bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship of paraoxonase-1 and paraoxonase-3 with routine laboratory tests and oxidative stress in type 2 diabetes mellitus
Authors: Ucar Yagcı Yagmur , Yılmaz Bulbul Buket , Sut Necdet , Ozgun Eray
Published: September 2024

Objectives

We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes mellitus (T2DM). Also, we aimed to examine PON1 and PON3 levels and activities in these patients according to the HbA1c goal in diabetes treatment and PON1192 phenotypes.

Methods

One hundred forty-one volunteers diagnosed with T2DM participated in this study. Serum PON1 and PON3 levels and activities, total oxidant status (TOS), and total antioxidant status (TAS) were measured. PON1192 phenotypes were determined by using PON1 activities. Also, HbA1c, serum fasting blood glucose, and lipid profile results, which were measured for routine examination on the same day as sample collection, were used for this study.

Results

There was a positive relationship between arylesterase and lactonase activities and high-density lipoprotein cholesterol (HDL-C), between lactonase activity and TAS, and a negative relationship between PON1 level and TAS in patients with T2DM. Our study also showed that PON3/HDL-C was higher in patients with HbA1c levels ≥7 %. Lactonase activities were higher in patients with PON1Q192Q and PON1Q192R phenotypes than in patients with PON1R192R phenotypes.

Conclusions

PON1 and PON3 levels and activities alone could not be associated with immediate or long-term blood glucose levels in patients with T2DM. Higher PON3/HDL-C in patients with HbA1c levels ≥7 % may show a protective role of PON3 in defense against higher glucose levels. Also, we found that the PON1192 phenotype can affect serum lactonase activity.
1-Nitronaphthalene, a non-OD, non-MDO polytype
Authors: Schöbinger Matthias , Stöger Berthold
Published: September 2024

Crystals of 1-nitronaphthalene were grown by evaporation of a methanol solution. The structure [P21/c, a = 13.2780(13) Å, b = 3.8131(3)° Å, c = 31.851(3) Å, β = 91.173(8), V = 1,612.3 Å3] was solved from a crystal twinned by twofold rotation about [100]. Twinning is explained by the polytype character: layers with (idealized) p2111 symmetry can connect via either 1‾ or 21 operations, leading to geometrically distinct pairs of layers. In the twin individuals, the two kinds of contacts alternate, at the composition plane two subsequent contacts of the same type are realized.
Synthesis and crystal structure of a tripeptide comprising a centrally placed non-coded aromatic γ-amino acid
Authors: Das Purak , Das Suven , Dutta Arpita
Published: September 2024

A protected tripeptide Boc-l-Leu-5-AIA-Aib-OMe was synthesized where 5-aminoisophthalic acid (5-AIA), a rigid non-coded aromatic γ-amino acid is incorporated as central residue. The single crystal X-ray diffraction study indicates that the peptide self-assembles into supramolecular sheet through intermolecular hydrogen bonding interaction N–H⋯O and π
···
π interaction.
O ensaio como irresolução. Contemporaneidades de Eduardo Lourenço
Authors: Monteiro Hugo
Published: September 2024

Marcado desde sempre pela relação entre filosofia e literatura, o pensamento de Eduardo Lourenço (1923-2020) desenvolve-se ao longo de uma vasta produção intelectual – parte ainda inédita – correspondente a uma profunda, atenta e responsável atenção ao seu tempo. Este artigo parte dessa atenção, intentando demonstrar os contornos da sua originalidade, bem como mapear os traços principais do seu relevo filosófico-literário. Passando pelas noções de “heterodoxia”, de “ensaísmo” e de “temporalidade”, pretende-se acompanhar algumas vias percorridas pela obra do pensador, esclarecendo o modo como se constroem a partir de um alargamento da ideia de razão alimentada pela multiplicidade dos desafios do tempo.
Heredada, comprada, regalada: la biblioteca ‘propia’ de Emilia Pardo Bazán
Authors: Agra Romero María Xosé , Varela Orol Concha
Published: September 2024

El objeto de este trabajo es identificar y analizar los distintos estratos perceptibles hoy en la biblioteca de Emilia Pardo Bazán, especialmente la colección de libros pertenecientes a su padre José Pardo Bazán, así como el alto número de autoras y sus obras presentes en los fondos. Ambas secciones constituyen dos de las grandes aportaciones de la biblioteca al patrimonio bibliográfico y a la historia de Galicia, así como a la historia de las mujeres y el feminismo. Se concluye indicando la necesidad de acometer medidas necesarias y urgentes (unificación espacial de los fondos, buena conservación, mejoras en su catalogación) para que este valioso patrimonio sea de fácil acceso, más y mejor conocido, tanto para la ciudadanía como para la comunidad de investigadoras e investigadores.
El decir veraz y la práctica pedagógica universitaria de cara al ejercicio de la libertad
Authors: Escobar Galo Juan Pablo
Published: September 2024

This essay intends to think about the professional education offered by the university in its search for truth as an experience related to reality and the exercise of freedom. It thus analyzes pedagogical discourse in superior education. It also describes how actions can be taken to foster a coherent professional instruction that seeks to transform local and global reality. The essay concludes that, in order to attain an emancipating, critical professional education, it is crucial to modify traditional pedagogical discourse, to educate in parresia (truthful discourse), and to develop alternative educational models, all of which implies significant changes in university institutions, so that these become able to modify learning and teaching processes in the classroom.
EXTRACTION OF SULPHUR-CONTAINING AND POLYCYCLIC AROMATIC COMPOUNDS OF DIESEL FUEL WITH IMIDAZOLE-CONTAINING IONIC LIQUIDS
Authors: КОБОТАЕВА Н.С. , САВИНЫХ Ю.В. , СКОРОХОДОВА Т.С.
Published: September 2024

Проведено исследование процесса экстракции серосодержащих соединений дизельного топлива (ДТ) ионными жидкостями (ИЖ) на основе имидазола с различными заместителями (бутил, октил, нонил, додецил, цетил) в положении 1 имидазольного кольца и определен состав серосодержащих соединений и полициклических ароматических углеводородов (ПАУ) методом хромато-масс-спектрометрии в исходном и очищенном ДТ. Определены оптимальные условия процесса экстракции: температура 30-35 °С, время экстракции 60 мин, соотношение ДТ/ИЖ = 1.66-2. Наиболее эффективным в качестве экстрагента серосодержащих соединений ДТ является 1-нонил-3-метилимидазолия бромид, позволяющий снизить общее содержание серы с 0.369 до 0.143 мас. %. Результаты исследования группового и индивидуального состава производных дибензотиофена (ДБТ) и ПАУ показали, что степень извлечения производных ДБТ и трициклических ароматических углеводородов составляет 66-72 %. В меньшей степени происходит извлечение нафталина и его гомологов - 37 %. Среди гомологов ДБТ наиболее полно извлекается диметилдибензотиофен.

The extraction of sulphur-containing compounds of diesel fuel (DF) with ionic liquids (IL) based on imidazole with various substituents (butyl, octyl, nonyl, dodecyl, cetyl) in position 1 of the imidazole ring has been studied; the composition of sulphur-containing compounds and polycyclic aromatic hydrocarbons (PAH) has been determined by gas chromatography - mass spectrometry in the initial and purified diesel fuel. The optimal extraction conditions are determined: temperature 30-35 °C, extraction time 60 min, DF/IL ratio 1.66-2. The most effective extractant for the sulphur-containing compounds of DF is 1-nonyl-3-methylimidazolium bromide, which allows reducing the total sulphur content from 0.369 to 0.143 wt%. Results of the studies of group and individual composition of dibenzothiophene (DBT) and PAH derivatives show that the degree of extraction of DBT derivatives and tricyclic aromatic hydrocarbons is 66-72%. Naphthalene and its homologues are extracted to a lesser extent - 37%. Among DBT homologues, dimethyldibenzothiophene is extracted most completely.
El español loretano en Leticia: ideologías lingüísticas y racialización en la frontera
Authors: Chinellato Díaz Alessio
Published: September 2024

La negociación identitaria, las prácticas lingüísticas y las formas de concebir los recursos comunicativos en zonas fronterizas como la que comparten Perú, Brasil y Colombia en el Amazonas dependen, en gran medida, de diferencias socioculturales organizadas por largos y conflictivos procesos de colonización, fronterización y nacionalización. Considerando esta premisa, el presente artículo se enfoca en la construcción ideológica de diferencias sociolingüísticas, particularmente, en la construcción del “español loretano” (del departamento de Loreto, Perú) por parte de habitantes colombianos/as de la ciudad fronteriza de Leticia (Colombia). A partir de un corpus de datos sociolingüístico-etnográficos recabados en los años 2018 y 2020, se analizaron fragmentos discursivos extraídos de entrevistas semiestructuradas realizadas en esta localidad, mostrando cómo la percepción del español loretano hace parte de un contraste ideológico entre categorías sociales y lingüísticas, que halla expresión en discursos locales que reproducen estereotipos negativos y formas de parodia lingüística, impulsando la racialización y la marginación de la población peruana amazónica. Estos hallazgos permiten poner de relieve el papel del lenguaje en los procesos de racialización, así como conectar la construcción lingüístico-ideológica de identidades etno-raciales con la pervivencia de lógicas coloniales e intereses políticos y económicos vinculados al proyecto de nacionalización de los Estados que confluyen en esta zona de frontera.
Lengua y Sociedad. (2023). Revista del Instituto de Investigación y Lingüística Aplicada (CILA) de la Facultad de Letras y Ciencias Humanas. Volumen 22, n.° 2, diciembre, 703 pp.
Authors: Saravia Durand Sonia Nicol
Published: September 2024

El segundo número del volumen veintidós de la revista Lengua y Sociedad, que presenta el periodo de junio-diciembre de 2023, alberga veintiocho artículos académicos de diferentes temáticas. Las áreas de especialidad abordadas por los autores tratan sobre el análisis crítico del discurso, la semántica cognitiva, la sociolingüística, la glotopolítica, la pragmática, la sintaxis y la enseñanza de lenguas. Asimismo, se presentan artículos vinculados a la lingüística histórica y el contacto lingüístico.
Dirección Nacional de Educación Básica Especial. (2006). Perú Mama Makillawan Rimaykuna. Manual de Lenguaje de Señas Peruanas
Authors: Catalán Yedirel , Sanchez Diana
Published: September 2024

Es visible la situación de diglosia en la que se encuentran las lenguas de señas con respecto a las lenguas orales (Karnopp, 2004): se trata de un sistema de una minoría lingüística (Lane, 1992; Pérez de la Fuente, 2014), por lo que requiere que se consideren medidas a fin de que su uso trascienda el ámbito familiar, al que se ha visto restringida, y así logre el estatus de lenguas dominantes como el español (Karnopp, 2004). La elaboración de materiales como diccionarios de lengua de señas podría favorecer tanto a su aprendizaje como a su difusión (Instituto Nacional para Sordos, Instituto Caro y Cuervo y Educación de calidad, 2011).
Missionary work of Mariae Vitae Congregation
Authors: Keidošiūtė Elena
Published: September 2024

The research of Jewish conversions and their concepts in Vilnius city and Vilnius bishopric is aimed at the activity of congregation Mariae Vitae (1737-1864) - unique both in Lithuania and in Europe at large. According to the rule of Mariae Vitae Congregation, it had to deal with religious and lay education of converted girls (mainly Jewish) and provide them with practical skills of work so they could establish in Catholic society. The innovatory social program of Mariae Vitae Congregation, including education and financial help, answered to possible problems of neophytes in Poland and Lithuania of the 18th-19th centuries.
There was no institution dedicated to the care of Jewish catechumens and Mariae Vitae Congregation filled that gap, relieving the integration to Catholic society. The Jews themselves opposed this practice and tried to regain lost members of the community, but these attempts could be successful only if a neophyte was already an adult and showed a will to come back. Besides honest will to baptize, widowhood, potential marriage with a Catholic, and financial problems could be very real spurs to turn to Mariae Vitae sisters.
Bilateral lumbosacral plexopathy: A rare condition presenting as a diagnostic challenge
Authors: Almeida Gabi , Soares Ivone , Cruz Cristina , Pinto Joana , Ribeiro Sofia , Pereira Patrícia , Cunha Mafalda , Melo Bruna
Published: September 2024

Lumbosacral plexopathy (LP) is an uncommon condition. Its diagnosis may be challenging especially in the absence of evident structural causes and should be supported by lumbosacral imaging and neurophysiologic studies. LP is considered idiopathic when no causal factor is identified and it is thought to be immune-mediated. The authors report the case of a male with priors of radical prostatectomy and pelvic radiotherapy who presented the nosological triad of LP: lower limb progressive muscle weakness, sensory disturbances, and pain. Extensive investigation excluded different etiologies but no undoubtful causal conclusions were reached, raising the exclusion diagnosis of idiopathic LP as most likely. The patient was started on a rehabilitation program and several therapies, including corticotherapy, tocopherol, pentoxifylline, and hyperbaric oxygen therapy (the latter three targeting a less likely hypothesis of post-radiation LP), showing progressive improvement. Early intervention by a multidisciplinary team may have facilitated this favorable outcome. Despite all questions, the authors hope this report alerts to this rare entity.
Antifungal, Hydrolytic Enzyme Activity, and Identification of Gut Bacterial in Feces of Black Soldier Fly (Hermetia illucens) Larvae
Authors: Maulida Meirina Nur , Fatmawati Umi
Published: September 2024

AbstractBlack soldier fly (BSF) (Hermetia illucens) is a type of fly that has larvae called maggots with potential as a waste bioremediation agent. Maggot from BSF has unique digestive characteristics with a diversity of bacteria in it which helps maggot digest organic materials by producing various hydrolytic enzymes. Fecal bacteria in maggots also have potential antifungal activity. This research aimed to identify the hydrolytic and antifungal enzyme activity of maggot fecal bacteria (Hermetia illucencs). Hydrolytic enzyme activity is carried out by measuring the hydrolytic zone in the test medium. The antifungal antagonist test was carried out on Phytophthora sp. using the dual agar culture method. The results of the enzyme activity test showed that isolate MNM 001 had proteolytic enzyme activity, MNM 002 had amylolytic, and proteolytic enzyme activity, and was able to dissolve P elements. MNM 003 had cellulolytic, amylolytic, and proteolytic enzyme activity. From the results of the antagonist test, MNM 001, MNM 002, and MNM 003 have antifungal activity against Phytophthora sp. of the three isolates, isolates MNM 002 and MNM 003 had the best hydrolytic enzyme activity and were identified using the 16S rRNA gene. The results of amplification of the 16S rRNA gene from MNM 002 and MNM 003 indicated that the two isolates were close to the genus Brevibacterium.AbstrakBlack soldier fly (BSF) (Hermetia illucens) adalah jenis lalat yang memiliki larva disebut maggot dengan potensi sebagai agen bioremediasi sampah. Maggot dari BSF memiliki karakterisitik pencernaan unik dengan keragaman bakteri di dalamnya yang membantu maggot mencerna bahan organik dengan menghasilkan beragam enzim hidrolitik. Bakteri pada feses maggot juga memiliki potensi aktivitas antifungi. Tujuan dari penelitian ini adalah untuk mengidentifikasi aktivitas enzim hidrolitik dan antifungi dari bakteri feses maggot (Hermetia illucens). Aktivitas enzim hidrolitik dilakukan dengan mengukur zona hidrolitik pada medium uji. Uji antagonis antifungi dilakukan terhadap Phytophthora sp. dengan metode dual culture agar. Hasil uji aktivitas enzyme menunjukkan isolat MNM 001 memiliki aktivitas enzim proteolitik, MNM 002 memiliki aktivitas enzim amilolitik, proteolitik, dan mampu melarutkan unsur P. MNM 003 memiliki aktivitas enzim selulolitik, amilolitik, dan proteolitik. Hasil uji antagonis MNM 001, MNM 002, dan MNM 003 memiliki aktivitas antifungi terhadap Phytophthora sp. Ketiga isolat tersebut, isolate MNM 001, MNM 002, dan MNM 003 memiliki aktivitas enzim hidrolitik terbaik dan diidentifikasi menggunakan gen 16S rRNA. Hasil amplifikasi gen 16S rRNA dari MNM 002 dan MNM 003 mengindikasikan bahwa kedua isolat tersebut memiliki kedekatan dengan genus Brevibacterium.
The war in Ukraine in light of international law
Authors: Lamm Vanda
Published: September 2024

The aggression and the ‘special military operation’ against Ukraine by the Russian Federation have, since their outset, implied not only the violation of fundamental customary and treaty norms of international law, but, at the same time also undermine the foundations of the contemporary international legal order. The ‘special military operation’ violates several universal international conventions in the elaboration of which the predecessor state of contemporary Russia, the Soviet Union had a definitive role; furthermore, it expressly breaches Russian undertakings concerning respect for the independence and sovereignty of Ukraine. Since in this case the aggressor state is a permanent member of the UN Security Council, thus, instead of the Council, the emergency special session of the UN General Assembly proceeds on the basis of the Uniting for Peace resolution and makes recommendations for collective measures to the Member States. The present study discusses the most important international norms breached with the aggression and during the war, the resolutions of the emergency special sessions of the UN General Assembly, the post-war situation, as well as the issue of remedy and reparation due to Ukraine.
Myelomás beteg 11 éves remissziót ért el másodvonalban adott lenalidomiddal – esetismertetés
Authors: Földeák Dóra Melinda , Borbényi Zita , Modok Szabolcs
Published: September 2024

A myeloma multiplex egy rosszindulatú vérképzőszervi daganatos betegség, melynek kórlefolyását remissziók és relapszusok jellemzik. Egy betegünk kórtörténetét mutatjuk be, aki 5 évig kapott – klinikai vizsgálatban – másodvonalban lenalidomide + dexamethason kezelést és összesen 11 évig remisszióban volt. A beteg egy – szövettanilag nem verifikált – tüdődaganatban hunyt el, melynek kialakulásában inkább az erős dohányzás, kevésbé a tartós lenalidomide-kezelés játszhatott szerepet.
Field-assisted sintering of refractory oxygen-ion and proton conducting ceramics
Authors:   Institute of High Temperature Electrochemistry of the Ural Branch of the Russian Academy of Sciences, Dunyushkina Liliya A.
Published: September 2024

Solid oxides with high oxygen-ion and proton conductivity have been extensively studied for applications in electrochemical devices such as fuel cells, electrolyzers, sensors, hydrogen separators, etc. However, the preparation of high-density ceramic electrolytes is often complicated by the exceptional refractoriness of most oxygen-ion conducting solid oxide phases. Therefore, conventional sintering of these materials is very energy consuming and low effective. In recent years, non-conventional field-assisted sintering technologies (FASTs) such as spark plasma sintering, flash sintering and microwave sintering, have been developed and applied for sintering dense ceramic electrolytes at reduced temperatures. In this article, the applications of FASTs for densification of refractory oxygen-ion and proton conducting ceramics are reviewed, while the mechanisms, advantages and limitations of these technologies are discussed, with special emphasis on the effects of FASTs on the microstructural and transport properties of sintered materials, and the performance of FAST-processed electrochemical cells.
Reconstruction of Photographic Images in the Novel Sixty Lights by Gail Jones
Authors:   Ural Federal University, Sidorova Olga G. , Poluektova Tatiana A. ,   Krasnoyarsk State Pedagogical University named after V. P. Astafiev
Published: September 2024

The article is devoted to the analysis of the neo­Victorian novel “Sixty Lights” (2004) by the modern Australian writer Gail Jones. The purpose of the study is to identify the role of photographic images presented in the form of photographic ekphrasis and further substantiate the genre status of the novel. The plot centers on the history of the formation and development of photography in the second half of the XIXth century, the history intertwined with the life of the main character, Lucy Strange, who became a professional photographer. With the help of photography, or “writing of light” (Jean Baudrillard), the world is learned and meaning is brought into it: by reconstructing images of reality through vision and photography (from royalty and family members to everyday objects), Lucy creates documents of the era, documents of memory, intended to be “read” by future generations. In Victorian Britain, photography became one of the brightest sociocultural symbols of the era, embodying such concepts as memory, death, identity, etc. The use of the methodology of historical, literary and intermedial analysis made it possible for the authors to identify the genre­forming potential of photographic ekphrasis and, on this basis, define the genre modification of the novel “Sixty Lights” by G. Jones as photo­ekphrastic, and its kind as a photo­reconstruction novel.
Pulmonary hypertension in ischemic heart failure: a pilot study
Authors: Mareyeva V. A. , Bogdanova A. A. , Nikiforova Т. A. , Klimenko A. A.
Published: September 2024

Aim. To evaluate the role of cardiopulmonary system assessment in a group of patients with pulmonary hypertension (PH) associated with ischemic heart failure (HF) with the right ventricular-pulmonary arterial (RV-PA) coupling.

Material and methods. Forty stable patients were examined. The patients were divided into 3 groups depending on the left ventricle ejection fraction (LVEF). PH was established by using expert transthoracic echocardiography. RV-PA coupling was calculated by 2 following ways: as tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (PASP) ratio and as TAPSE´Pulmonary Artery Aceleration Time (pACT) multiplication.

Results. The patients included in the study were mainly men (73,8%), functional class PH II-III (95,2%), stage IIB CHF (62%). The highest values of TAPSE (18,6±3 mm) and RV-PA coupling (0,64±0,42 mm/mm Hg) were found in the patients with preserved LVEF. In the general cohort, high level of NT-proBNP corresponds to reduced values of RVPA coupling (rs=-0,563) and TAPSE (rs=-0,666; p<0,01). The severity of PH directly affects the level of NT-proBNP (p<0,01). As the stage of HF and PH functional class increases, the indicators of PASP, inferior vena cava diameter and NT-proBNP level significantly increase, as well as TAPSE and RV-PA coupling decrease (p<0,05). Different calculating methods of RV-PA coupling has a strong correlation (rs=0,832; p<0,01).

Conclusion. The right heart and RV-PA coupling assessment in patients with ischemic HF of origin is of significant value for the early diagnosis of PH and timely clinical decision-making.
Mammographic breast density and cardiovascular disease in women. A literature review
Authors: Bochkareva E. V. , Rozhkova N. I. , Butina E. K E. K. , Kim I. V. , Molchanova O. V. , Mikushin S. Yu. , Ipatov P. V. , Drapkina O. M.
Published: September 2024

The world is searching for new simple and economically available gender-specific markers to improve cardiovascular risk stratification in women. The aim of this review was to analyze the association of mammographic density (MD) with cardiovascular disease (CVD). In low MD, i.e., high relative mammary gland fat content, there is a higher incidence of the main risk factors for CVD: hypertension, hyperlipidemia, hyperglycemia, excess body weight, as well as an increase in the volume of fat depots, visceral and ectopic fat. Low MD is associated with a higher 10-year risk of adverse cardiovascular events such as coronary artery disease, stroke, peripheral arterial disease, revascularization, and heart failure, and may serve as a predictor of their development. Including MD in the Framingham Risk Score model improves its accuracy. Identification of low MD, as a marker of high cardiovascular risk, allows the use of mammography for early detection and prevention of the two most dangerous diseases among the female population — breast cancer and CVD.
DESIGN OF A LOW-POWER HIGH-SPEED TRUE SINGLE-PHASE CLOCK D FLIP-FLOP FOR VERNIER TIME-TO-DIGITAL CONVERTERS
Authors: Kesanasetty Leela Sravani , Vijaya Lakshmi Posani , Valluri Aswini
Published: September 2024

Modern very large-scale integration technology is primarily driven by digital circuits since they have
several advantages over analog circuits. Compact and simple circuits can be used to perform ultrafast
digital operations. One of the essential elements of Bluetooth, global system for mobile communications,
and Wi-Fi applications is an all-digital phase-locked loop (ADPLL). Furthermore, a vital part of
the ADPLL is the Vernier time-to-digital converter (TDC). Vernier TDC output is typically produced
using D flip-flop circuits. Therefore, by employing Virtuoso generic process design kit 180-nm technology
on the Cadence platform, we designed a high-speed low-power positive edge-triggered true single-phase
clock (TSPC) D flip-flop circuit for Vernier TDCs.
Integrative Review of Riparian Buffers Benefits in Urbanized Watersheds
Authors: Denning Paige , Schulte Scott
Published: September 2024

Riparian buffers or riparian corridors are areas of vegetation in the floodplains and areas surrounding a stream. By the early 2000s, numerous national reports and studies of riparian buffer benefits established that vegetation near streams is helpful in protecting the stream from increasing urban runoff, minimizing bank erosion, reducing flooding, and improving overall water quality. However, influential studies concluded that buffer benefits dwindle as urbanization increases, eventually becoming ineffective. This study evaluates more recent research that suggests riparian buffers are more effective at countering urbanization impacts than previously understood, and considers the extent to which we can quantify these benefits and identify the factors that maximize their effectiveness (i.e. greater efficiency based on buffer distance from the stream, extent of stream setbacks, and percentage of impervious cover in the area). Much of the research has been conducted in the Kansas City area in the Blue River Watershed, which begins in Kansas and flows into Missouri River east of downtown Kansas City, Missouri. About 800,000 residents live in the watershed, which includes some of the region’s fastest growing areas. It is critical to protect this major resource, and other regional rivers and streams, for residents of the Kansas City Metropolitan area and the ecosystems that depend on them. It is also critical to provide the latest and best information to the community-of-practice currently updating regional stormwater management planning and design guidance.
Pornography Consumption and Sexual Behaviors in Spanish Adolescents and Young Adults: Findings from a Sample of Girls and Boys Aged 15 to 29 Years
Authors: Díaz Hernández Cristian , Gutiérrez Barroso Josué , Torrado Martín-Palomino Esther
Published: September 2024

In recent years, there has been an increase in the consumption of pornography, particularly among young people and adolescents, with implications that are beginning to be more thoroughly examined in Spain. Therefore, the objective of this research is to understand the relationship between the consumption of pornography in Spanish adolescents and young men and women and its repercussions on their sexual behaviors. The sample was drawn from the study published in 2020 by the Youth Institute of the Spanish Government, comprising a total of 4,562 individuals aged between 15 and 29. The results indicate that, in most cases, when they started having sex, men had already consumed pornography several times a week, while women did not or had done so only once in their lifetime. Both women and men who had done things they did not want to do in their sexual relationships consumed more pornography than those who had not done things they did not want to do. Men and women who consume more pornography tend to refrain from using condoms because they feel the sexual encounter more, although the trend is not very clear. The study concludes on the significance of pornography as a socializing and educational element among young men and women.
Reasons of Requests for Psychological Help in an Emergency Hospital
Authors: Rakhmanina A.A. , Gamzatova A.S. , Tseitlina M.D. , Koroleva A.V.
Published: September 2024

Psychological assistance to patients in an emergency multidisciplinary hospital is increasingly relevant due to the influence of mental disorders and emotional maladjustment on treatment, the patient’s internal perception of their illness, and adherence to treatment. Since hospitalization is inherently a stressful factor that can contribute to the development of anxiety and depressive symptoms, psychological support for patients and often their loved ones is an integral part of the treatment process. However, studies on the emotional state of patients at the time of hospitalization are limited and primarily focus on assessing the level of current stress. Patients admitted to the hospital often experience symptoms of emotional maladjustment long before hospitalization, which can significantly impact their adaptation to the hospital environment and the treatment process as a whole. This article analyzes the reasons for seeking psychological help during hospitalization in an emergency hospital and examines the relationship between these reasons and the level of emotional maladjustment. The analysis of primary issues was conducted by coding each case according to the most prominent problem presented. A total of 379 consultations were analyzed, identifying problems associated with psychological distress. The sample consisted of 122 men and 257 women, with an average age of 50 years. Also, some patients completed the Hospital Anxiety and Depression Scale (HADS), including 30 men and 50 women. The results of the study showed that one of the most common reasons for seeking psychological help was related to situational reactions to stress. However, the majority of patients in this group did not have elevated scores on the Hospital Anxiety and Depression Scale. In addition, a significant percentage (37% of all consultations) of patients were referred for psychological consultation due to emotional problems that had been present before hospitalization. Notably, patients in this group were most often among those with clinically significant levels of anxiety and depression. The data obtained may indicate that the main reason for the deterioration of the emotional state at the time of hospitalization is not hospitalization itself, but problems that the patient has encountered outside the hospital walls.
Internet Gaming Disorder and Unmet Psychological Needs: Mediating Roles of Self-Esteem, Depression, and Escapism
Authors: Gedik Z. , Gulec M.
Published: September 2024

Internet gaming disorder (IGD) is a widespread mental health issue especially among youth but its etiology remains unclear. The aim of this study was to test an integrative path model in which basic universal psychological needs of competence, autonomy, and relatedness predict IGD through the serial mediation of self-esteem, depression, and escape motivation. Study design was cross-sectional. A total of 331 Turkish gamers whose mean age was 22.7 years (SD=4.73) were recruited through purposive sampling. Among the participants, 57.1% (n=189) were male and 42.9% (n=142) were female. Online standardized self-report questionnaires for measuring IGD, gaming motivations, basic psychological needs satisfaction, self-esteem, and depression were filled out by the participants. In this regard, a personal information form, the Internet Gaming Disorder Scale-Short Form, Motives for Online Gaming Questionnaire, Basic Psychological Need Satisfaction Scale-In General, Rosenberg Self-Esteem Scale, and the Hospital Anxiety Depression Scale-Depression Subscale were administered. Men had higher mean IGD and gaming motivations scores compared to women. It was found that self-esteem, depression, and escapism serially mediated the association between basic psychological needs and IGD. The contribution of the findings to the relevant literature and clinical implications were discussed.
Thinking-language Disorders Types’ of Schizophrenia Spectrum Disorders Patients
Authors: Smerchinskaya E.M. , Tregubenko I.A. , Isaeva E.R.
Published: September 2024

In the study of schizophrenia, special attention is paid to speech disorders. However, the descriptions of linguistic component are usually phenomenological. An objective structure analysis of language is needed, which could be useful to identify additional markers in assessing mental state and clarify criteria for differential psychodiagnostic. The possibility of adapting existing English-language studies is ambiguous, and a method based on the Russian-language sample is required. The study is aimed to identify types of speech characteristics in patients with schizophrenic spectrum disorders related to patopsychological thinking characteristics. The sample consisted of 70 people: 45 schizophrenia patients, 25 conditionally healthy participants. Methods used: expert assessment, experimental methods (tests of thinking, analysis of speech production), content-analysis, statistical analysis. Schizophrenia patients’ oral and written speech consist of less words, descriptions of feelings and thoughts than healthy participants. Schizophrenia patients’ speech is grammatically simpler, more formal, more inclusive, low communicative than healthy participants speech. Three types of written speech were found in patients with schizophrenia: Peculiar description of internal experiences, Narrative poverty, Reference to “I”. Two types of oral speech were also found: Narrative poverty, "Philosophizing". All types of written speech and Philosophizing in oral speech were significantly related to thinking disorders. The 5 speech characteristics that form in connection with thinking disorders characteristic of schizophrenia result in 3 types of speech-thinking disorders.
Features of the Relationship between Cardiorhythm Regulation and Components of Internal Picture of Disease in Students
Authors: Elnikova O.E. , Dobrin A.V.
Published: September 2024

The work is aimed at identifying the features of the mechanisms of regulation of cardiac rhythm, which determine adaptive behavior in situations of health disorders. Materials from two empirical studies conducted on a sample of 1st to 4th year students at Yelets University are presented. The study 1 (N=160) involved respondents aged 17 to 23 years of both sexes, of whom 37.5% had various health problems. In study 2 (N=60), students (average age 21±2.3 years), of which 50% belong to the category of chronically ill, 50% had periodic health problems. Study 2 included five stages, in which four levels of the internal picture of the disease (IPD) were diagnosed and cardiac rhythm measurements were performed at rest and against the background of existing disease memories. The following methods were used: SF-36 Health Status Survey, Health, Activity, and Mood questionnaire, SCL-90-R, “Coping behavior in stressful situations”, “Level of subjective control”, TATD method. The fixation of the heart rate variability was carried out using the hardware and software complex OMEGA-M. The results obtained allow us to say that there is a correlation between the individual components of IPD and the parameters of regulation of heart rate variability. The optimal state of the body's homeostatic systems, which ensure successful adaptation, is characterized by the activity of the parasympathetic department of autonomic nervous system in the process of cardioregulation.
The Russian Federation as a subject of financial law
Authors: Gorlova E. N.
Published: September 2024

The key characteristics of the legal status of public legal entities as subjects of financial law are publicity, authority, sovereignty, as well as the financial basis. Within the framework of financial activity, the unity of the system of public power and federally determined separation of powers between levels of government are combined. In this regard, it is especially important to determine the legal personality of public legal entities in financial law. Based on the analysis of the norms of the Constitution of the Russian Federation, as well as the norms of financial law, it can be concluded that of all types of financial legal relations, the Russian Federation independently participates only in budgetary legal relations. In budget law, the state has not only responsibilities for regulation, distribution and control, but also rights, among which the main thing is the right to its own budget. The federal budget is not the budget of any authority that drafted or adopted it, but represents a form of education and spending of funds throughout Russia, and in this context covers all subjects of law at the level: public entities, authorities, legal entities and individuals. Consequently, through budgetary powers, the Russian Federation interacts with all subjects of financial law, involving them, directly or indirectly, in legal relations regarding public funds.
Improving tax control: tax risks and control data
Authors: Orlova N. Yu.
Published: September 2024

The article is devoted to new opportunities for using digital technologies of the Federal Tax Service, analysis of changing, in connection with this, requirements for accounting programs, innovative methods of conducting analytical work of tax authorities to identify deviations and gaps in key reporting indicators, financial statements provided by taxpayers with others available to tax controllers , databases. Within the framework of the article, the author reveals changes in tax and financial reporting requirements that came into force in 2024 and provides recommendations regarding possible risks that the Federal Tax Service pays attention to during desk audits. The author also formulates how taxpayers should act in order to protect their organization from claims and sanctions of the Federal Tax Service.
Earthquake Magnitude Estimation through Mixed-Effects Ground-Motion Modeling of Early P-Wave Arrivals
Authors: Sharma Nitin , Ravi Kumar Mangalampally , Vijaya Raghavan Raman
Published: September 2024

A regional earthquake early warning system (EEWS) warrants potential predictive models to accurately extract earthquake parameters like magnitude and intensity from the first few seconds of a P-wave arrival. In this study, a maiden predictive model depicting the relationship between peak displacement amplitude (Pd) and magnitude (ML) is proposed for the western Himalayan region through a mixed-effects regression and compared with those from similar tectonic regimes. This model for EEWS is derived from the vertical-component waveforms with a high signal-to-noise ratio, using three different time-window lengths (Td) of 1, 2, and 3 s, just after the P onset. Waveforms from 83 earthquakes in the magnitude (ML) range of 3 and 5.5 registered at 27 strong motion seismic stations are used for this purpose. The hypocentral distance range varies between 5 and 264 km. A comparative analysis between the models obtained through linear and linear mixed-effects (lme) regression reveals that the latter is robust. It is observed that the intra-event uncertainties are significantly reduced after site corrections and contribute more toward the total variabilities, compared to the inter-event uncertainties. Based on the results from this study, it is emphasized that the local site effects should be incorporated while developing the predictive models for EEWS. Importantly, the displacement magnitude (Mpd) derived from Pd values, accurately matches with ML, even for the data not used to derive the model, lending credence to the final model. A scaling relation between the peak ground velocities (PGV) and Pd values is also established to evaluate the seismic hazard levels. Advocating that the adapted models should be calibrated for a targeted region, the dissimilarities among different models and the implications from epistemic uncertainties are also discussed in the present study.
Safety and efficacy evaluation of plain OTC-HCL in acute and subacute toxicity tests and infected mice
Authors: Pharande Rajesh Raghunanth , Mane Shubham Tukaram , Gandge Rajashree Shivkumar , Gulavane Sarita U , Sole Sushant S. , Thorat Varsha D
Published: September 2024

The study aimed to evaluate the safety and efficacy of plain Oxytetracycline hydrochloride (OTC-HCL) in mice experimentally infected with 544 strain.

The safety of plain OTC-HCL was assessed through acute and subacute toxicity testing. The LD value was determined, and hematologic, biochemical, and histopathological analyses were performed. For efficacy evaluation, mice were intraperitoneally injected with 3 × 10^6 CFU of 544 in 0.5 ml. Following infection, the mice received 25 mg/kg of plain OTC-HCL intravenously either daily or on alternate days for 21 days, starting from day 14 post-infection. Efficacy was assessed by measuring the logarithmic decrease in counts in the liver, lymph nodes, and spleen on days 1, 7, and 14 after treatment.

Plain OTC-HCL has an LD of greater than 250 mg/kg. In both acute and subacute toxicity evaluations, the hematologic and biochemical data of the drug were within the normal range. Histopathology studies revealed no significant changes in the safety studies. In the subacute toxicity study, the drug was administered to mice received plain OTC-HCl @ 25 mg/kg intravenously for 21 days. Efficacy was measured by the decrease of counts in the liver, lymph nodes, and spleen.

Plain OTC-HCL was found to be safe in both acute and subacute toxicity tests and effectively reduced the infection load of in mice. Our findings and novelties are 1) LDis more than 250 mg/kg for plain OTC-HCL by intravenously as a single dose. 2) Histopathology indicates that there is no organ toxicity for plain OTC-HCL in safety studies. 3) Plain OTC-HCL was found to be effective in reducing the infection load in -infected mice.
Study on the role of iron chelators in the management of iron overload among transfusion-dependent thalassemia (TDT) pediatric patients
Authors: Krishnakanth K  , Abubakar Shaik Mohammad , Chopra Jhansi Vani , Elizabeth B
Published: September 2024

This study aims to investigate the efficacy and safety of Deferasirox, an oral iron chelator, in reducing iron burden in pediatric patients with transfusion-dependent beta-thalassemia. Thalassemia syndromes, particularly beta-thalassemia, are inherited hemoglobin disorders requiring regular blood transfusions, leading to iron overload and subsequent complications. Effective management of iron overload is crucial to prevent morbidity and mortality.

It was a descriptive observational study on Children between the ages of 2 years and 12 years who present with transfusion-dependent thalassemia and areon blood transfusion and develop iron overload, which is evaluated by serum ferritin levels of more than 2000mcg/l are administered iron chelator Deferasirox (14 mg/kg/d)and patients are evaluated for myocardial, hepatic, pancreatic iron burden and conditions of iron toxicity with the help of Cardiac MRI T2, LIC (Liver Iron Concentration), MRI T2 Pancreas, LVEF (Left Ventricular Ejection Fraction).

A total of 22 patients enrolled in the study; significant reductions were observed in mean serum ferritin levels (2,388 mcg/dl to 2,054 mcg/dl, p=0.0009), transferrin saturation (70.45% to 64.32%, p=0.00005), and serum transaminases (44.55 U/L to 40.27 U/L, p=0.003) at 6 months. Cardiac MRI T2* increased from 19.55 ms to 22.95 ms (p=0.045) at the end of 6 months and at the end of 12 months from 19.55 to 28.23 (p=0.0016), and LIC reduced from 20.73 mg Fe/g dw to 11.59 mg Fe/g dw (p=0.00005). Pancreatic T2 improved from 15.96 ms to 20.23 ms at 12 months (p=0.007). A transient increase in serum creatinine was observed at 6 months from 0.64+/-0.14 mg/dL to 0.7+/-0.13mg/dL(p=0.009), which returned to normal at the end of 12 months to 0.63 mg/dL, no additional therapy-related adverse events were reported.

Deferasirox has demonstrated significant efficacy in reducing iron overload in pediatric patients with transfusion-dependent beta thalassemia over a 12-month period. The substantial improvements in serum ferritin, cardiac MRI T2*, LIC, transferrin saturation, and pancreatic T2, coupled with its excellent safety profile, support the use of DFX as a cornerstone in the management of iron overload in this vulnerable population.
Las enseñanzas de los cuentos de hadas durante las censuras de Franco y Salazar
Authors: Tena-Fernández Ramón , Reis da Silva Sara
Published: September 2024

La literatura infantojuvenil pasó de ser despreciada en los inicios de las dictaduras de España y Portugal a convertirse en objeto de atención preferente en los años cincuenta y sesenta. Sin embargo, se desconoce cuál fue la tolerancia de ambos regímenes hacia los cuentos de hadas, pues, aunque presentaban conceptos identitarios como: familia, religión, y capacidad de sacrifico, los ejemplos no eran los más favorables para su ideario sociopolítico. Por tanto, en este artículo nos interesamos por tres objetivos: 1) identificar qué contenidos se sancionaron en los cuentos de hadas; 2) valorar las diferencias censoras entre los dos países; 3) explorar cómo juzgaron los censores la integración del catolicismo en los cuentos de hadas. Los resultados de este estudio cualitativo de carácter exploratorio emanan del cotejo de los expedientes consultados en el Archivo General de la Administración y el Arquivo da Torre do Tombo (Portugal).
Design and Simulation of a Nanoscale Threshold-Logic Multiplier
Authors: Sulieman Mawahib Hussein , Mahmoud Mariam , Raafat Remonda , Reda Gehad
Published: September 2024

Multiplication is one of the most important operations in microprocessors and digital signal processing systems. Different multiplier architectures have been proposed in the literature. One of the most widely used architecture is the Wallace tree multiplier. This multiplier is known for its high speed. However, it occupies a large area. In this paper, we used Threshold Logic Gates instead of conventional logic gates to reduce the area. The multiplier was designed in 65nm CMOS technology, and achieved 28% reduction in the number of transistors compared to the one with conventional logic gates. It also achieved a lower power-delay-product.
Optimal Utilization of the School Bench with Regard to the Spinal Column Loading of Pupils in Sitting Position
Authors: Veljovic Fikret , Petrovic Marin
Published: September 2024

The problem of irregular sitting position of pupils during classes in schools occurs in everyday life, depending on the use of a workbench, which results in deepening the problems of a spinal column loading. Spinal load analysis was performed by a software simulation depending on a seating position in the school bench. Processing the data in Excel, the current utilization of the workbench surface was determined and then a new design offered. The results of the work offer a completely new design of the school bench with a special emphasis on the surface of the workbench, as well as the optimum seating position for pupils during classes, resulting in spinal relief and an increased seating comfort.