bluuebunny/crossref_metadata_2025 huggingface dataset:
Immunological phenotypes of intolerance of dental materials
Authors: Karpuk I.
Published: September 2021

The purpose of work was the research of the immune status and allocation of immunologic phenotypes at patients with the intolerance of stomatologic materials (ISM). Examination 91 patients aged from 46 up to 65 years, with complaints to ISM is conducted. As a result of a research of the T-cellular link of system of immunity at patients with an intolerance of stomatologic materials, but without the taped hypersensitivity to their components, taped the following patterns: statistically reliable (р<0,05) depression of the CD3+ levels of the T-general (47,9±3,7 at norm in control group – 66,2±4,5) and CD4+ of T-helpers (30,6±2,8 at norm of donors 38,2±3,2). It is noted reliable (р<0,05) depression of IRI (1,49±0,32 at norm of donors 1,76±0,36). At patients with complaints to an intolerance of stomatologic materials and the taped hypersensitivity, by results of application assays and reaction of allergenindutsirovanny damage of leucocytes the immune status was characterized reliable (р<0,05) by rising of quantity of the lymphocytes carrying CD25+ markers for 36,2% in comparison with those in control group (р<0,05). The augmentation of IRI (2,33±0,54) in comparison with control group (1,76±0,36) (р<0,05), generally at the expense of the increased CD4+ level of T-helpers and relative depression the maintenance of CD8+ of T lymphocytes to 18,3±3,6% is established (patients of control group have 21,7±3,09%). At that group depression of the IgA level (р<0,05) in blood serum to 1,36±0,12 g/l and in oral liqid to 0,042±0,0023 g/l is taped, and patients of control group have 2,57±0,06 g/l and 0,11±0,04 g/l respectively. The lowered activity of neutrocytes by results of spontaneous (8,4±3,5%) and induced (41,4±5,3%) is established to test NST at patients with ISM without hypersensitivity to dental alloys that authentically (р<0,05) differed with similar indicators of patients with ISM and the taped hypersensitivity to components of dental alloys. Indicators of the increased metabolic activity of neutrophils at patients with complaints to NSM and the taped hypersensitivity to dental alloys and their components defined in the NST-test correlated with: levels IgA of stomatic liquid (r=-0,55; р<0,05); quantity of dentoprosthetic units (r=0,72; р<0,05); terms of use of dentoprosthetic designs (r=0,47; р<0,05). The data obtained by us show two immunologic phenotypes of ISM: one with a hypersensitivity to them, the second with its absence. At both phenotypes signs of deficiency of local and general immunity which differed at these phenotypes are taped.
The impact of fetal load of biologically active substances of Hirudo verbana saline extract antigens on the morphometric and hematologic parameters of rats in the early stages of post-embryonic development
Authors: Aminov R. , Frolov A. , Fedotov Y.
Published: September 2021

The female rats of wild type 2 weeks before and 2 weeks after mating were administered intraperitoneally medicinal leech saline extract antigens (4 injection). Studied females after feeding the offspring and the offspring itself in dynamics at 1, 15, 30, 60 days. All animals were decapitated under anesthesia after measuring morphometric parameters of the body. Then we did the autopsy animals and studied morphometric parameters of immunogenic organs (spleen and thymus), laboratory parameters: total white blood cells count, red blood cells count, hemoglobin, color index, leukocyte formula. As a result of our investigations was found an immunostimulatory effect of antigens from saline extract of the medicinal leech on morphometric parameters of the body and major immunogenic organs of rats. Under the influence of medical leeches’ antigens from the first day increased the number of white blood cells, increased the number of red blood cells, increased hemoglobin, color index was in the normal range. Changes of morphological and hematological parameters indicate the immune-stimulating impact of medical leeches’ antigens on leucopoiesis, erythropoiesis and morphogenesis.
On the role of galectin-3 and interleukin-6 in immune responses of rosacea patients
Authors: Aripova M. , Zima A. , Vasil’eva O. , Hardikova S.
Published: September 2021

Aim. Determining the level of galectin-3, IL-6 in the blood serum of patients with rosacea and rosacea in combination with chronic opisthorchiasis. Subjects and methods. In the blood serum of 80 rosacea patients, 64 patients with rosacea, combined with chronic opisthorchiasis and 20 healthy donors were studied concentrations of galectin 3, IL-6 by ELISA. Results. The concentration of galectin 3, IL-6 was significantly elevated in patients with rosacea, rosacea, combined with chronic opisthorchiasis as compared with the healthy controls. The positive correlation between the severity of clinical manifestations of rosacea and the level of galectin 3 (r = 0,72), IL-6 (r = 0,64) in the two groups. Conclusion. The results indicate an imbalance content (galectin-3; IL-6) in serum of patients with rosacea, which can be seen as further evidence of the inferiority of the immune response in rosacea.
Flexibility of Dense 3D Data Capture
Authors: Attenni Martina , Griffo Marika , Inglese Carlo , Ippolito Alfonso , Lo Eric , Rissolo Dominique
Published: September 2021

The knowledge and study of built heritage is now deeply connected to methodologies associated with the capture of surface details via the production of point-data. These methodologies enable researchers to gather a wider range of information, which is increasingly more connected to technological advances. Such approaches influence the management of data, and these data are often redundant due to the ways in which they are captured. Massive data capture does not include preliminary selection based on metric, geometric, and material features of the object. A multi-scalar approach, in which the criteria for data capture depends on the goals of the survey, is needed to optimize the relationship between information and the scale of the models to be built. This case study involving a selection of fountains in Rome aims to apply these principles to urban contexts defined by a strong spatial connection between architectural and sculptural elements. Survey can express this distinctiveness through complex, dynamic, and effective digital models.
Making Environmental Education Accessible for All Students: Inclusion of students with emotional and behavioral disabilities
Authors:   Notre Dame of Maryland University, Dupuis Juliann , Jacobs Dawn ,   Notre Dame of Maryland University
Published: September 2021

One of the most difficult tasks of an educator is engaging students in rigorous learning opportunities. A greater challenge is finding ways in which environmental education can be accessible to all students, especially those with emotional and behavioral disabilities. This article and lesson provides best practices for engaging students with high incidence disabilities in environmental concepts through varied representations and expressions of content. In addition, teaching collaborative protocols to fully engage students with social skills challenges within the local environment are discussed. The instructional approaches are aligned to increasing academic discourse, building positive peer-peer relationships, and observation using multiple modalities.
Making Scientific and Technical Materials Pervasively Accessible
Authors:   Educational Testing Service, White Jason J.G.
Published: September 2021

In this paper, the question is explored of what policies, standards and practices are desirable to ensure that hardware, software and publications in the sciences and associated disciplines are created from the outset to be accessible to people with disabilities. Insight into this question can be obtained by considering the unique accessibility challenges that these materials pose, including complexities of notation, language, and graphical representation. Having analyzed what sets this problem apart from broader issues of accessibility, the advantages and limitations of current international standards are reviewed, and contemporary developments in standards and policies are considered from a strategic perspective. These developments include the establishment of accessibility requirements for e-books and e-readers under the European Accessibility Act, the potential role of process-oriented accessibility standards such as ISO/IEC 30071-1:2019, and opportunities for enhancing the standards applicable to scientific materials via future revisions of the World Wide Web Consortium’s Web Content Accessibility Guidelines (WCAG). The accessibility of scientific and technical content is ultimately supported by several interrelated human rights recognized in international disability rights law, which constitute a foundation for further evaluation and development of policies. It is argued that attaining pervasive accessibility in scientific and technical fields requires an unprecedented level of commitment and collaboration among educators, scientists, content and software producers, regulators, and people with disabilities.
Build Your Own Body Mod: Empowerment through Prototyping and Design
Authors:   Make Just Right, Arreola Anaiss , Ganim Katherine R. ,   Born Just Right
Published: September 2021

When you don’t have a hand, what could you have instead? This article introduces the impact of inviting youth with disabilities to learn tools and technology to design their own solutions and advocate for their own future. This approach to programming is rooted in a mindset of designing WITH, not FOR. Not only are design outcomes improved when users are incorporated into the process, but this approach has been shown to improve confidence in creating one’s own solutions. These programs include hands-on “design-your-own-body-mod” workshops, as well as a budding inclusive design consultancy led by youth with disabilities. Through this programming, youth not only develop technical and cutting edge skills, confidence, and meaningful solutions, but they also develop a clearer understanding of design and engineering career paths and establish their own network of Science, Technology, Engineering, Arts, and Mathematics (STEAM) professionals.
Breathing and temperature detection using thermal images in infants
Authors: Rodríguez-Cediel Ana Carolina , Gómez-Vargas Ernesto , Perdomo-Charry Oscar Julian
Published: September 2021

Sudden Infant Death Syndrome (SIDS) is one of the leading causes of death in children under one year of age. SIDS is defined as the death of a child under one year of age, without apparent symptoms or causes during sleep that lead to his death. Therefore, monitoring of childhood sleep has become vital for parents, health care providers and health educators during the perinatal period. Temperature and respiration are the parameters most used during neonatal and postnatal consultations as an indicator of events related to the SIDS. This document proposes a method of non-invasive detection of temperature and breathing, based on the automatic detection of areas of the forehead, nose and mouth of the infant, calculating statistical measures and pixel-temperature conversion of thermal images. The proposed method used 7.189 thermal images of 6 infants during sleep, obtaining a general accuracy of 88,26% in temperature and breathing detection into three different classes.
Matrix of coefficients for the differential equation of Chauchy-Euler
Authors: Castellanos-Moreno Fabio Hernando , Pantoja-Benavides Jaime Francisco
Published: September 2021

In this article application and advance is given to the method that allows to find in a simple way the constant coefficients that are required in the solution of a differential equation with the structure of Cauchy-Euler, presented and made known in [1]. Here we will see the construction form of the characteristic polynomials, using the aforementioned method as a basis; with a series of equations, matrices and novel methods to solve this type of ODEs and, above all, very practical for the equation of a much higher order. The idea is to present a structure or methodology in matrix form that allows to solve in a practical way differential equation of higher order with Cauchy-Euler structure.
EXPRO: exoskeleton for rehabilitation of upper limb
Authors: Garnica-Molina Javier Fernando , Bustos-Ramírez Juan Nicolás , Parrado-Agudelo Jessica Zuleima , Casallas-Contreras Cristian Mauricio , Méndez-Moreno Luis Miguel
Published: September 2021

In the upper limb rehabilitation field, assisting to various patients per day, in different kinds of therapies is an exhausting task which can be achieved in a semiautomated or automated manner.  The ExPro is an exoskeleton of 3 degrees of freedom designed and created to support rehabilitation treatments for patients with little or no mobility in their arms. The device consists in a machine able to move forearm and wrist according to prone-supination, ulnar and radial deflection and flex-extension of wrist movements. The proposed prototype was designed to assist therapists in the first step of rehabilitation treatments, thus, passive therapies. Each mechanical component was designed in the Inventor 3D software and printed on PLA materials (polylactic acid). The controlling step is a Raspberry Pi 3 that receives information, interprets and connects power, and control PCBs. The design and calculations were tasted with the finite elements tool of inventor software. The work result presents an exoskeleton prototype easy to operate and transport, safe for the patient and able to carry out several preprogramed movements.
Integration of hardware and web artefacts in embedded systems
Authors: Pardo-Cadena Duván Arley , Camargo-López Julián Rolando , Perdomo-Charry Cesar Andrey
Published: September 2021

This paper is a guide for the realization of integration processes between Web artifacts and the Hardware that supports them in Embedded Systems oriented to the internet of things. This suggested method is based on tests and hardware and software architecture design that contemplates the support of Web transactions taking into account the limitations of an Embedded System. The result of the study is a guide for working groups with a structured systematic and coherent orientation of process of integration between software and hardware, aimed to Embedded Systems that interact on the Web.
Unsustainable measures? Assessing global competence in PISA 2018
Authors: Chandir Harsha , Gorur Radhika
Published: September 2021

In the context of rising fundamentalism, urgent threats to the environment, and the persistence of poverty and deep inequities in the world, 193 nations have pledged to work towards the Sustainable Development Goals (SDGs) crafted by UNESCO in 2015. Education is seen as key to attaining all the other SDGs. Within the ‘education goal’ (Goal #4), there is an explicit target, SDG 4.7, which focuses on ‘sustainable development and global citizenship’. Nations are expected to incorporate a focus on SDG 4.7 into their curricula, policies, teacher education programs, and student assessment. PISA has now developed an assessment of ‘global competence,’ which is presented as a way to assess SDG 4.7. Through this assessment, it seeks to inform policy, curricula, and pedagogies and catalogue ‘best practices’ for developing students’ ‘global competence’. Given this ambition and the centrality of ‘sustainable development and global citizenship’ within the globally endorsed SDGs, it is important to analyze the extent to which the PISA assessment of global competence is usefully able to inform policy and practice and contribute to fulfilling SDG 4.7. We build upon the work of other scholars examining this question, taking a material-semiotic approach inspired by Science and Technology Studies. Empirically, our study is based on documentary analysis, interviews, and ‘survey encounters’ in which we administered a curated part of the assessment to 15-year-olds and followed this exercise with interviews. We explore how the hard-won stability gained around the notion of ‘global competence’ through its inscription into the standardized survey instruments is again threatened when the survey instrument encounters diverse 15-year-olds. The survey encounters provide an opportunity to ‘test the test’, and we conclude that the PISA test of global competence is not as yet in a position to provide useful direction to policy or practice in the promotion of SDG 4.7.
David Vopřada, Tertulián: O modlitbě
Authors: Sládek Karel
Published: September 2021

Book review on David Vopřada, Tertulián: O modlitbě, Praha: Krystal OP, 2020, 107 s., ISBN: 978-80-7575-076-1.
Sacramental Realism of Chesterton and Lewis
Authors: Hrabovecký Pavol
Published: September 2021

The aim of this study is to present G. K. Chesterton’s and C. S. Lewis’s understanding of sacramental realism and its possible adoption in pre-evangelisation. It is demonstrated that G. K. Chesterton’s works influenced C.S Lewis’s conversion, his Christian literary thinking, and his apologetics. Both Chesterton and Lewis offered sacramental perceptions of the world, available through the baptism of imagination. In their works, imagination helps reason to expand and recognise the supernatural in the natural. Therefore, imagination is an essential part of their apologetics of Christianity, which still appeals to contemporary man. In this way, new imaginative apologetics can serve as a suitable preparation for the proclamation of the Gospel today.
Úspěch v české frazeologii
Authors: TÁBORSKÁ Karolína
Published: September 2021

Příspěvek je věnován problematice jazykového obrazu světa konceptu ÚSPĚCH. Jde o prvotní, dílčí výzkum zaměřený na systémová data v rámci disertační práce, která se věnuje pojmu ÚSPĚCH v jazykovém obrazu světa českých žáků. Předmětem je kognitivně-lingvistická analýza frazeologického materiálu s cílem udělat si počáteční představu o konceptualizaci tohoto pojmu v českém jazykovém prostředí. Postupně odhalujeme představová schémata a konceptuální metafory, které se s tímto pojmem pojí.
Sentence and the compound sentencein Julius Zeyer’s epic poetry and prose
Authors: SCHACHERL Martin
Published: September 2021

The aim of this paper is to explore the use of the sentence and the compound sentence in the literary works of the Czech poet Julius Zeyer (1841–1901). Specifically, we intend to make a quantitative identification of congruencies and parallels, typical of the syntactic structure of Zeyer’s epic poetry and prose, as evidenced by a detailed analysis of particular stylistic devices used in the selected representative texts. The aim of this paper is to corroborate, or possibly to exclude, the impact of the selected narrative means of expression on the stylistic and compositional variances of the text, which is facilitated by paying full attention to one aspect of Zeyer’s authorial style, namely, the quantitative variation of sentences and compound sentences.
Diskurzní konektor »což« v neformálních mluvených rozhovorech
Authors: BÍLKOVÁ Jana
Published: September 2021

Článek shrnuje výsledky korpusového výzkumu zaměřeného na uplatnění výrazu což v neformální mluvené komunikaci. Jeho dominantní funkcí jak v psaných, tak v mluvených textech je funkce navazovacího relativa. V neformálních mluvených rozhovorech však ještě výrazněji než v textech psaných dominuje základní tvar což, ostatní pádové tvary (čehož, čemuž, čemž, čímž) jsou jen okazionální. Vysoká frekvence výrazu což v neformální mluvené komunikaci je dána mimo jiné jeho uplatněním ve funkci diskurzního konektoru, kterým mluvčí vyjadřuje návaznost repliky na repliku předchozí, který však nemá větněčlenskou platnost a neobsazuje v navazující výpovědi žádnou strukturní pozici.
Kam spěje vývoj nejen flexe proprií?
Authors: ČECHOVÁ Marie
Published: September 2021

Příspěvek se zaměří na formální morfologii v širším slova smyslu, tedy i na odvozování proprií, nejen na jejich skloňování, a to i se zřetelem k tendencím u apelativ. Budou se porovnávat propriální podoby systémové a novotvary užívané v současné komunikaci, shody a diference mezi apelativy a proprii. Klade se otázka, do jaké míry si současná čeština drží ohýbání jako podstatný rys flexivního jazyka a zda si udrží ohebnost u propriálních pojmenování, event. do jaké míry.
Egalitarian Trade Justice
Authors: Christensen James
Published: September 2021

This article begins by distinguishing between two approaches to egalitarian trade justice – the explicative approach and the applicative approach – and notes that the former has been used to defend conclusions that are less strongly egalitarian than those defended by advocates of the latter. The article then engages with the primary explicative account of trade egalitarianism – that offered by Aaron James – and argues that its egalitarian conclusions are unduly minimalistic. The aim of the article is not to criticize the explicative approach, but rather to show that the arguments and commitments of its best-known defender – James – either fail to rule out, or in fact positively support, more robustly egalitarian conclusions.
Acoustic absorption and thermal insulation of wood panels: Influence of porosity
Authors: Bertolini Marilia da Silva , de Morais César Augusto Galvão , Christoforo André Luis , Bertoli Stelamaris Rolla , dos Santos Wilson Nunes , Lahr Francisco Antonio Rocco
Published: September 2021

The development of materials that offer environmental comfort inside buildings, through adequate thermal and acoustic behavior, has been as relevant as the search for raw materials of renewable origin. In this context, this study produced and characterized panels made with Pinus sp. waste materials, which were treated with a copper chrome boric oxide preservative and a castor-oil based polyurethane resin. The physical and mechanical properties of the panels were evaluated according to the ABNT NBR 14810 standard (2013). The panel porosity was investigated by scanning electron microscopy (SEM) and mercury intrusion porosimetry techniques. The sound absorption was analyzed by a reverberation chamber and thermal conductivity by the modified fractionated column method. Samples with a higher pressing pressure (4 MPa) during the manufacturing presented lower thickness swelling and higher mechanical properties in static bending. Panels made with a lower press pressure (2.5 MPa) resulted in a higher porosity volume (55.7%). The more highly porous panels were more acoustically efficient, with a sound absorption coefficient close to 0.8 at 3.2 kHz, and they had a better thermal conductivity performance.The potential of these panels for application where sound absorption and thermal insulation are prioritized is thus observed.
Concílio Vaticano II, aggiornamento e diálogo
Authors: Gomes Tiago de Fraga , Zatti Daniel D’Agnoluzzo
Published: September 2021

O aggiornamento eclesial intencionado pelo Concílio Vaticano II aprofunda a autoconsciência da Igreja em ser serva da humanidade. Essa nova postura propicia que a igreja se aproxime e dialogue com a sociedade contemporânea. A presente pesquisa pretende abordar, brevemente, o impulso conciliar e pós-conciliar na relação entre o magistério da Igreja e as ciências naturais. Para isso, percorre o cenário pré-conciliar a partir de alguns pronunciamentos oficiais do magistério eclesial, os quais refletem uma postura paradoxal de desconfiança e abertura. Em seguida, o foco é o Concílio Vaticano II, especialmente a Gaudium et Spes que reconhece a autonomia das realidades terrenas como paradigma da relação entre o magistério eclesial e as ciências naturais. Por fim, são analisados alguns textos magisteriais pós-conciliares até o presente.
Ab initio study of the effect of 2D layer rippling on the electronic properties of 2D/H-terminated diamond (100) heterostructures
Authors: Mirabedini Pegah S. , Neupane Mahesh R. , Greaney P. Alex
Published: September 2021

We report an ab initio study of the effect of rippling on the structural and electronic properties of the hexagonal Boron Nitride (hBN) and graphene two-dimensional (2D) layers and heterostructures created by placing these layers on the Hydrogen-terminated (H-) diamond (100) surface. Surprisingly, in graphene, rippling does not open a band gap at the Dirac point but does cause the Dirac cone to be shifted and distorted. For the 2D/H-diamond (100) heterostructures, a combined sampling and a clustering approach were used to find the most favorable alignment of the 2D layers. Heterostructures with rippled layers were found to be the most stable. A larger charge transfer was observed in the heterostructures with rippled hBN (graphene) than their planner counterparts. Band offset analysis indicates a Type-II band alignment for both the wavy and planar heterostructures, with the corrugated structure having stronger hole confinement due to the larger valence band offset between the hBN layer and the H-diamond (100) surface.

Graphic abstract
Antimicrobial activity and chemical constitution of essential oil from Moroccan thyme (Thymus satureioides C.) on five microbial contaminants
Authors: OULED TAARABT Kamal , OUAABOU Rachida , LAHLALI Rachid , ENNAHLI Said
Published: September 2021

Antimicrobial preservatives are widely added to health products to prevent microbial contamination. However, because of the risks attributed to several synthetic agents, manufacturers are searching for new natural agents. Therefore, this work investigated the different physicochemical characteristics of one of those natural ingredients, the essential oil (EO) of Moroccan thyme (Thymus satureioides C.) and its antimicrobial potential against five microbial strains. The physicochemical parameters (density, refractive index, optical rotation, miscibility, acid value, ester value, and flash point) were measured and the chemical composition was determined by GC/MS. The antimicrobial activity was assessed using disc diffusion method and a macrodilution broth method. The EO yield was 1.01% compared to the dry matter. Fifty-two compounds were identified. The major compounds were thymol (28.66%), borneol (21.16%) and α- terpineol (12.33%). The disc diffusion method revealed that all the strains tested showed sensitivity to the EO at concentration of 1636 μg per disc. For the minimum inhibitory concentration (MIC) and the minimum microbicidal concentrations (MMC), similar results were obtained for Staphylococcus aureus and Escherichia coli (640 μg/mL), for Pseudomonas aeruginosa (960 μg/mL) and for Candida albicans (800 μg/mL) baring Aspergillus brasiliensis, which had 480 μg/mL and 640 μg/mL for the MIC and MMC, respectively.
Vulvo-vaginal myiasis among rural women in West Bengal, India
Authors: MONDAL Prabhat C. , MAHATO Santanu , SAHIS Dinabandhu , CHAKRABORTY Barunodoy , MONDAL Rajendra P. , HAZARI Pravas , SINHA Shuvra K.
Published: September 2021

Myiasis, the infestation of living or dead tissue of vertebrates by larvae (maggots) of dipterous flies, is well-known in the medical field. Different parts of the human body, such as skin, oral, nasal, urogenital are affected and named accordingly. The present study was a clinic-entomological study where the women having vulvo-vaginal myiasis were included. Maggots were collected, cultured, and adult flies were identified. A total of 34 cases of vulvo-vaginal myiasis were treated. The larvae of 29 cases were cultured into adults. Most of the women are rural (94%), illiterate and from a low socioeconomic society. The authors specified the infested sites of vulva and vagina such as vaginal, labia, clitoris, episiotomy wound, vulval growth, and prolapsed uterus. The episiotomy wound (32%) is the most common infestation site, followed by the vagina (26%). Chrysomya bezziana (76%) and Chrysomya megacephala (24%) are the identified flies. Illiterate, rural puerperal mothers of low socioeconomic status without proper health education and basic hygiene knowledge are vulnerable to myiasis.
In silico computation of coagulation factor II: a potential water treatment agent against gram negative bacteria
Authors: NATASYA Nadya , TERA Tyniana , SAVERO Sava , SWASTIKA Nadine , PARIKESIT Arli Aditya
Published: September 2021

Water, as one of the main sources of life, is an important aspect to public health and safety. Up until now there have been many concerns about water pollution especially in developing countries. Heavy polluted water that is not treated well could cause many concerning diseases that can lead to deaths. Contaminants that are of chemical, physical, and biological origins are commonly found in these water sources. Gram negative bacteria (GNB) have been seen to develop multiple drug and antibiotic resistance, causing more fatal infections. This has become a major concern of public health especially as it makes water treatment more challenging. Our study investigates human coagulation factor II that is responsible for blood clotting as a possible method for water treatment against GNB. By investigating the coagulation protein interaction with several bacterial lipopolysaccharides proteins and calculating the binding affinity of the interaction, the results show factor II has a lower binding affinity compared to previously studied factor VII. This shows possibilities of factor II to hydrolyse several gram-negative bacteria to act as a potential treatment against these GNBs.
Persistence, dissipation behavior and health risk assessment of spiromesifen in brinjal (Solanum melongena L.) by LC-MS/MS
Authors: SINGH Susheel , SOLANKI Vanrajsinh , KANSARA Rohan , PATEL Nitisha , GANDHI Kelvin , PATEL Hemant
Published: September 2021

Brinjal (Solanum melongena) is a versatile crop infected by several insects and pests. For the control of these pests, spiromesifen insecticide has been in use to reduce the damage and increase crop production worldwide. Therefore, a field trial was conducted to study dissipation and persistence behavior of spiromesifen 22.9% w/w SC in/on brinjal at the recommended dose (RD) 96 g a.i./ha and double to recommended dose 192 g a.i./ha (2RD). The quantitative analysis of spiromesifen was performed using ultra-high performance liquid chromatography- tandem mass spectrometry (UHPLC-MS/MS). Samples were processed by the Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) method. The analytical method was validated using various parameters viz., linearity (R2≥0.99), sensitivity (LOD and LOQ), accuracy (recovery=70-120%) and precision (RSD≤20%). The spiroemsifen persisted up to 3 days at RD and 5 days at 2RD. The dissipation half-life (DT50) of spriromesifen was 3.64 and 4.10 days at RD and 2RD in brinjal, respectively. However, residues of spiromesifen measured from soil at 0th (2 hr) day and 10th day were below the limit of quantification (BQL). The waiting period deciphered for spiromesifen applied in brinjal was 1 day at the recommended dose. Further, health risk assessment (health risk index<1 and percent health index<100) was performed on the basis of field trial which suggested that the application of spiromesifen in brinjal crop at recommended dose is safe for the end-users.
Phylogenetic analysis of the genus Conringia Heist. Ex Fabr. (Brassicaceae) in Turkey based on nuclear (nrITS) and chloroplast (trnL-F) DNA sequences
Authors: SEVINDIK Emre , AYDOGAN Melike , PAKSOY Mehmet Y.
Published: September 2021

In this study, phylogenetic analysis of Turkish Conringia (Brassicaceae) species was conducted based on nuclear ribosomal DNA (nrITS) and chloroplast DNA (trnL-F) sequences. In addition, the relationships between the sequences of some Brassicaceae family species retrieved from NCBI, and Conringia species were documented. All of the plant specimens were collected at their flowering and vegetation periods from different regions of Turkey, and brought to the laboratory. Total genomic DNA was extracted using the GeneMark kit. In PCR analyses, ITS4 and ITS5A primers were used for the amplification of the nrITS region, while the trnLe and trnLf primers were used for the cpDNA trnL-F region. The DNA sequences obtained were then edited using BioEdit and FinchTV, and analyzed using MEGA 6.0 software. Neighbor joining (NJ) and bootstrap trees were constructed in order to identify the relationships among Conringia taxa. The nrITS sequences ranged between 573 and 672 nucleotides, while the trnL-F sequences ranged between 346 and 764 nucleotides. The divergence values of nrITS sequences differed between 0.177 and 0.00 and divergence values of trnL-F sequences differed between 0.902 and 0.00. NJ tree generated using nrITS and trnL-F sequences consisted of two clades. In trees generated with both the nrITS and trnL-F sequences, C. orientalis, C. grandiflora and C. austriaca appeared within the same group. In addition, according to the phylogenetic analysis results obtained with other Brassicaceae species, it is revealed that the Conringia genus is polyphyletic.
Making Rain
Authors: Niglas Liivo , Storaas Frode
Published: September 2021

The Vumba Hills in central Mozambique, close to the Zimbabwe border, are the kingdom of Mambo (Chief) Chirara. The Mambo’s leading position is acknowledged by the government, and in addition to being the region's most important spiritual leader, the Mambo has the right to hold court cases that deal with minor crimes, problems involving spirits and domestic affairs. He is assisted by several subchiefs and ritual leaders. In the northernmost corner of the Mambo’s kingdom, Mbuya Gondo, an over 70-years-old woman, is a spiritual medium. She often holds ceremonies at a well-known rock drawing site. Mambo Chirara is not pleased with the old lady's activities. In his opinion, Mbuya Gondo acts too independently and demands too much money for carrying out the ceremonies. In the film, gender issues and local politics are brought to the surface as we follow these two leaders during a period of preparing for and performing the annual rainmaking rituals. The film is based on the fieldwork and archaeological research of Tore Sætersdal and Eva Walderhaug Sætersdal.
Use of contrast-enhanced ultrasound in pediatrics
Authors: Takahashi Marcelo Straus , Yamanari Mauricio Gustavo Ieri , Suzuki Lisa , Pedrosa Ésio Fortaleza Nascimento Chaves , Lopes Roberto Iglesias , Chammas Maria Cristina
Published: September 2021

Abstract Although contrast-enhanced ultrasound has been shown to provide considerable benefits, particularly in pediatric patients, it is still used relatively rarely in Brazil. It has proven to be a safe technique, and adverse effects are rare. In this review, we address the technique and main applications of contrast-enhanced ultrasound in the pediatric population, including the evaluation of focal liver lesions, abdominal trauma, kidney grafts, liver grafts, bowel loops, and vesicoureteral reflux. It is important for pediatric radiologists to be acquainted with this promising tool, understanding its applications and limitations.
Computed tomography features of cerebrovascular complications in intensive care unit patients with severe COVID-19
Authors: Alves Vinícius de Padua Vieira , Altoé Ananda , Veloso Vanessa , Ferreira Clecia Lucia Santos , Ventura Nina , Corrêa Diogo Goulart
Published: September 2021

Abstract Objective: To report the computed tomography (CT) features of acute cerebrovascular complications in severely ill patients with confirmed coronavirus disease 2019 (COVID-19) in the intensive care unit. Materials and Methods: We conducted a retrospective analysis of 29 intensive care unit patients with confirmed COVID-19 who underwent CT of the brain. We describe the CT features of the cerebrovascular complications of COVID-19, as well the demographic characteristics and clinical features, together with the results of laboratory tests, such as complete blood cell count, coagulation testing, renal function testing, and C-reactive protein assay. Results: Two patients were excluded because of brain death. Among the remaining 27 patients, CT revealed acute cerebrovascular complications in six (three men and three women; 49-81 years of age), whereas no such complications were seen in 21 (15 men and six women; 36-82 years of age). Conclusion: Radiologists should be aware of the risks of cerebrovascular complications of COVID-19 and the potential underlying etiologies. COVID-19-associated coagulopathy is likely multifactorial and may increase the risk of ischemic and hemorrhagic infarction.
Potential of Kazakhstan’s grain export trade
Authors: Wang Yameng , Huang Peipei , Khan Zaid Ashiq , Wei Feng
Published: September 2021

ABSTRACT: Kazakhstan is located in the hinterland of Central Asia. Its virtuous geographical advantages and huge grain production potential make it one of the most important grain exporters in the world. The research on the problem of the grain trade in Kazakhstan is of great significance for food security. This study measured its international competitiveness using the International Market Share Index, the Revealed Comparative Advantage Index, Trade competitiveness index and calculated the international competitiveness and analyzed the influencing factors of grain export by constructing an extended gravity model and measured its export potential. Results showed that Kazakhstan has a low share of the international grain market; however, wheat, barley, and buckwheat have strong export advantages; the level of economic development and economic distance has significantly promoted the scale of grain exports. While geographical distance, the difference in GDP per capita, and the fact whether trading partner countries have joined the Eurasian Economic Union have caused obstacles to grain exports. Kazakhstan’s export potential to 6 countries including Russia, Kyrgyzstan and China shows an upward” trend, its export potential to 6 countries including Tajikistan and Ukraine showing a “stable” trend, and its export to 9 countries included Poland and Germany. The potential showed a “declining” trend.
COMPARISON OF TWO METHODS OF FIXATION OF SUPRACONDYLAR FRACTURES OF THE HUMERUS IN CHILDREN
Authors: NATALIN HENRIQUE MELO , SILVA JÉSSICA COLAMARINO SESSA DA , VOLPON JOSÉ BATISTA
Published: September 2021

ABSTRACT Objective: To compare the outcomes of the fixation of complete and displaced supracondylar humeral fractures in children with two different Kirschner wire configurations. Methods: The type of fixation was randomized to either crossed (19 cases), or two divergent lateral Kirschner wires (24 cases). The comparison was made six months later between the two treated groups and each group with the non-fractured elbow (clinical alignment, range of motion, Baumann angle, and lateral humeral capitellar angle). Results: 43 children were evaluated (65% boys) with a mean age of six years and five months. The carrying angle (p = 0.94), extension (p = 0.89), and the Flynn´s criteria (p = 0.56) were similar between the groups. The flexion was slightly smaller for the crossed wire group (p = 0.04), but similar to the uninjured side. The Baumann angle was not different between the two fixations (p = 0.79) and the contralateral side (p = 0.1). The lateral humeral capitellar angle was slightly greater for the lateral pinning (p = 0.08), but with no difference with the uninjured elbow (p = 0.62). No iatrogenic injuries were observed. Conclusion: Both fixations presented similar outcomes that did not significantly affect the carrying angle in relation to the non-fractured side. Level of evidence II, Therapeutic study - Investigating the results of treatment.
ANATOMICAL STUDY OF THE POSTEROLATERAL LIGAMENT COMPLEX OF THE KNEE: LCL AND POPLITEUS TENDON
Authors: SOBRADO MARCEL FARACO , HELITO CAMILO PARTEZANI , MELO LUCAS DA PONTE , ASPERTI ANDRE MARANGONI , GOBBI RICCARDO GOMES , ANGELINI FABIO JANSON
Published: September 2021

ABSTRACT Objective: To analyse the distances between the femoral insertions of the popliteus tendon (PT) and the lateral collateral ligament (LCL) through dissections of cadaveric specimens in a mixed population. Methods: Fresh cadavers were dissected, and the anthropometric data of all specimens were recorded. The distances from the origin of the PT to the LCL in the femoral region and the diameter of each structure were measured using a digital calliper. Results: In total, 11 unpaired knees were dissected, eight men and three women, with an average age of 71.5 ± 15.2 years, weight of 57.2 ± 15.6 kg, and a mean height of 170.5 ± 8.2 cm. The distance from the center of the femoral footprint of the LCL to the PT was 10.0 ± 2.4 mm. The distances between the edges closest to each other and those more distant from each other were 3.1 ± 1.1 mm and 16.3 ± 2.4 mm, respectively. Conclusion: The distance between the midpoints of the PT and the LCL in our mixed population is smaller than the distances often reported in the literature. PLC reconstruction with separate tunnels for the LCL and PT may not be technically possible for individuals of any population. Level of Evidence III, Diagnostic studies.
FROM GARRINCHA’S LEGS TO NEYMAR’S LEGS: THE GENU VARUM AND VALGUM IN SOCCER. HISTORICAL OVERVIEW AND UPDATE
Authors: CARDOSO FABRÍCIO LUZ , SENEME ENRICO DE LOSSO , SILVA MARCOS VINÍCIUS MURIANO DA , LARAYA MARCOS HENRIQUE FERREIRA , GALBIATTI JOSÉ ANTONIO , YANASSE RICARDO HIDEKI
Published: September 2021

ABSTRACT The presence of abnormalities in knee alignment (genu varum and genu valgum) is extremely common in soccer. It can occur in the junior league / youth academy and perpetuate itself throughout the professional career. The consequences of years of high-level sports practice in players with genu varum / genu valgum can be harmful to the knees. By observing football matches of the present and the past, the authors of the article noted that great Brazilian soccer players were, or are, affected by the malalignment of the knees: Garrincha (the most famous), Leandro, Dunga, Romário, Rivaldo and Neymar. This study aims to discuss the relationship between high-performance sport and the development of these orthopedic deformities, serving as a tool for updating the trauma-orthopedic knee subspecialty. Level of Evidence III, Retrospective comparative study.
BENEFITS OF THE WALANT TECHNIQUE AGAINST THE COVID-19 PANDEMIC
Authors: ALVES RAFAEL SALEME , CONSONI DANIEL ALEXANDRE PEREIRA , FERNANDES PEDRO HENRIQUE OLIVEIRA , SASAKI SANDRA UMEDA , ZAIA ISABELLA MARTINS , SANTOS SOFIA BRANDÃO DOS , SATO MONICA AKEMI
Published: September 2021

ABSTRACT Objective: Evaluate the experience of private and public health services with the WALANT procedure in the COVID-19 pandemic. Methods: This is a retrospective, multicenter longitudinal study gathering cases of hand surgery subjected to the WALANT technique in the Hospitals Dr. Radamés Nardini and IFOR during the COVID-19 pandemic (August 2020). As a parameter, the verbal numerical rating scale for twenty patients referring to the preoperative, intraoperative and postoperative periods was applied. Results: The patients did not feel any pain during surgery, which showed the efficiency of the anesthetic technique in its purpose. Conclusion: The results indicate the WALANT technique as beneficial when facing the COVID-19 pandemic, as the main differential of the technique is that it is applied by a well-trained orthopedic hand surgeon. Level of Evidence IV, Case Series.
Literacia para a saúde em países de renda baixa ou média: uma revisão sistemática
Authors: Pavão Ana Luiza Braz , Werneck Guilherme Loureiro
Published: September 2021

Resumo Literacia para a Saúde (LS) relaciona-se às capacidades individuais de acesso, compreensão, avaliação e aplicação das informações de saúde, a fim de se tomar decisões na vida diária, para manter ou melhorar a saúde. O objetivo deste artigo é revisar os estudos sobre LS conduzidos nos países de renda baixa ou média, com ênfase na definição utilizada para LS. Revisão sistemática nas bases de dados Medline, Embase, Scopus, LILACS e SciELO. Foram incluídos estudos que apresentavam a definição de LS, estudos em países de economias de renda baixa ou média e estudos latino-americanos. Inicialmente foi feita leitura dos títulos e/ou resumos. Dois avaliadores independentes realizaram a leitura do texto completo. Discordâncias foram discutidas por consenso. Foram encontradas 6.025 referências e selecionadas 36 para a amostra final. A maioria dos estudos (58,3%) era de países do continente asiático, seguidos pelos estudos em países da América do Sul (27,8%), incluindo o Brasil. A maior parte (58,3%) avaliou a dimensão funcional da LS (LFS). As definições mais frequentes foram do Instituto de Medicina dos Estados Unidos e da Organização Mundial de Saúde. Aproximadamente 30% dos estudos que avaliaram a LFS utilizaram como referencial teórico definições mais abrangentes de LS.
Tendências de acesso e utilização dos serviços de saúde na APS entre idosos no Brasil nos anos 2008, 2013 e 2019
Authors: Cesário Vanovya Alves Claudino , Santos Marquiony Marques dos , Mendes Tamires Carneiro de Oliveira , Souza Júnior Paulo Roberto Borges de , Lima Kenio Costa de
Published: September 2021

Resumo O artigo tem por objetivo contribuir na identificação das condições e tendências de acesso e utilização dos serviços da atenção primária em saúde (APS) pelos idosos brasileiros nos anos de 2008, 2013 e 2019. Um estudo transversal em painéis com análise descritiva dos percentuais e intervalos de confiança das variáveis elencadas, no qual foram resgatados os dados relativos à população idosa investigada no Suplemento Saúde da Pesquisa Nacional por Amostra de Domicílios (PNAD) do ano 2008 e da Pesquisa Nacional de Saúde (PNS) 2013 e 2019. Inicialmente identificou-se que, apesar da APS ter sido o principal serviço procurado mediante a necessidade de assistência, houve uma tendência de redução para esta procura em todas as regiões brasileiras, principalmente entre as mulheres idosas, na faixa etária de 60-69 anos e na população de raça/cor branca. Verificou-se um aumento de 15,2% no quantitativo de domicílios cadastrados na Unidade de Saúde da Família; 4,5% na procura por lugar, serviço ou profissional de saúde; e de 31,4% na população atendida. Os principais fatores de não atendimento foram não conseguir vaga/senha e não ter médico atendendo. E, dentre os investigados, verificou-se uma tendência de crescimento entre os que tinham o diagnóstico de hipertensão arterial sistêmica, diabetes mellitus e multimorbidades.
A two-step planning method to increase accessibility to medium complexity procedures for public secondary healthcare
Authors: Almeida João Flávio de Freitas , Campos Francisco Carlos Cardoso de
Published: September 2021

Abstract The specialized care level of the public Brazilian national health system is critical and chronically underfunded. Few studies have evaluated public secondary care planning on a strategic level, so there are open issues yet to examine. This study aims at locating medical centers and sizing equipment based on a two-step optimization process to meet the population’s needs. The models consider physicians’ propensity for working on a metropolis and the patients’ choice on moving the least from their municipalities, therefore, conflicting decisions. The models provide the location of medical centers, the assignment of equipment to such locations, and the additional hours of specialists required to meet official standards of demand. Available equipment with idle capacity should partly satisfy the requirement for exams within the current infrastructure. For the remaining uncovered demand, the second step of the optimization model suggests the acquisition of additional equipment for the elected medical centers to meet established needs. The proposed location of secondary care facilities covers 834 municipalities, corresponding to 97.77% of the estate, with an average patient displacement of 58.73 km (CI95%: 56.18 km - 61.28 km). In general, 39 out of 77 health regions should hire additional hours of medical specialties. Pediatrics and gynecology represent the major gap.