bluuebunny/crossref_metadata_2025 huggingface dataset:
Solid-state Fermentation of Cottonseed Meal with Saccharomyces cerevisiae for Gossypol Reduction and Nutrient Enrichment
Authors: Dharmakar Padala , Aanand S. , Kumar Stephen Sampath , Ande Muralidhar P. , Padmavathy P. , Periera Jaculine , Balakrishna Ch.
Published: May 2023

Background: An experiment was conducted to study the effect of solid-state fermentation (SSF) of cottonseed meal (CSM) with Saccharomyces cerevisiae on anti-nutritional factors and amino acid profile. Methods: A finely ground CSM was fermented with baker’s yeast for 48 h at room temperature with periodic observations of pH, temperature and moisture. The fermented substrate was partially sun-dried and nutritional values were observed. Result: After the SSF process on dry basses, the protein content of CSM increased from 8.74% to 12.67%. Besides increasing the nutritional value, the SSF showed a clear significant effect in reducing the anti-nutritional factors content of raw CSM like total gossypol from 0.28% to 0.21%, phytic acid from 3.3% to 0.3% and total tannin from 1.42% to 0.68%. CSM fermented with S. cerevisiae improved concertations of essential amino acids viz., histidine, isoleucine, valine, methionine and phenylalanine. The protein quality evaluation showed a significant increase in its nutritional value. Based on the present result, it can be concluded that the fermentation of CSM with S. cerevisiae decreases the anti-nutritional factors and improves essential nutrients.
Manifestations of students' "clip thinking" in working with a scientific text
Authors: Belousova Alla
Published: May 2023

The purpose of this article is to research the manifestations of clipped thinking in students when reading scientific texts in the educational process. The study involved 42 students in 2-4 courses studying in the direction of "psychological and pedagogical education" at the Taganrog Institute of A.P. Chekhov. To determine the severity of clipped thinking, we used an experimental survey methodology. Based on the material of students' work with a psychological text, the article examines the peculiarities of students' perception and understanding of certain provisions of the text, depending on the degree of severity of the indicators of clip thinking as a cognitive style, characterized by the efficiency of processing information of a significant volume, areflexia, and insufficient criticality. The study revealed that with insufficient comprehension of the text, some students tend to intuitively use the protective mechanism of avoidance, reducing the assessment of some provisions of the text.
Keywords: clip thinking; cognitive style; non-critical reading; reflexive reading; text comprehension.
Membangun Super Enkripsi untuk Mengamankan Pesan
Authors: Agustina Laura , Sujarwo Imam , Khudzaifah Muhammad
Published: May 2023

The issue of message security or an information is particularly important. A science that studies aboutsecuring the confidentiality of messages using passwords is called cryptography. To enhance security, twoalgorithmsarecombinedtosecuremessages.Superencryptionisaconceptthatusesacombinationoftwoormoresubstitutionandpermutation(transposition)cryptographytechniquestoobtainanalgorithmthatis more difficult to crack. The first thing to do is to encrypt the message using a substitution technique(Cipher Substitution), then re-encrypt it using a permutation technique (Cipher Transposition). In thisstudy, two cryptographic algorithms will be combined to build super encryption using the Vigenere Cipherand Bifid Cipher algorithms to secure messages. The message encryption process is using the VigenereCipher algorithm for the first encryption process, then continued using the Bifid Cipher algorithm for thesecondencryptionprocess.Theencryptionprocessisdonetheotherwayaround,startingfromthebackoftheencryptionprocess.Thecombinationofthesetwoalgorithmsresultsinmoresecuremessagesecurity.
Pengembangan Game Visual Novel Sebagai Media Pembelajaran Bahasa Inggris Menggunakan Metode ADDIE
Authors: Galindra Geofany , Adnan Fahrobby , Putra Januar Adi
Published: May 2023

The methods and media that are used in the teaching and learning process are crucial to its success. With the use of suitable learning resources, teachers and students can overcome barriers to learning, enabling students to quickly access and comprehend course material. The survey was conducted in SD Negeri 1 Rogojampi, and the findings revealed that teachers only verbally communicated knowledge to the students while they were learning. With the use of an Android-based Visual Novel Game and the ADDIE method, the researcher hoped to innovate in the development of English learning media. Sixth-grade elementary school students who were randomly selected as respondents during the implementation stage were divided into groups that used learning media and groups that did not. According to the expert validation results, learning media are practicable to use and test on respondents. There were no problems in the learning media during the small group test, allowing it to be continued to the implementation stage or the big group test on research respondents. The respondents are put into two groups for comparison purposes: the group that received learning media and the group that did not. The average comparison value between the groups using learning media and the groups not using learning media differs by 2.9, showing that visual novel learning media is both useful and effective as a learning medium.
Penerapan dan Analisis Network Security Snort Menggunakan Intrusion Detection System pada Serangan UDP Flood
Authors: Ilham Karina Fitriwulandari Ilham , Alwi Erick Irawadi , Fattah Farniwati
Published: May 2023

The web server is one type of server that was most frequently attacked because the web server is the most vital means for storing databases. The most frequently used attack is Denial of Service (DoS). DoS is an attack technique against a system by consuming data resources from a server so that the server cannot be accessed again. Therefore, this study aims to design a network security system by implementing an Intrusion Detection System (IDS) using the Snort application as a detection system in the event of a DoS attack on the web server. by implementing Snort on a web server will help network administrators to ensure that the web server is protected from various threats. The results of this study indicates that the Snort rule that has been created has been successfully detecting attacks that have been tested through the LOIC tools.
DIGESTIVE SYSTEM E-MODULE BASED ON INTEGRATED-STEM IN STUDENT’S SCIENCE LITERACY AND LEARNING OUTCOME
Authors: Vinandari Sanny Murti , Hariyadi Slamet , Nuriman Nuriman
Published: May 2023

This article dicussses how the digestive system e-module based on integrated STEM is used to improve student’sscientific literacy and learning outcome. Scientific literacy is a person's ability to understand science, communicate science, and apply scientific knowledge to solve problems so that they have a high attitude and sensitivity to themselves and their environment in making decisions based on scientific considerations. This research is a development research). The method used is development model suggested by Borg and Gall (1989) in Sugiyono (2015). The research stages are, 1) Potential Problems; 2) Data Collection, 3) Product Design, 4) Product Review; 5) Design Revision; 6) Design Validation; 7) Product trial; 8) Product Revision; 9) Mass Product Manufacturing. The result of pre-research question given to students, it is known that from 37 students 34 of them have low or incomplete scientific literacy scores. So that 91.8% of students have a low level of scientific literacy and 8.1% of students have a good level of scientific literacy. The scientific literacy domain which has the lowest score is science attitude and the final product of the learning using e-module is gerd candy made by students. The developed of e-module is based on a STEM approach consisting of four aspects, namely: (1) Science; (2) Technology; (3) Engineering; and (4) Mathematics. This module is developed to increase students’ scientific literacy for four domains, namely: (1) the context of science; (2) Science knowledge; (3) Science competence; and (4) scientific attitude.
EMOTIONAL INTELLIGENCE RELATIONSHIP WITH ACHIEVEMENT LEARNING PHYSICS CLASS X STUDENTS PRIVATE VOCATIONAL SCHOOL OF ST. ALOISIUS RUTENG FOR THE 2019/2020 ACADEMIC YEAR
Authors: Neang Elenora Yulita , Liu An Nisaa Al Mu'min , Rahmawati Ana Silfiani
Published: May 2023

This study aims for intelligent emotional intelligence with student achievement in learning physics class X SMK Swasta St. Aloisius Ruteng for the 2019/2020 academic year. The type of research used is tracking in a quantitative approach. The population in this study were students of class X Light Vehicle Engineering (TKR) SMK St. Aloisius Ruteng and the sample in this study were class X TKR A assigned to 35 people. With the sampling technique purposive sampling. Retrieval of data, namely questionnaires and documentation. Data analysis used normality test, linearity test and hypothesis test. The result of this study is the absence of emotional intelligence with the learning achievement of students in class X SMK Swasta St. Aloisius Ruteng. This is evidenced by the calculation of the correlation test obtained by 0.010 with a sig α = 0.05, so 0.010 <0.05.
APPLICATION OF PROBLEM-BASED LEARNING (PBL) LEARNING MODEL ON CLASS VIII STUDENT'S CRITICAL THINKING ABILITY STATE JUNIOR HIGH SCHOOL 6 BORONG
Authors: Joni Yohana Melci , Kaleka Melkyanus Bili Umbu , Ika Yasinta Embu
Published: May 2023

This study aims to determine the effect of applying the problem-based learning (PBL) model on the critical thinking skills of eighth-grade students of SMP Negeri 6 Borong. The type of research used is quantitative with a quasi-experimental research design (quasi-experimental) with a Posttest- Only Control Group Design. The population in this study were all students of class VIII SMP Negeri 6 Borong totaling 89 people who were obtained using a random sampling technique. The data collection technique used a test in a description test to measure students' critical thinking skills. Data analysis used normality test, normality test, and hypothesis testing. The results of the study using SPSS 24 obtained the results of the research, namely a significant value for (sig 2- tailed) of 0.000 <0.05, which means that there is an effect of implementing the Problem Based Learning learning model on critical thinking skills so that H0 is rejected and H1 is accepted.
IDENTIFICATION OF CRITICAL THINKING CAPABILITIES OF HIGH SCHOOL STUDENTS USING THE INTEGRATED PHYSICS MODULE OF ENGINEERING DESIGN PROCESS (EDP)
Authors: Yustika Devi , Putra Pramudya Dwi  Aristya , Prastowo Sri Handono Budi
Published: May 2023

The Indonesian curriculum states that science education is one of the efforts to improve the quality of people's lives to be able to have knowledge and skills in solving problems. Problem solving skills require capable critical thinking skills to be able to analyze, assess and reconstruct the knowledge they have to solve problems. In addition, the ability to think critically is an important aspect that must be developed according to the competence of 21st-century skills. This research is a type of qualitative research with a case study approach to identify students' critical thinking skills using the Engineering design process (EDP) integrated physics module which is differentiated by gender. The subjects of this study were six students, each consisting of three male students and three female students in class XI MIPA 2 at MAN 1 Jember. The data was collected in the form of observation data, documentation, and interviews. The data collected will be reduced, analyzed based on indicators of critical thinking skills, and presented to then draw conclusions. All data obtained will be tested for validity using triangulation techniques. The results of the identification of critical thinking skills indicate that there are differences in the characteristics of the problem-solving process between male and female students. Female students are better at interpreting problems accurately and in detail than male students. Meanwhile, male students dominate in giving ideas, and even though some ideas are not quite in accordance with the concepts of physics, and are still in doubt. Overall, there is no significant difference between the critical thinking abilities of male and female students. All students tend to still not fully understand the physics concepts related to solutions so that the statements and opinions given regarding solutions tend to be less clear and less logical.
Generalization of Lohwater-Pommerenke's theorem
Authors: Dovbush Piotr Vasilievich
Published: May 2023

In this paper, as an application of Zalcman's lemma in ℂn, we give a sufficient condition for normality of holomorphic functions of several complex variables, which generalizes previous known one-dimensional criterion of A.J. Lohwater and Ch. Pommerenke.
On the average order of the gcd-sum function over the set of square integers
Authors: Bouderbala Mihoub
Published: May 2023

The gcd-sum function is one of the most important functions that has been studied by many researchers in recent years (Broughan, Bordellès, etc.). The gcd-sum function appears in a specific lattice point problem, where it can be used to estimate the number of integer coordinate points under the square root curve. In this paper, we give an average order of the gcd-sum function over the set of squares.
Toward the construction of relativistic thermo-hydrodynamics of an ideal fluid by the method of extended irreversible thermodynamics
Authors: Kolesnichenko Aleksandr Vladimirovich
Published: May 2023

In this paper we constructed thermo-hydrodynamics for relativistic fluid (taking into account the second order of deviation from equilibrium for dissipative heat and viscosity flows) on the basis of extended irreversible thermodynamics. EIT formalism, providing adequate mod-eling of systems close to the equilibrium state, goes beyond the local equilibrium hypothesis by expanding the number of basic independent variables (including dissipative flows), as well as by modifying such conceptual concepts as entropy, temperature and pressure. The evolutionary laws for the main nonequilibrium field quantities of the relativistic system are postulated: 4-vector particle flux, 4-vector energy-momentum and 4-vector entropy flux. In order to derive the consti-tutive equations, a nonlocal Gibbs covariance relation and a nonlocal form of the second princi-ple of thermodynamics with a source of entropy due to additional variables-dissipative flows-were obtained. The defining equations of the hyperbolic type, forbidding superluminal velocities, modified by relaxation terms, have been obtained. The construction of relativistic thermodynam-ics is carried out using the hydrodynamic 4-speed defined by Eckart. The constructed relativistic hydrodynamics has its applications in such important fields of science as nuclear physics, astro-physics and cosmology.
A relação professor e estudante como fator contribuinte para a motivação da aprendizagem no ensino superior
Authors: Santos Charlene Carneiro Quinto dos , Ribeiro Marinalva Lopes
Published: May 2023

Este artigo discute a importância da relação professor e estudante na motivação para a aprendizagem no ensino superior. Trata-se de uma pesquisa de delineamento qualitativo do tipo revisão de literatura, realizada nas bases de dados da Associação Nacional de Pós-Graduação e Pesquisa em Educação, Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal do Nível Superior, Google Scholar e da Scientific Eletronic Library Online, no período de junho de 2012 a junho de 2022, utilizando os termos de busca: “motivação, aprendizagem, educação superior”; “motivação, aprendizagem, universidade”; “motivação, aprendizagem, relação professor e estudante”, empregando o indicador booleano “AND”. Foram selecionados sete estudos que mais se aproximaram do nosso objeto de estudo, a saber, a importância da relação professor e estudante no ensino superior para a motivação da aprendizagem. Os resultados encontrados nos estudos apontaram que a relação professor e estudante amigável, construída com base no diálogo, na democracia e na afetividade constitui um dos fatores contribuintes para a motivação da aprendizagem no ensino superior. Também foi possível identificar a insuficiência de estudos que investigam a relação professor e estudante e a motivação da aprendizagem no contexto universitário levando em consideração a importância do tema para o ensino superior. Em vista disso, salientamos a necessidade da produção de mais estudos que contemplem esta temática.
Intraspecific Differentiation of Francisella tularensis Strains Using Multilocus Real-Time Polymerase Chain Reaction
Authors: Osina N. A. , Sitmbetov D. A. , Bulgakova E. G. , Chekmareva S. S. , Sazanova E. V. , Senichkina A. M. , Lyashova O. Yu. , Osin A. V. , Shcherbakova S. A.
Published: May 2023

The aim of the study was to develop a method for intraspecific differentiation of the tularemia microbe: subspecies tularensis (subpopulations AI and AII), holarctica (biovars japonica, EryS/R), mediasiatica, and novicida using multilocus real-time PCR. Materials and methods. We used 48 strains of F. tularensis of various subspecies, biovars, and subpopulations. Intraspecific appurtenance of the strains was carried out on the basis of the analysis of the RD-1 region variability applying PCR, the sdhA gene by Sanger fragment sequencing and by the disk diffusion method using disks with erythromycin. The selection of primers and probes was performed using the software available at www.genscript.com and GeneRunner 6.5.52. Sequence homology was assessed using the BLAST algorithm and the GenBank NCBI database. Results and discussion. New data on the structure and occurrence of the differentiation regions RD-8, RD-12, RD-28 of FTT1122c gene and its homologous sequences in strains of tularemia microbe of various subspecies have been obtained. Novel RDhm 346 bp in size, characteristic of strains of the subsp. mediasiatica, holarctica, which is deleted in subsp. tularensis and absent in subsp. novicida has been detected. Based on the detection of the FTT1670, FTT1122с, FTT1067, FTW_2084 loci, a multilocus real-time PCR has been developed – “F. tularensis 4c”, providing for identification of all subspecies of the tularemia microbe, separately for the biovar japonica of the Holarctic subspecies and subpopulations AI, AII of the subspecies tularensis. The PCR specificity was confirmed in the study of strains of tularemia microbe from the fund of the “State Collection of Pathogenic Bacteria” at the premises of the Russian Reserarch Anti-Plague Institute “Microbe”. The results obtained expand the concept of intraspecific genetic heterogeneity of tularemia microbe and possibilities of identifying the causative agent of tularemia using molecular-genetic methods. They are important for understanding the processes of adaptation of the pathogen to circulation in the host organism and environmental objects, the course of evolution and formation of new species of Francisella.
Epidemiological Situation on Tick-Borne Viral Encephalitis in the Russian Federation in 2022 and Forecast of its Development for 2023
Authors: Andaev E. I. , Nikitin A. Ya. , Tolmacheva M. I. , Zarva I. D. , Yatsmenko E. V. , Matveeva V. A. , Sidorova E. A. , Kolesnikova V. Yu. , Balakhonov S. V.
Published: May 2023

The aim of this review is to predict the incidence of tick-borne viral encephalitis (TBVE) in the Russian Federation for 2023 based on analysis of the epidemiological situation on TBVE during 2012–2022. Over the decade, the highest incidence of TBVE was registered in the Siberian, Volga and Ural Federal Districts. In 2022, the Ural Federal District took the second place, the share of the North-Western one decreased by almost two times. Ranking of territories according to the rate of TBVE incidence at the level of constituent entities has made it possible to attribute 16 of them to the group of regions with a high epidemic risk, 14 – to medium epidemic risk, and 18 – to a low epidemic risk. In 2022, the incidence of TBVE in Russia increased by 1.9 times compared to 2021, and amounted to 1.34 0/0000. Despite the increase in the incidence of TBVE in 2022, a significant downward trend has been retained. The rate of infection of ticks removed from humans in 2022 was below the long-term average values. PCR and ELISA were applied for tests. Infection rate of ticks from environmental objects when studied by PCR was higher than the multi-year average values, and lower when studied by ELISA. In 2022, 3.5 million people were immunized against TBVE (vaccinated and revaccinated). Emergency immunoprophylaxis with immunoglobulin covered 24.5 % of the people affected by tick bites (children accounted for 34.3 %). The forecast for TBVE incidence in Russia in 2023 remains favorable. It is expected to be reduced to (0.83±0.298) 0/0000. However, there was not only an increase in the number of TBVE cases, but also the proportion of clinical manifestations of the disease, as well as lethal outcomes among those who suffered from tick bites in 2022. If this pattern holds, the incidence of TBVE in 2023 will be higher than predicted, especially in the constituent entities where the share of individuals with manifest forms among those who suffered from tick bites has increased greatly.
Analysis of the Epidemiological Situation of Hemorrhagic Fever with Renal Syndrome in the Russian Federation in 2022 and Forecast of its Development for 2023
Authors: Savitskaya T. A. , Ivanova A. V. , Isaeva G. Sh. , Reshetnikova I. D. , Trifonov V. A. , Ziatdinov V. B. , Magerramov Sh. V. , Khusainova R. M. , Trankvilevsky D. V.
Published: May 2023

The paper provides the analysis of epidemiological process of hemorrhagic fever with renal syndrome (HFRS) in the Russian Federation in the context of federal districts in 2022 and a forecast of the HFRS incidence for 2023. According to the results of the analysis, there was a three-fold increase in the morbidity rates of HFRS in Russia in 2022 as compared to the indicators of 2021. The evidence of epizootiological survey and laboratory studies in certain federal districts of the Russian Federation indicate the continuing tense epidemiological situation on HFRS. In a number of regions of the country, high risk of infection with HFRS is predicted due to the favorable natural and climatic conditions of the winter period 2022/2023 for reservoir hosts of pathogenic for humans Hantaviruses. The findings of infected rodents attest to a high probability of complication of the epidemiological situation in the territories of increased epidemic hazard as regards HFRS.
Methodological Approaches to Assessing the Economic Damage Associated with the Incidence of Hemorrhagic Fever with Renal Syndrome in the Russian Federation
Authors: Ivanova A. V. , Safronov V. A. , Zubova A. A. , Popov N. V. , Kozhanova O. I. , Matveeva N. I. , Vyatkin I. N. , Shcherbakova S. A. , Kutyrev V. V.
Published: May 2023

The aim of the study was to develop methodological approaches to assessing the economic damage associated with the incidence of hemorrhagic fever with renal syndrome (HFRS) and to calculate the economic damage by the example of an outbreak of HFRS in the Saratov region in 2019. Materials and methods. The paper analyzes the economic indicators of the Federal State Statistics Service; data on the incidence of HFRS in the Russian Federation for the period of 2019–2022. To calculate the cost of outpatient and inpatient medical care, as well as the costs associated with the medical follow-up of convalescents, the indicators of the Program of state guarantees of free provision of medical care to citizens for 2022 and for the scheduled period of 2023 and 2024 were used. The calculation of economic losses associated with the payment of temporary disability benefits was carried out according to the equation provided in the Federal Law No. 255-FZ dated December 29, 2006 (as amended on October 07, 2022). Economic losses associated with premature death at an economically active age were calculated based on the value of unproduced GDP due to lost years of life in the corresponding age group. Results and discussion. The costs of treatment, rehabilitation and payment of temporary disability benefits for 1 case of HFRS at the age of 0 to 56.5 years for the female population and from 0 to 61.5 years for the male population amount to 140 495 rubles; over the age of 56.5 years for the female population and 61.5 years for the male population – 95 412 rubles, respectively. Each fatal case of HFRS aged 0 to 16 years among the male population costs the state 38 976 231 rubles; among the female population – 34 708 331 rubles; in active working age – the value of economic damage varies depending on the age of the person who died of HFRS. The economic damage of the outbreak of HFRS in the Saratov Region (2019), taking into account the direct expenditures of the healthcare system and indirect losses of the country’s economy amounted to 441 453 432 rubles. It is of note that the structure of the main damage is dominated by indirect losses in the economy caused by the premature death of people in economically active age.
Teacher's Speech Acts in Indonesian Language Learning at Islamic Boarding School
Authors: Mudiawati Rinda Cahya , Nisyah Khairun , Mulawarman Widyatmike Gede
Published: May 2023

Pesantren, or Islamic boarding school, is one of the places where speech acts occur between teachers and students. The linguistic phenomena in the Islamic boarding school environment are very diverse. This study aimed to describe teachers' speech acts in learning the Indonesian language in class VIII at Islamic Boarding School Salsabila Samarinda, focusing on exploring locutionary, illocutionary, and perlocutionary acts. This study used a qualitative descriptive research method to describe the phenomenon. The data source was the teacher's speech in Indonesian language learning. The data collection techniques used in this research were observation, recording, and transcription. In this study, the data obtained were the results of recordings that were transcribed to obtain written notes from the subject. The data analysis techniques used were collecting, analyzing, and interpreting data. The results showed that the speech acts found in Indonesian language learning are locutionary acts in the form of news and question, illocutionary acts in the form of directive utterances, and perlocutionary acts of convivial and motivational functions. The locutionary acts spoken by the teacher in the Indonesian language learning process were 52 utterances, illocutionary acts were 30 utterances, perlocutionary acts were 25. The teacher’s speech acts in the boarding school environment have particular characteristics like using Islamic terms, Arabic language, and containing religious motivation in the utterances. The results of this research might have implications to contribute to insights about locutionary, illocutionary, and perlocutionary acts in the boarding school environment.
International Class Program Student Management at PTKIN (A Study at UIN Salatiga and UINSI Samarinda)
Authors: Julaiha Siti , Janah Fathul
Published: May 2023

Higher education institutions are responsible for producing graduates who are competitive at local, national, and international levels. One of the breakthroughs made by higher education institutions is an international class program as a distinction and excellence to answer problems in the era of the Industrial Revolution 4.0. The purpose of this study was to find out the management of international class students at UIN Salatiga and UINSI Samarinda. This type of research is qualitative research using a multi-case approach with data collection techniques in the form of observation, interviews, and documentation. The data analysis technique was interactive data analysis. The findings from this research are that the management of international class students at UIN Salatiga and UINSI Samarinda in terms of recruitment is carried out strictly (Arabic and English tests, TPA, interviews). The difference is that at UIN Salatiga all students from various study programs can take part in the selection or recruitment of international classes, while at UINSI Samarinda the selection for international classes is only for the Islamic Religious Education Study Program (PAI). International class learning at UIN Salatiga and UINSI Samarinda use the (regular) curriculum for each study program and then add additional curricula covering foreign languages ​​both Arabic and English, Qur’an memorization, art, or local wisdom. The findings also show some challenges in the implementation of student management such as in the aspect of the curriculum, lecturer’s ability in foreign language use, and the absence of alumni association. Best practice from the results of this research is expected to be applied and becomes a reference for other higher education institutions to have and run international class programs.
The Effect of Lucky Day! If You Lucky Method on Islamic Religious Education Learning Outcomes
Authors: Sufah Faila
Published: May 2023

This research is motivated by the learning outcomes of Islamic religious education students who are still not optimal and methods that are still conventional. The purpose of this study was to determine the effect of lucky day! if you lucky method on learning outcomes of Islamic religious education in fourth-grade students of State Elementary School 01 Belinyu. The research method used a quantitative approach. The type of research is true experimental with a posttest-only control design. Data collection techniques used objective tests in the form of written tests of multiple choice questions. The study population was all students of Elementary School 01 Belinyu, which amounted to 299 students. The research sample was 52 fourth-grade students of State Elementary School 01 Belinyu who were selected using purposive sampling, namely the deliberate selection of samples consisting of 26 experimental class students and 26 control class students. The research instrument was a test. Data analysis used an independent sample t-test. The results showed that there was an effect of lucky day! if you lucky method on the learning outcomes of Islamic religious education fourth-grade students of State Elementary School 01 Belinyu as evidenced by the hypothesis test p-value of .000 < 0.05. Therefore, it can be concluded that the lucky day! if you lucky method has a significant role in improving the learning outcomes of Islamic religious education.
Chemical properties and antioxidant activity of sweetened red ginger extract fermented with kombucha culture
Authors: Budiari Setyani , Mulyani Hani , Maryati Yati , Filailla Euis , Devi Anastasia Fitria , Melanie Hakiki
Published: May 2023

Kombucha is a renowned fermented drink for its diverse health benefits. This research aims to evaluate sweetened red ginger extract as an alternative substrate in making kombucha by observing the chemical properties (pH, total acid, total sugar, total polyphenol, chemical compound profile using LC-MS/MS) and the antioxidant activity. Three variables were varied, i.e., red ginger concentration (1, 5, and 10%), kombucha culture concentration (10 and 20%), and fermentation time (0, 6, and 12 days). The total sugar and pH declined during fermentation while the titratable acidity, polyphenol, and antioxidant activity increased. The kombucha prepared with 20% culture concentration resulted in a greater reduction of pH and increase of titratable acidity, total polyphenol, and antioxidant activity than the one prepared with 10% culture concentration. The red ginger kombucha prepared with 10% ginger and 20% culture in 12 days displayed the highest antioxidant activity. It revealed ten active compounds under the LC-MS/MS investigation, i.e., 3’,4’,5’,5,7,8-hexame-thoxy flavone, 6-gingerol, evodin, isosakuranetin-7-rutinoside, methyl ophiopogonanone A, narirutin, neohesperidin, ononin, sinensetin, and shogaol. This research shows that red ginger extract fermentation using kombucha culture can be an alternative technology to produce red ginger-based functional drinks with healthy organic acids, healthy polyphenols, and antioxidant activity.
The Influence Of Transformational Leadership And Person-Organizational Fit On Innovative Work Behavior Through Knowledge Sharing Behavior In Formal Education Units
Authors: Wahyuningtias Adisti Hakim , Nugroho Sukmo Hadi
Published: May 2023

This research purposes to explore the influence of transformational leadership and person-organizational fit on innovative work behavior through knowledge sharing behavior. This research is a development of previous research on employees in formal education units. The contribution of this research is expected to able providing new information at the theoretical level of human resource management science and become a reference and have positive managerial implications that can be applied in organizations. Referring to the results of previous research and empirical theory related to the learning process of human resource management, this research was conducted using a survey data collection method by spreading questionnaires online. The population in this study amounted to 28,406 teachers, with respondents selected using the purposive sampling method on teaching staff in the formal education unit at East Jakarta area of 105 teachers as research respondent data. In this study using factor analysis and modeling the Structural Equation Model (SEM) Lisrel. The invention of this study related obtained on transformational leadership do not have a significant positive relationship with innovative work behavior, but transformational leadership can have a positive impact on innovative work behavior through the mediation of knowledge sharing. The managerial implication of this research is that there is a need for leaders to engage with their subordinates in building communication and absorbing any new information as well as creating various kinds of innovations that can be applied and in line with organizational goals.
Systematic Literature Review: The Importance Of Work Motivation To Employee Performance
Authors: Nor Moh Fildan , Eliyana Anis , Sridadi Ahmad Rizki
Published: May 2023

Work motivation is one of the crucial keys to improving employee performance. This study aims to describe the factors that affect work motivation and explain the influence of work motivation on employee performance. Through the systematic literature review approach, this study identified 34 articles with the publication year 2018 – 2022 that discussed work motivation. The results showed that the factors that affect work motivation include leadership, work environment, employee training, task characteristics, rewards for performance, career path, and commitment. Seventeen articles describe a significant influence of motivation on employee performance. In comparison, the other three articles show that there is an insignificant influence between work motivation and employee performance.
Improving Vocabulary Mastery of Junior High School Students by Watching Digital Storytelling
Authors: Anggara Septian Dwi
Published: May 2023

Learning vocabulary becomes one of the challenges in language learning. Choosing the right media will help the student to gain new words. Utilizing stories uploaded into digital applications in learning vocabulary can be helpful. This study aims to seek whether Voicethread as the media delivering story improves vocabulary mastery of junior high school students and to find students’ perception of digital storytelling to improve vocabulary mastery. This research is experimental research using quantitative descriptive methods.  There are pre-test and post-test to seek the increasing number of new vocabulary. Also, there is a questionnaire to find the students’ perception of using Voicethread in vocabulary learning. The result of the study reveals that students’ vocabulary increased. The students give positive responses to the use of digital storytelling and recommend using digital storytelling in vocabulary learning. The result also indicates that digital storytelling influences motivation to study independently.
Uveal metastasis arising from thyroid neoplasms: a systemic review of case reports
Authors: Abdollahi Mirsaeed , Nateghian Hooman , Sobhi Navid , Jafarizadeh Ali
Published: May 2023

Purpose: We systematically reviewed the case report literature to identify cases of uveal metastases (UM) originating from Thyroid Cancers (TCs) and evaluate this condition's demographic, ophthalmologic, and oncologic characteristics.
Methods: Web of Science, Medline, and Scopus databases were searched for case reports or series reporting uveal metastasis originating from a thyroid neoplasm. Articles published in any language from inception through November 2022 were searched and screened independently by two reviewers. The quality of the included studies was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Case Reports.
Results: A total of 1049 records were detected. After removing duplicates and screening articles based on title, abstract, and full text, 46 cases from 43 studies were identified. The mean (SD) age of patients at the time of UM diagnosis was 56.521 (±15.68) years (range, 20–83 years), and 16 cases (34.78%) were reported in the elderly (˃64 years). Male patients consisted 56.52% (n=26) of the cases. Sixteen cases happened in the right eye, 19 in the left eye, and 11 cases in both eyes. In total, 39 cases (84.78%) had choroidal involvement. Papillary carcinoma was the most reported type of thyroid cancer in the patients (16/46), followed by follicular (15/46) and medullary (10/46) carcinomas of the thyroid.
Conclusion: Uveal metastases may appear in metastatic thyroid neoplasms. Therefore, physicians should maintain suspicion when ocular symptoms accompany a neck mass or a history of previous thyroid malignancies.
Fast to slow slip transition in analogue experiments of earthquakes
Authors: Yamaguchi Tetsuo , Himeno Yutaka , Yabe Suguru
Published: May 2023

We conducted laboratory earthquake experiments using soft polymer gels with well-defined bumps on both surfaces. We found two distinct slip modes, controlled by the position randomness of the bumps. When bumps are placed periodically, all contact junctions broke simultaneously. Consequently, fast, regular, and large slip events occurred. In contrast, when bumps are randomly positioned, slow and localized slip events prevailed, accompanied by a small stress drop. We developed a simple theoretical model that describes elastic deformation of the media, slip weakening friction for the bump pairs, and configuration irregularity in the bump position. Using this model, we successfully reproduced the fast to slow slip transition. We believe that our simple approach can contribute to understanding the role of fault heterogeneity in fast and slow earthquakes, and the physics of friction between solids.
A competitive epidemic model of two variants
Authors: Niu Ruiwu , Chan Yin-Chi , Liu Simin , Wong Eric W. M. , Wyk Michael Antonie van
Published: May 2023

The competition between pathogens is an essential issue in epidemiology. As the COVID-19 pandemic persists, new variants mutate resulting in further waves of infections. In this work, we propose a simple two-variant susceptible-infected-removed-susceptible (SIRS) model for studying the competitive epidemic processes. We obtain the global basic reproduction number of our proposed model and show that whether the epidemic persists or diminishes depends on the more contagious of the two variants. Furthermore, by studying the stability of the endemic equilibria, given a specific choice of parameters, we can predict which variant, if any, will eventually dominate the competitive epidemic process.Numerical results show that periodic solutions become viable when the two variants’ cross-infectivities are unequal, i.e., recovery from one variant offers unequal protection against the other. In other words, reducing the infectivity of a variant via non-pharmaceutical interventions may trigger periodic or even chaotic behavior and paradoxically cause healthcare demand to increase. Finally, note that our model is sufficiently general so as to be used for studying competitive behavior in other areas of science.
Assessment of adjacent building vibrations induced by metro with a multigrid fully coupled method
Authors: Wang Qihao , Cai Xiaopei , Zhang Qian , Tang Xueyang , Wang Yuqi
Published: May 2023

The vibrations generated by metro operations can cause structural damage and discomfort to occupants adjacent to the metro lines. In this study, a multigrid fully coupled method of metro vehicle-track-station-soil-building systems is proposed to predict and assess building vibrations before construction. This approach facilitates the efficient calculation of the fully coupled system, while ensuring precise simulations through the utilization of multigrid techniques for wheel-rail contact, track, station, soil, and building components. Using the newly-built opera theatre along Beijing metro line 4 as a case, the study demonstrates that the multigrid fully coupled model can predict the dynamics characteristics of metro-induced vibrations and distribution with high accuracy compared with the field tests. Specifically, it was found that metro operations could result in vibrations exceeding specified limits in the opera theatre, particularly at 10 ~ 40 Hz (the building's natural frequency) and 60 ~ 80 Hz (the main frequency band of vibration caused by the metro). Finally, the mechanism of excessive vibration and the effectiveness of targeted vibration mitigation measures were analyzed with the proposed method. These findings have promising implications for wider applications in environmental assessments and control strategies for new metro lines or vibration-sensitive buildings.
First use of a new frugal CPAP device: the LeVe CPAP System, in adult patients with COVID-19 pneumonitis at Mengo Hospital, Kampala, Uganda
Authors: Littlejohns Anna , Please Helen , Musasizi Racheal , Murdoch Stuart , Nampiina Gorret , Waters Ian , Birch William Davis , De Boer Gregory , Kapur Nikil , Ambrozi Tumwesigye , Carol Ninsiima , Noel Nakigudde , Parmar Jiten , Culmer Peter , Lawton Tom , Namulema Edith
Published: May 2023

Background: Continuous positive airway pressure (CPAP) has been a key treatment modality for COVID-19 worldwide. Globally, the demand for CPAP outstripped the supply during the pandemic. The LeVe CPAP device was developed to provide respiratory support for treatment of COVID-19 and tailored for use in low- and middle-income country (LMIC) settings. It was designed using principles of frugal innovation to be oxygen efficient, compatible with a range of oxygen sources, simple to use and sustainable to maintain. Prior to formal trial approval, received in November 2021, these devices were used in extremisto support critically unwell adult patients requiring non-invasive ventilatory support.
Methods: This is a retrospective review of adult patients with COVID-19 pneumonitis, who were treated with advanced respiratory support (CPAP and/or high-flow nasal oxygen, HFNO) at Mengo Hospital, Kampala, Uganda. Treatment was escalated as per standard local protocols for respiratory failure, and CPAP was the ceiling of care. Data were collected on patient demographics, length of time of treatment, clinical outcome, and any adverse events.
Results: Overall 43 COVID-19 positive patients were included in the study. The majority (83.7%) received CPAP only, 4.7% received HFNO only, and 11.6% received a combination of HFNO/CPAP. In terms of demographics, 58% were female and the median age was 58 years (range 28-91 years). The median duration of advanced respiratory support was 7 days (range 1-18 days). Of all patients escalated to HFNO/CPAP, 65.1% were initially commended on the LeVe device. Overall (all device) mortality was 49% and this was similar between those started on LeVe and non-LeVe devices (50% vs 47%).
Conclusions: The LeVe device was the most used CPAP device during the pandemic, bringing the hospital’s number of available HFNO/CPAP devices from two to 14. They were a critical resource for providing respiratory support to the sickest group of patients when no alternative devices were available. The devices appear to be safe and well tolerated with no serious adverse events recorded. This study is unable to assess the efficacy of the LeVe CPAP device, therefore formal comparative studies are required to inform further use.
Profiling N6-methyladenosine (m6A) methylation-related genes in endometriosis towards a diagnostic model
Authors: lin ying , yuan ming , huang yufei , wang guoyun
Published: May 2023

Endometriosis is an inflammatory disease with non-specific symptoms, including chronic pelvic pain and infertility, which affects thousands of women of reproductive age. Early diagnosis of endometriosis remains challenging. We aimed to build a diagnostic model based on m6A methylation-related genes to provide a new perspective on the clinical diagnosis of endometriosis. Two datasets from previous endometriosis studies were selected. GSE51981 was for training and GSE7305 was for validation. The expression of m6A methylation-related genes between proliferative eutopic endometrium from women with and without endometriosis was compared. Most m6A methylation-related genes were down-regulated in eutopic endometrium from women with endometriosis than those without it. The random forest classifier identified 5 significant differentially expressed genes (YTHDF2, NKAP, FTO, ZCCHC4 and HNRNPC) that might be involved in the development of endometriosis by affecting miRNA maturation or immune cell infiltration. These genes were included in a logistic regression to construct a new diagnostic model for endometriosis with an area under the ROC curve of 0.852. The model was tested on another independent dataset（AUC 0.750）and not only diagnosed endometriosis well but also showed how severe it was. We also found that YTHDF2 was very good at diagnosing endometriosis on its own and was correlated with macrophage and neutrophil infiltration that may be important for endometriosis development. In conclusion, this novel diagnostic model using m6A methylation-related genes may be a new method for early non-invasive diagnosis of endometriosis.