bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Sistem Rekomendasi Wisata Berbasis Teknologi Untuk Optimalisasi Pengelolaan Pantai Manggar Di Kota Balikpapan
Authors: Maulida Nabila Cahaya , Hasrullah Hasrullah
Published: January 2025

Pantai Manggar di Kota Balikpapan memiliki potensi besar sebagai destinasi wisata unggulan. Namun, berbagai tantangan, seperti kurangnya pengelolaan fasilitas, masalah lingkungan, dan aksesibilitas informasi, menghambat pengelolaan yang optimal. Penelitian ini bertujuan untuk mengembangkan sistem rekomendasi wisata berbasis teknologi guna mendukung optimalisasi pengelolaan Pantai Manggar. Penelitian ini menggunakan pendekatan kuantitatif dengan algoritma Content-Based Filtering, Principal Component Analysis (PCA), dan Support Vector Machine (SVM). Data dikumpulkan melalui kuesioner, wawancara, dan observasi langsung, dengan responden terdiri dari wisatawan dan pelaku usaha lokal. Data dianalisis menggunakan teknik deskriptif dan evaluasi kinerja sistem berdasarkan akurasi, presisi, dan efisiensi algoritma. Hasil penelitian menunjukkan bahwa sistem rekomendasi berbasis PCA dan SVM mencapai akurasi hingga 93%, yang mampu memberikan rekomendasi yang relevan dan personal bagi pengguna. Implementasi sistem ini juga berdampak pada peningkatan jumlah kunjungan wisata hingga 20% dalam periode uji coba, serta peningkatan pendapatan destinasi wisata. Penelitian ini memberikan implikasi penting terhadap pengembangan teknologi dalam sektor pariwisata, khususnya dalam mengatasi tantangan pengelolaan destinasi lokal. Sistem rekomendasi ini tidak hanya meningkatkan pengalaman wisatawan, tetapi juga mendorong keberlanjutan lingkungan dan ekonomi. Untuk penelitian selanjutnya, integrasi kecerdasan buatan dan analisis aspek sosial budaya dapat menjadi fokus pengembangan lebih lanjut.
Vaccination with Delta-PGM in the control of buffalo (Bubalus bubalis) brucellosis
Authors: Sánchez-Villalobos Alfredo , Salas Leandro , Fuenmayor Hengelbert , Contreras Omaira , Machado Enmanuel
Published: January 2025

Brucellosis in buffalos represents an unresolved problem for consolidating the species in Venezuela. In 2020, a control program started in 5 associated farms with an estimated ˃ 20% prevalence. The program focused on: vaccination with Delta-PGM (Agropharma Laboratories, Buenos Aires, Argentina), 2ml subcutaneous injection in 3- to- 8- month females, aiming to secure two dosages before the service (2nd dosage seven months after the first), and detection/elimination of the infected through serial diagnosis with buffered plate antigen test (BPA, Agropharma Laboratories, Buenos Aires, Argentina) and fluorescence polarization assay (FPA, Biotehnika Laboratories, Serbia). The objectives included showing the vaccine’s pro-tection capacity against the disease in natural conditions with important naturally occurring challenges (prevalence ˃ 20%) and differentiating infected from vaccinated animals (DIVA) with the previously described diagnostic test. In October 2022, diagnostic evaluation was carried out in 1,340 replacement females from this system, vaccinated or not, and divided into four groups according to body weight (G1: less than 170 k; G2: between 171 and 220; G3: from 221 to 270; G4: above 270 k). The data were analyzed through Friedman’s non-parametric statistical test, allowing comparisons between the observed characters. Ninety animals (90) without vaccination were detected, belonging to groups G1 and G2, one being positive for brucellosis (1/90; 1.11%; p>0.05). Of the total evaluated population, 47 were reactive to BPA (47/1340; 3.5%), and only 16 were confirmed positive for brucellosis with FPA (16/1340; 1.2%; p<0.05). Of them, 8 (50%) belonged to G2 and another 8 (50%) to G3, without detection in G1 or G4, showing statistical differences (p<0.05). Regarding the vaccination and positivity correlation, it is noteworthy that 14 (14/1160; 1.20%) of the positives for brucellosis had received primary vaccination and a booster; none with two boosters was identified as positive (p<0.05). On the other hand, it stands out that three positives had a history, as they came from mothers reported to be reactive to BPA. Concerning the origin of the positives, the majority (68.8%) belonged to two problem farms (p<0.05). In conclusion, under the studied conditions, a high efficiency of the established control model was verified, which was associated with the protective capacity of the Delta- PGM strain vaccine. Using two applications prior to service, this model resulted in a significant reduction of infections in relation to their dams (p<0.05). It also showed that Delta-PGM allows differentiation between infected, vaccinated, and healthy animals (DIVA); therefore, its use does not lead to any diagnostic confusion when using BPA and/or FPA.
Serum calcium and its relationship with immunoglobulin G (IgG) levels in prepartum buffaloes from the Venezuelan humid tropics
Authors: Uzcátegui-Varela Juan Pablo , Urbina Andueza Anacelmira , Caamaño Carrero Janeth
Published: January 2025

The immune system partially recognizes specific antigens due to the role of calcium (Ca2+) as an intracellular second messenger that regulates the humoral immune response. To consider a physiological association  between serum Ca2+ levels and its modulatory effect on immunoglobulin G (IgG) synthesis before calving in dairy buffaloes (Bubalus bubalis) in southern Lake Maracaibo, Venezuela, twenty clinically healthy Murrah x Mediterranean crossbred female buffaloes with excellent body condition were considered for this study. Ten were young females of 33.6±14.15 months, with nine months of gestation and 432±44.27 kg body weight. The other ten were adult buffaloes of 563±53.6 kg body weight at nine months of gestation and reproductive history of four calvings. The sampling consisted of collecting 6 milliliters (mL) of blood by jugular venipuncture in tubes without anticoagulant; then, the serum was separated by centrifugation at 3,300 r.p.m. for 20 minutes at 25 °C using a BOECO®-Germany centrifuge. Next, 1 mL of serum was taken to determine the serological parameters under study. Ca2+ was found in the blood through the Arsenazo III method using a Selectra ProsS ELITech®- Netherlands Analyzer and, to quantify the levels of IgG; the immunoturbidimetry technique was used with the Cobas c311 Roche® Analyzer®-USA. The data were subjected to the Kruskal-Wallis nonparametric test and Spearman correlation analysis. According to the results obtained, primiparous B. bubalis females close to parturition presented serum Ca2+ levels (8.03±0.25 mg/dL) similar to multiparous buffaloes (8.07±0.7 mg/dL) adjusted to the reference range (6.05-11.98 mg/dL) for water buffaloes. In contrast, IgG in young females was higher (761.33±21.81 mg/dL) concerning adult buffaloes (735. 83±17.39 mg/dL) with no statistically significant differences (p>0.05) between groups for both variables; however, the correlation test indicated that, in first calving buffaloes, the circulating Ca2+ level is negatively associated (r=-0.56) with IgG concentration, a physiological response that was statistically different (p<0.05) concerning multiparous buffaloes (r=0.83). There is evidence of an association between serum calcium concentration and IgG levels that depends on the number of calvings, possibly because different metabolic pathways for Ca 2+ exchange determine the immune response among the categories of buffaloes included in the study. Thus, the functional significance of Ca2+ signaling for the prepartum B. bubalis immune system is just beginning to emerge.
Irony, Philosophy, and Revolution
Authors: Miller Paul Allen
Published: January 2025

If we “do justice” to Socrates—not as the Athenian people did, which Hegel considered just and necessary—but if we let him roam free, if we set no limit to the testing he does of us and our fellow citizens, then the Socratic impulse is both profoundly ironic and ultimately revolutionary: for this moment of irony is that in which new thought and new concepts can emerge, and this moment is a necessary, if not sufficient, cause of fundamental social change. To make this case for the revolutionary potential of irony and the movement of the concept, I enlist the help of Jacques Derrida. In particular, I will make use of his notion of “hauntology” as elaborated in Spectres of Marx and related works from the eighties and nineties.
Steps in Time
Authors: Dougherty Carol
Published: January 2025

This paper argues that the aporia at the heart of  Derrida’s essay on hospitality — its absence, its transgressions, its digressions – perfectly describes the narrative landscape of Cormac McCarthy’s 2006 novel, The Road.  Following  Derrida along McCarthy’s post-apocalyptic road allows the reader to explore the impossible hospitality of a world in which a man and his son must travel without the comforts of home or the safety of houses.  It also suggests the opposite – revealing the experience of homelessness as the pre-condition, both ethical and imaginative, for defining hospitality, our ways of relating to others, as others.  The novel’s aporetic conclusion reduces the novel’s protracted engagement with hospitality and its absence to the simple gesture of accepting what comes (à venir), a gesture that will, in the end, provide a future (l’avenir). Derrida’s meditations on hospitality repeatedly invoke the mythic figure of Oedipus, and this essay concludes by suggesting that reading Oedipus’ death as a final, transgressive act of hospitality might spark new insights into the man’s death in The Road as well as how a Derridean reading of the impossible poetics of hospitality in The Road prompts a similarly productive engagement with time in Sophocles’ Oedipus at Colonus.
Blanchot, Derrida, and the Gimmick
Authors: Telò Mario
Published: January 2025

According to Blanchot, “disaster is its imminence…what escapes the very possibility of experience.” This notion of disaster confounds the Derridean a-venir, since it concerns “what one cannot welcome except as the immanence that gratifies.” In this chapter, I use Blanchot’s engagement with Derrida as well as Derrida’s discussion of him in Demeure to reconsider the sense of disaster in Euripides’ Bacchae. Instead of focusing on the Maenads’ vitalistic rage, I linger on an apparently problematic scene: the enactment of Dionysian transgender rituals by two old men, Tiresias and Cadmus. Their jouissance lies in a gratifying passivity before the imminence that, for Blanchot, is dis-aster. In this scene, a prolonged present provoked by a not-yet-materialized catastrophic present evokes the temporality of the “gimmick,” which, for Sianne Ngai, confronts us with “a mode of bad contemporaneity akin to an elongated present.” I dwell on the temporality of hesitation as an alternative that Bacchae offers to the manic claims of decision-making and the future. While waiting is at once an unwelcome intrusion in the Covid era and the perennial condition of the migrants and refugees denied coevalness, in the context of the play the “arrival” (venir) of a “lack” (a-) constituted by the act of waiting and the in-decision of the present’s immobility has the potential to forestall the deceptively liberating future of ecstatic Dionysian time, replacing it with an extended (differently) Dionysian chronicity.
Pengembangan Media Pembelajaran Matematika Edukatif Berbasis Video Animasi Terhadap Kemampuan Pemahaman Matematis Siswa Pada Materi Teori Peluang
Authors: Yuliniar Sesilia , Ardiawan Yadi , Oktaviana Dwi
Published: January 2025

Penelitian ini bertujuan untuk menghasilkan media pembelajaran berupa media pembelajaran matematika edukatif berbasis video animasi terhadap kemampuan pemahaman matematis siswa pada materi teori peluang di kelas VIII SMP Mandiri Pontianak. Penelitian ini merupakan penelitian pengembangan (R&D) dengan prosedur penelitian yang menggunakan model ADDIE. Subjek dalam penelitian ini terdiri atas ahli (validator) dan siswa (subjek uji coba produk). Teknik pengumpulan data dalam penelitian ini adalah Teknik komunikasi tidak langsung dengan instrumen penelitian berupa lembar validasi ahli materi dan lembar validasi ahli media serta angket. Berdasarkan hasil validasi oleh ahli materi diperoleh persentase sebesar 83,30% dengan kriteria valid. Hasil validasi ahli media diperoleh persentase sebesar 83,85% dengan kriteria valid, perhitungan angket respon guru diperoleh persentase kepraktisan sebesar 97% dengan kriteria sangat praktis, perhitungan angket angket respon siswa diperoleh persentase kepraktisan sebesar 90,64% dengan kriteria sangat praktis, dan hasil posstest diperoleh persentase keefektifan sebesar 89,47% dengan kriteria efektif.
Experience of Aging in the Ngäbe‑Buglé Community in Coto Brus, Costa Rica: A Qualitative Study
Authors: Rallo Melissa , Leahy Nicholas , Vetack Alexis , Konduru Hima , Bailey Shania , Pedersen Lillianna , Wan Christine , Mora Wendel , Rowthorn Virginia , Gupta Shailvi , Faerron Guzmán Carlos
Published: January 2025

Introduction: Indigenous communities grapple with unique challenges in the aging process, often encountering amplified barriers to healthcare and resources, possibly due to their remote locations and distinct cultural backgrounds. Limited research exists on aging within Costa Rica’s Ngäbe‑Buglé Indigenous community, particularly the La Casona community in Coto Brus. This study explores the aging experience of the Ngäbe‑Buglé community in La Casona, aiming to identify challenges and potential resources to enhance the quality of life and aging experience for elderly community members.
Methods: This qualitative study utilized semi‑structured interviews to collect data from 14 elderly participants (6 female, 8 male), aged 52–90 years, living in the La Casona community. Participants were selected through purposeful snowball sampling techniques, and individual interviews were conducted at their residences. Interviews were conducted with assistance from an interpreter and lasted approximately 30–60 minutes. Thematic analysis was used to examine participants’ responses to understand their experiences with aging.
Results: Three primary themes emerged: economic difficulties, insufficient social support, and cultural aspects related to La Casona. Among the three primary themes were a total of eight subcategories. Economic challenges encompassed financial constraints and food insecurity, housing and infrastructure needs, and difficulties in accessing healthcare. Insufficient social support was evident through heavy reliance on family, limited community aid, and an absence of engaging activities. Cultural aspects highlighted the community’s deep connection to nature and concerns about the fading cultural heritage among younger generations. These themes collectively contribute to the challenges confronted by elderly adults in the Ngäbe‑Buglé community.
Conclusions: Improving healthcare access, enhancing social interactions, and preserving cultural heritage are essential when it comes to improving the aging experience in La Casona. The following participant discussions provide insight into public health interventions. Addressing these issues will require governmental support and policy changes aimed at uplifting the Ngäbe‑Buglé community.
EVANGELICALS AND ABORTION: Historical, Theological, Practical Perspectives
Authors: Charles Cleworth Charles
Published: January 2025

Book review
Perilaku Abnormal Tokoh pada Novel Kelab dalam Swalayan Karya Abi Ardianda
Authors: Saputra Rizal Abriyan Syah , Dasuki Mohammad Ramdon
Published: January 2025

Penelitian ini bertujuan untuk mendeskripsikan bentuk perilaku abnormal tokoh pada novel Kelab dalam Swalayan Karya Abi Adrianda. Penelitian ini menggunakan pendekatan psikologi sastra dengan teori psikopatologi atau psikologi abnormal dari Gerald C. Davison. Metode yang dipakai pada penelitian ini yaitu deskripsi kualitatif yang mana data akan dikelompokkan sesuai rumusan masalah lalu di deskripsikan secara sistematis agar mudah dipahami pembaca. Data pada penelitian ini ialah kutipan atau dialog yang berasal dari sumber data yaitu novel dengan judul Kelab dalam Swalayan Karya Abi Ardianda. Tahapan pembuatan penelitian ini diawali dengan membaca sumber data, mempelajari dan menelaah sumber data, dan menganalisis data sesuai dengan bantuan teori psikopatologi. Hasil pada penelitian ini didapatkan tokoh yang memiliki perilaku abnormal antara lain: tokoh Sonja, tokoh Ibu, dan tokoh Kamala. Bentuk perilaku abnormal dibagi menjadi dua bentuk besar yaitu gangguan psikologi dan gangguan rentang umur lalu di kelompokan pada sub unit masing-masing bentuk perilaku abnormal
Pengembangan Media Prezi Pada Kemampuan Menulis Teks Cerpen Kelas XI
Authors: Wahyuni Luluk Sri
Published: January 2025

Penelitian memiliki tujuan untuk merancang dan menguji validitas serta kelayakan media pembelajaran berbasis Prezi dalam meningkatkan keterampilan menulis teks cerita pendek bagi siswa kelas XI SMA. Media Prezi dipilih karena dinilai efektif dalam menarik minat siswa dan memfasilitasi lingkungan kelas yang lebih interaktif. Diharapkan, penggunaan media ini dapat membantu siswa dalam mengembangkan keterampilan menulis, khususnya dalam membuat teks cerita pendek. Proses penelitian dan pengembangan mengikuti lima tahap dalam model Dick and Carry (ADDIE), yaitu analisis, desain, pengembangan, implementasi, dan evaluasi. Data dikumpulkan melalui validasi oleh ahli media dan materi, serta melalui respon siswa. Pengujian media dilakukan di kelas XI SMA Negeri 1 Bubulan. Hasil analisis data menunjukkan bahwa media Prezi yang dirancang dianggap baik dan layak digunakan, berdasarkan penilaian ahli media, ahli materi, dan tanggapan siswa. Validasi oleh ahli media menunjukkan kelayakan sebesar 75% dengan rata-rata skor 3 dalam aspek kualitas media, sementara validasi ahli materi menunjukkan tingkat kelayakan sebesar 85% dengan rata-rata skor 3,4. Secara ilmiah, media pembelajaran ini terbukti efektif dan dapat diterapkan dalam pembelajaran, khususnya dalam keterampilan menulis teks cerita pendek
How Job Satisfaction and Organizational Commitment Affect the Organizational Citizenship Behavior of Factory Employees: The Role of Psychological Contract as a Mediator
Authors: Wibowo Ardy , Syah Toufan Aldian , Harahap Ridho Satria , Fatmasari Ayu , Nurcholis Anugrah Wing
Published: January 2025

During the increasingly heated global competition, employee performance is considered the key to success for the organization. Therefore, management must establish effective strategies and policies to stimulate and encourage increased employee performance. This study analyzes the effect of job statistics and organizational commitment on organizational citizenship behavior (OCB). The sampling method used in this research is probability sampling with a sample of 346 respondents and uses a questionnaire as a data collection method. The data analysis used is the validity and reliability of the instrument, hypothesis testing, and path analysis using the SmartPLS 4.0 program. In this study, the theoretical and managerial implications are discussed further. The results of this study indicate that job satisfaction and organizational commitment do not directly affect organizational citizenship behavior. However, the psychological contract is essential in mediating job satisfaction and organizational loyalty to organizational citizenship behavior
Study on Front Office Total Service Quality at Super- Speciality Hospitals in India - A Diagnostic Study
Authors: Natraj Anu. A. , Viswanath N.S. , Sateeshchandra Navya Gubbi , Ray Samrat
Published: January 2025

Total Service Quality (TSQ) at the front office is a critical element in every super-specialty hospital-integral to the hospital's administrative function. The backbone of its operations is a well-coordinated team of front-office executives responsible for planning, supervising, and efficiently managing hospital operations while maintaining daily coordination with all departments. As the initial point of contact for patients, these executives require continuous training and development to enhance patient happiness. Aligning training programs with high-quality service delivery is essential for improving productivity across-both the front and back ends of-the hospital, crucial for maintaining service standards. In this context, the primary aim of the study is to measure the overall service quality of the administration staff and its impact on patient satisfaction in super-specialty hospitals. The primary data was collected by an ordered random sampling without replacement method [ORSWRM] gathered from 100 respondents in Bengaluru city. The findings of the study highlights factors such as timely service delivery, adherence to prescribed treatments, complaint resolution, patient attention, and staff's communication skills are vital in realizing the hospital's vision, mission, goals, and objectives making TSQ a tangible reality.
Características do uso de antibióticos na pós-pandemia do COVID-19 no Brasil
Authors: Arrais Paulo Sérgio Dourado , Castro Lucas Frota Catunda Rodrigues de , Brandão Maria Fernanda Barros de Oliveira , Saavedra Pamela Alejandra , Dalla-Costa Ester Massae Okamoto , Silva Emília Vitória da , Luzia Vera Lúcia , Araújo Patrícia Sodré
Published: January 2025

O alto consumo e uso inadequado de antimicrobianos podem implicar no aumento da resistência aos antimicrobianos. O presente trabalho teve por objetivo analisar a prevalência do uso de antibióticos no Brasil e sua distribuição segundo aspectos sociodemográficos. Trata-se de um estudo transversal, realizado entre dezembro de 2023 e abril de 2024, com indivíduos com idade igual ou maior que 18 anos, residentes no Brasil. O método de amostragem foi o “bola de neve virtual”, iniciado com a seleção de 43 “sementes”, por todo o Brasil, que receberam convite e link do formulário para responder a pesquisa através da rede social virtual WhatsApp e depois repassaram para mais 10 pessoas de seus contatos e assim sucessivamente. Foram coletas informações demográficas, socioeconomias, sobre a utilização de antibióticos nos últimos 15 dias, motivo de uso e local de aquisição. Adicionalmente, foi realizada a categorização AWaRe (Acesso, Alerta, Reserva) dos antibióticos. Das 1.319 respostas analisadas, 13,0% fez uso de pelo menos um antibiótico. Somente a variável das faixas etárias mostrou diferença estatisticamente significante (p<0,05). Dos 203 fármacos referidos, prevaleceu a amoxicilina (23,6%) e a azitromicina (21,7%); 45,4% dos antibióticos foram de baixo potencial para causar resistência aos antimicrobianos. A maioria dos antibióticos foi indicada por médicos (66,0%), mas 25,6% praticaram a automedicação; 45,6% dos motivos de uso corresponderam a infecções das vias aéreas superiores. A maioria dos resultados encontrados foi semelhante a outros estudos de utilização de antibióticos realizados no âmbito nacional e internacional.
O sistema de abastecimento urbano: um estudo no município de Mossoró-RN
Authors: Oliveira Vera Lúcia Lopes de , Gomes Edivânia Torres de Aguiar , Costa Sérgio Luiz Freire
Published: January 2025

Este estudo aprofundou a análise da percepção da comunidade acadêmica da FACEM/UERN sobre o sistema de abastecimento de água em Mossoró-RN, buscando identificar as principais demandas e insatisfações dos usuários. Através de uma pesquisa rigorosa, envolvendo uma amostra representativa de professores, alunos e técnicos administrativos, em conjunto com entrevistas aprofundadas a gestores da CAERN, foi possível construir um panorama detalhado da situação. Os resultados obtidos evidenciaram uma divergência significativa entre as percepções dos consumidores e da empresa prestadora de serviços. Enquanto os usuários da comunidade acadêmica relataram uma série de problemas, como interrupções frequentes no fornecimento de água, baixa pressão e oscilações na qualidade da água, além de tarifas consideradas elevadas, a CAERN, por sua vez, apresentou uma visão mais otimista, afirmando que o sistema atende adequadamente à demanda e que os investimentos realizados nos últimos anos têm contribuído para a melhoria do serviço. As discrepâncias encontradas entre as percepções dos diferentes atores envolvidos ressaltam a necessidade de uma comunicação mais transparente e eficaz entre a empresa prestadora de serviços e os consumidores. Além disso, os resultados destacam a urgência de investimentos em infraestrutura para garantir um abastecimento de água contínuo, com pressão adequada e qualidade satisfatória, atendendo às necessidades da crescente população de Mossoró. A pesquisa sugere que a CAERN poderia implementar medidas como a realização de pesquisas de satisfação periódicas, a criação de canais de comunicação mais acessíveis e a participação da comunidade em processos de planejamento e gestão do sistema de abastecimento de água.
Automação do Brighton Pediatric Early Warning Score (BPEWS): treinamento, aplicabilidade e impactos na assistência hospitalar
Authors: Inoue Daiane Cristina Moderno Estevam , Inoue Luiz Hiroshi , Calzzavara Ariane Rosa Batista , Tsuneto Alessander Tieo , Silva Isabela Vanessa Tavares Cordeiro da , Batista Natany Aparecida , Theodoro Mikhael dos Santos , Porcu Mauro
Published: January 2025

A segurança do paciente é um elemento central na assistência pediátrica, especialmente em casos de deterioração clínica que demandam intervenções rápidas e assertivas. Este estudo teve como objetivo capacitar a equipe de saúde para o uso da ferramenta Brighton Pediatric Early Warning Score (BPEWS) no formato de planilha automatizada e analisar sua percepção em relação à aplicabilidade da ferramenta e impacto na prática clínica. Trata-se de um estudo quantitativo, descritivo e transversal, realizado com 12 profissionais de saúde atuantes na enfermaria pediátrica de um hospital-escola. A capacitação foi conduzida presencialmente, utilizando um site educativo para suporte teórico e acesso à planilha. A coleta de dados foi realizada por meio de um questionário estruturado baseado na escala de Likert. Os resultados indicaram a aceitação positiva da ferramenta, com todos os participantes reconhecendo sua utilidade para avaliação clínica e segurança do paciente pediátrico. A maioria destacou o treinamento como adequado e expressou confiança no uso do BPEWS automatizado. A integração de tecnologias digitais foi percebida como um facilitador para a implementação de protocolos e aprimoramento do cuidado. Conclui-se que o uso da planilha automatizada do BPEWS e a capacitação da equipe são estratégias eficazes para otimizar a prática assistencial pediátrica, promovendo maior segurança e comunicação entre a equipe multiprofissional. Recomenda-se a continuidade de programas de educação permanente e a ampliação do uso da ferramenta em diferentes contextos clínicos.
Construindo sinergias em cuidados paliativos: experiência de educação permanente na APS em um contexto amazônico
Authors: Agrizzi Lorena Miranda , Alves Raniele Alana Lima , Martins Fabiana Mânica
Published: January 2025

Este trabalho teve como objetivo relatar a experiência de construção e aplicação de atividades de Educação Permanente em Saúde (EPS) para equipes da Estratégia Saúde da Família (ESF) no município de Marabá/Pará, com foco na sensibilização sobre Cuidados Paliativos (CP) na Atenção Primária à Saúde (APS). A iniciativa buscou superar o desafio de introduzir conceitos de CP em uma região com pouco ou nenhum acesso técnico à abordagem. Trata-se de uma pesquisa-intervenção fundamentada na cartografia deleuziana, que utilizou ferramentas como diário de campo e observação-participante. Durante rodas de conversa, os participantes demonstraram uma percepção ampliada sobre CP, abordando não apenas casos de doenças oncológicas, mas também questões de saúde mental, Doenças Crônicas Não Transmissíveis e os impactos dos Determinantes Sociais da Saúde no sofrimento das pessoas. Além disso, destacou-se a relevância de expandir o entendimento sobre quem necessita de CP, proporcionando um cuidado precoce e alinhado às necessidades das populações locais. A pesquisa-intervenção reforçou a necessidade de fortalecer ações educativas no contexto amazônico, promovendo CP integrado as linhas de cuidado e atento às complexidades da APS.
Проблема доверия между гражданином и государством в условиях цифровизации: к вопросу о связи суверенитета с общением и правом на риск
Authors: Белоус В.Г. , Никифоров А.А.
Published: January 2025

Авторы статьи анализируют политику, общение и восприятие риска на примере современной России в контексте широкого спектра политико-философских идей: от Аристотеля до М. Фуко. Политика рассматривается как сфера общения и культуры. Авторов интересует, каким образом в условиях цифровой трансформации осуществляется взаимосвязь между и суверенитетом граждан, с одной стороны, и преодолением рисков – с другой. Подчёркивается, что игнорирование ценностей и перспектив внутригосударственного общения является показателем кризиса современной политики. Авторы указывают на эволюцию способов управления рисками от принятия индивидуальной ответственности к делегированию этой ответственности государству. Кроме того, рассматривается влияние цифровизации на доверие между государством и гражданами, подчёркивается важность симметричного анализа доверия как к государству, так и к гражданам. В итоге делается вывод о необходимости выработки новых практических методов анализа цифровых дискурсов для оценки доверия между государством и гражданами. Лейтмотивом статьи является поиск новых подходов к общению, управлению рисками и установлению доверия в современной политике, особенно в условиях цифровизации; данные аспекты представлены как ключевые для социокультурного развития общества.

The given article analyzes politics, communication and risk-perception in the context of contemporary Russia. Research design is based on the ideas of Aristotle, and the concept of governmentality of M. Foucault. The authors investigate the relationship between politics as an area of communication, and culture, and the sovereignty of citizens, on the other hand, the paper reflects on the role of risk in formation of civic sovereignty. It is emphasized that ignoring the values and prospects of domestic communication is an indicator of the crisis of modern politics. The authors point to the evolution of risk-management approach from taking individual responsibility to delegating this responsibility to the state. In addition, the arguing is considered the impact of digitalization on trust between the state and citizens. It is emphasized the importance of a symmetrical analysis of trust in both the state and citizens. As a result, the article reflects on the need to develop new practical methods of analyzing digital discourses to assess trust between the state and citizens. The general theme of the article is the search for a new approaches to communication, risk management and building trust in modern politics, especially in the context of digitalization, that presents such important aspects of socio-cultural development of society.
Построение идентичности в межкультурных взаимодействиях
Authors: Корякина А.А.
Published: January 2025

Данная научная работа посвящена проблеме построения идентичности в контексте межкультурных взаимодействий. Идентичность является актуальной сферой исследования в социальной философии, и взаимодействие между различными культурами может существенно влиять на формирование и переосмысление личностной и коллективной идентичности. Автором исследованы основные подходы, влияющие на построение идентичности в межкультурной среде. Цель – изучение процесса построения идентичности в контексте межкультурных взаимодействий с позиций этих подходов. В статье представлены и сопоставлены постструктуралистский и гуманистический подходы к исследованию идентичности в межкультурной коммуникации, используемые исследователями. Показано, на каком основании люди конструируют идентичность других и как люди реагируют на несоответствие между тем, как они себя идентифицируют, и тем, как их воспринимают. Согласно постструктуралистской традиции, предлагается модель межкультурной коммуникации, применимая в полиэтнических обществах. Модель рассматривает процесс коммуникации с позиции человека. Согласно гуманистическому подходу, показано, насколько актуально конструировать идентичность другого человека в соответствии с его самоидентификацией в конкретный момент.

This scientific work is devoted to the problem of identity construction in the context of intercultural interactions. Identity is an actual field of study in social philosophy, and interactions between different cultures can significantly influence the formation and redefinition of personal and collective identities. The article studies the main approaches that influence the construction of identity in an intercultural environment. The purpose of the article is to study the process of identity construction in the context of intercultural interactions from the perspective of these approaches. The article presents and compares poststructuralist and humanistic approaches to the study of identity in intercultural communication used by researchers. The article shows how people construct the identities of others and how people respond to discrepancies between how they identify and how they are perceived. According to the poststructuralist tradition, a model of intercultural communication is proposed that is applicable in multiethnic societies. The model considers the communication process from a human perspective. According to the humanistic approach, it is shown how relevant it is to construct the identity of another person in accordance with his self-identification at a particular moment.
Феноменология чистого музыкального бытия А. Ф. Лосева
Authors: Бочаркин Д.В. , Матюшова М.П.
Published: January 2025

Феноменологический подход к изучению видов искусств имеет свои особенности, которые складываются с момента появления данного направления. Феноменология интересуется музыкой в большей степени в силу её абстрактности, ведь несмотря на то, что она не имеет материальной формы, как скульптура, живопись или архитектура, музыка так или иначе крайне сильно способна влиять на психоэмоциональное состояние человека. Может показаться, что именно физиология, психология и физика должны быть основой подобных исследований, однако, как показывает А. Ф. Лосев в работе «Музыка как предмет логики», данная база не может в полной мере объяснить феномен подлинной музыки. Чтобы постигнуть или как минимум прикоснуться к настоящему феномену музыки, мыслитель вводит понятие «чистое музыкальное бытие», которое имеет свои основные положения. Целью статьи является рассмотреть и проанализировать предложенный А. Ф. Лосевым концепт чистого музыкального бытия в своей специфике и структурности. Исследуя основоположения по А. Ф. Лосеву, формируется вывод, что чистое музыкальное бытие есть бытие гилетическое, проявляющееся в хаотичной форме; музыка представляет собой борьбу с самостью, но имеет в себе жизнь чисел, отсюда и становится очевидной опора философа на античную идею связи математики с музыкой, однако мыслитель наделяет первое логичностью, а второе – алогичностью.

Phenomenological approach to the study of arts has its own peculiarities, which have formed since the emergence of this direction in philosophy. Phenomenology is interested in music to a greater extent due to its abstract nature; although it does not have a material form like sculpture, painting or architecture, music is extremely capable of influencing the psycho-emotional state of a person. It may seem that physiology, psychology and physics should be the basis of such studies, but, as A. F. Losev shows in his work “Music as a Subject of Logic”, this basis cannot fully explain the phenomenon of real, authentic music. In order to comprehend or, at least, to touch the real phenomenon of music, the thinker introduces the concept of “pure musical existence”, which, in turn, has its own basic provisions. The aim of the article is to examine and analyse the concept of pure musical existence proposed by A. F. Losev in its specificity and structure. By examining the fundamentals, according to A. F. Losev, a conclusion is formed that pure musical existence is a hyletic being, manifesting itself in a chaotic form; music is a struggle with selfhood, but has in itself the life of numbers, hence the philosopher's reliance on the ancient idea of the connection between mathematics and music becomes obvious, but A. F. Losev endows the former with logicality and the latter with illogicality.
Aspects of increasing productivity of soft spring wheat in the northern forest-steppe
Authors: Yula  V.M. , Drozd M.O.
Published: January 2025

The purpose of the research is to study the agrotechnological aspects of increasing the producti­vity of soft spring wheat in the conditions of the Northern Forest-Steppe of Ukraine in the context of climate change. Research is aimed at optimizing spring wheat cultivation technology based on the use of modern fertilization systems, growth stimulants and plant protection agents. Special attention is paid to determining the influence of growing conditions on the productivity of spring wheat and adapting agrotechnological techniques to ensure stable and high yields of this crop under climate changes. Methods. The research program included the following methods: field, biometric and measuring-weighing, laboratory, comparative-calculating, as well as mathematical-statistical. Results. It was established that for the cultivation technology, which provided for the treatment of seeds with an organic fertilizer with a stimulating effect, the application of N45P90K90 before sowing and for N45 at the 30th and 48th stages of development according to ВВСН against the background of earning by-products of the predecessor and the application of integrated crop protection on average for 2021−2023 obtained the highest yield of soft spring wheat at the level of 4.35 t/ha. The yield increase for this technology compared to the control was 1.80 t/ha. The complex application of elements of the technology of growing soft spring wheat affected both the yield and quality indicators of the grain. In particular, the content of crude protein was 15.15%, crude gluten – 25.31%, which corresponds to the first quality class in accordance with the requirements of DSTU 3768:2019. Conclusions. It was established that mineral fertilizers, plant growth stimulators, crop protection systems and by-products of precursors are integral components in the technology of growing soft spring wheat. On average, for 2021−2023, the effect of using mineral fertilizers was 0.18−1.80 t/ha, depending on the level of fertilization and the crop protection system. Optimization of nutrition, in particular, the introduction of mineral and organic fertilizers with a stimulating effect, helps plants to adapt to stressful conditions, increasing their productivity under changing climatic conditions.
The main diseases of spring wheat and the use of biofungicides in the northern Forest-Steppe of Ukraine
Authors: Raichuk T.M.
Published: January 2025

The purpose of the research was to identify the most common diseases of spring wheat grown in the Northern Forest-Steppe and to identify the most effective biological products used in the experiment against diseases of spring wheat. Methods. The experimental studies were conducted during 2021–2024 in the Northern Forest-Steppe in the field experiments of the Plant Protection Department of the National Research Center “Institute of Agriculture NAAS” in Chabany village, Fastiv district, Kyiv region. Object of research: spring wheat variety Rannіa 93. Weather conditions during the years of research contributed to the development of diseases. Results. As a result of the crops’ inspections, the following diseases were detected: powdery mildew (Blumeria grumines (DC.) Speer. (BLUMGR), leaf septoria (Septoria trittici Roberge ex Desm. (SEPTTR), ear blight (Sertoria nodorum (Berk.) Berk (SEPTNO), pyrenophora tritici-repentis (Died.) Drechsler and root rot (Fusarium (FUSASP), Bipolaris sorokiniana (Sacc.) Shoemaker (BIPOSO), Gaeumannomyces graminis (Sacc.) Arx & L.L.Olivier (GAEUGR), Pseudocercosporella herpotrichoides (Fron) Deighton (PSEUHE), Alternaria spp. ) (ALT), Fusarium spp. (FUSASP), brown rust Puccinia recondita f. sp. tritici Rob. ex Desm (P. triticina Erikss). Conclusions. The growing seasons of 2021–2024 were favorable for the development of wheat diseases, but the effectiveness of biological products during the spring wheat growing season was low and at the end of the growing season was less than 30%. The surveys conducted after three treatments showed that there is no significant effectiveness in relation to the control in variants with the use of different biological products based on different active ingredients. When applying biological products during the growing season, spring wheat yielded 0.1-0.9 t/ha more than in the control. The highest yield increase was in the variant with the use of a mixture of Sporazin 2 l/ha + Phytophyt 0.05 l/ha + Biostimix 0.5 l/ha + Xampan 0.25 l/ha, Sporomax T 1- 2 kg/ha + Sporomax B 2 kg/ha + Xampan 0.25 l/ha. Thus, the preserved yield indicates that the treatment of spring wheat crops with biological products has a positive effect on plants. Therefore, the use of biofungicides in the protection of spring wheat requires further research, and the study of the protection problem remains relevant.
A ten-year retrospective on the efficacy of droplet vitrification for cryobanking of Allium ramosum L. germplasm
Authors: Chander Subhash , Gowthami Ravi , Pandey Ruchira , Deepak DA , Agrawal Anuradha
Published: January 2025

BACKGROUND: Allium ramosum is an important member of the genus Allium, which is commonly known as Chinese chive or fragrant-flowered garlic. Conserving the genetic diversity of different species of Allium is crucial, and cryopreservation has emerged as an
important strategy for long-term conservation of alliums. OBJECTIVE: To develop a reliable protocol for the cryoconservation of A. ramosum shoot bases. MATERIALS AND METHODS: Different parameters, viz. (a) coldhardening (5°C for 16/8 h photoperiod), (b)
PVS2 dehydration (0, 5, 10, 15, 20, 25, 30, 35, 40, 45, 50, 55 and 60 min), (c) pregrowth medium (MM3: MS + 0.1 mg/L NAA + 0.5 mg/L 2iP + 10 mg/L spermidine + 3% sucrose; MM10: MS + 0.1 mg/L NAA + 0.5 mg/l 2iP + 10 mg/L spermidine
+ 10% sucrose) and (d) preculture duration (1, 2, 3, 4 and 5 days) were tested using a vitrification technique. RESULTS: Shoot bases excised from 4-wk old in vitro cultures that had been cold-hardened at 5°C (16/8 h photoperiod) and precultured on MM10 with 10%
sucrose at 5°C for 3 days resulted in highest post-thaw regrowth of 43% after conventional vitrification. However, when droplet-vitrification was used, post-thaw regrowth was increased to 77%. Retesting of shoot bases after 10 years of cryobanking, revealed no significant
difference in the post-thaw regrowth of A. ramosum. CONCLUSION: This is the first report of the long-term cryopreservation of A. ramosum shoot bases using vitrification and droplet-vitrification techniques.
Fortification of semen extender with mifepristone improves the cryo-survival of cattle spermatozoa
Authors: Kumar Arun , Sachan Vikas , Anand Mukul , Kumar Anuj , Chaudhary Neha , Singh Garima , Kumar Mohit , Kumar Agrawal Jitendra , Saxena Atul
Published: January 2025

BACKGROUND: Progesterone, which is present in the semen extender as a component of egg yolk is a potential inducer of capacitation in spermatozoa during cryopreservation. An anti-progesterone component in the extender may protect the spermatozoa from being capacitated and pre-acrosome
reacted during cryopreservation. It may lead to better quality of post-thaw sperm population for improved conception. OBJECTIVE: To investigate the effect of mifepristone on the cryo-survivability of cattle spermatozoa. MATERIALS AND METHODS: Thirty two semen ejaculates were
collected from four Sahiwal bulls and divided into three fractions. These fractions were extended with egg yolk-based TRIS extender supplemented with different concentrations of mifepristone (0, 10 and 20 μM) and subjected to cryopreservation. Cryopreserved semen samples were thawed and
evaluated for spermatozoa motion parameters (CASA), viability (flow cytometer), hypo-osmotic swelling test (HOST) responsiveness, capacitation status (CTC), acrosome reaction (flow cytometer) and intracellular calcium ion concentrations (flow cytometer). RESULTS: There was no definitive
effect of mifepristone on sperm motility and kinematics. However, the semen samples which were treated with mifepristone showed significantly higher spermatozoa viability and HOST responsiveness. Mifepristone also protected spermatozoa from being cryo-capacitated during the preservation process.
Higher percentages of uncapacitated and acrosome intact spermatozoa were found at the post-thaw stage in comparison to the untreated group. Mifepristone-treated groups showed fewer spermatozoa with high intracellular calcium levels. CONCLUSION: A 10 μM concentration of mifepristone
has better potential to protect the spermatozoa from progesterone-induced cryo-capacitation and premature acrosome reaction during cryopreservation.
Low-dose LPS and calorie restriction combined therapy for pancreatic ductal adenocarcinoma: an in vitro and in vivo study
Authors: Beydogan Bahar , Işıldar Başak , Coşkun Yazıcı Zeynep Mine , Koyutürk Meral , Bolkent Sema
Published: January 2025

Objective: This study aimed to evaluate the therapeutic effects of lipopolysaccharide (LPS) on Panc02 cells since LPS is an inflammatory
agent with the potential to activate the immune system and reorganize the tumor microenvironment. Moreover, calorie restriction
(CR) has been investigated in combination with LPS as a prospective adjuvant intervention for cancer therapy.
Materials and Methods: Panc02 cells were cultured in two distinct media with low and high-glucose concentrations, and cell viability
was investigated after applying varying doses of LPS to culture media. The in vivo effects of LPS and CR were investigated on the mice
subcutaneous pancreatic ductal adenocarcinoma (PDAC) tumor model in terms of tumor mass, histological examination, mRNA
expression profiles, and biochemical parameters.
Results: The lowest cell count was detected in the cells treated with 10 μg/ml LPS in low-glucose environments in vivo. Tumor mass
significantly decreased in the P+LPS+CR group in vivo. The mRNA expression analysis of tumor tissues indicated that P+LPS+CR acts
through NF-κB, JNK, and IL-6 signaling pathways.
Conclusion: Lipopolysaccharide alone is insufficient to show therapeutic effects, but it can inhibit tumor development by acting on
NF-κB and JNK pathways when combined with CR. This study gives insight into developing new treatment options for PDAC.
Vitamin D3 has antifibrotic effects on rats with epidural fibrosis
Authors: Kuru Bektaşoğlu Pınar , Hazneci Jülide , Somay Adnan , Börekci Ali , Gürer Bora
Published: January 2025

Objective: One unfavorable outcome of spinal operations is epidural fibrosis. Recurrent back pain and radiculopathy could negatively
impact the patient’s quality of life. In this study, using a rat laminectomy model, we sought to examine any potential antifibrotic
benefits of vitamin D3.
Patients and Methods: Control, local, and systemic vitamin D3 groups (n = 6 rats per group) were randomly assigned. Laminectomy
alone was carried out in the control group. Vitamin D3 application onto the dura was done in the local D3 group. Intraperitoneal
delivery of the systemic vitamin D3 was carried out in the systemic vitamin D3 group. Epidural fibrosis was studied macroscopically
and histopathologically four weeks later.
Results: The macroscopic epidural fibrosis score was lower in the local and systemic vitamin D3 groups compared to the control
group (p