bluuebunny/crossref_metadata_2025 huggingface dataset:
BENCHMARKING OF ANTIBODY TITRES SELECTIONS USING THE RANKING METHOD
Authors: Kulakov V. Yu. , Pyatkina A. A. , Zybina T. N. , Moroz N. V.
Published: February 2023

Based on the serological monitoring results the humoral immunity level in birds was assessed after the use of three variants of inactivated vaccines against avian influenza, which causative agent is capable of genetic rearrangements and generation of extremely dangerous highly virulent forms. The refore there arise the need for accurate quantitative assessments of antibody titres, their benchmarking against threshold values and statistical analysis of the received results. The serological examinations allow obtaining the selections of antibody titres values, determining the arithmetic or geometric mean values, as well as statistical indicators such as standard deviations, coefficients of variation or standard error of the mean. to the parametric ones, since they are based on the given normal distribution of the elements of a selection. However, this condition is not always met, which leads to the incorrect conclusions, especially when conducting a comparative analysis. Alongside, it should be noted that banchmarking made in a group consisting of more than two selections cannot be made on independent pairs. In this case the special multi-comparative methods are required. The aim of this work was to conduct a comparative analysis of three antibody titres selections. The nonparametric multiple comparison Miller's method was applied, which is designed to detect the essentiality of mean trends differences in selections, regardless of the type of changing variables distribution. According to the method’s algorithm, the entire array of experimental data was integrated into a common rank-ordered (ranked) row, where each variable was assigned a serial number (rank). Respective with the original selections, the variables’ mean ranks were calculated. The mean ranks subtraction results and the necessary statistical operators were determined, which were benchmarked against the table values (the table is attached). Thus, the statistical significance of the discovered results of subtraction was drawn. The method did not require any special mathematical background of the researchers.
FEATURES OF MASTITIS MANIFESTATION IN DAIRY COWS IN THE AMUR REGION
Authors: Ostyakova M. E. , Kositsyna K. S. , Irkhina V. K. , Golaydo N. S.
Published: February 2023

One of the main factors hindering the growth of milk productivity and deteriorating the sanitary quality of farm produced milk is mastitis. Mastitis can occur during lactation, drying off and interlactation periods but more often during the lactation period, when the mammary gland is under enormous exertion. The aim of the research was to study the features of mastitis manifestation in dairy cows under the Amur region conditions. Samplings were carried out in September-October. Milk was analysed using the Masttest rapid diagnosticum. Studies showed that mastitis was not diagnosed in 39.1 % of cows, in 20.3 % of cows it was dubious (lesion of the posterior udder lobes). In 40.6 % of cows the mastitis was diagnosed in the form of lesion of the posterior udder lobes, whereas the anterior udder lobes showed dubious result. The mastitis positive diagnosis in cows in at least one lobe of the udder may indirectly indicate the presence of subclinical mastitis in the remaining udder lobes or the transformation of the subclinical form of mastitis into clinical one under the influence of unfavourable external factors and in the absence of therapy.
VETERINARY AND SANITARY ASSESSMENT OF THE MEAT FROM ANIMALS AFTER ORAL ADMINISTRATION OF THE ANTIPARASITIC DRUG «DEGELM-16»
Authors: Gizzatullin R. R. , Mingaleev D. N. , Lutfullin M. Kh.
Published: February 2023

The paper presents veterinary and sanitary assessment of the meat from rabbits and pigs, who had taken a new anthelmintic drug «Degelm-16» in their diet. The meat from 6 rabbits and 6 gilts who were divided into experimental and control groups was studied, three samples per each group. The drug «Degelm-16» was given alimentary with foodstuff to the animals of the experimental group 5 days before the slaughter at a dose of 50 mg/kg. Rabbits and gilts of the control group did not receive the drug. It was discovered that meat samples taken in the control and experimental groups of rabbits and gilts contained a drying crust, elastic muscle fibers. The characteristic smell of test samples corresponded to the specimens species. Meat samples from both animal species were of pale pink colour. Boiling of the meat from rabbits and gilts resulted in cloudy-white broth with pleasant specific smell. The benzidine reaction revealed a peroxidase positive result in the meat extract. The amount of amino-ammonia nitrogen in both rabbit groups ranged from 0.54 to 0.60 mg, in gilt groups – from 0.76 to 0.79. The volume of volatile fatty acids in rabbit meat samples ranged from 1.82 to 1.89 mg KOH. In gilt meat – from 2.19 to 2.43 mg KOH of volatile fatty acids. The reaction for the protein primary decomposition products using copper sulphate in both groups resulted in getting the broth without clots and flakes confirming appropriateness of the meat. The touch smears bacterioscopy showed presence of single microorganisms in the surface layers and complete absence of the bacteria in the deep layers. The data of microbiological analysis did not reveal deviations from the reference values.
ZEMSTVO SYSTEM VETERINARY MEDICINE OF THE OSTROGOZHSK COUNTY OF THE VORONEZH
Authors: Skvortsov V. N. , Gorbaneva A. S. , Oskolskaya V. Yu. , Kravtsova A. R.
Published: February 2023

Until 1891 the entire territory of the Ostrogozhsk County was covered by a single veterinary district. Based on the Zemstvo Assembly Resolution, starting from that year the county was divided into two veterinary districts – Rossoshansk and Ostrogozhsk. The Rossoshansk district included 15 volosts (small rural districts): Lizinovsk, Olkhovatsk, Rossoshansk, Rovensk, Aidarsk, Podgorensk, Belogorsk, Shaposhnikovsk, Evstratovsk, Vsesvyatsk, Maryevsk, Karayashnikovsk, Semeysk, Novo- and Staro-Kalitvyansk. The Ostrogozhsk district included the town and 12 volosts: Goncharovsk, DalnePolubyansk, Evdakovsk, Karpenkovsk, Kolybelsk, Lisyansk, Lushnikovsk, Markovsk, Novo-Sotensk, Ribensdorfsk, Sagunovsk and Trostyansk. The third Rovensk veterinary district was opened in 1897 to include seven volosts: Aidarsk, Lizinovsk, Rovensk, Shaposhnikovsk, Vsesvyatsk, Maryevsk and Olkhovatsk. In December 1897 the Olkhovatsk veterinary paramedical station was eliminated due to the paramedic's resignation. In February 1901, a veterinary outpatient clinic was opened in the town of Ostrogozhsk. From March 10, 1903, the veterinary staff of the first district increased by one paramedic, who was appointed by the Province Zemstvo to an independent station in the Marky village. The fourth Sagunovsk veterinary district was opened in 1906 to include six volosts: Sagunovsk, Markovsk, Belogorsk, Karayashnikovsk, Goncharovsk and Kolybelsk. In October 1907, the Olkhovatsk volost, which was recorded as part of the Rovensk district was assigned to the Rossoshansk. On August 1, 1909, the fifth Podgorensk district was opened in the county. There were two inpatient clinics in the county – in Saguny and Rovenky. In November 1910 the sixth district was opened in Staraya Kalitva village. In 1913 the seventh Olkhovatsk veterinary district was opened and new distribution of volosts and villages took place within the county territory. As of the beginning of 1914 seven veterinary physicians and twelve paramedics worked in the county. The First World War which began in July 1914, stopped the progressive evolution of zemstvo system veterinary medicine in the county as most of the physicians and paramedics were mobilised into the army.
Design and Performance Analysis of an Oil Pump Powered by Solar for a Remote Site in Nigeria
Authors: Chidolue Onyinyechukwu , Iqbal M. Tariq
Published: February 2023

Oil companies typically abandon stripper wells with production rates below 15 barrels per day because the production and maintenance cost exceed the pumping rate. Oil spillage is the primary cause of low production rates; an example of such failure is the Oloibiri oil well in Nigeria. During the peak of operation, the flow rate was 5,100 barrels per day in 1960 and was abandoned due to the declining production rate. The Oloibiri oil site has 18 drilled wells, and only the oil well 17 can be classified as stripper well. Because Nigeria has high solar irradiance and insolation, a proper PV system sizing for a solar-powered pump that should lift oil from a depth of 3800 metres at a flow rate of 15 barrels per day is evaluated for two different running times. In that way, the solar-powered pump will be used to solve the ongoing issue of stripper oil wells by curbing oil spillage from the oil wells abandoned by these production companies and rendering a low-cost pumping system. This paper evaluates the pump performance and completes the system design. It compares the system design to the PVsyst and HOMER sizing.
Analysis of Diversion Arrangements in the Beijing Rules and the Juvenile Criminal Justice System in Indonesia
Authors: Nurqalbi Vivi
Published: February 2023

Diversion is very important to pay attention to in handling children of delinquent perpetrators, because it can prevent children from the stigmatization process that usually occurs in the process of criminalizing children through the juvenile justice system. In terms of protecting the best interests of children, diversion arrangements can be found in several international legal instruments such as The Beijing Rules, and in national legal instruments such as the Juvenile Criminal Justice System Act. The purpose of this study is to examine the diversion arrangements in The Beijing Rules and their arrangements in the Law on the Juvenile Criminal Justice System in Indonesia, then to examine these two arrangements. The research method used is normative legal research using statutory, conceptual, and comparative approaches. The results of the study show that the purpose of diversion in The Beijing Rules is not fully seen in the Law on the Juvenile Criminal Justice System. Because even though the provisions for diversion have been regulated, the existence of space that diversion can be pursued at the stages of investigation, prosecution and examination at trial has resulted in cases still being included in the juvenile justice system by giving a stronger stigma to children who are in conflict with the law.
Investigasi Potensi Warisan Arsitektur untuk Pariwisata: Studi Kasus Hotel Salak Kota Bogor
Authors: Hastjarjo Hastjarjo , Prihantono Agus , Utami Nisa Rahmaniyah
Published: February 2023

In the past, in front of Bogor station there was a horse carriage from hotels to pick up guests who came. There were three luxury hotels that used to exist in Bogor; (1) Hotel Du Chemin De Fer on Jalan Capt Muslihat, now the Bogor Police Station, (2) Hotel Bellevue at the turn of Jalan Ir H Juanda, now Mall BTM, and (3) Hotel Dibbets (1856), later changed its name to NV American Hotel (1913) and Bellevue Dibbets (1932), still operating as Hotel Salak and are the only legendary hotels in Buitenzorg. This paper aims to support the preservation of architectural heritage in the city of Bogor, especially Hotel Salak as an inseparable part of the history of the city of Bogor by synergizing the study of conservation potential and the economic value of architectural heritage tourism (AHT). The methodology of this research is a case study of single identification of Hotel Salak Bogor as a bounded system of AHT. AHT stakeholders; The Tourism Office, Hotel Operators, and Academics must work together in conservation and tourism development, because AHT = conservation + tourism potential
Pengaruh Kualitas Produk Makanan Terhadap Kepuasan Konsumen pada Restoran Hotel Salak The Heritage Bogor
Authors: Ishak Riani P. , Utami Nisa Rahmaniyah , Kurniawan Taufiq
Published: February 2023

This study aims to determine and analyze the effect of product quality on customer satisfaction at the Hotel Salak The Heritage Bogor restaurant. Dimensions of product quality measured include presentation, menu variety, healthiness, delicacy, freshness and temperature.  Dimensions of customer satisfaction measured are tangibles, reliability, responsiveness, empathy.  This study uses a quantitative approach method. Collecting data using primary data through non-probability sampling/insendental sampling as many as 100 respondents who are guests who visit the restaurant. Data analysis in this study used simple linear regression with SPSS application, all research data were verified through all statistical tests. The results showed that the quality of food products has a positive and significant effect on customer satisfaction at the Salak Hotel Restaurant The Heritage Bogor.
Atraksi Pariwisata dalam Mengembangkan Pariwisata Mandeh di Kabupaten Pesisir selatan Sumatera Barat
Authors: Husna Rifdatul , Zengga Zengga
Published: February 2023

This Paper aims to analyze tourism attractions in developing Mandeh Tourism in Pesisir Selatan District, West Sumatra Province. Data collected from 5 interviewed data sources and 93 respondents using a questionnaire. The research method uses descriptive qualitative methods and SWOT analysis supported by quantitative data in the form of questionnaire data processed using excel. Based on this research, an analysis of tourism attractions in developing tourism is obtained from the elements of attractions: natural beauty, culture and history. By carrying out an analysis (SWOT) to find out what has the potential for tourism attractions in developing the Mandeh Tourism object in Pesisir Selatan Regency.
Pengaruh Tuturan Afasia terhadap Leksikal pada Tuturan Penderita Afasia: Suatu Kajian Neuro-Fonologi
Authors: Johan Mhd. , Satria Robby , Oktavia Yunisa
Published: February 2023

This study aims to explain the lexical forms and how the speech processes are produced by the respondents. This study involved respondents who experienced speech disorders, especially respondents who experienced aphasia. Several things are of particular concern in this research, especially the fading process, then the replacement process. Usually this change process is the most dominant thing in this case study.The next process is the added process, where this process is often also found in speech, sometimes the meaning is lost or meaningless. This study uses references such as the opinion of Sastra, Johan, and many other supporting theories that complement the validity of this research. In the implementation of this research, the method of participatory observation was used in the process of collecting data and completed with baiting techniques to lure respondents to speak. For data analysis, the distribution method is used, in other words, it is called the distribution method which is equipped with several techniques such as deletion, expansion, and replace techniques. From the technique will produce three processes.
A Functional Analysis of Inversion in English Sentences
Authors: Hadi Muhammad Zaki Pahrul , Syamsurrijal Syamsurrijal
Published: February 2023

Inversion is defined as the appearance of the main verb before the subject of an utterance. Using descriptive qualitative approach, this research analyzed phenomenon of language which happens at present. The object of this research is the inversion systems in English. The sources of the data are taken from English books, papers and other resources such as TOEFL test preparation books that related to the topic. In gathering data, the researcher used two techniques namely teknik catat (noting technique) and teknik pisah (separating technique). The result of analyses showed that there are six types of inversion system in terms of forms namely; inverting the main verb to subject, inverting auxiliary verb to subject, adding the auxiliary verb preceding the subject, Inverting the adverb and the subject, Inverting the preposition and the subject, Sentence beginning with there. Meanwhile types of inverted sentence are classified into six. They are interrogative sentence, conditional sentence, statement, comparative sentence, exclamation, reporting sentence. In term of function, there are three functions of inversion namely, emphasizing the negative expression, emphasizing the time expression, and as a variation.
Yang Terampas dan Yang Terputus: Guru dan Menulis Ilmiah
Authors: Adek Muhammad , Pangesti Nesa Riska , Nabila Jeihan , Zulfikarni Zulfikarni
Published: February 2023

Profesi Guru sudah ada semenjak Indonesia merdeka. Selama itu, guru identik dengan pendidik yang berfokus pada pengajaran, pembimbingan, motivasi dan evaluasi kepada siswa. Saat ini, seorang guru profesional diwajibkan untuk menghasilkan publikasi ilmiah baik dalam bentuk buku, artikel maupun makalah yang didiseminasikan dalam forum ilmiah. Tidak sedikit dari guru menghindari dan menyepelekan kegiatan menulis ilmiah ini sehingga kuantitas dan kualitas tulisan ilmiah yang dihasilkan guru masih jauh dari harapan. Hal ini secara tidak langsung menggangu proses perbaikan kualitas guru, kualitas sekolah hingga kesejahteraan dari guru itu sendiri. Makalah ini bertujuan untuk mendiskusikan keengganan guru sekolah dasar dalam menulis ilmiah berdasarkan data yang dikumpulkan selama kegiatan pengabdian masyarakat di kota Solok. Hal ini diharapkan menjadi catatan penting bagi perguruan tinggi, pemerintah daerah dan kementerian untuk bersama-sama mengevaluasi kesulitan yang dialami guru untuk didapatkan solusi di masa mendatang.
Verbal Responses toward Insults in the Celebrity Read Mean Tweets Segment
Authors: Muflihatunnisa Muflihatunnisa
Published: February 2023

Receiving insults virtually is one of the drawbacks of living with cutting-edge technology. Drawing on insults, the study’s objectives are to examine the verbal responses toward insults and the language features employed by the celebrities in the ‘Celebrity Read Mean Tweets’ segment on the Jimmy Kimmel show on Youtube. The data are verbal responses by 50 participants taken from the talkshow’s account. The analysis was carried out qualitatively by adopting the frameworks of Bond and Venus’ verbal responses accompanied by the gender language features of Lakoff and Coates. The results suggested that verbal responses were mainly employed to resist the insults. The strategies of resisting were conducted mostly via antinomies, correcting, and swearing. To signalize their acceptance, the speakers mostly appreciate the quality of the insult. Other purposes of the verbal responses were to ignore the insults which were done predominantly via digression. Subsequently, the highly employed language feature by the celebrities was lexical hedges/fillers and harsh words/swearing. Most of the features were used altogether by both genders, except for empty adjectives which were discovered from female responses. The results of this study can help explore strategies to tackle insults and future research related to verbal responses.
IMPLEMENTASI LKPD FISIKA PADA MODEL PEMBELAJARAN PREDICT OBSERVE EXPLAIN UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS SISWA
Authors: Ningrum Astri , Putri Desy Hanisa , Medriati Rosane
Published: February 2023

LKPD berbasis Predict Observe Explain merupakan LKPD yang dapat memberikan infomasi kepada guru agar mengetahuai bagaimana cara berpikir peserta didik, menemukan ide, dan juga memotivasi peserta didik untuk mencari pengetahuan konsep yang mereka milik. Pembelajaran di kelas hanya beberapa siswa yang aktif dan antusias dalam proses pembelajaran dan masih ada beberapa siswa yang nilainya belum tuntas. Penelitian bertujuan untuk mendeskripsikan peningkatan dan perbedaan kemampuan berpikir kritis siswa terhadap implementasi LKPD Fisika pada model pembelajaran Predict Observe Explain materi getaran harmonis di SMAN 6 kota Bengkulu. Populasi penelitian ini adalah siswa kelas X MIPA SMA Negeri 6 Kota Bengkulu tahun ajaran 2021/2022 semester genap. Jumlah sampel sebanyak 35 orang siswa yang di ambil melalui teknik random sampling. Adapun jenis penelitian merupakan penelitian pre-eksperimental dengan menggunakan rancangan penelitian one group pretest-posttest. Instrument yang digunakan dalam penelitian adalah observasi, wawancara, dan tes kemampuan berpikir kritis. Hasil penelitian menunjukkan bahwa penggunaan LKPD Fisika berdasarkan perhitungan N-Gain adalah 0,57 dengan kategori sedang. Berdasarkan analisis data pada penelitian didapatkan kesimpulan bahwa antara skor pretest sebelum menggunakan LKPD fisika pada model pembelajaran Predict Observe Explain untuk meningkatkan kemampuan berpikir kritis dan skor posttest setelah menggunakan mengalami perbedaan yang signifikan
PERBEDAAN HASIL BELAJAR SISWA MENGGUNAKAN MOODLE DENGAN EDMODO
Authors: Simanjuntak Mariati Purnama , Simbolon Magdalena
Published: February 2023

Penelitian bertujuan mengetahui perbedaan hasil belajar siswa dengan penerapan learning management system (LMS) berbasis moodle, edmodo dan dengan pembelajaran konvensional. Populasi penelitian siswa kelas X yang terdiri dari 9 kelas yang berjumlah 270 siswa di salah satu sekolah di Sumatera Utara. Sampel penelitian diambil tiga kelas yaitu; kelas X MIA-4 untuk kelas eksperimen , kelas X MIA-5 untuk kelas eksperimen  dan kelas X MIA-9 untuk kelas kontrol (y), masing-masing kelas berjumlah 20 orang siswa.  Jenis penelitian eksperimen semu menggunakan desain three group pretest-posttest. Instrumen terdiri dari tes pilihan ganda sebanyak 20 soal yang sudah divalidasi. Hasil nilai pretest kelas eksperimen  sebesar 31,50, kelas eksperimen  sebesar 32,50 dan kelas kontrol (y) sebesar 27,50. Hasil nilai post-test kelas eksperimen  sebesar 85,00, kelas eksperimen  sebesar 82,75 dan kelas kontrol (y) sebesar 67,25. Persentase peningkatan N-gain hasil belajar kelas eksperimen  sebesar 78% kategori tinggi, kelas eksperimen  sebesar 74% kategori tinggi, dan kelas kontrol (y) sebesar 53% kategori sedang. Berdasarkan hasil uji anava satu arah terdapat perbedaan hasil belajar siswa dengan penerapan LMS berbasis moodle, edmodo dan konvensional. Berdasarkan uji beda (uji-t) diperoleh: 1) hasil belajar dengan penerapan LMS berbasis moodle lebih baik daripada penerapan edmodo dan pembelajaran konvensional; dan 2) hasil belajar dengan penerapan LMS berbasis edmodo lebih baik daripada konvensional.
DEVELOPMENT OF MULTIPLE REPRESENTATION BASED E-MODULS TO IMPROVE ABSTRACT THINKING SKILLS PHYSICS OF HIGH SCHOOL STUDENTS
Authors: Fauziah Rosynanda Nur , Raisal Abu Yazid
Published: February 2023

Students' multi-representational understanding in understanding glasses needs to be raised by educators in various forms of presenting information so that students are able to understand an abstract problem to become concrete in all realms of reflection. One way to apply learning with a multi-representational approach can have a positive influence on students' cognitive abilities which include low cognitive levels and high cognitive levels. The purpose of this research is to develop an e-module of  based on multiple representations for high school students' abstract thinking skills. This is to determine the success of module development that has been designed in such a way. The research method used is research and development or research and development. The model used in the development of this e-module is a 4D model which consists of four stages of development, name define, design, develop, and disseminate. The stages used in the development of this e-module reach the develop stage, due to research limitations and in accordance with the research objectives, namely the development of e-modules. From the results of the research and discussion, it can be concluded that several representation-based e-modules to improve the abstract thinking skills of high school students that have been compiled are of good quality and still need to be achieved. . The average test results of material validation experts stated that the module was in the good category with an average value of 3.5 on a Likert scale, then for the media validation results it was also with an average of 3.5 and said to be in a good category
Improving methods of studying graphic disciplines for students of technical specialties and directions
Authors: Kozlova Irina Alekseevna , Guseva Tamara Viktorovna , Khmelnitsky Konstantin Evgenievich
Published: February 2023

In modern development of digital technologies education faces a difficult task: translation of previously accumulated knowledge and meeting the demands of the digital future in the XXI century. Digital transformation of education involves changing the ways and methods of teaching, as well as changing the subjects of education - the teacher and the student. A convenient tool of influence between a student and a teacher is a modular virtual educational platform (for example, Moodle), which allows studying the theoretical material, conducting practical classes and examinations. Combination of various technological techniques confirms the availability of their implementing for improving the quality of education in accordance with the Federal State Educational Standards, allows improving the quality of education in the context of a dynamically developing society. Certain approaches to the graphic training of students have been stated. Modeling the geometric shapes on the screen, in contrast to the traditional approach, develops the intellectual, cognitive and creative abilities of students, in most cases having insufficient graphic training. Working with graphics packages is impossible without the knowledge that is acquired in practical classes of Engineering Graphics. Actually, at the university engineering training is aimed at developing the skills of creating an information model of an object and forming project documentation based on it. Introducing the innovative methods and forms of education creates a new strategy of vocational training in a technical university. When studying the sections of mechanical engineering drawing, computer visibility allows to see the technical forms of the details, gives an idea of the manufacturing technology, control and assembly of products, which will help the student to correctly perform cuts, sections of parts, correctly apply the dimensions on the drawings. There have been illustrated the examples of using engineering graphics in the technological processes of manufacturing the soundproof hood “KAPONISTR” for outboard boat motors. It has been inferred that the computer visual aids are important in training the engineers by using active teaching methods.
Artikel Review: Aktivitas Imunomodulator Tanaman dari Suku Asteraceae
Authors: Mei Kaila Keyshia , Iskandar Yoppi
Published: February 2023

Imunitas merupakan suatu reaksi pertahanan tubuh terhadap bahan asing, terdapat suatu kondisi dimana sistem imun dapat terganggu sehingga menyebabkan penyakit seperti autoimun, alergi, dan imunodefisiensi. Saat ini terdapat obat sintetik yang dapat mengobati kelainan imun, tetapi obat sintesik memiliki efek samping. Sehingga diperlukan pengobatan alternatif yang penggunaannya dinilai lebih aman. Asteraceae merupakan suku tumbuhan terbesar kedua dalam kingdom Plantae yang tersebar luas di seluruh dunia. Penulisan artikel ini bertujuan untuk memberikan informasi ilmiah beberapa tanaman dari suku Asteraceae yang memiliki aktivitas imunomodulator. Metode yang digunakan dengan cara pencarian pada aplikasi Google Chrome secara daring yang berasal dari Google Scholar, PubMed, ResearchGate, situs jurnal lain. Terdapat beberapa tanaman suku Asteraceae yang memiliki aktivitas imunomodulator diantaranya Ageratum Conyzoides (L.); Artemisia annua L.; Artemisia argyi H. Lev. & Vaniot; Baccharis dracunculifolia DC.; Chromolaena odorata (Lf.) King & Robinson; Cichorium intybus L.; Cynara scolymus L.; Echinacea laevigata (C. L. Boynt. & Beadle) S.F. Blake; Echinacea purpurea (L.) Moench; Echinacea purpurea (L.) Moench; Erigeron floribundus (Kunth) Sch.Bip.; Psacalium peltatum (Kunth) Cass.; Tanacetum parthenium (L.) Sch.Bip.; Tridax procumbens L.Kata kunci: Asteraceae, Imunomodulator, Sistem imun
Health Benefits of Three Wild Leafy Vegetable in “Lalapan” as Sundanese Traditional and Ethnic Foods
Authors: Kodir Reza Abdul , Moektiwardoyo Moelyono
Published: February 2023

Various ethnics of the world have a long history on using their surrounding as the source of foods. Foods which are act as product of traditional ethnic knowledge known as traditional and ethnic foods (TEF). Vegetables are one of the main ingredients of TEF. As sources of many combination of phytonutrients, vegetables offer various health benefits. As a country with long history of agricultural practice, Indonesia also has abundant knowledge of how Indonesian ethnics process and consume vegetables.Vegetables, in Sundanese tradition, usually consumed as “lalap” or “lalapan”. Some lalapan are cultivated vegetables and some others are come from wild sources. This article discuss the health benefits of wild source lalapan, which can be found in natural habitat.
Artikel Ulasan: Kandungan Senyawa Kimia dan Aktivitas Farmakologi Spirulina sp.
Authors: Kamaludin Asilla M. R. , Holik Holis A.
Published: February 2023

Spirulina sp. merupakan mikroalga hijau-kebiruan yang mempunyai berbagai manfaat karena kandungan senyawanya yang beragam diantaranya protein, mineral, vitamin, serat, pigmen phyocyanin, asam lemak tak jenuh, beta karoten, tiamin, nicotinamide, piridoksin, riboflavin, asam folat, fitokimia fenolik, fikobiliprotein, catechin hidrat, epicatechin, pyrocatechol, dan enzim superoksida dismutase (SODArtikel ini bertujuan untuk memberikan iformasi ilmiah mengenai kandungan senyawa kimia dan aktivitas farmakologi Spirulina sp. Metode yang digunakan yaitu pengumpulan dan skrining data dengan kriteria inklusi dan eksklusi. Hasil yang diperoleh yaitu informasi mengenai kandungan senyawa kimia yang terkandung serta aktivitas farmakologi yang ditimbulkan memiliki aktivitas imunomodulasi, antioksidan, antikanker, antitumor, antimikroba, antiinflamasi, penurun berat badan, antidiabetes, penurun kosentrasi serum lipid, berperan dalam bone modeling dan pertumbuhan serta perkembangan anak.Kata Kunci: Spirulina sp., kandungan senyawa, manfaat Spirulina sp.
Artikel Ulasan: Tanaman Sebagai Anti-Kolesterol
Authors: Azzahra Ratu W. , Zuhrotun Ade
Published: February 2023

Kolesterol merupakan lipid dalam darah yang diproduksi oleh hati. Kolesterol juga merupakan faktor resiko dari penyakit kardiovaskular. Pada tahun 2018 dilaporkan 1,5% dari penduduk Indonesia yang setara dengan 1.017.290 jiwa menderita penyakit kardiovaskular dan diperkirakan akan terus bertambah setiap tahunnya. Ini mengakibatkan permintaan akan obat anti kolesterol pun semakin tinggi. Artikel tinjauan ini dibuat untuk mengkaji tanaman yang memiliki potensi dan khasiat sebagai anti kolesterol yang bisa menjadi pencegah maupun pelengkap obat sintetik. Metode yang dilakukan yaitu dengan melakukan pencarian secara daring pada e-book, e-journal, dan website dari situs resmi yang valid seperti Google Scholar dan National Library of Medicine terkait anti kolesterol beserta nama tanamannya. Hasil yang didapat atas pencarian tersebut terdapat minimal 30 tanaman yang berkhasiat sebagai anti kolesterol. Berdasarkan urutan potensi tanaman dengan khasiat tersebut, mayoritas berasal dari famili zingiberaceae. Tanaman dengan potensi kuat antara lain yaitu Jahe (Zingiber officinale Rosc.), Kunyit (Curcuma domestica L.), dan Kesum (Polygonum minus Huds) dengan nilai IC50-nya secara berturut-turut sebesar 0,1 ± 0,1 µg/mL; 0,9 ± 0,1 µg/mL; dan 1,2 ± 0,1 µg/mL. Tanaman dengan potensi sedang yaitu Mindi (Melia azedarach), Ampelas (Ficus exasperata), dan Temulawak (Curcuma xanthorrhiza) dengan nilai IC50 secara berturut-turut sebesar 10,48 μg/mL; 14.7 μg/mL; 16,21±1,74 μg/mL. Serta tanaman dengan potensi lemah yaitu Ciplukan (Physalis angulata), Rukam (Flacourtia rukam), dan Salam (Syzygium polyanthum (Wight) Walp) dengan nilai IC50 secara berturut-turut sebesar 149,46 µg/mL; 157.88 µg/mL; 196,7 µg/mL.Kata Kunci: Anti-kolesterol, Tanaman Herbal, Low-density lipoprotein (LDL)
Artikel Ulasan: Potensi Herbal Sebagai Fitoterapi Pada Epilepsi
Authors: Sitinjak Bernap D. P , Zuhrotun Ade
Published: February 2023

Epilepsi merupakan penyakit neurologis dengan tingkat paling membebani kelima di dunia. Prevalensi epilepsi di dunia meningkat hampir dua kali lipat dari tahun 1990 (34%) ke tahun 2016 (63%). Penulisan artikel ini dilakukan untuk memberikan informasi terkait herbal yang memiliki potensi sebagai alternatif antiepilepsi dan telah diujikan secara in vivo. Metode yang digunakan adalah pencairan literatur terlebih dahulu dengan kata kunci “aktivitas antiepilepsi”/” antiepileptic activity”, “tanaman”/” plants”, “in-vivo” pada kolom pencarian database Google Scholar dan PubMed lalu dilakukan inklusi berdasarkan relevansinya. Adapun hasil dari review artikel yaitu diperoleh 24 spesies tanaman dengan aktivitas agonis GABAergik (20 spesies tanaman), antioksidan (9 spesies tanaman), inhibisi kanal ion Na+; K+ (4 spesies tanaman), dan inhibisi kolinergik (4 spesies tanaman). Beberapa diantaranya memiliki senyawa yang mampu melintasi saraf pusat yaitu isokuersetin- 3 -O-glukosida, glabridin, kuersetin, 6-Gingerol, turmeron, dan, bisabolene sesquiterpenoid. Berdasarkan hasil penelitian, Achyranthes aspera Linn memiliki dosis paling berpotensial (5-10 mg/kB, i.p) sebagai anti epilepsi.
Potensi Minyak Rosemari pada Waktu Kematian Caplak secara In Vitro
Authors: Prasetyo Bayu Febram , Hadi Upik Kesumawati , Winarto Tytha Nadhifa
Published: February 2023

Minyak esensial rosemari telah banyak digunakan di berbagai bidang karena manfaatnya bagi kesehatan. Salah satu manfaat yang kurang diketahui adalah sifat antiparasitnya. Penelitian ini bertujuan menganalisis pengaruh pemberian minyak esensial rosemari terhadap waktu kematian caplak Rhipicephalus sanguineus. Pada penelitian ini, 50 ekor caplak dibagi menjadi 5 kelompok dan masing-masing kelompok mendapatkan 5 perlakuan yang berbeda yaitu minyak esensial rosemari konsentrasi 10%, 15%, dan 20% serta antiparasit komersial yang mengandung fipronil 3% sebagai kontrol positif dan minyak kelapa murni sebagai kontrol negatif. Kelompok caplak diamati dalam 3 kali periode masing-masing 30 menit. Kelompok perlakuan minyak esensial rosemari konsentrasi 10% memiliki LT50 pada 2 jam 27 menit, kelompok perlakuan minyak esensial rosemari konsentrasi 15% memiliki LT50 pada 1 jam 10 menit, dan kelompok perlakuan minyak esensial rosemari konsentrasi 20% memiliki LT50 pada menit ke-34. Hasil penelitian ini menyimpulkan bahwa minyak esensial rosemari dalam konsentrasi 20% hampir sama efektifnya dengan antiparasit komersial yang mengandung bahan aktif fipronil 3% yang memiliki sifat akarisidal.
Image of sport tourism Kiara Artha Park Bandung
Authors: Hidayat Dasrun , Gustini Leili Kurnia , Christin Maylanny , Nur’aeni Nur’aeni , Taufik Reza Rizkina
Published: February 2023

Background: Sports tourism is a new approach to growing public interest in sports. Sports tourism is expected to foster interest in sports and build an image of sport tourism as a dual force that can help economic growth. Purpose: The research was conducted at Kiara Artha Park, one of the sports tourism sites in Bandung. The aim is to analyze the stages of forming the image of Kiara Artha sports tourism. Methods: Using a qualitative and phenomenology approach, involving 11 informants: Kiara Artha Park managers, tenants, and visitors. Results: The study results explain that the image built in Kiara Arta Park is a place of recreation with the concept of healthy living. The stages of building the image of Kiara Artha Park begin with the commitment of the management to prepare facilities in the form of green open land designed as a recreational park and exercise. They are also conducting socialization in conventional media, building sports community support, and managing community participation of social media users. Conclusion: The image of Kiara Artha Park as a tourist sport place is built through public awareness as users need a place to exercise and recreation. The two combined concepts encourage interest in maintaining a healthy life. Thus, the type of image formed is a user image or image built by consumers based on personal needs related to personality, lifestyle, and social status. Implications: The results of this study can provide input to the management and government of the city of Bandung as a policy in every tourist destination to provide sport tourism facilities as an additional public space that can improve the physical and mental health of the community.
Graduate income and profession linkage: Tracer study of public relations graduates
Authors: Lukman Syauqy , Rizal Ii , Tiara Olga
Published: February 2023

Background: Higher educational institutions must prepare graduates for careers by monitoring their performance. They must also evaluate academic relevancy to practical needs. The PR program at Universitas Padjadjaran strives to deliver the best education and monitor graduates’ performance. Purpose: This paper aims to study how graduates’ first income is associated with GPA, study duration, and job wait time. This study also linked public relations education with graduates’ current position in their work based on their self-assessment. Methods: Using tracer study data from the Career and Development Centre of Universitas Padjadjaran, exploratory data analysis was done to examine the characteristics of graduates based on the observed variables. The bivariate analysis investigated the association between income, GPA, study duration, and job wait time. Conclusion: Findings of this study show no statistical evidence of the relationship between first salary, GPA, and duration of the study. Exploratory data analysis shows that PR program graduates perform well when comparing the average income of undergraduates on a national level. Graduates’ self-assessment of study relevancy indicated that most graduates possess the relevant educational background and appropriate level of education for their current occupational position. As the statistical testing for this study was conducted post hoc, careful considerations need to be taken when taking the results at face value, considering potential flaws in the sampling frame and the power of the tests. Implications: The findings in this study would serve as a platform for future references on graduates or tracer study, more specifically public relations graduates, as it provides a starting point for measuring graduates’ performances. As the database provides more data with more graduates in future years, an updated finding of this particular study would be very important to measure how well graduates fare post-graduation.
Devenir monstruo: Ensayos sobre narrativa argentina reciente
Authors: Sánchez Silvina
Published: February 2023

El presente volumen indaga las apariciones, figuraciones, genealogías y desplazamientos del monstruo en la literatura argentina de las últimas décadas, tanto en los proyectos estéticos y las poéticas, como en los cuerpos, las subjetividades, las vidas y las formas de lo común que emergen como novedad inusitada en las escrituras. Reconstruye los diálogos irreverentes que las ficciones instauran con la tradición, los textos canónicos, los relatos fundacionales, las figuras, los tópicos y los personajes consagrados, atendiendo al doble movimiento de apropiación y desarticulación, donde proliferan las resignificaciones anómalas e informes. Concebido desde la noción del juego de cuerdas de Donna Haraway, el libro privilegia tres figuras: ópticas, comunidades y mutaciones, para construir una organización dinámica, con líneas de conexión porosas y abiertas, que aspira a dejar intacta la potencia creadora y refractaria del monstruo. A través de mapas, constelaciones y reflexiones teóricas diversas, las lecturas aquí reunidas exploran las transformaciones de la narrativa argentina reciente: el devenir monstruoso de las formas, de las ficciones, de las poéticas y de las lenguas.
Ficções urbanas
Authors: Santana Ethel Pinheiro , Ávila Pâmela Paris , Garro Jorge Alfonso Astorga
Published: February 2023

A evolução da cidade do Rio de Janeiro foi pontuada por influências e impactos que se refletem em sua paisagem e forma urbana atual. A construção do metrô, na década de 1970/80, é um caso de exemplar intervenção urbana que marcou significativamente a morfologia de alguns bairros cariocas. A atual configuração da Rua do Catete é o resultado da combinação de trechos preservados, com edifícios construídos em terrenos remanescentes das demolições e persistência de vazios urbanos, sem clara articulação. O objetivo deste artigo é, portanto, apresentar uma análise das alterações morfológicas verificadas na Rua do Catete, desde 1960, e sinalizar as mudanças promovidas em seuestrato físico e histórico através de narrativas proporcionadas pela justaposição de relatos memoriais. Tal ação visa evidenciar o atual cenário complexo e reforçar a conexão memória/espaço físico/usos e práticas locais, que é parte de uma pesquisa maior, oriunda de dissertação de mestrado. A metodologia de pesquisa se configura através de junção entre abordagem pela forma, estudos por narrativas e o método “Palácio de Memórias” — aplicado à Rua do Catete, ratificando um dos pontos principais para este trabalho: a necessidade de aprender comos registros e modificações urbanas do passado para se compreender as necessidades de hoje. Deste modo, este artigo leva a conclusões quepermitem evidenciar que a desterritorialização e a territorialização dos espaços urbanos precisam ser colocadas em questão por meio das contribuições em micro-escalas, aquelas que permitem olhar o usuário e os fenômenos de forma sistêmica à forma.
Táknræn eða raunveruleg þátttaka grunnskólabarna: Sýn barna á réttindi og lýðræðislega þátttöku í skóla
Authors: Björnsdóttir Elín Helga , Rúnarsdóttir Eyrún María , Kristinsdóttir Guðrún
Published: February 2023

Barnasáttmáli Sameinuðu þjóðanna er alþjóðlegur mannréttindasamningur sem snertir börn. Sáttmálinn felur í sér viðurkenningu á að börn þarfnist sérstakrar verndar umfram fullorðna og á að tryggja börnum vernd gegn ofbeldi, tækifæri og áhrifamátt. Fræðimenn telja að sá réttur barna sem eigi hvað mest undir högg að sækja varði lýðræðisákvæði hans. Meðal annars er algengt að ákvarðanir sem tengjast málefnum barna séu teknar án samráðs við þau. Síaukin áhersla er lögð á réttindi og þátttöku barna en til að tryggja réttindi þeirra í samræmi við sáttmálann er mikilvægt að allir; börn og fullorðnir, þekki til hans. Fyrir árið 2030 eiga öll sveitarfélög hér á landi að hafa hafið markvissa innleiðingu Barnasáttmálans og er ein leið til þess að nýta hugmyndafræði svonefnds réttindaskóla. Samkvæmt rannsóknum getur innleiðing sáttmálans haft jákvæð áhrif á skólastarf í heild sinni og aukið þekkingu barna á réttindum sínum. Markmið rannsóknarinnar er að varpa ljósi á reynslu og þekkingu barna á lýðræðislegri þátttöku og ávinning af fræðslu í skólum um Barnasáttmálann. Tekin voru rýnihópaviðtöl við 43 börn úr 4. og 8. bekk fjögurra skóla á Akureyri og í Eyjafjarðarsveit. Helstu niðurstöður sýna að þátttakendur virðast kunna skil á innihaldi þeirra réttinda sem Barnasáttmálinn veitir og er skilningur þeirra almennt góður. Börn í réttindaskóla höfðu fengið meiri fræðslu sem skilaði sér í auknum skilningi. Þrátt fyrir góða viðleitni í skólastarfi til að auka þátttöku nemenda í ákvörðunum virtist hún í sumum tilfellum einungis fela í sér táknræna þátttöku þeirra. Álykta má að fræðsla sé forsenda þess að innleiðing Barnasáttmálans njóti velgengni og er von okkar að þessi rannsókn stuðli að jákvæðara viðhorfi til skoðana og þátttöku barna.
Effect of botanical composition of free-range areas on production results and selected meat quality parameters of organic Yellowleg Partridge chickens
Authors: Sosnówka-Czajka Ewa , Skomorucha Iwona , Radkowska Iwona
Published: February 2023

The aim of the conducted research was to assess the impact of the botanical composition of free-range areas on the production results and selected quality parameters of the meat of fattening chickens of the Polish Yellowleg Partridge (Ż-33) breed in organic farming. Three hundred mixed-sex Ż-33 chicks were assigned to three groups: RP1 – free-range area with natural meadow vegetation, RP2 – free-range area sown with a mixture of plants containing ingredients stimulating growth, RP3 – free-range area sown with a mixture of plants rich in carotene. During the experiment, the production results (the weight of the birds, feed consumption, feed conversion ratio per g of weight gain, and mortality) were monitored. Observations were also performed on the behaviour in the free-range areas. On the 140th day of the experiment, a simplified slaughter analysis was carried out, the meat pH was measured, the colour of the muscles was also determined, as well as the water holding capacity and drip loss of the meat. In the meat samples, the content of nutrients and fatty acids was determined, and the peroxidizability index (PI) was calculated. Birds feeding in the RP2 free-range areas were characterised by higher body weight, better feed conversion, and higher dressing percentage compared to birds having access to the RP1 and RP3 free-range areas. On the other hand, the RP3 group Ż-33 chickens were characterised by a higher share of leg muscles and a tendency towards lower fat content in the carcass. It was also found that the meat of birds from the RP2 and RP3 groups was characterised by a higher pH24 compared to Ż-33 chickens from the RP1 group. Access to the RP2 free-range area modified the fatty acid profile, mainly in the leg muscles, reducing the palmitic acid and MUFA content and increasing the PUFA content. It can therefore be assumed that the plant species sown in the RP2 free-range area positively influenced the production results and the quality of the meat of fattening chickens feeding on them. It is therefore appropriate to carry out further studies on the type of vegetation sown in free-range areas in order to improve the efficiency and quality of the meat of organic fattening chickens.
Applying the CRISPR/Cas9 for Treating Human and Animal Diseases – Comprehensive Review
Authors: Abdelnour Sameh A. , Salaka Afnan S. , Shakoori Afnan M. , Alsaffar Nida , Hassanin Abdallah A. , Abukhalil Mohammad H. , Abd El-Hack Mohamed E.
Published: February 2023

Recently, genome editing tools have been extensively used in many biomedical sciences. The gene editing system is applied to modify the dnA sequences in the cellular system to comprehend their physiological response. A developing genome editing technology like clustered regularly short palindromic repeats (CRISPR) is widely used in medical sciences. CRISPR and CRISPR-associated protein 9 (CRISPR/Cas9) system is being exploited to edit any DNA mutations related to inherited ailments to investigate in animals (in vivo) and cell lines (in vitro). Remarkably, CRISPR/Cas9 could be employed to examine treatments of many human genetic diseases such as cystic fibrosis, tyrosinemia, phenylketonuria, muscular dystrophy, Parkinson’s disease, retinoschisis, hemophilia, β-thalassemia and atherosclerosis. Moreover, CRISPR/Cas9 was used for disease resistance such as tuberculosis, Johne’s diseases, chronic enteritis, and brucellosis in animals. Finally, this review discusses existing progress in treating hereditary diseases using CRISPR/Cas9 technology and the high points accompanying obstacles.