bluuebunny/crossref_metadata_2025 huggingface dataset:
Variability of alternating hemiplegia in children
Authors: Afanasyeva M. P. , Belousova E. D. , Sharkov A. A. , Gorchhanova Z. K.
Published: July 2024

Thе article describes two clinical cases of alternating hemiplegia (AH) in children of the same age group, but with different severity of clinical manifestations. The first patient, along with hemiplegic and epileptic seizures, demonstrates speech, behavioral and intellectual disorders, as well as motor disorders. The second patient, despite the presence of fairly frequent hemiplegic attacks, has no motor and intellectual disorders. The exact causes of such clinical variability are not yet known, which makes it difficult to predict the course in patients with AH.
Eklesiologi Intergenerasional
Authors: Hale Merensiana , Christiani Tabita Kartika , Epafras Leonard Chrysostomos
Published: July 2024

Abstract. The development of intergenerational ministry in the church requires a strong ecclesiological foundation. This article is a contribution of thought to the development of intergenerational services in the church, specifically the Evangelical Christian Church in Timor (GMIT). The purpose of this article focuses on offering the concept of ecclesiology as a basis for intergenerational services at GMIT. This concept was formulated based on a complementary discussion of the ideas of liquid ecclesiology by Pete Ward, ecclesiology from below by Roger Haight, the description of the Trinitarian church by Miroslav Volf with the metaphor of the familia Dei by GMIT. The result achieved is the concept of intergenerational ecclesiology which is characterized by several characteristics, namely: basic theology of the Church of God the Trinity, appreciative meaning of generational differences, has a transformative mission, moves dynamically and flexibly, and relations are heterarchical.Abstrak. Pengembangan pelayanan intergenerasional dalam gereja membutuhkan pendasaran eklesiologi yang kuat. Tulisan ini merupakan sumbangan pemikiran bagi pengembangan pelayanan intergenerasional dalam gereja, secara khusus pada Gereja Masehi Injili di Timor (GMIT). Tujuan tulisan ini berfokus pada tawaran konsep eklesiologi sebagai dasar pelayananan intergenerasioanal di GMIT. Konsep ini dirumuskan berdasarkan sebuah percakapan komplementer gagasan eklesiologi cair oleh Pete Ward, eklesiologi dari bawah oleh Roger Haight, gambaran gereja Trinitarian oleh Miroslav Volf, dengan metafora familia Dei oleh GMIT. Hasil yang dicapai adalah konsep eklesiologi intergenerasional yang dicirikan dengan beberapa karakteristik, yakni: dasar teologi gereja Allah Trinitas, pemaknaan apresiatif terhadap perbedaan generasi, memiliki misi transformatif, bergerak secara dinamis dan fleksibel, dan relasi bersifat heterarkis.
Evaluasi Konsep Missio Dei dalam Pemikiran Lesslie Newbigin
Authors: Harianja Doni Herwanto
Published: July 2024

Abstract. This article aimed to review the concept of missio Dei in the thought of Lesslie Newbigin, as well as to examine the criticisms and evaluations directed towards him. At first glance, Newbigin's concept of missio Dei emphasizes centrifugal movement rather than to centripetal movement within the church. In this regard, utilizing the missio Dei framework proposed by Stefan Paas, the author conducted a reexamination of Newbigin's thought and evaluates the criticisms directed towards it. This study demonstrated that in Newbigin's conceptualization, which tends to emphasize centrifugal aspects, also contains centripetal aspects within it.Abstrak. Artikel ini bertujuan untuk mengulas kembali konsep missio Dei dalam pemikiran Lesslie Newbigin, serta meninjau kritikan maupun evaluasi yang ditujukan kepadanya. Sekilas dalam konsep missio Dei Newbigin sangat menekankan gerakan sentrifugal dibandingkankan gerakan sentripetal di dalam gereja. Dalam hal ini, dengan menggunakan kerangka pemikiran missio Dei dari Stefan Paas, penulis melakukan penyelidikan kembali terhadap pemikiran Newbigin, dan mengevaluasi kritikan yang ditujukan kepadanya. Penelitian ini menunjukkan bahwa konsep pemikiran Newbigin yang cenderung menekankan aspek sentrifugal, di dalamnya juga terkandung aspek sentripetal.
¿Una ética para la IA? Mesa redonda sobre ética y autoría en el +RAIN Film Festival 2023
Authors: Sánchez Manzano Miriam
Published: July 2024

En el marco de la primera edición del +RAIN Film Festival, el primer festival europeo de películas generadas con Inteligencia Artificial, Sara Suárez-Gonzalo, Albert Sabater, Claudia Giannetti y Patrícia Ventura participan en una mesa redonda centrada en el papel de la ética y la autoría en los procesos de creación audiovisual y artística en la era de la IA generativa. Este artículo sirve de introducción a las aportaciones que se llevaron a cabo durante la sesión, ofreciendo una puerta de entrada para explorar el complejo escenario ético que plantea la IA. Aunque las discusiones actuales parecen precursoras en este ámbito, en realidad, desde la aparición de los modelos de aprendizaje computacional, hay una pregunta que persiste: ¿a quién debemos aplicar los principios éticos cuando hablamos de limitar el uso de la IA, a los humanos o a las máquinas?
Rational causal induction from events in time
Authors: Gong Tianwei , Pacer M , Griffiths Tom , Bramley Neil R
Published: July 2024

A longstanding focus in the causal learning literature has been on inferring causal relations from contingency data, which abstracts away from time by collating independent instances or aggregating over regularly demarcated trials. In contrast, individual causal learners encounter events in their daily lives that occur in a continuous temporal flow without distinct experimental trials. Consequently, the process of learning causal relationships in naturalistic environments remains comparatively less understood. In this paper, we develop a rational framework that foregrounds the role of time in causal learning. We work within the Bayesian rational analysis tradition, linking causal influence with dependence between events in continuous time via stochastic processes from the Poisson--Gamma distribution family. We demonstrate the qualitative differences in temporal patterns when two variables are related vs. unrelated, and the quantitative steps needed to infer causal structure from temporal patterns. We show that our rational account parsimoniously explains the human preference for causal explanations that involve shorter, more reliable and more predictable causal influences. Furthermore, we show this provides a unifying explanation for human judgments across seven experimental datasets from the causal learning literature.
Development and validation of the Spanish Process-Based Assessment Tool (PBAT)
Authors: Goicoechea Carmen , Wallman-Jones Amie , Ciarrochi Joseph , Hayes Steven C. , Hofmann Stefan G. , Perakakis Pandelis
Published: July 2024

The Process-Based Assessment Tool (PBAT) was developed to monitor biopsychosocial processes of change that are of relevance to individual treatment goals. It applies an idionomic approach to identify key processes of change, using high temporal density measurement applied at the level of the person. The purpose of the present study was to psychometrically validate the Spanish version of the PBAT and to expand the cross-cultural application of the questionnaire. A representative sample of 602 participants completed an online, cross-sectional questionnaire. Methods from the original study were followed including the same criterion variables; psychological distress (sadness, anxiety, stress, anger, lack of social support), health, and vitality level, and the need or frustration of autonomy, connection, and competence. Results showed that PBAT items significantly predicted criterion variables; Positive behaviors from the PBAT were the strongest predictors of health, vitality, as well as need satisfaction of autonomy, connection and competence. Negative behaviors from the PBAT were the strongest predictors of psychological distress, as well as the frustration of autonomy, connection and competence. Despite evidence for cultural differences in specific items, the overall conclusions of this validation study are consistent with the original study. The Spanish version of PBAT can be recommended for use in further scientific research and therapeutic processes.
Denial and Misinformation in Defense of the Tar Sands: The Case of a Canadian Think Tank
Authors: Haney Timothy
Published: July 2024

Literatures within the sociology of science and environmental sociology often focus on climate change denial, misinformation, and the role of think tanks in fuelling public skepticism. This work draws our attention to the arguments these organizations make and how they communicate doubt to the public. Less often have they focused on the ways that particular, locally emplaced organizations defend the material interests of the fossil fuel industry. This paper draws upon existing literature to perform a discourse analysis of the public communication (newsletters, press releases, website, blog, YouTube videos, and social media posts) of a Canadian think tank called Friends of Science based in Calgary, Alberta—the economic hub of Canada's tar sands. Through the analysis, I show how this organization works to cast doubt on anthropogenic climate change, communicates this doubt to the public, and slips from communicating about scientific matters—their stated goal—into matters of social, economic, and political advocacy. I show how this is done instrumentally in ways that protect the economic and social interests of Alberta’s oil industry.
Unlinking Linked Fate: The Push and Pull Factors of Group Consciousness
Authors: Kim Jae Yeon , Cho Joan , Kim DG , Lee Taeku
Published: July 2024

Scholars have long debated the association between the marginalized status of Asian Americans and their group consciousness. In this paper, we propose that the perceived discrimination effect depends on situational cues, which we define as push and pull factors. Based on a pre-registered survey experiment on Asian Americans ($n$ = 2,000), we find that the effect of perceived discrimination on Asian American solidarity is conditional. Priming anti-Asian hate crimes "pushes" up Asian Americans’ expressed linked fate. This boost, however, is "pulled" back down when the hate crime news story is combined with exposure to an FBI report on threats from China. When the hate crime news story is combined with a message on Asian American political under-representation, we find no additional boost to Asian Americans' linked fate orientation. In additional analyses of open-ended responses, 49\% of respondents believed that Asian Americans would fail to unite due to their internal diversity, lack of political agency, and lack of outside support. We conclude that perceived marginalization can enhance group consciousness but with important constraints. Specifically, the effect can be short-lived when Asian Americans are reminded of their precarity to state-sanctioned ethnic targeting.
Analisis Pengaruh Daya Tarik Beauty Influencer Dan Kepercayaan Terhadap Niat Beli Melalui Hubungan Parasosial Pada Kosmetika Somethinc
Authors: Septiara Dwi Putri , Iriani Sri Setyo , Artanti Yessy
Published: July 2024

Riset ini bertujuan untuk menguji dampak daya tarik beauty influencer dan kepercayaan terhadap niat beli produk kosmetika Somethinc melalui hubungan parasosial. Hubungan parasosial mengacu pada interaksi yang terbentuk antara konsumen dan influencer di media sosial. Riset ini menggunakan pendekatan kuantitatif dengan teknik pengumpulan data berupa kuesioner online yang disebar kepada responden yang mengenal Somethinc serta Tasya Farasya. Riset ini mengidentifikasi dan menganalisis faktor-faktor yang mempengaruhi niat beli calon konsumen, khususnya dalam kosmetika Somethinc. Variabel independen dalam riset ini adalah daya tarik beauty influencer Tasya Farasya dan kepercayaan brand, variabel dependen adalah niat beli, dan variabel intervening adalah hubungan parasosial. Data dianalisis menggunakan teknik analisis Structural Equation Modelling (SEM) berbasis Partial Least Square (PLS).
Realidad aumentada: tecnología emergente para la formación empresarial
Authors: Murcia Rodríguez Jennifer , López Martínez Sergio Andrés
Published: July 2024

Introducción: El emprendimiento es un eje importante en el mundo empresarial que permite que las personas desarrollen unidades productivas de manera independiente, sin estar vinculadas a una empresa como empleados. Constituye un reto, pues supone asumir responsabilidades comerciales para lograr incursionar en un mercado objetivo. Existen capacitaciones en competencias empresariales y, entre estas, la Realidad Aumentada (RA) se convierte en una tencología interactiva que favorece un aprendizaje significativo para recordar lo aprendido y para poner en práctica los conocimientos en emprendimiento. Metodología: tiene un enfoque cuantitativo de tipo descriptivo para conocer percepciones y experiencias de docentes universitarios sobre la RA en la formación empresarial. Resultados: Es un hallazgo que la RA se conoce como una tecnología emergente para entretenimiento, pero no para los procesos de formación empresarial. Discusión y conclusiones: aunque el mundo está en pleno desarrollo de la cuarta revolución industrial, la RA no es abordada en todas sus posibilidades en los diversos contextos sociales, como por ejemplo el educativo, por lo que es importante potenciar la RA para formar a los ciudadanos interesados en promover unidades productivas de manera independiente.
Uloga obiteljskih i školskih čimbenika u razvoju problematične uporabe interneta i problema mentalnog zdravlja
Authors: Stanić Luka
Published: July 2024

Cilj je istraživanja bio ispitati ulogu majčine psihološke kontrole i nezadovoljenja psiholoških potreba u školskome okruženju u razvoju problema mentalnoga zdravlja i problematične uporabe interneta. U istraživanju su sudjelovala 342 adolescenta iz triju zagrebačkih srednjih strukovnih škola (Mdob = 16.45, SD = 0.533), od čega 174 mladića. U istraživanju su ispitani percipirana majčina psihološka kontrola, nezadovoljenje potrebe za autonomijom i kompetentnošću u školskome okruženju, simptomi depresivnosti, anksioznosti i stresa te problematična uporaba interneta. Rezultati pokazuju da djevojke iskazuju više razine problematične uporabe interneta i problema mentalnoga zdravlja nego mladići. Analizom traga utvrđen je izravan učinak majčine psihološke kontrole na nezadovoljenje potreba te na internalizirane probleme. Rezultati pokazuju da je nezadovoljenje potreba medijator između psihološke kontrole, internaliziranih problema te problematične uporabe interneta. Također, stres je medijator između psihološke kontrole i problematične uporabe interneta, ali samo kod djevojaka. Istraživanje doprinosi razumijevanju problematične uporabe interneta među adolescentima u Hrvatskoj. Preciznije, istraživanje potvrđuje teorijske pretpostavke teorije samoodređenja da se negativni učinci psihološke kontrole povezane s uspjehom mogu odraziti na druge kontekste, poput školskoga okruženja, i dovesti do nezadovoljenja potreba u tome okruženju. To naposljetku može dovesti do negativnih posljedica za dobrobit adolescenata u obliku problema s mentalnim zdravljem i problematične uporabe interneta. Rezultati istraživanja mogu poslužiti pri kreiranju intervencija za poboljšanje školskoga okruženja te za usvajanje strategija suočavanja s nezadovoljenjem psiholoških potreba da bi se spriječili problematična uporaba interneta i internalizirani problemi.
Paleoproterozoic Dacite Dykes of the Vorontsovka Terrane, Volga-Don Orogen: Geochemistry, Age and Petrogenesis
Authors: Savko Konstantin A. , Samsonov Aleksandr V. , Korish E. H. , Bazikov Nikolay S. , Larionov Aleksandr N.
Published: July 2024

The metamorphosed dacitic porphyry dykes were established for the first time in the western part of the Vorontsovska terrane, which is located in the Paleoproterozoic Volga-Don orogen at the margin of Archean Sarmatia and Volga-Ural cratons. The magmatic protolith age for the metadacites is ca. 2.07 Ga. They are ferrous, metaluminous rocks of calc-alkali series and belong to I-type granitoids. Sodium specialization, low concentrations of Mg, Cr, Ni, incoherent elements with sufficient REE fractioning and absence of Eu*-anomalies, high Sr/Y ratio and especially (Gd/Yb)n values (10), and also radiogenic Nd isotopic composition suppose the juvenile mafic source for the dacitic melts. According to petrogenetic estimations, such conditions could be caused by partial melting of depleted N-MORB type basites at the equilibrium with the eclogitic restite. Supposed mechanism for the dacitic magmas forming is the partial melting of the basites from the lower horizons of crust with highly enlarged thicknes (60 km) due to preceding collision processes.
City Through the Eyes Of Students' Youth: Assessment and Regional Practices (A Case Study of Nizhny Novgorod)
Authors: Chepyuk O. R. , Angelova O. Yu. , Makarova S. D. , Bryandinskaya N. G. , Petrova O. V.
Published: July 2024

Russian universities at the present stage play a significant role in shaping the students professional preferences and migration expectations, thereby contributing to socio-economic development and influencing the process of human capital management at the regional level. The issue of immersing a university in the problems of a city (region) becomes especially relevant in light of global challenges, such as demographic changes, economic instability, and a lack of qualified personnel. One of the important areas of research is the analysis of how students evaluate the city of study, which may become their future place of residence and professional activity. The publication presents the results of such a study – a long-term survey of young people (students of the largest Nizhny Novgorod university – Lobachevsky University) about the conditions for their professional growth and development in one of the largest Russian cities – Nizhny Novgorod. The survey period (2017-2023) covered not only significant events related to the implementation of large infrastructure projects in the city (2018 FIFA World Cup, the 800th anniversary of Nizhny Novgorod in 2021, recognition of the city as New Year’s (2022) and Youth (2023) capitals of Russia), but also during the COVID-19 pandemic. One of the areas of the research that determined its novelty was the assessment of the city as a center for the development of creative industries, as well as a structural analysis of the results when dividing respondents by type of planned career trajectories. The discussion compared the results with similar studies from other regions of Russia. The results of the study are of interest for university management and regional policy, emphasizing the importance of the interaction of educational institutions with the urban environment in the context of the preservation and development of human resources in the region.
Engineering Activity and Engineering Thinking in the Context of Artificial Intelligence Expansion
Authors: Sheinbaum V. S. , Nikolskiy V. S.
Published: July 2024

The academic press is increasingly discussing the impact of Artificial Intelligence (AI) technologies on education and science. Researchers pay attention not only to the applied aspects of the use of AI technologies, but also to the issues of the ontological foundations of activity that are being transformed under the influence of new technologies. However, the issues of the impact of AI technologies on engineering activity, engineering thinking and, consequently, on engineering education are not sufficiently reflected in academic publications. Moreover, the aspects related to the widespread use of artificial intelligence, both in professional activities and in everyday life, remain insufficiently studied.

The article proposes theses and corresponding arguments that clarify the fundamental changes occurring in engineering activity and engineering thinking in the context of the expansion of artificial intelligence technologies. Engineering activity is presented as a system that is not identical to the activity of individual engineers. A definition of engineering activity is proposed, which reveals its essence through its goal of solving human and societal problems. A non-instrumental approach to the interpretation of engineering based on AI technologies is substantiated, within which artificial intelligence appears as a partner in engineering activity. Finally, engineering thinking is complemented by anticipatory and responsible thinking.

The article is a contribution to the academic discussion on the specifics of engineering activity and engineering thinking at the present stage.
Kedudukan Peraturan Pemerintah Pengganti Undang-Undang di Tinjau Dari Hierarki Perundang-Undangan Indonesia
Authors: Hanum Roro Hanum , Murdiana Elfa , Bahari Raha
Published: July 2024

Abstrak : In the context of law and regulations in Indonesia, the concept of hierarchy is vital for ensuring control over regulations that could potentially harm society both materially and non-materially. This concept is rooted in Hans Kelsen's theory of legal norms, which posits that legal norms have hierarchical levels, with grundnorms at the top. These norms are interrelated and form a coherent legal order. However, the application of this hierarchy is influenced by political factors that shape the constitutional system.One significant legal instrument reflecting this hierarchy in Indonesia is the Government Regulation in Lieu of Law (Perppu), which holds an equivalent position to regular laws in the Indonesian presidential system. It is essential to clearly define the term "compelling urgency" as the basis for issuing a Perppu to ensure that the President's actions remain within objective limits. Understanding and reviewing this legal hierarchy is crucial for maintaining the quality and enforcement of regulations in Indonesia. In this framework, legal comprehension revolves around official laws, and all aspects of law, norms, rules, and legal actions must align with the applicable laws. The evolution of legislation impacts various aspects of society, and a precise understanding of hierarchy and the concept of judicial review is indispensable for upholding the quality of law and justice in Indonesia.
Design and Implementation of Hamming Code with Error Correction Using Xilinx
Authors: Ms. Delphine Mary. P  , Simran. A
Published: July 2024

Advanced electrical circuits are very concerned about error-free communication. Information mistakes that happen during transmission may result in incorrect information being received. Error correction codes are frequently employed in electrical circuits to safeguard the data stored in memory and registers. One of these forward error correcting codes is the hamming code. It either employs the even parity or odd parity check approach. Here, we used the even parity check approach to implement hamming code. Compared to the parity check approach, hamming code is better. The hamming code is implemented here in Xilinx and uses a 7-bit data transmission scheme with 4 redundant bits. It is also used in the DSCH (Digital Schematic Editor & Simulator) programme. To find double bit errors, a specific parity bit is employed. For error detection and correction in this instance, we employed the SEDC-DED (Single Bit Error Detection and Correction-Double Bit Error Detection) method.
Perfil de Mortalidade e Análise Espacial de Neoplasias em um Município do Interior Paulista no Biênio 2019-2020
Authors: Moreira João Paulo , Rosa Ana Priscila Eleodoro , Souza João Paulo , Santos Luciane Loures dos
Published: July 2024

Introdução: O câncer é uma das principais causas de óbito em todo mundo. Diferenças socioeconômicas e ambientais refletem nas taxas de mortalidade entre diferentes Regiões. Objetivo: Caracterizar e descrever o perfil da população que foi a óbito por neoplasias em Ribeirão Preto/SP, segundo sexo, raça/cor, faixa etária e local de residência (2019-2020) e estabelecer uma relação com óbitos por covid-19 em 2020. Método: Estudo transversal, observacional, com análise de dados de declarações de óbito por algum tipo de neoplasia como causa básica e cálculos de frequências absolutas e relativas do perfil populacional de óbitos, coeficientes de mortalidade, e agrupamentos por sistemas, segundo a CID-10. Identificaram-se os óbitos com características econômicas das Regiões do município, e os mapas com as principais causas foram elaborados, relacionando-os com a condição econômica, segundo dados do IBGE, além da taxa padronizada de mortalidade. Resultados: Ocorreram 1.766 óbitos, com predomínio da faixa etária de 61-80 anos (52,8%). Houve crescimento de 19,4% em 2020. As neoplasias mais prevalentes foram no sistema digestivo (33,7%), porém o pulmão foi o órgão mais acometido (14,4%). Do total, 8,9% dos óbitos estiveram associados à infecção pela covid-19. O Centro apresentou maior coeficiente de mortalidade (2,5/mil habitantes), contudo a Zona Norte mostrou maior taxa padronizada de mortalidade (27,9/mil habitantes). O estudo sugere que houve distribuição heterogênea pelo município, com vulnerabilidades como renda, que contribuiu com o desfecho analisado. Conclusão: É importante considerar a disparidade socioeconômica-espacial de Ribeirão Preto na criação e aplicação de programas de prevenção, rastreio e tratamento de neoplasias na população.
Acerca de las funciones psicológicas: un post-scriptum
Authors: Ribes-Iñesta Emilio ,   Universidad de Guadalajara
Published: July 2024

Se describen los cuatro factores que caracterizan una función estímulo-respuesta: la mediación, el tipo de relación, el desligamiento funcional de la respuesta, y el criterio de ajuste. Se examina su correspondencia con las cuatro formas de causalidad aristotélica: material, formal, eficiente y final.
Method Gemi Self Assessment Untuk Identifikasi Management Lingkungan Rumah Pemotongan Unggas Di Pasar Tambahrejo Surabaya
Authors: Pandriratri Purnasari , Rachmanto Tuhu Agung , Purnomo Yayok Suryo , Cahyonugroho Okik Hendriyanto
Published: July 2024

Pasar Tambahrejo merupakan salah satu pasar tradisional kota Surabaya yang memiliki usaha pemotongan ayam yang sudah memenuhi syarat dan ketentuan, sehingga usaha pemotongan ayam tersebut sudah mendapat izin resmi pendirian dari pemkot Surabaya. Namun, dalam setiap proses produksi pasti menghasilkan limbah yang mempengaruhi pencemaran lingkungan. Masalah pencemaran lingkungan selalu mempunyai dampak yang harus diperhatikan bagi perusahaan. Disisi lain juga dapat menyebabkan munculnya berbagai penyakit jika pengolahannya tidak diperhatikan. Oleh karena itu, diperlukan perencanaan untuk melaksanakan ISO 14001:2015 guna menunjang perkembangan perusahaan. Pada penelitian ini menggunakan checklist GEMI (Global Environmental Management Initiative) dan metode GAP analysis, kemudian didapatkan hasil persentase 5 klausul yaitu kepemimpinan sebesar 50%, perencanaan 47%, operasional 42%,  evaluasi performa 39%, dan perbaikan berkelanjutan 50%.
Sosialisasi Pentingnya Tracer sebagai Kartu Pelacak Berkas Rekam Medis Keluar dari Rak Penyimpanan
Authors: Sulisna Aida , Meliala Sri Agustina
Published: July 2024

Tracer rekam medis merupakan sarana yang dimanfaatkan guna mengontrol penggunaan rekam medis. Biasanya digunakan untuk menggantikan dokumen rekam medis yang keluar dari rak penyimpanan. Dalam rekam medis yang lengkap dan benar dapat diperoleh informasi yang dapat digunakan untuk berbagai keperluan tersebut antara lain untuk bahan bukti di pengadilan, pendidikan dan pelatihan serta dapat digunakan untuk bahan analisis dan evaluasi mutu pelayanan rumah sakit. Mengingat kegunaan rekam medis yang banyak maka diperlukan pengendalian terhadap pengisian formulir rekam medis. Filling dalam bidang rekam medis adalah suatu ruangan yang bertanggung jawab terhadap penyimpanan, retensi dan pemusnahan dokumen rekam medis. Selain itu filling juga menyediakan dokumen rekam medis yang telah lengkap isinya sehingga dapat memudahkan penggunaan mencari informasi sewaktu-waktu jika diperlukan. Pentingnya Tracer sebagai kartu pelacak berkas rekam medis keluar dari rak penyimpanan berkas rekam medis sangat pelu untuk disosialisasikan kepada masyarakat tenaga kesehatan dalam hal ini Klinik Pratama Klambir. Tujuan dari kegiatan ini adalah memberikan pengetahuan tentang pentingnya tracer sebagai kartu pelacak berkas rekam medis keluar dari rak penyimpanan di Klinik Pratama Klambir. Kegiatan ini diharapkan dapat menciptakan budaya pemanfaatan tracer sebagai kartu pelacak berkas rekam medis ketika keluar dari rak penyimpanan dikarenakan tracer rekam medis begitu penting sebagai kartu pelacak ketika berkas keluar dari rak penyimpanan. Dengan begitu, berkas rekam medis akan dengan mudah ditemukan kembali saat dibutuhkan. Metode yang digunakan dalam kegiatan ini yaitu sosialisasi dengan memberikan penyuluhan berupa ceramah dan tanya jawab mengenai pentingnya tracer rekam medis.
Sirkumsisi di Masa Pandemi COVID-19 dengan Protokol Kesehatan di Klinik Ratih Herbalis Paya Mabar
Authors: Mulidan Mulidan , Muflih Muflih
Published: July 2024

Sirkumsisi adalah tindakan operatif yang ditujukan untuk mengangkat sebagian maupun seluruh bagian dari kulup atau prepusium dari penis. Sirkumsisi termasuk dalam prosedur bedah minor. Prosedur ini merupakan yang paling umum dilakukan di dunia. Di Indonesia sirkumsisi lebih dikenal dengan istilah khitan atau masyarakat sering menyebutnya sunat. Dalam masa pandemi COVID-19 banyak masyarakat yang takut datang ke fasilitas kesehatan untuk melaksanakan khitan dan mendapatkan pengobatan, oleh sebab itu dilaksanakan sirkumsisi dengan menerapkan protokol kesehatan. Pengabdian masyarakat ini merupakan bakti sosial dengan melakukan sirkumsisi secara gratis kepada masyarakat di lingkungan Klinik Ratih Herbalis Paya Mabar. Tujuan dari pelaksanaan kegiatan ini adalah memberikan pelayanan kesehatan berupa sirkumsisi kepada masyarakat yang membutuhkan yang sudah mendaftar sebelumnya kepada panitia pelaksanaan melalui promosi kesehatan yang dilakukan di Klinik Ratih Herbalis Paya Mabar. Pengabdian masyarakat ini dilakukan di Klinik Ratih Herbalis Paya Mabar Kec. Stabat, Kabupaten Langkat pada tanggal 25 Desember 2021 pukul 08.00-12.00 WIB yang diikuti oleh peserta sirkumsisi sebanyak 96 pasien. Metode yang digunakan dalam kegiatan ini yaitu pelaksanaan sirkumsisi langsung kepada pasien yaitu anak laki-laki yang berumur 7-12 tahun. Petugas kesehatan yang melaksanakan kegiatan ini sebanyak 2 orang dokter, 10 perawat dan dibantu oleh beberapa mahasiswa D3 Keperawatan Institut Kesehatan Helvetia. Kesimpulan dari pengabdian masyarakat ini yaitu telah di lakukan sirkumsisi dengan baik dan lancar.
Bioteknologi Kombucha Bunga Telang (Clitoria ternatea L) dengan Variasi Gula Stevia sebagai Antikolesterol pada Bebek Pedaging
Authors: Rezaldi Firman , Setiawan Usman , Kusumiyati Kusumiyati , Trisnawati Desi , Fadillah M. Fariz , Setyaji Diyan Yunanto
Published: July 2024

Pendahuluan: Hiperkolesteromia merupakan salah satu penyakit yang dapat menyebabkan berbagai komplikasi kesehatan manusia. Faktor pemicu terjadinya kadar kolesterol tinggi bisa berupa rutinnya dalam mengkonsumsi protein hewani, salah satu sumber protein hewani adalah daging bebek. Tujuan: Untuk menghasilkan daging bebek yang rendah kolesterol. Penelitian ini menggunakan bebek pedaging sebanyak 20 ekor dengan usia 3 bulan yang diberi perlakuan kombucha bunga telang pada konsentrasi gula stevia yang berbeda-beda sebagai substratnya yang telah difermentasi selama 2 minggu pada suhu 26oC. Metode: Secara Rancangan Acak Lengkap (RAL) dengan 4 perlakuan selama 1 bulan. Pengulangan pada setiap perlakuan dilakukan sebanyak 5 kali. Komposisi perlakuan adalah sebagai berikut: P0 yaitu kontrol tanpa mengandung kombucha bunga telang dengan substrat gula stevia. P1, P2, dan P3 yaitu air minum yang mengandung fermentasi kombucha bunga telang dengan konsentrasi gula stevia masing-masing sebesar 20%, 30%, dan 40%. Parameter yang diukur dalam penelitian ini diantaranya adalah kadar kolesterol, bobot tubuh, dan konsumsi air minum. Data yang dihasilkan dianalisis menggunakan ANOVA serta dilanjutkan dengan uji Duncan pada taraf kepercayaan 95%. Hasil: Menunjukkan bahwa pemberian kombucha bunga telang dengan substrat gula stevia berpotensi dalam menurunkan kadar kolesterol pada bebek pedaging secara nyata. Kesimpulan: Konsentrasi gula stevia sebesar 40% pada fermentasi kombucha bunga telang merupakan konsentrasi terbaik dalam menurunkan kadar kolesterol, menurunkan bobot tubuh, dan air minum.
Pengaruh Pengolahan Buah Salak Pondoh (Salacca zalacca (Gaertn.) Voss) terhadap Kadar Vitamin C
Authors: Pujiono Fery Eko , Mulyati Tri Ana
Published: July 2024

Pendahuluan: Salak banyak diproduksi karena peningkatan jumlah konsumsi buah salak disetiap tahunnya. Hal ini dikarenakan salak memiliki kandungan gizi yang sangat tinggi. Kandungan karbohidrat dan air yang sangat tinggi ini menyebabkan salak lebih mudah busuk sehingga umumnya buah salak hanya dapat bertahan selama 7 hari pada suhu kamar. Disisi lain, Perubahan lain yang cukup merugikan adalah terjadinya perubahan warna daging buah secara 2 enzimatis karena kandungan tanin yang memberikan rasa sepat pada salak jika terkena udara maka akan menghasilkan perubahan warna coklat (reaksi browning enzymatic). Produk hasil pengolahan salak termasuk jus, selai, dodol, asinan, dan manisan salak. Namun, permasalahan yang terjadi adalah pengolahan buah ini dapat mempengaruhi kadar gizi terutama vitamin C. Hilangnya vitamin C selama proses pengolahan buah dapat terjadi karena proses oksidasi akibat pemanasan atau aktivitas enzimatik Tujuan: Mengetahui pengaruh pengolahan buah salak terhadap kadar vitamin C. Metode: Penelitian ini menggunakan UV-Vis untuk penentuan kadar Vitamin C sebelum dan sesudah diolah menjadi manisan salak. Pengolahan manisan salak dilakukan pada berbagai waktu yaitu 5 menit (Manisan A), 10 menit (Manisan B), 20 menit (Manisan C) dan 30 menit (Manisan D). Instrumen yang digunakan untuk mengukur kadar vitamin C adalah UV-Vis dan panjang gelombang maksimum yang digunakan adalah 265 nm. Hasil: Berdasarkan hasil penelitian dapat disimpulkan bahwa pengolahan salak pondoh menjadi manisan salak pondoh basah dapat menurunkan kadar vitamin C. Semakin lama waktu pengolahan salak pondoh maka kadar vitamin C semakin menurun. Kadar vitamin C tertinggi terdapat pada sampel buah salak pondoh segar (kontrol) yaitu 4,913 ± 0,076 mg/100 g. Adapun kadar vitamin C terendah terdapat pada sampel Manisa D (pengolahan 30 menit) yaitu 0,363 ± 0,031 mg/100 g. Simpulan: Semakin lama waktu pengolahan salak pondoh maka kadar vitamin C semakin menurun
Pengaruh Terapi Edukasi Gizi Encorage and Motivate (EncoMo) terhadap Penurunan Berat Badan Siswa Obesitas di SMPN 164 Jakarta
Authors: Said Irfan , Manggabarani Saskiyanto , Lestari Dwi Ayu , Tanuwijaya Rani Rahmasari , Barokah Falah Indriawati
Published: July 2024

Obesitas merupakan masalah kesehatan masyarakat yang utama, terutama pada anak usia sekolah. Menurut data WHO 2016, sekitar 650 juta orang mengalami obesitas dan pada usia 5-19 dan 340 juta mengalami kelebihan berat badan pada usia 5-19 tahun. Orang yang mengalami obesitas di masa kanak-kanak memiliki risiko lebih tinggi untuk menjadi gemuk di masa dewasa. Obesitas pada anak dapat meningkatkan risiko kematian dini dan kecacatan di masa dewasa. Tujuan khusus dari penelitian ini adalah untuk mengevaluasi pengaruh terapi edukasi gizi Encorage and Motivate (EncoMo) terhadap penurunan berat badan pada siswa obesitas di SMPN 164 Jakarta. Metode dalam penelitian ini, menggunakan pendekatan quasy eksperiment dengan pre-test dan post-test with group design. Sampel menerima intervensi pendidikan EncoMo (Dorongan dan Memotivasi). Analisis data menggunakan uji-t independen parametrik atau uji-t berpasangan. Hasil uji menunjukkan bahwa terdapat perbedaan rata-rata pengetahuan (0,000) dan pola konsumsi asupan kalori (0,003) sebelum dan sesudah perlakuan. Hasil uji menunjukkan bahwa tidak ada perbedaan rata-rata pola konsumsi fast food sebelum dan sesudah perlakuan dengan nilai p value (0,007). Hasil uji Body Mass Index menunjukkan nilai p value (0,000) yang artinya rerata Indeks Massa Tubuh (IMT) akan berbeda sebelum dan sesudah perlakuan.
Hubungan Pengetahuan, Sikap, Tindakan, Durasi Tidur dengan Kejadian Anemia pada Remaja Putri di Pondok Pesantren
Authors: Pibriyanti Kartika
Published: July 2024

Anemia di kalangan remaja putri masih menjadi masalah gizi yang perlu penanganan secara serius karena dampak yang ditimbulkan dapat diturunkan pada generasi selanjutnya. Beberapa penelitian menunjukkan bahwa tingkat pengetahuan, sikap dan perilaku makan serta kebiasaan dan kualitas tidur berkaitan dengan masalah anemia. Tujuan penelitian adalah menganalisis hubungan pengetahuan, sikap, tindakan, dan durasi tidur dengan kejadian anemia pada remaja putri di pondok pesantren. Rancangan penelitian menggunakan studi case control dengan pengambilan sampel secara purposive dan melibatkan 47 subjek anemia dan 45 subjek non anemia. Variabel pengetahuan, sikap, tindakan, dan durasi tidur dinilai dengan instrumen kuesioner sedangkan kadar Hb diukur dengan hemoglobinometer. Analisis statistik menggunakan uji komparatif Chi-Square dan Mann Whitney. Diperoleh hasil subjek anemia maupun non anemia memiliki pengetahuan gizi, sikap, dan perilaku yang masuk dalam kategori sedang (60%-80%). Durasi tidur pada kelompok anemia adalah 6 jam sementara non anemia 7 jam. Pengetahuan, sikap, dan perilaku subjek tidak menunjukkan perbedaan yang signifikan. Terdapat perbedaan yang signifikan pada durasi tidur antarat kelompok anemia dan non anemia. Durasi tidur memiliki hubungan yang signifikan terhadap kejadian anemia pada remaja putri.
Ethno and ecotrends in the development of domestic tourism in the context of sustainable development and implementation of industry 5.0
Authors: Koroliuk S. , Maliuta L.
Published: July 2024

The article explores the current trends of domestic tourism in Ukraine, which are being shaped by the impact of military actions, the concept of sustainable development, and Industry 5.0. The main aspects and principles of Industry 5.0 are explored. The key characteristics of the new revolution that influence the development of tourism are identified. The relevance of implementing the principles of the new industry for the tourism sector of Ukraine is substantiated. An analysis of the dynamics of domestic tourism development and statistics of environmentally certified accommodation facilities is carried out. The structural-dynamic paradigm of Industry 5.0 development, the immanent features of Tourism 4.0 and 5.0 are considered. Studying the ambivalence of consumers: the psychological factors influencing the behavior of tourists in the war conditions are explored; the key requests and expectations of consumers regarding domestic tourism are determined; the necessity of further development of eco and ethno tourism taking into account the current realities is substantiated; the promotion of environmentally conscious entrepreneurship is substantiated, which is especially relevant in the context of crimes against the environment caused by russian aggression. Despite the numerous challenges faced by the domestic tourism industry, there is a formation of new super-points of tours, tourist centers of craft, ecological, ethnic, rural and gastronomic types of tourism. Domestic tourism in Ukraine has a great potential for development. This requires cooperation between the state, business and the public, as well as active implementation of new technologies and paradigms, implementation of the strategy of the new industrial revolution.
Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth.
Authors: Yao Yao , Deng Shuhui , Ng Jessica Fong , Yuan Mei , Chakraborty Chandraditya , JoyWeiler Vera , Munshi Nikhil , Fulciniti Mariateresa
Published: July 2024

Multiple myeloma (MM) is a plasma cell malignancy considered incurable despite the recent therapeutic advances. Effective targeted therapies are therefore needed. Our previous studies proved that inhibiting CDK7 impairs the cell cycle and metabolic programs by disrupting E2F1 and MYC transcriptional activities, making it an appealing therapeutic target for MM. Given that CDK7 and BRD4 operate in two distinct regulatory axes in MM, we hypothesized that targeting these two complementary pathways simultaneously would lead to a deeper and more durable response. Indeed, combination therapy had superior activity against MM cell growth and viability, and induced apoptosis to a greater extent than single-agent therapy in both cell lines and patient cells. This synergistic activity was also observed in Waldenström’s Macroglobulinemia (WM) cells and with other inhibitors of E2F1 activity. Dual inhibition effectively impaired the MYC and E2F transcriptional programs and MM tumor growth and progression in xenograft animal models, providing evidence for combination therapy’s potential as a therapeutic strategy in MM and WM.
Caracterización de perfiles hematológicos en razas caninas mediante análisis multivariados
Authors: Sánchez España Álvaro Cecilio , González Rivera Víctor Hugo
Published: July 2024

Introducción. El estudio hematológico es la base del diagnóstico clínico veterinario, este contribuye con información objetiva para la determinación de enfermedades en canes y un tratamiento médico preciso. Objetivo. Es la caracterizar los perfiles hematológicos en razas caninas mediante análisis multivariados. Metodología. Consistió en la recolección de muestras de sangre de siete perros de distintas razas y edades, analizando diversos parámetros hematológicos mediante técnicas de laboratorio. Los resultados se analizaron utilizando estadísticos de comparación de medias y el Análisis de Componentes Principales (ACP). Resultados. el análisis hematológico presentó valores fuera el rango de permisibilidad, lo que conlleva a una causa patológica de anemia. Del análisis de comparación de medias se observó diferencias significativas entre sexo del animal en los parámetros de hematocritos, hemoglobina y recuento de glóbulos rojos.   En el análisis multivariado se identificó cuatro componentes principales que explican el 92,56% de la varianza total en los parámetros hematológicos, revelando patrones de variación relacionados con el tamaño y concentración de glóbulos rojos, eosinófilos, linfocitos y plaquetas. Se observaron diferencias significativas en parámetros como hematocrito, hemoglobina y recuento de glóbulos rojos entre las razas estudiadas. Conclusión. Se concluye que existen variaciones importantes en los parámetros hematológicos entre razas caninas, lo que subraya la necesidad de considerar la raza al interpretar los resultados de análisis de sangre en perros para un diagnóstico más preciso y un tratamiento más efectivo. Área de la ciencia: (Medicina veterinaria)
Studying the change in the length of rock mass transportation when deepening a pit using steeply inclined trenches
Authors: Davidenko N , Anisimov O
Published: July 2024

Purpose. Investigation of the influence of overburden excavation route components on the transportation distance in open pit mining of non-metallic deposits. Methodology. Analysis of existing overburden stripping routes and construction of graphical dependencies of the components taking into account the increase of the exit slope due to the introduction of new types of transportation equipment. Results. The analysis of stripping routes of operating non-metallic quarries has been carried out, which allowed to reveal the peculiarities of the influence of the components of the overburden excavation route on the transportation distance, when using road transport in quarries. The introduction of steep trenches with a slope of 20-45% reduces the transportation distance along the sloping route of the quarry within the range of slope change from 10 to 35% by 10-25%; and further increase in slope does not significantly affect the transportation distance. When establishing the length of transportation, when using steeply sloping exits, it is necessary to take into account that with the increase in the value of the slope should increase the size of the coefficient of route extension. It is established that the height of ledges affects the transportation distance and the dependences of the coefficient of route development on the height of ledges at quarries are obtained. Scientific novelty. The indicators between the components of the highway in the quarry and the assessment of their impact on the transportation distance. The introduction of steep trenches can significantly reduce the transport distance in the open pit, while at the same time significantly increasing the impact of the components of the mine route (junction areas, slopes, turns) on the distance of rock mass transport with a gradual increase in the depth of the pits. Practical significance. The obtained results made it possible to establish the coefficients of the route extension and the working faces with an increase in the slope in the case of using new types of rolling stock. When justifying the route of workings, it is necessary to pay attention to the parameters of various components of the route to ensure the efficiency of transport.
Geometric foundations for the determination of a flat-planetary drill cutting edge deviation
Authors: Dovhal D , Verner I
Published: July 2024

Purpose. The purpose of the work is to establish the function of the deviation of the cutting edge of the tool from the cutting direction, to investigate it and to determine the limit values depending on the values of the design and kinematic parameters of the flat-planetary mining combine drill. Methodology. The basic function of the deviation of the cutting edge of the tool was established by analyzing the functions of the instantaneous values of its coordinates. Graphical and analytical studies of the characteristic forms of the tool’s motion trajectories allowed us to determine the presence of special sections and to investigate them. Results. A method for determining the instantaneous value of the deviation function of the cutting edge of a flat-planetary drill tool has been developed. The presence of special elements on the tool’s trajectory has been established, which lead to its return with the back surface to the cutting direction, which is unacceptable. The obtained dependence of the tool’s cutting edge deviation angle θ on the main parameters of the flat-planetary drill allows, under given constraints, to establish unacceptable parameter ratios based on this indicator. It has been proved that by introducing the concept of the initial angle of the tool installation on the working disk, using the cutting edge deviation indicator, it is possible to determine the zones of effective and ineffective cutting. Scientific novelty. The established dependencies can be applied both to flat-planetary designs of executive bodies and to others, provided that they are linked to the equations of motion of a single cutting tool. The function of the cutting edge deviation angle of the tool allows for its detailed analysis in order to assess the influence of each of the drill parameters and to minimize the difference between critical deviations at different sections of the trajectory. Practical significance. The developed methodology allows us to exclude possible cases of the appearance of cutting edge deviation angles close to extreme values during the tool operation at the design stage. The study of the tool’s motion trajectories based on the deviation criterion will allow for a more rational selection, installation scheme and orientation of the tool, and therefore increase its efficiency.