bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S3 from Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas
Authors: Permuth-Wey Jennifer , Chen Dung-Tsa , Fulp William J. , Yoder Sean J. , Zhang Yonghong , Georgeades Christina , Husain Kazim , Centeno Barbara Ann , Magliocco Anthony M. , Coppola Domenico , Malafa Mokenge
Published: April 2023

A 5-miRNA signature discriminates Malignant (N=21) and Benign (N=21) IPMN Cases. A) Percentage of variation explained in the 5 principal components using the 5 miRNA signature. B) Association of the 5-miRNA signature with IPMN malignancy status. Box plots were used to display the distribution of the IPMN-risk malignancy score within each group. Two-sample t-tests were used to determine associations between the continuous PC1 score and IPMN malignancy status. C) ROC curve analysis of the 5-miRNA signature yielded an AUC of 73.2 (95% CI: 57.6-88.9) in differentiating between groups.
Supplementary Figure S1 from Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas
Authors: Permuth-Wey Jennifer , Chen Dung-Tsa , Fulp William J. , Yoder Sean J. , Zhang Yonghong , Georgeades Christina , Husain Kazim , Centeno Barbara Ann , Magliocco Anthony M. , Coppola Domenico , Malafa Mokenge
Published: April 2023

Flowchart for Statistical Analysis. Circulating miRNAs were evaluated in IPMN cases versus healthy controls and malignant versus benign IPMNs using linear models for microarray data (LIMMA), principal component analysis (PCA), and receiver operating characteristic (ROC) curve analyses, followed by pathway enrichment analyses. We also correlated abundance of plasma miRNAs and tissue miRNAs for cases with both sample types.
Supplementary Figure Legend from Effect of Metformin on Breast Ductal Carcinoma In Situ Proliferation in a Randomized Presurgical Trial
Authors: DeCensi Andrea , Puntoni Matteo , Guerrieri-Gonzaga Aliana , Cazzaniga Massimiliano , Serrano Davide , Lazzeroni Matteo , Vingiani Andrea , Gentilini Oreste , Petrera Marilena , Viale Giuseppe , Cuzick Jack , Bonanni Bernardo , Pruneri Giancarlo
Published: April 2023

Supplementary Figure Legend from Effect of Metformin on Breast Ductal Carcinoma In Situ Proliferation in a Randomized Presurgical Trial
Supplemental Table 1 from Omega-3-Acid Ethyl Esters Block the Protumorigenic Effects of Obesity in Mouse Models of Postmenopausal Basal-like and Claudin-Low Breast Cancer
Authors: Ford Nikki A. , Rossi Emily L. , Barnett Kelsey , Yang Peiying , Bowers Laura W. , Hidaka Brandon H. , Kimler Bruce F. , Carlson Susan E. , Shureiqi Imad , deGraffenried Linda A. , Fabian Carol J. , Hursting Stephen D.
Published: April 2023

Supplemental Table 1. Pilot dosing study - 8 weeks ad libitum consumption. Individual values (n=2) are shown.
Supplementary Figure legends from Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer
Authors: Ichimura Norihisa , Shinjo Keiko , An Byonggu , Shimizu Yasuhiro , Yamao Kenji , Ohka Fumiharu , Katsushima Keisuke , Hatanaka Akira , Tojo Masayuki , Yamamoto Eiichiro , Suzuki Hiromu , Ueda Minoru , Kondo Yutaka
Published: April 2023

Supplementary Figure legends for Supplementary Fig.1 and Fig. 2
Supplementary Fig. 2 from Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer
Authors: Ichimura Norihisa , Shinjo Keiko , An Byonggu , Shimizu Yasuhiro , Yamao Kenji , Ohka Fumiharu , Katsushima Keisuke , Hatanaka Akira , Tojo Masayuki , Yamamoto Eiichiro , Suzuki Hiromu , Ueda Minoru , Kondo Yutaka
Published: April 2023

Supplementary Fig. 2. Genetic and epigenetic alterations in CIMP-P CRCs
Supplementary Table 3 from Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention
Authors: Weinberg David S. , Lin Jieru E. , Foster Nathan R. , Della'Zanna Gary , Umar Asad , Seisler Drew , Kraft Walter K. , Kastenberg David M. , Katz Leo C. , Limburg Paul J. , Waldman Scott A.
Published: April 2023

Cyclic GMP responses in cecal biopsies in subjects receiving linaclotide (Active) or placebo.
Supplementary Table 2 from No Decreased Risk of Gastrointestinal Cancers in Users of Metformin in The Netherlands; A Time-Varying Analysis of Metformin Exposure
Authors: de Jong Roy G. , Burden Andrea M. , de Kort Sander , van Herk-Sukel Myrthe P. , Vissers Pauline A. , Janssen Paddy K. , Haak Harm R. , Masclee Ad A. , de Vries Frank , Janssen-Heijnen Maryska L.
Published: April 2023

Supplementary Table 2. Hazard ratios of GI cancer subsites by sex
Supplemental Figure 3 from Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression In Vivo
Authors: Checkley L. Allyson , Rudolph Michael C. , Wellberg Elizabeth A. , Giles Erin D. , Wahdan-Alaswad Reema S. , Houck Julie A. , Edgerton Susan M. , Thor Ann D. , Schedin Pepper , Anderson Steven M. , MacLean Paul S.
Published: April 2023

Representative electropherograms from ProteinSimple Wes{trade mark, serif} Western Blotting System for p-ACC, total ACC, p-AMPK, and Total AMPK.
Supplementary Table S1-S4 from Single-cell RNA Sequencing Reveals How the Aryl Hydrocarbon Receptor Shapes Cellular Differentiation Potency in the Mouse Colon
Authors: Yang Yongjian , Osorio Daniel , Davidson Laurie A. , Han Huajun , Mullens Destiny A. , Jayaraman Arul , Safe Stephen , Ivanov Ivan , Cai James J. , Chapkin Robert S.
Published: April 2023

Supplementary Table S1. Summary of biomarker genes identified and used in this study. Supplementary Table S2. Results of Kolmogorov-Smirnov tests associated with the velocity length of WT and Ahr KO samples. Supplementary Table S3. CellChat-identified significant ligand-receptor pairs in WT crypt cells. Supplementary Table S4. CellChat-identified significant ligand-receptor pairs in Ahr KO crypt cells.
Supplementary Data from Metformin Use and the Risk of Cancer in Patients with Diabetes: A Nationwide Sample Cohort Study
Authors: Oh Tak Kyu , Song In-Ae
Published: April 2023

Table S1. The trend of metformin exposure from 2011 to 2015 among diabetic patients in 2010
Supplemental Tables from Independent and Joint Effects of Testosterone Replacement Therapy and Statins use on the Risk of Prostate Cancer Among White, Black, and Hispanic Men
Authors: Lopez David S. , Polychronopoulou Efstathia , Tsilidis Konstantinos K. , Khera Mohit , Su L. Joseph , Fowke Jay H. , Peek M.K. , Kuo Yong-Fang , Markides Kyriakos , Canfield Steven
Published: April 2023

Supplemental Table 1 Supplemental Table 2
Supplementary Table 1 from Soy Protein Isolate Protects Against Ethanol-Mediated Tumor Progression in Diethylnitrosamine-Treated Male Mice
Authors: Mercer Kelly E. , Pulliam Casey , Hennings Leah , Lai Keith , Cleves Mario , Jones Ellen , Drake Richard R. , Ronis Martin
Published: April 2023

List of RT-RTPCR primers used in the manuscript.
Supplemental Figure 1 from PAM50 and Risk of Recurrence Scores for Interval Breast Cancers
Authors: Puvanesarajah Samantha , Nyante Sarah J. , Kuzmiak Cherie M. , Chen Mengjie , Tse Chiu-Kit , Sun Xuezheng , Allott Emma H. , Kirk Erin L. , Carey Lisa A. , Perou Charles M. , Olshan Andrew F. , Henderson Louise M. , Troester Melissa A.
Published: April 2023

Flowchart of eligibility criteria.
Supplemental table 1 from Cervical Microbiota Associated with Higher Grade Cervical Intraepithelial Neoplasia in Women Infected with High-Risk Human Papillomaviruses
Authors: Piyathilake Chandrika J. , Ollberding Nicholas J. , Kumar Ranjit , Macaluso Maurizio , Alvarez Ronald D. , Morrow Casey D.
Published: April 2023

Supplemental Table 1. Taxa discriminating on CIN 2+ status.
Supplemental figure 1 from Cervical Microbiota Associated with Higher Grade Cervical Intraepithelial Neoplasia in Women Infected with High-Risk Human Papillomaviruses
Authors: Piyathilake Chandrika J. , Ollberding Nicholas J. , Kumar Ranjit , Macaluso Maurizio , Alvarez Ronald D. , Morrow Casey D.
Published: April 2023

Supplemental Figure 1. A) Non-metric dimensional scaling of the Bray-Curtis metric according to CIN status (ADONIS p=0.30; stress=0.09).
Supplementary Table S4 from Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia
Authors: Delker Don A. , Wood Austin C. , Snow Angela K. , Samadder N. Jewel , Samowitz Wade S. , Affolter Kajsa E. , Boucher Kenneth M. , Pappas Lisa M. , Stijleman Inge J. , Kanth Priyanka , Byrne Kathryn R. , Burt Randall W. , Bernard Philip S. , Neklason Deborah W.
Published: April 2023

Relative reads of Inflammation and Immunity Transcriptome panel on Ion Torrent data sequencer compared with the same genes from RNA sequencing on Illumina HiSeq 2500.
Supplementary Methods from Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia
Authors: Delker Don A. , Wood Austin C. , Snow Angela K. , Samadder N. Jewel , Samowitz Wade S. , Affolter Kajsa E. , Boucher Kenneth M. , Pappas Lisa M. , Stijleman Inge J. , Kanth Priyanka , Byrne Kathryn R. , Burt Randall W. , Bernard Philip S. , Neklason Deborah W.
Published: April 2023

Power calculations for experimental design of RNASeq analysis.
Supplemental Figure Legends from Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype
Authors: Mallery Susan R. , Wang Daren , Santiago Brian , Pei Ping , Schwendeman Steven P. , Nieto Kari , Spinney Richard , Tong Meng , Koutras George , Han Brian , Holpuch Andrew , Lang James
Published: April 2023

Figure legends for supplemental figures.
Supplementary Figure S1 from A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index
Authors: Zell Jason A. , McLaren Christine E. , Morgan Timothy R. , Lawson Michael J. , Rezk Sherif , Albers C. Gregory , Chen Wen-Pin , Carmichael Joseph C. , Chung Jinah , Richmond Ellen , Rodriguez L.M. , Szabo Eva , Ford Leslie G. , Pollak Michael N. , Meyskens Frank L.
Published: April 2023

Supplemental Figure 1. Metformin effects on insulin, AMPK, mTOR
Supplemental Tables 1 and 2 from Longer-term Lipid-lowering Drug Use and Risk of Incident and Fatal Prostate Cancer in Black and White Men in the ARIC Study
Authors: Mondul Alison M. , Joshu Corinne E. , Barber John R. , Prizment Anna E. , Bhavsar Nrupen A. , Selvin Elizabeth , Folsom Aaron R. , Platz Elizabeth A.
Published: April 2023

Supplemental Table 1: Association between lipid-lowering medication use and incident prostate cancer by frequency of routine physical examinations, and among participants who had health insurance or had private health insurance and/or Medicare, men in ARIC (1990-2012). Supplemental Table 2: Association between lipid-lowering medication use and fatal prostate cancer stratified by routine physical examination, and among participants who had health insurance or had private health insurance and/or Medicare, men in ARIC (1990-2012)
Supplementary Table Legends from Effect of Antibiotics on Gut and Vaginal Microbiomes Associated with Cervical Cancer Development in Mice
Authors: Karpinets Tatiana V. , Solley Travis N. , Mikkelson Megan D. , Dorta-Estremera Stephanie , Nookala Sita S. , Medrano Andrea Y. Delgado , Petrosino Joseph F. , Mezzari Melissa P. , Zhang Jinghua , Futreal P. Andrew , Sastry K. Jagannadha , Colbert Lauren E. , Klopp Ann
Published: April 2023

Legends of Supplementary Tables
Adjusted* General Linear Model to Compare The Impact of Metformin on PSA, BMI and LDL between Race/Ethnicity Groups from Metformin for Reducing Racial/Ethnic Difference in Prostate Cancer Incidence for Men with Type II Diabetes
Authors: Wang Chen-Pin , Lehman Donna M. , Lam Yui-Wing F. , Kuhn John G. , Mahalingam Devalingam , Weitman Steven , Lorenzo Carlos , Downs John R. , Stuart Elizabeth A. , Hernandez Javier , Thompson Ian M. , Ramirez Amelie G.
Published: April 2023

The adjustments include covariates: age, HbA1c, Charlson comorbidity, finasteride use, and statin use, and propensity scores for metformin use.
Supplementary Figure S2 from Autofluorescence Imaging to Monitor the Progression of Oral Potentially Malignant Disorders
Authors: Cherry Katelin D. , Schwarz Richard A. , Yang Eric C. , Vohra Imran S. , Badaoui Hawraa , Williams Michelle D. , Vigneswaran Nadarajah , Gillenwater Ann M. , Richards-Kortum Rebecca
Published: April 2023

Eligibility criteria for patients included in the analysis.
Supplementary Methods, Tables S1 - S4, Figure S1 from Dietary Nutrient Intake, Ethnicity, and Epigenetic Silencing of Lung Cancer Genes Detected in Sputum in New Mexican Smokers
Authors: Leng Shuguang , Picchi Maria A. , Kang Huining , Wu Guodong , Filipczak Piotr T. , Juri Daniel E. , Zhang Xiequn , Gauderman W. James , Gilliland Frank D. , Belinsky Steven A.
Published: April 2023

Supplementary Table 1. Association between 139 dietary nutrients and ethnicity (n = 1829)*. Supplementary Table 2. The top ten nutrient measurements in correlation with principal component 2 in either positive or negative direction. Supplementary Table 3. Association between dietary folate intake and risk for methylation (n = 1426)*. Supplementary Table 4. Individual nutrients associated with risk for methylation (n = 1426)*. Supplementary Figure S1. Principal component analysis was conducted based on 101 nutrients with no missing values in 1829 cohort members and identified four principal components that explained 59% of the total variance of nutrients with each one explaining >5% of the variance. This figure included the top nine principal components with each one explaining >2% of the variance. PC = principal component.
Supplementary Tables 1 and 2; Supplementary Figure 1 from 2-Phenethyl Isothiocyanate, Glutathione S-transferase M1 and T1 Polymorphisms, and Detoxification of Volatile Organic Carcinogens and Toxicants in Tobacco Smoke
Authors: Yuan Jian-Min , Murphy Sharon E. , Stepanov Irina , Wang Renwei , Carmella Steven G. , Nelson Heather H. , Hatsukami Dorothy , Hecht Stephen S.
Published: April 2023

Supplemental Table S1. Spearman correlation coefficients between baseline urinary mercapturic acid metabolite of benzene, acrolein and crotonaldehyde, prostaglandin E2 metabolite (PGEM), 8-iso-PGF2α, and metabolites of nicotine and NNK in smokers. Supplemental Table S1. Spearman correlation coefficients between baseline urinary mercapturic acid metabolite of benzene, acrolein and crotonaldehyde, prostaglandin E2 metabolite (PGEM), 8-iso-PGF2α, and metabolites of nicotine and NNK in smokers. Supplemental Table S2. Mean level of urinary levels of PEITC-NAC and total ITC during PEITC treatment by glutathione-S-transferase (GST) genotypes.
Supplementary Data 4 from Breast Cancer Chemoprevention: Use and Views of Australian Women and Their Clinicians
Authors: Macdonald Courtney , Saunders Christobel M. , Keogh Louise A. , Hunter Morgan , Mazza Danielle , McLachlan Sue-Anne , Jones Sandra C. , Nesci Stephanie , Friedlander Michael L. , Hopper John L. , Emery Jon D. , Hickey Martha , Milne Roger L. , Phillips Kelly-Anne
Published: April 2023

Strongest clinician barriers to and facilitators of discussing and prescribing risk reducing medication
Supplementary Data 1 from Breast Cancer Chemoprevention: Use and Views of Australian Women and Their Clinicians
Authors: Macdonald Courtney , Saunders Christobel M. , Keogh Louise A. , Hunter Morgan , Mazza Danielle , McLachlan Sue-Anne , Jones Sandra C. , Nesci Stephanie , Friedlander Michael L. , Hopper John L. , Emery Jon D. , Hickey Martha , Milne Roger L. , Phillips Kelly-Anne
Published: April 2023

Survey sent to kConFab women
Supplementary Figure S1 from The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane
Authors: Hahm Eun-Ryeong , Singh Krishna B. , Kim Su-Hyeong , Powolny Anna A. , Singh Shivendra V.
Published: April 2023

LAMP2 gene expression profile in prostate cancer TCGA.
Supplementary Data from Association of Plasma Iron Status with Subsequent Risk of Total and Site-Specific Cancer: A Large Case–Cohort Study within JPHC Study
Authors: Miyamoto Yoshihisa , Nakano Shiori , Ihira Hikaru , Yamaji Taiki , Katagiri Ryoko , Sawada Norie , Inoue Manami , Tsugane Shoichiro , Iwasaki Motoki
Published: April 2023

Supplementary Data from Association of Plasma Iron Status with Subsequent Risk of Total and Site-Specific Cancer: A Large Case–Cohort Study within JPHC Study
Supplementary Figure S1 from Sulforaphane Suppresses the Growth of Triple-negative Breast Cancer Stem-like Cells In vitro and In vivo
Authors: Castro Nadia P. , Rangel Maria C. , Merchant Anand S. , MacKinnon Gabriel , Cuttitta Frank , Salomon David S. , Kim Young S.
Published: April 2023

SFN modulates CR1 promoter luciferase activity in MDA-MB-231-Luc-D3H1 cells.
Table S2 from The Discovery and Validation of Biomarkers for the Diagnosis of Esophageal Squamous Dysplasia and Squamous Cell Carcinoma
Authors: Couch George , Redman James E. , Wernisch Lorenz , Newton Richard , Malhotra Shalini , Dawsey Sanford M. , Lao-Sirieix Pierre , Fitzgerald Rebecca C.
Published: April 2023

Summary of known the functions and roles in cancer of the 20 genes overexpressed in tumour compared to normal tissue from normal patients. The p value indicates the level of significance for the difference in expression between normal from normal patients (NN) and normal from normal tissue from patients with esophageal cancer.
Table S1 from The Discovery and Validation of Biomarkers for the Diagnosis of Esophageal Squamous Dysplasia and Squamous Cell Carcinoma
Authors: Couch George , Redman James E. , Wernisch Lorenz , Newton Richard , Malhotra Shalini , Dawsey Sanford M. , Lao-Sirieix Pierre , Fitzgerald Rebecca C.
Published: April 2023

Antibodies used and the conditions for immunohistochemistry.
Figure S1 from The Discovery and Validation of Biomarkers for the Diagnosis of Esophageal Squamous Dysplasia and Squamous Cell Carcinoma
Authors: Couch George , Redman James E. , Wernisch Lorenz , Newton Richard , Malhotra Shalini , Dawsey Sanford M. , Lao-Sirieix Pierre , Fitzgerald Rebecca C.
Published: April 2023

Representative examples of SVM separation score data selected from the 100 genes with the highest SVM scores using a random number generator. The x-axis shows the sample number; normal samples are on the left of each graph, tumour samples on the right separated by a red bar. The horizontal lines represent the means of the expression scores for the normal and tumour samples respectively.
Table S4 from Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial
Authors: Zarei Iman , Baxter Bridget A. , Oppel Renee C. , Borresen Erica C. , Brown Regina J. , Ryan Elizabeth P.
Published: April 2023

Supplementary Table 4
Table S3 from Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial
Authors: Zarei Iman , Baxter Bridget A. , Oppel Renee C. , Borresen Erica C. , Brown Regina J. , Ryan Elizabeth P.
Published: April 2023

Supplementary Table 3
Supplementary Figures and Supplementary Table 1 from Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial
Authors: Zarei Iman , Baxter Bridget A. , Oppel Renee C. , Borresen Erica C. , Brown Regina J. , Ryan Elizabeth P.
Published: April 2023

Supplementary Figures S1-4 with attached Figure Legends plus Supplementary Table 1 accompanied by Table Legends for Supplementary Tables 2-4
Supplementary Tables 1, 2, 3 and 4 from Knowledge of Potential Harms and Benefits of Tamoxifen among Women Considering Breast Cancer Preventive Therapy
Authors: Thorneloe Rachael Jane , Hall Louise Hazel , Walter Fiona Mary , Side Lucy , Lloyd Kelly Elizabeth , Smith Samuel George
Published: April 2023

Supplementary Tables 1, 2, 3 and 4
Supplementary Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis
Authors: Thomas Chloe , Mandrik Olena , Saunders Catherine L. , Thompson Deborah , Whyte Sophie , Griffin Simon , Usher-Smith Juliet A.
Published: April 2023

Supplementary Data from The Costs and Benefits of Risk Stratification for Colorectal Cancer Screening Based On Phenotypic and Genetic Risk: A Health Economic Analysis
Supplementary Appendix from Knowledge of Potential Harms and Benefits of Tamoxifen among Women Considering Breast Cancer Preventive Therapy
Authors: Thorneloe Rachael Jane , Hall Louise Hazel , Walter Fiona Mary , Side Lucy , Lloyd Kelly Elizabeth , Smith Samuel George
Published: April 2023

Supplementary Appendix reporting exploratory sensitivity analysis
Supplementary Table 5 from Physical Activity and Long-term Quality of Life among Colorectal Cancer Survivors—A Population-based Prospective Study
Authors: Eyl Ruth Elisa , Koch-Gallenkamp Lena , Jansen Lina , Walter Viola , Carr Prudence R. , Hoffmeister Michael , Chang-Claude Jenny , Brenner Hermann , Arndt Volker
Published: April 2023

Supplementary Table 5
Supplementary Table 1 from Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy
Authors: Mullooly Maeve , Puvanesarajah Samantha , Fan Shaoqi , Pfeiffer Ruth M. , Olsson Linnea T. , Hada Manila , Kirk Erin L. , Vacek Pamela M. , Weaver Donald L. , Shepherd John , Mahmoudzadeh Amir , Wang Jeff , Malkov Serghei , Johnson Jason M. , Hewitt Stephen M. , Herschorn Sally D. , Sherman Mark E. , Troester Melissa A. , Gierach Gretchen L.
Published: April 2023

Supplementary Table 1
Document for the supplementary table legends from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia
Authors: Cómbita Alba Lucía , Gheit Tarik , González Paula , Puerto Devi , Murillo Raúl Hernando , Montoya Luisa , Vorsters Alex , Van Keer Severien , Van Damme Pierre , Tommasino Massimo , Hernández-Suárez Gustavo , Sánchez Laura , Herrero Rolando , Wiesner Carolina
Published: April 2023

Document for the supplementary table legends.
Supplementary Figure 1 from Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy
Authors: Mullooly Maeve , Puvanesarajah Samantha , Fan Shaoqi , Pfeiffer Ruth M. , Olsson Linnea T. , Hada Manila , Kirk Erin L. , Vacek Pamela M. , Weaver Donald L. , Shepherd John , Mahmoudzadeh Amir , Wang Jeff , Malkov Serghei , Johnson Jason M. , Hewitt Stephen M. , Herschorn Sally D. , Sherman Mark E. , Troester Melissa A. , Gierach Gretchen L.
Published: April 2023

Supplementary Figure 1
Supplementary Figure S2 from Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
Authors: Young Adelaide , Bu Wen , Jiang Weiyu , Ku Amy , Kapali Jyoti , Dhamne Sagar , Qin Lan , Hilsenbeck Susan G. , Du Yi-Chieh Nancy , Li Yi
Published: April 2023

Supplementary Figure S2 shows detection of BCL-2 family members in PIK3CAH1047R tumors from mice prophylactically treated with venetoclax.
Supplemental Table S7 from Effect of Green Tea Supplements on Liver Enzyme Elevation: Results from a Randomized Intervention Study in the United States
Authors: Yu Zheming , Samavat Hamed , Dostal Allison M. , Wang Renwei , Torkelson Carolyn J. , Yang Chung S. , Butler Lesley M. , Kensler Thomas W. , Wu Anna H. , Kurzer Mindy S. , Yuan Jian-Min
Published: April 2023

Supplemental Table S7 shows ALT, AST, alkaline phosphatase and total bilirubin results and self-reported symptoms for eight women whose ALT increased above 300 U/L over the course of treatment with GTE or placebo.
Supplemental Table S4 from Effect of Green Tea Supplements on Liver Enzyme Elevation: Results from a Randomized Intervention Study in the United States
Authors: Yu Zheming , Samavat Hamed , Dostal Allison M. , Wang Renwei , Torkelson Carolyn J. , Yang Chung S. , Butler Lesley M. , Kensler Thomas W. , Wu Anna H. , Kurzer Mindy S. , Yuan Jian-Min
Published: April 2023

Supplemental Table S4 shows the grading of ALT during the 12-month treatment period by the level of baseline liver function tests and the interaction with treatment assignment (GTE or Placebo).
Supplementary Figure S1 from Effects of Walnut Consumption on Colon Carcinogenesis and Microbial Community Structure
Authors: Nakanishi Masako , Chen Yanfei , Qendro Veneta , Miyamoto Shingo , Weinstock Erica , Weinstock George M. , Rosenberg Daniel W.
Published: April 2023

Number of ACF and colon tumors by gender in Study 1.
Supplementary Tables S1-S2 from Three-Year Interval for the Multi-Target Stool DNA Test for Colorectal Cancer Screening: A Longitudinal Study
Authors: Imperiale Thomas F. , Lavin Philip T. , Marti Tara N. , Jakubowski Debbie , Itzkowitz Steven H. , May Folasade P. , Limburg Paul J. , Sweetser Seth , Daghestani Anas , Berger Barry M.
Published: April 2023

Supplemental Table S1: Distribution of colorectal lesions among subjects at baseline (T0) and year 3 (T3). Supplemental Table S2: Study subject accountability in the baseline negative population
Data from Metabolomic, DNA Methylomic, and Transcriptomic Profiling of Suberoylanilide Hydroxamic Acid Effects on LPS-Exposed Lung Epithelial Cells
Authors: Chou Pochung Jordan , Sarwar Md Shahid , Wang Lujing , Wu Renyi , Li Shanyi , Hudlikar Rasika R. , Wang Yujue , Su Xiaoyang , Kong Ah-Ng
Published: April 2023

Abstract
Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase (HDAC) inhibitor with anticancer effects via epigenetic and non-epigenetic mechanisms. The role of SAHA in metabolic rewiring and epigenomic reprogramming to inhibit pro-tumorigenic cascades in lung cancer remains unknown. In this study, we aimed to investigate the regulation of mitochondrial metabolism, DNA methylome reprogramming, and transcriptomic gene expression by SAHA in lipopolysaccharide (LPS)-induced inflammatory model of lung epithelial BEAS-2B cells. LC/MS was used for metabolomic analysis, while next-generation sequencing was done to study epigenetic changes. The metabolomic study reveals that SAHA treatment significantly regulated methionine, glutathione, and nicotinamide metabolism with alteration of the metabolite levels of methionine, S-adenosylmethionine, S-adenosylhomocysteine, glutathione, nicotinamide, 1-methylnicotinamide, and nicotinamide adenine dinucleotide in BEAS-2B cells. Epigenomic CpG methyl-seq shows SAHA revoked a list of differentially methylated regions in the promoter region of the genes, such as HDAC11, miR4509–1, and miR3191. Transcriptomic RNA sequencing (RNA-seq) reveals SAHA abrogated LPS-induced differentially expressed genes encoding proinflammatory cytokines, including interleukin 1α (IL1α), IL1β, IL2, IL6, IL24, and IL32. Integrative analysis of DNA methylome-RNA transcriptome displays a list of genes, of which CpG methylation correlated with changes in gene expression. qPCR validation of transcriptomic RNA-seq data shows that SAHA treatment significantly reduced the LPS-induced mRNA levels of IL1β, IL6, DNA methyltransferase 1 (DNMT1), and DNMT3A in BEAS-2B cells. Altogether, SAHA treatment alters the mitochondrial metabolism, epigenetic CpG methylation, and transcriptomic gene expression to inhibit LPS-induced inflammatory responses in lung epithelial cells, which may provide novel molecular targets to inhibit the inflammation component of lung carcinogenesis.
Prevention Relevance:
Inflammation increases the risk of lung cancer and blocking inflammation could reduce the incidence of lung cancer. Herein, we demonstrate that histone deacetylase inhibitor suberoylanilide hydroxamic acid regulates metabolic rewiring and epigenetic reprogramming to attenuate lipopolysaccharide-driven inflammation in lung epithelial cells.
Supplementary Figure 5 from Chimeric Transcript Generated by cis-Splicing of Adjacent Genes Regulates Prostate Cancer Cell Proliferation
Authors: Zhang Yanmei , Gong Mei , Yuan Huiling , Park Hong G. , Frierson Henry F. , Li Hui
Published: April 2023

PDF file - 384K, Structure of wild type SLC45A3 and ELK4 genes and SLC45A3-ELK4 chimeric transcript
Supplementary Figure S11 from Bone Marrow–Derived Gr1+ Cells Can Generate a Metastasis-Resistant Microenvironment Via Induced Secretion of Thrombospondin-1
Authors: Catena Raúl , Bhattacharya Nandita , El Rayes Tina , Wang Suming , Choi Hyejin , Gao Dingcheng , Ryu Seongho , Joshi Natasha , Bielenberg Diane , Lee Sharrell B. , Haukaas Svein A. , Gravdal Karsten , Halvorsen Ole J. , Akslen Lars A. , Watnick Randolph S. , Mittal Vivek
Published: April 2023

Supplementary Figure S11 - PDF file 256K, Saposin A stimulates Tsp-1 expression in vitro
Supplementary Table S1 from Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1
Authors: Laine Anni , Sihto Harri , Come Christophe , Rosenfeldt Mathias T. , Zwolinska Aleksandra , Niemelä Minna , Khanna Anchit , Chan Edward K. , Kähäri Veli-Matti , Kellokumpu-Lehtinen Pirkko-Liisa , Sansom Owen J. , Evan Gerard I. , Junttila Melissa R. , Ryan Kevin M. , Marine Jean-Christophe , Joensuu Heikki , Westermarck Jukka
Published: April 2023

Supplementary Table S1 PDF file - 71K, CIP2A overexpression frequencies and clinical relevance in human cancer types
Supplementary Figure 3 from Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1
Authors: Laine Anni , Sihto Harri , Come Christophe , Rosenfeldt Mathias T. , Zwolinska Aleksandra , Niemelä Minna , Khanna Anchit , Chan Edward K. , Kähäri Veli-Matti , Kellokumpu-Lehtinen Pirkko-Liisa , Sansom Owen J. , Evan Gerard I. , Junttila Melissa R. , Ryan Kevin M. , Marine Jean-Christophe , Joensuu Heikki , Westermarck Jukka
Published: April 2023

Supplementary Figure 3 PDF file - 114K, RB expression is not needed for CIP2A-depletion induced senescence
Supplementary Video 3 from Reversing Resistance to Vascular-Disrupting Agents by Blocking Late Mobilization of Circulating Endothelial Progenitor Cells
Authors: Taylor Melissa , Billiot Fanny , Marty Virginie , Rouffiac Valérie , Cohen Patrick , Tournay Elodie , Opolon Paule , Louache Fawzia , Vassal Gilles , Laplace-Builhé Corinne , Vielh Philippe , Soria Jean-Charles , Farace Françoise
Published: April 2023

AVI file - 2MB
Supplementary Figure 1 from Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1
Authors: Laine Anni , Sihto Harri , Come Christophe , Rosenfeldt Mathias T. , Zwolinska Aleksandra , Niemelä Minna , Khanna Anchit , Chan Edward K. , Kähäri Veli-Matti , Kellokumpu-Lehtinen Pirkko-Liisa , Sansom Owen J. , Evan Gerard I. , Junttila Melissa R. , Ryan Kevin M. , Marine Jean-Christophe , Joensuu Heikki , Westermarck Jukka
Published: April 2023

Supplementary Figure 1 PDF file - 48K, CIP2A expression and correlation with clinicopathological markers of advanced disease in unselected human breast cancer material
Supplementary Video 1 from Reversing Resistance to Vascular-Disrupting Agents by Blocking Late Mobilization of Circulating Endothelial Progenitor Cells
Authors: Taylor Melissa , Billiot Fanny , Marty Virginie , Rouffiac Valérie , Cohen Patrick , Tournay Elodie , Opolon Paule , Louache Fawzia , Vassal Gilles , Laplace-Builhé Corinne , Vielh Philippe , Soria Jean-Charles , Farace Françoise
Published: April 2023

AVI file - 1.5MB
Supplementary Table 1, Figures 1-8, Movie Legends 1-4 from Reversing Resistance to Vascular-Disrupting Agents by Blocking Late Mobilization of Circulating Endothelial Progenitor Cells
Authors: Taylor Melissa , Billiot Fanny , Marty Virginie , Rouffiac Valérie , Cohen Patrick , Tournay Elodie , Opolon Paule , Louache Fawzia , Vassal Gilles , Laplace-Builhé Corinne , Vielh Philippe , Soria Jean-Charles , Farace Françoise
Published: April 2023

PDF file - 1MB
Supplementary Table 6 from Integrative Epigenomic Analysis Identifies Biomarkers and Therapeutic Targets in Adult B-Acute Lymphoblastic Leukemia
Authors: Geng Huimin , Brennan Sarah , Milne Thomas A. , Chen Wei-Yi , Li Yushan , Hurtz Christian , Kweon Soo-Mi , Zickl Lynette , Shojaee Seyedmehdi , Neuberg Donna , Huang Chuanxin , Biswas Debabrata , Xin Yuan , Racevskis Janis , Ketterling Rhett P. , Luger Selina M. , Lazarus Hillard , Tallman Martin S. , Rowe Jacob M. , Litzow Mark R. , Guzman Monica L. , Allis C. David , Roeder Robert G. , Müschen Markus , Paietta Elisabeth , Elemento Olivier , Melnick Ari M.
Published: April 2023

XLS file - 45K, Detailed genes in the lymphoid gene sets and gene ontology terms
Supplementary Figure 4 from Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis
Authors: Eisinger-Mathason T.S. Karin , Zhang Minsi , Qiu Qiong , Skuli Nicolas , Nakazawa Michael S. , Karakasheva Tatiana , Mucaj Vera , Shay Jessica E.S. , Stangenberg Lars , Sadri Navid , Puré Ellen , Yoon Sam S. , Kirsch David G. , Simon M. Celeste
Published: April 2023

Supplementary Figure 4 - PDF file 151K,HIF1{alpha} and PLOD2 mediate migration via a cell extrinsic mechanism in KP cells
Supplementary Figure 3 from Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis
Authors: Eisinger-Mathason T.S. Karin , Zhang Minsi , Qiu Qiong , Skuli Nicolas , Nakazawa Michael S. , Karakasheva Tatiana , Mucaj Vera , Shay Jessica E.S. , Stangenberg Lars , Sadri Navid , Puré Ellen , Yoon Sam S. , Kirsch David G. , Simon M. Celeste
Published: April 2023

Supplementary Figure 3 - PDF file 97K, HIF1{alpha} and PLOD2 mediate sarcoma cell migration
Supplementary Figure 2 from Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis
Authors: Eisinger-Mathason T.S. Karin , Zhang Minsi , Qiu Qiong , Skuli Nicolas , Nakazawa Michael S. , Karakasheva Tatiana , Mucaj Vera , Shay Jessica E.S. , Stangenberg Lars , Sadri Navid , Puré Ellen , Yoon Sam S. , Kirsch David G. , Simon M. Celeste
Published: April 2023

Supplementary Figure 2 - PDF file 124K, HIF1{alpha} is not required for primary sarcoma formation
Supplementary Figure 1 from Forced Mitotic Entry of S-Phase Cells as a Therapeutic Strategy Induced by Inhibition of WEE1
Authors: Aarts Marieke , Sharpe Rachel , Garcia-Murillas Isaac , Gevensleben Heidrun , Hurd Melissa S. , Shumway Stuart D. , Toniatti Carlo , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF file - 95K, Inhibition or silencing of WEE1 triggers premature mitosis
Figure S8 from Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
Authors: Strohecker Anne M. , Guo Jessie Yanxiang , Karsli-Uzunbas Gizem , Price Sandy M. , Chen Guanghua Jim , Mathew Robin , McMahon Martin , White Eileen
Published: April 2023

Figure S8 - PDF file 704K, Tp53-/-;Braf V600E/+; Atg7-/- derived TDCLs fail to accumulate neutral lipids during starvation
Figure S7 from Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of BrafV600E–Driven Lung Tumors
Authors: Strohecker Anne M. , Guo Jessie Yanxiang , Karsli-Uzunbas Gizem , Price Sandy M. , Chen Guanghua Jim , Mathew Robin , McMahon Martin , White Eileen
Published: April 2023

Figure S7 - PDF file 564K, ROS scavenging is not sufficient to rescue death of the ATG7-deficient TDCLs during starvation
Supplementary Figures 1-13 from microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma
Authors: Genovese Giannicola , Ergun Ayla , Shukla Sachet A. , Campos Benito , Hanna Jason , Ghosh Papia , Quayle Steven N. , Rai Kunal , Colla Simona , Ying Haoqiang , Wu Chang-Jiun , Sarkar Sharmistha , Xiao Yonghong , Zhang Jianhua , Zhang Hailei , Kwong Lawrence , Dunn Katherine , Wiedemeyer Wolf Ruprecht , Brennan Cameron , Zheng Hongwu , Rimm David L. , Collins James J. , Chin Lynda
Published: April 2023

PDF file - 854K, Supplementary Figure 1: miR-mRNA relationship (miR-34a; PDGFRA) detected by CLR in all GBM samples. Supplementary Figure 2: loss of p53 and Pten in murine neural stem cells and progenitor cells promotes the formation of proneural malignant gliomas. Supplementary Figure 3: expression levels of the subtype-specific miRNAs in p53/Pten-/- E13 embryonic neural stem cells infected with lentiviral miRNA precursors. Supplementary Figure 4: miR-34a expression in an independent cohort of GBM by in situ hybridization. Supplementary Figure 5: miR-34a levels in human and mouse proneural GBM. Supplementary Figure 6: miR-34a impairs tumor formation in orthotopic transplants. Supplementary Figure 7: miR-34a impairs the self-renewal of human proneural malignant spheroids. Supplementary Figure 8: miR-34a loss induces the expression of its oncogenic targets. Supplementary Figure 9: validation of PDGFRA as a direct target of miR-34a. Supplementary Figure 10: PDGFRA rescue on the self-renewal phenotype caused by miR-34a over-expression. Supplementary Figure 11: inverse correlation between the expression levels of miR-34a, PDGFRA and Smad4 in the GBM TCGA dataset. Supplementary Figure 12: validation of Smad4 as a direct target of miR-34a. Supplementary Figure 13: Smad4 rescue on the self-renewal phenotype caused by miR-34a over-expression
Supplementary Tables 1-2, Figures 1-8 from PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
Authors: Ying Haoqiang , Elpek Kutlu G. , Vinjamoori Anant , Zimmerman Stephanie M. , Chu Gerald C. , Yan Haiyan , Fletcher-Sananikone Eliot , Zhang Hailei , Liu Yingchun , Wang Wei , Ren Xiaojia , Zheng Hongwu , Kimmelman Alec C. , Paik Ji-hye , Lim Carol , Perry Samuel R. , Jiang Shan , Malinn Brian , Protopopov Alexei , Colla Simona , Xiao Yonghong , Hezel Aram F. , Bardeesy Nabeel , Turley Shannon J. , Wang Y. Alan , Chin Lynda , Thayer Sarah P. , DePinho Ronald A.
Published: April 2023

Supplementary Tables 1-2, Figures 1-8 from PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-κB–Cytokine Network
Supplementary Figures Legends 1-8, Table Legends 1-9, Methods from CD36 Repression Activates a Multicellular Stromal Program Shared by High Mammographic Density and Tumor Tissues
Authors: DeFilippis Rosa Anna , Chang Hang , Dumont Nancy , Rabban Joseph T. , Chen Yunn-Yi , Fontenay Gerald V. , Berman Hal K. , Gauthier Mona L. , Zhao Jianxin , Hu Donglei , Marx James J. , Tjoe Judy A. , Ziv Elad , Febbraio Maria , Kerlikowske Karla , Parvin Bahram , Tlsty Thea D.
Published: April 2023

PDF file - 131K
Supplementary Figure S1 from Relief of Feedback Inhibition of HER3 Transcription by RAF and MEK Inhibitors Attenuates Their Antitumor Effects in BRAF-Mutant Thyroid Carcinomas
Authors: Montero-Conde Cristina , Ruiz-Llorente Sergio , Dominguez Jose M. , Knauf Jeffrey A. , Viale Agnes , Sherman Eric J. , Ryder Mabel , Ghossein Ronald A. , Rosen Neal , Fagin James A.
Published: April 2023

Supplementary Figure S1 PDF file - 51K, A, Lineage-specific differences in effects of PLX4032 on RAS/RAF/MAPK signaling. DUSP5 expression kinetics in a panel of BRAF wild type (Top) and BRAF mutant (Bottom) cell lines treated with 2 �gM PLX4032 for 1, 6 or 48 h. Points represent DUSP5/GAPDH Q-RT-PCR values of triplicate assays (mean +/- SD). B, Re-addition of AZD6244 blocks PLX4032 induction of ERK1/2 phosphorylation. 8505C cells were treated with PLX4032 for the indicated times and then re-treated with either fresh PLX4032 or MEK inhibitor AZD6244 for an additional 1, 6 or 24 h. Proteins were extracted and immunobloted for pERK and tERK
Supplementary Figures 1-6, Tables 1-2, Methods from Genetic and Functional Studies Implicate HIF1α as a 14q Kidney Cancer Suppressor Gene
Authors: Shen Chuan , Beroukhim Rameen , Schumacher Steven E. , Zhou Jing , Chang Michelle , Signoretti Sabina , Kaelin William G.
Published: April 2023

Supplementary Figures 1-6, Tables 1-2, Methods from Genetic and Functional Studies Implicate HIF1α as a 14q Kidney Cancer Suppressor Gene
Supplementary Figures 1-12 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment
Authors: Nishimura Masato , Jung Eun-Jung , Shah Maitri Y. , Lu Chunhua , Spizzo Riccardo , Shimizu Masayoshi , Han Hee Dong , Ivan Cristina , Rossi Simona , Zhang Xinna , Nicoloso Milena S. , Wu Sherry Y. , Almeida Maria Ines , Bottsford-Miller Justin , Pecot Chad V. , Zand Behrouz , Matsuo Koji , Shahzad Mian M. , Jennings Nicholas B. , Rodriguez-Aguayo Cristian , Lopez-Berestein Gabriel , Sood Anil K. , Calin George A.
Published: April 2023

Supplementary Figures 1-12 - PDF file 897K, Relative expression of miR-520d-3p (miR-520d) and miR-520d-5p (miR-520d*) in ovarian cancer cell lines (Figure S1), Kaplan-Meier curves representing the percent progression-free survival in patients with ovarian cancer based on miR-520d-3p median expression levels (Figure S2), miR-520d-5p does not target EphA2 (Figure S3), miR-520d-3p and EphA2 expression levels in miR-520d-3p overexpressing stable clones (Figure S4), Effect of miR-520d-3p expression on cell proliferation (Figure S5), miR-520d-3p and EphA2 levels in xenograft models of miR-520d-3p overexpressing HeyA8 and SKOV3ip1 models (Figure S6), Efficiency of EphA2 targeting siRNAs in HeyA8 cells (Figure S7), Combination of miR-520d-3p and siRNA-EphA2 treatment shows enhanced EphA2 inhibition in vitro (Figure S8), Dose-response curve of miR-520d-3p, si-EphA2-1 and combined miR-520d-3p + si-EphA2-1 in SKOV3ip1 and HeyA8 cells (Figure S9), Treatment with anti-miR-520d-3p can restore EphA2 protein levels in a dose-dependent manner in SKOV3ip1 cells (Figure S10), Effect of combined miR-520d-3p+siEphA2-1 treatment on angiogenesis, proliferation and apoptosis in HeyA8 cells (Figure S11), and Differentially expressed coding genes in miR-520d-3p overexpressing stable clones (Figure S12)
Supplementary Figure 2 from Antagonism of Inhibitor of Apoptosis Proteins Increases Bone Metastasis via Unexpected Osteoclast Activation
Authors: Yang Chang , Davis Jennifer L. , Zeng Rong , Vora Paras , Su Xinming , Collins Lynne I. , Vangveravong Suwanna , Mach Robert H. , Piwnica-Worms David , Weilbaecher Katherine N. , Faccio Roberta , Veis Novack Deborah
Published: April 2023

PDF file - 248K,DNA fragmentation and BrdU incorporation assays on mouse and human osteoclast precursors, in response to BV6
Supplementary Figure 1 from Antagonism of Inhibitor of Apoptosis Proteins Increases Bone Metastasis via Unexpected Osteoclast Activation
Authors: Yang Chang , Davis Jennifer L. , Zeng Rong , Vora Paras , Su Xinming , Collins Lynne I. , Vangveravong Suwanna , Mach Robert H. , Piwnica-Worms David , Weilbaecher Katherine N. , Faccio Roberta , Veis Novack Deborah
Published: April 2023

PDF file - 593K, MicroCT analysis of bone in BV6-treated C57BL/6 mice
Supplementary Figures 1-11, Methods from A20 Ubiquitin Ligase–Mediated Polyubiquitination of RIP1 Inhibits Caspase-8 Cleavage and TRAIL-Induced Apoptosis in Glioblastoma
Authors: Bellail Anita C. , Olson Jeffrey J. , Yang Xiaolu , Chen Zhijian J. , Hao Chunhai
Published: April 2023

PDF file - 1.4MB
Supplementary Figure 4 from Temporal Dissection of Tumorigenesis in Primary Cancers
Authors: Durinck Steffen , Ho Christine , Wang Nicholas J. , Liao Wilson , Jakkula Lakshmi R. , Collisson Eric A. , Pons Jennifer , Chan Sai-Wing , Lam Ernest T. , Chu Catherine , Park Kyunghee , Hong Sung-woo , Hur Joe S. , Huh Nam , Neuhaus Isaac M. , Yu Siegrid S. , Grekin Roy C. , Mauro Theodora M. , Cleaver James E. , Kwok Pui-Yan , LeBoit Philip E. , Getz Gad , Cibulskis Kristian , Aster Jon C. , Huang Haiyan , Purdom Elizabeth , Li Jian , Bolund Lars , Arron Sarah T. , Gray Joe W. , Spellman Paul T. , Cho Raymond J.
Published: April 2023

Supplementary Figure 4 from Temporal Dissection of Tumorigenesis in Primary Cancers
Supplementary Figure 1 from Temporal Dissection of Tumorigenesis in Primary Cancers
Authors: Durinck Steffen , Ho Christine , Wang Nicholas J. , Liao Wilson , Jakkula Lakshmi R. , Collisson Eric A. , Pons Jennifer , Chan Sai-Wing , Lam Ernest T. , Chu Catherine , Park Kyunghee , Hong Sung-woo , Hur Joe S. , Huh Nam , Neuhaus Isaac M. , Yu Siegrid S. , Grekin Roy C. , Mauro Theodora M. , Cleaver James E. , Kwok Pui-Yan , LeBoit Philip E. , Getz Gad , Cibulskis Kristian , Aster Jon C. , Huang Haiyan , Purdom Elizabeth , Li Jian , Bolund Lars , Arron Sarah T. , Gray Joe W. , Spellman Paul T. , Cho Raymond J.
Published: April 2023

Supplementary Figure 1 from Temporal Dissection of Tumorigenesis in Primary Cancers
Supplementary Table 1 from Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
Authors: Yang Annan , Rajeshkumar N.V. , Wang Xiaoxu , Yabuuchi Shinichi , Alexander Brian M. , Chu Gerald C. , Von Hoff Daniel D. , Maitra Anirban , Kimmelman Alec C.
Published: April 2023

PDF file - 18KB, Summary of genetic mutations in different human pancreatic tumor xenografts.
Supplementary Figure 5 from Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
Authors: Yang Annan , Rajeshkumar N.V. , Wang Xiaoxu , Yabuuchi Shinichi , Alexander Brian M. , Chu Gerald C. , Von Hoff Daniel D. , Maitra Anirban , Kimmelman Alec C.
Published: April 2023

PDF file - 162KB, PCR and western blot confirmed the genotype of mouse cell lines with different p53 status.
Supplementary Figure Legends from An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101
Authors: Doebele Robert C. , Davis Lara E. , Vaishnavi Aria , Le Anh T. , Estrada-Bernal Adriana , Keysar Stephen , Jimeno Antonio , Varella-Garcia Marileila , Aisner Dara L. , Li Yali , Stephens Philip J. , Morosini Deborah , Tuch Brian B. , Fernandes Michele , Nanda Nisha , Low Jennifer A.
Published: April 2023

Supplementary Figure Legends
Supplementary Material from Selective Estrogen Receptor Modulators and Pharmacogenomic Variation in ZNF423 Regulation of BRCA1 Expression: Individualized Breast Cancer Prevention
Authors: Ingle James N. , Liu Mohan , Wickerham D. Lawrence , Schaid Daniel J. , Wang Liewei , Mushiroda Taisei , Kubo Michiaki , Costantino Joseph P. , Vogel Victor G. , Paik Soonmyung , Goetz Matthew P. , Ames Matthew M. , Jenkins Gregory D. , Batzler Anthony , Carlson Erin E. , Flockhart David A. , Wolmark Norman , Nakamura Yusuke , Weinshilboum Richard M.
Published: April 2023

Supplementary Material - PDF file 131K, Provision of Supplementary material relating to methods, tables for patient characteristics, SNP-covariate interactions, SNP effects on time to breast cancer, top SNPs on chromosomes 4 and 16, and supplementary Figure legends
Supplementary Figure S4 from Selective Estrogen Receptor Modulators and Pharmacogenomic Variation in ZNF423 Regulation of BRCA1 Expression: Individualized Breast Cancer Prevention
Authors: Ingle James N. , Liu Mohan , Wickerham D. Lawrence , Schaid Daniel J. , Wang Liewei , Mushiroda Taisei , Kubo Michiaki , Costantino Joseph P. , Vogel Victor G. , Paik Soonmyung , Goetz Matthew P. , Ames Matthew M. , Jenkins Gregory D. , Batzler Anthony , Carlson Erin E. , Flockhart David A. , Wolmark Norman , Nakamura Yusuke , Weinshilboum Richard M.
Published: April 2023

Supplementary Figure S4 - PDF file 23K, CTSO and BRCA1 expression in LCLs with variant and wild type genotypes
Supplementary Figure Legends from Primary Melanoma of the CNS in Children Is Driven by Congenital Expression of Oncogenic NRAS in Melanocytes
Authors: Pedersen Malin , Küsters-Vandevelde Heidi V.N. , Viros Amaya , Groenen Patricia J.T.A. , Sanchez-Laorden Berta , Gilhuis Jacobus H. , van Engen-van Grunsven Ilse A. , Renier Willy , Schieving Jolanda , Niculescu-Duvaz Ion , Springer Caroline J. , Küsters Benno , Wesseling Pieter , Blokx Willeke A.M. , Marais Richard
Published: April 2023

Supplementary Figure Legends PDF file - 92K, This file contains the Figure legends to Supplementary Figures 1-5
Figure S1 from Restricted Expression of miR-30c-2-3p and miR-30a-3p in Clear Cell Renal Cell Carcinomas Enhances HIF2α Activity
Authors: Mathew Lijoy K. , Lee Samuel S. , Skuli Nicolas , Rao Shilpa , Keith Brian , Nathanson Katherine L. , Lal Priti , Simon M. Celeste
Published: April 2023

PDF file 84K, Genomic loci and expression of miR-30c-2-3p and miR-30a-3p in ccRCCs