bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI HUKUM PIDANA TERHADAP TINDAKAN BULLYING DAN CYBERBULLYING
Authors: Agastya Dwi Wijaya  , Ahmad Heru Romadhon  , Sudjiono
Published: August 2024

Bullying dan cyber bullying merupakan pelanggaran terhadap norma kesopanan dan norma kemanusiaan karena telah melanggar HAM. Adanya kejadian perundungan media sosial (Cyberbullying) dengan siswa SMA dan berlanjut mengakibatkan perundungan secara langsung (bullying) yang mengakibatkan timbulnya tindak pidana kekerasan. Tujuan dari penelitian ini ialah guna mengetahui hambatan dan pemecahan masalah terhadap tindakan bullying dan cyberbullying yang diberikan oleh pihak Kepolisan Polrestabes Surabaya. Metode penelitian yang diterapkan adalah penilaian kualitatif dengan jenis Yuridis Normatif dan Yuridis Empiris, menggunakan pendekatan Undang-undang (Statute Approach). Penelitian ini menggunakan data primer dan data sekunder sebagai sumber bahan hukum. Teknik pengumpulan data meliputi observasi, wawancara, dan studi kepustakaan yang dilakukan di Polrestabes Surabaya. Hasil yang didapat adanya kasus bullying yang terjadi Di Surabaya, terjadi kasus bullying antara siswi SMA kelas XI sebagai pelaku terhadap siswi kelas X sebagai korban di tempat umumnya pada akhir Januari 2024. Polrestabes Surabaya telah menangani kasus ini secara langsung. Berdasarkan penelitian di Polrestabes Surabaya, hambatan terhadap penanganan bullying dan cyberbullying meliputi keterbatasan personel internal serta kurangnya dukungan aktif masyarakat sebagai faktor eksternal. Polrestabes Surabaya mengatasi masalah ini dengan meminta bantuan personel dan sarana prasarana dari Polda Jawa Timur, serta melakukan mediasi dan sosialisasi di sekolah dan masyarakat Surabaya.
PENEGAKAN HUKUM TERHADAP PELANGGARAN MODIFIKASI KNALPOT RACING PADA SEPEDA MOTOR DI KOTA SURABAYA
Authors: Achmad Ony Mirza Firdiansyah  , Ahmad Heru Romadhon  , Agam Sulaksono
Published: August 2024

Penegakan hukum terhadap penggunaan knalpot racing di Kota Surabaya telah terbukti efektif melalui Operasi Patuh Semeru yang dilakukan oleh Kepolisian Resor Kota Surabaya. Razia ini dilakukan sebagai respons terhadap keluhan masyarakat mengenai gangguan kebisingan knalpot modifikasi. Metode penelitian yang digunakan adalah penelitian empiris untuk mengumpulkan data deskriptif analitis. Penegakan hukum didasarkan pada Undang-Undang Nomor 22 Tahun 2009 Tentang Lalu Lintas dan Angkutan Jalan, terutama Pasal 285 ayat (1), serta surat telegram Kapolri ST/1045/V/HUK.6.2./2021 yang mengatur penggunaan alat pengukur suara saat penindakan. Kepolisian telah melaksanakan penilangan knalpot racing dengan menggunakan sound level meter atau desibel meter. Upaya penegakan hukum mencakup strategi pre-emptif melalui pembinaan dan penyuluhan, serta upaya preventif dengan patroli rutin untuk mencegah pelanggaran. Upaya represif dilakukan dengan menindak pelanggar sesuai peraturan yang berlaku. Faktor penghambat meliputi kualitas penegak hukum, serta sarana dan prasarana yang tersedia.
Water Security Characteristics of Existing Water Service Provision Systems in Informal Settlements within Nairobi County, Kenya
Authors: Ogaro Lugard Kaunda , Omuterema Stanley , Neyole Edward
Published: August 2024

Attainment of water security in urban informal settlements in developing countries can be a complex undertaking due to various factors that affect water service provision, such as insufficient water quantities, unreliable water supply, aging pipes, and infrastructure coverage, among others. In addition to this, the territorial behaviour and therefore a siloed approach of service providers propagate water insecurity. This situation has an impact on the socio-economic development, peace and political stability, water-related disasters, and waterborne diseases in many urban informal settlements in developing countries. The study sought to assess water security characteristics in informal settlements in Nairobi County. The research was informed by the systems theory. The study adopted a descriptive research design. The research targeted a population of 2,511,991 people living in the informal settlements and 544 water service providers (formal utilities and small-scale vendors) operating in the informal settlements. Both probabilistic and non-probabilistic sampling methods were used in this study to select the respondents. Data was collected from a sample of 388 households and 62 water vendors from nine slums in 12 sub-counties. A household questionnaire was used to collect data. Data was analysed using descriptive and inferential statistics. From the findings, only 0.4% of households met all six parameters (availability, access, quantity, quality, affordability, and reliability) of water security. Most of the households satisfied four parameters, 30% met three parameters, 20.8% met two parameters, 11.7% met five parameters, and 5.3% met one parameter. This pointed to a situation where water security is a major concern in Nairobi’s Informal Settlements (INSEs). The existing water structures of service provision influenced only three of the six water security factors, and that is, availability, access, and quality. The level of structure did not have any impact on quantity, affordability, or reliability of water services. The study therefore concludes that the provision of infrastructure alone may not necessarily lead to overall household water security. The research findings show that integration is possible along the three levels—water production, water delivery infrastructure, and service levels experienced by the households. It was however noticed that a household could depend on multiple sources and therefore experience various levels of services. The study recommends that the national and county governments and stakeholders in the water sector, while planning water service provision and infrastructure development, should ensure that efforts towards attaining universal access to water through availability, access, quantity, quality, affordability, and reliability should have a targeted approach to reach those who are most water insecure.
DESAFIOS NO CUIDADO DE IDOSO PORTADOR DE ESCLEROSE LATERAL AMIOTRÓFICA: RELATO DE EXPERIÊNCIA
Authors: Veloso Moisés de Sousa , Silva Filho Joais Alexandre da , Alencar Álvaro Henrique Andreatta , Dantas Rebeka Daiany Duarte , Lima Daiana Magno Amaral
Published: August 2024

A esclerose lateral amiotrófica (ELA) trata-se de um distúrbio neurodegenerativo que desencadeia aumento do tônus muscular e fraqueza progressiva dos membros. Desse modo, o presente trabalho teve como objetivo destacar os principais aspectos que permeiam o cuidado a esse público, buscando propiciar a melhor qualidade de vida. Ademais, trata-se de um estudo descritivo com abordagem qualitativa, do tipo relato de experiência, pautada nas experiências de vivência acadêmica de um grupo de estudantes de medicina em uma ação de saúde realizada na microárea de uma Estratégia Saúde da Família (ESF), em Redenção-PA, pautada na criação de propostas de enfrentamento dos desafios existentes nos cuidados a um idoso portador de ELA. Diante disso, elaborou-se uma ação pautada no fomento de uma consciência plena entre os responsáveis pelos cuidados, objetivando estabelecer a compreensão das limitações psíquicas do paciente e cônjuge, bem como formalizar a conscientização da importância da divisão de tarefas e efetivação da garantia de amparo emocional para promover o amplo cuidado. Assim, foi notório a relevância de tal projeto para buscar garantir uma atenção holística, visando melhorar o bem-estar e a qualidade de vida dos pacientes.
FORMAÇÃO EM EDUCAÇÃO AMBIENTAL COMO PRÁTICA EDUCATIVA NA EDUCAÇÃO PROFISSIONAL TECNOLÓGICA
Authors: Silva José Antonio Souza da , Vinholi Júnior Airton José
Published: August 2024

Este artigo teve por objetivo discutir a educação ambiental como prática educativa em consonância com a formação de professores na educação profissional e tecnológica (EPT). Permeando a legislação vigente, foi possível analisar que os instrumentos para a aplicabilidade dessa prática têm respaldo legal, bem como para a formação dos docentes. A educação ambiental está presente no cotidiano da sociedade como um todo, no entanto, para formar um cidadão efetivamente crítico, reflexivo e ativo na sociedade, que saiba discutir os problemas socioambientais, é fundamental que este possua formação, e esta começa pelos professores, como preconiza a lei. A educação ambiental não deve ser aplicada em forma de disciplina, mas de maneira interdisciplinar e contextualizada. É uma temática atual e complexa, porém, fundamental para a formação de um cidadão crítico e ativo na sociedade capitalista, que impõe uso irracional dos recursos naturais e consumo exagerado de bens manufaturados. Neste trabalho, de enfoque qualitativo, foi utilizada a metodologia de pesquisa bibliográfica. Para que ocorram práticas docentes efetivas, é preciso que tais profissionais tenham formação em educação ambiental, pois, assim, eles poderão mudar as suas práticas educativas utilizando metodologias inovadoras, e não tradicionais.
THE MICROBIAL LANDSCAPE OF PHARYNX AND ITS CHANGES IN POST-COVID PERIOD
Authors: E. I. Salivonchik , E. A. Dotsenko , D. P. Salivonchik , N. V. Yarets , A. S. Savenkova , M. V. Sholkava
Published: August 2024

Introduction. The microbial landscape of a pharynx at the period of COVID-19 pandemic, compared to the pre-Covid period, have a great practical and scientific importance. Purpose. We determine the microbial landscape in patients with pharyngitis during the pandemic of the new coronavirus infection COVID-19 and the dynamics of antibiotic resistance of the most common types of microorganisms in comparison with the “pre-Covid” period. Materials and methods. We estimated 403 samples of throat culture from patients with pharyngitis. The main group consists of 308 samples from patients during the COVID-19 pandemic (2020-2022 years). The comparison group consists of 95 samples taken in 2019 year. Results. We reveal the following features of throat culture: Gram-positive flora, mainly S. aureus, decreases by 2 times, and Candida spp. increases by 2 times in patients with pharyngitis during the COVID-19 pandemic, compared with the pre-Covid period, p< 0.05. Kl. pneumonia slightly increases up to 18% in 2020. Enterococcus spp, on the contrary, had a slow but steady trend towards an increase from 5% in 2019 to 12% in 2022 (p>0.05), which may indicate the development of pharyngeal dysbiosis that occurs during treatment of COVID-19 infection. Throat culture bacteria increase resistance to semisynthetic penicillins: S.aureus from 4% to 12-30% (p<0.05), Klebsiella pneumoniae from 33% in 2019 to 54% in 2021 (p<0.05), with a subsequent decrease to 28% in 2022. Klebsiella pneumoniae also increases resistance to fluoroquinolones from 25% in 2019 to 40% in 2021 (p<0.05).
ENVIRONMENTAL CONSEQUENCES OF GLOBAL ENERGY: NON-RENEWABLE ENERGY SOURCES
Authors:   Belarusian State Medical University, I. N. Semenenya , V. A. Pereverzev ,   Belarusian State Medical University
Published: August 2024

The article provides a brief overview of the main information on the negative impact on the environment and human health of non–renewable natural energy resources currently used in the world - oil, coal, gas, oil shale, peat, uranium. A brief general description of the relevant sources of industrial energy, the world reserves of these energy resources, their production volumes, and distribution across different countries is given. It is noted that there is a need to change the structure of the global energy balance and search for fundamentally new approaches to the development of environmentally safe and highly efficient energy sources to fully meet all the needs of mankind.
The Critical Number and Size of Precipitation Embryos to Accelerate Warm Rain Initiation
Authors: Lim Jung-Sub , Noh Yign , Lee Hyunho , Hoffmann Fabian
Published: August 2024

Abstract. Understanding warm rain initiation through droplet collision and coalescence is a fundamental yet complex challenge in cloud microphysics. Although it is well-known that sufficiently large droplets, so-called precipitation embryos (PEs), may accelerate droplet collisions, it is uncertain how many and how large these PEs should be to affect rain initiation substantially. We address this question using an ensemble of box simulations with Lagrangian cloud microphysics. We found that the warm rain initiation is substantially accelerated only if the PE size or number (or the product of those) exceeds a critical threshold necessary to compensate for the PE-induced suppression of collisions among non-PEs. The sensitivity of this threshold to the shape of the droplet size distribution and turbulence effects on the collision process is analyzed. It is shown that more and larger PEs are needed when collisions are already efficient without PEs. Beyond increasing our fundamental understanding of the precipitation process in warm clouds, our results may help to constrain the effect of PE-like particles intentionally or unintentionally added in geoengineering approaches, such as rain enhancement or marine cloud brightening.
Spring-neap tidal cycles modulate the strength of the carbon source at the estuary-coast interface
Authors: Macovei Vlad A. , Rewrie Louise C. V. , Röttgers Rüdiger , Voynova Yoana G.
Published: August 2024

Abstract. Estuaries are dynamic environments with large biogeochemical variability modulated by tides, linking land to the coastal ocean. The carbon cycle at this land-sea interface can be better constrained by increasing the frequency of observations and by identifying the influence of tides with respect to the spring-neap variability. Here we use FerryBox measurements from a Ship-of-Opportunity travelling between two large temperate estuaries in the North Sea and find that the spring-neap tidal cycle drives a large percentage of the biogeochemical variability, in particular in inorganic and organic carbon concentrations at the land-sea interface in the outer estuaries and the adjacent coastal region. Of particular importance to carbon budgeting is the up to 74 % increase (up to 43.0 ± 17.1 mmol C m-2 day-1) in the strength of the estuarine carbon source to the atmosphere estimated during spring tide in a macrotidal estuary. We describe the biogeochemical processes occurring during both spring and neap tidal stages, their net effect on the partial pressure of carbon dioxide in seawater, and the ratios of dissolved inorganic to dissolved organic carbon concentrations. Surprisingly, while the two example outer estuaries in this study differ in the timing of the variability, the metabolic state progression and the observed phytoplankton species distribution, an increase in the strength of the potential carbon source to the atmosphere occurs at both outer estuaries on roughly 14-day cycles, suggesting that this is an underlying characteristic essential for the correct estimation of carbon budgets in tidally-driven estuaries and the nearby coastal regions. Understanding the functioning of estuarine systems and quantifying their effect on coastal seas should improve our current biogeochemical models and therefore future carbon exchange and budget predictability.
A China dataset of soil properties for land surface modeling (version 2)
Authors: Shi Gaosong , Sun Wenye , Shangguan Wei , Wei Zhongwang , Yuan Hua , Zhang Ye , Liang Hongbin , Li Lu , Sun Xiaolin , Li Danxi , Huang Feini , Li Qingliang , Dai Yongjiu
Published: August 2024

Abstract. Accurate and high-resolution spatial soil information is crucial for efficient and sustainable land use, management, and conservation. Since the establishment of digital soil mapping (DSM) and the GlobalSoilMap working group, significant advances have been made in spatial soil information globally. However, accurately predicting soil variation over large and complex areas with limited samples remains a challenge, especially for China, which has diverse soil landscapes. To address this challenge, we utilized 11,209 representative multi-source legacy soil profiles (including the Second National Soil Survey of China, World Soil Information Service, First National Soil Survey of China, and regional databases) and high-resolution soil-forming environment characterization. Using advanced Quantile Regression Forest algorithms and a high-performance parallel computing strategy, we developed comprehensive maps of 23 soil physical, chemical and fertility properties at six standard depth layers from 0 to 2 meters in China with a 90 m spatial resolution (China dataset of soil properties for land surface modeling version 2, CSDLv2). Data-splitting and independent samples validation strategies were employed to evaluate the accuracy of the predicted maps quality. The results showed that the predicted maps were significantly more accurate and detailed compared to traditional soil type linkage methods (i.e., CSDLv1, the first version of the dataset), SoilGrids 2.0, and HWSD 2.0 products, effectively representing the spatial variation of soil properties across China. The prediction accuracy of most soil properties at the 0–5 cm depth interval ranged from good to moderate, with Model Efficiency Coefficients for most soil properties ranging from 0.75 to 0.32 during data-splitting validation and from 0.88 to 0.25 during independent sample validation. The wide range between the 5 % lower and 95 % upper prediction limits may indicate substantial room for improvement in current predictions. The relative importance of environmental covariates in predictions varied with soil properties and depth, indicating the complexity of interactions among multiple factors in the soil formation processes. As the soil profiles used in this study mainly originate from the Second National Soil Survey of China during 1970s and 1980s, they could provide new perspectives of soil changes together with existing maps based on 2010s soil profiles. The findings make important contributions to the GlobalSoilMap project and can also be used for regional Earth system modeling and land surface modeling to better represent the role of soil in hydrological and biogeochemical cycles in China. This dataset is freely available and can be accessed at https://doi.org/10.11888/Terre.tpdc.301235 (Shi et al, 2024).
An impact-chain-based exploration of multi-hazard vulnerability dynamics: the multi-hazard of floods and the COVID-19 pandemic in Romania
Authors: Albulescu Andra-Cosmina , Armaș Iuliana
Published: August 2024

Abstract. In light of the increased frequency of multi-hazards, the dynamics of vulnerability across time, space, and different hazards emerges as an intriguing but challenging research topic. Within multi-hazard contexts, both the impacts of hazards and mitigation strategies can augment vulnerabilities, adding layers to the complexity of multi-risk assessments. Delving into these interactions, this study aims to analyse new connections in rising vulnerability that result from impacts and adaptation options, as well as their implications, putting co-occurrent powerful river flood events and the COVID-19 pandemic in Romania under the magnifying glass, taking 2020 and 2021 as references. The proposed framework relies on an impact chain that was enhanced to include new elements (i.e. augmented vulnerabilities and derived impacts) and links (i.e. connections that describe the augmentation of vulnerability), which were also used to rank the vulnerabilities based on their augmentation. The impact chain draws on various data and information sources, including the scientific literature, the feedback of first responders, reports, legislative documents, official press releases, and news reports. This research work makes a significant contribution to the field of disaster risk reduction (DRR) by broadening the purpose of the impact chain, transforming it into a first-hand, semi-qualitative tool for analysing vulnerability dynamics.
NILAI PERUSAHAAN: CURRENT RATIO, DEBT TO ASSET RATIO DAN RETURN ON EQUITY MELALUI FINANCIAL DISTRESS
Authors: Edwar Yokeu Bernardin Deden , Rahmawati Cie Tia Nugina
Published: August 2024

The Covid-19 pandemic has had a negative impact on the corporate sector in Indonesia, which could trigger financial difficulties and keep companies away from the attention of investors. This study aims to examine the effect of the Current Ratio, Debt To Asset ratio and Return On Equity on firm value and their impact on Financial Distress at PT Salingka Global Indonesia. The research method used is descriptive verification method with a quantitative approach. The results show that partially the Current Ratio, Debt To Asset ratio, and Return On Equity have a significant effect on Financial Distress but the firm value has no significant effect. Simultaneously the Current Ratio, Debt To Asset ratio and Return On Equity have a significant effect on Financial Distress, but have no effect on firm value
PENGARUH TARIF BEA MASUK, VOLUME IMPOR, DAN NILAI IMPOR TERHADAP PENERIMAAN BEA MASUK
Authors: Rufaidah Fathi , Noviani Dina
Published: August 2024

Penerimaan bea masuk adalah penerimaan negara dari pungutan atas barang impor yang masuk ke Indonesia. Pada tahun 2014 dan 2019 penerimaan bea masuk pada Kantor Pengawasan dan Pelayanan Bea dan Cuka Tipe Madya Pabean A Bandung tidak mencapai target. Penelitian bertujuan mengetahui pengaruh tarif bea masuk, volume impor, dan nilai impor terhadap penerimaan bea masuk pada Kantor Pengawasan dan Pelayanan Bea dan Cukai Tipe Madya Pabean A Bandung. Metode penelitian menggunakan metode deskriptif asosiatif, dengan analisis regresi linier berganda, teknik pengumpulan data menggunakan dokumentasi. Hasil penelitian menunjukkan bahwa tarif bea masuk dan nilai impor berpengaruh positif dan signifikan terhadap penerimaan bea masuk, sedangkan volume impor tidak berpengaruh positif dan signifikan terhadap penerimaan bea masuk. Secara simultan tarif bea masuk, volume impor, dan nilai impor berpengaruh signifikan terhadap penerimaan bea masuk pada Kantor Pengawasan dan Pelayanan Bea dan Cukai Tipe Madya Pabean A Bandung. Diharapkan ada penelitian lanjutan pada penelitian ini dalam mencari faktor lain yang diduga dapat mempengaruhi penerimaan bea masuk dan menambah atau memperluas periode pengamatan.
PELATIHAN DAN PENDAMPINGAN PRODUKTIVITAS PERTANIAN MELALUI HIDROPONIK DI DESA BRONJONG
Authors: Suradji Muchamad , Shoimah Retno Nuzilatus , Arrasyidah Namirah , Pratomo Gilang Setyo , Romadhoni Fajrur
Published: August 2024

This service aims to provide training and community service for agricultural productivity through hydrophonics in Bronjong Village. This dedication is intended to maximize assets in the form of community home gardens to function as productive land with hydrophonic technology. This service uses an Asset Based Community Development (ABCD) approach. The ABCD method has five stages for carrying out the mentoring research process, including: Discovery (Study), Dream (Dream), Design (procedure), Define (Consolidation of Goals), and Destiny (Self Determination). The results of the service carried out by the service and partners in increasing agricultural productivity through the hydrophonic program. This program is important, because it is in line with village programs, one of which is making villages green by empowering people to plant plants in their yards. House yards that are not used become assets that can be used for more productive things, such as hydrophonics. Utilizing this asset is a solution to limited land for planting. Apart from that, the benefits provided by hydrophonic products can later be used for daily needs and can also be used as additional income by selling the crops. In the future, hydrophonics will become one of the icons of a green village if it is implemented en masse by the people of Bronjong village. So, in the future, the farmers of Bronjong Village will inspire smart, sustainable and adaptive farmers.
Efektifitas Metode Resitasi Terhadap Peningkatan Keaktifan Belajar Bahasa Arab
Authors: Naili Tsamrotul Mufidah  , Syaifullah
Published: August 2024

Bahasa Arab merupakan bahasa asing sekaligus bahasa umat islam yang telah lama berkembang di Indonesia. Namun, hingga saat ini terdapat beberapa problem yang harus ditangani dalam proses pembelajarannya terutama dalam penggunaan metode pembelajaran. Adapun metode pengajaran yang digunakan di MA Ma’arif NU Durensewu adalah metode ceramah dimana guru didepan menjelaskan dan siswa hanya mendengarkan. Hal ini tidak begitu efektif dalam pembelajaran terutama dalam meningkatkan keaktifan belajar bahasa Arab siswa MA Ma’arif NU Durensewu. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana dan pengaruh metode resitasi terhadap peningkatan keaktifan belajar bahasa Arab siswa kelas XI MA Ma’arif NU Durensewu Pandaan.
            Metode penelitian yang digunakan peneliti dalam penelitian ini adalah metode kuantitatif. Adapun jenis penelitian yang digunakan adalah pra eskperimen dengan menggunakan desain one group pre-test post-test. Sedangkan instrumen yang digunakan dalam teknik pengumpulan data adalah observasi, tes, dan dokumentasi.
            Dari hasil penelitian menunjukkan bahwa efektifitas metode resitasi terhadap peningkatan keaktifan belajar bahasa Arab memiliki nilai signifikansi tinggi. Hal ini didasarkan pada hasil akhir uji paired sample t-test memiliki nilai signifikansi kurang dari 0,05 yaitu Sig. (0,000) < 0,05 sehingga H0 ditolak, dan Ha diterima. Dalam artian bahwa metode resitasi memiliki pengaruh yang signifikan terhadap peningkatan keaktifan belajar bahasa Arab siswa kelas XI MA Maarif NU Durensewu Pandaan. Hal ini dapat diketahui berdasarkan perbedaan hasil nilai yang signifikan antara sebelum diberikan perlakuan dan setelah diberikan perlakuan menggunakan metode resitasi.
Combined eosinophilic gastroenteritis and ulcerative colitis successfully treated by vedolizumab: a case report
Authors: Takedomi Hironobu , Fukuda Kayoko , Inoue Suma , Tsuruoka Nanae , Sakata Yasuhisa , Aoki Shigehisa , Esaki Motohiro
Published: August 2024

A 47-year-old man with over 10 years’ duration of ulcerative colitis treated by 5-aminosalicylic acid and intermittent topical steroids complained of acute epigastric pain. Esophagogastroduodenoscopy revealed diffuse mucosal edema with patchy redness, multiple erosions and nodularity of the stomach. Bioptic examination revealed marked eosinophilic infiltration, confirming the diagnosis of eosinophilic gastroenteritis. Systemic steroid therapy was initiated, whereas his ulcerative colitis and eosinophilia recurred when tapering the steroid. Addition of azathioprine was ineffective, and we subsequently started vedolizumab for eosinophilic gastroenteritis and ulcerative colitis. The medication effectively improved his abdominal symptoms and esophagogastroduodenoscopy and ileocolonoscopy 1 year later revealed endoscopic improvement of both diseases with histologically decreased level of eosinophilic infiltration. Considering that eosinophils also express α4β7 integrins, vedolizumab can be a possible therapeutic candidate for eosinophilic gastroenteritis as well as ulcerative colitis.
Inhibition of B-cell activating factor activity using active compounds from Physalis angulata in the mechanism of nephrotic syndrome improvement: A computational approach
Authors: Kardani Astrid K. , Fitri Loeki E. , Samsu Nur , Subandiyah Krisni , Endharti Agustina T. , Nugrahenny Dian , Wibowo Syahputra
Published: August 2024

Nephrotic syndrome, a multifaceted medical condition characterized by significant proteinuria, has recently prompted a reorientation of research efforts toward B-cell-mediated mechanisms. This shift underscores the pivotal role played by B-cells in its pathogenesis. The aim of this study was to explore potential therapeutic pathways, with specific attention given to compounds found in Physalis angulata, including withanolides, such as physalins, which constitute one of the five distinct withanolide subgroups identified in Physalis angulata. Furthermore, the study assessed the monoclonal antibody belimumab, designed to target B-cell activating factor (BAFF) and its associated receptors (TACI, BCMA, and BAFF-R). Various research techniques were employed, encompassing data mining, bioactivity analysis, Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) profiling, molecular modeling, and docking studies. Withanolide was demonstrated as a potential inhibitor for the protein BAFF, showing a binding energy of -7.1 kcal/mol. Physalin F emerged as the leading candidate inhibitor for the protein TACI, with a binding energy of -8.3 kcal/mol. Similarly, withanolide was identified as the top inhibitor candidate for the protein BCMA, exhibiting a binding energy of -7.0 kcal/mol. The most favorable interaction with BAFF-R was physalin F, which displayed a binding energy of -8.0 kcal/mol. Moreover, molecular dynamic simulation suggested that physalin F was able to maintain protein stability, hence being a good inhibitor candidate for BAFF-R and TACI proteins. The results of this investigation demonstrated substantial promise, indicating that these withanolides and withaphysalin A compounds derived from Physalis angulata offer alternative avenues for B-cell targeting. Consequently, this study presents opportunities for pioneering treatments in the management of nephrotic syndrome.
«Lectures on Jurisprudence» in the Context of the Development of Adam Smith’s Economic Theory
Authors: Galeev Anton , Chernikov Oleg
Published: August 2024

The contradiction in Adam Smith’s views on human nature, as outlined in his works published during his lifetime, “The Theory of Moral Sentiments” (1759) and “An Inquiry into the Nature and Causes of the Wealth of Nations” (1776), prompted economists to study the development of the ideas of the Scottish economist. Representatives of the Old German Historical School in the mid-19th century were the first to suggest that Smith’s acquaintance with the physiocrats’ ideas during his travels in France significantly influenced his economic theory and explains the differences between “The Theory of Moral Sentiments” and “The Wealth of Nations”. This hypothesis became known as the “French Connection Theory”. Significant development in understanding of the evolution of Smith’s ideas comes from his previously unpublished works. Thus, the lecture notes that Smith delivered as part of his course on moral philosophy at the University of Glasgow were first published in 1896. Those “Lectures on Jurisprudence, Police, Revenue, and Arms” also included the early version of his economic theory. This paper studies the development of Adam Smith’s economic ideas based on the “Lectures on Jurisprudence”. The analysis results in a clearer distinction between Smith’s original ideas and those he drew from physiocrats, thus refining the “French Connection Theory”. The paper shows that even before becoming acquainted with the physiocrats’ theory, Smith formulated the main theses on division of labor, pricing, and critics of the mercantilist system. However, the study confirms a significant influence of the physiocrats on the development of Smith’s theory. The reception of French ideas resulted in formulation of theories of natural value, distribution, and capital in “The Wealth of Nations”. Thus, we cannot completely refute the “French Connection Theory” hypothesis.
The Relationship between Institutional Trust and Online Political Activity
Authors: Tatarko Alexander , Bushina Ekaterina , Mironova Anna
Published: August 2024

This article examines the relationship between different types of institutional trust and online political activity. To assess online political activity, the authors developed an original methodology (questionnaire) "Online Political Activity Assessment Questionnaire", including two subscales “Political self-expression on the Internet” and “Online political activism”. Questions from the European Social Survey (ESS) questionnaire were used to assess institutional trust. The sample included 502 respondents (60% were women). The study found that online political expression was unrelated to the overall index of institutional trust, although a negative relationship was expected. At the same time, we found that institutional trust is positively associated with online political activism. That is, people who have higher institutional trust will more often vote via the Internet, participate in various Internet campaigns initiated by the state or structures (for example, volunteer) that are supported by the state. We come to the important conclusion that support for the state’s digital initiatives and willingness to use them in everyday life is largely associated with people’s institutional trust.
De los derechos de las mujeres al feminismo constitucional
Authors: Santos-Rodríguez Patricia
Published: August 2024

El estudio trata de responder a la pregunta sobre la pertinencia de incluir explícitamente los derechos de las mujeres en las constituciones contemporáneas. Ofrece una aproximación historiográfica a estos primeros derechos, como parte esencial del principio de igualdad, hasta su actual reivindicación de ser incorporados a los textos jurídicos fundamentales. Se describe la transformación del contenido de dichos derechos por influencia de los movimientos feministas, y se analiza el nuevo feminismo constitucional, en sus raíces antropológicas y consecuencias jurídicas.
¿Quién decide?
Authors: Íñiguez Manso Andrea
Published: August 2024

El objetivo de este artículo es llevar a cabo un análisis del fallo de la Corte Suprema de los Estados Unidos, causa rol 595 US (2022), que dejó sin efecto el mandato de vacunación dictada por la OSHA.A partir de lo resuelto por la Corte Suprema de Estados Unidos se pueden profundizar dos temas que tienen importancia para la doctrina judicial. Por una parte, el principio de no delegación y separación de los poderes del Estado y, por otra, la relación que existe entre la ley que crea una agencia de gobierno y los decretos dictados por esas mismas agencias.
¿Cuál es la naturaleza jurídica de las criptomonedas en Chile?
Authors: Cuevas Contreras Alfonso Jacob
Published: August 2024

A través de este trabajo se responde a la pregunta: ¿cuál es la naturaleza jurídica de las criptomonedas en Chile? Por lo que se analiza brevemente algunas legislaciones comparadas, además de brindar las nociones básicas de su conceptualización y la tecnología empleada.
Reflexiones sobre el Banco Central de Chile en el rechazado borrador constitucional del año 2022
Authors: Lagos Torres Alejandro
Published: August 2024

Analizamos el diseño institucional del Banco Central de Chile en el borrador de nueva Constitución rechazado por el pueblo de Chile el 4 de septiembre de 2022. Para ello, proponemos una perspectiva jurídica además de una consideración respecto del buen desempeño del banco durante los últimos treinta años y el conocimiento científicamente afianzado en política monetaria, tratando de imaginar qué habría sucedido en caso de haberse aprobado el borrador de nueva Constitución.
"Familia, raza y Nación en tiempos de posfascismo"
Authors: Segovia Juan Fernando
Published: August 2024

Fundación de los Comunes (ed.), Familia, raza y nación en tiempos de posfascismo, Madrid, Traficantes de Sueños, 2020.
"De la ultraizquierda a la teoría de la cominización"
Authors: Segovia Juan Fernando
Published: August 2024

Théorie Communiste, De la ultraizquierda a la teoría de la comunización, traducción y prólogo de Federico Corriente, Rosario, Lazo Negro, 2022.
Derecho disciplinario e infidelidad matrimonial
Authors: Román Cordero Cristian
Published: August 2024

En este trabajo comentaremos la sentencia de la Corte Suprema rol n.º 17.750-2019 que acogió (con cuatro votos a favor y uno en contra) el recurso de protección deducido por un teniente 2.º de la Armada, soltero, en contra de un decreto de la Subsecretaría para las FFAA que lo sancionó con retiro absoluto por haber mantenido una relación sentimental con la cónyuge de otro miembro de esa institución castrense.
Thực trạng quản lý xây dựng văn hoá nhà trường ở các trường tiểu học thành phố Sa Đéc, tỉnh Đồng Tháp
Authors: Nguyễn Hoàng Minh Đức , Huỳnh Mộng Tuyền
Published: August 2024

Văn hóa là nền tảng, mục tiêu, động lực cho sự phát triển, khẳng định thương hiệu của nhà trường. Qua sử dụng phối hợp các phương pháp điều tra thu thập số liệu, thông tin bằng các phiếu hỏi, phỏng vấn, quan sát, kết quả nghiên cứu đạt được là khung lý luận và thực trạng quản lý xây dựng văn hoá nhà trường ở các trường tiểu học thành phố Sa Đéc, tỉnh Đồng Tháp. Lý luận khoa học và thực trạng quản lý xây dựng văn hoá nhà trường được tập trung nghiên cứu theo 4 công việc chính lập kế hoạch, tổ chức chỉ đạo, kiểm tra, đánh. Lý luận và thực trạng nghiên cứu toàn diện, trọng tâm, sát thực, được đánh giá và rút ra được những kết luận cụ thể. Những luận cứ lí luận và thực tiễn nghiên cứu làm cơ sở vững chắc cho đề xuất biện pháp quản lý xây dựng văn hoá nhà trường ở trường tiểu học thành phố Sa Đéc, tỉnh Đồng Tháp.
A New Family of Power Function- Lindley Distribution
Authors: Muhi Emad Farhood
Published: August 2024

As data types evolved many problems related to the representation and modeling of this data began to emerge creating a need to find solutions. Over the past few years many methods have been proposed to generate new families of continuous distributions and study them in various applications including medicine engineering physics economics finance biology and environmental studies and the solution is to extend these distributions.    In recent years many methods have been proposed to create new distributions. We generate  a new of family distributions named PF- LD . Some properties of our distribution are introduced. Such as rth moment function, reliability function, hazard rate function, Shannon entropy function and stress-strength models. A simulation study was carried out for this compare the performance of different estimates from PF-LD. We create random variable from PF-LD for different sample sizes and different parameters values. The simulation study was repeated every (1000N) with a sample sizes (n=30,60,160). And numerical simulations can be performed for different parameter values by solving nonlinear equations and calculating MSE for parameter estimation. The results we obtained using the Matlab code observed a lower MSE when the default parameter values were small. (β=0.5, λ=0.5, α =0.5  ). for all sample size . Based on the knowledge and information obtained from this research, we recommend, applying the proposed distribution to real data.
Crossing Intuitionistic KUS-Ideals on KUS-Algebras as an Extension of Bipolar Fuzzy Sets
Authors: Hasan Elaf R.
Published: August 2024

The concept crossing  intuitionistic structures  set is combination of intuitionistic fuzzy set and ℵfunction.In this paper,the concept  crossing intuitionistic ideals are introduced and several properties are investigated .Also,the relations between crossing intuitionistic KUSideals and crossing intuitionistic ideals are given .The image and the preimage of crossing intuitionistic KUS ideals under homomorphism of KUS algebras are defined and how the image and the preimage of crossing intuitionistic KUSideals under homomorphism of KUS algebras become crossing intuitionistic KUS ideals are studied.
Comparative assessment of bone cement implantation syndrome in cemented bipolar hemiarthroplasty: impact in patients with and without preexisting heart disease
Authors: Yuenyongviwat Varah , Janejaturanon Jiranuwat , Hongnaparak Theerawit , Iamthanaporn Khanin
Published: August 2024

Background

With the increasing incidence of hip fractures in older adults, hip replacement with a cemented femoral stem has become a viable treatment option. However, concerns regarding potential complications, particularly bone cement implantation syndrome (BCIS), especially in patients with preexisting medical conditions, have prompted orthopedic surgeons to explore alternative approaches.

Objective

The research question of this retrospective study is whether BCIS incidence in patients with preexisting heart disease undergoing cemented bipolar hemiarthroplasty is higher than that of patients without preexisting heart disease.

Methods

We retrospectively analyzed data from 311 patients undergoing cemented bipolar hemiarthroplasty, including 188 without preexisting heart disease and 123 with heart disease. Anesthetic records were reviewed to assess parameters related to BCIS. BCIS severity was graded systematically, emphasizing key metrics, such as hypotension, arterial desaturation, and the loss of consciousness.

Results

Among the patients, no perioperative deaths occurred. Grade 1 BCIS was observed in 13 patients (4.18 %), without instances of grade 2 or 3. Notably, grade 1 BCIS was observed in only 2 patients with preexisting heart disease (1.63%) and 11 patients (5.85%) without preexisting heart disease.

Conclusion

BCIS incidence after cemented bipolar hemiarthroplasty was minimal, with a predominantly low severity. Importantly, preexisting heart disease did not pose a significant increase in the risk of BCIS. This finding confirms the safety of cemented bipolar hemiarthroplasty in older adults.

Level of Evidence

III
Anesthetic Management of a Patient with Renal Cell Carcinoma-Associated Venous Thrombosis and Massive Transfusion
Authors: Zhang Gary , Palacios Ryan , Hasoon Jamal , Robinson Christopher L , Nguyen Anvinh
Published: August 2024

A 53-year-old male with a history of multiple deep venous thromboses (DVTs) underwent a right open radical nephrectomy with inferior vena cava (IVC) thrombectomy in the context of renal cell carcinoma (RCC)-associated venous thrombosis. Imaging and renal biopsy revealed a diagnosis of RCC with non-occlusive thrombosis of the left renal vein and occlusive thrombosis of the infrarenal IVC. The major risks of concern for the procedure included thrombus embolization from surgical manipulation and massive bleeding. Intraoperatively, the patient experienced significant hemorrhage requiring massive transfusion protocol. The purpose of this case report is to emphasize the importance of multidisciplinary involvement, intraoperative thrombus monitoring, and principles of massive transfusion in the management of similar cases.
Pengaruh Servicescape Dan Kualitas Pelayanan Terhadap Customer Emotion Melalui Kepuasan Konsumen
Authors: Anggraini Sesilia , Iskandar Donant Alananto
Published: August 2024

This study aims to determine how much influence servicescape and service quality on customer emotion through customer satisfaction at the coffee square. This research is a quantitative approach using the SPSS Statistics 20 program with a total sample of 185 respondents whose people live in Jadebek who have eaten or drank at Alun Alun Coffee by using nonprobability sampling and purposive sampling techniques. The results of this research t test shows that servicescape directly affects customer emotion with a significance value of 0.001 <0.05 and a t value of 3.463> 1.973 so that servicescape is very important for Alun-Alun Coffee. Service quality variables have a direct effect on customer emotion with a significance value of 0.000> 0.05 and a t value of 10.745> 1.973 which means that partially service quality variables have a positive effect on customer emotion at Alun Alun Coffee. Meanwhile, servicescape directly affects customer emotion through customer satisfaction with a significance value of 0.000> 0.05 and a t value of 4.598> 1.973. The benefit of this research for Alun Alun Coffee is as input or evaluation in order to maintain and improve facilities and service quality to compete with other competitors.
Analisis Pembelajaran Elektronik Dan Pola Pikir Tumbuh Kembang Pada Ketangkasan Karyawan Serta Dosen STIE PBM
Authors: Effendy Nazory
Published: August 2024

This study aims to determine the effect of e-learning and growth mindset to workforce agility at Insurance Company XYZ. This study using qualitative approach as well as observation and interview to collect data and information about the problems that might be happen. This study conducted interviews with 5 persons who are the employees of Insurance Company XYZ.In this study it was found that there were various positive and negative impacts. Even tho, the results of this study show that e-learning and growth mindset have an effect on workforce agility at Insurance Company XYZ. Therefore, the researcher give the suggestion for Insurance Company XYZ is to always empower, motivate and provide moral support for the employees to be able to provide the best for the company and not give up easily at work.
El principio de solidaridad familiar a la luz de la jurisprudencia de la Corte Constitucional colombiana
Authors: Alarcón Palacio Yadira Elena
Published: August 2024

Se pretende mostrar el desarrollo del principio de solidaridad a partir de los postuladosconstitucionales y de la jurisprudencia de la Corte Constitucional colombiana, paraestablecer cómo se ha interpretado su aplicación en el ámbito familiar, cuáles seríanlos rasgos característicos de su alcance y quiénes son los sujetos jurídicos que, porvirtud de tal principio, adquieren unas obligaciones y detentan unos derechos predicables,en primer lugar, de sus parientes y, a falta de ellos, de la sociedad y del Estado.
Blastic plasmacytoid dendritic cell neoplasm: Two case reports
Authors: Ma Yi-Qian , Sun Zhan , Li Yu-Mei , Xu Hui
Published: August 2024

BACKGROUND

Blastic plasmacytoid dendritic cell tumor (BPDCN) is a rare and highly invasive lymphohematopoietic tumor that originates from plasmacytoid dendritic cells. BPDCN has an extremely poor prognosis. Skin lesions are usually the first manifestation of BPDCN, although the tumor may also invade the bone marrow, lymph nodes, peripheral blood, and other parts of the body, leading to several other manifestations, requiring further differentiation through skin biopsy and immunohistochemistry.

CASE SUMMARY

In the present paper, the cases of 2 patients diagnosed with BPDCN are discussed. The immunohistochemistry analysis of these 2 patients revealed positivity for CD4, CD56, and CD123. Currently, no standard chemotherapy regimen is available for BPDCN. Therefore, intensive therapy for acute lymphoblastic leukemia was applied as the treatment method for these 2 cases.

CONCLUSION

Although allogeneic bone marrow transplantation could be further effective in prolonging the median survival the ultimate prognosis was unfavorable. Future treatment modalities tailored for elderly patients will help prolong survival.
Fatty acid composition of anchovetas at different life stages and geographic zones
Authors: Klarian Sebastian A , Cárcamo Carolina , Leiva Francisco , Valdes Juan Antonio , Pizarro Nancy , Fernandoy Francisco
Published: August 2024

Fatty acids are crucial for energy transfer within food webs, acting as biomarkers due to their persistence across trophic levels. The anchoveta is economically and ecologically important, with extensive research on its biology. However, the impact of diet on its fatty acid composition
across different regions and sizes is less understood. Fatty acids were extracted, saponified, and prepared as fatty acid methyl esters for analysis on a gas chromatograph. This study reveals that anchoveta have high levels of saturated fatty acids (SAFAs) and primarily use docosahexaenoic
acid (DHA) as their energy source. We also found that the fatty acid profile of anchoveta changes throughout their ontogeny, with prerecruits having lower DHA levels compared to adults. Interestingly, anchoveta from similar geographic regions like Chile, Peru, and South Africa share similar
fatty acid profiles. This suggests a potential link to shared upwelling habitats that are rich in nutrients. Furthermore, our study challenges the traditional assumption that phytoplankton is the main food source for anchoveta. The results highlight the need for further research to pinpoint
their primary energy source.