bluuebunny/crossref_metadata_2025 huggingface dataset:
Inoculation of fowlpox viruses coexpressing avian influenza H5 and chicken IL-15 cytokine gene stimulates diverse host immune responses
Authors: Mariatulqabtiah Abdul Razak , Nor Majid Nadzreeq , Giotis Efstathios S. , Omar Abdul Rahman , Skinner Michael A.
Published: June 2019

Fowlpox virus (FWPV) has been used as a recombinant vaccine vector to express antigens from several important avian pathogens. Attempts have been made to improve vaccine strains induced-host immune responses by coexpressing cytokines. This study describes the construction of recombinant FWPV (rFWPV) strain FP9 and immunological responses in specific-pathogen-free (SPF) chickens, co-expressing avian influenza virus (AIV) H5 of A/Chicken/Malaysia/5858/2004, and chicken IL-15 cytokine genes. Expression of H5 (50 kD) was confirmed by western blotting. Anti-H5 antibodies, which were measured by the haemagglutinin inhibition test, were at the highest levels at Week 3 post-inoculation in both rFWPV/H5- and rFWPV/H5/IL-15-vaccinated chickens, but decreased to undetectable levels from Week 5 onwards. CD3+/CD4+ or CD3+/CD8+T cell populations, assessed using flow cytometry, were significantly increased in both WT FP9- and rFWPV/H5-vaccinated chickens and were also higher than in rFWPV/H5/IL-15- vaccinated chickens, at Week 2. Gene expression analysis using real time quantitative polymerase chain reaction (qPCR) demonstrated upregulation of IL-15 expression in all vaccinated groups with rFWPV/H5/IL-15 having the highest fold change, at day 2 (117±51.53). Despite showing upregulation, fold change values of the IL-18 expression were below 1.00 for all vaccinated groups at day 2, 4 and 6. This study shows successful construction of rFWPV/H5 co-expressing IL-15, with modified immunogenicity upon inoculation into SPF chickens.
Pengelolaan Sistem Inventori Pada PT. Indomarco Pristama Menggunakan Analisis Economic Order Quantity
Authors: Suyono Bambang , Agustin Wirta , Efendi Yoyon
Published: June 2019

Persediaan menjadi masalah dalam PT. Indomarco Prismatama karena disebabkan pendataan masih bersifat manual dan hanya menggunakan aplikasi Microsoft Excel. Dalam rekapitulasi persedian stok membutuhkan waktu yang lama. Disamping itu sulit mengatur persedian akibatnya stok bisa mengalami kekurangan akan mengalami rugi dan kelebihan akan banyak barang yang disimpan. Maka diperlukan metode yang baik dan tepat dalam mengontrol persediaan (inventori). Salah satu metode yang dibuthkan adalah EOQ (Economic Order Quantity) diharapkan dapat membantu dalam menentukan dan mempertimbangkan pengendalian persediaan yang efektif. EOQ adalah kuantitas barang yang diperoleh dengan biaya minimal atau sering dikatakan sebagai jumlah pembelian optimal. Dengan adanya pengelolaan sistem inventori ini dapat mengetahui jumlah pesanan setiap waktu secara tepat. Akan meningkatkan layanan karena memberikan barang sesuai dengan keinginan konsumen sesuai dengan permintaan. Selain itu juga dapat menekan biaya penyimpan barang yang terlalu banyak akibat besarnya stok. Untuk pimpinan dapat mengambil keputusan secara baik dengan informasi yang valid dan akurat.
Rancang Bangun Aplikasi Pengelolaan Tugas Akhir dengan Menerapkan Prinsip-Prinsip Teknologi Mobile
Authors: Simatupang Julianto , Muhammad Muhammad
Published: June 2019

Pelaksanaan tugas akhir telah menjadi kegiatan tahunan bagi perguruan tinggi, bahkan dikampus-kampus besar hal ini telah menjadi kegiatan semesteran. Pengelolaan tugas akhir yang baik tentunya dengan dukungan teknologi yang tepat menjadi cita-cita bersama perguruan tinggi khususnya para pengelola program studi sebagai pelaksana akademik. Kendala yang dihadapi prodi manajemen informatika AMIK Mahaputra Riau saat ini adalah sulitnya mendapatkan informasi progress pelaksanaan tugas akhir dengan cepat dan tepat. Hal ini dikarenakan proses pengelolaan tugas akhir masih dilakukan dengan konvensional yaitu dengan menggunakan formulir dan dokumen persyaratan yang cukup banyak, serta pengajuannya sangat dibatasi oleh tempat/ruang dan waktu karena mahasiswa harus datang ke kampus untuk mengajukan judul tugas akhir. Dari keterbatasan dan kebutuhan informasi tersebut penelitian ini bertujuan untuk merancang aplikasi pengelolaan tugas akhir dengan menerapkan prinsip-prinsip mobile. Sehingga informasi dan pengajuan tugas dapat diakses dengan cepat, tepat dan akurat. Metodologi yang digunakan dalam penelitian ini adalah metode analisis dan perancangan. Hasil yang didapatkan dari penelitian ini adalah aplikasi pengajuan tugas akhir berbasis mobile yang dapat dimanfaatkan untuk mengajukan judul dan mengakses informasi pelaksanaan tugas akhir kapan saja dan dimana saja. Dengan aplikasi ini diharapkan mahasiswa dapat mengajukan tugas akhir dengan mudah dan cepat serta memperoleh informasi tugas akhir real-time.
Silindir Etrafındaki Kararsız Akışın Farklı Türbülans Modelleri ile Sayısal Olarak İncelenmesi
Authors: KARASU İlyas
Published: June 2019

Bu çalışmada, kritik altı olan 5000 Reynolds sayısında
silindir etrafındaki kararsız akış farklı türbülans modelleri ile sayısal
olarak incelenmiş ve bu modellerin performansları test edilmiştir. Çalışmada,
aynı şartlarda aynı ağ yapısında türbülans modelleri olarak LES, k-ω tabanlı
DES, k-ε Realizable ve k-kL-ω transition modelleri kullanılmıştır.
Benzeşimlerden elde edilen sayısal ortalama akış yapısı, sürükleme kuvvet
katsayısı ve Strouhal sayısı sonuçları, literatürden benzer şartlarda yapılan
bir deneysel çalışmanın sonuçlarıyla kıyaslanmıştır.  İncelenen parametreleri LES ve DES modelleri
düşük hata ile tahmin etmiştir. Diğer modellerden k-kL-ω transition
modeli sadece Strouhal sayısını iyi sonuç verirken, k-ε Realizable modeli akış
yapısını k-kL-ω transition modeline göre daha iyi verse de Strouhal
sayısı ve sürüklenme katsayısı değerini daha yüksek hata ile vermiştir.
APLIKASI LOCATION BASED SERVICE UNTUK INFORMASI KULINER DI YOGYAKARTA
Authors: Devie Erviana , Winarno Edy
Published: June 2019

Aplikasi Location Based Service (LBS) banyak dikembangkan karena mempunyai kemanfaatan yang sangat penting untuk berbagai hal, tak terkecuali untuk informasi kuliner. Dalam penelitian ini dibuat sebuah aplikasi kuliner dengan menggunakan metode location based service untuk mendapatkan suatu titik lokasi pada aplikasi, aplikasi yang dirancang untuk mempermudah pengguna mengunjungi berbagai macam kuliner saat berkunjung ke yogyakarta dengan menampilkan estimasi jarak dari posisi awal penggguna ke tempat tujuan.  Penelitian ini memanfaatkan global positioning system pada perangkat android. Pada perancangan ini digunakan rumus haversine untuk menghitung jarak tempuh pengguna dari posisi awal menuju lokasi tujuan secara manual. Hasil dari pengujian yang dilakukan pada salah satu data menunjukan selisih dari jarak tempuh sebanyak ±40km.
PERANCANGAN MODEL WATERFALL UNTUK SISTEM PENDUKUNG KEPUTUSAN MULTI ATTRIBUTE DENGAN METODE ANALYTIC NETWORK PROCESS
Authors: Cahyono Taufiq Dwi , Hadikurniawati Wiwien
Published: June 2019

Penelitian ini mengusulkan model waterfall yang digunakan dalam pembuatan sistem pendukung keputusan multi attribute dengan menggunakan metode Analytic Network Process (ANP). Model ini menyediakan kebutuhan pengguna dan kebutuhan perangkat lunak yang meliputi penganalisaan domain informasi, tingkah laku (behaviour), unjuk kerja (function) dan antarmuka. Penggunaan metode waterfall dapat menghasilkan perangkat lunak yang reliable dan bekerja secara efisien. Dari metode waterfall yang diusulkan dapat menghasilkan sebuah analisis kebutuhan atau persyaratan untuk menentukan atau memberikan gambaran umum bagi pengguna agar dapat membantu atau mendukung pencapaian sasaran pembuatan sistem yang meliputi kebutuhan data dan informasi, kebutuhan proses dan fungsi dan kebutuhan antarmuka atau interface.
SISTEM KENDALI TERPADU PERALATAN LISTRIK MENGGUNAKAN RASPBERRY PI BERBASIS JARINGAN KOMPUTER TOPOLOGI STAR
Authors: Budiarso Zuly , Nurraharjo Eddy
Published: June 2019

Perkembangan teknologi sistem dari sistem analog menjadi sistem digital merupakan salah satu hal yang menjadi awal berkembangnya sistem kendali didgital. Dengan berubahnya sistem kendali analog menjadi sistem kendali digital maka jenis perangkat yang digunakan untuk mengimplementasikan sistem kendali juga berbahjuga berubah. Mikrokontroler adalah salah perangkat yang berfungsi sebagai perangkat utama dalam sistem kendali digital.

Dengan mikrokontroler perancangan sistem kendali dapat dilakukan lebih efisien. Kemampuan mikrokontroler dalam sistem kendali dilengkapi dengan berbagai fitur penunjang, diantaranya prosessor, memory, A/D converter, analog/digital input/output dan beberapa kemampuan lain untuk mengolah data digital maupun analog.

Seiring dengan perkembangan teknologi di bidang komputer, perangkat sistem kendali juga semakin berkembang dari mikrokokontroler beralih ke komputer. Hal ini disebabkan kebutuhan perangkat yang dapat mendukung fungsi sistem kendali itu sendiri. Sistem kendali dituntut untuk dapat menyelesaikan berbagai permasalahan yang cukup rumit. Untuk dapat memenuhi kebutuhan sesuai dengan tuntutan keadaan maka personal komputer merupakan perangkat alternatif yang dapat digunakan sebagai pengganti mikrokontroler.

Raspberry Pi yang yang merpakan sebuah mini komputer Single Board Circuit merupakan pilihan yang dapat dilakukan auntuk menyelesaikan masalah sistem kendali. Secara umum spesifikasi teknis raspberry pi dapat mendukung sebuah sistem kendali dengan tingkat kesulitan tinggi. Fitur-fitur yang ada pada raspberry pi seperti memori, prosesor sudah dapat menyelesaikan masalah sistem kontrol. Perangkat I/O seperti USB, HDMI, dan kebutuhan daya yang kecil merupakan kelebihan dari raspberry. Selain itu raspberry juga dilengkapi dengan perangkat untuk komunikasis, yaitu Bluetooth dan wifi. Dengan demikian dapat dikatakan bahwa raspberry merupakan mini komputer yang dapat digunakan dalam sistem kendali.

Dengan menggunakan sebuah program, raspberry dapat digunakan untuk mengendalikan perangkat listrik seperti mematikan dan menghidupkan lampu dari jarak jauh, membuka dan menutup pintu, mengendalikan kamera dan berbagai macam peralatan listrik. Adanya bluetooth dan wifi memungkinkan raspberry dapat dioperasikan dari jarak jauh melalui jaringan internet atau jaringan komputer lokal.

Selain menggunakan perangkat nirkabel, raspbery juga dilengkapi dengan LAN Card. Sehingga untuk kemunikasi dengan raspbery dapat dilakukan melalui jaringan lokal. Dengan menggabungkan beberapa raspbery dalam sebuah jaringan lokal (LAN) terbentuklah sistem kendali berbasis jaringan komputer.
Tantangan Pengelolaan Perguruan Tinggi Pesantren yang Bermutu dalam Revolusi Industri Keempat
Authors: Taufiqur Rahman Taufiqur Rahman , Junaidi Junaidi
Published: June 2019

Higher education in Pesantren gain its competitive advantage through reputation of Pesantren. A development of the Higher Education is built on tradition of Pesantren which often contradict with modern trend. The goal to develop a quality higher education in Pesantren requires the institution to adjust with external environment about its concept and infrastructure. The adjustment is acted hierarcically from its quality policy to work instruction of day-to-day management.
PERUBAHAN PENGETAHUAN IBU HAMIL TENTANG KEKURANGAN ENERGI KRONIK PASCA PENYULUHAN
Authors: Ario Roekmy Prabarini
Published: June 2019

Chronic Energy Deficiency is a deficiency of energy and protein intake in pregnant women that lasted continuously and resulted in the occurrence of health problems. The purpose of this research was to get the Change of Knowledge of Pregnant Women About Chronic Energy Deficiency After Get the Counseling in Situbondo Health Center Area. The method in this research used pre experimental method (Preeksperimen) with one group pretest-postetest design. Research sampling technique used proportionate stratified random sampling with total population of 42 pregnant women. The data obtained is processed by Editing, Coding, and Tabulation. The instrument used in this study is a questionnaire. From the data analysis, it was known that the change of knowledge of pregnant mother before getting counseling is 2 (4,76%) pregnant woman with good knowledge while after getting counseling 38 (90,4%) pregnant mother with good knowledge. From result of this research can be concluded that The change of knowledge of pregnant women about chronic energy deficiency after getting counseling in Situbondo Health Care Area.

 Keywords : Knowledge, Counseling, Chronic Energy Deficiency.

ABSTRAK

 Kekurangan Energi Kronik (KEK) adalah kekurangan asupan energi dan protein pada Ibu hamil yang berlangsung secara terus menerus dan mengakibatkan timbulnya gangguan kesehatan. Adapun tujuan dari penelitian ini adalah untuk mendapatkan Perubahan Pengetahuan Ibu Hamil Tentang KEK (Kekurangan Energi Kronik) Pasca Mendapat Penyuluhan di Wilayah Puskesmas Situbondo. Metode pada penelitian ini metode praeksperimen (Preeksperimen) dengan rancangan one group pretest- postetest design’ . Tehnik sampling penelitian adalah proportionate starfied simple randem dengan jumlah populasi keseluruhan 42 ibu hamil. Data yang diperoleh diolah dengan Editing, Coding, dan Tabulasi. Instrumen yang digunakan pada penelitian ini adalah kuisioner. Dari hasil analisa data diketahui bahwa perubahan pengetahuan ibu hamil sebelum mendapat penyuluhan adalah 2 (4,76%) ibu hamil yang pengetahuan baik sedangakan setelah mendapat penyuluhan 38 (90,4%) ibu hamil yang pengetahuan baik.Dari hasil penelitian ini dapat disimpulkan bahwa adanya perubahan pengetahuan ibu hamil tentang KEK pasca mendapat penyuluhan di Wilayah Puskesmas Situbondo.

 Kata kunci : Pengetahuan, Penyuluhan, Kekurangan Energi Kronik
HUBUNGAN USIA IBU DENGAN KEJADIAN BERAT BAYI LAHIR RENDAH
Authors: Susilo Dwi Herman
Published: June 2019

Low birth weight is a baby born with less than 2500 grams of birth weight regardless of gestational weighing in 1 hour after birth. Low birth weight is still the cause of mortality (death) and morality (pain) during neonatal period (infants aged 0 - 28 days). Research design used was cross sectional approach. With the population of all babies born in the work area of ​​puskesmas banyuputih of Situbondo district as many as 818 babies, Sample in this study as many as 164 babies with the sampling method using proportionate atratifed random technique. Technique of taking data with medical record, executed in May 2015. Processing and data analysis using statistic test that was contingency coefficient test with level maximize α <0,05. The results showed that the results obtained p value = 0.00 which means there is a significant correlation of the mother age with low birth weight n the work area of ​​puskesmas banyuputih Situbondo regency. 

Keywords : Mother Age, Low Birth Weight

 

ABSTRAK

Berat bayi lahir rendah adalah bayi yang lahir dengan berat lahir kurang dari 2500 gr tanpa memandang masa gestasi yang di timbang dalam 1 jam setelah lahir. Berat bayi lahir rendah sampai saat ini masih merupakan penyebab mortalitas (kematian) dan morbilitas (kesakitan) pada masa neonatal (bayi umur 0 – 28 hari). Desain penelitian yang digunakan adalah pendekatan cross sectional. Dengan populasi semua bayi yang lahir di wilayah kerja puskesmas banyuputih kabupaten situbondo sebanyak 818 bayi, sampel penelitian sebanyak 164 bayi dengan dengan metode sampling menggunakan teknik proportionate atratifed random. Teknik pengambilan data dengan medical record, dilaksanakan pada bulan Mei 2015. Pengolahan dan analisa data menggunakan uji statistic yaitu uji koefesien contingensi dengan tingkat kemaksimalan α <0,05. Hasil penelitian menunjukkan bahwa diperoleh hasil nilai p= 0,00 yang artinya ada hubungan yang signifikan antara Usia ibu dengan berat bayi lahir rendah di wilayah kerja puskesmas banyuputih Kabupaten Situbondo.

Kata Kunci : Usia Ibu, Berat Bayi Lahir Rendah
FREKUENSI PENGGUNAAN GADGET TERHADAP PERKEMBANGAN SOSIAL DAN KEMANDIRIAN PADA ANAK USIA 3-5 TAHUN
Authors: Umiyah Astik , Lukitasari Shovi
Published: June 2019

Golden age or golden period is the term for children aged 0-5 years. At this time almost all have time used to play because playing is fun activity and inherent needs for every children. Before appeared gadget as new game alternative media for children, children have been know about traditional games, but appeared gadget, children more often used gadget to play new games in gadget. This has a negative impact on the optimization of children. This research aims was to understand the influence of the frequency of gadgets use on social development and independence children aged 3 to 5 years. The research design was used cross sectional. Population in this study amount 175 children, with sample amount 63 children were taken used simple random sampling . From the data that has been tested using spearman rank obtained the ? value = 0.48 > 0,05, then H0 is received . So that there isn’n influence of frequence of gadgets use on social development and independence in children aged 3 to 5 years.

Keywords : Golden Age , Gadgets, Development.

ABSTRAK

Golden age atau periode emas merupakan istilah bagi anak berusia 0-5 tahun. Pada masa ini hampir seluruh waktu yang dimiliki digunakan untuk bermain, karena bermain merupakan suatu aktivitas menyenangkan serta kebutuhan yang sudah melekat pada setiap anak. Permainan tradisional lebih dulu dikenal sebelum adanya gadget, yang sekarang gadget menjadi permainan alternative pada era saat ini. Keberadaan gadget, menjadikan ketertarikan anak menikmati sensasi permainan baru di dalam gadget. Hal ini menghambat optimalisasi anak. Tujuan penelitian ini mengetahui pengaruh penggunaan frekuensi gadget terhadap perkembangan sosial dan kemandirian pada anak usia 3-5 tahun. Penelitian ini menggunakan desain cross secsional. Populasi sebanyak 175 anak, dengan sampel sebanyak 63 anak dengan tehnik menggunakan simple random sampling. Data setelah diuji menggunakan spearman rank diperoleh nilai ? value = 0.48 > 0,05 maka H0 diterima, sehinnga tidak terdapat pengaruh penggunaan frekuensi gadget terhadap perkembangan sosial dan kemandirian pada anak usia 3-5 tahun.

Kata kunci      : Golden Age, Gadget, Perkembangan.
MANFAAT BERENANG DAN TERAPI AIR PADA PERTUMBUHAN DAN PERKEMBANGAN BAYI & BALITA
Authors: Rufaindah Ervin
Published: June 2019

Growth and development has increased rapidly at an early age, ie from 0-5 years. The period of child development during infancy is a basic growth that will influence and determine the development of language skills, creativity, social awareness, emotional and intelligence that goes quickly and is the foundation of the next development. As many as 16% of children under five in Indonesia experience developmental disorders, both smooth and rough motor development, hearing loss, lack of intelligence and delays. The method used was literature review study which includes systematic search of computerized database: EBSCOHOST, Google Scholar and Pubmed in the form of research journal totaling 10 journals published since 2010-2014. 10 journals using quantitative methods. This literature study tried to explain about the activities in the water such as swimming and water therapy for the growth and development of infants. The result showed that swimming or other aquatic activities can improve gross motor skills, fine motor skills and language skills in toddlers. Swimming and water therapy in toddler can be beneficial to support the growth and development of  baby and toddler.

 Keywords : Swimming, Water Therapy, Growth And Development, Baby And Toddler

ABSTRAK

 Pertumbuhan dan perkembangan mengalami peningkatan yang pesat pada usia dini, yaitu dari 0-5 tahun. Periode tumbuh kembang anak pada masa balita merupakan pertumbuhan dasar yang akan mempengaruhi dan menentukan perkembangan kemampuan berbahasa, kreatifitas, kesadaran sosial, emosional dan intelegensia yang berjalan dengan cepat serta merupakan landasan perkembangan berikutnya. Sebanyak 16% balita di Indonesia  mengalami  gangguan  perkembangan, baik  perkembangan  motorik  halus  dan  kasar,  gangguan  pendengaran,  kecerdasan  kurang  dan  keterlambatan. Metode yang digunakan adalah  studi tinjauan literatur (literature review) meliputi studi pencarian sistematis database terkomputerisasi: EBSCOHOST, Google Scholar dan Pubmed  dalam bentuk jurnal penelitian berjumlah 10 jurnal yang diterbitkan sejak tahun 2010-2014. 10 jurnal menggunakan metode kuantitatif. Studi literatur ini mencoba memaparkan tentang aktifitas di air seperti berenang dan terapi air untuk pertumbuhan dan perkembangan bayi balita. Hasil mneunjukkan berenang atau aktifitas air lainnya dapat meningkatkan kemampuan motorik kasar, motorik halus dan kemampuan bahasa pada balita. Berenang dan terapi air pada balita dapat bermanfaat untuk mendukung pertumbuhan dan perkembangan bayi dan balita.

Kata Kunci: Berenang, Terapi Air, Pertumbuhan Dan Perkembangan, Bayi Dan Balita
INTENSITAS NYERI DISMENORHEA PRIMER SEBELUM DAN SESUDAH DILAKUKAN TERAPI SPIRITUAL EMOTIONAL FREEDOM TECHNIQUE
Authors: Hamidiyah Azizatul , Jannah Fevi Mila Nur
Published: June 2019

Spiritual Emosional Freedom Technique is a non pharmacologic therapy to decrease woman menstruation pain. Based on prelimenery study about dysmenorrhea which did in ten Ibrahimy midwifery academy students showed that amount 4 people (40%) had low pain 2, people (20%) had middle pain, and found 4 people (40%) had not dysmenorrhea every month. The objective of this research was to know difference primary dysmenorrhea pain intensity before and after SEFT therapy for Ibrahimy midwifery academy student of sukorejo situbondo year 2017. Design of this research used pre-experimental. The population in this research were ibrahimy midwifery academy students who had dysmenorrhea and menstruation experienced in the third week of August 2017, amounts 21 people. Sample of this research used total sampling. Data was collected using questionnaires and checklist. Data analyzed using Wilcoxon Signed Rink Test with maximum level a = 0.05, the result showed that the p < a was 0,000 then H0 rejected, it mean there was differences primary dysmenorrhea pain before and after SEFT therapy.

 Keywords: Dysmenorrhea, Spiritual Emosional Freedom Technique, Pain Scale

ABSTRAK

 Spiritual Emotional Freedom Technique (SEFT) adalah tindakan non farmakologis yang memiliki manfaat untuk mengurangi nyeri haid pada wanita. Berdasarkan studi pendahuluan tentang dismenorhea yang dilakukan pada 10 Mahasiswa Akbid Ibrahimy didapatkan sebanyak 4 orang (40%) mengalami nyeri ringan, 2 orang (20%) mengalami nyeri sedang, dan sisanya tidak mengalami dismenorhea setiap bulan. Tujuan penelitian ini yaitu untuk mengetahui perbedaan intensitas nyeri dismenorhea primer sebelum dan sesudah dilakukan terapi SEFT Pada Mahasiswa Akbid Ibrahimy Sukorejo Situbondo Tahun 2017. Desain penelitian yang digunakan adalah pra-experimental. Populasi penelitian ini adalah Mahasiswa Akbid Ibrahimy yang dismenorhea dan menstruasi pada minggu ketiga pada bulan Agustus 2017, sebanyak 21 orang. sampel dalam penelitian ini menggunakan total sampling. Pengumpulan data menggunakan kuesioner dan checklist. Analisa data menggunakan uji Wilcoxon Signed Rink Test dengan tingkat kemaksimalan a = 0,05. Hasil uji menunjukkan p < a yaitu 0,000 maka H0 ditolak, artinya ada perbedaan intensitas nyeri dismenorhea primer sebelum dan sesudah dilakukan terapi SEFT .

 Kata kunci : Dismenorhea, Spiritual Emotional Freedom Technique, Skala Nyeri
ANALYSIS OF DETERMINANTS OF THE PROFESSIONAL COMPETENCES OF TOURISM EMPLOYEES IN BAC LIEU PROVINCE
Authors: Huynh Huy Truong , Nguyen Duy Kien
Published: June 2019

Human resource plays one of the important elements in developing an enterprise and the economy. This study aims to empirically analyse the determinants of professional competences of the employees working in the tourism industry in Bac Lieu province based on three criteria: knowledge, skills and attitude. The results from the survey of 183 tourists and 43 employees at the selected tourism sites in Bac Lieu province have showed that the employees’ competencehas to be associated with professional knowledge and tourist-related services. Besides regarding attitude factor, employees have to be professional, honest, and friendly. These determinants have not only shown the professional competences of employees, but also influenced to the servicerelated quality in this industry.
SPECIES COMPOSITION AND HABITAT OF INSECTS AT LUNG NGOC HOANG NATURAL PRESERVATION AREA IN HAU GIANG PROVINCE
Authors: Truong Dan Hoang , Tran Lien Thi Bich , Bui Tho Truong
Published: June 2019

The survey is carried out at Lung Ngoc Hoang Natural Preservation area in Hau Giang province from May 2016 to May 2017 in four different habitats: habitat of agriculture, habitat of agro-forestry, habitat of Melaleuca forest and habitat of water with 35 sampling stations. The method of using the landing net to collect  specimens was used in this research.  The study result showed that there were 100 insect species belonging to 80 genera of 29 families in 9 Orders. They were characterized by high dominance index and frequency of appearance. Amongst the surveyed species, Oecophylla smaragdina and Dolichodorus thoracicus hadthe highest frequency of appearance in both wet and dry seasons. The findings also indicated that Coastal dike was the most diverse habitat of species  composition as well as the number of individual insects, which were found in both seasons.
FEATURES OF GODDESS WORSHIP IN SA DEC, DONG THAP PROVINCE
Authors: Duong Tung Thanh
Published: June 2019

The paper presents the goddess worship in Sa Dec city, Dong Thap province, which is presented in four main goddess cults: The Lady of the Realm, Thien Hau Goddess, the Five Elements deities and Co Hy Goddess. Beside the common characteristics shared widely among goddess worship nationwide, the goddess beliefs in Sa Dec have strongly expressed two outstanding characteristics: hybridity and tolerance. Therefore, the preservation and promotion of the values of goddess beliefs in the context of global integration are currently becoming necessary and meaningful tasks for both governmental agents  and public communities.
BIOMASS OF WILD RICE (Oryza rufipogon) AT TRAM CHIM NATIONAL PARK, DONG THAP PROVINCE
Authors: Le Thang Trong , Truong Dan Hoang , Bui My Thi Yen , Lam Tuan Hoang
Published: June 2019

This study was carried out to evaluate the status of Wild Rice (Oryza rufipogon) biomass at Tram Chim National Park, Dong Thapprovince for the preservation of biomes and forest fire prevention. The samples had been collected  by randomly design with 9 standard plots and each standard plot contains 3 subplots with 1m × 1m in size. The characteristics were assessed including mass, height, water levels and biomass of Wild Rice at each plot. The results showed that the Wild Rice community appeared in 27 samling plots with a total area of 697.8 ha in which the lowest and highest areas of Wild Rice were respectively 1.3 ha and 162.3 ha. In addition, the fresh and dry biomass in each community were 44.85±23.1 tonnes/ha and 9.24±3.37 tonnes/ha, respectively. The relationship between water depth and vegetation active-layer thickness were closely correlated (r = 0.71).
Cooperación para el desarrollo social en el posconflicto colombiano. Una mirada desde las necesidades psicosociales de la población infantil
Authors: Acevedo Correa Yesenia , Gómez Molina Sergio , Alvarán López Sandra Milena , Valencia Arias Alejandro
Published: June 2019

El conflicto armado de larga duración, resistido por la población colombiana durante más de cinco décadas, generó afectaciones psicosociales significativas en las poblaciones. El acuerdo de paz es un paso fundamental, sin embargo, no es suficiente. Se requieren ejercicios que involucren con mayor protagonismo a las poblaciones; la construcción de la paz debe hacerse desde y para las regiones, permitiendo así la reconstrucción colectiva del tejido social, a través de intervenciones psicosociales contextualizadas. La salud mental de la población ha sido afectada considerablemente, y la naturalización de la guerra es una de las consecuencias de más impacto en el conflicto, ya que la violencia se instauró como mecanismo mediador de relaciones sociales. El presente artículo tiene como objetivo presentar una propuesta de análisis e intervención psicosocial, para la promoción de la resiliencia en la infancia y el desarrollo de procesos terapéuticos alternativos para adultos, desde perspectivas de rehabilitación emocional, con el fin de propiciar entornos generadores de paz.
ENHANCEMENT OF RESEARCH METHOD FOR SPATIAL LOCATION OFTEMPOROMANDIBULAR ELEMENTS AND MAXILLARY AND MANDIBULAR MEDIALINCI
Authors: Gladilin Yury , Fomin Igor , Domenyuk Dmitry , Kondratyuk Andrey , Subbotin Roman
Published: June 2019

This work reveals the analysis outcomes
for craniometric and morphometric parameters of
the temporomandibular joints and incisal dentofacial
segments obtained through studying 157 computer
tomograms and lateral skull teleradiographies from
people with physiological occlusion of permanent teeth
in the first mature age period. Detailed investigation of
the spatial arrangement of the craniofacial structures
allowed developing, substantiating and testing a method
of computer tomograms combination of the mandibular
joint and dentofacial segments of the mandibular and
maxillary medial incisors with head teleradiographies in
the lateral projection. This algorithm allowed increasing
the measurements reliability (linear, angular) in the
sagittal plane, identifying the degree of complexity and
justifying the choice of tactics for the planned treatment,
describing the facial skull growth type (horizontal, vertical
and neutral), as well as evaluating the effectiveness of
orthodontic treatment at all stages.
PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL CHANGES IN CHERNOBYL LIQUIDATORS LIVING IN HIGH ALTITUDE CONDITIONS
Authors: Khachatryan Gayane , Karapetyan Anahit
Published: June 2019

It is known that the human body living in conditions of high mountains is under the constant exposure
of the environmental factors, and, in case of prolonged
exposure, these factors affect the physiological functions of the body, which in many cases leads to adaptation to the given conditions. Climatic factors, such as
reduced atmospheric pressure, reduced oxygen partial
pressure, temperature, humidity, high intensity of solar
radiation, air ionization and other factors, affect the
human body through the skin, lungs, sensory organs,
causing different physiological shifts.
The aim of the presented study has been to reveal
the differences in morbidity, changes in the functional
status of different organs and systems in liquidators
living on the plains compared with the residents of the
highland regions of Armenia.
SPECIFIC FEATURES OF MAJOR ANGULAR PARAMETERS OF CRANIO-FACIAL COMPLEX IN MALES AND FEMALES WITH MESIAL OCCLUSION IN THEIR FIRST MATURE A
Authors: Muzurova Lyudmila , Anisimova Elena , Fomkina Olga , Gladilin Yury , Zaychenko Alexander , Zagorovskaya Tatyana , Khairullin Radik , Konnov Valeriy
Published: June 2019

Uneven growth, leading to an abnormal ratio of
the upper and lower jaws, underlies the development
of various occlusion issues . The respective
literature holds it that the dental anomalies variability
in different areas ranges from 11% to 90%. The high
prevalence of occlusion issues should be attributed
primarily to the difficulty associated with their correct
and timely diagnostics . The research carried
out to identify occlusion anomalies reveal the lack of
a decrease trend, which means there are stable mechanisms triggering the development of this pathology,
which keep its prevalence at a stable level .
Besides, this pathology is complicated with occlusive
and musculo-articular disorders .
ŠEŠĖLINĘ EKONOMIKĄ LEMIANČIŲ VEIKSNIŲ TYRIMAS / FACTORS THAT DETERMINE SHADOW ECONOMY IN LITHUANIA AND EUROPE
Authors: Kazimieraitytė Miglė , Skvarciany Viktorija
Published: June 2019

The problem of the shadow economy exists in the majority of countries and, depending on its scale, affects the economic development of the state, the social well­being of companies and the population and the country’s policy. This economy distorts competition, has a negative impact on the country’s tax system and its structure and the distribution of state revenue becomes unregulated and distorted. This economic activity alters official statistics so a policy based on it can become simply irrational and ineffective. All this leads to a change in government­funded general budget revenue and slows down the country’s economic growth. The purpose of this article is to identify and evaluate the factors that influence the shadow economy in Lithuania and across Europe. Objectives: to analyse the factors influencing the shadow economy after the analysis of the scientific literature, to develop a methodology that will be used for the assessment of the shadow economy factors, based on the presented methodology prepare calculations about the estimation of shadow economy factors. The following methods were used for the research: analysis of scientific literature, correlation, pair regression and multiple regression analysis. The results have shown that average salary, levels of poverty and corruption in the country, compulsory taxes and inflation have the greatest impact on the country’s shadow economy.
Evolution of the Gas Mass Fraction of Progenitors to Today’s Massive Galaxies: ALMA Observations in the CANDELS GOODS-S Field
Authors: Wiklind Tommy , Ferguson Henry C. , Guo Yicheng , Koo David C. , Kocevski Dale , Mobasher Bahram , Brammer Gabriel B. , Kassin Susan , Koekemoer Anton M. , Giavalisco Mauro , Papovich Casey , Ravindranath Swara , Faber Sandra M. , Freundlich Jonathan , de Mello Duilia F.
Published: June 2019

We present an Atacama Large Millimeter/submillimeter Array (ALMA) survey of dust continuum emission in a sample of 70 galaxies in the redshift range z = 2–5 selected from the CANDELS GOODS-S field. Multi-epoch abundance matching (MEAM) is used to define potential progenitors of a z = 0 galaxy of stellar mass 1.5 × 1011
M
⊙. Gas masses are derived from the 850 μm luminosity. Ancillary data from the CANDELS GOODS-S survey are used to derive the gas mass fractions. The results at z ≲ 3 are mostly in accord with expectations: The detection rates are 75% for the z = 2 redshift bin, 50% for the z = 3 bin, and 0% for z ≳ 4. The average gas mass fraction for the detected z = 2 galaxies is f
gas = 0.55 ± 0.12 and f
gas = 0.62 ± 0.15 for the z = 3 sample. This agrees with expectations for galaxies on the star-forming main sequence, and shows that gas fractions have decreased at a roughly constant rate from z = 3 to z = 0. Stacked images of the galaxies not detected with ALMA give upper limits to f
gas of <0.08 and <0.15, for the z = 2 and z = 3 redshift bins. None of our galaxies in the z = 4 and z = 5 sample are detected, and the upper limit from stacked images, corrected for low metallicity, is f
gas < 0.66. We do not think that lower gas-phase metallicities can entirely explain the lower dust luminosities. We briefly consider the possibility of accretion of very low-metallicity gas to explain the absence of detectable dust emission in our galaxies at z ≳ 4.
Search for Nearby Earth Analogs. I. 15 Planet Candidates Found in PFS Data*
Authors: Feng Fabo , Crane Jeffrey D. , Wang Sharon Xuesong , Teske Johanna K. , Shectman Stephen A. , Díaz Matías R. , Thompson Ian B. , Jones Hugh R. A. , Butler R. Paul
Published: June 2019

The radial velocity (RV) method plays a major role in the discovery of nearby exoplanets. To efficiently find planet candidates from the data obtained in high-precision RV surveys, we apply a signal diagnostic framework to detect RV signals that are statistically significant, consistent in time, robust in the choice of noise models, and do not correlated with stellar activity. Based on the application of this approach to the survey data of the Planet Finder Spectrograph, we report 15 planet candidates located in 14 stellar systems. We find that the orbits of the planet candidates around HD 210193, 103949, 8326, and 71135 are consistent with temperate zones around these stars (where liquid water could exist on the surface). With periods of 7.76 and 15.14 days, respectively, the planet candidates around star HIP 54373 form a 1:2 resonance system. These discoveries demonstrate the feasibility of automated detection of exoplanets from large RV surveys, which may provide a complete sample of nearby Earth analogs.
Bacillus coagulans and its applications in medicine
Authors: Mu Y. , Cong Y.
Published: June 2019

Bacillus coagulans is a probiotic bacterium that produces spores. Due to its excellent stability, it has been widely used in medicine, food and chemical industry. Recent studies have shown that B. coagulans has therapeutic effects on intestinal diseases, such as acute diarrhoea, irritable bowel syndrome, antibiotic-related diarrhoea, constipation and colitis via modulation of the microbiota composition, host immunity and metabolism. Additionally, toxicological experiments and a large number of clinical observations have showed that B. coagulans is safe and has no effect of mutagenicity, teratogenicity or genotoxicity. This review summarises the latest advances associated with B. coagulans, from its biological features, probable action mechanisms, toxicity, and medical applications.
Spatial mismatch, education and language skills in the Brussels metropolis: an analysis
Authors: Theys Tobias , Deschacht Nick , Adriaensens Stef , Verhaest Dieter
Published: June 2019

Spatial mismatch, where job seekers do not live where jobs can be found, can be an important barrier on the labour market, especially for vulnerable groups. In this study we look at the role that spatial mismatch plays in the Brussels metropolis. Using an improved benchmark, the distance-weighted spatial mismatch index, that also considers location-driven mismatch, we compare the spatial mismatch between the high- and low-skilled labour market and the labour market for the low-skilled with and without language skills. In the largest possible definition of the Brussels metropolis, results show a spatial mismatch of up to 50 % larger for the low-skilled, in comparison with the high-skilled. For the low-skilled without language skills, the spatial mismatch is 115 % higher than for the low-skilled with language skills. This difference is mainly due to a relative surplus of low-skilled job seekers (without language skills) in the Brussels-Capital Region and a relative shortage in the first belt of municipalities around the Region.
The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function
Authors: Hernandez-Mir Gerard , Raphael Itay , Revu Shankar , Poholek Catherine H. , Avery Lyndsay , Hawse William F. , Kane Lawrence P. , McGeachy Mandy J.
Published: June 2019

β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is best known for its role in Alzheimer's disease amyloid plaque formation but also contributes to neurodegenerative processes triggered by CNS injury. In this article, we report that BACE1 is expressed in murine CD4+ T cells and regulates signaling through the TCR. BACE1-deficient T cells have reduced IL-17A expression under Th17 conditions and reduced CD73 expression in Th17 and inducible T regulatory cells. However, induction of the Th17 and T regulatory transcription factors RORγt and Foxp3 was unaffected. BACE1-deficient T cells showed impaired pathogenic function in experimental autoimmune encephalomyelitis. These data identify BACE1 as a novel regulator of T cell signaling pathways that impact autoimmune inflammatory T cell function.
Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-α
Authors: Vasquez Marcos , Consuegra-Fernández Marta , Aranda Fernando , Jimenez Aitor , Tenesaca Shirley , Fernandez-Sendin Myriam , Gomar Celia , Ardaiz Nuria , Di Trani Claudia Augusta , Casares Noelia , Lasarte Juan Jose , Lozano Francisco , Berraondo Pedro
Published: June 2019

Multiple sclerosis (MS) is a chronic autoimmune disease with no curative treatment. The immune regulatory properties of type I IFNs have led to the approval of IFN-β for the treatment of relapsing-remitting MS. However, there is still an unmet need to improve the tolerability and efficacy of this therapy. In this work, we evaluated the sustained delivery of IFN-α1, either alone or fused to apolipoprotein A-1 by means of an adeno-associated viral (AAV) system in the mouse model of myelin oligodendrocyte glycoprotein–induced experimental autoimmune encephalomyelitis. These in vivo experiments demonstrated the prophylactic and therapeutic efficacy of the AAV–IFN-α or AAV–IFN-α fused to apolipoprotein A-1 vectors in experimental autoimmune encephalomyelitis, even at low doses devoid of hematological or neurologic toxicity. The sustained delivery of such low-dose IFN-α resulted in immunomodulatory effects, consisting of proinflammatory monocyte and T regulatory cell expansion. Moreover, encephalitogenic T lymphocytes from IFN-α–treated mice re-exposed to the myelin oligodendrocyte glycoprotein peptide in vitro showed a reduced proliferative response and cytokine (IL-17A and IFN-γ) production, in addition to upregulation of immunosuppressive molecules, such as IL-10, IDO, or PD-1. In conclusion, the results of the present work support the potential of sustained delivery of low-dose IFN-α for the treatment of MS and likely other T cell–dependent chronic autoimmune disorders.
Density of positive Lyapunov exponents for symplectic cocycles
Authors: Xu Disheng
Published: June 2019

We prove that Sp

(2d,\mathbb R)

-cocycles, HSp(

2d

)-cocycles and pseudo-unitary cocycles with at least one non-zero Lyapunov exponent are dense in all usual regularity classes for non periodic dynamical systems. For Schrödinger operator on the strip, we prove a similar result for density of positive Lyapunov exponents. This generalizes a result of A. Avila [2] to higher dimensions.
Spatiotemporal variability of shortwave radiation introduced by
clouds over the Arctic sea ice
Authors: Barrientos Velasco Carola , Deneke Hartwig , Griesche Hannes , Seifert Patric , Engelmann Ronny , Macke Andreas
Published: June 2019

Abstract. The role of clouds in recent Arctic warming is not fully understood, including their effects on the shortwave radiation and the surface energy budget. To investigate relevant small-scale processes in detail, an intensive field campaign was conducted during early summer in the central Arctic during the Physical feedbacks of Arctic planetary boundary layer, Sea ice, Cloud and AerosoL (PASCAL) drifting ice floe station. During this campaign, the small-scale spatiotemporal variability of global irradiance was observed for the first time on an ice floe with a dense network of autonomous pyranometers. 15 stations were deployed covering an area of 0.83 km × 1.3 km from June 4–16, 2017. This unique, open-access dataset is described here, and an analysis of the spatiotemporal variability deduced from this dataset is presented for different synoptic conditions. Based on additional observations, 5 typical sky conditions were identified and used to determine the values of the mean and variance of atmospheric global transmittance for these conditions. Overcast conditions were observed 39.6 % of the time predominantly during the first week, with an overall mean transmittance of 0.47. The second-most frequent conditions corresponded to multi-layer clouds (32.4 %) which prevailed in particular during the second week, with a mean transmittance of 0.43. Broken clouds had a mean transmittance of 0.61 and a frequency of occurrence of 22.1 %. Finally, the least frequent sky conditions were thin clouds and cloudless conditions, which both had a mean transmittance of 0.76, and occurrence frequencies of 3.5 % and 2.4 %, respectively. For overcast conditions, lower global irradiance was observed for stations closer to the ice edge, likely attributable to the low surface albedo of dark open water, and a resulting reduction of multiple reflections between the surface and cloud base. Using a wavelet-based multi-resolution analysis, power spectra of the time-series of atmospheric transmittance were compared for single-station and spatially averaged observations, and for different sky conditions. It is shown that both the absolute magnitude and the scale-dependence of variability contains characteristic features for the different sky conditions.
A conservation palaeobiological approach to assess faunal response of threatened biota under natural and anthropogenic environmental change
Authors: van de Velde Sabrina , Jorissen Elisabeth L. , Neubauer Thomas A. , Radan Silviu , Pavel Ana Bianca , Stoica Marius , Van Baak Christiaan G. C. , Martínez Gándara Alberto , Popa Luis , de Stigter Henko , Abels Hemmo A. , Krijgsman Wout , Wesselingh Frank P.
Published: June 2019

Abstract. Palaeoecological records are required to test ecological
hypotheses necessary for conservation strategies as short-term observations
can insufficiently capture natural variability and identify drivers of
biotic change. Here, we demonstrate the importance of an integrated
conservation palaeobiology approach when making validated decisions for
conservation and mitigating action. Our model system is the Razim–Sinoie
lake complex (RSL) in the Danube Delta (Black Sea coast, Romania), a dynamic
coastal lake system hosting unique Pontocaspian mollusc species that are now
severely under threat. The Pontocaspians refer to an endemic species group
that evolved in the Black Sea and Caspian Sea basins under reduced salinity
settings over the past few million years. The natural, pre-industrial RSL
contained a salinity gradient from fresh to mesohaline (18 ppm) until human
intervention reduced the inflow of mesohaline Black Sea water into the lake
system. We reconstruct the evolution of the RSL over the past 2000 years
from integrated sedimentary facies and faunal analyses based on 11 age-dated
sediment cores and investigate the response of mollusc species and
communities to those past environmental changes. Three species associations
(“marine”, “Pontocaspian” and “freshwater”) exist and their spatio-temporal
shifts through the system are documented. Variable salinity gradients
developed, with marine settings (and faunas) dominating in the southern part
of the system and freshwater conditions (and faunas) in the northern and
western parts. Pontocaspian species have mostly occurred in the centre of
the RSL within the marine–freshwater salinity gradient. Today, freshwater
species dominate the entire system, and only a single Pontocaspian species
(Monodacna colorata) is found alive. We show that the human-induced reduced marine influence
in the system has been a major driver of the decline of the endemic
Pontocaspian biota. It urges improved conservation action by
re-establishing a salinity gradient in the lake system to preserve these
unique species.