bluuebunny/crossref_metadata_2025 huggingface dataset:
TINJAUAN YURIDIS PERATURAN OTORITAS JASA KEUANGAN (POJK) NOMOR 77 TAHUN 2016 TENTANG LAYANAN PINJAMAN UANG BERBASIS TEKNOLOGI INFORMASI TERHADAP PERJANJIAN PINJAMAN UANG MELALUI FINANCIAL TECHNOLOGY (FINTECH)
Authors: MOHAMMAD ANTON SURYADI  , M. Rizal Efendi
Published: February 2024

Abstract

The issuance of the Financial Services Authority Regulation (POJK) number 77 of 2016 as a form of regulation regarding information technology-based money loans. Financial Technology (Fintech) is the latest innovation in the financial sector which is the locomotive for the development of sophisticated technology. The results of this study indicate that (a) the agreement is valid if it follows Article 1320 of the Civil Code. In an online loan agreement, an agreement that occurs when the creditor / lender and debtor / loan recipient both fulfill their rights and obligations as business actors and consumers where both enter into a loan agreement and as long as the loan agreement does not harm both parties, the loan agreement online is considered legal, (b) a form of legal protection for the parties in an online loan agreement, is the arrangement of the rights and obligations of the parties, such as the rights and obligations of business actors to have the right to get payments from consumers for loans given and are also entitled to get protection against actions of consumers who have bad intentions in carrying out the agreement and the rights and obligations of consumers are regulated in article 4 of law number 8 of 1999. consumers are obliged to pay a certain amount of money for loans that have been ordered from creditors.

This study uses a normative method or study, with the aim of knowing how the implementation and role of the Financial Services Authority Regulation number 77 of 2016 plays a role in protecting the rights of consumers and debtors, therefore researchers are interested in studying it in this study as a form of providing assistance. socialization about online loan agreements so that the public knows about the procedures for online loan agreements, as well as the rights and obligations for business actors and consumers.

So that the formulation of the problem that will be discussed is How is an online loan agreement (credit)? and How is the Legal Protection in Online Money Loan Agreements?

 

Keywords: Financial Services Authority, online loans, Law number 77 of 2016
PERALIHAN HAK ATAS TANAH WARIS KEPADA AHLI WARIS SAAT AKAN DILAKUKAN JUAL BELI
Authors: Rohim Abdur
Published: February 2024

Abstrack

 

Peralihan Hak atas tanah menurut Hukum positif di Indonesia yaitu hak milik menurut Hukum Perdata. Hak milik tersebut sesuai dengan ketentuan konversi dalam UUPA menjadi peralihan Hak atas tanah menurut peraturan pemerintah. Pasal 37 ayat (1) Nomor 24 Tahun 1997. Berdasarkan hal tersebut, maka yang perlu dibahas dalam penelitian ini adalah Mekanisme peralihan hak atas tanah yang bisa dilakukan dibawah tangan kedua landasan peralihan hak atas tanah saat dilakukan transaksi jual beli yang dilakukan dibawah tangan dapat digunakan sebagai alat bukti peralihan hak atas tanah menurut hukum positif di indonesia.

 

Penelitian ini menggunakan tipe penelitian Yuridis Normatif dengan menggunakan pendekatan perundang undangan yang bersifat Konseptual. Kemudian dibantu dengan bahan bahan hukum yang digunakan yaitu bahan hukum Primer dan Sekunder yang di diuraikan, dideskripsikan, dan dianalisis keterkaitan satu sama lain.Tahun 1961 khususnya pada pasal 1 peraturan mentri Agraria Nomor 11 tahun 1961 tentang bentuk akta yang menjelaskan bahwa setiap peralihan hak atas tanah harus dibuat dengan akta pejabat (PPAT). Kedua peralihan hak atas tanah yang dilakukan dibawah tangan sebelum berlakunya PP No. 24 tahun 1997 dapat digunakan sebagai alat bukti peralihan hak atas tanah sesuai dengan ketentuan Pasal 24 tentang pembuktian hak lama PP No. 24 tahun 1997 tentang pendaftaran tanah. Tetapi jika peralihan hak atas tanah tersebut dilakukan setelah berlakunya PP No. 24 tahun 1997 maka peralihan tersebut harus di buktikan dengan Akta PPAT.

 

Kata Kunci: Peralihan Hak atas Tanah Waris
PELAYANAN BADAN PENYELENGGARA JAMINAN SOSIAL KESEHATAN DI DESA PAJARAKAN KULON KECAMATAN PAJARAKAN
Authors: Fathullah Kholidazia El Hamzah
Published: February 2024

Abstract

 

One of the roles of the government towards its citizens in running the government is to provide public services. One of these public services is the BPJS Health service. The purpose of this study is to find out BPJS Health Services to the community using the National Health Insurance in Pajarakan Kulon Village, the benefit is that this research is expected to provide information and knowledge to determine the relationship between BPJS user satisfaction and the Quality of Health Insurance Services. National in BPJS Health. the method used is using the Juridical Empirical method by combining primary and secondary data obtained from the field in the form of interviews and other legal sources. This thesis research is about BPJS Health Services in the implementation of the good governance-based National Health Insurance (JKN) program at BPJS Kesehatan Kraksaan. The conclusions obtained are the categories that exist in BPJS Health Law number 24 of 2011. The advice drawn is that BPJS health users should be able to reach the maximum and make registration easier for new users who want to use BPJS because it will affect the quality of BPJS in BPJS Kesehatan.

 

Keywords: Quality of Health Services, BPJS Health
PENGAWASAN PARTISIPATIF MASYARAKAT UNTUK MEWUJUDKAN PEMILU JUJUR DAN ADIL
Authors: Suryadi Mohammad Anton
Published: February 2024

Abstrack

 

Community participatory supervision as an effort to realize honest and fair general elections is urgently needed to ensure transparency, accountability and integrity in the administration of elections. The essence of the people as holders of electoral sovereignty guaranteed by the constitution has the right not only to elect leaders directly, but also the right to supervise that elections are held without fraud, intimidation or unhealthy political influence. The practice of money politics that often occurs in election contests results in the degradation of democracy in selecting leaders. In the context of democracy, elections are important moments whose integrity must be maintained in order to represent the people's voice in a real way, so that elections are able to realize the people's aspirations to have leaders who have integrity, are competent and are not corrupt. Therefore, community participatory supervision is considered as a form of social control that can monitor and ensure the integrity of elections.

 

Keywords: Monitoring, Community, Election.
Will Environmental Regulations lead to China's outward Foreign Direct Investment?: A Quasi Natural Experiment Based on China's Carbon Emission Trading Pilot Policy
Authors: Cao Yanzhihui , Yin Siyu , Luo Jiabao , Li Deyu
Published: February 2024

Foreign direct investment (OFDI) is an important part of China's "going global" strategy. With the continuous expansion and rapid development of OFDI in China, domestic environmental problems are becoming increasingly severe. Therefore, China has established a pilot policy of Carbon Emission Trading System (ETS) to address environmental issues. This article takes the implementation of ETS pilot policies as a quasi natural experiment, uses the double difference method (DID model) to empirically test whether ETS pilot policies will lead to OFDI, and uses the composite control method for robustness testing to supplement and expand the conclusions of the DID model. In addition, incorporate the "Pollution Shelter Hypothesis" and "Porter Hypothesis" into the same framework to explore the impact mechanism of ETS pilot policies on OFDI. Based on the conclusions drawn, it is recommended to further improve the design of carbon trading systems in pilot areas and establish a national carbon emission trading system to enhance the quality of China's outward foreign direct investment.
Marx and Engels' Educational Thought and Its Innovation and Practice in the New Era
Authors: Lin Feng
Published: February 2024

The educational ideas deeply explored by Marx and Engels in revolutionary practice have strong vitality and important guiding significance. In the context of the new era, socialism with Chinese characteristics further enriches the educational ideas of Marx and Engels, emphasizes the cultivation of morality and clarifies the purpose of education; At the same time, traditional cultural education has been highlighted, and the role of education in cultural inheritance and spiritual construction has been played; The distribution of educational resources has been balanced, and educational equity has been improved; Education reform is also constantly deepening to cultivate innovative talents with innovative abilities. Therefore, we must always prioritize education as a strategic development priority; Deepen the reform of the education system and mechanism to promote the healthy development of education; Strengthening the construction of the teaching staff to safeguard the improvement of educational quality; Emphasize the joint efforts of the Party, government, society, schools, families, and individuals in education.
Tendencias estilísticas en los compositores de la Generación 2000 en el Perú
Authors: Cuentas Sadiel
Published: February 2024

Este texto ofrece un análisis de las tendencias de estilo en los compositores de la Generación 2000 en el Perú, destacando la diversidad y coexistencia de estilos de composición. Se presentan dos ejes principales: el primero abarca desde la música convencional hasta la experimental, y el segundo varía desde la música nacionalista hasta la cosmopolita. De éstos, emergen cuatro categorías: folklorismo modernista, nacionalismo vanguardista, cosmopolitismo y experimentalismo. Estas no son entendidas como movimientos formales, sino como tendencias y enfoques que han surgido de manera no coordinada en el Perú. Se incluyen ejemplos de obras y compositores que representan estas categorías.
ANALISIS KINERJA KEUANGAN PT. BANK RAKYAT INDONESIA (PERSERO) TBK
Authors: Hardianti  , Ismail Badollahi
Published: February 2024

Tujuan Penelitian ini adalah untuk mengetahui kinerja keuangan PT. Bank Rakyat Indonesia (Persero) Tbk., periode 2018-2022. Metode penelitian yang digunakan adalah metode kuantitatif dengan sumber data sekunder. Pengukuran kinerja keuangan ditinjau dari beberapa indikator rasio keuangan yaitu Net Profit Margin (NPM), Return On Asset (ROA), Beban Operasional Pendapatan Operasional (BOPO), Debt to Equity Ratio (DER), Capital Adequacy Ratio (CAR) dan Loan to Deposit Ratio (LDR). Hasil penelitian ini menunjukkan bahwa kinerja keuangan PT. Bank Rakyat Indonesia (Persero) Tbk., periode 2018-2022 yang diukur dengan Net Profit Margin (NPM), Return On Asset (ROA), Beban Operasional Pendapatan Operasional (BOPO) Debt to Equity Ratio (DER), Capital Adequacy Ratio (CAR) dan Loan to Deposit Ratio (LDR) berada dalam kategori sehat (baik).
Borgernes til- og fravalg af daginstitutioner – et conjoint eksperiment
Authors: Damgaard Peter Rasmussen , Hjortskov Morten , Holm Jakob Majlund
Published: February 2024

Borgeres til- og fravalg i velfærdsstaten har store konsekvenser for kvaliteten og indretningen af den offentlige service. Derfor er det også vigtigt for politikere og beslutningstagere at vide, hvilke faktorer der har indflydelse på borgernes til- og fravalg, og hvordan borgerne afvejer dem mod hinanden. Vi undersøger disse spørgsmål i en repræsentativ spørgeskemaundersøgelse, hvor vi beder respondenterne tage stilling til daginstitutionsvalg i et conjoint eksperiment. Resultaterne viser, at de inkluderede faktorer alle har meningsfulde effekter på sandsynligheden for valget af en daginstitution. Dog ser information om, hvorvidt daginstitutionen er offentlig eller privat/selvejende, ikke ud til at have nogen indflydelse. Desuden ser vi på, om en højere andel af uddannede pædagoger kan dæmpe den negative effekt af lave normeringer – det viser sig ikke at være tilfældet.
Failure Study of Rubber-Cord Flexible Couplings and their Mounting Bolts
Authors:   , Gorbačovs Dimitrijs
Published: February 2024

In the Thesis the methodology was developed for preventing the failure of the rubber-cord coupling and its fastening bolts. The methodology was tested on rubber-cord couplings, which are widely used in railway rolling stock. Statistics of failures of rubber-cord couplings and their fastening bolts were collected and studied in detail. The data on pitch angles of rubber-cord coupling was aggregated. One-sided stretching tests of various rubber-cord coupling samples were performed in the RTU laboratory. Load deformation graphs were obtained and the causes of the rubber-cord coupling bolts damage were clarified. Calculations were made using the SolidWorks software, and the search for loads affecting the occurrence of defects in the rubber-cord coupling shell was carried out.
Variational analysis and AI algorithm implementation of free energy landscapes of molecular system
Authors: Du Bo-Chuan , Tian Pu ,   School of Life Sciences, Jilin University, Changchun 130012, China,   School of Artificial Intelligence, Jilin University, Changchun 130012, China
Published: February 2024

Accurate description of the free energy landscape (FES) is the basis for understanding complex molecular systems, and for further realizing molecular design, manufacture and industrialization. Major challenges include multiple metastable states, which usually are separated by high potential barriers and are not linearly separable, and may exist at multiple levels of time and spatial scales. Consequently FES is not suitable for analytical analysis and brute force simulation. To address these challenges, many enhanced sampling methods have been developed. However, utility of them usually involves many empirical choices, which hinders research advancement, and also makes error control very unimportant. Although variational calculus has been widely applied and achieved great success in physics, engineering and statistics, its application in complex molecular systems has just begun with the development of neural networks. This brief review is to summarize the background, major developments, current limitations, and prospects of applying variation in this field. It is hoped to facilitate the AI algorithm development for complex molecular systems in general, and to promote the further methodological development in this line of research in particular.
Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice
Authors: Aubert Nicolas , Purcarea Madeleine , Novarino Julien , Schopp Julien , Audibert Alexis , Li Wangtianrui , Fornier Marie , Cagnet Léonie , Naturel Marie , Casrouge Armanda , Dieu-Nosjean Marie-Caroline , Blanchard Nicolas , Dietrich Gilles , Peirs Cedric , Marodon Gilles
Published: February 2024

CD4+CD25+Foxp3+ regulatory T cells (Treg) have been implicated in pain modulation in various inflammatory conditions. However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysis of the transcriptomes of murine Treg and conventional T cells (Tconv), we observe that the proenkephalin gene (Penk), encoding the precursor of analgesic opioid peptides, ranks among the top 25 genes most enriched in Treg cells. We then present various evidence suggesting that Penk is regulated in part by members of the Tumor Necrosis Factor Receptor (TNFR) family and the transcription factor Basic leucine zipper transcription faatf-like (BATF). Using mice in which the promoter activity of Penk can be tracked with a fluorescent reporter, we also show that Penk expression is mostly detected in Treg and activated Tconv in non-inflammatory conditions in the colon and skin. Functionally, Treg cells proficient or deficient for Penk suppress equally well the proliferation of effector T cells in vitro and autoimmune colitis in vivo. In contrast, inducible ablation of Penk in Treg leads to heat hyperalgesia in both male and female mice. Overall, our results indicate that Treg might play a key role at modulating basal somatic sensitivity in mice through the production of analgesic opioid peptides.
In silico and in vitro evaluation of the anti-virulence potential of patuletin, a natural methoxy flavone, against Pseudomonas aeruginosa
Authors: Metwaly Ahmed , Saleh Moustafa M. , Alsfouk Aisha , Ibrahim Ibrahim M. , Abd-Elraouf Muhamad , Elkaeed Eslam , Elkady Hazem , Eissa Ibrahim
Published: February 2024

This study aimed to investigate the potential of patuletin, a rare natural flavonoid, as a virulence and LasR inhibitor against Pseudomonas aeruginosa. Various computational studies were utilized to explore the binding of Patuletin and LasR at a molecular level. Molecular docking revealed that Patuletin strongly interacted with the active pocket of LasR, with a high binding affinity value of −20.96 kcal/mol. Further molecular dynamics simulations, molecular mechanics generalized Born surface area (MM/GBSA), protein-ligand interaction profile (PLIP), and essential dynamics analyses confirmed the stability of the patuletin-LasR complex, and no significant structural changes were observed in the LasR protein upon binding. Key amino acids involved in binding were identified, along with a free energy value of −26.9 kcal/mol. In vitro assays were performed to assess patuletin’s effects on P. aeruginosa. At a sub-inhibitory concentration (1/4 MIC), patuletin significantly reduced biofilm formation by 48% and 42%, decreased pyocyanin production by 24% and 14%, and decreased proteolytic activities by 42% and 20% in P. aeruginosa isolate ATCC 27853 (PA27853) and P. aeruginosa clinical isolate (PA1), respectively. In summary, this study demonstrated that patuletin effectively inhibited LasR activity in silico and attenuated virulence factors in vitro, including biofilm formation, pyocyanin production, and proteolytic activity. These findings suggest that patuletin holds promise as a potential therapeutic agent in combination with antibiotics to combat antibiotic-tolerant P. aeruginosa infections.
futuro del arte latinoamericano, entonces
Authors: Macchiavello Carla
Published: February 2024

El Coloquio de Arte No Objetual y Arte Urbano celebrado en Medellín en 1981 marcó un cambio importante en la concepción del arte latinoamericano y su teorización futura, esbozando una incipiente postura decolonial. Este ensayo revisa algunas transformaciones en la discusión que mantuvieron intelectuales y artistas durante los años 70s en torno a la identidad del arte y de la teoría del subcontinente, las cuales contribuyeron a dar forma al replanteamiento de los parámetros estéticos y nueva teoría del arte latinoamericano formulada en Medellín.
(Hacia) una crítica de la razón financiera que justifica buena parte del arte de nuestro tiempo
Authors: Sánchez Alberto
Published: February 2024

En los últimos treinta años, las producciones estéticas contemporáneas se han acostumbrado a convivir con ciertas estructuras económicas y determinados comportamientos especulativos que han precarizado algunas de sus potencialidades fundamentales. Este progresivo acomodamiento del arte de nuestro tiempo no es, sin embargo, responsabilidad exclusiva de los artistas, sino también de multitud de agentes, instituciones y organizaciones que han ocultado, subvertido y desactivado todo lo que pasaba por sus manos en aras de una cultura que sustituye la erudición y la reflexión crítica por el simple entretenimiento. Este escrito es un breve repaso a las complicidades y ocultaciones del sistema del arte contemporáneo coincidiendo con un momento histórico complejo y turbulento, la crisis financiera internacional, que puede suponer un interesante punto de inflexión para revertir la situación.
¿Creación artística y generación de conocimientos universitarios?
Authors: Jiménez Victoria
Published: February 2024

No presenta resumen
Tecnologia blockchain sob as lentes da inovação social: evidenciando dimensões em uma fintech social
Authors: Loiola Ricardo Alan Kardec , Lazaro José Carlos , Neutzling Daiane Mulling , Leocadio Aurio Lucio
Published: February 2024

Surgem com relevância no mercado visando, principalmente a desburocratização de serviços financeiros, as “Fintechs”. E neste contexto, a tecnologia “Blockchain” tem emergido consideravelmente. Este trabalho tem como objetivo, evidenciar, como a ação de utilização de Blockchain por uma Fintech Social pode ser visto sob as lentes do constructo de Inovação Social e seus elementos (dimensões). A pesquisa foi descritiva-exploratória. Utilizou-se o método de estudo de caso com análise de conteúdo. A configuração dos elementos (dimensões) baseou-se nos estudos de Tardif e Harrisson (2005), Cloutier (2003) e André e Abreu (2005), seguindo o modelo de Souza, Lessa e Lazaro (2019). As análises iniciais de caráter indutivo, fizeram emergir mais claramente, três dimensões para inovação social: o componente do Caráter, a Inovatividade Social e a Transformação. A relevância desta pesquisa se relaciona com a contribuição para o aprimoramento do conceito e das práticas de inovação social e do desenvolvimento de iniciativas de inclusão econômica social. Concluímos que o acesso ao crédito, com o uso da tecnologia Blockchain, para atender a uma demanda social, valoriza as especificidades territoriais por meio da organização e mobilização de grupos e territórios excluídos e contribui para mudanças em, comportamento, atitudes ou percepções.
Innovation and Tariff-adjustment Options in Public-private Partnerships
Authors:   Universidad Complutense de Madrid (en excedencia), Contreras Carlos , Angulo Julio ,   Independiente
Published: February 2024

This paper explores the question of whether the inclusion in PPP contracts of options to adjust economic conditions in the face of technological changes may help the adoption of such innovations, while reducing the opportunity cost for governments. In the model proposed a grantor government reserves the right to cut its payments to the concessionaire when the concession’s costs are reduced because of the implementation of technological innovations The paper is of interest given that digital transformation and robotization can generate relevant productivity improvements in areas where a significant part of the public budget is spent, such as healthcare and education services. By adopting a numerical example, this paper illustrates the application of the model to a school concession project.
Desafios à criatividade na produção Fast Fashion: um estudo na indústria calçadista
Authors: Hiller Pâmella Diandra Pereira , De Vasconcellos Silvio Luís , Theis Vanessa , Schreiber Dusan
Published: February 2024

O objetivo do estudo é identificar como, em condições de pressão, a criatividade é percebida pelos integrantes de equipes de desenvolvimento de produtos na produção orientada para fast fashion. Foi conduzida uma pesquisa de caráter descritivo, de abordagem qualitativa e como estratégia optou-se pelo estudo de caso único em uma empresa de grande porte, produtora de calçados femininos, na qual foram conduzidas sete entrevistas com pessoas em diferentes posições no desenvolvimento de produtos, aliadas à observação participante. À luz da Visão Baseada em Recursos, a pesquisa é original por avaliar como a criatividade organizacional se desenvolve em setores voltados a produção em larga escala, como é o caso da fast fashion calçadista. O estudo revela que as barreiras a criatividade possuem nuances não completamente reveladas em estudos anteriores, por tratar da criatividade em diferentes níveis organizacionais. O estudo chama a atenção para o ambiente criativo, propondo um olhar mais atento para as motivações intrínsecas e extrínsecas dos profissionais envolvidos com o desenvolvimento de coleções de moda.
Does the nonmarket environment influence procurement strategy in agricultural supply chains?
Authors: Goulart Daniel Franco , Perez Gilberto , Coti-Zelati Paolo Edoardo
Published: February 2024

Nesta pesquisa, exploramos a influência do ambiente não mercantil sobre a estratégia de aquisição. Dado o significativo arcabouço regulatório do setor, a cadeia de suprimentos de biodiesel brasileira foi escolhida como objeto de análise empírica para essa discussão. Através da perspectiva teórica da estratégia não mercantil, este artigo discute como as empresas brasileiras de biodiesel moldam sua estratégia de aquisição de matéria-prima sob a influência da regulamentação do Selo Combustível Social. A coleta de dados foi baseada em entrevistas com profissionais do mercado e não mercantil e observação participativa. As empresas de biodiesel devem moldar sua estratégia de aquisição para comprar matérias-primas de agricultura familiar para cumprir os requisitos do Selo Combustível Social. Altos custos e desafios são notados a partir dessa necessidade. O estudo conclui que a cadeia de suprimentos de biodiesel brasileira constitui uma evidência empírica da relevância do arcabouço teórico da estratégia não mercantil. Portanto, os gestores seniores devem considerar este tópico do ponto de vista da concepção da estratégia. A exploração quantitativa do papel do ambiente não mercantil sobre a estratégia de aquisição pode ser objeto de pesquisas futuras.
O território usado pelo turismo no Rio Grande do Norte
Authors: Almada José Alexandre Berto de
Published: February 2024

O Litoral Norte, uma das regiões internas do Polo Costa das Dunas, é composto por sete municípios. A sua atividade turística é um desdobramento direto do turismo desenvolvido em Natal, capital do estado do Rio Grande do Norte. Levando em consideração a atividade turística no Litoral Norte, o presente artigo tem como objetivo identificar a evolução econômica do turismo e sua contribuição para a organização do espaço (a região e seus municípios) a partir da participação do Estado, do mercado e dos turistas. A partir do número de empregos e empresas turísticas, contratos de repasses e demanda turística, apresenta-se e se aplica o Índice de Território Usado pelo Turismo com vistas a estabelecer um quadro comparativo entre os sete municípios do Litoral Norte e avaliar o nível de território usado por essa atividade, bem como sua contribuição para o desenvolvimento econômico municipal. Os resultados mostram que o território usado pelo turismo na região do Litoral Norte não se materializa de forma homogênea, sendo mais importante para o desenvolvimento econômico para alguns pontos do território e inexpressiva para outros.
Palavras-chave: Geografia do turismo; Índice de Território Usado pelo Turismo; Litoral Norte; Rio Grande do Norte; território usado.
Agroecologia e sistemas alimentares de uma perspectiva multidimensional da sustentabilidade
Authors: Barancelli Marcia Domenica Cunico , Bezerra Islandia , Perondi Miguel Angelo
Published: February 2024

O presente artigo tem como objetivo relatar uma experiência acadêmica de imersão agroecológica nos sistemas alimentares da perspectiva multidimensional da sustentabilidade, com vista a contribuir para as reflexões sobre desenvolvimento sustentável, soberania alimentar e Segurança Alimentar e Nutricional. Trata-se de um relato de experiência a partir das metodologias ativas de ensino do Programa de Pós-Graduação em Sociologia da Universidade Federal do Paraná, realizada em dezembro de 2019. Na análise considerou-se a perspectiva multidimensional da sustentabilidade (econômica, social, ecológica, cultural, política e ética). As evidências indicam que orientar agroecossistemas para um desenvolvimento sustentável gera padrões de produção e consumo sustentáveis e, consequentemente, promove transformação social. O conhecimento científico complexo permeia o contexto agroecológico, permitindo identificar relações positivas entre agricultura familiar, soberania alimentar, Segurança Alimentar e Nutricional e o desenvolvimento sustentável dos territórios.
Palavras-chave: Agroecologia; desenvolvimento sustentável; Segurança Alimentar e Nutricional; sistemas alimentares; soberania alimentar.
Café, indústria e desenvolvimento regional no estado de São Paulo
Authors: Sá Porto Paulo Costacurta de , Utsunomiya Kleber
Published: February 2024

Este artigo tem o propósito de demonstrar que o processo de mudança da economia estadual de São Paulo, que ocorreu ao longo do século XX, passando de uma economia cafeeira para uma economia mais diversificada, deu-se em conformidade com o que prevê a Teoria da Base Exportadora. Isto pode ser evidenciado pelo uso de indicadores da participação do café e de outros produtos na pauta de exportações de São Paulo, mostrando como ocorreu a evolução da economia paulista no período que vai de 1915 até 2020. Pode-se observar que, após exibir seu domínio entre 1915 e 1928, o café perderia paulatinamente sua preponderância nas exportações paulistas, aos poucos sendo substituído, em consequência da diversificação da base de exportação, por outros produtos, principalmente, produtos industrializados, incluindo maquinaria e veículos, mas também produtos vegetais, como açúcar e suco de laranja.
Palavras-chave: Café; desenvolvimento regional; economia regional e urbana; São Paulo; Teoria da Base Exportadora.
Políticas públicas de desenvolvimento territorial e multifuncionalidade: estudo de caso em Curitibanos/SC
Authors: Bosetti Cleber José
Published: February 2024

Este artigo tem como objetivo analisar os desdobramentos da política de expansão universitária do Programa REUNI sobre o desenvolvimento territorial no município de Curitibanos, no estado de Santa Catarina. A expansão universitária no município deu-se com a instalação do campus da Universidade Federal de Santa Catarina (UFSC) no ano de 2009. A pesquisa que deu origem a este artigo consistiu de um estudo de caso, realizado em duas propriedades rurais do entorno do campus, por meio da realização de entrevistas semiestruturadas com os proprietários, bem como do levantamento de dados secundários sobre o desenvolvimento socioeconômico do município. Os resultados indicam que as propriedades estudadas, devido ao aumento da procura de moradias por parte dos estudantes, tornaram-se multifuncionais, e que há uma correlação entre a expansão universitária e a ampliação das perspectivas de desenvolvimento rural e territorial no município.
Palavras-chave: Curitibanos/SC; desenvolvimento territorial; multifuncionalidade; políticas públicas; Universidade.
Economic Assessment of Specialized Ingredient-treated Feed for Crossbred Dairy Cattle in Subtropical Climates
Authors: Yadava Dhawal Kant , Gaur Parth , Kansal Garima , Chandel Rahul Singh , Bhartib Panch Kishor
Published: February 2024

This experiment aimed to reduce the cost of feeding dairy cattle that were crossbred using a total of twenty-four crossbred animals. Four groups of six animals each were randomly selected from among the animals. Group 2 (76% treated feed), Group 3 (49% treated feed), Group 4 (100% treated green fodder), and Group 4 (Control) made up Group 1 (Gr-1). The remaining feed A-1, A-2, A-3, A-4, A-5, and A-6 received 1.5% urea+5% molasses+0.5% salt, 1.5% urea+5% molasses+1.5% salt, 1.5% urea+10% molasses+1.5% salt, 5% molasses+0.5% salt, and 10% molasses+0.5% salt were applied, respectively.  Each animal at the farm cost 81Rs to feed on average. By contrast, under typical conditions, the feeding expenses for the first group in the A1, A2, A3, A4, A5, and A6 groups were 35, 35, 67, 71, 36, and 70 rupees, respectively. There was a decrease of 43, 42, 11, 11, 44, and 10 rupees as a result. In the second group, the reduction for the A1, A2, A3, A4, A5, and A6 treatment groups was 30Rs, 29Rs, 10Rs, 9Rs, 30Rs, and 10Rs, respectively. In the third group, the reduction was 19Rs, 18Rs, 5Rs, 4Rs, 21Rs, and 7Rs, respectively.
Comparative Effects of Garcinia kola and Garlic Extracts on Some Liver and Haematological Functions in High Salt Diet-Induced Hypertensive Wistar Rats
Authors: Osuji Chigozirim A. , Kalu Achi Ngozi , Obioma Ohaeri Christopher , John Ohiagu Chukwuemeka
Published: February 2024

Garcinia kola is commonly consumed in Nigeria in social ceremonies, while Garlic is commonly used as a spice in the preparation of certain foods. In this study, the protective effects of extracts of the plants against a high salt diet (8% NaCl) induced hypertension were investigated in rats. Extracts prepared from the plants were subjected to phytochemical screening for acute and sub-acute toxicity studies in rats. In the protective study against salt-induced hypertension thirty-five adult male rats assigned to seven groups of five rats were treated such that,  group one served as the normal control group, and group two was the hypertensive control group. Groups three to six were administered graded doses of extracts respectively after induction. While group seven received a combination of the two extracts after induction. Treatment commenced after confirmation of hypertension and lasted for two weeks before animals were sacrificed to collect blood for biochemical and haematological analysis. Results obtained showed that G.kola and Garlic feeding produced in rats following liver and haematological assays as values of these parameters in the test groups did not significantly differ from control values (p<0.05).
Monitoring the Impacts of Artificial Recharge Structures on Water Table at Ambedkar Nagar, Uttar Pradesh, India
Authors: Singh Sonveer , Sherring Arpan
Published: February 2024

To study the groundwater recharge through rainfall and artificial recharge structures in selected dry well in different locations of UP was experimented. The data was recorded (1998-2017) to execute the artificial recharge structure at the appropriate locations with best geological condition to enhance the recharge rate at least cost for control of declining groundwater level. Study reveals that the stochastic auto regressive lime series model is an effective tool for management of ground water resource at pre and post monsoon. The variation of pre and post monsoon ground water level is maximum as the physical soil characteristics including hydraulic conductivity may enhance the recharge rate at least cost.
Comparison of Practical Learning and Theoretical Learning a Study to Investigate Benefits and Challenges
Authors: Sattorova Zilola I.
Published: February 2024

The process of acquiring knowledge to better comprehend the various disciplines we will use in our daily lives is known as education. "Education" encompasses both the information we learn and experience outside of books and classrooms, as well as the knowledge we acquire and experience in our homes, schools, and as members of society. A specialized education modifies people's thoughts, emotions, and behaviors so they can contribute to their own well-being and improve their communities. Additionally, education prepares a person for the challenges of life by forming their character, thoughts, and interpersonal cooperation. Learning alters our outlook on life, and education is crucial for both individual and societal advancement. Currently, though, there are two ways to further your education: theoretically and practically. The advantages and difficulties of both kinds have been covered in this article.
Toxic Cyanobacteria in Greek Freshwaters, 1987—2000: Occurrence, Toxicity, and Impacts in the Mediterranean Region
Authors: Cook Catherine M. , Vardaka Elisabeth , Lanaras Tom
Published: July 2004

In a survey in Greece from 1987 to 2000 hepatotoxic cyanobacterial blooms were observed in 9 out of 33 freshwaters. Microcystins (MCYSTs) were detected by HPLC in 7 of these lakes, and the total MCYST concentration per scum dry weight ranged from 50.3 to 1638 ± 464 μg g—1. Cyanobacterial genera (Microcystis, Anabaena, Anabaenopsis, Aphanizomenon, Cylindrospermopsis) with known toxin producing taxa were present in 31 freshwaters. From our data and a review of the literature, it would appear that Mediterranean countries are more likely 1) to have toxic cyanobacterial blooms consisting of Microcystis spp. and 2) to have higher intracellular MCYST concentrations. A case study in Lake Kastoria is used to highlight seasonal patterns of cyanobacterial and MCYST‐LR occurrence and to assess cyanotoxin risk. Cyanobacterial biovolume was high (> 11 μL L—1) throughout the year and was in excess of Guidance Level 2 (10 μL L—1) proposed by WHO for recreational waters and Alert Level 2 for drinking water. Further, surface water samples from April to November exceeded Guidance Level 3, with the potential for acute cyanobacterial poisoning. Intracellular MCYST‐LR concentrations (max 3186 μg L—1) exceeded the WHO guideline for drinking water (1 μg L—1) from September to November with a high risk of adverse health effects. Preliminary evidence indicates that in 3 lakes microcystins are accumulated in some aquatic organisms. Generally, a high risk level can be deduced from the data for the Mediterranean region.
Water Quality Monitoring of Tropical Ponds: Location and Depth Effect in Two Case Studies
Authors: Mukhopadhyay Gautam , Mondal Debasis , Biswas Pinaki , Dewanji Anjana
Published: July 2004

The variability in water chemistry of samples taken on a monthly basis (March 1999 to February 2000) from two shallow tropical ponds was studied. The effect of location and pond depth on water chemistry was also examined. The study demonstrated that intraannual variability in nutrient concentration is high. Thus, a high annual sampling frequency is required to provide representative annual mean water quality data. Routine monitoring during the monsoons is important for studies on dissolved oxygen and macrophyte growth. Significant differences were found between the topmost and bottommost points for samples of dissolved oxygen collected from the deepest part of both ponds. For nutrient analysis (nitrogen and phosphorus), sample from any location was found to be representative of the whole pond.
Effect of Nickel and Cadmium on Ammonium Uptake Kinetics of Free and Immobilized Cells of Anacystis nidulans
Authors: Awasthi Mamta , Chand Rai Lal
Published: July 2004

The stress effect of Ni and Cd on the ammonium uptake varied significantly (ANOVA test) in free and immobilized state of the test organism. The effect due to the interaction between different variables (cell state type, metal type and metal dose) was studied to depict the significant or non‐significant variation in the ammonium uptake by free and immobilized cells in the presence of metal ions. Ammonium uptake exhibited a competitive mode of inhibition in the presence of Ni in both free and immobilized state of the organism. However, Cd exhibited non‐competitive and competitive inhibition in free and immobilized cells, respectively. The study demonstrates that there is a considerable influence of metal ions on the ammonium uptake. Cd was found to be more toxic compared to Ni in both free and immobilized state.
Sorption of Iron on Surfaces: Modelling, Data Evaluation, and Measurement Uncertainty
Authors: Meinrath Günther , Merkel Broder , Ödegaard‐Jensen Arvid , Ekberg Christian
Published: July 2004

Assessment of the likely outcome of engineered invention strategies in acid mine drainage often involves complex geochemical modelling activities. Geochemical modelling is based on chemical thermodynamic data. In addition sorption models, kinetical reaction rates and transport tools are included into the modelling codes because the interactions between solution components and surfaces, reaction time and transport are considered important features characterising the site‐specific situation. In the determination of both thermodynamic data and sorption coefficients, speciation calculations play an important role. By applying the probabilistic speciation code Ljungskile to some simplified acid mine drainage scenarios, the strong impact of chemical speciation on the complete measurement uncertainty budget of geochemical modelling predictions is shown. The complete measurement uncertainty budget in combination with other metrological concepts like traceability is an essential element of quality assurance for experimental data. The elements of quality assurance are provided by international agreements and normative documents on national and international levels. The following discussion will focus on some metrological issues of sorption data.
Coagulation Efficiency and Residual Aluminum Content of Polyaluminum Silicate Chloride in Water Treatment
Authors: Gao Baoyu , Yue Qinyan , Wang Bingjian
Published: July 2004

A series of polyaluminum silicate chlorides (PASC), which have different OH—/Al and Al/Si molar ratios, has been prepared by a copolymerization technique and a composite technique, after which the coagulation efficiency and the residual aluminum content of PASC for water treatment were compared with polyaluminum chloride (PAC) by jar test. The experimental results show that PASC has better coagulation efficiency and lower residual aluminum content than PAC, and the PASC prepared by the copolymerization technique gives a better coagulating effect than that prepared by the composite technique. In addition, the OH—/Al and Al/Si molar ratios have some effect on the coagulation effect and residual aluminum content of PASC in treated water. With increasing OH—/Al molar ratio and decreasing Al/Si molar ratio, the residual turbidity and residual aluminum content in treated water diminishes. The pH of the water sample also affects the residual aluminum content of the water and there is a lower residual aluminum content in the neutral pH range.
Molecular understanding of oxygen‐tension and patient‐variability effects on ex vivo expanded T cells
Authors: Haddad Hadar , Windgassen Dirk , Ramsborg Christopher G. , Paredes Carlos J. , Papoutsakis Eleftherios T.
Published: July 2004

Immunotherapy with ex vivo cultured T cells depends on a large supply of biologically active cells. Understanding the effects of culture parameters is essential for improving the proliferation and efficacy of the expanded cells. Low oxygen tension (5% pO2) was previously reported to improve T‐cell expansion and alter cellular phenotypic characteristics compared to T cells cultured at 20% pO2. Here we report the use of DNA‐array based transcriptional analysis coupled with protein‐level analysis to provide molecular insights into pO2 and patient‐variability effects on expanded primary human T cells. Analysis of seven blood samples showed that reduced pO2 results in higher expression of genes important in lymphocyte biology, immune function, and cell‐cycle progression. 20% pO2 resulted in higher expression of genes involved in stress response, cell death, and cellular repair. Expression of granzyme A (gzmA) was found to be significantly regulated by oxygen tension with cells at 5% pO2 having greater gzmA expression than at 20% pO2. Protein‐level analysis of gzmA was consistent with transcriptional analysis. Granzyme K (gzmK) was coexpressed with gzmA, whereas Granzyme B (gzmB) expression was found to precede the expression of both gzmA and gzmK in 15‐day cultures. Temporal gene expression patterns for seven blood samples demonstrate that most genes are expressed by all patient samples in similar temporal patterns. However, several patient‐specific gene clusters were identified, and one cluster was found to correlate well with cell proliferation and may potentially be used to predict patient‐specific T‐cell expansion. © 2004 Wiley Periodicals, Inc.
Direct injection HPLC micro method for the determination of voriconazole in plasma using an internal surface reversed‐phase column
Authors: Péhourcq F. , Jarry C. , Bannwarth B.
Published: July 2004

A direct plasma injection liquid chromatographic method has been developed for the determination of a new triazole antifungal agent, voriconazole, using an internal surface reversed phase column. Therapeutic drug monitoring of voriconazole is relevant for patient management, especially in the case of drug–drug interaction. The method is easy to perform and requires 10 µL of a plasma sample. The chromatographic run time is less than 9 min using a mobile phase of 17:83 v/v acetonitrile–potassium dihydrogen phosphate buffer, 100 mm, pH 6.0 and UV detection at 255 nm. The ﬂow rate was 1 µL/min. A linear response was observed over the concentration range 0.5–10 µg/mL (r2 = 0.977). A good accuracy (bias ≤ 7.5%) was achieved for all quality controls, with intra‐day and inter‐day variation coefﬁcients inferior to 6.7%. The lower limit of quantitation was 0.2 µg/mL, without interference of endogenous components. The stability of voriconazole in plasma stored at different temperatures was checked. Finally, the possibility of direct injection of plasma samples into the column permits a reduction in reagent consumption and in analytical steps, and hence in analytical error. Copyright © 2004 John Wiley & Sons, Ltd.
Screening for pyrrolizidine alkaloids in plant materials by electron ionization RP‐HPLC‐MS with thermabeam interface
Authors: Mroczek Tomasz , Baj Stefan , Chrobok Anna , Glowniak Kazimierz
Published: July 2004

Plant samples from leaves of Cerinthe minor, Cynoglossum clandestinum, Echium tuberculatum (as well roots), Eritrichium rupestre, Lithospermum purpureo‐coerulem, Nonnea lutea, Nonnea setosa, Onosma stellulatum and Cynoglossum amabile were screened for toxic pyrrolizidine alkaloids (PAs) with a newly elaborated procedure comprising gradient HPLC with diode array (DAD) and thermabeam electron impact mass spectrometry (EI‐MS). Dried plant material was extracted with boiling 1% tartaric acid in methanol for 2 h on an electric basket and crude extracts puriﬁed with cation‐exchange solid phase extraction (CE‐SPE). Puriﬁed extracts containing alkaloids were separated on Zorbax SB RP18 stationary phase in gradient of 0.1% formic acid in methanol. The ﬂow rate was 0.25 mL/min and was suitable both for DAD and EI MS detections. Applied gradient procedure permitted quite sufﬁcient separation of PAs in various plant extracts. On the basis of EI MS spectra, toxic PAs with unsaturated 1,2‐double bond in the necine moiety were found in all plant materials and in nine of them (excluding only Cynoglossum amabile) for the ﬁrst time. They included the following types of structures: 9‐ and 7‐viridiﬂoryl‐retronecine monoesters, 9‐angeloyl‐7‐viridiﬂoryl‐retronecine, 9‐angeloyl‐retronecine diester, 9‐viridiﬂoryl‐retronecine saturated ester, 7‐angeloyl‐9‐viridiﬂoryl‐retronecine, 7‐angeloyl‐9‐echimidinyl‐retronecine, trachelanthamine and others. Selected ion monitoring (SIM) chromatograms at m/z 119, 120 and 136 together with analysis of UV spectra from DAD detector can be applied in rapid screening for toxic PAs in new plant extracts but to obtain detailed structural information (molecular weight and stereochemistry) more expensive hyphenation is required. Consumption of all analysed plants should be avoided as carcinogenic and hepatotoxic properties of the alkaloids detected are expected. Copyright © 2004 John Wiley & Sons, Ltd.
Simultaneous determination of albiﬂorin and paeoniﬂorin in rat urine by solid‐phase extraction and high‐performance liquid chromatography following oral administration of Si–Wu decoction
Authors: Sheng Yuxin , Li Lie , Zhang Jinlan , Guo Dean
Published: July 2004

A high performance liquid chromatographic method (HPLC), together with solid phase extraction (SPE), was developed for simultaneous determination of albiﬂorin and paeoniﬂorin in rat urine after oral administration of Si–Wu decoction. The samples were pretreated with solid phase extraction using Extract‐Clean™ cartridges. Analysis of the extract was performed on a reversed‐phase C18 column and a mobile phase made up of acetonitrile and 0.03% formic acid (17:83, v/v). UV detection was set at 230 nm. The assay was linear over the range 2.625–52.50 mg/mL for albiﬂorin and 3.875–77.50 µg/mL for paeoniﬂorin. The average percentage recoveries of three spiked urines were 97.01 ± 3.32 and 102.32 ± 6.97 for albiﬂorin and paeoniﬂorin, respectively. The intra‐day precision (RSD) ranged from 0.21 to 1.79% at concentrations of 4.20, 10.50, 26.25 and 39.375 µg/mL of albiﬂorin and 0.12 to 2.92% at concentrations of 3.875, 10.85, 23.25 and 58.125 µg/mL of paeoniﬂorin, and inter‐day precision (RSD) was from 1.02 to 1.86% for albiﬂorin and 0.94 to 3.30% for paeoniﬂorin, at the same four concentrations. This method was applied in order to analyze albiﬂorin and paeoniﬂorin in rat urine following oral administration of traditional Chinese medicinal preparation of Si–Wu decoction. Copyright © 2004 John Wiley & Sons, Ltd.