bluuebunny/crossref_metadata_2025 huggingface dataset:
Peanut Aflatoxin: Impact of Postharvest Insect Infestation and Storage Systems
Authors: Mbata George N. , Danso James K. , Holton Raegan L.
Published: October 2024

Effective postharvest management is crucial for the U.S. peanut industry, given the humid-subtropical climate that promotes insect pests, Aspergillus mold, and aflatoxin contamination in peanut-producing states. This study surveyed five conventional metal warehouses (CMWs) and thirteen flat storage facilities (FSFs) in northeastern, southeastern, and southwestern Georgia, USA, from December 2022 to July 2023. Peanuts were sampled monthly to assess the temporal abundance and diversity of storage insect pests, damage variables, and aflatoxin levels in farmers’ stock peanuts. A monoclonal antibody-based affinity chromatographic assay determined the total aflatoxin levels in samples. The most common insect species, accounting for ~85.73 of the total captured, included Cryptolestes ferrugineus, Tribolium castaneum, Ahasverus advena, Plodia interpunctella, Cadra cautella, Ephestia elutella, Liposcelis spp., and Lachesilla pedicularia. Insect populations peaked in June and July, with similar diversity trends across CMWs and FSFs. Insect-damaged kernels, weight loss, discolored kernels, loose-shelled kernels, moisture content, and aflatoxin levels ranged from 3.02 to 11.45%, 1.11 to 3.60%, 2.11 to 11.20%, 1.56 to 4.91%, 6.89 to 8.85%, and 0.43 to 27.59 ppb, respectively. The high prevalence of insect pests, their damage capabilities, and the aflatoxin levels of infested peanuts highlight the need for an improved IPM strategy in warehouses to ensure safe and sustainable peanut storage in the USA.
Integrated Biological Control Strategies for Citrus Rust Mites: Distribution, Impact on Mandarin Quality, and the Efficacy of Amblyseius largoensis
Authors: Mahmood Syed Usman , Huang Xiaoyi , Mao Runqian , Hao Huihua , Fang Xiaoduan
Published: October 2024

Citrus rust mites (Phyllocoptruta oleivora Ashmead) are a major pest in citrus orchards, significantly affecting fruit quality and yield. Effective management of these mites is crucial for maintaining the economic viability of citrus production. This study investigated the ecological distribution of citrus rust mites and their natural predator, A. largoensis, in a mandarin orchard in Zengcheng District, Guangzhou City, of China. This research focused on population densities across different orchard sections and assessed the impact of mite infestations on the biochemical composition of mandarins, including vitamin C, soluble solids, acidity, and mineral content. Results showed that citrus rust mite populations were highest in the southern and western sections of the orchard. Infested fruits had reduced vitamin C and soluble solids but increased acidity and calcium levels. A. largoensis exhibited a strong functional (Type II) and numerical response, with higher predation rates and reproductive output for moderate prey densities. The findings emphasize the importance of targeted pest management strategies in citrus rust mite hotspots and highlight A. largoensis as a promising biological control agent. Future research should optimize its use in integrated pest management programs by focusing on areas of the orchard with high mite densities.
Early Diagnosis of Huntington Disease: Insights from Magnetic Resonance Spectroscopy—A Systematic Review
Authors: Martínez Lozada Pablo S. , Duque Perez José , Celi Salinas Ronney , Miranda Morales Bryan , Pazmiño Mesías Juan Francisco , García Ríos Cecilia Alejandra , Rodas Jose A. , Leon-Rojas Jose E.
Published: October 2024

Background/Objectives: Huntington’s disease (HD) is a fully penetrant neurodegenerative disease with a profound effect on quality of life. In recent years, there has been rapid growth in the description of its pathogenesis and diagnosis. Magnetic resonance spectroscopy (MRS) measurements can aid in the discrimination between premanifest Huntington’s disease (Pre-HD) and healthy control (HC) subjects to establish early supportive and symptomatic management. Our objective was to evaluate metabolic changes using MRS to shed light on its potential as a biomarker through a systematic review. Methods: We followed the PRISMA guidelines, extracting articles from PubMed, Scopus, and the Virtual Health Library. We included patients with pre-HD, HD, and HC subjected to MRS, reporting the concentration of metabolites in at least one brain region. Results: In the putamen, N-acetyl Aspartate (NAA) was significantly decreased in 77.9% and total NAA (tNAA) was decreased in 72.4% of cases; no significant difference was found in 27.5% (n = 19) of cases. Furthermore, when looking into HD vs. pre-HD in the putamen, tNAA and NAA were decreased in 100% of participants. In the caudate nucleus, NAA and creatine were significantly decreased in 100% of HD in comparison to pre-HD participants, whereas tNAA showed a significant decrease in only 50%. Conclusions: MRS can be a relevant tool for the early diagnosis of HD; potential objective biomarkers related to its onset and pathogenesis exist and show differences between controls, pre-HD and HD patients. However, an effort should be made to standardize MRS methodology and reporting in subsequent studies.
Efficacy and Safety of Cardioband in Patients with Tricuspid Regurgitation: Systematic Review and Meta-Analysis of Single-Arm Trials and Observational Studies
Authors: Piragine Eugenia , Veneziano Sara , Trippoli Sabrina , Messori Andrea , Calderone Vincenzo
Published: October 2024

Background/Objectives: The incidence and prevalence of tricuspid regurgitation (TR) are increasing worldwide. “Traditional” drug therapy with diuretics is often ineffective and the identification of new strategies, including non-pharmacological ones, is an urgent need. The aim of this study was to summarize the results on the efficacy and safety of Cardioband, one of the few approved transcatheter tricuspid valve repair systems, in patients with TR. Methods: Three databases (Medline, Scopus, and CENTRAL) were searched to identify clinical trials and observational studies on the efficacy (primary outcome) and safety (secondary outcome) of Cardioband. A random-effects meta-analysis was performed with R software (version 4.3.3). Survival and freedom from heart failure (HF) hospitalization were estimated with the method of reconstructing individual patient data from Kaplan–Meier curves (IPDfromKM). Results: Eleven studies were included in this systematic review and meta-analysis. Cardioband significantly reduced annulus diameter (−9.31 mm [95% Confidence Interval, CI: −11.47; −7.15]), vena contracta (−6.41 mm [95% CI: −8.34; −4.49]), and effective regurgitant orifice area (EROA) (−0.50 cm2 [95% CI: −0.72; −0.28]) in patients with TR. Cardioband reduced the severity of TR and the extent of heart failure in 91% [95% CI: 85; 97] and 63% [95% CI: 52–75] of patients, respectively. Finally, Cardioband implantation was associated with prolonged survival and freedom from HF hospitalization (80.1% and 57.8% at 24 months, respectively). Conclusions: This study demonstrates that Cardioband implantation leads to cardiac remodeling and mechanical improvements, reduces the severity of TR, and improves quality of life. Therefore, Cardioband is an effective option for the non-pharmacological treatment of TR.
Finerenone: A Third-Generation MRA and Its Impact on Cardiovascular Health—Insights from Randomized Controlled Trials
Authors: Sabina Michael , Trube Jennifer , Shah Shrinand , Lurie Andrew , Grimm Mason , Bizanti Anas
Published: October 2024

Introduction: Finerenone, a third-generation non-steroidal mineralocorticoid receptor antagonist (MRA), offers a targeted approach to managing cardiovascular outcomes, particularly in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D). Unlike traditional MRAs such as spironolactone and eplerenone, which can cause off-target hormonal side effects and hyperkalemia, Finerenone selectively binds to mineralocorticoid receptors, reducing these risks. Recent randomized controlled trials have demonstrated Finerenone’s potential to improve cardiovascular outcomes, making it a promising alternative in the management of heart failure and other cardiovascular conditions associated with CKD and T2D. Methods: We conducted a scoping review using PRISMA guidelines. A search for “Finerenone” in the PubMed, Embase, and Cochrane Library databases included randomized controlled trials (RCTs), post hoc analyses, and relevant meta-analyses on cardiovascular outcomes. Data were synthesized narratively, assessing study quality through strengths and limitations. Discussion: Finerenone has shown significant benefits and a superior safety profile compared with traditional MRAs like spironolactone and eplerenone in managing CKD, T2D, and heart failure. It effectively reduces cardiovascular and renal events while minimizing risks such as hyperkalemia and hormonal side effects associated with steroidal MRAs. Future studies, including the REDEFINE-HF, FINALITY-HF, and CONFIRMATION-HF trials, will further explore Finerenone’s potential across diverse heart failure phenotypes, including its role in heart failure with mildly reduced and preserved ejection fractions, potentially establishing it as a cornerstone therapy in heart failure management. Conclusions: Finerenone represents a significant advancement in MRA therapy, offering enhanced safety and efficacy in managing cardiovascular outcomes in CKD and T2D patients. The current evidence supports its use as a promising alternative to traditional MRAs, particularly in patients intolerant to steroidal MRAs. Further trials are needed to fully establish its potential across diverse patient populations, including those with varying heart failure phenotypes.
Oldie but Goldie: The Fundamental Role of Radioiodine in the Management of Thyroid Cancer
Authors: Campennì Alfredo , Siracusa Massimiliano , Ruggeri Rosaria Maddalena
Published: October 2024

Background/Objectives: The management of differentiated thyroid cancer (DTC) patients has undergone a major paradigm shift in past years, especially regarding the role of a careful postoperative disease assessment both in deciding for or against the use of iodine-131 therapy (i.e., patients’ selection) and in selecting the correct goal of the treatment: ablative, adjuvant or therapeutic. Furthermore, diagnostic and risk-oriented uses of iodine isotopes (i.e., 123/124/131I) should always be considered during both postoperative assessment and follow-up of DTC patients to improve early staging and response assessment to initial treatments, respectively. The present review summarizes current (and real-life-related) evidence and the emerging perspectives on the therapeutic, diagnostic, and theragnostic use of radioiodine isotopes. Methods: A review of the pertinent literature was performed in PubMed, Web of Science, and Scopus without language restrictions or time limits and using one or more fitting search criteria and terms. Results: According to the literature evidence and real-life clinical practice, a risk-oriented postoperative iodine-131 therapy remains pivotal for most DTC patients and improves early disease staging through post-therapy functional imaging (i.e., theragnostic aim). Accordingly, the goal of iodine-131 therapy, the optimal strategy (empiric vs. dosimetric approach), the appropriate stimulation method [i.e., levothyroxine (L-T4) withdrawal vs. recombinant human thyrotropin (rhTSH) administration] and, finally, the suggested radioiodine activity to deliver for iodine-131 therapy (RIT) should be personalized, especially in metastatic DTC patients. Conclusions: The evidence related to the diagnostic and theragnostic use of iodine isotopes leads to a significant improvement in the postoperative risk stratification and staging of DTC patients in addition to a more accurate assessment of the response to initial treatments. In conclusion, radioiodine is really an oldie but goldie radiotracer. It has both a current fundamental role and a future perspective for the more careful management of DTC patients.
Psoriasis in Childbearing Age: A Real-Life, Retrospective, Single-Center Study on Anti-IL17 and IL-23 Agents
Authors: Borriello Silvia , Roccuzzo Gabriele , Dapavo Paolo , Sciamarrelli Nadia , Macagno Nicole , Leo Francesco , Quaglino Pietro , Ribero Simone , Mastorino Luca
Published: October 2024

Background: Psoriasis (PSO) involves about 1–3% of the population, and around 75% of women develop PSO before the age of 40. Official guidelines on the treatment of woman with anti-IL17 and anti-IL23 during this potential childbearing time are not currently available. Objective: To investigate the effectiveness and safety of biologic treatments in women of childbearing age. Methods: At the Dermatology Clinic of the University of Turin, Italy, 172 women aged 20–55 years underwent IL-17 and IL-23 inhibitor therapy for moderate-severe PSO and were followed up to 52 weeks in a real-life, retrospective, single-center study. Results: Overall, 40% of patients achieved PASI 100 at week 16, and 72% at week 52. A similar trend was observed for PASI 90 and PASI < 3 with almost 80% and 90% of patients achieving the target at 52 weeks. As for PASI 100, a statistically significant difference (p = 0.004) was found at 16 weeks, with 23.84% of patients achieving PASI 100, with IL-17 and 15.70% with the IL-23 inhibitor. No statistically significant differences were found at 28 and 52 weeks. No statistically significant differences in PASIs at any time points were recorded across the different biologic agents. Forty-six patients discontinued treatment. The most reported side effects were headache, nausea, asthenia, injection site pain, and rhinitis. Conclusions: This study showed that biologic drugs are effective and safe in women of childbearing age, with negligible side effects.
Medication Burden Before and After Prescription of Biologics in Patients with Inflammatory Bowel Disease
Authors: Fernandez Milano Annika , Krieg Sarah , Kostev Karel
Published: October 2024

Background: Biologics are a cornerstone in the treatment of severe cases of inflammatory bowel disease (IBD) and aim to control the disease and improve quality of life. This study investigated changes in nonbiologic medication prescriptions for IBD patients initiating biologic therapy in Germany. Methods: This study used data from anonymized pharmacy records in the German longitudinal prescription (LRx) database and included biologic-naive IBD patients who received their first biologic therapy prescription between 2016 and 2022. Changes in prescription rates and pill counts for nonbiologic medications (corticosteroids, 5-aminosalicylates (5-ASA), proton pump inhibitors, analgesics, immunosuppressants, Vitamin D, iron, and antibiotics) before and after the initiation of biologic therapy were assessed using descriptive statistics, McNemar’s tests, and Poisson regression models, adjusting for age and sex. Results: A total of 29,559 biologic-naive IBD patients were included. Prior to index, 91.2% received at least one nonbiologic medication prescription, where corticosteroids and 5-ASA were the most common. Postindex, the overall prescription rate decreased to 87.7%, with significant reductions in prescriptions observed for corticosteroids, 5-ASA, and immunosuppressants (p-values < 0.001). The mean (SD) pill count dropped from 704 (1712) to 514 (1651), with the largest mean differences (95% CI) having been for corticosteroids (−77.9 [−80.3 to −75.5]), 5-ASA (−61.6 [−65.2 to −58.1]), and immunosuppressants (−55.0 [−57.5 to −52.6]). Older patients tended to have greater decreases in pill counts for corticosteroids and 5-ASA, while males showed statistically significant reductions in pill count for immunosuppressants compared with females. Conclusions: This study demonstrates that the prescription of nonbiologic medications significantly decreased after biologic therapy initiation. The use of biologics may therefore lead to improved disease management and potentially better patient outcomes.
Effect of Vestibular Stimulation on Balance and Gait in Parkinson’s Disease: A Systematic Review
Authors: Iravani-Naeeni Ardavan , Mohagheghi Amir
Published: October 2024

Background/Objectives: Parkinson’s Disease (PD) can be associated with balance and gait impairments leading to increased risk of falls. Several studies have reported positive effects of various forms of vestibular stimulation (VS) for improving balance and stability in people with PD (PwP). The purpose of present study was to synthesise the current evidence on the effectiveness of VS, highlighting its potential benefits in improving postural stability and reducing gait impairments in people with Parkinson’s Disease. Method: A systematic search was conducted across databases Cochrane, Medline, PEDro, PubMed, Web of Science, and Google Scholar. Studies were included if they involved PwP at stages 3 or 4 of the Hoehn and Yahr scale, aged 60 years or older. The Risk of Bias (RoB) was assessed using the ROBINS-I tool. The review followed the PRISMA guidelines and the protocol was registered with PROSPERO (CRD42022283898). Results: demonstrated that various forms of VS have shown promise in mitigating symptoms of vestibular dysfunction and improving gait and balance in PwP. However, the overall RoB ranged from moderate to critical, with variations across different domains. Conclusions: While VS appears to offer potential benefits in improving balance and gait in PwP, the presence of biases in the reviewed studies necessitate caution in interpreting the results. Further research should focus on addressing these biases to confirm the therapeutic potential of VS in PD.
The Internal Structure of the WISC-V in Chile: Exploratory and Confirmatory Factor Analyses of the 15 Subtests
Authors: Rodríguez-Cancino Marcela , Concha-Salgado Andrés
Published: October 2024

The WISC-V is a widely used scale in clinical and educational settings in Chile. Given that its use guides critical decision-making for children and adolescents, it is essential to have evidence of its psychometric properties, including validity based on internal structure. This study analyzed the factor structure of the WISC-V through an exploratory (EFA) and confirmatory (CFA) approach considering the age range of 853 children and adolescents between 6 and 16 years. We obtained evidence favoring the four-factor structure in the EFA, which is a clearer organization in the 15–16 age group. In the confirmatory stage, the best four- and five-factor models showed factor loadings greater than 0.4, except for one subtest in the processing speed domain in the 6–8 age group. The internal consistency ranged from acceptable to good estimates for the best two models. The results support the use of hierarchical factor structures of four and five factors, which offer specific advantages and disadvantages discussed in the article. The implications of these findings in both the professional area of psychology and future research are discussed.
Research on the Risk of Drilling Phases Based on the Development Model of Shallow-Water Subsea Trees
Authors: Yin Zhiming , Ren Meipeng , Ma Yingwen , Yang Xiangqian , Tian Deqiang , Wang Haiwei , Xiao Chengcheng , Qu Jingyu
Published: October 2024

China is actively advancing offshore oil and gas exploration and development, focusing on addressing the technical challenges associated with resource extraction in shallow waters. The shallow-water subsea tree development model has gradually been applied in such environments, alleviating some construction difficulties. However, it still poses well control risks that require systematic analysis and quantitative evaluation. Given that the blowout preventer (BOP) is located on the platform and the shallow-water subsea tree is only used during certain drilling stages, this study divided the drilling process into two phases: the first three sections and the fourth section. Based on the “man–machine–material–environment” analytical framework and an improved system-theoretic process analysis (STPA), a control model for the construction phases was developed. Fault tree analysis (FTA) was then employed to identify comprehensively the potential risks from the platform to the wellbore in both phases. Subsequently, the decision-making trial and evaluation laboratory (DEMATEL) method were used to assess quantitatively the well control risks. Using the average weight as the evaluation criterion, high-risk factors exceeding the average weight in each phase were identified. The results indicate that in the shallow-water subsea tree development model, well control risks in the first three drilling sections primarily stem from human errors and equipment failures, while risks in the fourth section are mainly caused by damage to the subsea tree itself. The identified risk factors provide a theoretical basis for enhancing well control safety management in the shallow-water subsea tree development model.
The Synergistic Effects of Incobotulinum Toxin and Physiotherapy in a Rare Case of Paraparesis in a 7-Year-Old Affected by Klippel–Feil Syndrome Related to an MYH3 Gene Mutation: A Case Report
Authors: Ranieri Maurizio , Riccardi Mariagrazia , Raele Maria Vittoria , Farì Giacomo , Megna Marisa , Marvulli Riccardo
Published: October 2024

Background: Klippel–Feil disease is a condition characterized by a defect in the spine, consisting of the fusion or non-separation of two or more vertebrae of the cervical tract. It affects 1 in every 50,000 newborns, and the pathogenesis remains unknown to date, although the role of certain genes that are involved in segmentation processes is being studied. A single case of a genetic Myosin Heavy Chain 3 (MYH3) mutation is described here. Affected patients are typically distinguished by a relatively short neck, which leads to limited mobility, a low hairline, and obesity; they may also experience various other health issues. The common occurrence of comorbidities further diminishes the quality of life of these young individuals. Methods: The following case report describes the synergistic effect of Incobotulinum toxin type A and physiotherapy in a 7-year-old patient with MYH3 mutation-related Klippel–Feil syndrome (KFS) complicated by bilateral paraplegia to improve the spasticity condition of the lower limbs. To assess improvements over time, the patient underwent rating scales to determine spasticity (Modified Ashworth Scale: MAS), the neck’s range of motion (ROM), and muscle tone by using MyotonPro®. Specifically, measurements were taken on the day of the first medical examination (T0), the month after the injection and the startup of therapeutic exercise (T1), at three months (T2), and then once a month for a total of 6 months (T3, T4, and T5). Results: This therapeutic approach resulted in highly satisfactory outcomes for the child’s well-being, which was maintained until the sixth month and was accompanied by a complete absence of any side effects.
Construction and Optimization of Ecological Security Patterns Based on Ecosystem Services in the Wuhan Metropolitan Area
Authors: Chen Beiling , Zhu Jianhua , Liu Huayan , Zeng Lixiong , Li Fuhua , Xiao Zhiyan , Xiao Wenfa
Published: October 2024

Rapid urbanization has affected ecosystem stability, and the construction of ecological security patterns (ESPs) can rationally allocate resources and achieve ecological protection. Priority evaluation of critical areas can maximize the benefits of ecological protection, which is crucial for sustainable urban development. However, most prior studies have focused on assessing individual elements of the ESP, rarely considering both the protection priority of ecological sources and corridors. We constructed ESPs for the Wuhan Metropolitan Area (WMA) from 2000 to 2020 and evaluated the priority of ecological sources and corridors for protection. The findings indicated that high-level ecological sources exhibited higher overall landscape connectivity and ecosystem service values with lower patch fragmentation. The average area proportions of primary, secondary, and tertiary ecological sources in 2000, 2010, and 2020 were 41.11%, 23.03%, and 29.86%, respectively. High-level ecological corridors had shorter lengths and offered higher comprehensive ecosystem service values. The total length of secondary corridors exceeded that of primary corridors by 1951.19 km, 650.39 km, and 2238.18 km in 2000, 2010, and 2020, respectively. Primary corridors, which connected fragmented and isolated sources, should have their ecological land percentage increased to enhance connectivity. Secondary corridors connected two independent and distant sources, providing the basis for ecological protection in the intervening area, whose surrounding habitats should be protected. This study identifies the ecological protection priority and offers a theoretical basis and practical reference for balancing urban development with ecological protection.
Feasibility of Low-Code Development Platforms in Precision Agriculture: Opportunities, Challenges, and Future Directions
Authors: Guresci Emin , Tekinerdogan Bedir , Babur Önder , Liu Qingzhi
Published: October 2024

Low-Code Development Platforms (LCDPs) empower users to create and deploy custom software with little to no programming. These platforms streamline development, offering benefits like faster time-to-market, reduced technical barriers, and broader participation in software creation, even for those without traditional coding skills. This study explores the application of LCDPs in Precision Agriculture (PA) through a systematic literature review (SLR). By analyzing the general characteristics and challenges of LCDPs, alongside insights from existing PA research, we assess their feasibility and potential impact in agricultural contexts. Our findings suggest that LCDPs can enable farmers and agricultural professionals to create tailored applications for real-time monitoring, data analysis, and automation, enhancing farming efficiency. However, challenges such as scalability, extensibility, data security, and integration with complex IoT systems must be addressed to fully realize the benefits of LCDPs in PA. This study contributes to the growing knowledge base in agricultural technology, offering valuable insights for researchers, practitioners, and policymakers looking to leverage LCDPs for sustainable and efficient farming practices.
Effect of Natural Inhibitors on the Corrosion Properties of Grade 2 Titanium Alloy
Authors: Faraji Mehrdad , Pezzato Luca , Yazdanpanah Arshad , Nardi Giacomo , Esmailzadeh Mojtaba , Calliari Irene
Published: October 2024

This study investigates the effects of natural inhibitors (pomegranate, algae, and tomato extracts) on the corrosion resistance of titanium (grade 2). To deepen understanding the inhibition mechanism, Molecular Dynamic (MD) and Monte Carlo (MC) simulations were employed to analyze adsorption behaviors and identify optimal adsorption sites on titanium oxide (TiO2) surfaces for compounds within the inhibitors. Results indicate non-flat adsorption orientations, with pomegranate peel extract components showing superior inhibition capabilities, attributed to the formation of strong O-H chemical bonds with the TiO2 surface. In the experimental part of the study Electrochemical Impedance Spectroscopy (EIS) and Potentiodynamic Polarization (PDP) were conducted. Two electrolytes were tested: a solution 3.5% NaCl and a solution 0.5 M NaOH. All the tests were performed with 5% of inhibitor and with the reference solution. Also, inhibition efficiency was calculated on the base of PDP tests. The study found that pomegranate extract can act as a good corrosion inhibitor for titanium alloy in aqueous solutions 0.5 M NaOH. This was demonstrated by the increase in the corrosion potential and impedance modulus and decrease in the corrosion current density after the addition of pomegranate extract to the solution. However, in a 3.5% NaCl solution, the efficacy of pomegranate extract was less pronounced, probably due to the high aggressivity of the electrolyte. Tomato and algae extract have instead shown very low inhibition effects in all the tested conditions.
Thinking Green on 3D Printing: Sustainable Polymer Compositions of Post-Consumer Polypropylene and Tire Rubber Crumbs Intended for Industrial Applications
Authors: Paszkiewicz Sandra , Andrzejewski Jacek , Grochała Daniel , Adamczyk Kamil , Figiel Paweł , Piesowicz Elżbieta , Pokwicka-Croucher Katarzyna
Published: October 2024

Year by year, more and more plastic is used worldwide. A large part of post-consumer waste is still stored in landfills instead of being reused. The solution to this problem may be recycled materials (recyclates) or biodegradable materials. The method of 3D printing, regarded as a clean processing technology, can significantly contribute to addressing global plastic pollution by utilizing post-consumer recycled polymers to create new components and parts. Therefore, this study focuses on the assessment of various properties and characteristics of 3D-printed compositions based on post-consumer polypropylene (PP) and rubber crumbs, recycled from packages foils and car tires, respectively. Moreover, within this study, we compared the mechanical performance of the injection molding material with the one obtained from 3D printing. A characterization was made considering the thermal and mechanical properties as well as the “print quality” through the microscopic and tomographic analysis of subsequent print passes, the number of free spaces, and imperfections in the polymer melt. Samples obtained using the FDM and injection methods exhibited comparable melting temperatures, while the samples obtained by injection molding exhibited slightly better mechanical performance, higher hardness, and impact strength.
A Novel Fourth-Order Finite Difference Scheme for European Option Pricing in the Time-Fractional Black–Scholes Model
Authors: Cai Xin , Wang Yihong
Published: October 2024

This paper addresses the valuation of European options, which involves the complex and unpredictable dynamics of fractal market fluctuations. These are modeled using the α-order time-fractional Black–Scholes equation, where the Caputo fractional derivative is applied with the parameter α ranging from 0 to 1. We introduce a novel, high-order numerical scheme specifically crafted to efficiently tackle the time-fractional Black–Scholes equation. The spatial discretization is handled by a tailored finite point scheme that leverages exponential basis functions, complemented by an L1-discretization technique for temporal progression. We have conducted a thorough investigation into the stability and convergence of our approach, confirming its unconditional stability and fourth-order spatial accuracy, along with (2−α)-order temporal accuracy. To substantiate our theoretical results and showcase the precision of our method, we present numerical examples that include solutions with known exact values. We then apply our methodology to price three types of European options within the framework of the time-fractional Black–Scholes model: (i) a European double barrier knock-out call option; (ii) a standard European call option; and (iii) a European put option. These case studies not only enhance our comprehension of the fractional derivative’s order on option pricing but also stimulate discussion on how different model parameters affect option values within the fractional framework.
Integrating Process Simulation and Life Cycle Assessment for Enhanced Process Efficiency and Reduced Environmental Impact in Ferromanganese Production
Authors: Larssen Trine A. , Canaguier Vincent , Reuter Markus A. , Ringdalen Eli
Published: October 2024

Process simulation was integrated with life cycle assessment to evaluate process efficiency and environmental impact of the production of manganese ferroalloys for various production modes and different ore mineralogies. Utilizing HSC Sim, the model was designed to evaluate the production process with or without a pretreatment step, where results for simulated cases using a four-zone ferromanganese furnace model were exported to openLCA for a complete life cycle assessment. Two main production scenarios were simulated: a closed ferromanganese furnace running on the duplex method and an open furnace running on the discard slag approach. The closed furnace scenario achieved a 17.5% reduction in energy consumption and a 16.2% decrease in direct CO2 emissions with CO-rich off-gas pretreatment. The open furnace scenario showed an 11.2% reduction in energy consumption with thermal solar energy pretreatment but no change in CO2 emissions.
Calibration of Heat Source Models in Numerical Simulations of Welding Processes
Authors: Kik Tomasz
Published: October 2024

This article presents issues related to the methodology of the correct definition of the heat source model in the numerical analyses of welding processes. The problem of determining the input data for the stage of a heat source model definition, obtaining input data from experiments, and their proper interpretation and use in defining the numerical model was discussed. Particular attention is paid to the specificity of the problem of defining the heat source model, the way of interpreting the results of the analyses and the way of comparing them with the results of real experiments. The basic problems related to the mapping of the complex geometry of the molten metal pool and the ways to solve them were indicated. The solutions and guidelines presented in the article allow to improve the accuracy and quality of the obtained results of numerical analyses, as well as to shorten the time of preparation of computational models by reducing the number of computational iterations related to the search for the maximum consistency of the compared values and temperature cycles.
High-Performance Triboelectric Nanogenerator with Double-Side Patterned Surfaces Prepared by CO2 Laser for Human Motion Energy Harvesting
Authors: Lin Dong-Yi , Chung Chen-Kuei
Published: October 2024

The triboelectric nanogenerator (TENG) has demonstrated exceptional efficiency in harvesting diverse forms of mechanical energy and converting it into electrical energy. This technology is particularly valuable for powering low-energy electronic devices and self-powered sensors. Most traditional TENGs use single-sided patterned friction pairs, which restrict their effective contact area and overall performance. Here, we propose a novel TENG that incorporates microwave patterned aluminum (MC-Al) foil and microcone structured polydimethylsiloxane (MC-PDMS). This innovative design utilizes two PMMA molds featuring identical micro-hole arrays ablated by a CO2 laser, making it both cost-effective and easy to fabricate. A novel room imprinting technique has been employed to create the micromorphology of aluminum (Al) foil using the PMMA mold with shallower micro-hole arrays. Compared to TENGs with flat friction layers and single-side-patterned friction layers, the double-side-patterned MW-MC-TENG demonstrates superior output performance due to increased cone deformation and contact area. The open-circuit voltage of the MW-MC-TENG can reach 141 V, while the short-circuit current can attain 71.5 μA, corresponding to a current density of 2.86 µA/cm2. The power density reaches 1.4 mW/cm2 when the resistance is 15 MΩ, and it can charge a 0.1 μF capacitor to 2.01 V in 2.28 s. In addition, the MW-MC-TENG can function as an insole device to harvest walking energy, power 11 LED bulbs, monitor step speed, and power a timer device. Therefore, the MW-MC-TENG has significant application potential in micro-wearable devices.
Recent Trends in the Production and Recovery of Bioplastics Using Polyhydroxyalkanoates Copolymers
Authors: García Andrés , Aguirre Claudia , Pérez Andrés , Bahamonde Sofía S. , Urtuvia Viviana , Díaz-Barrera Alvaro , Peña Carlos
Published: October 2024

Polyhydroxyalkanoates (PHAs) are polyesters synthesized as a carbon and energy reserve material by a wide number of bacteria. These polymers are characterized by their thermoplastic properties similar to those of plastics derived from the petrochemical industry, such as polyethylene and polypropylene. PHAs are widely used in the medical field and have the potential to be used in other applications due to their biocompatibility and biodegradability. Among PHAs, P(3HB-co-3HV) copolymers are thermo-elastomeric polyesters that are typically soft and flexible with low to no crystallinity, which can expand the range of applications of these bioplastics. Several bacterial species, such as Cupriavidus necator, Azotobacter vinelandii, Halomonas sp. and Bacillus megaterium, have been successfully used for P(3HB-co-3HV) production, both in batch and fed-batch cultures using different low-cost substrates, such as vegetable and fruit waste. Nevertheless, in recent years, several fermentation strategies using other microbial models, such as methanotrophic bacterial strains as well as halophilic bacteria, have been developed in order to improve PHA production in cultivation conditions that are easily implemented on a large scale. This review aims to summarize the recent trends in the production and recovery of PHA copolymers by fermentation, including different cultivation modalities, low-cost raw materials, as well as downstream strategies that have recently been developed with the purpose of producing copolymers, such as P(3HB-co-3HV), with suitable mechanical properties for applications in the biomedical field.
Two Sporadic Cases of Legionellosis Associated with the Use of Domestic Ultrasonic Humidifiers
Authors: Reinares Ortiz Javier , Pérez-Serrano Jorge , González-Rubio Juana María , González-Camacho Fernando
Published: October 2024

Two sporadic cases of legionellosis occurring in consecutive years were confirmed by positive antigenuria to Legionella pneumophila serogroup 1 in individuals with limited mobility who were confined to their homes. Both cases had a history of using ultrasonic humidifiers and of low exposure to other possible sources of infection. This study was conducted through an expanded epidemiological survey and home inspection. Samples were collected from domestic hot water and humidifiers. Environmental isolates were characterised by immunoagglutination and immunofluorescence. The Dresden panel is employed for the determination of groups and subgroups of serogroup 1. The amoebae were isolated by water filtration and subsequent cultivation of the filters. Identification of the isolates was conducted through the sequencing of PCR products. In both cases, epidemiological studies identified the ultrasonic humidifiers as the probable source of infection. The presence of Legionella pneumophila was confirmed in the sanitary water installation and in the humidifiers, where high values of Legionella pneumophila serogroup 1 counts were also obtained. The isolates were characterised as Olda Oxford and Olda OLDA. Furthermore, in addition to the Legionella isolates, the presence of Vermamoeba vermiformis was also identified in samples obtained from domestic hot water and humidifiers in one of the residential addresses under investigation. It has been demonstrated that humidifiers can act as an amplification mechanism for pathogenic microorganisms when they are not cleaned and maintained correctly. This can pose a health danger, especially to people with previous respiratory pathologies, the immunosuppressed, and the elderly. Therefore, it is of the utmost importance that professionals who recommend the therapeutic use of this equipment should issue warnings regarding the importance of its correct use, cleaning, and disinfection. Finally, humidifiers should be considered in epidemiological surveys and in the study of sporadic cases.
Effects of Selenium Application on Fermentation Quality, Chemical Composition, and Bacterial Community of Hybrid Pennisetum Silage
Authors: Chen Xinzhu , Qiu Shuiling , Huang Liang , Yang Yanie , Huang Xiaoyun , Huang Xiusheng , Feng Deqing
Published: October 2024

The primary objective of this study is to facilitate the conversion of inorganic selenium (Se) into organic Se within plants via assimilation, subsequently feeding it to livestock and poultry to enhance healthy animal production and yield Se-enriched livestock and poultry products. Therefore, it is imperative to first investigate the impact of varying Se doses on the agronomic traits of plants as well as their forage storage and processing. This experiment investigated the effect of Se fertilizer application on the fermentation quality, chemical composition, and bacterial community of Pennisetum americanum × Pennisetum purpureum cv Minmu 7 (HPM7). There were nine Se fertilizer dissolution levels of HPM7 treated, which were 0 mg/kg (Se0), 0.50 mg/kg (Se1), 1.00 mg/kg (Se2), 2.00 mg/kg (Se3), 5.00 mg/kg (Se4), 10.00 mg/kg (Se5), 20.00 mg/kg (Se6), 30.00 mg/kg (Se7), 40.00 mg/kg (Se8), and 50.00 mg/kg (Se9). The results showed that after silage, the water-soluble carbohydrates of Se1, Se2, and Se3 were lower than Se0, and the pH of Se3, Se4, and Se6 were lower than the Se0. The number of OTUs in the nine groups was sequentially Se1 > Se2 > Se3 > Se8 > Se6 > Se5 > Se7 > Se4 > Se0. The dominant bacterial phyla in silage samples were Firmicutes and Proteobacteria. Compared with Se0, Bacterial Shannon index in Se1 and Se2 were higher, while Chao1 and ACE indices of Se1, Se2, Se3, Se5, and Se6 were higher. A beta diversity analysis indicated that the Se1 exhibited the highest number of significant biomarkers. Escherichia coli between Se0 and Se3 and Clostridium sardiniense and Clostridium perfringens between Se0 and Se1 exhibited significant differences at a species level. The most abundant pathways for metabolism were membrane transport, carbohydrate metabolism, translation, replication, repair, and amino acid metabolism. The correlation analysis indicated that the dry matter content was negatively correlated with Bacillus (p < 0.01), Lactobacillus (p < 0.05), Pediococcus (p < 0.05), and Hirschia (p < 0.05); the contents of neutral detergent fiber and hemi-cellulose were positively correlated with Lactobacillus (p < 0.05, p < 0.01). The protein content was negatively correlated with proteus (p < 0.05). This study demonstrated that the application of Se fertilizer could enhance the Se content in HPM7. The optimal fertilization concentration was found to range from 0.50 to 2.00 mg/kg, which facilitates the metabolism of soluble carbohydrates and enhances both the fermentation quality and microbial relative abundance of HPM7 silage.
Probiotic Mixtures Consisting of Representatives of Bacteroidetes and Selenomonadales Increase Resistance of Newly Hatched Chicks to Salmonella Enteritidis Infection
Authors: Volf Jiri , Faldynova Marcela , Matiasovicova Jitka , Sebkova Alena , Karasova Daniela , Prikrylova Hana , Havlickova Hana , Rychlik Ivan
Published: October 2024

There are extensive differences in the caecal microbiota of chicks from hatcheries and those inoculated with faecal material from adult hens. Besides differences in microbial composition, the latter chickens are highly resistant to Salmonella Enteritidis challenges, while the former are susceptible. In this study, we tested whether strains from genera Bacteroides, Megamonas, or Megasphaera can increase chicken resistance to Salmonella and Campylobacter jejuni when defined microbial mixtures consisting of these bacterial genera are administered. Mixtures consisting of different species and strains from the above-mentioned genera efficiently colonised the chicken caecum and increased chicken resistance to Salmonella by a factor of 50. The tested mixtures were even more effective in protecting chickens from Salmonella in a seeder model of infection (3–5 log reduction). The tested mixtures partially protected chickens from C. jejuni infection, though the effect was lower than that against Salmonella. The obtained data represent a first step for the development of a new type of probiotics for poultry.
How Gut Microbiome Perturbation Caused by Antibiotic Pre-Treatments Affected the Conjugative Transfer of Antimicrobial Resistance Genes
Authors: Yilmaz Gokhan , Chan Maria , Lau Calvin Ho-Fung , Capitani Sabrina , Kang Mingsong , Charron Philippe , Hoover Emily , Topp Edward , Guan Jiewen
Published: October 2024

The global spread of antimicrobial resistance genes (ARGs) poses a significant threat to public health. While antibiotics effectively treat bacterial infections, they can also induce gut dysbiosis, the severity of which varies depending on the specific antibiotic treatment used. However, it remains unclear how gut dysbiosis affects the mobility and dynamics of ARGs. To address this, mice were pre-treated with streptomycin, ampicillin, or sulfamethazine, and then orally inoculated with Salmonella enterica serovar Typhimurium and S. Heidelberg carrying a multi-drug resistance IncA/C plasmid. The streptomycin pre-treatment caused severe microbiome perturbation, promoting the high-density colonization of S. Heidelberg and S. Typhimurium, and enabling an IncA/C transfer from S. Heidelberg to S. Typhimurium and a commensal Escherichia coli. The ampicillin pre-treatment induced moderate microbiome perturbation, supporting only S. Heidelberg colonization and the IncA/C transfer to commensal E. coli. The sulfamethazine pre-treatment led to mild microbiome perturbation, favoring neither Salmonella spp. colonization nor a conjugative plasmid transfer. The degree of gut dysbiosis also influenced the enrichment or depletion of the ARGs associated with mobile plasmids or core commensal bacteria, respectively. These findings underscore the significance of pre-existing gut dysbiosis induced by various antibiotic treatments on ARG dissemination and may inform prudent antibiotic use practices.
Gypsum Crystals Formed by the Anhydrite–Gypsum Transformation at Low Temperatures: Implications for the Formation of the Geode of Pulpí
Authors: Cotellucci Andrea , Garcia-Ruiz Juan-Manuel , Otálora Fermín , Canals Àngels , Bruno Marco , Wehrung Quentin , Pellegrino Luca , Aquilano Dino , Pastero Linda
Published: October 2024

Determining the mechanisms of the formation of giant crystals is a challenging subject. Gypsum, calcium sulfate dihydrate (CaSO4·2H2O), is known to form crystals larger than one meter in several locations worldwide. These selenite crystals grow at different temperatures, either in sedimentary or hydrothermal systems. The famous selenite crystals of the geode of Pulpí (Almería, Spain) are known to have grown at a temperature T = 20 ± 5 °C and have been proposed to form in a subaqueous environment by a self-feeding mechanism triggered by anhydrite dissolution and the ripening of microcrystalline gypsum, enhanced by oscillations in temperature. This paper reports the monitored crystallization of gypsum crystals, from anhydrite powder dissolution, inside airtight evaporation-free reactors under oscillating low temperatures (15 °C < T < 25 °C). These crystals are clearly smaller than the ones in the Pulpí mine but exhibit similar habits (i.e., single blocky crystals and twins following the 100 twinning law). The growth rate of gypsum single crystals has been measured to be between 3.8 and 35.3 µm/day. Noteworthy, we document the occurrence of the 100 contact twinning law of gypsum, which is the most widespread twinning law in natural environments but never univocally reported in laboratory experiments. The selection of the 100 contact twinning law has been correlated to the low supersaturation values obtained in the experiment, where the concentration in these long-duration experiments can be safely assumed to be the equilibrium concentration, i.e., 0.3 (at 25 °C) ≤ SI ≤ 0.4 (at 15 °C). We discuss the relevance of our experiment for forming the gypsum crystals of Pulpí in the framework of the geological history of Pulpí mineralization. These laboratory model experiments contribute to a deeper understanding of mineral nucleation and growth processes in natural environments.