bluuebunny/crossref_metadata_2025 huggingface dataset:
Learning strategies of dental students in Buenos Aires, Argentina prior to and during the COVID-19 pandemic
Authors: Bordoni Noemí , Salgado Pablo A , Argentieri Ángela , Squassi Aldo F
Published: January 2023

Various theories have endeavored to explain how knowledge is accessed. Students, in order to learn, need a good repertoire of appropriate metacognitive and self-regulating strategies and knowledge, which they use consciously or unconsciously. Teachers, in addition to knowing how to teach, need to be aware of students’ learning strategies, metacognition, and self-regulation, and of the impact of changes associated with recent pandemic scenarios. Aim: The aim of this study was to identify the study strategies preferred by dental students in two different scenarios: prior to and during the pandemic. Materials and Method: The sample consisted of third-year dentistry students at Buenos Aires University (UBA) during 2019 (Group GP, 141 students, face-toface activity) and 2021 (Group GE, 60 students, e-learning during the pandemic). Participants were asked (a) to provide demographic information (sex and age) and (b) to answer the abridged ACRA scale. Statistical treatment included descriptive tests; Chi2, binomial exact and Student’s t-test (p<0.05). Results: The proportion of students who participated with respect to total students enrolled was 58.50% in 2019 and 26.20% in 2021, with female gender being significantly higher. There were significant differences in total number of participants during the different periods (p=0.001), and in gender distribution during the pandemic (p=0.007). Comparison between groups GP and GE showed no significant difference regarding preferences expressed in total values for the scale or for the domains. Analysis of preferences according to gender showed significant differences in total group (p=0.007) and the domains CLCS (Cognitive and Learning Control Strategies) (p= 0.008) and LSS (Learning Support Strategies) (p=0.002). The mean values of preferences selected by females were higher. Similar results were found upon analyzing preferences during the pandemic (n= 60) considering total score (p= 0.033) and the domains CLCS (p= 0.035) and LSS (p= 0.007). Conclusions: The study identified trends towards an increase in the score and consequently greater use of techniques included in the domains related to metacognition, especially among women. There is potential neutralization of the impact created by the methodological shift between the two periods (face-to-face and e-learning) probably as a result of the implicit adaptability, latent in students, regarding digital methodology, which enables them to adapt to learning in challenging situations. Keywords: learning strategies - e-learning - gender - COVID-19
The failure on the effectiveness of formalin on cadaver disinfection and alternative methods
Authors: YANILMAZ Ozgur , GUNCU Mehmet Mucahit , AKSU Mehmet Burak , OZKAN Mazhar , SEHIRLI Umit Suleyman
Published: January 2023

Objective: It was aimed to identify the contaminant and determine the alternative disinfectant detection in the microbial growth

observed in various parts of the cadaver stored in the formalin tank in the dissection laboratory of Marmara University Anatomy

Department. We also performed a literature review of this unusual pathogen.

Materials and Methods: Swab samples were inoculated on agar mediums. After incubation, matrix-assisted laser desorption ionizationtime

of flight mass spectrometry (MALDI-TOF MS) analysis was used to identify the isolate from the detected uniform colonies.

Sample solution from the cadaver tank, freshly prepared 5% formalin and 0.55% ortho-phthalaldehyde were used to determine the

disinfectant sensitivity of the isolate.

Results: According to 16s rDNA sequence analysis, it was concluded as Skermanella aerolata with 99% similarity. In the disinfectant

susceptibility test, it was observed that S. aerolata and control bacteria could grow in 5% formalin taken from the cadaver tank. No

growth was detected in other disinfectants.

Conclusion: To prevent cadaver contamination in anatomy laboratories, the quality control of the embalming solutions and indoor

air filtration of the dissection rooms should be checked at regular intervals. Members of Skermanella genus have been identified as

environmental organisms in several studies, however, recent researches reported this bacterium as a human pathogen.
Health behavior and health needs of first-year medical and health sciences students
Authors: GUR Kamer , EROL Saime , GUNES F. Esra , CIFCILI Serap , CALIK K. Burcu , OZER Aysel Yildiz , DEMIRBUKEN Ilksan , POLAT M. Gulden , APAYDIN KAYA Cigdem
Published: January 2023

Objective: The aim of this study is to evaluate the health behavior and health needs of medical and health sciences students in order to identify areas that need intervention. Materials and Methods: This descriptive study was conducted with 770 first-year university students. The data were collected with a sociodemographic questionnaire, the Youth Risk Behavior Survey and the Eating Attitudes Test. Body mass index was calculated. Results: Although, only 12.7% of the students were overweight or obese, 25.6% of the students perceived themselves to be overweight or obese. The students said that in the last week, 20.9% had breakfast 1 or 3 times, 5.7% ate no fruits at all, and 11.6% ate no vegetables at all. 48.1% of the students did not engage in any physical activity, and 83.2% spent more than 2 hours inactively in front of a screen. It was observed that 22.3% were current smokers. A propensity for eating behaviors disorder was found in 9.0%. Drinking energyboosting sports drinks 1-6 times in the last week (β: 3.286), smoking (β: 1.875) and eating few vegetable dishes in the last week (β: 0.484) were identified as factors that could be associated with a “tendency for eating behavior disorder.” Conclusion: We can conclude that nutritional issues, negative body weight perception, use of tobacco, and sedentary lifestyle are the main intervention and counselling areas for our study group.
Medical students’ knowledge of the disease, frequency of depression, anxiety, stress symptoms, and related factors in the COVID-19 pandemic: A web-based questionnaire
Authors: CINAR TANRIVERDI Esra , BAYRAKTAR Mustafa , SINCAN Suat , KASALI Kamber , CAYIR Yasemin , SAHINGOZ Mine , OZKURT Zulal
Published: January 2023

Objective: In this study, it was aimed to determine the level of knowledge of medical students about coronavirus disease 2019 (COVID-19), to investigate the frequency of depression, anxiety, stress symptoms and related factors. Materials and Methods: The study is a cross-sectional study conducted with 904 volunteer medical students. Data were collected with an online questionnaire, including sociodemographic characteristics, knowledge about COVID-19, the Depression, Anxiety, and Stress Scale. Results: Mean age was 21.3±2.2 years, and 54% of them (n=488) were female. Fifty five percent (n=497) thought that their level of knowledge about COVID-19 was sufficient, and 94.6% (n=846) were concerned about the disruption of their education. Their knowledge level was found to be 15.09±2.43 points out of 23 points. The depression, anxiety and stress symptoms were found in 64.9%, 70.4% and 34.1% of participants, respectively. The risk of anxiety (OR=0.51, 95%CI=0.94, p=0.020) and depression (OR=0.95, 95%CI=1.15, p=0.025) were higher in women. Those with a high fear of transmitting the COVID-19 infection to their relatives had higher symptoms of depression, anxiety, and stress. (p
Assessment of the Efficiency of Public Administration
Authors: Orlova Nataliia , Lukashuk Mykola
Published: January 2023

The chapteris devoted to the study of methods of analysis and evaluation of the effectiveness of public administration in global and European integration dimensions to determine the direction of further transformations in the public administration of Ukraine in the process of implementing the state policy of Ukraine. Priority goals of effective governance in Ukraine were determined, international and European indices for assessing the quality and efficiency of public administration were analyzed according to various indicators and signs (Global Competitiveness Index, The World Competitiveness Yearbook, Governance Research Indicator Country Snapshot, Sustainable Governance Indicators, Bertelsmann Transformation Index, Democracy Index, Open Government Index, Corruption Perceptions Index, SIGMA). The conclusions are substantiated the further directions of transformations of public administration in Ukraine in the post-war period for the implementation of the strategy of reforming public administration, which will allow speed ingup the process of European integration.
Innovative Trends in the Creation of Rocket and Spacecraft Equipment for the Purpose of Enhancement of National Security
Authors: Koshova Svitlana
Published: January 2023

The space industry has grown and evolved significantly over the past six decades. Exploitation of space under the auspices of several space states has become an activity in more than 60 countries around the world. For its financing, in addition to state capital, the private sector began to be actively involved in the form of investment resources, which made it possible to increase the pace of its development several times. In recent years, interest in space exploration and the benefits that can be, derived from it has grown significantly. This became possible due to the significant simplification of travel beyond the borders of the Earth under the influence of innovative trends. Therefore, the current trends in the global space industry are, defined in the scientific study. The role of the space sphere in the general development of the country and the formation of its competitive advantages has been, established. The key directions of space travel in our time are outlined, and the role of reusable launch systems for orbital vehicles in their actualization. Described the SN20 reusable launch system developed by SpaceX as a basis for creating opportunities for travel to Mars. Its technical characteristics and the sequence of its licensing procedure for the first launch are, defined. The dynamics of changes in the cost of rocket launches under the influence of innovations were, studied. The reasons for the resumption of trips to the Moon are established, a parallel is, drawn between, the influence, of such trips on the further colonization of Mars. The current trends in the field of satellite launches have been determined, the number of orbital launch attempts by countries has been, analyzed, and the forecast for changes in the number of satellites until 2030 has been determined. The problem of combating space debris, which remained from past missions and will remain from future missions, was, studied. Directions for using space technologies to fight global warming are, defined. Ways of using 3D printing for the needs of future space missions are, analyzed. The structure of the direction of venture capital in space technologies in terms of the countries, as well as in terms of the stages of implementation of space projects in terms of value and quantity, were, studied.
I’m an Optimist and I Know I’ll Always Succeed. Interview with Roman Aranin
Authors: Vyatkina Yu.
Published: January 2023

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Social Impact Projects in Russia: First Results of 2022
Authors: Manuilov N.
Published: January 2023

By the end of 2022, Social Impact Projects in Russia (SIPs), aka Social Impact Bonds (SIBs), were 2/3 of the way through pilot testing. The new financial instrument designed to improve the quality of public services was approved by a special resolution of the Russian Government in 2019. The first three projects implemented on the SIB model have already been completed to date. What are the tasks addressed by SIPs in Russia, what are their features, what changes in the quality of life do they bring to our citizens, and who can they become an inspiration to? More on that in this article by a VEB.RF expert.
Green Human Resource Management. Assessing the Impact on the Environmental Sustainability of Banks (Nigeria Case Study)
Authors: Aker Holo Matthew , Suleiman Abubakar Sadiq
Published: January 2023

As the ESG agenda is gaining popularity around the world, companies start paying more and more attention to environmental responsibility, striving to reduce ecological damage. Green human resource management practices are becoming part of corporate strategies. For example, this means electronic workflow, from online vacancy announcements to employee training to use the resources sparingly and to conserve energy. In this article, we discuss the effects of “green” HR on the environmental sustainability of banks in Katsina State, Nigeria.
Prevalensi Trikomoniasis pada Wanita Risiko Tinggi di Kawasan Wisata Baturraden Kabupaten Banyumas
Authors: Widyastuti Sri , Setya Adhi Kumoro
Published: January 2023

Trikomoniasis merupakan penyakit menular seksual yang cukup tinggi angka kejadiannya. Orang  dengan pekerjaan bergonta ganti pasangan seksual, diyakini sebagai faktor penularan utama. Dalam beberapa tahun terakhir penderita infeksi menular seksual di Banyumas menunjukan angka yang cukup tinggi. Keberadaan Gang Sadar yang merupakan kediaman wanita penjaja seks, dengan lokasi yang strategis serta dekat dengan tempat wisata di Baturraden, membuat banyak orang berkunjung. Kondisi tersebut meningkatkan risiko penularan trikomoniasis dikawasan tersebut. Tujuan penelitian ini adalah untuk mengetahui berapa besar kasus trikomoniasis pada sampel urin wanita risiko tinggi di kawasan wisata Baturraden. Penelitian ini bersifat deskriptif dengan melibatkan responden penelitian wanita dengan pekerjaan berisiko tinggi. Pada setiap responden penelitian dilakukan pemeriksaan dari spesimen urinnya dan sebagai pendukung dilakukan pengambilan data prihal latar belakang kehidupan responden. Data disajikan dalam tabel dan dihitung persentase responden yang terinfeksi Trichomonas vaginalis. Dari hasil pemeriksaan laboratorium ditemukan parasit Trichomonas vaginalis sebanyak 2 orang dari 30 responden penelitian. Berdasarkan data sosiodemografi, temuan kasus terjadi pada responden dengan karakteristik; umur diatas 21 tahun, pendidikan terakhir SMP dan SMA, profesi pemandu karaoke dan PSK serta status perkawinan belum menikah dan cerai. Dari data aktifitas seksual responden, muncul dengan karakteristik; semua menunjukan gejala keputihan dan bau tidak normal serta melayani 1-3 pelanggan perhari. Hasil penelitian ini didapatkan kesimpulan bahwa kasus trikomoniasis sebesar 6,7% dengan karakteristik responden heterogen.
Total Kapang Khamir dan Identifikasi Bakteri Patogen pada Sediaan Jamu Tradisional
Authors: Prabandari Anggraeni Sih
Published: January 2023

Jamu tradisional rentan mengalami kontaminasi kapang/khamir dan bakteri, berasal dari bahan baku dan proses produksi yang sederhana dan belum terstandar. Regulasi BPOM RI tahun 2014 mengatur tentang syarat mikrobiologis produk jamu tradisional. UMKM X di Kota Surakarta memproduksi empat varian jamu tradisioanal yang dijual di Kota Surakarta dan Sekitarnya. Penelitian ini bertujuan untuk menganalisa cemaran kapang/khamir, identifikasi spesies kapang dan identifikasi keberadaan bakteri patogen. Jenis penelitian adalah deskriptif dengan pendekatan cross sectional. Sebanyak empat varian jamu (beras kencur, kunyit asam, jahe rempah dan temulawak) diambil secara random dan diperiksa. Total cemaran kapang/khamir dihitung dengan metode Angka Kapang Khamir (AKK), sedangkan identifikasi bakteri (Escherichia coli dan Staphylococcus aureus) diidentifikasi berdasarkan sifat pertumbuhannya pada media selektif diferensial. Hasil penelitian menunjukkan seluruh sampel memiliki nilai AKK >103 koloni/ml dan tercemar Escherichia coli. Hasil identifikasi kapang ditemukan spesies Aspergillus flavus dan Aspergillus niger. Sebanyak 80% sampel jamu yang diperiksa tercemar Staphylococcus aureus. Oleh karena itu, seluruh sampel jamu yang diperiksa tidak memenuhi standar BPOM RI tahun 2014.
Penatalaksanaan Pijat Oketani dan Kompres Daun Kubis dengan Masalah Ketidakefektifan Pemberian Asi pada Ibu Post-Partum di Kelurahan Bulakrejo
Authors: Prastiwi Anggita Dwi , Rahayuningsih Tutik
Published: January 2023

Masa nifas merupakan masa pemulihan dimulai setelah plasenta lahir dan berakhir ketika rahim kembali ke keadaan sebelum hamil. Perubahan fisiologis yang terjadi pada masa nifas salah satunya adalah laktasi, seperti adanya bendungan ASI. Salah satu upaya untuk mengatasi bendungan ASI yaitu dengan pijat oketani dan kompres daun kubis. Penelitian ini bertujuan pendeskripsikan penatalaksanaan pijat oketani dan kompres daun kubis dengan masalah ketidakefektifan pemberian ASI pada ibu post-partum. Desain penelitian deskriptif kualitatif menggunakan studi kasus (case study research) dengan pendekatan proses keperawatan. Teknik pengambilan subjek non-probability sampling dengan pendekatan purposive sampling. Data penelitian didapatkan ASI belum keluar, payudara penuh dan nyeri, ibu merasa belum berhasil menyusui, rooting reflek lemah, kedua payudara tampak tegang, puting masuk kedalam dan kotor, terdapat bendungan ASI, nyeri tekan pada kedua payudara, pengeluaran ASI 0cc. Diagnosa keperawatan ketidakefektifan pemberian ASI berhubungan dengan suplai ASI tidak cukup. Tindakan keperawatan pijat oketani dan kompres daun kubis selama tujuh hari, setiap pagi dan sore hari selama 20-30 menit. Evaluasi tindakan pijat oketani dan kompres daun kubis dapat meningkatkan  produksi ASI dari 0cc menjadi 80-120cc. Tindakan pijat oketani dan kompres daun kubis dapat mengatasi masalah keperawatan ketidakefektifan pemberian ASI berhubungan dengan suplai ASI tidak cukup.
Yarı Kurak İklim Şartlarına Sahip Olan GAP Bölgesinde Bazı Pamuk (Gossypium hirsutum L.) Çeşitlerinin Verim, Verim Ögeleri ve Lif teknolojik Özelliklerinin Belirlenmesi
Authors: YILMAZ Ahmet , CEVHERİ Cevher İlhan , OK Davut
Published: January 2023

Bu çalışma, 2018 yılında Yarı kurak iklim koşullarının hüküm sürdüğü Diyarbakır İlinde yürütülmüştür. Çalışmada; farklı kurumlardan temin edilen bölge tarımına yeni alınan 9 pamuk çeşidi (Bomba, Carla, Edessa, Es 1, Esperia, Lima, SC 2009, SC 2079, Sezener 76, PG 2018) ile 6 pamuk çeşidi (BA 119, BA 440, Gloria, Carla, DP 499, ST 468) materyal olarak kullanılmıştır. Tesadüf blokları deney desenine göre üç tekerrürlü olarak kurulan çalışmada, her parsel 10 m boyunda, 4 sıralı, sıra arası 70 cm ve sıra üzeri mesafe 10 cm olacak şekilde ekim gerçekleştirilmiştir. Çalışmada, bitki boyu, odun dalı sayısı, meyve dalı sayısı, koza sayısı, ilk meyve dalı boğum sayısı, dekara kütlü pamuk verimi, çırçır randımanı, 100 tohum ağırlığı, lif uzunluğu, lif inceliği ve lif mukavemeti incelenmiştir. Araştırmadan elde edilen sonuçlara göre; Çeşitler arasında kütlü pamuk veriminin 307.0 ile 507.0 kg/da arasında değiştiği saptanmıştır. Bitki boyu yönünden ES-1, meye dalı sayısı yönünden SC 2009, Kütlü pamuk verimi yönünden DP 499, çırçır randımanı yönünden ES-1 ve ST 468 (%41.60) ve Lima (%41.47) 100 tohum ağırlığı yönünden Sezener-76, lif uzunluğu yönünden Lima, kısa lif oranı yönünden DP 499, lif elastikiyeti yönünden Bomba, lifte sarılık yönünden Gloria çeşitlerinin diğer çeşitlerden üstün oldukları belirlenmiştir. Ayrıca, ilk meyve dalı boğum sayısı, odun dalı sayısı, açan koza sayısı, açmayan koza sayısı, lif inceliği, üniformite, lif kopma dayanıklılığı, parlaklık değeri yönünden çeşitler arasında istatistiksel olarak önemli bir fark olmadığı tespit edilmiştir.
STAJA GİRİŞ SINAVI SONUÇLARI IŞIĞINDA MALİ MÜŞAVİRLİK MESLEĞİNE YÖNELİK YÜKSEKÖĞRETİM PROGRAMLARI ÜZERİNE BİR DEĞERLEME
Authors: YÜKSELEN Cemal
Published: January 2023

Sayıları artan üniversitelerimiz ve sosyal bilimler alanlarındaki bölümlerimiz ile iş hayatına her yıl çok sayıda mezun katılmaktadır. Ancak çeşitli platformlarda iş insanları ve insan kaynakları yöneticileri, aranan niteliklere uygun personel bulmada sorunlarla karşılaştıkları ve bilgi ve yetkinliklerin yeterli olmadığı şeklinde görüşlerini dile getirmektedirler. Bu bağlamda TÜRMOB’un yürütmekte olduğu Serbest Muhasebeci Mali Müşavir olma sürecinin ilk adımı olan Staja Giriş Sınavı, lisans mezunlarının bu alandaki bilgilerini ölçmede önemli bir araç olarak görülmektedir. Yılda üç kez yapılan sınavlara 3568 sayılı Kanuna uygun bölümlerden her dönem en az 17 bin mezun katılmaktadır. Bu çalışmanın amacı, söz konusu sınavlarda mezunların başarı puanlarının analitik bir değerlemesini yaparak lisans öğrenimine ilişkin durum saptaması yapmak ve önerilerde bulunmaktır. Örnek olarak alınan 2021 yılında yapılan sınav sonuçları üzerinden elde edilen analiz sonuçları, lisans öğreniminin, günümüz koşullarına ve iş dünyasının beklentilerine uygun şekilde gözden geçirilmesi gerekliliğini ortaya koymaktadır.
A Generalization of Projective Module
Authors: - Fitriani , Wijayanti Indah Emilia , Faisol Ahmad
Published: January 2023

Let $V$ be a submodule of a direct sum of some elements in $\mathcal{U}$, and $X$ be a submodule of a direct sum of some elements in $\mathcal{N}$, where $\mathcal{U}$ and $\mathcal{N}$ are families of $R$-modules. A $\mathcal{U}$-free module is a generalization of a free module. According to the definition of $\mathcal{U}$-free module, we define three kinds of projective$_{\mathcal{U}}$ in this research, i.e., projective$_{\underline{\mathcal{U}}}$, projective$_{\mathcal{U}}$ module, and strictly projective$_{\mathcal{U}}$ module. The notion of strictly projective$_{\mathcal{U}}$ is a generalization of the projective module. In this research, we discuss the relationship between projective modules and the three types of modules. Furthermore, we show that the properties of $\mathcal{U}$ impact the properties of the projective$_{\mathcal{U}}$ module so that we can determine some properties of the projective$_{\mathcal{U}}$ module based on the properties of the family of $\mathcal{U}$ of $R$-modules.
Determinants for successful loan credits for older people in Thailand
Authors: Sringernyuang Luechai , Torut Buraskorn , Felix Mark Stephan , Vongjinda Saisuda , Chaimongkol Ubonwan
Published: January 2023

Aging populations are gradually creating financial distress for governments, and Thailand is no exception. Effective policies for improving elderly welfare must be formulated since the population shift to older age is moving at a faster pace than economic growth. Older people prefer to live actively and independently in order to be less burdensome to their family members and are actively engaged in activities, either voluntarily or because of necessity, even after retirement age. The Thai government initiated a microcredit scheme for eligible older people in order to overcome the difficulty of gaining access to credit. The objective of this research is to explore and evaluate the effectiveness of the Older Persons Fund (OPF) organized by the Thai government to provide seed money for loans to promote active aging in Thailand. Data were collected nationwide using stratified sampling in urban and rural districts from members affiliated with the Older Persons Fund. Structured interviews were conducted with 578 loan recipients. The methodology includes inferential statistics and the multinomial logit choice probabilities model to determine the factors for successful active aging of the loan recipients. The results indicate that the purpose of the loan is a significant factor for a successful outcome. The results also imply that older people provide input into the economy and are not a burden on government expenditure in the long run by promoting active aging projects through microcredit schemes in Thailand.
Empirical assessment of the environmental Kuznets curve hypothesis in Indonesia, Malaysia, the Philippines, and Thailand using the ARDL and FMOLS techniques
Authors: Takashi Fukuda
Published: January 2023

The purpose of the present paper is to empirically investigate whether the environmental Kuznets curve (EKC) hypothesis is validated for Indonesia, Malaysia, the Philippines, and Thailand over the period of 1971-2014. The estimation techniques employed are the autoregressive distributed lag (ARDL) and the fully modified ordinary least square (FMOLS), and we conduct the Granger causality tests to draw interpretation. We take CO2 emissions as the dependent variable, and those endogenous variables of economic growth, the square of economic growth, energy consumption, trade openness, and foreign direct investment (FDI), together with the structural break dummy (for the ARDL estimation only). The EKC hypothesis is statistically confirmed for Thailand by both the ARDL and FMOLS estimations, but it is not so for Indonesia, Malaysia, the Philippines. One policy implication is that, regardless of whether the EKC hypothesis is confirmed or not, the four ASEAN countries are required to ensure the compatibility between economic growth and environmental improvement by persistently proposing and implementing effective policies to fight against environmental degradation. Another implication is that, policymakers should consider how to convert their countries from pollution heaven countries to environmentally-friendly ones, correctly evaluating the impact of globalization on economic growth and environmental degradation.
ANALYSIS OF COMMON SOMATIC MUTATIONS IN COLORECTAL CARCINOMA AND ASSOCIATED DYSREGULATED PATHWAYS
Authors: Hassan Sobia , Khatoon Ambrina , Bukhari Uzma , Mirza Talat
Published: January 2023

Background: Identification of gene targets and biological pathways involved in colorectal carcinoma (CRC) is essential for better management of patients. Our study aims to highlight common somatic mutations in colorectal carcinoma and to identify dysregulated pathways and gene enrichment based on KRAS and BRAF interaction network analysis. Methods: By using cancer browser tool in COSMIC database, mutation frequencies of the top 20 mutated genes listed for colorectal adenocarcinoma were identified. The most frequent variants of   selected genes were explored with ClinVar database which led to identification of protein change along with its cytogenic location, variant type, variant length and the associated single nucleotide polymorphism (SNP). These identified SNPs were searched in Pakistani database using 1000genome in an attempt to identify common polymorphisms. Using the database ClinicalTrial.gov the number of clinical trials based upon these selected mutations was explored. Enrichment and protein interaction (PI) analysis of KRAS and BRAF was carried out to reveal significant biological pathways associated with these genes. Results: In cumulative data, among all variants about 57% of substitution mutations are observed to be G>A including mutations in KRAS, Tp53, SMAD4, PI3K and NRAS. The mutations of KRAS (c.35G>A), TP53 (c.524G>A) and APC (c.4348C>T) were found to be pathogenic with single nucleotide variation and variant length of 1bp. Searching 1000genome database revealed that  100 % of alleles found in East Asian population  studied  are ‘C’(frequency=1). Significant biological pathways (<0.05) identified by our search include Trk receptor signalling mediated by the MAPK pathway, signalling to p38 via RIT and RIN, signalling to ERKs, Frs2-mediated activation, ARMS-mediated activation and prolonged ERK activation events. Conclusion: Our study highlights the role of genetic profiling in CRC, with emphasis on mutations which may define treatment outcome. Targeting several collateral pathways simultaneously may be further explored to improve colorectal cancer therapeutics.
MARKED ACANTHOCYTOSIS ASSOCIATED WITH KLIPPLE-TRENAUNAY SYNDROME
Authors: Ali Syeda Mah , Raza Naila , Aftab Eraj , Faisal Mohammad Mahnoor
Published: January 2023

Klipple-Trenaunay syndrome (KTS) is an extremely rare congenital vascular disorder with poorly defined incidence and prevalence. We report a case of a patient who presented after road traffic accident with primary complaints of poor wound healing and persistent bleeding from wound site. Discernible presence of arteriovenous malformation and skin hypertrophy since birth lead to the diagnosis of Klipple-Trenaunay syndrome (KTS). There was an incidental finding of acanthocytosis on peripheral film of blood which remained elevated even after clinical improvement of the patient. This case report highlights a close association of marked acanthocytosis of red blood cells and Klipple-Trenaunay syndrome.
Bailey, Gino i Espinosa, Felipe (2022). La ciudad de los lugares posibles
Authors: Sala Eduard
Published: January 2023

Bailey, Gino i Espinosa, Felipe (2022)La ciudad de los lugares posiblesBarcelona: Hermenaute, 300 p.ISBN 9788412326949
Casellas, Antònia (ed.) (2022). J. K. Gibson-Graham: Hacia una economía postcapitalista o cómo retomar el control de lo cotidiano
Authors: Ortiz Guitart Anna
Published: January 2023

Casellas, Antònia (ed.) (2022)J. K. Gibson-Graham: Hacia una economía postcapitalista o cómo retomar el control de lo cotidianoBarcelona: Icaria, Espacios Críticos, 252 p.ISBN 978-84-18826-62-7
Romance grammars in context and contact
Authors: Corr Alice , Schifano Norma
Published: January 2023

This Special Issue brings together ten articles authored by the participants and invited speakers of the Romance Grammars, Context and Contact (RGCC2021) workshop. This introductory article provides an overview of the workshop and summarizes the articles in the present collection.
'Doing' Romance Linguistics
Authors: Toribio Almeida Jacqueline
Published: January 2023

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A STUDY ON PREFERENCES OF CONSUMERS TOWARDS INTERNATIONAL OTT PLATFORMS AND SUSTAINABILITY STRATEGY IN INDIAN MARKET
Authors: Sharma Anil , Harsora Hiren
Published: January 2023

There are several social benefits generated by digital platforms, including facilitating inclusion. Communication services have been critical in accelerating the inclusion of marginalized users into formal systems, particularly for financial, health, and education services that are enabled by OTT providers. Using OTT platforms places a significant strain on energy resources, services providing music and video streaming have a far lower carbon footprint than traditional physical formats.

Over The Top (OTT) industry is one of the fastest growing industries in the world. The usageofOTTplatformsinIndiahastremendouslyincreasedafterCOVID19.ThereasonsforthisismobilefriendlyandtheoriginalcontentthattheseOTTplatformsprovide.In India, big international players like Netflix entered and changed the entertainment industry making platform for more international as well as Indian OTT platforms. This study focuses on various international OTT platforms in India and their performance in Indian Market. The study attempts to identify current international OTT platform trends with reference to type of shows preferred by customers & investigate OTT platform success factors in India. The research concluded that majority of the people preferred Netflix, followed by Disney+ HotStar and Amazon Prime Video. The respondent’s shows liking towards OTT which focus more on Original Shows and Web Series which gets frequently updating list just like Netflix. It was also observed that Disney+ HotStaris more preferred as they of digital broadcasting partner for big cricket events like IPL and World Cup. The research concludes that localization of content, affordable pricing, high quality picture quality, strong distributorship partnership, good user experience and better after sales services are the major factor for success of international OTT in Indian Market.
METODOLOGÍA ÁGIL EN LA GESTION HUMANA
Authors: BROCE ANGELICA , GUTIERREZ THAYRINE , JIMENEZ GISELLE
Published: January 2023

En el área de administración de la gestión humana, es importante implementar métodos que sean eficientes en relación con las tendencias y mejores prácticas que surjan y aporten un real valor, ya sea para emprender un proyecto, y más importante aún, para transformar la cultura de nuestras organizaciones hacia una era más eficiente y ágil. El ámbito VUCA en el que vivimos actualmente, ha impactado la manera en la que las organizaciones deben operar para ser más competitivos y ganarse un lugar en el mercado actual. Esto ha provocado el tener que adecuar sus procesos rígidos a formas de trabajo flexibles, participativas, democráticas y eficientes para poder llevar cabo sus proyectos de manera más ágil, en busca de resultados en un menor tiempo que el habitual. Es aquí donde toman una gran relevancia las llamadas metodologías ágiles, que vienen a romper paradigmas y a una gran variedad de beneficios al sector empresarial.

Aunque la metodología agile nace con el objetivo de mejorar los procesos empleados para el desarrollo de proyectos de software y así obtener resultados en menor tiempo, tomando en cuenta la opinión del cliente en relación a los prototipos durante el desarrollo de los mismos, su efectividad ha provocado interés para ampliar su ámbito de aplicación hasta el área de RRHH, desde procesos de reclutamiento, mejora de rendimiento de la organización entre otros. Para enfocarnos en la competitividad y su importancia en la era post covid, nos enfocaremos en la metodología agile como herramienta de mejora del rendimiento de equipos en las organizaciones y su positivo impacto en procesos de atracción, retención del talento, resolución de problemas, reforzamiento de la marca empleadora, entre otros.
Analisa Kinerja Keuangan, Kebijakan Dividen dan Pertumbuhan Aset Terhadap Return Saham Perseroan
Authors: Perbanas Institute Yohanes Ferry Cahaya , Sekolah Tinggi Ilmu Ekonomi Y.A.I Sofa Yulandari
Published: January 2023

Dalam suatu perusahaan yang telah go public penting untuk diketahui bahwa pergerakan sahamnya sekecil apapun, karena semakin meningkatnya return saham suatu perusahaan akan semakin menarik minat investor untuk menanamkan modalnya ke dalam perusahaan tersebut. Penelitian ini bertujuan untuk menguji faktor-faktor yang mempengaruhi return saham, yang dapat dinilai dari kinerja keuangan, kebijakan dividen dan pertumbuhan aset. Penelitian ini menggunakan data sekunder dari 6 sampel laporan keuangan perusahaan perbankan dan pengambilan sampel menggunakan teknik purposive sampling. Uji asumsi klasik dalam penelitian ini meliputi uji normalitas, uji multikolinearitas dan uji heterokedastisitas. Analisis data menggunakan analisis regresi linier berganda, uji t, uji f, dan uji koefisien determinasi. Analisis data menggunakan eviews 9. Hasil penelitian ini kinerja keuangan berpengaruh signifikan terhadap return saham ditunjukkan dengan tstatistik 2,675175 dan signifikan 0,0127 < 0,05, kebijakan dividen tidak berpengaruh terhadap return saham ditunjukkan dengan tstatistik 0,210132 dan signifikan 0,8352 > 0 ,05, dan pertumbuhan aset berpengaruh signifikan terhadap return saham ditunjukkan bt tstatistic 2,627618 dan signifikan 0,0142 < 0,05. pada perusahaan perbankan yang terdaftar di Bursa Efek Indonesia (BEI), hasil secara simultan (uji f) Fstatistik > Ftabel atau 4,352762 > 2,99 dan 0,013011 < 0,05 menunjukkan pengaruh yang signifikan terhadap kinerja keuangan, kebijakan dividen dan pertumbuhan aset atas pengembalian saham pada perusahaan perbankan yang tercatat di Bursa Efek Indonesia (BEI).
SARS-CoV-2 y su relación con enfermedades isquémicas en adultos.
Authors: Lino Lino Karen Ariana , Helen Tamara Preciado Valencia , Castro Jalca Alexander Darío
Published: January 2023

La infección por el SARS-CoV-2 se ha convertido en uno de los actuales retos a los sistemas de salud de todo el mundo, causando una crisis que impactó a la población mundial, por su parte las enfermedades isquémicas se refieren al conjunto de afectaciones a los vasos sanguíneos, debido al daño cardiovascular. Este trabajo tuvo como objetivo el evaluar la relación del SARS-CoV-2 y enfermedades isquémicas en adultos. Se aplicó en la investigación un diseño documental narrativo de tipo descriptivo, se empleó como estrategia de búsqueda un análisis exhaustivo de documentos fiables que presentaron la información requerida en diferentes bases de datos de carácter internacional y nacional, aplicando criterios de inclusión y exclusión. Se determinó los índices de morbilidad presentados en los diversos estudios dado que son variables entre el 51.2% por la COVID-19 y 64.7% por enfermedades isquémicas siendo los adultos mayores el grupo vulnerable, los pacientes afectados presentaron niveles altos de marcadores séricos de trombosis e inflamación, como dímero D, fibrinógeno y proteína C reactiva, Troponina, así como niveles elevados de citoquinas inflamatorias, la presencia de factores de riesgo como hipertensión arterial, diabetes mellitus y daño cardiaco  incrementaron la morbimortalidad de los pacientes adultos, principalmente en hombres y hace que los esfuerzos de los sistemas de salud se incrementen, es por esto que este tipo de investigaciones deben ser ampliadas para conocer de manera más especifica el nivel de afectación de la población que tiene mayores probabilidades de sufrir estas enfermedades.
Enfermedades cardiovasculares y metabólicas en pacientes infectados por el Virus de Inmunodeficiencia Humana: Epidemiología y diagnóstico.
Authors: Aveiga Bartolome Yaritza Lissethe , Torres Indacochea Gabriela Nicole , Valero Cedeño Nereida Josefina , Merchán Villafuerte Karina Maricela
Published: January 2023

El virus de inmunodeficiencia humana fue nominado como la causa primaria del síndrome de inmunodeficiencia adquirida, en el año de 1984 se presentó el primer caso en Ecuador. Con ello se desarrollaron diversas enfermedades asociadas a la misma, entre ellas la enfermedad cardiovascular y metabólica, teniendo su origen en una compleja red de interacciones de factores asociados al virus, el huésped y la terapia antirretroviral. El objetivo de la investigación fue analizar evidencias científicas sobre la epidemiología global de las enfermedades cardiovasculares y metabólicas en pacientes infectados por el Virus de Inmunodeficiencia Humana. Se realizó un estudio de diseño documental con revisión sistemática, de tipo descriptivo y exploratorio, bases de datos científicas PubMed, SciELO, Ecuador, Google Académico y Elsevier. Se utilizaron artículos publicados desde hace 5 años, también palabras clave y términos MeSH: “enfermedad cardiovascular”, “virus de inmunodeficiencia humana”, “Enfermedades metabólicas”, “síndromes metabólicos”, “dislipidemias”, “sistema inmunitario e infección por virus de inmunodeficiencia humana”. se aplicaron criterios de selección basados en la relevancia y centradas en la temática. Existen muchos factores de riesgo los cuales pueden ser causantes para el desarrollo de enfermedades cardiovasculares y metabólicos en pacientes infectados por el virus de inmunodeficiencia humana, entre estos factores están el sobrepeso, hipertensión arterial, tabaquismo, colesterol de baja densidad elevado, colesterol de alta densidad bajo, entre otros, siendo un motivo especial de preocupación en los pacientes infectados por el virus, dada la mayor probabilidad de complicaciones debido al déficit que tienen en su sistema inmunitario.
Biometrical approaches for selection of parents in vegetable cowpea (Vigna unguiculata) breeding programme
Authors: LAL HIRA , RAI NAGENDRA , NATH VISHWA
Published: January 2023

Eighty nine genotypes of vegetable cowpea collected from different parts of India were evaluated for yield and yield-attributing traits for genetic variation, character association, cause-effect analysis and genetic diversity among the genotypes through D2 statistics. High values of genotypic and phenotypic coefficient of variations, broad sense heritability and genetic advance were estimated for plant height, pod yield/plant, number of peduncles and pods/plant, pod weight and pod length. Pod yield/plant showed strong positive correlation with pod weight, number of peduncles and pods/plant, pod length and number of seeds/pod, while negative correlation with days to 50% flowering at genotypic and phenotypic levels. The maximum direct positive effect on pod yield/plant was contributed by pod weight followed by number of pods/plant. Based on degree of divergence the genotypes were grouped into twelve clusters. The genotypes of cluster XII showed maximum genetic divergence with cluster X, hence, crossing between genotypes within these groups could produce good recombinants and desirable segregants. Cluster III was found to be the best performing for number of pods/plant, pod weight and pod yield/plant while the cluster IX flowered much earlier. Thus, crossing between genotypes within these groups could produce desirable transgressive segregants for earliness and high yielding genotypes. Plant height contributed highest towards divergence (29.37%) followed by number of peduncles/plant (26.30%), number of pods/plant (18.39%) and pod weight (16.42%) among vegetable cowpea genotypes.
Improvement of physiological and productivity traits of Indian mustard (Brassica juncea) through micro-irrigation and fertigation under hot semi-arid eco-region
Authors: RATHORE S S , SHEKHAWAT KAPILA , KANDPAL B K , PREMI O P
Published: January 2023

The efficient irrigation and nutrient management was done through micro-irrigation along with fertigation and the effect was evaluated on gas exchange traits, photosynthesis, growth, yield attributes and seed productivity of Indian mustard [Brassica juncea (L.) Czernj and Coss).] crop during rabi season of 2010-11 and 2011-12 respectively, under semi arid conditions. The micro-sprinkler system (MS), drip irrigation (DS) and check basin (CB) irrigation systems were experimented with variable N fertigation levels (0, 40, 80 and 120 kg/ha). The micro irrigation systems, i.e. MS, DS significantly influenced dry weight, chlorophyll concentration, photosynthetic rate, internal CO2 concentration (ICC), primary and secondary branches, main shoot length, total siliquae and 1000 seed weight. Micro-sprinkler irrigation (MS) irrigated mustard was observed on an average increase of 34 % and 23 % increase in seed yield was resulted due to drip irrigation over the two years. N-fertigation from N0 to N120 had significantly improved mustard yield attributes, seed and oil yield. Micro irrigations were also found economically viable option for irrigation in Indian mustard because of higher B: C ratio. Improvement in growth, physiological and yield attributes of mustard were ultimately enhanced seed and oil yield, irrigation water use efficiency, sustainability, yield index and production efficiency. Thus micro irrigation systems at every level of N fertigation out yielded the effect of check basin irrigation.
IMPLEMENTASI CODEIGNITER FRAMEWORK DALAM APLIKASI E-VOTING PEMILIHAN KETUA KELAS BERBASIS WEBSITE
Authors: Syalis Ibnih Melati Istini  , Irsan Zuhri Harahap
Published: January 2023

The rapid development of internet technology is in line with the development of information technology. By using a browser, both mobile and desktop-based devices, information can be obtained easily in a short time. Elections with a voting system are elections that contain judgments or decisions in selecting an object. At present, the general election system for organizations still uses a conventional voting system using ballots which has several weaknesses but these weaknesses can be overcome by implementing electronic voting Information Technology which can be used by all groups or small organizations, and is useful for reducing unnecessary administrative costs. requires ballot papers and reduces time in the vote counting process, based on these problems a literature study is carried out, designing the appearance and flow of the program, implementing the design results into PHP programming language codes structured into the CodeIgniter framework, and conducting application testing. The final results show that the E-voting website application can be used as an alternative during general elections by all organizations that will hold elections. The Prefect Election E-voting website can be accessed via http://evoting3ka06ug.infinityfreeapp.com/.
Ways to increase competitiveness in the field of forensic examination of Azerbaijan and countries of the world
Authors: Nail Ibad Abbasov
Published: January 2023

Application of special knowledge in the process of detection and investigation of crimes, ensuring the right to defense or in the process of representation of victims' rights has a special importance in building a legal and democratic society in Azerbaijan. Crime has acquired new, qualitative characteristics, has become professional, armed and organized. Therefore, forensic activities have become indispensable tools in the process of legal proceedings, in which criminal justice has a special place. The scientific study of the problems of increasing the competitiveness of forensic expertise of Azerbaijan and the countries of the world, is the topical task of the article. The purpose of the scientific study is to identify objective and subjective reasons for the lack of competitiveness of forensic expertise in the Azerbaijan, in comparison with other world leaders. To achieve the goal of scientific research a system of philosophical, general scientific and special scientific methods (comparison, description, analysis and synthesis, induction, deduction and analogy, abstraction, generalization, systematic approach and others) was used. The article examines the theoretical, regulatory and practical problems of ensuring the competitiveness of forensic activities in Azerbaijan. It was found out that the competitiveness of forensic activities was not properly ensured due to the imperfections of the current legislation in Azerbaijan. As a result of the study, it was proposed to introduce amendments to the current legislation, which would allow not only state, but also non-state (private) enterprises and independent experts to carry out forensic examinations
Diseño de una máscara con doble flujo para la reducción de la retención de Co2 y protección ante el Covid -19 en Pucallpa Ucayali
Authors: Esteban Robladillo Isabel , Hernandez Panduro Otilia , Tafur Flores Nelly Graciela , Torres Vargas Eldalaine , Ramirez Chumbe Isabel , Mayma Alvarado Judith Milagros , Zeña Rubio Jenny Paola , Reategui Ramos Paul Kevin
Published: January 2023

El año 2020 fue el inicio de la Pandemia del Covid-19, esta fue generado por un virus de la familia de los Corona-V, los primeros brotes masivos se dieron en el país Chino, en el distrito de Wuhan notificado por primera vez como alerta de virus pandémico el 31 de diciembre del 2019. La enfermedad por coronavirus (COVID‑19) es una enfermedad infecciosa provocada por el virus SARS-CoV-2. Esta pandemia tuvo un saldo mortal de 5.78 millones de fallecidos y más de 403 millones casos confirmados. La mayoría de las personas que padecen COVID‑19 sufren síntomas de intensidad leve a moderada y se recuperan sin necesidad de tratamientos especiales. Sin embargo, algunas personas desarrollan casos graves y necesitan atención médica. El virus puede propagarse desde la boca o la nariz de una persona infectada en forma de pequeñas partículas líquidas que expulsa cuando tose, estornuda, habla, canta o respira. Estas partículas pueden ser desde pequeños aerosoles hasta gotitas respiratorias más grandes. Puedes contagiarte de COVID‑19 si respiras cerca de una persona infectada o si tocas una superficie contaminada y, seguidamente, te tocas los ojos, la nariz o la boca. El virus se propaga más fácilmente en espacios interiores o en aglomeraciones de personas.