bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic diversity and core subset selection inex situseed collections of the banana crop wild relativeMusa balbisiana
Authors: Bawin Yves , Panis Bart , Vanden Abeele Samuel , Li Zhiying , Sardos Julie , Paofa Janet , Ge Xue-Jun , Mertens Arne , Honnay Olivier , Janssens Steven B.
Published: November 2019

Crop wild relatives (CWRs) play a key role in crop breeding by providing beneficial trait characteristics for improvement of related crops. CWRs are more efficiently used in breeding if the plant material is genetically characterized, but the diversity in CWR genetic resources has often poorly been assessed. Seven seed collections ofMusa balbisiana, an important CWR of dessert and cooking bananas, originating from three natural populations, two feral populations and twoex situfield collections were retrieved and their genetic diversity was quantified using 18 microsatellite markers to select core subsets that conserve the maximum genetic diversity. The highest genetic diversity was observed in the seed collections from natural populations of Yunnan, a region that is part ofM. balbisiana's centre of origin. The seeds from theex situfield collections were less genetically diverse, but contained unique variation with regards to the diversity in all seed collections. Seeds from feral populations displayed low genetic diversity. Core subsets that maximized genetic distance incorporated almost no seeds from theex situfield collections. In contrast, core subsets that maximized allelic richness contained seeds from theex situfield collections. We recommend the conservation and additional collection of seeds from natural populations, preferentially originating from the species' region of origin, and from multiple individuals in one population. We also suggest that the number of seeds used forex situseed bank regeneration must be much higher for the seed collections from natural populations.
Correlation of Remotely Sensed Surface Reflectance With Forcing Variables in Six Different Estuaries
Authors: Tao Jing , Hill Paul S.
Published: November 2019

This study examines the links between estuarine dynamics and longitudinal distributions of remotely sensed reflectance in estuaries. Reflectance at 655 nm from Landsat‐8 correlates with in situ measurements of surface turbidity. Images collected from 2013 to 2018 are used to investigate the spatial and temporal characteristics of reflectance distribution in six selected estuaries with different dynamics. The results show that the maximum magnitude (C
) and location (X
) of the reflectance are functions of two major forcing variables, the freshwater discharge and tidal stage. Salt wedge estuaries (i.e., the Fraser River, Connecticut River, and Columbia River estuary) are affected strongly by river discharge and are relatively less affected by tidal forcing. In salt wedge estuaries, the C
values along the river channel are correlated with river discharge, while the X
values generally are not. In partially mixed to strain‐induced periodic stratification (SIPS) estuaries (i.e., Delaware River) and SIPS‐to‐well‐mixed estuaries (i.e., Gironde estuary), the X
values are correlated with river discharge, but the C
values are not. SIPS‐to‐well‐mixed estuaries (i.e., Gironde estuary) and highly time‐dependent salt wedge to well‐mixed estuaries (i.e., Merrimack River estuary) are affected by tidal forcing. In these estuaries, the C
values are correlated with tidal stage. The C
values tend to be lower around high tide than low tide. Overall, the results demonstrate that remote sensing observations of ocean color can be utilized to infer subsurface estuarine processes. Satellite ocean color is a potential tool to monitor river discharge and to classify estuaries.
The Challenge Posed by Space Weather to High‐Voltage Electricity Flows: Evidence From Ontario, Canada, and New York State, USA
Authors: Forbes Kevin F. , St. Cyr O. C.
Published: November 2019

In this paper, we present evidence that geomagnetic activity has the potential to disrupt the electricity flows between Ontario, Canada, and New York State, USA. This conclusion is based on a modeling framework that makes use of weather data, electricity load data, measures of transmission “network effects,” proxies for geomagnetically induced currents and the expected level of power grid conditions. The model is estimated using hourly data throughout 1 May 2002 through 31 October 2003. The model is evaluated using out‐of‐sample hourly data over the period of 1 November to 9 December 2003. The out‐of‐sample predictions are more accurate when the forecasting equation reflects the estimated contribution of geomagnetic activity. The structural modeling results for the sample period indicate that the peak predicted effect of geomagnetic activity on the electricity flow was about 1,604 MWh in absolute value when the geomagnetically induced current proxy achieved a value of 363.2 nT/min. The analysis also indicates that the level of the geomagnetically induced electricity flow is highly dependent on ambient temperature and expected system conditions at the time of the geomagnetic storm. Moreover, geomagnetic activity is an important driver of the volatility in the electricity flows. The overall findings indicate that the scope of the challenge posed by space weather to the operations of the electric power system is likely understated.
Integration of Ki-67 index into AJCC 2018 staging provides additional prognostic information in breast tumours candidate for genomic profiling
Authors: Vissio Elena , Metovic Jasna , Osella-Abate Simona , Bertero Luca , Migliaretti Giuseppe , Borella Fulvio , Benedetto Chiara , Sapino Anna , Cassoni Paola , Castellano Isabella
Published: November 2019

Background

The Eighth edition of the American Joint Committee on Cancer (AJCC) staging system (2018) for breast cancer (BC) introduced the prognostic stage. Moreover, multigene assessment has been indicated to tailor staging in T1/T2/N0, ER-positive/HER2-negative BC. However, many National Health Systems do not provide reimbursement for routine testing. The aim of this study was to assess whether Ki67 proliferation index is prognostically relevant for patients’ candidacy for molecular testing.

Methods

A retrospective series of 686 ER+/HER2− BC were reclassified using AJCC 2018, and in the group of 521 patients for which AJCC 2018 recommends molecular evaluation, we assessed the prognostic efficacy of a prognostic stage enriched by Ki67 (Ki67-PS), considering Ki67 <20% an alternative to recurrence score <11 provided by Oncotype DX.

Results

We found that a group of BCs (35.6%, 58/163) assigned to IB stage by prognostic score were down classified to IA with Ki67-PS. The outcome of these 58 cases overlapped with that of lesions classified as stage IA using prognostic stage, showing a significantly better prognosis compared to IB tumours (HR = 2.79, p = 0.003).

Conclusions

These data suggest that Ki67 may be a reliable marker to enrich the 2018 AJCC prognostic score in BC patients’ candidacy for genomic profiling.
Acoustic enrichment can enhance fish community development on degraded coral reef habitat
Authors: Gordon Timothy A. C. , Radford Andrew N. , Davidson Isla K. , Barnes Kasey , McCloskey Kieran , Nedelec Sophie L. , Meekan Mark G. , McCormick Mark I. , Simpson Stephen D.
Published: November 2019

Coral reefs worldwide are increasingly damaged by anthropogenic stressors, necessitating novel approaches for their management. Maintaining healthy fish communities counteracts reef degradation, but degraded reefs smell and sound less attractive to settlement-stage fishes than their healthy states. Here, using a six-week field experiment, we demonstrate that playback of healthy reef sound can increase fish settlement and retention to degraded habitat. We compare fish community development on acoustically enriched coral-rubble patch reefs with acoustically unmanipulated controls. Acoustic enrichment enhances fish community development across all major trophic guilds, with a doubling in overall abundance and 50% greater species richness. If combined with active habitat restoration and effective conservation measures, rebuilding fish communities in this manner might accelerate ecosystem recovery at multiple spatial and temporal scales. Acoustic enrichment shows promise as a novel tool for the active management of degraded coral reefs.
Chemical unfolding of protein domains induces shape change in programmed protein hydrogels
Authors: Khoury Luai R. , Popa Ionel
Published: November 2019

Programmable behavior combined with tailored stiffness and tunable biomechanical response are key requirements for developing successful materials. However, these properties are still an elusive goal for protein-based biomaterials. Here, we use protein-polymer interactions to manipulate the stiffness of protein-based hydrogels made from bovine serum albumin (BSA) by using polyelectrolytes such as polyethyleneimine (PEI) and poly-L-lysine (PLL) at various concentrations. This approach confers protein-hydrogels with tunable wide-range stiffness, from ~10–64 kPa, without affecting the protein mechanics and nanostructure. We use the 6-fold increase in stiffness induced by PEI to program BSA hydrogels in various shapes. By utilizing the characteristic protein unfolding we can induce reversible shape-memory behavior of these composite materials using chemical denaturing solutions. The approach demonstrated here, based on protein engineering and polymer reinforcing, may enable the development and investigation of smart biomaterials and extend protein hydrogel capabilities beyond their conventional applications.
Homogeneous cobalt-catalyzed reductive amination for synthesis of functionalized primary amines
Authors: Murugesan Kathiravan , Wei Zhihong , Chandrashekhar Vishwas G. , Neumann Helfried , Spannenberg Anke , Jiao Haijun , Beller Matthias , Jagadeesh Rajenahally V.
Published: November 2019

The development of earth abundant 3d metal-based catalysts continues to be an important goal of chemical research. In particular, the design of base metal complexes for reductive amination to produce primary amines remains as challenging. Here, we report the combination of cobalt and linear-triphos (bis(2-diphenylphosphinoethyl)phenylphosphine) as the molecularly-defined non-noble metal catalyst for the synthesis of linear and branched benzylic, heterocyclic and aliphatic primary amines from carbonyl compounds, gaseous ammonia and hydrogen in good to excellent yields. Noteworthy, this cobalt catalyst exhibits high selectivity and as a result the -NH2 moiety is introduced in functionalized and structurally diverse molecules. An inner-sphere mechanism on the basis of the mono-cationic [triphos-CoH]+ complex as active catalyst is proposed and supported with density functional theory computation on the doublet state potential free energy surface and H2 metathesis is found as the rate-determining step.
Imaging and writing magnetic domains in the non-collinear antiferromagnet Mn3Sn
Authors: Reichlova Helena , Janda Tomas , Godinho Joao , Markou Anastasios , Kriegner Dominik , Schlitz Richard , Zelezny Jakub , Soban Zbynek , Bejarano Mauricio , Schultheiss Helmut , Nemec Petr , Jungwirth Tomas , Felser Claudia , Wunderlich Joerg , Goennenwein Sebastian T. B.
Published: November 2019

Non-collinear antiferromagnets are revealing many unexpected phenomena and they became crucial for the field of antiferromagnetic spintronics. To visualize and prepare a well-defined domain structure is of key importance. The spatial magnetic contrast, however, remains extraordinarily difficult to be observed experimentally. Here, we demonstrate a magnetic imaging technique based on a laser induced local thermal gradient combined with detection of the anomalous Nernst effect. We employ this method in one the most actively studied representatives of this class of materials—Mn3Sn. We demonstrate that the observed contrast is of magnetic origin. We further show an algorithm to prepare a well-defined domain pattern at room temperature based on heat assisted recording principle. Our study opens up a prospect to study spintronics phenomena in non-collinear antiferromagnets with spatial resolution.
Hydrogen bond guidance and aromatic stacking drive liquid-liquid phase separation of intrinsically disordered histidine-rich peptides
Authors: Gabryelczyk Bartosz , Cai Hao , Shi Xiangyan , Sun Yue , Swinkels Piet J. M. , Salentinig Stefan , Pervushin Konstantin , Miserez Ali
Published: November 2019

Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) is involved in both intracellular membraneless organelles and extracellular tissues. Despite growing understanding of LLPS, molecular-level mechanisms behind this process are still not fully established. Here, we use histidine-rich squid beak proteins (HBPs) as model IDPs to shed light on molecular interactions governing LLPS. We show that LLPS of HBPs is mediated though specific modular repeats. The morphology of separated phases (liquid-like versus hydrogels) correlates with the repeats’ hydrophobicity. Solution-state NMR indicates that LLPS is a multistep process initiated by deprotonation of histidine residues, followed by transient hydrogen bonding with tyrosine, and eventually by hydrophobic interactions. The microdroplets are stabilized by aromatic clustering of tyrosine residues exhibiting restricted molecular mobility in the nano-to-microsecond timescale according to solid-state NMR experiments. Our findings provide guidelines to rationally design pH-responsive peptides with LLPS ability for various applications, including bioinspired protocells and smart drug-delivery systems.
RETRACTED ARTICLE: Novel Therapeutic Approach Using Drug-loaded Adipose-derived Stem Cells for Pancreatic Cancer
Authors: Aoki Masahiko , Kakimoto Kazuki , Goto Masahiro , Higuchi Kazuhide
Published: November 2019

We developed anticancer drug-conjugated biodegradable polymer-nanoparticle-loaded adipose-derived stem cells (AdSCs) as a tool for biodrug delivery systems for cancer therapy. Pirarubicin was conjugated in polylactic/glycolic acid (PLGA) followed by formation of nanoparticles (NPs), which were loaded with human AdSCs and cocultured. The pirarubicin-conjugated PLGA NP-loaded AdSCs (PirNP-AdSCs) were overall viable within 48 h and exhibited significantly enhanced migration activity. We confirmed that pirarubicin was gradually released into the culture medium from PirNP-AdSCs, and the conditioned medium significantly inhibited the proliferation activity and induced the apoptosis of human pancreatic cancer cells (KP1N). PirNP-AdSCs also significantly induced tumor cell apoptosis in anex vivoculture system with KP1N-derived tumors, and there was increased invasion/migration of PirNP-AdSCs inside the tumor. Finally, we compared the therapeutic efficacy of the PirNP-AdSCs on KP1N-derived tumor growth with that of treatments of AdSCs alone, PirNPs alone or normal saline (control) in immunodeficient mice. Subcutaneous local administration of PirNP-AdSCs significantly inhibited tumor growth, inducing the apoptosis of tumor cells and vasculature compared with the other groups. The present therapeutic strategy might give rise to a novel cancer therapy minimizing the adverse side effects of anticancer drugs in patients who suffer from cancer.
Global optimization of metasurface designs using statistical learning methods
Authors: Elsawy Mahmoud M. R. , Lanteri Stéphane , Duvigneau Régis , Brière Gauthier , Mohamed Mohamed Sabry , Genevet Patrice
Published: November 2019

Optimization of the performance of flat optical components, also dubbed metasurfaces, is a crucial step towards their implementation in realistic optical systems. Yet, most of the design techniques, which rely on large parameter search to calculate the optical scattering response of elementary building blocks, do not account for near-field interactions that strongly influence the device performance. In this work, we exploit two advanced optimization techniques based on statistical learning and evolutionary strategies together with a fullwave high order Discontinuous Galerkin Time-Domain (DGTD) solver to optimize phase gradient metasurfaces. We first review the main features of these optimization techniques and then show that they can outperform most of the available designs proposed in the literature. Statistical learning is particularly interesting for optimizing complex problems containing several global minima/maxima. We then demonstrate optimal designs for GaN semiconductor phase gradient metasurfaces operating at visible wavelengths. Our numerical results reveal that rectangular and cylindrical nanopillar arrays can achieve more than respectively 88% and 85% of diffraction efficiency for TM polarization and both TM and TE polarization respectively, using only 150 fullwave simulations. To the best of our knowledge, this is the highest blazed diffraction efficiency reported so far at visible wavelength using such metasurface architectures.
Left Ventricular Deformation in Patients with Connective Tissue Disease: Evaluated by 3.0T Cardiac Magnetic Resonance Tissue Tracking
Authors: Wang Jin , Shi Ke , Xu Hua-yan , Zhao Qin , Liu Xi , Gao Yue , Yu Hong , Guo Ying-kun , Yang Zhi-gang
Published: November 2019

The aim of this study was to assess left ventricular (LV) myocardial strain in patients with connective tissue disease (CTD) and compare LV deformation between subgroups of idiopathic inflammatory myopathy (IIM) and non-IIM. Ninety-eight patients with CTD, comprising 56 with IIM and 42 with non-IIM, and 30 healthy subjects were enrolled and underwent 3.0T cardiac magnetic resonance imaging (MRI) scanning. The LV function and strain parameters were measured and assessed. Our result revealed that CTD patients had preserved LV ejection fraction (60.85%) and had significantly decreased global and regional peak strain (PS) in radial, circumferential, and longitudinal directions (all p < 0.05). IIM patients showed significantly reduced global longitudinal PS (GLPS) and longitudinal PS at apical slice, whereas all strain parameters decreased in non-IIM patients. Except GLPS and longitudinal PS at apical slice, all strain parameters in non-IIM patients were lower than those in IIM patients. By Pearson’s correlation analysis, the LV global radial and circumferential PS were correlated to N-terminal pro-brain natriuretic peptide level and LV ejection fraction in both IIM and non-IIM patients. This study indicated that CTD patients showed abnormal LV deformation despite with preserved LVEF. The impairment of LV deformation differed between IIM and non-IIM patients.
Initial radiographic tracheal ratio in predicting clinical outcomes in croup in children
Authors: Yang Wen-Chieh , Hsu Yu-Lung , Chen Chun-Yu , Peng Yi-Chin , Chen Jun-Nong , Fu Yun-Ching , Chang Yu-Jun , Lee En-Pei , Lin Mao-Jen , Wu Han-Ping
Published: November 2019

Croup is the leading infectious disease resulting in pediatric upper airway obstruction. Our purpose is to analyze diverse features of neck radiographs could be seen as an objective tool to predict outcomes in patients with croup. One hundred and ninety-two patients were prospectively recruited in pediatric emergency department with diagnosis of croup. The initial Westley score (WS), presence of steeple sign, extent of narrowing, and narrowing ratio on soft tissue neck radiographs were determined before and after treatments. The extent of frontal narrowing, extent of lateral narrowing, frontal ratio (FR), and lateral ratio (LR) were investigated to predict clinical outcomes in patients with croup. The extent of frontal/lateral narrowing and LR had significant correlation with outpatient status. Almost 71% of patients with FR values below 0.23 stayed in the hospital longer, whereas nearly 98% of patients with FR vales above 0.65 could be discharged. About 85% of patients with LR below 0.45 hospitalized longer. The LR and FR were significantly correlated with the severity and admission rate in croup. The LR > 0.6 and FR > 0.65 may indicate low risk in patients with croup, whereas the FR < 0.23 or LR < 0.45 may indicate the need of stay in hospital for further treatment and monitor.
Combined dietary supplementation of long chain inulin and Lactobacillus acidophilus W37 supports oral vaccination efficacy against Salmonella Typhimurium in piglets
Authors: Lépine Alexia F. P. , Konstanti Prokopis , Borewicz Klaudyna , Resink Jan-Willem , de Wit Nicole J. , Vos Paul de , Smidt Hauke , Mes Jurriaan J.
Published: November 2019

Routine use of antibiotics in livestock animals strongly contributed to the creation of multidrug-resistant Salmonella Typhimurium strains (STM). Vaccination is an alternative to the use of antibiotics but often suffers from low efficacy. The present study investigated whether long-chain inulin (lcITF) and Lactobacillus acidophilus W37 (LaW37) can support vaccination efficacy against STM and if the interventions influence possible gut microbiota changes. Piglets received daily supplementation until sacrifice. Animals were vaccinated on day 25 after birth, one day after weaning, and were challenged with STM on days 52–54. Dietary intervention with lcITF/LaW37 enhanced vaccination efficacy by 2-fold during challenge and resulted in higher relative abundance of Prevotellaceae and lower relative abundance of Lactobacillaceae in faeces. Although strongest microbial effects were observed post STM challenge on day 55, transient effects of the lcITF/LaW37 intervention were also detected on day 10 after birth, and post-weaning on day 30 where increased relative abundance of faecal lactobacilli was correlated with higher faecal consistency. LcITF treatment increased post-weaning feed efficiency and faecal consistency but did not support vaccination efficacy. Vaccination in immune-immature young animals can be enhanced with functional additives which can simultaneously promote health in an ingredient-dependent fashion.
The Usefulness of Lung Ultrasound for the Aetiological Diagnosis of Community-Acquired Pneumonia in Children
Authors: Berce Vojko , Tomazin Maja , Gorenjak Mario , Berce Tadej , Lovrenčič Barbara
Published: November 2019

The aetiology of community-acquired pneumonia (CAP) is not easy to establish. As lung ultrasound (LUS) has already proved to be an excellent diagnostic tool for CAP, we analysed its usefulness for discriminating between the aetiologically different types of CAP in children. We included 147 children hospitalized because of CAP. LUS was performed in all patients at admission, and follow-up LUS was performed in most patients. LUS-detected consolidations in viral CAP were significantly smaller, with a median diameter of 15 mm, compared to 20 mm in atypical bacterial CAP (p = 0.05) and 30 mm in bacterial CAP (p < 0.001). Multiple consolidations were detected in 65.4% of patients with viral CAP and in 17.3% of patients with bacterial CAP (p < 0.001). Bilateral consolidations were also more common in viral CAP than in bacterial CAP (51.9% vs. 8.0%, p < 0.001). At follow-up, a regression of consolidations was observed in 96.6% of patients with bacterial CAP and in 33.3% of patients with viral CAP (p < 0.001). We found LUS to be especially suitable for differentiating bacterial CAP from CAP due to other aetiologies. However, LUS must be interpreted in light of clinical and laboratory findings.
Probiotics ingestion prevents HDAC11-induced DEC205+ dendritic cell dysfunction in night shift nurses
Authors: Yang Hui , Yang Jing , Cheng Hui , Cao Huili , Tang Shan , Wang Qiaohong , Zhao Juan , Li Baohua , Ding Yongxia , Ma Chang
Published: November 2019

It is known that the day-night shift-rotation has a negative impact on the immune system. The underlying mechanism remains to be further investigated. Probiotics have regulatory effects on immune functions. This study aims to investigate the role of probiotic ingestion in preventing the DEC205+ dendritic cell (decDC) dysfunction in day-night shift-engaging nurses. In this study, blood samples were collected from day-night shift-rotating nurses who took or did not take yogurt (containing C. Butyricum) during the night shift (NS). decDC functions were evaluated with pertinent immunological approaches. We observed that the immune tolerogenic functions and interleukin (IL)-10 expression were impaired in decDCs of nurses after NS. HDAC11 was detected in decDCs that was markedly up regulated after NS. The HDAC11 levels were negatively correlated with the immune tolerogenic functions in decDCs. Ingestion of probiotic-containing yogurt during NS efficiently suppressed Bmal1 and HDAC11 levels as well as up regulated the immune regulatory functions in decDCs. In conclusion, NS has a negative impact on decDC immune tolerogenic functions, which can be prevented by ingesting probiotics-containing yogurt during NS.
Publisher Correction: In-hospital recurrence in a Chinese large cohort with acute ischemic stroke
Authors: Yu Fan , Liu Xiaolu , Yang Qiong , Fu Yu , Fan Dongsheng
Published: November 2019

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Negative Emissions Technologies
Authors: Daggash H. A. , Fajardy M. , Mac Dowell N.
Published: November 2019

The Paris Agreement signalled global consensus to keep average temperature rise “well below” 2 °C by the end of the century. Results from integrated assessment models have made it increasingly evident that negative emissions (removing CO2 from the atmosphere) are crucial to achieving this. Consequently, negative emissions technologies (NETs) have come to the forefront of mitigation discussions. NETs must however overcome challenges if they are to be realised at scale. Uncertainties around the large-scale biomass supply have fuelled a debate on whether negative emissions from bio-energy with carbon capture and storage (BECCS) are sustainably achievable, if at all. Reliable carbon accounting frameworks and policy incentives are needed to improve investment prospects. The direct extraction of CO2 from air, or direct air capture (DAC), has since been demonstrated as a source of negative emissions. The large energy and economic costs associated with extracting CO2 from air are proving prohibitive to achieving commercial viability of DAC technology. Without dedicated policy support for technological innovation, and further interdisciplinary research to constrain a variety of uncertainties, the world risks foregoing a portfolio of technologies that add much-needed flexibility in the mitigation toolbox. This chapter details the evidence for negative emissions, proposed means of achieving them and their barriers to commercial effectiveness.
Tuning the interpenetration of metal–organic frameworks through changing ligand functionality: effect on gas adsorption properties
Authors: Li Bin , Yan Qing-Qing , Xu Zhi-Qiang , Xu Ying-Bo , Yong Guo-Ping
Published: November 2019

Two interpenetrated MOFs are constructed with a 2-connected ligand, whereas one non-interpenetrated MOF is constructed by using a 3-connected ligand.
Correction: Highly efficient simultaneous adsorption of Cd(ii), Hg(ii) and As(iii) ions from aqueous solutions by modification of graphene oxide with 3-aminopyrazole: central composite design optimization
Authors: Alimohammady M. , Jahangiri M. , Kiani F. , Tahermansouri H.
Published: November 2019

Correction for ‘Highly efficient simultaneous adsorption of Cd(ii), Hg(ii) and As(iii) ions from aqueous solutions by modification of graphene oxide with 3-aminopyrazole: central composite design optimization’ by M. Alimohammady et al., New J. Chem., 2017, 41, 8905–8919.
Correction: Doping-free bandgap tuning in one-dimensional Magnéli-phase nanorods of Mo4O11
Authors: Van Pham Duy , Patil Ranjit A. , Lin Jin-Han , Lai Chien-Chih , Liou Yung , Ma Yuan-Ron
Published: November 2019

Correction for ‘Doping-free bandgap tuning in one-dimensional Magnéli-phase nanorods of Mo4O11’ by Duy Van Pham et al., Nanoscale, 2016, 8, 5559–5566.
Polyrotaxanes created by end-capping polypseudorotaxanes self-assembled from β-CDs with distal azide terminated PHEMA using propargylamine monosubstituted β-CDs
Authors: Gao Ming , Lu Hang , Song Rong-hao , Ye Lin , Zhang Ai-ying , Feng Zeng-guo
Published: November 2019

When a distal azide terminated PHEMA was allowed to self-assemble with varying amounts of β-CDs in water, followed by in situ reaction with PA-β-CDs via the CuAAC, linear polyrotaxanes (PRs) and a mixture of linear and hyperbranched PRs were obtained.
Correction: Synthesis of DNA-guided silver nanoparticles on a graphene oxide surface: enhancing the antibacterial effect and the wound healing activity
Authors: Tong Chunyi , Zou Wei , Ning Weimin , Fan Jialong , Li Li , Liu Bin , Liu Xuanming
Published: November 2019

Correction for ‘Synthesis of DNA-guided silver nanoparticles on a graphene oxide surface: enhancing the antibacterial effect and the wound healing activity’ by Chunyi Tong et al., RSC Adv., 2018, 8, 28238–28248.
The influence of DNA methylation on monoallelic expression
Authors: da Rocha Simão Teixeira , Gendrel Anne-Valerie
Published: November 2019

Monoallelic gene expression occurs in diploid cells when only one of the two alleles of a gene is active. There are three main classes of genes that display monoallelic expression in mammalian genomes: (1) imprinted genes that are monoallelically expressed in a parent-of-origin dependent manner; (2) X-linked genes that undergo random X-chromosome inactivation in female cells; (3) random monoallelically expressed single and clustered genes located on autosomes. The heritability of monoallelic expression patterns during cell divisions implies that epigenetic mechanisms are involved in the cellular memory of these expression states. Among these, methylation of CpG sites on DNA is one of the best described modification to explain somatic inheritance. Here, we discuss the relevance of DNA methylation for the establishment and maintenance of monoallelic expression patterns among these three groups of genes, and how this is intrinsically linked to development and cellular states.
The role and mechanisms of DNA methylation in the oocyte
Authors: Sendžikaitė Gintarė , Kelsey Gavin
Published: November 2019

Epigenetic information in the mammalian oocyte has the potential to be transmitted to the next generation and influence gene expression; this occurs naturally in the case of imprinted genes. Therefore, it is important to understand how epigenetic information is patterned during oocyte development and growth. Here, we review the current state of knowledge of de novo DNA methylation mechanisms in the oocyte: how a distinctive gene-body methylation pattern is created, and the extent to which the DNA methylation machinery reads chromatin states. Recent epigenomic studies building on advances in ultra-low input chromatin profiling methods, coupled with genetic studies, have started to allow a detailed interrogation of the interplay between DNA methylation establishment and chromatin states; however, a full mechanistic description awaits.
Adaptive fractional‐order control of power system frequency in the presence of wind turbine
Authors: Kazemi Mohammad Verij , Gholamian S. Asghar , Sadati Jalil
Published: November 2019

Inertial and droop control are common methods for improving grid frequency control. Using the first‐order derivative of the frequency in the inertial control loop only investigates the rate of frequency variation, while other useful information is not taken into consideration. Accordingly, in this study, the application of a fractional‐order derivative (between 1 and 2) in the inertial control loop is proposed to have more useful frequency‐based information. To achieve this goal, firstly continued fraction approximations and secondly, the discretization is adopted by using the Tustin Method with Prewarping. Inertia loop and droop loop gain have a significant impact on the operation of the wind turbines and the power system frequency control. Therefore, in this paper, a novel method for the adaptive adjusting of droop and inertia control loops gains in DFIG is proposed. To utilize more frequency error information, fractional‐order adaptive law is proposed to update the loop gains and the inertia control loop. In order to have a robust system, which is permanently stable for every fractional order (FO), is used parameter space method. Simulation results demonstrate the proper performance of the FO‐based adaptive approach to increase the frequency nadir (FN) and decrease the frequency variations.
Lapping flat surfaces with forced dosing of abrasive suspension
Authors: Gniot Maciej , Barylski Adam
Published: November 2019

The issues concerning the finishing of flat ceramic seals are presented in the paper. The treatment requirements demanded from the elements of that type cause, that necessary is application of grinding-in in the technological process. Such a precise abrasive treatment of flat surfaces of that type, requires the use of an appropriate suspended matter or abrasive paste. Many factors connected with metal grinding-in shield, components of abrasive suspended matter and the treatment’s technological conditions, have an impact on the treatment’s result. The manner and intensity of the suspended matter’s proportioning in the grinding-in are, are also of decisive nature. A standard, free manner of proportioning, in a continuous manner most often dipping or dropping, results in big losses of abrasive material. A part of abrasive micro-grains is quickly removed from the operating grinding-in shield by the rotating rings leading separators with treated elements and does not take part at all in machine cutting. It considerably increases the tool costs and has an unfavourable impact on the natural environment. Implementation of the forced abrasive suspended matter’s proportioning at the time of the machine grinding-in, considerably reduces these losses.
Research of characteristics of environmental energy carriers by simulation of operating load in laboratory conditions
Authors: Janouskova Romana , Kaszkowiak Jerzy , Halenar Marek , Zachar Martin , Nosian Jozef
Published: November 2019

The focus of this sceintific article is a laboratory research on the qualities of environmental energy carriers by simulating the operational load, focusing on changes of physico-chemical qualities of ecological hydraulic and transmission fluid used in agricultural tractors. In laboratory setting by using a simulator, it was possible to simulate different operational load and also track changes in qualities of hydraulic fluid by changing the flow in precise intervals. The hydraulic-transmission fluid used in the laboratory setting was the MOL Farm NH Ultra.
Impact of changes in the fuel injection controller settings on the power and torque performance depending on the engine speed
Authors: Markiewicz Marietta , Dluhunovych Natalia
Published: November 2019

The internal combustion engine is the powerhouse of motor vehicles. The basic fuel used for self-ignition engine powering is diesel oil. The efficiency of an internal combustion engine depends on many factors and is defined by such parameters as power output, torque, and the engine rotational speed. The engine performance parameters can be improved by modification of the manufacturer’s computer software that controls the engine operation. The study presents results of tests of a drive unit involving adjusting the fuel injection controller settings. The modifications involved increasing the fuel dose and the air charge pressure. Tests were carried out on a load bearing chassis dynamometer. The research object was a self-ignition engine with 109 KM power and Common Rail injection system. Power and torque measurements were carried out for the engine rotational speed range up to 4000 rev/min. It was found that modifications of the manufacturer’s engine computer software contribute to power and torque increase for all the rotational speeds.
Diagnostics of Corrosion Protection Potential for Electric Water Heaters
Authors: Martynyuk Valeriy , Liss Michał , Wilczarska Joanna
Published: November 2019

The paper represents the mathematical model for diagnostics of the corrosion protection potential for the electric water heaters (EWH). The research objectives are the problem of determining the EWH corrosion protection technical condition during its operation. The EWH corrosion protection diagnostics is based on the mathematical model of the corrosion protection potential for EWH. The model is based on the nonlinear equivalent circuit which is modelling the nonlinear impedance of the corrosion cathodic protection. In the development of the mathematical model the authors carried out experimental measurements of the impedance for the EWH body fragment. The obtained experimental results show that mathematical model includes the fractional integrating elements. By using of the experimental results the expressions of the impedance, the impulse response is obtained. The methodological approach to increasing the reliability of the EWH corrosion protection diagnostics has been proposed, in terms of the multi-parameter diagnostics, by applying the EWH corrosion protection impedance model.
Method of assessment of the transport system functioning with the application of the simulation model of the operating process
Authors: Migawa Klaudiusz , Sołtysiak Agnieszka , Czyżewska Magda
Published: November 2019

In the article, there is presented the description of the algorithm of the operating process of the simulation model characteristics’ determination realized in the transport system. The simulation model of the means of transport’s operating process has been developed based on the that process’s mathematical model (semi-Markov model). Due of the assumed principles, the constructed model can be applied for the purposes of assessment and control of the operating process because of criterion of different types. Analysis of performance’s assessment of the operating means of transport is one of the ways of the possibilities of correct realization of the assigned transportation tasks in the transport systems. The simulation model of the operating process presented in the work, makes it possible to assess performance of the transport system’s operation from the point of view of the selected assessment criteria: availability of the means of transport and the unit income generated in the process’s modelling conditions. Based on the results of the tests conducted in the real system of the means of transport operating system, the model’s input data have been developed and simulation experiments have been conducted. As an effect, there have been determined the exemplary values of the analyzed characteristics of the transport system’s operation performance analyses.
7e Journées Protection Cathodique et Revêtements Associés
Authors: Fontaine Sylvain
Published: November 2019

Le CEFRACOR organise, du 9 au 11 juin 2020, les 7e Journées Protection Cathodique et Revêtements Associés, destinées
à rassembler toutes les personnes intéressées par ces techniques, qu’elles soient expertes, spécialistes ou encore peu
familières de ces domaines. Elles s’adressent aux donneurs d’ordre et utilisateurs comme aux concepteurs, fournisseurs,
sociétés de service ou encore aux administrations, laboratoires, universités et centres de recherche. Cet évènement
est enregistré par la Fédération européenne de corrosion (EFC) sous la désignation EFC Event n° 455.
L’intelligence artificielle au service de l’orthodontie : l’exemple de Dental Monitoring
Authors: Costi Arnaud
Published: November 2019

En médecine, le recours à l’intelligence artificielle est en plein essor, en particulier dans le domaine de l’analyse d’images. L’orthodontie n’échappe pas à cette révolution technologique sans précédent. A travers l’exemple du logiciel Dental Monitoring, nous comprendrons à quel point l’intelligence artificielle constitue une aide précieuse, que ce soit pour le diagnostic, le pronostic ou la thérapeutique orthodontique.
Recherche en Orthopédie Dento-Faciale : les erreurs statistiques à éviter
Authors: Oueiss Arlette , Faure Jacques
Published: November 2019

L’Evidence Based Medecine (EBM) a contribué à obliger les chercheurs à une exigence de rigueur accrue. Les Revues Scientifiques ont participé à cette évolution par une plus grande sévérité dans la sélection des articles.

Le nombre des articles refusés (75%) pour certaines publications) et la dénonciation fréquente, parmi les raisons de rejet, des failles dans le traitement statistique, incitent à la réflexion développée ici, qui aborde successivement :

Les erreurs liées aux premières étapes du protocole (sélection des échantillons, choix des VA…).

Les déficits concernant les statistiques descriptives et la mise en œuvre des statistiques élémentaires au niveau d’un pré-protocole…

Enfin le manque de communication avec le statisticien aguerri en charge des statistiques complexes et/ou spécifiques qui conduisent à la compréhension intime des relations internes (inter-paramètres) au sein du fichier-source.

Les auteurs conseillent aux jeunes chercheurs en charge d’une base de données importante d’être vigilants à trois moments :

Considérez attentivement les mesures à réaliser, les échantillons à réunir, les paramètres à utiliser, quels résultats vous attendez et quelle analyse vous envisagez.

Pensez à un pré-protocole sur quelques patients, avec mise en œuvre systématiques des outils usuels (accessibles sur tout logiciel et même sur un tableur) et examen attentif des statistiques descriptives et des rapprochements élémentaires (cœfficient de corrélation par exemple).

Abordez des Statistiques complexes avec l’aide d’un statisticien « chevronné ».
Atemblockaden „ohne Grund“?
Authors: Jahn Claus
Published: November 2019

Schwindel und Übelkeit bei tiefer Einatmung – mit diesem ungewöhnlichen Beschwerdebild durchlief Frau A. über Monate erfolglos Praxen und Therapien. Nachdem sich eine traumatische Blockierung der Atemexkursion zeigte, wurde die Patientin durch eine manualtherapeutische Mobilisierung von Zwerchfell und Fascia endothoracica in Verbindung mit Neuraltherapie komplett beschwerdefrei. Der Beitrag beschreibt auch die umfangreiche Diagnostik und Therapie im Vorfeld sowie mögliche weitere Therapieansätze hinsichtlich der später widerlegten Verdachtsdiagnosen: spastische Bronchitis, Angst und Herzstörungen.
Secondary Management of Midface Fractures
Authors: Aman Hessah , Shokri Tom , Reddy Likith V. , Ducic Yadranko
Published: November 2019

Secondary reconstruction of posttraumatic facial deformities has been consistently described as one of the most challenging procedures performed. Ideal primary reconstruction cannot always be achieved, and often it is complicated by severe comminution or inadequate surgical management. It also can arise because of a lack of definitive surgical repair or excessive delay of initial treatment. Complications leading to secondary deformities can occur even when craniofacial injuries are treated by experienced surgeons. Following proper surgical principles, meticulous perioperative planning, and anticipation of potential functional and aesthetic sequelae limit many of those complications. Herein, we discuss secondary procedures in traumatic midface injuries.
Aqueous Photon Upconversion by Anionic Acceptors Self-Assembled on Cationic Bilayer Membranes with a Long Triplet Lifetime
Authors: Asthana Deepak , Hisamitsu Shota , Morikawa Masa-aki , Duan Pengfei , Nakashima Takuya , Kawai Tsuyoshi , Yanai Nobuhiro , Kimizuka Nobuo
Published: November 2019

Anionic 9,10-diphenylanthracene chromophores electrostatically bound to cationic, chiral bilayer membranes show ordered self-assembly in water. The integrity of the chromophore-accumulated aqueous bilayer membranes is ensured by multiple hydrogen-bond networks introduced in the bilayer, which allowed adaptive accommodation of the guest chromophores at the inner surface of the bilayer while maintaining their cohesive interactions. The regular chromophore alignment in the aqueous assembly is confirmed by differential scanning calorimetry, circular dichroism, and circularly polarized luminescence spectra. Excitonic migration of triplet energy occurs among the chromophores densely organized at the inner surface of the bilayer, which lead to triplet–triplet annihilation-based photon upconversion (TTA-UC). This acceptor-bilayer self-assemblies show a notably long triplet lifetime of 8.0 ms, which allows TTA-UC at sufficiently low excitation light intensity. These results demonstrate the usefulness of the simple electrostatic accumulation approach for TTA-UC chromophores where the suitable molecular design of the TTA-UC chromophore-integrated bilayer membranes plays a key role.
2.5 Organocatalyst/Biocatalyst Dual Catalysis
Authors: Yamashita Y. , Gröger H.
Published: November 2019

The combination of catalysts from the fields of organocatalysis and biocatalysis toward chemoenzymatic one-pot syntheses is an attractive concept for enabling efficient enantioselective synthetic processes for chiral building blocks without the need for isolation of intermediates, thus avoiding time-consuming as well as waste-producing work-up steps.
Photosensitivity of composite erbium-doped phosphorosilicate optical fibres to 193-nm laser radiation
Authors: Rybaltovsky A.A. , Vasil’ev S.A. , Butov O.V. , Egorova O.N. , Zhuravlev S.G. , Semjonov S.L. , Galagan B.I. , Sverchkov S.E. , Denker B.I.
Published: November 2019

Results of studying photoinduced changes of a refractive index in the core of a composite erbium-doped phosphorosilicate optical fibre under pulsed UV irradiation at a wavelength of 193 nm and the annealing of these changes are presented and analysed. It is shown that the preliminary saturation of a composite optical fibre by molecular hydrogen substantially increases the photosensitivity. Analysis of thermal anneal kinetics revealed fundamental differences in the photosensitivity mechanisms between the optical fibres saturated with hydrogen and not subjected to hydrogen treatment. Initial and photoinduced absorption spectra of the phosphorosilicate glass are investigated. It is found that in the UV range, the induced absorption is mainly determined by a contribution from the intense absorption band of photoinduced phosphorus electron centres PO2 with a maximum at 4.7 eV (λ = 260 nm).
Single-frequency fibre laser with a cavity formed by Bragg gratings written in the core of an active composite fibre using KrF laser radiation (248 nm)
Authors: Egorova O.N. , Medvedkov O.I. , Seregin E.S. , Vasil’ev S.A. , Sverchkov S.E. , Galagan B.I. , Denker B.I. , Danielyan G.L. , Pustovoi V.I. , Semjonov S.L.
Published: November 2019

The possibility of producing a single-frequency fibre laser using a new type of fibre made by sintering phosphate glass in a silica glass tube (composite fibre) is demonstrated. In a fibre of this type, photosensitivity to laser radiation with a wavelength of 248 nm is detected. A fibre laser cavity is fabricated by writing fibre Bragg gratings directly in the core of the composite optical fibre activated by erbium ions. Stable single-frequency linearly polarised lasing regime is obtained at a wavelength of 1559.5 nm with a maximum output power of ∼3 mW.
Dynamics and quantum fluctuations of light in nonstationary operation modes of a Raman fibre amplifier
Authors: Mel’nikov L.A. , Mazhirina Yu.A.
Published: November 2019

We report the results of numerical simulation of the radiation dynamics in a Raman fibre amplifier taking into account quantum fluctuations of the pump fields and Stokes waves. The simulation relies on an approach based on solutions of the transport equations for complex amplitudes and on the ‘backward’ propagation method for operators describing quantum fluctuations. It is shown that there exists an optimal Raman amplifier length corresponding to the minimum level of fluctuations of the amplified Stokes pulse.