bluuebunny/crossref_metadata_2025 huggingface dataset:
A person-centered perspective on the combined DSM-5 AMPD/ICD-11 personality model: Utility, relationship with the categorical personality disorder model, and capacity to differentiate between levels of identity functioning
Authors: Bastiaens Tim , Bogaerts Annabel , Luyckx Koen , Smits Dirk , Claes Laurence
Published: October 2022

Background

Both the ICD-11 classification of Personality Disorders and the DSM-5 Alternative Model for Personality Disorders (DSM-5 AMPD) conceptualize personality pathology in a dimensional way, but differ in the way they carve up their respective pathological personality domains. Recently, a combination of ICD-11 and DSM-5 AMPD descriptive pathological personality traits, the Modified Personality Inventory for DSM-5—Brief Form Plus (PID5BF + M), was developed.

The current study

We investigated the utility of the additional ANANKASTIA domain (not represented in the DSM-5 AMPD) as well as of the additional PSYCHOTICISM domain (not represented in the ICD-11 model) in the identification of meaningful pathological personality domain clusters based on the PID5BF + M. Next to the classical 2- and 3-cluster solutions, we examined whether the presence of the additional ANANKASTIA domain would also gave rise to a meaningful 4-cluster solution. We then validated these clusters by investigating differences between them in mean DSM-5 Section II cluster A, B, and C personality disorder scores. Finally, we investigated whether cluster membership was able to differentiate between levels of identity functioning, a key feature of personality disorder severity in both the ICD-11 model and the DSM-5 AMPD.

Materials and methods

We used a Flemish community sample of 242 participants, and applied k-means cluster analyses in a two-step manner on PID5BF + M domains to investigate 2-, 3-, and 4-cluster solutions. We used MANOVAs to examine differences between clusters in PID5BF + M domains, DSM-IV/DSM-5 Section II Assessment of Personality disorders (ADP-IV) cluster A, B, and C scores, and Self-Concept and Identity Measure (SCIM) scores.

Results

Cluster analyses on PID5BF + M pathological personality domains (1) revealed meaningful 2-, 3-, and 4-cluster solutions, with the 4-cluster solution explaining the most variance in the clustering variables, (2) allowed to identify a classical Overcontrolled cluster which DSM-5 AMPD PID-5 does not, and (3) demonstrated the utility of representing ANANKASTIA and DISINHIBITON as separate pathological personality domains. PID5BF + M clusters (5) were informative of DSM-5 Section II cluster A, B, and C personality disorder scores and (6) showed different levels of clinical-developmental Identity functioning.

Conclusion

Current results demonstrate the utility of a combined ICD-11/DSM-5 AMPD view from a person-centered perspective.
The proportion of HIV disclosure to sexual partners among people diagnosed with HIV in China: A systematic review and meta-analysis
Authors: Peng Wenwen , Song Xiaohan , Zhang Ci , Chen Yuqing , Zhou Qidi , Välimäki Maritta Anneli , Li Xianhong
Published: October 2022

Background

Sexual behavior is one of the main routes of HIV/AIDS spread. HIV disclosure to sexual partners has been confirmed to be an important strategy for HIV/AIDS prevention and control. We conducted a systematic review and meta-analysis to pool proportions and characteristics of HIV disclosure to sexual partners among people diagnosed with HIV in China.

Methods

We searched eight databases and extracted the data on HIV disclosure to partners. Heterogeneity of the data was tested with I2. Published bias subjectively and objectively analyzed through the funnel plot and Egger's regression test. Subgroup analyses were performed to explore the variation in the proportion by sexual partnership types (unclassified, regular, casual sexual partners), whether being men who have sex with men (MSM), and when to diagnose. The sources of heterogeneity were analyzed. Sensitivity analysis was carried out to evaluate the stability of the results.

Results

Out of 3,698 studies, 44 were included in the review; 11 targeted on MSM. The pooled proportion of HIV disclosure to sexual partners was 65% (95% CI: 56%−75%; 34 studies). Sub-group analyses indicated the proportions of HIV disclosure to regular, casual and unclassified sexual partners were 63% (95% CI: 45%−81%; 31 studies), 20% (95% CI: 8%−33%; nine studies), and 66% (95% CI: 59%−73%; 14 studies), respectively. Fifty-seven percent (95% CI: 45%−69%; three studies) disclosed on the day of diagnosis, 62% (95% CI: 42%−82%; four studies) disclosed within 1 month, and 39% (95% CI: 2%−77%; four studies) disclosed 1 month later. Among MSM, the disclosure to regular male partners, regular female sexual partners, spouses, and casual partner were 47% (95% CI: 29%−65%; six studies), 49% (95% CI: 33%−65%; three studies), 48% (95% CI: 18%−78%; seven studies), and 34% (95% CI: 19%−49%; four studies), respectively.

Conclusions

The disclosure prevalence of people diagnosed with HIV to sexual partners still need improving in China, and it varies among partner types, key populations, and time being diagnosed. HIV disclosure strategies and procedures need to be developed more detailed and tailored based on the pain points of disclosure status, so as to ultimately prevent HIV transmission through sexual contact.

Systematic review registration

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022291631, identifier: CRD42022291631.
Association of in vitro fertilization with maternal and perinatal outcomes among pregnant women with active tuberculosis: A retrospective hospital-based cohort study
Authors: Xia Lu , Mijiti Peierdun , Liu Xu-Hui , Hu Zhi-Dong , Fan Xiao-Yong , Lu Shui-Hua
Published: October 2022

Background

Study on effect of fertilization methods on maternal and perinatal outcomes with respect to TB during pregnancy was scarce. This study aimed to analyze maternal and perinatal outcomes in active TB cases after in vitro fertilization (IVF) treatment vs. normal pregnancy.

Methods

Clinical data of 80 pregnant women with active TB hospitalized at Shanghai Public Health Clinical Center between June 1st, 2014 and November 30th, 2020 were extracted and retrospectively analyzed. History of receiving IVF was recorded at admission and its association with maternal and perinatal outcomes were assessed using multivariable logistic regression models with adjustment for potential confounders.

Results

Of the 80 pregnant women with active TB, 28 (35.0%) received IVF treatment and 52 (65.0%) did not receive IVF treatment. After adjusting for potential confounders, receiving IVF was associated with worse maternal and perinatal outcomes, including maternal criticality (21.4 vs. 2.0%, adjusted OR = 28.3, P = 0.015), miliary TB (89.3 vs. 13.5%, adjusted OR = 75.4, P < 0.001), TB meningitis (32.1 vs. 7.7%, adjusted OR = 6.2, P = 0.010), and perinatal mortality (64.3 vs. 28.8%, adjusted OR = 9.8, P = 0.001).

Conclusion

The additional risk of TB to women receiving IVF treatment is a public health challenge specific to countries with a high tuberculosis burden. Increased awareness of latent tuberculosis infection in women receiving IVF treatment is needed.
Learning from the COVID-19 pandemic for future epidemics and pandemics preparedness and response in Guinea: Findings from a scoping review
Authors: Kolié Delphin , Keita Fatoumata Namaren , Delamou Alexandre , Dossou Jean-Paul , Van Damme Wim , Agyepong Irene Akua
Published: October 2022

The outbreak of the novel coronavirus (SARS-CoV-2) in December 2019 prompted a response from health systems of countries across the globe. The first case of COVID-19 in Guinea was notified on 12 March 2020; however, from January 2020 preparations at policy and implementation preparedness levels had already begun. This study aimed to assess the response triggered in Guinea between 27th January 2020 and 1st November 2021 and lessons for future pandemic preparedness and response. We conducted a scoping review using three main data sources: policy documents, research papers and media content. For each of these data sources, a specific search strategy was applied, respectively national websites, PubMed and the Factiva media database. A content analysis was conducted to assess the information found. We found that between January 2020 and November 2021, the response to the COVID-19 pandemic can be divided into five phases: (1) anticipation of the response, (2) a sudden boost of political actions with the implementation of strict restrictive measures, (3) alleviation of restrictive measures, (4) multiple epidemics period and (5) the COVID-19 variants phase, including the strengthening of vaccination activities. This study provides several learning points for countries with similar contexts including: (1) the necessity of setting up, in the pre-epidemic period, an epidemic governance framework that is articulated with the country's health system and epidemiological contexts; (2) the importance of mobilizing, during pre-epidemic period, emergency funds for a rapid health system response whenever epidemics hit; (3) each epidemic is a new experience as previous exposure to similar ones does not necessarily guarantee population and health system resilience; (4) epidemics generate social distress because of the restrictive measures they require for their control, but their excessive securitization is counterproductive. Finally, from a political point of view, decision-making for epidemic control is not always disinterested; it is sometimes rooted in political computations, and health system actors should learn to cope with it while, at the same time, safeguarding trusted and efficient health system responses. We conclude that health system actors anticipated the response to the COVID-19 pandemic and (re-) adapted response strategies as the pandemic evolved in the country. There is a need to rethink epidemics governance and funding mechanisms in Guinea to improve the health system response to epidemics.
Hierarchical medical system and local medical performance: A quasi-natural experiment evaluation in Shanghai, China
Authors: Liang Chen , Zhao Yihang , Yu Chenglong , Sang Peng , Yang Long
Published: October 2022

Background

In order to maintain high standards of healthcare, it is necessary for medical departments to provide high-quality and affordable medical services to local residents. This has been widely accepted in developed countries, while the medical treatment systems in developing countries remain to be improved. This research is based on a pilot of a hierarchical medical system in Shanghai, China, to evaluate the effects on policy of medical reform in developing countries.

Methods and results

By means of the difference-in-differences (DID) method, the causal relationship between medical care services' improvement and hierarchical medical systems' implementation could be identified. This project also explores the differential effects of policy intervention and confirms that the pilot showed a significant improvement in medical performance in central districts while the result remains uncertain in terms of suburban districts. Furthermore, the dynamic effect of a hierarchical medical system has also been identified with the event study method, while the policy pilot only had short-term effects on local medical resources' improvement. In order to ascertain the function mechanisms of hierarchical medical systems and explain why the policy pilot only had short-term effects, this project also conducts influencing mechanism analysis with the triple-differences method (also known as difference-in-difference-in-differences or DDD method). According to the empirical results, there is no direct evidence indicating the hierarchical medical system could bring obvious benefits from the perspectives of patients and medical institutions.

Conclusions

For better implementation of hierarchical medical systems in the future, long-term supervision mechanisms should be given more attention in the enforcement process of hierarchical medical systems. At the same time, more safeguarding measures should be implemented, such as supervising the payment systems of the medical institution and conducting performance evaluation.
Factors influencing patients' opt-in intention of exchanging health information
Authors: Zhang Xijing , Zhang Runtong
Published: October 2022

Introduction

Health information exchange (HIE) exhibits tremendous benefits in improving the quality of healthcare and reducing healthcare costs. However, it also poses challenges related to data security, data privacy, patient engagement, etc.

Objective

This study aimed to explore the factors affecting patients' opt-in intention to HIE by using an empirical study based on the theory of planned behavior.

Methods

A Web-based survey was conducted involving 501 valid participants in China (69% validity rate).

Results

Information sensitivity and perceived HIE transparency affected the patients' opt-in intention to HIE through the mediation of perceived behavior control and trust in HIE. Information sensitivity negatively influenced perceived behavior control (−0.551, P < 0.001) and trust in HIE (−0.489, P < 0.001). Perceived transparency of HIE positively influenced perceived behavior control (0.396, P < 0.001) and trust in HIE (0.471, P < 0.001). Moreover, patients' opt-in intention to HIE can be positively affected by perceived HIE transparency (0.195, P < 0.001) and trust in HIE (0.294, P < 0.001). In addition, the moderating effect of health status was positive and significant between trust in HIE and opt-in intention to HIE but not between the perceived behavior control and opt-in intention to HIE.

Conclusion

This study contributes to the theory of planned behavior and enriches the literature on HIE efforts. HIE administrators should design personalized health services on the basis of these different health statuses to successfully achieve patients' opt-in intention to HIE.
Consumer perspectives on grab bars: A Canadian national survey of grab bar acceptability in homes
Authors: Levine Iris C. , Lau Sin-Tung , King Emily C. , Novak Alison C.
Published: October 2022

Given the prevalence and severity of bathroom falls and injuries across age groups, there is growing interest in policy-level approaches to bathroom fall prevention. Grab bars reduce fall risk during bathing transfers and improve bathing accessibility for adults of all ages and abilities. However, they are frequently absent from bathing environments, even in the homes of individuals who have a specific need for a grab bar. While mandatory bathroom grab bar installation has been suggested, it is unclear whether this would be supported by Canadians. The purpose of this study was to characterize Canadian public perceptions on the installation and use of grab bars in home bathrooms. We surveyed 443 Canadians about whether they currently had a grab bar and their perspectives on grab bar policy. 65.4% of respondents did not have a grab bar. However, 88.5% of respondents would allow a grab bar to be installed in their bathroom at no cost to them, only 11.5% of respondents would object to grab bar installation becoming mandatory in new builds, and 85.6% of respondents would use a grab bar if it were installed in their bathroom. Responses were affected by age (in four groups: 18–39, 40–59, 60–79, and 80+ years), self-reported impairment, and home ownership status. Older adults, respondents who reported having impairments, and home owners were more likely to respond favorably toward grab bars. Based on these results, the majority of Canadians would respond positively to policy mandating bathroom grab bars in new homes.
Age-related circadian rhythm and variability of large- and small-airway function in healthy non-smoking adults: Data from 7-day diurnal and nocturnal home monitoring using an electronic portable spirometer
Authors: Zhang Xue , Zhang Yingying , Zhou Yan , Yin Dongning , Lv Chengjian , Lin Jinwang , Bao Wuping , Zhang Min
Published: October 2022

Background

The aim of the study was to investigate the possible influencing factors of the large- and small-airway function variation in healthy non-smoking adults.

Methods

Healthy non-medical non-smoking adults were enrolled in this prospective cohort study. Each participant took the portable spirometer test relying only on video teaching. Then conventional spirometry and bronchodilation test were conducted using a Jaeger spirometer, followed by 7-day diurnal and nocturnal home monitoring using a portable spirometer.

Results

A drop in both large- and small-airway function began at about 25 years of age, and a rapidly decline at about 50 years. The CV of FEV1 (r = 0.47, P = 0.0082) and small-airway function variables correlated with age (r ≥ 0.37, P < 0.05 for both MEFs and MEFs/FVC), especially for evening small-airway function variables. The CV of large (4.666 ± 1.946, P = 0.002 for FEV1; 4.565 ± 2.478, P = 0.017 for FEV3) and small airways (10.38 ± 3.196, P = 0.031 for MEF50 and 11.21 ± 4.178, P = 0.023 for MMEF) was higher in the 45- to 60-year subgroup than in the 30- to 45-year and 18- to 30-year subgroups.

Interpretation

Age was the main influencing factor of both central and peripheral airway function variability, especially for the small-airway function in the evening. The LLN of small-airway variables varies depending on the age and circadian rhythm. People older than 45 years should pay more attention to monitoring small-airway function in the evening, which will be helpful for early clinical detection of those at high risk for asthma.

Trial registration number

ChiCTR2100050355.
Application of clinical nomograms to predicting overall survival and event-free survival in multiple myeloma patients: Visualization tools for prognostic stratification
Authors: Xu Jiaxuan , Zuo Yifan , Sun Jingjing , Zhou Min , Dong Xiaoqing , Chen Bing
Published: October 2022

Background

This study aimed to develop reliable nomogram-based predictive models that could guide prognostic stratification and individualized treatments in patients with multiple myeloma (MM).

Methods

Clinical information of 560 patients was extracted from the MM dataset of the MicroArray Quality Control (MAQC)-II project. The patients were divided into a development cohort (n = 350) and an internal validation cohort (n = 210) according to the therapeutic regimens received. Univariate and multivariate Cox regression analyses were performed to identify independent prognostic factors for nomogram construction. Nomogram performance was assessed using concordance indices, the area under the curve, calibration curves, and decision curve analysis. The nomograms were also validated in an external cohort of 56 patients newly diagnosed with MM at Nanjing Drum Tower Hospital from May 2016 to June 2019.

Results

Lactate dehydrogenase (LDH), albumin, and cytogenetic abnormalities were incorporated into the nomogram to predict overall survival (OS), whereas LDH, β2-microglobulin, and cytogenetic abnormalities were incorporated into the nomogram to predict event-free survival (EFS). The nomograms showed good predictive performances in the development, internal validation, and external validation cohorts. Additionally, we observed a superior prognostic predictive ability in nomograms compared to that of the International Staging System. According to the prognostic nomograms, risk stratification was applied to divide the patients into two risk groups. The OS and EFS rates of low-risk patients were significantly better than those of high-risk patients, suggesting a greater function of the nomogram models for risk stratification.

Conclusion

Two simple-to-use prognostic models were established and validated. The proposed nomograms have potential clinical applications in predicting OS and EFS for patients with MM.
Point-of-care detection of SARS-CoV-2 antigen among symptomatic vs. asymptomatic persons: Testing for COVID-19 vs. infectivity
Authors: Neukam Karin , Lucero Alicia , Gutiérrez-Valencia Alicia , Amaya Lucas , Echegoyen Natalia , Martelli Antonella , Videla Cristina , Di Lello Federico A. , Martínez Alfredo P.
Published: October 2022

Background

Management of the coronavirus disease 2019 (COVID-19) pandemic caused by a novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requires rapid and simple methods to detect COVID-19 patients and identify potential infectors. This study aimed to evaluate the utility of a point-of-care (PoC) rapid antigen diagnostic test (Ag-RDT) in these settings.

Patients and methods

Individuals who consecutively presented for SARS-CoV-2 testing at a tertiary care center in Buenos Aires, Argentina, underwent PoC Ag-RDT testing and real-time RT-PCR (qRT-PCR) on the same day during June 2021.

Results

Of 584 included subjects, 108 (18.5%) were symptomatic for COVID-19 while the remaining presented for miscellaneous reasons unrelated to possible or confirmed contact with a SARS-CoV-2-infected individual. A positive Ag-RDT result was obtained in 26 (24.1%) symptomatic and 7 (1.5%) asymptomatic persons (p < 0.001), which was concordant with qRT-PCR in 105/108 [97.2%, Cohen's kappa coefficient (κ) = 0.927] symptomatic and 467/476 (98.1% κ = 0.563) asymptomatic participants, with a positive percentage agreement (PPA; 95% confidence interval) of 89.7% (71.5–97.3%) and 42.9% (18.8–70.4%), respectively. None of the 11 false-negative diagnoses showed a Ct-value ≤20. Considering only failures with a Ct-value below 31 as hypothetical infectivity threshold of 105 SARS-CoV-2 RNA copies/mL, concordance was observed in 98.1% (κ = 0.746) in the asymptomatic population, accounting for a PPA of 66.7% (30.9–91%).

Conclusions

PoC Ag-RDT accurately detected active SARS-CoV-2 infection and showed acceptable diagnostic performance in asymptomatic persons potentially spreading infectious virus. Ag-RDT may therefore be useful to slow down or stop transmission by enabling adequate decisions on isolation at a public health level.
Development of dialogue system architecture toward co-creating social intelligence when talking with a partner robot
Authors: Fujii Ayaka , Jokinen Kristiina , Okada Kei , Inaba Masayuki
Published: October 2022

Social robots have grown increasingly integrated into our daily lives in recent years. Robots can be good social agents who engage with people, such as assistants and counselors, and good partners and companions with whom people can form good relationships. Furthermore, unlike devices such as smart speakers or virtual agents on a screen, robots have physicality, which allows them to observe the actual environment using sensors and respond behaviorally with full-body motions. In order to engage people in dialogue and create good relationships with robots as close partners, real-time interaction is important. In this article, we present a dialogue system platform developed with the aim of providing robots with social skills. We also built a system architecture for the robot to respond with speech and gestures within the dialogue system platform, which attempts to enable natural engagement with the robot and takes advantage of its physicality. In addition, we think the process called “co-creation” is important to build a good human–robot interaction system. Engineers must bridge the gap between users and robots in order for them to interact more effectively and naturally, not only by building systems unilaterally but also from a range of views based on the opinions of real users. We reported two experiments using the developed dialogue interaction system with a robot. One is an experiment with elderly people as the initial phase in this co-creation process. The second experiment was conducted with a wide range of ages, from children to adults. Through these experiments, we can obtain a lot of useful insights for improving the system. We think that repeating this co-creation process is a useful approach toward our goal that humans and robots can communicate in a natural way as good partners such as family and friends.
Dynamics and control analysis during rendezvous in non-Keplerian Earth—Moon orbits
Authors: Innocenti Mario , Bucchioni Giordana , Franzini Giovanni , Galullo Michele , Onofrio Fabio D’ , Cropp Alexander , Casasco Massimo
Published: October 2022

The paper describes the development of a framework capable of addressing some fundamental issues in the analysis of proximity operations between two spacecraft that are operating within a three-body model defined by two primaries and the spacecraft themselves. The main objective is to enable the capability of analysing dynamic and control issues during an automated rendezvous between a vehicle and a passive space station orbiting around the Earth - Moon L2 Lagrangian point on a near rectilinear halo orbit. The paper presents first a restricted three body model dynamics and a nominal approach trajectory, followed by an analysis of the influence of assumed actuators and sensors. Critical aspects such as selected failures are investigated, in order to ensure passive safety of the mission using impulsive maneuvers. An example of closed loop guidance in the near range is also presented and the overall performance are validated with an Ephemeris model available in the literature.
Investigation of the improving effect of raw and charred hawthorn on functional dyspepsia based on interstitial cells of Cajal
Authors: Ai Li , Zhang Lilin , Liang Qi , Tian Yao , Chen Tao , Wu Chunjie
Published: October 2022

Background

Raw hawthorn (RH) is a traditional Chinese medicine commonly used to treat indigestion. Charred hawthorn (CH) is obtained from RH by charring. It is reported that the effect of CH treatment on dyspepsia is stronger than RH. However, this has not been fully proven. The purpose of this study was to compare the effects of RH and CH on functional dyspepsia (FD) model rats. And contribute to the development of dietary therapy for dyspepsia.

Methods

SPF-grade male SD rats were divided into 5 groups: the control group, the model group, the Mos group, the RH group, and the CH group. The FD rat model was established by using the methods of water restriction, fasting, tilting cage restraint, day and night upside down, swimming, and tail damping. The body weight of rats in each group was recorded. And the gastric emptying rate, intestinal propulsive rate, and the levels of motilin (MTL), gastrin (GAS), and 5-HT in serum were compared in each group. The expression of C-kit in the stomach and small intestine of each group was compared by immunofluorescence and PCR.

Results

RH and CH could increase weight, improve the gastric emptying rate and intestinal propulsive rate, and promote the secretion of motilin (MTL), gastrin (GAS), and 5-HT in the serum of FD rats. RH and CH can upregulate the expression of the characteristic protein c-kit of ICC in the stomach and small intestine of FD model rats, and the effect of CH is stronger than RH.

Conclusion

RH and CH may increase the number of interstitial cells of Cajal (ICC) in the gastrointestinal tract by upregulating c-kit expression, thus improving gastrointestinal motility in FD model rats. And compared with RH, CH has certain advantages.
Hemodynamic alterations with large spontaneous splenorenal shunt ligation during adult deceased donor liver transplantation
Authors: Chen Guangshun , Li Qiang , Zhang Zhongqiang , Xie Bin , Luo Jing , Si Zhongzhou , Li Jiequn
Published: October 2022

Background

A large spontaneous splenorenal shunt (SRS) will greatly impact portal inflow to the graft during liver transplantation (LT). Direct ligation of a large SRS is an uncommon surgical procedure and the hemodynamic consequences of this procedure are unknown.

Methods

In this retrospective study, we described our technique for direct ligation of a large SRS and the consequent hemodynamic changes during LT. 3-Dimensional computed tomography and Doppler ultrasonography were used to evaluate SRS and portal vein blood flow volume (PFV).

Results

A total of 22 recipients had large SRS including 13 with PFV <85 ml/min/100 g (ligation group) and 9 with PFV ≥85 ml/min/100 g (no ligation group). The diameter of SRS was significantly larger in the ligation group than in the non-ligation group (22.92 ± 4.18 vs. 16.24 ± 3.60 mm; p = 0.0009). In all ligation patients, the SRS was easily identified and isolated, it was located just below the distal pancreas and beside the inferior mesenteric vein. PV flow increased significantly from 68.74 ± 8.77 to 116.80 ± 16.50 ml/min/100 g (p < 0.0001) after ligation; this was followed by a reduction in peak systolic velocity of the hepatic artery from 58.17 ± 14.87 to 46.67 ± 13.28 cm/s (p = 0.0013).

Conclusions

Direct ligation of large SRS was an effective and safe surgical procedure to overcome the problem of portal hypoperfusion during LT.
The oral vaccination with Paenibacillus larvae bacterin can decrease susceptibility to American Foulbrood infection in honey bees—A safety and efficacy study
Authors: Dickel Franziska , Bos Nick Maria Peter , Hughes Huw , Martín-Hernández Raquel , Higes Mariano , Kleiser Annette , Freitak Dalial
Published: October 2022

Pollination services to increase crop production are becoming more and more important, as we are facing both climate change and a growing world population. Both are predicted to impact food security worldwide. High-density, commercial beekeeping has become a key link in the food supply chain, and diseases have become a central issue in hive losses around the world. American Foulbrood (AFB) disease is a highly contagious bacterial brood disease in honey bees (Apis mellifera), leading to hive losses worldwide. The causative agent is the Gram+ bacterium Paenibacillus larvae, which is able to infect honey bee larvae during the first 3 days of their lives. It can be found in hives around the world with viable spores for decades. Antibiotics are largely ineffective in treating the disease as they are only efficient against the vegetative state. Once a hive shows the clinical manifestation of the disease, the only effective way to eradicate it and prevent the spread of the disease is by burning the hive, the equipment, and the colony. Because of its virulent nature and detrimental effects on honey bee colonies, AFB is classified as a notifiable disease worldwide. Effective, safe, and sustainable methods are needed to ensure the wellbeing of honey bee colonies. Even though insects lack antibodies, which are the main requisites for trans-generational immune priming (TGIP), they can prime their offspring against persisting pathogens. Here, we demonstrate an increased survival of infected honey bee larvae after their queen was vaccinated, compared to offspring of control queens (placebo vaccinated). These results indicate that TGIP in insects can be used to majorly enhance colony health, protect commercial pollinators from deadly diseases, and reduce high financial and material losses to beekeepers.

Classification

biological sciences, applied biological sciences
A Multi-Hook Control Strategy for a Semi-Active Device Combining an Adjustable Inerter and Damper
Authors: Zhang Xiaoliang , Zhang Yimu , Zhao Yue , Nie Jiamei
Published: October 2022

Neither the separate skyhook damping nor the skyhook inertance control strategy can adapt to the variations of both road and load conditions simultaneously. To address this issue, this work proposed a novel ideal multi-hook system by combining the skyhook inerter and hybrid damper, with both of their coefficients optimized. The proposed system can achieve road holding without sacrificing ride comfort. Depending on whether the inerter and damper were adjusted independently or together, this ideal multi-hook was realized semi-actively in two different control models with three different control strategies, i.e., independent, inertance-based and damping-based control. The effects of these strategies were compared and analyzed. The simulation results show that compared with passive suspension, the root mean square value of body acceleration of the three kinds of multi-hook suspension decreases by more than 40% under different loads and by more than 28% on the roads of Classes A, B and C. Compared with the skyhook damping suspension, the dynamic wheel load of the multi-hook suspensions is reduced by more than 27.5%, proving that the semi-active suspension system with multi-hook control guarantees handling stability under various road and load conditions while ensuring ride comfort.
Aerodynamic Characteristics of Bristled Wings in Flapping Flight
Authors: Shen Tong , Tu Zhan , Li Daochun , Kan Zi , Xiang Jinwu
Published: October 2022

This study focuses on the aerodynamics of the smallest flying insects’ bristled wings. We measured and analyzed wing morphological data from 38 specimens of Mymaridae. Bristled wing flight was numerically simulated at Reynolds numbers from 1 to 80. The aerodynamic force, power, and efficiency of bristled wings using lift-based stroke, drag-based stroke, and clap-and-fling mechanism were evaluated. An unusual clap-and-fling pattern considering bristle crossing was first proposed. Our study shows that with a reduction in the wingspan of Mymaridae, the proportion of the wingtip bristled area increases. A lift-based stroke is superior to a drag-based stroke in terms of vertical force production and aerodynamic efficiency at 5 ≤ Re ≤ 20. Bristled wings employing the clap-and-fling mechanism achieve both vertical force and efficiency augmentation, while bristle crossing incurs a substantial horizontal force and contributes little to vertical force augmentation.
Earthwork Volume Calculation, 3D Model Generation, and Comparative Evaluation Using Vertical and High-Oblique Images Acquired by Unmanned Aerial Vehicles
Authors: Lee Kirim , Lee Won Hee
Published: October 2022

In civil engineering and building construction, the earthwork volume calculation is one of the most important factors in the design and construction stages; therefore, an accurate calculation is necessary. Moreover, because managing earthworks is highly important, in this study, a three-dimensional (3D) model for earthwork calculation and management was performed using an unmanned aerial vehicle (UAV) and an RGB camera. Vertical and high-oblique images (45°, 60°, and 75°) were acquired at 50 and 100 m heights for accurate earthwork calculations and a 3D model, and data were generated by dividing the images into eight cases. Cases 1–4 were images acquired from a height of 50 m, and cases 5–8 were images acquired from a height of 100 m. (case 1: 90°, case 2: 90° + 45°, case 3: 90° + 60°, case 4: 90° + 75°, case 5: 90°, case 6: 90° + 45°, case 7: 90° + 60°, case 8: 90° + 75°). Three evaluations were performed on the data. First, the accuracy was evaluated through checkpoints for the orthophoto; second, the earthwork volumes calculated via a global positioning system and UAV were compared; finally, the 3D model was evaluated. Case 2, which showed the lowest root mean square error in the orthophoto accuracy evaluation, was the most accurate. Case 2 was the most accurate in the earthwork volume evaluation and 3D model compared to other cases. Through this study, the best results were obtained when using a vertical image and a high-oblique image of 40 to 50° when generating a 3D model for earthwork volume calculation and management. In addition, if the UAV is not affected by obstacles, it is better to shoot at about 50 m or less than to shoot the UAV height too high.
Heat Conduction and Microconvection in Nanofluids: Comparison between Theoretical Models and Experimental Results
Authors: Bovesecchi Gianluigi , Corasaniti Sandra , Costanza Girolamo , Piccotti Fabio , Potenza Michele , Tata Maria Elisa
Published: October 2022

A nanofluid is a suspension consisting of a uniform distribution of nanoparticles in a base fluid, generally a liquid. Nanofluid can be used as a working fluid in heat exchangers to dissipate heat in the automotive, solar, aviation, aerospace industries. There are numerous physical phenomena that affect heat conduction in nanofluids: clusters, the formation of adsorbate nanolayers, scattering of phonons at the solid–liquid interface, Brownian motion of the base fluid and thermophoresis in the nanofluids. The predominance of one physical phenomenon over another depends on various parameters, such as temperature, size and volume fraction of the nanoparticles. Therefore, it is very difficult to develop a theoretical model for estimating the effective thermal conductivity of nanofluids that considers all these phenomena and is accurate for each value of the influencing parameters. The aim of this study is to promote a way to find the conditions (temperature, volume fraction) under which certain phenomena prevail over others in order to obtain a quantitative tool for the selection of the theoretical model to be used. For this purpose, two sets (SET-I, SET-II) of experimental data were analyzed; one was obtained from the literature, and the other was obtained through experimental tests. Different theoretical models, each considering some physical phenomena and neglecting others, were used to explain the experimental results. The results of the paper show that clusters, the formation of the adsorbate nanolayer and the scattering of phonons at the solid–liquid interface are the main phenomena to be considered when φ = 1 ÷ 3%. Instead, at a temperature of 50 °C and in the volume fraction range (0.04–0.22%), microconvection prevails over other phenomena.
Aerodynamic Data-Driven Surrogate-Assisted Teaching-Learning-Based Optimization (TLBO) Framework for Constrained Transonic Airfoil and Wing Shape Designs
Authors: Wu Xiaojing , Zuo Zijun , Ma Long
Published: October 2022

The surrogate-assisted optimization (SAO) process can utilize the knowledge contained in the surrogate model to accelerate the aerodynamic optimization process. The use of this knowledge can be regarded as the primary form of intelligent optimization design. However, there are still some difficulties in improving intelligent design levels, such as the insufficient utilization of optimization process data and optimization parameters’ adjustment that depends on the designer’s intervention and experience. To solve the above problems, a novel aerodynamic data-driven surrogate-assisted teaching-learning-based optimization (TLBO) framework is proposed for constrained aerodynamic shape optimization (ASO). The main contribution of the study is that ASO is promoted using historically aerodynamic process data generated during the gradient free optimization process. Meanwhile, nonparametric adjustment of the TLBO algorithm can help relieve manual design experience for actual engineering applications. Based on the structure of the TLBO algorithm, a model optimal prediction method is proposed as the new surrogate-assisted support strategy to accelerate the ASO process. The proposed method is applied to airfoil and wing shape designs to verify the optimization effect and efficiency. A benchmark aerodynamic design optimization is employed for the drag minimization of the RAE2822 airfoil. The optimized results indicate that the proposed method has advantages of high efficiency, strong optimization ability, and nonparametric characteristics for ASO. Moreover, the results of the wing shape optimization verify the advantages of the proposed methods over the surrogate-based optimization and direct optimization frameworks.
High-Throughput Phenotyping of Cross-Sectional Morphology to Assess Stalk Mechanical Properties in Sorghum
Authors: Fan Hongzeng , Wang Jibin , Shen Songhao , Yang Mingchong , Li Suli , Feng Bihong , Zhong Ruimin , Ma Chongjian , Wang Jihong , Xie Ruohan , Wang Lingqiang
Published: October 2022

Lodging is one of the major constraints in attaining high yield in crop production. Major factors associated with stalk lodging involve morphological traits and anatomical features along with the chemical composition of the stem. However, little relevant research has been carried out in sorghum, particularly on the anatomical aspects. In this study, with a high-throughput procedure newly developed by our research group, the nine parameters related to stem regions and vascular bundles were generated in 58 sorghum germplasm accessions grown in two successive seasons. Correlation analysis and principal component analysis were conducted to investigate the relationship between anatomical aspects and stalk mechanical traits (breaking force, stalk strength and lodging index). It was found that most vascular parameters were positively associated with breaking force and lodging index with the correlation coefficient r varying from −0.46 to 0.64, whereas stalk strength was only associated with rind area with the r = 0.38. The germplasm resources can be divided into two contrasting categories (classes I with 23 accessions and II with 30 accessions). Compared to class II, the class I was characterized by a larger number (+40.7%) and bigger vascular bundle (+30%), thicker stem (+19.6%) and thicker rind (+36.0%) but shorter internode (plant) (−91.0%). This study provides the methodology and information for the studies of the stem anatomical parameters in crops and facilitates the selective breeding of sorghum.
Bio-Stimulants Extend Shelf Life and Maintain Quality of Okra Pods
Authors: El-Shaieny Abdel-Haleem A. H. , Abd-Elkarim Naglaa A. A. , Taha Eman M. , Gebril Sayed
Published: October 2022

Okra (Abelmoschus esculentus L.), a tropical annual crop, is a highly perishable vegetable. Okra pods deteriorate rapidly after harvesting. The pods undergo physical and physiological changes that diminish storability and quality. The purpose of this study was to investigate the effect of bio-stimulants on the storability and quality of okra pods stored at 4 °C and 25 °C for 12 days. Dipping okra pods for 5 min in a solution of 0.5% ascorbic acid, citric acid, or salicylic acid pre-storage significantly extended the shelf life and preserved the quality of the pods compared to the control condition at 4 °C and 25 °C. Citric acid and ascorbic acid were the most effective in preserving most traits. Citric acid reduced the loss in weight, firmness, appearance, and prevented decay at 4 °C and 25 °C. Ascorbic acid decreased the loss of moisture and the degradation of carbohydrates, vitamin C and lycopene at 4 °C and 25 °C. Salicylic acid decreased the degradation of protein at 25 °C. The low temperature was highly effective in decreasing the loss or degradation of most of the studied traits. Taken together, bio-stimulants and storing at 4 °C played a prominent role in extending the shelf life and preserving the quality of okra pods.
The Role of Methionine Supplementation on Oxidative Stress and Antioxidant Status of Poultry-A Review
Authors: Kachungwa Lugata James , Ortega Arth David Sol Valmoria , Szabó Csaba
Published: October 2022

The physiological status of poultry can be disturbed by different stressors that may lead to oxidative stress conditions. Oxidative stress activates defense systems, which mitigates the adverse effects. Several lines of the poultry defense system exist, including enzyme systems such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and non-enzymatic antioxidants such as Glutathione (GSH). Methionine—a vital amino acid in poultry nutrition—plays a significant role in protein synthesis, transsulfuration, and transmethylation and is also involved in several biochemical pathway activations that can affect the antioxidant system. Therefore, this review aims to summarize the current knowledge on the role of methionine in poultry under heat stress or managing stress, on the antioxidants responsible for scavenging free radicals (GSH) and those responsible for detoxification (SOD, CAT, and GPx). Different levels of methionine supplementation above the requirement (up to 1% Met added on the basal diet) have been tested on the antioxidant status of poultry. It has been shown to improve the antioxidant status and reduce oxidative stress. The results of many experiments on poultry supplemented with diets of different methionine sources indicate that L-Met has good potential to stimulate the antioxidant status of poultry.
Individual and Village Level Factors Affect Farmers’ Satisfaction with Sustainable Rural Development Practices: Evidence from Guangdong Province in China
Authors: Zhang Xiaojuan , Yang Zhengxi
Published: October 2022

Farmers are the most important stakeholders in the sustainable development of rural areas. Studying farmers’ satisfaction with sustainable rural development (SRD) practices can help us to understand how to mobilize farmers’ enthusiasm and initiative, such that they can play a major role in SRD. This study aimed to identify the factors influencing farmers’ satisfaction with SRD practices. Based on the survey data of 599 farmers in 57 villages in the Guangdong Province, Hierarchical Linear Modelling (HLM) was used to identify the influencing factors of farmers’ satisfaction with SRD practices in Guangdong Province at the individual and village levels. This study found that there was spatial heterogeneity in farmers’ satisfaction with SRD practices in the Guangdong Province, and factors at the individual level and village level jointly affected the farmers’ satisfaction. At the individual level, farmers’ college education, identity of Chinese Communist Party (CCP), and participation have positive predictive effects on farmers’ satisfaction. At the village level, the improvement of public services, village infrastructure, and grassroots governance has a positive predictive effect on farmers’ satisfaction. However, the improvement of the village living environment and the income of the village’s collective economy were not significant determinants of farmers’ satisfaction. The results provide practical implications for policymakers to guide farmers to actively participate in SRD practices.
Winter Wheat Yield Prediction Using an LSTM Model from MODIS LAI Products
Authors: Wang Jian , Si Haiping , Gao Zhao , Shi Lei
Published: October 2022

Yield estimation using remote sensing data is a research priority in modern agriculture. The rapid and accurate estimation of winter wheat yields over large areas is an important prerequisite for food security policy formulation and implementation. In most county-level yield estimation processes, multiple input data are used for yield prediction as much as possible, however, in some regions, data are more difficult to obtain, so we used the single-leaf area index (LAI) as input data for the model for yield prediction. In this study, the effects of different time steps as well as the LAI time series on the estimation results were analyzed for the properties of long short-term memory (LSTM), and multiple machine learning methods were compared with yield estimation models constructed by the LSTM networks. The results show that the accuracy of the yield estimation results using LSTM did not show an increasing trend with the increasing step size and data volume, while the yield estimation results of the LSTM were generally better than those of conventional machine learning methods, with the best R2 and RMSE results of 0.87 and 522.3 kg/ha, respectively, in the comparison between predicted and actual yields. Although the use of LAI as a single input factor may cause yield uncertainty in some extreme years, it is a reliable and promising method for improving the yield estimation, which has important implications for crop yield forecasting, agricultural disaster monitoring, food trade policy, and food security early warning.