bluuebunny/crossref_metadata_2025 huggingface dataset:
Participación como principio ético en investigación para el cuidado con pueblos originarios
Authors: Carrasco Díaz Beatríz
Published: May 2023

Introducción: Desarrollar estrategias de participación como un principio ético puede contribuir a investigaciones culturalmente adecuadas y basadas en prácticas horizontales. Objetivo: Describir las estrategias de participación como aspecto ético en experiencias de investigación para el cuidado con pueblos originarios. Metodología: Revisión narrativa. Se utilizan bases de datos SCIELO, PUBMED, Web of Science, CINAHL y SCOPUS. Las estrategias de búsqueda empleadas fueron: indigenous peoples (OR) Native Peoples (AND) Ethic research (AND) Community (OR) communities. Se realiza cribado por título y resumen de acuerdo con criterios de inclusión establecidos. Se utilizan principios de análisis de contenido para la síntesis de la evidencia. Resultados: se obtienen 17 manuscritos, donde el 100% corresponde a artículos de tipo cualitativo. Se describen tres categorías principales: Estructuras para la participación, métodos para la participación y relaciones de confianza para la participación. Conclusión: El establecimiento de confianzas para participación significa un cambio profundo de las relaciones entre investigadores y los pueblos originarios, que requiere prácticas de investigación orientadas a una participación significativa de la comunidad, enmarcada en guías éticas que tracen la gobernanza de la investigación, con énfasis en la transparencia, acuerdos y mecanismos de reciprocidad claros.
Comparison of radiological changes in symphysis pubis and disease activity parameters in male patients with ankylosing spondylitis
Authors: BİLEN Arif , REŞORLU Mustafa , RESORLU Hatice
Published: May 2023

Introduction: To determine the prevalence of involvement of symphysis pubis among male patients with ankylosing spondylitis (AS) and to analyze the relationship among this involvement, demographic data, clinical activity of the disease and radiological findings.
Methods: Overall, 73 male patients diagnosed with AS who visited our clinic for follow-up were included in the study. In this retrospective study, clinical and radiological parameters were collected. In clinical evaluation, vertebral Visual Analog Scale (VAS) score, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Metrology Index (BASMI) and Bath Ankylosing Spondylitis Functional Index (BASFI) were used. In AP pelvis radiography, symphysis pubis changes were rated as 0–4. Modified Stoke Ankylosing Spondylitis Spinal Score (M-SASSS) was calculated from the cervical and lumbar lateral radiography images.
Results: Symphysis pubis involvement was radiologically observed in 45 patients (61.7%). The mean age (43.9 ± 12.6) of patients with symphysis pubis involvement was higher than the average (36.9 ± 9.0) of patients without involvement (p = 0.026). Average M-SASSS of patients with symphysis pubis involvement (15.9 ± 11.9) was higher than the average of patients without involvement (8.4 ± 7.4), and there was a significant positive correlation between symphysis pubis involvement and M-SASSS (p=0.002). BASDAI and BASMI averages of patients were not significant (p = 0.973 and p = 0.105, respectively).
Conclusion: Symphysis pubis involvement is a common manifestation of AS and can be used to predict vertebral radiological involvement.
Keywords: Ankylosing Spondylitis, Symphysis Pubis, Modified Stoke Ankylosing Spondylitis Spinal Score
The Concept of the Regional Strategy for the Development of Employment in the Amur Region
Authors: Shevchenko K. V.
Published: May 2023

The development of employment in the region, aimed at improving the quality and standard of human life, is carried out through strategizing. Based on the theory of strategy and the methodology of strategizing V.L. Kvint and taking into account the methodology of strategizing the development of labor resources I.V. Novikova, when developing employment, it is necessary to identify, research and develop the main elements of the strategy, which represent the core block — the Concept of the strategy. In this paper, the mission, vision, strategic priorities and their goals are proposed, corresponding to the strategic opportunities identified by the OTSW analysis with the help of strategic analysis of strategic trends, strategic and statistical analysis of employment of the population of the Amur region, taking into account the coherence of interests and backed by competitive advantages. Being the object of regional strategizing, employment, as a socio-economic category, influences such strategic priorities as ensuring a healthy lifestyle and promoting well-being at any age, quality education throughout life, reducing inequality in the social development of the region, ensuring decent employment and promoting economic growth, etc. The presented Concept of the employment development strategy of the Amur Region makes it possible to effectively use existing opportunities by implementing significant strategic initiatives for the development of the region.
The Deepfake Technology: Threats or Opportunities for Customs
Authors: Getman A. A. , Ling Yilan
Published: May 2023

The development of science and technology contributes to the expansion of opportunities for using new ways in various fields of activity — such as remote work, cloud computing, and so on, which makes any activity more convenient and efficient. However, high technologies are not always associated with a positive effect, as new technologies lead to new risks. The article discusses Deepfake technology, a popular artificial intelligence technology, with which it is possible not only to change, but also to fake data, such as images, video, audio. On the one hand, this brings benefits and profits to the film industry, and on the other hand, it can threaten the protection of intellectual property rights. Customs authorities using various technologies need to be prepared to respond to deepfakes. The article is devoted to the issues of taking into account the risks for the customs authorities of countries in connection with the emergence and spread of deepfakes.
Conhecimento da equipe de enfermagem da unidade de transplante no reconhecimento da insuficiência respiratória
Authors: Otoni Raissa Cristina Gonçalves , Cruz Shyrlene Alcione Ribeiro
Published: May 2023

The study aimed to evaluate the knowledge of the hematopoietic stem cell transplant nursing team about the management of Respiratory Failure , as well as to carry out training for this purpose. This is a field research of descriptive-exploratory, quantitative nature. Data collection was carried out between July and August 2021 and had the participation of 20 employees. Two theoretical evaluations (beginning and end) and an in loco simulation were used. The results show that after being trained nurses in the hematopoietic stem cell transplantation sector, improved their general performance when responding to urgent and emergency questions and in their specific knowledge of the main signs and symptoms of respiratory failure and ventilation interventions. The study contributed to reinforce the need for evidence-based nursing practice and the need for permanent education of the team to improve care practices.
Pengaruh Kegiatan Literasi dalam Pembelajaran dan Kreativitas terhadap Kemampuan Menulis Cerpen Siswa SMA
Authors: Damanik Sheren Apregina , Budiyono Herman , Harjono Hary Soedarto
Published: May 2023

Abstrak

Penelitian ini bertujuan untuk melihat sejauh mana pengaruh kegiatan literasi dalam proses pembelajaran dan kreativitas peserta didik dalam menulis cerpen. Desain dan pendekatan yang digunakan dalam penelitian ini adalah pendekatan kuantitatif. Pada penelitian ini, peneliti menggunakan dua kelas subyek penelitian dengan tujuan membandingkan, yaitu kelompok eksperimen dan kelompok kontrol. Teknik pengumpulan dengan tes unjuk kerja dan melakukan kegiatan literasi. Hasil penelitian menunjukkan bahwa kegiatan literasi memberikan pengaruh positif pada siswa dalam pembelajaran siswa dalam menulis cerpen. Hal ini dapat diidentifikasikan dari hasil pengujian statistik t-test. Dengan demikian, dapat dilihat bahwa kegiatan literasi dapat meningkatkan kemampuan siswa dalam menulis cerpen.

Kata Kunci: Literasi, pembelajaran, kreativitas, menulis, cerpen

Abstract

This study aims to see the extent of the influence of kterasi activities in the learning process and the creativity of students in writing short stories. The design and approach used in this study is the quantitative approach. In this study, researchers used two classes of research subjects with the aim of comparing, namely the experimental group and the control group. Collection techniques with performance tests and literacy activities. The results showed that literacy activities had a positive influence on student learning identified from the results of static test t -test. Thus, it can be seen that literacy activities can improve students' ability to write students in writing short stories. This can be a short story.

Keywords: Literacy, learning, creativity, writing, short stories
Pengaruh Media Digital Storytelling terhadap Hasil Belajar Mahasiswa S-1 PBSI Universitas Jambi
Authors: Wulandari Aliska , Harjono Hary Soedarto , Budiyono Herman
Published: May 2023

Abstrak

Perkembangan IPTEK membawa manusia pada kemajuan teknologi dan memudahkan penggunanya termasuk menggunakan media dan sumber belajar berbasis digital dalam proses pembelajaran. Penelitian ini bertujuan untuk mengetahui pengaruh, perbedaan hasil belajar, serta interaksi dari penerapan media Digital Storytelling (DST) terhadap hasil belajar mahasiswa S-1 PBSI Universitas Jambi. Metode penelitian yang digunakan dalam penelitian ini adalah metode eksperimen. Penelitian ini melibatkan dua kelas, yakni kelas ekperimen dan kelas kontrol. Instrumen penelitian ini menggunakan tes dan angket motivasi. Teknik analisis data menggunakan SPSS 19 dan Anova dua jalur. Hasil penelitian ini menunjukan adanya pengaruh yang signifikan dari penerapan media DST terhadap hasil belajar mahasiwa S-1 PBSI Universitas Jambi, dan ada perbedaan hasil belajar pada kelompok mahasiswa motivasi tinggi dan rendah yang menggunakan media DST jika dibandingkan dengan kelompok mahasiswa yang memiliki motivasi tinggi dan rendah namun dalam pembelajaran tidak menerapkan media DST.

 

Kata kunci: media, digital storytelling, belajar

Abstract

The development of science and technology makes us the development of technology and facilitates its users including using media and digital-based learning sources in the learning process. This study aims to know the effect, difference, and interaction of student learning, and  of the implementation of digital storytelling media (DST) to the learning outcome of the Digital Storytelling medium (DST) to the student's learning output of the PBSI University Jambi. The method of used is the method of experiment. This study involves two class, the class of experiment and the class of control. The research of instrument uses test and carrier of motivation. Techniques of data analysis was using the SPSS 19 and ANOVA two-path. This study shows a significant effect of the application of DST media to the results of the study of the S-1 PBSI University of Jambi, and there is a difference in learning outcomes in the high-level student of high school and low-quality which uses DST, when compared with students who have high motivation and low motivation but in learning does not apply DST Media.

 

Key words: media, digital storytelling, study
Persepsi Siswa Kelas VIII Terhadap Pendekatan Saintifik dalam Materi Teks Eksplanasi di SMPN 7 Muaro Jambi Tahun Pelajaran 2018/2019
Authors: Ezalika Ririn , Harjono Hary Soedarto , Priyanto Priyanto
Published: May 2023

Abstrak

___________________________________________________________________

Penelitian ini bertujuan untuk melihat persepsi siswa terhadap penerapan pendekatan saintifik kelas VIII D SMPN 7 Muaro Jambi Tahun Pelajaran 2018/2019 dalam materi teks eksplanasi. Penelitian ini dilatarbelakangi oleh sebuah fenomena bahwa menggunakan pendekatan yang tepat dalam mengajar dapat menumbuhkan minat belajar siswa, metode yang digunakan adalah metode kuantitatif. Penelitian ini dilakukan pada semester ganjil pada tanggal 25 pebruari sampai 28 pebruari 2019. Data penelitian diperoleh dengan cara menyebarkan angket kepada siswa (sebagai data utama) dan wawancara dengan guru bidang studi Bahasa Indonesia. Hasil penelitian menunjjukkan bahwa persepsi siswa terhadap pendekatan saintifik sangat bagus dan memiliki pengaruh yang kuat dalam pembelajaran, hal itu dibuktikan dengan hasil perhitungan uji validitas dengan skor 0,784 dan hasil uji reabilitas dengan skor 0,784. Kemudian hasil perhitungan data dilihat dari segi deskriptif kuantitatif yang menunjjukkan terdapat pengaruh penerapan pendekatan saintifik terhadap persepsi siswa dengan skor 47,67 dan 42,43 < 0,05 (6, 314).

Kata kunci: persepsi siswa, pendekatan saintifik, materi teks eksplanasi

 Abstract

___________________________________________________________________

This research aim to to see perception of student to applying of scientific approach [of] class of VIII D SMPN 7 Muaro Jambi School Year 2018 / 2019 in text items of eksplanasi. This research [of] background by a phenomenon that using correct approach in teaching can grow enthusiasm learn student, method the used [is] quantitative method. This research [is] [done/conducted] [by] [at] anomalous semester on 25 pebruari until 28 pebruari 2019. Research data obtained by propagating enquette to student ( as especial data) and interview with Indonesian study area teacher. Result of research of that perception of student to scientific approach very good and have strong influence in study, that thing [is] proved with result of calculation of validity test with score 0,784 and result of test of reabilitas with score 0,784. Later;Then result of calculation of data seen from quantitative descriptive facet which [is] menunjjukkan there are influence of applying of scientific approach to perception of student with score 47,67 and 42,43 < 0,05 ( 6, 314).

Key Words: perception of student, scientific approach, text items of eksplanasi.
MECHANICAL STUDY OF 9Cr-316SS-1Mo MATERIALS FOR NUCLEAR FUEL CLADDING MATERIALS POWER REACTORS
Authors: Purnama Mayda , Sudjadi Usman
Published: May 2023

Cladding or cladding used for nuclear fuel elements requires special requirements such as good mechanical properties, radiation resistance, corrosion resistance, adequate physical and chemical properties, and low thermal neutron absorption. Materials that are widely used as structural materials for nuclear reactors are beryllium, magnesium, aluminum, zirconium and their alloys. Alloy 9Cr-316-1Mo as Nuclear fuel cladding material. 9Cr-316-1Mo material has been made. The material 9Cr-316-1Mo was chosen as an alternative cladding material because it has good mechanical and chemical properties with a microscopic cross-section of 2.6 barn. At first, the 9Cr-316-1Mo sample was cast withThe composition is 90% 316L Stainless Steel, 9% Chromium (Cr) and 1% Molybdenum (Mo) is added using an electric arc. After casting the alloy,the composition of 9Cr-316-1Mo was tested without heating and then given heat treatment (tempering) starting from 100 0C, 200 0C, 300 0C, 400 0C and 500 0C and allowed to stand for 60 minutes, then tested for hardness (rockwell) , Impact testing, micro structure testing and Chemical composition testing (XRF). The results of the Rockwell hardness test obtained the highest hardness value in the sample without tempering, namely 20.66 HRc and the lowest hardness value in the sample with tempering 500 0C, namely 16.33 HRc. Then the impact test results obtained the highest impact energy value in the sample with tempering 100 0C, which is 0.9996 Joule/mm2 and the lowest impact energy value in the sample with tempering 500 0C, which is 0.9962 Joule/mm2. The results of the microstructure test showed that the structure of 9Cr-316-1Mo still contained ferrite, pearlite and martensite. The testing process is still not fully completed and will be reported later.
ANALYSIS OF OIL ABSORPTION AND FRICTION COEFFICIENT OF BAMBOO POWDER, COCONUT POWDER, GLASS POWDER, AND COPPER POWDER COMPOSITES FOR CLUTCH PADS
Authors: Risyuma Iqbal , Fitri Muhamad
Published: May 2023

This study aims to determine the characteristics of the absorption test with SAE 10W-30 and the friction coefficient test with the ASTM D 3702-94 test standard on composite clutch pads made from bamboo powder, coconut powder, glass powder, and copper powder. It is based on the considerations that there are abundance of natural resources of bamboo and coconut with that is still not optimally utilized as well as the discovery of several hazardous clutch lining (asbestos) basic material properties. In each test, each composition variation was tested 3 times and from the data, the average value of the composition variation was taken. Based on this research, the specimen with the highest oil absorption value is specimen combination 3 (BB20KL20CU0KC20) with an absorption value of 17.98% and the specimen with the lowest absorption value is specimen combination 2 (BB20KL20CU5KC15) with an absorption value of 4.88%, and the specimen with the highest percentage change in volume is specimen combination 1 (BB20KL20CU10KC10) with a percentage of 3.30%, and the specimen with the lowest percentage change in volume is specimen combination 2 (BB20KL20CU5KC15) with a percentage of 1.01%. From the results of the combined friction coefficient test, specimen 3 (BB20KL20CU0KC20) has the highest friction coefficient value of 0.54526 and specimen 2 (BB20KL20CU5KC15) has the lowest friction coefficient value of 0.16923.
Planejamento didáico em História: uma proposta de plano de aula
Authors: Lima Carollina Carvalho Ramos de
Published: May 2023

Em diálogo com teóricos da Pedagogia Construtivista, da Educação Histórica e dos Letramentos Digitais, propõem-se, neste artigo, um modelo de planejamento didático para aulas de História, aderente às diferentes etapas da Educação Básica.
Para além do conteúdo histórico escolar: as ideias dos alunos sobre a escravização africana e o racismo
Authors: Xavier Erica , Thomsom Ana Beatriz Accorsi
Published: May 2023

Compreendendo a importância de conhecer as direções do tráfico, de onde vieram e para onde foram as populações escravizadas e as contribuições culturais trazidas por estes povos (SOUZA, 2009), este trabalho busca apresentar experiência desenvolvida no oitavo ano do ensino fundamental II, através do projeto intitulado “As viagens de africanos escravizados e a travessia do Atlântico”. O intuito foi despertar na consciência dos alunos um sentido histórico capaz de estabelecer relações entre presente, passado e futuro (RÜSEN, 2015a) sobre a ideia de superioridade racial. Buscamos propor uma educação histórica humanizada, empática, que ultrapassasse a noção de conteúdo escolar tornando-se uma orientação para vida prática. Foram desenvolvidas pesquisas supervisionadas sobre de onde os africanos escravizados partiram, onde desembarcaram na América, as condições e as resistências em torno da escravização. O projeto foi desenvolvido com base na metodologia conhecida como “aula oficina” a partir da proposta da pesquisadora Isabel Barca (2004).
A arte contemporânea guineense: quase cinco décadas de arte na Guiné-Bissau e na Diáspora. Qual é o próximo passo?
Authors: Levi Joseph Abraham
Published: May 2023

Neste estudo analisar-se-ão as obras produzidas por alguns artistas plásticos contemporâneos a viverem na Guiné-Bissau e na Diáspora guineense com particular atenção dada aos géneros artísticos por eles usados assim como à sua mensagem sociopolítica. Após uma breve introdução às diferentes formas de arte plástica oriundas da Guiné-Bissau e da Diáspora guineense, concentrar-nos-emos em alguns artistas plásticos para desconstruirmos a sua produção artística e, contemporaneamente, analisarmos o seu conteúdo criativo-social.
Contribuições do GeoGebra para o Ensino de Funções: o que revelam algumas pesquisas brasileiras
Authors: Leite Antonio Carlos Pereira , Miola Adriana Fátima de Souza
Published: May 2023

O presente artigo teve, como objetivo, analisar as contribuições do GeoGebra para o ensino e a aprendizagem de funções nas pesquisas brasileiras. Para isso, optamos pela metanálise como metodologia de pesquisa por meio de uma abordagem qualitativa. Realizamos uma busca na Biblioteca Digital Brasileira de Teses e dissertações (BDTD) e encontramos 43 pesquisas referentes à utilização do GeoGebra como ferramenta para o ensino de funções e, dentro desse conjunto, encontramos 34 pesquisas desenvolvidas na Educação Básica e 9 (nove) pesquisas na Formação Inicial de professores. As pesquisas no conjunto que envolvem a Educação Básica mostraram resultados bastante significativos com a utilização do GeoGebra no ensino de funções, destacando-se, principalmente, o dinamismo, os recursos visuais como facilitadores para que esses conteúdos sejam assimilados pelos estudantes e para serem propostos pelos professores. Dentro do subconjunto referente ao ensino superior, identificamos apenas uma pesquisa com professores do curso em licenciatura em Matemática e as demais pesquisas foram realizadas com estudantes licenciandos de curso de Matemática e revelam que a utilização do GeoGebra em sala de aula traz dinamismo e facilita a realização de atividades investigativas e a exploração e visualização de propriedades.
Paulo Freire nas licenciaturas do IFMG
Authors: Ferreira Tamires Vilela , Duque Thais Oliveira
Published: May 2023

O presente artigo tem como finalidade investigar a presença ou ausência de Paulo Freire nos cursos de licenciatura ofertados no Instituto Federal de Minas Gerais (IFMG). Para cumprir o objetivo da pesquisa, o caminho metodológico foi pautado inicialmente na análise dos Projetos Pedagógicos dos Cursos (PPC's), tendo sido utilizada a análise de conteúdo para estruturar as fases de análise do documento. Posteriormente, foi enviado um questionário com possíveis formandos dos cursos de Licenciatura do IFMG, como instrumento de coleta de dados deste projeto. Após a análise dos PPC's, a presença de Freire foi constatada tanto de forma explícita como implícita, sendo que o maior número de aparições foi através de citações que remetem a ideias do educador, mas sem mencioná-lo. No questionário, nota-se que os licenciandos conhecem Paulo Freire, e aqueles que não o conhecem estão de acordo com sua pedagogia. Alguns casos isolados de críticas ao educador foram percebidos, mas a grande maioria reconhece a importância de Freire para a educação. Constatou-se que a aderência a Paulo Freire pela maioria dos licenciandos é satisfatória, mas que deve ser mais explorada, concluindo que os cursos de licenciatura, da instituição investigada, utilizam de forma rasa da pedagogia freireana.
Clinical Characteristics of Shocks in Patients with implanted cardioverter defibrillator Following COVID-19 Infection
Authors: sun Jianying , Ma Juan , Wei Feiyu , Ma Yazhe , Zhang Xi , Gao Xiaolong , Ma Tao , Guo Jia , Li Xiuhua , Fan Jie
Published: May 2023

Background and Aims: The relationship between SARS-CoV-2
infection and ICD shock remains unclear. We analyzed the characteristics
of patients received shocks after SARS-CoV-2 infection to explore causes
of these shocks to provide information for subsequent treatment.
Methods: We retrospectively analyzed data from seven patients
who hospitalized the First People’s Hospital of Yunnan Province between
December 2022 and January 2023 after experiencing ICD shock or
ventricular arrhythmias following SARS-CoV-2 infection. We collected
baseline information i.e., age and sex, device type, arrhythmia type,
comorbidities, etc to analyze the causes of electrical shocks.
Results: All patients’ devices were implanted in our hospital.
The patients’ mean age was 67±10 years. Four underwent implantation for
primary prevention, and three for secondary prevention. These patients
received 80 ICD shocks after SARS-CoV-2 infection, 71 (88.75%) nine
(11.25%) of which were treatment for ventricular tachycardia and atrial
fibrillation, respectively. There were 54 antitachycardia pacing(ATP)
treatments, which forty-eight arrhythmic events were terminated through
antitachycardia pacing and six not. Laboratory tests conducted upon
admission revealed that six patients had blood potassium levels below
4.0 mmol/L. Five patients had blood calcium levels below 2.11 mmol/L.
Four of seven patients had elevated troponin concentrations
(0.030–0.297 ng/mL). All patients had significantly elevated N-terminal
pro-B-type natriuretic peptide levels (608.8–25,758 pg/mL). Six
patients had a QT interval of > 440 ms and a mean QT
interval of 460±46 ms. Conclusion: SARS-CoV-2 infection may be
associated with ICD shock. Clinicians should pay close attention to
patients with implanted devices after SARS-CoV-2 infection and actively
eliminate arrhythmogenic triggers to minimize the likelihood of ICD
shock.
Analysis of Prognostic Factors and Development of Nomogram Model for Predicting the Prognosis of Children with Secondary Hemophagocytic Lymphohistiocytosis
Authors: Du Zuochen , Luo Nandu , Zhang Pingping , Yang Guangli , Li Baoli , Shen Yanjiao , Shi Xiaoqi , Cao Xiuli , Huang Jiaojiao , CHEN YAN , Huang Pei
Published: May 2023

Objective: To establish a prediction Nomogram based on
prognostic factors for children with hemophagocytic lymphohistiocytosis
(HLH). Methods: A retrospective analysis of pediatric HLH cases
diagnosed at the Affiliated Hospital of Zunyi Medical University between
January 2012 and December 2022 was conducted. Cox regression analysis
was used to identify prognostic factors for pediatric HLH patients. The
C-index, ROC curve, and AUC were used to evaluate the discrimination of
the model. The DCA was used to evaluate the clinical application value
of the model. Results: A total of 133 cases of secondary
pediatric HLH patients were included in this study, with 45 deaths and
88 survivors. Univariate analysis showed that age ≤ 2 years, PLT ≤ 50×10
/L, HB ≤90 g/L, AST ≥ 200 U/L, CK-MB ≥ 50 U/L, LDH ≥
1000 U/L, SF ≥1500 μg/L, PT ≥ 20 s, APTT ≥ 40 s, hypoalbuminemia,
hypofibrinogenemia, mechanical ventilation, splenomegaly, ARDS,
respiratory failure,CNSL, shock, DIC, pulmonary hemorrhage, and
gastrointestinal bleeding are risk factors for the survival of those
secondary pediatric HLH patients ( P <0.05), while
blood purification therapy may be a protective factor for HLH prognosis
( P = 0.049). Multivariable Cox showed that CNSL (HR = 3.18,
95%CI = 1.72-5.89), PLT ≤ 50×10^9/L (HR = 2.16, 95%CI = 1.11-4.19),
hypoalbuminemia (HR=2.65, 95%CI=1.14-5.17), and hypofibrinogenemia (HR
= 2.48, 95%CI = 1.19-5.14) were independent risk factors for the
outcome of children with HLH, while the use of blood purification
therapy (HR = 0.32, 95%CI = 0.16-0.64) was an independent protective
factor. A Nomogram prediction model was constructed using R software,
and the ROC curve , C-index, and calibration curve showed good
discrimination and fit of the model. The DCA curve showed that the model
had good clinical applicability. Finally, based on the Nomogram score
and HR value, the subjects were divided into three groups, and it was
found that the mortality rate in the high-risk group was significantly
higher than that in the low-risk group. Conclusion: The
development of a Nomogram to predict the prognosis of secondary
pediatric HLH patients has good discrimination and accuracy and may have
good clinical application value.
Expansion of national laboratory capacity in the Federal Republic of Somalia throughout the COVID-19 pandemic
Authors: Mohamed Sahra , Mohamed Ayni , Abukar Hassan , Sheikh Abdulrahman
Published: May 2023

Abstract Introduction Somalia faced significant COVID-19 exposure due to
limited lab capacity for pathogen detection. The country’s healthcare
system is strained by poverty, conflict, malnutrition, and outbreaks.
Urgent action was required to enhance COVID-19 detection, save lives,
and support nationwide vaccination and healthcare efforts. Methods With
WHO and other partners, the Ministry of Health formed the COVID-19
incident management committee to address infections. Testing was
initiated at the National Public Health Laboratory, and through training
and investment, expanded to 11 additional sites. Genomic surveillance
was established to monitor circulating genotypes. A comprehensive data
management system was implemented to track infections from patient to
reporting, ensuring effective monitoring and response. Results The
enhanced laboratory capacity identified 26,439 confirmed SARS-CoV-2
cases, resulting in 1,361 deaths and a case fatality rate (CFR) of
5.15%. A total of 344,002 suspected samples were tested within the
country. Genomic surveillance was initiated in March, 2022, and the
first results were reported in Agoust, 2022. The e-SPAR tool assessment
demonstrated a significant improvement in laboratory capacity, rising
from 27% in 2018 to 56% in 2021, marking an overall improvement of
210%. Discussion Somalia has made notable strides in enhancing and
expanding in-country molecular diagnostic capacity, enabling swift
COVID-19 diagnosis. This capacity is being expanded to encompass other
pathogens as part of an integrated disease surveillance program. The
objective is to enhance response capabilities to emerging pathogen
outbreaks. The implementation of a data management system has improved
data monitoring and evaluation, serving as a crucial foundation for Labs
Individual genotypes from environmental DNA: fingerprinting snow tracks of three large carnivore species
Authors: Barba Marta De , Baur Molly , Boyer Frédéric , Fumagalli Luca , Konec Marjeta , Miquel Christian , Pazhenkova Elena , Remollino Nadege , Skrbinšek Tomaž , Stoffel Céline , Taberlet Pierre
Published: May 2023

Continued advancements in environmental DNA (eDNA) research have made it
possible to access intraspecific variation from eDNA samples, opening
new opportunities to expand non-invasive genetic studies of wild animal
populations. However, the use of eDNA samples for individual genotyping,
as typically performed in non-invasive genetics, still remained
unachieved. We present the first successful individual genotyping of
eDNA obtained from snow tracks of three large carnivores: brown bear
(Ursus arctos), European lynx (Lynx lynx) and wolf (Canis lupus). DNA
was extracted using a protocol for isolating water eDNA and genotyped
using amplicon sequencing of short tandem repeats (STR) and, for brown
bear, a sex marker, on a high-throughput sequencing platform. Individual
genotypes were obtained for all species, but genotyping performance
differed among samples and species. Multilocus genotyping success for
individual identification was higher for brown bear samples (6 over 7),
than for wolf (7 over 10) and lynx (4 over 9) samples. The sex marker
was genotyped in 5 out of 7 brown bear samples. Results for three
species show that reliable individual genotyping, including sex
identification, is now possible from eDNA in snow tracks, underlining
its vast potential to complement the non-invasive genetic methods used
for wildlife. To fully leverage the application of snow track eDNA,
improved understanding of the ideal species- and site-specific sampling
conditions, as well as laboratory methods promoting genotyping success
are needed. This will also inform efforts to retrieve and type nuclear
DNA from other eDNA samples, thereby advancing eDNA–based individual
and population level studies.
Head and neck squamous cell carcinoma of unknown primary - Who can be offered surgery as the sole treatment modality? A systematic review
Authors: Takhar Arunjit , Wilkie Mark , Srinivasan Devraj , King Emma
Published: May 2023

Objective Evaluate the role of neck dissection (ND) as the sole
treatment modality for patients with cervical head and neck squamous
cell carcinoma of unknown primary (HNSCCUP). Design Systematic
review of observational cohort studies with qualitative synthesis.
Setting PubMed, Ovid EMBASE, and Cochrane Controlled register
of Trials (CENTRAL) were screened from January 2000 up to October 2021.
Participants HNSCCUP patients undergoing ND. Main
Outcome Measures The primary outcome was 3-year overall survival (OS).
Secondary outcomes included disease-free survival (DFS), primary
emergence, regional recurrence, and distant metastasis. Results
Fourteen eligible studies were identified, including 1,780 patients, of
whom 294 received ND as their sole treatment (seven studies) with 3-year
OS ranging from 43.9% to 100%. 3-year DFS was reported in four studies
(n=62) ranging from 42.8% to 67.0%. 5-year OS and DFS were available
in three studies (n=31), ranging from 36.6% to 75.0%, and 43.6% to
67.0%, respectively. The rate of primary emergence ranged from 11.1%
to 33.3% (seven studies, n=157), regional relapse from 0.0% to 50.0%
(five studies, n=60), and distant metastasis from 0.0% to 3.3% (three
studies, n=45). Patients undergoing ND as a sole treatment had
predominantly p16 positive N1 (TNM7) disease without ECS.
Conclusion Outcomes for HNSCCUP patients undergoing ND alone
range widely in the literature but appear reasonable in a subset of
patients with early stage p16 positive disease. Data is lacking for p16
negative disease where the potential primary site is more varied and
primary emergence appears more common.
The Steady States of Antitone Electric Systems
Authors: Comanescu Dan
Published: May 2023

The steady states of an antitone electric system are described by an
antitone function with respect to the componentwise order. When this
function is bounded from below by a positive vector, it has only one
fixed point. This fixed point is attractive for the fixed point
iteration method. In the general case, we find existence and uniqueness
results of fixed points using the set of P-matrices.
Time-energy consumption optimal path-constrained trajectory planning of excavator robotics
Authors: Zhang Yunyue , Sun Zhiyi , Sun Qianlai , Wang Yin
Published: May 2023

During the cyclic operation process of hydraulic excavators, based on
manual experience, issues such as low work efficiency and high energy
consumption can cause significantly high wearing of the joints of the
excavator; this markedly affects the service life of the excavator. To
solve such issues, we propose a secondary trajectory optimization method
based on time–energy consumption that enables the excavator to conduct
smooth, efficient, and low-energy-consumption work. Considering
different weight coefficient values and obtaining the optimal
time–energy trajectory, we compare the above-mentioned results with
those obtained through skilled manual operation of hydraulic excavators.
The experimental results demonstrate that through reasonable and
effective planning of each joint movement, the large jerk that occurs
during joint movement processes may be effectively avoided, the working
efficiency of the excavator is improved, unnecessary energy consumption
is reduced, and the excavator can operate autonomously under stable
conditions. These results verify the effectiveness and feasibility of
the proposed method.
TRIAL OF A MULTI-COMPONENT PROGRAM TO IMPROVE THE EFFECTIVE USE AND MAINTENANCE OF SELECTED MEDICAL EQUIPMENT IN A LOW-RESOURCE SETTING
Authors: JLP Chaminda , PVDS Dharmagunawardena , Rohde Alexia , Kularatna Sanjeewa , Hinchcliff Reece
Published: May 2023

Background: Medical equipment (ME) maintenance retains an
asset’s original anticipated useful life and preserves its reliability
and cost-effectiveness. This study developed and trialled a
multi-component program to improve ME maintenance in nine Sri Lankan
hospitals. Methods: This pre-post study involved an initial
baseline assessment of existing ME maintenance systems in nine
hospitals, the development and implementation of a multi-component
improvement program, and a three-month post-evaluation. Five target ME
were selected for the study: oxygen regulators, electrocardiogram (ECG)
machines, suction apparatus, blood pressure (BP) apparatus and mini
autoclaves. A validated questionnaire of randomly selected nursing
officers (n=101) and healthcare assistants (n=120) was used to obtain
baseline ME maintenance data. Six focus groups and 24 interviews were
conducted with key stakeholders to co-design the multi-component
interventions, which included: developing a standard operating procedure
(SOP) targeting preventive maintenance activities; establishing focal
points to provide technical and logistic support; staff training; and
the introduction of institutional ME maintenance documents. Program
effectiveness was assessed at three months post-implementation.
Results: Baseline assessment identified no ME maintenance
programs implemented in any of the hospitals. Following program
implementation, improvements were noted in: the availability
(p<0.05) and functional level (p<0.05) of all
selected ME; equipment maintenance processes (p=0.000); as well as staff
knowledge, skills, perceptions and satisfaction. Conclusions:
The program improved the use and maintenance of ME and was widely
supported by key stakeholders. The approach is likely relevant to other
resource-poor hospital settings where inadequate ME maintenance causes
health system inefficiencies.
Title of Manuscript: Increase in national health insurance during the COVID-19 pandemic in Peru.
Authors: Zumarán-Nuñez Carlos J. , Gil-Olivares Fradis , Navarro Mauro Huamani , Herrera Evelyn Pasache , Alva-Diaz Carlos , Huerta-Rosario Mariela , Valle Jose Miguel Arca Gonzales del
Published: May 2023

Increasing health insurance has been a challenge during the pandemic in
developing countries. For this reason, we analysed the regulations
issued by the Peruvian government about health insurance and the health
insurance affiliation at the national level during the pandemic. We
carried out a cross-sectional study that included a review of national
government regulations and an analysis of secondary data on people
enrolled in health insurance. We identified eight national regulations
oriented to foster health insurance from the last quarter of 2019 to the
third quarter of 2021. We also found an increase in health insurance
coverage at the national level, represented by insurer organisations:
Comprehensive Health System (SIS) (72.5%), Social Security (ESSALUD)
(27.6%), Private Insurers (2.7%), Armed Forces/Police’s insurer
(1.9%), and other insurer companies (6.2%). The affiliation increased
mainly in quintile 5 (23.4%) and quintile 4 (20.2%). During the
pandemic, there have been developed and implemented regulations that
have promoted health insurance at the national level; likewise, we found
an increase in the number of enrolled people, with the greatest increase
in the SIS.
Can Private Health Insurance Reduce the Incidence of Household Catastrophic Health Expenditure in China?
Authors: Li Xiao , Shi Long , Chen Jun , Liao Zangyi
Published: May 2023

Private health insurance is an important part of China’s multilevel
medical security system, which is conducive to improving the medical
security level of insured households. Based on Chinese General Social
Survey (CGSS) data, this study uses a logit model to estimate the impact
of private health insurance on household catastrophic health
expenditure. Our research results show that private health insurance can
significantly reduce the incidence of catastrophic household health
expenditure. Using the instrumental variable method to weaken the
endogenous problem and the propensity score matching method to control
the self-selection problem, the research conclusion is still valid. In
terms of heterogeneity, private health insurance has a greater impact on
reducing the incidence of catastrophic health expenditure in rural and
non-elderly households. The mechanism test shows that health performance
plays an intermediary role between private health insurance and
catastrophic household health expenditure. This study suggests that the
Chinese government should accelerate the development of private health
insurance, expand its coverage of private health insurance, and reduce
the incidence of catastrophic health expenditure in households.
Extending the scope of telemedicine to Podiatric Medicine
Authors: Formosa Cynthia , Mercieca Lisa , N Chockalingam , Cassar Vincent
Published: May 2023

Introduction: The adoption of telemedicine within the
healthcare industry has experienced a surge in momentum as a result of
the exceptional circumstances brought about by the COVID-19 pandemic.
The present study sought to explore the views of different stakeholders
regarding the feasibility of introducing telemedicine for foot and ankle
management delivered in a primary care context. Method: A
mixed-methods approach was adopted, wherein the main source of data
collected was quantitative, consisting of online questionnaires.
Additionally, focus groups and interviews were conducted to corroborate
the findings obtained from the questionnaires. Results: An
agreement between patients, podiatrists, and senior healthcare
management was reached regarding the introduction of a telemedicine
service for foot and ankle management. Proposed measures entail the
establishment of a comprehensive evidence-based framework and standard
operating procedures for both users and providers, the provision of
appropriate training and professional development opportunities for
healthcare practitioners, and enhanced community education and outreach
initiatives aimed at raising awareness about the scope, beneficiaries,
and modalities of this service. Discussion: This research has
highlighted the need for the introduction of telemedicine services for
foot and ankle care management. Impromptu interventions due to the
pandemic were executed without adequate evidence-based guidelines for
healthcare professionals to follow. This unforeseen situation created a
favourable opportunity for further research and to reconsider what
measures are necessary to determine appropriate guidelines and training
for the introduction of this service.
Palmitoylation of Tetraspanin CD82 Is Required for Its Biological Activities of Anti-apoptosis in Breast Cancer
Authors: Zhang Yu , He Shuiqing , Bu Jingya , Zhang Mingzhe , Zhang Yihuan , Yu Yaning , Wang Xiaodan , Li Ying
Published: May 2023

Background: CD82/KAI-1 which is a member of the tetraspanin superfamily,
has been proposed to exert its activity via the Tetraspanin Web.
However, the mechanism of CD82 palmitoylation in this web has not been
fully elucidated. The purpose of this study is to investigate cell
migration and apoptosis by mutation of tetraspanin CD82 palmitoylation.
Methods: This study elucidated the impact of various palmitoylation site
mutations on apoptosis in breast cancer cells through a comprehensive
approach involving RT-PCR, Western blotting, TUNEL assay,
immunofluorescence, and tumor formation assay in athymic nude mice
model. Results: We found that the mutation of CD82 palmitoylation at
cys74 and cys83 or cys5 and cys74 and cys83 simultaneously increased
apoptosis in breast cancer. However, the other forms of mutation of CD82
palmitoylation showed no effects on apoptosis. Conclusion: The study
strongly implicate that CD82 palmitoylation at cys74 and cys83 are both
closely related to maintain biological function.
Dietary Composition of Black-necked Crane (Gruidae: Grus nigricollis) from the Winter Habitat in Bumdeling, Trashiyangtse District: an insight from the fecal analysis
Authors: Wangchuk Jigme , Sherub Sherub , Tenzin Ugyen , Tshering Tshethup , Wangdi Karma , Drukpa Sangay , Chophel Tshering , Wangmo Ugyen , Tshering Jigme
Published: May 2023

Every living organism requires a space for shelter, water and food to
successfully complete their life history processes. Changes in foraging
and roosting habitats have an impact on Grus nigricollis interaction
with the ecosystem in which they live. The choice of habitats by these
birds is mostly influenced by the availability of a variety of food
sources and the security of the environment. Habitat alteration has
endangered the food sources of cranes, leading to a decline in their
population. For better action-based conservation management of cranes’
habitat, it is critical to understand the population and its basis for
nutritional composition. To study the dietary preferences of cranes,
fecal samples were collected from their foraging and roosting sites, and
the content of the feces was examined. Results revealed that paddy
fields were the primary foraging areas and the fecal samples contained
79 identical species from domestic crops, herbaceous plants, and
invertebrates. The dietary composition had no significant variation
across months and sites, but differs significantly in three of the seven
compared localities of roosting and foraging sites with small effect
size. Similarly, fecal dried weight exhibited significant differences
from December-February versus March, suggesting a decline in rice intake
and an increase in invertebrate consumption leading to lower fecal
weight. Dried content in rice feces decreased from December to March.
The presence of domestic food grains after harvest, herbaceous plants,
and invertebrates are crucial components of the habitat structure of
cranes. The presence of domestic food grains after harvest, herbaceous
plants and invertebrates forms critical food structure of cranes.
Amongst arthropods, coleopteran appears to be an important nutritional
food source. Agricultural practices by communities can have a
significant impact on the availability of food sources which must be
promoted those specific grains preferred by cranes.
Disjoint topological transitivity for weighted translations on Orlicz spaces
Authors: Chen Chung-Chuan , Kostic Marko
Published: May 2023

Let G be a locally compact group, and let ? be a Young function. In this
paper, we give a necessary and sufficient condition for weighted
translations on the Orlicz space L?(G) to be disjoint topologically
transitive. In such a way, we continue a great number of recent research
studies considering topological dynamics of operators acting on Lebesgue or
Orlicz spaces of locally compact groups.
Fractional differential equations with maxima on time scale via Picard operators
Authors: Karapınar Erdal , Benkhettou Nadia , Lazreg Jamal , Benchohra Mouffak
Published: May 2023

In this paper, we prove a result of existence and uniqueness of solutions for
the following class of problem of initial value for differential equations
with maxima and Caputo?s fractional order on the time scales: c??a u(?) =
?(?, u(?), max ??[a,?] u(?)), ? ? J := [a, b]T, 0 < ? ? 1, u(a) = ?, We used
the techniques of the Picard and weakly Picard operators to obtain some data
dependency on the parameters results.
Landau-Bloch type theorems of certain subclasses of biharmonic mappings
Authors: Luo Xi , Liu Ming-Sheng , Li Ting
Published: May 2023

In this paper, we first establish a Landau-Bloch type theorem for certain
bounded and normalized biharmonic mappings F(z) = |z|21(z) + h(z), where
1(z) and h(z) are harmonic in the unit disk with |1(z)| ? M1, |h(z)| ? M2.
In particular, our result is sharp when M1 = M2 = 1. Then, we establish
several new versions of Landau-Bloch type theorems for certain normalized
biharmonic mappings with the coefficients condition in place of |h(z)| ? M2
or |1(z)| ? M1, and obtain several sharp results.
New characterizations of weak group matrices
Authors: Zhou Mengmeng , Chen Jianlong , Thome Néstor
Published: May 2023

In this paper, we prove that a complex square matrix is weak group matrix if
the m-th power of this matrix commutes with its weak group inverse, where m
is an arbitrary positive integer. Firstly, some new characterizations of
weak group matrices are investigated by means of core-EP decomposition.
Secondly, we study new equivalent conditions of the weak group matrix by
using commutator and rank equalities. Finally, the relationships between {m,
k}-core EP matrices, k-EP matrices and weak group matrices are given.
Confidence ellipses for simple regression parameters with strongly mixing errors
Authors: Elmoumen Abdelkader , Zerouati Halima , Dahmani Abdelnasser
Published: May 2023

In this work, we establish exponential inequalities which allow us to
construct confidence regions, characterized by ellipses, for the least
squares estimates of the parameters in the case of a linear regression model
with ?-mixing errors.