of sorbitol, the edible film is completely degraded. The surface morphology of the edible film obtained from variation A with a concentration of 2% carrageenan and 5 grams of sorbitol showed a slightly porous surface.
Contrefil à rythme annuel dans les Faro, Daniellia sp. pl.
Authors: Détienne Pierre
Published: November 2024

Des variations constantes de l'angle du grain ont été observées dans l'ensemble des espèces de Faro, et en particulier dans les échantillons à grain droit. Il s'agit d'un grain imbriqué au sens strict, mais de très faible ampleur ; sa particularité est qu'il a une périodicité annuelle. Il est causé par des réarrangements perpétuels entre les cellules cambiales d'un étage par rapport aux cellules des étages adjacents.
Rola związków zawodowych w tworzeniu i stosowaniu prawa przy zwolnieniach grupowych
Authors: Latos-Miłkowska Monika
Published: November 2024

Zakładowe organizacje związkowe odgrywają istotną prawotwórczą rolę w procedurze zwolnień grupowych jako podmioty uprawnione do zawierania porozumień w sprawie zwolnień grupowych. Autorka niniejszego artykułu stawia jednak tezę, że w orzecznictwie Sądu Najwyższego doszło do nieuprawnionego ograniczenia prawotwórczej roli związków zawodowych w sytuacji, gdy zwolnienia grupowe przybierają postać programów dobrowolnych odejść. Konsekwencją wyeksponowania prawotwórczej roli związków zawodowych w procesie zwolnień grupowych jest ograniczenie ich roli na etapie stosowania prawa, co przejawia się zwłaszcza w zwolnieniu pracodawców z obowiązku konsultacji zamiaru wypowiedzenia. Tym samym związki zawodowe nie mają możliwości następczej kontroli stosowania porozumienia zbiorowego, które zawarły. Próby poszerzenia zakresu działania zakładowych organizacji związkowych w zakresie kontroli stosowania prawa w zwolnieniach grupowych natrafiają na istotne przeszkody, zwłaszcza na gruncie przepisów o ochronie danych osobowych.
Rola związków zawodowych w postępowaniu przed sądem pracy i ubezpieczeń społecznych
Authors: Jabłoński Andrzej
Published: November 2024

Artykuł poświęcony jest roli związków zawodowych w postępowaniu przed sądami pracy i ubezpieczeń społecznych w aspekcie ustrojowym oraz procesowym. Uprawnienia procesowe związków zawodowych obejmują możliwość wytoczenia powództwa na rzecz pracownika lub przystąpienia do sprawy po jego stronie, a także wskazanie przedstawiciela reprezentującego pracownika (ubezpieczonego) w charakterze pełnomocnika. Wskazane uprawnienia służą realizacji zadań statutowych związków zawodowych w zakresie reprezentowania i obrony praw pracowniczych w obszarze procesowego prawa pracy. Ich celem jest wsparcie pracownika w uzyskaniu sądowej ochrony jego praw.
Uwagi o roli związków zawodowych w zakresie związkowej reprezentacji praw i interesów pracowników wykonujących wolne zawody
Authors: Borowicz Jacek
Published: November 2024

Niniejszy artykuł poświęcony jest rozważaniom na temat roli związków zawodowych w reprezentacji i obronie praw i interesów zawodowych i socjalnych szczególnej grupy osób wykonujących pracę zarobkową w rozumieniu przepisów ustawy z dnia 23 maja 1991 roku o związkach zawodowych, jaką stanowią wykonawcy wolnych zawodów regulowanych pozostający w zatrudnieniu (pracowniczym i niepracowniczym — w szczególności cywilnoprawnym). W szczególności rozważane są w nim kwestie relacji pomiędzy związkiem zawodowym a samorządem zawodowym w zakresie wpływu tych podmiotów na procesy tworzenia i stosowania przepisów prawa dotyczącego tej kategorii zatrudnionych.
Państwowa Inspekcja Pracy jako gwarant prawidłowego dokumentowania pracy w szczególnych warunkach lub o szczególnym charakterze
Authors: Jabłoński Andrzej
Published: November 2024

W artykule przedstawione zostały zadania Państwowej Inspekcji Pracy (dalej: PIP) w zakresie kontroli i nadzoru nad prawidłowością realizacji przez pracodawcę obowiązku dokumentowania pracy w warunkach szczególnych lub o szczególnym charakterze. Uzasadnieniem dla podjęcia tego tematu są zmiany legislacyjne, które nastąpiły z dniem 1 stycznia 2023 roku. W ich wyniku Inspekcja otrzymała uprawnienie do kontroli merytorycznej tej dokumentacji. Ważnym celem artykułu jest odpowiedź na pytanie, czy nakaz wydawany przez PIP wiąże organy rentowe oraz sąd w zakresie ustalenia, czy praca była wykonywana w warunkach szczególnych lub o szczególnym charakterze.
Configurations of entrepreneurial ecosystems
Authors: Inácio Júnior Edmundo , Gimenez Fernando Antonio Prado , Stefenon Rafael
Published: November 2024

Entrepreneurial ecosystems (EEs) are receiving greater attention both in the academic world and in the field of government action. Recently, many studies have used a configuration perspective in the analysis of EEs. However, many of these studies have not specifically addressed whether different EE configurations can produce similar outputs; that is, they do not properly explore the concept of equifinality. Our main purpose was to fill this theoretical and empirical gap by exploring and demonstrating the patterns of performance of EEs (e.g., configurations) along a bundle of entrepreneurial outcome indicators. Using the Entrepreneurship Framework Conditions (EFCs) indicators provided by the Global Entrepreneurship Monitor (GEM) from 60 countries and applying exploratory factor analysis and cluster analysis, we identified and developed five distinctive EE configurations. Later, by applying analysis of variance (ANOVA) to compare these EE configurations across the entrepreneurial outcome indicators, we were able to show distinctive (dis)similarities with respect to the outcome indicators investigated. The results contribute to the understanding that there is not only one type of successful EE. In other words, the equifinality of EEs was empirically evidenced by our analysis. This is a significant theoretical contribution to the field, emphasizing the need for a broader view of how EEs may be configured and denying the relevance of searching for an ideal EE.
Recent progress of hydrogels in brain-machine interface
Authors: Zhang Mingxuan , Hao Mingming , Liu Botao , Chen Jianping , Ren Guoqiang , Zhao Yinchao , Guo Jinxiu , Zhuang Liping , Zhao Shunying , Peng Zhaoxiang , Lian Jiangfang , Wu Jingjin , Chen Yi , Ma Jingyun , Lu Qifeng
Published: November 2024

The long-term stable monitoring of brain signals, including electroencephalogram (EEG), electrocorticogram (ECoG) and local field potential (LFP), is of great significance for the fundamental research in brain science, artificial intelligence and the diagnosis and treatment of brain-related disorders. Therefore, both non-invasive and invasive brain-machine interfaces based on different materials and structures have been widely studied due to their unique performance. Among these materials, hydrogels have emerged as a promising interface material for brain signal collection systems due to their similar mechanical properties to biological tissues, excellent biocompatibility, strong self-adhesive properties, and exceptional ionic conductive characteristics. This review aims to provide an overview on the recent progress of hydrogel-based brain interfaces in the recording of brain signals with non-invasive and invasive methods. It is expected that this paper will serve as a valuable summary and reference for future research in the hydrogel-based brain interface.
Use of a fluorescent molecular rotor probe for nanoplastics assessment in epiphytic biofilms growing on submerged vegetation of Lake Saint Pierre (St. Lawrence River)
Authors: Mouatchô Linsey Yvette , Roubeau Dumont Eva , Ponton Dominic E. , Gagné François , Amyot Marc , Lavoie Isabelle
Published: November 2024

Studies on plastic pollution conducted in freshwaters mainly focused on monitoring plastic debris in the water column or in the sediments. Few studies have investigated the occurrence of plastic debris in benthic biofilms (periphyton). Yet, algal biofilms may potentially act as a sink for plastic debris, trapping it within their mucilaginous or filamentous matrix. Biofilms may also represent a source of plastic debris by sloughing when they become senescent. In addition, plastic debris accumulated within biofilms may enter the food web via primary consumers. Considering these observations, this study aims to quantify nanoplastics (NPs) accumulated in biofilms growing on aquatic vegetation from Lake Saint Pierre (LSP), a fluvial lake of the St. Lawrence River, and its archipelago. Biofilms were removed from submerged plants and the presence of NPs was assessed by spectrophotometry using the fluorescent molecular rotor probe 9(dicyanovinyl)-julolidine (DCVJ). The results of this study confirm the biofilms’ ability to act as a sink for NPs. Despite the fact that the determination of the absolute nanoparticle number and size distribution remains a challenge, we estimated a median concentration of 1.05 × 109 NP/mg of biofilm dry weight (DW) when using 100 nm polystyrene beads for calibration. Concentrations were significantly different between water masses, with higher concentrations in samples collected in the two lateral water masses compared to the central water mass. Our study provides, for the first time, a quantitative assessment of NPs from epiphytic biofilms in a large river under the influence of anthropogenic sources.
Equine-Facilitated Psychotherapy (EFP) and Well-Being: Exploring the Experiences of UK Military Veterans Using a Dialogical Narrative Approach
Authors: Campbell Imogen , Murphy David
Published: November 2024

Despite experiencing high rates of mental health and social difficulties, veterans face a range of internal and external barriers to accessing psychological therapy. Equine-facilitated psychotherapy (EFP) is a relatively new intervention, which a growing evidence base suggests can be effective, particularly for those who find it difficult to engage in traditional psychotherapies. EFP is underpinned by principles of psychodynamic psychotherapy, as well as theories regarding attachment, biophilia, and social support. Research on EFP with veterans is limited, with only a handful of studies, almost all of which have been conducted in North America. This first UK study explores veterans’ narratives of mental health difficulties and their experiences of EFP, using well-being to frame the shared experiences. Interviews were conducted with five veterans (three female, two male) who had received EFP. The analytical approach employed was dialogical narrative analysis. Themes identified across participant stories included relating to the horse, insight, self-regulation, focus of attention, a safe environment, personal relatedness, and empowerment. Dialogical questions elucidated how aspects of the veteran identity and cultural narratives contributed to the stories chosen.
The findings provide significant insight into the EFP experiences of veterans, which were resoundingly positive. Well-being may be improved through the development of meaningful relationships with horses, facilitators, and peers, adaptive coping mechanisms, and a renewed sense of self and optimism. Future research directions are suggested, and clinical implications such as the impact of the environment, as well as the role of peer support for veterans’ mental health services, are considered.
Sequence stratigraphic framework of carbonates in mixed siliciclastic–carbonate sequences: local versus external controls in a tectonically active basin (Lorca Basin, Miocene, SE Spain)
Authors: Carpentier Cédric , Vennin Emmanuelle , Olivier Nicolas , Martin-Garin Bertrand
Published: November 2024

The sequence stratigraphic framework of initiation and growth of carbonates in environments impacted by siliciclastic inputs is highly variable because of the biogenic nature of the sedimentary production and its sensitivity to environmental conditions. Using panorama interpretations, logging, and characterization of benthic communities, the mixed carbonate–siliciclastic sedimentary succession of the Neogene Lorca Basin (SE Spain) has been studied to decipher the role of local and global controlling parameters on the sequence stratigraphic framework of carbonate production. Three different carbonate depositional models are distinguished: 1) retrogradational homoclinal ramps (type 1) dominated by heterozoan communities that developed lateral to alluvial fans, 2) progradational flat-topped coral platforms (type 2) with Porites and Tarbellastraea coral carpets with a coeval retrogradational pattern on basin margins, and 3) retrogradational narrow siliciclastic-rich coral platforms (type 3) with Tarbellastraea buildups intercalated with deltaic deposits. Onset of carbonate production systematically occurred during transgressions controlled by eustasy and was locally enhanced by extensional tectonics. In steep margins located in the vicinity of major marginal faults, transgressions were characterized by high terrigenous inputs, and only heterozoan-dominated ramps (type 1) developed. The flooding of these steep and tectonically active margins characterized by small drainage basins and immature, locally sourced alluvial systems led to lower terrigenous fluxes and the growth of coral flat-topped platforms (type 2) during subsequent highstands. Away from main marginal faults, deltaic environments were sourced by large drainage basins. They were characterized by a flat topography that permitted the occurrence of a shallow photic zone subject to low and irregular terrigenous inputs up to the distal part of the depositional profile during transgressions. In this deltaic configuration, the growth of narrow siliciclastic-rich coral platforms (type 3) were favored. On these platforms, coral buildups were regularly buried by terrigenous inputs during highstands. In the Lorca Basin, the dimensions of siliciclastic systems and the size of their drainage basins also directly impacted the sequence stratigraphic framework of carbonates intercalated in terrigenous units. This study illustrates the marked variability in: 1) the different types of carbonate depositional profiles and 2) the timing of these carbonates in a mixed carbonate–siliciclastic system because of the size, maturity, and location of siliciclastic systems, local tectonics, inherited topography, and global sea-level fluctuations.
Predicting Photoelectric Logs in Challenging Conditions Using Machine Learning and Statistical Analysis
Authors: Abdullah Eassa , AlYami Reem
Published: November 2024

The photoelectric (PEF) log measures the photoelectric absorption factor, pivotal for determining rock matrix properties. High absorption factor values are typical in limestones, dolomites, clay, iron-bearing minerals, and heavy minerals, whereas sandstones exhibit lower values. In this study, actual photoelectric logs were gathered from the field alongside various other logs such as gallons per minute (GPM), standpipe pressure (SPP), rate of penetration (ROP), and bulk density (RHOB). Utilizing a suite of machine learning regression techniques—ridge regression, linear regression, support vector machines (SVM), polynomial regression, random forest, and decision tree—this research aimed to predict the photoelectric logs using porosity and other log data as inputs. The effectiveness of these models was confirmed through their strong predictive accuracy relative to actual log values. The ensemble of regression models demonstrated significant correlation coefficients and low root mean square errors, illustrating their robust capability to predict photoelectric data at various depths based on available drilling data.
Photonics-based Fully-Connected Hybrid Beamforming: Towards Scaling Up Massive MIMO at Higher Frequency Bands
Authors: Nichols Mitchell , Morison Hugh , Eshaghi Armaghan , Shastri Bhavin , Lampe Lutz
Published: November 2024

Wireless communication at higher frequency bands has attracted significant research interest for fifth generation and beoynd (5GB) wireless networks due to the large amount of unused bandwidth at these frequencies. However, there are substantial challenges associated with higher frequency bands due to the high path loss of the propagation environment and the high power consumption of the transceivers. Hybrid beamforming with massive multiple-input multiple-output (MIMO) has emerged as a solution to these problems by combining the performance and flexibility of digital beamforming with the energy efficiency of analog beamforming. Optical beamforming has recently been considered as an alternative to implement the analog component of a hybrid beamformer, which may offer improvements in size, weight and power consumption in comparison to conventional electronics. This paper proposes a new approach to implement an optical beamforming system based on photonic vector modulators using tunable photonic filters. Our experimental demonstration of the proposed optical beamformer shows that microring resonator (MRR)-based photonic vector modulators can be calibrated to achieve a root-mean-square (RMS) phase error of better than 2◦ and an amplitude error of 0.3 dB. Our findings identify a pathway to realize large scale, fully-connected hybrid beamformers by leveraging the compact and low loss photonics-based weight banks. The photonics-based beamformer can play a pivotal role in scaling up the number of antennas utilized to realize massive and extreme MIMO in 5GB. This is deemed essential specifically at higher frequency bands where conventional electronics fails.
Perioperative outcomes comparisons of thymoma treatment between robot-assisted thymectomy (RAT) and video-assisted thymectomy (VAT)：a meta-analysis
Authors: yu zipu , Jin Xiaoqiang , Zhang Yiran
Published: November 2024

AIM: To conduct a meta-analysis to determine the relative merits between robot-assisted thymectomy (RAT) and video-assisted thymectomy (VAT) in thymoma treatment.
METHODS:
A total of 1860 patients who underwent thymectomy were included in this study. A total of 897 patients underwent RAT, 963 patients underwent VAT. Perioperative outcomes were compared. Pooled odds ratio (OR) and standardized mean differences (SMDs) with 95% confidence intervals (95% CIs) were calculated using either the fixed effects model or the random effects model.
RESULTS: 15 studies were included with a total of 1860 patients, including 897 patients in the RAT group and 963 patients in the VAT group. Compared the perioperative outcomes with VAT, reports of RAT indicated favorable outcomes considering the hospital stay (SMD = -1.81, 95% CI -2.09 to -1.53), estimated blood loss (SMD = -12.55, 95% CI -16.68 to -8.42), duration of chest tube insertion (SMD = -0.47, 95% CI -0.63 to -0.31), volume of drainage (SMD = -79.79, 95% CI -90.72 to -68.86), conversion to open (OR= 0.32, 95% CI 0.18 to 0.58). Meanwhile, the sub-group meta-analysis for hospital stay indicated that RAT yielded a signiﬁcantly shorter time compared with VAT in non-Asian patients (OR= -19.56, 95% CI -29.73 to -9.39). Operative time and ICU stay with RAT were not signiﬁcantly different from VAT (SMD = 1.09; 95% CI -2.35 to 4.53; P = 0.53), (SMD = -0.13; 95% CI -0.32 to 0.06; P = 0.17). The mortality and complications （group and sub-group analysis） rates in both groups were comparable (OR 0.64, 95% CI 0.17–0.24; P = 0.52), (OR 0.92, 95% CI 0.48–1.77; P = 0.80).
CONCLUSION:
Our study suggests that the RATapproach is a feasible alternative approach and even a better option for thymoma surgery treatment. Further studies are required to confirm these results.
GNG2 inhibits brain metastases from colorectal cancer via cell cycle arrest and PI3K/Akt signaling pathway
Authors: Luo Chenhua , Xiao ZhiMing , Yang WenLong
Published: November 2024

G- protein gamma subunit 2 (GNG2) plays a vital role in various cellular processes, but its specific function in colorectal cancer (CRC), particularly in highly invasive cases and brain metastasis, remains unclear. In this study, GNG2 was identified as a key regulator in metastatic colorectal cancer (mCRC) through bioinformatics analysis and experimental validation. Functional enrichment analyses revealed that GNG2 is related to the PI3K/Akt signaling and cell cycle regulation. These findings were further validated by in vitro and in vivo experiments. GNG2 overexpression greatly suppressed proliferation and migration, inhibited the PI3K/Akt axis, and induced G0/G1 arrest in CRC cell lines. In vivo studies, orthotopic xenograft model demonstrated that GNG2 overexpression reduced brain metastasis and extended overall survival in mice. Immunohistochemistry and multiplex immunofluorescence confirmed the association between GNG2 overexpression, the PI3K/Akt signaling pathway, and G0/G1 arrest. Our study suggests that GNG2 contributes to tumor suppression in CRC, particularly in preventing brain metastasis, and could represent a promising biomarker and treatment target for mCRC, contributing fresh insights into the molecular processes driving cancer progression and metastasis.
Efficacy and safety of on-demand tegoprazan therapy in gastroesophageal reflux disease: A multicentre, double-blind, randomised, active-controlled pilot study
Authors: Kang Sun Hyung , Moon Hee Seok , Sung Jae Kyu , Kim Sun Moon , Kim Ki Bae , Lee Seung Woo , Cho Young Sin , Bang Ki Bae , Song Kyung Ho
Published: November 2024

Background
In patients with gastroesophageal reflux disease (GERD) whose symptoms improve with acid-suppression therapy, on-demand treatment could constitute maintenance therapy.
Aims
This study investigated the comparative efficacy and safety of on-demand tegoprazan and proton-pump inhibitor (PPI) therapy in GERD.
Methods
From six university hospitals in the Daejeon-Chungcheong region, we enrolled patients with GERD who had experienced symptomatic improvement with acid-suppressive therapy and, using a randomization table, randomly allocated these participants to two groups: to receive either tegoprazan 50 mg + esomeprazole placebo or tegoprazan placebo + esomeprazole 20 mg, respectively. The primary endpoint of this study was the intergroup difference in patient satisfaction with on-demand therapy.
Results
Among the 69 participants who completed 8 weeks of on-demand therapy and rated patient satisfaction on a 5-point Likert scale, the tegoprazan and esomeprazole groups scored an average of 4.31 and 4.15 points, respectively, without any significant intergroup difference. In the tegoprazan group, 26.2% (182/694) of those with episodes experienced symptom improvement within 30 minutes, which is a significantly higher proportion compared to 16.1% (104/646) in the esomeprazole group. Compared to the esomeprazole group, the tegoprazan group had a significantly shorter time to symptom improvement overall and a significantly higher proportion of patients who improved within 30 minutes. No serious treatment-emergent adverse events were reported.
Conclusion
Tegoprazan is effective as on-demand therapy for GERD and offers the expectation of faster symptom improvement than with PPIs. Clinical trial KCT0009296, registered at cris.nih.go.kr.
Environmental Impact of Disposable Face Masks: Degradation, Wear, and Cement Mortar Incorporation
Authors: Estevão Xiluva Maciel , Dias Ana Paula Soares , Flores-Colen Inês , Pereira Manuel Francisco Costa , Mendes Maria Paula
Published: November 2024

Polypropylene (PP) disposable face masks (DFMs) are essential for limiting airborne infectious diseases. This study examines the behavior of DFMs under three scenarios: i) exposure to the natural environment; ii) simulated high-energy aquatic environments through an abrasion test; and iii) incorporation into cement-based mortars. In the natural weathering experiment, after 117 days, the DFMs exhibited photodegradation, resulting in chemical alterations in carbonyl and hydroxyl groups. This degradation led to the breakdown of the polymer and the release of microplastics and nanoplastics. Controlled abrasion tests, conducted in a Denver ball with water, sand, and ceramic balls for 2 hours, confirmed that water is a critical factor for fiber release from DFMs. These tests resulted in the release of 0.26 g of PP fibers from 20 DFMs (weighing 62 g in total) with a diameter of 20 µm. Weathering and abrasion tests indicated rapid release and degradation of microplastics and nanoplastics, underscoring the importance of pursuing actions like reuse. Ecotoxicological tests revealed that leachates from the DFM-incorporated mortars showed no adverse effects on Daphnia magna or Selenastrum capricornutum, unlike the reference mortar, which caused substantial toxicity to Daphnia magna. Incorporating PP fibers from DFMs into cement-based mortars showed promising potential, as indicated by favorable ecotoxicity and chemical leaching test results.
Home-use Agents in the Treatment of Dentin Hypersensitivity: Clinical Efficacy Evaluation with Different Measurement Methods
Authors: AYAN Gizem , MİSİLLİ Tuğba , BULDUR Mehmet
Published: November 2024

Objectives: This study aimed to evaluate the effectiveness of home-use desensitizing agents over an 8-week period by comparing them using different measurement methods.
Methods: A randomized, controlled clinical trial was conducted with 180 individuals aged between 18-70 who clinically diagnosed DH in two or more non-adjacent teeth. Subjects who met the inclusion criteria (n=164) were randomly allocated into five test groups—using Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), Arginine, Novamin, Propolis, and Potassium nitrate—and a control group using standard fluoride toothpaste. Status of DH was assessed at week 4 and week 8 by the same independent examiner. Changes from baseline in Dentine Hypersensitivity Experience Questionnaire-15 (DHEQ-15), Schiff Sensitivity Scale (SSS) and Visual Analog Scale (VAS) were analysed using ANOVA and Kruskall Wallis tests.
Results: All test groups showed statistically significant improvements in DH at weeks 4 and 8 compared to baseline in the DHEQ-15, VAS, and SSS assessments (p<0.005). In the control group, significant improvements were observed only in the VAS and SSS measurements from baseline to weeks 8 (p<0.005). The CPP-ACP group demonstrated the greatest reduction in scores by the end of week 8 compared to baseline, with DHEQ-15 (56.68±17.87), VAS (6.52±1.48), and SSS (2.32±0.56).
Conclusions: Home-use desensitizing agents effectively treat DH, with the CPP-ACP group being the most effective and the Novamin group relatively less effective.
Clinical relevance: Some home-use desensitizing agents may be more effective in the treatment of DH. In particular, CPP-ACP can be recommended for patients with DH.
Trial registration: ClinicalTrials.gov Identifier: NCT06216262.
Diffuse Contribution of Organic Matter in the Mata dos Cocais Forest, Brazil
Authors: Feitosa Josiana do Nascimento Alves , Coelho Christine Farias , Silva Olga Aline Rodrigues da , De Araújo José Carlos
Published: November 2024

The diffuse contribution of organic matter to rivers, originated by natural weathering, impacts water quality and its monitoring and assessment are essential for hydro-environmental public policies. Yet, this information is unavailable for the Mata dos Cocais, an ecotone that links the Amazon, Caatinga and Cerrado biomes in Brazil. The experiments were carried during 12 months in the 3.53-km downstream reach of the 1540-km² Saco River basin. Mata dos Cocais receives large quantities of organic matter (0.261 mgBOD.L− 1km− 2; 1.22 mgBOD.L− 1km− 1). This outcome is similar to those of other tropical forests in Indonesia, Malaysia, and the Brazilian Cerrado.
Peripheral blood monocyte count impairs benefit from radiotherapy in patients with low gross tumor volume of nasopharyngeal carcinoma
Authors: Song Yun-Rui , Yang Li-Na , Li Dan , Lu Ming-Yue , Liu De-Qing , Tu Hong-Lei , sui Jiang-Dong , Xie Yue , Wang Ying
Published: November 2024

Background and purpose: The relationship between peripheral blood monocyte count and primary gross tumor volume with survival prognosis in newly diagnosed nasopharyngeal carcinoma(NPC) patients who received radiotherapy remains unclear. Therefore, We conducted a cohort study to assess the association of peripheral blood monocyte counts and primary gross tumor volume with survival outcomes in newly diagnosed non-metastatic NPC patients who received radiotherapy.
Materials/Methods: We included newly diagnosed non-metastatic NPC patients who underwent radiotherapy in our hospital from January 2013 to December 2015. General clinical characteristics such as age, gender, ECOG score and tumor stage, peripheral blood monocyte count, lymphocyte count, white blood cell count (WBC), neutrophil count, radiotherapy technology, total radiotherapy days, gross tumor volume of nasopharyngeal carcinoma (GTVnx) and gross tumor volume of cervix node(GTVnd) of patients before radiotherapy, and whether chemotherapy was induced were recorded. The primary endpoint was overall survival, the secondary endpoint was progression-free survival. Univariate and multivariate COX regression were used to analyze the relationship among peripheral blood monocyte count, GTVnx, and survival outcome. Based on the independent risk factors for OS, we further divide patients into three different risk groups, and the differences in clinical and therapeutic indicators and survival outcomes between the three groups were analyzed using a one-way analysis of variance.
Results: A total of 448 participants were included in the study, the median follow-up time was 74.3 months. Of these, 97 (21.7%) died. In the univariate and multivariate Cox regression analyses, peripheral blood monocyte count and GTVnx were independently associated with OS. The high monocyte count and GTVnx were associated with the poor OS and PFS. Survival curves significantly differed among patients in different risk groups for OS (p = 0.0008) and PFS (p = 0.0007). Besides, For every increase in monocyte unit count, the OS and PFS risks of patients in the low GTVnx group increased by 2.64 and 2.31 folds, respectively,.
Conclusions: Peripheral blood monocyte count combined with GTVnx is a independent predictor for overall survival and progression free-survival in newly diagnosed non-metastatic NPC patients who received radiotherapy. The benefit of patients with GTVnx< 28.5cm3 could be remarkably attenuated by the high monocyte count.
Predictive Value of Body Temperature in the Development of Intracranial Infections in Postoperative Patients with Acute Intracerebral Hemorrhage
Authors: Bu Wei , Liang JinQuan , Han Xipeng , Hu Yucheng , Zhang Zhaojun , Zhang Cheng , Shao Min
Published: November 2024

Background
Intracranial infections are among the most severe complications following surgery for acute Intracerebral Hemorrhage (ICH). Study aims to explore link between body temp changes and intracranial infections post-ICH surgery.
Methods
This retrospective study based on whether intracranial infections occurred postoperatively, the 209 patients were categorized into two groups. According to the analysis results of temperature variation trends within 7 days post-surgery for the two patient groups, we employed restricted cubic spline (RCS) and receiver operating characteristic (ROC) curve analysis to evaluate the predictive value of the peak body temperature on the third day for intracranial infection.
Results
Compared to the control group, the intracranial infection group exhibited significantly higher peak temperatures from postoperative day 3, and the difference persisted until postoperative day 7. According to the RCS analysis results, on the 3rd day postoperatively, peak body temperature correlated linearly and positively with intracranial infection. Patients in the high-risk group with a peak body temperature of ≥ 38.2 ℃ on the third day exhibited a significantly higher incidence of intracranial infection (P = 0.005), longer duration of mechanical ventilation and ICU stay.
Conclusions
Our findings preliminarily elucidated the correlation between temperature changes and intracranial infection in postoperative patients with ICH, aiding early warning.
Factors Associated with Treatment Response in Chronic Nonbacterial Osteomyelitis at a Single Center: A Retrospective Cohort Study
Authors: Nowicki Katherine D , Rogers Nathan D , Keeter Carson L , Donaldson Nathan J , Soep Jennifer B , Zhao Yongdong
Published: November 2024

Background NSAIDs are commonly used as first line therapy in chronic nonbacterial osteomyelitis (CNO) but are not effective for all patients. The objective of this study was to identify clinical variables associated with NSAID monotherapy response versus requiring second-line medication in a single-center cohort of patients with CNO.Methods The charts of children with CNO who attended a CNO clinic at a quaternary care center between 1/1/05 and 7/31/21 were retrospectively reviewed. Patients were divided into 3 groups: NSAID-short (NSAID monotherapy for 3 to < 7 months), NSAID-long (NSAID monotherapy for ≥ 7 months), or second-line treatment. Patients were also categorized by which bodily regions were affected by CNO. Multiple linear and logistic regression models were constructed to predict total NSAID monotherapy days and the odds of needing second-line treatment, respectively. These models were optimized using variable combinations that minimized multicollinearity and maximized predictive power, as indicated by minimized AIC values.Results One-hundred-sixty-four patients fulfilled inclusion criteria. Thirty-two patients were in the NSAID-short group, 62 in the NSAID-long group, and 70 in the second-line treatment group. Comparing the two NSAID groups showed that patients with unifocal disease at diagnosis required 47% fewer days of NSAIDs than those with multifocal disease. Results from logistic regression indicated that for each additional region affected, the odds of needing second line treatment increased by 1.94 times (p = 0.01) and that patients with symmetric bone lesions were 6.86 times more likely to require second-line treatment (p < 0.001).Conclusions Patients with unifocal CNO involvement at diagnosis were more likely to require shorter NSAID treatment. Patients with more regions affected and those with symmetric bone lesions were more likely to require second-line treatment.