bluuebunny/crossref_metadata_2025 huggingface dataset:
Insecurity as An Influential Factor In The Tourism Development of the Historical Center of Quito
Authors: Belén Calderón Galora Susana , Mateo Vásquez Galeas Rafael , Damián Almeida Peñaherrera Jefferson , Leonidas Vizuete Apunte Jorge , Andrés Terán Andrade Jairo
Published: January 2025

Objective: The objective of this study is to investigate insecurity as an influential factor in the tourist development of the Historic Center of Quito, with the aim of identifying management and control strategies that regularize the social problems of this sector.
 
Theoretical Framework: This topic presents the main concepts and theories that support the research. Security in Quito and its Historic Center and tourism development stand out, providing a solid basis to understand the context of the research.
 
Method: The methodology of the study has a descriptive scope and a mixed approach in terms of data analysis, on the one hand, qualitative through bibliographic research and quantitative through virtual surveys applied to tourists from the Historic Center of Quito.
 
Results and Discussion: The results obtained revealed that informal commerce, homeless people, micro traffic, prostitution, neglected and abandoned real estate, poor lighting, among others, are several of the causes that generate perception of insecurity in tourists.
 
Research Implications: The research involved the identification of the main social problems that generate insecurity in the Historic Center of Quito, and where tourism development can be improved through strategies.
 
Originality/Value: Ecuador, and mainly its capital Quito, is going through unprecedented waves of insecurity, which has generated new social problems such as those detailed in the results obtained (informal commerce, homeless people, micro-trafficking, prostitution, abandoned real estate, among others). others) and that directly influence the tourism sector and its development, which is why this study proposes new measures and strategies according to current needs.
Cigarro eletrônico: conhecimento e uso por estudantes de medicina de uma universidade privada
Authors: Monteiro Porfírio Laila , Paris Bervig Sofhia , Gomes Portocarreiro Bianka , Mello dos Santos Mariana , Martins Moreira de Oliveira Thalita , ALMEIDA DE SOUZA MARIA CRISTINA ALMEIDA
Published: January 2025

Introdução: em 1986, o Brasil implementou o Programa Nacional de Controle do Tabagismo (PNCT) com o propósito de reduzir a prevalência de fumantes e a consequente morbimortalidade relacionada ao consumo de produtos derivados do tabaco. Em 2003, surgiu o cigarro eletrônico (CE), também conhecido como vapers ou vaporizadores, que sem comprovação científica, foram tidos como uma forma de ajudar os dependentes de tabaco a abandonarem o vício. Em 2009, o Brasil proibiu o uso de cigarros eletrônicos. O uso de vapers está relacionado ao surgimento de diversas doenças, entre as quais, se destaca a Evali (e-cigarette and vaping associated lung injury), lesão pulmonar induzida pelo CE. O quadro clínico dessa doença se manifesta com dor torácica e dispneia, mas também são comuns sintomas gastrointestinais como dor abdominal, náuseas, vômitos e diarreia, além de febre, calafrios e perda de peso. Objetivo: verificar entre estudantes de medicina da uma universidade privada seu conhecimento sobre CE assim como utilização deste dispositivo. Material e métodos: estudo quantitativo, transversal, com amostra constituída por acadêmicos do curso de graduação em Medicina da Universidade de Vassouras. A coleta de dados se deu por meio de um questionário eletrônico. Resultados e discussão: participaram da pesquisa 217 estudantes, sendo 66,8% mulheres. A faixa etária predominante foi de 20 (16,1%) e 22 anos (12,9%); 100% dos participantes possuem conhecimento sobre CE, e 43,8% já fizeram uso. Conclusão: evidenciou-se que 100% dos estudantes do curso de medicina conheçam os CE, contudo, muitos desconhecem seus riscos assim como os efeitos de seu consumo, em especial, as manifestações da Evali. Dados obtidos com essa pesquisa sugerem que muitos estudantes têm a falsa crença de que o uso de CE alivia a ansiedade.
Análise Ambiental Integrada de uma Bacia Hidrográfica Costeira Sujeita a Modificações por Urbanização
Authors: Soares Luciana Amorim , Santos Paula Verônica Campos Jorge , Machado Adilson Matheus Borges , Soares Leonardo Silva
Published: January 2025

O processo de urbanização transforma a paisagem e a dinâmica natural do ambiente. Bacias hidrográficas têm sido cada vez mais impactadas por processos urbanos, influenciando na qualidade e disponibilidade dos recursos hídricos, e consequentemente de todos os serviços ambientais dependentes da sistemática de funcionamento da bacia. Como forma de entender as implicações dessas alterações para o ambiente natural e para a cidade, que o presente trabalho objetivou analisar de forma integrada a qualidade e dinâmica da bacia hidrográfica costeira do rio Calhau, localizada na ilha do Maranhão, na capital do estado do Maranhão. Para que tal avaliação fosse possível, foram aplicadas três metodologias, caracterização da área através de indicadores morfométricos relacionados aos aspectos areal, linear e hipsométricos, análise da dinâmica de paisagem para os anos de 2007, 2015 e 2020; e aplicação do Protocolo de Avaliação Rápida da Diversidade de Habitats para pontos entre o alto, médio e baixo curso da bacia. Os resultados demonstram que a bacia possui formato circular, relevo suave estando mais propensa a inundações. Os principais impactos foram causados pelo aumento da malha urbana, diminuição de vegetação, com muitos pontos caracterizados como impactados. Os resultados encontrados podem subsidiar uma gestão mais eficiente para a área.
Descrição e Ensino de Línguas em Roraima
Authors: Procopio Eliabe , Araújo Paulo , Machado Ananda
Published: January 2025

Trata-se de uma coletânea de textos que versam sobre a diversidade linguística e o ensino de língua (PLE/`PLAC) em Roraima. Os autores são de diversas instituições brasileiras: CAP-UFRR, SEED-RR, UPE, UERR, UFRR, UFSCar e UFS. Esta proposta editorial surgiu dentro do PPGL-UFRR, de onde são os organizadores.
واقع التَّنَمُّر على الطلبة ذوي صعوبات التَّعَلُّم من وجهة نظر أولياء أمورهم بمدينة مكة المكرمة
Authors: الحارثي صالحه حسين محمد , أبو العلا نوال أحمد البدوي
Published: January 2025

هدفت الدراسة الحالية الكشف عن واقع التَّنَمُّر على الطلبة ذوي صعوبات التَّعلُّم من وجهة نظر أولياء أمورهم، وإلقاء الضوء على الفروق في مستوى التَّنَمُّر عليهم، تبعًا لمُتغيرات: الجنس، والمؤهل العلمي، والعمر الزمني من وجهة نظر أولياء الأمور بمدينة مكة المكرمة. استخدمت الباحثة المنهج الوصفي التحليلي، واستخدمت الباحثة استبيانًا مكوّنًا من (32) مفردة وطُبّقت الدراسة على عينة مكوّنة من (260) من أولياء أمور ذوي صعوبات التَّعلُّم، وكشفت نتائج الدراسة عن أن مستوى التَّنَمُّر على الطلبة ذوي صعوبات التَّعلُّم من وجهة نظر أولياء أمورهم بمدينة مكة المكرمة جاء بدرجة مرتفعة، بمتوسط (3.868)، وبوزن نسبي (77.36%). وجاء التَّنَمُّر اللفظي في المرتبة الأولى، يليه التَّنَمُّر الاجتماعي، ثم التَّنَمُّر الجسدي، فالتَّنَمُّر الجنسي. كما أسفرت نتائج الدراسة عن أنه يوجد فروق ذات دلالة إحصائية في واقع التَّنَمُّر على الطلبة ذوي صعوبات التَّعَلُّم من وجهة نظر أولياء أمورهم تبعًا لمُتغيّر الجنس؛ لصالح الذكور، وأنه يوجد فروق ذات دلالة إحصائية في واقع التَّنَمُّر على الطلبة ذوي صعوبات التَّعلُّم من وجهة نظر أولياء أمورهم تُعزي لـمُتغيِّر العمر الزمني؛ لصالح أولياء الأمور الذين يتراوح عمرهم من (35 إلى 44) سنة. كذلك أكدت النتائج أنه يوجد فروق ذات دلالة إحصائية في واقع التَّنَمُّر على الطلبة ذوي صعوبات التَّعلُّم من وجهة نظر أولياء أمورهم تُعزى إلى متغيّر المؤهل العلمي؛ لصالح المؤهل الأعلى. وقد أوصت الباحثة بضرورة تعاون كل من أولياء الأمور والمعلمين في إعداد بيئة صفية آمنة، مبنية على أساس بناء القيم لدى الطلبة. كما يتم تقديم ورش عمل لمعلمي ذوي صعوبات التَّعلُّم عن كيفة الحدّ من سلوك التَّنَمُّر بين الطلبة.
Genetically Engineered Peptides for the Biomimetic Mineralisation of Metal-Organic Frameworks
Authors: Lymperopoulou Smaragda , Hoff Samuel , Sola-Rabada Anna , Michaelis Monika , Efimov Igor , Westcott Zayd , Willimott India , Chiacchia Mauro , Heinz Hendrik , Perry Carole , Bradshaw Darren
Published: January 2025

Biomimetic mineralisation of metal -organic frameworks (MOFs) is one of the most promising synthetic strategies for tailor-making MOF and hybrid bio-MOF composites which have significant potential in a variety of applications. While interactions of MOFs with several biological materials including proteins have been well studied, interactions with peptides are still relatively unexplored. Here we use phage display to identify strongly binding peptides for isoreticular MOFs (UiO-66 and UiO-66-NH2). Zeta potential and CD spectroscopy measurements combined with molecular dynamics simulations permit the characterization and explanation of the structure and dynamics of the MOF binding peptides, and differences in conformational behaviour and binding coefficients, allowing the MOF-peptide recognition mechanisms to be determined. The peptides identified through phage display have been successfully used to exert control over MOF crystallinity and particle morphology for UiO-X MOFs, from a synthesis where amorphous products form in their absence. The findings of this work have significant implications for understanding MOF-peptide interactions, which will be critical for the design and control over MOF structures and for bio-centered applications in the future.
Flow of Power Law Fluids in Tubes of Elliptical Cross Sections
Authors: Sochi Taha
Published: January 2025

In this paper we continue our previous investigation about the use of stress function in the flow of generalized Newtonian fluids through conduits of circular and non-circular (or/and multiply connected) cross sections where we inspect the flow of power law fluids in tubes of elliptical cross sections. We derive analytical expressions for the flow velocity profile and for the volumetric flow rate. We also develop numerical algorithms for computing the velocity profile and the volumetric flow rate for this flow where these algorithms produce virtually identical results to the results obtained from the aforementioned analytical expressions. The obtained analytical expressions were tested against the available analytical expressions for the special cases of Newtonian flow in circular tubes, Newtonian flow in elliptical tubes and power law flow in circular tubes and the results were identical. The obtained analytical expressions were also tested for sensible trends, tendencies and correlations and they passed all these tests.
ACTUAL ISSUES OF FORMATION OF ANTI-LUDOMANIA LEGISLATION IN THE REPUBLIC OF KAZAKHSTAN
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Seriev B.A. , Khamzina Zh.A. , Taubayev B.R. , Aitimov B.Zh. , Konysbekova M.R.
Published: January 2025

The purpose of the proposed study is to conduct a legal expert analysis of cases of ludomania in the Republic of Kazakhstan, to conduct a scientific study of the causes of ludomania, to conduct a study of the legislative acts of the Republic of Kazakhstan and some foreign states against ludomania and to draw legal scientific conclusions on the formation of anti-ludomania legislation in the Republic of Kazakhstan.

Recently, in connection with the occurrence of ludomania, a negative phenomenon for society, the number of which is increasing and negatively affects human behavior, there is an increasing need for a scientific study of this problem in science. Developed states have been pursuing state policies in a variety of ways, depending on the specifics of their state-building and legal systems. In the conditions of the Republic of Kazakhstan, the legislative policy against ludomania should have its own special character. Since legislation is the most effective means of influencing public relations, the normalization of legislative regulation from a scientific point of view is an urgent problem.Therefore, the authors propose to first study the formation of anti-ludomania legislation from a legal scientific point of view.

In the research work, the methods of scientific research of law were widely used. In the discussion part of the article, logical methods in particular, if the methods of induction, deduction and analogy are used. Comparative legal methods were used to identify gaps and shortcomings in the legislation. This study is funded by the Science Committee of the Ministry of Science and higher education of the Republic of Kazakhstan (No. BR.Program 24992927).
Guidance for reporting 2024 data on zoonoses, foodborne outbreaks and antimicrobial resistance
Authors:   European Food Safety Authority (EFSA), Amore Giusi , Beloeil Pierre‐Alexandre , Boelaert Frank , Fierro Raquel Garcia , Rizzi Valentina , Rossi Mirko , Stoicescu Anca‐Violeta
Published: January 2025

Abstract
This technical report provides guidance for reporting countries on how to submit their isolate‐based quantitative antimicrobial resistance data, and data on the prevalence of zoonoses and microbiological agents and contaminants in food, food‐borne outbreaks, animal populations and disease status. To collect these data, EFSA has created the Data Collection Framework (DCF) application. This report includes data dictionaries to guide the reporting of information derived from 2024 under Directive 2003/99/EC, Regulation (EU) 2017/625, Commission Implementing Regulation (EU) 2019/627 and Commission Implementing Decision (EU) 2020/1729. The objective is to explain in detail the individual data elements of the EFSA data models that are to be used for XML data submission through the DCF. In particular, it explains the data elements to be reported, including information about the data type, a reference to the list of permitted terms and any additional business rules or requirements that may apply.
Primeiras experiências docentes de língua japonesa em um centro de línguas pela perspectiva de egressos
Authors: Secone Isabella Hoglhammer , Messias Rozana Aparecida Lopes
Published: January 2025

Este artigo aborda o desenvolvimento de professores de japonês como língua estrangeira no âmbito de um Programa de Extensão da UNESP, campus de Assis (SP), conhecido como Centro de Línguas e Desenvolvimento de Professores (CLDP). Buscou-se compreender de que forma os egressos do curso de Letras Português/Japonês, que atuaram no CLDP durante sua graduação, descrevem e refletem acerca de suas primeiras experiências docentes nesse Programa de Extensão. Partiu-se da ideia de que o CLDP se configura como um terceiro espaço nos processos de formação inicial docente. A metodologia adotada foi baseada nos pressupostos do estudo de caso. Os dados analisados mostraram que, para os participantes da pesquisa, esse Programa de Extensão representa um espaço de formação docente indispensável para a atual configuração do curso de Letras no campus de Assis, assim como para o início da construção profissional daqueles que por ele passam.
A mesterséges intelligencia alkalmazásának egyes kérdőjelei : A nagy nyelvi modellek néhány kihívása
Authors: Ollári Viktor Szilárd , Surányi Zsolt Mihály
Published: January 2025

21. század elejére az IT/IKT-megoldások a mindennapi élet teljes vertikumát átszőve kiemelt stratégiai szerepkörbe kerültek. 2022-ben az MI (ChatGPT) terén a kutatók olyan áttörést értek el, amely elérhető közelségbe hozta a technológiai szingularitást (mesterséges szuperintelligencia). A nagy nyelvi modellek (LLM) széles körű alkalmazást biztosító potenciál mellett, súlyos viselkedési függőséget okozhatnak. Ez – a vonatkozó szakirodalom elemzése alapján – globális problémának tekinthető, de különösen a honvédelmi, rendvédelmi, katasztrófavédelmi és nemzetbiztonsági szféra területén jelent kiemelt problémát. Szükségesnek látjuk a vázolt fenyegetés folyamatos elemzését és kutatását az említett kiemelten kritikus területek vonatkozásában.
Boimedical Waste Management Towards Minimising Environment Toxicity Parameters on Safetly Aspects
Authors: Gopal A , Namdeo Devendra Kumar
Published: January 2025

Biomedical waste management is a critical aspect of ensuring environmental sustainability and public health safety. With the increasing generation of biomedical waste due to advancements in healthcare facilities and population growth, the effective and safe disposal of this waste has become a pressing concern. This study aims to evaluate biomedical waste management practices, focusing on minimizing environmental toxicity and enhancing safety parameters. It explores the segregation, collection, transportation, treatment, and disposal methods employed in healthcare facilities, highlighting their impact on environmental and human health. Emphasis is placed on innovative technologies such as autoclaving, microwaving, and chemical disinfection, alongside sustainable practices like recycling and reusing non-hazardous materials. The study also examines regulatory frameworks, compliance levels, and the role of awareness and training among healthcare personnel in achieving optimal waste management outcomes. The findings underscore the need for stricter enforcement of guidelines, investment in modern waste treatment technologies, and the adoption of eco-friendly practices to mitigate toxicity risks. This research contributes to developing an integrated approach to biomedical waste management, ensuring environmental protection and safeguarding public health.
A Gel Study of Selected Medicinal Plants for Treatment of Skin Disease
Authors: Das Amit , Sarkar Ashish
Published: January 2025

The current research focuses on assessing the effectiveness of medical herbs in the preparation of topical gels to manage skin ailments. Further, for the plant selection, the roots of Rubia cordifolia were taken since they were known to be effective in treating ailments. The roots were authenticated, shade dried and then extracted using ethanol. The obtained extracts were further used in gel formulations through various polymers such as Carbopol 934, HPMC K4, and HPMC K15. These gels were subjected to checks on their stability, cohesiveness and their pH level and phytochemical potentials. Some of the increases chemical compounds known to be useful including alkaloids, flavonoids, anthraquinones, glycosides, tannins steroids, phenol, and saponin were further confirmed through other tests. This work highlights that in accomplishing our research objectives, Rubia cordifolia root extracts show great promises in the formulation of topical antidermatophytic agents, thus aspiring to advance the knowledge of herbal medicine therapeutics.
A study of any association between organizational climate on communication, decision-making and conflict handling aspects
Authors: Augustine Priyanka , Bora Rustam
Published: January 2025

This research focuses on the correlation between the organizational climate and four important organizational activities namely communication, decision making and conflict solving. Organizational climate which can be described as the employees’ perceptions of the organization’s environment is assumed to affect the ways in which the employees interact, problem solve and decide. A quantitative survey and qualitative interviews were used to collect data from employees in different industries. The measures employed in the study included those that have been developed and validated to measure dimensions of organizational climate, communication satisfaction, decision making and conflict solving styles. The results suggest that support, autonomy and openness are positively related to communication satisfaction, decision making and conflict management. More specifically, supportive climates were characterised by higher levels of communication openness and a more cooperative approach to conflict than a competitive or avoidant one. The results of the regression analysis showed that the openness of communication and supportiveness were the most significant correlates of positive communication and conflict-solving behaviors. The qualitative data supported these conclusions, indicating that people in open and autonomous work environments reported they were able to participate in decision making and manage conflicts constructively.
Evolución metropolitana contemporánea.
Authors: Sousa-González Eduardo
Published: January 2025

Seguramente se estará de acuerdo en que la manifestación fenomenológica vinculada con las ciudades y de éstas, su evolución en zonas metropolitanas es paulatina, progresiva, replicable y ciertamente irreversible; indudablemente esta expresión del espacio territorial ocurre no solo en México como país, ya que la expresión de lo urbano en la contemporaneidad, se percibe claramente con diversas dinámicas expansivas en el sur global y prácticamente en todo el mundo conocido.
            No cabe la menor duda, que el futuro global tendrá indiscutiblemente una tendencia evolutiva y progresiva en el crecimiento del número y la dimensionalidad de las ciudades; en donde muchas de ellas en su proceso evolutivo transformacional se convertirán en metrópolis y aquellas que ya lo son, seguramente continuarán con su crecimiento expansivo periférico ensanchando su espacio territorial ocupando procesalmente y sin tregua el suelo originario quizá ad perpetuam.
CONSUMER-EXPERT INTERACTION IN PRODUCT CHOICES: REVOLUTIONIZING CONSUMER DYNAMICS WITH AUTONOMOUS EXPERTS IN A MULTIDISCIPLINARY FRAMEWORK
Authors: Dahiwal Rushikesh
Published: January 2025

Consumer dynamics, encompassing preferences, behaviors, and decision-making processes, have grown increasingly intricate within today’s diverse and choice-saturated markets. Autonomous experts—whether human, AI-powered, or hybrid—have emerged as influential facilitators, transforming consumer interactions by offering impartial, empathetic, and technology-enhanced guidance. These experts empower consumers to make informed choices with greater clarity, confidence, and satisfaction.This study presents a multidisciplinary framework that investigates the critical role autonomous experts play in reshaping consumer decision-making. Incorporating insights from psychology, behavioral economics, marketing, communication studies, and technology, the framework demonstrates how these experts build trust, counteract cognitive biases, and facilitate personalized yet unbiased decisions. By analyzing key interaction stages—such as trust development, needs evaluation, and post-purchase support—the study illustrates how autonomous experts influence and adapt to evolving consumer behaviors.To bridge theoretical insights with practical applications, the paper examines their role in sectors like retail, healthcare, and financial services, focusing on their ability to address challenges such as decision fatigue, inclusivity, and ethical data practices. By proposing actionable strategies and tackling ethical considerations, this research highlights the transformative potential of autonomous experts and offers a strategic roadmap for revolutionizing consumer engagement.
INTANGIBLE CULTURAL CONSERVATION AND NATURE PROTECTION THROUGH SPIRITUALISM IN UTTARAKHAND
Authors: Sahani Ashok Kumar
Published: January 2025

The Identity of every civilization is associate with its cultural heritage, In every human societies it is found that protection of nature and its natural resources in different forms. In prehistoric era Man lives in the lap of nature and nature worship is known as naturism which is the ancient form of religion. Worship to Sun, Moon, Earth, Mountains are found in every civilization since past. Nature worship is often considered the primitive source of modern religious believes. Common to most forms of nature worship is a spiritual focus on the individual's connection and influence on some aspects of the natural world and reverence towards religion. The reverence for these deified natural forces was expressed through various rituals, including food offerings, sacrifices, and festivals. Sacred groves were considered the dwelling places of these deities, and entering such spaces was often restricted to priests or those performing rituals. The concept of Prakriti, or nature, in Hindu philosophy further emphasizes the divine nature of the natural world. Rituals often involve offerings to rivers, trees, and mountains, which are seen as embodiments of the divine feminine energy popularly known as Shakti.
EXCHANGE RATE, GDP, AND INTEREST RATE AS DRIVERS OF IT EXPORTS IN INDIA: A REGRESSION-BASED STUDY
Authors: Santosh. N  , M. Muniraju
Published: January 2025

This research explores what drives India’s IT exports, focusing on how exchange rates, economic growth, and interest rates play a role. Using data from 2012 to 2022, daily fluctuations in the Indian rupee-to-dollar exchange rate were averaged annually to capture trends, while yearly IT export figures (in ₹ crore), GDP changes, and interest rates were sourced from official reports. Over the ten-year period, IT exports averaged ₹710,212 crore, though this varied widely by year. The exchange rate between the Indian rupee and US dollar also shifted considerably, averaging 65.74 with noticeable fluctuations. Economic growth, measured by GDP, saw ups and downs—even dipping into negative territory during tough years—while interest rates ranged from historic lows to nearly 8%.The data shows that currency rates have a major impact on IT exports. A stronger rupee against the dollar exhibited a strong correlation with increased export income, accounting for nearly 92% of the observed fluctuations. In contrast, GDP changes and interest rates had little direct influence when considered independently. However, when paired with exchange rates, interest rates became relevant, suggesting combined effects on export performance. While some overlap between variables was noted, the models remained reliable.These findings highlight the outsized influence of currency dynamics on India’s IT sector. For businesses, managing exchange rate risks is critical to maintaining stability. For policymakers, fostering a predictable currency environment could help sustain India’s competitiveness in global IT markets.
CAPACITY BUILDING INITIATIVES FOR SELF-HELP GROUPS (SHGS): AN EVALUATION OF RAJEEVIKA'S INTERVENTIONS
Authors: Verma Khushboo
Published: January 2025

This research article assesses the capability enhancement programmes that Rajeevika, under the Rajasthan Rural Livelihoods Project (RRLP), has implemented to enhance the SHGs. These schemes shall assist to increase women’s banking facilities along with skill building and socio-economic improvement. In this study, both quantitative and qualitative research findings explain the effectiveness of the said interventions on SHG performance, member’s capacity and the general improvement of the community. The results depict the increased levels of understanding in money affairs, employment opportunities, and weak areas in choice making but are faced with resource constraints and cultural barriers.
THE ROLE OF PRINT MEDIA IN SHAPING PUBLIC HEALTH OUTCOMES: A COMPREHENSIVE REVIEW
Authors: Hussain Fahmina , Gautam Santosh Kumar
Published: January 2025

This theoretical study investigates how health-related material in print media affects public health by synthesising current data to grasp its influence in determining public health results. Even with the digital revolution, print media—including newspapers, periodicals, and pamphlets—remains a major source of information. Key topics include the spread of health information, the way health concerns are framed, and the impact on public perspective and behaviour are underlined in the review. Research show that print media may influence health policy debate, increase knowledge of health concerns, and encourage good practices. Still, these results are much influenced by the accuracy, bias, and depth of the material. Print media's health-related material reflects more general social, economic, and political settings, therefore impacting its presentation and reception. Moreover, the different degrees of media literacy among the people help to control the influence of such material. The evaluation also covers ethical obligations of print media in health communication as well as the possibility of false information. This study offers a complete framework for comprehending the intricate interaction between print media and public health by combining theoretical viewpoints from psychology, public health, and communication studies. The results underline the importance of planned, evidence-based health communication in print media to improve its favourable influence on public health outcomes.
Afectación Económica y Psicológica por la pandemia: mercados San Roque, Santa Clara y la Floresta de la ciudad de Quito
Authors: Medina Carranco Nancy , Toala Sánchez Glenda Marilú , Torres Olmedo Jeaneth Margarita , Montesdeoca Espín Lourdes Cumandá
Published: January 2025

En este artículo se evidencian los niveles de ansiedad y depresión en los y las trabajadores(as) de los mercados de San Roque, Santa Clara y La Floresta de la ciudad de Quito que, en parte, se deben a la afectación económica significativa que se produjo en su economía. Para efectuar este análisis se recopilaron datos aplicando una encuesta a 542 trabajadores(as) de los mercados mencionados. Se evaluó la ansiedad y la depresión aplicando test especializados, válidos y confiables. Se encontró que pocos comerciantes presentaron un grado severo de ansiedad y depresión; pero también se evidencia una grave afectación a su economía.
Inteligencia Artificial: Machine Learning, para Detección Temprana de Plagas y Enfermedades de Cultivos Básicos, Nicaragua
Authors: Urbina Cienfuegos Saira María , Bravo Rivas Jazcar Josué
Published: January 2025

El presente artículo, muestra aspectos relevantes del proceso de desarrollo de la aplicación móvil que incorpora técnicas de Machine Learning para detectar de forma temprana plagas y enfermedades en cultivos de granos básicos como maíz, frijol y sorgo, estos son indispensables para el consumo humano en Nicaragua. Se utilizó metodología de desarrollo ágil Scrum, se adoptaron tecnologías como Android Studio, lenguaje de programación Java, Google Teachable Machine para entrenamiento del modelo de aprendizaje automático y TensorFlow Lite para incorporar modelo en la aplicación móvil. Los resultados muestran un Sprint con sus historias de usuarios, estas se convirtieron en funcionalidades que incluyen el modelo para el reconocimiento de imágenes con precisión de 95.8% utilizando un conjunto de datos de 252 imágenes de cultivos sanos y enfermos. La metodología indica organización de la programación según patrón Modelo – Vista – Controlador y métricas utilizadas por el modelo. Las conclusiones hacen énfasis en detalles de los resultados obtenidos en Sprint#1. Al final, también se mencionan retos a superar al aplicar aprendizaje automático en el sector agrícola.
Restablecimiento de la salud oral de un paciente con tabaquismo y adicción a sustancias psicotrópicas: reporte de caso
Authors: Lugo Vásquez Paula Valentina , Reyes Cevallos Cecilia Amparo
Published: January 2025

El tabaquismo y el consumo de sustancias ilícitas tienen un impacto negativo sobre diferentes áreas de la vida de la persona que está involucrada con estos hábitos. Se han descrito varias consecuencias sobre la salud oral que van desde mal aliento y caries hasta pérdida de dientes y cáncer oral. Materiales y métodos: Paciente masculino de 51 años acude a consulta presentando molestias en su cavidad oral. Refiere consumir tabaco y sustancias psicotrópicas (cocaína y sus derivados). Resultados: se realizó el diagnóstico y, aplicando distintas especialidades odontológicas, se culminó el tratamiento integral del paciente. Conclusiones: se logró restablecer la salud oral del paciente con tabaquismo adicción a sustancias psicoactivas, de manera que recupere las funciones estomatológicas y estética, mejorando su calidad de vida.
¿Pueden los algoritmos tener una relación sinérgica con el neoliberalismo? Ensayo sobre las sociedades de control y la gubernamentalidad.
Authors: Vich Juan José
Published: January 2025

El presente trabajo busca analizar de qué manera entran en relación la gubernamentalidad neoliberal con la gubernamentalidad algorítmica. A partir de la caracterización teórica de los diferentes fenómenos que las componen, nuestra hipótesis plantea que entre ambas gubernamentalidades hay una relación de tipo sinérgica.
La noción de gubernamentalidad habla acerca de la forma en que somos gobernados y nos gobernamos a nosotros mismos. El neoliberalismo busca establecerse como racionalidad, mientras que instaura a la competencia como norma y a la empresa como modo de subjetivación. Para esto se nutre de técnicas gubernamentales que conllevan a la optimización del individuo. Estas técnicas son amplificadas por algoritmos maquínicos que son capaces de recolectar y procesar datos que después son usados para la perfilización.
A new test system for Salmonella detection in food products by competitive immonoassay
Authors: Kiseleva E. P. , Mikhailopulo K. I. , Sviridov O. V.
Published: January 2025

Detecting Salmonella in foods is topical due to the known cases of salmonellosis epidemics. Immunochemical methods including enzyme-linked immunosorbent assay (ELISA) have been widely used in Salmonella detection. Traditionally, ELISA of Salmonella is based on detecting lipopolysaccharide (LPS), which is considered to be the main structural component of the outer membrane of the cell of Gram-negative bacteria. Core (conservative LPS element common to all Salmonella) and O-antigen (hypervariable LPS element) are available for interaction with antibodies. It was shown using commercial MAb 5D12A (to the core of LPS) or MAb 10D9H (to the common epitope of the O-antigen of Salmonella serogroups A, B and D) that in the Salmonella culture obtained during sample preparation, traditional for the analysis of these bacteria in foods, LPS is present mainly outside cells, in the medium (no less than 90 %). It has been found that the addition of centrifugation to the standard sample preparation procedure to separate bacteria from the medium and a subsequent analysis of the medium can expand the test-system working range towards lower LPS concentrations and increase the analytical sensitivity. It has been shown that immobilization of the bovine serum albumin (BSA)-LPS conjugate in the wells of a microplate immunosorbent allows one to obtain a more homogeneous coating than immobilization of LPS itself. We have elaborated 2 test systems for Salmonella detection in foods by competitive ELISA of LPS secreted in medium. In each of the two test systems, the BSA-LPS conjugate is immobilized on the solid phase, and in the liquid phase there are either MAb 5D12A or MAb 10D9H. The sensitivity of the analysis for each test system is 105 CFU/ml. The test system based on MAb 5D12A is advan tageous since it allows detecting all Salmonella regardless of serotype.
Genotypic features of the relationship between the components of the antioxidant complex of high blueberry fruits and the content of organic compounds during introduction in Belarus
Authors: Rupasova Zh. A. , Avramenko S. N. , Ushakova A. V. , Pavlovsky N. B. , Drozd O. V. , Bely P. N. , Shpitalnaya T. V. , Vecher N. N.
Published: January 2025

The article presents the results of a comparative study in the southern agroclimatic zone of Belarus in the taxonomic series of 6 new introduced varieties of highbush blueberry: early ripening – Chanticleer, Hannah’s Choice, midseason – Bluegold, Harrison, and late ripening – Aurora, Rubel, as well as the corresponding to these maturity groups zoned varieties Weymouth, Bluecrop and Elliott structures of correlation links between the levels of antioxidant and enzymatic activity, on the one hand, and 12 indicators of biochemical composition, on the other.

Significant genotypic differences in the orientation and strength of these links were revealed due to the individual characteristics of the biochemical composition of the tested objects, indicating a pronounced variety specificity of the analyzed traits.

A noticeable similarity was revealed in the representatives of different varietal groups in the spectra of organic compounds most significant for formation of the antioxidant complex of fruits, which was most clearly manifested in early and late ripening varieties and consisted of the dominant role of catechins, tannins, leucoanthocyanins and flavonols, and in midripening varieties – along with tannins and leucoanthocyanins, also free organic and hydroxycinnamic acids.

At the same time, soluble sugars and ascorbic acid had the least effect on the antiradical properties of blueberry fruits. A uniform sequence of blueberry taxa was established in the order of decreasing the interaction level of individual components of the antioxidant complex of fruits with the content of organic compounds of different chemical nature with the greatest manifestation of the strongest direct correlation links with sources of antioxidant, peroxidase and polyphenoloxidase activity in the Hannah’s Choice variety, and in the Aurora variety – with sources of catalase and, to a lesser extent, the peroxidase activity against the background of a minimum number of such interactions in the Harrison variety, which was 1.6–2.1 times inferior in this feature to the leading blueberry taxa.
On the granting nature protection status to the Polesie State Radiation and Ecological Reserve
Authors: Tchaikovsky A. I. , Kudin M. V. , Grummo D. G. , Maksimenkov M. V. , Ustin V. V.
Published: January 2025

The Polesie State Radiation and Ecological Reserve (PSRER) has been operating since 1988 within the Belarusian sector of the evacuation (exclusion) zone after the Chernobyl accident. The specific composition of radionuclide fallout, the presence of fuel particles in ecosystems and the high density of radioactive contamination of the soil determined the “reserve” status of PSRER and long-term strategic aspects of its development. The key objectives of creating PSRER are to implement a set of measures to prevent the removal of radionuclides beyond its territory, the study of the state of natural plant complexes, wildlife, radiation and environmental monitoring, and radio-biological and radio-ecological research. At the same time, despite its high conservation potential, PSRER is not a specially natural protected area (SNPA). The article presents the results of analysis of the compliance of the PSRER territory with the general and special criteria for selecting natural territories for SNPA granting, established by Article 16 of the Law of the Republic of Belarus “On Specially Natural Protected Areas”. There are compelling reasons for giving this natural territory the status of SNPA with the category of a reserve: the territory meets 5 general criteria (criteria 2.1, 2.2, 2.3, 2.4, 2.7) and all 3 special criteria presented for declaring natural territories a reserve.
Directions for stimulating the expansion of the practice of using domestically selected vegetable seeds
Authors: Makrak S.
Published: January 2025

A developed mechanism for implementing instruments of state support for the seed industry in the context of stimulating the use of domestic vegetable seeds is presented, including an algorithm for assessing the priority of specific measures to motivate their purchase.

Based on an analysis of the production and economic indicators of vegetable cultivation in a focus group of commodity producers, practice-oriented measures were developed to increase the efficiency of the vegetable growing industry, aimed at the use of compensation payments for certain types of material resources.
Secondary osteoporosis: a disease with serious consequences
Authors: Sergeeva-Kondrachenko M. , Terina N.
Published: January 2025

Secondary osteoporosis (OP) develops as a result of somatic pathologies (endocrine, genetic diseases, kidney damage, gastrointestinal tract, etc.), lifestyle habits or medications. Any patient with suspected secondary OP must undergo a series of laboratory tests (full clinical blood test, biochemical blood test, blood test for 25-hydroxyvitamin D, parathyroid hormone, etc.). The “gold standard” for instrumental diagnosis of OP is dual-energy X-ray densitometry of the lumbar spine and proximal femur to assess bone mineral density. Treatment of secondary OP is etiological, aimed at identifying and eliminating the underlying cause of the disease, which usually involves discontinuation of medications (if possible) and correction of modifiable risk factors. If it is impossible to influence the cause of secondary OP, pathogenetic therapy is used, including antiresorptive drugs, agents that enhance bone formation, and monoclonal antibodies. It is important to remember that the effectiveness of treatment of OP is influenced by indicators of phosphorus-calcium metabolism, therefore, before starting pathogenetic therapy, it is necessary to determine the levels of calcium, phosphorus and 25-hydroxyvitamin D in the blood, bring these indicators to normal values, and then continue taking these drugs along with pathogenetic therapy. To do this, they recommend a diet balanced in calcium, phosphorus and proteins, and the prescription of vitamin D supplements and calcium salts. One of the effective means for normalizing phosphorus-calcium metabolism is the drug Osteomed Forte.
Factors of early neonatal maladaptation of late preterm infants
Authors: Panina N. , Ippolitova L. , Kaledina E. , Kogutnitskaya M. , Korotaeva N.
Published: January 2025

Late preterm infants are more susceptible to various unfavorable factors than preterm infants. The leading place in the structure of morbidity, as well as the formation of long-term unfavorable outcomes in this group of children is occupied by respiratory disorders, impaired or delayed neurodevelopment. In order to study in detail the pathological conditions leading to adaptation disorders, we retrospectively analyzed the data of developmental histories of late premature infants and delivery histories. The relationship between placental abnormalities, including fetal growth and developmental delays, fetal conception, history of pregnancy termination, low birth weight, age of the woman in labor and increased need for respiratory support, as well as clinical manifestations of cerebral ischemia in newborns at 34 0/7–36 6/7 weeks gestation was revealed
Electronic medical record in neonatology. Development and implementation experience
Authors: Svetlakova D. , Starkov V. , Ankudinov N. , Shestak E. , Dodrov D.
Published: January 2025

Electronic medical record (EMR) improves the quality of medical services and the speed of transfer of medical information between organizations and the patient. Purpose. To share the experience of developing a neonatal module and its implementation in a medical organization, and also, to show the advantages and disadvantages of EMR, the problems faced by the authors of the article during the development and implementation of EMR and their solutions. Methods. The experience of developing and implementing the neonatal module of the automated information system Regional Obstetric Monitoring (AIST ROM) on the basis of the Yekaterinburg Clinical Perinatal Center is presented. Results. After studying the regulatory framework, an EMR of the patient was developed and implemented. The neonatal module of AIST ROM includes all the necessary documents. The problems we have encountered in the development and implementation process are common. After studying the literature and taking into account the peculiarities of our medical organization, certain ways of solving them are proposed. Conclusion. EMR in neonatology will improve the quality of care, reduce the number of errors, ensure the availability of information, and reduce the burden on medical personnel.
Support for young scientists in Kazakhstan: current status, problems and solutions
Authors: Rakhmanberdi N. , Zhussupova G. , Skvirskaya G. , Volnuhin A.
Published: January 2025

This article examines the current state of support for young scientists in Kazakhstan, identifies the key problems they face, and suggests solutions to improve the effectiveness of existing measures. The normative acts and programs aimed at supporting young people in the scientific field are analyzed. Specific consideration is given to the present difficulties and potential solutions to enhance the appeal of scientific research careers for young scientists in Kazakhstan. As a result of the research, recommendations are proposed to improve the material and technical base, stimulate scientific activity and create conditions for the full participation of young scientists in scientific processes
Technology of surgical guide development: practical application in implantology
Authors: Osmanova N.
Published: January 2025

Purpose. To examine and describe the steps involved in creating a surgical guide for dental implant installation, and to assess the advantages of using surgical guides compared to traditional implant placement methods. Materials and methods. The study utilized data from cone-beam computed tomography, intraoral scanning, and specialized software for data merging and surgical guide modeling. A clinical case with the installation of three implants was analyzed to evaluate the effectiveness of the method. Additionally, 15 similar cases were reviewed where implant placement was performed without using a surgical guide to compare operation times. Results. The results showed that using a surgical guide reduced the operation time to 23 minutes compared to the average duration of 58 minutes with the traditional method. Conclusions. The use of guides minimizes the need for constant checks and adjustments, reduces the risk of complications, and improves patient comfort by shortening the time spent on the operating table. Patients feel more confident in the outcome since the template minimizes the likelihood of medical errors
Changes in cortisol, prolactin and oxytocin levels in pregnant women after perinatal training programs
Authors: Keshchyan L. , Grishkova N.
Published: January 2025

Purpose. To study changes in the levels of cortisol, prolactin and oxytocin in the blood serum of pregnant women depending on the perinatal preparation program used. Material and methods. The study involved 537 women at 34 weeks of pregnancy, who were divided into 2 groups: main (n=273) – pregnant women who underwent perinatal training under the “Conscious Motherhood” program; comparison group (n=264) – pregnant women who were trained under the program of a traditional maternity school. The levels of the studied hormones were determined by enzyme immunoassay. Results. The initial levels of cortisol, prolactin and oxytocin in the groups did not differ significantly and corresponded to the reference values for pregnant women. After classes in perinatal training programs, the levels of cortisol and prolactin did not change significantly and did not differ between groups. Classes in the “Conscious Motherhood” program increased the content of oxytocin by 2.2 times, while in the comparison group (traditional motherhood school) no significant changes were detected. Conclusion. Thus, perinatal preparation does not affect the levels of cortisol and prolactin. At the same time, classes in the “Conscious Motherhood” program, conducted together with husbands, cause an increase in oxytocin levels, which may have a beneficial effect on the course of childbirth.
PRINCIPLES OF PRESCRIBING CALCIUM SUPPLEMENTS AND VITAMIN D: THE VIEW OF A CLINICAL PHARMACOLOGIST AND RHEUMATOLOGIST
Authors: Potupchik T. , Kapustina E. , Kucherenko A. , Klyuchnikova E.
Published: January 2025

The article analyzes scientific research on the use of calcium and vitamin D preparations. The role of calcium and vitamin D in bone tissue homeostasis is shown. A review of calcium and vitamin D medicines registered in the Russian Federation has been conducted. Special attention is paid to one of the urgent pharmacological and therapeutic problems – safety. Research data demonstrate that calcium and vitamin D supplements have a positive effect on bone metabolism and bone strength. It has been revealed that an overdose of calcium and vitamin D may have undesirable consequences for human health, in particular, increased stone formation and the development of urolithiasis. One of the solutions to the problems associated with the risk of overdose may be the use of biologically active additives Osteomed, Osteo-Vit D3, Osteomed Forte.