bluuebunny/crossref_metadata_2025 huggingface dataset:
A Novel Model for the Epileptogenic Neural Network Identifying the Pedunculopontine Nucleus as a Key Neuromodulation Target
Authors: Elsawy Ahmad , Valiante Taufik
Published: December 2023

Seizures are a product of parvalbumin interneurons (PVIN) inhibition failure with pyramidal cells (PC) runaway excitation. This dynamic has been implicated in genetic and non-genetic epilepsies, focal and generalized seizures alike. We provide evidence motivating a novel model for the epileptogenic neural network. Our model identifies the pedunculopontine nucleus (PPN) and the thalamus as key nodes that drive and modulate PVIN inhibition in the brain respectively. Our model provides an integrative frame of subcortical and cortical networks involved in ictogenesis. Our model views epilepsy as disruption of PVIN inhibition on top of an ongoing PVIN/PC interplay and compensatory network mechanisms aiming at restoring orderly PC firing. Our model presents the thalamus as a homeostatic node orchestrating these compensatory mechanisms, offering a different perspective than the predominant view of the thalamus as a hub for seizure initiation and propagation. We demonstrate how our model can advance our understanding of the overlapping neural networks of sleep, cognition, consciousness, and epilepsy. Importantly, our model presents the PPN as a key neuromodulation target being the main driver of PVIN inhibition in the brain. We argue that deep brain stimulation of the PPN could potentially offer superior outcomes compared to available neuromodulatory treatments through more direct and efficient targeting of failing PVIN networks in epilepsy.
TRANSFORMASI DIGITTAL DALAM PROSES PENINGKATAN MUTU PENDIDIKAN
Authors: Zahra
Published: December 2023

Transformasi digital memainkan peran yang signifikan dalam peningkatan peran dan mutu pendidikan. Transformasi digital merupakan kekuatan utama yang mendorong perubahan pola pikir pendidikan pada zaman modern ini. Tidak bisa diabaikan bahwa transformasi digital memiliki peran yang penting dalam meningkatkan peran dan kualitas pendidikan. Di era ini, yang terus berkembang dalam hal teknologi, peranan teknologi digital telah memberikan dampak yang signifikan dan mengubah berbagai bagian dalam sistem pendidikan, baik itu mutu, kualitas, serta peran pendidik. Teknologi digital membuat peran para pendidik telah mengalami perubahan signifikan, tidak hanya sebagai instruktur tetapi juga sebagai pengelola pembelajaran yang dapat menggunakan teknologi untuK menciptakan pengalaman belajar yang lebih optimal bagi siswa.
An Investigation of How Angry Reactions to Discrimination by Different Groups Shape Intergroup Discrimination
Authors: Hao Ruohong , Heerdink Marc W , Doosje Bertjan , van Kleef Gerben
Published: December 2023

Intergroup discrimination, as a prominent example of unjust treatment, can elicit negative emotions such as anger. In two experiments (N1 = 301; N2 = 500), we investigated whether anger expressions influence people’s subsequent discriminatory behaviour, and whether this depends on who expresses the anger (victim group, perpetrator group or third party group). We also explored two theoretically-derived candidate mediators of the effects of anger expressions on discriminatory behaviour: empathic responses and perceived discrimination. We obtained partial support for our hypothesis that anger expressions counteract intergroup discrimination, observing the effect in the entire sample of Study 1, but only among women in Study 2. Contrary to the hypothesis, men in that study exhibited the opposite pattern. In Study 1, we observed significant effects of anger expression on perceived discrimination, but no mediation. In Study 2, no effects of anger expression were observed on empathic responses or perceived discrimination. As for the role of anger expressers, differences between conditions were small and unreliable. These findings extend prior evidence supporting the social functions of expressing anger in intergroup contexts, and call for future examination of when, how, and for whom expressions of anger might be beneficial.
Ideologically Incongruent Authoritarianism: Understanding Liberal Right-Wing Authoritarians and Conservative Left-Wing Authoritarians
Authors: Conway Lucian Gideon , Houck Shannon Christine
Published: December 2023

Ideologically incongruent authoritarians – liberal right-wing authoritarians and their counterpart conservative left-wing authoritarians – represent an important yet understudied group. What underlies the incongruence displayed by incongruent authoritarians? How do they differ from congruent authoritarians or members of their own ideological group that do not show incongruent authoritarianism? We present four frameworks for understanding these questions. The first is based on psychological ambivalence – that ideologically incongruent authoritarians are less committed to their ideological liberal or conservative identity, and as such find it easier to shift towards an authoritarianism that is not their own base identity. A second explanation is that both types of incongruent authoritarians represent ideological conservatism. Third, incongruent authoritarians may diverge from others who share their ideology primarily on religious values. A fourth explanation is based on ecological threat models that predict incongruent authoritarians exist due to heightened threat. We examined each of these frameworks using data from 14 studies and over 9,000 participants. Findings offer modest support for all four frameworks, but no framework on its own can offer a comprehensive explanation for incongruent authoritarianism. What is clear, however, is that ideologically incongruent authoritarians in the U.S. comprise a meaningful category with predictable differences from both their fellow non-authoritarian ideologues and their counterpart congruent authoritarians. As such, this work advances our current understanding of authoritarianism, provides unique insight into the psychology of incongruent authoritarians, and contributes to the ongoing asymmetry debate in political ideology.
National Differences in Age and Future-Oriented Indicators Relate to Environmental Performance
Authors: Syropoulos Stylianos , Law Kyle Fiore , Young Liane
Published: December 2023

Environmental concerns inherently involve an intergenerational aspect, where today’s decisions and sacrifices, often with uncertain future benefits, can have far-reaching effects on countless future generations. Numerous national characteristics can forecast a nation’s commitment to investing in environmental sustainability. Hershfield and colleagues (2014) found evidence in support of Gott’s principle, which states citizens may use perceptions of their country’s age to forecast its future continuation. Replicating and expanding these findings, we offer evidence that suggests that a country’s age positively relates to intergenerational solidarity. Further, relevant future-oriented variables, such as a country’s Long-Term Orientation, and Ability to Overcome Temporal Discounting relate to a host of sustainability-related indicators, suggesting that countries concerned about the future exhibit greater concern for the environment. These findings not only reinforce Gott’s principle and replicate prior research but also suggest that framing a country as a long-standing entity and implementing intergenerational framing interventions could be valuable strategies for motivating proenvironmental engagement.
Landslide Susceptibility Mapping Using Analytical Hierarchy Process in Gandaki Province, Nepal
Authors: Subedi Sujan , Bhandari Krishna Prasad , Sherchan Bikash , Neupane Nabaraj
Published: December 2023

Nepal has a diverse geography ranging from the majestic Himalayas to the fertile plains in the Terai and this varied topography makes it susceptible to different hazards. This study analyzed the most recurring destructive natural hazard, i.e., a landslide in Gandaki Province. The result has been presented using Geographic Information System (GIS) based susceptibility mapping employing Analytical Hierarchy Process (AHP). The susceptibility mapping was performed based on 11 conditioning parameters under four groups, mainly topographic factors (Elevation, Slope, Land Use Land Cover and Profile curvature), hydrological factors (Proximity to stream, Precipitation, Drainage Density and Topographic Wetness Index), geological factors (Geology and Fault lines) and infrastructure factor (Proximity to the road). The final result was classified into five classes: shallow, low, moderate, high, and high susceptibility. The validity and accuracy were tested by calculating the areas under the curve (AUC) value of the receiver operating characteristic (ROC) curve. The AUC value of the landslide was found to be 0.793, indicating the model's good performance. The final map can be used for disaster risk reduction, land use planning and early warning systems.
Suitability analysis of PV solar power plant sites in Gandaki province: Application of GIS and Remote sensing
Authors: Bhandari Anish , Pangali Sharma Til Prasad
Published: December 2023

The escalating global demand for energy has triggered a shift towards cleaner alternatives due to mounting environmental concerns. Emerging as a viable substitute, solar power has gained prominence as fossil fuels' adverse impact becomes evident. Historically reliant on hydropower, Nepal is exploring alternative energy sources to mitigate seasonal output variations. Despite abundant renewable resources like biomass, wind, and solar energy, Nepal's energy sector faces funding and technical expertise challenges. Solar energy presents significant promise as a primary renewable source in Nepal, boasting ample sunlight due to its location. However, the current solar capacity remains limited at around 54.6 MW, comprising less than 2.5% of the total installed capacity. The critical factor is the identification of suitable sites for solar power plants. Geographical Information System (GIS) and Multi-Criteria Decision-Making (MCDM) methods have been employed for suitability analysis. This study employs the Analytic Hierarchy Process (AHP), a robust MCDM technique, to assess site suitability. The research is carried out in the Gandaki province, Nepal, encompassing the Himalayan, Hilly, and Terai regions. Criteria like solar radiation, slope, aspect, land use/land cover, proximity to roads, and substations are considered. These criteria are reclassified into suitability categories based on expert opinions and guidelines.  The results indicate areas highly suitable for solar power generation, covering 12.40 km2 (5.64% of the study area), followed by regions least suitable, spanning 7681 km2 (34.93% of the province's area). This research contributes to the effective deployment of solar power by identifying optimal locations for solar power plant construction, thus advancing Nepal's renewable energy goals.
Sketch to Image Translation using Generative Adversarial Network
Authors: Giri Ramchandra , Lamichhane Badri Raj , Pokhrel Biplove
Published: December 2023

Using a Generative Adversarial Network (GAN) has proven its ability to successfully implement realistic images in image translation fields. It has its successful implementation in the sketch-to-image translation, too. Generative adversarial networks are widely used for the purpose of image translation. Most discriminators in generative adversarial networks use encoder or decoder blocks for image segmentation and classification tasks. U-net-based architecture is mostly used in the generator but rarely in the discriminator. If used in the discriminator, it is used for image resolution increment and segmentation tasks. In this research, a U-net-based discriminator is used for image translation tasks. U-net-based discriminator uses local and global differences between the real and fake images, which helps maintain global and local data representation. Resnet-9, used in the generator, uses skip connections, shortcuts, and concatenations, enabling information to flow from earlier to later layers. This helps preserve the original image features and solves the vanishing gradient problems in normal generators. The use of a strong discriminator and effective generator helps in the improvement system's performance. The available dataset was unpaired at the same time. Datasets from various sources were combined and formed a sketch-image pair. The input is a 512x256 human sketch and a corresponding real image pair. The image pair is split into sketch and image with dimensions 256x256. The system's output is the human face image of the corresponding sketch.
Multi-Class Credit Risk Analysis Using Deep Learning
Authors: Paudel Sagun Babu , Devkota Bidur , Timilsina Suresh
Published: December 2023

Credit risk prediction, reliability, monitoring and effective loan processing are the keys to proper bank decision-making. So, understanding the credit customer during the initial loan processing phase would help the bank prevent future losses. In this regard, this study aims to develop a credit risk evaluation model using deep learning algorithms. The model utilizes a credit risk analysis dataset published in Kaggle. The objective is to build deep learning models for predicting credit risk using real banking datasets published on Kaggle. Firstly, data preprocessing and feature engineering are done. Suitable features such as irrelevant and null valued features are identified and removed with techniques like the Karl Pearson correlation, information values, and weight of evidence. Next, data normalization is performed and target features are separated into three classes: high risk, medium risk and low risk. SMOTE-ENN (Synthetic Minority Oversampling Technique with Edited Nearest Neighbor) was applied to balance the dataset. State-of-the-art deep learning algorithms such as GRU (Gated Recurrent Units) Model and Bidirectional Long Short-Term Memory (Bi-LSTM) are implemented to train and learn from the pre-processed data. GRU and Bi-LSTM models performed well, with F1 scores of 0.92 and 0.93, respectively. The result of this investigation illustrates that deep learning models seem promising for evaluating and predicting multi-class problems.
Ways of Developing Creative Thinking and Reasoning of Students in Mathematics Learning
Authors: Dhungana Sandip , Thapa Ramesh
Published: December 2023

Reasoning skill is one of the main components of mathematical competency (NCTM, 2014). Mathematics students use mainly two types of reasoning skills namely imitative reasoning and creative reasoning in solving mathematical tasks. The textbook tasks in our context are of routine types which are solvable using imitative reasoning. Most mathematics teachers use prescribed textbooks in lesson planning and teaching (Thomson & Fleming, 2004) which ultimately promotes imitative reasoning among the students as compared to creative reasoning. Moreover, many mathematics teachers still follow the traditional chalk-and-talk banking pedagogy which does not support the enhancement of creative thinking and reasoning skills. This literature-based research study has identified some of the ways to develop the creative thinking and reasoning skills of mathematics students through the intense study of the available research articles, thesis, and books in the field of mathematical thinking and creativity. This study has found the positive impact of productive struggle and adversity quotient on students’ creative thinking and reasoning skills. Likewise, problem-posing and problem-solving skills have been found to be essential skills for enhancing creativity. This study has also found modern student-centric teaching approaches like the ADI (Argument-Driven Inquiry) approach and the RME (Realistic Mathematics Education) approach beneficial in improving reasoning skills. This study also found CMR (Creative Mathematically Founded Reasoning) tasks to be helpful in increasing the creative reasoning skills of mathematics students.
Philosophical Underpinnings of Tirumantiram
Authors: Srinivasan Ramanathan , Aithal P. S.
Published: December 2023

The current study takes comparative approach to analyze the metaphysical, moral, and mystical aspects of the work known as Tirumantiram written by Tirumular. This paper compares Tirumantiram with various philosophical texts by analysing six key themes of metaphysics, ethics, spirituality, duty, cultural context and linguistic nuances. It exposes inherent commonalities of man’s nature despite cultural differences, allowing for sensitivity regarding universal as well as exceptional conceptual aspects. The study meticulously identifies metaphysical foundations, ethical principles, and spiritual practices, thus enlightening readers on integrated wisdom of world philosophical legacy. Moreover, this exercise adds to scholarly debates and offers practical contributions towards ethical living and spiritual understanding in a pluralistic global village.
ANALISIS PENDAPATAN PEDAGANG KAKI LIMA (PKL) DI KOTA GORONTALO
Authors: Alkatiri Ramlah , Lamusu Agus Salim
Published: December 2023

This study aims to determine 1) the effect of trading time on the income of street vendors in Gorontalo City, 2) the effect of business time on the income of street vendors in Gorontalo City and 3) the effect of business capital on the income of street vendors in Gorontalo City. This research uses a descriptive quantitative approach involving 31 street vendors in Gorontalo City as respondents. The data used are primary data obtained from a questionnaire with Likert scale criteria. The analysis technique uses multiple regression followed by partial hypothesis testing (t test) and simultaneous hypothesis testing (F test), while the data processing used is SPSS version 16. The results of this study indicate that there is a significant effect of trading time, business time and business return as independent variables simultaneously (together) on the income of street vendors as the dependent variable. Meanwhile, the results of the partial test of the hypothesis (T test) indicate that trading time has a positive and significant effect on the income of street vendors, the length of business does not affect the income of street vendors, while working capital has a negative and insignificant effect on the income of street vendors.This study aims to determine 1) the effect of trading time on the income of street vendors in Gorontalo City, 2) the effect of business time on the income of street vendors in Gorontalo City and 3) the effect of business capital on the income of street vendors in Gorontalo City. This research uses a descriptive quantitative approach involving 31 street vendors in Gorontalo City as respondents. The data used are primary data obtained from a questionnaire with Likert scale criteria. The analysis technique uses multiple regression followed by partial hypothesis testing (t test) and simultaneous hypothesis testing (F test), while the data processing used is SPSS version 16. The results of this study indicate that there is a significant effect of trading time, business time and business return as independent variables simultaneously (together) on the income of street vendors as the dependent variable. Meanwhile, the results of the partial test of the hypothesis (T test) indicate that trading time has a positive and significant effect on the income of street vendors, the length of business does not affect the income of street vendors, while working capital has a negative and insignificant effect on the income of street vendors.
Reshaping the Ways of Commerce and Civilization: Modern Construction Machines and the Building of Canada’s Mobility Infrastructure, 1860s–1920s
Authors: Fernandes Gilberto
Published: December 2023

The importance of mobility in Canada’s history can hardly be overstated. The built waterways, railways, and roadways that allowed for the movement of peoples, goods, and ideas within the country have long been considered cultural icons conveying collective ideas of Canadian identity. Yet, little has been written on the history of the modern construction machines that made this mobility infrastructure possible after Confederation, along with their designers, manufacturers, and operators. This article helps fill that gap by examining the technological development, manufacturing, and commercialization of earthmoving equipment in Canada (especially Ontario) in the 1860s–1920s, a period of great construction activity, including two of the world’s largest civil engineering and earthmoving projects and one of the fastest-expanding road networks in North America. It discusses the role of the federal, provincial, and municipal governments in developing, adopting, and disseminating this technology, and their ultimate reliance on American manufacturers despite the National Policy’s protectionism. This article supports the argument that technological development in Canada during the Second Industrial Revolution was continentally integrated in ways that involved technological dialogue with American companies, associations, and publications. While this manufacturing sector became dominated by American corporations by the First World War, the extent to and manner by which that happened varied depending on the type of machinery and the construction sectors in which they were used. The technological transition from steam-powered machines to electric, gasoline, and diesel motors and how it impacted Canadian manufacturers are also discussed.
Epistemological construction doctrine of the veterinary care defect phenomenon in forensic veterinary examination
Authors: Yatsenko Ivan
Published: December 2023

To prove the guilt of a veterinary professional in causing harm to animal health, forensic veterinary examination plays an important role, as the expert’s opinion is a source of evidence in legal proceedings that helps law enforcement agencies or the court to correctly qualify the offence and establish the compliance of certain actions of a veterinary professional with the current legislation. However, the study of the problem of defects in veterinary care is not properly covered in Ukrainian scientific sources. The research aims to formulate a definition of the concept of “defects in veterinary care”, to identify the signs of this phenomenon in the aspect of forensic veterinary examination, to propose a classification of types of defects and to give their characteristics. The methodological basis of the study is a systematic approach due to the specifics of the topic of the work and involving the use of general scientific and special scientific methods, including analysis, synthesis, analogy; logical and semantic method; systemic and structural method; modelling method; comparative legal method. It is proved that a defect in the provision of veterinary care should be considered a situation where a veterinary professional performs poorly diagnostic, therapeutic, tactical, resuscitation, rehabilitation and other procedures, carries out preventive measures, and also performs professional duties improperly or fails to perform them, which causes or may cause negative consequences for the animal(s) in the form of a health disorder (disease, injury, mutilation, etc.) or cause death. The author’s definitions of the concepts of “non-performance or improper performance of professional duties by a veterinary practitioner”, “accident in veterinary practice”, and “professional error in veterinary practice” are proposed and their signs are outlined. It is shown that defects in veterinary care can be caused by both objective and subjective factors. A classification of defects in veterinary care is proposed: by stages of veterinary care, elements and nature of veterinary care, and legal basis. The practical significance of the study is that it forms the basis of the methodology for determining defects in veterinary care during forensic veterinary examination
The role of collective-contractual regulation in ensuring the right of agricultural workers to a safe and healthy working environment
Authors: Novak Tamara
Published: December 2023

The relevance of the study is determined by the need to investigate changes at the international standards level: the inclusion of the right to a safe and healthy working environment in the fundamental principles and rights at work worldwide. This also caused the need for appropriate adjustments to the national legal framework. The second factor of relevance of the study is the novelties of national legislation on collective and contractual regulation of labour and related relations. Analysis of the impact of such changes on the settlement in collective contracts and agreements of the issue of a safe and healthy working environment for people engaged in agriculture, identification of problematic aspects and development of proposals for their overcoming define the purpose of the study. The achievement of this goal was facilitated by the use of a set of methods of scientific knowledge: philosophical (dialectical), general scientific (analysis, synthesis), and special scientific (formal-legal, comparative-legal). As a result of the study conducted, compliance with international standards of changes implemented in Ukrainian legislation regarding the conclusion of collective contracts and agreements was determined. It is proposed to extend the scope of collective agreements to all those who work in agriculture, including members of farms and agricultural cooperatives, to guarantee a safe and healthy working environment and to the work of the most vulnerable categories of workers (women, minors, persons with disabilities). The need to replace the term “labour protection” in Ukrainian legislation with “safety and health of employees at work” is justified since it is more consistent with the object of protection and correlates with international terminology. It is established that the norms of the current industry agreement do not correspond to the needs of the present. It is recommended that the development of the new document reflect in more detail the specific features of measures for the safety and health of employees at work, due to the specific features of production processes in agriculture and the realities of war and post-war times. The results obtained fill the gap in scientific research of the relevant issues, are valuable from the standpoint of the opportunity to apply them in the further reform of legislation on the field of collective-contractual regulation in agriculture, and will also be useful for the preparation of collective agreements of agricultural entities
IMPLEMENTASI PETUNJUK TEKNIS PEMBERIAN BANTUAN OPERASIONAL DAERAH KOTA PROBOLINGGO
Authors: Qodariyah Lailatul , Astuti Veronica Sri , Yudianto Eko
Published: December 2023

Penelitian ini dimaksudkan untuk mengetahui penyelenggaraan dan peningkatkan mutu pendidikan di daerah pemerintah Kota Probolinggo dengan memberikan Bantuan Operasional Sekolah (BOSDA) sesuai dengan kemampuan keuangan daerah. Sekolah penerima BOSDA adalah Sekolah Dasar (SD) Negeri dan Swasta, Madrasah Ibtidaiyah (MI) Swasta, Sekolah Menengah Pertama (SMP) Negeri dan Swasta, dan Madrasah Tsanawiyah (MTs) Negeri dan Swasta. Selain itu peneliti ingin mengetahui implementasi kebijakan BOSDA di Kota Probolinggo terutama terhadap SD berbasis swasta. Metode yang digunakan adalah penelitian kualitatif yang bertujuan untuk menjelaskan fokus dari penelitian ini yang artinya menggambarkan suatu keadaan dengan pendekatan kualitatif atau penelitian yang lebih sesuai dengan mengecek kondisi pada objek penelitiannya. Sedangkan analisis data menggunakan teori George C. Edward III dengan variabel yaitu 1) Komunikasi yang menggunakan penyampaian pesan yang jelas agar tidak terjadi kesalahpahaman tentang subtansi kebijakan dan di perkuat dalam Perwali Kota. 2) Sumber Daya merupakan pendukung sebuah pelaksana kebijakan dengan menggunakan sumber daya manusia, informasi, kewenangan serta fasilitas-fasilitas sebagai indikator mengimplementasikan suatu kebijakan. 3) Disposisi para pelaksana menjadi hal yang mempengaruhi suatu kebijakan dengan menggunakan sikap persepsi, kewenangan, pemahaman, dan komitmen sebagai tolak ukur dalam menerapkan suatu kebijakan, 4) Struktur Birokrasi dikerjakan dengan menggunakan suatu Standard Operating Procedures (SOPs) yang mana hal tersebut bisa membatasi atau juga bisa membuat implementasi yang dilaksanakan memiliki batas pada pelaksanaannya. Hasil menunjukkan BOSDA ini membantu meningkatkan kualitas pendidikan Kota Probolinggo secara perlahan karena tidak banyak yang dapat dilakukan oleh sekolah penerima BOSDA dengan anggaran yang minimal tersebut. Para pelaksana kebijakan ini atau sekolah lebih fokus menggunakan BOSDA pada honor pengajar karena untuk fasilitas dan kebutuhan belajar mengajar lebih banyak menggunakan BOS reguler.
ANALISIS KINERJA PEGAWAI PADA PROGRAM VERIFIKASI SERTA VALIDASI DTKS DI DINAS PEMBERDAYAAN MASYARAKAT DESA DAN SOSIAL KABUPATEN BARITO TIMUR
Authors: Rini Mayang
Published: December 2023

Penelitian ini mengangkat tentang Analisis Kinerja Pegawai dalam Verifikasi dan Validasi Data Terpadu Kesejahteraan Sosial (DTKS) pada Bidang Sosial di Dinas Pemberdayaan Masyarakat dan Desa dan Sosial Kabupaten Barito Timur. Tujuan penelitian pada penelitian ini adalah untuk menganalisis Kinerja Pegawai dalam Verifikasi dan Validasi Data Terpadu Kesejahteraan Sosial (DTKS) pada Bidang Sosial di Dinas Pemberdayaan Masyarakat dan Desa dan Sosial Kabupaten Barito Timur. Kinerja pegawai mempengaruhi seberapa banyak mereka memberikan partisipasi kepada organisasi. Kinerja pegawai dalam hal Penanganan para Penyandang Masalah Kesejahteraan Sosial. Faktanya, masih begitu banyak masyarakat yang belum mampu memenuhi kebutuhan dasarnya, sehingga untuk mencapai hidup layak sangat susah. Di Kabupaten Barito Timur, Bidang Sosial pada Dinas Pemberdayaan Masyarakat dan Desa dan Sosial bertugas untuk mengelola dan meningkatkan pelayanan publik sesuai dengan harapan masyarakat sebagai pelanggan dalam rangka mewujudkan Good Local Government.Berdasarkan hasil penelitian yang dilakukan tentang Analisis Kinerja Pegawai dalam Verifikasi dan Validasi Data Terpadu Kesejahteraan Sosial (DTKS) pada Bidang Sosial di Dinas Pemberdayaan Masyarakat dan Desa dan Sosial Kabupaten Barito Timur. Dapat disimpulkan bahwa, Kinerja Pegawai dalam Verifikasi dan Validasi Data Terpadu Kesejahteraan Sosial (DTKS) pada Bidang Sosial di Dinas Pemberdayaan Masyarakat dan Desa dan Sosial Kabupaten Barito Timur masih belum optimal. Hal tersebut dikarenakan pertama, kurangnya jumlah pegawai yang memberikan layanan kepada masyarakat. Kedua, kurang tepatnya data sasaran penerima bantuan sosial dan ketiga, mekanisme penyaluran bantuan sosial yang masih berbelit-belit.Saran dari peneliti mengenai penelitian ini adalah yang pertama, melakukan penambahan jumlah pegawai di Bidang Sosial, agar dapat meningkatkan kualitas dan kuantitas kinerja. Kedua, melakukan penambahan sarana transportasi agar dapat digunakan secara bersamaan ketika kerja lapangan. Ketiga, peningkatan sarana dan prasarana seperti komputer dan jaringan agar mempermudah pegawai dalam melakukan verifikasi dan validasi data.
Особенности cтруктуры цитомембраны эритроцитов и лимфоцитов периферической крови у детей, проживающих на радиоактивно загрязнённой территории, в отдалённый период Чернобыльской катастрофы
Authors: Stepanova Ye. I. , Vdovenko V. Yu. , Lytvynets O. M.
Published: December 2023

За допомогою методу скануючої електронної мікроскопії проведено дослідження поверхневої архітектоніки еритроцитів і лімфоцитів периферичної крові у дітей, які народилися після чорнобильської катастрофи та проживають в умовах тривалого надходження 137Сs до організму. Встановлено суттєві зміни структури поверхневої цитомембрани еритроцитів і лімфоцитів периферичної крові у дітей основної групи порівняно з контролем. Найбільш виражені зміни виявлено у підгрупі дітей, рівень 137Сs в організмі яких коливався від 6845 до 16522 Бк.
Кореляційний аналіз функціонального стану та артеріального кровотоку печінки у дітей, хворих на хронічний холецистохолангіт
Authors: Hodan V. V.
Published: December 2023

У статті наведені результати залежності між функціональним станом печінки та артеріальним кровотоком у дітей, хворих на хронічний холецистохолангіт. Доведено збільшення показників пігментного та ферментного обміну печінки залежно від зниження швидкості току крові у басейні печінкової артерії. Доведено обернену залежність гіпоальбумінемії від збільшення кутозалежних індексів внутрішнього кровотоку в печінковій артерії.
Особливості дисбалансу мікро- і макроелементів у дітей, хворих на бронхіальну астму, залежно від її контрольованості
Authors: Litvinets L. Ya.
Published: December 2023

Досліджували особливості стану біоелементного складу крові у дітей, хворих на бронхіальну астму (БА), залежно від тяжкості її перебігу. Обстежено 107 дітей віком від 10 до 18 років, хворих на БА в стадії загострення. За результатами застосування тесту контролю астми (GІNA, 2011) за рівнем контрольованості БА дітей розподілено таким чином: 34 (31,8 %) – з контрольованою, 47 (43,9 %) – з частково контрольованою та 26 – з неконтрольованою БА. Біоелементи сироватки крові визначали методом атомно-абсорбційної спектрофотометрії. Встановлено, що при різному ступені контролю за БА зміни проявлялись у зниженні вмісту магнію, цинку при надмірній кількості міді та кальцію. При цьому найбільш виражені прояви дизелементозу виявлено у дітей з неконтрольованою БА: гіпоксичні зміни, енергетичний дефіцит, гіперреактивність бронхів як результат підвищення стресогенної реакції на антиген, зниження антиоксидантного захисту ферментативних систем, дисфункція імунної системи. Виявлені зміни у макро- та мікроелементному складі крові значно знижують резервні можливості імунної системи, індукують хронізацію запального процесу в бронхах, що поглиблює тяжкість перебігу хвороби і зумовлює необхідність диференціальної діагностики, комплексного лікування з урахуванням виявлених дизелементозних станів.
Метаболічний стан та мінеральна щільність кісткової тканини у хворих з хибним суглобом довгих кісток при гіпергомоцистеїнемії
Authors: Bessmertnyi Yu. O.
Published: December 2023

У статті наведено результати дослідження метаболічного стану та мінеральної щільності кісткової тканини у 153 хворих з хибним суглобом довгих кісток, консолідованимпереломом та практично здорових. Встановлено, що порушення репаративного остеогенезу на фоні гіпергомоцистеїнемії супроводжується вираженими змінами функціонального стану кісткової тканини, пригніченням біосинтетичних та посиленням остеоі хондродеструктивних процесів, зниженням мінеральної щільності кісткової тканини з формуванням остеопенії та остеопорозу. Вираженість і спрямованість змін кісткової тканини залежать від типу порушення репаративного остеогенезу.
Прозапальні цитокіни та С-реактивний білок: діагностичні перспективи визначення у сечі хворих на хронічний пієлонефрит
Authors: Lisnyanska I. S. , Yatsyshyn R. I.
Published: December 2023

Обстежено 85 хворих на хронічний пієлонефрит (ХПН) у віці від 26 до 62 років. У всіх хворих визначали вміст С-реактивного білка (СРБ), інтерлейкіну-6 і фактора некрозу пухлин-альфа у крові й сечі за стандартними методиками. При одночасному дослідженні СРБ в крові та сечі хворих на ХПН виявлено високий рівень даного біомаркера в сечі, який перевищував в декілька разів його показники в крові. При вивченні рівня прозапальних цитокінів, які вважають головними індукторами виділення СРБ, встановлено, що підвищення їх концентрації в сечі було більш виражене, ніж у крові, і це підтверджує думку про те, що СРБ може синтезуватися у вогнищі запалення лімфоцитами, макрофагами та ендотеліоцитами. Вивчення рівня цитокінів і СРБ у сечі може бути використано для оцінки вираженості запальних змін у нирці і моніторування ефективності протизапальної терапії.
Дослідження змін геометричних параметрів силіконових відбитків під впливом двох методів дезінфекції
Authors: Nespraydko V. P. , Shevchuk V. O. , Omelyanenko M. D.
Published: December 2023

У лабораторному експериментальному дослідженні оцінювали вплив двох методів дезінфекції на зміни лінійних розмірів силіконових відбитків та виготовлених за ними гіпсових моделей порівняно з незмінними параметрами експериментальної металевої майстер-моделі "Еталон 2". Порівнювали традиційний хімічний метод дезінфекції та фізичний у вигляді мікрохвильової енергії з використанням установки плавного регулювання потужності НВЧ-випромінювання "μ-УндаДент".
Нові підходи до комплексного лікування верхньої мікрогнатії, поєднаної із звуженням зубних рядів
Authors: Malanchuk V. O. , Astapenko O. O. , Chepurnyi Yu. V.
Published: December 2023

У статті описано нові методи хірургічного лікування верхньої мікрогнатії, зокрема при її поєднанні із звуженням зубних рядів. Наведено обґрунтування та описано переваги використання біодеградуючих фіксаторів для остеосинтезу при лікуванні пацієнтів з деформацією середньої зони обличчя.
Комплексна індивідуалізована терапія хворих на сечостатевий хламідіоз з урахуванням порушень прооксидантно-антиоксидантної та імунної систем
Authors: Dasyuk Т. Е.
Published: December 2023

Розроблено новий оригінальний, патогенетично обґрунтований метод комплексного диференційованого лікування хворих на сечостатевий хламідіоз з урахуванням розладів прооксидантно-антиоксидантної та імунної систем, який передбачає індивідуалізоване включення до комплексної терапії сучасного антибактеріального азаліду Азитроміцин та імуномодулятора рослинного походження Манакс з урахуванням особливостей клінічного перебігу захворювання.
Ультраструктура лимфоцитов периферической крови у детей при длительном поступлении в организм радиоактивного цезия
Authors: Stepanova Ye. I. , Litvinets O. M.
Published: December 2023

За методом трансмісійної електронної мікроскопії вивчена ультраструктура лімфоцитів периферичної крові у дітей, які проживають в умовах тривалого надходження 137Cs до організму по харчових ланцюжках. Встановлено істотні зміни субмікроскопічної організації інтрацелюлярних органел, особливо мітохондрій, у дітей основної групи порівняно з контролем. Найбільш виражені зміни спостерігалися в підгрупі дітей з рівнем інкорпорованого 137Cs понад 6845 Бк.
Вроджена вада серця у вагітних – фактор ризику розвитку дистресу плода
Authors: Kyrylchuk M. E.
Published: December 2023

У вагітних з вродженою вадою серця вивчено стан фетоплацентарної системи за допомогою ультразвукової фетометрії, допплерометрії, кардіотокографії, визначення вмісту естрадіолу, прогестерону і плацентарного лактогену у крові і пуповині, патоморфологічного дослідження плаценти. Показано, що вроджена вада серця у матері, ускладнена серцевою недостатністю, – значний фактор ризику розвитку дистресу плода як в доклінічній стадії плацентарної недостатності (порушення матково-плацентарного кровотоку, зміна рівня фетоплацентарних гормонів), так і в поєднанні з клінічними ознаками патології плода (дистрес і затримка його росту).
Дослідження рівня тривожності у хворих з хронічними захворюваннями печінки
Authors: Tkachenko O. V. , Kharchenko N. V. , Korzhenevskyy Yu. L. , Lopuh I. Ya.
Published: December 2023

Наведено результати комплексного неврологічного та нейропсихологічного дослідження з визначенням рівня тривожності серед хворих молодого та середнього віку з хронічним гепатитом та цирозом печінки. У всіх обстежених виявлено підвищений рівень тривожності, який статистично достовірно відрізнявся від рівня тривожності в осіб контрольної групи. Разом з тим рівень тривожності у хворих на хронічний гепатит був нижчим, ніж у хворих на цироз печінки. Частіше в обстежених виявляли середній (з тенденцією як до низького, так і до високого), а також високий рівень тривожності.
Вплив фітотерапії на про- та антиоксидантний статус сперматозоїдів і сім’яної плазми та на імунологічні показники сперми чоловіків з хронічною формою запалення сечостатевого апарата, ускладненого безпліддям
Authors: Tsiporenko S. Yu. , Loskutova I. V.
Published: December 2023

Проведено дослідження продуктів перекисного окислення ліпідів і ферментів антиоксидантного захисту крові у чоловіків з малосимптомними формами хронічного запалення сечостатевого апарата, ускладненого безпліддям. Вивчений цитокіновий статус сперми інфертильних чоловіків. Показано позитивний вплив імупрету в комбінації з гепатомаксом на процеси відновлення активності оксидативної системи, що приводить до поліпшення субпопуляційного складу лейкоцитів сперми, нормалізації концентрацій про- і протизапальних цитокінів і, отже, до збільшення запліднюючого потенціалу.
Пам’яті Анатолія Родіоновича Уваренка
Authors: Friends Colleagues,
Published: December 2023

21 березня 2014 р. на сімдесят дев'ятому році життя перестало битися серце великого сина України, відомого вченого, дбайливого батька, мудрого дідуся та коханого чоловіка Уваренка Анатолія Родіоновича.
Світлій пам’яті Владислави Черних
Authors: Shebeko S. K.
Published: December 2023

Пам’яті лікаря, захисника України, прекрасної дівчини Владислави Черних.
Communication Campaigns for Safer Roads Pakistani Southern Punjab
Authors: Shah Syed Imran Ahmad , Shahzad Muhammad
Published: December 2023

The study aims to examine the efficacy of media communication campaigns for safer roads in southern Punjab of Pakistan. The study employed quantitative methodology and chose a sample of 500 respondents by dividing them into 250 males and 250 females by using convenient sampling.The study analyzed the efficacy of the communication campaigns by law enforcement agencies especially the motorway police for the life safety of the road users. The study concluded that road safety was a general phenomenon and everyone commuting on roads has the right and responsibility of safety. The study concluded that over 60 per cent of males and females were of the opinion that safety helmets should be the mandatory component for all motorcyclists. The study found that all the relevant stakeholders should devise a collective strategy for road safety by involving motorcyclists, drivers of all vehicles, unions, the transport department, police and other persons. This study may open new avenues for the researchers in future to explore phenomena with a broader perspective.
Incorporating the Globalization Paradigm: Effects of Digital Media Usage on Gratification
Authors: Chandio Dastar Ali , Shabbir Taha , Ramzan Muhammad
Published: December 2023

The pervasive influence of digital platforms has seamlessly integrated digital media platforms like WhatsApp into the daily routines of individuals, particularly the youth and students.By conducting an in-depth survey across a diverse cross-section of university students, the study aims to unravel the intricate patterns and multifaceted nature of digital media engagement and its repercussions on various dimensions of pleasure. The study involves into the spectrum of information categories that students interact with, the frequency of their interactions, and the emotional and psychological outcomes stemming from these engagements. The study confines its focus to four prominent public sector universities in Sindh province: Shah Abdul Latif University in Khairpur Mir's, Shaheed Benazir Bhutto University in Nawabshah, Sindh Madrasatul Islam University in Karachi, and the University of Sindh in Jamshoro. The outcomes of this study bear the potential to offer valuable insights to policymakers and shedding light on the benefits and potential pitfalls associated with digital media engagement among students.
Framing War on Terror: Analyzing the Editorials of Mainstream English Newspapers of Pakistan
Authors: Farooq Qaisar Shehzad , Iqbal M. Zafar , Iqbal Ashraf
Published: December 2023

In the aftermath of September 11, Osama Bin Laden has been declared the mastermind of the attacks and al-Qaida and the Taliban has been considered strong outside enemies. In the dusk of 9/11 Global War against Terrorism has been launched by the United States and its allies to counter terrorism in any region and to eradicate extremism from all over the world. Mediated treatment of this un-ended war gives rise to questions that how media prioritize some issues to serve the policy objectives and how media frame events on specific dimensions (Altheide 2007). Pakistan due to its geo-strategic position has attained the status of a front-line state and Pakistani media go hand in hand with mainstream media in War against Terrorism. This study aims to investigate how the Pakistani media frame War on Terror in its editorials toeing foreign policy objectives and international relations of Pakistan with the United States (Abbas 2003).
Post-2021 situation in Afghanistan: Implications on Regional Security
Authors: Adil Nosherwan , Rana Ayesha , Khan Beenish
Published: December 2023

The circumstances in Afghanistan beyond 2021 will have a significant impact on the dynamics of regional security. After foreign forces left Afghanistan, the Taliban took over and the country saw a dramatic political upheaval. Concerns have been expressed by neighboring nations and others over this change in power. The dynamic circumstances present obstacles to the stability of the area, with possible ramifications for commerce, security, and geopolitics. A difficult security environment has resulted from worries of rising terrorism sparked by the Taliban's comeback. As a result of regional powers reassessing their approaches to deal with the shifting circumstances, alliances, and diplomatic relations are becoming less secure. A cooperative regional strategy is required to address common security issues and advance stability in light of the current circumstances. In the post-2021 Afghan environment, fostering a safe and prosperous future requires balancing the interests of diverse stakeholders while navigating the complex geopolitical terrain.
Thirsty Nations, From Conflict to Cooperation: Navigating the Climate Change Implications on Pak-Afghan Hydro-Politics
Authors: Asghar Muhammad Faizan , Nawaz Maryam , Munir Kishwar
Published: December 2023

The security landscape is constantly evolving, encompassing a broader range of non-traditional threats such as environmental, human, food, health, and social security. Water security and related environmental and social threats are significant in this expanded understanding of security. Globalization, urbanization, industrialization, population growth, and the depletion of natural resources pose more realistic risks than conventional military threats. Environmental issues can lead to conflicts between national and local stakeholders, as warned by Ismael Serra Gildin, former Vice President of the World Bank. This article aims to consider water as a non-traditional security threat and explore its impact on Pak-Afghan relations by analyzing water politics' influence and its economic implications for both states. By bridging hydro politics and regional implications, this study paves the way for future research to incorporate the climate perspective in understanding state relations, which is crucial in the current context.
Operation Zarb-e-Azb in the Global Wire Services: A Framing Analysis
Authors: Zafar Abid , Rahman Syed Inam ur , Asif Mariam
Published: December 2023

Pakistan has become a victim of terrorism after its involvement in the ongoing war on terror. The country has lost thousands of civilians and security personnel in this American-led war. Though, Pakistan has always been treated negatively by the media organizations of elite nations. Operation Zarb-e-Azb was a combined military action of the Pakistan army against the armed insurgent groups in North Waziristan which was launched in the year 2014. The current study attempted to examine the framing of Operation Zarb-e-Azb in global wire services. For this purpose, AFP, AP and Reuters were selected. Through the technique of convenient sampling, a total of 300 news items from the entire period of operation were selected for analysis.Quantitative as well as qualitative content analysis and interpretive analysis have been used as a research design for this study. The results indicated that the global wire services framed the news stories of military operations in a positive way. The terrorism and militant threat frame was more dominant in global wires as compared to other frames. The results also revealed that the global wires framed this operation differently by representing the foreign policy and interests of their respective states.