bluuebunny/crossref_metadata_2025 huggingface dataset:
Ecological Supply Chain: Tools For Evaluating E-Waste – World Perspective
Authors: Meihui Liao , Khokhar Maryam , Patra Indrajit
Published: July 2023

When a company's supply chain has achieved a desirable degree of eco-friendliness in all regards, from a sustainability perspective, its performance will be satisfactory. Since the closed-loop e-waste supply chain's operations are primarily focused on achieving sustainability objectives related to the manufacturing, distribution, reusing, and discarding electrical components, it is crucial to evaluate its success in this area. In order to monitor the performance of supply chains and enhance the processes, the supply chain operations reference model offers suggestions and benchmarking tools. In this study, a conceptual framework is illustrated to show how these standards could be used in the E-waste supply chain to link business processes, metrics, industry standards, and technology in order to enhance the relationship and coordination between the supply chain members and to increase sustainability throughout the supply chain. Insufficient attention so far has been paid to the SCOR model's sustainability criteria, according to an assessment of the literature. Consequently, in the wake of portraying the structure of Supply Chain Operation Reference model, we make sense of which credits should be included in Supply Chain Operation Reference so to reflect manageability and which cycles and practices are related with every standard or should be remembered for Supply Chain Operation Reference to lay out the connection between execution, cycles, and practices.
A Study on the Impact of Reform and Opening-up on Sustainable Development: Evidence from China
Authors: Xiang Linglin , Zhang Huaixi , Lyu Yiqing
Published: July 2023

This paper selected the data of 284 prefectural-level cities in China in the time range of 2011 to 2020 as the research sample, and established an index system of sustainable development consisting of 22 indicators including economic development, social progress, ecological environment and public institutions and so on, to comprehensive evaluate the sustainability of the cities. Total annual investment in pollution control is selected as the proxy variable of reform, and annual actual amount of foreign investment used is selected as the proxy variable of opening-up, to empirically explore the impact of the two on sustainable development. The results of empirical analysis show that reform and opening-up has a significant positive impact on sustainable development. After fixing time and individual effect, it is found that the effect of reform is more prominent. Regional heterogeneity analysis shows that, the impact strength of reform and opening-up in the east is larger than that in the middle and west of China. To study the spatial auto-correlation and spillover effect, Moran’s I was calculated and spatial Durbin model was constructed based on the weight matrix of geographical distance, which produced the results that spatial agglomeration is evident for sustainability, and that reform has a significant positive spillover effect. Further, considering the time auto-correlation of sustainability, a dynamic panel model is established, and dynamic threshold regression is carried out. Results show that lag effect of sustainability is significant, and a certain threshold must reform reach can sustainable development be promoted. This paper puts forward several policy suggestions in terms of formulating effective sustainable development strategy, to provide insights for new-pattern urbanization in the future.
Supervised Credit, Government Strategies and Green Development: Evidence from China
Authors: Zhang Bingbing
Published: July 2023

This study examines the relationship between supervised credit (SC), government strategies, and green development (GD) utilizing the instrumental variable two-stage least squares (IV-2SLS) and spatial econometric model and panel data from 30 provinces and cities in China from 2006 to 2020. The study reached the following main results. First, untrustworthy punishment and trustworthy incentives promote the environmental protection through optimal allocation of supervised resources, which can be positively regulated by the government transformation. Second, beggar-thy-neighbor and free rider can be found in government environmental SC. Strengthening punishment in neighboring regions will have a negative effect on the local GD, whereas increasing incentives will have the opposite effect. Third, strategic interactions among various governmental sections have varying effects on GD. The eastern regions implement difference-based promotion for trustworthy incentives and ineffective imitation for untrustworthy punishment. The central and western regions, on the other hand, use ineffective imitation for trustworthy incentives and inhibiting imitation for untrustworthy punishment, the eastern regions implement ineffective imitation and the central and western regions execute inhibiting imitation. Finally, when R&D investment exceeds a certain threshold, but the industrial structure is lower, the untrustworthy punishment can play its promoting role; otherwise, the trustworthy incentives will turn over. The study findings reveal the unique mechanism of SC and provides new impetus regional policymakers to promote sustainable GD.
Environment, Economy and Society – the Body, Mind and Soul of Sustainable Design of Buildings
Authors: Venkatesh G
Published: July 2023

The design process in general, and the one for buildings in particular has evolved and become increasingly intricate, with additional layers and factors becoming relevant, as the drive towards sustainability (the Sustainable development goals defined by the United Nations in 2015) has gathered steam. This short chapter focuses on the diversity of issues which sustainable building design is likely to be influenced by, in the years ahead.
Artificial Intelligence and Environmental Protection of Buildings
Authors: Chen Zheng , He Yu
Published: July 2023

Global environmental pollution has an extremely negative impact on the population of the planet and threatens the future of mankind. One of the main sources of waste and toxic emissions into the atmosphere is the construction sector. It is necessary to find ways to minimize the damage caused to nature. Currently, artificial intelligence technologies are among the most promising ways to improve the environment. Automatic control systems solve a number of problems related to reducing costs and resources, full use of renewable energy sources, improving the safety of energy systems, and many others. The purpose of this article is to determine the functionality of artificial intelligence technologies and ways of their application in green construction. To solve this problem, methods of analysis and synthesis of existing information models were applied. The article discloses automatic control systems in the design, construction, and operation of buildings. These include well-known methods, such as Building Information Model, Machine Learning, Deep Learning, and narrow-profile ones: Response Surface Methodology, Multi-Agent System, Digital Twins, etc. In addition, the study states that when planning and arranging green buildings must adhere to the following principles: high energy efficiency, rational use of natural resources, adaptation to the environment and climate, ensuring comfort and safety for residents. The article presents the standards of green construction existing in the world. This work can serve as a guide when choosing information models and is of practical value in the development of green buildings.
Reconstruction of the Urban Historical Centre: Contemporary Problems, Difficulties, and Perspectives
Authors: Goussous Jawdat , Hmood Kabila Faris
Published: July 2023

Adapting historical city buildings into modern facilities is a basic problem in architecture today. In many large cities, historical centers preserve cultural heritage, including spiritual, cultural, economic, and social capital of irreplaceable value. Because of their importance, these centers must consider the unique characteristics of their surroundings, including harmony of size, spatial composition, architectural environment, facades, and the facilities in general. Disharmony in the architectural design of these centers is evident in the non-compliance of new objects, particularly in historical areas of the city. The restoration, reconstruction, and repair of these historical sites require special knowledge. Experts with this special knowledge can implement modern methods, strategic and operational modes of architecture, and public programs to preserve the historical and cultural values of these sites, thus preserving them for the future, which follows the sustainable development concept. The main conclusion of the research is that unique modern buildings, including novel architectural and constructive elements, can coexist with historical ones by using right policies and methods.
Role of Endoscopic Procedure in Foreign Body (Button Battery) Ingestion in Children: A Case Report
Authors: Lampus Harsali , Candy Candy , Rendy Leo , Rangan Andy A.
Published: July 2023

Abstract: Foreign body (FB) ingestion is a common problem especially in children below the age of 5 years. Due to the extensive use of batteries as power supply in electronic gadgets, cases of button battery ingestion have become more common. If a button battery was found in the stomach of a child under the age of five, it should be assessed for esophageal injury and removed endoscopically, if at all possible, within 24 to 48 hours. We reported a 3-year-old boy who swallowed a foreign body three hours before being admitted to the hospital. Initially the patient was playing with robot toys that used batteries, then a battery of the robots was accidently swallowed. The patient had no symptoms and physical examinations showed no abnormalities. Abdominal X-ray examination revealed a foreign body located in the stomach. The patient underwent endoscopic foreign body removal but no foreign body was found until the second part of duodenum. Therefore, an exploratory laparotomy was performed, and the foreign body, a button battery, was removed from the ileum. In conclusion, since endoscopic foreign body removal failed to remove the foreign body in this patient, an exploratory laparotomy was performed and through antimesenterial ileotomy, the foreign body, a button battery, was successfully removed.
Keywords: foreign body; endoscopic foreign body removal; exploratory laparotomy
EVALUASI SISTEM PROSEDUR UANG PERSEDIAAN, GANTI UANG DAN MEKANISME PEMBAYARAN LANGSUNG PADA KANTOR PELAYANAN PERBENDAHARAAN NEGARA BITUNG
Authors: Fauziah Ayun , Manossoh Hendrik , Kindangen Wulan D.
Published: July 2023

Didalam pencairan dana UP, GU dan LS  terdapat sebuah sistem prosedur yang harus dilakukan sesuai dengan alur yang sudah ditetapkan dan harus berurutan sesuai dengan prosedur yang telah dibuat, agar nantinya satuan kerja tidak menerima konsekuensi yang bisa menghambat dalam pelaksanaan rencana anggaran tahun berjalan yang sudah dibuat, seperti pemotongan UP atau penolakan SP2D. Tujuan Penelitian Ini Untuk Mengevaluasi Pelaksanaan Sistem Prosedur Uang Persediaan, Ganti Uang dan Mekanisme Pembayaran Langsung Berdasarkan PMK NO.210/PMK.05/2022 pada Kantor Pelayanan Perbendaharaan Negara Bitung apakah sudah sesuai. Jenis penelitian yang digunakan yaitu deskriptif kualitatif. Berdasarkan hasil penelitian yang dilakukan menunjukan bahwa sistem prosedur Uang Persediaan, Ganti Uang, Dan Mekanisme Pembayaran Langsung pada Kantor Pelayanan Perbendaharaan Negara Bitung khususnya prosedur pengajuan SPP, SPM dan SP2D sudah sesuai dengan Peraturan Menteri Keuangan (PMK) Nomor 210 tahun 2022 tentang Tata Cara Pembayaran Dalam Rangka Pelaksanaan Anggaran Pendapatan Dan Belanja Negara, namun masih terdapat sistem pengendalian internal (SPI) yang belum berjalan dengan optimal pada Kantor Pelayanan Perbendaharaan Negara Bitung dan masih membutuhkan perbaikan.
 
Kata Kunci: evaluasi, uang persediaan, ganti uang, pembayaran langsung, PMK No. 210 Tahun 2022
Evaluasi Penerapan Akuntansi Belanja Pada Dinas Kebudayaan dan Pariwisata Kabupaten Minahasa
Authors: Sumual Shella Reza , Tinangon Jantje , Wokas Heince R. N.
Published: July 2023

Setiap negara memiliki penerapan standar akuntansi pemerintahan yang berbeda-beda. Di Indonesia Penerapan Standar Akuntansi Pemerintahan diatur dalam Permendagri Nomor 64 Tahun 2013 tentang Penerapan Standar Akuntansi Pemerintahan Berbasis Akrual Pada Pemerintah Daerah. Belanja menurut Permendagri Nomor 64 tahun 2013 adalah semua pengeluaran dari Rekening Kas Umum Daerah yang mengurangi Saldo Anggaran Lebih dalam periode tahun anggaran bersangkutan yang tidak akan diperoleh pembayarannya kembali oleh pemerintah daerah. Dinas Kebudayaan dan Pariwisata Minahasa adalah salah satu Satuan Kerja Perangkat Daerah (SKPD) yang berada di wilayah Kabupaten Minahasa. Dalam pelaksanaan kegiatan pemerintahannya diharuskan untuk menyusun laporan keuangan pemerintah berdasarkan Standar Akuntansi Pemerintahan yang berlaku. Tujuan penelitian ini adalah untuk mengetahui penerapan akuntansi belanja pada Dinas Kebudayaaan dan Pariwisata Kabupaten Minahasa berdasarkan Permendagri Nomor 64 Tahun 2013. Hasil Penelitian menunjukan bahwa Penerapan Akuntansi Belanja di Dinas Kebudayaan Dan Pariwisata Kabupaten Minahasa sudah sesuai dengan aturan Permendagri Nomor 64 tahun 2013.
Kata Kunci: Penerapan Standar Akuntansi Pemerintah, Belanja Daerah, SKPD
ANALISIS SISTEM DAN PROSEDUR PENGELUARAN KAS BELANJA LANGSUNG PADA KANTOR WILAYAH KEMENTERIAN AGAMA PROVINSI SULAWESI UTARA
Authors: Rawung Meliana , Runtu Treesje , Afandi Dhullo
Published: July 2023

Menerapkan sistem dan prosedur akuntansi pengeluaran kas sesuai dengan peraturan yang berlaku sangat penting bagi lembaga pemerintah karena bertujuan untuk menilai efektivitas sistem dan prosedur yang diterapkan serta memudahkan proses pengeluaran kas. Tujuan penelitian ini untuk menganalisis dan menguji kesesuaian prosedur pengeluaran kas belanja Langsung (LS) di Kantor Wilayah Kementerian Agama Provinsi Sulawesi Utara dengan Peraturan Menteri Keuangan No. 210/PMK.05/2022 tentang Tata Cara Pembayaran Dalam Rangka Pelaksanaan Anggaran Pendapatan dan Belanja Negara dan Peraturan Pemerintah Nomor 60 Tahun 2008 tentang Sistem Pengendalian Intern Pemerintah (SPIP). Jenis penelitian yang digunakan yaitu deskriptif kualitatif. Hasil penelitian yang diperoleh bahwa prosedur pengeluaran kas belanja Langsung (LS) di Kantor Wilayah Kementerian Agama Provinsi Sulawesi Utara disesuaikan dengan Peraturan Menteri Keuangan No. 210/PMK.05/2022 dan Peraturan pemerintah Nomor 60 Tahun 2008 sudah dilakukan dengan baik.
Kata Kunci: prosedur, pengeluaran kas, belanja
EFEK MODERASI TRANSPARANSI PADA HUBUNGAN KONEKSI POLITIK TERHADAP PENURUNAN HARGA SAHAM
Authors: Dewi Christine Novita , Stefani Ellen , Yuanita Dielanova Wynni
Published: July 2023

Penelitian ini bertujuan untuk menguji secara empiris pengaruh koneksi politik terhadap risiko penurunan harga saham. Penelitian ini menguji sampel yang telah dipilih secara purposive berjumlah 62 perusahaan yang terdaftar di Bursa Efek Indonesia periode tahun 2019-2020. Metoda analisis data menggunakan regresi linier berganda menunjukkan bahwa koneksi politik dapat mengurangi risiko penurunan harga saham, semakin tinggi koneksi politik, semakin rendah risiko penurunan harga saham dan sebaliknya. Ketika perusahaan yang memiliki koneksi politik melakukan transparansi laporan keuangan, maka risiko harga saham turun. Penelitian ini membuktikan bahwa ketika perusahaan tidak mampu menurunkan koneksi politiknya maka transparansi yang dilakukan perusahaan mampu untuk menurunkan risiko harga saham.
Polarization contributions to DC bias characteristics of nanograined BaTiO3-based ceramics
Authors: Teranishi Takashi , Ozaki Ruku , Kondo Shinya , Kishimoto Akira
Published: July 2023

The domain configuration contributions to the DC bias characteristics of nanograined BaTiO3 were clarified. Domain boundaries became more ambiguous with decreasing grain size (g.s.), whereas domain patterns partially vanished because of the reduction in BT ferroelectricity, in the g.s. range <1 μm. Additionally, intergranular stress increased with decreasing g.s., resulting in crystal lattice hardening in the vicinity of the domain walls (DWs) and suppression of dipole fluctuations in the DWs. These domain structural variations with the domain size (d.s.) reduced permittivity in the absence of a DC electric field, resulting in improvements in permittivity depressions in an electric field (Δε). Magnesium substitution slightly decreased the d.s. The increase in DW density upon Mg loading implied defect pairs,

Mg

Ti

"

–

V

o

•
•

,

which acted as new DW pinning centers, thereby subdividing the DWs. The Δε notably improved via Mg loading, because a defect pair effectively pins the DWs under the electric field.
GAMBARAN RESPON IMUN IgG IgM DENGUE DAN KADAR TROMBOSIT PADA PASIEN SUSPEK DBD DI KOTA KEDIRI
Authors: Erawati Erawati , Kusumawardani Siska , Umaya Dhenisa Na’im
Published: July 2023

Demam dengue merupakan infeksi demam yang disebabkan virus serotype DENV penularan melalui vector nyamuk Aedes  aegypti. Infeksi virus Dengue menyebabkan demam berdarah dengue (DBD) memicu tubuh untuk membentuk respon imun spesifik yaitu Imunoglobulin. Diagnosis imunoserologi demam dengue yaitu mengidentifikasi antibodi spesifik virus Dengue (IgM) dan (IgG) serta deteksi antigen NS1, penanda hematologi yaitu jumlah trombosit penderita rendah atau mengalami trombositopenia.. Gejala dari penyakit DBD yaitu demam suhu 38–40°C selama 2-7 hari, perdarahan dalam seperti di bagian gusi hidung (mimisan), muntah darah, bila diuji Rumpel Leede positif atau bintik merah (purpura), hepatomegali, nyeri otot, nyeri sendi, trombositopenia, mual, muntah, pucat, mengigil. Tujuan penelitian untuk menganalisis hasil pemeriksaan respon imun IgG IgM Metode Imunokromatografi dan kadar trombosit pada pasien suspek Demam dengue di RS Daha Husada kota Kediri. Jenis penelitian yaitu deskriptif. Teknik sampling menggunakan Accidental sampling, sampel sebanyak 22 sampel dan populasi   selama 3 bulan terakhir pada bulan Oktober-Desember 2021 75 pasien suspek DBD. Pemeriksaan IgG IgM imunokromatografi dan kadar trombossti menggunakan sampel whole blood pada pasien suspek Demam dengue. Prinsip pemeriksaan IgG IgM dengue yaitu metode uji kualitatif deteksi adanya perubahan warna pada strip test. Hasil pemeriksaan respon imun IgG IgM dengan metode imunokromatografi pada tanggal 23 Mei – 23 Juni 2022 di dapatkan hasil yaitu IgG dengue positif sebanyak 2 (9%), IgM dengue positif 2 (9%), IgG IgM dengue positif sebanyak 1 (5%) dan IgG IgM dengue negatif sebanyak 17  (77%). Kesimpulan penelitian yaitu kadar pasien yang mengalami trombositopenia ssebanyak 50% dan hasil pemeriksaan IgG IgM positif sebanyak 23%.
SKRINING FITOKIMIA EKSTRAK AIR DAUN TIN (Ficus Carica Lin.)
Authors: Kusumawardani Emi
Published: July 2023

Pendahuluan: Tanaman Tin (Ficus Carica Lin.) merupakan tanaman dimanfaatkan dalam pengobatan herbal dan telah terbukti khasiatnya dalam menangani berbagai masalah kesehatan diantaranya gangguan gastrointenstinal, penyakit kardiovaskular, inflamasi, gangguan pernapasan, penyakit ulseratif, dan kanker. Tanaman tin banyak dimanfaatkan pada bagian daun dan buah. Khasiat yang dimiliki oleh tanaman tin terutama daunnya diduga terdapat bermacam-macam komponen kimia yang terkandung dalam daun tin. Tujuan: Pada penelitian ini dilakukan skrining ekstrak air daun tin untuk mengetahui golongan senyawa yang terkandung dalam ekstrak.

Metode: Penelitian ini terdiri dari dua tahap yaitu ekstraksi dan skinning fitokimia. Proses ekstraksi dilakukan menggunakan metode freeze driying. Hasil: Skrining fitokimia pada ekstrak air daun tin meliputi pemeriksaan alkaloid, terpenoid, flavonoid, polifenol dan saponin. Kesimpulan: Hasil uji skrining fitokimia menunjukkan bahwa ekstrak air daun tin mengandung alkaloid, polifenol, dan saponin.
Kearifan Tradisional Orang Kayu Pulo dalam Menjaga Ekosistem Pesisir Kearifan Tradisional Orang Kayu Pulo
Authors: Yuliana Yuliana , Frank Simon Abdi K. , Poli Agustina Ivonne
Published: July 2023

Pemahaman tentang kearifan tradisional dalam menjaga ekosistem pesisir (lingkungan laut) sangat diperlukan. Karena kearifan tradisional atau kearifan lokal merupakan sebuah bentuk pengetahuan, pemahaman, keyakinan, wawasan dan adat istiadat atau kebiasaan yang menjadi pedoman bersikap dan berperilaku. Setiap komunitas tanpa terkecuali masyarakat pesisir pastinya memiliki bentuk-bentuk kearifan tradisional masing-masing yang diperoleh sebagai hasil pewarisan maupun dari proses belajar.  Melalui kearifan tradisional masyarakat dapat mengelola lingkungan hidup secara lestari dan berkelanjutan, sebagaimana dijelaskan pula dalam Undang-Undang Nomor 23 tahun 2009. Jenis penelitian ini adalah penelitian deskriptif kualitatif yang berlokasi di Kampung Kayu Pulo (Tahima Soroma) Distrik Jayapura Selatan, Kota Jayapura. Metode pengumpulan data dalam penelitian ini dilakukan dengan wawancara, observasi, dan dokumentasi. Prosedur pemilihan  narasumber dilakukan dengan cara snowball sampling. Tujuan penelitian ini adalah untuk mengetahui bentuk-bentuk kearifan Tradisional Orang Kayu Pulo dalam menjaga ekosistem Pesisir dan untuk mengetahui Faktor-faktor yang menghambat dan mendukung dalam usaha menjaga ekosistem Pesisir di Kampung Kayu Pulo .  Bentuk-bentuk  kearifan tradisional orang Kayu Pulo diantaranya: menggunakan alat tangkap ramah lingkungan, dan tidak mengotori lingkungan. Kebiasaan masyarakat di Kampung Kayu Pulo khususnya sebagai nelayan juga tergambar dari kemauan mereka untuk mematuhi peraturan tentang penggunaan alat tangkap yang dapat merusak ekosistem pesisir (laut). Kearifan tradisional orang kayu  Pulo dalam menjaga ekosistem pesisir berkaitan dengan pandangan  mereka tentang laut. masuknya modernisasi menjadi hal yang tidak dapat dihindarkan. Sebagai salah satu yang dapat menjadi faktor penghambat, modernisasi dapat mempengaruhi para generasi yang diharapkan dapat meneruskan  kearifan tradisionalnya. Sedangkan faktor pendukung adalah terkait dengan kepercayaan atau spiritual yang berhubungan dengan laut.
THE EFFECT OF USING TLSO (THORACAL LUMBAR SACRAL ORTHOSIS) ON ALIGNMENT KYPHOSIS IN THE ELDERLY
Authors: Ningsih Cica , Fathi Muhammad
Published: July 2023

Introduction: The alterations that occur in the vertebrae are Kyphosis, Lordosis, and Scoliosis. Kyphosis affects the majority of the elderly. Kyphosis is a type of deformity wherein the human spine becomes bent. The most frequent alterations in the vertebrae are atilted head forward (cervical kyphosis), an increase in the thoracic kyphosis curve, a flattened lumbar curve (lumbar kyphosis), and a reduction in the width of the intervertebral discus, resulting in a lower height. The focus of this research was to study the effects of TLSO on vertebral alignment postures in older people with kyphosis. Method: This research is a quasi-experimental research with one group pre and posttest design techniques. This research was conducted from March to October 2021 at the PosyanduLansia Sawahan, Ngemplak, Boyolali. Elderly who meet the requirements for this research subject include up to 30 elderly people. Each study subject will receive the TLSO intervention and then assess their spinal alignment before and after treatment.Paired Samples T-test was used to analyze the data in this study. Result: The application of TLSO had a statistically significant effect on alignment before and after the intervention (t = 35.98, mean difference = 8.34, and p value = 0.000). Conclusion: The use of TLSO has an impact on reducing spinal curvature so it is good for maintaining body posture according to normal alignment.
PENGARUH EKSTRAK KEMANGI (Ocimum sanctum Linn) TERHADAP PERTUMBUHAN JAMUR Candida albicans
Authors: Hermansyah Herry , Bianggo NauE Dian Adhe , Siregar Sri Sulpha , Wulandari Septi
Published: July 2023

Latar Belakang : Kemangi (Ocimum sanctum Linn) dapat dijadikan sebagai obat tradisional penyakit yang disebabkan oleh jamur Candida albicans. Penggunaanya dapat dilakukan dengan memakan langsung kemangi. Tujuan penelitian untuk mengetahui pengaruh ekstrak daun dan batang kemangi (Ocimum sanctum Linn) terhadap pertumbuhan jamur Candida albicans. Metode : Jenis penelitian Eksperimen. Sampel yang digunakan sebanyak 500 gram. Metode  pemeriksaan yang digunakan yaitu metode Kirby Bauer. Hasil : Hasil penelitian menunjukkan bahwa p value = 0,000 sehingga Ha diterima yang berarti ada pengaruh ekstrak daun dan batang kemangi terhadap pertumbuhan jamur Candida albicans. Dengan kekuatan efektifitas ekstrak daun dan batang kemangi terhadap pertumbuhan jamur Candida albicans sangat baik (R=0,951). Distribusi statistik rata-rata konsentrasi ekstrak daun dan batang kemangi yaitu 37,50% dengan median 37,50% serta standar deviasi 15,13%. Untuk konsentrasi minimumnya 15% dan konsentrasi maksimumnya 60%. Dengan estimasi interval 95% diyakini rata-rata konsentrasi ekstrak daun dan batang kemangi adalah 26,67% sampai dengan 48,32%. Distribusi statistik rata-rata diameter zona hambat yaitu sebesar 7,6 mm dengan median 7,5 mm serta standar deviasi 1,42 mm. Untuk diameter zona hambat minimumnya 6 mm dan maksimumnya 10 mm. Dengan estimasi interval 95% diyakini rata-rata diameter zona hambat adalah 6,57 mm sampai 8,6 mm. Kesimpulan : Ada pengaruh ekstrak daun dan batang kemangi (Ocimum sanctum Linn) terhadap pertumbuhan jamur Candida albicans, maka kemangi dapat dijadikan sebagai obat tradisional penyakit yang disebabkan oleh jamur Candida albicans.

Kata Kunci: kemangi, Candida albicans, zona hambat
ANALISIS JUMLAH TROMBOSIT PADA IBU HAMIL PREEKLAMSIA DI KOTA PALEMBANG TAHUN 2021
Authors: Oktavia Tiara , Febriyani Erisa , Garini Ardiya , Harianja Sri Hartini , Wulandari Septi
Published: July 2023

Latar Belakang: Preeklamsia merupakan kondisi pada ibu hamil dengan tekanan darah tinggi dan proteinuria tinggi pada akhir kehamilan atau lebih dari 20 minggu kehamilan. Preeklamsia menyebabkan disfungsi endotel, dan vasospasme atau vasokontriksi. Vasospame memicu agregasi trombosit sehingga menyebabkan penggunaan trombosit meningkat dan menyebabkan trombositopenia. Metode: Jenis penelitian yang digunakan deskriptif.  Populasi dalam penelitian ini adalah seluruh ibu hamil yang mengalami preeklamsia di RSIA Rika Amelia Kota Palembang tahun 2021 dan mempunyai rekam medis pemeriksaan jumlah trombosit dan diambil dengan teknik total sampling berjumlah 105 pasien. Pemeriksaan hitung jumlah trombosit menggunakan metode otomatik dengan alat hematology analyzer Dirui BCC-3600. Hasil: Didapatkan rata- rata jumlah trombosit 296.77 K/μl dengan jumlah trombosit terendah 107 K/μl dan jumlah trombosit tertinggi 548 K/μl. Berdasarkan umur, pada 35 ibu hamil preeklamsia dengan umur berisiko didapat rata- rata jumlah trombosit 277 K/μl sedangkan pada 70 pasien dengan umur tidak berisiko didapatkan rata- rata jumlah trombosit adalah 306 K/μl, dari pengujian T-test  di peroleh P value = 0,149. Berdasarkan usia kehamilan, pada 35 ibu hamil preeklamsia dengan usia kehamilan < 37 minggu diperoleh rata- rata jumlah trombosit adalah 306 K/μl sedangkan pada 70 ibu hamil preeklamsia dengan dengan usia kehamilan ≥ 37 minggu diperoleh rata- rata jumlah trombosit adalah 292 K/μl, dari pengujian T-test  di peroleh P value = 0,514 Kesimpulan: Tidak ada perbedaan yang signifikan terhadap jumlah trombosit pada ibu hamil preeklamsia berdasarkan umur ibu dan usia kehamilan.
APPLICABILITY OF THE INTEGRATED NEONATAL CHOLESTASIS CARD AT A TERTIARY CARE CENTRE FROM INDIA
Authors: Jain Priyam , Kumar Singh Sumit , Kela Gunjan
Published: July 2023

Objectives: Delay in detection of Neonatal Cholestasis (NC) results in late referral of treatable causes of
NC hampering the timely intervention. To overcome this by early detection of NC, an integrated NC card
incorporating urine color was developed in India recently. This study was aimed to assess the applicability of integrated NC
card. An analytical cross-sectional study was carried out at a tertiary care institute over Methods: a period of 18 months. Study
participants were divided into 3 groups. Group A: infants with cholestasis, Group B: infants with unconjugated
hyperbilirubinemia and Group C: healthy infants visiting the immunization clinic. Real-time stool and urine color of all study
participants were assessed using integrated NC card by care-takers (mother) and the study investigator separately and
documented for comparative analysis. A total of 130 subjects (Group A: 30; Group B: 50; Results: Group C: 50). were enrolled in
study. The median age of children with in group A was 45 (28-125 days), Group B was 6 (2-50) days and Group C was 85 (40-185)
days. Measure of agreement between investigator and care-takers: For dark yellow urine in group A: 93%, kappa=0.634; for
normal urine in group B and C: 96%, Kappa= 0.648 and 98%, kappa=0.847 respectively. For pale stool in group A: 85%,
kappa=0.550; for normal stool in group B and C: 93%, kappa= 0.623 and 96%, kappa=0.730 respectively. The Conclusion:
integrated NC card was found useful in detection of NC based on urine color and differentiate it from unconjugated
hyperbilirubinemia
GALL BLADDER PARAGANGLIOMA - A RARE AND PRECARIOUS DIAGNOSIS - A CASE REPORT AND REVIEW OF LITERATURE
Authors: Kapoor Rohit , Sapharullah Safarudeen , Shrawan Nijhawan Vijay , Dhawan Vishesh , Kirti Shubh
Published: July 2023

Introduction: Neuroendocrine neoplasm (NET) of the gallbladder is an extremely uncommon diagnosis. We present a case of a benign gallbladder paraganglioma which should be differentiated from malignant NET. A 63-year-old female came to surgical clinic with complaints of recurrent biliary co Case Presentation: lic which aggravated on taking fatty food and relieved on medication. She was admitted in surgical ward and routine blood investigations and imaging work up was done. USG whole abdomen was consistent with cholelithiasis. She underwent elective laparoscopic cholecystectomy under General anaesthesia. Intra operative and post operative period were uneventful. Histopathological examination report revealed chronic cholecystitis with paraganglioma in the gall bladder Discussion: Neuroendocrine neoplasms of the gallbladder is a rare nding. Their management includes simple cholecystectomy and radical resections in advanced cases and chemotherapy. On the contrary gall bladder paraganglia is a benign entity which is managed with cholecystectomy. A neuroendocrine neoplasm of the gallbladder may closely resemble a b Conclusion: enign paraganglion. If a NET is suspected, one should be aware of benign paraganglioma entity
CLINICAL EVALUATION AND PATCH TESTING IN HAND ECZEMA
Authors: Jaiswal Ruchi , Damor Nilam , Baria Mohabatsinh
Published: July 2023

Hand eczema is one of the most common occupational dermatological condition. Chronicity and recurrence nature of hand eczema leads to loss of work and quality of life of workers. In order to identify the causative factor patch test could be relevant test. Out of 340 employees screened, 46 employees (13.5%) suffered from hand eczema. The most common type was wear and tear dermatitis accounting for 17 (36.9%) cases, followed by discoid eczema, pompholyx, focal palmar peeling, nger-tip eczema, hyperkeratotic eczema, ring eczema, and unspecied types. Patch testing was positive in 15 (32.6%) cases. The most common allergen was paraphenylene diamine, followed by fragrance mix, nitrofurazone, mercaptobenzothiazole, potassium bichromate, black rubber mix, and thiuram mix. A statistically signicant association (0.001) was found with an underlying history of atopy.
A COMPARATIVE STUDY OF OPEN HAEMORRHOIDECTOMY AND STAPLED HAEMORRHOIDOPEXY
Authors: Sheth Dhruvesh , Patel Nirmal , Patel Jatin , Chauhan Pratap
Published: July 2023

Introduction: Haemorrhoids or 'Piles' is a frequently observed disease in surgical practice. Various nonsurgical and surgical treatments are available. Open haemorrhoidectomy (Milligan-Morgan) is a widely used procedure. A recent novel technique called 'Stapled haemorrhoidectomy', rst described and performed by Italian surgeon Antonio Longo is gaining worldwide recognition for its benets. Aim: To compare Stapled haemorrhoidectomy with open (Miligan Morgan) haemorrhoidectomy in terms of post-operative pain, resumption of daily activity, hospital stay, postoperative bleeding, urinary retention and anal incontinence. Study Design: Prospective, comparative study from May 2022 to April 2023. Materials and Methods:A total of 80 patients between the age group of 20 and 70 years, diagnosed to have grade III or IV haemorrhoids were included in the study, divided into 2 groups, Group 1 undergoing Open haemorrhoidectomy (40 patients) and Group 2 undergoing Stapled haemorrhoidectomy (40 patients). Post operatively patients of both groups were reviewed at the time of discharge. All patients were given a questionnaire and data collected verbally and analysed statistically. Comparative analysis between the two groups were done based on Independent students 't' test. Results: The mean age of patients in Open haemorrhoidectomy (OH) group was 42.2 and Stapler haemorrhoidectomy (SH) group was 38.5. 86.6% were males and 13.4% were females in OH group, 90% were males and 10% were females in SH group. Post-operative bleeding in both OH and SH group had an incidence of 2%. Post-operative urinary retention was seen in 4% and 8% in OH and SH group respectively. In both groups, post-operative anal incontinence was not seen. Based on Independent sample 't' test the post-operative pain, Post-operative hospital stay and duration of resumption of daily activity was less in SH group compared to OH group and statistically signicant with p<0.001. However, complications like post-operative bleeding, urinary retention and anal incontinence are almost same in both the groups Conclusion: Stapled Haemorrhoidectomy is less painful with shorter duration of hospital stay and resumption of daily activity is faster than the open haemorrhoidectomy. However, long term follow-up is required to know the recurrence rate in stapled haemorrhoidectomy
ANAESTHETIC CARE OR MANAGEMENT OF PATIENT WITH CHD - DOUBLE OUTLET RIGHT VENTRICLE ( DORV) POSTED FOR EMERGENCY CRANIOTOMY AND EVACUATION FOR RECURRENT CEREBRAL ABSCESS
Authors: C Rao Archana , Padur Tantry Thrivikrama , C Mahima
Published: July 2023

Intracranial lesions frequently occur in association with congenital malformation of the heart. With increasing diagnostic modalities, more patients with congenital heart disease (CHD) survive till adulthood and may present for coincident elective or emergent non-cardiac surgery. Providing general anaesthesia for these cases is a challenging task for anaesthesiologist with limited facilities and resources available . We report the anaesthetic
care/management of patient with CHD - double outlet right ventricle (DORV) who underwent emergency craniotomy and evacuation for recurrent cerebral abscess.
CARBAPENEM RESISTANT ACINETOBACTER BAUMANNII - A CHALLENGING THREAT IN HEALTHCARE
Authors: Sardana Vandana , Rajeev Verma Sameer
Published: July 2023

Introduction: Carbapenem resistant Acinetobacter baumannii (CRAB) has emerged worldwide, as an alarming pathogen causing healthcare associated infections. It mostly involves patients with impaired host defenses, and those with debilitating illnesses. CRAB is declared as the top priority pathogen by the World Health Organization for the development of new drugs. Aims & Objectives: i) To determine the frequency of isolation of Acinetobacter baumannii from clinical samples ii) To detect carbapenem resistance in clinical isolates of A. baumannii iii) To understand the risks factors associated with acquisition of CRAB. Methods: The clinical samples were subjected to culture i) by conventional methods as per standard bacteriological techniques, and ii) by an automated BACTEC System (BD). The isolates grown onto culture media were identied i) by conventional methods, and ii) by an automated VITEK 2 system (Biomerieux). Antibiotic susceptibility testing was performed i) by the Kirby Bauer disc diffusion method as per CLSI guidelines, and ii) by VITEK 2 system. All the meropenem resistant isolates of A. baumanni were subjected to i) Modied Hodge Test (MHT) for the production of carbapenemase, and ii) Combined Disk Test (CDT), using imipenem and EDTA, for the production of metallo-betalactamase. Results: The frequency of isolation of Acinetobacter species was found to be 5.7%, of which the predominant was A. baumanni (89.3%). Among the isolates of A. baumannii, the frequency of meropenem resistance was found to be 72.1%. Meropenem resistant isolates of A. baumannii were most commonly obtained from patients admitted in intensive care units (86.3%). CRAB isolates were most frequently recovered from endotracheal aspirate (34.2%), followed by pus (29.8%), blood (20.7%), sputum (8.2%) and urine (5.6%) The most common risk factor associated with CRAB was mechanical ventilation (35.5%), followed by previous antibiotic usage (28.5%), indwelling catheters (11.1%), prolonged hospitalization (9.7%), chronic obstructive pulmonary disease (8.1%) and diabetes (5.7%). Out of 922 CRAB isolates, 757 (82.1%) were carbapenemase producers. Among the CRAB isolates, 31.9% were found to be only MHT positive, 26.7% were only CDT positive, 23.5% were both MHT and CDT positive, and the remaining 17.9% were both MHT and CDT negative. Conclusion: Emergence of infections with CRAB emphasizes the need for continuous surveillance, judicious use of antibiotics, and implementation of aggressive infection control strategies.
COMPARISON BETWEEN MODIFIED ALVARADO AND RIPASA SCORING SYSTEM IN DIAGNOSING ACUTE APPENDICITIS
Authors: G. P. Nair Indran , Sajan Stanly , Ramaswamy Prahaladh , R. Eashwar Maniyen S.
Published: July 2023

Background: The most frequent emergency surgery is an emergency appendectomy, which is one of the most prevalent causes of acute abdominal pain. A clinical scoring system is the less expensive, quicker, and non-invasive diagnostic technique for identifying acute appendicitis. In order to aid in the diagnosis of an acute appendicitis and reduce unnecessary exploration, scoring systems based on the history, clinical examination, and essential investigations are available. Aim: The aim of the present study was to compare the Modied Alvarado scoring system (MASS) and the Raja Isteri Pengiran Anak Saleha Appendicitis score (RIPASA score) and to determine their diagnostic accuracy. Materials and Method: A prospective observational study was conducted in the Department of General Surgery, Sree Mookambika Institute of Medical Sciences, Kulasekharam for a period of one year. A total of 80 cases were included in the study. Alvarado and RIPASA scores were calculated. Diagnosis was conrmed on histopathological evaluation. Results were analysed using SPSS 20.0 version and the association was tested using Chi square test. The scores were compared based on sensitivity, specicity, Positive Predictive Value (PPV), Negative Predictive Value (NPV) and diagnostic accuracy. Results: Among the 80 patients, based on the Modied Alvarado score, 61(76.25%) patients and in RIPASA score 70(87.5%) patients clinically had appendicitis. On histopathological examination it was found that 70(87.5%) of the patients were diagnosed to have acute appendicitis. The sensitivity, specicity, PPV, NPV and diagnostic accuracy for RIPASA score were 98.57%, 90%, 98.57%, 90% and 69.11% respectively. This was higher than the sensitivity, specicity, PPV, NPV and diagnostic accuracy for Modied Alvarado score which was 82.86%, 70%, 95.08%, 36.84%, 58.08% respectively. Conclusion: When comparing the RIPASA score to the modied Alvarado score in diagnosing acute appendicitis, the RIPASA score was better. The Fourteen parameters have been made available in a thorough clinical history as well as evaluation and can be used quickly and readily. As a result, a management choice can be taken quickly. Thus, appendicitis-related mortality and morbidity can be decreased
A STUDY TO ASSESS QUALITY OF LIFE OF ELDERLY RESIDING IN FIELD PRACTICE AREA OF URBAN HEALTH TRAINING CENTER OF SMS MEDICAL COLLEGE JAIPUR
Authors: Lal Damor Keshu , Kumar Sonkaria Lokesh , Kewalramani Suresh , Sidhu Japneet , Lal Sohan
Published: July 2023

Background: In India, as per the “National Policy on Older People” a senior citizen is dened as a person
who is 60 years old or above. The World Health Organization (WHO) in 1998 dened Quality of Life as:
“The individual's perception of his or her position in life, with in the cultural context and value system he or she lives in, and in
relation to his or her goals, expectations parameters and social relations”. As per the WHO report (2013), there are more than
600 million elderlies at a global level. The elderly population will be doubled by 2025 and rise to two billion by 2050. According
to the 2001 census, India was home to more than 77 million people aged 60 years and over. One of the greatest tasks of public
health is to improve the Quality of Life (QOL) of geriatric population through which we can increase the life expectancy of the
elderly by every year. Aim and Objectives: To know the quality of life of the elderly and its inuencing socio-demographic
factors living in urban eld practice area, Jaipur city with objectives like assess and compare the quality of life and sociodemographic factors affecting quality of life of elderly Materials and Methods: Urban eld practice area is divided into 4 areas
namely Katputli Nagar, Bais godown, Susheel Pura and Bhojpura covers a population of 15190. Of these, 25 elderlies from each
area were systemic randomly selected and interviewed to complete the sample of 100 people. A pretested semi-structured
questionnaire having two sections was used to collect the information where the rst part included information regarding
sociodemographic prole and the second part comprised of a 26-point WHOQOL -BREF questionnaire. Results: A maximum
proportion of the study subjects was male (65%) with age group of 60-69 years is 69% and ≥70 years is 31%. In regards to
educational status 38% were illiterates, literacy is high in urban area with 62% participants were literate. Most of subjects
belonged to middle class (45%), upper middle class (35%) of socioeconomic status (SES-III) and least in lower middle (4%)
(Modied BG Prasad's classication). Perceived Quality of Life (QOL) were 46% good for elderly living in urban area. While in
area subject only 13% perceive poor QOL and 33% perceived neither poor nor good QOL while only 52% has satised QOL. In
urban area highest mean score present in psychological domain (66.18 ± 8.274) and lowest in environmental domain (60.65 ±
9.691) of QOL. Conclusions: Quality of life is a multidimensional concept. Education and nancial dependency were found to
be the possible determinants of QOL. More extensive studies are recommended to identify other factors affecting QOL.
A CASE REPORT ON ADRENAL INCIDENTALOMA- ASSESSMENT AND MANAGEMENT
Authors: C Rao Archana , Padur Tantry Thrivikrama , C Mahima
Published: July 2023

Adrenal masses are often discovered incidentally in imaging performed for some other reason unrelated to adrenal pathology. Screening for pheochromocytoma is essential in
all cases due to its varied presentation. Careful preoperative assessment and perioperative management is vital to avoid morbidity. Here we are reporting a case of adrenal incidentaloma posted for laparoscopic adrenalectomy. The case was challenging to the anaesthesiologist in view of theuctuating hemodynamic status intraoperatively and
postoperatively
A STUDY OF IMMUNOHISTOCHEMICAL EXPRESSION OF GALECTIN-3 IN NONNEOPLASTIC AND NEOPLASTIC LESIONS OF THYROID
Authors: Ajay Kumar Singh , Kanchan Srivastava , Shaila K Mitra, , Archana Bundela, , Shilpa U Vahikar, , Alpana Bundela, , Shubham Mishra,
Published: July 2023

Introduction: Thyroid lesions are fairly common and have a wide spectrum of diseases ranging from functional, immune mediated to neoplastic lesions. Malignancy of thyroid constitutes approximately 1% of all cancers. These malignant tumors of thyroid gland exhibit a variety of histopathologies and clinical behavior. Immune markers are gaining more and more importance in diagnostic pathology, especially in the differential diagnostics and in the grading of thyroid gland tumors. In the recent times Galectin-3 has received notable recognition for its usefulness as a diagnostic marker for thyroid cancer. Aims and objectives: To evaluate the diagnostic role of galectin-3 (Gal-3) in differentiating malignant from benign thyroid neoplasm. In this observational study, we evaluated Material and method: Gal3 expression in a spectrum of all non-neoplastic and neoplastic lesions including benign and malignant lesions of thyroid gland. All types of thyroidectomy specimens were xed in 10% formal saline and subjected to histopathological examination. Sections were stained with H&E stain. Gal-3 immunoperoxidase reaction was carried out in histological sections from all the cases and descriptive analysis was done. In the study of 100 cases of thyroid swelling w Result: ere included and evaluated by histopathological and by using Gal-3 immunoperoxidase marker. Out of 100 cases, majority of thyroid lesions were seen in females with 76 cases (76%) while only 24 cases (24%) were seen in male. Among 66 non-neoplastic cases, only 6 cases (9.1%) and among 34 neoplastic lesions, 28 cases (82.4%) were positive for galectin-3 marker. Statistical signicance of galectin-3 expression between non-neoplastic and neoplastic thyroid lesions found to be statistically signicant (P value <0000.1). The sensitivity and specicity of galectin-3 detection of malignant lesions were found to be 82.4% and 91% respectively with 82.4% positive predictive value and 90.9% negative predictive value. We suggest that Galectin- Conclusion: 3 expression is helpful in enabling better diagnosis and patient care by guiding appropriate therapeutic decisions.
EPIGENETICS, SOCIAL DETERMINANTS AND TRANSFORMATION – NATURE AND NURTURE
Authors: Pandey Vinita
Published: July 2023

There is emerging scientic research and evidence which visibly demonstrates that internal body environmental inuences can not only impact genes but also how they are expressed. Scientists have discovered that early experiences can determine how genes are turned on and off and even whether some are expressed at all. Epigenetics is the study of how behaviours and environment can cause changes that affect the way the genes work. Unlike genetic changes, epigenetic changes are reversible and do not change the DNA sequence, but they can change how our body reads a DNA sequence. There is strong inuence of the epigenetics on social life. The ancient Indian systems of Ayurveda and Yoga indeed have strong bases for the same. It would be appropriate to further explore the same through inter disciplinary research