bluuebunny/crossref_metadata_2025 huggingface dataset:
ВПЛИВ ПОДВІЙНОЇ АНТИТРОМБОТИЧНОЇ ТЕРАПІЇ НА ПОКАЗНИКИ ТРОМБОЦИТАРНОГО ГЕМОСТАЗУ У ПАЦІЄНТІВ З ІХС
Authors: Козачишин Н.І. , Нетяженко В.З. , Плєнова О.М.
Published: June 2023

Ішемічна хвороба серця була, є і залишається однією із основних причин смертності та інвалідності серед людей старших вікових груп. Завдяки імплементації сучасних методів лікування є висока ймовірність усунення небажаних наслідків ішемічних подій. Стратегії реваскуляризації дозволяють подовжити життя пацієнтів, тим самим протидіючи виникненню повторних гострих коронарних синдромів, про що свідчать численні рандомізовані клінічні дослідження [1,2]. Окрім інструментальних методів, важливе місце має правильна фармакотерапія. Застосування антиагреантів є ключовим для лікування та профілактики як місцевих, так і системних тромботичних ускладнень [3,4]. Згідно з останніми рекомендаціями ESC, в нашому арсеналі є більш потужні інгібітори P2Y12, такі як тікагрелор або прасугрель. [5,6]. Однак, не завжди дані препарати доцільні у використанні. Краще розуміння ризику виникнення ішемії та кровотечі, а також індивідуальної чутливості до антиагрегантів, відіграло важливу роль у визначенні оптимального режиму для окремого пацієнта. Інтегрований підхід, включаючи шкали для груп ризику, процедурні характеристики та інструменти, допомагають оцінити відповідь на ліки, що є найбільш перспективним підходом для персоналізованого вибору антиагрегантів серед пацієнтів, які проходять черезшкірне коронарне втручання (ЧКВ). [7].
ОСОБЛИВОСТІ ТЕЛЕПРОГРАМ ДЛЯ ЕТНІЧНИХ СПІЛЬНОТ ЗАКАРПАТТЯ ПЕРІОДУ ПОВНОМАСШТАБНОЇ ВІЙНИ
Authors: Толочко Наталія
Published: June 2023

Національний медіаринок зазнав суттєвих змін в умовах повномасштабної російсько-української війни: стрімко збільшуються обсяги контенту, використовуються нові формати; скорочується аудиторія традиційних медіа; зменшуються обсяги рекламного ринку; редакції проживають кризові періоди тощо. Крім цього, українська медіасистема поступово трансформується на шляху вступу нашої держави до ЄС, у мовах застосування нових законів «Про медіа», «Про національні меншини (спільноти) України». Серед іншого, приділяється увага мові ЗМІ, забезпеченню прав етносів, у тому числі права на інформацію.
ТЕОРЕТИКО-МЕТОДИЧНІ АСПЕКТИ ДОСЛІДЖЕННЯ РЕЧЕНЬ В СУЧАСНОМУ МОВОЗНАВСТВІ
Authors: Поляк Ірина , Медвідь Лілія
Published: June 2023

Сучасне вивчення речення покликане утвердити його центральну роль в граматичній системі сучасної української літературної мови та виділити його важливе місце у формуванні та вираженні думки мовця.

Дослідниця Н. Бондаренко у науковій розвідці «Лінгвістичні засади компетентнісної методики навчання синтаксису» зазначає, що «мовознавці розглядають речення як складне, багатоаспектне й різнопланове утворення в усій багатовимірності його складників, що об’єднують і увінчують всі аспекти, рівні та яруси мовної системи. Це цілком відповідає традиційній для закладу загальної середньої освіти орієнтації на різні аспекти розгляду – мовних явищ. Водночас науковці зосереджуються на основному об’єкті – мовленні в усьому багатстві й розмаїтті його конструктивних можливостей, семантичних (смислових) і стилістичних варіантів, паралельних і синонімічних побудов» [1, с. 12].
ТЕНДЕНЦІЇ РОДОВОЇ ДИФЕРЕНЦІАЦІЇ ІМЕННИКІВ У СУЧАСНІЙ УКРАЇНСЬКІЙ ЛІТЕРАТУРНІЙ МОВІ
Authors: Поляк Ірина , Ариванюк Анастасія
Published: June 2023

Однією з актуальних проблем сучасної української літературної мови є родова диференціація іменників. Сьогодення вимагає розгляду питань становлення, статусу та правильного трактування граматичної категорії роду українських іменників. Поняття «категорія роду» в процесі історичного формування набуло чимало самобутніх рис, які відрізняють українську мову від інших. Мовознавець І. Г. Матвіяс наголошує на тому, що ««рід» має статут лексико-граматичної категорії, яка відображена у формах жіночого, чоловічого та середнього роду» [1, с. 50]. Інші лінгвісти мають дещо іншу думку стосовно родової диференціації іменників, і розглядають її як «відношення між узгоджуваним і узгоджуючим словом». Існують різні теорії щодо виникнення цієї лексико-граматичної категорії, зокрема це відображено в історичних граматиках. Проте й досі науковці не можуть розв’язати цього питання.
ВИКОРИСТАННЯ ЕЛЕМЕНТІВ STEM-ОСВІТИ В СИСТЕМІ ПІДГОТОВКИ МАЙБУТНІХ УЧИТЕЛІВ ПОЧАТКОВИХ КЛАСІВ
Authors: Молнар Т. І.
Published: June 2023

Сучасне інформаційне суспільство висуває нові вимоги до вищої педагогічної освіти, яка покликана забезпечити формування у майбутніх учителів початкових класів важливих професійних компетентностей, що дозволять успішно соціалізуватися в майбутньому.

Сьогодні в таких країнах, як Австралія, Великобританія, Ізраїль, Канада, Китай, США та ін. стає популярною STEM-освіта, концепція якої передбачає включення у свою структуру творчих дисциплін, які не тільки збагачують зміст освіти, а й значно підвищують якість підготовки майбутніх фахівців. Інтеграція науково-технічної та творчої (гуманітарної) областей покращує результативність освітнього процесу. Разом з тим, активна робота обох півкуль мозку забезпечує розвиток як логічного (ліва півкуля), так і інтуїтивного, креативного (права півкуля) мислення.
ОСВІТНІ ЦІННОСТІ В УМОВАХ МОДЕРНІЗАЦІЇ ОСВІТИ
Authors: Жукова Г. В. , Булгакова Т. М.
Published: June 2023

У сучасному світі відбувається поступова зміна уявлень про те, як людина повинна отримувати освіту. Основною стає ідея безперервної освіти, згідно якої активно діючий член соціуму повинен вчитися все життя. Частка неформального навчання в системі освітніх послуг постійно збільшується. Незважаючи на зовнішнє протиставлення, формальні і неформальні системи навчання не суперечать, а швидше взаємодоповнюють один одного. Формальне навчання інколи критикують за відставання від практичних потреб. Неформальна освіта націлена, перш за все, на задоволення потреб особистості в професійному зростанні. В її основі лежать гуманістичні ідеї педагогіки співробітництва викладача і учня з акцентом на активну роль учня в організації процесу навчання. У формальному навчанні керуються існуючими загальновизнаними стандартами, а в неформальному – створюють свої стандарти навчання на основі наявного досвіду. Неформальне навчання є творчою лабораторією по апробуванню інноваційних методів і форм навчання.
АКТУАЛЬНІСТЬ НАВЧАННЯ ОСНОВАМ ТЕЛЕМЕДИЦИНИ НА ЕТАПІ ПІСЛЯДИПЛОМНОЇ ОСВІТИ ЛІКАРІВ-ДЕРМАТОВЕНЕРОЛОГІВ
Authors: Ніточко О.І. , Гоцуляк О.Л.
Published: June 2023

Після вторгнення російських військ в Україну, велика кількість людей почала стикатися як з психологічними, так і з фізичними проблемами зі здоров’ям. Постійне емоційне напруження, переживання за себе та близьких, вимушене переселення – усе це виступає тригером для загострення хронічних дерматозів, в першу чергу псоріазу та атопічного дерматиту. В зв’язку з вимушеним переміщенням більшість дерматологічних пацієнтів втратили доступ до звичної медичної допомоги. Тому багато українських дерматологів почали масово консультувати онлайн своїх пацієнтів. Завдяки візуальному характеру дерматологічної спеціальності, наявності нових технологій, мобільних додатків, які дають можливість отримати якісну зорову інформацію, телемедицина стає додатковим надійним інструментом, який дозволяє поставити правильний діагноз і призначити відповідне лікування у більшості випадків, що є дуже важливим в умовах воєнного часу, коли доступ до очних консультацій лікаря є обмеженим. Проте при телемедичних консультаціях ефективність лікування хворих залишається нижчою у порівнянні з класичними медичними консультаціями, особливо коли мова йде про хронічні дерматози. В першу чергу це пов’язано з низькою прихильністю пацієнтів до лікування, як наслідок відсутності прямого спілкування пацієнта з лікарем, особливо, коли хворий вперше отримує консультацію в цього лікаря і не повністю довіряє йому. Крім того на прихильність пацієнта до лікування значний вплив мають стрес, депресивні стани, тривожність, що напряму пов’язано з війною.
УКРАЇНА НА ШЛЯХУ ДО ЄВРОПЕЙСЬКОГО СОЮЗУ: ВИКЛИКИ ВІЙНИ ТА ЗАПРОВАДЖЕННЯ РЕФОРМ (НА ПРИКЛАДІ МИТНОЇ РЕФОРМИ)
Authors: Джуган Руслана Іванівна , Джуган Володимир Васильович
Published: June 2023

Україна ставши кандидатом на членство у Європейському Союзі 23 червня 2022 року повинна виконати певні вимоги – критерії та успішно провести чергову низку реформ. Аналізуючи шлях України у реалізації Угоди про асоціацію України – ЄС (з 27 червня 2014 р.) констатуємо очевидні успіхи. Серед успішних запроваджених реформ на даний час варто відмітити: децентралізації, освітньої (НУШ), медичної та ін.

Аналізуючи послідовність кроків нашої держави до вступу у ЄС, ми знаходимось на перед останньому 4 етапі, а саме отриманні статусу кандидата в члени ЄС. Успішними вважатимемо кроки: підписання Угоди про асоціацію; включення в офіційну програму розширення ЄС; подача заявки на вступ.
Building the world’s greatest school leadership curriculum: Transform your school from the inside out
Authors: White Guy
Published: June 2023

Building the World’s Greatest School Leadership Curriculum strives to make you and your school leadership team more able to transform from the inside out. This fifty-four-lesson curriculum is designed to help educator leadership teams and student leadership teams in higher education, high school, and middle school create a culture of significance where everyone at your school matters. Inside, you will find: (a) A complete 54-lesson leadership curriculum that can be delivered over the course of a whole school year, a single semester, and single/multi-day leadership workshops; (b) Robust lesson plans aligned to Common Core State Standards.- Invigorating whole-class, small-group, and single-participant exercises; (c) Thought- and emotion-provoking, supporting worksheet-based activities. (d) A one-stop solution for school and district directors, principals, assistant principals, coordinators, advisors, and activities directors who want to employ a powerful sequence of lessons and activities to bolster the work of their school. Using the activities found herein, you will be more able to… (1) Develop a decisive, impactful vision and roadmap toward your school’s ultimate culture and climate, student engagement, and parent involvement. (2) Build and carry out your plans to support student achievement and outcomes. (3) Work as a school family toward a common vision with clear expectations and accountability. Based upon the Building the World’s Greatest High School book series.
The dissertation warrior: The ultimate guide to being the kind of person who finishes a doctoral dissertation or thesis
Authors: White Guy
Published: June 2023

Don’t read this book if you want a quick and dirty way to finish your dissertation or thesis, write it in a weekend, or pay someone else to write it for you. This book is for the doctoral student who wants to become the best version of himself or herself; whose doctoral journey is a quest of epic personal, professional, and spiritual transformation; and who wants to finish his or her dissertation as well.Inside this book, you’ll learn, among many other things: (a) The secrets of time travel; (b) That 99% of that which gets your focus is not worth your time; (c) That “writing” your dissertation is the last thing that you should do; and (d) How to conquer your introduction, create alignment, build the best darned literature review you possibly can, find and collect your data, and connect all the clues better than a hat-wearing movie archeologist...all while becoming a better spouse, sibling, child of your parents, and man (or woman) of all seasons. This book is written by me, Dr. Guy. I teach, at the time of writing this book, the world’s most comprehensive online step-by-step dissertation writing course. Through my online training videos, The Dissertation Mentor® Accelerator Program, The Dissertation Mentor® Home Study Course, and The Dissertation Mentor® One-To-One Mentorship, I have helped thousands of doctoral students make progress in their dissertations. I can probably help you too! This book is my manifesto about all things “doctoral.”
Building the world’s greatest high school student leader: Creating a culture of significance where everyone matters
Authors: White Guy
Published: June 2023

You don’t have to wait until graduation to start the life of your dreams. You have the power to transform yourself and your school and have the good life today: By becoming your World’s Greatest Me and by assisting others to do the same. This book is the ultimate guide for student leaders and aspiring visionaries.Inside this book, you'll learn how to... (a) Get the good life today: no waiting for others; no waiting on life. (b) Become your World’s Greatest Me and shock the naysayers. (c) Take charge of your class and school, end boredom, and save the world. (d) Make everybody a “somebody” and (practically) stop bullying. (e) Become a test and quiz master and unlock the secrets of “time travel.” Using these fundamental skills, you will also learn how to… (1) Build the World’s Greatest High School celebrations and rallies; (2) Outsmart your leadership teacher, administrator, or advisor and build the World’s Greatest High School student leadership with other students; (3) Make your dreams (and the dreams of your classmates, teachers, and administrators) come true.Based upon the book Building the World’s Greatest High School.
Meaning and learning fractions: analysis of learning barriers from a mathematics teacher's perspective
Authors: Alsulami Naif Mastoor , Isnawan Muhamad Galang , Bahri Samsul , Pakhrurrozi Imam , Santosa Farah Heniati
Published: June 2023

Converting mixed numbers into common fractions is one of the formula problems in learning fractions which is a problem in learning. However, not many studies have examined this conversion. In addition, there are not many studies that try to provide solutions to the conversion problem. Therefore, this study aims to identify the types of learning barriers students experience when converting mixed numbers into common fractions and provide alternative solutions to minimize these learning barriers. The research design used to achieve this goal is didactical design research (DDR). DDR was chosen because it uses the results of identifying types of learning barriers to develop didactic designs in learning fractions. The participants in this study were math teachers with 26 years of age and less than 5 years of teaching experience. The main instrument in this study was the researcher using several additional instruments, such as fraction comprehension tests, interview guides, and didactic designs. The data was then analyzed using qualitative data analysis. The results of the study revealed that students indicated that they experienced learning difficulties with different types of epistemological obstacles because they rarely start learning with everyday life problems. The solution offered in the didactical design is the use of the problem as an initial situation in learning which students will then respond to in the form of a didactical situation. The recommendations offered in this study are the implementation of the didactic design itself.
Student challenges completing the matrix material story question
Authors: Nandang Nandang , Taufan Mochammad , Noviana Najwa
Published: June 2023

This study aims to determine the difficulties faced by students in solving the matrix material story problem and the factors causing it. This study used a qualitative approach with research subjects in class XI, which consisted of three female students. Determination of research subjects using a purposive sample technique. Data collection techniques in this study used observation, interviews, documentation in the form of pictures and videos, and field notes. The results of this research are the difficulties faced by students in solving the matrix material story problems, namely: the steps for solving problems according to Polya, the material matrix, and the time. Factors that cause students difficulty in solving the matrix material story problems, namely: (1) students are not accustomed to using Polya's steps, (2) not writing stages 1 to 4 of Polya's steps because they are still confused about the placement of the stages, (3) not writing the explanations in the second stage, namely problem-solving planning, (4) not writing the fourth stage, which is checking the results again or verification, (5) students still have not mastered the matrix material because their learning has been using online or online, (6) calculation errors, (7) time in working on story problems with limited matrix material due to nourishing learning during the Covid-19 pandemic.
Unworlding in Nameless
Authors: Christiansen Steen Ledet
Published: June 2023

World-building has thrived as a new field for scholars interested in fantastic fiction since it allows for new insights into how imaginary worlds are actualized other than simply the formal devices that render fantastical worlds different from non-fantastical ones. However, there are things that cannot be told and there are things that should not be told — these are the reaches that much weird fiction likes to explore. In the vocabulary of world-building, we would say that readers are never given access to a fully coherent and consistent imaginary world. The process of Nameless is what I identify as the process of unworlding — when the imaginary world is filled with contradictions and impossibilities and break any attempt at constructing a system or structure.
Transmedia Worldbuilding and Mashup Mythology in Penny Dreadful
Authors: Albertsen Anita Bech
Published: June 2023

By focusing on the merged and interfigural nature of the characters and mythology in the Penny Dreadful transmedia world, this article seeks to demonstrate that transmedia characters are essential to transmedia worlds; they are anchors from which plots and mythology develop and expand. This is contrary to what is proposed by, for instance, Susana Tosca and Lisbeth Klastrup in earlier versions of their transmedial world theory, where character in their own formulation were “subsumed under the category of mythos” (Tosca & Klastrup 2020, 37). Instead, this article argues for the opposite scenario, that the construction of mythology in Penny Dreadful’s transmedia world is intricately tied to specific mythic plot structures, defining character conflicts, character narrators, and to serialized character development as well as character elaboration across media.
Did Covid 19 disease increase mesenteric ischemia cases?
Authors: GENÇ Hüsnü Çağrı , GEMİCİ Kazım
Published: June 2023

İntroduction

Covid 19 (C19) disease causes mortal complications due to both respiratory system involvement and extrapulmonary involvement. C19 patients may present with gastrointestinal symptoms such as nausea-vomiting, diarrhea and loss of appetite, as well as serious conditions such as acute mesenteric ischemia. C19 disease is a proinflammatory condition that causes thrombus formation.

Material method

The first group (G1) was treated with 21 mesenteric ischemia cases operated in the General Surgery Department of Aksaray Training and Research Hospital in approximately two years between March 2020 and February 2022, and the second group (G2), in a two-year period between 2018-2020 before the pandemic, in the same department. The information of 11 mesenteric ischemia cases who underwent surgery were analyzed from the hospital information system. Statistically, the predisposing diseases, demographic data, intestinal lengths removed during the operation, and survival of the patients in both groups were compared.

Results

When the number of patients who were operated on in G1 and G2 were compared, it was seen that more patients were operated in G1. The probability of mesenteric ischemia in a 24-month period was found to be 0.875 in G1 and 0.458 in G2. These rates were statistically different (p=0.002). When the mean age, length of the removed bowel, and postoperative mortality of both groups were compared, no significant difference was found.

Conclusion

Although the exact mechanism by which the Covid 19 disease causes mesenteric ischemia is not understood, we observed a statistically significant increase in mesenteric ischemia cases during the pandemic period compared to the pre-pandemic return. Considering the Physiopathology of C19, it is known that the diseases in the body generally occur on the basis of vasculitis. When C19 infection is detected, we recommend anticoagulant treatment for at least 3 months during the infection and for the prevention of other complications related to vasculitis, especially mesenteric ischemia.
The predictive role of CA- 125 value in early stage endometrioid endometrial cancer
Authors: KURT Begüm , KÜÇÜKYILDIZ İrem , YANIK Ali
Published: June 2023

Objective: We aimed to evaluate the prognostic role of preoperative serum cancer antigen 125 (CA-125) in endometrioid endometrial cancer for determining the cut-off values for clinicopathological factors.

Study design: 161 patients were included in the study. The inclusion criteria were histopathological confirmation of endometrioid endometrial cancer and patients with CA-125 levels measured at most ten days before surgery. The association between CA-125 value and clinicopathological variables were analyzed. Receiver operating characteristic curve statistical tests with clinicopathological factors were used to determine the cut-off values and the prognostic role of CA-125.

Results: The median value of CA-125 level was 15.4 (3, 2-577) IU/L. These CA-125 cut-off values ranged from 14.30 to 18.67 IU/L (sensitivity 53%– 100%, specificity 30%–59%). The statistical analysis showed a significant relation between CA-125 value and stage and pelvic-paraaortic lymph nodes metastasis. The average life expectancy of patients with CA-125 ≥15.4 was 102.8±5.9 months, whereas that of patients with CA-125
Enhanced Anticancer Effect of Temozolomide through Synergistic Combination with Diltiazem in Neuroblastoma (SH-SY5Y) Cell Line
Authors: KARADEMİR Mustafa , SURARDAMAR Saime
Published: June 2023

Objective: This study aimed to assess the enhanced anticancer effect of Temozolomide (TMZ) through a synergistic combination with Diltiazem (DTZ) in the neuroblastoma cell line (SH-SY5Y).

Material and Methods: The SH-SY5Y neuroblastoma cell line was cultured in a DMEM medium. TMZ and DTZ stock solutions were prepared and diluted to obtain different concentrations. The XTT assay was performed to evaluate cell viability. Cells were treated with TMZ alone or with DTZ for 24 and 48 hours. Viability was measured using the XTT-formazan product, and statistical analysis was performed.

Results: The viability of neuroblastoma cells treated with TMZ alone and TMZ+DTZ combination was assessed. At 24 hours, TMZ showed no cytotoxic effect, while DTZ showed a low cytotoxic impact. At 48 hours, TMZ and TMZ+DTZ combination exhibited significant cytotoxic effects. The cytotoxic effects were concentration-dependent and time-dependent. DTZ alone showed significant cytotoxic effects on neuroblastoma cells at specific concentrations.

Conclusion: The study demonstrated that TMZ alone and combined with DTZ had a significant cytotoxic effect on neuroblastoma cells. The combination of TMZ and DTZ may enhance the anticancer effect of TMZ and overcome drug resistance in neuroblastoma treatment. DTZ, a P-glycoprotein inhibitor, could prevent the efflux of TMZ from cancer cells, increasing its concentration and effectiveness.
Fanonian analysis of racism and postcolonial structures of othering
Authors: Mirončuka Kitija
Published: June 2023

The paper explores how boundaries affect the search for identity in the context of racism and colonialism. Colonized individuals often experience a sense of alienation and inferiority caused by the limitations imposed by colonial power structures, leading to a quest for personal identity. However, the binary division between the colonizer and colonized affects everyone involved, making searching for personal identity more complex and reinforcing systemic racism. The first section of the article examines how race, a socially constructed concept, plays a crucial role in defining the difference between oneself and others, imposing structures of othering based on Fanonian analysis. The second section discusses whether it is possible to avoid or overcome racism and racial oppression, shedding light on the inherent nature of othering, racism, and latent violence.
Identification of Citrobacter freundii from Skin Wounds in Goldfish (Carassius auratus) and Determination of Antibacterial Susceptibility
Authors: Özavci Volkan , Dolgun Hafize , Kirkan S¨ukr¨u
Published: June 2023

Citrobacter freundii is a zoonotic pathogen that causes skin injuries and high mortality rates in fish. This study aims to determine the presence of C. freundii and antibiotic susceptibility in 50 goldfish (Carassius auratus) skin wounds with local bleeding between the ages of 8–18 months in three regions (A, B, and C) located in the West of Turkey. C. freundii (22/50; 44%) strains were isolated from wound swab samples by phenotypic and genotypic methods. C. freundii isolates were positive for H2S, mannitol, and indole, and were negative for the gas formation and urea. All C. freundii isolates showed 96% similarity to C. freundii strain BAO2749 according to the Sanger sequence method. Isolates were also resistant to ampicillin at 57.09% and susceptible to cefoperazone and sulfamethoxazole-trimethoprim by 100%. Statistical analyses were evaluated at a confidence interval of 95%. A p value < 0.05 was considered statistically significant. In conclusion, C. freundii isolates can play a significant role in the pathophysiology of infections in goldfish (Carassius auratus). It can also cause commercial losses in businesses. For this reason, it will be beneficial to control C. freundii pathogenicity in aquarium fish with prophylactic applications to improve product quality and treat diseases in ornamental fish farming.
Implementation of Hidden Infections in the SEIR Model Analysis of the Omicron Variant Spread in Bulgaria
Authors: Kounchev Ognyan , Boyadzhiev Georgi , Simeonov Georgi , Kunchev Metodi , Kuncheva Zhana
Published: June 2023

In this paper we study the impact of the hidden cases of Covid-19 spread in Bulgaria by means of the SEIR model, in the period December 15, 2021 – until March 2022. In particular, the numerical experiments based on the hidden cases till mid-January, provide a forecast of the peak of the infectious curve about February 8, 2022, and reaching the maximum of about 90 000 cases. The forecast shows that end of the epidemics (in Bulgaria) would be in mid-May, 2022. This forecast is compared to the previous forecasts based on the same data excluding hidden cases; they have shown that the peak will be about February 28, reaching about 75 000 cases and will vanish until end of May. As seen in Fig. 3, our forecast of the end of the particular wave of epidemics shows just two weeks difference with what happened in real life – the wave ended in the first week of June. It is curious, that though the peak of the curve in thehidden cases approach has shifted to February 8, the cumulative number of cases in both approaches is nearly the same. More details on the methods used in the present paper and the non-hidden cases study, are provided as well.
Mnemonic Ecologies
Authors: Pieck Sonja K.
Published: June 2023

An exploration of the Green Belt conservation project between the former East and West Germanies and its relationship to emergent ecosystems, trauma, and memorialization.

The first book-length scholarly treatment of Germany's largest conservation project, the Green Belt, Mnemonic Ecologies by Sonja Pieck presents a new interdisciplinary approach: that effective restoration and conservation of wounded land must merge ecology with memory. Since the Cold War's end in 1989, German conservationists have transformed the once-militarized border between East and West Germany into an extensive protected area. Yet as forests, meadows, and wetlands replace fences, minefields, and guard towers, ecological recovery must reckon with the pain of the borderlands' brutal past. The lessons gained by conservationists here, Pieck argues, have profound practical and ethical implications far beyond Germany.

Can conservation help heal both ecological and societal wounds? How might conservation honor difficult socioecological pasts? Deeply researched and evocatively written, this beautiful, interdisciplinary investigation into the legacy of war and nature's resurgence blends environmental history, ethics, geography, and politics with ecology and memory studies. Amid our rampant biodiversity crisis, Mnemonic Ecologies shows why conservation must include humanized landscapes in its purview, thus helping to craft a new conservation ethos that is collaborative, empathetic, and more sensitive to the connections between humans and the places they inhabit.
No Heavenly Bodies
Authors: Evans Christine E. , Lundgren Lars
Published: June 2023

The compelling and little-known history of satellite communications that reveals the Soviet and Eastern European roles in the development of its infrastructure.

Taking its title from Hannah Arendt's description of artificial earth satellites, No Heavenly Bodies explores the history of the first two decades of satellite communications. Christine E. Evans and Lars Lundgren trace how satellite communications infrastructure was imagined, negotiated, and built across the Earth's surface, including across the Iron Curtain. While the United States' and European countries' roles in satellite communications are well documented, Evans and Lundgren delve deep into the role the Soviet Union and other socialist countries played in shaping the infrastructure of satellite communications technology in its first two decades.

Departing from the Cold War binary and the competitive framework that has animated much of space historiography and telecommunications history, No Heavenly Bodies focuses instead on interaction, cooperation, and mutual influence across the Cold War divide.

Evans and Lundgren describe the expansion of satellite communications networks as a process of negotiation and interaction, rather than a simple contest of technological and geopolitical prowess. In so doing, they make visible the significant overlaps, shared imaginaries, points of contact and exchange, and negotiated settlements that determined the shape of satellite communications in its formative decades.
Playful Wearables
Authors: Buruk Oğuz , Dagan Ella , Isbister Katherine , Segura Elena Márquez , Tanenbaum Theresa Jean
Published: June 2023

An expert introduction to the world of “playful wearables” and their design, with a wide range of engaging examples, case studies, and exercises.

This pioneering introduction to the world of wearable technology takes readers beyond the practical realm (think Fitbits, Apple Watches, and smartglasses) to consider another important side of the technology—the playful. Playful Wearables offers an engaging account of what “playful wearables” are, why they matter, how they work, how they're made, and what their future might hold. The book's authors draw on decades of experience in design, development, and research to offer real-world examples, exercises, and implications, showing how this kind of wearable tech can introduce an invaluable element of play into our everyday lives.

As wearable technology emerges in the ecology of costume and fashion, the authors consider its intimate connection to identity and culture. And they look at the ways in which playful wearables, when smoothly integrated into everyday social experiences, support social interaction. The book then moves on to the mechanics of playful wearables—from design strategies and frameworks to specific methods and game design patterns. All of these elements point to possibilities beyond the realm of games and dedicated play, as the value and uses of playful wearables in the larger world of self, society, and culture become ever more apparent.
The Abundant University
Authors: Smith Michael D.
Published: June 2023

Why our current system of higher education is financially and morally unsustainable and how to address the crisis with the creative implementation of digital technologies.

For too long, our system of higher education has been defined by scarcity: scarcity in enrollment, scarcity in instruction, and scarcity in credentials. In addition to failing students professionally, this system has exacerbated social injustice and socioeconomic stratification across the globe. In The Abundant University, Michael D. Smith argues that the only way to create a financially and morally sustainable higher education system is by embracing digital technologies for enrolling, instructing, and credentialing students—the same technologies that we have seen create abundance in access to resources in industry after industry.

The Abundant University explains how we got our current system, why it's such an expensive, inefficient mess, and how a system based on exclusivity cannot foster inclusivity. Smith challenges the resistance to digital technologies that we have already seen among numerous institutions, citing the examples of faculty resistance toward digital learning platforms. While acknowledging the understandable self-preservation instinct of our current system of residential education, Smith makes a case for how technology can engender greater educational opportunity and create changes that will benefit students, employers, and society as a whole.
Demystifying the Academic Research Enterprise
Authors: Droegemeier Kelvin K.
Published: June 2023

What next-generation scholars need to know in order to thrive, and how they can actively participate in shaping the academic research enterprise.

The academic research enterprise is highly complex, involving multiple sectors of society and a vast array of approaches. In Demystifying the Academic Research Enterprise, Kelvin K. Droegemeier shows next-generation scholars across all disciplines how to become more productive earlier in their career, as well as how to help shape the academic research enterprise. The topics covered include public perceptions of scholarly work and its use in policy; understanding the big picture of funding and national priorities as well as identifying funding sources; research methods; collecting data and materials; writing grant proposals; publishing results; ethical conduct; bias and peer review; intellectual property and compliance regulations; partnerships and collaboration; diversity, equity, and inclusion; and the future of research.

Droegemeier's two principal goals are to enhance and accelerate scholars' understanding of the academic research process and to democratize that understanding, particularly at institutions that traditionally are underrepresented or lack robust resources. While intended for undergraduate and graduate students, postdoctoral scholars, and early career faculty, Demystifying the Academic Research Enterprise is also relevant to mid-career and senior faculty, research administrators, funding organizations, congressional staff, policymakers, and the general public. Droegemeier places scholars in a broader national and international context—not as passive recipients of the existing system but as key actors who actively participate in helping to set priorities, determine policies, drive systemic change, and advance knowledge.
Programming Your GPU with OpenMP
Authors: Deakin Tom , Mattson Timothy G.
Published: June 2023

The essential guide for writing portable, parallel programs for GPUs using the OpenMP programming model.

Today's computers are complex, multi-architecture systems: multiple cores in a shared address space, graphics processing units (GPUs), and specialized accelerators. To get the most from these systems, programs must use all these different processors. In Programming Your GPU with OpenMP, Tom Deakin and Timothy Mattson help everyone, from beginners to advanced programmers, learn how to use OpenMP to program a GPU using just a few directives and runtime functions. Then programmers can go further to maximize performance by using CPUs and GPUs in parallel—true heterogeneous programming. And since OpenMP is a portable API, the programs will run on almost any system.

Programming Your GPU with OpenMP shares best practices for writing performance portable programs. Key features include:

• The most up-to-date APIs for programming GPUs with OpenMP with concepts that transfer to other approaches for GPU programming.

• Written in a tutorial style that embraces active learning, so that readers can make immediate use of what they learn via provided source code.

• Builds the OpenMP GPU Common Core to get programmers to serious production-level GPU programming as fast as possible.

Additional features:

• A reference guide at the end of the book covering all relevant parts of OpenMP 5.2.

• An online repository containing source code for the example programs from the book—provided in all languages currently supported by OpenMP: C, C++, and Fortran.

• Tutorial videos and lecture slides.
May We Make the World?
Authors: Zoloth Laurie
Published: June 2023

An in-depth look at genetic alteration in the natural world and the oppositions to it, seen through the case study of a gene drive for malaria.

May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering—to alter the genome of the mosquito that carries malaria. This technology, called a “gene drive,” can alter the sex ratio in Anopheles gambiae mosquitoes, the key vector for falciparum, the deadliest form of malaria. P. Falciparum kills 400,000 people a year, largely the poorest children in the world among them. In her sobering examination of the issue, Laurie Zoloth considers the leading ethical arguments for and against gene drives, explores the regulatory efforts that have emerged long in advance of the science, and considers the philosophical questions raised by the struggle to eliminate malaria.

The development of a gene drive for malaria will have far-reaching implications for it represents the first use of genetic engineering in the natural world and the first creation of a genetic variant intended to spread in the African wild beyond human control. Drawing on two decades of work, Zoloth brilliantly argues that we can understand the complex moral issues at stake only by carefully reflecting on the science, the nature of the local and global discourse about genetic engineering, and the long history of malaria, which—as it transformed from a worldwide disease to a tropical one—reshaped the world as we know it.
The Hidden Powers of Ritual
Authors: Shore Bradd
Published: June 2023

An illuminating overview of the development, benefits, and importance of ritual in everyday life, written by a leading cognitive anthropologist.

The Hidden Powers of Ritual is an engaging introduction to ritual studies that presents ritual as an evolved form of human behavior of almost unimaginable significance to our species. Every day across the globe, people gather to share meals, brew caffeinated beverages, or honor their ancestors. In this book, Bradd Shore, a respected anthropologist, reaches beyond familiar “big-R” rituals to present life's humbler, overshadowed moments, exploring everything from the Balinese pelebon to baseball to family Zoom sessions in the age of Covid to the sobering reenactment rituals surrounding the Moore's Ford lynchings. In each ritual, Shore shows how our capacity to ritualize behavior is a remarkable part of the human story.

Encompassing both the commonly unlabeled “interaction rituals” studied by sociologists and the symbolically elaborated sacred rituals of religious studies, Shore organizes his conception around detailed case studies drawn from international research and personal experience, weaving scholarship with a memoir of a life encompassed by ritual. A probing exploration that matches breadth with accessibility, The Hidden Powers of Ritual is a provocative contribution to ritual theory that will appeal to a wide range of readers curious about why these unique repetitive acts matter in our lives.
TMEM200A is a potential prognostic biomarker and correlated with immune infiltrates in gastric cancer
Authors: Fang Fujin , Zhang Tiantian , Lei Huan , Shen Xiaobing
Published: June 2023

Background

Gastric cancer (GC) is one of the most common malignant tumors in the digestive system. Several transmembrane (TMEM) proteins are defined as tumor suppressors or oncogenes. However, the role and underlying mechanism of TMEM200A in GC remain unclear.

Methods

We analyzed the expression of TMEM200A in GC. Furthermore, the influence of TMEM200A on survival of GC patients was evaluated. The correlations between the clinical information and TMEM200A expression were analyzed using chi-square test and logistic regression. Relevant prognostic factors were identified performing univariate and multivariate analysis. Gene set enrichment analysis (GSEA) was performed based on the TCGA dataset. Finally, we explore the relationship between TMEM200A expression and cancer immune infiltrates using CIBERSORT.

Results

TMEM200A was up-regulated in GC tissues than that in adjacent non-tumor tissues based on TCGA database. Meta-analysis and RT-qPCR validated the difference in TMEM200A expression. Kaplan-Meier curves suggested the increased TMEM200A had a poor prognosis in GC patients. The chi-square test and logistic regression analyses showed that the TMEM200A expression correlates significantly with T stage. Multivariate analysis showed that TMEM200A expression might be an important independent predictor of poor overall survival in GC patients. GSEA identified five immune-related signaling pathways and five tumor-related signaling pathways significantly enriched in the high TMEM200A expression phenotype pathway. Finally, we found CD8+ T cells is apparently decreased in high TMEM200A expression group. Conversely, eosinophils is increased in high expression group compared with low expression group.

Conclusion

TMEM200A is a potential prognostic biomarker and correlated with immune infiltrates in GC.
Enclaves de una ruta: Adaptaciones para una arquitectura pasiva en la nueva ruta hacia el Canal Beagle
Authors: Borquez Pauvif Catalina
Published: June 2023

No presenta resumen.
Reimaginando el proceso de patrimonialización de la Zona Típica Plaza de Armas de Santiago de Chile a través de los imaginarios urbanos: propuesta metodológica
Authors: Correal Cárdenas Carla
Published: June 2023

Tomando como enfoque teórico-metodológico la vinculación entre la concepción del patrimonio como una construcción social y la teoría de los imaginarios urbanos, se analiza el proceso de patrimonialización de la Zona Típica Plaza de Armas, Congreso Nacional y su entorno. El análisis da cuenta de que este proceso fue realizado desde los imaginarios oficiales que privilegiaron el reconocimiento y protección únicamente de las expresiones materiales del patrimonio urbano, invisibilizando el patrimonio construido desde los imaginarios ciudadanos, relacionado con la dimensión socio-cultural inmaterial. El artículo plantea una forma de actualización y complementación del proceso de patrimonialización de esta zona típica, con el objetivo de construir un nuevo relato patrimonial que incorpore la protección de elementos que configuran las múltiples lecturas, valoraciones y significados que contiene este espacio urbano. Para ello, se construye una propuesta metodológica que contribuye al reconocimiento multidimensional del patrimonio en la zona, utilizando los imaginarios urbanos como una herramienta para rastrear las asociaciones y sentidos que establecen los sujetos con los elementos de la ciudad.
Revalorización de un Paisaje Tejido en la Confluencia Mapocho-Maipo. Rutas y Parque del Agua en Isla de Maipo
Authors: Retamal Espinoza Aníbal
Published: June 2023

La confluencia de los ríos Mapocho y Maipo comprende un territorio en los márgenes de Santiago, en donde hechos físicos y operativos de una confluencia de escala territorial configuran un espacio único donde variables ecológicas, culturales y paisajísticas se destacan dentro de la cuenca. Este enclave geográfico mediado por las aguas conforma un complejo sistema fluvial que modela un modo de habitar e interactuar con el territorio, donde variables antrópicas y procesos ecológicos están vinculados al tejido del agua. Sin embargo, la desatención de esta red de ríos, esteros y canales, posiciona a este paisaje en una condición de fragilidad, en donde presiones como la expansión urbana poco planificada y la contaminación de las aguas se contrapone con el valor paisajístico y ecosistémico innato de esta red tejida de corredores fluviales diversos. De este modo, Isla de Maipo se posiciona como un sitio de oportunidad dentro de la confluencia, en donde la diversidad del tejido del agua y las fragilidades de este se multiplican, siendo necesaria la aplicación de un diseño estratégico que replantee el rol de los corredores fluviales y áreas de confluencia como catalizadores de cambio frente a un paisaje degradado y fragmentado mediante las infraestructuras de paisaje.
Espacio Común como proyecto. El caso de las unidades vecinales latinoamericanas
Authors: Bonomo Umberto
Published: June 2023

El espacio común se puede encontrar en el diseño y en las grandes unidades vecinales que se han construido en América Latina bajo diversas políticas económicas y de Estado. Este artículo pretende demostrar que uno de los mayores aportes de la producción urbana y habitacional de la arquitectura moderna en América Latina es precisamente la calidad del espacio común proyectado. De hecho, en países como Chile, Venezuela, Argentina, Brasil y Perú, se construyeron notables unidades vecinales entre los años 40 y 70 del siglo XX, en las que el espacio común jugó, y sigue jugando hoy, un papel fundamental en la definición de las formas de vida de los habitantes. Estos barrios son entornos urbanos específicos, generalmente verdes y peatonalizados, que ofrecen una alta calidad de vida a sus residentes. Las características espaciales y formales de estas experiencias ejemplares de la arquitectura moderna representan una oportunidad para profundizar los aspectos teóricos y las discusiones contemporáneas asociadas con el espacio común. Estos casos son relevantes porque nos permiten determinar con mayor precisión las dinámicas espaciales que relacionan la ciudad con la arquitectura, y al mismo tiempo ofrecen a la disciplina un amplio campo de trabajo y diseño: el espacio común.
Piedra Roja: ni suburbio ni ZODUC
Authors: Leal Velasco Juan Pablo
Published: June 2023

Este artículo aborda modos de vida de reciente creación formados por el desarrollo urbano planificado en la periferia de la ciudad, explorando las relaciones de dependencia con la ciudad y la interacción entre sus habitantes. Lo anterior, mediante un examen del caso de la ZODUC de Piedra Roja en la zona norte de Santiago, que conecta su análisis con las explicaciones existentes en temáticas de los suburbios y los procesos de fragmentación y segregación. Se usa el marco metodológico de la sintaxis espacial para analizar su configuración desde una escala metropolitana y comunal, y desde la integración de segmentos y tramos del sector. Junto con ello, se hace un análisis comparativo de las prácticas espaciales de los residentes. Los resultados respaldan que en la zona norte de la capital, se ha construido una innovadora forma de desarrollo urbano, en la cual se densifica el espacio residencial y se minimizan traslados hacia las afueras del sector. Aun cuando se asume que este proceso de desarrollo urbano permite la construcción de una nueva forma de vida contenida en un espacio que parece ser autosuficiente, es posible detectar defectos de accesibilidad y conectividad explicados en la presencia de barreras simbólicas.