bluuebunny/crossref_metadata_2025 huggingface dataset:
Fatty Acid Allosteric Regulation of C-H Activation in Plant and Animal Lipoxygenases
Authors: Offenbacher Adam R. , Holman Theodore R.
Published: July 2020

Lipoxygenases (LOXs) catalyze the (per) oxidation of fatty acids that serve as important mediators for cell signaling and inflammation. These reactions are initiated by a C-H activation step that is allosterically regulated in plant and animal enzymes. LOXs from higher eukaryotes are equipped with an N-terminal PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain that has been implicated to bind to small molecule allosteric effectors, which in turn modulate substrate specificity and the rate-limiting steps of catalysis. Herein, the kinetic and structural evidence that describes the allosteric regulation of plant and animal lipoxygenase chemistry by fatty acids and their derivatives are summarized.
Surface Modification of Iron Oxide-Based Magnetic Nanoparticles for Cerebral Theranostics: Application and Prospection
Authors: Wu Yanyue , Lu Zhiguo , Li Yan , Yang Jun , Zhang Xin
Published: July 2020

Combining diagnosis with therapy, magnetic iron oxide nanoparticles (INOPs) act as an important vehicle for drug delivery. However, poor biocompatibility of INOPs limits their application. To improve the shortcomings, various surface modifications have been developed, including small molecules coatings, polymers coatings, lipid coatings and lipopolymer coatings. These surface modifications facilitate iron nanoparticles to cross the blood-brain-barrier, which is essential for diagnosis and treatments of brain diseases. Here we focus on the characteristics of different coated INOPs and their application in brain disease, particularly gliomas, Alzheimer’s disease (AD) and Parkinson’s disease (PD). Moreover, we summarize the current progress and expect to provide help for future researches.
Comprehensive Appraisal of Graphene–Oxide Ratio in Porous Biopolymer Hybrids Targeting Bone-Tissue Regeneration
Authors: Vlasceanu George Mihail , Șelaru Aida , Dinescu Sorina , Balta Cornel , Herman Hildegard , Gharbia Sami , Hermenean Anca , Ionita Mariana , Costache Marieta
Published: July 2020

The bone-tissue engineering (BTE) field is continuously growing due to a major need for bone substitutes in cases of serious traumas, when the bone tissue has reduced capacity for self-regeneration. So far, graphene oxide (GO)-reinforced natural materials provide satisfactory results for BTE, for both in vitro and in vivo conditions. In this study, we aimed to evaluate the biocompatibility of a new biocomposite consisting of chitosan and fish gelatin crosslinked with genipin and loaded with various concentrations of GO (0.5, 1, 2, 3 wt.%) for prospective BTE applications. Scaffold characterizations revealed a constant swelling degree and good resistance to enzyme degradation. The composites presented a porous structure with pores of similar size, thus mimicking the bone structure. In vitro biocompatibility assays demonstrated an overall beneficial interaction between preosteoblasts, and these particular composites, particularly with 0.5 wt.% GO, reinforced composition. Next, the materials were implanted subcutaneously in 6-week old CD1 mice for in vivo evaluation of biocompatibility and inflammatory activity. Immunohistochemical staining revealed maximal cell infiltration and minimal inflammatory reaction for fish gelatin/chitosan/genipin with 0.5 wt.% GO scaffold, thus demonstrating the best biocompatibility for this particular composition, confirming the in vitro results. This study revealed the potential use of fish gelatin/chitosan GO composites for further implementation in the BTE field.
Selection of an Optimal Abrasion Wheel Type for Nano-Coating Wear Studies under Wet or Dry Abrasion Conditions
Authors: Sung Li-Piin , Chung Yu-Fan , Goodwin David G. , Petersen Elijah J. , Hsueh Hsiang-Chun , Stutzman Paul , Nguyen Tinh , Thomas Treye
Published: July 2020

Nanocoatings have numerous potential applications in the indoor environment, such as flooring finishes with increased scratch- and wear-resistance. However, given concerns about the potential environmental and human health effects of nanomaterials, it is necessary to develop standardized methods to quantify nanomaterial release during use of these products. One key choice for mechanical wear studies is the abrasion wheel. Potential limitations of different wheels include the release of fragments from the wheel during abrasion, wearing of the wheel from the abrasion process, or not releasing a sufficient number of particles for accurate quantitative analysis. In this study, we evaluated five different wheels, including a typically used silicon oxide-based commercial wheel and four wheels fabricated at the National Institute of Standards and Technology (NIST), for their application in nanocoating abrasion studies. A rapid, nondestructive laser scanning confocal microscopy method was developed and used to identify released particles on the abraded surfaces. NIST fabricated a high performing wheel: a noncorrosive, stainless-steel abrasion wheel containing a deep cross-patch. This wheel worked well under both wet and dry conditions, did not corrode in aqueous media, did not release particles from itself, and yielded higher numbers of released particles. These results can be used to help develop a standardized protocol for surface release of particles from nanoenabled products using a commercial rotary Taber abraser.
Dynamically Modulating Plasmonic Field by Tuning the Spatial Frequency of Excitation Light
Authors: Wang Sen , Sun Minghua , Wang Shanqin , Fu Maixia , He Jingwen , Li Xing
Published: July 2020

Based on the Fourier transform (FT) of surface plasmon polaritons (SPPs), the relation between the displacement of the plasmonic field and the spatial frequency of the excitation light is theoretically established. The SPPs’ field shifts transversally or longitudinally when the spatial frequency components f x or f y are correspondingly changed. The SPPs’ focus and vortex field can be precisely located at the desired position by choosing the appropriate spatial frequency. Simulation results are in good agreement with the theoretical analyses. Dynamically tailoring the plasmonic field based on the spatial frequency modulation can find potential applications in microparticle manipulation and angular multiplexed SPP focusing and propagation.
Failure to Thrive in the Outpatient Clinic: A New Insight
Authors: Lezo Antonella , Baldini Letizia , Asteggiano Monica
Published: July 2020

Failure to thrive (FTT) is an abnormal growth pattern determined by inadequate nutrition. It is a common problem in children, representing 5% to 10% of patients seen in an outpatient setting. Many definitions have been proposed based on anthropometric deterioration; however, they show poor concordance. No single definition is sufficiently sensitive in identifying faltering growth whilst a combination of multiple criteria seems more accurate. In light of the recent redefinition of pediatric malnutrition as a disequilibrium between requirements and intakes of energy, and macro- and micronutrients, a wider conception of FTT as an unsatisfactory nutritional status related to poor growth and health is useful. Although the most severe problems of micronutrient malnutrition are found in developing countries, people of all regions of the world can be affected by micronutrient deficiencies (MNDs), a form of undernutrition with relevant effects on growth and health. Changes in diets and lifestyle, elimination diets, food insecurity, and food intake disorders create the conditions at risk of faltering growth and MNDs. This new insight integrates the “classical” anthropometric criteria for definition and treatment, in the aim of warranting both a regular increase in size and an overall adequate development and health status.
Uniformity of Food Protein Interpretation Amongst Dietitians for Patients with Phenylketonuria (PKU): 2020 UK National Consensus Statements
Authors: Evans Sharon , Adam Sarah , Adams Sandra , Allen Heather , Ashmore Catherine , Bailey Sarah , Banks Janette , Churchill Harriet , Cochrane Barbara , Cook Jennifer , Dale Clare , Daly Anne , Dixon Marjorie , Dunlop Carolyn , Ellerton Charlotte , Emm Anita , Firman Sarah , Ford Suzanne , French Moira , Gribben Joanna , Grimsley Anne , Herlihy Ide , Hill Melanie , Judd Shirley , Lang Karen , Males Jo , McDonald Joy , McStravick Nicola , Millington Chloe , Newby Camille , Noble Catharine , Pereira Rachel , Pinto Alex , Robertson Louise , Robotham Abigail , Ross Kathleen , Singleton Kath , Skeath Rachel , Terry Allyson , Van Wyk Karen , White Fiona , White Lucy , Wildgoose Jo , Woodall Alison , MacDonald Anita
Published: July 2020

In phenylketonuria (PKU), variable dietary advice provided by health professionals and social media leads to uncertainty for patients/caregivers reliant on accurate, evidence based dietary information. Over four years, 112 consensus statements concerning the allocation of foods in a low phenylalanine diet for PKU were developed by the British Inherited Metabolic Disease Dietitians Group (BIMDG-DG) from 34 PKU treatment centres, utilising 10 rounds of Delphi consultation to gain a majority (≥75%) decision. A mean of 29 UK dietitians (range: 18–40) and 18 treatment centres (range: 13–23) contributed in each round. Statements encompassed all foods/food groups divided into four categories based on defined protein/phenylalanine content: (1) foods high in protein/phenylalanine (best avoided); (2) foods allowed without restriction including fruit/vegetables containing phenylalanine ≤75 mg/100 g and most foods containing protein ≤0.5 g/100 g; (3) foods that should be calculated/weighed as an exchange food if they contain protein exchange ingredients (categorized into foods with a protein content of: >0.1 g/100 g (milk/plant milks only), >0.5 g/100 g (bread/pasta/cereal/flours), >1 g/100 g (cook-in/table-top sauces/dressings), >1.5 g/100 g (soya sauces)); and (4) fruit/vegetables containing phenylalanine >75 mg/100 g allocated as part of the protein/phenylalanine exchange system. These statements have been endorsed and translated into practical dietary management advice by the medical advisory dietitians for the National Society for PKU (NSPKU).
Early-Life Supplementation of Bovine Milk Osteopontin Supports Neurodevelopment and Influences Exploratory Behavior
Authors: Joung Sangyun , Fil Joanne E. , Heckmann Anne B. , Kvistgaard Anne S. , Dilger Ryan N.
Published: July 2020

Introduction: Osteopontin (OPN) is a whey protein found at high concentration in human milk and is involved in processes such as bone cell proliferation and differentiation. Milk OPN has shown to be involved in various aspects of development, including the immune system and gut health. However, the influence of dietary bovine milk OPN inclusion on brain and cognitive development has not been studied extensively until recently. This research examines whether dietary supplementation of bovine milk OPN supports brain and cognitive development in the translational pig model. Methods: From postnatal day (PND) 2 to 34, twenty-one intact male pigs were provided ad libitum access to one of two dietary treatments, a standard soy protein isolate-based milk replacer to serve as a control diet (n = 11) and the same base diet supplemented with bovine milk OPN to serve as a test diet (n = 10). In addition to growth and health outcomes, recognition memory was tested using the novel object recognition (NOR) task from PND 28 to 32, and magnetic resonance imaging was conducted at PND 34 to evaluate brain development. Results: No dietary effects were observed for growth performance or health indices. For the behavioral analysis, pigs that received the test diet exhibited shorter (p < 0.05) latency to the first object visited compared with pigs fed the control diet. Although the control group exhibited novelty preference, there was no difference in recognition index between dietary groups. Neuroimaging outcomes revealed increased (p < 0.05) relative brain volumes of the corpus callosum, lateral ventricle, left and right internal capsule, left and right putamen-globus pallidus, and right hippocampus, and right cortex in the test group. Diffusion tensor imaging revealed higher (p < 0.05) radial diffusivity in the corpus callosum and lower (p < 0.05) fractional anisotropy in pigs provided the test diet. Conclusion: Dietary supplementation of bovine milk OPN increased the relative volume of several brain regions and altered behaviors in the NOR task. Underlying mechanisms of bovine milk OPN influencing the development of brain structures and additional behaviors warrant further investigation.
Effect of Food with Low Enrichment of N-3 Fatty Acids in a Two-Month Diet on the Fatty Acid Content in the Plasma and Erythrocytes and on Cardiovascular Risk Markers in Healthy Young Men
Authors: Jaček Martin , Hrnčířová Dana , Rambousková Jolana , Dlouhý Pavel , Tůma Petr
Published: July 2020

Polyunsaturated fatty acids of the n-3 series (n-3 PUFA) exhibit a number of favorable effects on the human organism and it is desirable to increase their intake in the diet. For this purpose, flaxseed oil was added to a chicken-feed mixture for the production of meat and eggs. The content of n-3 PUFA in the obtained meat was increased from 250 mg (reference value) to 900 mg in 100 g of meat and from 110 mg (reference value) to 190 mg in 100 g of whole egg; the enriched products are designated as omega-3 meat and omega-3 eggs. Omega-3 meat and eggs were subsequently fed for a period of eight weeks in an amount of 480 g of meat and four eggs (228 g netto) a week to a group of 14 healthy volunteers, whose body composition parameters were measured and blood was analyzed biochemically to determine blood lipids, coagulation parameters, plasma, and erythrocyte fatty acid spectrum composition. A control group of 14 volunteers was fed normal chicken and eggs in the same regime. The performed dietary intervention increases the intake of long-chain PUFA (LC-PUFA) by 37 mg per day, which represents 7–15% of the recommended daily dose. The performed tests demonstrated that the consumption of omega-3 enriched meat and eggs significantly increases the content of n-3 PUFA in the erythrocytes, which are a long-term indicator of fatty acid intake. This intervention has no demonstrable effect on the basic body parameters, such as body weight, fat content, Body Mass Index (BMI), and also on the plasma cholesterol level, high-density lipoprotein (HDL), low-density lipoprotein (LDL), blood clotting and inflammation markers, and omega-3 index.
Mediterranean Diet and Endothelial Function: A Review of its Effects at Different Vascular Bed Levels
Authors: Torres-Peña Jose D. , Rangel-Zuñiga Oriol A. , Alcala-Diaz Juan F. , Lopez-Miranda Jose , Delgado-Lista Javier
Published: July 2020

The Mediterranean diet has recently been the focus of considerable attention as a palatable model of a healthy diet. Its influence on many cardiovascular risk factors, combined with its proven effect in reducing the risk of cardiovascular events in primary prevention, has boosted scientific interest in this age-old nutritional model. Many of the underlying mechanisms behind its health-giving effects have been revealed, from the modulation of the microbiota to the function of high-density lipoproteins (HDL), and it seems to deliver its health benefits mainly by regulating several key mechanisms of atherosclerosis. In this review, we will review the evidence for its regulation of endothelial function, a key element in the early and late stages of atherosclerosis. In addition, we will assess studies which evaluate its effects on the functioning of different arterial territory vessels (mainly the microvascular, peripheral and central vascular beds), focusing mainly on the capillary, brachial and carotid arteries. Finally, we will evaluate the molecular mechanisms which may be involved.
A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies
Authors: Alghananim Alaa , Özalp Yıldız , Mesut Burcu , Serakinci Nedime , Özsoy Yıldız , Güngör Sevgi
Published: July 2020

The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in different components, Peceol, Kolliphor EL, and Transcutol were selected as excipients. Pseudo-ternary phase diagrams were constructed, and then SNEDDS formation assessment studies and solubility of DFX in selected SNEDDSs formulations were performed. DFX loaded SNEDDS were prepared and characterized. The optimum DFX-SNEDDS formulations were developed. The relative safety of the optimized SNEDDS formulation was examined in a human immortalized myelogenous leukemia cell line, K562 cells, using the MTT cell viability test. Cytotoxicity studies revealed more cell viability (71.44%) of DFX loaded SNEDDS compared to pure DFX (3.99%) at 40 μM. The selected DFX-SNEDDS formulation was converted into S-SNEDDS by adsorbing into porous carriers, in order to study its dissolution behavior. The in vitro drug release studies indicated that DFX release (Q5%) from S-SNEDDS solidified with Neusilin UFL2 was significantly higher (93.6 ± 0.7% within 5 min) compared with the marketed product (81.65 ± 2.10%). The overall results indicated that the S-SNEDDS formulation of DFX could have the potential to enhance the solubility of DFX, which would in turn have the potential to improve its oral bioavailability as a safe novel delivery system.
Antioxidant Activity of Synthetic Polymers of Phenolic Compounds
Authors: Nagarajan Subhalakshmi , Nagarajan Ramaswamy , Kumar Jayant , Salemme Adele , Togna Anna Rita , Saso Luciano , Bruno Ferdinando
Published: July 2020

In recent years, developing potent antioxidants has been a very active area of research. In this context, phenolic compounds have been evaluated for their antioxidant activity. However, the use of phenolic compounds has also been limited by poor antioxidant activity in several in vivo studies. Polymeric phenols have received much attention owing to their potent antioxidant properties and increased stability in aqueous systems. To be truly effective in biological applications, it is important that these polymers be synthesized using benign methods. In this context, enzyme catalyzed synthesis of polymeric phenols has been explored as an environmentally friendly and safer approach. This review summarizes work in enzymatic syntheses of polymers of phenols. Several assays have been developed to determine the antioxidant potency of these polymeric phenols. These assays are discussed in detail along with structure-property relationships. A deeper understanding of factors affecting antioxidant activity would provide an opportunity for the design of versatile, high performing polymers with enhanced antioxidant activity.
Antibacterial Activity of Biocellulose with Oregano Essential Oil against Cronobacter Strains
Authors: Nagmetova Gulden , Berthold-Pluta Anna , Garbowska Monika , Kurmanbayev Askar , Stasiak-Różańska Lidia
Published: July 2020

Biocellulose, named “the biomaterial of the future”, is a natural and ecologically friendly polymer, produced by selected acetic acid bacteria strains. Biocellulose impregnated with antimicrobial agents can be used as a novel, safe, and biodegradable food packaging material, helping extend the shelf life of some products and may also have the chance to replace typical plastic packaging, which is a big environmental problem these days. This study aimed to evaluate if cellulose impregned with natural oregano essential oil could show antibacterial activity against Cronobacter strains, which can occur in food, causing diseases and food poisoning. Bacterial cellulose was obtained from two acetic bacteria strains, Gluconacetobacter hansenii ATCC 23769 and Komagataeibacter sp. GH1. Antibacterial activity was studied by the disc-diffusion method against chosen Cronobacter strains, isolated from the plant matrix. Oregano essential oil has been shown to penetrate into the structure of bacterial cellulose, and after applying cellulose to the solid medium, it showed the ability to migrate. Biopolymer from the strain K. sp. GH1 was able to better absorb and retain essential oregano oil (OEO) compared to bacterial cellulose (BC) produced by the G. hansenii ATCC 23769. Bacterial cellulose with oregano essential oil from strain Komagataeibacter GH1 showed generally greater inhibitory properties for the growth of tested strains than its equivalent obtained from G. hansenii. This was probably due to the arrangement of the polymer fibers and its final thickness. The largest zone of inhibition of strain growth was observed in relation to C. condimenti s37 (32.75 mm ± 2.8). At the same time, the control sample using filter paper showed an inhibition zone of 36.0 mm ± 0.7. A similar inhibition zone (28.33 mm ± 2.6) was observed for the C. malonaticus lv31 strain, while the zone in the control sample was 27.1 mm ± 0.7. Based on this study, it was concluded that bacterial cellulose impregnated with oregano essential oil has strong and moderate antimicrobial activity against all presented strains of the genus Cronobacter isolated from plant matrix. Obtained results give a strong impulse to use this biopolymer as ecological food packaging in the near future.
Isolation and Biophysical Characterisation of Bioactive Polysaccharides from Cucurbita Moschata (Butternut Squash)
Authors: Jiwani Shahwar Imran , Gillis Richard B. , Besong David , Almutairi Fahad , Erten Tayyibe , Kök M. Samil , Harding Stephen E. , Paulsen Berit S. , Adams Gary G.
Published: July 2020

Cucurbits are plants that have been used frequently as functional foods. This study includes the extraction, isolation, and characterisation of the mesocarp polysaccharide of Cucurbita moschata. The polysaccharide component was purified by gel filtration into three fractions (NJBTF1, NJBTF2, and NJBTF3) of different molecular weights. Characterisation includes the hydrodynamic properties, identification of monosaccharide composition, and bioactivity. Sedimentation velocity also indicated the presence of small amounts of additional discrete higher molecular weight components even after fractionation. Sedimentation equilibrium revealed respective weight average molecular weights of 90, 31, and 19 kDa, with the higher fractions (NJBTF1 and NJBTF2) indicating a tendency to self-associate. Based on the limited amount of data (combinations of 3 sets of viscosity and sedimentation data corresponding to the 3 fractions), HYDFIT indicates an extended, semi-flexible coil conformation. Of all the fractions obtained, NJBTF1 showed the highest bioactivity. All fractions contained galacturonic acid and variable amounts of neutral sugars. To probe further, the extent of glycosidic linkages in NJBTF1 was estimated using gas chromatography–mass spectrometry (GCMS), yielding a high galacturonic acid content (for pectin polysaccharide) and the presence of fructans—the first evidence of fructans (levan) in the mesocarp. Our understanding of the size and structural flexibility together with the high bioactivity suggests that the polysaccharide obtained from C. moschata has the potential to be developed into a therapeutic agent.
Strength Degradation in Curved Fiber-reinforced Polymer (FRP) Bars Used as Concrete Reinforcement
Authors: Imjai Thanongsak , Garcia Reyes , Guadagnini Maurizio , Pilakoutas Kypros
Published: July 2020

Steel reinforcements in concrete tend to corrode and this process can lead to structural damage. Fiber-reinforced polymer (FRP) reinforcements represent a viable alternative for structures exposed to aggressive environments and have many possible applications where superior corrosion resistance properties are required. The use of FRP rebars as internal reinforcements for concrete, however, is limited to specific structural elements and does not yet extend to the whole structure. The reason for this relates to the limited availability of curved or shaped reinforcing FRP elements on the market, as well as their reduced structural performance. This article presents a state-of-the art review on the strength degradation of curved FRP composites, and also assesses the performance of existing predictive models for the bend capacity of FRP reinforcements. Previous research has shown that the mechanical performance of bent portions of FRP bars significantly reduces under a multiaxial combination of stresses. Indeed, the tensile strength of bent FRP bars can be as low as 25% of the maximum tensile strength developed in a straight counterpart. In a significant number of cases, the current design recommendations for concrete structures reinforced with FRP were found to overestimate the bend capacity of FRP bars. A more accurate and practical predictive model based on the Tsai–Hill failure criteria is also discussed. This review article also identifies potential challenges and future directions of research for exploring the use of curved/shaped FRP composites in civil engineering applications.
The UAS-Based 3D Image Characterization of Mozarabic Church Ruins in Bobastro (Malaga), Spain
Authors: Enríquez Carlos , Jurado Juan Manuel , Bailey Alexandro , Callén Danilo , Collado María José , Espina Gabriel , Marroquín Pablo , Oliva Erick , Osla Edgar , Ramos María Isabel , Sarceño Scarlett , Feito Francisco Ramón
Published: July 2020

In recent years, the application of geomatics tools in archaeology has proved to be very useful to obtain meaningful knowledge of the 3D reconstruction of archaeological remains and semantic classification of the 3D surface. These techniques have proven to be an effective solution for the 3D modeling and the extraction of many spatial features on an archaeological site. However, novel methodologies as well as new data exploitation strategies are required to exploit these geospatial data for natural and cultural heritage documentation, monitoring, and preservation. In this paper, we have studied unique archaeological ruins, a Mozarab church in Al-Andalus, using high-resolution RGB images, which was taken by a drone. Thus, a 3D reconstruction of the ruins and the surrounding environment is carried out in order to characterize it on a dense point cloud. Then, a digital elevation model (DEM) was calculated in order to identify critical slope lines, which are significant to determine where the structure of the church was built. Our results can be used for the development of an architectural project and thus a virtual recreation of these archaeological ruins was performed.
Assessment of Tree Detection Methods in Multispectral Aerial Images
Authors: Pulido Dagoberto , Salas Joaquín , Rös Matthias , Puettmann Klaus , Karaman Sertac
Published: July 2020

Detecting individual trees and quantifying their biomass is crucial for carbon accounting procedures at the stand, landscape, and national levels. A significant challenge for many organizations is the amount of effort necessary to document carbon storage levels, especially in terms of human labor. To advance towards the goal of efficiently assessing the carbon content of forest, we evaluate methods to detect trees from high-resolution images taken from unoccupied aerial systems (UAS). In the process, we introduce the Digital Elevated Vegetation Model (DEVM), a representation that combines multispectral images, digital surface models, and digital terrain models. We show that the DEVM facilitates the development of refined synthetic data to detect individual trees using deep learning-based approaches. We carried out experiments in two tree fields located in different countries. Simultaneously, we perform comparisons among an array of classical and deep learning-based methods highlighting the precision and reliability of the DEVM.
Physics-based Bathymetry and Water Quality Retrieval Using PlanetScope Imagery: Impacts of 2020 COVID-19 Lockdown and 2019 Extreme Flood in the Venice Lagoon
Authors: Niroumand-Jadidi Milad , Bovolo Francesca , Bruzzone Lorenzo , Gege Peter
Published: July 2020

The recent PlanetScope constellation (130+ satellites currently in orbit) has shifted the high spatial resolution imaging into a new era by capturing the Earth’s landmass including inland waters on a daily basis. However, studies on the aquatic-oriented applications of PlanetScope imagery are very sparse, and extensive research is still required to unlock the potentials of this new source of data. As a first fully physics-based investigation, we aim to assess the feasibility of retrieving bathymetric and water quality information from the PlanetScope imagery. The analyses are performed based on Water Color Simulator (WASI) processor in the context of a multitemporal analysis. The WASI-based radiative transfer inversion is adapted to process the PlanetScope imagery dealing with the low spectral resolution and atmospheric artifacts. The bathymetry and total suspended matter (TSM) are mapped in the relatively complex environment of Venice lagoon during two benchmark events: The coronavirus disease 2019 (COVID-19) lockdown and an extreme flood occurred in November 2019. The retrievals of TSM imply a remarkable reduction of the turbidity during the lockdown, due to the COVID-19 pandemic and capture the high values of TSM during the flood condition. The results suggest that sizable atmospheric and sun-glint artifacts should be mitigated through the physics-based inversion using the surface reflectance products of PlanetScope imagery. The physics-based inversion demonstrated high potentials in retrieving both bathymetry and TSM using the PlanetScope imagery.
Deriving Wheat Crop Productivity Indicators Using Sentinel-1 Time Series
Authors: Vavlas Nikolaos-Christos , Waine Toby W. , Meersmans Jeroen , Burgess Paul J. , Fontanelli Giacomo , Richter Goetz M.
Published: July 2020

High-frequency Earth observation (EO) data have been shown to be effective in identifying crops and monitoring their development. The purpose of this paper is to derive quantitative indicators of crop productivity using synthetic aperture radar (SAR). This study shows that the field-specific SAR time series can be used to characterise growth and maturation periods and to estimate the performance of cereals. Winter wheat fields on the Rothamsted Research farm in Harpenden (UK) were selected for the analysis during three cropping seasons (2017 to 2019). Average SAR backscatter from Sentinel-1 satellites was extracted for each field and temporal analysis was applied to the backscatter cross-polarisation ratio (VH/VV). The calculation of the different curve parameters during the growing period involves (i) fitting of two logistic curves to the dynamics of the SAR time series, which describe timing and intensity of growth and maturation, respectively; (ii) plotting the associated first and second derivative in order to assist the determination of key stages in the crop development; and (iii) exploring the correlation matrix for the derived indicators and their predictive power for yield. The results show that the day of the year of the maximum VH/VV value was negatively correlated with yield (r = −0.56), and the duration of “full” vegetation was positively correlated with yield (r = 0.61). Significant seasonal variation in the timing of peak vegetation (p = 0.042), the midpoint of growth (p = 0.037), the duration of the growing season (p = 0.039) and yield (p = 0.016) were observed and were consistent with observations of crop phenology. Further research is required to obtain a more detailed picture of the uncertainty of the presented novel methodology, as well as its validity across a wider range of agroecosystems.
A Survey on the Evolution of Opportunistic Routing with Asynchronous Duty-Cycled MAC in Wireless Sensor Networks
Authors: Lata Ayesha Akter , Kang Moonsoo
Published: July 2020

Wireless sensor networks (WSNs) have been used for environmental monitoring and reporting for many decades. Energy consumption is a significant research topic because wireless sensor nodes are battery-operated to be highly energy-constrained. Several strategies have been introduced in routing and MAC (Medium Access Control) layer protocols to facilitate energy saving. At the routing layer, an energy-efficient routing protocol, known as opportunistic routing (OR), has been designed to improve efficiency. OR achieves energy efficiency via load-balancing, which forwards packets along multiple routes over WSNs. At the MAC layer, an energy-efficient MAC protocol known as the asynchronous duty-cycled MAC (ADCM) protocol achieves energy saving by turning on and off a sensor node’s transmitter and receiver to eliminate unnecessary energy wastage. These protocols each have their own advantages and disadvantages. OR achieves energy efficiency at the routing layer but it raises an issue at the MAC layer. ADCM achieves energy efficiency at the MAC layer, but it hinders the packet forwarding efficiency of the OR. To attain better energy efficiency, a combination of these two ideas led to the development of OR with asynchronous duty-cycled MAC (OR-ADCM). However, even with better energy efficiency, limitations still exist in combining load-balancing and duty-cycling due to conflicts in the inherent properties of OR and ADCM. In this paper, we present a survey of the evolution of OR-ADCM over WSNs to help the reader better understand and appreciate the details of this tradeoff, which we hope will lead to the development of better protocol designs.
Active Volume Control in Smart Phones Based on User Activity and Ambient Noise
Authors: Ambeth Kumar V. D. , Malathi S. , Kumar Abhishek , M Prakash , Veluvolu Kalyana C.
Published: July 2020

To communicate efficiently with a prospective user, auditory interfaces are employed in mobile communication devices. Diverse sounds in different volumes are used to alert the user in various devices such as mobile phones, modern laptops and domestic appliances. These alert noises behave erroneously in dynamic noise environments, leading to major annoyances to the user. In noisy environments, as sounds can be played quietly, this leads to the improper masked rendering of the necessary information. To overcome these issues, a multi-model sensing technique is developed as a smartphone application to achieve automatic volume control in a smart phone. Based on the ambient environment, the volume is automatically controlled such that it is maintained at an appropriate level for the user. By identifying the average noise level of the ambient environment from dynamic microphone and together with the activity recognition data obtained from the inertial sensors, the automatic volume control is achieved. Experiments are conducted with five different mobile devices at various noise-level environments and different user activity states. Results demonstrate the effectiveness of the proposed application for active volume control in dynamic environments.
3D Microfluidic Devices in a Single Piece of Paper for the Simultaneous Determination of Nitrite and Thiocyanate
Authors: Yu Peng , Deng Muhan , Yang Yi , Nie Beixi , Zhao Shaoyu
Published: July 2020

The concentrations of nitrite and thiocyanate in saliva can be used as the biomarkers of the progression of periodontitis disease and environmental tobacco smoke exposure, respectively. Therefore, it is particularly necessary to detect these two indicators in saliva. Herein, the three-dimensional single-layered paper-based microfluidic analytical devices (3D sl-μPADs) were, for the first time, fabricated by the spraying technique for the colorimetric detection of nitrite and thiocyanate at the same time. The conditions for 3D sl-μPADs fabrication were optimized in order to well control the penetration depth of the lacquer in a paper substrate. Then, the developed 3D sl-μPADs were utilized to simultaneously detect nitrite and thiocyanate and the limits of detection are 0.0096 and 0.074 mM, respectively. What is more, the μPADs exhibited good specificity, good repeatability, and acceptable recoveries in artificial saliva. Therefore, the developed 3D sl-μPADs show a great potential to determine nitrite and thiocyanate for the assessment of the human health.
Real-Time Object Tracking via Adaptive Correlation Filters
Authors: Du Chenjie , Lan Mengyang , Gao Mingyu , Dong Zhekang , Yu Haibin , He Zhiwei
Published: July 2020

Although correlation filter-based trackers (CFTs) have made great achievements on both robustness and accuracy, the performance of trackers can still be improved, because most of the existing trackers use either a sole filter template or fixed features fusion weight to represent a target. Herein, a real-time dual-template CFT for various challenge scenarios is proposed in this work. First, the color histograms, histogram of oriented gradient (HOG), and color naming (CN) features are extracted from the target image patch. Then, the dual-template is utilized based on the target response confidence. Meanwhile, in order to solve the various appearance variations in complicated challenge scenarios, the schemes of discriminative appearance model, multi-peaks target re-detection, and scale adaptive are integrated into the proposed tracker. Furthermore, the problem that the filter model may drift or even corrupt is solved by using high confidence template updating technique. In the experiment, 27 existing competitors, including 16 handcrafted features-based trackers (HFTs) and 11 deep features-based trackers (DFTs), are introduced for the comprehensive contrastive analysis on four benchmark databases. The experimental results demonstrate that the proposed tracker performs favorably against state-of-the-art HFTs and is comparable with the DFTs.
A Kalman Filter-Based Method for Diagnosing the Structural Condition of Medium- and Small-Span Beam Bridges during Brief Traffic Interruptions
Authors: Gao Qingfei , Wang Xiang , Liu Yang
Published: July 2020

Load tests are a popular way to diagnose the structural condition of bridges, however, such tests usually interrupt traffic for many hours. To address this issue, a Kalman filter-based method is proposed to diagnose the structural condition of medium- and small-span beam bridges by using the acceleration responses obtained from the bridge during a brief traffic interruption. First, a condition diagnosis feature based on the Kalman filter innovation (i.e., the optimal difference between the filter predictions and measured responses) is presented. Second, a condition diagnosis index, which is the energy ratio between the innovation and the measured acceleration, is generated by calculating the null space of the Hankel matrix consisting of condition diagnosis features. Then, on the basis of the novel detection, a method is used to diagnose the structural condition of a bridge during a brief traffic interruption. Finally, the validity and dependability of the proposed method is demonstrated through experimental tests with a model bridge and field tests on an actual bridge. Using the proposed method, the long-time interruption of traffic flow and the reliance on finite element model are effective avoided during the process of condition diagnosis of bridges.
Economic Impact Assessment of Regulatory Changes: A Case Study of a Proposed New ICAO Standard for Contaminated Runways
Authors: Bråthen Svein , Hoff Karoline L.
Published: July 2020

The literature on economic impact assessments (EIA) of regulatory changes in the transport sector is scarce. This study examines how a change in the regulatory framework for air transport could affect transport costs. The case in question is the International Civil Aviation Organization (ICAO) State letter AN 4/1.2.26-16/19 that proposed to set a higher minimum friction on runways operated during slippery conditions. This may affect operations, particularly in the northern hemisphere. Four Norwegian airports that operate under severe winter conditions are used as examples. Sudden cancellations or transfers to another airport give additional costs per passenger, ranging from NOK 750 to NOK 5600 per return flight. If these results are generalized to all affected flights in Norway, the annual estimate is NOK 400–450 million. These numbers may not seem exorbitant. However, the costs are mainly borne by a limited number of airports. Some of them may have to close during winter, with severe consequences for local communities. This study illustrates how effects of a proposed regulatory change may be assessed in order to aid the decision-making process. The impacts on aviation safety are not considered. Data on aircraft accidents in Norway do not indicate significant effects from the proposed regulatory change.
Factors Influencing Competitiveness in the Global Beer Trade
Authors: Török Áron , Szerletics Ákos , Jantyik Lili
Published: July 2020

Beer is a widely produced, consumed, and traded alcoholic drink all around the world. This paper investigates the factors influencing competitiveness in the global beer trade on the macroeconomic level. To reach this aim, descriptive analysis and panel regression together with stability tests were used on the global beer market from 1998 to 2017. Results showed high concentration both in global production and trade, while except for the most competitive beer-exporting countries, the level of comparative advantages has significantly changed in these three decades. Based on the panel regression models, total beer production and per capita consumption, EU membership, and the number of beers with geographical indications have a positive impact on comparative advantages. In contrast, barley production, level of foreign direct investments, size of the population, GDP/capita, and high quality level of the beer export have a negative effect.
Connecting Public Policies for Family Farmers and Women’s Empowerment: The Case of the Brazilian Semi-Arid
Authors: Brandão Emily Aparecida Ferreira , Santos Thiago da Rocha , Rist Stephan
Published: July 2020

The role played by women in worldwide food production and food security has reinvigorated debates about the recognition of women’s rights in the rural sector regarding better working conditions and the reduction of gender inequalities. In the 1980s, the social movement in Brazil restructured the politics in the agrarian sector by integrating farmers’ rights and women’s demands. Against this background, the objective of this study is to analyze, through the actors’ perspectives, whether and how the combination of public policies for family farmers affected the socio-economic and political empowerment of women. Our case study covers family farmers from traditional communities located in the Brazilian semi-arid. The results show that women achieved economic stability by participating in public food procurement programmes. In addition, access to cisterns released women from the daily work of collecting water. Women became more involved with political issues, increasing participation in institutions such as NGOs, associations and cooperatives. Among the negative aspects, the study found that the sexual division of labor increased within the household context, and, despite being fundamental for ensuring household food security, women still struggle to have access to the means of production.
Sustainable and Integrated Urban Planning and Governance in Metropolitan and Medium-Sized Cities
Authors: Medeiros Eduardo , van der Zwet Arno
Published: July 2020

This paper examines the design and implementation process of Integrated Strategies for Sustainable Urban Development (ISUD), as well as their main effects and lessons learned in two European cities: Barcelona in Spain, a vibrant European metropolis, and Évora in Portugal, a medium-sized city with a world heritage historic centre. The former is facing socioeconomic challenges in some of its neighbourhoods, while the latter, a regional capital of an already depopulated region, Alentejo, is facing further depopulation and socioeconomic challenges. Following from a qualitative analysis of ISUD and other urban plans implemented in past decades, the article employs a framework with five analytical dimensions, based on the policy cycle (priority setting, participatory approaches, implementation strategy, collaboration networks, and measuring results and impact). These provide a framework to identify best practices. The findings demonstrate that ISUD in both cities provides impetus for sustainable strategic planning, but can be strengthened in particular via the active involvement of citizens and stakeholders in the elaboration and implementation of these ISUD. Conversely, the results demonstrate mounting challenges that many urban planners in medium-sized towns face in relation to inverting depopulation trends, raising further questions of to what extent European Cohesion policy, and ISUD in particular, can contribute to territorial cohesion objectives whilst also aiming to achieve other policy goals.
Regional Flexible Surge Capacity—A Flexible Response System
Authors: Glantz Viktor , Phattharapornjaroen Phatthranit , Carlström Eric , Khorram-Manesh Amir
Published: July 2020

Surge capacity is the ability to manage the increased influx of critically ill or injured patients during a sudden onset crisis. During such an event, all ordinary resources are activated and used in a systematic, structured, and planned way to cope with the situation. There are, however, occasions where conventional healthcare means are insufficient, and additional resources must be summoned. In such an event, the activation of existing capabilities within community resources can increase regional surge capacity in a flexible manner. These additional resources together represent the concept of Flexible Surge Capacity. This study aims to investigate the possibility of establishing a Flexible Surge Capacity response system to emergencies by examining the main components of surge capacity (Staff, Stuff, Structure, System) within facilities of interest present in the Western Region of Sweden. Through a mixed-method and use of (A) questionnaires and (B) semi-structured key-informant interviews, data was collected from potential alternative care facilities to determine capacities and capabilities and barriers and limitations as well as interest to be included in a flexible surge capacity response system. Both interest and ability were found in the investigated primary healthcare centers, veterinary and dental clinics, schools, and sports and hotel facilities to participate in such a system, either by receiving resources and/or drills and exercises. Barriers limiting the potential participation in this response system consisted of a varying lack of space, beds, healthcare materials, and competencies along with a need for clear organizational structure and medical responsibility. These results indicate that the concept of flexible surge capacity is a feasible approach to emergency management. Educational initiatives, drills and exercises, layperson empowerment, organizational and legal changes and sufficient funding are needed to realize the concept.