bluuebunny/crossref_metadata_2025 huggingface dataset:
Términos genéricos y función léxica 'Gener' en la teoría Sentido-Texto
Authors: Sanromán Vilas Begoña ,   Universidad de Helsinki
Published: July 2024

Dentro de la teoría Sentido-Texto, la función léxica Gener forma parte de un sistema de codificación para formalizar las relaciones léxicas de una lengua. En concreto, Gener perfila una relación léxica paradigmática que da como valores términos que representan conceptos genéricos para la palabra llave a la que se aplica. Así, asiento sería un término genérico para silla, sofá o taburete, y sentimiento, para tristeza, alegría o dolor. Sin embargo, a pesar de la gran versatilidad de esta función léxica como herramienta teórica y práctica, su definición plantea algunas cuestiones: 1) ¿Son los valores de Gener del tipo asiento términos hiperónimos? En caso afirmativo, ¿cómo podemos verificarlo? 2) ¿Es Gener una relación léxica estrictamente paradigmática, a la luz de expresiones como sentimiento de alegría, en las que la palabra llave se combina con su valor? Si no es así, ¿cómo habría de clasificarse Gener, como una relación léxica mixta o como dos relaciones léxicas diferentes? El estudio ahondará en la naturaleza teórica de Gener para ofrecer una respuesta a las cuestiones planteadas, y establecer sus semejanzas y diferencias con otros conceptos de sentido general surgidos en el panorama lingüístico contemporáneo, los nombres ligeros y los nombres encapsuladores.
Estructuras seudocoordinadas: perífrasis y significados aspectuales
Authors: Malena Kornfeld Laura ,   Universidad de Buenos Aires Consejo Nacional de Investigaciones Científicas y Técnicas (Conicet)
Published: July 2024

Este artículo se propone indagar en las propiedades gramaticales y el significado de las estructuras seudocoordinadas: agarra y les paga; va y se muere, que se registran en variedades coloquiales de distintos países hispanoparlantes. La seudocoordinación da lugar a construcciones gramaticalizadas de dos formas verbales (flexionadas en las mismas categorías morfológicas y unidas por la conjunción y) que designan un único evento, dado que el primer verbo de cada secuencia está desemantizado o gramaticalizado. Un dato relevante es que los mismos verbos gramaticalizados que intervienen en estructuras seudocoordinadas (e.g., además de agarrar e ir, venir, coger, pillar, saltar llegar y también otros más novedosos: volver, arrancar, largarse, lanzarse, ponerse, meterse, mandarse) funcionan (o funcionaron) como auxiliares de perífrasis, a menudo con valor incoativo. Empíricamente, nos enfocamos en determinar la distribución gramatical de las estructuras seudocoordinadas, diferenciándolas de las perífrasis incoativas, con el fin de ofrecer un análisis sintáctico y semántico de estas construcciones. El recorrido nos permitirá concluir que el significado primario de las estructuras seudocoordinadas gramaticalizadas es el aspecto aoristo (Smith 1991 y Camus Bergareche 2004), en línea con Coseriu (1966) y en oposición a perspectivas recientes como García Sánchez (2007) y Jaque et al. (2018, 2019).
Kemampuan Spasial Dalam Menyelesaikan Soal Geometri
Authors: Jumriani  , Rahman Abdul
Published: July 2024

This research includes qualitative research. This research aims to determine spatial abilities in solving flat-sided geometric shape problems. The trial respondents in this research were 3 students in class IX9 of SMP Negeri 1 Parepare. The spatial ability assessment consists of a test sheet and an interview guide sheet. The spatial abilities produced in this research are indicated to meet the spatial ability indicators.
Data analysis in this research went through data reduction, data presentation, and concluding/verification. The research results show that students show spatial abilities (1) Able to compare or connect cubes with blocks. (2) Knowing the number of small cubes that can fill the block. (3) Know how to calculate the volume of the beam.
Pengaruh Penggunaan Media BAPER Terhadap Kemampuan Numerasi Siswa SDN 80 Liangbai
Authors: Nur Isra
Published: July 2024

The purpose of this study was to find out that the use of multiplication rod media (BAPER) had a positive effect on the mathematical numeracy abilities grade students of class IV UPTD SD Negeri 80 Liangbai. This type of is a quasi- eksperimental research (quasi-eksperimental) involving the control class and the eksperimental class with a nonequivalent control group design. The variables studied in this study were the mathematical numeracy abilities grade students of class IV UPTD SD Negeri 80 Liangbai as the dependent variable and the use of BAPER media as the independent variable.
            The population of this research is the grade students of class IV UPTD SD Negeri 80 Liangbai in the odd semester of the 2022/2023 academic year which consists of two classes. The sample of this class IV A and class IV B, each of which consisted of fifteen students obtained using a saturated sample. The research data was obtained using a research instrument in the form of a student’s mathematical numeracy ability test. Based on descriptive statistical analysis, it was obtained that the average value of student’s numeracy skills in the control class for posttest data was 70.00 with medium ability category and standard deviation of 6,503 while in the experimental class the average value of student’s numeracy abilities for  posttest data  was 80.27 with medium ability category and standars deviation of 5,934 and the inferential using the test of the large effect of the treatment obtained the value of r2= 0,19 with a percentage of 19% which is in the category of medium effect anda has an effect on student’s numeracy abilities. so it can be concluded that the use of multiplication rod media (BAPER) has a positive effect on the numeracy skills grade of IV UPTD SD Negeri 80 Liangbai.
Pengaruh Model Pembelajaran Course Review Horay Berbantuan Media Kartu Masalah Terhadap Kemampuan Pemecahan Masalah
Authors: Inka Inka Angreni , Abdul Rahman  , Asdar Dollo
Published: July 2024

This study aims to find out that the application of the Course Review Horay learning model has a positive effect on the problem solving abilities of class VII UPTD students of SMP Negeri 1 Parepare. This type of research is a type of experimental research. The variables studied in this study were the problem solving abilities of class VII UPTD SMP Negeri 1 Parepare as the dependent variable and the application of the course review horay learning model as the independent variable. The population of this study was students of class VII UPTD SMP Negeri 1 Parepare for the 2022/2023 academic year consisting of 10 (ten) classes. Sampling used Cluster Sampling or stratified random sampling, from 10 classes one class was taken randomly, namely class VII.5 as the experimental class. The instruments used in this study were problem solving ability tests (pretest & posttest) and validated student activity observation sheets. Based on descriptive statistical analysis, the average value of mathematics learning outcomes before applying the course review horay learning model was 35.63 and the average value of mathematics learning outcomes after applying the course review horay learning model was 72.19. Based on the inferential statistical analysis using the One Sample t-test, a significant value was obtained, p = 0.000 < 0.05, this means that H0 is rejected and H1 is accepted. So it can be concluded that the application of the course review horay learning model has a positive effect on the problem solving abilities of class VII UPTD SMPN 1 Parepare.
Study of phase equilibria in the two-component organic system biphenyl – n-docosane
Authors: Kazakova A. I. , Garkushin I. K. , Yakovlev I. G.
Published: July 2024

The fusibility diagram of the diphenyl – n-docosane system was calculated by Schroeder, UNIFAC and UNIFAC Dortmund methods, and it was shown that it belongs to the eutectic type. Individual substances and their mixtures were studied experimentally using a differential scanning microcalorimeter. The endo-effect corresponding to the melting of the eutectic was noted on the DTA heating curve of the eutectic alloy. A comparison of the eutectic coordinates calculated by these methods with experimental data is presented. Specific fusion enthalpy, molar values of entropy and enthalpy of fusion, volumetric specific fusion enthalpy and density for standard conditions were calculated for an eutectic alloy. The eutectic mixture can be used as a heat carrier, as well as a working fluid of a heat accumulator.
DATAWARE AND SOFTWARE OF THE AUTOMATED TECHNOLOGY FOR COMPUTER- INTEGRATED CONTROL OF HEAT PUMP SYSTEMS
Authors: OLISHEVSKYI Illia
Published: July 2024

The paper has solved a scientific and applied problem as for substantiating requirements to technical and functional characteristics of the automated technologies of computer-integrated control of heat pump systems in the heating and cooling modes owing to its dataware and software developing and testing.
Following functional procedures have been taken into consideration during the dataware and software development of the computer-integrated subsystem for heating of buildings: monitoring of ambient air temperature, ground temperature, and operating modes of functional elements of the heat pump system as well as zonal monitoring of indoor air temperature; computer-integrated processing of the monitoring data; automated control of the heat pump as well as modes of zonal thermal medium supply to the building; and analysis of energy efficiency as for implementation of the proposed computer-integrated method to control systems of thermodynamic heating. It has been identified that thermal capacity of a heat pump is rather sensitive to indicators of the total heat losses of a building. If the total heat losses increase from 0.2°С/hour up to 0.5°С/hour then constant value of the thermal capacity increases by 48%. Moreover, thermal capacity of a heat pump is quite sensitive to ambient air temperature dynamics: if temperature variation is 12°С (i.e. 3°С-9 °С) then average increase in thermal capacity is 58 %.
Following functional procedures have been involved during the dataware and software development of the computer-integrated subsystem for cooling of buildings: monitoring of ambient air temperature and operating modes of functional elements of the heat pump system; zonal computer-integrated monitoring of indoor air temperature; computer-integrated the monitoring data processing based upon microcontrollers; automated control of the thermal pump operating modes (i.e. heat energy outfeed and release to the main intercooler unit); and analysis of energy efficiency as for implementation of the proposed computer-integrated method to control systems of thermodynamic cooling of buildings. The abovementioned  has helped identify that thermal capacity of a heat pump is rather sensitive to indicator of heat exchange with surrounding air: four times increase in heat-exchange coefficient (i.e. from 1°С/hour up to 4°С/hour) results in 20% growth of thermal capacity of the cooling subsystem system at similar ambient air temperature (it varies from 30°С up to 36 °С) if the maintained target indoor temperature is 22°С.
Impact of organizational support toward professional skill development and self-learning attitude on the career success of employees from rural background
Authors: Tamilselvan Monika , Israel Densingh Joshua
Published: July 2024

This research is an attempt to empirically analyze how the variables, organizational support for employees’ professional skill development and their self-learning attitude impacts the career success of employees working in the IT sector. Career success has been measured using 8 constructs namely, recognition, authenticity, growth and development, personal life, influence, satisfaction, quality work and meaningful work. Career success acts as the dependent variable. Organizational support and self-learning attitude are the independent variables. The study also attempts to determine if a background from which a person has originated, in other terms, the place of education of the person impacts the relationship between the independent and dependent variables.  Background is measured using a dichotomous variable with options in the instrument as ‘Rural’ and ‘Urban’. Quantitative data is collected from 418 professionals working in the IT sector of Indian companies. Structured equation modeling was used to analyze the data collected. AMOS and SPSS have been used to analyze the data. The results of the analysis show that the place of education or the background from which a person is brought up does not moderate the relationship between self-learning attitude and career growth at organizations.
Investigation Of Cultural Literacy In Early Children Through An ATIK Learning Model
Authors: Azizah Siti Nur , Zubaedah Siti
Published: July 2024

The decline of local culture in Indonesia is due to the heavy influence of foreign culture. So that the younger generation prefers foreign cultures. The decline in local culture is found in early childhood in the present era. So the cultivation of cultural literacy needs to be instilled from an early age at the educational level through appropriate learning models. So that when they grow up, children have knowledge and love for local culture. This study aims to describe and describe how to plan for planting cultural literacy and implementing cultural literacy in early childhood through the ATIK model at RA Bustanul Ulum Jayasakti. The research methodology is using a descriptive qualitative approach, the research location is at RA Bustanul Ulum Jayasakti, Central Lampung. This study used three research subjects, namely the principal and two class teachers. The results of the research conducted were that the RA Bustanul Ulum institution carried out planning in instilling cultural literacy in early childhood through three planning stages, namely planning for selecting activities, planning for budget costs and planning for determining activity schedules. The activities chosen in cultivating cultural literacy through the ATIK model are coloring pictures of traditional cultural clothes, traditional dances, and habituating good manners. With different activity schedules and costs incurred using BOP funds. While the implementation of these activities uses the ATIK model with 3 stages, namely children observing, imitating and doing. Cultivating literacy through careful planning and using the ATIK model makes the goal of cultural literacy achieved
The Influence Of Problem-Based Learning Models On Critical Thinking Skills In Early Childhood
Authors: Hariyani Desi , Haenilah Een Yayah , . Nopiana , Kurniawati Asih Budi
Published: July 2024

The purpose of this study is to determine the effect of the problem-based learning model on the critical thinking abilities of children aged 5-6 years. This type of research uses quantitative with quasi- experimental research methods. Sampling in this study used purposive sampling with the number of samples in this study totaling 20 children and the data collection techniques used were observation and documentation. The data analysis technique used is the Wilcoxon signed rank test. This results of the research showed that the treatment scores using the problem-based learning model and the posttest were increased by 45% for children Developing According to Expectations (DAE) compared to before using the problem-based learning model. The results of the pretest for critical thinking abilities of children who were Beginning to Develop (BD) were 35%. then the final result of the total number of children's pretest and posttest is at the Very Well Developing (VWD) stage of 80%. This shows that there is an influence from using the problem-based learning model on the critical thinking abilities of children aged 5-6 years .
Golput Ditinjau Dari Perspektif Hak Asasi Manusia Dan Maslahah Mursalah
Authors: Muhammad Hasanudin
Published: July 2024

Abstrak
Golput merupakan sebutan yang dialamatkan kepada mereka yang tidak menggunakan hak pilihnya pada saat diadakannya pemilihan umum. Bila menggunakan perspektif hak asasi manusia dalam konteks pemilu, siapapun dan apapun statusnya, maka dia memiliki hak untuk ikut serta memilih atau tidak ikut serta memilih ketika sedang berlangsung kegiatan pemilu. Namun bila menggunakan perspektif hukum, baik itu hukum tata Negara/hukum normatif dan/atau ajaran agama islam, tentu ada pertimbangan-pertimbangan tertentu yang harus diperhatikan, khususnya adalah pertimbangan kemaslahatan yang didalam ajaran islam disebut dengan maslahah. Tulisan ini adalah tulisan kualitatif dengan metode study pustaka, dan menggunakan pendekatan hukum/law approach. Secara hukum normatif Golput tidak dibenarkan, bahkan bagi yang mengajak untuk golput bisa dikenakan ancaman pidana. Sementara itu dari sisi perspektif hukum islam, maka dengan pertimbangan kemaslahatan/ maslahah mursalah gerakan ini juga tidak dibenarkan. Karena memberikan hak suara dalam memilih pemimpin bisa dikatakan sebagai kewajiban setiap rakyat, dan umat islam untuk membuktikan ketaatan rakyat itu terhadap negara/ulil amri dan ketaatan umat tersebut kepada apa yang sudah menjadi syari’at agama.
Kata kunci : Pemilihan umum, Golput, Maslahah/Kemaslahatan.
Abstract
Abstentions are designations addressed to those who did not exercise their right to vote at the time of the general election. When using the perspective of human rights in the context of elections, whoever and whatever their status, then he has the right to participate in voting or not participating when voting takes place. However, when using a legal perspective, be it the state administration law / normative law and / or Islamic religious teachings, of course there are certain considerations that must be considered, in particular the consideration of benefit which in Islamic teachings is called maslahah. This paper is a qualitative writing with a literature study method, and uses a legal approach / law approach. By law normative Abstentions are not justified, even those who invite abstentions can be subject to criminal threats. Meanwhile, from the perspective of Islamic law, it is also not justified by considering the benefit / maslahah of mursalah. Because giving voting rights in choosing a leader can be said as an obligation of every people, and Muslims to prove the people's obedience to the state / ulil amri and the obedience of these people to what has become a religious shariah.
Keywords: General Election, Abstentions, Maslahah/Benefit.
Implementasi Peraturan Daerah Kota Metro Tentang Penanggulangan Penyakit Sosial Masyarakat Terhadap Praktek Prostitusi Online Di Kota Metro
Authors: Salim Choirul
Published: July 2024

ABSTRACT
The problem of prostitution is nothing new in Indonesian society, currently online-based prostitution is increasingly rampant. This phenomenon is a social problem because it involves social and moral values ​​in people's lives. This social problem cannot be overcome if there is no special attention from all parties, both government and society. From this, the authors are interested in conducting research related to the implementation of the Metro City Regional Regulation Number 07 of 2016 concerning Community Social Disease Management, especially the practice of online prostitution in Metro City.
This research is a field research (Field Research) which describes the implementation, obstacles and solutions to the implementation of the Metro City Regional Regulation Number 07 of 2016 concerning Community Social Diseases Management of the practice of online prostitution in Metro City.
Based on the results of the research, it can be concluded that the implementation of the Metro City Regional Regulation Number 7 of 2016 concerning Community Social Diseases Control regarding online prostitution has not been implemented optimally, Satpol PP officers who are in charge of local regulations have taken serious control but sanctions are given to disease perpetrators. social in the community only in the form of social guidance and sanctions. In the regional regulation Number 07 of 2016 concerning Community Social Diseases Management, it has not yet provided clear sanctions to perpetrators of social diseases such as online prostitution, because there are no implementing or guardian regulations regarding these regional regulations. Because the guardian's function explains the articles in regional regulations. The solution is that the local government must issue a guardian or implementing regulations from the Metro City Regional Regulation Number 07 of 2016 concerning Community Social Disease Management and need active participation of all components in tackling social diseases, especially those related to online prostitution.
Keywords: Local Regulation, Implementation, Online prostitution
Efek Efek Kausal Pada Aturan Permohonan Dispensasi Kawin
Authors: Nugraheni Prasasti Dyah
Published: July 2024

This paper contains legal issues arising from the promulgation of the Supreme Court Regulation Number 5 of the Year, which is a legal substance derived from Law Number 16 of 2019. The research method used in this paper is normative legal research which is carried out using secondary data. or library data. Das sollen, as an implication of the new regulation, creates a potential that makes applications for dispensation of marriage wide open. This is evidenced by the existence of a court decision, one of which is Decision Number: 13 / Pdt.P / 2020 / PA.Bgi., Which makes giving dispensation to marriage for those who are not yet old enough, on the basis of consideration of fulfilling administrative requirements, which are in accordance with the provisions of Article 7 paragraphs (1) and (2) of the Marriage Law jo. Article 6 (e) Government Regulation Number 9 of 1975. Therefore, it is very necessary to make new statutory provisions, which are limitative in nature, so that, it is hoped, can minimize deviant practices of the provisions regarding the marriage age limit for women and men who want to get married but not old enough.
Perlindungan Hukum Bagi Karyawan Yang Di PHK Di Era Digitalisasi Industri
Authors: Firmansyah Firmansyah
Published: July 2024

Pemutusan hubungan kerja akibat digitalisasi industri bertentangan dengan hak konstitusional pekerja. Hakikat hak ini menunjukkan bahwa setiap orang berhak mendapatkan penghidupan yang layak dan perlakuan yang adil melalui hubungan kerja yang konstruktif dan proporsional. Hak konstitusional merupakan bagian yang tidak terpisahkan dari hak asasi manusia. Merupakan hak primer, sehingga negara berkewajiban untuk melindungi dan mewujudkannya melalui konstitusi negara dan hukum positif yang ada. Salah satu hak konstitusional yang mendasaradalah perlindungan terhadap pekerja akibat pemutusan hubungan kerja. Namun, terdapat kekosongan hukum terkait perlindungan tenaga kerj Fenomena digitalisasi industri tidak dapat dihindari, pekerja akan sangat dirugikan ketika sebagian besar perusahaan melakukan digitalisasi secara bersamaan demi efisiensi. Perlindungan tersebut harus diatur secara proporsional yang berorientasi pada pemenuhan kepentingan pekerja sebagai dampak dari efisiensi perusahaan akibat digitalisasi. Asas hukum pemberian perlindungan hukum bagi pekerja yang diberhentikan karena digitalisasi meliputi, pertama, asas jaminan perlindungan hukum bagi pekerja dan keluarganya; Kedua, prinsip kompensasi yang adil; Ketiga, prinsip kemauan bersama para pihak yang terlibat dalam hubungan kerja; dan Keempat, prinsip intervensi otoritatif.
Otoritas Sahih Bukhari Sebagai Kitab Hadis Rujukan Dalam Hukum Islam
Authors: Tohari Chamim
Published: July 2024

The study discusses the authority of the traditions in the book of Sahih al-Bukhari, as one of the main sources of reference for hadith in establishing Islamic law after the Qur'an. This study is intended to answer questions about the authority of the Book of Sahih al-Bukhari in terms of historical perspectives, fiqh Qaida, and modern science. This research is library research that uses content analysis as a method of analyzing the data obtained. In addition, this study also uses comparative analysis to answer the problem of hadith authority in Sahih al-Bukhari when viewed from the perspective of Qaida fiqh. In this study, there are three important points, first, the book of Sahih al-Bukhari until now is known as the book of hadith with the highest level of validity compared to other hadith books. However, as a human creation, the book of Sahih al-Bukhari does not escape criticism from its readers, one of which is because Al-Bukhari is considered close to the authorities. Second, in Sahih al-Bukhari there are traditions whose editorials contradict higher texts, and modern science. Third, as a result of al-Bukhari's ijtihad in the field of the authenticity of hadith as well as in the field of fiqh, and his position is sometimes considered higher than other hadith books. The researcher argues that the criticism that states Imam Bukhari was close to the ruler is not appropriate, but the political influence in the writing process cannot be fanned, while regarding the conflict between the hadith texts in the book of Bukhari and the texts of the Qur'an, history, and science, it is necessary deeper study, then the book of Sahih al-Bukhari should be positioned on a par with other hadith books.
INFLUENCE OF FACTORS OF THE PROGRESSION OF DIABETIC RETINOPATHY ON THE CONTENT OF BLOOD SERUM CLUSTER OF DIFFERENTIATION CHEMOKINE CD54 IN THE OF PATIENTS WITH TYPE 2 DIABETES
Authors: Rybachuk O.V.
Published: July 2024

Background. An early critical step in the development of endothelial dysfunction and DR is the adhesion of leukocytes to endothelial cells, which is controlled and mediated by specific adhesion marker molecules CD54 (ICAM-1), CD106 (VCAM-1), P-selectin and E-selectin. However, the influence of DR progression factors on CD54 content in blood serum in patients with type 2 diabetes at different stages of DR is insufficiently covered in the literature.
Aim: to assess the influence of factors of progression of diabetic retinopathy (age, gender, state of diabetes compensation) on the content of the CD54 in the blood serum of patients with type 2 diabetes at different stages of diabetic retinopathy.
Material and methods. An open, one-center, one-moment selective observational study was conducted involving adult patients with type 2 diabetes and DR. The study was conducted in 82 patients with DR (148 eyes). Ophthalmological examination included visometry, perimetry, refractometry, tonometry, biomicroscopy, gonioscopy, ophthalmoscopy, optical coherence tomography. The concentration of the soluble form of CD54 in blood serum was determined by enzyme immunoassay. Statistical analysis included ANOVA and regression analysis. Differences were considered statistically significant if p<0.05.
Results. A probable decrease in serum sICAM-1 concentration with increasing severity of DM in patients with HbA1c>7.5% was revealed, as well as a pronounced tendency to decrease the concentration of soluble CD54 in blood serum at the III stage of DM in patients with type 2 DM with HbA1c> 7,5%. During the progression of DR, a probable increase in the concentration of sICAM-1 at the II stage of DR when using insulin therapy.
Conclusions. The concentration of soluble CD54 in blood serum in patients with HbA1c>7.5% as the stage of diabetic retinopathy increases probably decreases (p=0.05), and in patients on insulin therapy, the content of sICAM-1 in the II stage of diabetic retinopathy is probably higher than in patients, taking tableted hypoglycemic drugs (р=0.003).
RISK FACTORS AND PROGNOSTIC MODELS OF DIABETIC RETINOPATHY AND OPPORTUNITIES OF PRECISION MEDICINE (analytical review)
Authors: Serdyuk A.V.
Published: July 2024

Background. One of the priority directions of modern medicine development is prognostication, the purpose of which is to increase the accuracy and reliability of forecasts of outcomes related to diseases. In diabetes mellitus (DM), the task of precision medicine is to adapt diagnostic and treatment methods to subgroups of the population with similar characteristics in order to achieve maximum effectiveness. Currently, most forecasting methods are too narrowly focused on the blood glucose level, which makes the wide implementation of precision medicine approaches promising.
Aim: to determine risk factors, existing prognostic models and possibilities of precision medicine to improve the effectiveness of diagnosis and treatment of diabetic retinopathy (DR).
Materials and methods. The search for sources of Ukrainian and foreign literature for the analytical review was conducted keywords using the open medical scientific database PubMed (USA). At the first stage, 470 sources were selected, of which 46 were selected for this article.
Results. It was established that the progression of DR in the initial stages is a consistent, significant and independent predictor of proliferative DR. The condition of the retina reflects the influence of the systemic environment and, in turn, has prognostic value for cardiovascular, renal and other complications. Most of the new biomarkers have yet to be tested in clinical practice, which requires additional studies to predict DR and clinical outcomes of its treatment. Most models include age, sex, ethnicity, and lifestyle variables as predictors: smoking, medical history, glycated hemoglobin, and DM duration. Increasing age of patients, DM duration and concomitant arterial hypertension are independent predictors of microvascular complications. We collected a database including 359 patients (359 eyes) with type 2 diabetes with DR of varying severity, the results of clinical, ophthalmological and laboratory examinations. Models for predicting progression and effectiveness of individualized treatment are being developed.
IMPACT OF STRESS ON EMOTIONAL HEALTH AND COGNITIVE FUNCTION
Authors: Marakushyn D.I. , Bulynina O.D. , Isaieva I.M. , Karmazina I.S. , Maslova N.M.
Published: July 2024

Background. Emotional stress can have both a positive effect, which is aimed at adaptation, and a negative one, which affects the higher integrative functions of the brain, and also leads to the development of numerous diseases. In this regard, the problem of establishing the influence of stress factors on the emotional state and cognitive function becomes relevant, which creates the prerequisites for a detailed analysis of the scientific data.
Aim: to investigate the impact of chronic stress on emotional health and to determine the impact of stressful factors on human cognitive functions.
Material and methods. The review included 63 articles, which have been selected using the following keywords: «chronic stress», «cortisol», «cognitive functions», «emotions», «memory», in the databases of scientific medical data PubMed, Scopus and Web of Science. An analysis of the existing research results on the impact of stress on emotional health and cognitive functions was carried out.
Results. Stress causes a multiple effect on the human nervous system, leading to structural changes in different parts of the brain such as atrophy and reduction of brain volume and mass with long-term consequences for the nervous system resulting in impaired cognitive abilities and memory. Alteration of neuronal plasticity, caused by chronic stress, due to dendrite atrophy and decreased spinal density may underlie the depressive disorders. Additionally, chronic inflammation, which also results from prolonged stress, can develop depression and disturb cognitive functions. The hippocampus contains the high density of glucocorticoids receptors, thus increased basal concentration of cortisol may result in functional and structural changes in the hippocampus with atrophy and impaired neurogenesis. Chronic stress can affect cognitive function both acutely and chronically. The acute effect is caused by beta-adrenergic effects, while the chronic effect is caused by long-term changes in gene expression mediated by steroid hormones.
Conclusion. Chronic stress with an increased basal concentration of glucocorticoids affects the hippocampus leading to impaired memory, cognition, and thinking, also increases risk of depression, anxiety disorders.
CELIAC DISEASE: NEW POSSIBILITIES FOR DIAGNOSIS AND MANAGEMENT
Authors: Romanukha V.V.
Published: July 2024

Вackground. Celiac disease is an autoimmune disease that occurs in genetically predisposed individuals and is characterized by damage to the mucous membrane of the small intestine due to exposure to gluten. The interest of researchers in gluten-associated diseases is growing every year. The true prevalence of celiac disease is not sufficiently studied due to the rarity of "classic" cases and the higher frequency of atypical and various clinical manifestations of this disease. Manifestation of celiac disease is possible at any age, the disease is more often diagnosed in adults. All this dictates the need to develop new algorithms for examining patients for timely detection and treatment of сеliacia.
Aim: To review updated key consensus documents on the diagnosis and treatment of celiac disease.
Matherials and methods. The results of scientific research related to celiac disease were searched. The studies that are included were selected based on searches in the online databases PubMed, Web of Science, Scopus, Google Scholar and others and relate to the basic methods of diagnosis and management of celiac disease. 110 sources were selected for analysis, of which were used that met the search criteria.
Results. Based on the analysis of experimental and clinical studies, difficulties were identified in diagnosing celiac disease associated with a greater prevalence of extraintestinal manifestations and a rarity of "classical" cases. Methods of approach to the diagnosis of celiac disease in children and adults have been developed, taking into account invasiveness and accessibility. The basic approach in the treatment of celiac disease is a observed gluten-free diet. Regarding the selection of products, the individual characteristics of each patient are taken into account.
Conclusion. To verify the diagnosis, adults and children with suspected celiac disease are recommended to perform esophagogastroduodenoscopy with biopsy of the duodenal mucosa at several points. An alternative method of diagnosis can be a combination of a very high level of antibodies of the imonoglobulin (Ig) A class to tissue transglutaminase (TGAs) and positive antibodies to endomysium (anti EMA) in two blood samples, however, no single analysis is 100% specific for celiac disease, and the diagnostic accuracy varies significantly between different laboratories. The only proven effective treatment for celiac disease is a lifelong gluten-free diet. In the absence of a complete clinical and serological response to diet, treatment goals are determined individually for each patient. The development of new treatments for celiac disease continues.
Use of Digital Platforms Among University Students: A Systematic Literature Review
Authors: Serwornoo Michael Yao Wodui , Danso Samuel , Azanu Benedine , Semarco Stanley Kwame Marcus , Aidoo Ebenezer Ato Kwamena
Published: July 2024

Digital platforms have a high potential for supporting learning processes, especially in higher education. However, there appears to be a limited systematic review of research on the application of digital platforms in higher education. Using a systematic approach, this study analyzes previous research on digital platforms and how these technologies assist university students in their studies and the challenges involved. Examining 76 relevant articles from Scopus, Emerald Insight and ProQuest databases, the findings demonstrate that students' personal development could be accelerated by the practical application of technology through digital learning platforms. Furthermore, by utilizing digital channels, the COVID-19 epidemic has highlighted how crucial strategic management and flexibility are to the higher education sector. The study identified two main themes: digital platforms that support students’ learning and challenges associated with the deployment of digital platforms. Various unexplored areas on the use of digital platforms among university students are highlighted in the study. The review further recommends higher education institutions to offer digital literacy programs that educate students and faculty on using digital platforms, online privacy and data protection.
Improving spatial resolution of chlorophyll-a in the Mediterranean sea based on machine learning
Authors: Yailymov Bohdan , Kussul Nataliia , Henitsoi Pavlo , Shelestov Andrii
Published: July 2024

The objective of this study is to increase the spatial resolution of data on the level of chlorophyll-a in the Mediterranean Sea using satellite images and ground measurements. The goal of this study is to develop an information technology based on machine learning to create chlorophyll-a concentration maps with high spatial resolution for the pilot areas of the Mediterranean Sea. Traditional ground-based methods for measuring chlorophyll-a are time-consuming, expensive, and have limited spatial and temporal coverage. Therefore, satellite observations have become an effective tool for monitoring chlorophyll-a over large areas. Low spatial resolution satellite data such as GCOM-C/SGLI and Sentinel-3 OLCI allow measurements of chlorophyll-a concentration at the sea surface. However, these data have limited accuracy and spatial resolution, which creates challenges for monitoring local changes in coastal zones and small water areas. Tasks: to analyze available satellite data and ground-based measurements of chlorophyll-a for the Mediterranean Sea; to investigate the correlation between satellite data of different spatial resolutions and ground measurements; to select informative features from satellite data for building machine learning models; and to develop models for increasing the spatial resolution of chlorophyll-a based on regression and machine learning algorithms. Obtained results: information technology combining satellite data with ground measurements in the Google Earth Engine cloud platform is proposed; correlations between satellite measurements of chlorophyll-a and ground data are investigated; models based on Random Forest and Multilayer Perceptron with coefficients of determination up to 0.36 and correlation of 0.6 with test data are built; chlorophyll-a maps with a spatial resolution of 10 m are created for the pilot area near Cyprus. Conclusions. The developed information technology allows the effective combination of satellite data of different spatial resolutions and ground measurements to increase the accuracy and detail of chlorophyll-a maps in the Mediterranean Sea. Further research involves improving the preprocessing of satellite data, using more features, involving data from other regions, and applying more sophisticated machine learning models.
Improvement of land cover classification accuracy by training sample clustering
Authors: Andreiev Artem , Artiushyn Leonid
Published: July 2024

The subject of this article is land cover classification based on geospatial data. The supervised classification methods are appropriate for most of the thematic tasks of remote sensing because they provide the opportunity to set the characteristics of the initial classes in the form of a training sample set, in contrast to unsupervised methods. There are many approaches to processing such a set; however, their common disadvantage is that they do not consider the factor of training sample separability. This characteristic indicates the extent to which signatures representing different classes do not overlap. A low degree of separability is inherent in high-level training sample mixing. Thus, separability affects classification accuracy. One possible ways to increase separability is training sample clustering. Considering the above, the goal of this study is to develop a training sample clustering technique to improve land cover classification accuracy by increasing the separability of training samples. The tasks of this work are as follows: 1) develop a method for training sample separability assessment; 2) develop a training sample clustering technique based on training sample separability; 3) test the effectiveness of the developed technique by applying it to experimental land cover classification. In the experiments, two land cover classifications were obtained for each of the two selected study areas (i.e., one before and another after training sample clustering. Six land cover classes were defined for each experiment. The training samples were selected for each class. Conclusions. After the application of the developed technique, an increase in the separability of the training samples was evidenced by the developed separability index. In turn, this approach led to an improvement in land cover classification. For the first experiment, this was evidenced by an increase in the overall accuracy and kappa coefficient by 20% (from 63 to 83%) and 21% (from 60% to 81%), respectively. In the second experiment, the increase was 4% (from 77% to 81%) and 5% (from 66% to 71%), respectively.
Efficiency energy analysis for 6G communication systems using intelligent reflecting surface architecture
Authors: Walidainy Hubbul , Raihan Siti , Adriman Ramzi , Away Yuwaldi , Nasaruddin Nasaruddin
Published: July 2024

The subject of this 6G communication system research is expected to form a hyper-connected network in which various electronic devices can connect continuously without interruption. Several technologies have been built to support 6G communication systems, such as intelligent reflecting surface (IRS). An IRS is a reflector equipped with several two-dimensional passive elements that perform a phase shift by each element, which can reflect electromagnetic (EM) waves coming from the base station (BS) to the user equipment (UE), which is controlled via a controller to increase the signal strength at the UE and overcome poor propagation conditions. IRS can be placed anywhere, such as on a wall or on the roof of a building. The aim of the IRS research is expected to reduce the energy consumption and increase the spectral efficiency of wireless networks using artificial intelligence (AI) with low costs, energy savings, no thermal noise, and fairly small levels of interference. The objective of this research is to evaluate and analyze the energy efficiency (EE), including the achievable rate (AR) and signal-to-noise ratio (SNR), by applying the IRS architecture in a 6G communications system, which uses an operating frequency of 95 GHz and a bandwidth of 800 MHz. Then, the method was based on computer simulation using the Matlab software. In this paper, 6G communication system modeling was proposed. This model uses an urban microcell (Umi) that consists of one base station (BS) with multiple antennas, varying the number of IRS reflecting elements and one user. In this research, AR, SNR, and EE, using the frequency of 95 GHz and simulations with MATLAB@2021a software. The results show that the number of elements as many as 400 is 39% more optimal than the number of elements as many as 40 for the AR results. The SNR results without electromagnetic interference (EMI) are higher than SNR values affected by EMI with SNR results of 100 dBm, and the number of reflecting elements is directly proportional to the SNR results. For 800 elements, the EE value is 26% higher than for 40 elements. Conclusions. The application of IRS in 6G communication systems can increase the AR, SNR, and EE.
Image cryptosystem with image key using integral disproportion
Authors: Avramenko Viktor , Bondarenko Mykyta
Published: July 2024

The subject matter of this article is the process of securing visual data through encryption. The goal of this study is to develop a new approach for image encryption and decryption using an image as a key, where security and performance are comparable or superior to alternatives. The tasks to be solved are as follows: developing a symmetric image cryptosystem for both greyscale and colored images in any format that can use an arbitrary image as a security key; adapting the capabilities of integral disproportionality for image encryption. The encryption method applies an integral disproportion formula for each pair of pixels’ components for both the input image and the key image starting from the first one. The output is a ciphered object represented as an array of real numbers, with decryption being the inverse process. The result is a novel approach to image encryption, proposing a new cryptosystem in which an arbitrary image of varying size, format, or content serves as the encryption key. The proposed symmetric full-encryption cryptosystem is applicable to both greyscale and colored images in any format. The method employs a frequency-based approach that influences the values of pixels rather than their positions. In contrast to mainstream approaches in this area, the representation of a cipher is not an image but a binary array. The proposed algorithm is simple to implement. The proposed method appears to meet the required requirements in both security and performance. Conclusions. The scientific novelty of the results obtained is as follows: This research introduces a new image encryption method, which is unique in its application of integral disproportionality to alter pixel values, differing from traditional encryption methods. This provides a practical yet secure option to the existing encryption techniques.
Review about Organic-Inorganic Perovskite Single Crystal : Synthesis Methods, Properties and Applications
Authors: Monik N. Maisuriya  , Priyanka Desai
Published: July 2024

Due to their easy synthesis and exceptional optoelectronic characteristics, such as their long carrier diffusion length, high carrier mobility, low trap density, and tuneable absorption edge ranging from ultraviolet (UV) to near-infrared (NIR), perovskite single crystals have attracted a lot of attention in recent years. These properties have the potential to be used in solar cells, photo-detectors (PDs), lasers, and other devices. In this review provides detailed information about the synthesis methods and applications of perovskite single crystals.
Polifenóis totais de Aloysia gratissima e biodisponibilidade depois de um tratamento oral subcrônico em ratos Wistar
Authors: Schreiner Gênifer Erminda , Schmitt Elizandra Gomes , Santos Laura Smolski dos , Sarmento Silvia Muller de Moura , Maders Luana Tamires , Brites Gabriela Escalante , Pereira Camila Berny , Malheiros Rafael Tamborena , Dartora Nessana , Manfredini Vanusa
Published: July 2024

The present work carried out the quantification of total polyphenols in the aqueous extract of the leaves of Aloysia gratissima, and its oral absorption index in Wistar rats. For this, 20 adult rats were divided into five treatment groups: saline solution; 100 mg/Kg of A. gratissima extract; 50 mg/Kg and 100 mg/Kg of rutin and co-treatment with 50 mg/Kg of extract and 10 mg/Kg of rutin, performed orally for 14 days. For the quantification of total polyphenols, the Folin Ciocalteau method was used. In the extract, the concentration of total polyphenols was 7.11 mg GAE/mL, in the plasma of control animals the baseline level was 4.3 mg GAE/mL. In the treated groups, significantly higher values were observed, of 9.32 mg GAE/mL, 6.65 mg GAE/mL, 8.34 mg GAE/mL and 10.14 mg GAE/mL, respectively. Such data configure A. gratissima as a good source for obtaining total polyphenols due both to its high concentration in the extract and also to their good bioavailability.