bluuebunny/crossref_metadata_2025 huggingface dataset:
Blood markers of fibrinolysis system and vascular wall state in neonates born to mothers with preeclampsia
Authors: Попова И.Г. , Назаров С.Б. , Ситникова О.Г. , Кузьменко Г.Н. , Клычева М.М. , Харламова Н.В. , Парейшвили В.В.
Published: May 2021

Введение. Новорожденные, родившиеся у матерей с патологией во время беременности, составляют группу высокого риска тромботических и геморрагических осложнений, которые повышаются при наличии у новорожденных перинатальной патологии. Цель исследования: оценить показатели, характеризующие состояние системы фибринолиза и сосудистой стенки в крови новорожденных, родившихся у матерей с преэклампсией (ПЭ), для прогнозирования риска тромботических и геморрагических осложнений у таких детей. Материалы и методы. Обследовано 60 новорожденных, родившихся у матерей с ПЭ. Контрольную группу составили 30 новорожденных от матерей без ПЭ. Исследовали венозную кровь, взятую у новорожденных на 3–5-е сутки жизни. В крови определяли уровень тканевого активатора плазминогена (t-РА), ингибитора тканевого активатора плазминогена (PAI-1) и тромбомодулина. Результаты. Выявлено, что у новорожденных от матерей с ПЭ на 3–5-е сутки жизни отмечаются признаки повреждения эндотелия и повышение фибринолитической активности крови, на что указывает повышение содержания t-РА, PAI-1 и тромбомодулина в крови. Заключение. Полученные данные свидетельствуют о риске развития геморрагических осложнений у таких детей.

Background. Neonates born to mothers with pathology during pregnancy are at high risk of thrombotic and hemorrhagic complications that are increased if neonates have perinatal pathology. Objectives: to assess blood parameters characterizing fibrinolysis and vascular wall of neonates born to mothers with preeclampsia (РЕ), to predict the risk of hemorrhagic complications in these children. Patients/Methods. 60 neonates born to mothers with РЕ were examined. The control group consisted of 30 neonates born to mothers without РЕ. We studied levels of tissue plasminogen activator (t-PA), inhibitor of tissue plasminogen activator (PAI-1) and thrombomodulin (TM) in venous blood taken from neonates on the 3–5th days of life. Results. In neonates born to mothers with PE we revealed on the 3–5th days of life increased blood levels of t-PA, PAI-1 and TM that characterized endothelial damage and increased blood fibrinolytic activity. Conclusions. The data obtained indicate the risk of hemorrhagic complications development in these children.
Investigating the Inhibition Effect of Portulaca oleracea against SARS-CoV-2 through Molecular Docking Simulation
Authors:   Computational Chemistry Group, Egyptian Petroleum Research Institute, Egypt, AN El-Hoshoudy , EG Zaki ,   Computational Chemistry Group, Egyptian Petroleum Research Institute, Egypt, SM Elsaeed ,   Computational Chemistry Group, Egyptian Petroleum Research Institute, Egypt
Published: May 2021

Recently a new virus strain designated as SARS coronavirus result in a fatal pandemic known as COVID-19. Bioinformatics and drug screening are directed for the assessment of potential inhibitors before their clinical implementation for the treatment of this fatal pneumonia. One of the expected natural potent inhibitors is Portulaca oleracea which has been assigned as an effective drug to different human ailments throughout the whole world. P. oleracea is widely spread in most areas of Egypt. In the current study, hydrophilic polysaccharides were purified from Portulaca oleracea extracts. Molecular docking simulation is implemented to investigate the antiviral effect of the purified polysaccharides to inhibit COVID-19. The viral protease was downloaded from a Protein Data Bank (PDB# 6y84) then docked with the potent inhibitors. The docking results indicate that the purified polysaccharides can bind tightly to the SARS-CoV-2 viral protease, which indicates that P. oleracea is a potential inhibitor for COVID-19.
Adult-onset Neurological Langerhans Cell histiocytosis and Response to Treatment
Authors:   Department of Neurology, Henry Ford Hospital, USA, R Al-Hader , A Suneja ,   Department of Neurology, Henry Ford Hospital, USA, AB Memon ,   Department of Neurology, Henry Ford Hospital, USA, A Mukherje ,   Department of Pathology, Henry Ford Hospital, USA
Published: May 2021

Introduction: Langerhans Cell Histiocytosis (LCH) is a rare form of cancer that mostly affects children and rarely adults. LCH involves an abnormal clonal proliferation of Langerhans cells in the bone marrow. These cells are capable of migrating from the skin to lymph nodes. Therefore, it is characterized as a multisystem disease. Neurological manifestations are not common, and often patients’ present with endocrine dysfunction with neuroimaging findings of hypothalamic and pituitary masses can mimic pituitary adenoma. Here, we discuss two instances of unusual adult-onset, primary neurological LCH in patients with a positive response to therapy-these two patients presented with mass lesion and neurodegenerative form of LCH, respectively. LCH can manifest features of mass lesions or neurodegeneration on brain Magnetic Resonance Imaging (MRI). Since it is rare in adults, it is crucial to identify this condition as timely treatment can have a better prognosis.
Molecular Analysis of Hepatitis B Virus in Mothers-Children Pairs
Authors:   Department of Paediatrics, Medical School, University of Crete, Heraklion, Greece, V Chatzidaki , C Perdikogianni ,   Department of Paediatrics, Medical School, University of Crete, Heraklion, Greece, E Galanakis ,   Department of Paediatrics, Medical School, University of Crete, Heraklion, Greece, D Paraskevis ,   Department of Hygiene and Epidemiology, National and Kapodistrian University of Athens, Greece, I Iliopoulos ,   Laboratory of Bioinformatics, Department of Basic Sciences, Medical School University of Crete, Heraklion, Greece, G Sourvinos ,   Laboratory of Clinical Virology, Medical School, University of Crete, Heraklion, Greece, E Kouroumalis ,   Department of Gastroenterology, Medical School, University of Crete, Heraklion, Greece
Published: May 2021

ackground: Vertical transmission of Hepatitis B Virus (HBV) is the primary infection source for infants, but little is known on the proportion of children that have acquired HBV from their mothers. Objective: We investigated the relationship of HBV sequencing in HBVpositive children and their mothers and explored the HBV phylogenetic tree. Methods: Serum-extracted HBV-DNA from 38 individuals (13 children paired to nine mothers, 16 unpaired infected children) was amplified by polymerase chain reaction and the target region HBV surface glycoprotein (amino acids 40-171) was directly sequenced. Following editing and alignment of these sequences, phylogenetic tree analysis was performed using the neighbourjoining and maximum-likelihood methods. Results: Analysis was successfully performed in 29 subjects (23 children and six mothers), including six mother-child pairs. All individuals were infected by genotype D. Subgenotype adw3 prevailed (21, 72.4%), followed by ayw2 (4, 13.8%) and ayw3 (4, 13.8%). Among six mother-child pairs, three had identical and three had different subgenotypes. Phylogenetic analysis revealed that HBV sequences from three children did not cluster with their siblings suggesting a different source of infection. Conclusion: Our findings suggest that HBV subgenotypes in infected children may not be identical to their mothers’ and point to non-vertical HBV transmission in childhood.
A Seroprevalence Study for HBV in Pregnant Women in Greece: High Risk Migrant Groups and Opportunities for Intervention
Authors:   Department of Neonatology and NICU, University Hospital of Heraklion, University of Crete, Greece, N Anagnostatou , E Hatzidaki ,   Department of Neonatology and NICU, University Hospital of Heraklion, University of Crete, Greece, E Galanakis ,   Department of Pediatrics, University Hospital of Heraklion, University of Crete, Greece
Published: May 2021

Background: Perinatal transmission of HBV leads to chronic infection in up to 90% of neonates. Focused prenatal screening and appropriate treatment of pregnant women and neonates is necessary for the elimination of hepatitis B, as was stated in the 2017 WHO Action Plan for HBV. Information on seroprevalence of HBV in Greece, especially in pregnant women, is scarce and rather outdated. Seroprevalence data specifically for high-risk groups, such as immigrants, is necessary for proper public health planning and elimination of vertical transmission and this study will struggle to fill the gap that exists in Greece. Methods: HBsAg status of pregnant women delivering during 2017 in Crete was studied. Seroprevalence was estimated for the whole population and each ethnic group separately. Results: The mean age of the participants was 30.38 (±6) years. Their origin was Greek (76.76 %), Albanian (10.18%), Bulgarian (3.79%), Roma population (2.44%), Russia and Former Republics of Russia (2.06%), Romanian (1.95%), Central Europe (0.70%) refugees from Syria, Morocco, Egypt (0.55%), and East Asian (0.43%). The HBsAg (+) seroprevalence was 1.5%. The seroprevalence of Greeks was 0.5%, while Albanians, Bulgarians, Romanians and Roma had 4.3%, 5.7%, 2.8%, and 11.1% respectively (p<0.001). Conclusions: Defining specific at-risk groups in each country is fundamental, since MTCT is the principal mode of transmission in high prevalence settings. Our study revealed high seroprevalence in certain migrant groups and Roma women. This information is essential for proper planning of perinatal care in Greece, especially taking into account that these underprivileged groups often lack quality health care.
Vital rates of two small populations of brown bears in Canada and range-wide relationship between population size and trend
Authors: McLellan ML , McLellan BN , Sollmann R , Wittmer Heiko
Published: May 2021

Identifying mechanisms of population change is fundamental for conserving small and declining populations and determining effective management strategies. Few studies, however, have measured the demographic components of population change for small populations of mammals (<50 individuals). We estimated vital rates and trends in two adjacent but genetically distinct, threatened brown bear (Ursus arctos) populations in British Columbia, Canada, following the cessation of hunting. One population had approximately 45 resident bears but had some genetic and geographic connectivity to neighboring populations, while the other population had <25 individuals and was isolated. We estimated population-specific vital rates by monitoring survival and reproduction of telemetered female bears and their dependent offspring from 2005 to 2018. In the larger, connected population, independent female survival was 1.00 (95% CI: 0.96–1.00) and the survival of cubs in their first year was 0.85 (95% CI: 0.62–0.95). In the smaller, isolated population, independent female survival was 0.81 (95% CI: 0.64–0.93) and first-year cub survival was 0.33 (95% CI: 0.11–0.67). Reproductive rates did not differ between populations. The large differences in age-specific survival estimates resulted in a projected population increase in the larger population (λ = 1.09; 95% CI: 1.04–1.13) and population decrease in the smaller population (λ = 0.84; 95% CI: 0.72–0.95). Low female survival in the smaller population was the result of both continued human-caused mortality and an unusually high rate of natural mortality. Low cub survival may have been due to inbreeding and the loss of genetic diversity common in small populations, or to limited resources. In a systematic literature review, we compared our population trend estimates with those reported for other small populations (<300 individuals) of brown bears. Results suggest that once brown bear populations become small and isolated, populations rarely increase and, even with intensive management, recovery remains challenging.
The First Three Years of Presidential System of Government in the Light of Basic Principles, Practices and Revision Requests
Authors: KIZILKAYA Ahmet
Published: May 2021

Turkey adopted a new management model which is also called the Presidential System of Government by referendum held on April 16, 2017. This model has come into force after the elections held on June 24, 2018, and Recep Tayyip Erdoğan became the first president of the Presidential Government System. Eventually, Turkey has moved away from the parliamentary system which is shaped in the developmental stages of Turkish-Ottoman modernization and has approximately 150-years history and adopted a new management model of presidential system which can be considered as a Turkey-specific version. In the scope of this study, the basic principles and implementation practices of the Presidential System of Government, which is about to complete its third year, and the revision requests emerged in the process are discussed. The aim of this study is to reveal the uniqueness of Turkey's new management model, and to show what the equivalence of the system corresponds to in the constitutional law literature context.
Genç İşsizlik, İhracat ve Büyüme Arasındaki İlişki: Türkiye İçin Ampirik Bir Analiz
Authors: KARAKUŞ Mustafa , ÖZEN ATABEY Aslı
Published: May 2021

Ekonomik büyüme ve diğer makroekonomik değişkenler arasındaki ilişki uygulamalı literatürde sıkça ele alınan konular arasında yer almaktadır. Bu çalışma Türkiye'deki 1988-2019 donemi boyunca genç işsizlik, ihracat ve ekonomik büyüme ilişkisini inceleyerek literatüre katkı yapmak amacıyla hazırlanmıştır. Çalışmanın ampirik analiz kısmında ilk olarak değişkenlere birim kök testleri uygulanarak durağanlıkları tespit edilmiş ve ardından VAR modeli kurulmuştur. Daha sonra Toda-Yamamoto testi ile değişkenlerin birbirleri arasındaki nedensellik ilişkisi araştırılmıştır. Bulgular, ekonomik büyümenin ihracatı etkilediğini ancak ihracat değişkeninden ekonomik büyümeye doğru nedensellik ilişkisi bulunmadığını göstermektedir. Bu sonuç “Büyüme Çekişli İhracat” teorisini destekler niteliktedir. İhracatın her ne kadar ekonomik büyüme üzerinde etkisi olmadığı sonucuna ulaşılsa da genç işsizliği etkilediği tespit edilmiştir. Ayrıca ampirik analiz neticesinde değişkenler arasında başka herhangi bir nedensellik ilişkisi bulunmadığı sonucuna ulaşılmıştır.
Implementing Community-Engaged Participatory Research Methods in a Study of Cree Women’s Wellness: Describing Recruitment Processes and Outcomes
Authors: Khetarpal Nitya , Listener Luwana , Oster Richard , Ross Sue , Voyageur Cora
Published: May 2021

Background: In 2017, the Sohkitehew Group was funded to undertake research to identify wellness strategies adopted by mature women as they age in the rural Cree community of Maskwacis, Alberta. We describe our recruitment processes and outcomes for events from July 2017 to June 2018, the first phase of this research.
Methodology: Data gathered from minutes of 36 Sohkitehew Working Group and two Elders Advisory Committee meetings were used to identify recruitment strategies, event characteristics and recruitment outcomes for two large community events and three Sharing Circles.
Results:1. Recruitment strategies: Strategies were similar for community events and Sharing Circles: event posters were displayed throughout Maskwacis, and advertisements were broadcast by Hawk Radio and appeared in Band newsletters.2. Event Characteristics: Settings included a large community gymnasium for large events, and smaller community venues in different Bands for Sharing Circles. Traditional/cultural protocols were addressed by smudging meeting spaces, inviting community Elders to attend all events, and saying prayers. Healthy lunches were provided.3. Event attendance: The two larger community events attracted 96, and 37 participants, respectively. Sharing Circle attendance ranged from 8 to 23 participants.
Conclusion: Recruitment strategies succeeded for the Sohkitehew events in Maskwacis. Prior trusting and respectful relationships with the community established over several years provided a firm basis for this research. Successful recruitment efforts required time, planning, flexibility, and careful attention to culture and tradition to meet objectives to attract participants. Similar strategies may be successful in other rural Indigenous communities if tailored for the specific needs and expectations of individual communities.
Inhibition of α-glucosidase Activity Seed Extract from Mahogany (Swietenia macrophylla King.)
Authors: Nurcholis Waras , Muthoharoh Rini , Ratu Antonius Padua
Published: May 2021

Diabetes mellitus is a chronic disorder that affects the metabolism of blood glucose inside the body. One of the alternative treatments is by using traditional medicinal plants, which have hypoglycemia effects. A mahogany seed is one of the traditional medicinal plants that has been proven to treat diabetes and has been used for generations.  In the aqueous extract, ethanol 96 %, ethyl acetate, and hexane from mahogany seeds (Swietenia macrophylla King.) the inhibition of α-glucosidase activity are checked by measuring p-nitrophenol from p-nitrophenyl-α-D-glucopyranose (pNPG) on 400 nm.  The percentage value of the inhibition for α-glucosidase ranged from 6,36-56,77 %, with 96 % ethanol extract that has the highest value and the hexane extract with the lowest value.  Phytochemical screening revealed the presence of alkaloids, flavonoids, saponins, and triterpenoids, which could be responsible for the bioactivities shown by the 96 % ethanol extract and aqueous extract of S. macrophylla. 

Keywords :  α-glucosidase activity, diabetes mellitus, mahogany seeds (Swietenia macrophylla King.), phytochemical screening.
A case report on Meigs’ syndrome and elevated serum CA-125: A rare case report
Authors: Divya Khanduja , NC Kajal
Published: May 2021

Meigs syndrome is an uncommon presentation, where a benign ovarian neoplasia presents along with ascites and pleural effusion. About 1% of ovarian neoplasia can present as Meigs syndrome. Patients with Meigs’ syndrome and elevated serum CA-125 are not frequently reported. We report a case of a 50-year-old women who presented with shortness of breath, cough, weight loss of one and half month duration. Chest radiograph of the patient with clinical examination of patient confirms pleural effusion as cause of progressive shortness of breath. The presence of a pelvic mass and elevated serum CA-125, which raised the possibility of malignancy. After complete resection of tumor, the pathologic reports confirmed a benign ovarian neoplasia. We highlight the importance of suspicion, careful general examination, radiological assessment and histological tests to confirm the diagnosis of Meigs’ syndrome.
Los conflictos étnicos: compañeros incómodos del multiculturalismo
Authors: León Luis Vázquez
Published: May 2021

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Variation of Iodine Mass and Acetylation Time On Cellulose Acetate Synthesis From Rice Straw
Authors: Umaningrum Dewi , Astuti Maria Dewi , Nurmasari Radna , Hasanuddin Hasanuddin , Mulyasuryani Ani , Mardiana Diah
Published: May 2021

Cellulose acetate is a membrane material that can be used in the sensor field. One source of cellulose acetate is from rice straw. This study aimed to study the effect of iodine mass and acetylation time on cellulose acetate synthesis from rice straw. The initial step is to isolate cellulose from rice straw, followed by cellulose acetate synthesis using iodine catalyst by varying the amount of iodine as much as 0.1-0.3 grams and acetylation time for 1 until 5 hours. The cellulose acetate was characterized using an infrared spectrophotometer, and its viscosity was determined. The result shows that the cellulose 33.63%. The maximum time of cellulose acetate acetylation is 2 hours with a mass of iodine 0.2 g. The yield of cellulose acetate was 14.98%, with an acetyl value of 19.11% and a degree of substitution of 0.89. The cellulose acetate produced has a low viscosity. The FTIR characterization of cellulose acetate shows O-H functional groups at 3333 cm-1, C-H functional groups at ​​2897 cm-1, carbonyl functional groups at 1722 cm-1 C-O functional groups at 1029 cm-1 that were identical in cellulose acetate compounds. The amount of iodine and the acetylation time affected the cellulose acetate product.
The Effectiveness of Magnetite Modified Gallic Acid Synthesized by Sonochemical Method As AuCl4- Adsorbent-Reductor
Authors: Rahmayanti Maya , Santosa Sri Juari , Sutarno Sutarno , Paweni Astuti
Published: May 2021

In recent years gallic acid has been developed as an AuCl4- adsorbent-reducing agent. In this research, gallic acid was modified with magnetite by sonochemical method (GA-Fe3O4), and its effectiveness as an AuCl4- adsorbent was studied. GA-Fe3O4 was synthesized through one-stage (GA-Fe3O4-SK1) and two-stage (GA-Fe3O4-SK2) methods. The effectiveness of GA-Fe3O4 was studied through optimization studies on pH, time, kinetics, and isotherm adsorption of AuCl4-. The adsorption method used was the batch method in the pH range 2-7. While the kinetics model used was the Lagergren and Ho kinetics model. The adsorption isotherm model used was the Freundlich and Langmuir isotherm model. The results showed that the optimum pH conditions for adsorption of AuCl4- on GA-Fe3O4 occurred at pH 3. Adsorption of AuCl4- on GA-Fe3O4-SK1 and GA-Fe3O4-SK2 both followed the Ho kinetic model, while the adsorption isotherm followed the Freundlich isotherm model with values KF were 0.041 and 0.034 mol/g respectively.
ANALISIS KOMPARATIF BAHASA BENGKULU, REJANG, DAN ENGGANO
Authors: Afria Rengki , Izar Julisah , Anggraini Ririn Dwi , Fitri Delvi Hestia
Published: May 2021

Penelitian ini bertujuan untuk mendeskripsikan analisis komparatif bahasa Bengkulu, Rejang, dan Enggano. Metode yang digunakan adalah metode kualitatif dan kuantitatif. Metode dan teknik pengumpuan data yang digunakan adalah metode cakap dan rekam. Metode dan teknik analisis data yang digunakan adalah metode perbandingan, leksikostatistik, dan glotokronologi Hasil penelitian didapatkan kekerabatan bahwa bahasa Enggano, Bengkulu dan Rejang hanya terdapat 27 data yang menyatakan bahwa bahasa tersebut berkerabat. Sedangkan 171 data yang menunjukan bahasa Bengkulu dan bahasa Rejang berkerabat, 26 data yang menunjukan bahasa Rejang dan Enggano berkerabat, dan 27 data yang menujukan bahasa Enggano dan Bengkulu berkerabat. Berdasarkan hasil perhitungan antara bahasa Bengkulu dan Rejang dari 200 kosakata, ditemukan 85,5% kata yang berkerabat. Maka dapat ditentukan bahwa kedua bahasa tersebut tergolong dalam kategori rumpun bahasa.Kata kunci: analisis; komparatif; leksikostatistik; glotokronologi
CITRA TOKOH UTAMA PEREMPUAN DAN NILAI PENDIDIKAN KARAKTER DALAM NOVEL CARNATION KARYA SANAZ NADYA
Authors: IRMA CINTYA NURIKA
Published: May 2021

Karya sastra merupakan cerminan dari kehidupan manusia, salah satunya perempuan yang beragam watak sifat di dalam kesusastraan itu sendiri. Dalam sebuah karya sastra juga memiliki nilai pendidikan yang dapat diambil di dalamnya. Dalam penelitian ini  menggunakan tokoh utama dalam novel Carnation,yang memiliki citra perempuan dan nilai karakter pendidikan yang cukup kuat sebagai anak remaja yang menempuh berbagai kondisi perihal kehidupannya. Penelitian ini merupakan penelitian deskriptif kualitatif. Data dalam penelitian ini berupa kutipan dan percakapan yang terdapat dalam novel Carnation karya Sanaz Nadya dan sumber data novel dan buku acuan yang berkenaan dengan penelitian. Teknik pengumpulan data dengan 2 teknik yaitu teknik baca, dan teknik catat. Teknik validitas data dalam penelitian ini dengan trianggulasi data. Tujuan dari penelitian ini adalah menjelaskan tentang citra tokoh utama dan nilai pendidikan karakter dalam novel Carnation karya Sanaz Nadya. Hasil dari penelitian ini adalah tokoh Della memiliki citra diri meliputi aspek fisik: manis, lucu, cantik, salut. Aspek psikis: penyesalan, menangis, pemarah, galak, kecemburuan, bahagia, pemalu, bijak, agresif. Ada juga citra sosial, yaitu: aspek keluarga. Nilai pendidikan dalam novel Carnation karya Sanaz Nadya meliputi: tanggung jawab, peduli sosial, disiplin, kerja keras, berbakti kepada orang tua, kasih sayang. Kata Kunci : citra perempuan, novel Carnation, nilai pendidikan karakter
Association between the Arylalkylamine N-Acetyltransferase (AANAT) Gene and Seasonality in Patients with Bipolar Disorder
Authors: Yang So Yung , Hong Kyung Sue , Cho Youngah , Cho Eun-Young , Choi Yujin , Kim Yongkang , Park Taesung , Ha Kyooseob , Baek Ji Hyun
Published: May 2021

Objective Bipolar disorder (BD) is complex genetic disorder. Therefore, approaches using clinical phenotypes such as biological rhythm disruption could be an alternative. In this study, we explored the relationship between melatonin pathway genes with circadian and seasonal rhythms of BD.Methods We recruited clinically stable patients with BD (n=324). We measured the seasonal variation of mood and behavior (seasonality), and circadian preference, on a lifetime basis. We analyzed 34 variants in four genes (MTNR1a, MTNR1b, AANAT, ASMT) involved in the melatonin pathway.Results Four variants were nominally associated with seasonality and circadian preference. After multiple test corrections, the rs116879618 in AANAT remained significantly associated with seasonality (corrected p=0.0151). When analyzing additional variants of AANAT through imputation, the rs117849139, rs77121614 and rs28936679 (corrected p=0.0086, 0.0154, and 0.0092) also showed a significant association with seasonality.Conclusion This is the first study reporting the relationship between variants of AANAT and seasonality in patients with BD. Since AANAT controls the level of melatonin production in accordance with light and darkness, this study suggests that melatonin may be involved in the pathogenesis of BD, which frequently shows a seasonality of behaviors and symptom manifestations.
Pengendalian Lampu Berbasis Android
Authors: Ningsih Chelin Srihayati , Juwito Arif Febriansyah
Published: May 2021

Pengendalian Lampu Berbasis Android ini dirancang dengan tujuan untuk membuat simulasi dari rangkaian. Umumnya piranti elektronika pada rumah tangga dikendalikan secara manual, contoh pada lampu. Lampu merupakan sebuah piranti elektronika yang berfungsi untuk penerangan ruangan didalam rumah, sehingga sangat penting untuk kegiatan didalam rumah setiap harinya. Namun saat pengguna memiliki kesibukan, akan terjadi kesulitan untuk menyalakan dan mematikan lampu. Maka diperlukan sebuah sistem pengendalian jarak jauh perangkat atau alat-alat listrik agar lebih mudah dalam penggunanya. Berdasarkan pemikiran tersebut, maka dibuat lah alat yang dapat digunakan untuk mengedalikan lampu rumah dengan jarak menggunakan smartphone android. Sistem yang dibangun memanfaatkan wifi pada android yang dihubungakan dengan module wifi ESP8266 pada Android sebagai perangkat pengontrolan. Hasil dari penelitian alat ini dibuat dari sistem yang dapat berfungsi dengan baik sesuai dengan rencana yang telah dibuat. Pengendalian Lampu Berbasis Android ini dapat dilakukan pengguna melalui Smartphone Android.
Faktor Determinan Struktur Modal Bank yang Terdaftar di Bursa Efek Indonesia Periode 2015-2019
Authors: Mardianto Mardianto , Budiarsyah Gun Gun
Published: May 2021

This research aims to analyze the effect of profitability, asset structure, liquidity, dividend payout ratio (DPR), non debt tax shield (NDTS), growth, company age, and company size on bank leverage. This study relate the empirical findings and try to confirm with pecking order theory or trade-off theory. The research sample is banks in Indonesia which are listed on the Indonesia Stock Exchange for the period 2015-2019 and using multiple linear regression techniques. An appropriate level of profitability, asset structure as collateral with low value, high level of liquidity show conformity to the pecking order, which are negative and significant to bank leverage. DPR as a signal of income prospects and company size shows conformity with trade-off theory, which is positive and significant to bank leverage. Meanwhile, NDTS which shows a decrease in fixed collateral assets, asset growth and bank age do not have any significant effect with bank leverage. If the findings of age and size are compared, it shows that bank leverage does not depend on how long it has been operating, but assets size are more considered. This research fills in the gaps in the research on the determinants of bank leverage, including examining the variables of DPR, NDTS, and bank age which are rarely studied. In the future, the determinant of leverage may consider the agency theory, potential bankruptcy, corporate governance, ownership structure, and macroeconomic conditions.
Analysis of Governance Diversity and Audit Characteristics on Profitability
Authors: Taufiq Muhammad , Fadila Devi
Published: May 2021

This study investigates governance diversity-consisting of female members and national diversity in the board of directors and audit characteristics-consisting of quality and audit tenure on profitability with two proxies, return on assets (ROA) and return on equity (ROE). The investigation uses a stewardship theory to explain the effectiveness of the fiduciary relationship between governance and stakeholders. The regression technique uses panel data with 2.151 data from companies listed on the Indonesia Stock Exchange in 2015-2019. This study demonstrates that audit quality has adverse implications for ROA, while other variables have no effect. It`s findings consistent that female members and audit quality reduce fiduciary relationship-meanwhile national diversity and audit tenure do not have any effect on ROE. This study laid to prove the rating of bad corporate governance and suggests to make disruption in corporate governance characteristics.
DETERMINANTS OF STUDENTS INTEREST IN PURSUING PROFESSIONAL CERTIFICATIONS IN ACCOUNTING
Authors: Rikawati Rikawati , Arumsari Vita
Published: May 2021

This study aims to obtain empirical evidence regarding personality, labor market considerations, professional recognition, financial appreciation and work environment on student interest in taking professional certification in accounting. It uses multiple linear regression analysis with the IBM SPSS (Statistical Package for Social Sciencess) program for Windows version 25. There are 250 respondents in this study from various university in Indonesia. The test results show that personality, job market considerations, professional recognition, financial rewards have an effect on student interest in taking professional certification in accounting, while the work environment does not affect student interest in taking professional certification in accounting.
Video Profil SMK Animasi Bina Nusantara Batam Berbasis Motion Graphic
Authors: Utomo Budi Prio
Published: May 2021

Sekolah Menengah Kejuruan Animasi Bina Nusantara Batam adalah lembaga yang bergerak di bidang pendidikan jenjang sekolah menengah kejuruan yang baru didirikan pada tahun 2018, yang dimana membutuhkan pemanfaatan terhadap perkembangan teknologi pada media promosi baik itu pada media cetak maupun media online. Akan tetapi pada tahun sebelumnya hanya didapatkan media cetak saja seperti baliho, spanduk, brosur dan lainya sehingga banyak masyarakat kurang mengetahui mengenai profil sekolah secara detail, oleh karena itu masyarakat harus langsung mendatangi sekolah seperti pada tahun-tahun sebelumnya. Pembuatan Motion graphic pada video profil SMK Animasi Bina Nusantara Batam menggunakan metode perancangan multimedia versi Villamil-Molina yang terdiri dari tahapan development, preproduction, production, postproduction, dan delivery, yang kemudian video profil ini dilakukan pengujian alfa dan beta serta dilakukan analisis berdasarkan analisis kelayakan produk untuk menentukan bahwa video profil ini sudah layak untuk di publikasikan kepada masyarakat banyak melalui berbagai media. Hasil pengujian produk menunjukan bahwa video profil ini telah memenuhi indikator kelayakan yaitu dari aspek unsur tampilan sebanyak 100%, pengetahuan sebanyak 99% dan pemahaman 100% responden menyetujui bahwa produk telah layak untuk dipublikasikan.
Penyerapan Informasi Masyarakat Terhadap Media Informasi Dinas Kominfo Kota Batam Studi Kasus Pembuatan Kartu Pencari Kerja Online
Authors: Setianingsih Suci Tria , Nelmiawati Nelmiawati
Published: May 2021

Penelitian ini dilaksanakan untuk mengetahui sejauh mana penyerapan informasi oleh masyarakat dan menguji pemahaman masyarakat terhadap media pembuatan kartu pencari kerja online Dinas Kominfo Kota Batam. Dengan menggunakan desain penelitian kuantitatif dan survei, penelitian ini dilakukan terhadap 60 responden (30 responden pengujian video dan 30 responden pengujian website) pada usia produktif dalam bekerja. Pengumpulan data menggunakan pengujian tes yang dilakukan kepada responden berupa pemberian 10 pertanyaan sebelum dan setelah diperlihatkan media. Pengolahan data menggunakan aplikasi IBM SPSS Statistics Subscription Preview untuk Uji Shapiro-Wilk, Paired Sample T Test dan Wilcoxon Signed Rank Test dari data yang telah didapat dari pengujian tes. Didapat hasil dari pengujian Shapiro-Wilk pada sebelum dan setelah diperlihatkan video “Aplikasi Pelayanan Online Kecamatan (APOK) bagian Kartu Pencari Kerja” yaitu sebaran data pengujian tersebut berdistribusi normal dan mendapat nilai 0,0075 < 0,025 pada pengujian Paired Sample T-Test. Selanjutnya, didapat hasil dari pengujian Shapiro-Wilk pada sebelum dan setelah diperlihatkan website https://apok.batam.go.id/ bagian kartu pencari kerja yaitu sebaran data pengujian tersebut tidak berdistribusi normal dan mendapat nilai 0,001 < 0,05 pada pengujian Wilcoxon Signed Rank Test.
A Study on the Model of Animation Style Using PCAF
Authors: Riwinoto Riwinoto
Published: May 2021

Stylized, snappy, and limited animations are three popular movements of animation nowadays. The objective parameters of this style never conducted previously. The researcher proposed a technique named Principle Contained Animated in Frame (PCAF) to obtain the model of animation style. The technique is basically taking information on how often the motion follows the 12 principles of animation. This study begins sampling for all of animated film styles where each style has three examples of films. After getting a percentage of each PCAF on principles of animation, some steps were conducted to find a model. Important steps are unelimination, ascending elimination and final position adjustment. The results of the study at the latest stage showed that the principles of animation numbers 7,3,2,9,10,12 and 16 are the principles formed the special features which are shown in the pattern of stylized animation style, while numbers 4,10,12,2,9,1,6,7 and 3 formed the special features shown in the pattern of snappy animation syle and on the pattern of limited animation style, the principles of which indicated special features form of this style are 2,3,6,11,9 and 12
Determination of the factors affecting pre-service teachers’ technological self-efficacy beliefs by logistic regression analysis
Authors:   Science Education Department A Block, Faculty of Education, Aksaray University, Aksaray, Turkey, Tekin Nurcan
Published: May 2021

Technology transfer to classes has become very important for teachers, regardless of their field. The purpose of this study is to determine how pre-service teachers with high and low level of technological self-efficacy beliefs are predicted by the independent variables. These variables are attitude towards technology, attitude towards instructional technologies and material design course, having a personal computer. The study sample of this relational study consisted of 193 pre-service teachers. As data collection tools, Technological Self-Efficacy Belief Scale, Attitude towards Technology Scale, Attitude towards Instructional Technologies Scale, and a questionnaire developed by researchers were administered. Logistic regression analysis, which is used when the dependent variable is categorical, was employed in data analysis. According to analysis results, the variables of having a personal computer (Wald = 4.23, df = 1, p < 0.05), attitude towards technology (Wald = 13.66, df = 1, p < 0.01) and attitude towards instructional technologies and material design course (Wald = 6.17, df = 1, p < 0.01) had a significant effect on pre-service teachers’ technological self-efficacy beliefs. Particularly, the variable of having a personal computer significantly increased pre-service teachers’ technological self-efficacy beliefs by 20%. In this context, various recommendations were offered to the researchers, institutions and instructors.
Bigger is always not better, less is more, sometimes: the concept of data minimization in the context of Big Data
Authors: Malek Md. Abdul
Published: May 2021

Over 4.1 billion
internet users of the universe generate about 2.5 quintillion bytes of data
each day; and a digital universe of 44 zettabytes will hit 2021. As the data
landscape expands every second every day, the data value also increases by
leaps and bound. Personal data then get revitalized for the disruptive use of
location tracking, predictive policing, fraud detection, healthcare,
advertising media, and entertainment. Likewise, massive amassing of data also at
the same pace gives rise to some new issues regarding the Big Data effects,
including privacy invasion, data breaches, and cyber threats, etc. Taking
efforts for mitigating the risks of data explosion thus becomes imperative for
the society we live in. Accordingly, this paper attempts to focus on the ways
how the data minimization approach mitigates such risks, and how this approach
as a concept is being incorporated in the legal instruments. After suggesting
practical methods on how to reap benefits from the principle, the paper concludes
by exploring the way out of the existing dilemmas so created in the digital
transformation.
Supplemental materials for preprint: KONTROL PERILAKU AGEN MENGGUNAKAN FUZZY LOGIC BERBASIS SEMANTIK
Authors: saleh akuwan
Published: May 2021

?atural language merupakan proses pembuatan model komputasi dari bahasa, sehingga dapat terjadi interaksi antara manusia dengan komputer dengan perantaraan bahasa alami. Model komputasi ini dapat berguna untuk keperluan ilmiah seperti meneliti sifat-sifat dari suatu bentuk bahasa alami maupun untuk keperluan sehari-hari. Bidang-bidang pengetahuan yang berhubungan dengan natural language processing meliputi : Fonetik dan fonologi, morfologi, sintaksis, semantik, pragmatik, discourse knowledge, dan world knowledge. Definisi dari semantik yaitu pemetaan bentuk struktur sintaksis dengan memanfaatkan tiap kata ke dalam bentuk yang lebih mendasar dan tidak tergantung struktur kalimat. Semantik mempelajari arti suatu kata dan bagaimana dari arti kata-arti kata tersebut membentuk suatu arti dari kalimat yang utuh. Proses analisa semantik digunakan untuk mengenali kata-kata yang mendahului dan berhubungan dengan kata yang ada dalam domain. Proses ini dilakukan dengan menghubungkan struktur sintak mulai dari kata, frasa, kalimat, hingga paragraf. Dalam penelitian sebelumnya berkaitan dengan semantic mapping, pemetaan semantik dilakukan berdasarkan pada tampilan fisik dan selanjutnya peran dari suatu model/karakter dalam suatu cerita. Inti dari obyek permainan tidak harus dimunculkan dari tampilan fisik dari suatu karakter saja, tetapi juga dapat dihubungkan dengan parameter penting lain seperti pakaian, alat, benda, senjata yang dibawa oleh masing-masing karakternya.
Differential expression of ankyrin repeat domain 29 in cancers of the breast.
Authors: Mamoor Shahan
Published: May 2021

Breast cancer affects women at relatively high frequency (1). We mined published microarray datasets (2, 3) to determine in an unbiased fashion and at the systems level genes most differentially expressed in the primary tumors of patients with breast cancer. We report here significant differential expression of the gene encoding ankyrin repeat domain 29, ANKRD29, when comparing primary tumors of the breast to the tissue of origin, the normal breast. ANKRD29 mRNA was present at significantly lower quantities in tumors of the breast as compared to normal breast tissue. Analysis of human survival data revealed that expression of ANKRD29 in primary tumors of the breast was correlated with overall survival in patients with luminal A and luminal B subtype cancer, demonstrating a relationship between primary tumor expression of a differentially expressed gene and patient survival outcomes influenced by molecular subtype. ANKRD29 may be of relevance to initiation, maintenance or progression of cancers of the female breast.
“It’s a war! It’s a battle! It’s a fight!”: Do militaristic metaphors increase people's threat perceptions and support for COVID-19 policies?
Authors: Schnepf Julia , Christmann Ursula
Published: May 2021

Governments around the world have made use of militaristic metaphors at the beginning of the COVID-19 pandemic to draw attention to the dangers of the virus. But do militaristic metaphors indeed affect individuals’ threat perceptions and support for restrictive COVID-19 policies? Using a fictitious newspaper design, COVID-19 policies were described with similarly negatively valanced metaphors but different in militaristic connotation (e.g., “war” vs. “struggle”). Overall, data of 3 framing experiments (N = 1,114) in Germany and the United States indicate limited evidence on the effectiveness of the tested militaristic metaphors. In the U.S. context, the non-militaristic concept of struggle was consistently more strongly associated with the desired outcomes than militaristic metaphors. In study 2 and 3, we also tested whether a narrative compared to factual style of reporting additionally influenced the framing effect. A congruency effect of narrative reporting style and the use of warfare metaphors was found in the German but not in the U.S. sample. Results of post-experimental norming studies (N = 437) in both countries revealed that the metaphor of war is associated with higher responsibility ascriptions to the government, whereas the concept of struggle triggers individual responsibility in the pandemic. The results are discussed in light of the usefulness and appropriateness of militaristic metaphors in medical contexts.
Over-estimation of Covid-19 Risks to Healthy and Non-Elderly Predict Support for Continuing Restrictions Past Vaccinations
Authors: Graso Maja
Published: May 2021

I test the possibility that people who provide higher estimates of negative consequences of Covid-19 (e.g., hospitalizations, deaths, and threats to children) will be more likely to support the ‘new normal’; continuation of restrictions for an undefined period of time starting with wide-spread access to vaccines and completed vaccinations of vulnerable people. Results based on N = 1,233 from April, 2021 suggested that people over-estimate Covid-19 risks, and those over-estimates were consistently related to stronger support for continuing restrictions. This relationship emerged in four different samples, using core and supplementary risk estimations, and persisted after controlling for Covid-19 denialism, political ideology, and personal concern of contracting Covid-19. People were also more likely to support continuing restrictions if they believed there is scientific consensus on Covid-19 matters, even on issues where there is none (e.g., wearing masks while driving alone). The study concludes with a discussion of the ethical implications of letting both over- and under-estimation of Covid-19 go uncorrected. Just as it is important to combat misinformation that leads people to disregard health mandates, it is crucial to examine the real possibility that people’s support for continuing risk mitigation practices may also not be based on accurate information.
Filling the gaps: Cognitive control as a critical lens for understanding mechanisms of value-based decision-making
Authors: Frömer Romy , Shenhav Amitai
Published: May 2021

While often seeming to investigate rather different problems, research into value-based decision making and cognitive control have historically offered parallel insights into how people select thoughts and actions. While the former studies how people weigh costs and benefits to make a decision, the latter studies how they adjust information processing to achieve their goals. Recent work has highlighted ways in which decision-making research can inform our understanding of cognitive control. Here, we provide the complementary perspective: how cognitive control research has informed understanding of decision-making. We highlight three particular areas of research where this critical interchange has occurred: (1) how different types of goals shape the evaluation of choice options, (2) how people use control to adjust how they make their decisions, and (3) how people monitor decisions to inform adjustments to control at multiple levels and timescales. We show how adopting this alternate viewpoint offers new insight into the determinants of both decisions and control; provides alternative interpretations for common neuroeconomic findings; and generates fruitful directions for future research.
Examining the structural validity of stereotype content scales – A preregistered re-analysis of published data and discussion of possible future directions
Authors: Friehs Maria-Therese , Kotzur Patrick Ferdinand , Boettcher Johanna , Zöller Ann-Kristin , Lüttmer Tabea , Wagner Ulrich , Asbrock Frank , van Zalk Maarten
Published: May 2021

The Stereotype Content Model (SCM) plays a prominent role in social perception research when comparing the evaluation of different targets on warmth and competence dimensions. However, there is scarce information on the SCM’s measurement properties. Thus, in this article, we provide a comprehensive test of the SCM’S structural validity (i.e., reliability, dimensionality, cross-group comparability of measurement properties). We re-analysed published SCM data from English speaking participants (study 1: 78 datasets from 43 original publications, N = 20,819) and German participants (study 2: 29 datasets from 23 original publications, N = 10,854). We used confirmatory factor analyses to assess the scales’ reliability and dimensionality as well as measurement invariance assessment to examine cross-group comparability as a precondition for meaningful and valid mean-value comparison. We found on average good reliabilities of the SCM scales. In contrast, about 35% of all 1093 examined SCM measurement models presented adequate scale dimensionality, and regarding the scales’ cross-group comparability, we found (partial) scalar measurement invariance in about 11% of all cases. These findings indicate considerable validity concerns in published SCM research, as a meaningful and valid measurement of warmth and competence was not given in approximately two thirds of all cases, and mean-value comparisons were potentially biased due to lacking cross-group comparability for about eight out of nine cases. We propose future directions to improve the measurement quality and validity in SCM research and invite fellow researchers to constructively discuss these ideas.
The Hitchhiker's Guide to Computational Linguistics in Suicide Prevention
Authors: Ophir Yaakov , Tikochinski Refael , Brunstein-Klomek Anat , Reichart Roi
Published: May 2021

Suicide, a leading cause of death, is a complex and a hard-to-predict human tragedy. This article introduces a comprehensive outlook on the emerging movement to integrate Computational Linguistics (CL) in suicide prevention research and practice. Focusing mainly on the state-of-the-art Deep Neural Network models, this "travel guide" article describes, in a relatively plain language, how CL methodologies could facilitate early detection of suicide risk (section 1). Major potential contributions of CL methodologies (e.g., word embeddings, interpretational frameworks) for deepening our theoretical understanding of suicide behaviors (section 2) and promoting the personalized approach in psychological assessment (section 3), are presented as well. Importantly, the article also discusses principal ethical (section 4) and methodological (section 5) obstacles in CL-suicide prevention, such as the difficulty to maintain peoples' privacy/safety or interpret the "black box" of prediction algorithms. Ethical guidelines and practical methodological recommendations addressing these obstacles, are provided for future researchers and clinicians.