bluuebunny/crossref_metadata_2025 huggingface dataset:
Exercise-Induced miR-210 Promotes Cardiomyocyte Proliferation and Survival and Mediates Exercise-Induced Cardiac Protection against Ischemia/Reperfusion Injury
Authors: Bei Yihua , Wang Hongyun , Liu Yang , Su Zhuhua , Li Xinpeng , Zhu Yujiao , Zhang Ziyi , Yin Mingming , Chen Chen , Li Lin , Wei Meng , Meng Xiangmin , Liang Xuchun , Huang Zhenzhen , Cao Richard Yang , Wang Lei , Li Guoping , Cretoiu Dragos , Xiao Junjie
Published: February 2024

Exercise can stimulate physiological cardiac growth and provide cardioprotection effect in ischemia/reperfusion (I/R) injury. MiR-210 is regulated in the adaptation process induced by exercise; however, its impact on exercise-induced physiological cardiac growth and its contribution to exercise-driven cardioprotection remain unclear. We investigated the role and mechanism of miR-210 in exercise-induced physiological cardiac growth and explored whether miR-210 contributes to exercise-induced protection in alleviating I/R injury. Here, we first observed that regular swimming exercise can markedly increase miR-210 levels in the heart and blood samples of rats and mice. Circulating miR-210 levels were also elevated after a programmed cardiac rehabilitation in patients that were diagnosed of coronary heart diseases. In 8-week swimming model in wild-type (WT) and miR-210 knockout (KO) rats, we demonstrated that miR-210 was not integral for exercise-induced cardiac hypertrophy but it did influence cardiomyocyte proliferative activity. In neonatal rat cardiomyocytes, miR-210 promoted cell proliferation and suppressed apoptosis while not altering cell size. Additionally, miR-210 promoted cardiomyocyte proliferation and survival in human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and AC16 cell line, indicating its functional roles in human cardiomyocytes. We further identified miR-210 target genes, cyclin-dependent kinase 10 (CDK10) and ephrin-A3 (EFNA3), that regulate cardiomyocyte proliferation and apoptosis. Finally, miR-210 KO and WT rats were subjected to swimming exercise followed by I/R injury. We demonstrated that miR-210 crucially contributed to exercise-driven cardioprotection against I/R injury. In summary, this study elucidates the role of miR-210, an exercise-responsive miRNA, in promoting the proliferative activity of cardiomyocytes during physiological cardiac growth. Furthermore, miR-210 plays an essential role in mediating the protective effects of exercise against cardiac I/R injury. Our findings suggest exercise as a potent nonpharmaceutical intervention for inducing miR-210, which can alleviate I/R injury and promote cardioprotection.
Masked Generative Light Field Prompting for Pixel-Level Structure Segmentations
Authors: Wang Mianzhao , Shi Fan , Cheng Xu , Chen Shengyong
Published: February 2024

Pixel-level structure segmentations have attracted considerable attention, playing a crucial role in autonomous driving within the metaverse and enhancing comprehension in light field-based machine vision. However, current light field modeling methods fail to integrate appearance and geometric structural information into a coherent semantic space, thereby limiting the capability of light field transmission for visual knowledge. In this paper, we propose a general light field modeling method for pixel-level structure segmentation, comprising a generative light field prompting encoder (LF-GPE) and a prompt-based masked light field pretraining (LF-PMP) network. Our LF-GPE, serving as a light field backbone, can extract both appearance and geometric structural cues simultaneously. It aligns these features into a unified visual space, facilitating semantic interaction. Meanwhile, our LF-PMP, during the pretraining phase, integrates a mixed light field and a multi-view light field reconstruction. It prioritizes considering the geometric structural properties of the light field, enabling the light field backbone to accumulate a wealth of prior knowledge. We evaluate our pretrained LF-GPE on two downstream tasks: light field salient object detection and semantic segmentation. Experimental results demonstrate that LF-GPE can effectively learn high-quality light field features and achieve highly competitive performance in pixel-level segmentation tasks.
Optical Coupling in Atomic Waveguide for Vertically Integrated Photonics
Authors: Wang Yue , Wang Junzhuan , Tian Ruijuan , Zheng Jiapeng , Shao Lei , Liu Bo , Wang Fengqiu , Gan Xuetao , Shi Yi , Wang Xiaomu
Published: February 2024

Integrated 2-dimensional (2D) photonic devices such as monolayer waveguide has generated exceptional interest because of their ultimate thinness. In particular, they potentially permit stereo photonic architecture through bond-free van der Waals integration. However, little is known about the coupling and controlling of the single-atom guided wave to its photonic environment, which governs the design and application of integrated system. Here, we report the optical coupling of atomically guided waves to other photonic modes. We directly probe the mode beating between evanescent waves in a monolayer 2D waveguide and a silicon photonic waveguide, which constitutes a vertically integrated interferometer. The mode-coupling measures the dispersion relation of the guided wave inside the atomic waveguide and unveils it strongly modifies matter’s electronic states, manifesting by the formation of a propagating polariton. We also demonstrated light modulating and spectral detecting in this compact nonplanar interferometer. These findings provide a generalizable and versatile platform toward monolithic 3-dimensional integrated photonics.
Personal names and power: Binary personal naming system of the Baatombu people in Nigeria and Republic of Benin
Authors: Williams Azibaoguanasi
Published: February 2024

The paper explores the unique personal naming system of the Baatombu people. The Baatombu, an indigenous group located in Nigeria and Republic of Benin, have developed a binary naming system that categorizes names into two distinct categories, A or B. This paper aims to understand the cultural and social significance of this naming system within the Baatombu community. Through an in-depth analysis of interviews and field observations, the author uncovers the underlying principles and factors that determine whether a name falls under category A or B. The paper also examines the implications and symbolism embedded in these binary categories and how they contribute to the cultural identity and social structure of the Baatombu people. This study sheds light on the intricate relationship between personal names, cultural practices, and social dynamics, offering insights into the Baatombu’s unique perspective on personal identity and community cohesion.
Toponymic approach to the geographical research of cultural heritage: The cases of three Moldavian places
Authors: Herzen Andrey , Herzen Olga
Published: February 2024

Place names playing a significant role in the life of human communities throughout history have been formed in historical-geographical landscapes under the influence of various natural and cultural factors in specific linguistic and ethnic environments. Over the centuries of landscape and human evolution as well as by changes in human perception of space, contradictions and even conflicts between and on toponyms arose. This makes toponymic research permanently topical. The combined use of geographical, linguistic and historical methods increases the efficiency of toponymic research and makes the conclusions more meaningful and profound. It also encourages interdisciplinary integration and knowledge consolidation from different areas of science for the sake of getting closer to the truth. This article presents a toponymic approach to geographical research of the cultural heritage by means of a historical-cartographic analysis of places in the northwestern Black Sea region. The three cases represent different types of places: Kishinev [Chişinău], Bender and Rashkov [Raşcov].
FINANCIAL DISTRESS AND OTHER FINANCIAL CONDITIONS ON GOING CONCERN AUDIT OPINIONS
Authors: Salim Agus
Published: February 2024

This study aims to examine the effect of Financial Distress, Leverage, Solvency, Profitability and Liquidity on Going Concern Audit Opinions. This research uses company data listed on the IDX and consistently enters the group of manufacturing companies from 2019-2021. This study uses a logistic regression analysis tool using SPSS to answer the proposed hypothesis. The results showed that Financial distress had an effect on going-concern audit opinion, Leverage had no effect on going-concern audit opinion, Solvability had no effect on going-concern audit opinion, Profitability had no effect on going-concern audit opinion, Liquidity had no effect on going-concern audit opinion
UNRAVELING GORONTALO'S LOCAL WISDOM: THE ESSENCE OF COST ACCOUNTING PRACTICE
Authors: Thalib Mohamad Anwar
Published: February 2024

This research departs from the problem of adopting and implementing modern accounting, which can potentially eliminate local wisdom values from accounting practices. This study aims to find the values of local wisdom behind the practice of education cost accounting by scholarship recipient students. This research uses the Islamic paradigm. The approach used is Islamic ethnomethodology. There are five data analysis stages: charity, knowledge, faith, revelation information, and courtesy. The study results found that students used funds from the government to finance educational needs for one semester. Funds sourced from parents are used by students, one of which is to give alms and help to human beings. The practice of accounting in managing educational expenses is conditional on local wisdom values in the form of trust (ama:nati) and mutual help (huyula). Both of these spirits live on the belief that there are other people's rights behind the sustenance that we have and Allah has arranged the sustenance. The results of this study contribute to the presence of the concept of cost accounting practices by students based on local cultural values
EXPLORING FACTORS THAT SHAPE INDONESIAN’S INTENTIONS TO PURCHASE HERBAL MEDICINE
Authors: Keni Keni , Wilson Nicholas , Dharmawan Purnama
Published: February 2024

The pharmaceutical industry has emerged as one of the most rapidly expanding sectors globally, and this trend holds true for Indonesia as well. Within this industry, a notably popular type of medication in Indonesia is herbal medicine. This variant of medicine is derived from traditional and natural ingredients, with minimal incorporation of chemical substances. To delve into this phenomenon, the present study aims to identify the factors influencing Indonesians' inclination and intention to purchase herbal medicine. To achieve this, the study integrates key variables from the original Theory of Reasoned Action (TRA) framework, namely attitude and subjective norm, along with an additional element – perceived value. The methodology employed involves a survey-based approach, utilizing questionnaires as the primary data collection tool among the chosen participants. The sampling method chosen is non-probability purposive sampling, ensuring that only individuals who meet the predetermined criteria participate – specifically, individuals who have acquired herbal medicines within the past 6 months. Employing a 7-point Likert scale, a total of 156 data points were amassed. The analysis was conducted using Partial Least Squares Structural Equation Modeling (PLS-SEM), with SmartPLS 4 software being the designated tool. Through the scrutiny of the data, the authors conclude that attitude, subjective norm, and perceived value significantly impact consumers' intention to purchase herbal medicine in Indonesia.
Studying the spectrometric features of forest seeds to improve sowing qualities: a retrospective cluster analysis of the scientific landscape trends
Authors: Novikova Tatyana , Novikov Arthur , Petrishchev E.
Published: February 2024

Forest seeds spectral data in the visible and infrared regions of electromagnetic radiation lengths quite effectively
differentiate the origin, viability, types of seeds, their infestation with pests and diseases, the ability to absorb and lose
water. The search for a method of seed testing that is both experimentally simple, fast and effective for predicting germination is necessary to increase the energy efficiency of forest nurseries in the production of planting material. The retrospective references systematization (N = 55, 1998-2023, terms [Scholar Query = seeds* AND (spectr* OR optic*) (properties OR features) AND analysis]) into clusters was carried out on the basis of eight performance criteria represented by
rank variables. The level of similarity and difference between clusters is determined by the method of the most distant
neighbors with the grouping of data by the square of the Euclidean distance. The most distant criterion from other criteria
is the level of invasiveness of testing (the square of the Euclidean distance is 25, p < 0.05). Correlation analysis of nonparametric criteria indicates a direct strong interaction between the level of financial and organizational costs (Spearman
coefficient ρ = 0.77; p = 0.0008), time costs and low machine learning capability (ρ = 0.725; p = 0.0008). In the future, it
is planned to periodically supplement the set of systematic data to obtain an objective assessment of seed testing methods,
as well as using a seed passport to evaluate the relationship of RGB spectral data of more than 1 000 individual seeds
with early growth of seedlings in a post-pyrogenic experimental site of the forest landscape of the Voronezh region by
example (Pinus sylvestris L. var. Negorelskaya).
FLR-Library reference information system for adaptive forest restoration: the information model
Authors: Novikova Tatyana , Novikov Arthur , Lisitsyn Viktor , Petrishchev E.
Published: February 2024

The process of restoring forest landscapes in the context of global urbanization and deforestation of relict stands,
as well as climate change, is complex and important for studying, planning stages and technological operations and
predicting the results of vitality and growth of stands. To solve this problem, a reference information system for adaptive
reforestation is being developed. In this paper, the modeling and description of the adaptive reforestation process is carried
out using functional diagrams constructed using the IDEF0 methodology, and the description of the arrows of the context
diagram with explanations of the processes is given in detail. For a detailed analysis of the subject area and modeling of
the adaptive reforestation process, we decomposed the context diagram into diagram A1, which shows the implementation
of the process of choosing a technology for the restoration of the forest landscape from the point of view of technology
and technical means, and diagram A2, which examines the restoration technology from the point of view of several
forestry descriptors, which takes into account the specifics of the industry. As a result of the simulation, diagrams A0,
A1, A2 were obtained, which show a structured image of the system functions, information and objects connecting these
functions.
Enerji Depolama ile Elektrik Dağıtım Şebekesinin İşletme Maliyeti Optimizasyonu
Authors: Avli Fırış Fatma , Karadöl İsrafil , Keçecioğlu Ö. Fatih
Published: February 2024

Bu çalışmanın amacı, yenilenebilir ve dağıtık enerji kaynaklarının bulunduğu elektrik dağıtım şebekesinin fider ölçeğinde enerji depolama sistemi kullanılarak minimum işletme maliyeti sağlamaktır. Şebekenin işletim optimizasyonu, çalışmada geliştirilen iki aşamalı stokastik programlama problemi ile ele alınmıştır. Problem, General Algebraic Modelling System (GAMS) aracılığıyla doğrusal bir model olan Mixed Integer Linear Programming (MILP) ile formüle edilmiş ve CPLEX çözücüsü ile çözülmüştür. Modellemedeki belirsizliklerin ele alınabilmesi için Monte Carlo Simülasyonu aracılığıyla senaryo üretimi ve azaltımı gerçekleştirilmiştir. Önerilen modelin etkinliğini doğrulamak için gerçekleştirilen simülasyon çalışmaları, IEEE-33 test baraları üzerinde uygulanmıştır. İşletme maliyetleri olası şebeke koşulları altında hesaplanmış ve kendi aralarında enerji depolamanın kullanımlarına göre karşılaştırılmıştır. Edinilen sonuçlara göre, şebekeye enerji depolama sistemi entegre edildiği durumlarda, depolama sisteminin hiç bulunmadığı durumlara göre işletme maliyetinde yalnıca bir günlük ortalama zaman periyodunda 200 doları aşkın bir düşüş gözlenmiştir. Böylece önerilen sistemle birlikte enerji depolamanın optimum şekilde programlanmasının; işletme maliyetlerini düşürmede ve dolayısıyla güç sistemlerinin en kritik konularından biri olan ekonomik optimizasyonun sağlanmasında etkin bir yöntem olduğu doğrulanmıştır.
Baseline Indicator for Program Evaluation: Case Study of Millennial Farmer Program in West Java Province
Authors: Kurniawan Dicky Eka , Ningrum Sinta , Widianingsih Ida
Published: February 2024

The design of a policy or program evaluation study is both descriptive and analytical. On the one hand, evaluators try to describe what has happened, and on the other hand, try to explain why it happened. To do this, evaluators need to observe what happens before and after the policy or program is implemented. This research aims to describe phenomena related to the agricultural sector in West Java Province before the millennial farmer program was implemented in 2021. Such knowledge will be useful as baseline indicator when assessing the program's performance and impact. This research uses a qualitative approach with a case study design and a literature study review. The data source used is secondary data in the form of previous study and statistical data obtained from the Central Bureau of Statistics (BPS). The results showed that there were six empirical phenomena that described the condition of the West Java agricultural sector before the millennial farmer program was implemented, namely the percentage of young farmers that continued to decline, the low average wage of agricultural workers, the deficit exchange rate of farmers (NTP), the structure of the agricultural sector workforce that shifted towards non-agriculture, the contribution of the agricultural sector to GRDP that decreased, and the position of agriculture as a lagging business sector according to the results of Klassen analysis. These six phenomena can be used as baseline indicators to assess program performance and impact in the next five or ten years.
The Innovation Capacity of the Electronic Traffic Law Enforcement (ETLE) of the Indonesian National Police Viewed by the Observatory of Public Sector Innovation (OPSI) Framework
Authors: Narendroputro Wiryawan , Rusfian Effy Zalfiana
Published: February 2024

Electronic Traffic Law Enforcement (ETLE) has been inaugurated and is expected to improve the image of the National Police, minimize extortion practices by officers, and increase driving discipline. Apart from that, ETLE is a National Police program to realize good governance with the values of transparency, accountability and responsiveness. This paper aims to analyze problems in the ETLE program using the Observatory of Public Sector Innovation (OPSI) Innovation Framework prepared by the Organization for Economic Co-operation and Development (OECD). The OPSI Framework consists of innovation objectives, potential, capacity, and impact. The analysis uses the OPSI Innovation Framework to identify problems that occur in innovation to carry out improvements and developments to create sustainable innovation. Based on the results of research using the OPSI framework, ETLE has several problems: requiring a lot of infrastructure with significant resources, an organizational culture that is still silo-like, community disobedience to rules and an organizational culture that is still traditional. The solution to this problem is: First, for limited infrastructure that requires a large budget, apart from collaborating with regional governments, the National Police can also request support from the central government to provide infrastructure for the implementation of ETLE throughout Indonesia because this is a priority program for the National Police; Second, the rules were not followed openly, the police had to carry out intensive information activities about ETLE and issue manual fines to deal with violations on the spot. Third, regarding organizational culture, the Police Chief, as the leader of the National Police, can create an innovative and agile corporate culture and implement collaborative governance with various stakeholders.
Implementation of Public Service Malls (MPP) in Improving One Stop Integrated Services (PTSP) in Rembang Regency
Authors: Riski Dwi Yoga Ambal , Yuningsih Tri , Herawati Augustin Rina
Published: February 2024

Public services in Indonesia are often seen as a complicated and long-winded process, so people need public services that are easier to reach. The Rembang Regency Public Service Mall exists as an effort by the Rembang Regency Government to improve the quality of integrated services. This study aims to determine how Public Service Malls's implementation, factors, and SWOT analysis (PSM) improved One Stop Services in Rembang Regency. This research method descriptively uses qualitative data sources obtained through in-depth interviews. The results of the study showed that (1) The effectiveness of the Public Service Mall in improving One-Stop Services in Rembang Regency is still considered ineffective; (2) The implementation of the PSM policy in Rembang Regency in terms of resources and bureaucratic structure is not optimal; (3) Strategies that the Government of Rembang Regency can develop in the implementation of this PSM policy include preparation of standard operating procedures for macro service mechanisms at PSM, development of information systems for Public Service Malls, and improvement of PSM service facilities
The Social Underpinnings of Language Practices in Swedish-English Families
Authors: Roberts Tim
Published: February 2024

By means of a large-scale quantitative approach, this study examines the declared family language practices of Swedish-English bilingual families living in Sweden, and how an array of family-external and family-internal social factors correlate with divergences in these practices. For the purpose of this study, a Swedish-English bilingual family consists of two parents, one of which is an L1 English speaker, and the other is an L1 Swedish speaker, as well as their children. The data comes from a digital questionnaire completed by 438 families, which was analysed using non-parametric statistics. The results show that despite a preference for English amongst the parents in these families, their children are more likely to use Swedish in sibling interaction, which can be regarded as an indication of the influence of wider society on home language practices. The results also show that a number of social factors correlated with a divergence in declared language practices in these families, namely, parental occupation, the migratory history of the family, parent’s marital status, family involvement in parent-child English speaking groups, and whether the mother or the father was the L1 English speaker. Other typically cited social factors, such as parental education level, showed no significant correlation with declared language practices in these families. The study comments on raising bilingual children in a context where both languages are valued in society, and the implications for this internationally. The study also exemplifies the complex, context sensitive situation that is encountered when attempting to fully understand family language policies more generally.
Käthe Kruse babakészítő sajtóreprezentációja a 20. század elején Magyarországon
Authors: Pásztor Enikő
Published: February 2024

Käthe Kruse, a világ talán egyik legismertebb babakészítője, a reformbabák megálmodója, élete egy rövid szakaszát Monte Veritàn, egy kommunában töltötte. Művészi fejlődésének kezdete is ehhez a helyhez köthető. Bár az asszonyt kifejezetten taszították az ottani ideológiák, erősen hatott rá a lakók vonzódása a természethez. A Das grosse Puppenspiel című önéletrajzi könyve amellett, hogy betekintést enged a babakészítő életének főbb állomásaiba, alkotói tevékenységébe, további információval szolgál az életreform-mozgalmak, ezeken belül is a Henry Ödenkoven által alapított Monte Verità-i kommuna megismeréséhez. Ennek azért van jelentősége, mert bár Käthe Kruse nem tudott teljesen azonosulni a Monte Verità-n élt kommuna lakóinak szellemiségével, és nem tudott teljes mértékig bekapcsolódni a reformmozgalomba, mégis erre a helyre és életének erre a szakaszára mint művészi kiteljesedésének bölcsőjére tekinthetünk. Jelen írásomban azt a tartalomelemzésre épülő primer kutatásomat helyezem fókuszba, melyben arra kerestem a választ, vajon Käthe Kruse munkássága a 20. század első két évtizedében hogyan reprezentálódik a korabeli magyar napi- és hetilapokban, folyóiratokban.
A család a nevelésszociológia szemszögéből, a fogyatékosság és az integráció kontextusában
Authors: Giczi Barnabásné Fehér Ágnes
Published: February 2024

A család mint a szocializáció és nevelés elsődleges színtere a nevelésszociológia kiemelt vizsgálati körébe tartozik. A család, mint társadalmi intézmény, csoport és rendszer, kulcsfontosságú szerepet játszik az egyén életében, különösen a sérüléssel élők esetében, akik még inkább támaszkodnak annak különböző funkcióira az anyagi, érzelmi és társadalmi erőforrásaik mobilizálása során. Bár ezek a családok minden társadalmi rétegben megtalálhatók, gyakran tapasztalható, hogy a kiváló képességek ellenére sem érik el a magasabb foglalkoztatási státuszt a tanulási és elhelyezkedési lehetőségeik korlátozottsága miatt. A sikeres együttneveléshez – amely hozzájárulhat az érintett személy életszínvonalának javulásához – objektív tényezők, mint a megfelelő infrastruktúra, illetve szubjektív tényezők, beleértve a pedagógusok és a családok együttműködését, egyaránt elengedhetetlenek. A család aktív részvétele, bevonódása, attitűdje kulcsfontosságú mind az együttnevelés, mind a gyermek intézményes nevelésének és oktatásának eredményessége szempontjából.
A játék és a tanulási motiváció összefüggése a tanulásban akadályozottak oktatási-nevelési folyamatának aspektusából
Authors: Mendéné Lajtai Krisztina
Published: February 2024

Társadalmi elvárás az iskolai oktatással szemben, hogy a diákokat a munkára, a mindennapi élethelyzetek adta problémák megoldására készítse fel. Ennek kívánalma, hogy a diákok, rendszerezett, transzformálható tudással lépjenek ki az iskola kapuján. A jelen kor oktatásában óriási kihívás a pedagógusok számára, hogy a tanítási-tanulási folyamat aktív részeseivé váljanak a tanulók. Nem kis feladatot jelent ez a tanulási nehézséggel küzdő gyermekek megfelelő tanulási motiváltságának kialakítása tekintetében, melyek a tanulás sikerességéhez, alapvető kompetenciák elsajátításához vezetnek el. A téma aktualitását azon módszertani tendenciák előtérbe kerülése adja, melyek hangsúlyt fektetnek a játékalapú tevékenységen keresztül az élményszerű felfedezést nyújtó ismeretelsajátításra. Ezen gyakorlatok fókuszában a tanulók sokoldalú képesség- és személyiségfejlesztése áll, melyek jól illeszthetők a tanítási órák rendszerébe. Jelen tanulmányomban a tanulásban akadályozottak oktatási-nevelési folyamatában a játék és a tanulási motiváció összefüggését vizsgálom meg.
PENERAPAN PENDIDIKAN KARAKTER DALAM MENINGKATKAN KEBIASAAN IBADAH SHALAT PESERTA DIDIK DI SDIT AL ISTIQOMAH DAN MIS AL-‘IANAH KABUPATEN KARAWANG
Authors: Iskandar Sofyan , Nurlaeli Acep
Published: February 2024

Karakter bisa diartikan bagaimana mengaplikasikan atau mengukir nilai kebaikan dalam bentuk tindakan atau tingkah laku, sehingga orang yang tidak jujur, kejam, rakus, dan berperilaku jelek dikatakan orang berkarakter jelek. Sebaliknya, orang yang perilakunya sesuai dengan kaidah moral disebut orang berkarakter mulia. Dalam menumbuhkan pendidikan karakter, perlu adanya kesadaran dari berbagai pihak untuk memulai dan menjadi pembiasaan. Pendidikan berperan kuat dalam pembentukan karakter peserta didik. Penelitian mengenai penerapan pendidikan karakter dalam meningkatkan ibadah shalat. Ini difokuskan pada nilai-nilai pendidikan karakter dalam meningkatkan ibadah shalat. Masalah yang dikaji dalam penelitian ini adalah nilai-nilai pendidikan karakter dalam meningkatkan ibadah shalat peserta didik di SDIT Al–Istiqomah dan MI Al–I‟anah Kabupaten Karawang. Berkaitan dengan masalah tersebut penelitian ini bertujuan untuk mengungkap nilai-nilai pendidikan karakter yang dikembangkan pada nilai – nilai pendidikan karakter dalam meningkatkan ibadah shalat. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif deskriptif. Data penelitian ini adalah penerapan pendidikan karakter dalam meningkatkan ibadah shalat. Sumber data dalam penelitian ini adalah SDIT Al-Istiqomah dan MI Al-I‟anah. Proses pengumpulan data menggunakan metode observasi, wawancara dan dokumentasi. Setelah data
Peran Pendidikan Islam dalam Membangun Peradaban Islam di Indonesia
Authors: Nur Laila Imailda
Published: February 2024

Pendidikan memiliki pengaruh yang besar dalam membangun peradaban Islam. Sejak masa perkembangan Islam, pendidikan telah mendapatkan prioritas utama bagi masyarakat muslim di Indonesia. Pendidikan Islam merupakan pendidikan yang ideal, pendidikan Islam tumbuh dan berkembang sejalan dengan dakwah Islam yang diemban oleh Nabi Muhammad SAW. Tujuan penelitian ini adalah untuk memberikan informasi kepada pembaca tentang pentingnya peran pendidikan Islam dalam membangun peradaban Islam di Indonesia. Metodologi penelitian meliputi studi kepustakaan atau literatur review, dimana pengkajian dilakukan secara objektif dan sumber datanya adalah buku-buku literatur, maupun jurnal penelitian yang berkaitan dengan topik atau variabel penelitian. Hasil dari penelitian ini adalah untuk menyampaikan pengetahuan bahwa pendidikan Islam adalah pendidikan yang bertujuan untuk membentuk kepribadian muslim seutuhnya dengan mengembangkan setiap potensi yang ada, baik potensi jasmani maupun rohani, serta dapat mendorong hubungan yang harmonis antara Allah SWT, manusia dan alam semesta.
COMPARISON OF ANGLE OPENING DISTANCE AND TRABECULAR IRIS SPACE AREA BEFORE AND AFTER LASER PERIPHERAL IRIDOTOMY IN ANGLE CLOSURE DISEASE
Authors: Ramdhani Rizki Fasa , Rifada R. Maula , Irfani Irawati , Gustianty Elsa , Umbara Sonie
Published: February 2024

Introduction & ObjectivesLaser peripheral iridotomy (LPI) is the standard first-line therapy in angle closure disease toincrease anterior chamber angle width. Spectral Domain Anterior Segment Optical CoherenceTomography (SD AS-OCT) is an instrument that has a quantitative parameter to measure anteriorchamber angle. Angle opening distance (AOD) and trabecular iris space area (TISA) are quantitativeparameters in SD AS-OCT. The purpose of this study is to compare AOD and TISA before and oneweek after LPI in angle closure disease.

MethodsThis is an analytical prospective study with a cross-sectional study design. Twenty-two eyes withangle closure disease that met inclusion and exclusion criteria underwent LPI and SD AS-OCT beforeand one week after LPI. Analysis was performed using SD AS-OCT parameters, such as AOD(AOD500, AOD750) and TISA (TISA500, TISA750) in the temporal, nasal quadrants, and average.

ResultsTwenty-two eyes with angle closure are divided into nine eyes with primary angle closure suspect,seven eyes with primary angle closure, and six eyes with primary angle closure glaucoma. The meanage of participants was 57.86±7.63 years. There was a significant increase in AOD500, AOD750,TISA500, and TISA750 in the temporal and nasal quadrants, as well as in the average (P=0.0001)based on a paired t test or Wilcoxon as an alternative. Average AOD750 had the highest T-value (T=6.329) with a mean 0.20±0.096 before LPI and 0.31±0.144 one week after LPI.

ConclusionThere was a significant increase in AOD and TISA after one week LPI in angle closure disease.
Treatment of Vitreous Hemorrhage due to Proliferative Diabetic Retinopathy in Cipto Mangunkusumo Hospital During Pandemic Era (March 2020 - March 2022)
Authors: RAHAYU TSANIA RACHMAH , Andayani Gitalisa
Published: February 2024

Introduction & ObjectivesProliferative diabetic retinopathy (PDR) is the most common etiology for vitreous hemorrhage (VH)and can be sight-threatening. Current treatment modalities for VH in PDR included anti-VEGFinjection, panretinal photocoagulation (PRP) laser, and vitrectomy. We conducted study to evaluatetreatment modalities and outcomes of VH in PDR during the pandemic era.

MethodsA retrospective study of VH in PDR was conducted at Cipto Mangunkusumo Hospital, Indonesia,from March 2020 to March 2022. Primary treatment was the therapy planned at the initial visit,while secondary treatment was subsequent treatment after follow-ups. Good anatomical outcomewas defined as vitreous clearing at last follow-up, while functional outcome was visual acuity (VA)improvement in LogMAR.

ResultsThis study included 83 patients (97 eyes), which is smaller than the previous study in our centerbefore the pandemic. Mean age was 54,28±8,57 years, with almost equal males and females. InitialVA was LogMAR 2,48 (0,15 – 2,80). The most frequent treatment for VH in PDR was vitrectomy(53,5%), followed by anti-VEGF injection, PRP laser, and observation. Glaucoma after vitrectomy wasthe most common complication (5,2%). Vitreous clearing was achieved in 85,5% of cases, which wassignificantly associated with vitrectomy surgery (p=0,013) and initial treatment time (p=0,023). TheVA improvement was LogMAR -0,48(-2,48–2,40) which was related to initial VA (p<0.05), yet therewas no significant association with treatment modality.

ConclusionVitrectomy is essential to achieve vitreous clearing in VH caused by PDR. Initial visual acuity, notthe type of treatment modality, is a significant factor in vision improvement.
The Correlation between Retinal Nerve Fibre Layer Thickness, Optic Nerve Head Parameter, and Related Risk Factor in Glaucoma Patient
Authors: Wardhana Arif Kusuma , Ekantini Retno , Gani Tatang Talka , Jati Krisna Dwi Purnomo
Published: February 2024

Introduction & ObjectivesTo investigate the correlation between retinal nerve fibre layer (RNFL) thickness and the past RNFLthickness, related risk factor (gender, age, myopia, intraocular pressure (IOP), blood pressure). AndRNFL parameter (symmetricity and four quadrants RNFL thickness) and optic nerve head parameter(rim area and vertical cup disc ratio)

Methods39 right eyes of both sex and various age underwent examination including IOP measurement,subjective refraction for determining refractive error, and optical coherence tomography (OCT) forRNFL and ONH analysis. The follow up were done after one year.

ResultsThe RNFL symmetricity, superior, nasal, inferior, temporal RNFL thickness showed significancecorrelation with RNFL thickness (R= 0.487, p= 0.002), (R= 0.915, R= 0.749, R= 0.897, R= 0.702with p= <0.001), but not showed significance correlation with rim area and vertical cup disc ratio(R= 0.175, p= 0.286) and (R= -0.093, p= 0.574). A significance correlation also showed withincreasing age, gender, and systolic blood pressure (R= -0.387, p= 0.015), (R= 0.441, p= 0.005) and(R= -0.418, p= 0.008). But not showed significance correlation with history of past RNFL thickness,refractive error, IOP, and diastolic blood pressure (R= 0.258, p= 0.113), (R= 0.005, p= 0.975), (R=-0.234, p=0.152), and (R= 0.060, p=0.717).

ConclusionRNFL thickness measurements showed significance correlation with RNFL parameter. It is not clearif past RNFL thickness, refractive error and IOP related with RNFL thickness even showedsignificance correlation with age, gender, and systolic blood pressure.
Outlook of Diabetic Retinopathy Management through Universal Health Care in Indonesia from 2015 – 2020
Authors: Zaharo Alfia Fatma , Wardhana Firman Setya , Supanji  , Sasongko Muhammad Bayu
Published: February 2024

Introduction & ObjectivesTo identify the National Health Expenditure associated with diabetic retinopathy (DR) from theperspective of Jaminan Kesehatan Nasional [JKN].

MethodsA dataset of 1% of all individuals registered in JKN database was used from 2015 to 2020. Weretrieved primary diagnosis with type 2 diabetes mellitus (T2DM) (ICD-10 E11) and/or T2DM withophthalmic complications (E11.3). Further diagnosis with DR (H36) was retrieved. Four groups ofmedical procedures related to DR management were developed according to Indonesian Case BaseGroups (INA-CBGs): diagnostic, laser photocoagulation and cryotherapy, minor (intravitrealinjection), and major surgical procedures (e.g., vitrectomy). We performed descriptive analyses forthe annual costs incurred for procedures, premium classifications, and regions.

ResultsOverall DR costs were US $41.5 million from 156,752 individuals with DR in JKN database sample.The total cost and per unit procedures cost specifically increased annually from 2015 to 2019 butdeclined substantially in 2020. The largest amount was spent on intravitreal injection ($36.3 million[87.5%]), whereas vitrectomy was the least ($145.0 million [0.3%]). Region 1 (Java Island) with nonbeneficiariesof government subsidies (PBPU and PPU) was the major number of claims ($12.5million [30.1%] and ($7.3 million [17.7%]), while beneficiaries of government subsidies (PBI) outsideJava Island, conversely, were under average.

ConclusionThere was significant increase in health expenditure associated with DR in Indonesia from 2015 to2019, but decreased in 2020 possibly due to COVID-19 pandemic. Majority of funding was spent totreat severe spectrum of DR and concerned in urban area.
Comparation of Bevacizumab Intravitreal Injection Effects with and without Yellow Subthreshold Micropulse Laser (577-nm) Combination on Central Macular Thickness and Best Corrected Visual Acuity of Mild-Moderate Diabetic Macular Edema Patients
Authors: UTAMI ALIA NESSA , Djatikusumo Ari , Khoe Levina Chandra
Published: February 2024

Introduction & ObjectivesThe management of macular edema is constantly evaluated, with anti-VEGF therapy being the firstline. Subthreshold micropulse laser (SML) has been proposed as alternative adjuvant. Previousretrospective studies demonstrated the effectiveness of 577-nm SML as monotherapy in macularedema with CMT below 400 ?m. However, prospective data on the effectiveness of SML as adjuvantis lacking. The aim is to assess the effect of the combination of bevacizumab and 577-nm SML lasercompared to bevacizumab monotherapy on central macular thickness and visual acuity in mildmoderatediabetic macular edema patients.

MethodsA prospective randomized clinical trial was performed on diabetic macular edema patients withmacular thickness range of 300-600 ?m. Subjects are divided into two groups. The control groupreceived a standard protocol and the study group received a yellow SML laser adjuvant one weekafter injection. Patients underwent follow-up assessment of visual acuity and central macularthickness at 28 and 35 days post-injection.

Results26 subjects were equally divided into study and control groups. Significant decrease in CMT werefound in study group (p=0.011 and 0.014) and the control group (p=0.006 and p=0.001). However,there was no significant difference in ?CMT values between the two groups in the 28-day (p=0.317)and 35-day controls (p=0.84). There was no difference in ?BCVA ETDRS between the study andcontrol groups at 28 days (p=0.568) and 35 days (p=0.128) after injection.

ConclusionThe combination of SML and intravitreal bevacizumab can reduce central macular thickness andimprove visual acuity but there was no significant difference with standard monotherapy.
THE ASSOCIATION BETWEEN ATRIAL FIBRILLATION AND CENTRAL RETINAL ARTERY OCCLUSION: A META-ANALYSIS AND SYSTEMATIC REVIEW
Authors: Amelia Yufilia Suci , Alberta Ivana Beatrice , Angelia Maria , Pratama Kevin Gracia
Published: February 2024

Introduction

Central retinal artery occlusion (CRAO) is a condition where the central retinal artery is blocked. Atrial Fibrillation (AF) is commonly associated with retinal embolism that originates anywhere between the heart and the ophthalmic artery. This study aims to explore the incidence of AF in CRAO.

Methods

A systematic search was performed in three databases: Pubmed, EBSCO host, and Proquest. Newcastle-Ottawa Scale was used to assess the risk of bias in the study included.

Results

Our systematic review comprises six studies, 4 studies included CRAO patients as the study population and AF as the endpoint, and the other 2 studies with CRAO as the endpoint. Meta-analysis of the first group resulted in a significantly favorable AF incident after CRAO with an odds ratio (OR) of 1.46 (95% CI 1.17-1.81, p=0.0007). The second metaanalysis supports CRAO with an OR of 4.86 (95% CI 2.30-10.28, p<0.0001).

Discussion

Our study indicates that AF is a significant risk factor for CRAO. Extended cardiac monitoring may play a crucial diagnostic role in CRAO patients, and longer-term monitoring (23 years) may be a reasonable option as part of the diagnostic workup. Short-term monitoring alone may fail to detect a significant proportion of patients with underlying AF.

Conclusions

It is crucial to identify AF in preventing ocular infarction. This study revealed that AF was identified as a risk factor in patients with CRAO and vice versa.
A systematic review comparing Mytomicyn-C subtenon injection to sponge during trabeculectomy in open angle glaucoma
Authors: Ethelind Rachel , Puspa Prizka Avilia , Santoso Wildan Iman
Published: February 2024

Introduction & ObjectivesMitomycin-C (MMC) is an effective agent to prevent scarring during the healing process followingtrabeculectomy procedure by inhibiting the multiplication of cells producing scar tissue. The aim ofthis study is to compare the efficacy of Mitomycin-C (MMC) delivered by either subtenon injection orsponge application during trabeculectomy surgery in open angle glaucoma patients.

MethodsA systematic search was done using several databases including Pubmed, Medline, Embase, Scopus,and Jstor. Inclusion criteria were open angle glaucoma patients underwent trabeculectomy surgery,given either MMC via subtenon or sponge application, article in English, Randomized ControlledTrial (RCT) studies which published in the last 10 years. Intra-Ocular Pressure (IOP), EndothelialCell Counts (ECC) and Bleb Morphologic features with at least 1 month follow-up were evaluated.

ResultsTwo RCT studies were included in this study. Both studies demonstrated that sub-tenon injectionand sponge application has no significant difference regarding IOP reduction from the baseline.Regarding morphologic features, both studies favor subtenon to conventional sponge application.Lastly, ECC in both studies conclude that there was no marked differences.

ConclusionThe outcome of administration of MMC through subtenon injection and sponge application werecomparable to one another. However, less vascularization are shown in subtenon injection group.
Automation of the technological processes of wastewater treatment: case study of the Minsk wastewater treatment plant of UE Minskvodokanal
Authors: Иванович В.В. , Гуранчик А.Г. , Дубовик О.С. , Ануфриев В.Н.
Published: February 2024

Приведен опыт УП «Минскводоканал» по разработке и организации автоматизированных систем управления технологическим процессом очистки сточных вод на примере нескольких сооружений Минской очистной станции. Описаны цели и задачи, которые выполняются АСУ ТП на станции. Представлены структура и режимы работы реализованных систем. Детально рассмотрены этапы процесса очистки сточных вод: процеживание на решетках, удаление и обработка песка, подача и распределение воздуха по секциям аэротенков. В рамках автоматизации представленных стадий очистки описано общее построение АСУ ТП, приведены особенности эксплуатации, используемые объекты и режимы автоматизации. Особое внимание уделено необходимости простых и надежных алгоритмов управления. Конечной целью модернизации АСУ ТП Минской очистной станции является максимальная степень автоматизации и диспетчеризации, охватывающие всю технологическую цепочку очистки сточных вод и обработки осадка и основанные на простых и надежных принципах.

The experience of UE Minskvodokanal in developing and establishing of automated control systems for the technological process of wastewater treatment is presented using the example of several structures of the Minsk wastewater treatment plant. The goals and tasks performed by the automated process control systems at the plant are described. The structure and operating modes of the implemented systems are presented. The stages of the wastewater treatment process are considered in detail: screening, sand removing and processing, supplying and distributing air across sections of the aeration tanks. As part of the automation of the presented treatment stages, the general design of the automated process control system is described, the operating features, the objects used and automation modes are given. Special attention is paid to the need for simple and reliable control algorithms. The ultimate goal of upgrading the automated process control system of the Minsk wastewater treatment plant is the maximum degree of automation and supervisory control covering the entire technological chain of wastewater and sludge treatment based on the simple and reliable principles.
Aspects of designing wastewater treatment facilities in terms of the BAT process indicators: priorities and consequences
Authors: Самбурский Г.А. , Погорелый А.М. , Леонтьева С.В. , Никитина С.В.
Published: February 2024

Переход на концепцию технологического нормирования происходит одновременно с реализацией ряда федеральных проектов экологической направленности, в том числе входящих в национальный проект «Экология». Учитывая то, что водоканалы с позиций Росприроднадзора являются одними из основных загрязнителей водных объектов, строительство новых и модернизация действующих очистных сооружений находится в фокусе органов власти, контролирующих органов и, естественно, самих организаций, которые занимаются эксплуатацией очистных сооружений канализации. В статье рассмотрены потенциальные и возможные несоответствия текущих ожиданий по поводу проектирования, исходя из технологических показателей наилучших доступных технологий и самой концепции использования наилучших доступных технологий, которая подразумевает не статичность, а развитие и последовательное ужесточение тех самых технологических показателей.

Switching to the concept of the technological regulation occurs simultaneously with implementing a number of federal environmental projects including those included in the Ecology National Project. Considering that water utilities, through the spectacle of Rosprirodnadzor are among the main polluters of water bodies, the construction of new and upgrade of the existing treatment facilities is the focus of public authorities, regulators and, naturally, the wastewater facilities operators themselves. The paper considers potential and possible inconsistencies of the current design expectations based on the technological indicators of the best available technologies and the very concept of using the best available technologies that does not imply stasis but the development and consistent tightening of those same technological indicators.