bluuebunny/crossref_metadata_2025 huggingface dataset:
Non-alcoholic Steatohepatitis: Comparison of Intestinal Microbiota between Different Metabolic Profiles. A Pilot Study
Authors: De Oliveira Juliano Machado , Pace Fábio Lima , Ghetti Fabiana De Faria , Barbosa Kátia Valéria Bastos Dias , Cesar Dionéia Evangelista , Chebli Júlio Maria Fonseca , Ferreira Lincoln Eduardo Villela Vieira de Castro
Published: August 2020

Background and Aims: Non-alcoholic steatohepatitis (NASH) has multifactorial etiopathogenesis, and intestinal microbiota is co-responsible in this process. The aim of this study was to evaluate the intestinal microbiota in NASH patients with different metabolic profiles.

Methods: Patients with biopsy-proven NASH were evaluated. Subjects were divided into two groups according to their metabolic profile, with or without metabolic syndrome (MS). Their characteristics in relation to liver disease and intestinal microbiota were analyzed. To evaluate the microbiota, breath tests to investigate small intestinal bacterial overgrowth (SIBO) and fecal microbiota analysis by fluorescence in situ hybridization (FISH) were performed.

Results: There was a high prevalence of SIBO in both groups, with no significant difference between them. Breathing tests were positive in 43.8% of patients with MS and 50% of those without MS. There was a significant difference regarding the quantification of Verrucomicrobiales, less abundant in patients with NASH without MS. Its lower concentration also correlated with higher serum ferritin levels and higher hepatocyte ballooning. This order of bacteria, through its representative in human microbiota, Akkermansia muciniphila, is associated with mucosal protection and metabolic processes with liver aggression.

Conclusions: Our results suggested that lower Verrucomicrobiales concentration is associated with higher inflammatory activity in patients with NASH without MS, where the disease etiopathogenesis does not have its classic metabolic substrate.
Effect of Light Sources on Bond Strength of Different Composite Resins Repaired with Bulk-Fill Composite
Authors: Kiliç Vahti , Hürmüzlü Feridun
Published: August 2020

The aim of this study was to evaluate and compare the effects of different light sources on shear bond strength when bulk-fill composite was used for the repair of different composite resins. A total of 126 samples made from six resin composites with different properties were aged (thermal-cycling with 5000 cycle), exposed to the same surface treatments and adhesive procedure. Then, they were repaired with a bulk-fill composite. At the polymerization step, each group was divided into three subgroups (n=7) and light cured with a QTH light source for 40s and two different LED light sources for 20s. Subsequently, the specimens were aged in distilled water at 37 ºC for 4 weeks and then subjected to shear bond strength test. Then, the specimens were examined under a stereomicroscope to identify modes of failure and visualized by Scanning Electron Microscope. Data obtained from the study were analyzed using ANOVA and Tukey HSD Test (α=0.05). In all groups, the light curing units had an impact on shear bond strength (p<0.05). Among the study groups, the greatest bond strength values were observed in the specimens repaired using the LED and the specimens repaired with the QTH light curing unit had the lowest bond strength values. It was concluded that the content of composite resins and light curing units may influence bond strength of different composites repaired with the bulk-fill composite.
Study of Urinary Alpha Glutathione-S-Transferase (Alpha GST) in Children with Idiopathic Nephrotic Syndrome
Authors: Abdel-Salam Manal , Allam Houriah Ahmed , Kholoussi Shams , Ibrahim Asmaa Abd El-Wakeel , El-Hakeim Shaimaa Adel Abd
Published: August 2020

Background: Glomerulopathy associated with recurrent or persistent proteinuria may lead to progressive tubulointerstitial fibrosis. Early detec-tion of tubulointerstitial fibrosis may result in a more favorable outcome of chronic kidney disease (CKD) because nephroprotective treatment may be instituted in due course. One of the early markers of tubulointerstitial fibrosis is glutathione S-transferase (GST).The aim: The aim of this study was to determine urinary alpha-GST in children with idiopathic nephrotic syndrome (INS), either in remission or relapse.
Material and methods: This case–control study included 40 children with primary nephrotic syndrome (NS), either in remission or relapse. Also, 40 healthy children, age- and sex-matched as controls, were selected from the outpatients and the pediatric nephrology unit of Al-Zahraa Hos-pital, Al-Azhar University. Urinary alpha-GST was investigated in the study groups on the same lines as that of routine investigations of INS.
Results: Children with INS have significantly higher urinary GST either in remission or relapse, it was (5.23 ± 1.90) ng/mL, (5.32 ± 1.52) ng/mL respectively compared with healthy controls, it was (2.59 ± 1.12) ng/mL with (P = 0.001). A positive correlation between urinary alpha-GST and body weight BW, height, body mass index (BMI), white blood cells (WBCs) count, erythrocyte sedimentation rate, serum (cholesterol, triglycer-ide [TG]) level, blood urea nitrogen (BUN), and duration of the disease.
Conclusion: Urinary alpha-GST was increased in children with NS even after remission, and it consequently led to oxidative stress and tubuloint-erstitial fibrosis. Nephroprotective treatment is recommended even in cases with INS, either in remission or relapse.
Tumescent anesthesia or epidural anesthesia combined with intercostal block in bitches submitted to mastectomy
Authors: Sanches Mariana Cardoso , Naspolini Barbara Machado , Maroneze Beatriz Persici , Salame Jéssica Paola , Guim Thomas Normanton , Gehrcke Martielo Ivan
Published: August 2020

Abstract The present study aimed to evaluate the use of tumescent local anesthesia or epidural anesthesia associated with an intercostal nerve block in bitches submitted to mastectomy. Fourteen bitches from the clinical routine of the Veterinary Hospital of the Federal University of Pelotas were premedicated with acepromazine (0.03 mg/kg) and morphine (0.3 mg/kg) intramuscularly, then induced with propofol (2 to 6 mg/kg/IV) and maintained with 1,4V% isoflurane (calibrated vaporizer). The patients were randomly allocated into: GALT Group (n=7), which received tumescent local anesthesia (0.16%) at the dose of 15 mL/kg, and the GEBI Group (n=7) which received epidural anesthesia with lidocaine (5 mg/kg) and morphine (0.1 mg/kg) associated with an intercostal nerve block from the 6th to 12th intercostal space with lidocaine (2 mg/kg). An increase higher than 10% in heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure were considered as possible signs of nociception, to which fentanyl was administered intravenously as rescue analgesia. Postoperative analgesia was evaluated by means of the modified Glasgow scale at 30, 60, 120, 240 and 360 minutes. There were no differences in physiological parameters (0>0.05) in the transoperative period intra-group and inter-group the groups. The GEBI Group required more frequent transoperative rescue analgesia (9) in comparison to the GALT Group (5), but with no statistical difference. During the postoperative period, there was no need for rescue analgesia in either group. Results suggest that epidural anesthesia associated with intercostal nerve block can be used as an alternative technique in patients with restrictions against the use of local tumescent anesthesia.
Active Teaching-Learning Strategies for Family Medicine Preceptors in the EURACT
Authors: Barreiros Bárbara Cristina , Diercks Margarita Silva , Biffi Maríndia , Fajardo Ananyr Porto
Published: August 2020

Abstract: Introduction: The Family Doctor (FD), whose scope of action is Primary Health Care (PHC), is a professional trained to care for people, their families, and communities. The best FD training should be performed through Medical Residency Programs in Family Medicine (MRPFM), an in-service teaching field where a preceptor, also a FD, accompanies the resident. A pedagogically well-trained preceptor can work in the learning process of young doctors, who in turn are able to develop the necessary skills to work as a future FD. Active Learning Methodologies (ALM) are based on critical pedagogy and work with problems for the development of teaching-learning processes. They seek the theory from the practice, thus preparing the students to become aware of their environment and act aiming at its transformation. ALMs are achieved in the pedagogical processes through Active Teaching-Learning Strategies (ATLS), which are effective pedagogical resources used by the preceptors in the residents’ daily training. They can be divided into two groups: Active Teaching-Learning Dynamics and Active Teaching Actions. This article reports on the effects of a training course for Family Medicine preceptors on the use of Active Teaching-Learning Dynamics and Active Teaching Actions. Method: Qualitative comparative case study using sociodemographic survey, individual semi structured interview and field notes. The information was examined under content analysis, having participated ten preceptors from four MRPFM from the state of São Paulo, Brazil (half having attended the Leonardo EURACT level 1 course and half not having done so). Results: Those preceptors who attended the course expressed having more knowledge and use of Active Teaching-Learning Strategies, specifically of Active Teaching-Learning Dynamics and Active Teaching Actions. Conclusions: It was observed that the Leonardo EURACT level 1 teaching technology modifies the teaching practice of those who took the course, as they demonstrate a greater use and domain of its tools in their pedagogical practice. Moreover, the course allows a greater understanding of the presented dynamics and activities, thus promoting the residents’ critical learning and encouraging autonomy.
The use of voice in higher education: What the professors have to say?
Authors: Medeiros Yuri Patrick Oliveira de , Nascimento Cynthia Maria Barboza do , Gomes Adriana de Oliveira Camargo , Lira Zulina Souza de , Araújo Ana Nery
Published: August 2020

ABSTRACT Purpose: to describe the perception of university professors regarding their use of voice at work. Methods: a total of 247 higher education professors participated in this study. They answered a questionnaire on voice complaints, in which three complaints or more were considered indicative of a voice disorder. After the professors with a potential voice disorder were identified, a conversational interview was conducted with five professors to learn more on their perceptions on the use of voice at work. The study was approved by the research ethics committee of the institution of origin. The data were quantitatively and qualitatively analyzed. Results: the age group 20 to 30 years old was the one that most presented voice problems. The most recently hired professors (up to five years of work), with a 40-hour weekly workload, were those who most reported voice complaints. The professors had a good perception of their voice and demonstrated good knowledge about it. Conclusion: although voice complaints were prevalent, the professors proved to be aware of how to take care of their voices.
Urine hepcidin, netrin-1, neutrophil gelatinase-associated lipocalin and C-C motif chemokine ligand 2 levels in multicystic dysplastic kidney
Authors: Cetin Nuran , Kiraz Zeynep Kusku , Sav Nadide Melike
Published: August 2020

ABSTRACT Introduction: Glomerular hyperfiltration may lead to proteinuria and chronic kidney disease in unilateral multicystic dysplastic kidney (MCDK). We aimed to investigate the urine neutrophil-gelatinase-associated lipocalin (NGAL), netrin-1, hepcidin, and C-C motif chemokine ligand-2 (MCP-1/CCL-2) levels in patients with MCDK. Methods: Thirty-two patients and 25 controls were included. The urine hepcidin, netrin-1, NGAL, and MCP-1/CCL-2 levels were determined by ELISA. Results: The patients had higher serum creatinine (Cr) levels, urine albumin, and netrin-1/Cr ratio with lower GFR. There were positive correlations between urine protein/Cr, MCP-1/CCL-2/Cr, and netrin-1 with NGAL (r = 0.397, p = 0.031; r = 0.437, p = 0.041, r = 0.323, p = 0.042, respectively). Urine netrin-1/Cr was positively correlated with MCP-1/CCL-2/Cr (r = 0.356, p = 0.045). There were positive associations between the presence of proteinuria and netrin-1/Cr, MCP-1/CCL-2/Cr, and NGAL/Cr [Odds ratio (OR): 1.423, p = 0.037, OR: 1.553, p = 0.033, OR: 2.112, p = 0.027, respectively)]. ROC curve analysis showed that netrin-1/Cr, MCP-1/CCL-2/Cr, and NGAL/Cr had high predictive values for determining proteinuria p = 0.027, p = 0.041, p = 0.035, respectively). Urine hepcidin/Cr was negatively correlated with tubular phosphorus reabsorption and was positively correlated with urine NGAL/Cr (r = -0.418, p = 0.019; r = 0.682, p = 0.000; respectively). Conclusions: MCP-1/CCL-2 may play a role in the development of proteinuria in MCDK. Netrin-1 may be a protective factor against proteinuria-induced renal injury. Urine hepcidin/Cr may reflect proximal tubule damage in MCDK. Urine NGAL/Cr may be a predictor of tubule damage by proteinuria.
Chemical properties of pore solution of hardened cement pastes with mineral additions
Authors: Cherif Rachid , Hamami Ameur El Amine , Aït-Mokhtar Abdelkarim , Siddique Rafat
Published: August 2020

This paper presents the influence of mineral additions in blended cement, or ‘green’ concrete, on the divalent ions of the cement paste pore solution. Because of the lack of data concerning the direct comparison between the pore solution of cement and mineral additions-based material, six types of hardened cement pastes were tested. For this purpose, Portland cement (CEM I or CEM V) and mineral additions (limestone filler, fly ash, blast-furnace slag and silica fume) were used. Results from chemical analyses by ionic chromatography show significant concentrations of divalent ions, such as sulfates and calcium, in the pore solution. In fact, the reference cement paste based on CEM I contains about 1.8 mmol/l of calcium and 1.6 mmol/l of sulfates. However, the use of mineral addition significantly modifies the pore solution. In particular, a substitution of cement by 10% of silica fume increases the calcium and sulfates concentrations to 12.2 mmol/l and 6.7 mmol/l, respectively. This change in the chemical composition, the pH and the ionic strength should be taken into account in multispecies transfer modelling and the thermodynamic equilibrium. The time evolution of the chemical composition, pH and ionic strength of the pore solutions was also investigated.
Wave–structure interaction of wave energy converters: a sensitivity analysis
Authors: Windt Christian , Davidson Josh , Schmitt Pál , Ringwood John V.
Published: August 2020

Measurement uncertainties are inevitable during physical wave tank tests. Therefore, when validating a numerical wave tank against experiments, knowledge of the uncertainties in the physical experiments, and the sensitivity of the body dynamics to such uncertainties, is crucial. Specifically, the inertial properties, as well as the location of the centre of mass (CoM), which are challenging to measure accurately, can have a significant influence on the system dynamics. On the basis of test cases of the Collaborative Computational Project in Wave Structure Interaction Blind Test Series 2, this paper presents a sensitivity analysis of the agreement between experimental and numerical data sets to the quality of the incident, focused wave, as well as the inertial properties and the location of the CoM. A significant influence on the modelled system dynamics can be observed when changing the system parameters, resulting in a variation of the observed error of up to 80 percentage points for pitch motion.
Comercio agrícola en el tratado de asociación estratégica entre Unión Europea y MERCOSUR: ¿el talón de Aquiles del acuerdo o la razón de la unión?
Authors: Botero Botero Laurita , Guzmán María Florencia
Published: August 2020

La firma del Tratado de Asociación entre Unión Europea y MERCOSUR cerraría décadas de negociaciones descontinuas entre ambos bloques. Se trata de un acuerdo de asociación multitemático que incluye negociaciones comerciales como también compromisos políticos y de cooperación. Sin embargo, existe un conflicto de intereses entre los bloques, específicamente el comercio agrícola, que sigue siendo el talón de Aquiles de la consecución del Tratado y la limitante de una ratificación completa del acuerdo. Este artículo pretende explicar los compromisos adquiridos por la UE y el MERCOSUR sobre comercio agrícola en el Acuerdo, además de analizar las ventajas y desventajas que suponen la implementación del mismo para el bloque europeo y el sudamericano. Por último, exponer el posicionamiento de cada uno de los bloques en lo referente a la ratificación e implementación de este tratado de integración económica.
O papel da governança das instituições consultivas: União Europeia e MERCOSUL
Authors: Siman Tainá
Published: August 2020

A participação de atores descentralizados nas integrações regionais tem ganhado um papel relevante não somente na tomada de decisões dentro da instituição ao longo dos anos, mas tem também chamado a atenção de parte da comunidade acadêmica. O desenvolvimento da sociedade civil tomou forma de sindicatos, ONG’s, OI’s, associações, entre outros, que encontraram através da organização formal uma maneira de se infiltrar e institucionalizar sua influência e participação dentro dos mecanismos das integrações regionais. Tendo como principais órgãos de representação de nível subnacional o Comitê das Regiões (CdR) e da participação civil o Comitê Econômico e Social Europeu (CES), o presente artigo busca investigar qual o papel das ações desses órgãos junto ao conjunto da União Europeia. No caso do MERCOSUL, serão analisados o Foro Consultivo de Municípios, Estados Federados, Províncias e Departamentos do MERCOSUL (FCCR) e o Foro Consultivo Econômico e Social (FCES). Para isso, utilizamos uma tipologia que define a sociedade civil em quatro papeis: parceira, legitimadora, manipuladora e contestadora. A primeira sessão do artigo define e explora essas tipologias, enquanto as seções seguintes buscam investigar a origem, principais atores, e o grau de autonomia dos órgãos supracitados. Nas considerações finais busca-se, a partir das características levantadas sobre as instituições, associá-las às tipologias afim de refletir quais interações e pressões dessas agências sobre a União Europeia e o MERCOSUL.
Futurología sobre las normas internacionales
Authors: Arbuet-Vignali Heber
Published: August 2020

El autor procura dar su visión del futuro de las relaciones internacionales, sostiene la necesidad de someterlas a algún tipo de derecho constitucional y pronostica graves consecuencias para el caso de no hacerlo. Expone la experiencia en que funda su pronóstico y lo respalda, además, con un prolijo análisis de los dos opúsculos que Emmanuel Kant dedica específicamente al estudio del tema.
HTAPP_Dissociation of human primary lung cancer resection to a single-cell suspension for single-cell RNA-seq v2
Authors: Slyper Michal , Waghray Avinash , Waldman Julia , Wakiro Isaac , Su Mei-Ju , Vigneau Sébastien , Rotem Asaf , Johnson Bruce , Rozenblatt-Rosen Orit , Regev Aviv
Published: August 2020

This protocol is used for the dissociation of human primary lung cancer resections to a single-cell suspension compatible with droplet-based single-cell RNA-Seq technology. For the Human Tumor Atlas Pilot Project (HTAPP) it has been successfully applied to non-small cell adenocarcinoma from which it was able to capture a diversity of cell types, including malignant (epithelial) and non malignant cells such asmesenchymal, endothelial, myeloid, and lymphoid cells. In some instances, this protocol can be combined with a protocol for CD45-cell depletion, which is used for fast depletion of immune cells for enrichment of malignant and stromal cells. Description of this protocol and guidance for testing and selecting methods for processing other tumor and sample types can be found in Slyper et al.
Direct ELISA for investigating the binding of Peptostreptococcal Protein-L to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel , F. Smikle Monica
Published: August 2020

Peptostreptococcal protein L is an immunoglobulin-binding protein that interacts with the Fab region of many mammalian immunoglobulins [1]. References 1.Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
Direct ELISA for investigating the binding of recombinant Protein-LA to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel , F. Smikle Monica
Published: August 2020

Referencesst protein LA (SpLA) is an immunoglobulin-binding protein that interacts with the Fab and Fc regions of many mammalian immunoglobulins [1]. References 1.Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
Direct ELISA for investigating the binding of recombinant or chemically-made Protein-LG to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

Protein LG (SpLG) is an immunoglobulin-binding protein that interacts with the Fab and Fc regions of many mammalian immunoglobulins [1]. References 1.Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
Direct ELISA for investigating the binding of recombinant or chemically-made Protein-AG to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

Protein AG (SpAG) is an immunoglobulin-binding protein that interacts with the Fc regions of many mammalian immunoglobulins [1]. References 1.Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
Copy of Direct ELISA for investigating the binding of chemically-made Protein-LAG to immunoglobulins. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

Protein LAG (SpLAG) is an immunoglobulin-binding protein that interacts with the Fc and Fab regions of many mammalian immunoglobulins. It is produced by a chemical coupling of individual proteins and them mixing it up to the appropriate protein ratio. SpLAG binds well to some avian immunoglobulin [1]. References 1.Vaillant AJ, McFarlane-Andersonv N, Wisdom B, Mohammed W, Vuma S, et al. (2013) Immunoglobulin-binding Bacterial Proteins (IBP) Conjugates and their Reactivity with Immunoglobulin in Enzyme-Linked Immunosorbent Assays (ELISA). J Anal Bioanal Tech 4: 175. doi:10.4172/2155-9872.1000175
ELISA for quantification of IL-6 in human serum or plasma. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

Interleukin-10 is a pleiotropic cytokine playing a critical role as a regulator of myeloid and lymphoid cell function. Due to the ability of IL-10 to blocking cytokine synthesis and many accessory cell functions of antigen-presenting cells such as macrophages this cytokine is a potent suppressor of the effector functions of macrophages, T-cells and NK cells. IL-10 also participates in regulating proliferation and differentiation of B-lymphocytes, mast cells and thymocytes [1]. Reference 1. Ouyang W, O'Garra A. IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation.Immunity. 2019;50(4):871-891. doi:10.1016/j.immuni.2019.03.020
Enzyme linked immunosorbent assay (ELISA) for determining the serum concentration of IL-17 in humans. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

Interleukin17A is a pro-inflammatory cytokine. This protein is produced by a group of T helper cell known as T- helper17 lymphocytes in response to their stimulation with IL-23. After interaction with its receptor, IL-17 activates signalling pathways that stimulate the production of chemokines [1 ]. Reference 1. Cho ML, Kang JW, Moon YM, Nam HJ, Jhun JY, Heo SB, Jin HT, Min SY, Ju JH, Park KS, Cho YG, Yoon CH, Park SH, Sung YC, Kim HY (May 2006). Journal of Immunology. 176 (9): 5652–61.
Improved protocol of ELISAfor determining the serum concentration of IL-23 in humans. v1
Authors: A Justiz-Vaillant Angel
Published: August 2020

A previous protocol was contaminated with IL-17. This is an improved version of an ELISA for quantification of Interleukin 23. It activates the production of IL-17A, which is a pro-inflammatory cytokine, produced by a group of T helper cell known as T- helper17 lymphocytes in response to the said IL-23 [1,2]. Reference 1. Cho ML, Kang JW, Moon YM, Nam HJ, Jhun JY, Heo SB, Jin HT, Min SY, Ju JH, Park KS, Cho YG, Yoon CH, Park SH, Sung YC, Kim HY (May 2006). Journal of Immunology. 176 (9): 5652–61. 2. Nobee A, Justiz-Vaillant A, Akpaka PE, Poon-King P (2016) Levels of Interleukin 17 and 23 in Patients with Systemic Lupus Erythematosus (SLE) in Trinidad and Tobago. Immunochem Immunopathol 2: 115. doi: 10.4172/2469- 9756.1000115
MATERIALS FOR THE QUESTION ABOUT EXTRAUTERINE PREGNANCY
Authors: Ivanov A. I.
Published: August 2020

MATERIALS FOR THE QUESTION ABOUT EXTRAUTERINE PREGNANCY
New bedpan
Authors: Hermonius A.
Published: August 2020

This vessel is especially useful for all types of urinary incontinence in women (after belly, with neoplasms in the urethra, etc., likewise, with various cerebral suffering and paralysis of the bladder)
Two cases of ectopic pregnancy, successfully operated
Authors: Lapina A.
Published: August 2020

Mrs V. N., 27 y., Regulations with 13 y., Married, 11-para, had two miscarriages. After the second miscarriage (1890), the regulations became incorrect: they were late in time, in smaller quantities and were accompanied by severe pain. The last blood was in May 1891 and appeared after 5 weeks, in small quantities.
Innovación en turismo: polo gastronómico Tomás Jofré – Buenos Aires, Argentina
Authors: Thiel Ellul Daniela
Published: August 2020

La importancia y el reconocimiento que el turismo está adquiriendo en el mundo y, particularmente en la Argentina, motiva a nuevos lugares a incorporar esta actividad como estrategia para su desarrollo. Las particularidades del sector obligan a pensar creativamente e innovar para estar vigentes en esta actividad. El presente artículo pretende mostrar cómo el sector turístico argentino se está reinventando mediante el estudio de lo acontecido en un pueblo,Tomás Jofré, que ha sido pionero en la innovación y, transformándose en un afamado polo gastronómico, introdujo la actividad turística como principal fuente de desarrollo de la localidad.
Ética de la empresa y estrategias empresariales
Authors: Comite Ubaldo
Published: August 2020

El tema de la ética afecta al mundo de las organizaciones productivas, y se propone valorar su compatibilidad con la creación del valor, entendida como mayor producción obtenida respecto al valor de los recursos empleados, objetivo final de cualquier ente productivo. La ética de la empresa significa un verdadero estímulo para las reflexiones sobre la delicada relación empresa - entorno, caracterizada por la necesidad de elaborar estructuras normativas y modelos de reflexión en los que basar las políticas, la gestión y el comportamiento comunes. Ante estas evidencias, está claro que es oportuno dar una nueva orientación a la cultura empresarial, para ir más allá de la mera venta del producto, situando al cliente en el centro de la organización, pasando de ser una organización "tecnology driver" a ser "customer focused". Se trata de un desafío que en estos años han afrontado muchas organizaciones, pero sin ir más allá de la enunciación de los principios. En efecto, la mayor dificultad reside en concretar los principios en comportamientos eficaces y difusos. La satisfacción del cliente sólo es el punto de partida para la construcción de una relación estable, pero no es suficiente, mientras que es esencial focalizar la atención en un factor que ciertamente influye en el valor global de la empresa: la fidelidad de los clientes (customer loyalty). En este estudio, se analiza el caso de la fidelity card en la experiencia italiana, considerada una herramienta (canal), a través de la cual la empresa puede actuar sobre los elementos subyacentes de la confianza (los llamados driver) y poner en marcha la relación con el cliente final. La tarjeta de fidelidad se convierte a todos los efectos en el vehículo de la relación fiduciaria entre el cliente y el distribuidor. Sin embargo, se trata de una herramienta de una relación fiduciaria sólamente potencial cuando falta una actividad consciente dirigida a explotar las oportunidades emergentes.
Una aproximación teórica a la relación de la empresa turística con la ética y la responsabilidad social
Authors: Ledesma Alicia
Published: August 2020

Dadas las condiciones imperantes de sostenibilidad global es conveniente encontrar otros paradigmas que permitan el estudio del impacto y la generación de negocios turísticos inclusivos y equitativos. En otras palabras, se debe pensar a los negocios turísticos desde una concepción basada en valores éticos y sociales, que desarrollen vínculos interdisciplinarios y analicen las cuestiones sociales, económicas, históricas, culturales y naturales (medioambientales) presentes en la consolidación de todo desarrollo turístico verdadero. Mediante una aproximación teórica, este trabajo intenta traer una reflexión sobre la relación que existe entre la empresa turística, la sociedad la ética y la responsabilidad social.
Los rostros silenciados de la responsabilidad
Authors: De la Cruz Ayuso Cristina
Published: August 2020

Este artículo ofrece una lectura ética de la responsabilidad, aplicada a las organizaciones de la esfera económica de nuestras sociedades. Teniendo como marco de referencia la actual situación de crisis y las medidas que se están planteando de manera general para hacerle frente, en este trabajo se cuestiona críticamente el protagonismo otorgado a la responsabilidad en ese escenario y subraya las debilidades de su vertiente hegemónica. A partir de aquí,el texto recoge una llamada a rescatar otros rostros de la responsabilidad que tienen mayor entidad ética y exigen mayor densidad política, y propone recuperar el valor edificante de la responsabilidad, que llama y nos obliga a todos a cuidar la sociedad que todos componemos. La eficacia o adecuación de las distintas políticas, estrategias y herramientas para la promoción de la responsabilidad social deben responder a los retos que este valor edificante de la responsabilidad propone.
Peregrinaciones y turismo. El Camino de Santiago
Authors: Leira López José , Rego Veiga Gustavo , Santos Pita Manuela del Pilar
Published: August 2020

En este artículo se lleva a cabo, en primer lugar, una aproximación al concepto del turismo en general y del turismo cultural en particular dentro de una concepción del desarrollo sostenible. A continuación se reflexiona sobre las claves del fenómeno de las peregrinaciones, sus tesis explicativas y las funciones que cumplen. Posteriormente se realiza un paralelismo entre el turismo cultural y la peregrinación a Compostela, donde se establece una tipología de los visitantes y sus motivaciones, al tiempo que se analiza el consumo de productos y símbolos que llevan a cabo los turistas y los peregrinos. Por último, se reflejan las posibilidades de desarrollo socioeconómico que todo ello conlleva.
El turismo como factor estratégico de desarrollo rural: el Camino de Santiago francés
Authors: Andrade Suárez María José , Leira Landeira Grial , Caramés Valo Rosa
Published: August 2020

El potencial turístico adquiere cada vez una mayor importancia como motor dinamizador de las zonas rurales que, inmersas en una profunda crisis económica y social, disponende un enorme patrimonio natural y cultural. De acuerdo con este planteamiento, la red de los Caminos de Santiago puede ser considerada como una buena prueba de ello. Bajo esta premisa, se trata de estudiar en la presente investigación la potencialidad del Camino de Santiago Francés como alternativa para el desarrollo socioeconómico de los espacios rurales por los que transcurre. La hipótesis inicial se basa en que esta modalidad de turismo ha servido para relanzar el desarrollo socioeconómico de los municipios rurales camineros. Se analizarán los resultados a partir de los datos referidos al tramo gallego del Camino Francés, la ruta principal y más frecuentada, que abarca un total de catorce municipios pertenecientes a las provincias de Lugo y A Coruña en el período comprendido entre 1991 y 2005. Las variables objeto de examen seleccionadas como indicadores de la acción dinamizadora del Camino corresponden al movimiento demográfico, la cuota de mercado y el número de licencias comerciales,así como el índice turístico.
El culto mariano del Rosario de Pompeya
Authors: Aloj Eugenia , Zollo Anna
Published: August 2020

El trabajo enfrenta diferentes aspectos del nacimiento y evolución del turismo religioso en Pompeya. Son tomados en consideración los diferentes aspectos de la tipología de culto mariano de Pompeya, las varias expresiones de fe y la característica dominante de la devoción respecto a la Virgen del Rosario, definida por sus aspectos devocionales justamente “sacro popular”.
energías renovables y las TIC en la construcción de una nueva Colombia
Authors: Ríos-Alvarado Arnaldo
Published: August 2020

La energía es un recurso indispensable para “el desarrollo” de un territorio donde, a través de un entramado interre- lacional con la sociedad y la naturaleza, garantiza la ordenación energética de un territorio, para lo cual requiere una política energética que alcance las dimensiones del derecho social de las energías encaminadas a la socialización, la transparencia de los procesos y la regulación jurídica y técnica alineadas a los intereses del “desarrollo económico” y social de nuestra nación.
Peripheral ossifying fibroma- A case report with brief review
Authors: C S Banushree , M Dharanya , V Bhat Ramachandra , S Devakumari
Published: August 2020

Peripheral ossifying fibroma (POF) is an inflammatory reactive hyperplasia of gingiva. It occurs frequently in anterior maxilla with a higher predilection for females. It presents as sessile mucosal nodule and more common in second decade of life. It has been suggested as a separate clinical entity rather than a transitional form of pyogenic granuloma. Diagnosis is often challenging as the clinical presentation of POF mimicks other reactive lesions of gingiva. Due to its high recurrence rate of 8.9% to 20%, prompt diagnosis is important. Here, we report a case of 15 year old girl with pedunculated lesion in gingival and clinically diagnosed as traumatic fibroma.
Sługa Boży Antoni Henryk Szuman – tercjarz franciszkański
Authors: Dalecki Krzysztof
Published: August 2020

Artykuł poświęcony jest postaci ks. prałata Antoniego Henryka Szumana, który przewodniczy II grupie męczenników Diecezji Pelplińskiej, z okresu II wojny światowej, w trwającym obecnie procesie beatyfikacyjnym. Tekst jest próbą zarysowania, do tej pory jeszcze najmniej znanej aktywności tego kapłana, a mianowicie jego pracy w ramach Trzeciego Zakonu św. Franciszka z Asyżu. Najpierw nakreślony został tu bardzo ogólnie stan tercjarstwa w Polsce oraz jego działalność. Następnie opisane zostały funkcje i przedsięwzięcia realizowane w tym zgromadzeniu przez pelplińskiego Sługę Bożego.
Prevalence of patterns of impacted third molars
Authors: Hosseini Seyed Hadi , Mazareii Fard Zahra , Maleki Donya
Published: August 2020

Aim: As the patterns of impaction can affect the treatment plan of removing or remaining the impacted tooth, the difficulty of surgery, and the post-surgical complications, this survey aimed for assessment of the mandibular wisdom tooth impaction patterns in terms of angulation and depth in the north population of Iran.
Materials and Methods: 196 Panoramic radiographs were gathered from patients attending to the department of oral and maxillofacial surgery of GUMS in 2018-2019. To perform this retrospective study the prevalence of impaction, angulation, and the level of the eruption were assessed. The data were analyzed by SPSS 16.
Results: This study found that the most common pattern of impacted mandibular third molars was level B in terms of depth and mesioangular in terms of angulation.
Conclusion: The current study notes the importance of determining the angulation and level of wisdom tooth in designing the pre-surgical treatment and in post-surgical complaints
Removable prosthetic treatment of an ectodermal dysplasia patient: A case report
Authors: Atri Faezeh , Azizi Sania , Hatampour Sepehr
Published: August 2020

Ectodermal dysplasia is an inherited disorder with partial or complete anodontia. Early dental treatments are mandatory for improving child mastication, communication, and esthetic. There are various treatment approaches such as implant-retained prosthesis, fixed and removable denture which should be selected according to remained teeth, oral and facial parameters. This clinical study describes the prosthetic treatment of a child with ectodermal dysplasia with combination ofcomplete overdenture and partial removable denture.
Identification Of Health, Safety, and Environment Aspects In Cement Factory Using AHP And FMEA Techniques
Authors: Moradi Mohamad , Malmasi Saeed , Babaei Pouya Amin
Published: August 2020

Background and aims: Cement production processes are associated with different hazards, such as health and safety hazards and environmental pollution. The current study was conducted to evaluate and determine the safety, health, and environmental risks of using FMEA and AHP techniques in the cement factories while providing certain suggestions for controlling them.Methods: The study was conducted as a case in one cement factory in 2019. The checklists for FMEA and AHP techniques were filled out by the evaluation team. The risks were identified and prioritized. Controlled approaches were suggested for the identified risks. Results: In this study, 101 risk cases were evaluated and categorized in various units of the factory, such as manufacturing and service units. The results of FMEA technique showed that crushing, crushing monitoring, milling, filtration, and pre-heater sections had the highest degree of health and safety risks. The results of AHP technique also showed that the environmental pollution caused by the removal of electro filter from the circuit, electro fan burning caused by over current, the failure of the equipment and process, and the defect in the filtration system were all prioritized.Conclusion: Through taking technical-engineering measures, adopting comprehensive HSE management solutions, such as changes in the work process, making replacements in parts and used machinery, installing recyclable systems, repairing and maintaining the system of air pollution protection, installing a warning and responsive system, mechanizing activities, shielding, implementing instructions and regular curriculum can greatly reduce the risk level.
Determination of Minimum Data Set for Designing a Diagnosis Decision Support System and Medication Follow-Up for Multiple Sclerosis
Authors: Khenarinezhad Sahar , Mohammadzadeh Niloofar , GhaziSaeedi Marjan , NaserMoghadasi Abdorreza
Published: August 2020

Background and Purpose: Diagnosis of multiple sclerosis (MS) is complicated because of the lack of definite factor. Decision support systems are expert systems which help physicians in decision-making process. First step in designing the system is identification of a minimum dataset (MDS). This study aimed to determine minimum dataset required to design diagnosis decision support system.Materials and Methods: This research was a descriptive cross-sectional study. Data were gathered from medical guideline approved by Ministry of Health, Treatment and Medical Training, Multiple Sclerosis diagnosis, international guideline of Royal college of England, and McDonald Diagnostic criteria. Data collection tool was a designed checklist consisting of 100 items provided to 25 neurologists and MS fellowships of medical universities and private clinics in Iran.Results: Out of 100 designed information’s items, 10 items were omitted due to CVR less than 0.49. Employment status items, history of MS in 3rd grade relatives, history of viral diseases, orbital MRI, optical coherence tomography, brain CT-scan, ESR, CRP, visually evoked potentials, delay duration of P100 for each eyes are all examples of information elements that have been omitted.Conclusion: Determining the minimum dataset related to MS is an important step in designing diagnosis decision support system and medication follow-up. Therefore, MDSs can help those responsible for gathering standard information of patients with Multiple Sclerosis (MS), and causes improvement in management of information for this disease.
Collaborating with the Disability Rights Community: Co-Writing a Code of Ethics as a Vehicle for Ethics Education
Authors: Tarvydas Vilia , Hartley Michael , Jang Yoo Jin , Johnston Sara , Moore-Grant Nykeisha , Walker Quiteya , O'Hanlon Chris , Whalen James
Published: August 2020

An ethics project is described that challenged students to collaborate with disability rights authorities to co-write a code of ethics for a Center of Independent Living. Experiential and reflective assignments analyzed how the construction of knowledge and language is never value-neutral, and people with disabilities need to have a voice in decisions that affect their lives. Insights from the project suggest considerations for teaching students to construct ethical knowledge that is empathetic and respectful to the culture for which a code of ethics will be applied, in this case, the experience of disability from a social model perspective.
Nurses' Moral Experiences of Ethically Meaningful End-of-Life Care: Distress, Resilience, Responsibility, and Care
Authors: Ma Kristina , Wright David Kenneth , Vanderspank-Wright Brandi , Peterson Wendy E. , Carnevale Franco A.
Published: August 2020

Background

Moral distress, the phenomenon in which an agent is constrained in acting on their ethical choice, is a reoccurring theme in the literature on nurses' experiences of end-of-life care (EOLC). Understanding moral engagement solely through a lens of moral distress can be limiting—as such, we sought to explore the diverse experiences nurses consider ethically meaningful in their palliative and EOLC practice.

Purpose and Methods

This article presents an exploration and analysis of stories told to us, within an interpretive description study, by five nurses practicing in EOLC in diverse settings across Canada. Although these stories were told to us in a research context, the purpose of this theory article is to explore what these stories demonstrate about the moral engagement of nurses caring for dying patients.

Findings

Our analysis suggests that while moral distress is a feature of nursing stories, so too are many other dimensions of moral experience, including resilience, responsibility, and care.

Implications for Practice

Expanding how we understand nurses' moral engagement in the care of dying patients has implications for how we account for the many responsibilities that nurses shoulder in striving to provide “good” care to people at the end of life.
Zróżnicowanie kontroli efektywności form finansowania sportu przez gminę
Authors: Durbajło-Mrowiec Małgorzata
Published: August 2020

Gminy dobrowolnie realizują głównie dwa zadania — z zakresu sportu i rekreacji oraz kultury. W większości działają kluby sportowe, w tym kluby ludowe na wsiach. Wydatki na kulturę fizyczną stanowią kilka procent wydatków budżetowanych. Celem artykułu jest udzielenie odpowiedzi na pytanie, czy mimo stosunkowo małych wydatków na sport, w relacji do innych tytułów, gminy kontrolują efektywność wydatkowanych środków na to dobrowolne zadanie. W tym celu przeprowadzono analizę aktów prawnych, regulujących możliwe formy wydatkowania środków na sport w gminach. Autorka wykorzystała również wiedzę pozyskaną w ramach współ-pracy z gminami. Zastosowano głównie dwie metody badawcze: badania dokumentów źródłowych i obserwację. Przeprowadzone badania upoważniają do sformułowania wniosku — gminy nie oceniają efektywności wydatków na sport. Takie postępowanie jest sprzeczne z zasadami wydat-kowania środków publicznych. Każdy wydatek powinien być celowy, oszczędny i efektywny. Zaproponowane przez autorkę mechanizmy oceny efektywności wydatków są adekwatne do przyj-mowanych w gminach rozwiązań organizacyjnych realizacji zadań w zakresie sportu i tym samym form ich finansowania. Dla zapewnienia skuteczności zaproponowanych mechanizmów, należy je włączyć w system kontroli zarządczej gminy.
Waluty krajowe czy wspólnotowe? Oto jest pytanie!
Authors: Kwaśnicki Witold
Published: August 2020

What currency system is conducive to economic development? Economists from various economics schools are trying to answer this question.Different opinions of economists advocating the existence of a global currency as well as those who believe that there should be competition between currencies and the associated ‘free banking’ have been presented. The problems associated with the concept of optimal currency areas are also discussed. The last section discusses the controversy surrounding the question: “monetary commun-ities or national currencies?”.
Zmiana zachowań rynkowych pokolenia Z
Authors: Paczka Edyta
Published: August 2020

This article presents considerations on the changes of the consumer behaviour of generation Z, manifested in the way purchasing decisions are made and needs are met. The purpose of this article is to analyse the conditions for the development of new forms of purchasing processes and alterna-tive consumption patterns. The author pointed out factors causing young purchasers’ increased in-terest in innovative solutions in the sphere of consumption, and, in particular, the expanding scope of internet communication and the scale of use of mobile devices. It has been proved that the gen-eration Z consumption model is strongly embedded in virtual reality and includes an alternative approach to satisfying needs. An attempt was made to answer the question regarding the reason for a change in approach of the youngest generation to consumption and the development of new trends, and in particu-lar of the resignation from purchasing goods in favour of gaining access to them. The author indicated certain premises increasing generation Z’s inclination to use some goods or services only when required, and not acquiring them for personal possession, including, in particular, growing awareness of the negative social and environmental consequences of excessive consump-tion. Benefits of adapting the collaborative consumption model in the form of prosumer activities were highlighted. The presented topic allowed to show the changing approach to consumption as a challenge for enterprises facing the need to react both to the changing mobile technological environment and to the new, emerging generation of consumers. So far, this problem has not been studied in detail, therefore the conclusions of the article on changing consumer attitudes of gen-eration Z may be used by manufacturers to take actions consistent with the expectations of this significant group of young, mobile buyers.