bluuebunny/crossref_metadata_2025 huggingface dataset:
Resistance Patterns in Uropathogens; A Prospective Study of Antibiotic Sensitivity in UTIs and Pyelonephritis
Authors: Rahman Md Siddiqur
Published: January 2025

Background: Urinary tract infections (UTIs) and pyelonephritis are prevalent infections, increasingly complicated by antibiotic-resistant uropathogens, which challenge effective treatment and patient outcomes. Objective: This study aimed to evaluate resistance patterns in uropathogens and assess antibiotic sensitivity in patients with UTIs and pyelonephritis treated at Naogaon Medical College, Bangladesh. Method: This prospective study included 318 patients diagnosed with UTIs and pyelonephritis from January to December 2023 at the Department of Nephrology, Naogaon Medical College, Bangladesh. Urine samples were cultured to isolate uropathogens, and antibiotic susceptibility was tested using the disk diffusion method. Resistance patterns were analyzed for common antibiotics, including trimethoprim-sulfamethoxazole, nitrofurantoin, and ciprofloxacin. Results: Among the 318 patients, Escherichia coli (E. coli) was the most frequently isolated pathogen (64%), followed by Klebsiella pneumoniae (18%) and Proteus mirabilis (10%). Resistance to trimethoprim-sulfamethoxazole was observed in 55% of E. coli isolates, while nitrofurantoin and fosfomycin demonstrated resistance rates of 28% and 12%, respectively. Ciprofloxacin resistance was detected in 43% of isolates. Extended-spectrum beta-lactamase (ESBL) production was detected in 22% of E. coli and 15% of K. pneumoniae isolates. Carbapenem resistance was low (5%), but concerning for future treatment options. Conclusion: The study highlights significant antibiotic resistance in uropathogens, particularly E. coli, complicating the empirical treatment of UTIs and pyelonephritis. Effective local antimicrobial stewardship is crucial to address resistance trends and optimize patient outcomes.
Nutritional Management in Patients with Chronic Kidney Disease: A Focus on Renal Diet
Authors: Hasan Hasibul
Published: January 2025

Chronic Kidney Disease (CKD) is a significant global health issue, contributing to high rates of morbidity and mortality. Nutritional management, particularly through the implementation of a renal diet, is an essential therapeutic strategy in slowing CKD progression and managing associated complications. This case report details the dietary management of Abu Sayed, a 38-year-old male diagnosed with CKD, receiving treatment at Rajshahi Diabetic Association General Hospital. The intervention focused on limiting intake of protein, sodium, potassium, and phosphorus to reduce kidney strain, stabilize electrolyte levels, and manage fluid retention. The report explores the challenges faced the patient in adhering to the renal diet within the context of traditional Bangladeshi cuisine, and highlights the outcomes of the intervention. Over 12 months, dietary modifications led to a stabilization of kidney function, improvement in symptoms, and normalization of electrolyte levels. This case emphasizes the importance of individualized care and patient education in CKD management, particularly in culturally specific settings. Despite some difficulties in dietary compliance, a multidisciplinary approach and continuous follow-up contributed to the successful management of the patient’s condition.
Functional Outcome of Closed Locked Intramedullary Nailing of The Femoral Shaft Fracture
Authors: Ali Dr Md Eunus
Published: January 2025

Background: Femoral shaft fractures are common adult injuries, necessitating effective treatment strategies to optimize patient outcomes. Closed locked intramedullary nailing is widely recommended for femoral shaft fractures due to its high union rates. Objective: This study aims to determine the outcome of managing closed femoral shaft fractures in adult patients using Closed Femur Nailing. Methods: This prospective study was conducted at the Department of Orthopedics, Rangpur Medical College Hospital, and a multicentral private hospital in Rangpur Zone from January 2016 to December 2019. Adult patients aged 16 years and above, presenting with closed femoral shaft fractures within two weeks of injury, were included, while pathological fractures were excluded from the study. Standard techniques were employed for the Closed Femur Nailing procedure, and each patient was followed up for at least 1 year. Results: A total of 112 adult patients were enrolled, with a mean age of 36.9 ± 11.7 years and a male-to-female ratio of 2.9:1. Road traffic crashes were the predominant cause of closed femoral shaft fractures (95.3%), with motorcycle-related incidents being the most prevalent (56.1%). The study demonstrated an impressive union rate of 95.3%, with an average time to radiological union of 14.0 ± 1.2 weeks and a mean time to painless full weight-bearing of 14.2 ± 1.2 weeks. Complications encountered included broken nails (4.7%), infection, loosening of the distal screw, and limb length discrepancy (2.3% each). Thoresen's criteria revealed excellent results in 93% of patients, with poor outcomes in only 4.7%. Conclusion: Closed Femur Nailing emerges as an effective and reliable method for managing closed femoral shaft fractures in adult patients, yielding excellent clinical outcomes with a high union rate and relatively low complication rates.
Enhancing Cervical Cancer Screening VIA vs. Colposcopy; A prospective study
Authors: Khatun Dr Mst Manzuda
Published: January 2025

Background: Cervical cancer is a significant cause of morbidity and mortality globally, particularly in low-resource settings. Visual inspection with acetic acid (VIA) and colposcopy are two widely used methods for cervical cancer screening, but their comparative effectiveness in settings like Bangladesh remains unclear. Objective: This prospective observational study compares the diagnostic accuracy and feasibility of VIA versus colposcopy for cervical cancer screening among women attending the Department of Obs & Gyne at Peerless Diagnostic & Hospital, Naogaon, Bangladesh. Method: A total of 220 women aged 16-55 years, representing various age groups and educational levels, were recruited from January 2021 to December 2023. Participants underwent both VIA and colposcopy examinations, with findings compared against histopathological results from biopsies, when indicated. Sensitivity, specificity, positive predictive value, and negative predictive value of VIA and colposcopy were analyzed. Result: Preliminary results show VIA with a sensitivity of 75% and specificity of 80%, with 40% of participants showing abnormalities, of which 30% were confirmed as true positives. Colposcopy exhibited superior performance, with a sensitivity of 85% and specificity of 90%. Abnormalities were detected in 50% of cases, with 45% confirmed as true positives. Colposcopy resulted in fewer false positives (10%) compared to VIA (20%), indicating its higher diagnostic accuracy. Histopathological confirmation revealed a higher proportion of true positives with colposcopy compared to VIA in women with abnormal findings. Conclusions: Colposcopy exhibits superior sensitivity and specificity compared to VIA in cervical cancer screening among Bangladeshi women.
Assessing the Impact of Laparoscopic Surgery on Metabolic and Reproductive Outcomes in Women with Polycystic Ovary Syndrome
Authors: Borna Nishat Anam
Published: January 2025

Background: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder characterized by reproductive and metabolic dysfunctions. Laparoscopic ovarian drilling (LOD) is a surgical procedure used to restore ovulation in clomiphene-resistant PCOS, but its effects on metabolic outcomes remain controversial. Objective: This study aims to assess the impact of LOD on both metabolic and reproductive outcomes in women with PCOS at Rajshahi Medical College and Hospital. Method: A retrospective cohort study of 244 women with PCOS who underwent LOD between January 2020 and December 2023 was conducted. Patients were evaluated for ovulation rates, pregnancy outcomes, and metabolic parameters, including insulin resistance, body mass index (BMI), and lipid profiles. Statistical analysis was performed using paired t-tests, and p-values less than 0.05 were considered statistically significant. Follow-up assessments were conducted at 3-, 6-, and 12-months post-surgery. Results: The ovulation rate increased significantly, with 68.4% of patients ovulating within six months post-surgery (p < 0.001). The cumulative pregnancy rate reached 55.3% within one year (p < 0.01). Improvements in metabolic outcomes were observed, with 44.7% showing a statistically significant reduction in insulin resistance (p = 0.02) and 36.1% experiencing a significant decrease in BMI (mean BMI reduction of 1.7 kg/m², p = 0.03). However, 19.7% of patients showed no significant changes in metabolic parameters. Postoperative complications, such as adhesion formation, occurred in 4.1% of cases. Conclusions: Laparoscopic ovarian drilling significantly improves reproductive outcomes, with a substantial increase in ovulation and pregnancy rates in women with clomiphene-resistant PCOS.
Feminism and its Aspirational Goal for Gender Equality
Authors:   Polytechnic University of the Philippines-Manila, Ogatis Gerlie
Published: January 2025

Preface
Enforcing the Canon Law:Normative Pluralism and Clerical Abuse in the Catholic Church
Authors:   Polytechnic University of the Philippines-Manila, Ballano Vivencio
Published: January 2025

This article investigates why clerical abuse of Catholic priests persists in the Church using the sociological and
normative pluralist perspectives. It analyzes how the various informal normative standards of the Church—
doctrinal, ethical, or biblical—affect the enforcement of Canon Law on clerical abuse by bishops, particularly on
how they decide on specific cases on the diocesan level. It also investigates how the cultural values and norms
influence the bishop’s decision whether to sanction erring priests or not or to prosecute abuse cases in civil
courts. Unlike the state, the Church has no professional judicial system with a set of legal codes, a hierarchy of ecclesial judges and prosecutors, as well as a comprehensive penal law to assess cases of clerical abuse
objectively following the principle of “rule of law.” Thus, the informal norms of mercy and compassion, eternal
character of the priesthood, camaraderie in the ministry among priests, and other cultural values and norms in the
local culture, tend to dominate over the strict penal provisions of the Canon Law against clerical abuse in the bishops’ investigation and decision. Faced with multiple normative criteria in judging abuse cases and given the
wide ecclesial powers given to them by the Church, local bishops then acquire more discretionary powers to keep
investigations of clerical abuse internally in the spirit of evangelical mercy and compassion in order to preserve
Church’s unity and fellowship of the clergy. This strategy, however, slows down the filing of clerical abuses cases in civil courts and faces the risk of being seen by victims and Church members as a cover-up and grave injustice.
IGOROTISM AND ORIENTALISM:The Photographs of Eduardo Masferré
Authors:   Office for Strategic Communications, De La Salle University, Manila, Philippines, Dela Cruz AARichela
Published: January 2025

This paper seeks to provide a critical reading of the photographs of photographer Eduardo Masferré. The photos reviewed were part of the collection in E. Masferré, People of the Philippine Cordillera Photographs, 1934-1956 published in 1988. The book showcases the body of work of Masferré, a Spanish Filipino who is part of the Kankana-ey tribe through his mother. Considered as the father of Philippine photography, Masferré’s photos mirror his talent as well as reflect images, life, and work of the Igorots in Cordillera. Masferré made it his task to take hundreds of photographs of the Cordillera to document its culture and tradition, display the remarkable knowledge of the Igorots in agriculture, showcase the unique character of the area, and illustrate the humanity of his people. Using the theory of Igorotism and theory of orientalism, Masferre´s photos were analyzed to determine the Igorotist and orientalist elements in Masferre’s photos and how these were formed in his art. This research studied the artist and his works while also seeking to understand the representation of the people of Cordillera in Masferré’s photographs. As Masferré’s body of work was explored, the researcher also looked into the life of Masferré, his influences, and the forces that shaped the Igorotist and orientalist elements in his masterpiece. The findings were interpreted to find out which of these forces prevailed – Masferré’s Igorotism ideology or the invisible orientalist influence.
Perbandingan Metode Klasifikasi Naïve Bayes dan C4.5 untuk Menentukan Potensi Nasabah Pada NSC Finance
Authors: Marhaeni  , Eviana Tjatur Putri  , Gusmana Roman
Published: January 2025

NSC Finance, usaha jasa yang memberikan pinjaman kepada masyarakat untuk memenuhi kebutuhan. Masalah utama dari NSC Finance yaitu belum memanfaatkan data nasabahnya untuk mendapatan informasi yang penting. Tujuan dari penelitian ini melakukan klasifikasi pada data nasabah untuk memperoleh informasi target nasabah mana yang memiliki berpotensi, dipertimbangkan, dan tidak berpotensi untuk penawaran pinjaman kembali. Untuk membantu sistem klasifikasi nasabah lebih akurat, ada beberapa metode yang dapat dibandingkan di antaranya yaitu Naïve Bayes dan C4.5 dengan pengukuran akurasi menggunakan recall precision. Analisa Perbandingan metode ini bertujuan untuk mengetahui metode yang memiliki akurasi tertinggi dalam menentukan klasifikasinya. Dengan adanya perbandingan metode ini perusahaan bisa mengetahui keakuratan tertinggi dalam menentukan hasil klasifikasi diantara 2 metode yang dibandingkan. Hasil penelitian yang ditemukan bahwa proses klasifikasi berdasarkan pola yang terbentuk dari 80 data training dan 20 data testing sehingga memungkinkan masih ada data yang klasifikasinya tidak bernilai sama dengan data aslinya, dan perbandingan metode klasifikasi data mining Naïve Bayes dan C4.5 menunjukkan bahwa Naïve Bayes lebih akurat dari pada C4.5. Hal tersebut dibuktikan dengan nilai akurasi dari Naïve Bayes yaitu 85%, precision 94.44%, dan recall 89.47%.
Implementasi Logika Fuzzy Mamdani dalam Menentukan Jumlah Pemesanan Produk pada PT Forisa Nusapersada Area Tarakan
Authors: Rita Tri Wulandari  , Ummi Syafiqoh  , M. Hafid
Published: January 2025

PT Forisa Nusapersada area Tarakan merupakan sebuah perusahaan industri dalam bidang pendistribusian dan pemasaran produk. Dalam pemesanan produk ke pusat, terkadang perusahaan harus melakukan pemesanan berulang kali dalam sebulan dikarenakan permintaan produk dari customer yang terkadang meningkat dan menurun setiap bulannya sehingga dapat mempengaruhi persediaan produk di gudang.  Penelitian ini dilakukan untuk menentukan jumlah pemesanan berdasarkan data penjualan, stok barang dan barang masuk dari bulan Maret hingga Agustus 2021. Metode yang digunakan dalam penelitian ini yaitu Fuzzy Mamdani. Metode ini memiliki  5 tahapan yang terdiri dari pembentukan himpunan fuzzy, pembentukan rule/aturan, aplikasi fungsi implikasi, komposisi aturan dan penegasan (defuzzifikasi). Variabel input yang digunakan adalah permintaan dan persediaan sedangkan variabel outputnya adalah pemesanan. Hasil penelitian menunjukkan bahwa penentuan nilai domain himpunan fuzzy dapat mempengaruhi hasil akhir yang berbeda untuk setiap varian produk. Dalam penelitian ini, nilai domain himpunan fuzzy yang digunakan berasal dari nilai minimal dan maksimal dari data penjualan, stok barang dan barang masuk.
Implementation of Data Mining Using Hash-Based Algorithm for Drug Expenditure Patterns at Pertamina Tarakan Hospital
Authors: Febriyan Febriyan , Juliansyah Rizky , Sinawati Sinawati , Anto Anto
Published: January 2025

The role of information systems has expanded to other layers of life, especially in the health sector. Improving service and performance productivity in the health sector, including pharmacies. This study identifies drug dispensing patterns at the Pertamina Tarakan Hospital.This research was carried out in several stages. First, create tabular transaction data. Second, determine minimum support. Third, determine the memory address. Fourth, calculate the minimum confidence. Fifth, calculate confidence, and last, make a decision.This study focuses on Rs Pertamina Tarakan to identify common spending patterns. For example, in the previous 12 months, what drug combination was most commonly administered to patients. Knowing dispensing patterns allows Rs Pertamina Tarakan to arrange the layout of medicines, resulting in more optimal and excellent service in the medicine administration department. The results showed that in 2022, three pairs of drug combinations placed close together, namely Ranitidin, Urdahex Cap first pair, Urdahex Cap, Folamil genio kap, Propylathiorasil second pair, and Propylathiorasil, Ranitidin, and Urdahex Cap  third pair.
Promoting pro-environmental behaviours among urban dwellers. A study of the interdisciplinary Greencoin project
Authors: Duda Ewa
Published: January 2025

The presented monograph outlines the course of the Greencoin project activities and their outcomes. Due to the distinct nature of each task and the fact that they were coordinated by the various partners, who bring their own unique perspectives to the table, they are presented in the monograph in a way that reflects this diversity. This approach aims to demonstrate the project’s inherent complexity, which is multi-stage and non-linear, with project tasks occurring concurrently over time. It also considers the diverse theoretical assumptions and perspectives, as well as the project team members’ respective modes of action and tools. Conducting interdisciplinary research in large, often international teams involving people from outside the scientific community is essential if we want to solve environmental problems together, as the climate crisis is not a one-dimensional phenomenon.
Curt Sørensen: Den europæiske deltagelseskrise
Authors: Bryld Claus , Sørensen Curt
Published: January 2025

Debat.
ARBEJDERNES 1.MAJ
Authors: Knudsen Knud
Published: January 2025

I år er det 125 år siden, de første 1. majdemonstrationer blev afholdt – i 1890. Beslutningen om at arrangere internationaledemonstrationer for en 8-timers normalarbejdsdag blev truffet på en international arbejderkongres i Paris i 1889. Det var densamme kongres, der besluttede at oprette en ny socialistisk Internationale – den såkaldte Anden Internationale. De førstemajdemonstrationer i Europa blev afholdt året efter, og de gik ikke stille af. På den baggrund var der god grund til at betegne1. maj som arbejdernes kampdag.
Det kæmpende Danmarks radiostudie og film
Authors: Thing Morten
Published: January 2025

Morten The Fighting Denmark`s Radio and Film Studio, Arbejderhistorie 1/2012, s. 14-30. In connection to the sabotage organization inlate 1944 a little group was built up which called itself the Fighting Denmark`s Radio and Film Studio. The group produced recordings which were etched onto gramophone records. The recordings were about the resistance movement in Denmark and the recordswere transmitted on the BBC`s Danish service. A single direct reportage from a sabotage action was produced by the group, whichwas a great hit with the BBC. In last months of the war the group also produced a film.Rigmor Kaplan was leader while the journalist Kaj Christiansen acted as the voice of the group.
Telefoncentralen som et “Panaudikon”
Authors: Nielsen Jacob Vrist
Published: January 2025

“Tilbage bliver en fornemmelse af, at denne form for kontrol er et hæsligt spioneri, der mest af alt minder om gamle dages slaveopsyn. mærkeligt, at det skulle være nødvendigt endnu på rigstelefonen […] nej, ikke spor mærkeligt. for rigstelefonen er jo overvejende en kvindearbejdsplads.”
Er overenskomster den eneste vej frem for fagbevægelsen?
Authors: Friborg Bjarke
Published: January 2025

Arbejdsstyrken i Danmark er under forandring, men vil nye og voksende faggrupper organisere sig kollektivt? Forskningsprojektet SIV har set på de internationale erfaringer med organiserings- og aftaleformer blandt den globalt voksende gruppe af videnarbejdere. I dette essay undersøges det, om erfaringerne kan inspirere fagbevægelsen i Danmark.
Tony Judt (1948-2010)
Authors: Knudsen Knud
Published: January 2025

Artiklen tegner et portræt af historikeren Tony Judt, der især blev kendt for sit storværk om Europa efter Anden Verdenskrig og for sine kontroversielle historisk funderede vurderinger af vor tids moderne politik. I sine sidste skrifter før sin død i 2010 søgte Judt at formulere programmet for et ”universalistisk Socialdemokrati” i det 21. århundrede.
Fremad og aldrig glemme
Authors: Grelle Henning
Published: January 2025

Socialdemokratiet fejrer i år sit 150-års jubilæum den 15. oktober, stiftelsesdagen for Den Internationale Arbejderforening for Danmark. Ved tidligere jubilæer har andre datoer været i spil, og en forkert blev valgt. Partiets udvikling, sejre og kommende opgaver har siden 25-års jubilæet i 1896 været den skabelon, jubilæer blev fejret med. I partiets vækstår ved 50-års og 75-års jubilæerne varstore demonstrationer og fest på Fælleden med til at vise fremgangen. 150-års jubilæet vil, som traditionen byder, både blive et tilbageblik på de seneste 25 år og forsøg på at udstikke kursen for de næste.
Hundrede procent dansk, hundrede procent amerikaner
Authors: Mogensen Nick Kofod
Published: January 2025

Under Første Verdenskrig blev immigranter i USA set på med mistro. Svækkede det ikke loyaliteten, at de også identificerede sig med fødelandet? Mange mente sagtens, at en dansk og en amerikansk identitet kunne eksistere parallelt, men samfundets pres påvirkede stadig immigranterne og deres debatter.
ENGLEMAGERSKER – MYTE ELLER REALITET?
Authors: Østergaard Schultz Annette
Published: January 2025

Plejebørn i 1800-tallet. Bare disse få ord kan kalde en række billeder frem – billeder fra romaner, erindringer og øjenvidneskildringer i f.eks. samtidens partipolitiske presse. Derfra ved vi, at plejebørn led under uhyggeligt kummerlige forhold. Eller gør vi? Et samfund kan måles på, hvordan det behandler sine svageste. Og ikke mindst siger det noget om et samfunds dominerende menneskesyn, hvis børn i pleje konsekvent blev kynisk udnyttede, hvis de blev hånet, udskældt, mishandlet og i almindelighed gik for lud og koldt vand.
KOMINTERN og de danske kommunister
Authors: Jørgensen Jørgen , Wegener Friis Thomas
Published: January 2025

Arbejdermuseet & ABA, Center for Koldkrigsstudier ved SDU og Det Russiske Statsarkiv for SocioPolitisk Historie har med udgangen af 2013 afsluttet et forsknings- og arkivprojekt om godt 400 danske personsager i Kominterns arkiv, der kaster nyt lys over danskkommunisme og det sovjetiske systems virke.
Drøm og virkelighed på revolutionens fabrikker
Authors: Kulavig Erik
Published: January 2025

Hvilke forestillinger om arbejdet og arbejdets ledelse eksisteredei den russiske offentlighed før og efter revolutionen?I 1920 fandtes der endnu to linjer: Lenins og Trotskijs kommandokurs,hvor arbejderen blev reduceret til produktionskampenssoldat, og oppositionens, hvor disciplinen skullestyrkes gennem samarbejde mellem ledelsen og arbejderne.
Saltofttegninger fra Petrograd 1917 og MoSkva 1927
Authors: Preben-Hansen Bernadette
Published: January 2025

Eduard Saltoft (1883-1939) var en dansk kunstmaler, der arbejdedefor den danske krigsfangehjælp i rusland under verdenskrigen og borgerkrigen.Han boede i Petrograd og var leder af dansk røde kors ilandet fra 1916 til 1918. Under opholdet tegnede og malede han krigens konsekvenserfor befolkningen: sult, sygdomme, nød og død. Saltoft forlod ruslandi 1919 og rejste til london i 1920 for at udstille sine værker fra rusland.
Kold Krig i en dansk køkkenkultur, 1945-65
Authors: Vyff Iben
Published: January 2025

Iben Vyff: The Cold War and the culture of the Danish kitchen, 1945-1965, Arbejderhistorie 2/2012, s. 40-56.For a whole number of years within the field of research on the Cold War there has been a major focus on kitchens and not least the significance of American kitchens as a powerful cultural weapon during this confrontation. For instance most will recall the image ofKhrushchev and Nixon, discussing kitchens in Moscow in 1959. Taking as a point of departure the Danish literature on kitchens produced by architects and other specialists in the field of the kitchen and household/housekeeping, the article investigates the manner in which Danish kitchen culture reflected the Cold War conflict and in what way it is possible to talk about the Cold War in this area of life. The absence of a Soviet impact is therefore discussed. This cannot be explained alone on the basis of the Cold War conflictand deliberations over the American kitchen, but as something in the balance between practical rejection, technological inspiration together with political and symbolic enthusiasm.
Talekor mellem to verdenskrige
Authors: Orsleff Hansen Astrid
Published: January 2025

Astrid Orsleff Hansen, xxx, Arbejderhistorie 2/2012, s. 57-74.From the mid-1920s as an all-encompassing part of its cultural and campaigning work the Danish social democratic youth in the DsUembraced the German speech form of the chant. The chants were a poetic, scenic and collective presentation of the shared wishesand demands of the workers. Together with a whole number of other cultural and agitational forms the chants were to play their part in establishing a special socialist culture aimed at the workers. The idea received its ideological manifestation in Julius Bomholt`s book“Workers` Culture” from 1932, but its practical manifestation was expressed in the cultural initiatives implemented by DsU members in the inter-war years. The chants and the other socialist cultural projects were downgraded with the consensus seeking course the state-bearing (holding governmental power) social democracy presented in the mid-1930s in response to the tense domestic and international political situation. With the slogan “Denmark for the People” the aim was to create a broad popular backing around democracy and the state as a strategy for the survival of the nation, something that was also underpinned culturally. This meant thatthe idea of a specific workers` culture was marginalized also in later history writing. On the basis of ethnographical state and life style theory the spread and meaning of the chants in the DsU during the inter-war years is revealed. The investigation is based on empirical studies. This goes beyond the concept of class, which has typically been used in studies of workers` culture in the inter-war period, to view the field of study in an overall perspective of everyday life, society and state.
Det røde Frederiksberg
Authors: Bro Henning
Published: January 2025

Med et konservativt styre på Frederiksberg siden 1909 skabte det landsdækkende medieopmærksomhed, at denne kronjuvel gled partiet af hænde ved kommunalvalget i 2021. Et vælger- og mandatmæssigt flertal fra Socialdemokratiet, SF, Enhedslisten og Det radikale Venstre samlede sig om en socialdemokrat som borgmester og en radikal som første viceborgmester. Et systemskifte, der naturlig nok rejser en række historiske spørgsmål.
“Tell’em straight what a Strike means”
Authors: Freisleben Lund Nickas
Published: January 2025

Hvad har strejker med litteratur at gøre? En hel del, viser denne artikel, der introducerer en omfattende, men overset moderne litterær tradition: strejkeromanen. En distinkt litterær form, der gestaltes af dens livtag med den historiske strejke. Via analysen af John Steinbecks In Dubious Battle (1936) demonstrerer artiklen, hvordan strejkeromanen tilbyder et perspektivrigt blik på strejkens historie og løber hovedet mod et stadigt presserende spørgsmål: Hvad vil det sige at agere politisk?
Selskabet for Arbejderhistorie fylder 50 år
Authors: Hansen Anette Eklund
Published: January 2025

SFAH har sejret ad helvede til – godt. Arbejdernes historie er blevet en integreret del af Danmarkshistorien. En af feltets nestorer giver i anledning af jubilæet en statusopdatering på selskabets historie.
Ryparkens venner
Authors: Thing Morten
Published: January 2025

Morten Thing: The Friends of Ry Park. Opposition to the inadequate judicial reckoning after the end of the war, Arbejderhistorie3/2012, pp. 95-108.From January 1946 to February 1947 Copenhageners were witnesses to a series of illegal actions, which were focused on drawingattention to the slowness in bringing collaborators with the Germans during the occupation to account. The group, ‘The Friends ofRy Park`, was responsible to a large extent for the actions. Ry Park was the place where the Germans executed members of the resistance. Among others, the group was composed of former resistance fighters who were armed. On the basis of legal documents/papers a history is uncovered and told, which has previously not left a mark in the literature on the occupation.
Promenades littéraires. Arts et détournements de la visite guidée
Authors: Nachtergael Magali
Published: January 2025

Soumis aux mêmes injonctions que les musées, le patrimoine culturel et touristique a développé depuis les années 2000 des stratégies visant à renouveler les récits qui sont associés aux sites remarquables. À travers la fiction, les commandes aux artistes ou aux écrivains, nombre de lieux, villes et régions, ont engagé des mutations narratives et médiatiques. Mais les artistes répondent eux aussi à ces injonctions par des détournements, redéployant le format de la visite guidée de manière créative. À travers les exemples au tournant des années 2010 de Louise Hervé et Clovis Maillet ; Alex Cecchetti, dans le domaine de la performance artistique et narrative (Pireyre, 2022) ; Marcelline Delbecq et Capucine Vever, artistes déléguant la performance à un livre ou à une application d’audioguide, la promenade littéraire invite à se réapproprier l’espace au-delà des surfaces visibles et à réactiver des histoires souterraines, oubliées ou jugées anecdotiques. Le récit permet alors de faire surgir une autre relation avec l’histoire des lieux et l’espace.
Pour une (re)cartographie narrative, autochtone et féministe du territoire urbain : une analyse de Marguerite, la pierre d’Émilie Monnet
Authors: Bradette Marie-Ève
Published: January 2025

Marguerite est une femme autochtone mise en esclavage en Nouvelle-France et ayant eu recours à la justice pour réclamer sa liberté. Le parcours sonore fait ressurgir les mémoires spatiales et remplit les trous laissés béants par l’écriture dominante de l’Histoire. Accompagnés par la voix de Monnet et de ses invités, les auditrices et auditeurs parcourent en effet les rues d’un Montréal (re)cartographié par le récit de Marguerite. Dans cet article, l’autrice suggère que, par la superposition des temporalités et des espaces arpentés, puis par sa réécriture sonore de l’histoire et la réinscription des corps autochtones et racisés sur le territoire montréalais, Monnet crée une (re)cartographie narrative et féministe de Montréal / Tiohtià :ke / Mooniyang qui ébranle les géographies coloniales qui délimitent, encore à l’heure actuelle, les territoires montréalais, québécois et canadien.
La poésie joue dehors : Mes mots, mon quartier et La Rue de la Poésie
Authors: Marcotte Sophie
Published: January 2025

La relation entretenue avec les textes littéraires et le sens qui en est dégagé ont longtemps reposé de manière exclusive sur la lecture en solitaire sur support imprimé qui en est effectuée. Si le livre imprimé rivalise depuis plus de deux décennies avec l’écran, qui a entrainé la modulation des conditions de production et de réception des textes, d’autres phénomènes sont venus modifier le processus de lecture, de validation et de réception des textes littéraires. Ceux-ci ont influencé les pratiques de création et de diffusion dans un autre espace que celui de la page du livre : l’espace public. Cet article, par l’étude de deux projets à dimension interdisciplinaire intitulés Mes mots, mon quartier et La Rue de la poésie, s’intéresse tout particulièrement aux nouvelles modalités de production, de réception et d’interaction du texte littéraire avec l’espace public en milieu urbain. On verra que ces initiatives récentes, fondées sur une participation citoyenne à une expérience de création poétique, contribuent à l’élaboration d’un imaginaire de quartier, et qu’elles participent d’un renouvellement non seulement de la figure de l’autrice ou de l’auteur, mais aussi du rapport traditionnel entre l’individu et l’objet littéraire qui se voit dès lors intégré à un espace communautaire constitué de plusieurs lieux et supports.
Mariposa de sus rayos: un emblema en la música de José de Orejón y Aparicio
Authors: Sacristán Ramírez Carolina
Published: January 2025

La mariposa que vuela alrededor de la llama fue uno de los emblemas más célebres de la Época Moderna. Se utilizó entonces para expresar ideas y emociones asocia­das con la pasión amorosa. Este trabajo analiza dicho emblema desde la cantada Mariposa de sus rayos de José de Orejón y Aparicio cuyo manuscrito perteneció al repertorio de la Catedral de Lima en el siglo XVIII. La obra sirve como punto de partida para recuperar el mito griego que origina el emblema, su diseminación mediante imágenes que circularon en el ambiente cortesano europeo, su reinterpretación según la mística católica y, finalmente, su transposición al lenguaje de la música basada en la retórica de los afectos. Así, el estudio llama la atención sobre sobre esta forma de expresión musical como una manifestación que debe estudiarse profundamente todavía.
Un César para los territorios daneses: Isabel de Portugal, Dorotea de Dinamarca y la conquista báltica
Authors: Soler Moratón Melania
Published: January 2025

El presente trabajo pretende examinar la medalla del Triunfo del César en posesión de Isabel de Avis. Enseña hoy perdida, conocemos de su existencia gracias al in­ventario post-mortem de la Emperatriz. Obra de gran calidad, su descripción nos informa de su destino: la colección de la princesa Dorotea de Oldemburgo, princesa de Dinamarca y sobrina de Isabel. Obra de fina hechura, este presente post-mortem ejemplificará el papel de las mujeres de la familia en la política expansionista de la dinastía Habsburgo.
Los tipos iconográficos de la tradición cristiana, vol. 9. Antigua Alianza III. El Éxodo, Rafael García Mahíques (dir.), Madrid: Encuentro, 2024, 650 pp.
Authors: Lendínez Tortajada Débora
Published: January 2025

Recensión del libro:
Los tipos iconográficos de la tradición cristiana, vol. 9. Antigua Alianza III. El Éxodo, Rafael García Mahíques (dir.), Madrid: Encuentro, 2024, 650 pp.
Dos mujeres hablan solas. Escritura de vida y conversación en "Borges a contraluz" de Estela Canto
Authors: Bohnhoff Leandro
Published: January 2025

En este trabajo, me propongo leer Borges a contraluz (1989) de Estela Canto desde la perspectiva de las escrituras biográfi cas como forma específi ca de las escrituras de vida. En particular, exploro con detenimiento la relevancia y singularidad que adquiere el vínculo entre biógrafo y biografi ado, y las marcas escriturarias que imprime en la superfi cie textual de la obra. La hipótesis que se pone a prueba en este trabajo postula que uno de los modos en que se articula este vínculo de vidas en la escritura implica no reducir al otro a un tema, sino volverlo un participante vivo de la conversación escrituraria. No (solo) hablar del sujeto biográfi co, sino (sobre todo) hablar con él.
Heel Offloading Posterior Splint for Treatment of Heel Ulcerations
Authors: Hussain Fahad , Lenz Robin
Published: January 2025

Total contact casting is the gold standard for plantar foot ulcers but has been questioned in heel pressure ulcers. Current offloading of heel ulcers is typically removable offloading boots. We describe using a modified posterior splint to offload heel ulcers in nonweightbearing patients. The posterior splint is readily available and familiar to practitioners, with less of a learning curve than a total contact cast. As part of the dressing, the posterior splint is less likely to be removed and leads to increased compliance. We hypothesize that this can translate to improved healing of pressure ulcers at the heel.
Supernumerary Muscles in the Leg and Foot: A Review of Their Types, Frequency, and Clinical Implications
Authors: Ramnani Anushka S. , Landeros Jessica T. , Wedel Mathew , Moellmer Rebecca , Wan Stephen , Shofler David W.
Published: January 2025

Variations of the ankle anatomy are infrequent and exist as supernumerary muscles and tendons. Often understudied and overlooked, their presence can cause many complications of the lower extremity. These muscles, although often asymptomatic, can cause great pain and complications such as tenosynovitis, tarsal tunnel syndrome, lateral ankle instability, and ankle pain when they impinge on the normal anatomy of the patient. The goals of this study were to examine the prevalence of common variants such as the peroneus quartus, peroneus digiti quinti, accessory soleus, flexor accessorius digitorum longus, peroneocalcaneus internus, and tibiocalcaneus internus and to understand the morphological and clinical significance of these accessory muscles and their interactions with surrounding muscles. A literature review of anatomically and clinically based articles was conducted to evaluate the supernumerary muscles. Phrases such as accessory muscles were used to refine the search. Supernumerary muscles have an incidence of 3% to 62%, depending on the muscular compartment and the specific muscle. Although conservative treatments such as orthoses and nonsteroidal anti-inflammatory drugs may help alleviate some pain, surgical treatment yields higher success rates. Identification of supernumerary muscles is mainly by magnetic resonance imaging, but they can be detected by other methods, such as ultrasound. Due to the wide implications of these supernumerary muscles, this study attempted to create a reference guide for physicians to use in aiding their diagnoses and therapeutic plans. Although supernumerary muscles are typically asymptomatic, knowledge of these muscles is beneficial for clinicians in aiding their treatment plans.
UNC-6/Netrin promotes both adhesion and directed growth within a single axon
Authors: Nichols Ev L , Lee Joo , Shen Kang
Published: January 2025

During development axons undergo long-distance migrations as instructed by guidance molecules and their receptors, such as UNC-6/Netrin and UNC-40/DCC. Guidance cues act through long-range diffusive gradients (chemotaxis) or local adhesion (haptotaxis). However, how these discrete modes of action guide axons
in vivo
is poorly understood. Using time-lapse imaging of axon guidance in
C. elegans
, we demonstrate that UNC-6 and UNC-40 are required for local adhesion to an intermediate target and subsequent directional growth. Exogenous membrane-tethered UNC-6 is sufficient to mediate adhesion but not directional growth, demonstrating the separability of haptotaxis and chemotaxis. This conclusion is further supported by the endogenous UNC-6 distribution along the axon’s route. The intermediate and final targets are enriched in UNC-6 and separated by a ventrodorsal UNC-6 gradient. Continuous growth through the gradient requires UNC-40, which recruits UNC-6 to the growth cone tip. Overall, these data suggest that UNC-6 stimulates stepwise haptotaxis and chemotaxis
in vivo
.
Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis
Authors: Outla Zuzana , Oyman-Eyrilmez Gizem , Korelova Katerina , Prechova Magdalena , Frick Lukas , Sarnova Lenka , Bisht Piyush , Novotna Petra , Kosla Jan , Bortel Patricia , Borutzki Yasmin , Bileck Andrea , Gerner Christopher , Rahbari Mohammad , Rahbari Nuh , Birgin Emrullah , Kvasnicova Bibiana , Galisova Andrea , Sulkova Katerina , Bauer Andreas , Jobe Njainday , Tolde Ondrej , Sticova Eva , Rosel Daniel , O’Connor Tracy , Otahal Martin , Jirak Daniel , Heikenwälder Mathias , Wiche Gerhard , Meier-Menches Samuel M , Gregor Martin
Published: January 2025

The most common primary malignancy of the liver, hepatocellular carcinoma (HCC), is a heterogeneous tumor entity with high metastatic potential and complex pathophysiology. Increasing evidence suggests that tissue mechanics plays a critical role in tumor onset and progression. Here we show that plectin, a major cytoskeletal crosslinker protein, plays a crucial role in mechanical homeostasis and mechanosensitive oncogenic signaling that drives hepatocarcinogenesis. Our expression analyses revealed elevated plectin levels in liver tumors, which correlated with poor prognosis for HCC patients. Using autochthonous and orthotopic mouse models we demonstrated that genetic and pharmacological inactivation of plectin potently suppressed the initiation and growth of HCC. Moreover, plectin targeting potently inhibited the invasion potential of human HCC cells and reduced their metastatic outgrowth in the lung. Proteomic and phosphoproteomic profiling linked plectin-dependent disruption of cytoskeletal networks to attenuation of oncogenic FAK, MAPK/Erk, and PI3K/AKT signatures. Importantly, by combining cell line-based and murine HCC models, we show that plectin inhibitor plecstatin-1 (PST) is well-tolerated and potently inhibits HCC progression. In conclusion, our study demonstrates that plectin-controlled cytoarchitecture is a key determinant of HCC development and suggests that pharmacologically induced disruption of mechanical homeostasis may represent a new therapeutic strategy for HCC treatment.
How does chronic pain lead to memory loss?
Authors: Pereira Suelen , Tomsic Ivan , da Costa Robson , Lourenco Mychael V
Published: January 2025

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.
fmo-4 promotes longevity and stress resistance via ER to mitochondria calcium regulation in C. elegans
Authors: Tuckowski Angela M , Beydoun Safa , Kitto Elizabeth S , Bhat Ajay , Howington Marshall B , Sridhar Aditya , Bhandari Mira , Chambers Kelly , Leiser Scott F
Published: January 2025

Flavin-containing monooxygenases (FMOs) are a conserved family of xenobiotic enzymes upregulated in multiple longevity interventions, including nematode and mouse models. Previous work supports that
C. elegans fmo-2
promotes longevity, stress resistance, and healthspan by rewiring endogenous metabolism. However, there are five
C. elegans
FMOs and five mammalian FMOs, and it is not known whether promoting longevity and health benefits is a conserved role of this gene family. Here, we report that expression of
C. elegans fmo-4
promotes lifespan extension and paraquat stress resistance downstream of both dietary restriction and inhibition of mTOR. We find that overexpression of
fmo-4
in just the hypodermis is sufficient for these benefits, and that this expression significantly modifies the transcriptome. By analyzing changes in gene expression, we find that genes related to calcium signaling are significantly altered downstream of
fmo-4
expression. Highlighting the importance of calcium homeostasis in this pathway,
fmo-4
overexpressing animals are sensitive to thapsigargin, an ER stressor that inhibits calcium flux from the cytosol to the ER lumen. This calcium/
fmo-4
interaction is solidified by data showing that modulating intracellular calcium with either small molecules or genetics can change expression of
fmo-4
and/or interact with
fmo-4
to affect lifespan and stress resistance. Further analysis supports a pathway where
fmo-4
modulates calcium homeostasis downstream of activating transcription factor-6 (
atf-6
), whose knockdown induces and requires
fmo-4
expression. Together, our data identify
fmo-4
as a longevity-promoting gene whose actions interact with known longevity pathways and calcium homeostasis.
Correlation of diabetes and adverse outcomes in hospitalized COVID-19 patients admitted to a tertiary hospital in China during a small-scale COVID-19 outbreak
Authors: Li Yu , Li Guanni , Li Jiahong , Luo Zirui , Lin Yaxuan , Lan Ning , Zhang Xiaodan
Published: January 2025

Background

The aim of this study was to investigate the impact of diabetes on mortality and adverse outcomes in COVID-19 patients and to analyse the associated risk factors.

Methods

This is a retrospective cohort study in 500 hospitalized patients with COVID-19 infection (214 with diabetes and 286 without diabetes) admitted to a tertiary hospital in China from December 2022 to February 2023. Demographic information, clinical characteristics and outcomes were collected. Survival status was investigated at discharge and at 6 months after discharge.

Results

The mortality rate of COVID-19 patients with diabetes was higher than the rate of non-diabetic COVID-19 patients, both at discharge, and at 6 months after discharge. Body mass index (BMI), C-reactive protein (CRP), pH, D-dimer, blood osmotic pressure, serum creatinine, white blood cell count, creatine kinase and hospitalization expenses were significantly different between diabetic group and non-diabetic group (p < 0.05). Compared with the survivors, non-survived COVID-19 patients with diabetes had worse diabetes control indicators, with random blood glucose increased by 3.58 mmol/L (p < 0.05), and fasting blood glucose increased by 2.77 mmol/L (p < 0.01). In addition, there were significant differences in age, heart rate, CRP, pH, potassium (K+), serum creatinine, white blood cell count, creatine kinase, the proportion with diabetic complications, treatment in ICU and mechanical ventilation between survivors and non-survivors of COVID-19 patients with diabetes. By multivariate logistic regression analysis, the death of COVID-19 patients with diabetes is positively correlated with age and CRP (p < 0.05), and has a trend towards significance with fasting blood glucose (p < 0.1).

Conclusion

Infection with COVID-19 on the basis of diabetes can significantly increase mortality, which was further associated with diabetes control indicators.
Surgical outcomes in patients with Achilles tendon rupture—a retrospective study
Authors: Kürüm Hüseyin , Tosun Hacı Bayram , Aydemir Faruk , Ayas Orhan , Orhan Kürüm Kübra , İpekten Funda
Published: January 2025

Background

There are two main methods used to treat Achilles tendon rupture (ATR): conservative treatment and surgical intervention. Surgical techniques are divided into three main categories: open surgical repair, mini-open surgical repair, and percutaneous repair (PR). We aimed to compare clinical outcomes in individuals with ATR who were treated with PR, primary repair, and flexor hallucis longus augmentation (FHL-A) with those treated with V-Y plasty and FHL-A.

Methods

The study involved 54 patients who underwent ATR surgical intervention retrospectively. Thirty-two of these were identified as acute and 22 were chronic rupture patients. PR was performed in 32 patients, primary repair and FHL-A in 14 patients, and V-Y plasty and FHL-A in eight patients.

Results

The mean forward jump was 142.69 ± 7.14 cm in individuals who received PR, 137.71 ± 4.51 cm in those who received primary repair + FHL-A, and 123.88 ± 3.09 cm in those who received V-Y plasty + FHL-A (p < 0.001). The decrease in the mean vertical jump distance on the operated side compared to the contralateral extremity was 0.97 ± 0.93, 2.07 ± 0.99, and 3.00 ± 1.69 cm in individuals who underwent PR, primary repair + FHL-A, and V-Y plasty + FHL-A, respectively (p < 0.001). The decrease in the mean dorsiflexion of the operated side ankle compared to the contralateral extremity was found to be 4.34 ± 1.18, 1.93 ± 1.07, and 2.38 ± 0.92 degrees in individuals who underwent PR, primary repair + FHL-A, and V-Y plasty + FHL-A, respectively (p < 0.001).

Conclusion

Although no surgical technique is completely superior to another, better performance tests were observed after PR repair compared to open surgery in individuals involved in sports, but rerupture, dorsiflexion restriction, and painful ankle were disadvantages. FHL-A, which has gained popularity in recent years, showed better performance in tests by contributing to more stable and stronger ankles in sporting individuals with chronic ruptures who had undergone open surgery. FHL-A can be utilized in addition to primary surgical intervention in individuals with high performance expectations before and after injury.