bluuebunny/crossref_metadata_2025 huggingface dataset:
An Assessment of Seasonal Water Quality in Phewa Lake, Nepal, by Integrating Geochemical Indices and Statistical Techniques: A Sustainable Approach
Authors: Timalsina Rojesh , Acharya Surendra , Đurin Bojan , Awasthi Mahesh Prasad , Pant Ramesh Raj , Joshi Ganesh Raj , Byanju Rejina Maskey , Panthi Khim Prasad , Joshi Susan , Kumar Amit , Thakur Tarun Kumar , Saqr Ahmed M.
Published: January 2025

Lakes are vital freshwater ecosystems that sustain biodiversity, support livelihoods, and drive socio-economic growth globally. However, they face escalating threats from anthropogenic activities, including urbanization, agricultural runoff, and pollution, which are exacerbated by climate change. Phewa Lake in Nepal was selected for this study due to its increasing rates of nutrient enrichment, sedimentation, and pollution. This study evaluated seasonal and spatial water quality variations within the lake by analyzing water samples from 30 sites during the pre-monsoon and post-monsoon seasons. Twenty physicochemical parameters, including the potential of hydrogen (pH), dissolved oxygen (DO), electrical conductivity (EC), and major ions, e.g., calcium (Ca2+), magnesium (Mg2+), sodium (Na+), potassium (K+), bicarbonate (HCO3−), chloride (Cl−), sulfate (SO42−), nitrate (NO3−), phosphate (PO43−), and ammonium (NH4+), were measured. The average pH ranged from 8.06 (pre-monsoon) to 8.24 (post-monsoon), reflecting dilution from monsoon rains and increased carbonate runoff. Furthermore, the DO levels in Phewa Lake averaged 7.46 mg/L (pre-monsoon) and 8.62 mg/L (post-monsoon), with higher values observed post-monsoon due to rainfall-driven oxygenation. Nutrient concentrations were shown to be elevated, with the nitrate concentration reaching 2.31 mg/L during the pre-monsoon period, and the phosphate concentration peaking at 0.15 mg/L in the post-monsoon period, particularly near agricultural runoff zones. The dominant cations in the lake’s hydrochemistry were Ca2+ and Mg2+, while HCO3− was the primary anion, reflecting the influence of carbonate weathering. Cluster analysis identified the lake outlet as a high-pollution zone, with the total dissolved solids (TDS) reaching 108–135 mg/L. Additionally, Principal component analysis revealed agricultural runoff and sewage effluents as the main pollution sources. Seasonal dynamics highlighted monsoon-induced dilution and pre-monsoon pollution peaks. These findings underscore the need for targeted pollution control and eutrophication management. By aligning with the sustainable development goals (SDGs) relevant to clean water and climate action, this research provides a replicable framework for sustainable lake management that is applicable to freshwater ecosystems worldwide.
Effects of Gradient Warming on Carbon and Water Fluxes in Zoige Plateau Peatland
Authors: Yu Xiaoshun , Hao Yanbin , Yan Zhongqing , Li Yong , Yang Ao , Niu Yuechuan , Liu Jinming , Kang Enze , Zhang Kerou , Yan Liang , Zhuang Weirong , Zhang Xiaodong , Kang Xiaoming
Published: January 2025

Water use efficiency (WUE) plays a pivotal role in connecting the carbon and water cycles and represents the amount of water used by plants or ecosystems to achieve carbon sequestration. The response of WUE to climate warming and its underlying mechanisms remain unclear. Here, we examined the effects of varying levels of warming on carbon fluxes, water fluxes, and WUE in an alpine peatland, with Blysmus sinocompressus and Carex secbrirostris as dominant species. Open-top chambers were utilized to simulate two levels of warming: low-level warming (TL) and high-level warming (TH). The carbon dioxide and water fluxes were monitored over a growing season (June to September). Gradient warming significantly decreased both gross primary productivity (GPP) and net ecosystem carbon exchange (NEE); GPP was 10.05% and 13.31% lower and NEE was 21.00% and 30.00% lower in the TL and TH treatments, respectively, than in the control. Warming had no significant effect on soil evaporation, and plant transpiration and evapotranspiration were 36.98% and 23.71% higher in the TL treatment than in the control, respectively; this led to decreases of 31.38% and 28.17% in canopy water use efficiency (WUEc) and ecosystem water use efficiency (WUEe), respectively. Plant transpiration was the main factor affecting both WUEe and WUEc in response to warming. The findings underscore the essential function of water fluxes in regulating WUE and enhance our understanding of carbon–water coupling mechanisms under climate change.
Digitalization of production to increase efficiency at Unisoft
Authors:   Russia, Yekaterinburg, Onosov A.G.
Published: January 2025

The article discusses the experience of digitalization and automation of production
processes at Unisoft, a supplier of plastic cards and printed products in Russia. The company
sought to improve the efficiency and quality of its services in the face of growing competition.
The implementation of the PrintEffect printing house management system allowed Unisoft
to optimize production, improve order management, reduce losses and increase labor
productivity. Particular attention is paid to the challenges that the company faced on the
path to digitalization and how they were successfully overcome thanks to the professionalism
and dedication of the company's team. The article describes in detail the stages of system
implementation, PrintEffect functions and the achieved results, which confirmed the
importance of digital technologies for modern business.
Industry as a Basis for Economic Well-Being. The Case of Vladimir Region
Authors:   Special Economic Zone Dobrograd-1, Zimina N.E.
Published: January 2025

The article examines the role of industry in the economic development of the Vladimir
region. Industry is a key factor in the region's growth, providing jobs, fi lling the budget and
contributing to the development of the social sphere. The region has rich historical experience
in industrial production, a combination of traditional and modern industries, as well as strong
human resources. Special economic zones such as Dobrograd-1 and the Vladimir SEZ play
an important role in attracting investment and developing new industries, which aff ects the
improvement of the population's standard of living.
Staff shortage: how freelancers can solve business problems
Authors:   Qugo, Russia, Moscow, Znak I. L.
Published: January 2025

The article examines the issue of staff shortage. Previously, it was experienced by
companies that provide seasonal services. For example, in the summer, ice cream sellers and
employees at seaside hotels are needed, in the winter, ski resorts, skating rinks and other
entertainment facilities experience a staff shortage. In the last few years, staff shortages are no
longer periodic. More and more companies complain about turnover: good specialists move
to other companies, and new ones have to be trained, who also do not work long. Why does
this happen? There can be many reasons: from uncompetitive salaries to diffi cult working
conditions. To solve the issue of staff shortage, you must fi rst understand why this is happening
in your company. After that, try to improve social guarantees and provide additional benefi ts
for employees. But what to do if there is a lot of work, but not enough employees? In this
situation, the employer should pay attention to freelancers. This will help to temporarily close
the «gaps» in personnel. To register freelancers, you can use diff erent methods of cooperation:
from outsourcing to drawing up a civil-law contract with the self-employed. The main thing is
to correctly formalize such cooperation and submit reports on time.
EFEKTIVITAS DISCHARGE PLANNING TENTANG PERAWATAN LUKA TERHADAP PENYEMBUHAN LUKA PADA PASIEN SECTIO CAESAREA
Authors: Basri Basri , Wibowo Harry Permana
Published: January 2025

Sectio caesarea (SC) is a surgical process to deliver a fetus through incisions made in the abdominal wall and uterus so that the fetus can be born healthy and intact. Caesarean section has life-threatening risks, one of which is the risk of infection. The quality of wound care must not decline after the patient is discharged, follow-up care at home will be very important. The aim of this study is to determine the effectiveness of discharge planning regarding wound care for wound healing in Sectio caesarea patients. This research was conducted at the BLUD of RSU Cut Nyakdhien Meulaboh. This type of research uses a quantitative method with a quasi-experimental design through a one group pre-test post-test design approach. The research population was 35 people. The sampling technique uses saturated sampling. The instrument in this study used a questionnaire filled out by respondents and observation sheets. Data analysis using univariate and bivariate. Bivariate analysis using paired t-test (Paired T-Test). The results showed that the majority of wound healing before discharge planning was carried out was good. Wound healing after the majority of discharge planning was carried out very well. The significance value of p-value = 0.000 (p <0.05) then H0 is accepted. This means that there is effectiveness of discharge planning regarding wound care for wound healing in Sectio caesarea patients. It is suggested that this study can provide additional references for future research to discuss more broadly the factors that accelerate wound healing in Sectio caesarea patients.
Analysis of Factors Related to The Mental Status of Elderly
Authors: Devita Yeni , Nita Yureya , Dwiguna Stephanie , Puswati Desti , Saputra Rahmat , Alfianur Alfianur
Published: January 2025

Mental health problems can have a significant impact on elderly. Some things related to mental disorders, such as depression and dementia in elderly, are caused by several factors, including elderly independence, family support, work, health or diseases suffered by elderly, and environment. This study aimed to determine the aspects related to the mental status of older people. This type of research is quantitative research. The population in this study is all elderly who are in the working area of UPT Puskesmas Bangko Jaya. The sampling technique uses probability sampling with a simple random sampling approach with 96 elderly samples. The analysis used is a bivariate analysis using the Chi-Square statistical test. The results showed that there was a correlation between the independence of elderly and the mental status of elderly (p-value = 0.026 < α = 0.05), There was a correlation between family support and the mental status of elderly (p-value = 0.014 < α = 0.05), There was a correlation between the history of illness and the mental status of elderly (p-value = 0.000 < α = 0.05) and There was a correlation between the elderly environment and the mental status of elderly (p-value = 0.037 < α = 0.05). The nursing profession was expected to provide advocacy and assistance to health workers in primary care, especially nursing, to improve the mental status of elderly.
Facebook Addiction, Game online, Physical Health Among Indonesian Students
Authors: Hutapea Dwight Mahaputera Marulitua , Sitopu Robin Ferdiansyah , Silalahi Kristina L , Halawa Afeus , Munthe Dewi Sartika , Siregar Ryskina Fatimah
Published: January 2025

This study is essential for students to know about Facebook addiction, Game online, and physical health. The study aims to describe the level of Facebook addiction, play online, and physical health and examine their relationship. The total sample was 206 people selected using the purposive sampling method. The research design was correlational; two hundred-six participants joined this study. Each participant filled out all of the questionnaires (demographic data, the Bergen Facebook Addiction (BFAS), Game Addiction (GAS), and Physical Questionnaire (PHQ). All questionnaires were taken from the previous research and validated; the reliability test was high. Based on the Pearson correlation tests, relationships were shown between Facebook addiction, games online, and physical health. There is a significant positive correlation between Facebook addiction and physical health and games online and physical health. Facebook addiction has a positive impact on physical health. Facebook addiction will impact a student's physical health. This study findings that Facebook addiction is low level, game online moderate level, and moderate level of physical fitness. The best way to prevent students from Facebook addiction is to make them busy with school activities. Games online also have a positive impact on physical health. The longer we play the Game online, the more physical health problems we will have. Say no to Facebook addiction and games online.
Description of Complementary Feeding Under-Five Children with the Incidence of Stunting
Authors: Lingga Rugun Togianur , Sihombing Lentina , Silaban Jojor , Silaban Verawaty Fitrinelda
Published: January 2025

The government has made various efforts to reduce the incidence of stunting in children under five, but to date, it has not shown maximum results. Stunting is a condition where a child has a shorter height than children of the same age, which means that the child's height is below the normal value. Efforts are made to reduce the prevalence of stunting, among others, by monitoring child growth and development, organizing supplementary feeding activities, or providing MP-ASI. Complementary feeding is food or drink that contains energy and nutrients given to infants or children aged 6-24 months to meet nutritional needs other than breast milk. The purpose of the study was to determine the description of complementary feeding in under-fives with the incidence of stunting. This study used descriptive quantitative research methods with a population of 43 stunted clowns using a total sampling technique. The results showed that the description of the provision of complementary foods for stunting was mostly lacking (69.7%) and the incidence of stunting showed a short category (76.7%) and very short (23.3%). Suggestions. Provide health education about complementary feeding for infants and health education about stunting to parents, especially mothers.
Assessing the Direct Impact of Typhoons on Vegetation Canopy Structure and Photosynthesis
Authors: Zheng Yaoyao , Zhan Simin , Zhu Zaichun , Cao Sen , Chen Jiana , Zhao Pengjun , Wang Weimin , Myneni Ranga B.
Published: January 2025

Typhoons are undergoing changes in frequency, intensity, and landward movement due to climate change, placing coastal vegetation ecosystems at heightened risk. These ecosystems provide critical ecological, social, and economic functions, making accurate assessment of typhoon impacts essential for effective management and disaster risk reduction. Traditional methods for assessing typhoon impacts on large-scale vegetation often compare pre- and post-typhoon satellite images. These do not account for natural variations in plant life cycles or interannual variations in environmental conditions, potentially leading to inaccurate assessments of typhoon-induced vegetation damage and recovery. This study proposes a novel framework for quantifying typhoons’ immediate and long-term impacts on vegetation canopy structure and photosynthesis. We developed random forest models based on satellite-observed leaf area index (LAI) and environmental data during typhoon-free periods to simulate LAI under non-typhoon conditions. The simulated LAI time series was then compared with the satellite-observed typhoon-affected LAI to assess the typhoon-induced canopy loss and recovery, which was then used to estimate the typhoon-caused photosynthesis loss and recovery with 2 widely used light-use efficiency models. The framework was applied to 3 super typhoons that traversed the Greater Bay Area. Typhoons Nida, Hato, and Mangkhut caused canopy losses in 76.58%, 61.25%, and 89.67% of vegetated regions, respectively, leading to direct cumulative gross primary production losses of 0.36, 0.22, and 0.50 Tg C. The proposed framework establishes a pivotal foundation for future modeling and assessment of direct vegetation damage attributed to typhoons, providing scientific support for vegetation management and disaster risk reduction in coastal areas.
Application of Therapeutic Hot and Cold Agents Result in Altered Measurement of Skinfold Thickness
Authors: Lennie Susan , Garden Lia , Hall Andy
Published: January 2025

Introduction: Accurate determination of body composition is crucial for athletic assessment and training. The International Society for the Advancement of Kinanthropometry suggest that skinfold measurements may be affected by conditions such as recent training, competition, sauna swimming or showering, as heat may increase values due to an associated increase in blood flow; however this effect has not previously been demonstrated. Methods: This intervention trial, with crossover design, aimed to investigate the effect of modified skin surface temperatures following topical thermal applications on skinfold thickness at the bicep and tricep. Skinfold thickness (SF) and skin surface temperature pre- and post-application of a heated pad and cold gel pad was recorded in 54 young adults. Results: Heat application led to a small, but significant, reduction in tricep SF and no significant change in bicep SF, while cold application resulted in a small, but significant, increase in bicep SF but not tricep SF. These changes may be attributed to alterations in tissue extensibility and creep rate. Conclusions: This study indicates that topical application of heat or cold can influence skinfold measurement, highlighting the importance of standardising measurement conditions. However, further research is needed to clarify whether this is a biological effect or a technical error of measurement.
Rasch Analysis on Video-based Assessment for Detecting Errors in Performing Activities of Daily Living for Older People with Dementia
Authors:   Society of Occupational Therapy for the Aged and Dementia, Jung Nam-Hae , Cho Mi-Lim
Published: January 2025

Objective : This study aims to verify the construct validity of the VADCE-ADL tool through Rasch analysis.
Methods : The VADCE-ADL comprised 40 videos of errors frequently seen during ADL in older people with dementia. One hundred and fifteen older Korean adults watched the videos and verbally expressed what the errors were. The understanding level was scored on a 4-point scale. Descriptive statistics, frequency analysis, and reliability analysis were conducted using SPSS 25.0, and participant and item suitability and item difficulty were analyzed using Winstep 5.7.4.
Results : The internal consistency of VADCE-ADL was 0.916. Participant suitability analysis found no un-suitable individual. Item suitability analysis found three inappropriate items including ‘no significance for safety,’ ‘difficulty in distinguishing bath products,’ and ‘difficulty in controlling the amount.’ As a result of analyzing the difficulty level of the items excluding the three inappropriate items, the items with high difficulty were ‘errors in managing personal items,’ ‘not flushing the toilet after us-ing the toilet,’ ‘lack of awareness of other people's emotions,’ ‘difficulty finding space in the house,’ and ‘excessive respect for others.’
Conclusion : VADCE-ADL presents a promising approach to assessing error detection abilities in older adults dur-ing ADL, offering a time- and energy-efficient alternative to traditional performance-based tools. However, to maximize its effectiveness, improvements in animation design, scenario realism, and item calibration are essential
The Effects of a Traditional Play Application on Cognitive Function, Depression, and Quality of Life in an Elderly Individual with D ementia: A S ingle-Subject Study
Authors:   Society of Occupational Therapy for the Aged and Dementia, Lee Ah-Young , Yang Yeong-Ae
Published: January 2025

Objective : This study aims to examine the effects of a traditional play application on cognitive function, depression, and quality of life in an elderly individual with dementia.
Methods : The study was conducted from November 4 to December 2, 2024, involving a 75-year-old elderly individual with dementia, who was hospitalized at Hospital A. The participant used the traditional play application for 30 minutes a day, three times a week, for a total of 12 sessions over four weeks. The research design employed a single-subject experimental research design (AB design). Assessments were conducted at four time points: baseline (A), 1 week after the intervention (B-1), 2 weeks after the intervention (B-2), and at the end of the intervention (B-3),
measuring cognitive function, depressive symptoms, and quality of life.
Results : The standard scores of ognitive function, depression, overall quality of life, satisfaction, physical health, psychological domain, and environmental domain in elderly individuals with dementia improved. However, there was no change in the social domain scores.
Conclusion : This study applied a traditional play applications to an elderly individual with dementia to examine its effects on cognitive function, depression, and quality of life. In the future, it is hoped that various comparative studies will be conducted by comparing existing applications and cognitive training for elderly individuals with dementia.
ANALISIS PENJATUHAN SANKSI PIDANA BAGI MASYARAKAT YANG MENOLAK VAKSINASI
Authors: Kusuma Aditama Candra , Fadillah Fachri Fadillah , Pratiwi Ni Wayan Widya
Published: January 2025

Infeksi virus Corona atau yang lebih dikenal dengan covid-19 masih sangat masif, hal tersebut membuat semua negara yang rakyatnya terjangkit virus ini menjadi lebih waspada dan mempersiapkan segala cara untuk melawan covid-19, salah satu cara yang ditempuh adalah vaksinasi. Vaksinasi merupakan salah satu terobosan mutakhir dalam dunia kesehatan karena bersifat preventif. Tujuan penelitian ini untuk mengetahui penegakan hukum terhadap masyarakat yang menolak vaksinasi serta untuk mengkaji sanksi ideal terhadap masyarakat yang menolak vaksinasi. Penelitian ini adalah penelitian hukum normatif. sifat penelitian ini adalah literer atau penelitian kepustakaan (library research). Hasil penelitian menunjukan bahwa Pasal 93 Undang- Undang Karantina Kesehatan bersifat Lex Specialis Sistematis sehingga dapat mengesampingkan Undang - Undang yang lainnya, maka sudah tepat penggunaannya sebagai upaya paksa pemerintah untuk kekebalan komunitas.
Kerjasama Internasional Dalam Pemberantasan Perdagangan Senjata Api Illegal di Kawasan Asia Tenggara
Authors: Usman Alifia Michelle , Putri Alvina Ahmadi , Nasution Fatihana Ulya , Ramadhan Muhammad Hafiz , Annisa Nurul
Published: January 2025

Istilah perdagangan gelap senjata api yang digunakan oleh Perserikatan Bangsa-Bangsa (PBB) adalah gerakan perdagangan senjata api secara ilegal yang dikendalikan oleh kelompok kriminal terorganisir. Gerakan tersebut khususnya terjadi di kawasan ASEAN dan bertentangan dengan hukum Nasional dan Internasional. Oleh karena itu, pertumbuhan perdagangan senjata api illegal akan meningkatkan kekhawatiran negara-negara Asia Tenggara. Penulisan ini bertujuan untuk mengkaji upaya kerjasama dalam pemberantasan perdagangan senjata api illegal di negara-negara ASEAN, serta tantangan dan hambatan dalam pelaksanaannya. Pendekatan kasus yang digunakan adalah pendekatan normatif dengan menggunakan metode penelitian statuta yang dikombinasikan dengan pendekatan komparasi kasus di negara-negara Asia Tenggara. Penelitian ini menunjukkan bahwa negara-negara ASEAN telah memanfaatkan sarana diplomatik yaitu ASEAN Regional Forum (ARF) dan pembentukan ASEAN Police (ASEANAPOL). Forum-forum tersebut diusulkan oleh ASEAN Political Security Community (APSC) dengan cara berkoordinasi dengan kepala polisi nasional negara-negara ASEAN yang meliputi, kebijakan penegakan hukum, pengadilan pidana dan kejahatan transnasional untuk memerangi perdagangan senjata api illegal di kawasan ASEAN. Namun, efektivitas APSC masih dipertanyakan karena perdagangan gelap senjata api belum bisa diberantas.
Perlindungan Hak Debitur Pinjaman Online (Pinjol) Dalam Perspektif Cyber Law
Authors: Rizka Rahadiyani Aisyah  , Nurul Bazroh  , Zahwa Rizqi Laurina  , Yosephine Fransisca  , Nazzari Azka
Published: January 2025

Perkembangan teknologi yang tidak terbatas di era digital sekarang ini, semakin lengkap dengan  hadirnya salah satu bentuk penerapan teknologi informasi di bidang keuangan, yaitu aplikasi  Pinjaman Online.Banyak orang berpikir bahwa Pinjaman Online ini adalah solusi yang mudah dan  cepat untuk mendapatkan uang. Perkembangan industri fintech ini juga lekat dengan stigma negatif  dari masyakarat khususnya dalam cara penagihan. Permasalahan Pinjaman Online atau Financial  Technology Peer To Peer Lending (Fintech P2P) kian hari terus menjadi sorotan publik. Berbagai  kasus pelanggaran Perusahaan Fintech mulai bermunculan di media massa. Bentuk pelanggaran oleh  Perusahaan Fintech ini juga beragam jenisnya. Mulai dari penagihan intimidatif (Pasal 368 KUHP dan  Pasal 29 jo 45 UU ITE), penyebaran data pribadi (Pasal 32 jo Pasal 48 UU ITE) penipuan (Pasal 378  KUHP). Sayangnya, penyelesaian hukum permasalahan ini masih minim sehingga kasus-kasus serupa terus bermunculan. Jurnal ini memuat tentang permasalahan hukum pada pinjaman online  illegal dan bentuk dari penyelesaian masalah pinjaman online yang marak saat ini. Tujuan jurnal ini  yaitu Untuk mengetahui penyelesaian masalah ancaman keamanan dan keselamatan yang dilakukan  kreditur terhadap debitur dalam kegiatan pinjaman online ilegal pada saat ini. Jurnal ini  Menggunakan metode penelitian Pendekatan undang-undang UU ITE. Hasil dari jurnal ini yaitu  Adanya legalitas perusahaan pinjaman online, maka pelanggaran hak pengguna layanan pinjaman  online diharapkan dapat meminimalkan resiko pelanggaran hak pengguna serta apabila pelanggaran  hak pengguna layanan tetap terjadi maka pihak yang berwenang dapat lebih mudah untuk  menjangkau pihak penyedia jasa layanan karena telah tersedianya dokumen yang lengkap tentang  pihak penyedia layanan tersebut.
IMPLEMENTASI PERPRES NO.13 TAHUN 2018 SEBAGAI STRATEGI PENCEGAHAN DAN PEMBERANTASAN TINDAK PIDANA PENCUCIAN UANG DI KORPORASI
Authors: Zhafirah Nisa Almira  , Keiza Aurora Karenina  , Thereza Hilya Hutasoit  , Hawila Winona Lakusa  , Dela Ulianda Simanjuntak
Published: January 2025

Indonesia sebagai salah satu negara berkembang yang sangat menitikberatkan perkembangan terhadap perekonomian kepada pihak swasta yang sekarang banyak di dominasi oleh pihak korporasi. Pada faktanya korporasi banyak yang melakukan tindak pidana pencucian uang agar asal usul harta kekayaan tersebut sulit dilacak oleh aparat penegak hukum dan masih banyak lagi faktor yang dapat menyebabkan terjadinya pencucian uang oleh korporasi. Maraknya tindak pidana pencucian uang dalam korporasi menjadi hal yang harus diatasi oleh pemerintah. Dimana kejadian tersebut perlu ditangani dengan strategi yang bisa berjalan efektif. Dengan hadirnya Perpres 13 tahun 2018 bisa menjadi upaya dalam mengatasi dan memberantas tindak pidana pencucian uang pada korporasi. Jenis penelitian yang digunakan yuridis normatif. Penelitian ini merupakan penelitian kepustakaan dengan pendekatan perundang-undangan dan konseptual. Diketahui terdapat beberapa problematika pada penanganan tindak pidana pencucian uang yang mengakibatkan dalam penerapannya belum bisa berjalan efektif. Hadirnya Perpres 13 tahun 2018 tentang tentang Penerapan Prinsip Mengenali Pemilik Manfaat dari Korporasi dalam Rangka Pencegahan dan Pemberantasan Tindak Pidana Pencucian Uang dan Tindak Pidana Pendanaan Terorisme. Dimana mengharuskan transparansi dalam penerapannya serta ditunjang dengan aturan teknis yang telah dikeluarkan yaitu Peraturan Kementerian Hukum dan Hak Asasi Manusia No. 15 tahun 2019 tentang Tata Cara Peraturan Pelaksanaan Penerapan Prinsip Mengenali Pemilik Manfaat Dari Korporasi dan Peraturan Kementrian Hukum dan Ham No. 21 tahun 2019 tentang Tata Cara Pengawasan Penerapan Prinsip Mengenali Pemilik Manfaat dari Korporasi. Maka penerapan Beneficial Ownership akan efektif, terukur, terkini, sehingga dapat mencegah dan memberantas TPPU pada korporasi.
Penegakan Hukum Tindak Pidana Illegal Fishing dengan Penenggelaman Kapal dalam Perspektif Pertahanan Nasional Indonesia
Authors: Kristanto Beny
Published: January 2025

Laut dan segala sumber dayanya merupakan bagian dari wilayah Indonesia yang harus dipertahankan dengan segala usaha demi untuk mempertahankan kedaulatan negara, keutuhan wilayah negara dan keselamatan segenap bangsa dari ancaman dan gangguan terhadap keutuhan bangsa dan negara. Pasal 33 ayat (3) UUD 1945 mengamanatkan bahwa bumi dan air dan kekayaan alam yang terkandung didalamnya dikuasai oleh negara dan dipergunakan untuk sebesar besarnya kemakmuran rakyat. Indonesia dengan luas lautan yang sedemikian luas ditambah dengan lokasi  yang strategis langsung berbatasan dengan negara negara lain sehingga seringkali terjadi pencurian perikanan yang dilakukan oleh nelayan negara tetangga (illegal fishing). Tindak pidana illegal fishing merupakan salah satu bentuk ancaman atau gangguan terhadap kedaulatan wilayah Indonesia sehingga terhadap pelaku tindak pidana illegal fishing harus tindakan yang tegas. Indonesia sebagai negara hukum maka tindakan tegas terhadap pelaku illegal fishing salah satunya dengan penegakan hukum. Penegakan hukum terhadap tindak pidana illegal fishing didasarkan pada UU RI Nomor 45 Tahun 2009 tentang Perubahan atas Undang Undang Nomor 31 Tahun 2004 tentang Perikanan dimana dalam undang-undang tersebut ada kewenangan pemusnahan benda dan/atau alat yang digunakan dalam dan/atau yang dihasilkan dari tindak pidana perikanan untuk menenggelamkan kapal perikanan yang berbendera asing. Penelitian ini menggunakan pendekatan yuridis empiris. Tulisan ini ingin melihat bagaimana proses penegakan hukum tindak pidana illegal fishing sampai dengan kegiatan  penenggelaman kapal terhadap kapal yang digunakan dalam tindak pidana illegal fishing dalam perspektif pertahanan nasional di wilayah perairan Indonesia. Penenggelaman kapal pelaku efektif sebagai upaya mempertahankan kedaulatan NKRI dengan pelaksanaan penenggelaman kapal dilakukan setelah mendapat putusan hakim melalui proses persidangan sehingga ada dasar yang kuat pemerintah melakukan  penenggelaman kapal.
Pemanfaatan Aset Debitur Pasca Kepailitan: Menuju Peningkatan Nilai Ekonomi dan Manfaat Bagi Kreditur
Authors: Siregar Mohammad Rizky
Published: January 2025

Penelitian ini menggunakan pendekatan kualitatif dengan desain deskriptif analitis untuk menganalisis mekanisme pemanfaatan aset debitur pasca kepailitan dalam hukum kepailitan di Indonesia. Tujuan utama penelitian ini adalah untuk mengidentifikasi strategi yang dapat meningkatkan nilai ekonomi dan manfaat bagi kreditur serta mengatasi tantangan dan hambatan dalam pemanfaatan aset debitur pasca kepailitan. Data dikumpulkan melalui observasi langsung terhadap pengelolaan aset oleh kurator dan pelaksanaan lelang, serta analisis data sekunder seperti dokumen hukum, literatur terkait, laporan pengadilan kepailitan, dan data statistik. Hasil penelitian diharapkan memberikan kontribusi signifikan dalam memahami dan mengatasi tantangan dalam pemanfaatan aset debitur pasca kepailitan di Indonesia, serta memberikan rekomendasi praktis bagi kreditur dan pihak-pihak terkait lainnya untuk meningkatkan efektivitas dan efisiensi dalam pemanfaatan aset debitur.
TRANSFORMASI HUKUM PERUSAHAAN: PENDEKATAN BARU MELALUI BLOCKCHAIN DALAM PENYELESAIAN KASUS KEPAILITAN DI INDONESIA
Authors: Selfeny Risca
Published: January 2025

Sistem hukum perusahaan di Indonesia saat ini masih mengandalkan proses manual dan tradisional dalam penyelesaian kasus kepailitan. Hal ini seringkali mengakibatkan proses yang berbelit-belit, tidak efisien, dan tidak transparan. Penelitian ini bertujuan untuk mengkaji potensi transformasi hukum perusahaan di Indonesia melalui penerapan teknologi blockchain dalam penyelesaian kasus kepailitan. Penelitian ini menggunakan metode penelitian hukum normatif dengan pendekatan yuridis-normatif. Data dikumpulkan melalui studi literatur dan peraturan perundang-undangan Penelitian ini menemukan bahwa teknologi blockchain memiliki potensi untuk mentransformasi hukum perusahaan di Indonesia dengan cara meningkatkan efisiensi dan transparansi dalam proses penyelesaian kasus kepailitan, Meningkatkan keamanan dan keandalan data terkait kasus kepailitan, dan Memfasilitasi kolaborasi dan komunikasi yang lebih baik antara berbagai pihak yang terlibat dalam proses penyelesaian kasus kepailitan. Penerapan teknologi blockchain dalam penyelesaian kasus kepailitan di Indonesia dapat memberikan manfaat yang signifikan bagi para pihak yang terlibat, termasuk debitur, kreditor, dan hakim. Oleh karena itu, perlu dilakukan kajian lebih lanjut dan upaya konkret untuk merealisasikan potensi transformasi hukum perusahaan ini.
Pobreza Menstrual: El impacto de la falta de recursos en la salud menstrual y la necesidad de apoyo legislativo y educación en América Latina
Authors: Mariantonella Picón  , Nicole Kozak
Published: January 2025

El Impacto de la Falta de Recursos en la Salud Menstrual y la Necesidad de Apoyo Legislativo y Educación en América Latina” aborda la problemática de la pobreza menstrual, que se refiere a la carencia de productos de higiene, educación adecuada y acceso a servicios sanitarios para la gestión de la menstruación. Este fenómeno afecta especialmente a adolescentes y jóvenes en América Latina, donde la pobreza y la falta de infraestructura agravan los riesgos para la salud menstrual, aumentando la probabilidad de infecciones y provocando un impacto emocional y psicológico debido al estigma social asociado a la menstruación. Las personas afectadas recurren a soluciones ineficaces, como el uso de materiales inadecuados, lo que compromete aún más su bienestar. El estudio subraya la urgencia de implementar políticas públicas que garanticen el acceso a productos de higiene menstrual, mejoren la infraestructura sanitaria y promuevan la equidad menstrual. Asimismo, destaca la necesidad de campañas educativas que eliminen el estigma y fomenten una comprensión adecuada de la salud menstrual. Este enfoque es clave para avanzar en los Objetivos de Desarrollo Sostenible (ODS) relacionados con la salud y el bienestar (ODS 3) y la igualdad de género (ODS 5).
Complicaciones, clínica y tratamiento de pacientes con hepatocarcinoma, posterior a quimioembolización en dos hospitales de Quito
Authors: Freire Ortiz Guadalupe Elizabeth , Briceño Kirby María Monserrate
Published: January 2025

INTRODUCCIÓN. La quimioembolización transarterial ha demostrado mejorar la tasa de sobrevida en los pacientes con hepatocarcinoma, se ha descrito como tratamiento paliativo; es útil, efectivo y bien tolerado. Esta terapéutica tiene el objetivo de disminuir el volumen tumoral. OBJETIVO. Determinar las complicaciones que presentan los pacientes con diagnóstico de hepatocarcinoma, posterior a la realización de quimioembolización transarterial del servicio de Gastroenterología del Hospital de Especialidades Carlos Andrade Marín y Hospital de Especialidades Eugenio Espejo, durante el período enero 2015 - enero 2020. MATERIALES Y MÉTODOS. Es un estudio observacional transversal; se diseñó un formulario de recolección de información, utilizando media y desvío estándar para variables cuantitativas; frecuencia y porcentaje para cualitativas; en las variables con distribución no paramétrico se recurrió a la mediana, rango intercuartil y sus intervalos, además se utilizó Chi Cuadrado, Índice de Yates y test de U Mann Whitney. Se trabajó en el paquete estadístico SPSS versión 26.  RESULTADOS. Se analizaron 97 pacientes, el 60,8% fue de sexo masculino con comorbilidad metabólica del 34%; la mayoría de los pacientes no tuvieron complicaciones, sin embargo, la hipertensión arterial se presentó como manifestación clínica post quimioembolización transarterial (10,3%); el choque, el síndrome ascítico – edematoso y el dolor abdominal fueron las complicaciones de mayor frecuencia. DISCUSIÓN.  La hipertensión arterial, el síndrome ascítico edematoso y el estado de shock fueron las complicaciones mayores más frecuentes; mientras que el dolor abdominal fue la complicación menor más prevalente. Estos hallazgos contrastan con una revisión sistemática ejecutada en Asia, en la que se evidenció que los efectos adversos más frecuentes de este procedimiento fueron el síndrome post quimioembolización, asociado a fiebre, náuseas, vómitos y de manera infrecuente cuadros como colecistitis, hepatitis isquémica, absceso hepático, tromboembolismo pulmonar, etc (Reig, Forner, Avila, Ayuso, & Minguez, 2021) (Bilbao, Páramo, Madrid, & Benito, 2018).  CONCLUSIÓN. Las complicaciones mayores se mantuvieron sobre la media general, y se tuvo una tasa de mortalidad esperada según la tendencia internacional.
Melatonin: Evolving Physiological Understanding and Potential Therapeutic Role in Pain Medicine Including Intervertebral Disc Degeneration
Authors: Shekoohi Sahar
Published: January 2025

BACKGROUND: Melatonin, one of the most versatile hormones in the body, is well appreciated in managing circadian rhythm and for antioxidant properties. Produced in the pineal gland and within mitochondria, melatonin influences many physiologic processes through receptor mediated and direct effects.

OBJECTIVE: The present investigation explores the evolving pharmacologic properties of melatonin, as well as current therapeutic uses in areas where mitigating oxidative stress, inflammation, and cellular senescence. This review also delves into novel therapeutic potential of melatonin and how current research is revealing a wide array of therapeutic promise in pain medicine.

STUDY DESIGN: A systematic review of randomized controlled trials (RCTs) and observational studies was performed using various search engines focused on melatonin and its role in pain medicine.

METHODS: The available literature on melatonin and pain medicine was reviewed. A comprehensive literature search of multiple databases from 1966 to July 2024, including manual searches of the bibliography of known review articles was performed. Quality assessment of the included studies and best evidence synthesis were incorporated into qualitative and quantitative evidence synthesis.

OUTCOME MEASURES: The primary outcome measure was the proportion of patients receiving melatonin with significant relief and functional improvement of greater than 50% of at least 3 months. Duration of relief was categorized as short-term (less than 6 months) and long-term (greater than 6 months).

RESULTS: Melatonin can affect intervertebral disc (IVD) health through the enhancement of survival and function of nucleus pulposus cells, primarily through activation of the ERK1/2 signaling pathway. Melatonin also influences the biochemical environment of the IVD by modulating inflammation and oxidative stress, crucial factors in the pathogenesis of disc degeneration. Melatonin has been shown to reduce senescence and promote autophagy within disc cells, vital for clearing out damaged cellular components, preserving cellular function and preventing deterioration associated with aging and degenerative diseases.

LIMITATIONS: Despite the availability of multiple studies, the paucity of clinical pain related literature is considered as the major drawback.

CONCLUSION: Based on the present systematic review, melatonin plays a critical role in sleep, but evolving studies have demonstrated substantive roles in mitigating degenerative conditions in various tissues, including IVD degeneration. Ongoing studies will better clarify the role of melatonin as a potential therapeutic agent, including the targeted delivery to various body regions.

KEY WORDS: Melatonin, 5-methoxy-N-acetyltryptamine, pineal gland, neurodegenerative disease, intervertebral disc disease
A Comprehensive Overview of the Stellate Ganglion Block Throughout the Past Three Decades: A Bibliometric Analysis
Authors: Kong Hao
Published: January 2025

BACKGROUND: Over the past 3 decades, clinicians and scholars have used and studied the stellate ganglion block (SGB) extensively, making this field a highly anticipated research hot spot. To the best of our knowledge, there has been no bibliometric analysis of the SGB until now.

OBJECTIVE: Our study aimed to complete multiple tasks regarding SGB research: identify the collaboration and impact of countries, institutions, journals, and authors, evaluate the knowledge base, trace the trends in hot spots, and explore the emerging topics relevant to the field.

STUDY DESIGN: A bibliometric analysis.

METHODS: Publications that were associated with the SGB and published between the years of 1993 and 2022 were retrieved from the Web of Science Core Collection on September 21st, 2023. CiteSpace 6.1.R6 and VOSviewer 1.6.18 were used to perform bibliometric and knowledge-map analyses.

RESULTS: This study found a total of 837 publications originating from 51 countries and 1006 institutions. These articles were published in 393 journals. The United States was the country that produced the most articles focused on SGB, and the University of California, Los Angeles was the institution associated with the greatest number of publications. The anesthesiology and cardiology journals surveyed for this study published the most articles and received the most citations. Among the authors whose works were examined, Kitajima T had the greatest number of published articles, and Lipov E was the most frequently cited co-author. Five main domains of SGB research included electrical storm and refractory ventricular arrhythmia, breast cancer and climacteric medicine, post-traumatic stress disorder, pain management, and cerebrovascular diseases. The latest hot topics involving this field focused on SGB’s anti-arrhythmic and anti-cerebral vasospasm effects and its treatment of long COVID syndrome.

LIMITATIONS: Data were retrieved only from the WoSCC; therefore, publications in other databases might have been missed.

CONCLUSION: This comprehensive bibliometric analysis conducted a complete overview of SGB research, which was helpful in furthering our understanding of research trends and locating research hot spots and gaps in this domain. This field is developing rapidly and will garner significant and continuous attention from future scholars.

KEY WORDS: Stellate ganglion block, bibliometric, knowledge-map, VOSviewer, CiteSpace, post-traumatic stress disorder, electrical storm, hot flashes
A Study to Assess the Effectiveness of Planned Teaching Programme on Knowledge Regarding Myocardial Infaraction and its Prevention among the Relatives of Patients Attending Diabetic Clinic at BVVS HSK Hospital and Research Centre, Bagalkot
Authors: D Mr. Prafull Kumar, , Gowda Dr. Yathi Kumar Swamy
Published: January 2025

Background of the study: Myocardial infarction is one of the most common complications associated with CEA. This is most likely related to the frequent concurrent occurrence of coronary and carotid atherosclerotic disease. The reported general incidence of perioperative myocardial infarction after CEA is approximately 1% to 4%.98 Operative stress from surgery in addition to perioperative hypertension, increased vascular volume, tachycardia, and the use of intraoperative barbiturates may be predisposing factors. Careful preoperative cardiac evaluation and strict attention to intraoperative and postoperative hemodynamic variables and cardiac monitoring help minimize perioperative cardiac morbidity. Aim: the aim of study was to assess the existing knowledge regarding Myocardial infarction and its prevention among the relatives of patients attending Diabetic clinic. Methodology: The research design selected for this study was pre-experimental one pre-test -post-test design. The sample size comprises of 30 relatives of patients attending Diabetic clinic at BVV sangha’s HSK Hospital and research centre, Bagalkot. The sampling technique adopted for this study will be convenient sampling technique. In the present study the data will be collected by using Structured closed ended Questionnaire, the data analysis done by using descriptive and inferential statistics in terms of frequency distribution, percentage, mean, mean percentage, Standard Deviation, paired ‘t’ test and Chi-square test. Result: The finding revealed In the area of knowledge on “Prevention”, pre-test mean knowledge score was 1.01 with SD ±3.23 which is 14% of total score where as post-test mean knowledge score was 3.01 with SD ±4.3 which is 61.4% of total score. The effectiveness of STP on Prevention, mean score was 2.37 with SD ±1.02 which is 47.4% of total score and As the calculated t value (24.17) was much higher than table ‘t’ value (2.045) the hypothesis: H1 -there is a significant difference ...
Masseter Hemangioma: A Case Report
Authors: Sarra Benwadih , Manal Anagam , Oumaima Boukhlouf , Dani Bouchra , Boulaadas Malik
Published: January 2025

Masseter hemangiomas are rare benign vascular tumors that arise from the proliferation of endothelial cells within the masseter muscle. While hemangiomas account for a significant proportion of vascular anomalies, intramuscular hemangiomas are exceedingly uncommon, particularly in the masseter region, which represents the most frequent site in the head and neck. Intense stretching of muscle fibers and associated nerves is believed to be a predisposing factor. This study aims to discuss the clinical presentation, diagnostic challenges, and management of masseter hemangiomas. We report a case of a patient diagnosed with a masseter hemangioma, treated successfully.
Prevalence and Pattern of Antimicrobial Resistance in ICU Patients with Sepsis in Dhaka City: A Single Center Study
Authors: Ashrafuzzaman Mohammad , Asaduzzaman Mohammod , Mondal Montosh Kumar , Jasham Md. Abdul Hamed , Tasnim Dr. Farhana , Polash Dr. Shahadat Hossain , Sultana Most. Nasrin
Published: January 2025

Background: Pathogenic resistance against antibiotics is substantially mounting in the developing countries including Bangladesh. Antimicrobial resistance is a rising concern specially among the critically ill patients who are often treated by multiple antibiotics. Objective: To observe the pattern of antimicrobial resistance among the patients diagnosed with sepsis admitted into the intensive care unit (ICU). Method: This observational study took place in the ICU of Bangabandhu Sheikh Mujib Medical University for 1 year. Samples of blood, urine, tracheal aspirate were obtained from 192 patients admitted in ICU with clinically diagnosed sepsis which were cultured and analyzed. Result: Mean age of the patients were 54.29 ± 19.443 years and 60.4% were males. The most common sample yielding positive culture was tracheal aspirate [94 (51.6%)]. Out of 530 samples, organisms were isolated from 158 samples. The most frequently isolated microorganisms were Klebsiella spp. 54 (35.29%), followed by Acinetobacter spp. 38 (24.83%), Pseudomonas spp. 19 (12.42%) and Candida spp. 15 (9.80%). Regarding antimicrobials, a range of drugs classified as Penicillins, Cephalosporins, Carbapenems, Fluroquinolones, Macrolides and others such as Trimethoprim/Sulfamethoxazole and Nitrofurantoin were found to be 100.0% resistant to Pseudomonas spp., Klebsiella spp., Acinetobacter spp. and E. coli. Conclusion: A high prevalence of resistance to most antibiotics was detected. Overall, such a revelation of increased antibiotic resistance demands for restrictive and appropriate antibiotic usage in accordance with the updated antibiotic prescribing policy in Bangladesh.