bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S1 from PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates
Authors: Veach Darren R. , Storey Claire M. , Lückerath Katharina , Braun Katharina , von Bodman Christian , Lamminmäki Urpo , Kalidindi Teja , Strand Sven-Erik , Strand Joanna , Altai Mohamed , Damoiseaux Robert , Zanzonico Pat , Benabdallah Nadia , Pankov Dmitry , Scher Howard I. , Scardino Peter , Larson Steven M. , Lilja Hans , McDevitt Michael R. , Thorek Daniel L.J. , Ulmert David
Published: April 2023

Supplementary Figure S1. Ex-vivo biodistribution of [89Zr]hu5A10.
Table S1 from An Open-Source, Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Triple-Negative Breast Cancer
Authors: Bai Yalai , Cole Kimberly , Martinez-Morilla Sandra , Ahmed Fahad Shabbir , Zugazagoitia Jon , Staaf Johan , Bosch Ana , Ehinger Anna , Nimeus Emma , Hartman Johan , Acs Balazs , Rimm David L.
Published: April 2023

Fold redundancy of TMA sets
Supplementary Data from Clinical and Immunologic Responses to a B-Cell Epitope Vaccine in Patients with HER2/neu-Overexpressing Advanced Gastric Cancer—Results from Phase Ib Trial IMU.ACS.001
Authors: Wiedermann Ursula , Garner-Spitzer Erika , Chao Yee , Maglakelidze Marina , Bulat Iurie , Dechaphunkul Arunee , Arpornwirat Wichit , Charoentum Chaiyut , Yen Chia-Jui , Yau Thomas Cheung , Tanasanvimon Suebpong , Maneechavakajorn Jedzada , Sookprasert Aumkhae , Bai Li-Yuan , Chou Wen-Chi , Ungtrakul Teerapat , Drinic Mirjana , Tobias Joshua , Zielinski Christoph C. , Chong Leslie , Ede Nicholas J. , Marino Mark T. , Good Anthony J.
Published: April 2023

Supp. Fig 1 A-C; Supp. Fig 2 A-I; Supp. Fig 3 A, B; Supp. Fig 4, Supp. fig 5 A, B; Supp. Fig 6 A, B
Supplementary Data from Clinical and Immunologic Responses to a B-Cell Epitope Vaccine in Patients with HER2/neu-Overexpressing Advanced Gastric Cancer—Results from Phase Ib Trial IMU.ACS.001
Authors: Wiedermann Ursula , Garner-Spitzer Erika , Chao Yee , Maglakelidze Marina , Bulat Iurie , Dechaphunkul Arunee , Arpornwirat Wichit , Charoentum Chaiyut , Yen Chia-Jui , Yau Thomas Cheung , Tanasanvimon Suebpong , Maneechavakajorn Jedzada , Sookprasert Aumkhae , Bai Li-Yuan , Chou Wen-Chi , Ungtrakul Teerapat , Drinic Mirjana , Tobias Joshua , Zielinski Christoph C. , Chong Leslie , Ede Nicholas J. , Marino Mark T. , Good Anthony J.
Published: April 2023

Supp. Table 1; Supp. Table 2; Supp. Table 3 A,B; Supp. Table 4; Supp. Table 5; Supp. Table 6; Supplementary Data 1; Supplementary Data 2
Supplementary Table S6, from A Novel Topical Fluorescent Probe for Detection of Glioblastoma
Authors: Kitagawa Yosuke , Tanaka Shota , Kamiya Mako , Kuriki Yugo , Yamamoto Kyoko , Shimizu Takenori , Nejo Takahide , Hana Taijun , Matsuura Reiko , Koike Tsukasa , Yamazawa Erika , Kushihara Yoshihiro , Takahashi Satoshi , Nomura Masashi , Takami Hirokazu , Takayanagi Shunsaku , Mukasa Akitake , Urano Yasuteru , Saito Nobuhito
Published: April 2023

Real time PCR original data of U87 knocked down by siRNA
Supplementary Table S4, from A Novel Topical Fluorescent Probe for Detection of Glioblastoma
Authors: Kitagawa Yosuke , Tanaka Shota , Kamiya Mako , Kuriki Yugo , Yamamoto Kyoko , Shimizu Takenori , Nejo Takahide , Hana Taijun , Matsuura Reiko , Koike Tsukasa , Yamazawa Erika , Kushihara Yoshihiro , Takahashi Satoshi , Nomura Masashi , Takami Hirokazu , Takayanagi Shunsaku , Mukasa Akitake , Urano Yasuteru , Saito Nobuhito
Published: April 2023

All listed proteins for diced electrophoresis gel assay
Supplementary Data from A Novel Topical Fluorescent Probe for Detection of Glioblastoma
Authors: Kitagawa Yosuke , Tanaka Shota , Kamiya Mako , Kuriki Yugo , Yamamoto Kyoko , Shimizu Takenori , Nejo Takahide , Hana Taijun , Matsuura Reiko , Koike Tsukasa , Yamazawa Erika , Kushihara Yoshihiro , Takahashi Satoshi , Nomura Masashi , Takami Hirokazu , Takayanagi Shunsaku , Mukasa Akitake , Urano Yasuteru , Saito Nobuhito
Published: April 2023

All the supplementary materials except for supplementary table S4-S6
Supplementary Figures from BRCA2, ATM, and CDK12 Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression
Authors: Warner Evan , Herberts Cameron , Fu Simon , Yip Steven , Wong Amanda , Wang Gang , Ritch Elie , Murtha Andrew J. , Vandekerkhove Gillian , Fonseca Nicolette M. , Angeles Arkhjamil , Beigi Arshia , Schönlau Elena , Beja Kevin , Annala Matti , Khalaf Daniel , Chi Kim N. , Wyatt Alexander W.
Published: April 2023

Supplementary Figures S1-S6
Supplementary Data from Clinical Impact of Detecting Low-Frequency Variants in Cell-Free DNA on Treatment of Castration-Resistant Prostate Cancer
Authors: Mizuno Kei , Sumiyoshi Takayuki , Okegawa Takatsugu , Terada Naoki , Ishitoya Satoshi , Miyazaki Yu , Kojima Takahiro , Katayama Hiromichi , Fujimoto Naohiro , Hatakeyama Shingo , Shiota Masaki , Yoshimura Koji , Matsui Yoshiyuki , Narita Shintaro , Matsumoto Hiroaki , Kurahashi Ryoma , Kanno Hidenori , Ito Katsuhiro , Kimura Hiroko , Kamiyama Yuki , Sunada Takuro , Goto Takayuki , Kobayashi Takashi , Yamada Hitoshi , Tsuchiya Norihiko , Kamba Tomomi , Matsuyama Hideyasu , Habuchi Tomonori , Eto Masatoshi , Ohyama Chikara , Ito Akihiro , Nishiyama Hiroyuki , Okuno Hiroshi , Kamoto Toshiyuki , Fujimoto Akihiro , Ogawa Osamu , Akamatsu Shusuke
Published: April 2023

Supplementary Data includes Supplementary Methods, Supplementary Results, Supplementary Table S1-S13, Supplementary Figure S1-S7, and Supplementary References.
Assay of Serum Calcitonin from Anlotinib in Locally Advanced or Metastatic Medullary Thyroid Carcinoma: A Randomized, Double-Blind Phase IIB Trial
Authors: Li Dapeng , Chi Yihebali , Chen Xiaohong , Ge Minghua , Zhang Yuan , Guo Zhuming , Wang Jun , Chen Jie , Zhang Jiewu , Cheng Ying , Li Zhendong , Liu Hui , Qin Jianwu , Zhu Jingqiang , Cheng Ruochuan , Xu Zhengang , Zheng Xiangqian , Tang Pingzhang , Gao Ming
Published: April 2023

Detailed assay method for calcitonin
Supplementary Table 5 from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases
Authors: Smalley Inna , Chen Zhihua , Phadke Manali , Li Jiannong , Yu Xiaoqing , Wyatt Clayton , Evernden Brittany , Messina Jane L. , Sarnaik Amod , Sondak Vernon K. , Zhang Chaomei , Law Vincent , Tran Nam , Etame Arnold , Macaulay Robert J.B. , Eroglu Zeynep , Forsyth Peter A. , Rodriguez Paulo C. , Chen Y. Ann , Smalley Keiran S.M.
Published: April 2023

Supplemental Table 5: Cox proportional hazard model analysis identifies immune cell subpopulations associated with better survival outcomes
Supplementary Table 1 from Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types
Authors: van der Wijngaart Hanneke , Hoes Louisa R. , van Berge Henegouwen J. Maxime , van der Velden Daphne L. , Zeverijn Laurien J. , Roepman Paul , van Werkhoven Erik , de Leng Wendy W.J. , Jansen Anne M.L. , Mehra Niven , Robbrecht Debbie G.J. , Labots Mariette , de Groot Derk Jan A. , Hoeben Ann , Hamberg Paul , Gelderblom Hans , Voest Emile E. , Verheul Henk M.W.
Published: April 2023

Supplementary Table 1
Supplementary Table 4 from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases
Authors: Smalley Inna , Chen Zhihua , Phadke Manali , Li Jiannong , Yu Xiaoqing , Wyatt Clayton , Evernden Brittany , Messina Jane L. , Sarnaik Amod , Sondak Vernon K. , Zhang Chaomei , Law Vincent , Tran Nam , Etame Arnold , Macaulay Robert J.B. , Eroglu Zeynep , Forsyth Peter A. , Rodriguez Paulo C. , Chen Y. Ann , Smalley Keiran S.M.
Published: April 2023

Supplemental Table 4: top genes that differentiate each cluster of myeloid cells
Supplementary Table 3 from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases
Authors: Smalley Inna , Chen Zhihua , Phadke Manali , Li Jiannong , Yu Xiaoqing , Wyatt Clayton , Evernden Brittany , Messina Jane L. , Sarnaik Amod , Sondak Vernon K. , Zhang Chaomei , Law Vincent , Tran Nam , Etame Arnold , Macaulay Robert J.B. , Eroglu Zeynep , Forsyth Peter A. , Rodriguez Paulo C. , Chen Y. Ann , Smalley Keiran S.M.
Published: April 2023

Supplemental Table 3: top genes that differentiate each cluster of T/NK cells
Supplementary Figure 1 from Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types
Authors: van der Wijngaart Hanneke , Hoes Louisa R. , van Berge Henegouwen J. Maxime , van der Velden Daphne L. , Zeverijn Laurien J. , Roepman Paul , van Werkhoven Erik , de Leng Wendy W.J. , Jansen Anne M.L. , Mehra Niven , Robbrecht Debbie G.J. , Labots Mariette , de Groot Derk Jan A. , Hoeben Ann , Hamberg Paul , Gelderblom Hans , Voest Emile E. , Verheul Henk M.W.
Published: April 2023

Flow chart of patients with BRCA1/2 alterations submitted to the study team between September 2016 and December 2019, and reasons for drop-out, rejection or screen failure. Abbreviations: VUS = Variant of Unknown Significance, LOH = Loss of Heterozygosity.
Supplementary Table 1 from Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases
Authors: Smalley Inna , Chen Zhihua , Phadke Manali , Li Jiannong , Yu Xiaoqing , Wyatt Clayton , Evernden Brittany , Messina Jane L. , Sarnaik Amod , Sondak Vernon K. , Zhang Chaomei , Law Vincent , Tran Nam , Etame Arnold , Macaulay Robert J.B. , Eroglu Zeynep , Forsyth Peter A. , Rodriguez Paulo C. , Chen Y. Ann , Smalley Keiran S.M.
Published: April 2023

Supplemental Table 1: Flow Cytometry Antibodies
Supplementary Data from Independent Validation of the PAM50-Based Chemo-Endocrine Score (CES) in Hormone Receptor–Positive HER2-Positive Breast Cancer Treated with Neoadjuvant Anti–HER2-Based Therapy
Authors: Pascual Tomás , Fernandez-Martinez Aranzazu , Tanioka Maki , Dieci M. Vittoria , Pernas Sonia , Gavila Joaquin , Guarnieri Valentina , Cortes Javier , Villagrasa Patricia , Chic Núria , Vidal Maria , Adamo Barbara , Muñoz Montserrat , Griguolo Gaia , Llombart Antonio , Conte Pierfranco , Oliveira Mafalda , Conte Benedetta , Paré Laia , Galvan Patricia , Carey Lisa A. , Perou Charles M. , Prat Aleix
Published: April 2023

Supplementary Data
Supplementary Tables from Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer
Authors: De Angelis Carmine , Fu Xiaoyong , Cataldo Maria Letizia , Nardone Agostina , Pereira Resel , Veeraraghavan Jamunarani , Nanda Sarmistha , Qin Lanfang , Sethunath Vidyalakshmi , Wang Tao , Hilsenbeck Susan G. , Benelli Matteo , Migliaccio Ilenia , Guarducci Cristina , Malorni Luca , Litchfield Lacey M. , Liu Jiangang , Donaldson Joshua , Selenica Pier , Brown David N. , Weigelt Britta , Reis-Filho Jorge S. , Park Ben H. , Hurvitz Sara A. , Slamon Dennis J. , Rimawi Mothaffar F. , Jansen Valerie M. , Jeselsohn Rinath , Osborne C. Kent , Schiff Rachel
Published: April 2023

Supplementary Table S1. Details of antibodies used in this study. Supplementary Table S2. Q-PCR primers. Supplementary Table S3. HALLMARK gene-set enrichment analysis (GSEA) of baseline tumor samples from the NeoPalANA trial. Supplementary Table S4. Palbociclib IC50 values in MCF7 P, MCF7 EDR, T47D P-LM, and T47D EDR palbociclib-resistant (PalboR)-LM cell lines. Supplementary Table S5. Top-20 Gene Ontology (GO) terms significantly enriched in PalboR cell lines. Supplementary Table S6. HALLMARK gene sets significantly up-regulated in cell lines with acquired resistance to palbociclib. Supplementary Table S7. RPPA of MCF7 P, MCF7 EDR, and their PalboR derivatives.
Supplementary Figure S2 from Development and Validation of a Simplified Score to Predict Early Relapse in Newly Diagnosed Multiple Myeloma in a Pooled Dataset of 2,190 Patients
Authors: Zaccaria Gian Maria , Bertamini Luca , Petrucci Maria Teresa , Offidani Massimo , Corradini Paolo , Capra Andrea , Romano Alessandra , Liberati Anna Marina , Mannina Donato , de Fabritiis Paolo , Cascavilla Nicola , Ruggeri Marina , Mina Roberto , Patriarca Francesca , Benevolo Giulia , Belotti Angelo , Gaidano Gianluca , Nagler Arnon , Hájek Roman , Spencer Andrew , Sonneveld Pieter , Musto Pellegrino , Boccadoro Mario , Gay Francesca
Published: April 2023

Figure S2. Multivariate analysis to predict ER18 according to S-ERMM score at baseline and achievement of {greater than or equal to}VGPR at 9 months
Supplementary Materials and Methods from Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer
Authors: De Angelis Carmine , Fu Xiaoyong , Cataldo Maria Letizia , Nardone Agostina , Pereira Resel , Veeraraghavan Jamunarani , Nanda Sarmistha , Qin Lanfang , Sethunath Vidyalakshmi , Wang Tao , Hilsenbeck Susan G. , Benelli Matteo , Migliaccio Ilenia , Guarducci Cristina , Malorni Luca , Litchfield Lacey M. , Liu Jiangang , Donaldson Joshua , Selenica Pier , Brown David N. , Weigelt Britta , Reis-Filho Jorge S. , Park Ben H. , Hurvitz Sara A. , Slamon Dennis J. , Rimawi Mothaffar F. , Jansen Valerie M. , Jeselsohn Rinath , Osborne C. Kent , Schiff Rachel
Published: April 2023

Supplemental Materials and Methods and Materials present a complete description of methods, reagents, and statistics required to reproduce the experiments in the paper.
Supplementary Figure S1 from Development and Validation of a Simplified Score to Predict Early Relapse in Newly Diagnosed Multiple Myeloma in a Pooled Dataset of 2,190 Patients
Authors: Zaccaria Gian Maria , Bertamini Luca , Petrucci Maria Teresa , Offidani Massimo , Corradini Paolo , Capra Andrea , Romano Alessandra , Liberati Anna Marina , Mannina Donato , de Fabritiis Paolo , Cascavilla Nicola , Ruggeri Marina , Mina Roberto , Patriarca Francesca , Benevolo Giulia , Belotti Angelo , Gaidano Gianluca , Nagler Arnon , Hájek Roman , Spencer Andrew , Sonneveld Pieter , Musto Pellegrino , Boccadoro Mario , Gay Francesca
Published: April 2023

Figure S1. Spline function according to ER18 to dichotomize BMPCs (A) and albumin (B)
Supplementary Tables S1-S12 from Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations
Authors: Karpinets Tatiana V. , Mitani Yoshitsugu , Liu Bin , Zhang Jianhua , Pytynia Kristen B. , Sellen Linton D. , Karagiannis Danice T. , Ferrarotto Renata , Futreal Andrew P. , El-Naggar Adel K.
Published: April 2023

Table S1. Detail clinical characteristics of the cohort. Table S2. Clinicopathologic Characteristics of the Cohort Across Salivary Gland Carcinoma Subtypes. Table S3. Summary statistics of the sequenced salivary gland carcinoma subtypes. Talbe S4. Summary statistics of the whole genome sequencing for each sample. Table S5. Number of different somatic alterations found in each tumor. Table S6. Genes effected by putative somatic MEI events. Table S7. Somatic copy number variations (CNVs) in each tumors. Table S8. Incidence of somatic copy number variations of known cancer driver genes in each tumors. Table S9. Rearrangements leading to potential fusion events. Table S10. Somatic mutations identified in each tumor. Table S11. Putative germline variations associated with the salivary cancer development*. Table S12. Difference among subtypes in abundances of molecular factors used in univariate statistical models.
Supplementary Figures S1-S9 from Whole-Genome Sequencing of Common Salivary Gland Carcinomas: Subtype-Restricted and Shared Genetic Alterations
Authors: Karpinets Tatiana V. , Mitani Yoshitsugu , Liu Bin , Zhang Jianhua , Pytynia Kristen B. , Sellen Linton D. , Karagiannis Danice T. , Ferrarotto Renata , Futreal Andrew P. , El-Naggar Adel K.
Published: April 2023

Fig. S1. Difference in mean age and in mean tumor size among subtypes. Fig. S2. Genes effected by putative somatic Mobile Elements Insertions (MEI) events. Fig. S3. Rearrangements leading to potential fusion events. Fig. S4. Mutational hotspots in CIC (SLC25A1) and MUC16 genes. Fig. S5. Contribution of known somatic mutation signatures into mutational processes. Fig. S6. Genes effected by frequent germline alterations. Fig. S7. Association of patient's age (A) and each subtype (B) with survival. Fig. S8. Association of each type of structural variations (SVs) and overall survival. Fig. S9. CCDC58 mutation associated with worse survival.
Supplementary Data from Neratinib-Plus-Cetuximab in Quadruple-WT (KRAS, NRAS, BRAF, PIK3CA) Metastatic Colorectal Cancer Resistant to Cetuximab or Panitumumab: NSABP FC-7, A Phase Ib Study
Authors: Jacobs Samuel A. , Lee James J. , George Thomas J. , Wade James L. , Stella Philip J. , Wang Ding , Sama Ashwin R. , Piette Fanny , Pogue-Geile Katherine L. , Kim Rim S. , Gavin Patrick G. , Lipchik Corey , Feng Huichen , Wang Ying , Finnigan Melanie , Kiesel Brian F. , Beumer Jan H. , Wolmark Norman , Lucas Peter C. , Allegra Carmen J. , Srinivasan Ashok
Published: April 2023

Supplemental Figure Legends
Supplementary Figure S9 from Comparative Assessment of Diagnostic Homologous Recombination Deficiency–Associated Mutational Signatures in Ovarian Cancer
Authors: Sztupinszki Zsofia , Diossy Miklos , Borcsok Judit , Prosz Aurel , Cornelius Nanna , Kjeldsen Maj K. , Mirza Mansoor R. , Szallasi Zoltan
Published: April 2023

Comparison of WGS vs WES scores
Supplementary Data from Long-term Follow-up and Correlative Analysis of Two Phase II Trials of Rituximab and Lenalidomide Followed by Continuous Lenalidomide in Untreated and Relapsed/Refractory Indolent Lymphoma
Authors: Tuscano Joseph M. , Poh Christina , Kaesberg Paul , Luxardi Guilluame , Merleev Alexander , Marusina Alina , Brunson Ann , Rosenberg Aaron , Jonas Brian , Maverakis Emanual
Published: April 2023

Supplemental Table 2
Supplementary Figure S6 from Comparative Assessment of Diagnostic Homologous Recombination Deficiency–Associated Mutational Signatures in Ovarian Cancer
Authors: Sztupinszki Zsofia , Diossy Miklos , Borcsok Judit , Prosz Aurel , Cornelius Nanna , Kjeldsen Maj K. , Mirza Mansoor R. , Szallasi Zoltan
Published: April 2023

Indel signatures, TCGA WES cohort
Supplementary Data from Long-term Follow-up and Correlative Analysis of Two Phase II Trials of Rituximab and Lenalidomide Followed by Continuous Lenalidomide in Untreated and Relapsed/Refractory Indolent Lymphoma
Authors: Tuscano Joseph M. , Poh Christina , Kaesberg Paul , Luxardi Guilluame , Merleev Alexander , Marusina Alina , Brunson Ann , Rosenberg Aaron , Jonas Brian , Maverakis Emanual
Published: April 2023

Supplemental Table 3
Supplementary Figure S3 from Comparative Assessment of Diagnostic Homologous Recombination Deficiency–Associated Mutational Signatures in Ovarian Cancer
Authors: Sztupinszki Zsofia , Diossy Miklos , Borcsok Judit , Prosz Aurel , Cornelius Nanna , Kjeldsen Maj K. , Mirza Mansoor R. , Szallasi Zoltan
Published: April 2023

Indel profiles, TCGA WES cohort
Supplementary Figure S2 from Comparative Assessment of Diagnostic Homologous Recombination Deficiency–Associated Mutational Signatures in Ovarian Cancer
Authors: Sztupinszki Zsofia , Diossy Miklos , Borcsok Judit , Prosz Aurel , Cornelius Nanna , Kjeldsen Maj K. , Mirza Mansoor R. , Szallasi Zoltan
Published: April 2023

Single nucleotide mutational signatures - COSMIC, TCGA WES cohort
Supplementary Table 1 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

Clinicopathological information of five patients with diffuse-type gastric cancer.
Supplementary Figure 8 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

T cell subclusters
Supplementary Figure 6 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

Myeloid subclusters
Supplementary Table S2 from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response
Authors: Yebra Mayra , Bhargava Shruti , Kumar Avi , Burgoyne Adam M. , Tang Chih-Min , Yoon Hyunho , Banerjee Sudeep , Aguilera Joseph , Cordes Thekla , Sheth Vipul , Noh Sangkyu , Ustoy Rowan , Li Sam , Advani Sunil J. , Corless Christopher L. , Heinrich Michael C. , Kurzrock Razelle , Lippman Scott M. , Fanta Paul T. , Harismendy Olivier , Metallo Christian , Sicklick Jason K.
Published: April 2023

Supplementary Table S2. Quantitative RT-PCR primer sequences.
Supplementary Figure 4 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

Fibroblast subclusters
Supplementary Figure S5 from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response
Authors: Yebra Mayra , Bhargava Shruti , Kumar Avi , Burgoyne Adam M. , Tang Chih-Min , Yoon Hyunho , Banerjee Sudeep , Aguilera Joseph , Cordes Thekla , Sheth Vipul , Noh Sangkyu , Ustoy Rowan , Li Sam , Advani Sunil J. , Corless Christopher L. , Heinrich Michael C. , Kurzrock Razelle , Lippman Scott M. , Fanta Paul T. , Harismendy Olivier , Metallo Christian , Sicklick Jason K.
Published: April 2023

Fig. S5. Intraoperative photos of resected GIST Intraoperative photos of (A) in situ disease and (B) resected colon with omentum showing the very high-volume metastatic disease of Patient 4 (corresponding PET images in Fig. 5C-D).
Supplementary Figure 3 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

Endothelial subclusters
Supplementary Figure 2 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

Major cell lineages in the single-cell atlas
Supplementary Figure S3 from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response
Authors: Yebra Mayra , Bhargava Shruti , Kumar Avi , Burgoyne Adam M. , Tang Chih-Min , Yoon Hyunho , Banerjee Sudeep , Aguilera Joseph , Cordes Thekla , Sheth Vipul , Noh Sangkyu , Ustoy Rowan , Li Sam , Advani Sunil J. , Corless Christopher L. , Heinrich Michael C. , Kurzrock Razelle , Lippman Scott M. , Fanta Paul T. , Harismendy Olivier , Metallo Christian , Sicklick Jason K.
Published: April 2023

Fig. S3. Recapitulation of transcriptional characteristics of parental tumors and SDH-deficiency by patient-derived mSDH GIST models. A. Scatter Plot of the first two principal components and associated percentage of variance they explain for each SDH-deficient tumor and cell culture, as well as GIST882. B. The normalized gene set activity score (y-axis) for each investigated signature in Figure 3B and 3H, is displayed for each SDH-deficient tumor and cell culture, as well as GIST882. C. mSDH GIST spheroids express higher levels of 5-mC than 5-hmC when compared to GIST882 cells stained with an antibody to 5-mC (red) or to 5-hmC (green) followed by imaging with confocal fluorescence microscopy. Nuclei were stained with DAPI (blue). Scale bar, 50 ï�­m.
Supplementary Figure 10 from Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers
Authors: Jeong Hye Young , Ham In-Hye , Lee Sung Hak , Ryu Daeun , Son Sang-Yong , Han Sang-Uk , Kim Tae-Min , Hur Hoon
Published: April 2023

B cell subclusters
Supplementary Data from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response
Authors: Yebra Mayra , Bhargava Shruti , Kumar Avi , Burgoyne Adam M. , Tang Chih-Min , Yoon Hyunho , Banerjee Sudeep , Aguilera Joseph , Cordes Thekla , Sheth Vipul , Noh Sangkyu , Ustoy Rowan , Li Sam , Advani Sunil J. , Corless Christopher L. , Heinrich Michael C. , Kurzrock Razelle , Lippman Scott M. , Fanta Paul T. , Harismendy Olivier , Metallo Christian , Sicklick Jason K.
Published: April 2023

Contains supplementary figure legends
Supplementary Figure from Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models
Authors: Campian Jian L. , Ghosh Subhajit , Kapoor Vaishali , Yan Ran , Thotala Sukrutha , Jash Arijita , Hu Tong , Mahadevan Anita , Rifai Kasem , Page Logan , Lee Byung Ha , Ferrando-Martinez Sara , Wolfarth Alexandra A. , Yang Se Hwan , Hallahan Dennis , Chheda Milan G. , Thotala Dinesh
Published: April 2023

Supplementary Figure from Long-Acting Recombinant Human Interleukin-7, NT-I7, Increases Cytotoxic CD8 T Cells and Enhances Survival in Mouse Glioma Models
Supplementary Figure Legends from Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma
Authors: Waldschmidt Johannes M. , Kloeber Jake A. , Anand Praveen , Frede Julia , Kokkalis Antonis , Dimitrova Valeriya , Potdar Sayalee , Nair Monica S. , Vijaykumar Tushara , Im Nam Gyu , Guillaumet-Adkins Amy , Chopra Nitish , Stuart Hannah , Budano Lillian , Sotudeh Noori , Guo Guangwu , Grassberger Clemens , Yee Andrew J. , Laubach Jacob P. , Richardson Paul G. , Anderson Kenneth C. , Raje Noopur S. , Knoechel Birgit , Lohr Jens G.
Published: April 2023

Figure Legends S1-S15
Figure S8 from Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma
Authors: Waldschmidt Johannes M. , Kloeber Jake A. , Anand Praveen , Frede Julia , Kokkalis Antonis , Dimitrova Valeriya , Potdar Sayalee , Nair Monica S. , Vijaykumar Tushara , Im Nam Gyu , Guillaumet-Adkins Amy , Chopra Nitish , Stuart Hannah , Budano Lillian , Sotudeh Noori , Guo Guangwu , Grassberger Clemens , Yee Andrew J. , Laubach Jacob P. , Richardson Paul G. , Anderson Kenneth C. , Raje Noopur S. , Knoechel Birgit , Lohr Jens G.
Published: April 2023

Copy number variations in dabrafenib-persistent U266 single-cell clones as compared to baseline
Figure S2 from Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma
Authors: Waldschmidt Johannes M. , Kloeber Jake A. , Anand Praveen , Frede Julia , Kokkalis Antonis , Dimitrova Valeriya , Potdar Sayalee , Nair Monica S. , Vijaykumar Tushara , Im Nam Gyu , Guillaumet-Adkins Amy , Chopra Nitish , Stuart Hannah , Budano Lillian , Sotudeh Noori , Guo Guangwu , Grassberger Clemens , Yee Andrew J. , Laubach Jacob P. , Richardson Paul G. , Anderson Kenneth C. , Raje Noopur S. , Knoechel Birgit , Lohr Jens G.
Published: April 2023

Quality parameters of scRNA-seq data after filtering
Figure S15 from Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma
Authors: Waldschmidt Johannes M. , Kloeber Jake A. , Anand Praveen , Frede Julia , Kokkalis Antonis , Dimitrova Valeriya , Potdar Sayalee , Nair Monica S. , Vijaykumar Tushara , Im Nam Gyu , Guillaumet-Adkins Amy , Chopra Nitish , Stuart Hannah , Budano Lillian , Sotudeh Noori , Guo Guangwu , Grassberger Clemens , Yee Andrew J. , Laubach Jacob P. , Richardson Paul G. , Anderson Kenneth C. , Raje Noopur S. , Knoechel Birgit , Lohr Jens G.
Published: April 2023

IACS-010759 sensitivity in dabrafenib-persistent vs. naïve single-cell clones
Figure S13 from Single-Cell Profiling Reveals Metabolic Reprogramming as a Resistance Mechanism in BRAF-Mutated Multiple Myeloma
Authors: Waldschmidt Johannes M. , Kloeber Jake A. , Anand Praveen , Frede Julia , Kokkalis Antonis , Dimitrova Valeriya , Potdar Sayalee , Nair Monica S. , Vijaykumar Tushara , Im Nam Gyu , Guillaumet-Adkins Amy , Chopra Nitish , Stuart Hannah , Budano Lillian , Sotudeh Noori , Guo Guangwu , Grassberger Clemens , Yee Andrew J. , Laubach Jacob P. , Richardson Paul G. , Anderson Kenneth C. , Raje Noopur S. , Knoechel Birgit , Lohr Jens G.
Published: April 2023

Metabolic flux analysis in U266 and DP6 single-cell clones
Supplementary Table S3 from Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors
Authors: Hollebecque Antoine , Chung Hyun C. , de Miguel Maria J. , Italiano Antoine , Machiels Jean-Pascal , Lin Chia-Chi , Dhani Neesha C. , Peeters Marc , Moreno Victor , Su Wu-Chou , Chow Kay Hoong , Galvao Violeta R. , Carlsen Michelle , Yu Danni , Szpurka Anna M. , Zhao Yumin , Schmidt Shelly L. , Gandhi Leena , Xu Xiaojian , Bang Yung-Jue
Published: April 2023

Table S3. Baseline distribution of tumor microenvironment biomarkers in MSI-H/dMMR patients
Supplementary Figure S4 from Safety and Antitumor Activity of α-PD-L1 Antibody as Monotherapy or in Combination with α-TIM-3 Antibody in Patients with Microsatellite Instability–High/Mismatch Repair–Deficient Tumors
Authors: Hollebecque Antoine , Chung Hyun C. , de Miguel Maria J. , Italiano Antoine , Machiels Jean-Pascal , Lin Chia-Chi , Dhani Neesha C. , Peeters Marc , Moreno Victor , Su Wu-Chou , Chow Kay Hoong , Galvao Violeta R. , Carlsen Michelle , Yu Danni , Szpurka Anna M. , Zhao Yumin , Schmidt Shelly L. , Gandhi Leena , Xu Xiaojian , Bang Yung-Jue
Published: April 2023

Figure S4. Changes in intratumoral immune markers after treatment
Supplementary Fig S3 from Transcriptomic Profiling Identifies a Risk Stratification Signature for Predicting Peritoneal Recurrence and Micrometastasis in Gastric Cancer
Authors: Lee In-Seob , Lee Heonyi , Hur Hoon , Kanda Mitsuro , Yook Jeong-Hwan , Kim Byung-Sik , Woo Yanghee , Kodera Yasuhiro , Kim Kwangsoo , Goel Ajay
Published: April 2023

Schematic illustrating the potential benefit of risk stratification with primary gastric cancer tissue-derived biomarker.
Supplementary Fig S2 from Transcriptomic Profiling Identifies a Risk Stratification Signature for Predicting Peritoneal Recurrence and Micrometastasis in Gastric Cancer
Authors: Lee In-Seob , Lee Heonyi , Hur Hoon , Kanda Mitsuro , Yook Jeong-Hwan , Kim Byung-Sik , Woo Yanghee , Kodera Yasuhiro , Kim Kwangsoo , Goel Ajay
Published: April 2023

Violin plots of two important genes, ZBTB1 and CAVIN2, exhibiting differences in expression level between tumors with and without peritoneal recurrence in (A) the training cohort and (B) the validation cohort.
Figure S4 from Unbiased Detection of Driver Mutations in Extramammary Paget Disease
Authors: Ishida Yoshihiro , Kakiuchi Nobuyuki , Yoshida Kenichi , Inoue Yoshikage , Irie Hiroyuki , Kataoka Tatsuki R. , Hirata Masahiro , Funakoshi Takeru , Matsushita Shigeto , Hata Hiroo , Uchi Hiroshi , Yamamoto Yuki , Fujisawa Yasuhiro , Fujimura Taku , Saiki Ryunosuke , Takeuchi Kengo , Shiraishi Yuichi , Chiba Kenichi , Tanaka Hiroko , Otsuka Atsushi , Miyano Satoru , Kabashima Kenji , Ogawa Seishi
Published: April 2023

Lollipop plot of NUP93 comparing EMPD and PanCancer Atlas dataset
Figure S2 from Unbiased Detection of Driver Mutations in Extramammary Paget Disease
Authors: Ishida Yoshihiro , Kakiuchi Nobuyuki , Yoshida Kenichi , Inoue Yoshikage , Irie Hiroyuki , Kataoka Tatsuki R. , Hirata Masahiro , Funakoshi Takeru , Matsushita Shigeto , Hata Hiroo , Uchi Hiroshi , Yamamoto Yuki , Fujisawa Yasuhiro , Fujimura Taku , Saiki Ryunosuke , Takeuchi Kengo , Shiraishi Yuichi , Chiba Kenichi , Tanaka Hiroko , Otsuka Atsushi , Miyano Satoru , Kabashima Kenji , Ogawa Seishi
Published: April 2023

Performance of copy number analysis pipeline for samples with low tumor contents
Figure S1 from Unbiased Detection of Driver Mutations in Extramammary Paget Disease
Authors: Ishida Yoshihiro , Kakiuchi Nobuyuki , Yoshida Kenichi , Inoue Yoshikage , Irie Hiroyuki , Kataoka Tatsuki R. , Hirata Masahiro , Funakoshi Takeru , Matsushita Shigeto , Hata Hiroo , Uchi Hiroshi , Yamamoto Yuki , Fujisawa Yasuhiro , Fujimura Taku , Saiki Ryunosuke , Takeuchi Kengo , Shiraishi Yuichi , Chiba Kenichi , Tanaka Hiroko , Otsuka Atsushi , Miyano Satoru , Kabashima Kenji , Ogawa Seishi
Published: April 2023

Validation of exome sequencing results by amplicon-based deep sequencing
Supplementary Tables ST1-ST6 from Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment
Authors: Hallett Robin M. , Bonfill-Teixidor Ester , Iurlaro Raffaella , Arias Alexandra , Raman Swetha , Bayliss Peter , Egorova Olga , Neva-Alejo Almudena , McGray AJ Robert , Lau Esther , Bosch Alexandre , Beilschmidt Melissa , Maetzel Dorothea , Fransson Johan , Huber-Ruano Isabel , Anido Judit , Julien Jean-Philippe , Giblin Patricia , Seoane Joan
Published: April 2023

Supplementary Table 1: Description of TCGA derived mRNA expression cohorts used to examine LIF expression and associated transcript signaturesSupplementary Table 2: Transcription signatures used to identify biological processes and cell types correlated with LIF expression.Supplementary Table 3: GSEA results of REACTOME pathway gene sets for enriched gene sets in LIF treated macrophages. Supplementary Table 4: Leading edge genes selected from GSEA analysis of LIF treated macrophages with REACTOME pathway gene sets Supplementary Table 5: Summary of data collection statistics for crystal structures of MSC-1:LIF co-complex Supplementary Table 6: Summary of interactions between MSC-1 and LIF
Figure S5 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study
Authors: Delaidelli Alberto , Dunham Christopher , Santi Mariarita , Negri Gian Luca , Triscott Joanna , Zheludkova Olga , Golanov Andrey , Ryzhova Marina , Okonechnikov Konstantin , Schrimpf Daniel , Stichel Damian , Ellison David W. , von Deimling Andreas , Kool Marcel , Pfister Stefan M. , Ramaswamy Vijay , Korshunov Andrey , Taylor Michael D. , Sorensen Poul H.
Published: April 2023

Fig S5. Progression free survival analysis by Kaplan Meier plotting of patients with Group 3/4 medulloblastoma (BH cohort), after stratification based on therapeutic approach and TPD52 IHC. Children in A-B were treated with chemotherapy-only protocols. Patients in C were treated with RT + chemotherapy and in D with therapy intensification. Global p value is reported in the figure. Individual p values (TPD52 neg vs TPD52 => 50%) are as follows: A p=0.0039, B p=0.0079, C p=0.012, D p=0.065.
Figure S1 from Clinically Tractable Outcome Prediction of Non-WNT/Non-SHH Medulloblastoma Based on TPD52 IHC in a Multicohort Study
Authors: Delaidelli Alberto , Dunham Christopher , Santi Mariarita , Negri Gian Luca , Triscott Joanna , Zheludkova Olga , Golanov Andrey , Ryzhova Marina , Okonechnikov Konstantin , Schrimpf Daniel , Stichel Damian , Ellison David W. , von Deimling Andreas , Kool Marcel , Pfister Stefan M. , Ramaswamy Vijay , Korshunov Andrey , Taylor Michael D. , Sorensen Poul H.
Published: April 2023

Fig S1. Survival analysis of Group 3 medulloblastoma, with groups separation based on FKBP5 (A), MAK16 (B), RRP15 (C) and PALMD (D) median mRNA expression in previously published cohorts(8). E) Density plot representing protein half-lives in mouse brain (26). Grey line represents the mean protein half-life.
Supplementary Data from Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma
Authors: Hannan Raquibul , Mohamad Osama , Diaz de Leon Alberto , Manna Subrata , Pop Laurentiu M. , Zhang Ze , Mannala Samantha , Christie Alana , Christley Scott , Monson Nancy , Ishihara Dan , Hsu Eric J. , Ahn Chul , Kapur Payal , Chen Mingyi , Arriaga Yull , Courtney Kevin , Cantarel Brandi , Wakeland Edward K. , Fu Yang-Xin , Pedrosa Ivan , Cowell Lindsay , Wang Tao , Margulis Vitaly , Choy Hak , Timmerman Robert D. , Brugarolas James
Published: April 2023

Multiple tables
Supplementary Data from Treatment-free Survival after Immune Checkpoint Inhibitor Therapy versus Targeted Therapy for Advanced Renal Cell Carcinoma: 42-Month Results of the CheckMate 214 Trial
Authors: Regan Meredith M. , Jegede Opeyemi A. , Mantia Charlene M. , Powles Thomas , Werner Lillian , Motzer Robert J. , Tannir Nizar M. , Lee Chung-Han , Tomita Yoshihiko , Voss Martin H. , Plimack Elizabeth R. , Choueiri Toni K. , Rini Brian I. , Hammers Hans J. , Escudier Bernard , Albiges Laurence , Huo Stephen , Del Tejo Viviana , Stwalley Brian , Atkins Michael B. , McDermott David F.
Published: April 2023

Supplementary Data from Treatment-free Survival after Immune Checkpoint Inhibitor Therapy versus Targeted Therapy for Advanced Renal Cell Carcinoma: 42-Month Results of the CheckMate 214 Trial
Supplemental Table 3 from Phase II Study of Pembrolizumab in Combination with Doxorubicin in Metastatic and Unresectable Soft-Tissue Sarcoma
Authors: Livingston Michael B. , Jagosky Megan H. , Robinson Myra M. , Ahrens William A. , Benbow Jennifer H. , Farhangfar Carol J. , Foureau David M. , Maxwell Deirdre M. , Baldrige Emily A. , Begic Xhevahire , Symanowski James T. , Steuerwald Nury M. , Anderson Colin J. , Patt Joshua C. , Kneisl Jeffrey S. , Kim Edward S.
Published: April 2023

Treatment Emergent Adverse Events Attributed to Either Doxorubicin, Pembrolizumab, or Both, Any Grade
Supplemental Table 2 from Phase II Study of Pembrolizumab in Combination with Doxorubicin in Metastatic and Unresectable Soft-Tissue Sarcoma
Authors: Livingston Michael B. , Jagosky Megan H. , Robinson Myra M. , Ahrens William A. , Benbow Jennifer H. , Farhangfar Carol J. , Foureau David M. , Maxwell Deirdre M. , Baldrige Emily A. , Begic Xhevahire , Symanowski James T. , Steuerwald Nury M. , Anderson Colin J. , Patt Joshua C. , Kneisl Jeffrey S. , Kim Edward S.
Published: April 2023

All Treatment Emergent Adverse Events Regardless of Causality, Any Grade
Supplementary Table from Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor
Authors: Wichmann Jürgen , Rynn Caroline , Friess Thomas , Petrig-Schaffland Jeannine , Kornacker Martin , Handl Cornelia , Emmenegger Jasmin , Eckmann Jan , Herting Frank , Frances Nicolas , Hunziker Daniel , Krummenacher Daniela , Rüttinger Dominik , Ribeiro Alison , Bacac Marina , Brigo Alessandro , Hewings David S. , Dummer Reinhard , Levesque Mitchell P. , Schnetzler Gabriel , Martoglio Bruno , Bischoff James R. , Pettazzoni Piergiorgio
Published: April 2023

Supplementary Table from Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor
Supplementary Table from Tumor Immune Microenvironment Changes by Multiplex Immunofluorescence Staining in a Pilot Study of Neoadjuvant Talazoparib for Early-Stage Breast Cancer Patients with a Hereditary BRCA Mutation
Authors: Kumar Tapsi , Hobbs Evie , Yang Fei , Chang Jeffrey T. , Contreras Alejandro , Cuentas Edwin Roger Parra , Garber Haven , Lee Sanghoon , Lu Yiling , Scoggins Marion E. , Adrada Beatriz E. , Whitman Gary J. , Arun Banu K. , Mittendorf Elizabeth A. , Litton Jennifer K.
Published: April 2023

Supplementary Table from Tumor Immune Microenvironment Changes by Multiplex Immunofluorescence Staining in a Pilot Study of Neoadjuvant Talazoparib for Early-Stage Breast Cancer Patients with a Hereditary BRCA Mutation
Supplementary Materials and Methods from Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma
Authors: Gao Yajing , Päivinen Pekka , Tripathi Sushil , Domènech-Moreno Eva , Wong Iris P.L. , Vaahtomeri Kari , Nagaraj Ashwini S. , Talwelkar Sarang S. , Foretz Marc , Verschuren Emmy W. , Viollet Benoit , Yan Yan , Mäkelä Tomi P.
Published: April 2023

Supplementary Materials and Methods
Supplementary Data from Single‐Cell Immune Mapping of Melanoma Sentinel Lymph Nodes Reveals an Actionable Immunotolerant Microenvironment
Authors: Yaddanapudi Kavitha , Stamp Bryce F. , Subrahmanyam Priyanka B. , Smolenkov Andrei , Waigel Sabine J. , Gosain Rahul , Egger Michael E. , Martin Robert C.G. , Buscaglia Robert , Maecker Holden T. , McMasters Kelly M. , Chesney Jason A.
Published: April 2023

Supplementary Data from Single‐Cell Immune Mapping of Melanoma Sentinel Lymph Nodes Reveals an Actionable Immunotolerant Microenvironment
Supplemental Figure 3 from Safety, Efficacy, and Biomarker Analysis of Toripalimab in Patients with Previously Treated Advanced Urothelial Carcinoma: Results from a Multicenter Phase II Trial POLARIS-03
Authors: Sheng Xinan , Chen Haige , Hu Bin , Yao Xudong , Liu Ziling , Yao Xin , Guo Hongqian , Hu Yi , Ji Zhigang , Luo Hong , Shi Benkang , Liu Jiyan , Wu Jin , Zhou FangJian , He Zhisong , Fan Jinhai , Wang Weifeng , Feng Hui , Yao Sheng , Keegan Patricia , Huang Yiran , Guo Jun
Published: April 2023

The mutational signature characterized by exposure to aristolochic acid.
Supplementary Data from NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
Authors: Otani Yoshihiro , Yoo Ji Young , Lewis Cole T. , Chao Samantha , Swanner Jessica , Shimizu Toshihiko , Kang Jin Muk , Murphy Sara A. , Rivera-Caraballo Kimberly , Hong Bangxing , Glorioso Joseph C. , Nakashima Hiroshi , Lawler Sean E. , Banasavadi-Siddegowda Yeshavanth , Heiss John D. , Yan Yuanqing , Pei Guangsheng , Caligiuri Michael A. , Zhao Zhongming , Chiocca E. Antonio , Yu Jianhua , Kaur Balveen
Published: April 2023

Supplementary Data from NOTCH-Induced MDSC Recruitment after oHSV Virotherapy in CNS Cancer Models Modulates Antitumor Immunotherapy
Supplementary Legend from Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma
Authors: Chahoud Jad , Gleber-Netto Frederico O. , McCormick Barrett Z. , Rao Priya , Lu Xin , Guo Ming , Morgan Maggaret B. , Chu Randy A. , Martinez-Ferrer Magaly , Eterovic Agda Karina , Pickering Curtis R. , Pettaway Curtis A.
Published: April 2023

Supplementary Legend
Supplementary Figure S2 from Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma
Authors: Chahoud Jad , Gleber-Netto Frederico O. , McCormick Barrett Z. , Rao Priya , Lu Xin , Guo Ming , Morgan Maggaret B. , Chu Randy A. , Martinez-Ferrer Magaly , Eterovic Agda Karina , Pickering Curtis R. , Pettaway Curtis A.
Published: April 2023

Figure S2 - PSCC driver genes estimated by mutation positional analysis as described by Tamborero et al. (2013). PIK3CA gain of function mutations were detected in 20.6% of PSCC patients and were enriched in known hotspots in the C2 (E453K, n=1) and in the helical domains (E545K/G, n=4 and E542K, n=2). CDKN2A mutations affected 29.4% of PSCC patients, involving the major known mutation hotspots W110* (n=3, likely pathogenic), R80* (n=2, pathogenic), R58* (n=1, pathogenic), R88* (n=1, pathogenic). The other CDKN2A mutations observed were less common, such as the G65fs (n=1), D108G (n=1) and R115fs (n=1) of uncertain significance.
Supplementary Tables S2-S5 from Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer
Authors: Topka Sabine , Steinsnyder Zoe , Ravichandran Vignesh , Tkachuk Kaitlyn , Kemel Yelena , Bandlamudi Chaitanya , Winkel Madsen Mogens , Furberg Helena , Ouerfelli Ouathek , Rudin Charles M. , Iyer Gopa , Lipkin Steven M. , Mukherjee Semanti , Solit David B. , Berger Michael F. , Bajorin Dean F. , Rosenberg Jonathan E. , Taylor Barry S. , de Stanchina Elisa , Vijai Joseph , Offit Kenneth
Published: April 2023

Supplementary Tables S2-S5
Supplementary Data from Targeting Germline- and Tumor-Associated Nucleotide Excision Repair Defects in Cancer
Authors: Topka Sabine , Steinsnyder Zoe , Ravichandran Vignesh , Tkachuk Kaitlyn , Kemel Yelena , Bandlamudi Chaitanya , Winkel Madsen Mogens , Furberg Helena , Ouerfelli Ouathek , Rudin Charles M. , Iyer Gopa , Lipkin Steven M. , Mukherjee Semanti , Solit David B. , Berger Michael F. , Bajorin Dean F. , Rosenberg Jonathan E. , Taylor Barry S. , de Stanchina Elisa , Vijai Joseph , Offit Kenneth
Published: April 2023

Supplementary Methods, Supplementary Figures S1-S11, Supplementary Tables S1, S6, S8-11
Supplementary Data from High Detection Rates of Pancreatic Cancer Across Stages by Plasma Assay of Novel Methylated DNA Markers and CA19-9
Authors: Majumder Shounak , Taylor William R. , Foote Patrick H. , Berger Calise K. , Wu Chung Wah , Mahoney Douglas W. , Bamlet William R. , Burger Kelli N. , Postier Neil , de la Fuente Jaime , Doering Karen A. , Lidgard Graham P. , Allawi Hatim T. , Petersen Gloria M. , Chari Suresh T. , Ahlquist David A. , Kisiel John B.
Published: April 2023

Supplementary Tables and Figure Legends
Supplementary Data from Combined Analysis of Concordance between Liquid and Tumor Tissue Biopsies for RAS Mutations in Colorectal Cancer with a Single Metastasis Site: The METABEAM Study
Authors: Kagawa Yoshinori , Elez Elena , García-Foncillas Jesús , Bando Hideaki , Taniguchi Hiroya , Vivancos Ana , Akagi Kiwamu , García Ariadna , Denda Tadamichi , Ros Javier , Nishina Tomohiro , Baraibar Iosune , Komatsu Yoshito , Ciardiello Davide , Oki Eiji , Kudo Toshihiro , Kato Takeshi , Yamanaka Takeharu , Tabernero Josep , Yoshino Takayuki
Published: April 2023

Supplementary Figures S1-S4 and Supplementary Tables S1-S4
Supplementary Data Table S2 from Follicular Lymphoma–associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation
Authors: Hu Nan , Wang Fangyang , Sun Tianyu , Xu Zhengfan , Zhang Jing , Bernard Denzil , Xu Shilin , Wang Shaomeng , Kaminski Mark , Devata Suma , Phillips Tycel , Malek Sami N.
Published: April 2023

Results from IP-mass spec of HA-BTK WT and two HA-BTK mutants and a control (BTK-/- reconstituted with empty vector FG9) and embedded VENN diagram
Supplementary Table S6 from A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2–Induced Glycolytic Reprogramming in Glioblastoma
Authors: Beinat Corinne , Patel Chirag B. , Haywood Tom , Murty Surya , Naya Lewis , Castillo Jessa B. , Reyes Samantha T. , Phillips Megan , Buccino Pablo , Shen Bin , Park Jun Hyung , Koran Mary Ellen I. , Alam Israt S. , James Michelle L. , Holley Dawn , Halbert Kim , Gandhi Harsh , He Joy Q. , Granucci Monica , Johnson Eli , Liu Daniel Dan , Uchida Nobuko , Sinha Rahul , Chu Pauline , Born Donald E. , Warnock Geoffrey I. , Weissman Irving , Hayden-Gephart Melanie , Khalighi Mehdi , Massoud Tarik F. , Iagaru Andrei , Davidzon Guido , Thomas Reena , Nagpal Seema , Recht Lawrence D. , Gambhir Sanjiv Sam
Published: April 2023

Blood chemistry laboratory testing results of the patients imaged with [18F]DASA-23
Supplementary Table S1 from A Clinical PET Imaging Tracer ([18F]DASA-23) to Monitor Pyruvate Kinase M2–Induced Glycolytic Reprogramming in Glioblastoma
Authors: Beinat Corinne , Patel Chirag B. , Haywood Tom , Murty Surya , Naya Lewis , Castillo Jessa B. , Reyes Samantha T. , Phillips Megan , Buccino Pablo , Shen Bin , Park Jun Hyung , Koran Mary Ellen I. , Alam Israt S. , James Michelle L. , Holley Dawn , Halbert Kim , Gandhi Harsh , He Joy Q. , Granucci Monica , Johnson Eli , Liu Daniel Dan , Uchida Nobuko , Sinha Rahul , Chu Pauline , Born Donald E. , Warnock Geoffrey I. , Weissman Irving , Hayden-Gephart Melanie , Khalighi Mehdi , Massoud Tarik F. , Iagaru Andrei , Davidzon Guido , Thomas Reena , Nagpal Seema , Recht Lawrence D. , Gambhir Sanjiv Sam
Published: April 2023

[18F]DASA-23 administered activity in healthy volunteers