bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the Inhibition Effects of Natural Terpenoids on Toxoplasma gondii Tachyzoites
Authors: Jiang Zi-Yang , Dong Kai , Huang Zheng-Song , Yuan Chang-Chun , Liu Bo , Chen Qi-Wei , Chen Jian-Ping
Published: June 2022

Background
At present, the preferred method for the clinical treatment of toxoplasmosis is still drug therapy such as pyrimethamine and sulfadiazine, but there are problems such as large side effects and drug resistance. Terpenoids are distributed in nature and a large number of studies have shown that they have effective inhibitory effects on various parasites.
Methods
In this study, we used small-molecule intermediate products of natural terpenoid chlorajaponilide C to evaluate their cytotoxicity and their intracellular and extracellular inhibitory effects on Toxoplasma gondii tachyzoites.
Results
We demonstrated that two of these target compounds could induce tachyzoite apoptosis probably by altering tachyzoite mitochondrial membrane potential, calcium homeostasis, and lipid metabolism, effectively reducing the number of extracellular tachyzoites. In addition, the two target compounds were also able to effectively clear intracellular tachyzoites, possibly enhancing this effect by interacting with the host cell's immune system.
Conclusions
Two terpenoid natural products with low cytotoxicity had direct and indirect anti-toxoplasma effects and were expected to further evaluate their potential for the treatment of toxoplasmosis.
Plant-mediated synthesis of CuO nanoparticles with Allium ampeloprasum extract; application as a glucose non-enzymatic electrochemical sensor
Authors: Eskandari Mobina , Norouzi Banafsheh
Published: June 2022

A simple synthesis using Allium ampeloprasum plant extract as a reducing agent has been done for the preparation of CuO nanoparticles (CuO NPs). Firstly, copper ions are reduced to copper atoms by plant extract, and then, they could be changed to CuO during calcination. Some techniques such as X-ray diffraction (XRD), UV-Visible (UV-Vis), Fourier-transform infrared (FT-IR), scanning electron microscopy (SEM), and electrochemical methods have been applied to the evaluation of the CuO NPs formation. A modified carbon paste electrode with CuO (CPE/CuO) was prepared and employed for the non-enzymatic amperometric sensor of glucose. The linear dynamic range of this modified electrode and the limit of detection (LOD) were 1-120 μmol L-1 and 0.8 μmol L-1 (3δ), respectively. Simplicity, low cost, and easily of preparation are the prominent features of this sensor. Also, the stability, reproducibility, and repeatability of this modified electrode are acceptable.
Subclinical systolic and diastolic myocardial dysfunction in polyphasic polymyositis/dermatomyositis: a 2-year longitudinal study
Authors: Péter Andrea , Balogh Ágnes , Csanádi Zoltán , Dankó Katalin , Griger Zoltan
Published: June 2022

Background: Cardiac involvement in patients with idiopathic inflammatory myopathies (IIM) is associated with increased morbidity and mortality risk, however little is known about the progression of cardiac dysfunction and long term data are scarce. In the present work we intended to prospectively study echocardiographic parameters in patients with IIM for two years.Methods: 28 IIM patients (43.9±1.6 years) without cardiovascular symptoms were enrolled. Patients with monophasic/polyphasic disease pattern were studied separately and compared to age-matched healthy individuals. Conventional echocardiographic and tissue Doppler imaging (TDI) parameters of systolic [LV: ejection fraction (EF), mitral annulus systolic movement (MAPSE), lateral s') and diastolic left (mitral inflow velocities, lateral anulus velocities: e', a', E/e') and right ventricular function (fractional area change: FAC, tricuspid annulus plane systolic excursion: TAPSE) were measured at the time of the diagnosis and 2 years later.Results: Subclinical LV systolic dysfunction characterized by reduced lateral s’ (10.4 vs. 6.4 cm/sec, p<0.05), EF (62.6±0.6%, vs. 51.7±0.7%) and MAPSE (18.5±0.6 vs. 14.5±0.6 mm) could be observed in IIM patients with polyphasic disease course two years after diagnosis compared to controls. Furthermore, diastolic LV function showed a marked deterioration to grade I diastolic dysfunction at 2 years in the polyphasic group (lateral e': 12.9 ±0.6, vs. 7.4±0.3 cm/sec; lateral a': 10.7±0.3, vs. 17.3±0.8 cm/sec; p<0.05) supported by larger left atrium (32.1±0.6 vs. 37.8±0.6 mm; p<0.05]. TDI measurements confirmed subclinical RV systolic dysfunction in polyphasic patients two years after diagnosis (FAC: 45.6±1.8%, vs. 32.7±1.4%; TAPSE: 22.7±0.5, vs. 18.1±0.3 mm; p<0.05). Similar, but not significant tendencies could be detected in patients with monophasic disease pattern. Polyphasic patients showed significantly (p<0.05) worse results compared to monophasic patients regarding EF (51.7±0.7% vs. 58.1±0.6%), lateral s’ (6.4±0.4 cm/sec vs. 8.6±0.4 cm/sec,), left atrium (37.8±0.6 mm vs. 33.3±0.8 mm), FAC (32.7±1.4% vs. 41.0±1.6%) and TAPSE (18.1±0.3 mm vs. 21.3±0.7 mm). Conclusions: Significant subclinical cardiac dysfunction could be detected in IIM patients with polyphasic disease course two years after diagnosis, which identify them as a high risk population. TDI is a useful method to detect echocardiographic abnormalities in IIM complementing the conventional echocardiography and can recognize the high cardiac risk.
WITHDRAWN: A Systemtic Review on Gait Measurement Techniques Using Prisma 2009
Authors: Rathore Radheshyam
Published: June 2022

Academics and prosthetics are interested in gait evaluation since it is a highly focused research field. There is a lot of literature in this field because it is a popular diagnostic tool for measuring abnormalities and the beginning of musculoskeletal illnesses. Although there are several gait measurement Techniques (GMT) for motion analysis in the literature, there are only a few studies that indicate the comparative analysis and applicability of different methodologies. The goal of this work is to give a useful recapitulation of various gait assessment methods and to investigate the relative prevalence of various GMT based on several researchers' applications.
The findings of a comprehensive review of gait measurement methods utilising the PRISMA methodology are summarised in this publication. A total of 53 research articles published between 1989 and 2021 were considered for critical review. The categories of gait measurement systems were compared and ranked using the Analytic Hierarchy Process, based on particular criteria (AHP). The review helps to summarise many areas of gait analysis, including task kinds, gait characteristics, and gait measurement techniques. The study compares gait assessment methods using a specially created capacity index and gives appropriate mappings between these aspects. It also includes helpful advice for choosing gait systems depending on the criteria.
Clarification of white-fleshed guava juice by a fixed-angle conical rotor centrifuge laboratory and characterization of continuous disk stack centrifuges
Authors: Ninga Kombele Aime , Desobgo Steve Carly Zangue , De Sirshendu , Nso Emmanuel Jong , Kayem Joseph
Published: June 2022

The two objectives of this paper were to determine the effect of centrifugation parameters on guava juice physicochemical characteristics and to identify operational characteristics of continuous disc-stack centrifuges based on the performance of a laboratory centrifuge. Effects of g-force (149g – 3731g) and centrifugation time (10 – 40min) on juice physicochemical characteristics (protein, pectin, galacturonic acid, dry matter, total soluble sugars contents; pH; electrical conductivity, clarity and particle size distribution) were assessed. Laboratory centrifuge performance was evaluated for 1343g, 2388g and 3731g. At 1343g, separation limits (xmax), feed flow-rates of disc-stack centrifuges and cut-off sizes (x50) were determined for corresponding laboratory centrifuge operation times. Significant decrease in average particle size, protein and pectin contents was observed, contrary to juice clarity. Similar clarification efficiency was obtained for g-forces ≥ 1343g. xmax were 2669nm, 2200nm and 1783nm, with corresponding x50 for continuous centrifuges, 1887nm, 1556nm, 1261nm, for 20min, 30min and 40min, respectively.
A Novel Decision-Making Method for Selecting Charging Pile Manufacturer with q-Rung Dual Hesitant Information
Authors: Tan Mengwei , Shang Xiaopu , Wang Jun , Xu Yuan
Published: June 2022

In recent years, the development of electric vehicles has received extensive attention. However, how to choose a suitable charging pile manufacturer for electric vehicles is a matter of concern. The selection of charging pile manufacturers involves many factors, and it is hard for decision makers (DMs) to provide accurate assessments due to the uncertainty of subjective or objective factors. As a combination of q-rung orthopair fuzzy set (q-ROFS) and dual hesitant fuzzy set (DHFS), q-rung dual hesitant fuzzy set (q-RDHFS) provides more possibilities for information expression and gives DMs greater decision-making freedom. Because of the advantages of q-RDHFS in expressing uncertain information, we propose a novel decision method to capture DMs’ hesitant information with q-rung dual hesitant fuzzy elements (q-RDHFEs) to obtain the optimal scheme. Firstly, Frank t-norm and t-conorm (FTT) is well known for its flexibility in coping with compatibility compared to traditional algebraic operation. Considering the advantages of FTT, we extend FTT to q-RDHFS and provide the definition of Frank operational rules of q-RDHFS. Subsequently, according to generalized power average (GPA) and generalized power geometric (GPG) operators, some corresponding operators based on the novel operational laws are proposed. Then, with the proposed operators, a novel multi-attribute decision-making (MADM) method under q-RDHFS environment is introduced and applied to the selection of charging pile manufacturers. Finally, compared with the existing methods, the method proposed in this paper can better handle extreme evaluation information and is more flexible in operation.
Fatty Acid Metabolism-related Genes in Bronchoalveolar Lavage Fluid Unveil Prognostic and Immune Infiltration in Idiopathic Pulmonary Fibrosis
Authors: Lyu Yin , Guo Chen , Zhang Hao
Published: June 2022

Background: Idiopathic pulmonary fibrosis, often abbreviated as IPF, is a condition that is both chronic and progressive, and has an unfavorable prognosis. Recent research has demonstrated that individuals with IPF exhibit characteristic alterations in the fatty acid metabolism in their lungs, suggesting an association with the disease pathogenesis. Here, we explored whether the gene signature associated with fatty acid metabolism might be used as a reliable biological marker for predicting the IPF patients' survival.Methods: Data of fatty acid metabolism-related genes (FAMRGs) were extracted from the Kyoto Encyclopedia of Genes and Genomes (KEGG), Hallmark, and Reactome databases. The GSE70866 data set was retrieved for information on individuals diagnosed with IPF. Next, a consensus clustering approach was used to discover novel molecular subgroups. Then, Gene Set Enrichment Analysis (GSEA) was conducted to evaluate the mechanisms involved. CIBERSORT was utilized to ascertain the infiltration levels of immune cells in the identified subgroups premised on specific gene expression signatures of immune cells. Finally, the Least Absolute Shrinkage and Selection Operator (LASSO) algorithm and multivariate Cox regression analysis were utilized in the development of a prognostic risk model.Results: The patterns of gene expression that are linked to fatty acid metabolism were used to construct two subgroups that had remarkably different prognoses. GSEA indicated that immune-related pathways, were significantly altered between the two subgroups, and different subgroups had different metabolic characteristics. Poor prognosis was associated with high immune cell infiltration, particularly activated NK cells, monocytes, and activated mast cells. A risk model that was developed premised on FAMRGs showed excellent significance for use in predicting IPF. The prognosis for individuals diagnosed with IPF might be correctly predicted using a nomogram that incorporated clinical features and the risk model.Conclusion: The proposed fatty acid metabolism-related gene signature is a potential biological marker for predicting the clinical outcomes and infiltration status of immune cells, and may ultimately increase the accuracy of treating patients with IPF.
Zwischen Ablehnung und Befürwortung
Authors: Zala-Mezö Enikö , Egli Johanna , Häbig Julia
Published: June 2022

Im Beitrag werden kollektive Orientierungen aus Gruppendiskussionen mit der dokumentarischen Methode rekonstruiert und daraus abgeleitet, welche Positionen die Gruppen zum Umgang mit digitalen Medien beziehen. Die Gruppendiskussionen wurden wenige Monate nach dem durch die Corona-Pandemie bedingten Lockdown geführt, der eine bereits bestehende Erwartung – Schulen sollten digitale Medien im Unterricht einsetzen – deutlich verstärkt hat. Aus schulentwicklungstheoretischer Sicht wird gefragt, wie die Schulen mit dieser verstärkten Erwartung umgehen und wie sich die Gruppen diesbezüglich positionieren. Vor dem Hintergrund praxistheoretischer Annahmen lassen sich sowohl Veränderungs- als auch Stabilisierungstendenzen hinsichtlich des Einsatzes digitaler Medien ausmachen. Die Ergebnisse weisen darauf hin, dass dabei keine linearen, sondern komplexe Dynamiken zwischen Orientierungen und Erwartungen entstehen, die den im öffentlichen Diskurs entstandenen Leitsatz ‹Krise als Chance› relativieren. Die Gruppendiskussionen – je eine aus sieben Schulen – wurden mithilfe der dokumentarischen Methode ausgewertet. Im Beitrag werden drei typische Positionierungen im Spektrum zwischen Ablehnung und Befürwortung digitaler Medien vorgestellt. Die Ergebnisse zeigen, wie Schulen zwischen einem Festhalten an Bisherigem und einer Öffnung gegenüber Neuem oszillieren und ihre schulischen Praktiken jeweils aushandeln.
FACTORS OF IMPACT ON FINANCIAL SECURITY OF HOUSEHOLDS IN CONDITIONS OF PANDEMIC CRISIS
Authors: Zakharkin O. , Chukhno R. , Inshina N.
Published: June 2022

Today, households are the basis of the state's economic system, an important source of investment resources, a key factor in the formation of effective demand, which is the key to the successful operation of economic entities and the formation of state and local budgets. At the same time, during the pandemic crisis, many households found themselves in a difficult situation due to rising unemployment, declining incomes, and the emergence of additional medical expenses. Therefore, the financial security issues of households have become particularly relevant and require immediate solutions both at the level of the household and the state as a whole. The purpose of this work is to study the essence of financial security of the household and the factors that affect it, the development of modern theoretical and methodological approaches to assessing the level of financial security of households and finding effective ways to ensure it. The article analyzed the general situation of households in Ukraine in recent years and found that their number is gradually declining due to general negative demographic processes and the loss of part of the territory. The analysis of recent research and publications on the financial security of households has allowed to systematize the approaches of various authors to the definition of this concept and its content and form their own vision of its essence. The place of the household in the system of relations with other economic entities was determined, which is a prerequisite for its successful functioning and development. As a result of the study, external and internal factors influencing households' financial security in the current conditions of the pandemic crisis were identified. A dynamic analysis of the nominal GDP per household, the ratio of deposit rates, and inflation over the past few years. According to the leading rating agencies, the quality of life of the population of Ukraine was analyzed. The internal factors influencing the financial security of households were also studied, such as level of education, financial literacy, qualification, the level of economic activity of the household, the level of rational use of resources. As a result, it was determined that most of the factors considered hurt the financial security of households, which has increased in a pandemic.
ANALYSIS OF OBSTACLES AND SUCCESS FACTORS OF INNOVATION COMMERCIALIZATION
Authors: Shcherbachenko V. , Kotenko S.
Published: June 2022

The article presents the results of a study of the prospects for the commercialization of innovations and the factors hindering their development. The purpose of the study is to identify factors that contribute to the market success of innovation, as well as to examine the barriers that hinder the innovation of enterprises and do not allow to achieve the desired effect. To achieve this goal it is necessary to implement the following tasks: to conduct a bibliometric analysis of the relationship of factors of commercialization of innovation, to explore the negative factors contributing to the failure of innovation, to identify obstacles to innovation at different stages, and to determine factors of successful commercialization of innovations. The main research methods that were used in writing the article are comparative analysis of scientific publications and research on the work of commercialization of innovations, synthesis, generalization, and visualization map by VOSviewer software.
With the help of the VOSviewer software product, a visualization map was created in connection with the concept of "commercialization of innovations" and related ideas, based on information from the Scopus database. In the process of working on the article, literary sources were analyzed, which are close to the research topic. The results of the analysis confirmed the theory of factor influence on the effectiveness of commercialization of innovations. Both internal and external factors that directly and indirectly affect the results of innovation and opportunities to increase its profitability were identified. Groups of clusters formed as a result of the construction of visualization maps reflect additional factors that are insufficiently studied in the thematic scientific literature. Such factors, when further analyzed, can be the subject of new research and can help determine their specific impact (positive or negative) on the end result of the commercialization of innovation. Moreover, we have defined that innovation commercialization process has a number of practical advantages: economic, social, competitive, market benefits for companies, consumers, society in large.
ECONOMIC VALUE ADDED AS AN INDICATOR OF EVALUATION FUNCTIONING EFFICIENCY OF A COMPANY
Authors: Hrytsenko L.L. , Derkach L.S.
Published: June 2022

Article focuses on analyzіng of the definition company economic value added relevance. Corporate management is a rather complex and versatile process. It must be based on accurate and constructive data. Accounting calculations are not a clear indicator of the state of the company in some cases. Because they don`t provide sufficiently meaningful information on the real efficiency of economic activity. As a result, it is difficult for owners and shareholders to determine the real economic value of companies in today's economic environment. Therefore the use of the EVA concept is becoming so popular. However, the question of its validity is still relevant for discussion all over the world. So, we are faced with the aim of studying the theoretical and practical principles of using economic value added as an important financial management indicator to evaluate the efficiency and development of the company.

It describes the basis of the emergence of this concept. It is proved that EVA indicator modeling is an effective tool of the general system of financial management at the company. The benefits that owners, shareholders, management and potential investors receive when using EVA indicator are identified. The main is a real understanding of the efficiency of the company. The study compared EVA to other alternative tools for similar purposes and identified it as both simple and effective. The formulas for calculating the indicator are given. All of them are reduced to determining whether the profitability of the company covers the costs incurred and whether there is a formation of value added. On the basis of formulas, a constructive method of EVA calculation is constructed. It is found that the result determined in the calculation process may be lower than zero or equal to it in the case of unproductive management. What means that values above zero and positive dynamics are the most desirable for the company. The steps of application of the concept for strategic planning are presented. It is determined which components of the EVA model should be influenced to optimize and increase the value of EVA indicator.
A Clinical Audit and Impact of Interventions on Antibiotic Prescribing Practices at a Public Dental Primary Care Clinic
Authors:   Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, Universiti Malaya, 50603 Kuala Lumpur, Malaysia, Lim Sarah Wan-Lin , Awan Diana Brennai ,   Grace Chieng Dental Clinic, CH206, Jalan Batu Kawa, Batu Kawa, 93250 Kuching, Sarawak, Malaysia, Maling Thaddius Herman ,   Samarahan Divisional Dental Office, Lot 7993, Block 59, Level 1, Kota Samarahan New Township, 94300 Kuching, Sarawak, Malaysia
Published: June 2022

Inappropriate antibiotic prescribing in dentistry has been widely reported but local studies are scarce. We aimed to evaluate antibiotic prescribing practices among dental officers in a public dental primary care clinic against current guidelines: specifically assessing the number, appropriateness, accuracy of prescriptions, type of antibiotics prescribed and repeated prescribing of the same type of antibiotics within a specific duration. A retrospective audit consisting of two cycles (1st cycle: July to September 2018, 2nd cycle: July to September 2019) was carried out by manually collecting relevant data of patients (aged 18 and above) who were prescribed antibiotics from carbon copies of prescription books. Between each cycle, various interventions such as education through a continuous professional development (CPD) session, presentation of preliminary findings and making guidelines more accessible to dental officers were implemented. When the 1st and 2nd cycles were compared, the number of antibiotic prescriptions issued reduced from 194 to 136 (–30.0%) whereas the percentage of appropriate prescriptions increased slightly by 4.1%. Inaccurate prescriptions in terms of dosage and duration decreased (–0.5% and –13.7%, respectively) whilst drug form and frequency of intake increased (+15.7% and +0.7%, respectively). Repeated prescribing of the same antibiotics by the same officer within a period of ≤6 weeks no longer occurred. Amoxicillin and metronidazole were most commonly prescribed in both cycles. Overall, the antibiotic prescribing practices did not closely adhere to current guidelines. However, clinical audit in conjunction with targeted interventions resulted in improvement in the antibiotic prescribing patterns. Thus, further intervention and re-audit is necessary.
Periodontal Diseases among Pregnant Women in Kuching, Sarawak
Authors:   Periodontic Unit, Jalan Masjid Dental Clinic, Ministry of Health Malaysia, 93400 Kuching, Sarawak, Malaysia, Ahmad Aisah , Jaafar Mohamad Adib ,   Periodontic Unit, Sibu Jaya Dental Clinic, Ministry of Health Malaysia, 96000 Sibu, Sarawak, Malaysia,   Periodontal Specialist Clinic, Polyclinic Mak Mandin, Ministry of Health Malaysia, 13400 Butterworth, Pulau Pinang, Malaysia
Published: June 2022

Epidemiological and longitudinal studies have shown that pregnancy is associated with increased gingival inflammation and worsening of periodontal status. Prospective studies suggested that periodontal therapy during pregnancy might reduce the risk of adverse pregnancy outcomes and significant periodontal status improvement. The objectives of this study were to evaluate the prevalence of periodontal disease amongst pregnant women, and to compare periodontal conditions before and after non-surgical periodontal therapy. This study was a cross-sectional and intervention study of pregnant women at the Mother and Child Health Clinic, Jalan P. Ramlee, Kuching, who were referred to the Periodontic Unit, Jalan Masjid Dental Clinic, Kuching for further periodontal examination and treatment. All participants were examined and diagnosed with healthy periodontium or diseased periodontium. Sixty women became the subjects and 85% were diagnosed with periodontal disease, while 15% had healthy periodontium. Plaque score (PS) and bleeding score (BS) were evaluated at baseline and at eight weeks. At baseline, all periodontal parameters (mean ± SD) were higher in the diseased periodontium group compared to the healthy group (BS, 39.6 ± 21.5 vs 6.5 ± 3.9; PS, 46.4 ± 30.1 vs 33.5 ± 31.1). After two months, both groups showed improvement in all periodontal parameters; diseased periodontium (p = 0.001) and healthy periodontium group (p = 0.016). In conclusion, 85% of the participants in this study had periodontal diseases and, the non-surgical periodontal therapy improved the participants’ periodontal status. Furthermore, there was no significant adverse pregnancy outcomes reported in this study.
Clinical Effectiveness of Composite Resin Bonded with Universal Adhesive for the Restoration of Non-Carious Cervical Lesions Using Air Abrasion: A Randomised Controlled Trial
Authors:   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, Karnataka 575001, India, Reddy Shanthana , Mandadi Lohith Reddy ,   Department of Periodontics, SB Patil Dental College and Hospital, Bidar, Karnataka 585401, India, Mala Kundabala ,   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, Karnataka 575001, India, Abhinav T.N. ,   Department of Public Health Dentistry, Sri Sai College of Dental Sciences, Vikarabad, Telangana 501102, India, Dave Aabha ,   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, Karnataka 575001, India, Thomas Manuel S ,   Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, Karnataka 575001, India
Published: June 2022

Restorative treatment is very challenging for non-carious cervical lesions (NCCLs) due to functional and structural complexities. The purpose of this randomised controlled trial (RCT) was to evaluate the clinical performance of nanocomposite restorations bonded using universal adhesive in self-etch mode with and without air abrasive surface treatment for NCCLs. A total of 70 NCCLs, from a group of consenting patients who fulfilled the inclusion criteria, were recruited for the study. The study was carried out following CONSORT guidelines. Block randomisation was done for equal allocation of lesions into; Group 1 (surface treatment with alumina air abrasion) and Group 2 (control group without mechanical surface treatment). The lesions were restored with nanocomposite using a universal bonding agent in self-etch mode. The clinical performance of the restorations was evaluated by two examiners using modified United States Public Health Service (USPHS) criteria at baseline, 3 months, 6 months and 12 months. A Chi-square test was performed for inter-group comparison. Cochran’s Q test and Dunn’s post hoc analysis were used for intra-group comparison. The inter-group comparison revealed no statistically significant difference between the experimental and control group for all the parameters assessed. With the intra-group analysis, it was found that there was a significant decrease in the performance of the restorations concerning marginal staining, marginal adaptation and surface texture during the evaluation period (p < 0.05). However, all of them demonstrated clinically acceptable performance. According to the results of this RCT, it was concluded that airborne particle abrasion of NCCLs did not improve the clinical performance of nanocomposite resin bonded using universal adhesive.
Nudged elastic band calculations of the (4H)SiX hydrogarnet type defect in Mg2SiO4 forsterite
Authors: Poe Brent T. , Perna Maria Grazia
Published: June 2022

First-principles calculations based on density functional theory (DFT) using the generalized gradient approximation (GGA) were performed to assess the energetic barriers separating different topological configurations of the (4H)SiX hydrogarnet type defect in Mg2SiO4 forsterite with the climbing image nudged elastic band (CI-NEB) method. Barrier heights are low (<0.6 eV) with respect to typical activation energies observed for H-diffusion but more comparable to those for electrical conductivity of H2O-bearing nominally anhydrous minerals. As can be expected, hydrogen bonding to O atoms both within the defect and belonging to adjacent tetrahedra plays a fundamental role in the stability of each configuration. Saddle points along the minimum energy path (MEP) typically correspond to the transition of one hydrogen bond breaking to form a new hydrogen bond such that one or more OH bonds have shifted in direction without themselves breaking. MEPs show that slightly out-of-plane torsional hopping from one configuration to another can reduce the height of the barrier. We illustrate several different reaction coordinates between symmetry equivalent pairs of configurations and non-symmetry related pairs that can result in an effective means of local charge transport by shifting the center of mass of the (4H)4+ cluster within the defect site without proton transfer to an interstitial site. Especially at low temperatures in the absence of thermally activated processes that result in the breaking of stronger chemical bonds, these types of configurational transformation mechanisms are likely to be important contributors to the dielectric behavior of nominally anhydrous silicate minerals and also affect both electrical conductivity and electrical conductivity anisotropy when investigated by AC methods such as impedance spectroscopy. The NEB method can also be used to examine more effective charge and mass transport processes that involve the dissociation of the hydrogarnet defect into more complex chemical species, which might involve similar hydrogen bond breaking and forming processes observed in this study along with more significant atomic displacements.
Timelike transition form factor for CP-odd Higgs boson production
Authors: Sasaki Ken , Uematsu Tsuneo
Published: June 2022

We investigate the production of CP-odd Higgs boson
A^0A0
associated with a real \gammaγ
in e^+e^-e+e−
collisions. Because of the properties of A^0A0
coupling to the other fields, the main contribution comes from the
top-quark triangle loop diagrams. We obtain the “timelike” transition
form factor which describes the production amplitude of
A^0A0
in the e^+e^-e+e−
collisions. This timelike transition form factor is related to the
spacelike transition form factor relevant for the
A^0A0
production in e^-\gammae−γ
collisions. It turns out that the possible extra contributions from
chargino-sneutrino and neutralino-selectron box diagrams do not give
sizable effects.
Background field method and generalized field redefinitions in effective field theories
Authors: Quadri Andrea
Published: June 2022

We study the non-linear background field redefinitions arising at the
quantum level in a spontaneously broken effective gauge field theory.
The non-linear field redefinitions are crucial for the symmetric
(i.e. fulfilling all the relevant functional identities of the theory)
renormalization of gauge-invariant operators. In a general
R_\xiRξ-gauge
the classical background-quantum splitting is also non-linearly deformed
by radiative corrections. In the Landau gauge these deformations vanish
to all orders in the loop expansion.
La potencia de juntarse: un acercamiento al proceso de colectivización de las mujeres trans en la Calle de las Guapas
Authors: Castaño Urdinola Jessica Tatiana
Published: June 2022

En Manizales las Guapas se configuran como un colectivo social porque comparten existencial y políticamente en razón de unos significados comunes que tienen que ver con el ser mujeres trans, ser trabajadoras sexuales, ser pobres, nombrarse de una misma manera, habitar un mismo espacio, concebir el cuerpo como un territorio en transformación, reconocerse como sujetas de derecho que pueden interpelar al Estado, entre otros que se disputan cotidianamente entre ellas mismas y con otros actores sociales e institucionales.
El agente educativo en la garantía de la protección integral de la primera infanciai
Authors: Restrepo Segura Yusty Carolina , García Peña John Jairo
Published: June 2022

Al identificar los aportes investigativos sobre el rol que ejercen los docentes de primera infancia para la garantía de la protección integral en la niñez, se evidenciaron las brechas en la garantía de la protección integral a la infancia, las cuales surgendesde el mismo núcleo familiar, desde el Estado por la dificultad de cumplir con esta labor, por la falta de corresponsabilidad social frente a los niños y la recarga en los docentes como principales actores en este proceso. Aunque el agente educativo, esun actor significativo para el desarrollo integral de los niños, no puede recaer en su quehacer toda la responsabilidad de la protección a la primera infancia, es necesario articular esfuerzos estatales que comprometan otras instancias institucionales y actores sociales, que posibiliten brindar servicios educativo - formativos a la primera infancia, propiciar y recrear espacios para la participación de las familias y de personas significativas en las acciones orientadas a la Protección infantil.
Tendencias metodológicas para la inclusión social de tecnologías apropiadas en zonas rurales
Authors: Ducuara Molina Ingrid , Gutiérrez Malaxechebarría Álvaro , Zafra Mejía Carlos Alfonso
Published: June 2022

Este artículo tiene por objetivo estudiar las tendencias metodológicas a nivel mundialde tecnologías apropiadas (TA) desarrolladas en zonas rurales con inclusión social. Se realiza una revisión sistemática en bases de datos científicas. Se identifican las principales metodologías (cualitativas, cuantitativas y mixtas), herramientas y enfoques en procesos rurales con TA. Se detectan también los principales factores (social, técnico, económico, ambiental, institucional y cultural) y variables de estudio en procesos de TA rurales. Los continentes con un mayor número de experiencias en TA rurales son África y Asia. El sector de energía asocia el 56,0% de las experiencias detectadas.
Tramitación del sufrimiento social en Colombia: una mirada a las experiencias comunitarias desde las víctimas del conflicto armado
Authors: Serrano Mora Sandra Milena
Published: June 2022

La reflexión se plantea desde las formas de tramitación del sufrimiento social producto de la violencia política en Colombia, recogiendo las experiencias locales y comunitarias. Se desprende desde el análisis de contenido realizado a partir de tres tesis de pregrado en el área de la Psicología Social. Se plantean categorias: elaboraciones simbólicas, memoria o liderazgo social, como formas de tramitación y resistencias comunitarias. Las comunidades del dolor se erigen como comunidades de esperanza y apoyo mutuo. Se reafirma el compromiso etico-político de las Ciencias Sociales, frente a la construcción de conocimiento desde las voces y comunidades dolientes, reconociendo saberes otros.
La reducción voluntaria del consumo como oportunidad de desarrollo a escala humana
Authors: Cabrales Salazar Omar , Marquez Vargas Florentino , Sanabria Rangel Pedro Emilio
Published: June 2022

Se plantea hoy, la posibilidad de ampliar espacios de intercambio de mercancías que rebasen la visión estrecha del consumismo inspirado en el capitalismo salvaje; entre ellas, la posibilidad del No Consumo como opción válida para establecer procesos alternativos de crecimiento económico, sobre todo en los países latinoamericanos, que incorpore otros saberes y lógicas de mercado para el intercambio de bienes y servicios. Aspectos centrales de la propuesta alternativa de reducción del consumo voluntario (“No Consumo”) se presentan además como estrategia para que el ser humano pueda construir escenarios que propendan por la satisfacción de necesidades, la equidad en el bienestar y el empleo; para reconvertir a las empresas, adaptando sus líneas de producción a esquemas que mitiguen el impacto sobre el medio ambiente y para promover mercados regionales latinoamericanos que fomenten la recuperación, la reutilización, el reciclaje y la reparación.
El Paran Pan Pan “Fin de la Pobreza” en Cartagena de Indias, periodo 2012-2019
Authors: Márquez Guzmán José
Published: June 2022

En este trabajo se analizan los indicadores de pobreza monetaria en Cartagena de Indias durante el periodo 2012-2019, en comparativa nacional y, teniendo como eje primordial el Objetivo de Desarrollo Sostenible (ODS) 1 “Fin de la Pobreza”. Siendo Cartagena una de las principales ciudades de Colombia que cuenta con tres poderosos sectores de ingresos económicos (Industrial, Turístico y Portuario), y que describen a una ciudad fortalecida económicamente, sus resultados no se traducen en un avance proporcional para la reducción de la pobreza monetaria.
A su vez, se examina la incidencia de los planes de desarrollo distritales (PDD) ejecutados en el mismo periodo como hoja de ruta de la política pública para combatir la pobreza monetaria.
El estudio está basado en el análisis de los datos que arrojan los indicadores y la revisión de los PDD 2012-2019, en lo concerniente a la pobreza monetaria. La exploración documental se realizó teniendo en cuenta las líneas de base de la población a intervenir, los recursos distribuidos en los planes de desarrollo y las indagaciones del marco legal de la política pública nacional enfocados a nivel territorial para disminuir la pobreza. Esto permitió mostrar el impacto de la articulación de los PDD con la hoja de ruta global encaminada a fortalecer los indicadores socioeconómicos del distrito. El principal reto es consolidar una política de protección social estable, y volverla una de promoción social, en la que las personas puedan fortalecer sus capacidades de manera constante, mejorando sus ingresos, lo que conlleva a recomendar un modelo de intervención social que pueda combatir la realidad de la pobreza en Cartagena de Indias.
Palabras clave: pobreza; políticas públicas; plan de desarrollo; impacto social; modelo de desarrollo.
Factores clave para colaborar con las micro, pequeñas y medianas empresas mexicanas para el cumplimiento de la Agenda 2030 a través de la cooperación internacional: el caso español “Pymes y ODS”
Authors: Magos Chávez Ricardo , Pérez Pineda Jorge Antonio
Published: June 2022

La participación del sector privado se ha vuelto cada vez más relevante en el contexto internacional. Diversas iniciativas y agencias de cooperación dan muestra de esta importancia al incluirles en sus programas o estrategias, tales como el Pacto Mundial de Naciones Unidas, o recientemente, dentro de la Alianza Global para Cooperación Eficaz al Desarrollo. En tal sentido, en el contexto actual, es necesario conocer cómo, particularmente las Micro, Pequeñas y Medianas Empresas (MIPYMES), pueden contribuir al cumplimiento de la Agenda 2030. Así el presente estudio, analiza una serie de factores relevantes para esta inclusión, a partir del análisis del proyecto español “PYMES y ODS”, esperando con ello, dar insumos que sirvan a la cooperación mexicana para la inclusión de las MIPYMES en la cooperación que realiza la Agencia Mexicana de Cooperación Internacional para el Desarrollo (AMEXCID).
Gestión social empresarial: análisis de efectos marginales para el mejoramiento reputacional
Authors: Guerrero Pájaro Alejandro , Barraza Pava Milagro Elena
Published: June 2022

La gestión social corporativa se ha convertido en el derrotero del relacionamiento entre comunidad y empresa, por medio de este se pueden alcanzar resultados positivos de manera recíproca, partiendo de las realidades de las comunidades evaluadas a partir del levantamiento de líneas base, caracterizaciones, entre otras, que permiten un reconocimiento del entorno donde se ejecutan los diferentes proyectos que responden a las líneas de inversión de las empresas. Partiendo de la premisa de que las comunidades participan de dichos proyectos para mejorar las condiciones territoriales, se logra crear un ecosistema que se centra en el mutualismo y evita el comensalismo, socialmente hablando. A partir de la implementación de un modelo Probit se logró evidenciar estadísticamente la correlación existente entre la percepción de la gestión social frente a los proyectos que ejecutan las empresas, que generan mayor impacto y son aceptables de acuerdo con sus entornos socioeconómicos y culturales.
Palabras clave: gestión social; desarrollo sostenible; proyectos de desarrollo; comunidad; afrodescendientes.
Mecanismos de participación y gobernanza de Colombia y Chile
Authors: Benito Revollo Ariana Lucía
Published: June 2022

En la última década Colombia y Chile han vivido una transformación permanente hacia un enfoque descentralizador, uno y otro, buscando la mejor estructura, intentándose alejar de aquellos centralismos arraigados en el caso de Chile, y en el de Colombia un constante cambio que conlleve a la mejora de las transferencias de recursos a los municipios más alejados, en un escenario que es complejo, como es el del conflicto armado interno.
El objetivo de la investigación es analizar, a través de los mecanismos de participación ciudadana existentes en uno y otro país, para el caso de Colombia y Chile, perfeccionar los sistemas de gobernanza subnacional. Lo que a la postre tiene notorias repercusiones en la distribución de funciones, recursos y competencias que mejoren la calidad de vida de los ciudadanos y de sus respectivos territorios. Este artículo parte de una revisión de datos bibliográficos y documentales en cuanto al estudio y observancia del funcionamiento del Estado, bajo la necesidad idealizante de ser agente de desarrollo económico y social, en un escenario creciente de demandas por parte de la sociedad civil, solicitante de una mayor autonomía regional y mayor participación de dichas decisiones en el plano local. Lo actual, nos ubica en un pacto social, haciéndose necesario que se produzcan cambios de carácter alternativo para los países, intentando superar la deficiente calidad de la gestión pública y la irracionalidad en el uso de los recursos, por parte de las administraciones locales.
Palabras clave: modernización; gobernanza; Colombia; Chile; participación; regulación; políticas públicas.
Lo preocupante en el caso de Colombia, es la desconfianza presente en el Estado y en su necesidad idealizante de ser agente de desarrollo económico y social, a contrario sensu, lo que ha creado y motivado, es un escenario creciente de demandas por parte de la sociedad civil, solicitante de una mayor autonomía regional y mayor participación de dichas decisiones en el plano local. Lo actual, nos visiona en una desnaturalización de ese pacto social, el cual ha perdido todo sustento, haciéndose necesario que se produzcan cambios de carácter alternativo para el país, intentando superar la deficiente calidad de la gestión pública y la irracionalidad en el uso de los recursos, por parte de las administraciones locales
La Unión Europea y la construcción de la agenda de género africana en el marco de la Cooperación Internacional al Desarrollo
Authors: Morasso Carla
Published: June 2022

La igualdad de género ocupa actualmente un lugar central en las estrategias de Ayuda Oficial al Desarrollo. Los oferentes de cooperación internacional consideran que disminuir la brecha de género es un factor clave para el desarrollo sostenible. Entre ellos se distingue la Unión Europea, la cual, a partir de su rol de normative power, se constituyó como un actor central en el impulso de las agendas de género a través de sus relaciones exteriores. Esto puede observarse en el caso de África, un socio privilegiado europeo donde se han desplegado numerosos programas y proyectos orientados principalmente a disminuir el gap de género y empoderar económicamente a las mujeres. En este contexto, el artículo aborda el rol que ha tenido la cooperación europea en la difusión de valores y prácticas de género en el continente africano, dando cuenta de las principales iniciativas ejecutadas y brindando algunas reflexiones sobre los resultados alcanzados.     
Palabras clave: Género – Unión Europea – África – Poder Normativo – Cooperación Internacional al Desarrollo
Dossier: Sector Privado, Cooperación Internacional y Desarrollo en América Latina
Authors: Pérez-Pineda Jorge A. , Blanco-Rangel Ibelis
Published: June 2022

En la actualidad, la Agenda 2030 se ha convertido en el referente de la comunidad internacional en la búsqueda de un mundo más sostenible, con mayor desarrollo y con menor pobreza. Dicha agenda se reconoce como universal, multinivel y multiactor, buscando abarcar en la medida de lo posible, no solo los temas más sensibles en torno al desarrollo, sino a todos los actores clave que, directa o indirectamente, inciden en este. En dicho contexto, es el sector privado uno de los actores que en los últimos años aparece como “novedoso”. Ello se debe a que, desde otras agendas internacionales, como la de la “Eficacia de la ayuda y desarrollo”, de la “Financiación al Desarrollo” o la de “Derechos Humanos”, se ha observado un gradual involucramiento del sector privado, ya no solo como financiador, sino también como socio de acciones para el desarrollo desde hace más de una década.
Elements and Stages of Regional Financial Strategies Development
Authors: Alimuradov Murad
Published: June 2022

Choosing the appropriate elements and stages of a regional financial strategy is an important scientific and methodological task. According to the theory of strategy and the methodology of strategizing, this aspect is also important for regional financial systems. In the context of limited resources and intense inter-regional competition, a regional financial strategy should be consistent with higher-level strategies and attract financial resources to implement the local strategic priorities. The theory of strategy and strategizing methodology developed by Professor V.L. Kvint can be applied to regional financial strategies. The article features philosophical foundations of the strategy: values, elements, stages, stakeholders, and their relationship in the process of regional financial strategizing.