bluuebunny/crossref_metadata_2025 huggingface dataset:
What Are the Trends in PCAOB Inspections and the Reported Audit Deficiencies?
Authors: Prasad Ashna L. , Webster John C.
Published: July 2020

Although the Public Company Accounting Oversight Board (PCAOB) inspections commenced in 2003, few studies have analyzed the recurring nature of audit deficiencies both within and across U.S. and non-U.S. firms. This study investigates longitudinal trends in PCAOB Part I audit deficiencies and compares these deficiencies between initial and subsequent inspections. We classify the audit deficiencies contained in the inspection reports into three categories relating to Generally Accepted Accounting Principles (GAAP), Generally Accepted Auditing Standards (GAAS), and Internal Controls over Financial Reporting (ICFR). Using 1,551 inspections conducted over the period 2003–2017, we find that 67% of Part I audit deficiencies in the related reports pertain to GAAP and that triennially inspected audit firms have the highest occurrence of these deficiencies. On average, 22% of audit deficiencies relate to GAAS, with the highest incidence of these deficiencies attributable to annually inspected audit firms. Although ICFR has the least audit deficiencies (11%), we find a significant increase from 2009. We find no significant differences in the mean number of GAAP, GAAS, and ICFR audit deficiencies between first- and second-round inspections. However, we find a significant increase in the mean number of ICFR audit deficiencies between the third- to fifth-round inspections. The audit areas of “revenue recognition,”“inventory,” and “fair value measurements” (i.e., those requiring significant auditor judgment) are the most frequent audit deficiencies identified by the PCAOB. This study provides insights into the frequency and nature of audit deficiencies to stakeholders such as investors, auditors, audit committees, and users of financial statements.
Twenty-six years of LIS research focus and hot spots, 1990–2016: A co-word analysis
Authors: Mokhtarpour Reza , Khasseh Ali Akbar
Published: July 2020

The purpose of this research is to map and analyse the conceptual and thematic structure of library and information science (LIS) research from the perspective of the co-word analysis. The bibliographical records consist of all the research papers published in the LIS core journals between 1990 and 2016 and indexed in Web of Science. ‘CiteSpace’ was used to visualise the co-word network of LIS studies. The frequency of co-occurrence and centrality scores in the overall structure of the field showed that the word ‘Science’ is the most significant and pivotal keyword among the nodes in the co-word network of LIS literature, and in this respect, the word ‘Library’ is in the second place. However, the results of the social network analysis uncovered that in spite of the high frequency of the word ‘library’, the pivotal role of the term has been exposed to decline over the time. The results of the analysis of co-word clusters showed that ‘information seeking and retrieval’ is the most important research focus in the intellectual structure of LIS literature during 1990–2016. Also, analysis of the hot spots of the LIS research based on Kleinberg algorithm indicated that the words ‘Internet’ and ‘World Wide Web’ have attracted the most attention by LIS scholars during the years under study.
Perceptions of Role Transition into Practice among Advanced Practice Providers and Physicians
Authors: Klein Colleen J. , Pierce Lisa , Cooling Melinda , Che Wen , Lizer Shannon
Published: July 2020

This study sought to examine the experiences of advanced practice providers (APPs) as an approach to inform the development of formalized programs for transition into practice and to compare APP ( N = 122) and physician ( N = 84) perceptions of the novice practitioners’ acclimation into a provider role within the first year of practice. Using a cross-sectional survey design, two separate web-based questionnaires were distributed to APPs and physicians. The APPs’ perspectives echoed findings of earlier studies with regard to perceived confidence, feelings of anxiety/fear, and inadequacy. In 16 of 23 paired items, physicians and APPs had similar perspectives about confidence/competence after orientation. Significant differences in their perceptions included amount of physician support, time management, length of time to become a fully functional APP, and independence. Better understanding of the perceptions of APPs and physicians can augment APP preparation for a shifting workforce composition and team-based, interprofessional practice designed to meet the population’s health care needs.
New Editor’s introduction
Authors: Moeller Roger W.
Published: July 2020

I provide a brief personal introduction including my professional background, interests, and qualifications. I invite authors with a wide diversity of interests to submitted manuscripts to the journal.
The narcissistic experience of friendship: The roles of agentic and communal orientations toward friendship
Authors: Sauls Destaney , Zeigler-Hill Virgil
Published: July 2020

Narcissism is associated with a wide array of interpersonal problems. The present studies examined the connections between narcissistic personality features and the experience of friendship. We were interested in the possibility that narcissistic admiration (an agentic form of narcissism characterized by assertive self-enhancement and self-promotion) and narcissistic rivalry (an antagonistic form of narcissism characterized by self-protection and self-defense) may have divergent associations with various aspects of friendship. Study 1 found that narcissistic admiration and narcissistic rivalry had divergent associations with maximizing selectivity and negative friendship attributions that were mediated by the agentic and communal orientations toward friendship. Study 2 found that narcissistic admiration and narcissistic rivalry had divergent associations with friendship commitment that were again mediated by agentic and communal orientations toward friendship. These results demonstrate the similarities and differences between narcissistic admiration and narcissistic rivalry in the context of friendship as well as the important roles that agentic and communal orientations toward friendship play in the connections that narcissistic personality features have with outcomes concerning friendship.
Modified cardiopulmonary bypass circuit for the use of the AngioVac® system in a case with high paradoxical embolization risk
Authors: Schmiady Martin Oliver , Kucher Nils , Nagaraj Naveen , Schürner Anna Maria , Maisano Francesco , Ouda Ahmed
Published: July 2020

The AngioVac® is a vacuum-assisted percutaneous thrombectomy suction system. In critically ill patients, the sudden volume shift can result in abrupt hemodynamic changes thus leading to a cardiac right-left shunt with a high risk of paradoxical embolization. We describe a modified cardiopulmonary bypass circuit for the use of the AngioVac® system that enables full cardiopulmonary support and reduces paradoxical thromboembolic risk.
An Economic Analysis of Intensive Multidisciplinary Interventions for Treating Medicaid-Insured Children with Pediatric Feeding Disorders
Authors: Serban Nicoleta , Harati Pravara M. , Munoz Elizondo Jose Manuel , Sharp William G.
Published: July 2020

Background. Intensive multidisciplinary intervention (IMI) represents a well-established treatment for pediatric feeding disorders (PFDs), but program availability represents an access care barrier. We develop an economic analysis of IMI for weaning from gastronomy tube (G-tube) treatment for children diagnosed with PFDs from the Medicaid programs’ perspective, where Medicaid programs refer to both fee-for-service and managed care programs. Methods. The 2010–2012 Medicaid Analytic eXtract claims provided health care data for children aged 13 to 72 months. An IMI program provided data on average admission costs. We employed a finite-horizon Markov model to simulate PFD treatment progression assuming 2 treatment arms: G-tube only v. IMI targeting G-tube weaning. We compared the expenditure differential between the 2 arms under varying time horizons and treatment effectiveness. Results. Overall Medicaid expenditure per member per month was $6814, $2846, and $1550 for the study population of children with PFDs and G-tube treatment, the control population with PFDs without G-tube treatment, and the no-PFD control population, respectively. The PFD-diagnosed children with G-tube treatment only had the highest overall expenditures across all health care settings except psychological services. The expenditure at the end of the 8-year time horizon was $405,525 and $208,218 per child for the G-tube treatment only and IMI arms, respectively. Median Medicaid expenditure was between 1.7 and 2.2 times higher for the G-tube treatment arm than for the IMI treatment arm. Limitations. Data quality issues could cause overestimates or underestimates of Medicaid expenditure. Conclusions. This study demonstrated the economic benefits of IMI to treat complex PFDs from the perspective of Medicaid programs, indicating this model of care not only holds benefit in terms of improving overall quality of life but also brings significant expenditure savings in the short and long term.
Polish adaptation of the Geneva Emotional Music Scale: Factor structure and reliability
Authors: Chełkowska-Zacharewicz Maria , Janowski Maciej
Published: July 2020

One of the most popular measurement tools used in music-emotion studies is the Geneva Emotional Music Scale (GEMS). The authors conducted a series of studies on Polish samples to confirm the factor structure and the reliability of the Polish adaptation of the GEMS (GEMS-PL). Study 1 ( n = 262) revealed in the confirmatory factor analysis a good fit for both 9- and 10-factor models, with an indication to a better fit of the 10-factor solution. Additional statistical analyses were performed to explore the differences in the number of factors between the GEMS-PL and the original GEMS. Study 2 ( n = 944) performed in laboratory and Internet settings, confirmed the 10-factor model and revealed that all obtained scales had high reliability. The GEMS-PL scales peacefulness, tenderness, tension, joyful activation, nostalgia, sadness, power, transcendence, and wonder correspond with the original GEMS. The additional scale being moved abstracted from the sadness factor is discussed in the context of possible linguistic differences and growing literature on the state of being moved.
New geographies of commemoration
Authors: Sumartojo Shanti
Published: July 2020

This article identifies new geographies of commemoration. These draw on non-representational perspectives that foreground the experiential aspects of commemorative sites and events, drawing these together with methodologies alive to the subtle but excessive feelings that arise in such settings. It argues that one aim of commemoration – to reinforce the contours of national identity – is disrupted by a focus on the experiential world because of the unpredictable and excessive nature of sensory and affective feelings. New research in geographies of commemoration also draws together different temporalities, holding the potential to unsettle and complicate national narratives.
Territory and territorial stigmatisation: On the production, consequences and contestation of spatial disrepute
Authors: Sisson Alistair
Published: July 2020

Territorial stigmatisation emerged over the past decade as the prevailing concept for understanding the phenomenon of disreputable places and the processes by which they are produced. Following the work of Loïc Wacquant, several studies have articulated its centrality to the neoliberal restructuring of capital and the state. Departing from Wacquant, several have also examined the various forms of resistance to territorial stigmatisation. In reviewing this literature, this paper argues and outlines how territory – paradoxically under-theorised in the literature to date – can clarify the production of territorial stigmatisation, the obfuscations and legitimations it performs, and resistance and contestation.
Bodies and persons: The politics of embodied encounters in asylum seeking
Authors: Häkli Jouni , Kallio Kirsi Pauliina
Published: July 2020

In this paper, we propose that there is a politics of encounters centered on the body at play in seeking asylum and refuge, and that it is critical to study how it unfolds from the point of view of both governing and agency. Building on existing work that looks at the role of embodiment in the political struggles of refugees, and leaning on Helmuth Plessner’s original thinking about social embodiment, we develop a theoretical understanding of this political dynamic, illustrating how it can help us make sense of power relations and forms of governance and (latent) resistance involved in it.
The hidden value of large-rotor, tall-tower wind turbines in the United States
Authors: Wiser Ryan , Millstein Dev , Bolinger Mark , Jeong Seongeun , Mills Andrew
Published: July 2020

The significant upscaling of wind turbine size (nameplate capacity, rotor diameter, and tower height) has, to date, been driven primarily by a goal of minimizing the levelized cost of energy. But with wind’s levelized cost of energy now comparable with that of other generating resources, other design considerations besides cost-minimization have grown in importance—particularly as wind’s increasing market penetration begins to impose challenges on the electric grid. We find that taller towers and larger rotors (relative to nameplate capacity) can enhance the value of wind energy to the electricity system and provide other “hidden” benefits. Specifically, in regions where wind penetration has reached around 20%, we find a boost in wholesale market value of US$2–US$3/MWh. This is augmented by transmission, balancing, and financing benefits that sum to roughly US$2/MWh. The aggregate potential value enhancement of US$4–US$5/MWh is comparable with a 10%–15% reduction in levelized costs.
Localization of TRPA1 channels and characterization of TRPA1 mediated responses in dural and pial arteries in vivo after intracarotid infusion of Na2S
Authors: Hansted Anna Koldbro , Jensen Lars Jørn , Olesen Jes , Jansen-Olesen Inger
Published: July 2020

Background

The Transient Receptor Potential Ankyrin 1 (TRPA1) channel might play a role in migraine. However, different mechanisms for this have been suggested. The purpose of our study was to investigate the localization and significance of TRPA1 channels in rat pial and dural arteries.

Methods

Immunofluorescence microscopy was used to localize TRPA1 channels in dural arteries, pial arteries, dura mater and trigeminal ganglion. The genuine closed cranial window model was used to examine the effect of Na2S, a donor of the TRPA1 channel opener H2S, on the diameter of pial and dural arteries. Further, we performed blocking experiments with TRPA1 antagonist HC-030031, calcitonin gene-related peptide (CGRP) receptor antagonist olcegepant and KCa3.1 channel blocker TRAM-34.

Results

TRPA1 channels were localized to the endothelium of both dural and pial arteries and in nerve fibers in dura mater. Further, we found TRPA1 expression in the membrane of trigeminal ganglia neuronal cells, some of them also staining for CGRP. Na2S caused dilation of both dural and pial arteries. In dural arteries, this was inhibited by HC-030031 and olcegepant. In pial arteries, the dilation was inhibited by TRAM-34, suggesting involvement of the KCa3.1 channel.

Conclusion

Na2S causes a TRPA1- and CGRP-dependent dilation of dural arteries and a KCa3.1 channel-dependent dilation of pial arteries in rats.
Patient-level Characteristics and Inequitable Access to Inpatient Electroconvulsive Therapy for Depression: A Population-based Cross-sectional Study: Caractéristiques au niveau du patient et accès inéquitable à la thérapie électroconvulsive pour patients hospitalisés
Authors: Kaster Tyler S. , Blumberger Daniel M. , Gomes Tara , Sutradhar Rinku , Dasklakis Zafiris J. , Wijeysundera Duminda N. , Vigod Simone N.
Published: July 2020

Objective:

A variety of patient characteristics drive the use of electroconvulsive therapy (ECT) in depression. However, the extent to which each characteristic influences the receipt of ECT, and whether they are appropriate, is unknown. The aim of this study is to identify patient-level characteristics associated with receiving inpatient ECT for depression.

Method:

We identified all psychiatric inpatients with a major depressive episode admitted to hospital ≥3 days in Ontario, Canada (2009 to 2017). The association between patient-level characteristics at admission and receipt of inpatient ECT was determined using logistic regression, where a generalized estimating equations approach accounted for repeat admissions.

Results:

The cohort included 53,174 inpatients experiencing 75,429 admissions, with 6,899 admissions involving ECT (9.2%). Among demographic factors, age was most associated with ECT—younger adults had reduced (OR = 0.30, 95%CI, 0.24 to 0.37; 18 to 25 years) while older adults had increased (OR = 3.08, 95%CI, 2.41 to 3.93; 85+ years) odds compared to middle-aged adults (46 to 55 years). The likelihood of ECT was greater for individuals who were married/partnered, had postsecondary education, and resided in the highest neighborhood income quintile. Among clinical factors, illness polarity was most associated with receiving ECT—bipolar depression had reduced odds of receiving ECT (OR = 0.62, 95%CI, 0.57 to 0.69) The likelihood of receiving ECT was greater in psychotic depression, more depressive symptoms, and incapable to consent to treatment and was reduced with comorbid substance use disorders and several medical comorbidities.

Conclusions:

Nearly 1 in 10 admissions for depression in Ontario, Canada, involve ECT. Many clinical factors associated with receiving inpatient ECT were concordant with clinical guidelines; however, nonclinical factors associated with its use warrant investigation of their impact on equitable access to ECT.
Thermo-catalytic pyrolysis of polystyrene in batch and semi-batch reactors: A comparative study
Authors: Inayat Amer , Klemencova Katerina , Grycova Barbora , Sokolova Barbora , Lestinsky Pavel
Published: July 2020

Thermo-catalytic pyrolysis is considered as a promising process for the chemical recycling of waste polymeric materials aiming at converting them into their original monomers or other valuable chemicals. In this regard, process parameters and reactor type can play important roles for an enhanced recovery of the desired products. Polystyrene (PS) wastes are excellent feedstocks for the chemical recycling owing to the capability of PS to be fully recycled. In this respect, the present work deals with the thermo-catalytic pyrolysis of PS in batch and semi-batch reactor setups. The main goal was to perform a comprehensive study on the depolymerisation of PS, thereby investigating the effect of reactor type, catalyst arrangement, feed to catalyst ratio and residence time on the yields of oil and styrene monomer (SM). A further goal was to identify the optimum operating conditions as well as reactor type for an enhanced recovery of oil and SM. It was demonstrated that the semi-batch reactor outperformed the batch reactor in terms of oil and SM yields in both thermal (non-catalytic) and catalytic tests performed at 400°C. Furthermore, it was shown that the layered arrangement of catalyst (catalyst separated from PS) produced a higher amount of oil with higher selectivity for SM as compared to the mixed arrangement (catalyst mixed with PS). Moreover, the effect of carrier gas flowrate on the product distribution was presented.
Black Femininity and Stand Your Ground: Controlling Images and the Elusive Defense of Self-Defense
Authors: Benz Terressa A.
Published: July 2020

Stand Your Ground (SYG) laws are color-blind and gender neutral in language, providing all citizens the right to use deadly force with no obligation to retreat when they experience a “reasonable” threat. However, SYG protections depend on implicit racial and gender biases. Using the case of Siwatu-Salama Ra, the elusive nature of SYG protections is explored as it relates to dominant stereotypes regarding Black femininity. The argument is made that this othering of Black women as aggressive, fearless, and in need of discipline is a miscarriage of justice and provides the ideological groundwork for the exclusion of Black women from self-defense protections.
Antenatal screening for Down’s syndrome: Revised nuchal translucency upper truncation limit due to improved precision of measurement
Authors: Vale Stephen H , Huttly Wayne J , Wald Nicholas J
Published: July 2020

Objective

To determine whether the improved precision of nuchal translucency (NT) measurement used in antenatal screening for Down’s syndrome observed over time as evidenced by a decrease in the multiple of the median (MoM) standard deviation requires a modification to the NT MoM truncation limits to maintain accurate risk estimation.

Methods

Probability plots were derived from the measurements of NT MoM values used in a 2018 audit of 22,362 unaffected pregnancies. The plots were used to determine whether the NT MoM upper truncation limit should be lowered. Validation plots were used to assess the screening accuracy of Down’s syndrome risk estimates calculated from observed NT MoM values in the 22,362 unaffected pregnancies and 69 Down’s syndrome pregnancies for original and revised NT MoM truncation limits.

Results

Probability plots indicated that with improved precision of NT measurements, there was deviation from a Gaussian distribution at less high MoM values than with less precise measurements. Validation plots showed that using the current NT MoM upper truncation limit of 2.5 MoM with improved precision NT measurements overestimates the Down’s syndrome risk (median risk in highest risk category expressed as an odds was 53.3:1 and observed prevalence was 1:1.1). The large discrepancy was corrected by changing the NT upper truncation limit to 2.0 MoM (median risk in highest risk category expressed as an odds was 1:1.78 and observed prevalence 1:2.7).

Conclusion

The NT MoM upper truncation limit should be reduced from 2.5 to 2.0 MoM.
The meaning of dignity for older adults: A meta-synthesis
Authors: Clancy Anne , Simonsen Nina , Lind Johanne , Liveng Anne , Johannessen Aud
Published: July 2020

Dignified care is a central issue in the nursing care of older adults. Nurses are expected to treat older adults with dignity, and older adults wish to be treated in a dignified manner. Researchers have recommended investigating the concept of dignity based on specific contexts and population groups. This meta-synthesis study aims to explore the understandings of dignity from the perspective of older adults in the Nordic countries. Synthesising findings from qualitative studies on older adults’ experiences of dignity has provided important insight into what can be essential for dignified care in a Nordic context. The importance of visibility and recognition for the experience of dignity is an overarching theme in all the studies. The participants’ descriptions mostly implicated an existence dominated by a lack of recognition. The older adults do not feel valued as people or for their contribution to society and strive to tone down their illnesses in an attempt to become more visible and acknowledged as people. Toning down their illnesses and masking their needs can protect their independence. At the same time, becoming less visible can leave them without a voice. The metaphorical phrase protected and exposed by a cloak of invisibility is used to express the authors’ overall interpretation of the findings. Lack of recognition and being socially invisible is a genuine threat to older adults’ dignity.
A Review of Treatment Decision-Making Models and Factors in Mental Health Practice
Authors: Verbist A. Nathan , Winters Andrew M. , Antle Becky F. , Collins-Camargo Crystal
Published: July 2020

Treatment decision making has been influenced by the evidence-based practice movement, which encourages practitioners to make decisions based upon current research evidence, practice wisdom and ethics, and client values or preferences. This article offers a review of the treatment decision-making literature to identify decision-making drivers based on characteristics of the therapist and client. The narrative review includes surveys, case studies, and naturalistic studies of factors and processes involved in treatment decision making for mental health treatment. Naturalistic studies of decision-making factors reveal client problem formulation and motivation have a significant impact on treatment decision making. Implications for the conceptualization of evidence-based practice in social work and future directions for research in decision making are discussed.
Magnetic Resonance Imaging and Outcomes of Osteochondral Lesions of the Talus Associated With Ankle Fractures
Authors: Özcan Seçkin , Koçkara Nizamettin , Camurcu Yalkın , Yurten Hakan
Published: July 2020

Background:

Osteochondral lesions of the talus (OCLTs) secondary to ankle fractures have previously been reported in the literature. However, no study has evaluated OCLTs using magnetic resonance imaging (MRI) following ankle fracture treatment. The purpose of our study was to investigate accompanying OCLTs in patients with an ankle fracture and evaluate its relationship with the clinical outcomes.

Methods:

Fifty-six patients with ankle fractures who were treated with either a nonoperative or operative method at our center between June 2016 and February 2017 were included in this prospective comparative study (37 men and 19 women; mean age, 44.6 ± 13 years; range, 20-65 years). The mean American Orthopaedic Foot & Ankle Society (AOFAS) scores were used to evaluate the clinical results in all patients in the second month and second year. The second-month ankle MR images were evaluated for OCLTs in all patients. Thirty patients were treated operatively and 26 nonoperatively.

Results:

Accompanying OCLTs were detected in 19 of 56 patients (34%). Our results showed no statistically significant association between OCLT and fracture type, as well as the treatment type. In the second postoperative month, the mean AOFAS scores were 87.2 ± 10.8 and 77.6 ± 12.0 in patients with and without OCLTs, respectively ( P = .005). In the second postoperative year, the mean AOFAS scores were 81.3 ± 6.8 and 86.2 ± 8.4 in patients with and without OCLTs, respectively ( P = .031). The mean AOFAS score significantly decreased in the OCLT group in the second-year control, whereas a significant increase was observed in patients without OCLTs ( P = .026 and P < .001, respectively).

Conclusion:

According to our results, the accompanying OCLTs were found in one-third of patients treated for ankle fractures. We observed a significant correlation between OCLT presence and the AOFAS score. According to the AOFAS score, OCLTs statistically significantly affected clinical results at 2 years.

Level of Evidence:

Level II, prospective comparative study.
Using Item Response Theory to Compare Irritability Measures in Early Adolescent and Childhood Samples
Authors: Dougherty Lea R. , Galano Maria M. , Chad-Friedman Emma , Olino Thomas M. , Bufferd Sara J. , Klein Daniel N.
Published: July 2020

Limited psychometric information is available to guide best practices for measuring youth irritability. This report compares performance of irritability measures using item response theory (IRT). Study 1 used a sample of 482 early adolescents and compared the parent- and youth-report affective reactivity index (ARI) and irritability factors derived from the parent-report Child Behavior Checklist (CBCL) and clinician-administered Kiddie Schedule for Affective Disorders (K-SADS). Study 2 combined data from three childhood samples ( N = 811) and compared performance of the parent-report ARI and CBCL and the clinician-administered Preschool Age Psychiatric Assessment (PAPA). The ARI emerged as the best measure of childhood irritability across the developmental periods, while the CBCL and K-SADS provided an adequate amount of information in early adolescents. No measure reliably assessed irritability at modest severity levels. Using IRT across large pools of developmental samples and measures is needed to guide the field in the measurement of youth irritability.
High Biologically Effective Dose Radiotherapy for Brain Metastases May Improve Survival and Decrease Risk for Local Relapse Among Patients With Small-Cell Lung Cancer: A Propensity-Matching Analysis
Authors: Zhuang Qing-yang , Li Jin-luan , Lin Fei-fei , Lin Xi-jin , -lin Huaqin , -Wang Youjia , -Lin Yaobin , Huang Yun-xia , Zhang Xue-qing , Tang Li-rui , Wu Jun-xin
Published: July 2020

To evaluate whether high biologically effective dose (BED) radiotherapy improves local control and survival outcomes for patients with brain metastases (BMs) from small-cell lung cancer (SCLC) and to determine possible prognostic factors. From January 1998 to June 2018, 250 patients with BM from SCLC were retrospectively analyzed. The Cutoff Finder program was used to classify patients by BED. Overall survival (OS) and BM progression-free survival (BM-PFS) were analyzed using the Kaplan-Meier method and log-rank test. A Cox regression model was used to calculate the hazard ratio and 95% CI for prognostic factors for OS among the study population and propensity score (PS)–matched patients. A BED of 47.4 was taken as the optimal cutoff value. Both OS and BM-PFS were significantly improved in the high-BED (>47.4 Gy) than in the low-BED (≤47.4 Gy) group (median OS: 17.5 months vs 9.5 months, P < .001, median BM-PFS: 14.4 months vs 8.3 months, P < .001). Biologically effective dose ( P < .001), Eastern Cooperative Oncology Group performance status ( P = .047), smoking ( P = .005), and pleural effusion ( P = .004) were independent prognostic factors for OS. Propensity score matching with a ratio of 1:2 resulted in 57 patients in the high-BED group and 106 patients in the low-BED group. In the PS-matched cohort, OS and BM-PFS were significantly prolonged in the high-BED group compared with the low-BED group ( P < .001). Biologically effective dose >47.4 Gy improves survival among patients with BM from SCLC. Eastern Cooperative Oncology Group score, smoking, and pleural effusion independently affect OS of SCLC patients with BM.
Investigating the Effects of Stealthing Justifications on Rape Perceptions
Authors: Nguyen Kimmy Khanh , Weeks Cody , Stenstrom Douglas
Published: July 2020

The current research aimed to investigate justifications behind the perception of stealthing—the act of nonconsensual condom removal in previously consented intercourse. Based upon an article by Brodsky that conducted real-life interviews of stealthing activities, justifications for the act were experimentally manipulated after the participants read a scenario involving a depiction of stealthing. A four (Justification: Control, Instinct, Right, Pleasure) × two (Participant Gender: female, male) multivariate analysis on the assessment of various criminality, morality, harm, blame/responsibility items yielded a significant difference in terms of rape determination, but not other criminality measures. Implications for future research are discussed.
Age demographics of subjects enrolled in interventional phase 3 multiple myeloma clinical trials
Authors: Borad Abhilasha , Saeed Hamnah , Toscani Michael , Barone Joseph , Weber Paul
Published: July 2020

The mean and median ages of diagnosis of multiple myeloma range from 70 to 73 years old, with 63% of patients being over the age of 65. Phase 3 clinical trials are designed to study efficacy in the target disease population and are meant to have the most representative subject pool. The purpose of this review is to identify the age demographic of subjects participating in interventional phase 3 clinical trials that aim to treat multiple myeloma and to determine if they encompass the true age demographic of the disease. To complete this review, a search of phase 3 multiple myeloma research trials with reported results was conducted on clinicaltrials.gov, a national, publicly available resource listing clinical trials. Reported mean or median ages of subjects were identified for each trial, and adjusted averages of these values were calculated. Data from 81 clinical trials were assessed, with 42 trials reporting an average mean age of 65.78 years and 15 trials reporting an average median age of 63.29 years. Based on these results, it was determined that the clinical trials reported in this study enrolled patients that were younger than the true age demographic of the disease. There is an unmet need in research in the older population of patients with multiple myeloma, and this may hinder the generalizability and utility of clinical trial results.
Influence of anise (Pimpinella anisum L.) essential oil on the microbial, chemical, and sensory properties of chicken fillets wrapped with gelatin film
Authors: Fathi-Achachlouei Bahram , Babolanimogadam Nima , Zahedi Younes
Published: July 2020

The present study aimed to develop a novel active edible film based on gelatin incorporated with 0, 0.3, 0.6, and 0.9% w/w anise essential oil as a natural preservative and investigate the shelf life extension potential of chicken fillets during 12 days of refrigerated storage. The chicken fillets were wrapped with the essence-free and anise essential oil-loaded gelatin films, and microbial counts, chemical and sensory tests were surveyed during chilled storage. Results showed that aerobic mesophilic bacteria and Pseudomonas spp counts significantly decreased at all levels of anise essential oil during the first week of storage, while psychrotrophs, yeasts, and molds numbers began to reduce at concentrations of 0.6 and 0.9% from day 6. The using of anise essential oil caused a significant decrease of chemical parameters of chicken fillets, and the values of pH, peroxide, thiobarbituric acid reactive substance, and total volatile basic-nitrogen reached from 7.42, 5.7 meq/kg, 2.21 mg malondialdehyde/kg, and 24.94 mg N/100 g for the essence-free wrapped samples to 4.8, 6.35 meq/kg, 1.73 mg malondialdehyde/kg, and 18.78 mg N/100 g for the ones wrapped with 0.9% anise essential oil-loaded gelatin films at the end of storage day. In conclusion, application of gelatin films loaded with 0.6 and 0.9% anise essential oil can be advised for wrapping chicken fillets to prolong the shelf life for at least one week.
Corporate Carbon and Financial Performance Revisited
Authors: Busch Timo , Bassen Alexander , Lewandowski Stefan , Sump Franziska
Published: July 2020

To assess the robustness and sensitivity of the findings in Delmas, Nairn-Brich, and Lim, we conduct a replication and an extension study. In the replication, we use their research design but analyze another time frame. In our extension, we furthermore expand the geographical scope, and use another carbon performance measure as well as a different set of control variables. We show that the finding that higher carbon emissions are associated with higher short-term financial performance is very robust. By contrast, we also find strong evidence for higher carbon emissions being associated with higher long-term financial performance. This outcome is supported by several supplementary analyses and robustness checks. We derive theoretical implications for the debate on tackling grand challenges. Since there seem to be negative financial performance implications for firms reducing carbon emissions, we highlight a clear need for further policy intervention to pave the way for a low-carbon economy.
The Role of Stakeholder Engagement in Environmental Sustainability: A Moderation Analysis of Chain Affiliation
Authors: Jang Yoon Jung
Published: July 2020

It has been widely recognized that corporate efforts to engage with primary stakeholders is vital when seeking to develop environmentally sustainable businesses. This study proposes a testable model that incorporates causal and outcome variables for stakeholder engagement to investigate the moderating effect of chain affiliation on the relationship between the significant variables; managements’ environmental values and leadership (casual factors), stakeholder engagement, environmental performance, and restaurant performance (outcome factors). A web-based survey was administered to top restaurant managers in the United States, and multigroup structural equation modeling was used to analyze the data. It was found that chain affiliation significantly moderated the relationships between the variables in the proposed model. Specifically, managers’ environmental values were found to be important predictors of stakeholder engagement for chain restaurants compared with independent restaurants, and that managers’ environmental leadership was an essential determinant of stakeholder engagement for independent restaurants rather than for chain restaurants. Even though it was not statistically significant, stakeholder engagement was found to be a more critical factor in promoting a restaurant’s environmental sustainability in chain restaurants than in independent restaurants. The effect of environmental sustainability on the financial and nonfinancial performance was found to be similar for both chain and independent restaurants. Theoretical and managerial implications are also offered.
Standardized scleral buckling approach in the management of noncomplex primary rhegmatogenous retinal detachment
Authors: Radice Paolo , Carini Elisa , Seidenari Patrizio , Govetto Andrea
Published: July 2020

Purpose:

To analyze the anatomical and functional outcomes of a standardized scleral buckling approach in patients with noncomplex primary rhegmatogenous retinal detachment (RRD).

Methods:

Retrospective institutional case series of 135 eyes of 131 patients diagnosed with noncomplex primary RRD. All patients underwent scleral buckling surgery with the placement of an encircling 5 mm oval sponge at 15 ± 2 mm posteriorly from the limbus, cryopexy, subretinal fluid drainage, and air tamponade.

Results:

Final anatomical success at 12 months was achieved in all 135 eyes (100%). Primary anatomical surgical success was obtained in 127 out of 135 eyes (94%), while re-detachment occurred in eight out of 135 cases (6%). Primary anatomical success was significantly lower in pseudophakic eyes ( p < 0.001). At the end of the follow-up period, no vision loss was observed in any patient and both sphere and cylinder refraction shift was mild. There was a low rate of postoperative complications. Nine out of 135 eyes (6.6%) developed full thickness macular hole, whether in 24 out of 135 eyes (17.8%) epiretinal membrane development was noticed.

Conclusion:

A standardized scleral buckling approach for primary noncomplex RRD may be effective. The technique is reproducible, easier, and quicker to perform if compared to classic scleral buckling procedures, suggesting that it may represent a valuable surgical option. Special care is needed in the management of pseudophakic RRD due to higher risk of RRD recurrence.
GAVeCeLT-WoCoVA Consensus on subcutaneously anchored securement devices for the securement of venous catheters: Current evidence and recommendations for future research
Authors: Pinelli Fulvio , Pittiruti Mauro , Van Boxtel Ton , Barone Giovanni , Biffi Roberto , Capozzoli Giuseppe , Crocoli Alessandro , Elli Stefano , Elisei Daniele , Fabiani Adam , Garrino Cristina , Graziano Ugo , Montagnani Luca , Prato Alessio Pini , Scoppettuolo Giancarlo , Zadra Nicola , Zanaboni Clelia , Zerla Pietro , Konstantinou Evangelos , Jones Matt , Rosay Hervé , Simcock Liz , Stas Marguerite , Pepe Gilda
Published: July 2020

Background:

Subcutaneously anchored securement devices (or subcutaneous engineered securement devices) have been introduced recently into the clinical practice, but the number of published studies is still scarce. The Italian Group of Long-Term Central Venous Access Devices (GAVeCeLT)—in collaboration with WoCoVA (World Congress on Vascular Access)—has developed a Consensus about the effectiveness, safety, and cost-effectiveness of such devices.

Methods:

After the definition of a panel of experts, a systematic collection and review of the literature on subcutaneously anchored securement devices was performed. The panel has been divided in two working groups, one focusing on adult patients and the other on children and neonates.

Results:

Although the quality of evidence is generally poor, since it is based mainly on non-controlled prospective studies, the panel has concluded that subcutaneously anchored securement devices are overall effective in reducing the risk of dislodgment and they appear to be safe in all categories of patients, being associated only with rare and negligible local adverse effects; cost-effectiveness is demonstrated—or highly likely—in specific populations of patients with long-term venous access and/or at high risk of dislodgment.

Conclusion:

Subcutaneously anchored securement is a very promising strategy for avoiding dislodgment. Further studies are warranted, in particular for the purpose of defining (a) the best management of the anchoring device so to avoid local problems, (b) the patient populations in which it may be considered highly cost-effective and even mandatory, (c) the possible benefit in terms of reduction of other catheter-related complications such as venous thrombosis and/or infection, and—last but not least—(d) their impact on the workload and stress level of nurses taking care of the devices.
Enhanced vascular assessment by ultrasound using microbubble contrast after percutaneous decannulation of peripheral veno-arterial extracorporeal membrane oxygenation
Authors: Au Shek Yin , Chan Kwong Shun , Fong Ka Man , Yung Sai Kwong , Ng Wing Yiu George , Leung Kit Hung Anne
Published: July 2020

Termination of peripheral veno-arterial extracorporeal membrane oxygenation support by managing the arteriotomy wound using a percutaneous closure device was reported successful and effective. However, careful assessment by clinical examination and also ultrasound Doppler assessment of the lower limb vasculature after closure is of paramount importance. Complications including pseudoaneurysm, arterial stenosis, and acute thrombosis are not uncommon. In this case report, commercial microbubbles were used as ultrasound contrast to enhance the image quality for better vascular ultrasound and Doppler assessment after veno-arterial extracorporeal membrane oxygenation percutaneous decannulation. A peudoaneurysm was revealed after microbubble injection, which would otherwise be missed.
Pre-schoolers Referred to a Child and Adolescent Mental Health Clinic: A Hospital Quality Improvement Report
Authors: Elgen Irene B , Stikholmen Mariell , Gjestad Rolf , Danielsen Inger Lande , Fevang Silje
Published: July 2020

Objective:

Aim of the study was to evaluate the patient pathway from referral to assessment and diagnosis of pre-schoolers referred to a Child and Adolescent Mental Health Clinic (CAMHC) in Norway.

Method:

Following data were collected retrospectively from medical records over a 2-year study period: data from clinical interviews for diagnostic evaluation, observation findings in kindergartens and the CAMHC, and results from medical examinations. The times taken from referral to first contact with the CAMHC, then to the first evaluation, and finally to diagnosis were assessed.

Results:

Of 13 402 pre-schoolers, 88 (0.7%) were referred to the CAMHC, of which 15 refused assessment and 69 completed a diagnostic assessment. Of the assessed children, 15 (21%) did not meet any criteria for an International Classification of Diseases, Tenth revision ( ICD-10) diagnosis, 26 (38%) were diagnosed with developmental disorders, and 10 (14%) were given a non-specific diagnosis. For those children without a specific diagnosis, the mean time taken from referral to CAMHC assessment and diagnosis was longer, although not statistically significant, compared with those with a specific diagnosis ( P = .52). No significant correlation between referral symptoms and final diagnosis was found.

Conclusions:

Pre-schoolers referred to the CAMHC have an increased risk of having developmental disorders. Furthermore, 1 in 5 of the children had comorbidities. We propose more effective health care service by developing an interdisciplinary approach for the management of these children.
Traumatic shoulder fracture-dislocation in a child: An innovative method of closed reduction
Authors: Ikram Mohammad Arshad , Premdas Velummylum Baladas , Alias Mohamad Sallehudin Bin
Published: July 2020

Traumatic shoulder dislocation with proximal humerus fracture is a rare entity among children and treatment is always challenging. We present the case of a child with anterior dislocation of the shoulder associated with complete displaced proximal humerus metaphysis fracture. The fracture was treated by closed reduction using an innovative joystick technique and then fixation by two intramedullary K-wires. The dislocation was easily reduced after the fixation of the fracture. This method of treatment enables us to achieve excellent radiological and clinical results in a short time.
The New Zealand Police Early Intervention System: A review of implementation and impact issues
Authors: Briody Michael , Prenzler Tim
Published: July 2020

This paper examines the implementation process and impacts of an Early Intervention System (EIS) introduced into the New Zealand Police in 2013. The system was associated with large reductions in complaints of 72.5% against target employees ( N = 526), but without this clearly translating into reductions in the overall number of complaints. The New Zealand case also highlighted the issue of the different potential uses of early intervention. Should the priority be officer welfare or the more usual aim of improving officer conduct, police–citizen relations and public confidence in police? The authors argue that the traditional focus on reducing adverse incidents between police and citizens, with public complaints as a major guide and measure, should have at least equal weight in an EIS that is part of a comprehensive state-of-the-art police integrity management system. The paper also highlights the need for detailed publicly accessible data to ensure accountability of investments in integrity strategies.
Discourse markers of Moo in Iraqi colloquial language
Authors: Ahmed Ali Al Fuadi Mohammed
Published: July 2020

This research analyses Moo in the colloquial Iraqi Language discourse marker. Marker co-occurrences are noteworthy features. This focuses on the study of the emotive and textual functions of Moo’s co-occurrences. It has been found that there are seven functions co-occurring with Moo’s that always appear in conjunction with different grammatical structures syntax on the different speech situations. The co-occurrences were used in emotional functions to show denial, causes, inhibition, rebuke, circumstantial, exemplary and questioning. Within one utterance, these markers can occur together, triggering senses that are more complex. Many statements with Moo appear frequently in the form of questions. It seems that the speakers feel more curious about Moo’s questions and ask for more responses. Speakers use coexistence in the context of textual functions to raise the issue, stress, demand answers and negotiate. It was also used when the speakers had just learned to put something to the interlocutors’ attention.