bluuebunny/crossref_metadata_2025 huggingface dataset:
KADINLARI CEZALANDIRAN KADIN: AZİZ JERONIMOLU MAGDALENA
Authors: Kalkan Mehmet Talha
Published: June 2024

XVI. yüzyılın başından itibaren yoksulluğa ve cinselliğe yönelik bakış açısının değişmeye başlaması neticesinde hem yoksulluk hem de cinsellik kontrol edilmesi, denetlenmesi ve çözülmesi gereken meseleler olarak görülmüştür. Nitekim XVI. yüzyılın sonlarında toplumsal, iktisadi, dinî, politik ve ekonomik sorunlar ile boğuşmaya başlayan İspanya’da da benzer bir durum yaşanmış ve hayat kadınlarına yönelik denetimler ve kısıtlamalar artmıştır. Daha önceleri hoş karşılanan bir grup olmasa da işlerini yapmalarına izin verilen hayat kadınları, İspanyol düşünürler ve yazarlar tarafından toplumu hem ahlaki hem de sıhhi açıdan kirletmekle suçlanmışlardır. Bu nedenle, kilise ve devlet tarafından kontrol altına alınmak istenen bu grup, yalnızca hayat kadınları ile sınırlı kalmayıp avare, başıboş, büyücü, dilenci, tembel ve hırsız kadınlar gibi farklı kadınları da kapsamıştır. Bahsi geçen kadınları galera adı verilen binalara hapsederek onları rehabilite etmeyi amaçlayan Aziz Jeronimolu Magdalena da kaleme almış olduğu Razón y forma de la Galera y Casa Real adlı eserini Kral III. Felipe’ye sunmuş ve İspanyol toplumunun bozulmasına neden olan kadınların tutuklanmasıyla toplumun arınabileceğini ifade etmiştir. İşbu çalışma da Aziz Jeronimolu Magdalena tarafından ortaya atılmış olan galera adlı kurumun ortaya çıkma nedenleri ile olası sonuçlarını ele almış, onun rehabilitasyon ve disiplin ile ilişkisi üzerinde durmuştur.
KARADENİZ’E YÖNELİK RUS GENİŞLEMESİ VE COĞRAFİ HARİTACILIĞININ ETKİSİ: CORNELİUS CRUYS’UN 1699 YILINDA HAZIRLADIĞI “DON NEHRİ ATLASI” ÇERÇEVESİNDE BİR DEĞERLENDİRME
Authors: Bayındır Cem
Published: June 2024

XVII. yüzyıl sonlarında Rusya'nın güneye doğru genişlemesi, Osmanlı Devleti ile olan stratejik rekabetini şekillendirmiş ve iki devlet arasındaki ilişkilerde yeni bir dönemin başlangıcını işaret etmiştir. Bu dönemde, Rusya’nın Karadeniz’e yönelik genişleme politikaları, Osmanlı Devleti topraklarının haritalandırılmasının önemini artırmıştır. Bu haritalar, Rusya’nın bölgesel etki alanını genişletmek ve sınır bölgelerindeki askeri planlamalarını güçlendirmek amacıyla kullanılmaktaydı. Özellikle I. Petro döneminden itibaren Rusya’nın, Karadeniz hedefleri doğrultusunda bölgenin haritalandırılmasına duyulan ihtiyaç artmış ve haritacılık hızla gelişim göstermiştir. Bu ihtiyaç doğrultusunda, Hollanda’daki tersanelerden Rus hizmetine alınan Cornelius Cruys tarafından 1699 yılında “Don Nehri Atlası” hazırlanmıştır. Bu atlas, Rusya'nın denizcilik ve haritacılık kapasitesini nasıl geliştirdiğini ve Osmanlı sınırları içinde stratejik noktalara olan erişimini nasıl artırdığını göstermesi açısından önemlidir. Ayrıca bu atlas, Don Nehri havzasının siyasi, sosyal ve kültürel yapısına dair tarihsel bilgiler de sunması açısından da önem taşımaktadır. Bu makalede, haritacılığın askeri ve stratejik planlamalar üzerinde etkilerini vurgulamakla birlikte Rusya’nın Karadeniz’e doğru genişleme politikalarının daha iyi anlaşılmasına katkıda bulunulması hedeflenmektedir.
KENTSEL DOKULARDA TARİHİ MEZARLIK ALANLARININ VE MEZAR TAŞLARININ DURUMLARI (Tokat ve Rize Örnekleriyle)
Authors: Hanoğlu Canan
Published: June 2024

Türk-İslam dünyasında önemli bir yeri olan mezarlıklar, insanlar tarafından değer verilen, saygı duyulan alanlardır. Özellikle Osmanlı kent dokusu içerisinde mezarlıklara, hazirelere, mezar taşlarına ve türbelere oldukça önem verilmiş ve mezarlıklar adeta birer cennet bahçesine dönüştürülmüştür. Bu durum yabancı seyyahların da dikkatini çekmiş; hatıralarına, gravürlerine konu olmuştur. O dönemde mezarlıklar İstanbul başta olmak üzere şehirlerin tarihi dokusunun oluşmasında etkili unsurlardan biriyken kentleşmeyle birlikte bu etki giderek azalmıştır.
Kentleşmenin getirmiş olduğu bir takım faaliyetler tarihi eserlerin zarar görmesine hatta yok olmasına sebep olabilmektedir. Eski mezarlık ve hazire alanları bu durumdan en çok etkilenen yerlerin başında gelmektedir. Şehirleşme ve modernleşme çalışmaları kapsamında yapılan çeşitli imar faaliyetleri, yanı sıra artan nüfus, definecilerin yapmış olduğu katliamlar, insan ve doğa tahribatı mezarlık alanlarının ve bu alanlarda bulunan mezar taşlarının her geçen gün, sayılarının azalmasına ve yok olup gitmesine neden olmaktadır.
Tokat ve Rize illeri özelinde hazırlanan bu çalışmada, kentleşmeye yönelik çalışmalar, bilinçli-bilinçsiz yapılan bir takım uygulamalarla tarihi mezarlık alanlarının ve mezar taşlarının durumlarını göstermek amaçlanmıştır. Tokat ve Rize mezar taşları ile ilgili yapmış olduğumuz araştırmalar sırasında karşılaştığımız bazı tarihî mezarlık alanları, hazireler ve mezar taşlarından örnekler verilerek önceki ve mevcut durumları ile ilgili gözlemlediğimiz tespitler paylaşılmıştır.
Estrategias psicopedagógicas sustentadas en ludoterapia para el fortalecimiento de funciones básicas en niños
Authors: Casanova Naranjo Stephanie Gissela , Taro Joseph
Published: June 2024

La presente investigación aborda las estrategias psicopedagógicas sustentadas en la ludoterapia. Estas estrategias se ponen de manifiesto en actividades que permiten al estudiante adquirir el aprendizaje y en el caso de los más pequeños fortalecer las funciones básicas que son indispensables para el proceso de la lectoescritura. Para ello se planteó como objetivo: proponer estrategias psicopedagógicas sustentadas en la ludoterapia para fortalecer las funciones básicas en niños de Inicial II. La investigación se realizó bajo un enfoque cuantitativo con un alcance exploratorio y descriptivo. Para la recolección de datos se aplicó la prueba de funciones básicas de Dr. Ivan Espinoza a 31 niños inscritos en Inicial II además de la aplicación de una encuesta a docentes que midió tres dimensiones: cognitiva, procedimental y actitudinal. En el análisis de resultados se logró identificar las principales insuficiencias en áreas evaluadas en los niños objeto de estudio. Estas insuficiencias evidenciaron la falta de capacitación constante de docentes en estrategias psicopedagógicas sustentadas en ludoterapia. Desde el aporte práctica, la investigación permitió proponer estrategias psicopedagógocas sustentadas en ludoterapia para ser aplicadas por los docentes en el proceso de enseñanza aprendizaje con el apoyo de padres de familia.
(Des) Control Social: El Fantasma de la Política
Authors: De la Fuente Vera Ana Perla , Hernández Landaverde Jessica Paloma , Martínez Gómez Jesús Armando
Published: June 2024

Este ensayo se presenta como resultado de una investigación exploratoria, desarrollada con base en el método de análisis de documentos y un enfoque crítico, con el objetivo de valorar la incidencia y alcance de las neurociencias y las tecnologías emergentes-sobre todo la IA y redes sociales- en el control social criminológico y el neuromarketing, y las consecuencias de su mal uso en la población, con especial referencia a la juventud como grupo etario vulnerable, presa muchas veces del control social ejercido por fuerzas políticas y grupos de poder a través de las plataformas digitales. Se comienza analizando el surgimiento y desarrollo de las neurociencias, para posteriormente valorar su relación con las ciencias sociales, lo que permite determinar su verdadero alcance y cómo se utilizan sus aportaciones en internet y en particular en las redes sociales con fines de control social, por parte de la criminología, pero también de fuerzas políticas que, con afán de buscar seguidores para las campañas electorales, transforman muchas veces el control social en descontrol. La investigación realizada nos lleva a concluir que lejos de empoderar a la población, y en particular a la juventud, para que defiendan sus derechos y favorecer la prevención social, el uso de neuromarketing conduce generalmente a la instrumentalización de las personas, en particular de las más jóvenes.
Analysis of Regional Tax Management Based On Information System Management of Regional Original Revenue (SIP-PAD) at The Agency Kendari City Regional Revenue (BAPENDA)
Authors: Basru Wawo Andi , Rahmadini Tasya , Nur Muh. , Prasetyo Arjuna Bucek Jalu
Published: June 2024

This research aims to find out and analyze how regional tax management is based on the Regional Original Income Management Information System (SIP-PAD) at the Kendari City Regional Revenue Agency and the extent to which regional tax management is based on the Regional Original Income Management Information System (SIP-PAD) at the Revenue Agency Kendari City area. This research uses qualitative methods with the data used coming from primary data in the form of interviews and secondary data in the form of documentation. The results of this research show that SIP-PAD based Regional Tax Management at BAPENDA Kendari City has been implemented in accordance with existing policies, namely PP No. 35 Article 59 of 2023 where Regional Governments are required to make Payments and Deposits via an electronic-based system. Which refers to the previous statement, namely Minister of Home Affairs Regulation Number 56 of 2021 concerning Teams for the Acceleration and Expansion of Digitalization in Provincial and Regency/City Regions as well as procedures for Implementing Regional Government Transaction Etronification (E-STPD). This is because the integrated and computerized system allows tighter monitoring of potential tax fraud and abuse.
INFRAESTRUTURA EM NUVEM: ASPECTOS RELEVANTES PARA ANÁLISE EM UM PROCESSO DE MIGRAÇÃO
Authors: DOS SANTOS FABRICIO COSTA , DOS SANTOS CLAYTON EDUARDO
Published: June 2024

O trabalho analisa as principais ferramentas de TI disponíveis nos modelos de computação em nuvem e ambiente corporativo tradicional (on-premise). O objetivo é comparar seus diferenciais, funcionalidades e aplicabilidades. A computação em nuvem revolucionou o uso da tecnologia pelas organizações ao oferecer recursos sob demanda, de forma escalável e econômica. Já as ferramentas internas desempenharam papel estratégico ao otimizar ambientes corporativos. O estudo mapeia a evolução histórica dos dois modelos, desde os primórdios da virtualização até tendências atuais como computação em edge, híbrida e serviços especializados. A análise qualitativa, por meio de revisão bibliográfica, permitiu identificar benefícios, limitações e casos de uso mais adequados para cada abordagem. Conclui-se que a melhor estratégia envolve combinar soluções internas e externas, migrando aplicações para a nuvem conforme a maturidade tecnológica e necessidades do negócio. Os resultados auxiliam gestores de TI na escolha da abordagem mais alinhada aos seus objetivos..
Changes in symptom burden and quality of life among women with uterine fibroids receiving relugolix combination therapy: a plain language summary
Authors: Stewart Elizabeth A , Lukes Andrea S , Venturella Roberta , Li Yulan , Hunsche Elke , Wagman Rachel B , Al-Hendy Ayman
Published: June 2024

What is this summary about?

This is a summary of findings from two research studies (known as clinical trials). The studies looked at how well a medicine called relugolix combination therapy worked in women with heavy menstrual bleeding (heavy bleeding during a period) with uterine fibroids (noncancerous or benign growths in the uterus). In this analysis of the studies, researchers looked at how patients self-reported their uterine fibroid symptoms before and after taking relugolix combination therapy. Researchers also looked at how patients self-reported the impact of uterine fibroids on their health-related quality of life before and after taking relugolix combination therapy.

What were the results?

Women took either relugolix combination therapy or placebo (a pill that contains no medicine) by mouth once daily for 24 weeks. Women completed the Uterine Fibroid Symptom and Quality of Life questionnaire (where “quality of life” refers to the women's health-related quality of life related to uterine fibroids) before, during, and after treatment. The questionnaire let researchers see if the women felt that relugolix combination therapy decreased the burden of uterine fibroid symptoms and improved the women's health-related quality of life related to uterine fibroids. More women said that they felt less distress due to their uterine fibroid symptoms and that their health-related quality of life related to uterine fibroids was better after taking relugolix combination therapy compared with women who took placebo.

What do the results mean?

Relugolix combination therapy may lessen distress associated with uterine fibroid symptoms and improve health-related quality of life related to uterine fibroids.
EU FDI Screening – Level Up in Multilevel Governance?
Authors: Crivoi Alexia
Published: June 2024

The current Union framework for the screening of foreign direct investment is about to be renewed. In January 2024, the Commission presented a proposal for a new Regulation that is supposed to bring about more convergence in the currently strongly fragmented national legislation landscape. The Proposal obliges Member States to introduce national screening mechanisms and tries to harmonise those by prescribing a minimum scope of application and a number of screening factors. The article gives an overview of the changes and tries to analyse in how far they can contribute to a more enhanced, effective screening exercise across the Union. In addition, the Proposal raises questions as to its conformity with primary law, in particular with regard to its appropriate legal basis and its relation to the free movement rules. By expanding FDI screening also to certain types of foreign-held intra-EU investment, a dichotomy between FDI screening and the freedom of establishment is created. The article thus tries to analyse how the Proposal can be reconciliated with the European Court of Justice’s (strict) case law on restrictions to the freedom of establishment.
Rancangan Geometri lereng Penambangan Bijih Nikel laterit pada blok ulusawa 10 pt gerbang multi sejahtera kecamatan laonti kabupaten konawe selatan provinsi sulawesi tenggara
Authors: Hakim Hardiyanti , Anshari Erwin , Mili Marwan Zam
Published: June 2024

Nilai faktor keamanan lereng tambang di Indonesia diatur dalam Keputusan Menteri ESDM No. 1827 K/30/MEM Tahun 2018 tetang Pedoman Pelakasanaan Kaidah Teknik Pertambangan yang Baik. Penelitian ini bertujuan untuk memberikan rekomendasi geometri lereng penambangan yang stabil dan optimal berdasarkan sifat fisik dan sifat mekanik tanah penyusun lereng pada rencana penambangan Blok Ulusawa 10 PT. Gerbang Multi Sejahtera. Metode yang digunakan dalam penentuan kestabilan lereng pada penelitian ini adalah metode Bishop Simplified. Hasil penelitian menunjukkan simulasi kestabilan lereng pada profil endapan nikel laterit dalam kondisi terdistribusi beban tambahan oleh alat gali-muat Excavator Sumitomo SH350 HD-6 sebesar 56 kN/m2 dan beban dari alat angkut Dumptruck Mercedes Benz Axor 2528C (6x4) sebesar 13,30 kN/m2 serta pengaruh getaran gempa sebesar 0,4 gal (Aulia et al., 2019). Untuk lereng tunggal setinggi 5 meter lapisan Saprolite pada kondisi dinamis dengan sudut 45o dan lebar Bench 2 meter adalah material yang memiliki nilai FK paling rendah, yaitu FK = 1,590 dengan PL = 3,10% sehingga dapat mewakili semua material sebagai kondisi paling pesimis dan digunakan sebagai acuan untuk merancang geometri lereng keseluruhan dengan tinggi maksimum 65 meter. Berdasarkan hasil penelitian dapat disimpulkan untuk rekomendasi geometri lereng penambangan menggunakan geometri lereng keseluruhan dengan tinggi maksimum 65 meter, lebar bench 2 meter, lebar ramp 9 meter dengan FK dalam kondisi dinamis sebesar 1,226 dan PL = 17,70% serta sudut kemiringan lereng keseluruhan 27o dengan nilai FK dalam keadaan terdistribusi beban (dinamis) = 1,203 dan PL = 13,10% .
The Principles of Classical Education
Authors: Diener David ,   Philosophy Documentation Center
Published: June 2024

The contemporary classical education movement has grown rapidly and is comprised of a wide variety of private schools, homeschoolers, public charter schools, policy makers, higher education programs, professional associations, journals, trade publications, and think tanks. What is it that unites this thick network of disparate individuals and organizations into a cohesive movement? This article attempts to answer that question by explaining ten principles that have characterized the tradition of classical education throughout history across millennia, continents, languages, and cultures. While not exhaustive, these ten principles represent central tenants of the long tradition of classical education and the contemporary classical education movement. The principles are thus a philosophically and historically grounded means by which to differentiate classical education from other educational paradigms and also provide a common understanding of classical education around which various constituencies within the contemporary movement can coalesce.
SURVEY OF ELEVATED BLOOD PRESSURE IN CHILDREN
Authors: Nguyen Minh Phuong , Nguyen Quoc Thinh , Truong Ngoc Phuoc , Nguyen Van Trinh , Trinh Phuong Tram , Nguyen Nhat Duy , Lu Tri Dien , Vo Van Thi , Le Van Minh
Published: June 2024

Background: Hypertension is one of the leading risk factors for death, one of the main risks of cardiovascular disease. Clinical characteristics of hypertension are diverse, the early detection of symptoms of hypertension contributes significantly to early diagnosis and treatment. In Can Tho, there is little research on hypertension in children. Objectives: Describe the clinical and subclinical characteristics of hypertensive children being treated at the Cardiology Department, Can Tho Children’s Hospital. Materials and methods: Analytical descriptive cross-sectional study on 96 pediatric patients diagnosed with hypertension at Can Tho Pediatrics Hospital. Research subjects: Pediatric patients (<16 years old) being treated at the department who are expected to have hypertension over a period of time. Sample selection criteria: Pediatric patients are expected to have hypertension determined according to the standards of the new Guidelines in Clinical Practice of the American Academy of Pediatrics (AAP) 2017. Exclusion criteria: Family members do not agree to allow the patient to participate in the study. Children are not appropriate for measuring BP due tocongenital anomalies: Ventricular septal defect, Atrial septal defect, Patent ductus arteriosus, Tetralogy of Fallot. Results: The common age group is under 13 years old (60.4%). The male and female gender ratio is approximately 2.1/1. The stage 2 hypertension classification is the most common (49.8%). The rate of neurological, gastrointestinal and cardiovascular symptoms was 59.4%, respectively; 19.8%; 24%. And there is no association between gastrointestinal, cardiovascular clinical symptoms and the grade of hypertension (p>0.05). Hyperlipidemia, HbA1C in children with hypertension accounted for a high rate of 47.1% and 50%. While in BUN disorder, proteinuria accounted for a low rate of 5.3% and 26.3%. No abnormalities were noted on renal Doppler ultrasound. The rate of abnormal results on echocardiography, chest X-ray and ECG was 53.3%; 23.3%;13.7% respectively.
INITIATION OF PROCESS STANDARDIZATION TO FABRICATE DEMINERALIZED BONE DIRECTED TOWARDS MAKING MATERIALS FOR BONE GRAFTING
Authors: Le Chi Linh , Huynh Duy Thao , Nguyen Van Doi , Trinh Ngoc Khoa , Ha Thi Thao Mai
Published: June 2024

Background: Bone tissue, a vital component for self-healing. This inherent regenerative capacity enables bones to repair themselves following injury or damage. Understanding the mechanisms behind bone tissue self-healing is of great significance in the field of medical research and has implications for the development of novel therapeutic approaches. In this article, we explore the fundamental characteristics and mechanisms underlying the self-healing properties of bone tissue. In certain instances of trauma or pathological conditions resulting in bone defects, the natural healing process may be insufficient. Consequently, the implementation of bone transplant interventions becomes imperative for successful bone regeneration. The predominant origins of bone grafts encompass autologous, homologous, and heterologous sources. The allograft, a widely utilized bone grafting technique, has gained significant popularity, and is currently in high demand within the medical field. The current state of allograft utilization in our nation has proven insufficient in meeting the demands of patients. Henceforth, a method has been devised and standardized for the procurement of demineralized osseous tissue, a crucial investigation in light of the insufficiency of allografts in meeting the requirements of patients. Objectives: Initially, standardizing an efficient procedure to obtain demineralized bone sources from human skull fragments from three different inclusion methods. Materials and Methods: Using three different types of solutions to obtain demineralized bone from human skull tissue including solutions of Formic Acid (10%), Hydrochloric Acid (5%), a mixture of solution: Formic Acid (10%) - Acid Hydrochloric (5%) (ratio 1:1,v/v). Demineralized bones were evaluated by comparing the mineral content extracted from bone samples, demineralization time, and analysis of ions concentration in bone samples (including Ca and P) before and after demineralization. Besides, demineralized bones were histologically stained before and after demineralization to assess the bone structure. Results: The Ca and P extraction rates of this method are high and standard, about 98% and 93%, respectively. The demineralization process only takes about five days. Relative bone tissue retains most of the structure of compact bone tissue. Conclusion: The procedure that our team has established is the right one for obtaining demineralized bone as bone replacement material and applies to a wide variety of human bone tissue.
RESEARCH ON CLINICAL CHARACTERISTICS AND TREATMENT RESULTS OF DERMATOPHYTOSIS PATIENTS WITH THE COMBINATION OF TOPICAL TERBINAFINE AND ORAL ITRACONAZOLE
Authors: Lac Thi Kim Ngan , Nguyen Hai Dang , Pham Thanh Thao , Tran Gia Hung
Published: June 2024

Background: Currently, many patients with dermatophytosis are treated with a variety of antifungal drugs but they are ineffective and relapses are common. Many antifungal drugs have been used but fails to treat the disease, which can globally become an issue in medical practice. The combination of antifungal drugs for the treatment of dermatophytosis, including oral itraconazole and topical terbinafine, has been shown to be more effective than monotherapy. However there has not been much research on the effectiveness of this combination treating dermatophytosis in Vietnam. Objectives: To describe the clinical characteristics and evaluate the results of patients with dermatophytosis treated with the combination of oral itraconazole and topical terbinafine at Can Tho Hospital of Dermato-Venereology in 2023. Materials and methods: a cross-sectional descriptive study was conducted on 53 patients who were diagnosed with dermatophytosis at Can Tho Hospital of Dermato-Venereology from May to November 2023. Results: the age group of 16 – 30 years old (47.2%) and male gender (67.9%) were the most common. The dominant clinical characteristics were pruritus (96.2%), erythema (100%), scaling (90.6%), central skin atrophy (88.7%), tinea corporis (90.6%), tinea cruris (28.3%), polycyclic pattern (79.2%) and round pattern (71.7%). The severity scores of the three symptoms and signs (pruritus, erythema and scaling) at the second week and fourth week were significantly decreased, compared with their baseline values (p<0.001). The cure rate of the patients after the second and fourth weeks of treatment were 28.3% and 90.6% respectively. Conclusion: pruritus, erythema, scaling, central skin atrophy, tinea corporis, tinea cruris, polycyclic pattern and round pattern were the most common clinical characteristics in dermatophytosis. With the treatment that combined of topical terbinafine and oral itraconazole, symptoms of the disease were significantly reduced
RESEARCH ON THE FORMULATION OF NANOPARTICLES CONTAINING MANGIFERIN USING SELF-ASSEMBLY METHOD
Authors: Huynh Thi My Duyen , Do Hoang Quyen , Pham Dinh Duy
Published: June 2024

Background: The use of natural-origin active compounds in disease treatment is currently a prevailing trend. Mangiferin, a major component found in mangoes, is present in relatively high proportions. However, mangiferin's disadvantages include low solubility and poor permeability. There are numerous methods available to improve solubility and permeability, among which selfassembly is noteworthy. Self-assembly involves the combination of certain molecules or macromolecules to form three-dimensional networks or other structures with new characteristics, phospholipids and chitosan are often used as raw materials for the self-assembly process to create nanoparticles. This method offers advantages such as high efficiency, simple implementation, short execution time, high retention efficiency, and increased permeability through biological membranes. Objectives: To develop a formulation and process for producing nano mangiferin using the selfassembly method with phosphatidylcholine and chitosan. Materials and methods: The solubility of mangiferin in high-proof ethanol was investigated, followed by an assessment of the influence of formulation factors and processes on the characteristics of nano-sized mangiferin particles. Results: The average solubility of mangiferin in 96% ethanol was approximately 0.5529±0.0003 mg/mL. The mole ratio of mangiferin to Lipoid S100 was 1:1, and the mass ratio of Lipoid S100 to chitosan was 20:1. A stirring speed of 1.000 revolutions per minute, reflux temperature of 70°C, reflux time of 2 hours. homogenization speed of 1,000 revolutions per minute, and homogenization time of 15 minutes produced the smallest nanoparticles (103.44±0.46 nm), with a low polydispersity index (0.281±0.009≤ 0.3) and zeta potential (31.95±0.08 mV ≥ +30 mV), encapsulation efficiency of 82.42±0.53%; loading capacity of 32.97±0.95%. Conclusions: A successful formulation of nanosized mangiferin particles was achieved using the self-assembly method, resulting in particles that meet the criteria of small size, uniformity, and durability. Moreover, nearly 100% mangiferin release was achieved after 60 minutes, indicating the promising potential for developing highly bioavailable oral formulations.
SALIVARY CHARACTERISTICS AMONG 12-YEAR-OLD CHILDREN WITH SIGNIFICANT CARIES INDEX FROM URBAN AND SUBURBAN SCHOOLS IN CAN THO CITY
Authors: Dang Vinh Quang , Dang Quang Vinh , Vo Quoc Toan , Nguyen Thu Uyen , Nguyen Huynh Thanh Thuy , Trinh Ngoc Thinh , Nguyen Thi Nhu Y , Nguyen Pham Truc Thanh , Nguyen Ngoc Nguyet Minh
Published: June 2024

Background: Dental caries is the most prevalent chronic childhood disease with numerous predisposing factors. Salivary properties have been linked to progressive dental caries in previous studies. However, the role of these contributing factors in the management of dental caries in children remains insufficient. Thus, the investigation of salivary characteristics from different types of communities within a specific pediatric population is an obvious demand. Objectives: To assess the salivary characteristics among school-going children aged 12 years from two urban and suburban schools in Can Tho city. Materials and methods: A cross-sectional descriptive study was conducted on 62 twelve-year-old students with significant caries index in two locations with different socioeconomic status in Can Tho city. Those participants underwent saliva testing by using a saliva testing kit (Saiva-Check BUFFER) to evaluate stimulated and unstimulated saliva parameters including consistency, flow rate, pH and buffering capacity. Results: Out of the total population, males and females made up 40.3% and 59.7%, respectively. Both boys and girls had similarities in all salivary parameters (p > 0.05). Nearly half of suburban students (48.4%) had resting frothy bubbly saliva while more than half of urban students (58.1%) had watery clear saliva at rest. All students had moderate and normal acidic saliva before and after stimulation regardless of living areas. The discrepancy in resting salivary viscosity, resting salivary pH was statistically significant based on region (p < 0.05). 64.5% of the students in both suburban and urban enclaves had a normal stimulated saliva flow rate. In contrast, a normal or high buffering capacity of stimulated saliva was only seen in a few students. Regarding the flow rate, pH, and buffering capacity of stimulated saliva, there were no differences between urban and suburban areas (p > 0.05). Conclusions: The findings of this study provide additional proof of the significance of salivary properties in assessing dental caries, especially in socioeconomic deprivation areas. Furthermore, it also implies that salivary parameters should be taken into account as a potential indicator for managing high caries-risk children.
EVIDENCE – BASED PRACTICE: ATTITUDES AND KNOWLEDGE AMONG UNDERGRADUATE NURSING AND MIDWIFERY STUDENTS AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY IN 2023 AND RELATED FACTORS
Authors: Mai Nguyen Thanh Truc , Ngo Thi Dung , Pham Le An , Nguyen Hong Thiep
Published: June 2024

Background: Evidence-based practice (EBP) is imperative for ensuring patient safety and enhancing the quality of education. In 2022, EBP was considered one of the compulsory standards for nursing and midwifery in Vietnam. The recognition of the attitude and knowledge in EBP is an essential step before applying evidence in clinical practice and teaching. Objectives: This study aimed to (1) describe the attitude and knowledge in EBP, and (2) identify the related factors which are associated with EBP attitude and knowledge. Materials and methods: A convenience sample with the cross – sectional descriptive design was conducted on 178 nursing and midwifery students (2nd - 4rd academic year) at the Faculty of Nursing and Medical Technology, Can Tho University of Medicine and Pharmacy from September to October - 2023. The subscale from the Evidence-based Practice Competence Questionnaire consisted of attitude and knowledge, developed by RuzafaMartinez in 2013 was used for this study. The Evidence-Based Competency Questionnaire is one of the most valid tools used in various studies by Ruzafa-Martinez. All questions were translated and reliability was measured. The reliability of the subscale (knowledge and attitude) was evaluated using Cronbach's alpha and internal consistency accounted for 0.88 and consisting of 8 and 9 questions, respectively. Results: Most of the nursing and midwifery students had a high attitude and knowledge in EBP. Genders, academic year, majors were identified as significant related factors for knowledge about applying evidence. Conclusions: Nursing and midwifery students at Can Tho University of Medicine and Pharmacy had a high level of skills and knowledge in EBP. Training institutions need to organize many classes and activities for EBP, and innovate teaching methods to train human resources to meet professional standards.
HEALTHCARE STUDENTS' READINESS OF INTERPROFESSIONAL LEARNING IN CAN THO UNIVERSITY OF MEDICINE AND PHARMACY: A CROSS-SECTIONAL STUDY
Authors: Nguyen Thi Kim Tuong , Nguyen Thanh Liem , Pham Thi Be Kieu , Nguyen Van Tuan
Published: June 2024

Background: The World Health Organization emphasizes the significance of interprofessional collaboration and education. Being aware of the value of collaboration among professionals within the healthcare team, the university in Vietnam has tended to prepare students for teamwork through interprofessional education. However, the success of interprofessional education is contingent upon the students' attitudes. Objectives: To identify students' attitudes at Can Tho University of Medicine and Pharmacy toward interprofessional learning and explore factors affecting their readiness for the program. Materials and methods: A cross-sectional study on 301 Can Tho University of Medicine and Pharmacy students in ten majors, responding to an online survey from May to July of 2023 using the Readiness for Interprofessional Learning Scale. Besides, we collected demographic information including age, gender, ethnicity, major, academic years, and info learned/experienced in the interprofessional education of students. Multivariate regression was used to explore factors affecting students' readiness for interprofessional learning. Results: Students replied to the questionnaire. All of them had no experience in interprofessional education (100%); almost all participants were Kinh ethnicity (91.7%), and female (72.8%). The average age was 19.9 ± 0.7 years old. Students studying in the 2nd year were 65.8%. Nursing students account for the highest proportion (21.3%). The total score on the 19item Readiness for Interprofessional Learning Scale rated by 301 students was 72.2 ± 8.2. The Positive professional identity subscale scored 4.1 ± 0.6 while the Teamwork and collaboration subscale scored 4.2 ± 0.5. The subscales measuring Negative professional identity and Roles and responsibilities had mean scores of 2.7 ± 1.1 and 3.4 ± 0.8, respectively. The study found an association between the subscale's score and the profession and ethnicity of students. Conclusion: Most students are ready for interprofessional learning, educators need to study how to build and introduce interprofessional education for them.
STUDY OF CLINICAL CHARACTERISTICS AND SOME RISK FACTORS OF MIGRAINE HEADACHE AT CAN THO CENTRAL GENERAL HOSPITAL IN 2022-2023
Authors: Ly Quoc Y , Dang Bich Loan , Duong Minh Thai , Pham To Tran , Le Van Minh
Published: June 2024

Background: Migraine is a common disorder; however, it is still not perfectly diagnosed and treated due to many difficulties in recognizing symptoms or accompanying risk factors. Understanding migraine headaches through surveying standard samples can guide clinicians in the appropriate way of diagnosis and treatment. Objectives: The study aimed to describe the clinical characteristics of migraine and to investigate some risk factors related to migraine headaches among patients examined at Can Tho Central General Hospital during 2022-2023. Materials and methods: A cross-sectional descriptive study was conducted on 46 patients diagnosed with migraine headaches at Can Tho Central General Hospital in 2022-2023. Results: We recorded that most of the patients experienced headaches lasting from 24 to 72 hours, unilateral (left or right side) fixed headaches, pulsatile headaches and severe intensity headaches with the proportions being 39.14%, 73.9%, 80.4%, and 63.1% respectively.  The symptoms accompanying the headache included nausea (67.4%), photophobia (52.2%), dizziness (34.8%), vomiting (32.6%), and absence of aura symptoms (unilateral fixed headache, nausea or/and vomiting, photophobia or/and phonophobia) accounting for 95.7%. Factors exacerbating headaches are stimulant use (21,7%), weather (19,6%), menstrual conditions aggravating headaches in 16.7% of female patients, and physical activity (13.0%). Factors alleviating headaches include using analgesics (60,9%), resting (39.1%), and avoiding exposure to light and photophobia (4.3%). Influencing factors include female (65.2%), insomnia (58.7%), anxiety disorder (52.2%), and family history of having a parent with migraine disease (4.3%). Conclusion: The highest rates were observed among patients experiencing unilateral (left or right side) fixed pain (73.9%) and pulsatile headache (80.4%). The most common accompanying symptom is nausea (67.4%). The proportion of migraineurs without aura symptoms accounts for 95.7%. Stimulant use (21.7%) is the factors that exacerbate headaches the most. On the other hand, avoiding exposure to light and noise reduces headaches in most cases (accounting for 60.9%).
CLINICAL AND SUBCLINICAL CHARACTERISTICS OF CARDIAC ARRHYTHMIAS IN CHILDREN AT CAN THO CHILDREN’S HOSPITAL
Authors: Pham Cao Tien Dung , Le Nguyen Hue Tran , Phan Minh Nhut , Luu Hong Hanh , Thai Tran Trung Thien , Nguyen Minh Phuong , Le Van Minh , Lu Tri Dien , Truong Ngoc Phuoc , Vo Van Thi
Published: June 2024

Introduction: Cardiac arrhythmia is a common cardiovascular emergency with diverse clinical and paraclinical characteristics. Arrhythmias can be harmless, asymptomatic, or have mild symptoms. However, some arrhythmias can cause discomfort with aggressive clinical and paraclinical manifestations, sometimes threatening the patient's life. This disease has very different clinical and paraclinical symptoms between types of arrhythmia. Objectives: Describe the clinical and paraclinical characteristics of arrhythmias in children at the Cardiovascular Department of Can Tho Children's Hospital. Subjects and Methods: A case series study was conducted on 45 children with arrhythmias at the Cardiovascular Department of Can Tho Children's Hospital, with consent obtained from their parents or caregivers to provide accurate information. All children 0 - 15 years old were diagnosed with arrhythmia based on ECG criteria or other investigation methods at the time of first examination or discovered during research at the Department of Cardiology in Can Tho Children's Hospital, whose parents or caregivers agree to provide accurate and clear information. Results: The ratio of men to women was equal (1.1/1), with the ≥60 months age group having a higher rate compared to the <60 months group. Rapid pulse accounted for the highest rate (64.4%) among children with arrhythmias, while chest pain and palpitations accounted for the lowest rates at 11% and 13%, respectively. Most of the electrolytes did not have many disturbances. There was 1 case of hypernatremia (accounting for 2.2%) and 1 case of hypokalemia (accounting for 2.2%). There were no cases of chloride disorders. Echocardiograms mostly had abnormal results in pediatric patients with arrhythmias. The most common kind of abnormal result was mitral incompetence (26.7%). Sinus tachycardia accounted for the highest proportion (64.4%) of electrocardiography. Conclusion: The majority of children with arrhythmia were in the age group ≥60 months. Rapid pulse accounted for the highest rate among children with arrhythmias. Most of the electrolytes did not have many disturbances. Cardiac morphological and functional testing mostly had abnormal results in pediatric patients with arrhythmias.
Analisis Geospasial Penentuan Lokasi TPA Sampah di Kabupaten Kerinci
Authors: Susanti Yuli , Triyatno Triyatno
Published: June 2024

The purpose of this research are : 1) To analyze suitable locations for the construction of landfill sites in Kerinci Regency based on SNI Number 03-3241-1994 using a Geographic Information System (GIS), 2) To analyze the suitability of the recommendations for selected landfills based on SNI Number 03 -3241-1994 with Kerinci Regency Regional Spatial Planning (RTRW) Map. This type of research uses quantitative descriptive methods. The results of the research are: 1) the recommended locations for landfill construction are in 3 sub-districts, including Keliling Danau Sub-district with an area of 883 ha, Batang Merangin Sub-district with an area of 1,283 ha, and Siulak Mukai Sub-district with an area of 209 ha. 2) The three selected landfill recommendations are not located in areas planned as residential areas. The three locations that meet the criteria as landfill locations have been planned as plantation areas and permanent production forest areas.
Syarat-syarat dan Prosedur dalam al-Jarh wa al-Ta’dil
Authors: Kurniawan Irwan , Mujoko Bejo , Azzami Abdulloh , Hairullah Hairullah , Arifin Tajul
Published: June 2024

The purpose of this article is to explain the terms and procedures of jarh wa ta'dil. a researcher must have in-depth knowledge of the terms and procedures of jarh wa ta'dil, because the science of jarh and ta'dil includes a discussion of a critic's assessment of the good and bad or defects of the hadith narrator. It is important to know the terms and procedures in jarh and ta'dil because they relate to a hadith and its rawi which is one of the conditions for accepting a hadith.
A clinicoepidemiological study on kala-zar disease from areas infested with the Leishmania donovani in Al-Muthanna province, Iraq
Authors: Alyasiri Ali Jawad , Ali Hasan Hadi
Published: June 2024

Kala azar is a predominant parasitic disease with different clinical manifestations in Al-Muthanna. It represents an important public health problem because of its impact on many individuals, its spread and deaths, as well as the difficulties in applying effective control measures. Therefore, this current study was conducted to describe the demographic and epidemiological features of kala azar disease in the province. A descriptive study was applied to twenty five patients selected from the province, six in Al-Rumaitha Hospital, ten in the Children's Hospital in Al-Samawa, five cases in Al-Khidr Hospital, in addition to four cases in Al- Warka, and these cases were distributed as four in 2016, three in 2017, three in 2018, eight patients in 2019, four patients in 2020 and three patients in 2021. Collect and analyze data such as gender, age, season of infection, time of illness, method of diagnosis, patient outcome, clinical symptoms and place of residence through descriptive statistics. The highest percentage of kala azar was in females by (60 %), and the study showed that the highest percentage of visceral leishmaniasis cases was in January and February, and it began to decline gradually, reaching its lowest rate in August. It was also found that the highest incidence of visceral kala azar was in the age group 1-4 years, while the lowest rate was in the older age group. The geographical distribution of kalazar showed a high percentage of infection in Al-samawa city, with regard to the difference between urban and rural areas, the data revealed the highest recording of cases in rural areas, while the rates were lowest in urban areas. For patients who received health care, the cases of recovery from kalazar were higher by (80%), and it was also noted that the highest percentage of clinical symptoms associated with infection in all patients are spleen enlargement and anemia, followed by enlargement of the liver and lymph nodes in lower rates. Kala azar is likely to affect the rural areas of Al-Muthanna. According to the epidemiological features of visceral leishmaniasis in the county, this disease remains a health hazard and must be managed, under a unified mechanism of control and prevention. Thus, measures such as staff training, screening in endemic areas, and more efforts in rural areas can be beneficial.
Global Shocks and Local Impacts: A CGE Analysis on the Impact of COVID-19 and Russia-Ukraine Conflict on Pakistan's Wheat Sector
Authors: Naveen Tahir  , Khan Ashfaque Hasan
Published: June 2024

Wheat is one of the most important and vital sectors of Pakistan adding around 2% to the country's GDP growth each year. The crop has been in turmoil for the past four years. The primary drivers of this turmoil are the COVID-19 pandemic and the Russia-Ukraine conflict, which have impacted wheat production. The current study employs a Computable General Equilibrium (CGE) model focusing on the individual and combined effects of these two global shock scenarios. The study initiates by exploring the baseline scenario which assumes that there is no existence of Covid-19 or Russia Ukraine Conflict, then the results are calculated firstly for the productivity loss due to pandemic and then due to the Russian Ukraine conflict. Finally, both the productivity shocks are combined to study the shared effect of both the losses. The results indicate that the sector has experienced a significant loss, with spillover effects on its subsidiaries, including flour mills, bakery and confectionary industries, animal feed industries, and processed food industries. The labor and export markets shocks are also simulated highlighting the loss in both sectors attributing to disrupted supply chains and restrictions in covid nineteen and high dependency on Ukraine and Russia wheat imports. Welfare analysis has also been done for all the four scenarios to capture the welfare losses faced in the previous 4 years and the results are compared to the baseline scenario to compare the damage. To mitigate these losses, two policy scenarios are proposed: an expansionary fiscal policy and increased subsidies, followed by increased tariffs and a shift towards locally produced wheat instead of relying on imports.
Pembaharuan Hukum Perkawinan Campuran di Indonesia
Authors: Jekalaya I Wayan , Suradigama I Wayan , Suartini Made
Published: June 2024

Legal relations in Civil Law give rise to legal protection for the parties based on applicable law. Civil law is a set of norms that regulate human relations between the parties themselves and with humans who have an interest in them. Humans have the right to marriage which is reflected in the Civil Code, the 1945 Constitution, and the other Law concerning about Marriage. With the issuance of statutory regulations governing marriage is a manifestation The state pays attention to legal relations, especially marriage, the problem is how to implement mixed marriages in a norm in order to realize legal objectives such as providing justice, legal certainty and benefits.
Type of normative legal research, using normative case studies in the form of legal behavior products. The main point of the study is that law is conceptualized as a norm that applies in society and becomes a reference for everyone's behavior. The conclusion of the discussion in this article is that mixed marriages between Indonesian citizens and foreign citizens are permitted and legal according to the laws in force in Indonesia regarding the citizenship status of husband and wife being able to maintain their citizenship.
The Relationships among Social Stress, Self-Regulation, Addictive Smartphone Use, and Social Media Usage Behaviour of Generation Z
Authors: Shetu Sabakun Naher , Maisha Kashfia , Promi Sadia Islam
Published: June 2024

Despite rising recognition that addictive smartphone use is a significant concern, there has been insufficient study into how social stress, self-regulation, addictive smartphone use, and social media usage relate to Generation Z's overall psychological aspects. The current study focused on Generation Z students in Bangladesh, a developing country, who are now pursuing higher education. The current study aims to provide a quantitative assessment of the linkages between social stress and self-regulation as they relate to addictive smartphone use, which leads to social media usage in both direct and indirect ways. Furthermore, Generation Z's academic performance is regarded as a moderating construct between addictive smartphone and social media usage behaviour. Primary data were gathered using the non-probability, purposive sampling technique. The structured questionnaire survey was completed by 841 Generation Z university students in total. The study model was evaluated using the Smart PLS-SEM software programme. The study's results demonstrated the significant direct and indirect impacts of self-regulation and social stress. According to the results, a mediating relationship is evident. On the other hand, the moderating construct of academic performance did not find any statistical significance. The results of this study add to the body of knowledge about social stress, regulation, addictive smartphone use, and Generation Z's use of social media, particularly in the setting of developing nations. This study also addressed the study limitations and looked at the practical consequences of its findings.